diff --git a/.gitattributes b/.gitattributes index a6344aac8c09253b3b630fb776ae94478aa0275b..d45c6653deffa0bef1dc914712396a20abf0a681 100644 --- a/.gitattributes +++ b/.gitattributes @@ -33,3 +33,5 @@ saved_model/**/* filter=lfs diff=lfs merge=lfs -text *.zip filter=lfs diff=lfs merge=lfs -text *.zst filter=lfs diff=lfs merge=lfs -text *tfevents* filter=lfs diff=lfs merge=lfs -text +*.png filter=lfs diff=lfs merge=lfs -text +*.p filter=lfs diff=lfs merge=lfs -text diff --git a/Dockerfile b/Dockerfile new file mode 100644 index 0000000000000000000000000000000000000000..d116d076c3f2a92553211017ebecc092662abbb0 --- /dev/null +++ b/Dockerfile @@ -0,0 +1,12 @@ +FROM python:3.9 +RUN useradd -m -u 1000 user +USER user +ENV PATH="/home/user/.local/bin:$PATH" +WORKDIR /app + +COPY --chown=user ./requirements.txt requirements.txt +RUN pip install --no-cache-dir --upgrade -r requirements.txt + +COPY --chown=user . /app +EXPOSE 7860 +CMD ["uvicorn", "app:app", "--host", "0.0.0.0", "--port", "7860"] \ No newline at end of file diff --git a/app.py b/app.py new file mode 100644 index 0000000000000000000000000000000000000000..ae205cde08f4ef2fe81fa10297b6d474752b26ae --- /dev/null +++ b/app.py @@ -0,0 +1,17 @@ +from fastapi import FastAPI, WebSocket + +app = FastAPI() + + +@app.get("/") +async def root(): + return {"status": "ok", "service": "Code2MCP-esm"} + + +@app.websocket("/ws") +async def websocket_endpoint(ws: WebSocket): + await ws.accept() + await ws.send_text("WebSocket is up. Replace with your MCP/ESM handler.") + await ws.close() + + diff --git a/esm/mcp_output/README_MCP.md b/esm/mcp_output/README_MCP.md new file mode 100644 index 0000000000000000000000000000000000000000..9b36a895087f4a68374178afec5fe2f032fc5d51 --- /dev/null +++ b/esm/mcp_output/README_MCP.md @@ -0,0 +1,144 @@ +# ESM: Evolutionary Scale Modeling for Protein Sequences + +## Overview + +`facebookresearch/esm` is an open-source project developed by Facebook AI Research (FAIR) for deep learning-based protein sequence modeling. It provides state-of-the-art tools for analyzing and predicting protein structures, functions, and variant effects using advanced language models and deep learning techniques. + +### Key Features + +- **Protein Language Models**: Pretrained models like ESM-1 and ESM-2 capture semantic information in protein sequences. +- **Multiple Sequence Alignment (MSA) Modeling**: Tools for protein modeling based on MSA, including MSA Transformer. +- **Inverse Folding**: Predict how protein sequences fold into 3D structures. +- **Variant Effect Prediction**: Assess the impact of mutations on protein functionality. +- **Contact Prediction**: Predict residue-residue contacts in protein sequences. +- **Metagenomic Analysis**: Analyze environmental protein sequences using the ESM Metagenomic Atlas. +- **Feature Extraction**: Tools like `esm-extract` for extracting features from pretrained models. + +This repository is designed for researchers and developers in computational biology, bioinformatics, and related fields. + +--- + +## Installation + +### Prerequisites + +- Python 3.8 or later +- PyTorch 1.8 or later +- GPU support (optional but recommended for large-scale computations) + +### Installation Steps + +1. Clone the repository: + ``` + git clone https://github.com/facebookresearch/esm.git + cd esm + ``` + +2. Install dependencies: + ``` + pip install -r requirements.txt + ``` + +3. (Optional) Set up a virtual environment: + ``` + python -m venv esm_env + source esm_env/bin/activate + ``` + +4. Install the package: + ``` + pip install . + ``` + +5. (Optional) Install additional dependencies for specific features: + ``` + pip install fairscale pandas + ``` + +--- + +## Usage + +### Loading Pretrained Models + +The repository provides pretrained models for various tasks. You can load a model using the following example: + +``` +from esm.pretrained import load_model_and_alphabet +model, alphabet = load_model_and_alphabet("esm2_t33_650M_UR50D") +``` + +### Command-Line Tools + +The repository includes several command-line tools for common tasks: + +#### 1. `esm-extract` +Extract features from protein sequences using pretrained models. + +**Usage:** +``` +esm-extract --model esm2_t33_650M_UR50D --fasta input.fasta --output output.pt +``` + +#### 2. `esm-fold` +Predict the 3D structure of a protein sequence. + +**Usage:** +``` +esm-fold --model esm2_t33_650M_UR50D --fasta input.fasta --output output.pdb +``` + +--- + +## Available Tools and Endpoints + +### Core Modules + +- **`esm.pretrained`**: Load pretrained models. + - Functions: `load_model_and_alphabet`, `load_model_and_alphabet_local` +- **`esm.data`**: Handle protein sequence data. + - Functions: `Alphabet`, `BatchConverter` +- **`esm.inverse_folding`**: Tools for inverse folding tasks. + - Functions: `load_inverse_folding_model` + - Classes: `GVPTransformerEncoder`, `GVPTransformerDecoder` +- **`esm.model`**: Core model definitions. + - Classes: `ESM1`, `ESM2`, `MSATransformer` + +### CLI Commands + +- **`esm-extract`**: Extract features from protein sequences. +- **`esm-fold`**: Predict protein 3D structures. + +--- + +## Notes and Troubleshooting + +### Notes + +1. **Model Size**: Pretrained models like ESM-2 are large and may require significant memory. Use a GPU for optimal performance. +2. **Dependencies**: Ensure all required dependencies are installed. Optional dependencies like `fairscale` and `pandas` are needed for specific features. +3. **Input Formats**: Protein sequences should be provided in FASTA format for most tools. + +### Troubleshooting + +- **Out of Memory Errors**: If you encounter memory issues, try reducing batch size or using a smaller model. +- **Installation Issues**: Ensure you are using a compatible Python and PyTorch version. +- **Model Loading Errors**: Verify the model name and ensure the model weights are downloaded correctly. + +--- + +## Contributing + +We welcome contributions to improve the repository. Please follow the guidelines in the `CONTRIBUTING.md` file. + +--- + +## License + +This project is licensed under the MIT License. See the `LICENSE` file for details. + +--- + +## Acknowledgments + +This repository is developed and maintained by Facebook AI Research (FAIR). For more information, visit the [official repository](https://github.com/facebookresearch/esm). \ No newline at end of file diff --git a/esm/mcp_output/analysis.json b/esm/mcp_output/analysis.json new file mode 100644 index 0000000000000000000000000000000000000000..0b45e6a4f2c478521f173dcdcf572c5f97051944 --- /dev/null +++ b/esm/mcp_output/analysis.json @@ -0,0 +1,163 @@ +{ + "summary": { + "repository_url": "https://github.com/facebookresearch/esm", + "summary": "Repository: facebookresearch/esm\nCommit: main\nFiles analyzed: 100+\n\nEstimated tokens: 500k+", + "file_tree": "...", + "content": {}, + "processed_by": "gitingest", + "success": true + }, + "structure": { + "packages": [ + "source.esm", + "source.scripts", + "source.examples" + ] + }, + "dependencies": { + "has_environment_yml": true, + "has_requirements_txt": true, + "pyproject": false, + "setup_cfg": false, + "setup_py": true + }, + "entry_points": { + "imports": [], + "cli": [], + "modules": [] + }, + "llm_analysis": { + "core_modules": [ + { + "package": "source.esm", + "module": "__init__", + "functions": [], + "classes": [], + "description": "Entry point for the ESM core module, may expose some core APIs." + }, + { + "package": "source.esm", + "module": "pretrained", + "functions": [ + "load_model_and_alphabet", + "load_model_and_alphabet_local" + ], + "classes": [], + "description": "Provides functionality to load pretrained models, either from local or remote sources." + }, + { + "package": "source.esm", + "module": "data", + "functions": [], + "classes": [ + "Alphabet", + "BatchConverter" + ], + "description": "Module for handling protein sequence data, including alphabet definition and batch conversion." + }, + { + "package": "source.esm", + "module": "inverse_folding", + "functions": [ + "load_inverse_folding_model" + ], + "classes": [], + "description": "Core module for inverse folding tasks, containing the Geometric Vector Perceptron (GVP) architecture." + }, + { + "package": "source.esm", + "module": "model", + "functions": [], + "classes": [ + "ESM1", + "ESM2", + "MSATransformer" + ], + "description": "Core model definition module, including ESM-1, ESM-2, and MSA Transformer." + }, + { + "package": "source.examples", + "module": "lm_design", + "functions": [ + "generate_fixed_backbone", + "generate_free_backbone" + ], + "classes": [], + "description": "Protein language model design module, supporting fixed backbone and free generation." + }, + { + "package": "source.examples", + "module": "variant_prediction", + "functions": [ + "predict_variant_effect" + ], + "classes": [], + "description": "Variant effect prediction module, assessing the functional impact of mutations in protein sequences." + }, + { + "package": "source.scripts", + "module": "extract", + "functions": [ + "extract_features" + ], + "classes": [], + "description": "Utility module for extracting features from models." + }, + { + "package": "source.scripts", + "module": "fold", + "functions": [ + "predict_structure" + ], + "classes": [], + "description": "Utility module for predicting protein structures." + } + ], + "cli_commands": [ + { + "command": "esm-extract", + "description": "Extract features for protein sequences from a pretrained model." + }, + { + "command": "esm-fold", + "description": "Predict protein structures using the ESM model." + } + ], + "import_strategy": { + "primary": "import", + "fallback": "cli", + "confidence": 0.9 + }, + "dependencies": { + "required": [ + "torch", + "fair-esm", + "requests", + "biopython" + ], + "optional": [] + }, + "risk_assessment": { + "import_feasibility": 0.9, + "intrusiveness_risk": "low", + "complexity": "high" + } + }, + "deepwiki_analysis": { + "repo_url": "https://github.com/facebookresearch/esm", + "repo_name": "esm", + "analysis": "### Analysis Report: GitHub Repository `facebookresearch/esm`\n\n#### 1. What are the main functions and purposes of this repository?\n\n`facebookresearch/esm` is an open-source project developed by Facebook AI Research (FAIR) primarily for deep learning modeling of protein sequences. Its core objective is to analyze and predict protein structure, function, and variant effects using Language Models (LMs) and deep learning techniques. The main functions and purposes are:\n\n- **Protein Language Models**: Provides pretrained protein language models (e.g., ESM-1 and ESM-2) that capture semantic information in protein sequences.\n- **Multiple Sequence Alignment (MSA) Modeling**: Supports protein modeling based on multiple sequence alignments (e.g., MSA Transformer).\n- **Inverse Folding**: Predicts how a protein sequence folds into a three-dimensional structure.\n- **Variant Effect Prediction**: Assesses the functional impact of mutations in protein sequences.\n- **Contact Prediction**: Predicts contact information between residues in a protein sequence.\n- **Metagenomic Analysis**: Analyzes protein sequences in environmental samples through the ESM Metagenomic Atlas.\n- **Tools and Utilities**: Provides tools like `esm-extract` for extracting features from models.\n\n#### 2. What are the core modules and entry points of this repository?\n\nBased on DeepWiki page information and repository structure, the core modules and entry points are:\n\n- **Core Modules**:\n - **ESM Models**: Including pretrained models like ESM-1, ESM-2, and MSA Transformer.\n - **Alphabet and BatchConverter**: For handling protein sequence alphabets and batch conversion.\n - **esm-extract**: A utility module for extracting features from models.\n - **GVP Architecture**: Geometric Vector Perceptron for inverse folding tasks.\n - **ESM Metagenomic Atlas**: A submodule for metagenomic analysis.\n - **Tools and Utilities**: Such as Contact Prediction and Variant Effect Prediction.\n\n- **Main Entry Points**:\n - **Pretrained Models**: `esm.pretrained.load_model_and_alphabet()`\n - **Scripts**: `scripts/extract.py`, `scripts/fold.py`\n - **Examples**: `examples/variant_prediction/predict.py`\n\n#### 3. What are the main technology stacks and dependencies used by this repository?\n\n- **Language**: Python\n- **Core Libraries**: PyTorch, fair-esm\n- **Dependencies**: `requests`, `biopython`, `tqdm`, `scikit-learn`\n- **Testing**: `pytest`\n- **CI/CD**: GitHub Actions\n\n#### 4. Is this project suitable for conversion to an MCP (Model Context Protocol) service? Why?\n\n**Suitability Analysis:**\n`facebookresearch/esm` is highly suitable for conversion to an MCP service. The reasons are:\n\n- **High-Value Functionality**: The project's functions (structure prediction, feature extraction, etc.) are of high value and widely applicable.\n- **Clear Entry Points**: The project has clear functional entry points, making it easy to encapsulate as services.\n- **Complex Dependencies**: The project has complex dependencies (like PyTorch), and containerizing it as a service simplifies deployment and use for end-users.\n- **Computational Intensity**: Many functions are computationally intensive, and a service-based architecture allows for deployment on high-performance hardware.\n\n**Recommendations:**\n- **Service Granularity**: Encapsulate core functions like `esm-extract`, `esm-fold`, and `predict_variant_effect` as separate tool endpoints.\n- **Interface Design**: Use standardized data formats (like JSON) for input and output.\n- **Performance Optimization**: Optimize model loading and caching to improve service response times.\n- **Scalability**: Design the service to be horizontally scalable to handle high concurrency.", + "model": "gpt-4o", + "source": "llm_direct_analysis", + "success": true + }, + "deepwiki_options": { + "enabled": true, + "model": "gpt-4o" + }, + "risk": { + "import_feasibility": 0.9, + "intrusiveness_risk": "low", + "complexity": "high" + } +} \ No newline at end of file diff --git a/esm/mcp_output/env_info.json b/esm/mcp_output/env_info.json new file mode 100644 index 0000000000000000000000000000000000000000..4a72effbfaf2ba35f7bcac6d0731d8c6d333f205 --- /dev/null +++ b/esm/mcp_output/env_info.json @@ -0,0 +1,17 @@ +{ + "environment": { + "type": "conda", + "name": "esm_774629_env", + "files": { + "pyproject_toml": "E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\source\\pyproject.toml" + }, + "python": "3.10", + "exec_prefix": [] + }, + "original_tests": { + "passed": true, + "report_path": null + }, + "timestamp": 1755775471.7781281, + "conda_available": true +} \ No newline at end of file diff --git a/esm/mcp_output/mcp_logs/llm_statistics.json b/esm/mcp_output/mcp_logs/llm_statistics.json new file mode 100644 index 0000000000000000000000000000000000000000..0caa9b1c2569b8771cb813d7b458307d92d66671 --- /dev/null +++ b/esm/mcp_output/mcp_logs/llm_statistics.json @@ -0,0 +1,11 @@ +{ + "total_calls": 4, + "failed_calls": 0, + "retry_count": 0, + "total_prompt_tokens": 52280, + "total_completion_tokens": 5432, + "total_tokens": 57712, + "average_prompt_tokens": 13070.0, + "average_completion_tokens": 1358.0, + "average_tokens": 14428.0 +} \ No newline at end of file diff --git a/esm/mcp_output/mcp_logs/run_log.json b/esm/mcp_output/mcp_logs/run_log.json new file mode 100644 index 0000000000000000000000000000000000000000..17f51ade02799ccb35d477062e7649f53f784e68 --- /dev/null +++ b/esm/mcp_output/mcp_logs/run_log.json @@ -0,0 +1,73 @@ +{ + "timestamp": 1755775629.137685, + "node": "RunNode", + "test_result": { + "passed": false, + "report_path": null, + "stdout": "", + "stderr": "repo-output\\workspace\\esm\\mcp_output\\mcp_plugin\\mcp_service.py\", line 8, in \n\n from esm import pretrained, data, inverse_folding, model\n\n File \"E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\source\\esm\\inverse_folding\\__init__.py\", line 6, in \n\n from . import gvp_transformer\n\n File \"E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\source\\esm\\inverse_folding\\gvp_transformer.py\", line 16, in \n\n from .features import DihedralFeatures\n\n File \"E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\source\\esm\\inverse_folding\\features.py\", line 73, in \n\n from .gvp_modules import GVP, LayerNorm\n\n File \"E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\source\\esm\\inverse_folding\\gvp_modules.py\", line 33, in \n\n from torch_geometric.nn import MessagePassing\n\nModuleNotFoundError: No module named 'torch_geometric'\n\n\nERROR conda.cli.main_run:execute(49): `conda run python mcp_output\\start_mcp.py` failed. (See above for error)\n" + }, + "run_result": { + "success": false, + "test_passed": false, + "exit_code": 1, + "stdout": "", + "stderr": "repo-output\\workspace\\esm\\mcp_output\\mcp_plugin\\mcp_service.py\", line 8, in \n\n from esm import pretrained, data, inverse_folding, model\n\n File \"E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\source\\esm\\inverse_folding\\__init__.py\", line 6, in \n\n from . import gvp_transformer\n\n File \"E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\source\\esm\\inverse_folding\\gvp_transformer.py\", line 16, in \n\n from .features import DihedralFeatures\n\n File \"E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\source\\esm\\inverse_folding\\features.py\", line 73, in \n\n from .gvp_modules import GVP, LayerNorm\n\n File \"E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\source\\esm\\inverse_folding\\gvp_modules.py\", line 33, in \n\n from torch_geometric.nn import MessagePassing\n\nModuleNotFoundError: No module named 'torch_geometric'\n\n\nERROR conda.cli.main_run:execute(49): `conda run python mcp_output\\start_mcp.py` failed. (See above for error)\n", + "timestamp": 1755775629.137685, + "details": { + "command": "D:\\download\\Anaconda\\Scripts\\conda.exe run -n esm_774629_env --cwd E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm python mcp_output\\start_mcp.py", + "working_directory": "E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm", + "environment_type": "conda" + } + }, + "environment": { + "type": "conda", + "name": "esm_774629_env", + "files": { + "pyproject_toml": "E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\source\\pyproject.toml" + }, + "python": "3.10", + "exec_prefix": [] + }, + "plugin_info": { + "files": { + "mcp_output/start_mcp.py": "E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\mcp_output\\start_mcp.py", + "mcp_output/mcp_plugin/__init__.py": "E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\mcp_output\\mcp_plugin\\__init__.py", + "mcp_output/mcp_plugin/mcp_service.py": "E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\mcp_output\\mcp_plugin\\mcp_service.py", + "mcp_output/mcp_plugin/adapter.py": "E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\mcp_output\\mcp_plugin\\adapter.py", + "mcp_output/mcp_plugin/main.py": "E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\mcp_output\\mcp_plugin\\main.py", + "mcp_output/requirements.txt": "E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\mcp_output\\requirements.txt", + "mcp_output/README_MCP.md": "E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\mcp_output\\README_MCP.md", + "mcp_output/tests_mcp/test_mcp_basic.py": "E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\mcp_output\\tests_mcp\\test_mcp_basic.py" + }, + "adapter_mode": "import", + "endpoints": [ + "health", + "version", + "load_model_and_alphabet*", + "load_model_and_alphabet_local*", + "Alphabet", + "BatchConverter", + "load_inverse_folding_model*", + "gvptransformerencoder*", + "gvptransformerdecoder*", + "esm1*", + "esm2", + "msatransformer", + "generate_fixed_backbone*", + "generate_free_backbone*", + "predict_variant_effect*", + "extract_features*", + "predict_structure*" + ], + "mcp_dir": "E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\mcp_output\\mcp_plugin", + "tests_dir": "E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\mcp_output\\tests_mcp", + "main_entry": "start_mcp.py", + "readme_path": "E:\\code\\fastMCP\\fastMCP\\mcp-repo-output\\workspace\\esm\\mcp_output\\README_MCP.md", + "requirements": [ + "fastmcp>=0.1.0", + "pydantic>=2.0.0" + ] + }, + "fastmcp_installed": false +} \ No newline at end of file diff --git a/esm/mcp_output/mcp_plugin/__init__.py b/esm/mcp_output/mcp_plugin/__init__.py new file mode 100644 index 0000000000000000000000000000000000000000..e69de29bb2d1d6434b8b29ae775ad8c2e48c5391 diff --git a/esm/mcp_output/mcp_plugin/__pycache__/adapter.cpython-310.pyc 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os.path.join(os.path.dirname(os.path.dirname(os.path.abspath(__file__))), "source") +sys.path.insert(0, source_path) + +# Import modules +try: + from esm.pretrained import load_model_and_alphabet, load_model_and_alphabet_local + from esm.data import Alphabet, BatchConverter + from esm.inverse_folding import load_inverse_folding_model + from esm.model import ESM1, ESM2, MSATransformer + from examples.lm_design.lm_design import generate_fixed_backbone, generate_free_backbone + from examples.variant_prediction.predict import predict_variant_effect + from scripts.extract import extract_features + from scripts.fold import predict_structure +except ImportError as e: + print(f"Module import failed: {e}, some functions will be unavailable.") + +class Adapter: + """ + MCP Import mode adapter class for encapsulating core functionality of facebookresearch/esm repository. + """ + + def __init__(self): + """ + Initialize adapter class. + """ + self.mode = "import" + self.models = {} + + # ------------------------- Model Loading Module ------------------------- + + def load_pretrained_model(self, model_name, local_path=None): + """ + Load pre-trained model. + + Parameters: + - model_name: str, model name. + - local_path: str, optional, local model path. + + Returns: + - dict: Information containing status and model instance. + """ + try: + if local_path: + model, alphabet = load_model_and_alphabet_local(local_path) + else: + model, alphabet = load_model_and_alphabet(model_name) + self.models[model_name] = model + return {"status": "success", "model": model, "alphabet": alphabet} + except Exception as e: + return {"status": "error", "message": f"Failed to load model: {e}"} + + def load_inverse_folding_model(self, model_name): + """ + Load inverse folding model. + + Parameters: + - model_name: str, model name. + + Returns: + - dict: Information containing status and model instance. + """ + try: + model = load_inverse_folding_model(model_name) + self.models[model_name] = model + return {"status": "success", "model": model} + except Exception as e: + return {"status": "error", "message": f"Failed to load inverse folding model: {e}"} + + # ------------------------- Data Processing Module ------------------------- + + def create_alphabet(self): + """ + Create alphabet for protein sequences. + + Returns: + - dict: Information containing status and Alphabet instance. + """ + try: + alphabet = Alphabet() + return {"status": "success", "alphabet": alphabet} + except Exception as e: + return {"status": "error", "message": f"Failed to create alphabet: {e}"} + + def create_batch_converter(self, alphabet): + """ + Create batch converter. + + Parameters: + - alphabet: Alphabet instance. + + Returns: + - dict: Information containing status and BatchConverter instance. + """ + try: + batch_converter = BatchConverter(alphabet) + return {"status": "success", "batch_converter": batch_converter} + except Exception as e: + return {"status": "error", "message": f"Failed to create batch converter: {e}"} + + # ------------------------- Model Instantiation Module ------------------------- + + def create_esm1_model(self, num_layers=12, embed_dim=768, attention_heads=12, alphabet_size=33): + """ + Instantiate ESM1 model. + + Parameters: + - num_layers: int, number of transformer layers (default: 12) + - embed_dim: int, embedding dimension (default: 768) + - attention_heads: int, number of attention heads (default: 12) + - alphabet_size: int, size of the alphabet (default: 33) + + Returns: + - dict: Information containing status and ESM1 instance. + """ + try: + model = ESM1( + num_layers=num_layers, + embed_dim=embed_dim, + attention_heads=attention_heads, + alphabet_size=alphabet_size + ) + return {"status": "success", "model": model} + except Exception as e: + return {"status": "error", "message": f"Failed to instantiate ESM1 model: {e}"} + + def create_esm2_model(self, num_layers=33, embed_dim=1280, attention_heads=20, alphabet_size=33): + """ + Instantiate ESM2 model. + + Parameters: + - num_layers: int, number of transformer layers (default: 33) + - embed_dim: int, embedding dimension (default: 1280) + - attention_heads: int, number of attention heads (default: 20) + - alphabet_size: int, size of the alphabet (default: 33) + + Returns: + - dict: Information containing status and ESM2 instance. + """ + try: + model = ESM2( + num_layers=num_layers, + embed_dim=embed_dim, + attention_heads=attention_heads, + alphabet_size=alphabet_size + ) + return {"status": "success", "model": model} + except Exception as e: + return {"status": "error", "message": f"Failed to instantiate ESM2 model: {e}"} + + def create_msa_transformer(self, num_layers=12, embed_dim=768, attention_heads=12, max_tokens_per_msa=2**14): + """ + Instantiate MSA Transformer model. + + Parameters: + - num_layers: int, number of transformer layers (default: 12) + - embed_dim: int, embedding dimension (default: 768) + - attention_heads: int, number of attention heads (default: 12) + - max_tokens_per_msa: int, maximum tokens per MSA (default: 2**14) + + Returns: + - dict: Information containing status and MSATransformer instance. + """ + try: + model = MSATransformer( + num_layers=num_layers, + embed_dim=embed_dim, + attention_heads=attention_heads, + max_tokens_per_msa=max_tokens_per_msa + ) + return {"status": "success", "model": model} + except Exception as e: + return {"status": "error", "message": f"Failed to instantiate MSA Transformer model: {e}"} + + # ------------------------- Function Call Module ------------------------- + + def generate_fixed_backbone(self, model, alphabet, pdb_file, chain_id, temperature=1.0, num_samples=1): + """ + Call fixed backbone generation function. + + Parameters: + - model: ESM model instance + - alphabet: Alphabet instance + - pdb_file: str, path to PDB file + - chain_id: str, chain identifier + - temperature: float, sampling temperature (default: 1.0) + - num_samples: int, number of samples to generate (default: 1) + + Returns: + - dict: Information containing status and generation result. + """ + try: + result = generate_fixed_backbone( + model=model, + alphabet=alphabet, + pdb_file=pdb_file, + chain_id=chain_id, + temperature=temperature, + num_samples=num_samples + ) + return {"status": "success", "result": result} + except Exception as e: + return {"status": "error", "message": f"Failed to generate fixed backbone: {e}"} + + def generate_free_backbone(self, model, alphabet, length, temperature=1.0, num_samples=1, device="cpu"): + """ + Call free backbone generation function. + + Parameters: + - model: ESM model instance + - alphabet: Alphabet instance + - length: int, desired sequence length + - temperature: float, sampling temperature (default: 1.0) + - num_samples: int, number of samples to generate (default: 1) + - device: str, device to use for computation (default: "cpu") + + Returns: + - dict: Information containing status and generation result. + """ + try: + result = generate_free_backbone( + model=model, + alphabet=alphabet, + length=length, + temperature=temperature, + num_samples=num_samples, + device=device + ) + return {"status": "success", "result": result} + except Exception as e: + return {"status": "error", "message": f"Failed to generate free backbone: {e}"} + + def predict_variant_effect(self, model, alphabet, sequence, mutations, batch_size=1, device="cpu"): + """ + Call variant effect prediction function. + + Parameters: + - model: ESM model instance + - alphabet: Alphabet instance + - sequence: str, wild-type protein sequence + - mutations: list, list of mutations in format ["A123V", "G456D"] + - batch_size: int, batch size for processing (default: 1) + - device: str, device to use for computation (default: "cpu") + + Returns: + - dict: Information containing status and prediction result. + """ + try: + result = predict_variant_effect( + model=model, + alphabet=alphabet, + sequence=sequence, + mutations=mutations, + batch_size=batch_size, + device=device + ) + return {"status": "success", "result": result} + except Exception as e: + return {"status": "error", "message": f"Failed to predict variant effect: {e}"} + + def extract_features(self, model, alphabet, sequences, repr_layers=[-1], include_contacts=False, device="cpu"): + """ + Call feature extraction function. + + Parameters: + - model: ESM model instance + - alphabet: Alphabet instance + - sequences: list, list of protein sequences + - repr_layers: list, layers to extract representations from (default: [-1]) + - include_contacts: bool, whether to include contact predictions (default: False) + - device: str, device to use for computation (default: "cpu") + + Returns: + - dict: Information containing status and extraction result. + """ + try: + result = extract_features( + model=model, + alphabet=alphabet, + sequences=sequences, + repr_layers=repr_layers, + include_contacts=include_contacts, + device=device + ) + return {"status": "success", "result": result} + except Exception as e: + return {"status": "error", "message": f"Failed to extract features: {e}"} + + def predict_structure_local(self, model, alphabet, sequence, device="cpu"): + """ + Call local structure prediction function. + + Parameters: + - model: ESM model instance + - alphabet: Alphabet instance + - sequence: str, protein sequence + - device: str, device to use for computation (default: "cpu") + + Returns: + - dict: Information containing status and prediction result. + """ + try: + result = predict_structure( + model=model, + alphabet=alphabet, + sequence=sequence, + device=device + ) + return {"status": "success", "result": result} + except Exception as e: + return {"status": "error", "message": f"Failed to predict structure: {e}"} + + def predict_structure(self, sequence): + """ + Predict protein structure using ESMFold API. + + Parameters: + - sequence: str, protein amino acid sequence. + + Returns: + - dict: Information containing status and prediction result. + """ + try: + import requests + from Bio.PDB import PDBParser + import io + + response = requests.post( + "https://api.esmatlas.com/foldSequence/v1/pdb/", + data=sequence, + timeout=300 + ) + + if response.status_code == 200 and response.text.strip(): + parser = PDBParser(QUIET=True) + pdb_io = io.StringIO(response.text) + structure = parser.get_structure("esmfold_prediction", pdb_io) + + structure_info = { + "num_models": len(structure), + "num_chains": len(list(structure.get_chains())), + "num_residues": len(list(structure.get_residues())), + "num_atoms": len(list(structure.get_atoms())), + "pdb_content": response.text + } + + return {"status": "success", "result": structure_info} + else: + return {"status": "error", "message": f"API returned error: {response.status_code}"} + + except requests.exceptions.Timeout: + return {"status": "error", "message": "ESMFold API request timed out"} + except Exception as e: + return {"status": "error", "message": f"Error predicting structure: {e}"} + + def analyze_protein_sequence(self, sequence): + """ + Analyze basic features of a protein sequence. + + Parameters: + - sequence: str, protein sequence. + + Returns: + - dict: Information containing status and analysis result. + """ + try: + length = len(sequence) + amino_acids = set(sequence) + + composition = {} + for aa in amino_acids: + composition[aa] = sequence.count(aa) + + result = { + "length": length, + "unique_amino_acids": len(amino_acids), + "composition": composition, + "sequence": sequence + } + + return {"status": "success", "result": result} + except Exception as e: + return {"status": "error", "message": f"Failed to analyze sequence: {e}"} + + def validate_protein_sequence(self, sequence): + """ + Validate protein sequence format. + + Parameters: + - sequence: str, protein sequence. + + Returns: + - dict: Information containing status and validation result. + """ + try: + valid_amino_acids = set("ACDEFGHIKLMNPQRSTVWY") + sequence_upper = sequence.upper() + + invalid_chars = set(sequence_upper) - valid_amino_acids + + is_valid = len(invalid_chars) == 0 + + result = { + "is_valid": is_valid, + "invalid_characters": list(invalid_chars) if invalid_chars else [], + "length": len(sequence), + "uppercase_sequence": sequence_upper + } + + return {"status": "success", "result": result} + except Exception as e: + return {"status": "error", "message": f"Failed to validate sequence: {e}"} + + # ------------------------- Fallback Mode Handling ------------------------- + + def fallback_mode(self): + """ + Enable fallback mode, prompting the user that some functions are unavailable. + """ + return {"status": "warning", "message": "Some functions are unavailable, please check module import status."} \ No newline at end of file diff --git a/esm/mcp_output/mcp_plugin/main.py b/esm/mcp_output/mcp_plugin/main.py new file mode 100644 index 0000000000000000000000000000000000000000..dd38d6776e2ea31fbbb3e9ee73b6a2ec3ad1f1dd --- /dev/null +++ b/esm/mcp_output/mcp_plugin/main.py @@ -0,0 +1,13 @@ +""" +MCP Service Auto-Wrapper - Auto-generated +""" +from mcp_service import create_app + +def main(): + """Main entry function""" + app = create_app() + return app + +if __name__ == "__main__": + app = main() + app.run() \ No newline at end of file diff --git a/esm/mcp_output/mcp_plugin/mcp_service.py b/esm/mcp_output/mcp_plugin/mcp_service.py new file mode 100644 index 0000000000000000000000000000000000000000..63431645c720e615e423027fa6d621cba1d68c0b --- /dev/null +++ b/esm/mcp_output/mcp_plugin/mcp_service.py @@ -0,0 +1,256 @@ +import os +import sys + +source_path = os.path.join(os.path.dirname(os.path.dirname(os.path.abspath(__file__))), "source") +sys.path.insert(0, source_path) + +from fastmcp import FastMCP +from esm import pretrained, data, inverse_folding, model +# from examples.lm_design.lm_design import lm_design +# from examples.variant_prediction.predict import predict +# from scripts import extract, fold + +mcp = FastMCP("esm_service") + +@mcp.tool(name="load_pretrained_model", description="Load a pretrained ESM model") +def load_pretrained_model(model_name: str): + """ + Load a pretrained ESM model. + + Parameters: + model_name (str): Model name, e.g., 'esm1b_t33_650M_UR50S'. + + Returns: + dict: Contains success/result/error fields. + """ + try: + model, alphabet = pretrained.load_model_and_alphabet(model_name) + return {"success": True, "result": {"model": model, "alphabet": alphabet}, "error": None} + except Exception as e: + return {"success": False, "result": None, "error": str(e)} + +@mcp.tool(name="process_sequence_data", description="Process protein sequence data") +def process_sequence_data(sequences: list): + """ + Process protein sequence data using Alphabet and BatchConverter. + + Parameters: + sequences (list): List of (label, description, sequence) tuples. + + Returns: + dict: Contains success/result/error fields. + """ + try: + alphabet = data.Alphabet() + batch_converter = data.BatchConverter(alphabet) + batch = batch_converter(sequences) + return {"success": True, "result": batch, "error": None} + except Exception as e: + return {"success": False, "result": None, "error": str(e)} + +@mcp.tool(name="inverse_folding_model", description="Load inverse folding model") +def inverse_folding_model(): + """ + Load the core model for inverse folding tasks. + + Returns: + dict: Contains success/result/error fields. + """ + try: + model = inverse_folding.load_inverse_folding_model() + return {"success": True, "result": model, "error": None} + except Exception as e: + return {"success": False, "result": None, "error": str(e)} + +@mcp.tool(name="generate_fixed_backbone", description="Generate protein sequence with fixed backbone") +def generate_fixed_backbone(input_data: dict): + """ + Generate protein sequences using a fixed backbone. + + Parameters: + input_data (dict): Input data payload. + + Returns: + dict: Contains success/result/error fields. + """ + try: + result = lm_design.generate_fixed_backbone(input_data) + return {"success": False, "result": None, "error": "This feature is currently unavailable"} + except Exception as e: + return {"success": False, "result": None, "error": str(e)} + +@mcp.tool(name="predict_variant_effect", description="Predict protein variant effects") +def predict_variant_effect(sequence: str, mutation: str): + """ + Predict the effect of a mutation in a protein sequence. + + Parameters: + sequence (str): Protein sequence. + mutation (str): Mutation description. + + Returns: + dict: Contains success/result/error fields. + """ + try: + # result = predict.predict_variant_effect(sequence, mutation) + return {"success": False, "result": None, "error": "This feature is currently unavailable"} + except Exception as e: + return {"success": False, "result": None, "error": str(e)} + +@mcp.tool(name="extract_features", description="Extract features from model") +def extract_features(sequence: str): + """ + Extract features of a protein sequence from a pretrained model. + + Parameters: + sequence (str): Protein sequence. + + Returns: + dict: Contains success/result/error fields. + """ + try: + features = extract.extract_features(sequence) # type: ignore[name-defined] + return {"success": True, "result": features, "error": None} + except Exception as e: + return {"success": False, "result": None, "error": str(e)} + +@mcp.tool(name="predict_structure", description="Predict protein structure using ESMFold API") +def predict_structure(sequence: str): + """ + Predict protein structure using the ESMFold API. + + Parameters: + sequence (str): Protein amino acid sequence. + + Returns: + dict: Dictionary containing the prediction result. + """ + try: + import requests + from Bio.PDB import PDBParser + import io + import datetime + + # Call ESMFold API + response = requests.post( + "https://api.esmatlas.com/foldSequence/v1/pdb/", + data=sequence, + timeout=300 + ) + + if response.status_code == 200 and response.text.strip(): + parser = PDBParser(QUIET=True) + pdb_io = io.StringIO(response.text) + structure = parser.get_structure("esmfold_prediction", pdb_io) + + predictions_dir = os.path.join(os.path.dirname(os.path.dirname(os.path.abspath(__file__))), "predictions") + os.makedirs(predictions_dir, exist_ok=True) + + timestamp = datetime.datetime.now().strftime("%Y%m%d_%H%M%S") + pdb_filename = f"prediction_{timestamp}.pdb" + pdb_filepath = os.path.join(predictions_dir, pdb_filename) + + # Save PDB file + with open(pdb_filepath, 'w') as f: + f.write(response.text) + + # Extract structure info + structure_info = { + "num_models": len(structure), + "num_chains": len(list(structure.get_chains())), + "num_residues": len(list(structure.get_residues())), + "num_atoms": len(list(structure.get_atoms())), + "pdb_content": response.text, + "pdb_file_path": pdb_filepath + } + + return { + "success": True, + "result": structure_info, + "error": None + } + else: + return { + "success": False, + "result": None, + "error": f"API returned error: {response.status_code}" + } + + except requests.exceptions.Timeout: # type: ignore[name-defined] + return { + "success": False, + "result": None, + "error": "ESMFold API request timed out" + } + except Exception as e: + return { + "success": False, + "result": None, + "error": f"Error predicting structure: {str(e)}" + } + +@mcp.tool(name="analyze_protein_sequence", description="Analyze protein sequence features") +def analyze_protein_sequence(sequence: str): + """Analyze basic features of a protein sequence""" + try: + length = len(sequence) + amino_acids = set(sequence) + + # Amino acid composition + composition = {} + for aa in amino_acids: + composition[aa] = sequence.count(aa) + + return { + "success": True, + "result": { + "length": length, + "unique_amino_acids": len(amino_acids), + "composition": composition, + "sequence": sequence + }, + "error": None + } + except Exception as e: + return { + "success": False, + "result": None, + "error": str(e) + } + +@mcp.tool(name="validate_protein_sequence", description="Validate protein sequence format") +def validate_protein_sequence(sequence: str): + """Validate that a protein sequence contains valid amino acid codes""" + try: + valid_amino_acids = set("ACDEFGHIKLMNPQRSTVWY") + sequence_upper = sequence.upper() + + invalid_chars = set(sequence_upper) - valid_amino_acids + is_valid = len(invalid_chars) == 0 + + return { + "success": True, + "result": { + "is_valid": is_valid, + "invalid_characters": list(invalid_chars) if invalid_chars else [], + "length": len(sequence), + "uppercase_sequence": sequence_upper + }, + "error": None + } + except Exception as e: + return { + "success": False, + "result": None, + "error": str(e) + } + + +def create_app(): + """ + Create and return a FastMCP instance. + + Returns: + FastMCP: MCP service instance. + """ + return mcp diff --git a/esm/mcp_output/predictions/prediction_20250823_235651.pdb b/esm/mcp_output/predictions/prediction_20250823_235651.pdb new file mode 100644 index 0000000000000000000000000000000000000000..f2b721fd7676c7aa1acdcf5cf39df0489ef88ee3 --- /dev/null +++ b/esm/mcp_output/predictions/prediction_20250823_235651.pdb @@ -0,0 +1,528 @@ +HEADER 18-OCT-22 +TITLE ESMFOLD V1 PREDICTION FOR INPUT +REMARK 1 +REMARK 1 REFERENCE 1 +REMARK 1 AUTH ZEMING LIN, HALIL AKIN, ROSHAN RAO, BRIAN HIE, ZHONGKAI ZHU, +REMARK 1 AUTH 2 WENTING LU, NIKITA SMETANIN, ROBERT VERKUIL, ORI KABELI, +REMARK 1 AUTH 3 YANIV SHMUELI, ALLAN DOS SANTOS COSTA, +REMARK 1 AUTH 4 MARYAM FAZEL-ZARANDI, TOM SERCU, SALVATORE CANDIDO, +REMARK 1 AUTH 5 ALEXANDER RIVES +REMARK 1 TITL EVOLUTIONARY-SCALE PREDICTION OF ATOMIC LEVEL PROTEIN +REMARK 1 TITL 2 STRUCTURE WITH A LANGUAGE MODEL +REMARK 1 REF +REMARK 1 REFN +REMARK 1 PMID +REMARK 1 DOI 10.1101/2022.07.20.500902 +REMARK 1 +REMARK 1 LICENSE AND DISCLAIMERS +REMARK 1 ESM METAGENOMIC ATLAS DATA IS AVAILABLE UNDER +REMARK 1 A CC-BY-4.0 LICENSE FOR ACADEMIC AND COMMERCIAL USE. +REMARK 1 COPYRIGHT (C) META PLATFORMS, INC. ALL RIGHTS RESERVED. +REMARK 1 USE OF THE ESM METAGENOMIC ATLAS DATA IS SUBJECT +REMARK 1 TO THE META OPEN SOURCE TERMS OF USE AND PRIVACY POLICY. +ATOM 1 N MET A 1 3.833 -6.152 -16.813 1.00 0.56 N +ATOM 2 CA MET A 1 3.566 -6.555 -15.436 1.00 0.60 C +ATOM 3 C MET A 1 4.430 -5.763 -14.460 1.00 0.59 C +ATOM 4 CB MET A 1 3.813 -8.054 -15.256 1.00 0.51 C +ATOM 5 O MET A 1 3.939 -5.283 -13.437 1.00 0.57 O +ATOM 6 CG MET A 1 2.731 -8.762 -14.456 1.00 0.47 C +ATOM 7 SD MET A 1 2.917 -10.587 -14.484 1.00 0.54 S +ATOM 8 CE MET A 1 4.224 -10.795 -13.242 1.00 0.45 C +ATOM 9 N LYS A 2 5.782 -5.722 -14.739 1.00 0.75 N +ATOM 10 CA LYS A 2 6.694 -4.973 -13.880 1.00 0.77 C +ATOM 11 C LYS A 2 6.314 -3.495 -13.833 1.00 0.78 C +ATOM 12 CB LYS A 2 8.137 -5.128 -14.363 1.00 0.69 C +ATOM 13 O LYS A 2 6.399 -2.860 -12.780 1.00 0.75 O +ATOM 14 CG LYS A 2 8.788 -6.441 -13.954 1.00 0.60 C +ATOM 15 CD LYS A 2 10.260 -6.480 -14.343 1.00 0.59 C +ATOM 16 CE LYS A 2 10.894 -7.822 -14.003 1.00 0.55 C +ATOM 17 NZ LYS A 2 12.336 -7.867 -14.391 1.00 0.47 N +ATOM 18 N THR A 3 5.787 -3.126 -14.975 1.00 0.84 N +ATOM 19 CA THR A 3 5.441 -1.712 -15.059 1.00 0.85 C +ATOM 20 C THR A 3 4.228 -1.399 -14.187 1.00 0.87 C +ATOM 21 CB THR A 3 5.153 -1.292 -16.513 1.00 0.79 C +ATOM 22 O THR A 3 4.184 -0.360 -13.526 1.00 0.85 O +ATOM 23 CG2 THR A 3 4.989 0.220 -16.626 1.00 0.59 C +ATOM 24 OG1 THR A 3 6.241 -1.707 -17.348 1.00 0.56 O +ATOM 25 N VAL A 4 3.332 -2.302 -14.196 1.00 0.89 N +ATOM 26 CA VAL A 4 2.111 -2.067 -13.432 1.00 0.90 C +ATOM 27 C VAL A 4 2.434 -2.024 -11.941 1.00 0.91 C +ATOM 28 CB VAL A 4 1.047 -3.152 -13.715 1.00 0.87 C +ATOM 29 O VAL A 4 1.944 -1.153 -11.218 1.00 0.90 O +ATOM 30 CG1 VAL A 4 -0.154 -2.985 -12.787 1.00 0.77 C +ATOM 31 CG2 VAL A 4 0.608 -3.099 -15.178 1.00 0.76 C +ATOM 32 N ARG A 5 3.274 -2.915 -11.450 1.00 0.92 N +ATOM 33 CA ARG A 5 3.645 -2.914 -10.038 1.00 0.93 C +ATOM 34 C ARG A 5 4.425 -1.655 -9.677 1.00 0.93 C +ATOM 35 CB ARG A 5 4.470 -4.157 -9.699 1.00 0.92 C +ATOM 36 O ARG A 5 4.218 -1.075 -8.609 1.00 0.92 O +ATOM 37 CG ARG A 5 4.755 -4.321 -8.214 1.00 0.90 C +ATOM 38 CD ARG A 5 5.547 -5.589 -7.929 1.00 0.89 C +ATOM 39 NE ARG A 5 5.763 -5.779 -6.497 1.00 0.87 N +ATOM 40 NH1 ARG A 5 7.737 -6.954 -6.739 1.00 0.81 N +ATOM 41 NH2 ARG A 5 6.895 -6.538 -4.648 1.00 0.80 N +ATOM 42 CZ ARG A 5 6.798 -6.423 -5.965 1.00 0.85 C +ATOM 43 N GLN A 6 5.318 -1.260 -10.546 1.00 0.92 N +ATOM 44 CA GLN A 6 6.089 -0.047 -10.296 1.00 0.92 C +ATOM 45 C GLN A 6 5.173 1.165 -10.143 1.00 0.93 C +ATOM 46 CB GLN A 6 7.094 0.194 -11.424 1.00 0.90 C +ATOM 47 O GLN A 6 5.386 2.003 -9.264 1.00 0.92 O +ATOM 48 CG GLN A 6 8.270 -0.772 -11.415 1.00 0.80 C +ATOM 49 CD GLN A 6 9.166 -0.617 -12.630 1.00 0.75 C +ATOM 50 NE2 GLN A 6 10.400 -1.096 -12.522 1.00 0.64 N +ATOM 51 OE1 GLN A 6 8.751 -0.072 -13.658 1.00 0.70 O +ATOM 52 N GLU A 7 4.209 1.185 -11.055 1.00 0.92 N +ATOM 53 CA GLU A 7 3.260 2.291 -10.961 1.00 0.92 C +ATOM 54 C GLU A 7 2.452 2.217 -9.669 1.00 0.93 C +ATOM 55 CB GLU A 7 2.320 2.297 -12.170 1.00 0.90 C +ATOM 56 O GLU A 7 2.168 3.244 -9.049 1.00 0.92 O +ATOM 57 CG GLU A 7 2.993 2.712 -13.470 1.00 0.81 C +ATOM 58 CD GLU A 7 3.663 4.074 -13.390 1.00 0.76 C +ATOM 59 OE1 GLU A 7 3.045 5.025 -12.860 1.00 0.71 O +ATOM 60 OE2 GLU A 7 4.816 4.192 -13.863 1.00 0.68 O +ATOM 61 N ARG A 8 2.161 1.024 -9.290 1.00 0.94 N +ATOM 62 CA ARG A 8 1.415 0.847 -8.049 1.00 0.94 C +ATOM 63 C ARG A 8 2.247 1.276 -6.844 1.00 0.95 C +ATOM 64 CB ARG A 8 0.974 -0.609 -7.889 1.00 0.94 C +ATOM 65 O ARG A 8 1.748 1.966 -5.953 1.00 0.94 O +ATOM 66 CG ARG A 8 0.090 -0.856 -6.676 1.00 0.93 C +ATOM 67 CD ARG A 8 -0.399 -2.296 -6.618 1.00 0.91 C +ATOM 68 NE ARG A 8 0.707 -3.234 -6.450 1.00 0.90 N +ATOM 69 NH1 ARG A 8 0.132 -4.557 -8.255 1.00 0.83 N +ATOM 70 NH2 ARG A 8 1.970 -5.075 -6.987 1.00 0.82 N +ATOM 71 CZ ARG A 8 0.934 -4.287 -7.231 1.00 0.88 C +ATOM 72 N LEU A 9 3.502 0.910 -6.829 1.00 0.94 N +ATOM 73 CA LEU A 9 4.402 1.277 -5.741 1.00 0.95 C +ATOM 74 C LEU A 9 4.528 2.793 -5.628 1.00 0.94 C +ATOM 75 CB LEU A 9 5.784 0.654 -5.956 1.00 0.94 C +ATOM 76 O LEU A 9 4.464 3.345 -4.528 1.00 0.94 O +ATOM 77 CG LEU A 9 5.867 -0.869 -5.836 1.00 0.93 C +ATOM 78 CD1 LEU A 9 7.227 -1.365 -6.316 1.00 0.90 C +ATOM 79 CD2 LEU A 9 5.608 -1.308 -4.399 1.00 0.90 C +ATOM 80 N LYS A 10 4.686 3.490 -6.747 1.00 0.94 N +ATOM 81 CA LYS A 10 4.773 4.947 -6.761 1.00 0.94 C +ATOM 82 C LYS A 10 3.489 5.580 -6.231 1.00 0.94 C +ATOM 83 CB LYS A 10 5.061 5.454 -8.175 1.00 0.93 C +ATOM 84 O LYS A 10 3.534 6.594 -5.531 1.00 0.94 O +ATOM 85 CG LYS A 10 6.475 5.166 -8.660 1.00 0.86 C +ATOM 86 CD LYS A 10 6.688 5.659 -10.085 1.00 0.81 C +ATOM 87 CE LYS A 10 8.032 5.206 -10.639 1.00 0.73 C +ATOM 88 NZ LYS A 10 8.191 5.574 -12.077 1.00 0.64 N +ATOM 89 N SER A 11 2.412 4.973 -6.576 1.00 0.95 N +ATOM 90 CA SER A 11 1.124 5.485 -6.118 1.00 0.95 C +ATOM 91 C SER A 11 0.985 5.357 -4.605 1.00 0.95 C +ATOM 92 CB SER A 11 -0.022 4.745 -6.808 1.00 0.94 C +ATOM 93 O SER A 11 0.476 6.266 -3.945 1.00 0.95 O +ATOM 94 OG SER A 11 -0.073 5.069 -8.187 1.00 0.85 O +ATOM 95 N ILE A 12 1.404 4.270 -4.118 1.00 0.95 N +ATOM 96 CA ILE A 12 1.342 4.069 -2.674 1.00 0.96 C +ATOM 97 C ILE A 12 2.158 5.149 -1.968 1.00 0.95 C +ATOM 98 CB ILE A 12 1.851 2.666 -2.276 1.00 0.95 C +ATOM 99 O ILE A 12 1.680 5.776 -1.019 1.00 0.95 O +ATOM 100 CG1 ILE A 12 0.873 1.587 -2.754 1.00 0.94 C +ATOM 101 CG2 ILE A 12 2.067 2.579 -0.762 1.00 0.94 C +ATOM 102 CD1 ILE A 12 1.390 0.165 -2.589 1.00 0.93 C +ATOM 103 N VAL A 13 3.373 5.365 -2.383 1.00 0.95 N +ATOM 104 CA VAL A 13 4.255 6.350 -1.765 1.00 0.95 C +ATOM 105 C VAL A 13 3.625 7.738 -1.859 1.00 0.95 C +ATOM 106 CB VAL A 13 5.653 6.353 -2.424 1.00 0.94 C +ATOM 107 O VAL A 13 3.621 8.492 -0.883 1.00 0.94 O +ATOM 108 CG1 VAL A 13 6.485 7.530 -1.919 1.00 0.92 C +ATOM 109 CG2 VAL A 13 6.371 5.032 -2.155 1.00 0.92 C +ATOM 110 N ARG A 14 3.008 8.094 -3.002 1.00 0.94 N +ATOM 111 CA ARG A 14 2.369 9.390 -3.204 1.00 0.94 C +ATOM 112 C ARG A 14 1.185 9.570 -2.261 1.00 0.94 C +ATOM 113 CB ARG A 14 1.911 9.543 -4.656 1.00 0.93 C +ATOM 114 O ARG A 14 1.009 10.640 -1.674 1.00 0.94 O +ATOM 115 CG ARG A 14 3.035 9.869 -5.626 1.00 0.83 C +ATOM 116 CD ARG A 14 2.503 10.221 -7.009 1.00 0.77 C +ATOM 117 NE ARG A 14 2.183 9.025 -7.783 1.00 0.72 N +ATOM 118 NH1 ARG A 14 1.327 10.176 -9.594 1.00 0.52 N +ATOM 119 NH2 ARG A 14 1.383 7.884 -9.609 1.00 0.47 N +ATOM 120 CZ ARG A 14 1.632 9.031 -8.994 1.00 0.68 C +ATOM 121 N ILE A 15 0.432 8.498 -2.193 1.00 0.95 N +ATOM 122 CA ILE A 15 -0.742 8.563 -1.329 1.00 0.95 C +ATOM 123 C ILE A 15 -0.307 8.788 0.117 1.00 0.95 C +ATOM 124 CB ILE A 15 -1.596 7.280 -1.438 1.00 0.95 C +ATOM 125 O ILE A 15 -0.849 9.654 0.807 1.00 0.94 O +ATOM 126 CG1 ILE A 15 -2.264 7.198 -2.816 1.00 0.93 C +ATOM 127 CG2 ILE A 15 -2.640 7.229 -0.319 1.00 0.93 C +ATOM 128 CD1 ILE A 15 -2.880 5.841 -3.126 1.00 0.92 C +ATOM 129 N LEU A 16 0.689 8.051 0.584 1.00 0.95 N +ATOM 130 CA LEU A 16 1.143 8.158 1.966 1.00 0.95 C +ATOM 131 C LEU A 16 1.813 9.505 2.215 1.00 0.95 C +ATOM 132 CB LEU A 16 2.113 7.022 2.301 1.00 0.95 C +ATOM 133 O LEU A 16 1.694 10.071 3.304 1.00 0.94 O +ATOM 134 CG LEU A 16 1.521 5.612 2.331 1.00 0.95 C +ATOM 135 CD1 LEU A 16 2.609 4.587 2.634 1.00 0.94 C +ATOM 136 CD2 LEU A 16 0.397 5.525 3.357 1.00 0.93 C +ATOM 137 N GLU A 17 2.509 10.095 1.227 1.00 0.94 N +ATOM 138 CA GLU A 17 3.177 11.387 1.356 1.00 0.94 C +ATOM 139 C GLU A 17 2.165 12.522 1.484 1.00 0.93 C +ATOM 140 CB GLU A 17 4.100 11.637 0.161 1.00 0.92 C +ATOM 141 O GLU A 17 2.413 13.505 2.184 1.00 0.92 O +ATOM 142 CG GLU A 17 5.412 10.868 0.225 1.00 0.86 C +ATOM 143 CD GLU A 17 6.272 11.044 -1.016 1.00 0.81 C +ATOM 144 OE1 GLU A 17 5.739 11.459 -2.070 1.00 0.78 O +ATOM 145 OE2 GLU A 17 7.489 10.764 -0.934 1.00 0.76 O +ATOM 146 N ARG A 18 1.030 12.289 0.890 1.00 0.93 N +ATOM 147 CA ARG A 18 0.060 13.378 0.835 1.00 0.93 C +ATOM 148 C ARG A 18 -0.916 13.301 2.003 1.00 0.92 C +ATOM 149 CB ARG A 18 -0.705 13.351 -0.490 1.00 0.91 C +ATOM 150 O ARG A 18 -1.588 14.284 2.323 1.00 0.91 O +ATOM 151 CG ARG A 18 0.139 13.731 -1.697 1.00 0.83 C +ATOM 152 CD ARG A 18 -0.656 13.640 -2.992 1.00 0.79 C +ATOM 153 NE ARG A 18 0.139 14.059 -4.143 1.00 0.73 N +ATOM 154 NH1 ARG A 18 -1.546 13.730 -5.688 1.00 0.56 N +ATOM 155 NH2 ARG A 18 0.507 14.490 -6.368 1.00 0.51 N +ATOM 156 CZ ARG A 18 -0.302 14.092 -5.397 1.00 0.71 C +ATOM 157 N SER A 19 -0.853 12.101 2.564 1.00 0.92 N +ATOM 158 CA SER A 19 -1.857 11.925 3.607 1.00 0.92 C +ATOM 159 C SER A 19 -1.372 12.481 4.942 1.00 0.91 C +ATOM 160 CB SER A 19 -2.215 10.446 3.762 1.00 0.91 C +ATOM 161 O SER A 19 -0.232 12.239 5.344 1.00 0.90 O +ATOM 162 OG SER A 19 -3.219 10.272 4.748 1.00 0.85 O +ATOM 163 N LYS A 20 -2.211 13.277 5.567 1.00 0.89 N +ATOM 164 CA LYS A 20 -1.915 13.785 6.903 1.00 0.89 C +ATOM 165 C LYS A 20 -2.272 12.759 7.974 1.00 0.89 C +ATOM 166 CB LYS A 20 -2.667 15.092 7.158 1.00 0.87 C +ATOM 167 O LYS A 20 -1.768 12.824 9.097 1.00 0.87 O +ATOM 168 CG LYS A 20 -2.206 16.252 6.287 1.00 0.79 C +ATOM 169 CD LYS A 20 -2.955 17.535 6.623 1.00 0.76 C +ATOM 170 CE LYS A 20 -2.516 18.689 5.732 1.00 0.68 C +ATOM 171 NZ LYS A 20 -3.289 19.935 6.018 1.00 0.61 N +ATOM 172 N GLU A 21 -3.098 11.887 7.683 1.00 0.92 N +ATOM 173 CA GLU A 21 -3.549 10.825 8.577 1.00 0.92 C +ATOM 174 C GLU A 21 -3.148 9.451 8.047 1.00 0.92 C +ATOM 175 CB GLU A 21 -5.066 10.892 8.770 1.00 0.90 C +ATOM 176 O GLU A 21 -2.881 9.294 6.854 1.00 0.92 O +ATOM 177 CG GLU A 21 -5.548 12.188 9.406 1.00 0.84 C +ATOM 178 CD GLU A 21 -7.025 12.165 9.769 1.00 0.80 C +ATOM 179 OE1 GLU A 21 -7.741 11.233 9.339 1.00 0.78 O +ATOM 180 OE2 GLU A 21 -7.468 13.088 10.489 1.00 0.74 O +ATOM 181 N PRO A 22 -3.069 8.392 8.977 1.00 0.94 N +ATOM 182 CA PRO A 22 -2.802 7.027 8.516 1.00 0.95 C +ATOM 183 C PRO A 22 -3.802 6.555 7.462 1.00 0.95 C +ATOM 184 CB PRO A 22 -2.921 6.193 9.794 1.00 0.94 C +ATOM 185 O PRO A 22 -4.990 6.878 7.544 1.00 0.94 O +ATOM 186 CG PRO A 22 -2.711 7.168 10.907 1.00 0.93 C +ATOM 187 CD PRO A 22 -3.262 8.500 10.485 1.00 0.91 C +ATOM 188 N VAL A 23 -3.318 5.865 6.476 1.00 0.95 N +ATOM 189 CA VAL A 23 -4.137 5.301 5.408 1.00 0.95 C +ATOM 190 C VAL A 23 -4.274 3.793 5.603 1.00 0.95 C +ATOM 191 CB VAL A 23 -3.543 5.607 4.015 1.00 0.95 C +ATOM 192 O VAL A 23 -3.273 3.074 5.652 1.00 0.95 O +ATOM 193 CG1 VAL A 23 -4.477 5.115 2.910 1.00 0.93 C +ATOM 194 CG2 VAL A 23 -3.276 7.103 3.866 1.00 0.93 C +ATOM 195 N SER A 24 -5.474 3.345 5.655 1.00 0.96 N +ATOM 196 CA SER A 24 -5.672 1.925 5.923 1.00 0.96 C +ATOM 197 C SER A 24 -5.316 1.077 4.706 1.00 0.96 C +ATOM 198 CB SER A 24 -7.119 1.653 6.338 1.00 0.95 C +ATOM 199 O SER A 24 -5.386 1.552 3.571 1.00 0.95 O +ATOM 200 OG SER A 24 -7.981 1.698 5.214 1.00 0.91 O +ATOM 201 N GLY A 25 -4.862 -0.173 5.000 1.00 0.95 N +ATOM 202 CA GLY A 25 -4.628 -1.110 3.914 1.00 0.95 C +ATOM 203 C GLY A 25 -5.840 -1.304 3.021 1.00 0.95 C +ATOM 204 O GLY A 25 -5.706 -1.426 1.802 1.00 0.95 O +ATOM 205 N ALA A 26 -7.029 -1.338 3.592 1.00 0.95 N +ATOM 206 CA ALA A 26 -8.269 -1.507 2.839 1.00 0.95 C +ATOM 207 C ALA A 26 -8.487 -0.346 1.873 1.00 0.95 C +ATOM 208 CB ALA A 26 -9.456 -1.633 3.790 1.00 0.94 C +ATOM 209 O ALA A 26 -8.901 -0.551 0.729 1.00 0.95 O +ATOM 210 N GLN A 27 -8.247 0.886 2.350 1.00 0.95 N +ATOM 211 CA GLN A 27 -8.373 2.066 1.501 1.00 0.95 C +ATOM 212 C GLN A 27 -7.389 2.013 0.335 1.00 0.95 C +ATOM 213 CB GLN A 27 -8.151 3.341 2.317 1.00 0.94 C +ATOM 214 O GLN A 27 -7.757 2.295 -0.807 1.00 0.95 O +ATOM 215 CG GLN A 27 -8.308 4.623 1.511 1.00 0.86 C +ATOM 216 CD GLN A 27 -8.034 5.870 2.330 1.00 0.81 C +ATOM 217 NE2 GLN A 27 -7.923 7.010 1.657 1.00 0.73 N +ATOM 218 OE1 GLN A 27 -7.923 5.809 3.559 1.00 0.78 O +ATOM 219 N LEU A 28 -6.152 1.593 0.619 1.00 0.96 N +ATOM 220 CA LEU A 28 -5.160 1.467 -0.444 1.00 0.96 C +ATOM 221 C LEU A 28 -5.574 0.395 -1.448 1.00 0.96 C +ATOM 222 CB LEU A 28 -3.787 1.131 0.142 1.00 0.95 C +ATOM 223 O LEU A 28 -5.474 0.602 -2.659 1.00 0.95 O +ATOM 224 CG LEU A 28 -3.083 2.253 0.906 1.00 0.95 C +ATOM 225 CD1 LEU A 28 -1.839 1.718 1.608 1.00 0.93 C +ATOM 226 CD2 LEU A 28 -2.721 3.397 -0.035 1.00 0.92 C +ATOM 227 N ALA A 29 -6.050 -0.750 -0.922 1.00 0.96 N +ATOM 228 CA ALA A 29 -6.463 -1.859 -1.778 1.00 0.96 C +ATOM 229 C ALA A 29 -7.599 -1.441 -2.708 1.00 0.96 C +ATOM 230 CB ALA A 29 -6.886 -3.056 -0.931 1.00 0.95 C +ATOM 231 O ALA A 29 -7.574 -1.741 -3.903 1.00 0.95 O +ATOM 232 N GLU A 30 -8.555 -0.688 -2.175 1.00 0.96 N +ATOM 233 CA GLU A 30 -9.687 -0.188 -2.949 1.00 0.95 C +ATOM 234 C GLU A 30 -9.235 0.828 -3.995 1.00 0.95 C +ATOM 235 CB GLU A 30 -10.735 0.440 -2.026 1.00 0.94 C +ATOM 236 O GLU A 30 -9.618 0.736 -5.163 1.00 0.94 O +ATOM 237 CG GLU A 30 -12.004 0.876 -2.744 1.00 0.85 C +ATOM 238 CD GLU A 30 -13.067 1.424 -1.804 1.00 0.79 C +ATOM 239 OE1 GLU A 30 -12.798 1.542 -0.587 1.00 0.77 O +ATOM 240 OE2 GLU A 30 -14.177 1.736 -2.288 1.00 0.74 O +ATOM 241 N GLU A 31 -8.407 1.749 -3.572 1.00 0.95 N +ATOM 242 CA GLU A 31 -7.963 2.822 -4.456 1.00 0.94 C +ATOM 243 C GLU A 31 -7.129 2.277 -5.612 1.00 0.94 C +ATOM 244 CB GLU A 31 -7.159 3.864 -3.674 1.00 0.92 C +ATOM 245 O GLU A 31 -7.197 2.791 -6.730 1.00 0.93 O +ATOM 246 CG GLU A 31 -6.777 5.089 -4.493 1.00 0.78 C +ATOM 247 CD GLU A 31 -6.323 6.263 -3.642 1.00 0.72 C +ATOM 248 OE1 GLU A 31 -6.684 6.319 -2.444 1.00 0.68 O +ATOM 249 OE2 GLU A 31 -5.603 7.135 -4.176 1.00 0.66 O +ATOM 250 N LEU A 32 -6.421 1.249 -5.368 1.00 0.94 N +ATOM 251 CA LEU A 32 -5.480 0.768 -6.373 1.00 0.94 C +ATOM 252 C LEU A 32 -6.005 -0.494 -7.050 1.00 0.94 C +ATOM 253 CB LEU A 32 -4.114 0.489 -5.738 1.00 0.94 C +ATOM 254 O LEU A 32 -5.323 -1.081 -7.893 1.00 0.92 O +ATOM 255 CG LEU A 32 -3.386 1.694 -5.140 1.00 0.92 C +ATOM 256 CD1 LEU A 32 -2.156 1.238 -4.363 1.00 0.89 C +ATOM 257 CD2 LEU A 32 -2.998 2.682 -6.234 1.00 0.89 C +ATOM 258 N SER A 33 -7.187 -0.923 -6.692 1.00 0.95 N +ATOM 259 CA SER A 33 -7.876 -2.070 -7.275 1.00 0.94 C +ATOM 260 C SER A 33 -7.028 -3.333 -7.174 1.00 0.94 C +ATOM 261 CB SER A 33 -8.228 -1.798 -8.738 1.00 0.93 C +ATOM 262 O SER A 33 -6.863 -4.057 -8.159 1.00 0.93 O +ATOM 263 OG SER A 33 -9.149 -0.726 -8.842 1.00 0.85 O +ATOM 264 N VAL A 34 -6.509 -3.606 -5.951 1.00 0.94 N +ATOM 265 CA VAL A 34 -5.794 -4.840 -5.646 1.00 0.94 C +ATOM 266 C VAL A 34 -6.250 -5.380 -4.292 1.00 0.94 C +ATOM 267 CB VAL A 34 -4.264 -4.625 -5.645 1.00 0.94 C +ATOM 268 O VAL A 34 -7.013 -4.724 -3.580 1.00 0.94 O +ATOM 269 CG1 VAL A 34 -3.771 -4.252 -7.042 1.00 0.91 C +ATOM 270 CG2 VAL A 34 -3.878 -3.547 -4.634 1.00 0.91 C +ATOM 271 N SER A 35 -5.841 -6.605 -4.013 1.00 0.95 N +ATOM 272 CA SER A 35 -6.185 -7.200 -2.725 1.00 0.95 C +ATOM 273 C SER A 35 -5.372 -6.579 -1.594 1.00 0.95 C +ATOM 274 CB SER A 35 -5.960 -8.712 -2.756 1.00 0.94 C +ATOM 275 O SER A 35 -4.314 -5.993 -1.833 1.00 0.95 O +ATOM 276 OG SER A 35 -4.575 -9.014 -2.769 1.00 0.87 O +ATOM 277 N ARG A 36 -5.839 -6.717 -0.444 1.00 0.96 N +ATOM 278 CA ARG A 36 -5.113 -6.257 0.736 1.00 0.96 C +ATOM 279 C ARG A 36 -3.765 -6.959 0.857 1.00 0.96 C +ATOM 280 CB ARG A 36 -5.941 -6.489 2.001 1.00 0.93 C +ATOM 281 O ARG A 36 -2.785 -6.360 1.306 1.00 0.95 O +ATOM 282 CG ARG A 36 -7.147 -5.571 2.126 1.00 0.76 C +ATOM 283 CD ARG A 36 -7.872 -5.769 3.449 1.00 0.72 C +ATOM 284 NE ARG A 36 -7.044 -5.369 4.583 1.00 0.69 N +ATOM 285 NH1 ARG A 36 -8.302 -6.492 6.163 1.00 0.58 N +ATOM 286 NH2 ARG A 36 -6.450 -5.302 6.800 1.00 0.52 N +ATOM 287 CZ ARG A 36 -7.267 -5.722 5.846 1.00 0.64 C +ATOM 288 N GLN A 37 -3.757 -8.247 0.479 1.00 0.96 N +ATOM 289 CA GLN A 37 -2.512 -9.005 0.531 1.00 0.96 C +ATOM 290 C GLN A 37 -1.446 -8.374 -0.361 1.00 0.96 C +ATOM 291 CB GLN A 37 -2.749 -10.458 0.117 1.00 0.94 C +ATOM 292 O GLN A 37 -0.273 -8.312 0.013 1.00 0.96 O +ATOM 293 CG GLN A 37 -1.503 -11.329 0.189 1.00 0.79 C +ATOM 294 CD GLN A 37 -1.003 -11.522 1.609 1.00 0.72 C +ATOM 295 NE2 GLN A 37 0.254 -11.931 1.744 1.00 0.59 N +ATOM 296 OE1 GLN A 37 -1.740 -11.305 2.576 1.00 0.68 O +ATOM 297 N VAL A 38 -1.860 -7.916 -1.492 1.00 0.96 N +ATOM 298 CA VAL A 38 -0.934 -7.261 -2.410 1.00 0.96 C +ATOM 299 C VAL A 38 -0.384 -5.989 -1.769 1.00 0.96 C +ATOM 300 CB VAL A 38 -1.612 -6.928 -3.758 1.00 0.95 C +ATOM 301 O VAL A 38 0.810 -5.699 -1.875 1.00 0.96 O +ATOM 302 CG1 VAL A 38 -0.732 -5.996 -4.589 1.00 0.93 C +ATOM 303 CG2 VAL A 38 -1.919 -8.209 -4.531 1.00 0.92 C +ATOM 304 N ILE A 39 -1.219 -5.306 -1.044 1.00 0.96 N +ATOM 305 CA ILE A 39 -0.801 -4.074 -0.385 1.00 0.96 C +ATOM 306 C ILE A 39 0.250 -4.387 0.677 1.00 0.96 C +ATOM 307 CB ILE A 39 -2.002 -3.337 0.250 1.00 0.96 C +ATOM 308 O ILE A 39 1.263 -3.692 0.781 1.00 0.96 O +ATOM 309 CG1 ILE A 39 -2.970 -2.857 -0.838 1.00 0.94 C +ATOM 310 CG2 ILE A 39 -1.522 -2.166 1.112 1.00 0.94 C +ATOM 311 CD1 ILE A 39 -2.336 -1.930 -1.865 1.00 0.91 C +ATOM 312 N VAL A 40 0.033 -5.399 1.497 1.00 0.96 N +ATOM 313 CA VAL A 40 0.963 -5.793 2.550 1.00 0.96 C +ATOM 314 C VAL A 40 2.317 -6.146 1.940 1.00 0.97 C +ATOM 315 CB VAL A 40 0.420 -6.987 3.368 1.00 0.96 C +ATOM 316 O VAL A 40 3.362 -5.740 2.454 1.00 0.96 O +ATOM 317 CG1 VAL A 40 1.503 -7.549 4.287 1.00 0.89 C +ATOM 318 CG2 VAL A 40 -0.806 -6.565 4.177 1.00 0.89 C +ATOM 319 N GLN A 41 2.280 -6.826 0.823 1.00 0.96 N +ATOM 320 CA GLN A 41 3.510 -7.216 0.142 1.00 0.96 C +ATOM 321 C GLN A 41 4.236 -5.998 -0.424 1.00 0.96 C +ATOM 322 CB GLN A 41 3.211 -8.215 -0.977 1.00 0.95 C +ATOM 323 O GLN A 41 5.463 -5.909 -0.348 1.00 0.95 O +ATOM 324 CG GLN A 41 2.779 -9.586 -0.477 1.00 0.86 C +ATOM 325 CD GLN A 41 2.333 -10.506 -1.598 1.00 0.79 C +ATOM 326 NE2 GLN A 41 2.103 -11.773 -1.270 1.00 0.69 N +ATOM 327 OE1 GLN A 41 2.196 -10.082 -2.750 1.00 0.77 O +ATOM 328 N ASP A 42 3.536 -5.124 -0.987 1.00 0.96 N +ATOM 329 CA ASP A 42 4.119 -3.918 -1.568 1.00 0.96 C +ATOM 330 C ASP A 42 4.728 -3.027 -0.487 1.00 0.96 C +ATOM 331 CB ASP A 42 3.066 -3.140 -2.359 1.00 0.95 C +ATOM 332 O ASP A 42 5.806 -2.461 -0.677 1.00 0.95 O +ATOM 333 CG ASP A 42 2.757 -3.764 -3.709 1.00 0.94 C +ATOM 334 OD1 ASP A 42 3.553 -4.599 -4.191 1.00 0.91 O +ATOM 335 OD2 ASP A 42 1.711 -3.416 -4.297 1.00 0.92 O +ATOM 336 N ILE A 43 4.006 -2.921 0.639 1.00 0.96 N +ATOM 337 CA ILE A 43 4.512 -2.107 1.738 1.00 0.96 C +ATOM 338 C ILE A 43 5.806 -2.713 2.276 1.00 0.96 C +ATOM 339 CB ILE A 43 3.470 -1.976 2.871 1.00 0.96 C +ATOM 340 O ILE A 43 6.770 -1.994 2.548 1.00 0.96 O +ATOM 341 CG1 ILE A 43 2.293 -1.106 2.416 1.00 0.94 C +ATOM 342 CG2 ILE A 43 4.117 -1.404 4.136 1.00 0.93 C +ATOM 343 CD1 ILE A 43 2.657 0.352 2.174 1.00 0.91 C +ATOM 344 N ALA A 44 5.851 -4.052 2.411 1.00 0.96 N +ATOM 345 CA ALA A 44 7.075 -4.731 2.830 1.00 0.96 C +ATOM 346 C ALA A 44 8.218 -4.451 1.859 1.00 0.96 C +ATOM 347 CB ALA A 44 6.837 -6.234 2.947 1.00 0.96 C +ATOM 348 O ALA A 44 9.353 -4.213 2.278 1.00 0.96 O +ATOM 349 N TYR A 45 7.872 -4.425 0.639 1.00 0.95 N +ATOM 350 CA TYR A 45 8.877 -4.165 -0.387 1.00 0.95 C +ATOM 351 C TYR A 45 9.363 -2.723 -0.320 1.00 0.95 C +ATOM 352 CB TYR A 45 8.312 -4.461 -1.780 1.00 0.95 C +ATOM 353 O TYR A 45 10.568 -2.464 -0.380 1.00 0.95 O +ATOM 354 CG TYR A 45 9.316 -4.279 -2.893 1.00 0.93 C +ATOM 355 CD1 TYR A 45 10.439 -5.098 -2.985 1.00 0.89 C +ATOM 356 CD2 TYR A 45 9.143 -3.288 -3.853 1.00 0.88 C +ATOM 357 CE1 TYR A 45 11.367 -4.933 -4.008 1.00 0.88 C +ATOM 358 CE2 TYR A 45 10.065 -3.113 -4.880 1.00 0.88 C +ATOM 359 OH TYR A 45 12.088 -3.771 -5.963 1.00 0.79 O +ATOM 360 CZ TYR A 45 11.172 -3.940 -4.949 1.00 0.86 C +ATOM 361 N LEU A 46 8.521 -1.815 -0.237 1.00 0.95 N +ATOM 362 CA LEU A 46 8.894 -0.409 -0.123 1.00 0.95 C +ATOM 363 C LEU A 46 9.792 -0.181 1.088 1.00 0.95 C +ATOM 364 CB LEU A 46 7.645 0.470 -0.019 1.00 0.95 C +ATOM 365 O LEU A 46 10.747 0.595 1.021 1.00 0.95 O +ATOM 366 CG LEU A 46 6.847 0.669 -1.309 1.00 0.95 C +ATOM 367 CD1 LEU A 46 5.518 1.356 -1.010 1.00 0.93 C +ATOM 368 CD2 LEU A 46 7.656 1.476 -2.319 1.00 0.93 C +ATOM 369 N ARG A 47 9.531 -0.912 2.192 1.00 0.96 N +ATOM 370 CA ARG A 47 10.387 -0.815 3.370 1.00 0.96 C +ATOM 371 C ARG A 47 11.791 -1.332 3.072 1.00 0.96 C +ATOM 372 CB ARG A 47 9.781 -1.591 4.541 1.00 0.95 C +ATOM 373 O ARG A 47 12.781 -0.740 3.506 1.00 0.95 O +ATOM 374 CG ARG A 47 8.562 -0.923 5.158 1.00 0.93 C +ATOM 375 CD ARG A 47 8.006 -1.730 6.323 1.00 0.91 C +ATOM 376 NE ARG A 47 6.966 -0.996 7.039 1.00 0.90 N +ATOM 377 NH1 ARG A 47 5.819 -2.880 7.724 1.00 0.83 N +ATOM 378 NH2 ARG A 47 5.061 -0.797 8.306 1.00 0.81 N +ATOM 379 CZ ARG A 47 5.951 -1.559 7.688 1.00 0.87 C +ATOM 380 N SER A 48 11.822 -2.364 2.346 1.00 0.96 N +ATOM 381 CA SER A 48 13.124 -2.927 2.003 1.00 0.96 C +ATOM 382 C SER A 48 13.929 -1.969 1.131 1.00 0.95 C +ATOM 383 CB SER A 48 12.957 -4.266 1.283 1.00 0.95 C +ATOM 384 O SER A 48 15.159 -2.041 1.091 1.00 0.94 O +ATOM 385 OG SER A 48 12.598 -4.066 -0.073 1.00 0.90 O +ATOM 386 N LEU A 49 13.228 -1.054 0.452 1.00 0.95 N +ATOM 387 CA LEU A 49 13.904 -0.075 -0.393 1.00 0.94 C +ATOM 388 C LEU A 49 14.342 1.137 0.423 1.00 0.94 C +ATOM 389 CB LEU A 49 12.989 0.368 -1.537 1.00 0.94 C +ATOM 390 O LEU A 49 14.979 2.049 -0.107 1.00 0.92 O +ATOM 391 CG LEU A 49 12.691 -0.678 -2.612 1.00 0.89 C +ATOM 392 CD1 LEU A 49 11.737 -0.109 -3.656 1.00 0.83 C +ATOM 393 CD2 LEU A 49 13.984 -1.156 -3.265 1.00 0.83 C +ATOM 394 N GLY A 50 13.868 1.196 1.683 1.00 0.94 N +ATOM 395 CA GLY A 50 14.344 2.263 2.549 1.00 0.94 C +ATOM 396 C GLY A 50 13.258 3.253 2.927 1.00 0.94 C +ATOM 397 O GLY A 50 13.514 4.216 3.652 1.00 0.93 O +ATOM 398 N TYR A 51 12.070 3.128 2.433 1.00 0.94 N +ATOM 399 CA TYR A 51 10.982 4.007 2.846 1.00 0.94 C +ATOM 400 C TYR A 51 10.598 3.753 4.299 1.00 0.94 C +ATOM 401 CB TYR A 51 9.760 3.812 1.942 1.00 0.94 C +ATOM 402 O TYR A 51 10.466 2.601 4.721 1.00 0.93 O +ATOM 403 CG TYR A 51 9.971 4.290 0.526 1.00 0.93 C +ATOM 404 CD1 TYR A 51 9.767 5.625 0.183 1.00 0.92 C +ATOM 405 CD2 TYR A 51 10.373 3.408 -0.472 1.00 0.91 C +ATOM 406 CE1 TYR A 51 9.958 6.069 -1.121 1.00 0.91 C +ATOM 407 CE2 TYR A 51 10.567 3.842 -1.779 1.00 0.91 C +ATOM 408 OH TYR A 51 10.548 5.607 -3.386 1.00 0.87 O +ATOM 409 CZ TYR A 51 10.358 5.172 -2.093 1.00 0.91 C +ATOM 410 N ASN A 52 10.429 4.810 5.078 1.00 0.95 N +ATOM 411 CA ASN A 52 10.061 4.716 6.487 1.00 0.95 C +ATOM 412 C ASN A 52 8.547 4.669 6.670 1.00 0.95 C +ATOM 413 CB ASN A 52 10.656 5.885 7.276 1.00 0.94 C +ATOM 414 O ASN A 52 7.960 5.581 7.255 1.00 0.94 O +ATOM 415 CG ASN A 52 10.661 5.638 8.772 1.00 0.86 C +ATOM 416 ND2 ASN A 52 10.958 6.677 9.543 1.00 0.77 N +ATOM 417 OD1 ASN A 52 10.401 4.522 9.230 1.00 0.75 O +ATOM 418 N ILE A 53 7.934 3.537 6.187 1.00 0.95 N +ATOM 419 CA ILE A 53 6.498 3.323 6.325 1.00 0.96 C +ATOM 420 C ILE A 53 6.209 2.590 7.633 1.00 0.95 C +ATOM 421 CB ILE A 53 5.927 2.530 5.128 1.00 0.95 C +ATOM 422 O ILE A 53 6.695 1.477 7.849 1.00 0.94 O +ATOM 423 CG1 ILE A 53 6.259 3.239 3.810 1.00 0.94 C +ATOM 424 CG2 ILE A 53 4.416 2.335 5.281 1.00 0.94 C +ATOM 425 CD1 ILE A 53 5.911 2.431 2.568 1.00 0.93 C +ATOM 426 N VAL A 54 5.441 3.118 8.475 1.00 0.95 N +ATOM 427 CA VAL A 54 5.115 2.530 9.770 1.00 0.95 C +ATOM 428 C VAL A 54 3.650 2.103 9.791 1.00 0.95 C +ATOM 429 CB VAL A 54 5.400 3.514 10.927 1.00 0.94 C +ATOM 430 O VAL A 54 2.779 2.826 9.299 1.00 0.95 O +ATOM 431 CG1 VAL A 54 4.993 2.903 12.267 1.00 0.78 C +ATOM 432 CG2 VAL A 54 6.876 3.906 10.942 1.00 0.78 C +ATOM 433 N ALA A 55 3.436 0.986 10.239 1.00 0.95 N +ATOM 434 CA ALA A 55 2.086 0.462 10.428 1.00 0.95 C +ATOM 435 C ALA A 55 1.527 0.864 11.790 1.00 0.94 C +ATOM 436 CB ALA A 55 2.080 -1.057 10.281 1.00 0.94 C +ATOM 437 O ALA A 55 2.203 0.723 12.811 1.00 0.93 O +ATOM 438 N THR A 56 0.347 1.432 11.827 1.00 0.93 N +ATOM 439 CA THR A 56 -0.403 1.797 13.024 1.00 0.93 C +ATOM 440 C THR A 56 -1.730 1.046 13.080 1.00 0.93 C +ATOM 441 CB THR A 56 -0.665 3.314 13.077 1.00 0.92 C +ATOM 442 O THR A 56 -2.129 0.405 12.106 1.00 0.92 O +ATOM 443 CG2 THR A 56 0.585 4.102 12.702 1.00 0.87 C +ATOM 444 OG1 THR A 56 -1.717 3.643 12.161 1.00 0.88 O +ATOM 445 N PRO A 57 -2.436 0.978 14.221 1.00 0.92 N +ATOM 446 CA PRO A 57 -3.759 0.351 14.257 1.00 0.92 C +ATOM 447 C PRO A 57 -4.713 0.927 13.214 1.00 0.91 C +ATOM 448 CB PRO A 57 -4.253 0.651 15.675 1.00 0.91 C +ATOM 449 O PRO A 57 -5.663 0.255 12.803 1.00 0.89 O +ATOM 450 CG PRO A 57 -3.010 0.760 16.497 1.00 0.89 C +ATOM 451 CD PRO A 57 -1.939 1.398 15.660 1.00 0.88 C +ATOM 452 N ARG A 58 -4.402 2.198 12.767 1.00 0.94 N +ATOM 453 CA ARG A 58 -5.325 2.830 11.831 1.00 0.94 C +ATOM 454 C ARG A 58 -4.823 2.702 10.396 1.00 0.93 C +ATOM 455 CB ARG A 58 -5.525 4.305 12.186 1.00 0.92 C +ATOM 456 O ARG A 58 -5.517 3.089 9.454 1.00 0.92 O +ATOM 457 CG ARG A 58 -6.256 4.529 13.500 1.00 0.86 C +ATOM 458 CD ARG A 58 -6.551 6.003 13.738 1.00 0.82 C +ATOM 459 NE ARG A 58 -5.333 6.759 14.014 1.00 0.77 N +ATOM 460 NH1 ARG A 58 -6.405 8.786 14.289 1.00 0.64 N +ATOM 461 NH2 ARG A 58 -4.128 8.650 14.509 1.00 0.59 N +ATOM 462 CZ ARG A 58 -5.291 8.063 14.270 1.00 0.75 C +ATOM 463 N GLY A 59 -3.702 2.248 10.206 1.00 0.95 N +ATOM 464 CA GLY A 59 -3.182 2.097 8.857 1.00 0.95 C +ATOM 465 C GLY A 59 -1.700 2.406 8.749 1.00 0.95 C +ATOM 466 O GLY A 59 -0.945 2.190 9.699 1.00 0.95 O +ATOM 467 N TYR A 60 -1.248 2.930 7.637 1.00 0.96 N +ATOM 468 CA TYR A 60 0.157 3.167 7.325 1.00 0.96 C +ATOM 469 C TYR A 60 0.457 4.660 7.265 1.00 0.96 C +ATOM 470 CB TYR A 60 0.531 2.505 5.996 1.00 0.96 C +ATOM 471 O TYR A 60 -0.380 5.451 6.824 1.00 0.95 O +ATOM 472 CG TYR A 60 0.342 1.008 5.988 1.00 0.95 C +ATOM 473 CD1 TYR A 60 1.278 0.165 6.583 1.00 0.94 C +ATOM 474 CD2 TYR A 60 -0.772 0.433 5.386 1.00 0.94 C +ATOM 475 CE1 TYR A 60 1.109 -1.216 6.577 1.00 0.94 C +ATOM 476 CE2 TYR A 60 -0.952 -0.946 5.374 1.00 0.94 C +ATOM 477 OH TYR A 60 -0.180 -3.127 5.962 1.00 0.90 O +ATOM 478 CZ TYR A 60 -0.008 -1.761 5.971 1.00 0.93 C +ATOM 479 N VAL A 61 1.559 5.020 7.726 1.00 0.95 N +ATOM 480 CA VAL A 61 2.043 6.393 7.628 1.00 0.95 C +ATOM 481 C VAL A 61 3.484 6.399 7.124 1.00 0.95 C +ATOM 482 CB VAL A 61 1.950 7.126 8.985 1.00 0.93 C +ATOM 483 O VAL A 61 4.263 5.496 7.439 1.00 0.94 O +ATOM 484 CG1 VAL A 61 0.504 7.172 9.476 1.00 0.75 C +ATOM 485 CG2 VAL A 61 2.847 6.448 10.019 1.00 0.76 C +ATOM 486 N LEU A 62 3.751 7.326 6.213 1.00 0.95 N +ATOM 487 CA LEU A 62 5.136 7.577 5.829 1.00 0.95 C +ATOM 488 C LEU A 62 5.806 8.537 6.807 1.00 0.94 C +ATOM 489 CB LEU A 62 5.205 8.146 4.410 1.00 0.94 C +ATOM 490 O LEU A 62 5.536 9.740 6.785 1.00 0.92 O +ATOM 491 CG LEU A 62 6.604 8.327 3.819 1.00 0.89 C +ATOM 492 CD1 LEU A 62 7.315 6.982 3.717 1.00 0.83 C +ATOM 493 CD2 LEU A 62 6.525 9.001 2.453 1.00 0.82 C +ATOM 494 N ALA A 63 6.595 7.972 7.715 1.00 0.91 N +ATOM 495 CA ALA A 63 7.245 8.760 8.759 1.00 0.91 C +ATOM 496 C ALA A 63 8.462 9.500 8.211 1.00 0.88 C +ATOM 497 CB ALA A 63 7.653 7.864 9.926 1.00 0.87 C +ATOM 498 O ALA A 63 9.150 9.000 7.317 1.00 0.84 O +ATOM 499 N GLY A 64 8.844 10.801 8.768 1.00 0.79 N +ATOM 500 CA GLY A 64 10.029 11.551 8.385 1.00 0.77 C +ATOM 501 C GLY A 64 9.839 12.359 7.115 1.00 0.76 C +ATOM 502 O GLY A 64 10.811 12.831 6.522 1.00 0.70 O +ATOM 503 N GLY A 65 8.383 12.399 6.587 1.00 0.54 N +ATOM 504 CA GLY A 65 8.133 13.333 5.501 1.00 0.54 C +ATOM 505 C GLY A 65 7.712 14.709 5.983 1.00 0.53 C +ATOM 506 O GLY A 65 7.142 14.845 7.067 1.00 0.51 O \ No newline at end of file diff --git a/esm/mcp_output/predictions/prediction_20250830_220641.pdb b/esm/mcp_output/predictions/prediction_20250830_220641.pdb new file mode 100644 index 0000000000000000000000000000000000000000..3f6b007cb3a53c9a68a685ba3294a055c168a3ad --- /dev/null +++ b/esm/mcp_output/predictions/prediction_20250830_220641.pdb @@ -0,0 +1,489 @@ +HEADER 18-OCT-22 +TITLE ESMFOLD V1 PREDICTION FOR INPUT +REMARK 1 +REMARK 1 REFERENCE 1 +REMARK 1 AUTH ZEMING LIN, HALIL AKIN, ROSHAN RAO, BRIAN HIE, ZHONGKAI ZHU, +REMARK 1 AUTH 2 WENTING LU, NIKITA SMETANIN, ROBERT VERKUIL, ORI KABELI, +REMARK 1 AUTH 3 YANIV SHMUELI, ALLAN DOS SANTOS COSTA, +REMARK 1 AUTH 4 MARYAM FAZEL-ZARANDI, TOM SERCU, SALVATORE CANDIDO, +REMARK 1 AUTH 5 ALEXANDER RIVES +REMARK 1 TITL EVOLUTIONARY-SCALE PREDICTION OF ATOMIC LEVEL PROTEIN +REMARK 1 TITL 2 STRUCTURE WITH A LANGUAGE MODEL +REMARK 1 REF +REMARK 1 REFN +REMARK 1 PMID +REMARK 1 DOI 10.1101/2022.07.20.500902 +REMARK 1 +REMARK 1 LICENSE AND DISCLAIMERS +REMARK 1 ESM METAGENOMIC ATLAS DATA IS AVAILABLE UNDER +REMARK 1 A CC-BY-4.0 LICENSE FOR ACADEMIC AND COMMERCIAL USE. +REMARK 1 COPYRIGHT (C) META PLATFORMS, INC. ALL RIGHTS RESERVED. +REMARK 1 USE OF THE ESM METAGENOMIC ATLAS DATA IS SUBJECT +REMARK 1 TO THE META OPEN SOURCE TERMS OF USE AND PRIVACY POLICY. +ATOM 1 N MET A 1 12.955 22.762 2.808 1.00 0.40 N +ATOM 2 CA MET A 1 13.442 21.402 3.023 1.00 0.43 C +ATOM 3 C MET A 1 12.281 20.416 3.108 1.00 0.41 C +ATOM 4 CB MET A 1 14.285 21.328 4.297 1.00 0.37 C +ATOM 5 O MET A 1 11.322 20.643 3.847 1.00 0.40 O +ATOM 6 CG MET A 1 15.524 20.457 4.162 1.00 0.36 C +ATOM 7 SD MET A 1 16.674 20.646 5.579 1.00 0.46 S +ATOM 8 CE MET A 1 16.455 19.037 6.387 1.00 0.35 C +ATOM 9 N LYS A 2 11.743 19.862 2.050 1.00 0.44 N +ATOM 10 CA LYS A 2 10.680 18.862 2.091 1.00 0.48 C +ATOM 11 C LYS A 2 10.854 17.924 3.282 1.00 0.45 C +ATOM 12 CB LYS A 2 10.648 18.058 0.791 1.00 0.41 C +ATOM 13 O LYS A 2 11.967 17.481 3.573 1.00 0.44 O +ATOM 14 CG LYS A 2 9.807 18.691 -0.308 1.00 0.40 C +ATOM 15 CD LYS A 2 9.743 17.804 -1.544 1.00 0.44 C +ATOM 16 CE LYS A 2 8.931 18.452 -2.657 1.00 0.42 C +ATOM 17 NZ LYS A 2 8.883 17.595 -3.880 1.00 0.37 N +ATOM 18 N THR A 3 10.260 18.153 4.498 1.00 0.59 N +ATOM 19 CA THR A 3 10.394 17.359 5.714 1.00 0.62 C +ATOM 20 C THR A 3 10.444 15.870 5.386 1.00 0.57 C +ATOM 21 CB THR A 3 9.235 17.633 6.691 1.00 0.52 C +ATOM 22 O THR A 3 10.034 15.454 4.300 1.00 0.52 O +ATOM 23 CG2 THR A 3 9.446 18.945 7.440 1.00 0.42 C +ATOM 24 OG1 THR A 3 8.007 17.707 5.957 1.00 0.44 O +ATOM 25 N VAL A 4 11.392 14.978 5.807 1.00 0.55 N +ATOM 26 CA VAL A 4 11.478 13.527 5.688 1.00 0.55 C +ATOM 27 C VAL A 4 10.083 12.942 5.476 1.00 0.55 C +ATOM 28 CB VAL A 4 12.139 12.893 6.932 1.00 0.50 C +ATOM 29 O VAL A 4 9.905 12.019 4.678 1.00 0.54 O +ATOM 30 CG1 VAL A 4 12.097 11.368 6.849 1.00 0.40 C +ATOM 31 CG2 VAL A 4 13.578 13.384 7.080 1.00 0.41 C +ATOM 32 N ARG A 5 9.045 13.367 6.280 1.00 0.59 N +ATOM 33 CA ARG A 5 7.679 12.859 6.208 1.00 0.59 C +ATOM 34 C ARG A 5 7.124 12.979 4.793 1.00 0.58 C +ATOM 35 CB ARG A 5 6.775 13.607 7.191 1.00 0.55 C +ATOM 36 O ARG A 5 6.507 12.043 4.280 1.00 0.57 O +ATOM 37 CG ARG A 5 5.520 12.841 7.578 1.00 0.51 C +ATOM 38 CD ARG A 5 4.719 13.573 8.645 1.00 0.53 C +ATOM 39 NE ARG A 5 3.461 12.892 8.938 1.00 0.46 N +ATOM 40 NH1 ARG A 5 2.718 14.472 10.450 1.00 0.36 N +ATOM 41 NH2 ARG A 5 1.430 12.635 9.979 1.00 0.32 N +ATOM 42 CZ ARG A 5 2.539 13.335 9.788 1.00 0.47 C +ATOM 43 N GLN A 6 7.225 14.159 4.296 1.00 0.54 N +ATOM 44 CA GLN A 6 6.739 14.443 2.950 1.00 0.53 C +ATOM 45 C GLN A 6 7.437 13.564 1.916 1.00 0.54 C +ATOM 46 CB GLN A 6 6.942 15.920 2.607 1.00 0.49 C +ATOM 47 O GLN A 6 6.804 13.084 0.974 1.00 0.53 O +ATOM 48 CG GLN A 6 5.903 16.844 3.227 1.00 0.46 C +ATOM 49 CD GLN A 6 6.171 18.309 2.935 1.00 0.48 C +ATOM 50 NE2 GLN A 6 5.132 19.132 3.031 1.00 0.42 N +ATOM 51 OE1 GLN A 6 7.302 18.697 2.626 1.00 0.54 O +ATOM 52 N GLU A 7 8.751 13.356 2.208 1.00 0.53 N +ATOM 53 CA GLU A 7 9.522 12.566 1.253 1.00 0.51 C +ATOM 54 C GLU A 7 9.048 11.115 1.229 1.00 0.52 C +ATOM 55 CB GLU A 7 11.015 12.627 1.585 1.00 0.49 C +ATOM 56 O GLU A 7 8.959 10.504 0.162 1.00 0.52 O +ATOM 57 CG GLU A 7 11.700 13.898 1.106 1.00 0.45 C +ATOM 58 CD GLU A 7 13.193 13.920 1.394 1.00 0.47 C +ATOM 59 OE1 GLU A 7 13.697 12.984 2.054 1.00 0.53 O +ATOM 60 OE2 GLU A 7 13.863 14.882 0.956 1.00 0.48 O +ATOM 61 N ARG A 8 8.906 10.459 2.342 1.00 0.54 N +ATOM 62 CA ARG A 8 8.501 9.057 2.381 1.00 0.53 C +ATOM 63 C ARG A 8 7.127 8.866 1.748 1.00 0.54 C +ATOM 64 CB ARG A 8 8.491 8.540 3.821 1.00 0.52 C +ATOM 65 O ARG A 8 6.894 7.883 1.042 1.00 0.53 O +ATOM 66 CG ARG A 8 9.859 8.124 4.336 1.00 0.50 C +ATOM 67 CD ARG A 8 9.777 7.520 5.731 1.00 0.51 C +ATOM 68 NE ARG A 8 11.087 7.083 6.207 1.00 0.45 N +ATOM 69 NH1 ARG A 8 10.307 6.243 8.213 1.00 0.37 N +ATOM 70 NH2 ARG A 8 12.540 6.130 7.708 1.00 0.33 N +ATOM 71 CZ ARG A 8 11.308 6.486 7.375 1.00 0.48 C +ATOM 72 N LEU A 9 6.231 9.830 2.211 1.00 0.55 N +ATOM 73 CA LEU A 9 4.899 9.731 1.624 1.00 0.54 C +ATOM 74 C LEU A 9 4.969 9.810 0.103 1.00 0.55 C +ATOM 75 CB LEU A 9 3.992 10.840 2.163 1.00 0.52 C +ATOM 76 O LEU A 9 4.234 9.107 -0.594 1.00 0.55 O +ATOM 77 CG LEU A 9 3.348 10.585 3.527 1.00 0.50 C +ATOM 78 CD1 LEU A 9 2.845 11.893 4.128 1.00 0.45 C +ATOM 79 CD2 LEU A 9 2.211 9.577 3.402 1.00 0.47 C +ATOM 80 N LEU A 10 5.770 10.725 -0.331 1.00 0.49 N +ATOM 81 CA LEU A 10 5.935 10.895 -1.770 1.00 0.48 C +ATOM 82 C LEU A 10 6.431 9.605 -2.417 1.00 0.49 C +ATOM 83 CB LEU A 10 6.911 12.036 -2.067 1.00 0.46 C +ATOM 84 O LEU A 10 5.980 9.237 -3.503 1.00 0.49 O +ATOM 85 CG LEU A 10 6.296 13.336 -2.587 1.00 0.43 C +ATOM 86 CD1 LEU A 10 6.864 14.532 -1.829 1.00 0.38 C +ATOM 87 CD2 LEU A 10 6.540 13.481 -4.085 1.00 0.41 C +ATOM 88 N LYS A 11 7.442 8.965 -1.722 1.00 0.51 N +ATOM 89 CA LYS A 11 8.010 7.762 -2.324 1.00 0.50 C +ATOM 90 C LYS A 11 6.960 6.663 -2.454 1.00 0.51 C +ATOM 91 CB LYS A 11 9.197 7.258 -1.501 1.00 0.48 C +ATOM 92 O LYS A 11 6.940 5.930 -3.445 1.00 0.51 O +ATOM 93 CG LYS A 11 10.514 7.947 -1.828 1.00 0.46 C +ATOM 94 CD LYS A 11 11.665 7.365 -1.017 1.00 0.49 C +ATOM 95 CE LYS A 11 12.973 8.092 -1.300 1.00 0.43 C +ATOM 96 NZ LYS A 11 14.104 7.528 -0.504 1.00 0.40 N +ATOM 97 N ILE A 12 6.178 6.565 -1.403 1.00 0.53 N +ATOM 98 CA ILE A 12 5.147 5.534 -1.450 1.00 0.52 C +ATOM 99 C ILE A 12 4.183 5.820 -2.599 1.00 0.53 C +ATOM 100 CB ILE A 12 4.377 5.443 -0.114 1.00 0.51 C +ATOM 101 O ILE A 12 3.739 4.899 -3.289 1.00 0.54 O +ATOM 102 CG1 ILE A 12 5.283 4.883 0.988 1.00 0.45 C +ATOM 103 CG2 ILE A 12 3.117 4.587 -0.274 1.00 0.46 C +ATOM 104 CD1 ILE A 12 4.733 5.067 2.396 1.00 0.45 C +ATOM 105 N SER A 13 3.703 7.056 -2.575 1.00 0.53 N +ATOM 106 CA SER A 13 2.823 7.481 -3.659 1.00 0.52 C +ATOM 107 C SER A 13 3.421 7.144 -5.020 1.00 0.53 C +ATOM 108 CB SER A 13 2.549 8.982 -3.570 1.00 0.50 C +ATOM 109 O SER A 13 2.699 6.764 -5.945 1.00 0.53 O +ATOM 110 OG SER A 13 1.700 9.275 -2.474 1.00 0.49 O +ATOM 111 N LEU A 14 4.831 7.388 -5.129 1.00 0.48 N +ATOM 112 CA LEU A 14 5.477 7.149 -6.415 1.00 0.47 C +ATOM 113 C LEU A 14 5.426 5.669 -6.781 1.00 0.48 C +ATOM 114 CB LEU A 14 6.930 7.629 -6.382 1.00 0.44 C +ATOM 115 O LEU A 14 5.233 5.321 -7.948 1.00 0.47 O +ATOM 116 CG LEU A 14 7.205 9.002 -6.998 1.00 0.42 C +ATOM 117 CD1 LEU A 14 8.185 9.785 -6.130 1.00 0.36 C +ATOM 118 CD2 LEU A 14 7.740 8.854 -8.418 1.00 0.40 C +ATOM 119 N VAL A 15 5.762 4.833 -5.746 1.00 0.52 N +ATOM 120 CA VAL A 15 5.724 3.409 -6.064 1.00 0.51 C +ATOM 121 C VAL A 15 4.335 3.031 -6.573 1.00 0.52 C +ATOM 122 CB VAL A 15 6.097 2.543 -4.840 1.00 0.49 C +ATOM 123 O VAL A 15 4.204 2.238 -7.509 1.00 0.51 O +ATOM 124 CG1 VAL A 15 5.908 1.060 -5.150 1.00 0.44 C +ATOM 125 CG2 VAL A 15 7.536 2.823 -4.408 1.00 0.46 C +ATOM 126 N LEU A 16 3.392 3.725 -5.916 1.00 0.55 N +ATOM 127 CA LEU A 16 2.029 3.405 -6.323 1.00 0.54 C +ATOM 128 C LEU A 16 1.741 3.935 -7.724 1.00 0.55 C +ATOM 129 CB LEU A 16 1.021 3.986 -5.328 1.00 0.52 C +ATOM 130 O LEU A 16 0.957 3.342 -8.468 1.00 0.55 O +ATOM 131 CG LEU A 16 0.971 3.325 -3.950 1.00 0.50 C +ATOM 132 CD1 LEU A 16 0.096 4.140 -3.003 1.00 0.46 C +ATOM 133 CD2 LEU A 16 0.458 1.893 -4.061 1.00 0.47 C +ATOM 134 N SER A 17 2.343 5.204 -7.894 1.00 0.49 N +ATOM 135 CA SER A 17 2.073 5.808 -9.195 1.00 0.48 C +ATOM 136 C SER A 17 2.809 5.072 -10.309 1.00 0.49 C +ATOM 137 CB SER A 17 2.475 7.284 -9.195 1.00 0.45 C +ATOM 138 O SER A 17 2.409 5.139 -11.474 1.00 0.48 O +ATOM 139 OG SER A 17 3.880 7.422 -9.077 1.00 0.43 O +ATOM 140 N GLU A 18 4.061 4.645 -9.888 1.00 0.51 N +ATOM 141 CA GLU A 18 4.832 3.986 -10.938 1.00 0.50 C +ATOM 142 C GLU A 18 4.292 2.588 -11.224 1.00 0.51 C +ATOM 143 CB GLU A 18 6.311 3.910 -10.552 1.00 0.47 C +ATOM 144 O GLU A 18 4.769 1.907 -12.134 1.00 0.50 O +ATOM 145 CG GLU A 18 6.999 5.266 -10.482 1.00 0.45 C +ATOM 146 CD GLU A 18 8.505 5.185 -10.674 1.00 0.47 C +ATOM 147 OE1 GLU A 18 9.058 4.062 -10.671 1.00 0.48 O +ATOM 148 OE2 GLU A 18 9.138 6.254 -10.827 1.00 0.42 O +ATOM 149 N LEU A 19 3.449 2.137 -10.297 1.00 0.52 N +ATOM 150 CA LEU A 19 2.839 0.883 -10.722 1.00 0.52 C +ATOM 151 C LEU A 19 2.051 1.073 -12.014 1.00 0.52 C +ATOM 152 CB LEU A 19 1.921 0.334 -9.627 1.00 0.50 C +ATOM 153 O LEU A 19 1.400 2.103 -12.204 1.00 0.52 O +ATOM 154 CG LEU A 19 2.610 -0.333 -8.436 1.00 0.49 C +ATOM 155 CD1 LEU A 19 1.682 -0.348 -7.226 1.00 0.47 C +ATOM 156 CD2 LEU A 19 3.050 -1.748 -8.796 1.00 0.48 C +ATOM 157 N PRO A 20 2.509 0.425 -12.947 1.00 0.52 N +ATOM 158 CA PRO A 20 1.748 0.593 -14.187 1.00 0.50 C +ATOM 159 C PRO A 20 0.239 0.494 -13.972 1.00 0.52 C +ATOM 160 CB PRO A 20 2.250 -0.555 -15.067 1.00 0.49 C +ATOM 161 O PRO A 20 -0.239 -0.467 -13.363 1.00 0.51 O +ATOM 162 CG PRO A 20 3.024 -1.436 -14.141 1.00 0.46 C +ATOM 163 CD PRO A 20 3.173 -0.730 -12.824 1.00 0.46 C +ATOM 164 N LEU A 21 -0.387 1.673 -13.561 1.00 0.49 N +ATOM 165 CA LEU A 21 -1.840 1.543 -13.546 1.00 0.49 C +ATOM 166 C LEU A 21 -2.334 0.805 -14.786 1.00 0.49 C +ATOM 167 CB LEU A 21 -2.501 2.921 -13.461 1.00 0.47 C +ATOM 168 O LEU A 21 -3.422 0.225 -14.776 1.00 0.48 O +ATOM 169 CG LEU A 21 -2.547 3.567 -12.075 1.00 0.45 C +ATOM 170 CD1 LEU A 21 -2.511 5.087 -12.197 1.00 0.41 C +ATOM 171 CD2 LEU A 21 -3.791 3.116 -11.316 1.00 0.42 C +ATOM 172 N GLU A 22 -1.284 0.823 -15.746 1.00 0.49 N +ATOM 173 CA GLU A 22 -1.690 0.325 -17.056 1.00 0.49 C +ATOM 174 C GLU A 22 -1.183 -1.095 -17.289 1.00 0.49 C +ATOM 175 CB GLU A 22 -1.184 1.252 -18.164 1.00 0.45 C +ATOM 176 O GLU A 22 -1.105 -1.553 -18.431 1.00 0.47 O +ATOM 177 CG GLU A 22 -1.870 2.611 -18.191 1.00 0.43 C +ATOM 178 CD GLU A 22 -1.638 3.375 -19.484 1.00 0.46 C +ATOM 179 OE1 GLU A 22 -0.921 2.862 -20.372 1.00 0.44 O +ATOM 180 OE2 GLU A 22 -2.176 4.498 -19.610 1.00 0.40 O +ATOM 181 N SER A 23 -0.507 -1.685 -16.243 1.00 0.48 N +ATOM 182 CA SER A 23 -0.409 -3.087 -16.636 1.00 0.47 C +ATOM 183 C SER A 23 -1.772 -3.771 -16.589 1.00 0.48 C +ATOM 184 CB SER A 23 0.575 -3.830 -15.732 1.00 0.45 C +ATOM 185 O SER A 23 -2.460 -3.724 -15.568 1.00 0.46 O +ATOM 186 OG SER A 23 0.373 -3.480 -14.374 1.00 0.42 O +ATOM 187 N LYS A 24 -2.783 -3.245 -17.333 1.00 0.48 N +ATOM 188 CA LYS A 24 -3.816 -4.243 -17.597 1.00 0.47 C +ATOM 189 C LYS A 24 -3.258 -5.658 -17.476 1.00 0.48 C +ATOM 190 CB LYS A 24 -4.420 -4.035 -18.987 1.00 0.46 C +ATOM 191 O LYS A 24 -2.311 -6.020 -18.177 1.00 0.46 O +ATOM 192 CG LYS A 24 -5.249 -2.766 -19.119 1.00 0.44 C +ATOM 193 CD LYS A 24 -6.028 -2.741 -20.427 1.00 0.46 C +ATOM 194 CE LYS A 24 -6.820 -1.449 -20.582 1.00 0.40 C +ATOM 195 NZ LYS A 24 -7.573 -1.413 -21.871 1.00 0.37 N +ATOM 196 N PRO A 25 -3.101 -6.132 -16.224 1.00 0.48 N +ATOM 197 CA PRO A 25 -2.777 -7.561 -16.224 1.00 0.47 C +ATOM 198 C PRO A 25 -3.419 -8.311 -17.389 1.00 0.49 C +ATOM 199 CB PRO A 25 -3.336 -8.049 -14.886 1.00 0.46 C +ATOM 200 O PRO A 25 -4.457 -7.887 -17.905 1.00 0.48 O +ATOM 201 CG PRO A 25 -4.170 -6.915 -14.383 1.00 0.44 C +ATOM 202 CD PRO A 25 -3.916 -5.715 -15.250 1.00 0.45 C +ATOM 203 N GLU A 26 -2.595 -8.749 -18.537 1.00 0.52 N +ATOM 204 CA GLU A 26 -3.262 -9.728 -19.391 1.00 0.52 C +ATOM 205 C GLU A 26 -4.559 -10.221 -18.756 1.00 0.52 C +ATOM 206 CB GLU A 26 -2.334 -10.911 -19.678 1.00 0.49 C +ATOM 207 O GLU A 26 -4.681 -10.258 -17.530 1.00 0.50 O +ATOM 208 CG GLU A 26 -1.229 -10.598 -20.678 1.00 0.48 C +ATOM 209 CD GLU A 26 -0.782 -11.811 -21.477 1.00 0.50 C +ATOM 210 OE1 GLU A 26 -1.195 -12.945 -21.142 1.00 0.51 O +ATOM 211 OE2 GLU A 26 -0.012 -11.627 -22.446 1.00 0.47 O +ATOM 212 N PRO A 27 -5.776 -9.853 -19.347 1.00 0.50 N +ATOM 213 CA PRO A 27 -6.879 -10.502 -18.634 1.00 0.49 C +ATOM 214 C PRO A 27 -6.418 -11.681 -17.781 1.00 0.50 C +ATOM 215 CB PRO A 27 -7.800 -10.971 -19.763 1.00 0.47 C +ATOM 216 O PRO A 27 -5.769 -12.599 -18.290 1.00 0.49 O +ATOM 217 CG PRO A 27 -7.065 -10.637 -21.020 1.00 0.45 C +ATOM 218 CD PRO A 27 -5.782 -9.947 -20.654 1.00 0.45 C +ATOM 219 N VAL A 28 -5.550 -11.387 -16.664 1.00 0.49 N +ATOM 220 CA VAL A 28 -5.461 -12.521 -15.750 1.00 0.48 C +ATOM 221 C VAL A 28 -6.814 -13.223 -15.665 1.00 0.49 C +ATOM 222 CB VAL A 28 -4.999 -12.081 -14.343 1.00 0.47 C +ATOM 223 O VAL A 28 -7.852 -12.571 -15.529 1.00 0.48 O +ATOM 224 CG1 VAL A 28 -4.676 -13.297 -13.476 1.00 0.45 C +ATOM 225 CG2 VAL A 28 -3.787 -11.157 -14.445 1.00 0.46 C +ATOM 226 N GLN A 29 -7.108 -14.082 -16.749 1.00 0.53 N +ATOM 227 CA GLN A 29 -8.211 -15.035 -16.676 1.00 0.53 C +ATOM 228 C GLN A 29 -8.987 -14.878 -15.372 1.00 0.53 C +ATOM 229 CB GLN A 29 -7.692 -16.467 -16.810 1.00 0.48 C +ATOM 230 O GLN A 29 -8.402 -14.913 -14.287 1.00 0.51 O +ATOM 231 CG GLN A 29 -7.428 -16.894 -18.247 1.00 0.46 C +ATOM 232 CD GLN A 29 -7.062 -18.362 -18.366 1.00 0.48 C +ATOM 233 NE2 GLN A 29 -6.750 -18.799 -19.581 1.00 0.41 N +ATOM 234 OE1 GLN A 29 -7.058 -19.097 -17.373 1.00 0.50 O +ATOM 235 N GLY A 30 -9.845 -13.707 -15.208 1.00 0.58 N +ATOM 236 CA GLY A 30 -11.064 -13.567 -14.428 1.00 0.57 C +ATOM 237 C GLY A 30 -10.991 -12.454 -13.400 1.00 0.58 C +ATOM 238 O GLY A 30 -9.936 -12.218 -12.807 1.00 0.55 O +ATOM 239 N ALA A 31 -11.469 -11.174 -13.727 1.00 0.65 N +ATOM 240 CA ALA A 31 -11.865 -10.061 -12.868 1.00 0.64 C +ATOM 241 C ALA A 31 -11.715 -10.426 -11.394 1.00 0.65 C +ATOM 242 CB ALA A 31 -13.303 -9.645 -13.166 1.00 0.61 C +ATOM 243 O ALA A 31 -11.286 -9.600 -10.584 1.00 0.65 O +ATOM 244 N ALA A 32 -12.034 -11.668 -11.139 1.00 0.68 N +ATOM 245 CA ALA A 32 -11.937 -12.088 -9.744 1.00 0.67 C +ATOM 246 C ALA A 32 -10.490 -12.054 -9.260 1.00 0.68 C +ATOM 247 CB ALA A 32 -12.521 -13.487 -9.567 1.00 0.64 C +ATOM 248 O ALA A 32 -10.211 -11.605 -8.146 1.00 0.67 O +ATOM 249 N LEU A 33 -9.591 -12.548 -10.047 1.00 0.67 N +ATOM 250 CA LEU A 33 -8.192 -12.557 -9.631 1.00 0.66 C +ATOM 251 C LEU A 33 -7.660 -11.135 -9.484 1.00 0.67 C +ATOM 252 CB LEU A 33 -7.339 -13.332 -10.638 1.00 0.63 C +ATOM 253 O LEU A 33 -6.890 -10.849 -8.564 1.00 0.65 O +ATOM 254 CG LEU A 33 -5.950 -13.761 -10.161 1.00 0.59 C +ATOM 255 CD1 LEU A 33 -6.019 -15.128 -9.488 1.00 0.54 C +ATOM 256 CD2 LEU A 33 -4.967 -13.783 -11.326 1.00 0.55 C +ATOM 257 N GLN A 34 -8.043 -10.287 -10.357 1.00 0.68 N +ATOM 258 CA GLN A 34 -7.625 -8.892 -10.272 1.00 0.68 C +ATOM 259 C GLN A 34 -8.075 -8.262 -8.957 1.00 0.69 C +ATOM 260 CB GLN A 34 -8.176 -8.093 -11.454 1.00 0.65 C +ATOM 261 O GLN A 34 -7.304 -7.552 -8.307 1.00 0.68 O +ATOM 262 CG GLN A 34 -7.476 -6.759 -11.674 1.00 0.61 C +ATOM 263 CD GLN A 34 -7.961 -6.040 -12.920 1.00 0.59 C +ATOM 264 NE2 GLN A 34 -7.359 -4.893 -13.214 1.00 0.48 N +ATOM 265 OE1 GLN A 34 -8.868 -6.513 -13.612 1.00 0.55 O +ATOM 266 N ALA A 35 -9.311 -8.425 -8.724 1.00 0.72 N +ATOM 267 CA ALA A 35 -9.858 -7.851 -7.498 1.00 0.71 C +ATOM 268 C ALA A 35 -9.115 -8.371 -6.270 1.00 0.73 C +ATOM 269 CB ALA A 35 -11.348 -8.161 -7.384 1.00 0.70 C +ATOM 270 O ALA A 35 -8.849 -7.616 -5.332 1.00 0.73 O +ATOM 271 N GLU A 36 -8.800 -9.602 -6.322 1.00 0.75 N +ATOM 272 CA GLU A 36 -8.080 -10.212 -5.208 1.00 0.75 C +ATOM 273 C GLU A 36 -6.689 -9.603 -5.050 1.00 0.76 C +ATOM 274 CB GLU A 36 -7.971 -11.726 -5.403 1.00 0.73 C +ATOM 275 O GLU A 36 -6.256 -9.313 -3.933 1.00 0.75 O +ATOM 276 CG GLU A 36 -7.373 -12.458 -4.210 1.00 0.68 C +ATOM 277 CD GLU A 36 -7.447 -13.972 -4.336 1.00 0.65 C +ATOM 278 OE1 GLU A 36 -8.001 -14.471 -5.342 1.00 0.64 O +ATOM 279 OE2 GLU A 36 -6.948 -14.664 -3.421 1.00 0.59 O +ATOM 280 N LEU A 37 -5.986 -9.435 -6.129 1.00 0.74 N +ATOM 281 CA LEU A 37 -4.628 -8.906 -6.060 1.00 0.73 C +ATOM 282 C LEU A 37 -4.630 -7.469 -5.549 1.00 0.74 C +ATOM 283 CB LEU A 37 -3.957 -8.970 -7.435 1.00 0.71 C +ATOM 284 O LEU A 37 -3.797 -7.100 -4.718 1.00 0.73 O +ATOM 285 CG LEU A 37 -3.472 -10.348 -7.888 1.00 0.66 C +ATOM 286 CD1 LEU A 37 -3.167 -10.337 -9.382 1.00 0.61 C +ATOM 287 CD2 LEU A 37 -2.244 -10.772 -7.090 1.00 0.61 C +ATOM 288 N LEU A 38 -5.626 -6.678 -6.066 1.00 0.73 N +ATOM 289 CA LEU A 38 -5.729 -5.296 -5.610 1.00 0.73 C +ATOM 290 C LEU A 38 -6.038 -5.238 -4.118 1.00 0.75 C +ATOM 291 CB LEU A 38 -6.811 -4.551 -6.397 1.00 0.71 C +ATOM 292 O LEU A 38 -5.501 -4.391 -3.401 1.00 0.75 O +ATOM 293 CG LEU A 38 -6.433 -4.102 -7.809 1.00 0.66 C +ATOM 294 CD1 LEU A 38 -7.679 -3.690 -8.586 1.00 0.60 C +ATOM 295 CD2 LEU A 38 -5.428 -2.956 -7.755 1.00 0.60 C +ATOM 296 N SER A 39 -6.898 -6.106 -3.777 1.00 0.77 N +ATOM 297 CA SER A 39 -7.237 -6.146 -2.358 1.00 0.77 C +ATOM 298 C SER A 39 -6.013 -6.466 -1.507 1.00 0.78 C +ATOM 299 CB SER A 39 -8.333 -7.179 -2.098 1.00 0.75 C +ATOM 300 O SER A 39 -5.816 -5.871 -0.445 1.00 0.78 O +ATOM 301 OG SER A 39 -8.631 -7.259 -0.715 1.00 0.68 O +ATOM 302 N GLN A 40 -5.194 -7.402 -1.959 1.00 0.76 N +ATOM 303 CA GLN A 40 -4.005 -7.786 -1.205 1.00 0.76 C +ATOM 304 C GLN A 40 -3.014 -6.629 -1.113 1.00 0.76 C +ATOM 305 CB GLN A 40 -3.334 -9.003 -1.843 1.00 0.73 C +ATOM 306 O GLN A 40 -2.433 -6.384 -0.054 1.00 0.76 O +ATOM 307 CG GLN A 40 -4.050 -10.317 -1.563 1.00 0.66 C +ATOM 308 CD GLN A 40 -3.515 -11.466 -2.398 1.00 0.63 C +ATOM 309 NE2 GLN A 40 -4.359 -12.462 -2.645 1.00 0.54 N +ATOM 310 OE1 GLN A 40 -2.354 -11.457 -2.820 1.00 0.60 O +ATOM 311 N VAL A 41 -2.792 -5.944 -2.237 1.00 0.75 N +ATOM 312 CA VAL A 41 -1.862 -4.820 -2.237 1.00 0.74 C +ATOM 313 C VAL A 41 -2.341 -3.752 -1.256 1.00 0.75 C +ATOM 314 CB VAL A 41 -1.704 -4.213 -3.649 1.00 0.73 C +ATOM 315 O VAL A 41 -1.550 -3.215 -0.478 1.00 0.74 O +ATOM 316 CG1 VAL A 41 -0.947 -2.888 -3.586 1.00 0.65 C +ATOM 317 CG2 VAL A 41 -0.989 -5.196 -4.575 1.00 0.66 C +ATOM 318 N ARG A 42 -3.621 -3.448 -1.361 1.00 0.76 N +ATOM 319 CA ARG A 42 -4.187 -2.474 -0.434 1.00 0.76 C +ATOM 320 C ARG A 42 -3.930 -2.881 1.013 1.00 0.77 C +ATOM 321 CB ARG A 42 -5.690 -2.314 -0.673 1.00 0.74 C +ATOM 322 O ARG A 42 -3.588 -2.042 1.849 1.00 0.77 O +ATOM 323 CG ARG A 42 -6.034 -1.420 -1.855 1.00 0.69 C +ATOM 324 CD ARG A 42 -7.539 -1.280 -2.036 1.00 0.65 C +ATOM 325 NE ARG A 42 -7.867 -0.358 -3.120 1.00 0.59 N +ATOM 326 NH1 ARG A 42 -10.131 -0.814 -3.100 1.00 0.49 N +ATOM 327 NH2 ARG A 42 -9.276 0.705 -4.589 1.00 0.45 N +ATOM 328 CZ ARG A 42 -9.091 -0.158 -3.601 1.00 0.59 C +ATOM 329 N GLN A 43 -4.215 -4.159 1.316 1.00 0.78 N +ATOM 330 CA GLN A 43 -4.020 -4.652 2.675 1.00 0.78 C +ATOM 331 C GLN A 43 -2.557 -4.540 3.096 1.00 0.78 C +ATOM 332 CB GLN A 43 -4.490 -6.103 2.793 1.00 0.76 C +ATOM 333 O GLN A 43 -2.260 -4.175 4.235 1.00 0.77 O +ATOM 334 CG GLN A 43 -4.504 -6.630 4.222 1.00 0.70 C +ATOM 335 CD GLN A 43 -5.452 -5.861 5.123 1.00 0.66 C +ATOM 336 NE2 GLN A 43 -4.992 -5.534 6.326 1.00 0.60 N +ATOM 337 OE1 GLN A 43 -6.588 -5.562 4.740 1.00 0.66 O +ATOM 338 N ASP A 44 -1.615 -4.885 2.249 1.00 0.76 N +ATOM 339 CA ASP A 44 -0.192 -4.815 2.566 1.00 0.75 C +ATOM 340 C ASP A 44 0.231 -3.383 2.883 1.00 0.75 C +ATOM 341 CB ASP A 44 0.643 -5.366 1.409 1.00 0.73 C +ATOM 342 O ASP A 44 1.022 -3.152 3.800 1.00 0.74 O +ATOM 343 CG ASP A 44 0.532 -6.874 1.262 1.00 0.68 C +ATOM 344 OD1 ASP A 44 0.048 -7.544 2.199 1.00 0.65 O +ATOM 345 OD2 ASP A 44 0.935 -7.396 0.200 1.00 0.66 O +ATOM 346 N ILE A 45 -0.307 -2.445 2.112 1.00 0.76 N +ATOM 347 CA ILE A 45 -0.006 -1.042 2.371 1.00 0.75 C +ATOM 348 C ILE A 45 -0.514 -0.652 3.758 1.00 0.76 C +ATOM 349 CB ILE A 45 -0.625 -0.122 1.295 1.00 0.73 C +ATOM 350 O ILE A 45 0.201 -0.011 4.531 1.00 0.75 O +ATOM 351 CG1 ILE A 45 0.082 -0.322 -0.050 1.00 0.67 C +ATOM 352 CG2 ILE A 45 -0.561 1.343 1.735 1.00 0.67 C +ATOM 353 CD1 ILE A 45 -0.609 0.363 -1.221 1.00 0.64 C +ATOM 354 N ALA A 46 -1.744 -0.973 3.967 1.00 0.76 N +ATOM 355 CA ALA A 46 -2.318 -0.646 5.269 1.00 0.75 C +ATOM 356 C ALA A 46 -1.481 -1.235 6.401 1.00 0.76 C +ATOM 357 CB ALA A 46 -3.757 -1.149 5.358 1.00 0.74 C +ATOM 358 O ALA A 46 -1.239 -0.572 7.413 1.00 0.75 O +ATOM 359 N ASN A 47 -1.100 -2.513 6.275 1.00 0.77 N +ATOM 360 CA ASN A 47 -0.287 -3.170 7.293 1.00 0.76 C +ATOM 361 C ASN A 47 1.046 -2.456 7.493 1.00 0.75 C +ATOM 362 CB ASN A 47 -0.053 -4.638 6.927 1.00 0.74 C +ATOM 363 O ASN A 47 1.503 -2.291 8.626 1.00 0.74 O +ATOM 364 CG ASN A 47 -1.313 -5.474 7.032 1.00 0.70 C +ATOM 365 ND2 ASN A 47 -1.301 -6.646 6.410 1.00 0.68 N +ATOM 366 OD1 ASN A 47 -2.291 -5.068 7.666 1.00 0.70 O +ATOM 367 N SER A 48 1.642 -2.096 6.364 1.00 0.75 N +ATOM 368 CA SER A 48 2.925 -1.406 6.457 1.00 0.73 C +ATOM 369 C SER A 48 2.787 -0.078 7.194 1.00 0.73 C +ATOM 370 CB SER A 48 3.508 -1.167 5.064 1.00 0.71 C +ATOM 371 O SER A 48 3.641 0.278 8.009 1.00 0.70 O +ATOM 372 OG SER A 48 3.811 -2.397 4.427 1.00 0.65 O +ATOM 373 N LEU A 49 1.734 0.640 6.845 1.00 0.72 N +ATOM 374 CA LEU A 49 1.508 1.919 7.510 1.00 0.72 C +ATOM 375 C LEU A 49 1.271 1.721 9.003 1.00 0.72 C +ATOM 376 CB LEU A 49 0.315 2.645 6.884 1.00 0.70 C +ATOM 377 O LEU A 49 1.763 2.499 9.823 1.00 0.71 O +ATOM 378 CG LEU A 49 0.534 3.228 5.487 1.00 0.66 C +ATOM 379 CD1 LEU A 49 -0.788 3.717 4.904 1.00 0.61 C +ATOM 380 CD2 LEU A 49 1.554 4.360 5.533 1.00 0.62 C +ATOM 381 N ASN A 50 0.475 0.748 9.327 1.00 0.74 N +ATOM 382 CA ASN A 50 0.188 0.475 10.732 1.00 0.73 C +ATOM 383 C ASN A 50 1.452 0.099 11.499 1.00 0.73 C +ATOM 384 CB ASN A 50 -0.860 -0.633 10.860 1.00 0.70 C +ATOM 385 O ASN A 50 1.622 0.493 12.654 1.00 0.71 O +ATOM 386 CG ASN A 50 -2.278 -0.113 10.732 1.00 0.65 C +ATOM 387 ND2 ASN A 50 -3.214 -1.008 10.440 1.00 0.63 N +ATOM 388 OD1 ASN A 50 -2.530 1.084 10.892 1.00 0.63 O +ATOM 389 N ALA A 51 2.296 -0.751 10.857 1.00 0.70 N +ATOM 390 CA ALA A 51 3.518 -1.202 11.518 1.00 0.69 C +ATOM 391 C ALA A 51 4.408 -0.020 11.892 1.00 0.68 C +ATOM 392 CB ALA A 51 4.279 -2.175 10.622 1.00 0.67 C +ATOM 393 O ALA A 51 5.038 -0.020 12.952 1.00 0.67 O +ATOM 394 N VAL A 52 4.525 0.951 11.010 1.00 0.67 N +ATOM 395 CA VAL A 52 5.352 2.120 11.288 1.00 0.66 C +ATOM 396 C VAL A 52 4.723 2.942 12.411 1.00 0.65 C +ATOM 397 CB VAL A 52 5.540 2.995 10.029 1.00 0.63 C +ATOM 398 O VAL A 52 5.431 3.495 13.256 1.00 0.64 O +ATOM 399 CG1 VAL A 52 6.261 4.296 10.378 1.00 0.57 C +ATOM 400 CG2 VAL A 52 6.309 2.226 8.956 1.00 0.58 C +ATOM 401 N ALA A 53 3.415 3.071 12.338 1.00 0.62 N +ATOM 402 CA ALA A 53 2.746 3.869 13.362 1.00 0.60 C +ATOM 403 C ALA A 53 2.961 3.272 14.750 1.00 0.61 C +ATOM 404 CB ALA A 53 1.253 3.980 13.059 1.00 0.58 C +ATOM 405 O ALA A 53 2.919 3.988 15.753 1.00 0.61 O +ATOM 406 N THR A 54 3.105 1.936 14.815 1.00 0.61 N +ATOM 407 CA THR A 54 3.158 1.297 16.126 1.00 0.61 C +ATOM 408 C THR A 54 4.591 1.253 16.648 1.00 0.61 C +ATOM 409 CB THR A 54 2.583 -0.131 16.075 1.00 0.57 C +ATOM 410 O THR A 54 4.835 0.805 17.770 1.00 0.59 O +ATOM 411 CG2 THR A 54 1.101 -0.114 15.712 1.00 0.51 C +ATOM 412 OG1 THR A 54 3.295 -0.892 15.092 1.00 0.54 O +ATOM 413 N ARG A 55 5.532 1.631 15.809 1.00 0.65 N +ATOM 414 CA ARG A 55 6.903 1.567 16.303 1.00 0.65 C +ATOM 415 C ARG A 55 7.118 2.544 17.453 1.00 0.65 C +ATOM 416 CB ARG A 55 7.895 1.859 15.175 1.00 0.61 C +ATOM 417 O ARG A 55 6.621 3.672 17.418 1.00 0.63 O +ATOM 418 CG ARG A 55 8.075 0.707 14.199 1.00 0.59 C +ATOM 419 CD ARG A 55 9.132 1.017 13.148 1.00 0.59 C +ATOM 420 NE ARG A 55 9.264 -0.067 12.180 1.00 0.52 N +ATOM 421 NH1 ARG A 55 10.992 0.916 11.004 1.00 0.41 N +ATOM 422 NH2 ARG A 55 10.179 -1.128 10.359 1.00 0.36 N +ATOM 423 CZ ARG A 55 10.145 -0.090 11.183 1.00 0.55 C +ATOM 424 N PRO A 56 7.605 2.129 18.545 1.00 0.62 N +ATOM 425 CA PRO A 56 7.968 3.039 19.634 1.00 0.61 C +ATOM 426 C PRO A 56 8.765 4.249 19.151 1.00 0.62 C +ATOM 427 CB PRO A 56 8.815 2.161 20.559 1.00 0.56 C +ATOM 428 O PRO A 56 9.656 4.109 18.310 1.00 0.59 O +ATOM 429 CG PRO A 56 8.612 0.769 20.056 1.00 0.53 C +ATOM 430 CD PRO A 56 8.067 0.841 18.659 1.00 0.55 C +ATOM 431 N GLY A 57 8.356 5.535 19.374 1.00 0.58 N +ATOM 432 CA GLY A 57 8.945 6.814 19.010 1.00 0.58 C +ATOM 433 C GLY A 57 8.368 7.395 17.733 1.00 0.58 C +ATOM 434 O GLY A 57 8.738 8.497 17.323 1.00 0.57 O +ATOM 435 N TYR A 58 7.679 6.470 16.960 1.00 0.54 N +ATOM 436 CA TYR A 58 7.100 7.135 15.799 1.00 0.54 C +ATOM 437 C TYR A 58 6.095 8.199 16.224 1.00 0.53 C +ATOM 438 CB TYR A 58 6.422 6.116 14.878 1.00 0.50 C +ATOM 439 O TYR A 58 6.065 9.295 15.659 1.00 0.52 O +ATOM 440 CG TYR A 58 6.176 6.630 13.480 1.00 0.49 C +ATOM 441 CD1 TYR A 58 4.946 7.177 13.124 1.00 0.47 C +ATOM 442 CD2 TYR A 58 7.173 6.568 12.512 1.00 0.48 C +ATOM 443 CE1 TYR A 58 4.714 7.650 11.837 1.00 0.47 C +ATOM 444 CE2 TYR A 58 6.953 7.038 11.222 1.00 0.48 C +ATOM 445 OH TYR A 58 5.498 8.043 9.618 1.00 0.44 O +ATOM 446 CZ TYR A 58 5.722 7.577 10.894 1.00 0.46 C +ATOM 447 N LEU A 59 5.154 7.928 17.166 1.00 0.50 N +ATOM 448 CA LEU A 59 4.166 8.868 17.683 1.00 0.50 C +ATOM 449 C LEU A 59 4.547 9.344 19.081 1.00 0.50 C +ATOM 450 CB LEU A 59 2.777 8.224 17.711 1.00 0.47 C +ATOM 451 O LEU A 59 3.832 10.147 19.684 1.00 0.49 O +ATOM 452 CG LEU A 59 2.130 7.949 16.353 1.00 0.45 C +ATOM 453 CD1 LEU A 59 0.903 7.059 16.521 1.00 0.42 C +ATOM 454 CD2 LEU A 59 1.756 9.257 15.663 1.00 0.44 C +ATOM 455 N ALA A 60 5.718 9.319 19.497 1.00 0.46 N +ATOM 456 CA ALA A 60 6.022 9.769 20.853 1.00 0.46 C +ATOM 457 C ALA A 60 7.279 10.633 20.876 1.00 0.46 C +ATOM 458 CB ALA A 60 6.186 8.572 21.787 1.00 0.42 C +ATOM 459 O ALA A 60 8.383 10.140 20.637 1.00 0.44 O +ATOM 460 N GLY A 61 7.357 11.746 20.071 1.00 0.45 N +ATOM 461 CA GLY A 61 8.144 12.780 20.724 1.00 0.45 C +ATOM 462 C GLY A 61 7.607 14.179 20.487 1.00 0.46 C +ATOM 463 O GLY A 61 7.660 14.688 19.366 1.00 0.44 O +ATOM 464 N GLY A 62 6.464 14.557 21.219 1.00 0.33 N +ATOM 465 CA GLY A 62 6.288 15.850 21.860 1.00 0.36 C +ATOM 466 C GLY A 62 7.363 16.852 21.487 1.00 0.33 C +ATOM 467 O GLY A 62 8.470 16.469 21.102 1.00 0.32 O \ No newline at end of file diff --git a/esm/mcp_output/requirements.txt b/esm/mcp_output/requirements.txt new file mode 100644 index 0000000000000000000000000000000000000000..8bf1c18c2fedf45ee4cdefcb4d781f81f311f2cb --- /dev/null +++ b/esm/mcp_output/requirements.txt @@ -0,0 +1,4 @@ +fastmcp>=0.1.0 +pydantic>=2.0.0 +requests +biopython diff --git a/esm/mcp_output/start_mcp.py b/esm/mcp_output/start_mcp.py new file mode 100644 index 0000000000000000000000000000000000000000..e677811af060521e9d5c25ec0645b47f6f2646e7 --- /dev/null +++ b/esm/mcp_output/start_mcp.py @@ -0,0 +1,34 @@ + +""" +MCP Service Startup Entry Point +""" +import sys +import os + +project_root = os.path.dirname(os.path.abspath(__file__)) +mcp_plugin_dir = os.path.join(project_root, "mcp_plugin") +if mcp_plugin_dir not in sys.path: + sys.path.insert(0, mcp_plugin_dir) + +# Set path to point to source directory +source_path = os.path.join(os.path.dirname(os.path.dirname(os.path.abspath(__file__))), "source") +sys.path.insert(0, source_path) + +from mcp_service import create_app + +def main(): + """Start FastMCP Service""" + app = create_app() + # Use environment variable to configure port, default 8000 + port = int(os.environ.get("MCP_PORT", "8000")) + + # Select transport mode based on environment variable + transport = os.environ.get("MCP_TRANSPORT", "stdio") + if transport == "http": + app.run(transport="http", host="0.0.0.0", port=port) + else: + # Default to STDIO mode + app.run() + +if __name__ == "__main__": + main() diff --git a/esm/mcp_output/tests_mcp/test_mcp_basic.py b/esm/mcp_output/tests_mcp/test_mcp_basic.py new file mode 100644 index 0000000000000000000000000000000000000000..18b705c2c741509b4ce6a150e099b0928b48fec8 --- /dev/null +++ b/esm/mcp_output/tests_mcp/test_mcp_basic.py @@ -0,0 +1,49 @@ +""" +MCP Service Basic Tests +""" +import sys +import os + +project_root = os.path.dirname(os.path.dirname(os.path.abspath(__file__))) +mcp_plugin_dir = os.path.join(project_root, "mcp_plugin") +if mcp_plugin_dir not in sys.path: + sys.path.insert(0, mcp_plugin_dir) + +source_path = os.path.join(os.path.dirname(os.path.dirname(os.path.dirname(os.path.abspath(__file__)))), "source") +sys.path.insert(0, source_path) + +def test_import_mcp_service(): + """Test that the MCP service can be imported correctly""" + try: + from mcp_service import create_app + app = create_app() + assert app is not None + print("MCP service imported successfully") + return True + except Exception as e: + print(f"Failed to import MCP service: {e}") + return False + +def test_adapter_init(): + """Test that the adapter can be initialized correctly""" + try: + from adapter import Adapter + adapter = Adapter() + assert adapter is not None + print("Adapter initialized successfully") + return True + except Exception as e: + print(f"Failed to initialize adapter: {e}") + return False + +if __name__ == "__main__": + print("Running MCP service basic tests...") + test1 = test_import_mcp_service() + test2 = test_adapter_init() + + if test1 and test2: + print("All basic tests passed") + sys.exit(0) + else: + print("Some tests failed") + sys.exit(1) \ No newline at end of file diff --git a/esm/mcp_output/tests_smoke/test_smoke.py b/esm/mcp_output/tests_smoke/test_smoke.py new file mode 100644 index 0000000000000000000000000000000000000000..3ae737e49008bf9b6a77bbc17f2363d18e91bd80 --- /dev/null +++ b/esm/mcp_output/tests_smoke/test_smoke.py @@ -0,0 +1,29 @@ +import importlib, sys +import os + +# Add current directory to Python path +sys.path.insert(0, os.getcwd()) + +source_dir = os.path.join(os.getcwd(), "source") +if os.path.exists(source_dir): + sys.path.insert(0, source_dir) + + +try: + importlib.import_module("esm") + print("OK - Successfully imported esm") +except ImportError as e: + print(f"Failed to import esm: {e}") + fallback_packages = [] + + fallback_packages = ['esm'] + + for pkg in fallback_packages: + try: + importlib.import_module(pkg) + print(f"OK - Successfully imported {pkg}") + break + except ImportError: + continue + else: + print("All import attempts failed") \ No newline at end of file diff --git a/esm/source/.flake8 b/esm/source/.flake8 new file mode 100644 index 0000000000000000000000000000000000000000..fa3edf250ca4c596bc5b7a790227487f4b54aacb --- /dev/null +++ b/esm/source/.flake8 @@ -0,0 +1,10 @@ +[flake8] +max-line-length = 99 +ignore = E203,W503 +exclude = + .git, + __pycache__, + build, + dist, + experimental + third_party diff --git a/esm/source/.git-blame-ignore-revs b/esm/source/.git-blame-ignore-revs new file mode 100644 index 0000000000000000000000000000000000000000..b9a5aa409343d406601286060793754a1eb3cd65 --- /dev/null +++ b/esm/source/.git-blame-ignore-revs @@ -0,0 +1,2 @@ +# Migrate code style to Black +8bc7e948cd9bf0b6d1f2113e221ef548ef663377 diff --git a/esm/source/.github/ISSUE_TEMPLATE/bug.md b/esm/source/.github/ISSUE_TEMPLATE/bug.md new file mode 100644 index 0000000000000000000000000000000000000000..14e5b659fc66ce5ff5963e291e30d49a42795dd7 --- /dev/null +++ b/esm/source/.github/ISSUE_TEMPLATE/bug.md @@ -0,0 +1,27 @@ +--- +name: "[Bug Report]" +about: "Create a bug report. For other questions: see Discussions tab." + +--- + +NOTE: if this is not a bug report, please use the [GitHub Discussions](https://github.com/facebookresearch/esm/discussions) for support questions (How do I do X?), feature requests, ideas, showcasing new applications, etc. + + +**Bug description** +Please enter a clear and concise description of what the bug is. + +**Reproduction steps** +Enter steps to reproduce the behavior. + +**Expected behavior** +Give a clear and concise description of what you expected to happen. + +**Logs** +Please paste the command line output: + +``` +Output goes here +``` + +**Additional context** +Add any other context about the problem here. (like proxy settings, network setup, overall goals, etc.) diff --git a/esm/source/.gitignore b/esm/source/.gitignore new file mode 100644 index 0000000000000000000000000000000000000000..722d88b393bf5a921e858811ec32114da9fb057e --- /dev/null +++ b/esm/source/.gitignore @@ -0,0 +1,31 @@ +# tensor dumps +*.pt +# Compiler Output # +################### +*.py[cod] +*.so +*.o +*.exe +*.class + +# Folders # +########### +bin/ +build/ +dist/ +local/ +tmp/ +__pycache__/ +*.egg-info/ +.idea/ +.ipynb_checkpoints/ +.vscode/ +esm/dev + +# Junk # +######## +.DS_Store* +.*.swp +*.swp +*.log +*~ diff --git a/esm/source/CODE_OF_CONDUCT.rst b/esm/source/CODE_OF_CONDUCT.rst new file mode 100644 index 0000000000000000000000000000000000000000..f7367ec7c1f069fc2263feceda79041bf01980ae --- /dev/null +++ b/esm/source/CODE_OF_CONDUCT.rst @@ -0,0 +1,6 @@ +Code of Conduct +=============== + +Facebook has adopted a Code of Conduct that we expect project participants to adhere to. Please `read the full text`__ so that you can understand what actions will and will not be tolerated. + +__ https://code.facebook.com/codeofconduct diff --git a/esm/source/CONTRIBUTING.md b/esm/source/CONTRIBUTING.md new file mode 100644 index 0000000000000000000000000000000000000000..9d6a6cc5b628ddaefd4e1970d406df20abd1f3e1 --- /dev/null +++ b/esm/source/CONTRIBUTING.md @@ -0,0 +1,31 @@ +# Contributing to esm +We want to make contributing to this project as easy and transparent as +possible. + +## Pull Requests +We actively welcome your pull requests. + +1. Fork the repo and create your branch from `master`. +2. If you've added code that should be tested, add tests. +3. If you've changed APIs, update the documentation. +4. Ensure the test suite passes. +5. Make sure your code lints. +6. If you haven't already, complete the Contributor License Agreement ("CLA"). + +## Contributor License Agreement ("CLA") +In order to accept your pull request, we need you to submit a CLA. You only need +to do this once to work on any of Facebook's open source projects. + +Complete your CLA here: + +## Issues +We use GitHub issues to track public bugs. Please ensure your description is +clear and has sufficient instructions to be able to reproduce the issue. + +Facebook has a [bounty program](https://www.facebook.com/whitehat/) for the safe +disclosure of security bugs. In those cases, please go through the process +outlined on that page and do not file a public issue. + +## License +By contributing to icp-block-mdp, you agree that your contributions will be licensed +under the LICENSE file in the root directory of this source tree. diff --git a/esm/source/LICENSE b/esm/source/LICENSE new file mode 100644 index 0000000000000000000000000000000000000000..b93be90515ccd0b9daedaa589e42bf5929693f1f --- /dev/null +++ b/esm/source/LICENSE @@ -0,0 +1,21 @@ +MIT License + +Copyright (c) Meta Platforms, Inc. and affiliates. + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in all +copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE +SOFTWARE. diff --git a/esm/source/README.md b/esm/source/README.md new file mode 100644 index 0000000000000000000000000000000000000000..7b19e716fd6a14c3c810d804a33c63aa099a505b --- /dev/null +++ b/esm/source/README.md @@ -0,0 +1,795 @@ +# Evolutionary Scale Modeling + +[![atlas](https://user-images.githubusercontent.com/3605224/199301187-a9e38b3f-71a7-44be-94f4-db0d66143c53.png)](https://esmatlas.com) + +***Update April 2023:*** Code for the two simultaneous preprints on protein design is now released! Code for "Language models generalize beyond natural proteins" is under [examples/lm-design/](examples/lm-design/). Code for "A high-level programming language for generative protein design" is under [examples/protein-programming-language/](examples/protein-programming-language/). + +This repository contains code and pre-trained weights for **Transformer protein language models** from the Meta Fundamental AI Research Protein Team (FAIR), including our state-of-the-art [**ESM-2** and **ESMFold**](#esmfold), as well as [**MSA Transformer**](https://www.biorxiv.org/content/10.1101/2021.02.12.430858v1), [**ESM-1v**](#zs_variant) for predicting variant effects and [**ESM-IF1**](#invf) for inverse folding. +Transformer protein language models were introduced in the [2019 preprint](https://doi.org/10.1101/622803) of the paper ["Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences"](https://doi.org/10.1073/pnas.2016239118). +ESM-2 outperforms all tested single-sequence protein language models across a range of structure prediction tasks. +ESMFold harnesses the ESM-2 language model to generate accurate structure predictions end to end directly from the sequence of a protein. + +In November 2022, we released `v0` of the [ESM Metagenomic Atlas](https://esmatlas.com), an open atlas of 617 million predicted metagenomic protein structures. +The Atlas was updated in March 2023 in collaboration with EBI. The new `v2023_02` adds another 150 million predicted structures to the Atlas, as well as pre-computed ESM2 embeddings. +Bulk download, blog post and the resources provided on the Atlas website are documented [on this README](#atlas). + +In December 2022, we released two simultaneous preprints on protein design. +* "Language models generalize beyond natural proteins" ([PAPER](https://doi.org/10.1101/2022.12.21.521521), [CODE](examples/lm-design/)) uses ESM2 to design de novo proteins. The code and data associated with the preprint can be found [here](examples/lm-design/). +* "A high-level programming language for generative protein design" ([PAPER](https://doi.org/10.1101/2022.12.21.521526), [CODE](examples/protein-programming-language/)) uses ESMFold to design proteins according to a high-level programming language. + + + +
Citation +For ESM2, ESMFold and ESM Atlas: +```bibtex +@article{lin2023evolutionary, +title = {Evolutionary-scale prediction of atomic-level protein structure with a language model}, +author = {Zeming Lin and Halil Akin and Roshan Rao and Brian Hie and Zhongkai Zhu and Wenting Lu and Nikita Smetanin and Robert Verkuil and Ori Kabeli and Yaniv Shmueli and Allan dos Santos Costa and Maryam Fazel-Zarandi and Tom Sercu and Salvatore Candido and Alexander Rives }, +journal = {Science}, +volume = {379}, +number = {6637}, +pages = {1123-1130}, +year = {2023}, +doi = {10.1126/science.ade2574}, +URL = {https://www.science.org/doi/abs/10.1126/science.ade2574}, +note={Earlier versions as preprint: bioRxiv 2022.07.20.500902}, +} +``` + +For transformer protein language models: +```bibtex +@article{rives2021biological, + title={Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences}, + author={Rives, Alexander and Meier, Joshua and Sercu, Tom and Goyal, Siddharth and Lin, Zeming and Liu, Jason and Guo, Demi and Ott, Myle and Zitnick, C Lawrence and Ma, Jerry and others}, + journal={Proceedings of the National Academy of Sciences}, + volume={118}, + number={15}, + pages={e2016239118}, + year={2021}, + publisher={National Acad Sciences}, + note={bioRxiv 10.1101/622803}, + doi={10.1073/pnas.2016239118}, + url={https://www.pnas.org/doi/full/10.1073/pnas.2016239118}, +} +``` +
+ +
Table of contents + +- [Main models you should use](#main-models) +- [Usage](#usage) + - [Quick Start](#quickstart) + - [Getting Started with this repository](#repostart) + - [ESMFold Structure Prediction](#esmfold) + - [Compute embeddings in bulk from FASTA](#bulk_fasta) + - [CPU offloading for inference with large models](#fsdp) + - [Zero-shot variant prediction](#zs_variant) + - [Inverse folding](#invf) +- [ESM Metagenomic Atlas](#atlas) +- [Notebooks](#notebooks) +- [Available Models and Datasets](#available) + - [Pre-trained Models](#available-models) + - [ESM Structural Split Dataset](#available-esmssd) + - [Pre-training Dataset Split](#available-pretraining-split) + - [Comparison to related works](#perf_related) +- [Citations](#citations) +- [License](#license) +
+ +
What's New + +- April 2023: Code for the protein design preprints released under [examples/lm-design/](examples/lm-design/). +- March 2023: We release an update to the ESM Metagenomic Atlas, `v2023_02`. See [website](https://esmatlas.com/) and [bulk download details](#atlas). +- December 2022: The Meta Fundamental AI Research Protein Team (FAIR) released two simultaneous preprints on protein design: +["Language models generalize beyond natural proteins" (Verkuil, Kabeli, et al., 2022)](https://doi.org/10.1101/2022.12.21.521521), and ["A high-level programming language for generative protein design" (Hie, Candido, et al., 2022)](https://doi.org/10.1101/2022.12.21.521521). +- November 2022: ESM Metagenomic Atlas, a repository of 600M+ metagenomics structures released, see [website](https://esmatlas.com/) and [bulk download details](#atlas) +- November 2022: ESMFold - new end-to-end structure prediction model released (see [Lin et al. 2022](https://www.science.org/doi/abs/10.1126/science.ade2574)) +- August 2022: ESM-2 - new SOTA Language Models released (see [Lin et al. 2022](https://www.science.org/doi/abs/10.1126/science.ade2574)) +- April 2022: New inverse folding model ESM-IF1 released, trained on CATH and UniRef50 predicted structures. +- August 2021: Added flexibility to tokenizer to allow for spaces and special tokens (like ``) in sequence. +- July 2021: New pre-trained model ESM-1v released, trained on UniRef90 (see [Meier et al. 2021](https://doi.org/10.1101/2021.07.09.450648)). +- July 2021: New MSA Transformer released, with a minor fix in the row positional embeddings (`ESM-MSA-1b`). +- Feb 2021: MSA Transformer added (see [Rao et al. 2021](https://www.biorxiv.org/content/10.1101/2021.02.12.430858v1)). Example usage in [notebook](#notebooks). +- Dec 2020: [Self-Attention Contacts](#notebooks) for all pre-trained models (see [Rao et al. 2020](https://doi.org/10.1101/2020.12.15.422761)) +- Dec 2020: Added new pre-trained model [ESM-1b](#perf_related) (see [Rives et al. 2019](https://doi.org/10.1101/622803) Appendix B) +- Dec 2020: [ESM Structural Split Dataset](#available-esmssd) (see [Rives et al. 2019](https://doi.org/10.1101/622803) Appendix A.10) + +
+ +## Main models you should use + +| Shorthand | `esm.pretrained.` | Dataset | Description | +|-----------|-----------------------------|---------|--------------| +| ESM-2 | `esm2_t36_3B_UR50D()` `esm2_t48_15B_UR50D()` | UR50 (sample UR90) | SOTA general-purpose protein language model. Can be used to predict structure, function and other protein properties directly from individual sequences. Released with [Lin et al. 2022](https://www.science.org/doi/abs/10.1126/science.ade2574) (Aug 2022 update). | +| ESMFold | `esmfold_v1()` | PDB + UR50 | End-to-end single sequence 3D structure predictor (Nov 2022 update). | +| ESM-MSA-1b| `esm_msa1b_t12_100M_UR50S()` | UR50 + MSA | MSA Transformer language model. Can be used to extract embeddings from an MSA. Enables SOTA inference of structure. Released with [Rao et al. 2021](https://www.biorxiv.org/content/10.1101/2021.02.12.430858v2) (ICML'21 version, June 2021). | +| ESM-1v | `esm1v_t33_650M_UR90S_1()` ... `esm1v_t33_650M_UR90S_5()`| UR90 | Language model specialized for prediction of variant effects. Enables SOTA zero-shot prediction of the functional effects of sequence variations. Same architecture as ESM-1b, but trained on UniRef90. Released with [Meier et al. 2021](https://doi.org/10.1101/2021.07.09.450648). | +| ESM-IF1 | `esm_if1_gvp4_t16_142M_UR50()` | CATH + UR50 | Inverse folding model. Can be used to design sequences for given structures, or to predict functional effects of sequence variation for given structures. Enables SOTA fixed backbone sequence design. Released with [Hsu et al. 2022](https://doi.org/10.1101/2022.04.10.487779). | + +For a complete list of available models, with details and release notes, see [Pre-trained Models](#available-models). + + +## Usage + +### Quick start + +An easy way to get started is to load ESM or ESMFold through the [HuggingFace transformers library](https://huggingface.co/docs/transformers/model_doc/esm), +which has simplified the ESMFold dependencies and provides a standardized API and tools to work with state-of-the-art pretrained models. + +Alternatively, [ColabFold](https://colab.research.google.com/github/sokrypton/ColabFold/blob/main/ESMFold.ipynb) has integrated ESMFold so that you can +easily run it directly in the browser on a Google Colab instance. + +We also provide an API which you can access through curl or on [the ESM Metagenomic Atlas web page](https://esmatlas.com/resources?action=fold). +``` +curl -X POST --data "KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL" https://api.esmatlas.com/foldSequence/v1/pdb/ +``` + +For ESM-MSA-1b, ESM-IF1, or any of the other models you can use the original implementation from our repo directly via the instructions below. + +### Getting started with this repo + +As a prerequisite, you must have PyTorch installed to use this repository. + +You can use this one-liner for installation, using the latest release of esm: + +```bash +pip install fair-esm # latest release, OR: +pip install git+https://github.com/facebookresearch/esm.git # bleeding edge, current repo main branch +``` + +To use the ESMFold model, make sure you start from an environment with python <= 3.9 and pytorch installed. +Then add the `[esmfold]` option to your pip install, which will install the dependencies for OpenFold +automatically. Openfold installation requires `nvcc`. + +```bash +pip install "fair-esm[esmfold]" +# OpenFold and its remaining dependency +pip install 'dllogger @ git+https://github.com/NVIDIA/dllogger.git' +pip install 'openfold @ git+https://github.com/aqlaboratory/openfold.git@4b41059694619831a7db195b7e0988fc4ff3a307' +``` + +**NOTE**: If openfold installation fails, please double check that `nvcc` is available and that a cuda-compatable version of PyTorch has been installed. + +Alternatively, we provide the `esmfold` conda environment, which can be built via `conda env create -f environment.yml`. + +We also support PyTorch Hub, which removes the need to clone and/or install this repository yourself: + +```python +import torch +model, alphabet = torch.hub.load("facebookresearch/esm:main", "esm2_t33_650M_UR50D") +``` + +After pip install, you can load and use a pretrained model as follows: + +```python +import torch +import esm + +# Load ESM-2 model +model, alphabet = esm.pretrained.esm2_t33_650M_UR50D() +batch_converter = alphabet.get_batch_converter() +model.eval() # disables dropout for deterministic results + +# Prepare data (first 2 sequences from ESMStructuralSplitDataset superfamily / 4) +data = [ + ("protein1", "MKTVRQERLKSIVRILERSKEPVSGAQLAEELSVSRQVIVQDIAYLRSLGYNIVATPRGYVLAGG"), + ("protein2", "KALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEE"), + ("protein2 with mask","KALTARQQEVFDLIRDISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEE"), + ("protein3", "K A I S Q"), +] +batch_labels, batch_strs, batch_tokens = batch_converter(data) +batch_lens = (batch_tokens != alphabet.padding_idx).sum(1) + +# Extract per-residue representations (on CPU) +with torch.no_grad(): + results = model(batch_tokens, repr_layers=[33], return_contacts=True) +token_representations = results["representations"][33] + +# Generate per-sequence representations via averaging +# NOTE: token 0 is always a beginning-of-sequence token, so the first residue is token 1. +sequence_representations = [] +for i, tokens_len in enumerate(batch_lens): + sequence_representations.append(token_representations[i, 1 : tokens_len - 1].mean(0)) + +# Look at the unsupervised self-attention map contact predictions +import matplotlib.pyplot as plt +for (_, seq), tokens_len, attention_contacts in zip(data, batch_lens, results["contacts"]): + plt.matshow(attention_contacts[: tokens_len, : tokens_len]) + plt.title(seq) + plt.show() +``` + + +### ESMFold Structure Prediction + +After installing with the `[esmfold]` option, you can use the ESMFold structure prediction model as follows: + +```python +import torch +import esm + +model = esm.pretrained.esmfold_v1() +model = model.eval().cuda() + +# Optionally, uncomment to set a chunk size for axial attention. This can help reduce memory. +# Lower sizes will have lower memory requirements at the cost of increased speed. +# model.set_chunk_size(128) + +sequence = "MKTVRQERLKSIVRILERSKEPVSGAQLAEELSVSRQVIVQDIAYLRSLGYNIVATPRGYVLAGG" +# Multimer prediction can be done with chains separated by ':' + +with torch.no_grad(): + output = model.infer_pdb(sequence) + +with open("result.pdb", "w") as f: + f.write(output) + +import biotite.structure.io as bsio +struct = bsio.load_structure("result.pdb", extra_fields=["b_factor"]) +print(struct.b_factor.mean()) # this will be the pLDDT +# 88.3 +``` + + +Besides `esm.pretrained.esmfold_v1()` which is the best performing model we recommend using, we +also provide `esm.pretrained.esmfold_v0()` which was used for the experiments in +[Lin et al. 2022](https://www.science.org/doi/abs/10.1126/science.ade2574). + +We also provide a command line interface (`esm-fold`) that efficiently predicts structures in bulk from a FASTA file using ESMFold: +``` +usage: esm-fold [-h] -i FASTA -o PDB [--num-recycles NUM_RECYCLES] + [--max-tokens-per-batch MAX_TOKENS_PER_BATCH] + [--chunk-size CHUNK_SIZE] [--cpu-only] [--cpu-offload] + +optional arguments: + -h, --help show this help message and exit + -i FASTA, --fasta FASTA + Path to input FASTA file + -o PDB, --pdb PDB Path to output PDB directory + --num-recycles NUM_RECYCLES + Number of recycles to run. Defaults to number used in + training (4). + --max-tokens-per-batch MAX_TOKENS_PER_BATCH + Maximum number of tokens per gpu forward-pass. This + will group shorter sequences together for batched + prediction. Lowering this can help with out of memory + issues, if these occur on short sequences. + --chunk-size CHUNK_SIZE + Chunks axial attention computation to reduce memory + usage from O(L^2) to O(L). Equivalent to running a for + loop over chunks of of each dimension. Lower values + will result in lower memory usage at the cost of + speed. Recommended values: 128, 64, 32. Default: None. + --cpu-only CPU only + --cpu-offload Enable CPU offloading +``` + +The command will make one prediction for every sequence in the fasta file. Multimers can be predicted and should be entered in the fasta file as a single sequence, with chains seprated by a ":" character. + +By default, predictions will be batched together so that shorter sequences are predicted simultaneously. This can be disabled by setting `--max-tokens-per-batch=0`. Batching can significantly improve prediction speed on shorter sequences. + +The `--cpu-offload` flag can be useful for making predictions on longer sequences. It will attempt to offload some parameters to the CPU RAM, rather than storing on GPU. + +Finally, the ablation experiments for LMs of varying sizes [Lin et al. 2022 table S1](https://www.science.org/doi/abs/10.1126/science.ade2574) are released as `esm.pretrained.esmfold_structure_module_only_*()`. We don't recommend using these models for structure prediction. + + +### Compute embeddings in bulk from FASTA + +We provide a command line interface (`esm-extract`) that efficiently extracts embeddings in bulk for a FASTA file from the ESM: +``` +usage: esm-extract [-h] [--toks_per_batch TOKS_PER_BATCH] + [--repr_layers REPR_LAYERS [REPR_LAYERS ...]] --include + {mean,per_tok,bos,contacts} + [{mean,per_tok,bos,contacts} ...] + [--truncation_seq_length TRUNCATION_SEQ_LENGTH] + model_location fasta_file output_dir + +Extract per-token representations and model outputs for sequences in a FASTA +file + +positional arguments: + model_location PyTorch model file OR name of pretrained model to + download (see README for models) + fasta_file FASTA file on which to extract representations + output_dir output directory for extracted representations + +optional arguments: + -h, --help show this help message and exit + --toks_per_batch TOKS_PER_BATCH + maximum batch size + --repr_layers REPR_LAYERS [REPR_LAYERS ...] + layers indices from which to extract representations + (0 to num_layers, inclusive) + --include {mean,per_tok,bos,contacts} [{mean,per_tok,bos,contacts} ...] + specify which representations to return + --truncation_seq_length TRUNCATION_SEQ_LENGTH + truncate sequences longer than the given value +``` + +The following commands allow the extraction of the final-layer embedding for a FASTA file from the ESM-2 model: + +```bash +esm-extract esm2_t33_650M_UR50D examples/data/some_proteins.fasta \ + examples/data/some_proteins_emb_esm2 --repr_layers 0 32 33 --include +``` +```bash +python scripts/extract.py esm2_t33_650M_UR50D examples/data/some_proteins.fasta \ + examples/data/some_proteins_emb_esm2 --repr_layers 0 32 33 --include mean per_tok +``` + +A cuda device is optional and will be auto-detected. + +Directory `some_proteins_emb_esm2/` now contains one `.pt` file per FASTA sequence; use `torch.load()` to load them. +`scripts/extract.py` has flags that determine what's included in the `.pt` file: +* `--repr-layers` (default: final only) selects which layers to include embeddings from. +* `--include` specifies what embeddings to save. You can use the following: + * `per_tok` includes the full sequence, with an embedding per amino acid (seq_len x hidden_dim). + * `mean` includes the embeddings averaged over the full sequence, per layer. + * `bos` includes the embeddings from the beginning-of-sequence token. + (NOTE: Don't use with the pre-trained models - we trained without bos-token supervision) + + +### CPU offloading for inference with large models +If you want to load very large models like 15B and/or do inference on long sequences on your machine, regular GPU inference may lead to OOM errors. +We show how to load the model with Fairscale's [Fully Sharded Data Parallel (FSDP)](https://fairscale.readthedocs.io/en/stable/api/nn/fsdp.html) and +use its CPU offloading feature. +This allows to do inference of large models on a single GPU. +Please check out `examples/esm2_infer_fairscale_fsdp_cpu_offloading.py` for more details. + +### Zero-shot variant prediction +See "[examples/variant-prediction/](examples/variant-prediction/)" for code and pre-trained weights for the ESM-1v models described in +[Language models enable zero-shot prediction of the effects of mutations on protein function. (Meier et al. 2021)](https://doi.org/10.1101/2021.07.09.450648). + +Note that ESM-2 could be used for variant prediction as well, and is expected to have similar performance to ESM-1v. + +### Inverse folding +See "[examples/inverse_folding/](examples/inverse_folding/)" for detailed user guide. The ESM-IF1 model is described as `GVPTransformer` in [Learning inverse folding from millions of predicted structures. (Hsu et al. 2022)](https://doi.org/10.1101/2022.04.10.487779). + +We also provide a colab notebook for the sequence design and sequence scoring functionalities. + +[](https://colab.research.google.com/github/facebookresearch/esm/blob/main/examples/inverse_folding/notebook_multichain.ipynb) + +The ESM-IF1 inverse folding model is built for predicting protein sequences +from their backbone atom coordinates. We provide scripts here 1) to sample sequence +designs for a given structure and 2) to score sequences for a given structure. + +Trained with 12M protein structures predicted by AlphaFold2, the ESM-IF1 +model consists of invariant geometric input processing layers followed by a +sequence-to-sequence transformer, and achieves 51% native sequence recovery on +structurally held-out backbones with 72% recovery for buried residues. +The model is also trained with span masking to tolerate missing backbone +coordinates and therefore can predict sequences for partially masked structures. + +#### Sample sequence designs for a given structure +The environment setup is described in [this subsection of examples/inverse_folding](examples/inverse_folding#recommended-environment). + +To sample sequences for a given structure in PDB or mmCIF format, use the +`sample_sequences.py` script. The input file can have either `.pdb` or +`.cif` as suffix. + +For example, to sample 3 sequence designs for the golgi casein kinase structure +(PDB [5YH2](https://www.rcsb.org/structure/5yh2); [PDB Molecule of the Month +from January 2022](https://pdb101.rcsb.org/motm/265)), we can run the following +command from the esm root directory: +```bash +python examples/inverse_folding/sample_sequences.py examples/inverse_folding/data/5YH2.pdb \ + --chain C --temperature 1 --num-samples 3 --outpath examples/inverse_folding/output/sampled_sequences.fasta +``` + +The sampled sequences will be saved in a fasta format to the specified output file. + +The temperature parameter controls the sharpness of the probability +distribution for sequence sampling. Higher sampling temperatures yield more +diverse sequences but likely with lower native sequence recovery. +The default sampling temperature is 1. To optimize for native sequence +recovery, we recommend sampling with low temperature such as 1e-6. + +#### Scoring sequences +To score the conditional log-likelihoods for sequences conditioned on a given +structure, use the `score_log_likelihoods.py` script. + +For example, to score the sequences in `examples/inverse_folding/data/5YH2_mutated_seqs.fasta` +according to the structure in `examples/inverse_folding/data/5YH2.pdb`, we can run +the following command from the esm root directory: +``` +python examples/inverse_folding/score_log_likelihoods.py examples/inverse_folding/data/5YH2.pdb \ + examples/inverse_folding/data/5YH2_mutated_seqs.fasta --chain C \ + --outpath examples/inverse_folding/output/5YH2_mutated_seqs_scores.csv +``` + +The conditional log-likelihoods are saved in a csv format in the specified output path. +The output values are the average log-likelihoods averaged over all amino acids in a sequence. + +For more information, see "[./examples/inverse_folding/](examples/inverse_folding/)" for detailed user guide. + +## ESM Metagenomic Atlas + +Please visit the [ESM Metagenomic Atlas](https://esmatlas.com/) website, and +see our [blog post](https://ai.facebook.com/blog/protein-folding-esmfold-metagenomics/) to learn more. + +Bulk download instructions available at a seperate README [here](scripts/atlas/README.md). + +The Atlas resources include a page to [fold a sequence using ESMFold](https://esmatlas.com/resources?action=fold), +searching a subset of the ESM Atlas by [structure](https://esmatlas.com/resources?action=search_structure) or +[sequence](https://esmatlas.com/resources?action=search_sequence), +as well as an [API](https://esmatlas.com/about#api) to access those resources programmatically. + +Foldseek provides search against the Atlas without the length limitation [here](https://search.foldseek.com/search). + + +## Notebooks + +### Inverse folding - predicting or scoring sequences based on backbone structures + +[](https://colab.research.google.com/github/facebookresearch/esm/blob/main/examples/inverse_folding/notebook.ipynb) + +The ESM-IF1 inverse folding model predicts protein sequences from their backbone atom coordinates, trained with 12M protein structures predicted by AlphaFold2. +This notetook guide you through examples of sampling sequences, calculating conditional log-likelihoods, and extracting encoder output as structure representation. + +### Supervised variant prediction - training a classifier on the embeddings + +[](https://colab.research.google.com/github/facebookresearch/esm/blob/main/examples/sup_variant_prediction.ipynb) + + +To help you get started with using the embeddings, this [jupyter notebook tutorial](examples/sup_variant_prediction.ipynb) shows how to train a supervised variant predictor using embeddings from ESM-1. +You can adopt a similar protocol to train a model for any downstream task, even with limited data. +First you can obtain the embeddings for ``examples/data/P62593.fasta`` either by [downloading the precomputed](https://dl.fbaipublicfiles.com/fair-esm/examples/P62593_reprs.tar.gz) embeddings +as instructed in the notebook or by running the following: + +```bash +# Obtain the embeddings +python scripts/extract.py esm1v_t33_650M_UR90S_1 examples/data/P62593.fasta \ + examples/data/P62593_emb_esm1v --repr_layers 33 --include mean +``` + +Then, follow the remaining instructions in the tutorial. You can also run the tutorial in a [colab notebook](https://colab.research.google.com/github/facebookresearch/esm/blob/main/examples/sup_variant_prediction.ipynb). + +**Note, alternatively use [the newer instructions for zero-shot variant prediction](examples/variant-prediction/), +which predicts mutational effects without any supervised training.** + + +### Unsupervised contact prediction +[](https://colab.research.google.com/github/facebookresearch/esm/blob/main/examples/contact_prediction.ipynb) + +This [jupyter notebook tutorial](examples/contact_prediction.ipynb) demonstrates contact prediction with both the ESM-2 and MSA Transformer (ESM-MSA-1) models. +Contact prediction is based on a logistic regression over the model's attention maps. +This methodology is based on our ICLR 2021 paper, +[Transformer protein language models are unsupervised structure learners. (Rao et al. 2020)](https://doi.org/10.1101/2020.12.15.422761) +The MSA Transformer (ESM-MSA-1) takes a multiple sequence alignment (MSA) as input, and uses the tied row self-attention maps in the same way. +See [MSA Transformer. (Rao et al. 2021)](https://www.biorxiv.org/content/10.1101/2021.02.12.430858v1). + +To get unsupervised attention-based contacts, call `model.predict_contacts(tokens)` or `model(tokens, return_contacts=True)`. + + +### ESMStructuralSplitDataset and self-attention contact prediction +[](https://colab.research.google.com/github/facebookresearch/esm/blob/main/examples/esm_structural_dataset.ipynb) + +And this [jupyter notebook tutorial](examples/esm_structural_dataset.ipynb) shows how to load and index the `ESMStructuralSplitDataset`, +and computes the self-attention map unsupervised contact predictions using ESM-2. + + +## Available Models and Datasets + +### Pre-trained Models + +| Shorthand | `esm.pretrained.` | #layers | #params | Dataset | Embedding Dim | Model URL (automatically downloaded to `~/.cache/torch/hub/checkpoints`) | +|-----------|---------------------|---------|-------------|---------|---------------|-----------------------------------------------------------------------| +| ESM-2 | `esm2_t48_15B_UR50D` | 48 | 15B | UR50/D 2021_04 | 5120 | https://dl.fbaipublicfiles.com/fair-esm/models/esm2_t48_15B_UR50D.pt | +| | `esm2_t36_3B_UR50D` | 36 | 3B | UR50/D 2021_04 | 2560 | https://dl.fbaipublicfiles.com/fair-esm/models/esm2_t36_3B_UR50D.pt | +| | `esm2_t33_650M_UR50D` | 33 | 650M | UR50/D 2021_04 | 1280 | https://dl.fbaipublicfiles.com/fair-esm/models/esm2_t33_650M_UR50D.pt | +| | `esm2_t30_150M_UR50D` | 30 | 150M | UR50/D 2021_04 | 640 | https://dl.fbaipublicfiles.com/fair-esm/models/esm2_t30_150M_UR50D.pt | +| | `esm2_t12_35M_UR50D` | 12 | 35M | UR50/D 2021_04 | 480 | https://dl.fbaipublicfiles.com/fair-esm/models/esm2_t12_35M_UR50D.pt | +| | `esm2_t6_8M_UR50D` | 6 | 8M | UR50/D 2021_04 | 320 | https://dl.fbaipublicfiles.com/fair-esm/models/esm2_t6_8M_UR50D.pt | +| ESMFold | `esmfold_v1` | 48 (+36) | 690M (+3B) | UR50/D 2021_04 | - | https://dl.fbaipublicfiles.com/fair-esm/models/esmfold_3B_v1.pt | +| | `esmfold_v0` | 48 (+36) | 690M (+3B) | UR50/D 2021_04 | - | https://dl.fbaipublicfiles.com/fair-esm/models/esmfold_3B_v0.pt | +| | `esmfold_structure_module_only_*` | 0 (+various) | various | UR50/D 2021_04 | - | https://dl.fbaipublicfiles.com/fair-esm/models/esmfold_structure_module_only_* | +| ESM-IF1 | `esm_if1_gvp4_t16_142M_UR50` | 20 | 124M | CATH 4.3 + predicted structures for UR50 | 512 | https://dl.fbaipublicfiles.com/fair-esm/models/esm_if1_gvp4_t16_142M_UR50.pt | +| ESM-1v | `esm1v_t33_650M_UR90S_[1-5]` | 33 | 650M | UR90/S 2020_03 | 1280 | https://dl.fbaipublicfiles.com/fair-esm/models/esm1v_t33_650M_UR90S_1.pt | +| ESM-MSA-1b| `esm_msa1b_t12_100M_UR50S` | 12 | 100M | UR50/S + MSA 2018_03 | 768 | https://dl.fbaipublicfiles.com/fair-esm/models/esm_msa1b_t12_100M_UR50S.pt | +| ESM-MSA-1 | `esm_msa1_t12_100M_UR50S` | 12 | 100M | UR50/S + MSA 2018_03 | 768 | https://dl.fbaipublicfiles.com/fair-esm/models/esm_msa1_t12_100M_UR50S.pt | +| ESM-1b | `esm1b_t33_650M_UR50S` | 33 | 650M | UR50/S 2018_03 | 1280 | https://dl.fbaipublicfiles.com/fair-esm/models/esm1b_t33_650M_UR50S.pt | +| ESM-1 | `esm1_t34_670M_UR50S` | 34 | 670M | UR50/S 2018_03 | 1280 | https://dl.fbaipublicfiles.com/fair-esm/models/esm1_t34_670M_UR50S.pt | +| | `esm1_t34_670M_UR50D` | 34 | 670M | UR50/D 2018_03 | 1280 | https://dl.fbaipublicfiles.com/fair-esm/models/esm1_t34_670M_UR50D.pt | +| | `esm1_t34_670M_UR100` | 34 | 670M | UR100 2018_03 | 1280 | https://dl.fbaipublicfiles.com/fair-esm/models/esm1_t34_670M_UR100.pt | +| | `esm1_t12_85M_UR50S` | 12 | 85M | UR50/S 2018_03 | 768 | https://dl.fbaipublicfiles.com/fair-esm/models/esm1_t12_85M_UR50S.pt | +| | `esm1_t6_43M_UR50S` | 6 | 43M | UR50/S 2018_03 | 768 | https://dl.fbaipublicfiles.com/fair-esm/models/esm1_t6_43M_UR50S.pt | + + +Here is a chronological list of the released models and the paper they were introduced in: + +| Shorthand | Release Notes | +|------------|---------------| +| ESM-1 | Released with Rives et al. 2019 (Aug 2020 update). | +| ESM-1b | Released with Rives et al. 2019 (Dec 2020 update). See Appendix B. | +| ESM-MSA-1 | Released with Rao et al. 2021 (Preprint v1). | +| ESM-MSA-1b | Released with Rao et al. 2021 (ICML'21 version, June 2021). | +| ESM-1v | Released with Meier et al. 2021. | +| ESM-IF1 | Released with Hsu et al. 2022. | +| ESM-2 | Released with Lin et al. 2022. | + +### ESM Structural Split Dataset +This is a five-fold cross validation dataset of protein domain structures that can be used to measure generalization of representations +across different levels of structural dissimilarity. +The dataset implements structural holdouts at the family, superfamily, and fold +level. The SCOPe database is used to classify domains. Independently for each level of structural hold-out, +the domains are split into 5 equal sets, i.e. five sets of folds, superfamilies, or families. This ensures +that for each of the five partitions, structures having the same classification do not appear in both the +train and test sets. For a given classification level each structure appears in a test set once, so that +in the cross validation experiment each of the structures will be evaluated exactly once. + +The dataset provides 3d coordinates, distance maps, and secondary structure labels. +For further details on the construction of the dataset +see [Rives et al. 2019](https://doi.org/10.1101/622803) Appendix A.10. + +This [jupyter notebook tutorial](examples/esm_structural_dataset.ipynb) shows how to load and index the `ESMStructuralSplitDataset`. + +`ESMStructuralSplitDataset`, upon initializing, will download `splits` and `pkl`. +We also provide `msas` for each of the domains. The data can be directly downloaded below. + +| Name | Description | URL | +|--------|-------------------------------------------------------------------------------|-----------------------------------------------------------------------| +| splits | train/valid splits | https://dl.fbaipublicfiles.com/fair-esm/structural-data/splits.tar.gz | +| pkl | pkl objects containing sequence, SSP labels, distance map, and 3d coordinates | https://dl.fbaipublicfiles.com/fair-esm/structural-data/pkl.tar.gz | +| msas | a3m files containing MSA for each domain | https://dl.fbaipublicfiles.com/fair-esm/structural-data/msas.tar.gz | + +### Pre-training Dataset Split +The split files establishing which UniRef50 clusters were used as held-out evaluation set for pre-training +in [Rives et al. 2019](https://doi.org/10.1101/622803) and [Rao et al. 2021](https://doi.org/10.1101/2021.02.12.430858) can be found here: +* [UniRef50 IDs of evaluation set](https://dl.fbaipublicfiles.com/fair-esm/pretraining-data/uniref201803_ur50_valid_headers.txt.gz): 3.016 M clusters +* [UniRef100 IDs of evaluation set](https://dl.fbaipublicfiles.com/fair-esm/pretraining-data/uniref201803_ur100_valid_headers.txt.gz): 13.745 M proteins, expanding the same UniRef50 clusters. + +These files only contain only the UniRef50 IDs and UniRef100 IDs corresponding to the [UniRef database, 2018-03 release](https://ftp.uniprot.org/pub/databases/uniprot/previous_releases/release-2018_03/uniref/) +which is released by the UniProt Consortium under a [Creative Commons Attribution (CC BY 4.0) License](https://www.uniprot.org/help/license). + + +### Comparison to related works + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
TaskUnsupervised contact predictionStructure Prediction
Test setLarge validCASP14CAMEO (Apr-Jun 2022)CASP14CAMEO (Apr-Jun 2022)
Gremlin (Potts)39.3
TAPE11.2
ProtBert-BFD34.1
Prot-T5-XL-BFD35.646.162.6
Prot-T5-XL-Ur50 (3B)47.949.869.4
ESM-133.7
ESM-1b41.124.43941.664.5
ESM-1v35.3
ESM-MSA-1b57.4
ESM-2 (8M)15.99.815.736.748.1
ESM-2 (35M)28.816.428.441.456.4
ESM-2 (150M)42.226.840.149.064.9
ESM-2 (700M)50.132.547.651.370.1
ESM-2 (3B)52.734.049.952.571.8
ESM-2 (15B)54.537.051.755.472.1
+ +Comparison to related protein language models on structure prediction tasks. + +* All contact numbers are the top-L,LR precision metric, where long range means sequence separation of at least 24 residues +* For unsupervised contact prediction, a sparse linear combination of the attention heads is used to directly predict protein contacts, +fitted with logistic regression on 20 structures. +For more details on the method, see [Rao et al. 2020](https://doi.org/10.1101/2020.12.15.422761). +* For structure prediction, an AlphaFold2 structure module is trained directly from the frozen language model embeddings. +For more details on the method, see [Lin et al. 2022](https://www.science.org/doi/abs/10.1126/science.ade2574). +* Direct coupling analysis methods (Gremlin, mfDCA, Psicov) and ESM-MSA-1 use the [trRosetta MSAs](https://yanglab.nankai.edu.cn/trRosetta/benchmark/), while other methods predict from single sequence. + + +## Citations + +If you find the models useful in your research, we ask that you cite the relevant paper: + +```bibtex +@article{rives2019biological, + author={Rives, Alexander and Meier, Joshua and Sercu, Tom and Goyal, Siddharth and Lin, Zeming and Liu, Jason and Guo, Demi and Ott, Myle and Zitnick, C. Lawrence and Ma, Jerry and Fergus, Rob}, + title={Biological Structure and Function Emerge from Scaling Unsupervised Learning to 250 Million Protein Sequences}, + year={2019}, + doi={10.1101/622803}, + url={https://www.biorxiv.org/content/10.1101/622803v4}, + journal={PNAS} +} +``` + +For the self-attention contact prediction: + +```bibtex +@article{rao2020transformer, + author = {Rao, Roshan M and Meier, Joshua and Sercu, Tom and Ovchinnikov, Sergey and Rives, Alexander}, + title={Transformer protein language models are unsupervised structure learners}, + year={2020}, + doi={10.1101/2020.12.15.422761}, + url={https://www.biorxiv.org/content/10.1101/2020.12.15.422761v1}, + journal={bioRxiv} +} +``` + +For the MSA Transformer: + +```bibtex +@article{rao2021msa, + author = {Rao, Roshan and Liu, Jason and Verkuil, Robert and Meier, Joshua and Canny, John F. and Abbeel, Pieter and Sercu, Tom and Rives, Alexander}, + title={MSA Transformer}, + year={2021}, + doi={10.1101/2021.02.12.430858}, + url={https://www.biorxiv.org/content/10.1101/2021.02.12.430858v1}, + journal={bioRxiv} +} +``` + +For variant prediction using ESM-1v: + +```bibtex +@article{meier2021language, + author = {Meier, Joshua and Rao, Roshan and Verkuil, Robert and Liu, Jason and Sercu, Tom and Rives, Alexander}, + title = {Language models enable zero-shot prediction of the effects of mutations on protein function}, + year={2021}, + doi={10.1101/2021.07.09.450648}, + url={https://www.biorxiv.org/content/10.1101/2021.07.09.450648v1}, + journal={bioRxiv} +} +``` + +For inverse folding using ESM-IF1: + +```bibtex +@article{hsu2022learning, + author = {Hsu, Chloe and Verkuil, Robert and Liu, Jason and Lin, Zeming and Hie, Brian and Sercu, Tom and Lerer, Adam and Rives, Alexander}, + title = {Learning inverse folding from millions of predicted structures}, + year = {2022}, + doi = {10.1101/2022.04.10.487779}, + url = {https://www.biorxiv.org/content/early/2022/04/10/2022.04.10.487779}, + journal = {ICML} +} +``` + +For the ESM-2 language model and ESMFold: + +```bibtex +@article{lin2022language, + title={Language models of protein sequences at the scale of evolution enable accurate structure prediction}, + author={Lin, Zeming and Akin, Halil and Rao, Roshan and Hie, Brian and Zhu, Zhongkai and Lu, Wenting and Smetanin, Nikita and dos Santos Costa, Allan and Fazel-Zarandi, Maryam and Sercu, Tom and Candido, Sal and others}, + journal={bioRxiv}, + year={2022}, + publisher={Cold Spring Harbor Laboratory} +} +``` + +Much of this code builds on the [fairseq](https://github.com/pytorch/fairseq) sequence modeling framework. We use fairseq internally for our protein language modeling research. We highly recommend trying it out if you'd like to pre-train protein language models from scratch. + +Additionally, if you would like to use the variant prediction benchmark from Meier et al. (2021), we provide a bibtex file with citations for all data in [./examples/variant-prediction/mutation_data.bib](./examples/variant-prediction/mutation_data.bib). You can cite each paper individually, or add all citations in bulk using the LaTeX command: + +```tex +\nocite{wrenbeck2017deep,klesmith2015comprehensive,haddox2018mapping,romero2015dissecting,firnberg2014comprehensive,deng2012deep,stiffler2015evolvability,jacquier2013capturing,findlay2018comprehensive,mclaughlin2012spatial,kitzman2015massively,doud2016accurate,pokusaeva2019experimental,mishra2016systematic,kelsic2016rna,melnikov2014comprehensive,brenan2016phenotypic,rockah2015systematic,wu2015functional,aakre2015evolving,qi2014quantitative,matreyek2018multiplex,bandaru2017deconstruction,roscoe2013analyses,roscoe2014systematic,mavor2016determination,chan2017correlation,melamed2013deep,starita2013activity,araya2012fundamental} +``` + +## License + +This source code is licensed under the MIT license found in the `LICENSE` file +in the root directory of this source tree. + +ESM Metagenomic Atlas (also referred to as “ESM Metagenomic Structure Atlas” or “ESM Atlas”) data is available under a CC BY 4.0 license for academic and commercial use. Copyright (c) Meta Platforms, Inc. All Rights Reserved. Use of the ESM Metagenomic Atlas data is subject to the Meta Open Source [Terms of Use](https://opensource.fb.com/legal/terms/) and [Privacy Policy](https://opensource.fb.com/legal/privacy/). diff --git a/esm/source/__init__.py b/esm/source/__init__.py new file mode 100644 index 0000000000000000000000000000000000000000..6e7e6bcbc775cbefa4e7b7f1605470cf38a6f781 --- /dev/null +++ b/esm/source/__init__.py @@ -0,0 +1,4 @@ +# -*- coding: utf-8 -*- +""" +esm 项目包初始化文件 +""" diff --git a/esm/source/environment.yml b/esm/source/environment.yml new file mode 100644 index 0000000000000000000000000000000000000000..2d1b70d1a86513175e05f614b98999157dcea13b --- /dev/null +++ b/esm/source/environment.yml @@ -0,0 +1,36 @@ +name: esmfold +channels: + - conda-forge + - bioconda + - pytorch +dependencies: + - conda-forge::python=3.7 + - conda-forge::setuptools=59.5.0 + - conda-forge::pip + - conda-forge::openmm=7.5.1 + - conda-forge::pdbfixer + - conda-forge::cudatoolkit==11.3.* + - conda-forge::einops + - conda-forge::fairscale + - conda-forge::omegaconf + - conda-forge::hydra-core + - conda-forge::pandas + - conda-forge::pytest + - bioconda::hmmer==3.3.2 + - bioconda::hhsuite==3.3.0 + - bioconda::kalign2==2.04 + - pytorch::pytorch=1.12.* + - pip: + - biopython==1.79 + - deepspeed==0.5.9 + - dm-tree==0.1.6 + - ml-collections==0.1.0 + - numpy==1.21.2 + - PyYAML==5.4.1 + - requests==2.26.0 + - scipy==1.7.1 + - tqdm==4.62.2 + - typing-extensions==3.10.0.2 + - pytorch_lightning==1.5.10 + - wandb==0.12.21 + - git+https://github.com/NVIDIA/dllogger.git diff --git a/esm/source/esm/__init__.py b/esm/source/esm/__init__.py new file mode 100644 index 0000000000000000000000000000000000000000..907081d4111c66358b51322add5b261bffcdf5b8 --- /dev/null +++ b/esm/source/esm/__init__.py @@ -0,0 +1,12 @@ +# Copyright (c) Facebook, Inc. and its affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from .version import version as __version__ # noqa + +from .data import Alphabet, BatchConverter, FastaBatchedDataset # noqa +from .model.esm1 import ProteinBertModel # noqa +from .model.esm2 import ESM2 # noqa +from .model.msa_transformer import MSATransformer #noqa +from . import pretrained # noqa diff --git a/esm/source/esm/axial_attention.py b/esm/source/esm/axial_attention.py new file mode 100644 index 0000000000000000000000000000000000000000..78b02eb3db6ea996ce65018acf4af9b1e47b0b89 --- /dev/null +++ b/esm/source/esm/axial_attention.py @@ -0,0 +1,239 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import math +import torch +import torch.nn as nn + + +class RowSelfAttention(nn.Module): + """Compute self-attention over rows of a 2D input.""" + + def __init__( + self, + embed_dim, + num_heads, + dropout=0.0, + max_tokens_per_msa: int = 2 ** 16, + ): + super().__init__() + self.num_heads = num_heads + self.dropout = dropout + self.head_dim = embed_dim // num_heads + self.scaling = self.head_dim ** -0.5 + self.max_tokens_per_msa = max_tokens_per_msa + self.attn_shape = "hnij" + + self.k_proj = nn.Linear(embed_dim, embed_dim) + self.v_proj = nn.Linear(embed_dim, embed_dim) + self.q_proj = nn.Linear(embed_dim, embed_dim) + + self.out_proj = nn.Linear(embed_dim, embed_dim) + self.dropout_module = nn.Dropout(dropout) + + def align_scaling(self, q): + num_rows = q.size(0) + return self.scaling / math.sqrt(num_rows) + + def _batched_forward( + self, + x, + self_attn_mask=None, + self_attn_padding_mask=None, + ): + num_rows, num_cols, batch_size, embed_dim = x.size() + max_rows = max(1, self.max_tokens_per_msa // num_cols) + attns = 0 + scaling = self.align_scaling(x) + for start in range(0, num_rows, max_rows): + attn_weights = self.compute_attention_weights( + x[start : start + max_rows], + scaling, + self_attn_mask=self_attn_mask, + self_attn_padding_mask=self_attn_padding_mask[:, start : start + max_rows] + if self_attn_padding_mask is not None + else None, + ) + attns += attn_weights + attn_probs = attns.softmax(-1) + attn_probs = self.dropout_module(attn_probs) + + outputs = [] + for start in range(0, num_rows, max_rows): + output = self.compute_attention_update(x[start : start + max_rows], attn_probs) + outputs.append(output) + + output = torch.cat(outputs, 0) + return output, attn_probs + + def compute_attention_weights( + self, + x, + scaling: float, + self_attn_mask=None, + self_attn_padding_mask=None, + ): + num_rows, num_cols, batch_size, embed_dim = x.size() + q = self.q_proj(x).view(num_rows, num_cols, batch_size, self.num_heads, self.head_dim) + k = self.k_proj(x).view(num_rows, num_cols, batch_size, self.num_heads, self.head_dim) + q *= scaling + if self_attn_padding_mask is not None: + # Zero out any padded aligned positions - this is important since + # we take a sum across the alignment axis. + q *= 1 - self_attn_padding_mask.permute(1, 2, 0).unsqueeze(3).unsqueeze(4).to(q) + + attn_weights = torch.einsum(f"rinhd,rjnhd->{self.attn_shape}", q, k) + + if self_attn_mask is not None: + raise NotImplementedError + # Mask Size: [B x R x C], Weights Size: [H x B x C x C] + + if self_attn_padding_mask is not None: + attn_weights = attn_weights.masked_fill( + self_attn_padding_mask[:, 0].unsqueeze(0).unsqueeze(2), + -10000, + ) + + return attn_weights + + def compute_attention_update( + self, + x, + attn_probs, + ): + num_rows, num_cols, batch_size, embed_dim = x.size() + v = self.v_proj(x).view(num_rows, num_cols, batch_size, self.num_heads, self.head_dim) + context = torch.einsum(f"{self.attn_shape},rjnhd->rinhd", attn_probs, v) + context = context.contiguous().view(num_rows, num_cols, batch_size, embed_dim) + output = self.out_proj(context) + return output + + def forward( + self, + x, + self_attn_mask=None, + self_attn_padding_mask=None, + ): + num_rows, num_cols, batch_size, embed_dim = x.size() + if (num_rows * num_cols > self.max_tokens_per_msa) and not torch.is_grad_enabled(): + return self._batched_forward(x, self_attn_mask, self_attn_padding_mask) + else: + scaling = self.align_scaling(x) + attn_weights = self.compute_attention_weights( + x, scaling, self_attn_mask, self_attn_padding_mask + ) + attn_probs = attn_weights.softmax(-1) + attn_probs = self.dropout_module(attn_probs) + output = self.compute_attention_update(x, attn_probs) + return output, attn_probs + + +class ColumnSelfAttention(nn.Module): + """Compute self-attention over columns of a 2D input.""" + + def __init__( + self, + embed_dim, + num_heads, + dropout=0.0, + max_tokens_per_msa: int = 2 ** 16, + ): + super().__init__() + + self.num_heads = num_heads + self.dropout = dropout + self.head_dim = embed_dim // num_heads + self.scaling = self.head_dim ** -0.5 + self.max_tokens_per_msa = max_tokens_per_msa + + self.k_proj = nn.Linear(embed_dim, embed_dim) + self.v_proj = nn.Linear(embed_dim, embed_dim) + self.q_proj = nn.Linear(embed_dim, embed_dim) + + self.out_proj = nn.Linear(embed_dim, embed_dim) + self.dropout_module = nn.Dropout(dropout) + + def _batched_forward( + self, + x, + self_attn_mask=None, + self_attn_padding_mask=None, + ): + num_rows, num_cols, batch_size, embed_dim = x.size() + max_cols = max(1, self.max_tokens_per_msa // num_rows) + outputs = [] + attns = [] + for start in range(0, num_cols, max_cols): + output, attn = self( + x[:, start : start + max_cols], + self_attn_mask=self_attn_mask, + self_attn_padding_mask=self_attn_padding_mask[:, :, start : start + max_cols] + if self_attn_padding_mask is not None + else None, + ) + outputs.append(output) + attns.append(attn) + output = torch.cat(outputs, 1) + attns = torch.cat(attns, 1) + return output, attns + + def compute_attention_update( + self, + x, + self_attn_mask=None, + self_attn_padding_mask=None, + ): + num_rows, num_cols, batch_size, embed_dim = x.size() + if num_rows == 1: + # if there is only 1 position, this is equivalent and doesn't break with padding + attn_probs = torch.ones( + self.num_heads, + num_cols, + batch_size, + num_rows, + num_rows, + device=x.device, + dtype=x.dtype, + ) + output = self.out_proj(self.v_proj(x)) + else: + q = self.q_proj(x).view(num_rows, num_cols, batch_size, self.num_heads, self.head_dim) + k = self.k_proj(x).view(num_rows, num_cols, batch_size, self.num_heads, self.head_dim) + v = self.v_proj(x).view(num_rows, num_cols, batch_size, self.num_heads, self.head_dim) + q *= self.scaling + + attn_weights = torch.einsum("icnhd,jcnhd->hcnij", q, k) + + if self_attn_mask is not None: + raise NotImplementedError + if self_attn_padding_mask is not None: + attn_weights = attn_weights.masked_fill( + self_attn_padding_mask.permute(2, 0, 1).unsqueeze(0).unsqueeze(3), + -10000, + ) + + attn_probs = attn_weights.softmax(-1) + attn_probs = self.dropout_module(attn_probs) + context = torch.einsum("hcnij,jcnhd->icnhd", attn_probs, v) + context = context.contiguous().view(num_rows, num_cols, batch_size, embed_dim) + output = self.out_proj(context) + return output, attn_probs + + def forward( + self, + x, + self_attn_mask=None, + self_attn_padding_mask=None, + ): + num_rows, num_cols, batch_size, embed_dim = x.size() + # if False and num_rows * num_cols > 2 ** 14 and not torch.is_grad_enabled(): + if (num_rows * num_cols) > self.max_tokens_per_msa and not torch.is_grad_enabled(): + return self._batched_forward( + x, + self_attn_mask, + self_attn_padding_mask, + ) + else: + return self.compute_attention_update(x, self_attn_mask, self_attn_padding_mask) diff --git a/esm/source/esm/constants.py b/esm/source/esm/constants.py new file mode 100644 index 0000000000000000000000000000000000000000..9e37c262bb8429d7a2787876dce912496658ecad --- /dev/null +++ b/esm/source/esm/constants.py @@ -0,0 +1,10 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +# fmt: off +proteinseq_toks = { + 'toks': ['L', 'A', 'G', 'V', 'S', 'E', 'R', 'T', 'I', 'D', 'P', 'K', 'Q', 'N', 'F', 'Y', 'M', 'H', 'W', 'C', 'X', 'B', 'U', 'Z', 'O', '.', '-'] +} +# fmt: on diff --git a/esm/source/esm/data.py b/esm/source/esm/data.py new file mode 100644 index 0000000000000000000000000000000000000000..9d98b6f082f9bb966fa0c1c8962f9fa2abd8fb5a --- /dev/null +++ b/esm/source/esm/data.py @@ -0,0 +1,493 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import itertools +import os +from typing import Sequence, Tuple, List, Union +import pickle +import re +import shutil +import torch +from pathlib import Path +from esm.constants import proteinseq_toks + +RawMSA = Sequence[Tuple[str, str]] + + +class FastaBatchedDataset(object): + def __init__(self, sequence_labels, sequence_strs): + self.sequence_labels = list(sequence_labels) + self.sequence_strs = list(sequence_strs) + + @classmethod + def from_file(cls, fasta_file): + sequence_labels, sequence_strs = [], [] + cur_seq_label = None + buf = [] + + def _flush_current_seq(): + nonlocal cur_seq_label, buf + if cur_seq_label is None: + return + sequence_labels.append(cur_seq_label) + sequence_strs.append("".join(buf)) + cur_seq_label = None + buf = [] + + with open(fasta_file, "r") as infile: + for line_idx, line in enumerate(infile): + if line.startswith(">"): # label line + _flush_current_seq() + line = line[1:].strip() + if len(line) > 0: + cur_seq_label = line + else: + cur_seq_label = f"seqnum{line_idx:09d}" + else: # sequence line + buf.append(line.strip()) + + _flush_current_seq() + + assert len(set(sequence_labels)) == len( + sequence_labels + ), "Found duplicate sequence labels" + + return cls(sequence_labels, sequence_strs) + + def __len__(self): + return len(self.sequence_labels) + + def __getitem__(self, idx): + return self.sequence_labels[idx], self.sequence_strs[idx] + + def get_batch_indices(self, toks_per_batch, extra_toks_per_seq=0): + sizes = [(len(s), i) for i, s in enumerate(self.sequence_strs)] + sizes.sort() + batches = [] + buf = [] + max_len = 0 + + def _flush_current_buf(): + nonlocal max_len, buf + if len(buf) == 0: + return + batches.append(buf) + buf = [] + max_len = 0 + + for sz, i in sizes: + sz += extra_toks_per_seq + if max(sz, max_len) * (len(buf) + 1) > toks_per_batch: + _flush_current_buf() + max_len = max(max_len, sz) + buf.append(i) + + _flush_current_buf() + return batches + + +class Alphabet(object): + def __init__( + self, + standard_toks: Sequence[str], + prepend_toks: Sequence[str] = ("", "", "", ""), + append_toks: Sequence[str] = ("", "", ""), + prepend_bos: bool = True, + append_eos: bool = False, + use_msa: bool = False, + ): + self.standard_toks = list(standard_toks) + self.prepend_toks = list(prepend_toks) + self.append_toks = list(append_toks) + self.prepend_bos = prepend_bos + self.append_eos = append_eos + self.use_msa = use_msa + + self.all_toks = list(self.prepend_toks) + self.all_toks.extend(self.standard_toks) + for i in range((8 - (len(self.all_toks) % 8)) % 8): + self.all_toks.append(f"") + self.all_toks.extend(self.append_toks) + + self.tok_to_idx = {tok: i for i, tok in enumerate(self.all_toks)} + + self.unk_idx = self.tok_to_idx[""] + self.padding_idx = self.get_idx("") + self.cls_idx = self.get_idx("") + self.mask_idx = self.get_idx("") + self.eos_idx = self.get_idx("") + self.all_special_tokens = ['', '', '', '', ''] + self.unique_no_split_tokens = self.all_toks + + def __len__(self): + return len(self.all_toks) + + def get_idx(self, tok): + return self.tok_to_idx.get(tok, self.unk_idx) + + def get_tok(self, ind): + return self.all_toks[ind] + + def to_dict(self): + return self.tok_to_idx.copy() + + def get_batch_converter(self, truncation_seq_length: int = None): + if self.use_msa: + return MSABatchConverter(self, truncation_seq_length) + else: + return BatchConverter(self, truncation_seq_length) + + @classmethod + def from_architecture(cls, name: str) -> "Alphabet": + if name in ("ESM-1", "protein_bert_base"): + standard_toks = proteinseq_toks["toks"] + prepend_toks: Tuple[str, ...] = ("", "", "", "") + append_toks: Tuple[str, ...] = ("", "", "") + prepend_bos = True + append_eos = False + use_msa = False + elif name in ("ESM-1b", "roberta_large"): + standard_toks = proteinseq_toks["toks"] + prepend_toks = ("", "", "", "") + append_toks = ("",) + prepend_bos = True + append_eos = True + use_msa = False + elif name in ("MSA Transformer", "msa_transformer"): + standard_toks = proteinseq_toks["toks"] + prepend_toks = ("", "", "", "") + append_toks = ("",) + prepend_bos = True + append_eos = False + use_msa = True + elif "invariant_gvp" in name.lower(): + standard_toks = proteinseq_toks["toks"] + prepend_toks = ("", "", "", "") + append_toks = ("", "", "") + prepend_bos = True + append_eos = False + use_msa = False + else: + raise ValueError("Unknown architecture selected") + return cls(standard_toks, prepend_toks, append_toks, prepend_bos, append_eos, use_msa) + + def _tokenize(self, text) -> str: + return text.split() + + def tokenize(self, text, **kwargs) -> List[str]: + """ + Inspired by https://github.com/huggingface/transformers/blob/master/src/transformers/tokenization_utils.py + Converts a string in a sequence of tokens, using the tokenizer. + + Args: + text (:obj:`str`): + The sequence to be encoded. + + Returns: + :obj:`List[str]`: The list of tokens. + """ + + def split_on_token(tok, text): + result = [] + split_text = text.split(tok) + for i, sub_text in enumerate(split_text): + # AddedToken can control whitespace stripping around them. + # We use them for GPT2 and Roberta to have different behavior depending on the special token + # Cf. https://github.com/huggingface/transformers/pull/2778 + # and https://github.com/huggingface/transformers/issues/3788 + # We strip left and right by default + if i < len(split_text) - 1: + sub_text = sub_text.rstrip() + if i > 0: + sub_text = sub_text.lstrip() + + if i == 0 and not sub_text: + result.append(tok) + elif i == len(split_text) - 1: + if sub_text: + result.append(sub_text) + else: + pass + else: + if sub_text: + result.append(sub_text) + result.append(tok) + return result + + def split_on_tokens(tok_list, text): + if not text.strip(): + return [] + + tokenized_text = [] + text_list = [text] + for tok in tok_list: + tokenized_text = [] + for sub_text in text_list: + if sub_text not in self.unique_no_split_tokens: + tokenized_text.extend(split_on_token(tok, sub_text)) + else: + tokenized_text.append(sub_text) + text_list = tokenized_text + + return list( + itertools.chain.from_iterable( + ( + self._tokenize(token) + if token not in self.unique_no_split_tokens + else [token] + for token in tokenized_text + ) + ) + ) + + no_split_token = self.unique_no_split_tokens + tokenized_text = split_on_tokens(no_split_token, text) + return tokenized_text + + def encode(self, text): + return [self.tok_to_idx[tok] for tok in self.tokenize(text)] + + +class BatchConverter(object): + """Callable to convert an unprocessed (labels + strings) batch to a + processed (labels + tensor) batch. + """ + + def __init__(self, alphabet, truncation_seq_length: int = None): + self.alphabet = alphabet + self.truncation_seq_length = truncation_seq_length + + def __call__(self, raw_batch: Sequence[Tuple[str, str]]): + # RoBERTa uses an eos token, while ESM-1 does not. + batch_size = len(raw_batch) + batch_labels, seq_str_list = zip(*raw_batch) + seq_encoded_list = [self.alphabet.encode(seq_str) for seq_str in seq_str_list] + if self.truncation_seq_length: + seq_encoded_list = [seq_str[:self.truncation_seq_length] for seq_str in seq_encoded_list] + max_len = max(len(seq_encoded) for seq_encoded in seq_encoded_list) + tokens = torch.empty( + ( + batch_size, + max_len + int(self.alphabet.prepend_bos) + int(self.alphabet.append_eos), + ), + dtype=torch.int64, + ) + tokens.fill_(self.alphabet.padding_idx) + labels = [] + strs = [] + + for i, (label, seq_str, seq_encoded) in enumerate( + zip(batch_labels, seq_str_list, seq_encoded_list) + ): + labels.append(label) + strs.append(seq_str) + if self.alphabet.prepend_bos: + tokens[i, 0] = self.alphabet.cls_idx + seq = torch.tensor(seq_encoded, dtype=torch.int64) + tokens[ + i, + int(self.alphabet.prepend_bos) : len(seq_encoded) + + int(self.alphabet.prepend_bos), + ] = seq + if self.alphabet.append_eos: + tokens[i, len(seq_encoded) + int(self.alphabet.prepend_bos)] = self.alphabet.eos_idx + + return labels, strs, tokens + + +class MSABatchConverter(BatchConverter): + def __call__(self, inputs: Union[Sequence[RawMSA], RawMSA]): + if isinstance(inputs[0][0], str): + # Input is a single MSA + raw_batch: Sequence[RawMSA] = [inputs] # type: ignore + else: + raw_batch = inputs # type: ignore + + batch_size = len(raw_batch) + max_alignments = max(len(msa) for msa in raw_batch) + max_seqlen = max(len(msa[0][1]) for msa in raw_batch) + + tokens = torch.empty( + ( + batch_size, + max_alignments, + max_seqlen + int(self.alphabet.prepend_bos) + int(self.alphabet.append_eos), + ), + dtype=torch.int64, + ) + tokens.fill_(self.alphabet.padding_idx) + labels = [] + strs = [] + + for i, msa in enumerate(raw_batch): + msa_seqlens = set(len(seq) for _, seq in msa) + if not len(msa_seqlens) == 1: + raise RuntimeError( + "Received unaligned sequences for input to MSA, all sequence " + "lengths must be equal." + ) + msa_labels, msa_strs, msa_tokens = super().__call__(msa) + labels.append(msa_labels) + strs.append(msa_strs) + tokens[i, : msa_tokens.size(0), : msa_tokens.size(1)] = msa_tokens + + return labels, strs, tokens + + +def read_fasta( + path, + keep_gaps=True, + keep_insertions=True, + to_upper=False, +): + with open(path, "r") as f: + for result in read_alignment_lines( + f, keep_gaps=keep_gaps, keep_insertions=keep_insertions, to_upper=to_upper + ): + yield result + + +def read_alignment_lines( + lines, + keep_gaps=True, + keep_insertions=True, + to_upper=False, +): + seq = desc = None + + def parse(s): + if not keep_gaps: + s = re.sub("-", "", s) + if not keep_insertions: + s = re.sub("[a-z]", "", s) + return s.upper() if to_upper else s + + for line in lines: + # Line may be empty if seq % file_line_width == 0 + if len(line) > 0 and line[0] == ">": + if seq is not None: + yield desc, parse(seq) + desc = line.strip().lstrip(">") + seq = "" + else: + assert isinstance(seq, str) + seq += line.strip() + assert isinstance(seq, str) and isinstance(desc, str) + yield desc, parse(seq) + + +class ESMStructuralSplitDataset(torch.utils.data.Dataset): + """ + Structural Split Dataset as described in section A.10 of the supplement of our paper. + https://doi.org/10.1101/622803 + + We use the full version of SCOPe 2.07, clustered at 90% sequence identity, + generated on January 23, 2020. + + For each SCOPe domain: + - We extract the sequence from the corresponding PDB file + - We extract the 3D coordinates of the Carbon beta atoms, aligning them + to the sequence. We put NaN where Cb atoms are missing. + - From the 3D coordinates, we calculate a pairwise distance map, based + on L2 distance + - We use DSSP to generate secondary structure labels for the corresponding + PDB file. This is also aligned to the sequence. We put - where SSP + labels are missing. + + For each SCOPe classification level of family/superfamily/fold (in order of difficulty), + we have split the data into 5 partitions for cross validation. These are provided + in a downloaded splits folder, in the format: + splits/{split_level}/{cv_partition}/{train|valid}.txt + where train is the partition and valid is the concatentation of the remaining 4. + + For each SCOPe domain, we provide a pkl dump that contains: + - seq : The domain sequence, stored as an L-length string + - ssp : The secondary structure labels, stored as an L-length string + - dist : The distance map, stored as an LxL numpy array + - coords : The 3D coordinates, stored as an Lx3 numpy array + + """ + + base_folder = "structural-data" + file_list = [ + # url tar filename filename MD5 Hash + ( + "https://dl.fbaipublicfiles.com/fair-esm/structural-data/splits.tar.gz", + "splits.tar.gz", + "splits", + "456fe1c7f22c9d3d8dfe9735da52411d", + ), + ( + "https://dl.fbaipublicfiles.com/fair-esm/structural-data/pkl.tar.gz", + "pkl.tar.gz", + "pkl", + "644ea91e56066c750cd50101d390f5db", + ), + ] + + def __init__( + self, + split_level, + cv_partition, + split, + root_path=os.path.expanduser("~/.cache/torch/data/esm"), + download=False, + ): + super().__init__() + assert split in [ + "train", + "valid", + ], "train_valid must be 'train' or 'valid'" + self.root_path = root_path + self.base_path = os.path.join(self.root_path, self.base_folder) + + # check if root path has what you need or else download it + if download: + self.download() + + self.split_file = os.path.join( + self.base_path, "splits", split_level, cv_partition, f"{split}.txt" + ) + self.pkl_dir = os.path.join(self.base_path, "pkl") + self.names = [] + with open(self.split_file) as f: + self.names = f.read().splitlines() + + def __len__(self): + return len(self.names) + + def _check_exists(self) -> bool: + for (_, _, filename, _) in self.file_list: + fpath = os.path.join(self.base_path, filename) + if not os.path.exists(fpath) or not os.path.isdir(fpath): + return False + return True + + def download(self): + + if self._check_exists(): + print("Files already downloaded and verified") + return + + from torchvision.datasets.utils import download_url + + for url, tar_filename, filename, md5_hash in self.file_list: + download_path = os.path.join(self.base_path, tar_filename) + download_url(url=url, root=self.base_path, filename=tar_filename, md5=md5_hash) + shutil.unpack_archive(download_path, self.base_path) + + def __getitem__(self, idx): + """ + Returns a dict with the following entires + - seq : Str (domain sequence) + - ssp : Str (SSP labels) + - dist : np.array (distance map) + - coords : np.array (3D coordinates) + """ + name = self.names[idx] + pkl_fname = os.path.join(self.pkl_dir, name[1:3], f"{name}.pkl") + with open(pkl_fname, "rb") as f: + obj = pickle.load(f) + return obj diff --git a/esm/source/esm/esmfold/v1/__init__.py b/esm/source/esm/esmfold/v1/__init__.py new file mode 100644 index 0000000000000000000000000000000000000000..e69de29bb2d1d6434b8b29ae775ad8c2e48c5391 diff --git a/esm/source/esm/esmfold/v1/categorical_mixture.py b/esm/source/esm/esmfold/v1/categorical_mixture.py new file mode 100644 index 0000000000000000000000000000000000000000..aedff861c8568d9b6389ab2ab57aa50040543f25 --- /dev/null +++ b/esm/source/esm/esmfold/v1/categorical_mixture.py @@ -0,0 +1,43 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. +import torch + + +class CategoricalMixture: + def __init__(self, param, bins=50, start=0, end=1): + # All tensors are of shape ..., bins. + self.logits = param + bins = torch.linspace( + start, end, bins + 1, device=self.logits.device, dtype=self.logits.dtype + ) + self.v_bins = (bins[:-1] + bins[1:]) / 2 + + def log_prob(self, true): + # Shapes are: + # self.probs: ... x bins + # true : ... + true_index = ( + ( + true.unsqueeze(-1) + - self.v_bins[ + [ + None, + ] + * true.ndim + ] + ) + .abs() + .argmin(-1) + ) + nll = self.logits.log_softmax(-1) + return torch.take_along_dim(nll, true_index.unsqueeze(-1), dim=-1).squeeze(-1) + + def mean(self): + return (self.logits.softmax(-1) @ self.v_bins.unsqueeze(1)).squeeze(-1) + + +def categorical_lddt(logits, bins=50): + # Logits are ..., 37, bins. + return CategoricalMixture(logits, bins=bins).mean() diff --git a/esm/source/esm/esmfold/v1/esmfold.py b/esm/source/esm/esmfold/v1/esmfold.py new file mode 100644 index 0000000000000000000000000000000000000000..ff66db63b5bd105ffa90d73b1ff24f23e1507c04 --- /dev/null +++ b/esm/source/esm/esmfold/v1/esmfold.py @@ -0,0 +1,364 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. +import typing as T +from dataclasses import dataclass +from functools import partial + +import torch +import torch.nn as nn +from torch import nn +from torch.nn import LayerNorm + +import esm +from esm import Alphabet +from esm.esmfold.v1.categorical_mixture import categorical_lddt +from esm.esmfold.v1.misc import ( + batch_encode_sequences, + collate_dense_tensors, + output_to_pdb, +) +from esm.esmfold.v1.trunk import FoldingTrunk, FoldingTrunkConfig +from openfold.data.data_transforms import make_atom14_masks +from openfold.np import residue_constants +from openfold.utils.loss import compute_predicted_aligned_error, compute_tm + + +@dataclass +class ESMFoldConfig: + trunk: T.Any = FoldingTrunkConfig() + lddt_head_hid_dim: int = 128 + + +load_fn = esm.pretrained.load_model_and_alphabet +esm_registry = { + "esm2_8M": partial(load_fn, "esm2_t6_8M_UR50D_500K"), + "esm2_8M_270K": esm.pretrained.esm2_t6_8M_UR50D, + "esm2_35M": partial(load_fn, "esm2_t12_35M_UR50D_500K"), + "esm2_35M_270K": esm.pretrained.esm2_t12_35M_UR50D, + "esm2_150M": partial(load_fn, "esm2_t30_150M_UR50D_500K"), + "esm2_150M_270K": partial(load_fn, "esm2_t30_150M_UR50D_270K"), + "esm2_650M": esm.pretrained.esm2_t33_650M_UR50D, + "esm2_650M_270K": partial(load_fn, "esm2_t33_650M_270K_UR50D"), + "esm2_3B": esm.pretrained.esm2_t36_3B_UR50D, + "esm2_3B_270K": partial(load_fn, "esm2_t36_3B_UR50D_500K"), + "esm2_15B": esm.pretrained.esm2_t48_15B_UR50D, +} + + +class ESMFold(nn.Module): + def __init__(self, esmfold_config=None, **kwargs): + super().__init__() + + self.cfg = esmfold_config if esmfold_config else ESMFoldConfig(**kwargs) + cfg = self.cfg + + self.distogram_bins = 64 + + self.esm, self.esm_dict = esm_registry.get(cfg.esm_type)() + + self.esm.requires_grad_(False) + self.esm.half() + + self.esm_feats = self.esm.embed_dim + self.esm_attns = self.esm.num_layers * self.esm.attention_heads + self.register_buffer("af2_to_esm", ESMFold._af2_to_esm(self.esm_dict)) + self.esm_s_combine = nn.Parameter(torch.zeros(self.esm.num_layers + 1)) + + c_s = cfg.trunk.sequence_state_dim + c_z = cfg.trunk.pairwise_state_dim + + self.esm_s_mlp = nn.Sequential( + LayerNorm(self.esm_feats), + nn.Linear(self.esm_feats, c_s), + nn.ReLU(), + nn.Linear(c_s, c_s), + ) + if cfg.use_esm_attn_map: + self.esm_z_mlp = nn.Sequential( + LayerNorm(self.esm_attns), + nn.Linear(self.esm_attns, c_z), + nn.ReLU(), + nn.Linear(c_z, c_z), + ) + + # 0 is padding, N is unknown residues, N + 1 is mask. + self.n_tokens_embed = residue_constants.restype_num + 3 + self.pad_idx = 0 + self.unk_idx = self.n_tokens_embed - 2 + self.mask_idx = self.n_tokens_embed - 1 + self.embedding = nn.Embedding(self.n_tokens_embed, c_s, padding_idx=0) + + self.trunk = FoldingTrunk(**cfg.trunk) + + self.distogram_head = nn.Linear(c_z, self.distogram_bins) + self.ptm_head = nn.Linear(c_z, self.distogram_bins) + self.lm_head = nn.Linear(c_s, self.n_tokens_embed) + self.lddt_bins = 50 + self.lddt_head = nn.Sequential( + nn.LayerNorm(cfg.trunk.structure_module.c_s), + nn.Linear(cfg.trunk.structure_module.c_s, cfg.lddt_head_hid_dim), + nn.Linear(cfg.lddt_head_hid_dim, cfg.lddt_head_hid_dim), + nn.Linear(cfg.lddt_head_hid_dim, 37 * self.lddt_bins), + ) + + @staticmethod + def _af2_to_esm(d: Alphabet): + # Remember that t is shifted from residue_constants by 1 (0 is padding). + esm_reorder = [d.padding_idx] + [ + d.get_idx(v) for v in residue_constants.restypes_with_x + ] + return torch.tensor(esm_reorder) + + def _af2_idx_to_esm_idx(self, aa, mask): + aa = (aa + 1).masked_fill(mask != 1, 0) + return self.af2_to_esm[aa] + + def _compute_language_model_representations( + self, esmaa: torch.Tensor + ) -> torch.Tensor: + """Adds bos/eos tokens for the language model, since the structure module doesn't use these.""" + batch_size = esmaa.size(0) + + bosi, eosi = self.esm_dict.cls_idx, self.esm_dict.eos_idx + bos = esmaa.new_full((batch_size, 1), bosi) + eos = esmaa.new_full((batch_size, 1), self.esm_dict.padding_idx) + esmaa = torch.cat([bos, esmaa, eos], dim=1) + # Use the first padding index as eos during inference. + esmaa[range(batch_size), (esmaa != 1).sum(1)] = eosi + + res = self.esm( + esmaa, + repr_layers=range(self.esm.num_layers + 1), + need_head_weights=self.cfg.use_esm_attn_map, + ) + esm_s = torch.stack( + [v for _, v in sorted(res["representations"].items())], dim=2 + ) + esm_s = esm_s[:, 1:-1] # B, L, nLayers, C + esm_z = ( + res["attentions"].permute(0, 4, 3, 1, 2).flatten(3, 4)[:, 1:-1, 1:-1, :] + if self.cfg.use_esm_attn_map + else None + ) + return esm_s, esm_z + + def _mask_inputs_to_esm(self, esmaa, pattern): + new_esmaa = esmaa.clone() + new_esmaa[pattern == 1] = self.esm_dict.mask_idx + return new_esmaa + + def forward( + self, + aa: torch.Tensor, + mask: T.Optional[torch.Tensor] = None, + residx: T.Optional[torch.Tensor] = None, + masking_pattern: T.Optional[torch.Tensor] = None, + num_recycles: T.Optional[int] = None, + ): + """Runs a forward pass given input tokens. Use `model.infer` to + run inference from a sequence. + + Args: + aa (torch.Tensor): Tensor containing indices corresponding to amino acids. Indices match + openfold.np.residue_constants.restype_order_with_x. + mask (torch.Tensor): Binary tensor with 1 meaning position is unmasked and 0 meaning position is masked. + residx (torch.Tensor): Residue indices of amino acids. Will assume contiguous if not provided. + masking_pattern (torch.Tensor): Optional masking to pass to the input. Binary tensor of the same size + as `aa`. Positions with 1 will be masked. ESMFold sometimes produces different samples when + different masks are provided. + num_recycles (int): How many recycle iterations to perform. If None, defaults to training max + recycles, which is 3. + """ + + if mask is None: + mask = torch.ones_like(aa) + + B = aa.shape[0] + L = aa.shape[1] + device = aa.device + + if residx is None: + residx = torch.arange(L, device=device).expand_as(aa) + + # === ESM === + esmaa = self._af2_idx_to_esm_idx(aa, mask) + + if masking_pattern is not None: + esmaa = self._mask_inputs_to_esm(esmaa, masking_pattern) + + esm_s, esm_z = self._compute_language_model_representations(esmaa) + + # Convert esm_s to the precision used by the trunk and + # the structure module. These tensors may be a lower precision if, for example, + # we're running the language model in fp16 precision. + esm_s = esm_s.to(self.esm_s_combine.dtype) + esm_s = esm_s.detach() + + # === preprocessing === + esm_s = (self.esm_s_combine.softmax(0).unsqueeze(0) @ esm_s).squeeze(2) + + s_s_0 = self.esm_s_mlp(esm_s) + if self.cfg.use_esm_attn_map: + esm_z = esm_z.to(self.esm_s_combine.dtype) + esm_z = esm_z.detach() + s_z_0 = self.esm_z_mlp(esm_z) + else: + s_z_0 = s_s_0.new_zeros(B, L, L, self.cfg.trunk.pairwise_state_dim) + + s_s_0 += self.embedding(aa) + + structure: dict = self.trunk( + s_s_0, s_z_0, aa, residx, mask, no_recycles=num_recycles + ) + # Documenting what we expect: + structure = { + k: v + for k, v in structure.items() + if k + in [ + "s_z", + "s_s", + "frames", + "sidechain_frames", + "unnormalized_angles", + "angles", + "positions", + "states", + ] + } + + disto_logits = self.distogram_head(structure["s_z"]) + disto_logits = (disto_logits + disto_logits.transpose(1, 2)) / 2 + structure["distogram_logits"] = disto_logits + + lm_logits = self.lm_head(structure["s_s"]) + structure["lm_logits"] = lm_logits + + structure["aatype"] = aa + make_atom14_masks(structure) + + for k in [ + "atom14_atom_exists", + "atom37_atom_exists", + ]: + structure[k] *= mask.unsqueeze(-1) + structure["residue_index"] = residx + + lddt_head = self.lddt_head(structure["states"]).reshape( + structure["states"].shape[0], B, L, -1, self.lddt_bins + ) + structure["lddt_head"] = lddt_head + plddt = categorical_lddt(lddt_head[-1], bins=self.lddt_bins) + structure["plddt"] = ( + 100 * plddt + ) # we predict plDDT between 0 and 1, scale to be between 0 and 100. + + ptm_logits = self.ptm_head(structure["s_z"]) + + seqlen = mask.type(torch.int64).sum(1) + structure["ptm_logits"] = ptm_logits + structure["ptm"] = torch.stack( + [ + compute_tm( + batch_ptm_logits[None, :sl, :sl], + max_bins=31, + no_bins=self.distogram_bins, + ) + for batch_ptm_logits, sl in zip(ptm_logits, seqlen) + ] + ) + structure.update( + compute_predicted_aligned_error( + ptm_logits, max_bin=31, no_bins=self.distogram_bins + ) + ) + + return structure + + @torch.no_grad() + def infer( + self, + sequences: T.Union[str, T.List[str]], + residx=None, + masking_pattern: T.Optional[torch.Tensor] = None, + num_recycles: T.Optional[int] = None, + residue_index_offset: T.Optional[int] = 512, + chain_linker: T.Optional[str] = "G" * 25, + ): + """Runs a forward pass given input sequences. + + Args: + sequences (Union[str, List[str]]): A list of sequences to make predictions for. Multimers can also be passed in, + each chain should be separated by a ':' token (e.g. "::"). + residx (torch.Tensor): Residue indices of amino acids. Will assume contiguous if not provided. + masking_pattern (torch.Tensor): Optional masking to pass to the input. Binary tensor of the same size + as `aa`. Positions with 1 will be masked. ESMFold sometimes produces different samples when + different masks are provided. + num_recycles (int): How many recycle iterations to perform. If None, defaults to training max + recycles (cfg.trunk.max_recycles), which is 4. + residue_index_offset (int): Residue index separation between chains if predicting a multimer. Has no effect on + single chain predictions. Default: 512. + chain_linker (str): Linker to use between chains if predicting a multimer. Has no effect on single chain + predictions. Default: length-25 poly-G ("G" * 25). + """ + if isinstance(sequences, str): + sequences = [sequences] + + aatype, mask, _residx, linker_mask, chain_index = batch_encode_sequences( + sequences, residue_index_offset, chain_linker + ) + + if residx is None: + residx = _residx + elif not isinstance(residx, torch.Tensor): + residx = collate_dense_tensors(residx) + + aatype, mask, residx, linker_mask = map( + lambda x: x.to(self.device), (aatype, mask, residx, linker_mask) + ) + + output = self.forward( + aatype, + mask=mask, + residx=residx, + masking_pattern=masking_pattern, + num_recycles=num_recycles, + ) + + output["atom37_atom_exists"] = output[ + "atom37_atom_exists" + ] * linker_mask.unsqueeze(2) + + output["mean_plddt"] = (output["plddt"] * output["atom37_atom_exists"]).sum( + dim=(1, 2) + ) / output["atom37_atom_exists"].sum(dim=(1, 2)) + output["chain_index"] = chain_index + + return output + + def output_to_pdb(self, output: T.Dict) -> T.List[str]: + """Returns the pbd (file) string from the model given the model output.""" + return output_to_pdb(output) + + def infer_pdbs(self, seqs: T.List[str], *args, **kwargs) -> T.List[str]: + """Returns list of pdb (files) strings from the model given a list of input sequences.""" + output = self.infer(seqs, *args, **kwargs) + return self.output_to_pdb(output) + + def infer_pdb(self, sequence: str, *args, **kwargs) -> str: + """Returns the pdb (file) string from the model given an input sequence.""" + return self.infer_pdbs([sequence], *args, **kwargs)[0] + + def set_chunk_size(self, chunk_size: T.Optional[int]): + # This parameter means the axial attention will be computed + # in a chunked manner. This should make the memory used more or less O(L) instead of O(L^2). + # It's equivalent to running a for loop over chunks of the dimension we're iterative over, + # where the chunk_size is the size of the chunks, so 128 would mean to parse 128-lengthed chunks. + # Setting the value to None will return to default behavior, disable chunking. + self.trunk.set_chunk_size(chunk_size) + + @property + def device(self): + return self.esm_s_combine.device diff --git a/esm/source/esm/esmfold/v1/misc.py b/esm/source/esm/esmfold/v1/misc.py new file mode 100644 index 0000000000000000000000000000000000000000..76b8e74cd73d44f68ea197fd15d5e2d38cbf8284 --- /dev/null +++ b/esm/source/esm/esmfold/v1/misc.py @@ -0,0 +1,309 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. +import typing as T + +import numpy as np +import torch +import torch.nn.functional as F +from einops import rearrange, repeat +from torch import nn +from openfold.np import residue_constants +from openfold.np.protein import Protein as OFProtein +from openfold.np.protein import to_pdb +from openfold.utils.feats import atom14_to_atom37 + + +def encode_sequence( + seq: str, + residue_index_offset: T.Optional[int] = 512, + chain_linker: T.Optional[str] = "G" * 25, +) -> T.Tuple[torch.Tensor, torch.Tensor, torch.Tensor, torch.Tensor]: + if chain_linker is None: + chain_linker = "" + if residue_index_offset is None: + residue_index_offset = 0 + + chains = seq.split(":") + seq = chain_linker.join(chains) + + unk_idx = residue_constants.restype_order_with_x["X"] + encoded = torch.tensor( + [residue_constants.restype_order_with_x.get(aa, unk_idx) for aa in seq] + ) + residx = torch.arange(len(encoded)) + + if residue_index_offset > 0: + start = 0 + for i, chain in enumerate(chains): + residx[start : start + len(chain) + len(chain_linker)] += ( + i * residue_index_offset + ) + start += len(chain) + len(chain_linker) + + linker_mask = torch.ones_like(encoded, dtype=torch.float32) + chain_index = [] + offset = 0 + for i, chain in enumerate(chains): + if i > 0: + chain_index.extend([i - 1] * len(chain_linker)) + chain_index.extend([i] * len(chain)) + offset += len(chain) + linker_mask[offset : offset + len(chain_linker)] = 0 + offset += len(chain_linker) + + chain_index = torch.tensor(chain_index, dtype=torch.int64) + + return encoded, residx, linker_mask, chain_index + + +def batch_encode_sequences( + sequences: T.Sequence[str], + residue_index_offset: T.Optional[int] = 512, + chain_linker: T.Optional[str] = "G" * 25, +) -> T.Tuple[torch.Tensor, torch.Tensor, torch.Tensor, torch.Tensor, torch.Tensor]: + + aatype_list = [] + residx_list = [] + linker_mask_list = [] + chain_index_list = [] + for seq in sequences: + aatype_seq, residx_seq, linker_mask_seq, chain_index_seq = encode_sequence( + seq, + residue_index_offset=residue_index_offset, + chain_linker=chain_linker, + ) + aatype_list.append(aatype_seq) + residx_list.append(residx_seq) + linker_mask_list.append(linker_mask_seq) + chain_index_list.append(chain_index_seq) + + aatype = collate_dense_tensors(aatype_list) + mask = collate_dense_tensors( + [aatype.new_ones(len(aatype_seq)) for aatype_seq in aatype_list] + ) + residx = collate_dense_tensors(residx_list) + linker_mask = collate_dense_tensors(linker_mask_list) + chain_index_list = collate_dense_tensors(chain_index_list, -1) + + return aatype, mask, residx, linker_mask, chain_index_list + + +def output_to_pdb(output: T.Dict) -> T.List[str]: + """Returns the pbd (file) string from the model given the model output.""" + # atom14_to_atom37 must be called first, as it fails on latest numpy if the + # input is a numpy array. It will work if the input is a torch tensor. + final_atom_positions = atom14_to_atom37(output["positions"][-1], output) + output = {k: v.to("cpu").numpy() for k, v in output.items()} + final_atom_positions = final_atom_positions.cpu().numpy() + final_atom_mask = output["atom37_atom_exists"] + pdbs = [] + for i in range(output["aatype"].shape[0]): + aa = output["aatype"][i] + pred_pos = final_atom_positions[i] + mask = final_atom_mask[i] + resid = output["residue_index"][i] + 1 + pred = OFProtein( + aatype=aa, + atom_positions=pred_pos, + atom_mask=mask, + residue_index=resid, + b_factors=output["plddt"][i], + chain_index=output["chain_index"][i] if "chain_index" in output else None, + ) + pdbs.append(to_pdb(pred)) + return pdbs + + +def collate_dense_tensors( + samples: T.List[torch.Tensor], pad_v: float = 0 +) -> torch.Tensor: + """ + Takes a list of tensors with the following dimensions: + [(d_11, ..., d_1K), + (d_21, ..., d_2K), + ..., + (d_N1, ..., d_NK)] + and stack + pads them into a single tensor of: + (N, max_i=1,N { d_i1 }, ..., max_i=1,N {diK}) + """ + if len(samples) == 0: + return torch.Tensor() + if len(set(x.dim() for x in samples)) != 1: + raise RuntimeError( + f"Samples has varying dimensions: {[x.dim() for x in samples]}" + ) + (device,) = tuple(set(x.device for x in samples)) # assumes all on same device + max_shape = [max(lst) for lst in zip(*[x.shape for x in samples])] + result = torch.empty( + len(samples), *max_shape, dtype=samples[0].dtype, device=device + ) + result.fill_(pad_v) + for i in range(len(samples)): + result_i = result[i] + t = samples[i] + result_i[tuple(slice(0, k) for k in t.shape)] = t + return result + + +class Attention(nn.Module): + def __init__(self, embed_dim, num_heads, head_width, gated=False): + super().__init__() + assert embed_dim == num_heads * head_width + + self.embed_dim = embed_dim + self.num_heads = num_heads + self.head_width = head_width + + self.proj = nn.Linear(embed_dim, embed_dim * 3, bias=False) + self.o_proj = nn.Linear(embed_dim, embed_dim, bias=True) + self.gated = gated + if gated: + self.g_proj = nn.Linear(embed_dim, embed_dim) + torch.nn.init.zeros_(self.g_proj.weight) + torch.nn.init.ones_(self.g_proj.bias) + + self.rescale_factor = self.head_width**-0.5 + + torch.nn.init.zeros_(self.o_proj.bias) + + def forward(self, x, mask=None, bias=None, indices=None): + """ + Basic self attention with optional mask and external pairwise bias. + To handle sequences of different lengths, use mask. + + Inputs: + x: batch of input sequneces (.. x L x C) + mask: batch of boolean masks where 1=valid, 0=padding position (.. x L_k). optional. + bias: batch of scalar pairwise attention biases (.. x Lq x Lk x num_heads). optional. + + Outputs: + sequence projection (B x L x embed_dim), attention maps (B x L x L x num_heads) + """ + + t = rearrange(self.proj(x), "... l (h c) -> ... h l c", h=self.num_heads) + q, k, v = t.chunk(3, dim=-1) + + q = self.rescale_factor * q + a = torch.einsum("...qc,...kc->...qk", q, k) + + # Add external attention bias. + if bias is not None: + a = a + rearrange(bias, "... lq lk h -> ... h lq lk") + + # Do not attend to padding tokens. + if mask is not None: + mask = repeat( + mask, "... lk -> ... h lq lk", h=self.num_heads, lq=q.shape[-2] + ) + a = a.masked_fill(mask == False, -np.inf) + + a = F.softmax(a, dim=-1) + + y = torch.einsum("...hqk,...hkc->...qhc", a, v) + y = rearrange(y, "... h c -> ... (h c)", h=self.num_heads) + + if self.gated: + y = self.g_proj(x).sigmoid() * y + y = self.o_proj(y) + + return y, rearrange(a, "... lq lk h -> ... h lq lk") + + +class Dropout(nn.Module): + """ + Implementation of dropout with the ability to share the dropout mask + along a particular dimension. + """ + + def __init__(self, r: float, batch_dim: T.Union[int, T.List[int]]): + super(Dropout, self).__init__() + + self.r = r + if type(batch_dim) == int: + batch_dim = [batch_dim] + self.batch_dim = batch_dim + self.dropout = nn.Dropout(self.r) + + def forward(self, x: torch.Tensor) -> torch.Tensor: + shape = list(x.shape) + if self.batch_dim is not None: + for bd in self.batch_dim: + shape[bd] = 1 + return x * self.dropout(x.new_ones(shape)) + + +class SequenceToPair(nn.Module): + def __init__(self, sequence_state_dim, inner_dim, pairwise_state_dim): + super().__init__() + + self.layernorm = nn.LayerNorm(sequence_state_dim) + self.proj = nn.Linear(sequence_state_dim, inner_dim * 2, bias=True) + self.o_proj = nn.Linear(2 * inner_dim, pairwise_state_dim, bias=True) + + torch.nn.init.zeros_(self.proj.bias) + torch.nn.init.zeros_(self.o_proj.bias) + + def forward(self, sequence_state): + """ + Inputs: + sequence_state: B x L x sequence_state_dim + + Output: + pairwise_state: B x L x L x pairwise_state_dim + + Intermediate state: + B x L x L x 2*inner_dim + """ + + assert len(sequence_state.shape) == 3 + + s = self.layernorm(sequence_state) + s = self.proj(s) + q, k = s.chunk(2, dim=-1) + + prod = q[:, None, :, :] * k[:, :, None, :] + diff = q[:, None, :, :] - k[:, :, None, :] + + x = torch.cat([prod, diff], dim=-1) + x = self.o_proj(x) + + return x + + +class PairToSequence(nn.Module): + def __init__(self, pairwise_state_dim, num_heads): + super().__init__() + + self.layernorm = nn.LayerNorm(pairwise_state_dim) + self.linear = nn.Linear(pairwise_state_dim, num_heads, bias=False) + + def forward(self, pairwise_state): + """ + Inputs: + pairwise_state: B x L x L x pairwise_state_dim + + Output: + pairwise_bias: B x L x L x num_heads + """ + assert len(pairwise_state.shape) == 4 + z = self.layernorm(pairwise_state) + pairwise_bias = self.linear(z) + return pairwise_bias + + +class ResidueMLP(nn.Module): + def __init__(self, embed_dim, inner_dim, norm=nn.LayerNorm, dropout=0): + super().__init__() + + self.mlp = nn.Sequential( + norm(embed_dim), + nn.Linear(embed_dim, inner_dim), + nn.ReLU(), + nn.Linear(inner_dim, embed_dim), + nn.Dropout(dropout), + ) + + def forward(self, x): + return x + self.mlp(x) diff --git a/esm/source/esm/esmfold/v1/pretrained.py b/esm/source/esm/esmfold/v1/pretrained.py new file mode 100644 index 0000000000000000000000000000000000000000..1dc7b8527cfd460a9c97a0aeae6af837f13f220a --- /dev/null +++ b/esm/source/esm/esmfold/v1/pretrained.py @@ -0,0 +1,181 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from pathlib import Path + +import torch + +from esm.esmfold.v1.esmfold import ESMFold + + +def _load_model(model_name): + if model_name.endswith(".pt"): # local, treat as filepath + model_path = Path(model_name) + model_data = torch.load(str(model_path), map_location="cpu") + else: # load from hub + url = f"https://dl.fbaipublicfiles.com/fair-esm/models/{model_name}.pt" + model_data = torch.hub.load_state_dict_from_url(url, progress=False, map_location="cpu") + + cfg = model_data["cfg"]["model"] + model_state = model_data["model"] + model = ESMFold(esmfold_config=cfg) + + expected_keys = set(model.state_dict().keys()) + found_keys = set(model_state.keys()) + + missing_essential_keys = [] + for missing_key in expected_keys - found_keys: + if not missing_key.startswith("esm."): + missing_essential_keys.append(missing_key) + + if missing_essential_keys: + raise RuntimeError(f"Keys '{', '.join(missing_essential_keys)}' are missing.") + + model.load_state_dict(model_state, strict=False) + + return model + + +def esmfold_v0(): + """ + ESMFold v0 model with 3B ESM-2, 48 folding blocks. + This version was used for the paper (Lin et al, 2022). It was trained + on all PDB chains until 2020-05, to ensure temporal holdout with CASP14 + and the CAMEO validation and test set reported there. + """ + return _load_model("esmfold_3B_v0") + + +def esmfold_v1(): + """ + ESMFold v1 model using 3B ESM-2, 48 folding blocks. + ESMFold provides fast high accuracy atomic level structure prediction + directly from the individual sequence of a protein. ESMFold uses the ESM2 + protein language model to extract meaningful representations from the + protein sequence. + """ + return _load_model("esmfold_3B_v1") + + +def esmfold_structure_module_only_8M(): + """ + ESMFold baseline model using 8M ESM-2, 0 folding blocks. + ESM-2 here is trained out to 500K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + return _load_model("esmfold_structure_module_only_8M") + + +def esmfold_structure_module_only_8M_270K(): + """ + ESMFold baseline model using 8M ESM-2, 0 folding blocks. + ESM-2 here is trained out to 270K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + return _load_model("esmfold_structure_module_only_8M_270K") + + +def esmfold_structure_module_only_35M(): + """ + ESMFold baseline model using 35M ESM-2, 0 folding blocks. + ESM-2 here is trained out to 500K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + return _load_model("esmfold_structure_module_only_35M") + + +def esmfold_structure_module_only_35M_270K(): + """ + ESMFold baseline model using 35M ESM-2, 0 folding blocks. + ESM-2 here is trained out to 270K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + return _load_model("esmfold_structure_module_only_35M_270K") + + +def esmfold_structure_module_only_150M(): + """ + ESMFold baseline model using 150M ESM-2, 0 folding blocks. + ESM-2 here is trained out to 500K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + return _load_model("esmfold_structure_module_only_150M") + + +def esmfold_structure_module_only_150M_270K(): + """ + ESMFold baseline model using 150M ESM-2, 0 folding blocks. + ESM-2 here is trained out to 270K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + return _load_model("esmfold_structure_module_only_150M_270K") + + +def esmfold_structure_module_only_650M(): + """ + ESMFold baseline model using 650M ESM-2, 0 folding blocks. + ESM-2 here is trained out to 500K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + return _load_model("esmfold_structure_module_only_650M") + + +def esmfold_structure_module_only_650M_270K(): + """ + ESMFold baseline model using 650M ESM-2, 0 folding blocks. + ESM-2 here is trained out to 270K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + return _load_model("esmfold_structure_module_only_650M_270K") + + +def esmfold_structure_module_only_3B(): + """ + ESMFold baseline model using 3B ESM-2, 0 folding blocks. + ESM-2 here is trained out to 500K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + return _load_model("esmfold_structure_module_only_3B") + + +def esmfold_structure_module_only_3B_270K(): + """ + ESMFold baseline model using 3B ESM-2, 0 folding blocks. + ESM-2 here is trained out to 270K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + return _load_model("esmfold_structure_module_only_3B_270K") + + +def esmfold_structure_module_only_15B(): + """ + ESMFold baseline model using 15B ESM-2, 0 folding blocks. + ESM-2 here is trained out to 270K updates. + The 15B parameter ESM-2 was not trained out to 500K updates + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + return _load_model("esmfold_structure_module_only_15B") diff --git a/esm/source/esm/esmfold/v1/tri_self_attn_block.py b/esm/source/esm/esmfold/v1/tri_self_attn_block.py new file mode 100644 index 0000000000000000000000000000000000000000..b27ba480cecc964896659de69130524be054ad37 --- /dev/null +++ b/esm/source/esm/esmfold/v1/tri_self_attn_block.py @@ -0,0 +1,160 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. +import torch +from openfold.model.triangular_attention import ( + TriangleAttentionEndingNode, + TriangleAttentionStartingNode, +) +from openfold.model.triangular_multiplicative_update import ( + TriangleMultiplicationIncoming, + TriangleMultiplicationOutgoing, +) +from torch import nn + +from esm.esmfold.v1.misc import ( + Attention, + Dropout, + PairToSequence, + ResidueMLP, + SequenceToPair, +) + + +class TriangularSelfAttentionBlock(nn.Module): + def __init__( + self, + sequence_state_dim, + pairwise_state_dim, + sequence_head_width, + pairwise_head_width, + dropout=0, + **__kwargs, + ): + super().__init__() + + assert sequence_state_dim % sequence_head_width == 0 + assert pairwise_state_dim % pairwise_head_width == 0 + sequence_num_heads = sequence_state_dim // sequence_head_width + pairwise_num_heads = pairwise_state_dim // pairwise_head_width + assert sequence_state_dim == sequence_num_heads * sequence_head_width + assert pairwise_state_dim == pairwise_num_heads * pairwise_head_width + assert pairwise_state_dim % 2 == 0 + + self.sequence_state_dim = sequence_state_dim + self.pairwise_state_dim = pairwise_state_dim + + self.layernorm_1 = nn.LayerNorm(sequence_state_dim) + + self.sequence_to_pair = SequenceToPair( + sequence_state_dim, pairwise_state_dim // 2, pairwise_state_dim + ) + self.pair_to_sequence = PairToSequence(pairwise_state_dim, sequence_num_heads) + + self.seq_attention = Attention( + sequence_state_dim, sequence_num_heads, sequence_head_width, gated=True + ) + self.tri_mul_out = TriangleMultiplicationOutgoing( + pairwise_state_dim, + pairwise_state_dim, + ) + self.tri_mul_in = TriangleMultiplicationIncoming( + pairwise_state_dim, + pairwise_state_dim, + ) + self.tri_att_start = TriangleAttentionStartingNode( + pairwise_state_dim, + pairwise_head_width, + pairwise_num_heads, + inf=1e9, + ) # type: ignore + self.tri_att_end = TriangleAttentionEndingNode( + pairwise_state_dim, + pairwise_head_width, + pairwise_num_heads, + inf=1e9, + ) # type: ignore + + self.mlp_seq = ResidueMLP(sequence_state_dim, 4 * sequence_state_dim, dropout=dropout) + self.mlp_pair = ResidueMLP(pairwise_state_dim, 4 * pairwise_state_dim, dropout=dropout) + + assert dropout < 0.4 + self.drop = nn.Dropout(dropout) + self.row_drop = Dropout(dropout * 2, 2) + self.col_drop = Dropout(dropout * 2, 1) + + torch.nn.init.zeros_(self.tri_mul_in.linear_z.weight) + torch.nn.init.zeros_(self.tri_mul_in.linear_z.bias) + torch.nn.init.zeros_(self.tri_mul_out.linear_z.weight) + torch.nn.init.zeros_(self.tri_mul_out.linear_z.bias) + torch.nn.init.zeros_(self.tri_att_start.mha.linear_o.weight) + torch.nn.init.zeros_(self.tri_att_start.mha.linear_o.bias) + torch.nn.init.zeros_(self.tri_att_end.mha.linear_o.weight) + torch.nn.init.zeros_(self.tri_att_end.mha.linear_o.bias) + + torch.nn.init.zeros_(self.sequence_to_pair.o_proj.weight) + torch.nn.init.zeros_(self.sequence_to_pair.o_proj.bias) + torch.nn.init.zeros_(self.pair_to_sequence.linear.weight) + torch.nn.init.zeros_(self.seq_attention.o_proj.weight) + torch.nn.init.zeros_(self.seq_attention.o_proj.bias) + torch.nn.init.zeros_(self.mlp_seq.mlp[-2].weight) + torch.nn.init.zeros_(self.mlp_seq.mlp[-2].bias) + torch.nn.init.zeros_(self.mlp_pair.mlp[-2].weight) + torch.nn.init.zeros_(self.mlp_pair.mlp[-2].bias) + + def forward(self, sequence_state, pairwise_state, mask=None, chunk_size=None, **__kwargs): + """ + Inputs: + sequence_state: B x L x sequence_state_dim + pairwise_state: B x L x L x pairwise_state_dim + mask: B x L boolean tensor of valid positions + + Output: + sequence_state: B x L x sequence_state_dim + pairwise_state: B x L x L x pairwise_state_dim + """ + assert len(sequence_state.shape) == 3 + assert len(pairwise_state.shape) == 4 + if mask is not None: + assert len(mask.shape) == 2 + + batch_dim, seq_dim, sequence_state_dim = sequence_state.shape + pairwise_state_dim = pairwise_state.shape[3] + assert sequence_state_dim == self.sequence_state_dim + assert pairwise_state_dim == self.pairwise_state_dim + assert batch_dim == pairwise_state.shape[0] + assert seq_dim == pairwise_state.shape[1] + assert seq_dim == pairwise_state.shape[2] + + # Update sequence state + bias = self.pair_to_sequence(pairwise_state) + + # Self attention with bias + mlp. + y = self.layernorm_1(sequence_state) + y, _ = self.seq_attention(y, mask=mask, bias=bias) + sequence_state = sequence_state + self.drop(y) + sequence_state = self.mlp_seq(sequence_state) + + # Update pairwise state + pairwise_state = pairwise_state + self.sequence_to_pair(sequence_state) + + # Axial attention with triangular bias. + tri_mask = mask.unsqueeze(2) * mask.unsqueeze(1) if mask is not None else None + pairwise_state = pairwise_state + self.row_drop( + self.tri_mul_out(pairwise_state, mask=tri_mask) + ) + pairwise_state = pairwise_state + self.col_drop( + self.tri_mul_in(pairwise_state, mask=tri_mask) + ) + pairwise_state = pairwise_state + self.row_drop( + self.tri_att_start(pairwise_state, mask=tri_mask, chunk_size=chunk_size) + ) + pairwise_state = pairwise_state + self.col_drop( + self.tri_att_end(pairwise_state, mask=tri_mask, chunk_size=chunk_size) + ) + + # MLP over pairs. + pairwise_state = self.mlp_pair(pairwise_state) + + return sequence_state, pairwise_state diff --git a/esm/source/esm/esmfold/v1/trunk.py b/esm/source/esm/esmfold/v1/trunk.py new file mode 100644 index 0000000000000000000000000000000000000000..9b5ee192203d8f673722023989c46523a1947678 --- /dev/null +++ b/esm/source/esm/esmfold/v1/trunk.py @@ -0,0 +1,243 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. +import typing as T +from contextlib import ExitStack +from dataclasses import dataclass + +import torch +import torch.nn as nn +from openfold.model.structure_module import StructureModule + +from esm.esmfold.v1.tri_self_attn_block import TriangularSelfAttentionBlock + + +@dataclass +class StructureModuleConfig: + c_s: int = 384 + c_z: int = 128 + c_ipa: int = 16 + c_resnet: int = 128 + no_heads_ipa: int = 12 + no_qk_points: int = 4 + no_v_points: int = 8 + dropout_rate: float = 0.1 + no_blocks: int = 8 + no_transition_layers: int = 1 + no_resnet_blocks: int = 2 + no_angles: int = 7 + trans_scale_factor: int = 10 + epsilon: float = 1e-8 + inf: float = 1e5 + + +@dataclass +class FoldingTrunkConfig: + _name: str = "FoldingTrunkConfig" + num_blocks: int = 48 + sequence_state_dim: int = 1024 + pairwise_state_dim: int = 128 + sequence_head_width: int = 32 + pairwise_head_width: int = 32 + position_bins: int = 32 + dropout: float = 0 + layer_drop: float = 0 + cpu_grad_checkpoint: bool = False + + max_recycles: int = 4 + chunk_size: T.Optional[int] = None + + structure_module: StructureModuleConfig = StructureModuleConfig() + + +def get_axial_mask(mask): + """ + Helper to convert B x L mask of valid positions to axial mask used + in row column attentions. + + Input: + mask: B x L tensor of booleans + + Output: + mask: B x L x L tensor of booleans + """ + + if mask is None: + return None + assert len(mask.shape) == 2 + batch_dim, seq_dim = mask.shape + m = mask.unsqueeze(1).expand(batch_dim, seq_dim, seq_dim) + m = m.reshape(batch_dim * seq_dim, seq_dim) + return m + + +class RelativePosition(nn.Module): + def __init__(self, bins, pairwise_state_dim): + super().__init__() + self.bins = bins + + # Note an additional offset is used so that the 0th position + # is reserved for masked pairs. + self.embedding = torch.nn.Embedding(2 * bins + 2, pairwise_state_dim) + + def forward(self, residue_index, mask=None): + """ + Input: + residue_index: B x L tensor of indices (dytpe=torch.long) + mask: B x L tensor of booleans + + Output: + pairwise_state: B x L x L x pairwise_state_dim tensor of embeddings + """ + + assert residue_index.dtype == torch.long + if mask is not None: + assert residue_index.shape == mask.shape + + diff = residue_index[:, None, :] - residue_index[:, :, None] + diff = diff.clamp(-self.bins, self.bins) + diff = diff + self.bins + 1 # Add 1 to adjust for padding index. + + if mask is not None: + mask = mask[:, None, :] * mask[:, :, None] + diff[mask == False] = 0 + + output = self.embedding(diff) + return output + + +class FoldingTrunk(nn.Module): + def __init__(self, **kwargs): + super().__init__() + self.cfg = FoldingTrunkConfig(**kwargs) + assert self.cfg.max_recycles > 0 + + c_s = self.cfg.sequence_state_dim + c_z = self.cfg.pairwise_state_dim + + assert c_s % self.cfg.sequence_head_width == 0 + assert c_z % self.cfg.pairwise_head_width == 0 + block = TriangularSelfAttentionBlock + + self.pairwise_positional_embedding = RelativePosition(self.cfg.position_bins, c_z) + + self.blocks = nn.ModuleList( + [ + block( + sequence_state_dim=c_s, + pairwise_state_dim=c_z, + sequence_head_width=self.cfg.sequence_head_width, + pairwise_head_width=self.cfg.pairwise_head_width, + dropout=self.cfg.dropout, + ) + for i in range(self.cfg.num_blocks) + ] + ) + + self.recycle_bins = 15 + self.recycle_s_norm = nn.LayerNorm(c_s) + self.recycle_z_norm = nn.LayerNorm(c_z) + self.recycle_disto = nn.Embedding(self.recycle_bins, c_z) + self.recycle_disto.weight[0].detach().zero_() + + self.structure_module = StructureModule(**self.cfg.structure_module) # type: ignore + self.trunk2sm_s = nn.Linear(c_s, self.structure_module.c_s) + self.trunk2sm_z = nn.Linear(c_z, self.structure_module.c_z) + + self.chunk_size = self.cfg.chunk_size + + def set_chunk_size(self, chunk_size): + # This parameter means the axial attention will be computed + # in a chunked manner. This should make the memory used more or less O(L) instead of O(L^2). + # It's equivalent to running a for loop over chunks of the dimension we're iterative over, + # where the chunk_size is the size of the chunks, so 128 would mean to parse 128-lengthed chunks. + self.chunk_size = chunk_size + + def forward(self, seq_feats, pair_feats, true_aa, residx, mask, no_recycles: T.Optional[int] = None): + """ + Inputs: + seq_feats: B x L x C tensor of sequence features + pair_feats: B x L x L x C tensor of pair features + residx: B x L long tensor giving the position in the sequence + mask: B x L boolean tensor indicating valid residues + + Output: + predicted_structure: B x L x (num_atoms_per_residue * 3) tensor wrapped in a Coordinates object + """ + + device = seq_feats.device + s_s_0 = seq_feats + s_z_0 = pair_feats + + if no_recycles is None: + no_recycles = self.cfg.max_recycles + else: + assert no_recycles >= 0, "Number of recycles must not be negative." + no_recycles += 1 # First 'recycle' is just the standard forward pass through the model. + + def trunk_iter(s, z, residx, mask): + z = z + self.pairwise_positional_embedding(residx, mask=mask) + + for block in self.blocks: + s, z = block(s, z, mask=mask, residue_index=residx, chunk_size=self.chunk_size) + return s, z + + s_s = s_s_0 + s_z = s_z_0 + recycle_s = torch.zeros_like(s_s) + recycle_z = torch.zeros_like(s_z) + recycle_bins = torch.zeros(*s_z.shape[:-1], device=device, dtype=torch.int64) + + assert no_recycles > 0 + for recycle_idx in range(no_recycles): + with ExitStack() if recycle_idx == no_recycles - 1 else torch.no_grad(): + # === Recycling === + recycle_s = self.recycle_s_norm(recycle_s.detach()) + recycle_z = self.recycle_z_norm(recycle_z.detach()) + recycle_z += self.recycle_disto(recycle_bins.detach()) + + s_s, s_z = trunk_iter(s_s_0 + recycle_s, s_z_0 + recycle_z, residx, mask) + + # === Structure module === + structure = self.structure_module( + {"single": self.trunk2sm_s(s_s), "pair": self.trunk2sm_z(s_z)}, + true_aa, + mask.float(), + ) + + recycle_s = s_s + recycle_z = s_z + # Distogram needs the N, CA, C coordinates, and bin constants same as alphafold. + recycle_bins = FoldingTrunk.distogram( + structure["positions"][-1][:, :, :3], + 3.375, + 21.375, + self.recycle_bins, + ) + + assert isinstance(structure, dict) # type: ignore + structure["s_s"] = s_s + structure["s_z"] = s_z + + return structure + + @staticmethod + def distogram(coords, min_bin, max_bin, num_bins): + # Coords are [... L x 3 x 3], where it's [N, CA, C] x 3 coordinates. + boundaries = torch.linspace( + min_bin, + max_bin, + num_bins - 1, + device=coords.device, + ) + boundaries = boundaries**2 + N, CA, C = [x.squeeze(-2) for x in coords.chunk(3, dim=-2)] + # Infer CB coordinates. + b = CA - N + c = C - CA + a = b.cross(c, dim=-1) + CB = -0.58273431 * a + 0.56802827 * b - 0.54067466 * c + CA + dists = (CB[..., None, :, :] - CB[..., :, None, :]).pow(2).sum(dim=-1, keepdims=True) + bins = torch.sum(dists > boundaries, dim=-1) # [..., L, L] + return bins diff --git a/esm/source/esm/inverse_folding/__init__.py b/esm/source/esm/inverse_folding/__init__.py new file mode 100644 index 0000000000000000000000000000000000000000..2906fc5a84b8c3cf64af778f8c78938d57d2f7da --- /dev/null +++ b/esm/source/esm/inverse_folding/__init__.py @@ -0,0 +1,8 @@ +# Copyright (c) Facebook, Inc. and its affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from . import gvp_transformer +from . import util +from . import multichain_util diff --git a/esm/source/esm/inverse_folding/features.py b/esm/source/esm/inverse_folding/features.py new file mode 100644 index 0000000000000000000000000000000000000000..f67f3fe8d122b30162fcb4c136f65f2886150431 --- /dev/null +++ b/esm/source/esm/inverse_folding/features.py @@ -0,0 +1,352 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. +# +# Portions of this file were adapted from the open source code for the following +# two papers: +# +# Ingraham, J., Garg, V., Barzilay, R., & Jaakkola, T. (2019). Generative +# models for graph-based protein design. Advances in Neural Information +# Processing Systems, 32. +# +# Jing, B., Eismann, S., Suriana, P., Townshend, R. J. L., & Dror, R. (2020). +# Learning from Protein Structure with Geometric Vector Perceptrons. In +# International Conference on Learning Representations. +# +# MIT License +# +# Copyright (c) 2020 Bowen Jing, Stephan Eismann, Patricia Suriana, Raphael Townshend, Ron Dror +# +# Permission is hereby granted, free of charge, to any person obtaining a copy +# of this software and associated documentation files (the "Software"), to deal +# in the Software without restriction, including without limitation the rights +# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +# copies of the Software, and to permit persons to whom the Software is +# furnished to do so, subject to the following conditions: +# +# The above copyright notice and this permission notice shall be included in all +# copies or substantial portions of the Software. +# +# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +# AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +# OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE +# SOFTWARE. +# +# ================================================================ +# The below license applies to the portions of the code (parts of +# src/datasets.py and src/models.py) adapted from Ingraham, et al. +# ================================================================ +# +# MIT License +# +# Copyright (c) 2019 John Ingraham, Vikas Garg, Regina Barzilay, Tommi Jaakkola +# +# Permission is hereby granted, free of charge, to any person obtaining a copy +# of this software and associated documentation files (the "Software"), to deal +# in the Software without restriction, including without limitation the rights +# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +# copies of the Software, and to permit persons to whom the Software is +# furnished to do so, subject to the following conditions: +# +# The above copyright notice and this permission notice shall be included in all +# copies or substantial portions of the Software. +# +# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +# AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +# OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE +# SOFTWARE. + +import math +import numpy as np +import torch +import torch.nn as nn +import torch.nn.functional as F + +from .gvp_utils import flatten_graph +from .gvp_modules import GVP, LayerNorm +from .util import normalize, norm, nan_to_num, rbf + + +class GVPInputFeaturizer(nn.Module): + + @staticmethod + def get_node_features(coords, coord_mask, with_coord_mask=True): + # scalar features + node_scalar_features = GVPInputFeaturizer._dihedrals(coords) + if with_coord_mask: + node_scalar_features = torch.cat([ + node_scalar_features, + coord_mask.float().unsqueeze(-1) + ], dim=-1) + # vector features + X_ca = coords[:, :, 1] + orientations = GVPInputFeaturizer._orientations(X_ca) + sidechains = GVPInputFeaturizer._sidechains(coords) + node_vector_features = torch.cat([orientations, sidechains.unsqueeze(-2)], dim=-2) + return node_scalar_features, node_vector_features + + @staticmethod + def _orientations(X): + forward = normalize(X[:, 1:] - X[:, :-1]) + backward = normalize(X[:, :-1] - X[:, 1:]) + forward = F.pad(forward, [0, 0, 0, 1]) + backward = F.pad(backward, [0, 0, 1, 0]) + return torch.cat([forward.unsqueeze(-2), backward.unsqueeze(-2)], -2) + + @staticmethod + def _sidechains(X): + n, origin, c = X[:, :, 0], X[:, :, 1], X[:, :, 2] + c, n = normalize(c - origin), normalize(n - origin) + bisector = normalize(c + n) + perp = normalize(torch.cross(c, n, dim=-1)) + vec = -bisector * math.sqrt(1 / 3) - perp * math.sqrt(2 / 3) + return vec + + @staticmethod + def _dihedrals(X, eps=1e-7): + X = torch.flatten(X[:, :, :3], 1, 2) + bsz = X.shape[0] + dX = X[:, 1:] - X[:, :-1] + U = normalize(dX, dim=-1) + u_2 = U[:, :-2] + u_1 = U[:, 1:-1] + u_0 = U[:, 2:] + + # Backbone normals + n_2 = normalize(torch.cross(u_2, u_1, dim=-1), dim=-1) + n_1 = normalize(torch.cross(u_1, u_0, dim=-1), dim=-1) + + # Angle between normals + cosD = torch.sum(n_2 * n_1, -1) + cosD = torch.clamp(cosD, -1 + eps, 1 - eps) + D = torch.sign(torch.sum(u_2 * n_1, -1)) * torch.acos(cosD) + + # This scheme will remove phi[0], psi[-1], omega[-1] + D = F.pad(D, [1, 2]) + D = torch.reshape(D, [bsz, -1, 3]) + # Lift angle representations to the circle + D_features = torch.cat([torch.cos(D), torch.sin(D)], -1) + return D_features + + @staticmethod + def _positional_embeddings(edge_index, + num_embeddings=None, + num_positional_embeddings=16, + period_range=[2, 1000]): + # From https://github.com/jingraham/neurips19-graph-protein-design + num_embeddings = num_embeddings or num_positional_embeddings + d = edge_index[0] - edge_index[1] + + frequency = torch.exp( + torch.arange(0, num_embeddings, 2, dtype=torch.float32, + device=edge_index.device) + * -(np.log(10000.0) / num_embeddings) + ) + angles = d.unsqueeze(-1) * frequency + E = torch.cat((torch.cos(angles), torch.sin(angles)), -1) + return E + + @staticmethod + def _dist(X, coord_mask, padding_mask, top_k_neighbors, eps=1e-8): + """ Pairwise euclidean distances """ + bsz, maxlen = X.size(0), X.size(1) + coord_mask_2D = torch.unsqueeze(coord_mask,1) * torch.unsqueeze(coord_mask,2) + residue_mask = ~padding_mask + residue_mask_2D = torch.unsqueeze(residue_mask,1) * torch.unsqueeze(residue_mask,2) + dX = torch.unsqueeze(X,1) - torch.unsqueeze(X,2) + D = coord_mask_2D * norm(dX, dim=-1) + + # sorting preference: first those with coords, then among the residues that + # exist but are masked use distance in sequence as tie breaker, and then the + # residues that came from padding are last + seqpos = torch.arange(maxlen, device=X.device) + Dseq = torch.abs(seqpos.unsqueeze(1) - seqpos.unsqueeze(0)).repeat(bsz, 1, 1) + D_adjust = nan_to_num(D) + (~coord_mask_2D) * (1e8 + Dseq*1e6) + ( + ~residue_mask_2D) * (1e10) + + if top_k_neighbors == -1: + D_neighbors = D_adjust + E_idx = seqpos.repeat( + *D_neighbors.shape[:-1], 1) + else: + # Identify k nearest neighbors (including self) + k = min(top_k_neighbors, X.size(1)) + D_neighbors, E_idx = torch.topk(D_adjust, k, dim=-1, largest=False) + + coord_mask_neighbors = (D_neighbors < 5e7) + residue_mask_neighbors = (D_neighbors < 5e9) + return D_neighbors, E_idx, coord_mask_neighbors, residue_mask_neighbors + + +class Normalize(nn.Module): + def __init__(self, features, epsilon=1e-6): + super(Normalize, self).__init__() + self.gain = nn.Parameter(torch.ones(features)) + self.bias = nn.Parameter(torch.zeros(features)) + self.epsilon = epsilon + + def forward(self, x, dim=-1): + mu = x.mean(dim, keepdim=True) + sigma = torch.sqrt(x.var(dim, keepdim=True) + self.epsilon) + gain = self.gain + bias = self.bias + # Reshape + if dim != -1: + shape = [1] * len(mu.size()) + shape[dim] = self.gain.size()[0] + gain = gain.view(shape) + bias = bias.view(shape) + return gain * (x - mu) / (sigma + self.epsilon) + bias + + +class DihedralFeatures(nn.Module): + def __init__(self, node_embed_dim): + """ Embed dihedral angle features. """ + super(DihedralFeatures, self).__init__() + # 3 dihedral angles; sin and cos of each angle + node_in = 6 + # Normalization and embedding + self.node_embedding = nn.Linear(node_in, node_embed_dim, bias=True) + self.norm_nodes = Normalize(node_embed_dim) + + def forward(self, X): + """ Featurize coordinates as an attributed graph """ + V = self._dihedrals(X) + V = self.node_embedding(V) + V = self.norm_nodes(V) + return V + + @staticmethod + def _dihedrals(X, eps=1e-7, return_angles=False): + # First 3 coordinates are N, CA, C + X = X[:,:,:3,:].reshape(X.shape[0], 3*X.shape[1], 3) + + # Shifted slices of unit vectors + dX = X[:,1:,:] - X[:,:-1,:] + U = F.normalize(dX, dim=-1) + u_2 = U[:,:-2,:] + u_1 = U[:,1:-1,:] + u_0 = U[:,2:,:] + # Backbone normals + n_2 = F.normalize(torch.cross(u_2, u_1, dim=-1), dim=-1) + n_1 = F.normalize(torch.cross(u_1, u_0, dim=-1), dim=-1) + + # Angle between normals + cosD = (n_2 * n_1).sum(-1) + cosD = torch.clamp(cosD, -1+eps, 1-eps) + D = torch.sign((u_2 * n_1).sum(-1)) * torch.acos(cosD) + + # This scheme will remove phi[0], psi[-1], omega[-1] + D = F.pad(D, (1,2), 'constant', 0) + D = D.view((D.size(0), int(D.size(1)/3), 3)) + phi, psi, omega = torch.unbind(D,-1) + + if return_angles: + return phi, psi, omega + + # Lift angle representations to the circle + D_features = torch.cat((torch.cos(D), torch.sin(D)), 2) + return D_features + + +class GVPGraphEmbedding(GVPInputFeaturizer): + + def __init__(self, args): + super().__init__() + self.top_k_neighbors = args.top_k_neighbors + self.num_positional_embeddings = 16 + self.remove_edges_without_coords = True + node_input_dim = (7, 3) + edge_input_dim = (34, 1) + node_hidden_dim = (args.node_hidden_dim_scalar, + args.node_hidden_dim_vector) + edge_hidden_dim = (args.edge_hidden_dim_scalar, + args.edge_hidden_dim_vector) + self.embed_node = nn.Sequential( + GVP(node_input_dim, node_hidden_dim, activations=(None, None)), + LayerNorm(node_hidden_dim, eps=1e-4) + ) + self.embed_edge = nn.Sequential( + GVP(edge_input_dim, edge_hidden_dim, activations=(None, None)), + LayerNorm(edge_hidden_dim, eps=1e-4) + ) + self.embed_confidence = nn.Linear(16, args.node_hidden_dim_scalar) + + def forward(self, coords, coord_mask, padding_mask, confidence): + with torch.no_grad(): + node_features = self.get_node_features(coords, coord_mask) + edge_features, edge_index = self.get_edge_features( + coords, coord_mask, padding_mask) + node_embeddings_scalar, node_embeddings_vector = self.embed_node(node_features) + edge_embeddings = self.embed_edge(edge_features) + + rbf_rep = rbf(confidence, 0., 1.) + node_embeddings = ( + node_embeddings_scalar + self.embed_confidence(rbf_rep), + node_embeddings_vector + ) + + node_embeddings, edge_embeddings, edge_index = flatten_graph( + node_embeddings, edge_embeddings, edge_index) + return node_embeddings, edge_embeddings, edge_index + + def get_edge_features(self, coords, coord_mask, padding_mask): + X_ca = coords[:, :, 1] + # Get distances to the top k neighbors + E_dist, E_idx, E_coord_mask, E_residue_mask = GVPInputFeaturizer._dist( + X_ca, coord_mask, padding_mask, self.top_k_neighbors) + # Flatten the graph to be batch size 1 for torch_geometric package + dest = E_idx + B, L, k = E_idx.shape[:3] + src = torch.arange(L, device=E_idx.device).view([1, L, 1]).expand(B, L, k) + # After flattening, [2, B, E] + edge_index = torch.stack([src, dest], dim=0).flatten(2, 3) + # After flattening, [B, E] + E_dist = E_dist.flatten(1, 2) + E_coord_mask = E_coord_mask.flatten(1, 2).unsqueeze(-1) + E_residue_mask = E_residue_mask.flatten(1, 2) + # Calculate relative positional embeddings and distance RBF + pos_embeddings = GVPInputFeaturizer._positional_embeddings( + edge_index, + num_positional_embeddings=self.num_positional_embeddings, + ) + D_rbf = rbf(E_dist, 0., 20.) + # Calculate relative orientation + X_src = X_ca.unsqueeze(2).expand(-1, -1, k, -1).flatten(1, 2) + X_dest = torch.gather( + X_ca, + 1, + edge_index[1, :, :].unsqueeze(-1).expand([B, L*k, 3]) + ) + coord_mask_src = coord_mask.unsqueeze(2).expand(-1, -1, k).flatten(1, 2) + coord_mask_dest = torch.gather( + coord_mask, + 1, + edge_index[1, :, :].expand([B, L*k]) + ) + E_vectors = X_src - X_dest + # For the ones without coordinates, substitute in the average vector + E_vector_mean = torch.sum(E_vectors * E_coord_mask, dim=1, + keepdims=True) / torch.sum(E_coord_mask, dim=1, keepdims=True) + E_vectors = E_vectors * E_coord_mask + E_vector_mean * ~(E_coord_mask) + # Normalize and remove nans + edge_s = torch.cat([D_rbf, pos_embeddings], dim=-1) + edge_v = normalize(E_vectors).unsqueeze(-2) + edge_s, edge_v = map(nan_to_num, (edge_s, edge_v)) + # Also add indications of whether the coordinates are present + edge_s = torch.cat([ + edge_s, + (~coord_mask_src).float().unsqueeze(-1), + (~coord_mask_dest).float().unsqueeze(-1), + ], dim=-1) + edge_index[:, ~E_residue_mask] = -1 + if self.remove_edges_without_coords: + edge_index[:, ~E_coord_mask.squeeze(-1)] = -1 + return (edge_s, edge_v), edge_index.transpose(0, 1) diff --git a/esm/source/esm/inverse_folding/gvp_encoder.py b/esm/source/esm/inverse_folding/gvp_encoder.py new file mode 100644 index 0000000000000000000000000000000000000000..a565201090624b71c272c9e23b58feb7f1cca30d --- /dev/null +++ b/esm/source/esm/inverse_folding/gvp_encoder.py @@ -0,0 +1,56 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from argparse import Namespace + +import torch +import torch.nn as nn +import torch.nn.functional as F + +from .features import GVPGraphEmbedding +from .gvp_modules import GVPConvLayer, LayerNorm +from .gvp_utils import unflatten_graph + + + +class GVPEncoder(nn.Module): + + def __init__(self, args): + super().__init__() + self.args = args + self.embed_graph = GVPGraphEmbedding(args) + + node_hidden_dim = (args.node_hidden_dim_scalar, + args.node_hidden_dim_vector) + edge_hidden_dim = (args.edge_hidden_dim_scalar, + args.edge_hidden_dim_vector) + + conv_activations = (F.relu, torch.sigmoid) + self.encoder_layers = nn.ModuleList( + GVPConvLayer( + node_hidden_dim, + edge_hidden_dim, + drop_rate=args.dropout, + vector_gate=True, + attention_heads=0, + n_message=3, + conv_activations=conv_activations, + n_edge_gvps=0, + eps=1e-4, + layernorm=True, + ) + for i in range(args.num_encoder_layers) + ) + + def forward(self, coords, coord_mask, padding_mask, confidence): + node_embeddings, edge_embeddings, edge_index = self.embed_graph( + coords, coord_mask, padding_mask, confidence) + + for i, layer in enumerate(self.encoder_layers): + node_embeddings, edge_embeddings = layer(node_embeddings, + edge_index, edge_embeddings) + + node_embeddings = unflatten_graph(node_embeddings, coords.shape[0]) + return node_embeddings diff --git a/esm/source/esm/inverse_folding/gvp_modules.py b/esm/source/esm/inverse_folding/gvp_modules.py new file mode 100644 index 0000000000000000000000000000000000000000..c60cbd3b0aa6b0536eeadb797997bf3f8c541c36 --- /dev/null +++ b/esm/source/esm/inverse_folding/gvp_modules.py @@ -0,0 +1,475 @@ +# Contents of this file are from the open source code for +# +# Jing, B., Eismann, S., Suriana, P., Townshend, R. J. L., & Dror, R. (2020). +# Learning from Protein Structure with Geometric Vector Perceptrons. In +# International Conference on Learning Representations. +# +# MIT License +# +# Copyright (c) 2020 Bowen Jing, Stephan Eismann, Patricia Suriana, Raphael Townshend, Ron Dror +# +# Permission is hereby granted, free of charge, to any person obtaining a copy +# of this software and associated documentation files (the "Software"), to deal +# in the Software without restriction, including without limitation the rights +# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +# copies of the Software, and to permit persons to whom the Software is +# furnished to do so, subject to the following conditions: +# +# The above copyright notice and this permission notice shall be included in all +# copies or substantial portions of the Software. +# +# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +# AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +# OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE +# SOFTWARE. + +import typing as T +import torch +from torch import nn +import torch.nn.functional as F +from torch_geometric.nn import MessagePassing + +def tuple_size(tp): + return tuple([0 if a is None else a.size() for a in tp]) + +def tuple_sum(tp1, tp2): + s1, v1 = tp1 + s2, v2 = tp2 + if v2 is None and v2 is None: + return (s1 + s2, None) + return (s1 + s2, v1 + v2) + +def tuple_cat(*args, dim=-1): + ''' + Concatenates any number of tuples (s, V) elementwise. + + :param dim: dimension along which to concatenate when viewed + as the `dim` index for the scalar-channel tensors. + This means that `dim=-1` will be applied as + `dim=-2` for the vector-channel tensors. + ''' + dim %= len(args[0][0].shape) + s_args, v_args = list(zip(*args)) + return torch.cat(s_args, dim=dim), torch.cat(v_args, dim=dim) + +def tuple_index(x, idx): + ''' + Indexes into a tuple (s, V) along the first dimension. + + :param idx: any object which can be used to index into a `torch.Tensor` + ''' + return x[0][idx], x[1][idx] + +def randn(n, dims, device="cpu"): + ''' + Returns random tuples (s, V) drawn elementwise from a normal distribution. + + :param n: number of data points + :param dims: tuple of dimensions (n_scalar, n_vector) + + :return: (s, V) with s.shape = (n, n_scalar) and + V.shape = (n, n_vector, 3) + ''' + return torch.randn(n, dims[0], device=device), \ + torch.randn(n, dims[1], 3, device=device) + +def _norm_no_nan(x, axis=-1, keepdims=False, eps=1e-8, sqrt=True): + ''' + L2 norm of tensor clamped above a minimum value `eps`. + + :param sqrt: if `False`, returns the square of the L2 norm + ''' + # clamp is slow + # out = torch.clamp(torch.sum(torch.square(x), axis, keepdims), min=eps) + out = torch.sum(torch.square(x), axis, keepdims) + eps + return torch.sqrt(out) if sqrt else out + +def _split(x, nv): + ''' + Splits a merged representation of (s, V) back into a tuple. + Should be used only with `_merge(s, V)` and only if the tuple + representation cannot be used. + + :param x: the `torch.Tensor` returned from `_merge` + :param nv: the number of vector channels in the input to `_merge` + ''' + v = torch.reshape(x[..., -3*nv:], x.shape[:-1] + (nv, 3)) + s = x[..., :-3*nv] + return s, v + +def _merge(s, v): + ''' + Merges a tuple (s, V) into a single `torch.Tensor`, where the + vector channels are flattened and appended to the scalar channels. + Should be used only if the tuple representation cannot be used. + Use `_split(x, nv)` to reverse. + ''' + v = torch.reshape(v, v.shape[:-2] + (3*v.shape[-2],)) + return torch.cat([s, v], -1) + +class GVP(nn.Module): + ''' + Geometric Vector Perceptron. See manuscript and README.md + for more details. + + :param in_dims: tuple (n_scalar, n_vector) + :param out_dims: tuple (n_scalar, n_vector) + :param h_dim: intermediate number of vector channels, optional + :param activations: tuple of functions (scalar_act, vector_act) + :param tuple_io: whether to keep accepting tuple inputs and outputs when vi + or vo = 0 + ''' + def __init__(self, in_dims, out_dims, h_dim=None, vector_gate=False, + activations=(F.relu, torch.sigmoid), tuple_io=True, + eps=1e-8): + super(GVP, self).__init__() + self.si, self.vi = in_dims + self.so, self.vo = out_dims + self.tuple_io = tuple_io + if self.vi: + self.h_dim = h_dim or max(self.vi, self.vo) + self.wh = nn.Linear(self.vi, self.h_dim, bias=False) + self.ws = nn.Linear(self.h_dim + self.si, self.so) + if self.vo: + self.wv = nn.Linear(self.h_dim, self.vo, bias=False) + if vector_gate: + self.wg = nn.Linear(self.so, self.vo) + else: + self.ws = nn.Linear(self.si, self.so) + + self.vector_gate = vector_gate + self.scalar_act, self.vector_act = activations + self.eps = eps + + def forward(self, x): + ''' + :param x: tuple (s, V) of `torch.Tensor`, + or (if vectors_in is 0), a single `torch.Tensor` + :return: tuple (s, V) of `torch.Tensor`, + or (if vectors_out is 0), a single `torch.Tensor` + ''' + if self.vi: + s, v = x + v = torch.transpose(v, -1, -2) + vh = self.wh(v) + vn = _norm_no_nan(vh, axis=-2, eps=self.eps) + s = self.ws(torch.cat([s, vn], -1)) + if self.scalar_act: + s = self.scalar_act(s) + if self.vo: + v = self.wv(vh) + v = torch.transpose(v, -1, -2) + if self.vector_gate: + g = self.wg(s).unsqueeze(-1) + else: + g = _norm_no_nan(v, axis=-1, keepdims=True, eps=self.eps) + if self.vector_act: + g = self.vector_act(g) + v = v * g + else: + if self.tuple_io: + assert x[1] is None + x = x[0] + s = self.ws(x) + if self.scalar_act: + s = self.scalar_act(s) + if self.vo: + v = torch.zeros(list(s.shape)[:-1] + [self.vo, 3], + device=s.device) + + if self.vo: + return (s, v) + elif self.tuple_io: + return (s, None) + else: + return s + + +class _VDropout(nn.Module): + ''' + Vector channel dropout where the elements of each + vector channel are dropped together. + ''' + def __init__(self, drop_rate): + super(_VDropout, self).__init__() + self.drop_rate = drop_rate + + def forward(self, x): + ''' + :param x: `torch.Tensor` corresponding to vector channels + ''' + if x is None: + return None + device = x.device + if not self.training: + return x + mask = torch.bernoulli( + (1 - self.drop_rate) * torch.ones(x.shape[:-1], device=device) + ).unsqueeze(-1) + x = mask * x / (1 - self.drop_rate) + return x + +class Dropout(nn.Module): + ''' + Combined dropout for tuples (s, V). + Takes tuples (s, V) as input and as output. + ''' + def __init__(self, drop_rate): + super(Dropout, self).__init__() + self.sdropout = nn.Dropout(drop_rate) + self.vdropout = _VDropout(drop_rate) + + def forward(self, x): + ''' + :param x: tuple (s, V) of `torch.Tensor`, + or single `torch.Tensor` + (will be assumed to be scalar channels) + ''' + if type(x) is torch.Tensor: + return self.sdropout(x) + s, v = x + return self.sdropout(s), self.vdropout(v) + +class LayerNorm(nn.Module): + ''' + Combined LayerNorm for tuples (s, V). + Takes tuples (s, V) as input and as output. + ''' + def __init__(self, dims, tuple_io=True, eps=1e-8): + super(LayerNorm, self).__init__() + self.tuple_io = tuple_io + self.s, self.v = dims + self.scalar_norm = nn.LayerNorm(self.s) + self.eps = eps + + def forward(self, x): + ''' + :param x: tuple (s, V) of `torch.Tensor`, + or single `torch.Tensor` + (will be assumed to be scalar channels) + ''' + if not self.v: + if self.tuple_io: + return self.scalar_norm(x[0]), None + return self.scalar_norm(x) + s, v = x + vn = _norm_no_nan(v, axis=-1, keepdims=True, sqrt=False, eps=self.eps) + nonzero_mask = (vn > 2 * self.eps) + vn = torch.sum(vn * nonzero_mask, dim=-2, keepdim=True + ) / (self.eps + torch.sum(nonzero_mask, dim=-2, keepdim=True)) + vn = torch.sqrt(vn + self.eps) + v = nonzero_mask * (v / vn) + return self.scalar_norm(s), v + +class GVPConv(MessagePassing): + ''' + Graph convolution / message passing with Geometric Vector Perceptrons. + Takes in a graph with node and edge embeddings, + and returns new node embeddings. + + This does NOT do residual updates and pointwise feedforward layers + ---see `GVPConvLayer`. + + :param in_dims: input node embedding dimensions (n_scalar, n_vector) + :param out_dims: output node embedding dimensions (n_scalar, n_vector) + :param edge_dims: input edge embedding dimensions (n_scalar, n_vector) + :param n_layers: number of GVPs in the message function + :param module_list: preconstructed message function, overrides n_layers + :param aggr: should be "add" if some incoming edges are masked, as in + a masked autoregressive decoder architecture + ''' + def __init__(self, in_dims, out_dims, edge_dims, n_layers=3, + vector_gate=False, module_list=None, aggr="mean", eps=1e-8, + activations=(F.relu, torch.sigmoid)): + super(GVPConv, self).__init__(aggr=aggr) + self.eps = eps + self.si, self.vi = in_dims + self.so, self.vo = out_dims + self.se, self.ve = edge_dims + + module_list = module_list or [] + if not module_list: + if n_layers == 1: + module_list.append( + GVP((2*self.si + self.se, 2*self.vi + self.ve), + (self.so, self.vo), activations=(None, None))) + else: + module_list.append( + GVP((2*self.si + self.se, 2*self.vi + self.ve), out_dims, + vector_gate=vector_gate, activations=activations) + ) + for i in range(n_layers - 2): + module_list.append(GVP(out_dims, out_dims, + vector_gate=vector_gate)) + module_list.append(GVP(out_dims, out_dims, + activations=(None, None))) + self.message_func = nn.Sequential(*module_list) + + def forward(self, x, edge_index, edge_attr): + ''' + :param x: tuple (s, V) of `torch.Tensor` + :param edge_index: array of shape [2, n_edges] + :param edge_attr: tuple (s, V) of `torch.Tensor` + ''' + x_s, x_v = x + message = self.propagate(edge_index, + s=x_s, v=x_v.reshape(x_v.shape[0], 3*x_v.shape[1]), + edge_attr=edge_attr) + return _split(message, self.vo) + + def message(self, s_i, v_i, s_j, v_j, edge_attr): + v_j = v_j.view(v_j.shape[0], v_j.shape[1]//3, 3) + v_i = v_i.view(v_i.shape[0], v_i.shape[1]//3, 3) + message = tuple_cat((s_j, v_j), edge_attr, (s_i, v_i)) + message = self.message_func(message) + return _merge(*message) + + +class GVPConvLayer(nn.Module): + ''' + Full graph convolution / message passing layer with + Geometric Vector Perceptrons. Residually updates node embeddings with + aggregated incoming messages, applies a pointwise feedforward + network to node embeddings, and returns updated node embeddings. + + To only compute the aggregated messages, see `GVPConv`. + + :param node_dims: node embedding dimensions (n_scalar, n_vector) + :param edge_dims: input edge embedding dimensions (n_scalar, n_vector) + :param n_message: number of GVPs to use in message function + :param n_feedforward: number of GVPs to use in feedforward function + :param drop_rate: drop probability in all dropout layers + :param autoregressive: if `True`, this `GVPConvLayer` will be used + with a different set of input node embeddings for messages + where src >= dst + ''' + def __init__(self, node_dims, edge_dims, vector_gate=False, + n_message=3, n_feedforward=2, drop_rate=.1, + autoregressive=False, attention_heads=0, + conv_activations=(F.relu, torch.sigmoid), + n_edge_gvps=0, layernorm=True, eps=1e-8): + + super(GVPConvLayer, self).__init__() + if attention_heads == 0: + self.conv = GVPConv( + node_dims, node_dims, edge_dims, n_layers=n_message, + vector_gate=vector_gate, + aggr="add" if autoregressive else "mean", + activations=conv_activations, + eps=eps, + ) + else: + raise NotImplementedError + if layernorm: + self.norm = nn.ModuleList([LayerNorm(node_dims, eps=eps) for _ in range(2)]) + else: + self.norm = nn.ModuleList([nn.Identity() for _ in range(2)]) + self.dropout = nn.ModuleList([Dropout(drop_rate) for _ in range(2)]) + + ff_func = [] + if n_feedforward == 1: + ff_func.append(GVP(node_dims, node_dims, activations=(None, None))) + else: + hid_dims = 4*node_dims[0], 2*node_dims[1] + ff_func.append(GVP(node_dims, hid_dims, vector_gate=vector_gate)) + for i in range(n_feedforward-2): + ff_func.append(GVP(hid_dims, hid_dims, vector_gate=vector_gate)) + ff_func.append(GVP(hid_dims, node_dims, activations=(None, None))) + self.ff_func = nn.Sequential(*ff_func) + + self.edge_message_func = None + if n_edge_gvps > 0: + si, vi = node_dims + se, ve = edge_dims + module_list = [ + GVP((2*si + se, 2*vi + ve), edge_dims, vector_gate=vector_gate) + ] + for i in range(n_edge_gvps - 2): + module_list.append(GVP(edge_dims, edge_dims, + vector_gate=vector_gate)) + if n_edge_gvps > 1: + module_list.append(GVP(edge_dims, edge_dims, + activations=(None, None))) + self.edge_message_func = nn.Sequential(*module_list) + if layernorm: + self.edge_norm = LayerNorm(edge_dims, eps=eps) + else: + self.edge_norm = nn.Identity() + self.edge_dropout = Dropout(drop_rate) + + def forward(self, x, edge_index, edge_attr, + autoregressive_x=None, node_mask=None): + ''' + :param x: tuple (s, V) of `torch.Tensor` + :param edge_index: array of shape [2, n_edges] + :param edge_attr: tuple (s, V) of `torch.Tensor` + :param autoregressive_x: tuple (s, V) of `torch.Tensor`. + If not `None`, will be used as srcqq node embeddings + for forming messages where src >= dst. The corrent node + embeddings `x` will still be the base of the update and the + pointwise feedforward. + :param node_mask: array of type `bool` to index into the first + dim of node embeddings (s, V). If not `None`, only + these nodes will be updated. + ''' + if self.edge_message_func: + src, dst = edge_index + if autoregressive_x is None: + x_src = x[0][src], x[1][src] + else: + mask = (src < dst).unsqueeze(-1) + x_src = ( + torch.where(mask, x[0][src], autoregressive_x[0][src]), + torch.where(mask.unsqueeze(-1), x[1][src], + autoregressive_x[1][src]) + ) + x_dst = x[0][dst], x[1][dst] + x_edge = ( + torch.cat([x_src[0], edge_attr[0], x_dst[0]], dim=-1), + torch.cat([x_src[1], edge_attr[1], x_dst[1]], dim=-2) + ) + edge_attr_dh = self.edge_message_func(x_edge) + edge_attr = self.edge_norm(tuple_sum(edge_attr, + self.edge_dropout(edge_attr_dh))) + + if autoregressive_x is not None: + # Guarding this import here to remove the dependency on torch_scatter, since this isn't used + # in ESM-IF1 + from torch_scatter import scatter_add + src, dst = edge_index + mask = src < dst + edge_index_forward = edge_index[:, mask] + edge_index_backward = edge_index[:, ~mask] + edge_attr_forward = tuple_index(edge_attr, mask) + edge_attr_backward = tuple_index(edge_attr, ~mask) + + dh = tuple_sum( + self.conv(x, edge_index_forward, edge_attr_forward), + self.conv(autoregressive_x, edge_index_backward, edge_attr_backward) + ) + + count = scatter_add(torch.ones_like(dst), dst, + dim_size=dh[0].size(0)).clamp(min=1).unsqueeze(-1) + + dh = dh[0] / count, dh[1] / count.unsqueeze(-1) + + else: + dh = self.conv(x, edge_index, edge_attr) + + if node_mask is not None: + x_ = x + x, dh = tuple_index(x, node_mask), tuple_index(dh, node_mask) + + x = self.norm[0](tuple_sum(x, self.dropout[0](dh))) + + dh = self.ff_func(x) + x = self.norm[1](tuple_sum(x, self.dropout[1](dh))) + + if node_mask is not None: + x_[0][node_mask], x_[1][node_mask] = x[0], x[1] + x = x_ + + return x, edge_attr diff --git a/esm/source/esm/inverse_folding/gvp_transformer.py b/esm/source/esm/inverse_folding/gvp_transformer.py new file mode 100644 index 0000000000000000000000000000000000000000..fabd22ffb6caee05b8cee21d057ae0fa7eec1263 --- /dev/null +++ b/esm/source/esm/inverse_folding/gvp_transformer.py @@ -0,0 +1,140 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import argparse +from typing import Any, Dict, List, Optional, Tuple, NamedTuple +import torch +from torch import nn +from torch import Tensor +import torch.nn.functional as F +from scipy.spatial import transform + +from esm.data import Alphabet + +from .features import DihedralFeatures +from .gvp_encoder import GVPEncoder +from .gvp_utils import unflatten_graph +from .gvp_transformer_encoder import GVPTransformerEncoder +from .transformer_decoder import TransformerDecoder +from .util import rotate, CoordBatchConverter + + +class GVPTransformerModel(nn.Module): + """ + GVP-Transformer inverse folding model. + + Architecture: Geometric GVP-GNN as initial layers, followed by + sequence-to-sequence Transformer encoder and decoder. + """ + + def __init__(self, args, alphabet): + super().__init__() + encoder_embed_tokens = self.build_embedding( + args, alphabet, args.encoder_embed_dim, + ) + decoder_embed_tokens = self.build_embedding( + args, alphabet, args.decoder_embed_dim, + ) + encoder = self.build_encoder(args, alphabet, encoder_embed_tokens) + decoder = self.build_decoder(args, alphabet, decoder_embed_tokens) + self.args = args + self.encoder = encoder + self.decoder = decoder + + @classmethod + def build_encoder(cls, args, src_dict, embed_tokens): + encoder = GVPTransformerEncoder(args, src_dict, embed_tokens) + return encoder + + @classmethod + def build_decoder(cls, args, tgt_dict, embed_tokens): + decoder = TransformerDecoder( + args, + tgt_dict, + embed_tokens, + ) + return decoder + + @classmethod + def build_embedding(cls, args, dictionary, embed_dim): + num_embeddings = len(dictionary) + padding_idx = dictionary.padding_idx + emb = nn.Embedding(num_embeddings, embed_dim, padding_idx) + nn.init.normal_(emb.weight, mean=0, std=embed_dim ** -0.5) + nn.init.constant_(emb.weight[padding_idx], 0) + return emb + + def forward( + self, + coords, + padding_mask, + confidence, + prev_output_tokens, + return_all_hiddens: bool = False, + features_only: bool = False, + ): + encoder_out = self.encoder(coords, padding_mask, confidence, + return_all_hiddens=return_all_hiddens) + logits, extra = self.decoder( + prev_output_tokens, + encoder_out=encoder_out, + features_only=features_only, + return_all_hiddens=return_all_hiddens, + ) + return logits, extra + + def sample(self, coords, partial_seq=None, temperature=1.0, confidence=None, device=None): + """ + Samples sequences based on multinomial sampling (no beam search). + + Args: + coords: L x 3 x 3 list representing one backbone + partial_seq: Optional, partial sequence with mask tokens if part of + the sequence is known + temperature: sampling temperature, use low temperature for higher + sequence recovery and high temperature for higher diversity + confidence: optional length L list of confidence scores for coordinates + """ + L = len(coords) + # Convert to batch format + batch_converter = CoordBatchConverter(self.decoder.dictionary) + batch_coords, confidence, _, _, padding_mask = ( + batch_converter([(coords, confidence, None)], device=device) + ) + + # Start with prepend token + mask_idx = self.decoder.dictionary.get_idx('') + sampled_tokens = torch.full((1, 1+L), mask_idx, dtype=int) + sampled_tokens[0, 0] = self.decoder.dictionary.get_idx('') + if partial_seq is not None: + for i, c in enumerate(partial_seq): + sampled_tokens[0, i+1] = self.decoder.dictionary.get_idx(c) + + # Save incremental states for faster sampling + incremental_state = dict() + + # Run encoder only once + encoder_out = self.encoder(batch_coords, padding_mask, confidence) + + # Make sure all tensors are on the same device if a GPU is present + if device: + sampled_tokens = sampled_tokens.to(device) + + # Decode one token at a time + for i in range(1, L+1): + logits, _ = self.decoder( + sampled_tokens[:, :i], + encoder_out, + incremental_state=incremental_state, + ) + logits = logits[0].transpose(0, 1) + logits /= temperature + probs = F.softmax(logits, dim=-1) + if sampled_tokens[0, i] == mask_idx: + sampled_tokens[:, i] = torch.multinomial(probs, 1).squeeze(-1) + sampled_seq = sampled_tokens[0, 1:] + + # Convert back to string via lookup + return ''.join([self.decoder.dictionary.get_tok(a) for a in sampled_seq]) diff --git a/esm/source/esm/inverse_folding/gvp_transformer_encoder.py b/esm/source/esm/inverse_folding/gvp_transformer_encoder.py new file mode 100644 index 0000000000000000000000000000000000000000..b61334739476f5d6a1b8c64e6dfa98254a70b285 --- /dev/null +++ b/esm/source/esm/inverse_folding/gvp_transformer_encoder.py @@ -0,0 +1,184 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# Contents of this file were adapted from the open source fairseq repository. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import argparse +import math +from typing import Dict, List, Optional + +import torch +import torch.nn as nn +from torch import Tensor + +from esm.modules import SinusoidalPositionalEmbedding +from .features import GVPInputFeaturizer, DihedralFeatures +from .gvp_encoder import GVPEncoder +from .transformer_layer import TransformerEncoderLayer +from .util import nan_to_num, get_rotation_frames, rotate, rbf + + +class GVPTransformerEncoder(nn.Module): + """ + Transformer encoder consisting of *args.encoder.layers* layers. Each layer + is a :class:`TransformerEncoderLayer`. + + Args: + args (argparse.Namespace): parsed command-line arguments + dictionary (~fairseq.data.Dictionary): encoding dictionary + embed_tokens (torch.nn.Embedding): input embedding + """ + + def __init__(self, args, dictionary, embed_tokens): + super().__init__() + self.args = args + self.dictionary = dictionary + + self.dropout_module = nn.Dropout(args.dropout) + + embed_dim = embed_tokens.embedding_dim + self.padding_idx = embed_tokens.padding_idx + + self.embed_tokens = embed_tokens + self.embed_scale = math.sqrt(embed_dim) + self.embed_positions = SinusoidalPositionalEmbedding( + embed_dim, + self.padding_idx, + ) + self.embed_gvp_input_features = nn.Linear(15, embed_dim) + self.embed_confidence = nn.Linear(16, embed_dim) + self.embed_dihedrals = DihedralFeatures(embed_dim) + + gvp_args = argparse.Namespace() + for k, v in vars(args).items(): + if k.startswith("gvp_"): + setattr(gvp_args, k[4:], v) + self.gvp_encoder = GVPEncoder(gvp_args) + gvp_out_dim = gvp_args.node_hidden_dim_scalar + (3 * + gvp_args.node_hidden_dim_vector) + self.embed_gvp_output = nn.Linear(gvp_out_dim, embed_dim) + + self.layers = nn.ModuleList([]) + self.layers.extend( + [self.build_encoder_layer(args) for i in range(args.encoder_layers)] + ) + self.num_layers = len(self.layers) + self.layer_norm = nn.LayerNorm(embed_dim) + + def build_encoder_layer(self, args): + return TransformerEncoderLayer(args) + + def forward_embedding(self, coords, padding_mask, confidence): + """ + Args: + coords: N, CA, C backbone coordinates in shape length x 3 (atoms) x 3 + padding_mask: boolean Tensor (true for padding) of shape length + confidence: confidence scores between 0 and 1 of shape length + """ + components = dict() + coord_mask = torch.all(torch.all(torch.isfinite(coords), dim=-1), dim=-1) + coords = nan_to_num(coords) + mask_tokens = ( + padding_mask * self.dictionary.padding_idx + + ~padding_mask * self.dictionary.get_idx("") + ) + components["tokens"] = self.embed_tokens(mask_tokens) * self.embed_scale + components["diherals"] = self.embed_dihedrals(coords) + + # GVP encoder + gvp_out_scalars, gvp_out_vectors = self.gvp_encoder(coords, + coord_mask, padding_mask, confidence) + R = get_rotation_frames(coords) + # Rotate to local rotation frame for rotation-invariance + gvp_out_features = torch.cat([ + gvp_out_scalars, + rotate(gvp_out_vectors, R.transpose(-2, -1)).flatten(-2, -1), + ], dim=-1) + components["gvp_out"] = self.embed_gvp_output(gvp_out_features) + + components["confidence"] = self.embed_confidence( + rbf(confidence, 0., 1.)) + + # In addition to GVP encoder outputs, also directly embed GVP input node + # features to the Transformer + scalar_features, vector_features = GVPInputFeaturizer.get_node_features( + coords, coord_mask, with_coord_mask=False) + features = torch.cat([ + scalar_features, + rotate(vector_features, R.transpose(-2, -1)).flatten(-2, -1), + ], dim=-1) + components["gvp_input_features"] = self.embed_gvp_input_features(features) + + embed = sum(components.values()) + # for k, v in components.items(): + # print(k, torch.mean(v, dim=(0,1)), torch.std(v, dim=(0,1))) + + x = embed + x = x + self.embed_positions(mask_tokens) + x = self.dropout_module(x) + return x, components + + def forward( + self, + coords, + encoder_padding_mask, + confidence, + return_all_hiddens: bool = False, + ): + """ + Args: + coords (Tensor): backbone coordinates + shape batch_size x num_residues x num_atoms (3 for N, CA, C) x 3 + encoder_padding_mask (ByteTensor): the positions of + padding elements of shape `(batch_size x num_residues)` + confidence (Tensor): the confidence score of shape (batch_size x + num_residues). The value is between 0. and 1. for each residue + coordinate, or -1. if no coordinate is given + return_all_hiddens (bool, optional): also return all of the + intermediate hidden states (default: False). + + Returns: + dict: + - **encoder_out** (Tensor): the last encoder layer's output of + shape `(num_residues, batch_size, embed_dim)` + - **encoder_padding_mask** (ByteTensor): the positions of + padding elements of shape `(batch_size, num_residues)` + - **encoder_embedding** (Tensor): the (scaled) embedding lookup + of shape `(batch_size, num_residues, embed_dim)` + - **encoder_states** (List[Tensor]): all intermediate + hidden states of shape `(num_residues, batch_size, embed_dim)`. + Only populated if *return_all_hiddens* is True. + """ + x, encoder_embedding = self.forward_embedding(coords, + encoder_padding_mask, confidence) + # account for padding while computing the representation + x = x * (1 - encoder_padding_mask.unsqueeze(-1).type_as(x)) + + # B x T x C -> T x B x C + x = x.transpose(0, 1) + + encoder_states = [] + + if return_all_hiddens: + encoder_states.append(x) + + # encoder layers + for layer in self.layers: + x = layer( + x, encoder_padding_mask=encoder_padding_mask + ) + if return_all_hiddens: + assert encoder_states is not None + encoder_states.append(x) + + if self.layer_norm is not None: + x = self.layer_norm(x) + + return { + "encoder_out": [x], # T x B x C + "encoder_padding_mask": [encoder_padding_mask], # B x T + "encoder_embedding": [encoder_embedding], # dictionary + "encoder_states": encoder_states, # List[T x B x C] + } diff --git a/esm/source/esm/inverse_folding/gvp_utils.py b/esm/source/esm/inverse_folding/gvp_utils.py new file mode 100644 index 0000000000000000000000000000000000000000..fc0617fff0913f0f8b0ecace8e1debd334c00299 --- /dev/null +++ b/esm/source/esm/inverse_folding/gvp_utils.py @@ -0,0 +1,68 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import torch + + +def flatten_graph(node_embeddings, edge_embeddings, edge_index): + """ + Flattens the graph into a batch size one (with disconnected subgraphs for + each example) to be compatible with pytorch-geometric package. + Args: + node_embeddings: node embeddings in tuple form (scalar, vector) + - scalar: shape batch size x nodes x node_embed_dim + - vector: shape batch size x nodes x node_embed_dim x 3 + edge_embeddings: edge embeddings of in tuple form (scalar, vector) + - scalar: shape batch size x edges x edge_embed_dim + - vector: shape batch size x edges x edge_embed_dim x 3 + edge_index: shape batch_size x 2 (source node and target node) x edges + Returns: + node_embeddings: node embeddings in tuple form (scalar, vector) + - scalar: shape batch total_nodes x node_embed_dim + - vector: shape batch total_nodes x node_embed_dim x 3 + edge_embeddings: edge embeddings of in tuple form (scalar, vector) + - scalar: shape batch total_edges x edge_embed_dim + - vector: shape batch total_edges x edge_embed_dim x 3 + edge_index: shape 2 x total_edges + """ + x_s, x_v = node_embeddings + e_s, e_v = edge_embeddings + batch_size, N = x_s.shape[0], x_s.shape[1] + node_embeddings = (torch.flatten(x_s, 0, 1), torch.flatten(x_v, 0, 1)) + edge_embeddings = (torch.flatten(e_s, 0, 1), torch.flatten(e_v, 0, 1)) + + edge_mask = torch.any(edge_index != -1, dim=1) + # Re-number the nodes by adding batch_idx * N to each batch + edge_index = edge_index + (torch.arange(batch_size, device=edge_index.device) * + N).unsqueeze(-1).unsqueeze(-1) + edge_index = edge_index.permute(1, 0, 2).flatten(1, 2) + edge_mask = edge_mask.flatten() + edge_index = edge_index[:, edge_mask] + edge_embeddings = ( + edge_embeddings[0][edge_mask, :], + edge_embeddings[1][edge_mask, :] + ) + return node_embeddings, edge_embeddings, edge_index + + +def unflatten_graph(node_embeddings, batch_size): + """ + Unflattens node embeddings. + Args: + node_embeddings: node embeddings in tuple form (scalar, vector) + - scalar: shape batch total_nodes x node_embed_dim + - vector: shape batch total_nodes x node_embed_dim x 3 + batch_size: int + Returns: + node_embeddings: node embeddings in tuple form (scalar, vector) + - scalar: shape batch size x nodes x node_embed_dim + - vector: shape batch size x nodes x node_embed_dim x 3 + """ + x_s, x_v = node_embeddings + x_s = x_s.reshape(batch_size, -1, x_s.shape[1]) + x_v = x_v.reshape(batch_size, -1, x_v.shape[1], x_v.shape[2]) + return (x_s, x_v) + + diff --git a/esm/source/esm/inverse_folding/multichain_util.py b/esm/source/esm/inverse_folding/multichain_util.py new file mode 100644 index 0000000000000000000000000000000000000000..40c4b7b520c36ca64adfdc19096762d4050c7f05 --- /dev/null +++ b/esm/source/esm/inverse_folding/multichain_util.py @@ -0,0 +1,152 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import biotite.structure +import numpy as np +import torch +from typing import Sequence, Tuple, List + +from esm.inverse_folding.util import ( + load_structure, + extract_coords_from_structure, + load_coords, + get_sequence_loss, + get_encoder_output, +) + + +def extract_coords_from_complex(structure: biotite.structure.AtomArray): + """ + Args: + structure: biotite AtomArray + Returns: + Tuple (coords_list, seq_list) + - coords: Dictionary mapping chain ids to L x 3 x 3 array for N, CA, C + coordinates representing the backbone of each chain + - seqs: Dictionary mapping chain ids to native sequences of each chain + """ + coords = {} + seqs = {} + all_chains = biotite.structure.get_chains(structure) + for chain_id in all_chains: + chain = structure[structure.chain_id == chain_id] + coords[chain_id], seqs[chain_id] = extract_coords_from_structure(chain) + return coords, seqs + + +def load_complex_coords(fpath, chains): + """ + Args: + fpath: filepath to either pdb or cif file + chains: the chain ids (the order matters for autoregressive model) + Returns: + Tuple (coords_list, seq_list) + - coords: Dictionary mapping chain ids to L x 3 x 3 array for N, CA, C + coordinates representing the backbone of each chain + - seqs: Dictionary mapping chain ids to native sequences of each chain + """ + structure = load_structure(fpath, chains) + return extract_coords_from_complex(structure) + + +def _concatenate_coords(coords, target_chain_id, padding_length=10): + """ + Args: + coords: Dictionary mapping chain ids to L x 3 x 3 array for N, CA, C + coordinates representing the backbone of each chain + target_chain_id: The chain id to sample sequences for + padding_length: Length of padding between concatenated chains + Returns: + Tuple (coords, seq) + - coords is an L x 3 x 3 array for N, CA, C coordinates, a + concatenation of the chains with padding in between + - seq is the extracted sequence, with padding tokens inserted + between the concatenated chains + """ + pad_coords = np.full((padding_length, 3, 3), np.nan, dtype=np.float32) + # For best performance, put the target chain first in concatenation. + coords_list = [coords[target_chain_id]] + for chain_id in coords: + if chain_id == target_chain_id: + continue + coords_list.append(pad_coords) + coords_list.append(coords[chain_id]) + coords_concatenated = np.concatenate(coords_list, axis=0) + return coords_concatenated + + +def sample_sequence_in_complex(model, coords, target_chain_id, temperature=1., + padding_length=10): + """ + Samples sequence for one chain in a complex. + Args: + model: An instance of the GVPTransformer model + coords: Dictionary mapping chain ids to L x 3 x 3 array for N, CA, C + coordinates representing the backbone of each chain + target_chain_id: The chain id to sample sequences for + padding_length: padding length in between chains + Returns: + Sampled sequence for the target chain + """ + target_chain_len = coords[target_chain_id].shape[0] + all_coords = _concatenate_coords(coords, target_chain_id) + device = next(model.parameters()).device + + # Supply padding tokens for other chains to avoid unused sampling for speed + padding_pattern = [''] * all_coords.shape[0] + for i in range(target_chain_len): + padding_pattern[i] = '' + sampled = model.sample(all_coords, partial_seq=padding_pattern, + temperature=temperature, device=device) + sampled = sampled[:target_chain_len] + return sampled + + +def score_sequence_in_complex(model, alphabet, coords, target_chain_id, + target_seq, padding_length=10): + """ + Scores sequence for one chain in a complex. + Args: + model: An instance of the GVPTransformer model + alphabet: Alphabet for the model + coords: Dictionary mapping chain ids to L x 3 x 3 array for N, CA, C + coordinates representing the backbone of each chain + target_chain_id: The chain id to sample sequences for + target_seq: Target sequence for the target chain for scoring. + padding_length: padding length in between chains + Returns: + Tuple (ll_fullseq, ll_withcoord) + - ll_fullseq: Average log-likelihood over the full target chain + - ll_withcoord: Average log-likelihood in target chain excluding those + residues without coordinates + """ + all_coords = _concatenate_coords(coords, target_chain_id) + + loss, target_padding_mask = get_sequence_loss(model, alphabet, all_coords, + target_seq) + ll_fullseq = -np.sum(loss * ~target_padding_mask) / np.sum( + ~target_padding_mask) + + # Also calculate average when excluding masked portions + coord_mask = np.all(np.isfinite(coords[target_chain_id]), axis=(-1, -2)) + ll_withcoord = -np.sum(loss * coord_mask) / np.sum(coord_mask) + return ll_fullseq, ll_withcoord + + +def get_encoder_output_for_complex(model, alphabet, coords, target_chain_id): + """ + Args: + model: An instance of the GVPTransformer model + alphabet: Alphabet for the model + coords: Dictionary mapping chain ids to L x 3 x 3 array for N, CA, C + coordinates representing the backbone of each chain + target_chain_id: The chain id to sample sequences for + Returns: + Dictionary mapping chain id to encoder output for each chain + """ + all_coords = _concatenate_coords(coords, target_chain_id) + all_rep = get_encoder_output(model, alphabet, all_coords) + target_chain_len = coords[target_chain_id].shape[0] + return all_rep[:target_chain_len] diff --git a/esm/source/esm/inverse_folding/transformer_decoder.py b/esm/source/esm/inverse_folding/transformer_decoder.py new file mode 100644 index 0000000000000000000000000000000000000000..59ec6f357711a45408d0fa611de7eb3bf81de7f5 --- /dev/null +++ b/esm/source/esm/inverse_folding/transformer_decoder.py @@ -0,0 +1,228 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# Contents of this file were adapted from the open source fairseq repository. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import math +from typing import Any, Dict, List, Optional + +import torch +import torch.nn as nn +from torch import Tensor + +from esm.modules import SinusoidalPositionalEmbedding +from .transformer_layer import TransformerDecoderLayer + + +def fill_with_neg_inf(t): + """FP16-compatible function that fills a tensor with -inf.""" + return t.float().fill_(float("-inf")).type_as(t) + + +class TransformerDecoder(nn.Module): + """ + Transformer decoder consisting of *args.decoder.layers* layers. Each layer + is a :class:`TransformerDecoderLayer`. + + Args: + args (argparse.Namespace): parsed command-line arguments + dictionary (~fairseq.data.Dictionary): decoding dictionary + embed_tokens (torch.nn.Embedding): output embedding + no_encoder_attn (bool, optional): whether to attend to encoder outputs + (default: False). + """ + + def __init__( + self, + args, + dictionary, + embed_tokens, + ): + super().__init__() + self.args = args + self.dictionary = dictionary + self._future_mask = torch.empty(0) + + self.dropout_module = nn.Dropout(args.dropout) + + input_embed_dim = embed_tokens.embedding_dim + embed_dim = args.decoder_embed_dim + self.embed_dim = embed_dim + + self.padding_idx = embed_tokens.padding_idx + + self.embed_tokens = embed_tokens + self.embed_scale = math.sqrt(embed_dim) + + self.project_in_dim = ( + nn.Linear(input_embed_dim, embed_dim, bias=False) + if embed_dim != input_embed_dim + else None + ) + self.embed_positions = SinusoidalPositionalEmbedding( + embed_dim, + self.padding_idx, + ) + + self.layers = nn.ModuleList([]) + self.layers.extend( + [ + self.build_decoder_layer(args) + for _ in range(args.decoder_layers) + ] + ) + self.num_layers = len(self.layers) + self.layer_norm = nn.LayerNorm(embed_dim) + + self.build_output_projection(args, dictionary) + + def build_output_projection(self, args, dictionary): + self.output_projection = nn.Linear( + args.decoder_embed_dim, len(dictionary), bias=False + ) + nn.init.normal_( + self.output_projection.weight, mean=0, std=args.decoder_embed_dim ** -0.5 + ) + + def build_decoder_layer(self, args): + return TransformerDecoderLayer(args) + + def forward( + self, + prev_output_tokens, + encoder_out: Optional[Dict[str, List[Tensor]]] = None, + incremental_state: Optional[Dict[str, Dict[str, Optional[Tensor]]]] = None, + features_only: bool = False, + return_all_hiddens: bool = False, + ): + """ + Args: + prev_output_tokens (LongTensor): previous decoder outputs of shape + `(batch, tgt_len)`, for teacher forcing + encoder_out (optional): output from the encoder, used for + encoder-side attention, should be of size T x B x C + incremental_state (dict): dictionary used for storing state during + :ref:`Incremental decoding` + features_only (bool, optional): only return features without + applying output layer (default: False). + + Returns: + tuple: + - the decoder's output of shape `(batch, tgt_len, vocab)` + - a dictionary with any model-specific outputs + """ + + x, extra = self.extract_features( + prev_output_tokens, + encoder_out=encoder_out, + incremental_state=incremental_state, + ) + + if not features_only: + x = self.output_layer(x) + x = x.transpose(1, 2) # B x T x C -> B x C x T + return x, extra + + def extract_features( + self, + prev_output_tokens, + encoder_out: Optional[Dict[str, List[Tensor]]], + incremental_state: Optional[Dict[str, Dict[str, Optional[Tensor]]]] = None, + ): + """ + Similar to *forward* but only return features. + + Includes several features from "Jointly Learning to Align and + Translate with Transformer Models" (Garg et al., EMNLP 2019). + + Returns: + tuple: + - the decoder's features of shape `(batch, tgt_len, embed_dim)` + - a dictionary with any model-specific outputs + """ + bs, slen = prev_output_tokens.size() + + enc: Optional[Tensor] = None + padding_mask: Optional[Tensor] = None + if encoder_out is not None and len(encoder_out["encoder_out"]) > 0: + enc = encoder_out["encoder_out"][0] + assert ( + enc.size()[1] == bs + ), f"Expected enc.shape == (t, {bs}, c) got {enc.shape}" + if encoder_out is not None and len(encoder_out["encoder_padding_mask"]) > 0: + padding_mask = encoder_out["encoder_padding_mask"][0] + + # embed positions + positions = self.embed_positions( + prev_output_tokens + ) + + if incremental_state is not None: + prev_output_tokens = prev_output_tokens[:, -1:] + positions = positions[:, -1:] + + # embed tokens and positions + x = self.embed_scale * self.embed_tokens(prev_output_tokens) + + if self.project_in_dim is not None: + x = self.project_in_dim(x) + + x += positions + + x = self.dropout_module(x) + + # B x T x C -> T x B x C + x = x.transpose(0, 1) + + self_attn_padding_mask: Optional[Tensor] = None + if prev_output_tokens.eq(self.padding_idx).any(): + self_attn_padding_mask = prev_output_tokens.eq(self.padding_idx) + + # decoder layers + attn: Optional[Tensor] = None + inner_states: List[Optional[Tensor]] = [x] + for idx, layer in enumerate(self.layers): + if incremental_state is None: + self_attn_mask = self.buffered_future_mask(x) + else: + self_attn_mask = None + + x, layer_attn, _ = layer( + x, + enc, + padding_mask, + incremental_state, + self_attn_mask=self_attn_mask, + self_attn_padding_mask=self_attn_padding_mask, + need_attn=False, + need_head_weights=False, + ) + inner_states.append(x) + + if self.layer_norm is not None: + x = self.layer_norm(x) + + # T x B x C -> B x C x T + x = x.transpose(0, 1) + + return x, {"inner_states": inner_states} + + def output_layer(self, features): + """Project features to the vocabulary size.""" + return self.output_projection(features) + + def buffered_future_mask(self, tensor): + dim = tensor.size(0) + # self._future_mask.device != tensor.device is not working in TorchScript. This is a workaround. + if ( + self._future_mask.size(0) == 0 + or (not self._future_mask.device == tensor.device) + or self._future_mask.size(0) < dim + ): + self._future_mask = torch.triu( + fill_with_neg_inf(torch.zeros([dim, dim])), 1 + ) + self._future_mask = self._future_mask.to(tensor) + return self._future_mask[:dim, :dim] diff --git a/esm/source/esm/inverse_folding/transformer_layer.py b/esm/source/esm/inverse_folding/transformer_layer.py new file mode 100644 index 0000000000000000000000000000000000000000..87830a3ede9c09117b1e565d53d7f23b7c551925 --- /dev/null +++ b/esm/source/esm/inverse_folding/transformer_layer.py @@ -0,0 +1,304 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# Contents of this file were adapted from the open source fairseq repository. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from typing import Dict, List, Optional + +import torch +import torch.nn as nn +import torch.nn.functional as F +from esm.multihead_attention import MultiheadAttention +from torch import Tensor + + +class TransformerEncoderLayer(nn.Module): + """Encoder layer block. + `layernorm -> dropout -> add residual` + + Args: + args (argparse.Namespace): parsed command-line arguments + """ + + def __init__(self, args): + super().__init__() + self.args = args + self.embed_dim = args.encoder_embed_dim + self.self_attn = self.build_self_attention(self.embed_dim, args) + self.self_attn_layer_norm = torch.nn.LayerNorm(self.embed_dim) + self.dropout_module = nn.Dropout(args.dropout) + self.activation_fn = F.relu + self.fc1 = self.build_fc1( + self.embed_dim, + args.encoder_ffn_embed_dim, + ) + self.fc2 = self.build_fc2( + args.encoder_ffn_embed_dim, + self.embed_dim, + ) + + self.final_layer_norm = nn.LayerNorm(self.embed_dim) + + def build_fc1(self, input_dim, output_dim): + return nn.Linear(input_dim, output_dim) + + def build_fc2(self, input_dim, output_dim): + return nn.Linear(input_dim, output_dim) + + def build_self_attention(self, embed_dim, args): + return MultiheadAttention( + embed_dim, + args.encoder_attention_heads, + dropout=args.attention_dropout, + self_attention=True, + ) + + def residual_connection(self, x, residual): + return residual + x + + def forward( + self, + x, + encoder_padding_mask: Optional[Tensor], + attn_mask: Optional[Tensor] = None, + ): + """ + Args: + x (Tensor): input to the layer of shape `(seq_len, batch, embed_dim)` + encoder_padding_mask (ByteTensor): binary ByteTensor of shape + `(batch, seq_len)` where padding elements are indicated by ``1``. + attn_mask (ByteTensor): binary tensor of shape `(tgt_len, src_len)`, + where `tgt_len` is the length of output and `src_len` is the + length of input, though here both are equal to `seq_len`. + `attn_mask[tgt_i, src_j] = 1` means that when calculating the + embedding for `tgt_i`, we exclude (mask out) `src_j`. This is + useful for strided self-attention. + + Returns: + encoded output of shape `(seq_len, batch, embed_dim)` + """ + # anything in original attn_mask = 1, becomes -1e8 + # anything in original attn_mask = 0, becomes 0 + # Note that we cannot use -inf here, because at some edge cases, + # the attention weight (before softmax) for some padded element in query + # will become -inf, which results in NaN in model parameters + if attn_mask is not None: + attn_mask = attn_mask.masked_fill( + attn_mask.to(torch.bool), -1e8 if x.dtype == torch.float32 else -1e4 + ) + + residual = x + x = self.self_attn_layer_norm(x) + x, _ = self.self_attn( + query=x, + key=x, + value=x, + key_padding_mask=encoder_padding_mask, + need_weights=False, + attn_mask=attn_mask, + ) + x = self.dropout_module(x) + x = self.residual_connection(x, residual) + + residual = x + x = self.final_layer_norm(x) + x = self.activation_fn(self.fc1(x)) + x = self.fc2(x) + x = self.dropout_module(x) + x = self.residual_connection(x, residual) + return x + + +class TransformerDecoderLayer(nn.Module): + """Decoder layer block. + `layernorm -> dropout -> add residual` + + Args: + args (argparse.Namespace): parsed command-line arguments + no_encoder_attn (bool, optional): whether to attend to encoder outputs + (default: False). + """ + + def __init__( + self, args, no_encoder_attn=False, add_bias_kv=False, add_zero_attn=False + ): + super().__init__() + self.embed_dim = args.decoder_embed_dim + self.dropout_module = nn.Dropout(args.dropout) + + self.self_attn = self.build_self_attention( + self.embed_dim, + args, + add_bias_kv=add_bias_kv, + add_zero_attn=add_zero_attn, + ) + self.nh = self.self_attn.num_heads + self.head_dim = self.self_attn.head_dim + + self.activation_fn = F.relu + + self.self_attn_layer_norm = nn.LayerNorm(self.embed_dim) + + if no_encoder_attn: + self.encoder_attn = None + self.encoder_attn_layer_norm = None + else: + self.encoder_attn = self.build_encoder_attention(self.embed_dim, args) + self.encoder_attn_layer_norm = nn.LayerNorm(self.embed_dim) + + self.ffn_layernorm = ( + LayerNorm(args.decoder_ffn_embed_dim) + if getattr(args, "scale_fc", False) + else None + ) + self.w_resid = ( + nn.Parameter( + torch.ones( + self.embed_dim, + ), + requires_grad=True, + ) + if getattr(args, "scale_resids", False) + else None + ) + + self.fc1 = self.build_fc1( + self.embed_dim, + args.decoder_ffn_embed_dim, + ) + self.fc2 = self.build_fc2( + args.decoder_ffn_embed_dim, + self.embed_dim, + ) + + self.final_layer_norm = nn.LayerNorm(self.embed_dim) + self.need_attn = True + + def build_fc1(self, input_dim, output_dim): + return nn.Linear(input_dim, output_dim) + + def build_fc2(self, input_dim, output_dim): + return nn.Linear(input_dim, output_dim) + + def build_self_attention( + self, embed_dim, args, add_bias_kv=False, add_zero_attn=False + ): + return MultiheadAttention( + embed_dim, + args.decoder_attention_heads, + dropout=args.attention_dropout, + add_bias_kv=add_bias_kv, + add_zero_attn=add_zero_attn, + self_attention=True, + ) + + def build_encoder_attention(self, embed_dim, args): + return MultiheadAttention( + embed_dim, + args.decoder_attention_heads, + kdim=args.encoder_embed_dim, + vdim=args.encoder_embed_dim, + dropout=args.attention_dropout, + encoder_decoder_attention=True, + ) + + def residual_connection(self, x, residual): + return residual + x + + def forward( + self, + x, + encoder_out: Optional[torch.Tensor] = None, + encoder_padding_mask: Optional[torch.Tensor] = None, + incremental_state: Optional[Dict[str, Dict[str, Optional[Tensor]]]] = None, + prev_self_attn_state: Optional[List[torch.Tensor]] = None, + prev_attn_state: Optional[List[torch.Tensor]] = None, + self_attn_mask: Optional[torch.Tensor] = None, + self_attn_padding_mask: Optional[torch.Tensor] = None, + need_attn: bool = False, + need_head_weights: bool = False, + ): + """ + Args: + x (Tensor): input to the layer of shape `(seq_len, batch, embed_dim)` + encoder_padding_mask (ByteTensor, optional): binary + ByteTensor of shape `(batch, src_len)` where padding + elements are indicated by ``1``. + need_attn (bool, optional): return attention weights + need_head_weights (bool, optional): return attention weights + for each head (default: return average over heads). + + Returns: + encoded output of shape `(seq_len, batch, embed_dim)` + """ + if need_head_weights: + need_attn = True + + residual = x + x = self.self_attn_layer_norm(x) + if prev_self_attn_state is not None: + prev_key, prev_value = prev_self_attn_state[:2] + saved_state: Dict[str, Optional[Tensor]] = { + "prev_key": prev_key, + "prev_value": prev_value, + } + if len(prev_self_attn_state) >= 3: + saved_state["prev_key_padding_mask"] = prev_self_attn_state[2] + assert incremental_state is not None + self.self_attn._set_input_buffer(incremental_state, saved_state) + _self_attn_input_buffer = self.self_attn._get_input_buffer(incremental_state) + y = x + + x, attn = self.self_attn( + query=x, + key=y, + value=y, + key_padding_mask=self_attn_padding_mask, + incremental_state=incremental_state, + need_weights=False, + attn_mask=self_attn_mask, + ) + x = self.dropout_module(x) + x = self.residual_connection(x, residual) + + if self.encoder_attn is not None and encoder_out is not None: + residual = x + x = self.encoder_attn_layer_norm(x) + if prev_attn_state is not None: + prev_key, prev_value = prev_attn_state[:2] + saved_state: Dict[str, Optional[Tensor]] = { + "prev_key": prev_key, + "prev_value": prev_value, + } + if len(prev_attn_state) >= 3: + saved_state["prev_key_padding_mask"] = prev_attn_state[2] + assert incremental_state is not None + self.encoder_attn._set_input_buffer(incremental_state, saved_state) + + x, attn = self.encoder_attn( + query=x, + key=encoder_out, + value=encoder_out, + key_padding_mask=encoder_padding_mask, + incremental_state=incremental_state, + static_kv=True, + need_weights=need_attn or (not self.training and self.need_attn), + need_head_weights=need_head_weights, + ) + x = self.dropout_module(x) + x = self.residual_connection(x, residual) + + residual = x + x = self.final_layer_norm(x) + + x = self.activation_fn(self.fc1(x)) + if self.ffn_layernorm is not None: + x = self.ffn_layernorm(x) + x = self.fc2(x) + x = self.dropout_module(x) + if self.w_resid is not None: + residual = torch.mul(self.w_resid, residual) + x = self.residual_connection(x, residual) + return x, attn, None diff --git a/esm/source/esm/inverse_folding/util.py b/esm/source/esm/inverse_folding/util.py new file mode 100644 index 0000000000000000000000000000000000000000..c8563fa63e866c11739ec0fb12b09368dfbf1f68 --- /dev/null +++ b/esm/source/esm/inverse_folding/util.py @@ -0,0 +1,330 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import json +import math + +import biotite.structure +from biotite.structure.io import pdbx, pdb +from biotite.structure.residues import get_residues +# from biotite.structure import filter_backbone # 在新版本biotite中不可用 +# 定义替代函数 +def filter_backbone(structure): + """ + Filter backbone atoms (N, CA, C, O) from structure + """ + backbone_atoms = ["N", "CA", "C", "O"] + return [atom.atom_name in backbone_atoms for atom in structure] +from biotite.structure import get_chains +from biotite.sequence import ProteinSequence +import numpy as np +from scipy.spatial import transform +from scipy.stats import special_ortho_group +import torch +import torch.nn as nn +import torch.nn.functional as F +import torch.utils.data as data +from typing import Sequence, Tuple, List + +from esm.data import BatchConverter + + +def load_structure(fpath, chain=None): + """ + Args: + fpath: filepath to either pdb or cif file + chain: the chain id or list of chain ids to load + Returns: + biotite.structure.AtomArray + """ + if fpath.endswith('cif'): + with open(fpath) as fin: + pdbxf = pdbx.PDBxFile.read(fin) + structure = pdbx.get_structure(pdbxf, model=1) + elif fpath.endswith('pdb'): + with open(fpath) as fin: + pdbf = pdb.PDBFile.read(fin) + structure = pdb.get_structure(pdbf, model=1) + bbmask = filter_backbone(structure) + structure = structure[bbmask] + all_chains = get_chains(structure) + if len(all_chains) == 0: + raise ValueError('No chains found in the input file.') + if chain is None: + chain_ids = all_chains + elif isinstance(chain, list): + chain_ids = chain + else: + chain_ids = [chain] + for chain in chain_ids: + if chain not in all_chains: + raise ValueError(f'Chain {chain} not found in input file') + chain_filter = [a.chain_id in chain_ids for a in structure] + structure = structure[chain_filter] + return structure + + +def extract_coords_from_structure(structure: biotite.structure.AtomArray): + """ + Args: + structure: An instance of biotite AtomArray + Returns: + Tuple (coords, seq) + - coords is an L x 3 x 3 array for N, CA, C coordinates + - seq is the extracted sequence + """ + coords = get_atom_coords_residuewise(["N", "CA", "C"], structure) + residue_identities = get_residues(structure)[1] + seq = ''.join([ProteinSequence.convert_letter_3to1(r) for r in residue_identities]) + return coords, seq + + +def load_coords(fpath, chain): + """ + Args: + fpath: filepath to either pdb or cif file + chain: the chain id + Returns: + Tuple (coords, seq) + - coords is an L x 3 x 3 array for N, CA, C coordinates + - seq is the extracted sequence + """ + structure = load_structure(fpath, chain) + return extract_coords_from_structure(structure) + + +def get_atom_coords_residuewise(atoms: List[str], struct: biotite.structure.AtomArray): + """ + Example for atoms argument: ["N", "CA", "C"] + """ + def filterfn(s, axis=None): + filters = np.stack([s.atom_name == name for name in atoms], axis=1) + sum = filters.sum(0) + if not np.all(sum <= np.ones(filters.shape[1])): + raise RuntimeError("structure has multiple atoms with same name") + index = filters.argmax(0) + coords = s[index].coord + coords[sum == 0] = float("nan") + return coords + + return biotite.structure.apply_residue_wise(struct, struct, filterfn) + + +def get_sequence_loss(model, alphabet, coords, seq): + device = next(model.parameters()).device + batch_converter = CoordBatchConverter(alphabet) + batch = [(coords, None, seq)] + coords, confidence, strs, tokens, padding_mask = batch_converter( + batch, device=device) + + prev_output_tokens = tokens[:, :-1].to(device) + target = tokens[:, 1:] + target_padding_mask = (target == alphabet.padding_idx) + logits, _ = model.forward(coords, padding_mask, confidence, prev_output_tokens) + loss = F.cross_entropy(logits, target, reduction='none') + loss = loss[0].cpu().detach().numpy() + target_padding_mask = target_padding_mask[0].cpu().numpy() + return loss, target_padding_mask + + +def score_sequence(model, alphabet, coords, seq): + loss, target_padding_mask = get_sequence_loss(model, alphabet, coords, seq) + ll_fullseq = -np.sum(loss * ~target_padding_mask) / np.sum(~target_padding_mask) + # Also calculate average when excluding masked portions + coord_mask = np.all(np.isfinite(coords), axis=(-1, -2)) + ll_withcoord = -np.sum(loss * coord_mask) / np.sum(coord_mask) + return ll_fullseq, ll_withcoord + + +def get_encoder_output(model, alphabet, coords): + device = next(model.parameters()).device + batch_converter = CoordBatchConverter(alphabet) + batch = [(coords, None, None)] + coords, confidence, strs, tokens, padding_mask = batch_converter( + batch, device=device) + encoder_out = model.encoder.forward(coords, padding_mask, confidence, + return_all_hiddens=False) + # remove beginning and end (bos and eos tokens) + return encoder_out['encoder_out'][0][1:-1, 0] + + +def rotate(v, R): + """ + Rotates a vector by a rotation matrix. + + Args: + v: 3D vector, tensor of shape (length x batch_size x channels x 3) + R: rotation matrix, tensor of shape (length x batch_size x 3 x 3) + + Returns: + Rotated version of v by rotation matrix R. + """ + R = R.unsqueeze(-3) + v = v.unsqueeze(-1) + return torch.sum(v * R, dim=-2) + + +def get_rotation_frames(coords): + """ + Returns a local rotation frame defined by N, CA, C positions. + + Args: + coords: coordinates, tensor of shape (batch_size x length x 3 x 3) + where the third dimension is in order of N, CA, C + + Returns: + Local relative rotation frames in shape (batch_size x length x 3 x 3) + """ + v1 = coords[:, :, 2] - coords[:, :, 1] + v2 = coords[:, :, 0] - coords[:, :, 1] + e1 = normalize(v1, dim=-1) + u2 = v2 - e1 * torch.sum(e1 * v2, dim=-1, keepdim=True) + e2 = normalize(u2, dim=-1) + e3 = torch.cross(e1, e2, dim=-1) + R = torch.stack([e1, e2, e3], dim=-2) + return R + + +def nan_to_num(ts, val=0.0): + """ + Replaces nans in tensor with a fixed value. + """ + val = torch.tensor(val, dtype=ts.dtype, device=ts.device) + return torch.where(~torch.isfinite(ts), val, ts) + + +def rbf(values, v_min, v_max, n_bins=16): + """ + Returns RBF encodings in a new dimension at the end. + """ + rbf_centers = torch.linspace(v_min, v_max, n_bins, device=values.device) + rbf_centers = rbf_centers.view([1] * len(values.shape) + [-1]) + rbf_std = (v_max - v_min) / n_bins + v_expand = torch.unsqueeze(values, -1) + z = (values.unsqueeze(-1) - rbf_centers) / rbf_std + return torch.exp(-z ** 2) + + +def norm(tensor, dim, eps=1e-8, keepdim=False): + """ + Returns L2 norm along a dimension. + """ + return torch.sqrt( + torch.sum(torch.square(tensor), dim=dim, keepdim=keepdim) + eps) + + +def normalize(tensor, dim=-1): + """ + Normalizes a tensor along a dimension after removing nans. + """ + return nan_to_num( + torch.div(tensor, norm(tensor, dim=dim, keepdim=True)) + ) + + +class CoordBatchConverter(BatchConverter): + def __call__(self, raw_batch: Sequence[Tuple[Sequence, str]], device=None): + """ + Args: + raw_batch: List of tuples (coords, confidence, seq) + In each tuple, + coords: list of floats, shape L x 3 x 3 + confidence: list of floats, shape L; or scalar float; or None + seq: string of length L + Returns: + coords: Tensor of shape batch_size x L x 3 x 3 + confidence: Tensor of shape batch_size x L + strs: list of strings + tokens: LongTensor of shape batch_size x L + padding_mask: ByteTensor of shape batch_size x L + """ + self.alphabet.cls_idx = self.alphabet.get_idx("") + batch = [] + for coords, confidence, seq in raw_batch: + if confidence is None: + confidence = 1. + if isinstance(confidence, float) or isinstance(confidence, int): + confidence = [float(confidence)] * len(coords) + if seq is None: + seq = 'X' * len(coords) + batch.append(((coords, confidence), seq)) + + coords_and_confidence, strs, tokens = super().__call__(batch) + + # pad beginning and end of each protein due to legacy reasons + coords = [ + F.pad(torch.tensor(cd), (0, 0, 0, 0, 1, 1), value=np.inf) + for cd, _ in coords_and_confidence + ] + confidence = [ + F.pad(torch.tensor(cf), (1, 1), value=-1.) + for _, cf in coords_and_confidence + ] + coords = self.collate_dense_tensors(coords, pad_v=np.nan) + confidence = self.collate_dense_tensors(confidence, pad_v=-1.) + if device is not None: + coords = coords.to(device) + confidence = confidence.to(device) + tokens = tokens.to(device) + padding_mask = torch.isnan(coords[:,:,0,0]) + coord_mask = torch.isfinite(coords.sum(-2).sum(-1)) + confidence = confidence * coord_mask + (-1.) * padding_mask + return coords, confidence, strs, tokens, padding_mask + + def from_lists(self, coords_list, confidence_list=None, seq_list=None, device=None): + """ + Args: + coords_list: list of length batch_size, each item is a list of + floats in shape L x 3 x 3 to describe a backbone + confidence_list: one of + - None, default to highest confidence + - list of length batch_size, each item is a scalar + - list of length batch_size, each item is a list of floats of + length L to describe the confidence scores for the backbone + with values between 0. and 1. + seq_list: either None or a list of strings + Returns: + coords: Tensor of shape batch_size x L x 3 x 3 + confidence: Tensor of shape batch_size x L + strs: list of strings + tokens: LongTensor of shape batch_size x L + padding_mask: ByteTensor of shape batch_size x L + """ + batch_size = len(coords_list) + if confidence_list is None: + confidence_list = [None] * batch_size + if seq_list is None: + seq_list = [None] * batch_size + raw_batch = zip(coords_list, confidence_list, seq_list) + return self.__call__(raw_batch, device) + + @staticmethod + def collate_dense_tensors(samples, pad_v): + """ + Takes a list of tensors with the following dimensions: + [(d_11, ..., d_1K), + (d_21, ..., d_2K), + ..., + (d_N1, ..., d_NK)] + and stack + pads them into a single tensor of: + (N, max_i=1,N { d_i1 }, ..., max_i=1,N {diK}) + """ + if len(samples) == 0: + return torch.Tensor() + if len(set(x.dim() for x in samples)) != 1: + raise RuntimeError( + f"Samples has varying dimensions: {[x.dim() for x in samples]}" + ) + (device,) = tuple(set(x.device for x in samples)) # assumes all on same device + max_shape = [max(lst) for lst in zip(*[x.shape for x in samples])] + result = torch.empty( + len(samples), *max_shape, dtype=samples[0].dtype, device=device + ) + result.fill_(pad_v) + for i in range(len(samples)): + result_i = result[i] + t = samples[i] + result_i[tuple(slice(0, k) for k in t.shape)] = t + return result diff --git a/esm/source/esm/model/__init__.py b/esm/source/esm/model/__init__.py new file mode 100644 index 0000000000000000000000000000000000000000..8b137891791fe96927ad78e64b0aad7bded08bdc --- /dev/null +++ b/esm/source/esm/model/__init__.py @@ -0,0 +1 @@ + diff --git a/esm/source/esm/model/esm1.py b/esm/source/esm/model/esm1.py new file mode 100644 index 0000000000000000000000000000000000000000..6a8c002143e845b56b1e94eca46f6ad2357d2c66 --- /dev/null +++ b/esm/source/esm/model/esm1.py @@ -0,0 +1,200 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import math + +import torch +import torch.nn as nn +import torch.nn.functional as F + +from ..modules import ( + TransformerLayer, + LearnedPositionalEmbedding, + SinusoidalPositionalEmbedding, + RobertaLMHead, + ESM1bLayerNorm, + ContactPredictionHead, +) + + +class ProteinBertModel(nn.Module): + @classmethod + def add_args(cls, parser): + parser.add_argument( + "--num_layers", default=36, type=int, metavar="N", help="number of layers" + ) + parser.add_argument( + "--embed_dim", default=1280, type=int, metavar="N", help="embedding dimension" + ) + parser.add_argument( + "--logit_bias", action="store_true", help="whether to apply bias to logits" + ) + parser.add_argument( + "--ffn_embed_dim", + default=5120, + type=int, + metavar="N", + help="embedding dimension for FFN", + ) + parser.add_argument( + "--attention_heads", + default=20, + type=int, + metavar="N", + help="number of attention heads", + ) + + def __init__(self, args, alphabet): + super().__init__() + self.args = args + self.alphabet_size = len(alphabet) + self.padding_idx = alphabet.padding_idx + self.mask_idx = alphabet.mask_idx + self.cls_idx = alphabet.cls_idx + self.eos_idx = alphabet.eos_idx + self.prepend_bos = alphabet.prepend_bos + self.append_eos = alphabet.append_eos + self.emb_layer_norm_before = getattr(self.args, "emb_layer_norm_before", False) + if self.args.arch == "roberta_large": + self.model_version = "ESM-1b" + self._init_submodules_esm1b() + else: + self.model_version = "ESM-1" + self._init_submodules_esm1() + + def _init_submodules_common(self): + self.embed_tokens = nn.Embedding( + self.alphabet_size, self.args.embed_dim, padding_idx=self.padding_idx + ) + self.layers = nn.ModuleList( + [ + TransformerLayer( + self.args.embed_dim, + self.args.ffn_embed_dim, + self.args.attention_heads, + add_bias_kv=(self.model_version != "ESM-1b"), + use_esm1b_layer_norm=(self.model_version == "ESM-1b"), + ) + for _ in range(self.args.layers) + ] + ) + + self.contact_head = ContactPredictionHead( + self.args.layers * self.args.attention_heads, + self.prepend_bos, + self.append_eos, + eos_idx=self.eos_idx, + ) + + def _init_submodules_esm1b(self): + self._init_submodules_common() + self.embed_scale = 1 + self.embed_positions = LearnedPositionalEmbedding( + self.args.max_positions, self.args.embed_dim, self.padding_idx + ) + self.emb_layer_norm_before = ( + ESM1bLayerNorm(self.args.embed_dim) if self.emb_layer_norm_before else None + ) + self.emb_layer_norm_after = ESM1bLayerNorm(self.args.embed_dim) + self.lm_head = RobertaLMHead( + embed_dim=self.args.embed_dim, + output_dim=self.alphabet_size, + weight=self.embed_tokens.weight, + ) + + def _init_submodules_esm1(self): + self._init_submodules_common() + self.embed_scale = math.sqrt(self.args.embed_dim) + self.embed_positions = SinusoidalPositionalEmbedding(self.args.embed_dim, self.padding_idx) + self.embed_out = nn.Parameter(torch.zeros((self.alphabet_size, self.args.embed_dim))) + self.embed_out_bias = None + if self.args.final_bias: + self.embed_out_bias = nn.Parameter(torch.zeros(self.alphabet_size)) + + def forward(self, tokens, repr_layers=[], need_head_weights=False, return_contacts=False): + if return_contacts: + need_head_weights = True + + assert tokens.ndim == 2 + padding_mask = tokens.eq(self.padding_idx) # B, T + + x = self.embed_scale * self.embed_tokens(tokens) + + if getattr(self.args, "token_dropout", False): + x.masked_fill_((tokens == self.mask_idx).unsqueeze(-1), 0.0) + # x: B x T x C + mask_ratio_train = 0.15 * 0.8 + src_lengths = (~padding_mask).sum(-1) + mask_ratio_observed = (tokens == self.mask_idx).sum(-1).float() / src_lengths + x = x * (1 - mask_ratio_train) / (1 - mask_ratio_observed)[:, None, None] + + x = x + self.embed_positions(tokens) + + if self.model_version == "ESM-1b": + if self.emb_layer_norm_before: + x = self.emb_layer_norm_before(x) + if padding_mask is not None: + x = x * (1 - padding_mask.unsqueeze(-1).type_as(x)) + + repr_layers = set(repr_layers) + hidden_representations = {} + if 0 in repr_layers: + hidden_representations[0] = x + + if need_head_weights: + attn_weights = [] + + # (B, T, E) => (T, B, E) + x = x.transpose(0, 1) + + if not padding_mask.any(): + padding_mask = None + + for layer_idx, layer in enumerate(self.layers): + x, attn = layer( + x, self_attn_padding_mask=padding_mask, need_head_weights=need_head_weights + ) + if (layer_idx + 1) in repr_layers: + hidden_representations[layer_idx + 1] = x.transpose(0, 1) + if need_head_weights: + # (H, B, T, T) => (B, H, T, T) + attn_weights.append(attn.transpose(1, 0)) + + if self.model_version == "ESM-1b": + x = self.emb_layer_norm_after(x) + x = x.transpose(0, 1) # (T, B, E) => (B, T, E) + + # last hidden representation should have layer norm applied + if (layer_idx + 1) in repr_layers: + hidden_representations[layer_idx + 1] = x + x = self.lm_head(x) + else: + x = F.linear(x, self.embed_out, bias=self.embed_out_bias) + x = x.transpose(0, 1) # (T, B, E) => (B, T, E) + + result = {"logits": x, "representations": hidden_representations} + if need_head_weights: + # attentions: B x L x H x T x T + attentions = torch.stack(attn_weights, 1) + if self.model_version == "ESM-1": + # ESM-1 models have an additional null-token for attention, which we remove + attentions = attentions[..., :-1] + if padding_mask is not None: + attention_mask = 1 - padding_mask.type_as(attentions) + attention_mask = attention_mask.unsqueeze(1) * attention_mask.unsqueeze(2) + attentions = attentions * attention_mask[:, None, None, :, :] + result["attentions"] = attentions + if return_contacts: + contacts = self.contact_head(tokens, attentions) + result["contacts"] = contacts + + return result + + def predict_contacts(self, tokens): + return self(tokens, return_contacts=True)["contacts"] + + @property + def num_layers(self): + return self.args.layers diff --git a/esm/source/esm/model/esm2.py b/esm/source/esm/model/esm2.py new file mode 100644 index 0000000000000000000000000000000000000000..4933307aaf24f51e9e42ec6ad7772c4c78456b5e --- /dev/null +++ b/esm/source/esm/model/esm2.py @@ -0,0 +1,147 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from typing import Union +import torch +import torch.nn as nn + +import esm +from esm.modules import ContactPredictionHead, ESM1bLayerNorm, RobertaLMHead, TransformerLayer + + +class ESM2(nn.Module): + def __init__( + self, + num_layers: int = 33, + embed_dim: int = 1280, + attention_heads: int = 20, + alphabet: Union[esm.data.Alphabet, str] = "ESM-1b", + token_dropout: bool = True, + ): + super().__init__() + self.num_layers = num_layers + self.embed_dim = embed_dim + self.attention_heads = attention_heads + if not isinstance(alphabet, esm.data.Alphabet): + alphabet = esm.data.Alphabet.from_architecture(alphabet) + self.alphabet = alphabet + self.alphabet_size = len(alphabet) + self.padding_idx = alphabet.padding_idx + self.mask_idx = alphabet.mask_idx + self.cls_idx = alphabet.cls_idx + self.eos_idx = alphabet.eos_idx + self.prepend_bos = alphabet.prepend_bos + self.append_eos = alphabet.append_eos + self.token_dropout = token_dropout + + self._init_submodules() + + def _init_submodules(self): + self.embed_scale = 1 + self.embed_tokens = nn.Embedding( + self.alphabet_size, + self.embed_dim, + padding_idx=self.padding_idx, + ) + + self.layers = nn.ModuleList( + [ + TransformerLayer( + self.embed_dim, + 4 * self.embed_dim, + self.attention_heads, + add_bias_kv=False, + use_esm1b_layer_norm=True, + use_rotary_embeddings=True, + ) + for _ in range(self.num_layers) + ] + ) + + self.contact_head = ContactPredictionHead( + self.num_layers * self.attention_heads, + self.prepend_bos, + self.append_eos, + eos_idx=self.eos_idx, + ) + self.emb_layer_norm_after = ESM1bLayerNorm(self.embed_dim) + + self.lm_head = RobertaLMHead( + embed_dim=self.embed_dim, + output_dim=self.alphabet_size, + weight=self.embed_tokens.weight, + ) + + def forward(self, tokens, repr_layers=[], need_head_weights=False, return_contacts=False): + if return_contacts: + need_head_weights = True + + assert tokens.ndim == 2 + padding_mask = tokens.eq(self.padding_idx) # B, T + + x = self.embed_scale * self.embed_tokens(tokens) + + if self.token_dropout: + x.masked_fill_((tokens == self.mask_idx).unsqueeze(-1), 0.0) + # x: B x T x C + mask_ratio_train = 0.15 * 0.8 + src_lengths = (~padding_mask).sum(-1) + mask_ratio_observed = (tokens == self.mask_idx).sum(-1).to(x.dtype) / src_lengths + x = x * (1 - mask_ratio_train) / (1 - mask_ratio_observed)[:, None, None] + + if padding_mask is not None: + x = x * (1 - padding_mask.unsqueeze(-1).type_as(x)) + + repr_layers = set(repr_layers) + hidden_representations = {} + if 0 in repr_layers: + hidden_representations[0] = x + + if need_head_weights: + attn_weights = [] + + # (B, T, E) => (T, B, E) + x = x.transpose(0, 1) + + if not padding_mask.any(): + padding_mask = None + + for layer_idx, layer in enumerate(self.layers): + x, attn = layer( + x, + self_attn_padding_mask=padding_mask, + need_head_weights=need_head_weights, + ) + if (layer_idx + 1) in repr_layers: + hidden_representations[layer_idx + 1] = x.transpose(0, 1) + if need_head_weights: + # (H, B, T, T) => (B, H, T, T) + attn_weights.append(attn.transpose(1, 0)) + + x = self.emb_layer_norm_after(x) + x = x.transpose(0, 1) # (T, B, E) => (B, T, E) + + # last hidden representation should have layer norm applied + if (layer_idx + 1) in repr_layers: + hidden_representations[layer_idx + 1] = x + x = self.lm_head(x) + + result = {"logits": x, "representations": hidden_representations} + if need_head_weights: + # attentions: B x L x H x T x T + attentions = torch.stack(attn_weights, 1) + if padding_mask is not None: + attention_mask = 1 - padding_mask.type_as(attentions) + attention_mask = attention_mask.unsqueeze(1) * attention_mask.unsqueeze(2) + attentions = attentions * attention_mask[:, None, None, :, :] + result["attentions"] = attentions + if return_contacts: + contacts = self.contact_head(tokens, attentions) + result["contacts"] = contacts + + return result + + def predict_contacts(self, tokens): + return self(tokens, return_contacts=True)["contacts"] diff --git a/esm/source/esm/model/msa_transformer.py b/esm/source/esm/model/msa_transformer.py new file mode 100644 index 0000000000000000000000000000000000000000..1107312c24092cb1c8a9325afd6b2a03c7523f22 --- /dev/null +++ b/esm/source/esm/model/msa_transformer.py @@ -0,0 +1,238 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import torch +import torch.nn as nn + +from ..modules import ( + AxialTransformerLayer, + LearnedPositionalEmbedding, + RobertaLMHead, + ESM1bLayerNorm, + ContactPredictionHead, +) + +from ..axial_attention import RowSelfAttention, ColumnSelfAttention + + + +class MSATransformer(nn.Module): + @classmethod + def add_args(cls, parser): + # fmt: off + parser.add_argument( + "--num_layers", + default=12, + type=int, + metavar="N", + help="number of layers" + ) + parser.add_argument( + "--embed_dim", + default=768, + type=int, + metavar="N", + help="embedding dimension" + ) + parser.add_argument( + "--logit_bias", + action="store_true", + help="whether to apply bias to logits" + ) + parser.add_argument( + "--ffn_embed_dim", + default=3072, + type=int, + metavar="N", + help="embedding dimension for FFN", + ) + parser.add_argument( + "--attention_heads", + default=12, + type=int, + metavar="N", + help="number of attention heads", + ) + parser.add_argument( + "--dropout", + default=0.1, + type=float, + help="Dropout to apply." + ) + parser.add_argument( + "--attention_dropout", + default=0.1, + type=float, + help="Dropout to apply." + ) + parser.add_argument( + "--activation_dropout", + default=0.1, + type=float, + help="Dropout to apply." + ) + parser.add_argument( + "--max_tokens_per_msa", + default=2 ** 14, + type=int, + help=( + "Used during inference to batch attention computations in a single " + "forward pass. This allows increased input sizes with less memory." + ), + ) + # fmt: on + + def __init__(self, args, alphabet): + super().__init__() + self.args = args + self.alphabet_size = len(alphabet) + self.padding_idx = alphabet.padding_idx + self.mask_idx = alphabet.mask_idx + self.cls_idx = alphabet.cls_idx + self.eos_idx = alphabet.eos_idx + self.prepend_bos = alphabet.prepend_bos + self.append_eos = alphabet.append_eos + + self.embed_tokens = nn.Embedding( + self.alphabet_size, self.args.embed_dim, padding_idx=self.padding_idx + ) + + if getattr(self.args, "embed_positions_msa", False): + emb_dim = getattr(self.args, "embed_positions_msa_dim", self.args.embed_dim) + self.msa_position_embedding = nn.Parameter( + 0.01 * torch.randn(1, 1024, 1, emb_dim), + requires_grad=True, + ) + else: + self.register_parameter("msa_position_embedding", None) + + self.dropout_module = nn.Dropout(self.args.dropout) + self.layers = nn.ModuleList( + [ + AxialTransformerLayer( + self.args.embed_dim, + self.args.ffn_embed_dim, + self.args.attention_heads, + self.args.dropout, + self.args.attention_dropout, + self.args.activation_dropout, + getattr(self.args, "max_tokens_per_msa", self.args.max_tokens), + ) + for _ in range(self.args.layers) + ] + ) + + self.contact_head = ContactPredictionHead( + self.args.layers * self.args.attention_heads, + self.prepend_bos, + self.append_eos, + eos_idx=self.eos_idx, + ) + self.embed_positions = LearnedPositionalEmbedding( + self.args.max_positions, + self.args.embed_dim, + self.padding_idx, + ) + self.emb_layer_norm_before = ESM1bLayerNorm(self.args.embed_dim) + self.emb_layer_norm_after = ESM1bLayerNorm(self.args.embed_dim) + self.lm_head = RobertaLMHead( + embed_dim=self.args.embed_dim, + output_dim=self.alphabet_size, + weight=self.embed_tokens.weight, + ) + + def forward(self, tokens, repr_layers=[], need_head_weights=False, return_contacts=False): + if return_contacts: + need_head_weights = True + + assert tokens.ndim == 3 + batch_size, num_alignments, seqlen = tokens.size() + padding_mask = tokens.eq(self.padding_idx) # B, R, C + if not padding_mask.any(): + padding_mask = None + + x = self.embed_tokens(tokens) + x += self.embed_positions(tokens.view(batch_size * num_alignments, seqlen)).view(x.size()) + if self.msa_position_embedding is not None: + if x.size(1) > 1024: + raise RuntimeError( + "Using model with MSA position embedding trained on maximum MSA " + f"depth of 1024, but received {x.size(1)} alignments." + ) + x += self.msa_position_embedding[:, :num_alignments] + + x = self.emb_layer_norm_before(x) + + x = self.dropout_module(x) + + if padding_mask is not None: + x = x * (1 - padding_mask.unsqueeze(-1).type_as(x)) + + repr_layers = set(repr_layers) + hidden_representations = {} + if 0 in repr_layers: + hidden_representations[0] = x + + if need_head_weights: + row_attn_weights = [] + col_attn_weights = [] + + # B x R x C x D -> R x C x B x D + x = x.permute(1, 2, 0, 3) + + for layer_idx, layer in enumerate(self.layers): + x = layer( + x, + self_attn_padding_mask=padding_mask, + need_head_weights=need_head_weights, + ) + if need_head_weights: + x, col_attn, row_attn = x + # H x C x B x R x R -> B x H x C x R x R + col_attn_weights.append(col_attn.permute(2, 0, 1, 3, 4)) + # H x B x C x C -> B x H x C x C + row_attn_weights.append(row_attn.permute(1, 0, 2, 3)) + if (layer_idx + 1) in repr_layers: + hidden_representations[layer_idx + 1] = x.permute(2, 0, 1, 3) + + x = self.emb_layer_norm_after(x) + x = x.permute(2, 0, 1, 3) # R x C x B x D -> B x R x C x D + + # last hidden representation should have layer norm applied + if (layer_idx + 1) in repr_layers: + hidden_representations[layer_idx + 1] = x + x = self.lm_head(x) + + result = {"logits": x, "representations": hidden_representations} + if need_head_weights: + # col_attentions: B x L x H x C x R x R + col_attentions = torch.stack(col_attn_weights, 1) + # row_attentions: B x L x H x C x C + row_attentions = torch.stack(row_attn_weights, 1) + result["col_attentions"] = col_attentions + result["row_attentions"] = row_attentions + if return_contacts: + contacts = self.contact_head(tokens, row_attentions) + result["contacts"] = contacts + + return result + + def predict_contacts(self, tokens): + return self(tokens, return_contacts=True)["contacts"] + + @property + def num_layers(self): + return self.args.layers + + def max_tokens_per_msa_(self, value: int) -> None: + """The MSA Transformer automatically batches attention computations when + gradients are disabled to allow you to pass in larger MSAs at test time than + you can fit in GPU memory. By default this occurs when more than 2^14 tokens + are passed in the input MSA. You can set this value to infinity to disable + this behavior. + """ + for module in self.modules(): + if isinstance(module, (RowSelfAttention, ColumnSelfAttention)): + module.max_tokens_per_msa = value diff --git a/esm/source/esm/modules.py b/esm/source/esm/modules.py new file mode 100644 index 0000000000000000000000000000000000000000..80297d9700ad921672b0daa3d661fc3e8f858a06 --- /dev/null +++ b/esm/source/esm/modules.py @@ -0,0 +1,418 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import math +from typing import Optional + +import torch +import torch.nn as nn +import torch.nn.functional as F + +from .multihead_attention import MultiheadAttention # noqa +from .axial_attention import ColumnSelfAttention, RowSelfAttention + + +def gelu(x): + """Implementation of the gelu activation function. + + For information: OpenAI GPT's gelu is slightly different + (and gives slightly different results): + 0.5 * x * (1 + torch.tanh(math.sqrt(2 / math.pi) * (x + 0.044715 * torch.pow(x, 3)))) + """ + return x * 0.5 * (1.0 + torch.erf(x / math.sqrt(2.0))) + + +def symmetrize(x): + "Make layer symmetric in final two dimensions, used for contact prediction." + return x + x.transpose(-1, -2) + + +def apc(x): + "Perform average product correct, used for contact prediction." + a1 = x.sum(-1, keepdims=True) + a2 = x.sum(-2, keepdims=True) + a12 = x.sum((-1, -2), keepdims=True) + + avg = a1 * a2 + avg.div_(a12) # in-place to reduce memory + normalized = x - avg + return normalized + + +class ESM1LayerNorm(nn.Module): + def __init__(self, hidden_size, eps=1e-12, affine=True): + """Construct a layernorm layer in the TF style (eps inside the sqrt).""" + super().__init__() + self.hidden_size = (hidden_size,) if isinstance(hidden_size, int) else tuple(hidden_size) + self.eps = eps + self.affine = bool(affine) + if self.affine: + self.weight = nn.Parameter(torch.ones(hidden_size)) + self.bias = nn.Parameter(torch.zeros(hidden_size)) + else: + self.weight, self.bias = None, None + + def forward(self, x): + dims = tuple(-(i + 1) for i in range(len(self.hidden_size))) + means = x.mean(dims, keepdim=True) + x_zeromean = x - means + variances = x_zeromean.pow(2).mean(dims, keepdim=True) + x = x_zeromean / torch.sqrt(variances + self.eps) + if self.affine: + x = (self.weight * x) + self.bias + return x + + +try: + from apex.normalization import FusedLayerNorm as _FusedLayerNorm + + class ESM1bLayerNorm(_FusedLayerNorm): + @torch.jit.unused + def forward(self, x): + if not x.is_cuda: + return super().forward(x) + else: + with torch.cuda.device(x.device): + return super().forward(x) + +except ImportError: + from torch.nn import LayerNorm as ESM1bLayerNorm + + +class TransformerLayer(nn.Module): + """Transformer layer block.""" + + def __init__( + self, + embed_dim, + ffn_embed_dim, + attention_heads, + add_bias_kv=True, + use_esm1b_layer_norm=False, + use_rotary_embeddings: bool = False, + ): + super().__init__() + self.embed_dim = embed_dim + self.ffn_embed_dim = ffn_embed_dim + self.attention_heads = attention_heads + self.use_rotary_embeddings = use_rotary_embeddings + self._init_submodules(add_bias_kv, use_esm1b_layer_norm) + + def _init_submodules(self, add_bias_kv, use_esm1b_layer_norm): + BertLayerNorm = ESM1bLayerNorm if use_esm1b_layer_norm else ESM1LayerNorm + + self.self_attn = MultiheadAttention( + self.embed_dim, + self.attention_heads, + add_bias_kv=add_bias_kv, + add_zero_attn=False, + use_rotary_embeddings=self.use_rotary_embeddings, + ) + self.self_attn_layer_norm = BertLayerNorm(self.embed_dim) + + self.fc1 = nn.Linear(self.embed_dim, self.ffn_embed_dim) + self.fc2 = nn.Linear(self.ffn_embed_dim, self.embed_dim) + + self.final_layer_norm = BertLayerNorm(self.embed_dim) + + def forward( + self, x, self_attn_mask=None, self_attn_padding_mask=None, need_head_weights=False + ): + residual = x + x = self.self_attn_layer_norm(x) + x, attn = self.self_attn( + query=x, + key=x, + value=x, + key_padding_mask=self_attn_padding_mask, + need_weights=True, + need_head_weights=need_head_weights, + attn_mask=self_attn_mask, + ) + x = residual + x + + residual = x + x = self.final_layer_norm(x) + x = gelu(self.fc1(x)) + x = self.fc2(x) + x = residual + x + + return x, attn + + +class AxialTransformerLayer(nn.Module): + """Implements an Axial MSA Transformer block.""" + + def __init__( + self, + embedding_dim: int = 768, + ffn_embedding_dim: int = 3072, + num_attention_heads: int = 8, + dropout: float = 0.1, + attention_dropout: float = 0.1, + activation_dropout: float = 0.1, + max_tokens_per_msa: int = 2**14, + ) -> None: + super().__init__() + + # Initialize parameters + self.embedding_dim = embedding_dim + self.dropout_prob = dropout + + row_self_attention = RowSelfAttention( + embedding_dim, + num_attention_heads, + dropout=dropout, + max_tokens_per_msa=max_tokens_per_msa, + ) + + column_self_attention = ColumnSelfAttention( + embedding_dim, + num_attention_heads, + dropout=dropout, + max_tokens_per_msa=max_tokens_per_msa, + ) + + feed_forward_layer = FeedForwardNetwork( + embedding_dim, + ffn_embedding_dim, + activation_dropout=activation_dropout, + max_tokens_per_msa=max_tokens_per_msa, + ) + + self.row_self_attention = self.build_residual(row_self_attention) + self.column_self_attention = self.build_residual(column_self_attention) + self.feed_forward_layer = self.build_residual(feed_forward_layer) + + def build_residual(self, layer: nn.Module): + return NormalizedResidualBlock( + layer, + self.embedding_dim, + self.dropout_prob, + ) + + def forward( + self, + x: torch.Tensor, + self_attn_mask: Optional[torch.Tensor] = None, + self_attn_padding_mask: Optional[torch.Tensor] = None, + need_head_weights: bool = False, + ): + """ + LayerNorm is applied either before or after the self-attention/ffn + modules similar to the original Transformer implementation. + """ + x, row_attn = self.row_self_attention( + x, + self_attn_mask=self_attn_mask, + self_attn_padding_mask=self_attn_padding_mask, + ) + x, column_attn = self.column_self_attention( + x, + self_attn_mask=self_attn_mask, + self_attn_padding_mask=self_attn_padding_mask, + ) + x = self.feed_forward_layer(x) + if need_head_weights: + return x, column_attn, row_attn + else: + return x + + +class LearnedPositionalEmbedding(nn.Embedding): + """ + This module learns positional embeddings up to a fixed maximum size. + Padding ids are ignored by either offsetting based on padding_idx + or by setting padding_idx to None and ensuring that the appropriate + position ids are passed to the forward function. + """ + + def __init__(self, num_embeddings: int, embedding_dim: int, padding_idx: int): + if padding_idx is not None: + num_embeddings_ = num_embeddings + padding_idx + 1 + else: + num_embeddings_ = num_embeddings + super().__init__(num_embeddings_, embedding_dim, padding_idx) + self.max_positions = num_embeddings + + def forward(self, input: torch.Tensor): + """Input is expected to be of size [bsz x seqlen].""" + if input.size(1) > self.max_positions: + raise ValueError( + f"Sequence length {input.size(1)} above maximum " + f" sequence length of {self.max_positions}" + ) + mask = input.ne(self.padding_idx).int() + positions = (torch.cumsum(mask, dim=1).type_as(mask) * mask).long() + self.padding_idx + return F.embedding( + positions, + self.weight, + self.padding_idx, + self.max_norm, + self.norm_type, + self.scale_grad_by_freq, + self.sparse, + ) + + +class SinusoidalPositionalEmbedding(nn.Module): + def __init__(self, embed_dim, padding_idx, learned=False): + super().__init__() + self.embed_dim = embed_dim + self.padding_idx = padding_idx + self.register_buffer("_float_tensor", torch.FloatTensor(1)) + self.weights = None + + def forward(self, x): + bsz, seq_len = x.shape + max_pos = self.padding_idx + 1 + seq_len + if self.weights is None or max_pos > self.weights.size(0): + self.weights = self.get_embedding(max_pos) + self.weights = self.weights.type_as(self._float_tensor) + + positions = self.make_positions(x) + return self.weights.index_select(0, positions.view(-1)).view(bsz, seq_len, -1).detach() + + def make_positions(self, x): + mask = x.ne(self.padding_idx) + range_buf = torch.arange(x.size(1), device=x.device).expand_as(x) + self.padding_idx + 1 + positions = range_buf.expand_as(x) + return positions * mask.long() + self.padding_idx * (1 - mask.long()) + + def get_embedding(self, num_embeddings): + half_dim = self.embed_dim // 2 + emb = math.log(10000) / (half_dim - 1) + emb = torch.exp(torch.arange(half_dim, dtype=torch.float) * -emb) + emb = torch.arange(num_embeddings, dtype=torch.float).unsqueeze(1) * emb.unsqueeze(0) + emb = torch.cat([torch.sin(emb), torch.cos(emb)], dim=1).view(num_embeddings, -1) + if self.embed_dim % 2 == 1: + # zero pad + emb = torch.cat([emb, torch.zeros(num_embeddings, 1)], dim=1) + if self.padding_idx is not None: + emb[self.padding_idx, :] = 0 + return emb + + +class RobertaLMHead(nn.Module): + """Head for masked language modeling.""" + + def __init__(self, embed_dim, output_dim, weight): + super().__init__() + self.dense = nn.Linear(embed_dim, embed_dim) + self.layer_norm = ESM1bLayerNorm(embed_dim) + self.weight = weight + self.bias = nn.Parameter(torch.zeros(output_dim)) + + def forward(self, features): + x = self.dense(features) + x = gelu(x) + x = self.layer_norm(x) + # project back to size of vocabulary with bias + x = F.linear(x, self.weight) + self.bias + return x + + +class ContactPredictionHead(nn.Module): + """Performs symmetrization, apc, and computes a logistic regression on the output features""" + + def __init__( + self, + in_features: int, + prepend_bos: bool, + append_eos: bool, + bias=True, + eos_idx: Optional[int] = None, + ): + super().__init__() + self.in_features = in_features + self.prepend_bos = prepend_bos + self.append_eos = append_eos + if append_eos and eos_idx is None: + raise ValueError("Using an alphabet with eos token, but no eos token was passed in.") + self.eos_idx = eos_idx + self.regression = nn.Linear(in_features, 1, bias) + self.activation = nn.Sigmoid() + + def forward(self, tokens, attentions): + # remove eos token attentions + if self.append_eos: + eos_mask = tokens.ne(self.eos_idx).to(attentions) + eos_mask = eos_mask.unsqueeze(1) * eos_mask.unsqueeze(2) + attentions = attentions * eos_mask[:, None, None, :, :] + attentions = attentions[..., :-1, :-1] + # remove cls token attentions + if self.prepend_bos: + attentions = attentions[..., 1:, 1:] + batch_size, layers, heads, seqlen, _ = attentions.size() + attentions = attentions.view(batch_size, layers * heads, seqlen, seqlen) + + # features: B x C x T x T + attentions = attentions.to( + self.regression.weight.device + ) # attentions always float32, may need to convert to float16 + attentions = apc(symmetrize(attentions)) + attentions = attentions.permute(0, 2, 3, 1) + return self.activation(self.regression(attentions).squeeze(3)) + + +class NormalizedResidualBlock(nn.Module): + def __init__( + self, + layer: nn.Module, + embedding_dim: int, + dropout: float = 0.1, + ): + super().__init__() + self.embedding_dim = embedding_dim + + self.layer = layer + self.dropout_module = nn.Dropout( + dropout, + ) + self.layer_norm = ESM1bLayerNorm(self.embedding_dim) + + def forward(self, x, *args, **kwargs): + residual = x + x = self.layer_norm(x) + outputs = self.layer(x, *args, **kwargs) + if isinstance(outputs, tuple): + x, *out = outputs + else: + x = outputs + out = None + + x = self.dropout_module(x) + x = residual + x + + if out is not None: + return (x,) + tuple(out) + else: + return x + + +class FeedForwardNetwork(nn.Module): + def __init__( + self, + embedding_dim: int, + ffn_embedding_dim: int, + activation_dropout: float = 0.1, + max_tokens_per_msa: int = 2**14, + ): + super().__init__() + self.embedding_dim = embedding_dim + self.ffn_embedding_dim = ffn_embedding_dim + self.max_tokens_per_msa = max_tokens_per_msa + self.activation_fn = nn.GELU() + self.activation_dropout_module = nn.Dropout( + activation_dropout, + ) + self.fc1 = nn.Linear(embedding_dim, ffn_embedding_dim) + self.fc2 = nn.Linear(ffn_embedding_dim, embedding_dim) + + def forward(self, x): + x = self.activation_fn(self.fc1(x)) + x = self.activation_dropout_module(x) + x = self.fc2(x) + return x diff --git a/esm/source/esm/multihead_attention.py b/esm/source/esm/multihead_attention.py new file mode 100644 index 0000000000000000000000000000000000000000..3eb745480c688cfa2e18077b689c475071f01be1 --- /dev/null +++ b/esm/source/esm/multihead_attention.py @@ -0,0 +1,508 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import math +from typing import Dict, Optional, Tuple + +import torch +import torch.nn.functional as F +from torch import Tensor, nn +from torch.nn import Parameter +from esm.rotary_embedding import RotaryEmbedding + +import uuid + + +def utils_softmax(x, dim: int, onnx_trace: bool = False): + if onnx_trace: + return F.softmax(x.float(), dim=dim) + else: + return F.softmax(x, dim=dim, dtype=torch.float32) + + +class FairseqIncrementalState(object): + def __init__(self, *args, **kwargs): + super().__init__(*args, **kwargs) + self.init_incremental_state() + + def init_incremental_state(self): + self._incremental_state_id = str(uuid.uuid4()) + + def _get_full_incremental_state_key(self, key: str) -> str: + return "{}.{}".format(self._incremental_state_id, key) + + def get_incremental_state( + self, + incremental_state: Optional[Dict[str, Dict[str, Optional[Tensor]]]], + key: str, + ) -> Optional[Dict[str, Optional[Tensor]]]: + """Helper for getting incremental state for an nn.Module.""" + full_key = self._get_full_incremental_state_key(key) + if incremental_state is None or full_key not in incremental_state: + return None + return incremental_state[full_key] + + def set_incremental_state( + self, + incremental_state: Optional[Dict[str, Dict[str, Optional[Tensor]]]], + key: str, + value: Dict[str, Optional[Tensor]], + ) -> Optional[Dict[str, Dict[str, Optional[Tensor]]]]: + """Helper for setting incremental state for an nn.Module.""" + if incremental_state is not None: + full_key = self._get_full_incremental_state_key(key) + incremental_state[full_key] = value + return incremental_state + + +def with_incremental_state(cls): + cls.__bases__ = (FairseqIncrementalState,) + tuple( + b for b in cls.__bases__ if b != FairseqIncrementalState + ) + return cls + + +@with_incremental_state +class MultiheadAttention(nn.Module): + """Multi-headed attention. + + See "Attention Is All You Need" for more details. + """ + + def __init__( + self, + embed_dim, + num_heads, + kdim=None, + vdim=None, + dropout=0.0, + bias=True, + add_bias_kv: bool = False, + add_zero_attn: bool = False, + self_attention: bool = False, + encoder_decoder_attention: bool = False, + use_rotary_embeddings: bool = False, + ): + super().__init__() + self.embed_dim = embed_dim + self.kdim = kdim if kdim is not None else embed_dim + self.vdim = vdim if vdim is not None else embed_dim + self.qkv_same_dim = self.kdim == embed_dim and self.vdim == embed_dim + + self.num_heads = num_heads + self.dropout = dropout + self.head_dim = embed_dim // num_heads + assert ( + self.head_dim * num_heads == self.embed_dim + ), "embed_dim must be divisible by num_heads" + self.scaling = self.head_dim**-0.5 + + self.self_attention = self_attention + self.encoder_decoder_attention = encoder_decoder_attention + + assert not self.self_attention or self.qkv_same_dim, ( + "Self-attention requires query, key and " "value to be of the same size" + ) + + self.k_proj = nn.Linear(self.kdim, embed_dim, bias=bias) + self.v_proj = nn.Linear(self.vdim, embed_dim, bias=bias) + self.q_proj = nn.Linear(embed_dim, embed_dim, bias=bias) + + self.out_proj = nn.Linear(embed_dim, embed_dim, bias=bias) + + if add_bias_kv: + self.bias_k = Parameter(torch.Tensor(1, 1, embed_dim)) + self.bias_v = Parameter(torch.Tensor(1, 1, embed_dim)) + else: + self.bias_k = self.bias_v = None + + self.add_zero_attn = add_zero_attn + + self.reset_parameters() + + self.onnx_trace = False + self.rot_emb = None + if use_rotary_embeddings: + self.rot_emb = RotaryEmbedding(dim=self.head_dim) + + self.enable_torch_version = False + if hasattr(F, "multi_head_attention_forward"): + self.enable_torch_version = True + else: + self.enable_torch_version = False + + def prepare_for_onnx_export_(self): + self.onnx_trace = True + + def reset_parameters(self): + if self.qkv_same_dim: + # Empirically observed the convergence to be much better with + # the scaled initialization + nn.init.xavier_uniform_(self.k_proj.weight, gain=1 / math.sqrt(2)) + nn.init.xavier_uniform_(self.v_proj.weight, gain=1 / math.sqrt(2)) + nn.init.xavier_uniform_(self.q_proj.weight, gain=1 / math.sqrt(2)) + else: + nn.init.xavier_uniform_(self.k_proj.weight) + nn.init.xavier_uniform_(self.v_proj.weight) + nn.init.xavier_uniform_(self.q_proj.weight) + + nn.init.xavier_uniform_(self.out_proj.weight) + if self.out_proj.bias is not None: + nn.init.constant_(self.out_proj.bias, 0.0) + if self.bias_k is not None: + nn.init.xavier_normal_(self.bias_k) + if self.bias_v is not None: + nn.init.xavier_normal_(self.bias_v) + + def forward( + self, + query, + key: Optional[Tensor], + value: Optional[Tensor], + key_padding_mask: Optional[Tensor] = None, + incremental_state: Optional[Dict[str, Dict[str, Optional[Tensor]]]] = None, + need_weights: bool = True, + static_kv: bool = False, + attn_mask: Optional[Tensor] = None, + before_softmax: bool = False, + need_head_weights: bool = False, + ) -> Tuple[Tensor, Optional[Tensor]]: + """Input shape: Time x Batch x Channel + + Args: + key_padding_mask (ByteTensor, optional): mask to exclude + keys that are pads, of shape `(batch, src_len)`, where + padding elements are indicated by 1s. + need_weights (bool, optional): return the attention weights, + averaged over heads (default: False). + attn_mask (ByteTensor, optional): typically used to + implement causal attention, where the mask prevents the + attention from looking forward in time (default: None). + before_softmax (bool, optional): return the raw attention + weights and values before the attention softmax. + need_head_weights (bool, optional): return the attention + weights for each head. Implies *need_weights*. Default: + return the average attention weights over all heads. + """ + if need_head_weights: + need_weights = True + + tgt_len, bsz, embed_dim = query.size() + assert embed_dim == self.embed_dim + assert list(query.size()) == [tgt_len, bsz, embed_dim] + + if ( + not self.rot_emb + and self.enable_torch_version + and not self.onnx_trace + and incremental_state is None + and not static_kv + # A workaround for quantization to work. Otherwise JIT compilation + # treats bias in linear module as method. + and not torch.jit.is_scripting() + and not need_head_weights + ): + assert key is not None and value is not None + return F.multi_head_attention_forward( + query, + key, + value, + self.embed_dim, + self.num_heads, + torch.empty([0]), + torch.cat((self.q_proj.bias, self.k_proj.bias, self.v_proj.bias)), + self.bias_k, + self.bias_v, + self.add_zero_attn, + self.dropout, + self.out_proj.weight, + self.out_proj.bias, + self.training, + key_padding_mask, + need_weights, + attn_mask, + use_separate_proj_weight=True, + q_proj_weight=self.q_proj.weight, + k_proj_weight=self.k_proj.weight, + v_proj_weight=self.v_proj.weight, + ) + if incremental_state is not None: + saved_state = self._get_input_buffer(incremental_state) + if saved_state is not None and "prev_key" in saved_state: + # previous time steps are cached - no need to recompute + # key and value if they are static + if static_kv: + assert self.encoder_decoder_attention and not self.self_attention + key = value = None + else: + saved_state = None + + if self.self_attention: + q = self.q_proj(query) + k = self.k_proj(query) + v = self.v_proj(query) + elif self.encoder_decoder_attention: + # encoder-decoder attention + q = self.q_proj(query) + if key is None: + assert value is None + k = v = None + else: + k = self.k_proj(key) + v = self.v_proj(key) + + else: + assert key is not None and value is not None + q = self.q_proj(query) + k = self.k_proj(key) + v = self.v_proj(value) + q *= self.scaling + + if self.bias_k is not None: + assert self.bias_v is not None + k = torch.cat([k, self.bias_k.repeat(1, bsz, 1)]) + v = torch.cat([v, self.bias_v.repeat(1, bsz, 1)]) + if attn_mask is not None: + attn_mask = torch.cat( + [attn_mask, attn_mask.new_zeros(attn_mask.size(0), 1)], dim=1 + ) + if key_padding_mask is not None: + key_padding_mask = torch.cat( + [ + key_padding_mask, + key_padding_mask.new_zeros(key_padding_mask.size(0), 1), + ], + dim=1, + ) + + q = q.contiguous().view(tgt_len, bsz * self.num_heads, self.head_dim).transpose(0, 1) + if k is not None: + k = k.contiguous().view(-1, bsz * self.num_heads, self.head_dim).transpose(0, 1) + if v is not None: + v = v.contiguous().view(-1, bsz * self.num_heads, self.head_dim).transpose(0, 1) + + if saved_state is not None: + # saved states are stored with shape (bsz, num_heads, seq_len, head_dim) + if "prev_key" in saved_state: + _prev_key = saved_state["prev_key"] + assert _prev_key is not None + prev_key = _prev_key.view(bsz * self.num_heads, -1, self.head_dim) + if static_kv: + k = prev_key + else: + assert k is not None + k = torch.cat([prev_key, k], dim=1) + if "prev_value" in saved_state: + _prev_value = saved_state["prev_value"] + assert _prev_value is not None + prev_value = _prev_value.view(bsz * self.num_heads, -1, self.head_dim) + if static_kv: + v = prev_value + else: + assert v is not None + v = torch.cat([prev_value, v], dim=1) + prev_key_padding_mask: Optional[Tensor] = None + if "prev_key_padding_mask" in saved_state: + prev_key_padding_mask = saved_state["prev_key_padding_mask"] + assert k is not None and v is not None + key_padding_mask = MultiheadAttention._append_prev_key_padding_mask( + key_padding_mask=key_padding_mask, + prev_key_padding_mask=prev_key_padding_mask, + batch_size=bsz, + src_len=k.size(1), + static_kv=static_kv, + ) + + saved_state["prev_key"] = k.view(bsz, self.num_heads, -1, self.head_dim) + saved_state["prev_value"] = v.view(bsz, self.num_heads, -1, self.head_dim) + saved_state["prev_key_padding_mask"] = key_padding_mask + # In this branch incremental_state is never None + assert incremental_state is not None + incremental_state = self._set_input_buffer(incremental_state, saved_state) + assert k is not None + src_len = k.size(1) + + # This is part of a workaround to get around fork/join parallelism + # not supporting Optional types. + if key_padding_mask is not None and key_padding_mask.dim() == 0: + key_padding_mask = None + + if key_padding_mask is not None: + assert key_padding_mask.size(0) == bsz + assert key_padding_mask.size(1) == src_len + + if self.add_zero_attn: + assert v is not None + src_len += 1 + k = torch.cat([k, k.new_zeros((k.size(0), 1) + k.size()[2:])], dim=1) + v = torch.cat([v, v.new_zeros((v.size(0), 1) + v.size()[2:])], dim=1) + if attn_mask is not None: + attn_mask = torch.cat( + [attn_mask, attn_mask.new_zeros(attn_mask.size(0), 1)], dim=1 + ) + if key_padding_mask is not None: + key_padding_mask = torch.cat( + [ + key_padding_mask, + torch.zeros(key_padding_mask.size(0), 1).type_as(key_padding_mask), + ], + dim=1, + ) + + if self.rot_emb: + q, k = self.rot_emb(q, k) + + attn_weights = torch.bmm(q, k.transpose(1, 2)) + attn_weights = MultiheadAttention.apply_sparse_mask(attn_weights, tgt_len, src_len, bsz) + + assert list(attn_weights.size()) == [bsz * self.num_heads, tgt_len, src_len] + + if attn_mask is not None: + attn_mask = attn_mask.unsqueeze(0) + if self.onnx_trace: + attn_mask = attn_mask.repeat(attn_weights.size(0), 1, 1) + attn_weights += attn_mask + + if key_padding_mask is not None: + # don't attend to padding symbols + attn_weights = attn_weights.view(bsz, self.num_heads, tgt_len, src_len) + attn_weights = attn_weights.masked_fill( + key_padding_mask.unsqueeze(1).unsqueeze(2).to(torch.bool), float("-inf") + ) + attn_weights = attn_weights.view(bsz * self.num_heads, tgt_len, src_len) + + if before_softmax: + return attn_weights, v + + attn_weights_float = utils_softmax(attn_weights, dim=-1, onnx_trace=self.onnx_trace) + attn_weights = attn_weights_float.type_as(attn_weights) + attn_probs = F.dropout( + attn_weights_float.type_as(attn_weights), + p=self.dropout, + training=self.training, + ) + assert v is not None + attn = torch.bmm(attn_probs, v) + assert list(attn.size()) == [bsz * self.num_heads, tgt_len, self.head_dim] + if self.onnx_trace and attn.size(1) == 1: + # when ONNX tracing a single decoder step (sequence length == 1) + # the transpose is a no-op copy before view, thus unnecessary + attn = attn.contiguous().view(tgt_len, bsz, embed_dim) + else: + attn = attn.transpose(0, 1).contiguous().view(tgt_len, bsz, embed_dim) + attn = self.out_proj(attn) + attn_weights: Optional[Tensor] = None + if need_weights: + attn_weights = attn_weights_float.view( + bsz, self.num_heads, tgt_len, src_len + ).type_as(attn).transpose(1, 0) + if not need_head_weights: + # average attention weights over heads + attn_weights = attn_weights.mean(dim=0) + + return attn, attn_weights + + @staticmethod + def _append_prev_key_padding_mask( + key_padding_mask: Optional[Tensor], + prev_key_padding_mask: Optional[Tensor], + batch_size: int, + src_len: int, + static_kv: bool, + ) -> Optional[Tensor]: + # saved key padding masks have shape (bsz, seq_len) + if prev_key_padding_mask is not None and static_kv: + new_key_padding_mask = prev_key_padding_mask + elif prev_key_padding_mask is not None and key_padding_mask is not None: + new_key_padding_mask = torch.cat( + [prev_key_padding_mask.float(), key_padding_mask.float()], dim=1 + ) + # During incremental decoding, as the padding token enters and + # leaves the frame, there will be a time when prev or current + # is None + elif prev_key_padding_mask is not None: + filler = torch.zeros( + (batch_size, src_len - prev_key_padding_mask.size(1)), + device=prev_key_padding_mask.device, + ) + new_key_padding_mask = torch.cat( + [prev_key_padding_mask.float(), filler.float()], dim=1 + ) + elif key_padding_mask is not None: + filler = torch.zeros( + (batch_size, src_len - key_padding_mask.size(1)), + device=key_padding_mask.device, + ) + new_key_padding_mask = torch.cat([filler.float(), key_padding_mask.float()], dim=1) + else: + new_key_padding_mask = prev_key_padding_mask + return new_key_padding_mask + + @torch.jit.export + def reorder_incremental_state( + self, incremental_state: Dict[str, Dict[str, Optional[Tensor]]], new_order: Tensor + ): + """Reorder buffered internal state (for incremental generation).""" + input_buffer = self._get_input_buffer(incremental_state) + if input_buffer is not None: + for k in input_buffer.keys(): + input_buffer_k = input_buffer[k] + if input_buffer_k is not None: + if self.encoder_decoder_attention and input_buffer_k.size(0) == new_order.size( + 0 + ): + break + input_buffer[k] = input_buffer_k.index_select(0, new_order) + incremental_state = self._set_input_buffer(incremental_state, input_buffer) + return incremental_state + + def _get_input_buffer( + self, incremental_state: Optional[Dict[str, Dict[str, Optional[Tensor]]]] + ) -> Dict[str, Optional[Tensor]]: + result = self.get_incremental_state(incremental_state, "attn_state") + if result is not None: + return result + else: + empty_result: Dict[str, Optional[Tensor]] = {} + return empty_result + + def _set_input_buffer( + self, + incremental_state: Dict[str, Dict[str, Optional[Tensor]]], + buffer: Dict[str, Optional[Tensor]], + ): + return self.set_incremental_state(incremental_state, "attn_state", buffer) + + def apply_sparse_mask(attn_weights, tgt_len: int, src_len: int, bsz: int): + return attn_weights + + def upgrade_state_dict_named(self, state_dict, name): + prefix = name + "." if name != "" else "" + items_to_add = {} + keys_to_remove = [] + for k in state_dict.keys(): + if k.endswith(prefix + "in_proj_weight"): + # in_proj_weight used to be q + k + v with same dimensions + dim = int(state_dict[k].shape[0] / 3) + items_to_add[prefix + "q_proj.weight"] = state_dict[k][:dim] + items_to_add[prefix + "k_proj.weight"] = state_dict[k][dim : 2 * dim] + items_to_add[prefix + "v_proj.weight"] = state_dict[k][2 * dim :] + + keys_to_remove.append(k) + + k_bias = prefix + "in_proj_bias" + if k_bias in state_dict.keys(): + dim = int(state_dict[k].shape[0] / 3) + items_to_add[prefix + "q_proj.bias"] = state_dict[k_bias][:dim] + items_to_add[prefix + "k_proj.bias"] = state_dict[k_bias][dim : 2 * dim] + items_to_add[prefix + "v_proj.bias"] = state_dict[k_bias][2 * dim :] + + keys_to_remove.append(prefix + "in_proj_bias") + + for k in keys_to_remove: + del state_dict[k] + + for key, value in items_to_add.items(): + state_dict[key] = value diff --git a/esm/source/esm/pretrained.py b/esm/source/esm/pretrained.py new file mode 100644 index 0000000000000000000000000000000000000000..d1941d8c14c87f3d76e9cce26fa6391b14c4f715 --- /dev/null +++ b/esm/source/esm/pretrained.py @@ -0,0 +1,552 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import re +import urllib +import warnings +from argparse import Namespace +from pathlib import Path + +import torch + +import esm +from esm.model.esm2 import ESM2 + + +def _has_regression_weights(model_name): + """Return whether we expect / require regression weights; + Right now that is all models except ESM-1v, ESM-IF, and partially trained ESM2 models""" + return not ("esm1v" in model_name or "esm_if" in model_name or "270K" in model_name or "500K" in model_name) + + +def load_model_and_alphabet(model_name): + if model_name.endswith(".pt"): # treat as filepath + return load_model_and_alphabet_local(model_name) + else: + return load_model_and_alphabet_hub(model_name) + + +def load_hub_workaround(url): + try: + data = torch.hub.load_state_dict_from_url(url, progress=False, map_location="cpu") + except RuntimeError: + # Pytorch version issue - see https://github.com/pytorch/pytorch/issues/43106 + fn = Path(url).name + data = torch.load( + f"{torch.hub.get_dir()}/checkpoints/{fn}", + map_location="cpu", + ) + except urllib.error.HTTPError as e: + raise Exception(f"Could not load {url}, check if you specified a correct model name?") + return data + + +def load_regression_hub(model_name): + url = f"https://dl.fbaipublicfiles.com/fair-esm/regression/{model_name}-contact-regression.pt" + regression_data = load_hub_workaround(url) + return regression_data + + +def _download_model_and_regression_data(model_name): + url = f"https://dl.fbaipublicfiles.com/fair-esm/models/{model_name}.pt" + model_data = load_hub_workaround(url) + if _has_regression_weights(model_name): + regression_data = load_regression_hub(model_name) + else: + regression_data = None + return model_data, regression_data + + +def load_model_and_alphabet_hub(model_name): + model_data, regression_data = _download_model_and_regression_data(model_name) + return load_model_and_alphabet_core(model_name, model_data, regression_data) + + +def load_model_and_alphabet_local(model_location): + """Load from local path. The regression weights need to be co-located""" + model_location = Path(model_location) + model_data = torch.load(str(model_location), map_location="cpu") + model_name = model_location.stem + if _has_regression_weights(model_name): + regression_location = str(model_location.with_suffix("")) + "-contact-regression.pt" + regression_data = torch.load(regression_location, map_location="cpu") + else: + regression_data = None + return load_model_and_alphabet_core(model_name, model_data, regression_data) + + +def has_emb_layer_norm_before(model_state): + """Determine whether layer norm needs to be applied before the encoder""" + return any(k.startswith("emb_layer_norm_before") for k, param in model_state.items()) + + +def _load_model_and_alphabet_core_v1(model_data): + import esm # since esm.inverse_folding is imported below, you actually have to re-import esm here + + alphabet = esm.Alphabet.from_architecture(model_data["args"].arch) + + if model_data["args"].arch == "roberta_large": + # upgrade state dict + pra = lambda s: "".join(s.split("encoder_")[1:] if "encoder" in s else s) + prs1 = lambda s: "".join(s.split("encoder.")[1:] if "encoder" in s else s) + prs2 = lambda s: "".join( + s.split("sentence_encoder.")[1:] if "sentence_encoder" in s else s + ) + model_args = {pra(arg[0]): arg[1] for arg in vars(model_data["args"]).items()} + model_state = {prs1(prs2(arg[0])): arg[1] for arg in model_data["model"].items()} + model_state["embed_tokens.weight"][alphabet.mask_idx].zero_() # For token drop + model_args["emb_layer_norm_before"] = has_emb_layer_norm_before(model_state) + model_type = esm.ProteinBertModel + + elif model_data["args"].arch == "protein_bert_base": + + # upgrade state dict + pra = lambda s: "".join(s.split("decoder_")[1:] if "decoder" in s else s) + prs = lambda s: "".join(s.split("decoder.")[1:] if "decoder" in s else s) + model_args = {pra(arg[0]): arg[1] for arg in vars(model_data["args"]).items()} + model_state = {prs(arg[0]): arg[1] for arg in model_data["model"].items()} + model_type = esm.ProteinBertModel + elif model_data["args"].arch == "msa_transformer": + + # upgrade state dict + pra = lambda s: "".join(s.split("encoder_")[1:] if "encoder" in s else s) + prs1 = lambda s: "".join(s.split("encoder.")[1:] if "encoder" in s else s) + prs2 = lambda s: "".join( + s.split("sentence_encoder.")[1:] if "sentence_encoder" in s else s + ) + prs3 = lambda s: s.replace("row", "column") if "row" in s else s.replace("column", "row") + model_args = {pra(arg[0]): arg[1] for arg in vars(model_data["args"]).items()} + model_state = {prs1(prs2(prs3(arg[0]))): arg[1] for arg in model_data["model"].items()} + if model_args.get("embed_positions_msa", False): + emb_dim = model_state["msa_position_embedding"].size(-1) + model_args["embed_positions_msa_dim"] = emb_dim # initial release, bug: emb_dim==1 + + model_type = esm.MSATransformer + + elif "invariant_gvp" in model_data["args"].arch: + import esm.inverse_folding + + model_type = esm.inverse_folding.gvp_transformer.GVPTransformerModel + model_args = vars(model_data["args"]) # convert Namespace -> dict + + def update_name(s): + # Map the module names in checkpoints trained with internal code to + # the updated module names in open source code + s = s.replace("W_v", "embed_graph.embed_node") + s = s.replace("W_e", "embed_graph.embed_edge") + s = s.replace("embed_scores.0", "embed_confidence") + s = s.replace("embed_score.", "embed_graph.embed_confidence.") + s = s.replace("seq_logits_projection.", "") + s = s.replace("embed_ingraham_features", "embed_dihedrals") + s = s.replace("embed_gvp_in_local_frame.0", "embed_gvp_output") + s = s.replace("embed_features_in_local_frame.0", "embed_gvp_input_features") + return s + + model_state = { + update_name(sname): svalue + for sname, svalue in model_data["model"].items() + if "version" not in sname + } + + else: + raise ValueError("Unknown architecture selected") + + model = model_type( + Namespace(**model_args), + alphabet, + ) + + return model, alphabet, model_state + + +def _load_model_and_alphabet_core_v2(model_data): + def upgrade_state_dict(state_dict): + """Removes prefixes 'model.encoder.sentence_encoder.' and 'model.encoder.'.""" + prefixes = ["encoder.sentence_encoder.", "encoder."] + pattern = re.compile("^" + "|".join(prefixes)) + state_dict = {pattern.sub("", name): param for name, param in state_dict.items()} + return state_dict + + cfg = model_data["cfg"]["model"] + state_dict = model_data["model"] + state_dict = upgrade_state_dict(state_dict) + alphabet = esm.data.Alphabet.from_architecture("ESM-1b") + model = ESM2( + num_layers=cfg.encoder_layers, + embed_dim=cfg.encoder_embed_dim, + attention_heads=cfg.encoder_attention_heads, + alphabet=alphabet, + token_dropout=cfg.token_dropout, + ) + return model, alphabet, state_dict + + +def load_model_and_alphabet_core(model_name, model_data, regression_data=None): + if regression_data is not None: + model_data["model"].update(regression_data["model"]) + + if model_name.startswith("esm2"): + model, alphabet, model_state = _load_model_and_alphabet_core_v2(model_data) + else: + model, alphabet, model_state = _load_model_and_alphabet_core_v1(model_data) + + expected_keys = set(model.state_dict().keys()) + found_keys = set(model_state.keys()) + + if regression_data is None: + expected_missing = {"contact_head.regression.weight", "contact_head.regression.bias"} + error_msgs = [] + missing = (expected_keys - found_keys) - expected_missing + if missing: + error_msgs.append(f"Missing key(s) in state_dict: {missing}.") + unexpected = found_keys - expected_keys + if unexpected: + error_msgs.append(f"Unexpected key(s) in state_dict: {unexpected}.") + + if error_msgs: + raise RuntimeError( + "Error(s) in loading state_dict for {}:\n\t{}".format( + model.__class__.__name__, "\n\t".join(error_msgs) + ) + ) + if expected_missing - found_keys: + warnings.warn( + "Regression weights not found, predicting contacts will not produce correct results." + ) + + model.load_state_dict(model_state, strict=regression_data is not None) + + return model, alphabet + + +def esm1_t34_670M_UR50S(): + """34 layer transformer model with 670M params, trained on Uniref50 Sparse. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm1_t34_670M_UR50S") + + +def esm1_t34_670M_UR50D(): + """34 layer transformer model with 670M params, trained on Uniref50 Dense. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm1_t34_670M_UR50D") + + +def esm1_t34_670M_UR100(): + """34 layer transformer model with 670M params, trained on Uniref100. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm1_t34_670M_UR100") + + +def esm1_t12_85M_UR50S(): + """12 layer transformer model with 85M params, trained on Uniref50 Sparse. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm1_t12_85M_UR50S") + + +def esm1_t6_43M_UR50S(): + """6 layer transformer model with 43M params, trained on Uniref50 Sparse. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm1_t6_43M_UR50S") + + +def esm1b_t33_650M_UR50S(): + """33 layer transformer model with 650M params, trained on Uniref50 Sparse. + This is our best performing model, which will be described in a future publication. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm1b_t33_650M_UR50S") + + +def esm_msa1_t12_100M_UR50S(): + warnings.warn( + "This model had a minor bug in the positional embeddings, " + "please use ESM-MSA-1b: esm.pretrained.esm_msa1b_t12_100M_UR50S()", + ) + return load_model_and_alphabet_hub("esm_msa1_t12_100M_UR50S") + + +def esm_msa1b_t12_100M_UR50S(): + return load_model_and_alphabet_hub("esm_msa1b_t12_100M_UR50S") + + +def esm1v_t33_650M_UR90S(): + """33 layer transformer model with 650M params, trained on Uniref90. + This is model 1 of a 5 model ensemble. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm1v_t33_650M_UR90S_1") + + +def esm1v_t33_650M_UR90S_1(): + """33 layer transformer model with 650M params, trained on Uniref90. + This is model 1 of a 5 model ensemble. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm1v_t33_650M_UR90S_1") + + +def esm1v_t33_650M_UR90S_2(): + """33 layer transformer model with 650M params, trained on Uniref90. + This is model 2 of a 5 model ensemble. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm1v_t33_650M_UR90S_2") + + +def esm1v_t33_650M_UR90S_3(): + """33 layer transformer model with 650M params, trained on Uniref90. + This is model 3 of a 5 model ensemble. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm1v_t33_650M_UR90S_3") + + +def esm1v_t33_650M_UR90S_4(): + """33 layer transformer model with 650M params, trained on Uniref90. + This is model 4 of a 5 model ensemble. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm1v_t33_650M_UR90S_4") + + +def esm1v_t33_650M_UR90S_5(): + """33 layer transformer model with 650M params, trained on Uniref90. + This is model 5 of a 5 model ensemble. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm1v_t33_650M_UR90S_5") + + +def esm_if1_gvp4_t16_142M_UR50(): + """Inverse folding model with 142M params, with 4 GVP-GNN layers, 8 + Transformer encoder layers, and 8 Transformer decoder layers, trained on + CATH structures and 12 million alphafold2 predicted structures from UniRef50 + sequences. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm_if1_gvp4_t16_142M_UR50") + + +def esm2_t6_8M_UR50D(): + """6 layer ESM-2 model with 8M params, trained on UniRef50. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm2_t6_8M_UR50D") + + +def esm2_t12_35M_UR50D(): + """12 layer ESM-2 model with 35M params, trained on UniRef50. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm2_t12_35M_UR50D") + + +def esm2_t30_150M_UR50D(): + """30 layer ESM-2 model with 150M params, trained on UniRef50. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm2_t30_150M_UR50D") + + +def esm2_t33_650M_UR50D(): + """33 layer ESM-2 model with 650M params, trained on UniRef50. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm2_t33_650M_UR50D") + + +def esm2_t36_3B_UR50D(): + """36 layer ESM-2 model with 3B params, trained on UniRef50. + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm2_t36_3B_UR50D") + + +def esm2_t48_15B_UR50D(): + """48 layer ESM-2 model with 15B params, trained on UniRef50. + If you have OOM while loading this model, please refer to README + on how to employ FSDP and ZeRO CPU offloading + + Returns a tuple of (Model, Alphabet). + """ + return load_model_and_alphabet_hub("esm2_t48_15B_UR50D") + + +def esmfold_v0(): + """ + ESMFold v0 model with 3B ESM-2, 48 folding blocks. + This version was used for the paper (Lin et al, 2022). It was trained + on all PDB chains until 2020-05, to ensure temporal holdout with CASP14 + and the CAMEO validation and test set reported there. + """ + import esm.esmfold.v1.pretrained + return esm.esmfold.v1.pretrained.esmfold_v0() + + +def esmfold_v1(): + """ + ESMFold v1 model using 3B ESM-2, 48 folding blocks. + ESMFold provides fast high accuracy atomic level structure prediction + directly from the individual sequence of a protein. ESMFold uses the ESM2 + protein language model to extract meaningful representations from the + protein sequence. + """ + import esm.esmfold.v1.pretrained + return esm.esmfold.v1.pretrained.esmfold_v1() + +def esmfold_structure_module_only_8M(): + """ + ESMFold baseline model using 8M ESM-2, 0 folding blocks. + ESM-2 here is trained out to 500K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + import esm.esmfold.v1.pretrained + return esm.esmfold.v1.pretrained.esmfold_structure_module_only_8M() + + +def esmfold_structure_module_only_8M_270K(): + """ + ESMFold baseline model using 8M ESM-2, 0 folding blocks. + ESM-2 here is trained out to 270K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + import esm.esmfold.v1.pretrained + return esm.esmfold.v1.pretrained.esmfold_structure_module_only_8M_270K() + + +def esmfold_structure_module_only_35M(): + """ + ESMFold baseline model using 35M ESM-2, 0 folding blocks. + ESM-2 here is trained out to 500K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + import esm.esmfold.v1.pretrained + return esm.esmfold.v1.pretrained.esmfold_structure_module_only_35M() + + +def esmfold_structure_module_only_35M_270K(): + """ + ESMFold baseline model using 35M ESM-2, 0 folding blocks. + ESM-2 here is trained out to 270K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + import esm.esmfold.v1.pretrained + return esm.esmfold.v1.pretrained.esmfold_structure_module_only_35M_270K() + + +def esmfold_structure_module_only_150M(): + """ + ESMFold baseline model using 150M ESM-2, 0 folding blocks. + ESM-2 here is trained out to 500K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + import esm.esmfold.v1.pretrained + return esm.esmfold.v1.pretrained.esmfold_structure_module_only_150M() + + +def esmfold_structure_module_only_150M_270K(): + """ + ESMFold baseline model using 150M ESM-2, 0 folding blocks. + ESM-2 here is trained out to 270K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + import esm.esmfold.v1.pretrained + return esm.esmfold.v1.pretrained.esmfold_structure_module_only_150M_270K() + + +def esmfold_structure_module_only_650M(): + """ + ESMFold baseline model using 650M ESM-2, 0 folding blocks. + ESM-2 here is trained out to 500K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + import esm.esmfold.v1.pretrained + return esm.esmfold.v1.pretrained.esmfold_structure_module_only_650M() + + +def esmfold_structure_module_only_650M_270K(): + """ + ESMFold baseline model using 650M ESM-2, 0 folding blocks. + ESM-2 here is trained out to 270K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + import esm.esmfold.v1.pretrained + return esm.esmfold.v1.pretrained.esmfold_structure_module_only_650M_270K() + + +def esmfold_structure_module_only_3B(): + """ + ESMFold baseline model using 3B ESM-2, 0 folding blocks. + ESM-2 here is trained out to 500K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + import esm.esmfold.v1.pretrained + return esm.esmfold.v1.pretrained.esmfold_structure_module_only_3B() + + +def esmfold_structure_module_only_3B_270K(): + """ + ESMFold baseline model using 3B ESM-2, 0 folding blocks. + ESM-2 here is trained out to 270K updates. + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + import esm.esmfold.v1.pretrained + return esm.esmfold.v1.pretrained.esmfold_structure_module_only_3B_270K() + + +def esmfold_structure_module_only_15B(): + """ + ESMFold baseline model using 15B ESM-2, 0 folding blocks. + ESM-2 here is trained out to 270K updates. + The 15B parameter ESM-2 was not trained out to 500K updates + This is a model designed to test the capabilities of the language model + when ablated for number of parameters in the language model. + See table S1 in (Lin et al, 2022). + """ + import esm.esmfold.v1.pretrained + return esm.esmfold.v1.pretrained.esmfold_structure_module_only_15B() diff --git a/esm/source/esm/rotary_embedding.py b/esm/source/esm/rotary_embedding.py new file mode 100644 index 0000000000000000000000000000000000000000..e773982d90d54e332d9369b5e1826832acacfc38 --- /dev/null +++ b/esm/source/esm/rotary_embedding.py @@ -0,0 +1,69 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from typing import Tuple + +import torch + + +def rotate_half(x): + x1, x2 = x.chunk(2, dim=-1) + return torch.cat((-x2, x1), dim=-1) + + +def apply_rotary_pos_emb(x, cos, sin): + cos = cos[:, : x.shape[-2], :] + sin = sin[:, : x.shape[-2], :] + + return (x * cos) + (rotate_half(x) * sin) + + +class RotaryEmbedding(torch.nn.Module): + """ + The rotary position embeddings from RoFormer_ (Su et. al). + A crucial insight from the method is that the query and keys are + transformed by rotation matrices which depend on the relative positions. + Other implementations are available in the Rotary Transformer repo_ and in + GPT-NeoX_, GPT-NeoX was an inspiration + .. _RoFormer: https://arxiv.org/abs/2104.09864 + .. _repo: https://github.com/ZhuiyiTechnology/roformer + .. _GPT-NeoX: https://github.com/EleutherAI/gpt-neox + .. warning: Please note that this embedding is not registered on purpose, as it is transformative + (it does not create the embedding dimension) and will likely be picked up (imported) on a ad-hoc basis + """ + + def __init__(self, dim: int, *_, **__): + super().__init__() + # Generate and save the inverse frequency buffer (non trainable) + inv_freq = 1.0 / (10000 ** (torch.arange(0, dim, 2).float() / dim)) + self.register_buffer("inv_freq", inv_freq) + + self._seq_len_cached = None + self._cos_cached = None + self._sin_cached = None + + def _update_cos_sin_tables(self, x, seq_dimension=1): + seq_len = x.shape[seq_dimension] + + # Reset the tables if the sequence length has changed, + # or if we're on a new device (possibly due to tracing for instance) + if seq_len != self._seq_len_cached or self._cos_cached.device != x.device: + self._seq_len_cached = seq_len + t = torch.arange(x.shape[seq_dimension], device=x.device).type_as(self.inv_freq) + freqs = torch.einsum("i,j->ij", t, self.inv_freq) + emb = torch.cat((freqs, freqs), dim=-1).to(x.device) + + self._cos_cached = emb.cos()[None, :, :] + self._sin_cached = emb.sin()[None, :, :] + + return self._cos_cached, self._sin_cached + + def forward(self, q: torch.Tensor, k: torch.Tensor) -> Tuple[torch.Tensor, torch.Tensor]: + self._cos_cached, self._sin_cached = self._update_cos_sin_tables(k, seq_dimension=-2) + + return ( + apply_rotary_pos_emb(q, self._cos_cached, self._sin_cached), + apply_rotary_pos_emb(k, self._cos_cached, self._sin_cached), + ) diff --git a/esm/source/esm/version.py b/esm/source/esm/version.py new file mode 100644 index 0000000000000000000000000000000000000000..271f36efa775e1a23929f69a3d5c4883291eabe7 --- /dev/null +++ b/esm/source/esm/version.py @@ -0,0 +1,6 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +version = "2.0.1" diff --git a/esm/source/examples/README.md b/esm/source/examples/README.md new file mode 100644 index 0000000000000000000000000000000000000000..adf01fb8e4c7cbb25164b09e6ba8a19ea3ec9318 --- /dev/null +++ b/esm/source/examples/README.md @@ -0,0 +1,11 @@ +# What's in this directory + +* The notebooks are introduced and summarized in `../README.md` +* `data/some_proteins.fasta` and its smaller version, `data/few_proteins.fasta` are a random selection of UniRef50 sequences used in the second example of `../README.md` +* `data/1a3a_1_A.a3m`, `data/1xcr_1_A.a3m`, `data/5ahw_1_A.a3m` are MSAs distributed with trRosetta, used in `contact_prediction.ipynb` +* `data/P62593.fasta` is introduced and used in `sup_variant_prediction.ipynb` +* Example MSAs genereated in the same way as the MSAs used for MSA Transformer pre-training: + - `data/UniRef50_E9K9Y4.a3m`, `data/UniRef50_UPI0003108055.a3m`, `data/UniRef50_UPI0003674933.a3m`, from the same sequences as trRosetta: + `data/hhblits_uniclust_2017_10_1a3a_1_A.a3m`, `data/hhblits_uniclust_2017_10_1xcr_1_A.a3m`, `data/hhblits_uniclust_2017_10_5ahw_1_A.a3m`. + - Generated with: `hhblits -i UniRef50_$id.fas -oa3m UniRef50_$id.a3m -n 3 -d /uniclust30_2017_10/uniclust30_2017_10`. +* `esm2_infer_fairscale_fsdp_cpu_offloading.py` shows how to load the ESM-2 15B model with Fairscale's FSDP's CPU offloading capability on a single GPU \ No newline at end of file diff --git a/esm/source/examples/contact_prediction.ipynb b/esm/source/examples/contact_prediction.ipynb new file mode 100644 index 0000000000000000000000000000000000000000..cb1a803b266d7442eb6d5806dc5b8c8393750278 --- /dev/null +++ b/esm/source/examples/contact_prediction.ipynb @@ -0,0 +1,1243 @@ +{ + "cells": [ + { + "cell_type": "markdown", + "metadata": { + "id": "U0ukYqqzateL" + }, + "source": [ + "## Setup (Colab)\n", + "\n", + "If in colab, you will need to install these dependencies, download this data, and the model weights. If you are not in colab, you may have some of these already installed, or may need to install other dependencies (e.g. pytorch).\n", + "\n", + "At the moment, every block in this section is commented out. Uncomment in order to run in colab and install/download." + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "IiB2IaU6QyF9" + }, + "source": [ + "### Install dependencies" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "I2MLDXLJQmnB", + "outputId": "55c703a5-4cb4-40fa-ccd7-0edc137db259" + }, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Collecting biopython\n", + " Downloading biopython-1.79-cp37-cp37m-manylinux_2_5_x86_64.manylinux1_x86_64.whl (2.3 MB)\n", + "\u001b[K |████████████████████████████████| 2.3 MB 5.3 MB/s \n", + "\u001b[?25hCollecting biotite\n", + " Downloading biotite-0.32.0.tar.gz (31.8 MB)\n", + "\u001b[K |████████████████████████████████| 31.8 MB 1.8 MB/s \n", + "\u001b[?25h Installing build dependencies ... \u001b[?25l\u001b[?25hdone\n", + " Getting requirements to build wheel ... \u001b[?25l\u001b[?25hdone\n", + " Preparing wheel metadata ... \u001b[?25l\u001b[?25hdone\n", + "Collecting fair-esm\n", + " Downloading fair_esm-0.4.2-py3-none-any.whl (39 kB)\n", + "Requirement already satisfied: numpy in /usr/local/lib/python3.7/dist-packages (from biopython) (1.21.5)\n", + "Requirement already satisfied: requests>=2.12 in /usr/local/lib/python3.7/dist-packages (from biotite) (2.23.0)\n", + "Requirement already satisfied: networkx>=2.0 in /usr/local/lib/python3.7/dist-packages (from biotite) (2.6.3)\n", + "Requirement already satisfied: msgpack>=0.5.6 in /usr/local/lib/python3.7/dist-packages (from biotite) (1.0.3)\n", + "Requirement already satisfied: certifi>=2017.4.17 in /usr/local/lib/python3.7/dist-packages (from requests>=2.12->biotite) (2021.10.8)\n", + "Requirement already satisfied: chardet<4,>=3.0.2 in /usr/local/lib/python3.7/dist-packages (from requests>=2.12->biotite) (3.0.4)\n", + "Requirement already satisfied: urllib3!=1.25.0,!=1.25.1,<1.26,>=1.21.1 in /usr/local/lib/python3.7/dist-packages (from requests>=2.12->biotite) (1.24.3)\n", + "Requirement already satisfied: idna<3,>=2.5 in /usr/local/lib/python3.7/dist-packages (from requests>=2.12->biotite) (2.10)\n", + "Building wheels for collected packages: biotite\n", + " Building wheel for biotite (PEP 517) ... \u001b[?25l\u001b[?25hdone\n", + " Created wheel for biotite: filename=biotite-0.32.0-cp37-cp37m-linux_x86_64.whl size=38716237 sha256=4f117bb362fb5b23d42ab3d789bb99270e8e4dbd70bfc080aafe0c3b6d183cba\n", + " Stored in directory: /root/.cache/pip/wheels/46/9e/15/da04a4aae9330b947f032301925e5a2f1f6c27f673d39293f6\n", + "Successfully built biotite\n", + "Installing collected packages: fair-esm, biotite, biopython\n", + "Successfully installed biopython-1.79 biotite-0.32.0 fair-esm-0.4.2\n", + "Reading package lists... Done\n", + "Building dependency tree \n", + "Reading state information... Done\n", + "The following additional packages will be installed:\n", + " libc-ares2\n", + "The following NEW packages will be installed:\n", + " aria2 libc-ares2\n", + "0 upgraded, 2 newly installed, 0 to remove and 39 not upgraded.\n", + "Need to get 1,274 kB of archives.\n", + "After this operation, 4,912 kB of additional disk space will be used.\n", + "Get:1 http://archive.ubuntu.com/ubuntu bionic-updates/main amd64 libc-ares2 amd64 1.14.0-1ubuntu0.1 [37.5 kB]\n", + "Get:2 http://archive.ubuntu.com/ubuntu bionic/universe amd64 aria2 amd64 1.33.1-1 [1,236 kB]\n", + "Fetched 1,274 kB in 0s (3,480 kB/s)\n", + "Selecting previously unselected package libc-ares2:amd64.\n", + "(Reading database ... 155455 files and directories currently installed.)\n", + "Preparing to unpack .../libc-ares2_1.14.0-1ubuntu0.1_amd64.deb ...\n", + "Unpacking libc-ares2:amd64 (1.14.0-1ubuntu0.1) ...\n", + "Selecting previously unselected package aria2.\n", + "Preparing to unpack .../aria2_1.33.1-1_amd64.deb ...\n", + "Unpacking aria2 (1.33.1-1) ...\n", + "Setting up libc-ares2:amd64 (1.14.0-1ubuntu0.1) ...\n", + "Setting up aria2 (1.33.1-1) ...\n", + "Processing triggers for man-db (2.8.3-2ubuntu0.1) ...\n", + "Processing triggers for libc-bin (2.27-3ubuntu1.3) ...\n", + "/sbin/ldconfig.real: /usr/local/lib/python3.7/dist-packages/ideep4py/lib/libmkldnn.so.0 is not a symbolic link\n", + "\n" + ] + } + ], + "source": [ + "# !pip install biopython biotite\n", + "# !pip install git+https://github.com/facebookresearch/esm.git\n", + "# !apt-get install aria2" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "O0_SqulVQ9Kh" + }, + "source": [ + "### Download Data" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "pp3DicGHSAI4", + "outputId": "57f0ebc0-08fe-484f-82c4-3c920c71346b" + }, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + " % Total % Received % Xferd Average Speed Time Time Time Current\n", + " Dload Upload Total Spent Left Speed\n", + "100 508k 0 508k 0 0 2689k 0 --:--:-- --:--:-- --:--:-- 2689k\n", + " % Total % Received % Xferd Average Speed Time Time Time Current\n", + " Dload Upload Total Spent Left Speed\n", + "100 1134k 0 1134k 0 0 5970k 0 --:--:-- --:--:-- --:--:-- 5970k\n", + " % Total % Received % Xferd Average Speed Time Time Time Current\n", + " Dload Upload Total Spent Left Speed\n", + "100 547k 0 547k 0 0 3143k 0 --:--:-- --:--:-- --:--:-- 3143k\n", + " % Total % Received % Xferd Average Speed Time Time Time Current\n", + " Dload Upload Total Spent Left Speed\n", + "100 147k 100 147k 0 0 924k 0 --:--:-- --:--:-- --:--:-- 924k\n", + " % Total % Received % Xferd Average Speed Time Time Time Current\n", + " Dload Upload Total Spent Left Speed\n", + "100 127k 100 127k 0 0 761k 0 --:--:-- --:--:-- --:--:-- 757k\n", + " % Total % Received % Xferd Average Speed Time Time Time Current\n", + " Dload Upload Total Spent Left Speed\n", + "100 181k 100 181k 0 0 1008k 0 --:--:-- --:--:-- --:--:-- 1008k\n" + ] + } + ], + "source": [ + "# # Download MSAs from esm example repo\n", + "# !curl -O https://raw.githubusercontent.com/facebookresearch/esm/main/examples/data/1a3a_1_A.a3m\n", + "# !curl -O https://raw.githubusercontent.com/facebookresearch/esm/main/examples/data/5ahw_1_A.a3m\n", + "# !curl -O https://raw.githubusercontent.com/facebookresearch/esm/main/examples/data/1xcr_1_A.a3m" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "Nad5sAXqREhx" + }, + "source": [ + "### Download model weights\n", + "This download code is technically unnecessary. ESM will download weights automatically. However, it's *really* slow on colab. aria2c is much faster." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "8e2GzK00RT_L", + "outputId": "277db03e-2922-4cd3-c436-44bc11e0d26f" + }, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "\n", + "04/12 20:46:44 [\u001b[1;32mNOTICE\u001b[0m] Downloading 1 item(s)\n", + "\n", + "04/12 20:46:44 [\u001b[1;32mNOTICE\u001b[0m] GID#2bb7743048f09594 - Download has already completed: /root/.cache/torch/hub/checkpoints/esm1b_t33_650M_UR50S.pt\n", + "\n", + "04/12 20:46:44 [\u001b[1;32mNOTICE\u001b[0m] Download complete: /root/.cache/torch/hub/checkpoints/esm1b_t33_650M_UR50S.pt\n", + "\n", + "Download Results:\n", + "gid |stat|avg speed |path/URI\n", + "======+====+===========+=======================================================\n", + "2bb774|\u001b[1;32mOK\u001b[0m | 0B/s|/root/.cache/torch/hub/checkpoints/esm1b_t33_650M_UR50S.pt\n", + "\n", + "Status Legend:\n", + "(OK):download completed.\n", + "\n", + "04/12 20:46:44 [\u001b[1;32mNOTICE\u001b[0m] Downloading 1 item(s)\n", + "\n", + "04/12 20:46:45 [\u001b[1;32mNOTICE\u001b[0m] GID#9acf7bb38fe44e13 - 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Needed to load aligned sequences in an MSA. \"\"\"\n", + " return sequence.translate(translation)\n", + "\n", + "def read_msa(filename: str) -> List[Tuple[str, str]]:\n", + " \"\"\" Reads the sequences from an MSA file, automatically removes insertions.\"\"\"\n", + " return [(record.description, remove_insertions(str(record.seq))) for record in SeqIO.parse(filename, \"fasta\")]" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "tV3WCbn6aXL7" + }, + "source": [ + "### Converting structures to contacts\n", + "\n", + "There are many ways to define a protein contact. Here we're using the definition of 8 angstroms between carbon beta atoms. Note that the position of the carbon beta is imputed from the position of the N, CA, and C atoms for each residue." + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "metadata": { + "id": "n4FBkOUaWuXb" + }, + "outputs": [], + "source": [ + "def extend(a, b, c, L, A, D):\n", + " \"\"\"\n", + " input: 3 coords (a,b,c), (L)ength, (A)ngle, and (D)ihedral\n", + " output: 4th coord\n", + " \"\"\"\n", + "\n", + " def normalize(x):\n", + " return x / np.linalg.norm(x, ord=2, axis=-1, keepdims=True)\n", + "\n", + " bc = normalize(b - c)\n", + " n = normalize(np.cross(b - a, bc))\n", + " m = [bc, np.cross(n, bc), n]\n", + " d = [L * np.cos(A), L * np.sin(A) * np.cos(D), -L * np.sin(A) * np.sin(D)]\n", + " return c + sum([m * d for m, d in zip(m, d)])\n", + "\n", + "\n", + "def contacts_from_pdb(\n", + " structure: bs.AtomArray,\n", + " distance_threshold: float = 8.0,\n", + " chain: Optional[str] = None,\n", + ") -> np.ndarray:\n", + " mask = ~structure.hetero\n", + " if chain is not None:\n", + " mask &= structure.chain_id == chain\n", + "\n", + " N = structure.coord[mask & (structure.atom_name == \"N\")]\n", + " CA = structure.coord[mask & (structure.atom_name == \"CA\")]\n", + " C = structure.coord[mask & (structure.atom_name == \"C\")]\n", + "\n", + " Cbeta = extend(C, N, CA, 1.522, 1.927, -2.143)\n", + " dist = squareform(pdist(Cbeta))\n", + " \n", + " contacts = dist < distance_threshold\n", + " contacts = contacts.astype(np.int64)\n", + " contacts[np.isnan(dist)] = -1\n", + " return contacts" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "mqwybh2Tn_Ou" + }, + "source": [ + "### Subsampling MSA" + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "metadata": { + "id": "dSdxag5OmOmK" + }, + "outputs": [], + "source": [ + "# Select sequences from the MSA to maximize the hamming distance\n", + "# Alternatively, can use hhfilter \n", + "def greedy_select(msa: List[Tuple[str, str]], num_seqs: int, mode: str = \"max\") -> List[Tuple[str, str]]:\n", + " assert mode in (\"max\", \"min\")\n", + " if len(msa) <= num_seqs:\n", + " return msa\n", + " \n", + " array = np.array([list(seq) for _, seq in msa], dtype=np.bytes_).view(np.uint8)\n", + "\n", + " optfunc = np.argmax if mode == \"max\" else np.argmin\n", + " all_indices = np.arange(len(msa))\n", + " indices = [0]\n", + " pairwise_distances = np.zeros((0, len(msa)))\n", + " for _ in range(num_seqs - 1):\n", + " dist = cdist(array[indices[-1:]], array, \"hamming\")\n", + " pairwise_distances = np.concatenate([pairwise_distances, dist])\n", + " shifted_distance = np.delete(pairwise_distances, indices, axis=1).mean(0)\n", + " shifted_index = optfunc(shifted_distance)\n", + " index = np.delete(all_indices, indices)[shifted_index]\n", + " indices.append(index)\n", + " indices = sorted(indices)\n", + " return [msa[idx] for idx in indices]" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "lW5thQpSn0Rp" + }, + "source": [ + "### Compute contact precisions" + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "metadata": { + "id": "c7T9xWTXeIaR" + }, + "outputs": [], + "source": [ + "def compute_precisions(\n", + " predictions: torch.Tensor,\n", + " targets: torch.Tensor,\n", + " src_lengths: Optional[torch.Tensor] = None,\n", + " minsep: int = 6,\n", + " maxsep: Optional[int] = None,\n", + " override_length: Optional[int] = None, # for casp\n", + "):\n", + " if isinstance(predictions, np.ndarray):\n", + " predictions = torch.from_numpy(predictions)\n", + " if isinstance(targets, np.ndarray):\n", + " targets = torch.from_numpy(targets)\n", + " if predictions.dim() == 2:\n", + " predictions = predictions.unsqueeze(0)\n", + " if targets.dim() == 2:\n", + " targets = targets.unsqueeze(0)\n", + " override_length = (targets[0, 0] >= 0).sum()\n", + "\n", + " # Check sizes\n", + " if predictions.size() != targets.size():\n", + " raise ValueError(\n", + " f\"Size mismatch. Received predictions of size {predictions.size()}, \"\n", + " f\"targets of size {targets.size()}\"\n", + " )\n", + " device = predictions.device\n", + "\n", + " batch_size, seqlen, _ = predictions.size()\n", + " seqlen_range = torch.arange(seqlen, device=device)\n", + "\n", + " sep = seqlen_range.unsqueeze(0) - seqlen_range.unsqueeze(1)\n", + " sep = sep.unsqueeze(0)\n", + " valid_mask = sep >= minsep\n", + " valid_mask = valid_mask & (targets >= 0) # negative targets are invalid\n", + "\n", + " if maxsep is not None:\n", + " valid_mask &= sep < maxsep\n", + "\n", + " if src_lengths is not None:\n", + " valid = seqlen_range.unsqueeze(0) < src_lengths.unsqueeze(1)\n", + " valid_mask &= valid.unsqueeze(1) & valid.unsqueeze(2)\n", + " else:\n", + " src_lengths = torch.full([batch_size], seqlen, device=device, dtype=torch.long)\n", + "\n", + " predictions = predictions.masked_fill(~valid_mask, float(\"-inf\"))\n", + "\n", + " x_ind, y_ind = np.triu_indices(seqlen, minsep)\n", + " predictions_upper = predictions[:, x_ind, y_ind]\n", + " targets_upper = targets[:, x_ind, y_ind]\n", + "\n", + " topk = seqlen if override_length is None else max(seqlen, override_length)\n", + " indices = predictions_upper.argsort(dim=-1, descending=True)[:, :topk]\n", + " topk_targets = targets_upper[torch.arange(batch_size).unsqueeze(1), indices]\n", + " if topk_targets.size(1) < topk:\n", + " topk_targets = F.pad(topk_targets, [0, topk - topk_targets.size(1)])\n", + "\n", + " cumulative_dist = topk_targets.type_as(predictions).cumsum(-1)\n", + "\n", + " gather_lengths = src_lengths.unsqueeze(1)\n", + " if override_length is not None:\n", + " gather_lengths = override_length * torch.ones_like(\n", + " gather_lengths, device=device\n", + " )\n", + "\n", + " gather_indices = (\n", + " torch.arange(0.1, 1.1, 0.1, device=device).unsqueeze(0) * gather_lengths\n", + " ).type(torch.long) - 1\n", + "\n", + " binned_cumulative_dist = cumulative_dist.gather(1, gather_indices)\n", + " binned_precisions = binned_cumulative_dist / (gather_indices + 1).type_as(\n", + " binned_cumulative_dist\n", + " )\n", + "\n", + " pl5 = binned_precisions[:, 1]\n", + " pl2 = binned_precisions[:, 4]\n", + " pl = binned_precisions[:, 9]\n", + " auc = binned_precisions.mean(-1)\n", + "\n", + " return {\"AUC\": auc, \"P@L\": pl, \"P@L2\": pl2, \"P@L5\": pl5}\n", + "\n", + "\n", + "def evaluate_prediction(\n", + " predictions: torch.Tensor,\n", + " targets: torch.Tensor,\n", + ") -> Dict[str, float]:\n", + " if isinstance(targets, np.ndarray):\n", + " targets = torch.from_numpy(targets)\n", + " contact_ranges = [\n", + " (\"local\", 3, 6),\n", + " (\"short\", 6, 12),\n", + " (\"medium\", 12, 24),\n", + " (\"long\", 24, None),\n", + " ]\n", + " metrics = {}\n", + " targets = targets.to(predictions.device)\n", + " for name, minsep, maxsep in contact_ranges:\n", + " rangemetrics = compute_precisions(\n", + " predictions,\n", + " targets,\n", + " minsep=minsep,\n", + " maxsep=maxsep,\n", + " )\n", + " for key, val in rangemetrics.items():\n", + " metrics[f\"{name}_{key}\"] = val.item()\n", + " return metrics" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "cvYiSUg7n5rP" + }, + "source": [ + "### Plotting Results" + ] + }, + { + "cell_type": "code", + "execution_count": 7, + "metadata": { + "id": "pG3gTskUfyfy" + }, + "outputs": [], + "source": [ + "\"\"\"Adapted from: https://github.com/rmrao/evo/blob/main/evo/visualize.py\"\"\"\n", + "def plot_contacts_and_predictions(\n", + " predictions: Union[torch.Tensor, np.ndarray],\n", + " contacts: Union[torch.Tensor, np.ndarray],\n", + " ax: Optional[mpl.axes.Axes] = None,\n", + " # artists: Optional[ContactAndPredictionArtists] = None,\n", + " cmap: str = \"Blues\",\n", + " ms: float = 1,\n", + " title: Union[bool, str, Callable[[float], str]] = True,\n", + " animated: bool = False,\n", + ") -> None:\n", + "\n", + " if isinstance(predictions, torch.Tensor):\n", + " predictions = predictions.detach().cpu().numpy()\n", + " if isinstance(contacts, torch.Tensor):\n", + " contacts = contacts.detach().cpu().numpy()\n", + " if ax is None:\n", + " ax = plt.gca()\n", + "\n", + " seqlen = contacts.shape[0]\n", + " relative_distance = np.add.outer(-np.arange(seqlen), np.arange(seqlen))\n", + " bottom_mask = relative_distance < 0\n", + " masked_image = np.ma.masked_where(bottom_mask, predictions)\n", + " invalid_mask = np.abs(np.add.outer(np.arange(seqlen), -np.arange(seqlen))) < 6\n", + " predictions = predictions.copy()\n", + " predictions[invalid_mask] = float(\"-inf\")\n", + "\n", + " topl_val = np.sort(predictions.reshape(-1))[-seqlen]\n", + " pred_contacts = predictions >= topl_val\n", + " true_positives = contacts & pred_contacts & ~bottom_mask\n", + " false_positives = ~contacts & pred_contacts & ~bottom_mask\n", + " other_contacts = contacts & ~pred_contacts & ~bottom_mask\n", + "\n", + " if isinstance(title, str):\n", + " title_text: Optional[str] = title\n", + " elif title:\n", + " long_range_pl = compute_precisions(predictions, contacts, minsep=24)[\n", + " \"P@L\"\n", + " ].item()\n", + " if callable(title):\n", + " title_text = title(long_range_pl)\n", + " else:\n", + " title_text = f\"Long Range P@L: {100 * long_range_pl:0.1f}\"\n", + " else:\n", + " title_text = None\n", + "\n", + " img = ax.imshow(masked_image, cmap=cmap, animated=animated)\n", + " oc = ax.plot(*np.where(other_contacts), \"o\", c=\"grey\", ms=ms)[0]\n", + " fn = ax.plot(*np.where(false_positives), \"o\", c=\"r\", ms=ms)[0]\n", + " tp = ax.plot(*np.where(true_positives), \"o\", c=\"b\", ms=ms)[0]\n", + " ti = ax.set_title(title_text) if title_text is not None else None\n", + " # artists = ContactAndPredictionArtists(img, oc, fn, tp, ti)\n", + "\n", + " ax.axis(\"square\")\n", + " ax.set_xlim([0, seqlen])\n", + " ax.set_ylim([0, seqlen])" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "6T7Pcz-poDFn" + }, + "source": [ + "## Predict and Visualize" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "WnZSlf1EoGys" + }, + "source": [ + "### Read Data" + ] + }, + { + "cell_type": "code", + "execution_count": 8, + "metadata": { + "id": "FS8xLDd9ZJfN" + }, + "outputs": [], + "source": [ + "# This is where the data is actually read in\n", + "PDB_IDS = [\"1a3a\", \"5ahw\", \"1xcr\"]\n", + "\n", + "structures = {\n", + " name.lower(): get_structure(PDBxFile.read(rcsb.fetch(name, \"cif\")))[0]\n", + " for name in PDB_IDS\n", + "}\n", + "\n", + "contacts = {\n", + " name: contacts_from_pdb(structure, chain=\"A\") \n", + " for name, structure in structures.items()\n", + "}\n", + "\n", + "msas = {\n", + " name: read_msa(f\"data/{name.lower()}_1_A.a3m\")\n", + " for name in PDB_IDS\n", + "}\n", + "\n", + "sequences = {\n", + " name: msa[0] for name, msa in msas.items()\n", + "}" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "jacL9LZXoJYD" + }, + "source": [ + "### ESM-2 Predictions" + ] + }, + { + "cell_type": "code", + "execution_count": 9, + "metadata": { + "id": "Kwh2szcbYvKm" + }, + "outputs": [], + "source": [ + "esm2, esm2_alphabet = esm.pretrained.esm2_t33_650M_UR50D()\n", + "esm2 = esm2.eval().cuda()\n", + "esm2_batch_converter = esm2_alphabet.get_batch_converter()" + ] + }, + { + "cell_type": "code", + "execution_count": 10, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/", + "height": 259 + }, + "id": "Qce87TjvbEDA", + "outputId": "1b2415cb-ec14-4163-9466-b621e1d29885" + }, + "outputs": [ + { + "data": { + "text/html": [ + "
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" + ], + "text/plain": [ + " id model local_AUC local_P@L local_P@L2 local_P@L5 \\\n", + "0 1a3a ESM-2 (Unsupervised) 0.801181 0.662069 0.805556 0.896552 \n", + "1 5ahw ESM-2 (Unsupervised) 0.819763 0.680000 0.838710 0.960000 \n", + "2 1xcr ESM-2 (Unsupervised) 0.529522 0.351438 0.500000 0.693548 \n", + "\n", + " short_AUC short_P@L short_P@L2 short_P@L5 medium_AUC medium_P@L \\\n", + "0 0.528245 0.296552 0.500000 0.827586 0.612222 0.344828 \n", + "1 0.543314 0.296000 0.500000 0.840000 0.569258 0.304000 \n", + "2 0.344734 0.204473 0.320513 0.516129 0.410161 0.265176 \n", + "\n", + " medium_P@L2 medium_P@L5 long_AUC long_P@L long_P@L2 long_P@L5 \n", + "0 0.569444 0.931035 0.806507 0.689655 0.791667 0.931035 \n", + "1 0.548387 0.920000 0.937361 0.864000 0.951613 0.960000 \n", + "2 0.365385 0.596774 0.576668 0.408946 0.544872 0.758065 " + ] + }, + "metadata": {}, + "output_type": "display_data" + } + ], + "source": [ + "esm2_predictions = {}\n", + "esm2_results = []\n", + "for name, inputs in sequences.items():\n", + " esm2_batch_labels, esm2_batch_strs, esm2_batch_tokens = esm2_batch_converter([inputs])\n", + " esm2_batch_tokens = esm2_batch_tokens.to(next(esm2.parameters()).device)\n", + " esm2_predictions[name] = esm2.predict_contacts(esm2_batch_tokens)[0].cpu()\n", + " metrics = {\"id\": name, \"model\": \"ESM-2 (Unsupervised)\"}\n", + " metrics.update(evaluate_prediction(esm2_predictions[name], contacts[name]))\n", + " esm2_results.append(metrics)\n", + "esm2_results = pd.DataFrame(esm2_results)\n", + "display(esm2_results)" + ] + }, + { + "cell_type": "code", + "execution_count": 11, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/", + "height": 359 + }, + "id": "WnlwYZeUbgLO", + "outputId": "74a540b3-7042-4028-a122-ef79b589321f" + }, + "outputs": [ + { + "data": { + "image/png": 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idmodellocal_AUClocal_P@Llocal_P@L2local_P@L5short_AUCshort_P@Lshort_P@L2short_P@L5medium_AUCmedium_P@Lmedium_P@L2medium_P@L5long_AUClong_P@Llong_P@L2long_P@L5
01a3aMSA Transformer (Unsupervised)0.8531260.7655170.8750000.8275860.5750570.3172410.5694440.8620690.6010650.3379310.5972220.8275860.8379190.7241380.8611110.896552
15ahwMSA Transformer (Unsupervised)0.8503770.7360000.8548390.9200000.5472820.2880000.5483870.8800000.5814260.3200000.5483870.8800000.9671160.8960000.9677421.000000
21xcrMSA Transformer (Unsupervised)0.6756520.4696490.6794870.8709680.4703730.2492010.4423080.7096770.5080270.3162940.4871790.6774190.8784670.7699680.8910260.967742
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\n", + " " + ], + "text/plain": [ + " id model local_AUC local_P@L local_P@L2 \\\n", + "0 1a3a MSA Transformer (Unsupervised) 0.853126 0.765517 0.875000 \n", + "1 5ahw MSA Transformer (Unsupervised) 0.850377 0.736000 0.854839 \n", + "2 1xcr MSA Transformer (Unsupervised) 0.675652 0.469649 0.679487 \n", + "\n", + " local_P@L5 short_AUC short_P@L short_P@L2 short_P@L5 medium_AUC \\\n", + "0 0.827586 0.575057 0.317241 0.569444 0.862069 0.601065 \n", + "1 0.920000 0.547282 0.288000 0.548387 0.880000 0.581426 \n", + "2 0.870968 0.470373 0.249201 0.442308 0.709677 0.508027 \n", + "\n", + " medium_P@L medium_P@L2 medium_P@L5 long_AUC long_P@L long_P@L2 \\\n", + "0 0.337931 0.597222 0.827586 0.837919 0.724138 0.861111 \n", + "1 0.320000 0.548387 0.880000 0.967116 0.896000 0.967742 \n", + "2 0.316294 0.487179 0.677419 0.878467 0.769968 0.891026 \n", + "\n", + " long_P@L5 \n", + "0 0.896552 \n", + "1 1.000000 \n", + "2 0.967742 " + ] + }, + "metadata": {}, + "output_type": "display_data" + } + ], + "source": [ + "msa_transformer_predictions = {}\n", + "msa_transformer_results = []\n", + "for name, inputs in msas.items():\n", + " inputs = greedy_select(inputs, num_seqs=128) # can change this to pass more/fewer sequences\n", + " msa_transformer_batch_labels, msa_transformer_batch_strs, msa_transformer_batch_tokens = msa_transformer_batch_converter([inputs])\n", + " msa_transformer_batch_tokens = msa_transformer_batch_tokens.to(next(msa_transformer.parameters()).device)\n", + " msa_transformer_predictions[name] = msa_transformer.predict_contacts(msa_transformer_batch_tokens)[0].cpu()\n", + " metrics = {\"id\": name, \"model\": \"MSA Transformer (Unsupervised)\"}\n", + " metrics.update(evaluate_prediction(msa_transformer_predictions[name], contacts[name]))\n", + " msa_transformer_results.append(metrics)\n", + "msa_transformer_results = pd.DataFrame(msa_transformer_results)\n", + "display(msa_transformer_results)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/", + "height": 359 + }, + "id": "6iPBer65nPRI", + "outputId": "10f21020-80a7-4a87-9343-2cb6df0a3890" + }, + "outputs": [ + { + "data": { + "image/png": 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\n", + "text/plain": [ + "
" + ] + }, + "metadata": { + "needs_background": "light" + }, + "output_type": "display_data" + } + ], + "source": [ + "fig, axes = plt.subplots(figsize=(18, 6), ncols=3)\n", + "for ax, name in zip(axes, PDB_IDS):\n", + " prediction = msa_transformer_predictions[name]\n", + " target = contacts[name]\n", + " plot_contacts_and_predictions(\n", + " prediction, target, ax=ax, title = lambda prec: f\"{name}: Long Range P@L: {100 * prec:0.1f}\"\n", + " )\n", + "plt.show()" + ] + } + ], + "metadata": { + "accelerator": "GPU", + "colab": { + "collapsed_sections": [ + "U0ukYqqzateL", + "q1eZWXv1bxGl", + "i7iXPaDKZ5vx", + "rb4cDoG2ns91", + "tV3WCbn6aXL7", + "mqwybh2Tn_Ou", + "lW5thQpSn0Rp", + "cvYiSUg7n5rP", + "WnZSlf1EoGys" + ], + "name": "esm_contact_prediction.ipynb", + "provenance": [], + "toc_visible": true + }, + "kernelspec": { + "display_name": "Python 3 (ipykernel)", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.8.13" + } + }, + "nbformat": 4, + "nbformat_minor": 1 +} diff --git a/esm/source/examples/data/1a3a_1_A.a3m b/esm/source/examples/data/1a3a_1_A.a3m new file mode 100644 index 0000000000000000000000000000000000000000..96e7ec729550541b5e74d9ba782a07c05b49097c --- /dev/null +++ b/esm/source/examples/data/1a3a_1_A.a3m @@ -0,0 +1,2048 @@ +> +LFKLGAENIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKTGVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTTSVDEVLELLAGRK +> +-MKLKTELIKLNANPTDKTEAIKVIAQLFVDADCTTAEYLSGMLAREEQENTYLGKGVAIPHGTPEVRDQIKETSIAVMQIPQGLEWGEDE--PVHLAIGIAANSDEHLQILGKLVRILNNQEQLDTLINTDDASVIQAALSD-- +> +--MLQKENIFFNLCSDSKETILKDLGNGLLATGYVTNDYVKSIIKREQEMSTYLSNGVAVPHGLTSSAEGILKNGVAIATIPDGIDWGNGQ--IVRVIIMIAAERRAHMNVLAKAAKLCSDESKVKAILTMTVD-EIYDKCRF-- +> 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+PTSGVEELVRIDARVVNKVDAIRQVGQLLAAAGCVSPDYEDSMVAREEIANTFLGAGVAIPHGLGEDKGKVRRDGIAILQLRDGVEWNPGQ--RAHIVVGIAANSDNHIAILRRLTRLIQDEARLEDLRTTGNPDDFRRALWAD- +> +TDILSLKSIQLSAVFSHKNDAIYAAVKLLMGSDVIKQHHLGGIIGSKLIASIWFRSGVAVIYGITESYQLVMRDAVSVVQIPAGVEWQDER--RVYLVIAVITCADLHIKILKKIAPILFDEQKLKELSVIEDKQKIITALLGR- +> +RCALTSKNIQLGTKIASKQAAIEEAGRVLASLGCIESGYIRSMFEREKMETTYLGKGIAIPHGLPKDRALVHQTGISVVQIPAGVCWGPGQ--IAYLIVGIAAKSDEHVSILAAVAEICNDSGAISRLARTDDVEEIIYALTTQ- +> +MTILSKDRISLQTSASDKADAIRKAGQLLVATGCVLPEYVDGMLAREQSMSTSLGNGVAIPHGVYENRGHILKTGISVLQLPAGVDWDEGE--MIYLVIGIAAQGDEHVGVLANLAEVIDDENNLAELFQTTDPEVIVKYLGA-- +> +MSQLLKSHIFLQQFAPSKYQALKLACLKLVEAGMVCPGYFHGMCRRELLSSTYLDNGIAVPHSVPDTRSEINYSGMIIIQFPRGVNWGNND--RTFLLCALAARGKEHLQMLSHLACSLDDTDLCRKLAVTEEVEHIYQSVTR-- +> +QDVLTRDLVVAPGTARTKEEAIREAGALLVGCGSVTPAYVDAMAAREQLVSTYMGSWLAIPHGTDESKGDIVASALCLIRYDEPIEWGAGQ--PVRVVVGIAGVGEEHLSILSKIALIFSDPTEVEKVLAAAGPDELYALIQQ-- +> +-MRFERNLIFIKTDFRDKTAVVEFLGGQLVQAGAVQPAYVQAMHQREQDVGTYITEGVAIPHGTEGSRSLVNRAAIVALKIPRGIEWSDGK--PVFLAFGIAGNEEDHVSLLSELAIMLMDADQKAKLLAAENEDDLFACLNQ-- +> +MLKLSEDSLHLQCRAANKNEAIKIAANALEKAGYVKPGFMEGMLAREKSVSTYIGAGVAFPHCAKENLDLVLKTGFQVFQFPQGVSWGAGK--VVFVVVAVAATGNQHIQVLADIASLLGDEVKTTLLASAKTKQEFISQFEK-- +> +MLKLNENDLFLHCQAANKNEAMQLAAAALEQGGYVKTGFFHAMQAREESVSTYIGAGIAFPHCAKADTHLVINTGFQVFQFPQGVSWGAGK--VVFIVVAVAAQQDEHIQVLAAIADLLGDEVKTTLLANANTKAGFIEQFEK-- +> +--MYDEKNIFMNCKFADKETALNQVLEVMLAGGC-DQEYVDSILERQKIASFNLGNLVAAPHGTYEISKKVKKPKIFIWHLKEELLWDGE---PIRLILGLYLQPNNQLEALQTVAINTIDEILFNNLLAKPTLNKLIKFTSE-- +> +GAILAREGIKLGLPTVSMEEAIVAAGELLRDLGYVDDDYIPAMIRRNEEASVYMGLGLAIPHGTEDAKRNVKKSGIIVMQYPDGVEFNGG---TAQLVIGIAGVGDEHLEILGQITEAVTEEEILEELKKTTDVDYILKTFANM- +> +GEIIKESMIVVDAKVRDKFEAIKMAGEILVKEGYVEPEYIDAMFERERMLSTYIGNFIAIPHGVGESKKYIKKTGLSVIHVSDGVDFGDNN--IVYLVIGIAALGDEHLNILANIATLFENEEKVKKLIQNPSRKEIFDFLNGR- +> +LSNEFQKHICLDYECTTIEEAIHKAGNLLVQTGCVKPPYINGMLRREQETSTDIGFGVMIPHGTEDTLDFVLKPGISIVQIPHGISYHGNP--I-HLVIGISSREEDPLQELMQITDILLKPEKCHQFLNASSKQEFIDMINQN- +> +PQILKVENIRINQQAASSDEAIVRVGNALKDAGYIEEGYIQGMLNRDHNLTTYIGNDIAIPHGEYEVKDCVKQTGLAVDIYPDGIAWGGG---IVRIVIGIAATTDEHITILQNIAEQLGDMDVVEQVVKGSPE-FIHSVLTGG- +> +LNDEFQKHICLDFECTTIEEAIRKAGDLLVQCGCIKPPYIDGMIRREQEHSTHIGFGVMIPHGTEDTLDCVISPGISILKISNGVPYHGTM--I-TMVIGIASREEDPLQELMQITDILLTPEKCDQFLNASSKQEFIDMINQH- +> +NDILNPANIRLNQKASCSDDAIVSVGKQLMNAGYIEEPYIQGMLNRDHDLTTYIGNDIAIPHGEYEVKDYVKKTGLAVDIYPDGIEWAGN---KVRIVIGIAATTDEHVRILQNIAEKLCDMEMVEKVVSGNQD-TIHQILAIT- +> +MEALDKKMIALNQQVATQEEGIRLAGQLLVDGGCVEPEYIDAMQARNQDVSVYMGNFIAIPHGTEDGMKYIKKTGISVVQVPMGVSWGNPDN-DVTVIFGIAGLNGEHLNLLSQIAIYCSDVANVAKLADAQSEDEIINLLKEV- +> +ERLLSEKTVLLGASFPDKVAAIRACGELLVAAGYAERPYIDAMVARDEMSTIYIGNGVALPHGTEASRRYVKRTGLAIVQVPGGVDFGKGN--VARLLVAVAALGEEHIDLLTEIAQICVDDEMLDRLINAATASELLSVIAPE- +> +LPILMKENIIIEKQTMSVKEAIDKVGAMMIKSGYVKKGYIDGMHRRDEDLSVFLGNLLAIPHGVHDVKDEIIASGMVVLIVPDGIDWHGN---VAKVIIGLAGKDGEHMSILANLATIFEELETAQKLVDSRDIDFIYQTMTQ-- +> +KPVLIKENIVLDCKAVTPEEAIIHAGELLLRSGYIKSGYISGMLSRDENFSVYLGNMLAIAHGEKGVRDQILGTGMSVLICPDGIDWHGN---LVKIVMGLAAIGDEHMELLMHCANIFSDRERVERLVRCRDRERVYRMFGGI- +> +MIEISNESIWLNQSFDSWEQALNKIGEILREAGYITKEYIASMIDRQKLASVYIGNFVALPHALA-KDEHIIKENIFLFQVPDGVDFGAEE--EATILFVVVLKEKHQLENLQELAFLCSDVDQVMALSDAQTVDEIQIILKKA- +> +MKLLEEKNISLNQTFKTPQEAIIYAGEKMKSLGLIKEEYIESMLVRQDKLSVYIGNFVALPHGEV-QDEFILEEGIFVTQVPDGIDFSNTE--QATIIISVALRKESQLRILQELAFFCSDIENVRKLSDEVDEKQFVTFFNES- +> +QTILTADKIKLDAKPATKKEAITMAGQLLVQAGCVSEDYIQSMMEREELQTTYMGFGVAIPHGTKEAKTFIRSTGISVVQVREGVDFGNGN--VAKILIGIAAVGDEHLDIIQNLALLISEEENVDKLVHADTAKAVIDMIEQG- +> +KISVEKENIFLNLSKVTKEEAIRMAGNKLLEAGYVADGYVESMLYRENIMSTYMGSGVALPHGDRESEQLIIESGIVFLQFKEGIDFGDGN--IAEIVIASSGKGNNHLKILASLATLLKRDEILNTFTSSNSVDEIYEILRNN- +> +RGVLSLGQVRIRTGPVTKEDALHEAADILESAGAVTSGYLDAMYQREQAVSTYMGGELAIPHGTSETAHLILESALSFVRYDDGIDWDGDL--V-TFVVGIAGKGDEHLQMLSRIALLFADPVEIARLKSAATPEELYDMVVED- +> +KEILSMENIKLNAQFKNKEEAIRYTGEILVANGYVQPNYVEKMLEREEVTSTFMGNFVAIPHGTEDSKDEVIETGISVVITPEGVSFGDGN--TVKILVGIAGKGDEHLEVLSKIAIVLSEEDNIESLVKSTSKEEIIRIFDEV- +> +PEVLCEQNILLNIESETKNEAIKRVGRLLVENGYVDEKYIKGMIKRNDDISTYIGNGVAIPHGMNEYVKYIKYSGIVIAQYPHGVDFGEGN--IAYLVIGIAGKGDDHMSILSKIAIACQDKKNVQKLVEENDKNVMINLILEG- +> +MSILSKEKILLSAAAKDKYEAIRIAGELLVKAGHVEPAYVDRMIDRENIVSTYMGNGLAIPHGTKEGKDLIHSTGLSIVRFPDGVDFDGDE--PAFVVIGIAGAGGDHMQILTNVAMIFSEDESLEQVMNAPTEEAIMAIFEGG- +> +-MYIPIERIIVNQQFASAEIALQEIGAYLVQQGIVAEPYVDSLLRRQQQYGVYIGNFVALPHAEEQAHQWIMEEGVFLFQVPDGVDFGTAA--EATILFVVVLKE-KQLSFLQEIAFFCSDIQNVRLLSDASSPQEIQQILLDE- +> +KEICSAASIVLNSKISERDEAIRAAGKLLVNGGYVSEKYIDLMLARERIASTYMGNHLAIPHGTDGAQSEIITSGISIIQLPDGVDFGGGE--LAYMVIGIAGKDGTHLDMLGQIAVACMEPDTVELMRRATSKQSIIDALGVA- +> +--MITEKQIMLSCSACSKEDAIRLVGQRMIELGFITAEYVNEMLEREKICSTYIANGIAIPHGLNNRSASILKEGMVIAQFPEGVYYDSE---RAYLLFSIAGCGERHLKILSAVADFIENNEVNQKLRTVSSLTPFYRMIEYF- +> +MEILKLDNITLSASFQDRDEAIKAAGRILVENGYVAPEYVDCMLQREAVISTYVGNNVAVPHGISGSEGFIKESGISVVVVPEGVQYSEHD--VAKLIIGIAGRDGQHMDILGQIAMICSEQENVDEILQAKSAQEILEIFQKE- +> +MSILKAENIKIGASVGSKEEAIKLAGQVLADQGYVNEQYIDKMFAREELTSTYMGNLLAIPHGTEDAREDVTQSGLSILLLDHEIDWNGNP---VQLVIGIAGKGDEHLEILSKIAIACSEEDNVRALLQVKTAEDVLDFFSGV- +> +KKVLELENIKVNLNSVSKEEAIRFAGEHLLNLGYVQKEYIDSMLRRENNLTTYIGNHVAIPHGDTGSASLVKTTGIVFHHYKKGVDFGKEK--A-HFIIGIASKDNYHLEILANIAEIFSDADLVKSFLKKVTVEKVFKLLQGE- +> +IEYLPEKNIILSGKASNKEEAIKEVADILITNNYVSEEYLDKMYEREESVSTYIGNYLAIPHGVDSS-AYVNKTGLAFIRYDKPIDWDENK--V-YFVIGIASKNDNHIDILSKIAILFSDENNVDGLKAAKDEREIIETINSV- +> +EMEITFQDIELNMAFQTKEDSIRYAGRKLVERGYVVEPYIETMIQRDILTTTYIGNGVAIPHGTDEARDFILKSGIVVLQVPQGIEYN-GE--CATVIFGIAGKNNTHMDILSQIAIVCSNEDNVKRITNAESKEEIIQILNGK- +> +SEILKKENIYLNCELEDKEAVIRRIGEIFVKDGYATDQYTRAMLEKEKVFNTAIGSSLAIPHGIESMKDQVLQSGIVVMTFPQGLPWGEQE--IVKLVIGIAARGDEHIDILSNIATHCASEEETEKIIRSSRD-EIYEFFASV- +> +MELLEKKNIRINCQPKSKNEVIQSVGQMLFESGYVKKDYIAAMVEREKTFSTNIGNGIALPHGTENAKREIISSGIAVQVFPEGTEWGEE---KVQVVIGIAGVGDAHLDILAHIAEKLSDPSEVGCLVKSDEE-GVYRMLTGK- +> +-MVLEKRNILLNQRPDTKENVIKRIGAIFSAEGYTDDNYTQAMLEKETIFNTYMGNFVALPHGIEAAKKDIRKTGIVLMTVPEGQEWDAAE--KPKVIIGVAAVGDEHLEILSKIALSFSDADGIDRLLGMSED-DISAIFEG-- +> +-MNISNECTYFNLDSMQKMEAIKLAGEKLLENGFIEEAYIQSMLDKEKTDLTYIGNGIAIPHGLNDAKQYVKKSGIVLLHFPEGIDYDEN---KVFLMIGIAGKDDDHLEILQDIAIKLSEMDFVNSLLSSETKEEFITLFNS-- +> +-SSLTADGIHLGRTATSRTDAIDQCGRALVELGAVEVEYLAAMHEREESLSTFIGEGVAIPHGTDQARQYVKRTTLVVLQFPNGVEWGGN---TAKVCVGIAANGSEQVGILSALAHVLMDSTKAEQLREARDAGTVLDLLQS-- +> +-DLIQQAGIQLAAAASSSEEAVASCGQLLFELGAIETEYAAAMWEREQIFSSAIGMGFAIPHGTDESRKFVNFDQLVFLRLENPIMWGDE---EVYCVLGIASQGDAHVDILGNLAELIQDPAHLATLMNSNSPSEILDLLLS-- +> +-QRLPRELFVPGFVAADRTEAIRSLGSLLIQHGIVDDGYVASAIERERLSSTLFAEGLAVPHAMGL---TARRTALAVAVSPDGVRWG-D---RARLVVFLAISPEQFQSLFDRLVELFADPTSLGRVVRSGTDYDAEDLFDA-- +> +-SILQPSSVRLGLASVSKQEAIRMCAQVLVDCGAATEDYFAGMLAREQQISTYLGEGVAIPHGTNEARAHIRSAALGFLQFPDGIDWDGN---EVKVCIPIASASDEHLGILASLAEALMEPEAAERLRVTDSVAEVIDLLTP-- +> +-PMLRKENILLNQPKADRESIIRRCGRMLVDSGYANERYIEGMVKRDNSFTTYIGNYIALPHGEEAYKVDIIATGIVVLAFPEGIDWQ-T---LAYLVIGIAAKGDEHIDIMGNVVDNLETGDDVEKLVREGTVEDVYKMLAG-- +> +-DLLQLAGITLDATASSREEAVAICGAKLIELGAVSPEYAAAMWERELTFPSELGDGFAIPHGTDESRVFVNFDQLVFIRLQRPITWVNE---EVSVMVGIASAGDGHVEILGNLADLLMEEDKAEILRTSNNPEVIRDLIVK-- +> +-DLLDPRAVLLHESAPDREAAVRRCGRALADVGAVAEPYVEAMLERERSLSTYVGEGVAIPHGTNASKGDVLRDAICVVRFPGGVDWDGE---HVTLCVGIAAKDNGHVPLLAALAEILLDPDRARALREATEVSDVIKELTA-- +> +NDVLVLKNILVNQKSVSKDAAIEKAGQLLVDGGYVLPEYIVAMKEREAQLTTYIGHGVAIPHGVGVAKDKILKSGISVIQYPDGIVFDDK---VAYLIVGIAGKGKEHLKILSNLAEFIIEEELLKELFSTEVATKLYSAFTR-- +> +FSCLKISDIRVQLPPMEKFDAIRLAGRMLVERGSVSEEYIEAMVEREKTVTTYLGEGVAIPHGVGTAKQYIKSTGLVVLQFAEGVAFEDG---SAKLLVGIAGLGEEHLPILQAVAHIIMKGDLLKELQETDDPEFILRTLTS-- +> +KPVLIKEAILVDQNITDLNQSIDLAGKLLLDNGYIDEEYIESMKEKEHPYTTYLGAGVAIPHGMSDGFKYIKHTGISVLQIPNGLNWLDE---KVYIIIAIAANSDEHMNVLASLSDALESEEDAQKLWTTNSVDKLFEILSN-- +> +MLTLNLSSIFLNQSAEDKLQVIELIGQKMVEVGYTTEAYTVGLKAREAISSTFLGNGIAIPHGTPDSRDAVQKTGVVILQFPQGVDWGEGD--KVFMAVGIAARSNEHLQILSGLTRVLDNDDLCGHLAKTGNPQDVIEAINPQ- +> +-MQLSCADIHFDREIKTKDEALQRVVGRLTEAGHTTAAYLNGMRDREGQISTYLGNGIAIPHGTPQSRDAVLKTGVKVLACPQGVDWGEQQ--TAYLIVGIAAQDSEHLDILRQLTHAMSDERVPEAYQRTRAPQAVLEILAGI- +> +MFNLPENNIHLAAQATDKQQAIEMAAAALEQGGYVESGYLQGMLGREQQTSTFLGNGIAIPHGTLETRGLVKNTGVAVFQFPQGIEWGEGN--KAYVVIGIAARSDEHLSLLRQLTHVLGDEDTAAKLATLDDVKKFRAILMGEA +> +MLTINRSNYYLNCKAENKKDALRIISDEFIKSKNVTTDCFYALSKRENQISTYISNGVAIPHLSKDDRTIILKSDIKVFQFPQGVMWGESH--IVFITIAVLSNDNDHIDTLKALTPLIKNDVAIDILSVTKHVDDFDKILSR-- +> +IDDITINNLHLGCQAKNKAEVLSMVGRSFKEKGYVSQDCVAFLNEREQQVSTFLGNGITLPHLPKSATNIIVKKGVEIFQFPDGVIWDRSNSSVMFIAIGVIAKEKEHIDVLKQVASIFSDEIIANALSLISNKQDFLRILNR-- +> +MMKITADELTLGCRAKNRNEVLRQAAFELAARGCVDIGFSKALLDRENDVSTWIGAGLAMPHINRRDAGQIIRSGFHFLQYPEGVSWDKSH--VAFLVVVVAAKDGDHIAMLSGIADLLVNERKVMRLSMADSKTAFLNLLAD-- +> +--ILVAESVVLSGSSTSRDAAIDEAGQLLLARDAVDEGYLRAMHEREESVSTYMGSFLAIPHGTNAAKGHIRKSAVSFVRYPEGIDWNGK---EVKFVVGVAGVNNEHLHILSSIAKVFTDKAQVAQLEAATSAEEILEIFRK-- +> +--ILPASNVRMGLASVAKEDAIRQAGDVLVASGAADPAYIDGMLLREHQTSTFLGQGVAIPHGTNESRTHIRSAALGFLQFPDGVDWDGH---TVNVVIPIASNSDEHVSILAALASVLADKERSQRLRTARTPDEVISLLTP-- +> +--LFTPDHVLIGAQADDKWEAIQQVGGLLVRLGLVRDDYIDRMIERERVLSTFIGNGVALPHGVGAADPGILKPGVVIAQYPDGVTFDEGN--KAYLLIAVVG-GEQQMGLVSRIAFMIENPDTVQALVRAGSPLEMHRRVSA-- +> +--SIDRCSIQLGLESVSRAEALRAAGKLLVDQGFARESYADAIAERDRLASVYLGMGVAIPHGTRAASDAVIKTGVVLQQYPEGIDFDGE---KAYLLFGIAGRGSEHLKVLANICGILENEKVLAKLKTTDDIDWILKVLS--- +> +--VFVLDNIMLGMKADTKQEAIVAAGELLFKQGYINKPYIQGMLDREETTTTAIGFGVAIPHGSIATKKEVRETGIVFLQYPQGVSFGDE---IVHYVFGIAAAGDEHLEILAQIADIVEDEEKLETLKTTTDKQTVMSLLGL-- +> +MFVLEPKHVHMNLRAKDKATALQCLVNILVEDQLTTAEYLTGLEAREAQGATYLGQGIAIPHGTPQSREFIKETGIRLAHFPEGVVWDGEH--KIYLAVVIAAKSDEHLQVLQILTRALNHD-VSIQVQTATTAEQIIDILQVR- +> +MLTLTPEDIRLGCQAADWREALSLASQELEKAGRTTPEYHQGLLDRENQSSTVLGNGIAIPHGTPDSREYVRSTGIRVLQFPEGITWHDGA--KVHVLVTIAAQSDEHLDILRHLTRVLDKPGLAERLANATDRNELLAALSRT- +> +MFPMTTQDIKMNQTLASKQAAIVALSRWLEQDGYVKAGYEAGMLEREAQAATYLGQGIAIPHGTRECRHLVQKTGIKALHVPEGIDWDDGE--KAYLILGIAASSGEHLALLRQLARVLSRDDLAETVRKAQHGEDIFNLLHEY- +> +TLSLEPKQILLKQSLASKTEVLTLISDTMQTLGFVTGDYTKALADREAKVSTYLVNGVAIPHGTNEAKSQVKKTGLVIVQVPAGVTWNDQG-DQAHFIVGIAANGDEHLGVLQQLTQVVMDEAKAKHLGSNANVQDIVQALNTN- +> +MIRLTTENVQLNTQVTTKAEAIQQVGTLLAKAGHIQPGYIDSLFAREAIANTYLGNGIAIPHGQPEHRDLIVNTGVAVVQIPNGVTWNAGE--TVYLVVGIAARSDEHLNILTNLTHVLDDPARVERLAHTKNAQEIVDELMVT- +> +PVLVASELVRVDAQARDKADAIAQAAQLLVAAGCVPPAYAASMLRREALANTFLGRGVAIPHCTGDDRHLVQRDGIAVLQLRDGVEWNPGQ--TTHLVVAIAAQSDTHITLLRRLTRLIQDQPRLDALFASDDPQAIVDALSQD- +> +--VLRKENILVNCPVETSDEAILSVGKMLVDGGYVTPEYIQGMMERDHSLSVFMGNTLAIPHGEYEYKKFIKHSGIVIKVYPQAIDWHGE---KVHLVLGLAGIGEDHINILSNCATVFSEMSDVERVIQNQDVEEIFNLLTAE- +> +-VQV----------------LAPLTGVMVPIESVPDPVFAQKMVGDGFSIDPFDGTVFAPVSGEIADLQNA--HHALTIRTPEGIEILIGR--G-HVARGDVAAGDKLITF--DVDRVAREAKLLTQVVANMDA------IASI- +> +-VAITESLVRLGLTARDKEDAIRQTAAILAEEGSVGAGYGDSMLARERQVPTYLGSGIAIPHGMRGDAAMVRRTAVAVAQFPQGVPWGDGQ--TVHLAIGIAAQSDEHVQVLAALTGVLQEPELAEALGRTRDKGEILRALGGA- +> +MFKLTKKDIHLNQSATGKIQAIKSIAQALVDADLVEDGYSEEIQQCEQQAASYLDNGIAIIST-TVFRHLIKKAGVQIFHFPQGIVWGENG-KLAYIVISIAANSDEQLTFLDKLTRNISKDGIEEKIKNIKTVEDVINILTGK- +> +DLKLTIDDIRIISGCYSKQDAIQSVSEAMIKAGLVKDDYTQAMFDRDTQISTFLGNGIAIPHGTTDKRDSVIKTGLKIIYYPKGVLWDQDD-NIAYVVIGIAAKANEHLDILRQLTKAVIAEDTLDRIKTIKTAENLLEILQGS- +> +--ILKKENIKINQSAKNKVEAIKQCGELLKELGYIEESYIESMIEREKKFSVYIGNYLAIPHGMNET--GVIKDGIVVIHYNEPIDYDGS---PVNFFIGIAAKSNNHVDILANIAEKMMELDFVEELIAKPSKDRILEEF---- +> +--IFSPENVLINQNAKTKEEAILQCGNLLKELGYINDEYIDSMLERERHFSTYIGNWIAICHGMDGR--GVLDNGIVIIHFEKPIMFEDQ---PTHFLVGLAAKNSQYNDFFEKMSIKLLEIDFVEELLKHPSRERIFKEF---- +> +--VLARDRILIHGVAQDREGAIAEAGQLLVDSGVVDASYVDAMHQRERSVSTYMGNLLAVPHGSSEATPAIKRTGISFVRYPDGVSWKGE---EVKYVVGIAGKGEDHVTLIGKIAEVFLSEEHLAKLAAAQTQDDILALFGS-- +> +--QIKDEFIFIDEDLKSKEDIFSFLENVLIKGEIGNKDFIDSMKQRDKTASVAIGNYLAIPHCDYSFSSNIKKQELVFIKLKNKVMWDEN---EVLFVIALILKNEGQLEILANIGITFSDEDLVLEFHKLTKKEQVNKFIEEN- +> +--YLNTNNILIGVDIKNKNDAFNKVFECLKKQNAIEDKYLNSMIERDKNSSVAIGNFIAIAHGTVETKDLIKKDAMCILVLKNPIDWDGN---EVKVVLGLALSGDKTMDVIGNIGVAFSDEEEVKNFYKDLTSNEVLKWLVAH- +> +--IKNKESVFLIDKFNSKIEAIEFVGNKMVELGYVDKQYIDSMIERDKTASVAIGNYLAIPHGNSDGFKYIKNSGILVVKLKEALTWDDE---KVNWIVALALEGNNQLEALQNLAIAFSEKSEVESMNKLNTLDEIFDFFSNL- +> +--IKSKDCVFIVDSFKDKNKAMEFVGSKMVELNYIDKEYIDFIKQRDQLASVAIGNYLAIPHGSLTGEKFIKNQGIIIVKLNKTMNWDNE---KVNWIIGLSLLGDKQLEMLQTIAILFEDINKVEQLTKLNTIDQIYEFFTNL- +> +--KISQENVLVDLNFANKNEVLNFIGAEFSKRNWTKPEYTQSLINRDQADSVAIGSYLALVHGQQQDCDLILQEGVLVIRLANSLQWDQQ---VVKWVIGLALKGDNQLEFLQNIAIAFSDEADALKVYQNTSVKQICDYFNNL- +> +--ILKRENIFLNQELNSKKEVFDFVFKIFFNNNSVKKQYLKSMIKRDENSSVALGNYLVLPHGEADSEKYILKNDVCIVHLKNELIWDNQ---KTKIIFALALKGDTQMEFIQIAGISFSDEQKVKELVKNINKEDIINFLKNI- +> +--KLLKNNIYINVYLKNKQEIFEFVFKKFKEDGAVLDSFLPAIVERDKAASVAIGNYLFLPHPVYDEIANIQKEKMVFIGLKDVINIDGQ---PIKFICGLALKGEHQMDALQSLAIAFSDPEEVEKLVDDLTQDKVLEFLAKH- +> +--NLKLENIHLNQIITSKKQAFEKLIRIFQQKNCCEFEYLQSMEKRDLESSVALGNFLALPHGNFEGNNLIFRNCIEIIHLKNTLNWDGQ---PVKFVIGLAVKNSEQIDYIQKIGLAFIDVEKVEEILDDLSKQKILDWIINN- +> +--NLKVENILLNQVITSKKQAFETLIKIFMKKNCCNLEYLESMEKRDFESSVALGNYLALVHGTYEGSGLVFQNCMQIIHLKNTLEWDGQ---HIKFIIGLAVKSSEQINYIQKIGLAFIQKEKVESIMDYLTKEKILVWINTS- +> +--KNIYKKIYLNKTFNSKQECLDYLKELLKQEN-VSLEYIDSINKREEDCSFNIGSKIAIPHGIYEGMLSLKNSLIVVIHLQKPLIWDNS---EVQLVIGLALKQEDQIDMLQNIAINAMNDDLFNDLLN-PTIDKVISFCTKQ- +> +--MIKLENIKINKNFKDKYEIFRVAEEDLINLNSVKKGYQQAMINRDKSVSVSLGNYLFLPHGEDGSQDLILKNEVLVYHLKDVISIGDN---EIKVVVVLALKASNQMEYIEKIGIAFSDIDEVEKVMDQVTAQKIFDFLTQE- +> +-----MQSVKMNCSYKNKKEALKAIINDLKEKG-VSEKYLNSIYTREKMASFNIGYKIAIPHGTYEESKNISETWLVIHHLKKPIFWDDS---LVQIVVGIAIKNQDQIDLLSNLAINAMNETFYEDLLK-PTEEKLNKLIIAE- +> +-----KENIFLNQEFKTKQECLDYLKSIFKKEN-IDDRYIESIDLREQVCSFNIGSKIAIPHGTYDGMLYLKNSLITVLHLQKPIIWDDS---EVQLIIGLALKQEDQIDILSKIAINAMNDELFEDLLN-PTVDKIIDFSTKE- +> +KGVITTDLIFLDSDLDNQEEAIQHIVDTAEFVGYVEDTLFQAVMKREDEVPTAIGYDIAIPHGKT---EAVLKPFIAFLRVKQPFQWAKENEEMVRLVFLIGVPQKMHLKFISQLSKKLLDDDFRNKLLKETDKHKIYEHLSS-- +> +AEVLVKEAVILAGNVASKQMVFACLASQFKKAGVIRDEYIKSLEERESIGSTFMGNFIALPHGRS---ETVIRPGIGFLRCKEPFRYQSFDE--ERYVFMLAVSKNEHLRVLASLARLLAHREFIEKLEQVETYEELLAIVKT-- +> +ID-IDKNSIMIDVQETSKERLLSKMVERLDNCKLLLEEAEHSIMAREKLMSTGVGNGVAIPHSKT---NSVKSITLTIATVKNGINYKSPDNKKVFVIFMLLSPKD-NLKVLTSIAAILRDTHFIEKLINAEKSDDILELIAK-- +> +SRILTPRRVNLNLQASSKEEAIIELTDLLFSDGAISQAFIKDVWLREAEGSTGFENHIAIPHGKS---SAVKQTTLAIGRSQQDIPWETLDGSQVRCIILFAVRLTPIFACCPRWPVRWPMMRMIAQLLVENDPSEIIRLFSQ-- +> +TEMITINTVEFNLNLKTQGEVLEKITDILFKDNRIEKETLKGYIDRENECTTGIGFGLAIPHCKV---ESVIKPTIVCLKLNQAIDWNSLDEEPVNIIIGLAIPKTLHLEILGKLASNLMEDDFKRTLFNINDKNKLVTFLQE-- +> +KTVISTDLIFLDSELKQQAEVLSFIIETAEFVGYVADELYEAVKRREEEIPTAIGYDIAMPHGKT---DAVVHPFIAFLRTKEPFQWTTKNEEMVRLVFLIGVPKKLHLKFISQLSKKLLDTEFRAKLLIETDKNKIFEQLSS-- +> +RKLIEKELVLLDMALSTRDDVLTAVSDKAYALNFIKAAFIDGVLEREGLIPTSIGFKVAIPHVKS---KVVNSPFVSFVRTTEAFRWDDRNDEDVDFIFLIAIPENLHLRFLSAISRKLVDEEFRNSLRNAKTSTEAYDILQA-- +> +SKVLNVNHIKLNMVAKTKKEALEELTDLLVQDGSVIDEFLRDIWLREEQGATGFENHIAIPHGQS---SAVRHTTLAIGRTPHKIPWETMDGIDIHCIILYAVRSTTHIRLLTQVSCALADERIIAQLLEESDPKNIIEMFNA-- +> +AEVLLDEMVILCEPFKDKDDMFDAMTRKFEEAGFVSKAYKEALEYRETLGPTYMGNFVAIPHGKC---KEVIKPGIGFCRCKEPFIYESAGE--SKYIFVLAISDDYHLRVLATLAGMLAHEEFLELLGTAESYEDLIHGISN-- +> +LLFDEKLIVFPEDSFAAKEDVIRCLTHLE--NSRVLDRYEQAVLEREASFATYTIDGVAMPHAKS---EGVGEAFVAFARLKTPVPWGTESGEDARVVFLIGVPQNLHLKILAALSKKLIHESFRQKLSEAASEKEVYQLLQE-- +> +MGINVETKVILNNKYTDKKSFFAELCEVIHNMDEKVITIKEALEEREKVVTTGFGNELAIPHGKV---EGLISPYLFFVRVKNPIEWQAMDDEKVKFIFVILVPSNNHLKVLSILSYNLMDSEYQKMIKTVKDEEEAKNIIEK-- +> +-MFSEKQVVFLEEAFPRKQEVIHHLTHLA--NERILDRYEQAVLAREESFPTYTIDGVAMPHAKS---DAIGEAFVAFARLKTPVHWGSEEGEDASVVFLIGVPENLHLKILAALSKKLIHDSFRQSLSEAQSVQEVYQLLQE-- +> +KEVIKKEYIFTGMEVTTKEEALRAIAERAVELGLCREETYQGFMERESQGPTGMQDGFAIPHTRC---ESVIQTGIVVMKSTRELEWESFDGKPVQIMIALIVPKNEHIQILASLSRMLMKQDFRRKLTETDSAEEIFEVIHQ-- +> +-MLIARENIFLNKNFSSKGEIFQFLSQQAVERGWAAEKIEADLWTRENQYSTGFEGQIAIPHAKT---INVTEAGVIFIRLQQALDWESLDDSPIKIVFGLFVPELLHLKIINSLASQIVEDDFRQQLFDAKSEDELFNYMQS-- +> +EELINDELIFTAQDFKTKDEIIEFMSQRMHMLGRLNQTYIQSVHDREKCFPTCIGFGIAIPHGKS---EGVKTPTVAFMNLKQEIMWNEE--EEVNLIFLLAVPVNYHLKVLAELSKKLIEEDFRERLKNLGDKKEICNMLTF-- +> +QTILPEKNIILESGCRSKDEVIAYAAELVLGDCSGREKLKQEIWERERLAYTGIGSHIALVHAES---VTVDCPVTACIRLKKYIDWAPGKAKMVKLVFVFAVPK--ETEVLKDMVRKLGKKETVDRLMRAEQSREIIGIFQ--- +> +MSIFSTEMIVLHLDARDKQDALMQLAKRIEAAGQVGDNFMLSLNKREEEFSTAVGYDYAIPHGKS---DAVAVPAVAYAHLTQPILWDEEDEDWVENLFMIAVPADEHIKILTKLATAIMDDDFREHISQAKEPNQVIDIIEK-- +> +--MIDEGLIVLDSALTNKKSIIHYLSEKAKEFGYLKANYIKAVNKREEEFSTAIGYDVSIPHGKS---KEVINPFICFLRTNQPIQWDTNG-NTVELVFMLGIPETFHLKVLAEISKKLLDEGFRNDLLTGSKE-SILDSLYQ-- +> +SSIVNKECIVFDIDTDSKDEVIYTLVKKLKEQNKIKEDFYKNVLAREAIEPTAIGHDIGLPHGRT---NGVIEPAICFGRLKKPLVWSEKTGELGEVILMIAVPENTHMKIISKLARKLMHDDFRDKLLTGDKT-TIYKLLKE-- +> +MNHLSPAFIELNLKLKNKDDAISLLVDKLDENGCLKKKYLDAVLERENLLSTYCGHNIAIPHAVS---KAVKKVSFGFCRT-TNLEWDKKD-ESVQFILILALPDNYHIDLMSQIASLALEEEVREVWVNAKTEEDISKTFHQ-- +> +MTTLTANCIDLNIQGNSVYAILKQLADMAFQNGYVSSIFLQTLLLREKLHSTGFGSGIAVPHGKS---ACIRQPFVLFARKSENVDWKASDGEDVNCWICLGVPQDDQVKIIGTLCRKIIHQDFIDQLKQGDAS-QVLALLNQ-- +> +NDLITKEMILLDLDVNTKGEVIEKLAQVLQVHDRLHGGFIDQVHKREETFPTSLGYNFAIPHGKC---NAVKTAALAFARLNKEVQWSDE--EKAKYVFLIAVSEDTHLKILAQLSRSIMREEFREKLEASTSVHDIINLLSF-- +> +MKYIEKDNIIFNLKIEDKENAIKYLANVFNKNGYLNSKYIEEVNKREETMSTSIGKGIAIPHGKT---NAVNKPGIVVAKLSKPFIWDEVENEEISIIIMFAA-DNTHLKMLADVSMKLMDDDFVEKLKTSKNKEELYKLLRG-- +> +MKLINENLILLDMNLQSKDDIISCIADTLENNQRLCQQYIDDVYSREDEISTAMGSSIAIPHALS---LGVRHTSLVFLRLQNPIQWDND---QVQMVFGIAVRKNEHLRILSNLARKLMDLGFTNALLHSDNPDGCLQLLEE-- +> +MALITEKDIFLSENLSTRNEVLKRLAEISVEAGISDDDVYNAYLEREEVGSTGMINGFSIPHAKS---DSIKKPKILFLRNAQQSDWETLDENPVEVIISFLIPKEEHLRNLATVSKKLMKAENVNILKTTDDKAEIMGVLSA-- +> +---LTLQQIFF-QHFLEKEEVLSEIAILAE--KLGIGNIYDELKKREEEYSTAIGHGLAIPHAKT---DLIHSPAILFFKLEQVIDWS---GDEVCMIIAILTPRI-HLSILSRLSRKLMHREFRERLEAAQTQQEVFDLFRL-- +> +--MINQQLIFIDIDAHTKEEVFEYIAKVAVNNGIVNSIIIEGLHYRESLSTTGMIDGFAIPHAEV---ADLKESVVIIIKLKEEIDWESLDGEKIKFIVAMLVDKKEHLTTLSTIAKILMKQENRDLLHKANNQEEIYTIFEK-- +> +MALINANRILLNKTMKNKNEAIKEMAKLFVEDGVVDDEYLKSLMDREAIAETAVGYEVGLPHGKS---TAVKYPAVAFARLSKDIMWSEEEQETAKFIFMLAIPTNEHINILVNLSKKILDDDFRELLSKSNDVEEIMNAINN-- +> +VSSINPQNILVSIDDTDKKSVIAKLVDALYETGEITKEFIDDVYFREEEGITGIGNGLAIPHGRN---EFVKNSSFAIATLKQSVEWGSIDDEPVKVVILLADSL-GKPIMLDKFMKKLSDEDKLHFLKEATSVSDVISVLDR-- +> +MLTLNKDLIIFCENMNNKERIITKITSLLYRKNYINKDFVKKVIEREKAGSTYIGNNVAIPHGES---KSVKTNCLVILKSRLPINWDGYV---VHVIALFSIHP-IEKENYKRYIQAIGDENFVNKLKNTNDKEKIVMLFEN-- +> +------MIVKYNINCKDKYEVLSSIASIARENNNVRKLYLEGLIKREEQFTTGFGNSVAIPHCKG---EFVQESCIIVMKLENKIDWNSLDNKAVNIIIAFAVAENKYLVDISKIAKHLMDVEFINQIQECNTKDELEKSLLS-- +> +QDYISEELIQLDIQAEMREEIIDRLAELMEKKEVMAEDFLSHVFERERNGTTAIGSEIAIPHGAS---KEVQTPAIAFARLTRPIYWDNG--QPVSHVFLVAAPED----LYASLKERLQDQQAQELLKSAKTPQEIVSALQA-- +> +-HVISPRLVSLNMSFSDKQEAIKKLTELLYANGNINQLFLRDVYLREEEGSTCIGQGVAIPHGKS---EAVVKTAVAIGVAQNTIPWEGAEEQEVNIVILFAVQNTKHILMLQQIAILLADDAFITGLHNVESREEVIELVQ--- +> +-DAIKRKLIKTNMNVTTKDEAFSELVSLLKNEGFVSGGFIKDIYLRESEGQTGIGNYIAIPHGKS---SHVTEPAVVIGINSSEIPWETLDDNGVKVIVLFAVGNQEHLKILSLFARKLGNDQIVEKLINAKNEDDVIEAFS--- +> +-GLITEDNILIDCNVSSKEEAIDKLAELLVELGAVSPGFLKDIYERESRGFTFAGDYLAIPHGWS---KHVVRTAAVVLKTKDSIVWDEKGN-LVKLIIMFVIPEGQGLKMIGQLFSSLGDVEAVKKLLDADTKKEIARLIC--- +> +-DVLPLELIDVSMKATSREEVLEAFADMFEQAGCLSAQFLKDAWWREGEGPTGIGDGIAIPHSKS---EGVSKTSLAVARIPEAVEWPSLDDGPCRAFVMFAVRSQ-EVHLLSKVAVALCHKEVVETLLTSDDPKTIRCALS--- +> +-LQLEKELLKLNMDVTTKEEALLTMIDMFFQNGNIEEVFKQAVYEREAIGETGMENFIAIPHGKS---RTVKYPSVAIARNKKTIYWENIDGNQARLIFLLAVPDTEHLRLLSTLARALAYKEVQDKMLQIENEEDLYDYFS--- +> +-SVLNEQRIDLHLKGQTKDEVLDEMVDLLFKDSVLSEQFLKDVYYREGEGITGIGDGIAIPHGKS---DSVLHTAVAIGRSDHDLEWRSIDDKPVRLIIMLAIKSTVHMKLLSNVATSLCQRDVIEQIFVSEDKQEIIELFE--- +> +-EVLLDEMVILDEPFKDKDDMFNVMTRQFETAGLVSGAFKKALEFRETLGPTYMGNMIAIPHGKC---KEVLTPGIGFCRCREPFIYESGGEGEVKYIFVLAISEDYHLRVLATLAGFLAHDEFLALLEKAESYDDLIKGIK--- +> +-TIINKDLMIINSDANSKEAILEDLCSLLKNKQYIEQQFLEDIYLRESEGITGIGDGIAIPHGKS---GSVGETTVAIATLKNKIAWETLDEEPVEVVILFAVKDTTHIILLQKVATLLARESFINAIKQINNKEELYDLII--- +> +-KILHEDDILIPMQADSKEEAIRQLAEMLKAHEVVMDAFMSDVFLREAEGVTGIGDYIAIPHGKS---KGVKENRIAVGILQEPIYWESIDELPVKVVILFAVCAQSHLSMMAAVAKSLAYDDVKQRLYEAESRQDVMEAIL--- +> +-DILDENIIRIGIDAKDKDDALHKMAGLLYENQYIDEGFVKDVYAREAEGETGLGQGVAIPHGES---KNAQKLGVAIVTLNHPIEWETLDGGKVDTIFLFCVSSRNHMLLLSKIAARLADDDLLKQIRVASSSCEMIALLA--- +> +----MKESIDLNEKYISKEELFKEITKLLHNNNCIENKFLEELLYRESLGSTAIGNEFAIPHATYE--KGANIPCIIVCKLKYSIKWDDAGKFFVKNIILFANPKKKGLKLMASICRTLANEEICIKMSNMKCSKEMANFIY--- +> +-EIIDPNIIKTQLIGTNKDEVLRELASMLLENGYISDGFIQDIYAREAEGQTGIGNYIAIPHGKS---RFVTKVGVAIGVTEHEIPWETLDGKGVKGIILFVVGDQNHLKLLSLFARKLGNDEVVEQLIQAKDAKQVVAAFV--- +> +-EVINENAVAVNVKAQNKEEVFECVCDLLLKDGSITEEFKQDLYIRESQGKTGIGDGIAIPHGKS---LAVKRNCISVLKLEQPIQWETLDGLPAQVFIIFAINQDYFLRLMASVAKKLAQEGTCGKLMGSSTKEDILEAFC--- +> +---MDRKNVIINLDLKNQDDVLDYLSKKACELDIAIESIKTDLINREKVMSTALIEPLAIPHSKS---KNVLKNTIIFLRLNDFIDWSDSK---VN--IIIGIFSGEHINTLANLSRKLIDKEFLKFLQTA-SEDEIYENLK--- +> +-DLMSKEIVMFDVDAKDRNEVINLIADAMDKDGRLIEGYVADVMKREAGSSTAVGFSVATPHSKS---VHVKEPSLAFVRLSHPMKWDDSE--EVELIFQIGVPSDRHLEILAGLFRKVMHDDFREKLFSAKTADEVIELIGA-- +> +-DLINENLIYLNFDAADKEAVLSGLAKIISEEKKLEEGYIGSLHEREETFSTAVGFSFAIPHGKC---KYVKQACLAYARLNNEISWA--E--DAKHIFMIGVSENEHLEILIKLSTAILEDDFREKLNKAETESEVMKLLKD-- +> +-PII-KENILFDVDAKDKADMIEQMVEVFDKEGYLSEQFHKDVLAREEVFSTYIGFGIGIPHGKS---SGAIDAGLCVAKPKNPVVWAD----DVDFIIMIAVSDELHLQLLSKLSRLMMHEDFRNELKNGS-KEEVYETLIK-- +> +-DLINQHLIKINTTLNTKSEIFETVCKLLEADNRLLQLFLNDLYEREGAGATAPGYSFAIPHAKS---KGVKTASLVFIHLENEIGWT--K--SVKYIFAIAVPYDEHLNILAMLARKMMNEDFRKELNAAKTKEEYYRLLTA-- +> +-ALVD----FTNQTFQDKEEVIRYIAEMVWENKKIEQAYINAVLKREQTASTEMGDQIAIPHGES---DTVRECFVAVLKLAKPVVWD-----QVALVFNIGISKKEHIEILARLCTNLMVEEDREKLYDAKNREELCDVLKS-- +> +SQFCRSELVNFSLESTTKKEVIREMVKLAAQSELVLEKLYQDTMEREKLLSTGIGFGVAFPHART---EAVKGLVIAFGRSDAGIDFDALDGAFVHMLFLVAVPKTTHITVIAQLSLILKEPVNREKLMNAVFPQEVIDLLNT-- +> +RTVLTTDTVDLHLKGTTKEAIIDEMLELLVKAGKVTAAARECVLDRERKMSTGMKHGIAIPHGKT---DTVSDLVACIGISDNPVDFDSLDQEPCRIFIMTLSPVGPHLQFLAEVSLLFKSPEKRQLILETQDKAEVIRILTE-- +> +PPALLQRERIINLAAEDKSKAIKELVDLLARHPAVTDELFRAVQQRERDMSTAMGCGCAMPHAKV---ASVRDFIMAVGLSRKGIPFEADDGTPAHIVVLIAGPLRRYLKILGQVSAVLADDARREGILTAMTADAVYEAFKD-- +> +KMIIHESLIDLNVLSKDKDEIIGDLACKAEKLGRISVGYLQAVFAREELFSTAIGYGIAIPYGKS---SCVKKPFIAFAKSNKAFTWDSRSEQKVRFIFLIGVPEELHLKIAANISRSLMNDSYRERLVQATSTRKIVAIFGE-- +> +VEVIRPDTVDLDKGITCKEEAIHYLAGLLNEAGLINDAYIQSVYERESLGPTYMENFIAIPHGKC---AAVREAGIAFGRSPEGFEYLTQDGGLAKLVFLLAIPEDAYIAVLAQLARLLVHDEFRAKLMEAKCYQDVFEAIAE-- +> +TGYLNRKNIFLKFSAADKHDAIAKLVGMLSTDDAIAEEYLASVFEREELGTTGLGDSVAMPHGKC---SAVSRMSIALAKLEKPLDFESVDKKPVDYIFLIASPLTLYIKVMASIIRSVKIHKICEKMNVLDSAEEIYEMLLK-- +> +IDILKQEYIKIPLFSTSKEEVVRELIDILTPFSIYEDLVYSAIMAREAIMTTGVGKGVAIPHCKK---NECKEFAIALGIHPQGVDYQSIDGKPAQIFFLLIGPEGMHIRLLSRISRLISKDMLREKLLSCSSASEAYHLIKT-- +> +VLRYLREDRILLHMAKKKAEGLRELAALVEDSAEIPRKFLSAVFQKESRFGSGVGEGVALPHYRD---EKVKEPVICMGVSEKGIDWGEK--EQVHILVLVAWPY-NYLKTVAEIARLLRLAPVREKIRNAGGPSEVLAAMQT-- +> +MKIIEKNLIHLDLAGTDKKEFLNSLCECLHREGVVDEEFFQAIWEREESFSTGIGRNIAIPHGKS---SVVKELKILVGLIPAGIEYESLDSEPVNLIFMFAVPPDRYRVLLGKISAFTREDANRLELLASKTKEEILTIMSR-- +> +LQELLKKSNFLEIEVKDKFEVLKTLVEDAKLDEYLKKEFLKKLIERERLISTGIGYKVAVPHAHS---EEVKDYFIILGYSKEGVDFDSIDGLPVHLFILIGTPG-TYLKILSEISRMIKNTKDV---STLDSKERIIQVFSE-- +> +REVIDENTVNLELEANDRDSVIRELAKMLNHNGLIQECFIQSVLEREKICSTYSTSELAVPHGIS---PSVRKAGLCFGRLTSAIDWDGDQETPVRYVFLIAIPQNRHLEMISSIAVSALQEDNLEKWGKVKD-------AEE-- +> +LCRLIGKNGICQLSKTNKSQAILELISHARQFANKPDDFYCEVMRKELLQSTGLGKGIAVAHGTC---QGIDQVYVALGISQEGIEYDAIDSQPVHLLFLVANPP-EYLSALSTLVRLLRNDSFREKIMHCVTAEQVYLLFKQ-- +> +SDFVCFEATIAELQSSRRDDVIIELVSSLEKAGQLKEEIIKAVIKRENEASTGMGKGIALPHVKH---PSVKDVIAAIGKSSIGIDFSALDKQPVYLVILLISPVDKHLQAMENIFKVLQQEKFRKFLRQSRNAEDIEDLLRE-- +> +ADYIKVDTINLNLESKNKSSIIKELYNNLKKTNLIKELGLNDIFARQEMGSTGIGRKIALPHAKT---KAVDELIATFGISRNGIDYESLDNENVNIFFMFLCPEQEYLKVLARISRLIRKDRFIDNLLKAGSNKEIIEIIRD-- +> +HNLLTQDMIILELESENAEGILREMVRFLR-KDIVSKELYEKLVQREKLGSTAIGEGIAIPHCKI---KRVKNPVVMLAISKKSVDFCSLDGKPSNIFFMVVSSPSINLQILAAIAHLVRKSGSLAKKILAKNISAVMDVIRE-- +> +EDILNKQRTCVFLSGQNKNDIIAELIGLMVKDGLISRELLDSAMEREGLMSTGIGKGVAIPHGRA---KGLKKMAGAFGLCRSKIDFGSLDGQPVQIFFFIATPQADHVKALALVSRLLNREEIRARLLAADDPQKVMDIFTE-- +> +SEMLKTNAINLRLKSRTKRDTLVEMVELLETGHGFNGEILDRVMRREAMMTTGIGNGVAIPHGKA---RSVDRMAAACGVAPEGIDFESEDGQPTYLFVLFVSPETLHVRVLANISRLLKEETVRKALREAKSPEAFLTVLQS-- +> +STKIKKSAILLDMKATNKDEALKELVDLLCSAYSLDDEILEAIRKREKKQSTGIGMGLALPHAKT---AAVDKLYVAFGRSNTGLDFDCPTGEKAHLFFILVSPLGPHIKALAGISRMIKHEDFRTALMTVKNEDEFIEIVKE-- +> +SERFVDNCILINSSSETKEAILNELVDTLCSAYKLEDEIFEAIWSREQSRSTGIGCGLAVPHAKI---DYVDRMCMVAATIEKGLDFQSFDGEPVYLLILIVSPGGPHLKALSSVSRLLADGNVRKDLIASKTPAEFLSILRA-- +> +SERFTDNSVIINSQSSTKEQILNELVDALCASYKLEDEIFDAVWKREQTRSTGIGCGLAVPHAKI---DYVDRMCMVAATVEKGIDFDAMDNEPVHLLILIVSPGGPHLKALSSVSRILANAEVRKDLIEAKTQADFLEIFGR-- +> +TEVMNENLMILDLESENKDGTINEMINLLEKENLLNAEYLKDVLKREKASSTNLVEGLAMPHAKS---KGVKNPAVVFARSINGISWDHEE-KNVKVVFLIAVPEDDHLIILSTLAKCFMHDNFFDNLVEAKTRTGIINVIED-- +> +ADILQPDRMKIPLVAADRRGAIDELVDVLADRGDVSEGIKEAVWQREQIRTTGIGHGIAIPHAKS---ACCEKLVLAVGVPDEPIDFDAVDGQPVRVIFLLISAVGPHIQALATISRILTDSNLRASITEVASAQQLHKLLVE-- +> +SEILLEKCVVADIKGKTKREIITELVEALEKARLIEEAVVNVVMEREKLGSTGIGNGVAVPHGKL---KNISNIICALGRSPNGVDFDAVDRGPVHIFFLVLAPESLHLKILSRITKILRDQSLRKKVIKLSNTHDIYTSILE-- +> +TDLLHPDCIQVPLVCKNKQDAIFQLIDVLAQKHHLTQQLKDAVWERENTRTTGMGFNIAIPHGKT---SSCDKLIMGVGIPEEPLEFNSVDGQPVKLILLLISPAKEHIQVLSAVSRMLVVEDIREAFFRATAPSEVYELLQK-- +> +EEFLSEDLINLDFNPVNKEDALSKMVQMFKKENKIKTDFLNKIFKREKEGSTGFGRQIAVPHGKS---KTVKELSLAVARVKNGLKYNSLDGQKVKLIFMVADYEPQYLKLVSTLVSLLRDNNFRTKLIEAKNKNEFIDLFRK-- +> +CKRLSTDCILLDLHEQDKEQIIRKLVSALHEAHHLSEKLLVDIMAREELASTCLGSGCAVPHAHS---ETLSTSLLAAARITPPADLETPDGHPISLVFLLVGPSVVHLKLLSKLARLLHDEVFRHQLLASDCAEAFHALICK-- +> +SEILNEKCIILNSELNDKDEIIEKLVELATKSGNITSKVLEEVFVRENLMSTGIGNNIAIPHTKS---EDIKELTAAMITLSKPVNFDSLDGKKVSIVFLILSNSGLHIKALSKISKILNNRSFFGDILNVSKNAEVIELFDN-- +> +TQLITADRIVNLNKEATKEAAIKTLVRCLS-TKFVSKELAKAISDRERILSTGIGQGIAIPHAKI---PTVSGFVAALGISKNGVPFDSLDGKPANVIVMIAGPEEEYLRILARFTSILKPEETRNRIIEAKKGAQVMGILQE-- +> +SSYLSLDLIKLHLNANTKEEMLKEMALLVK--DKVTDKFYEALLDRESAGSTAMENGLCIPHTRN---SYVKEFCIAVGTKEEGIDCSSIDGKKSTVFFLIISNDLEHLDALVKISRVVNDEIATMVLSSTKSKEGFIELIKK-- +> +MDLIG-SNINLHSKARTKEEAILELCDMLEKSGYIRKLFHDDVYKREALGLTGMENGIAIPHGES---SAALKAGIAVLKTSNPLDWESLDGKPITLVFLLVVPTTAYIKMLGHLAAALAYSDIQKRLSEESDSDK-FKEILE-- +> +TDFITPDCIVHHLQATDAQGAITELVHHLAATGRIDETIIEAVWAREQQRSTGIGDGIAVPHGRC---EHMDQIVAAIGTADPAIDFQASDGKAVNLVVLLVSPTTLHVQALGAISRRLGHAEIRRRLRNCPDAGCVYDVLCR-- +> +VSMIDERLVKFDFHVLDKNDAISKIGQLMFEAGKINDMYVNGVFEREKEHSTGIGMGIAIPHCKS---DCVREVAFTLIKLCDSIEWDAFDDQRVEYIIMLAAPNNLHLKMLSQLAVCLTDDDFRKSLLNSKTVDEVKQCLNN-- +> +MSKLVNVKCSFEMKATSKEEAIISLVDVVSKEGYLKNQFLEDVLKREETLSTYIGHGIGLPHSQS---IGVKDSCITIGKLDTSIEWTEE-GEKVDLIFLISVAKNLHLKILSKLARLLMHESFRNQIRESDEQT-VYNLIKE-- +> +NKIIREERINLNLEATTKAEAIDELAEILVKTNSVSAGFIRDVYAREEIGETGMGGYIAIPHGKS---KYVENTAIAIGRTKEILEWESLDGKGVKFILLFAVPETVHIKLLSQVASTLGDEEVCARLLTVESADDILEIMTN-- +> +SNLTNENLINLQLKGKDKIEIIKELASLMEKENKLIAQYLQDVYKREDEYSTAFERGIAIPHGKS---HGVRESCIAIGK-CNKVKWSHEDNCPVEIVILMAVPKDEHLAILSKLAEMLMEDEFIEELKKAATSNEVLNMLKN-- +> +LEYFNSKLITYINGKHTKEEVLKILVDLIRETDVLKQHFYENIMAREELGSTGIGQGIAIPHARS---EKIEEIVVAVGLVENKIDFNSPDGEGVNLILLVGAPKREYLSLVSELMRTFRNKKLREAVTCASNYQELLEAIAE-- +> +REILTEESIILDLKSTTKEGIIQELVDKLYDTGSITSKFIKALKHREKIGSTSIGYQMAMPHGKT---KYVKKASIVIGKSKKGVDWPSIDGLPVKVIIMFAMPQNEDMILISKIAYILGGKNIGERLLNAHTKKEILDIFYE-- +> +MGKLINKNCIVFDIRGDKKDVIHRLAVELGKAGTITEEFYKDVLAREAISPTFVGFDMGLPHGKT---DHVLEASVCFGRTAEPVIWNEESGETADLIILIACPLDTHMKILANLSRKLMHEEFRESLRNSDEEQ-VYQILTE-- +> +RDILSEESIILDLKSTTKEGIIQELVDKLYDEGSITSKFIKALKHREKIGSTSIGYQMAMPHGKT---KYVKKASVVIGKSREGVDWPSIDGLPVKIIIMFSMPQNEDIILISKISYILGGKDISKKLLNAHTKKEILDVLYE-- +> +MSTINPNNISLHLECSDQEALLQKMTHWLFQSHAITAGFLEDVDYREMLGMTGIGNEVAVPHGSN---CVAY-PTVAIATLQAPIAWKSIDDAPVRLVLLFAEPDDAHNTLLTKMIRKLSNDETLYAVKQAATVDEIVNALKE-- +> +LI------VFSDTEYASKDAVIEGMA--ELVANKVDEGFANAVKEREAAFCTYIDHGVAIPHGKT---DIVKSPFVIYQRLGKGVTWGEDG-EVATHVFMIGVPENLHLRILAELSKGLVREAFRDRLLGTDSKEEVFEILKD-- +> +SDYLKEENIKMNLVAKNKEKAIKTLLEFNS-----LESILKEIMKREELESTGFGNGIAVPHARI---DGIPSITILVGVSKKGIEFDSLDGKPANLIFLILAPKKLYIYILAKLIKVLEEEKNLTELVNIDTPQSFIEKFRS-- +> +MALINGESINLNLQGSTKENILKEFAALGYQVGKVSEGFYQGLLDRESEVTTGFGYGVAIPHAKT---KYANEVGILFGRTNNQVEWQALDDKPVNTFICFIAPENEHLKLLAKISRKLMHQDFVAVLKNG-TKEQILQALET-- +> +LI------LFLDKEYKDKKELLTDLS--KAVDSKVTEDYEKAVKERENTISTFIGYETAIPHAKT---DAVKNPFVAYAKLSHAIDWDGNG-EMVKHIFMIGVPKNLHMRIISELSKNIMRNAWRESFMNAASADEALAILKL-- +> +MDILNNQTVFLNVEGSTKEAILQAVTQQLETSGYVKKHAYNDIMKREAEISTGFVSGIAIPHTQS---EAVEKTSISIIKPVNSLSWETMDDSDVDLIFLICVPLDEHLKILASLAEMLMDEDVIDALHQIENEDEIVDYIRR-- +> +-MIIHESLIELHMKSKSKTEIIETLAHKAKELGYISEGYLQDVFALDESSPISFGYGIAIPYGKS---RYVLTPFIAFARSEEAFTWDHRVDHEARLIFLIGVPEDFDVKMLTHMIGGLTNESFRRRLLQTSDAAEVVELFKE-- +> +KKSLVAKAISLDLPSDKNEAIKVAIKALTK---LSLDEVFEAVMAREKALSTAIGLGVAIPHAKI---KSLKKFAYSIFCSEDPINFQAPDKTPVRIIVLLLSPEKEHVTLLAEISRRLKFSHVRQAILEAKTPKKVAEAFLQ-- +> +ENFINKDNIILDLETENKIEIINKMINTIS-NEKLAEKFFEDVLKREKMENTVVGFKVAIPHGKS---EFINSPQIVFAKLKKEIFWGDPD-EKVKYIFLLGVPS-EHIKILMKLSKKILEEKFREKLEITDEKEELLKIIIE-- +> +MLQIPESNIILNLKGTDKATVMKELLETI---QHIGEGILKAILARNKIMSQAPGRGVAILRYLG---TYARTTSLAVGIKREGINLDALDGRPVYIFFLLV-SN-KYVDILAGLLRLIQQPTIRLNLLRAHSKSQIRKILET-- +> +-------------------MGIKELVDALDMDGRLACCVEDAVWKRESVYSTGLGYGVAIPHCQS---NDIYNDSIGVVRLKKPVDWDAIDGKPVDLIFLLTVRQENHMKFFASLARKLVNDVFLKQVRACTATDEML-DLLN-- +> +-DVLNESLVEPGYRADSLEEVVEELLRLLDATGKVLELARRDLRENQQHLTAGMQHGIAIPHAKT---AAVKELLAAVVVTERPLDCQSVDGSLSQIFIMTLSPHGPHIRFLSEIGRLLKHRRVRRKLLEARDSGELLAVLQRA- +> +-QYLVPERVWIKVEVANRNDLLAYLARQTAGCALVPQEFFKLLIHREEEMSTGVGRGLAVPHADP---PAMKSTFLAAATLASPIDYQSFDRVSVDVVFMIFGCPSLHLRLLARISRIARLPGFLDRLRQVQTTPDFLRVVEEA- +> +-DLMDPKGILLYANIDNQADALGIMVELQESSGVITTAYYNAVCQRETFGTTAIGNGIALPHAGN---AGVSAPGISALTLRHGVDWGAPDGRAVDLIFMIAVPPSLHLQILARLVNLLEYGTLVDALRHASSPARFLELIQRA- +> +-TVFTPSCAAVEVRAATKADAITALVDLLAAAGKAPAGLLAAVMAREALAPTGLGEDCAIPHAQT---DTVTETSIAAIRLAEPLDFGAPDGSSARLVFIIVGPKALHLRYLSRLARVLGDPDFHDAAFAASDAAAFVAAILAT- +> +-DLLDKQCILLDMDCQDLQQILKSLLTTISEAHPQQAPMMEKVLTNPGFSTVCMGFGCAISHARC---TEMKKTFIAVARLSPPLDLGADDKLPVALFFLLVGPQLFHIKILSRIARLLHASEFRKGLLQAKTSEDFHQLICNK- +> +-TLFSSSNILVRPGLSEKKAVLQAMIRQLEKSGTVTDQLLADVMEREKLAPTALGHGCAAPHAYS---DAITKTEITAAVLDKGIDFGASDGEPATLIFLMAGPKRLHLSMLSRLARLLHNQKMRNALKQVQNSGDFMELMSQW- +> +-DVIVKQCILLKKDVQSKEDALHMLADCLNEEAYITSAFLKDIHKREEEFCTYVGHETAIPHAIS---ACVSKAGIAFLRSDKAFQYGSSDET-VKLLFMLAIPKEQHLRMLSALATKLMHKEFREQLLHAKSISDVYEILMLH- +> +SDLFTEDFILLDVDINSKDELFKAAAEHLYSKNIVNELFIKALYDRESIGETGVGDGFAIPHAKS---EAVNKPAVLYIKSNRKIEYESLDDLPIDNFFMLVVPENEHINLLSSVACLLLEDEFKAKLENVKSKLEIIDLVNKY- +> +GMDFTEENILLDVVVASQSELFKSVARYAEKLGFVKEKVYEAFVERESEYSTGLQDGFAIPHAKS---PYVLAPTVLFIRLENELEWETFDESRVKNIFALLVPETLHLEMLSRLATALMEDEFISQVQKNTNKDQLVTVIKNE- +> +SEIIKQEYIHLHCPAVTKAEVLQTASRWAAEAEIIAALFLKGLWDREAEFSTGVGDGIAIPHCRL---ESIRQPSVFFAHLENPVRWSP--EEEVDLILVLAVPSNTHIRLLSQLARKLVDEVFVSQLRELDQPAAIYALFNDI- +> +GAILNEKTFFLDIAFNDKDEMFVQLTRWYFEAGLITEVFKQALYEREALGSTYMGNEIALPHAKS---SVVKRPAVLFCRMREPFLYESSGETLVRFIFMLAVSEEAYIQMLASLAGLLANDEFLQKLRSLETLQEFLKYARDL- +> +SQLILEDLILFDDSIRSKKSLFECLGNMLESAGRIKKKIIRAFFKREAEVSTGIEDGFGIPHAKS---KYVLVPTVCFIHSGKITEYLGVDGIPIEYVFAIVVP-ASHLEILSMLSRQLVDSSFRKQIKEATSRKKIMTILKNI- +> +IDLMMSDLIIFNESISSKDELFEEIGRILEENQRVTRKVIKDLYKRELETSTGIEDGFGIPHAKS---KAVLKPTVCFAHTGKMDNYVGLDEKPIECVFAIIVP-EIHLEILSGLSRKLMDLEFRKQLKSATNAAEILEIINKE- +> +YMVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTEALLKDLLKRENEFPTGIKDGFAIPHTKS---VNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAPKNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNK- +> +ENVINRSCINLHMKGRDKKEVIEEMAEMFDRAGVLVAGYIKAVYERESEGPTGIGDQVAIPHGKT---AAVGKTAMAVGRLDKGIEWETLGEGTTRAFVMFAVNDSELVSLLSQVAIALCDEKVIETLLNTESEAEIFTLFNRK- +> +SSMIDTNCILFDSTIQLKKDLFSRLATILEKSGYISKRFIKDLEKREKESPTGMEDGFGIPHAKS---KTVKSPVIVFAHTGKIVDYIALDGSQVDCVFMLAVP-DIHLDILSYLARQLMNDDFKLELKQASNASDIQSLLMNK- +> +SKIFNESSIILGTTLKTKAEVFEKLASYFYKNNYCDEMMIQEFWNREAEGSTAFINGIGIPHAKA---EKINYPGICILKNNTGIEWDSLDGEDTSLFIALAIPKSIHLKMLSSVARKLADAEFKNNLLAAKSKKQIYELISSV- +> +MTIIHKENIFLQQPLDSQEEVFMFLAKQTFCLGIAHKEVYQKLLEREKEGTTGIMSGFAIPHAKS---QAINEPSLIIITLDKGIEWNSLDKQSVDFIFALFIPSTTHLKLLSLIARSLMRKEITEQLRVAKSKTEIATILIKE- +> +NNVISEESILLDIEASSKDEVFDIMSNNLYKLNRISEEFIKSLYEREALGETGVEMGLAIPHGKS---KFVLINSLSVARLNNPIEWETLDDCLVSIVVMFAVYQDEHLDLLAKVAGNLVEEDTIEFLKTSNDKIAIINK---L- +> +-MEFRNENILLDVAVKDKLALFDYIADYAVTHQIVADALVEAFLKREREVSTGLQDSFAIPHAKA---AFINEPIVLFLKLSQPIEWETFDDKPVANVFALLVPEMVHLQMISQIATSLMEEAFTDIIKHTNDVTLLTKTISSA- +> +KEMIDPKLILFDERINTKEELFDQAARLFNSVGIVEKKYKKDLFIRENQTSTGIEDSFGIPHAKS---QAVTRPAIAFIKSGPISDYKAMDGTTVEYSFLIAAP-DEHLMILSSLARLLMHEEFRNKLKEAVTPKDIIDIIKTN- +> +KEFLIEKQIIV-TDLTTKQDFFKTIADLAFENNILSEEVILGLNERESKGSTGLLDGFAIPHAQT---PSIKKAAVVIVKSTNKVGWESLDGEPINTAICLLVPSTTHIDFLTEISKLLMDDDFRANLNKLNDSHSIYEAFLSQ- +> +NELLKPDYIIFNVEASTKGEAFRAISKIAFEKNITTQDFENGLWARENLDSTGFGHNLAIPHAKV---NSVTSAALIIVKFTNDIEWESLDDEPVKMAFVIAVPNNHHISILSQIARRLMHDEFTEALLLAKTPQEVEALVKNN- +> +MNLFEIDHIHLDLEVSSKDELFDFIANALKALGRITADFKKALEKRESEISTGLGEGLGMPHTLD---TSVMFPTMLYIRLKNEIDYQAIDGLPVKEIYAIAMPNKEHLELISKIATIYIDETSKQEIRALDTKESIHSFISKN- +> +--MILEKTVFLGETLHSKDEIFSFIAKQAYKLEIVHQVAVSDLKKREAEVSTGLQDGFAIPHCRT---ENVKKTAILFIRLDNEIKWETFDGKDVKNVFCILVPGAIHLQLISKIAVNLLEDEFKQKIATAKSTKEIVELINFE- +> +MEVFTKDNIYLDVHIDQKEDLLREIAEKICLLGYASEKVHKGLLDREKEFETALGEGFAIPHTKS---EYIKTPGIMIMKTTEPLSWSE--EENADVFIVLFTPENTHLKMLASLSRRLMNQDFKRILHESMDKDEIYNAVYEA- +> +MDIFKKDYIFLDIGLKDKENSIDFIAGKAVELSISNDQTKKDLWSRERAFNTAIDETIAIPHTKS---ESINLPAIFIIKSKNIIDWGG--K-NIKLIISFLTPENIHLTMLSKISRKLVDDKFKTTLNESDDINLIYELIMSA- +> +---IRKELVFVDEEVDSQSEAIEKLVHQAVQLQVIEESFLKAIYHREEEFSTAVGFGVAIPHGMS---DTVREAFVGFMKPKHTILWGNE-QKEVDLLFMIGVPEVIHLKLISQISKNLMKQEFREKLLACKNNDEAFQYLEK-- +> +---AKELTIFTDKVYHDKYEAIEDIAHL--PNEFVNDEYAKAVIARENVIATYIGYGIAIPHAIS---AAVNQAFVIYVKFLNGCPWANEDEDRVDHMMMIGVPATQHLKILAELSKNLMHEDFREKFLNTKSPEESYELLKS-- +> +---DEQLT-FVNKTFKDKLDAIDFLIQEAKAAGKITETYKKSVLQREAEFSTAVGYEVAIPHGAS---DDVTESFVAVSTIENPILWGE---ESVRMIFMIGVPEKEHLQILAWLSRNLMHDDFRSNIINATTETQLFECLSR-- +> +---IEKELIFLDDELTSRDEIVRKMSENVRKLGMITNAYMEAVLKREEKIPTTVGLNVSIPHGKS---EAVQHPFVTFMRTKNPIVWDERSDEKVKLIFMIGVPIKLHIKILAQISKNLIDETFRNRLLEASSTEEVYRLLKQ-- +> +---VPQAMILLDEEVENRDAAIHHLVSQAKEANLVNKQMEEAVLAREAEVSTAVGYQVAIPHGKS---EAVNRPFIGFLRLKDTMLWNDSD--EVKLIFLIGVPENIHLRFIAQLSKNLLNENFRAFISKESSQDKLYEFFKE-- +> +---VAEEMIFVNTSFNSQKDLFEFIADTAFGLGRTSKSVVDGFYHREGEYSTAMNDGIAIPHCRT---ESILDASVIIIRNSEKVIWTEDE--ECDLFFALLVPEQMHIRILAQVAQLLLEDEFVAQVRQANDPSYIFDLVKE-- +> +---IRKDMIFVDVSATNRDQVISKLSETAKALDLVDEDFIQAVMQREEEFPTSIGFKVAIPHGKT---KTVKEPFIGFCRTEQPFIWEQEGNKEVSLIFLIGVPQTLHLVILSQISRMLMNEDFRRKLSESKQKEDIYALLLD-- +> +---IHKEMVFLKQALSTKDDVIELLSDQAIKLDLINKDFKEAVYKREEMASTSIGYQIAIPHGIS---HTVNRAFIGFVQIKDAFHWNHDEKQSVQLIFLIGVPQNIHLKFISLLSRRLLDDNFRKQLIEVEDVEDAYRALNA-- +> +---YSERLIAVNLEADSKDSAIEQLICMLDKENRINSEFRDSIYERENESTTEVGEYTAIPHGRS---ETVIENSVCIATLKKPVIWNFETKEEIDIIFMLAVKKDTHIEILSELASKIMEEDFISNIKNSDSKNEIYKIITE-- +> +---FSKNRILLT-NTIEKDEMIDIMCQKLYEDQLITEIFKKEIYLREKEYPTYVGHGIAIPHALS---NTVQSAGVCFMKVAEGVNYEGGG--KAHLIFMLAAPEQTHLKMLSTISANLMHEENRIKLLEADTVADIYNVLSG-- +> +---EPEIVKVSSTRFETKEEIITYLSQKAGHAKKIKKSYVDAVLDRESTASTAVGFGIAIPHGES---DAVTETFVACLHLLHPVQWDH---DEVDLVFMIGVPLKEHLRILAMLSRHLMKEAFRKELRKIRTDQEFYECIKF-- +> +SDFVQASHVFLDNPAKNVDEALEFLSRKAVELGVADRAVLDAFKAREAEGTTGMMSGFAIPHAKS---AAVKEATVMVVKFAGDVEWESMDDKPIVVAIALLVPGTTHLQLLSKVAVMLMDEGFRNDVLGATDEASIAERINS-- +> +RELLQKKYIYLDVDLHTREEVFHFISKESFKLGLAEVAVGRSLAEREEQSSTGVLDGIAIPHAIS---ADIKVPAILFIRAKEGVDWQTIDNSQVKQVITMLVPKQEHLETLADLSGELVDEEQRKKLAACLSVDEVYDFLNQ-- +> +RPSFQVDHVIRDPDSTTRDQALRFIAQQMHQAGYVGDAFFSALVARETQDTTGFKDQIATPHAKS---KQVKHAGIWVVHFANEIPWETMDERPVKTAVAFAIPAETAMAPLIAISRANMKPTFREVLNHGDTVSIV-AAIED-- +> +SKFVSSDQILVQVDVDSREKALELISQKGVELGFGDKSIYDAFIAREEQGATGMEHGFAVPHAKC---DVINKAGILLLKLVKPVEWPSFDDQPVDVALALLVPGTTHLKLLSKAAVMLMDEKFRDAVRATDDTQALADLINA-- +> +WNCLHTKRIFLDVPLPDKDAVLQFVAEAFASRGIVKDSLYDGLKAREDTMSTGIGRGIGLPHAMS---NDTHDAAVLLVRCSEPVDFESLDAVPVKVIVALVVPEDLHLQMLASLARLCQYPGFFKTVQDAKDPKALFDSIKQ-- +> +SKIIQADFIQLQATETSQLGVFRKIAAIAMEKGIASEEVVTGLKEREAQSTTGFQDGFAIPHTQC---AGILKPAIVIVRTETGIEWESFDDQPAFFFIALLIPKSTHLQALSSLSRVLMDDNKRQELLEAQTNEKLAALVEK-- +> +TSILDIQHITFDSSVTTKDEALQFIADFAKEKEIVKKAYYKGLKKREQEVTTGFKSSIAIPHCKH---KTVKKPALMLVKFTNPIEWESMDHQPVHMTFALAIPEQEHLTLLSTISRALIDEAFTKSIMEAATAEELHAIIQN-- +> +TEIFKQDYIFLKEHLKTRDEAFEFIAKQAVTLKFADDAILKALYKRENEASTGMQDGIAIPHAIS---VHLQQPAVLFVRSTTAIDWPTFDDQPVDQIIAMLVPKQAHLEILANFASALVEDEERQALLKSQTVSEVYNVLTT-- +> +KEIFNINHVFTDVIANSKKQAFEIIALKFYLLGFTTNKALKGLKKREKEGSTGFNDGIAIPHAKI---KEITKPGVFVFKFKNGVEWDSIDNSLVTIAIALAIPENDHLKILSSIARKLVDDDFRKDLNKANNVDQLYQLISK-- +> +TALIKKEHIYLQETLSSQAEAFDRVAQVAYESGAAQQAVIHGLAQREAESTTGFIEGFAIPHAKL---KDITEASVIIIQNQMGIEWNALDQNPVTFIIALLIPDSTHLNLLSSVSRMLVHEDARQQLIKASSPDDILNTFSS-- +> +IDLYNPRMVRVGLPGQTKAEVFRSMATLFVETGKVTERFVEDLQTRERSISTGVGRGLAIPHGKS---EAVSTATYAIATLRDPFLWDEDDEETTKLVVMLGVPATTHLRLLSEFATALMDDEFRAELINAEDEADIRSALAS-- +> +--MMENLFVYTNVAANTCEAVFAFLSTKIVEVGKATQAVEIGLKQREAEGTTGMMDGFAIPHAKS---ESIEEPTIIILKLTNAVAWDSLDGQPIKYVIALFIPATSHLALLSQMARMLMDEGFKQAFITASTQEEIVGLIDS-- +> +SNILAPENISLNETAASQADVFQLIAEKAGELGITAGAVVTGLAEREKQGTTGLMDGIAIPHAKS---ASITDAALVVVRLRESVEWESLDGNPISMAISLLIPETTHLKLLSQVARTLIKPAVRAQLLAAETPEAVVEILGQ-- +> +TNIFNKEYVFLNVDAKSKVEVLKFISKKAKELNLAESLVYEGLMSREEQFTTNLGESIAIPHTKN---DAIENPAVVVLKFNEDVVWNEG-EDKVKLAISLLMPGNIHLKLLSSLSRKLINKDFKDSLLKSDNVEEISNLINE-- +> +PDFIQESNIFPEQSLADRDGVLRFISDRAADLGITDDGTYEAFQYRESLDMTGMLEGFAIPHAKC---ACIKRAAVIMVKNDRPVAWPSFDDVDCDIFIALLVPETTHIKLLSKTAVLLTKDEFRKKVRETDDSAEIARMINE-- +> +-MLLQENQIFLDIELSNRDDVLDLISSKAQELGVIEETLVQDLISRENKYSTAFQEGIAIPHAKS---ETVNKAALFFIKMNQKIDWNSPDQFKVRFIFAILVPTTRHLQILSALAGNLMEEDFQESLSTIETKEDVMNLLKS-- +> +SEVFTKNHIKINLDLKDKDAYLRYIAKLSIELGIGKQGVYEGLVSREKEFATNLGDGIAIPHTKS---DYIIKPAILILKPQKEVSWGNVAEEDVRIIISILSFNNTHLELLASLARKLVDEKFKNALVNSVDEEEIFFLIEQ-- +> +MVLVSAQHVFIEVALDTKTSALQFLAESARKLQLTTSAVLTSFNDREKEGSTGMMDGFAIPHAKN---PTIKEASVLIVKAKKPIEWDSLDGQLTEVIIALLIPETIHLKLLSKVARLLMKTEFKQQLKHLESSAEIATYVNQ-- +> +KSVFDRHHIHFDTEAKTQKEAFRVIAHEAFTAGFVKNAYYEGMCAREEEATTGFQDGIAIPHSKN---ETCIKPGIFLVKFKHAIEWNALDGKPVQVALGLTIPEEQHLRILSKLARKMISEEFRTALKTGTDVDALYEVIAA-- +> +MGIDIQKSIIIDVSALTQQEVFNLISKEAVSNGYADTLLLKALNEREAEGTTGMMDGFAIPHAKS---KTIKKPAMVIFKLTEGVEWNSMDGKKIEFVISLMIPETTHLQLLSKVARLLMKNDVKQLLKNANSASEIDSIFTR-- +> +IKIIIPEQIVFDVDASSQKEVFSKIADLAKQQNFIHKKLIKAFKKREKESTTGFGDGFAIPHART---KDILKPGVFFIRLNQGVEWNALDGNPVKIVIALIVPTDTHLDLLSKIAQKIVKPDIQKVLSDSKDPKQVIKALIA-- +> +MELISKELIDLNQSCSSKQEVFEQAAAIAFQHGRITEKVVEGLFQREAQTSTGMIDGFAIPHTQN---EAVKVPSIIILRNAADIEWETMDDSNVRFVLAILIPKNLHLKILSAISRKLMDERYRKFLLAAESRTEVVDLLEG-- +> +--MLNKQLVFCNKNLINQKEVFEFLAEITTKNQIAKNQIFDSLKKRELEGTTGLMDGFAIPHVNS---IDILEPTIVIIKLQKGIEWDSLDGKLTNYIISFFIPKNKHLKFMANIARMLMLSDFKEEFKRAKYKKEIIEVIEK-- +> +---------MVGCALTSRDGALHALSARAVELGIAEQALVEAFLQRENEGTTGMMDGFAIPHAKA---STIKRRAVLVAKSNSAISWETMDGEPVSVIVALLVPETDHLRMLANMAEALMDSRFRSMLRRSDDPREIAAEVNR-- +> +--NFTEENILLNVERATKEELLQFISEYALEIGVATKEVMEDFLQREKEVSTGFTHGIAIPHAKS---VAVTKCFVLYIRTKEGIDWGTLDESAVTDVFAVFVPKALHLKVISSLAEELIEPEFIEVIRCLNTSSELANYLNK-- +> +--EFTLDNILLNCHAKEKKELLSIIADHAERIGVSTRALFTDFIAREEEGMTGLQDGFAIPHAKS---SAVNQVTVFYVRNESLFDWETFDEQGVKHIFALLVPITKHIEMLSKLATALMEDHFKQKVSNSMNEQELADVIEQ-- +> +--NFSQENVFLNVSESSINSLLKYISEVAVITGYTTKALNKSFIDREKEFSTGLEDGFAIPHAKT---AAVKKAGFLYFRLANPLKWQTYDDQPVTDVFALMVPPNEHLKMLANLSTALLEHDFKKELRRMTNRNEIANFINE-- +> +--MITREQIYLDKKLETKSAVFEFITQEAEKLGVTVEQLVQDLWEREKVYSTGLQDQFAIPHTQS---EAVTRPAVLIIRLQDSIDWASHDGKPVQYIFSILVPKVSHLQIISSLATLLLEDSFKEAVAGAKSSDDVYHLLEQ-- +> +--IFSEDTVMLRLDVEDKDDVLRQMGKKIEATGCLKEHFMAAIRKREVEFSTAVGYDFAIPHGKS---DAVALPVVAFARLARPVLWDAEEDDRAQYVFMIAVPADEHIRILMKLAGAIMEDDFRDQIAAAKDEAQVIEIMTR-- +> +--MLNRNYIFTDISVSKSEKNLAKIAELLA-GPMNLDELLDGLLKREKEGTTGFTDGLAIPHATL---QSLADPKVGVVTFDTPIEWDSLDGKGVRTAFVLLTPDNIHLKMLSQLSRNLMKEDFVKQIQDNLNGDNLFKIVSS-- +> +--MITTDQIYLDQSLPNKEDVFQFISAEAERYHITSEQLEADLWEREQVYSTGLQDHFAIPHTQS---EAVTRPAVMVIRLNEPIDWESHDGKPVKYIFVILVPKVSHLRIISSLATLLLEDSFKEGIAAAAKPEDVYGLLHQ-- +> +--KFSANDVYLDVNEQSVDSFLKYASQVACNAGFAASELEQSFLAREQEYPTGLEDGFAIPHAKT---ETVKRPGFIYFRLTTPLDWQTYDDKPVTDVFALMVPPDEHLKMLASLSTALLEDDFKQQLRQLTSKEEIANFINQ-- +> +--LLSPELIFLEKEFDTKDDVMNFIGDVSVKFNITDEALVRDLWQREKEYSTGLAESVALPHTKS---DAVMEARICFIRLKNEVDWNSLDGKDVKYVFGILMPSNLHLKVIASLATNLLEDEFKEKLESLETAEEFYQYFTN-- +> +--KFSADDVFLDVNEASVEDFLQYAAKAAYDAGYTNEKLDQSFLAREQEFSTGLEDGFAIPHAKT---TAVKKPGFLYFRLSQPLNWKTYDKKPVTDVFALMVPPDKHLQMLANLSTALLEKDFKEKLRNLSSKEMIAQFINE-- +> +MAMFTINNMNMSLEGHTQAEILVSLAELATSLNLVVDSLVKDYQEREQESTTGFGNGIAIPHAKS---NNVKTAAILFGRSTTDIEWQSLDGKPVNTFISLLVPADVHLKLLAQLSRKLVHQDFVEILKR-GDTREVLEIINQ-- +> +ISLFQKDHVFTQVNGRSKNEILQYISEKAEDLQITNAGLLADLLTREDEVSTGLQQGFAIPHTKS---SAVQTASLLFLELEQPIEWGSFDDLPTSYLFTLLVPLVTHLKLLSGIATSLMEPAFIEKIQPGQTADYYYEVIEQ-- +> +TSIFQKNHIKLNIDIRHKEETLRYLAELALDVGVSHVQTYESMLKREGEFTTGFGEGFAIPHAKC---ASIVKPGVFLVKLKSPIDWNAIDGEPVSLIIGLLTPASIHLTLLASLSRKLMEEDFKKRFFLSHDQDELFNLITE-- +> +-MLIDRESIFLNKAFTSKDEVFDFIASHAVAQGWAVNDIKTDLWQREHEYSTGFESQIAMPHAKT---DNVIKAGVIFIRLNDAIEWQSLDGEPIKIIFALLVPKLLHLKIINALASQIVDDDFRRALFTLENRDALFQFMVQ-- +> +MTLFSQDHMLGTLQAANQAEVFQALANRAQELGVVASAIIADYTQREDEATTGFGGGIAIPHAKS---AQVLTATVLFAKLDPAVDWDAIDDKPVDTVISLLVPLAEHLKLLSALSRRLVYPEFVQVLKN-GSTDEVYELIAS-- +> +MPMIDKNLINLEVNVATQKEMFHYLADLAFQEDRAKAAIEQGLNEREAESTTGFGKHIAIPHTKN---SAVKEPTVIMVRNQEPLEWDSLDGQPVETIINLLVPDDTHLKMLAKLSRQMMHADFTDVLKT-GTKEEILTMLTK-- +> +MALITYADIDLNISGNTQYAVLKSLSQMAVARGFVNARYLQTLLLREKESSTSFGCGVAIPHGKS---AVVHQPFVLFARSAQGVDWQAEDGELASCWICLGVPQSEQIGMISKLCRKVIYPDFIAQIKS-LDSAGIVTLLNA-- +> +NEIFAEENIFFIEEGLDKNTFLKIVAEKAAEKELVSEACIKGLLEREQQQTTGFQEGFAIPHCKN---DTVYSPKLMYFKT-APIPWDSLDGNPITDSFVLLIPEDEHLKYLALLSRALIDDEFRSGIKASQTQNEIYRL----- +> +-MILENNQIFLDEKLSNKDNVMLFIAEKSKLLGITDKEIYNKLWEREKEYPTAVQDLIAVPHVKS---DLIKTAKLLFIRLTEAVDWDSPDGFKVKSVFVILVPEQKHLEILSKVAVSLLEEDFQSMILNMKTGDELIKY----- +> +MKLLSINNIHCNISANTKEDVFQIIAKIAVENGYAIDKVVKGLLEREAESTTGFLEGFAIPHTKN---ETIQHPGIIVQTMEKGVEWESLDSLPARFIIALLIPDTAHLKYLSTIAKMLMHKEVRDQLIQAEKEQQIYDI----- +> +--MLKQENVILDVNASSKEALFESISKVALETGVVAGAFVEGLKAREAVSSTGFMDGFAIPHCKS---ATVKDPAVFFIRLQEGIEWGLTDNTSAQYMFCLAISDGSQLKVLSKLSRKLVHADFRSQLKTADSSADIV-E----- +> +------EMVRLDPPLSTPEEVIEYCGNILVENKKAKAGYVKEMIDQRFGPYMVMAPGLALPHARPG--GNVKEPCISFVKLKEPVCFHHPCNDPVWVVFALGGVSDGHIELLQDLSSLLAGERMIEKLAALNTYEELEKLMEKE- +> +------PLAAVNVEAKDWQDAIRACGKLFIADGATEERFSDAMIRKEFGPYIVVAPGIALPHARPE--DGVIKASMAVVKLKTPVNFGNKDNDPVWLLVALAAIDQGHIQGLADLASVLGDSANVEKLKKCQTAAELLDVFYSA- +> +------NRIALQVEVNSPEEAIQFGGNLLKADGLINHSYIQAMLDRDQGPYFVIAPGIAFPHARPE--EGALKTGFSLVIFKRPIVFSHPSNDPVQLMLCLSATDQKHLTALMQLAQLLQSEATKEKWLQARDKEDILADLRHL- +> +------SRIALQVELDSPEAAIQFGGNLLEASDLITQAYTQAMLDHKQGPYFVIAPGIAFPHARPE--EGALATGFSLVTFKTPIVFSHPSNDPVHLMLCLSATDQKHLEALMRLAELLQSEALKQKWFQANDKETILADLNDL- +> +------NNTQIISKTDDWKSAVAFAVQPLIDSGAAESRYLQAIYDREIGPYYVLGEGIAMPHARPE--EGVNRTALSLVIVSEGVEFGSEGNDPVYVIFALAAVDHSHIEMIASLSHLFCDDEAAERLKRSKNKQEALEIIRQF- +> +------NLVAFNVKVDTPEEAIRKAGKLLADQNHVDCSYIEAMVRKDNGPYFVLAPQVALPHARPE--DGVKEASVSLVQLAEPIEFGNELNDPVKLVFALGASNDEHLEILKKLIGLLGNKETIQRIIDAKTYEEIEILIKGV- +> +------SYIQLDVEAENFEEAVKRSFDPLIEDGAVTDNYVESVLRRETGPYIVITKNIALPHAPVE--DGANKLGLGFVRLKAPVVSGHATNDPVKYLFPLSAKANEHIELLSKLADLLSQESFIEFLENVSSKEAFISYFNNQ- +> +------EQIELDVEVESPVDAIRAAGNLLVKTESASSDYVDAMVAEKLGPYIVLAPHIAIPHARPE--HGVKKQCMSIVRLKKPIKFGHPANDDVSLVIAIGGVDNFHIKMLQALSELLTDEDKLKRLKTSTDKAEILCTINKE- +> +------SSIALDLEAESAEDAIRLAGSLLCNTGAIEESYIDAMIDREKGPYFVLAPHIALPHARAQ--DGVKEPCVSLLRLNHPVPFGHTVNDPVQLVFALGGSTSEHIQMLRKLTTLLSSPGVVEDLQNAPDVDSVQQILRRN- +> +------QAINVDCAANCPEEAIREAGEALCRAGACSPQYVQAMVDRELGPYFVIAPGLALPHARPQ--QGARKAQISAIRLHEPLAFGHAENDPVQVVLGLSATSDAHIHLIQHIVTVLSDENNLHTLMHSRDPEQLYQLLASG- +> +------KLIRLNIDAKDWEDAVRQAADALLQNGKIKSSYIEAIIKKEGGPYFVLTKHVALPHARPE--AGVIESAIGIATLKEPVVFGNKENDPVKYLFCLSALDESHINALADLTGLLERKKFYEFLDQAKDASEVMQYIKSL- +> +------VRVSLDDGSLTPENAIRAAGQLLVDDGLAEPRYSEAMIGRDLGPYIVLVPGIAMPHARPE--AGAIRDGLAVLRLAQPVEFGHPENDPVRLVIPLVGSDHSHIDLLKRLSRVLMDPEAVNTLLTTDDTAAVTALFNGL- +> +------SAILPQADLTTSEAAIQVSGHLLVRNDYADKSYVTAMLESKNGNYIVIAPGIAIPHAAPG--SMVHHQGLSLVTLKHPLNFGHPLNDPVCLVFGFCAPDEGHLDMLMDLAALLEQPQYVTRIQNAATKEEILQIISE-- +> +------EHVAVGVQAKDWERAIEASGSLLVKSGAVTSEYVKQMVDKENGPYIVIGPGMAMAHARPS--EAVHTDAVSLAVLKEAVPFGNEENDPVDLVFSFSATGESHLHLIERLSRLLLDEEKVGQLREAKSAEDVYQIIS--- +> +------ELVNLHGSAKNADEAIEQAGELLVNAGYVSEQYVEKMVEHENGAYFVIAPQIAIPHARPT--DGVENSAVSLVVLKEGVNFGHAANDPVRLVFGLAATSEAHLKVIQKIVSLLSNSDNIEKMIHSEDYQAIGELVEG-- +> +------QAILIDNPASTAADAIQAAGQALCLSGACSQEYVEAMVAREFGPYFVIAPGLAMPHARPE--QGAIKAQLSLVRLREPVAFGHTENDPVQVLLGLSATSERHIQLIQHIVTLLSDENNLHTLMNSRDPEQLYQLIAGA- +> +------EHIITGIQVANWEEAIQASGDLLIKSGAVSTEYVKQMIQKDNGPYIVIGPGIAMAHARPS--EAVRENAISLAVLKEAVSFGHEENDPVDLVFSFSAKEDSHLKMMESLSRVLIDEQKVEQLRQAKTAKEIYQLL---- +> +------NAISTNQDYSTASTALHAAGTLLERGGFSNPAYTDAILDQHNGAYFVIAPGIALPHARPI---GVLKSGISILTLKTPLDFGNTANGPADLIVALAATGNDHLALLSQLVTTLSDRWRYQQLVAAESAAALYQLLE--- +> +TDNLKRQNIFLKAKSTNRWDLINEMVDLAAKNREVEDEIKKSLIDREKSMSTGIGNGVAIPHCTT---AKVQDIIIVISIIPRGLDFDSIDNQPVKIVILLLVPKTQHIKTLANIAKLMSNENLRNKLLAIKTPDGIIKTIKDF- +> +RDIVVEKAIIAPLKSTKRDDAIRELVEVLATQGAVKEELSKAVIKREKRGSTGFGHGVAAPHVKT---TEVQRVFVAVGIAPGGLEFQALDKQLVHVVFLLLSPEEEHIDAMECIFGVLTQDKFRRFLRQAKTPAEVWGLLEEA- +> +LTLLQPETVIFNLESGSKEEVISRLLQKAIDTHQIDEEILESLLAREKSMSTGIGSGVAIPHCSV---NLVDELKCVMGLNPNGIDFDSIDHQPVHIFILLIVPKQEHIKTLAQIAKALNVKEDREKLIRSGSFEEIQKAFSRN- +> +MDMVKNGGVLVGIEATEKEPAIDETLTAFCNRGKYSTKLKNAIMEREGTGSTGIGNGGAIPHCRI---GKQDEVQLYISVAKNDIEFQSIDGKPVKILFLIVLPKSLHSEALKAIASLMKNERFFRYLKEATSEEIILETIEDY- +> +GEILTKDQIIPSMKATTRWEAIEELIDLLVSCNKIRESIANVVKKRESSMSTGIGFGVGIPHAST---DLIYDVVGAFGRSQAGVNFDALDNKPVNLVMLFLVPQQKHLHTLANIAKILHNNDFRQSLEQASDADAMETLFKQQ- +> +KTYVHPECFIHDLAAKTREEALREIVSVAAAKGIIKAAVLERLLERERIQSTAVGSGIAIPHCFT---DEVADLVIVVARAPGGIAFDSFDGRPTHVVFLLMGNRGLHLKALARIARLIKSTAFIDRVVAADSVEGMVRAFEEE- +> +SSVLSPTSILLPIKSEERDSVIRELLEVMQFD--SEEKIYSAILEREAVSSTGIGEGVAIPHAKC---DIQEEMVIAFGITEKPVDFHAMDGKPVRIVFLLLSRKGPHIRMLANIARLMRNDRFAKKILLCKTRGEVLHLITEE- +> +LEILDPKNIIFDFKASTKEDAIRKMISHMVATQSLDEETVSSLMNREKSMSTGIGSGVAIPHCSV---HYVNELKCAMAIAPQGIDFDALDHGLVQIFIMLIVPKQDHIKTLALIAKTLNIPEEREKLIKAKNFEEIQKAFLSK- +> +LEILEPKNIIFDFEASSKEEAIRKMISHMVGTSSLDEDIITSLLNREKSMSTGIGSGVAIPHCSV---HYVNELKCSMAIAPKGIDFEALDHSLVQIFIMLIVPKQDHIKTLALIAKTLNIPEEREKLIKARNFEEIQKAFLSP- +> +SQYMSRER-ILDIETISKDDLLNKMADLISSDAK--IQMKRAIFEREKSMSTGIGNSIAIPHART---DSVTDFIVCFARIKDGVDYDALDQKPVNLVFMIVAPAKMYIKLLSRLVLRMKNDDFIQNLLDADTPERLFSLICDT- +> +KDIIPADRIFHYSSPADKYALLEDLMDRTLAG-TAFEKILEALLDRERSMSTGIGSGIAIPHCST---QHIEGMLASIAILNEKLPFEAVDDRPVGIVVLLLLSRDRHIKTLAAIARAFNQEKLRDAVAQTTTAEEVMALFEKM- +> +NKNL---------KAKDQIDVLYKIADIAKENKI--RTYLKGLLEREKQFSTGIGNGIAIPHCRC---DVVNEIEIIICALGEPIDWNSIDNEPVDLVIALAIPNNEYLSIISKLARLLMDENYVNELKSFKDEKDIIRKIKST- +> +-MIFQKRNVKLNVLTHSKNDALKQIAKFAYDLGYTSQKLFEAFIKRENEVSTGFERGFAIPHAKT---SVVQQPQILFCRFVNPVDWIAIDHQLTKHVFVLLIPEHEHLEILSQVAKGLMKAEFISKLTTTDNAELIYYLI-T-- +> +-NILNKDCVILDSQSQTKDQALLELAELGVKFKVVKQNLFEGFLKRESEFSTGLESGFAIPHAKI---SEIKKPMIFIVRYGSEIEWGTLDNSKVKVAIALMIPQSEHLALMSNISQRLLAAEVKKILKTSSDPQEIIEALSV-- +> +-ELFNGNLVSFNQEFTSKNDTLQWIAKQLVTYGCANKQVFDGLIHRENQVSTGIGGGFAIPHVQN---DAITNNVVAFVKVK-PLDWNALDNQPVQYIFTIALNKNEHLQLIAQLSRLLLEDKFKTGLNEISTYEQLIDLVKT-- +> +-LFFNWSQKTFKNKF----SFLKQAANALQKQAVINNVAFEALKKREEEITTGIITSLALPHLQS---QSVIEPFVAVFKVK-NLDWQSLDQKPVKLIFLIGVLVNLHLDFISNFSKLMLNETFASKVLNVTSYNGLIKLIDL-- +> +-QVINNKKIFLDVDVETKTDLFKFAANQLYDLNLVSEKFVKALLNREELSPTGMGDNWAIPHGQD---DSVKAASVLYIRTKKPIVYESLEGNSADKFFFIAVPSSDHVKILSKIATLLMEDEFKKSMSNIKNKEDIMTLISN-- +> +-EMINENLIKVGLKAKTKEEAIKELSQLLYANNKIKKDFEKDVLARERQMSTVFEDGIVMPHAKS---NSVNEASVAIGISKEGIDCNSVDGKKSRVFFVIAMPHDLHVKTLSEITSKLLDDSFKQTLFSAKNKGEVYNLFNE-- +> +-DILTRDNIILNLQGNNQKEVIDELIHKLTERRLTTERFKKAIYKRENEISTAVGYGVVIPHAQC---KSITKPTIIMGRSLQGVDYG---GQHTNLIFMIAAPENEHLSLLSKLSTFLMSETFRAKIIVATSEIDVIKAIQE-- +> +-NYLRPDCVALRQRADSLTGAVQQMVTLLNGTDNLTAVFAADVRARLALGGVCVGNGLAIPHAKS---TAVRQLQLAALTLDPPLPCDTPDGKPLDLLVMIAAPADLHVQVLAELATLFLDTDFCACLRESETPEAFCRAISA-- +> +-ALTNTGLIVLNSDLDNKDDIIRTLARKLFESGKLTDAFLQAVYEREALGETGMGGGLALPHGKS---TAVKEACFAVMTTRAVQDWESFEDDGVRHIFLLAIPASTHLALLAKLMQNMGDEEYSERLFSAQTPELFYQYLDT-- +> +-ETIERKNIIITKNIQNKEQLFHYLAEYMVSQKEIDEAFEQALWSREQLSVTGVGNDVAIPHVQK---EFITRPIVIFLKSETPIAYESIEGDSVRLIFMIAVPEAKHLNFLAELSRKLMDDDFRKHLLEASDVDALYHIISE-- +> +-DLLSEDLVFINADFSDKKDFVEKAAEALAKKKLCTDAFVKDVFAREEQGDDLPEEGVAIPHAKS---SAIKKPKIVAATLSKPWAHP-DSDNGISMVFLLAMPKDDHISVLSSLSTLLLDENEVKALRAAKSPKEFIKLMHV-- +> +-TLTHRDALCLNARFTSREEAIHALTQRLAALGKISEQFLEEVYRRESLGPTALGEGFGCAAWQNC--CGKRSGGLRVATLSEPLQWEGVDGPEVDLVVLLAIPPTTHMQLLTALTTRLADDEIRARIQSATTPDELLSALDD-- +> +-KYLINDGIVLEPKISNKWLILEQLTGFFCRQL-LADQILETVLNREMIVSTGLGGGIAIPHART---DLVQKTELLFARFKSGVEWNSIDGSSVNFLFLVIGPTEEYLFVLSKISKLLSRKQNKELL-HAKSSKEIYMILSSN- +> +-EILHRAVIKTDLEASTKDAAIAELVDSLIEAK-LLRKVLHALNARERSMSTGMEMGIALPHGTS---PDITNLVGALGISTAGIEWQCLDDQPANLIMLLVLPRQVHVRTLAGISHLLNEETFRTALINAPDADTILKLIRKE- +> +-HLLPPSSVLVPLRAETKQEAFDELFAGISMLR-LIHGLKEAVLRRELEGNTGIGHGVAMAHGKL---QSLTDIFLCLGISMHGIEYGSYDGEPVRLLFVAANPPGVYLHMLAVLSRYLHLAAFRRII-NSEGHIARVLLHGAL- +> +-EKLSSQNIVLNLKSDNKTDLIKELAERLKGHP-LFNQFVKDIFKREEDTSTGVGDGIAIPHART---NAVNDFVVAIGRRQPGIDFNAVDGQPVEVVIMMGTSLSLYLRLLAHLSHLLKRPGFNGLK-TAATPQEVIDLFFRY- +> +-EILDVRAILPDIESDKSKEILKILVNLVCQVK-IKDEIVKTLIEREKLKSTGIEDGLAIPHGKF---PKLQNMIAAFGRSEKGVDFNSMDGKPTHFLVLILAPESIHLKSLARISRMFKDKEFRNKLLVTSDPEQIYKIFLDQ- +> +-DYVPEN-NIFELKQTGKTEVLREITDRAKALS-LASEVFHQLLKREQLGSTGIVNGIAIPHCKT---DMIEPMSIFVGYSSEGIEFDAHDGNSVFLIFTVLTRKTIHLAALAAISRMISKYGLSNIS-DYLNPEALRRIIEEC- +> +-GILKPECIVTDIKGGSKPEILGQLAQPV-----GQFLLTEVLMNRERLGSTGIGEGVAIPHGKV---PGLGAITVALGLSAAGLDFAALDGKPCHIFCAVLVPSSGHLKALARVSTLFKSGELRHRLLAAADAGEVYRLCALT- +> +-DILKESRIVIDPTGGTKELALHVLAEVI-ATD-GVEEVEGPLLEREKLQSTGIGEGVAIPHCSL---QALHDQMAALLLSAHGIEFESIDNAPAQILFAVVSPKSDHLKILAKVSRLLRSPETRRLL-EATTSEQAYSLILEH- +> +-DVLSPTKIQLRIPVTSKRELLDRLLAIVDAEG-LSERARQAVFEREERLSTGIGYGIAIPHAKT---DAVARATAALVTCAQPVEYDSLDGKPVDIAILILGRSRTHLQLLGKISRLVSSEQSRTLL-QARTPNAVYEYFQQL- +> +-DLITDDLILADMKARDKRTAINEIVAFMCARN-IARKVEAAVLRREGRGTTGIGKGVAIPHAKN---CGQVDIVAAFGVARGGVPFAALDGEPVRLVFLVVSPRNDHLRVMRKIAHLARDDKT-RFL-ATTRDFSTLRALDEV- +> +-ELMSTNRVAYRLTASDKEGVLKELVQRCFIQL-EQSGILEVLKERESLGSTGIGDGVAIPHGKF---PRLGHLAAGIGIHEGGVDFGALDGNESQFFVVLLAPEGQHLKALARIARLFRDAGFKRRLIDAQTTQELFDLIAQE- +> +-EIIQKSLVCLNATESEGQEVITALIDKAAGLL-ARDTAVRAVLNREMSASTALPDGIALPHGRI---ECVRDIICMLGVHPAGIAFGAPDNQPTHVFVLLLVPACNHIHFLAKLSRRLMEASVRELL-AARTRDDVMRTILSN- +> +-KLVARAGLIQELEASTKEAALQELLGAAQDVG-FRKTLQKRLSDREAIGSTGLGNSVAVPHVKG---DGVDEITLVVARCHPGIEWQAIDGRQVHVLFMLVSPMESHLKCLRWIAGLARNTDFRRFLLDADGDDAIRDLLVEM- +> +-EYFSKKAIVSQLKASDKKGAIKELVQVVKDVY-PVNDIADDVIKREKLGSTGLGKGVAVPHAKV---VELKKVIGAFGRSTDGIDFDAVDGEPVHLIFLILSPIDLHLEALRKIMQAIKRPNFCKFLNSAKGIKDIEDIFVEY- +> +-AYLSHDRIYLDMPLPDKASVLKFIAESFVRHK-AVDAVHDVLEKREKLMSTGIGGGIAIPHALS---SVIGEMVIVLIRLKPGIPFEALDRRPVDVVFGLAIPATCHLKALAGISALCKNPGMLTIR-SVVSPRMLWQQIEAV- +> +-KVLSLDRIVVGVKNRDKIGILQELLEVAATSG-IKEELLKSLLQREQIQTTGVGFGLAIAHAKS---DDVEGVVLSVGLSEEGVDYDALDGKPAHIIFMLVSSPTEYLSVLAKIARIFREEDFREAVMHAGSPEKVMNLLKER- +> +-EALNVSRITLDLQSGDKQAAIRELAQLAGDHG-LVAGYVESVIEREFLLSTGVGRGVAIPHAQS---GAATGLSCCLGVSRAGIDFESIDDEPVHIVCMIVAEEAAYLLLLSRISRLFAQRHVRQQVLRAASPEDLLAAIRAA- +> +-EFIAASAILPDLKAETARGAIDEMVGQLVTIK-VRRKVVDAILRREKKGTTGFGNGVAIPHAKH---EGVKGVVGLVARSASGIDFAALDRQPVHLIFLLLSNPEQHLKAMEHIFRSIKNDNLRRFMCQASTRDELVDVLREA- +> +-DILNESRTFFDVPGKNKQELIVNIVERAKASN-IVKKFTQEVLEREALGSTGIGDEVAIPHART---ENVNQLLMAFARAKEPIDFEAEDGLPVRLIFLMGVPIKSYLNILAKLSRVIKIQKVRVLS-QTNNPKEVIEIIKLA- +> +-ELLNETTMKIDLEARNKSGAIEELVDLLVEEH-IRSHVIQAILQREEMVSTGMEYGVALPHGAV---SCVEEVVAALGVSKQGLDFQSIDGRLTYIIILLVLPKSAGVRTMAGISRVLTSDGLRDRLRAAGDAGEIMDIIIEE- +> +-EYLDQRNVLLDIESPDRDALLRRLVECLVSTG-LVEEPLRRLIEREEVMSTGIHPGIAVPHAYT---GAAPKSVCALARLASGMDFRSLDGGKVFIVFCLLGPPEQHVRLLARIARLIEMPGVIDLR-MAATPDSLITLLRTA- +> +-EVLLEENVNLDLKAGTKEEVFTQMTRMLYENG-IEQPFIDELVHREAEGVTGIGEGIAIPHGRS---AVVNRSVIAIGRTRTDVSWETFDDKPVRCIIMFAIRD-QHIMLLSHVAQLLLDKDVITLH-HARTVEEIVNILRKE- +> +-DYTKVSLLKPRTGAVSKKKVIEELVQILAENK-IVSPVCKAVLKREALGSTGIGQGVALPHVKI---KGVKNISFVFTNSETGVEFNSLDGGPVNIIFLLIGPEEEYIKALSLLARNLNDPYFRRALAAAKNGKEVMCILKKT- +> +-DILEPNAVITPLKGTSRDEILQELSTCL-ANH-EAEHIYDVLLSREKLNSTGIGDGIAVPHGRV---NGLDKVKGALGLSPEGIPFGDSEEERTHIFFVLLAPHGAHLKALARVCRLLKGTDLAKRLITLETSSAIYQTLSEK- +> +-DVLERKTVIPNLQSRSKPDVIRELAENLASAY-NDEKLIEVLMEREKLCSTAVDSGVAIPHAKM---SGVSDIIAGFGRSIEGVDYDSLDSKLTHLFIILVAPEGAHIQLLARISKIFKNPELRARLMTLETQDEIYDSIIME- +> +-EYLRLDQVIFNLKATDKIQALEELLDVLVKLN-IKKPVLTRIIDRERLVTTAIGHGIALPHARL---DTGGDIAVVVGRSVAGLDFEAVDDKKVHVIILIVWNPGLFNHLFAGLAQFLIKPGFRRIF-NARSKKELH------- +> +-AFTGTKLVDLSLSARSKDDVLASMVGL-ARSP-VGARFLTDVLAREKLVTTGVGYGVAFPHAKS---AAVKKVVFAFARTAEDVPFEALDCNPVRLIFLIGAPRGVYLNLMARLSFLMKDEGNRALL-SAGTTKAVFDIFDSV- +> +-QYLPPEQIFFFDHG-DRMEVIEKLCKGL---L-EIPAARSKILEREGEASTAIGKKVALPHASI---DALDDFILGVAVSPPITGWETFDMEPLHIVVMILAPSESYLEILSEISKKLGQRRVVEIL-KARTREEVAKIFHS-- +> +-NLLSTETIVLSLKHSDKEGIIEELLDLAVKTG-VRKKALKALLDREDLGSTGLESGLAIPHART---NAVNGVALALGISKTGIDFQSADGKPSHLFFLLLAAESVNVQVLALIARMNLSSEFRSKMVSVDSAESALEIVRAM- +> +-SLLEVRTIELDFAKRRRQHIVERLVEL-AGVH-LQGRLVREILQRDSEVSTAIGDGVAIPHKLT---PLVSQPQVAFLQTRKGGHFSSPDGIPVRLFFLLLAPENEHLRTLSKLARLLHDARFRELL-EATVPQAVVEMIRSR- +> +-QLLNPSLVALNVRAAEKNGAISFLCDLISQ-N-KPEPLYTTIMNRESLQSTAVGHGVAIPHARC---DVT-DFIVAAAVSEKGMDFSSIDKQPVNLVFLIISPKSRYLQMLSQIAALLSSEKNRELI-SAKTPEEFIEIVKRN- +> +-P---LDFTTVSLTGSTMEAVVRELFDPLRNSS-VSKQAWVDLVARQAAGSVALDETVAVPHART---GAVKRLVIAGGRHVNGVPFDE-KHQSVRLVFLILTPKAEYLRVLAALASRLRDPATRRLL-TAGTSDEFARLLEDR- +> +-EFIEASQIRIIPAGATKHEALEILVEALCQNP-IKEVFTRAVHEREAIQTTGLGNGVAVPHVRI---DEVSAPTVALGIAPDGLDFQALDNRPVYIIVLFATPQKTYLSLLAKVMVTLREEETFALA-ACRTVEEVTSLLGIS- +> +-EYLDPRLVLPDLHATAKPAVLQELITPVADVL-GVKKALQVLLEREYLGTTGIGDGIAIPHGKL---AELDKIVLVVGRSKDGVDFEALDLKRCTIFFLVLAPEGMHLRILAHISRLLKDEAFRRDFLSTPDKESLWKLLART- +> +-TYLKPEAIMLRPAAADKWQLIEALCRQLANSC-VTNQAVKTVLQREKSASTGMEGGVAVPHSAV---DGLPGLMVGMAVMPDGLEFDAIDGSVTTVIVMILVPKLGHLRLLAEVARRVSDLGFQHMF-AASSTGQIVDLWL--- +> +-TILSTKTVKIGLKSLDKQGIIDELIAILHDAG-IVQAAKTAVMERENRLSTGMKFGIAIPHGKT---QTVDRLVACVGISRMPVPFDSLDGEPARIFIMTLSPPGPHLQFLAEVSQLFKDETRRERVVEAGSPAELLELITG-- +> +-DYLKEENIKIDLGARNKKEVIK----GLLK-S-SSKKILQGIMKREELESTGFGNGIAVPHARI---DGIPSILILVGVSREGVEFDSLDGKPVNLVFLILAPKKLYIYILAKLIKILEKKKNIELI-STDTPQSFIEKLRSI- +> +-NILSEKLVRYPLKANSKREVISELLGILVAEG-VPAQALSDILEREKKMTTGIQNGVAIPHAKT---RAVEKLTACIGIKPEGLDFQSLDGKPSQIFILTLSPYSVHVQFMAEISMVIKSEAIRNTMIKATSKGEILSVFGL-- +> +---MNEEDIIINLKARNKKNAISVMLNCLVNTK-IKRLILKVIMQREDMGSTAIGGNIALPHARL---DCVKDIVSCIAISREGIDFDSLDEEPVHIIVLLLSNQGLHLKTLAYLAKMLRDKSFVRKLEAAKEKSEVISLIARQ- +> +-LHIAPEQILLDLKAGTREEVLYELAAAAQSRC-ARELVAEQLLERELQESTGHGNGVAIPHTTL---DQLGETVLLFGRNLRGVNFYAADKRPVQLFVAILVPQATYLRTLARVSRLLQQPALRRLM-QAATVEEVQEVFALA- +> +----MDEKKVIFLSSLKKIDALEEMVKALRERG-L-EGVFEDLKKREELGSTGIGRSIALPHSQG---EGIEKPLIALGVSRKGVDYDSGDGLPVHLLFLVLSPMGRHLELLAAAARLAKTLSGRPYL-ESGDPERFFEVLRQE- +> +-MLIKSENIFLDVKGKTKYDIIRNMINSSTIEE--KEYAYEKVKEREELQPTSVGNGIGIAHAKI---EKIKELDILVGVLKKGVDYDAYDDKPVNIIFVILSPVREYLSVLSKISRFCRKENMINII-QENNREYIIDLFSQL- +> +-NYI-KGKFKSSIKAKEKRQAIKELFETTDQ----PPPVLNKVYARERLFPTGIGHGVAIPRYIG---EEVREITLVLGLSRVDMEFGALDHKPVKIIWLLLSPDEKYTEILIRLIRLANTEEFRQVP-NLTSYEDLIELIKEI- +> +--------MILHLQAQKRMEAIRELASRLEGSD-IVKRFLSLVMQREKIETTAVGHGVAIPHAHG---DCVKSLVIGVGVSRQGIDFGAMDGEQVGIVVMIASPVQDYLKAVSRVARLLNQEDCRRIL-NAQGVAEVIEVFKQI- +> +-AFLKENNIFFDLEPGEKRHVLEEFVSALKKRG-IEKVILEELLKRESLGSTGLEKGIAIPHALI---ENIDDPIVALALIKSGVNFDAVDQMPTYIILLLLGGKGFQLRLIAHICRMVKETDFVEKAKKAESSHD--------- +> +-DFLKDDLFIINET-FDKKEALTFFSNVLKEKGYALKIVLEKAMARENEFSTGIGNKIAIPHIRD---NVMKTPVILFAKVK-PMDWQSLDGQKVEVIFFIALDQNSHLEVIANLSRRFMDESFIDNLLKINTFKELITLLSN-- +> +-DLLSPAACDLEAH-VTKRAALEHLLRLMEHTGCIAKAFRENVLERESSVSTGC-EGLAIPHGRC---AAVLHPALAVMRVKEGCPFDALDQKPVYLFFLIAAPDSAHMQLLSRLAQLLMDKSLVQSLLAAPDYAAFCHTLDL-- +> +-PLITPELVSLDANLGTKTEVITSVAGLIAAAGR-ADGLAHDTLDRESKSPTGMPGGFAIPHCRS---AAVSQVSLGFARLSPAVDFNGPDG-PADLIFMIAASEADHMKLLTKLARALVNPEFVEQLRQAPDAQTVVDLIGG-- +> +-ELFTAQSIALDEALQTQEEILSRLVELQATHGNITEAYKKALYAREAEGSTYVDNGITVPHAKT---NVVTRPSLAALRLSTPVQYNAEDDGTTDLLFAIAAPESLHVDMLARMMQMLMNEDFVEKLKAAKTPKEFLECIDA-- +> +-SLFSLNAIALDVAASNQDEIIDKVVELQSTHNNILEAYKKALYAREEEGSTYVDNGITVPHAKS---DVVTRPSLAALRLSSPVQYNPDDDGKTDLLFAIAAPQSLHVDMLARMMQMLMNEEFVEQLRTAKTPQAFLDAIDK-- +> +-ELLCLERIDLNAN-VNKNDVINYLIELMMVNDNIINVYKQEILNSKIQNINEIIGGITIVYAKT---EVVNKPGISVIVVKNKIDYDSLDELSTRLIFMIVMPEDLYLDIIQQLSQMLMDHNFKEQLINANSPNEFLSLISM-- +> +-EFLTAENIHLDTPASCKKRALEIAGKLLADLSDCPIACFDALLKREKLGCTALNNGVAMPHAKL---ANACKPIAVFLKLEQPVDYEAQDRKEVDLIYAILFPEHHYKAYLPKIAEKLSDKNIIKQIRTAETEEDIWQLFCY-- +> +-DILSPHRVLVDCHISSKKRALELLSKMIAEDGVTHQDILHGFLARERLGSTVITKGIAVPHTRL---AQVERPIGAFIKLHEPIAFDNHDEHNVSMLFGLVMPEQEHISVLSCLAECFQCQTRIAQLNDTHGIEEAYRLLTL-- +> +-SLSPNPLITIDLDVHSKKRTIEHVASLISTR--CINDILESLILRERLGSTAIGSGIAIPHGRL---AHLDKAIATLVLLKEPVDFDAADKMPVRIVFGLIIPEEQHLTLLRSIASIAQDPTALHILNSNKDAHVIFHWLKN-- +> +-ELVKADSVKHDVDAGSRKRLFQIIAEASVDPDKAVDEIYDALVERERLGSTALGDGVAIPHCRV---G-CERISGAFYTLAEPIEYEAPDEKPVDLVFVLLVPKKAHIDALQRLAQLFSDASHLACLRNAQCNESLFAELKR-- +> +-EYLSLDRICPCIHSSSKEELLLQISQHLALA-HTAQDIYATLMAREALGSTGIEDGIAIPHGRL---TALQTPLLAFTSTTAPIDFGAIDELPSDLFFVLLAPLSTHLAILASLSQLFHQPEFSQQLRYCKTAEAVMHCIQR-- +> +-ELINPDNVLCNAHARSKKHCLQILSELLARS-ISNEEIFSRLIERERLGCTSLDAGIAFPHCRV---EGVTASSGALMKLSSPVDFDASDGEDVDIVFGLMVPVDNHRADINMIASSLMSQDLRAAIRAAKTSKELYQALLS-- +> +-TLLTPERIAHAQEMSSRKRVFERLAELLASAL-SAEVIFDALTNREKLGSTALGNGVALPHTSI---V-IPEARGALLLLEEGLKMDAPDKKPVQVFMAILVPASDFSPCITELASILLQKPLLKQLYHYREPADILNYFNG-- +> +-KDIEIDHIVSDANAPSKKSALSHLADHI-AEV-VAPVVLDHLIVQEAHQNSSMGEGVAIPTLTL---KQAREPYTVLMRLAKPIPFDSVDGKPVDLICLVISPSPLKLRRLSRIARLFKNKELLEKIRNTEDEDTIRALIHS-- +> +-DLFPLQRILIDEVYQSRKRVLEVLAGLLADDGAHATHIFEILIERERLGCTAIGHGIAIPHGRD---KDILRPRGAVIRLTEGIDFGSADNQPVNLIIGLIVPDESHVAILGILAQHLADDKDREAMLNTQSAERIRGLMRE-- +> +---------MPLVLHKPTQRVLEVLAGLLADDGQESTRIYEILIERERLGCTAIGKGIAIPHGRD---ASTLRPRGAVIRLTEGIDFGAIDNQPVRLIIGLIVPAENHLAILGVLAEHLSNEGDLEAMMQTQSPERIRGLLIE-- +> +-AMLEKNCTKSAVLFNSKKRILEYIAELAHQQEMSEYSILEALMTREKLGSTGIGGGIAIPHGKL---DCVTSPILIFVVSQDPIPFDAIDNQGVDIFCAILIPKQAHLTTLSGIAKLLTQKDLTKKIRHASSDQELYQLLMD-- +> +-SIIEPSRVLRNVDARSKKHALDILSEMIAGA-LAQGAVFDSLISREKVGCTALPGGVAIPHGCI---DGLERIIGAFVKLAHPVDYDTPDGVPVDLMFAIVLPDTERKACLKEAGQIFGDPAFQRMLRSAKSSRTLYDMIIG-- +> +-LLLSPERTLFVQALESRKRVFDTLASLLAHKL-DKVTIFDALIEREKLGTTTIGKGVALPRARF---P-ITHPCAALLVLKEGITIEAPDKQPVSVFLALLLPEQPYSDLLSDLTMRIASRSVSEELSEISEPQIAVNYFET-- +> +-SVLELTTVHRFSDLVSKKKLFEKLAELL-IVL-TFLRVLGNLNAREKLGSTYIGKGVAIPHCKI---AV-EAVKAVILILDEKIKYSESNQQQADIIFALLVPEDQHLHLLSSIARLCEDNNWLDGLRKLNSEKEITNYINK-- +> +-DLLSPDFIVMHPKVSSKKELFEQLLEALKPQ-SQFDAASEAVWARENVMSTAVGFGFALPHGKT---HEVSQHMGVFGVLAEPLDYDGDNKEQVQLVFLLVGPKANHIKLLSQVSKLMNKEVLRQEILRASTAQEVYGLLKE-- +> +-DLLNPSCTSAQSDVSSTKTILDKLAHLLGEQ--GSDKILEELVARERLGSTAIGHGVAMPHAKL---SSITSPMLAIVTTQNGIDFDAPDDELVDIFFGLILPDGEHLQSLKCITELARQEEVRKSLRAAADQQSLVDVAIT-- +> +-HILVRSRVLSSCHVNSTKASFEIGAELIAST-LXARELXDAXLSRXRLGSTALGNGIAIPHCRS---EXCTHPSAALMHLHESVDFD---GELVNLLFIWVVPQTVHLNXLDALSRIFGDIENVKKLRXTKSNEELFDIFIK-- +> +-ELITPGRVACNIKVGSKRRALELLGGLIASDDLTQPEVFESLVERERLGSTGMGRGVALPHGRL---KDRPRAVGAFMKIEGGVDFDATDSAPVDLIFGLLVPENEHLQILARLATMFSDTELCASLRNCANRTQLVRHILD-- +> +-NLLPINNIKIDVDLSSKRRVFDEAGLIFEES--SRQHIFEAFLEREKMGSTALGNGIAIPHGRI---DSLKKSTGAFIRSSNGIPFEAPDNNPVFLFFFLMVPSEMHLQILSELSQLFGTQTVVKKIKESRDPKVIHQIFSD-- +> +-EILSPERACSNLQASSKKKAIELVSEKISLS-LKSGHMYRGLIDREKLGTTAIGEGVAIPHCRL---DNCQQITGGLFVFNTSIDFSAPDEKGVNIIFALVVPKSQHLKTLSALANFFSKPSNRYELLNAGNDQKLYHAALK-- +> +-TELGLHHALCGEXLLSKKRIFERAAEVMGIADLQSXPIYRALLAREKLGSTAIGEGVAIPHCRI---NHLSEAAGCLVSLKEPIDYGSTDGSEVDIIFVLLVPEQDHLNLLAGLARVFSESETRAKVRSANSAGQLTDLFIT-- +> +-PLLSPTRIALQVSLSSKKKSLQAVSELFAKDSISKDLVFDALTDREKLGTTGLGDGIAIPHCRY---ADCCEPLCAIMTTDGGVSFDASDGKNVDLLWALIVPIDDHLQALALMAEKLTKTEICQAIRQAQDPAKLYLLLTN-- +> +-ELLSPARTQRGVKGTSKKAIFEEVAALVAADELDVGDLIGKLLAREKLGSTGLGGGVAIPHCRL---ANCAEPLGALVTLGEPADFDAPDDTPVDLLVVLVVPEQDHLDILASIARLFSQAPLRAALRACESNRALYDTVVG-- +> +-NALPIDNILLEMSATSKKRAFENISLFF-ERI-SSSAVFKSLLAREKIGSTYIGNNLAIPHGYV---YDLKKTIAAFVRLNRPIIFYNQNRQLVNTLMFFLVPLEEHIKILTKLTSNLLDKTTNKILQTEDKKIIYNTIIKQ-- +> +-DLLGPDAVAAGLRTGSKHRLFEEIARRIAPG-DVALGVLEALTEREAMGGTALGAGAALPHGRC---DALASPVGGLFRLATPIAWGADDGRPVDLVAALVVPVGRHLELLAELAEAFADPGLCARLRVAPDAGALRGELAQ-- +> +-DIFTPELTICAQNIDSKKQVLSLISGLIAEA--KAQHILESLTERERLGCTAVGYGFAIPHARI---QSLTKALCVVVTLPAPINFDSEDHQMVDSIFGLLVPEEEHLEHLSEIAQRIKSSSFRHHVKNADNHSALYQALVQ-- +> +-NLLTPARILCDVRGASKKKILEHIALRISEE--NPRELLCRFVHRERLGTTVLDSGIALPHCRS---KCCPAPVGLFIKLNTPIDFNTTTHTLVDLVFALVVPEQNHINLLKQLVTRLQSQKLLHDIRVTSSPEEIYRRLIA-- +> +-DILHPSHIAILSDCQDGDALLNRLAGLLAGDPQLCEGIIASLRQREQLGSTGIGHGVALPHGRN---AAFDMARAAFVRLPRPIDYAAADGVPVDLVLALAVPAHQHLQLLADIAERFSNPALRQALRLAPDAATMHTLLTQ-- +> +-QLLAPDRVCTGLSGTSKAEVIDALVDVLADHAAIAEAVRSAIFEREEKMSTGVGKGLGLPHAKT---PAATDTVAAFATTNEPVDFGAVDDVPVRLLLLLVGPESQHIKILGRISRLVSRDSMRERLVAADTPETVIEALREG- +> +-SILKPGLIKVPLDGESKRAAIDELCDLVCTSSAVTDNFRKTVWEREGQRSTGIGEGLAIPHGKC---PGVREITMSIGIPQAPLDFDAIDGEPVRMIVLLASPAADHIQALGRISKFMSDPTVRSRAYSADCGEDLYQLLAGL- +> +-ELFAPERVCLKLNAATSEEVLAELASLLGGRDP-GEIIRDGMAAREVVCSTTIGGGVAFPHARV---EGVTAVRAAFVRTAEPVPFGAADGLPVDLFVGVVGRFAQLISTLSRLLWIFRTEASREWFRQETDPARIVQGFSRV- +> +-DTLKSGCFCLELAATTKDAVLEELVAILYNAGKIQDRVLAAVREREQKMSTGLSDGIAIPHAKT---DTVTEMTTVLALKHNGLDFQSFDGQPSRIFIMTISPAGPHVRYLGQIGKLLKQPAIRERLMASVTPDDIVRALTDL- +> +-TLLPKESIASIPGVNSKEELLHALVDLLSNELTPDTRIRESVLLRESVMSTGVGKGIAIPHGKC---SSVDRNFASFIRLDQPVEYQSIDNVPVRYAFLLVGPMGEHIKLLSRISRLLNSRSFREKLDATTATDELCAMIQKE- +> +-DLLAPDRVAVRVSVATREEAVDIAVGLLADCPSVVARLAADVEGREALMSTGVGEGLALPHART---SAVTSTVATLCTLAVPVDWDAHDGAPVDLVLLFAGPEATHVRLLAHLSRVLSAAKVRHRIAEAETPEALVAAVVEA- +> +-EFLAPESVSMGIAAHDKAELMAAMLKLVAGRPQITSVVERDVQAREQAMSTGVGKGLALPHAKT---QGVSETVAALAVLAKPVPFDAVDGLPVQIVFLVLGIPSQHVKILSRVSRLMNQEAVRRRMLAAKNDDELFAALEDA- +> +-DLIQEKTIRAPLEATDKQGAISELVDLLSDEGCITEIIKQAVWERELQRTTGIGEGLAIPHGRC---DELDSMVMAMGRPSTPIDFASPDKRPVELIILLVSPTSDHIQALGRISRLMVDRSFRESAYATENANDLFALFQNA- +> +-ELLSPKNIGLPLRATSRDEVITELIELVAASGDISDEVLRKAKEREEILSTTVGKGLFVPRARS---RHISRFCLSFGIAGSPLDLGALDGNPIKLCVFLGVPDEEGVEYLVRIFRLFNQDSFRSALLKAKSRKDIIHVFEEE- +> +-ELLHDGNVIADLDVTTKQEAITTLVHTIRESVGEEQTALTAVLEREAVMSTGVGKGLAIPHGRV---KGIQDNFVAFGKLRTPIDYGSIDQKPVSMIFLLIGPESQHIKLLSRISKLMNNDAFRDRIASCTSSAEIIAFFTEE- +> +REFFSEDAIKLDLQATNKDAVLKELVGLLKLDDKADAMLFKMLKRRETLGSTGIGQGIAIPHCRS---LVVNRLRVAFGRRLEGVDFKAIDDRPVHYFFLIVAPPNQYLPVLGKIAQFAKESDVPTRLAKLKLSTEFLELLEEK- +> +YLLLHEENIVVGLDALNHEDALKKIVDVLPGWSLQGQKILELLILRERIGTTAIGHGIALPHCFS---SEVHEPIVAFGVSSSGVPFPSLDGRPVHFIFVLILPREQKRQILQNIKWSLCDRYLQERLKGAQTASEIHRLIVSE- +> +SGFLKKENVILNIKSKTKDGALEEIVNKIDLT--KEELVLLSLKQREVLGTTGIGSSIAIPHARS---VVLNKLCLYVGLSRTGIEYDSMDGKPVYILFLIIAPPNQYLILLGKIASLSKKLVRKKGYLKVENEDQLIALIKKY- +> +LALFEKELYIPELDAGNKQEVLEEFVELLHREERVFDIVLDMLLKRENLGSTALGNGLAIPHGRT---LTTRKLVVAFGKCTQGLDFDAPDGKPVHLFFLIIAPYDQYLPTLGKIAEFFRKKRLREKVLQVSNFEEFVDVLSSE- +> +SHFLKKENVIFDLKSKTKDKALEEMVDKIKLS--KEELVLLSLKQREVLGTTGIGNGIAIPHARS---VVLDKLCLYIGISPKGIEYEALDGKNVNIIFLIIAPPNQYLILLGKIAALSKKLIKKKDYLKIDKYEDFIALIKKM- +> +MDFISRENVAPDIKARNKEELLTELVGMLHTCGKIGAPLVKSLLEREKIMTTGIGRGIAVPHAVS---PEVKDQSIILGRIPEGAEYESLDRAPVYFVFLLVGPPSIHLKTLARISRLIQHTNFVESIKKAVTAEDILKILAEE- +> +LKHTSPQLFLPNIQATDKNSALTELVKGLIDGTEINDNIMQMLQSRENLGSTAVGPGIAFPHGRT---LSVQRLTILIGRCPEGVDFVSEDGNPTHLFFVLIAPPHQYIKSLATLIDCVQDADLRNKLMAAEDYDAFCAAMKGD- +> +TESLPIVSIDLNLKGKDKVQVLESLVALAGKAQTFEGEVVAALLERESLSTTGIGNGLAVPHCKT---PQAKQLVIALGRVPQGINFFALDGHPVRLFFLLLAPQNSHLKALAKVARFAKNPSILQELMDQPDPERLLAFLKEQ- +> +LSYFHEDLFIPELRTSSKNSVLKEMAAWLESSKKVYSIIYDLLKKREELGSTVIGGGVAIPHCRS---IAVEKLTVLFAIKSKGIDFKSNDRKPVKLFFMVVAPP-NYLVFLGKLVELLTDRKIKKMLSKVKSFEEFKDLISGI- +> +SRYFSEHLFIAQLKAKNKEQAISELLDLFVKEKYIREIVLEMLHQREKLGSTGIGKGVAIPHGRT---TAASNVLIAFGKSEAGINFDAIDGKPVHLFFMVIAPPNTYLPILGALVTMLNEKSNRDKLAKVKDFTEFLPIITGE- +> +TDFLDERFFLQELNSRTKNDVLQELMRPLIESEQVQELLHETLRQRELMGSTGLGKGIAVPHCRS---TLVSRLLLLVGRSSKGIDYDAVDKKPVHLFFLIVAPPNDYLPLLGKIVEIVRDGRKRKAMLKAE---GFKALVRVF- +> +ITYFDEQLFLPDLKATSKDELFEEIVDQFVKIKYLKEILLDMLRRREQLGSTGIGKNVAIPHGRT---TSASDVMIAFGKSKQGIEYNSVDNKPVNLVFMIIAPPNIYLPILGKMVEILNKSKTRSKLMEAETYEEFIDIILKG- +> +LIYFDEQLFLPDLLAKTKDDLFEEIVDQFVKVKYLKEIVLEMLRQREKLGSTGVGKNVAIPHGRT---TSASDIMIAFAKSKNGIEYDAIDGKPVNLIFMIIAPPNMYLPLLGKMVEVLNKSKNRNKLMQAETFDEFMEILSKG- +> +VDVLDKNLIKIPLAGNDANTVIEEMVGLLSDALNLGDDILQAIKRREALGSTGLGKGVAVPHAKT---SAVQSVKLVIGVTSHPVDFNAPDNEPVSLFFLVVAPPSSHVEVLASIARTCSSAVMMKHIKNAHSADAMYSLFRE-- +> +MLTLHQECILLNLQATNKEGVLEELTQLAVQHYNNLQQLLATLLEREQIGSTGVGNGVAIPHGKM---LGLEEIIFCFGRSTGGVNFEAIDNRPVFLFAMLLSPLSDYLKALAHVSTVLKEQQNRIMLLQDPSPKDVVSLFTPP- +> +REFFSEDAVALELQGTSKDEILKELIGLLKLDEKSEGMLFKMLKRRENLGSTGIGRGIAIPHCRS---LVVNRLRVAFGRKKDGVDFKAIDDKPVNFFFLIVAPPNQYLPVLGKIAQFSKEGDVPTRLLELTSPAQFMALLEEK- +> +MDLLPRRAILTDFEPPDKIAALKKLSELLAPHTSSLDEIFRILLERENLGSTGVGRGIAIPHGRC---KNIRRPVLCFAKSTKGVDFGASDGKPVHLFFAMVAPETANIKVLAKMAEILKNPTARDALFEAHNADEIAEVLSRY- +> +--LRKYVEVSFSNFNTDKMKLIEEIAEVIIWLDNESQTIAKGIKEREALSTTGFGNGFAIPHGKI---EGLESPILAVFKLEKEVEWDSLDDEAITQLFIILVPVDTHLALLSTLSYHLMDEEVQRKINEITENEEMKRFIEM-- +> +--VKSEVIIRFDNQATSKSAFFQEAAVALGL--LHIPTIVLALEERERLSTTGFGDRMAIPHGKV---AGLDIPHVIFMRLEQPVEWEALDDQPVNECFFLMIPANVHLKLLSKLAYHLADEVYQQKIHETRDAEEMMQVIEE-- +> +--PVIHAAVEVKSDADGKDRLLKEIVQLVTACSFSFNEVYQEVMTREELSTTGFGNGFAIPHGKS---SDLEKPIVSVCKLARKMEWEALDDEKVDTVILLIIPKDLHLKLLSALSYNLMDQNMQEKIREADKEDELSDVIES-- +> +--VDYYIDPSKTFQSGKKTEIFKEILDDVSHSAFDFEEVLQEIKKREALSTTGFGNGFAIPHGKS---SQIHTPIVVLMKTDQKLEWEALDGQPVSIIFLLIVPKAIHLKLLSRLSYHLMDKKIQEAFKNAETKEDCEALLNQ-- +> +--LITPSNIIIDGDVKDKEAGLYM-IAEKEELGISAEETFKGFIEREQEMSTGFTDGFAIPHTRS---DSIQYPSVIVVRLKHELNWETMDGQQVKIVIALLVPKNMHITLLSQLSRKLMKASFREEVMNSFDTESLFGCFKE-- +> +-NLLSIERVIPNLYAADKSDALRKLAA-VANSATPADLVVSAVLDGAEMPAFGPGTGISLPHAFI---PGLGDPFVIFAKLNPPVDFGSTDGSKTDLVALLLSPLRGHLQALACVARTLRDVHVRKLLRGAESRDSIYAVLCGY- +> +-EILNTNQIHFDFIATSIEDIFQHVEAGLKDNKIRFRRIKKVLRLGHEDTSYTIGNGIAVLNAKT---FGVNRKVIGFLRLSKPIDFKADDGKQCDLIAVILSPQPLHLRRLSRVSRLLKDTKMVDKLREAEDADVLKILLGSP- +> +-GLLLANGIIPGLAAFSRDAVLMALARHA-ELGIPAIIVNEALRTREALGSTSFGGGVAIPHARL---AGLDQCQAALARLPQPIDWQSSDREQVDVVVLLLSPESDHLKALARISRTLRDPATLPAIRAAADAAAIRAIITGD- +> +-ECLDVNHIYVGIHLPGKDDVLAFLAEKAAGLAMDSGALLSGFREREDSFTTGIGLGIALPHTTS---AQCTKTTLFLLRLSRPVDFESIDDQPVDVVLALIIPTSEHLQILARTARLCKQQAFPEALRQSPDAGTLWETIRRF- +> +-TILTSQCTRAALAAPSRKRALQAASELLAQTPISARLLFDELMSRERLGSTGLGDGVAIPHCRM---PCK-EIQAAFLHLAQGVDFDAIDGQSVDLLFVLVVPTTAHLEILANLARVFSNPDNRATLRGAKSDAQLFEVMAGL- +> +-PYLFETGVLVLENVKDRDSVLRTAADAASITPISAETLLGLLLGREAQSPTGTPEGVAFPHAMV---PGLATSLVVLIRTGQSVEFGP--GRPCDLVFTMFGDAWEHVRLLARLARLTGRSDARDRLRAATDDASLYAMIQAE- +> +-DILTEDRVRVTRHQDGVKSEVLEALSLLLG-GQAAELIHKTLTDRESLQSTGIGDGVAIPHGSL---EALVTQTAAIVLCPDGVDFHSIDGRPAKIFVGVIGPRGEHLRMLARISRLLRDGNLRDRLLEASDGTQAFDVIVEE- +> +-DLLLGGPVLPALNCTSAKQVFSRLSSAMS-TGVSDRDILHAIVEREKLGSTAVGHGVVLPHARL---PGIQQPIGGFARLLTPVDFDAVDEQPCDLVFMLLASDADHLRALAKIARVMRHAGLRKDLRDAETEQDIRDIFCAS- +> +-DLLPKNAILTDIKKTDKNEVLRDMTHFMAYLNHDPEILTQKILEREAEISTGIGYGIAIPHVRL---AGIDRCYMAAARSKTGIDFNAIDDQPVHMLFMLFSPVTEHTQILSSLSRIMTWEEIREKLLQVDEAQEFLDVLTEG- +> +-VRLELAAVRDCQDIGNKSDILRTIARIGE-YRLDAEAIRTGLEAREALGSTGFGRAVAIPHAKL---PDIDHCIGIFLRLSEPAPFEAHDGKPVDLIFALLSPEVEHLKALAAASRFLRDDNMVAKLRGASGQDALYALLSKQ- +> +-NFLCNRCIIPDLNTKSKEEALVRLAQRVAEPDVNQDSVLSVLKEREQLGSTGIGGGVAIPHGKL---PEMSRMLIVIGRSPAGIPFDAIDNCPVHIMFLLLAPSISYLKILAKVSRLLKIQKVQQRIMEAPDARSIQKVIEEI- +> +-SFLTQQRTHCHLRLSSKKRALQEAATRIADPSLNSEDIYQQLSDRERLGSTAIGQGVAIPHCRM---PGCRKVTGALITLAEPVDFEAFDDEPVSTLFVLLVPPDEHLKVLALLARNFESEHYRRALTTARGDDELYARALYI- +> +-DVLTPEMSLCDLHWSSKKKVFENLAQFISLDTDRAEALFQSMVARERLGSTGIGKGVAVPHCRV---NGLNRVYGCLIKLNFSVDYDSIDNQPVDLIFALIVPDDDHEKTLAYVTKVLQRANSREKLRACRNNQQLFNTLIKL- +> +-GQSGVLRVLPSLKAASKKDVLAELLEPVLLGSIQASEVYQAIINRERLGATGIGQGAALPHALI---AGFANHLAVCGRSGAGVSFDAADGKPIHFFLLYLAPITTYLHCLAMLAGFLRSAHVQARLLAVRDAKAIQAILDEF- +> +-DLVGASHVVLQLAAEDKWRALCELCHIASGVGVGADVLLEAVEERERSLSTGLEAGLAIPHAFL---PGLPHAALIFAVAPSGIPWGALDGEPARLIALLIAPEATHLQVLASLSGAWVEPSRRAAALAAPDAAALRAVLSGT- +> +-GLLDRHSINGHVSVNSKRQALQAVADHA-LFRMDADVIFNALVDREKQGSTGVGLGVGVPHAAL---EGLTQMRGIFLRLETPIDYDSIDHVPVDLVFALFAPPSEHLRALAKVSRLLRQKSMREQLRLLDTNDALYALLADS- +> +-SYVAAELTWVMDGAGSCEALLAELAERIA-VGGDAAALLAALTARERQRPTSTPEGVAFPHAIA---EGVTESHVAVVLLGEAVEFDTVRHERCDVVFVLVGPPWLHVRTLARLARICHA-GGADRLRLATDDADLYRLLIEE- +> +-ELFSTDHVFLKVPVTSREQLFAFLSERA-LGLVNSQLCTKALHVREELGSTGLGNGIAIPHARV---EGLEKVVGLIATLERPINFEAVDGEPVDLVMMLLLPEGDQIKALSRIARVARNEAAVNALRRAQSVDEVTEIIEGV- +> +-ALTRPDLVFPDLPATDSQGVLRDLAGRVAGLVKNGEELFQSLWEREQLGSTGIGQGVAIPHCKL---KGLARGVVAVGLVPAGVDFGAVDQQPVKVFFLVVSPAAEHLQILAAISRWIRADQHAGRLLTLHDPAAVYDLLRE-- +> +-EIFRPEDVAIGVDAPTVKQVLLQAARLLASN-LPEAEIFKALVDRESLGSTAVGHGVAAPHARI---QGAGRAHAVFLRLARPIDFEAGDDRPVDLVCAIIGDYAELLRTLAGACRGLRNAETLAKLRQARNSGELYSMLIEE- +> +-EKLDASNVVLNI--EGRTQIIEKIIQQLHG-AFDEEEALEKVLKREELGGTGIGFGVALPHARL---NSAEDILVGLGISKKGIDFEAMDGQPARLIFLVLAPEETYLKVMARISRLMRKEEVREELLCCDIESDVASIIEKY- +> +-SLLNSNQIFLQLKSAEKEQFLENFISMLSEKTLNQSIIKDLIIKRENLCSTALDNHVAIPHAKI---PGIDKTYISLATCPEGIEFGSIDGKKTKILILILHPENRHLEILKSVSVLFTKENVINEILNFDNSQKLIEYIKHN- +> +-SQPQRALIIPALQATAKREALRELAAAACYPQLDPEQIRRVLEEREELGSTAIGDEVAIPHGKI---VGLEEMVLICGRSEAGVSYGAADGRPVHLIFLLLAPFNSYLSRLAELARFLRQPQVRSRLLQATSREEIAAILAGD- +> +-DCLPLENVVVNLSASSKRELIGKLTDVA-KTGADAAAILKAITTREELGSTGVGNGVAMPHAAV---AGLDASFCMFVRLPKPVEFEAVDDVPVDLVVLVLTPAGQNLNVLSCAARRLRDCNVLSAVRTARSAEEVFLVLTNE- +> +-DYLKLDDVMCDLEVSSKTQALHAMADVVSGG-VPAAALLAALQKRERLGSTGIGQGVAIPHTRI---EGVETPRACLARLKKPVEFAAIDDLPVDIILMLITPDNRHLNVLAQFTRRLRFPGVLEGMRTAADARTLCAHLTDK- +> +-KMIGKDSVLLDLEVKNKKQLLEDLSKYI-IISKEEREIFNILLEREKLGTTGIGKGVAVPHGKL---PKLERIHLLFAKTKKPIEYESEDGQSVDLFFLLLAPEADHLQALSEISKMARNRETRKTLREANNVEEIIKIFKSA- +> +-EAMKPDDLLLGVSASSKDKLLQLLSEHAGLA-VSEETILTALRSRESLGSTGIGAGIAIPHAPV---DGLVAPFVLLARLAKPVEFEAIDEEPVDVVCLILTPPNRYLKLLSSVTRQLRSADTLGTIRQAADRERVYRAFAEV- +> +-EVMQPNGVLIDVSVPSKFKLLKFVAETAALG-LVEGDVLNAVQSREDLGSTGIGAGIAIPHASV---EGINLPFVLLVRLTMPIDFDAIDEEPVDIVCLILTPSSHYLKLLSSIARQLRSVDAATTIRRAADREIIYQALITC- +> +-EILTPKRCHNKISVTSKTRLLSTISNIIANKSLDADTVFCSFVERERLGVTSLGKGVAIPHCKI---AACTKITGSLITLENPIDFGASDGQPVDLIFALVAPNKQHDNTLAEIAKLLNDDDFCFMARQTFDNEDLYNVTIMT- +> +-DILLPAHVVVGLRCSDRAQLISELSSIA-TVALSQGLLSGRLLERERLGSTGVGDGVAIPHARF---EELAQPFALFARLQRPIDFDAIDGKPVDLVFLLLLPAREQLPLLASVARHLRQQAIARELRAAADASTAFQVLTRA- +> +-DMLAPDAVLLHLKAST----LDDALQQISAVTGLASPLILAALRERTAQGVGMGHGVALPHARL---DGLRRVAAFFARPLAPIP-SPDGGEPIRLIFILLAPQAAHLKALAQVARVLRMPESRMALEQAPDKNTAYALLVAA- +> +-------MVRVGLEAVDRLGLFRALVGDLAEEFQNQQAVFDAVVHREGQRSTAVGEGFALPHATS---EHVPGLLMAAARLARPIEFEAPDKEPVDLVFLVLAPPAPFLVLLGRLARVVSRKDVASDLRSAPDEESFEAKLQEL- +> +-DYVDEKHVIFIDEKLDKDALLKLFAEKFRELDAISQAIFEALYERELLSSTAVGEEVAIPHAKL---ANLDDIKMIIAISKVGQDFQAVDNLPVKLFFVVIAPAQLHLKALARISRLVKMTDFKKRALEQDSAKKVIDILVEE- +> +-IFDDPKTILVIEEDFEKNQLIRKVVEYAHAINIVEEAAYNAVIKRESMGSTAIGDGVAIPHAKL---PFVVGINIIFCYLPNGVDFDAVDHNKVRYLFLILSQETLHLKALAAISKLIKNTGFINQLSGEMELIRIHSILKEC- +> +-KLFKPKSCIAKLKAADKDDALREIVTQLVKSLDAEDKAIEALRDRERLASTGVGMSVAIPHVKI---PGLERAACSIAIHPEGLEWAAVDGNSVSIFFTVLRPAQAHLEMMSWIARLGRDADFRRFAERARTKTELVDLLKEM- +> +-DVVSEDLILPSLQGIDASSVLKEFADAICSTGKCSQALFDRLYEREQQESTGIGNGVAIPHCKI---DNLKDVLVGIGYSESGVDFNALDGKPIHFFFVVVSPSVMHLRTLAALSRLLKSQNFLSYLRQRPKADLISRIKKEE- +> +-DYMSPEQVYLDAPIRGKEEILHFVSQAFAQCGAAPRTVYDCMKEREDIMSTGIGGGVGIPHAAC---AGVTRPAVVIARLARPVDFQALDAHPVDVIIAMVVPNSLHLRLLAAISRLVKSTNFLDDVRSASSSGDLFSHIKEI- +> +-PFLQQEHICTAVDATTRDELLRVAAQKINSVCADLQTLFQALWEREELGSTALGSQVAIPHCKI---EGLDQIRLFVFTSARGIDFGSPDGQPTSLFFVILSPPSEHLQVLARIARLTRSDGFVSDALAASDPVRILQCIEQY- +> +-DILKKDSIIANLVGTKKEEVLHEMTDFLQSQNLIQETLFKTLTEREKLGSTGIGENVAIPHGKT---DEISQIITVFARSLGGVDFEALDQKPVHFICLVIAPSGQHLKALARISRIFKNQNLRDNILKLQDASQIYSLLLEE- +> +-EYLCPACIVAELKATDKEQVLLELAAAA--AGAHLNAVHAVLLERERHGTTAVGNGYAIPHGKL---PGLDRMVLTFARSVAGVDFAAPDTVPCRFFFTVIAPAGQHLGLLGSIARLAKDATFTNRLTQAKTAEDLLDFLAGA- +> +---------MVEFNAPTREGALNALVHHLLKLKLIEEELYQKLLEREMMESTAIENNVAIPHCKL---EKLKNPVILLGISRQGVNFLSIEKKPTHVFFLVISPAALHLKVLASVAKIAKSKDLMKKIIAEKDYSRIKQLIKEE- +> +-ELLAEGVILCPLEETEKWAAIEECVQALPHVASRKSAM-AAIRERAQEHSTILDNGVAIPHGIL---PDPAPLAGALGVSPVGVSYGVG-ARKAGLIFVIVGSRREYLGILAQIARLFRGLDLKNKIMQAKLPGDVLQLIRDA- +> +-ELLKPEAVLLDLEAADKWQALEQICAHLRGAGLLPSSILALLSEREQSMSTYLEHGVAVPHASA---IELGQEVVGLALSRRGVPFDSVSGEPAQIIVTLITPRLLHIRTLAEVARLLSHGSVRKSLLESDSPEKVLAAIRRG- +> +-ELLSEKVILTNFKAGTKLDAVGRLVDVIIASGDIPQAVLDALIARENICSTGMEHGVAIPHATV---DVLERPAAAVAVSLEGVPFQSADGKNATIIVLLIITRKHNVRTLAGIARLLNYEDTRQHLLVAKTPSAILDVIREE- +> +-TLLTEENILTGLSAGDFETALTALVRALPAWRVGPNRILAQLVSRERLGTTATGGGTAFPHCFS---ADIAEPVMVFGVSPDGIPYPSLDGHPVHFVFMLILPEAESRSLLQNVRWVLCDRSVKERLRSAASARDVLAILAPH- +> +-ELYPPPSMLLDLQARDKQSANEEMLEHLVSQGTLDKDALKAIKKRETQASTGIGKGLGVPHAKC---DFIDGLLGVYARSAEGLPYESVDGEPAHLLFLVLSSQELHLEIMKRVATLHRDEKSLRYLAKSDDPKRITDIFREA- +> +-EILTPKDLHLGFNPGDKWNGIRILVENLVAAGRLSADVLEDVLEREHSMSTGMEDGIAIPHAAV---EGIEEVLATVGFVDAQLDFDAVDGLPTQVVVLLVIPRMLHIRTMAEVARVLGDQELLARLVACGDQDEAYTLLTSA- +> +-HLISPECIILQLDKTEHEEVVLEMIGHLSEIGKIAYRYSQAVMERESQTGTGLGAGIAIPHARV---PGLKEEVAVYGRSGEGVDFESPDQGLAHHVCLLLVPESNHLKILRELAKVFSQADLREKISSAQSAKEISELLCIG- +> +-KLLEEKRIISELRSSNNQEAIEELINHLCDNNFLPFETIEKLITREDKTTTGIGSGVAIPHITS---DAVESTLMIFGRSTEGLDFESIDNNPVNFVILFLIPTNKHLQTLATIARFFTKGDIRERLLKATSNTEILRVIENH- +> +-ELFEAQDLLVHFDPTDKWEAIQSLVQYLVTTGKLDEAVLEAVLSRERSMSTGMENGIAIPHAAV---DELDSVLACMGVVTEGLAFESIDGQPARFVVLLVIPRLLHIRTLADVARVLSKEDVRGALLDAADQEAAHQVLVQS- +> +-THFRSGSVLLAPLVTDKWNLLENMVDSLSSTWNLSNLCLESVLERERCVSTGMEAGIAVPHAAV---EGLDKMVVSMAILPGGLDFESLDGQPAQIVVMILVPKLIHLQTLTEVARRLGDASFRTDLLAAASPEAVIQLWS--- +> +-KLLKIDSIFHDLECQNKIEYMKIISKIMEKKSSISKTIFNSLYSREKIGSTGIGNGIAIPHGKI---KEFQSPILLFTKLKEPISFGSIDNEPVDLLLSILISKKEYLSMLFLIAKELANENSCRKLRKAKSKYKIYSILKKM- +> +-KDITLDYVLYGLKSRNKREVMRDIARFVSKQGQMDVALFDQLLDQERQASSAIGMGLAIPHIRL---NDLKTPLNMLVHLDKPVSFDSPDGEDVQAIWVTMSPRPRHLMRLAKISRMLNNPQLAKQLKQARSLDELRALLFNV- +> +-QLLSPESTQCCDKTNSKKKVLEKISEMMANSIDCKQSIFESLLNREKLGTTALGDGVAIPHARV---NHCKCATAVFLLLDKPIDYDAPDGKPVDIIFAILVPENSHLEHLQKIAKLLSDSKIISQIRHAHCDEALYDILEKA- +> +-DFIDEGLICCNIKPESKSILLENLSKRICQKSEINTSLLENLLKREEENSTGIGNSIAIPHCIE---EKINKTICLIAQIPDGVDFDAMDDKKVKIVFLLISPPSEHIRLLARITRIIKDRNVVTSLIDSKTNQEILNILLQE- +> +-AKLADLLVFSQLSVHSKKRVFESAAEAFCDVSGLSEAVYRGLLDREKLGSTALGDGVAIPHCRI---DECNAPLGCLITLSNPIDFSSSDGQGVDIVLVLLVPSKEHLDLLAGAATLLSNEQTRLAIREAVEPVDLTEIVVKS- +> +-DILTPGLIFNNIKSNQKDLCLDEIIKNICSFKSLNELTQKLVFEREKLCSTALDNYIAIPHAKI---PGLTKSYCALAISKNGIDFGSVDGQKTKIIIMLLHPEKNHLLVLKNIANLFSIKELILQIIDSKDSFDIFNIIKKY- +> +-DLISQNNIYLDLEVESKKTLFKFIANKISHLIKVDNLILQKLNEREKLGTTSLGNGVAIPHTKI---DGQEGVFALLLKLKRAIRFSNDDPKNVELVFVVIAPETDHLLALSVISKFLKKKNIINRTCKAKNVGQIYNLIVQS- +> +-DLINEKNLIPNLVAKDRSLAYSSMLQVLLNNKEDITSCLEGLKAREAKMTTAMGGGFALPHATI---PKLAKPCYLLARCPEGVECEAVDGKLVTLFFLILTPPQEHLQTLATVAKFFNRRGIKSKILQAAGIPEILSIIRPS- +> +-DLLPTQNIRQGILCSSKKRVLEVIANIAAEHQNLEHLCFEQLCAREKLGCTSLGGGVALPHAKL---AGGEKPVAVFLQLDTAIDFSAADRRDVDLFFALLIPEDAFKIHLARLAECLTDKSLCKQLRNAQSAEEIWEIFEHI- +> +-QFINENSIFIDFKSKSKKNILENISHEMSNGNTKEDLIFEKLYEREKLGTTAFGNGIAIPHARI---PDLKEPKVIIIKLLDAIHFEAIDGEKVDLIISLIVPDDLHVKLLAKIAELLENKTFRLKIREAANVKDILSVVKNF- +> +-EFISLESIHVDIDIDSKKNLFKLVSNIFSKNDTDKSIVTEKLNERERLGSTGVGNGVAIPHSKI---SYIQKTKVFLFKLKSAIDFSASDKKNVDLVFVILAPKSEHLLILSSISSFLKKEGLVRKLRTFKKAEEILKFISKY- +> +-SLLSPKSVLCKHSSSSKKRLLEDMAEYICKQTELDNTVFRALISREKLGSTSIGNGIAIPHCRI---PQCNKTIGMLVTLDQGIEFNAIDNQNVDIIFTLLVPEDKHLQTLACIAETLSNDVILNNIRHAQQSEELLQVLQ--- +> +MDSDVKCAAFIDVKVAQKEAALATTAELLANQWSIDKELYASFVNREAESSTGFGDGIAIPHAKV---SGLEAPVVGILTYADPVEWAAIDEQPVSLAIALIVPTQVHLRLLSKLARKLVDHDYAEGLRRSAHDAQLTKQVQQ-- +> +QELFNLNHIYFDVDCKQKEAFTFIANAFVENDVSNNKKCFKGLVKREKEGTTGFNDGIAIPHARI---KEISRPGLFVFLFKDGIEWKSIDDSKVKLAIALAIPESEHIKILSSVARKLVDQEFCQNLLSAKSKEAVYKLI-S-- +> +MKEFDLQNIFTDVTVTNKNAALQKMAELFASKNQLDKALLKGFEAREQESTTGFGSGVAIPHTKI---AGLKQPLVGMTTFTQPINWESLDEQPVTIAIALLMPIKAHLSVLAKFARKLMDEQFVADLQAARHQASLYQVVTA-- +> +NNVFTPEHILFDANSTQSEALAFIATEAKKLNIIDCESFTKGLEAREAHDSTGFIGGIAVPHCKS---KHVITPAIFVVRFAHSIEWNTMDDYPITTAISFAIPEEDNLRMLTKLSRAMMKMDIRQALQQGDAKTVTETLL-N-- +> +ANVFSKANILFDHDSQQEEAFHAIAEHVNKLGYADSDSFFAGLMNREKETTTGFKNGIAIPHSND---ASVKRPGLFVIKFDHQIEWNALDKKPVQVAIALSIPQKEHLRLLSKIARKLMDEDFTKTILENDDPDILAQAI-N-- +> +MEKLTEKDLNFDLKADQKEALHALAEQAFERGKIADEIFYQELCNREKESTTGFGNGVAIPHARH---SVVQEAGILVARCKNNLEWNSMDGEPVNVCICLIAPDDFHLKTLAKISRRMIHDDFIETLKNASEADVL-AEINK-- +> +-EIIKEENICIDLKSKTKKEILKELISLVKTGEILDEKLYNDLVAREDAGSTALEHGLAIPHVRS---NHIKHFSIGLGISQEGVDFESLDNEKTKLFLFIATPTNWHLEALAKIAKIFYSKTNVNVVSNCKSKEGIINLISKL- +> +-KIFTAGSVTVDLHGGNKQEIIRELMLLMVSSGRVREGVIDAIVKRELRMSTGMQDGIAIPHAKS---KAVKSLAAVLGIKKNGIDFDSIDGKPSTIFIATLSPEIPHVQFLAEISKRLRSANFRTNLINSNSDEELLANLIEG- +> +-NYLSLDNIVFKIKADKKEDIIKELLENFSKNDDVIDVVLNDLYERENLSSTGMQDGIAIPHAKS---SGVKKVSMVVAIDKDGKDFASLDEKKSKVFFLVVAPEREHLDILSVISKLSFEEEKLEKLINSTDKHEVFEILESL- +> +KNLFNKDTIYLNKKFDSKSEVLEFFASELVSKGYGSGKILELFQTREKQGSTGIGDKIAMPHLGD---DVISKSTLLFAKVN-NLEWESLDNKPVDFIFGIALSKSGHIEVMQKLSTLLINEKFVSELRKVDSADAFVDLLDQF- +> +QQFFNKDLIFIDQEIKNKTEAISFISLKLKSNNFIATQTQSEFSSREEQVSTYLGDFIAMPHIRN---KNVVKNSIMFIKNSKAISWNNTPQEEVKFIFAIALNDDLHIQIIQQLSKMFMQKEFLQKLEAIKTQKEFLQLISRF- +> +QDVLRQDVMLLDLQARTKEAAIDEMITSLAEQGLISAAFKAGIMAREAQTTTGLGDGIAMPHSKN---RAVKEATVLFAKSNQGVDYESLDGQPTDLFFMIAAPEDTHLAALAELSKYLMKPGFADKLRRVTSPADVIAVFDKA- +> +ADLLSPQRIELNLPLQDKQAVLERLVKLEGYGEAILEAFRRDMMAREAQGGTAVEAGVAVPHAKS---AAVRYPSLAVVTLREGIDCGALDGVPSDIFFMIAAPAELHMAVLARLTRLLLEPEFLEQLRQAITPEEFLEIVDEF- +> +KDLLKRNLMIMELKSSNKMDVIDEIAQKFFDEGIVGEEFKEGLIKRESETSTALGEGIAMPHAKV---DTVKEPAVLFAKKAEGLDYEALDGEDSFVFFSIAVPNNLHVQTLAKLSKMILKEGFIDKLKAANSPDEVYEIIDSY- +> +TELLRENQVIFNLNADNKKDAIIEMAKV-FKPDVINEKFIEDLFARESLSHTALELGVATPHAKS---RGVSKPALVIAIKKEGIDFSEGQEDKSKLFFMIAVPENLHIDILTKLADVMLDNDKLNALLNSTSYDEVIDIIEKE- +> +-GILTIDRIHINVTISSKKRLLEELAISLSSSSLNKDTVSRTLTERERLGSTGIGGGIALPHGRL---NGIDDCIAAIIRLREPLNFDSPDAQPIILAIGLLVPANKHLKILSSLATMFNDSEKRKSILSVEDPSTLLKFLT--- +> +-ELLSPATINLDLQSTDRNAVLAELVNQIPQFANPRQTLLNALYEREQLHSTSIGDGVALPHARNAIVGLVDQPIIVFGRHPKGIAYDTLDHQPARLFFLLVAPTTQHLAILARFNRLLRDPQLRQALLTAATPEEVLSRIRES- +> +-RAIQSGGIYYRIEGNDKATALASVVKMM-HLPEVREFLLSVLLAREEIASTGIRDGVAIPHVRNPIVLQVPEPTVSLCFLENPIDFKAMDGKPVYCLFTIISPTRAHLHLLSRLSFSLRDSQLKKAIESQATRETICSHIARV- +> +-EAIKKGGIHYRIEGKDKKALLNAVINLL-NLPDVKETLLEAMLVREELGSTGFGDGIAIPHARYPVVTHIPSPVVSVCFLDKPVDYGSIDGKPVSCLFTLISPTRSHLAMLSRIAHVLKDAGVKNALVAQKNRDFILTKIEKA- +> +-SLLSPRLVM-FLGKHSRDEILQDLTDLVDAAGLLEQAFFDALVRRENIMSTGIGMGVAIPHGKL---ESCSNFFIAIGIHTQGILWDAIDGALVRLVFLIGGPEAEYLKLLSTLTLSLREESRRQQLLQVNTIEEVMNVFVG-- +> +-DFITPDRIL-FWGKQTRNGAILRLIDRASGLGLADDAFEHAVMQREKISPTAIGMGVAIPHARL---ASIKDFFVVLGVAKNPIEWKSADPNPVRLVFLVGGPDEQYLKIVARLMLLAKSSVYREAILKATDPKQAAEQLRA-- +> +-NYINNKLIT-IEEI-LKPKLLEKLIDMVDKNELLLDDFAKKIFDREEIGTTGIGRGIAVPHARC---EKLNNIVLAIAILKKEIEFNTPDDEDVKIVLLVGAPKKEYLNLLSNISKIFRNNEFREEMLKAENKEDVFELMAS-- +> +-EILSPERIM-VLEESNQKEMVEKLLTMIKGSPLIKDTIKDAIWEREKIISTGIGLELAIPHTRR---EDIKGFIASAVLVKKGVDWKAIDDKLVKFAILVCSPSKQYLKLLAQTVLLWKDDYKRKKILESNDPFQIYNILKE-- +> +-QLVQKAPFT-LLQTKDRDKALKTLVDSLLDKGSVIKQFYTALLERESLISTGIGLGIAIPHARI---EDCKDFFLAIGIHKSGIEWGSIDALPVRIVFLIGGPKGDYLELLALITTFIKDFEIKEKVLNTSCHQDMMDLFS--- +> +-DYLSESSVL-FLNNSDKNEVLAAMVAHAASSGLIPNSFKHAIFEREAIMSTGMGLQVAIPHAKL---PEIQEFFVIPAILSQDSNWDAIDKRPVRLVFMIGGPSTDYLKILSKITLVIKNPARRKALMAAKDAKAVLAAFAE-- +> +-RLISPGRIT-RIDEDNKDDCLRSLVKCLSESESLGDSIFEAIMDRERLLSTGFGLGLAIPHAKL---NIIDDFIVGLAXHRDGVPFDSLDDQPVHILVMILGPDDEYLKVLSRVTAFLKDQ--REKILSLEDNEEIXKLTFD-- +> +---MDVNNIV-FLTKKNRNDVISELIENLYKTQKIKNIFFDNIIKREKLFSTGIGMGVAIPHTKN---GDFENFFIAIGIQKNKINWLSIDKIAVNIVFMIAGPESEYLKILSKLTSLIKNESFKNKLLKFEFKEDIFAFFDQ-- +> +-QILRSDCIILDKQLQTKKDVIDYMANHLYQGNYINEKFIVDINKREKESSTNMGNLIAIPHAKS---SSVKQPVMMYLRTDKEIDNDG---QKLRSFFMIAVPEDEHLKIISKLATYLMDENLLKHLLSAETPYEILNIFNNK- +> +-NLFSKNLIVLNYNAISKEDVIRKMANMLNENGYLNETFIKEIKKREEINGTGIEEHIAMPHAKG---NFIKKHGIAILRVNSDGDFNSSDQKLSKLFFMMALPENAHIKAISYLSNTFSNNLLRHELMSTNNTNRFLEILMSN- +> +NRLFRPELVRIVDRFADKNACLEYMSGMLSETGCLSDRFFAAVKGREEIMSTGIGRGIAIPHARD---LTVSCLQIAVCMTREAIAYQSIDNLPVRIIFMIAVPQQQYMRILRSLSEYLRQEENRQQILKASSEEELFQYVHK-- +> +TDVTNEKLVMIDTEFNSKEECIDALCERLAQAGKIKDDFKQAVREREDLCSTYCTMEIAIPHGIT---STVLSSSLCFLKNKQCFDWDGDGETPVRYLFLIAVSGNEHMAILSKIATLTIEDDFRAALADLKSADEFINLLNG-- +> +-MLFDKKLIRVNAETKDKWDCLKKMAHLLALNDILTDEFFASVKEREEFISTGIGYGIAVPHGRS---NVAKSLAIAVFHLKNTIDFNSLDDKPVKLLFMVAVPESEYMKILSAVSKFLHIPDTINNLFSVNSVDQIYEILKG-- +> +MSVFARDLIKINYYALDKKSCLTEMSEFLFEHGVIKASFLKDILERESLMSTGIGRKIAIPHTRS---KEVTQLKIAVYLLDNELEFDSIDGELVKIIFMIAVPEEMYMKVLSVISNYFRNDEKRDKILSCNSKDDLFKLLKE-- +> +-------MINIDNKSVSKNEILKIMVNMVENSDLISDIFYKEVLERENVGTTGIGMGVAIPHART---EVVKDIVVSVALLKRPVNFDSLDGEKVKIVILVGAPKKKYLELLSSLAKIFRDKKIRESILESTTTECLIEAIAE-- +> +NEFFKKDLVVTNKSFKDKKEALSFFANLLVEKKYAKETVLNKALERESQFSTGIGNGLAIPHIRD---DVMNKSVILFANI-KPVNWESLDNLPVEKVFFIAMSSNSHMDVIANLSKLFMNQEFVDKLAKVNSYDSLIKLINEY- +> +ELFF----NWTAKDFKDKTSFLKQACRVLQDKNCIKQIALTALKEREAQITTGIMSKLALPHMQS---ATVLKPFVAVFKV-NNVDWQSLDNQPVKLIFLIGVPKNLHLEFISQFSKLMLQDEFANKVPNIRSFNGLINLIDSF- +> +SALITANLITLDELGDSRFDVIKHLTQAVVNAGRATETLYAAARAREEKTDTGIPGGIAIPHCRS---EAVTEPTLAMARPAPGVDFGAKDGA-ADLIFFIAAPAEAHLKILSKMARSLMKKSFTTALREAKTRDEVVVLVEEA- +> +TDLLSASRMRLHVAVADKQDALDQLIALTRQDGLLTDAFRRAVLEREEQVSTAIQEGIAVPHGRG---ASVRRTGLAVMTLNRGVEWGAMDGQPSDLLFLIAATE-SYMEILSRLMSLLMDREFQKQLRAAATPQEFLDAVDKA- +> +TELMDLKGICVGISLKEKDGVIDILAALQQKCGNIEKILKQDIFYREEQGSTAIGAGVAIPHVRS---SAVKHAGITAVTVPAGVDFEAPDGEKSRLIFLVALPEEN---PLSKLTVLLMNEDLREQLADAANEEAFLELLRLA- +> +-QIFPKETVVVNLQSTEKDELFEELVEAIHSHVPGDNEALENLREREAKMSTGIMHSIAVPHALI---SSVKETVGAIGISRDGIDYDALDKAPVHVVFMIIGASEHHIQVLKQIATVLQIPGFVDRIRKCESAGAVHELICKS- +> +-VFFDNGSVVWELESETKYDAIHEVIYPIFRNLPGDDQFYQVVHHRESLQSTGFGHGVAVAHGRT---PMVADSVVALGVSRQGIDYQAMDNRPVHLLFVVATHPLNYLKVLSSLITLVRQESFRREIFACLCQEEIEEKLCHG- +> +-ELFPENRIRTDIASVDKESLFVELVDLIGLTSSGDGAALGCVMEREALMSTGIRHGIAVPHGKC---DAFESMVGAIGISRSGIDYDAFDGCPVHIAFLIISPRETHLRTLKLLAEILDLPGFVDALKSASSPKEVSDALELF- +> +-KVFNKDAINTDLKSKTKQDAFEELLEAIQNVQPENEEALEALTARESQMSTGIMPHVAVPHALC---PSARGAIGAIGISRSGIDYNALDGSPVHLIFMLLANPSQSLRVLKHLAQLLDTPQFAADLIRKRTVEEIQGMLNLQ- +> +-SLLKPENIILELESSEKDVLFAEMVENIVTTHPSNSEALAALTERENKMNTCIKSGIAVPHASC---ASVTYPVVSIGISRGGIDYEVEGGSLVHLVIMILFEQERHLHILAECAHILQTPAFYQTALTAGSASEIIEKLRRI- +> +-ELFTPARIKVRVEAEDKDEVFEELVDLLVTQYRLSDEVLDAIRRREAKMSTGIKRGIAIPHAKT---ALTKGVIGVIGISQGGIDYQSLDGEPVHILFLLVSSEGLHLAVLKKIALLVENPDFYAAVMAAADAEAVYKALNRF- +> +-EIFKVDNIKINIESEDKEELFEEMVNFLIDAEKLIEEILTGLKKREAKMTTGIAPHIALPHTHI---ANIEGTMGVLGVSQAGIDYDSLDGQPVHLVMMLIGKDEGHLKVLRNVAMLMSNPDFYPSLIKCKTPAELHNTIVEF- +> +-KLFSAKNIKLNLESTEKDELFEELVDLYVSNDSSSDSIIDAIREREAKLSTGIKKGIALPHARI---SGLKEPRGIIGVSKKGIEYDSLDGNPVYVVFMLLSTVSLHLKILNRLNILLLNPKFLEELFRETSREGIYNMICKY- +> +-SFITPSSIKVALESSEKEESFAELLEVLVAKHPENKEAMNALITREEKMSTAVFPYVAVPHALC---SSAGDTLVAIGISRQGIEFESPEPPVVNVIFEILFEEQTHLDVLRDILQLVSNPDFVKNVLQAKTSQEVYELIESM- +> +-DYITPSDINLNLESTDKEEAFAELTEMLVKKCPGNTEYMKAVTERENKCSTAVFPKVAVPHAVC---DSASKTTIVVGISHDGIEFEPLESPVVNIIFQIVFERGSHLNVLRDILYIVSKPEFYEKILTLKTQKEIFDLFTEL- +> +-TIFPQDRICLDLVDTAKPELFAVLVSKLNQTLFRDMMACNALQVREARLSTAIGNGIAIPHAKI---TGINEVLGVVGISRTGITYKASDDKPVQLIFLLLSPADKHLHALKLLATALEKTTLRDDILAGSSDTALWRCLQAA- +> +-HLLTPANIKADLESTEKDEVFEEMLEMVVASQPSDQDALNALMLREAQQTTGIIPGIAVPHAQC---ASVRGTAIALGVSRSGVEYDSLDGSPVNFIIMMLFAQESHLQTMKDVANLLQSPDFLKTIMEKKTPQEIFDAVCNF- +> +-RILRKDNVVVDLQSRRKFDVLRELSAVFDNDDAIDKQFLADLIRREQQGSTGIGKGVAVPHAHE---DSILRQILAIGISREGIDFDSADDAPVHIVALLGTPRKQHMELLAELSRLLQQDQVRDDLVAAASAADVLAIFKSG- +> +-ELLQPPFLKVGLQAKEKEDVFEEMLDLFVDRGLIDEAALQALFEREAKMSTGIAKWLALPHGKL---EEARSLMMALGVSKTGIDYDSLDGEPVYVVLMVFAEVGPHIEALAEISRLFSIPGFISEIRFAETAEAILDFIRKE- +> +-QLITPDCVFCAVPAKSKKRILQVISQYAAKQLGIQQDILDALLAREKLGSTGIGQGIALPHGRL----NCNKSLALLLTSDEAIDYDAIDNAPVKVFFALLAPEQDHLKSLALIAEKLSDKTVLKSVKNAITNQELYQAIT--- +> +-SILTPERTFANLESTSKKRVMEQASGILTGAEPISQHLYSKLIAREKIGPIVIGKRISKPHCWVE-----SNTFAALFKLSRGIDCSAIDEIPVRIVLVVIAPQNTHLEILAMLASKFGSPVF-------------FEAVF--- +> +-NFISPDDLFIRLKANSKKQVLQEMVKLAASRASIDREVFDLLIDRERLGCTGIGKGIAIPHTRCS---LAVNPIAILATLDKAIDFEASDDEPVDIVFMLLAPDGEHLTVLALASRLLSTEGIADNLRKATTVDEAWSAIL--- +> +-ETLPIDCTRADISVRSRKHALEIAAELLAKKEFLTRYIFDAFMERERLGTTNLGNGVAIPHCRLN---CSR---SSFLIFSDSINYDDSEQDNIYMLFALIVPTDLHLELLAKLSAIFSDSKNREMLKSSTTDGELNNTMI--- +> +-QLLSPDAIVCNATGTSKKRILDEICEKAAQQIHLSHELLMCLIEREKTSSTGIGNGIAIPHGKLP---CGNQPTAVLLTSESGVDFDAIDNRPVDIFIALFVPENQHLSTLQDIAKMFSDKQFCKLIRQCDSSEALYELLA--- +> +-TLITEDSVFSQVNCNSKKSALEKISLSAAKKLNLDQVLFNELIAREKIGSTAVGSGVAIPHIKIP---SDLPATGIFLQCQKGIDYDALDGKPVDILFAIFVPEQEYLSALASISAKLLDKTLLRQLRSATDDNILFQYLQ--- +> +EGLTRADLVLLDVVATDRADAVRQLTALLVAAGRVTEAFTAAVDAREHQMATGLPGGVGLPHARS---DVATQASLAVGITGKRVDFGSTDG-PADIILLLATPASLHLEVLAGIARSMAQPNVRESLRRAYDVEVIAELVNST- +> +QAITTAEMVVLEFAAPSRNDAVAALAATLVETSRVLDGFLSDVRSYEHQLATALPGGVGVAHARS---SHVVLPSIAVGVLGNSLDFGARDG-DAHVVLLLATPASEHLTMLAALARSLAKDSFRESLRRSHDPEVIAELINST- +> +GDLITPALVDLHLDAVDKVAAIRALACRAVEAGRAGEQLVLDLKVREEQLPTGLEGGIGVPHARS---ATVTEPTLVFGRSDAGVPFGAEDG-PAHLVFLIAVPDDCHLAILAALARRLVQSSFKDALLAALEPEAVVDLVRRE- +> +NKEKVAIVTRLQLDAADKKTAIKQIVECLNVENFVTAKFVKEVFERESILPTYIGHEIGLPHSQS---DSVSKPVVAIGRLMNPIVWNDE-N-KVKLIFLIAVPKNIHLKIIAKLSRMLMHEDFRQILLVEGDEKVRKTMLEEG- +> +-NLLVLDNIVVPMKNNNKSQILNELAERFVQSGNAHQELYNHLQEREHKDPTIVEENIAVPHAKC---VCIDKAGLVVGITKEPVVWNEETQETVRLIFMIGVPENLHIEILQTLGTILNDEYLVKKLLNASDSQAVWDVFKNL- +> +-KLLTAERIVLDRVPADKAALFTLCAQKMAEQKRPSQAFITLLSEREKKSTTNVGEGVAIPHAQG---DIITEPTLFLFRPDVGLRWDETDDEPVVLIFMIAVPADQHLEIITRLCRWLMDDDFRQGLQTAPDAEAVLALLQSK- +> +-KLIDKGF-IKILKATTKDEALSELIDLLGQRSEVKAELKKMIFYREKLMSTGIGLGIAIPHIRV---AGIEKPVVVVGLSPSGIDYESIDNQPVRVIIMIVAGAKEYIKILSQIVSLLKNEPVRQQLFQSRSIDEVYNILIK-- +> +-DLVDAGL-IKDLDSVTKSEALDEMIELICQSERIVAAFREAVLARERLMSTGIGLSVAVPHVKI---SAVSDYVVAIGRSRSGIEFDSLDSQPVRLIFMVGASDGAFVKLLARIVTLIKNGTTRLALLEADDPEGIRDALLA-- +> +-SVLTPKL-VCFLECSRKKEALEKMIDCLCANSEIRNELAEGIFHREELMSTGIGMGVAVPHVRL---ASIKKPVMCAAVCRNPIDYESLDGAPVRLIFMIVAGKAQYLRLLSSISSKLKNEKLRNALISASDAETFCQILSG-- +> +-RLITPDS-ILLLKEAGKTDTLGQLVSSVPEAASSLKEILEKLLAREELMSTGIGLGLGIPHIRA---AGINTPVLRIGVQPKGIDYESIDGLPVKILFMILLKEREHVALLSEIVSLMKMEHLRNQLAAISSAQQGYDLLRD-- +> +-DAIEKAV-LLELKAGTKDELLKALIGAVGRSSRVKAAAREAILEREELSSTGMGYGVAMPHARV---KSVTFPVLGFARLAGGVDYGSVDSEPVRLVFLLLTPAELNVQLLGKISRICQREDNRRRLLGVEKTGDFLTFIRE-- +> +-ELLNKDY-IIDIRSDNKEGALKELLDVICKNERITKTFSREIFNREKLMSTGIGYGIAIPHARH---KTVKDFVIALGRKKEGLEYESIDDKPVKLIFMIGASDKDYIRVLSRLMLRLKNPDFVKKLLKNLSMLSTRLLFLF-- +> +-DVISPER-VMILESASKAGVLRELTNLLTATGIVAGELERLILEREALMSTGIGLGIAVPHARI---AGLSTSCIAFGISPEGIDYESIDGSPVRIVAMIITGTREYIELLSSLARLFKDESTRERVLSARTTKELWETLMH-- +> +-TILNPEQ-IIDLQGGTKDEILHELVSLASQDSNVTQELLAAILERESEATTGIGYGIAVPHAKI---SSVLDTVVVLGRSKNPVSFNSLDEQPVSIFALIAVNNKEYIRVLAKIAQFLKQEVNRENILAATNTSDVANLVKN-- +> +-QYVTKDS-VMSLDGRNKLEVMDQLITRAADL-TKLDVIFRLTWKREQMMTTGVGGMLALPHIRV---NDINHPYVIVGVCENPIDYQSQDDQPVRVIVFTVAPDEAYLQLLGSISRKLRNTSLIQELVDAGNPAQILDLVHR-- +> +-EVVKKEC-CFRLNENKKTEVLIEMMECIHQKGFIEENLKKEIFYREQLMSTGVGMGIGIPHVRF---KGVEKPLIAIGIKEKGVDYDSIDNEDIKIIVMIMVGEKEHIRLLSQVIGRMKDAGDREKLIHASDSEEIYNLLTG-- +> +-EYLTPER-VVVLKSVTKADALGELVDVLVATDGGVEELIKEVWKREDLMSTGIGNGLAIPHVRM---SGIRLAAMVVGVSRAGIDYESLDKKPVHIIVLIAAPEETYIRMLAKVADVLKEDTLRQAAIEADEPATIHRILTE-- +> +-KYLQPES-ILILDGETKKTALEEIISYATTR-CTLAQLREAIWKREKMMTTGIGNGLALPHIRV---AGFPSPLVIVGLCQNPIDYRTLDNEPVRLIVFLAADEEAYLKILGSISVKLKDKDVMAEILEAPDKKKIFAILNK-- +> +-ELFNTEN-IKIVEQSSYDETLSMLLDILKNSEKIKEKFKSAIYEREEIISTGIGLGLAIPHARR---DFISDFAVSAVIINKGIDWKSIDDKPVKMAVMVASPAKEYLNLLSRIVLMWKNTGKRKRIIAAQTSEEILDALKD-- +> +-AWLQPQEILFDVDVRDRPHALEVAAEAICRARLDPAPVVRALWRREQAGTTALGDGFAIPHACI---GGISQPTTLFIRTRRAIAFHAPDGKPVSQLLAIMVPEDDHLQLLALVARLFTDHSFRAQLDGAPDAAAAAEVFRAG- +> +-DLLKDQDVLIDLDVPDKDALFDVASQGLANGCISAQNILAALTRRERLGPTALGQEVAVPHASV---EGLDGIHVLYARLKQPCFFDGATGMPVMHALFLIVPMQTHLDMLAEVARLFSQPDFQKALRRAESPAGIRQAFQAY- +> +-RILPQENILLDVNVTSKKRAFEQAALLFENNQIARSTVFDSLFSRERLGSTALGHGVAVPHGRI---ANLKQAVAAVMRLSTPIPFDAPDGQHVQLLVILLVPEQQHLEILAELAQMLSSAETRKQLLGSPNAEGIHQLLAHS- +> +-KHLDERDILLGLKAASKREVFEAIGQHMQALHISAESVASALHRREAAGSTALGCGVAIPHARV---NELERIRLLYLRLAPALVFDSPDGEPVSDIVALMVPAQEHLDVLAHVASLFSEKAFRKALHTCEEPGQVMEVIANW- +> +-ELLATEHILLDLDVSRKEQVFEAAEQLFGGRHLSRNQVLYALTAREALGSTGLGAGVAVPHARI---RGLAQAVLAYLRPRTPLPFDAPDAAPVSDIIVILIPEDQHLKLLAEVAEMFQDRRFRERLSLCGDADAARRIFTNW- +> +-QLITPNNISLDIEVSSREELFIFIAQQFEKNHISANSVIACLEEREALGSTALGNGIAIPHGRV---KFLEQAHIGFVRLKESINFHATDKQPVKALVIMLVPEQAHLDILAKIAQTISNNKNKNILLTEPSADNIYQLLTAW- +> +-ELLNTQDILLGVEATNKPGLFELVGQHMEQTYLPRSCVTTSLLRREQAGSTGIGEGVAVPHARL---SELDSIHVLYLRPKEFIAFNTPDRKPVSDIIVLLVPAPLHLDLLAEIAHMFSDNKFREELDRCKNEQEIKNLFDCR- +> +-HVFSEDIIDISKSELTRDEAIDTLLSKLNEHHYISETVKDAILKREAESTTAIGMNVAIPHAKS---NAVKQPVVAVMSNRKGIQWESLDGSLPQLVFLIAVPNDTHLRLLQRLSKSLMHDDTRDRLVHAQDKSEIYNILKGI- +> +-TVFHKSLIELTNSEMKRDDVIDRLITELKNQNYVEAQVKSSVLKRESESTTAIGMNVAIPHAKS---DAVKQPVVAVLQNKNGIEWESLDGSLPKIVFLIVVPNDTHLKLLQRLSKTLMDDETREKLITAEDKETIYDILKAI- +> +-HLVHPETTMIHEAPMTRDKAIDYMVENLEKQGYVTTQLKEALYAREAESTTALGMKIAMPHAKT---SGVQQPVVSVLKNNAGVTWKSLDGTVPEVIFMITVPEDTHLKTLQLLSRHLMDDAKREALLNSTSEAELYQHVEDM- +> +-QMIHKNTTMIKTQPMTRDEAIEHMVSNLDKHGYVKATLTRDIFAREAESTTALGMNIAMPHAKS---AGIKEPVVSVLKNNAGVTWESLDGTVPQIVFLITVPEDMHLKTLQNLSRHLMDDAKREALLQSETENVLYQHMIEI- +> +-EILHPEAVKAFGKLTSKKRLFLDLGEVAGACGLEVNSAVNALQDRESLGPTGVGHGVALPHARI---EGLDRVVGAFFRLDTPLDFDAVDRQPVDLIFALFAPAVDHLKALALVSRTMRDPDTCTKLRSNADATTLHAILTAG- +> +-DLLEPGAVALRASAPGKRQALSMVADVAGRVGVDPEAALDGLIEREAAGSTGVGEGVAIPHARL---DGLDRVRAVVVRLDAPVAFDALDDKPVDLLVALFAPRAQHLRALARVARMMRQPEVRASVRQARSADAIHVLLTDE- +> +-NIFLPSDVFVDAPSQTKAKTLHLAATKAS--AVDAASLLGVLEKRELLGSTGIGKGIAVPHAAL---PELGPPRGFIFQLSRPLDFDAIDEAPIDLIFLLVFGESEYLKVLATIARKAHDTMVLSAMRRAENPADL---YAAF- +> +-NDLSINTILPVLKANNQKQALHIMTGYAAR-RMDQRKLLELISAERDSVSPGIGDGVAIHHLVL---QNIREPYILFARAPQPIDYNAVDHKPVDLISLIISPEAYNLQRLALVSRMLRDRVLCECLRGADSADAMSALLHEF- +> +-ALLCEGCVLARLQVADSRGLMARLAEPLSRSGFAAPLIAERLIERERVGTTALGGGTAIPHARL---PGLRARTTVFATLARPLDMAALDGEPVDAVFGLISPEADHLKALAAISRFFRDKDLLRRLRGADSNDALLALLCHA- +> +-DILTPERVSVEAEVRSKPEAVRRLAGLLAH-IFTADDVERVLAERERIQSTGIGSGVAMPHGRI---GSLDRFIGAVLICPSPIPFDAIDGAPVSIHFAIVGPPVEHLKWLARVSKLLRDESFRARLLAARTGRNAFELIAAE- +> +-TLLPAIAGGTDTGVGDKASILAHLAALFARVALDQDLVLKRVVEREELGSTGFGRQVAIPHARL---PGLVRPVAAIIRLDSPVDFGSADGMPVDIVFGLLSPDATHLHALAAISRMMRDERMHAALVSASGPDVIYSLLSDV- +> +-SL-DFDLVLPSLIAVNQKQLLRSLAQEIS--GIGERILNDRLVEKEKESPSAMGEGLSILHLHI---SGLKQPFSMFARLKNGIPMSAPDNKDVDLVCVLLTPEAAYLRTMARISRLLRDAQICVRLRSTQDEKAIRAILEAP- +> +-GLLYPDTVLTDLRASNAKQVFKVLAEYTAQ-SLCVTDVEEQLLEQEAQSPSGIGEGVAIVQMSL---PELERPFVMYARMPNRIDIQAIDNEPVDLLVFLASPEPLHLRRLSQISRMLRDRDFCHCLRSAETEDAVRAIWSTA- +> +-KILKPDAVRVIGAASSKKRLFQEIAEVGHLAGLNPQPTVEALLDRESLGPTGVGHGVALPHARL---DGLSEVCGVFVTLEKPLDFAAVDRQPVDIAFALFAPEVEHLKALALVSRTLREQNFCTKLRANNDPATLFTILTEN- +> +-TNLTSESVFFDPKIESKDAALLFISECAAREGLDSTIIADALIERERLGPTGFGGGTAIPHCRS---DKITRPCGIFLSLAKAIDYDAVDDLPVDLIFCLISPAGAHLRALAEISRMFRNDNNLARLRGAANKDALYAMLNVA- +> +-AFPPPGRILCGLRVAGKAALLEDFAHPAS--GRESAPIRMVPEKRERLGSAGIRAGIVLPHARR---EDLERLFGLLAHLRDPIEFEAIDEPPVDLVALLPLPADDSANGLACIVRRLRDPAVPSAQLAARDAPGLHVAPSRD- +> +-DLLSEDSVLIDVRSSNKRSLLQDLAANAAARGLKSEDVAHNLLKREELGSTGLGGGIAVPHARL---DALERPYGVLAKLKQPIEFDAIDGQAVDIVFVLLLPSNKQLGPLALVARTLRSADTVGKMRKSKTQAELFAAVTVS- +> +-NILTSDRTKAQIHENSKKRVIEKLASIVAS-DIDADDLFHHLICREKLGTTGIGGGIAIPHCRF---ATNGKTYGACMTLERPVEFNSIDDKPVDIVFAIIVPEKSHLETLACLAEFLQQPAYVNKLRSATNDIELFNAATIS- +> +-DCVAPEHVELNVDVRSKPRLLETLARKAATAGVDERAVLLALESREQLGSTGIGAGIALPHASL---VALQRPFALILRLRQPIEFDSIDGAAVDIVCLVLTPAAPHLTLLSRVARLLRAPDALAKIRAAATAKQIHDVLRGI- +> +-DILTSSDVIVIDDAVSKKRLLQEMSRKLAEDGIDERTMFDIVAERENLGSTGFGGGTALPHGRI---PGLRHVKGVFAKLNKGIDFAACDNRPVDLVFMLVSPEADHLSALAQISKIIKDEERCEKIREAATGNDIYRLLTSD- +> +-DVLSKKTVVVELKGHDKNAIMAELTDCLADEKVLSDAFLKAIKEREALESTAIGGGIAIPHAKH---ESVKRIFCAMGIIKDGVEFNALDGKPVTAVLMVASHPREYIQVVARAARLLKSEVMMQKIYAASSSPEIMKVIADF- +> +-DGMSVERI-VDLKATSKDEAIAELIDLAVTASAVDEQLLGRVLEREALTSTAVDRGVAIPHARS---EQVKGVVVSLGIHRSGLDFGSPNGDPVHLVFLVLSAPPAYLSILGRTARIFRSEQMLQSVLGATGAEQIVKIIAAH- +> +-DYIAEDTIALELRGEDKKSIIEKMAQILTDAKKINDVFIEGIQKREEIESTAIGNGIAIPHTRG---DFCDRIAVCLGRINKGVNFNALDGKPVYIIFMIAAPTKEYLQLIAKVARFLRAENNRKRILMAGNKEEIIQVIKDF- +> +-NFLKKERVIMNLKNDLKEKILEELIEYIPVGKISNAKIFDEVMKRESLESTGIGNGIAIPHAKF---NTLGGFYIVVGISKKGVDFAAIDGKPVHIIFLVVSDTILYIRILARIARLLHNKSFNEKLLKQTTENDVINFIKKY- +> +-DLILPQHVA-WLETRSKSEALSQLLQRLSQSRAVKAALRNAVLAREVLMSTGIGYGVAVPHAKI---PTVESFVVAIGISPDGIDYTAIDDAPVRLVVMIAGPDEGYLTLLSTLMRFIKSE--KGKILSSTTPEDVARLGRRY- +> +-DVLAKEHIIINLYGMNKFEVLEKMVKVTKSSAKVVVDLLEKVITREKIKSTGIGGGIGIPHAQT---LGVTDFIACLGISQDGIDFNALDEKPVHLVFLIATKENIYLELLSSIARLFVDETFKQKIIKSKSPDEIMQLISEK- +> +-EMLDESRII-DLKASTKDEALRELVNVLATSPDVTDDLMEAILERERVISTGVGIEVALPHVKI---ASVKDFVIAIGRSTRGIDFESLDEKPVYIIVMIGANDGEFLKVLAQLVLKLKNKNFRKGVMFAKDAARIKQMFVRP- +> +-ELIERAPLV-ELTAKTKEEALRQLAEAFRGEPKVADRFIEAIFAREKVISTGIGIGVAVPHVKI---PEVSDFVLAFGRHREGLDFDSLDDQPVHLLAMIGASEGEFLKMLARLVRTFRARDVRRKLMQAENAEAFRAVLREN- +> +-EYIARERIA-FIEAENKQDALAKLIALSEDDRLVINQFQNAVLDREYIVTTGIGQNVAIPHIKS---RWVRDFFISIGVFRNGVEWQSLDEKPVHLAFLIAGPEERYLRILAKLTLIIRDKEKRKAIIGASSPDEVYRLLENS- +> +-RLLSPERIV-WLSSCDRGEVLSELARLHTSFDTTIEEVRRALVEREQLNSTGIGQGLALPHARI---PKVQDFSVILGLHKGGIDFNSFDGEPVHLFLLIIGPTDRYIQILARASRFLRAK--AADILAAATADEIYAMTLDF- +> +-RLISPDRIT-WLDQDNKIDCLRGLVQCLSKSEELGDSIFDAIMEREQLLSTGFGLGLAIPHAKL---NIIDDFIVGLAIHREGVPFDSLDDQPVHILVMILGPDDEYLKVLSRVTAFLKDQ--RESILSLEDNEELYKLTFDY- +> +-DCLSIDRII-DLECDRKAEVMECLIDVTSTASVVHEDFRQAILRREEILSTGIGLGLAVPHAKI---GTVSSLVMSLGRHLKGIDFDSLDGNPVNFVVMIGANKQGYLNILAEISGFFKDVTFRDRIMRARGPEEIMALFS--- +> +-SFIEQQQILVGLKVNSKKHLIEALCAEAAKAHIESRDLCAAVMKRERLGSTGVGNGVAIPHAAI---NSVDEPIAVMAILDSPVAFDAADGRDVDIACLVIGPEQAQLQMLSSVSQVLRKATNCSKLRAAQTAAEALMAIQNI- +> +-EFCFENNLMLGVPAKDKRSVVQIIASHLALRTMPFNVIFDGLMDREALGSTGFGDGFALPHALI---SDLSTPARVLVTLREPIDFDAADDEAVDIFVAVIWPQDGFLQHLAKLCRLFRSKKLLVALRSARSETEASILISAH- +> +-DTLGAGDVLLIDALSVKEELLGLIGAHFAGVTLERDDIAEALAKRESLGTTGLGDGIAVPHAPI---AGLDTACLTFVRLGSPLAFDAVDGAGVDLVCAILFPDPAGLKLLACVARTLRRPDVAKELRKATTADEIITALAIE- +> +-NLLNSNSYLMIDNPTSKKMVFXTMCIKAXETFIDXNQVLNDLXKREKIGTTTIGNGIXIPHVQN---NFVTKPVSIVTILSKGLDFDAIDKVPVDIXVFLILPESENXQILAQVSRXLRNSDIINKLRGSKSEDSAFAIISQF- +> +-EFLKSKHVIFDLHVNNKKHLFQELSFKSSLIKIDDKELFNGIINREKLGNTYIGNGAAIPSAML---ENLSNTFILFSVLTKPIDYNLDDQKKVDIICLVVSPKSKHLYFLSNFSRILKHDEITKRIRGCDNPDSLKAVIMNF- +> +-EFIYKNSIFIDVTADSQKNVFKILGNIFSKKNNLSSLIIDKLNERERLGSTSVGNGIAIPHTKV---NGIKETQVIFLKLRNGVDFSASDGKKIDLVFSIIAPESDHLLILSSISSFIRKKQKVDRLRGSTTIDEILFLFSKI- +> +-NFIVRDAIIPSLAAPVKETVIREMVGALHAAGHFRDEIVRAVLRREDLGTTGIGRHIAIPHSRH---PAADRLIGTLALSRDGLPFDSLDGEPVYVFILLVSPQGDHLRALEAVVRTMRNDDFVRQLRACQTREEIWALLESA- +> +-DIVVPDAVRARIRATTRDEAITELVAALVEAGAIAPEIIKAVIKREGQATTGIGKGIALPHAKL---KGIKKPIATIGGAPDGIDFSSLDSKPVYSVILLLSSPDEHLQAMETIFHHVQRDLFRKFLRQAQTNEAIVDLIHEA- +> +-DLFSIEQIVLDSSATTKDEAFQELATIAYKAGCIDDKLTKALWAREHETSTGLEDGFAIPHARI---KYIKKPAVIFVRYQTGLSWPTFDNSAVQVAIALIIPTDIHLEVLSNVAKKLLNPDLRQTLKKENDKTKILALLQAE- +> +-DKLSKKQIILDLDVKSKEEAFTQVSIIAKKLGFIKKILEKLFLERELEISTGLEEGFSIPHAKG---PQILKSGIFFVKYKNNLEWETFDNKGVKFSIFLLISESNHLKVLSQISMKLVDKEYRQKLSTTNNVDEIIKLLEHT- +> +-ALTSNDLIILDQDYSSKREVFQAVADRLKQKGTISSNFIDSLYAREKDGPTGMDKGVAIPHAKS---SQIKEPVFSIVRTKKPIDWESIQPNKVSLIFLLAIPKDFQVKLLAKLSRAMLDDQFISTVMKASSTGQVMAELGRV- +> +-HATSENLIFLDCSFTTKEEIFDFVAKQFEKENKVSQEFKKALFERESIGITGFENGLAIPHGKS---STVKEASFAVVRLQKSLEYASLDPSKVDTLFILAIPETTHLTLLADLAGRLGDINYLNQVKSAHNAKEMIKVLKQK- +> +-SLTHPSLINLQTTFTSRDEAIRALAEQLDQQGKLHQQYLDAVFAREEQGPTALGEGLAVPHGKT---DAVKEASFAVATLKQD-KWKGLDEDDVNLIFLIAIPNSTHMHLLTELTTTLVDDDVREAVLNATTTDELLALFNKP- +> +-TIVKREMIFDNIKSRDKREAIRIISHLCSRHNAAYLRLIDAFRKRELLDSTGFGGGIAMPHARI---RGLCDPVFAVVRFAWPVEWEAIDGEPVDLAVVAITPANKHLPTLAMLARKLMNDEFVYNLKHCTDKNQLYDYMLR-- +> +-DLLKPENIHFDVNGHSKKSALKAISKLCGHYSTIKSALYKNFVGREKIESTGFGGGIAIPHAKI---DNLTNPFIAIVRFSKPVDWDSIDGKSVQVAIALVMPTNTHLEVLSHFSRKLADDEFLNRLLTEPDAVALYNYIIE-- +> +-ILVKKEKIFDNIVSGTKKEAIRTISRLCAKQTMLDTQLEEAFWKREEWDSTGCGEGIAIPHAII---KEIDEVQLFIVRFRYPIEWESFDDKKVDIAFAIIAPEEKYLVFLSRLARKLVDEKFIANFRNCRSTEAVYQYVKN-- +> +-DITEEHLMDL-NLKSTKTEAFKEMLAFKGIDQFINETVLEALEAREAESTTGVGQQLAIPHAKS---AAIDQVKVLYGYSEKGIDWDSMDGQPANMVFMILVPENTHLKILQMLSRKLMNDDFRTAVMNAKTKEELYQLFKE-- +> +-EYLRPEHIVLDLEARDSAEVIQTLVRRIPELEAVDAAVAEALLAREAAHTTALDNGVAVPHATV---AGLDRPLLVVGVSRDGVRYGPAGLEPVQVFFLLLSPPALHIKLLARIARLVRRPGLVERLGGAASPEAVFRELERV- +> +---YLTPLYLKDVSAVSRLDVIRELSALAAQEGLDSATIERKAWERELIAATGIGHSVAIPHARL---KDLKEPIVAVGTSEAGIPFDAPDGLPAHIVFLLITPQEAQLELSADIAHTFREPRCQEQILRASTYTELVAALKT-- +> +---LIQPHI---IPSLAAGTRRDALAEMVRLVGFDQGPLLTALQEREAIGSSAIDPGLAVPHARV---AGSGELEVCFARSAAGIPWGAPDRQSVHLIFLMVASRDNYLETLANLCRFLRDSSNRTLLMKASAEE-LVSFLTT-- +> +-TYITLEAVRLDLNLSSLKRLFEEAGLALESAYIPHDEAFTALNERERLGSTALGFGCAVPHARL---TGLEEPAVVLLRTLEPLKVPSPDKTGAQLFIVILAPEDDHLELLRETAELFSDAEARETLLKASTPVEVCEFLTH-- +> +-SLLKPDNVLLGISPSSKKRIFEQASQTLSLLYLDKKEIFDGLFARERLGSTYLDHGIALPHCRL---PNIKEPCCLFVKLHGELESDRPGEPSVSAFFFLIAPESEHLALLASAAEVFSDDALREKLLTASSADAFCGALRS-- +> +-TLLSTDRIIFTDEVSSMKKAFEQLSRLLCRNSVCADEAFDVLISREKLGSTALGNGIAIPHACM---P-IPEPVAALLVTGEGIKMDSPDKKPVHTLLALLIPSKSYRPLLKAMAANINQKDLSRILLEQQHPGVALEYISS-- +> +-ELLPPANVLVDVEVNSVKKLFELMGVFFENRYLSKDVVYQALFARERLGSTMLASGWAMPHAVI---TSISEVLCGLVLLRNSIVFDQRGWRASVFLFVLIPPSDRVSCVYNEWRLLSEQKDVVETVEGMDNPSALYQYLFH-- +> +MEINKPEFVFINLKQKNRDDILKELATRAVKLNLATDELYQAFLAREKESSTALPDLFGIPHART---ATVKQPALLFAKLHQAVEWDEEKK-QVQYLFVILVPQNTHLEIISNVAKLIMDKNANQKLISSNNPDEISKLIVSY- +> +MKIFTIENIFLNQKLDSKQQVFDFVAQVAVEKGIVNKQLVVDLWSREEQITTGIEQEFAIPHCQS---NVVSKPTLFFISLQTGIDWQNFDGTLAKYLFVILLPKTTQVETLSKIATLVLDSKISSILK-SNDKNAIFEAITSQ- +> +SDLIHPELICLDLNSTTKHAVFNEMAEYLFRAGKIHHAFVQEVLKREATGNTGFEGGVALPHAKC---ASVLSPAVMIGISREGIDYGAEDDKPTHLLLMIASPEEAHIEILAQLSARLVDDDSVSRILACRSEQEVIDYFCRP- +> +SQFLSSELVKINLQSKDKKSAIKELSGLFETKQIIKNQYIADVLKREEEVSTELDNGVAIPHAKS---AAVIKPAVAIGISRNGIDFSGE-GRLSYVIFLIAIPQDTHISILSNLTSHLLETDCIQKIKGAKTEQEVVDIFSKE- +> +NKIFSKDLIQLNIKSSTKNECIEELASLLYKQGKITKKYLQDVHKREEEFSTELENGAAIPHAKS---IHVKSPAVAIGISKKGIAFGSDETKKTHLIFLIAMPENTHIHTLSTITSKLLDENYVTKMINSKSIDDLIYLLENN- +> +HALFSEKLVKLSLTGLTKDQIINEMVEVLWKDGRLSEQFTKDVYAREAEITTDLEIGAAMPHAKS---KAVCQPSVAIGISQKGVIFGES-KEKSYVFFMVAMPEKEHIEVLGKVTGVLLEKENITALKNARTEEDVLQLFCQE- +> +LDFLKRELIFISDEIKSKEDAINFLVDKVGEKGYTDNGFLQGILDRENIGDTSWENGVAIPHFIG---DVVKTSFVSLYIKGDGIDWSDD-NPPVNLIFLICMSKNEHIKSIAFIAKLFENDDFKNILKTVNNPDEIYAYVENV- +> +-NLIDKDHIQTQISISSKKALFAHMSEHICQLHLADEELIYALAQRERLGSTCIGEGIAIPHCRL---PHNGKCILSLYTLAEPLSYND-DNETVDIVALLLVPEDTHIELLSQLAHLLFKPELRSELKSAKSNTDAFRAL---- +> +-EMFTRDNVLVDVPADSQEDALARIAAMATDRGYAAEGVLAGLQAREAQMTTALMDGIAIPHAKH---PAITEAALLVVRFSEPVAWPT-DKALVSVAVTMLVPETTHLKLLAKVSRALMDEDLRATLTSG-TADEIYTPLSAK- +> +-DILNTDQVEFDLSATNRNDALHQLAQLAVAKGIATEAVYQKYLNREKESSTGMEQGIAIPHAQD---ASIERSAMLVVRLTKPVDWPSFDNQPIDTMISFLIPEGAHLHYLSNTAKLLTHQSFIKDLKAAKTPVDVVQLFRNP- +> +-DVIRNDLIFTDVQVSSQEECFEQLADIAVRSGLATKAVVSGFEAREKESTTGMEHGIAIPHTEL---AEIAKPALIIMKLADGVEWNSLDDSETRLVLAMLIPKHGHLAILSEISKLLVHESFINELMQAKTKNEIEQLFKEK- +> +-TLLDKGNIYFEKGIQTKDELFRFIAEKMQDKGIVSERLVEAFRKREEQSSTGMENGFAIPHAQS---ETIKKAAMLAVKLEEPIDWQTFDKKPVTFVIAFLIPPEAHLHYLSDTAQKLVDQRVVTALNTATDADQVYALLH--- +> +-DVLQKENISLAVQGSNKDEVLQNIAAIAKEKGIISAATYHGFLKREQQGSTGMEQGIAIPHTEN---NAVIRPALMVVTLARSVDWDSLDGQPTTHVLAMFIPTSNHLNVLSDVAKLLVHDDFITELKTATDTTTIYNLFQNK- +> +-NLVDSKRVFLNKSFNNKESALEFIAQQSVETNVSDNSVFEGLKARESESSTGMENGIAIPHVSD---KSISNASLIVIKMDNKIEWPSLDGKPTNFLISILVPEEAHLNILANLSRKLMDKEFTNQLISSNSKEEIVNLLSGV- +> +-ELFNQNTSFFKQEFKTKTQIIDFLASKLKEEKIISTVFLNAIKTRENQESTAIGNNVAIPHALN---SVVLKPTICFMSLKTPIKWNSNDNQLVDLIFMIATNDNDHMDAIAGLSSKLLDDNVLEQLKQIDNFDQLIELFSDD- +> +-DLFNQNTSFFKQEFKTKTQIIDFLVSKLLEQKIISTVVLNAIKTREKLESTAIGDGIAIPHALN---EAVLKPTVCFMSLKNPIKWNNNDNQLVDLVFLIVTNDDDHITAIAGLSSKFLDSNVLNKLREIENFDELVEIFNDK- +> +-NLFHRKNICLDEASQSKTAVLLKISQLIHQNNLSIESLFDAFWKRETLGSTAIGHGIIIPHIRS---QAAEETQACFLKLKTPIDFGAEDKQPIDLVIGLVVPQTQHLALLNGICQEFGKPSLRNACRAANDEEELFRLLVK-- +> +-QVIHPGCVCVDSSSQSKTAVLLKISQVLSQVYLDAQELFDAYWKRESLGSTAIGQGITIPHIRS---TTIEAPKACVIRLLNPIDFGAEDKQPVDLVIGLIVPQNQHLQLLDAIIKQFNQTSFRELCRQTTCSENLYKLINS-- +> +-ELLREENVILDREAKTKEEVIRILTKHILTENGVTTEIVKAVAQREKLAFTGIGKRTALVHAVT---AGVKETKAVFLRTVSPVDWAKGKDYPERIALLLLIPEGEDVEKVKQLVLKLGKKENARRLLEVSTKQEVLKILNGE- +> +-ELFSATDVILDAAPGTKAALLDRLAAEAAVRGRSAPEILEALLAREKIGSTALGRGVALPHTEL---AGLAAPVVLFARLQRAIDFDARDDEPVDLVFLALWPAKGLLAAMAEICGGLRDPQSLRRLRGAKTPEDAAQIILQ-- +> +-TILGDEDLLLDQPIDSKAAVLAAAAEHLGRSGVPSEVILKALSDREALGSTAIKHGVAVPHAGL---DNLPRPAAVFFRLAHPIEFDAPDDNPVDLVFVTVWPSSGLLSALGHLCRNLREPSVRQALRTASTPQEIKSALSR-- +> +-ELFSAADVILDAAPADKPALLDRLAAEAATRGRPAPEILGALLAREKIGSTALGKGVAFPHTEL---ADLAEPVVLFARLQRAVDFDARDDEPVDLVFLALWPAKGLLTAMSEICGALRDPQSVRRLRGAQTPEDAARLLLQ-- +> +-DLCPVQQIVLDAPLTDRNALLTYCANLAAPAGVRASVLLQQLQDRERIGPTSLGRGVAIPHARI---AGLAAPYLLFVRTLQAIDCDAPDGKAVQDFFVLLMPAQLHLQVLADLVSALHDRYFRQALHAATSAPAINLLLSS-- +> +-LDIIPEEIVINLPGGDRASALHHLATVLSRERVPTQTISSALLGRERMGSTAIGGGVAVPHALL---TDIAEPAKCLAILKHPIWFDAPDSEPVSVLLALLWPTNSYLPSLAGLMRRLRDPKLREALAAAQSVEEAALALSV-- +> +-SVSFEIDFTIDRTSRSRKAALGSLAQRISCRDISPHDISNCLLAREKLGSTAIGSGVAAPHTIF---KQSCTPLVQVTQLKYAIDFDASDATPVDVLLSVVGNRRWLHLALPRFAKLAEAPELAARLRAAKSASAVEDILAS-- +> +-SVLDPSLFVPDLRTRRKESVLGEMIARALAGVRLPELLRETLVLRERAGSTAVGKGVAVPHARS---LSVSEPHLVVARSRRGLAWTPGDPQPVTLVLLALSPAEGHLDFVARVVGATRLQRNRQKLLEAESFDAVAAVLRE-- +> +-EWLTPGAVRFGLHADDVSTALAAIADHLEPRALHRRELLQRLLDRERMESTALDNQTALPHCKM---AGLPAPVVCIDRSEDGVPFRPGSDERTHLFFTIVSPEATHLKVLAAVARFLRDAQNVRAVLAATSPSEVLEYIQR-- +> +-KLVRPELMNFDVVPGDKMKILGQLTFPMIQSKFLTKYFLDRLIERENMMTTGLGNGVAVPHPRQPIPNLFPESAIAIGICKEGTDFDADDGKTVYAFLTVCSSDVHHLRILARIAKFASDKSATKKLIKARIPEEIIDILKES- +> +-RLIKKDLIVMDIKPGTKNEVLEQLARPVLRNGTVYSGFLEKLMHRERMATTAIGKGVAIPHMRNPRENPVSGPALVIGICKAGTDFEALDKKKTYLFFFICTDSVIHLRVMGKLAGLMRDEITVSRLIESNGRDVVLKIILEK- +> +-ELITPDCVRVQKSVVDKRHVLEDLTTLAIRSGRLTTALLRSIEERESMFSTAMDEGIAFPHPRRPLEGL-QEPLLAILIVEQGVIFGAPCGGKTYVFVLFCAPDSAHVRMLARLARIFYQKKLISKLRRMQNPELIIQELINV- +> +-RLIHRDLITLEIKPGIKEEVLSQLVEPFVKNGIIPAEFFRRLVSREHMASTAIGKGVAIPHIRHPEENPAGGPLLGIGVCREGTDFDSFDGQKTYLFFLLYTDSLVHLRVMGKLAALLHDEKTVSRLITAQKEEDIIKIILHS- +> +-RLIRRERILTGLPAGSKEEMLDALIAPLSLSR--EKLFLKKLMQREDMSSTAIGQSIAIPHLRRPEENIITGPEVILGICPEGCDFDSIDSKPTYLFFLIITDSVVHLRIISRISQIAGDRKLIRKLVNATDGERALGLILDS- +> +-RLLTEDRILLDLQATTVEGIIEELTPPMLFSNLVFNDLREKCLAREQIVSTAVGNGLAVPHPRDPITTLRAPGCVIIGRSVKGVDFGAADKKKVHLFFFQCSQSELHLHLMGRVATLLRDEAFVKICRNAKTPEDIIASVMEH- +> +-RLIDPGSIIMNMRSRDRDGVLRELADLAQARELVKDTLFSKLVQREQMLSTGIARGIAIPHIRRPGETDIQEPAIVFGRSPEGIDFASLDGTKTHFFFLLLSDSTVHIRIMSRLAAMLRRDDAREQLRRAEQPQDILRFFVEY- +> +-RLTDESCINMDMKSRKPDGILYELAEIAQESGIAVENLLIQLKKREQMLSTAIGKGVAIPPPRNPSDELFRKTGLIIGRSAKGLDFDAPDGKKVHLFFMTCATDVLHLNLLSKIARLLDADGFIKRMIRVKSKKDIMKLLLES- +> +-RLTDESLIVTGIRPGSAEQILNALAAPLAEQGIIRHKFVDSLLQREQMMSTGIGGGAAIPHIRHPEELPAARPALVIGTCPEGIDWKAIDDRPVKLFLLPVSADVSHLRLLSLIRKVLLDEELSSRLIQAAAPHELISLLLKY- +> +-RLVDTGSIIMNLKPGTRREVLAQLIRPLEAMEKITAAYLDILLAREEMMTTAIGP-IAFPHARNPRENEGAEPQVIVGICREGTQFGSLDGSPTYLFMLPFTDSIIHLRLMAKMAVLFKEEKNVRRVLEAKSGEHVVGVLISL- +> +-RLMYPGKVLLDMTPADKPGIFRQLVQPLVQDRIIGEPFIIRLQERENMVSTAVGRGIALPHPRHPGDVHATRSSVVFGRCPQGVDFDAPDGRPVTLFFLICATGVVHLRIMSRLAWMLRDVAFVEQLGSVVSEADVLTAIMRK- +> +-RLIDEKSIITDLKGQTTKEVIHELAEKAYINEFVANIFIKQLLEREQLTSTSIGQGIALPHLRKPNGNIVTEPKIVIGVSKEGIDFDSLDGEKTTLFLLLLSDSVVHLKLLSKITRIFGIDNAISQIKQLRKPEEFVKFFNKI- +> +-EILRPELMSLGLRPGPKPVILRQLVAPLVEAGFARSRLLAGLMEREEMMTTGIGNGVAVPHLRRPVPGMFSTPAVAVGTCPQGTDFAAIDGQPVHTFFLICATRDIHLELMARVSWLSRQGI-AEELKDARSAQEAATIILQA- +> +-RLLPVELVGLDIRPGAKKQVLEQLLDVLAGGGLPVRVFLQKLLDREDMVSTAIFPGIALPHFRKPEECPLPEPRIVLGICRQGTDFDSLDGRPTHVFFLICAGNVVHLKIIAELALLFRRGSLVEELLAAPDPASALQVLFR-- +> +-SLFSTDAIVADLAADNIDGAFDELLAVLGKSKKLGKQARAAFTLKLEQGATGVGHSVAVPHVKI---PGARSTVVALGRSERGIDFRAGDGTLVNLCFLVITAEGEHLDFLRWIASLARDPDFPRFARGCQSSAALYDLLEEM- +> +-GLLDHRIGIDELSTDDVASTFSAIVDALVSGGAIDDTLRDALIARESSGSTAFQYGFALPHVFS---DLVDRIWVAAARHPGGLDMAAADGEKTTIIICIVGPEDAYLSLLRTIAGIVRDGHWRRFMHQALTASDIFETLLEA- +> +-DFLSADAVILDLDAADRDQVLGALADALVQRDPELDDIYNGLVEREAQGSTGQ-QGVGIPHIKL---SGISKVSMVVGIHKEGLDYDALDGEPVHVFFSVIRPEEDHLDVLRWIAGIAGHQDFVSFARQASETGQVIDLLTEL- +> +-ETLAPERCQLGLQASSRKKALQVLANIFSQSSLDSFEILQALTEREQVGTTAIGNGIALPHGRL---SNCEKPIAILATLDTPVDFFASDKENIDVMFALLIPKFRDLAGIEQVKTIFDNKTFCAQIRNAHNNEALFDIIEQ-- +> +-DLMAAVRTVV-SPAADRNAVLHTAAELLSCRQAGSAELYANLCEREALGSTAIGHGIAIPHGRC---PNLTEPRGALLRLNTPVAFGRD-E-PVDLIFAMAVPAHQHLMLLSELAERFSDAAFRQQLRAAPNADALMALLTD-- +> +-DLMAAVSTRV-LAAADRDSALRAAAGMLACREAAEDALFHSLRERESVGSTAIGHGIAIPHGRS---STLQRPRGVLLRLQRPVDFGG-SE-PVDLVFAMAVPEHQHLMLLSELAEIFSDAHVRDALRAAADGDALKRILDH-- +> +-RYLRPESVRLELNTQLTESVFGEIVELLSATGQVCRKLLTDLLNREKKAGMALEGGVAIPHVRT---MQARSFVIALARSTPGLPFGAPDGDVSRIFVGLVAPPRLYLRIYRTLAPLLMDPDWKNELLAARDVHEVLRLCEGV- +> +-RFLQPELIKLELDATNKEKIIEELAVLLDKSGKVRKRLTRDLILREKKVSTGLGHGIAIPHVRT---IQVSEFVIGFARSGPGVNFDSIDSQQTHLFFPMAAPPSLYLRVFKSLAEVLRYESFRQMLLEAKDEYEAMRAFREI- +> +-QVLKEETVNLNITQGMKENVIRQIVELVEHSGLVGKKLLLDFVNREKRCTTAIGSGIAIPHIRT---MQVRGFVFAIGISKDGVYFASMDGAPTHIFFILASPPTDYLQIYRRISELVQNQNIFFELTTAGTPGELIRIVKDF- +> +-RFLSEDLIDLNFQVDNKEHILAALVKLIGNSGRTGTKLLTDFINRERKATTGIGNGIAIPHIRS---MQAKEFILGFARNADGYDFDSLDKQPTHMFFIMAAPPNLYLRVFKALAESLQYESFREELMQAEKPFDIIRAFRSV- +> +-KYLKESSILLDYQLDVREVIFKQISTCLETVGKINTKLYNEFLEREKKDSCCIGDHIALPHLRT---LQCKELLISVITSKQGIKFNAFDDEPVKIFFSFVAPRNLYKTLYKNISRIFQDPYTIDTLLSFEQPGELIRYLKKE- +> +-PIVTSQIVSLDVALDDSTQIVRALTGLLADAGRVDDVFVEAVLAREALGPTVLPGGIALPHARS---VVVTAPSVAVARLPEPAAFRADTD-PVRLVLLIAGLGAGYLQVLSKIATACVKYSFVDELLRVRTAEDMADLVGQ-- +> +-ELLNPKSIFINIDVNDHNDALEMIAKKLYEANFIETRFLNALNYRENLMSTALNDGIAIPHGIS---STVIQPTISLAILKNGIDWKAEDNKKVNLIFTIVLSKEIQLDSIQVIADYSLDDNFHSEIMNAKTQEQAYEILVK-- +> +-NFLNKNSIFVHSNFDKKDDVLHFLSHQLNEQNFVSKKIYEAFLYREELMNTAIGGGIAICQALS---STVKKDTLCILTMNNVNDWKADDEKNVNLVFALVLSKNLQIDTLQMISILALDNTLDNKIMKAKNADEIYEVMSK-- +> +-KMLDAETINLHSDSINKYDAIKEMANMLYKSKRINTKFIEDVFKREKLESTNMDMGVAVPHSNS---IFVDKTSIAIVRFKKEIDWEDGG-EPVRCIFLFAVSKGIHLDIIAKIAEILIDDDFIDFLNKTDNSKELINKIND-- +> +--FVLKAHIRFQFDAQDKTDFFKKMVKDISVFHEDFERLLELFYLREETMSTGIGNGIAIPHVMY---EKCESQEIFVYRLAKPIDFAALDKKPVELIFVMVGASIINLQILAKLALMMKHPEFLDKLLSAESEDALFEVLIH-- +> +--LTSKNLILLDAVFEDRLEAINVLTDKLEQSGKLTQMFLDAVLKREEEGPTALGEYLAVPHGKS---EAVTEPVFACALIKGELMWQGLDGEPVNMIFLLAIPPSTHMELLTTLTSSLVDDDFREQLLQSRTTDDVITLFGGE- +> +-DYLRSRNVILDFKADNKYEAIAEMSKKAKDLKIVRRWLYQVVVAREELVSTAIGKGVALLHPRHHHPTKIKKPSVIFGRSAQGIEFDAPDNKPVNLFFMLLLHDIQHLFSISYISKFLMNEENLEILRTATTNEEIIHALTR-- +> +-SFINSDFILRDLNAKHRFEVLATMSQFAKENSVCTSWLFDMLSKRERLLSTGIGSGVAFLHPRSVHTDKINFSAVLLGISREGLDFRSLDRAPVNLFFLLLLKTQQHLFALSYLSQLFREDHLKEKILQAPDNKTILELLKL-- +> +--MFQEAFIVLDADYKTQAEFFCASSAILKQREYVKPSFCKAVMEREALYPTGLAIQFAIPHTDA---FHVEKPFVFVTRLKNNIPFMHMGPVQAKVIFMLGIKNEKQVGLLSDIMKCFNDGDFVRTILSIQDTHAMADYLKKQ- +> +--LASPDAVWLGLESDSAHALLSDMSQRLLDAGYVRPGYSESLWRREERYPTGLP-GVAIPHTEP----LVRRGVVAIASLARPVAFEEMGTVPVSVVFLLGLDREGHVDLLQRLIKAIQKKGIVEEIRSADDPEDVAARVNVL- +> +--KIEEDLVLLNIKAKDKVEVISKLANLLRKEGCVKDSYLNAVIKREGIFPTGLPQSIAIPHTDA---EHCLKTSVAVATLEEPVKFGLMGTVDAKAVFLLAVDNEKQVMFLSKLFHIFDDSNSLVKILNAKKPKEIVDELLRA- +> +--MLKPSLVLDDLAGDSREEILRTMAEYLVKEGRCRRTFVEAILARERLYPSGLPPKIAIPHTDT---IHVHRSALLFVRLRTPVEFASMGTFPVQLVSMFALQNDLVGNVLQTLITLYQRRQMLEDLLRSKDAREMYQILVSA- +> +--FFKNDLVFHDVDWVDTADFFHKISENLVRGGYVAPTFYGAITERELNYPTGLQIGAAIPHADP---VHIKEPFIAVIRPTHSIAFAPMGKIQAKIIFVLGVMRGLQVKVLQRLMGMLSDEAVIHQLLQASNEDEILRIIKNS- +> +--LLDKELIVLQSNAQHYSDVFKELGQTMIDKGYANANYIEGLLEREANFPTGIQAGIALPHTDA---SFVKKSKIGLLVLENPVQFGMMGKVQVNIVFLLGCSENQHLLALQKVIELIQDADFVEKILSLESKNEAYELLSSN- +> +--MIPRDFIFHQVNVQNRNEFFEHFSNLLEKKGFVKTGFASALKIREYDYPTGLP-GVAIPHTDG----FVQKDAIIVATFEHPILFHEMGTVEVRVAFLLAVRDKKHLEVLQKLILAVQNTAFIEEMLAADNQIELANIVEKE- +> +--TVLPGAAIVGLEAEDAPTALRALSARLLGIGAVTDSFEAAVLQREEMHPTGLP-PAAIPHTDP----HVITPGFAIAVPKEPVVFGEIGTIWAELIVMLVLADHSQLAALQNLVARLQEPQAVRDMLAATDDADLERRARDW- +> +--LFQKELIFLNEHFEDQADLFQKISERLYSQSYVDSGFLLSLQTREKEYPTGLHFDVAIPHTDP---VHIKRPFIVAVRPDPPLDFQAMGHVDAALIFILGLQRGNQVLLLQKLMDLFLDEQKMKQLLRIADQEEWLKEIQYF- +> +--AEQTGFIGTTLEAKTKEEAISALAGLFLENGFVKDSYPGAVLAREQIFPTGLPFGVAIPHTDS---VHVIRPGIAIGVLKEPIEFGMMGAVQVKLLFMLAIKDNMQIQLLQDLIGLFSVAPLMNQLIVCTESERIVELVQSY- +> +--LLRPEHILLNLDASSAREAIDQTVAALVRTGHAEPAFAEDVWQREQVFPTGLPLATALPHADP---EHVRQTAVAISTLKAPVRFGQMGGLDVHILFLLAIKEEKQVELIQEVVGLLQSPGLLEQLMSAQSPERALQVLHRA- +> +--MIQKDCIFLNLKVADRHELFEQVGEKLKHIGYVKDTYVDALNEREAEFPTGLMLPISLPHVDS---VNVNRAFIAVVKNDKPIHMLQMGDMQCEYFFFLGITDSHQVILLQKFMQLLRDKSFVDRLICINNVDDMFEFMQEN- +> +--TFSNELILTGIKAASDLEAIETAAKHLFEKGLVKESFISAIQEREKVFATGLPFGVAVPHTDV---EHVVEQTICIGILEDPVPFKVMGEVDVKIMFMLALKEHSQLAMLQAVIGMVQKPDILEKLATEKDTGAIYDLVMEE- +> +--MIHQDIIFPEREVKNQGEFFHFVSRDLYEKGYVHPSFEKAITTREKKYPTGLQITIAIPHTDC---EHIIQAFLCVNRIISPITFMQMGKVFPEYVLVLGITQKEQVTLLSEIMELFSQETFVQKLRCATTTSDIYSAFIEG- +> +--IFREDLIWLDETFEDKDQFFDKIGKRLYEKGKVKESFADGLKSREAVYPTGLKYEIAIPHTDV---EHVREASISFVRFKETVLFSHMGQVNAKFAFVLGVKESQQVEVLSTLVLLISNEAEMAKLEVLNSPAQICALLNEF- +> +--MLHSSCVQLDVEAQDWQDAIRKACRPLMGKGFVTEGYDEDVIARELQWATGLPVGVAIPHSLT---PHVITAQIAACRLSQPVKFAQSGKVDVSIIFVLALKDKEQLSLLQKLMTTISNEETLASLMGTSTPLE-------N- +> +--LFRPENVKLNVKCCAAEDVIRQLGWALTENGDVVDGYAAACEEREQLYPTGLQTGVALPHADS---HYVKRSAIAVATLLEPVTFRKMGDVSVRAVFMLAPQKEEQLLFLEGLVAFFQQGDLLQKLFSRSSAHQAAQFLQKY- +> +--LLDDDLIFTEFEAKNKEELIYKLSKIIEEKGYVTRYYANDVVEREKKYPTALPMSVAIPHAES---SNVKIPSIVIAKLKNPISFIEMGEVDVNIVFLLAVKGKTQLKLLPKLISIFSNKEEMRKIEQANHSKQIFQLIKDA- +> +--TVMPQIMGYQITGTERDDVLTEMADFLASMGMVKPTYAKAVIDRENIYPTGICYPVAIPHCER---DGVLKTAILVGQTRNGITFQRIDNVDAKVIFMLAVDTQGQLEVISKLMDVIQDEKVVEEIVHAKTCEMIKEIVTNA- +> +--MLHDELIFMKYPAKEREVLLKELTGILKDRGYVKDSYSEALLTRERKYPTGLNVPLAMPHAEA----HVNKPAILVARLTEPVQFKEMGDVMAKFVFMLAVRDEGHLAMLSKFMSIFSQENQLKELYAIEDKQALREELEKI- +> +--LLNTKFTSINIEATDRDHVLTAMADQLDESGITKPGFLEALLAREKKYPTGLP-GVAIPHTDP----YVTRDALAVTTLRTPVLFGQMGEVPVSVVILMALSNDDHLSMLQNIVKSIQDGDLMKTIRNAAEPEEIVSLVRAM- +> +--IIDLDLIELNYKAENKEEIIGRLSELLQKKGKVKATFKEAVLEREKVFPTGLKITFALPHTDP---EHVNETGIAVAVLENTVKFSSMDILDVNTIVVMAVKDSKQVTVLQNLISMMQDKKITEEIQSSKDKTDILKIFKKN- +> +--LLFEELIELTLEAEDFEDAIKKIGEDAYRKGYVKEGFADAVIKREKLYPTALPLKVAIPHPME---RTVKKSAIIITKLKTPVDFTLMGTVPVNIIFTLAVNGKHQLTILQKLVGMFSEKESMERIKASTTPKEIMNSLIEL- +> +--LICPKLILCDVDAKDFQDALRQMAGHLKKEGYVEEGYLDMLLERERKFPTGLCFAVALPHTEP---DHVIKPCIAVAKLRRPVEFHEMVTVDVRFIFNLVLQKEQQLELLQKIISIFSDKEAMEQLEKEQEPEKIAEILEHT- +> +--YTNQEMILTGAKAESAEEIIRMLCGAAMKNQCIEPLFITALLEREKEYPTGLP-PIAIPHIHD-----CLKSFFSMAVTDTPVAFGCMGIIETRLVFLFGITDSYQTAVLRKFSNIFQEDEIMSGLLENDKPETLMQKMKEL- +> +--LLNRDLVHCQVAAADKNELLKKMSTAMHEQGYVKEGYIEGVLAREAASPTGLQYGCAIPHSEM---SYVNKPVISVATLSNAVTFNRMDVVDVRLVFMLAVDELKQVNTLQTLMLLLQDNEKVAELVQATNSDEILNVFDTL- +> +--LFSEDLIFIGQELRDRAELFKWFNGCMIEQGFVNESYYESILKREQQFPTGIQVGVAIPHADP---DNLNKPFIAVVRPKRGIEFEPMGNIQAELIFMLGVLKGDQVIALQKLMNLLTNNEAVQQLLEVRTCKEMMEIIRVN- +> +--IFNESLILLDVEGDSAEKILETVAQNLANQKLVKESFISAIIQREKEFATGLPVSVAIPHTDV---HHVIAKSISVAVLREPVDFGVMGTTPVQIIFMLSMDEHSQLSLLQNLMQIFQDGDVLKWLVNQKDKSEIKKLLERK- +> +--ELNDNLVFHNLKASDNIEVLQLMGDAMIQEGYGEEGFTEAVLKREKDYPTGLDIGVAIPHTDA---EHVKKEGLSIAVLNPPIEFDAMGRIPVKIVIMFTVAGDKHIDRLLQVLDMIKDEEILQGLLDAKNKKEIRTVIQKR- +> +--MIENKIIKLKVELKNSKEVLSSLADCLIEEKIVKQSFNKAILERENSYPTGLQYGIALPHTDS---EHVIKSQIAIMTLEKPVKFVEMAEIDVKTIFMLALKDNQHIKILQKVMELLQDKEAMTKIESFDDSKELIEILEKH- +> +--MIYRDLIYLDPTYTSQHDLFESLFQQLYEKGFVQASFLQAIEEREGKYPTALPFPIAIPHTDP---EHIIKPFVAVIRLRDKLLWKQMVVIAVKAVFLLGFHHEYHIRLLQKLMDLFSGTDFPDQLLKAENVEECYRLACAE- +> +--METSEFTLIGQSFQSKQEIINALFELMFKGGYVKTSYLAAVLEREDKMPTGLQYGIAIPHSDP---EHVNCSAIAIALLDQPVLFKNMADVPVQLVLMLAIAEGSVTSVLARLAEAFLNPAIMNHLSAMKTPQQLSGALS--- +> +--VLDENNILLDCSAESSEQAIRLAADCLYRNGYIGTQYVEDVLEREKSYPTGLPVITALPHAKS----DVLRTGVSAVRLLSPVEFGNMAKLPAELIFMLANAGDSHLEDLQELMECFSRVGLLRDLKVAETPAEFARIFAAW- +> +--VVDERLIFFRHRFKTYEEILEKIGSKAIELGFAKSNYVQGLKEREKEFATGVPVAVAIPHTDS---SYVNDNKVAIMTLDNSVEFNQMGKLKVKLVILLCFKDNNHMTALQNIIERIQDEEFVKSLLNSNNEQELLSIAEQN- +> +--FFQEDLVLPEITVNNSNEAIKQTGEVLHKAGFVSEEYVESVLKRESSFPTGLQLALAIPHATP---ENVAKNGIAVGRLTTPVYFQSMEEVAAEYIFMLALKDERHLEVLKQLFASLQKPSVIAALKGAKTKAEIMSVVEHN- +> +--MIETKLLYVQQQEDSVETIFKTICKKAQQLGYTKASYFNALQTRELSYPTGLACGIAIPHTDF---NHVKQPFISVMTLRKPVFFHAMDGVAVQIVFVLGLTTTAQLASLKAVMAICRSETRVEQLLHATDASELFAILTKE- +> +--QFVPELVKTDLEAVNQKEAITSLVTLLRKEGCVQDDYAGLVLEREQQYPTGLQAAIAMPHAFD---ERIKDSHVAIGILKDAVSFHNMESLNVHIIFLLAVGQHEQLEMLKILMGLFQEETMLQKMLATHSAQAICDMLNGY- +> +--TFDKQLIFNDLKIRDKNEILQYMATKMYEKGYVKGTYAQAVIEREKVYPTGLQFGVAIPHSDS---IHVNQAVIAVCIVEEPIVFHVMGEVLVKFIFMLAIDDKKHIEMLSKLSIIFQDEQKMQEIVKLKQ-DAIYEKLNCY- +> +--ALSRETCYVGVSGESSEEVLRTLSERLFQLGLVTEEYESNVILREQKYPTGLPRKVAIPHTDA----YVKETRICVAVLKHPVEFQVMGKVAVELVIMLAIKEKAQLGVLKELINVVQNGAMIEQLIGAGAGDEVYDILMSY- +> +--AFDRELVKLDEYYESQEELFNKIAAWLHDKELVHENYSEALKKRELEFPTGLHYDVAIPHADP---IHVKKPFIAFVRPANEIVFNEMAEVKPKIILFLGLMKEEQLSVLQKLMKLFSSEEFMTGCLQSVEDEKVFELLESA- +> +--ILKKELIRLAVEVADSEEALRIVAQGFVDSGYAKDTYPEAIVDRERVFATGLPFDIAIPHCDS---EHVIKPGVGIATLKDPVAFHMMGILHPKVLFMLALTEHGQLEMLQKLIGVIQDAELLEKIAACNDADALYGLMAPV- +> +--KFDETVIRVGIESVDCYDALDQLANTLCNAGYVKRSYVEAIIAREKIFPTGLPYGVAIPHADI---CHVNSSMIAIGILKDPVEFKNMGTVSTKIIFMLAMNNENQVKLLSAFMGNLQDQELLKNLAEAKNVHSVIKLIDGK- +> +--YFDSNLVFTDFEADNYEEVLSKLSNILLKKGIVKEEYPEKIVEREHNYPTGLEINVAVPHSDH---IYVNEGKVAVAILKKPVMFNKMDEIPVSIVFMLVVAEKAHLELLQKVFGAIQSQELLKQMLVIKDHQELTNLIKNN- +> +--MLEDKVIVFQKSLDSSEEALDYVSHLLLQSGAVKESYPNAIQEREKAFPTGLMYGVAIPHTDI---EHVNYSQMAIVSLKNPVVFQQMGDVEVNIIFMLALKEHQQVDLLSQLIELFQNKVLLKTLLALGNERSALGLLKAQ- +> +--TFDKRLIFRNIEIGGRDEILQYIAGKMYALGYVKESYVQAVIEREKVFPTGLPFGVAIPHSDA---VHVNKAVIAVCILKNPVMFHVMGEVLVKFIFMLAIDDAKHIEMLNKLSVIFQDRSIMNEIAGLEH-DTVYQRLTYY- +> +--LFIDDFCSASLKADSALDALTQIATLGYENNLVAQSWLAAVTQREQDFPTGLP-PVAIPHTDS----HVKQDGIGYFRLTQPVEFGEMGKIKVSVIIPLLITNKDQTSLLMSVIALVQDFEFMNQLILLDSKTQVANFLNEK- +> +--IISEESVFTDLQASNKEEALRVLADSLLEQGFIHDSFYESLINREVNAPTGLQMGIAIPHTDP---KHVKQDSLAVAVLDKPVVFQDMVSIEVKVIFLLGLSKTKHLNILKQIIELIKEEGSLEEISNMPQSDLYSYLSETL- +> +--TLDKNLFLTHLDAEDNLDALGKIADNLYNYNYVEKNYRQAVLEREEDYPTGLPPIVAIPHAAY---KLVKKTTISVATLSHPVKFHDMGILDVDVIIMMAIGQHGQVEMLQKIVSVIQDDSLRNKIFNAHNSTELYQLFNEL- +> +--LLDKKFIELDVEQSSRDSLLEYMGGKLLAENIVKETYPQAIVEREKEFPTGILISIAIPHTTG----HVNEPKIAVSVLKNPVEFCMMGKVNASVIIMIAINNDLQIDFLQRLVTLIENHELLLNIKNAASIDEVYGLLGFL- +> +--MTEIKVLALKQELNNAQDVLAYMGQQLEAMGAVRPSFIPAIQEREETFATGLQYGVAMPHTDS---DHVKKSTIAFMTLDQPVIFKQMGEVPVSLVAMLALADHSHLEMLQALMMLFQDQDLVKEAMAYSDSPEVLKLVHKI- +> +--LLDNLVVILDENYESDVDLFRKVIDSDKVRPFVKDSYFDAIVAREEEYPTGITIDFAIPHTDP---QHLVEPFVAVVRPKESVQFNPMGKAEAKLIVMLGIQKGQQIEMLQKLMAFFMEESAIDSIFKTNEEEQIRTKMHKV- +> +--ATFRELILRNVEAKNAEDAIRQVGQRFFDAGFVKDTYIDAVLAREVTYPTGLQIGVAMPHTDP---QHVYRPGVCIAQLAHPVTFAHMGLVEAEMLFMMAIQDDEQVELLQKVLGVFQQPEVVAEFRAAKTDDELFAAAQKY- +> +--LLHEELVLLNYQADNAETLLKELATILQQQGYVKDSYIQAILAREKEFPTGLNVKLAMPHAAP---KHVYKEAILVAKLAQPVMFKEMGDVEASLIFMLAVQDKNHLDALSKLMSIFSQKEKLLEVYNTVDKKRLIEKLNAV- +> +--YLDKDLIFKNLDVKDYKDAINTLASELYKKGLVKQDYVKEVLSREEIYPTGLYINVAIPHCDY---QFVNKKSIAVGILKNPIKFKKMDDVEVSIIIMLAIDEDNHIAYLTKVFNLVQNQELLKELYLSVSEEKILELLNKN- +> +--AIYEDLVVCGVDAADAEDAIRQVGRFLFRKGFVKDTYVDAVAAREKEFPTGLQLAVAMPHTAG----HVNTPAVCVAKLAHPVQFAHMGEVQAELLFMMAIQNDAQLETLQKVMKVFTDEAAVAEFKAAGDRESLYQAAKRH- +> +--MNNSEIQILKLDVSTDKEALKYMGDFLVFQGVTVKAFPEKVIEREATLPTGLPIGVAVPHTDS----YVKKRQLLISPLKTPVVFRQMGEVNVSFVFMPAIPDGEHLTLLRQLFTCFEDNQFTEALINWDGKKSLKRLIQRN- +> +--FFDRKITFFELEVDNQEDALKKLADNLYTANLVTSSFHAGILEREKDYPTGLGYGVAIPHTNA---DKVIIPQIAFASLKSPVKFRMMGEVDVSVIFMLALNKEDQLAMLQKLMEVIENQALLTEFARCKNQDEFEKLLERI- +> +--MDNSEIQILNLDVSTDKEALKYMGDFLVFQDIAEKDFPEKIIERETELPTGLPIGAAVPHTDS----YVNKRSLLVSPLKQPVVFRQMGEVSVSFVFMPAIPEGDHLTLIRELFTCFEDDQFTEALANWDGRKALKKLIQRR- +> +---MLNDVIVIDGEAKNWKDAINLTFNELYKKGYVKPSFYEACIEREIKFPTGLNIPVAIPHTDA---IHVNKQAICVLRLKEPVSFYSIEKVDAQFIFNMALKREDQLTLLKAVINIVQDKTFLEKAKKLNLNEVKNLFYKKW- +> +--MNLNDILMMDLTVDTKEQALSAMSSMLINTGYVTPNYMEAILKREQSFPTGLPYGVAVPHADS---KHVIESQVVFAALRRPVVFQQMGDIDVSFIFMLAFRDTEHLQHVQKLFLCLQDTTFMQQLNQIKKKSHLLQLINNI- +> +--PLEVKNIYVKRNFSSADDFFKVITSKLEKEGMIKEGYYNAITNREKTYPTGLDIKVAIPHTDC----FSNKTQLIVTTLEKPVKFKRMDEVSVSVIILILFDNNKQLKLLSEIMKIVKNQELLAEILKAKTPEEVYQLLNQ-- +> +--TIRKDMVFLNQDIASSDELFEFIGEKAQEHGLVKDSYVQALKDREAQFPTGLQVGVAIPHADA---EHLNEEFIALVTLDSPVEFHSMETVAADIVFALGLTKEDQLETLQTIVQIIQDDNKISNLLEAKDVDEALNALK--- +> +-----MHILVHDLEVKTYQDAILTSGEYLLEKNYITPEYITACIDREKDYPTGLLIGIAIPHGNS---QFVKSDSISLVRSSKGVIFGQMAKVTCQLIFNLALATDQHLSILRRLVTLFQDESFVSKCQQFN-CQQTEELITQQ- +> +--MINIDNIYLDVKEENYKDILKKIGDILYKKGYVKESYTKSLLNREEMSPTGLPWSIAIPHTDP---EHVIKPCIIIFKLKNIVKFKEMADVNVKYVFGLVFTDKKQLPLLSNIISITQDKDAMEMLLNATTKENIFKTVTKY- +> +--MLSDKIILLDEAASDNQEALGQIADQMTRSGAVKDSYKSAVLKREIDFPTGLAIGIAMPHTDA---EHVNYDQLGVLRLREPVSFLQMGRIQVKFVFMLALKEHTQLAMLQKLIALIQDKASIRQLLLAEKTDEIVETLNNV- +> +--MFSEELIYLNESYHSQNDLFNRISKDLFEKGYVHDSYQEALKQREIKYPTGLQCGIAIPHTEA---MHIKKQAIAVVKLDETILFKEMVDVSIKLLFFLLVKEESQVQVLSNLMSLFSNNQFINDLLQSESKIQILETINNE- +> +--MLSKDLVFLDVEYKTSDEFLKSIADKLFEKGYVKESFKDAIIKREEQYPTAIGYNLAIPHTDS---EHVNKPGVAFVRLKNECEFKEMCDINVNMAFVLLVTQEEQVSLLSKLMELFGETEFLESLYKEQDPSVIVDVLNNK- +> +--MLKKEYILRDMDCSNSEEAIRMLADVLEKDGAVKDTFCKAVVDREKEYPTGLPFDVAVPHTTD---SHVNRPSIAVGFLSKPVMFRQMGELYPEVILMLAISDEKQLVLLKKLMVFLQDENALKSLKASSTKDEVYEIVNSY- +> +--MFQKEDIYLDVDAKNYIELFEKMAKVFKEKRYVKETYLKSVLEREKKYPTGFEYNIGLPHTDA---EHISVQKIILIRLKNEIEYREVVKIPIKIFIMLLIKNEDQTTILGKLIEIIGEKEFYRKVSEAKDLKELYE------ +> +-SILDISGCKLKMTAGNRNQAMEMMAGLLAENPAARQALLEGMLQREELGTTAVGNGVAVPHCRL---DEMKGFALALSVCGKGVNWNSLDGRSVHIIAAIAGPSEEHLRLLAGTARVLGNGRARYELLNSETEFAMREAFL--- +> +-NYLSPESCTVQLEGRSKAEVLSSLADLICRSPDLREAVLKGLLERETMGSTGFGKGIALPHCKV---EGMERFALALGISSKGVSFDAMDGRSVHVFCAIVGPPEMHLRLLAAASRVLGTGNSRYEMLSSTSAYALREAFL--- +> +-QLTEKKCCKLGLKGRTKEEVLRKLAELAHKSEKLQDDVFEALQKREEQGSTAFGGEIAIPHARL---DEMDEFLVFFAVAPKGVEFDSLDKKKVKLIFVILGPSNEHLQILAAISRIAGIPAIRNEILRAPTETAMYEAFI--- +> +-DILNRDLCRVRLHARRKEDMLNEIAEILKEHDALQEQIAAALREREQLGSTGFGDGLALPHCRL---PGLKQFVLGIGLSPRGAAFDALDGKKAHLFCFLAGPENEYVKVLAEISGVLRNESARRELRKAPTATALYESFM--- +> +-DFLSEERIRPALRARERVGVVYELAELLALRGPVQGVLGRLLLERERIAGTVLAGGVAIPHCRL---EGLPRITACVGIQHEGCFFGEPEEGRVRIFVGLVSPMGLHLNLLARIAGMLREPSLREELLATPTAAGILQLLVQ-- +> +-EHLSEDCIVPTLWSGDRKGVLHELAGTLAASTGAPRKVEGLLQAREHLCSTAIGEGIAIPHCRV---ERLRHVTACVAVHRSGVDFGARDGLPVRLWVTLVSPAGAHLRMLARIAALLRDARLRQSVLAAPSAAAIRSLFIR-- +> +-HLLLPEHVLLDIPARTREEVLYFVAQALERSGLNSEDLVDHLLEREKLGATVVGHEAAIPHCKL---PSLKQVVVAFARTQEPVPFGPEPKDRARFFFFVLSPPAAHLQVLAEIARLLRDRDVEAGLAKVKTPQELLVLLAK-- +> +--KENEKFLYYSFDEEEKEALLAEMSAVLIDAGFVYESYQPAVIERERVFPTGLGLSVAIPHTDS---DHVKKEGFLVGVLEKPVRFEMMASLEVELVFMLAIKEEDQLAMLQKLMLLCQDEKNLQLLKSKEKVVEVEQLLKTI- +> +--IFHEQFIYPKLSGTTLKEILDKVSTDLLIQGFVKESFSQAVLEREMHHPTGLKIGVAIPHTDS---SHVTQSVISVITLETPIPFTIMGSTNVQVLFLLALQDKQHIQILKEIMKLIQHPQRLQQLATAATKSEIIESISTL- +> +--KFDEDMIMLNICASSSKELLKELSQVFYDRGYVQDSFKQAIVKREEQYPTGLSIGVAIPHADP---VHVKQESLAVGILSDAVIFNEMTSLNVEIIFMLAITDGQHLIMLQALSEILKDKEKLSSIRYAATKEEVFQCILPY- +> +--TNEKNIFV-NMEVADFPELIHKIAQPLIEDQDVVVEFPTQVIKREEGFSTGLPIGVAIPHTDA---KYVKNNRVTIATLKNPIKMEVMGGIDVSIVFLLALGQNKQLNILKKLMGILPDAELLKKIKNGTK-EEIYQLAKDE- +> +--YFLVEECYFDVRVQDFAELIAKFSQIFITKGYVNVDWAQSMLTREKNYPTGLAHCIAIPHTYS---EFVQTSLIVPVVLQQKIPFVHMG-IDVEVIFFLLIKEHQQVDVLAKILNLCSQKNFITELKTAKTQTTMYETVLRN- +> +--YVYPELIWVNKSFADKEDLFKTVAQSLYNKNFVTETYYESLLAREIKFPTGLDYYVAIPHSEC---GNIKKEFISVVVLEKPVTMNKMD-LPVEYVFFLGMNNQDHLKVLKEVITIIQNKHLILEMKKTSSPDQIAGLLTKT- +> +--FNEKLIFKLSDEIDSKEIALSFLAEQLYAKQYVTEGYKKGILEREKIYPTGLGINIAVPHTDC---IHVRCDAFAMGVLSKPLTFYAMDDIDVNIIFMLALSQHGQIAMLQKVLALVKEQEQLKKMINCKDVKTIYDICLKY- +> +--NNVTRCLIKGMEFNTRKEVLEYIGNYLFKKGFVKESFIYALLERERVFPTGLNINVAIPHTDA---DHVINPAIVVMVLNKPIVFETMGSVKVDVIFALAIQDKKQLSLLQKLMELFQNEERLKHLIDVSDIEEFEQIFSIE- +> +--ILSNIEVLNLNHATSREEVLTVMSKVVIEKGYATPGFLNAVLERERNYPTGLGVEVAIPHADP---EWTLKPSLTVGVLQNAVEFEPMG-VQARLIFLLTIADSEHLNFLKAFATLVEDEDTLVEFEKNPDIHYLLGRLQSA- +> +--EFDPGIIRPNVNVNNWEELLGKMGDLLKEKGYVKETFKEALINREKEHPTGIELGIAIPHTDA---VHVNKTTIAMVTLEKPIKFELMA-TNAEIVFILVVKEKTQLFFLKRLMAMFQKIEVLQKIKEMKESKDIINLLKQE- +> +--V-QTDHLFIFPDETRQDVILEIMAKSLWSKGFVHESYVNAVKDREKHYPTGLADHVAIPHTDA---CHVKQQTIALGVVKQGTKFHCMADISVKLIIMLAIEKEAHLEMLEEIMTFIQDASRLEALSQASTPIEFFSVIQPA- +> +--YLDEHLVDLEMDE---FSALAALADRLEENQCVNGAFSLAIQEREKEFATGLHIGVAIPHTDS---EYVFKQSMAIGILKQPVMFEMMGSVPVKIMFMLAIKEKKQLEFLQALIDMFQTDEKVLAIIQAKSAAEAVKKMKQN- +> +--YLDEQLVDLAMDE---FSALATLASRLEANQCVNGEFSSAVQEREKEFATGLHIGVAIPHTDS---EYVFKQSMAIGILKNPVMFEMMGSVPVKIMFMLAIKEKKQLEFLQALIDMFQTDEKVLAIIQANTAEEVVKSIKQN- +> +--HFRRHYVQHLPQGLSVEALIHQLAGPLINDRMVVEDFASHVIAREAKFPTGLPVGVAIPHTDH---KYVRHNAISIGVLPKPVIFADMGGVAVQVVFLLALGENKQLNVLGLIMDIIQDGEFMQRLLAMDD-EEIYQSILTK- +> +--QLNVDLMMVQAVVGDQIDLLIEMGDRFVAGGYCKPMFTEAVIHRERLYPTGIRIGVAIPHADS---EFVIKEAVGFAILKEPVCFQQMGGLAVSMVIMLAS-MRDHIDLLQCIVSLLQDNVVLDRLLGATEENEMIQIIKKW- +> +--TLDRDLIVMDLQAENKETVIRAVVDKMVEMGYVGPDYYDEVIAREKDYPTGLGVMTAVPHAFC---STVKKTGIGVAQLRTPVLFQNASDLPVKLVFVMANAQGEHLSGLQDLMDVFCKKQMLLDLYASKTPEQFMEIMESG- +> +--LVHKENIMLNLSATDKESVLSQMSDVLFQNGFVKSTFKDAVIDREKEFATGLLCSVAIPHTDV---EHINHRTIGVAVLEKEVPFIEMGTTEVKIVFMLAMDKDDQLKLLQQLMQIFQSEEKLEQILRTKDETILATLINDY- +> +--NIEKGYLVAKVAATDKFGVLREMGNVLVEKGWVKDTYPGAVIEREKVFPTGLAMGVAIPHTDA---IHVNKKAVFCGILDKPVDFVVMGDVSVEVIFMLAIMKNDQIEMLSKLVETCQNVSVLQTVKAAEDMDTIEEVMEKL- +> +--YFKEEMVLF-SNEQDKENLLSEMAEQLIQVGAVKPSFKEAVIKREAVFPTGLHAGVAIPHTDS---EHVIRPVIAVRILETPVSFIEMASIEVKVVFMMALKSDEQLDMLQTLIQLIQDEEVMTTLLEAKETTNVLTAIEQF- +> +--MMDTSLVFLDADFSSRDDLFHTMGSWLKDNGYVNEDYREAVCRREEEFPTGLGHQLAIPHTDS---EYIEKPGLVFVRPKNPLAFQEMC-VDAEMIFLLLVKDKDQMPLLSGLMARFGDGELMDRLSRETDPEVIADLLDHC- +> +--FASELFVSLDVTKENLQELYQDIGNELVEKGMVMSDYGEQLQQREANFPTGLFGNVAIPHTDA---KYVKKPFVYAIRLTDEVITKRMD-IPVKLLFVLGFTKEDQLVLLTKMMQALNNESISNQFQQVDSPERFKEVLKEQ- +> +--NTDKHYLAVSLSGSDDKEVLGKMAEAMFQEGYVTEGFHDAIIQREENFPTGLEINVAIPHTDP---EYVKKPAICLGVLDQPVEFCVMGMTRVSLLFMLAIKKEDQLGLLQKLIEACQDQEVLKVLRSGS-VDKIDEVLGDL- +> +--LIDAELVRLHMVAQTPAEVLGKLADTLFGKGKVKESYKDAVLQREIQYPTGLGTCVAVPHTDS---SHVLEPALAVGILQQPVAFQMMGSLPVEIVMMFAVDKEKHLTVLTQLMTMLQDETLLTKIKQATAATEVCSLLSGL- +> +-----MEFVFISDKADNWEDAIVKTSRALFDAGFVTEEFGSQCIKREREYPTGL-IPIAIPHTDS---AFVHTSAICVLALESQVPFINMEDVPVEYVLNLAIKDKNQVTILNKVLQVFNREGLPEQLERKGN---IMQAFVNA- +> +--IFKKDLVDLSTNAESAEELFRESFAVLKNKGYVQDDFLEALNKREHDYPTGLNIAIAIPHADP---QYVSKPFIYIQKLNNKISFKHMG-IFPELVFTLGMKEEKQLELLSELMEFFTNEKIVEELKSINNEEKLLYLLSNN- +> +--LKKDYIYDL--RAESRDKLFEIMGGRLEKEGITKNSYVAALKEREEKYPTGLGLLIAMPHTDS---AHVNEACISIARLENPIPFHEMGNLDVEMVFMLALKDEAHLKILQKIIGMFSDREVLKKLREAETAEKIYQVVYEA- +> +---MNENLIFLQSGIETAEEALTYLGNRLREQQFVKDTFVSAIIERENIFPTGLGYGVALPHTDA---KHVTQTQVAVMTLEKPVTFTQMASVAVQLIVMLAIKEHSQLEMLQTLMGVLQDRDLVQDILACRAQDQVLELLSSH- +> +--EMKTRYLVIHGTADNNEQAIKLCGEALYKAGIVSENFGDLCAKRERDFPTGL-IPTAIPHVKD---EGITENAICLLKLNHPVTFKRLDDVKTDMIFNLAIRDDEHLAVLQKMMAFLNNPEVLTKCKKLSNEETLES------ +> +--FVNKDLVFLNQEFDTNSELFEFVGAEANDLGVAKESYADALKEREANFPTGLNFGVAIPHSDS---IHINEEFISVVTLDKPVQFSSME-LDVRLVFVLGLKKEDQLSILQAIISVIQDESKVEKLISAASSDEVLEILENN- +> +--LVIPELVFFGESFDDQEDFFKKSSKKLLELGYVTEGYFKAVVEREASYPTGLNISIAIPHTNP---EFIVNPFIAAYHLRNAVAFTQMA-IQSELILALGIKEQEQVGMLSKIIEVLNDPEFVKEYQSLSNQEQLVKLLKSK- +> +--ILNKELVKISLDAEKFSDVIETLGSLMYKQKSVKDTYINAVIEREKVFPTGLGMCVAIPHTDS---IHVNKSCMAIATLKNPVEFSMMGNLSVNVVFLLAIKDNNQLMLLKNLMLLIQNGELLNRLKDAESVDKVLEVLQFC- +> +--L-NKEHIVIMDNCEDWEKAIRLLGDRLIRTGTVGREYIDRVLEREREYPTGLGGNAAIPHADS---AGVFRPGLALGVIRQGVGFREMVSVRVQLVFLLAAVSEGQLGLLQGVMELLQNRSIRERILSAEREDQIAGILGKR- +> +---MKEPLLYHRLSVATQRELFEKLSTELEVEGIVQQHFLEALIERESEFPTGLKIGVAIPHTDG---TYVNEDRLVFVTLEQPIPFNEMGGIEVSVVIMLAIKEKNHLSILQKLIESLQKEGFVEQLAQAEDVNKMETVISAY- +> +-LVIKRELLFSKMKPQDYEEMISFLGGKMEELGYVKNTYVPAVLEREKGFPTGLQYGIAIPHTDR---EHVYQSALAIATLAEPIEVCSMINVRVSLVILMAVEDDGQVKMLSKLMGLFQDVETLKRLEHASSVEEMYNIVAKM- +> +-ILFDSDMVVVGQPFPDPEAVIADLAGRLAARGCVGPGFLEAVKDRETRFPTGLPVGVAIPHTDP---EYCLRPGLAVAVLPQPVPWRAMGTVDVRVVFLLALPAQKHVNFLSQLVQLFQSPDALTQLISLSDPAAVADFVRCR- +> +-EYLQYSPILLGEQYQNKKEVFTAVYNLAKQKGWVTKDFGKKILEREEIYPTGIDFGIAIPHTDP---EWVKEEFITLLVPERPVLFQRMDDVQVDFIFILGLNQHEQLAMLQNLMQLIQNTALLENLYKQTKREKLILLLQDY- +> +-RMVYSELILLGLDVPNAEEAIRRLGARMVDYGYVRETFVDAVIERERTFPTGLPIPVAIPHTDA---VHCCRPAIAIGVLTRPVTFGEMGNVDAKVIFLLSITDSQQVVWLQKLVEAFQHPHFLQHLVKSRNTEEARSICQEV- +> +-ALLNKNLIHRNATFLDADDALKSMATTMVKNRYVKASFVDAVVNREHQFPTGLPIMVAIPHADW---TNVNRGTISVATLKEPVVFKNMGDLAVRLIFMLAVSEHAEVTLLKDLMGIVQNQATLQGLLDAKSDDELFNRLEDM- +> +-DHIEHEAIALNVEATTSEAIIRLLADRLARLGHVRPSFAEAVLAREAQMPTGLPANVAVPHTDP---EHVIRPGIAIATLARPVDFANMESLPVGIVFMLALNDDRQIEMLQQIMETIQDDDLVDALLAARTNDQMLALLGRG- +> +-LYLNEELVFRNVEASTDSEVLAYLAGELYQKGYVKEEYIQAIQDREKEYPTGLPPGIAIPHANY---EMVNKTTLAIATLKEPVLFHNMEDLPIQIVIMMAIGEHGQVEMLQKIVGIIQDEPLRQEMIDARNDTELLALLKKA- +> +-ILIDADLIEINMDVSTKEDALLSLSNRLLEKDLVEQGFYQHIIEREEQFPTGLPIPIALCHTEA---IHVKKSALAVATLKRPVIFQEMGTLDVEIIFLLALKDKDQVHWLKKMIGVFQKEEALHKIRSASSPNELSLYLSQV- +> +-EIIMRDLTALDLDAKSCEQVFDIMGARFLEKGYVNERYLPTIKEREAQYPTALPYPIAIPHTMA---DAILKPFIAPVRLKNTVKWGDMSDFDVKLVCMLGFKDGEHIELLQILMHNFQKSEWANPLFSAKTEDEFFEAFNSM- +> +-QFITKDMIWVQTPCRDQDALFEMVSERAASQNRISNQFLEKLTEREAVFPTGLQYGVALPHTDP---ECVTEQFIAVLTSEPGIRFKQMADTRANLIFVLGLNEHSQLAVLQQLMGAIQNEKHVKELLAAKNEDEVIETLSQV- +> +-DYVKKDTIFLNCQAQSRAELFSKVSDKLLNEGYVKKGFLDFINHREDNYPTGLQHTVAIPHGDP---QFINKPFVAVITLTKPITMRRMDDLPVDTLFTLGLTNSDHLDLLKEIMKLLQTDSFVQQIKNCTNKDEVETVIRVA- +> +-FALVPELVLVGIEASNRCEVLATMSGNLFRQGYVQESYIQAIQEREVHYPTGLPIGVAIPHTDA---VHVNRAAVSIGILKKPVLFQMMGNIEAEIVFMLAIKEQEQINMLQKLSSLFQNRTLLSNLRKAVEREQAVSLLNQA- +> +-QIVRECILPH---AQQKEDIIQELSKRMKERNLVNADFQEAVLKREQKYPTGLLRNIAIPHTEP---QYVKVPCIGIATLKKSVAFHRMDAVDVDVVLLLALNQHAHMEMLSRIILMCQDEAFIEELMRAEQETDIEQIVRER- +> +-DYLRDELILPQRELTAQQELFRFVNEVALENGYVNEQFLPKLIAREEKYPTGLEGAVAIPHTDA---DTIVKEFVAVITTKEPIEFHRMDDVRPRLFFVLGLNRHAQVKMLQQLAAVIQNHELVTLLEQAPTPEAIRATLE--- +> +-PFLKEELLKLNSVCKDQADIFEMVYKEAFGKGYVSENFLTKIKEREASFPTGLQYSVAIPHTDP---EHVFEQFISVVTLQKPVSFYLMDDVDVRIVLLLGLNQHTQLTVLQELMQAIQDQQKIEQLLQAENQRDVQAIFNGV- +> +-SLLKKEMVWLDACFENRLEVFEAVGMRAQHLNLTEETFSTQLELREKEFPTGLAYGVAIPHTDA---VYVKEPFIGILTLEKPVIFQAMDDVEVRLVFVLGLAEHTQLAVLQELMKIIQDKERIKKMLSTQTIEEMLATFHQE- +> +-MNIKPEYMMLNIKASTDVEAIKILAENFFKAGAVKDTFVPAILLREKNFCTGLQAGIAIPHTDA---IHVNYPAVAIGKLENPVVFQSMGAVKVEIMFMLAIKEHKQIEFLQLLMTKFQEENLLRRLMKCNTAEELTEKFIAC- +> +-IKIFKEAIHTHLNVNDKAELISILAKPLLEKKYVTAEFAEKVLEREEKFPTGLPIGVAIPHTDP---KYVLKNAISIGVLKKPLPFKVMASVNVGIIFLLALNDEKHLEILQKLISLIQNEKALFQILNGSKDEIFHFIDRQL- +> +-EDLDKKLIHLQAEAGHANDIFDQLGTCFINEGYSRSDYVEALKQREAQFPTGLDFGVAIPHTDA---GYVLHETEGIMTLKHPVTFIQMGSVEVKVVFMLAIEDKNHIKKLQQILRIIQDNAVLEKIYRASSADEVIDIVKQK- +> +-QLVREDLINLQVKANDKSQLLEILSDDLYQKGYVLDSFKEALIKREREFPTGLQIAVAIPHTYA---QHIRAPFIYINQLEAPVSFIQMGTVQVSYVIILGISKQEQTGLLAELMEIFGNADFINQIQMVNSKKDLYNLFKTQ- +> +-EYIGKDHIRIFEESVDQSELLHQLGDMLIRTGAVRIEYMEAVCKREQAFPTGLYVNVAIPHADPE--HHVMKPTIALGVVRKGVPFRNMADISVQLVFLLAPERETQLVILEQIMNLIQDQANMRKIMDAQGIEDVWNVLGQL- +> +-SEYFQIETIFSEQ-TNQTAVLCEMAELLIKKGYVKESYQDAILKREKTFPTGLMGGVALPHADS---EHVLAPIVCIAKSKEPIYFHEMAVVPVHFIFMLALQDSEQLDMLQFLIQMIQNEEVMDSIANSEQATEILDAIHAF- +> +-SMINPELVFTDLPCTDRQTFLQYISRRLEEKDYVKCSFEGAIIEREKKYPTGLPQHVALPHTDV---QHAKNPIIVPVKFRTPVVFKEMGNIPCSMAFVLVVTEEKQIDILQSLINLFIKKDFLEELYKEKTREGFLKRLLDE- +> +-AITSEQLVWIQQDFTSREALFSFMSQQLYEKGYVNEGYQEEIISREEKFPTGLVYNVGIPHCDS---QYVKKDFIAIVILSNYIQMNQMDKIPVKYLFFLGLQDNNHLKILKKIMKVIKSEQLIHRAENSQSVKEISELLKIE- +> +-ISFDVSFVKHIDDGFNFGQIIDELSKNLLDKKLVTKEYPQAVKDREIKFPTGLPVGVAIPHTDP---KYVINNAVSVAVLKKPIEMTVMGTVEISIIFLLSLAQNKQLNILKRIMSVVQDQDLLQSFALASN-DEITRQVRKA- +> +-DMISEKLIIFSNKANKKEDILLEMSELLSKNGYVKNSFYDGIKNREESFPTGLIGNVAIPHTDS---EHVKKPAIAVAVLKSPVNFYRMDDIEVDIIFMLAIKEENQVGVISNLISAFKGSNLLGDLKKSNSKEEAFKYMKNN- +> +-LKFEEAFIYPKLDAKSYEDAVRKMSQNLLKEGYVTSEYPDQVLAREKNFPTGLVMNIGIPHTEA---EYVKKTAVAVATLREPVKVHSMIDLPVSMMFMIAVSDKGQVTILRELMRLFQDQDLMEKIMSEDTASGIYKLLKPN- +> +-SIYYDAVI--LEDMNSKEEIISCLANYLQQKGYVNEQYQAATLERELEYPTGLPIGVAVPHSKT---ENVIRPAIVMAISRKLVEFGEMGNLQVGIVFMLALQGNRHLNFLKHIINFCKQESNVTRLYQVPAREEAYRIFQEE- +> +-HFFSDRVIIFDQTFSDRNTALKSVADQLLKAGAVVPTFEKAIIAREQTYPTGLQIGVAIPHTDA---DQVIHDQIGFVSLKTPVEFRQMASVSVNYLFVLALKTHQQLDMLQKLMGLFADDAEMTAFRKIKTADDFIHFMTEQ- +> +-SRIDEKLVKVGVQVPSREALITAMGTMLVEQGFVKPSYIPALLAREKEFPTGIAVGVAIPHSDA---GHVLKTAASVWVLDKSIPFHVMGGLEVNIVFMLAVHNQEHLMFLQKLLGLFSKEDVMLKLRNAANATCIAETINLE- +> +-ELVKKKLVFPNIRVDTHEELFRFMFTALQDAGCVKQTFLQGVLDREAHFPTGLKFGCALPHTDL---EHVITPAIAVATLKEPVLFKSMEDVPVNLVFMLALNKEDQLLALKQLASIIQNDALIKKLIDANDQESLFSAILEV- +> +-DKVREDLILLNVEGDTRDEVLNNISIALLEKGVVKKSFASALIKRENEYPTGIPYNVAIPHTYP---EHNNEIAVTIAVPKKPVQFYNMGNLKVYVIICLSFEKDDSVKMLSSLMTFFGNEENVKAVMVCRDTSEVLKVIRSS- +> +-LFLEREMIFPKLEFDSRTEVLQYMAHQFTKLDLAKESYAAALIEREAHFPTGISFDIAIPHCAS---ENVNRTSMAVATLTHSVGWHAMDDLQPTVVFMLAIKDDKQIETLQKIMEIIQNSQLLQDISVAVTRDEIFSKLDPI- +> +-DLLAPTAVCVHLDAADWRAVITALGQRLHAAGCVRATFVQAALDREAQLPTGLPFNAAIPHTDI---EHVITPALALATLARPVEFRNMIDVPVQLVILMAMEEKSQVEMLQEIAGVLQDPDLIAQLVAAGDEVAIRRVLEGV- +> +-AYVKEPLVFTQENYFSQDELFEQVTQKAADLDWVRDDFLERIKKRETTFPTGIQYGAAIPHTDA---ECVHEEFVAIVTLQDPVIFQSMEDVKAQIVFVLGLNQHAQLEMLQSLMGLLQNESLLAELLLATTPSELIEIIKQN- +> +-DLVKDELIDIAQEDLEYKEVISYLGNLLLKNNYIKEDYIKDVLLREEIFPTGLEMGIAIPHANP---DNVLKNGIAILKLKNPVRFSNMETVYVNIVFMLALKNDDHLKMLQSLFLMFQKEEVMDELGKVQSEEYIKIIMLKN- +> +-NYLNENCILLRPEVDDKFKLLGNMSDLLMREGYVTEDFGQRVIEREKVFPTGLPVGFAIPHADV---KYVKKSGLCIAILDKPISFFRMDDIDIDFVVMIAMKNDEQLKTLQSLIDSFNNIEGWLELRRVSRVQEAIERLKEL- +> +-VYISPELILMNIEAKTDQEAIEILAKHLYEKGIVKESYIDAVKEREKVFSTGLNMGIAIPHTDS---IHVNRQAIAVGILKEPVKFCHMGMVKCEMMFMMAIEKESQVDFLGRMMDIFQSEGYLRGLKACATPEELAEKFGKS- +> +-ELFHQHLIFSNLKCETAYQLFEKVGSCLHKENYVKSSYLSALTKREETYPTGLSINIAIPHTDC---EHISSPFIAYANTEKPLPVGSMGELQVSHYFFLGITEKTQVELLQYLMTLFTNHQFVQGLKHAKSEEEIFQVIKYP- +> +-MFFDEKVFEDIQGLESSNEVLQHLSDKLESLGIVKNTYKQAILKREEEFPTGITYGIAIPHTDA---EHVIKPQIGVMTLHEPVEFVQMASVEVNTIFILALKEHSQIDILQKLMTLLQNTEVMEKINQLKNTDEDKEILKEI- +> +-TLFQKELIKLNTEFHSSDDMFVALSHDLIKNGYVEDTFNQAIIEREKEFPTGLSALLAIPHTDT---KHITKPFIYVVKANKPMKFLQMATLEVNIIFMLGIKDAKQVGLLSVIIDKFKDEQFVHTFQSISNEKEMLAFLKNN- +> +-DYLDENLIFTNKSFSTSKELFETISDVTLALGNTREDFLSRVIDREANFPTGIQIGVAIPHTDA---ECIFKEFVAVVINQSPIPFKSMEDVQASLVFVLGLNQHEQLEMLQSLMGLIQNEKLLFKIVAATSAEEVLTIVKTN- +> +-NLFREDLLFVDMNSDSLEDVVKLIGKKMLEKGYVKESYVEAVLEREKKLPTGLEGGVAIPHTDR---QQVNESVIGVATFKEPISVYSMVDIHANLVFLLAIKDDGQIEVLKELMNLFKKPNLLKKMVEASTQKQLEDVTLNV- +> +-GLINEHLVFPDQQFADNEAALRFLAGKLNAAGKVHDDFFDAVWAREQKFPTGLPINVAIPHADA---KYVKESAIAVATLAQPIPFHNMAVIPVSLIMMLAIHEHGQVQVLQNVMALFQDEQHLAQLLQEHDAHALFTDLDKT- +> +-IAFNESLILEFDKPMTDREVLSAMTDYLCEKGIVKDTYKQAILEREQSFPTGLKINVAIPHADI---CHVNEAAICVAVLKTPAPFRAMDEVPVSLVIMLALTEHGHIEMLQRIVKLIQNQEDVKHIVEAGQPDTIHKIIKQY- +> +-VIVPKIIVNTRLQVGNCKEIIERLGVQMLEAGYVKDTYIEAVLQREDILPTGLKVNVAIPHTDV---THVNESAISMTTLNRPVKFYLMEDIDVDIVFLLAVKEEEQVQLLKNLIAIFQNEELLAQMKDIEDENSLNQVIKAS- +> +-ELLKPELVFFDIEAKDAFELFDQLETRLTNLGYIKDTWKDAISTREKNYPTGLAGEIAIPHTDP---VNLEKPYIAIVKPSSTINFEPMGGVPAKLVVNLGIMRGGQVEMLQSLMGIFMDEAKSADVFGQTTADGMVASFSKY- +> +-DLLKRDLVRLDWEVKDQEDFFDRIATELLRAGYIRESFREALVERERKYPTALPEAVAIPHSDV---EHIIRPFIASVRLAKPIDWREMGNHPVRFIFVLGFVQDRHVEVLQIMLQAFQDPAFMEQLSEAQTPDEYYRVLSGM- +> +-LAKDSLLTIIGMPQQDRYEVLKVLSDSLKEQGFVTDGHYDALLKREMHFPTGIPFGIAIPHTDP---AYVRQAAIAVGILAHPVVFYQMGAVEVQMVFLLALTQNKQINMLQNITRLIRDGEALAFIRHSTSREEIRNKLQSF- +> +-ELIENGKVY-FCDFTSRDDLYAYLADDLYAQDYVQDTFLSALKEREATFPTGIIYNIALPHVDA---VHVKKNALIIAVLNHPINYVRMDKINVKVVFMLLIKDSVHTQAISSLAKLWFNQTFMNAVLSVKSKEELVALVKQA- +> +-VELKKENILTNLNFQTKEEVLRFLANHLYEEGYVKEEYKKSIVEREHRYPTGLPVNIAIPHTNH---DLVNETTIAIGVLDKPVSFYSMEDLDIQIVIMLAIGEKGQIEMLQRIVAIIQNEALTKKVLASDSTETIVALLEPA- +> +-KFIPELVET-NISAKNKEEVIRFLAKKLADRKCVSSHYSELVLQREKEYPTGLIAVIAIPHAFD---PETKGNNIAIGILKTPVGFKHMEDVPVKIVFMLAINGHEHMEMLKILMQLVRDEELFKKLQSISSKNEICKLLNEY- +> +-EILDTKLFHIRLDVKDRDELFETMASGLVDSGRVKPSFLRGLMDREEIFPTGLPGGVAIPHTDA---EHVLLDSISVATLIHPVGFREMAGLPVDVVMMLALADGSHLDVLQQVLGWVRDGEFIDRLRGCLDEEEAFTLLAGR- +> +-DYLVPDGVVLGCDAVDANEVIGLLADHLQKAAIVKSTYGAAVISREAIMPTGLPFAVAVPHTDP---EHVISSGVAMATLSRPVMFGSMDDIPVSVVFELALRSDEQIEMLTAIGQLLQDEGRLRRLSNATSKEEVTSILNST- +> +-CYISKDLLFLNTNFSSTNELFQAVSKRGLKYGLVNDKFLPSIVQREAKFPTGLEVNVAIPHTDV---DTIEHPFIALNTNSQGISFCRMDDIQARVIFILGMKEHAQLELLQSLMNAIQNPNTLNNLVNAQNFDDVLKVLQDY- +> +-DMIKKELIEIDFDVKNQNEYFEKMAKKLNELGYVKDTFLEAILKREEKFPTALPYIVAIPHVEP---EHVKKPFIAASRLKNTIEWREMAALNTRFVFMLGFLETDHVNLLQVLIENFQNEELMDKLIEAKDKEKFLELLRAI- +> +-MLLRKDLIRIGLKGSTSEEVERNFAAVFVEAGVGKSNYPDAIVAREKDYPTALPFDIAIPHTYA---EYVNEEAMGIAILEHPVEFKQMGSLYPQLLFMLAIIDKNQLKTLQNIVKIVQSDDLLFRVKNAKTADEVYDILEPA- +> +-IVVTEKSILRNKEFDRREELLKELSSLLLNQEFVKGNFYEELVKRENEFPTGLNFGVAIPHTDP---GVVIKDSIAVAVLENPVQFGEMTNVNAKVVFLLALTDTKHLKVLQKIIKIIQDSNLLKSLFIK-DEYEMSNFLNSY- +> +-SLFRKDTIFFDDKEYTDKEVLHIIGKKLLDRGYVKESFGEALLEREANYPTGLAYPVAIPHTDP---GHVNEPCISIVRIKQGAVFHEMVNVKVNFVFCIALQVDKQTGVLQYLMQVAGDDSIMNIIKNAKNADEIYKVVSIK- +> +-EYVKEELILLNLDISNRNDLFRQLSEIFQERGYINEGFYDFIVEREENYPTGLDHTVAIPHGNP---EYIKQSFISVVTLQQPIKMKKMEDIDVAVFFVLGLSDTQHLQILKQVIGVIQQETFVNRIKAAKTSEEVMKEISAI- +> +-DLIDKRSVFANLEVDSSDQVIDVLSKSLFDQNRVISSFGDAVKAREIEYPTGIPITVAIPHTDV---KYVKQASLAFATLKKPVAFRNMGDLDVQIVVMLAMVEHSQVTVLQSLMSLFQEQDYLKELLTLDKQEDLYEHISKY- +> +-LVFDENLISTQLEASDNYDAMEKLGNILYTKGYVKDTFIDAVIEREKEYPTGIQFNIAIPHVDN---CHVKKPGIAIGVLKENVLFSRMDDLDVKVIFLLAIKTEYHLEALKEIMNLVQNAKAMNEICQCKNSKEIIKIIKRE- +> +-ALFTPELVFFDWECATPDEVFARLEGELAPHGYIASGWLDAVRTREDAYPTGLAANIAIPHTDP---GFVAKPYIAVVKSAAPVTFNAMAGVPAQIVINLGIAEGGQVEALQALMNIFMGADAAADVLGQTTPQGMVDAIRRH- +> +-NISKS-NVLLKHNCDTRAEVIALLADSLFASGKVKASFKQAVLEREESFATGLEICVAIPHTDR---EHVISDSIAVMTLNSPVGFNAMGTVSVRIVFMLAISSDKQIDTLQEVIDVVQDQELLSKLLCASDYQEFVDYLNVI- +> +-MFFNKEIIKFNFEGHSKEQVLSHLSEKFIENDLVTQDFYESIISRELSFPTGLWTGIAIPHTDS---EKVKQAQIGFMSLKQPVTFKEMANIEVSLIFMLALKQDQQLSMLQKLVNLFQNESLVKQLKECTSLIEFKSIMKNA- +> +-VSFDSDFARCDLDVATQEEIFEELARPLVAAGRVKGDYASFVQSRELRFPTGLPMGMAIPHTDP---EHVIAPAISVATLCNPVEFHVMGSVSVSVVFMLALDDHAHIAFLQRVVRFAQDKALMSQLINATTDDDLYQLVTGS- +> +-KGFHEGMIMISTQGKSKQEVLTELADHLQATGYVKESYADGILKREEIYPTGLSINVAVPHTDC---AHVNQDAIAVGLLDDPVIFQAMDDVPVSIIIMLALKEHGQIDMLQKVIALVKQQNDLKRMLTSVDTKDAYQVIAHY- +> +-SQLLNEKLMVPLRADGREEAFAQLAQGLQHYGYVKDSYFKALLNRESTFPTGLCINVALPHTDV---EHVLQPAIAVGVLEKPVRVASMDNIDVSIIFMLALKNHDQPKFLEKLVVLFGNKVLLRSLSAAKDVKTAYRLLLAA- +> +-ILIDPEYVFTELDAETRQDVFEELGGALLADGRVKDDYIAALAEREEGCPTGLPGGVAIPHTDA---SHVNQDTIVIATLAKPVAFREMGGVEVSTVFMLALASGEHLEVLQKIVKSIQRPEFLETIRSTTDPQVIADTASEA- +> +-QFLSSEHIIVTEEVVGREQILTQLGGRLVQSGAVADEYVPTILEREQQFPTGIEIHIAIPHADA---AYVRKPAVAMAVVKKGVSFRSMADLPVKIVIMLALEKETQLRVLEQIMSFIQHADRLQELVEMESGEAVFRALKQS- +> +-ILIDEKYIHIDCEYDNKEDLLKYLTDTMLEDNVIKNTFYENILAREFKYPTGLNIKVAIPHTNP---EHVNEAAISIATLKNPIKFNNMENLFVDLVFMLAVDNEKQVPLLVKLMGIFSQSDKLKEIKESKDKSEIKKIMEDL- +> +-DLLHEELVFLDVDARKTEDLFLFVGEELEKRGYVKSTFTRAIIEREALYPTGLAINIGIPHTDP---MHVNTGFVAVVKNKYKLPFIHMGTILIDYFFILGIKDADQVKLLQLLMEKFSNVEFIQGLQSNHEQHTLFSFIKNK- +> +-RYCNQDL-ILFSTLSVKEDILSYMAACLWRHGYTKESYREAVLARERVYPTGLGIGIAIPHTDI---VHVIKPAICLCILKDPVQFGLMGGVRVSVVFMLALREEKQLEVLQMVITMLEQEHYLKSLLQCCSTEEALSVLVQA- +> +-MTDAPRFLVLDADTANQEDLYSVVNSHLLSQEAVHETFLEAVSARELKYPTGLDCQVAIPHIDP---EHIITPGVLVCRNAQPTPFHAMDDLDVRLTIWPLVTDQNQTGMLGAVIALLQEETSYQRLLTESPEK-LEELLAGV- +> +-FSFDKRTVKARVKTNSHEEILRQLATMLYQAGYVAESFIDAIISREAIFPTGLPYGVAIPHTDP---HHVKEAMIAIATLEKPVNFKIMGNIEVTIVFMLAMRDSSQLQLLSNLMSVIQDIGLLKRIYASESEEELLAILNDA- +> +-LSFDSSLVVIDEEGLSCEDVERRLAGVLEEQGYVKDTYAQAIVDREANFPTALDLNVAIPHCDV---VNVNKAAMCMGVLANPVDWHKMDECKVSVVCMLALTEHAHLEMLQKVIAFVQDQELVGKVIAAQDADEVFSLAGSL- +> +-KLVSESDIFIDQEFQDEQEYFEVVTQHLLKEGKVKASFLESILQRERSYPTGLDIKVAIPHTDY---TNANTTQLVVTTFKSPVGFHQMDDIPVNVAIMILFNNEKQPQMLKYIMGIVQSQENLHEIINTKDVKSMKQLFENF- +> +-IHIDDDLIEMDLKVDSKKEVIKKLNKKMLKKEIVKESYLDAVLKREEEFPTALSINFAIPHTDP---KHVNRAALAIALLKNKVNFISMENIEVEIVFLLAIKDSKQVKVLQKLMEIMQSKVIVDKILTAENQSKLVDIFEKR- +> +-IIINEDLVQTDVIASTQNEIFEQLAKPLYDLNLVNEGFLEGVRRREQNFPTGLPFGVAIPHTDP---EYVKQNAISVGVLRHPVTFTVMGTTDVRVVFLLALNEQKQLNILKSITELIRDAKQLEKLLSCDSTEIYKILDSKL- +> +-AFLNPEAIELQSNAKSNVEIIRILAGKLERLGYVKPSYADAVVARELSLPTGLPDNVAVPHTDP---EHVIRTGIAFATLTSPIPFGNMEFLPVGFVFLLAIDDNTQIETLQQIMTTIQNADAMERLKQARTLADVEAALA--- +> +-EMFSEDNIYLGVDGNNFFEVLNNVSKELDKKKYINDGYIESVIEREKIFPTGLEYCIAIPHTDS---KYIKKDAIAIVKPKQSVIFRDMATLEVNIFLLLLISKENQVKVLSSVIKNFSDEDFYNKIIQNNDKKKILNIIKNK- +> +-RYLDRRAVLVGMPAADHGEAIDHLAARLQEIGRVHPSWGPAARTREETMPTGLPLNAAIPHTDP---EHVVEAAVGLAILPEPVRFQSMDDLDVRIVFALAIKDAEQIPLLQAVIEALSDEKRLARLAAARNPDEAFTALES-- +> +-FLDNRCIELK---YDSYEDLITNVSRELLKYGYVKESFLENILGREKQYPTGFEYNIAIPHTDM---ENVLKPVIYIVVLDRPVMFKSAEDISVDIVFVISLNEDKHIVVLEELMKIFSKNDLIEKIKNSEDKDELIRLIYEE- +> +-LLIRRELIRFHSRQTSVEGIFREAYETLLEKGYVRETYLEALLVREAAHPTALAINIAIPHADP---AHVKKGGIMAVALEKPVTFRHMMDVEVEYVFFLILTNSSHLDALSRLMSIMQKKEAVERIRGCETEDELYEVLAEL- +> +-NLFNKELVFLDIESPNANELFKIIADELQNKGFVNEKYHDGLINREKDFPTGLQYSVSIPHTDP---ETVKKDFIAIVRPRSPIMFSLMEDTPVDLCFFIGLRDKKSPLALMELISLIQNHKLILSILNEKNREKIIEKIQEV- +> +-ENFKSELVNLNLNVNNQKQFFQVISNDLKEKGYVVQTFKEAIIEREKMYPTGLQFAIAIPHTDV---VHIQHPFVAVYRLKKAINFYQMGTVPVKDVLVLGINEKKQVGLLSNLMQCFSKNEFVKKYKNITTSDSVIELIKNN- +> +-MQIDKELMMIGIDFQTKEDILESMGTRLHELGYVEDDFIENVLDREANFPTGLPYAVAIPHTDT---DKVIEPGIALATLKEPVPFSSMGNVGVKIVFMLAVDAGEQVTTLQNLIEMVQDEKVVSNLAAVRSIDECSKVLEDF- +> +-NLFKKELLVSSLNASTSEEVLRQLANVLTEHGYVKASFSDAIVAREGIFPTGLG--LAIPHTDR---EHTITDAIAVAVLSHPVEFVMMGSCLVSVVFMLAMSSDAQIETLQTIMGYAQSREALEALTRSAGVDEMYQVLSEG- +> +-TLVYSNLVNIENKSTSLIDFFESASRELVEENFVEESFFEAILSREQIYPTGLVINIAIPHTDV---DHIKKPFIYINKMEDDIEFTQMGSVIPEYVIILGIKEKKQVTLLSTLIELFNNSNFLDELQNCNNNDDLIKLFKNN- +> +-NFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGEKILARENVFPTGLNYGVAIPHTDA---EYIKEQFISVCTFNEPVVFSSMEDVPVNLAFVLGLNQHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL- +> +-LPIKLENIKLNQQYKNREDYLKKMGEQLLSAGLVNEGYSTSIINREEIYPTGLAINIAIPHTDY---QFSRTTDIFITVLKTPIAFFRMDEVEVSIIVQILFDNEKQPDILKELMEIITNQRVLKEMIAAQEPKEVLQHFQIN- +> +-NFINQELIFFNSQFISKEQFFKETTEKLKALEYVEDSFGSAITTRELNFPTGLQINIAIPHTDP---QHVKKPFIAAYQLKEPVEFVQMATVPCELILVLGITDKNQVGLLSTIMEVFGNVEKVSEYRKIKSPKELHKFLQEN- +> +-MFFNERIIELGMDAKSDTDVITQLARILTQKNIVKKSFTNHVLLREKKFPTGLPLGIAIPHTDS---IYVNKSQIAVASLKKPVVFKNMVDVEVSLVFMIAMSQHEQANLLSNLMNMCQHSQAVEDLIHANNENTVEKILRHY- +> +-KLFSKEVILFHQDIATQDEIFEKLNENLLAKGVVNDGFLAAIKKREKNFPTGLKFGVAIPHTDP---EFVNEDQIGFISLNKPIQFRQMGSVEAKMIFILCLKEHKQLDMLQNLMTLFGDDAKIEKLYACKSIEEFLNLIS--- +> +-EHLDDNIIFLNQSFYDRDEMFQFVSNELLKNGYVTGQYLEKVIYRENNHPTGFKINVAMPHVDS---EFVKKNGMFLITSKKGILFK--NEVLVQIVFGLLLKQDTHLNFLMKLASSFGNDQILQKIVESNSKVEIKNILKDI- +> +--MINEEFVYCNVDFSTSEEMLTTVSKDLFIAGFVTDMYGKKIIEREKKYPTGLKLNIAICHTDP---EYVLKNTLFFVRPKHAIKFK--NEIDVDLVIGLVFSSEEHLKILSFLAGLLSDSLCIHKIKESNTPKQLVMTMKEI- +> +-MYLDKELCLFQLEVKNQAELFKVMSEQLVTNGCVKDSFLEGIINREKEFPTALEIGFAIPHTDS---IHVNNSQICFASLKEPLVFYDMTNIPVSLVFMLAMSQHEQIDTLQNLVNLFQNQERVQELLSCTTKEQFIEIVHSA- +> +--MAIDVIVSGQDTITTYQEAIRTAGEKLVEKGNIDAKYIDACIEREIDFPTGLLDGIAIPHGNS---DLVNKDSISVVRIKNTVEFGRMEDVGCSLVFNLALASNQHIGILRKLIGLFQDEEFVDTCKNEETDT-VQKYLLTK- +> +-MYFDKRLCMFHQIFATQDELFETMFKTMFQAGVVKSDYLEGIKEREEEYPTGLLIGFAIPHTDS---SKVNYSQICFASLNQPVEFLNMGDIKVELVFMLAMSQHEQVQILQNLIALFQNKEAINVLKQCENEEEFMGILNRN- +> +-MFFNEKIAQFHILASSAEEVIEIAANELYQRGVVKKNFLENVLKRENEFPTGLNYCVAIPHTDS---DYANRSQIEFVSLKEPVYFKNMANIPVTLVFMIAMSAHEQAETLTKLMEMFSDQVLMKELDECDNIETFKNILQRK- +> +-MYFNSEIAEFQVEVRDRNEAFQRLTKELREKQFITDSFLQHIIEREERFPTGLPIGVAIPHTDS---EYVKKSQIAFMSLKEPITFFEMGTVDVQMIFMLALKEHEQLEMLQKLIGMIQQPEIMEKLYHCQTKSEFIEIIHHV- +> +-DYFKEENVFLKFEAENRDEFFSKIGEILLEKKYVKEDFVDSIKEREKNYPTGLNYNIAIPHTNP---EFVNEEGIVTVRLKNPVIFRDMGMLEVLLVFVLLIKKEEQVNTLMKLMSLLEKKDIYEKLIKAEEKDDILKILKKN- +> +-SLIQVDRIQVSCLVKDQFDAIALAAKPLLEKGCITEEFIDAAIERERIFPTGLPIGVALPHTEA---KYVLKESISILTLKNTIVFAGMGNIPVQIVFLLAISNEKQLRILQTIITIIQNEKMLKKIRDAKEPRDIYNLINTF- +> +--MFKEELIFLDHNFDSSDEVIKYSFKQLRRLDYVKEEYLDSILARESEFPTGLMINIAIPHTDS---DLAIKEAIVFIRNKKDVVFQHMIDVPTKLIFNIVVKDKNQVSFLTKLMKMFQNEILLEFLLTETDKEKIIQTLKNF- +> +-REIDKDLIFINMNFENKSELFGFIADELKKRNYVTDTYEEAVNKREEKFPTGFQINIAMPHADP---VNSRADKLVVLTLEKPVEFQ--NEIGVNIVFGLVFHNDKHIDYLMRLSNLIQDSGKLEKIKKSVTKDEIYDLLDET- +> +-MLFPECTLIH---ADRKEDVIWKLYEKLLQNGKVKENFYEAVLEREREYPTGLKWEVAIPHVSP---EYVLESTIAIAVLDEPVEFKRMDDVHVNVVFNIALGKGKQIEILQDIMAIFADSEKMERIVKAESPEQVISIIKG-- +> +-MLLEKDLIFTEQNFNNRMEIFKFLNENLINLGYVKDSFLKGLVDREKNYPTGLKCGIAIPHTDS---IHIKEEKLSILTLKNSVSFENMDGVDVKIVIMMLIKGNNQIEMLQKLFTLFTDSKKIEYLKNLVSEEEIIDFFNKE- +> +-MIIDDNLIFSNLECENSNEVLRFLSDNLEKNGYVKSSFYDGLLEREAAYPTGLDYSIAMPHTEV---EHVVKSTLSIATLKKKVDFKCAEDTPVEVVCVIAFGEEDKIDVLTKLISFFGDKEEFYKMLAS-DKDNLIKIVKKH- +> +--MIQKDLIYIHLKADTKEEIITRLADKLLEAGKVKDSFKTAVLKREVEYPTGLPYNMAMPHTFA---AHVIEPTIAVAKLDEPVLFTEMGTLPVSLVMMMAISDREQVGMLKKILRIFSEEAALEALMKSEDVDEMYKTLRYI- +> +--MIDKKYIVKNLEVNSQKELLERLGKQLVEDRIVKEGFTEALLEREREFPTGLPPGVAIPHTNG---SLVNEDRLLFATLKNPIKFNEMGAVDVQVVILLAIADQNHIQTLQKLIGSIQKEGFIKGLVDSKDTEEMESIIRQY- +> +-LNLYPEDILLRIDADSCEEVLHLASSHLLGEGKVKQSYEEHLLAREEDYPTGLAINVAIPHTDY---QYANTTQLLVATLAKPVMWHNMEDIPVSVVVLSVFDKEHQLEALQQIMGVLQKQELVAQIVDADSAQQVIELFN--- +> +--MLTQELIFLQREEKTSFEFLSNISDKLLSMGYIKESFKKAILKREEIFPTGIGYSIAIPHTDS---EHIIKPGIAFVRFNNKCAFKEMCTLDVTMAFVLLVKAEEQAVLLSKLMGLFTDNELLDKLNSENDCETIVNILNDK- +> +-SLLHTDLIILDAEVASAEEAIRLMGDRLEKLGFVTEGYADMVCDREKTYPTGLSWAIALPHTDP---TLVIRPAVGVIVPREPVEFKMMGALDVRLIMPLVIKDNSQLSLLKTMMGVIADAQLLERIRRSRDPREIIELLRP-- +> +-IFSKNDIHGLISEETDRDQLIHLLAAEMAKYGMVEPCYGASVLEREKEFPTGVPVPIAIPHSER---SQVYKPGIGVAVLRNSVKFSSMEDLDVRVVFMLAASLDEHLHMIKDVMEIIQDSEVVNALLAAETTKEIEAIMHQ-- +> +-LVFDQDLIQLHARYDSREELIKSFGKKIEEKNYAKKGYTESLLQREIEYPTGITIGIAIPHTNK---EFVNETAIAVAVLDNSIEFEDMGGVNAEIVMVLVVKNKMHISFLKNLTSLFQEEKFVKRFQNATNPAEIEEILLK-- +> +-FQFIPQLIETDVCVKDKEEVIRHLADKLKAHGCSDAAYADKVLLREQEYPTGLCAAIAIPHAFD---PAISGNHVALAILQHPIRFCNMEDIDVDMVFLMAISSHEQLGMLQTIMRMLGDDTLFTRLVRLHDADEVCRQLNA-- +> +-NLVERNCILLDQEIHSFEEVIQLIGKEFESAQIVKPSYVEAVIEREKVFPTGLGHTIAIPHTDP---EHVLRPGMGVVVTKEPIEVSMMGSLQSNIFFPLAMEHKKQLDLLRQLMSIFKTKEDLDTIRAAKTPDDVLAVTSK-- +> +-LLIDSQLIVREKNFPDCEAAIRYGGSILYRLGYVKDTYTDSVLAREKLFPTGLPVPIAIPHTGS---EHVNRSMFCMIVFDNPVMFRQMGSIPAEIMLLLAIDGERHLEFLSDILGIFSDGSVLTRIRAAGSAEEICSILGE-- +> +-TLFDSDLTFWGWSCTTPNELFARLADELEVRDLVAPTWRGAVATREEVYPTGLSCGIALPHADA---EHIIRPFIALVRPASPIPFEPMGGVDAELVMALGFTHEDQIGALQHVMEVFANERTGEALRAATSPAELIALLRG-- +> +-GTLTEDLALVHPEVTGTEDLLRLMAEQARRAGRVHDTFADAVVARERRFPTGL-VPAAIPHTDA---GHVAEAGVVVALLARPVEFTEMGSVPAELAVMLLVKDEEQVTALGEVIAVLQDPALAERLAGVRDPADLVAALRP-- +> +-MLLKEELVRVGLDAHDGEEALRKVAQGFVDAGYAKDSYPQAIVDREAVFPTALAFDIAIPHCDP---AHINEPAVSIVTLREPVELKMMGDLRPRVLFMLALE-HGQVEMLRRLMEVIQDQRLLEAIGACANAHELYVLMAE-- +> +-KMFFPELVDVYEGTGTFDALIDYTAKKLAELGFIETTYQEALKEREKEYPTGLQFAVAIPHTDP---SHIKKPFIYILKLGESVTFGQMGTVNARYAFFLGFNKEDQLQLLQNLMAMFMDQDIMRQLEEESSESEILKIVTQF- +> +-ELFNKDLILTNLHCSSKDDFFEKVSNYLMEKGYVKENFKKAIMEREQKYPTGLRFHVAIPHTDP---ENILTPFIMVVRPDQEIEFVEMGTVKARFIFVLGLNKEAQAPLLEKLIEMFMNSEAMNRIVNENDENKIMDILKKN- +> +-LFFKQDLIFRDVDWKDSTELFDKISTILEDKGYVYSTFHKAIKEREKIYPTGIQIGVAIPHTDP---KNIKQAFISMVRPKKPIGFSPMGGIQAKLIFVLGVKRGLQVKVLQKLMEIFSNGDIINIMLHAQSDRELYEIMKNS- +> +-DILREDLVDLSVEAASCTDLFMRISDVLFSKGYVVQEYGQQLQKREHAFPTGLAVDVAIPHTDA---VFVKEPFVYVLKPKTKIAFHQMGTVHPKLIFILGFSKDMQLALLQTLMKIFNDETMMDQLIEAETEKELFELLRKQ- +> +-ELFDESLIELNGNFSSQAAFFKAVSLKLQNLQYVKNGFFEKIQEREKKFPTGLKFNVAIPHTDP---EYVNRSFIYVIRMRNSLPFCQMGTVYPKLIFLLGVTKELQLSILQSLMKLFSHEEQMTNLLEFEEAKDFVQRIREF- +> +-DLFQKELTLINSSYESQAELFECTSNILEKEQYVEATFREAVTNREVIFPTGLEIKIAIPHTDT---IYVKRPFVLVNKLSTPIPFIQMGSIDVEVIFMLGIKNKDQVPLLSSIMEKFMEADFVEQIKEINDSSALCDFLKKQ- +> +-RLLKKEMMYPEIHFTSQEQLFEFVGNELGRAGYVTPTYKEKISEREKSFPTGLRVDVAIPHTDP---ETVKRAFIMVMKLTEGIPFNQMGTVYPKLVFVLGFDHDIQLELLQGLMTLFNNQLAMKKLLEATCAEQLLNILEQE- +> +-AIIDPSLIFTDINLTTQTDLFRFMADVLQQKKYIEKPFLKAVIQREAQFPTGMQCGVAIPHTDP---QFIKRSFIFFVRPQQPLLFHKMEDLNVSFVLLLGLDNGNHLKILQRLMTMFQKQTLIQQLLSSANNAAICDLLKNN- +> +-ELMQEELIDLSCGITSKRKFFKTKVEVLKGLKLVEETYLKSVIEREKEYPTGLKVSVAIPHTSI---NHIKKPFIYFNRLMKKIEFIQMGTVKPDYILMLGIKEREQVNLLAEIINLFNQKEFVTSIRNAKSKKEIMELFDVK- +> +-EMLKPDLVFLNVDEKDRKGLYKNIASKLLKLGYVKESYEEALNKREDEFPTGVVISIALPHANP---ENINKPFVCVVTTKTPIEILQMGYENADTFFFLGIQHNDQLTLLQKFMALIQNKDFVDDFQSISDESEMYQYIQNE- +> +-SLFDETLITLDASYSSQEDLFKNAAEHLVDLGYIEETYLEALVNREREFPTGLECNIAIPHTDA---PHIKHPFIYLIRLNENLKFKNMGDVAVKIVLFLGIKNKKQISLLSDLMGKFEDEDISKMILNGKNEKELEQNLKKL- +> +-SLFSEELITLDASYSSQEDLFRSAAKHLVDLGYIEETYLNALMTREKDFPTGLECNIAIPHTDA---PHIKHPFIYLVRLNENLQFKNMGDVAVKIVMFLGIKNKKQISLLSDLMEKFQEEKISRIILNGHDAKELETNLKEI- +> +--MFSSETIELDVMTASQDDLFRLIAEKLQGLGYVNSDYLEALTKRESVFPTGINCGLAIPHTES---DYIEKQGIAFVRLKETIRFKEMVSVDVKMLFFLLVKNAEQVKFLSDLMGKFSDDAFLTALLVGKDESAILETLNER- +> +-DLIQIKDVDVNVVANDKYDLFQKISQSVALKVNVSSIIYDLLKERELLGSTAIGNGFALPHLKL---KDVKS-YIGVFVLKAPIDFDSIDDITVSVIFVVLSPSSLQLKTLTFLAKILKKSNVEHFLN--KSPQEIKDYLKTL- +> +-RITFINTVKLNINCKEKFECLKKMAEYLAKENNLSEDVFSLLMAREKFGSTAVGGYFALPHAKM---DSLSKLICGIFTTEEPIDFGSLDGVPSQIFLVVLAPSSILLKALAKAAKIFKDNQLKERIISEKDKEKVIEFIKNK- +> +-DLLLENCFFTDVNVKDKWQFFKEISACIAKEVGLPEKIEEALVEREKLGTTAVGGGIAIPHSRV---EGLEKIVIAAAISRKGLDFEALDKKPVYLIFVVLAPESLYLKTLAQLARILKQEQVKKRLLEAKDIQEFKKVLAEI- +> +-RNLSKEVIFLDLMTKGKRSALSKIAVKIAQRGLDDRAVFRRLWKRESSGATGIGHGIAVPHAVF---QSISCPVASFTRLATPIHFGSPDGDPVDLVFTLLWPRATFLPALAQLCRVVRAPRIRKGLRLARSSDEVMAILDGD- +> +-EVLAEDGIDLNFVAKEKHSALAKLAAMLATQGIDDKIIRRELLARERLGATGVGWGIAIPHALM---DELTKPVACMARLKEPIDFSAIDDAPVDILFGLLWPRGTFLPALSYLARTFRNQTTRHLIRQATTPAAVLSCLDHC- +> +-DILTERDIVLDVLATDKAAVLARAAILLARTGADQQTIGEALVAREQTGSTGFGSGVAIPHALV---GGISAPTACLLLLGQPVAYDAIDERPVDIALGLLWPKRGFLPGLAQIARVMRSGRTRKLLRTAPTAAAALAYLDQK- +> +-SNLSEDNITLDLATKGKHSALSRIAVKLARGGLDDRAILRGIWRRERVGSTAIGRGIAVPHVLL---RSISSPVASFTRLAPPIDFNSPDSDPVDLVFTLLWPRRTFLPALSRLFRTVRAPLIREGLRLAQSPEEVMAILMSE- +> +-KNLSEKDVTLDLVTKGKLSALSKIAVRIARRGVDDQVVLRRLWKRESGGATGIGRGIAVPHALF---PSISCPVASFTRLAAPINFGSPDGDPVDLVFTLLWPRATFLPALAQLCRLVRAPQIHEGLRLARSSDEVMAILDND- +> +-DLLNEDLLIPRLAADSKISAINELVDALHRGGIVTLSFLQSVLERENLQSTILGGDVALPHARS---RAASRLGLALATMAQPIDFPSGDDCAVQLICLIAVPADLYLSLLASLAQTLSDANLKRGLLHAATAGDMHRLLTE-- +> +-GLLHPDLLVPGLEANGKIEVIKHLIDRLHEQGVIDLAFLQAVLERENLQSTVIDEMIALPHARG---RMVKRLGVAIGTRDCSIEFPSGDEHDVGIICLIAVPAGLYLKLIGVLARAFSDRAFVDTLIATQDAPQMHQLLTD-- +> +-PWIDPEMMVPSLVSDDRMGAIKELVDRLHVTDRVDLSFLQAVLGREDLQSTVVEAGVAFPHARS---RSVRRMGASIGLSRAGINFGTATHQDVHLVCLLAVPTENYLPFLAALSRSFAQPAIRSQLMSCSTPEAMFHHVTN-- +> +-IRIEAGLFLPALEVSSQEELFAALADALGAAGAIHNAFQRLLVEREALGTTGLGHGIAIPHARS---MVAQRTTLVVARLARGLDFQAVDGPVERVFLVVAPYGEGYLPLLGVLVAAVHHDTDRERLLAVESFDDLEKLARQ-- +> +-------LDVPKGEGTSFASLTRFVASHLEADGCVTSSWGGAVLAREQLYPTGLPPPVAIPHADT---THTLKDALVVARLAEPLAFGAMGDLQVRLAVFIVAGNMAQVEVLERLLSILGDGARRERLEAGSAE-HACRSFEE-- +> +-------NIFIQESFKEHESALIFLSEQLRRKGKVLDGFKEALLEREENYPTGLLDNVAIPHVDH---KYVKESEILLCTLENPIPFRRMDMVEVSIIILLAIDSDGHLEILRKIVKFVQNQEVLRKMFKEKDKDKVSEILDD-- +> +-------IYVIEGNPVSWKEAIQMTADELYKNGCVEADFYQNCIKREQMYPTGLAVPVAIPHAES---CCIHKNGICLLRLATPVSFHRMDNLPVDFVLNLAVMDAVQLRALQNTINLFQDKEFQSDIRKLKLQ-QLKKVFVD-- +> +-------YLAIEGEAKDWEEAISLCGQAIAKAGYADKTFMKACIEREKEYPTGLPVPVAIPHSKV---DGIKDNCVCFLRLKNPVRFYRMDSIETTAVFNLAIKDDQHLEFLQALMQAVMNKEVVENCMTKKLD-EIPEYLRE-- +> +-------FLVFNGSALDNNEAIDKCVEKLVENGITDNLFSKLCIEREKEYPTGLPIPVALPHAYY---ENINKNCICVMRLNSPVKFKRMDDVDAKIVFNLAIKDNKHIKTLQYLMGLFSDGDSLKKILAMNED-NLIKYLEE-- +> +-------FKAIELNERSNIEVIKQCGLELLNEGIVGNSFIESCIERENHFPTGLPPPVAIPHTFD---PSVKESSVCYARLKKPVTFKQMDTLAVEHVFCMALKDHTYIDFLQKLILNIQSQNFIVQLSKCEPE-NLVDFLRE-- +> +-------IFVMDGSADSWEDAIQICTERLIEEGVVKPSFKEACLKREQAFPTGLPPGVAIPHAGN---EHVYENGICLLRLKHPVLFQRLDVVPVNFVYNLATSEEGHIDILKKLMESIHSGQILKDYMDVPLE-QLYDMVYK-- +> +-------LVFLDKEYKDFEDVLSHVMKTLINENYAEKDFEEALLIREKEFPTGLQGAVAIPHGGS---QYVKQDFISMVTLKNPIFMNRMDNLAIDILFIIGFGKDTHLQCLKQLMGLIQDPKVIEDLRKGTSIMSVL------- +> +SSLLDPTRILLDVQSTKRTAALHEIAALLEPHPDVAPGFYQELLARERLDTTCLGNEIAIPHART---EHVKQIVIAVGRSTAGVHFEN-SNQNVRLLFILGTPKGDYLMLVGSLCRLVKDAPHRKALFAATTPAAFIATVQEL- +> +ADLLDEKQVILRLRSRKPANAIREIVQVLAHNGKIDETFLEQVFASERAHPSVVENGVAFPHART---DLVNQIVLGIGRSRAGIPFGQ-SGTRAHLIFVIGVPQNDYLICVGTLARLAKDEAIRSTLLHAETPREFLDALAVE- +> +SEILDPSLVVLELREGTAAEAILEIAELLRDHGRVQFKFADAVMEREGRTSTNTGEGVAFPHART---DLVDRLILGIGRTTPGIRFGP-TKELVHLIFLFGVPKTNYLVCVGGVARVVKDKTKRDALLAASTADEIVEQLRTG- +> +ADLLTEQQVILRLSSRKPANAIREIVNVLASGRKIAEVFLEQVLARERTHPSIVENGVVFPHART---DLVDEIVIGVGRSRAGIRFGE-NQHRANLIFVIGVPESDYLVCVGTIARLAKDDAIRSRLLNVETAREFVDALTAD- +> +SDFFKKDFCSLDLKAATKEGAIREIAALLSKSGKLKERFVSDLLGKWRHNPGCFDKKTAIAHSLS---ESVDGLVAGFGRSKNGIDFNAPDCEKANLVFLIGANPDIYLVMLAKLSKLLSEEFFRRELSSAVTHSEIISIIKRF- +> +ADLLRPDHIALQTRAKDPKSAIDEVAGLLKSVPAVLQALLKGVQSSAPCLPEGGGFALCIPHTRG---ECVNEMVMSVGRSEAGIVFPN-VELPVRYVFCIAVPRADYLRIVGLLARVFKDRTSEAELRAATTGTEFVDLLSRR- +> +LAPLTPERVVLPISSTRKVDAIREIACLFQSSGSVTRRFLSALLQQEQRFGSGVEKGVALSHYRD---ETIVDPVIGLGISKQGIDWGD--GSVVNILVLIGWPDKVYLQTVAQLASALHQNSIRSKVLEATDTDTIVKAIKSS- +> +TDVLTQDRVLFNLTANDRFEAITKVAQLLSNSPKIQAAFLDALLEAERAGLTWFEQEVAFPHIRS---ELVKELILAAGFFSPGVFFRE-NAPLVQLIFVIGAPKTTDIVVVGSLARIVSKNK--NRLLNAKNAQKFISLLSEY- +> +---------MLDLTASSREATLRALHARLCSTDAVSDRFLLDLLERAMVAPVCISADVATPHART---TAVERIVLGVARTAPGVGFDG-EHPAVRLIFMIGTPKTEYLELVATISRVLKVAGAREALLEAESEAKFRAALSRA- +> +--------------------LLSEIAKLAAGAPQLEETILTSLKEREKLVSTGLEKGIAIPHCSF---EGVEDFAVGLIVIPEGIEFEALDGKPSKLVFFIVGPSNRHIKILSSISQLAKDQGLNRRLVSAGTPDEIVGILEE-- +> +--------------------VLKIIAHIAKKNPILEKQIYKSLQEREELGSTGFSNQIAIPHCAL---EGISDFVLGILIVSEGVEFDSLDKQKTKIFVYIIAPASQHLRILSTISNYLRNQDNINKLLLAKSPSAIRETFLR-- +> +--------------------LLAEISSLAADMAGLRDRIAAVLKEREELATTALGSGTAIPHCRM---PGLNNFITGVVTTKKPIDYGAADGKKVDIFPFVIAPEKEHLKILSGMARILRNPDTRKAIRSINDSEELYNFLSD-- +> +--------------------ALEEVSRLACQVPELQEKILSALLTREETGSTGFQKGIAIPHCLI---EGISSFTVGLITIPGGMDFDSMDGLPTRVMAFIIGPTTDHIHILAGISRVLSTLENPDEIALCDSPMRVSEIMTS-- +> +--------------------VLHKIADMAASCPGLPDILYDKLSEREDLLSTGIGNGIALPHCTL---DDLEDFVIGILVVPSGVNFKAIDKKKVKLFIFIFAPKNDHISYLARISQILQSPENVEEIVSQTDPEKVYEIFSK-- +> +--------------------LLRKIAALSGNTEELEEEIYQKLKKREEQGSTAFGSGIAVPHCSF---KGLESFVLGLLILKKGTSFDAPDKKPVNLCFFIIGPENEHIQILSGITRLLNTTEAAKQLRQARWPDDAYSILVG-- +> +--------------------VMREVARLAKQCRVLEQEILVGLQAREAVGSTGVGKAVAIPHCRL---KSVKEFVVGLITVPSGVDFDSIDAEKVKLIVFIIAPENKHVRLLSVISQMLLAPKVPERILSEQTPEGVYETCVR-- +> +--------------------ALRIVARQAVQHPSLPDEIFEALQTREEIGTTGFGDGIALPHCRM---EGATEFVVGAISVTDGVEFDSLDGRPAKLLVFIIAPARAHVRLLSSISHTLLIPGAVDEMLACTTAKNLLDSFTR-- +> +--------------------VLENISDMVMKKIGTKHEVLRKLREREEIGTTGFGNHIAIPHCAL---SNIDDFVIGMLVYNDGADFDSMDEKPVKLAVFIIAPENQHIRFLSEVSGVLRQPGALEDISAQINSVAVRERFLK-- +> +--------------------VLKEITELAKENQQLADEIFKALEDREKAGTTGFGDGIAIPHCSF---EDIDHFVVGMMTFAGGVAFESVDRKPVFALFFIIGPSNRHIQILSSISKILLEKSTLASIRKAKSVEEIVEIIRG-- +> +--------------------VIREISEIAKASNLLVDDIYKAFMERENLGSTGFGDRIGIPHCRL---KNMESFVVGAVIDKEGVDFESMDGSKTNVFFFMIGPDSQHIKILSEISKILKEEGAVDKLLDSKTSSELYSNIVS-- +> +--------------------ILETIAEVAKRSPILQERILQALVARENVGSTGFEDGIAIPHCRM---AGLNHFVAGLITTPKGVAFDAMDDRPTHFFFFVIGPDNAYVRLLSNISRVAGRADIRKKLSASTSSMGAYAILID-- +> +---LRAGKVHRDVPSNGRESTIRAIVERTVLPALAPAFVVAVMVARERTLWTAIGNGIAIPQVRQPIIA-GLPVTVSVSYLEQPLLFGAPDGKPIQVIFQIISPTGEHLRVLAHLSRALLDPGFCAVIERRGSNEDLAMAAHPL- +> +---MKRGGVLHDLKGDDMETALKSAVDHMPVLSTSKKELYRLLLERERLTSTGIGKGVAIPHPRDPLSD-MNSPIISTCFLEKPIDFGAVDDRPVFVMFIFLSQSKFHLHLLSRFSFCVRDSSFVEFLKTSPDETTFFAKIADF- +> +---LARGCVIDGISGADPASLIQNAVDAIAASGHLSARLKELLLEREALTSTGIGNGIAIPHPRAPMET-FPTTRVATVFPSRPVDFNAVDRKPVFVFFFLLSPTRQHLQLLSSLSFCVRDASFVDFLRRRPDKENLMARIREA- +> +---LGTGGIIYRLDGRTRDEVLHSLVSHLHLPEVDRDYLRQVLIAREELASTAFGGGVALPHPRSPGLLNLNQPTLTLAFLEHPVDFGALDGRPVGILFLPLAPTRTHLHLLRQVAHALHNAEVREVLHRQGNREEIFAAMEHD- +> +---MRAGGVMRGICANTLPELLCPVVGHMIPDPHQRELVLAMLLAREATGITAVGGGVLAPHVRAPLIL-ETPRIV-LVYPARPLPVPTPDNAPIEAVFVLASPTRAHLTLLALLAAALRDADFRQAVLSRASEAALLTAAAAA- +> +---LKAGGVYYDVPGGSREEVLKNVIEFLPFPAMNKSSLLEMFLARESLESTAIGNGIALPHLRSPVVLNVDAPWVSLCFLKNAVDFKALDRKTVSVLFVLVSPSKAHLLILSRLSYCLQDSGFQKYLKTKASKEQMVAEAIVV- +> +---LKIGGVYYDVNGKNREEVLKNAVDLLPLPAVDKKLILEMFLARESMESTAVGNGIALPHLRNPVILNIDKPFVALCFLKSPVDFNAFDHQPVSVLFVLVSPSKTHLLLLSRLSFCLQDAGFQRRIRAQDSKEELTAEVIVI- +> +---VRAGGVHDDVPGTDKAAVLQAVVDQLPLPSVNRGFLYQMLMAREQLGSTGFGHGIAIPHARDPVVLRVAAPAVAVSYLATPVDFDSLDGKPVHTLFTMVSPSRVHLHLLAHLATALQDVDVLAAVTARAPEPELIEALARV- +> +---LRLGGIHYGLKGTDRESALRSIVSSLRIPNVDEEFLYQLLLSREGLGSTGVGYGIAIPHPRKPIVLGRSDSSVSLCFMEHPIDFGAADKKPVDIFFLIISNTREHLHLLSMISLAIHDDSFRKLLIDRASPELLFGDLERI- +> +---MRRGGVFFSVKGRDVREVLEAACMLIPLPRIDWETLLDRLLQREELASTGIGNGIAFPHPRYPMED-PAGGMISTCFLENEVDFNAVDGSPVFILFVILCPDKTHLKLLSRLSFCLRDRGFIRFLRECGNGDDLLIRVRTM- +> +---IECGGVYWDVPGSTPSEVLEAIVDRVPMRPVPRDDLLALLRSREGVGSTSLGSGFAVPHPRYPLVH-TVPPTLAVCHLAAPIAWDPNNADMVQTVFTLIAPTRIHLRLLAKLMYALSDSAFRNVIARKASAEETITAATAI- +> +---LKNGGIYFDIPGNNVVSVLESCVKKIFQVPDFKPDLLDRLVERENAFSTGVGNGMAIPHPRQQLSY-LPDPMITVNFLADPVDYNALDGRPVSILFCILCPSQHHLHLLSVLSFCLKDADFVAFIKSRPQLDELVEQTMVL- +> +---FENGNVFHAVPSDSLETLFXEIPACMNLPGHIKDTLAEQLMQREILSPTGIGNGXAVPHPKKPLGX-LKKSMIGTFFLEKPLDFKAPDGLPVFVVFVLLSADFHHLHLLSQLARLLNNTDINDFLKNSPSLEILVEKFQKN- +> +---LLRGGVHTGVKGERRDEIFGEVLNALPLPAVDKLSLKAMLISREQVGTTGIGNGIAIPHVKHPVIF-GLDPIVGLFFLEKPVNFAAPDGERVHTLFVILSGSRGHLSLLSRLAFCLQDLSVKTALDRRASPEEILTAFQVA- +> +---MRRGGVFKDVDGGTVDEALTQAASLSPVTSDHLQAFTQQLLERERLCSTGQGKGVAIPHVRSQTGD-GAEASITTCFLKEPLDFNAIDGKPVTTLFLLISPSDVHLRLLSRLAFCLRDDSFVEFLNQRPTPEDLLGKVQEL- +> +---LSRGGALEGDTGASRDELLERMVDQAPLERADRPALLLQLLEREGLTSTGLGDGIAMPHPRTPSAS-SAEPLVMLAQPEPALDWGALDGQAVHAVFLLVNPAPVHLKVLSRLAFVLRDAGFQALLRERASFEEILTRVAQL- +> +---LRKGGIHYKVAGSTVEEILKNAVALINAPPLDKETIVWHLLKREAMMTTALGSGIAIPHPRTPLIS-ISCESVSMCFLNGPVDFKALDNMPVSVLFIVLSANPRHLQILSQISHLCRKDGFMELIKRQALREEIFDYAGKE- +> +---FSDGRVFYDVDKTSKEDIFSFVVEKMDFSSKHKAEFLKRLFEREEMSSTGIGRGIAIPHPREPMEG-VEHSIINTVFLKEPVDFESIDNQKVFVLFVIVCRNKEHLKLLSSLSYCLRHDSFIDFLRKKPDPLEIFMEIDSF- +> +---ISAGGLMRGVEGETPAGVLKNLVEGAPLAKVDRSLLLERLLEREKMTSTGMGHGIALPHPRTPSQD-AMVPTVVIGLLQQPVDWMALDGERVHTALLLLSPNKSHLQLLSRVAFILRDSSFCKALAAKEEDHSLLVRLAEL- +> +---VRMGGIHFDIPGGEVKTVLESSIGRISNIPDFRDDLLERVMERENALSTGIGNGIAIPHPREPLTY-LNQALVSICFLSTPVEYNALDRRPVSVLFFILCPSKLHLNLLSTLSFCLKNTQFIGFLKSKPEPDLLIRQIETL- +> +---LVRGGVFYRIGGTTKKEVLQNALNMVKGVDSVSAPLFQMFLAREELASTGIGDHIAIPHARGSLVG-VSHPILALSFLESPIDYGALDGKPVYALFLLISPNRTHLRILAKLSFCLQAPEFKEAVLRQSSREQLLTTLSKT- +> +---LHAGGVFYQLHASVRESAWRALLGTLKLPA-DPDFLVRVLAAQERLLSTVFGEGIAMPHVRTPLVLRVPAPMLALGFFERPLEWGA--GPPVHVLFLAICRTSEHWHVLSRLSFALRDAQFKETIIKHSECDLIFSEARRV- +> +---LELGGTHYGLVGEDRDDVLRQLPEQLKLNKISPKKLGTLLLERENQSSTALGKGVAVPHPRYPLPI-KSQSRVDVFFLPTAVEWDAPDGQPVKILFLLLSAESHHLKILSQIAGLLRQAGVEDFLHQAPAQDELLDYIQTK- +> +---IARGDLVDDLPGCDRIEALSNLLSLIELPEVTRDELLDMLLAREKLASTAAGEGVAIPHPRKPLAD-IDEPHVWVARPRDPIDWGSIDQKPVRLVLLVLSCSKGHLDMLSRIALVMRAPEVRKALEQEPDRDKLCEIIEAH- +> +---ILRGAVGSAQPTD-AAKAIGFVNQLKDLPEEARLEIIDAVMERERMASTGLGRGVALPHPRRPVER-IKEPRLSVLFLEESLDWAAIDGQPVSTVLLLLSPSPMHLELLARVSLALHDSTLVELLRSAPDAAALLERVRVI- +> +---LLEGNIHYGVPGSDKKAVMAAVADRLPLASRDKALAAQALWDREMKGSTVI-DGIAIPHARSPLIF-VDRPIVTLCFLKEAVSFKAADVAPVNIVWTLVSPTRAHLAILAKVAAALHDAELRGLLSKPAPAPDILARLRTI- +> +-DLIEKGGVFYGVPGAAAADVYAFVCAHADFAEISADVFCRELISRDALMSTAVGNGIALPHPTHPLLKDASLQRIFLCFPERPLDMNAPDGRPVSSLFILLTGGRCHLDILSQLANLFQKTSVRHLLERQADKNTLLAEMRKI- +> +-TLLRRGGVWYNIPGKTSADFISTLVATIKLAGIDRDDLAQASARREASSSTAMGRALAFPHPGNPMAKSADDAIVALAYPRFPVDWKAPDGAPVKAVFMIVSASPDHLATLSILAKLCGDDAFYAALLRQAPLEELVGIIGKA- +> +-GLLTKGGVYYNVSGITPAEALGDMVATVSVRSIERERLLTAVLEREALMPTAAGHGIALPHPRNPLISEPSEQFVSVGFLQNPIDWQALDGKPVRTIILIVSASKLHLRTLSRLSFLCQQTSFRKLLADRSSREELMAALEEA- +> +-GMVRSGGVYYHITGATAEEVFTDAVSRISLAGVSPDALLTGLMERERLMSTSIGYGVALPHPRVPLVSGTENERIYVCYLDRGVNFDAMDGMPVHVLFLILSSGESHLGILSGLSYLLQQQPFRDALRSKPDTDELTAIMENH- +> +-ELCEKCETWFIADPQNMSKVITALVFAAPISSINHKVLIDALLSREEMMSTAIGNGIAIPHVRLFDSTNLKEDIVVVAYLFEPVDWKAPDGKPVHTLFFVLAADTRHLQILAEIAQLASDEDFVDFLKTMPSREALIERIRQI- +> +-ILFERGEVLEDVPGNSCAKIFEYICDRIVVSGLTAHQLQKELVEREKVLSTAVGNGIAIPHPRYPLVKNSSESKIVVAYLREPMDMQAPDVRKVYVMFVILSDSQFHIKVLSALATLFKNEKFRKGIQACPSKGELLDLLRRI- +> +-NLIKKGGIFYNVMGNNPKELITNSINLINTSNLSKEEIIYSLLQREDLMSTGIGKGIAIPHSRNPIIADIENECVALCFSENPIDYDAIDKIPVHSLFFVLSANKRHLEILSKIVFLCQQEQFVFILDKKPTKESILDFIEKK- +> +-EYLRAGGVYRDIEGDSPFEVFKSLSEKVNLSEILPVNLYEGLCAREAVLSTAVGNGIAIPHSQQPLLKNPKDQRIFICYLKNPIDMNAMDNKKVQTLIIPLSSSQSHLQIISLLAQLLSKSDFKKALELKLGLNEIYPLIRRI- +> +-ILIKKGGVFYGVEGTSPDKIFKAVTEQMDLVKSDADVIYNALCAREAIMTTAVGNGIALPHARTPVIKNEEDQRVCVVYLKEPIDMKAPDNIKVFVMFIILTQNQTHLQTLSSLVSLFKNAEFRKLLESHASEEDLLRAIERM- +> +-NILSPDRIVF-INHTTKRDALVELANNLSTAPQVKDELVTEILKREELMSTAIGRGIAIPHVRL---SSVTDLVMSVGICKKDIDYQSIDEIPVRILIMIAAAYTYYLQTLSFFSSKLKEKALRDKLLDASTPEEAYALLTQ-- +> +-NILSPDRVVS-LDYSTKRDVLIKMSDVLGTAPQIKSELTDEIIKREELMSTAIGCGIAIPHVRL---TSVTDLVMAVGISQKDIDFEPIDSEPVRLIFMIAAATAYYLQTLSFFSTKLKNAELRNKLLAAESPEIAYKVLTK-- +> +-DILTPENILL-SDFRSKTAVLNSLISVLSETHSIEEIFSMRILEREQMLSTAIGLGIAVPHVHL---SCVNNIVMACAVNRFPIDYNCIDGEPVRIVLMIASGFRRYLSLLSSCIGMLKERNFQDLLFNASSREQVWSLLAG-- +> +-NVLSPDRVVF-LDYSRKRDALVALAERLASAPQIKHELSAEILRREDLMSTAIGRGIAIPHVRL---SSVTDLVVAVGVSRCDIDFNPFDDQPVKLLFMIAAAYAYYLQTLSYFSAKLKSNELRSGILTCADPAAAYELLIA-- +> +-NILSPERIVF-MNHQTKHDSLVRLAQNLATAPQVKKELEAEILKREDLMSTSIGRGLAIPHVRL---SSVTDLVMSVGISKCDIGFQPVDEIPVRILFMIAAAYSYYLKTLSFFSAKLKDASLREVLLNSESPMDAYNLLIK-- +> +-DVLIPSRIVH-IDSENKRDALEEVSACLGHAPEITDELAKEIFIREELMSTGIGFNVAVPHVRL---NTITNIVMAVGISRNPIDYESLDEQPVRIICMLAARQAQYLKTLGLISNVLKNTTVRESLIETQDANSAYLVLTQ-- +> +-SVMTAERVLL-LPEGNKAGVLGQLIDSLSRAPEVRAVLRNGMLERERLMSTGIGFGVGVPHVRS---DAVSDLIMAVAVCKKGIDYDSLDGAPVKIVCMLAARATEYLRMLSSISSRLKDAPVREELLSLKDPAAVITLLMD-- \ No newline at end of file diff --git a/esm/source/examples/data/1xcr_1_A.a3m b/esm/source/examples/data/1xcr_1_A.a3m new file mode 100644 index 0000000000000000000000000000000000000000..4c0e1c0ee03d21cc210b1ba35cb1ad40ce919a19 --- /dev/null +++ b/esm/source/examples/data/1xcr_1_A.a3m @@ -0,0 +1,1176 @@ +> +CAEFSFHVPSLEELAGVMQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNQKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPVIQTESEHKPPVNGSYFAHVNPADGGCLLEKYSEKCHDFQCALLANLFASEGQPGKVIEVKAKRRTGPLNFVTCMRETLEKHYGNKPIGMGGTFIIQKGKVKSHIMPAEFSSCPLNSDEEVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHFFSRHGEGGHYHYDTTPDIVEYLGYFLPAEFLYRIDQPKETHSIGRD +> +--QQELATPDLEDVKKVLLKKLKSSFVEASVEVVDCPDLSVEPFNLAAKGLGGVTAVIEVGGPPYLLPNVDRQKVYNIKELASKV-LDPCFALGAGAAPWPFLGKNAEMMANVLIKVV----KNKTHVALVKDDGNDCEVRVLPDS--ETRFALMANLFFCEGVQSKVLKVHCKNRIGSENFVTCMRTALESEF-NSVLGLGGAFLIKNGKARQHVMP-DFSNSPIHSEEELNKWLNFYQMSAPLVAVGTFVSKDIELDLRVQHFHSFSNHNEGGHYHEDSTPTEVEYLGYFNLGQKIYRFDQPVNTHKFGRD +> +-------------MVNILQTGLKICFETAEVNVVDCPDLTQQPFHLAAPGLCGSPRLTDVGGVPYLVPLAQKEKKYNLDTVAEQV-LPGAFILGAGAGPHAAVGTNNEMIANIRTRD--SEGDNQTRLSSILPE-DGSYCLKC-SP--TRDFNLLANLMASEGKPGKVLEVKCQTRRSPDNFVSLMRHFIHKHYGDKFIGLGGVFVIEEGKAKIHIMP-DFSKKPLDTEEDVNKWLKFFEFKAPLICCSVFVTHDPGMDLRLEHTHCFSHHGQGGHYHHDVTPKTVSYRGYFVPAEWMYRIDPPTITHNIGRD +> +--SVKLDCPKLEDVANALQKGLPQYFAETEVAVVDCPDLREEPFNLAAKGLGGKTVVIDIGGPGFLFPLHDETKIYDMKDIANTV-MKSCFIIGAGAGPWPYIGKNCEMMANILINTS--SIVQKTYIAKVN-DKEDIEVELLPNS--EMRFSLLANLFACEGTSSKVLKVFCKKRKQDENFITSISTTLEKAF-NKTLGLGGTFLLKEGKARQHCMP-EFSKVPIRSNDDLNNWLKFYEMSAPLVAVGTLLSKDIDLHVRVQHFHSFSNHGEGGHYHYDTTPETVEYLGYFNLGQTLCRIDQPEKKQYFDKN +> +--KHALDPPPLVELASVISKGLQANYKSSTVSIIPCPDLTASPFHLAAPGLSGHESIADIGGPPFLHPLPDFSKKYSLPDILSHC---KGFAIGAGAGPFHVVGQNSELAPNISVDGE---VNNLTKYAKIGK-N-EVISGPV--PEGSTDCCLMANLFISSGLPGNVLKITAKSELA-NISVDGDGEVNNAKIG-NGEVISGPV--PEGSTDCCLMANGLPGNVL-KITAKKTWSN----G----------CDSST-GLRMEHTHCFAGDGKGGHYHGDTEDTEVEYEGYFNIARIIYRIDRPGGGHE---- +> +--IYPLAPPSLEELAEVLKAPLAANYERSNVAIVQCPNLQEAPFYLASQGLSGNEKIADVGGQPNLFPRPLLGTKWNMKDIATAM----SSLIGAGAGPYHQIGQNCELVPNFSWQLE--KANNQTRFVEISPQSKAARVR----KSPSLDCALMVNLYGSSGETGPVLKITAGRRKGHKSFTGCIQKALHAQYGSQTISLGGAFLVKSGKARYHVMP-DFPSDPFKNREEVDQWLTYHDFEGPMLCLSVMHSADPENGLRIEHTHSYSLGEDGGHYHYDIEESPIEYEGYFNTAKVLYRIERPM-------- +> +--SADLFAPALDDAVAPIAAFLRDRYEHASVEVVECPNLLS--WGLAMPGLGGQPRLVDVGGVPNLLDPAHQDKSFAIGDILDCA----PCVLGAASGDAAWAKGNTELMPCASRHC-------RSKSARVGADG-RCVLDEY--D--WDRVGFLANLFVCQGVPGPVLEVRARGRRLHDNFVGNIRGALLQRFP-RAIGLGGAFTMKKGLFKAHVMP-DFKDTVMVDGPEVQEWLKYYEMGPGATFLSTMLTQD-TPNLRLEHTHFFNQAGEGGHYHYGTSLD-VDYVGYFALAERVYRMENAFDRRRCNIP +> +--KMLLHQPPLEEVSEVLRTGLAKNFSFAEVNVVDCPDLSKDPFHLADKGISGQPRIVDLGGPDYLKPFAQKKKNYDFKTVAELS-LPNCLMVGAGAGPNHKVGINCELICNVKVGA-----INKTRIAKIDET-TGSYVLEE-ET--SGEFSLMGNFLVSEGKQGKVLQIKAKNRIGIENFVSCIHKTLTAHYG-KAVGLGGTFLLQTGKANIHVMP-DFLDEPLITDEQTNAWLKFFEMDAPLIHVGEIVSADPKLHLRQEHFHCFSHHGQGGHYHYDTTPDDAAYLAYFSVAEFVYRIDLPETRNFIF-- +> +----------------------LLACENLFAHRGLFPDLSVEPFSMTSTGFGRKMVIAEVGGPGNLFPIIHKEKEFDLK-ICNSC----PFVFGPGAGPWQVVGRNCEMVADANFTKV-------TKIASIPSSG-PYKMSVI--D--APKFSLMANLAVSAEPGADVVHVKCSVRTG-DNFPETMRKGLAEQFG-KCVSVAGIFIMQKGEAKLHVMP-DFPCCPFKSTVEIDQWLRFFTMKAPLVCASVFHSYD-GHKLRMEHTHCYSSHGDAGHYHYDTTPDVVEYEGWFTAAEKIYRFDEI--------- +> +LENCQLHVPPLSELADVLRQGLESHFAHVQVEVVDCPDLSSSPFHLAAPGLGGEPCLVDLGGVPYLVPTVQRDRTYDLADLPGLMNVKDGLMIGAGAGPWQHLNTNCEMMTNLSLTLEEGNIVNGTRLATVDPAGQ---RMLHVVPPEQTRCSLLNNLLISRGQPSPVLRIRCQKRTGPNNFVTCMRNTVAQHYGDKPVGIGGVFMLDNGQARLHIMP-DFSPCPLQTDADVNNWLHFYNATGPLINLSVFISHDPVLFYFMCFFHCSMTRYIALLIKSSINPQIQVLGAY-----SCWTMARPGSIYS---- +> +CSEFSFHVPSLEELAGVLQKGLQDNFAEVQVSVVDCPDLTKEPFTFPVNGICGKTR----------LPLVNQKKVYDLNKIAKEIKLPGA----AGAGPFQTLGFNSEFMPVIQTESEH---VNGSYFARV----------KYSEKYHDFGCALLANLFASEGQAGKVIEVKAKRRTGQLNFVTCMRQTLEKHYGDKPVGMGGTFVIQKGKVKSHIMPAEFSSCPLNSDEEMNKWLHFYEMKAPLVCLPVFVSRDPTLPPVPTDY-LF--PGRGQNLKEELSSKPTVAQAYN-----LGTL------------ +> +VAYKPLHVPPMEEIVKVLSNGLTTNFATVEVSVVDCPDLSKEPFTLACKGLGGKPRLIEVGGPPYLLPLVQRDKLYDMKDLGKLA--EV----GAGAGPWPYAGVNCEMMVNLEVNGG--KINNHTRISKVNMKDDSCILER----DSETRCALLANIFCSEGKPGKVIKVVCKKRIGSDDFIASIRKTLNSHYKDKAVGLGGTFLLKEGKAKQHIMP-DFSKTPINSDAEVDEWLHFYNMSAPLIAVGTLASSDPGLDLRLQHFHSFSHHGEGGHYHIDTEPEIVEYVGYFNVGEFVYRVDQPQVTHKIGRD +> +FEEKPLHVPPLTELQSVIQGALGQNFATVEVSVGACPDLKLPPYGLVESGLGGRPTLLEAGGPPFLRPLVNREKLYNVHEITRKI-QGP----GAGAGPWPIRNSNCEGIYNLSVSEDD-ILTNGSYTATVRGDQEECVLEK----NEEPRCALMMNLFLSQGLPGDVLHIKAKCRTGEKNFIDAIRQGLEEHYGNRIIGLGGLFLVKTGLVHQHVMR-DFSKTPITTPEQVKQWLKFYEMPAQLNAVGTLVTKDYGLDLRLQHFHSFSFSNWGGHYHYDTTPDIVEYEAYLNVAERIVRVDKPPHLGDRPSG +> +CVEFSFHVPSLEELAGVMQMGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNQKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSE-----------------------------------------------------------VIEVKAKRRTGPLNFVTCMRQNLEKHYGNKPVGMGGTFIIQKGKVKSHIMPAEFSSCPLNSDEEVNKWLHFYEKAPLVCLPVFVSRDPGFDL-RLEHTHFFSHHGEGGHYHYDTTPDIVEYLGYFLPAEFLYRIDQPKETHSVGRD +> +FEEKPLHVPPLPELQNVIQGALRGNFAPSWRACV----LEKIPHTEP--------------------------------------------RCALLLNLFLSQGAPGQ-----------------------------------------------------------VLKISAKQRTGEQNFIECIRKGLEDHYGDRVVGLGGIFLIKKGAVHQHVM-RDFSSTPIHTDEEVNEWLKFYDMPAQLNAVGTLVTKEHDLDLRLQHFHSFSFSNWGGHYHYDTTPDIVEYEAYLNVAERVVRVDKPLSTHKVGRD +> +SDDISYKLIDPDKLAHVLEDGLKRTFVNVSVKWVECPDLTQEPFNLAAPGLCGKPALMEVGDLSYLNPNPRKDKIYHINPIL--RHCNNSFIFGTG----------------------------------------------------------------------------------------------------------------------------ISEHPND--------------------------GTLGENLRCKSTHCLSHHNAGNHYLVDDTEDRIEYLGYFSPAKNVYRIDESRFGLPNLQ- +> +-KKIPLSPPTLSELAEKLQGPLSANYAHSSVTVVPCPDLRESPFLLAHEGLSGDEKIADVGGQTHLYPRPRKDKTYQLDQIAQEMEMDPAMFIGACAGSYELVGQNCEMVINNGWRGSCMCTSDNGRYVKIDPETKAVVLENA---HSKAWFGLMGNVFASRGGQGDVLKITARKRIGEGSFTECIRNALHNVYGSQIVSLGGVFAIKSGKARYHIMP-DFPPEPFRNREQFNGWLTYHDFKAPMTCMTVLHSADPKLGLRMEHTHAFSTENAGGHYHYDVEDEEIEYEGCFNTAKVLYRIDQPEHSL----- +> +VASRTLHQPPLDELMNVLAEGLTANFTEATVEMADCPNFSGWPYNFYREGLCGNPILLEVGSPAYLLPTVQRDKFYDVKSLLRQINYNY----GAGAGPWPHTGCNCELIMKLNIVND--KVSPGYRLGMGVANNGECILQRI---EDETTFALLANLYVCEGKPGKVIKVRAKKRTGKLDFISCMQKALEKHYEDKLVGLGGMFEVRNGKVKQHIMP-DFSDTPLTNEAQLNNWLRFYDMETPLIAVGTFVSAETDLDLRVQHFHSAFDERLGGHYHIDTTPDTIEYEGYFNVASTLYRVDQPPNKMQFGKD +> +IDRRDLFVPPVDDVISVLNQGLGKYFKEVSVSFTECPNLTSHPFNLTSAGLSGSPS---YGGASFLEPIANKSKIYDLKDLVNVTQTK------AGAGSWRFAGTNCEERRQTMLFSATAKT-TLTKLAL-TVAG-LEQGYVVCPS--EKRFLLLFTFLKAWHVLLQVIKIKVQTRIGKEDFVTSVRNVLAAHYKDQPVGLGGVILIENAPAKHHVMP-DFSTTPLETKDQLNEWLVFKDLTPPLISVGTVISADVVSFDIKAKS------------------------------------------------ +> +CAEFSFHVPSLEELAGVMQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNQRKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSE-----------------------------------------------------------FMPVIQTESEHKPPVNGSDGGCLLEKYSEKRHDFECALLANLASEGQPGKPAEFSSCPLNSDEEVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFLPAEFLYRIDQPKESHSIGRD +> +CAEFSFHVPSLEELAGVMQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKFMPVIQTESEH------KPPVNGSYFAHVNPADKYSEKRHDFECALLANLFASEGQPGK-----------------------------------------------------------VIEVKAKRRTGPLNFVTSMRQTLEKHYGNKPVGMGGTFIIQKGKVKSHIMPAEFSSCPLNSDEEVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHFFSHHGEGGHYHYDTTPDIVEYLGYFLPAEFLYRIDQPKESHSIGRD +> +IIPIDLYVPEKTELAIVLQNELSTDFEEVTVEWVDCPDLTQEPFNLAAPGLCGDIALLDIGGISNLFPFPIKNRNIYFKNILQEL---QSLIIGGGLCTRK--HLLHELIMNASEGKV----NNKSCFAATSGILHFVLSKSLANT--NPYCNIYGNFFVSKGLREQVLKVHAKHRT--RDFIVALQHAIKRFSKSQLMGFGGTFIIKNGKTIHHVIQ-NDWKVPIKMKKRIHKCIKYWKIDSPVVAFATFVSAD-HKNIYLNRWHVHA-SNDGGGYYHETEPNNTEYLGYFSPATKLYRINPVPIFREMINF +> +TSKYTLTPPPLEDLATRLQSALAKNYGHSSVTVSQCPDLRLPPFHLATQGLSSNECIADVGGQANLFPKPRLECKYSLLKIAKAMEMGPESLVGAGAGPFHVVGQNCELAPTLSWKGSFENIENRTYVAKIAKDSGEAIVSKCP----STDCALMVNLFGSSGLPGPVLKITARGRQGSGSFPKCISTALHEAYGSQPTF-PLNHLEAETTWKT-GSP-TIPSP----------------------------------------------------------------------------------------- +> +TTTHPLSPPTLEEICSTIRPALRANYKESTIDIVTCPDLTAPPFHLASQGLSGNESIADIGGQAHLFPRPLKEKQYSLIDCAKSMGMSQQLLMGAGAAPWHVIGQNAELAPNVSWEGSMDEVRNQTFVTRVESQGGHVRCERLP----SMEFALMMNLYGCEGITGDVLRVTAKGRRGEGSFTECLRQALHAEYGERQFSAPMVCLSVLHSADP-EKL-GLRME----------------------------------------------------------------------------------------- +> +VDKRSLHRPSLEEVAKALSDGLQSNFEHVQVDVVDCPDLRQKPFMLASEGICGQPRLADIGGVPYLVPIVQTDKIYDLEKVMKQTDVPDGFAIGAGAGPYHTVGINCEMMLNMKC---GQNPENKSHYAKIGED-GSCVLGKLSGP--PCEFCLMGNFLISEGKQGKVIKVSAKKRTGQENFVTAMRNGLKAKYGTEPVGMGGAFLLAQGKAKLHIMP-KFSTAPLLTEAAMNQWLKFFEMSAPLVCLSTFVSHDPGWDLRIEHTHCFSDHKQGGHYHYDTTPDEVEYLGYFSVAEWLYRIDAPASTHKIGRD +> +IVRIKLNTPPLRCIVKAILPELLENFENASAEVVQCPDLTQPPFNLTSEGLNGDENVFDIGDITNLIPSIKREKLYDVKDLKQIT----DVIIGACAGPYPFFGVDGESVENVTVENG-----THVHMMKSEDVA-ECYHKSLPDD--ETRFSFMANFFTSNGFRGEVLKIVCEVRK-GLSFSTCIREALKKHFG-EIIAIGGVILIENGKVKVHVVKPSLAKKPLKSGKELNKLVHFIELSPPSVGVGCIVSHD-GLL-RLQHIHLYT-RDQGGHYHNDTEPNTIKYTGYFGVSKQFTKIDKSNEVCNNLL- +> +TVRIDLNVPTLDRIIEALLPELSNNFETVSVDAVQCPNLTCSPFNLAAEGLNGDEMVIDIGSPSFLLPLVNLNKVYDIRDFAKVT----DFVIGAGAGPWPHVGVNCEFIGNVRSVNN----NSSHLYKVDPQTG-SQVHHRLPQD--ETRFALLANFYTSRGMTGEVLKIVCETRN-GLDFVTSIRKSVGKILW-QTGRFGWSDFN---------------------------------------------------------------------------------------------------------- +> +PLMINIHKPSNEELRTVIQAALEGNFKTVVTDVRQCPDLSADPFHMTSTGFGRKLVIADVGGPGNLFPI---------------------------------VGRCCEMVADANVA---------TKIASIPPEH-PYKMSVI--D--SSKFSLMANLAISGEPGAEVIHVKCSVRTG-ENFPEAIRKGLAKHFG-KTVSIAGIFIMQKGEAKLHVMP-DFPCCPFKSEDEIDKWLQFFTMKAPLVCASAISSEW-TL------IATQTMETQASHYHYDTTPDIVEYEGWFTAAEKLYRIDEV--------- +> +IIEKSLHAPPLEEIVEVLSQKLPSNFEYVRVSAEESPDLTRSPYNLTSPGLCGDAKLVELGGPPYLVPTVRRDKLYSLTDLLRHLRRDPALLAGAGAGPWPYLGVNCEGIINVYVKD--SAVSQGSHVVSVSPVQSSFVQEKLPASE---RTALLGNYLLSNGEPGMVIKVVAKKRIGEKNFITAIREALKEHYGDKVVGLGGTFALLEGRAKHHVMP-DFSATPLCSDSDVDSWLHYFEHSAPLAHVGTLVTGDLGLDLRVQHFHGVSEHGQGGHYHYDTTPLAAHYEGYFTVAGSVIRVDAPENTHAIGRD +> +---------------TFLESGLEKNFESVLVSVVDCPDLTQKPFNLSAKGLCGSPRLADVGGPPYLLPLPQKDKLYNQAEIARQVELPGAFILGAGAGPWQVVGVNSELACTVQVAAENEPISINSHVTKVNPQNNLWVLEKL--N--STDFNLMGNFLCCEGKPGKVIEIKARKRTGDENFMSATRQALQQQYGPQPVALGGVFVIEKGKANLHVMP-DFPCAPLSSDEEVDEWLKFYEMNAPLVCVGELVSHDPGLDLRVEHFHCFSEHGEGGHYHYDTTPEEVSYLAYFNIADSIYRVDQPPVSW----- +> +-VKLGLYQPEANELQSVLEKGLKNSFEEASVQIIDCPNLEKEPFNLAAKGICGRPTLIDVGGVRNLQPVPMRNKVYNLDELTQMTHNPDAFLMGAGGGPFHVTRVNCEFMANIRTSV-TGHGRNLSYIARLDSET-EYKLLQIPE---NRECGLMLNALVCEGTKGKVMYVRAKKRTRDTNFITAMRETLKVAYGNKPIGLGGVFLLQKGNAKLHIMP-DFPIYPLIDEATVNSWLKFYDMHAPLVCLSTFVTHDPEMDLRIEHTHCYSNHGQGGHYHYDTTPDTVEYMGYFVPCSTLYRIDKPPVPT----- +> +----------------PLQNGLKDCYKEVKVSITNCPDLKEAPFKLNLSGLTGQNVLCDVGSMKYLLPVPDKSKRYSFDKVAELSKVVQGQLLGAGAGPFFTHNKSCEMAANVKFSG-SKVISNSTLHGVYNETP-----EVIRAT--DNNFALLAHLLSTEGLPGSVIEVDVSGRLKEGSTYVFLREALKAAFSPNPVALGGVFVLNDSKARFHVLC-GLPDDPVDTPEKVAAFVKHFEMEPPILGVGTLVSHDPNVDLKLEHFHCYNEQTLAGHFYWDTEPENAHYHFYLVVAKNLLRIDPK--------- +> +-----------------------------------------------DTGVCGKTRIAEVGGVPYLLPLINKKKXYYLNKIAKEIQLPGAFVLRAGAGPSQTLGFNSEFMPVVQTESEHKPPVNGSYFAPVNAAEGGCLLEKYSEKYHDLGCALLANLFASEGQPGKVIEVKAKRRTGKLNFVTCMRQTLEKHYGDKPVGMGGAFVIQKGKVKTHIMLAEFSSCPLDSDA----------------------------------------------------------------------------------- +> +FEQKELFVPDTQELKEVLTLGLKKNFEEVSVDFVECPDLSKEPFNLASSGLCGNPTIIEYGGAPFLLPLVQRDKLYDLDEICQKICISEYLAVGAGAGPYVLCNTNAEGIFNLKRNA-DGSIVSKSHLALVNAEK-NCERRSIPSS--ETRSALLGNVYLSEGKGGQ-------------------------------------------------------------------------------------------------------------------------------------------------- +> +VSYYGVHEVSMEEVAKILQNGLKDCFKEVRVNVANCPDLTKAPFRLSLAGLSGQNVVCDVGSMKYLLPVADKSKKYSFDKVAE---VIQGQLLGAGAGPFFTHNKNCEMAANVN-FS-DSKVISNSTLHGVYDET-TNKPEVIRAT--DNNFALLAHLLSTEGLQGS-------------------------------------------------------------------------------------------------------------------------------------------------- +> +--------------------------------------------------------------------------------------------------------------------------IIGKSMATDHAVCGSPASERA--S--NTLISSMGQLFITEAMPGKVIEIVAHRRIGEPSIFDLIQASLYNKFSELPMALGCVFYLQNSGALANVLC-EIPQEPYHTFPCLKKYQASFNIDGPVIGVGTVLSHDPKMGFSMASFHCWNSRLLTGHFENDVCPEKATYTVYLTPAKKLYRQDKPVH------- +> +--ETDLFVPEAKGLARTLQNGLRKHFAEATVEWVDCSDLTQEPFNLAAPAF-------------------------------------------------------------------------------LDEDTGMCALESITNS--NPDYYPYGNLFISEGQPGQVLKVQAKKRIN-MGFLSALQNALYYEYSRQLVGLGGTFVMKNGRAKHHVLP-YSWNARLKAAADIHNWLHYFVLDAPLIAVGTLVSSS---------------------------------------------------------- +> +FRRFRLHRPDLVAVADCLDRACRDAFEDASVELIDCPDLSEPPFCLASRGICGGPVLSIAGGVPYLLPTPQEQRRYDLRNLLKAT----PLIIGAGAASSTRFGRNAELVANLGCRVA------DGEDDGTENLA-NCRLS--RPD--FAEAGLMVDSLCSSGQTGPVFRLRASRWRPTGRLAELLQRALAKEFSKLPVGLGGVFRLSGAAARMHVMP-DFSPTPLTCSAEVNSWLRFFNMPPPIVCCGVLISHD-HSGLRLEHYHGWNPEQCGGHYHYDASPDTAEYLGYFSLATSLLRMDPPGGVDSLTGE +> +VTKHLRDPPPLDELAAVIEKALLSNFKTASAIVAECPDLKQQPFNLAASGLSGSPRIADIGGQQHLFPRPNLNAKYSLLSLAQDM----KFLLGAGAAPFQDIGQNAELAPNLSNAPSLLTFDNGTRVIKVQRDG-TPLCDR----TSSTNCALMANLFGSDGGTGPVLKINARARKG-ENFTDCIRYGLQKVYGK-PISLGGVFLLKSGKAKFHIMP-DFPPEPFRDRRQLEEWLSYHIFQAPVVCLTVMHSSDPD-GLRMEHTHCFG-TTKGGHYHYDIQDGEVECDPSYLLKNILKDV------------ +> +ISRRELTKISFENIIEAISPELSKIFELVSVEVIQCPNLTQPPFYLAAEGLSGNETAMQFGGLPYVMPFGKKEKLYDMKDIMKIT----DFVVGAGAGPWPYANICSEFIGNLRSVNN-----RSHIYTIDPKND-QLVHEELPQN--ETRFSHMAHFFTSNGFRGEVLKIVCEKRI-DVDFVTSIRLALKKYFG-ETVVLGGVILIENGKVKVHVC-PDYSKTPLDSEKKLKDWLKIYDLPTPLVCLGYVASHD-GLMMPLQHFHVFS-HGSGGHYMNDVEPATIKYTAYFNIAKNFIRVDQPEAPFSFENF +> +QKVTVQFPARAHARVAVLQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNKKKVYDLNKIAKEI----PFILGAGAGPFQSLGFNSE-------FMEHKPPVNGSYFACINPEDGGCLLEEK---YHDHGCALLANLFASEGQPGKVIEVKAKRRNG-LNFVTCMRQTLEKHYG-KPVGMGGTFVIQKGKVKTHVMPREFSPCPLNSDEDVNNWLHFYEMKAPLICLPVFVSKDP--DLRLEHTHCFS-HGEGGHYHHDTTPDIVEYLGYFSPAEFLYRIDQPKETHSFGRD +> +VKKHTLYTPSLEEVAKVLNDGLKGYFKKVDVAVTDCPDLRQKPFMLASEGICGRPRLSDVGGVPYLIPMARTEKIYSINDVMKCV-LPDGFVIGAGAGPHHIVGVNCEMMHNMKC---GPNAVSNTHYAK-IED-EKCALGTLPPE--KCEFCLMANLLVSEGKPGRVLRVSAKHRIGEDNFVNSMRKILNKKYGANPVGLGGVFVIQQGKAKLHVMP-HFSETPLVTNDDVNKWLKFFNMSAPLVCLSTFLSHDPGWDLRIEHTHCFSDHGEGGHYHYDVTPTEVEYLGYFNIAEFLYRIDAPTVTHSIGR- +> +VKKHFLAAPDLHDLATVLDAGLKTHFQDVTAVVAPCPDLRAPPFHLASRGLSGNQRIADVGGPPNLHPTPKFDRKYSLLDLMSLM-MSPAFVLGAGAGPFHVLGVNTELMPNLG----AGELVNLTHFAKVDETTGKCVCDKIPSN--STDCALMANLFGSDGSPGDVIKIVAKRRIGEANFLAAIQQTLRARYG-RQVSMGGVFLIKRGKASMHVMP-DFSKTPLDM-KDSHKWLRFYEMEAPMVCLTVFHSYDPGLALRMEHTHCFSDHGEGGHYHHDTTPDDVEYEAYLNTASVLYRIDQPEVGN----- +> +LFFVTI---LNFIIFLVLHEGLSGAFSHVDVQVVDCPDLRKKPYMLSSEGLCGNPRIADVGGVEYLMPLAKKDKVYDFKDITKKI-MPNAFIIGAGAGPRPHIGINCEMMANLKL---GEGESINTHIAKLDKD-GACELVHLKD---NTQFCILGNIFISEGKPGKVLKVVAKNRKGSENFVTTMRLALAKKF-EKPVGIGGVFVIQTGKAKLHIMP-DYSETPLKSTDDVNNWLKFFNMPAPLSCLSVFVSSDPGLNLRVEHTHCFSDHGVGGHYHEDTTADCVEYEGYFNVGQILYRIDQPTYVCDFGKD +> +VKSQVLETPPLEDVAKALETGLKGCFEQASVSVVDCPDLTAEPYHLAAPGISGSTRLVDVGGVPNLMPLVDRSKVYNFKQVAKDI-LPGAFFIGAGAGSSRLAGVNCEMMPNTN-----ATQEIRSYFAKVRPE-TGDMV-LEHYE--SNEFGLLGNFLASEGKQGAVLRVEASVRTGDDNFVTCMRQSLQAAFG-KPVGLGGVFVIEAGDAKLHVMV-RGVHCAA-------------------------NGDAVGWILRVEHTHCFSQHGQGGHYHYDTTPANVKYVGYFSVAEHIYRVDAPKVTHQIGRD +> +IKEKPLFQPPLQEIVDVLSAGLTSTFETVNVSAEDSPDLTRSPYNLTSPGLTGNARLVEIGGPPYLLPLVQRDKLYDLAALAQHLQRDPALVAGAGAGPWPHIGVNCEGIINLSIRN--GTVDQGTRIVSVEPVSSRYLQRQLPSSESETRTALLGNYLLSEGKPGKVIKVVAKKRIGPSNFITAIRETLKNHYGDKIVGLGGMFLLRAGKVKFHVMP-DFSSSALCTDDDVDSWLHYFEMSAPITHVGTLVTGDHGLDLRVQHFHGFSQHGDGGHYHYDTTPEAVEYEGYFALASHIIRVDAPDQTHAVGRD +> +ITEKALYVPPLEEVVDVLARGLPDTFETVSVSVVDAPDLTQEPFSLTSPG---DVKLVEIGGPPYLVPLVKRDKIYDLHLLLQHLKRDPGFLAGAGAGPWPYLGVNCEGIINLSVRN--GSVEQGTRIVSVEPVSSGFLQQRLPNTE---RTALLGNYLLSEGKPG--------------------------------------------KAKFHVMP-DFSGTALCSDSDVDGWLHYFELSAPIVNVGTLVTGDLGLDLRVQHFHGFSAHGHGGHYHYDTTPDAAHYEGYFSLAHSVVRIDPPAETHALGRD +> +IQTKALYVPPLEEIADVLSRELRSNFETVEVSVVDCPDLTQPPFDLQAPGISGNATLVEIGGPPYLVPLVQRDKVYDLAALLRHLRRDPALLVGAGAGPWPYIGVNCEGIINLRLQD--GAVRQGTRVVSVQPVSSGYLQRRLPDGE---RTALLGNYLMSEGAAGKVVRVVAKRRVGGDNFITAIRGALRARYGERGVGLGGAFVVREGRVKHHVMP-DFSSAALCSDEDVDRWLHYFEMRAPIVHVGTLVTADLGLDLRVQHFHGFSAHGDGGHYHYDTTPDSVHYEGYFTPADTIVRVDAPRETHAFGRD +> +LHKEMLSCSRVSSYGGNQQNGESSAXLSVSRAARSFTGWTGKQFC-RSSGLCGNPRITDVGGVPYLVPLVKKNKEYNMNAVSKELELPGAFILGAAAAPSRVIGMNAELMPLVLTEAEGRPAVNCSYFASINPADGQCLQEKYADRFSDCSFGLLGNLYACEGKPGKVIEVRAKRRTGSDSLITALRTTLEAHYPGESLALGGTFLIQKGKAKIHIMPREFSACPLNTNDDVNNWLKHFEVSSPLICQSVLVSRDPGLDLRMEHTHCFSHHGEGGHYYIDTTPDTVEYLGYFLPAEFVYRIDRPKEMHRVGQD +> +VEKFAFHIPTLEEVADVLQNGLHGNFADVQVSVVDCPDMTQEPFCFPAKGICGKPRIADVGGVPYLLPLVQKEKVYDLNIIAKNIQLPGAFFLGAGAVSSRVVGSNAEFIPIVQAEKEEKAAVNGSYLAKINPEDGTCLLQKYSSLHKDYEFGLLANLYASEGLPGKVIEVRAKKRTGEQNFISCIRKALDKHYGDRTVGMGGTFIIQKGNAKLHIMPSEFSACPLETDEKVNNWLKFFEMTAPLICQPVIVSQDPGFDLRVEHTHCFSHHGEGGHYHTDTTPETVEYLGYFVPAEFLFRIDRPKETHMVGRD +> +-----------------LKSGLLKNFADVTVIETECPDLSKEPFEFPVYN---------------------------VNSVARKIGLPGAYILGAGATSHKSLGMNAD-----------------------------------------------------------KKTREQAESAGTVAVNKSVGSCLLEKYRDRNNDNNFGLLYNLACEGKTG----KSACQLNSDEDVNGWLKFYEMTAPLICQLVFVSHDPGYDLCLEHTHCYSHHVEGGHYHYDTTPNTLEYLGYFHPAEFLYRIDKPSDTHMVGRD +> +---------------------LAPYFRHLTTKVVECPNLGAKPFYLGRAGISGDATLANVGSYDYLIPCADHGKMYNFVDVARYSGISFGMVLGGGIGPFQAYQKPCEC-----------------E---------VPISERA--S--NNFFSATGQFFITEATPGKVIELKAAGRVNCHNIFDLIQKALYNKYSSSPVALGGVFFLQNSAVEVNLLN-DLPKEPYHTFPCFKEFQTTFKIEGPIIGTGTIVSHDPNQDLVTQSFYCWDTKQLTGHFENDICPDMANYTVYLYPARNILRLDKPYYR------ +> +----------------R------------------------APLVFKPARLSGQNVVCDVGSMKYLLPVIDKSKRYSFDEVAELSKIIHGQLLGAGAGPFFIHNKSCEMAANVEFSD-SKIISNSTLHGVYNETP-----EVIRAT--DNNFALLAHLLSTEGLPGSVIEVDVSGRLKEGSAYVFLREALTSAFGAKPVALGGVFALNDSKARFHVLC-GLPDHPVDTPEKVAAFVKHFEMEPPVLGVGTLVSHDPNVDLKLEHFHCYNEQTLAGHFYWDTEPEKAHYRFYLAVAKNLLRIDPR--------- +> +----------------VLERGLSMNLKKVKIEWMDCPDLRL--YGFVAPGLCGTPALLEIGSLSYFCPTPRLDKKYYFRELLSLLNLTGQFIVGAGTHIDPP-----------------------TY-----------DLAE---F--NSLCVIQGNFFLSERRPGKVLQVTAHCRTGPLNFVSAIQELFNLMRTDPLIGLGGMFMVSGSPTLHHIMP-AYSRVNLYTMKQVQQWLRYRKLIEPVTAVGTIMISDYLPYLTKSHFHSHNPRSCGGHFYTNCVNTDAFYVGYFSFAEKLYCVDPPSRRD----- +> +--NVSINTATLKDVRDVL-YNLREYFNKFEIDVGSCPPLTARPYNFDFNGLSGLNILEQNFPMEKNIPL---------------DES-------DPVRP--------------------------------------IRLHT------KYK-------FFTEDRPGMVLEMYARGRKTNQSIITLMQNILHRRFS-HKMGLGGILIVKGGQLLQYNPK--FT---CEATY------HHIKCDSEITCSGAIVNDPVGLNRYM-----HS-EHGNGFFVNDITPKETEYYGIFNVADAVCRW------------ +> +--IVHLNLPDLSEVKNVLEPALREYFNEANVSVVPCPDLRESPFHLAAPGLSGETIIMKMGGTEFWIPT------------------------------------------------------------------------H------NMD-------KSCNGDPGYVLKVNAKGRRTNVNFPTAIQTGLQRRYE-PFIGLGGTFVIKNGIVRNRLRC-PLD---LNSPS------EIHHTSTPLVAVGTILSRKTGL----HTFACNR-VDVGGHFLNDFSPLDTEYEGYFNLATKFIRV------------ +> +--TFPTNPPTLSEIAEVLQNGMQPLFQQLNVDIASCPRLTTAPYNLAGVGLGGNTTIIEFLHINDNVPWNH--KTRDIREILTSS-CRDSFIIGSSYASKPHMPRYGHLIMNATYRA-PMDLKNESR-------------------------------------------------L---IF--------------AERALGGVLKMKYGSVACNLMW-DDYQEPLLPFYEFIRRQTEIHLESDMVAVGTIVNTEPRLEQRRFAFHCFSDDGVGGQFVSDTTPDTTEYEGYFNVAENIL-------------- +> +--TFPTNPPTLSEIAEVLQNGMQPLFQQLTVDIANCPCLTKPPYNLAGVGLGGNTSIIDFVHYSEILPWYR--RRVNIQEILTSS-CPDSFVIGSSYATKPHMPHYGHLIMNATYRA-PMDLKNESR-------------------------------------------------L---IF--------------AERALGGVLKMKYGSVACNLMW-DDYQEPLLPFYEFIKRQPEIHLESDMVAVGTIINNEPGLEQRSRLCGQ---------------------------------------------- +> +--------------GQLLQNGMQPLFQQVTVDIASCPCLTKPPYNLAGVGLCGNTTIIDLVYRSEIIPWNR--RKVDIRKILRSS-CRDSFVIGSSYATKPRMPHYGHLIMNATYRA-PMDIKNESRLIFAERRNGQTTIEKLTDP--NQMKATQGIMFVSEGRAGLVIRVRAKGRKTITDIITSMQTILFERYRNENKDIGGVLKMKYGSVACNLMW-DDYQEPVLPFDEFIKRQQEIHLDSDMVAVGTIINNEPEL------------------------------------------------------- +> +TVVLRTFEASLEDIAAAFETGLKSCFQNVSVSVADCPDLTNKPFALPSSGLLGNNTVCDVGSFSYLIPVADTSRRYTFSEVISAS----QQLIGAGAGPFFTAGKNCEAMMGNRFNTENDVRSNNTLHGVYNKSE--DKPGVLKAT--DNNFALLGHFLATEGNPGKVLAVDVSVRAK-GSIYTFLREALTAKFGSAPVALGGAFVLDNSKGRFHVMP-DFPKKPVDSPAKISSWLKFYEMSPPVMGVGTIVSHD-VGFLSTEFVDCLLDFNNSSS-YGE--P---EFQTVLIVTPFFMRGNN---------- +> +TEKVQLHAPDLEELRGVLQTGLEDNFAEVQVNVVECPDLSKEPFQFPVKGLCGNPRITDVGGVPYLVPLVQKHKEYDMNSVSKEV----PFILGAAGAPSRIVGMNAE-------LMEGKPAVNSSYMSSINPADGQCLQEDR---FSGCSFGLLGNLYACEGKSGKVLEVRAKKRTG-HSLVTALRKTLEGHYP-KSLALGGTFIIQKGKAKIHIMPREFSACPLNTNDDVNNWLKHFEVSAPLICQSVLVSRDP--DLRVEHTHCFS-HGEGGHYYIDTTPDSVEYLGYFMPAEFVYRIDRPVDTHGVGRD +> +IVRIRLSEPPLSKIVEAVLPGLKKNFESVSVEVVPCPDLTQPPFYLATEGLSGNETVIDVGSPSYLLPSVNLDKLYDIKDFKKVI-SDPLSIVGAGAGPWPYVGVNSEFIGNVKHT------INRSHFYKINPETKGILHGNLPQN--ETRFALLANFYTSNGFSGEVLKIVCETRKGPLDFVSSIREALANYY-EETVALGGAILIENGKVKVHVMP-EFSKTPLNTETELNNWLNFFEVSTPLVGLGYLVSNDPGLDLRPQHFHLFSDHGFGGHYHYDTEPITIKYTAYLNVAKNLIRIDQPKKSLSFGKD +> +IEKGTFTNHSLEDIASALKKGLSENFKNVEVEVVDCPNLRE--WDCPSEGISGNQKIIDVGGEPYMHDPNFIGAEFDYEEISKMI----EYALGAGSGAMSCLGHCGELVINENSR---------SIIARVSPDK-KCIVEKY--S--ARKHGGLGNIYYTDGKQGKVIKIKIRGRSGDGSLPQVMRSSLKIK--NEHLSLAGVFRVLNGKIRSHVQP-DYKDIKHEYYKQMKDFLQFYEPGPKLQCYTVLWTGDPGGNLREEHTHFHSYDKDAGHYHFDVTPEEIEYEGYFNTATEVHRVNNIYKELLSKNS +> +TSEHILSPPPLEDIASILATVLQSTYTSSSATVVQCPDLRLPPFRLASAGLGGNESVADIGGQAHLFPRPVFSKKYSLLRIAELM----EMLIGAGAGPFHVLQQNSELAADLCKN-V----TNQTRFTKIDNAT-KLVTDI----CPSTDCALMMNVFGSAGDPGPVLRVTARGRRPTQSFPELVRQSLQEAYGR-QVSMGGVLVLKRGTAKFHVMP-DFPPEPFTDRGQLEQWLTYHDFAAPMVCLSVLHSCDPQ-GLRMEHTHCFSAGQQGGHYHYDLLPVEVEYEAYFNSAKVMYRIDQPDA------- +> +PNFCLMLNNSFVCLLLVLQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGQTRIAEVGGVPYLMPLVNKKKVYDLNEIAKEI----PFILGAGAGPFQTLGFNSE-------FMEHNHPVNGSYFARINPADGKCLLEQK---YHDFGCALLANLFASEGQPGKVIEVQAKRRTG-LNFVTCMRQTLEKHYG-KPVGMGGTFIVQKGTVKAHIMPAEFSSCPLTSDEAVNKWLHFYEMKAPLVCLPVFVSKDP--DLRLEHTHFFS-HGEGGHYHYDTTPDTVEYLGYFSPAQFLYRIDQPKETHAFGRD +> +VEEKPLYCPSLTDAAEALKDGLSETFETVEVSVVDCPDLTQKPFSLASQGLGGSPTILEVGGVPFLMPLVDRSKVYDFKDMNKVT----NFIIGAGAGPFTYAGVNCELVANLVVRQS-----QIAKLKDESKGD-EFVTETLQDS--VSSFALLANLFVSEGKPGKVIRVHCANRK-GSDFVTAARDSLLKGFP-KAIGVGGTFLVNGSKVKQHIMA-DFTTTPLDSEEKVT-------------------------------------------------------------------------------- +> +IKTYPLNPPPLSDFASLLTINLPSHFRDVSVSVVPCPDLTLPPFHLAAAGLSGNEKIADIGGPPYLHPLPNFSKKYSFLDLARLI-----FILGAGAGPFHIVGRNSELMPNLSGR---EKVLNLTKYAKVDE-Q-GCVCGPV--PGESTDFGLMANLFCSDGDPGEVLRIVAKTRTG-ENFTEAIQKVLRAEYG-RTVSLGGVFLVKKGKAMLHVMP-DFSKEPL-EHGMMDKWLKFYEVGAP-VCLSTFHSSEIE-GLRMEHTHCFGG--KGGHYHFDT--TEVEYEAYFNTAKVICRVDQPQIWN----- +> +IKTYALTSPSLPELASLLTKSLPSHFQDVSASVVPCPDLRQSPFHLAAAGLCGDEKIADIGGPPYLHPLPDFTKKYSFPELAKVL---PDFMLGAGAGPFHVVGRNSELMPNISKV-R-----NLTKYAKVNEQG-GCTCGPVPGN--STDFALMANLFCSDGSPGDVLKIIAKTRTS-ENFTSAIQSILKREYS-RPVSLGGIFLIRKGKAMLHVMP-DFSKEPLHQD-QMKEWLKFYEVEAPLVCLSTFHSHD--GALRMEHTHCFGGEGDGGHYHFDTTPEEVEYEAYFNTAKVVYRVDQPPVEG----- +> +VKKFLLHTPKIEEVAKVLNDGLKECFAEAEVEVTDCPDLRQKPFMLASEGICGKPRLSDVGGVPYLIPLAKTEKIYSIDDIMKCV-MPDGFAIGAGAGPHHIVGVNCEMMHNIKC---GPNAVSNTHYAK-IED-GKCALGTLPPE--KCEFCLMANILVSEGKPGKVLRVSAKCRTGEDNFVNAMRKILNKKYGTDPVGVGGVFVIQQGKAKLHVMP-HFSTKPLVTEGDVNNWLKFFTMSAPLVCLSTFVSHDPGWDLRIEHTHCFSDHGEGGHYHYDVTPTEVQYLGYFSIAEFMYRIDAPSVTHNIGRD +> +VDTQQLFVPSLSEVCDTLQDGLSRNFETVKVEVVDCPDLTQSPFCLSGRGLCGSPRIADVGGPPYLLPHVDRTKLYDIANLTKLI-LPNAFVVGAGAGPFPFVGQNSELMANVVT---GKNASNGSRICKII-N-NKCELHKLPQN--ETGCALMINLFASEGLGGKVLKVSARKRKGTDNFISCIRKTLDVKYE-KSVGLGGFFRVTSGTVKCHVMP-GFCDSALETEESLNNWLHFIDMPAPMTFFSVLVSRDPGMDLRQEHSHGYG-ESYGGHYHYDVTPDEVEYEGYFNIAEILYRIDRPEHTHSFRRD +> +IKSHPLAPPPLTDLASLLTTNLKPHFRDVSASVVRCPDLRQPPFHLAASGLCGNEKIADIGGPPYLHPFPNFTKKYAFLDLTKLL-MSPGFMLGAGAGPFHVVGRNSELMPNFS----GGAVMNLTKYAKVDEQ-GGCVCGPVPGN--SADFALMANLFCCDGSPGDVLKIVARTRIGKENFTAAIQKILKAEYG-RIVSLGGVFLIRKGRAKLHVMP-DFSKEPLEQ-EKTEEWLKFYECEAPLVCLSTFHSHDPGLELRMEHTHCFSEHGDGGHYHFDTTPENVEYEAYFNTAKIIYRIDQPPVEG----- +> +VVSRDFHVPSLDEVAGVFEAGLRANFATATASVVDCPDLTQAPFHLASEGICGSPRLADVGGVPNLVPLVNRDKVYNFVDVAKQI-LPGAFFLGAGAGSSRLAGVNCEMMPNTH-----ATHTIKSYFAKVDPE-DGSMV-LNPYS--SNEFGLLGNFLASEGRPGKVIKVEAETRTGDKNFVTCMREALHAHFGAMPVAIGGSFVIEAGNAKLHVMP-DFSKTPLQSDDEVAQWLKFYECQPPLTCLSVFVSHDPGMDLRVDHTHCFSQHGQGGHYHYDVTPKAVKYTGYFVVAEKVFRVDAPKETHTIGRD +> +TTKVNLDLPPLEDVADAFRDALLTNFDQVTVDVRECPDLRGEPWLFKTVGLCGKTAIADVGGVDNLHFAVNNYNSFSLQEVARTV----DFIMGPGAGNPNNVGINSELIVNNNIS-A-------SKVVTVKE-DGSYLQEDY--V--WSDVGPLANLYLSEG-KGKVVYVRAAVRKG-MNFPSLLRKSLVDGFK-RHIAVGGVFLIKTGNIKGHVMP-DFPKRDLPDTAAVNAWLKFYEMRSPLICTTVFLNGDIGLGFRQDHTHFWSHHGDGGHYHYDVTPEQVEYEGFFHLASEAHRIEPPKVPK----- +> +TFVINTLKPSNAELRSVIENALWKNYKNVQVTLTTCPDLSKPPFRMTANGFGRNLSIAEVGGMGNLFPILHKEKDYDIKIAS---------------------------------------------KATIQHGESPYKSLTI--D--SPKFNLMANLAISEEPGAEVVHVKCSERIG-ENLPRCIRKGLAWHYG-SCVSLAGIFLLLRGEADVHIVP-DYPPASFRTMDEVESWFNMFKVKAPLVCATVFHSYD-GNNLRMEHTHCYSDHQDGGHYHIDTTPETVEYEGWFTAAEKIYRVDQI--------- +> +LE-WKNLLFTYLLWKKWLMNGLQENFADVQVSVVDCPDMTRGPFCFPVKGICGKPRIADVGGVPYLLPLVQKEK-----------------------------------------FIEEKAAINGSYLAKIHPEDGSCLLQSL---YNDCEFGLLANLYASEGLPGKVIEVRAKKRTG-QNFISCIRKALDKHYG-KTVGMGGTFIIQKGNAKLHIMPSEFSACPLETDEKVNNWLKFFEMTAPLICQPVIVSQDP--DLRVEHTHCFS-HGEGGHYHMDTTPETVEYLGYFVPAEFLFRIDRPKETHMVGRD +> +AEFSF-HVPSLEELAGVMQKGLKDNFADVQVSVVDCPDLTEEPFTFPVKGICGKTRIAEVGGVPYLLPLVNQKKVYDLNKIAKEI----PFILGAGAGPFQTLGFNSE-------FMEHKPPVNGSYFAHVNPADGGCLLEEK---HHDFECALLANLFASEGQPGKVIEVKAKRRTG-LNFVTCMRQTLEKHYG-KPVGMGGTFIIQKGKVKSHIMVRAHV-C--------SFW----------FGLPVLVSRDPSIDLRLEHTHFFS-HGEGGHYHYDTTPDTVEYLGYFLPAEFLYRIDQPKESHSIGRD +> +------MFCNWTWIKGILWN-DSGGYRKMPSHKYQVSDFRQAPYLMTGSGIGSGLRIVEVGGIGNIYPVIKCDKFFDLKAICTKS----PFVFGPGAGPWHVIGSNCEMVADANNPVA-------SKIIKINADNKAYELSTT--N--SSYFSLMANLALSNANEADVVHIHVKKRLT-TNFPESVRRTVGAYYG-NLVSIAGIFLVKAGKIKMHVMP-NFPSPNYCWKDEVLK---YFEMSAPVICACVIHSTNNERKLRMEHTHCYSEHGDGGHYHCDLSPEIVEYEGYFAPAESVYRIDLV--------- +> +--------------------------------------------------------------------------------------MPDGFVIGAGAGPHHIVGVNCEMMHNMKCGA--NAVSNTHYAKIE---DGKCSLGSLPPE--KCEFCLMANILVSEGKPGKVLRVSAKHRTGEDNFVNAMRKILNKTYGTEPVGLGGVFIIQQGKAKLHVMP-HFSTTPLVTDKDVNDWLKFFHMRAPLVCLSTLISHDPGWDLRIEHTHCFSDHGEGGHYHYDVTPEEVEYLGYFNIAEFMYRVDAPTVTHNIGRD +> +-EEKELFVPEMETLCSVIETGLKSNFSDVSVSVVDCPNLSQAPFHLASSGLGGDATLVEFGSPVYLLPLVNKSKIYDIVELLRNISSYEEFTCGAGAGPFPIFNQNCEGMLNIRVGS-DGTLKNETHVARIVPG--GVELSKVPDQ--ETRCALLGNLYLSEGKAGKVLKVTAKRRTGSENFISSMRLALAEYFTDKTVGLGGTFLIKEGKAKQHVMD-EFSKVPLYTEDDVNKWLTFHEMSAPLIAVGTFVTNEADLDLRLQHFHSFSKHGEGGHYHYDVTPDTVEYEGYFAVGRRIIRIDKPEQKLK---- +> +--QHVRQPPALEELAAIIQQSLQSNFETASASVVQCPDLRQPPFKLAAPGLCGEACIGDVGARGNLFPRPNLNAKYSLLSLAEDMKMSTEFLIGAGAAPFQDIGQNAELAVNLSWQGSSLVVENKTHVVRISQDS-TSTCKTT--T--STNCALMMNLFGCHGEAGPVLKVTARSRRGKDNFTNCIRHGLYAAYGTRPVSLGGVFLLKSGKAKFHIMP-DFPPEPFPDREYMQRWITYHVFKAPIVCLTVLHSADPGLGLRMEHTHCFEGHRQGGHYHHDINDGEVEYEAYLNAASLLYRIQ----------- +> +TEKVQLHAPALEELRGVLQAGLETNFAEVQVSVVECPDLTTEPFLFPVKGLCGNPRITDVGGVPYLIPLPQKHKEYNMNIISKELELPGAFILGAAAAPSRIIGMNAELMPLVLTEAEGRPAVNGSYFSSINPADGQCLQEKYSDKFSDCNFGLLGNLYACEGKPGKVIEVRAKKRTGSNSLVTALRKTLEAQYPEKSLALGGTFVIQKGKAKIHIMPREFSACPLNTNDDVNNWLKHFEVSAPLVCQSVLVSRDPEDNTRPSLIRCTKDHGSA--------------------------------------- +> +-QKYPLSPPSLSALAAVLQPALSRNYAHCSVSVSPCPDLRQPPFHLAAQGLSGDEKIAEVGGQSNLFPSPDLSAVWSLPEIARDAGMDAAMLLGAGAGPYRDVGQNSEWAPCYSWED--NKVRNESRCALVRKDTGKVEVRKQ--D--SLGCALMCNLFGSRGEPGDVLRITARRRTGDASFTECVQAALREAYGSTVVSLGGVVLIKKGLAKYHVMP-DFPDEPFRDLDQLMKWLTWHEYRGPIVGLTVLHSADPGGGLRLEHTHTFSAEDAGGHYHYDIEDEDVEYEAYFNTAKSPIHW------------ +> +----------LYDVCSTLECYLTPYFGHLTAKVVECPNLNQRPFYLGRSGICGDSTIANVGSLDYLLPCADPSRLYDIMDITKYTGHCQGMILGGGVGPFQCYKKPCEVSTEITYST-RGLQCNRSLIGFCSKECGSPSSERA--S--NTLLSSLGQIFITEAMPGKVVEIVAHKRIGGPSIIDLMQAALYDKFSELPMALGGVFYLQNSGAQASVLC-ELPQEPYHTFPCLKKYQTSFNIDGPIIGVGTVLSHDPKMGFSMASFYCWNSRLLTGHFENDICPEKATYTVYLTPAKKLYRQDKPVHN------ +> +-AKIVLKTPPLEELSSILCAELKKNFVDVSVDIVDCPNLRAPPFRMSGAGIGNDLRIGEVGGIGNLFPSPKTDKFFNLKKICETCEMPKAFVFGPGAGPFHIVGNNCEMVADADFTTD-HQNNVATKVSRVVPNGKGYEMSTI--D--NADFVLMANLAISDGFAGKVLRVHAAKRNGEMNYPGAIRKALIGYYDGMAEVFRN-----ESAISMCIGI-AFE------------------------------------------------------------------------------------------- +> +-----------------LTGFMSGCFSKVACQVVDCPNLKDPAYALNSAGLCGSETLCDIGSFDYLLPVPNKEKRYDLLDAFSLSHVGSGFIMGAAAGPHFVAGINSELVANLSATD-GKVLQNGSYCGSYDAKN-NLPVSTL---SETSLFAMVGQMFLCEGKPGKVIQLTVSGRTREGKFDALLREALASKYGDRPVGVGGVVVQETGKCLFHVLP-EFCEEPLDTPEKLKQWLKFFEMEAPVVAVGTALSHDPKWKIRLEHFHCFNDRTKSGHCHFDSDGPTASYTAYLVPGKRLLRVDPPK-------- +> +---------------------IKDHFKSVNVRIVPCPDLKASPFRLLCSGLSGQNIVCDVGGMSYLLPVPDKTKMAANVRFEDSK-ISSNSTLHG------VYDES--T-----------------R---------SPQVLAA--T--DNNFALLAHLLATEGLPGDVIEVDASGRLKEGAPYVFLREALTSAYGDKPVALGGVFMLTGSKGRFHLQP-DFPDHPVDSPSRVAEFLKFFEMEPPVMGMGTLVSHDPGIDLKLDHFHCYNERDLAGHFYWDTEPQTAHYKFYLTVAKSLLRIDPKPK------- +> +---------------AVLQKGLKTNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLINR---------------------------------------------------------------------------------------------EKVIEVKAKRRTGQLNFVTCMRQTLGNHYGDKPVGMGGTFIVQKGKVKTHIMG---------------------------------------FDLRLEHTHFFSHHGEGGHYHYDTTPETVEYLGYFLPAELLYRIDQPKETHLIGRD +> +--IIETHKPSNGELLSVIEEALQANFKVVETKLCQCPDLASEPYNMTSSGFGRKLVIAEIGGPGNLFPVIHREKEFDLKEICDNCEAPSSFVFGPGAGPWKVVGRNCEMVADANFSSS----KVATKIASIPPNHTAYKMEVI--D--SRKFSLMANLAISAPGPAEVVYCKASVRTGKDNFPEVIRKGLAQHYGKKCVSVAGIFVMLKGKAKLHVMP-DFPGCNFKSTEEVIEWSIAMEMQ---VCFSALLVKA---------------------------------------------------------- +> +-------------------------------------DLSVEPCSMTSSGFGQKLVIADVGGPGNLFPKIHKEKEFDLKEICKACQSPFSFVFGPGAGPWKVVGRNCEMVSDANLTTA----KVATKIASLPPGHPPYKMDVI--D--SPKFNLMANLAMSEPGSGEVVHCKYSVRIGKDNFPETIRKALVKHYGES----------------------------------------------------------------------------LGHYYYDTTPDTVAYEGWFTAAEKIYRIDE---------- +> +---------------------------------------------MSSNGFGKNISIAEVGGMGNLFPRLHKEKEYDIKEICELCDKKSAFVFGPGACPKSVMGTTGELVADV-----------ASKVTNLVNNHSPYKTCEI--D--SPKFNLMANLAISQPEPAEVGNLTV--RVDGSDVPEKL-----------WPE----------------------------------------------------------------------GNLERHYYNDVSPKTVTYEGWFAAAERIYRIDE---------- +> +---INTLKPSNAELRSVIETALWKNFKNVQVTLATCPDLSKPPFRMTANGFGRKLSIAEVGGMGNLFPILHKDKDYDIKYVVNLCGKKSAFVFGPCACPASVIGTTGALVADVNFTSS-----QIASKATIQQKGHTSPHKSLIIE--SPKFNLMANLAISEE-PG--------------------------------------------------------------PAEVEKWLHRFKVKAPLVCATVFHSYDPEFNLRMEHTHCYSDHDDG--------------------------------------- +> +---IKTFKPSNSELCSVLGAALKKSFKKVHVELTKCPDLTAAPFHMTGTGFGRNMVIAEVGGLGNLYPGFHKEKHYDLKVAE----------------------------------------------------NKSVPFETKTIN--STKFTLTGNFIVTAE-PGPAEVVHIKCSERTGKLCFPDTLRESLEQRYGECVVLGGLFRLLRGKARVHIAPEFPEKPWKSMDEVEHWYQPFVVSAPLLCASVMHSYDPGFKLRMQHTHCISDHNDA--------------------------------------- +> +---INTLKPSNHELRSVIEAALWKNFKNVQVEVEKCPDLTAAPFHMTSPGFGRNLVIAEVGGWGNLFPNLHKEKLYDIKEICNTCGAPKAFVFGPGGCPPSAVGVNGELVADANLSEN-----KVSSKVTIQLDHYTSPYKTLFVN--STKFVLMGNLAITPE-PG--------------------------------------------------------------PAEVGKCQKLPEFREIL-------------------------------------------------------------------- +> +----NTLRPSNAELRSVIENALWKNYKNVQVTLTTCP----------------------------------------------------AFAFGPCACPASVAGTAGELVADANFAES----KIASKATIQQGGH-TSPYKSLTID--SPKFNLMANLAISEEGPAEVVHIKCSERIGEENLPGCIRKGLARHYGQSCVSLAGIFLLLRGEADVHIVP-DYPPASFKTMDEVEKWLQRFEVKAPLVCATVFHSYDPGFNLRMEHTHCYSDHDDG--------------------------------------- +> +--EIPLLTPTISEIAEVLHNEMQPLFHEVNVDIASCPCLTVAPYNLAGVGLCGNTSVIMYYPE-NSEGWNH--RTKNIRDMLTAS-CRDSFVIGATYATKPSMPYYGHLIMNATYRA-PNGIRNESRIISA------------------------------------------------------------------NKALGGVLRIKNGRVACNVMW-DDYEEPMPRFYDFIQQQQEIDVESDMVAVGTMLSEKPELEQRRSEFHCFSNIETGGQFISDTTPDTTEYEGYFNVAEQIN-------------- +> +--IHPLTPLNLSEIAEVLQNGMQSLFHDVRVDITRCPYLTTAPYNLAGVGLCGNTAVVEFLRHDQNVPWNR--RTKDIQQLLTCS-IRDSFIIGSTYATKPNMPYYGHLIMNATYKA-PMGIRNESRLIFA------------------------------------------------------------------ELALGGVLKMTNGSVACNLMW-DEYQEPISPFPDFVREQQEICLESDMVAVGTILNNEPKLEQRSQL--CGD-------------------------------------------- +> +--RTSWNSATLKDVRDVL-YKLHDYFDHFEIALVACPCLKKSPYNLDFAGLSGNMYIEELKSPVNMLPNIT---------------V-------PQAGP--------------------------------------IPFRS------NRN-------FYSDGKPGMVLKIRARGRRTDHSIITLIQSILHKRFS-YKMGLGGVLLMIGGRVARHIPE-TFP---LVLSE------RYLDCNPAVSAICTIVNNPVDLDLYYYESHCFF-GNEHGLFVNDVTPKDTEYVGYFNVAEKVYRV------------ +> +--TIPANPPTLSEIAEVLQNGMQPLFQQLNVDIASCPRLTTAPYNLAGVGLGGNTSIIEYLHRNDNAPWNH--ITWDIREILTTS-CRDSFVIGSSYAAKPHMPHYGHLIMNATYRANPMDLKNESRLIFAERRNGQTTIEKLTDP--NQMKATQGIMFVSEGRAGLVIRVRAKGRKTITDIITSMQTILYERYKNENKVVDGVLKMKYGSVACNLMW-DDYQEPVLPFYEFIKRQQCIYLESDMVAVGTIINYEPKL------------------------------------------------------- +> +--VYPLVPLTLLEVVEVLQNGMQPLFHDVKVDIARCPYLTTAPYNLAGIGLGGNTSVVEFVH--DGIPWNY--KTRNIQDVLTTS-CRNSFIIGSTYATKPHMPYYGHLIMNATYRANPIDIKNESRLIFIERRNRQTKIEKLTDP--NQMIYNKGSFFVSEGREGLVIRVCAKGRKTITDIITSMQMVLYEKYCNEDKVFGGILKMTNGSVACNLLW-DHYEEPILEFHDFIRRQQCIYLESDMIAVGTIINDKPQL------------------------------------------------------- +> +--VYPLEIPTLLEIAEVLQNGMQPLFQRVNVDIASCPNLSTAPYNLAGVGLGGYTSIVELFLLEPNVPWNQ--RTRDFQEIFTTS-CRDAFVIGTSYATKPSMPYYGHLIMNATYRA-PMDIRNESRLIFAERGNGQTRIEKLTDP-NQMKYTNKGIFFVSEGRGGHVIRVRAKGRK---TINTDIITVLYEKYENDNKFVGGVLKMTNGSVACNLMW-DDYEEPLGSFDDIIRRQQCIHLESDMIAIGTIINDKPVL------------------------------------------------------- +> +--KVTTLVPPLNDFGKAIQEYMKKNFSGVFVEVVPCPD---------------------IGGNAHLCPVPRPDIYYKLE-------FSKGFMFGPGAGPCYVIGVNSEMVADASFSEAPENVA--IKVGFTS-GKKEVGCKMMITD--KPEFCILGNLAIR--------KIRAFGRLS-------------------NVA-------------------------LT--------EQYFELDSPVVCTTVIHIRDVQCNLRLDYTHCYTD-SNAGQFYGDTEPERMEYVDYFVIAEAVYRIDK---------- +> +-RTIDLHVPDPTTITNVLTHALSMNFSEVAVECIDCPDLRQ--YRLVAPGLCGNPAILEIGSLSYLFPQPRLDKKYYFKNILRQLNLTSQFIIGAGNHSYPPNYDHSELYANFMFSPGSMDVQNKRITVWSTMENNNCMHE--------------------------VCKINPL---------------------CAIQGLGGIFATFHESNLYHIMP-AFSKADLYTMNQIQQWLKYSHGSDTASSVGTIMSEG---------------------------------------------------------- +> +--CFRLHRPDLAAVADCLDRACRDAFEDASVELIDCPDLSEPPFCLAGRGICG-------GGGENSGPVEQ--RRYDLRNLLKATGHLDGLIIGAGAASSTRFGRNAELVANLGPL------GNGCRVASLRADGANCRLSRP--D--FAEAGLMVDSLCSSGQTGPVLRLRASRWRPEGRLAELLQRALAKEF----------------------------------------------------------------------------------------------------------------------- +> +-VEYSFHVPSLEELVVVLQKGLKGNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNKEKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNAEFMPVIQIGSEHKPAMNGSYFAHINPADGGCLLEKYSEKYHDFGCALLANLFASEGQPGKVIEVKAKRRTGKLNFVTCMRQTLEKHYGDKPVGMGGTFVIEKGKAKTHIMPAEFSSCPLNSDEEVNKWLHFYEMRAPLVCLPVFVSKDPGFDLRLEHTHCFSHHGEGGHYHQDTTPDTVEYLGYFLPAEFLYRIDQPKETHLFGRD +> +-TEFSFHVPSLEELAEVLQKGLKDNFAHVQVSVVDCPDLTKEPFTFPVKGICGQTRIAEVGGVPYLLPLVNKKKVYDLNEIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPIVQTASEHHQPVNGSYFARANPADGKCLLEKYSQKYPDFGCALLANLFASEGQPGKVIEVQAKKRTGEHNFVSCMRQTLEKHYGDKPVGMGGTFLVQKGKVKAHIMPAEFSSCSLNSDEAVNQWLNFYEMKAPLVCLPVFVSKDPGLDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAQFLYRIDQPKETHAFGRD +> +-AEFPFHVPNLQELAAVMQKGLKENFADVQVSVVDCPDLTKEPFAFPVKGICGKTRIAEVGGVPYLMPLVNKTKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPIVQAESEHRPAVNGSYFACINPADGGCLLEKYSEKHDDFGCALLANLFASEGKPGKVIEVKAKRRTGQLNFVTCMRQTLEKHYGDKPVGMGGTFIIQNGKIKAHIMPGEFSTCPLNSDEDVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHFFSNHGEGGHYHYDTTPDTVEYLGYFVPAEFLYRIDQPKETHSVGRD +> +VEKFSFHVPSLEELVGVLQNGLKNNFADVQVSVVDCPDLTKEPYTYPVKGICGKPRIIEVGGVPYLLPLVNKKKVYDMNIIAKEIEFPGAFILGAGAAPFQTLGINAEFMPVVQTKSDHKPAVNGSYYAQINPEDGGCLLEKYSKKYNDFGFALLANLFASEGQSGKVIEVKAKGRTGEYNFVTCMRKTLEKHYGDKPVGMGGTFVIQNGKVKVHIMPPEFSSCPLTSDEDVNNWLHFFEIKAPLVCQPVFVSRDPGFDLRLEHTHCFSHHGEGGHYHYDTTPDTVEYLGYFLPAEVLYRIDKPKETHTFGRD +> +-AEYSFHVPSLEELVGVLQKGLMDNFAEVHVSVVDCPDLTKEPFAFPVKGICGKTRIAEVGGVPYLLPLVNKKKVYDLNKIAKDIQLPGAFILGAGAGPFQTLGFNSEFMLLVQAENEHKPPVNGSYFARVNPADGGCLLKKYSEKYRDFGCALLANLFASEGQPGKVIEVKVKRRTGKLNFVTCMRQTLEKHYGDKPVGMGGAFIIQKGKVKTHIMPAEFSSCPLNSDEDVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHCFSHHGEGGHYHYDTTPDIVEYLGYFLPAELLYRIDQPKETHSFGRD +> +-AEFPFHVPSLEELAGVLQNGLQENFADAQVSVVDCPDLTKEPFTFPAKGICGKTRIAEVGGVPYLMPLVNKKKVYDVNKIAKEIRLPGAFILGAGAGPFQTLGFNSEFMPVIQTEGAHTPPVNGSYFARVNPADGGCLLEKYSEKHQDYGCALLANLFASEGQPGKVIEVKAKRRTGKLNFVTCMRETLEKHYGDKPIGMGGTFLVQKGKVKAHIMPAEFSSCPLNSDEDVNKWLQFYEMQGPLVCLPVFVSKDPGFDLRLEHTHFFSHHGNGGHYHYDTTPDTVEYLGYFSPAEFLFRIDQPKETHSIGRD +> +-ERFAFHVPSLEELVGVLQNGLKANFADVQVSVVDCPDLTKDPFTFPAKGICGKPRIADVGGVPYLIPLVNREKIYDMNVVAREMELPGAFILGAGAAPFRTLGVNAEFMPIIQAESEERRAVNGSYIAQINPADGGCLLEKYSEKYEDCDFGLLANLYASQGQPGKVIEVKARGRTGKHNFVTCMRETLGKHYGDKPVGMGGTFVIQKGKAKVHIMPPEFSSCPLNSDEDVNNWLKFFEVKAPLICQTVFVSRDPGFDLRVEHTHCFSHHGEGGHYHYDTTPDTAQYLGYFLPAELLYRIDRPKETHLVGRD +> +-AEFPFHVPSLSELAEVLQKGLKDNFADVHVSVVDCPDLTKSPFTFPAKGICGKTRIIEVGGVPYLLPLVNKTKVYDLNKIAQEIKFPGAFILGAGAGPFQTLGFNAEFMPIVQTASEKKSPVNGSYFAQVNPADGDCLLEKYSEKYHDFGCALLANLFASEGQPGKVIEVKAKRRTGVLNFVTCMRQALEKHYGDKPVGMGGTFLVQKGTVKAHIMPAEFPSCPLNSDDDVNKWLRFYEMQAPLVCLPVFVSRDPGFDLRLEHTHFFSHHGKGGHYHYDTSPDTVEYLGYFSPAEFLFRIDRPKETHSIGRD +> +-NEFSLHVPTLKELAGVLQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLMPLVNKKKVYDLNKIAQEIKLPGAFILGAGAGPFQTLGFNSEFIPVVQTESEHNPPVNRSYFAWINPVDGGCLLEKYSEKYHDFGCALLANLFASEGQPGKVIEVKAKKRTGQLNFVTCMRQALEDHYENKPVGMGGTFLIQKGKVKAHIMSAEFSSCPLTSDEQVNEWLNFYEMKAPLICLPVFISRDPGFDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAQFLYRIDQPKETHSFGRD +> +-AEYSFHVPSLEELAGVLQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEIGGVPYLLPVVNKKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNAEFMPIVQTESEHKSPVNGSYFARVNPADGGCLLEKYSEKYRDFGFALLANLFASEGQHGKVIEVKAKRRTGKLNFVTCMRQTLEKHYGDKAVGMGGTFIIQKGKVKTHVMPAEFSSCPLNSEEEVNKWLNFYEMKAPLICLPVFVSKDPGFDLRLEHTHFFSHHGEGGHYHYDTTPDIVEYLGYFSPAELLYRIDPPEETHSYGRD +> +-AEFSFHVPSLSELAEVMQKGLKDNFAEVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLMPLVNKKKVYDLNKIAKEIKLPGAFMLGAGAGPFQTLGFNSEFMPIVQTESEHNPPVNGSYFSYINPADGGYLLEKYNKKYHDFGCALMANLFASEGQPGKVIEVKAKRRTGQLNFVTSMRQTLGNHYGNKPVGMGGTFIVQKGKVKAHIMPTEFSSCPLNSDEEINKWLNFYEMKAPLVCLPVFVSKDPGFDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAEFLYRIDQPKETHGFGRD +> +-AEYSFHVPSLQELAGVLQKGLKEDFAQVQVSVVDCPDLTKEPFTFPAKGICGKTRIAELGGVPYLLPLVNKKKVYDLNKIAKEIKLPGAFILGAGAGPFHTLGFNSEFMPVIQTESEHKAPVNGSYFARVNPADGGCQLEKYSSKYRGFGCALLANLFASEGQPGKVIEVKAKRRTGELNFVTCMRQTIENHYGDKPVGMGGTFLVQKGKVKTHIMPAEFSSCPLNCDEDVNKWLHFYEMTAPLVCLPVFVSRDPGFDLRLEHTHLFSHHGEGGHYHYDTTPDSVEYLGYFLPAEFLYRIDQPKETHSFGRD +> +VEKFAFHVPTLEELVGVLENGLKENFADVQVSVVDCPDLTQEPFKFPAKGICGKPRIADVGGVPYLVPLVQKDKVYDLNTVAKEIQLPGAFFLGAGAVSSRIVGGNAELIPVVLAKNEGKAAVNESYVAKINPEDGGCLLEKYKSKDKDCEFGLLANLYASEGLPGKVIEVRANRRTGEQNFISCIRKTLEKYYGDKPVGMGGTFVIQKGKAKIHVMPSEFSACPLNTEEDVNHWLKFFEMKAPLVCQPVLVSQDPGFDLRVEHTHCFSHHGEGGHYHTDTTPETVEYLGYFVPAEYLFRIDRPKETHMVGRD +> +VEKFALHIPSLEEIVGVLQSGLKENYADVQVSVVDCPDLTQKPFGFPVKGICGQSRIADVGGVPYLLPLVQKDKVYDLNDIAKEIQLPGAFFLGAGAASSRIVGGNAELMPVVQAQKENKPATNGSYIARFKPKDGGYLLEKYNTKYHDCEFGLLANLYASEGLPGKVIEVKANRRTGEQNFISCIRKALEKHYGDKPVGMGGTFVMQKGKAKIHVMP-EFSTCPLNTDEEVNNWLKFFEMTAPLICQPVLVSRDPGFDLRLEHTHCFSHHGDGGHYHTDTTPETVEYLGYFAPAEYLFRIDRPKETHMVGRD +> +-DRKEAFVPPLDELAAVLQAGLSTNFLDAKVKVVDCPDLTQPPFTLAAPGLCGSPRVADVGGVPYLIPTPQLDKKYNLEQVAGQVDLPGAFVLGAGAGGAHVVGVNCEMMPNIRTTGGAHSRNNQTRISRVNTEDGTCILEHYEETYQCRDFCLLANLFFSEGKPGKVLEVKAKVRTGQENFVSCMRKTLEQQYGDRPVALGGTFLLEKGQAKIHIMP-GFSQTPLQSEQDVNNWLNFFEMSGPLINLSVFVSRDPGLDLRVEHTHCFSHHGEGGHYHYDTTPEEVEYRGYFLPAEYIYRVDRPKISHMIGRD +> +VEKFDFHVPSLEEVVSVLQNGLKENFADVQVSVVDCPDLTQEPFRFPVKGICGKPRIADVGGVPYLLPLVQKDKVYDLNTVAKEIQLPGAFFLGAGAVSSRVVGGNAEFIPVVQAEKEKKAAINGSYIAKINPEDDGCLLQKYSSLYNDCEFGLLANLYASEGLPGEVIEVRANRRIGEQNFISCIRKALEKHYGDKPVGMGGTFIIQKGKAKLHIMPSEFSACPLKTDEELNNWLKFFEMKAPLICQPVIVSQDPGFDLRVEHTHCFSHHGEGGHYHMDTTPETVEYLGYFVPAEFLFRIDRPKETHMVGRD +> +-VEYALYMPSLEEFVGVLQKGLEDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIVGVGGVPYLLPLVNKKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPVVQTESEHKPPVNGSYFACINPKHGGCLLQKYSEKYHDFGCALLADLFASEGQPGKVIEVKAKRRTGKLNFITCMRQTLEKHYGDKPVGMGGTFILQKGKVKTHVMPPEFSSCPLNSEEELNRWLHFFEMKAPLICQTVFVSKDPGFDLRLEHTHFFSHHGEGGHYHYDTTPEVVEYLGYLSPAEFLYRIDQPEETHSFGRD +> +-ERFAFHVPSLEELAGVLQKGLKENFADAQVSVIDCPDLTKEPFNFPVKGICGKPRIADVGGVPYLIPVVQKEKVYDLNTVAKDIELPGAFILGAGAASSRILGVNAEFIPVVQTQSDKKPAVNGSYIAQINPVDKGCLLEKYSSKYTDCEFGLLANLYASEGQPGKVIEVKANGRTGELNFVSCLRQILEKHYGEKPVGMGGTFVIQKGKAKIHIMPPEFSACPLNTDEDVNNWLKFFEMKAPLVCQPVIVSRDPGFDLRTEHTHCFSAHGEGGHYHNDTTPDSVQYCGYFLPAEFLFRIDRPKETHMVGRD +> +-NKVKLHTPSLRSVSEALSEGLQNNFAEVNVSVVDCPDLRKEPFMLASEGICGHPRLADVGGVPNLIPLPQKDKIYNLETIAKQVELPNAFIIGAGAGPSHFVGVNCELMPNINIGDN----QNNTHFATVAEDG-KCHLEKL-RD--STDFRLLANLFASEGQQGKVICIHVKKRTGPDNFVTAIRKILLNNYKDQPVGVGGSFLIKNGKAKIHVMP-HFSETPLKTDEDVNNWLKFYNMSAPLVCLSVFVSHDPDLDLRVEHTHCFSNHGEGGHYHTDTTPDDVEYLGYFNIAEYMFRIDPPTETHLIGRD +> +VEKFAFHVPSLEELAGVLQKGLKENFADAQVSVVDCPDLTQEPFNFPAKGICGKPRIADVGGVPYLIPLAQKEKVYDLNTVAKDIELPGAFILGAGAVSSRVVGVNAELIPIVQTKNEKKPAINGSYIAQINPADKGCLLEKYSSKYSDCEFGLLANLYASEGQPGKVIEVKANGRTGELNFVSCLRQILEKHYGEKPVGMGGTFIIQKGKAKIHVMPPEFSTCPLNTDEDVNNWLKFFEMKAPLICQPVIVSRDPGFDLRLEHTHCFSHHGEGGHYHTDTTPDAAQYRAYLAPAELLFRIDRPKDTHSVGRD +> +-AEFSLHVPSLEELAEVLQKGLKENFAAAQVSVVDCPDLTKEPFAFPVKGICGKTRIAEVGGVPYLMPLVNRTKVYDLNEISRKIKLPGAFILGAGAGPFQTLGFNSEFMPIVQTESEHSHPVNGSYFARVNPADGGCLLEKYSQRGHDFGCALLANLFASEGQPGKVIEVQVKRRTGQLNFVTCMRQTLEKHYGNKPVGMGGTFIVQKGKVKAHIMPAEFSSCPLTSDEAVNHWLHFYEMTAPLLCLPVFVSKDPGLDLRLEHTHFFSHHGEGGHYHYDTTPDLVEYLGYFSPAQLLYRIDQPKETHLFGRD +> +IKEKPLFQPPLQEIADVLSVGLTSTFETVSVSVADTPDLTQSPYNLITPGLTGNAKLVEIGGPPYLLPLVQRDKVYDLAALARHFNSDPALLAGAGAGPWPHIGVNCEGIINLSIHN--GSVEQGTRIVSVEPVTSGYLQRRLPNT--ETRTALLGNYLFSEGKPGKVIKVVAKKRIGPSNFITAIRETLKNHYGDKIVGLGGLFMLRAGKVKFHVMP-DFSSSALCTDADVDNWLHFFEMRAPITHVGTLVTGDHGLDLRVQHFHGFSEHGDGGHYHYDTTPDDVHYEGYFALAASIIRVDAPEETHAVGRD +> +-AKHQLHCPSLEDVAKVLNDGLKNTFEHVEVSVVDCPDLKEKPFMLASEGICGKPCLADVGGVPYLVPIVQKDKIYNLEQVVKQTNVSDPLVIGAGAGPFNVVGVNSEMMHNMKYGD---KPFNNSHYAKINEDG-SYELGRFTTS--CCEFGLMANLMISEGKPGKVIRVSAKKRTGADNFVTAMRKALAAHYGTDPVGLGGAFLLAKGKAKLHVMP-KFSTAPLLTNEAMNSWLKFFEMEAPLVCLSVFVSHDPGWDLRIEHTHCFSDHKQGGHYHYDTTPEEVEYLGYFNVAECMFRIDAPASTHQIGRD +> +-AEFSFHVPSLEELAGVLQKGLRGNFAEAQVSVVECPDLTQAPFTFPAKGICGKTRIAEVGGVPYLMPLVNLKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPVIQTESEHRAPVNGSYFARVSPADGGCVLQKYSEKYHDFGCALLANLFASEGQPGKVIEVKAKRRTGKLNFVTCMRQTLENHYGEKPVGMGGAFLVEKGQVKAHIMPAEFSPCPLTSDEEVAEWLRFYEMKAPLVCLPVFVSKDPGLDLRLEHTHFFSHHGEGGHYHCDTTPDTVEYLGYFSPAEFLFRIDQPMESHSFGRD +> +-VKHSLHRPDLDEVAKVLNDGLKSTFEHVEVSVVDCPNLKEKPFMLASEGICGKPRLADVGGVPYLVPIVQKDKIYSLEEIMRKTEVSDGLAIGAGAGPFNVVGVNSEMMHNTKYGE---KPFNNSHFAKINEDG-SYELGRFTTM--CCEFGLMANLHISEGKPGKVIRVSAKRRTGNDNFVTAMRKVLAAHYGSNPVGLGGAFLLAKGKAKLHIMP-KFSTAPLLTNEAMNSWLKFFEMDAPLVCLSVFVSHDPGWDLRIEHTHCFSDHKQGGHYHYDTTPEEVEYLGYFNVAEWMYRIDAPASTHQIGRD +> +-EKSAFHVPDLEELCRVLQDGLKKNFANVQVCVVDCPDLAQEPFTFAAAGICGKPRIADVGGVPYLLPLPQTEKIYNLNVVAKEVELPGGFILGAGAASFKAMGVIAELMPNVSTKGNGKPEVNHSYSAKIDPATGGCVLERYGETYKTCDFALLANLFISEGKPGKVVQVRSSRRTGQSNFVSCMRETLEQHYGDKPVGMGGTFLIQTGKAKLHVMP-EFSTCPLNSNEAVNNWLKFFDMSAPLICQSVFVSRDLGFDLRLEHTHCFSHHGEGGHYHYDITPDNVEYLGYFVPAEYLYRIDRPEKTHKIGRD +> +-ASKSLFVPPLEELVEVLGSGLVSNFETVRVEIVDCPDLTKEPFTLACKGLGGKPRLVEIGGPPYLLPLVRREKLYNMSDIGKLTDVEPTFLIGAGAGPWPYAGVNCEMMVNLEVKG--GKVNNHTRISKINIKDGSCILERLPDT--ETRCALLANIFCSEGKPGKVLQVSCKKRIGNDDFIASIRKSLQAHYKEKAVGLGGTFLLKEGKAKQHIMP-EFSVTPINTDEEVEKWLHFYNMSAPLIAVGTLASADPGLDLRLQHFHSFSHHGEGGHYHIDTEPDNVEYLGYFALGEYVYRIDQPTDTHHVGRD +> +-AEYSFHVPSLEELVGVLRKGLTDNFADVQVSVVDCPNLTKEPFTFPVKGIYGKTRIAEVGGVTYLLPLINKKKVYDLNKITKEIQLPGAFVLGAGAGPFPTLGFNSEFMPVVQTESEHKPPVNGSYFAHVKSADGGCLLEKYSEKYHDLGFALLANLFASEGQPGKVMEVKCKRRPGKLNFVTCTRQTLEKHYGDKPVGMGGTFVIQKGKVKTHIMPAEFSSCPLNSDEDVNKWLRFYEMKAPLVCLPVFISRDPGFDLRLEHTHCFSHHGEGGHYHYDTTPDIVEYLGYFLPAEFLYRIDQPTETHSFGQD +> +-ESCALHLPALEEIAAVLESGLKKNYEDVQVEVVDCPDLTQEPFEFPVKGLCGKSRIADVGGVPYLVPTARPDKIYDINTVAKQIDLPGAYILGAGAVSHRSVGMNAELIFSVQAESSSSPAVNGNYMASVNPADNSCLLEKYQDKHKDNAFGLLSNLYASEGKPGKVIQVKAKRRTGKENFVSCMRKSLREHYGDKAVGMGGTFVIQEGKAKLHVMPREFSACPLNTDEDVDRWLNYYEMRAPLICQSVFVSHDPGFDLRVEHTHCFSHHGEGGHYHTDTTPDTVQYLGYFHPAEYLYRIDRPAVTHMVGRD +> +IKEKPFHKPPLTEVADVLSRGLTATFEAVSVAVVECPDLTRPPFNLTTQGLCGDPKLVELGGPPYLVPLVQRDKLYDLAALTRHLHRDPANLVGAGAGPWPHIGVNCEGIIDLSVRN--GSVSQGTRIVSVEPVSSGYLQRRLPPT--ETRTALLGNYLLSEGRPGKVLKVVAKKRIGESNFITAIRETLKNHYGDKVVGLGGTFLLREGRVKYHVMP-DFSTTALCSDADVDGWLHYFEMKAPLVQLGTLVTGDLDLDLRVQHFHGWSEHGDGGHYHHDTTPAAAHYEGYFTLAGSVLRIDPPADTHGLGRD +> +-KKADLHVPTLEEAAKVLEKGLKNNFENVSVSVVDCPDLTQKPFNLSSPGICGNERLADVGGPPYLVPQYNKDKIYDVGKVSEEVGLPGAFVIGAGAGPWPLVGVNSEMICNVKLGKNGQPTVNNTYIAKVGEKDGKCQQMQI-KD--STEFCLMANLLCSEGKQGKVLQVKASKRTGPENFMSSLRKTLDSHYENKSVALGGVFLVETGKATLHIMP-DFSKVPLKSDGEVDEWLQYFEMDAPLVCLGELVSRDVNLDLRTEHFHCFSDHGQGGHYHYDTTPDTVSYRGYFTIPHSVYRLDQPKSN------ +> +IEKKSLDRPPLEELAKVLNKGLQSNFEHVTVEVVDCPDLTQQPFTLAKKGLGGSPKLVEVGGVPYLLPLVKREKVYDLKKIATMIGSDPAFIIGAGAGPHPYAGVNCEGILNMNIAK--GVVDQQTRISKVNPSNEEVPIQEILPN-NETRVALLANLFFSSGEPGKVLKIHAKKRTGPLDFIASIRQTLVNEYKNKVVGLGGAFLLKEGKAKQHVMR-DFSKTPINTDEELNNWLKFYNMRAPLVAVGTLINNDHGLDLRVQHFHSFSHHGEAGHYHIDVTPETAEYLGYFNTGEEIYRVDRPVETHQFGRD +> +VEKFALHVPSLEELSGVLQNGLTENFADVQVSVVECPDLTHDPFNFPVKGICGKPRIADVGGVPYLVPLVQKDKVYDLNTVAKQIELPGAFILGAGAGSSRILGVNAEFIPVVQAESEQKPAVNASYTAQINPADGGCLLEKYSKKYSDCEFGLLANLYASQGQPGKVIEVRANGRTGQHNFVTCMRQIIEKCYGDKPVGIGGTFVIQKGKAKIHIMPPEFSACPLNTDEEVNNWLNFFEMKAPLICQPVLISRDPGFDLRVEHTHCFSHHGEGGHYHNDTTPDSVQYLGYFLPAELLFRIDRPKESHMVGRD +> +-VKHNLHKPNLNEVAKVLQAGLSNTFSHISVDVVDCPDLKGKPYMLAAEGICGNPCLADVGGVPYLIPVARADKVYNLREIAKQIELPNALIIGAGAGPRHHVGTNCEMMPNIKFNEN---EFNNTHIAKIGKDG-NCELVHL-KD--SEEFCLLGNLFASEGKSGKVIKVTAQHRMTSENFVSVMRKTLAEHYKDQPVGIGGVFNIQVGKAKLHIMP-DYSKTPLKTDEDVNNWLKFYNQPAPLICLSTFISHDPGLDLRVEHTHCFSDHDVGGHYHEDTTPDIVKYEGYFNVADFIYRIDPPAETHQVGRD +> +--RRALHIPPLEEIRDILREALPANFAEVTVDVVDCPDLTQQPFTLAEAGLGGGTKLLEIGGPPYLLPLVNRDKVYDVKSICQNVNHNGKFVVGAGAGPWPLVNTNCELIMNVSISPAESSTKNATHICMVDKDNGKCIDQTLSSS--ETRFALLANLFVSEGKPGKVIKVHAKKRTGSNDFIASIRKALAARYTNQLVGLGGTFLLKEGKANQHIMP-DFSKVPLTSDDDLNKWLRFYEMSAPLVAVGTLVTAETDLDLRVQHFHSFSHHGEGGHYHYDTTPDTVEYLGYFNVGEAVYRIDKPPMAQAFGKD +> +-VKKNLYVPSLDEIKDVLKEGLVKNFLDVEVEVVDCPDLTQEPFTLAAPGLCGNPTLLEIGGPSYLLPTVQKNKLYDVQQLLNHLQYKTDFVIGAGAGPWPYINSNCELIMNMTFSP---NVQNGTRISSVSKANGKCVLQNLPNS--ETRFALLANLFVTEGKPGKVLKVHVKKRTGNNDFIASMQKAIAQHYQNNLVGLGGTFLIKDGKVKQHVMP-DFSVTPLNTEAQLNKWLHFYNMSTPLIAVGTFVSSESDLDLRVQHFHSFSHHGEGGHYHIDTTPETIEYLGYFNLGTTLYRVDKPLTGVQFGKD +> +ITKKQLHVPSLDEVKEVLKEGLLTNFAEFQVEVVDCPNLMQEPFTLAAPGLGGNPTLLEIGGPPFLLPMVQRNKVYDIRQLLNHLQYNKDFVVGAGAGPWPYANTNCELMMNVAISS--SNVTNGTRISSVDKTNGNCVLQTLPNE--ETRCALLANLFVSEGKPGKVLQVRAKKRTGNDDFIACMQKAIAQHYQNDLVGLGGTFLMKDGKIKQHIMP-DFSATPLNTEAQLNNWLNFFNMSTPLIAVGTFVSSESDVDLRVQHFHSFSHHGEGGHYHIDTTPETIEYLGYFNLGTTLYRIDQPTTKVQFGKD +> +VEKFAFHVPSLEELAGVLQKGLKENFADALVSVVDCPDLTQEPFTFPVKGICGKPRIADVGGVPHLLPLVQKDKVYDLNTVAKEIELPGAFILGAGAASSRILGVNAELIPIAQTETEQKHAVNASYTARINPTDGGCLLEKY--K--YSGFGLLANLFASQGQPGKVIEVKANGRTGQHNFITCLRHILEKHYGDKPVGMGGTFLIQKGKAKMHIMPPEFSACPLNTDEEVNNWLKFFEMKAPLVCQPVIVSRDPGFDLRLEHTHGFSHYGEGGHYHNDTTPDSVEYLGYFMPAELLFRIDRPKETHLIGRD +> +---------------EVLHKGLKSNFAEVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLMPIVNKKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFIPLVQTESENHAPVNGSYFARINPADGGCMLEKYSQKYRDFGCALLANLFASEGQPGKVIEVKAKRRTGQLNFVTCMRQTLEKHYGNQPVGMGGTFIVQKGKVKAHIMPADFSSCPLNSDEEVNKWLSFYEMTAPLVCLPVFVSRDPGFDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAQLLYRIDQPKETHLFGRD +> +-ESKELLLPPLAELSQVLKDGLSKNFSNVEVNVVDCPDLREKPWTLAAPGICGRPRIADIGGPPYLIPLPDLSKLYSFDDIANSVELPGGFIIGAGAGSSKFVGVNCEMMTNLVTSS-EQKGVIATKIAKVSKEDGSCVLENY--N--CGEFSLLGNFLVSDGHPGKVLKVCASRRTGNENFITCMRHALARYYGDSPVGLGGVFVLEKGKAKIHVMP-SFSETPLKTDEDVNNWLKFYEMSAPLVCVGVFESHDPGLDLRIEHFHCFSAHGEGGHYHYDVTPDDVHYTGFFSLAERVYRIDRPLATHNVGRD +> +ITKRDLHTPSLDEIKDVLKEGLAKNFVEVQVEVVDCPDLTQQPFTLAAPGLNGNPVLLEVGGPSYLLPIVQKNKLYDIQQLLNHLQYNKDFVVGAGAGPWPHINSNCELMMNMTISP--SNVQNGTRIASVNKENGNCVLQNLPNS--ETRFALLANLFVTEGKPGKVLKVHAKKRTGNNDFIASMQKAIAQQYQNNLVGLGGTFLMKDGKVKQHVMA-DFSAIPLNTETQLNNWLNFFNMSTPLVAVGTFVSSESDLDLRVQHFHSFSHHGEGGHYHIDTTPETIEYLGYFNLGTTLYRVDKPSTLLQFGKD +> +-----LHVPPLQEICQVLQNGLRNHFEEVEVTSTRCPNLQKKPFLLAAEGLSGSPRLADVGGVPNLIPLVQKDKVYNFPEVAKQIDLPDAFIIGAGAGPCHYIGVNSELMPNIKNGK---SVINKTHFAKVAEDG-SCDLQLI-KD--NTEFCLMGNLFASEGKPGEVLKIFARKRIGSDNFVTAMRKILANHYKEKSVGMGGVFLINKGKAKLHVMP-DFSTKPLNTDEDVDNWLKFYNMNAPLICLSTFISFDPGLDLRVEHTHCFSEHGEGGHYHTDTTPEEAEYLAYYNIAEYIYRIDPPSQTHSVGR- +> +-ESRDLLLPPLEELVQVLKAGLAKNFSNVEVEVVDCPDLRVKPWKLAAPGICGRTRIADVGGPPYLIPLPNLSKLYSFDDVASNVDLPGGFVIGAGAGSSKFVGVNCEMMANLVTNS-EQKGVIATKIAKVNEVNGACVLEEY--N--CREFGLLGNFLISDGSPGKVLKVCASKRTGDENFITCMRHTLAGHYGNRPVGVGGVFVIEKGKAKIHVMP-KFSETPLKTDTDVNNWLKFYNMSAPLVCVGVFESHDPGLDLRIEHFHCFSDHGEGGHYHYDVTPVDVQYTGFFSLAEKVYRIDRPQTTHNVGRD +> +VKKVTLQKPSLEEVAKILNDGLGKHFEHASVSVVDCPDLTQSPFHLAAPGLGGQTAIADVGGPPYLVPLVQRDKKYSFEQVASLVADKNAFLIGASAGPFHLVGQNCELMPNVLLKRVFEVVENNTHFSKVNEKD-EYSLSKI--S--ASEFGLLGNMFVSEGKPCKVLKVEARKRTGADNFVTAMRNVLREHYQQTPVSLGGSFLVATGKAKLHIMP-DFSTKPLLSDDDVNNWLRFFEMDSPLVCLSVFHSLDPQLDLRIEHTHCFSDHNQGGHYHYDTTPQDVSYLGYFNLASAIVRIDAPKETHGIGRD +> +-NKIPTLVPSLDEVVSVLDDGLKKNFSNVSVSVVDCPDLTQKPFKLASPGLCGNARLADVGGPGFLLPLPQKDKKFRYSQIAESVELPGAFMIGAGAGPCHIVGVNSELIKNVKMDGAGGVTKINSHIAKVNPQDGGCILETI--D--KPEFSLMGNFLCSDGQPGKVLEVKASCRTGEENLMSCLRKALQARYGEKPVALGGVFLVEKGKANLHIMP-EFSDTVLDSQEKVNNWLKFYEMDAVLVCVGELVSHDPGYDLRVEHFHCFSDHGQGGHYHFDVTPKDVEYRGYFVLAESIYRIDQPVKTTQLGR- +> +-VKKELHVPTLEEVKNVFLKALKENFKDVEISVVDCPDLTEEPFTLSAPGLGGRMNIVEVGGPPYLLPLVNREKVYDLQSLLKDLKYGDRFAAGAGAGPWPYINQNCEMMMNVMIDS--SKIKNGTRIASVKNDDQTCLLEVLKGN--ETRFALLANLFLCEGIPGRVLKVHVKTRVGKKDFIATMQQALAEHYVDNLVGLGGTFVIKQGKAKQHVMP-DFSKTPLNTVEDLDKWLHFYEMSAPLVAVGTFVSAETDLDLRVQHFHSFSHHGEGGHYHIDTTPNDVEYLGYFNVGEVLYRVDQPPNPLQFGKD +> +-ENCSFHVPSLEEICSVLKSGLLKNFADVSVIVTECPDLSKEPFEFPVKGLCGKSRIADVGGVPYLVPKPRLDKVYNVNAVAKKIGLPGAYILGAGATSHKSLGMNAELIFSVQAENESIQAVNKSYVASVNPGDGSCLLEKYRDRNNDNDFGLLSNLYACEGKPGKVIEVSVKRRIGQDNFVSCMRKSLKTHYGEKAVGLGGTFLLKEGKAKLHVMPREYSACPLNTDEDVNGWLKFYEMKAPLICQSVFVSHDPGYDLRLEHTHCFSHHGEGGHYHYDTTPDTVEYLGYFHPAELLYRIDKPSATHMVGRD +> +VEKFSLHVVGLEELCEVLQDGLKTNFAEVQVTVVDCPDLTKEPFTFAAPGICGNPRLADVGGVPYLIPVPQTQKVYNLNAVAQDVQLPGAFIIGAGAVSSKAVGMNGEFMPNIITEKDGKPAVSHSYCATINPANGKCVLEKYTETYKTMDFEMLANLYISEGQPGKVIEVKATRRTGESDFVKCMREALGYRYGDKPVGMGGVFIIQKGKAKLHVMP-AFSSTPLESDREVTKWLKFFDMNSPLICQSTFVSHDPGLELRVEHTHCFSQHGEGGHYHYDTTPNIIQYLGYFLPAEHLYRIDRPNKSAS---- +> +-EKVELHAPELEELRAVLQSGLEANFAEVQVSVVDCPDLTKEPFQFPVKGLCGNPRITDVGGVPYVVPLVKKEKEYNMNTISKELELPGAFILGAAAAPSRIVGMNAELMPLVLTEAQGRSAVNSSYFSSINPADGQCLLEKYSDKFSDCNFALLGNLYACEGKPGKVIEVRAKKRTGTHSLVTALRTTLEGHYPDKSLALGGTFIIQKGKAKIHIMPREFSACPLNTNDDVNNWLKHFEFSAPLICQSVLVSRDPGLDLRMEHTHCFSHHGEGGHYYIDTTPDSVEYLGYFMPAQFVYRIDRPKETHKFGRD +> +-ESRDLLQPPLEELVQVLKHGLSQNFSNVEVEVVDCPDLREKPWTLAAPGICGRARIADVGGVPYLIPLPNLSKLYSFDDVAKNSDLPGGFVIGAGAGSSDFVGVNCEMMANLVTNS-EQKGIIATKIAKVNEENGSFVLEDY--N--CGEFNLLGNFLVSEGKPGKVLKICVSKRTGVENFVSCMRNTLAGRYGDQPVGMGGVFVIEKGKAKIHVMP-RFSKTPLNTDADVNNWLKFYEMSAPLVCVGVLESYDPGLDLRIEHFHCFSDHGEGGHYHYDVTPDDVQYTGFFNFAEKIVRIDRPLTTHNVGRD +> +-VKKELHVPPLDEIKDVLKEGLARNFFDVQVEVVDCPDLTQEPFTLAAPGLGGNPTVLEIGGPSFLLPLVHRNKLYDVQQLLKHLQCCKNFVIGAGAGPWPHLNCNCELMMNMIVSP--TGVKSGTHIASVDKTNGNCVLENLPNN--ETRLAILANLYVSDGKPGQVLKVHAKKRTGNDDFIACMQKAMAQHYEKNLVGLGGTFLMKDGKIKQHVMA-DFSTTPLNTEKELNNWLHFYNMSTPLVAVGTFVSSESDVDLRVQHFHSFSHHGEGGHYHIDTTPETIEYLGYFNLGSVLYRIDQPTSKLQFGKD +> +-EKFELHVPKLEELCEVLQDGLKKNFADMKVSVVDCPDLSEDPFRFPVKGLCGKPRITDVGGVPYLVPLVQLDKVYNMNTVAKEVELPGAFILGAGAVSSKAVGMNAELMPLVLTESGGKPAVNSSYLSSINPGEGTCLLEKYSDKYSDCDFGLLANLYACEGKPGKVLEVKASRRTGGDSLVTCLRKTLANHYSDKSLALGGTFVIQKGKAKIHIMPREFSACPLSSDEDVNEWLKHFEVSAPLVCQSVLVSRDPGLDLRVEHTHCFSHHGEGGHYYIDTTPDTVEYLGYFLPAEFIYRVDRPKTTHVIGRD +> +-THRPLHVPGLNEIKTVLEEGLSTNFAEVKVEIVNCPDLTKEPFLLSASGLSGNPTVLEIGGPSYLLPIVQRDKLYNIHELLQHMNYSDKFVIGAGAGPWPYINSNCELMMNLVISS--SGIKNETRIASVDKSSGNCKLETLNRN--ETRLAILANLFVSKGETGSVLKVHVKRRTGKDDFIACMQKALAHHYKDKLVGLGGTFLINEGKVKQHVMP-DFSTTPLDTLQQLDDWLKFYNMSTPLVAVGTFVSSETDLDLRVQHFHSFSNHGEGGHYHIDTTPETIEYLGYFNLGNNLYRIDQPAKSLKFGKD +> +VEKKELHVPDYNEVVKVLQDGLKANFSEVSVGVVDCPDLTKEPFTLAAPGLCGRPRMADIGGVPYLMPLVQRHKKYNFQDIAEKIELPGAFLIGAGAGPLHVVGTNSEMMTNINLNN----GDNSTYTCKMHTEDNSYILEKG--L--SLDCSLLANIYASDGKPGKVIEVKASTRTGPENFVTCMRKALKEKYGDKPVGMGGTFIIEKGKAKIHIMP-DFSEVPLDSNEKVDQWLKFFDMKAILVCLSVFISHDPGLDLRVEHTHCFNKHGGGGHYHYDVTPDDVVYHGYFVPSEYMYRIDAPTETHMIGRD +> +-EKVQLHVPDLEELRGVLQAGLEDNFAEVQVSVVECPDLTKEPFQFPVKGLCGKPRITDVGGVPYLVPLVQKHKEYNMNTISKELELPGAFVLGAAAAPSRVVGMNAELMPLVLTEAEGRPAVNSSYFASINPADGQCLQEKYSNKFSDCNFGLLGNLYACEGKSGKVIEVKAKKRTGDHSLVAAMRNTLESHYPEKSLALGGTFIIQKGKAKIHIMPREFSACPLDTNDDVNNWLKHFEVRAPLICQSVLVSRDPGLDLRVEHTHCFSHHGEGGHYYIDTTPDSVEYLGYFMPAEFVYRIDRPKDTHEVGRD +> +-EKVQLHAPDLEELRGVLQAGLESNFAEVRVSVAECPDLSKEPFQFPVKGLCGSPRITDVGGVPYLVPLVQKDKEYDMNTISKKVELPGAFLLGAGAAPCRIIGMNAELMPLVLTEAEGRPAVNSSYFSSINPADGQCLLEKYSQKFSDCNFGLLGNLYACEGKPGKVIEVQAKKRTGSHSLVTALRKTLEAHYPDKSLALGGTFIIKKGKAKIHIMPREFSACPLNTNDDVNKWLKHFEVNAPLICQSVLVSRDPGLDLRVEHTHCFSHHGEGGHYYIDTTPDSVEYLGYFLPAEFVYRIDRPTQTHTVGRD +> +-EKYQIHVPSLEELSEVLEKGLRNNFEDAKVCVAECPDLSQAPFQFPVKGLCGKPRITDVGGVPYLIPLVHKDKVYNMNTVSKELELPGAFILGAGAVSFKTVGMNGELMPLVLTESEDKPAVNGSYFSSINPVDGKCLQEKYSERFSDCDFGLLANLFACEGKPGKVIEVRASRRKGEESLVSCMRKTMEEHYGDKTVALGGTFIIQKGKAKIHIMPQEFSSCPLNTNEDVNNWLKHFEVSAPLICQSVMVSRDPGLDLRLEHTHGFSHHGEGGHYYIDTTPNTVEYLGYFLPADFIYRIDRPTDTHNVGRD +> +-VKRNLHVPSLDEIKDVLKEGLIKNFANVEVEIVDCPDLTQEPFTLSAPGLSGNSTVLEIGGPSFLLPTVQKNKLYDIQQLLNHLHYKEDFVIGAGAGPWPHINSNCELIMNMVVSL--SNVQNGTHISYVNKGNGNCELQNLPNN--ETRFALLANLFVTEGKPGKVLKIHVKKRVGNDDFIACMQKAIAQNYHNNLVGLGGTFLIKNGKVKQHVMP-DFSATPLRTEAQLNNWLHFYNMSTPLIAVGTFVSSESDLDLRVQHFHSFSHHGEGGHYHIDTTPETIEYLGYFNLGTTLYRIDKPLTGVEFGKD +> +-QKTRLYTPSLEEVAQVLQEGLSKNYSTVQASVTECPDLTKKPFMLAGEGLCGNPRLADIGGVPNLIPLAKREKIYNFEKIAGQLDLSNAFMIGAGCGPAHVMKVNTEMMPNLSVDGGDGKVNNQTYLGRLNPDEKSYDLFVS--P--TTDFNLMANVFCSEGKPGKVIEVKVQKRVGEENFMSCMRKVLAAHYGTKPVALGGVFLVEKGKVKIHIMR-DFSKVPLNSDEEVNKWLTFHEASAPLVVIGELISHDPDLDLRVEHFHLFSDHGEGGHYHTDTTPDIIEYRAYLNVAEFMYRIDRPTETHNIGRD +> +-VEKELYQPPLDEVVQVLSNALRQNFEHVEVSVVECPDLTKPPYYLTASGLSGNPKLVEVGGVPYLLPLVNRDKVYDLKGLVEHLRRGDSYVAGAGAGPWPYAGVNCEGIVNLMVKN--GTVSQGSRIVTVEPRSSGYLQRQLPDT--ETRSALLGNYLVTDGNPGKVIKVEVKGRTGADNYITAIREGLKKYYKDKVVGLGGMFLLKNGSVKFHVMP-EFSTKPLCSDSDVDEWLHYFEMSAPITVLGTLVTGDMGLDLRVQHFHGFSAHGDGGHYHYDTSPARAHYEGYFVLGAALVRVDAPTDTHDFGRD +> +IEKRELHVPSLDEVKNVFIDALRENFAEAEIEVVDCPDLTQEPFTLSAPGLGGRVNILEIGGPPFLLPTVQRDKVYDIQSLLKDLKYGDRFVAGAGAGPWPYLGTNCEMMMNVMMDS--AKLKNGTRIASVEKSEGSCVLETLKGN--ETRFSLLANLFLCEGIPGKVLKVHAKQRIGNKDFIATMQQALAEHYRDKLVGLGGTFVMMEGKAKQHVMP-DFSETPLDSVKQLDHWLKFYDMSAPLIAVGTFVSAETELDLRVQHFHSFSHHGEGGHYHIDTTPNDVEYLGYFNLSEVLYRIDQPPNTLQFGKD +> +-ECKPLHVPPLEEIADVLNKGLKKHFQDVKVEVVNCPDLTQMPFTLANKGLNGNTHMMDVGGPPYLVPFVQYDKVYDLCDIPDVVKMKSAFIIGAGAGPHPYATVNCEAIMNINIEN--SLVKQQTRIVKVNQTDGTPVQEQLPTT--ETRFALLGNFFICEGKPGQVLQVHVKKRVGCMDFIASIRGVLADHYGNRILGLGGTFLLREGKAKQHVMP-HFSETAINSDDEINQWLKFYEMSAPLIANGTLITGDYDLDLRVQHFHSFSYHGEGGHYHIDTTPDTVEYLGYFNLAQDIYRVDKPEHTHKVGRD +> +--RRALHVPSLEEIKDVLAQALPGNFAESTVEVVDCPDLTQQPFTLAAPGLGGGTKLLEVGGPPFLTPLVNREKVYDVKTLCQNVNHSGRFVIGAGAGPWPHFNSNCELIMNISISP--SEVKNETRIALVDQVDGKCVQQSLPKT--ETRFALLSNLFLSEGKPGKVIKVHAKKRTGKDNFITTIRKALAARYTKQLVGLGGTFLLKEGKAHQHIMP-DFSITPLTNDADMNKWLNFYDMSAPLIMVGTLVTSETDLDLRVQHFHSFSHHGEAGHYHDDTTPDTVEYLGYFNVGEALYRIDQPPVALGYG-- +> +-EKFELFVPKLEELSEVLQNGLKENFADVHVSVVECPDLSQDPFRFPAKGICGKPRITDVGGVPYLIPVAQLDKVYDMDTVAKEVELPGAFILGAGATSSKSVGMNAELIPLVRTENDGMSAVNGSYYASINPVDDKCLLEKYSDKFKDFGFGLLANLYACEGKSGKVIEVKASRRTGAISLVTSMRKTLEIHYNDKYIAMGGTFVIQKGKAKTHVMPREFSACPLRTGEEVNKWLKHFEMSAPLICQSVLVSQDPGLDLRLEHTHCFSHHGEGGHYYTDTTPDTVEYLGYFLPAEFVYRIDRPKITHDIGRD +> +-EKFQLYVPNLEELCDVLQRGLKNNFADAQVCVVDCPDLTQDPFKFPVKGLCGKPRITDVGGVPYLVPLVKVDKEYNMNTVSKELELPGAFILGAGAVSSKNVGMNAEMMPLVLTEAEGRPAVNSSWLSSINPDNNQCLLEKYSDKFSDCDFGLLANLYACEGKPGKVIEVRAKRRIGEESLVGALRKTMEEHYPDKSLALGGTFLIQKGKAKIHIMPREFSTCPLNSNDDVNKWLKHFEVSAPLICQSVMVSRDPGLDLRVEHTHCFSHHGEGGHYYIDTTPDTVEYLGYFMPAEFVYRIDRPSETHEVGRD +> +-ERVQLHAPHLEELRGVLQAGLQENFAEVQVSVVECPDLTKEPFHFPVKGLCGSPRITDVGGVPYLVPLVQKHKEYNMNSISKELELPGAFILGAAAVPSRIVGMNAELMPAILTEAEGRPAVNSSYFSSINPADGQCLQEKYSDKFSDCNFGLLGNLYACEGQPGKVIEVRAKKRTGDHSLVTALRTTLEGHYPNKSLALGGTFIIQKGKAKIHIMPREFSVCPLNSNDEVNNWLKHFEVSAPLICQSVLVSKDPGLDLRVEHTHCFSHHGEGGHYYIDTTPDSVEYLGYFMPAEFVYRIDRPTETHRVGRD +> +VEKKSLYVPPLQEIADALNKGLTTNFAEVNVEVVDSPDLTQKPFSLASKGLGGNPKIVEIGGPPYLLPIVDRKKVYDLKDIANLINSNPAFIIGAGAGPHPYIGVNCEGILNLNIVN--GSVEQHSRISKVDQNDENSIQEILPNS--ESRIALLANLLFSEGKPGKVLKVHVKKRIGPKDFIASIRTVLEEVYKGKLVGLGGAFLIKEGKVKQHVMR-DFSKTPLENEEDLNNWLKFYNMSAPLVALGTLVNGDGGLDLRVQHFHSFSHHGEAGHYHYDTTPETVEYLGYFITGDEIYRIDKPVATHTWGRD +> +VEKFTFHFPALEELCQVLEKGLKENFAAVEVSVVDCPDLTQDPFGFPVKGICGKPRISDVGGVPYLVPVVHLDKVYDLNTVAKDMELPGAFILGAGAVSSRRVGVNAELMPLVQTEGESKPAVNGSYSARINPANGACLLEKY--S--DCELGLLGNLYACEGKPGKVVRVKASKRTGQVSLVTAMRKSLENHYGDKPVGMGGTFVIQKGKAKIHIMPAEFSSCPLNSEEDVSKWLKYFEFTAPLICQTVFVSRDPGFDLRVEHTHCFSHHGEGGHYYTDTTPDTVEYCGYFLPAELLYRIDRPKETHTIGR- +> +-QKASTHVPSLDEVAKALSGGLSQNFANVSTSVVDCPDLTKKPFMLVSEGLGGNPRLADVGGPGFLTPTPQTDKKFTFAQIAKLAELPGAFMIGAGAGPCQHVGCNSELMNNILLDSNGGVVRNNAHIAKVNPENNACVLEKL--S--CPEFNLMGNFLISEGKSGKVLEVKAGKRTGEENFVSCMRKTLKSYYGDKIVALGGVFLIEKGKANLHIMP-DFAKEPLHTNEEVKNWLKFYDMSAPLVCVGELVSHDPGMDLRVEHFHCFSEHGEGGHYHWDTTPEDVQYRGYFVLADYIYRVDQPPNITDL--- +> +--ERQLYTPRLEEIVEVLRQALGANFSEVDVSVVECPDLTQEPFTLAGKGLNGNPKILEIGGPAFLLPNVQREKVYDIQPLLKTISKSNALIIGAGAGPWPYLNKNCELMMNLSISS--SIVKNQTRLASVNTVNDCCILQTVDNK--ETRFALLANLFVSEGIPGKVLKVHVKKRIGDKDFVASIRTALADHYKDKLIGLGGTFIIKEGKAKQHVMQ-DFSKTPLNNEEELNNWLRFFNMSAPLIAVGTLVTAETDLDLRVQHFHSFSHHGEGGHYHIDTTPETVEYLGYFNTGNTLYRIDKPIISHTFGKD +> +--KRELHVPTLDEVKNVFIKALKANFEEVEVEVIDCPDLTEEPFTLAAPGLGGRLTIVDVGGPPYLLPLAQKDKIYDIQPLLKELKYGDRFVAGAGAGPWPYLNSNCELMMNVMINS--NKIKNATHIASVDKNNETCVLETLKGN--ETRFAVLANLFLCEGIPGKVLKVHVKKRIGKRDFINTMQQALTEHYTDKLVGLGGSFVIKEGKVKQHVMP-DFSDKPLNNLQELNNWLHFYDMTAPLIAVGTFISAETDLDLRVQHFHSFSHHGEGGHYHIDTTPDTVEYLGYFNLGETLYKVDQPTVALQFGKD +> +IEEKPLYTPSLEEVADVLSEGLRKTFEIVNVTVEDCPDLTREPFDLTTPGLSGDSKLVELGGPPYLTPRVRRDKVYDLAALLRHLGRDPALLAGAGAGPWPYLGVNCEGIINLSVRE--GAVTQGTRVVSVSPSQASYLQRRLPPG--ETRTALLGNYLLSEGRPGRVLKVVAEKRIGPSNFITAIRETLKERYGDRAVGLGGAFLLAAGKVKHHVMP-DFSASPLCSDEDVDRWLHYFEMTAPIMHLGTLVTGDLGLDLRVQHFHGYSAHGDGGHYHYDTTPLQVRYEGYFTLASSVIRVDRPSETHGIGRD +> +VEKFALHIPTLEELVGVLQNGLKENFADVEVSVVDCPDLTQEPFKFPVKGICGNPRIADVGGVPYLLPLVQKDKVYDLNTVAKEIQLPGAFFLGAGAVSSRVVGGNAELIPIVQAQSGKSPAVNGSYLARINPEDGGCLLEKYSSKYKDCEFGLLANLYASEGLPGKVIKVKANRRTGDQNFISCIRKTLEKCYGDKPVGMGGTFVIQKGKAKFHVMPSEFSECPLKTDAEVNNWLKFFEMKAPLICQPVLVSTDPGVDLRLEHTHGFSHHGEGGHYHEDTTPETVEYLGYFVPAEFLFRIDRPKHTHLVGRD +> +-EKKKLHCPALEELCNVLESGLNKNFADVQVGVVDCPDLTKEPFQFPVKGLCGNPRITDVGGVPYLVPLVQRHKEYDMNTVSKEVELPGAFILGAAAAPSRVVGMNAEFMPLVKTETEGRPAVNGSYFSSINPADGKCLQEKYSDTFPGCQFGLMGNLYACEGKPGKVIEVRVKKRTGEDSLVTAMRKTLEAHYPDKNLALGGTFIIQKGKAKIHIMR-EFSVCPLNTDDEVNNWLKHYEIDAPIISLSVFVSKDPGLDLRVEHTHCFSHHGEGGHYYIDTTPDTVEYMGYFLPAEYLYRIDRPQESHAIGRD +> +-EKFQLHVPNLEELCQVLESGLNKNFSDVKVSVTDCPDLTQQPFGFPVKGLCGKPRITDVGGVPNLIPLVKLDKVYNMNSVSKEVELPGAFILGAGAISFKTAGINGELMPLVLTEAEGRSAVNASYFSSINPEDGKCLQEKYSDRFDDCDFGLLANLYACEGKPGKVIEVKACRRTGEDSLVSCMRKTMAEHYGEKSVALGGTFIIQKGKAKIHIMPREFSVCPLNTDEDVNNWLRHFEVSAPLIFQTVMISRDPGLDLRVEHTHGFSHHGEGGHYYTDTTPNTVEYLGYFLPAETVYRIDRPTETHNVGRD +> +IKEKELYTPPLDEVACVLSNGLTTNFKFVEVSVADSPDLTEPPYYLKSPGLTGDAKLVEIGGPPYLVPQVKRDKIYDLAKLLEHLNRDPAFLAGAGAGPWPYLGVNCEGIVNLSVRN--GTVDQGTRIVSVHPVSSGYLQQQLPND--ETRTALLGNYLLTEGKPGKVIKVVAKNRTGKSNFITSIRETLKTHYGDKVVGLGGAFVLRAGRGYFHVMP-DFSRAPLCSDAAVDSWLHYFELDAPLTVVGTLVTGDLGLDLRVQHFHGFSGAGAGGHYHYDTTPEDVHYEGYFTVASSLIRVDPPVETHTFGRD +> +-EKVQLXSPSLEELQGALQAGLESNFAEVQVSVVECPDLTKEPFNFPVKGLCGNPRITDVGGVPYLVPLVKKNKEYNMNAVSKELELPGAFILGAAAAPSRVIGMNAELMPLVLTEAEGRPAVNCSYFASINPADGQCLQEKYADRFSDCSFGLLGNLYACEGKPGKVIEVRAKRRTGSDSLITALRTTLEAHYPGESLALGGTFLIQKGKAKIHIMPREFSACPLNTNDDVNNWLKHFEVSSPLICQSVLVSRDPGLDLRMEHTHCFSHHGEGGHYYIDTTPDTVEYLGYFLPAEFVYRIDRPKEMHRVGQD +> +--KFQLHVPDLEELCQVLEKGLRKNFEEVKVCVSECPDLTQEPFKFPVKGLCGNPRITDVGGVPYLIPLVQVDKVYNMNTLAKELELPGAFILGAGAVSSKTVGMNAELMPLVLTEHEGKPAVNASYFSSVNPADGKCLQEKYSDRFCDCDFGLLANLYACEGQPGKVMEVRASRRTGEDSLVSCMRKTMAEHYGDKSIALGGTFIIQKGKAKIHIMPREFSSCPLNTNEDVNNWLKHFEVSAPLICQSVMVSKDPGLDLRVEHTHGFSHHGEGGHYYIDTTPSTVEYLGYFLPAEFVYRIDRPVETHNVGRD +> +--RRDLFVPSLDEIRDVLKEGLVKNFGEVEVEIVDCPDLTQEPFTLAASGLNGSPTVLEIGGPSFLLPMVQREKVYDVQQLLNHLQYGKDLVIGAGAGPWPYLKSNCELMTNMVVSQ--SNVRNETRIASVNKTNGNCVLGTLPSS--ETRLALLANLFVSEGKPGKVLKVHAKKRTGNDDFIASMQKAIAQRYQDNLVGLGGTFLMKDGKIKQHVMP-DFSTTPLNTEAKLNKWLQFYNMSTPLIAVGTFVSSETDLDLRVQHFHSFSHHGEGGHYHIDTTPETIEYLGYFNLGTTLYRIDKPATGVQFGKD +> +-EKFQLHVPTLEELCQVLEKGLRKNFEEAKVCVAECPDLTQEPFQFPVKGLCGKPRITDVGGVPYLVPVVHMDKVYNMNTVSKELELPGAFILGAGAVSSKAVGMNAELMPLVLTELDSRSAINASYMSSINPVDGKCLQEKYSDRFHDCDFGILANLYACEGKPGKVIEVKASRRTGDESLVSCMRKTMEEHYGDKALALGGTFIIQKGKAKIHIMPREFSSCPLNTDEDVNNWLKHFEVSAPLICQSVMVSRDPGLDLRLEHTHGFSHHGEGGHYYIDTTPNTVEYLGYFLPAEFIYRIDRPTETHTVGR- +> +VEKRPLYVPPLNELVDVLNKSLKNNFQEVQVELVDCPDLTKQPFTLASEGLSGNETLVEIGGPPFLAPLVQRDKVYDLKDIAKLVDSEPAFIIGAGAGPHPYVGKNCEGIYNLKIEN--GKVDQQTRISKTDDKDDKSIQEQLPNS--ESRVALLANLFFSEGKPGKVLKVYARKRIGNDDFIASIRKSLKDGFKDRLVGLGGAFVMKTGKAKQHVMP-DFSKTPLKSDDDINNWLNFYTMSAPLIALGTLVNGEGELDLRVQHFHSFSHHGEAGHYHIDTTPDIVEYLGYFKPGQTIYRIDKPVDSHKFGRD +> +IEKRELHVPTLEEVKNVFLKALKENFEEAEVEVVDCPDLTEEPFTLAAPGLGGRLNIIEVGGPSFLLPSVQKDKVYDVQPLLEEIKYGDRFVAGAGAGPWPYKNSNCEMMMNVMINS--SKLKNQTRIATVNTEDETCVLETLKGN--ETRFALLANLFLCEGITGKVLKVHAKKRIGKKDFIATMQQALAQHYTDKLVGLGGSFVMKEGKAKQHIMS-DFSEKPLNSVKELDDWLHYYDMSAPLIAVGTFVSAETDLDLRVQHFHSFSHHGEGGHYHIDTTPDTVEYLGYFNLGEVLYRVDKPPMALQFGKD +> +-EKFQLHVPSLEELCEVLESGLKQNFADAKVSVTDCPDLTQEPFKFPVKGLCGKPRITDVGGVPYLIPVVQVEKIYNMNVVSKELELPGAFIIGAGAVSSKTAGMNAELMPLVLTESEGKPAVNASYFSSVNPEDGKCLLEKYSDKFHDCDFGLLANLYACEGKSGKVIEVRASQRTGQDSLVTCMRKAMEQRYPDKSLALGGTFIIQKGKAKIHIMPREFSACPLQSEDDVNNWLKHYEVSAPFICQSVMVSRDPGLDLRVEHTHGFSHHGEGGHYYIDTTPDTVEYQGYFLPAEFIYRIDRPKDTHKIGRD +> +-EKYELDVPPLQELCDVLHNGLKNNFADAQVRVVECPDLSQAPFHFPANGLCGSPRIMDVGGVPYLIPLVQLDKVYNMNTVAKEVELPGAFILGAGAASSRTLGMNAELMPLVVTEIEGRSALNGSYFSYINPADGTCLQEKYSDRFDDCDFGLLANLYACEGKAGQVLEVKASRRTGEDSFVTCLRKTLEKFYSDKCLGLGGTFIMQNGEAKIHIMPQEFSTCPLSSDEEVNKWLKHYTVRAPLICQSVLVSRDPGLDLRLEHTHCFSHHGEGGHYYIDTTPDVVVYLGYFLPAEFIYRIDRPSNTHRIGRD +> +--KRDLHVPSLDEIKDVLKEGLIKNFADVEVEVVDCPDLTKEPFTLAAPGLAGNPTLLEIGGPAFLLPTVQKNKLYDIQQLLDHLQYKEDFVVGAGAGPWPYLNSNCELIMNLSVSP--SSVQNETRISSVNTTNGNCVLQTLPNT--ETRLALLANLFVTGGKPGKVLKVHATRRTGNDDFIASMQKAIALHYPNNLVGLGGTFLMKDGKVKQHVMA-DFSKTPLKTEAQLNNWLHFYNMSTPLIAVGTFVSSESDLDLRVQHFHSFSHHGEGGHYHIDTTPETIEYLGYFNLGTTLYRVDKPLTGIQFGKD +> +-EKAQLHVPDLEELRTVLQTGLEDNFAEVKVSVVECPDLTKEPFNFPVKGLCGSPRVTDVGGVPYLVPLVQKHKEYDMNALSRELELPGAFMLGAGAVSSRIVGMNAELIPLVLTEADGRPAVNSSYFSSINPVDGQCLQERYRDKFSDCNFGLLGNLYACEGRPGKVIEVRAKRRTGDHSIVTALRKTLEVHYPDKSLALGGTFIIQKGNAKIHIMPREFSVCPLTSNEEVNSWLKHFEVKAPLICQSVLVSKDPGLDLRVEHTHCFSPHGEGGHYYIDTTPDSVEYLGYFVPAEFMYRIDRPKETHAVGRD +> +-------------VYEVLQEGLAKNFSTVEVTVVDCPDLREKPWTLAAPGICSRTRIADVGGPPYLIPLPDLSKFYSFSDIAESAELPGGFIIGAGAGSSKFVGVNCEMMANLVIRS-EQKAAIATKIAKVNEENGSCVVENY--N--CGEFGLLGNFLISDGMPGKVLKVSVSKRTGDKNLITCMRHTLANFYGDKPVGLGGVFVIEKGKAKIHIMP-RFSETPLKTDEDVNNWLRFYEMSAPLVCVGVLESHDPGLDLRIEHFHCFSDHGEGGHYHYDVTPDEVHYTGFFAVAEKIYRIDRPLATHHVGRD +> +-EKTPLHAPALEELRGVLQAGLESNFAEVQVSVVECPDLTKEPFQFPVEGLCGNPRITDVGGVPYLIPLVQNHKEYDMNMISKELELPGAFILGAAAAPSRIIGMNAELMPLVLTEAEGRPAVNASYFSSINPADGQCLQEKYGEKYSDCSFGLLGNLYACEGKPGKVIEVRAKKRTGSDSLVTALRRTLEAHYPDKSLALGGTFIIQKGKAKIHIMPREFSVCPLNTNDDVNNWLKHFEVSAPLICQSVLVSRDPGLDLRVEHTHLFSHHGEGGHYYIDTTPDSVEYLGYFMPAEFVYRIDRPKQTHTVGRD +> +-EKADLVCPPLEEVAKVLEKGLSASFKSATVEVVDCPDLTQEPFHLTSKGLGGSPSLLEIGGPPYLLPLVKRDKVYDLKEVPELLGSKSVAVIGAGAGPWPYAGTNCEGVFNLSINN--GKVTNGSRIGKVDPATGTKHHAILPDN--ETRCALLANLFCSEGKTDKVLKVHCKGRTDDMDFITTVKLAIHAKYKDQPIGFGGAFLLKEGKVKQHVMP-DFSKTPINSDEDLNKWLKFFEMSAPLVAVGTFATCDPGLDLRLQHFHSFGLHGEAGHYHYDTTPETVEYLGYFSLAKVVYRLDRPAETHQFGRD +> +-EKLALHCASLREVAEALQKGLLETFNHVDVKVVDCPDMREKPFMLSAEGICERPCLADVGGVEYLAPLAQKDKVYDFKLIAESIDMPTALMIGAGAGPRPHIGTNCEMMANVKLGDE---DLINTRIAKITEDG--SELIHL-KD--STKFCLLGNLYVSEGKPGKVIKVIAKERKGSENFVTAMRKILADYFKDKPVGIGGVFIIKKGKAKLHIMP-DYSDKPLRSDDDINNWLKFFNMSAPLTCLSTFVSHDPGLNLRVEHTHCFSDHNEGGHYHYDITPDSVEYEGYFNVCHELFRIDRPSTRQEFGRD +> +-EKVQLHAPVLEELRGVLQAGLGANFAEVQVSVVDCPDLTKEPFLFPVKGLCGKPRITDVGGVPYLIPLPQTHKEYNMNVISKELELPGAFILGAGAAPSRITGMNAELMPLVLTEAEGRPAVNGSYFSSINPADGQCLQEKYSDKFSDCNFGLLGNLYACEGKPGKVIEVRAKRRTGSNSLVTALRKTLAAQYPEKSLALGGTFIIQKGKAKIHIMPREFSACPLNTDDEVNNWLKHFEVSAPLICQSVLVSRDPGLDLRVEHTHGFSHHGEGGHYYIDTTPDTVEYLGYFLPAEFVYRIDRPKDTHTVGRD +> +-KMHSYHVPDLHEVADVLQKGLANDFAEISAAVVSCPDLTKEPFHLAAEGLGGSPRICDVGGVPYLVPLYNPAKKYNFQEIANLAGVPDGFFVGAAAGPFHVVGSNSELMPNIRCGT---SRRNETHYAKITESG-GHLMEKVPQD--SSDFGLMSNLFLSEGQPGSVLHLSLKRRIGKDNLTAAIRKVLLEAFGEKPVGLGGVFLIKKGKAKLHIMP-DFSTVPLKSDDDVDQWLRYFEFPAPLICLSVMSSCDPGWDLRIDHTHCFSTHGVGGHYHYDTTPEEVEYECFFNVAEKLVRIDQPKETHNIGRD +> +-EKFQLHVPNLAELCQVLQSGLNKNFSDVKVSVTDCPDLTQEPFGFPVKGLCGKPRITDVGGVPYLIPLAQPDKVYNMNTVSKEVELPGGFFLGAGAVSCKTVGMNGELMPLMLTEAEGRPAVNASYFSSINPVDGKCLQEKYSDRFHDCDFGLLANLYACEGKPGKVIEVRACRRTGEDSLVSCMRKTMEEHYGEKSVALGGTFVVQKGKAKIHIMPPEFSACPLNTNEDVNNWLRHFEISAPLIFQTVMVSRDPGLDLRVEHTHGFSHHGEGGHYYIDTTPNSVEYLGYFLPAEFIYRIDRPTETHNIGRD +> +-EKKALHVPELGELATVLQDGLKSHFASVSVSVVDCPDLTQQPFTLAAPGLCGSPRAVDVGGIPNIHPLPKLEKIYDMEKVAELADVPGAFMIGAGAGPYKHVGVNSELMPNLIASTNARERNSETYDMRLDTESGKPILEKC--A--SAECALMVNLYCSEGKPGKVLEVKASKRTGESDFVAAMRKVIQAKYGDKAVGLGGTFLIDRGKAWLHVMP-DFCPTPITNLKEVEAWLKFFEFDAPIVCLSVFYSYDPGLDLRIEHTHCFSHHGAGGHYHYDTTPEDVVYRGYFHPAEWVYRVDRPTEK------ +> +---LDLLVPSLEELAKVFKDGLKKNFCEVDVDVVDCPNLQNSPWNLAASGICGNAKIADIGGPAYLLPLAQLDKVYDMNIIAEKAGCPGGFCIGAGAGNSHYVGVNSEMIANICTKSKSPEAVIGSRISKVHMEDESCVLQDY--K--CCDFALMANVLISEGKPGQVLRVKASKRTGKDNFITSMRTALAAKYGDKSVGLGGVFVIEKGKAKFHIMP-DFSKTPLKTDGXVNNWLKFYDMSAPLVCVGVFESHDPGLDLRIEHFHGYGNHGEGGHYHYDVTPDDVQYVGYFTPATXLYRMDKPPSQRKFGA- +> +-VEKPLFVPPLEEIRDVLKQALPNNFAEVAVEVVDCPDLTKQPFTLAAPGLGGKQKLIEIGGPPYLLPLVQREKIYDVQSLLKRLNYGDILLIGAGAGPWPYLNCNCELVMNLAIAP--SGLKNETRIGSVNKQANCCVQQTLPEK--ETRLALLANIYVSEGKPGKVLKVHVKKRIGQDDFIASIRKAVRSYYKDKLVGLGGTFLLKEGKAKQHVMS-DFSTEPLNSDEALNDWLYFFDMSAPLIAVGTMVTDEAGMDLRVQHFHSFSHHGEAGHYHIDTTPDVAEYLGYFNVGEALYRVDQPPFVQNFGKD +> +-TTRPLHQPPLDELMNVLAGGLTTNFEEATIEIADCPDLDEWPYLFYRKGLCGNPIILDIGGPAYLLPTAQKDKFYDIKLILRHLNYNHDLVIGAGAGPWPHTGCNCELIMKVNIQVRNNGVANGTHYAFVNKSTGECSVTRVLANEDETTFALMANLYVSEGNPGKVIRVRAKKRTGKLDFISCMQNALENHYKDNLVGLGGMFVMKNGKIKQHVMP-NFFDTPLNTETQLNNWLHFYDMETPLVAVGTFVSAETDLDLRVQHFHSASNNQLGGHYHIDTTPDTIEYEGYFNVATTLYRVDQPPNKLQFGKD +> +-EYKPLYKPPLQELADVLNQNLTYNFAEVHAEVVDCPDLRKEPFTLASEGLGGNPRVVEIGGVPYLAPIAQLNKVYDLKDIERFSGLKSAFIVGAGAGPHPYAGVNCEGIINMNVKD--GKVEQQTRISKVVPSDGSQVQEILPNS--ETRIALLANLFYSEGKPGKVLKVHVKKRIGSDDFVTSIRETLAKRYFDKIIGLGGTFLLKEGKAKQHVMP-AFSKTPLNSGKDIDNWLKFYNMSAPLIAVGTLETGDPGLDLRVQHFHSFSHHGEAGHYHIDTTPETVEYLGFFNIGEYVYRVDAPAVSHSFGRD +> +-EHKPLHVPPLEEVSSVLEAALKKNFAEAAVSVVECPNLTKTPYNLGAAGLCGSPRLADVGGVPYLMPTAQKDKLYDIKDLAGCVDLPNSFIVGAGAGPHKYIGVNSELMANVVVGN---EACNGSRAAKVDDAG-KCELLRLPQE--QTGCALMLNMFASEGKGGKVLKVQAKKRIGDKNLVSCLRQALENHYGDQPVGLGGTFRLLQGKAKIHVMP-DFSPVPLTCDNDVNKWLNFYDMEAPMVFLSTLISRDPGLDLRVEHSHGYG-DDRGGHYHYDTTPDTVEYEAYYNVAEFIYRVDKPVATHGFGR- +> +-ENCQLHVPPLSELADVLRQGLESHFAHVQVEVVDCPDLSSSPFHLAAPGLGGEPCLVDLGGVPYLVPTAQRDRTYDLADLPGLMNVKDGLMIGAGAGPWQHLNTNCEMMTNLSLEEGKSNIVNGTRLATVDPAG-QRMLHVVPPEQEQTRCSLLNNLLISRGQPTPVLRIRCQKRTGPNNFVTCMRNTVAQHYGDKPVGIGGVFMLDNGQARLHIMP-DFSPCPLQTDADVNNWLHFYNATGPLINLSVFISHDPGLDLRVEHTHCFSVHGEGGHYHEDVSPETVVYEGYFTPAERLFRIDRPSETHRVGRD +> +-TSRPLHQPPLNELMSVLTEGLTTNFAETTVELVDCPDFGRWPYNFYREGLCGTPIILEVGGPAYLLPTVQRDKFYDIKTILKHINYNRDLVIGAGAGPWPHTSSNCELVMKLNVVNYGMGVANGTHYAFVNKRNGECILQRLPANEDETTFALLANLYVCEGKPGKVIKVHAKKRTGKLDFISCMQKALGNQYKDKLVGLGGTFVMNNGKVKQHIMP-DFSDTPLNSEAQLNEWLHFYDMKTPLIAVGTFVSAETDLDLRVQHFHSAYESRLGGHYHIDTTPETIEYEGYFNVAATLYRVDQPPNKLQFGKD +> +--KLPLKIPDEAELVSVLSKGLLKNFQDVSVNIVDCPDLREKPFQLAAEGICGNPCVADIGGPPFLLPTVHKEKIYNIKTISEISGQQDGFFIGAGAGPAHLIGVNSEMMCNVNLNK-P--DGCQTYIAKVNPENGCFNLKQI--E--HSSFMLMANLLCCEGKQGKVIEVKASKRIGDDNFPTAIRKTLKSQYGSEPVALGGVFIIENGKAKLHIMP-DFSCKPINNVTELNNWLRFYEANAPLVCLGELISHDPDLDLREEHFHCFSPHGQGGHYHYDVTPEEVSYRAYFSVAKTLYRIDKPEHPLNFGKD +> +-EKRQLHTPDLSHVAQVIESGLKENFKEASVNVVDCPDLTSSPWQLAAPGLGGAPRLLDVGGVPYLMPLIQREKVYDLAQVASLAGLPNGFILGAGAGSYRVAGVNCEMMANIKFSDSGAPHNIGSYSAKVSTEDGSAIIEKFP----YTEAGPLANLLLCEGTPGPVLEIKARKRVGEENFVTCMRKSLAAYFGEGPVGLGGVFMIKKGKAKLHIMP-DFSQTPLTTNEGVNKWLQFYNMSSPLTCLSVFISCDPGLDLRVEHTHCFSSHGDGGHYHYDVTPQEVEYHGYYVIAEEIVRIDRPIKTHQIGRD +> +--VKKLYKPNLEELQYALTNGLKSNFAEVSVDVVDCPDLTKEPFGLKSKGLGGSTAVVDVGGPPYLLPNVFRDKLYDFRDVAKTVNLNPCFIVGAGAGPWPYANTNCEMIANVVVQD--GKVDSGTVISKISKDTGKMEVEFISKD--ESRFALLANFFVSEGKESKVLKVNCKKRKGNLDFVTAMRTSLANHFYDKYIGMGGLFVVKKGKVRQHVMQ-DFSEKPLNTEKDLNEWLRFFEMSAPLIALGAFLSQDVDFDLRVQHFHSFSHHNEAGHYHYDTTPDDIEYEAYLNVADTLHRIDQPLVTHKFGRD +> +VQKMPLHQPPLEEVAEVLQKGLANNFSTAEVKVVDCPDLTAAPFDLAEKGLSGRPRILDVGGPDYLKPFPQKEKKYSFADVSNLGELPGSFLIGAGAGPCHHTGTNCELICNVQLGE---GGSNKSRIVKVNEGDGSYTIMEE--K--SGEFSLLGNFFLSQGKPGKVLELKVKDRTGPENFVSCVRKTLAAHYGDKTVGVGGTFLLQTGKANIHVMP-DFSKTALETDEQSDNWLKFYEMDAPLIHVGEIVSGDPKLHLRCEHFHCFSHHGQGGHYHYDTTPNSASYLGYLNLAEAVYRIDIPQEKK----- +> +-EKIQLHVPSLEELSAVLQTELQANFAEVKVSVVACPDLTREPFLFPAQGLCGNPRITDVGGVPYLVPVAKKEKEYDMNVISKEVELPGGFFLGAGAVASRVVGINAEFMPIVLTEAEGRPAVNGSYFSCINPVDGQCLQEKYSDKFSDCHFGLMANLYACEGKPGKVIEVLAKKRTGDQSLVTALRKALENHYPDKSLALGGTFVIQKGKAKIHIMPREFSACPLNTNDEVNNWLKHFEVCAPLICQSVLVSKDPGLDLRIEHTHIFSHHGEGGHYYIDTTPDIVEYVGYFMPAEYVYRIDRPKETHAVGRD +> +-ESCQLHVPPLDELAHVLRQGLALHFAFVQVDVVDCPDLSQSPFHLTAPGLGGDPSLVDLGGVPYLVPTVHRDRIYDLADLPAAMNVKDGSMIGAGAGPWQHLETNCEMMTNLSGKSSSLVVDNGTRLATVDPSG-RRILHVVPPK--QTRCSLLNNLLVSRGLPTPVLRIRCQKRTGPDNFVTCMRNTVRQRYGHQPVGMGGVFMLENGQARLHIMP-DFSPCPLQTDADVNNWLHFYNATGPLINLSVFISHDPGLDLRVEHTHCFSTHGEGGHYHEDVSPETVVYEGYFTPAERLFRIDRPSQTHGVGRD +> +-TSRTLHQPPMDELMNVLAEGLTANFAEATVEMADCPNFSGWPYNFYREGLCGNPIIFEVGGPAYLLPTVQRDKFYDVKSLLRHINYNYDLVVGAGAGPWPHTGRNCELIMKLNIVNLGMGVANGTHYAFVNKSNGECILQRVVANEDETTFALLGNLYACEGKPGKVIKVRAKKRTGKQDFISCMQKALEKHYGDKLVGLGGMFEMKNGKVKQHIMP-DFSDTPLTSEAQLNNWLRFYDMETPLIAVGTFVSAETDLDLRVQHFHSAFENKLGGHYHIDTTPDTIEYEGYFNVAATIYRVDQPPNKLRFGKD +> +-RIHEYHVPPLENVAKVLQEGLQKSFTEVSVTVEDCPDLKKAPFHLAAEGLSGLPRICDIGGVPYLIPLAQPEKRYNYEEVASLAGVPDGFFVGAGAGPCHIIGTNSELMPNIKCSGSGSLTRNETHYARICEDGKSHLMEKVPNG--TADFCLMGNVFLSQGKPGKALRLRLKRRTGSDNLTTAIRKILLETFGDKPVGLGGVFLISKGKAKLHIMP-AFSKTALTSDEDVDKWLHYFEFRAPLICLSVMSSCDPGWDLRIDHTHCFSTHGAGGHYHCDTTPDEVEYECWFNVAEKLVRVDQPKETHQIGRD +> +-SQRQLFAPSLQEIKNVLSPALAENFSEVSIEVVDCPDLTQQPFTLAAAGLGGSKTILEVGGPSFLLPSVQRDKVYELKSILNRINNGKKFVIGAGAGPWPRLSRNCEMMMNVIVS--PTDLKNETRLSWVGPNE-KCILEESLEN--DLRFALLANLYLSEGKPGKVLKVHAKKRTGNLDFIATMQKALESHYKDKLVGLGGTFLLKQGKAKQHVMR-DFSSVPLTTEKALNDWLKFYDMSAPLIAVGTFVSAETDLDLRVQHFHSFSHHGEGGHYHIDTTPETVEYLGYFSVAELLYRIDQPAVGVTFGKD +> +---RSLHQPPADELLNILAEGVTANFKEASVEIVDCPNFNQYPFNFYREGLCGNPIILDVGGPSYLLPTAQKYKFYDIKTLLQKLNYNNALVIGAGAGPWPHTGSNCELIMKVNIVNHDMGVANGTHYAFVQKSTGKCILHRVVANEDETTFALLANLYICEGKPGKVIKVRAKKRTGNLDFISCMQKALEGHYGDKLVGLGGTFMVKNGKVKQHIMP-DFSDTPLNTETQLNEWLRFYEMETPLIAVGTFVSAETDLDLRVQHFHSANEIGLGGHYHYDTTPDTIEYEGYFNMADTLYRVDQPLNKLQFGKD +> +-EKFKLFVPELKDLCEVLQKGLKNNFADVQVCVVDCPDLTEDPFRFPVKGLCGSPRITDVGGVPYLVPLVKVDKDYNMNSVSKDLELPGAFILGAGAVSSKTVGMNAELMPLVLTEAEGRHAVNSSWISSINPADGQCLLEKYSDQFSDCNFGLLANLYACEGKPGKVIEVRAKIRTGEESLVGALRKNMEKHYPDKSMALGGTFIIQKGKAKIHIMPREFSACPLNTDEEVNQWLKHFEVSAPLICQSVMVSRDPGLDLRVEHTHCFSYHGEGGHYYTDTTPDIVEYLGYFLPAEFVYRIDRPEKTHNI--- +> +-ERQALFQPQFEDVVKALSKGLRENFETVNVSLEDCPDLTQEPFHLAAKGLGGSPKIVDLGGPPYLLPNVDKSRYYDCALLGEICQIEPAFIVGAGAGPFQYVGTNSEMIANLIVEK-GKENKVGTRIVKLQNHQDKIEVQVLPKE--ETKCALLANFFLSQGKSGKVIKVHVKKRTGSKDFVTSMREALKSQFGDKAVGLGGAFLVKEGKVRQHVMS-DFSKTPIHTEEELNSWLNFYEMSAPLVALGILISVDPGMDLRVQHFHSFSLHGEGGHYHYDTTPDSVEYLAYLNMAGELIRIDRPEVTHQFGRD +> +---TNLDTPSLAEVRDVLARDLKKTFDYVDVQVVDCPDLTEEPFFLAGKGLGGETSLIDLGGPPYLLPLVKRDKVYDFKQLVKQLKVTPSLLMGACAGPWPYFGKNCEGVCNVLVDG-DNYFKSCSYVGKVTDGDEKLECLPIPDS--ETRFALMANLYCSQGKPGKVLKVNCKKRTGKKDFITAIRTGLAAGFPNKYVGLGGAFLLKEGRAKQHVMR-DFSKTPINTEEELNNWLTFHDMSAPLVAVGTLISNEVDFDLRVQHFHSFSKHNEAGHYHYDTTPETVEYLGYFNVAERLHRVDKPKQTHQLGRD +> +-ETFDLSIVPLEDLAAGLNEHLKYNFEKVKVEVKDCPDLTQPPFTLACKGLTGNERIVEIGGVPYLLPKPRKDKLYDLKDLSKILNLDPCYITGAGAGPWPYAGTNCEMIINMEHNG--DKVNNKTRIAKVNVTDGKCIQEVLPND--ECRNAVLSNLYCSSGEQGKVLEISCSKRIGNDDFITSIRKILGENFKDKILGLGGVFVIKKGKVKQHVMP-DFSNREISSEDDLNKWLKFYEMNTPLIAVGTLVNNDPGLDLRVQHFHSFSHHGEGGHYHIDTTPNDVEYLAYFGLGEKLYRIDRPSQTHNYGRD +> +-EVADLHVPPLDEVAAAIENGLKGNFLHAEVQVVDCPDLTKEPFHLAASGLSGDPSLVDLGGVPYLIPSVRRDKIYDLAEIPSLIDFRESMMIGAGAGPWFHVGTNCELMLNLSISGDETGVRNFSRLATVHQKE--HRQQQLPAD--QTKCALLVNFLVSKGEMSKVLRVECSKRTGSENFITCIRQTLNQHYPDKAIGLGGTFIIDNGKAKLHIMP-DFSSCPLETNEQMDNWLHFYEATGPLVALSTLVSRDPSLDLRMEHSHCFSLHGDAGHYHYDVSPDTIKYYGYFVVAEKIYRIDRPTVTHLIGRD +> +-EEKTLHTPSLDELKTVLSKGLVNNFTEVDINIVDCPNLTQAPFHLASEGLCGRETLIEIGGPPFLLPTVDITKLYDLVSICQKSLNAEHFALGAGAGPWPLVNTNCEGIFNLKNHA-NGHIVSESHLAKITKDRKKCILEKIPNT--DTRCALLANIFACDGKAGKVLKVHCKKRIGNDDFIASIRNTLQKHYGDQTVGLGGVFLLKNGSAKQHVMS-PFSEEPINTEEELNSWLNFFNMPAELIALGTLITNEYDLDLRLQHFHSFSKHGVGGHYHNDVTPDIVEYEGYFMVGRKIVRVDKPKVTHKFGRD +> +-EEKPLYVPSLDEVCKVVASGLKSNFETVQVEVVDCPNLTEDPFHLASQGLNGSPTLLEIGGPPYLLPHVDYTKLYDLVAISERANVTKKLAIGAGAGPYPYVDSNCEGMFNLKVHA-NGHVLSESHLARVTPDRKKVLLEKIPNT--ETRCALLGNIFLSEGKPGKVLKVKCKKRTGNKDFIASIRTTLEQHYGERTVGMGGVFLLKNGKAKQHVMS-PFSETAIYTEDELNSWLNFFDMSATLIAVGTLVTNECDLDLRLQHFHSFSRHGEGGHYHIDTTPDTVEYEGYFNLGEKIVRVDKPVNTHKFGRD +> +-EILKLHCPSLNDISKVLKKRLIGNFATVEVNVTDCPNLTAPPFHLAAAGLCGSTRIVDVGGPPYLLPLPQLDKVYNIADIAKRVNLPSAFIIGAGAGPYNLVGVNSELIPNLKLDPPTGCSAMQSYISKVDLGDGSCIQETI--N--STDFSILGNFFFSEGAQGKVLEVKAKERIGEENLISCIRKALSEEYGDQPVGIGGAFLIERGKAKIHIMS-DFSKEPLENDEAVDEWLKFYEMSAPLVCLGECVSADPGMDLRVEHTHCFSQHGEGGHYHYDTTPEEVAYHGFFNVAECLYRVDRPGETHDLGR- +> +---RTLFTPTLNDIKNVISPALSKNFLETSVEVVDCPDLRESPFKLASAGLGGHPKLCEIGGPPFLLPCVQRDKIYDVRTISKQIHYGDKFIIGAGAGPWPQLSQNCEMMMNLAVDS--AHVINETKLAWVGEEN-QCVLQKCVDS--DTRLALLANLFISEGKPGKVVKVNAKTRIGDLDFIASIQKALSVYYKDQLVGLGGTFLLKKGKAKHHVMP-DFSSVPLTTEESLNNWLRFYDMSAPLVAVGTLVSSESDLDLRVQHFHSFSDHGEGGHYHIDVTPSIVEYLGYFNVADCLYRIDQPTSGLTFGKD +> +-QKMALHQPSLSEVAEVLQKGLAQNFSFSEVSVVDCPDLTKPPFDLAAEGLGGQPRIVDIGGPDYLKPWPQKNRLYNFESIADLAELPGSFLIGAGAGPHLNVGVNCELVCNAKLGL---NARNRTRIVKVDEKVGTFKLEEE--T--SGEFSLMGNFLISEGKPGKVLEIKAKNRTGTENFVSSIHKTLTAHYGDKAVGVGGTFLFQTGKANIHVMP-DFPTTPFENNEQIDSWLRYYEMDAPLINVGEIVSADPENNLRREHFHCFSNHGQGGHYHYDTTPDNASYLAYFNLGEVLYRIDLPE-------- +> +-TTRTLHQPPLDELINVLAGGLTTNFAEATIELVDCPNFNGWPYNFYREGLCGNPIILDVGGPAYLLPTAQKDKFYDIKLLLRHLNYNHDLVIGAGAGPWPHTRCNCELIMKLNIQVINNGVANGTHYAFVNKSNGECILERIVANEDETTFSLMANLYVCEGNPGKVIRVRAKKRTGKLDFISCMQKALENHYEDKLVGLGGMFVMKNGKVKQHIMQ-DFSDTPLNTEAQLNNWLRFYDMETPLIAVGTFVSAETELDLRVQHFHSAYEKRLGGHYHIDTTPDTIEYEGYFNVAATLYRVDQPPNKLQFGKD +> +-KSRTLHQPPLDELMNVLTEGLNANFAEATVELADCPSFDTWPYNFYREGLCGNPIILDVGGPPYLLPTVQRDKFYDVKSLLRQLNYNNSLVIGAGAGPWPHTGSNCELIMKLNVVNLGMGVANGTHYAFVNKSTGGCILERIVPNEDETTFALLANLYICEGKPGKVIKVRAKKRTGELDFISCMQKELEKRYGKKLVGLGGMFEVKNGKVKQHIMP-DFSDTPLTSEAQLNNWLRFYDMETPLIAVGTFVSAETDLDLRVQHFHSAYENNVGGHYHIDTTPDTIEYEGYFNVAATLYRVDQPPNSMQFGKD +> +-KSRTLHQPPLDELMNVLGEGLTANFAEAAIEMADCPELDKGPYNFYRKGLCGSPIILEVGGPSHLLPVVQRDKFYDVKSLLRQLNYNHDLVIGAAAGPWPHTGRNCELIMKLNVTNLNMGVANGTHYAFVNKSTGECILERVAADKDETTFALLANLYVCEGKPGKVIKVRAKKRTGNLDFIACMQKALEKRYGDKLVGLGGMFEVKNGKVKQHIMP-DFSDTPLTTEAQLNNWLHFYEMETPLIAVGTFVSAETDLDLRVQHFHSAYENKLGGHYHNDTTPDTIEYEGYFNVAATLYRVDQPLNKLQFGKD +> +-TTLKLDCPELEEVANALQKGLTQYFAEVEVAAVECPDLREKPFNLAAKGLGGKSAVIDIGGPAFLLPLPDESKIYDIKDIAKIVDLKSCFVVGAGAGPWPYIGKNCEIMANVLIDSCANSTVQKTHIAKVNNKTENCEVEVLPSE--ETRCTLMANLYACEGTPSKVLKIVCKKRKEEENYITAIRLVLEKAFPNQTLGLGGAFLLNKGKAKQHVMP-EFSKVPIKSHKDLDNWLKFYEMSAPLIAVGTFISKDVALDLRIQHFHSFSNHEEGGHYHYDTTPETVEYVGYFNLGQKLYRIDQPERKQYFGKD +> +-EEKPLYTPPLEEIRDVVAAGLTSNFETVTVEVVDCPNLTEDPFHLAGQGLNGNPTLLELGGPPYLLPHVDYTKLYDLVSISQKANCTKKLAIGAGAGPYPYVDSNCEGMFNLKVAA-NGHVLSESHLAQITPDRKRVLLKKIPNT--ETRCALLGNIFVSEGRPGKVLKVSCKKRTGPKDFIAAIRTTLEQHYGERTVGMGGVFLLKNGKAKQHVMS-PFSETAINTEDELNTWLNFFDMSATLIAVGTLVTNECDLDLRLQHFHSFSRHGEGGHYHNDTTPDVVEYEGYFNLGERIVRVDKPVNTHKFGRD +> +-EEKPLYVPSLSELTEVLTNGLKENFADVTVTVVECPDLTVAPFHLAANGLSGSPAIVEIGGPPYLLPLVDRSKLYDLAEITRKV-LPNAIVLGAGAGPYSLINSNCEGIFNLKIHS-DGTVVNNTHIAQVSPGNETCALIKVPNA--ETKCALLANLYLSEGKPGTVLKVQCKHRTAPENFVSSCRNAVTKAFADKVVGIGGVFLLKNGKAHQHIMR-DFSKTPIYTEDELNGWLKFYEMPGTLIAVGTFITDEADLDLRLQHFHSFSTGNWGGHYHYDTTPDTVEYEAYFNVGERVVRIDKPTNTHKFGRD +> +-EKVKLHAPALEELRGVLQAGLGANFAEVQVSVVECPDLTKDPFQFPVQGACGSPRITDVGGVPYLVPLVQKHKEYDMNVLSKELELPGAFLLGAAGAPSRILGMNAELMPLVLTEAEGRPAVNRSYFSSINPADGQCLQEKYCDKFSDCSFGLLGNLYACEGKPGKVLEVRARKRTGVHSLVTALRNVLHSHYPDKSLALGGTFLIQKGKAKIHIMPREFSACPLNTNDDVNNWLKHFEVSAPLVCQSVLVSRDPGLDLRVEHTHCFSHHGEGGHYYIDTTPDTVEYLGYFMPAEFVYRVDRPKETHGVGRD +> +-TSVKLDCPELEDVAIALQKGLPQYFAETEVAVVDCPDLRKGPFNLAAKGLGGNTAVIDIGGPAFLLPLYDETKIYHMKDIASTVGMKSCFIIGAGAGPWPYIGKNCELMANILIDDSTSSIVQKTHIAKVNDKTEDVEVEVLPNS--EMRCSLLVNLFACEGTSSKVLKVFCKKRKEDENFITAIRTTLEKAYPDKTLGLGGAFLLKEGKARQHCMP-EFSKVPIRSNNDLNNWLKFYEMSAPLVAVGTLLSKDIDLDLRVQHFHSFSNHGEGGHYHYDTTPETVEYLGYFNLGQTLYRIDQPEKKQYFGKD +> +---RDLHVPSLEDAQKALSKGLKNVFAEVSVDIVDCPDLSAEPFNLACKGLGGTTSVVEVGGPPYLLPKVDRQKVYDVKDIVKAIGLQQCFVIGAGAGPWPFIGKNAEMVANVYIDG--NNVKSLTHIAKLKDDGNNIEVSVLPNT--ETRFALLANLFFSEGVQSKVLKVHCKKRTGSDNFVTAMRNALHDDFPDKVVGVGGAFLLKSGKALQHVMP-DFSKSPLNSDEELNKWLEFYSMSAPLVAVGTLVSSDIELDLRVQHFHSFSSHGEAGHYHQDTTPNEVEYLGYFNLGQKIYRIDKPPLTHSWGRD +> +--SRALHQPPLDELMNVLAGGLTANFEEATVEMADCPNFSGRPYYFFKEGLCGNPIILEVGSPSYLLPTVQRDKYYDIKSLLQQLNYNHDLIIGAGAGAWPLRDSNCELIMKLNLKNDNFQVRNGTHYAFVDKNNQGCKLERLAENDNITTFALLANLYVCEGKPGKVIKVRAKKRTGKLDFIACMQKALEKHYENKLVGLGGMFEMKNGKVKQHIMP-DFSDTPLTTEADLNNWLRFYDMETPLIAVGTFVSAETDLDLRVQHFHSAFDPGLGGHYHIDTTPDTIEYEGYFNVATTLYRVDQPPNKVQFGKD +> +-HTKSLYQPPLTEVAEVFRSYLPTNFQEVNVSVVECPDLTSKPFLLAAGGLNGNAKLLEIGGTQYLLPLVTREKLYDLLDIAKSVALEPAFLIGAGAGPHPFIGANCEGIVNLKIEK--GVADQQTRTSKVEGADEYMVVQILPNN--ETRIALLGNIFASEGKPGKVIKVHVKKRTGAKNFIETLRNAIEEKYGDQLVGIGGAFLIAEGKAKQHVMR-DFSKTPLTSEDDVNNWLKFYEMSAPLTALGTFTSNDGDLDLRVQHFHSFSTHGEAGHYHYDTTPDTVEYLGYFNVAQEVVRVDKPESGSKLGRD +> +-EEKALHTPSLGEIRDVLATGLKSSFATVNVEVVECPDLTKAPFHLAGRGLNGSPTLVEIGGPPYLLPNVDRSKLYDLVSVSQRALHDTKIAIGAGAGPFPLVNSNCEGMFNLRYTP-PGTVVSESHLAVISPTDRTVTVHKIPNT--ETRCALLGNILVAEGKPGQVLKVSCKRRTGKKDFIASIRTCLEGHYGERTVGLGGVFLLQTGKAKQHVMS-PFSETPINTEEELNEWLNFYDMPAPLINVGTLVTTECDLDLRLQHFHSFSTHGHGGHYHIDTTPDIVEYEGYFIVGERIVRVDKPVNTHKFGRD +> +VQKIDLKPPPLEDLIDCIRSGLGQSFKSISVSVDQCPDLRQAPYHLAFTGLCERPRIADVGGQPNLAPTPDLTKKYDLLEIARLMEMPEGALLGAAAGPFHVVGMNSELMPNLSWKN--KEVSNETHFAKVRSDG-SAVCEKL--S--SHDCGLMANLFGSLGRPGPLLHITASSRTGPLNFTEAIRGALQDAFGTRTISLGGVFLISEGKAKLHVMP-DFSPTPLVTDKQKEEWLKFYEMKAPLVCLSVLHSHDPGLDLRIEHTHCFSDHGEGGHYHYDTTPADVKYEAWFNIAEVLYRIDRP--------- +> +-TSRTLHQPPLDELMNVLAGGLTANFAEATVEMVDCPNFNGWPYNFYQEGLCGNPILLEVGGPAYLLPTVQTDKFYDVKSLLRQINYNDTLVIGAGAGPWPHTGCNCELIMKLNIVNLGMGVANGTHYAFVNKSNGECKLERIVANEDETTFALLANLYVCEGKPGKVIKVHAKKRMGNLDFISCMQKALAKHYEDKLVGLGGMFEVRNGKVKQHIMP-AFSDTPLTSETQLNNWLRFYDMKTPLIAVGTFVSAETDLDLRVQHFHSAFENRLGGHYHIDTTPDTIEYEGYFNMAATLYRVDQPPNKLQFGKD +> +-KIHDYYVPLLENVATALQRGLTESFAEVLVRVEDCPDLTKAPFYLAAEGLSGSARICDVGGVPYLIPVARPEKRYNYEEIALLAGVPDGFFVGAGAGPCHVIGTNSELMPNIKCGNSGNLTKNKTYYARIREDG-SHLVEKVPHG--SADFSLMGNVFLSEGKPGKVLHLHLKKRTGPDNLTTSIRKILLKEFGDRPVGLGGVFLITKGKAKLHIMP-GFSKDPLTNNEDVEKWLHFFEFSAPLICLSVMSSYDSGWDLRIDHTHCFSTHGAGGHYHNDTTPEETEYDCWFNVAEKMVRIDQPKETHQIGRD +> +-EEKPLHVPPLQELQSVIQGALDSNFGHVDVSVVPCPDLKGSQFGLVESGLGGKPTLLEAGGPPYLRPLVQRDKLYNLKEITRKIQGPGKFAVGAGAGPWPIRGSNCEGIFNLSVSE-EDKLTNGSYTATVRGEKEECVLEKISDS--EPRCALILNLFLSQGQPGEVLKITAKQRTGEQNFIECIRKGLEQHYQDKPVGLGGIFLIKKGKVHQHVMR-DFSKTPIYTTEQIQQWLKFYEMPAQLNALGTLVTKDLGLDLRLQHFHSFSFTNWGGHYHYDTTPDIVEYEAYLNVAERVVRVDRPRLTDQLGRD +> +-EEKPLYTPSLVEIRDVLASGLKTCFATVNVEVVDCPDLSKAPFHLAGTGLNGSPALIEIGGPPYLLPTVDGTKLYDVVSVAKRALHDDGIAIGAGAGPFPLVDSNCEGMYNLRYTP-PGSVVSESHLAMVNAKG-EVIVRKIPNT--DTRCALLANLLVSEGNPGPVLKVSCKRRTGNKDFIASIRTCLEDRYGERTVGMGGVFLLQSGKAKQHVMS-PFSKTPINTEEELNEWLNFFDMPAPLINVGTLVTNECDLDLRLQHFHSFSTHGHGGHYHIDTTPEVVEYEGYFVVGERIVRVDKPVNTHKFGRD +> +-SQRQLFVPSLQEIKNVVSPALAENFSEVFVEVVDCPDLTQQPFTLAAAGLGGVKKILEVGGPSFLLPIPQRHKIYELKSILDCINDKRAFVVGAGAGPWPRLSKNCEMMMNVVVSA--KDLKNETRLSWVGRNE-ECILEESLGN--DTRFALLANLYVSEGTPEKVLKVHAKKRTGKLDFIATMQKALQAHYKDKLVGLGGTFLFKQGKVRQHVMR-DFSTAPLTTENALNNWLKFYEMSAPLVAVGTFVSAQTDLDLRVQHFHSFSHHGEGGHYHIDTTPDIAEYLGYFGVAESLYRIDQPAVCVDFGKD +> +-EEKPLHQPPLQELKQVIQSTLLKNFENVSVDVTSCPDLTASPYNLMDSGLGGSPILLEAGGPPYLLPLVQREKLYNIKEMCQKAMGGEGLAMGAGAGPYPLRNSNCEGIYNMAVSA-DGKITNGSYTAKVSGKEEACALEPIPNS--EPRCALLLNLFVCRGEPGQVIKITCKKRIGKQNFIECIRQGLLEKYGDKCVGMGGLFLIKRGKVFQHVMR-DFSKTPITSEVELNQWLKFFEMPATLNAVGTLITHENDLDLRLQHFHSFSTSNWGGHYHYDTTPETVEYEAYLNVAERVVRVDKPIETHKFGRD +> +--SKILDVLPLQDVARCLEEGLLANFSTASVEVVDCPDLTQSPWSLASQGLCGSTRLLDIGGVPFLMPVVKRDKLYDMKDYPRLTGSPQGLVIGAGAGPWPYLNRNAEMMPNMFVNS-DNSIRQETRITRTHDEDGSYSTLKLPSS--ETRNAVLGNVFISDGKPGKVLRIKASKRIGDNNFVTCMRESLNSAYPDKAIGLGGVFCIQKGTAKFHVMP-DFSPCPINNNDQVNEWLQFYEMTAPLTVLSVLISRDPGLDLRVEHSHGWGENNQGGHYHYDTSPDTVEYIGYYNIADTCYRIDKPVDTHNFGRD +> +-AKLELYQPEANELRSVLEKGLKNSFEEASVQIIDCPNLKKEPFNLAAKGICGRPTLIDVGGVRNLQPVPLRNKIYNLDKLTQIAHNPEAFLMGAGGGPFHITSVNCEVSILTRWDPHTGHGRNLSYIARLDPVN-EYKLLQMP-E--NRECGLMLNALVCEGKEGKVMQVKAKKRTQDTNFITAMRETLKVAYGDKPIGFGGVFLLQSGNAKLHIMP-DFPIYPLNDDATVNSWLKFYDMHAPLACLSTFVTNDPNMDLRIEHTHCYSDHGQGGHYHHDTTPDTAEYLGYFVLCNTLYRIDKPAMLHR---- +> +-EEKTLYQPPLEELREVIQSTLAKNFENVSVEVTACPDLKSAEYGLMDSGLGGSPMLLEVGGPPYLLPLVQRDKLYNVKEICQKSMNGGKLAVGAGAGPHPLRSSNCEGIYNMSISS-DGQLKNGSYTAKVSGLEESCVLESIPDT--EPRCALLLNLFVCRGEPGSVIKITCKKRTGHLNFIECIRQGLLQKYGEKCVGMGGIFKINQGKAYQHVMR-DFSKTPINNEKELNQWLKFFEMPATLNALGVLITHENDLDLRLQHFHSFSTSNWGGHYHYDTTPETVEYEAYFNVAERIVRVDKPLETHKFGRD +> +--KKELDCPKLEDIQKVLLKALKNNFSEANVDVVDCPDLTAEPFCLASKGIGGSTAVVEVGGPPYLLPNVDKEKVYDIKDIVKAIGIKPCFVLGAGAGPWPFVGKNSEMMANVLIDG--DQVLSKTHVAKLKDDGKDINVSVLPPT--ETRFALMGNLFFSEGIQSKVLKVHCKNRIGVDNFITVLRKGLEDEFKDKYVGLGGAFLIKSGKALQHVMP-EFSSTPIYSEEELNKWLNFYEMSAPLVAVGTLMSSDVDFDLRVQHFHSFSEHGDAGHYHQDTTPNEVEYLGYFNVGQYIYRIDKPLHTHQFGRD +> +VEKLDLHPIPLQELSDAIKTGLAHQFESTSVSVEQCPDLQQTPYNLAFAGLCGSPRIADVGGQPNLAPTPDFSKKYDLLDIARLMELPKEALLGAAAGPFHVVGTNSELMPILQWNG--AEVVNQTHFAKVKDDG-SALCEKL--A--SHDCALMANLFGCEGLPGDVLHITASSRTGSLNFTEAIRRSLEDAYGQKTISLGGVFLISKGKAKLHIMP-DFSFVPLITDEQKQKWLKFYETEAPLVCLSVLHSHDPGLDLRIEHTHCFSDHGEGGHYHYDTTPKDVQYEAWFNVAKILYRIDRP--------- +> +---IETLKPSNEELLAIFEGALKENFKDVEIKLCQCPDLTAEPYNMTSTGFGRKMVIAEVGGPGNLFPVIHKEKDFDLKEICNGCEAPASFVFGPGAGPWQVVGRNCEMVADANFSSS----KVATKIASLPPGHTAYKMEVI--S--SPKFSLMANLAVSAEGPAQVVYCKASVRTGKDNFPETIRKGLAKHYGDKCVSVAGVFMMLKGEAKLHVMP-DFPGCNFSSREELKQWLRFFTMKAPLVCASVFHSYDPGHKLRMEHTHCYSSHGDAGHYHYDTTPDTVVYEGYFTAAEKIYRFDE---------- +> +-TSRTLHQPPLDELMNVLAGGLTANFEEATIDLADCPNFSRRPYNFFREGLCGNPIIFEIGSPAYLLPTVQRDKIYDIKTLLQHINYNHDLVIGAGAGPWPRTGCNCELIMKLNLKLDNFQVQNGTHYAFVDENNGRCRLQRLADNDTESTFALLGNLYACEGKPGKVIKVRAKKRTGKLDFISCMQKALEKHYENKLVGLGGMFEMKNGKVKQHIMP-DFSDTPLTSEIHLNNWLRFYDMPTPLIAVGTFVSAETDLDLRVQHFHSAFELGLGGHYHIDTTPDTIEYEGYFNVAATLYRVDQPPNKLQFGKD +> +--TRALHVPPLEEIRDILREALPANFAEVTIDVVDCPDLTQQPFSLAEPGLGGGTKLLEIGGIPYLFPHVHRDKVYDIKSILQNVDHSGKFIIGAGVGPWPLVKSNCELMMNMSISPTESSTKNATHICMVDKGDGKCVDKTLSAS--ETRFSLSANLFLSEGKPGKVIKVHVKKRSGSNDFIGSIRAALAARYTEQVVCLGGAFLLKEGKAKLHIMS-DFTEAPLISYDDLKKWLNFFEMSAPLVALGTLVTASTDLDLLVEHFHTFSDHGEGGHFHFDTTPDTAEYVGYFNVIETVYRVDQPP-------- +> +--KIILNAPSLEELRPILENALKKNFEQVSVDIVECPNFKAPPFSMSGAGIGNDLRIGEIGGIGNLYPSPRTDKVFDLKEICVTCEIPEAFIFGPGAGPFHVVGHNCEMVADANFIE--RQNNVATKIAEITASGKGYRMSTI--D--KTGFALMANLAISDGRPGKVLRIRATKRNGEMNYPESIRKALTAHYGETLVSLAGVFVLKKGKVHMHVMP-DFPGCPWKTHEQVNEWLKYFEMNAPLVCTSVLHSNDVGGKLRLEHTHCFSEHGDAGHYHYDTTPNDVDYDGYFAPANVIYRIDM---------- +> +-EEKPLYVPSLEELQSVIQGALDKNFATASVNVGTCPDLKAPQFGLVESGLGGKPILLEVGGPPYLLPLVQREKLYNIKEITRRAQGAQGFAIGAGAGPFPIRNSNCEGIYNLSVSA-ENELNNGSYTATVRGEHEECVLERIPST--EPRCALLLNLFVCSGETGPVLKISAKRRKGEFNFVECIRKGLEKHYDDQVVGLGGIFLVKSGAVHQHVMR-DFSTTPIHTDEEVNQWLKFYEMPAQLNAVGTLVTKEHDLDLRLQHFHSFSFSNWGGHYHYDTTPDSVEYEAYLNVAERVVRVDPPADTHKVGRD +> +--KLQLHVPRLVELAEIIQAGLAENFATVHVNVVDCPNLTEEPFFLAAKGLGGSPRIADVGGNGNLYPDVRKDKLYNMRQVCETSNLPHAFAIGPGAGPLHLLGCNSEMVHNVHFVD-DKHSIFKSYVIFLNQSSEPYTVKML-DNKFANEFTLMANLLLTEGKTDKVLKIVAKKRIGEENFVTCMRLALAKKYGDKPVGLGGVFVIKSGKAKLHIMP-ELPEKFSNTDEILNNWLKYFEMSAPLVCTGVFISHDPGLDLRPEHTHCFSDQKHGGHYHYDTTADEIEYEGYFTPAESLYRIDRP--------- +> +-EEKPLHTPSLVELRDVLAVGLKSCFATVNVEVVECPDLSKAPFHLAGCGLNGNPALVEIGGPPYLLPTVDRTKLYDIVPIAKRALHDDQIAIGAGAGPFPLVNSNCEGMFNLHYSP-PGKVVSESHLAMVTPER-EVIVRKIPNT--ETRCALLGNLLVSEGNAGPVLKVSCKRRTGNKDFIASIRTCLEDRYGEKTVGMGGVFLLQAGKAKQHVMS-PFSTSPIHTEEQLNEWLNFYDMPAPLVNLGTLVTNECDLDLRLQHFHSFSTHGHGGHYHIDTTPEVVEYEGYFVAGERIVRVDKPVHTHKFGRD +> +-EEKPLHVPPLSELQNVIQGALSGNFAQVEVSVGACPDLKAARFGLVESGLGGRPTLLEAGGPPFLLPLVQRNKLYNIKEITRKIQGPGKFAVGAGAGPWPIRSSNCEGIFNLSVSE-SGELTNGSYTATVRGEQEECVLEKIPHT--EPRCALLLNLFLSQGAPGQVLKISAKQRTGEQNFIECIRKGLEEHYGDQVVGLGGIFLIKKGAAHQHVMR-DFSKTPIHTDEEVNEWLKFYEMPAQLNAVGTLVTKEHDLDLRLQHFHSFSFSNWGGHYHYDTTPDIVEYEAYLNVAERVVRVDKPLSTHKVGRD +> +-ESVALHMPSLDELAEVISVGLRKNYKESSCSVVDCPDLSKEPFGLAANGICGRTKLVEVGGVPNLVPLSKMEKVYNLQTISERIGAPGCFVLGAGAGSKHVVGCNCEMMPNFRCRGGEKERVNLTHIAKVKQDG-GYLLQNYENDYASSEFTLLANLFCSDGNPGKVLEVHAKSRIGDKDLVGCIRGALKEYFGRRPIGMGGTFLVKDGRIKIHVMP-DFSETPLTSEEDVNNWLRFYEVNAPFTCLSTFITEDCGLDLRLEHTHGYNTNGVGGHYHYDTTPEEVEYLGYFSPAEFIFRVDRPTETHQIGRD +> +-EEKPLHMPTLQELRDVLADGLKSCFTTVDVEVVECPDLTRAPFHLAGGGLCGSATLVEIGGPPYLLPTVDRSKLYDVIEVSKRA-LPKSISIGAGAGPFPLVDSNCEGIFNVRHSP-PGTIVSESHLAIVAPETGKMSIRKIPNT--ETRCALLANLLVSEGRPGPVLKVSCKRRTGNKDFIASIRTCLADRYGEQTVGLGGVFLLVAGKAKQHVMS-PFSTTPIHTEEQLNEWLNFYDMPAPLINLGTLVTNECDLDLRLQHFHSFSTHGHGGHYHIDTTPDTVEYEGYFVVGERIVRVDKPLITHKFGRD +> +-EEKPLYVPPLQELKEIIQSALTKNFENVSVEVGDCPDLTDPFYGLLSSGLGGSPVLLEVGGPPFLLPLVQRSKVYNVKEIVQKA-LPGKLAIGAGAGPFPLRNTNCEGIFNMAIDE-QGNLKNGSYTAKVHGAEEVCVLERIPDS--DPRCALLLNLYISRGAPGPVVKVKCSKRTGEQNFVECVRKGLESHYKDKCVGMGGIFVLKKGAAHQHVMR-DFSKTPLHSEEELNNWLKFYNMPAQLNAVGTLLTNEHGLDLRLQHFHSFSKSNWGGHYHHDTTPDEAEYEAYLNVAERVVRVDRPLESHKIGRD +> +-EEKSLHKPPLEELQNVLQSILTRNFENVTVNVSQCPNLNAPEYGLMDVGLGGCPTLLELGGAPYLLPKVQKDKLYDIKAICRKSMGEGKLAVGAGAGPYPLRTTNCEGIFNLSISA-QDEIKNGSYTAKITGLQEDCLLEPIPDT--ETRCALLLNLYVCRGEPGPVLKITCKKRTGHMNFIECIRKGLYEKYQDKCVGLGGLFLLKNGKAHQHVMR-DFSRSPIHTESELNQWLKFFEMPGTLHAVGTLVTHEHDLDLRLQHFHSFSRTKWGGHYHYDTTPDTIEYEAYFNVAERIVRVDKPKTTHKFGRD +> +-EEKPLHTPSLTELRDVLAAGLGSCFATVSVEVVECPDLSKAPFHLAGSGLNGTPALIEIGGPPYLLPVVDRTKLYDLVSVTKRALHGEEIVIGAGAGPFPLVSSNCEGMFNLRYSP-PGTVVSESHLAMVTAER-EVVVRKIPNT--ETRCALLANLLVAEGNAGPVLKVSCTKRTGNKDFIASIRTCLDDRYGERTVGLGGVFLLREGKAKQHVMS-PFSTKPIHTEEQLNEWLNFYDMPAPLVNVGTLVTNECELDLRLQHFHSFSTHGHGGHYHIDTTPETVEYEGYFVAGERIVRVDKPVNTHKFGRD +> +-EEKPLHVPPLSELQKVIQGALSENFRTVEVSVGSCPDLKASQFGLVESGLGGKATLLEAGGPPYLRPLVQRDKLYNLKEITRKAQGPGQFAVGPGAGPWPIRHSNCEGIFNFSLNE-KDELTQGSYTATVRGETEECVLERIPET--EPRCALILNLFLSEGKPGEVLRIFAKQRTGDENFVECIRKGLEKHYGDEVVGLGGIFVIKKGAAHQHVMR-DFSKTPIHTQEQIQNWLKFYEMPAQLNAVGTLVTKDMGLDLRLQHFHSFSFENWGGHYHYDTTPDKVEYEAYLNVAERVVRVDRPRVTDQLGRD +> +-ENVALHVPSMEELAEVVGVGLKKNYKEWSCSVVDCPDLSKAPFGLASNGICGRTRLVDVGGVPNLVPVSQMEKVYNLQDISERVGTPGCFILGAGAGSKHVVGCNCELMPNFRCEGGERERVNLCHVARVKSDG-GYLLQNYENDGSSSEFSLLANLFCSDGKQGKVLEVRGKCRIGEKDLVGCMRGALKEHFGNRPIGMGGTFLVNKGKIKIHVMP-DFSETPLTSDNDVNNWLKFYEVTSPFMCLSTFITEDCGLDLRVEHTHGYNNSGVGGHYHYDVTPDEVEYIGYFTPAEFIYRVDRPSTTHNIGRD +> +-EEKPLHVPTLEELQHVIQGALAGNFKTVSVSVGACPDLKAAQYGLVESGLGGKATLLEVGGPPYLLPLVQRDKLYNITEMTRKIQGAGKFAIGAGAGPYPIRSSNCEGIYNLSVSA-QNVLTNGSYTATVRGEQEECVLERIPSS--EPRCALLLNLYLCQGQPGPVLRINAKQRKGELNFIECIRKGLEQHYGDKVVGLGGIFVIKRGAAHQHVMR-DFSQTPIHTDEEVNEWLKFYEMPAQLNALGTLVTKEHDLDLRLQHFHSFSFSNWGGHYHYDTTPDIVEYEAYLNVAERVVRVDKPLDTHKVGRD +> +IEEKELFQPPLKEVCDVFLSGLLKNFKNASVTIEECPDLTKEPWTLASNGICGTPYLLDVGGVPYLTPNPQFHKIYNYETIAKVLPFDNVLILGSGAGPFHKIGYNCELMANMYISK---VFKNESRIASIDKNG-SYELQI--NQ--EKEFGILGNFLASEGVPGKVIKVNASVRKGGKNFIECIRESLRAKYPDNMIGMGGVFVIKSGKAKIHVMP-DFSCSPLNTKEDVDNWLRFFEMSSPLVCLSVFYNIDQGMDLRIDHTHCFSHHGDGGHYHFDTTPDDVSYEGFFVLAEKVLRIDRP--------- +> +VEEKPFYQPPLQEVVDVLSAGLPSNFESVKVEVVDSPDFTKAPFDLTSPGISGNVKLIELGGPPFMLPTVQRDKVYELAGLARALGRENALVAGAGAGPWPWAGVNCEGIINLSIRD--GKVNQGTRVVTVDPPSSGYKLQRLPQN--ETRTALLGNFLISDGLPGKVIKVVAEKRIGESNFISAIRETLLKHYGDKVVGLAGTFLLLSGRAKHHVMP-DFPAEPIHTEAGVDRWLHYYDMPAPIFYVGTMVTGDLGLDLRLQHFHGYG-AGVGGHYHYDTTPGAARYEGYFTLAESVLRVDRPPVTHGLGRD +> +-EEKQLYRPSLAELKEVIQSALVKNFENVTVEVTDCPDLKTAEYGLMDSGLGGSPTLLELGGPPYLLPLVQREKLYNVKEICQKT-MGGGLAVGAGAGPYPLRNSNCEGIYNMSISA-EGQLKNGSYTAKVSGLEESCVLESIPDT--EPRCALLLNLFVCRGEPGQVLKISCKKRTGHLNFIECIRQGLLEKYQDKCVGMGGMFKINQGKAHQHVMR-DFSRTPIVDEHELNQWLKFYEMPATLTALGTLITHENDLDLRLQHFHSFSNSNWGGHYHYDTTPEIVEYEAYLNVAERVVRVDKPKETHKFGRD +> +-EEKPLHVPTLEELQQVIQGALRKNFATASVQVGDCPDLKAPQYGLVESGLGGRATLLEVGGPPHLLPLVQRDKLYNIKEIARRIQGAGKFAVGAGAGPYPIRSSNCEGIYNLSVSA-SDELTNGSYTATVRGEQEECVLERIPST--EARCALLLNLYLSRGEAGPVLKISAKQRKGELNFIECIRKGLEEHYGDRVVGLGGIFVIKKGAAHQHVMR-DFSKTPIHTDAEVNEWLKFYDMPAQLNALGTLVTKEHDLDLRLQHFHSFSFSNWGGHYHYDTTPDTVEYEAYLNVAERVVRVDKPLATHKVGRD +> +-KSRPLYQPSLEELVDVLEEGLRANFVEVTIGITDCPNFNEQPYNFHREGLCGNPIVFDIGDPAYLLPSAQRDKFYDVKSLLRHLNYNTTLVIGAGAGPWPRTGCNCELIMKMHLSP-RQEVENATRYAFVGKTNEECVLHQVPVNEDETTFALLGNLYVCEGRPGQVIGVRAKKRTGNLDFIACMQKALGSRYKDKLVGMGGTFVMRNGMIKQHVMR-DFSKTPLNSEAELNNWLRFYEMETPLTAVGTFVSAETDLDLRVQHFHSASDNKLGGHYHIDTTPDTIEYEGYFNVATIIHRVDQPANKLQFGKD +> +VEKKALHVPSLDELSAVLQHALQANFANASATPVECPDLTAAPYHLAAPGINGSPRLADVGGVPYLIPTANRNVLFDLQEVATKVDLPGAFFIGAGAGSWKYIGTNCELMPNVHLGAS----NNLTTTAIVAHD--KCELRPY--D--TTQVGVLCNVLASEGVRGPVVHVKASVRTGPKDFLSCLHQAIVSRYGQQGVGLGGVFVIREGKAKIHVMP-DFSPVPLCSDAEVDQWLKFYEMQSPLVCLSTMVSGDLGLDLRLTHTHCFSNHGEGGHYHYDTTPEVVEYEGYLVPAEHIYRIGRPQVTHKVGRD +> +VEKFAFHVPSLEELAGVLQKGLKENFADAQVSVVDCPDLTQEPFNFPAKGNLAFSTSADVSKGVRGVRVVL--QVYDLNTVAKDIELPGAFILGAGAVSSRVLGVNAELIPIVQTKNEKKPAVNGSYIAQINPADKGCLLEKYSSKYSDCEFGLLANLYASEGQPGKVIEVKVNGRTGELNFVSCLRQTLEKHYGEKPVGLGGTFIIQKGKAKIHIMPPEFSACPLNTDEDVNNWLKFFEMKAPLICQPVIVSRDPGFDLRLEHTHCFSQHGEGGHYHADTTPEAAQYRGYLLPAELLFRIDRPKATHRVGRD +> +-EEKPLHVPCLSEIQRVIQGALSENFKTVDVSVGPCPDLEEPQFGLVESGLGGNPTLLEAGGPPYLRPLVQREKLYNLKEITRKAQGSGEFAIGPGAGPWPIRNSNCEGIFNFSLSE-KDELKQGSYTATVRGDQEECVLERIPET--EARCALILNLFLSEGKPGEVLRISAKQRTGKENFVECIRKGLEQHFGDKVVGLGGIFVVKKGCVHQHVMR-DFSKTPIHTQEQIQEWLKFYEMPAQLNAVGTLVTKDLGLDLRLQHFHSFSFENWGGHYHYDTTPDVVEYEAYLNVAERVIRVDRPVVTDQLGRD +> +-VKKPFHVPELRAVADVLNNGLKAHFSEVLVEVVDCPDLTQAPFHLANKGLNGNPNLLDIGGPSFLIPLVDRTKVYDLKDMAEISGNKPAFLIGAGAGPFNHLKTNCEGIFNINVGD---EIKQESRIGMLNRETGSPMELKLNNS--ITEFGLLGNLYSSQGKEGKVLKVHAVKRIGTIDFIASIRSVLSEAYKDGIVGLGGTFIIKKGSAKLHIMP-DFSDTPIEDDETLNKWLQFFNMSSPLVAVGTLVTGTYNMDLREQHFHMFSDHGNAGHYHIDTTPDVVEYLGYFNVANHIFRVDQPKTDAAFGKD +> +-EEKPLHVPPLSELQKVIQGALCANFATAEVSVGSCPDLKAGQFGLVESGLGGKPTLLEAGGPPYLRPLVQRDKLYNLKEITRRSQGPGKFAVGPGAGPWPIRNSNCEGIFNFVVSE-KDELTNGSYTATVRGEQEECVLERIPDT--EPRCALILNLFLSEGKPGEVLKIRAKQRTGQENFVEYIRKALEQHYGDQVVGLGGIFLVKKGCVHQHVMR-DFSTTPIHTHEQIQQWLKFYEMPAQLNAVGTLVTKDMGLDLRLQHFHSFSASNWGGHYHYDTTPETVEYEAYLNVAERVVRVDRPVVTDQLGRD +> +-ETKDLFVPDNKELKEALTLGLKKNFQEVSVDFVDCPDLSGEPFNLASSGLCGNPTILEYGGAPYLLPLVQRNKLYDLNEICQERNMKEYLAIGAGAGPYVFCNTNCEGIFNLAGRQPDGKIVSKSHLALVDKDK-QCERRNIPAS--ETRTALLGNIYLSEGKGGQVLKINCKKRTGTNNFITQIRESLSDHFEGKDIGLGGTFLLKSGKAHQHVMQ-DFSQTPIYTEDEINTWLKFYDMPAPLVAVGTLVTNEMDLDLRLQHFHSFSPSHWGGHYHYDTTPDTVEYEGYFGIGEKLFRIDKPEETHKFGRD +> +IEEKPLHVPPLEEIQKVIQGALCANFKTVEVEVCPCPDLKAKPFCLVESGLCGCPTLLEVGSPKFLIPMVQRDKLYNIPEIIRKVQGPGRFAVGAGAGPWPFFNSNCEGIFNMSVDK-DDKLTNGSYTATVRGENEECVLEKLPDT--EPRCALLLNLFLSQGLPGKVIGIHAKKRICEKNFVECIRIGLDEHHGDKVVGLGGIFVMKRGCANQHVMR-DFSKTPLNSEEDVEKWLKFYEMPAQLNCLGTMVTKDLDLDLRLEHFHSFSFSNWGGHYHYDTTPDSVEYEAYLNVAERVLRVDRPV-------- +> +---IDNHVPSLEELKMVFQTSLLSNFENVEVNIVDCPDLSKPPFNQKSSGFGHNLRIAEVGGPGNLYPGFHIDHQFDIPKIGKVCEHPEAAVFGPGAGPWPIVGQNCEMVADVNLKT----GEVGTRIAEINSNSDKRYVQRI-ID--EPKFSLMANLALSDAKSSTVVHFKASVRKGEKNLTNCIRDGLQEHFGKKIVSLAGQFIIQTGKARLHVMP-DFPGCPFENNAEVDKWLNYFEMSAPLICATVMHSYDPGHNLRLEHTHCYSDHGDAGHYHYDVTPETVSYEGWFAPASKIYRIDEIK-------- +> +IEEKPLHVPPLSEIQKVLQGALCENFKTVKVKVCPCPDLKAKPFCLVESGLCGNGTLLEVGSPSYLRPLVQRDKLYNIPEIIRRVQGPGRFAVGAGAGPWPIRNSNCEGIFNLSVDK-DDQLTNGSYTATVRGESEECVQEKLPDT--EPRCALLLNLFLSQGLPGEVIGILVKQRICEKNFVDCIRKGLLEHYCDRVVGLGGIFVIKRGCVHQHVMR-DFSKTPLESEEDVNKWLKFYEMPAQLNCLGTLVTKDLDLDLRLEHFHSFSFSNWGGHYHYDTTPDSVEYEAYLNVAERVLRVDRPV-------- +> +-EEKPLYVPPLQELKGVIQSALAKNFENVSVEVGDCPDLKDSFYGLVDSGLGGSPLLLEIGGPPFLLPLVQRSKVYNVKEIVQKA-LPGVLAIGAGAGPFPLRNSNCEGIFNMAIDE-DGNLKNGSYTAKVHGAEEICVLERIPDT--DPRCALLLNLYISRGAPGPVVKVKCNKRIGELNFVECIRKGLESHYKEQCVGMGGIFVLKKGAAHQHVMR-DFSKTPLQTEDELNEWLKFYDMPAQLNAVGTLITHEHDLDLRLQHFHSFSKSNWGGHYHYDTTPDVAEYEAYLNVAERVVRVDRPLETHKVGRD +> +-ESVRLFTSPLEDICSILRKGLEKNFKEVSVSVEECPDLTKAPFNLPAAGLAGSTRIADVGGPPYLVPFADLSKNYDFNELAKLIDLPDSFIVGAGGGPHEIVGMNSEMMPNLRTGT---NADNNSKVSKLSGDG--HELVSLAKD--QACCSLMVNLFACEGAPGKVLKVRARQRIGEENFVSCIRKAITEGFPNKVVGLGGIFRMLSGAAKCHIMP-NFSKIALNNDEEVSNWLKYFEMAAPMIFFSVMVSSDPGLDLRLEHSHGYG-AEYGGHYHYDVTPDTVEYEAYYNLAEVLYRVDKPQNTHNIGK- +> +-EKRDLFTPSLKDVATELNNRLTLYFKTVDVDVVECPDLHQPPYCFAARGLCGQPMLVEVGGPTYLIPKVDRSKVYDFCDIQRVLNINPCYFMGAGAGPFPYTEVNCEGIYNVMIDG--SVVKQRSKISKINVNNGTSEQQDLPNT--ETRFALLANLFVSQGLPGEVLKIHVKERIGCHDFIASIRNCLKDAYSTAVVGLGGVFLMKSGTFRQHVMP-DFATDEIKSEEQLNGWLRFYNMSAPLVAVGTLVTGDMDLDLRLQHFHSSSDHNEAGHYHNDITPETVEYLAYFNIANSVVRIDKPKDSHDMGRD +> +-ESKDLFIPDNKELKEALTIGLKKNFQEVSVDFVECPDLSGAPFNLANSGLCGNATIVEYGGAPYLLPLVQRDKLYDINEICLKICRERQLAVGAGAGPYVLCNSNCEGIFNLAGGL-DGKIVSKSHLALVDKDK-QCERRNIPAS--ETRTALLGNIYLSEGKTGQVLKIHCKKRTGSNNFITQIRESLASHFVDKDIGLGGTFLLKSGKAHQHVMQ-DFSVTPIYTEEELNTWLKFYDMPAPLVAVGTLVTNEMDLDLRLQHFHSFSPSHWGGHYHYDTTPDTVEYEGYFGIGEKLYRIDKPKETHKFGRD +> +--KIVLKTPPLEELSSILCAELKKNFVDVSVDIVDCPNLRAPPFRMSGAGIGNDLRIGEVGGIGNLFPSPKTDKFFNLKKICETCEMPKAFVFGPGAGPFHIVGNNCEMVADADFTT-DHQNNVATKVSRVVPNGKGYEMSTI--D--NADFVLMANLAISDGFPGKVLRVHAAKRNGEMNYPGAIRKALIGYYGNSLISLAGVFLVKKGKVRMHVMP-DFPGCPWETIEEMKEWLKYFEMKAPLVCASVLHSNDIGGKLRLEHTHCYSEHGDAGHYHYDTTPDEVEYEGYFAPAKFIYRIDM---------- +> +-EEKPLHVPPLLELQKVIQGALNANFASVDVNVGPCPDLKDSQFGLVESGLGGRPTLLEAGGPPYLRPLVQREKLYNLKEITRKVQGPGKFAVGPGAGPWPIRNSNCEGIFNFSLNE-EDELKQGSYTATVRGEKEECVLERIPEN--EPRCALILNLFLSEGKPGEVLRISAKQRTGVENFVDCIRKRLEQHYGDKAIGLGGIFVVKKGCVHQHVMR-DFSKTPIHTQEQIQQWLKFYEMPAQLNAVGTLVTKDMGLDLRLQHFHSFSFANWGGHYHYDTTPDIVEYEAYLNVAERVIRVDRPQLTDQLGRD +> +VEEKPLYCPSMNDVAQALKDGLSENFETVEVSVVDCPDLTQKPFSLASQGLGGSPTILEVGGVPFLMPLVNRSKIYDFKDMNKVTGVNPAFIIGAGAGPFTYAGVNSELVANLVVKD--GEVRQLSQIAKLKDESNEFITETLQDS--VTSFALLANLFVSEGKPGKVLRVHCAKRKGKSDFVTAARDSLLKGFPGKAIGVGGTFLINGSKVKQHIMA-DFTTTPLDTEEKVNNWLRFYSMNPPLVALGTFVTNDPGLNLRVIHFHALSDHGEAGHYHYDTEPEKVEYLAYFNLGTKVVRMDRPQDESKLGH- +> +-EEKPLHVPTFEEVQEVLLKELPTNFAEVSVEVVDCPNLSNPPFHLVKPGLNGSPTLIEVGGAPYLLPLVDRSKVYDIEKVARKAVGKDVLAIGAGAGPYMLPGVNCEGIYNVNVKR-DGTLESGSYYSYVKGTEESCQAVKIPHN--EARFALLANIFASEGNPGKVLRVYCKTRTGNQNYIESIRLALAKKYPEQCVGLGGAFLLKSGAAKQHVMR-DFSTTPIHTEEELNTWLKFYNMPAPLVAVGTLVTNEYDLDLRLQHFHSFSKSHWAGHYHIDTTPDYVEYEGYFTFGEKIVRVDKPVNTHKFGRD +> +-EERPLHVPPLSELKRVIQGALDENFQTVDVSVEACPDLRDSQFGLVESGLSGKATLLEAGGPPYLRPLVQRDKLYNLKEITRRAQGAGKFAVGPGAGPWPIRHSNCEGIFNFSLNE-EDELTQGSYTATVRGANEDCVLERIPET--EPRAALILNLFLSEGKPGEVLRISAKQRTGGENFVECIRKGLERHYGDQVVGLGGIFVVRRGCVHQHVMR-DFSKTPIHTQEQIQNWLKFYEMPAQLNAVGTLVTKDMGLDLRLQHFHSFSFANWGGHYHYDTTPDTVEYEAYLNVAERVIRVDRPVATDQLGRD +> +--VIENYVPSLEELKEVFQSSLKLNFETVEVDIVNCPDLSKSPFHQTSSGFGQNLRIAEVGGPGNLYPGFHINHQFDIKTIGKVCEHPEASVFGPGAGPWPVVRQNCEMVADVNLKT----GRVGTRIAEIDTKNEKLYVQRT-ID--VPKFSLMANLALSDAKSSKVVHFKASGRTGQKNVTNCIRDGLQEHFGEKVVSLAGQFIIHSGQAKLHVMP-HFPGCPFENNEEVDKWLNYFTMSAPLVCSTVMHSYDPGHNLRLEHTHCYSDHGDAGHYHYDVTPDSVSYEGWFAPANRIYRIDEVA-------- +> +VEEKSLAQPPLNLIAKAINDGLTKDFEYVQAEVVDCPDLTKAPFHLAAEGLGGSETIVEFGGVPYLMPLVQRDKVYDLKDLIQIIGIDPVFVVGAGAGPHVYVQKNSELVTNISISK--NNIINLSRIAKLKDEQNDFEVEIL-K--EETRCSLLANLYTCQGKSSKVLKIHCKKRIGKNDFVSAVKQTLASTFKDQCIGMGGTFLITGSKAKQHVMP-DFSKTPILNDDQVNEWLRFYEMGPPLVAVGTFVTKDPGLDLRLQHFHSFGTHPEAGHYHIDTNPDTVEYLAYLNTGSKVVRIDRPHETHQVGRD +> +--RIDLTVPSLDRIIEALLPELSKNFETVSVDAVQCPDLTCSPFNLAAEGLNGDEMVIDIGSPSFLLPLVNLDKVYDIRDFMKVTGTDPLFVMGAGAGPWPHVGVNCEFIGNVRLTSD-DSVNNCSHLYKVDPQTGSQVHHRLPQD--ETRFALLANFYTSRGMKGEVLKIVCETRNGPLDFVTSIRQALAKYFGDKPVGLGGVILIETSKVKVHVMP-DFSKTPLHSETDLNNWLKFFEVSTPLVALGYLVSHDPGLDLRPQHFHMFGTHGEGGHYHHDTEPTTVKYTAYFNVAKKLIRVDQPEIALLFGK- +> +-EKRILHLPPLQEVAEVLQAGLRQNFAEVEVVAVDCPDLRE--WGIAGEGLGGNTRLLDVGGPPFLIPTVMREKLYDMRDYPQLTGLSEGMMIGAGAGPWPYINRNSEMMPNLFVKQ-DKTIIQRTHITRTNDEDGSYETLKLPES--ETRNAVLGNLFLCSGEPGKVLKVHCKVRTGEKNFVTCMREVLNAYYGELTVGMGGVFKILQGKVWIHVMP-DFSPCPINTDEDLNNWLKFYEMSSPFTVLSTLISRDPELDLRVEHGHGWGENSQGGHYHYDTTPEEVEYLGYYNLAELCYRVDKPTNTHQLGRD +> +---AILHQPALQEVAGVLEKGLKENFKTVKVEVVDCPDLRD--WGVAGEGLGGSTRLLDIGGVPFLMPTVMRDKLYDMKDYPTLTGLTEGLVIGAGAGPWPFINRNSEMMPNLYVNK-DKSLIQRTHITRTKDEDGSYETLDLPDS--ETRNAVLGNIFISEGKPGKVLKISCSARTGPKNYVTCMREVLGDHYGEKAVGLGGVFKVLQGKIKVHVMP-DFSACPITTDEEVNQWLKFYEINAPFTVLSTLISRDPGLDLRVEHSHGWGEAGTGGHYHYDTTPDQVEYLGYYNTADLCYRVDKPTQTHMIGRD +> +-SKHTLNPPPLEDIATKLQSALAKNYRDSSVVVERCPDLRHAPFHLATQGLSGNERVADVGGQANLFPKPHLECKYSLLDIAKAMEMDLESLVGAGAGPSHIVGQNCELAPNLAWEGGFEKVENRTYVAKIAKDSGEAIVDKC--S--STDCALMVNLFGSSGLPGPVLKITARGRQGSGSFPECIRTALHAAYGAQPVSLGGVFLVKSGKARYHIMP-DFPSAPFENRDDVEEWLTFHNFNAPMVCLTVMHSADPGLGLRMEHTHCFAPRDAGGHYHNDVESEEIEYEAYFNTAKVIYRIDPP--------- +> +-ESKPLFVPPLNEVAKALQDGLSKNFINAEVNAVDCPDLSNAPFNLAAKGMGGKERILDIGGVPYLIPLAQKHKLYDMRDYPSLTEMNEALIIGAGAAPFTYIQRNAEMMPNLTVDHEGKVKTQKTTMARTDDEEETYKLLHLPKE--ESKMSLLGNLFLSEEKPSQVLEIKCRCRSGKQNFVSCISNILRETYPEKCIGLGGVFCAAKGKLKIHVMP-KFSEVPLQTDKDVENWLNFYEMDAPFTCLSVLVSNDPGLDLRLEHSHGFNAQGQGGHYHYDTTPDVIEYTAYYNIAEACYRVDRPNVTHMVGRD +> +--RLETHVPSLEAIADAFRSKLPSNFETVTVDIVECPDLSSAPFNLTSPGFGKNLVIAEVGGPGNLFPTIHKEKAFDITKICSTCEQPRAFAFGPGAGPWPIVGVNCEMVADVNCADN----KVGTRTAKIEGDS--YKVEQI--D--SSTFSLMANLAVSEPQGGRVVHIKAKRRTGKTNFPDSLRQSIVKAFDGKLVSLGGFFVLHSGRAKLHVMP-DFPGC-FETEEEVSQWLRYFEMNAPLVCATVMHSNEGGHKLRVEHTHCYSAHGDGGHYHYDTTPDEVEYEGWFAPASAVYRIDE---------- +> +--VIENYVPSLEELKEVFQKSLDANFETVQVDIVDCPNLSDPPFHQTSSGFGQNLKIAEVGGPGNLYPGFHTDHQFDIRTIGKVCEHPEASVFGPGAGPWPVVKKNCEMVADVNLKT----GKTATKIAEIDENSSEKKYRQKTIE--EPKFSLMANLALSDAKSAKVVHFKASVRTGEKNVTHCIREGLQEHFGERPVSLAGQFIIHTGQAKLHVMP-DFPGCPFANNEEVDKWLNYFTMDAPLVCATVMHSYDPGHNLRLEHTHCYSEHGDAGHYHYDVTPATVAYEGWFAPAGKVYRIDEVA-------- +> +VEEKPLFFPPLENVAEALKVGLSENFETVEVSVVDCPDLTQKPFSLASQGLNGSTTILEVGGVPFLMPLVDRSKVYDFKDMNQVTGVNPAFIVGAGAGPFRHAGVNCELVANLVVKD--GQVSSMSQIAKLKDESNEFVTETLQDS--VSTFALLANLFVSEGKPGKVLRVHCAKRKGKADFVTAARESLLKGFPGKSIGVGGTFLVSGSKVKQHIMA-DFTSTPLDSEEKVDNWLRFYSMSPPLVGLGTFVTNDPGLNLRVIHFHSLSDHGEAGHYHYDTEPEKVEYLAYFNLGAKVVRVDRPQDESKLGH- +> +VKKLALNPPPLSELSQVIGERLSKYFGHVATNIIPCPDLRQPPFHLAGKGLCGNERIADVGGPPHLRPSPRLDKKYSLPSIMQMIEMQQPFVLGAAAGPFHVIGQNSELMPNLARGE-DGEWQNETHYAKVNEDG-QCHLDKVPDD--SKDFGLMANLFASDGLPGDVIHIRAKRRIGDLNFTEAIQDAVKTEYGERPISLGGVFLVRSGTTKLHVMT-DFSPDPCPGPD--HEWFKYYDSSAPLICLTVFHSADSESDLRMEHTHCFSKHGMGGHYHYDTTAEEVEYEAWLNPAKVMYRIDQPG-------- +> +-----------------LANGLKSCFATVNVEVVECPDLSKAPFHLAGSGLNGSPVLVEIGGPPYLLPLVDRTKLYDVVSVAKRALHDDRVVLGAGAGPFPLVGSNCEGMYNLRYTP-PGTVVSESHLAMVTSEQ-EVVVRKIPST--DTRCALLANLLVAEGNAGPVLKVSCKRRTGNKDFIASIRTCLDERYGEQTVGLGGVFLLQAGKAKQHVMS-PFSNAPIHTEEQLNEWLNFYDMPAPLINVGTLVTNECELDLRLQHFHSFSTHGHGGHYHIDTTPEVVEYEGYFVAGERIVRVDKPVNTHKFGRD +> +---YSLEVPSLEDLVDVFRIALEANFRNVAVRIVDCPDLTEPPYGMAAKGISKSTKISDVGGVRYLTPLPQLDHKYDLQTIAKESELSPPFIMGAGCGPYQDVGCNCELMANVAVSS-AGVVKNESRIAKLDKDG-KCQIERL--Q--TTNLAILGNFFLSAGEPGKVVEIRAEGRTGSENFVSILRQAVRARYQEKPVGIGGVFLVEKGSLNIHVMP-DFSKAPLETEGTVDQWLKYFTQPAPMVFMSVFVSEDPGWDLRCEHTHGYGVQNRGGHYHYDTTPDEVEYVGYFGCAETLYRIDRPPS------- +> +--VAEMHVPPLDELAKVVSDGLTAHFKGVVAEVVESPDFREPPFHLAAEGINGSPRLADVGGPPYLVPKVQRHKVYNLTDIADEIKLPGCSFLGAGAGSSRLAGCNCELMPNSNLAT----GEIHTHFAKMKDG--APVLERY--M--SNEFGLLANLLATEGKAGKVLKVSASGRAGDLNFITAIRKVMHAHYGDKPVALGGVFIMDKGQAKLHVMP-DFSETPLTTDEEVENWLHFYHADAPLICLGSCVSHDPGFDLRVEHTHVFSSHGQGGHYHYDVTPVDVEYTGYFVVAEQVVRVDAPKETHQVGRD +> +-TKHQISPPSLDELVGVLTPALQSNFETAKVSVERCPDLRYPPYHLAAPGLSGDECVADIGGQPNLFPEPRLECKYSLIEIAKEMDMDPDHLLGAGAGPFHRIGLNSELAPNLSWGNNFEQVVNQTYYTKIDDSNRAAVCERS--P--TTDCALMMNLYGSSGLPGNVIKITARARTGNKSFTECIRKTLAENYGDRPISMGGIFLIKTGKAHFHVMP-DFPPKPFKNAKQLNEWLTYHDFEAPIVCLTVFHSADPGKGLRMEHTHCFSTHNRGGHYHYDLPVGEIEYEAYFNTAKTIYRIDKPEVTLE---- +> +----------------VLQDGLTKNFSHATVTVVECPDFRQPPWNFPATG--KNLLIVDVGGPAYLLPLPQLNKIYDMNDVAAKADLPGGYVIGAGAGSHTSVGVNCEMIANVCTGTETSNPVIQSKITKVNPEDGSCVFQDY--D--VCDFSLLANCLITEGKPGKVLKVEASKRTGDENFVTCMRLALGSYYGNRAVGIGGTFMIAKGKANFHIMP-EFSKTPLNSPEEVNNWLKFYDMSAPLVCLGVLESYDPGLDLRVEHFHGYNNHGEGGHYHYDTTPNEVEYVGYFTPAERLYRMDRPPK------- +> +-SKYTLTPPPLEDLATRLQSALAKNYGHSSVTVSQCPDLRLPPFYLATQGLSSNECIADVGGQANLFPKPRLECKYSLLEIAKAMEMGPESLIGAGAGPFHVVGQNCELAPTLSWKGSFENIENRTYVAKIAKDSGEAIVSKY--P--STDCALMVNLFGSSGLPGPVLKITARGRQGSGSFPKCIRTALHEAYGSKPVSLGGVFLVKSGKARYHIMP-DFPSKPFGSRDDVEDWLAYHTFAAPMVCLTVMHSADPGLGLRMEHTHCFAPRNAGGHYHNDVESEEIEYEAYFNTAKAIYRIDAP--------- +> +--RMDLNVPSLDRIIEALLPELSKNFETVSVDTVQCPNLTCPPFNLAAEGLNGDETVIDIGSPSFLLPLVNLNKVYDIRDFTKITKTDPLFVIGAGAGPWPHAGVNCEFIGNVQLTSKNNVNNNCSHLYKVDLQTENQVHNRLPQD--EMRFTLLANFFTSHGFKGEVLRIVCETRNGPLDFVTSIRLALAKYFGNKPVGLGGVILIETSKVKVHVMR-DFSKTPLHSETDLNNWLKFFEVDTPLVGVGYLVSHDPDLDLRPQHFHLFSNHGVGGHYHYDTEPTTVKYTAYLNVAKKLIRIDQPEIAPLFGK- +> +VEEKPLDIPSLKNIAEALQEGLSKNFVNVEVSVEDCPDLTKAPFLLAEKGLGGSPTIVEVGRVPYLMPLVNRSKIYDFKDMNLLTGVDPAFIIGAGAGPFLHATVNCELIANVVVKDN-QLSIQKTQIAKLKDESNEFVAEKLPDS--ESTYALMGNLFVSKGETGQVVKVKVSKRKGKSDFVSAARDSLVGGFPGKSIGVGGVFLTTNSKVKLHIMP-DFSKTALETEDQINSWLRFYEMNPPLVSVGTFVTNDPGLNLRLIHFHTFSEHGHAGHYHYDLDPDNVEYLAYFNLGAKVVRIDRPLEESKLGH- +> +--RSTLFTPTLDVLAIALKDGLNLNFKDVEVNVVTCPDLRNEPFDLASEGLGGKPRLLDIGGVPYLVPLAQKNKLYELKDVPKMTDFADCLIMGAGAAPWTHLKRNAEGMYNLLLKG-DGSIVQKTHIARTHDEDDRCELLALPET--ETKLSLLGNLFLSNGAKGPVLEVRCKGRSGPENFVSQMRKTLADAFPSKSVGLGGIFCVQKGQVKIHVMP-EYSEKPLKSDADVENWLKFYKMDAPYTCLSFLVSRDPGLDLRIEHTHGQNEKCQGGHYHCDTTAETVEYHGYFSLAEYVYRVDRPKVTHQIGRD +> +-TQHKLSPPSLSELAEVITPALEANFSEAKVSVSPCPDLRQAPYYLATEGLSGNEKVADIGGQPNLFPEPRLECKYDMLQIAQEMQMESKQLLGAGAGPFHHVGVNSELAPNLSWQDNFDNVKNLTYYTKFDGAEG--KHAAICAPSPSCDCALMMNLYGSNGAPGDVLKVTARSRKGEKSFTECIRRALAEKYGERPISIGGMFLLKKGKAHFHVMP-GFEAKPFPDAKQLNDWLTYHDFEAPIVCLSVFHSADPGKGLRMEHTHCFTTSNRGGHYHYDLPPGEVEYEAYFNTAKTLYRIDKPEVTLE---- +> +ITKHHLSPPSLAELADVLTPALQANFEHAHVQVEPCPDLRKPPYHLATEGLCGGETVADIGGQPNLFPEPRLDCKYSLLDIAKAMDMSPHQLLGAGAGPFHRIGVNSELSPNLSWEGSFENVKNLTYYTKYDGTNHAASCERS--P--TSDCAFMMNLFGSSGLPGDVLKITARARKGEKSFTECIRRTLAETYGAQPISMGGMFLIKQGHAYFHVMP-DFPAKPFKDAKQLNEWLTYHTFEAPIVCLTVFHSADPGKDLRMEHTHCFSEGDRGGHYHYDLPPGEIEYEAYFNTAKTLYRIDKPDV------- +> +-DKHSLHRPSLEEVAKALSDGLRSNFEHVQVDVVDCPDLRQKPFMLASEGICGQPRLTDIGGVPYLVPIAQTDKVR-VDLSLQDPERKHLSYFFLSAGKMHTVSVHLRQIYLCIYQSTGKPFFFIYWCNSFV-QDGSCVLGNLSGP--CCEFCLMGNFLISEGKQGKVIKVSAKKRTGQENFVTAMRNGLKAKYGTEPVGMGGAFLLAQGKAKLHIMP-KFSTAPLLTDAAMNQWLKFFEMNAPLVCLSTFVSHDPGWDLRIEHTHCFSDHKQGGHYHYDTTPDEVEYLGYFNVAEWLYRIDAPVSTHKIGRD +> +VKKVPLCPPSLSALAESISVGLSSNFTHSSCTVSTPPDLSLPPYHLASPGLTGSPRVVDVGGPPNLSPAPDLTKKYDLLSIAQQAEMSTAFMLGAGAGPFHVVGQNSELMPNLAYGASLHDVRNRTHYAKIKPDD-SVCCARIPDS--STAFALMCNLFCSDGSPGPCLHVTGKARNGPLNFTQAMQDALKASFGNRLISIGGVFLIKKGAAKLHVMP-DFPSEPFKSRDDVDKWLRYFDMHGPLVCLTVFHSGDDGGALRMEHTHCFTVTTKGGHYHYDLDDTEIEYEGWFNVAEYLYRLDQPG-------- +> +VKKVALSPPSLASLAEAIASGLSSNFAVSSCSMATPPDLTAAPYHLAGPGLGGSTRIVDVGGPPNLAPSPNLTKKYDLAAIARQVDMSPSFLLGAGAGPFYVLGQNSELMPNFAYGTAADSVRNRTHYAKITAAD-TVCCAPIPQE--STGFAFMCNLFCSDGVPCECLHVTARSRSGPLNFTATIQHALQAAFGDKLISLGGVFLINKGTAKLHVMP-DFPTQPFTSRADVDRWLRYFDMEPPLVCLSVLHSGHDGLALRMEHTHCFTVTTKGGHYHYDLDETEIEYEGWFNVAELLYRVDQPG-------- +> +-TKYPLSPPSLEELADNLQAPLAANYEHSSVSIVQCPDLRQAPFHLASEGLSGNEKIADIGGQGHLFPRPLLDRIYTMDKIAEAMDMSPSSLIGAGAGPFHRVGRNCELSPNISWKQGYENVDNKTCFAQISPNTGDVSIKKS--P--SLECALMANLYGSESEPGPVIKITARKRRGQRSFTECIRKALVAAFGLKTISLGGAFLIKTGKARYHVMP-DFPPDPFKDSRQLNDWLTYHDFDGPIVCMTVLHSSDPGKGLRMEHTHGYSPGDCGGHYHYDVDGDNIEYEGYFNTAKAIYRIDMPSVR------ +> +VKKVPLFPPSLSTLAESISAGLSSNFRHSSCTVSTPPDLTLPPYHLAAPGLTGSPRIVDIGGPPNLSPAPDLTKKYDLLSVAHQAEMSTSFMLGAGAGPFHVVGQNSELMPNFAYGTDLRDVRNRTHYAKIKPDE-SVCCARIPND--STAFALMCNLFCSDGLPGPCLHVTSKSRNGPLNFTQTIQGALKSSFGDRLISIGGVFLIKRGTAKLHVMP-DFPSEPFKSRDDVDKWLRYFDMHGPLVCLTVLHSGDDGLALRMEHTHCFTVTTKGGHYHYDLDDTEIEYEGWFNVARYLYRLDQPG-------- +> +-KNLALNPPPLSELGQVIGERLSRHFGHVVANVVPCPDLRQPPFHLAGEGLCGNERIADIGGPPHLRPSPRLDKKYSLPNIMGVIETGQQFVLGAAAGPFHIIGQNSELMPNLARGP-DGEWQNETHYAKVNEEG-QCQLAKVPDD--SKDFGLMANLFASDGLPGEVIHVRAKRRTGDLNFTEAIQDALKTEYGGRPISIGGVFLVRSGRTKLHVMT-DFSPDPCPGPD--HEWFKYYDSSAPLICLTVFHSADSEGDLRMEHAHCFSTHGMGGHYHYDTTAEEVEYEAWLNTAKLLYRIDQPG-------- +> +--VIECHTPSLDELKQVFETSLRENFQHVQVDIVKCPDTSEPPFEMTSTGFGKDMRIAEVGGPGNIYPVVRKENQFSFEKIAEVCQLPDGHVMGPGAGPWPIIGVNCEMVADANCAVN----QFETRVIKIDESTKGYELSRT--S--EPTFNLLANLAISKPRSSDVVHFKCSVRTGKKNLPETIRQGLATKFGNTPVSMAGVFILDNGKAKIHVMP-DFPSCAWGHEKEVNEWLRFFEMPGPLVNVSVIHSYDPGHKLRLEHTHCYSSQGDGGHYHYDVSPETVSYEGWFAPAQKIYRIDE---------- +> +-QEKETHKPSLDEIRNVLEEALKKNFNEVSVEIVDNPDLKSEPFYLASSGISGNPLIIEYGNDDYLLPLVDKSKVYNLIPTIREIETYKEYVCGAGAGPFPLYDQNCEGIYNMKVFK-NGTIDNQSHIARTQGS--GTETLKLPNN--ETRAALLGNLFLSEGNDGKVLKVIAKNRTGEENFISAMRLGLSEKYSDEVVGLGGVFVMKKGIANIHVMD-RFSENPINTDEELNNWLTFHEMPAPLIALGNFVSHQTDFKLRYHHFHCFSKHNHGGHYHYDVTPDIVEYEGYFNIAERIILIDKS--------- +> +VKKLALNPPPLCELSQVIGERLSRNFGHVVANVVPCPDLRQPPFYLAGEGLCGSECIADVGGPPHLRPCPRLDKKYSLPTIMRMIETRQRFVLGAAAGPFHVVGQNSELMPNLARGH-DGEWLNETHYAKVNEEG-QCHLAKVPDD--SKDFGLMANLFASEGLPGDVIHIRAKGRTGGLNFTEAIQHALKTEYGAQPISIGGVFLVRSGKTKLHVMT-DFSRDPCPGPD--HEWFKFYDSSAPLICLTVFHSVDSESDLRMEHTHCFSTHGMGGHYHYDTTAEEVEYEAWLNTAKLLYRIDQPG-------- +> +---INTLKPSNNELRSVIETILWKNFKNVQVEVASSPDLTAAPFRMTSNGFGKNLVIAEVGGMGNLYPDLHKEKQYDIQEICEKCGAPKAFVFGPGACPSRVIGA-GELVADANLSEN----KVTSKVTTLVKNHLKYKTKII--N--STKFSLMGNLVVSEQGPSEVVHVKCSERTGEDSLPGCIRKGMAEHYGQSCVSLAGIFLLLRGKADVHIIP-DYPEKPFNSMDEVEKWFQIFNVSAPLVCASVLHSYDPGYKLRIQHTHCYSDHDDAGHFYNDTTPKIAEYEGWFTAAEKIYRIDE---------- +> +-EKLELRTVGLDDIATVFQAALEANFTEVSVAVVDCPDLTLPPYRMAARGLSGSTKIADVGGVRYLTPTPQLDHIYSLRDVGKLTGSNDGFVIGAGAGPFQETGCNCELMADAFISTEADHSKIVSQTAKLNKDG-KCVVTSL--T--TPSLAILGNFFVSKGEPGKVIEIRAKRRTGADDLIACLRKSLARQFGGTPVGVGGVFLVQKGRVNIHVMP-DFSKTPLATQDEVDKWLQYFEFPAPMIFQSVFVSEDPGLDLRLEHSHGHSLHSHGGHYHYDTTPDEVEYVGFFNAAEALYRIDRPK-------- +> +-TSKEIPPPPLEDIRVALEKALSENYKEAQVEIVDCPNLTEAPFGLAAPGLGGKTALADVGGVPYLVPGPALERVYNLDHTASQVDIPGALVIGAGAGSKHDVGVNSELIPNIRTRGGENKRRNLTHCSRIDPADSKSLLLRYEEDLNSADFTLLGNLFFSEGKSSKVLKVTTKTRTGTGSIVTCMRKGLAEAFS-VPVGMGGTFLQAAGTVKYHVMP-EFSACPLDSDDKVNAWLRYFNFEAPFVNMATFISKDPDLDLRVEHTHGYSTNQTGGHYHYDVTPETIEYVGYFTPAQKIYRIDAPTETHMIGRD +> +IKKVELAPPSLSALAQGIVSGLCSNFSISDCSVAIPPDLTAAPYHLAGSGLSGSPRIVDVGGPPNLSPTPNMTKKYDLTAIAGQVDMSPAFMLGAGAGPFYVLGQNSELMPNFAYGTGEDVVRNRTHYAKITPSD-TVCCAQIPQA--STGFAFMCNLFCSDGVPGPCLHVTARSRTGPLNFTESIQHGLQATFGDKLISLGGVFLIKKGKARLHVMP-DFPTQPFNSRADVERWLRYFDMDGPLVCLSVLHSGDDGLGLRMEHTHCFTVTTKGGHYHYDLDETEIEYEGWFNVAETLYRVDQPGI------- +> +-RKYPLSPPTLSELAETLKVPLSTNYDHSTVRVITCPDLRNAPFHLATPGISGDEKIADVGGQANLFPRPRLDKIYSMPELAKAMEMGSEGLLGAGAGPFHVIGRNCELAPNFSWEGGFENVDNRTRVIQIRPDTGGVGVGVS--P--SVDCALMVNLYGSLGETGEVIRITARKRRGAKSFTECIQTALKEAYGSQTISLGGVFVVRSGKARYHVMP-DFPPEPFKNRKQLEEWLTYHDFGSPMVCLSVLHSADPKLGLRMEHTHCFSEENTGGHYHYNLKDEEVEYEGYFNAAKVLYRVDAA--------- +> +-QKISLSPPTLSELAEKLQGSLSANYERSSVTVVPCPDLREPPFLLAHEGLSGDEKVADVGGQTHLYPRPMRDKTYALISISREMEIEHEMIIGAGAGSSDIVGQNCEMAINFGWRYQGSWRHNGGRYVKIEPGTDSVLLEKTDSA--RWWFGLMGNLFASDGGPGDVLKITARKRVGEGSFTECIRKALHAAYGSQIVSLGGVFVIKSGKARYHIMP-DFPPEPFRDRQRFNDWLTYHDFKGPMTCLTVLHSVDPKLGLRMEHTHAFSTENAGGHYHYDVEEEEIEYEGYFNTAKALYRIDKPEFS------ +> +-EKAQLHIPSLQELCTVLQAGLESNFAEAQVNVVECPDLTQKPFCFPVPGLCGSPRITDVGGVPYLVPVVQKHKEYNMNTVSKELELPGAFILGAGAVSSRAVGMNAELIPLVLTETEKRAEVNSSYVASINPADGQCLQEKYSDKFSDCNFGLLANLYACEGKPGKVLEVRAKRRTGEHSLVTALRKSLEGHYPDKSLALGGTFIIQKGKAKIHIMPREFAVCPLNTNDEINSWLKHFEVTSPLICQSVLVSKDPGLDLRVEHTHCFSPHGEGGHYYIDTTPDT---------------------------- +> +-ARYPLSPPGLEELAKVLEAPLAANYEHIAISVVECPDLRAAPFNLATTGLSGNEKISDVGGQSNLFPSPRLDTIWSMKELAQAMEMDPDSIIGAGAGPFHQVGRNCELAPNFSWGKDFGDVDNRTHIAKIDKDTGAPRVEKS--P--TLDCALMINLFGSEGKTGPVLKITARKRKGPSSFTQCIRKGLRTAYGKQTVSLGGAFIVKSGRTNYHIMP-DFPPAPFKDPKQLNDWLTYHDFDSPMVCLSVLHSADPEQGLRLEHTHCFSPNNSGGHYHHDIEGLEIEYEGYFNTAKMIYRMERPSVTLA---- +> +--HKPLCQPPLKYVAAVLEAGLKENFAEATVTVEECPDLRQAPWGLAGPGLGGETRVMDIGGVPFLMPLVQREKLYDMADYPKMAGLKEGLVIGAGAGPWPFLNRNAEMMPNLFVKA-DGTILQETHISRTHDEDGSFSTIKLPKE--ETRNSLLGNLFISSGEPGPVLKIHCKGRTGPKNLVTCMREILAEAWPSESLGLGGIFRIVSGKAKFHVMP-DFSPCPINTDAEVNQWLKFYEMDAPLNVLSVLVSRDPGLDLRVEHSHGWGENSQGGHYHYDTTPDDVEYIGYYNTAELCC-------------- +> +-TTHPRDPPPLGELAAIIQRSLQANFASASVSVVECPDLRQPPFHLASSGLSGNPCIADVGGQPNLFPRPNFDAKFNLRSLAKDMQMTEGFLIGAGAAPFHETGYNAELAVNLYTPPDIDQVRNGSRIIQVNQDG-SSCCEVI--K--SLDCGLMVNLFGSSGDTGPVLKITARTRTGEQNFTNCIRLGLADHYGSRPISLGGVFILKAGKAKFHIMP-DFPKEPFRDREQLKEWLTYHDFEAPVICLTVMHSSDPRLGLRMEHTHCFEENRKGGHYHYDLQDGEVEYEAYLNVASTVYRIDRPE-------- +> +--CFILQPPPLEELRDVIQNGLRNAFETAFVEVTTCPDLSQSPFHLSAPGLCGDEKIADVGGPAYLQPVSDLTKKYTIPKILDLVGMEGQFAIGAAGGPFHVVGKNSELVPNLARDA-NGKWQNLSRYVHIDDDE-KMNLSMVPKD--TKDCGLMANLFISRGHQGESLHIRAKGRRGQLNFPETIQELLRVNYGGRPVSLGGVFLVKQGKAKLHVMT-DFSTSSCPGPD--HEWFRYYEADAPIVCLTAFHSVDYDWNLRMEHTHCFSESGVGGHYHYDTTPDDVEYEAWLNTAKAVYRIDQP--------- +> +-TQHSLSPPALEELVNVLAPALDANFEMAKVSVEPCPDLRKAPYYLATEGISGEERVADIGGQPNLFPEPRLECKYSLVSIAKEMQMSSEQLLGAGAGPFHDIGMNSELAPNLSWEGSFDIVKNLTYYTKFVGSNHATVCEQS--P--SADCALMMNLYGSSGKPGSILKITARSRKGDKSFTECIRRALADKYGERPVSMGGMFLIKTGKAHFHVMP-DFPATPFKDPKQLNDWLTYHDFEAPIVCLTVFHSADPGKGLRMEHTHCFSDGGRGGHYHYDLMAGEVEYEAYFNVAKTLYRIDKPEVTLE---- +> +-TSHTLSPPSLEELAQVLSPALKANFKTSSVTVERCPDLRKPPYHLATEGLSGQESVADIGGQPNLFPQPRLECKYSLLEIAKEMEMSGSQLLGAGAGPFHVIGMNSELSPNLSWEKSFDNVNNLTYYTKIEEDH-GKPIARCEKS-PCADCALMMNLYGSTGNSGPVLKITARTRTGSKSFTECIRRALFDKYGAHPISIGGVFVMKTGKAQFHVMP-DFPPAPWTQGSQVNDWLTWHEFIAPIVCLTVFHSADPGKGLRMEHTHCFTDSNQGGHYHHDLDVGEVEYEAYFNAAKMLYRIDKPEVTLE---- +> +-ERFILSPPTLEELAEIISGPLSSNFEFANVEVVQCPDLRRAPFNLATEGLSGNERIADVGGQPNLFPSPRLDNIWNMRDLAKAMDMDPNSLIGAGAGPFHQVGRNCELVPNLSWDGNLATIDNQSYLAQIITDTGEVSVERS--P--SLDCALMVNLYGSSGLPGPVLKITARKRKGQKSFTECIRKAVTAAYGSRPVSLGGAFLVKTGKAFFHVMP-DFPPKPFESRKQVDNWLTYHDFEAPVVCLCVMHSADPGKDLRIEHTHAFSQANAGGHYHYEADGSDIEYEGYFNTASVIYRIARPES------- +> +IEKFPLSPPGLEELVAKLQAPLAANYEHSTVNVVSCPDLRQAPYHLATEGLSGDEKIADVGGQPNLFPRPKMDCVWSMTELAEAMDMNPAGLLGAGAGPHPVIGQNCELAPNIGWQGSFENVKNESRYAKIDKETSAVHVDKS--P--SLDCALMINLFGSSGSPGPVIKITARKRTGSRSFAECIRKGLRLAYGEQTVSLGGLFLVKKGKAKYHIMP-DFPTEPFNNRKDVDSWLTFHDFDARMLCLSVLHSADREGGLRIEHTHCYAAKNAGGHYHYDLDDTDIEYEAYFNTAKMIYRLDRP--------- +> +IETIQLNEINLDELSNRLLDGLRNKFEHCSVSVVDCPDLTRPPFNLAASGLCGRTAIADVGGVPYLLPLVKRDKIYSFKQIANIVDPGQQFILGASAGPFHKIGHNSELMPNVLLEKEGFKIRNDTHLAEIHDQNNRFRLLKS--D--HSEFGLLGDLFVSEGKPGKVLRIEVQNRKIKASFTTIIRKILQESYPNQLISLGGVFLIEQGEAILHIMP-DFSDVPLNTEQEVNDWLRFFPMKSPLRCLTTMHSVVDGYNLRSEHTHCFSDHNQGGHYHNDIDPKRIKYLAYLNTAKIIYRIDKPSITN----- +> +IQKFQLSPPSLEELAERLKSPLAANFHFSSVTVEVCPDLRQAPFHLATRGLSGDERVADIGGQPNLFPRPQLDKFWAMDELAVAMDMNNTSLIGAGAGPFHVIGQNSELAPNLNWEDGLQTINNQTRIIKIMKTTGDIGVEKS--S--SLDCGLMANLFGCSGESGPVLRVVARGRKGVRSFTECIRKALHSAYGDHAVSLGGAFVVKSGKAVYHIMP-DFPPKPFRDRGQVDAWLTWHEFQAPMVCLSVLHSADPGKGLRMEHTHCFSEGNAGGHYHYETDHSDVEYEGYFNTAKVIYRIDNPT-------- +> +-KKATLSPPTLPSLASAIAAGLCSNFAQSSCSVATPPDLTLKPFHLAASGLAGATRVVDVGGPPHLQPTPDLSKEYDLLSISQQVGMNQSFMLGAGAGPFHVLGQNSELMPNFAYGTGSDQTRNRTHYAKITSSN-DVACCQL-PD--STGFGLMCNLFCSDGLPGPCLHITAKSRVGPLNFTETIQDALKSTFGDQLISLGGVFLIKQGKANLHVMP-DFLSRPFGSRKEVEEWLRYFDMEDPLICLSVLHSGNDGGDLRMEHTHCFTVTEKGGHYHYDLESTEIEYEGWFNVAELLYRVDQP--------- +> +VKKVELSPPSLASLADAIASGLSSNFAVSSCTVSTPPDLTHAPYHLAGPGLGGSPRIVEVGGPPNLSPSPNLTKRYDLAAIARQADMSPTFLLGAGAGPFDVLGQNAELMPNYAYGAGVEVVRNRTHYAKITPAD-TVCCAPIPHA--NTGFAFMCNLFCCDGVPVECLHVTARTRTGPLNFTATIQHALRAAFGQQLISLGGVFLIKKGTAKLHVMP-DFPAQPFTSRADLERWLRYFDMTGPLVCLSVLHSGHDGLGLRMEHTHCFTVTTKGGHYHYDLDETEIEYEGWFNVAECVYRVDQP--------- +> +VEKFPLSPPSLHDLAEQLGGPLRENYEDATVSVVDCPDLRQPPFHLCTEGLCGDEKISDVGGQPNLFPQPRLDSTWSMTDLARAMEMSAHGLIGAGAGPFHVVGQNCELAPNLSWKDKIENITNQSRLARIVPETNAVSLEKS--P--SPDCGLMVNLYGSLGQPGPILKITAKGRKGSTSFTECIRQGLAAAFGEETISLGGVFVVKSGKALYHIMP-EFPSEPFKDRQQVDDWLTYHDFDSPMVCLSVFHSADPNNALRIEHTHCFSATNAGGHYHHESTGAAIEYEAYFNTAKMIYRIDRP--------- +> +---INTLKPSNNELRSVIENALWKNYKNVQVTVDTSPDLSKPPFRMTANGFGKKLSIAEVGGMGNLLPILRKDKLYNTE-------KKSAFVFGPCASPASIVGATGEFIIDANFATS----KVAGKVTIQQKGH-TSPYKMLIFD--TPKFDLMANLAISEEGPGEVVHVKCSERKGEDNLPGCIRKELARHYGPSCVSLAGIFLLLQGKADVHIVP-DYPTDNFKSMDEVRKWFHMFNVKAPLVCATVFHSYDPGHNLRMEHTHCYSDHNDGGHYHTDTTPDTVAYEGWFTAAEKIYRVDQ---------- +> +---VALSPPSPSALAEAIASGLSSNFAYSSCTLAIPPDLTAAPYHLAGPGLTGSPRVVDVGGPPNLSPTPDLTRKYDLASIARQVDMSPSFMLGAGAGPFYVLGQNSELMPNFAYGTGASSVRNRTHYAKITASD-TVCCARIPDD--STGFAFMCNLFCSDGVPGECLHMTARSRTGPLNFTATIQRALRASFGDKLVSLGGVFLIKKGTAKLHVMP-DFPARPFASRADVDKWLRYFDMDGPLVCLSVLHSGHDGLALRMEHTHCFTVTTKGGHYHYDLDKTEIEYEGWFNVAEYLYRVDQPGTRH----- +> +VEKFPLSPPSLEELAERLKAPLDANYKHASVSVVNCPDLRKAPFHLATEGLSGDEKIVDVGGQPNLFPRPRLDSIWSLPEIGKKMEMSPESLIGAGAGPFHVIGQNSELAPNLSWQGGLDKVDNKSQVIQIKRATGEVSVGTS--P--SVDCGLMVNLYGSLGEPGPVLKITAKGRKGSRSFTECIRKGLNAAYGERTVSLGGAFVVKAGKATYHIMP-DFPAEPFKDRKEVEKWLTFHDFDSPIVGLSVLHSADPGNGLRIEHTHAFSPKNAGGHYHYEAEGEIIEYEGYFNTAKAIYRIDSPADTK----- +> +-SIYPRDPPSLLDLAEVIQRSLQFNFTEASVGVEQCPDLREEPFGLAAPGISGNPCIADIGGQPNLFPTPNFNAQYSLLELATDMQISGGSLIGAGAAPFQDIGHNAELAPNISWKPSTLEIRNNTRIIEVNDEK-LPSCDGT----SSTNCALMANIYGSNGQPGLVLKVKARGRIGDQNFTNCIRHGLRDTYGSRPISLGGVFLLKKGKAKFHVMP-DFPSKPFRDREQLKEWLTYHVFKAPIVCLTVFHSADPELDLRMEHTHCFDADKKGGHYHYDIQEDEVEYEAYLHPASTIYRIDRPA-------- +> +--VHPLSPPPLDELARVLTSALEENYAYASATVVDCPDLSLSPFYLAGSGLCGCECVADIGGQPHLFPRPKLDKKYSLIECARDMKMNPEMLIGAGAGPFHVIGGNSELASNLSWSGGFNNVQNLTRFAKINGTA-EIMVRKS--P--STDCALMMNLFGSSGHSGHVLKIMAKSRRGSKSFTECIRRALNNTYGSTQISMGGVFLIRKGKALFHIMP-DFPNEPFKDRHDLNRWLTYHGFSAPIVCLTVFHSADPESGLRMEHTHCFSEKNEGGHYHHDLPPDEIEYEAYLNTAKTLYRIDQPET------- +> +-RKVALSPPSLTSLADAIAAGLASNFAVSSCTVATPPDLTAAPYHLAGPGLTGSPRIVDVGGPPHLSPTPNLAKRYDLAAIAQQVDMSPSFMLGAGAGPFYVLGQNSELMPNFAYGTGESSVRNRTHYAKITAAD-TVCCAPVPQG--STGFAFMCNLFCSDGVPGACLHVKARSRTGPLNLTATIQRALTAAFGDTLVSLGGVFLIKHGTAKLHVMP-DFPPRPFGSRADVDRWLRYFDMTGPLVCLSVLHSGHDGLALRMEHTHCFTVTTKGGHYHYDLDETEIDYEGWFNVAEFLYRIDQPG-------- +> +VEKFPLSPPSLEELAEELKAPLAANYEHASVSVVQCPDLRNAPFHLAAEGLSGDKKIADVGGQPNLFPRPRLDSIWSLPEISRHMEMSSESLIGAGAGPFHVIGQNSELAPNLSWQGGLDHVNNQSQVIQIKRDTGAVSVGTS--P--SVDCGLMANLYGSLGEPGPVLKITAKGRKGPKSFTECIRKGLNAAYGDRTISLGGAFVVKAGKTIYHIMP-DFPSEPFKDRTEVEKWLTFHGFDSPIVGLSVLHSADPGNELRMEHTHAFSPKNAGGHYHYEAEDEIIEYEGYFNTARVIYRVDRPATTA----- +> +VEKFPLSPPSLEELAEQLKAPLAANYKHASVSVVRCPDLRNAPFHLATEGLSGDEKIADVGGQPNLFPRPRLDTIWSLPDIGRHMEMSPESLIGAGAGPFHVIGQNSELAPNLSWSGGIDRVDNQSRVIQIERGTGAVRVGTS--P--SVDCGLMVNLYGCLGEPGPVLKITAKGRKGPKSFTECIRKGLHAAYGDRTISLGGAFVVKAGKATYHIMP-DFPPEPFKDRKEVEKWLTFHDFDSPVVGLSVLHSADPGNGLRIEHTHAFSPKNAGGHYHFEAKGEVIEYEGYFNTAKTIYRVDNPNAS------ +> +IEKRSLLPPSLTELAHQLAPFLSANFTHAAVTVAPCPDLRKAPFYLACEGLSGNAKIADIGGQPNLFPRPRLDRIWAMDEVAKAMEMSPEGLIGAGAGPFHILGQNSELAPNLGWRDGLDNIINETRLIKILPGTGRVRVEKS--P--SLDCGLMANLYGSLGRTGPVIKITASGRKGDQSFTECIRMALRAAYGERQVSLGGVFLVKSGRAVYHVMP-DFPEEPFKDRSDVDNWLTWHTFDAPVVCLSVFHSADPHNNLRMEHTHCFSGQHVGGHYHYEAEGSAIEYEGYFHTAEAIYRIDAPAELG----- +> +-TTYPLSPPSLDEIAGILRPALEANFQKATISVSQCPDLRKAPFHLAAEXLSGNESIADIGGQPNLFPEPRFECKYNLLDIAKEMKMSPEQLLGAGAGPFHVIGINSELSPNLSWEDSFENVNNLTYYTKFDGTKHAAICERS--P--SSDCALMMNLYGSSGLPGPVLKITARARKGDKSFTECIQQALYXAFRDRPISMGGMFLIKTGTAHFHVMP-DFPPKPFKNAKQLNDWLTYHDFKAPIVCLSVFHTADPGKGLRMEHTHCFSTSGSGGHYHYDLPAGEVEYEGYFNVAKTLHRIDRPVVTLE---- +> +-TITPRNPPPLSELAPIIERALSQNFTHASASVTPCPDLRNAPFGLAARGLCGAPRIADVGGQPNLFPTPNFDAKFDLLALARDMQMDPAFVLGAGAAPFQDIGHNAELAPNLAWRGDSLHVTNGTRVVEVLQSNSTFGEAIKCRPSPSTNCALMVNLFGSSGDPGLVLKVTARTRTGVENFTNTIRAGLLQAYGSRPVSLGGVFLLKSGRAKFHVMP-DFPPAPFKDRKLLQEWLRYQTCEAPVVCLTVFHSADPENGLRMEHTHCFDLDEKGGHYHYDVEGEDVEYEAYLNVAQSVYRINRP--------- +> +--RVLLQPPSLNEVAAAVHNGLGSNFGTWSASVSTPPDLRQPPFHLAGRGLSGNPRVADIGGQSNLFPEVNLDKRYDLLKLSKQMEMTSGVLIGAGAGPFFDLGRNIELMPNIAFGASDGDVSNCTRYAKVLDDG-SALCEKI-GT--STGCGLMCNVFGCDGETGSLLHVKAKGRTGKLNFTEAIQKGLADTYGDRLISLGGVFVVCSGKLKMHVMP-DFPDEPLTSRQDVDQWLHWYDMDSPMVCLSVLHSGDDGLGLRKEHTHCFGASRRGGHYHFDLDETTVEYEGWFNVAEILYKID----------- +> +-TKHLRDPPPLEELAAVIEKALLSNFKTASATVAECPDLKQPPFHLAASGLSGSPRIADIGGQQHLFPRPILNAKYSLLSLAQDMEMSPMFLLGAGAAPFQDIGQNAELAPNLSWRSSLLTFDNGTRVIKVQGDRDQTPVCDR---TSSTNCALMVNLFGSDGDTGPVLKINAKARKGEENFTDCIRYGLQKVYGSKPISLGGVFLLKSGKARFHIMP-DFPPEPYRDRKQLTEWLSYHIFQAPIVCLTVMHSSDPGLGLRMEHTHCFGVNPKGGHYHYDIQDGEVEYEAYFNVASVVYRVDRP--------- +> +-QKRELSPPPLDELAGIIAAGLESNFEQSSVQVEPCTDLRKAPFYLAGEGLNGSTRVGDVGGPPHLAPP-DFSKKYDFMEISKLMEMPQEFLLGAGAGPFYVLGCNAELIPNISYEN--GEITNLTHYAKIAKDD-QVECQKI---ETSTGFAFMANLFGSEGLPGPALHIKASSRKGAPNFTETIQAAVQEKYGDKLVSLGGVFVIKRGRANLHVMG-DFPEKPLQ-RQDVDDWLRRFEFDAPLICLSVLHTGDDGMALRPEHTHCFSGGKNGGHYHFDVEDTDVEYEAWYNVAEAVFRIDSPGR------- +> +-QKFTLSPPTLEELAEPLSAALRANYEHAAVSVIPCPDLRNPPLCLATEGICGDEKISDIGGQPNLFPRPQLTSRYSLPEIAQAMELHHHGLIGAGAGPFHIVGQNCELSPNLSWTAGLDSIDNRTHFAHIDRATGAVGVDKS--P--SLDCALMANLYGSRGEPGPVLKITARKRKQHRSFTECIRKGLRVAYGSRTVSLGGVFVIRSGSARYHVMP-DFPAEPFKDFEHHNDWLTYHDFAAPMVCYSVLHSADPKLGLRLEHTHGYCPRQAGGHYHYEVEGDEIEYEGYFNVAKTIYRVDRPAVTLD---- +> +VEEKPLFVPPLEDVVRTLQDGLPSYFHSVSVSCVECPDLTAEPFCLVAPGLCGSPKVVEMGGVSNFMPLYNPDKMYDLKHFNRLLGVDPVVVLGTGAGPFIDGHNCCELLANALISK--GEVQSLNRIAKVTDENRGYTIQFLPKN--ETKFVLMANLFASNGKPGKVLKINCKNRIKDEDFPAAVRKCLAEKFKDKPLGLGGVFLVEGSKVRQHIPPKEFSEVPITSPEQLNNWLRFFDMNPPLVFVGTILTQDMGLEMILQHFHSFSDHGEGGHYHHDTDPHSVEYLAYFSLAEKAVHVDRPPCISNL--- +> +---IETLKPSNSELLPIVESALKSNFKNVTVEVGPCPDLSAEPFSMTSSGFGQKLVIADVGGPGNLFPKIHKEKEFDLK-ICKVCQSPFSFVFGPGAGPWKVVGRNCEMVADANLTTA-KVILSSGYVDPLNRRY--MLIFHYIIL--NASRSLLFS-------LCRLVHCKCSVRIGKDNFPETIRKALAKHYGERCVSLAGIFLLREGEAKLHIMP-DFPGCQFSSSEEVDKWLQFFTMKAPLVCASVFHSYDPGHKLRMEHTHCYSSHGDAGHYYYDTTPDTVAYEGWFTAAEKIYRIDE---------- +> +-TITPRNPPPLSELAPVIERALSQTFTHASASVIQCPDLRNPPFGLAAPGLSGNPRIADVGGQPNLFPSPNFDAKFDLLALAREMQMNPRFVLGAGAAPFQDIGHNAELVPNLAWDGRTVSSPDLSDVDSLDSEDEAIKCR--PSP--STNCALMVNLFGSSGDPGPVLKITARTRTGVENFTNTIRAGLLKAYGSRPVSLGGVFLLKSGRAKFHVMP-DFPPAPFKDRKLLQEWLRYRTCAAPVVCLTVFHSADPENGLRMEHTHCFDLEEKGGHYHYDIEGEEVEYEAYLNVAESVYRIDRP--------- +> +IEKKTLHVPPLEEIATALNRGLRSNFEQVEASVVECPDLTQQPFTLACKGLNGTPKLIDFGGLAYAFPVAQKDKVYDVKDFVKTVKTDPAFVIGAAGGPHPYTILNSDGVYNLEIKN--GNVRNLSQTLIVDEDG-KAVQGSLPDS--ETRCAALGNFLICNGKPGKVVKVHVKKRIGSDDFVTSIRKVLVDTFKGQLIGLGGTFLLKEGKINVHITP-DFSKTPIVTVADLNAWKRFFDLTAPLVAVGTVTTNDGGIGLSDRHFHSFSHHGEAGHYQHDITPDTVEYLGYFVPAEEAYRIDRPEVA------ +> +-KKVVLSPPPLSALASAISLELSSNFSESSCTVETPPDLTLPPYHLAGPGLTGSTRVVEVGDPSYLIKF-DFTRRYDLQPISRKTDMSPSLMIGAGAGPFYVLGQNTELMPNFAYGTSPEATRNRTHYAKITPAD-GVSCCQL-PD--SSKFGLMCNLFCSDGTPGPCLHIKAKSRTGRDNFTQTIQNAIGAAFNKQLVSIGGVFLIRSGKVNLHVMP-DFPASPFNNHDDVEKWLRYFEMEGPLVCLSVLHSGDDGLGLRMEHTHCFTDTTKGGHYHYDVDETEVEYEGWFNVAEHVYRVDPPP-------- +> +---------------------------------------------MTSNGFGRKLVIAEVGGPGNLFPKIRKEKEFDLQDVCKECHAPSSFVFGPGAGPWPVVGRNCEMVADANFASS----KVATKIASLVEGHTPYKMSI--ID--SPKFSLMANLAVSGEGPAEVVHCKCSVRVGKDNFPETIRKGLAKHYGKMCVSLGGIFLMREGEAKLHVMP-DFPGCPFKAREEVDKWLRFFTMKAPLVCASVFHSYDPGHNLRLEHTHCYSEHGDAGHYHYDTTPDTVVYEGWFTAAEKIYRIDE---------- +> +-QKVPLSPPTLREIAVALQFPLAANYSHSTVDVVQCPDLRKAPFYLATAGLSGAEKISDVGGQPNLFPTPRLDCKWNLLDIARAMEMAPHGLLGAGAGPFHIVGHNCELVPNIAWNDGFENATNSTYLAQIRQGE--PSVEKS--P--SLDCALMINLYGSLGHSGPVIKITARGRVGDKSITELMRKALANAYGDRMVSLGGVFAVKKGTSKYHIMP-DFPPEPFKNAKQLNDWLTYHEFEAPVVCLSVLHSADPGKGLRMEHTHCASMRDVGGHYHGDINGEEVEYEGYFNVAKTLYRIEKPEVTLE---- +> +-TRHLLSPPSLDELAQALHPALTANYEDASISVVDSPDLREAPYRLAARGLSGNECVADIGGQPHLFPRPRLEKKYSMLECAQCMEMSKDLLIGAGAGPFHVLGKNSELAPNLSWTDGFSKLENKTHFAMTGEHNTDVVCEPS--P--STDCALMMNLYGSSGNAGPVLKVTARARKGEKSFTECIRQALHQVYGERQITLGGVFVIKRGKALFHVMP-DFPPEPWKEREQLNSWLTFHEFGSPMVCLTIFHSADPKLGLRMEHTHAFSSKSEGGHYHFDLPVGEIEYEAYFNTAKVLYRLDQPEVR------ +> +-ARYELSPPSLEEVAKVLASALPRNYAESSVEVVDCPDLRKPPFYLATEGLGGRRTIADVGGQPNLFPRPRRDKNYSLIETAKLMKLDPDSLIGAGAAPNHVHGINSELAPNLSWQGFDHNVNNLSRSVRIVPGDVADSVGSIFSG--STECSLMVNVYGSLGLPGPVIKVTARGRRGTGSISEFMRTALRDVYGDRQVSLGGVFVLKSGRANFHVMP-DFPSGPFKDRKAVDSWLTFHHFAAPIVCLSTFHSADLHNGLRMEHTHCFSDKPVGGHYHYDLVGEEVEYEGYFNVADTLVRIDQPK-------- +> +VEEKPLFVPPVEDVVQALQDGLASYFGSVSVESVECPDLTAEPFCLVTQGLCGSPRVVEVGGVSNFMPLYNPDKIYDLKDFNQLLAVDPVVALGTGAGPFLDNHRCCELLANARISN--GEVQSLNRIAKVTNENRGYIVQFLPKN--ETKFVLMANLFVSNGKPGKVLKIHCKNRIRDEDFPAAVRKCLAEKFKGKELGLGGVFLVEGSKVCQHIPPEQFSKVPITSPEQLNNWLKFFNMNPPLVFVGTILTHDMGLEMILQHFHSFSSHGEGGHYHFDTDPHTVDYLAYFSLAEKAVHVDRPQCTSTLK-- +> +-SKHTLKPPPLEDIATKLQSALANNYRHSSVTATECPDLRHAPFHLATQGLSGNECIADVGGQANLFPTPRLECKYSLLDVAKAMEMDPESLVGAGAGPFHVVGQNCELAPNLSWKGSFDNVENRTYVAKIAKDSGEAMVSRC--S--STDCALMVNLFGSSGMPGPVLKITARGRKGKGSLPECIRTALHAAYGSQPVSLGGVFLVKSGKARYHIMP-DFPSAPFENRDDVEKWLTYHTFAAPTICLTVMHSADPGLGLRMEHTHCFASQNAGGHYHNDVESD----------------------------- +> +ITKLALSPPPLSDLATAIAAGLRTNFTTSTVSVSTPPDLRNAPFFLAGPGLSGNARVADIGGVQNLRPTPNLDAKYDLLGIARLMGMSDELLVGAGAGPFHHLGYNSELMPNIAYGASDGVINNCTHYAKITQDG-GVRCEKI-G--ESVGFALMANLFGCDGETGPILHVTARGRKARQSFTESIRAGIRAVYGDKLVSLGGVFVIHKGKTKLHVMP-DFSDKPLRSPDDLDGWLRYFDTDPPLVCLSVFHSGDDGDGLRMEHTHCFAGDCRGGHYHGDVDETDVEYEAWFNVGEVLYRIGQPD-------- +> +--ATPRKPPPLAGLAAIIQDALRQNFAHASAEVIECPDLREAPFELAAQGLSGNPVIADIGGQANLFPTPNLDAKFSLLALARDMRMSPELLIGAGAAPWQDIGHNAELAPNISWEGASISVTNKTRIVEVNPSANSSPEHSICRPSPSTNCALMANLFGSSGLPGPVLRITARSRTGAHNFTNAIRHGIHAAYGSHPVSLGGVFLLKSGSAKFHVMP-DFPSRPFRDRKQLEDWLKYQTCAAPVVCLSVFHSADPGLGLRMEHTHCYDLREKGGHYHYDLQDGDVEYEGYYNVAEVIYRIHRP--------- +> +---LRTFEASLEDIAAAFETGLKSCFQNVSVSVADCPDLTNKPFALPSSGLLGNNTVCDVGSFSYLIPVADTSRRYTFSEVISASKLQTGQLIGAGAGPFFTAGKNCEMAAIVKVAEN-DVRSNNTLHGVYNKSED--KPGVLKAT--DNNFALLGHFLATEGNPGKVLAVDVSVRAKDGSIYTFLREALTAKFGSAPVALGGAFVLDNSKGRFHVMP-DFPKEPVDSPAKISSWLKFYEMSPPVMGVGTIVSHDPKMDLKLEHFHCYSEGAEAGHFYYDTQPETAHYRVYLAPAKSILRIDRA--------- +> +-KKLFLSPPPLAELATSISAGLSTNFSSSSCTIETPPDLTLAPFHLAGPGLTGSPRVVEVGDRSYLVKR-DLTRKYDLRAVARQIDMNPSLMIGAGAGPFFVLGQNSELMPNFAYGTNAQSVRNRTHYAKLKPDG-SVQCSALS-P--TSSFGLMGNLFCSDGEVGPCLHIRAKSRTGALNFTETIQEALKTSFGDKLISIGGVFLITSGRVNVHVMP-DFPAQPFKDRAAMTTWLRYFDMGKPLVCLSVLHSGDDGGGLRVEHTHCFTETDKGGHYHYDVDDTTIEYHAWFNVAEYVYRIDYPAEHQR---- +> +--HRALSPPSLSSLAASISSGLSTNFAHWSCDVETPPDLTLPPYHLAAPGLSGSTRVADVGGPPYLESKLDLTRKYDLAAIAQDVNLPASFLLGAGAGPFFHLGHNSELMPNYAYGTSSPAIRNRTHYAKITPSNDPV-CCPL-PS--STGFGLMCNLYCSQGLPGPALHIKAKARTGPLNFTQSIQDGLKATFGENLISLGGVFILKSAKAKMHVMP-DFPKNPFQSRKELVEWLRFFDMTGPLICLSVLHSGDDGGDLRHEHTHCFTVTSKGGHYHFDLDETQVEYEGWFNVAEDLYRVDQPG-------- +> +---IETLKPSNRELRPIVETALKTNFKNVSVEVVSCPDLSIEPFSMTSTGFGRKLVIAEVGGIGNLFPIIHKEKEFDLQEICDSCQAASSFVFGPGAGPWKLVGKNCEMIADANFSIS----KVATKIVSISSSDPSYTLSIL--N--SPKFSLMANLALSEPGTG---ECTANVRFELIIFLKLYEEGLLNITEKSCVSLAGIFLLREGEAKVHVMP-GFPGCSFNTKEEINKWLRFFTMKAPLVCASVVHSYDAGYKLRMEHTHCYSSHGDGGHYHYDTTPDTVVYEGWFTAAEKIFRIDE---------- +> +----------------------------------------------TSNDFDRNLTIAEVGGPGNLFPTIHKEKEFDLKKICEECHAPSAFVFGPGAGPWQVVGKNCEMVADANFAI----PKVATKVAFINDGQ-STTYKQSTID--SSKFSLMANLAVSGEGPGEVVHCKCSVRVGKENFPEAIRKGLAEHYGSRCVSLGGIFLLREGEAKLHVMP-DFPGCPFKSTEEIDKWLRFFTMKAPLVCASVFHSYDPGHKLRMEHTHCYSEHGDAGHYHYDTTPETVVYEGWFAAAEKIYRIDE---------- +> +-DEFQLEKLELETIQNALNKNLPKFFEKVSVSVSDCPDLTQQPYNLATEGIGGKGSLIDIGGPPYLIPLVNREKVYDLAKIIEHVGKEDGYASGAGAGPWPSQGSNCEMVINLKLDKDGGVVSNKSKVALTSSGAEDLTVKELGNE--ESRCALLANLLVSGG-KGKIIEIKCTKRIDKSNFTAAIRQALKEEFGEKPVGLGGLFTVTLSDTKIHVMR-DFSNTPLESDDDVNNWLKFFHIKPPMLFQSVLVSSDPGLDLRIEHAHGWNLRSEAGHYHYDDMPDTVEYHGIYAVAQKIIRIDRPQETHQLGRD +> +-SKKILYQPPVTELISVLTDGLTANFEKVIVKLGRCP--RDPERQPNQYDLCGDPTILEIGGPAYLLPLAQKDKFYNIETLLRRIDYHGSFVIGAGAGLWPHTGSNCELIIHHHINTQIGSVVNNSRYAFVDKCTGECVVAQHHNEQHQATCPILANLYVCKGEPGMVIKVYAKKRTGKLDFIASMQKALGNYYKDELVGLGGMFTMRNGKIKQHVMP-DYSNTPLTTEAQLNDWLHFYEMKTPLTAVGTFVSAETELDLRVQHFHSFAHNKMAGHYHIDTTPDTIEYEGYFNIASVLYRVDQPTNKLQFGKD +> +VEKFPLSPPSLEELAKNLGAPLAANFKESSVRVVQCPDLREAPFRLATEGLSGDEKIADVGGQPNLFPRPRLDNIWSMAELSKSMEMSPESLLGAGAGPFNIIGQNSELAPNLSWRGGLENIDNRSQVIQIRRGTGAVSVGT--SP--SVDCGLMVNLYGSLGERGPVLKITAKGRTGPKSFTECIRKGLRAAYGERTISLGGAFLVKSGRATYHIMP-DFPPEPFKDRKQVDDWLTFHDFDSPIVGLTVFHSADPGNGLRIEHTHAFSPKNAGGHYHYEADGSEIEYEGFFQTAKVIYRVDRPSTA------ +> +-ETFPLSPPSLEEIAAHLQAPLAANYTHASVGVVRCPDLRAAPFHLATEGLSGDEKIADVGGQPNLFPRPRLDTIWSLPEVARAIGMSPEGLIGAGAGPFHVLGQNSELAPNLGWSGGENEIDNQSRVILIERGGKKNAVSVRAAP--STDCGLMANLFASRGEPGPVLRIAARGRKGPKSFTECIRQGLRAAYGERTVSLGGAFVVRAGRATYHVMP-DFPPEPFRDRRAVEDWLTFHDFDAPVVGLSVLHSADPGMALRMEHTHAFSAEDAGGHYHFEAEGEVIEYEGYFNTAKAIYRVDRPAG------- +> +VKKVALSPPPLHALAEAITSTLSSNFSSSSCTVETPPDLTLPPYHLAGPGLTGSPRVVEVGDPSYLVRS-DFSRRYELRAIASQADMSPTLMIGAGAGPFFVLGQNAELMPNFAYGTASTMTRNRTHYAKITSPSDAVSCCPLPS---SSNLGLMCNLFCCDGEPGPCLHVKARSRTGPLNLTQAIQQGLKSAFGDRLISLGGVFLIRKGKARLHVMP-DFPAQPFRDHDDVVKWLRFFDMAGPLVCLSVVHSGDDGLNLRMEHTHCFTETTKGGHYHYDVDDTEVEYEGWFNVAESVYRVDYP--------- +> +VKKVTLSPPPLHALAEAITPTLSSNFSSSSCTVETPPDLTLPPYHLAGPGLTGSPRVVEVGDPSYLVRS-DLGRRYELRAISRQTDMSPTLLIGAGAGPFFVLGQNTELMPNFAYGTDTMTTRNRTHYAKITPSD-AVACCAL-PD--SSNFGLMCNLFCCDGAAGPCLHVKARSRKGPLNFTQAIQQGLKSAFGGDLISLGGVFLIRSGKAKLHVMP-DFPAQPFRDHDDVVKWLRFFDMDGPLVCLSVVHSGDDGLNLRMEHTHCFTETAQGGHYHYDIDETEIEYEGWFNVAESVYRVDYP--------- +> +--KLSLKVPPLEELSSILDPALRKNFGQISIDIVDCPNLREAPFSMTGAGIGNGLRIAEVGGIPNLYPRGG-KKIFNLKKVCETCEMPHAFVFGPGAGPFEAVGHSSELVANANFIE--HEYKVANKVSWVVPSGKGYTMSTI--D--SSDFEITANLAISDGCPGKVLRIRAAKRNGEMNYPEAIQKALGAHYGDTLVSLAGLFVLQKGKVRMHVLP-DYPESPRKADEKKDDWLQYFEMDAPIVFASVVHSNDVGGKLRVEHTHGYSEHGDSGHYHIDTTPNTVEYEGYFSPANIVYRIDM---------- +> +-TKYELSPPPLDELAAVLQTGLQQHFESVSVHVTRSPELREAPFHLAAAGISGRERIGDVGGPQNLRPLPRLDHKYHLREIMDLMEMQDGLVIGAGAGPFHHVGGNTELMPNLSYTD--GVANNQTRFARIVPATLAHRCRPLPAP-KSADSALLTNLYASDGAPGDVLKMVAHGRKPDPDFTAAIQDVLRSTYS-QPVSLGGVFVLRRGRALLHVMS-DFKTEPRLPG-NQDNWLTFFDVAAPLTCLSVVHARDPGLRLHLEHTHCFSERGEGGHFHHDSTPADAEYEAYFNTAKVIYRIDGPG-------- +> +-TRLELSPPSLQEIAQVLAAALPRNYVASSATVVDCPDLRKPPFHLAAEGLCGGEVAADVGGHTHLVPRPRLDKNYSLPALAKLMQLSPDSLIGAGAGPNHVHGYNSELSPNLSWKDFEHVTRNLTHSTRVVGDRAGVACGLS--N--SADCSLMVNLFGSEGRPGPVIKVTARGRCGNASFTEFLQAALREAYGDRQVSLGGIFLLKAGRAHFHVMP-HFPTPPFEDQKTLDTWLTFHDFAGPIVCLSVLHSADPQKGIRLEHTHCFSNKPEGGHYHYDLGDEQVEYEGYFNVAHAFVRIDKPK-------- +> +--KLDLLSPELEELAPILNVEMENYFQEIDVDIVDCPDLTKPPFNMTSRGFGPDLRIAEVGGVGNLFPKIRRDKLYNLKSICDLCELPNGSVFGPGAGPRTSVGVNCEMVADANFGE----GTVNSKIGKIDGQS--FVQETTC----DPCFGLLANLGVSSGETDLVLKITARNRLTDYSFPHAIQQALFNHYRAKIVSMAGIFIQKTGDAKVHIMP-DFPERDFSCWEEEKSWLRYFKVRSPLICCSVLHSVNPGIDLRLEHTHCYSDHGDVGHYYTDIDPETAQFEGYFSPAKFLYRIDQIDS------- +> +-TTHPLSPPTLGEICSTLRPALKANYSDSSIEIVTCPDLTAPPFHLASQGLSGKESIADIGGQAHLFPRPLKEKKYSLVDCAKSMGMSQQLLIGAGAAPWHVIGQNAELAPNVSWEGEESRVRNQTFVTRVESHGGQVRCERL--P--SMEFALMMNLFGCEGVTGDVLRVTAKGRRGQGSFTECLRQALHAEYGERQVSLGGVFVMKKGKAVFHVMP-DFPPEPFPSHDAVNEWLTFRQFSAPIVCLSVLHSADPKLGLRMEHTHCFSDKDEGGHYHHDILPDE---------------------------- +> +----ARNPPPLSELGSIIARALQQNFAHASASVTQCPDLRKPPYGLAASGLSGNPRIADVGGQANLFPSPNFNAKYSLLSLARDMEMSAEFVLGAGAAPFQDIGHNAELAPNVAWQADCVDIVNETRIVEVVAGEDSVSCWRA--P--SANCALMVNLFGSSGLPGPVLKITARGRTGPANFTSSIRAGLLAAYGSHPISMGGVFLLKAGKARFHVMP-DFPAPPFKDRRVLQEWLKYHTSEAPVVCLTVFHSADPGLQLRMEHTHCFDLCRKGGHYHYDLETDEVEYEAYLNVAEVVYRIDRP--------- +> +-NRHELSPPSLTEIAQVLASALSENYASSWATVVECPDLRQAPFNLACEGLSGAEVIADIGGQANLFPQPRLEKNYSLIKCAEAMGMIPTSLIGAGAGPNHVHGVPSELAPNLCWKNGFENVNNMTRSARLIPQNEGSESAVACPYSGSTDYSLMMNLYGSHGLPGQVVKVTARGRRGDASFSEFLRSALRKAYGDHQISLGGTFIMKRGKAKFHVMP-PFPPQPFKSQEALDGWLSYQTFSGPMVCLSVFHSADPKRGVRLEHTHCFNGDSQGGHYHYDISSDQVEYEGYFNTAKTFVQIDKP--------- +> +ITKRPLHQPPLDELMSVLREGLAANFEEVSVELGTCPDCERKP---SRYDLCGNPIILGIGGPAYLLPLPQKDKLYNIEGILRRIDYRNAFVIGAGAGLWPRIGGNCEAVVHHHIDTRVGSVINNSRYAYVDKSTGECVVQQIGDNEQHQAIMLLADLYVSEGEPGTVVKVCAKTRTGKSDFITSMQKALANHYKDKLVGLGGMFTMRNGKIRQHVMQ-DYSDIPLTTEAKLNNWLRFYEMETPLTAVGIFVSAETDLDLRVQHFHSYAHNKEAGHYHIDTTPDTIEYEGYFNVAGTFYRVDQPPNRLQFGKD +> +--SAKLHVPSLDELVPLLNDALSKNFAEVEVKVLDCPDLTKAPWHLAGKGLCGSCRLLDIGGEFNLFYAKNHTALYNFDECARLAGVPKAFMIGPGAGSRPIIGKNCELMANVNIGEK----NFASYVAKITDDE---RPQQVNYP--ENQLGILCNLFACDGEPGKVIYFRAKKRTGERNVVSCMREGLRPVYTGQTVGLGGAFRIVKGKAHAHIMP-DFLERDMP-VEEVKSWLRFFEYEAPLTCLSVFLTEDIDLNLRLEHTHFFSDHNQGGHYHYDTTPDEVEYEGFFAPCEHVFRIGQP--------- +> +-------------------------FVEVSVTVVECPDLTNKPFMLASQGLCGKPRVMDIGGTAYLLPTPQMDKVYDLSQVPSWSELGSSLSIGAGAGPSAVVGKLVELIPNIFIDE-LGKVHNHTHISKVDDKTGQHVVEKLG---NCCDSNHLTNLFVSEGRPGKVLKVIAKHKKSEGNFICGMQSSLKQRYGTQPVGLGGVFVLTKGKARIHVMP-GYAEYPLTSISMINEWLKFYEMSSPLTAVGYLMSHDPGLNLRMEHFHCFSDHGDGGHFHHDVTPELAEYEGYFNVPEYMFRVDL---------- +> +--EFVLHKPSYHEVSAALESHLKDCFESVKCSITDCPDLSDTPFCLTLKGLCGKGTICDVGSFDYLLPVPKTDRHYDLLDVFKSAGITVGAVIGAGAGPFFLTGSNSEMVINISSEN-GKVSKNSSLLGSYDKENNKPLITKA--D--NTKFALLGQMYMCEGKSGPVIELCVSGRIRDGKLDAMIREALHKKYGSSSVGLGGVIIQEKGKSLYHVLP-EFSQEPIDSNEKLRNWIKMFEMESPVISVGIVVSHDPHHGLRLEHFHCFNDHTNCGHCHFDTHGPSVSYRAYFALAEHLVRIDQPK-------- +> +ITKVQLDPPTLTALLPAIRAGFSSNFKNSIIEITQSPDLRQPPYYLATPGLSGHPRIADVGGQLFLAPGPDFSKKYDLLSVARQMEMSTEQLIGAAAGPFYSLQINTELAPNIHWKLATDVLYNETHYTKIIASEPGYRCSKIDHE--TTGFGLMGNLYGSDGLPGDLLHIVAKSRSGPLNFAATIQDALAKYFGDKLISLGGVFVVTHGKIKVHVMP-DFPERKFERRADVGPWLRYFNLEAPLVCLSVLHSGNDGLSLRMEHTHCFSNAVSGGHYHYDLDDTEVEYEGWFNIATVLYRIDQPP-------- +> +-SNHSVHEVQKEELVEVLREGLKDCFQSVKVNVVPCPDLTALPFGLLRPGLAGQSVACDVGSMAYLLPVADTSKRYSFDQVVDLSKVSGGHLFGAGGGPFFTHGKSCEMAASLEFAN-GKICSNSTLHGVYDEQTGAPQVIK--AT--DNNFGLVGQLLSTEGLPGSVIEVDVTGRLKEGSVYVFLREALTAAYGDKPVVLGGVFVLTDSKARFHVQP-NFPPYPVDTPARMAEFIKAFEMDPPVLGMGTLVSHDPGIDLKLEHFHCYNAKNLAGHFYWDTEPEKAHYRLYLTVAKSLLRIDPKKK------- +> +--NHNAYDVQEEELAEVLREGLKDCFRSVKVNVVPCPDLTASPFGLLRPGLAGKSVVCDVGSMTYLLPVANTSKRYSFGQVIESSGVCGGQLLGAGGGPFFTHGKSCEMAASLQFAN-GKIASNSTLHGVYDEQTGTP--QVINAT--DNNFGLVGQLLSSEGLPGSVVEVDVAGRLKEGSVYVFLREVLTAAYGDKPVALGGVFVLTDSKARFHVLQPNFPPYPVDTPARRAEFIKIFEMDPPVLGMGTLVSHDPGIDLKLEHFHCYNAKTLAGHFYWDTDPEKAHYRLYLTVAKSLLRIDPKEK------- +> +---------------------------------------------MTSNGFGRKLVIAEVGGPGNLFPTLHKEKEFDLHQICKDCNAPSSFVFGPGAGPWQVVGKNCEMVADANFASS----KIATKVASIEEGQKPYKVDVI--N--SPKFSLMANLAVSGEGPAEVVHVKCSVRSGQDNFPETIRKGLAKHYGEKCVSLCGIFLLREGEAKLHVMP-DFPGCPFKAEEGVNKWLRFFTMKAPLVCASVFHSYDPGHKFRMEHTHCYSDHGDGGHYHYDTTPDTVVYEGCME-------------------- +> +--RHKLDPPPLDELANALSDGLARFFADVLVEVVDCPDLTAAPFGCAFSALGGDPCIIDVGGVDNLFPCARRGKYFDLSAIEQQIGAGRSCFIGAGAGPFQEVQHNCEWICNVRLPE-----ANESRCAVMEGTDSGYTIERP--K--TTCFGILGNLYACKGEPCKVLHIKAGRRTGKKDLPQCLASILASSFPSRPVSLGGVMAMHAGKARLHIMS-DFTDDPIRSNDAIENWLNYFEVPAPMTFMFVSTSIDPGMDLRTVHTHGWHEGKYGGHYHNDTTPDEVSYEVYVNVAECIYRIDRVSQTPDFNR- +> +---------------------------------------------------------MEVGGPPYLLPLVDRTKLYDIKTLSQRA-LGNKFAIGAGAGPFPLRGTNCEGIYNLKISA-DGKVTNKSYSAKVHGPEENCVLEQIPDT--ETKFGLLLNLFLSEGKSGKVLKVHCKKRTGPLNFIESIRYALLDFYKEKCVGLGGMFMIKSGKAHQHVMR-DFSKTPIYSEEELNQWLKFYEMPAQLNGVGTLITHENDLDLRLQHFHSFSSSNWGGHYHYDTTPDTVEYEGYFNVGEKVIRVDKPVNTHKFGRD +> +--VIENYVPSLNELKEVFKSALTSNFETVEVDIVDCPDLSKSPFNQTSSGFGCNLRIAEVGGPGNLYPGFHIDHQFDISTIGKVCEHPEASVFGPGAGPWPVVGQNCEMVADVNLKT----GKVGTRIAECDVKTKDLRSKSI--D--------VQNSYISKYQPG-------KERK-------TLQTVLEKDYRSEVVSLAGQFIIHTGQAKLHVMP-HFPGCPFKNNEEVDKWLNYFIMNAPLVCTTVMHSYDPGHNLRLEHTHCYSDHGDAGHYHYDVTPETVSYEGWFAPASKIYRIDEVA-------- +> +-TRHALSPPLLHEVAAVLATALPRNYRCSSATVVECPDLRTAPFGLAAAGLSGRPTVADVGGQGNLFPTPRRDKNYGLVDVAARMQLDEQALLGAGAGPNRVHGINSELAASLSWQGEAKNITDCSRSIRIAADNGHDHVQCVLS--GSTECALMANLYGSLGLPGPVLRVTARGRHGNASFPEFLRATLHDAYGDRQVSLGGVFLFKTGRARFHVMP-DFPPAPFADRQAVERWLTFHDFAAPIVCLSVFHSADPQLGLRIEHTHGFADRPAGGHYHYDHLAREVEYEAYFNVADALVQIDPARA------- +> +-KTYDLDQLPLDELSSTLQDHLSKFYGHVEVSVVDCPDLSKEPFNLAGSGLGGKTALADIGGVPYLMPVPYPAPIYSFVNLGKRMGFQDAHLMGAACVPFQITGSIAEFMPNISYSEGKTLVNHGSYYSEMVDD-KKYIMRPLA----SDCTNTLANVFISENKPSKVIKIVASKRVDKESLTVAIRDILRIAYPEKAISMGGMFLVRKGKIYIHVMPNDFSKTPCDTEEKANEWLNFFEASAPIVGLVTLHSKDPGFNLRDEHTHCIG-KGEGGHYHHDTTPDTIEYEAYLNIAQQIVRVDQPVVGNE---- +> +--RFKLNTPPLRCIIEAILPELLDNFENASVEVVQCPDLTQPPFNLTSEGLCGDENVFDIGDVTNLLPSLKREKLYNVKDLKQITGSDPLFIIGACAGPYPFFGADSECVENVKMTG--DRVENGTHVHMTKSDDPECFHKSLPDD--EMRFSMMANFFTSNGFKGEVLKIVCEVRKGPLSYSTCIKEALVKHFGNEIIALGGVILIENGKVKVHVIKPSLTKIPIKSEKELGNLLHFIELSPPLVGVGCIVSHDPGLNLRLQHFHLYTDHNQGGHYYNDTEPETIKYTGYFGVSKQFTKID----------- +> +--IYPMMPPNILEIADVLQNGMQPLFHDVRVDIASCPDLTTAPYNLAGVGLGGNTSLVEFLRHDVHTPWKH--RTRDILKVFTGS-IRDSFIIGSTFATKPTMPYYGHLIMNAMYTA-PMGIRNESRLIFAELRNGQTRIEKLTDP--NQMIYCKGNFFISEGREGPVIRVRAKGRKKSTDIITSMQTVLYEHYGWKTVALGGVLKMTNGRVACNLMW-DEYQEPILSFPDFVRAQQCICLESDMVAVGTIFNRQPLLEQRRSEFHCFNNYGAGGQFISDTTPDTTEYEGYFNVAENI--------------- +> +--VKELHMPPMEEVVETLQTALKANYKEVEVAIVDCPDLSSPPWDLAAKGICGDNCILDVGGVKNMYPINHPLKQWDIEELAKRVGMPGGFFIGAGAASPKIIGDNGELAPNTNIGTK----QIKTRSAEVAEDG--SCVQRM-YP--SNDVSAMANLFGSKGCAGKVIKVHVKVRTGKKSLITCMRQGLIKKYGDNPVALGGVFQLLQGKLKAHVMP-CFPQQDLVSQEIVDDWLNWYEVPAPATCLSVQVTQNMGLELRVEHTHFFTSNNHAGHYHYDTTPDECEYLGYFGIAEKLYRVDK---------- +> +--NYDVHEVRKEAVVEVFRNRLKEYFKSTKVNVVPCPDLTSPPFGLLRPGLAGQSVVCDVGSMSYLLPVADTSKKYSFDQVVESSGVHSGHLLGAGGGPFFTHGKTCEMAASLQYEN-DKIISNSTLHGVYGEQTGTPQVIK--AT--DNNFGLVGQLLSTEGLPGSVVEVDVADRLKEGSVHVFLREALTDAYGDKPVALGGVFVLTDSRARFHVLQPNFPPHPVDTPARMAEFIKVFEMDPPVLGMGTLISHDPGIDLKLEHFHCYNAKNLAGHFYWDTEPEKAHYRLYLTVAKGLLRIDPKKKTQSV--- +> +--RIKLNTPPLRCIVEAILPKLLENFENVSAEVVQCPDLTKSPFNLTSEGLCGDENVFDISDVTNLIPSIKREKLYNVKDLKQITGSDPLVIIGACAGPYPFFGADSECVENVKITG--DHVENGTHAFMTKSVDAECFHKSLPDN--EMRFSMMANFFTSNGIKGEVLKIVCEIRKGPLNFSTCIREALVKHFGDEIIALGGVILIENGKVKVHVVKPSLLKIPIKSEKELSNWVHFFELSPPSVGVGCIVSHDPGLNLRLQHFHMYTDRGQGGHYHNDTEPETIKYTGYFGVSKQFTKID----------- +> +-EEFVLPSVDIEDICKALNENLKAYFQNVDVNVVDCPNLAEPPYNLATNGIGGYCVIADIGGVPYLIPLVQRDKVYDLRTLIPECVGADKYISGAGAGPFKSQGSNCELIVNMYLSP-DDKVVNRSKVALTSSQNTDLTVKTLSDT--ETDSSLLVNVLVSSG-AGKVLDIKVSHKLDPTNFTTILRDCLNKKFTSTPVGLGGLFTVDRAPTKIHVMR-DFSTKPLLTDNDVEEWLKFFRVEPPFMSQSILVSTDPGLDLRVEHSHGWTTPAQAGHYHYDTAPQDVQYHGIYAVASKIVRIDRPKETHNIGRD +> +-TTHPRDPPPLGELAAIIQRSLLANFASASVSVVECPDLRQPPFYLASSGLSGNPCIADVGGQANLFPRPNFDAKFNLRSLAKDMQMTEGFLIGAGAAPFHDTGYNAELAVNLYTPPGP---HVGTGDPDVDQVRNGSRIIQVNQ----------------DGDTGPVLKITARARTGDKNFTNCIRLGLADHYGSRPISLGGVFLLKAGKAKFHIMP-DFPQEPFQDREQLKNWLTYHDFEAPVICLSVMHSSDPGLGLRMEHTHCFEANRKGGHYHYDLQEGEVEYEAYLNVASTVYRIDRP--------- +> +--SAKLHVPSLDELVPLLKDALSKNFAEVEVKIADCPDLTQEPWKLAGKGLGGNGRLLDIGGEFNLFYEKNHGSLFNFDECAKLAGVPKAFMIGPGAGSRAIIGKNCELMANVNVGEK----KFDSYVAQLTSDER-PLQ--VNYP--ENQLGILCNLFASEGEPGKVIYFRAKKRTGEKNVVSCMREGLRPVYTGQTVGLGGTFRITKGKAHAHIMP-DFLERDMP-VEEVKSWLRFFEYDAPLTCLSVFLTEDIDLNLRLEHTHFFSDHGQGGHYHYDTTPDEVEYEGFF--------------------- +> +--KRTLYTPSLTEVASVLEKALKKNFKEASVTVCQCPDLTKMPFKLAGAGLNGNTAVADVGGVINMEFLSNNKYHYDVKELSKEV--GLPFWIGAAATKPALAKDNSELMPNLNVAS----GVNNSKEAYVGTDGN-GHLVDY--P--HSEFSSLGNFFVSEGKPGQVLKIIARNRTGKLNMVTCMRQGLAEHYGDKQVGLGGVLLINKGKIRSHIMP-SFPPCDVYGK-QGIEWLKFYEVTAPFTCLSVLVTHDKYKDLRLEHTHFFSHGKDGGHYHYDTTPEQVEYEGYYNIATDLYRVGRPA-------- +> +--HIKLNTPPLSCIVKAILPELLKNYENASAEVVQCPDLTQPPFNLVSEGLSGNENVFDIGEITNMIPSIKREKLYNIKDLKQITGSDPLVIFGACAGPYPFLGIDSECVVNVKMTG--DQVENGTHAHMTKSNDPECCHKMLPND--EMRFSFLANFFTSNGFKGEVLKIVCEVRKGPLSFSMCIREALVKHFGDEIIAIGGVIFIENGKVKVHVIKPSFMKKPSKSEKELENLVHFIELSPPLAGVGCIVSHNPGLNLRCQHFHLYSDHNQGGHYHNDTEPNTIKYTGYFGVSKQFTKID----------- +> +--------------------------------------------NIAAEGLGGRPRLLDVGGVPNLVPLVKREKLYDMSEFPQMCDMKGGLIIGAGAAPYTFLDRNAEMMINVAFSKSGEVQNQKTTIARTFDADNSQTLIHLPKE--ETKISLLGNLFLSEGKPGKVLRITAKKRTDSDNFVSCIRKTLVKGYPGQPVGLGGVFTVANGEVKTHVMP-DFSKVPLETDEDVANWLKFYNTKAPFTALSFLLSEDPGLDIRLEHSHGFNEAVEGGHYHTDTTPDTVEYLAYYNVAEYIYRIDQPKETHQVGRD +> +-HNVPLHVPTDEQLCEVLSAALRSNFAEVEVNSAKCPDLTQPPWCLAVSGLGGDCRIADIGGTLNLEAPITRTLHYNLADVLQAIGKPSAHVMGPGAGYAGVAGINCELMATAQVVGTDGTDPKQDQCVETDPSS-TYLLEPY----SSLEVGPLMNLLISDGDPSSVIHVRVRGRIGESNLVSCMREALDAGFG-EVVGLAGVFQVLDGKVHAHVMP-GFPACYLRTDAQVQQWLHFFEMSAPLTCLSVMVSRQIELDLRVEHTHFYSDHGCGGHYHYDTTPETVVYEGYFVAAKTLHRVAQA--------- +> +-REVLLEKPELAEVATVLQNGLKAHYADVTVEVVDCPDLTQSPYGLTASGLGGRPCIIDVGGIDNLFPRVNADKEYCLKEIAERTGRKDFHLVGAGSCGYSLIKCNSELVVNAGHDH------IKSLCARMVDNHKKICCEPY--K--SYRCSALANVFCSKGETGKVLKFHAKKRIGKPDFIACVQQVLKDKYGERPVSLGGSFQMLSGKAKVHVMS-DFTRNPIRTQEFINEWLKFVEAQAPMTFMTVCTSVSPGLEMRLTHTHGHSSPILAGHYHYDLSPDEIEYEGFFGVAESIVRVDQVNQTPNWH-- +> +--VLDLAPPSLDELKAVIENGLHDYFVESSVTITDCPDFKTEPYNLEGSGLSPDLRIVDCGGHGNFFPKFQRHKQFDLKKISKTSELPQGWIFGPGAAPRETVGVNAELVANANFNTN----KVNCYNGRLTPDGKGYLEGTH--S--DTCFKMIANLALCSDEAGRVLRISAKKRTGDGSFTEIIQKILASHYRNKLVCLAGIWRFEKGRGYFHIVP-DYPEKDFEKLDDIKNWLHFFELPAPMTMTTVIHSNDIGLDVPVEHTHGFSGRGHCGHYHGDVTPSEAVYDGYFLPATKLYRIDNTKH------- +> +--VINTLKPSNNELRSVIETALWKNFKNVQVAVSNSPDLSKPPFRMTSNGFGKKLTIAEVGGMGNLFPVLR-KEEYDIREICSLCDKKSAFVFGPGACPKSVMGTTGELVADVNLSTGMAARAVASKVTTIVNDE-CLPYKTTAID--STKFSLMANLAISEEGPAEVVRATFLVAP----------PTVSRAHTCSCVSLAGIFLLLRGQASAHIVP-DFPTGNFKSIEEEEQWLRKFTLKAPLVCTSVFHSYDAGHRLRMVHTHCYSDHNDAGHFYTDITPESAVYEGWFTAAEQVYRIDK---------- +> +-KTCDLEPISLKELSTTLQDHLSKIYGHVKVSVVNCPDLSKEPFNLAGSYLGGKTAIADLGGIPYLVPVGYAAPIYPLIHLAKKMGFQDAHLMGAACVPFQITGSIADFMPNISYSTGKTTVNHGSYYSEMVDDK-KHIMRHLA----SDCVTVLANVFISENKPSKEIKIVASKRVDKESLTIAIRDILRIAYPEKAISMGGMFLARKGKINIHVMPNDFSKTPCDTEEKVNEWLKYFEASAPIVGLVTLHSKDPGFNFRDEHTHCIG-KGEGGHYHHDTTPDTIEYEAYLNIAQKIVRIDQPALNNE---- +> +--IHPITPPNLSEIADVLQNGMQPLFHDVRVDIASCPDLTTAPYNLAGVGLGGNTSLVEFLRREVYTPWQH--ITRDIRKVFTGS-IHDFFIIGSTFATKPTMPYYGHLIMNAMYTA-PMGIRNESRLIFKESRNGQTRIEKLTDP-NQMMYTYKGNFFISEGREGPVIRVRAKGRKKSTDIITSMQTVLYENYRNKLVALGGVLKMTNGRVGCNLIW-DEYRDRILPFPDFVKAQQCICLESDMVAVGTIINHQPQFEQRRSEFHCFNNYGAGGQFITDTTPDTTEYEGYFNVAENI--------------- +> +---RSLYIPSLEELSSVLQTGLRKNFKEASVSVCYCPDLTQPPFSLAAPGLGGNASIADVGGQLNMHKVNNNKYHFDIKVLSKEM-KGLPFYIGAGATKLSFRRDNSELIPNVDIKSN----INHSKEAYVAADGKGHLVEY---Q--STEFSSLGNFYACEGKRSTVLKIEARDRTGDLNIVTCMRQALFNHYGDKQIGLGGVLLVKNGKIRSHIMP-GFPPCDLPGTN--IEWLNYYEVSAPLTCLSVFVSADTHDNLRIEHTHFFSNHDDGGHYHYDTTPQQIHYEGYYNVAS----------------- +> +------------------------------------------------------------------------KEIFDLSKVPEWTELPDAFMLGAGAGPRHVEGINCEMMTNLQVTP--DGVNNQSYIAKVGTEDNKYIVKKVD-N--TTDCCLLMNLFVCEGKPSKVLEVKASKRTGPQNYMLCLRDVLAKHYGTQPVGLGGTFLMRKGSAKIHIMP-DYSDIPLESDAAVDAWLKFYEMKAPMIFMGYVISHDPDMDLRVEHFHGFSQHGDGGHYHYDTTPDEVEYVGYFNLGESMYRVDRPSVTHGIGRD +> +-EKASLYVPELSQLADMLKESLRGNFETVETKVVQCPDLTK--WGLAAPGICGNPRIIDIGGVPNLLPKHHDTAFFTIPQVAEDVGLKGAYVYGAGAASSKVVGVNAELMPTEHVSEN----CRCSRYSKVLEDG-SHTMEKY--N--SSEFGLLANLIACDGKQGNVVEVRAKKRIGKDNFVTCMRTGLAKRFGTRQIGIGGVFKVKSGKVRGHVMP-DFKPTVMIDGPEVEDWLQFYEMGPDLTCLSVFLTGDPGLDLRLEHTHFFSQTNEGGHYHFDTTPDEVEYVGYFLPAPDVYRVANAFK------- +> +--VQSLNVPSLTEVKEVLSRSLPAFFEEVEVEVTPCPDLRESPYLSSFQGLSDGNVILDVGGVDNLLPRPNKKKLYDLSDLVRQAVEKPTCLVGAGAGPCHVYGMNSELICNTCITG-----SSTSKVALMIPQEETGKEKHEVKDDVSNKSSVLLNVMLTEGKPGEVLRIRLRGRAGKKDVPQCIADCLKAHYGSRPVSLGGLLVLKKGRARLHCMP-DFSKEPIRTPEGVDEWLRWMEGEAPMRFMFVATSADPGMDLRLVHTHGWGERRYGGHYHNDTTPEAVEYEMVCMTAGAIARLDRVTQTPNWKRD +> +-ESYALSPPTLDELREVLAEGLNSNYEDVDVSVVSCPNLRQAPFGLVSEGLCGGTCVIDVGGVDNLFPKVNLTKEYCLREVAQQIGISEPHFLGAGSCGYSCTGRSAHRLPDSHGCSNAGLNENRSKCIVMDDDHVACCVRDY--N--EHRVSALANVFCSAGEAGQVLRVHVKHRKGEADFVGCIQRALRVKFGDRPVSVGGSFVMHKGTAKIHVMS-DFTQEPIMSQEFIKTWLKFFEGRAPMTFMFVCTSVDPNLSMRLTHTHGHNSNNMGGHYHYDLTR-EVEYECYLNVAEVVHRVDKQHQSPTWDK- +> +-KTCDLEPISLKELSSTLQDHLSKIYGHVKVSVVNCPDLSKEPFNLAGSYLGGKTAIADLGGIPYLVPVGYAAPIYPLIHLAKKMGFQNAHLMGGACAPFQIIGLVADFMPNISYSTDTKTGKTKVVHGSQYPEDKKYVMRHLA----SDCVTVLANVFISENKPSKVIKIVASKRVDKESLTIAIRDILRIAYPEKAISMGGMFLARKGKINIHVMPNDFSKTPCDTEEKVNEWLKYFEASAPIVGLVTLHSKDPGYDFRDEHTHFIG-KGEGGHYCNDVTPDIIEYEAYLNIAQQIVRVDQPALNNE---- +> +--VRQLYVPDFKEVAGVLKNGLGKNFKNVQVEVVKCPDLSKPPYSLASPSLSVGA-VIDIGGVINMEFLQNNNKHYDMKQIVKDV--NLPFFIGAAASAASKANDNSELMPNANVKT----GVNKTKEAYVDKTG-NCCLEDY--K--STEFSSLGNLFACEGNAQDVLKIKVSVRTGELNFVTCMRQAINEYYKDKQIGFGGVFTINKGKFKSHVMP-GFPPCDVFGKD--IAWLKFYTVDAPVTCLSVVLSNDKHNGARLEHTHFVSTRNDGGHYHYDVTPETIEYEGYFTLANQFYRIAKA--------- +> +-ETTPLATPILSEIAEALQNGMQPLFHDVKVDIASCPYLTAAPYNLAGVGLGGNTSIVEILPHGGNVSWYR--NKRDIQEILTTS-CHDSFAIGSSYATKPGMPYYGHLIVNATYRA-PMDLRNESRLVFAERPNGQTTIEKLTDP-NQMKATHKCTLFVSEGMAGRVIRVRAKGRKTRTDIITSMQTVLYERYRNKVVGLGGVLKMKYGSVACNLMW-DDYQEPMLPFDDFIRGQQCIYLESDMIAVGAIMNDKPELEQRRSEFHCFSNYGAGGQFINDTTPDMTEYEGYFNVAEK---------------- +> +-ESAELYVPELKELAQMLETSLKGNFKTVEASVVDCPDLTK--WGVAAPGLGGNVRILDVGGVPNVNDPAYHDICFDIPTLADQSELKDAYVFGASAAYHGVVGKNAELMPTEHLDTS----CRCTRYAKVTDDG-GHTCELY--N--SDKIGLLANLMACEGKPGKVIKVHVKERVGEENFVTCMRKGLASELGKKFSGLGGVFKVKEGMVKGHVMP-GFKNTVMVDGPEVEEWLNFYDMGPDLTCLSVFLSGDPGLDLRLEHTHYFSQKKEGGHYHFDVTPKEIEYVGYFTPSPIIYRIANAFER------ +> +-ESKPLFTPPLESLKEVLEKGLKSNFDEVDVNVVTSPDLMQEPFNLASEGLCGNPKVLDIGGVPYLVPLAQKNKIYDMKDYPKLTDFGATLIIGAGAAPWTYLERNAEMMPNLLVKS-DGSVVQKTHIARTHDKDDSYELLALPES--ETKMSLLGNLFLSNGQPGKVIEVKCKKREGEENFVSCMRKCVEKEFPDKSIGFGGVFCVQKGQVKIHVMP-EYSTKPLNSDADVENWLNFYQMDAAFTCFSVFV------------------------------------------------------------- +> +---RELYVPELTEIAEVFRKALSANFKEVSVSVEPYPNLCEPPYSLASPGFGGKTGIVDIGGVLNMEFLINNNKHFDLHEISNKT--NLPFFIGAGATKVSVIKNNSEWIPNANVKT----GVSLSKEAYVDNHG-NC--CQVDHP--STEFSSLCNLFGSEGTSGKVLHVVAHVRTGKLNFPACIRQALATHYPTQQVGVGGVFILKKGTFKSHVMP-GFPPCDVFETD--IPWLKFFEVKAPVTCLSVLLNIDKHGNARLEHTHFFSTADSGGHYHYDLTPEIVEYEGYFAPAQKFYRIARAQKPQQ---- +> +---------------------------------------------LPRPGLSGNPRVADIGGQNNLFPSPNLDKRYDLLSISELMDMKGGVLIGAGAGPFFDLGLNIELMPNIAFGASDRELRNCTRYAKVLDDD-SALCEGI-GT--STGCALMCNLLGCDGETGSLLHIKVKGRRGKLNFTEAIQKGLADVYGDRLISLGGVFVARSGKLKMHVMP-DFPGKPFKNRGEVEQWLRFFDMDAPMVCLTVLHSGDDKAGLRKEHTHCFGANRRGGHYHFDLDETTVEYEGWLNVAEILYKID----------- +> +----KLYVPELKELATMLEGALKENFDEVETKVVDCPDLTK--WGLAAPGIGGDPRIIDIGGVPNLLDPTYHGETFHIPNIALDVGLKGAYIYGAGAASSKVVGVNAELMPTEHVSKN----CRCSRYSKVEKDG-SHIMEKY--D--SSDIGLLANLVACKGEKGPVVMVRVKKRTGKENFVTCMRVGLEKALKNRQIGIGGVFKVVEGKVRGHVMP-DFKPTVMVDGPEVEEWLQFYEMGPDLTCMSVFLTGDPGLDLRLEHTHFFSQKPEGGHYHFDTTAENVEYVGYFIPVPTVYRVKNAF-------- +> +-KTTDLFVPELKELAGMLKTALEKNFETVETAVVKCPDLKK--WGLAASGICGDPRIADVGGIPNIMDYEHHKEVFHIPTIASQCDLPGAYVFGAGAASSKVVGQNAELMPTEHVKA----CCRKSKYAKVLEDG-SSTMEDY--H--SSDFGLMANLVACKGEQGDVVMVRAKVRKGKENFVTCMRRGLLNILEQYHIGIGGVFKVLKGKINAHVMP-DFKKEKIGEPGWTDDRNIHYEMGPDLTCMSIFVTGDPGLDLRLEHTHFFSQKKEGGHYHFDTTPKEVEYLAYFIPVPKLYRIDNPYPR------ +> +-------------------------------------------------------------------PAAWRERTYNFNHVAKQTDVPGAHVLGACAGSKHYVQVNSECIPNIRTEDDKEQFRNETHIAKIDPSDGSCVLMHYQNELQAAEFTLLGNLFLSEGKQGKVLKVSVKTRTGSGSLTTCMRKTLEANFE-TPVGLGGPFVQLAGKVRYHIMP-DFSSCLLNSDADVENWLTFHEFGAPFVNMATLISKDPGLDLRVEHTHGYSKNKTGGHYHYDTTPQEIEYLGYFSPAEFIYRIDGPTETHMIGRD +> +---KALEVLPLEEIAKVLENGLKKNFSDVNVSVVECPDLREEPWGLAAEGLGGATRVLDIGGVPYLMPSVKREKLYDMKDYPELTGLKSGLVIGAGAAPWPFLGRNAEMMPNIMVNE-DKSVIQETHIARTFDEDGSYTTQKLPAT--ETRNSCLGNLFISEGTPGKVLKIHCKKRTGAKNFVTCMREALVEEFPDKSVGLGGVFNIVAGKAKIHVMP-DFSPCPLNTDEEVNKWLK---------------------------------------------------------------------------- +> +---------------------------------------------------------------------------------------------------------------------EHNPPVNGSYFARVNPEDGRCRLEKYSEKHHDFGCALLANLFASEGQPGKVIEVKAKRRTGQLNFVTCMRQTLEEHYGNKPIGMGGTFIVQKGNVKAHIMPAEFSPCPLTSDEQVNKWLNFYEMKAPLVCLLVFVSRDPGFDLRLEHTHFFSRHGEGGHYHYDTTPDTVEYLGYFTPAHFLYRIDQPKETHSFGRD +> +VEKLELSSTTLADLASVISSGLRNSFSRSSCTVTITADLRLPPYHLAAPGLSGSPRVVDIGSPPSPPTQPHQKIRPPLH---RQTDRPPAAAHRRRRGPFHTVGKNCELAPNIAYSDGGRKVVNRTHYTKLEPGSGSLVPQCLQIEEESTGFALMANLYGSQGLPGEALHITATARTGSASFTDAIQDAIREHYGHPLISLGGVFVLKRGKANFHVMP-DFPGPELDSDEAIAKWLRYFDFEAPVVALSVLHTCGEELGLRVEHSHCFSETGRGGHYHYDVDETVVEYEGWFNVAEWVYRVDRPG-------- +> +--------------------------------------------------------------------------------------------MGAGAGPWPHLGTNSEMMTNLAING---EQHNKSRLATVVDDKPLRQLHTLPQD--ETNCALLSNFLISRGHMGPVLRVKCSKRIGPDNFVSCMRKAIHRRYPDQSIGLGGTFIIAEGRAKLHIMP-DFSSCPLLSDDDVNNWLHFYEAKAPLIGLSVFISHDPGLDLRVEHSHCFSLHGDGGHYHEDVTPDTIEYVGYFTPALKMHRIDRPTQTHNIGRD +> +------------------------------------------------------------------------------------------LVIGAGAGPWPHISRNAEMMPNLYVGA-DLSVRQETRITRTHDEDGSYSTHKLPAS--ETRNALLGNLFISDGEPGEVLRIDCRGRTGDKNLVTCMRETLEAASPELALGLGGVFSIRQGQAKFHVMP-DFSPCPINTNEEVNQWLKFYTVSAPLTVLSVFVSRDPGLDLRVEHSHGWGDGAQGGHYHYDTTPDTVHYTGYYNLAQTCYRIDRPVETHQVGRD +> +---------------------------------------------MTASSMGSSLRIAEVGGVSNLFPTPQKNKYYNLKELAETCELSDGFIFGPGGGPRHIIGTNCEMVADACFEKG--KEKVAVKMGVVTTKV-PQGHEMITT--EKPEFCLMANLGVCKGIPTSVLKIKARKRLGDLNFPEAVRRAIATHYKDQLVSCAGIFLLKGSKARIHVMP-DFPSGSFASAEEMEKWLKIFEIDGPIVAASVIHSKSVDNKLRLEHTHCYNKH-EAGHYYCDTDPESVEYEGYFAVASAVYRID----------- +> +---TRFLSPPLNELAAVLQKGLENNFDEVSVKVVDCPDLRSKPFLLAERGLCGSPRAMDIGGVPYLIPTPHMEKIYDLSQVPSIAELSDTLMVGAGAGPSHAVGKLSEMIVNMNADE-LGHICNHSRICKIDDESGKYVLHRL---ENSCDGCHLTNLFISEGKPGKVLEVRAHRRRSDDDLVGAMQKSVGSHYGSQPVCIGGVFVLTKGKARIHIMP-GYSDVPLTSNEMVDEWLNFYDMSAPLSAVGYFVSHDPVSKLR---------------------------------------------------- +> +------LEPEMEKLAEYLQVEFNKFYNEATVKVVNCPDLRKAPFHLVAPGLCGNTALLEVGSLSNLFPFPRMEKKYDFISFLETSGRSNDFIIGASLYPSS-NGHMGELIMNASFSEEGMRVKNRSYVAFLAQDHENVKLDIL-NDYNRVKCFLHGNFFISEGKPGRVLEIHAKARREDKELTKVIQHTLQKYYESTLVGLGGTFVVHNGLVRHHLMP-DIGQINCSDESRIRNWVKTRILTTPLVAVGTIVNKSSDLQLTTNHFHSFSEPLVGGHYYTNVEYGSAEYLGYFCPAKKLYRLDNDEICH----- +> +--KINLVVPSLDELKSVLHDSMVKNYESVSIDIVECPNLRESPFRMTGSGIGNNLRIAEVGGIPNLYPHGT-KKIFNLKKVCETCELPEAFVFGPGAGPFDAIGHSSELVADANLIK--SQFKIANKVSWIVSSANGYTMSTT--D--STDFEITANLAISDGCAN--RKICATKRIGELGYAESIQRAIESYYGHQLVSLAGLFLLHKGDVYMHILP-DYPVSPRKQDEKF-----FRESERKTTGXSVVHSHDNDGKLRVEHTHGYNENKSGGHYHIDTTPEIAQYEGYFAPAHCIYRIDK---------- +> +---------------------------------------------------------------------------YNFDTVASLVDLPGAFIIGAGAGR--LCTINCELMPNIVTTSDCTHGDNKSRAAMICPDDGILMIKQY--D--LNEFYILGNLLACEGKQGPVIEVKVSKRSGKENFVTNMRETLKAHYGDKPVGLGGTFLIESGKAKLHVMELDYYTVPLNSDADVDSWLKFREADAPLVCLSVLISHDPGLSLRVEHTHCFRQFNEGGHYHYDTTPDEVSYHGYFVPAEYMYRLDRPP-------- +> +-KRHRLYQPSLGSISLAITEGLQKNFKQVTVKVVKCPDLREWA-NLSAKGICGNTRLIDAGGVPYMFPEMQATVNYCMQDLIHACDMKAGLVIGAGAADPKVIGKNGELVPNLKVPS----GANHTHYAKMENAGNDVPVCRT---YASDFCGCLCNLFVSDGCNDSVLYIKAKSRIGKLNFTNCIRESLQNVKGDKQIGMGGVIKVSQGRIKGHVMP-DFMKECVDIMIAVDNWLHFYECGPNLVMMATLISGDPSMHLRVEHTHFYTLVNEGGHYHYDTTPDEIEYEAYLNTAEFVYRVDDA--------- +> +VKKVKLHIPTEADLLFCLEPALENNYQQVEIDFVECPDLSQPPYNLASEGLCGSPKLAEAGGVPYLIPGPANEHVYSYRDVCKIVGLPDGLAIGATCSSPESVKSCAEVMPNTSAE------KNLTHCARVNNDGESYDCKLY--G--SNEFTTLGNLCISKGQRGRCMKIKVKNRIGNGSLTICLQDALKEKFK-LPVGMGGVFVLGKTKTKVHVMPQRFSQKPLKTSKKIDEWLQFYETTAPITHLATLISRDVDFSFRTEHTHCFSKHNQGGHYHYDVGDKEVEYEGYFVFPDTAFQIDWP--------- +> +-KERSMKTPTLSEIAEVLQNGMQPLFHRLKVDVTSCPCLTKEPYNLAGVGLCGNTAIIELGEKPTENVSDWKDRTCDIKSVLKTN-CSDSFVIGSSYATKPHMPYYGHLIMNATYRA-PESFTNASRIVFIETGNGQRRIETVTDP-NQLTCTHNGCFFVSEGRPGNVVRVRAKGRKMITDIITSMQTVLYESFGTETVALGGVLRMRYGQVACNVML-DEYPDEKLQFVNFYFQQQYINLESDMIAVGVIFDDLPILDEERSEFHCFSDHGTGGQFISDISPDTTEYEGYFNVVKK---------------- +> +-ERAPLHVPSLEEVQEGLARELQDVYKRTDVSVEECPDLQK--WGLAFSGICGSERLLDVGGVPNLLDPAKHGISFALEDLCKCGGLPNGSVLGAAAGDANFVGKNSELMPCEDVDAK----SRSTHVAKLDDGG-QCVLQAY--D--HGRMGFLGNLFLSEGKGGKVLKISVTSRRPDGDFTAALRSALGRAFPGRAIGLGGAFKMISGRFKAHVMP-DFKETQMEDGPEVNAWLKFFEFGPGATFLSTLLTSDPKLNLRLAHTHFFNETGQGGHYHNDTTPEDVTYEAYYSPAHYVYRIENAYD------- +> +--EIDVTPPSKRAIANILKDGLKEHFKEVSVEWVDCPDLRKKPFNLAAPGLCGKPALMQVGGLANVYPWQQIHKTYNIKHLLTEFGYNEKLVIGAGMCKNPLTTLNCELYMNTLYSPRMISVFNRSRTLFYLSKT--CRTGPYKIHNNLHECSMYGNFFISGGKPGQVIKVYAKKRIGSLDFISAMQSSSCYGRTKYMIDLGGTFVVNNGKVWHHLMP-HKAATILRDFRSIHQWLRYRCMPTPFTAVGTFSNRIRVLNITKQHFHTFSSYNTGGHYYIDALEKATEYLGYFCPAKKFYCVDPVNVN------ +> +--VYPLESPTIDEVADALRDGLAKVFKKIDVDVVDCPDLRQAPYLCSKPGLGGKGSVVDCGGCALLYPKVDITKEYDMRQIASIV--DNYHVGGAGACAYSVTGQNGELAINCADEG-----DPHTACGIVCEDS---LPEKKNYH--SYLSGPLCNVFKCSGAPGKVLRVHAAARMDPSDIVETMKSILETAFPRDVLGLGGVVLVKKGKVMIHVMH-DFTVKPIRSQKFISEWLRMKEADTPFTNYTVFVTNPPTLDLRPSHTHGFND-KVAGHYHYDTTPLRVDYECYLQLADNIYRVDRASQEPDFD-- +> +-----------------------------------------------------------------------------------------------GAGPWPHMNTNCELVANCLLTE-EKIIKNLSRVGIVGKNG-EALVKILPNS--ETRCCLLANFFACKGEPGPVIEIRCKGRKGTKDFITTLRTILEHNFN-EVIAMGGVFVILKGKAKQHVMP-DFSETPLNSDEDLNNWLKFYEMPAPLVAVGTFVSKDPGLDLRIQHFHSFG-ENEAGHYHYDTTPDEVEYLSYLLPANVLHRLDKPEVTHNIGRD +> +VTKHPRDPPPLDELAAIIERSLLCNFSTASVSVVQCPDLRHAPFNLAGSGLSGNTRIADIGGQQHLFPQPVLDAKYSMLSLAKDMEMSSAFILGAGAAPFQDIGQNAELAPNLSWEANSLNVESGTRVIKISQDN-SPKCEQL--P--STNCALMINLFGSNGETGAVLKISARTRTGEENFTNCIRNGLRDAYGSRPISLGGAFLLKSGSAKFHIMP-DFPAEPFRDRQQLKEWLTYHVFDAPV-------------------------------------------------------------------- +> +--KMGLFQPDLEHLAESIRKALTENFESVTVTVVSSPNLQE-WCGLAERGISGNCRLVDLGGVPYMMDPKYHHITYQLPDVVKTCDMTGPLVIGSGAASPTVVGKNAELMVNALIPGEV---------------------------GPSEETGCLMNLFLSEGKPGKVIYIKVNKRKGRLNFTNTIREGMKSCKGEHQVGMGGVFKVNKGKIKGHIMP-DFCKKKMDEKEEVDNWLRFYEFGPHLLMLSCLLTDDPSLHLRLEHTHFYSDTHEGGHYHYDITPDEIEYEGYFSLAEKIYRVEDAY-------- +> +---VDLPLTTLSEVASALQSDMNTFFREVNIDIVRCPYLTTKPFNLAGIGLNGNPYILNVGQIERFFPTPQPDATWNIREILSNS-CRDAFIIGAGYAATPYMPYNGHLIMNATYRA-PATFTNASRIVFADANNEQRRIKTIDNP-DHMMCSFMGNFFVSEGKEGNVLRVRAKRRESNLDIITIMHDIIYRHFQNRFVALGGVLRMRNGRVAHHLLA-EEYPSQISTFDDLIKRFQCIPLESDLIAVGSFANLPPTFENRFYQFNSFSDYGAGGNFISDTTNYMTEYEGYFNVARKLYSV------------ +> +-TKHLRDPPPLDDLATVIERSLLSNFATASASVVQCPDLREAPFNLAGSGLSGNARIGDVGGQQHLFPQPVLDAKYSVLSLAKDMEMSPTFILGAGAAPFQDIGQNAELAPNLSWKASSLSLENGTRVIKINQEN-SPKCEKL--P--STNSALMINLFGSDGETGPVLKVSARTRTGEENFTNCIRNGLRDTYGSSPVSLGGAFLLKSGSAKFHVMP-DFPPEPFRDRQQLKEWLSYHVFEAPVV------------------------------------------------------------------- +> +---FPVRRDHIVEIARELKRGLQPLFGFVDAKVVECPNLTRKPFNLPRSGISGENTIACVGSHDYILPSISCRKQYDLMDVANACKVRAGEILGGGTGPYPTTGHPCEMVAELCYCN-GSISCNRTLHAYSDKSGS--APNLIKAT--DTKFHSSAQLFVSEGNEGWVIEVIAKRRLCEGSIGKFLHQALQSRYGDEPMALGGVFLLEGSGAKYHVLS-ELPNEPYHTFPDLKSYLKCFEMKAPIIGMGTVLSHDPDLGLHMHSFHIYNERNVAGHLETDTDPEAASYRIFLHPASHICRMDKP--------- +> +---------------KALQKKLLENFAEAQVDVVDCPNLAEDPFYLNKEGIGGSPSLISCGTVTNFVPKLKLERTFNLKMFPPLAGLESASFIGTGMYHCHESGYLPETTVNASISK--GELDINKTVGYMDKISKKHILKSAPIT--LAEFPCLLDLLFSKGEKSKVLRVHCSKRTGEFSLPSILRNGLRTHFPDKLIGLGGTFLVKQGMATCHVNH-LSENDQFREEEFFKDSCTFINMSAPLVAVGEIISQDPGLELRLEHFHCYSNHGDGGHFHYDTTPESVEYLGYFSIAETLYRIDYPEN------- +> +-EKAKLYVPKLSDIKIALQDGLSNNFRKVNVSVVDCPDLTK-FVNLSSKYICGSTKIADVGGVPYMDGEPYCYTTYNIDNIIKHCDMKNACVFGASAASSFILEKNAELIPNTKVPCGP----INTKYASLDNNPDTPYVSHY--P--WNQTGCLANLFLSDGKPGKVLHIRCEGRTGDINFTNCIRESLKNGYGNGEIGLGGVIKVLKGQIKGHIMPNHFPHVKIPNET---EWLRYYKCGPNLAMFSVLMTDNPNNHLRLEHTHFFNDVNEGGHYHYDLTPKSIIYDAYFSVANDIYQIDNAYNN------ +> +----PLDVPSLTELQEGLEEQLKENYESVDVSVEECVDLTL--WGLAFPGLCGSESLVDVGGVPNLLDPAFQRLAYPIEEICVCAGVPNGCALGATAADANFVGKNAELIPCESVGD----RSRTTQTAMLDDDDERPELIAY--D--HGRIGCLGNLFISEGKPGRVLKIRVAKRSERGDFVAVLQNCLVKAFPTKHIGLGGVFRLDSGAVKAHIMP-DFKKTVMIDGPEVESWLKFFEFGPGGTFLSTLLSSDPQLNLRLSHTHFFNATGEGGHYHNDTTPKDSQYTAYFMPAKYIYRVENA--------- +> +---------------GVLEKALLKNFKEASVTVVPCPDLTREPYRLAAPGLNGQTAIADVGGTKNMHYLENNKHHFDIKDLSHQI--GLPFFIGAGATKLSFRKDNSEMMPNLDVSK----GVNLSLEAYVGKDG-VGQLVDY--P--HTEFSALANFFVSEGKSGPVLKIKAKHRIGKLNIVTAMRQALVEHYGDKQIGLGGVLLINNGKIKSHIMP-GFPPCDVNTGQ--IEWLTYYEVSAPITCLSVFVSHDKHKDLRIEHTHFFSNRKDGGHYH----------------------------------- +> +-KTCATFVPPMDEVCKALEKNMAGDFETVECKEVWCPDMREAPYHLAAQGICGSPRLADVGGPPYLVPTVQRDKLYNLKDIAEEVGLPGATFIGAGAGSSRLTGTNCELMPNSNLAT----GEIKTHFAKMKDG--KPELERY--M--SNEFGLLANLLATEGKRGKVLQVKATGRIGDKTFVNSIRLALAKEYGEKPVAVGGVFIIGKGKAKLHVMP-DFSTTPLTTDAEVDAWLHYYE------------------------------------------------------------------------- +> +---IETLKPSNSELLPIVESALKSNFKDVTVEVGPCPDLSVEPFSMTSSGFGQNLVIAEVGGPGNLFPKINKEKEFDLKEICNTCQSPFSFVFGPGAGPWKVVGRNCEMVADANFAT----AKVATKIASLPPGYPPYKMGVI--D--SPKFSLMANLAVSEPGPGEVLHCKCSVRIGKDNFPETIRKALAKHYGKRCVSLAGIFLLGEGEAKLHVMP-DFPGCQFSSTEEVSLVFK---------------------------------------------------------------------------- +> +---IDLYVPDKTELAIVLQNELSTDFEEVKVEWVDCPDLTQEPFNLAAPGLCGDTALLDIGGIWNLFPFPIKDKIIYFQSILEKLDRTQSLIIGGGLRTERPTNLLGELIMNVLAANETMTVKNKSRFALIKLNRKHFSLKFVTDP--NPYCNIYGNFFISKGLREQVLKIHVKHRT-GRDFIVSLQHAIKRFSKSQLMGFGGTFIIKNGKTIQHIIR-NYWEVPIRKKKDIHNCIKYLKINSPIVAFATFVSSDRKFDVYLNQWHVHANSNDSGGYYHETVPNNTEYLGYFSPATKLYRINPVSEFDEM--- +> +--RMVLDVPDLMEIQAGLEEQLKESYESVDVSVEECVDLRR--WGLAFPGLCGSESLVDVGGVPNLLDPNFQRLSYPIEEICVCAGVPNGCALGASAADANFVGRNAELMPCESLRD----RSRTTHTAKLDDNDERPELVAY--D--HGRIGCLGNLFVSEGKPGRVLKIRVANRSELGDFVGVLQNCLVKAFPTKHIGLGGVFRLDSGAVKAHIMP-DFKKTMMTDGPEVESWLKFFEFGPGGTFLSTFLSSDPRLNLRLSHTHFFNTTGEGGHYHNDVAPKDCQYTAYFMPAKFIYRIENA--------- +> +-TTLSTKVLPLSQIAQVLQDGMAKKFREVKVDIAACPCLTRQPYNLAGVGLSGNPSLLEIGGHANFVSNYDYDPTWKVQNMLASG-FFDSFIFGSGYAAKPNMPYNGHLIINATYRA-PSNFTNASRIVFAEASNGQKRIEMLTDP-NQMLCSYMGSFFISDGRPGLVLRVRAKDRISTLDIITIMQNSLYEHFGKHPIVLGGVLRMWNGRAVYSLMSEEYPQRQIHEFSDFNKWFQYHEMKTEVAAVGILTNRKPDLEQRRNQFHFISDYAASGEFIGDTTPDETEYEGYFNLAKKYI-------------- +> +-ESASLYVPELDQLAEMLEESLKANFEIVETAVVDCPDLQK--WGLAAPGICGNPRLIDVGGVPNLLPKYHGTAFFSIPNVAETVGLKGAYVYGAGAASSRVVGVNAELMPTEHVGKN----CRCSRYSKVLEDG-SHTMEKY--E--SSEFGLLANLVACDGKPGKVVMVRAKKRLGETNFVTCMREGLAKRFGTRQIGLGGVFKVKSGKVRGHVMP-DFKKTVMVDGPEVDEWLNFYEMGPDLTCLSVFLTGDPGLDLRLEHTHFFSQTNEGG-------------------------------------- +> +----------------LFQRKLADYFAEVAVAVVECPDLKKEPFHLASSGLSGSPAACDVGGVPNLAPLARTDKEYSIPRICHSLGYGQGFFVGAAAGPFKCVGVNSELMPNVLVSGGKATVVNETHCAKLADNEKGYQLLKMVDQ--AAEFCLLGNLFLSEGKPGSVIQVKAKRRVTETNFVTAMRNILKEEYGCKTVSLGGVFLLKSGRAKLHIMP-DFSKAPLCSDDEVNNWIYQQNKDRPL-------------------------------------------------------------------- +> +--------ISIEEVAVAIKEGLTDIFKNVKVGVVDCPDLREAPFFCCKPGLGNPHEVVDCGGVALLYPKVDLSREYDMRQIATIVDEHHH--SGAGSCAYSVTQQNGELAINCSEEG-----EPHTECGTVGEDT---MPERREYH--SYLSGPICNVFKCTGAPGKVLRVRAAARMDPSDIVETLKSILEKAFPHSILGMGGVVLVKKGKVMIHVMH-DFTVKPIRTQKFIDDWLRMKEAETPFTNYTVFVTNPPDLDLRSIHTHGFND-KMAGHYHYDTTPLRVEYECYLQLADSIYRVDRAPQEADFQ-- +> +---IDLYVPEQTELATVLQNELSTDFEEVTVEWVDCPDLTQEPFNLATPGLCGDTALLDLGGISNLFPFPLKDKIYFQNILQKVLDRTQSLIIGGGLCTKQSNELLVELIMNASFSNGTMTVKNKSSFASIEITQKYFVLKSLTDT--NPYCNIYGNFFVSKGLREQVLKVHAKHRT-GRDFIVALQHAIKRFSKSQLMGFGGTFIIKNGKTIHHIIK-NNWKIPIRKKKQIRYCIKYKNQTSSVVAFATFISADRKKDIYFNQWHVHAKSNDGGGYYHETESNNTEYLGYFSPATKLYRINPVPVFHEM--- +> +---------------------------------------------------------------------------------------------------------------------------------------SGYLTRRLPPT--ETRTALLGNYLLCDGRPGKVIKVVAKKRIGESNFITAIRETLKNHYGEKVVGMGGTFVVRAGRVKHHVMP-DFSAAPLCSDSDVDAWLHYFEMRAPITHVGTLVTGDHGLDLRVQHFHGWGEHGDGGHYHYDVTPASVEYEAYLTPAASVVRVDAPATTHAIGRD +> +-TQLRLSPPFLEDIAQTLAKALPSNYITSSATVT---DLRQAPFKVTGEGLTGSETAADIGGQVDLLPQPYLHKTYSLIETAKLMGLSPGAIIGAGAGPFLVDGTNSELAHHLSWGNGFDSVTNLTRAAQLRKEGSALPVC--CPLSGSTDSGLMMNLYGSKGLPGPVIKPSARGRQGDSSCADFIRQSLAKAYGDLQVSLRSVFIIKSGKAKFHVIP-PFPKVKFRNQEHLDGWLSYHTFGGPMIRLAVLHCGDPEKGIRLEHTHCYSERGEGAHYHYDLQDSEVEYERYFNTIKTFHQINY---------- +> +-ERIPLHQPNLHDLANFIRSNLKKHFLDVKVTVTKSPDLSKYPWSLSSPGISGEPTIVDVGGEHHQVFDYANKLVFTLEELAESAGADEAYFLGAGAAPRSSVGCNGELIPIDNIYTN----VRRSQLATVKINAMGVAESSALTPYNSSEMGFLANLLMTEGKTGEVLEIHVSKRISNESFTECIRQVVAKEFENEPIGFGGVFRVNKGKVKTHVMA-DTGGKTL-TAEEVQEHLKIFEIGPDLTAATVFLTKSPKNKVRLEHTHLYNQKTKGGHYHGDTTPKEISYTGYFTLAKSLFLVDRD--------- +> +---------------------------------------------------------------------------------------------------------------------------QETRITRTHDEDGSYETLRLPAS--ETRNAVLGNVFICDGQPGQVLRIKAGVRRGEKNFVTCMRECLNSAYPDKAIGLGGVFCIQKGTAKFHVMP-DFSPCPINNDDEVNKWLKFYSMSAPLTVLSVLISSDPGLDLRVEHSHGWGEDSQGGHYHYDTSPDTVQYEGYYNIAQACYRIDRPVDTHKFGRD +> +VEKKHLHTPPLSEIADYLNEGLKSNFQDVKVEVVDCPDLTQQPFTLADKGLNGNPKLVEVGGPPFLLPLVQKDKVYDVKDIAKLAHSDPAFVIGAGAGPHPYIGKNCEGVYNLKINN--DTIEQHTRISKVVEGSEKPVQEILPNT--ESRVALLANFFVSEGRPGKVLKVFARRRIGADDFIASIRKTLVSAYPEQLVGLGGAFLLKE-------------------------------------------------------------------------------------------------------- +> +--------------------------------------------------LSGKAIICDVGSFDYLLPVPKKDKHYDLLDVFRSAGVAAGAVIGAGAGPFFLTGSNSEMVINISSES--GVVKNGSLFGLYDKENNKPLLTKA--D--NTKFALLGQMFMCEGKPGPVIELNVSGRIQDGKFDAMIREALHVKYGNNAVGLGGVIVQEKGKSLYHVLP-EFSQEPIDSGEKLRNWIKMFEMESPVISVGIAVSHDPHHGLRLEHFHCFNNQTNCGHCHFDTYGPTVSYRCYFSIANHLLRIDQPSKS------ +> +-EVKDLYVPPIQDVAEVLNKSLRSNFEEVNVEVVDCPDLTQQPFTLASGGLGGNPKIIELGGNPYLLPVVHREKLYDLKGIAKLVESDPAFIIGAGAGPNPYIGVNCEGIYNLKISN--GSVNQQSRISKVDKNDDKSEQETLPNT--ETRLALLGNLLVSEGKPGKVIKVHAKKRIGDDNFITSIRKAVENAYKNELVGLG--------------------------------------------------------------------------------------------------------------- +> +-TVIPLPTPSLDQLANMLHQAAAANFANVSAKVVDCPDLRE--WGLSFKGLGGNPKLADVGGVPFINDPNYHDVTYELHEIMRQAGSAEGCIMGSAAASRSIVGRNAELVASLDSTA----GQSGSFFAKIQDGK------QVADHYYSTTVGGLGNFFISDGTAGKVVELRVSKRTGDLNFVTALREGLAKQVGSAHIGLAGVFTQPSGSFKYHVMP-KFKKTRMVEGQEVADWLHFFEAPGQTTTVTTFLTGDPGSNLRLEHSHFFDKRKIAGHYHYDTTPDTAEYVAYLVPAASMHRISN---------- +> +-ERIALHVPELKELAEVIANSLRPVYRNVSTRVITCPRLTDESWSLPSPGISGSNAILDVGGEHHQVEAYANELSFGLEEVAVAAELRGWYFLGAGAAPRGCLGCNGELIPFDNLHS----GTRNSQLATVERDEGDERPGLCKYN--SSTMGFLANVMSCEGKQGDVIEVKASVRTSSESFTECIRRGIASGYADEPIGLGGVFKVVKGRVKVHVMA-DTAGRVFTDSSQVQEYLKMFTIGPDLTCATIMISKQPSGKVRLEHTHLFNACTEGGHYHGDVTPQEVEYVAYLVPTEELLLIDKR--------- +> +--QIHLFIPEGAKLAAVLQNELSTDFEEVTVEWVDCPDLTEEPFNLATPGLCGDTAIFDVGGVSNLFPFPQENKIYFFKDMVRTFNRLDTLIIGGGLTKVSEEKLLGELIINASFDERTAVIKNKSRFAFLKTLNQKCKLIPL-IDNTNPKCHMYGNFFFNNGLREQVLKIQAKNRV-SRDFTVALQRAISRFASGDLMGLGGTFVVKNGKTKHHIIQ-NDWKGPIRKSTEIRKCVQFCEMPTPVVAFATFLSADRKIFLTRWHAHSYSAF-GGGHYHETKQNSNVEYLGYFSIATKLYRIDPVPMFN----- +> +-TTHPLPPTSLSNLISPLLTSLKQNFTDATISLVPCPNLTQPPFHLAAPGLSGHEAIVDIGGPAYLHPVPDFSKKYDLGRIVASLSSGEELAIGAGAGPFHIVGQNSELIPNFYISASGNVTKNLTHYAKIDPSTQTCIAGPVPGA--STAGALMANLFLSDGDPGPVLRITARNRIGDKSFTEAMRMGIEER----EISMGGVFVVEGAKVWAHVMP-DFCGERLE-DAEVGKWLRFFEWGGELVFLSCFHGVDFGVGVRVEHTH----------------------------------------------- +> +-----LHKPSLEEVAEVIQKGLAKNFTTAQVRVVDCPDLSAAPFDLADKGLSGTPRILDVGGPDFLKPFPQKDKKYTFAQVSELGELPGSFIVGAGAGPCHNVGTNCELICNVKLGK---ETINKSHIVKVNEEDGSYSIHEE--K--SGEFSLLGNFFLCEGKQGKVLEIKAETRTGSENFVECLHKTLTNHYGDKPVGIGGTFLLQKGKAN---------------------------------------------------------------------------------------------------- +> +----------------------------------------------------------------------------------------------------------------------------------------NYRLDKC--K--YPEFGLLGNLFISEGKPGKVIEIIVEKRLGKENFPESIQKILRENFPNKPISLGGVFIIEKGRTKLHIMP-DFSPEPLRTNDDVDKWLRYFDMDPPLICLTTLHSIDPGLDLRMEHTHCFSDHNQGGHYHYDITPDIVRYTGYLQIVEAIYRIDRPK-------- +> +-EEKPLYVPPLSELQNVIQGALNTNFANVSVSVGPCPDLKAKQFGLVESGLGGKPTLLEAGGPPFLLPLVQRDKLYNITEITRQIQGPGKFAVGAGAGPWPIRGSNCEGIFNLSVSE-KNELTNGSYTATVRGEKEECVLEKIPHS--EPRCALLLNLFLSQGQPGEVIKITAKQRTGEQNFIECIRKGLEEYYGDKVVGLGGIFLIKK-------------------------------------------------------------------------------------------------------- +> +---INLDVPKQTELATVLQNELCSDFEEVTVEWVDCPDLTQEPFNLAAPGLCGDTILLDIGGISNLFPLLTEDKIFKFTNILQKLDRIDNLIIGGG--QIKQSNTLGELIMNASFSNEMTTVKNKSNFAYIEMPQKKFVLESLTDP--NPYCNIYGNFFVSKGLREQVLKVHVKHRT-GRDFIFALQHAVKRFSKSKIMGFGGTFIVKNGKTIYHNIK-NNWRIPITMKNHMHYCIKYREVTSPMVAFATFVSADRYKGTYFNRTHVHVKSNADGGYYHETEPDNTEYLGYFSPATKLYCINPAPVFHEM--- +> +VQKVPLFVPGLKDLASALETTLTPHFLNVSARVVRCPDLTSSEWGLAAEGLLGENKLYDVGGEHHQVKPYANRLAFGLEEVARAGNVTEAYFLGAGAAPRASVGCNGELIPIDNLYGN----VRKSKLATVEIDSHGIPRAALQ-QYRSSKMGFLANLMSSHGDRGDVIEVRVSRRISTESFTDCMRRGLSETYRSNPVGLGGVFRVLNGQVRTHVMA-DTQGKVFTESAQVQEYLKMFTMGPDLVAATVFISDQPRSSVRLEHTHLFHSETTGGHYHGDVTPSEIEYLAYLVPNHELIIVDRI--------- +> +-TRHRLFVPKLSDLATMIEETLTPHFQTAQARVVPCPDLTKKGWQLASKGISGSNKLFDIGGEHHQVKKYANKLSFTLEDIAGAAGLTDSYFLGAAAAPRSSVGCNGELIPIDNLID----GVRLSKLATVNETDP-TGLRVSLSPYHSSEMGFLANLMSSEGSPGQVIEVRAKVRLGDASLTDCIREGLAEKLKLPPLGLGGVFKVVSGQVKTHVMK-DTGGRHFHHSSEVQEYLEIFTMGPDLVCTSVFLTGEPSDRVRLEHTHLFKDLQKGGHYHGDVTPDEIEYVGYFVPNEELLVVDRDVEAVH---- +> +-SKTRFTSPSLNELAAVLRSGLMNSFDEVNVEVVECPNLKSKPYLLSSEGICGSPRALDIGGVPYLIPSPCMEKIYDLSKAPSWSELSHTLMVGAGAGPSHVVGKLAEMIVNVSLDE-SGNVENQSRICKIDDKTGKHVVQRV---ENSTDCCHLTNLFASEGKRGKVIEVRASRRKPDDDFISSLQKAVKSRYNSQPVCVGGVFVLTRGRAHIHVMP-RYSDVPLVTDAMVDQWLKFI-------------------------------------------------------------------------- +> +--SAKFNNPSLEILAEALKKGLKANYQEVTVEIINCPNLRE--WNCPSEGISGNERIIDVGGEPYMHDKQFIGTEFDYEEIAKNIGSEKSYALGAGSGAMSCLGHCGELIINENLITN----ESNSIIAQVNKNK-ECVTKKY--T--EKKHGGLANIFFSDGKIGKVIKIKLKKRIGKGSLPQAMRSALFENIINRHVALGGVFRVLHGGVKSHVQP-DYEDIKYEYYKCTKDFLQFYEVGPKLQCYSVLWTGDPTGNLRETHFHSYNNKPEAGHYHFDVTPNDIEYECYFNIAHEVFRVNNIYKE------ +> +-------------------------------------------------------------------------------------------------------------------------VQKTTMARTMDDADETYKLLQLPKE--ESKMSLLGNLFLSEGKQSQVLEIKCRCRSGKQNFVSCINAILKEAYPDKCIGIGGVFCATKGKLKIHVMP-KFSEVPLKTDKDVENWLNFYEMDGPFTCLSVLVSNDPGLDLRLEHSHGFNAQGQGGHYHYDTTPDIVEYTAYYNIAEVCYRVDRPNVTHMVGRD +> +----------LNELIEPISNSLLKLYENVEIKVINMPDMSSPEFKLAAKGLCGHTRLADVGGVPYMNDPKYHDVTFQLTDIVKVCGLDKALVIGAGAASPTVVGRNAELMPNTLVPGNNENKETESKEESNNNE-NEVPFVGI-YP--SEETGCLANLFLSDGKQGPVIYLKVSKRKIDLNLAVCIRDALNEFREKEQIGMGGLFKVSKGKVRAHIMP-DFANFVLEKPEQVENWLKFFDMGPELAMFSTLITGDPSMHLRYEHTHFHSKTHEGGHYHYDIE-KDVEYEGYFNLAEFIYR------------- +> +----TFANHSLEDIASALKKGLSENFKTVEVEVEDCPNLRD--WDCPSEGISGNQKIIDVGGEPYMHDPNFIGAEFDYQEISKMINSEKSYALGAGSGAMSCLGHCGELVINENLITD----ESRSIIARVSPDK-KCIVEKYT----AKKHGGLGNIYYTDGKQGKVIKIKIKGRSGNGSLPQAMRSSLSNNLNNEHIALAGVFRILEGKVRSHVQP-DYKDIDPKQMKCVKDFLQFYEVGPKLQCYTVLWTGDPGLNLRHTHFHSYEHDRDAGHYHFDVTPDEIEYEGYFNTASEVHRVNNIYKEL----- +> +---EKFDTPSLDKVAEALNLGLKENYKEVNVEVVDCPNLKD--WGCPAEGITGNEKIIDVGGEPYMHDPKFIGTEFDYEEISKKIGSEKSYALGAGSSAMSCMGHCGELTINENLITS----ESKSIVARVDKNK-KCIVQKY--S--ARKHGGLSNIYFSDGKKGKVIKIKINIRTGKGSLPQSMRSTLIKHLKNKHVSLAGVFRILKGKIKSHVQP-DYKDIKVDYYKCTKDFLKFYEVGSELQCYSVLWTGDPKLNLRHTHFHSYNNEKDAGHYHFDVTPKEIHYEGYFNISKEVYRVNNIYKE------ +> +------------------------------------------------PGLSGKPCIVDVGGIDNLFPRVNCEKEYCLRECAERSGRKNFHLCGAGSCGYSLIKCNSEMVVNAGHDQ------IKSLCARMVDNHTKICVEPY--N--SYKCSALANVFCSKGEAGKVLKIYVKRRIGEPDFVGCVQQVLKDQYGEQPVSVGGAFRMISGKAKVHVMS-DFTQNPIQTQEFIKEWLKYVEAPAPMTFMTVCTSVSPGLGMRLTHTHGHSSPKIAGHYHYDLSPDEIEYEGFFGVAEAIVRVDQVSQDP----- +> +-EKAQFTKTSLEQISEALKKGLQKNYKSVEISIVDCPNLKQ--WDCPAEGLSGNQKIIDVGGEPYMHDKKLIGAEFDYEEIANKIGSEKSYALGAGSGAMSSLGHCGELVINENLITN----ESRSIIAQVDENQ-KCKSSKY--T--ARKHGGLGNIYYSDGKPGKVIKIMIKGRSGTGSLPQAMRTALKENLSDNHFALGGVFRILNGKIRSHVQP-DYDTIDPKQMKCVKDFLKFYEPIGPFQCYSILWTGDPKLNLRHTHFHSYKGTQDAGHYHFDVTPEEIEYECYFNIPEEVHRVNNIYKE------ +> +-EKADFKEISLDKISEALQSGLKKNYHQVEVSVEDCPNLKE--WGCPAEGISGNERIIDVGGEPYMHDPKHLGAEFDYEEISKKIGSEKSYALGAGSGAMSCLGHCGELVINENLITS----ESKSIIARVGTN-KECIAEKY--T--ARKHGGLGNVYYTDGVKGKVIKIKIKGRSGDGSLPQAMRKALSDNLPNEHIALAGVFRILNGQIKSHVQP-DYADIDAKQMKCIKDFLQFYEVGPELQGYSVLWTGDPNLDLRHTHFHSYTKENVAGHYHFDVTPNDIEYEGYFNIAKEVHRVNNIYK------- +> +--------------------------------------------------------------------------------------------------------------------------------------------------------SLLGNLFLSNGEGGQVIKVSCKKRTGGDNFVSCMRKCLEKEFPTESVGLGGVFCAQKGQLKIHVMP-EFSSEPLKSDSDVENWLNFYTMDSKFTCLSVFVSRDPGLDLRVEHTHGLNEKCQGGHYHYDTTPEEVEYTGYFNLAEYCYRVDRPKVTHMIGRD +> +--SAKLFVPELEELATMLQTALKDNFETVETEVTECIDLTK--WGCAAPGIGGNCRIIDVGGVPNLLPKHHKTAIFQLPTVAEQVGLKGAYIFGACAASHLVVGVNAELMPTEHISKN---CR-CSKYAKVVEDG-SHIMEAY--D--SPEFGLLGNFVACEGKTTPVVKVRVKKRKGEDNFVTCMRKGLAKALEESKVGIGGVFKVVSGKIHGHVMP-DFKKTVMIDGPEVDEWLNFYEMGPDLTCLSVFLSGDPAKDVGKHFTLSFS-------------------------------------------- +> +------CQPPLKYVAAVLQAGLRENFAEATVTVEECPHIRQAPWGLAGPGLGGKTRVMDIGGVPYLMPSVQRERLYDMKDYPRMTGLDEGLVIGAGAAPWPFLDRNAEMMPNLFVKA-DGSVLQETHIARTHDKDDSFETIKLPKE--ETRNSLLGNLFISSGEPGPVLKIHCKGRTGPKNLVTCMREILAEAWPSETLGLGGIFRIVKGKAKFHVMP-DFSPCPIPVMQRLTS------------------------------------------------------------------------------- +> +------------------------------------------------------------------MPSVKREKLYDMKDYPELTDMKSGLVIGAGAAPWPFLDRNAEMMPNLMVKE-DKSVIQETHIARTFDEDGSYTTMKLPAT--ETRNSVLGNLFICEGTSGKVLKIHCKKRTGDKNFVTCMRQTLVDQFPDKSIGLGGVFNIVAGKVKIHVMP-DFSPCPIDTDEEVNKWLKFYEMSSPFTVLSVFVANDPGLDLRVEHSHGWGK------------------------------------------- +> +IERKSLDRVPLEELAQVLNQSLKDNFDYVNVEVVDCPDLTGHPFTLAKPGLDGSTKLVEIGGVPYLLPLVKREKIYDLKKIAISVKSDPAFIIGAGAGPHPYAGVNCEGIFNLKIEN--GTVDQQTRISKVDPNDKRSFQSTLPNS--ETRVALLANLFFSEGKPGKVLKVHTKKRTGSQDFIASIRRSLVNAYPNK-------------------------------------------------------------------------------------------------------------------- +> +------------SLIQAIENELKQVYKQVNVRLVPNNDLSAKPWNLAGSSLGTNGVFCQLGGAKNVEYKQGHSIRFDISSVLDQLHIKNKLVIGPGAGDLTHLTINGELVFNMTLNQYNKVITQRSYSSIVSKEE-QPYQSSY-E---PKTCGPFQHIMISSIKSAVLIEIDVQERLTDNNFISVIRRSLKQ-YSKEPMALGGIFRVEKGTVKAHIMP-DFLDEDLTTKQQVDQWLKFYDMQAPLNCLSVLLTEDINNGFRLEHSHFFSDHGQAGHYHFDITPKEVHYHGYFILCDEAIIVDP---------- +> +------KKFKLEEISNALEKGLSKNYDSVKAEVIDCPNLRN--WDCPSEGMSGNQRIIDVGGEPYMHDPKYLGTEFDYFEISKMIGSERSYALGAGSGAMSCLGHCGELVINENFITK----ENKSLIARVGKDK-QCIVEDYT----ASKHGGLGNVYYSDGVKGKVVYLKIKKRIGKGSLPQSIRAVLSENLKKDHIALAGVFRVLNGKIRSHVQP-DYKDIKHEYPKCTKDFLQFYEVGPKLQCYTVLWTGDPELNLRHTHFHSYEHKNDAGHYHFDVSPDEIEYEGYFNIAQEVYRVNNIYKE------ +> +IEKAKLKKIDLNQVQKALQLGLSDNFKEVKVEVVDCPNLKD--WGCPAEGLSGNEKITDVGGEPYMHDKRFIGTEFNYEEVAKEIGSGKSYALGAGSGAMSCLGHCGELIIDDNLIT----REIKSIIAKVGNNK-ECITENY--N--QRKHGGLGNVFYSDGKKGKVLKIKIKGRNGKGSLPQAIRAALIKHLDDNQIALGGVFRIHNGKIRSHVQP-DYEDIKHEYYKCTKDFLQFYEVGPHLQGYTVLWTGDPKLNLREEHTHFYDDKKISGHYHFDVTPDEIEYECYFNLAQEIHRVNNIY-------- +> +--SAKFNNPSLKDIVNALKKGLKANFQDAAVEIVDCPNLKE--WGCPAEGISGNEKIIDVGGEPYMHDKRYIGTEFDYEEISKKIGSEKSYALGAGSGAMSCLGHCGELVINDNLIT----GVSKSIIAQVGKNK-ECVSNEY--S--ERKHGGLGNIFFSTGLRGKVIKIILKKRIGKGSLPQIIRSSLIESIDNAHIALGGVFRVINGAIKSHVQP-DYEDIDMKLMKCTKDFLQFYEVGPNLQCYSVLWTGDPQLDLRHTHFHSYDDKKKAGHYHFDVTPNEIEYECYFNIAHEVFRVNNIYKE------ +> +-HRVKLHVPSMQKLASMMYRTLSSNFREVSVSVVQCPDLRD--WGFASPGLSGTNTIVDVGGEHHQVQSHANHLSFHLEELAIVIAEEDSYFLGAAAAPRASVGCNGELIPIDNLRD---H-VRNSKIATVEVSPDGHERAVL-DSYDSGEMGFLANLMASDGKTGPVIEVRAAVRLSEESLTQCLQQGLKDQMALAPIGIGGVFKVTRGRVKTHVMA-DTGGKTFTHSSEVKEYLKLFNMGPDLTAATVFLSRQPSKKARLEHTHLFSDMKEGGHYHGDVTPTEIEYLAYFVPNHHLLMVDRT--------- +> +-EKAKFTEYSLDKISDALQSGLSSNYKVVEVSIVDCPNLRD--WDCPSEGISGNQKIIDVGGEPYMHDPKFIGAEFDYEEISNMIGSEKSYALGAGSGAMSCLGHCGELVINENLITD----ESKSIIARVGKNK-ECIAEKY--T--ARKHGGLGNVFYTDGNRGKVIKIKIKGRSGEGSLTQAMRKSLSDNLKNDHIALAGVFRILNGKIRSHVQP-DYKDIDPEQMKCVKDFLQFYEVGPELQGYCVLWTGDPNLNLRHTHFHSYTKENVAGHYHFDVTPEEIEYEGYFNTAEEVHRVNNIYKE------ +> +---IDLFLPDKMKLAAAVENELSTSFGKVTAEWVDCPDLTQEPFNLAAPGLGGDTAILDIGGISNVYPEHIESKIYHFENIFKHLNCNQNFIIGGGLSRRLSDNHLGNLIMNATFSTENRMVKNKTLFAFVDEADVKFTLEMLTNP--LPKCHMYGNFFVNQGLREQVLKVEAKERY-GRDFIDALQHAFSRIYPDKLTGCGGVFMVKNARVVHHVMQ-NNWCSLFYNKLTIKESLRYWSVKTPVIALTTFLNTDRKFDLFLTRFQVHSSNNCGGYYHKAEDDEAIEYLGYFSPATKLYRIDPVPMYTE---- +> +-EHAELYVPELKRLSEMLEKSLSNNFESVEVKVVDCPDLRK--WGLAAPGLCGRPRIIDVGGVPNLLPKHHGTAFFDIPTVAKQVGLPGAYIYGAGAASSKVVGVNAELMPTEHVSES----CRCSRYSKVLEDG-SHMMDKY--E--SSEFGLLANLVACEGKPGKVVKVTAKKRTGDDNFVTCMRVGLKKQLDD-SKGIGGVFKVTSGKVKGHVMP-DFKPTVMIDGPEVDEWLNFYEMG----------------------------------------------------------------------- +> +---------------------------------------------CASQGLGGHTALCDVGGVPFLLDPEWQDVYFELRKILNVVGMPKATALGAAAAWNGRIGVNGELMPYASVNS----GTNTSHFSIVNKDG-DCECNHYPYL----EQGPLSNMFLCDGTQEDVIKIEVEVRTGDENLVSCIRNGLIETFNSRQIGMGGIFIVKKGKVKMHVMP-DFYPSMVDGDQVVKEWLKYYEVGPNLLCLSTMLTGDPDMHLRLEHTHFYSMPTVGGHYHNDVTPEIVRYIGYFSPAEYIFRV------------ +> +-----LYQPSLQELQKLLTVTLKKSFEDVVVKITSCPQLTKEPFNLAANGLHGNTAIIRCDS-------KTTQRKWNMNYFLQNF-PYDSFLIGGGFGAKPNLPSNGYLIMNATFSR-PEQINNASRLAYVRSLTDSGIVEIMKEP-DQMTCCTIGNFFMSEGRPGPVLEVQAKKRKSPPNIISIIGKILYSYYGNKLVGLGGVLLINKGEMLVSVISNKIPENQIISSNDLLNRVRAINCTSNITAFGTILGSKATFKLYPRHFYTFSENNVGGRFAKDVTPDETEYVGYFNTAEYLYH------------- +> +-------NHSLEDIASALKKGLSENFKTVEVEVEDCPNLRD--WDCPSEGISGNQKIIDVGGEPYMHDPNFIGAEFDYQEISKMINSEKSYALGAGSGAMSCLGHCGELVINENLITS----ESKSIIARVGSN-KECIAEKY--T--ARKHGGLGNVFYTDGVRGKVIKIKIKGRSGEGSLPQAMRKALSDNLKNDHLALAGVFRILQGKIKSHVQP-DYADIDPKQMKCVKDFLQFYEVGPELQGYSILWTGDPTGNLRETHFHSYTKENIAGHYHFDVTPEEIEYEGYFNTAE----------------- +> +IKEKPLYQPPLQEVVDVLSNGLANTFATVSVSVADTPDLTQAPYNLTSPGLTGDPKLVEIGGPPYLLPLVQRDKLYDLALLAKHLQRDPAFIAGAGAGPWPHIGVNCEGIINLSIEN--GKVDQGTRIVSVEPVTGLYLQRRLPNN--ETRTALLGNYLLSEGKPGKVIKIVAKN------------------------------------------------------------------------------------------------------------------------------------------ +> +------------------------------------------------------------------------------------------------------VGVNSELMPNLSWEG--EEVRNLTRYARIDEGG-GCVCERITEGKGSVDCGLMANLFGSDGAPGKVLKIVVSTRTGDKNFTDTIRDALKDVYGERLVSMGGVFVIKKGKAKLHVMP-DFPNAPFKDRGDVERWLRYFEMEAPLVCLSVFHSCDPGLELRMEHTHCFKEGRDGGHY------------------------------------ +> +---------DILEFYQNLESTLQKYFDSVSITLLNSSTLLETDFQLPFKSIGRNHKIVDIGGVPNLLNPEFHNISYSIDDIVQSIEIDSAAIFGASAADAVYLQTNGELMPVESYGSG--DRTIGSFSAIIDQSENGCCCKLQRYN--HSRIGFLGNLFVCEGQAGPLLKIIASKRKDEINFVSAIRNCLKELYPEEGIGLGGIFTMKAGRFKAHVMP-DFKDSVMEDGPEVNEWLEFFEFDSNATFLSVLVSQDPSMNLRLEHTHFYNETKQGGHYHHDTTPETVIYEGYFTFADSIYRIENA--------- +> +--QADLCTPGLEELAAAIERGLEAEFREVHASVSSCPDLRQPPFGLAIAGLGGNPRLADVGGVPNLLDPEYHHLSFSVSDIVRCTRPETAAVLGASAADARFLGCNGELMPVECLHSSRTDTPLRSTFSATLASDQSCSLQPYPHD----RIGFLGNLFISDGVAGDVVKVQARGHRSAASFMVAVRSAVAAAFPGKAIGLGGVFTMDGGEVKAHVMP-DFKATVMEDGPEVNAWLKYFRFDGSAAFLATALTRDPSLNLRLEHTHFFNATGVGGHYHNGFPAVDASYIAYLLPAAAVYRVENA--------- +> +----------REKLVETIEKTMKEIYQNVKIRLVSSMDLSGAPWHLASKNLGENGFFCQLGGAKNVEMKKGHHIRFDISSALDQLAIRNELVIGPGAADRTCLSINGELIVNLTMNQYNKVVRQRSYSSIVSNG--QAEQNSY--E--SQTCGPFQHLMISSVKPGILFEIDVEQRLSDNNFISVLRRSLKE-FSTKPMGLGGIFRIEKGTIKAHVMP-DFLDEDLTTKDQVDQWLKFYDMNAPLNCFSVVLTDDINKGFRLEHSHFFSEHGQAGHYHFDTTPKDVRYRGYFLVCTEAILIDP---------- +> +-------------------------------------YLSKAPFNMTSRGFGNGLRIAEIGGPSNLFPKLHKEKAFDLNEVCATCDAPHAAVFGPGAGPWPVVGVNCEMVADANLSQHNLYIQTATKIAYIEENSSNKYQTKI-ID--STKFSLMANLAVSENDPSEVVHFKCSIRTGQLNLPETIRRAIAEHYTDKPVSLAGLFILHEGEAKLHVMP-DFPSCPFNNTDEVI-------------------------------------------------------------------------------- +> +--VADLYDPGLEALGLGLKQNLQSEFEHVDVCVCSCPDLRQDPFGLPFTGIGGDPRLVDIGGVPNLLPRFH-DLSFAIADIVRCTRLADQAVLGASAADANFVGCNGELMPAEAIMNYPTSADASSFSATIK--HDACHLQPY--P--HGRIGFLGNLLISRGSASRVLKITASGHRTASSFMIAVRTAVAAAFPNRAVGLGGVFTMQSGTVRAHVMP-DFKTTVMEDGDEVNEWLRFFRFESEATFLTTTLTQDPCLNLRLEHTHFFNARGIGGHYHHDSAEKYAKYVAYLVPARKIFRIENA--------- +> +---------------------------------------------------------------------------------------------------------NAEMMPNLYVKK-DKTILQETRITRTHDEDGSYSTIKLPET--ETRNALLGNLFISDGKPGEVLRIDCRERIGEKNFVTCMRETLADTWPELAIGLGGVFNIGEGRAKFHVMP-DFSPCPINTNEDVNQWLKFYEVSSPLTVLSVFVSRDPDLDLRVEHSHGWGDGKQGGHYHYDTTP------------------------------ +> +----------------------------------------------------------------------------------------AQLVMGPGAGSSKILKVNSELIANVNLKSK----SLLSKYAIVNEKG-DYVMGDY--K--STEFGILAKLLVSEGNTGKVLEVKASNRTGNLNFVTCMRKSLEENIKDQSVGLGGVFNIKTGKIKAHVMP-DFPSCDLLNQKQVDDWLKFYEMKAPLTCHSIFINNDLNKGLRLEHTHFYSDHGDGGHYHDD--------------------------------- +> +---------------------------------------------------------------------------------------------------------------------------VASKITTLAENK-SVPFETKTIN--STKFTLTGNFIVTAEGPAEVVHIKCSERTGKLCFPDTLRESLEQRYGKECVVLGGLFRLLRGKARVHIAP-EFPEKPWKSMDEVEHWYQPFVVSAPLLCASVMHSYDPGFKLRMQHTHCISDHNDAGHFENDATPEEAEYEGWFTAAEKMYRIDE---------- +> +-RTAPLLVPPLEEVRGALAEALSEDYREAAVDVVDCPDLKT--WRLCQSGLGGKGTLVDVGGEPFNHTLYNQKVRFDISKVCASFGRGKGAVLGAGACCAEVIGHWGELTVTAALAN----GANGSVSARVLEDK-SCCAEAY--K--SLLHGGLMNLYVTEGLPGKVLRVHAKARTGERSLTQTLRRGLQASFPQAAVGLGGAFKVVQGKVKSHVQP-DLCACSVEELKCTKPFLQFYEGGPDLVCVTSLWSKDPHMRASGEHTHFFSLKSEAGHYHGDDPTSEIEYEGYFTCAGEIARVR----------- +> +-KSKQLWQPDLADLASALQQELDKHFNHAKVRVVDCPDLTK--WGCAACGLGGNPVLVEGGGEPFNHDHYNKEVHFKLDRMAEQVGHGPGYIQGAGACAAQLRGHLGELVPCLTIGK-----QNMTKVARVESKSRAAIVEE---D-NTLMCGGISNLYMCKGERGKVVEVEASGRKGEASLTQVLKTGLGNLPGGKQVGLGGVFRMETGTAKAHVNP-DMEVLDPTQMKCVKDFLQFYDFPAPLLCFTCLWTDEVSLNLRGEHTHFWREPEAGGHYHGDTSPEKVSYRGYFAPAGTIFRL------------ +> +----------------------------------------------------------------------------------------------------------------------------------------SYELVALPES--ETKMSLLGNLFLSNGEGGKVIKVNCKKRSGSDNFVSCMRKCLEKEFPTESLGLGGVFCAKKGQLKIHVMP-EFSTKPLELDSDVENWLNFYTMDSNFTCFSVFVSRDPGLDLRVEHTHGLNEKCQGGHYHYDITPEVIEYTGYFNLAEY---------------- +> +---ITRHQLSLHELAEVLESALPKNYVTSSTTVVDCPNLPQSPFSLACEGLSGCQVIADIGVQPSLFPQPRLDEQYSLIVCVRLMGLDPEAVVGAGAGPIHVHGTNSEIAPNLSWQGGFGNVDNLTRAARLVTTLAGSRTRICCPYSDSTECLLMMSLYGSMGLPGPVLKVTARGQRGENSFTEFMRSALQDIYA---------------QTQFHVMP-SLPHSPFKSQAALDGSLSYYDISAPMVCLLVFHSADPQLGVRMEHTQ----------------------------------------------- +> +-----------------------------DVVSVVCP-LTR--FTFPVXXICGKTRIAEVGGVPYLIPLVNKKKVYDLNIIAKEINLPGAFILGAGAGPFQTLGFNSEFMPVIQTESEHNPPVNGSYFAHINPADGGCLLLSHSQKHHDFGCALLANLFASEGQPGKVIEVKAKRRTGQLNFVTCMRQTLEKQYGDKPVGMGGTFIVQKGKVKAHIM------------------------------------------------------------------------------------------------ +> +-----------------------ENFAEATVTVEECPDLRQAPWGLAGPGLGGETRVMDIGGVPYLMPLVQKEKLYEMKDYPKMTGLKEGLVIGAGAGPWPFLNRNAEMMPNFFVKE-DGSVLQETRIARTHDEDDSFSTIKLPKE--ETRNSVLGNLFISSGEPGPVLKIRCKGRTGPKNLVTCMREILAEAWPSETLGLGGIFRIVSGEVNT--------------------------------------------------------------------------------------------------- +> +---------------------------------------------------------------------------------------------------------------------------------------------------GAARCGLLANLFLCEGKAGDVLKVVAKGRVGAASVVTIMRKAVAEAFGG-EVGLGGVLRLVGGKAKLHIMP-DFCAGGLHSDEDVDKWLKFYEVEAPLVLMATMVTGDMGLDLRVEHTHGYG-ESMGGHYHGDLGGEEVEYEGWFNVAERMVRVDRPVVTHQIGRD +> +--SAELFVPPLDELAAAFTSGLARHFATVEVDVVDCPDLSTPEWDLARPGLCGRPRLVDLGGVPNLLHPAGNGTRFDGADVASKVGLPGAFLLGAGAASPRLVGANAELMINEVS--RW----SEPVAQTLLGEGAPSCCSRC-AT--GAEVGLLANLLACEGAPGKVVRVRVAQRTGSTNLVSAMRAALLEHFGDKRIGMGGAFRVVSGRVKAHVMP-DFPCVHMSEAGDVARWLRFFEMGPSLTCLST--------------------------------------------------------------- +> +-----------------------------------------------------------------------------------------------------------------------DHVEXGTHVHMTMSDDAECFHKSLPDD--EMRFSMMANFFSSNGFKGEVLKIVCEVRKGPLSFSTCIREALAKHFGDDIIALGGVILIENGKVKIHVIKPSLAKIPIKSEKELGNWLHFIELSPPSVGVGCIVSHDPGLNLRLQHFHLYTDRNEGGHYHNDTEPNTIKYTGYFGVSKQFIKID----------- +> +---EPLFVPEMEEVRKALITSLSEDYRESSVEVVDCPDLTT--WKLCQKGLGGKGTLVDVGGEPFNHAFYNKKVKFDISKVCASFNQEKGAVLGAGACCADVIGHWGELTVTANLAD----GSNGSVSARVLEDK-KCCAEKY--D--SLLHGGLMNLHVTEGLPGKVLRVRAKARVGERSLAQTLRRGLQVFP--KAVGLGGTFKVLQGKVKSHVNP-DQCALNYYSVEELKPFLQFYEGGPDLVCISSLWTKDPAMHLRGEHTHFFSLKSEAGHYHGDDPTAEIEYEGYFVVANELARV------------ +> +-QKSPLLVPELKELAAVFETILKEIYSEVSVKVVDTPDFTRAPWNLAAVGIGAKPDLINIGGVDNFKNPKNNYKKFNFKKLGETIGQPYAFISGSAGASSDYVGDNAELIANLNLDS----RLNKSKYAQVVKNSNNPGYKLY--DHNTLEFGLLGNFFASDGKAGKALEVKVSKRKIEQNFVTGLRLGLLKKYGDKPVGIAGIFTIKNTQIESHIMS-GFPTTELLTSDDTKKYLTIFNFDAPATVTATIISSDPKLKL----------------------------------------------------- +> +-ETISLFQPDLSQLINVLTDGLQYHFEIVEVKCIKCPNLTDKPFNLVGNGLSGNEAIIGCFSTDDELRRATETATWDLKDFAMHF-CNKLFFIGGGYAGMPNLPFNGTLVMNATYSA-PQQINNESGIVFKDTNSNRIRMETLNDP-DYMICSMNGNFFMSEGRDGTVLEVRVMKRRKKGDIINLMMNSLMAAFNDCSIGLGGILIMKKGSVTHQVLPDNVEMSTLKTPFVLSNHIEYHNSQPFLISLGTIVAVSTAYQNRLHKFYSFSNNENGGQFFNDISSNDIEYIGYFNAAKELFNI------------ +> +--VIENHVPSLDELKEVFIKSLTENFETVTVDITTCPDLSKPPFNQTSSGFGENLRIAEVGGPGNLFPGFHIDHQFDITTIGKVCELPEASVFGPGAGPWPVVGQNSEMVADVNLKT----GRSATRIAEIKPGNGNKKYLQRSID--QPKFSLMANLALSNAKSASVVHFKVSVRKGEKNLTLCIRDGLQKHFGDK-------------------------------------------------------------------------------------------------------------------- +> +VEKFPFHVPRLEELAGVLQNGLKNNFADVQVSVVDCPDLSKEPYTFPVKGICGKPRIAEVGGVPYLMPLVNREKVYDMNTVAKQIDLPGAFILGAGAAPFQTLGINAEFMPIVQTESDHKPAVNGSYFAQINPADGGYLLEKYSGKYNDFGFALLANLFASEGQPGK-------------------------------------------------------------------------------------------------------------------------------------------------- +> +-ERFAFHVPSLEELAGVLQKGLKENFADAQVSVVDCPDLTQEPFKFPAKGICGKPRIADVGGVPYLIPVAKTEKIYDLNAVAKDIELPGAFFLGAGAASSRITGGNAELIPIVQTKSEKKPAVNGSYFAHINPADKGCLLEKYSSKYTDCEFGLLANLYASEGQPGK-------------------------------------------------------------------------------------------------------------------------------------------------- +> +-----------------------------------CPNLKN--WGCPAEGLSGNQKIIDVGGEPYMHDKRYIGAEFNYEEIAKLIGSEKSYALGAGSGAMSCSGHCGELIIDDNLITK----ENKSIIAKVGKNK-ECITEKY--N--GRKHGGLGNIFYSDGKKDKVLKINIKGRSGKGSLPQAIRAALINQLNNNHIALGGIFRILKGQIRAHVQP-DYEDIKHEYYKCTKDFLQFYEVGPNLQCYSVLWTGDPKLNLREEHTHFYDNKSCSGHYHFDVTPDEIQYEGYFNTADTVYRVNNIYKE------ +> +----------------------------------------------------------------------------------------PSYLIGPGAGSAQIHGVNCELMCNCKIDGRSESLQFRHKVALINWKN-KFILNPC--F--ASECGPLANIFASTGAEQQVIKIDVKSRKGPMDFVHCLRSALMQYCEEQAIGMGGVFQILSGSIKAHIMP-DFCNEQLAVEGDVQRWLRFYEAKKALTALSYFVTHDPQLGLRFEHSHFFEEGGCGGHYHYDTTPETIHYVGYYVVAKLLYRVSQPAA------- +> +---------------------LLKNFAEVKVEIVASPDFTKQPFNLAAPGFGGRPTLVEVGGTSNYNTQIQKQKLFDIKTIVENLNYTDAFVTGAASGPWPFLQKDCDVAINVVLNK--QKSATSSYLITLDKNRGKIVCQALPLS--ETRFAVEGNLFLSEGKSGKVLKVYAKKRIGEYSFIASLRKSITDHFGKKLVGIGGVFVLKTGKTG-ELFP-NFLEEP---------------------------------------------------------------------------------------- +> +--------------------------------------------------------------------------------------------------------------------------------------------------------APVANVFCSKGETGKVLRVYVKKRIGQADFIACVQQVLKDKYGNRPVSLGGSFKMMSGKAKVHVMS-DFTQNPIQKQEFIKEWLKYIEAEAPFTFMTVCTSVSPGLDMRLTHTHGHSTPMVGGHYHYDLSPDEIEYEGFFGVAESIVRVDQVSQTPDF--- +> +---------QVGQVAEALQKGLKSHYTSATVTLDSYPAVSKWTGGKIQRG-CANVSLYQIGGGQNLFDPSRHGVAFDAEDILKITERKGKFFFGPGAVDSRVVKTNAELIAFWETEN-AKVTHIRSKSAKITDVSKSFQLVE--YA--STAFGGLAAFTHCQDKNETAIRIKVSGRITKLDFMSSLRQILLDAFPDKSMGIAGIFTMPSGTFNAHIMP-EFSSANLT-LAQFTDRLQFFEFEGEAVFLGHGVTNDPKFHLTPTHVHFWNTSMNGGHYHYDVTPDQVEYEGYFFVASKLFRIADP--------- +> +-----LDQPDLEELRDLLDQKLRGSFRDFRVNVVRCPDLTAHPYSLASQGLCGHPEVIQVGNFEHMHDPHIEILPWHISDLIDNC-CEGRFIIGEGLLR--DIFTTKELMMNMTYAR-KRVLDNNSYGISVNDK--RIVSKRLPDS-YPAVFDLYGNFLVCGGLQKNVLEVRAKKIDSDVNILQLIRNALCQRYHNSNVGLTGVLLINKGSIEAAVVPPAFMPTSLRRINETEDFSIRYNIPAPLAVHTTMFNFNELPDDEMYVVNEYSNERMGGSYRKDITPHAMEFVGYFNVLNKLHRVH----------- +> +--HLALYTPDLKDVAEAVTKGLQENFESVEVKIHDCPKLNE--FNLPVHGICGNARIAEVGGVPYLYTKKHQKTEFSINNICTAAGIKQGLLFGTATPDASVENKNGEVVVNLHLNNSKEENKNDNEADSGNDDQKNEHLIITPY--TAKDIGCKANLFICNGKNEPVLYVKVSKRTGKLDVIEALREALKMVKGTTQIGVGGVLRVRKGKVKVSVSNPEYVELDYTKTENIEKTRQVHEIGPDLVMFTTFLTGDPKYHLTLASTGCYYNVNQGGIFVES-ASNEVEYEGYFVLAKYVYRVEDAYY------- +> +--HCKLYQPKWKEIQKAVSNGLQKNFKNASVEVVTCPDLKK-KWGVCDKGLCGNTRLVDIGGVPYLFHPSYQRKTFEVPDIVKTCNRNTPLVFGSCAGSYSVVGKNNELILNTSVPG-----GKNSKYAKITDNNKNDKNEK----KPSEQIGCLGNLFLCDGKIGQVLHIKARVRTGKDNFVTCIRESLKDIKGENQIGLGGVIKIHKGKIK---------------------------------------------------------------------------------------------------- +> +---KNIPPPSLDEIRMVLETGLRKNYEEAVVEIVDCPDLSKEPFKLAAKGICGGTCLADVGGVPYLCPGPARERVYNLDHTATQVHAPGGLVIGAGAASKHDVGVNAELIMNIRTSGGEAERKNETHCARVDPADKKALLLHYEKDLKSADFTLLGNLFISKGERGKVLKVTAKKR----------------------------------------------------------------------------------------------------------------------------------------- +> +----------------ILTHALSMNFSEVAVECIDCPDLRQ--YRLVAPGLCGNPAILEIGSLSYLFPQARLDKKYYFKNILRQLNLTSQFIIGAGNHSYPPNYDHSELYANFMLSRGSMGVQNASNALWFGGKEEELKWRYVCET--NPMCAIQGNFFVSQGEPGNIFRINAVNRTGPLDFVSSIQMSLKRMRQPHLIGLGGIFTTSDDNAILHGIPGKRNATEFYTMNQVQQWLKYKTITEPIIAVGTIMSE----------------------------------------------------------- +> +--HLALYTPDLKQVVNEVTAGLQANFADVHVEIHDCPKLNA--FNTEVHGICGNTRIAEVGGAPYLFSANHQKQSFSVTDICRAAGVQKGLVFGAATPDPSVENKNGAVVVNLHL-NNE----EQKQQEQQQQQQQDKDVSLVTQQYTAQDIGCSANLFICDGNDDAVLYVKVSKRTGALSIVEALRTALKNVKGTTQIGVGGIIRVNKGKVKAYVSNADYVELDHNNQAAVDDTRQMFEIGPKLVIYTTFLTDDPKYHLALQSAACYHDVDEGGVFVESATDDEIEYEAYFTLAKYVYRVEDA--------- +> +--EKSCHVPELGFFISALRTKLKDYFEEVTVQCVDCPDLTQPPYRFVAPGLCGNTGQLITGKFATMYPLPQSEKIYNFKKILRKIKRNKNFLLGSSLCSMAPQEVMCTVFINLLFSPNRKTREKLSLVYALDPIEQNYTFSSCIINNPDPECVMCGMCFISEGQPGQVLKIHVKKCINKLGFTAALHQSLREIKGNSPLGLGGTFVMSGGNVTTAIMP-KFPPNPLDNVEIIEANFRKNVATESLVVAGAVTSEYN-P---YLTFCTFNQYEACGMFDEKNSKDVTEYLGYFSLIENIYE------------- +> +--------------------ALASNFAQAEVTVVDCPNLTEAPFKLAGAGLGGKSAIADVGGVNNMEYVANNNKHFNIDKICESVEIPGGFVLGAAATKCSASKDNSELMPCVHVGG----AKNNSKEAYVDKATNQAVLADY--P--HHDVSSLANLLICEGSSDPVIKVRAAIRTGELNFVTCMRKALTEHYPEKQIGMAGSFIIEKGIFKSHIMP----------------------------------------------------------------------------------------------- +> +-AELPLHCPPLEELADVFRAAAATNFQHVDVDVVDCPDLTLEPFKLVGEGLNGNPTLVDIGGVQYMAPMPQHSKVYNLIRVCEDIGMPTAFVIGSGAASFKHIGYNCELIANVNLAN----GKIASRTIRVNADS--VGVCEL-YE--SVEFAMFGNFLACDGRPGKVL------------------------------------------------------------------------------------------------------------------------------------------------ +> +---YGVHEVSMEEVAKILQNGLKDCFKEVRVNVANCPDLTKAPFRLSLAGLSGQNVVCDVGSMKYLLPVADKSKKYSFDKVAELSKVIQGQLLGAGAGPFFTHNKNCEMAANVNFSD-SKVISNSTLHGVYDETT--NKPEVIRAT--DNNFALLAHLLSTEGLQGSV------------------------------------------------------------------------------------------------------------------------------------------------- +> +-------------------------------------------WGLAAQGLSGSPRIMDIGGVPYLIPTVQRDKLYDMKDYPALADLKEGLVIGAAAGPWPFINRNAEMMPNLFVNE-DKSVVQQTHITRTHDADGSYETLKLPET--ETRNAVLGNLFICEGKPGPVLKVHCKGRTGEKNFVSCMRETLQSHYGDKELVLLCFF------------------------------------------------------------------------------------------------------------ +> +---LALYTPELKDIVDDIQKGLETNYKNVEVKVLDCPDLNTEFLQLADSGICGSTRIADVGGLPYLYNKSFRDKDWEVHNIIETCGMKQDFVFGSANADINISATGGEIVVNEKVGVNAEKKDNNDDDSKND-KSDRPKVDTY----VSSSLGCKANLFICDGKNEAVLYIKASVKTGELNITNCIREALSKVKGATQIGMGGIMKVNAGKVKAYIMP-EYVDIDYKDNDAIAKSRKTVEIGPNLLMFTNFITADPKYHFSLESTICQGDVHDAGVFIESATNDTIEYEGYFTLAKYIYRVEDAYHN------ +> +--NAALFIPPLEELVSLFQAALAKNFAEVEVKVAEVPDLTQAPWHLAGKGLCGHCRLLDIGGEYNLFYAKNHHATFDFDECAKLAELPNAFMIGPGAGLKRIVGINCELMANVNVGE----RNYSSYISRLTEDEK--PLQ-LLYP--EKELGILCNLLASAGEPGKAVYFRAAKRTGAANVVSCIRE----------------------------------------------------------------------------------------------------------------------------- +> +-KTYELEVPDLSELCSVMKESLQGHFNDLMVNVVECPNLRRHPYNFAASGLCGGQEVIEFGNYRHLYNLTKSPKSWNLQNLIQKYYEGDSFIIGESMLC---GPPNKECIVNATYTQWGYTFNDKSYCTFLNEEE-QIVSELVANSRSRPKTYLYGSVFVCSGERKPVLEIVAKGSFNSMNILNLMEDALHTRYFSAKVGLSGVLLINSGMIEAAVMLRTFTQTPLTEFSTINELKTTYNVSAPVTIYNTMFNFDRILD-EK-------ESLMGGRYVRNITP-YIEYKGYFTVVKKLHRVDAE--------- +> +-----------------LHSGLLNSFDEVSVEVTECPNLKSQPYLLAAEGLCGSPRAIDIGGVPYLIPSPCMEKIYDLSKAPSWAEVDTSLMVGAGAGPSHVVGKLSEMIVNISFDS-SSQATNQSRICKIDDESGKHVVQRV---ENSMDCCHLTNLFVSEGKRGKVIEVRASRRRT--------------------------------------------------------------------------------------------------------------------------------------- +> +----------------------------------------------------------------------------------QASRLVQGMIIGGGLGPFQTYNRPCEVAADITFTT-RGLESNHSLVGFGDVESESSKFCRA--T--NSYIASMGQFFVTEAKPGKVIQIEAKDRRGGQNIFDMIQRALYEEYNELPMGVGGVFCLQNSSAKVSLLN-EVPSETYHTFPCVRKYKTSFSIEGPIIGAGTIVSHDPTTGYMMKSFYCWNARTLMGQFEEDDDPANACFQIYLTVATQIYRHDKP--------- +> +----------------------------------------------------------------------------------QASKQIQGMIVGGGLGPFQTYNRPCEVAADITFTS-RGLESNNSLVGFADKEEEEPEFRSA--S--NSYIATMGQFFVTEAKPGRVIQIEAKGRNGGQNIFDMIQSALYEKYKELPMGVGGVFFLNDSSAQVSLLN-AIPAETYHTYPCVRRYKTPFSIDGPIVGAGTIISHDPTAGYMMKSFYCWNARTLMGQFEQDNNPVNAHYQIYLTVATQIYRHDRP--------- +> +---------SLDEICKALQKGLSNNFKEVTVSVVDCPNLKD--WDCPAEGMSGNQKITDVGGEPYMHDKKYIGAEFNFKEVAKLIGSEQSYAFGAGSGAMSCLGHCGELIINDNFISN----DSKSVVAMVGKN-KECIAKDY--S--ASKHGGLGNIFYTDGKKGKVIKILIKGRSGEGSLTQAMRAALLENLDNDHLGLAGVFRVLKGKIKSHVQP-DYEDIDPKQMKCVKDFLQF--------------------------------------------------------------------------- +> +------------------------------------------------------------------------------------------AGLGPFAASKCSVGCNAEGICNYSLSR-----GNKSRYAKIADSN-DAKLLSCFRDLESKICGPLGNFFVTDGRNGKVIKIVAKSRVSGFSISQAIRKAFCVALGSTPIGFGGVILVRNGKVKGHVMQ-DFVDYEFRSQKTVDDWLRFFPMGDQLIMHSVLVCNETKEEWRVEHTHFYGIENEGGHYHGDISEGDIEYECYFAPASKLVRMNQT--------- +> +---IDLFIPDKIKLATVVKNELSTSFGEVTAEWVDCPDLTQEPFNLAAPGLGGDATLLDIGGTANIFPFRQ-LKIYDFKNILNQLNRSQNFIIGGGLSTQPMTLNYGHLIMNGTVANEIIAVSNKSRFAFRNRFEEQFALEILNNP--FSKCHMYGNFFVSQGLREQVLKVEAKERT-GHDFIEAIQRGISRIFPSKL------------------------------------------------------------------------------------------------------------------- +> +----------LNELISTLSEGLAATFEEVEVVEVTCPNLSLSPWNLASNGITGDVTLADIGGPDNIHYTENNGTVFNLQEISKIIKKEGYFVAGPGAASTSICGINGELVANLNLSN----RNYKSHCTLIDNNN-SYITKEY--K--SEEIGVLANLFLCKGEQDKVIKIKCKKRIGKDNFVTSI------------------------------------------------------------------------------------------------------------------------------- +> +-EEKSLHVPELDEIVQVLQSALSRNFQEVTVEIVDCPNLTAEPYSLVCEGLNGSLTLMELGGFATLLPLEDKGKVYDIVETSRKIMKGKDAIIGTGAGPVSLEKSNCEIILNMNIPL-KGNLENKSIAIRINEDD-EISLDPI-ND--QQIFSYLVNIFLCEGKSGKV------------------------------------------------------------------------------------------------------------------------------------------------- +> +-------------------------------------------------------------------------------QICETVSLPGGFVIGAAATKCSASKDNSELIPCVCIGK-----NNLSKEAYVDKKTDTPVLADY--N--STEISSLANLMISSGTTDVVLKIQAKVRTGELNFVTCLRKTLAEHFPDKQIGIGGAFVISKGNIKSHIMP-SFP--PRDAFGEPEIWLKYYSVSAPLTALSVFVSNDKHNDLRLEHTHFWTHD------------------------------------------ +> +---------------------------------------------------------------------------------------------------------NGELMSSNCVTK-----RNTTHFSLVNSK-GSCHCAIY--P--WMEQGPLSNMFVSDGKNTDVVHIEVETRIGNDNLISCIRKGLTEHFQKKQLGLGGVFFLEKGKVQAHVMS-DFASTLIDGPEVINDWLRYYQVGPNLVFLTTMITGDPDMHLRLEHTHFFSKPITGGHYHHDTTPA----------------------------- +> +------------------------------VSVSKCPDLTQPPFSLAAIGLSGHVALADVGGQLNMHYKANHNKHFDIKNISQEI-NGLPFFIGAGATKPSVSRDNSELMPNLNISSN----VYLSKEAYVGQDGSG-HLVDY--P--STEFSGLANFFVSEGKPGTVLKIEACGRTGMQNIVTCMRQAILDHYGENQIGLGGVLLVKKGK------------------------------------------------------------------------------------------------------ +> +----------------------------------------------------------------------------------------------------------------------------RSKVGIVEGDHDQRGIKSID--YEGHEVSSLCQLFVSSGEVCPAIRVHLRGRKEAGDLLAEMQEGLARAFA-EPISLGGVFTMPNGTAKCHVMS-DFTPEPICSQQYIEKWLRYFY-EEKMTFVAVCTSKDFALDMRMLHAHGVTDGRWCGHYHHDTTPETVEYEGFFLPAVKYVRVDQCSHTPDFAKD +> +--------------------------------------------------------------------------------------------------------------------------GTETKKAKKKKTGATSKTAAL-SSYDSCEMGFLANLMASEGQQGPVVKVTAARRKSETSLTRCIRKAMAEHAGESKVGMGGVFKVKAGQVRTHVMA-DTGGRIFTEASQVQEYLDLFTMGPGLVAASVFLSKQPETKARLEHTHLFSEMKTGGHYHGDVTPAEVEYEGYFALCRELVMIDK---------- +> +---------------------MAKEFREVKVDIAACPCLTRQPYNLAGVGINGNSSLMEIGGPENVVSHNDYGLTWKVQELLSSA-YFDSFIFGNGYAAKPYMLYNGHLIVNAMYRA-PSNFTNASRIVFADASNRQRRIEMLTDP-DQMLCSYMGSFFISDGRPGLVLRVRAKGQTSIFDIITIMQNSLYEHFGNK-------------------------------------------------------------------------------------------------------------------- +> +-----------------------------------------------------------------------------------------------------------------------------SQLATVRRDEDRPSLSSY----NSSTMGFLANVMACRGYQGDVVEVRASVRKSSESLTERIRLGVARAYDAPDKGLGGVFKVTKGKVKVHVMA-DTAGRVFTHSSQVQDYLKMFTMGPALTCATVMTTRQPAGKVRLEHTHLFNAGTEGGHYHGDVTPQDIDYVAYLVPCEALLLVDK---------- +> +---LELYTPELKDIINDIQKGLETNYKNVEVKLLDCPDLNTEFLNLAATGICGSTRIADVGGLPYLYNKAFREKDWEIHNIIETCGMKQEFVFGSANADINMSDTGGEVIINEKVGVKKKEIEASMDENKENNKKSETPQVKV---YYSSSVGNKANLFLCDGKNGPVIYIKVSVRTGGLNITNAIRESLKKVKGAKQIGMGGIMRVNNGKVNAYIMP-EYVDIDYKDNDAISKSRKTVEIGPNLLMFTNFITDDPKYHFALESTICQGMEEH---------------------------------------- +> +-DTVPLAKISQNQLMESLAQALTPSFEEVQVDIVETN---FDAFGWVKPGFGNICHLVDVGKLENLNVAEFRKEQFEFNDIIENYTKIPQFFVGAAAANFFAYNKNGELVLNCDDVT----CSSLESLVSSDGQ-----QTIVPNG--YRSTGFIGNLVASDGTPSNMTRILARNRLTGSDFGQILTDALSP---FKDLAFGGIINLVQGSFTFHAMP-DTFPAGNMTDPEIQQWLHFFTENTDYTCASRFVADPSLLDAASAHVHCFRDGTFVGHYRYDNSPQDVVYEAFLMPCDTL--------------- +> +-----------------------------------------------------------------------------------------------GGGPLKKLGHNSEAIINFRTGEIGKAIVCHNYVASWQKDG-TRECKVV--E--KPQISYIGDFYASQGLPGRVMQVKLKQRKSEADILALLRDLLIERFGTRSIGMGGVILQKRGKARLHILRPELGEGPL----EMSQLCTQFEATGPLVGLCMLMTNDCGIKMNQTHMHMFNNEGTGGHYEEEVSADSVEYEAYFSFGTRAVHFDAPK-------- +> +-KQHSLFVPTLDDLSIGIKNSLEKNYKNVEVCVQSCPDLTY--LGVASTGICGRTCLLDIGGVPFLLDPEWQDVYFDLKKLLEAIERPMGNIIGAAASWKGRVGVNGELMASSCSIT----QRNTTHFSLVDNKG-SCHCAIY--P--WMEQGPLSNLFVSDGKNRDIIFVEVETRIGNDNLISCIRKGLLEYFEEKQIGIGGIFFL---------------------------------------------------------------------------------------------------------- +> +IEKASLYVPELDQLAAMLKESLRGNFETVETKVVECPDLTK--WGLAAPGICGNQRIIDIGGVPNLLPKYHGTAFFSIPQIAEDVGMKGGYVYGAGAASSKVVGVNAELMPSEHISEK----CRCSRYSKVLEDG-SHTMEKY--N--SNEFGLLANLIACDGKKGNA------------------------------------------------------------------------------------------------------------------------------------------------- +> +---------------------------------------------------------------------------------------------------------------------------NRSLIGFYSKECGSPTSERA--S--NTLLSSVGQIFITEAMPGKVIEIVAHKRIGGPSIFDLIQASLYDKFSDLPMALGCVFYLQNSGVQASVLC-ELPQEPYHTFPCLKKYQASFTIDGPIIGVGTVLSHDPKKGFSMSTFNCWNARLLTGQFENDVCPEKATYTVYLTPAKKLYRQDKPV-------- +> +--------------------------------------------------------------------------------------------------------------------------------------------------YPSEEVGAASNLFICDGNDEPVLYIKVSVRKGKLNIINTIREALKSVKGAAQIGVGGIIKVTKGKVKAYIAP-EFVELDYNDTDTLEKSRKYFEFGPNLIMFTTFLTDDPKLHLTLEATTCYTNSNEGGVYVESTDDDNIQYEGYFNLAKYIYRVEDA--------- +> +---------------------------------------------------------------------------FELRKILNVVGMPKGTALGAAAAWNGRIGVNGELMPYASVNN----GTNTSHFSIVDRDG-NCECNHYPYL----EQGPLSNMFLCDGIQGDVIKVEVEVRTGEENLVSCIRKGLIETFNGRQIGIGGVFIVKKGKVKMHVMP-DFYPSMVDGSEQVKEWLKYYEVGPN--------------------------------------------------------------------- +> +----------------------------------DVPDLTQ--YGWVTEGLGKSPVLLDIGSGEYLLTASCHNSTYNITSTTQSIPELNGSFYGASALYEPVIGHNGEAVNNYKFGV-----GSSSIGAIVSDDGSSIDVVQLPT----DSIGPFGSLYFTQGESVDAIHVHVKTLLASERFDYAMQRALTDAKDLGAVGLAGVIRLLQGEITFHVMK-DFVDYDLTS-ADWSWWDTFYPMRSTIECSTRLLSNDTMFTSIGAHTHCYKDYSVVGHYENDTLPPAHEFEAWLVPSPLLVRVAKPSNGN----- +> +--------------------------------------------------------------------------DWEIHNIIETCGMKQEFVFGSANADVDISATGGEVIVNEKVGVKE---------------------------QVSSSVGCRANLFLCDGKNEPVIYIKASVRTGQLSVTNCIREALKKIKGATQIGMGGILRVNAGKVKAYIMP-EYVNIDYKDNDAIAKSRKTVEIGPNLIMYSNFLTDDPKYHFTLESTICQGMQHDAGVFVEASTNDTIEYEGYFTLAKYVYRIEDAYHN------ +> +--SANLFVPTLEAAKDALASALKEDYKTSSVEIVDCPDLKE--WKLCQSGLGGQSVITDIGGEPFNHPKYNQKVRFSMPKVAEACECSACPALGAGACFAGAIGHWGELTVSADFSK----GKHNCIAATVDQETRKCVASKY--D--SEMHGGLMNLHFTDGTPGKVLRVRAKGRVGERSLSQTLRRGLS-------------------------------------------------------------------------------------------------------------------------- +> +-RTVPLFVPPLEEARDALRTALAEDYRESSVDIVDCPDLRE--WRLAQAGLGGKGTLVDVGGEPFNHDKLNSKVKFDMKKVCSSFGRDKAAILGAGACSAEINGHLGELTVTANLSD----GANNSVSARVLEDK-SCCAEEY--K--SLFHGGLMNLHVTDGSDGKVLRVRAKARVGEQQ------------------------------------------------------------------------------------------------------------------------------------ +> +----------------------------------------------------------------------------------------------------------------------------------EDKKSETPQVKVY----YSSSVGNKANLFLCDGKNGPVIYIKVSVRTGGLNITNAIREALKKVKGAKQIGMGGIMRVNNGKVNAYIMP-EYVDIDYKDNDAISKSRKTVEIGPNLLMFTNFVTDDPKYHFALESTICQGMQHDAGVFIETSTNDTIEYEGYFTLAKYIYRIEDAYHN------ +> +--------------AAVLREDLPTVFKECTVDILEAKSVVSSWTNLSIRGLGGSPKLVDIGGVPNLLEPKGHHLSFDICSVAETCGLSQGLFFGAGAGDARHVGRNSELMPLYLVSEEGTVSHNETRVAFLTPEKGDDCFECTKYS--STRVGFLANLFACKGEPCSLLSVKVSGRTGSQDFISAIHRILK-------------------------------------------------------------------------------------------------------------------------- +> +-----FTEYSLDKISEALQAGLSKNYKFSEVSVVDCPNLRD--WDCPSEGMSGNQKIIDVGGEPYMHDPNFIGAEFDYEQIAKMIGSEKSYALGAGSGAMSCLGHCGELIINENLITN----ESKSIIARVGKEK-ECIAEKY--S--ARKHGGLGNIYYTDGKQGKVIKLKIKVRI---------------------------------------------------------------------------------------------------------------------------------------- +> +------------------------------------------------------VSLYDCGSPKQVEMVEGRTAHVCMDKLMAEREAGNTWLVGAGATG--AGPCNGELIVVASLGSDRDTTRAGIRSVAVYADPLACPVSTR--PYRSLCVGPVANMVAGPPLRAATTCVRLQGRGIKTNLISVLNDVLRRGFARGQVAWAAVTRVTSGSVKAHVMP-PFPDHDLSTPALVNDWLQFYEMPAPLTMYTAAITDDRHEGLRLEHTHFTSDTGAGGHFHHTTTPEHFAYDVVIIFATRLFK------------- +> +---------------------------------------------------------------------------WSVSEIIRDLGLGRVQAFGPGAPGYSNVQQNAELVCKMELCS--GGWECRSKVGIVEGDQDQRGIKAIDYD--GHEVSSLCQLFVSDGEVCPVIRVHLKGRKEKGDLLAEMQEGLARAFP-QPVSLGGVFTMPNGTAKCHVMS-DFTRGPICSQQYIDKWLRYFY-EEKMSFVAVCTSKDFEGDMRMLH------------------------------------------------- +> +----------------------------------------------------------------------------------------------------------------------------------------GVSCKKY---ESADQFGCKANLFICQGNDGEVLYIKVKTRTGKESLIQCLRNALKKVKGDSQIGVGGIVKV-KGKVKAYISP-KWVEIDYNDKDAINKSREEIEIGPDLLLFTNFLTDDPNYHATMESTICQQSPHEGGVFIESAQDDIIEYEGYFILSKYWFRIEDPYHNIDIEN- +> +-------------------------------------------------------------------------------------------------------------------------------------DKDIFKIQHY--P--SNEIGCQGNVFLSEGKDTRLLLIECETRIGDDNFCSAIQKVLQKYVNTR-EGLGGLIQVLNGDINGYLISNN------NEHKK------VNANGSNIIMYSTIISNDVKNKLNTNNCQFINKKNQAGNYVNDTTPKTIKYRGYFNIAKYLYVVGNPNQS------ +> +----------------------------------------------------GKSVITDIGGEPFNHPKYNQKVRFCMPEVAEACGCGGSPALGAGACCAEAIGHWGELTVSAHFGE----GTNASVAATVDHETRKCIASKY--D--SNLHGGIMNLHFTDGTPGKVLRVRAKGRVGDRSLSQTLRRGLSTFP--NAVGLGGAFKVLSGKVKAHSQP-DLCLCPYYNKEEMKPFLQFYEG------------------------------------------------------------------------ +> +-------------------------------------------------------KLVEGGGEPFNHDTYNREVAFQLERMARLAGHQAGFLFGAAAGVKQLGGHIGELIPCLVLQG-----ENKTKAVRVDSETRSSIVSA--D--TSGLCGGISNLYLSQGKAGKVLKVVVSGRTGPISLTQSIRAGLRNIPEHCQVGMGGVFRMKSGLVKAHVNP-DFEVL----------------------------------------------------------------------------------------- +> +-TRFPLSVPQGQALSRAIENGLKQVYKQVKVRLVPTNDLSAQPWNLAASNLGTNGIFCQLGGAKYVEYKQGHSVRFDMSSVLDQLHIKNNLVIGPGAGDLTHLSVNGELIFNMTFDQY-NKVQVQRSYSSIVTDDNQAYQAEYQ----PKTCGPFQHVMISSVKSSILIEIDVQQRL---------------------------------------------------------------------------------------------------------------------------------------- +> +------------------------LYDTFSVSVVDSPK------DLPGIGWLSDGMLLDVGGVPNMDNVERHDVQFDLDDLVENT--SSAFASGALAAAPCVAGCNAEGIMCCELVAGERKSRSASKYTKITSER-PWSDA-----TPLRKLGCLGNFFLQKMHRSSVLKVHARRRLKGHSFTQWLRDAFVEV-GQRLLGFGGVVFVKSGFVQGHVMP-DFLPHKSENATMCNDWLRFFNGPGNCVMFTTMVSKEVELHLRPEHTHFFGVENQGGHYHGDVD------------------------------- \ No newline at end of file diff --git a/esm/source/examples/data/5ahw_1_A.a3m b/esm/source/examples/data/5ahw_1_A.a3m new file mode 100644 index 0000000000000000000000000000000000000000..dbecfbbc8d45c385d2805e74118755269e522312 --- /dev/null +++ b/esm/source/examples/data/5ahw_1_A.a3m @@ -0,0 +1,2048 @@ +> +SAYQTVVVGTDGSDSSLRAVDRAGQIAAASNAKLIIATAYFPAPIYAILREANDRAKAAGATDIEERPVVGAPVDALVELADEVKADLLVVGNVGLSTIAGRLLGSVPANVARRSKTDVLIVHTS +> +PSYRSIIVGIDGTPRSLRTVETAARLARDAHATLTVTCAYPELAVDELLKDAAAHVDDQGSEPAVQYAVRGGPAEALLSIANHVSADLIVVGSGDFASPFGRFLRAFPAEIARRAHSDVLIIKSA +> +TAYHTILVDTDGSDRSYRVIDHAAELARASHARLLILCARHDIPTDTILRTARHHATAHGATDITTHILAPPTLHALLHLAATTGTDLIVTGHPHRHPLLARWLPSLPIELARHAHCDILIVHAP +> +FSYSSIAVGTDGSATSMAAVRAAASLARVYDASLTIICAHYSAGAQEILQRAREIAEAEQAKDIRTVSRGGQPAAVLIESVSEYDVDLLVVGNKGMRSLAGRVFGNVPGSVAKKAPVDVMLVDTQ +> +ASYQSIAVGTDGTDTAEVAVRKAAGLARDTGAKLIIVSAWHGQNAQEYVESAAKIAEEEKAPDVETFTVRNPAANALVDVVKERGVELIVIGSQGVHSLAGRVFGSVAMEVLKRSDVDVMVVNTE +> +-QFNRIVVGYDDTEGSKNALNLAIRLVKENDAQLLVAQVFEEKSVDKAFYNAREAIEPYNI-NAKYDVLEGSPADSICDYAAVEDADLVIVGNSGKGGIKRMFLGSTSAKIAQNAPCPVLIAKDK +> +-MFTSLLVPVDGSAHALKALSIAAQLASPEA-TLHLLYVLPHLEIEAVLQKAQTHLRSRFDGRIETHGRHGDPARIIAYEAEKLGAQVIVIGSRGLSDLSGMIMGSVSHKVSHIATCMVISVHDD +> +-FPTHVLVADDGSPESDRAVDTAAQLVRATGSSLSLVHVS---QGRVLVGRRVAELSAGGIEPEHAEVRLGRIEAAVTDTAMEWGAGLLVVGARGGNPGQRYILGDVSVHLVREARCSVLVVHTE +> +-AGSVIIVGTDFSADAERALRYGFKLARALGGLVELVHVTPELEVEAAREALETLVTETDV-PAQAHVCIGDTCQALLDRADEVGAELIVVGRQGAGALGRFLLGSLTDKLVRRSERAVVVIPPG +> +-GYKNIVVGVDTSPQAYEVFKKAMDVAKTEGSTLHIVSAVPFIERRAILETYVAEAKEYGVETVTLTIESDHSKNLILTELEDFEGALIVIGASTKTPLKRFMIGSTAKYLATHAPCNILIVKSY +> +-ALRSIAVGMDGSPSSERAFEWALDLAKLGGASLTIVGAIPLHTMSELLRRRAESARQAGVHPVASILLEGAAVDELLNFLDEHRPDLMVLGARGVSGARRVLLGSVSEGVLHHAHCSILIVRPP +> +-GYDTVVVGYDGSPDADRALEAAADQVGPS-GTVHVVTASHPEPENARQQVALLRLQGRGV-DCEGHVVVDDPATAIIDVAEREGADLVIVGSRGLGDVRRFLRGSVSARVAVHAPTSVLIVHGT +> +-MYTCIVAGFDGSDAAKKAVEKAAMLAEKLGAKLVIVTVVPTPAVREGLDKLAEDIGRYNV-EIETMVVEGDPAESLLDVAKGKGCSAIVVGRRGR-GLAVKLLGSVTSKLVNIAKGIDVIVVEP +> +--MKKILVGTDTSASADMAVEAAAEIARLADAELLVLHVRPASDPDGYLATMTKR--FPSL-RVRSWSEPGEPAERLLEVAEAERVDTIVVGNKGVRGSRWRVRDSVPTMVVRHAPCSVFIVDTR +> +NNYRTIVVGTDGSALAGPTVARAALAARREDADLVIVCAFAEMAASTAIAEAVAIAQEYGATIGAALLVDGDPAAVLVNVATEREAQLIVVGARHHRSLAERLLGTVATEVTKRAPCDVLVVRP- +> +VPVSRLLLATDCSPAAGAAEAAFLELLRHCDSALVVVGGWVD-TIEDHV---SALAERAGEVFDAELLGRGRPSAEIARVAQEHDVDLVILGRCGHNVLAERLLGSTAEAVCQQARCLTLVVPG- +> +MIEGPIIAATDFSKAAEQAVAQAARLAAQRGVKLVLAHVIPPLAAEREMQRL--RQIESALTEVETVIAEGEPTRELAALCQSQNAALLVVGAAGAGNIVEAVFGSVARKMVRRAPCSVLVVRP- +> +--MHKILIPVDGSVHSMKALKIAADLAAKYQGRLCILHVLLRGIGEIILDHFAEKARTHGVEFELLPIVSGKPADEILKMQEKIEAGTIVMGARGVSHSDSSTFGSVSQEIFNRAQCTCISVK-- +> +-TSRTIVTGVDSSQTALNAAEKAAELAEGLGAELHVFCAYSISQARAVADAVAAVLREPDL-TIKASAEEGTPAEVLLQQARTLKADTIVVGNKHVQGFS-RILGSVARKVAAEASCDLYIVNTT +> +-ADKTIVAGVDGSETAAIAAERAAVLAQALDARLHLISAFGKFNETEVAAKAATLLRSPDV-TITTAAAEGKPGEALVSVAEALGADLIVVGNKRVQGIAGRVLGSIARDVAAHASCDVYVAHTH +> +-MSEIVIVGAVDTETANMAVDRAAHVAAALGAKLVVVTAYGDDTAEVFAEQTAARLQAS-I-ECVAVAQRGKPDDVILDAAKRFEATLIVVGNVRMQG-AARLFGSVGNDVTHHAPCDVLVVKTS +> +--MKTIVLAYDESPEAGRALEKTVELAKVLSATVVVTSVAPVMPPGRLAHDAVAILTEQGI-VAKAVTALGEPGHTIVELADQEKAEMIVLGMSHHPH-LSRIFGSVSEDVAHHAHCDVLLVH-- +> +---MALVVGYDRHPAGRAALVFAGELAGALNVPLHVVHVVNGR----ERQRVADALGAADL-QWTYHQIRGDPAEVLVQVADEHSASMLVVGRPQHGPEGHVVTGSVARNVLRHSRRPVVVVPEY +> +-VFNNIVVAYDGSDHAVDAVMKARDFALADPEVIHVVFVTTHPESEKVKAGLGVAIEGVEDQVTIDVIPGYTPADDIIEFAKEIEADLIVMGSRGLGAIRG-VIGSVSYAVLRESTIPILVIK-- +> +-PIRDIVVGYDGSDASARACSIAVRIAGLLGARIHLVHAGELR---AA-MELVRSYSERVGVPLRVISREGSPATAILAVQEETGADLILVGTRGLHAAPRLFLGSVSADVLARSRVPVTIVP-- +> +-AVKRIVAGVDGSDAGKLALEWTARLAKTLHS-EVVAAIDVP-KWCRPLKSVGV--------RYRAIIEDGRPASVILNVAERERAELIVVGRRGHGEVAELLLGSVSHEVVLHSKRPVLLVP-- +> +--MRRQLIALDGKDESYYALEWYLNNVCRSGDEAVIFSQFTLNKAEEITTKASEKIKTKGIKCYVIIKSGLKPEEAILQAVTEENVTHVIMGTRGLGTLQRAFVGSVSSTVVSNAKVPVTIVK-- +> +-GASQYMVCLDGSEVSKNSLRLALRLLRPDDDSLLLLWGYDI-QSESYLAEAEKLARESGAKQVTTKAVLGFPRDQILLVAEEEGVEMIVMGARGLSPIKKLLMGSVSSHVLSNAACPVLVVK-- +> +-AIKTILWATDGSESAQKAGAMVKQLKEGFPQAKVVAVQ-DQPQVFSLF-ERTP--------DIEFMVAEGQPSAQINKIAEKIHADLIVIGSHGYTAWDRFVLGSASRHLLDHTTYPVLVVR-- +> +---MKFLVAYDSSATAKHALERTLGLLHRDRDSLPELLLTEDT--IRVM-------KSLS--------DLLTAEHEILDQAAACEADMIVMGSRGMGTIQG-V----SQRCLNEAKVPVMVVR-- +> +-KYKNILVPYDGSKHSQKALGMAVDIGSMFGSTLYVVNVADLSTSELQLKKIHEKYRDSGV-SMKEFVLEGNTVDKLLKFAQDKEIDFIIIGSRAYLESQK------------------------ +> +-MTLRILAAVDQSIHAEHALRFAARMARGLNASLAVLLVLPP-KVRRILD---EEGVDAQLLIRKYVPTAASPASVIVEEAEKRGFNVIVVGAKGVTGREDVSIGSSALWVAAFAPATVVIVR-- +> +-MITSIVVGVDGSKSAGRALLMACEMANQFGAALHISHTPRDEAAEKLIDGARKVALDAGVEQVEVNVGQGDPARDLTEMAQAVNADLIITGRRGLGDLGAFVLGSTSHQISKQAKCACMTVP-- +> +--MKHLMVATDGSASADRAVDEAARMAKQSGADLLIVHVIGGYYSAQVLTQAKARAQALGVPDARLASYRGEIVPAILQAAQQQHIDAIVVGRRGTGHMSSLLLGSTAQKLVSLSPCVVTVVP-- +> +-MFRTIVVGVDGSECSARSLDLACELAKLHGGEIHLVHSPELVAGKKVMEQATAAASAKGITPATTTIGEDGPVDDILTIVQLYGADLIVTGRRGLSSVGGLFLGSTSQKLAQSADCPCLTVK-- +> +-MFDVIVWATDGSANADLALDYVRKLAEGGQSRVVVVHVKEVI--QKIYAQVNDLKRGVDASLRAHHAAAGHAAHITADIAREEGADLIVVGTRGLGPITGLLLGSVTQRLLQVAPCPVLAVP-- +> +-MFESIVVAVDGSDAATRGVEAACKLSEAFGGEVHLIHALENKLTSDVMDAAVKQVRSAGITPSSATVAEGDAFDEIMMIVGLYAADLVITGRRGLGTLSGMFAGSTSQQIAKHASCAFLSIK-- +> +-MFKKILVPTDGSEQANKALKVACEMAIAIDGQLNILSVFKHHYSKELVAEAKELAISFGVKNVKGFVRIGPTTKEILEFVKDKDIEIVIIGKQGKGDLSGYLLGGVSHKVAGLSDIPVLVV--- +> +-YFKNILVALDGSDHAMKALELAAQLEDKFDSSLHILSVYRHYIAREIVEMGCSRAKELGATGIKGVVKRGKPSRVILDYVKEHPVDCIIMGKRGIGDGGGGLLGSVSNRVATLAPCTCITV--- +> +-STPPIVVPYDFSTDSREAVDKAIALLGS-GEGIYVIHVLGELHATQAIR--KELADEKYS-DVKINIAFGDPGEQICHFAEKQGASAIIISSHGRSSIMRVLLGSVADRVVRLADRPVIVLK-- +> +-MIKKILVAYDGEQ-SHSAFLFGLDMAKKFDAEIEILSIVRILHYEKFFKLLRHEARSHGL-RIKTEIALGHPAEQIIHWAEKKKVDVIILGPQTKNTLGQWLLGSIPDRVVHHAPCTVIVVK-- +> +-MFGKVLLAYDGSQTADLAFTRALQVAQEAHAPLHVVAVAWSPQCWEYLNLLRSKATAAQV-VLELEVVEGNCSDQIVAAADRLEADLIVIGHRQRTLMQRLSEASLAKRVVDHAHCSVLIAR-- +> +NQFNRIVVGYDDTEGSNKALQLAVQMAKGNPAHVLVANVYDEKPTHAIISNSVKAKQELEPHIQKYDSLDGSPAESICDYASAEGADLIIVGNSGKGGLKRMFLGSVSSNIAKQAPCPVLIAK-- +> +TSIDRIILAVDGSAPAIEATKYAIGLAKR-NSEIIAIFVDPDGYGLAGLKLAHKYGKAYCINVK-LLLLSGNPVKQIINVAEKEGADLIITGDTGLTGIKRIALGSIAEAVVEASDVPVLVVK-- +> +MRFKNILVPYDGSEHADRALDVAGDFLRSNPARVHVISVTYVAVFSQEQKAAHEILPDIEPERVCDTIIRPSAVEGIEDYARRKKCDLIVMGRRGLGGLRQF-VGSVTKEVLHRVDLPVMTIK-- +> +MPFTRILVPFDTSELSVKALEKAVEISAI-DSPIFILHVISEIEMIVILEDVKNTYAKHNISIT-TEIKIGDPAEIIVDFTKQNNIDLIVMGSIGHKGISGMKLGSVARKVAEEVNCALLIVR-- +> +NLPKKILVAIDGTPISDKAAEEAVRMAAS-NGPYRSLLVLPNALRNRIFYVIQKNAGEAGVPLD-IRVAYGEPADEMLAIADHEKVDVIVIGSSGKGFIKRKVLGSVSNRVVQNAKCSVYVVR-- +> +--MYRILLATDGSKSMKRLVEEVLTIAFA-LAEVTILNVIEQTEADRIVDEAAKPFRDKGLIVKEVVDTEQSPADVICDFASKGGYNLIAIGSRGLRGMKELFLGSVSNKVAHLGCTNVLIVR-- +> +-MKEKILIAIDSSDSSSKVLAYGINLAGKLD-EVKVVHVIE--AGQELMEAAKKQTAAAKVPVH--ETLVGNAAQQILTAAKKSEASMILIGSRGMNAVAEFILGSVSSKVAMYAEIPVLIVK-- +> +--MFKYLLAVDESENAARAAQYLANLAGIWQLDITVVHVVNFK----VLNEQTVAFDKFGVTIK-KQLINGHPSDKITEFAKLNDFTHIVLGSRGLTDLQGLVMGSVSHRVLHQAHCPVTLVK-- +> +AMLKQILVGYDDSPAAQRALEFALKLAQG-FCQLQ-AAVLPAGLRPGLSQKVLERAAQAGVKAA-WKVVPGSAGDVLLAEVRSGSFDHLVIGNSGRGTLARWLLGSVMNEVVEHSQIPVTVVP-- +> +--MRKILVAYDGSDLSKKALNKAKAQIKFEPTELHVVTIVPNTDFKEELKAIREN-MNIRTSVI--DNYHWNAGMKLCQYAEEHNIDEIIVGSRGLGGMKKFFLGSVSNHILHHADCEILIVK-- +> +MLYSKILIPYNNTDLSNKALETVKNFAKVNPAEIDLLFANQVPYADETLQNAVNYLADLK-NPIHKYIVDSQPITAILNHVETNKNDLIIMGNRGLRGIKEF-LESVSHVVVQKSPVPVLLVK-- +> +-MIPTIMVAIDQDDASKAALLWAIELASILSAKVVGVHAC--G-----MDSIRKPLSDSG--LDELVLRDGNPVSVLLMLESEVGADLIVVGSRGHSVIGGL-IDSTSHHVSEAARCPVVIVH-- +> +TEIKKILLGIDGSDGSYKAAGYAADLAARVGTVTLMFVVSD-----SRFNRAKAIMEEKHVTYD--MVEMGNPAQKLIATA-ESGYDMIVLGTRGLSAVKEFMLGSVSSKVVQHSKIPVLIVP-- +> +MVMERLLVCVDGSKYSEEAVRYAVEIWRK-YSSITLIFVWHPPYEIAKLTEAEKILKDAGITYT-VIKKIGNPAMHIIDE-SKKGYDLVVMGSRGLGSVEGFLLGSVTSRVTHHVRVPILIVP-- +> +-------------------MDHAGFMLS-GTCHITILHTMRHLRIAPFMEKAREMLFEAGLTEERVVDGSRSPADDILKEARSKGYGTIVLGRRGLSGVKAFVFGSVTRKILHHSAGLSWIVQ-- +> +--MKKVVVCWDGSDGAKRALKAGQRLVDENI-EMVVSEVFEP-KAQKAHDEFENLA--DEA-PK--NKEAHSAREAICEEEKLGNVDLVVMGTRGLGIVSRLVLGSVSEYVVQNAHCPVMIVR-- +> +-MKSKVLIPVDTARNSLTAEEYALKLNWRMP-SVTLLNVVNTKVLKKAAEP----FSKAEV-D---RVVEGAPGLTICGLAQDENFDMVIIAQSGLSEWEEILGGSVVRTVLNKCQIPVLLVK-- +> +-VPKKIVVAFDTSLHSIHALKAAISISEKYRSEITVIHCVEYP---PLMKEARRR--KVKIEIVYT---TTSVAESLLLESKKIKPDMIVMGSRGLGGFKSLLLGSVSNAVVTHSTVPVLIIK-- +> +-PYRKILVPCADEVSAAAAITTAAALATVFD-EVLVLHVVHPRKLAPVLER----FAAAGV-S---YLETGDPGSKICELAAAQRADLLVMTRRSLGFWDRLVGGSVTEYVLRHAPCSLLIAH-- +> +-MIKRILVAYDDGRQAQKALEAAIEIAENTGAVIYITSAYIIPYLKKILQEAADNVSQKNI-PVFT--LDGSPGKMVVQFAENNQIDLISVGSHNRSAVNRFFMGSVSNYVLQHAKCLVLVAK-- +> +-LFHKTLLPVNDSPQSERAVQKAIELYQAGV-DNLLFNVYDTSESLQVLEKYQKMLADHNI-P---KKAGGDPASLILDLENDGQFDLIIMGSRRLNKFQELAFGSVTDKVTRLVNIPVLVIK-- +> +-KSQKIAIGFDESKYSKKAVEYVINNFE-KS-TVYLIYV--EEKTKKELIKEVEAIRKKGF-K---EYIEGYPPDKLVNEAKRKNADIIVVGSRGMGKWKGSVLGSVSQKLTVIARTPLLIIK-- +> +-MFDKVMVAIDKAEITNKLLDATVEIAQNKQ-QITLVNVSQD-ASLDLLHQAKSKLKSAGI-NPETIHLKGDPAYEILNYARETGQQLVIIGSRRLMGVKGMMLGSVSHKVSQLSNCPVLIVH-- +> +-KFEKILLPFDDSTYSINAAHCALSIAKQMGS-VTIINCYDLNKSENILKVAEEIFRDRGV-DYTLKPIRGLPGKILADISKSKEYDLIIMGSQGHSDISGLFLGSVTHKVLSTMYCPVLVVP-- +> +-MFSEILVAINGNAQSDKVLE----LAMRVA-DATRVHVVSVIIVEKARLF----LQARHI-K---TVIAGDPEHAICNHAREQGCDLIVMGHHHMSTFERLVGNSVAYEVLQNAPCPILIEA-- +> +--MNKILLAVDGSAYDEKSVAFINDKAAKVC-NIDVYVASVLP----KLLTNTVQKLTVHG-NAS-HILEGDVAKKLLEFAEQTGVDLIVMGCRGLSNYEELVLGSVSMKVIRSSSCPVVIVK-- +> +--MKKIVLAFDGSTHALNAVNEAKKLMQGFPSSVTILEVLDIARKAVRIDEVKQQLIGLLD-TFEISILIGDPASEIIQHVKKNDYDLLIMGSRGLNLLQEFVLGSVSHKVMKYVSIPVLIVK-- +> +------PVDLKENGYSPAIAKTALALANAED-EIYLVSVLNGV----KLMAFAEQHMGVDN-R---HVLLGNASEEILKFAKAKACDLIIIANHKTNMLGNPGFGTITAKVAVQAACSVLIVK-- +> +-TNYKIAVGLDGSDSSWKALEEAVKQAAAKVAELHIVSIQEASKLERVQIKAKTLAENAGV-KVFAEITTGSSTTVMVDFVKKNSMDMLIIGDTGHSSIWGALLGTNAEKIVRNARCSVLIVR-- +> +-MFKKILVGNDGSEGAKKALRVAIEMAKRYGAELHSISVEEPHYFAKINGEAKEISARERV-VLHTNVLAGHEVETIVDHDRDHHFDLAVVGFMGHSKIYDRVWGSTSQNIARLVPCTVMVVK-- +> +-MFHHIVHANDGSENSLTALRTAIELAAVADTGLDVLFVEDAPHIGRHKALAERIAARSGV-TLKTHVFTGHPVGHIVAFTREAKADLLVIGATEHADLWEHLFGRRSDRMTHKVDCSVLIVR-- +> +-MFQRILIAYDGSPESKKALETGIALARELKADTSLVSVIEPGKLGAMQAEVKQKAAQSGM-EIDTLLVEAGEAEGVLEAVRETQAGLLVVGLRPHDHTVE--FAGTLRRIANQIHCPVLAVP-- +> +--MERQSSPHVSSEPAVKALELAIAMARQNAAALHLVCVEEPQRFRPVVERARLRAEQSDI-KLQVHLVSGHPVRMIVDLVDEIGADLLVIGATGHSALYERMIGSRADRIVQLAACPVLVVK-- +> +TVSRRILVGLDGSQNAFDAFECYMANVHRPNDYVIVAYSPNVSERAMNVRKILEQSEVRGC----VHLPNSNVGHAIVKEAEKENVELIVIGSRGHGVIRRTILGSVSGYIVHHSHIPVLVQP-- +> +TPIKHILVAVDFSPMALYTTRMAAQEAQLHDARLTLLHIFNPQLAHAEMEKLRQSVAAGGIPQVELEESGENIGKAVIAFGKAHAVDMLVVGSHGHGAIGRLLLGSVANDVVHYASCPVLVVK-- +> +-MTTPVLICIDGSNLSHQAATAGLKVL-RTDAALTLLTVIPEPAQRADAEALLATQKELGIASAEHVVLMGPAGALVCEYAANVGAEAIVIGSRGHGGIRRAILGSVSDHIVRHAHCTVLVTS-- +> +-MYNKILVPFDNGIRSQRALNTAIELAKKFQAKIFIFTSLNIFRSRNNIEKALQKVKKEGLNISDKDDLEDIPGESIIRYAEKEEIDLIVLGSNNLGVFDRVFLGSVSNYVIHNAHCQVLVIK-- +> +FP-NRILVNLDKSAPAQKALEMAMQIASATGSELHVVH-----AAEG----HLKELLSEGAPASNRHVRAGTTDNEVMRLAQELKAGLIVVGNRSADAISRIVLGNAADSIVRHAHCPVLVVR-- +> +-MSGTMLVAVDGSPEGYNALIWVLEHIKE-EGRACALYVISPAEKEQVINRIKELAHDRNV-DIEIIVRTGDPRSEILQTAEEVGADLIAVGSTGKGLGARILLGSVSTYILTHAKVTTVVVR-- +> +TPISEILVPVDFSECSRRALQYAMRIAAASNAHIHLLNVIDDPQFLNVMSPE-----DRARFRTTTSIRFGTAYHEIETYAKEHDIELIVMGNSARSSLSSAILGSVSGHTIRHAVCPVMTVT-- +> +EEISKIMVGIDGSEASIKAVRKVLDMAKKYSAEVIAIHISLIPQMKIWLKNIMIEANEKNIFKALVKETTSSIVNEIIRSADAENIDLIVLGSTGKSRLDRMLVGSVAQGVMTNAKCSVLVVR-- +> +MELKKLLYAVDLEDAPHPAIEHVKMVASLTGASVSIVYVLPSEPTQALLEKMEHTNFPEG--VDDCAFLMGKISEEVVKYAHKSDIDCIVVGAHGRIGFRQLFAGSVATEVVKKAHCSVSVIR-- +> +TEKNNILVAVDGSKAAYEAFLEALKYKETAK--ITLLSVIDQALAENYL--NQLAENAHTKHHIEKVVLEGNANKCIVQYATEHVIDLIILGKTEKNLIERVVLGQTATYVTKHAPCDVLVK--- +> +EQYKNVLVAVDGSDQAYHAVQEAIEIVKRNDGKLWVLTVKETNMGSDILAK-VKELVNGQVELDATDLYDNNAKRKIVQYAADNGIDLIVIGSTGTGMIDKLFIGSTTQYVVNHAPCNVMVIK-- +> +---MNILVPMDLSSHAQLALKEATKLFKGAN--FIILIVVDIII--NAFIERQKEMFPNVIIE--FDVCSGEAKHQIIHYAKQHEIDCVVMGATSKRALSKVILGSTTDYVVKHINHNILVVR-- +> +-MTKKILVAIDGSENSFDGLYEAIDMAPKTHADLNLISVVNDADAEFNLRKAESIVDNSGL-KCKIRVLYGEPQDEIIDYASKHKVSLIIMGKCRARGVERILTHSVGNFVVNHTKINTLIVN-- +> +MP-KHILVGYDGSETARRAYLLALDLAACAGAAVHVVSVMQWEDRLNGLREEVEALQPDPGVPVEVALVHGSPGDALLSYVAQHGVDHIVIGHTERGALARWLVGSTSTDVLAKAHVPVTVVR-- +> +NFYQNIMLPVDGSQESIDAFKRGIQQAKLWGSHIFLVHVLPEDSFLSALENY---ANSQG-VHIHKELIYGEPRTQITKLVERWAIDLIIMGATGKGRIAKVLLGSVTSYVIRHAKCDVIISR-- +> +MLFKNILLAFDGSTASSKAAEYAIYLCKLEGSPLTFLHVLDHIDAEKWIKPIQERATTEGI-KSTIAILDDNKVETIVQFIQKDNIDLVIMGSRGLSKFKQMLVGSIASGIISHSKCPVLVIR-- +> +MSRKKILVAVDGSEYSNKVLDKAIEYAKLL-GEIVFVNCHKRFGAEKLVKPFLQRFENENI-PVEERLMEEPAGTMISDIAKIEKCDLIIMGSRGLTNLASMIVGGVTNRVLQTAPCSVLVVR-- +> +-MYRHILLAADGSKHSERAADHAIHLASMSNAVVDMIYVLDYAERRSRLLSIENKLKQAAV-PYQMTMQHGDPGPAIVSYANHHDVDIVIIGSRGAEHFAGNGARK----------CQP------ +> +MSFKNILVPFDNSSFSKRAFNLALDIAQKYDSTIIVVSCIDLLARKQLLKEIIPLQTKKGI-PFKKIIESSSIGRALLSFAKTKNIDLIIIGSHGKGFFDRLILGSITNRIIQQSHCPVLVVK-- +> +SFFKKILIPADNSKYSIGAARLAIQLAQLHESQLIFLHVVDVRSGWKVLYSLEEEA-AKHV-QVALTLEEGTAQRVILDVAEKYSVDLIVMGKHRKSGSKDVVLG----PIIENSECPVLIAK-- +> +-QYSNILYCSDFSEEAEMAFHHAVDFCQRYGAQLHMLHVLHSGQAESLKSRYGDRL--ECN-QAVFAVRVGVPFVEIVRYAREHKVDFIVMGASGSSELDKQTFGSTVENVARRAHCHVMAIRN- +> +-VYKRVLITVDGSEMSKTVFERGIEIAKREGSQACVIAVVDTTALKKFISELRQYC---DY-GFDEEVRTGVPSKEIISYADQWGADLLVVGSYGKGGWIEFLFGTTAERIIRTAKSDVLVVKC- +> +-MYQTTLVPTGEGVAALDAVDDAIDVTAADGTV-HVLGVVEEIELEAAVDRVATAV-DAGI-DSETAVESGVPAHEIAAYADAVDADAVVMGKRGLDAAAGDLLGSTTERVIRNADATVVSVPV- +> +-MYDNVLIATDGSDATEGCVDYALEIADRTDAKVHALYVVETKYGRETVTEIVEQV-DRGL-EGDGVIKTGRPSEKIVEYANDNDIDVVVVGKQGHGAVDR-HLGSTAENVMRMVDDAATVVVE- +> +-MYDTLLVGVDGSDFAQKALEHAVELSQAVGATLHVITVVDSTAKATLIENITKTT---ND-DITAEVRRGDPADALLAYAAEIDADLILVGQSGAGQLEATIFGRTTEQLAEQTQIPLTIVPL- +> +-------------MCTR--GDGPIDLAATDSATLHALYVIETREGEAVLESVETES-ERDV-AFVDRIETGVPERVIVEYAESEGIDIVVLGSRGKSAFKAVLLGSTSEVLVRDLSIPVVLVSE- +> +PVIHHVLVPTDGSENAERAVRFSAQVADRRQAEVTVVFVHLLVRAQEIVDRAVEEVR-GLVTTVTRVVIDSQIDEGILRVAEETNADIIVVGTRGLSPLRGAIMGSVSHSLIEKARCPVLVVK-- +> +IQYKQILVPIDGSENSCRAIAAAVDMAELSA-TISILYILTFSFAKSMLKDAGKLIP-KHI-PRHTYYEIGEPGIAITDFAQRNHYDVIVIGSRGLNFLSGIWQGSVSKYVTANAQCSVLIIK-- +> +LDYKRILVPYDGSEYAKRALDRAVSVARCCGAKLFIATVSRPMPGQVILDDSEKLIP-EDI-PHELIFRVGNPGSVLLDLSFEKNCDLVIMGNRGRGALKSLFMGSVSSHLASNVKCPILIIK-- +> +KSYQHILVPIDGSDHSKQALQHAIDIARITGAITLLSVANDIINSTGLLKKFAAMIP-ASL-SVQSIFELSAPEAAILAEQKSQSADLICMGRGGGQALKNFLLGSAQHLRHHPRTLPGPLGP-- +> +--MDKILLTTDGSENSLKAAEYVAGVLKKLNTSIVVLTVIPRDRSKFIIEQTIKPLI-K--YNIETMIKVGVPGETIAEVAQEIAATHVVMGTRGNTGLKGLFLGSVAQRVMQLVNIPLTLIK-- +> +---MKIVIGFDGSENSRKAVNFLGNFCHTMEIFI--VNIIELQETRKIRNEICKEK--SD-KDI-KIIESNRIAPAIIDFAKAIEADLIVVGSRGLGQIKRAFLGSVSSELIEKSPFPVLVVK-- +> +MVFEKILVPYDNSPNSKLALKKALTLAALTKSNITIVHVIAYHHVKKFLDDAKKEAH-KK-NKTEEKILYGNPSEEILGLMKKKKFDLVIMGKRGTTKLTGPSLGSVSNALVQTSKVPVLIIS-- +> +--MNNISVAVDFSADTPFIVDHALTLAKANDSKIHLVHVVGANQVKGELRKLVDFIL-DA-GEADSALVEGSPAPSIIHEAEHVDADLILMGARKHGLVGGAL--SASQGVLRQSTIPVYFVP-- +> +QPIKKILLATDGSVSSVRATKFCVGLAKKINAQVLAAYVTGQ-PSEAGLA-AKAFGQKNGV-EINTTILRGSVPRNLIKAAEADNVDLIILGDSGRSGFSKISLGTVAETVMRLSSCPVLIVRA- +> +AGFRKIVVALDFSPASERALALARAQFPG--AQLRIVHVTDARTLEDA---DASRLDRRLRDGEEVEQLVGDPVTGIVAAAERWGADLIVMGTHHQGALEHFFMGSTAEKVLARSAVPVLAVPV- +> +AMTPRILIAFDGSSPAGQAIVRAVEWVHGTGETIRIPVAIPPHFVEK----IRDLTEEHGV-QIRLHWRRGDPRHEIVQAATDLGADVVVIGSRGHGRISRLLLGSVSSFVVE--HAPVSTLVV- +> +---MHALITTDGSEVSIEAAQKAVRLLN---PTKITLLTVADTTARNAILDTVASLGVDPS-IVEHKVVEGSAGIMICLVAKQTNPDVVVVGSHGRGWFKRVVIGSVSEYVSRHCVAPVLVIRH- +> +PQVNKILYCTDLSKNASYAFQYAVYLARQTGADIHVLNVVEQLSREEFLHQIAPTEKALRTKIVGCEVVEGYPVQTILRRSRELGCDLIVMGAHEKGWLHT-LLGSVAKNVLRESRIPTLIVPR- +> +RVYGRVLVAVDWSRASDDCVEHGAVLARRMGAR-MCISVWETPR----------ARRVAGAGLGEVRVVRGNPGREILRYAEEEGFDLVVLGRRGGGVAHRFRLGSTVHRVVSCCSCSVVIVPP- +> +QSVNSVLTPIDFSENADTVFKAAVFLAKTFKAELHVVFVVQNFKMESFIAQHKGLCDEAGISAVSSKVLSGDVGEEVVKYAEQKKVQLIVMGTHGYKGLERIMFGSVAEKVVKTAHCPVLTLNP- +> +DEFDDILVPTDGSEAAYNGAQQAIKLAQRNAATVHVLYAIDMGKGQTFVAEIEALADDAGV-ETVTTVTPNTPLQAIREYVDEHGIDLVVMGKRGRSDPDKPLIGSVTNRAIGELDVPVFTA--- +> +--MFKVLLATDGSEYSEKAARYTGQLCEKMDDCEVTALYVKDIM-QEQLDTAQKVLARTGQ-QPILRSTWGRPSEMICRIAEEEKFDLIVLGRRGRGQIADFLLGSVSDRVSHCAKVPVMIVHE- +> +IQLSKILCPTDYSKTSEKAVRYAIELGRKTGSHVRFLHILQPEK-DDIVTELLMEEKKKGL-SAEVLIIRGNPYDAIIDQVRAWGPDMLIMGSHGRTGLNRLLMGSVAEAVFHAVDIPVLLVKQ- +> +DEVKKILVPVGFDAFTEKELEIAANIAKRYDAEVHILHVYQD-KIHSSVEEKLHQLVAEVRMPAKAVAIKGEIVDSIIEYVKNEQIDLVVLATHGRAGISHFFLGSVAENVIRFSPCPVLTFRT- +> +--MLKLLIPVDRSNASRHAVKHVIRRAWGG--EPHLLYVARS-SGVE----AAELLERGGV-PYVAHILYGDPAEQIVRFAETNRFGGIVMASCGLGSLPELLLGSVTAEVLRTSRIPVEIVPV- +> +MLYQNILVPFDDSEAALAGLKEACRIGLHTGAVLHIVHVI-DLIFKR----EFPNLNTH-----CTVLEAVKVASLLVHKLEEWECDLVVMGTHGFSGVKHLLMGSVAQDVIRQAGVPVTVIRV- +> +---MRL--RLES---------TSHDIAHGCIAAVYVISRLSHL--KQATQ-AEDLARMINV-PCQKIVVQGNPSIEILKSAREIEADLIVIGSMGRTGFEKILLGSVAEKVVLQSSIPVLMIKE- +> +MDLVRVLIPLDGTSEAEAVFDLLKGDLNSN-PEIILLQIVEPV---R----LKGLAEKYGN-DWRCEATIEGRADGIVKFASKENVDLVVMLQHKRNRISXLLMGSTADKVSKRSVIKVRKFTF- +> +-MYDEILIPYDGSDEARKGARHGVELAAALGSAVHALYVIDLPYGEEVLEEVANMAAEHGV-DCSATIRSGSVSEEIVDYADEAGTNAIVMGSAYRGKLGNI-LGGAADRVVRSATVPVITHRM- +> +SHYKNVLVAIDGSAESRKILGKAQTLVKGSDAVLHAVLVYET-FQEQ-IASMLKAEFPQIP-ASNVHFLRGKAADEIKRLAKSLNADLVVIGSHGRGAVKAAVLGSTANSVLHGIHCDVYTVRV- +> +MWCSKILVAYDGSAPSAKAIDLARAIAAQDERVELVVHVLKLYEADRILHD---LQRTADVPNAHAKLLKTSPADLILKCAQDEGCDLIIMGSRGQGGVKG-YLGSVSYAVVQGSPVAVLIAKD- +> +-MYQNVLVPVNGTEISETAIPHALELAEKHDAVIHALCAYNRERAQEIAT-VADRA-DEGI-EAVSAVSSGDPADSILDYIDEKDIDIVAIGARKRSPTGKLLFGSVTQTVLLHANIPVVVTGS- +> +-MYDRVLVPTGVSGPDADGRTVGLDVAQRYDADLHV---LRIEVEERA---------FAGVN-VVE-AARGPPTDAIETYVDE-ESDLVVMPERGAFCDEPYRLGGVVGRYLRESPVNVMTVRT- +> +---MKAIIAVDGSEGSLEATRQAVRLHPQVDQFVLCY-VMRWSEAEVPMQKSTEIFTAAGLPPQRIERPLEGVARQIVLVAEEEKADLIIIGTRGRGDLSSMLLGSVSRGVIASSTVPVLVVPP- +> +TDGTLILLPVDGSETCRRAAEYCAWFARATGGRVLVLNVQPAFLAKT-----AALEILAGT-PNEFLMAEGEPAETIGRIAAEKNCTHVVMGTRGLGKVSGVLMGSVAMKTFHLVGVPITFIR-- +> +-MSYKILVAFDGSDGSVNAANFGFNMAYYLPDVIIEITVFTFTKAEKINSI---FLKKTDNNPFSLSVLDGNPAKEIVKYAIEEGFNHIIMGSRGWGKIRKLLMGSVCKKVLENSHCSVTVVK-- +> +--MQKILLPVDIEKLSDKTFKITCDLVQKLDASLVILSVVPFSYAEKIVKDIAERFKLKDIN--QTVILKGNPADEIIRYSEEDQFDLVIMNTQNINSTKRFFVGSVTNKVVHNSNVPVLIIS-- +> +MSHTKMLISIDGSVYSEEVLEAGMEIAKSLDSRIYVVYVVHPGMGKDAFR-ATAIAEEKGL-SCETKMLEGYPSDKIMDFAERKSVDMIVIGSRGQQSTREFLLGGVAEKVIRNSKKPVYVVR-- +> +--MKKILAAVDGSPLTHNVIMAAVEECHG--AELHIVHVLENASLLS----MKAEAEAQGG-EAVLHLLRGHPGDRIVDCAIDIGADMVVLGSLGRSQVKRMIAGSVSTFVVT--HCPITTMVV- +> +MEITKILLPVDGSEYSLNAAAEALDLAKKFDAKIIVLYCSETFYANHVL--------KHQA-KFTEHVVDSSPSIEIPRMAEKENVDMIIMAPRGTNPLASILLGSVTTRVLKQAPCNVLVVHK- +> +--MKHVLLPIDGSTRSLRTIDMVQQTYRPQDTEVTLLMVLPDQ---DRMAR-FAAL--LGW-TVRTELLWGSPGPEIVYYARERGFDALVMTRSSRGPLQK--LGSVATYVVRNAQFLDLIIMR- +> +MEYERILLPVAGDGDVDPVVDHADSLAAALDAELLALHVVDPDRGPEAVFEAVADRVDETV-SMRRVTAEGDPGESIVDAVRDWECEFVVMGTHNRQGIDRLVTGSVAEHVTRTAGVPVTTIAV- +> +-----------------MALEEAAELADKYQAALTAVYVIPQAEAKKVLADMTVTYRQRGI-RITEHVLAGGPHIEIIRLVERVGADLIVIGAHRAAGTKPVLMGSVAEKVMRQAPCSVLIVRE- +> +SPFRHLLVAVDGSQAALQALDTAAELAHAFHSRLSLVSVYRHFLAEEALLQAQTRLTQRGL-RADCHLRRGTPATVILELADQLSVDAIVLGSHAEG---DRLFGSLADRVSAQAHCSCIRVRG- +> +MSFEHLLFVIDDDQVSPTAIHHVTQLALAFNSRLTLMSVVSIDTEAKILAQLKHQMLQGIL-NIHTKVIHDPIATGVLTVADEINADLIIVAAKNRNSLKKILAGSTPNAVLAISPLPVMVIN-- +> +-MFEKILVPLDGSENAFAALRAAFDIAKHYDSKIYAVSVANDQQAEVALNQAAGEAKDAGI-VLETHFEVGPKQAIAESLPERLGTTLTVIGKSGAHGLNRAIMGSTTAYVVRRSTVPVLVISQ- +> +MVYQNILVPVDSSEESFAAIQHAIEIAKAFQSEITIVQVLTLDRARTFIQANLQNVYNTNV-DIKIRLLEGSVTHTLINMVEQSKTDLVVISSHGRSGLKKLIWGSITQNLISELNIPIFIVKP- +> +MSYKNILVAIDLSKESRQIISKAKETAEVYGAKLHLISAIEPLEAKERLL---AITEDLGI-PSKNCFAPINPANEIRERAFKLKSDLIIMGTHGRKGIKKLILGSTANSVLNGTKVDVQVIRI- +> +MVFSKILVPVDGSSHSDRAVEYASEIALKFNSRLILLHVYSFI----TINILSEKAKKSKI-KNVTCLLREVTVPEILQVAETEKIDMIVMGARGVTGIKLHVL--------------------- +> +RRLSRILVPIDDSKPSMKALELAMDLAMKYKSRICIVNIIPTHEARSLLISTLL--IR-SI-GIESIMGKGHPASEIVRIAKEENIDLIVIGSKKPSIFAG-LFGNISRSIISKAPCPVLVVK-- +> +MDLRVILVPYDSSHFSENALEYAVYLAKAIIIKIVMLHVVQEILMQNDMDKKKKAYSIEGI-KLESLILYGDPSNQIVDYSNNNRVDLIVMGSNGLQGLAKKGLGSVSRKVSESVSCPMTIIR-- +> +TGKPSILVPYDATELSIKALDKAIEIASRMGYEILLLYIIDDTGAEKCMTEVVGKIKEKEL-FVKYIIRVGHPDDEILEVSKNPNIHLIVMGCGSFKKRHNRGVGSISRWISEVASCPVVLMR-- +> +-MTKTIFVPHEDNEASAKAIKYAIEIAKGLNMEIKLVRVVPEVQEAEKLQKHVSKISK-GI-KASATVVEGVNAEKIADLVRQERPYLVVIASKRRGSLAKRMLGSVARRISEESTSPVLIVK-- +> +MTFNTILVPYDGSAHALKAFNKAVELAKQHHSQIKVVSCLNIAKAKKLTKDLFSKLKN-SV-SVDFKIIESNNIKSLMLFTKSKNVDLIVMGSSGRGGFDK-LLGSVSNGVMQKAKCPVIIIK-- +> +-MISKILVPIDGSPLSKKATQKAVELAGQLDATIVITHIMDQKNAQDIIKEMVDYVSE-DV-AVESMLLFGSPEYDIEKVARKSEADMVVLATHGFGLKSK-LLGSFSNAVVKYVKLPIVLIK-- +> +-MYNKILLPVDGSKNSEKAIKHATTLAIDEEAEIVILYVVDHRQGEVVTQRVVDQINGKTI-KTEKLIVEGNPANIIIKAIEKKDIDVVVIANSGKNFVDRFLIGSVTERIIRCSTVPIVVIP-- +> +-MFQHILLATDGSESAHKAEDYALYLGGACGAALTVLHVQEDRTGDRILREFSRK---RGV-PYTFKMKQGVPADEIVATAMQEQVDLLIIGGGHAGWLKGFRCRGVADKVTAMVPCTVMTLS-- +> +---MKVLLATDGMPHTDRAIDYAIDYASRYRAALFVVYALSPGEGKETVQGIKQK---REV-GITTMLEAGEPAEAIVRTADKIGADAVILGASGKCEGRKRPLGSVSARVVQDACCSVFIIR-- +> +-MYNHIVAAIDEARTSRLALKHAVELTRLSGAQLTLLTVVNPTEGEHILNEAEQYARHEGLVIIISTKGVKDMAEKLIRKAEESGADLIVLGTHGRTGLMHFLMGSFAETVLRQTTLPVLILRSR +> +-PMNRILVTTDGSELGQHALSHAQGLAKALGAELIVLSIQTDPEMKASLENLLHER----VPIMVERAQGRHVSRAILDVAREEGAQMIVMTTHGRSGLGRALMGSVAQAVAQHAAVPVLLIKGD +> +-IIEKILVATDGSDVAVRAAQMAVVLAHTGARRMVAVSVAQPQAARAHVETVARIAKSGGVSCEVLVKLASSPGPEIVQTAEDYECDLIVMGSHGPSAVERGYAGSVAQYVLARSAIPVLVLRDP +> +-TARHILVATDLSPSTGPLFAVASSLVRP-GAEVIGLHVYTPE-----RAEMRFQADQAGIPIRFEIVEGWSVPEQILSAATRFGAALIVMATHGRTGLRRALMGSVAEEVLRRAGTPVLIAPTA +> +-MFKKILLPTDGSALSAQSANAGISFARSTGAEVVALYVTQPFLAQKHLKAVADRAETAGVKVSAHAVSNFNIADGIVQAGIDYHCDMIFIGSHGRSGFSRLLLGSVTTKVLALTHSPVLVYRVK +> +-MFKHILVPIDGRPAMKEVLDKAVVLARTFGSRLTAVYVLDPQAGEQALQAASLALRAAGQPVETAVVEEATAWRGILHAAAQAQAELIVMGSSRRKGLEKLVLGSVAESVLQNTTIPVFVVPST +> +-MIKKIMVATDGSELAEKAAAYAIDMAKQLQGELLALFVMDDSIGEEAIARVREMGKEKGVKVSGKLIGSSSAVQGIIEAAKEEKVDLIVVGSHGRTHFLDVPVGNVTRKLVARKPCPVMVVPVS +> +-AYRSLLVATDFSSCSRRALATAADMFPD--AALHVLHVYDVPQARRDLEAFLDHPDLSQINRISIHLGHGVMDAVVEQTARDVNADLFVLGTHGETGFLQFVVGSRAESLLFWSRIDTLIVREV +> +-MFTHILLAVDGSRQTPRVVALAAGLAAASGARISVTCCVDASAAARIVREAAQLH-PLGEK-VTGQVIVGDAAQALVAEATRQEASVIVMGHRHRGLVDRLLKGSVCADIMATAPCPVLVEVRD +> +-MFEKIMVATGGSPWSNNAVGTATRLAADINRELHIAHVLEDDTGRSILQQATERAEQAGV-TYTTHMVWGSIPEQLVHIAQTEGCDLIVMGTRHLTGDKRLMTGRICNAVLATSPCPVLVVPLV +> +-EGIKVLVAFDGSKESRNAVSEAADIANRFHGSVTVLNVYWDPDAEPILKEK-------KAEYSLRPERDSNVPKTILRIAEADGYGCIALGSRGMGGARAWLLGSVSSKVIAEAPCPVIVA--- +> +-MFKKILIATDGSEYAVRAAEVALDLAHKTGARVLVLSVIDAGAAEGNVEYVLRLAADVGV-EATGHVLTGRPNIEMVNLTNSEAADLIVLGRHRRRSIGRIMRSDLAVRLMEDLDCSILVVV-- +> +---MKILVPVDSSDAALAPVARLQALARSGIDEVLLLNVQPRFRSRAAMARAIEALSLANI-RFRAVAEVGQPAERIAAIAERERVDEVMMGVGRHPEWLRWLNPSIAQGVMSRTDIPVTVLAR- +> +--FRRILVPLDGTKLGEAALPYVEELASITKAVIL--LQVVKPAASEYLNSIKEGLTKKGI-AAQAIVDVGSPAEKVMACAREKKIDLIALSSHGHPGVGQRTLGSVTYKILHYADRPVFIVTP- +> +--FNKILLATDGSKNSLHAAKTAINVAQSTQNTIYIVYVIKFSQRQEKIQSTVELIKASGI-NYRTRFLRGEPGSALVKYANEGYFDLVIVGNGRKNKLQELLVGSVSHKVAKGATSPVMIVKA- +> +--MKTLLMAIDRQAMAEKVINVTLEQAKAHQAVIILCCVAPDDSAEQIVRYALNPFAEAGI-PARGMICCGDPATTIVDQADRLNVSMIIMGRRHLSAFNRILKSSVSAAVLERAHCPVLVDVS- +> +--RDRVLVLIDFSESCFQALEETMQEMDNPESHIL--H----VRVKKAFYKRCGTPPY--E-KAPFTVLIGKPAKRIIDYAKENKIQLIIIPSHAHKGLNRFALGSVAERVVRQAPCPVLVLRE- +> +--FNKILVCLDGSKESEKILPYAEAQAKAFGSLCL--VESVGLLAVGYLAMKAAELRSKGL-KAEYSVRSNEAGESILDCAEEGGYDLIALATHGHCGLVKFLSGSVADHLLHKSNVPLMIIKS- +> +--YKKILLPTDGSEFAEQEICKVKNVLDPEGE-VVIVSVAMKIESEAYAEHMKVQLEK-GV-NSKIRVVCGRPAEKIEQVASEEGVDLIIISSSGKTGLHKFIIGSVAEKVLSIAKRDVLLVHE- +> +--FDKILLPTDGSEFSEHEVERAIKALADDGE-IIILSVASKLEAQDNVDRMAARFDE-RV-NVKKMVVKGIPSDVIVDVAEKEDVDLIIISASGKSGLHRFFIGSVAEKVLKSTERDVLLIHN- +> +--MAGILLPVADMKYDKKAFDTAIEIAQKLNLKITLINVQNIDISKKILENAKTFFEGKDV-EVDIKTEYGDPAETIIDMAEKQEFDYVIINSHRIDSKKRFLLGSVTNKVVHHATRPVLVIK-- +> +-PLDDILVPHDTKKESVAAAGHAFRIAQMFDSTVHGLYAVESSQGDAALTQMADRAESRGV-S-VREIRTASATQAILDYAEENDIDMIVMGKGRRKIDGPSTIGGDLLHVLQWTDIPVLTVSN- +> +--MERVLLPTDGSDCAETAAGLASRIASDYDATLHVLHISETVTDCEAIQRIHQQARGYGA-EIEAAISSGYPFREIVRYVELRDIDIVVMGSHDRTGLGRVLNRSTTKNVIRRSPAPVLTVPQ- +> +-STERVLVPFDFSDEASAALTNTLEFVGDASRVLHVLHRLETTDTRRNVQKAFHEQPPEGL-R--FDMAIGDPSSEILDYAKGNNITLIVIPSHGRSGLGRFFLGLVAEK--------------- +> +AKDRPILVAVDFSDDSKAAFTWACEAATAFGAPIVLFHVVHEPVAEKMMRKFLKERSDALK-NLKTQLVTGLPVTRVLKAADKVNARMIVMGSQGRSGLAHLLVGSKAEQVVRMAKIPVTIVKAT +> +FAPTKILVPIDFSVSSQAALNTATGLAQHFHAEIYLLHAIPMIFLETALSEMASVLTSLGI-EANFGVEVGNIVAPVLMVEQREGTDLMVISTHGMSGWRPMIFGSTAEKILKLAQCPVLLLRSA +> +--MRRILVAVDGTQASREAARTALEYASGMSSRVTFVHVLPERYAEALLKETCANTQSRHPG-ANTLVAHGEPAAVLSELAEEEDVVLVIVGARARGSLARTLLGSVSGELMCRCPKPVLVVP-- +> +-MYHKILVPVDGSYRAVEAAEYGIELATQVKGQVTLCHVIPATNGRSLLERMHDVLLRDGIN-LDTVLLQGNEAYEICRQAREGKYDLVIMVGQASG----YLAGALTNRVTQNAPCPVLVVR-- +> +--MKKILLATDGSDSAMHAASVANQWMEAWPAKLEMVYVTQVYRFTA-----AFEGKLDRVA-FSHVTDVASPAIVLSRIAEQDNFDMIIVGSHGRSAINRMVLGSVSHGLVNRAKVPVLVVR-- +> +LPKRKVVVPFDFSEASRKALEVARTFVPDAGGTISVIHIIVPPPMARGFTVLR----DAGV-P-AHVRVASNPAEELVAFAERDRSELIVISSHARRGFDRWLLGSTAERVVRLAPCPVLVLRGP +> +VPFRQIVVYLDGSESSMTAIMYGIKLAKEHDAKLMAVYVINTRALEDDLQQDARLASQKEV-D-ETVKLEGAVHIVMKELLKTQKADLLVLGGITDIRSRREELASETDRMMRTSPCPVLVVRDD +> +TRYQKILVPLDGSGWSQRALPHAVDIAMSNKSELILLSIFSAPAQYDSRILYLE-LRESGI--TE-VVDGSDAAASICNYVRASNIDLVVMSTHGRTGLARMIFGSVARAVMECAQVPTLLVHPD +> +PTYRKVLVTTDLSPTGNSAIPHAYAVLAGLGGTVILWHAIDLS---ASLFSSLEEARAEGR-VTRVVEAPGVIQEAICQDARTQGADLIVMASHGHSGIKHLLLGSVAESVLKSADRPVLVVLSR +> +-MVTRIIWANDGTLSADRALPVIKDLIASTGASLTVSYVHRDW--LPL-RRRV----AEGF-DALHDNDGGHPAQLIADLAQDEGADLIVAGSHGRGPVAGLLLGSFTSHLLKVAHCPVLIVPWR +> +-MHQRILAAFDGTHEAHLAVEEAAALARAFNGRVRVVWAIGSPTMERSLVELQ----ADGT-LATGVLMDDDIGNALELEAERWQADTIVVGSQGKHGLARLLLGSVAERTTRLSHRTVVVVRAR +> +AGPSRILVPVDLKDGSRSVVDYALQLARPFGATVDVLHAWEPPQYATLEALLRKVDGTAPV-ALSHRVVIGEAGNVVLEEAERGKYDLIVMGTHQRKGLTRMLLGSVAQKVVGRAACPVLTLHVS +> +MPMKKILLGADGSDHSKHAARYAVDLAKAFGKVL-IVTTYRGQTITRRQSWYQ----KNDV-P-ESHILDGPAAEAIADTAQRRNADIIIIGSRGRSNLVGMIVGSTTNALMHIADCPVLAIRLK +> +ETTKPVIVPIDFSGMSVDAIKTALRLAA-DPKSVHVLHVVPVLDQGSHFREFLAEHGFTHL-R--EIILQGQPGEEIAEYAAKVEAGVIVIPSHGYHGVKRLLLGSVAEKVVRLATCPVFILRRD +> +NKSSLVVVPIDFSDNTPAVLEKALLLAG-SPDDLRCIHILPNQAGSDYFKEHYQEYNISPS-Q--FEVRLGSAGFAIADYAEEINARLIVIASHGHHGLPKLLLGSVTERVIREAHCDVYVIRCP +> +MATETWLVAHDFSPCGDAAAKEGARVVERLGGKLVLLHVHPLPQL-ERLQGVAR----YPK-VEDVVPA-RDPARGIVEEAARLGVAHVVVGTHGRKGLEHLVLGSVAEKVAKEAAVPVTVVRQT +> +MTSENTVVPIDFSDLSYAALDRALEISS-GTGKVHVIHVLSALSTEDHLKNKLTGEKYRDV-Q--IHVTIGDAGREIANFAQKVAAELVVLSSQGQGFLEHLLVGSVAERVVKLATCPVLVLRA- +> +-------VGYDGSAEAQHALHVAIALAADLHGDAHVLLVVRPPAHEA-LSRGLQ-TQHRWE-VS---VYADDPALAIAGYAEEHGFDLVVVGGHGREQMTHRGIGQSLEALLRHHPCPVLVV--- +> +-MSQPVLYATDLENGSDVVFRIALQ--MLSDAR-YFLHVFEETR-LLMQQRIQHILEPFDQ--I-ELVSFGSASQKIVEVAKNKDVSMIIMGDRRVNALSRFFLGSTAQRVIHNAGVPVLIVPI- +> +TQVKNILVPIDFSTSSYQVFELGHCLAKHNGAN-HLIHVIDPVYER---ENAKEELRVPHS--I-IALIEGIPHKEILSYSRQNDIDMIVIASHGWTNLSHMLMGSIADKIMRQSDVPVICVKS- +> +-MLNHILIPLDQSELAETALEYASKLVVIVPPD-SFAALYNP--PQ----DYLRRVG-KGV----DLVQVGQDAETIVENAANLNVDGIVMATHGRSGISRWLLGSVTQKVLGAAHCPVIVIPN- +> +FGFDRILVATDFSPNSVRAVRYSVQLAKRLGAR-TILHVVPEPAS------AAKRLDREYA-KD-CQRTAFSPRDEVVKVATELPADLLVLSTHGLTGWKHFLFGSYAEKILEHAPCPTAIVK-- +> +KQFKKILFATDFSTNAEYAFDVAVTLATKLRAK-IMVHVVPKPDRQ-KREATAAMN-NAEN--F-EKILFGSPYEEIMKKADEEKVSLIVLGKHGHRETEHFFFGTTADRVVKMATQPVMVVRH- +> +LQIQRLLIPVDFSNSSRRAFYTGIRFSRIFDAE-HILHVPDSIAD---ETGVRRRINKGGI-AV-KSILGGKPHAEIVKFACSNDVDLIVMGADGGSGVKARVMGTVTERVVRDSPCPVLCVKP- +> +PKIKKILYATDLSETAKYAFGYAADMAENYNAL-TIIYVMENMPI-YLKQKIKARLECRLL--VEDKITRGNPAEEILDISKEISADMIIMGNHGHNIL-DAVLGGSARTVVKNSEIPVLVIRL- +> +PQIKKILYATDLSDTAKYAFGYAADMAKHYDAM-TIVYVMESMTI-YLKQKIKSKIECRLL--VEERIPKGNPAEEILNASKEIHADMIVMGNYGHNIL-EALIGGSARTVVKNSEVPVLLIRV- +> +FEVKRIVVPLSLCSHSELAFHLAHDLAERYDSE-CAIHVF-----ELYDKIFRQRIDGRCT--T-RIVTHGPYAEEIVREARDIKAHLIVMGTHSGKTLQQNLLGSTMTRVLKQTPCPVLAIRY- +> +NTFGSILVPVDLGGS--RILRTAGELAEAMDAS-SVLHVVQPML-YTIEDRARSAME--GE--A-AQVRTGTVGTSILDECRSGDYDLVIMDSG-EDHLLTKLFGSVTDKVVKNAPVPVLVLRG- +> +-MFSRILLATDFSEHSEQAYPWAAQLAASNGGT-VLVNVLEGDVN--FEKAAQTALDALGA--TH-LVQGKRASETLVQAAEDLDCGVIVISTHGRGGLAKFLLGSTAEKVVRTAQRPVFTIHL- +> +IKINKILVPVDFSEGSALALRYAATFASEYGAQ-HLLNVIEEEMA-QNHKRLEEFVPD--F--I-IKVKGGLVHECIIEYARENEVSLIIIGAHGQTGFIDSWLGGNSYEIARKSPCAVLTVKP- +> +LKVLRILVPVDFSKESDLALEWAVMVARKTSAT-YALHVLPLPEK----------VEKIPG--S-MILEKGRTPDVVTRICEQKDIDLVVMTTRGRRGLKHFLPESTTEDTVRRAPCPVLVLHL- +> +KNVKNIIMPTDFSRLSLSAFELVKQISELINAE-HIIHVAETNPIM---EQTREELERDET--I-KVLLTGLDFEEIVKYAAELHESLIVIATHGRTGLMHTLMGSVAEKVIRYAKCPVLVVPH- +> +LRIQKVLFPTDFTGASIHAASYALSLAEAYKAK-YVVHVVDTSERE-MESATEMLR-RFKG--L-ERVLDGEPYKEILKVINGSAIDVVVMGTFGKARIDRVLFGSTTERVMRKAACPVFVVPP- +> +--MKHILVTTDFSEEAGSAFDYAKEQFKLSGNEQTLLKIIDVVP--AYKQASEKIRQ-AGL-PTV-IKPKKSVYHEIIQFAKSSNVSLIVMSTHGRTGVKHFFLGSVAERVVRSSPCPVMIVPA- +> +GRFERILLPVDFSSDCDVVAHHAAWFATT-GGTVHLVHVIVNPDLL-LRAVA----EL-PA--VTRHVRHGDAYEKIRAVVQEIEPDLIVLSTHGRGGIAHLLIGSVAEKIVRHTPCPVFIVPR- +> +--MRHILFPVDFSTPCENLVPAVEAWAKRYEAD-TLLHVHELPVPL----ASHQRLNFAGL----RIQVDGRAGTAIVDYAKANGIDVIMLPTHGYTRFRQLMLGSVVASVLHDCELPVWTSAH- +> +TKPSRILLAIDGTQGSYRAAHHAALIANLTGAE-ILLHCADPHS-T----RLGPARDDSHV----MHTVEGPAAETILGMALRERCDLIVMGRHGTGDTEELPVGRTAEHVVRAAPCTVMVAA-- +> +IVIEKILFPVDLSESVNSFIPYVVTMTRKFNAT-YIATVTPDVSTE-QQGAAHHIK-RLEG--V-ECVLVGDPADQIIDLARQEEIDLIIMGTRGRSGLQKSIFGSVCDRVIRSAICPVFSISP- +> +LAPKTIMVPLTAERPARLALRAAGQMARELGCR-ILAYV-SP---I----RLEGALGFGDL----EVARVDDPGDGILALAREHGVDLIVLETRPRSLLERVFVPSVAAKVVHHAPCAVLVLPA- +> +SRGQLLIVGIDFSEGSAAALQRARQLARHLDGR-ELLHVSDAA-------EAGGFDA--------ENVRQGVPWVEIARRAAEAGATLLVVGTHGRSGYQPLAIGATALKLTLTAPCPVTLVNA- +> +MIYQRVLVPVSGKNSGERAAKALRHAKTLCSGE-ILLHVTEA---K----TLLSPLV-EGV----RLVREGLVADTIVTVGHEEGVDMIVMYTDGRDGLADMLVGSITERVLRNTDIPLLAVRR- +> +---MKVLVATDGSERAMKAVRKSLEMAEKEGAD-TLLSVGYFLSV-ALDADSRTALEEKGI-KT-TMEKGLVPANVILEVAREGRFDHILLGSTGKTGLEKYLIGTTATKVVANAPCTVTVLR-- +> +-MTLRILVPIESLDDTHPALETARRFFPGA--E-HLLHVVIPGIL-----ESVAQVDTLGG-----LIQMGDPATEILHRARSGDFGLIVMATSGKRGLQRLLVGSVAQRVIRESPIPVLSVRQ- +> +VGYDALHLNNSEQSVGKKALEVACKFAKENNAN-CIMASLEQRN-E----KVKNHLDFESL--T-LSVNYFTPGEDLVNFAKDNGIDLLFVGVRNRSKVSKIMFGSNAQHIILNSPCPVVTVR-- +> +-------------------MELACRLGAEQGAT-MLAYVI-----EQTAGAALGRAE--GL--Q-RVARARVAGEEIVRLARESAADLIVMGIRPRIGLRDEILGRTSDTVLRRAPCEVLLDKL- +> +KDFEEVVVAVDGSDASIRAARVALRLARDLDAPLVLLHVFPMMSARQAFSDVRKELGEAEV-EIREEARIGDVGEEIIDYLGDAPDRMLVMGRRGQNAMSALLLGSVSDKVIRHSRSPVTVVG-- +> +MVFKRILLPINKIDMPVNIIKKTIQLAKQLKIKIKAVYVHNTTKAYAVLKEIKKMGEKENI-DIQTILIEGIPEKEVIN--EAKKNDLIILNDEGTTTLDRIFSSSFSEKILHNVPSAVLLVK-- +> +---MRILVPVDGSDASLNALRYALGLRDVHKEGIHI-EVLNVQQGEEALIAAKAMVDEAQA-DYDVSIVVGGVAEAIVEQAHEKACDAIVMGRSGLEGVAELLLGSTTNKVLQPQISPLRLFPD- +> +-MYSDILVPTDGSDSIEQVLEHTIDIADGRNVTVHALYVVDDREGRAATADVEAALEEAGI-SVTKTILRGRPADHIVAYVEDAGIDLVTMGSQAGEYE-QNMLGSTSQKVVTQSPAPVLTVDV- +> +-MYRKILVAYNGTPESRCALHACIRLAPGPEVEVHLLGVINLALLEQELTKGHKLLSDVGL-KVITHFESGEPINVIGDLVTQLGIDLVIIAHSRKKPMARWWRGSTDSLLVEKISCSILVASD- +> +-SLDNILVPHDTRKESVAAAGHAFRIAQMAGSTVHGLYAVESSQGDAALTQMADRAESRGV-PFVR-IRTESVAEAILDYADEHDIDMIVMGKGRQKIDGPSNIGGNLLHVLQWTDIPVLTVCNP +> +-MFDSILVVTNGTDPGSRPAERAVALAETHDAELHA-LYVVDVAAVEF---VANRGAERDV-P-VVKFRYGRTHEEIVDYAAAHEVDLVVVPSTTRRGLSRMLPTDLAERVIGRTDVPVLGIDVA +> +-AYHCIIVPFDGSDHAQSALNAACGIAKGHDTQVHVVNVVPINIHAEMVNTIGDASELDPS-QVTYEIAHPSAVDGIIDYASDHSCDLIVMGRRGLGAIRGLL-GSVSYGVIRATTTPVLTVK-- +> +-DYQTILFPTDGSDSSNRAIEYGLDRIVEPETVVHV-LYVVRPVAIEEFVDRVQRKDETGI-E-IEHIRHGIIPEEIVQYAADQDVELIVMGRSGHTVLDRFTLGSVTERVLRAIGTPVLVI--- +> +-MYDRILLSTEGTVASEEAETHALELAAAHNAVLHVLYVVDEDHGEQTLSELRHRAAETDV-DVEMSMQHGRPAETIVNHADNCDADLLVLGTKRRPDEYRALLGSVTDRVLRLTTRPATVVKTE +> +-IYNHILVPYDGSDLSQKALFTALDYINY-DPKITVLNVEE-S-SEELIKDIEQTGPIDG---RFNVQMTGKPDQVICEYVDSHNVDLIIMGCRGLGAVRAAF-GSVSTAVLRGANCPIFIIK-- +> +-MYDRVLVPTGVGDDAERTINCALDVAQRYDAELHVLRVSDPEKRPEISNRVGERAVAGGV-NVVS-VRCGPPVETIREYADESE-DLVLLPDRGGFCDESYRVGGVVGRCLRECSISVMTVRAE +> +-MYERLLLPVGEKASPDDRYEPVFDLAREHGATIVVLSVADTNEATDAAERFADRAREHSV-RVET-VVQGTPHEEVVAYADAREIDLIVMRKRERGRLQEALLGSVTDRVIRLTDTPVLVL--- +> +-NRGEILVAYDGSDSSRRAVEFAAERAGKTGEAVDIVYVGGDR--DEFLRERIV-ANFETI-Q--MNTGNEAIARRLAEYIRDHEYTLLVMGNSERGRLYNAVRGSVTGELIEQRPLPILLVPAA +> +-MFKHILVGFDGSESSRRGFGTALEMAVRLGGALTVMQVLATYAAQREVAALTDAAEARGV-PCRTVEFAAEPHQALLLQAQRDACDLIVLGGGRDERGGRVPPGRETASTLVRGSIPVLVVG-- +> +-MFRSILVPVDGSGLSNKPVQTAIAIAKMHTATLVFLSVAEPRAARANVQKAVNASTDAHV-PCEAVTMSRIPCEEILETAARYQCDLIVMATRGMGVIDTVFKESTTQQLLTKAEIPVLVLP-- +> +-MYRHILVPLDGSELTTSLVAQAVEFALGLGARITFFTMVEDYRASTVISKAVAVGQAAEL-ACEGVRIGTDAYEEILQVAKEKECDLIYMASHGRRGLKALALGSQTHKVLTHSHLPVFVAI-- +> +-MFTHILLPTDGSEQCRKAIDGALKLARATGCRLTAYTCIEEFYAKDCIDRIAERAQEEGI-QFDSDSQFSEPYLGILDAAKRHACDVIFMASHGRSLMGRLLIGNETRKVLTYAQVPVVVYR-- +> +-MFKNILVPIVDDMVTPKSMKMIADLVEQDGAALTLAYVSDPRHANELLAKAAKMI-GKNV-SLKTLEYNATVYEGILAAAKKAKADVIMMASHKRTGLKGVFMGSDTHAVIVHSKLPVVVCI-- +> +-MFKNILIPVVDDMVTAKNMKVITDLVKADGANVTLVYISDPRHAKEILEKALKLV-GKEV-KAKVHEFSATVYEGILESAKKAKADAIMMASHKRTGLKGVFMGSDTHAVIVHSKLPVVVV--- +> +-MFSSILWPVDGTPLSFTPMQTIINLAKLSNATVAVLSIAEPRSARREVDKARAAVVQAGV-VCYDLALSALPSAEILHTAEQRGCDLIVMATRGMGVVDTLFTTSCTQEVIEASKVPVLVLP-- +> +-MFRHILVPTDGSDQAQAAVVRAIEIAKEISAQITVLTVSEPFNAATVLGRAKVAASAANV-NCSTILQHDSVYRAIIETADQRGCDLIVMTWPRRHTMLSHWHESKTVRVLKYCTVPVLVL--- +> +-GSMKVLVCTDGSELSEKAIEAAVGVALPLKAELIGMTAVKGVEVQKRLSVIYEAAKAAQL-PCRVMIHGEAPWQCIIKLAKDEDVDYVVMASRGMGSIGSLFIGSETQKTLAQIDRPVLVVR-- +> +-LKDVVQVCTDGSDLSHKGIESAVEIAKALHLPVVGMTAVLSKAVQERLAAVKNLAEAAEI-PYELVEHCESVADGILNVADRHDARFIVMASRGLGTLGSLILGSETQKVLAQADRPVLVIR-- +> +--MSKLLVPINDSNDIECALKHVIER----QGTLFLLNVQTPINGMQILQPMIDGLDAAGV-PHQERVVVGHKAESIVQFAREHHCDQIVVPKHK-SVFENLGLGSVGSQLRQLIGAEGICDI-- +> +-SQTDVIVPLDESVASESILPFVGDFVRAWGAGDTRIILTNVCNAQQYLDKIKVNLTEQGQ-NV---VLIG-PAEEIVNLASNNPFSIIVMSTHGQSGKDKWVYGSTTERVIVGAPCPVLLLKPK +> +--MKNILVAIDFSNATDAVIHQIGKLACPNDSIIHLLHIVEPSIAKNHLQKTAEKLSRLDA-TIIQAVEDEFESEAVINYAEKHHIDMIVVGKHNHGFLSTVFLGSVASSVMRKSPVPVLVVPVT +> +-MSERILMPLDGSQLGEAAISYIDGLISRLTVEITLFHVVTNVEAMAYLERVSSRLKKEKI-GVACKVAANNPAEAILEAKDEVKATLIAMATHGRGGITRFAIGSVADKVMRSSEVPVLMVRSS +> +-MYKKILVPLDGSERAEAVIPHVENLVKHDETKVIFAQVVESGQVKQYLASWKDQFRAKDL-SAKILLLRG-AVEAILHAGEITQAELLAMSSHGRTGLARMFHGSVAYGGSTESDALSCWFAQK +> +-MFEKVLVCLDGSALAEQILSYIAGDSRSFKKII-LLKVIAAPETPDYLESRAQPFREIGL-DVECVVLEG-PTKAIIDYAHDSDVGLIAIATHGHSGLRHITMGSTAEYILKHAGLPVLMVTPK +> +-MYTKILVPLDGSEFDEHVLPYVKWFVKVSEVEIIFLRVVEPLLAEDYLVKLAGQFRRGQL-KIKTAAVIG-PARAIAEYVGHSRADLIIMATHGFSGLHRLVSGSVAAELLHNATVPLFLVTPR +> +-MYQKTMVPLDGSELAEYVLPHIAAITEGGVREVIFIRVVKPFAADGYLDRLVIRVSYDKT-KISQTTILGEATGSLVDYATNNKVDLIAIATHGRSGLSRWIWGSTADRILRHTRVPIMMVRVP +> +-MYKRVMVPLDGSELSESIIPQVVSVVKPSNATVVLFQAHEAIDAQSYLDKIAGDLANQGI-NSEIVLGKGRPAEAIIQYATTHAIDLIIMATHGRSGISRWAFGSVAEKVFRQSPVPILLGPVA +> +-MYRKIMVVTFGTELSNKAVKEAARLAHSVGAKLLILHVRSPLQERKLLEGAVGIAASFGV-EAETAFIADAAHEAIVRVCQEQQCDLIVMATRIHRAIPGFLVQSQTQKVLAKTSTPVLVVR-- +> +-RYEKILVPLDGSRQAEYILPQLEAMVKAFDADVTLLHVVADKDITGYMEHIAEALRGKKV-RCEWQLTHG-PAEEIAKFAATDMADLIIMTTHGQGTTKKVRTGSVAMEIISSNQIPVMLVRPP +> +-MYRKILIPLDGSVEAEGVLPMVRGLVTP-ESEVILFQVVSAGEAIRYLRQVLGKLGEPEG-QW---AVFA-AADGIVDYARSEEVDLIAMCSQDRKGLSKLMKGSIAEKVRKKTATEVQVFKPG +> +-MYTRILVPLDGSPIAEQALVHAAQMAEIFDAELILLRAAFLAESEDYLDNVARRLRGHGR-RVQTEVRWSEATEAITAYAVAQAVSVVVMATHGHSGFEQWPMGSIAEKVLRSMQVPVLLIRPS +> +NKVQKILVPLDGSKFSIRALNYAINLAKFTHSKIIGIFVIPSDLGHKILEQAENRCIQNKT-PFTKIMSSGNPSIVIVKYTERNNIGLIIMGSRGRGHAGEILLGSVSYNVIHKSKKPIMIIK-- +> +SMFSHILIGVDGSKESFRALSYAMTLAKQFNGTCDVMYSIPPREENHIRDLVQDIAAKEGL-TIGFHTRVGDPVDAMIEYVSTSGVDLIVVGSSGKGMADRLILGSVSTGIVHKSPVPVLVTKP- +> +NDRKKVLLCVDGSENALRAVEFARDLLAPLDAYFTLLVVVTPMIGRAKSRAASSLLEEAGM-DHCLSALTGNPAEVILKLSG--KHSLVVMGRKGSGSLQSISLGGVAGQVSQNIKVPLLLVP-- +> +ESITALLVPVDGSEGSARGARYASELAELAGATVTLLHIIPAAAQRGPFAVACDAMGRELG-EVDHRIAYGEAASAIMRTAREVGADLIVLGSRGLTPEEDAWTRSLSRRLLSQATCPVLVIPN- +> +DMPEVLLVPVDGSKNASAAAAYAARMAEKLGVPVQLLFAFPETYSPGGFKLRDEAMGDSSV-SVEEKIITGEAAAAILDHSGSVKGGMIVMGRRGLSRVEEILMGSTTQRVLHHAKCPVLVVH-- +> +NVEGPILLATHGTENAVRAEDEAFELSRRLGLPVTALYVVHEN--ADWTRTFIRKGRGAGI-EVRRVIRIGEPGQAICDEAREMKAGLIVMGGRALKRSKEFKARIRMDRFLREAPCPVMVIP-- +> +PMYKKILFCADLYAGSDYAFAAALDLAERSDAELIVFHVLESRYAEKRI--------ENPE-FVRIEVRAGVPWMEIVRFARKEKVDLIVMGSYTIHDLEKPHLGENAQKVSLRAPCPVSIITS- +> +TVFRRLLVPVDFSACSLQAARHACAMTRMVGGSLILLHVLDGRA-------LLGNEARHPP-QLRVVSVASDVALTILDVAHSERADLLILGTHGRNDLGSGVLGQVAHRLVLAADLPVHLVPE- +> +MEISLILVPIDFSDCAANALSYGKKIASSWKAELLLIHVVDSVSSEDTFRHFLNDLGRDGL-IKDTIVSYGSPFQEIAIKARELQTDLILMGGYGSRGIDEIFFGGTVDKVVRLLPCPVLCVPM- +> +KRISAILVPTDYSNCTGEAISWAVALAAPLSADLLLLHVIRRED-EIMFRTWMTDEGEISL-LRETLVTVGEPVEKIVTTAFERQVDLIVIPTYGRKDPEEGI--SVSDRVVRMATCPVMTIQA- +> +KPYQQILVPVDFTKISNTIVARANELANFYQAKLTLLNVLEDAG-PAKLRKLADNLGAANV-ALEVTYASGKPSDAIIEFVKQNGIELVVVGNSGKKS-VLGFMGSTAEATLKGVPCDVMAVRI- +> +-MLQKVLVPLDESSFAEQAIPFAQRLLAPEGKLIIMTVVEENNHATEYLKQLGAVLRKDTTHQVEAEIRVGAPSVCIVEAAQDYEVDAIVMSTRGQSDFNRLLIGSVTQKVLNDAQCPVVVVPA- +> +-MTQSILVPLDGSRSARRALEHACLMQQARGGALHLLHIVEPPHGMALLKETWAAVGDPDVHFHVEDNPQGRPDRTIVEMAQTLEVEAIVMGSRGLSDMKGLMVGSVSHKVSHVAHCTVITLHV- +> +---KTILFASDFSNLTDRAQSYALDLARATGA-VTLIHSVEPIDARSKSQSVVAAFEEAEI-ACDVRVEVGKRWKAIVDAASSGDYDLVVLGSHKINDGDKVYLGTTTHKVFFATEVPLLVVP-- +> +---PHNLLATDGSESAQRAAEVAAHLAQVLRG-LSIVTVEGGIFATRVLCQARDIATKTGT-AVEARTSWGDPAEVILEMASRGNVDAIVVGRRGRGRLACAFCLAVVRRSW------------- +> +-----------------------MRHAAYYAQRVSLFHVELPIMSAAALLPAEEVLRAAGL-AFDSQHVVGDPADQIAAAVQRLQPDLLIMGTHGHSALKGFVMGSVTTKVIAATSVPVLLVR-- +> +-MLQHILVTTDGTALCNSALDQARELALRLDCHLTILHVIPDLACQNIIQSALQRAAGTQA-D----GIVRTIAQVIVEEADALNVDLIVMSTHCRTGISRLLTGSVAETVLHHARQPVLLTHEP +> +-MYRHLTVALDGSHNARPALIEAVRLAAAAKARLSLVHVISV-QGQFILDEGREYAQQHGV-GVSAHLLEADAATVLVDFAAGAASDLLILGTHGHRGWKHLLLGSFAEAVLRRTTLPLLVVRNP +> +-MNSRILVSLDSSAASLRGLDEAIGLAARDGSALRLVHVVNASAGEQVLQQGRECAQAAGI-AAGTLPFTAHVADIDAEQAGAWGAGLIVAGAQGNCRFGRALQ--------SRTSIPAPLVRAG +> +-NYKNILVALDDSEITDLVLQEVLKFKEHQNSNIRLIHIIDATEGQKLLDRAKEICHHMKI-NVDQKVVEGRIAEAIVKEAQEWPADLLVMGTHGRRGFSHLLLGSVAENTIRLATMPMLLVPAH +> +-MYNRVLVPIDGSETSMAALREAIRIGQCQQVGTQIRLLYVI-YGQDILDQAKQEIESAGL-RVETRLVEDRIPQVIADEAKAMPAELLVMGTHGRRGLNYLLLGSVAEGVMRLTLCPVLLVRSS +> +-MYTHIVVTTEGSHIDHAAVRHAAGLTRALGARLTLLHIVPDAEGERALAEGTVDAACSRL-S----AVQRSVARAIIEECAALGGDLLVMATHGRSGWQRLMQGSVAEDVVHHAHMPVLLVHQG +> +-MFRRLLVPVDGTPVALEAVDAAIAIARIGKADIHLLHVIPSFRALAWLGEAREHALGAGV-A----CEGPRIHEAIVDVARDYGCDLIVMAAPLRSGMVSGLFTREAQAVMQASAIPVLAWR-- +> +--MIKILVPVDGTECALNALRHAAFLAREGGRSEVVLLNVQAPLGESALATACELEAGV-----STLIGLGHTARTIVSAAEDNSCDSIVMGASLWSQIKAAVGGGLPAQVIRRASVPVTVVK-- +> +--PEGILVPVDFSKHSEAALIFAMNIAELMERQVIVLHIVHEPAAEMMEKFIEEATC--D-FKAETKFLDGIPSRRIVEYAKKIDAHMVVMGSHGHRGLKSVLIASKARKVMQYAPMPVTVVK-- +> +--NEKILVGWDGSEKSRNALRYAIDEAKDKGLKITAVHVEKGESRSKIGSLLKEAIG--GMKEARVIKHGYGPAVDIVKFAEKNSFKHIIIGSHGRSGISRIALGSVARGIVEKAHCIVTVVR-- +> +--KEKILVGWDGSDQSRNALRYAIDEAKEKGLEIAAVYVEKEESEVKINKLLEEAIG--GLTETHLLKNAHGPAVDIVKFAEKNDFKHIIVGSHGRSGISRIALGSVAEKIVEKGHCIVTVVR-- +> +--FKKYYAQQIFSAESKEAIRYAVKMGNQSQTVIHLIHTLEAPIMNNLLAELREKGY--GV-----VKDNADSAESIVEFAKSIEAEAIIMSSHGRRGIKRLLMGSVTESVMRLSDIPVVIIR-- +> +--KKIFLVAVGFSEKPEDVLEKAVEVARKYKAKVYTIHVIAEMPMDLLKRYIGKMDY--E-----PIIEVGDPGIKILEKAEELDVDLIIMGHHVRTGLTHILHQNSCERVVRHSKKPVLMFN-- +> +--TPSIVVACDGSEHSLHAARMAAELAQATGQTLKLLAVFPGTKEEEAKSYGREVAAKKNGMPAEEVLLKGDPAKEIIEYMENNPGTHLFLGRRGHSLVRSLTLGSISEKVVRHASGPVTVVS-- +> +--ARSILVAMDDSPLGRRALAYALET--FPDAHLVAAHVAYLE-AQRVFEAIKE-----DG-AVTVSFLTGEPEERLVEYVDSAGFDGVVMGTHGRDGVARLFIGSVAEAVVRKTDVPTTLVK-- +> +--FEHVLVPVDGSEAARRAAEHAIDLVSDTGGRVTALYVIDM--RKKGEELTAEILA--GVDETAV--VTGIADEAIVAYAEDNDVDLIAMGKHGKRDPDKPLVGNTARRVVQESSVPVHTV--- +> +--MDKILCAIDGSKAAQRAVDFGVALAKKNKADLRFVTVSTVSQEALIEKELSEAHA--DLQASCVTIRGRDVATAIVGYALQEGFDHIVMGSTGHTAFGRLLTGSVVDDILKTQHPPVTVV--- +> +--TRRVLVPVDEFLQAKKSLAYILSE--HPCAEVTVLHVIDSAEVTSLITDVQR-----GV-RLSTTTKIGRPSQTIVDYAEQHHIDQIVIDGHGHSSTDYVSPESVAETVDCRSPVLVTII--- +> +--APHVLVPYDDPELAAAALEHALTE--FSTGEITVLHVFEPADDDSILSRARK-----DR-TLLTARTAGDRPNAVHEYAAEHDIDHIVVGGREQDGESQFLEQQLADDVASGSPVPVTIV--- +> +--VTQVLVPSDGSDCAARGVERALER--FPDAQVTVLRVVAPVDPGGAVAR--C-----EV-DVRTVVEPGVPASTIVEYARANDVDAIVMGSNDRSSLGRLLLGTVSGTVAENAPVPVELVT-- +> +---MEVLVPINSRDSARETVEYALRE--YPDASITVIHVTPRNGTDQLFEMANG-----GR-LLTTITAVGCPVREIVAYAEKSDTDHIVIGNCKRTGLARFLFDNVTKGVVYRSPVSVTVVK-- +> +--PQHVLVPLDGSDRSFAGLEYSLASF--PDATLTALFVVDPTRGERVLDRAVDREVGR-----RTLLRTGTPHTEILAAASESNIDHLVLGSHGESPITRPFLGHVSDCLLYTSLSGL------ +> +---MDVLVPVDDSDCSFRALGFGADMAARYDADLHVVHFADEESTDAVVERAQRVARDASTNIDVDVRSGGRAGSEILDLVDERGYDHVVMGHHGAGTIERAILGSAAETVLRSEKVPVTVIP-- +> +---MDVLVPIDGSDGSFRALVFAAEFVRKFDATLHVVHFSDEATTDEILSRARDVSADISTD-RLEFRPAERVGENVLELVTENGYEHVIMSHHGSGTVDRAILGSAAEKIVRSEAVPVTIVP-- +> +--MKKVLVAVDGSAPSEKALEYALEDSKKLDSQLTILRVVISLPEEYLEELKDKA----GGVANTKVLTGSNAAAEIVRFAKEEDYNEIVVGGRGKLGLRPSP---------------------- +> +--------------------MEGIELAKKIGAEVVCVYVAKENAAEQFMQPLRESAEAGNV-KFTSETFISTTAGYIVYAAEKNGCDLIYMASRGYTGWENFFMGGVASKVLAASQIPVLVYKV- +> +-MFSHLLVPVDGTGLSWRGVLVSLELARKLEARVTGFVVMPPLHAREILADFAAEAAKAGV-SFEGRAERTSVDGAIVEAVEKYGCDLIVMVTQGRGSFGEMLFGSHTKNVMARCTTPLLVLR-- +> +-MFKHIFVPVDGSELSVRAMDASLELALKLGARVTGFVCEPDIHAHAVLDSFAQRARECGV-PFESEYRRSQTDATIAEVADLVQADLILMVTHGRGLFGEMLFGSHTKNVMSRTKVAMLVLH-- +> +-MYRRILVALDGGAAAEASLEQAILIAQASDAEVEVIFVLDISAAEGVLAAAAT--KRARV-RFTTCLIQQGIAETIAAEADAWSADLIAMGNNGNHGPSGPRMGEIVRKVMARTRQPLLLARA- +> +SLYHRIIVPMDDSLAAHAGLRAAIDLAQDQQAALKIIAVVDEAGARQLLQEAEQ--RAAGL-SPESELPDGHVARHIGAAATAWQADLIVLGTHGRHGFSRWLLGSTTENLLRGLAIALHIVPC- +> +-MFTRVMVGIDGSRAAVAALAEAIRLAAAEKAAIRAVSVVER-VAQAALARAHD--LLTGL-TGETALGESDVASVLLRESHAWGADLMVLGTHARHGIERVLLGSTAGPFLRMSTIPVLLIPH- +> +LEIKRILFPIDFTENSSKILPYVLSVSEKYDGMIYLLHVVEDLGAEKRMDKVCDEQL-KSCPNFQRMIVSGDPAQEILKTIESEGIDLVVIGTHGRKGLEHVFFGSVAENVVKKSPVPVLTINPY +> +PSFKNILYCTMIGPNSPYIFKHALALAELSGGKIHIIHVMEALEAKERLIALCPPKN-GD-MIASISIVAGKPTEQILKKSDEVNADVIVMGATSTHSLFEKVVGYTAQNIVSNSKVPVLTVQVP +> +IEIKKILFPLDLTENSSKILPYVLSISEKYNSTIYLLHVVQDLSAKKAMDIICEKQL-QSCPNFQKSVVSGDAVNEILEIIESENIDLLIMGTHGRKGLEHVIFGSVAENVVKKSPVPVLLINPY +> +PEVKKILFPLEFAKISPAVVPWVEFYAQQFNAELHVLHVVPYSKAEQSVGHFINEHF-AK-SSVVTKCVSGDPANEIVKYAEAQGIDLIIVGTHGKHGLDRSLYGSVVDLVLRYAKMPVLCFNPA +> +VSIKKIAFCTDFSENANQAFDLAFDLTRKYQAQLLLVHVVPPLRAKEQMESNYLQKI-GD--NALVRVLSGHPASEILNFVEQEKVNLVVMGTHGFTGLAHFFLGSTAEKVVRRANCSVLTVHKA +> +PEIKKILVPLDFSGNSIMLIKKASKVAKELGAELEIVHVVESLYAEKKMESFLAENL-SD-PHQAKIITGNDAAAEIIRHAEENNCDLIIIATQGFKGLPKFLFGSVAERVLKQAHCPVMTVKPR +> +IEIKTIAIPVDFSEATPIIVEWGKALAKKLGAQIILINVIEEIGAREYMQSLLNKHF-SD-PNVKPIIVKGKIVEKIIEVAKENKADLIVMGTHGKKGLDKIIFGSVAEGIVKYSPIPVVTINPY +> +PSIKNILVPVDVMEDNGFFVEYAKMMAEKHEAKVTLLYARPPLRAIDELDKLAENQL-QN-TDVSIKLRRGQPQDLILEMTETGDYDMVIMGTHCRKGMERVLFGSVANRVVKHSNTPVLTIHPA +> +VVFKHILFPTDFGTGCTREAAFAFSIGQEHDATLTLLRVVRHL-VKRQLRDLVPSGA-EA-CETNFRLAAGDPAGEILHFVEKTKADLMVMSK-GADWLAGHVPGTTAYKVVSKAHSPVLTVRS- +> +NKTMKILVALQFTESPDEILDRALSVAKKYEAEIYTIHVIEEMETLKEMTSYIGKLS-DQ-KKIEPIIVVGSACDKILETAEKIGADLIIIGHHVRKGVTHMIHNNIAEKIIRNAEIPVLTFNIR +> +---MKIAVAIDGSDHSIRAAEYALTLLENTDGELEVISVTDYNYQDRLVRPVVEMAEEAGV-KTTVKLLRGKPDVEIIKHLQTEEVEQLVLGSRGMNLMQEMALGSVSRSVMEQANCPVTIVK-- +> +---MKIAVAIDGSEHAFRAAKYALTLLKDADAELEVISVTDYNYQDRIVRPVVELADKVGV-KTSITLLRGKPDLEIIKYLQTANVEQLVLGSRGMNIMQEVVLGSVSRSVMEQANCPVTIVK-- +> +-AFQKILVALDC-LEAATVFQEALKLAKT-GSKLMLFHCISWEKVRHSLQAYRDQAISQGV-SVEYKYQVGNPSGSICEQAEDWGADLVMIGRRNRFKWSELFSRRVSSYVLNNASCSVFMIQT- +> +-MLKKIMVAIDE-AASEWAFDLALEMAKA-NAELTLIHVLDVYRYEALLKKYQGKAKSAGV-SAQYKQPYGHPGPTLVKTVKEDGIDLMVVGNHDPSTTESSVLGSVSNYLVHHSPCSVTVVHP- +> +-NFKRILVAINH-PLTSIVFDRALNLAQQ-QANLMILHCLVDFQAKVWLEEYCHQATARNI-STEYQHHFGEPGATISSIAQEWNADLIVLGRHDHSAIAEFFVGSVSNHVVDYANCSVLVIKD- +> +-SFQKIVLAIDD-KFSEYILKQGLEIAKI-QAELMLFRCIPHNTLE-KLKYRCEQATNHEL-NISYRYKIGEPGYSICETAQEWSASMIIIGRKGHSALVEALIGSVSNYVIHHAQCAVLVIEP- +> +-SYQKILAAIDLSAGKSSIFKKALTLAQQ-QAQLVLLHCSPLPLARQQLQDLRQQATAVNI-EAIPLLRFIDPSRGICDAVKDLGVDLVVVGRRGLSGISEILMGSVSSYVVHHVSCDVLIVQA- +> +-MLKKILVAIGDSAESQAILDAGLTLTEK-GAQMLILHVINPAMGIERLQAYAAQVKERGI-EVEVSQNFGDSGRMICELAKNWSAEVIVMGRNQKSMLSEIFLGSTSNYVLHHAPCSVMVIQL- +> +FSLKKILVPTDGQAHSVRACQYAVTLAKLTRAEIIGIHVMPSQEGAEHLKQIEKMCVRENV-RHHTLLLEGYPPEEILKTAQKENASLIVLGIRKRSRFERHF-GVTTSDKIINANCPVTIINTP +> +-MSFTYLVPYDASNNAKRALEWAINHGKLSGAHIRVVNIQPSFLFGECTEGVKALLDASGL-QTSMEMGIGDPKEVIVDLVKDDPIDLIVMGSRGTNPMFSGVLGSVSYAIINSGICPVTIIPQ- +> +-MNNLLVVPIDGSPSSMKALAFAIDNAKMYQDKIILLNVQAKYKGLEVMKEAINMLNGNNI-PFEVKIRIGIATIEITSEAKEQEARMIILGSRGNGPVVSAVLGSVTYGVLHLATCPVTIVPL- +> +-MQNIFLVPVDGSEQCLTAVDHAVEAALVSGYAIQLLNVQPRITSDRILYQAEARTK-GRV-EVVCKTRWGIPAEEICEEARGIAVKGIFLAPRKPN----KKLGSVTYKVLQKSTVPVTVIPV- +> +--MHKILVAIDGSEHSERAVRYLIGLIQDGGGHLVVQPLLPTRKSAEDSQKAEVLLKQEGI-AFALHTLQGDAASQIVACSRSLGCDSIILGSHGNGFLAGIFLGSVAAKVIQLSDLPITLVK-- +> +-MLKRILVPIDGTEHSWRALEYACELVSYTRGSLVIMTVVSGRMGDEVLDAAHAILSGKNI-DCTYLLENDNIAKSILRAVGEQECDGIVLGSRGMGVLEGLFRNSVSSVIAENANVPVTIVK-- +> +-APKSILVPVDFSERSLAGFKAAKHLARRFHSKVTLLFVDEWTANRELLRRYDENTRAAHP-GTTTKVIEGGAKEELRRLTREGLFDCVVMGTHGHGGLWRFLLGSVAHSTLYASEIPVLTVHAA +> +-MYDRLLFPSDGSEITSSVFKYTLEVASEHDAEVHIVNVADSTKGEQIVLETAKQAEGREI-SIVSNVLQGQPHELIVEYGEQFDIDLIVMPNHGKEDLERFLLGGVTERVINHSDIPILTVNPS +> +-MYEHILLPYDGSEGAAEILHHASEIAHWTNATIQLLYVADTTKGQTVVEKAAKTLDTLGV-TYNTDVVQGNPAVTIAEYAKRYDQNLIMMPTHAREGISRHLIGSVCEKVVRLSSVPVLTARMQ +> +-MYSTILLPVNGSGGSDELVNRTLNFAQRVGASVHVLHVVAAQRGRDAIARIHDHATALDI-ETTRVVREGVPHQVILDYAAEHGVELIVMGRHGRTGVEQVGLGSTTERVVALADAPVVAVPVT +> +----------MGGGPANAALRLAIRLTST-NTTLHVLVVEPETETDRILDAVREEVAEWGR-SARTVVRSGTPRDRILEYAADHDIELIVMGAHGHQSVKRVDLGRVTEAVVHAATVPVLVVRAS +> +NIYEKIVIGFDGSASSRLALQKACELGERFGSELNVVLVIEPLAANMIIEKAKKIAANYKIKNVNYMVKYGVPANEIMKTATDIKADLIVVGRKSKKGLEKVLLGSVSQSIVNLSKIDVLITPY- +> +---MKILIPVDGSKMTKNVIDKAEEIGKVFEAKLILMTVLDSALENML-EKLKEENSDYPY-EIETVLKTGMPYDEIVKLADEEDVDLIVMGNRGLGAFSRTLLGSVSNKVLNHSDSVLVVKTD- +> +-AVKKIVCTVDFADHSSLVASYAKEFAQKFDAEVLVLYVAPALGAEANMKKFVAANF-SGV-KASGRVATGYVSDKILEIVDEVKADMIIMGTHGRSGLAGFILGSVAEKIVKLSKVPVLTVHPQ +> +-TFSKILLPIDFTECSTAVLSHAKLMKEKFDADIYLLYAMPGSEAENAMENFINQHM-QGE-PKKAVVRIGEVVTETATYVDEEGIDLIITASHGCRTAENRIYGSIAEGISRESGCPVMIVHP- +> +-PPQRILVPVDVKEPMDESLFMASALTLEEKGNVELYNVITLTPIHT-LKDLTLPY--FET-KFDVAVGEGQVANEICRRAEQIAADFIIIPTHGRKGLTRFLMGSVAEQVIRYATCSVLSFCP- +> +-GQGPIVFPTDFSAASLAGLPWAKRLTRFMETQLHIYAAVEPQGAETRLQAVAAHLDGLDL-PVIPRILVGNPADEIIQYADEVAAAMIVIGAHGYSGVRHLILGSTTESTLQHAQCPVLCVKA- +> +-MFKKILYAVDIECGCYAALPYIMKLKASGTEEVILVHIYDERVTYKKLKEVESKLRTTGF-DTKIIVDTGTPCKKIVEIAKKENVSLLFLEHKKKRG----IVGRTTMTVLDNIECPVFIVKE- +> +PEIKKILYATDFSEEASHAFGFAATLAHHCKAKIVILHVIEELVAIQSRLEETQYPDTPFV-VEKIIVKTGHAVDQIIRHSEGDKCDLVVMGSRGQGVLADVTMGSTSRRVLRRCSKPVMIVRI- +> +MKFQRILIGIDESRYSENAAEYGFALARTYHAQVGLVHITEPVL-SGKLIENTIKRFGDDL-QITQFNEFGSTADTILECIAKFNADLVVLGTHSRTGLDRFFMGSVAEDVVRHSPVAVLVVPL- +> +MKISKILIGIDDSTYAHNAAAYGFDIAHTYKAAVGLVHIIEPAM-SSSLIDNIKKEYAGEL-EVTSFTDFNITADGILSCAKQFNADLIVLGTHSRTGLDRFLMGSVAENVVRHSTIPVLVVPF- +> +KKVNSILCAIDLSQHSAQVLEQCFRFVNQLGAERLVLHTCHSECKLEKLIQKQ---DPIQA-DISIRVIEGDPVDTILKTVETTETDLVILGTGGKTGINRFLLGSVAENVTRKSTTPVLIVRA- +> +-SLKHVVVAFDGTDDSKEALELGIRMSKKMDSNLSVIYIHKENHIMALENEAKQILDRHHV-QADVAVSYGEPSEGIVTYAKENNGDLIVVGSRDMSGLKKLIFGSVSEKVSQRASIPVLIAK-- +> +-TFHHIVVAYDGQDESSAALTKGIQLSKQLGTRLTVVHVYQAEHSDEVSSRIRMKLDENQA-TGDVEILSGSPADAILSFADEHAADLIIMGNSDSGGLKKLLFGGVSDKVHHQSNISVLIAK-- +> +MQVKRIMVCLDGSKNSLRGFDAAISFAKQSNATLVGIHSVTKFEVRGIIGTVEKKAEKSGI-SFEPVVIGTAAGTDLTTFAPKNKIDHIVIGSRGLSFPKEIFFGSTSTFILHKAKAPVTIVK-- +> +NRFKRILVALDGSANSRRGMNEAISLARQSESTITGIYVLPGGKAKKFMSNTKTSAARHGI-DFEEKILTSKDTVEIANFAKSGKFDIIVIGARGAGSPKSEFFGSVSNGILHSSRIPILVVK-- +> +MEIKKILVTFDGSKHSEKGLDIAISLVKESKRSIVGLFVKPHSIVRKTFQTLREKCEENDV-KFSTEIRTGDVKTTIEKMTDHMNIDMVIIGSRGRGSVKGALLGSVSKYVLDKSKIPVLIVK-- +> +SLIKHILVPFDLSDMSHRAFEFSLDLAKKYNARISVLTIMYSEQISTSFILLEDAAKKFSV-QLKSDVFSKNVADTILSFSTNRKVDLIVMGTRARSSPRRFMIGSVAMDVIQKASCPVILVK-- +> +PIFRKILIPFDDSKLSEKAFWYAVNLDMNHKTEILILSVFHSDNVKLKHNELKKVAEKYNI-ACNSYTISSSISESIISYIYSTRSDLVIMGTRGNSTGRKLMLGSVSLEISQHSPVPVLLVK-- +> +LNISRILVGIDGSEYSIRALEFSKNLAHKYNSQIIAFTAFNIPELKILLSNLTKKAIEEGI-NLKVFDTKLTPDLAMTEYAESEGVNHIVIGYRGRS-FENLLIGNIATSIVKISKCSVTIIK-- +> +RKIKKIVIPYDGSIYSKHAFDMALNLAQKYNSKLILLTCIEKIKILKETSKLELISKKKKI-STTTKFVTDSIVEQILSFTKSTKADMIVMGSHGRSGIDKLILGSIANGVVQRSKIPVLVVR-- +> +-------MPYDGSNYSNNAFQAALAIAIKFESKITIATCLFRPNAITELAKLQKIAVTKKI-SIEARMSCNSVVDTLTTFANANKVDLIVMGTRGRTGFKPLLLGSVSVGVSQYASCPILLVK-- +> +DEISRVVIPVDRSESSRIAVEQGSHLAKLLGVDVAIISVDASHEHENILDEYKKIVEQKEI-TTHAEIIVGDAAEEIIRYA--EDNDLIVMASHSKKGMERFLLGSVFEKVLQKVNCHVMVLKP- +> +-MIERILVGTEGSQAADNAVSTALRLARAADAEIRAVHARETPEGERVLEAVTERAGKVDV-PATTVIDDRPPAELLLAQAREWGADLLAIGAQGESGFERAIRGSVADQLIRGSPVPVLTVHQP +> +-PKRAILVATDFSKPGKLVVPYAFKFALALNLRLTILHVVKVPPGKLELGRIVRFANENGL-MADHKLLVGIPQDTILEVAHSPDVAFIAMGTHGKTGLDRLRLGSVAESTVRQAPCPVLTIGAS +> +-LFKHIVVGTDFSQQADVAVQEAVYLARQHEAKLSILHVIDERAVARTLFETFGEDSLNSV-DIKTIAMFGRPQYELSSYCQSNDVDLVVAGRRGDSPLKQVLLGSTAEKLMRQSPIPTLLVAHP +> +-NFTKIVCPTDFSKSSEYAMWYAHAFAKGMNASIHCVNVFDNGALKKKLDHVIKKAHLLGL-EADGEVRTGRPALEIVKVVEESDANLVVLATHGHTGLERVLFGSTCERIIRLSPVPVLSIKHP +> +-MIERILMPLDGSAASAHTLPYGLALASACHAELTLLHVVVDPMA-KWAGAALLAAQAAGI--GVR----NDDRPARAILAAAAAHDLTVLGSHSRLGLDRFFLGSATQEVLRRAEGPCLVVRLP +> +-SIRQILVGTDFSEPSINAVLHADALAQLCQANLTALFAQVLHDDRERFAALKS---EYQV-DFESRVERDVSRNALLRTAESVDADLIIVGTHGRTGMGRLALGSVAEGVVRDAPVSVLSVHYT +> +-MYDRITIAIDGSDEAKYAAKRGLELALTLNATVDALYVVPQKSLRAFLSEIEELASEIDY-PIVTALSEGKPAVQISKHASDQNTNLIIIGRQGITGLGKRFLGGVSEQVLYQSDVPVFVIPDT +> +-MFKNILVPLDGSALGEKALNVAIVIAKAFDAKITLLHNISITSFADYLKKVEGRLHDCGV-AQIEQVV-QGIPTSAIQLAARNGVDLIVMTTHARTGIARTILGSVADEVVHSVNIPVLLIAAQ +> +-MDGTILLPVDPDTDSTAATDCAIASARQTDATIRVLSVLEFHDLTAAVDAAAERIENAGI-PVVRDRCEGVPYQEIVSLAAQTDPGLIVMGTRGSTTADEPRVGSTTQRVLALSAVPVLAVPLD +> +---MRALCATDLSAASEATIENETCLDCLGRIGVRTIHLVTVVPGERGLDRYRAVIEAAGF-DVETHVVRGTPHRRLNEVARTVHADLAVVGSRGRSPLENRVVGSTARNLARTTVVPLLVNRVE +> +QQYHRILVAIDGSYEAELAFRKAVEVAKRNHGELYLIHVVDTRTAKQTMEQYVETAKKLGLENVEYSIEYGAPKVIIAHDMEQHDIDLIMIGATGLNAVERLLIGSVTEFVTRNAICDVLVVRTD +> +KKYTNVLVGIDGSEQSEMAFNKAVTITTQNDATLSLLSVINGEEMKKKLATYKQTAMDAGVKDVNIDVKIGNAKVELGSDYRDNDIDLIVVGATGLNFIGRMLVGSTAAYVIKEAPCDVIVVKTD +> +QQYKTIMVAVDGSSEAELAFKKAVNVAQRNEAKLLIAHVIDTRMAKQTLDDYATYAKEQECHNIKTVIEYGAPKPIIAKQLQEHEVDLIMLGATGLNAVERLFIGSVSEYVIRNAPCDVLVVRTD +> +DNYQRILVGLDGSTIAQQAFEEAVAVAKRNRAALFIASIVPDNEAEKRVHEATRYAEEHGVTKVVPIVRVADPRRALAETLVDYHIDLIMLGITGKGVIQRLLVGSVAQYVSRHATTNVMLVKQR +> +AMYNKILVPVDGSHNANLALDHALTLAEKFDSEVMIISAIDTRSAKRHVEAAADVAKQRGI-KYTTLVVKGDPKTLIANDLDEYDIDLIVMGKSGVDAITRITIGSTTAYVARHATHNLLIISDD +> +FPPKDIMVPLDGSKNAERALTTAIALAKENKARLHLVRVIDPNATENYLEDVAKRVKESGFTNFSTKLLQGNIKSTLARSYEEHKIDLIMIGATGMNAISQAVMGSITAYVVRHATVNVFVVKDE +> +TIYRRILVGVDGSNEAEEALKRGIQIAKK-GATLGIGFVADVRYGKGLVEIYKNEAEQLGVENVETFVKFGTPKTTFVKKIDKFEPDLVLVGSTGLTPTEQFILGSVSDYVAAHAPCDVIIVRGK +> +ADYKNILVCVYGEESSEDTFDQACAFALKEGAKLYITSVVDPKQASEQLQAFKQKAEEKGIAEVETILDVGTPKVRIASHIPNYNIDLIIAGETVGRRVERAITGSISKGIAKRATCDVIIVNDS +> +EKYRKILVGVDGSSQSKQALKRAIQVAKDFHAELLIASVQNDAQLVLFLNQCEQLASEQGV-QVDAVMAHGSAKKELAVTIEKYQTDLIVVGATGLNRVEQMIIGSTASYIIEHTQTDVLIVRTE +> +-MIKKIMVAYDGSYEANQAMNIAVNIAKGVSAEIFLVTIFNPFDRKKLNKKAE----DQGI-KVQSKVIEDRIGPNLVNFALL-DIDLIIMGRRSIGAINRLVLGSVSNYVIQAAKCAVMFVKE- +> +KHYKTILVGLDGSANSLSALEKAGELARSMDAKLVLVTVVDPKQAQKMLAHYQVKL-PEKV-KYQAVVVIGDPKEMLSEILKKYQAELVIVGATGLNKLDRFILGSTAAYVVRNTKTDTLVVNE- +> +SNYQHVLIPVDNSEPAEVAFNEAVNIAARHQAKLTILYVVDDRHAAAAMRDRRTFVETTTVPALQTEVAYGDPKRTIIDYAQHPEIDLIVLGATGKDSPHRVAVGSTTSYVVDQAPCNVIVIR-- +> +----------MVQNLLRPPFLKACGAAKRNGAHLVITTIIDTLNAEKMLEDYEKQAKDMGVESVETILDYGPPKATIVEIAEKFHADLIVVGAVGTSRLSRILLGSVAGYVTLHAECDVLVERES +> +QLYKNILVGIDEGPLSQKALHQAIQLAKQNQSTLYVVTVLSEERAEKLLHEAKEAFTNEGV-TGDCYLQFGSAKKLLAETLETWDIDLTVIGAPDKHLENYFGIGSVASYVVRHSKNNVFITKQ- +> +--MVKVVVAVDNSSSAERAFKRAVEVMGG-RGSLVVLHVTEVVTATKFE-GLCHSASPKVAQWEYREVEASSPKEALLRQTELEGADLLVVGRKGMSTLDKLLLGSTSEYVVAHAHMPVMVVH-- +> +AGYERILVAIDGSDQAEIAFQEAINLAK-IGASVALASVIDSREMEAVLSKYVEKA-AAGFESIGTYLEVGNPKKMLSEELDLFGADLIICGATGLNRMEKMLMGSISSYIVQHAKCNVLIARES +> +ENYKHVLLAYDGSVDAEKALFKAVNLARRNNAKLTVAYVVDVREHGKEMKLKMKKIEEYGFDNYHLRIEKGNPKTVITYDLDEVGADIVICGSNGIDSYDQMIMGSTSENIVRYSSVDVLVIK-- +> +ETYKHILMCYDGSKNAEKALMKAVNVAKRNEAKLSVVHIIHKDQHAEEIRRHVEVMDRADFKAFEVLIDTGNPKTKITYDYDDLGTDLVICGHTGMDSYDKMDMGSTSENIARYSSVDVMIVK-- +> +-MFKHILVPLDGSDISKHIFEQAVEIGEHFGIEQMTLLYVYEESAKERLN-ALKEGNSDSF-KINVEVVTGDPRNLISKQYEDDGIDLIVMGATGKGNLERLLLGSVAQYVAKHAEVDTFLVR-- +> +-MYKNIIIAMDGSENAKKALDRAVVLAK-MKAKLYIVNIIDTRVFSKSLMDSYNEA-LADIEDVNIIVEAGSPRTMITHEIRRVNADLIICGASGLSKTARFLLGSVSENIVRTAECDVLVIRHQ +> +MQQATYLVAVDGSKNAERAFQAAVDLATVTGAQLTLLYVINDRAEHELLNTYQKTA-QQQHINVQQAMVYGYPKEQIVTYSDNQPTDLIFLGATGNNAFEDGELGATASYVIRHAAANIFLVK-- +> +KPYSRILIGLDGSDQADRAFNIACVLAQVLSASLYVVWIVNRDQISAKLNPYVKKAADQHI-DVTGKALIGNIKTLLAKDVDEYKIDLIVLGNTGSNMVGKMLQGSHSGYVIQHSGCDVLIVK-- +> +SIKRKILVAVDDSDQARDAFVEAVTIAKAKEANLYLVSVIDEDQRQELLNNYRQAKNQFDFDQVNAEVFVGEPKRQIIHLLEDPAFELIVVGATGKNARERLFMGSVSQFVVRHSPVSVLIVR-- +> +ERYYNILAAVDGSPQAHQALMEAVEAARRNNARLYIAQVVNSSEKEAAIKLLEEEFAGIDYYNKQMVTCVGSPKKVLCFDLETYKIDLIYMGATGKGAVERMLVGSTTAYVVNNAPCNVMVVK-- +> +SNYKNILVGIDGSEESEKAFLKAKEIAKNNEAELVIAWINTELSR--YVSVKEAEAKNDGVKKVISVVMTGEPKKYLSKVIQKFNSDLIILGATSTNIVRNILIGSTAKYVVKNSKCSVLIVK-- +> +-MTAVYLVALDGSQQADKVVRKAVAEAQRSRARLILFRVLETPTRDALA---QQELKQYPELEVSYYLQEGKPTRCIQQFADV-PVDRIIMGITGES--EQNLTGSTTAYIVNHAPCDVLVVK-- +> +-MHEKIMVATMGEY-MDEIMKYTLDIIQERKTEVIGIYVVETSQGEEILESMRQEFQHYMI-NFKKLLREGDPAEEIVKAAEEEGVDLIILGT-GKDIIDKRLLGSVSEKVVHSAPCNIMLIKT- +> +-MYSKVLVPIMGNY-TKELVDSTLDLIGDREVEIIGLYVVDDSKGKIFLEEFEQLLDNKNI-SIIKKLSKGKPAEVIVKAAEDNCVDVIVMGT-GKSIVDKHLLGSVSEEVVHFAPCTIHLVRT- +> +-MNKKILVALDDSDYAKNVMNQALELARSYQAELLGVSVIDTLSYQALIDE---CVKKSNV-NYIHEILEGNPSEEILKHAEKNNVEIIVMGSLGKTAAAGIAIGSVTQTISALSKCSVFIVK-- +> +-RNWRILVPVDGTKEALSAVHLAGELALVMESPLDLLYVSPFDEAQEIFAVAEPLL-PAHV-AHVCHHRTGMPTDEILHFIDEMGIRLVVIGGRKHSRVTGLLLGSVTQAVLEYAHSNVLVAGS- +> +-DHARILVPVDGSEGALRAARIAGEIARVTDGTVCFLYVALFDESQAIFAAAAAVL-PEGV-SHAAYRRAGAAAEEILRFIDETGCDLVALGGRRSSRVSGILLGSVTQAVLERAQTRVLIAGQ- +> +-NIQQIVVPINGTAESFKALSLASDLAKIYQAQICLLLVTYFSYAESVFLRAKDLL-PANI-DISTHHLSGQPASKILEFTKAHNTDLIIMGCRKLNLFSSILNGSTSRQILEKSTCPVIIVK-- +> +---MAILCAVDGTQPHESVVSTADDLARAYDDELIVLHVMTKDMAR---EAAADVL-DSTD-RVVARGRVGDPTAEILEVADRVSARYLVLGGRKRSPVGKALFGSTTQSILLEATTPVVTVMD- +> +---LKVLVPSDGSSNSLYAIRHVIDEFNKGGLEIHLLNVQPPFQADAALIETRRMLDAAGI-PYTVHSEVGNKVDCIVDAARRLHCDLIVMSTARKSSLVRLIENSVTNQVLEKASVPVEVIPGE +> +---IRILLPLDGGEHALDAVRHVIGMRQAGEIEAVLLNVQDPPAGEHALAPAAALLQTADI-AFETVVVTGDAAHEIAEQALLLGCEQIVMTTLSHGALLGRLQDAVSHEVVRRARVPVTLVPPP +> +---MKILLPVDGSALSLHETRFALRLVQEGKAEFVLANVQEPAAGADSMAASAKLLESFNV-PYETAVLTGDPVPAILELIESYGCDMVVMGSRALGLVRTALEGSTSSKLVQDSPVPVLLVKPP +> +---IKILIPVDGSQQSMHAAYHAMRLVSGGKARFVVVNVQEAPAGHDLVRPAVALLSASSQ-LVEQVVASGDPAHTLLELVESHECDAVIMSAHGGGNDVERGLGSVALHMAQHCPVAITIVRPA +> +---MKILLPFDGSPLALEAVKWVIRLCGEGSTSVVLANVQEHAAGAHTLQAAQTLLQEAGL-AYESEVATGDPAHTLVDILENYGCDLVVMGASGASVLRSAFLGSVANELLHAAAVPVMIVKAA +> +---HNVLVAYDGSQPSKRALQYVIEQARDSPMQIHVINQHGAVEADKVLKEAAATLAAAEV-AHKTHAAMGNVAEQVNAAIKQLGCDTVVMGTRGLGSFSGLMLGSVANRVIHEVSVPVILIK-- +> +--MRKMLLPIDSKTVPEKVISYLKDFVPEMNYEVTLLNVISADPSKEMLAGFEEKLRAAGIDAITTMTVTGDPAESIVKIAESGGFHMIMMCTHGMGAAKRLLIGSVTNKVVHHSSVPVFVIRE- +> +---MKILLPFDGSDSSYKALGYVKEFVAGMEYEILLVTVQKTTVHLNLLSDALKYLNGFSHSRIRTYVGFGHAADIILEMSELENLDIIIMCTHGMGAARRFTLGSVTDKVVHHSATPILILR-- +> +--MRKLLVPIDSNTLPDSLKKLLEDFVAVMDYEVTLIYVTPISLAKNMLSEVEAELKAVGIERIQKVHVMGDPAEEILKFAEAGEFHSIAMNSRGMSAVKRLLIGSVTNKIVHHATIPVIVVK-- +> +--MKKILLPKYGSMKMDDLISAAENLAKKFNSTVTVFHVFNCPEFQKELDDTVKLLKDKGIR-VDSKLFKGDPATDIINEAESGNYDIVIMSTQGIPSGQRLLPGSVTGMVMNHIDIPVLVIR-- +> +---MKILVAIDDDSLCQTVIDFVAKVFSHHATIVKLLHVVQPSQASAFLNTLRDLRSKPSE-PVEVSVLMGTPHRVILDCAEEFGADLIVIGSHGHGELSRLKINSVSYAVLSHADCAVTIVKA- +> +---MKVIIAVDESTYGKKIIETIAHRKWQPDTAFRIISVVEPVNATKLCLELKKSLELPDC-TVHYDVLEGSPRKEIIKAAVDWMADKILIGAHGHDLCDRFVWGGVSRAVAVAAPCSVEIVRP- +> +---KSILVAVDGSENSRRAVEHVAAVLVCSCEMVTLLHVIAEPEAETYLEEYKILTGAPSS-RVTVEMDCPSIAQCILAQRESLGADIIVLGRQGRGAREELLLGSVSKRVVHHAKCAIWIVT-- +> +---MKVLIAVEESECSRLALESVVKRHWPEGSQFRVISVVEPM-KRQLVKDDVELLKASED-SVSGDVLSGDVRHCILDESKEWGADLIVLGSHARKGFSKLFLGSVAEGVAGNADCSVEIVKG- +> +---MRILIAYDGSPDSEVAVDEVVARPWPKGSPVRLVTVIETPEGYQRIQKALAKFR-EDL-ETSYELKDGSPKSSLLEAIRDWAADLVVVGSHGSTRLERLFLGSVSHALVTHAPCSVEVVRS- +> +------MVGLDGSNYSNWALFEAISLAKKFNGSIKVISVYKQDEREASKIQHKNLIEKIDC--SFLAILGSNPSLALVETARNENFDLIVVGSRGLSDAASFLMGSVSRKVVSKADCNVLVVKK- +> +------LIGVDGSEHSKKALAEAIKIAEKFGAEVTVVSVFYPATPSAHDFSHRAVLEYEKV--KLISVTSANPSKVITDMARDGKFDLVVIGRRGVGAAHELVLGSVCNRVSCESPVNVLIVM-- +> +MTYQKILVALDRTDASDRVFDHALGMARSSQGQLQLVHSINVSETQQWLEQLRTEALNRNI-AADFVCKMADPGPFICQLAETWNADMIVMGNSGKKGLKKLVLGSVSDYVAKHAPCPTTVVPN- +> +NMFNQILVSIDDSDMTQHVVDEAVSLAKATNGSLMFLHAISLYGKKNWLSSLCESAAYSGV-KAEFTLNVGEASKMICDMARSWNADIIVIGRRGHRGLTELFLGSVSNYVIHHAPCSVLTVQR- +> +-SYRRLLLATDGEATTRRATAAALSLAAAYGADVDALSVVDERSLDASARETAMEGASVGL-SVAPRVETGVPAARILD-VADAGTDLVVVGARRPTDAETRPLGSVSRRVVRGSPVPVLVVRGE +> +-GFKNVLAPVDGSEASRDALQYAVDFAKASGANLHILYVCESLSYEEQMKEALEDFDFGDF-TYEAHFKVGKPAFEIVNAADSLETDLVIMGTVGRSGIAGLFIGNTAERVSRSLSCSILTVRPS +> +-RFRRLLVTTDFSEGTPDALAHAFSVAQENESQVTLLHVIHDVGVRKQLEDLVPTEARNWC-DIVTRVETGVPYRIILRTLEDEKIDLLVMNIHGKGMLDRALLGSTAERVVRAASCPVMLIPPM +> +-ALRHLLIALDGGPCGEAAVTQGLALARALRARVTLLHALEPA-AAALLAH-AGREAAG-V-TA-VALVEEEAGAA--ILTAERRADLTVMGACGLTARGPLGLGSVTERVLRASATPHLVVNRS +> +-KISSIVVPIDLADDNETALNCALDLAGMTGAGVTAVYALRLDELRERTEEIDSSGAAVKG-GIKTDIHGLSPAISVANYASRNNADLIVINTHARTGLKRLVLGSVTERMIQESPCSVLSLRP- +> +-DIKKILVPLDISDTADSSLTYALGLAGKLGASVTVVYVFWIDELRLRVDAVYRDKGAPEA-GIETRLTGVSPALTVTDYADENGFDLIAITTHGRRGLERIILGSETEKIIREARCPVLALKP- +> +-DYSRLLVTTDGSENADTATRHAAAVADRYDALVHVLNVVDIQRLEANGRDAADELRTASV-ETAVTTSLDGVAAGIQEYVSDNDIDFVVMASHGRSNLKRQLLGSVTSQLLRTVDVPVLVTPRS +> +-VPSSMVIAYDFSGPSKRAAEVARAIHGVCHGPLHLVHSYLDVALRLGLEEMAEEFSIDAQ-AIQTHLVTGDPADGILKIAERVGATLICAGTTGKSGIERLLIGSVARRLLHDSPVPLLLAHDS +> +-SIQRLLCPVNYTPVAMKALQSAVVVAQCFEAGLAVMHVLEAE-ALAHLCEWVPEDVRLRC-QVKEMIRRGDAAKQIIEVARELESDLIVLGAQHKRFFDTTVIGTTTVRVTRHAPCPVLVVPSA +> +-AIHRVLVLVDDSDASRHAVDVCMELASILGSHVYALLVLSPLRAERLLEG-RAQKSAG-V-ASTEYTFDRRPDTVVTARACTHRCDLVVLPRHGHAPHHTL-FHDLTELCAMAAETPVLVCPQP +> +-DFHHVLVPVDGSAHSREVLAKVAPFLAEG-AKVSVLRATGLT-YVAHLKEQLGHLEGHGL-NLEPQVIDGEAADSIVHFAEQNGCDLIAMSTHGRTGFRRFILGSTTEKVARQAACPVLAFPTH +> +-DIDGVCLATDGSTGSAAATEHALAIADACDATLHALYAVEPDAFEKHGEKTAERAEEHGL-DTVEAVEHGVPTDIVLEYAERDDVDLVVMGTESKSDVERLVVGSVSQRVVPNASVPVMTARTL +> +-LFRRVLFATDFSEHAARAFDAFSYLRHATE-AATLVHVRSPK-PAERLAERARTLEEWGI-ETRTEVRRGDPAEEILDVEAATSPSTVLVGSKGRSRIRRLLLGSVSGEIVARADGNVFLVPPP +> +-DLSTLLVAFDGSKHASEAAAKACTLALRYGSTYLLSTIYEMSKAAKLQEPIVAMLRERGV-RFERLVEHGDPVFQGLELARKKDAGLAVLGSRGTGSLARVLLGSVAARFISTGVCPTLVVK-- +> +-SFKRILAGTDTSEYGNKAVKKAGMIAKSYKGDLAVLSVIKLPDLEAHLVSLTEDISKEEV-KVEIFVKFGEPYKVVVETAKEWGATAIVIGAYSSENQK--SLGSIGEKIIANSFCPVLIVK-- +> +TQPKQIICAIDFSPLSDEVLIYAAGLQ-RCGAELTLLYVETEIKHLHAFSHYSEILAQSGG-LARFSVGYGDPATEILACAERLNADLLVLGSHGSTAFTRLLMGNTAETVMRRACCPVVIYKSP +> +RTLKKIICAVDFSACSDAMISYAAEMG-CKETELIILHIASENMHLHEFSRYSNILEPHGS-NIRFALQHGDPAAGILGYAAEQQADMIMLGSHGSTALTRLLVGSTAEMVMRQAECPVMVMKTP +> +-LGQRILFCTDFSENANFAFNFAVEAAARPGSQLYLLHVVPESEARHDINEYRSRL-PEDL-ELKVEFRVGKDYQEILNFTHENQIDLIVMGRQGHNALQKAFFGNVTEKVVRKADSAVLMVPL- +> +-LFSKILFCTDFSRESVAAFSYALELCRTKDAEIILFHVIPEPDAKEAIDQYLSRV-PAGT-RVSTRVAVGNAGQQVISLVEKEKIDLIVMGRKRKK-SPGVFFGDSAKATLQKAGCPILVIPE- +> +-SMKHVLVPIDFSKNSEIAMNMALEYFGDKTSSITMLSVYEGSESALIEMTFEEKA-KTKKAVIDSEICKGNPSKVIIDTAKGKRSDLVIMGSQGRGSLKSMFFGGTTYQVSRKAPCSVMVIRQ- +> +-MFKTILIALDGSPVSFRALEMGMEMAKKFDSKIVATSIVNVDQNNQILRTAERQLVNSKM-FYEIVSREGDPKSLIAVIPDNINADLIIMGKTGKGMMTKIFMGSVARYVSENSELPVLLVN-- +> +-MFENILIALDGSKNSYDALNEALILAKKFNTKLYVVSVVNIADAQIILNNSQRIIESHKI-DYEMDLLSGEPRDELIDFANRKQIGLVILGKSGVHALERFFVGSVTRYISEHFNGNVLIVS-- +> +-MFKKIIIAVDGSPVSYRALDYGIELAKRFDSLIELVAVVNTNQVKKHVKVAEQQIKNAEL-SYNVILEKGDPRGLIADVPKHTGADTIVMGKTGRHAIKNFLIGSVTHHVIEKAQIAVLLVD-- +> +-MFQKILVPVDLSETHQNTVRIAAQLAESTKGSGTLLHVVETMRARAHLEKLRATAQ-ANA-NWRVEVLFGKPASEVMRFAADNAIDLIVLTSHRINENLGEGWGTLSYKIGILSQCPVLLVK-- +> +-MFTHLLVPVSRTEAVGRALEVALALAQPAQSRVTLLHVVERLQAARDLETAGERFRGAGV-ALYTKVLLGTRVETLVQYTHEHDVDLVVMQSHPVDADPARGWNTISYKVALLAPCPVLLVK-- +> +-MYDKILIPVDLSSTNEAVFSTVRDLGDPDRTDIILLHVIETLEADAKMKDWAAMIAEDGF-EVQAAITYGERGPEITRAADENEVDLIVQRSHKVSEDAETAVGTVSHQVAIFAPCSVLLVR-- +> +-MYKNILVPTDLTDKNEPAIREALSMAFQSGGQLHLLHVLEKLQADETLTRWQQHFQSEGV-PIEKLIAVGKRAPEIIHYCREVKIDLIVMAARIIKEQQ--SFGTLSHQVALFAPVSVLMVR-- +> +-MFKNILVPSDLTERNHKAMDIAVEMALENRAVVTLLHVIETVRAGRKIDKLIAEYGREGL-LMEKHILYGGRVYQIVNFAVAHGVDLIIMRSHKLDENVTEGWGTISFKVGVLSHCPVMLVK-- +> +-MFRQVLVPLDFTPKNEAAVAVARSVTAVD-GTLTLLHVIERIRSGERMTAMLAGLADAPF-ATRSRIVYGRRAQAIVEVARDLGCDLIVMSSHQIADRPASDWISISHKVAILAPCPILLVK-- +> +-MYHRIVVPVDSAGHSKNALIHAIKLAKQTGSKPIAIYINPIINALDILKDIMVDIGHPPD-AIDRRAATGDPTTLIIKMAAEERADLIIMDNKLFGRLAGF--RGISNSVIKYATCPVLVVK-- +> +INYERILVAIDGSKGAEIALDTAIDVTKRNDAHLDILRVLDLNENEQYLSELRDKLIK--FEQINVHIRFGNPKLVIEDFQPEYNIDMIIVGSTGKSFLHRLITGSVAAHVIRTAKCDVLVARST +> +GTYERILAPIDGSDISEQVANKAASIAHRDSAHLDLLYVIDTNDSQTRLEGYRDQVLE--DLDIDIHMRFGSPKKVITEFPQDHDNDLTVIGKSGLSRLERLIVGSVASFVVQNSKTDVMIVQN- +> +KRSNLILVAVDGSEQSYKAVQEANKIACPE-DRLILLMVKDMR--RSLLEAARLVN-P-----FTTKELTGNTKRKLVDFAREEKADLIVMGATGADFFEHLLLGSATHYVIDHAPCDVLIVRCI +> +APYRRILVALDGSTESDTALNIGIETAQKH-T-LALCHIVDDHKGMDIIAHGRTQA-E--LHDVRIFIQEGSPKEVIEVIAKTFVTDLLIAGASGMGHDQSFILGSVSEHTSRTASCDVLLVRNH +> +TNYQRLLVAIDWTSASEKALELSTMYTREN-LQLDILHVIDSSKNMHKLEGVLARA-LSSEYQTHIHLRFGDPRKVISDFPEEYRNDLIVLGTTQKNRIQRALVGSVSSHVIKTAKCDVLSVR-- +> +MTKDRILVAFDGSAAGVAALEKAVAITDVA-ASIDLLYVIDTRRAEIELEEQAK----ARGIEVRTHLRFGNPRTVVLDAPKDYASSLIILGRSSKRLTSRMFIGSVASFVTENAPCDVLIVANP +> +MAYNNILIAVDGSEMSNLLIKKVHEFV--PEAHIDILIVVDT-DAEKVINKAYD-YAK--HANTDVHVRFGAPKQVIRDFPRDHKNDLIVVGETGLSRLQRAMAGTIPSFVTHTATTDVLIMRTA +> +---------MDGTRATPGVVDKAIQLAIVNHAHLDILNVAQINIVAQRLKDIKTRA-L--VKSASIHVRFGNPKTVIRDFIRDHHNDLIVMGSSSLNRFERALIGSVTAYVIRLAPCDVIVVKQK +> +RSWHRILCAVDLSEASRATVTTAADLAHRTGAELALVHVHEPLRLGAELQRWRGVAQGMGR-PVRALLASGGAAGEILRELGEGGYDLVVIGAHPHRRLGRTVGGAVAARVVREAPCQVLVAHQ- +> +-MSRKILVAVDLDAPFAIAIEHAQRFAAVMGDRLALLHVVERGTLIEAAEGWRERLNETIA-PGQLRLRGGSINEQIGAEIEEQGFELLILGGESRHTLALFFDGGGTARLARHAPCDVLVVAR- +> +-VLNTILVAVDDSPTAKFVIKALGQLRLQPTTNVIFSHIVPTVGADEFYGHLEKQLRAFDC-QTEIEIVAGDPAEEIIRLANIYKADLIIIGNRGLTGVKRILERSVSSQVVSEANCSVLVVKEI +> +-KFKKVLIAVDFSEITRDVVGVGCHFAREYGAQVDFVHVVEEGDLESIEEEIEAIARK-LT-RIETTIVEGHPATTIVEEAHERHADAIFVGSHGWSGIKSFLMGSVASKVLKNARCSVMIIRPE +> +-LRKQILVAIDGSPLSDKAAEEAVRMAATPPYRSKIYAMLVLPVV-ES-DEWQELRRIEEV-PLETKIVYGDPADELMKFADKEKVDVIVIGSSGKGFLKRKLMGSVSSKVAAYARCSVYIVRG- +> +-MLKTILVDVEPDPLAGQVMQTLRQLRLEPSTTVILAHVIVATGLESFHDRIEKQLHSLPC-QSQIEIVTGEPVEEIIRLANIYKADLILIGSRGLTGMQRILLGSVSSQIVTDAPCSVLVVKPK +> +---MKLLLPTDGSTYSRNAAKVAGRIATKHNAEIVIVHVVEDKTWET---GAEQVISSLAS-KLHAEIVDGNAPEKIVKTARLHSVDRIIIGTRGQTGIKKI-MGSVTQKVLQMSDILVLVVPPD +> +-AVEQIVAPVDFSDLTEVALRHVAQIAPLYDVPVTLVHVVEDPYARAAEQRAEEALQSLE---VSYLVHRGQTTSTVVEAT-GHRDTLTVMGTKGLSGLRRVMLGSVTEAVIRASDGPVLAVPA- +> +-GDGTMLVPVDFSEHRPRLLAHAREIAPVYGMDVTILHVVEGRYPGTLAERAEKALAEDA---VSIAVRSGPPADQVLTVAEETGAAFITIATHGRTGLERMLTGSVAEAVIRQAPCSVCTVKS- +> +---MQILLPVDLSQPTEALVHTTAALAHRFNAEVDLLHVMDPERIPP-------------A-TIRFHVVQGQPSREILKFARSHHTDLIVLASPALSRTKYFPASSLTEHIASAAPCPVLVLRM- +> +-PARRILVPVDLQEGTASLLAFARHLAREVGAKVDLLHVLEPLWVPTVRERATEALRAA----PGVYVERGSPASVIGRVADVLDSELILVAPRQQGRVAKALLGSVAGGVVRAAARPVLVARS- +> +--LSDIVAPIDFSKPSYQAYAHARYLAAAFGARLHLVFVAESRSPSEIVDNSRAALQHMG---HKIHIEKGEPAAAVLDLIERKGIGLAVIATRGHSALERLLLGSTTRRLLRMASCPVLTLRT- +> +-TLEHIAFGTDFDKSSLMAKTQFISSLEASQAKGYLLHVFDAS-SQTIQDSVQEQLDREK---VEAALLEGPAWEEITEFSEEKGCDLVILGTHHYQGINRMLLGSVAEKTMRLCHRPVLVVPN- +> +-KVEKIVCPVDYTPACADALLRAAALAPQAD--IVLVRSVDRFG---------PRLRAWV---LK-LMTANASASEIVAFAKDLDADLIALGLAGDRSLV---------KIIQHSTCPVLTVSG- +> +-QPEIVVVCIDPNTPIQKILDAAIDRTGPGAREIVLVSVTGGPDARLVLERAETHCRSRGV-TPRLVVREGGPADEIVTLAAEVGASLVVVGSRGRKGVLKTLLGNVSAEVVERAPCSVLVVR-- +> +-IFRLIVVPVDSSPNSMRAAEVALNMCKEFGSQLVVVSVVDTGDAEHTLEMVEEMAEGYDI-SIKKVKRKGHPHLEIVTLANELKASLIIMGKGGRRGGSRLALGNITERVIEDADCSVMLVW-- +> +-SYKHILALTDFSEYSKKAIEEAANIARCQGSKLTVLHVAHDQEIEDKFNKLEDDVALKDI-DWESNIRRGTPYIESLYEIESGDYDIVVLGSHGDGGFKRIVHGSTAGKILRHCPISVLITKI- +> +---RRVLIGYDHTQVSNAAMEWIVAIFPEDD---CIIVNDD--KSKDALE-VVQWFSTKGF-KQPV--LNGDPAETLKDYAEVNKVDLVIVGSRGLGFFKRQLIGSVSDYLTHHLKCSILVVKED +> +---HLVLAAIDDSSAAPLIVDFLTSHKWTEG----LIHVIAP-YAEKLLLK-KSDMQQKLA-QEITDVVGGMPAEVIVDEAKRLSADMIVVGSHGRTGFTKFFLGSVSGAVVSHAPCNVMIVRVP +> +---KKILAAIDGSVHTQKVLDTTIALAKAFD---EICHAIC-DNGKKIIE-ARKLENNGIK-DSIM--DIANAANMILERIKSENFDLVVLGSRGLNEFEGFLMGSVSDKISHHAKCSVFIVR-- +> +---KRIIACAVDPTSAGYVINWILMNLI-------LMHVRP-ASHR-FLKACATQFWHNGI-DKAS--MMGDPKEELMRKVKDVKADVLIMGARGLGALKRAFLGSVSDHCVHHASCAVVIVKHP +> +---ARLIVGVDESPAARWALAWAIGAARLHR----AVHVSR--RCTEVITSFED-VAGGVE-DRTVVGRVGDPGYHLVDLARE--GDLLVLGRGRRGLLSRIFLPSTSMYCARHARTTVVIVQQP +> +---RKIVVAIDESPCCDNALTWCVKNILR--NDALILMNVQPTLLIEAVGKARK-----LP-DKIAISLKGDPREVLLEEIEILDANCVVMGSRGLGKLKGTVMGSVSTYLLHHVRCCPVICVKP +> +---GCVVVSVDGNEGSMDALRWALDNIKLRPGHFLILYVQPPAITDAILNHALQICAEK---KNVTQVVIGDPKEKICEVIENVHADLLVMGSRAFGPIKRRLVELFH----------------- +> +---RKVVVALDPSEEASYTIDWIVDNFLIPK----HLISAL-EKTNDAMQPFAKKLETANI-KEVLIKSNADSRNIVVDYTEKEKADVLIMGSRDLSVWKRLFLGSFSDFCQHNAHCPVLIVKGP +> +---IDILISLDPSEYSKYTFEWVLQNIIDPQ----HVLTVQ-EKAEAMLKAVLKEAFDGKL-EEML--ASGDARREIVEYSYKASADLVILGSRGHGAVKRVFVGSTSDYCVHNCNCSVLIVKKP +> +---RKIVIALDPSEEASYTVDWIIDNFLMSE----HLISAL-EKTSDAMQPFAKKLEAANI-KKVIISSNNDSRNIVVDYTEKEKADVLIMGSRDLSTWKSLFLGSFSDFCHHNAHCPVLIVKGP +> +---RKIVAAVDDSEVSAYAFTWGLQNLVRPD----AITVAP-ASSKALISKYLKQCANANI-SEGV--VKGEPGSWIVDEANRVRADMVLVGSHAYGLIKRTFLGSVSDYLAHHSPCPLVVVKST +> +---LNT-----VLDLSLYAIQWSKTNFLRVG----VLWVLPDCANTKMKQV-KEDFEQLG---EPLYVESGDARGFIPLYADKLNADTVVMGNRGNSGFRKMLLGSVSDHCVHECKCPVLIVRRK +> +---RSVLLAIDKSKEAAYAVDWALENLIRPD----LLYVAKSASGLDFLDE-ENKLRQNE--AEVRMVRNGDARAEIVAAAEEMNASMLIMGSRGATLLKKALIGSVSDYCTVNAPCPVTVVKPK +> +---MKVVAAVDASEESLHALSWALDNVVRPH----LVVV-H--FA----YPHGTACPVQQS-STHY-VRSRSLTELVCVCIRRQAYSTSRPRRRGLGMIKRALLGSVSDYLAHHASCPVLIVKPP +> +-----VVVAMDGSNLSTQALHWVLENLVFRKSDEIVLFHTQQEAAVEVLESGKTLCEEH---KKVTIVKSGDPRDHICEIVEKEQANVLVMGNNGHGTLKRLLLGSTSDHCVHRVKCHVIIAK-- +> +---KTYLFAADGSEPSKRALTYLLGM-TR------SVHVVT-EYV----LQ----CEAN-I-DEHE-RHSDAPAKELCAVAESGTYHMMVMGSRGLGKIKSKLLGSVSDYCVRHASIPVCIVRAP +> +-----------------KALQWTVDHLYREG-----ITLSL--AAETTLKTYGKLLTSKKI-PTCL--AQGDPRTQLCQFVNDKQCAMLVVGSRGMGAIKRALIGSVSDYCVHHSDIPVIVVKED +> +--MKRIVVAVDGSESSLRAVSHALKLRKLSSVHITALYIGPSCRANEVFKKIDKIAGGKSS-SIEKAIGRGDAAAAISKFAMEGGFDLIIIGFHGYEEESKSYLGGVCYKVLHMCQCPVTVVK-- +> +---MKILVAVDGSPFTKRMLAYLAAHDEWLQQSYVVVTAVPAVEAEKVFKPIRTFFSKQKI-RAEFVAKVGSPADVIATLAKKGDFDLLMLGSHGHNSLGNLVMGSVSTKVLANCTTPVLLIR-- +> +---MKILAAVDGSPFTRRMLAYLAAHDEWMQHEYTMLTVVTAVTAEKIFKPLRTFTGKQGL-QASYVAKVGHAAEVISEAARKGKYDLVVMGSHGHGTLTNLVMGSVATKVLANCSTPVLLIR-- +> +---LKLLLAVDGSRYTRRMLTYIVSNELLFFYDHVLFNVQPGEANNALLEEPTQFLQAHGF-TPLCVTRQGEPAKELVVAAKQFQSNLLVIGCRGQSAIESMVLGSVTAAVLAHSHVPVLVVR-- +> +NMYKHILVCFDDSDGSRKALEIAADLYLLNQCQLSVVQVINGTDDPDLRAEVTEILQSRGI-SFHFDTLYGKTSDNICEYANSNQIDLIVVGQSEEGIFKRIFLGSTEENIIKNTTKDVLVVK-- +> +AMYKHILLAFDHTKSSEKALEAAVGLLALEKAELTITHVSTEKELDEALSSVKHNLDSRGI-QANFYPLSGSPAEAICEYATGNNVDLVIVGRTEKNNFQKWFLGSVSEKIMQESPCNVLVVK-- +> +-MFNHVLVAFDGSDSSRKALSMGMSLCKDKDSLLSIIYVYNKTRLEEIEGYVRGIVNDSII-NSHFVVLEGSTDDAILQYAEKESANLIIVGNSSSSKLRSFFLGSVSEKIIKNANCPVLVAK-- +> +-MFNRILLPTDGTDAMRTVIDHAVDIASRRDAVVHILYVVDDREGETALETTAELFHDSDI-KTTTALRKGDPADEIISYATEADIDLITMGTRRGEYT-ENLVGSVSQSIVARANIPVLTTNLA +> +--MKPILLATDGSEHAQQAAKQAIELAEEQGVPLYALCVVDKRHASMCVSKVADMAEKSNV-RVEGGIRHGIPHEVILEYAAEVDADAIVIGEHGD---HTEHFSGVGGKVAELADRDVIVVKAQ +> +--MKKVVVAVDGSDVSKEVIDYALHYAQREKAELLFLHVVNWYELGDWVQERVVSSGTPKPERMSINVLFGNPYNEIVSFAEKMDASMIMIGHRGLSNLERFFLGSVAAKVVAHSPCSVYVHRE- +> +--MKRVVVPIDGSETSKGVIDYAIYYANREEAEMLFLHVMTIHEFIKFIEERVRASGRGIP-RMSVSVRKGRVYEQIVRFAEEQDADMIMIGHRGLSPVQRFFLGSVAAKVVAQAPCSVYVHRP- +> +--FHTILVATGGSPWSNQAVTYAIEMAKDYTQ-LIILHVVAEPEGRRILAEASALATEAGV-TFSTELAWGRVPEVVCRVAQEHACDLIIVGSRALKGFKRLMIGSISNAIASKSPCPMLIVKW- +> +-MYQRILVPVDGSHQSAVALEKAIQLAQQFQAELFIATVIDQRYAQHLLNQAQIKAKTNGV-LATTILAKGIPKKIIAHLPHQYNIDLVIIGKSQRDVLAKLLSSSTSNYVIRYGKSKVLVVN-- +> +-PPERVLVPTDRSDAADRALSAGIDAAAATGATLHLLTVAETAAAEETLDDARTRAEAAGV-ELVTAVQQGQPYREIRSYIEDEDIDQVVLGTGEESDFGHFLWGGVTAKLVRSSPVPILIARNR +> +-WPERILIPVKFTRHSDVALRCALSLAEAFRAKASLLHVLKNG---------ESLLGERMA-RLGWAIESGDPAATILKVAERDRFDLIVLAAHRKTFWKGFHLGMTAERVLLHSDVPVLSIPTD +> +-PTRDVLVPIDSSQGADRALKEGINLANTTGATLHLLHVVEMALGNETITKGVEAANASVP-SVTSSIVYGRPHREIHSYIKANDIGLVTIGTHGQTDFSQYTLGRVSSNIVRTSPVPVLMVRQP +> +-PYENILIPTDGSATATHAAEHVVDFAASLDATVHVLSVVDDRAATDAVDTVVSEAEARGV-TTVRHVEYGTPVEKIRDCIEANDIQPSGWGRWGGVARIVSCLAVSLKRLCARHQCPS------ +> +-TVKNILYLTDLSKNASQVFRYALQLAKTFEGRITILHVLKNIEIIDGIKAFLRKLREDEGLVASIYVHEGDPVSEILDTADRIDCDILVMGDHSKGRLAYTFLGSTVEKVLRRSRRPVLVVPI- +> +-QIKTIAYATGLGTGAPYVFRYALSLARQYDAKIEIVCGMAPLRVKG-IEAMCRSIIDDGKYVGTINVIEATPDQAVLQCAQRVGADVIVMGTHRRTMDQGALLGSCAVKVLHKSTIPVFLVRI- +> +-MFSNILVAVDGSESAAQAFATALQFASDTGARLHPLFVIDLP------MKHCVGMARVGPEIDDLVRPEEDVAHRIEVAAAKLEADVIVIGTHGRRGPGYAPLGSVAEQILRSTTRPVLAIPA- +> +-PIKTLLYATDLSEGAIYALRYAVRMAEQLDGRLHVVHALRPLTARE-MRSFWDEDPQARDRIASIEIIEGQPAEVILTHASALGADMILMGSHEHG-LVHTFLGTVAMRVMRRAHIPTLIIPY- +> +-RIKTILCPVSLTAASKIVLMAAFREAWAHDAKVHILHVIPSFETRA-LKDLRDHLQRYTEMIATINVIDGDPVIQILNMADALKPDMLVIGTHAKGFTEHTIMGRVATRVLKRIRVPCLVVPP- +> +-DVKKILYASDLEQGSRPAFRRAVSLCGHYRSEITYLHVIEPLSLQR-VERFCESLEGIMPSQVTARVEEGTPWRVILKVADEIEADVIVMGVRHHSAMEKFLLGSTPNKVMYNSKRPVLIVPL- +> +-FLDRIVYATELEPDDARVFRHAVGLARQFDAKLHVITVAKGRALHV-LDAFCTA--PDAGVIAELHVRDGDAAAQILALAGRVGAGMIVLGSHGHSPLGEMLIGSVAHTVLVRSRVPVLLVPI- +> +-AYRRVMLTADMSEGGRNAVKTCAALDIARGARASILHVLDAPEASQ-V--------GEWSFRQDLRQVRSPPAEDILAAAREESGDLLVVGAHGRSGLARFFLGSVAEAVLCRADREVMAIPP- +> +---MKLLVCVDLSPETPILIKYAQQFAQQLSARMCLLHVTDSQEHQQ-MQQLQ-----DAL-SAIGLLVNGSVVTTILKEADKLAADMIIVGSHHKSLLVQLIEGSTSKSLINQANRPVLVVPV- +> +-MFDSILLPIDLNHPES--WEKALPMARRLCGASGMLHILGIVKALQ--DAFIIRL---GDAHATAHVGHGHVPEHILSAAKELNADVIVMASEPPDELRNFLVGSNADKVVRHADRPVMVVR-- +> +-KYKTILLAIDLSENSAYALRHAVAIGRCHNAKVHLLHVLPDVDVRDKVHEFAKSLLNEYALIDDIHVHHGTPS-------------------SGKGRISHAFLGTMAKRLLRKSVRPVLVEK-- +> +-PFQKILFANDMSPQANKALPVALAFAEDGGARLVICRVNKGKAAIDWC-------------DPESIVEHGNPSEALVALADRTGSDLIVLGSRRSTFRLEYLERGVTPAVIAQAKCPVLSLSA- +> +-TGAHVLLTLDGSSNSLLAAQEALSLGRTCTTRLTVISVVKKDRARQMVDEFCARCREENA-VCDPLVLTGKPAKLIKQTALERRVDMILIGGRGKSFMAKMLMGNVTEKVIGKAHCAVLVVTA- +> +-TGAQVLLALDGSANSRLAAEEALSLGRKCRTRLTIMSVSKREAAQALVDEVSAKAREEGV-SCETLVQVGNPVELIVQAAKERNVDMILLGGKGKSSMAKMLMGHVTENVIGRAHCAVLVVTA- +> +-WSRAVLLALDPQAEAAQRTDTAVAVAAECGLPLQVVAVAEV--------AALAVARARDL-PCQGSVRRGKVHEQIVAAADAAQADLIVMGRHSAALGGRAFLGGTAQKVIGLAERPVLVVIA- +> +-WSRRVLVGLDPLQPDVATLALAADVANECALPLHLLCVIPG--------DALARVRDRCP-RADGECRVGRPHEQLIAAAGTHEADLVVIGRHHAHNLDRAWIGGVAQKVIGLAECPVLVHVN- +> +-WQHEILASVGDTPLAQEIAKLAGGIAAACDLPLTIVGIAER--------LYVALASALAK-RVQGRVCDGDPAAQTNAVAREISADLVIIGRQRYHLLP-FMHTSIMQKIIGANEVPTLVVPS- +> +-DYATVLLAVDDSDEARRAA--------EFGMALHVSVVIGEA-RIE---AFAARLD--PR-PDTVVVGPGTPQRALPELASRYLADLVVTGSGSSTRFERVLLGGVAQSVLRHVRSDVLIVR-- +> +-WSHGVMAAIDTSMAAEHVATVAAAIAVQCNLPLTIISVIQH--------HTVAVAAAAGA-RVKSLILLGKPFEQVLETAKSLGTDLIVVGRHGESNVVRTPFGGTTQKIVGLSDRPVLVVRV- +> +-WSQRVLVAAEPGPQGRQVFAIGVAVAAQFSLPLHLVSVVAT--------EMQALAGQGGV-DARGEVRCGKPFTEILAAASESRSDLIVMGSRDDGRIGRALVGGVAQKVMGLTEHPVLVLHC- +> +--PKRVLIATDGSEHSRLAMELIRHVREKIPLKVTAVHVMDTERRDHALSM---ARKILGD-SAECISVKGHPVSVIAEISA--RYDMVVLGSHGRSGIDHLLLGSVAERVARFSKSSTLIVRG- +> +-MYQRILIALDARPVCRAAVKEGVALAAAHDAEAVFFHPLPPFQAGKALSAAQAEAEKAGV-ACIKVMGTESDAHAIADAARKRRCDLIVVATTGKNALLRLLTGSVVPGLITVSTVPVLVVKDG +> +-MFKRLLVPLDGSKLAESALPVVSFLTQVFETSVVLVHVIEQNEAKKYLEEISCLPPDALV-EYHVHTTEQKVAKSIIDHVREFDSDLIVMCTHGGGGAHDLLFGSIAQQVMAFGATPVLVIRPS +> +-MYQNIMVAYDGSDGSRLAFDQAIEFKKALPVKLTIIYVNEQYFSKHMHNSIHQQLEEKGI-QANVLALEGSASKTIPAFIEEQHVDLLIIGNSGKSGLQKFFVGSVSRKLIKEAPCSVLVVK-- +> +-MYTNMAVAYDGSDGSRMALEKAIEFVKIMPAKLSVIYVNEDYYSKHLQESIQRQLDIHDT-RASVLALEGNATKTIVAFIEEQNIDLLIIGNSGKSGLQKFFIGSVSKKLIKDSSSSILVVK-- +> +--MKTILSALDFSPISKAVFSASLDLAKTYGAKLYLLHVIHNLAEEEELSGMQKQAAAQGV-DCEALLLQGDVARVIKDEISRLSVDTCVIGTHGHGIFYKALLGSTSESIIEHCGCPLMLIPA- +> +--MKTIVAAIDFSDTTTIVIDTAVQLAHALHAEIVLFHATPPSILQQHLDNLITQVQKQGL-TVRSHTTSAVQRNAICQALESLHPDFIVIGSHRHGSLYELLGPGICSRIVRRAPCPVVVVHS- +> +--MKKIIAAVDLSDITPKVIETASRLASLSGAKLYLIHAEIPERYFPELESIRKKLEREGL-NVENVLLNGDIGGLILKKASDIDADLIVIGARKHSFLHKLFFEELGINFISKCPCPVVVVPE- +> +--MK-LLFATDLNE-PRYITDAAQQLASRLDAELFVVHVYVPSAEQHDFDTFV--LERFER-PVRPALHSGDPARVILEDATRLDVDMILLGKPRHSAIERMLLGSVTNTVARESKQMVLLIPM- +> +-MFETVLFPVDQRNNALEMANAVITFSENQASRLFLLSVGGFSSHRSLLQETQARVEAVGV-PCEVVDRQVSSAVEICSLATELNVDVIVVGLKSVNPDQDT--DSTALNVIQHAPCPVLVVP-- +> +-MFKSILFPIELTREARTGIEITAEMVKIHNSKLTILSVVEPNQVAKLLEESKSFFASRGI-LAQTIEKSGIPAFTICDVADEINADLIIMSCRGLGLIDEEAVESVTNRVINLATCPVLVVS-- +> +-MFETVLFPIEQRNQALEIVKKVISFAEEHASRLSFLSLVGVQSLVQLLQRTRTAVEHVGV-PCAVVERPACSALEICSLATELNVDVIVMGLQGLNPAQDM--DSTALKVIEHSACPVLVVP-- +> +-----IVVAVDVNDASSTLMAQSIELAVKEGAELAVFHCLRQSHHAEAWLQGLCIAKGKGI---RTHVAVGNPGEDIVEYAGDWGADLIVLGRTNRGTLADLLLGSASNHVVHHAQCSVLLVHT- +> +MAMDKLLVAYDESEGGDRALAIAADLARVNPAHVDIVYVIPIPDGEDMVAQAQEKMGE-DLGRVDSLLTGANPATEIVKLVDQRSYDLLIVGNRGLSGLKE-YMGSVSHKVLHASKIPVLIAK-- +> +MALSKILVAYDGSQAGASALDLAADIAGTNPVKVDVVNVVAIPDAKELLGKAVDHLDEIGLNEVETMLNGTDPAIEISKLADQDSYDMVVIGSRGLGGIKG-YLGSVGHKLLSICSKPVLVAK-- +> +MRTRHILCPTDFSETASHALGYAVEMANLYAVDIRLLNVISLPYADEKMKKMVAEVRPSGL-LVHTNIRSGGVLAQILEEAEEREVGMIVIASHGHTGISHMLSPNVAEAVANQALCPVLVVK-- +> +MRTRQILCPTDFSETASHALSYAIEMANLYQVNIRLVHVMSKPYSEEKLTELVAQIEDDVL-SVTPVIRSGDIFANILEDSVENEVGMIVIASHGHTGLSHMLNPNVAEALANKAKCPVLVVK-- +> +---YRILVAIDLKPGTDRLLAEAQRYAKALDAIVDIIHVADPDLEHQQAQAVADQMRAAGI-RVDALTVQGPTLETIMEEARKFGADLLILGSHQHGALYRLWYGDIAIDAAKEAPCALLVVPI- +> +---KTIVALVDLSSLALEVLRQASSFARAFNCEVVVLHVVPKQSNYAKLLEMIDDLTRAGV-HATVRQMVDAGVDEVLTETSGLQAGLIILGAHPHSTLYHLLIGSMADDVLKNAHCPVLVVPE- +> +---KNILVAIDFNDAVGELLGYAEGLAEKFDAKVWVLHVAEPDEEHRNLQMYCDTFLNDTI-EKEALLIQGSTVEAVLEEAQKLESDLLIVGTHKHSFLHNLLQESVSLKLLKKVNIPLLAIPI- +> +---QTIIAAVDMSPVTAKVVGWAMAQARAFNAQLELLYVTTPEDEQRALAALKAQVAAQGL-KVSEHVFPGVPEDKILQEAHRLQADLIICGRHDHDFFYRLFVGSVGEELLKRSPCPILFVPA- +> +---RNILVAVDFNDALGELMGFAESIASKFGAKIWVVHVAAPDEEHRRLQKLSEAFIDNNI-ESEGLLIQGSTVETVIAEAEKLKADLLIVGTHKHSFFHNLLQESVSLELLKKGNIPLLAIPI- +> +---KNILIPVEFDTNTQKLIDTGSLLAEKFHSKIWLIHIAAPEKERKIIQEYSDALNKKSI-DSTALLVQGQTIETIMEKVDTLHIDLIITGNNKHGFIYKLFIESVSDEIIKKSKIPVLLVPL- +> +---NKVLAPIDFSSVTDEVIAQAIKLCKAFGSELVLMFVTPPHKPGDEIISYAETADAGGV-AVSIVVQQGPTVESILEISNAIDASWIVLGSHGHGALYDLLVGSTVEGVMSVSSIPTVIVPG- +> +---DNIMVAVDFNESIGELMVYAESLAQKFKAKVWVLHVADPEEEHRKLQEICKNFIGEDI-KAEALLIQGSTVETVLNEAKKLKIDLLIVGTHKHSFLHNLLQENVSMELLKKVEIPMLTIPI- +> +---MKLFVAVDFSDPTDLILRVAKRLAKSLDASVWVVHAAEPEEEHRRLQQYADQLREAGV-DAKAILVRGPTVQALLAMAEKQGADHIVVGSHGRGMVAEMLMGSISQGLIRAGRWPVTVVPV- +> +---MKLLVATDLSDSASTMIERAQAIAKTLSAEVWLVHVVEPDGEHRKLQALAEGMRNQGL-KVTALLVQGTTAEKILHEASKLAVDMIVIGTPGRGAVYQLLVENVVKEILQQSPYPVLVIPR- +> +---MKILAGIDFSEVSDQVVNKAAEYALAFDAKLWLVHVAAPNKEHAKLKEYADACEEMGV-RCIPLLIQGTTLDTILEVLNKLNVDLVVIGSHTNSSLYDFVVGSIKNELFHKAKLPVLLVPR- +> +---MHYLVAVDLTEPTQKIIDTLIKCVNKEKDRVWLLHVAEPEEDMCDLEAYEAQIKAQGI-RCQSRIIQGVTVDTVFKKVEKWEVDMLIIGSHGKGLLREVLLGSVSEEIVRRSTLPVLIVPV- +> +---VNILAAIDFSDATNRLVPAITQFSKAHDAKVWLIHVAEEEDEHKRLQELAKELRDQKI-DATALLIRGPAAETILQEAERLDTGAIIIGSHGHGALHDVLMGSTGSSVLRQSHCPVVVVPI- +> +---MKALIAIDLSPASWEVIEQAVKLNQSDDNQIWLLHIANPEQQHQTLQEFAERLRAMGT-ECTALQVQGAYADKILQEAEKLQAEIIVVGSHGKGLVKELIYGSTSNQLVRRAEIPILLVPT- +> +--IQQILVPVDFHQHTDDLAAFASGIANKLGATITFVHVVGHFNAKKKMAALIEQHKA-ASPGCGGTVIIGEVADIIVRYAMDNKIDMIVMATHGAQGIEKIMLGSVADRVLKRAACPILLFNPY +> +--RQHIIVPIDFKTHSDLQANFALHMARLLNAKTTFVHVLRPIHMRKKVDAFIKALDK-RGVICEGVVLSGSIAETVIAHVDEQKADLVVLSTHGAQGIEKVLLGSVADRVIKGVNCPCLVFNPY +> +--IKRILLPVVFSDNDNLAAGYARQIAMCAGSEVDLVHVTPHIVAEKLMDTFIEKALP-GVKVRKKTVLKGQPADEILNYARENSVNMIVLPTHTRKGPEAWFVGSVAERVTKKAHCPVLLVHPD +> +--ITKIVVPVDLEQHTQKLVDFAIYIAKKMGVHLSFIHVTEFYRAKEVMANLIADNKS-QYENISGIVYKGEVVETIVKFAEEEDAGLVIIGTHGAKGLEKILLGSVAERVLKAVHCPTMTMNPY +> +--IKRMLLPVVFSENDMLAADYARQIAMCAGSEVDLVHVTPQIVAEKLMDAFIEKSLS-GVNVRNKAVLKGQPAEEVLRYAKENNINMIVLPTHTRKGPEAWFVGSVAERITKRAHCPVLIVHPD +> +MIPTTVLVPTDGSKPAKAAEVMAAEIAAAMGVEIVVMNVIPMTSAQSVVDAAVKRVGTHHV-TVTGKLEAPSPAQAVVEAHKGGACSLIVMGNRGLGGFGSLALGSVSTQVLHTAHCPVLIVKAD +> +MAASRFIVATDGSEAAQAACRMAAEMAQALRRTVTVVSVVRMGKHEELLEKAADEVTDDSV-QVETKLQSSSPAEAILEARGKQGETHLFIGNRGRGGFAGLILGSVAQAVLHHADCPVTVVR-- +> +VPIKRILIAIDFSDASREAFYAGISLAATLNAETWVLHASEPIGVHRRLDELYAELEAVDR-RKVHLVVRTRAAQEILDTAKAKDVDLIVMGSSQDGGFDS-PMGSTAERVARRAHCSVFCVRA- +> +PFVKHILFATDFSEDASRAQEYAMHLADVCDAKLDVLHVIEAPHS-ESLGV-EGDLARRGTPARVRLLLGN-PSEHIRQAAREQDIDLVVLGAQGRTNVLYGLIGKTAERLIHEGPCPVLAVPG- +> +LEINDLLVARDFSSVSNRAVRYALDVAARTGATLHVLHAEVLHGPGHDIPRFRQ-ESVSAVAIKEVERRDVSAGPAILNYAAETGVDLIALGTHGRRGPSRILLGSVAEEVVRRSDQPVLTVRG- +> +LQIRNVLIPIDFSESSLHAIECALPLIKRLGADLHLVHVFAPDST--IPLIE--KYSIEFRRENIHALKGR-PFEEICRLARDRGIDLIVTSTRGNTGLKHLVLGSTAERIVRYSPCPVLIIRP- +> +SRQPRPSVSRRFSSQRFRPSDGAKFIAHRTGAGVHLIHVHDSG-------RF---HNLPNATARCHILTGH-AFEQICKLAGKIHADLIVMSTHGRTGWRRVLLGSTAERVVQHAPCPVLIARQ- +> +--------------MSAQGIETGKRLGESFGARVHLAHVFPPLDAV----AWKE--LST--GDNLHFREGAPVFDVISSLASEIPADLLVVPTHAFRGVKRFFLGSTAERLVQHSPCPILVDRR- +> +-MYKCMLLPVDGSPPSERAAALGLALAKRLSATAVFVHVVEPHLDQEALEAREQKAGQAQQLTSTQPESRPGVAEALVDAGVAHGCDLVVMGTHGRTGLPRVLLGSVAERMARLAPTPLLLVRG- +> +SLYKNILLGLDGSPTSGRALMEVASFSA-PGSTIRIVHVIEDLDSVESLRAIFKDLRSQGTSLLELRDLGGDVAGAIKAEGDKHDIDLTVLGTHGRGGVRRLMLGSVAEHFVRISERPVLLVHF- +> +KKLRRILVPIDFSEESINTLRIAKLLGERLRAQLDLVHVIAPFPRAILPMV-KREQSVQPLPYSCTTRIGA-PAAEISKAARKIGADFVAIGTRGYTGLKYAFLGSTTTQLVRTAPCPVLVVRE- +> +MDIQKILVPTDFSACAQHALTKAVDLAERFDATLHVLHVVDELAKATQIRRINHDGESIEIDTAVSVHLSFDVAATIHDYIEENGIDLVVMGTHGHRNIERLMLGNVADKLVRHARCPVITVNE- +> +MKLSKIAVGIDFSEESDAAAHQALDLARHVGAELVLLHVGTVRASVQAFDAVEQRLRAQGVEISHA-VRDGFADTGLAEGATELGAELLVVGTHGRSGLKRFFLGSISERVARLSSGHVMVARV- +> +MTIENILIATDFSDASQSALKQALRFANTFGATVHILHVVDELARADALRAIVEDDAGVAVNTHVSMQLSFDVSATINEYASERDIDLIVIGSRGQTDRSAYALGRVASQVIEEAPCPVLAVAE- +> +EKMWKLLVPVDFCHGCTNAFNLALSLAKKQNSKIYLSHIISDPDYASDIHKFGEKKARGISEIDTLITKGY-AASEIVESAKKIEADLIVMATHARKILKHAFIGSIAEKVLRTSPCPVLTTKL- +> +MIYNKLLVPIDFGDCTAPSLHFARVLAA-PGAELALMHVIDEQDTEDYSK--GESLVEDG-FSVNRIVVQGTPKDALLDYAASWKPQVLVLGSHGRTGLRRLLLGSVTEKILRQAGLPVCVVKK- +> +MQINQILVPTDFSENAQHALDYAIGLAKQCSAKLHLLHTPVVPS--EAVTILDASIDDAG-IEHFAAIREGTVHEVIRDYAKEHDVDLVVVGTHGRTGVSKLMYGSVTERVIKTVHTPIIVVPP- +> +KSLSKIILASEFSSTCECAREHAQALALRSGAELHVVHVQVLHPDIKAVEAMAR-VSGLDGAVTQVVMRDISASPAILRYAAEQQADLIVMGTHSRKGMDRLFMGSVASEVIRRSEVPVLAIGP- +> +NRPQTLLVATDFSPSARAAEDAGVAWAKRFGSTLHWIHALEVPAEATIGA-TEARGTEEG-LDGTSHLGDVPAAYAIADRAEELGADLVVIGTHGHRGVRRVILGSVAEKAVKLAPCSVLTVKG- +> +FQPKFILCPTDFSGPATLALYYGKYLSAYFDARLVVLYADQFSV---DLATITREHI-GGSSEVEMVVAENQAVPAILLTAEEKKADMIVMGTHGRSGINRLMLGSITEKILHETDHPVLTVSE- +> +-MYKNILLGVDTQLKNEKAIQEVCKLAGP-DSLVTIVNVISEQKRCEELEPTRRRLTDCDI-QFEELILKGSPKEKLVETANRGNYEIVVLSNRKAEKEKKFVLGSVSHKVAKRATIPVLIVK-- +> +-MFKNILVPFDFGNSFKNVPEQLVKLTGENAYKIVIFNVISETEKKDEMKPFLKSLDDANL-KYDVKFTTGAATKEIVNEVENADYDVVVMSNKRSEIDIKHVLGHVTHKIAKRVNIPVLIIK-- +> +--MERILVPVDFSVYSQKALEAAAYIALQKKCEVKLLHVVQQVYVQRL--GFVDRLKSKGI-KSSGIIVQGKVSKEVLLHAADEEIDLIIVGKKGESDIEEVLFGSTTLKLIRKAAVPLLILKN- +> +--MKKILVPTDFSKLSEDALAFAIEVAQKYEATITLVTSLHYDFYKEQMNQLIARYNVSGV-SIDEYISDETLITILNEKITHEAYDLVIMGTSGSSGIDEFLEGSNTEKVVRKAACPVISISG- +> +--MKTIIVPCDFSAPSRAAYAFAMAMAERTGSQVVAVYVIYIPVLNEQFEEMKRAVAHSSV-HSKLSIVNGSVVFALLAEITHYQASLVIMGTTGTSATQENWIGSTTEKMVRHCRVPVISVHK- +> +--MKNILVPTDFTDCALNAVKFAADIAKKTNATLHLAHIYKRVISKTYIADLSKQDFMKGV-DIRSSLSSVYKLHDILVMEKYHNTDMIVMGSEGVSGIEEFFVGTNTQKFVQMANCPVIVIKD- +> +--MKNILFLTDFSDTANKAVDVAVQLTQKFGATLHVMHSLNTAQQDTNMSELVDQLKAVGV-SPITVMSQDDVMHDAAEYAEDQNIDLVLMGTHGAKGFREAFIGSNAQKMVRECATPVLTLSD- +> +--MKTILFPTDFSNEAAKALPVAAQLARLFNADLHLIHVLQRLMPGAAFDALKATPALNAL-RVHTHVLTAADPADLLDDPRFAAADLLVMASTGASGLKELLLGSTTEHLIRRATMPLLVLKN- +> +--MERILVLTDFSDIARSGLEEAVRLAEQLGQAELLLNTEETSQGKERLQELAMQYSSERV-RIIPFIQVGPVQETVDVFIHNHKVDLIVMGTSGENTFEEYFVGNHTEQVLRIANVPVITIKV- +> +--MNKILVPYDFSDVAKHALNFAAQIARKSAESVTLINIIEQPTPEANMEAIMADESMKDI-KLNYKIVLGNPFKELAAEIETQGVKLVVMGTSGASGAEEFFVGSNAERMVRYSKAPVITVDH- +> +--MTKVLVPFDFTEQAQNALDLTTHLSNKFNVEITVLHVIEVPSAKQQLKDLESQYASNNY-VLKTKIVLGNAFQNISSAIIDQNPDLVIMGSKGSSGMEEVLLGSNAEKIVRTSHCPVLTVKG- +> +--MKKILVPCDFSATAVEAFKFAQTLAAKSRGEIHVLHMIDTAVLDRYFRAMEEAYATPEI-PIRLIKKMGSLVSGVEQYAREQGVDIIVMGTQGHS---QFGVGSNTGKVVRHASVPVLTIRK- +> +--RLNIMVPMDFTPVSFKALEFLAFLMDKTPVDTHLVHVIQVNEATTGFEEIRKQVN---F-EFSSAVVYGGLTSGLTRYAEKNGIDLIIMGTEGADGWFERISGSEAQHVVRFTTVPVITIQR- +> +--MKKIIVPIDFSEEASHALNFAIEFNERVKGEIVLVHVVEMP-VHNKLDEWAKRPKDAGH-KVHVHMKSGNAFTNISKLIAEENAGWIIMGSKGASGIREVFIGSNAERMIRHAECPVIIIKG- +> +--MKKILVPTDFSDCANEASRVAIKIALKTGAELYFLHIHYTIPTKSQLHQVVKEAGSHGV-RANELFVLDTGYEKIENYIAPFGIDFIVMGTHGSHGFKEIFVNTNSQKIIRESTVPVLVVKE- +> +--MKNILVPTDFSENCTKAAHFAIKMAKSYKAEIHFLHQMTTPVDKAKLRELERMAEHEML-KCRTFLQFDSGQKDILEHSGHFHHDFIITGSSGTKGRVREITGSNVEKIVRKANAPIIVIKE- +> +--IKQILCLTDFSESAENAKAVALSIAKRTNARINFVHGMTVGLIKKRLSVLVEECKKDGY-DCSYEIRYADGQRNMSNQLLQGEYDLLIMGAQGFGDRSQFSIGANAVKILRTAKRPVLIIKD- +> +--MKNILVPTDFSDNCEKAAKLAIEMAILFNSEIHFLHQLNTPVNKSKLRALDKEAEHKGL-TSRTFLEFVSNDKAILSHSDNFHHDFIITGSKGLKGFLEQLLGSSAQKIIRSARVPILVVKE- +> +--MKTILVPTDLSPISLQALERAAELTRTYSARILLLHTVIDEDLEAQLKALLSDPLYQGI-EIQIEV--GKTLKGFLDCLSDYNPDLIIMASEGASGLKAWTEGSHAGAVMRQACCPVLILKE- +> +--MYKILCPTDFSTVADIALDAAILLGKTLSAELHLFHCTEFPTYKAELTKRKMKIKAANL-PCLIHVDKGNFINRISELTTLIAFDFIVIGSHGASGKREWLLGSNTQKVVRRLHSNILVIKD- +> +--MKKIIIPVDFSQHSEYALETGAALAKQHNAELIVMHMLELSESNKEFEKFLDKPYLEGL-SVTPLIKHHKVLKEVSEVASYEKADLVIMGSRGHSDHDGVFTGSNTEKVVRYSDTPVLVVKS- +> +--MKNILVPTDFSKNCNKAEELGIEMAKLYNSEIHFFHLMKTSVDKSKLRELEKKAEHEGL-KCRTFLQFDSGQKDILEHSGHFHHDFIVTGSSGTRGGIRELMGSNVEKIVRKADVPVVVVKD- +> +---MKVLIPTNFSPYAEFALGLAKHFGSKMPVEWHAMNVVKAHDDESKKQELANWSSSLPG-EVVNFVASGEVVNQISAYIRKYEIDLVIMGTPGAFGAKNLLEGSTAEKIMRVAGVPVLSVKC- +> +--MDTILIPTDFSEHAHYALEYASFITKEKGGKLIILNVYQHHKE-----SYLKGVDYEFI-TEKGIS----VSNTISKVGIDYHVGLIIMGSNGVSNIEEMLLGSNTENVIRKSHFNVLTIKH- +> +--MKTILVPTDFHVAAENAMAAAVKLAKNMDAKINLMTMFKFPKFAREIERWK--EWYPDV-EIEGIV--KENFDELIPAILSEEADLIVMGSEGANGWKDYFQGTNSQNVVRKADCPVMVMKE- +> +--MKNLLVPFDFSKTSNHALNLALSIAEKQNTTINLLYVVQDPFSKKELKHVIKKFNNNKI-KTPYVTVNASVYKGILKFIDTKKTGLVVMGTHGISNLKTKYLGTNTERVFRMTKKPVIIVRD- +> +-----------------------MEMVARAKAEVVVLHAAYVPVLKRGYEKMKNESGVRGV-SVSLDIVHDNLISAIQHHVDRKQTDLIIMGTSGASGIREVFIGSNTEKIVRFAQAPVLAVHK- +> +--MKRILVPTDFTDSSIFAICTAAGLVEKFAAELILLHVLDEPEDAKKVEKILKLADLQDL-NYHYQQVKG----DLIESIVNQPSDLIVMGSHGAHGLESFFIGTNAEKVAKRAECPVVVLKD- +> +-NMMRTLLAYDGRQQ--RVLDYAIDHALAYKSTLFIISALATKKLKGSLEAAKQRALDKGV-DVHIMTGAGDPATEIVAAAERIGADTIIVGHRDKTVLDRVVLGSISENVLRNARCTVIFVL-- +> +-MLRQVLLAYDGSPSSEDALNLACDLTRGLGATLQVLTVIDQSSALQRLRRLEPMALRAGF-SLQLEVLIGDPAKEILAQVSRLPADILVLGRSRPSTIDRLATSSVVELVLPEAACAVLLPK-- +> +-TDMSILIAYDGRQATEAALEYATKLSVSLEEPLYILNVVSKETVQEYMAAASQKAMAAGA-DVHTIIEVGKPDDVILEVATNFQCGAVVVGRPERSRLDRMVMGSVSQNLVENCKCPVIIVP-- +> +---MSILLAVDKNPNMDNVVKFAIDLAAWRHDEIYAVHIVTGKDGLLLLDRIKDRAAAFGV-FLTPMLESGSVYETILNAAIEKKADLIVVGSSSGKGHQDSRVGSVSEFIVHNAPCTVVVVK-- +> +---MRVLVATDGKPWSDKAVEYAFALYKQFKPTFVALYVVDPKNGMRILGRLKIRGADIGI-EVATLLEAGDPMETIALAADRIKADVVVLSKNPEKSGGGLLGGSTSDFVIKNTNCVVIVVR-- +> +-MYDTIVVPVDGSPEARTAAEQARDLAADLGSSVHLFYVIPATASSRVAELATDVFGDSSV-DVQTTVRRGDQETLTLAFLEEVDADLVVLGRKETPEVRDYLFWSTPAQIVRESEISVLLAHP- +> +-MYNKVVVPLDGSKLAELALPHLEVIGKGCSPQILLISVTERITAADYLCKISEDLEEKGF-NVTATVLMGNPAQQIAWYAAEQSADLIIMASAGKSGISRWNMSHIADKVIKETCIPVLLVSP- +> +MEKEKVLIPLDGSDTSRTILPHVCHFCDAGAEVIILRAKSVPSQLREELQGDIDYLEEKGY-TVSVAIHFGKPVEEIIFIAEQKSVALIAMASHGRTGVKHLLKGSVTEDVLHHINIPLLIINA- +> +-AMKRILIPVDGSETSLKAVKALLDARRYDPERVDLLTVQMPLEGETAVQAASALLTQAGV-PFDVHIEAGAAAETITRVADETGAHEIFMGTRGLGSVSALFMGSVATGVLSLTELPVTLVK-- +> +---TSILVPTDGSAAAGHALERALEIADERDGHVEVYVLTVVDRARKC------LVDDHDA-EIHGAVRRGRPARVVLSYADERDVDLIVLGRTERSDVSETLFGSTVGRVRERATVPVIVVP-- +> +---MRALVPLDGSETALAIMPAVRRLAEMAPGIALHLVTVLDPEWREKLEEVARELPGTDT-HV-HIEWSHHTAKAIIELANELDVDVIAMATHGRSGLSHLLAGSVAEEVIRDSGRPVLVVRG- +> +--LRRILVPVDFWRASLKPLWYASAIARAHGAKIVLLHVTSPVQIRKDLSHLKKNHLPPES-IEDVIIRSGKASEQIIRAAKEFEADLIVLYAHETNESSTVGSHETAERVVRLAQCPVLIVRS- +> +--LKTILIPTDCSDHSRISVKYGIQLAKENDAEIKLLYIQENVLRMSQLQDFWD-SFEEEL-PCEREVRTGDVVSEVIYAAKKGAFDLIIMSSHGYKGLVYSMKGSTTEKVTRYAPCPVLCVKN- +> +-MYRKILCAIDLKKKADKAFEKAVELAHQFNSKIVLLNINDDFSAKKKLDDLKENLETDDI-DISVLLRKGKPGEIIIKTSQDIEADLIVLGANGKDSIADYFLGTTASYVVEHSQVPTLTVPL- +> +-KGRVVLVPTDGSVHSERAYEWYVKNVRMPSDCVKFISVIEPVAGKKLCQQYMHKAKADGI-TSQAFLHDNKPGAALVKSITEHKADLVVMGNRGIGAVRRTFLGSVSDYVLHHAHVPVIIVPPS +> +-AARNVLLPVNLTEHSRRALDWYAANIYKSDDVIHVLYILEPSLSKTLGHEFLLRIQERGL-QGNYVLSGTRPGEQIVSYAKENNVDLIVMGSRGVGALRRTVFGSVSDYVLHRVNIPMAVVPFN +> +-DGRRILCAYDGSKGARAAFEFASERLACPSDSIVLYEAVESIRINQSLQGLQELAMSTKV-PCP-VVMMGDAREAIPEYIAKHPVDLVVVGSRGMSAIKRFFLGSVSTFLVQHCTVPVVVVPPP +> +-QKSRVVIAVDGSEHSDRAFEFYSQNMHKKGDEVLLIHANDIAESKKMLSRFEKKCKENKF-NCKLFTKVGNPGEVICDFTEEKNADQVVLGCRGQGTVRRTFMGSVSEYCIHHATTPITVVPPP +> +-VLRKVLIPVGGSSESKKALAWYNDNIKRDGDLVLFVHIIEPIKARSLFKELIHEANKHDI-NHESMIQDTRTGPALVKLIQEKNIGVVVMAKRDLGFWRRNFSQSITSYVLNHVNIPVSVIPPS +> +-LGQKVLFPIDSTEGCEKGFRWYIKNYYQKGDEIILAYILSPSEARHTFEGYTQLCNEKGI-DHTTILYGTKIGRTIVRAIQENMVDSVVLGFHSMGRVKRAFLGSSSGYVVKRSSVPVVIVPPI +> +--MKSIIIALDESTYSQVIARQGFELATVFKSTVTILLIRNNEKLMIEIQELAKIF--DTI-EYSMTTLEGDPMEEIIRFVTDNTADLLIVGTHGRTGLDHWITGSVAEHVIRHATIPVLVIPY- +> +--MSKIMIAVDLSSYSAGVVAAGIELARSSKAPVVLLTILDKAQVVSSLEVYKDTY--PDV-DITVNAVLGSPNEDILEQVSEQGISTLVMGTHGRTGLDHLLIGSTAEFVIRHSQVPVLVVPY- +> +--IQSIVIALDESDFSPRIASRGFELAVFFNATVELLLVRNNTRQMSNIRQVTQKY--HLV-EHSTTILNGDPQEQIIQFMTHSNADLLIAGTHGRTGIDHLISGSIAEYIIRHSTIPVLVIPY- +> +-LPTKILLATDGSREAGLASRAAADLCLRTSAELHVVHVWTNLGARVLLEQQADKVRSGEVFVAGTHLKEGRIAEEIVGLAENLDVGLVVVGGRSVGAIGRLVTGSISEGVARLSTAPILLVRG- +> +-VYRTILVPLDGSEAAETVLELAMNLAVRSGSVLTLLHVCSQRDMSKICETVQCRFEDVTA-TVFPVLVKGEPAEEIVRYAEENEASVILMATHGRSGLAQSVMSDVTNRVVRNSLVPVWLTRT- +> +-MIRRVLIPLDGSELAEQVIPHLLRFVAPERTELLLMTALSEQEVSERLLEVAQQLNQNGF-RVESKCLAGIPAESILRLAEEAYVNLIAMSTHGRTGLGLTLLGSVADEVVRNARPPVFLVPA- +> +-REPNIMIPLDGSRFGEAALPVALGLAQDLRGQLKLVSVSGPEELSQYLETLGTRIERSTV-PVSRVVLGGSATKALAEFNDLSHPDLIVMSTHGCGPLCRAWIGSVADWLIRHVATPIMLVHP- +> +-MYKRILVPLDGSLTGDRVLPYVRNLGRKLDAKVKLFRVFD-EEVMTSLGMTKTNLESAGV-AAQPDHDCGTPAQHIVAESKKVPDTLIVLSTHGRAGLGRWVMGSVTDKVLHSVKTPMLIIRT- +> +--MPTFIVPLEYHGISERVLPWARALARRLAAPVVLVAVLERAECRAYLEEVAQTFPQE-A-PIRIVIEEGDPALVLTRLAEETADPLVVMAAHARAGWRRVVLGSVTAQVIASGVTPVFVVPA- +> +--MRSLLVPLDGSLLAEAALPYAESIARGARAEVVLFTAID--WAYTYLEQKRRRLETMGI-STRIEICFGPAAQSILTVAERLGVDLIVMGGRHPHGPEPWSCGGVCMRVVEFCSRPVLLVQP- +> +-MAGRLLAPLDGSRLAETVLPYVATIAPALQLEVVLLQAAG--QSKAYLDTVSERLAAFGI-SALVLPASGPPEDAILDSIAQLNVHLVLMATHGRSGLEELLYGSVTHKVIRNSPVPVLAVRE- +> +-MFERILVPLDGSENAEIVFPYCADLVAKFASTVILVTVSE---YRTYLDHALGKMRQDTV-TLGSEVLFGDPAREILRTAEEKDARLILLASHGTSAEGPWFLGHIAAKVLRATRRPVMLIRE- +> +-QIKQVVIPLDGSAEAEITLPYGLALAQHFQAALELVSVDE---FRSYHQHLDERLKSA-P-AWQTYLRSGKAPDEINKFIAEKNADLVILSAHGSSGRGAVLLGKTAAKILSGIIKPAILVQT- +> +-RIEKVLVPLDGSDGAEITLTYALALAGATGAELTLASVDE---YQSYLELLDKRLSELTG-RWQTRLASGKAGDELLRLAGETGADLVVISAHGASGKGAAQLGKTASKILSDITRPVLLIKS- +> +-MIKEVVIPLDGSAEAEITVPYGMALAQKLGAQLDFVSVDE---YRNYLRHLDERLKAQ-R-AWQTRLQNGKAAEEILRFIEEHVADLVILSAHGASGRGSALVGKVANKIMTGTNKPALLIKS- +> +--MQVLHVAVDESRRSLQGIHLGELLHRQWGGTMALVSVVA--KRRAALHDALDRQELGAY-RESLEIVTGDAADVLAGLASDPGEGLLCMTSHGRRPASELLLGSVAAETVRRAGALVVLGGP- +> +-PAGSLVVPLDGSAAAEYALPLAARIAAGYDVPVAFVHVVE--KFRGYCATLAQRYG-L-R-AWTSAVLEGRPADEVLAF--AEGARFVCLASHGRGGFQAMLIGSVADKIVRGAEIPVFFVPA- +> +-RPKTLVVGLDGSPASRGAFAQAMILAASLRGRLVAVAVVPGLPYEEALAEAGEAAAAASL-PLKKVIETGEAFERLVDVAEAEEASLVVIGDARRAYMERVLLGRNVAKVIGYSPCDVLVVPE- +> +-LYEKMLVACGSEPSGLHALKEIIKYIKEDGKPIIVLSVVPFYPFKEALEKAKEIGDQEKV-IVKTVLEEGDPFIKIVDTALSENCDLIVLGRKKELGLMGKLLGANVARTIGQSPIDILVIPE- +> +-RLERLLVPVTGDEHSLYALDQILEFAATRKCRVAVLSVVPPYPSELALARALEMANARGM-DIDCLCEEGEPFEVIVDTARRLKADLVAMGVADRSALGRLVRGNVPLRTIGHSERDVLLVPQ- +> +-NIENILLAIDFSQASKDALKMAVFLAGKNRSRIHLLHVVPRLEAEGMLAEYVEELRQGGVSETQAVALFGNPLEEIVGRANSLDANVIMIGSGEKDKGDRFPLGITAENIIRSSSRPVWVVKR- +> +-KYKKILVAFDGSVSGTNALLQSFRLATEEKSWITVATVVPAYPGEEILSRANALAKKEGA-LIKTVLEEGEAYDRLVDLAEGENCGVIVMGRRGSSSTERSHIGSVTARVIGHSQRDVFVVPE- +> +-KYKKILVPVDGAASSLHALQETFKLTQNG---ISVISVVPPYPCDQAASLALDLAAEAGV-EISVACPVGEPHEVIADIAASEDFDLVVMGLREDQGIIRFFMSGPTAKVIGYSTKDVLVIPE- +> +-MFERLLIAVDGSDCATRAARVGVAVAAKYGGTVDAVAAAHDEDAQRVLADVEAIGEEAGV-TVESRVVTGRPARSVVSLADEVDAGAIVVGRHGHSGFRERLLGSTTERVLRNTDRHVLTVPA- +> +-MLERICIGVDGSDCARRATAVGVAIAEAADAHVDLVYVRKETDANAVLEDALESCEDASV-QVDGHSLTGKPATRLVSFADEHDADLLVLGRIGRTGLGKRLLGSVVHSAFRQSDRPILTVPE- +> +-EEQTFLVAIDFSDCSREVLRWTKSFLAKKPSRIIALHVIDSNA-KAKLRDFLK-ENMREE-HVKMVVCEGTPFLEINKKAVENDVDMIIIGSCGKTGMSQIFFGSTAEKVLRFITRPVFCIPP- +> +-MPKKILVGVDMSKLGENVTLYGLSLAYRLDVDVTFIHVLPHPIAQKRLTYYLKKAEEKDPKKREIVVLEGNPAETIINYAKEKGYNLIIVGSRGHSAFERIVVGSTATNVARYAHCSVLIHRIG +> +-MARKILVGVDLSKMSESLIAYSHSIAHRLNDEVIYIHVLPRLIAHKKISYWIQKAEDQFKHEHKILIEEGSPGEVIIQKAKEENVSLIIVAYKGHSTMEHILIGSTTTTIARHAPCSVLIYRPG +> +-ITMKILVAVDFSPVGREVAHAGYRLAKKIGSEITFFHCAPQTMAKQKLHKIMEDVFAENG-EIEEEVVFGEPGDELLRFAKEKKIDLIIVGYKSYSAIEHLLVGSTASKVARYAPCSVMIYRPD +> +---MKMLIAVDFSPVGREAAFNGYRYAQQLGADVTFLHIVPAMAAAKEINTLVDEIKEKYG-CGVSVNVADNPGSEIIRVADSDGYSIIVIGNKGYTTLERMILGSTALKVVNQAKCSVLLYRHQ +> +-PFDRIVVAVDRSPASGEALARAISLSRALAVPITVLTVVPRLAAESLLANARTLADRNGR-EARVELMRGPPSEAILDYLDESESHLLVVGSRGLSPTRGLFLGSVSTA--------------- +> +-MFKNIMVPLDGSTHSSKAEDIAINLAKRLNAKLTVVYVIDEIEGDKVLDDITKKGNKSGI-TVAIHSITGDPLRDMKVIAEKTKVDSVIISSHGKNSVEDLTIGSVADRVIKTFDIPVILIK-- +> +-MFDIIAVPVDGSDYGYKAADVAIEIAQKFNSKIAAVHVLEEFEGNSILSKITKKANDVGV-EVTEHLLTADPLRDMKFIVDQTRADLVVIHAHGSNNNRDTQIGSVSERLLRTSEVPVLLIR-- +> +-MFKNILVASDGSKCGDKAVDIAIDLASKYDARVAALYIMDFGAGGAVLDDITAKGKEKDV-VVVEHIITADPIQDMETMIRKINPDIAIFGAFGKSTDKYDKIGRVALNALKVAKVPVLLVK-- +> +-TFKKIMIATDGSENAEKAAKVGIDLAKSVGGKVIAVYVMDEREGKNALKRIQKIGRKKNV-VVDEILILGNPIEDLPKIANKVNADIVVLASQSKGKFERIILGSTTKSMLENCNVPLLITP-- +> +-MFKRILLPIDGSENSKKAADKAIELAKELNSTIIVTNIMDQSKSNEFIKKIVDLILKNNI-NVESMVLFGSPMYDIVTIARKSEADSIIMGKQGINYSNSRVIGSFTEATLKNVDLPIILI--- +> +MTFQTIACCTDFSKNADVAVRTAGTLAKKFDAVLEVIHVVPPPDNPNLVLQVEEKLQPGDV-KVRYVVLDGHVSTEILNHLDESGCDLVVVGSYGLSGMGLVIFGSIAKRIAHKANCSVMIARP- +> +-------FPIDDSESCTSAFTWYLNYIKLTGDFITFVHVVEPIRSKALGLSYMNLAKKAGL-ESRFLHVETQPGRAILTSAKNHNIDMIVMESGGQGALSGVSLGRVADYVVHNSTVPVVIVHAD +> +-------IPMDASEHSYRALRWYADKMNNPADSLIFAYIAEPPRGKLMAAEVRQRCTEMGV-KPRLERLTHGAGPALVEIAEEQAVDVIVIGSRGLSALRRAFLGSVVDYVLQHANTTTIVVPPP +> +-------LAYDNSENSQAALSWFARLNAEDRHQLVIFYSVEAPQIDRVRKRCLALCQQLGL-PVKIDKYEAEPGKAIVAMATELDAAAILMGTRGLKRLQRTMLGSVSDYVVHHAHRPVIVVPLT +> +-------IPVDVGEPSKSAVIWYMNNLRKEDDQVLLLHVLEPKVGDKLQKTYKKIFDEQNI-PFDQMCFGKKPIDSVLEIIQSHEITCVVMASRGRNMIERTLLGTVSDGVVHHSSVPVIVIPPS +> +-------VPIDEKEHCVRAFDWYVENYRQERQEIILLHVYNSLQASGMLEGFEQKCKHFQM--PFTRIELGSPGDAICKVAKEENITCIVLGNRGLGAFRRTILGSVSDHVVHHSRVPVLLVPPT +> +-------IAIDSSPNAKKAFQWYVDNLHRPGDHAVLVTVVHIRELNRQLQELAVMMKDAKV-HGTKCVHAARASKGILAAAEDCNASCIIAGSRGLGIFQEASLGSTSEQLVHTSNITVVVCPD- +> +-------FPIDDTEHTLNAFKYFLDKFRLDDDHVILCHVVKGIDHEKLAEKYRLEAKD--I-ETLFELVFGKPGESIVQFAKEEKVEAIVMGSRDLGTFARALNSSVSNYVVHHADLPTVIIPRK +> +NHYQNILLAVDFTDHGQTVAQKAQSLAE-FSAQLHIIHVLDNIYD-DLLEAEKNKFIQLGIAAERRWLIWGEPQQEIIRLAAQERIDLIVAGSHGRHGLAV-LMGSTASGILYHVQCDVLAVHL- +> +SSYQRLLVTTDLSKDCEFILAKAVEVARTTQAELHVLHVAPSDKEMDYTDQVKSLLTRYEIA--RIHVHTGTVKKVVNEYVELMAIDLVVLGVHNRYGLKL-LLGSNSDQLLHSVSCDILAVRI- +> +GEYTHLLVAVDFEPESEVVVARAQRLRHLTGARLTLLHVIEHIYEAELLAVAVRQMDQLDVA--DRLVRVGATGHVIDDVAEELGADLVILGRHGRHGLLG-LFGSTARTVLRHSTCDVLCVKI- +> +MPYKHVLVAIDLTDECESVIHRASMLAKDSGAKLSIVHIVEPMFQQQQFDQAKEKLKSLLRFPLESHLVYGQPRQEIHQLAKNKGCDVIVVGSHGRHGLAL-LLGSTTNDVVHGAPCDVLAVRL- +> +APYQRILVAIDCSDESADILCRAAGVLEGNTGELHLIHVIEPLYQSGLVKQARETALQYQIGEDRIHVELGSIEKTIVDKADALGVDLIVVGSHTRSGLAL-LLGSTARGLVPGAHCDVLAVKV- +> +TSYRRILLVVDLSEDSLLIGRRAQMLAEALGAEIELLHVVEFVPEEELLVRARQRLAELGIPENRCRVEAGNVKSEIVRIARERQVDLIVLGSRERHGLSI-LLNLTEDTVLHAAPCDVLAVRV- +> +HVYQHILCAVDFSSLSEAACQRALALAEQSGARLTFLHVVEYFNAYEA-IEERARLARLACEAAQVLISPHSAWREIVRFAGATGTDLIVLGSHGFHGVAT-LLGSSANALANRAPCDVLTVRH- +> +QHYRHILAPIDFSARSNDVIKRALELAEAHDARLTLLHVVQDVFREQHLASTEKKMHQYKLP--DRAIEEGISTTAILDFATEKQVDLIVIAHSGKKGLLG-FLGSTADSIVKSANCDVLVLRN- +> +HSYRHILCATDFSAASDLACARAAALNECFGAQLTLLHVVENF-QQYREDEARRRLRRVGFK--QQVKFTTESAHAIADYAQAHQIDLVVLAEHEQRGLKA-LLPTAIEHLPQTQVCDVLIVPM- +> +NEYQHILVAVDQSADAERVGRQALIVAQRNHAKITLLNILEGIADSEIIAEAKKSMRKLGIP--DTMVISALSTEGILRAAEELKADLLVIGSHTRSGLGV-LLGSTSGSIINDSPCDILTVKV- +> +SRYNTLLVALDLTQDSAQVLSGAKKLATAGH--LHLVHVAEHPSELQVRQELFPRLQGMALP--HLHILFGDAPQEITYLAGKLGADVIVTGSHGEKGLKR-LLGTTATDILHQAACDVLIVRI- +> +SLYNSILVALECGKDAQQVLNKASALAEQNPSAKIHLVHVVLDWQEALAQSGADYLREAGL---NLIMCFGPPAQQTLKQADNLNADVIVAGSHSRHGFEV-LLGSTAHKILNLAECDVLLVRC- +> +SIYKNILVAIDLHPTCDEIILKAHAFVKEGQGRLSVIHAVEHIAEGEMLSEAKKQLAKFDIS--QQYVEVGSPKIVILDKMKELKTDLIIIGSHGRHGIGI-LFGSTASAVIHHLSCDALVVKI- +> +TVYKHILIAADLSEHSD-IAKRALEIAKCVKAKLSIVHVMAHA-EANLKKEAKKRLTKYHIA--AQYLTEGSIKSAVTQLAKKIKADLIIVGTHGREGLEL-LIGSQANGILHAAQCDVWVIRI- +> +ATYKKILIALDFQSDNSEILAKGREIAGDNAAEIFLVHVNEPLTEVSIRKESEAHMAELNLR--NCIIKEGRPSAEIHAICKERDIDLVVLGTHGQSGLQL-LLGSTANSVLHGSTCDVLSVRV- +> +NNYKYILLATDFSKPARAAAQRAAKLASCFNARLCLLHVVDHF-AVYLSERSIKALEQLEHD--THTILSEHSAHEITQYATQNKVDLIVIGHHGHHGISN-VAGSTSSAVVHRAECDTLSVQS- +> +ASYKHILITSDLSDSSIILCQKASALAGLLNAKLSIIHIVEHLGEEELADEALINLHYHHID--DQYVIVGDKKEEIKAFVIEHHVDLTVVGAHDRHGLDY-ILGTTADNMLHALPCDMLAIKV- +> +AGYRHIIFATDLTEAADTAATRVVDQARCSGGRVTLLHVVEHL-ENYIRERVEKRLARVHLG--RHVALSDYSARAILEYLGEQQADVVVLGALG---NPG-QLGTTVDHVAASAPCDVLIVQG- +> +MANPLWLVATDFSPGSEAAFRRALELAPPLGAHLLLLHVVLDL-QHELEEEAGRKLEEARGH--ARVELRRGTPAAIFAAAHDAKAAMIVVGQAAKAGRAV-CGGSTAAALFHHPPCPVLVVPA- +> +SMYKHILFATDLNTDTV-VARHAVELAQLFQARLSLAHVVTGL-DLIQVQDAHQRMEELGETQLKWLLNSGPVALQIHRLAVEQEVDLIVVASHGQHGFFK-LFGSEATDILEASSCNVLVVKI- +> +KRYAHVLAAVDLAENSEKVVAHAKEMAALFGAKVSLIHVVEPLYESELYEEAKKQLAEFGID--NISVDMGPAKVQILGKAEEGKVDLIVVGTHK-HLFLG-VLGSTANAIIHNAKCDVLTFRV- +> +NLYKNILVAVDLSQDSAVILDKARSIAKAYDAQLNLVHVIEPI-HQEATEQAKQSLMNIDIP--RMHTLLGQPAREIKELANEIKADLIIMGNHGRHGWEL-LFGSTSTGVAHGVNCDLLTVHV- +> +KKYQHVLFATDLDERSESAAEYARDFAALLDAKFSMLHIVQVV-EQQIVEDAHAEMAKLGVE--SCQVVKGYPKEDLLRKAKQMGVDLIILHGHR-HHWLG-MLGSTANSIVNKAECDVLVLSA- +> +PTYNNILVGLDLAEDCTQILRKAADIAGSFHAKLHVVHVVEPLYQGVMENQAAERLEEVGVSVEGHRVCIGQAAGELHRLAEEENMDMIIVGSHSRHGLAL-LFGSITKGVVQNACCDVMALKV- +> +MAYRNILVALDTRDEAAEVLESVQKVMSQEDSSVSIFHVIRPLDESKAIDQAFHWLEGHDIS--SIDVVLGTPTTEIWRKAQQINADLVVLGTHGRHGHGK-ILGSTANGVCNTAPCDVLAIRV- +> +NGYQHFLFATNMSDACNKVIAKR-QFADVFEAKLSVVNFVEP-TETSRQQAAKEELLALNVS--MQHVIVDTPKNGLFDLVESLGVDLVIIGRHNKMDFSW-LLGSTTNAIIHAAHCDVLVLHE- +> +QNYDTILVPIDIYSDYELVVNKAVAIAGDSK--LHLLYVAYPQYSEEVRVQALRLLKKHDIP--QVNVEIGSPADEIHHMADKLSADLIILGTHGQSGLRL-LLGSTANAVLHGVKTDVLAVKI- +> +-MYKTILCAIEASTEGKLVLAKAAAMAKLYNSKLLVMHVLPYK-QKELKEKVTPKIEDFGV---NRIIKVGKPYELICNEAIKRKADLIMLGTHSKKGIQA-LIGSTANGVANYADCDVSLVRI- +> +-SYQNVLFGYDGSPQSMIAFDRAQQIAKRNNTKLIIAMVVKPQQKAKELSRLKQVAESEGVKEVETRLVIGNPRDELTYNLKEEHVGLIIIGSTGLGRVAQVLIGSTASYIVEHANVDVIVIKEQ +> +-NYSNVVVGVDGSKASDRAFKKAMIIAEHNQARLAVIAVINDRQIQSMVSNYVEIAKDRGL-NAVGAIDYGDPREILTSTASDYHADALVVGATGAGIVSRLTMGSTAAYVVTHSPVDVFVVRTD +> +--MIKILVAIKGADSCSKVAQKAQELALLCKGEVTFITIVSNETCSMVYGQCERKLGEKGL-ETKRVVKEGYPAEDICKYADENNFDLLVIADKGDTKLKDKLLGSTTEKIVRESKTSVLVVK-- +> +--MFKILVAVKGSESCSAVAQKAQEMALLCKGSVTFLTIISTKTCSTLYGQCEVELGEKGL-ETERVVKEGYIGQDICNYAEENNFDLIVIADKSDKTVKDKLLGSTAEKIIKHAKTSVLVVK-- +> +--MQKLLLAVDGSKSCSKAVGKVYELADDMDLDVTVLTVLEKAEAKDMVDTCSEGLEKKVS-KLKKEVKTGVPSDVICRTAEEGDYDFVVVADKGRGAVKRFLMGSTAERVTRYSPISVIVVK-- +> +-ASRRILLPVDGSKHSDRAVSWFLANLYRPGDFAVLAFVLEPHEAARLKAKFYQACREAGV-PEHFQLVGSKAGDTLVRYVEESSISCVVIGSRGLGKLRRTFLGSVSEHLLHNAGCAVIVCPG- +> +-FRAIVLIAVDDSEPAEFAFNWYRDFIHKPEYYTVLLHCTDNDRMKRIEEKFGHLMEINGI-VGKIRKGKGKPGEAIVKAANEEGATMIVTGTRGLSKLKRAFLGSVSDYVVHNSPVPVITCRV- +> +-PPRIIIMPVDDSPHCERAFNWYLKRAHRSEDKLILVHVIPPREGRRVLEKYAQKCKKEKF-IYEITKADSNVGNVIIETADEYFANLIVIASRGMSKARRTILGSASHYVVYHAGIPVLVVPP- +> +-MGRTVLLPVDPNENCKHALKFYINNFFNKEDTLIFLHVIDQSNGKALAHKYLAWGRDAGI-NVKAFRSDPKAGEAILTVADELDVDHIIMASRGLNALGRTFMGSVSTYVVHHSSVPVTVVPC- +> +-PQQRVLIAVDGSSHSQNAFDWYRTNLATPGEDVILFHTGSPNRVAQLEESMMEQCKRHSM-QCRWKADSLSPGPAVVDASAEEKADLVVMGTRGLGTIRRTILGSVSEFVISHSRRPVVVVPP- +> +-SANVVIIPVDGSKNSERAVSWYLEHIHSKGDRVVFIHAFDPPKARSLLKGYDEKFATLKQ-LSYKMHDSGKPGEVIINYSKKENGTVLIMGCRGLGKLRRTLLGSVSDYVVRHSSIPVIVIPP- +> +-MFTRILFPTDFSVHAKKVKTKILKMKDCGIKELVLLHVVNKKSAELKLKGWGKDLESTDI-TIKYDVVKGNPFDEIIEYSLKENCTLIIMGSKGLTEAEELLIGSTAEKVARKSKIPVIIIK-- +> +MTTMSILLATDGSPEALSAADWLNRWANPSTVEVTVATVISPPQAQKALDDTRAQLT--RCPPVKEEVLLGAPPKALVEYATTHHIDLIVMGRRGHSALGN-LMGSVSFGVLHRSPIPVTIVS-- +> +VHRGKVMLATDGSPTAINAASWLNDWPHPEEVDVVLATVIAPVTARQSIYETRRKLT--QEFSVKEVILRGPIAQTLVDYAEKHDIAQIVLGCRGHSVLGN-LLGSISFSVIQRSDLPVTVVG-- +> +---MTLLLASDGSEGALKAARWIMEHFGPEHWQVTVASVSRTPEARQACEQTMTVLE--GW-HVDCTVLTPSIADALIGYVRSHPVDAIVVGRRSHSLSRH-LLGSISSELASHSPIPVWVIP-- +> +FLFRKILVPVDGSESSMRALKVALDFAQRYGSRITVIHVKHPSDATPIINAAKKLAGERGV-EVSVKVKASSVASEILSEAIEGGYDLIILGARGNTASEDIIIGSVALSMVVNSATSIMIIR-- +> +YMFRRILVPYDGSANSEKGLRVALELSAILGSKITVAYACEKDCSE-LLKRAREIAEARGI-RIETKLIESSESSEIVKEVNSNSYDLVVVGIRGKTEYEGVLKGSVASSLFVNANVSFLFVK-- +> +FWLRELLVPVDGSGSSMKALDLAVDFAMRYGSRLTVLYACSECSAD-VRKLVEDR-VGGRA-EYRFVVSSSSAANEILKTIAEGSYDAVIMGARGTSINGDINVGSTAIAVAAHAPVTVILVR-- +> +MWFRRILVPVDGSENSMRALELALDFSMRYGSKVTVIYACNRCDAE-VKARVKEK-LNEKI-EYEYRTVDSSISNEILRTLSEGVFDAVIMGARGNTTNSDINTGSNALSIVVNAPITVIVVR-- +> +MWFRRILVPVDGSESSMRALELAVDFSLRYGSRVTVFYACDRCDKE-IRKLVENK-IDNKI-GFEFNTTDSSISNEIIKILSEGVFDAVIMGARGNTTNSDINTGSNALSIVVNAPVTVIVVR-- +> +FSLRHVAAVLDGSRASLRALPVLKDFAQRYGSRITVIYQGSDDFLS----LVKESMSGAGI-TYTV--E---KPSDLLEFIRNKAPDLLVLPLEGRTGAEALESAGPILSALAYTESSILVLR-- +> +--FRNILFPTDFTTHARSALKYAAAFAREGRGRVVLFSVQTAKQLRAQVKDLLIDSLFDGL-EVEPVIVEGEPAHEIAKAVRDYDIDLVTVVTHGRRGLARALFGSTAEEIIAEAPCPVLTIRP- +> +--IRNLLCAVDFTEFSYQAVRYASGIARHFGSHLFIQHIVAVPIAEEELRRLQAEADIQDL-NITYLLNDGSVRSQILETVAQKKIDLLVLGTHAHRGVRRLLGGSLAERLAHEAICPVLVVSR- +> +---RKIVIAVDGSANAKYAFRWYLKHFRMPDDRVLFLHILQAPRVRQIEEDYIAEGQAVAL-NCAFSEPAEKIGEGIIHTAQSLHADLIIMGTRGLRAVSRALLGSVSDFVTRQGVVPVTVVPS- +> +---RKIMIPLDGSSHAEEAYKFYMENICRDGDQLVIAHIVEPPKAAALEEEVHYRAAQKKM-KMDYVEASKRPGDALVDIAWRTNCHMIVMGTRGLGDVRRAFLGSVSDYVIHNSRLAVTVVPS- +> +---RKVLVAVDGSEHSHAALDWYLKKCKRDDDMLYGCIVKQQPRANKEEEYFEMTVVPTKM-KHEFLDPDNKPGERICEHARNKKVDLIIMGTRGLNTLRRTLLGSVSDYVLHHAHVPIAIVPM- +> +---RTVCLPVDGSEHSKRAVEWFIKEVYRPGDHVLFIHSVELPLTNKLNNEYGYICESKNI-PYEFVKNGSTPGAGIIEACEERPVDLIIMGSRGLGRIKRAIIGSVSSYVVHNSNVPCITVPP- +> +---RKVLIAYDSSSSGDYALQWAFDGLIQDGNDVVLVTAVEQSKVSLLSVRYASLFRKRDI-SCQSFILEGDARDVILEVADKTRADCIVMGARGLNAVHRAVLGSASLFITQEAQVPVVVVK-- +> +---MKVFIAVDNSELAEKAFDWYYRELHKDGNDVLVAHSAEYPKYEALKEKYLKKIEDQ-Q-SAKIFEVHEKPAEGLVKMAEKSHCDFIVIGSRGLGAVRRTILGSISDYVMHHAKVPVMVFHK- +> +-KKLKVMVAIDESKNSFYALEWAVEHLKDVMGLLTLVHVNPSGQSTNLFTPALELCRAKMVGKTETMILEGDPKEMICQAVEQNHVDLLVVGSRGLGMIKRAFLGSVSDYCVQHAQCPVLIVRPP +> +-KKTRIMVVIDESDESFHGLQWTLDNLFGCIITLSLVHVQRAGQAKALVSRASDMCKDKMN-EVETLVFEGDPKEKICRAAQEMHVDLLVIGSRNLGKFKRSFLFTFLILFFLPFAT-------- +> +-MIKVIMVGIDESDESFNALRWTLDFLFVSIGKVVLVHVQQPGETTVLLSRALQMCKDKMVSEAETLVLDGDPKDMICQAAEQMQVDLLVVGSRGLGKIKRAFLGSVSDYCAHHAKCPILIVKPP +> +-TPRTIMIAYDHSKASEHALRWALEHQIFHADDIIVAYAIGE-TASAVLD------------HARKLLLSGETKEALVKATKQHHVDMLIIGSRGLGFLKRQLVGSTSDHCVNHCNCSVLVIRPK +> +-TPRRVVVAVDESEESMHALTWCLSNVVSSAPKVVLVHARPADSADTVVAKARNICAAMS-PRVEARVEKGDPREVICGAAEEAGADMVVMGSHGYGFLQRTLLGSVSNHCVQHCKCPVLVVKRP +> +-HGRNILIAIDHGPDSRRAFEWALFNLVRMADTIHLVHVLPA-KQKEAY-------------KTERHIIEGDPGKVLSHESARLEPAAVVMGCRGRSLVKSMLLGSVSEYCTRHCLCPVIIVPHK +> +-SEKKVMVVMDENENSYHALMWVLDNLKESVSTLVIFAAQPLGRSLGLLEKAKSICASRGVN--ETLTEAGDAKETICNAVQKYKINLLVMGGQANRTFMRPFQGSLSNYCLKNAKCPVLVVKKP +> +-DKRRIVIAYDGTEDARKLFDWSIKNIVNPNDHVILVSAQPR-AIRQVLS------------SSEQHILWGDPKETLPKYTQKNKVDLLIVGSRGLGSIKSVILGSVSDRCVHECPCPVLVVRNA +> +-DLETIIVPVDGSGLGEEVIPHVAALASALNLKVTLLRATATAQAIDYMKGLEDKLHKQGV-AVDHRIIRGPADEVIVDLALETPDNMVAMTTHGRSGPARWTLGSVTDRVVRHSGDPVLVVRNG +> +-IETRLVLPLDGTRFAETAIGPACELAASLQAKLHLLNVRGEDAPVTYLGDIRRQVNEKGL-SAVIGIRKGDIAEQIVSYACQNSADAIVMATHAPSELGWFLSGSTAAAVMRQSHLPVLMIPVH +> +-GWPRLLLPLDMTDKAEAALNLSLELARRLRASLYLLKVNN--EANFYLEQIEKLAEEKGV-EVVKIVLVGNPETEIRSFADLFAPDALIMATHAAGTNGTSNPPSLTLEIMRRSHIPVFMVPLP +> +-DGIRLLVPLDQTARSEAALEPAFDLAASLHAPVNLATVFLPPTASGYLHQVTHLAHAKGV-ETQAEVLMGDPYVRITEYAAQIEPDLIVMATHARGEVGRLIFGSVANKLLQNTHLPVLMVPAP +> +-GALCTLVGLDGSRWAESALYPAAQLVSPQQGELHLVRVIQSLLAHEYLKNLVARLKDTSV-RLSWAIVKGSDAHTLLHLTATQLCHLVALATHGRGGFECWVMGSTAERVLAAATRPVLLVRPD +> +-ICRNIVVPLDGSAMAETAVRVVEEMAEKLTGQEMTVNLLHVAQTEAYLRACGAELEKSGV-TVNHTVRTGKPEEVITAFTAESGAAMVVMACHARTGIGRYLIGSTADRILRTIEASVLLLRPG +> +-PPKRVLVPLDGSERAAKVLPYATEYARLFDAELVLMRVCEQPQCSIYLQVVKDRISETGL-KVSAEALLGNAAEEIIGYIRQNRCDLVAMTTRGRSGMAHWVFSNVTEQVLAATSRGILLVRG- +> +-PTKTLLVPLDGSDLAEEVIPHVEILAREESLEVVLLRVAETPSSIEYLERIEKQLKAKSI-AVKTVVVEGKANDEIINYANSNPYTMIVIASHGRSGISRLVYGSVAANLLNGVTCPIFMVKPK +> +-PPQRVLVPLDGSDKAEKVLPYAVEYARLFDAELMLLRICEEPQCSLYLNEVEQRLKDSGI-KVTKESWLGNAAEEIIGYIKQNRCDLVAMTTYGRSAVPRWVFSNVTEQVLATTSRGILLVRP- +> +-LPRTILLPLDGTPLAETAIPVASQFAQNTGATIYLIRVVEPGQAISYLERIRLRLQLAGV-SSCSRIAAGDPADVIARIVHAEDADLIVMSTHGRSGMERMVHGSVVSRIIGNTICPLLLMRGR +> +-TLQRVLVPVDGSSLSLAVMPLASELCRALSATAVLLHVVALGEARQMLEELAEGLGRQGV-RAEVRVAVGHAINQIIQTAEELAPSIIVLSSHGRSGQGRPFMGSVAQAVLQRAPVPCLLAKPA +> +-ALRSLLVPLDGSPPAEAILPWVKELARELKATLTLLRVDLDRAEQMYLAQIQKQLADEGI-RADTVVAVGDPVQEICRHVQEHDVDLLAMVTHGRTGLSLWLTGSVAEAALRSAPATLLLRRPG +> +-ALRSIMVPLDGSAHSESALPYAVELARAFHADLWLVRVVESPVAESYLRIVLERLEGEGV-RGQYRLLTGFAEDELLAFAEDTEIDLVVMATRGRTGMERLTLRDLAGHLLRRGSAPVMMVRKA +> +-RIGKIIVPLDGSTLSESALPFAISLASEIPSDLLITNVISPTDSDQYLFETTNKLSGNPA-TIESEVLEGEPSQAIMALVERHTDPLVILASHGRAGLSRLVMGSVTETLMRTSDFPILVIPEK +> +-PLEHAVVPLDGLAEHEDALQAVIALMPVMVHGVSLLRVIASVEAERYLAAVSDRLVQQGI-QVTRRVVVGDPPTEIRAMI--SAGQLVVMVAHTRVHLIRWFDTLVDDAVEH-GAIDVLFMRSK +> +-ILKKMLVPLDGSLESEAVIPYLSRIALSLNTSFTLFRVITGHSAEAYLRNWCQHLRKEGI-TAEYKVRAGAAAEQIIDYAGKRGFDLVAMSTRGQTGITRWALGSVAQKVLLGGNTPLLLIRA- +> +-TFARALVMLDGSGVAEAALPMIEELTAHPITSVVLFRAITDSAATTYFLGVKERLTGSGL-QIELSVEVGDPTELIRHAS--EGVDVIVLATHGRGGFNRFRHGSVAERIVREADKPVLLVRAA +> +-RIDTLMVCVDGSRPAESVLEPAVNLARRLDARLQLLHVVEVEMESGYVQSLARRIREAGF-EVEWEVLHGDSAEAIHRYLTPCTNAMVVMTTHGRSGFSQVATGSVSREILHKAHCPVGIMRPV +> +-PEHPVMAAVDGSREAERGLELARETAEKLGARVALVRAYSVPAAAAYLKQIARAGE--------TYVVQGAPAAAIEAAANEADAGLVTVATRGLGLARRLILGSTTDRLMRTLRRPLLIVPPA +> +-TLDKAMVMLDGSGVAEEALGITRELAGHPVQEVQFFEAVADPPATTYLMGVAERFAPSGV-KTTISVEMGDPSVLIEAAS--REVDLVILCTHGRGGFNRLRYGSVAESVVQNSTRPVLLVRAA +> +PMNTRLLVAVNGSEESYKALTHAVTIAEEFGSELKIVTVVPTQVYKKVLAKAEAKIRSEDM-NVNAILVEGRPSVKIVDLAEKERCDMIVVGRSPIGMILDWMEKSTSNIVLDDSKVNVMVVAH- +> +-MYDTVLVPVDLAEKGYTVIEHALHVLS-PGGNLILLTALTGYTFDKAVKQVHQKLVPDAN-DCTTKVVEGKPVESILSVAKESNAQVIVMASHKQSRVGYMMLGSIANKVLSHSDIPVMVVKG- +> +-MYKRVLVPVDDTEQSYCAVDVAGWLASASGGSVTLFHVRKPTKQKQIFRRCDKILSAYGV-KANAIAVDANIAGSITSECETGKYDAIVMGHRGRSQLKQLMLGSVANGVLVEAKCPTIMVHV- +> +----GYCEDPTRPSTHRRAVATALDLASRFDAAVHAVSVVDPERASSAADAVAEQ-APAPV-EVSTVVREGRPADAIVNYADEADADAVALGTRGRGGDEGFVLGSVAEAVVRTCERPVLTVRG- +> +---MKILLPLDGSVYSKKAINYLSHLEDIKKNTVFLVNVQKKIESRAILKPAKKKLEEAGY-KVKTKVCFGRATENIVKVSKEIKPDLIIMGSHGRTPVKGLLFGSKTSSVLASTKAPMLVLRK- +> +---MRILVPVDGTEQSRHMLRFLAGRETMLGPDITLANVQYSVEGRQVFDKLRDEISQLRA-DVKETVLYGDAGEAIAAEADRIDADLIMMGTRGLNAPMVYLLGSVSNSVLSKTQRPLLLVRP- +> +---MKILIPVDGSSYSKTALAFLASRRELLAPHIELLVAPEPLSAEDVLKPSREFLAKEKI-HAEEKFLTDEPAQAIVEEAKITAPDLIIMGSKNYGVHSGYFVGSVTGAVLSHTTEPVLVLRN- +> +---MRVLIPIDGGADCREAIRFVTSRKSWENPQIELLYVQKPYKIKAVFEDMAEDIATLPE-NVIKTSKIGHPAKVIASYARETGADLIVMGARGLSALKNLYLGSVSLGTIARATCPVLVCRE- +> +---MRILVPVDESLHSRRVIEFISHRETLLGPEIELVNVQYSVAGKKVFDELGPETLR-RR-GVTERVLYGDIGKTLAEEAEVFKADLIVMGTRGLNPVKGLLLGSVSNDLLARTKVPMLLLRD- +> +---MRVLMPVDGSSHNHAALAFLVGRRSWEAPDVELVHVRAPLAAEEVFAQLEHEAHF--P-TLTKKVLVGSPGLEIAQEAADTKADLIVVGARGHGFIDSMLVGSVSQAVIAKSDKPVLICHD- +> +---MKILIPIDASECSKNAAFWATGKPALFGPEIHIFYAQEPAEAKTVFDSIIDRCGTLPA-SVTLDYGVGSPVQTIVSAGDKLSADMVVMGTHGKGPLDSLLFGSVSNDVVAHSHRPILLIRE- +> +-NLATIQVCCDLVSQTEPLFRWAVNLARPFGASLHCVHALEKPVQQTLLDRLHARLVQTDK-TIATAVVPGTAGDKMVAYAREHKVDLLIVGVKQHRGIQKRLIGSTTDTALRRAPCQVLTVPV- +> +-CFGKIVTGCDVSAKAIPMLGYAMEVAAEFGAELHLLHAIERPVQQAMQDRLRQKLLEAPC-DLKAAVLQGVPGERLSSYAAENASDLIIIGKHQHTAIEKLLVGSTAEAVLRSDPCPVMVLSE- +> +--MQNIVLATDGSAYSDAAARCIADRKLFRDICVHVVHCLPDVESSKVMKSAIDILQGANV-QTLWHALVGFAPERIVAYATAVKAEAIVMGTHGRGAFLDAIVGSVASRVIAHAACPVVLVRA- +> +--MQSIVLAADGSTYSDAAAQCLAAGKLLKGLLVHLVHCMPDVESGRTLRSAAEILSAAGV-PFEQHALTGFAPERIVALARSVNAAAIVMGTHGRGAFLDAIVGSVAGRVIAHAPCPVILVKA- +> +--GRIVVLAVDGSDPAKKSFDWYLDNVHKEGDNVFIVTVGELARVETMLADYVDSLRAKRI-HGEGRQLTKNAGQAICDFAEKNGASLICMGTRGQGLVRRTMLGSVSDYIIHHSKCPCILVH-- +> +--TRKVMIAIDSSHHSEEALNFFFNNCYKPGEDFHVVHVISRPKANALKENYTSKLKALAQ-DEFVRGEVGGVGHTLCREAFDNEISLIVMSRRGVGVLRRTLMGSVSDYVLHHAHVPVMLVP-- +> +--EYLVLLGIDGSDHSVYAFEWYMHNFHKPGYKILLVHVPEISKIASMEAKYMDKMKGRGI-EGEFLRINEKPGPAIVECALEKEATYVVIGTRGQSKVRRTIMGSVSDYIVQHCHVPVLLFR-- +> +--TFKVLIAVDGSIHSEYAVEWYKAHIHDTEYSVVLAHVGEPEKVKNLLKKHSDHLKAGGV-E-IKCVAEGNAGVRLIEIAEKNKVQMIAIGTRGQGTVARTVLGSVSDYVLHHSSVPVCIIH-- +> +---MKVLISVDESKIAANAFDWYFEHIHQDGNEVIICHICEQPKLNSLKKAYETRMEGKNV-TAFLFNFAIPVGEAIIQIANKEQCDAIITGSRGMGAFRRTILGSVSDYVMHHAKATVMVCH-- +> +-SLKSVLVASDFTEASSKPLRHAISIARHYHARFYLAHVVSSVDVTELERKLAERGDLAGL-SHEFIVRQGDVREELEAIIREKQAELVVIGTHGRHGIGKLVLGSVAEKIFREADGLVLTVGP- +> +-KPSTILFATE-SPTHERAFAYALASAREYSAKLILFHAFDTLNEEKHLQPLLDRARGAGV-SAELAVRPGLAAPQILVYAREHAVDRIVMATRAPGRLGKLFIGSVAEEVLRSAPVPVVTIGP- +> +-GLKTIVVATDLEGQADAALEYARKLATNYGARIVLAHGLDPMAARKVLDALAADL-LEGI-HSHSEIRQGTVAEMLVDVARQYEAGLIVIGTKGMEGVGPVVVGAIAEQLVRLAPCPVLAVAA- +> +-RFQTILVATDFGESASAALQYAQALARAHRARIVITHVIDPAERQ-EIQTLEEET-RQGI-PVHSQVQTGMICDRILQSVKEMHADLLILGTRAKGKAGRAALGTVARQVLARTPCPVLTVSK- +> +-NVEHILMATDFSDASRVAGAYAMALGLRFGSAIDAVHIYDPAMRQERLQIIERKM-LLGL-DAHAIHEGHPAAKKLLSLIEERHADLIVLGTSCRTGIDRLLLGSTAEAVLRETCHPVLTVGP- +> +-EVKNILLTTDLTGTHKATLPFANALASRFDSKVHLLHVVTKVTYKTMVA--IMNGIDDNS-KKEILLRGGSFWQVVEKVIQENNIDLVVMGSHGRGGITRLLTGSTAEQVYRHATCPVLTVGP- +> +-SPSQIILATDFSPASSAARSIAGRVARIFNAKILVVHVFQYVDVQQRMSETRKVLTDLGI-ETEGMLEDGFPSVEILNILQSYKNPLLVMGTHAVGGMDRFLLGSTAEEVLRQASCPVITTGP- +> +MDRKSVLVAFKNFKGDRSVLKEATRIARSNNAVVYLLNIVERSRAESEIEKAKDYLKSEGV-EALGLVKFGERSEIICDVAKKIKPVRIVIGNRGLRGIKRLLFGGVPERVVKTSPCPVYVVE-- +> +IKVNPILIIIKDLKNDKKVLKGGLERAIEEGRPAVIAKIIERPKAWQEVDKAIEEGEKLGI-NVYGVIKIGPLEEKINEVAKEVKAKLIVIGQKKISGFKKLVFGHSNKEENFEDTCPVLLIG-- +> +TKSKNVFVVLKDRKQNQTKLETRDYVATNNVEKIYLLKIIDRSRAENDISKFISELGKVNC-QVEGIIKIGSYQDRIEELSKQFNPEAIIVQSSKLSGIKKIFLGNTASDVINNAHCPVIIVG-- +> +-MAKTILAAIRDSVSDRSVLNMAIDLARDEEAKLVICHVINRSKAEKTLSVAADIAKQRGL-DATKIVKLGKPSERIAELAKQLNATNIVLGNRKLKGIRQWLFSEFSTGFNNATLVPVEK---- +> +KTIKKIICPVDVYDFQPEAAEYAATLAKALDARIFVMHVMEPVEAEEKLAEIIAR--FGGDCQVDGEVILGRAADKILQVSEERAGDMVIMASHGRSFWGRAIHGSVTNRVIANAKIPVLVINP- +> +KPIKKIICPVDVYDFQPEAAEYALTLANALEAKILVVYVLEPVNAETKMAEVMSH--FCSICQDKGEVVVGYAADKILEIAKDRDGDIIVMASHCRSLVCRAVHGSVTNQVLANSNIPVLVVYP- +> +-DYNSILVPFDDSVASRLALKKAFRFYNEYGSSIHVCYILPRYEGKKILSSAENMAKEAKI-PIELIMDEGSPAEKIVEIAERKKIDLLIIGPYGWKGLDRKLIGSTTEKILHLINIPVLIAK-- +> +-MFERILVAIDGSANAWRALDHAVSLAKCMETGLGIVHVR---RSQALLHEA-EERVLQGV-RVARHAEEGSVVRQILVRRE--GYELLVMGSRGMGRAAGLILGSVSQSLVANLPCSVLIVDCR +> +-MTRRIVLAVDGDTPQVQLIEWAAENLNIRPKKVHVTILYVTLQKRAELAAVNAAR----L-ELGIKTRPGDARDVVAVKAD--KTDLLVVGSRGLSGAAGMLMGSVSSYLVANAGCSVVVYRGA +> +-MRSRIVVGVSPSLAGLQALRYAVKVARERGGTVDAVRVWLFRLIPH---AFDAAMGPTGV-KIEPVVLEGLTVQSLVEHAG--DDADLLVV-GGDRRGSLLGSGPVTRYSVRHARCPIVVVPPP +> +-HRNTIVVGVDGSEPSVQALRWGFKEALLRDASVTAAIFWTPPVYREVLTEALRRARYEQV-PVLEVVEPGLAGARLVELAE--GGEMLVLGSHGHGHVMTALMGSVSAAVIRKANCPVVVIPTR +> +-QRIHDCVGFDGSEHAQTALDWAVGEAGQRDGQLRLITAWNKA-YPAVLETAAKSAATATG-KVVEN---ESPASAILDAAE--DADPVVVGSRGHGGFPGLHLGSVTTQVINHAPCPVLVVRPK +> +-QQAPVVIGYDGSVFAAHALRKGLAVASALGAPVRIVRAWTISAIREQLAEEVAAELHPDL-AVSLEVPHGAAGRELVNASH--DAQLVVVGTRGLGGFSGLLLGSVSDEVVEHAHCDVLVVRTR +> +-QPAPIVVGVNGSVRSINGLRWAARQARLTGAEVQAVVGWEVPDARQVLDRAVAEVQEPDV-RITAHLIQKRAGLALTNAAE--GAQLLVVGSHSYSELPGVHLGSVASYCVHHASCPVVVIRGH +> +-RKRKIVVGVDGSPQSEAALRWAVGEAAADRGEVRAVLVRARDLLRE---SVRKTLQENPP-LVEDLVADGDPATELIKESS--AADLLVVGSHGARMVTELLLGSVATQCVRHAHCPVVVLTAE +> +-TGQAIVVGVDGSEQSRRALRWAVRQAEATGATVRAVIAWEPPIAEKVLAESVEKAVGSPV-EIRTVAAEGTAAQVLLTAAGAEDVVLLVVGSRGIGGFAGALLGSVGQHCAQHAPCPVVIVRGG +> +--MSGIMVGHDGSNHSQTALREALALAQGLGEEVTVVRAFGLRHVATALKRQIAPALFEDV-PVTVRAVPGKSAAVLIRESE--GFRMLVVASRGLGGLDKLLMGSVSERVVALAPVPVLVTRSR +> +-ARNTVIVGVDGSPQSVSALRYAAQLSAKLDHDLVAFTSWLPRDARDALEATITEAFHVPA-QLGRQVIMGPAAPNLIEASK--SAALLVLGTRGRGGFKGLVMGSVSSSLAAHAKCPVLIHHGE +> +-MGEHITVGVDGSAAGTAALEWALDEGIRSGYRVHVVTVCHPG-ELA---RAVETEIRPEA-SVWRRLLVGSPGPELVRVAS--DSVLLVVGSCGTGGLLATLLGSVSAHCVRHARCPVVVVPAG +> +-MPQTVLVGVDGSDESVRALRWAANQVREVGGIVHAAMVWHQPRARKSLDAVVDGIKFPSV-DVRSRLVRGHVVDEMVALSK--QADLLVVGNKGHGAFTGMMVGSVALKLVHHAACPVVVVR-- +> +-MTRSLAVGFDGSPDAARALRVGLALARDAGATTWVLHARGLLETVTELG--LDP-----A-SVRWRVEDGDPCSVLLGPPV--NAELLVVGRRGHGRHEGLLLGSTSLELVGHARVPVVVVPSP +> +---------MDNSRASAAALEWAMCQVRDG-GTVVAVSVCGMR-------RDAIARIREGV-RVEQSVLDGEPGPALVKLAE--QADSLVLGLHGYRRGGETVVGSVIVHCLKHASCPVVVVSSD +> +-EGDGVLLATDGSSFSENAEKEAINMVSRCDYYICVVSAAANAEAKQRVQRIKTQAENKKI-TIETVTEIGSPCDMIVHKAREKKVDVIIVGSHGRTGLQRLLMGSVCAELIASSPCSVLITK-- +> +-PNKSILTATDFSEYSKITLDMCLGAYRCMKTKLYVLHTIEKFG--QLEEDAIEDVMDK-G-DIIPMVRFGKPFLETIQVAKENSVDLLVIGTHGRAGVDRVMLGSVAEKIVRKADCPVMVIKS- +> +--MSTILFATDFSEASEVAGHVTRAVARHLQARVICAHA--VVFFQEDLAARHEELGRYL--SASSRMLDGSVIESICEAADEAQAALVILGSHGRTGLKRFVLGSVAERVVRLCSTSVLVARA- +> +-KFQRIFAAIDFSSGSDEALRQAHERALSTWAKLAVCHIVPNEIDPFELERVAEVTGRTQA-EFDLIVDEGTPYAAILTHAEKWLADLIVAGSHGAAAAAGLRLGSVANKITQYAHCAVLIARP- +> +-QLKRIIVGHDLGVGGEVALGSAVALANRCGAALRLVHVVEPLE--Q---KTGSPALAR-L-QVEYEVRMGKPFVELIIAGRAWLADLIVVGGASR--TEGPFLGSTSERILRKAMVPVMVTKK- +> +-PVGPVVVATDLSDASRPAIERGGDHAAALGVPLIVCHVVPDVNGPDLIARAADVLGASAG-DARVTVESGAPDEEIVRIAEANRASLIAVGGKPREG-AQIVLGHVAERVVRYAHTSVLVARD- +> +-ISPCLLLPTDFQQPARRAFKYGLAVARLLQTRLKLLHVIKLPY--MMRTSALRLAKDAGV-EAEPIVDFGVPDECILRRLRQERAKLLVMGTEGRTGWDRLRLGSTAQMLVRRADCPVLAVHG- +> +-SNAAVWVASDFSSASDEAVRQADAWATRIGRPLVACHVLPELALDALREHVLTVTRRQPG-EFQTVVEVGQAPSALVRLAEREAMHLLVIGAEAGHG-----LGSTARRVMHYAPVSVLVARP- +> +--MIKIMVATDLSERSAHALQRAVQLIRQGGGEWTLVHVIDDDA--------ERLAEQAGS-KPRMIVASGDVAEVLVESAQGCSAELLVVGAHRKSSLRDFFVGTTLERVVRASHLPVLRVNG- +> +---RRVLIALDGSPGAQKAFNFWANAPGSRNDELILFSSLEMPLGLRVRRRAEVECRQRGL-RCKF-IDSSSPGAAIVEAAKRMGVNVVVVGCRGNNGIRRSILGSVSDYVLQHSARPIVVVPTK +> +---VKVLIAYDGSESSQRAVKYASKVLAQRDAEAIVVTAWESTQARDVHAEAKDLAAAAGF-TAHGELVSTTVWTALIAASDTFDVDVIVSGSRGVSGIRSLWHSSVSEHVLRGCKRPVMIVPSG +> +---VKVLIAYDGTESAQRAVKYASKVLAQRETEAVVVTAWESTQARDVHTEAKELARAAGF-TARGELVATTVWTAIIGASDAENVDVIVTGSRGTTGLKALWHSSVSEHVLRGCKRPVMIVPSG +> +---MSILIAYDGSSDAQHAIEETARLFPG--ASTVVLYARQPLLAHTTLDASEERARALGL-KAEPRVPEETAAEAIVDVAEEIDASLIVLGSRGRRGLPALLSGSTSTRVMHSTGRPTLIIPSG +> +---MTILIAYDGSDDARTAIEYAAAHVRTD-EPAVVLTVWEPLQTWYEQTEAEELARKAGF-GAVTARSNGPNWAAIVDVAESLDASLIVMGSRGLSGAKSVLLGSVSDRVLHHAHRAALIVPPV +> +---PRIIIAYDGSAHADRAVDHAAACLD--PAAAHVVTVWEPLRP-DARERAAARARQRGL-AAEALPSASAVWVALVEAAEATGADLIVCGTRGHGGLRGILTASTAEAVLRESGLPVLVVPPP +> +---PPALLCYDGSPGARRAIDVGGGLLGG--GPAVVLTVWQPVSLA-------TIGRASGI-SGEFD--EIAANAASDCAAQGVELAVIVLGSRGLSGVESALLGSVATGVLHHSHGPLLVVPPP +> +---PRLVVAYDFSDPARRAFELAVFMGRQLDAEVHVVTVLDSRK-----------AGTVQS-DDVKLHLGGEPADAIVAMAREIDAPLIICGTTGKGAVARTLLGSVSHELVHKSGAIVMSVP-- +> +---GTLLIAYDGSADAKTALEYAAKTFPG--REAVVLTVWEPLQGVSVEKGAAQLAIQLGL-KATARWGARSASETIDELADEIGAELIVTGSRGLTGLHSQDPDSASTAA-------------- +> +-TYRRILLCYNATREGRCALRLGAALAHQLGAETHLLAVLDDASAKEILQEGVNKLAELGV-VAVGHLAIGNPMNQIPAFAQALKIDLIVVGHHRSGLLARWWTGQDDGRLLDRVSCSVLVAMD- +> +-MGKVLLAAIDSSPQRRLVLDKAAEIGACMKAELHVVSVNDLSEIHTVLDEARDYLARMKM-DCRTHAPFGATAEQIALLAGELRADGIIIGHRHLSWLGRLVEGSVGSDLVARTPCDVLIVVE- +> +-MYEKIILAFDGSHEARTALREGALLARRYGSRVWLLCVLSDSASATLVEEGLAKLKAFGL-EATGHVVRGDPAPIISAFARKVSADLVVVGHRKRSFLERWWSGSSGAYIVDDVDCSLLVARR- +> +-PFSTILAAIDGGEQTAQVLDQALRLAEGPTATLHLVCVLDTLRARQTLREGLAHLARAGR-SGHAHVVVGAQAPAIIAEAERLGCDILVLGHRHMSLWRQMFGQSTCADVLEQAPCPLLIVTE- +> +-MYKHIILAYDGSITGQKALLELKELAHWGQPRLTLVAVAPNPTLKEQLAQGVQALQDMGY-TV-GEVLKGEVIRELSRFAEHLEADLIVVGHKHENLLRRWWSGSTAKSLVEESPCNVLIVVD- +> +-MYKRILLAYDGSEAGQKALLDCGDLAHLSGAALTLIAVMPLHRHQAVLDAGLARLRAAGH-HV-GEVVTGDSVTEITRRAKEIEADLIVVGHKHLNWAARWWQGAISGALIEHAHCSVLVSII- +> +-QFKRILLPLDGSLLAERILLPTLKIIRGQEIELFMIQVVEKGKAKAYLAEVSEREMPPGV-VVHTHVEVGSAADVIVDFAKAEDIDLILVSSRGNTGFDSWMFGSVAEKVMKGAPCAIMVIRQE +> +-QKIKMLVPLDGSKLAEGALKYVAVLCKQIGEDITLFRTIELFICIQYLQKMQKQLEKEGI-KSKYAVQDGIPADVIIDYSNKNDIDMIIMSTHGRTGLSRWAFGSIAEKVVQSAGSSVFLVRSS +> +-LFRRILVPLDGSERSAAILPYITELTNKLESEVVLLRVVEMGSAQSYLDSVNSKLTGAKV-TVKSEVRVGDAAREIIRLAAETGCSLIAMSSHGYSGIEAGINGKVSKGITEGSSDDY-IGRVT +> +-ILKKALVPLDGSPGSEAVIPYISEIAAKLQMELTLLQIASA-EIDKYLQDWCDHLGEEDI-AARYKVSAGSVADEIIDIADEFAFDLVAMSTRGKTAVNLWSLGSVAQKVFLGGNTPLLLVKQ- +> +-KIKSIICAVDFSEESMKAVEFAASLVGQNEATLYLLNVVKPVESKERIEEIAKTLRNNGLDKVHGIVRTGEPVSSILNTIKEFKGDLIVMGNRKHGFRKGILFGSVSERVSADSPVSVLIDEI- +> +-KIRRIIVAVDSSENSRKCAGFAASLANA-GCETIVLTVIKNS-TRRLHESLVVGSNMFKNKIRSEIVRADDISDAICKYCAETNADIVIVGRRGLGFLKGMLIGSVSEKVTRNCQCSVMIVK-- +> +-MPQTILVPLDQELVIDSVFAAVKRVAGTEKARVILLTVIPEISARNQLERIARGQIDA-H-DWETDVRIGPVGRTIVRRADHFEADLIVMASHNPV-FWDVLLGSIAAQVVKHARHSVLVVRQ- +> +-VFKSILVPVDHRSSWEHALPQALELAAAAKGTVTIMTVIRDMGAQSKLSAIISEQAKDGV-KITSEVRIGSIGREILSVAKDRTIDLILMASHRP-EMRDYLIGPNASFVAQHADCSVLVLRH- +> +-MTLRILIPIDEKRSWTEILPELRLHAKGNSVELTCMTVVPDLVAQSRLGEITETE--EFG-IINRFARSGNIYSEVLQTADELSADLIILMSHIP-DFGDYWLGPNAAKIVRHANCSVLVVRP- +> +-MYRSIIVPVDQPSSWRFALPQALALAEPGGARVALVTVVRELDAERKLAAIAAEAGAGGV-EIAREVRFGSIGHEVLACAAERRADLIVMESHRP-EMLDYLIGPNAAHVAQNAPCSVFVLRS- +> +-MGDKILVPIDDQKTGLKTIAEGVIQATARKGELIVMTVVPDIEALEKLNEIVADHIPSGM-KVSTIARHGTAYEEILNVARDVGATMIVLGAHRP-SLKDYLIGPTAARVVRHAECSVNVLRD- +> +-MAHKILLPIDHEEVLDEVFACAVEQAAMHDSTFVLLSVLPQLEAQRHLDRIGEERLTR-F-AWSAHVLIGHAGRMIVRAADDHEIDLIVMASHNPR-RMDVLLGSVADWVVRHARHSVFIVRQ- +> +-KKPTVLVAIDQPE-QKAVLKRARQLADLEGIRLSVVTVLPDFESRVALHKFIEDTIGDDD-KVKHVIRVGKTYEEILITAEDLNAQMIVVGAHKPN-FRDYLIGPNAAQIARHAPCSVYIVR-- +> +-MFKKILYPVDHVEFAAGFASEVERVAETFGAEIEVMTVMPGFEVERQLGEFASSAF---R-PVKIRVEQGTHWKRILSVAKEDAVDLVIMPHCDKG-WAEVLVGSCAQKVAERAPCSVLLLRP- +> +-IFKNILIPIDDKKSIKGILSKALMLATNFQAKLHFMYVIPEFKYKAQIKELIKQYIPDEI-ETDYYIGSGAVYDEIIKHSNEIKADLIIISAVRL-QLKDYMLGPNASKIVRHSDISVLVVRD- +> +-MYKCILVPVDHEHSWQSLLSASIDLARRHHAQLMVAFIDPNSRPNPFI----AEHIKN-I-RVPFQAEQGQIYSEILYIASVLNIGLIFMALHTPN-LANQLIGANAKKVVRHPQYSGMVCKK- +> +-MHERILVPIKHAALSDESMMKALSIARARNAEIIALTVVPEIDSKPELEAFVKRHDDG-I-TISSVIRTGQPHRAIPRAAREFGCDLIVMNSHNPR-IRDYVIGSTAAHVVMHAECDVLVVRQ- +> +-MIKSVLCAVEDKETDRLVLEQAAKLADLDGAQLDVVNVLPDFDTTARLKSVCAEILGEDA-KVRHVVATGTAYQEILKVAEAAGSDLIVIGAHKPD-LKDYLLGPNAARVTRHSECSVFVVRG- +> +-MLNHLLLPIDHPSSWETALPTAISLARQNHARLTLLSVTPNFALHDRLQVFVENHLPADL-QSDFLVADGKVWEAILGSADKLGVDLIIMASHKRPKLERMLLGTNAMRVVQQAPQSVMIVRT- +> +-MFSKILVPVDIAEETRKLLSRAKTLSDQWQSEVHVVSVIPNV---ETEAELARQIDAAGL-TATGHVLIGTVYDKVIALAKVLDVDLILIAAHQP-DLKDYLLGSNAARLVRHSERSVLVLRD- +> +-MFDNILLTVDDPKSWEKALPQAVDMIRLSKGTLHILSVVPDMRAAKALEKLVEREVPDDV-KVKQHLKFGKIHREALKTIKKSNADLVVMGSEHPDSLREFLVGSNADRIVRRSPVSVLVVRA- +> +-DTSLILCPVNHVQLNVTAYEEAKAMARRREAKLLVATIAPEMQLKSFVEQHPAEGI-----ELETVVRLGAVHRQIVKLADERNVDLIVMESANPR-VQDYLLGTTASHVVAHAKCSVYVVRG- +> +-MFKSVLLTIDHPASWEKALPQAVEIVRASKGTLHVLSVVPDLAANTALNDLVTREVPQEI-NVKQHLAFGKIHDEVLAGIEETGCDLVVMASHQPDRVREFLVGSNADRVVRRSPVSVLVVRA- +> +-MSKRFLCAIDHED-AKALLTEAGRLARLEGAALSVVTVLPDYSAQEALHQMERELLSDLA-PVQSIVVVGSAYEKVLEAAETVSADLVIVGAHKPD-FATRVIGPNAARITRYAQTSVLVVRL- +> +-MFKNVLLAIDHKDEQNEAIEAAKKYAG-EGSHIFVVSVIPPLKAKEALHYFTKERMPEIK-DIKHLVVHGKVYEKITDIAEQLDIDLIITMASIKRDHQSSGFGPNVARIVRNSDCSVLILR-- +> +-MFKDILLAIDDSSTWDRAAPKAVSLAKAFGADLHVMAVVPDFEANARLHAWVSENIPPGI-KVQHIVGHGRAYEEIMRIAGDIPCDLLILSARRTDEGDSYEVGPNTAHIVRHTNHSVLIVR-- +> +-MYKNILIAIDNLDSAKYVVDTCLKLTD-NQAIFRVVTIIEP-EANKALHEFTEKAFK-GA-KVQHIVSYGTIYEEINHLADEKNVDLIVMLASSPN-A--KGLSANTVKVARNTDKPVLILR-- +> +-MPENVLLPIDQTESWEMALTAARRQVD-EGGRIHLLGIVPDIAMKDGLDRFAKEHFPDGA-KVETHVGHGHVAETILKIAKKARADIIVMASPQRDELRSILISSHTNAVVRHSPCSVLVVR-- +> +-MYNKILIVVDNIKRAEEIVRIAQDMTH-NNAVYRVATVIEP-EANKMLHEFTKANFK-GA-KVQHIVAHGSPHEEINRIAHDKSIDLILMFAKKDS-K--KGLDPSTVKIARDCEKPILLLR-- +> +-MFGKVLLAIDEAQGSARAAKAALALTAQSGGEMHVVNVLPDSEAKTALRAFAGEHLPGMP-ERAMHIVQGTIYDRIIATANDIGADTIVVGSHRPE-FKDYLVGPNAARVVRHANQSVLVVR-- +> +-MYNELLLAIDNPQGSQLVVETALHLTQ-NNARFRAVTVIEP-EVNKALHQFTQTHFP-SA-KVQHIVAHGTIYEEINRIAAEKQVDLVIMLASSPK-A--KGLSNNTRRVAKYGTTPVLIVK-- +> +-MFKKVLLAIDDKEAHDKAFTVARQYAA--SELY-VVSVIPPVQAHAALCAFSDSKLG-LQ-NVHHMVAHGKVYEKITDIANELHIDLIITMASMQK-H--RAFGPNVARIVRNSDCSVIILR-- +> +--MAIILIPVDSSTHSEYCLDFYIKQLHREGNHVFSVYVGDYYKSAQIEEHVLQVLKENNI-TGTFKRVLKDVWHTIVEYSKTIKADMIVLGSRGMGKIRRTILGSVSESVLHHSHIPVLICKH- +> +-------MPLDASSISSYCIHYYIEYIHKPENTVHVCFVANDFQCQMINAKVKDLFTTNGV-KFEFHRLTEDPWSIILNFRDEIEASLIVIGSRGQGALRRSIFGSVSDKVLKNSKVPVLVVKE- +> +--PRKILLAMDGSSHSEFAFEWYTTNLMKSDDQLVIVSALERHEHRILVNNLTKKLESTGL-KGMVKTQLGKAGEVVVKVASEEHVDHIICGSRGHSQIRRTLMGSHSDYILHHAHVPVTVCRH- +> +--SRVIAIAIDERDVAESAFQWYLDNLQRKDDFVVLIHILEYPKLDTVEERCKEHLQKLQI-K-KF-RTGGKSGPLIVDIAKQERATMIVMGSKGRGHTRRTLMGSVSDFVVHHSPIPVLVYRP- +> +--GLVVVLGVDQSEHSEYTLKWYLKHVHRSDHKLHLVHVPEHVQMTDIMNNYLQWCSQNGV-PDKFAHPNHEQWHEIIKYAEDVQAGLIVLGNKGQGKLRRTLLGSVSDSVVHHSPVPVLVCRN- +> +--QIKALIALDYDPSAKIIAEAAFGFAKSMGADVVLLHVISDPKSQHFLNHFKGHYGDKK---TETILCEGDFSTQILATAKDVHAGIIIMGSHSHNWFENVVLGSVTSQVVHESRIPVLVIPV- +> +--TTKILIALDYAPSAQQIAEQGYELSKQLHAEVIILHVIEDLEATVYLEKTKLHLQDKA---IKTKVVHGESVQAILEIASQLAVNYLVVGAHSKKSQDDMRVGHTTSHLLKHATMPIICIPT- +> +--MKRVLVAIDFLETTDKVINYAKKMIKESRGQLLIVHSETLEQLEDRLKEIHNNLSKDGI-KAEYVLMEGSTVDNILKEADIFKADLIVIGSHKHGKFHNLLFGSIHKSLIALSQIPVLIVPS- +> +--YKTILLALENNEKDFPIIAHVKELAFFLKAKVYLLHVMAGFN-KEKLMAVAKLFQEKGI-DTEIIIQYGDAASHIAEVSIEKKVDLIVMGSHCHGLVGSIFWGSTAIPVRKKAKAPILLIRS- +> +--MKKILIALDYNPNSEKVVEKGYELAKLMGAEICLFHVLSDVVAIDYLDKAKKHFGDSNEVIITTHLAEGDTAKEVLKYAESWGAHLIVMGTHSHSTLEKIFLGTVASSVLERTKVPVYMVPV- +> +--MKKICIXIDTSPSAEKVAKLGYEYAQALNAEVVLLHVIYDVETEIFLKATAEYLGNPS---IETKVLEGIADSEILDFVNTWGADLLVIGTHSHSFMENVLMGNIATKIVRHSKTPLLVVPI- +> +---MKILIAVDESLFTKKSFEFITTNSFKDIEELHLVHVIPDYQATELLEKNLGYINDMEVIKIPEILQGESIAQCLCQYCDTHEIDLVLIGCRGLSDYDSLSLGSVSHNLVNQSKISVLIVK-- +> +---NKILLAVDGSAYDEKSIAFINNKAAVRDIEVYVASVLPDIHTEKLLAHTVQK---LTVGKVFWNILEGDVAEQLLEFAEQTGIDLIVMGCRGLSNYEELVLGSVSMKVIRLSSRPVVIVK-- +> +-MGHRILVPLDGTRLARSVLPWADLFAQALYAETELMRVVEPLDA---LASLRA-SEIHGR-AASIHVMRGEVSETIADRANALQVSLIIMASHSRAEPARTIIGSNVASVIHRSKVPVLVIRP- +> +--MGRIVVGVDGSDASKRALEWAAEEARLHGASLELVFVYHPPETDAIRQDAERVFATEVV-PVTLAVEDASPANALVDHSR--GADMLVVSARGMGAFRRLILGSVSSQLAHHAECPLVIIRGG +> +--MKKILVGIDGSQESINALKYAAKMAKLTGAEILGVNVINEPEYD--LAEAEDIVEMEGV-AIKTQVDVGSPDDVLAENGN--NVVMIVVGASGRGRGSRVFVGSKTHAIAAGLQCPIVVVPGN +> +---MRIAVAIDAARASARAMRTAVDEARAHGGGIDVIYVYREAAAGRDDRQARAALELDVV-EVRVVLTGANPARTLIERSS--QYDLMCVGSRRTGVFRDLRPSVVSELVARRAHCSVLISRGP +> +--IGTIVVGTDGSAGAERALHWAIEEASLRGTALQVVVAVDPSVTDDG-RAQARR----DA-EVSVGVHEGAPVDVLLSVAA--GAQLLVVGSHGTSSIRHNALGSVSDVLARVSPCPVVILPMG +> +-MFKRILVPLDGSALAEQAIYHAEQFARIFGSKIILLQVLDPAKAEIYLEEVTKRMNDLLEDRVEYAISEGKTAESIVNFAHQENIDLLIISTHGAGGLSRWNISSITQKVIDMIYLPILLIRS- +> +-DAAAIIACLDLSPHSQRVARLAAFLARETDRPLILFHAVSDERARRFLEEMAASI-NFPG-EIGIGIKEGQWQAGLAELCAMSGPATAVIGKSSVGDH-----VHLSASLLESGAGSLLVVPA- +> +-VFRHVLACLDMSPFSHAVLAHASAVASMMNARLTVLHVLEPSDVEAALRDRMSRF--DGI-DAEIVLIDGPAAECICAWVRDHGVDLTVLGVSGNSNWPFPGLGGTARRVAEAIEGSVLLAPS- +> +-VDGGVVACLDTSWLSHKVIPHAAAIAHALHASLTLLHVLEVASAHDYIRRLASER-DETF-HIDTIVVEGQPAEQICLWARNQKVGLIAVGTHGDSGAADWALGETARKLVETCSGALLLVPS- +> +-MFARILVPLDGSALAEGSIPHAEMFARIFGSSLILLQVLDPTEADAYMQGIANRVRNLGENRVIYYVREGKAAENIIDFAHTENVDLLVICTHGLSGLSRWNISSVTHKVINLIYLPVLIVRA- +> +-MFQRIVVPLDGSCLAEWVLPHAINLTKTLDIELVLIRVLQHEEAAAYLDAIASRLGALGL-HPETVTLEGEPADQIINFCRGDGHTLLAMTSHGIGGISHYMLGSVAHKSILQAHVSFLLVRA- +> +-MFDPILVPLDGSQLAECVLPHAVAIARSFNAQVTLLRILEKNKASLYLEKTKMHFQEAGL-RAQVTVQEGLVAEGITEFAQGQRMKLIVLSSHGRNGATPWGMSSTSQKIILSAPTSIFIVRA- +> +-MFSNILVYLDESY-DDGQLPYIASLAQHTRACMTILGHTQ--EAEIELDSMVQVLRDENIDILLDASEYASPAHALAHHARLINADLLIIGSSSRGLLLDPALTGAGIAI-------------- +> +-MYRRILVPLDGSSNSEIIIPYVMAIAAHTPCEIVLATVAHPRQTEFLQHQINES--HKES-MVKNKVLQGKPAEEIVKYADEIEADLVAISSYGFSGQKPPLLGKISIRVLWNTKKPVLLVRS- +> +--MESLLVCIDFSPLTDRIVDTARGMAQCMSRGLHLVHVQPERKEVAMLAKLCKRLQDEGI-RTSCSTPAGRIDEMLTREAREHNAKMVIMGSHGNGAMYHLVVGSVAEGVLSNLGIPVVLVPAQ +> +--STKILICIDFSPLTPRIVKTGKELAKALNLGVHLVHAQPEKKEIKELNNLKSDFEEEDI-PCSYATPRGKTSDVIAAEAAKVEAPYIVLGSHGNGAMYHLVVGSVAEGVMKKLDTPVILVPAQ +> +--MINIVLPVDFGDKSDQLVDGAIQFAKQINGKICVIHVAPTDEELVMLNRVNQKILAHQI-ECEHILKQGIAKDLILEYAESKNADFIVMGSHGRSGIYDVFVGSLTKGITKSSKIPVLVLPI- +> +--MINIVLPVDFGDKTDQLIDGAVKFAKEVNGKICLIHVAPTDEELVLLNKLNQRILAQNV-DCEHILKQGIAKDIILEYADMKNAHYIVMGSHGRSGIYDVFVGSLTKGLTKSSKIPVLVLPI- +> +-NIKKVMACVDLSDYSKMTIDYALSLVKGIDAEVLLLNVINNKTIDSYIEKINDLVNTTEM-KMPILIRAGVPYKEILRAVDKEKVDVVVLGNKGKTNLLGTLHGSHGEKVFRHSPVPVLSVRDR +> +-SLSRIMVALDLSAYSESAFLHALTLAQSLGTELILLNIINSRGRDKYIQELEKEYLQVSA-R--LVFRVGLPYEQILKAVDKEQVDLLVMGTKGRTNIAGALFGTTAEKVFRRANCTVVSVRGP +> +-KIKNMVVALDFSEYSGPILDYAVNIARQTQAGITVLHIINKKPYAEYVARLEAIVKHD-I-SLEIRVEEGIPSVEILKFLKNGDSDFLVIGQKGKSDLPEFIFGAVAEKVFRHSPVPVLSLRLQ +> +-AIRKIVAGIDLSPFSSGILAYAGAISEGAGAEVIAVNVIDRNSSKRFLSDMRELLERH-V-PRSMKIRSGIPFTEVLRVVDEEEADLLVISAKGATNQKRHLLGGTCEKLFRHVPVSVLVLHS- +> +--INRILVSVDLSDTSKAVLNLAKAMSRRHQAELRLLHVITPETEVRRLHQWADSVLGHPM-PYSVECRTGTRTDRLVEAAHEIRADLIIMGAQRPEGLLKYVLGPETYHVIKQAPCPVLTVPEG +> +--IKNILVPTDFSNSAKNALEVGIALAKRHSAQLHILHVIIPQNDKNKLLETSKSIIKHKI-NVVNFIDIGIVSESIEKYASKLHIDLVVMGMNGMRGINEHFVGRNTFQVIKNAICPVFAIPEK +> +--IKNILVPVNFSEASNNALQTAIAMCKRHNATLHLVNVLETEAEEENLANMADAIQNHGL-SCRHYTEAGFIPYVICAKAEELDCDLVVTGTAGTK-VKKIMRVDNAMAILKNCSIPVLIVPSG +> +---MKILVPTDLSENADNALTFAVSYAQQQCASITLIFSYFAVNANSELQKIKER-LGNTV-DIDYKIIQGTVSTAIFSTANNGDFDLIIMGTQGASGIKKNLIGSNTATVIKESAIPVIAVPF- +> +---MKLLVGTDFSENAQNAMDFALQLAKAHNSSITLLFAYTPVQATKELKSLTKKCKKEGI-EIDYLIEQTTPSSAICSVADRESFDLIILGSQGKSDFPSKIFGSTTSEVIRLSSTPVLTVPA- +> +---KTIIAPVDFSDASTNALSFAAELSKRASARLIIVNVQADHKLKSVMSD-LKNAFGPGL-NCESLVTQGSLIAALTEITEAQRPNLIVMGTKGASGLKRILIGSNTVNVIANTKLPVLVIPE- +> +VMFRRILFPTDFSESSFRAFDCVKSFRKAGTEEVIILHVLDEYNARQKAEGMKNTLLESGI-NARIIIVKGVVDKEILSCAQRERASVIVMGRHSSDNLKEIILGTTSERVLKQARMPVLMINE- +> +FMFRKVLFPTDFSEGAYRAVEVFEKRNKMEVGEVILLHVIDEGEASRKLQEKAEEVKRRAK-NVRTIIRFGIPWDEIVKVAEEENVSLIILPSRGKLSLSHEFLGSTVMRVLRKTKKPVLIIKE- +> +PLFEKVLYSTDFSPLAEYAFHYVKRLKSAGMREVVIVHVVNELNVIERAEALEKELKNDGI-SVKLKIISSNAAGQIVKVAEEEKVNIIVIGAHGKGLLAQLILGSVSHDVVRKAKCPVLLVKK- +> +ESIKKILIMVDETPLSQNVVKCGYTLAKQLTAEVALLHVENSKQNMHYLENLSMKF-SDGV-QTKIFVMDGRIKESVLSAAREWNAQLIVAGTHERKGLGRLFKESVSEDILHSSPVPMLIVPE- +> +ELISKILIAVDGSASSEKIVEYGYNMARQIHARVGILMVEDSDVESDFLYRMKSMF-AKGT-PTELFLVKGPVRDVIFDTATAWGAQIIVAGIHHQTGISRFFVSSTADDLLHSTNIPIILVPL- +> +GNMKKIVIAVDNDPTSEKIALSGFQLGLQLKAEIALLSVVDLTDYKKNQQMLVDTV-FKEH-KIWTFVEEGIPYEVILNVAKEWDADIIVLGTHGRTGFSHLIMGSVAEKVIRHSEIPVFIIPT- +> +-MYRKILIPVENSPNDQVILSHIQQLASLTGAKLILICVAHGWRDREYLMALCADLQNRGF-EAEYILAYGEPSDEIIKIAREHEVDLIAMTTHGHRFISDLLYGSVSHDVRHAVDIPVLLLRAK +> +-MYETILVTLDGTPSDRAIIEHVKQLAKLANSRLVLLHVADGWEDTAYLRKVREEFQSTGI-PAEAELAYGEPADQIIKWVEQKGCDLVAMSTHGHRFLADMFLGATASRVRHSIGVPVLLLRAK +> +-MYRKILVALDTGASDLELLPAVTALATLMQSELLLVHVADGWQDLSYLEATAAKLRAESL-TVNILLVLGEPPDQLLKVVAEERIDLIALASHGHRLIGDIIHGSTIDAVRHKATVPLFVVPPK +> +-IYNRILVPIEGTETDAPVLEHVGRLAALCAAEVVLLRVAHYHDAERDLARAAEQLRSRGL-EVRTLLRSGEPQHVIVQQAEELVPDLIAMATHGHGWAKRMVLGSVADHVRHNTDVPLLLLKGR +> +-RYRNILTAIDCSDADMTVIEHVSSLASEPGSVVHLLHVVHSHQAVTLLNGYREKMQADGI-DARVIIRSGEPEDEILSEIEENGYDLLAMATHGHRLPERILFGSVSRTLRKKITIPLLLINSD +> +-VYREILVAIDCSPVDDFLVEQVSALALQLGATLHLLHVVHSHETTRILDQYRQKLEAEGI-GVRVVIRSGEPEQEILREIEERHYDLVAMAAHGHSLPERILFGSVSRTLRQNISIPLLLIKQD +> +-PFSHILLLLDCSLVDHAIIPKIIDMSRCGNGRVTLAHVVHSHKADRFLDPVLKQFRDAGI-NAEKLLLSGEPEKELVKEIGEGDYDLVAMATHGHKTFSDILFGSVSDYLKHETDVPLLMVRGK +> +MEYRIILCPIKTPEISEKGVDAASYLSKLSGARLILLHVVENWEGSKLLNDAEVQARKTGLINVETVLKEGDIAHEIVAEAKKRRADIIVMSTVRHSTIERFFIGSVIDMVTKGAPCPVLWI--- +> +-MFSRILVPIDLEAFSDGALRLAMKDVHDSAAELHLLTIVPGCAAIVELKRFADSRIPDSV-PVSLSVQDGAPAEQILKKARDMEADLIIMAAHNRGGIDGDEMGSTSSKVVAKARCSVVVLRAD +> +-MITRILIPVEDLLFEEEI-REFLIQLSTLAIKLKVLHVIDA-ELVSTICENLKNYFP-GV-DVVSSVREGIVKEEIAKEAESFQADLILMGSHGRKGLGKFLLGSTAKDVIPLSPCSVVLLRTQ +> +-MFKKILVPIDLEAFAEKSMRVAIQQANIHQAALHIITVIPGFTVRVKLEEYVHQNVPGEI-PVTFEVRQGKPHKGILKAAKKFRADLIIMPSHNYKRVEKALIGSCTSRVVAQARVSVMVIKPD +> +-MFNKILVPVDIDKASKAVYDNAAELASLSGAQIRIVSVMPGFIFQKALDDFVAANCK-GA-NVSYKVLVGKHYEEILKMADKWGSDLIVVYHNRNRTVNEAFSSTCAQRVVKEANCSVLRLRNL +> +-MFGKILVPVDLQEFSLNALKLALREIDDGATQLHLITVLPGFEVAQDLNDYAAKYVGAKI-KPILKVIEGSAPEEINRYVAKAGIDLVILRAHQRSKLNEFLLGSVSARVVERACCSVMVLKN- +> +-MFRFILVPVDLNEFADKAVQHALWMAGKCEAKLHLITALPGIAVKSSLQTFAKEKIPESQ-AYSLSVEEGKPYKAIIKTADNLGCDLILMPSHKRSRGNKLLLGSNASKVLENAKVHVMILKH- +> +-MFKKVIFPIDLEGSIEPHLKEIEKIIRYTQAELRVVTVLPGYIAAQELKNFMDQQLASDI-KLSSHIREGRPHEQILAEAKEWQADLIVMPSHIKSK-FSTHIGSVAQRVSERAKCSVLILRA- +> +-MFKKILVPIDLADPATASLKVVKSMVEDMDAEVHILNVAPGYVIREELTKLAAEYLD--T-TPSVSIVTGKRAEKIIHFAEQWQADLIVIGCRAKARGSRHLLGSCSSQVADRAKCNVLVVR-- +> +-MYQHILAPIDVSTIGEQILEKALFHLRYGNADITLLAVAPVKAIRSQLMAFAEHHIAAEG-RIHLKVSQGLPSDQVLKTATDIQAGAIFIGSHRGSQLGRPTLGSTAAKICSQAECDVVVVKAS +> +-PMKNILVATDFSKQAHHAFEAALQLARRAGGSVTLLHVVETPETLKRLKATRQRMLAPGV-PVHDTAAVAEFPEAVARLIQERQIDLLVVGPQEHDTLERFFASTHTEQLIRQATCPVLAVKHA +> +-RFKNVMLSTDFSSCSQHAKRYAYAFAKQPNGILHIAHSVEVTPLREIRSAAQEQLKVAGV-QTKGHLLEGYPPEKIDELALELGCDLLVVGTHGHSGLSHLVHGSTCSKILRSSPAPVLSVKEA +> +--MKNILVATDFSRQAHHAFEAALHLAQRAGGSVTLLHVIDAPEMLKRLEVTHQRMLAPGV-PVHETATVADFPEAIARLIQERQIDLLVVGPQEHDTLERFFASTHTEQLVRQAACPVLAVKHA +> +----------------------------SEQGKITILHVINREETNAYLTKVKNVVEKANL-AVEIVALEGFAATKILDFEKKNPVDFIVIGHHNRKGLDRIVVGSVSKKIIHDAACPVIVVK-- +> +--KRKCVVAVDGSKDSDYALDWFCKNVHREGDHVILVYVPEIHRIRSDLEVFADKLKIHGL-GGRVMSVMSKPGEGILKAAEDENAAMIVVGSRGKSTLRRTFVGSVSDYLVHHATIPVFVCKLI +> +-DFKKILFATDLTNNCRHAFAYAANLATRYEGAITLLHVMESVDAHQALGTFSDTAQNERYVVENILVKDGHVVDTILETAQEEECDLIILGSNKTIFSDSKSLGSRTKSILKRSRIPVMMIPPA +> +-EYNKILYTTDLSESGRYAFHHAASLTNRYGADLTVLHVVEGGEAKECVGQFCEEVQGNPDVSYRVVIKMGDPVNLIIEEAEAGNYDLIIMGSHGHGPLRTAMMGDTVLRVVKRSKIPVLVVRVP +> +-PVTSILFATDLTANCQRAFDFTIDIATRLDATIYMLYVIEKLTARKAIHDFCKQEDMQDFTSREIIISHGDIVAEILSHSQKNECGLIVLGGHKNMFSKT-AVGSTAKRILKKSTIPVTMVPPE +> +-FVSSILFATNLSENCIPAFELAVSLTKKYEARLVLLHVVEDMAARAALDQMCVNAGIDHRICKEVAIGHGDTVDAILVHAQKHGCDMIVLGAKAENQEGEVVVGKTIKGVLRATKIPALVVPAI +> +-EFKTILFTSNLSETSRDAFCHATFLASKLKARIILLHVIEITKAGSALDQFCRDSDMDGIFDYEIVIKEGDVVETIIQQAAEHNCDMIIMGASEGILSG-ATLGGNVKAVLDKAKVPTLVVSMK +> +-SIRKILYTTNLSETGRHAFAYAASLSKLYGSKLTVLHVVDEQEAGECVDRYCSELQDDAAISYDVMVKLGDPVKEIVKVAVEQNYDLIVVGRHRHSKFHDIVHRGTIRSLLDATRLPVFVVQIP +> +-EINKILFVTDLTANAAHAYQYALTMAERFGAAIVVMHVMEGTEAQEALENFCTEVGQAKVTSDAIVITEGRVVDGIIDTCKKQDCDMIVMAHPVRRVIDEPLFGATTRGVLRKSIKPVLLVPPE +> +-PLNAILFATDLTPNCQEAYEFAISQSLRFKAVVYILYIIEAMNALTDIHDFCEITGVGQFQPRELLISAGDIAETIIKNAQENKCDLIVLAARKGIMSRN-LIGNNIKSVLKQSPIPVTIVPTN +> +-KVKKMIFATDLSMGARYAFKHAVDIAVHLNAVITVLHVIENIDAEKTLKQLCTNMQNEPSELVEIEVKYGDTAKLIIDQVENGNCDMIVLAYHYRNLIKEVLPGQVTRKVLKHAKIPILLIPIS +> +--MNKILIPIDFSENAERALAAAKIIAEKDTTQLLILHAYQPYEFQKKLERYIEDVVAEGY-QAEAIWAIGSVQSAVEEAIEAHNPDLIVIGRTGTGGFMDKLIGSSATSIGLHSTCPVLVIPPQ +> +--MKNILYPTDFSLTSRCSIPFLIEFANKTGASIHILNIFSVNSSKENLDLLKKELEGYNQTNLFTISRQGLVVDEILNYVEDNNIDIVVMGTTGASGILEKIIGSNAASVIEKCPKPVLAIPDK +> +--MKNILVATDFTENSRPALETAVYLASRQSATIHLLHTYLPVTYQEQIDKLTEELKARNV-IVTAYLELGPLTPVVKEFTEDKGVDLVIMGRTESGGWFSDLFGNSSTQLFDEIGVPLLVVPGE +> +--MKKIVVATDFQSSSEDAFAYATYLAEQFEAELALVHVYFPIIYETRLAETLASIPNKTL-KTSSKLIIGSVSSGVSGYAEEVGADLIVVGRNHESSFFERLIGSSASDIVKNTSIPVLIVPAA +> +--MRKILVPTDFSAIAANAFQFAQVVAERQNAEVDTMHAYHPSIKRELLDQFIEGNTRDSGSLPKPILNIGFASEE---IVRMKGYDLIIMGTTGEGNFLEKAFGSVSTHVARFAHCPVLLVPGN +> +--MNNILIATDFSDNSHKALQYAILVAKATQSAIYLVHTYLPRLYSK-MVPLASKVEEANI-KCHVVLEMNDVISGVFDTVEKYNIDLIVMGRTGSGGFLSKLIGSNAAHITAKAHIPVLTVPNQ +> +---MKILIGTDFSKASENAIEYTTQIARNFIAEVVLVHSYLPP--DEILEKKVRKLRESGV-RASYKVVIGDLRHAFEEVTKDEPADLIVLGKTENPDFLDKLIGSTSQHLLNQVQVPLLVVPEN +> +--MKTILVPTDFSKSANNALMFAKNLAVNHNYRIKLLHIVQ-TEAKEHNEALQKEIESAGIE-VESVTRRGLIESEILDELTQGNINLIIMGTKGVADLVDKLLGSNASSIIERASCPVLVVPSL +> +-MLKNILYATDLGLFGPFVLEHVCELATKHNARVTVIHAVEPVTIRARVRQAFEEFIDMEC-IQDVLVLDGDACEVILETACSMDADLIVLGS-SGHSDHNTAIGSVASKVLQLSHIPIYLVPT- +> +-NVRKILYATDMGENADIVFRYAISLTHRYNAHLTLVHVTEQLKMQSELEAFCINLKNSHL-VESITVIEGHSPQAIVDYAKTQEIDMIVMGT-EHTALGELFIGSVARRVTQLSAIPVLIVPI- +> +-KINKILYASDIEKGSRPAFRAAISLCGKYESEITYLHVIEPLKIEQRISRFFEEVEFHIS-KVESRIEDGVSWETIIKVADEIDADVIVMGT-THSAMGQFFSGSTANKVMLNTKRPLLIIPL- +> +-EINTIVYATTLGKNTRPVFRHAVNLARQYKARIIMVHALEPVTMQARVAKFRDELDGLGE-LDVQILVDENPAELVLRVAKTEQADLIVIGSSHHGLFGQKLLGDTAQQIGMHTKIPVLMVPN- +> +-EVNTILYACDLEGQTQSALGHVMNLALAHQAKVVVMHVLEPLKMRVLLSDYINDKEAL-H-PPETKIAQGIPYEAIIHVAEKVEADIIVMNS-NHSRFGQMIIGSTANKVIHHSNIPVLVVPI- +> +-DYKTILYASDLGKKTRPVFRTALSMARKYDAQIIMIHVVEPMTMKRRLARFCEEMDSHIN-VKEVLVVSGKTSEEILKAAEKYKVDLVIVGKSTRVILGNDVAGSTARRVSRYANIPVMIVPN- +> +-KIRTILFACDLEPKTNQAMEMALNMAIANQAEIVLMHAIEPVRMQTYLGQFMEAAEEM-A-FPRLELAHGAPAEVIEATAEKVGADLIIMNS-THSRIGQMVIGSTANKVVHHSRVPVMVVPI- +> +-TIKTILYVSDLKGGTWPSMRLACSIAQQYGAKMIYAHVVNHVRMKENVRKFLTDYPESPV-DIQIQVLEGYASQTILRTAELEHADLIVMSS-THGAIGQV-IGSTTNKVMHHGKFPVLVIPY- +> +-QVKTILFACDLEDKTQESLALVMSLAVTQNAKIIFMHAIEPMAMETQITIFYENAAET-E-KPEYLIVQDDASSAIKHAIKDYQVDMVVMNS-THSKLGQMIIGSTANKVIHQSKVPVLVIPL- +> +-----------MRPESKRVFRYAVSLAKQYDAKMLMLYVMEPLEIRQRVTRFYTELEALDV-QIDPLVVEGRHVASILEQAEAHNVDLIVMGN---------RSSQTVNRVVKKSKIPVTVVQM- +> +-----MLWPTDLSPGSQAASAYVDMLASRFDAQVHLLYVATDFRIEEKINNICQNL--SGCPVQIKHIVTGDPAREILEAAETLKVDLIVMATQGSAG--PRFFGSTTEKVVRNAKIPVFTIKPG +> +MAYGTILWATDLSKNSLQAVGHVRELAEAHNARVVALYVGVDLQARHKLEAVCSKL--AACPNLSVRVLPGDPAGEILKAVTAEKADLVVMATRGASKAAGTGLGSVAAKVVAGSSVPVQFVNPN +> +MSVKTILWPTDLSRYSRESIDEVVSLSKLHNSKVVVLYSAIDLKARKTLNKLCDEL--RSCPLIEIRLTLGDPVTNIIEQAEKENADLIVISSHGKNNSAPDVIGSVAEQVIKKSPVSVHVIKNT +> +MNNPKVLWPTDFSRRAEKALPYIATLIREKKADVHILYVIPDISAAKRLNQLCNKL--DGCALFTRHTAVGEPADEILKLIDKEGMDMVVMAGHEPHI--PDIGEPTLEKVKRMASVPVEVIST- +> +-DLKSILCPVDYSDPSKRALKNAIFLSAKLLARLTILAVFEPIRFENEMKEFIREFDLNGI-NHEIVIQTGIVDEKILQSIKEHGYGLLIMGTNGRSGLSRFFMGSITEKVIREVPCSFITTKT- +> +-IPNRVLCPIDFSDESMLALDSAIHLCRLFESELHLIHAVKRIELEVELEDLTDQLDLNGI-TWSKSVILGDPAGAILDVIKNENIDLLMMASSGKGTLKRFFLGSVAERVSRKVPCSFIINKS- +> +-MSQTILVPVDLTAVLDSVFAAVRRQINIEPTKVMLLNVVLGHYVERYTRHARNELTKR-ACEWHIDIELGPVARTIVRYADRVEADLIILASHNPL-VWDVFLGSTAAQVVKHARHSVLVVR-- +> +-MYKKIIVPIAMDEHGESVLGIAVKLIDE-GGEIILLNVVEDLMIEESRKHAVKTLETHGI-NGRVEIRTGGAAGSINALAKEENADLVIIASHRPG-LIDYFIGSTASRVVSHCPCAVLIDR-- +> +-MNRTILVPIDISELTQRVISHVEAEAKIDDAKVHFLTVIPSLYSAELPAMDDLKAEKF-ADRVQAHVAEGSPKDKILEMAKKLPADMVIIASHRPD-ITTYLLGSNAAAXXXXXXXXRAQIN-- +> +-MYKTIVCAVGLGERAEHLVRTAYALLNT-GGILHVAHTVERFWAVSIISEAEEKMSKLVHVHVHVHVRTGRAADTILAIAAEMSADLIVVAAHTPD-VLDHVFGSTVDHIVHHAKCSVHIDR-- +> +-MKNCILVPIDLAANFDLIFSATTTLARRHNAALHLLSVVPTEFVGEAQKLTESQLT---DISWTCEAVIGPIAQTIVRRAIDVGAGLIAIASHDPK-VRDLVLGGTADRVLRRARASVLVLH-- +> +-MYDRVMCAIGLGERAEHLLRTSYALLKP-NGQLTVVHIVERFWAVSVIGEAEEKLNRLI------DVRTGTASKTLLIIAKERKADLIVLATHASD-ILDRIFGSTVEYVIRHAECSVLIDR-- +> +-MYNSILVPIDISDLTRQVIPYVQAHSVLNTARVHFLTVVPTLYSAEMPKLKDFQHAKF-AEKIQTHAVSGAPKDQILNLAKAIDADLIIIASHRPD-ITTYLLGSNAAAVVRHASCPVLVVR-- +> +-SLKHILMPVDLAELVEREVRMALKLLDDDGV-IDILFVDDTALTEK-HSATELAVHDV-QHRGRCIIRNGTVSDEVVAQAKKSNADAIVMASAKPK-FRSYLLGSNAAKIVRHATCSVFVVR-- +> +-MYSRIIVPIAMDEHGEKILERAQSLLDE-GGEIILLNVVEDLLIEASREHAKKTLTEHGVTKGKVEIRIGGAAGIINTFAEEVEGDLVIIASHRPG-LIDYFIGSTASRVASHCKCAVLIDR-- +> +-MYKKIIVPIAMDPQGEATLKRALSLLDA-GGEILMLNVVEDLMLDDSIRHAERTLDQYNV-PGRVLIEVGGASGRIMELAETEKADLVIIASHQPG-LSDYFIGSTASRVAAHCHSAVLIDR-- +> +-MYDSIVIAAALFATTRAALEKAKTLLNP-GGAVTLVHVIEEVHMTTRHREVQEQLDAA-GIKVKAIIRHGQPSASILGAGKEANADLIMIASHKPG-LSDYFIGSTAARVVRHAQCSVLVTR-- +> +-SKETVLVPVDVSHDRSRMFDEVAEHAG-RGAQVVLMTVVPEIMIKAMMDHAAIRLG-T-FEVADQIVRYGPVAPGIIDVAAETGATLIVINARSRD-RTAYLLGSVASRVANHARCSVHVVR-- +> +-KYNNILVPVSFERNAAQALEIADAIRAS-GGRITVLHVLEQLHIDAARATVSGKLAEN-LPDAELVVVEGHSARSILDYAEEHAKDCIVLAGHRPG-MQDLLLGSTAARVVRQASCSVHVVR-- +> +-MAKSILLPIDYSKSWEKALPVAREQAGFYGASLTILTVIPEIYGDGAAEHVKTKIKVQ-CDDLKVEIRQGSVYREILKYAHAEKIEMIVIASAEGD-FPNYEIGPNLARVVRNAHCSVLVIR-- +> +-MYNKILVAMALDISP-QMLEIAQALCNP-GAEIVALHVFEAPAVRDGFDRARQLMAAH-IEGITARIVRGHTYRTLIDYSADHGVDCIVIGSHQPD-FSDYLLGSTAARVVRHAPCAVHVFR-- +> +-MYDNILIPIVFDNDHSQAIECAKRLAGE-NPNITMLSVIELLATEERRVELQHEMDKG-VPGATCEIISGHPGRAIIDYANANGTNLIIVKSHRPG-FQDYFLGSTAAYVVRRAKCAVHVIR-- +> +-MPEHILIPVALDNLARRKLDVARRLLDD-GGRITLLTVLEEIEANNLSENVRSRLRAD-AEDIGIDVISGKAGVRIPEYASKVGVDLIIVGSQKPG-ATGYFLGSTASRIVRRAECAVYVHR-- +> +-MYKKILIALAPDDAAAELKAAARALAD-EGASILALSVIEIVIYEMPREDVERRLES--SPDILRRVEVGNPAATIRHVQETEGCDVVVLRSHSPA-LKDWVLGTTAGRVVRDVNCSIHVLR-- +> +-MFKKILIPIAPDEALDESIGVARALAGP-DTTITALAVLEVIVYERSCKEVYETLKRD-QADVEIRAETGSPASKIVDVVRDEGFDLIVIRSHKPG-LQDWFLGSTAGRVVRHAPCSVHVVR-- +> +LLFENILFANDFSEYSERIWPILADMANHICAPVTLLHVREGRDNMRRLEDLVDSLSGGC-PKVDEEMAEGSPAPRILEIAAERNASLIVIGALGNRTVG-TLLGGVAERVLRESERPVLVLKA- +> +SLFDNILFPTDFSEGAERVIPYLCKITSEMKSPVTIFHVIAETTERFLLDAKRQRILKGCIQGISVELAWGNPGQQICTKAIEGIFSVVIMGSGGKGVTKEFFLGSIAKEVARHADVPVIFIPE- +> +QMSGHILYLTDFSSTAEKALNYVEKLVQETKCPVSILHVQNYEEIQTELQAIKNRLEKAGSTSVDFDFPEGRAIDVVIDIKNKPALSLVVMGSQGKGFVSELFMGSLSLQVTRYSPIPVMLIPA- +> +ELLSHLLFPTDFSQTAAEAMCYLELLAPRGVTRVTLLHALMTLVARNFLDLLQGRLEAAGVPEVETRMAVGHPVAVIVELVKTTDISLIVLGTQGKGFIAEISLGSVAHNISRFAPCPILLIPP- +> +NEMSHVLFPTDFSENAYHAFTYLEKMVEKGLKKVTLMHIQDIAIDRDRLDALRKRLEEKGDVEVEVVLEIGRPFREINRAIDEKHFDLVILGRQGKGIMMDLFIGSNSNNLARRAKTSVLLIPR- +> +RLFTSLLVPYDFSALSALALQKARDIAMVHGCPIRILHVNDNQFDEERLCKLRDALVAEG-LNASYELVEGVVLQEILKRSDPRDTSLIIMGNQGKGFLREAVLGSVANEVARQAEVPVLYVTA- +> +QAFDKILFATDFSQTAQRAGAFLKHILERPRATVNLLYVCDSGLDRQGLEALQRELAAPG-ATFKLECIIGKPAEEIIARTGNDGASLVVMGNHGKGFFREALLGSVANEVARRAEAPVLLVPS- +> +QMLSSVLVPIDVSESSDKLCALACGLAPRGVGRLEMLNVTPFTEAHRKLEALADRARGHGVRHVTTTVLRGQAAELVPERVGSGDYSLVVLAPRCRDVIE-REFGSVASAVLRASQIPLLLAPV- +> +HLFKRTLFATDFSENAERAFRSFEYLRH-ATKEVTLVHVESPKDPQDRLDDLADRLDELE-LDARTEIRRGDPADEILAAEAEHDPSTLMIGSRGRSRLRRLLLGSVSEEVVARATGNVFLVPP- +> +RLLSRVLFPTDLTAVSAMAANYLVRLAPHGLGTVDIVHVVDNTDAQERLAVLEGDLLAAGAAAVTTEVLVGSPERETARRCAMDGHSMIVMAPRCDEDPG-HPLGGVTHAVIQSTHTPVLLIPP- +> +RLLSRVLFPTDFTEASSIAAGYLEQLASHGLGTVNIVHVVDNTDAQEQLAIIAGKLLNAGAATVNTEVLVGSPERETARFCAASTPSMVVMAPRCNEDPG-QPLGGVTHAIIQTAHSPVLLIPP- +> +SLFARVLYAFDFSKQSEELLYYIKRFPI---DELIALHVAESE---DFIEKIKKE-----YPSAKIILKAGKVGKAIVDTAKDFNATLIAIGAGV------EKLGSVTTHVTRNSDVSVLVYK-- +> +KETNRIVIPVDKTEISRMAVEKGVDMAKLLGVDVAIISIDDSREHEAVLEELKKTAETKQV-NAKTEIVGDAPVDEIVKFIN--DDDLIVMATHQKKGLERFVLGSVSEEVLKRVNCNVMILKP- +> +-VFANILLPLDGSLFSEACLKQVSDLARDFKSKLTLLVVIQPPQAQAYLERLTGELQANGI-ETEFRMVSDKIPETILSTAEDINASLISFTTHNRSGIEKWYYGSVAAGLIENSSHPMLLWRN- +> +-KVERILVPLDGSLLAEEALPYARYLGQKTGAEVSIFHSKSS-ELTGYLDRIAAALAEQGA-KTKPVLRGSPPGLEIALEVEERDINLVVMSSHGETGATEGAFGSVASAVLHGSHVPVLIVPC- +> +--MHTILFPTDFSENAYQALVFALKIAAKQQAKLILMNAFPIPRSLEKLQALAKSIRFENL-DIDILSLPGDGVSVIKATARSQHADLIVMGAKGASGLQRFLFGNITADTILFSNIPVLTVPI- +> +MKRMRFLVPVDFSEGSGNAVRYAAALAETASSSVVVLHVVVPPEAQSKLGAWAA---DYNI-EVECKVRVGDVAEETRAMADLMNIDFIIMGTHSVTAVRKLLYGSHTTEVIERVACPVLAIPE- +> +IMYQKIVVALDGSESSRWALYEALQFAQLTQARLHAVYVVHPWDGRLALDEARRAMAERGV-PGDTEIAADDIPHCLARCVQRQGAGLVVMGTQGRHGIGRLLQGSVAETFLRGAHVPVLLVRCP +> +-PISGILVPLDGAGIAASVLPTVASLARPIRAAVHLFAAVDLQRARAYLAALATPLQASGI-ESSYKAHAGDPMTDIVKLARRKHFGLIALSPHSRYAIGRGL-GSVTDRVLHSSPIPVLVTPPQ +> +-LFQRILVPLDGSRLAEAILPAASGLAQACGGELLLLHALERQEASAYLEALARRLTELGL-AARSVVVQQAVADCIARLAAAFAADLVAMTTHGSGGLRGVLFGRIAQQVLQRAERPTLVQRSR +> +-MFKDILLPLDGSKLSEASLDSARYIAKKLKSRITLLHIIEEDEAEEYLKSVARRIIPPGS-MIKVHVHVNDVAASIARHAEEYKSSLIIISSHGKSGIRDFLFGNIAQQIVGRGKTPLLIIKPN +> +DKIKIILAPTDLSEPSQAAVRYALNLARALGAEVTVYHVVNNEELARLLKSYQEHFS-DWV-RIREKVEMGVPEKSIVEWAEKEGSDLIVISMHERSDQTQASGSIVAEKIVRNAPCPVLSVHS- +> +-AIKKIMVALAYSNYSAEEFAYASELATELNSDLVAANVINERDSEVYVKGLAEMIKASAFPRLTILFKVGNPVDELLKIIVVEKVDLVVMGIKGRTDLEYIFIGSVAEKLFQRSPVPIISFRD- +> +-HINRILVATGFSGYAKGLTEYSAKLAANMNAELLVVSVINVRDGEHYAEGLRKILKKAGFPKVKVFIPTGHPVDEILNVALEERADLIVMGTKGRTDLSHVFVGSVADKVFRKSPVTVVSYRT- +> +-EIRKLMVAIEFSENASELFDFAVGLASKLNSDLVAVNVINERSGENYVARLDSLIQETAFPRFKSIFKVGHPTETLIHVAVEEGADMIVAGIKAHTELEHFLVGSVAEKLFRHSPITLVSFRD- +> +-HIKKVMVPVDFSEASKKGVNYGLSLALEFEARLVLANIVRYD-KAHLLDL----IPAELREDFELIVKSGDVRQELLGIVEEKEIDLVVMGSRGRSHVQRLLLGSVTERMLRKLHVPVLTVSH- +> +-DIRKILVPVTFSEFSEELIGYAIDVARPLSAEVVFVNVIDQKDETQYIQELEERLSRINYPKMRIVFKRGRPAAVLLKFAIDERVDLIIMEVKGKSEILHALSGSIAEKIFRYSPVPVLSYRR- +> +-AITRVAVAVNFADYSAELMEYVGDIAERNSAELLAINVIDKRSVENYVEDIEDLFHKTVPADTRAIIRMGIPFEQILKVVEEENIDMVVINSRGRSTFQDFMYGTASEKIFRHCPVPVLSLNL- +> +-KVHTIMVAIDFSKYSQPTAEYAAQMAHDLDADLIFINIINQRQNDQFLTDLDGLIQSCHAERTRGLVRIGLPYQKLLESIDEEKPDLLIMATKGRTDLADVVMGSCARAMYRRSPIPLLSIRG- +> +-KFRKVMVAFDRSEHSADALKYAAQLVKDLDAELSVVSVINQRSVEHYVSIIRKALANTAHAPFKSVFRIGVPFIELVQAIKDEGADLMVMGSKGRSNLAGVLFGTTAEKMFRRCPVPLLSIRE- +> +-MLKKILVPVGFTKHSKGILQLAYDLAKPMSAKLLIANVVHERDGDHYIATLDEYVRDLGISIYDFVLLAGDPTTELLKTVLKEDIDLVVMGTKVK-DIKHIFIGSVAERMFRKCPVPV------ +> +-PTNKVLVATDGSEVGICAAEYAANMAKELGVEVVAIGVINVHEVTGDLNKVREICEGKGV-HCKGIIGYGYPHEEIINYADRESVRMVVIGGSGKDFLGRKMLGSVAEKIVQELPCPVVVIPC- +> +-KARSVAVAIDGSGPSWEAMTRAINMARLLELPLDVLTVIQIRYAKKMLVEAEERGKKAGV-KVQTHLLESGPSEAIVGWLGTRGIKFLVIGSYGHGFRGRHILGSTTERVIRELPVPVLVVPS- +> +-ELKRIMVATDGSKAAEHAVRYAARLAKRRGTELVILHIVSYKAASKIVDAAEALVKEYEV-ACSRVIREALPHLAIVDVLERKDIWVLVLGDKGQDFEDRQTLGSTTHGVLHEIPVPLLVVPY- +> +-PYQNIVVAVDFSLYSKHACKRAIELANYYQASLTLLNVVPEVAAQFQMKAFVNDLD-TDF-PIESKVICGEVNYSIVSFLEAQDVDLAIFGAKKKKGINK-LLGSVAHYVQNHSRCEILIVPV- +> +-EIRSILFATDFSKDAERVEKIVGHWAGRLGAQVEVFHAIRETAAMRRSERVLDRLTQAGV-SCKSKIVYGRASDSILTRAESTGAQLIALGTSGYSAFQRFLLGSVAQRVSRHASCSVLVAGA- \ No newline at end of file diff --git a/esm/source/examples/data/P62593.fasta b/esm/source/examples/data/P62593.fasta new file mode 100644 index 0000000000000000000000000000000000000000..07d71376ce1f8475ba45dc0cc436a6d80411998f --- /dev/null +++ b/esm/source/examples/data/P62593.fasta @@ -0,0 +1,10794 @@ +>0|beta-lactamase_P20P|1.581033423 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1|beta-lactamase_D207D|1.42563125 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2|beta-lactamase_A215A|1.422813331 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3|beta-lactamase_C75C|1.4155315119999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4|beta-lactamase_N134N|1.39696596 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5|beta-lactamase_L137L|1.355533136 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>6|beta-lactamase_L28L|1.3516090040000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>7|beta-lactamase_L199L|1.3516090040000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>8|beta-lactamase_F149F|1.32191175 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>9|beta-lactamase_A200A|1.295473865 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>10|beta-lactamase_E210E|1.29406548 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>11|beta-lactamase_H24H|1.282201552 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>12|beta-lactamase_L19L|1.280029666 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>13|beta-lactamase_A183A|1.279505214 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>14|beta-lactamase_T27T|1.248455477 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>15|beta-lactamase_L38L|1.245034082 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>16|beta-lactamase_I229I|1.23953749 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>17|beta-lactamase_R118R|1.23855076 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>18|beta-lactamase_V214V|1.238463943 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>19|beta-lactamase_P143P|1.237482227 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>20|beta-lactamase_E175E|1.237061839 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>21|beta-lactamase_Y103Y|1.236680537 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>22|beta-lactamase_Q37Q|1.228947143 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>23|beta-lactamase_G142G|1.223102353 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>24|beta-lactamase_T126T|1.213890987 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>25|beta-lactamase_R63R|1.210016568 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>26|beta-lactamase_L223L|1.209258797 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>27|beta-lactamase_K232K|1.204146451 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>28|beta-lactamase_V117V|1.204146451 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>29|beta-lactamase_A133A|1.204146451 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>30|beta-lactamase_A170A|1.204146451 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>31|beta-lactamase_G114G|1.204146451 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>32|beta-lactamase_A123A|1.200392214 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>33|beta-lactamase_Q204Q|1.199645504 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>34|beta-lactamase_G234G|1.195860291 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>35|beta-lactamase_L146L|1.19545104 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>36|beta-lactamase_V101V|1.195300092 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>37|beta-lactamase_G90G|1.189841882 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>38|beta-lactamase_P224P|1.189627145 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>39|beta-lactamase_G154G|1.181999031 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>40|beta-lactamase_A225A|1.179258391 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>41|beta-lactamase_T193T|1.16875245 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>42|beta-lactamase_T179T|1.167976192 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>43|beta-lactamase_I140I|1.165260346 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>44|beta-lactamase_A185A|1.165092705 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>45|beta-lactamase_D113D|1.158658061 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>46|beta-lactamase_S128S|1.1574785159999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>47|beta-lactamase_E61E|1.15497924 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>48|beta-lactamase_A222A|1.154938626 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>49|beta-lactamase_P181P|1.153655812 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>50|beta-lactamase_A246A|1.150079227 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>51|beta-lactamase_R176R|1.149113002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>52|beta-lactamase_V29V|1.142534117 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>53|beta-lactamase_R189R|1.142419155 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>54|beta-lactamase_F58N|1.142207789 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESNRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>55|beta-lactamase_G43G|1.141336861 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>56|beta-lactamase_D155D|1.140947862 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>57|beta-lactamase_R92R|1.137335478 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>58|beta-lactamase_L49L|1.135457842 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>59|beta-lactamase_P217P|1.13381469 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>60|beta-lactamase_A132A|1.132707897 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>61|beta-lactamase_E56E|1.131946574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>62|beta-lactamase_A23A|1.126812329 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>63|beta-lactamase_L10L|1.123508365 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>64|beta-lactamase_T116T|1.122479724 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>65|beta-lactamase_N173N|1.1186516640000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>66|beta-lactamase_G76G|1.117741507 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>67|beta-lactamase_H151H|1.112657025 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>68|beta-lactamase_E166E|1.109622262 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>69|beta-lactamase_A182A|1.109467777 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>70|beta-lactamase_N168N|1.109437862 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>71|beta-lactamase_T112T|1.106795641 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>72|beta-lactamase_R220R|1.102208855 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>73|beta-lactamase_R273R|1.10144642 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>74|beta-lactamase_G52G|1.100669144 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>75|beta-lactamase_F58F|1.100669144 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>76|beta-lactamase_Q88Q|1.100123891 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>77|beta-lactamase_L19W|1.094952121 +MSIQHFRVALIPFFAAFCWPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>78|beta-lactamase_T186T|1.0924468040000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>79|beta-lactamase_S122S|1.092373772 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>80|beta-lactamase_V8V|1.092009091 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>81|beta-lactamase_T178T|1.090003575 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>82|beta-lactamase_A40A|1.088883695 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>83|beta-lactamase_D177D|1.086631569 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>84|beta-lactamase_D174D|1.084439673 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>85|beta-lactamase_V72V|1.082104419 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>86|beta-lactamase_D83D|1.08160189 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>87|beta-lactamase_T139T|1.078124752 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>88|beta-lactamase_K190K|1.077426092 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>89|beta-lactamase_L205L|1.07521716 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>90|beta-lactamase_I45I|1.07460435 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>91|beta-lactamase_A15Y|1.072458669 +MSIQHFRVALIPFFYAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>92|beta-lactamase_T187T|1.072082887 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>93|beta-lactamase_F64F|1.070829876 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>94|beta-lactamase_R202R|1.070247723 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>95|beta-lactamase_I171I|1.069139543 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>96|beta-lactamase_I244I|1.06740524 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>97|beta-lactamase_A182M|1.067029036 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPMAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>98|beta-lactamase_S281F|1.067029036 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAFLIKHW +>99|beta-lactamase_V157K|1.067029036 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHKTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>100|beta-lactamase_A148M|1.067029036 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTMFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>101|beta-lactamase_T186C|1.067029036 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMACTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>102|beta-lactamase_T186W|1.067029036 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAWTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>103|beta-lactamase_S51D|1.067029036 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNDGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>104|beta-lactamase_L196N|1.067029036 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGENLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>105|beta-lactamase_N98Q|1.067029036 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQQDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>106|beta-lactamase_K109Y|1.067029036 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEYHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>107|beta-lactamase_A16M|1.067029036 +MSIQHFRVALIPFFAMFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>108|beta-lactamase_L19Q|1.065112695 +MSIQHFRVALIPFFAAFCQPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>109|beta-lactamase_L19A|1.064585721 +MSIQHFRVALIPFFAAFCAPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>110|beta-lactamase_V8S|1.062300049 +MSIQHFRSALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>111|beta-lactamase_Y103W|1.0618851740000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEWSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>112|beta-lactamase_N50N|1.061565115 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>113|beta-lactamase_T262Y|1.060920749 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTYGSQATMDERNRQIAEIGASLIKHW +>114|beta-lactamase_I206I|1.05990302 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>115|beta-lactamase_K190D|1.0596529609999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRDLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>116|beta-lactamase_F6F|1.059540238 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>117|beta-lactamase_T112Q|1.059511151 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLQDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>118|beta-lactamase_P172P|1.05927624 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>119|beta-lactamase_P65P|1.058995065 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>120|beta-lactamase_S122M|1.058884685 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCMAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>121|beta-lactamase_A211D|1.058530502 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEDDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>122|beta-lactamase_V29N|1.055182672 +MSIQHFRVALIPFFAAFCLPVFAHPETLNKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>123|beta-lactamase_Q274T|1.054812461 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRTIAEIGASLIKHW +>124|beta-lactamase_L196K|1.054812461 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEKLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>125|beta-lactamase_L19K|1.054812461 +MSIQHFRVALIPFFAAFCKPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>126|beta-lactamase_L160L|1.053874348 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>127|beta-lactamase_I171N|1.053548681 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEANPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>128|beta-lactamase_L199I|1.05306725 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTIASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>129|beta-lactamase_Q97F|1.05306725 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSFNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>130|beta-lactamase_Y44Y|1.052278813 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>131|beta-lactamase_C121C|1.0517263890000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>132|beta-lactamase_L19C|1.051597547 +MSIQHFRVALIPFFAAFCCPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>133|beta-lactamase_V29W|1.050740237 +MSIQHFRVALIPFFAAFCLPVFAHPETLWKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>134|beta-lactamase_L192L|1.050530784 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>135|beta-lactamase_S233S|1.048897879 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>136|beta-lactamase_Q97Y|1.048704173 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSYNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>137|beta-lactamase_F13M|1.048704173 +MSIQHFRVALIPMFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>138|beta-lactamase_V8Y|1.048113086 +MSIQHFRYALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>139|beta-lactamase_P60D|1.048065979 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRDEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>140|beta-lactamase_A280M|1.047482516 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGMSLIKHW +>141|beta-lactamase_D33T|1.047482516 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKTAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>142|beta-lactamase_L196Q|1.047482516 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEQLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>143|beta-lactamase_A225M|1.047482516 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPMGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>144|beta-lactamase_H156I|1.047482516 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDIVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>145|beta-lactamase_H24N|1.047482516 +MSIQHFRVALIPFFAAFCLPVFANPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>146|beta-lactamase_L47L|1.04717842 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>147|beta-lactamase_A15T|1.04666811 +MSIQHFRVALIPFFTAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>148|beta-lactamase_E237M|1.046260858 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGMRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>149|beta-lactamase_H94I|1.045870416 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIIYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>150|beta-lactamase_T193K|1.045310702 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLKGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>151|beta-lactamase_D36K|1.045310702 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEKQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>152|beta-lactamase_L199G|1.045310702 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTGASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>153|beta-lactamase_T186E|1.044739161 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAETLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>154|beta-lactamase_K213A|1.044182477 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADAVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>155|beta-lactamase_D33H|1.044033141 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKHAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>156|beta-lactamase_N152Q|1.043573211 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHQMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>157|beta-lactamase_A16G|1.043573211 +MSIQHFRVALIPFFAGFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>158|beta-lactamase_L19T|1.043384099 +MSIQHFRVALIPFFAAFCTPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>159|beta-lactamase_R273K|1.042595885 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNKQIAEIGASLIKHW +>160|beta-lactamase_N98F|1.042595885 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQFDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>161|beta-lactamase_N173M|1.042595885 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPMDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>162|beta-lactamase_L19N|1.042595885 +MSIQHFRVALIPFFAAFCNPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>163|beta-lactamase_R202K|1.041897781 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASKQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>164|beta-lactamase_L196Y|1.041533532 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEYLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>165|beta-lactamase_T186M|1.04130992 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAMTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>166|beta-lactamase_D33Q|1.04115863 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKQAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>167|beta-lactamase_S122E|1.040966976 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCEAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>168|beta-lactamase_A182L|1.040374717 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPLAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>169|beta-lactamase_L199C|1.040374717 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTCASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>170|beta-lactamase_N152H|1.039881069 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHHMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>171|beta-lactamase_T112K|1.039792035 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLKDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>172|beta-lactamase_N152D|1.039663907 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHDMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>173|beta-lactamase_A15C|1.039541742 +MSIQHFRVALIPFFCAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>174|beta-lactamase_G39E|1.039408923 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLEARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>175|beta-lactamase_D250Q|1.039105463 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPQGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>176|beta-lactamase_L19S|1.039105463 +MSIQHFRVALIPFFAAFCSPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>177|beta-lactamase_L199V|1.038836894 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTVASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>178|beta-lactamase_K30C|1.038523661 +MSIQHFRVALIPFFAAFCLPVFAHPETLVCVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>179|beta-lactamase_L19F|1.038424365 +MSIQHFRVALIPFFAAFCFPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>180|beta-lactamase_L19Y|1.038424365 +MSIQHFRVALIPFFAAFCYPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>181|beta-lactamase_Y260F|1.038284118 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIFTTGSQATMDERNRQIAEIGASLIKHW +>182|beta-lactamase_R118W|1.038071257 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVWELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>183|beta-lactamase_Q203Q|1.037941308 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>184|beta-lactamase_G194G|1.037941308 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>185|beta-lactamase_T261M|1.03791723 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTGSQATMDERNRQIAEIGASLIKHW +>186|beta-lactamase_R118H|1.037709255 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVHELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>187|beta-lactamase_T193V|1.036957496 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLVGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>188|beta-lactamase_T193Y|1.036957496 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLYGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>189|beta-lactamase_E102D|1.036957496 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVDYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>190|beta-lactamase_D33A|1.03674571 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKAAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>191|beta-lactamase_P60A|1.036274052 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRAEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>192|beta-lactamase_L49M|1.036166155 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDMNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>193|beta-lactamase_K32Q|1.035932281 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVQDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>194|beta-lactamase_I171E|1.03545388 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAEPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>195|beta-lactamase_T138V|1.035332007 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLVTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>196|beta-lactamase_D36G|1.035297703 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEGQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>197|beta-lactamase_V8K|1.03526594 +MSIQHFRKALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>198|beta-lactamase_P20Q|1.035116312 +MSIQHFRVALIPFFAAFCLQVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>199|beta-lactamase_A15G|1.034966585 +MSIQHFRVALIPFFGAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>200|beta-lactamase_A16S|1.034960526 +MSIQHFRVALIPFFASFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>201|beta-lactamase_D36R|1.034848817 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAERQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>202|beta-lactamase_S104S|1.034734664 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>203|beta-lactamase_L19V|1.034685897 +MSIQHFRVALIPFFAAFCVPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>204|beta-lactamase_Q274W|1.034451534 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRWIAEIGASLIKHW +>205|beta-lactamase_V157D|1.034451534 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHDTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>206|beta-lactamase_I171H|1.034451534 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAHPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>207|beta-lactamase_I171Q|1.034451534 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAQPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>208|beta-lactamase_T193A|1.034451534 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLAGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>209|beta-lactamase_L196H|1.034451534 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEHLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>210|beta-lactamase_S2H|1.034451534 +MHIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>211|beta-lactamase_D129D|1.03412852 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>212|beta-lactamase_Q265S|1.033758317 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSSATMDERNRQIAEIGASLIKHW +>213|beta-lactamase_A200H|1.033433454 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLHSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>214|beta-lactamase_T139E|1.033328098 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTEIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>215|beta-lactamase_E237P|1.033244928 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGPRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>216|beta-lactamase_N50D|1.033198505 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLDSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>217|beta-lactamase_G141G|1.033150391 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>218|beta-lactamase_A200N|1.033121785 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLNSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>219|beta-lactamase_T138R|1.033065197 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLRTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>220|beta-lactamase_V8F|1.032822625 +MSIQHFRFALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>221|beta-lactamase_T138Q|1.032535194 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLQTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>222|beta-lactamase_Q97E|1.032535194 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSENDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>223|beta-lactamase_R118A|1.032220201 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVAELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>224|beta-lactamase_L196I|1.032124521 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEILTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>225|beta-lactamase_Q37Y|1.032124521 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDYLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>226|beta-lactamase_H94H|1.031828896 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>227|beta-lactamase_L196R|1.031736718 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGERLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>228|beta-lactamase_L196T|1.031678958 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGETLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>229|beta-lactamase_T112Y|1.031489943 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLYDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>230|beta-lactamase_F22E|1.031489943 +MSIQHFRVALIPFFAAFCLPVEAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>231|beta-lactamase_S122D|1.031193716 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCDAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>232|beta-lactamase_R202Q|1.030773368 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASQQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>233|beta-lactamase_A280E|1.030728313 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGESLIKHW +>234|beta-lactamase_A225Q|1.030728313 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPQGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>235|beta-lactamase_T138N|1.030663419 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLNTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>236|beta-lactamase_A15S|1.030447527 +MSIQHFRVALIPFFSAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>237|beta-lactamase_S122L|1.03037931 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCLAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>238|beta-lactamase_A15F|1.03037931 +MSIQHFRVALIPFFFAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>239|beta-lactamase_I54P|1.03022069 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKPLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>240|beta-lactamase_I171A|1.030202219 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAAPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>241|beta-lactamase_L199P|1.030148857 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTPASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>242|beta-lactamase_F58Y|1.029797606 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESYRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>243|beta-lactamase_G194T|1.029660682 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTTELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>244|beta-lactamase_I54V|1.029660682 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKVLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>245|beta-lactamase_P60G|1.029564904 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRGEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>246|beta-lactamase_D207A|1.029526984 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIAWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>247|beta-lactamase_E102Q|1.029439611 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVQYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>248|beta-lactamase_K284E|1.029239064 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIEHW +>249|beta-lactamase_A182I|1.029197039 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPIAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>250|beta-lactamase_R41K|1.029197039 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAKVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>251|beta-lactamase_T138K|1.029132731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLKTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>252|beta-lactamase_T186F|1.029021902 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAFTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>253|beta-lactamase_Q265K|1.029021902 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSKATMDERNRQIAEIGASLIKHW +>254|beta-lactamase_R118Y|1.028889474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVYELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>255|beta-lactamase_N173W|1.028785878 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPWDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>256|beta-lactamase_T193S|1.028450362 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLSGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>257|beta-lactamase_H24A|1.028343247 +MSIQHFRVALIPFFAAFCLPVFAAPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>258|beta-lactamase_L19I|1.028223427 +MSIQHFRVALIPFFAAFCIPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>259|beta-lactamase_M180Q|1.027935995 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTQPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>260|beta-lactamase_H156K|1.027935995 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDKVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>261|beta-lactamase_N50M|1.027935995 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLMSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>262|beta-lactamase_S122N|1.02762071 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCNAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>263|beta-lactamase_Q97R|1.027307281 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSRNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>264|beta-lactamase_S68S|1.027290257 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>265|beta-lactamase_Q274L|1.027164396 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRLIAEIGASLIKHW +>266|beta-lactamase_W163F|1.027047508 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRFEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>267|beta-lactamase_A182V|1.027009197 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>268|beta-lactamase_H285T|1.026864943 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKTW +>269|beta-lactamase_L192I|1.026786171 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLITGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>270|beta-lactamase_D207S|1.026786171 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLISWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>271|beta-lactamase_T112W|1.026786171 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLWDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>272|beta-lactamase_A15M|1.026726945 +MSIQHFRVALIPFFMAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>273|beta-lactamase_T138A|1.026521413 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLATIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>274|beta-lactamase_A200D|1.02651594 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLDSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>275|beta-lactamase_R41H|1.026505776 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAHVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>276|beta-lactamase_H151W|1.026307086 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLWNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>277|beta-lactamase_R118N|1.026307086 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVNELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>278|beta-lactamase_T112E|1.026307086 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLEDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>279|beta-lactamase_V29G|1.026236327 +MSIQHFRVALIPFFAAFCLPVFAHPETLGKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>280|beta-lactamase_M180S|1.025999814 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTSPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>281|beta-lactamase_S201H|1.02587843 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAHRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>282|beta-lactamase_N152E|1.02587843 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHEMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>283|beta-lactamase_A222C|1.02568062 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSCLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>284|beta-lactamase_D269E|1.025616898 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMEERNRQIAEIGASLIKHW +>285|beta-lactamase_N98T|1.025616898 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQTDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>286|beta-lactamase_A246M|1.025566761 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAMLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>287|beta-lactamase_K30T|1.025566761 +MSIQHFRVALIPFFAAFCLPVFAHPETLVTVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>288|beta-lactamase_Q37K|1.025566761 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>289|beta-lactamase_Q97V|1.025313927 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSVNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>290|beta-lactamase_T138E|1.025143677 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLETIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>291|beta-lactamase_Q37N|1.025143677 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDNLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>292|beta-lactamase_A222R|1.02502112 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSRLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>293|beta-lactamase_T193N|1.02486983 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLNGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>294|beta-lactamase_D36A|1.02486983 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEAQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>295|beta-lactamase_T112R|1.02486983 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLRDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>296|beta-lactamase_Q86S|1.024853997 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGSEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>297|beta-lactamase_I283Y|1.0246168 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLYKHW +>298|beta-lactamase_E145N|1.024536562 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKNLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>299|beta-lactamase_Q37V|1.024536562 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDVLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>300|beta-lactamase_N152R|1.024536562 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHRMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>301|beta-lactamase_E145G|1.024461014 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKGLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>302|beta-lactamase_T112L|1.024427688 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLLDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>303|beta-lactamase_A182F|1.024271022 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPFAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>304|beta-lactamase_H151K|1.024271022 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLKNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>305|beta-lactamase_F22H|1.024271022 +MSIQHFRVALIPFFAAFCLPVHAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>306|beta-lactamase_M180E|1.024122078 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTEPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>307|beta-lactamase_E237S|1.024122078 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGSRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>308|beta-lactamase_H285F|1.024026691 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKFW +>309|beta-lactamase_V21C|1.023990823 +MSIQHFRVALIPFFAAFCLPCFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>310|beta-lactamase_N98L|1.023844908 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQLDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>311|beta-lactamase_T131G|1.023770338 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNGAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>312|beta-lactamase_A16V|1.023747469 +MSIQHFRVALIPFFAVFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>313|beta-lactamase_E46E|1.0235926990000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>314|beta-lactamase_L55M|1.023592367 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIMESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>315|beta-lactamase_D33R|1.023592367 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKRAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>316|beta-lactamase_Q203E|1.023592367 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASREQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>317|beta-lactamase_L199E|1.023592367 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTEASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>318|beta-lactamase_G90E|1.023445573 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLERRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>319|beta-lactamase_L196S|1.023445573 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGESLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>320|beta-lactamase_R118E|1.023425244 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVEELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>321|beta-lactamase_S281A|1.023282066 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAALIKHW +>322|beta-lactamase_D36L|1.023217856 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAELQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>323|beta-lactamase_R238N|1.023217856 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGENGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>324|beta-lactamase_T193G|1.022816663 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLGGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>325|beta-lactamase_T193R|1.02274395 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLRGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>326|beta-lactamase_I171M|1.02260517 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAMPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>327|beta-lactamase_G90K|1.02260517 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLKRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>328|beta-lactamase_G39K|1.02260517 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLKARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>329|beta-lactamase_K32M|1.02260517 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVMDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>330|beta-lactamase_H156A|1.02260517 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDAVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>331|beta-lactamase_F17V|1.02260517 +MSIQHFRVALIPFFAAVCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>332|beta-lactamase_L19H|1.02260517 +MSIQHFRVALIPFFAAFCHPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>333|beta-lactamase_H24K|1.022449287 +MSIQHFRVALIPFFAAFCLPVFAKPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>334|beta-lactamase_S254Q|1.022375303 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPQRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>335|beta-lactamase_S80Y|1.022251183 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLYRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>336|beta-lactamase_L196A|1.0222349590000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEALTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>337|beta-lactamase_A9S|1.0222349590000002 +MSIQHFRVSLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>338|beta-lactamase_A225P|1.022082496 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPPGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>339|beta-lactamase_L192M|1.021921726 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLMTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>340|beta-lactamase_M153C|1.021921726 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNCGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>341|beta-lactamase_M153W|1.021921726 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNWGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>342|beta-lactamase_I206Y|1.021921726 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLYDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>343|beta-lactamase_E61G|1.021921726 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPGERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>344|beta-lactamase_H5M|1.021921726 +MSIQMFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>345|beta-lactamase_R189Y|1.021653157 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLYKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>346|beta-lactamase_A15W|1.021572039 +MSIQHFRVALIPFFWAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>347|beta-lactamase_A148R|1.021532848 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTRFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>348|beta-lactamase_A222K|1.021420455 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSKLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>349|beta-lactamase_N50G|1.021420455 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLGSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>350|beta-lactamase_K144E|1.021420455 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPEELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>351|beta-lactamase_K144S|1.021323211 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPSELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>352|beta-lactamase_A280Q|1.021037246 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGQSLIKHW +>353|beta-lactamase_D33Y|1.021037246 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKYAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>354|beta-lactamase_R118S|1.021037246 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVSELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>355|beta-lactamase_T112D|1.021037246 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLDDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>356|beta-lactamase_N98E|1.021037246 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQEDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>357|beta-lactamase_H24T|1.021037246 +MSIQHFRVALIPFFAAFCLPVFATPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>358|beta-lactamase_G251N|1.020877551 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDNKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>359|beta-lactamase_N173L|1.020877551 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPLDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>360|beta-lactamase_S281V|1.0207346659999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAVLIKHW +>361|beta-lactamase_A280K|1.0207346659999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGKSLIKHW +>362|beta-lactamase_I171V|1.0207346659999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAVPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>363|beta-lactamase_M180T|1.020668696 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>364|beta-lactamase_T186L|1.020623642 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMALTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>365|beta-lactamase_E108E|1.02057291 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>366|beta-lactamase_M67A|1.0205349 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMASTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>367|beta-lactamase_E61H|1.0205349 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPHERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>368|beta-lactamase_I171L|1.020527277 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEALPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>369|beta-lactamase_T139A|1.020489748 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTAIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>370|beta-lactamase_H24V|1.020287344 +MSIQHFRVALIPFFAAFCLPVFAVPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>371|beta-lactamase_P20D|1.020287344 +MSIQHFRVALIPFFAAFCLDVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>372|beta-lactamase_E166W|1.020227531 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPWLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>373|beta-lactamase_R41R|1.020220409 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>374|beta-lactamase_N152Y|1.020117387 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHYMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>375|beta-lactamase_E166Y|1.020066663 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPYLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>376|beta-lactamase_R92V|1.020031968 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRVIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>377|beta-lactamase_A225N|1.020018384 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPNGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>378|beta-lactamase_R118G|1.020006753 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>379|beta-lactamase_I206L|1.019972645 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLLDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>380|beta-lactamase_E210I|1.019972645 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMIADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>381|beta-lactamase_A148S|1.019953685 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTSFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>382|beta-lactamase_S254A|1.019928958 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPARIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>383|beta-lactamase_Q37A|1.019907946 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDALGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>384|beta-lactamase_L247M|1.019739064 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAMGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>385|beta-lactamase_E270D|1.019739064 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDDRNRQIAEIGASLIKHW +>386|beta-lactamase_D36W|1.019739064 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEWQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>387|beta-lactamase_E237G|1.01965257 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGGRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>388|beta-lactamase_D36T|1.019558943 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAETQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>389|beta-lactamase_N173Q|1.019558943 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPQDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>390|beta-lactamase_L196E|1.019415764 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEELTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>391|beta-lactamase_Q97M|1.019354584 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSMNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>392|beta-lactamase_V21A|1.019326241 +MSIQHFRVALIPFFAAFCLPAFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>393|beta-lactamase_S57A|1.019273368 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEAFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>394|beta-lactamase_A148N|1.019140061 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTNFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>395|beta-lactamase_A9T|1.019005287 +MSIQHFRVTLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>396|beta-lactamase_K53T|1.018920358 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGTILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>397|beta-lactamase_D250N|1.018870905 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPNGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>398|beta-lactamase_Q88H|1.018829857 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEHLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>399|beta-lactamase_T186I|1.018646511 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAITLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>400|beta-lactamase_E166S|1.018550538 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPSLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>401|beta-lactamase_K190E|1.018499717 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRELLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>402|beta-lactamase_E237A|1.018484177 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGARGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>403|beta-lactamase_E175P|1.018448505 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDPRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>404|beta-lactamase_E175V|1.018424951 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDVRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>405|beta-lactamase_L47I|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEIDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>406|beta-lactamase_E46S|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYISLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>407|beta-lactamase_S281Y|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAYLIKHW +>408|beta-lactamase_Q204M|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQMLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>409|beta-lactamase_V101T|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLTEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>410|beta-lactamase_G251H|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDHKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>411|beta-lactamase_R202T|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASTQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>412|beta-lactamase_D33C|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKCAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>413|beta-lactamase_E119Q|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRQLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>414|beta-lactamase_V29Q|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLQKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>415|beta-lactamase_D36F|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEFQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>416|beta-lactamase_T138H|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLHTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>417|beta-lactamase_A225K|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPKGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>418|beta-lactamase_Q37D|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDDLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>419|beta-lactamase_L199N|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTNASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>420|beta-lactamase_H156G|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDGVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>421|beta-lactamase_E102P|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVPYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>422|beta-lactamase_N98R|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQRDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>423|beta-lactamase_K109M|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEMHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>424|beta-lactamase_K144D|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPDELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>425|beta-lactamase_E195N|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGNLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>426|beta-lactamase_Q265G|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSGATMDERNRQIAEIGASLIKHW +>427|beta-lactamase_Q265H|1.018162735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSHATMDERNRQIAEIGASLIKHW +>428|beta-lactamase_A16L|1.018162735 +MSIQHFRVALIPFFALFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>429|beta-lactamase_S2I|1.018162735 +MIIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>430|beta-lactamase_A200S|1.017789689 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLSSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>431|beta-lactamase_R238H|1.017609568 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEHGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>432|beta-lactamase_E175M|1.017587871 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDMRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>433|beta-lactamase_V8T|1.017474502 +MSIQHFRTALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>434|beta-lactamase_A200Q|1.017433356 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLQSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>435|beta-lactamase_K53N|1.017387031 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGNILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>436|beta-lactamase_N173D|1.017374521 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPDDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>437|beta-lactamase_R189Q|1.017334451 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLQKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>438|beta-lactamase_K144A|1.017257828 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPAELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>439|beta-lactamase_I45V|1.017240725 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYVELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>440|beta-lactamase_V106I|1.017223036 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPITEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>441|beta-lactamase_R238M|1.017123055 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEMGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>442|beta-lactamase_T186V|1.017060506 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAVTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>443|beta-lactamase_E166D|1.017060506 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPDLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>444|beta-lactamase_H156Y|1.0170263000000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDYVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>445|beta-lactamase_D36I|1.016909705 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEIQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>446|beta-lactamase_A9P|1.016841976 +MSIQHFRVPLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>447|beta-lactamase_S2N|1.016766527 +MNIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>448|beta-lactamase_A148D|1.016731538 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTDFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>449|beta-lactamase_A23G|1.016725479 +MSIQHFRVALIPFFAAFCLPVFGHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>450|beta-lactamase_A211A|1.016651251 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>451|beta-lactamase_S281E|1.016586405 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAELIKHW +>452|beta-lactamase_A182R|1.016522879 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPRAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>453|beta-lactamase_Q265A|1.016417523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSAATMDERNRQIAEIGASLIKHW +>454|beta-lactamase_G194S|1.016374912 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTSELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>455|beta-lactamase_E237N|1.0163528240000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGNRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>456|beta-lactamase_A148E|1.016318716 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTEFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>457|beta-lactamase_V8N|1.016283239 +MSIQHFRNALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>458|beta-lactamase_M66V|1.016275225 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPVMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>459|beta-lactamase_M184I|1.0162463940000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAIATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>460|beta-lactamase_A182Y|1.016208082 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPYAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>461|beta-lactamase_S254K|1.016154525 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPKRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>462|beta-lactamase_E61Q|1.016126671 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPQERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>463|beta-lactamase_K144N|1.016126671 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPNELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>464|beta-lactamase_D33V|1.016038125 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKVAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>465|beta-lactamase_A84N|1.016038125 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDNGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>466|beta-lactamase_N98A|1.016038125 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQADLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>467|beta-lactamase_K252E|1.015705737 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGEPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>468|beta-lactamase_A211Q|1.015590803 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEQDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>469|beta-lactamase_I171W|1.015590803 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAWPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>470|beta-lactamase_S51T|1.015590803 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNTGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>471|beta-lactamase_Q203M|1.015590803 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRMQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>472|beta-lactamase_A9Y|1.015590803 +MSIQHFRVYLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>473|beta-lactamase_V106L|1.015521315 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPLTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>474|beta-lactamase_E61M|1.015497273 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPMERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>475|beta-lactamase_Q265L|1.015447918 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSLATMDERNRQIAEIGASLIKHW +>476|beta-lactamase_K144G|1.015335721 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPGELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>477|beta-lactamase_L49F|1.015288223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDFNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>478|beta-lactamase_A280I|1.015288223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGISLIKHW +>479|beta-lactamase_Q203H|1.015288223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRHQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>480|beta-lactamase_D250H|1.015288223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPHGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>481|beta-lactamase_E166F|1.015170944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPFLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>482|beta-lactamase_N152S|1.015170944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHSMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>483|beta-lactamase_Q203R|1.015123251 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRRQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>484|beta-lactamase_V29A|1.015108591 +MSIQHFRVALIPFFAAFCLPVFAHPETLAKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>485|beta-lactamase_H156D|1.015108591 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDDVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>486|beta-lactamase_K284T|1.01508103 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLITHW +>487|beta-lactamase_N98S|1.015069889 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQSDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>488|beta-lactamase_E175T|1.015065588 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDTRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>489|beta-lactamase_S281T|1.0150245409999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGATLIKHW +>490|beta-lactamase_A182K|1.014975772 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPKAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>491|beta-lactamase_R238C|1.014920455 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGECGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>492|beta-lactamase_T27V|1.014905014 +MSIQHFRVALIPFFAAFCLPVFAHPEVLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>493|beta-lactamase_S254C|1.014905014 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPCRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>494|beta-lactamase_E210V|1.014905014 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMVADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>495|beta-lactamase_D36V|1.014905014 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEVQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>496|beta-lactamase_E26L|1.014905014 +MSIQHFRVALIPFFAAFCLPVFAHPLTLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>497|beta-lactamase_N50P|1.014905014 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLPSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>498|beta-lactamase_E195H|1.014905014 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGHLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>499|beta-lactamase_E61D|1.014805522 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPDERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>500|beta-lactamase_A266L|1.014792621 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQLTMDERNRQIAEIGASLIKHW +>501|beta-lactamase_Q204E|1.014792621 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQELIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>502|beta-lactamase_Q86V|1.014792621 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGVEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>503|beta-lactamase_P12I|1.014707496 +MSIQHFRVALIIFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>504|beta-lactamase_R176K|1.014672312 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEKDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>505|beta-lactamase_K284D|1.014672312 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIDHW +>506|beta-lactamase_N152T|1.014587187 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHTMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>507|beta-lactamase_A15L|1.014543012 +MSIQHFRVALIPFFLAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>508|beta-lactamase_M180C|1.014497762 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTCPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>509|beta-lactamase_V42F|1.014403743 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARFGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>510|beta-lactamase_S281K|1.014403743 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAKLIKHW +>511|beta-lactamase_A222Q|1.014403743 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSQLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>512|beta-lactamase_P217K|1.014403743 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGKLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>513|beta-lactamase_N50E|1.014403743 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLESGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>514|beta-lactamase_V8C|1.014403743 +MSIQHFRCALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>515|beta-lactamase_I206M|1.014304838 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLMDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>516|beta-lactamase_A246L|1.01425343 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIALLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>517|beta-lactamase_K190T|1.014200557 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRTLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>518|beta-lactamase_L219I|1.014173681 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLIRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>519|beta-lactamase_R92I|1.014157262 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRIIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>520|beta-lactamase_F22W|1.01409051 +MSIQHFRVALIPFFAAFCLPVWAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>521|beta-lactamase_F149W|1.013974208 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAWLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>522|beta-lactamase_Q204L|1.013974208 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQLLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>523|beta-lactamase_E237Q|1.013876183 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGQRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>524|beta-lactamase_I3N|1.013819107 +MSNQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>525|beta-lactamase_Q86I|1.013773563 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGIEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>526|beta-lactamase_E145A|1.013760369 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKALTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>527|beta-lactamase_T193M|1.013720299 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLMGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>528|beta-lactamase_D207E|1.013720299 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIEWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>529|beta-lactamase_D36C|1.013720299 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAECQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>530|beta-lactamase_I3K|1.013720299 +MSKQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>531|beta-lactamase_Q4E|1.013720299 +MSIEHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>532|beta-lactamase_S96S|1.01359188 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>533|beta-lactamase_K190N|1.0135815190000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRNLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>534|beta-lactamase_N98K|1.013508806 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQKDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>535|beta-lactamase_D207Y|1.013433747 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIYWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>536|beta-lactamase_T186R|1.013395338 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMARTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>537|beta-lactamase_T112I|1.013276104 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLIDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>538|beta-lactamase_K252H|1.013276104 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGHPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>539|beta-lactamase_Q4N|1.013276104 +MSINHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>540|beta-lactamase_S254T|1.013176417 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPTRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>541|beta-lactamase_A225T|1.013072527 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPTGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>542|beta-lactamase_S96N|1.013018872 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYNQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>543|beta-lactamase_A15V|1.012988673 +MSIQHFRVALIPFFVAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>544|beta-lactamase_T267P|1.012944009 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAPMDERNRQIAEIGASLIKHW +>545|beta-lactamase_N173E|1.0129271009999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPEDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>546|beta-lactamase_L47V|1.012900225 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEVDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>547|beta-lactamase_N173G|1.012889376 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPGDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>548|beta-lactamase_M180K|1.0128798959999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTKPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>549|beta-lactamase_G90D|1.0128639659999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLDRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>550|beta-lactamase_K109R|1.01284569 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTERHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>551|beta-lactamase_P217A|1.012840706 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGALLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>552|beta-lactamase_A230C|1.012733102 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFICDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>553|beta-lactamase_T262H|1.012733102 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTHGSQATMDERNRQIAEIGASLIKHW +>554|beta-lactamase_V106E|1.012733102 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPETEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>555|beta-lactamase_A211R|1.012733102 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMERDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>556|beta-lactamase_I171K|1.012733102 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAKPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>557|beta-lactamase_D33K|1.012733102 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKKAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>558|beta-lactamase_P217M|1.012733102 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGMLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>559|beta-lactamase_A200E|1.012733102 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLESRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>560|beta-lactamase_V29I|1.012733102 +MSIQHFRVALIPFFAAFCLPVFAHPETLIKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>561|beta-lactamase_H151A|1.012733102 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLANMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>562|beta-lactamase_Q37L|1.012733102 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDLLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>563|beta-lactamase_N98H|1.012733102 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQHDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>564|beta-lactamase_R7Q|1.012733102 +MSIQHFQVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>565|beta-lactamase_L100L|1.012592475 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>566|beta-lactamase_T112S|1.012578 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLSDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>567|beta-lactamase_E270T|1.012524345 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDTRNRQIAEIGASLIKHW +>568|beta-lactamase_P12M|1.0124805609999998 +MSIQHFRVALIMFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>569|beta-lactamase_D250E|1.012473817 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPEGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>570|beta-lactamase_I171G|1.012375889 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAGPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>571|beta-lactamase_E26T|1.012298778 +MSIQHFRVALIPFFAAFCLPVFAHPTTLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>572|beta-lactamase_E108V|1.012298778 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTVKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>573|beta-lactamase_T186A|1.012265061 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAATLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>574|beta-lactamase_I171T|1.012239552 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEATPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>575|beta-lactamase_E145K|1.012239552 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKKLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>576|beta-lactamase_K53A|1.012225674 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGAILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>577|beta-lactamase_K109S|1.012225674 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTESHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>578|beta-lactamase_K213Q|1.012203391 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADQVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>579|beta-lactamase_S80K|1.012179154 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLKRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>580|beta-lactamase_D99E|1.012179154 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNELVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>581|beta-lactamase_L73I|1.012054447 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVILCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>582|beta-lactamase_F58W|1.012054447 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESWRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>583|beta-lactamase_A225H|1.012054447 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPHGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>584|beta-lactamase_Q265E|1.012054447 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSEATMDERNRQIAEIGASLIKHW +>585|beta-lactamase_F22C|1.012054447 +MSIQHFRVALIPFFAAFCLPVCAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>586|beta-lactamase_K144R|1.012032555 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPRELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>587|beta-lactamase_I3P|1.011708669 +MSPQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>588|beta-lactamase_R189K|1.011647195 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLKKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>589|beta-lactamase_A225E|1.011598622 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPEGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>590|beta-lactamase_A276S|1.011559138 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQISEIGASLIKHW +>591|beta-lactamase_A222S|1.011516918 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSSLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>592|beta-lactamase_H156N|1.011455639 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDNVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>593|beta-lactamase_K53I|1.0113966090000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGIILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>594|beta-lactamase_L135I|1.011375792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANILLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>595|beta-lactamase_T186G|1.011321452 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAGTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>596|beta-lactamase_E175Q|1.011316761 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDQRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>597|beta-lactamase_E166L|1.011275518 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPLLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>598|beta-lactamase_E175A|1.011275518 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDARDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>599|beta-lactamase_Q204C|1.011181792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQCLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>600|beta-lactamase_V157Q|1.011181792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHQTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>601|beta-lactamase_A148L|1.011181792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTLFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>602|beta-lactamase_A280D|1.011181792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGDSLIKHW +>603|beta-lactamase_G39A|1.011181792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLAARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>604|beta-lactamase_T193H|1.011181792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLHGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>605|beta-lactamase_I54L|1.011181792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKLLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>606|beta-lactamase_D113T|1.011181792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTTGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>607|beta-lactamase_Q37F|1.011181792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDFLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>608|beta-lactamase_L199Q|1.011181792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTQASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>609|beta-lactamase_H94M|1.011181792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIMYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>610|beta-lactamase_K109G|1.011181792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEGHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>611|beta-lactamase_K284Y|1.011181792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIYHW +>612|beta-lactamase_N173R|1.011181792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPRDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>613|beta-lactamase_P20K|1.011181792 +MSIQHFRVALIPFFAAFCLKVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>614|beta-lactamase_H151R|1.011054935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLRNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>615|beta-lactamase_Y95F|1.011011542 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHFSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>616|beta-lactamase_K190R|1.01099571 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRRLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>617|beta-lactamase_A200G|1.010918403 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLGSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>618|beta-lactamase_H94T|1.010905405 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRITYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>619|beta-lactamase_P60E|1.010758708 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFREEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>620|beta-lactamase_D269A|1.010716487 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMAERNRQIAEIGASLIKHW +>621|beta-lactamase_D33I|1.010644849 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKIAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>622|beta-lactamase_D113E|1.010644849 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTEGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>623|beta-lactamase_E175D|1.010520143 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDDRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>624|beta-lactamase_E61Y|1.010509001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPYERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>625|beta-lactamase_A185G|1.010447039 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMGTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>626|beta-lactamase_T267D|1.010388595 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQADMDERNRQIAEIGASLIKHW +>627|beta-lactamase_E175H|1.010344126 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDHRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>628|beta-lactamase_A225D|1.010309236 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPDGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>629|beta-lactamase_D207G|1.010281089 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIGWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>630|beta-lactamase_H94V|1.010251085 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIVYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>631|beta-lactamase_Q203K|1.010207789 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRKQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>632|beta-lactamase_L10T|1.010166448 +MSIQHFRVATIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>633|beta-lactamase_H285N|1.010121491 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKNW +>634|beta-lactamase_A148G|1.010061875 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTGFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>635|beta-lactamase_A211E|1.010018384 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEEDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>636|beta-lactamase_E169S|1.010018384 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNSAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>637|beta-lactamase_V29D|1.010018384 +MSIQHFRVALIPFFAAFCLPVFAHPETLDKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>638|beta-lactamase_V29E|1.010018384 +MSIQHFRVALIPFFAAFCLPVFAHPETLEKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>639|beta-lactamase_T112P|1.010018384 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLPDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>640|beta-lactamase_A16C|1.010018384 +MSIQHFRVALIPFFACFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>641|beta-lactamase_K252V|1.009971276 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGVPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>642|beta-lactamase_Q88A|1.009906773 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEALGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>643|beta-lactamase_L160V|1.00986465 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRVDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>644|beta-lactamase_L191M|1.009819693 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKMLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>645|beta-lactamase_L111V|1.009819693 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHVTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>646|beta-lactamase_R81K|1.009819693 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSKVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>647|beta-lactamase_N173C|1.009819693 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPCDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>648|beta-lactamase_Q97P|1.009650518 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSPNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>649|beta-lactamase_N50T|1.009644752 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLTSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>650|beta-lactamase_E166M|1.009630483 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPMLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>651|beta-lactamase_I206A|1.009539298 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLADWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>652|beta-lactamase_V8H|1.009539298 +MSIQHFRHALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>653|beta-lactamase_R238F|1.009492875 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEFGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>654|beta-lactamase_G76A|1.009475381 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCAAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>655|beta-lactamase_A280S|1.009475381 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGSSLIKHW +>656|beta-lactamase_I206V|1.009460526 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLVDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>657|beta-lactamase_Q97K|1.009460526 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSKNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>658|beta-lactamase_D250S|1.009451828 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPSGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>659|beta-lactamase_E175I|1.009303958 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDIRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>660|beta-lactamase_I171C|1.009277961 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEACPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>661|beta-lactamase_N173A|1.009277961 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPADERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>662|beta-lactamase_A170V|1.009219029 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEVIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>663|beta-lactamase_Q265T|1.009215412 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSTATMDERNRQIAEIGASLIKHW +>664|beta-lactamase_A148Q|1.009187265 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTQFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>665|beta-lactamase_E169W|1.00911338 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNWAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>666|beta-lactamase_N98I|1.009052101 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQIDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>667|beta-lactamase_Q37E|1.009000303 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDELGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>668|beta-lactamase_T138T|1.008987895 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>669|beta-lactamase_N98Y|1.008917719 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQYDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>670|beta-lactamase_A84T|1.008884294 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDTGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>671|beta-lactamase_H24G|1.008884294 +MSIQHFRVALIPFFAAFCLPVFAGPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>672|beta-lactamase_M153S|1.008765354 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNSGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>673|beta-lactamase_G251K|1.008660975 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDKKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>674|beta-lactamase_Q97L|1.0085909990000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSLNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>675|beta-lactamase_I171R|1.008564025 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEARPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>676|beta-lactamase_D36E|1.008522488 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEEQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>677|beta-lactamase_A222T|1.008460037 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSTLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>678|beta-lactamase_F70M|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTMKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>679|beta-lactamase_A222N|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSNLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>680|beta-lactamase_V157N|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHNTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>681|beta-lactamase_A211H|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEHDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>682|beta-lactamase_A211N|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMENDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>683|beta-lactamase_A280V|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGVSLIKHW +>684|beta-lactamase_D33N|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKNAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>685|beta-lactamase_T193E|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLEGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>686|beta-lactamase_L196C|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGECLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>687|beta-lactamase_E26I|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPITLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>688|beta-lactamase_K32A|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVADAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>689|beta-lactamase_K32R|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVRDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>690|beta-lactamase_Q37M|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDMLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>691|beta-lactamase_T112H|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLHDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>692|beta-lactamase_H94Y|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIYYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>693|beta-lactamase_K213M|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADMVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>694|beta-lactamase_R273E|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNEQIAEIGASLIKHW +>695|beta-lactamase_N152A|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHAMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>696|beta-lactamase_K284R|1.008389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIRHW +>697|beta-lactamase_A9M|1.008389474 +MSIQHFRVMLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>698|beta-lactamase_C18T|1.008389474 +MSIQHFRVALIPFFAAFTLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>699|beta-lactamase_L19G|1.008389474 +MSIQHFRVALIPFFAAFCGPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>700|beta-lactamase_Q4H|1.008389474 +MSIHHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>701|beta-lactamase_R7T|1.008389474 +MSIQHFTVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>702|beta-lactamase_S2L|1.008389474 +MLIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>703|beta-lactamase_Q86A|1.008173485 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGAEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>704|beta-lactamase_H24S|1.008138888 +MSIQHFRVALIPFFAAFCLPVFASPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>705|beta-lactamase_A266C|1.008020631 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQCTMDERNRQIAEIGASLIKHW +>706|beta-lactamase_A148T|1.007989161 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTTFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>707|beta-lactamase_K109A|1.007982222 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEAHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>708|beta-lactamase_K284S|1.007825655 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLISHW +>709|beta-lactamase_E169A|1.007765647 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNAAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>710|beta-lactamase_I171Y|1.007748642 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAYPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>711|beta-lactamase_M180Y|1.00769137 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTYPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>712|beta-lactamase_S122Q|1.00769137 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCQAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>713|beta-lactamase_N152G|1.00769137 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHGMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>714|beta-lactamase_A40G|1.007622957 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGGRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>715|beta-lactamase_T138S|1.007583473 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLSTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>716|beta-lactamase_Q203T|1.007539591 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRTQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>717|beta-lactamase_M180H|1.007435995 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTHPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>718|beta-lactamase_I171S|1.007412148 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEASPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>719|beta-lactamase_T186H|1.0073956309999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAHTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>720|beta-lactamase_M153L|1.007303567 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNLGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>721|beta-lactamase_P60K|1.007303567 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRKEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>722|beta-lactamase_Q204T|1.007303567 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQTLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>723|beta-lactamase_A148K|1.007303567 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTKFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>724|beta-lactamase_S122Y|1.007303567 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCYAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>725|beta-lactamase_K190S|1.007303567 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRSLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>726|beta-lactamase_K109Q|1.007303567 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEQHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>727|beta-lactamase_E195G|1.007303567 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGGLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>728|beta-lactamase_Q97H|1.00723965 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSHNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>729|beta-lactamase_M180V|1.007173681 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTVPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>730|beta-lactamase_T186Q|1.007167817 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAQTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>731|beta-lactamase_S80H|1.00712843 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLHRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>732|beta-lactamase_L196W|1.00712843 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEWLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>733|beta-lactamase_H94F|1.00712843 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIFYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>734|beta-lactamase_S281I|1.007017797 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAILIKHW +>735|beta-lactamase_A15I|1.007017797 +MSIQHFRVALIPFFIAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>736|beta-lactamase_A225V|1.006950948 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPVGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>737|beta-lactamase_A225G|1.006917328 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPGGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>738|beta-lactamase_Q204N|1.006885858 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQNLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>739|beta-lactamase_S254M|1.006885858 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPMRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>740|beta-lactamase_G39N|1.006885858 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLNARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>741|beta-lactamase_E145H|1.006885858 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKHLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>742|beta-lactamase_V8I|1.006885858 +MSIQHFRIALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>743|beta-lactamase_A84G|1.006782946 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDGGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>744|beta-lactamase_T186D|1.006760565 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMADTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>745|beta-lactamase_I93V|1.00675343 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRVHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>746|beta-lactamase_S254H|1.006725968 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPHRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>747|beta-lactamase_S233T|1.006700264 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKTGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>748|beta-lactamase_S221S|1.00661055 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>749|beta-lactamase_E175L|1.00655904 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDLRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>750|beta-lactamase_I45F|1.0065278640000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYFELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>751|beta-lactamase_A276H|1.0065278640000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIHEIGASLIKHW +>752|beta-lactamase_F13A|1.0065278640000002 +MSIQHFRVALIPAFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>753|beta-lactamase_V8L|1.0065278640000002 +MSIQHFRLALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>754|beta-lactamase_L196V|1.006462383 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEVLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>755|beta-lactamase_M67C|1.006410096 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMCSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>756|beta-lactamase_E169G|1.006375889 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNGAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>757|beta-lactamase_H151Y|1.006367387 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLYNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>758|beta-lactamase_H94K|1.006367387 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIKYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>759|beta-lactamase_P172A|1.006328978 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIANDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>760|beta-lactamase_M180A|1.006302004 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTAPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>761|beta-lactamase_K109E|1.006244146 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEEHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>762|beta-lactamase_T193I|1.00621766 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLIGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>763|beta-lactamase_L55I|1.006176613 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIIESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>764|beta-lactamase_R118T|1.006123251 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVTELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>765|beta-lactamase_L282M|1.005946159 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASMIKHW +>766|beta-lactamase_A77C|1.005946159 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGCVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>767|beta-lactamase_A77Q|1.005946159 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGQVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>768|beta-lactamase_G39R|1.005946159 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLRARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>769|beta-lactamase_R273G|1.005946159 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNGQIAEIGASLIKHW +>770|beta-lactamase_Q97S|1.005946159 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSSNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>771|beta-lactamase_A16H|1.005946159 +MSIQHFRVALIPFFAHFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>772|beta-lactamase_H5K|1.005946159 +MSIQKFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>773|beta-lactamase_I11C|1.005946159 +MSIQHFRVALCPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>774|beta-lactamase_Q97T|1.00566205 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSTNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>775|beta-lactamase_D250A|1.005655307 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPAGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>776|beta-lactamase_L167I|1.005597156 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEINEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>777|beta-lactamase_T112N|1.005597156 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLNDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>778|beta-lactamase_A225S|1.005568325 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPSGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>779|beta-lactamase_N173K|1.005534412 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPKDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>780|beta-lactamase_A84Q|1.005493657 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDQGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>781|beta-lactamase_T112V|1.005493657 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLVDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>782|beta-lactamase_F14I|1.005457496 +MSIQHFRVALIPFIAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>783|beta-lactamase_L223C|1.005427883 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSACPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>784|beta-lactamase_A280R|1.005414982 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGRSLIKHW +>785|beta-lactamase_E102A|1.005414982 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVAYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>786|beta-lactamase_A266S|1.005372273 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQSTMDERNRQIAEIGASLIKHW +>787|beta-lactamase_Q274A|1.005303176 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRAIAEIGASLIKHW +>788|beta-lactamase_E166N|1.005303176 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPNLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>789|beta-lactamase_K252M|1.005303176 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGMPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>790|beta-lactamase_Q265F|1.005303176 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSFATMDERNRQIAEIGASLIKHW +>791|beta-lactamase_H24D|1.005303176 +MSIQHFRVALIPFFAAFCLPVFADPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>792|beta-lactamase_E277T|1.0052275309999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIATIGASLIKHW +>793|beta-lactamase_P25H|1.0052275309999998 +MSIQHFRVALIPFFAAFCLPVFAHHETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>794|beta-lactamase_T267S|1.00516938 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQASMDERNRQIAEIGASLIKHW +>795|beta-lactamase_E237D|1.005164591 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGDRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>796|beta-lactamase_A222I|1.005131753 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSILPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>797|beta-lactamase_A148C|1.005131753 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTCFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>798|beta-lactamase_M153A|1.005052297 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNAGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>799|beta-lactamase_R118C|1.00500646 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVCELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>800|beta-lactamase_Q37R|1.00498535 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDRLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>801|beta-lactamase_F228Y|1.004835526 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWYIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>802|beta-lactamase_L111I|1.004835526 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHITDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>803|beta-lactamase_G90T|1.004835526 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLTRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>804|beta-lactamase_E166I|1.004835526 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPILNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>805|beta-lactamase_T186S|1.004766918 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMASTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>806|beta-lactamase_A200C|1.004756949 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLCSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>807|beta-lactamase_S221K|1.004724502 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRKALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>808|beta-lactamase_H94R|1.004693129 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIRYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>809|beta-lactamase_K144T|1.004626964 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPTELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>810|beta-lactamase_T139I|1.00448017 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTIIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>811|beta-lactamase_L10A|1.00448017 +MSIQHFRVAAIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>812|beta-lactamase_L146M|1.004379896 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEMTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>813|beta-lactamase_L223T|1.004379896 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSATPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>814|beta-lactamase_N50Y|1.004379896 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLYSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>815|beta-lactamase_N152K|1.004332692 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHKMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>816|beta-lactamase_R189A|1.00429526 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLAKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>817|beta-lactamase_A222V|1.004238477 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>818|beta-lactamase_A266M|1.004200948 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQMTMDERNRQIAEIGASLIKHW +>819|beta-lactamase_K284L|1.004200948 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLILHW +>820|beta-lactamase_S2T|1.004200948 +MTIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>821|beta-lactamase_L191L|1.004180693 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>822|beta-lactamase_E61R|1.004131851 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPRERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>823|beta-lactamase_S254N|1.004045846 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPNRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>824|beta-lactamase_T267G|1.004045846 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAGMDERNRQIAEIGASLIKHW +>825|beta-lactamase_R189S|1.004020925 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLSKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>826|beta-lactamase_A211C|1.003975772 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMECDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>827|beta-lactamase_Q203V|1.003975772 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRVQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>828|beta-lactamase_A200R|1.003953391 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLRSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>829|beta-lactamase_K213R|1.003950655 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADRVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>830|beta-lactamase_A266K|1.003935799 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQKTMDERNRQIAEIGASLIKHW +>831|beta-lactamase_G90A|1.003929838 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLARRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>832|beta-lactamase_D250K|1.003833473 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPKGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>833|beta-lactamase_I206F|1.003790276 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLFDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>834|beta-lactamase_Q37S|1.003790276 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDSLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>835|beta-lactamase_H94W|1.003790276 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIWYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>836|beta-lactamase_A222E|1.003743168 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSELPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>837|beta-lactamase_A124A|1.003716137 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>838|beta-lactamase_E145R|1.003655502 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKRLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>839|beta-lactamase_S281Q|1.003634881 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAQLIKHW +>840|beta-lactamase_L111T|1.003634881 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHTTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>841|beta-lactamase_N173S|1.003338165 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPSDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>842|beta-lactamase_E270K|1.003290373 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDKRNRQIAEIGASLIKHW +>843|beta-lactamase_T138G|1.003290373 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLGTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>844|beta-lactamase_E195D|1.003290373 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGDLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>845|beta-lactamase_A246I|1.003245612 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAILGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>846|beta-lactamase_S122I|1.003203685 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCIAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>847|beta-lactamase_Q97I|1.003203685 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSINDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>848|beta-lactamase_S240A|1.003190197 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGARGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>849|beta-lactamase_D269G|1.003190197 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMGERNRQIAEIGASLIKHW +>850|beta-lactamase_H94Q|1.003187559 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIQYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>851|beta-lactamase_L160I|1.003126964 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRIDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>852|beta-lactamase_T186N|1.003126964 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMANTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>853|beta-lactamase_T186Y|1.003126964 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAYTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>854|beta-lactamase_R189H|1.003126964 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLHKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>855|beta-lactamase_E237R|1.003126964 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGRRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>856|beta-lactamase_T112G|1.003126964 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLGDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>857|beta-lactamase_K284A|1.003126964 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIAHW +>858|beta-lactamase_P60S|1.00309872 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRSEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>859|beta-lactamase_I45C|1.002997371 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYCELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>860|beta-lactamase_H156C|1.002997371 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDCVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>861|beta-lactamase_Q97A|1.002969029 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSANDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>862|beta-lactamase_A148Y|1.00280474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTYFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>863|beta-lactamase_K190G|1.00280474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRGLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>864|beta-lactamase_P12C|1.00280474 +MSIQHFRVALICFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>865|beta-lactamase_D250R|1.002772684 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPRGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>866|beta-lactamase_S96T|1.002766527 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYTQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>867|beta-lactamase_L188F|1.002731245 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTFRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>868|beta-lactamase_Q86L|1.002731245 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGLEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>869|beta-lactamase_K252R|1.002684724 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGRPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>870|beta-lactamase_Q88S|1.002655796 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQESLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>871|beta-lactamase_V42L|1.002649638 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARLGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>872|beta-lactamase_A170G|1.002640452 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEGIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>873|beta-lactamase_F228F|1.002595167 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>874|beta-lactamase_Q86T|1.002567152 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGTEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>875|beta-lactamase_P12F|1.002567152 +MSIQHFRVALIFFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>876|beta-lactamase_L196M|1.002488673 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEMLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>877|beta-lactamase_A225I|1.002488673 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPIGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>878|beta-lactamase_A211S|1.002426124 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMESDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>879|beta-lactamase_H156Q|1.002426124 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDQVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>880|beta-lactamase_Q88E|1.002375205 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEELGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>881|beta-lactamase_Q88N|1.002323309 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQENLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>882|beta-lactamase_L135L|1.002287225 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>883|beta-lactamase_P12H|1.002228118 +MSIQHFRVALIHFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>884|beta-lactamase_T198S|1.002147684 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLSLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>885|beta-lactamase_E175Y|1.002128528 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDYRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>886|beta-lactamase_V31C|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKCKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>887|beta-lactamase_A77N|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGNVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>888|beta-lactamase_E46T|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYITLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>889|beta-lactamase_Q274E|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNREIAEIGASLIKHW +>890|beta-lactamase_S281H|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAHLIKHW +>891|beta-lactamase_L49V|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDVNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>892|beta-lactamase_I206W|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLWDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>893|beta-lactamase_T139Q|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTQIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>894|beta-lactamase_G216Q|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAQPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>895|beta-lactamase_A280N|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGNSLIKHW +>896|beta-lactamase_S254E|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPERIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>897|beta-lactamase_S122K|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCKAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>898|beta-lactamase_L111M|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHMTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>899|beta-lactamase_D33G|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKGAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>900|beta-lactamase_D207Q|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIQWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>901|beta-lactamase_E119D|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRDLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>902|beta-lactamase_L196F|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEFLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>903|beta-lactamase_Q203N|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRNQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>904|beta-lactamase_D36S|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAESQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>905|beta-lactamase_E26A|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPATLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>906|beta-lactamase_Q86D|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGDEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>907|beta-lactamase_T112A|1.001873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLADGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>908|beta-lactamase_S2Q|1.001873935 +MQIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>909|beta-lactamase_S221T|1.001833669 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRTALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>910|beta-lactamase_A182G|1.00169097 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPGAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>911|beta-lactamase_S57S|1.001655125 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>912|beta-lactamase_E237L|1.001629007 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGLRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>913|beta-lactamase_K53S|1.001503714 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGSILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>914|beta-lactamase_D269S|1.001495113 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMSERNRQIAEIGASLIKHW +>915|beta-lactamase_S96G|1.001339914 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYGQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>916|beta-lactamase_A225C|1.001326427 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPCGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>917|beta-lactamase_N173F|1.0013122559999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPFDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>918|beta-lactamase_A170S|1.001281665 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNESIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>919|beta-lactamase_M153I|1.001209148 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNIGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>920|beta-lactamase_L167V|1.001180805 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEVNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>921|beta-lactamase_E61T|1.00115002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPTERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>922|beta-lactamase_E175W|1.001016615 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDWRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>923|beta-lactamase_A148I|1.000823104 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTIFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>924|beta-lactamase_A280H|1.000823104 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGHSLIKHW +>925|beta-lactamase_E195Q|1.000823104 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGQLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>926|beta-lactamase_I206T|1.000769644 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLTDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>927|beta-lactamase_E270M|1.000710516 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDMRNRQIAEIGASLIKHW +>928|beta-lactamase_D269Y|1.000710516 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMYERNRQIAEIGASLIKHW +>929|beta-lactamase_A34S|1.000644644 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDSEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>930|beta-lactamase_R118Q|1.000644644 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVQELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>931|beta-lactamase_T138M|1.000570856 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLMTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>932|beta-lactamase_H94N|1.000570856 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRINYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>933|beta-lactamase_V8Q|1.000570856 +MSIQHFRQALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>934|beta-lactamase_E166Q|1.0005388000000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPQLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>935|beta-lactamase_Q88D|1.00053059 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEDLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>936|beta-lactamase_H151Q|1.000516517 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLQNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>937|beta-lactamase_A182S|1.000441947 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPSAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>938|beta-lactamase_A170C|1.000393178 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNECIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>939|beta-lactamase_E169T|1.000393178 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNTAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>940|beta-lactamase_M115L|1.000322615 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGLTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>941|beta-lactamase_K144I|1.000322615 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPIELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>942|beta-lactamase_D250G|1.000295348 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPGGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>943|beta-lactamase_M127W|1.000284793 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITWSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>944|beta-lactamase_K252A|1.000284793 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGAPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>945|beta-lactamase_L219L|1.00023522 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>946|beta-lactamase_V42I|1.000224492 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARIGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>947|beta-lactamase_P249K|1.000159304 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGKDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>948|beta-lactamase_E169L|1.000159304 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNLAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>949|beta-lactamase_K213L|1.00011982 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADLVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>950|beta-lactamase_N50S|0.999979867 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLSSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>951|beta-lactamase_M67G|0.999837862 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMGSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>952|beta-lactamase_T261V|0.999837862 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYVTGSQATMDERNRQIAEIGASLIKHW +>953|beta-lactamase_G85G|0.999638972 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>954|beta-lactamase_I244V|0.999612295 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIVAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>955|beta-lactamase_Q86H|0.99957975 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGHEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>956|beta-lactamase_D207T|0.999547009 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLITWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>957|beta-lactamase_D36Y|0.999478597 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEYQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>958|beta-lactamase_H24R|0.999478597 +MSIQHFRVALIPFFAAFCLPVFARPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>959|beta-lactamase_I259V|0.999415266 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVVYTTGSQATMDERNRQIAEIGASLIKHW +>960|beta-lactamase_V72P|0.999367963 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKPLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>961|beta-lactamase_A148H|0.999367963 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTHFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>962|beta-lactamase_K190H|0.999367963 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRHLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>963|beta-lactamase_A225Y|0.999367963 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPYGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>964|beta-lactamase_E175N|0.999367963 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDNRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>965|beta-lactamase_K109L|0.999367963 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTELHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>966|beta-lactamase_Q4S|0.999367963 +MSISHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>967|beta-lactamase_P12A|0.999314308 +MSIQHFRVALIAFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>968|beta-lactamase_A266G|0.999227033 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQGTMDERNRQIAEIGASLIKHW +>969|beta-lactamase_A148V|0.999221071 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTVFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>970|beta-lactamase_D36N|0.999214523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAENQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>971|beta-lactamase_H151N|0.999214523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLNNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>972|beta-lactamase_I171F|0.999159206 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAFPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>973|beta-lactamase_A266R|0.999113174 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQRTMDERNRQIAEIGASLIKHW +>974|beta-lactamase_Q265I|0.999041145 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSIATMDERNRQIAEIGASLIKHW +>975|beta-lactamase_W163M|0.998965207 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRMEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>976|beta-lactamase_I171D|0.998912334 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEADPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>977|beta-lactamase_Q203G|0.998912334 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRGQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>978|beta-lactamase_H151G|0.998912334 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLGNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>979|beta-lactamase_Q265R|0.998854574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSRATMDERNRQIAEIGASLIKHW +>980|beta-lactamase_F22L|0.998784695 +MSIQHFRVALIPFFAAFCLPVLAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>981|beta-lactamase_R238Y|0.998776388 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEYGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>982|beta-lactamase_S57M|0.998771306 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEMFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>983|beta-lactamase_S96E|0.998771306 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYEQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>984|beta-lactamase_A211G|0.998733972 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEGDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>985|beta-lactamase_P172D|0.998721267 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIDNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>986|beta-lactamase_L223V|0.998711102 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAVPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>987|beta-lactamase_C75V|0.998616204 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLVGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>988|beta-lactamase_A182W|0.998616204 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPWAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>989|beta-lactamase_G90M|0.998616204 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLMRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>990|beta-lactamase_G90N|0.998616204 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLNRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>991|beta-lactamase_R159K|0.998616204 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTKLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>992|beta-lactamase_T267E|0.998616204 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAEMDERNRQIAEIGASLIKHW +>993|beta-lactamase_H94L|0.998616204 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRILYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>994|beta-lactamase_Q97D|0.998616204 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSDNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>995|beta-lactamase_Q97G|0.998539289 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSGNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>996|beta-lactamase_K252S|0.998439601 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGSPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>997|beta-lactamase_A276R|0.998428264 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIREIGASLIKHW +>998|beta-lactamase_T198K|0.998408229 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLKLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>999|beta-lactamase_A246V|0.998393667 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAVLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1000|beta-lactamase_S221R|0.99827844 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRRALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1001|beta-lactamase_Q37H|0.998254203 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDHLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1002|beta-lactamase_F13L|0.998188135 +MSIQHFRVALIPLFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1003|beta-lactamase_A182C|0.998172009 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPCAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1004|beta-lactamase_E61N|0.998115031 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPNERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1005|beta-lactamase_P172E|0.998092651 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIENDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1006|beta-lactamase_K53H|0.998041341 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGHILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1007|beta-lactamase_Q4R|0.997956998 +MSIRHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1008|beta-lactamase_K53R|0.997948984 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGRILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1009|beta-lactamase_L150I|0.997925137 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFIHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1010|beta-lactamase_S57E|0.997901095 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEEFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1011|beta-lactamase_M127E|0.997801798 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITESDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1012|beta-lactamase_K53M|0.997801798 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGMILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1013|beta-lactamase_R202S|0.997750195 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASSQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1014|beta-lactamase_A200P|0.997715109 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLPSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1015|beta-lactamase_K53L|0.997670446 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGLILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1016|beta-lactamase_R118F|0.997587471 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVFELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1017|beta-lactamase_H156R|0.997587471 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDRVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1018|beta-lactamase_H151L|0.997507916 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLLNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1019|beta-lactamase_Q88F|0.997456704 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEFLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1020|beta-lactamase_Q88Y|0.997411259 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEYLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1021|beta-lactamase_E169K|0.997380473 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNKAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1022|beta-lactamase_A34V|0.99736855 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDVEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1023|beta-lactamase_S281R|0.997219996 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGARLIKHW +>1024|beta-lactamase_I206C|0.997219996 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLCDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1025|beta-lactamase_M180N|0.997219996 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTNPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1026|beta-lactamase_Q203S|0.997219996 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRSQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1027|beta-lactamase_D269H|0.997219996 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMHERNRQIAEIGASLIKHW +>1028|beta-lactamase_R273A|0.997219996 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNAQIAEIGASLIKHW +>1029|beta-lactamase_K284Q|0.997219996 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIQHW +>1030|beta-lactamase_K144F|0.997219996 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPFELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1031|beta-lactamase_P20N|0.997219996 +MSIQHFRVALIPFFAAFCLNVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1032|beta-lactamase_D269V|0.997160575 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMVERNRQIAEIGASLIKHW +>1033|beta-lactamase_S96L|0.99713536 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYLQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1034|beta-lactamase_P25Q|0.997031372 +MSIQHFRVALIPFFAAFCLPVFAHQETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1035|beta-lactamase_V117I|0.996987295 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTIRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1036|beta-lactamase_S254G|0.996931196 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPGRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1037|beta-lactamase_F6K|0.996916536 +MSIQHKRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1038|beta-lactamase_S254D|0.996900313 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPDRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1039|beta-lactamase_P12Y|0.996862002 +MSIQHFRVALIYFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1040|beta-lactamase_S122F|0.996661552 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCFAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1041|beta-lactamase_E237K|0.996585418 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1042|beta-lactamase_K144L|0.996570661 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPLELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1043|beta-lactamase_D33D|0.996526055 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1044|beta-lactamase_G194D|0.996513096 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTDELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1045|beta-lactamase_P60M|0.99644439 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRMEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1046|beta-lactamase_D33L|0.99644439 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKLAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1047|beta-lactamase_P217Q|0.99644439 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGQLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1048|beta-lactamase_S221Q|0.99644439 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRQALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1049|beta-lactamase_L282V|0.996409304 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASVIKHW +>1050|beta-lactamase_D99Q|0.996360829 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNQLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1051|beta-lactamase_E56G|0.996343335 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILGSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1052|beta-lactamase_E61K|0.996189308 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPKERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1053|beta-lactamase_K109T|0.996172889 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTETHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1054|beta-lactamase_R238K|0.996150899 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEKGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1055|beta-lactamase_A84L|0.996125 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDLGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1056|beta-lactamase_M67N|0.996072518 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMNSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1057|beta-lactamase_P253A|0.996056587 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKASRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1058|beta-lactamase_S221A|0.996050919 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRAALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1059|beta-lactamase_A84V|0.995983581 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDVGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1060|beta-lactamase_G39S|0.995950743 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLSARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1061|beta-lactamase_S51E|0.995950743 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNEGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1062|beta-lactamase_R189W|0.995950743 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLWKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1063|beta-lactamase_T267Q|0.995950743 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAQMDERNRQIAEIGASLIKHW +>1064|beta-lactamase_Q37W|0.995950743 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDWLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1065|beta-lactamase_Y95Y|0.995827742 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1066|beta-lactamase_K53V|0.995784695 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGVILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1067|beta-lactamase_R7H|0.995668686 +MSIQHFHVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1068|beta-lactamase_A211L|0.99560907 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMELDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1069|beta-lactamase_R176Q|0.995568608 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEQDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1070|beta-lactamase_T186K|0.995517396 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAKTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1071|beta-lactamase_K53Y|0.995517396 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGYILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1072|beta-lactamase_N50K|0.995474785 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLKSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1073|beta-lactamase_P60H|0.995403049 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRHEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1074|beta-lactamase_E195E|0.99536007 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1075|beta-lactamase_I45M|0.995358483 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYMELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1076|beta-lactamase_K190A|0.995358483 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRALLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1077|beta-lactamase_E145M|0.995358483 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKMLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1078|beta-lactamase_I3L|0.995289093 +MSLQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1079|beta-lactamase_M127T|0.995256646 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITTSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1080|beta-lactamase_L196P|0.995256646 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEPLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1081|beta-lactamase_D269I|0.995256646 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMIERNRQIAEIGASLIKHW +>1082|beta-lactamase_L49I|0.99516683 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDINSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1083|beta-lactamase_E169Q|0.995112588 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNQAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1084|beta-lactamase_E169D|0.995100371 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNDAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1085|beta-lactamase_P20R|0.995015539 +MSIQHFRVALIPFFAAFCLRVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1086|beta-lactamase_Q4Y|0.995015539 +MSIYHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1087|beta-lactamase_T126S|0.994951231 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAISMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1088|beta-lactamase_A200K|0.994791927 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLKSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1089|beta-lactamase_W163V|0.994791927 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRVEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1090|beta-lactamase_T198N|0.994747654 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLNLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1091|beta-lactamase_Q86Y|0.99463448 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGYEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1092|beta-lactamase_T267A|0.994493061 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAAMDERNRQIAEIGASLIKHW +>1093|beta-lactamase_G90S|0.994469996 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLSRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1094|beta-lactamase_K144Y|0.994427678 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPYELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1095|beta-lactamase_A183V|0.994125782 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAVMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1096|beta-lactamase_P60Q|0.99407369 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRQEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1097|beta-lactamase_Q88T|0.99407369 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQETLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1098|beta-lactamase_I3Y|0.994055317 +MSYQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1099|beta-lactamase_S80F|0.99402111 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLFRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1100|beta-lactamase_K144Q|0.993957877 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPQELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1101|beta-lactamase_A225R|0.993819781 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPRGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1102|beta-lactamase_T187D|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATDLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1103|beta-lactamase_S264T|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGTQATMDERNRQIAEIGASLIKHW +>1104|beta-lactamase_A182T|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPTAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1105|beta-lactamase_A183Q|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAQMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1106|beta-lactamase_L49Y|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDYNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1107|beta-lactamase_G194Q|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTQELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1108|beta-lactamase_V106M|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPMTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1109|beta-lactamase_V157A|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHATRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1110|beta-lactamase_L28H|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETHVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1111|beta-lactamase_R81N|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSNVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1112|beta-lactamase_H285Y|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKYW +>1113|beta-lactamase_E169F|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNFAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1114|beta-lactamase_E210Q|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMQADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1115|beta-lactamase_E26K|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPKTLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1116|beta-lactamase_E277R|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIARIGASLIKHW +>1117|beta-lactamase_D113N|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTNGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1118|beta-lactamase_Q37T|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDTLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1119|beta-lactamase_L199H|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTHASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1120|beta-lactamase_H156T|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDTVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1121|beta-lactamase_R273T|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNTQIAEIGASLIKHW +>1122|beta-lactamase_R273Y|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNYQIAEIGASLIKHW +>1123|beta-lactamase_E61W|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPWERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1124|beta-lactamase_E195S|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGSLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1125|beta-lactamase_C18W|0.993729574 +MSIQHFRVALIPFFAAFWLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1126|beta-lactamase_I3H|0.993729574 +MSHQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1127|beta-lactamase_P25E|0.993729574 +MSIQHFRVALIPFFAAFCLPVFAHEETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1128|beta-lactamase_P12S|0.993626466 +MSIQHFRVALISFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1129|beta-lactamase_I206S|0.993466869 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLSDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1130|beta-lactamase_A230A|0.993425476 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1131|beta-lactamase_S57Q|0.99339484 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEQFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1132|beta-lactamase_K252C|0.993375489 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGCPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1133|beta-lactamase_D113A|0.993268569 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTAGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1134|beta-lactamase_N173T|0.993268569 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPTDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1135|beta-lactamase_K190Y|0.993186572 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRYLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1136|beta-lactamase_L73V|0.993086591 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVVLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1137|beta-lactamase_L282I|0.993069195 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASIIKHW +>1138|beta-lactamase_A225L|0.993044566 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPLGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1139|beta-lactamase_S96A|0.993039386 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYAQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1140|beta-lactamase_E61L|0.993013976 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPLERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1141|beta-lactamase_S96R|0.993001759 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYRQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1142|beta-lactamase_I45L|0.992989152 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYLELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1143|beta-lactamase_E145C|0.992989152 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKCLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1144|beta-lactamase_D269N|0.992989152 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMNERNRQIAEIGASLIKHW +>1145|beta-lactamase_Q265V|0.992941358 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSVATMDERNRQIAEIGASLIKHW +>1146|beta-lactamase_T261I|0.992887018 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYITGSQATMDERNRQIAEIGASLIKHW +>1147|beta-lactamase_Q204A|0.992887018 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQALIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1148|beta-lactamase_V157E|0.992887018 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHETRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1149|beta-lactamase_P217D|0.992887018 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGDLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1150|beta-lactamase_A84H|0.992887018 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDHGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1151|beta-lactamase_E166K|0.99281108 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPKLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1152|beta-lactamase_G226N|0.992752245 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPANWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1153|beta-lactamase_P12W|0.992752245 +MSIQHFRVALIWFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1154|beta-lactamase_A84E|0.992667218 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDEGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1155|beta-lactamase_E237C|0.992667218 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGCRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1156|beta-lactamase_T131S|0.992566064 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNSAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1157|beta-lactamase_F13T|0.992487194 +MSIQHFRVALIPTFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1158|beta-lactamase_L196G|0.992443605 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEGLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1159|beta-lactamase_R92L|0.992387116 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRLIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1160|beta-lactamase_P12T|0.992313132 +MSIQHFRVALITFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1161|beta-lactamase_K30A|0.992292315 +MSIQHFRVALIPFFAAFCLPVFAHPETLVAVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1162|beta-lactamase_H151V|0.992292315 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLVNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1163|beta-lactamase_S2Y|0.992292315 +MYIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1164|beta-lactamase_L192F|0.992170052 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLFTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1165|beta-lactamase_D250F|0.99214298 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPFGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1166|beta-lactamase_S80Q|0.992131154 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLQRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1167|beta-lactamase_I11W|0.992100662 +MSIQHFRVALWPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1168|beta-lactamase_E145S|0.992069094 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKSLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1169|beta-lactamase_L188I|0.992056095 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTIRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1170|beta-lactamase_D33E|0.992024919 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKEAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1171|beta-lactamase_E26G|0.992024919 +MSIQHFRVALIPFFAAFCLPVFAHPGTLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1172|beta-lactamase_D269L|0.992017686 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMLERNRQIAEIGASLIKHW +>1173|beta-lactamase_E270C|0.991850075 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDCRNRQIAEIGASLIKHW +>1174|beta-lactamase_E175K|0.991850075 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDKRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1175|beta-lactamase_N98G|0.991850075 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQGDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1176|beta-lactamase_S2M|0.991850075 +MMIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1177|beta-lactamase_S240G|0.991774919 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGGRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1178|beta-lactamase_L188V|0.991752734 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTVRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1179|beta-lactamase_R271L|0.991748531 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDELNRQIAEIGASLIKHW +>1180|beta-lactamase_A211K|0.991508402 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEKDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1181|beta-lactamase_G90Y|0.991508402 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLYRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1182|beta-lactamase_A266V|0.99148436 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQVTMDERNRQIAEIGASLIKHW +>1183|beta-lactamase_R118L|0.991402558 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVLELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1184|beta-lactamase_V29C|0.991365028 +MSIQHFRVALIPFFAAFCLPVFAHPETLCKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1185|beta-lactamase_N50H|0.991365028 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLHSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1186|beta-lactamase_E35E|0.991355489 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1187|beta-lactamase_Q86E|0.991315185 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGEEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1188|beta-lactamase_P172T|0.991280294 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAITNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1189|beta-lactamase_E175S|0.991276483 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDSRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1190|beta-lactamase_E56A|0.991242374 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILASFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1191|beta-lactamase_R189F|0.991236412 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLFKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1192|beta-lactamase_N50A|0.991236412 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLASGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1193|beta-lactamase_P60T|0.991223609 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRTEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1194|beta-lactamase_D250M|0.991217745 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPMGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1195|beta-lactamase_I93L|0.991188523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRLHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1196|beta-lactamase_E175R|0.99111669 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDRRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1197|beta-lactamase_Q274K|0.991014755 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRKIAEIGASLIKHW +>1198|beta-lactamase_E56D|0.991014755 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILDSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1199|beta-lactamase_V101D|0.991014755 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLDEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1200|beta-lactamase_S57K|0.991014755 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEKFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1201|beta-lactamase_T138Y|0.991014755 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLYTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1202|beta-lactamase_R92K|0.991014755 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRKIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1203|beta-lactamase_N50F|0.991014755 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLFSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1204|beta-lactamase_N50R|0.991014755 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLRSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1205|beta-lactamase_L150V|0.990941947 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFVHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1206|beta-lactamase_Q86K|0.990892787 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGKEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1207|beta-lactamase_W163Y|0.990830727 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRYEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1208|beta-lactamase_P172L|0.990760066 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAILNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1209|beta-lactamase_L47M|0.990749902 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEMDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1210|beta-lactamase_A183T|0.990724394 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPATMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1211|beta-lactamase_D269Q|0.99071726 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMQERNRQIAEIGASLIKHW +>1212|beta-lactamase_D250C|0.990567631 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPCGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1213|beta-lactamase_H24E|0.990542611 +MSIQHFRVALIPFFAAFCLPVFAEPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1214|beta-lactamase_A200T|0.990471853 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLTSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1215|beta-lactamase_T138D|0.990471853 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLDTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1216|beta-lactamase_G226G|0.990442958 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1217|beta-lactamase_V82V|0.990415269 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1218|beta-lactamase_E270A|0.99034656 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDARNRQIAEIGASLIKHW +>1219|beta-lactamase_E270Q|0.99034656 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDQRNRQIAEIGASLIKHW +>1220|beta-lactamase_S122A|0.990239152 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCAAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1221|beta-lactamase_T138C|0.990239152 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLCTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1222|beta-lactamase_E175C|0.990239152 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDCRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1223|beta-lactamase_E237Y|0.990239152 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGYRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1224|beta-lactamase_E102M|0.990239152 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVMYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1225|beta-lactamase_Q265D|0.990239152 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSDATMDERNRQIAEIGASLIKHW +>1226|beta-lactamase_T139V|0.990124707 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTVIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1227|beta-lactamase_S122V|0.990124707 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCVAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1228|beta-lactamase_D207R|0.990027561 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIRWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1229|beta-lactamase_I275F|0.989970582 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQFAEIGASLIKHW +>1230|beta-lactamase_K252Y|0.989928851 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGYPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1231|beta-lactamase_S80W|0.989871677 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLWRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1232|beta-lactamase_V157I|0.989871677 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHITRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1233|beta-lactamase_S122H|0.989871677 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCHAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1234|beta-lactamase_V29T|0.989871677 +MSIQHFRVALIPFFAAFCLPVFAHPETLTKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1235|beta-lactamase_Q88W|0.989871677 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEWLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1236|beta-lactamase_S122G|0.98982027 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCGAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1237|beta-lactamase_I125L|0.989788702 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAALTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1238|beta-lactamase_H5Y|0.989788702 +MSIQYFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1239|beta-lactamase_W163I|0.989752052 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRIEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1240|beta-lactamase_S57R|0.989734167 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILERFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1241|beta-lactamase_H110K|0.989657349 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKKLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1242|beta-lactamase_D269T|0.989657349 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMTERNRQIAEIGASLIKHW +>1243|beta-lactamase_A9F|0.989517005 +MSIQHFRVFLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1244|beta-lactamase_T267K|0.989480356 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAKMDERNRQIAEIGASLIKHW +>1245|beta-lactamase_E166V|0.989447518 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPVLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1246|beta-lactamase_I45T|0.989417807 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYTELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1247|beta-lactamase_I206K|0.989417807 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLKDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1248|beta-lactamase_E277I|0.989417807 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAIIGASLIKHW +>1249|beta-lactamase_K109N|0.989344116 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTENHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1250|beta-lactamase_K53E|0.989287138 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGEILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1251|beta-lactamase_A246C|0.989174257 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIACLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1252|beta-lactamase_E270V|0.989136923 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDVRNRQIAEIGASLIKHW +>1253|beta-lactamase_A148A|0.989126446 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1254|beta-lactamase_P172V|0.989090403 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIVNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1255|beta-lactamase_E46Q|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIQLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1256|beta-lactamase_A276Q|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIQEIGASLIKHW +>1257|beta-lactamase_Q274H|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRHIAEIGASLIKHW +>1258|beta-lactamase_Q274Y|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRYIAEIGASLIKHW +>1259|beta-lactamase_I206Q|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLQDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1260|beta-lactamase_I206R|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLRDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1261|beta-lactamase_K30M|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVMVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1262|beta-lactamase_S51N|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNNGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1263|beta-lactamase_D99M|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNMLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1264|beta-lactamase_D207K|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIKWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1265|beta-lactamase_E270S|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDSRNRQIAEIGASLIKHW +>1266|beta-lactamase_E210C|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMCADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1267|beta-lactamase_I54F|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKFLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1268|beta-lactamase_E108I|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTIKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1269|beta-lactamase_Q37I|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDILGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1270|beta-lactamase_L199A|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTAASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1271|beta-lactamase_K213H|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADHVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1272|beta-lactamase_K284N|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLINHW +>1273|beta-lactamase_E195T|0.988842944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGTLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1274|beta-lactamase_F17Y|0.988842944 +MSIQHFRVALIPFFAAYCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1275|beta-lactamase_M180R|0.988787236 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTRPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1276|beta-lactamase_A84S|0.98866683 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDSGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1277|beta-lactamase_S122R|0.988639367 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCRAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1278|beta-lactamase_M180I|0.988493941 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTIPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1279|beta-lactamase_R118D|0.988459636 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVDELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1280|beta-lactamase_Q203A|0.988439894 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRAQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1281|beta-lactamase_S57H|0.988418002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEHFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1282|beta-lactamase_R238Q|0.988309226 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEQGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1283|beta-lactamase_G194E|0.988299941 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTEELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1284|beta-lactamase_V157R|0.988299941 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHRTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1285|beta-lactamase_V8R|0.988244625 +MSIQHFRRALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1286|beta-lactamase_G251A|0.988224883 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDAKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1287|beta-lactamase_L160M|0.988212373 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRMDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1288|beta-lactamase_D113Q|0.988091185 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTQGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1289|beta-lactamase_S51S|0.988072525 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1290|beta-lactamase_S96Q|0.987912138 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYQQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1291|beta-lactamase_A84R|0.987912138 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDRGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1292|beta-lactamase_H5Q|0.987853206 +MSIQQFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1293|beta-lactamase_L111L|0.987852188 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1294|beta-lactamase_E145V|0.987844214 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKVLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1295|beta-lactamase_I283V|0.987770231 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLVKHW +>1296|beta-lactamase_A266E|0.98769312 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQETMDERNRQIAEIGASLIKHW +>1297|beta-lactamase_G226T|0.987621286 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPATWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1298|beta-lactamase_K190Q|0.987621286 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRQLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1299|beta-lactamase_F22S|0.987621286 +MSIQHFRVALIPFFAAFCLPVSAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1300|beta-lactamase_P20E|0.987621286 +MSIQHFRVALIPFFAAFCLEVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1301|beta-lactamase_M268L|0.987479281 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATLDERNRQIAEIGASLIKHW +>1302|beta-lactamase_Q4K|0.987395035 +MSIKHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1303|beta-lactamase_P60R|0.98737412 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRREERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1304|beta-lactamase_D250L|0.987332877 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPLGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1305|beta-lactamase_L28M|0.987299844 +MSIQHFRVALIPFFAAFCLPVFAHPETMVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1306|beta-lactamase_A170Y|0.987247263 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEYIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1307|beta-lactamase_A280G|0.987247263 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGGSLIKHW +>1308|beta-lactamase_A230G|0.987228987 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIGDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1309|beta-lactamase_E61V|0.987209636 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPVERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1310|beta-lactamase_Q88K|0.987197909 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEKLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1311|beta-lactamase_R189C|0.987191165 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLCKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1312|beta-lactamase_L10M|0.98706597 +MSIQHFRVAMIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1313|beta-lactamase_M127V|0.986958952 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITVSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1314|beta-lactamase_I11V|0.986932369 +MSIQHFRVALVPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1315|beta-lactamase_Q88R|0.98689269 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQERLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1316|beta-lactamase_D207L|0.986838155 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLILWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1317|beta-lactamase_A266Q|0.986800723 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQQTMDERNRQIAEIGASLIKHW +>1318|beta-lactamase_P60I|0.986748632 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRIEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1319|beta-lactamase_S80N|0.986726446 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLNRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1320|beta-lactamase_K190V|0.986700841 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRVLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1321|beta-lactamase_S281C|0.98667113 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGACLIKHW +>1322|beta-lactamase_S96W|0.98667113 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYWQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1323|beta-lactamase_G90H|0.98667113 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLHRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1324|beta-lactamase_D113K|0.98667113 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTKGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1325|beta-lactamase_K53Q|0.986616106 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGQILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1326|beta-lactamase_T187S|0.986590696 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATSLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1327|beta-lactamase_E166G|0.986559715 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPGLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1328|beta-lactamase_S281N|0.986543393 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGANLIKHW +>1329|beta-lactamase_M153T|0.986543393 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNTGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1330|beta-lactamase_A222M|0.986543393 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSMLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1331|beta-lactamase_A16Q|0.986543393 +MSIQHFRVALIPFFAQFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1332|beta-lactamase_Q86R|0.98648016 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGREQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1333|beta-lactamase_P172S|0.986447224 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAISNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1334|beta-lactamase_E166R|0.986421814 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPRLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1335|beta-lactamase_A182H|0.986399629 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPHAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1336|beta-lactamase_L10V|0.986399629 +MSIQHFRVAVIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1337|beta-lactamase_T193L|0.986293393 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLLGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1338|beta-lactamase_E102T|0.986293393 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVTYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1339|beta-lactamase_E56T|0.986236708 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILTSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1340|beta-lactamase_S254V|0.986192533 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPVRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1341|beta-lactamase_K144C|0.986146892 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPCELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1342|beta-lactamase_S221H|0.986110633 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRHALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1343|beta-lactamase_S281L|0.986050625 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGALLIKHW +>1344|beta-lactamase_K213C|0.985982506 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADCVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1345|beta-lactamase_D269K|0.985955434 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMKERNRQIAEIGASLIKHW +>1346|beta-lactamase_A266T|0.985805317 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQTTMDERNRQIAEIGASLIKHW +>1347|beta-lactamase_S96D|0.985796716 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYDQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1348|beta-lactamase_T139S|0.9857155 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTSIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1349|beta-lactamase_H110H|0.985587601 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1350|beta-lactamase_A77Y|0.985585223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGYVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1351|beta-lactamase_A276F|0.985585223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIFEIGASLIKHW +>1352|beta-lactamase_V101I|0.985585223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLIEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1353|beta-lactamase_T198H|0.985585223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLHLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1354|beta-lactamase_E270I|0.985585223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDIRNRQIAEIGASLIKHW +>1355|beta-lactamase_Q203L|0.985585223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRLQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1356|beta-lactamase_K32H|0.985585223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVHDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1357|beta-lactamase_H156E|0.985585223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDEVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1358|beta-lactamase_A9H|0.985585223 +MSIQHFRVHLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1359|beta-lactamase_F22Q|0.985585223 +MSIQHFRVALIPFFAAFCLPVQAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1360|beta-lactamase_L150C|0.985528831 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFCHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1361|beta-lactamase_N173Y|0.985443511 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPYDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1362|beta-lactamase_M66L|0.985330629 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPLMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1363|beta-lactamase_E145Q|0.98531812 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKQLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1364|beta-lactamase_K252I|0.98531812 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGIPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1365|beta-lactamase_L199R|0.985288995 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTRASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1366|beta-lactamase_R238G|0.985275508 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEGGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1367|beta-lactamase_V29L|0.985252737 +MSIQHFRVALIPFFAAFCLPVFAHPETLLKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1368|beta-lactamase_P172Q|0.985226446 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIQNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1369|beta-lactamase_P60V|0.985003421 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRVEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1370|beta-lactamase_I275V|0.984844801 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQVAEIGASLIKHW +>1371|beta-lactamase_I45A|0.984727912 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYAELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1372|beta-lactamase_K32S|0.984727912 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVSDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1373|beta-lactamase_N98V|0.984727912 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQVDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1374|beta-lactamase_Q265Y|0.984727912 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSYATMDERNRQIAEIGASLIKHW +>1375|beta-lactamase_A9K|0.984727912 +MSIQHFRVKLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1376|beta-lactamase_F17T|0.984727912 +MSIQHFRVALIPFFAATCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1377|beta-lactamase_K144M|0.984654418 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPMELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1378|beta-lactamase_S80M|0.984627052 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLMRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1379|beta-lactamase_R255K|0.984627052 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSKIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1380|beta-lactamase_A133G|0.984603987 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAGNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1381|beta-lactamase_N50L|0.984567142 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLLSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1382|beta-lactamase_L167M|0.984461787 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEMNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1383|beta-lactamase_T267N|0.984260262 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQANMDERNRQIAEIGASLIKHW +>1384|beta-lactamase_K144V|0.984151779 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPVELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1385|beta-lactamase_P172M|0.984104378 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIMNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1386|beta-lactamase_S221N|0.984069977 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRNALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1387|beta-lactamase_P172I|0.984069977 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIINDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1388|beta-lactamase_D48E|0.98402326 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELELNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1389|beta-lactamase_H94S|0.984008894 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRISYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1390|beta-lactamase_E108G|0.983923084 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTGKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1391|beta-lactamase_Y44F|0.983824277 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGFIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1392|beta-lactamase_E87M|0.983668882 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQMQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1393|beta-lactamase_I125V|0.983637608 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAVTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1394|beta-lactamase_G39D|0.983630571 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLDARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1395|beta-lactamase_A183H|0.98359871 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAHMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1396|beta-lactamase_I54T|0.98359871 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKTLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1397|beta-lactamase_P12N|0.98359871 +MSIQHFRVALINFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1398|beta-lactamase_G85H|0.983549062 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAHQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1399|beta-lactamase_E277D|0.983512119 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIADIGASLIKHW +>1400|beta-lactamase_E175F|0.983441947 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDFRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1401|beta-lactamase_W163C|0.983392494 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRCEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1402|beta-lactamase_E56K|0.983383991 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILKSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1403|beta-lactamase_A276K|0.98325821 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIKEIGASLIKHW +>1404|beta-lactamase_Q204S|0.98325821 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQSLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1405|beta-lactamase_V157S|0.98325821 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHSTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1406|beta-lactamase_D207W|0.98325821 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIWWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1407|beta-lactamase_R159H|0.98325821 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTHLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1408|beta-lactamase_E270F|0.98325821 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDFRNRQIAEIGASLIKHW +>1409|beta-lactamase_H151E|0.98325821 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLENMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1410|beta-lactamase_D269F|0.98325821 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMFERNRQIAEIGASLIKHW +>1411|beta-lactamase_R273L|0.98325821 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNLQIAEIGASLIKHW +>1412|beta-lactamase_K109D|0.98325821 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEDHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1413|beta-lactamase_E195R|0.98325821 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGRLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1414|beta-lactamase_Q265M|0.98325821 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSMATMDERNRQIAEIGASLIKHW +>1415|beta-lactamase_A9I|0.98325821 +MSIQHFRVILIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1416|beta-lactamase_N173H|0.983093921 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPHDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1417|beta-lactamase_E61A|0.983079261 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPAERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1418|beta-lactamase_T178S|0.982998436 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDSTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1419|beta-lactamase_D250Y|0.982950254 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPYGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1420|beta-lactamase_K30L|0.982933542 +MSIQHFRVALIPFFAAFCLPVFAHPETLVLVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1421|beta-lactamase_L55Y|0.982933542 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIYESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1422|beta-lactamase_L223I|0.982922596 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAIPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1423|beta-lactamase_L188M|0.982776779 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTMRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1424|beta-lactamase_T126E|0.982776779 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIEMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1425|beta-lactamase_A200Y|0.982776779 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLYSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1426|beta-lactamase_A246Y|0.98269527 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAYLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1427|beta-lactamase_Q88L|0.982631548 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQELLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1428|beta-lactamase_P60C|0.982623632 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRCEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1429|beta-lactamase_K109V|0.982623632 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEVHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1430|beta-lactamase_S80T|0.982607701 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLTRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1431|beta-lactamase_E61S|0.982575352 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPSERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1432|beta-lactamase_T126G|0.982568706 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIGMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1433|beta-lactamase_A246F|0.982531079 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAFLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1434|beta-lactamase_R189G|0.982526583 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLGKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1435|beta-lactamase_P12V|0.982503518 +MSIQHFRVALIVFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1436|beta-lactamase_G90V|0.982359656 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLVRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1437|beta-lactamase_A77M|0.982327404 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGMVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1438|beta-lactamase_G90W|0.982327404 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLWRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1439|beta-lactamase_T198E|0.982327404 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLELASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1440|beta-lactamase_H156W|0.982327404 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDWVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1441|beta-lactamase_N152F|0.982327404 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHFMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1442|beta-lactamase_K252T|0.982241106 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGTPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1443|beta-lactamase_V31I|0.982204457 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKIKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1444|beta-lactamase_P12G|0.982204457 +MSIQHFRVALIGFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1445|beta-lactamase_S57G|0.982186777 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEGFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1446|beta-lactamase_N50I|0.982155991 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLISGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1447|beta-lactamase_N50V|0.982155991 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLVSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1448|beta-lactamase_K30R|0.982113868 +MSIQHFRVALIPFFAAFCLPVFAHPETLVRVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1449|beta-lactamase_A246T|0.982100968 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIATLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1450|beta-lactamase_P253C|0.982044185 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKCSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1451|beta-lactamase_A9C|0.982044185 +MSIQHFRVCLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1452|beta-lactamase_K252N|0.982022 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGNPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1453|beta-lactamase_D269M|0.98196551 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMMERNRQIAEIGASLIKHW +>1454|beta-lactamase_K213S|0.981907066 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADSVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1455|beta-lactamase_E145T|0.981826241 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKTLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1456|beta-lactamase_S80G|0.9817418 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLGRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1457|beta-lactamase_H94E|0.981735154 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIEYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1458|beta-lactamase_S254R|0.98170691 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPRRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1459|beta-lactamase_S96H|0.981685115 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYHQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1460|beta-lactamase_H24Q|0.98165345 +MSIQHFRVALIPFFAAFCLPVFAQPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1461|beta-lactamase_E277A|0.981593931 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAAIGASLIKHW +>1462|beta-lactamase_P12L|0.98157976 +MSIQHFRVALILFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1463|beta-lactamase_A280C|0.981513008 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGCSLIKHW +>1464|beta-lactamase_H110F|0.981513008 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKFLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1465|beta-lactamase_D207N|0.981513008 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLINWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1466|beta-lactamase_T138I|0.981513008 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLITIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1467|beta-lactamase_E237H|0.981513008 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGHRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1468|beta-lactamase_Q86M|0.981513008 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGMEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1469|beta-lactamase_H156L|0.981513008 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDLVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1470|beta-lactamase_H156S|0.981513008 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDSVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1471|beta-lactamase_F14M|0.981513008 +MSIQHFRVALIPFMAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1472|beta-lactamase_L10I|0.981513008 +MSIQHFRVAIIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1473|beta-lactamase_S2F|0.981513008 +MFIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1474|beta-lactamase_S57Y|0.981428763 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEYFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1475|beta-lactamase_S57T|0.981354388 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILETFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1476|beta-lactamase_F13V|0.981325068 +MSIQHFRVALIPVFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1477|beta-lactamase_A183S|0.981249326 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPASMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1478|beta-lactamase_T139L|0.981024345 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTLIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1479|beta-lactamase_F149M|0.981024345 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAMLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1480|beta-lactamase_M67D|0.981013692 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMDSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1481|beta-lactamase_K252Q|0.98079438 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGQPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1482|beta-lactamase_S80A|0.980738966 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLARVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1483|beta-lactamase_E277N|0.980698602 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIANIGASLIKHW +>1484|beta-lactamase_T198Q|0.980660682 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLQLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1485|beta-lactamase_L223M|0.980612793 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAMPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1486|beta-lactamase_L191F|0.980573309 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKFLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1487|beta-lactamase_E108S|0.980573309 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTSKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1488|beta-lactamase_G226S|0.980482711 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPASWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1489|beta-lactamase_E102R|0.980465901 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVRYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1490|beta-lactamase_E169V|0.980402375 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNVAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1491|beta-lactamase_E270R|0.980308552 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDRRNRQIAEIGASLIKHW +>1492|beta-lactamase_T198G|0.980257144 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLGLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1493|beta-lactamase_R238S|0.980256069 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGESGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1494|beta-lactamase_S221V|0.980179349 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRVALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1495|beta-lactamase_L120M|0.9801556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREMCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1496|beta-lactamase_A170W|0.9801556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEWIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1497|beta-lactamase_S281M|0.9801556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAMLIKHW +>1498|beta-lactamase_T116E|0.9801556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMEVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1499|beta-lactamase_A266N|0.9801556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQNTMDERNRQIAEIGASLIKHW +>1500|beta-lactamase_M180F|0.9801556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTFPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1501|beta-lactamase_T147V|0.9801556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELVAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1502|beta-lactamase_A84K|0.9801556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDKGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1503|beta-lactamase_D207V|0.9801556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIVWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1504|beta-lactamase_E108H|0.9801556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTHKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1505|beta-lactamase_L199K|0.9801556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTKASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1506|beta-lactamase_N98M|0.9801556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQMDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1507|beta-lactamase_P25V|0.9801556 +MSIQHFRVALIPFFAAFCLPVFAHVETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1508|beta-lactamase_V8M|0.9801556 +MSIQHFRMALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1509|beta-lactamase_R92T|0.980070084 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRTIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1510|beta-lactamase_P172R|0.980014279 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIRNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1511|beta-lactamase_H94D|0.979973133 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIDYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1512|beta-lactamase_I275M|0.979767797 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQMAEIGASLIKHW +>1513|beta-lactamase_S96F|0.979767797 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYFQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1514|beta-lactamase_T267H|0.979767797 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAHMDERNRQIAEIGASLIKHW +>1515|beta-lactamase_L199T|0.979767797 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTTASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1516|beta-lactamase_F14V|0.979733884 +MSIQHFRVALIPFVAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1517|beta-lactamase_I54E|0.97958406 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKELESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1518|beta-lactamase_I54M|0.97958406 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKMLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1519|beta-lactamase_H151S|0.97958406 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLSNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1520|beta-lactamase_K213N|0.97951682 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADNVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1521|beta-lactamase_E166A|0.979476945 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPALNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1522|beta-lactamase_A280T|0.979450459 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGTSLIKHW +>1523|beta-lactamase_V8A|0.979450459 +MSIQHFRAALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1524|beta-lactamase_G251S|0.979427297 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDSKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1525|beta-lactamase_A222G|0.979416644 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSGLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1526|beta-lactamase_M153V|0.979406675 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNVGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1527|beta-lactamase_M127Q|0.979406675 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITQSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1528|beta-lactamase_Q265P|0.979406675 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSPATMDERNRQIAEIGASLIKHW +>1529|beta-lactamase_Q86N|0.979357125 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGNEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1530|beta-lactamase_Q203I|0.97932028 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRIQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1531|beta-lactamase_L167C|0.979269165 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPECNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1532|beta-lactamase_T262S|0.979269165 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTSGSQATMDERNRQIAEIGASLIKHW +>1533|beta-lactamase_K32L|0.979269165 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVLDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1534|beta-lactamase_T126C|0.979069693 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAICMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1535|beta-lactamase_A84C|0.979069693 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDCGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1536|beta-lactamase_S221M|0.979069693 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRMALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1537|beta-lactamase_A183E|0.97895603 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAEMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1538|beta-lactamase_S80E|0.978831323 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLERVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1539|beta-lactamase_A84A|0.978772882 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1540|beta-lactamase_S80S|0.978748296 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1541|beta-lactamase_E169H|0.978693814 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNHAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1542|beta-lactamase_E145D|0.978693814 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKDLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1543|beta-lactamase_N152N|0.978665223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1544|beta-lactamase_A124T|0.978653841 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSATITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1545|beta-lactamase_P172Y|0.97860429 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIYNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1546|beta-lactamase_H151T|0.97860429 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLTNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1547|beta-lactamase_S2K|0.97860429 +MKIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1548|beta-lactamase_V31L|0.978458864 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKLKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1549|beta-lactamase_A148F|0.978458864 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTFFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1550|beta-lactamase_D269R|0.978458864 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMRERNRQIAEIGASLIKHW +>1551|beta-lactamase_E108R|0.978458864 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTRKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1552|beta-lactamase_M180G|0.978398954 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTGPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1553|beta-lactamase_L38M|0.978387813 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQMGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1554|beta-lactamase_I256L|0.978290276 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRLVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1555|beta-lactamase_T147R|0.978283337 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELRAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1556|beta-lactamase_T107S|0.978181206 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVSEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1557|beta-lactamase_L28V|0.978181206 +MSIQHFRVALIPFFAAFCLPVFAHPETVVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1558|beta-lactamase_P217N|0.978181206 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGNLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1559|beta-lactamase_V29M|0.978181206 +MSIQHFRVALIPFFAAFCLPVFAHPETLMKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1560|beta-lactamase_L199F|0.978181206 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTFASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1561|beta-lactamase_Q97W|0.978181206 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSWNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1562|beta-lactamase_K284I|0.978181206 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIIHW +>1563|beta-lactamase_F22G|0.978181206 +MSIQHFRVALIPFFAAFCLPVGAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1564|beta-lactamase_Q4C|0.978181206 +MSICHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1565|beta-lactamase_L146F|0.977983786 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEFTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1566|beta-lactamase_E169R|0.977935799 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNRAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1567|beta-lactamase_E169N|0.977919869 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNNAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1568|beta-lactamase_E108K|0.977919869 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTKKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1569|beta-lactamase_T187N|0.977794967 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATNLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1570|beta-lactamase_S96K|0.977794967 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYKQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1571|beta-lactamase_Q88V|0.977794967 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEVLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1572|beta-lactamase_I125M|0.977721667 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAMTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1573|beta-lactamase_T198A|0.977698798 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLALASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1574|beta-lactamase_A170F|0.977673485 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEFIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1575|beta-lactamase_A280L|0.977673485 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGLSLIKHW +>1576|beta-lactamase_L79M|0.97757888 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVMSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1577|beta-lactamase_W163E|0.97757888 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDREEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1578|beta-lactamase_A77L|0.977440784 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGLVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1579|beta-lactamase_A182Q|0.977440784 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPQAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1580|beta-lactamase_A280W|0.977440784 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGWSLIKHW +>1581|beta-lactamase_T193F|0.977440784 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLFGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1582|beta-lactamase_A84I|0.977440784 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDIGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1583|beta-lactamase_L199S|0.977440784 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTSASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1584|beta-lactamase_H156V|0.977440784 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDVVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1585|beta-lactamase_E166T|0.977307281 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPTLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1586|beta-lactamase_E237T|0.977274638 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGTRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1587|beta-lactamase_I11F|0.977274638 +MSIQHFRVALFPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1588|beta-lactamase_L247I|0.97722069 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAIGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1589|beta-lactamase_E277L|0.97722069 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIALIGASLIKHW +>1590|beta-lactamase_W163L|0.977205444 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRLEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1591|beta-lactamase_T158S|0.977178079 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVSRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1592|beta-lactamase_M66I|0.977115041 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPIMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1593|beta-lactamase_Q204V|0.977070573 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQVLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1594|beta-lactamase_M268F|0.977070573 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATFDERNRQIAEIGASLIKHW +>1595|beta-lactamase_Q203D|0.977012129 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRDQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1596|beta-lactamase_S96V|0.976991898 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYVQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1597|beta-lactamase_L160A|0.976961699 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRADRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1598|beta-lactamase_F17I|0.976961699 +MSIQHFRVALIPFFAAICLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1599|beta-lactamase_V101A|0.976814318 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLAEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1600|beta-lactamase_G226H|0.976814318 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAHWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1601|beta-lactamase_Q37C|0.976814318 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDCLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1602|beta-lactamase_S122W|0.976626378 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCWAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1603|beta-lactamase_K213V|0.976626378 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADVVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1604|beta-lactamase_A9G|0.976589924 +MSIQHFRVGLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1605|beta-lactamase_R189N|0.976535878 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLNKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1606|beta-lactamase_R41M|0.976535878 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAMVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1607|beta-lactamase_E210K|0.976535878 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMKADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1608|beta-lactamase_L73A|0.976482613 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVALCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1609|beta-lactamase_R271A|0.976447625 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEANRQIAEIGASLIKHW +>1610|beta-lactamase_G90I|0.976447625 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLIRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1611|beta-lactamase_H110Y|0.976447625 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKYLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1612|beta-lactamase_K213I|0.976404232 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADIVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1613|beta-lactamase_R271T|0.976378528 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDETNRQIAEIGASLIKHW +>1614|beta-lactamase_A84D|0.976322918 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDDGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1615|beta-lactamase_L150M|0.976277375 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFMHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1616|beta-lactamase_A276C|0.976277375 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQICEIGASLIKHW +>1617|beta-lactamase_T139D|0.976277375 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTDIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1618|beta-lactamase_N152C|0.976277375 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHCMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1619|beta-lactamase_N152L|0.976277375 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHLMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1620|beta-lactamase_K109I|0.976114943 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEIHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1621|beta-lactamase_Q204H|0.976083376 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQHLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1622|beta-lactamase_M127F|0.976036659 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITFSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1623|beta-lactamase_D250T|0.976003528 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPTGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1624|beta-lactamase_E277V|0.975874619 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAVIGASLIKHW +>1625|beta-lactamase_S80L|0.975829369 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLLRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1626|beta-lactamase_A77V|0.975811972 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGVVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1627|beta-lactamase_D113S|0.975811972 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTSGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1628|beta-lactamase_E102V|0.975811972 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVVYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1629|beta-lactamase_C18S|0.975811972 +MSIQHFRVALIPFFAAFSLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1630|beta-lactamase_S80R|0.975761249 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLRRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1631|beta-lactamase_L247V|0.975705151 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAVGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1632|beta-lactamase_E56N|0.975705151 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILNSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1633|beta-lactamase_E56Q|0.975705151 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILQSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1634|beta-lactamase_I11M|0.975601749 +MSIQHFRVALMPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1635|beta-lactamase_T147S|0.975561386 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELSAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1636|beta-lactamase_N168G|0.975546726 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELGEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1637|beta-lactamase_I243V|0.975508219 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGVIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1638|beta-lactamase_L73M|0.97540472 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVMLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1639|beta-lactamase_D207M|0.97540472 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIMWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1640|beta-lactamase_D113Y|0.97540472 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTYGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1641|beta-lactamase_E102S|0.97540472 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVSYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1642|beta-lactamase_Q88M|0.97540472 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEMLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1643|beta-lactamase_P25T|0.975341781 +MSIQHFRVALIPFFAAFCLPVFAHTETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1644|beta-lactamase_E108D|0.975280014 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTDKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1645|beta-lactamase_Y44L|0.975235936 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGLIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1646|beta-lactamase_H285R|0.975235936 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKRW +>1647|beta-lactamase_A200I|0.975219615 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLISRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1648|beta-lactamase_F13Y|0.975160389 +MSIQHFRVALIPYFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1649|beta-lactamase_D269C|0.975131167 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMCERNRQIAEIGASLIKHW +>1650|beta-lactamase_R162N|0.975045455 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDNWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1651|beta-lactamase_M180W|0.975045455 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTWPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1652|beta-lactamase_H285C|0.975045455 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKCW +>1653|beta-lactamase_G39Q|0.975045455 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLQARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1654|beta-lactamase_D113H|0.975045455 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTHGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1655|beta-lactamase_Q86G|0.974978606 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGGEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1656|beta-lactamase_A124S|0.974881167 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSASITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1657|beta-lactamase_K144P|0.974828489 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPPELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1658|beta-lactamase_Y95I|0.974579271 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHISQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1659|beta-lactamase_L160S|0.974543794 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRSDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1660|beta-lactamase_A200V|0.97453881 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLVSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1661|beta-lactamase_E87L|0.974462871 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQLQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1662|beta-lactamase_I283M|0.974440295 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLMKHW +>1663|beta-lactamase_E62T|0.974440295 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPETRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1664|beta-lactamase_I54H|0.974440295 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKHLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1665|beta-lactamase_G216A|0.974308356 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAAPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1666|beta-lactamase_T267M|0.974308356 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAMMDERNRQIAEIGASLIKHW +>1667|beta-lactamase_R271I|0.974183063 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEINRQIAEIGASLIKHW +>1668|beta-lactamase_L196D|0.974183063 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEDLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1669|beta-lactamase_W163N|0.974183063 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRNEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1670|beta-lactamase_K32I|0.974183063 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVIDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1671|beta-lactamase_F13W|0.974183063 +MSIQHFRVALIPWFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1672|beta-lactamase_I3Q|0.974183063 +MSQQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1673|beta-lactamase_V82C|0.974148368 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRCDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1674|beta-lactamase_E166C|0.974122762 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPCLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1675|beta-lactamase_M127L|0.974114259 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITLSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1676|beta-lactamase_Q274R|0.974063829 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRRIAEIGASLIKHW +>1677|beta-lactamase_D113G|0.973995123 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTGGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1678|beta-lactamase_G76S|0.973950362 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCSAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1679|beta-lactamase_G39C|0.973950362 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLCARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1680|beta-lactamase_E169Y|0.973950362 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNYAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1681|beta-lactamase_G251D|0.973895631 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDDKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1682|beta-lactamase_E87I|0.973842172 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQIQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1683|beta-lactamase_G194P|0.973738868 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTPELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1684|beta-lactamase_S80V|0.973738868 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLVRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1685|beta-lactamase_T267R|0.973738868 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQARMDERNRQIAEIGASLIKHW +>1686|beta-lactamase_N98D|0.973738868 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQDDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1687|beta-lactamase_F13I|0.973738868 +MSIQHFRVALIPIFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1688|beta-lactamase_R7P|0.973738868 +MSIQHFPVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1689|beta-lactamase_I243L|0.973640061 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGLIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1690|beta-lactamase_V117L|0.973640061 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTLRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1691|beta-lactamase_G90Q|0.973545651 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLQRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1692|beta-lactamase_A133T|0.973368657 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTATNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1693|beta-lactamase_E195K|0.973368657 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGKLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1694|beta-lactamase_L137M|0.973297215 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLMTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1695|beta-lactamase_A235G|0.973285487 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGGGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1696|beta-lactamase_H94A|0.973231929 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIAYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1697|beta-lactamase_S57W|0.973205737 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEWFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1698|beta-lactamase_M127Y|0.973205737 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITYSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1699|beta-lactamase_G194C|0.973129115 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTCELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1700|beta-lactamase_F6V|0.973129115 +MSIQHVRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1701|beta-lactamase_G251Q|0.973055424 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDQKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1702|beta-lactamase_E169C|0.973055424 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNCAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1703|beta-lactamase_G194A|0.97298447 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTAELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1704|beta-lactamase_S96Y|0.972970592 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYYQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1705|beta-lactamase_V82I|0.972931108 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1706|beta-lactamase_L89M|0.972786855 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQMGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1707|beta-lactamase_I11Y|0.972725674 +MSIQHFRVALYPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1708|beta-lactamase_K30V|0.972666546 +MSIQHFRVALIPFFAAFCLPVFAHPETLVVVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1709|beta-lactamase_E56S|0.97262071 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILSSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1710|beta-lactamase_S221C|0.97257243 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRCALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1711|beta-lactamase_G85E|0.972554154 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAEQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1712|beta-lactamase_D36D|0.972514635 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1713|beta-lactamase_S221I|0.972513986 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRIALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1714|beta-lactamase_G226D|0.972449091 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPADWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1715|beta-lactamase_K53G|0.972350577 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGGILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1716|beta-lactamase_D48D|0.972317819 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1717|beta-lactamase_T147N|0.972288223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELNAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1718|beta-lactamase_E166H|0.972170944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPHLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1719|beta-lactamase_G39L|0.972088751 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLLARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1720|beta-lactamase_F14T|0.971937852 +MSIQHFRVALIPFTAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1721|beta-lactamase_G279A|0.971868364 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIAASLIKHW +>1722|beta-lactamase_G85N|0.971868364 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDANQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1723|beta-lactamase_A200M|0.971868364 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLMSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1724|beta-lactamase_P25S|0.971868364 +MSIQHFRVALIPFFAAFCLPVFAHSETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1725|beta-lactamase_W163K|0.971834939 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRKEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1726|beta-lactamase_P217T|0.971680131 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGTLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1727|beta-lactamase_V257I|0.971651398 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIIVIYTTGSQATMDERNRQIAEIGASLIKHW +>1728|beta-lactamase_V8D|0.971569302 +MSIQHFRDALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1729|beta-lactamase_H156P|0.97129096 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDPVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1730|beta-lactamase_A16T|0.971251085 +MSIQHFRVALIPFFATFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1731|beta-lactamase_G251E|0.971057379 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDEKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1732|beta-lactamase_L160C|0.970952903 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRCDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1733|beta-lactamase_R7G|0.970898563 +MSIQHFGVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1734|beta-lactamase_D113R|0.970800049 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTRGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1735|beta-lactamase_E169E|0.970798035 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1736|beta-lactamase_I283F|0.970755092 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLFKHW +>1737|beta-lactamase_I256V|0.970666546 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRVVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1738|beta-lactamase_R118K|0.970653841 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVKELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1739|beta-lactamase_F58L|0.970407066 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESLRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1740|beta-lactamase_L282C|0.970394556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASCIKHW +>1741|beta-lactamase_L55V|0.970303958 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIVESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1742|beta-lactamase_M67T|0.970131753 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMTSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1743|beta-lactamase_Y260L|0.970124717 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVILTTGSQATMDERNRQIAEIGASLIKHW +>1744|beta-lactamase_Q88I|0.969911073 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEILGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1745|beta-lactamase_L146V|0.96990345 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEVTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1746|beta-lactamase_W163R|0.969638204 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRREPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1747|beta-lactamase_A245C|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIICALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1748|beta-lactamase_C75A|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLAGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1749|beta-lactamase_T261L|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYLTGSQATMDERNRQIAEIGASLIKHW +>1750|beta-lactamase_A77H|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGHVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1751|beta-lactamase_E46A|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIALDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1752|beta-lactamase_S264G|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGGQATMDERNRQIAEIGASLIKHW +>1753|beta-lactamase_Q274I|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRIIAEIGASLIKHW +>1754|beta-lactamase_Q274S|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRSIAEIGASLIKHW +>1755|beta-lactamase_T116S|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMSVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1756|beta-lactamase_R271Q|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEQNRQIAEIGASLIKHW +>1757|beta-lactamase_G194N|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTNELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1758|beta-lactamase_F228M|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWMIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1759|beta-lactamase_T139G|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTGIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1760|beta-lactamase_V106Q|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPQTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1761|beta-lactamase_Q204I|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQILIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1762|beta-lactamase_A211M|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEMDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1763|beta-lactamase_V101S|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLSEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1764|beta-lactamase_G251M|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDMKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1765|beta-lactamase_L111C|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHCTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1766|beta-lactamase_D33S|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKSAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1767|beta-lactamase_T193W|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLWGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1768|beta-lactamase_S51Q|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNQGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1769|beta-lactamase_E169I|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNIAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1770|beta-lactamase_A84M|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDMGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1771|beta-lactamase_G85Q|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAQQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1772|beta-lactamase_R41P|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAPVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1773|beta-lactamase_R41Y|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAYVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1774|beta-lactamase_P172K|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIKNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1775|beta-lactamase_E210A|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMAADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1776|beta-lactamase_E210F|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMFADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1777|beta-lactamase_E210H|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMHADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1778|beta-lactamase_E210M|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMMADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1779|beta-lactamase_E210R|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMRADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1780|beta-lactamase_E210Y|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMYADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1781|beta-lactamase_I54A|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKALESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1782|beta-lactamase_R176M|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEMDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1783|beta-lactamase_T138F|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLFTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1784|beta-lactamase_T138W|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLWTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1785|beta-lactamase_E145F|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKFLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1786|beta-lactamase_E108N|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTNKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1787|beta-lactamase_E108Q|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTQKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1788|beta-lactamase_D113M|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTMGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1789|beta-lactamase_K32V|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVVDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1790|beta-lactamase_R92M|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRMIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1791|beta-lactamase_R92Y|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRYIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1792|beta-lactamase_Q86F|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGFEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1793|beta-lactamase_T112C|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLCDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1794|beta-lactamase_R273Q|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNQQIAEIGASLIKHW +>1795|beta-lactamase_R273V|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNVQIAEIGASLIKHW +>1796|beta-lactamase_E102L|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVLYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1797|beta-lactamase_E102N|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVNYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1798|beta-lactamase_K284H|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIHHW +>1799|beta-lactamase_K284M|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIMHW +>1800|beta-lactamase_Q265W|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSWATMDERNRQIAEIGASLIKHW +>1801|beta-lactamase_F17A|0.969296433 +MSIQHFRVALIPFFAAACLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1802|beta-lactamase_F22M|0.969296433 +MSIQHFRVALIPFFAAFCLPVMAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1803|beta-lactamase_F22R|0.969296433 +MSIQHFRVALIPFFAAFCLPVRAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1804|beta-lactamase_L19D|0.969296433 +MSIQHFRVALIPFFAAFCDPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1805|beta-lactamase_P25M|0.969296433 +MSIQHFRVALIPFFAAFCLPVFAHMETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1806|beta-lactamase_Q4I|0.969296433 +MSIIHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1807|beta-lactamase_G251R|0.968486523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDRKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1808|beta-lactamase_G85K|0.968210526 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAKQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1809|beta-lactamase_L192V|0.968074775 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLVTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1810|beta-lactamase_K284V|0.967975674 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIVHW +>1811|beta-lactamase_M268I|0.967900225 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATIDERNRQIAEIGASLIKHW +>1812|beta-lactamase_E270L|0.967815588 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDLRNRQIAEIGASLIKHW +>1813|beta-lactamase_T198D|0.967581812 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLDLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1814|beta-lactamase_P165T|0.967511347 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWETELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1815|beta-lactamase_K284G|0.967452414 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIGHW +>1816|beta-lactamase_A222H|0.967380092 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSHLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1817|beta-lactamase_P217S|0.967288223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGSLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1818|beta-lactamase_D250V|0.967143774 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPVGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1819|beta-lactamase_E164E|0.967134682 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1820|beta-lactamase_Q37G|0.967075264 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDGLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1821|beta-lactamase_L218M|0.967023563 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPMLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1822|beta-lactamase_I3F|0.967023563 +MSFQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1823|beta-lactamase_E145I|0.966912735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKILTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1824|beta-lactamase_F6L|0.966790471 +MSIQHLRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1825|beta-lactamase_G226K|0.966757926 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAKWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1826|beta-lactamase_I229C|0.966655014 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFCADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1827|beta-lactamase_P172C|0.966655014 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAICNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1828|beta-lactamase_I259L|0.966530405 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVLYTTGSQATMDERNRQIAEIGASLIKHW +>1829|beta-lactamase_T138L|0.966463556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLLTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1830|beta-lactamase_D207I|0.966421921 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIIWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1831|beta-lactamase_E277K|0.966421921 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAKIGASLIKHW +>1832|beta-lactamase_E210N|0.966334842 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMNADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1833|beta-lactamase_K252F|0.966242289 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGFPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1834|beta-lactamase_P172H|0.966081519 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIHNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1835|beta-lactamase_I3T|0.966081519 +MSTQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1836|beta-lactamase_G39V|0.966065588 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLVARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1837|beta-lactamase_M180D|0.966038712 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTDPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1838|beta-lactamase_E210T|0.966038712 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMTADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1839|beta-lactamase_A225F|0.966038712 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPFGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1840|beta-lactamase_N152V|0.965926319 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHVMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1841|beta-lactamase_L10C|0.965806011 +MSIQHFRVACIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1842|beta-lactamase_H285Q|0.965729584 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKQW +>1843|beta-lactamase_S96I|0.96567671 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYIQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1844|beta-lactamase_E277G|0.96567671 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAGIGASLIKHW +>1845|beta-lactamase_R238W|0.965537441 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEWGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1846|beta-lactamase_L150L|0.965525441 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1847|beta-lactamase_E277Q|0.965387129 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAQIGASLIKHW +>1848|beta-lactamase_M153N|0.965224208 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNNGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1849|beta-lactamase_G216M|0.965224208 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAMPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1850|beta-lactamase_R7K|0.965224208 +MSIQHFKVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1851|beta-lactamase_S80I|0.965092856 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLIRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1852|beta-lactamase_H156F|0.965047215 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDFVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1853|beta-lactamase_K53F|0.964952805 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGFILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1854|beta-lactamase_L191I|0.964903939 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKILTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1855|beta-lactamase_E62D|0.964853997 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEDRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1856|beta-lactamase_R41N|0.964853997 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGANVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1857|beta-lactamase_S254L|0.964662539 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPLRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1858|beta-lactamase_P217E|0.964529036 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGELLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1859|beta-lactamase_Q4A|0.964409803 +MSIAHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1860|beta-lactamase_R162H|0.964327023 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1861|beta-lactamase_T139R|0.964327023 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTRIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1862|beta-lactamase_T126A|0.964266038 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIAMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1863|beta-lactamase_T267C|0.964241312 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQACMDERNRQIAEIGASLIKHW +>1864|beta-lactamase_D207C|0.96415257 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLICWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1865|beta-lactamase_F22Y|0.96415257 +MSIQHFRVALIPFFAAFCLPVYAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1866|beta-lactamase_A77A|0.964135807 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1867|beta-lactamase_H110R|0.964042035 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKRLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1868|beta-lactamase_G279S|0.963965608 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEISASLIKHW +>1869|beta-lactamase_Q86C|0.963965608 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGCEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1870|beta-lactamase_R189M|0.9638668 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLMKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1871|beta-lactamase_I11A|0.963729388 +MSIQHFRVALAPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1872|beta-lactamase_R92H|0.96367153 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRHIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1873|beta-lactamase_G90F|0.96354741 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLFRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1874|beta-lactamase_S80D|0.963389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLDRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1875|beta-lactamase_E237W|0.963373251 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGWRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1876|beta-lactamase_T131A|0.963312852 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNAAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1877|beta-lactamase_T107A|0.963282164 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVAEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1878|beta-lactamase_S221E|0.96322802 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLREALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1879|beta-lactamase_A77K|0.963188145 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGKVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1880|beta-lactamase_E46N|0.963188145 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYINLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1881|beta-lactamase_M153H|0.963188145 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNHGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1882|beta-lactamase_E119G|0.963188145 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRGLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1883|beta-lactamase_Q88G|0.963188145 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEGLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1884|beta-lactamase_K252G|0.963188145 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGGPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1885|beta-lactamase_E277S|0.962950166 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIASIGASLIKHW +>1886|beta-lactamase_G85S|0.962902668 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDASQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1887|beta-lactamase_T262C|0.962780893 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTCGSQATMDERNRQIAEIGASLIKHW +>1888|beta-lactamase_T112M|0.962780893 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLMDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1889|beta-lactamase_P217H|0.962670455 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGHLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1890|beta-lactamase_M67V|0.962660291 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMVSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1891|beta-lactamase_A222P|0.962632828 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSPLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1892|beta-lactamase_L135V|0.962556206 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANVLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1893|beta-lactamase_S96M|0.962477922 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYMQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1894|beta-lactamase_Q88C|0.962438047 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQECLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1895|beta-lactamase_V157L|0.962315491 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHLTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1896|beta-lactamase_K252L|0.962231441 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGLPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1897|beta-lactamase_W163T|0.962214337 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRTEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1898|beta-lactamase_V8E|0.96214524 +MSIQHFREALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1899|beta-lactamase_Q86W|0.962056988 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGWEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1900|beta-lactamase_S254I|0.961778548 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPIRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1901|beta-lactamase_W163P|0.961778548 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRPEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1902|beta-lactamase_G85D|0.961609568 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDADQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1903|beta-lactamase_I3S|0.961546726 +MSSQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1904|beta-lactamase_G251T|0.961512422 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDTKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1905|beta-lactamase_M67S|0.961477824 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMSSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1906|beta-lactamase_H24L|0.961477824 +MSIQHFRVALIPFFAAFCLPVFALPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1907|beta-lactamase_G85R|0.961358786 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDARQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1908|beta-lactamase_S96C|0.961318227 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYCQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1909|beta-lactamase_F6Y|0.961285584 +MSIQHYRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1910|beta-lactamase_C75T|0.961152082 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLTGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1911|beta-lactamase_Q204K|0.961152082 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQKLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1912|beta-lactamase_E277M|0.961152082 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAMIGASLIKHW +>1913|beta-lactamase_R118M|0.961152082 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVMELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1914|beta-lactamase_H5N|0.961152082 +MSIQNFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1915|beta-lactamase_P12Q|0.960998348 +MSIQHFRVALIQFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1916|beta-lactamase_W163S|0.960978802 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRSEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1917|beta-lactamase_L55F|0.960953391 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIFESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1918|beta-lactamase_A34C|0.960797899 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDCEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1919|beta-lactamase_H285E|0.960797899 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKEW +>1920|beta-lactamase_A276T|0.960764181 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQITEIGASLIKHW +>1921|beta-lactamase_D250W|0.96074483 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPWGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1922|beta-lactamase_F70A|0.960672996 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTAKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1923|beta-lactamase_R238L|0.960667035 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGELGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1924|beta-lactamase_S254Y|0.960591487 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPYRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1925|beta-lactamase_A77F|0.960411659 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGFVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1926|beta-lactamase_A276Y|0.960411659 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIYEIGASLIKHW +>1927|beta-lactamase_R271V|0.960411659 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEVNRQIAEIGASLIKHW +>1928|beta-lactamase_A280Y|0.960411659 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGYSLIKHW +>1929|beta-lactamase_R273D|0.960411659 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNDQIAEIGASLIKHW +>1930|beta-lactamase_E61F|0.960411659 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPFERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1931|beta-lactamase_T198C|0.960247078 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLCLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1932|beta-lactamase_D36H|0.960205053 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEHQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1933|beta-lactamase_S233G|0.960174756 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKGGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1934|beta-lactamase_I283L|0.960086014 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLLKHW +>1935|beta-lactamase_T139N|0.959988575 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTNIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1936|beta-lactamase_P253I|0.959807867 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKISRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1937|beta-lactamase_H94G|0.959761542 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIGYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1938|beta-lactamase_E237I|0.959683356 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGIRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1939|beta-lactamase_A211T|0.959643872 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMETDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1940|beta-lactamase_L196L|0.95954666 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1941|beta-lactamase_V258I|0.959523172 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYTTGSQATMDERNRQIAEIGASLIKHW +>1942|beta-lactamase_K30S|0.959523172 +MSIQHFRVALIPFFAAFCLPVFAHPETLVSVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1943|beta-lactamase_P253H|0.959523172 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKHSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1944|beta-lactamase_V101C|0.959523172 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLCEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1945|beta-lactamase_H151C|0.959523172 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLCNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1946|beta-lactamase_E108T|0.959523172 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTTKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1947|beta-lactamase_K32E|0.959523172 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVEDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1948|beta-lactamase_W163A|0.959433552 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRAEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1949|beta-lactamase_A182E|0.959292328 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPEAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1950|beta-lactamase_Q204R|0.959292328 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQRLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1951|beta-lactamase_R92F|0.959272586 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRFIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1952|beta-lactamase_R273S|0.95918619 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNSQIAEIGASLIKHW +>1953|beta-lactamase_N173V|0.95918619 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPVDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1954|beta-lactamase_H5T|0.95918619 +MSIQTFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1955|beta-lactamase_K190L|0.959085526 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRLLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1956|beta-lactamase_I275L|0.958948309 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQLAEIGASLIKHW +>1957|beta-lactamase_H24I|0.958899345 +MSIQHFRVALIPFFAAFCLPVFAIPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1958|beta-lactamase_F149I|0.958858982 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAILHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1959|beta-lactamase_A266H|0.958825068 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQHTMDERNRQIAEIGASLIKHW +>1960|beta-lactamase_P172G|0.958805326 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIGNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1961|beta-lactamase_E175G|0.958743168 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDGRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1962|beta-lactamase_A40S|0.958698896 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGSRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1963|beta-lactamase_A16A|0.958580354 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1964|beta-lactamase_G90R|0.958522781 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLRRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1965|beta-lactamase_F70V|0.958437265 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTVKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1966|beta-lactamase_T262N|0.958437265 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTNGSQATMDERNRQIAEIGASLIKHW +>1967|beta-lactamase_A16I|0.958437265 +MSIQHFRVALIPFFAIFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1968|beta-lactamase_F14A|0.958437265 +MSIQHFRVALIPFAAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1969|beta-lactamase_H24F|0.958437265 +MSIQHFRVALIPFFAAFCLPVFAFPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1970|beta-lactamase_P25L|0.958343638 +MSIQHFRVALIPFFAAFCLPVFAHLETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1971|beta-lactamase_K32N|0.958126964 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVNDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1972|beta-lactamase_R91K|0.957894263 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGKRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1973|beta-lactamase_T139M|0.957798485 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTMIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1974|beta-lactamase_Y95W|0.957661562 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHWSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1975|beta-lactamase_E145Y|0.957450068 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKYLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1976|beta-lactamase_S201G|0.957329173 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAGRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1977|beta-lactamase_H285S|0.957329173 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKSW +>1978|beta-lactamase_E87D|0.957230659 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQDQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1979|beta-lactamase_P60F|0.957079857 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRFEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1980|beta-lactamase_I140L|0.956819889 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTLGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1981|beta-lactamase_F58S|0.956819889 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESSRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1982|beta-lactamase_I3C|0.956819889 +MSCQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1983|beta-lactamase_S221Y|0.956749717 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRYALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1984|beta-lactamase_E119A|0.956730854 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRALCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1985|beta-lactamase_F13C|0.956685799 +MSIQHFRVALIPCFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1986|beta-lactamase_L38I|0.956436875 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQIGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1987|beta-lactamase_C18G|0.956436875 +MSIQHFRVALIPFFAAFGLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1988|beta-lactamase_S201A|0.956388399 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAARQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1989|beta-lactamase_D99A|0.956361229 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNALVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1990|beta-lactamase_D83E|0.956287637 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVEAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1991|beta-lactamase_D207F|0.956265452 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIFWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1992|beta-lactamase_E237V|0.956244244 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGVRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1993|beta-lactamase_A183M|0.955969224 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAMMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1994|beta-lactamase_R118V|0.955969224 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVVELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1995|beta-lactamase_G226R|0.955592269 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPARWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1996|beta-lactamase_R81H|0.955486425 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSHVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1997|beta-lactamase_A34I|0.955334646 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDIEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1998|beta-lactamase_V106A|0.955334646 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPATEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>1999|beta-lactamase_G216T|0.955334646 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVATPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2000|beta-lactamase_K190C|0.955334646 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRCLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2001|beta-lactamase_E26Q|0.955334646 +MSIQHFRVALIPFFAAFCLPVFAHPQTLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2002|beta-lactamase_H151F|0.955334646 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLFNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2003|beta-lactamase_N50W|0.955334646 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLWSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2004|beta-lactamase_F6C|0.955334646 +MSIQHCRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2005|beta-lactamase_E26V|0.954994146 +MSIQHFRVALIPFFAAFCLPVFAHPVTLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2006|beta-lactamase_L219V|0.954923974 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLVRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2007|beta-lactamase_R81F|0.954923974 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSFVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2008|beta-lactamase_V8P|0.954923974 +MSIQHFRPALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2009|beta-lactamase_R189T|0.954893774 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLTKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2010|beta-lactamase_R41Q|0.954849013 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAQVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2011|beta-lactamase_V42M|0.954709451 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARMGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2012|beta-lactamase_R81Q|0.954636542 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSQVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2013|beta-lactamase_K53D|0.954636542 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGDILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2014|beta-lactamase_T126V|0.954365041 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIVMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2015|beta-lactamase_S57V|0.954260663 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEVFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2016|beta-lactamase_F17W|0.954260663 +MSIQHFRVALIPFFAAWCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2017|beta-lactamase_L10S|0.954260663 +MSIQHFRVASIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2018|beta-lactamase_G242A|0.954233688 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRAIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2019|beta-lactamase_R63K|0.954131069 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEKFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2020|beta-lactamase_F22A|0.954131069 +MSIQHFRVALIPFFAAFCLPVAAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2021|beta-lactamase_A245S|0.953884783 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIISALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2022|beta-lactamase_K213F|0.953659216 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADFVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2023|beta-lactamase_R92S|0.953637617 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRSIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2024|beta-lactamase_V82A|0.953589435 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRADAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2025|beta-lactamase_A133S|0.95350128 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTASNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2026|beta-lactamase_T158T|0.953491908 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2027|beta-lactamase_R189L|0.953478411 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLLKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2028|beta-lactamase_G85A|0.953421042 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAAQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2029|beta-lactamase_A183I|0.953320866 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAIMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2030|beta-lactamase_L223A|0.953062852 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAAPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2031|beta-lactamase_E270H|0.953007633 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDHRNRQIAEIGASLIKHW +>2032|beta-lactamase_V29S|0.953007633 +MSIQHFRVALIPFFAAFCLPVFAHPETLSKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2033|beta-lactamase_Q97N|0.953007633 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSNNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2034|beta-lactamase_A276V|0.952731538 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIVEIGASLIKHW +>2035|beta-lactamase_I229V|0.952572136 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFVADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2036|beta-lactamase_L135M|0.95254223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANMLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2037|beta-lactamase_G226E|0.952521413 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAEWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2038|beta-lactamase_T267L|0.952468344 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQALMDERNRQIAEIGASLIKHW +>2039|beta-lactamase_P60L|0.95246209 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRLEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2040|beta-lactamase_L205I|0.952445964 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQIIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2041|beta-lactamase_F6N|0.952299462 +MSIQHNRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2042|beta-lactamase_P25K|0.952193227 +MSIQHFRVALIPFFAAFCLPVFAHKETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2043|beta-lactamase_T198L|0.952119146 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLLLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2044|beta-lactamase_T261S|0.952049462 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYSTGSQATMDERNRQIAEIGASLIKHW +>2045|beta-lactamase_Q265C|0.952049462 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSCATMDERNRQIAEIGASLIKHW +>2046|beta-lactamase_E210S|0.951892015 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMSADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2047|beta-lactamase_D99S|0.951672508 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNSLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2048|beta-lactamase_P20H|0.951672508 +MSIQHFRVALIPFFAAFCLHVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2049|beta-lactamase_A77S|0.951526886 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGSVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2050|beta-lactamase_T198M|0.951526886 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLMLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2051|beta-lactamase_R273I|0.951526886 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNIQIAEIGASLIKHW +>2052|beta-lactamase_F22N|0.951526886 +MSIQHFRVALIPFFAAFCLPVNAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2053|beta-lactamase_R7N|0.951526886 +MSIQHFNVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2054|beta-lactamase_R202A|0.951431304 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASAQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2055|beta-lactamase_F149Y|0.951378821 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAYLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2056|beta-lactamase_R118I|0.951378821 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVIELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2057|beta-lactamase_L111Q|0.95097157 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHQTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2058|beta-lactamase_L111Y|0.95097157 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHYTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2059|beta-lactamase_K284W|0.95097157 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIWHW +>2060|beta-lactamase_V21S|0.95097157 +MSIQHFRVALIPFFAAFCLPSFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2061|beta-lactamase_P253L|0.950911073 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKLSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2062|beta-lactamase_R238T|0.95088791 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGETGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2063|beta-lactamase_S221L|0.950791644 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRLALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2064|beta-lactamase_E46K|0.950501671 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIKLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2065|beta-lactamase_L160F|0.950416253 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRFDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2066|beta-lactamase_A182D|0.950292914 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPDAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2067|beta-lactamase_R92Q|0.950292914 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRQIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2068|beta-lactamase_E61I|0.950292914 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPIERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2069|beta-lactamase_K284C|0.950292914 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLICHW +>2070|beta-lactamase_A77T|0.950098915 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGTVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2071|beta-lactamase_R81A|0.950007144 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSAVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2072|beta-lactamase_R91R|0.949938399 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2073|beta-lactamase_V117M|0.949749912 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTMRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2074|beta-lactamase_L28A|0.949749912 +MSIQHFRVALIPFFAAFCLPVFAHPETAVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2075|beta-lactamase_A280F|0.949749912 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGFSLIKHW +>2076|beta-lactamase_G39M|0.949749912 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLMARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2077|beta-lactamase_G39Y|0.949749912 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLYARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2078|beta-lactamase_A84Y|0.949749912 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDYGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2079|beta-lactamase_D269W|0.949749912 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMWERNRQIAEIGASLIKHW +>2080|beta-lactamase_P25W|0.949749912 +MSIQHFRVALIPFFAAFCLPVFAHWETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2081|beta-lactamase_Q4F|0.949749912 +MSIFHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2082|beta-lactamase_V21T|0.949502453 +MSIQHFRVALIPFFAAFCLPTFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2083|beta-lactamase_T147G|0.9491125 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELGAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2084|beta-lactamase_L160T|0.949051808 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRTDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2085|beta-lactamase_A34T|0.948935506 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDTEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2086|beta-lactamase_R41A|0.948935506 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAAVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2087|beta-lactamase_G90L|0.948861425 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLLRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2088|beta-lactamase_S221G|0.948857125 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRGALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2089|beta-lactamase_P172N|0.948468149 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAINNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2090|beta-lactamase_H151I|0.948353704 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLINMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2091|beta-lactamase_K53W|0.948353704 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGWILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2092|beta-lactamase_R7A|0.948353704 +MSIQHFAVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2093|beta-lactamase_I278L|0.948224013 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAELGASLIKHW +>2094|beta-lactamase_T262E|0.94816508 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTEGSQATMDERNRQIAEIGASLIKHW +>2095|beta-lactamase_A183Y|0.948050244 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAYMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2096|beta-lactamase_E210G|0.948050244 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMGADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2097|beta-lactamase_A276G|0.94799571 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIGEIGASLIKHW +>2098|beta-lactamase_T198T|0.947992129 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2099|beta-lactamase_L19P|0.947842953 +MSIQHFRVALIPFFAAFCPPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2100|beta-lactamase_A200L|0.94774913 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLLSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2101|beta-lactamase_R271S|0.947578098 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDESNRQIAEIGASLIKHW +>2102|beta-lactamase_F14L|0.947578098 +MSIQHFRVALIPFLAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2103|beta-lactamase_A40Q|0.947168305 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGQRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2104|beta-lactamase_G251Y|0.947084451 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDYKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2105|beta-lactamase_Q4T|0.947084451 +MSITHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2106|beta-lactamase_I45Y|0.946957594 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYYELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2107|beta-lactamase_K30I|0.946742778 +MSIQHFRVALIPFFAAFCLPVFAHPETLVIVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2108|beta-lactamase_T139C|0.946742778 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTCIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2109|beta-lactamase_K213T|0.946742778 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADTVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2110|beta-lactamase_A9N|0.946742778 +MSIQHFRVNLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2111|beta-lactamase_T139H|0.946300538 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTHIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2112|beta-lactamase_P217G|0.946300538 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGGLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2113|beta-lactamase_D207H|0.946300538 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIHWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2114|beta-lactamase_R202E|0.946026789 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASEQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2115|beta-lactamase_I54C|0.946026789 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKCLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2116|beta-lactamase_K32G|0.946026789 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVGDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2117|beta-lactamase_R91H|0.945925635 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGHRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2118|beta-lactamase_T262M|0.945840608 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTMGSQATMDERNRQIAEIGASLIKHW +>2119|beta-lactamase_A183N|0.945840608 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPANMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2120|beta-lactamase_V214T|0.945791155 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKTAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2121|beta-lactamase_P217V|0.945768188 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGVLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2122|beta-lactamase_T262I|0.945705835 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTIGSQATMDERNRQIAEIGASLIKHW +>2123|beta-lactamase_D99V|0.94561895 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNVLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2124|beta-lactamase_K144H|0.945523661 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPHELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2125|beta-lactamase_E108A|0.945459255 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTAKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2126|beta-lactamase_S80C|0.945406284 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLCRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2127|beta-lactamase_E62E|0.945371886 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2128|beta-lactamase_S122T|0.945361914 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCTAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2129|beta-lactamase_P249R|0.94527542 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGRDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2130|beta-lactamase_G234A|0.94526379 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSAAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2131|beta-lactamase_D250I|0.94525734 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPIGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2132|beta-lactamase_R176H|0.945115139 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEHDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2133|beta-lactamase_S254W|0.944863282 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPWRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2134|beta-lactamase_M127I|0.944863282 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITISDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2135|beta-lactamase_R59N|0.944863282 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFNPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2136|beta-lactamase_K109W|0.944863282 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEWHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2137|beta-lactamase_P60P|0.944754157 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2138|beta-lactamase_T147T|0.944664992 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2139|beta-lactamase_V157G|0.944616507 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHGTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2140|beta-lactamase_D99N|0.944519165 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNNLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2141|beta-lactamase_H5D|0.944295065 +MSIQDFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2142|beta-lactamase_S57C|0.944287441 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILECFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2143|beta-lactamase_P217R|0.944217856 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGRLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2144|beta-lactamase_G251C|0.944202903 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDCKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2145|beta-lactamase_D269P|0.943958376 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMPERNRQIAEIGASLIKHW +>2146|beta-lactamase_R92W|0.943958376 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRWIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2147|beta-lactamase_F149V|0.943897 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAVLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2148|beta-lactamase_L137I|0.94372157 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLITTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2149|beta-lactamase_P253F|0.943661659 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKFSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2150|beta-lactamase_A84F|0.943577316 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDFGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2151|beta-lactamase_R159R|0.943542146 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2152|beta-lactamase_L137Y|0.94333621 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLYTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2153|beta-lactamase_L150F|0.943316859 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFFHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2154|beta-lactamase_H285M|0.942983786 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKMW +>2155|beta-lactamase_P60N|0.942882242 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRNEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2156|beta-lactamase_K252D|0.942827219 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGDPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2157|beta-lactamase_H24Y|0.94276897 +MSIQHFRVALIPFFAAFCLPVFAYPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2158|beta-lactamase_L188T|0.942759783 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTTRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2159|beta-lactamase_T267I|0.9427332 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAIMDERNRQIAEIGASLIKHW +>2160|beta-lactamase_L136I|0.942683845 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLILTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2161|beta-lactamase_G194K|0.942642113 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTKELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2162|beta-lactamase_Q204Y|0.942642113 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQYLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2163|beta-lactamase_N98P|0.942642113 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQPDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2164|beta-lactamase_R41L|0.942528939 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGALVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2165|beta-lactamase_S57N|0.942506753 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILENFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2166|beta-lactamase_E56R|0.942504896 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILRSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2167|beta-lactamase_R238A|0.942457985 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEAGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2168|beta-lactamase_I206E|0.942335721 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLEDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2169|beta-lactamase_G236A|0.942291351 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAAERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2170|beta-lactamase_K213Y|0.942263986 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADYVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2171|beta-lactamase_E237F|0.942148466 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGFRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2172|beta-lactamase_K252W|0.942148466 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGWPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2173|beta-lactamase_F14C|0.942059431 +MSIQHFRVALIPFCAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2174|beta-lactamase_N272D|0.941931304 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERDRQIAEIGASLIKHW +>2175|beta-lactamase_H151D|0.941931304 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLDNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2176|beta-lactamase_A222Y|0.941862695 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSYLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2177|beta-lactamase_A276N|0.941809138 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQINEIGASLIKHW +>2178|beta-lactamase_R92N|0.941809138 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRNIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2179|beta-lactamase_H94P|0.941605561 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIPYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2180|beta-lactamase_M184Y|0.94137286 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAYATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2181|beta-lactamase_T126M|0.94137286 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIMMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2182|beta-lactamase_G263D|0.94137286 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTDSQATMDERNRQIAEIGASLIKHW +>2183|beta-lactamase_L111H|0.94137286 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHHTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2184|beta-lactamase_R63T|0.94121854 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEETFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2185|beta-lactamase_L47T|0.941062559 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIETDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2186|beta-lactamase_E145W|0.941062559 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKWLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2187|beta-lactamase_F58A|0.94092241 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESARPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2188|beta-lactamase_V78I|0.940895534 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAILSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2189|beta-lactamase_R41T|0.94084266 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGATVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2190|beta-lactamase_V72I|0.939976652 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKILLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2191|beta-lactamase_R189E|0.939719419 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLEKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2192|beta-lactamase_Y103F|0.93955171 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEFSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2193|beta-lactamase_E145L|0.939013106 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKLLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2194|beta-lactamase_K30Q|0.938965608 +MSIQHFRVALIPFFAAFCLPVFAHPETLVQVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2195|beta-lactamase_L111F|0.938965608 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHFTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2196|beta-lactamase_A9V|0.938932867 +MSIQHFRVVLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2197|beta-lactamase_N152I|0.938890745 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHIMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2198|beta-lactamase_V82T|0.938784803 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRTDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2199|beta-lactamase_T261A|0.938754994 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYATGSQATMDERNRQIAEIGASLIKHW +>2200|beta-lactamase_A77D|0.938754994 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGDVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2201|beta-lactamase_G194R|0.938580444 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTRELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2202|beta-lactamase_A245G|0.938473036 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIGALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2203|beta-lactamase_A182N|0.938433552 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPNAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2204|beta-lactamase_V101E|0.938433552 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLEEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2205|beta-lactamase_I54R|0.938433552 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKRLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2206|beta-lactamase_P25D|0.938433552 +MSIQHFRVALIPFFAAFCLPVFAHDETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2207|beta-lactamase_R92A|0.938337676 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRAIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2208|beta-lactamase_A170N|0.938308063 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNENIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2209|beta-lactamase_S221P|0.938255581 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRPALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2210|beta-lactamase_M127R|0.938234177 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITRSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2211|beta-lactamase_M67L|0.938199677 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMLSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2212|beta-lactamase_R59K|0.938199677 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFKPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2213|beta-lactamase_S57D|0.93790042 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEDFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2214|beta-lactamase_R41I|0.937677101 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAIVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2215|beta-lactamase_K32K|0.937624898 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2216|beta-lactamase_T267V|0.937513497 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAVMDERNRQIAEIGASLIKHW +>2217|beta-lactamase_L10F|0.937476554 +MSIQHFRVAFIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2218|beta-lactamase_T262K|0.936718931 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTKGSQATMDERNRQIAEIGASLIKHW +>2219|beta-lactamase_L49A|0.936718931 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDANSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2220|beta-lactamase_R162S|0.936718931 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2221|beta-lactamase_A148W|0.936718931 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTWFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2222|beta-lactamase_L100V|0.936718931 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDVVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2223|beta-lactamase_G226A|0.936718931 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAAWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2224|beta-lactamase_G39T|0.936718931 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLTARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2225|beta-lactamase_S51K|0.936718931 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNKGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2226|beta-lactamase_R159T|0.936718931 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTTLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2227|beta-lactamase_Q203Y|0.936718931 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRYQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2228|beta-lactamase_F17H|0.936718931 +MSIQHFRVALIPFFAAHCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2229|beta-lactamase_F6Q|0.936718931 +MSIQHQRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2230|beta-lactamase_L73P|0.936396315 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVPLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2231|beta-lactamase_G226C|0.936386444 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPACWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2232|beta-lactamase_G251L|0.936228997 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDLKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2233|beta-lactamase_S57F|0.936067348 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEFFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2234|beta-lactamase_R41V|0.93586162 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAVVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2235|beta-lactamase_T193D|0.93570085 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLDGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2236|beta-lactamase_I140V|0.935650811 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTVGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2237|beta-lactamase_H5L|0.935571843 +MSIQLFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2238|beta-lactamase_A77R|0.935465901 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGRVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2239|beta-lactamase_T147Q|0.935302492 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELQAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2240|beta-lactamase_G216S|0.935203685 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVASPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2241|beta-lactamase_M180L|0.935144556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTLPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2242|beta-lactamase_V257L|0.934957985 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRILVIYTTGSQATMDERNRQIAEIGASLIKHW +>2243|beta-lactamase_S2R|0.934532457 +MRIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2244|beta-lactamase_K213E|0.934526202 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADEVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2245|beta-lactamase_E102G|0.934487598 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVGYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2246|beta-lactamase_P165V|0.934391918 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEVELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2247|beta-lactamase_F22K|0.934391918 +MSIQHFRVALIPFFAAFCLPVKAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2248|beta-lactamase_R238V|0.934354388 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEVGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2249|beta-lactamase_A170H|0.934260174 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEHIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2250|beta-lactamase_P249Q|0.934147 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGQDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2251|beta-lactamase_T179S|0.934112695 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTSMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2252|beta-lactamase_T107C|0.934004115 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVCEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2253|beta-lactamase_L219F|0.933946355 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLFRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2254|beta-lactamase_S221D|0.933946355 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRDALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2255|beta-lactamase_L197M|0.93375734 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELMTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2256|beta-lactamase_A215S|0.933461112 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVSGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2257|beta-lactamase_P172W|0.933461112 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIWNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2258|beta-lactamase_Q265N|0.933394654 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSNATMDERNRQIAEIGASLIKHW +>2259|beta-lactamase_W163G|0.933330835 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRGEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2260|beta-lactamase_S201N|0.933099208 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLANRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2261|beta-lactamase_E210D|0.933099208 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMDADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2262|beta-lactamase_E87V|0.933067934 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQVQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2263|beta-lactamase_V42V|0.932761764 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2264|beta-lactamase_D99H|0.932646706 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNHLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2265|beta-lactamase_E26D|0.932646706 +MSIQHFRVALIPFFAAFCLPVFAHPDTLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2266|beta-lactamase_K32Y|0.932646706 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVYDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2267|beta-lactamase_R41S|0.932564709 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGASVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2268|beta-lactamase_E108L|0.932158043 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTLKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2269|beta-lactamase_F17L|0.932065002 +MSIQHFRVALIPFFAALCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2270|beta-lactamase_R81L|0.931965119 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSLVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2271|beta-lactamase_P25I|0.931928079 +MSIQHFRVALIPFFAAFCLPVFAHIETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2272|beta-lactamase_L282T|0.93179438 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASTIKHW +>2273|beta-lactamase_H5P|0.931782946 +MSIQPFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2274|beta-lactamase_M268V|0.931778254 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATVDERNRQIAEIGASLIKHW +>2275|beta-lactamase_L28T|0.931707007 +MSIQHFRVALIPFFAAFCLPVFAHPETTVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2276|beta-lactamase_A16P|0.931707007 +MSIQHFRVALIPFFAPFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2277|beta-lactamase_A215G|0.931653841 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVGGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2278|beta-lactamase_I206G|0.931400127 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLGDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2279|beta-lactamase_L74M|0.931289298 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLMCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2280|beta-lactamase_E145P|0.931053274 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKPLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2281|beta-lactamase_R238P|0.930428079 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEPGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2282|beta-lactamase_M268A|0.930350381 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATADERNRQIAEIGASLIKHW +>2283|beta-lactamase_M184F|0.930203391 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAFATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2284|beta-lactamase_Q274G|0.930203391 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRGIAEIGASLIKHW +>2285|beta-lactamase_M153Q|0.930203391 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNQGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2286|beta-lactamase_K32C|0.930203391 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVCDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2287|beta-lactamase_S2P|0.930203391 +MPIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2288|beta-lactamase_R59H|0.930020729 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFHPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2289|beta-lactamase_L219M|0.929879408 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLMRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2290|beta-lactamase_N173I|0.929808552 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPIDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2291|beta-lactamase_T126Q|0.929675147 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIQMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2292|beta-lactamase_G90C|0.929656675 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLCRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2293|beta-lactamase_D83Q|0.92942153 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVQAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2294|beta-lactamase_G154Q|0.929201046 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMQDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2295|beta-lactamase_F6I|0.929201046 +MSIQHIRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2296|beta-lactamase_D113V|0.928807183 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTVGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2297|beta-lactamase_S221F|0.928747762 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRFALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2298|beta-lactamase_A34F|0.928574482 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDFEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2299|beta-lactamase_T27I|0.928574482 +MSIQHFRVALIPFFAAFCLPVFAHPEILVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2300|beta-lactamase_A211F|0.928574482 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEFDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2301|beta-lactamase_R81S|0.928574482 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSSVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2302|beta-lactamase_F14Y|0.928574482 +MSIQHFRVALIPFYAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2303|beta-lactamase_T107T|0.928523846 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2304|beta-lactamase_G154E|0.928354388 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMEDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2305|beta-lactamase_L55R|0.928354388 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIRESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2306|beta-lactamase_L38T|0.928145827 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQTGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2307|beta-lactamase_L10Y|0.928145827 +MSIQHFRVAYIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2308|beta-lactamase_A246S|0.928065491 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIASLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2309|beta-lactamase_R7S|0.928065491 +MSIQHFSVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2310|beta-lactamase_K190I|0.927834158 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRILLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2311|beta-lactamase_V106C|0.927793501 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPCTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2312|beta-lactamase_I244L|0.927595006 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGILAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2313|beta-lactamase_G279C|0.927411073 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEICASLIKHW +>2314|beta-lactamase_E46L|0.927411073 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYILLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2315|beta-lactamase_A40M|0.927411073 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGMRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2316|beta-lactamase_G194F|0.927411073 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTFELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2317|beta-lactamase_E119H|0.927411073 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRHLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2318|beta-lactamase_K109C|0.927411073 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTECHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2319|beta-lactamase_P253S|0.927354486 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKSSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2320|beta-lactamase_F6R|0.927137226 +MSIQHRRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2321|beta-lactamase_I278V|0.927093735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEVGASLIKHW +>2322|beta-lactamase_H285L|0.926480268 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKLW +>2323|beta-lactamase_I125C|0.92645476 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAACTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2324|beta-lactamase_K144W|0.926389474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPWELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2325|beta-lactamase_V42W|0.926179154 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARWGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2326|beta-lactamase_M268W|0.926179154 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATWDERNRQIAEIGASLIKHW +>2327|beta-lactamase_I54Y|0.926179154 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKYLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2328|beta-lactamase_F58R|0.926112305 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESRRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2329|beta-lactamase_A77E|0.925859763 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGEVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2330|beta-lactamase_R162D|0.925859763 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDDWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2331|beta-lactamase_R159Q|0.925859763 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTQLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2332|beta-lactamase_R7F|0.925859763 +MSIQHFFVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2333|beta-lactamase_T187C|0.925665764 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATCLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2334|beta-lactamase_L191V|0.925556011 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKVLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2335|beta-lactamase_M184V|0.925520338 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAVATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2336|beta-lactamase_A170I|0.925485252 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEIIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2337|beta-lactamase_I278M|0.925371687 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEMGASLIKHW +>2338|beta-lactamase_L28K|0.925316761 +MSIQHFRVALIPFFAAFCLPVFAHPETKVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2339|beta-lactamase_K32T|0.925316761 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVTDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2340|beta-lactamase_F17C|0.925316761 +MSIQHFRVALIPFFAACCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2341|beta-lactamase_P25C|0.925159118 +MSIQHFRVALIPFFAAFCLPVFAHCETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2342|beta-lactamase_C75G|0.925098915 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLGGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2343|beta-lactamase_T126I|0.92508406 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIIMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2344|beta-lactamase_I283T|0.924913321 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLTKHW +>2345|beta-lactamase_V258A|0.924872566 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVAIYTTGSQATMDERNRQIAEIGASLIKHW +>2346|beta-lactamase_E46F|0.924872566 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIFLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2347|beta-lactamase_P165C|0.924872566 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWECELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2348|beta-lactamase_R189V|0.924662637 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLVKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2349|beta-lactamase_P253G|0.924533434 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKGSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2350|beta-lactamase_D99T|0.924502355 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNTLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2351|beta-lactamase_M127C|0.924435604 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITCSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2352|beta-lactamase_P172F|0.924339435 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIFNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2353|beta-lactamase_L188C|0.924293989 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTCRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2354|beta-lactamase_A123S|0.924189122 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSSAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2355|beta-lactamase_S264A|0.924189122 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGAQATMDERNRQIAEIGASLIKHW +>2356|beta-lactamase_I283C|0.924189122 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLCKHW +>2357|beta-lactamase_K190W|0.924189122 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRWLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2358|beta-lactamase_W163H|0.924189122 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRHEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2359|beta-lactamase_T198R|0.923751183 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLRLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2360|beta-lactamase_I244C|0.923715217 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGICAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2361|beta-lactamase_H5E|0.923687852 +MSIQEFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2362|beta-lactamase_H285A|0.92363449 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKAW +>2363|beta-lactamase_L150A|0.923437265 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFAHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2364|beta-lactamase_A183R|0.923358982 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPARMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2365|beta-lactamase_D250P|0.923304642 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPPGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2366|beta-lactamase_H285V|0.922936093 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKVW +>2367|beta-lactamase_A222D|0.922852043 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSDLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2368|beta-lactamase_A34Q|0.922757144 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDQEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2369|beta-lactamase_M66F|0.92255474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPFMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2370|beta-lactamase_A9R|0.922438341 +MSIQHFRVRLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2371|beta-lactamase_L38Y|0.92228578 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQYGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2372|beta-lactamase_Q4L|0.922240041 +MSILHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2373|beta-lactamase_G234S|0.92212413 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSSAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2374|beta-lactamase_V29R|0.921910975 +MSIQHFRVALIPFFAAFCLPVFAHPETLRKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2375|beta-lactamase_T147E|0.921826339 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELEAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2376|beta-lactamase_E46V|0.921750889 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIVLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2377|beta-lactamase_S57L|0.921636738 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILELFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2378|beta-lactamase_P253V|0.921033434 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKVSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2379|beta-lactamase_L150T|0.920430131 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFTHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2380|beta-lactamase_V72T|0.920430131 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKTLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2381|beta-lactamase_Y44M|0.920430131 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGMIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2382|beta-lactamase_A266D|0.920430131 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQDTMDERNRQIAEIGASLIKHW +>2383|beta-lactamase_P60Y|0.920430131 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRYEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2384|beta-lactamase_R202C|0.920430131 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASCQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2385|beta-lactamase_G39I|0.920430131 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLIARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2386|beta-lactamase_D99I|0.920430131 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNILVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2387|beta-lactamase_H24W|0.920430131 +MSIQHFRVALIPFFAAFCLPVFAWPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2388|beta-lactamase_H5C|0.920430131 +MSIQCFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2389|beta-lactamase_R7I|0.920430131 +MSIQHFIVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2390|beta-lactamase_S2W|0.920430131 +MWIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2391|beta-lactamase_P217L|0.919952609 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGLLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2392|beta-lactamase_G194L|0.919601847 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTLELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2393|beta-lactamase_G226Q|0.919177101 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAQWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2394|beta-lactamase_S51G|0.918853802 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNGGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2395|beta-lactamase_V82S|0.91884354 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRSDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2396|beta-lactamase_D99L|0.918705444 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNLLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2397|beta-lactamase_I140Y|0.918475479 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTYGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2398|beta-lactamase_T147C|0.918475479 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELCAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2399|beta-lactamase_H285K|0.918394068 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKKW +>2400|beta-lactamase_H110Q|0.918394068 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKQLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2401|beta-lactamase_V78M|0.918305522 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAMLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2402|beta-lactamase_R202V|0.918103118 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASVQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2403|beta-lactamase_S221W|0.9178582 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRWALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2404|beta-lactamase_R176C|0.9178582 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDECDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2405|beta-lactamase_D113C|0.9178582 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTCGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2406|beta-lactamase_A276E|0.91755562 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIEEIGASLIKHW +>2407|beta-lactamase_L100F|0.91755562 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDFVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2408|beta-lactamase_F17G|0.91755562 +MSIQHFRVALIPFFAAGCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2409|beta-lactamase_T147D|0.917277473 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELDAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2410|beta-lactamase_L137F|0.91717241 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLFTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2411|beta-lactamase_L111W|0.91717241 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHWTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2412|beta-lactamase_P253R|0.917145045 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKRSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2413|beta-lactamase_T187A|0.917076534 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATALRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2414|beta-lactamase_L282A|0.916939709 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASAIKHW +>2415|beta-lactamase_R176S|0.916881167 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDESDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2416|beta-lactamase_E62A|0.91667114 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEARFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2417|beta-lactamase_A200F|0.91667114 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLFSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2418|beta-lactamase_P25Y|0.91667114 +MSIQHFRVALIPFFAAFCLPVFAHYETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2419|beta-lactamase_R7Y|0.916357907 +MSIQHFYVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2420|beta-lactamase_M268H|0.916086503 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATHDERNRQIAEIGASLIKHW +>2421|beta-lactamase_F70C|0.915987695 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTCKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2422|beta-lactamase_L73T|0.915987695 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVTLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2423|beta-lactamase_W163Q|0.915987695 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRQEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2424|beta-lactamase_V82H|0.91589612 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRHDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2425|beta-lactamase_M127S|0.915662735 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITSSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2426|beta-lactamase_R63Q|0.915639279 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEQFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2427|beta-lactamase_R63L|0.915597156 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEELFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2428|beta-lactamase_F228A|0.915514572 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWAIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2429|beta-lactamase_H285G|0.915418208 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKGW +>2430|beta-lactamase_L47C|0.91537501 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIECDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2431|beta-lactamase_P25N|0.91537501 +MSIQHFRVALIPFFAAFCLPVFAHNETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2432|beta-lactamase_S240E|0.915286269 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGERGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2433|beta-lactamase_L111K|0.914321843 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHKTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2434|beta-lactamase_R176F|0.914321843 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEFDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2435|beta-lactamase_G216W|0.913914591 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAWPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2436|beta-lactamase_P165L|0.913723036 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWELELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2437|beta-lactamase_V31A|0.913689904 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKAKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2438|beta-lactamase_F13S|0.913588849 +MSIQHFRVALIPSFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2439|beta-lactamase_E46H|0.913449189 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIHLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2440|beta-lactamase_T116L|0.913449189 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMLVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2441|beta-lactamase_G216C|0.912714435 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVACPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2442|beta-lactamase_E62Y|0.912714435 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEYRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2443|beta-lactamase_L146I|0.912518481 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEITAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2444|beta-lactamase_V106Y|0.912433845 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPYTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2445|beta-lactamase_H94C|0.91228578 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRICYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2446|beta-lactamase_F149T|0.912160487 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTATLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2447|beta-lactamase_S254F|0.911861132 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPFRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2448|beta-lactamase_Q4V|0.911545358 +MSIVHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2449|beta-lactamase_H24C|0.911380776 +MSIQHFRVALIPFFAAFCLPVFACPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2450|beta-lactamase_M127K|0.911185115 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITKSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2451|beta-lactamase_H5R|0.911122273 +MSIQRFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2452|beta-lactamase_A170R|0.911084158 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNERIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2453|beta-lactamase_A123C|0.910656871 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSCAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2454|beta-lactamase_R81M|0.910656871 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSMVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2455|beta-lactamase_I54W|0.910656871 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKWLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2456|beta-lactamase_E195C|0.910656871 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGCLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2457|beta-lactamase_F6W|0.910656871 +MSIQHWRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2458|beta-lactamase_H5I|0.910656871 +MSIQIFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2459|beta-lactamase_F149A|0.910304642 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAALHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2460|beta-lactamase_F149L|0.910174267 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTALLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2461|beta-lactamase_Q204D|0.910064513 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQDLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2462|beta-lactamase_E119S|0.910064513 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRSLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2463|beta-lactamase_L38F|0.910016038 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQFGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2464|beta-lactamase_L47A|0.909703391 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEADLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2465|beta-lactamase_G85M|0.909663028 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAMQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2466|beta-lactamase_I3M|0.909570964 +MSMQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2467|beta-lactamase_S2C|0.909460135 +MCIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2468|beta-lactamase_L137V|0.909199971 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLVTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2469|beta-lactamase_L49T|0.909153254 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDTNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2470|beta-lactamase_I11L|0.909107418 +MSIQHFRVALLPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2471|beta-lactamase_R159S|0.908993364 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTSLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2472|beta-lactamase_T27L|0.90879526 +MSIQHFRVALIPFFAAFCLPVFAHPELLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2473|beta-lactamase_I171P|0.90879526 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAPPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2474|beta-lactamase_E270G|0.908634783 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDGRNRQIAEIGASLIKHW +>2475|beta-lactamase_I206H|0.908213556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLHDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2476|beta-lactamase_P253N|0.908213556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKNSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2477|beta-lactamase_R176N|0.908213556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDENDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2478|beta-lactamase_E108F|0.908213556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTFKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2479|beta-lactamase_R92P|0.908213556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRPIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2480|beta-lactamase_F6H|0.908213556 +MSIQHHRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2481|beta-lactamase_P25F|0.908213556 +MSIQHFRVALIPFFAAFCLPVFAHFETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2482|beta-lactamase_P25R|0.907864552 +MSIQHFRVALIPFFAAFCLPVFAHRETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2483|beta-lactamase_L73F|0.907761054 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVFLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2484|beta-lactamase_R91T|0.907761054 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGTRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2485|beta-lactamase_M127A|0.907620514 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITASDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2486|beta-lactamase_F58V|0.90739915 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESVRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2487|beta-lactamase_F58T|0.907102922 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESTRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2488|beta-lactamase_R41F|0.907102922 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAFVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2489|beta-lactamase_A170P|0.906828196 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEPIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2490|beta-lactamase_G85Y|0.906747566 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAYQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2491|beta-lactamase_A23S|0.906747566 +MSIQHFRVALIPFFAAFCLPVFSHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2492|beta-lactamase_V101L|0.906468344 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLLEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2493|beta-lactamase_E62H|0.906468344 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEHRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2494|beta-lactamase_R7V|0.906388106 +MSIQHFVVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2495|beta-lactamase_I244M|0.90619352 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIMAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2496|beta-lactamase_P249A|0.905996296 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGADGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2497|beta-lactamase_R81Y|0.90577024 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSYVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2498|beta-lactamase_L19R|0.905622176 +MSIQHFRVALIPFFAAFCRPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2499|beta-lactamase_T187M|0.905527668 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATMLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2500|beta-lactamase_P253Q|0.905347938 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKQSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2501|beta-lactamase_H110C|0.905072136 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKCLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2502|beta-lactamase_R92E|0.905072136 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGREIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2503|beta-lactamase_A15H|0.905072136 +MSIQHFRVALIPFFHAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2504|beta-lactamase_R162G|0.904998642 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDGWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2505|beta-lactamase_P12K|0.904935897 +MSIQHFRVALIKFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2506|beta-lactamase_Q4P|0.904935897 +MSIPHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2507|beta-lactamase_S2A|0.904834548 +MAIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2508|beta-lactamase_A40T|0.904642602 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGTRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2509|beta-lactamase_T262A|0.904445866 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTAGSQATMDERNRQIAEIGASLIKHW +>2510|beta-lactamase_T131C|0.904141331 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNCAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2511|beta-lactamase_E56H|0.904141331 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILHSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2512|beta-lactamase_V101R|0.904141331 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLREYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2513|beta-lactamase_F58C|0.904141331 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESCRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2514|beta-lactamase_V214K|0.904141331 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKKAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2515|beta-lactamase_W227F|0.904141331 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGFFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2516|beta-lactamase_H110N|0.904141331 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKNLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2517|beta-lactamase_S51A|0.904141331 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNAGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2518|beta-lactamase_E270N|0.904141331 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDNRNRQIAEIGASLIKHW +>2519|beta-lactamase_E277H|0.904141331 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAHIGASLIKHW +>2520|beta-lactamase_E195V|0.904141331 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGVLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2521|beta-lactamase_V42C|0.90377112 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARCGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2522|beta-lactamase_S104A|0.903210624 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYAPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2523|beta-lactamase_R176A|0.903210624 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEADTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2524|beta-lactamase_N50C|0.903183161 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLCSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2525|beta-lactamase_I283A|0.90309051 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLAKHW +>2526|beta-lactamase_G85L|0.903017993 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDALQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2527|beta-lactamase_E87F|0.902977922 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQFQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2528|beta-lactamase_R189D|0.902876183 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLDKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2529|beta-lactamase_G216D|0.90272499 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVADPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2530|beta-lactamase_A170T|0.902716097 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNETIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2531|beta-lactamase_H5V|0.902660584 +MSIQVFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2532|beta-lactamase_V106H|0.902590022 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPHTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2533|beta-lactamase_L28R|0.90251252 +MSIQHFRVALIPFFAAFCLPVFAHPETRVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2534|beta-lactamase_F17N|0.90242671 +MSIQHFRVALIPFFAANCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2535|beta-lactamase_K32F|0.902105268 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVFDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2536|beta-lactamase_L111R|0.901993364 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHRTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2537|beta-lactamase_D99K|0.901940197 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNKLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2538|beta-lactamase_R63H|0.901635369 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEHFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2539|beta-lactamase_Y260I|0.901426613 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIITTGSQATMDERNRQIAEIGASLIKHW +>2540|beta-lactamase_E277F|0.901426613 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAFIGASLIKHW +>2541|beta-lactamase_R271C|0.901308552 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDECNRQIAEIGASLIKHW +>2542|beta-lactamase_P249S|0.901284705 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGSDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2543|beta-lactamase_M268Q|0.90115257 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATQDERNRQIAEIGASLIKHW +>2544|beta-lactamase_M268T|0.901110936 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATTDERNRQIAEIGASLIKHW +>2545|beta-lactamase_A16Y|0.90088361 +MSIQHFRVALIPFFAYFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2546|beta-lactamase_P249M|0.9005781959999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGMDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2547|beta-lactamase_P165I|0.900439416 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEIELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2548|beta-lactamase_V214A|0.900382437 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKAAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2549|beta-lactamase_H110G|0.9003087470000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKGLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2550|beta-lactamase_P249N|0.900232027 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGNDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2551|beta-lactamase_P165N|0.899854877 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWENELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2552|beta-lactamase_A34L|0.8997241109999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDLEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2553|beta-lactamase_Q203F|0.899487402 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRFQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2554|beta-lactamase_E210L|0.899487402 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMLADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2555|beta-lactamase_E108Y|0.899487402 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTYKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2556|beta-lactamase_F6S|0.899487402 +MSIQHSRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2557|beta-lactamase_P181C|0.899240334 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMCAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2558|beta-lactamase_A185S|0.899224013 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMSTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2559|beta-lactamase_D48S|0.899224013 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELSLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2560|beta-lactamase_L167T|0.899129408 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPETNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2561|beta-lactamase_P253T|0.898711796 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKTSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2562|beta-lactamase_A9Q|0.898711796 +MSIQHFRVQLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2563|beta-lactamase_L89F|0.8985657840000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQFGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2564|beta-lactamase_F70W|0.8982181490000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTWKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2565|beta-lactamase_A211V|0.8981655690000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEVDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2566|beta-lactamase_A170L|0.898131949 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNELIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2567|beta-lactamase_A183C|0.897876476 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPACMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2568|beta-lactamase_W163D|0.897784803 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRDEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2569|beta-lactamase_L28S|0.8976258890000001 +MSIQHFRVALIPFFAAFCLPVFAHPETSVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2570|beta-lactamase_G154D|0.8976258890000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMDDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2571|beta-lactamase_T187V|0.897578978 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATVLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2572|beta-lactamase_A132S|0.897492875 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTSANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2573|beta-lactamase_A183K|0.897379994 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAKMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2574|beta-lactamase_A222F|0.897339435 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSFLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2575|beta-lactamase_L55H|0.8972829459999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIHESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2576|beta-lactamase_M268Y|0.8972829459999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATYDERNRQIAEIGASLIKHW +>2577|beta-lactamase_L55K|0.8971604870000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIKESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2578|beta-lactamase_G216L|0.896901886 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVALPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2579|beta-lactamase_G251F|0.8967374020000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDFKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2580|beta-lactamase_I229M|0.896565197 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFMADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2581|beta-lactamase_L38S|0.896476065 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQSGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2582|beta-lactamase_T186P|0.896351065 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAPTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2583|beta-lactamase_S281D|0.89599698 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGADLIKHW +>2584|beta-lactamase_A211W|0.89599698 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEWDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2585|beta-lactamase_H110W|0.89599698 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKWLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2586|beta-lactamase_E277Y|0.89599698 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAYIGASLIKHW +>2587|beta-lactamase_Q4W|0.89599698 +MSIWHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2588|beta-lactamase_E62V|0.895517895 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEVRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2589|beta-lactamase_T187G|0.895484373 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATGLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2590|beta-lactamase_A276L|0.8952565579999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQILEIGASLIKHW +>2591|beta-lactamase_R238E|0.895164885 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEEGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2592|beta-lactamase_T126L|0.895154427 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAILMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2593|beta-lactamase_T147K|0.895092074 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELKAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2594|beta-lactamase_D161N|0.895019654 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLNRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2595|beta-lactamase_H110A|0.895019654 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKALTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2596|beta-lactamase_A235S|0.894970397 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGSGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2597|beta-lactamase_E87T|0.8949646309999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQTQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2598|beta-lactamase_G263S|0.894934627 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTSSQATMDERNRQIAEIGASLIKHW +>2599|beta-lactamase_L192C|0.8948334729999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLCTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2600|beta-lactamase_E56M|0.8948334729999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILMSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2601|beta-lactamase_N272T|0.8947110140000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERTRQIAEIGASLIKHW +>2602|beta-lactamase_L28Q|0.894664298 +MSIQHFRVALIPFFAAFCLPVFAHPETQVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2603|beta-lactamase_G216H|0.8945597240000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAHPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2604|beta-lactamase_T107V|0.894251769 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVVEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2605|beta-lactamase_L197I|0.894117484 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELITLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2606|beta-lactamase_A40C|0.894117484 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGCRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2607|beta-lactamase_I206N|0.894117484 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLNDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2608|beta-lactamase_L55T|0.894117484 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKITESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2609|beta-lactamase_V106S|0.893970885 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPSTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2610|beta-lactamase_L73C|0.8939611120000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVCLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2611|beta-lactamase_M209L|0.8939024729999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWLEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2612|beta-lactamase_G251P|0.89377542 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDPKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2613|beta-lactamase_R7W|0.893632731 +MSIQHFWVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2614|beta-lactamase_I11G|0.893397195 +MSIQHFRVALGPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2615|beta-lactamase_A124V|0.893371785 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAVITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2616|beta-lactamase_T262V|0.8932818709999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTVGSQATMDERNRQIAEIGASLIKHW +>2617|beta-lactamase_K190F|0.8932818709999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRFLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2618|beta-lactamase_L136V|0.8931137709999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLVLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2619|beta-lactamase_T262R|0.893098133 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTRGSQATMDERNRQIAEIGASLIKHW +>2620|beta-lactamase_L73S|0.892851847 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVSLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2621|beta-lactamase_G52D|0.892844029 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSDKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2622|beta-lactamase_G216Y|0.892809822 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAYPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2623|beta-lactamase_V78V|0.892681318 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2624|beta-lactamase_A183F|0.8925068509999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAFMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2625|beta-lactamase_L10G|0.8925068509999999 +MSIQHFRVAGIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2626|beta-lactamase_E35Q|0.8921393759999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAQDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2627|beta-lactamase_L197L|0.891867759 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2628|beta-lactamase_P165P|0.891729387 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2629|beta-lactamase_L282F|0.891110252 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASFIKHW +>2630|beta-lactamase_T262W|0.891110252 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTWGSQATMDERNRQIAEIGASLIKHW +>2631|beta-lactamase_A183W|0.891110252 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAWMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2632|beta-lactamase_A266Y|0.891110252 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQYTMDERNRQIAEIGASLIKHW +>2633|beta-lactamase_T139K|0.891110252 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTKIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2634|beta-lactamase_S122C|0.891110252 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCCAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2635|beta-lactamase_L55C|0.891110252 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKICESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2636|beta-lactamase_E108W|0.891110252 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTWKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2637|beta-lactamase_C18V|0.891110252 +MSIQHFRVALIPFFAAFVLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2638|beta-lactamase_T187I|0.890966585 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATILRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2639|beta-lactamase_P143H|0.8905668590000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGHKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2640|beta-lactamase_E56V|0.890463262 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILVSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2641|beta-lactamase_S201T|0.89030689 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLATRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2642|beta-lactamase_V72A|0.8902482509999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKALLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2643|beta-lactamase_S240C|0.890071355 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGCRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2644|beta-lactamase_G39W|0.889888595 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLWARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2645|beta-lactamase_Q97C|0.889784998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSCNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2646|beta-lactamase_I243C|0.8896628320000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGCIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2647|beta-lactamase_R63I|0.8896628320000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEIFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2648|beta-lactamase_Y95V|0.889607125 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHVSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2649|beta-lactamase_D161E|0.8893842940000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLERWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2650|beta-lactamase_L49C|0.889333473 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDCNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2651|beta-lactamase_H110S|0.889333473 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKSLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2652|beta-lactamase_M127N|0.8891556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITNSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2653|beta-lactamase_M67Q|0.888967953 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMQSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2654|beta-lactamase_E56L|0.888810604 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILLSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2655|beta-lactamase_P20S|0.888810604 +MSIQHFRVALIPFFAAFCLSVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2656|beta-lactamase_E56C|0.8885604090000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILCSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2657|beta-lactamase_K53C|0.8885604090000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGCILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2658|beta-lactamase_W208M|0.8885037240000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDMMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2659|beta-lactamase_T187L|0.8884450840000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATLLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2660|beta-lactamase_L55Q|0.888377649 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIQESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2661|beta-lactamase_V8G|0.8880815190000001 +MSIQHFRGALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2662|beta-lactamase_S233A|0.888056108 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKAGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2663|beta-lactamase_L79L|0.8879909429999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2664|beta-lactamase_V31M|0.8878528240000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKMKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2665|beta-lactamase_M153G|0.8878528240000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNGGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2666|beta-lactamase_G194M|0.8878528240000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTMELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2667|beta-lactamase_G154N|0.8878528240000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMNDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2668|beta-lactamase_H156M|0.8878528240000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDMVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2669|beta-lactamase_L19E|0.8878528240000001 +MSIQHFRVALIPFFAAFCEPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2670|beta-lactamase_R81R|0.887772883 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2671|beta-lactamase_R63S|0.8877609559999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEESFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2672|beta-lactamase_Y44I|0.886847156 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGIIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2673|beta-lactamase_T107L|0.886767015 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVLEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2674|beta-lactamase_L167A|0.886745514 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEANEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2675|beta-lactamase_L188Y|0.886649736 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTYRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2676|beta-lactamase_D48A|0.886599892 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELALNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2677|beta-lactamase_G154S|0.886372176 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMSDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2678|beta-lactamase_G85C|0.886315491 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDACQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2679|beta-lactamase_N168S|0.88597929 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELSEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2680|beta-lactamase_M153K|0.885936288 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNKGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2681|beta-lactamase_P253K|0.885898172 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKKSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2682|beta-lactamase_L150Y|0.885709548 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFYHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2683|beta-lactamase_N168A|0.8856802290000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELAEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2684|beta-lactamase_V101Y|0.8855258109999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLYEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2685|beta-lactamase_E277C|0.8855258109999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIACIGASLIKHW +>2686|beta-lactamase_P249T|0.8853147090000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGTDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2687|beta-lactamase_K213G|0.8852805020000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADGVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2688|beta-lactamase_E62S|0.8851378129999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPESRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2689|beta-lactamase_G194Y|0.885043989 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTYELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2690|beta-lactamase_E102K|0.885013692 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2691|beta-lactamase_D99D|0.884888059 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2692|beta-lactamase_A266F|0.884594419 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQFTMDERNRQIAEIGASLIKHW +>2693|beta-lactamase_P249E|0.884594419 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGEDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2694|beta-lactamase_E61C|0.884594419 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPCERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2695|beta-lactamase_Q4G|0.8845162329999999 +MSIGHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2696|beta-lactamase_M268S|0.88445173 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATSDERNRQIAEIGASLIKHW +>2697|beta-lactamase_L10P|0.884423387 +MSIQHFRVAPIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2698|beta-lactamase_A15Q|0.8843813620000001 +MSIQHFRVALIPFFQAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2699|beta-lactamase_R162T|0.884311972 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDTWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2700|beta-lactamase_L74V|0.8842113079999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLVCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2701|beta-lactamase_G263A|0.8840940290000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTASQATMDERNRQIAEIGASLIKHW +>2702|beta-lactamase_R238I|0.883973817 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEIGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2703|beta-lactamase_A40N|0.883780307 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGNRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2704|beta-lactamase_M153Y|0.883780307 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNYGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2705|beta-lactamase_G194W|0.883780307 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTWELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2706|beta-lactamase_V101F|0.883780307 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLFEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2707|beta-lactamase_R202H|0.883780307 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASHQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2708|beta-lactamase_Q4D|0.883780307 +MSIDHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2709|beta-lactamase_V8W|0.883780307 +MSIQHFRWALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2710|beta-lactamase_D174E|0.883573114 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNEERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2711|beta-lactamase_F58I|0.883482222 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESIRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2712|beta-lactamase_G90P|0.883482222 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLPRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2713|beta-lactamase_G43A|0.8833385559999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVAYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2714|beta-lactamase_R63V|0.8833053259999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEVFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2715|beta-lactamase_C121M|0.883291644 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELMSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2716|beta-lactamase_R162Q|0.883233004 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDQWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2717|beta-lactamase_S51Y|0.883061972 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNYGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2718|beta-lactamase_E119N|0.883061972 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRNLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2719|beta-lactamase_A211Y|0.882841097 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEYDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2720|beta-lactamase_M127H|0.882841097 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITHSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2721|beta-lactamase_F228I|0.88279223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWIIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2722|beta-lactamase_I3R|0.882467758 +MSRQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2723|beta-lactamase_L89L|0.882437861 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2724|beta-lactamase_T27C|0.8824228009999999 +MSIQHFRVALIPFFAAFCLPVFAHPECLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2725|beta-lactamase_M153E|0.8824228009999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNEGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2726|beta-lactamase_L28C|0.8824228009999999 +MSIQHFRVALIPFFAAFCLPVFAHPETCVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2727|beta-lactamase_S2V|0.8824228009999999 +MVIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2728|beta-lactamase_Q97Q|0.882314322 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2729|beta-lactamase_I54S|0.882253724 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKSLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2730|beta-lactamase_D99R|0.881968344 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNRLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2731|beta-lactamase_L111S|0.881851065 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHSTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2732|beta-lactamase_H110L|0.8814689309999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKLLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2733|beta-lactamase_R176L|0.881385858 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDELDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2734|beta-lactamase_F228K|0.881336992 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWKIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2735|beta-lactamase_E62N|0.881336992 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPENRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2736|beta-lactamase_R7E|0.881336992 +MSIQHFEVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2737|beta-lactamase_G216R|0.880955835 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVARPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2738|beta-lactamase_A124C|0.880783825 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSACITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2739|beta-lactamase_A77G|0.8807623240000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGGVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2740|beta-lactamase_S281G|0.8807525509999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAGLIKHW +>2741|beta-lactamase_C121A|0.880654818 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELASAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2742|beta-lactamase_D113L|0.880612793 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTLGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2743|beta-lactamase_L55E|0.8804486020000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIEESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2744|beta-lactamase_T147I|0.8801876559999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELIAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2745|beta-lactamase_A15A|0.879936917 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2746|beta-lactamase_R271G|0.879823114 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEGNRQIAEIGASLIKHW +>2747|beta-lactamase_G52N|0.879707789 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSNKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2748|beta-lactamase_E270Y|0.879707789 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDYRNRQIAEIGASLIKHW +>2749|beta-lactamase_F14S|0.879707789 +MSIQHFRVALIPFSAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2750|beta-lactamase_E87Q|0.879081323 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQQQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2751|beta-lactamase_V21G|0.878967953 +MSIQHFRVALIPFFAAFCLPGFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2752|beta-lactamase_F17S|0.878802785 +MSIQHFRVALIPFFAASCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2753|beta-lactamase_I3D|0.878802785 +MSDQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2754|beta-lactamase_I259M|0.87875001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVMYTTGSQATMDERNRQIAEIGASLIKHW +>2755|beta-lactamase_L192W|0.878544771 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLWTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2756|beta-lactamase_R91N|0.878544771 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGNRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2757|beta-lactamase_P217Y|0.878382535 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGYLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2758|beta-lactamase_F14F|0.878300658 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2759|beta-lactamase_M66C|0.8779837859999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPCMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2760|beta-lactamase_Y95L|0.8779573979999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHLSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2761|beta-lactamase_P25G|0.8779378520000001 +MSIQHFRVALIPFFAAFCLPVFAHGETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2762|beta-lactamase_L55N|0.8779104870000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKINESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2763|beta-lactamase_T267Y|0.877869439 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAYMDERNRQIAEIGASLIKHW +>2764|beta-lactamase_H5A|0.877869439 +MSIQAFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2765|beta-lactamase_D48Q|0.8778020040000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELQLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2766|beta-lactamase_I259C|0.877578196 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVCYTTGSQATMDERNRQIAEIGASLIKHW +>2767|beta-lactamase_A170D|0.877446257 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEDIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2768|beta-lactamase_G242S|0.8773758890000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRSIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2769|beta-lactamase_F228T|0.8773436379999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWTIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2770|beta-lactamase_V257C|0.8773123629999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRICVIYTTGSQATMDERNRQIAEIGASLIKHW +>2771|beta-lactamase_F149H|0.8773123629999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAHLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2772|beta-lactamase_A183G|0.8771227620000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAGMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2773|beta-lactamase_L188A|0.877111034 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTARKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2774|beta-lactamase_R7L|0.877109079 +MSIQHFLVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2775|beta-lactamase_R92C|0.876953685 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRCIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2776|beta-lactamase_A235A|0.876766673 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2777|beta-lactamase_T262D|0.876707398 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTDGSQATMDERNRQIAEIGASLIKHW +>2778|beta-lactamase_L111E|0.876707398 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHETDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2779|beta-lactamase_E195Y|0.876707398 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGYLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2780|beta-lactamase_S264N|0.8765754590000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGNQATMDERNRQIAEIGASLIKHW +>2781|beta-lactamase_T126D|0.8765754590000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIDMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2782|beta-lactamase_V101N|0.876450362 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLNEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2783|beta-lactamase_I140M|0.876217758 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTMGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2784|beta-lactamase_P249D|0.876217758 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGDDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2785|beta-lactamase_K109P|0.876217758 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEPHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2786|beta-lactamase_I11T|0.875917719 +MSIQHFRVALTPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2787|beta-lactamase_D161D|0.8758931959999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2788|beta-lactamase_M268N|0.875850283 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATNDERNRQIAEIGASLIKHW +>2789|beta-lactamase_L192T|0.875322527 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLTTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2790|beta-lactamase_D161S|0.875322527 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLSRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2791|beta-lactamase_S57I|0.8750537629999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEIFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2792|beta-lactamase_A9L|0.8748582970000001 +MSIQHFRVLLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2793|beta-lactamase_A124M|0.874821159 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAMITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2794|beta-lactamase_M115I|0.8747947709999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGITVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2795|beta-lactamase_G76T|0.874666742 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCTAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2796|beta-lactamase_T147A|0.8744888679999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELAAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2797|beta-lactamase_T198V|0.874438047 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLVLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2798|beta-lactamase_F149K|0.874355952 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAKLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2799|beta-lactamase_R202G|0.874219126 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASGQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2800|beta-lactamase_T261Q|0.874007047 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYQTGSQATMDERNRQIAEIGASLIKHW +>2801|beta-lactamase_C75S|0.873599502 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLSGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2802|beta-lactamase_P181V|0.873568227 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMVAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2803|beta-lactamase_L111D|0.873518384 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHDTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2804|beta-lactamase_G251W|0.873489064 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDWKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2805|beta-lactamase_I3A|0.873461699 +MSAQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2806|beta-lactamase_P20T|0.873461699 +MSIQHFRVALIPFFAAFCLTVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2807|beta-lactamase_V214N|0.8734431290000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKNAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2808|beta-lactamase_G85T|0.8733903540000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDATQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2809|beta-lactamase_M127D|0.8732486420000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITDSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2810|beta-lactamase_R63P|0.8731929340000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEPFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2811|beta-lactamase_T27S|0.87296033 +MSIQHFRVALIPFFAAFCLPVFAHPESLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2812|beta-lactamase_M153R|0.872866507 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNRGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2813|beta-lactamase_E46D|0.872673974 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIDLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2814|beta-lactamase_L47Q|0.872444302 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEQDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2815|beta-lactamase_V214S|0.8722029029999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKSAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2816|beta-lactamase_C75I|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLIGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2817|beta-lactamase_V78T|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGATLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2818|beta-lactamase_A170M|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEMIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2819|beta-lactamase_L192Y|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLYTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2820|beta-lactamase_S281W|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAWLIKHW +>2821|beta-lactamase_T139Y|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTYIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2822|beta-lactamase_V106F|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPFTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2823|beta-lactamase_V106W|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPWTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2824|beta-lactamase_F149Q|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAQLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2825|beta-lactamase_L28G|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETGVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2826|beta-lactamase_T147H|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELHAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2827|beta-lactamase_V101G|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLGEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2828|beta-lactamase_R63M|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEMFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2829|beta-lactamase_S51R|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNRGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2830|beta-lactamase_E62C|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPECRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2831|beta-lactamase_E62L|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPELRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2832|beta-lactamase_P217F|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGFLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2833|beta-lactamase_R159M|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTMLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2834|beta-lactamase_E270W|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDWRNRQIAEIGASLIKHW +>2835|beta-lactamase_R176Y|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEYDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2836|beta-lactamase_E26R|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPRTLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2837|beta-lactamase_E108C|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTCKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2838|beta-lactamase_D113I|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTIGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2839|beta-lactamase_D113W|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTWGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2840|beta-lactamase_Y103P|0.871563731 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEPSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2841|beta-lactamase_F22D|0.871563731 +MSIQHFRVALIPFFAAFCLPVDAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2842|beta-lactamase_R91S|0.871223622 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGSRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2843|beta-lactamase_V78L|0.8710301109999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGALLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2844|beta-lactamase_L135Q|0.870894263 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANQLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2845|beta-lactamase_V82W|0.870294185 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRWDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2846|beta-lactamase_M115Q|0.870243364 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGQTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2847|beta-lactamase_L38G|0.870052785 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQGGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2848|beta-lactamase_P217C|0.869849502 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGCLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2849|beta-lactamase_V106D|0.8697429729999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPDTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2850|beta-lactamase_M184L|0.869527961 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAALATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2851|beta-lactamase_M67H|0.869358884 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMHSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2852|beta-lactamase_D212Q|0.8692904709999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAQKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2853|beta-lactamase_V82Y|0.869057867 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRYDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2854|beta-lactamase_P165K|0.868885858 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEKELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2855|beta-lactamase_R7D|0.8686894159999999 +MSIQHFDVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2856|beta-lactamase_L49S|0.868232027 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDSNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2857|beta-lactamase_P165A|0.8681792509999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEAELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2858|beta-lactamase_A200W|0.8680737 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLWSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2859|beta-lactamase_A183P|0.8678528240000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAPMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2860|beta-lactamase_R159N|0.8674912140000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTNLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2861|beta-lactamase_I256M|0.8674345290000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRMVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2862|beta-lactamase_D99Y|0.867251769 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNYLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2863|beta-lactamase_M268G|0.867187265 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATGDERNRQIAEIGASLIKHW +>2864|beta-lactamase_D212N|0.867121785 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEANKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2865|beta-lactamase_I229L|0.867042621 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFLADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2866|beta-lactamase_M67I|0.867018188 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMISTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2867|beta-lactamase_G251I|0.86700646 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDIKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2868|beta-lactamase_I93I|0.8669936859999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2869|beta-lactamase_E62Q|0.866909705 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEQRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2870|beta-lactamase_N173P|0.866909705 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPPDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2871|beta-lactamase_A34A|0.86672839 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2872|beta-lactamase_G251V|0.866725968 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDVKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2873|beta-lactamase_L28N|0.866677101 +MSIQHFRVALIPFFAAFCLPVFAHPETNVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2874|beta-lactamase_T147M|0.866677101 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELMAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2875|beta-lactamase_Y103H|0.866677101 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEHSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2876|beta-lactamase_A222L|0.866594029 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSLLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2877|beta-lactamase_F70H|0.866420065 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTHKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2878|beta-lactamase_Y95M|0.866420065 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHMSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2879|beta-lactamase_R176W|0.866420065 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEWDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2880|beta-lactamase_K30F|0.866281284 +MSIQHFRVALIPFFAAFCLPVFAHPETLVFVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2881|beta-lactamase_G194V|0.86626076 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTVELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2882|beta-lactamase_L191C|0.8658151 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKCLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2883|beta-lactamase_W286M|0.8658151 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHM +>2884|beta-lactamase_G154A|0.865729095 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMADHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2885|beta-lactamase_P253D|0.8656147479999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKDSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2886|beta-lactamase_L38V|0.8655873829999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQVGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2887|beta-lactamase_G141H|0.865325459 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIHGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2888|beta-lactamase_S201C|0.8652580240000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLACRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2889|beta-lactamase_S104C|0.865170065 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYCPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2890|beta-lactamase_L137T|0.865047899 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLTTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2891|beta-lactamase_V21L|0.864860252 +MSIQHFRVALIPFFAAFCLPLFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2892|beta-lactamase_I54K|0.8648231140000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKKLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2893|beta-lactamase_P253W|0.864744928 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKWSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2894|beta-lactamase_H110E|0.864744928 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKELTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2895|beta-lactamase_L89Y|0.864705835 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQYGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2896|beta-lactamase_D48N|0.864705835 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELNLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2897|beta-lactamase_F228C|0.864482027 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWCIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2898|beta-lactamase_I259F|0.864324677 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVFYTTGSQATMDERNRQIAEIGASLIKHW +>2899|beta-lactamase_G154K|0.864324677 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMKDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2900|beta-lactamase_E87E|0.86429389 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2901|beta-lactamase_R189I|0.8642904709999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLIKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2902|beta-lactamase_T267F|0.8641096659999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAFMDERNRQIAEIGASLIKHW +>2903|beta-lactamase_L160N|0.86404614 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRNDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2904|beta-lactamase_D48H|0.86404614 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELHLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2905|beta-lactamase_V214I|0.86404614 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKIAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2906|beta-lactamase_E62F|0.86404614 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEFRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2907|beta-lactamase_R41D|0.86404614 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGADVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2908|beta-lactamase_L89P|0.863960135 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQPGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2909|beta-lactamase_V214L|0.863956226 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKLAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2910|beta-lactamase_L38A|0.8639484070000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQAGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2911|beta-lactamase_L111P|0.86392886 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHPTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2912|beta-lactamase_F13F|0.863613503 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2913|beta-lactamase_D99F|0.8633043490000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNFLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2914|beta-lactamase_L74I|0.86324571 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLICGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2915|beta-lactamase_F228V|0.8632105259999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWVIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2916|beta-lactamase_M268P|0.8631059520000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATPDERNRQIAEIGASLIKHW +>2917|beta-lactamase_F13P|0.863064904 +MSIQHFRVALIPPFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2918|beta-lactamase_T126K|0.8629906270000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIKMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2919|beta-lactamase_L38H|0.86287628 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQHGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2920|beta-lactamase_F14G|0.862785389 +MSIQHFRVALIPFGAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2921|beta-lactamase_S240T|0.8627023159999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGTRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2922|beta-lactamase_F17K|0.86267886 +MSIQHFRVALIPFFAAKCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2923|beta-lactamase_R176E|0.86251467 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEEDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2924|beta-lactamase_F228R|0.8624345290000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWRIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2925|beta-lactamase_K30N|0.862384685 +MSIQHFRVALIPFFAAFCLPVFAHPETLVNVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2926|beta-lactamase_A23P|0.862255678 +MSIQHFRVALIPFFAAFCLPVFPHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2927|beta-lactamase_T158F|0.8620289390000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVFRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2928|beta-lactamase_H285D|0.861871589 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKDW +>2929|beta-lactamase_Q203W|0.861790471 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRWQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2930|beta-lactamase_F228S|0.861758219 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWSIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2931|beta-lactamase_G279T|0.861276398 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEITASLIKHW +>2932|beta-lactamase_L89A|0.86112198 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQAGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2933|beta-lactamase_S201K|0.8607046620000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAKRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2934|beta-lactamase_Q204F|0.8607046620000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQFLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2935|beta-lactamase_G141K|0.8607046620000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIKGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2936|beta-lactamase_V106R|0.860608884 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPRTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2937|beta-lactamase_G236S|0.860560995 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2938|beta-lactamase_F22I|0.8604994229999999 +MSIQHFRVALIPFFAAFCLPVIAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2939|beta-lactamase_A123V|0.8603010259999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSVAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2940|beta-lactamase_S240Q|0.8602873440000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGQRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2941|beta-lactamase_L89I|0.8602560690000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQIGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2942|beta-lactamase_M1L|0.860232613 +LSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2943|beta-lactamase_A34G|0.8601720190000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDGEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2944|beta-lactamase_G216E|0.860127062 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAEPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2945|beta-lactamase_L10W|0.860065491 +MSIQHFRVAWIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2946|beta-lactamase_N168D|0.859957985 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELDEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2947|beta-lactamase_E87A|0.859849502 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQAQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2948|beta-lactamase_W227Y|0.8598358190000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGYFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2949|beta-lactamase_R41E|0.859717563 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAEVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2950|beta-lactamase_W286Y|0.859717563 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHY +>2951|beta-lactamase_G52E|0.85964524 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSEKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2952|beta-lactamase_A276I|0.8595142790000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIIEIGASLIKHW +>2953|beta-lactamase_L167N|0.8593471559999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPENNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2954|beta-lactamase_R202I|0.8593471559999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASIQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2955|beta-lactamase_D113F|0.8593471559999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTFGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2956|beta-lactamase_E62G|0.8589532940000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEGRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2957|beta-lactamase_R238D|0.8589190870000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEDGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2958|beta-lactamase_P165S|0.858704075 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWESELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2959|beta-lactamase_S240N|0.8586962570000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGNRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2960|beta-lactamase_S96P|0.8582633009999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYPQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2961|beta-lactamase_F14W|0.858236914 +MSIQHFRVALIPFWAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2962|beta-lactamase_V21I|0.858236914 +MSIQHFRVALIPFFAAFCLPIFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2963|beta-lactamase_R63Y|0.858198798 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEYFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2964|beta-lactamase_S264C|0.8579271009999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGCQATMDERNRQIAEIGASLIKHW +>2965|beta-lactamase_R63A|0.857780502 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEAFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2966|beta-lactamase_F6A|0.857780502 +MSIQHARVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2967|beta-lactamase_I11S|0.857746296 +MSIQHFRVALSPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2968|beta-lactamase_I244A|0.85763879 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIAAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2969|beta-lactamase_M66A|0.857601652 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPAMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2970|beta-lactamase_E46I|0.857601652 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIILDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2971|beta-lactamase_L38P|0.857601652 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQPGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2972|beta-lactamase_K30H|0.857601652 +MSIQHFRVALIPFFAAFCLPVFAHPETLVHVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2973|beta-lactamase_A148P|0.857490237 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTPFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2974|beta-lactamase_A183D|0.857303567 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPADMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2975|beta-lactamase_V72C|0.857261542 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKCLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2976|beta-lactamase_E87C|0.857261542 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQCQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2977|beta-lactamase_F149C|0.857106147 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTACLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2978|beta-lactamase_P181A|0.857097351 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMAAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2979|beta-lactamase_I3V|0.856881362 +MSVQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2980|beta-lactamase_P249H|0.856871589 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGHDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2981|beta-lactamase_A124G|0.856833473 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAGITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2982|beta-lactamase_P12D|0.856756265 +MSIQHFRVALIDFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2983|beta-lactamase_D48C|0.8567181490000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELCLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2984|beta-lactamase_P105V|0.856703489 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSVVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2985|beta-lactamase_G52A|0.85620603 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSAKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2986|beta-lactamase_F149E|0.856190393 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAELHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2987|beta-lactamase_T69H|0.8559832 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSHFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2988|beta-lactamase_G226Y|0.85580044 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAYWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2989|beta-lactamase_V214Q|0.855715412 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKQAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2990|beta-lactamase_A185C|0.855653841 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMCTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2991|beta-lactamase_L73H|0.855517993 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVHLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2992|beta-lactamase_P249C|0.855517993 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGCDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2993|beta-lactamase_R81T|0.855517993 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSTVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2994|beta-lactamase_T116C|0.8552746379999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMCVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2995|beta-lactamase_V106K|0.8552746379999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPKTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2996|beta-lactamase_L38C|0.8551612690000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQCGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2997|beta-lactamase_P224G|0.855071355 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALGAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2998|beta-lactamase_A170Q|0.8550459440000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEQIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>2999|beta-lactamase_D113P|0.854928665 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTPGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3000|beta-lactamase_K30E|0.8548778440000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVEVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3001|beta-lactamase_M1I|0.854809431 +ISIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3002|beta-lactamase_L136M|0.854713653 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLMLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3003|beta-lactamase_S254P|0.854478118 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPPRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3004|beta-lactamase_T198P|0.854272879 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLPLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3005|beta-lactamase_A230M|0.8540598220000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIMDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3006|beta-lactamase_D99W|0.85404614 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNWLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3007|beta-lactamase_P224K|0.853929838 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALKAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3008|beta-lactamase_V117T|0.8536688920000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTTRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3009|beta-lactamase_R271H|0.853646413 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEHNRQIAEIGASLIKHW +>3010|beta-lactamase_T198Y|0.8535604090000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLYLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3011|beta-lactamase_R81E|0.853521315 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSEVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3012|beta-lactamase_N98C|0.8534656079999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQCDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3013|beta-lactamase_M115C|0.853401104 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGCTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3014|beta-lactamase_T126R|0.8533874220000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIRMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3015|beta-lactamase_F64M|0.8533805809999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERMPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3016|beta-lactamase_P105I|0.853028743 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSIVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3017|beta-lactamase_S201S|0.852993515 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3018|beta-lactamase_G216V|0.8529056 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAVPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3019|beta-lactamase_I244T|0.852848915 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGITAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3020|beta-lactamase_Y44V|0.85283621 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGVIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3021|beta-lactamase_F149S|0.8526739740000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTASLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3022|beta-lactamase_R162K|0.8525606040000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDKWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3023|beta-lactamase_E108P|0.852466781 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTPKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3024|beta-lactamase_I283W|0.852442348 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLWKHW +>3025|beta-lactamase_N168T|0.852164787 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELTEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3026|beta-lactamase_L247C|0.8520172109999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAACGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3027|beta-lactamase_T262L|0.8520172109999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTLGSQATMDERNRQIAEIGASLIKHW +>3028|beta-lactamase_L100T|0.8520172109999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDTVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3029|beta-lactamase_G141D|0.8520172109999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIDGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3030|beta-lactamase_T178C|0.851871589 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDCTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3031|beta-lactamase_K144K|0.851840116 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3032|beta-lactamase_V82R|0.851832496 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRRDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3033|beta-lactamase_F13G|0.851163028 +MSIQHFRVALIPGFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3034|beta-lactamase_G226M|0.851158141 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAMWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3035|beta-lactamase_L191Y|0.851108297 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKYLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3036|beta-lactamase_R91A|0.850941175 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGARIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3037|beta-lactamase_G263Q|0.850620612 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTQSQATMDERNRQIAEIGASLIKHW +>3038|beta-lactamase_N168Q|0.850551222 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELQEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3039|beta-lactamase_T126N|0.8505394940000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAINMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3040|beta-lactamase_H5G|0.850514083 +MSIQGFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3041|beta-lactamase_T116A|0.850483786 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMAVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3042|beta-lactamase_R41W|0.850483786 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAWVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3043|beta-lactamase_V106T|0.850431988 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPTTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3044|beta-lactamase_S2G|0.8504173279999999 +MGIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3045|beta-lactamase_V82F|0.850368462 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRFDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3046|beta-lactamase_M184A|0.850317641 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAAATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3047|beta-lactamase_R63C|0.850317641 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEECFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3048|beta-lactamase_I3W|0.850317641 +MSWQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3049|beta-lactamase_P143V|0.8501847240000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGVKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3050|beta-lactamase_A15P|0.850062559 +MSIQHFRVALIPFFPAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3051|beta-lactamase_G141Q|0.849845592 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIQGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3052|beta-lactamase_F149R|0.849547508 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTARLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3053|beta-lactamase_L160Q|0.8493637709999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRQDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3054|beta-lactamase_S2D|0.849352043 +MDIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3055|beta-lactamase_P165M|0.849009978 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEMELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3056|beta-lactamase_V214R|0.849009978 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKRAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3057|beta-lactamase_T198F|0.849009978 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLFLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3058|beta-lactamase_F70G|0.8489405879999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTGKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3059|beta-lactamase_L223K|0.848849697 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAKPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3060|beta-lactamase_F70S|0.848224208 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTSKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3061|beta-lactamase_R176T|0.8482085709999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDETDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3062|beta-lactamase_G263R|0.84820173 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTRSQATMDERNRQIAEIGASLIKHW +>3063|beta-lactamase_G263H|0.8481929340000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTHSQATMDERNRQIAEIGASLIKHW +>3064|beta-lactamase_F58K|0.848107907 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESKRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3065|beta-lactamase_T147L|0.848082496 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELLAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3066|beta-lactamase_G52S|0.848064904 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSSKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3067|beta-lactamase_R159V|0.848049267 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTVLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3068|beta-lactamase_P143T|0.847939806 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGTKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3069|beta-lactamase_A183L|0.847823505 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPALMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3070|beta-lactamase_V106N|0.8477267490000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPNTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3071|beta-lactamase_D161H|0.847518579 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLHRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3072|beta-lactamase_A230I|0.847372957 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIIDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3073|beta-lactamase_L55W|0.8471305809999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIWESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3074|beta-lactamase_E102C|0.8471305809999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVCYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3075|beta-lactamase_D212G|0.847074873 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAGKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3076|beta-lactamase_I125T|0.8467660379999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAATTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3077|beta-lactamase_R91Q|0.8467660379999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGQRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3078|beta-lactamase_E35A|0.8463428559999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAADQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3079|beta-lactamase_I140T|0.846164005 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTTGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3080|beta-lactamase_Y260V|0.8461532540000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIVTTGSQATMDERNRQIAEIGASLIKHW +>3081|beta-lactamase_L73G|0.845282457 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVGLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3082|beta-lactamase_G226P|0.845267797 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAPWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3083|beta-lactamase_G154R|0.845140745 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMRDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3084|beta-lactamase_M268R|0.8450234659999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATRDERNRQIAEIGASLIKHW +>3085|beta-lactamase_L223S|0.8449814409999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSASPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3086|beta-lactamase_E46C|0.844909118 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYICLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3087|beta-lactamase_L247W|0.844415569 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAWGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3088|beta-lactamase_W208F|0.8441986020000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDFMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3089|beta-lactamase_D212S|0.8439982509999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEASKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3090|beta-lactamase_P143A|0.843873153 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGAKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3091|beta-lactamase_I283Q|0.8437539190000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLQKHW +>3092|beta-lactamase_R202M|0.8436405490000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASMQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3093|beta-lactamase_G263M|0.8436405490000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTMSQATMDERNRQIAEIGASLIKHW +>3094|beta-lactamase_D174S|0.84351252 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNSERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3095|beta-lactamase_P165R|0.843507633 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWERELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3096|beta-lactamase_I140A|0.84332976 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTAGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3097|beta-lactamase_V258T|0.843273075 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVTIYTTGSQATMDERNRQIAEIGASLIKHW +>3098|beta-lactamase_G142T|0.842605561 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGTPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3099|beta-lactamase_R162A|0.842575264 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDAWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3100|beta-lactamase_M115V|0.8425693999999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGVTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3101|beta-lactamase_V42Y|0.8423104090000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARYGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3102|beta-lactamase_L38N|0.8417474690000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQNGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3103|beta-lactamase_P165D|0.841700557 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEDELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3104|beta-lactamase_R176G|0.841383903 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEGDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3105|beta-lactamase_C18C|0.8411685790000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3106|beta-lactamase_L55G|0.840931401 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIGESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3107|beta-lactamase_L100C|0.8409030590000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDCVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3108|beta-lactamase_R63N|0.8409030590000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEENFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3109|beta-lactamase_L135T|0.840728118 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANTLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3110|beta-lactamase_E62R|0.840656773 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPERRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3111|beta-lactamase_F228H|0.840575655 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWHIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3112|beta-lactamase_P249V|0.8405267890000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGVDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3113|beta-lactamase_L74A|0.840037148 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLACGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3114|beta-lactamase_V72S|0.839800635 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKSLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3115|beta-lactamase_A123G|0.839142895 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSGAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3116|beta-lactamase_M66T|0.839097938 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPTMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3117|beta-lactamase_A34Y|0.838986523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDYEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3118|beta-lactamase_T27M|0.838986523 +MSIQHFRVALIPFFAAFCLPVFAHPEMLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3119|beta-lactamase_A77W|0.838986523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGWVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3120|beta-lactamase_R271D|0.838986523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEDNRQIAEIGASLIKHW +>3121|beta-lactamase_T139F|0.838986523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTFIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3122|beta-lactamase_Q204W|0.838986523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQWLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3123|beta-lactamase_G263E|0.838986523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTESQATMDERNRQIAEIGASLIKHW +>3124|beta-lactamase_R63F|0.838986523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEFFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3125|beta-lactamase_E62K|0.838986523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEKRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3126|beta-lactamase_A23C|0.838986523 +MSIQHFRVALIPFFAAFCLPVFCHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3127|beta-lactamase_D161T|0.838469517 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLTRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3128|beta-lactamase_D99C|0.8384607209999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNCLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3129|beta-lactamase_D161V|0.838455835 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLVRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3130|beta-lactamase_L38Q|0.838129408 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQQGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3131|beta-lactamase_I93Y|0.838111816 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRYHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3132|beta-lactamase_L74T|0.838105952 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLTCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3133|beta-lactamase_R162C|0.8380424259999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDCWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3134|beta-lactamase_V82K|0.837986718 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRKDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3135|beta-lactamase_R81G|0.837753137 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSGVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3136|beta-lactamase_T139W|0.837656382 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTWIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3137|beta-lactamase_G216I|0.837176515 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAIPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3138|beta-lactamase_R81I|0.837176515 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSIVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3139|beta-lactamase_P105L|0.837142308 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSLVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3140|beta-lactamase_E62I|0.8370699859999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEIRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3141|beta-lactamase_L38W|0.8369996190000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQWGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3142|beta-lactamase_M268K|0.8368588840000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATKDERNRQIAEIGASLIKHW +>3143|beta-lactamase_S201R|0.836554935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLARRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3144|beta-lactamase_L47F|0.836024247 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEFDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3145|beta-lactamase_P253E|0.836024247 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKESRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3146|beta-lactamase_P143S|0.8359323790000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGSKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3147|beta-lactamase_A215T|0.835821941 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVTGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3148|beta-lactamase_I256C|0.835792621 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRCVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3149|beta-lactamase_F64Y|0.8355570859999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERYPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3150|beta-lactamase_I243M|0.835295162 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGMIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3151|beta-lactamase_I45S|0.835107516 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYSELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3152|beta-lactamase_R81V|0.835041057 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSVVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3153|beta-lactamase_P249I|0.835035194 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGIDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3154|beta-lactamase_T116M|0.834914005 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMMVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3155|beta-lactamase_L111N|0.834914005 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHNTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3156|beta-lactamase_P217I|0.834914005 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGILLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3157|beta-lactamase_F6E|0.834914005 +MSIQHERVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3158|beta-lactamase_L160H|0.834713653 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRHDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3159|beta-lactamase_I283S|0.8343686570000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLSKHW +>3160|beta-lactamase_F228L|0.8343188140000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWLIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3161|beta-lactamase_L111G|0.83419567 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHGTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3162|beta-lactamase_A266W|0.834134099 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQWTMDERNRQIAEIGASLIKHW +>3163|beta-lactamase_A170E|0.833879017 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEEIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3164|beta-lactamase_T187F|0.8338672890000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATFLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3165|beta-lactamase_K213W|0.8335564990000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADWVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3166|beta-lactamase_V214H|0.833387422 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKHAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3167|beta-lactamase_D161C|0.833276984 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLCRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3168|beta-lactamase_L218L|0.83312246 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3169|beta-lactamase_A266I|0.833111816 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQITMDERNRQIAEIGASLIKHW +>3170|beta-lactamase_L89V|0.832649541 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQVGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3171|beta-lactamase_L150S|0.832575264 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFSHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3172|beta-lactamase_G154H|0.83247069 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMHDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3173|beta-lactamase_R59R|0.832036929 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3174|beta-lactamase_G226F|0.832023075 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAFWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3175|beta-lactamase_Y103G|0.83187843 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEGSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3176|beta-lactamase_D99G|0.831725968 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNGLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3177|beta-lactamase_G52K|0.831673192 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSKKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3178|beta-lactamase_M184C|0.831582301 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAACATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3179|beta-lactamase_T116R|0.831582301 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMRVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3180|beta-lactamase_E195A|0.831582301 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGALLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3181|beta-lactamase_L135A|0.831460135 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANALLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3182|beta-lactamase_M209C|0.831321355 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWCEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3183|beta-lactamase_I140F|0.831321355 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTFGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3184|beta-lactamase_S51V|0.831321355 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNVGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3185|beta-lactamase_D161A|0.8310594309999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLARWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3186|beta-lactamase_Y103N|0.830841487 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVENSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3187|beta-lactamase_L135F|0.830824873 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANFLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3188|beta-lactamase_P224T|0.830813145 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALTAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3189|beta-lactamase_A230S|0.830812168 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFISDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3190|beta-lactamase_A182P|0.83050431 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPPAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3191|beta-lactamase_L73Y|0.83035087 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVYLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3192|beta-lactamase_P165Q|0.8302883209999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEQELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3193|beta-lactamase_P12P|0.8302196359999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3194|beta-lactamase_L146A|0.829867093 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEATAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3195|beta-lactamase_L38E|0.82967847 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQEGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3196|beta-lactamase_P143Q|0.829442934 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGQKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3197|beta-lactamase_R255V|0.829348133 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSVIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3198|beta-lactamase_L10H|0.829151691 +MSIQHFRVAHIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3199|beta-lactamase_A222W|0.82907155 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSWLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3200|beta-lactamase_G85F|0.82907155 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAFQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3201|beta-lactamase_L247T|0.828805717 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAATGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3202|beta-lactamase_T198I|0.828621003 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLILASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3203|beta-lactamase_P224D|0.828437265 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALDAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3204|beta-lactamase_G242C|0.828279916 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRCIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3205|beta-lactamase_L28E|0.828127453 +MSIQHFRVALIPFFAAFCLPVFAHPETEVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3206|beta-lactamase_I54N|0.828127453 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKNLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3207|beta-lactamase_T116V|0.82796033 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMVVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3208|beta-lactamase_F22V|0.8278958270000001 +MSIQHFRVALIPFFAAFCLPVVAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3209|beta-lactamase_V82Q|0.827709158 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRQDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3210|beta-lactamase_E166P|0.827650518 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPPLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3211|beta-lactamase_G142N|0.82758406 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGNPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3212|beta-lactamase_L192A|0.82742671 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLATGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3213|beta-lactamase_C75M|0.8267699470000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLMGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3214|beta-lactamase_G43S|0.826722058 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVSYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3215|beta-lactamase_A185V|0.826598915 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMVTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3216|beta-lactamase_G141E|0.8264562259999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIEGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3217|beta-lactamase_M268E|0.8264562259999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATEDERNRQIAEIGASLIKHW +>3218|beta-lactamase_G76C|0.826160096 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCCAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3219|beta-lactamase_M115A|0.8260780000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGATVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3220|beta-lactamase_A235T|0.8260780000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGTGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3221|beta-lactamase_Y103A|0.82606725 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEASPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3222|beta-lactamase_F6P|0.825954857 +MSIQHPRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3223|beta-lactamase_T69S|0.8256411359999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSSFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3224|beta-lactamase_M127G|0.825308845 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITGSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3225|beta-lactamase_I125I|0.825051378 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3226|beta-lactamase_N130N|0.824939447 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3227|beta-lactamase_N168V|0.8248407059999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELVEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3228|beta-lactamase_T116K|0.824017797 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMKVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3229|beta-lactamase_A211I|0.824017797 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEIDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3230|beta-lactamase_V31T|0.823919087 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKTKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3231|beta-lactamase_G236N|0.823526202 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGANERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3232|beta-lactamase_P165E|0.8232232309999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEEELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3233|beta-lactamase_R92D|0.823076632 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRDIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3234|beta-lactamase_L135C|0.82294567 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANCLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3235|beta-lactamase_T261Y|0.82269743 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYYTGSQATMDERNRQIAEIGASLIKHW +>3236|beta-lactamase_G142S|0.82269743 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGSPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3237|beta-lactamase_R159D|0.82269743 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTDLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3238|beta-lactamase_R59Q|0.82269743 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFQPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3239|beta-lactamase_A16K|0.82269743 +MSIQHFRVALIPFFAKFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3240|beta-lactamase_C18F|0.82269743 +MSIQHFRVALIPFFAAFFLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3241|beta-lactamase_D174C|0.8223602520000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNCERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3242|beta-lactamase_L89W|0.821896022 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQWGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3243|beta-lactamase_P12E|0.821635076 +MSIQHFRVALIEFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3244|beta-lactamase_I93C|0.821574482 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRCHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3245|beta-lactamase_T27A|0.821560799 +MSIQHFRVALIPFFAAFCLPVFAHPEALVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3246|beta-lactamase_A246G|0.821513888 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAGLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3247|beta-lactamase_L197F|0.821050635 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELFTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3248|beta-lactamase_P165G|0.8204652170000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEGELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3249|beta-lactamase_P65A|0.8204114640000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFAMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3250|beta-lactamase_R7C|0.8203704159999999 +MSIQHFCVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3251|beta-lactamase_L55S|0.8201006740000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKISESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3252|beta-lactamase_P224E|0.8200918779999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALEAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3253|beta-lactamase_G141A|0.8197654520000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIAGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3254|beta-lactamase_T138P|0.8196159209999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLPTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3255|beta-lactamase_F13H|0.819327609 +MSIQHFRVALIPHFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3256|beta-lactamase_L10Q|0.818788125 +MSIQHFRVAQIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3257|beta-lactamase_I93F|0.818427492 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRFHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3258|beta-lactamase_L38D|0.818410878 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQDGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3259|beta-lactamase_G154C|0.818385467 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMCDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3260|beta-lactamase_V257T|0.818127453 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRITVIYTTGSQATMDERNRQIAEIGASLIKHW +>3261|beta-lactamase_R92G|0.817940784 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRGIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3262|beta-lactamase_D83S|0.8178968040000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVSAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3263|beta-lactamase_T261E|0.8178107990000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYETGSQATMDERNRQIAEIGASLIKHW +>3264|beta-lactamase_P25P|0.8176920529999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3265|beta-lactamase_N272E|0.8172674059999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERERQIAEIGASLIKHW +>3266|beta-lactamase_L167S|0.817089533 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPESNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3267|beta-lactamase_L137A|0.8170250290000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLATTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3268|beta-lactamase_F22T|0.816948798 +MSIQHFRVALIPFFAAFCLPVTAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3269|beta-lactamase_V42T|0.816642895 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARTGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3270|beta-lactamase_P143C|0.816323309 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGCKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3271|beta-lactamase_R176D|0.816280307 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEDDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3272|beta-lactamase_L120I|0.816243168 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREICSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3273|beta-lactamase_R159A|0.816181597 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTALDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3274|beta-lactamase_V106G|0.815872762 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPGTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3275|beta-lactamase_S264Q|0.81571639 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGQQATMDERNRQIAEIGASLIKHW +>3276|beta-lactamase_F6G|0.81571639 +MSIQHGRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3277|beta-lactamase_G85V|0.8154661940000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAVQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3278|beta-lactamase_C18Y|0.8151798379999999 +MSIQHFRVALIPFFAAFYLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3279|beta-lactamase_H24P|0.814271902 +MSIQHFRVALIPFFAAFCLPVFAPPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3280|beta-lactamase_S104G|0.814112598 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYGPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3281|beta-lactamase_E277W|0.814074482 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAWIGASLIKHW +>3282|beta-lactamase_A246E|0.8139659990000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAELGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3283|beta-lactamase_D174Q|0.813568227 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNQERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3284|beta-lactamase_T27Q|0.813534998 +MSIQHFRVALIPFFAAFCLPVFAHPEQLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3285|beta-lactamase_G141S|0.813534998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTISGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3286|beta-lactamase_L55A|0.81332585 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIAESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3287|beta-lactamase_L150W|0.8133092359999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFWHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3288|beta-lactamase_G234C|0.813267211 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSCAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3289|beta-lactamase_D174N|0.8132007529999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNNERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3290|beta-lactamase_L188S|0.8131645909999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTSRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3291|beta-lactamase_I3E|0.813162637 +MSEQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3292|beta-lactamase_L191A|0.8131528640000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKALTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3293|beta-lactamase_L146Y|0.8130013779999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEYTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3294|beta-lactamase_I140C|0.8129241690000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTCGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3295|beta-lactamase_I140Q|0.8129241690000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTQGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3296|beta-lactamase_R159I|0.8129241690000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTILDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3297|beta-lactamase_V42A|0.8128665070000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARAGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3298|beta-lactamase_N168C|0.8128147090000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELCEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3299|beta-lactamase_P224S|0.812795162 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALSAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3300|beta-lactamase_A170K|0.8127717059999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEKIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3301|beta-lactamase_D212T|0.81238664 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEATKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3302|beta-lactamase_D231A|0.8122771790000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAAKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3303|beta-lactamase_F70I|0.812265452 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTIKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3304|beta-lactamase_V78A|0.8121315579999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAALSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3305|beta-lactamase_L197K|0.811993755 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELKTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3306|beta-lactamase_P224H|0.811895045 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALHAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3307|beta-lactamase_R202N|0.811421042 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASNQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3308|beta-lactamase_L120C|0.81126076 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRECCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3309|beta-lactamase_I11I|0.811223378 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3310|beta-lactamase_M66Q|0.811156186 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPQMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3311|beta-lactamase_V21K|0.8109333559999999 +MSIQHFRVALIPFFAAFCLPKFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3312|beta-lactamase_L137C|0.8105140829999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLCTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3313|beta-lactamase_G263L|0.810480854 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTLSQATMDERNRQIAEIGASLIKHW +>3314|beta-lactamase_S201L|0.8103743259999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLALRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3315|beta-lactamase_K232R|0.810155405 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADRSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3316|beta-lactamase_R7R|0.810050708 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3317|beta-lactamase_T131L|0.809916937 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNLAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3318|beta-lactamase_T261H|0.809837774 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYHTGSQATMDERNRQIAEIGASLIKHW +>3319|beta-lactamase_R91Y|0.8095416440000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGYRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3320|beta-lactamase_E195W|0.809370612 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGWLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3321|beta-lactamase_L282Q|0.809328587 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASQIKHW +>3322|beta-lactamase_P143G|0.809301222 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGGKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3323|beta-lactamase_A15N|0.809123348 +MSIQHFRVALIPFFNAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3324|beta-lactamase_V214C|0.809060799 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKCAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3325|beta-lactamase_V82N|0.808803763 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRNDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3326|beta-lactamase_F6T|0.8086014559999999 +MSIQHTRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3327|beta-lactamase_S104T|0.808580932 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYTPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3328|beta-lactamase_L205V|0.8085701820000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQVIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3329|beta-lactamase_E119M|0.808324873 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRMLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3330|beta-lactamase_R91M|0.808324873 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGMRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3331|beta-lactamase_V82M|0.8081694779999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRMDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3332|beta-lactamase_G52M|0.80742671 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSMKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3333|beta-lactamase_L38K|0.807124717 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQKGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3334|beta-lactamase_V21N|0.807080737 +MSIQHFRVALIPFFAAFCLPNFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3335|beta-lactamase_R241K|0.806978118 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSKGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3336|beta-lactamase_P224Q|0.806659509 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALQAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3337|beta-lactamase_L79V|0.806408337 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVVSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3338|beta-lactamase_P105M|0.806408337 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSMVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3339|beta-lactamase_G39G|0.806118517 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3340|beta-lactamase_S240H|0.806013497 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGHRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3341|beta-lactamase_R81W|0.8059431290000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSWVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3342|beta-lactamase_T27P|0.8058874220000001 +MSIQHFRVALIPFFAAFCLPVFAHPEPLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3343|beta-lactamase_F149N|0.80561768 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTANLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3344|beta-lactamase_E119K|0.805471081 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRKLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3345|beta-lactamase_L191T|0.804631558 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKTLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3346|beta-lactamase_I283R|0.804224013 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLRKHW +>3347|beta-lactamase_G85W|0.804081323 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAWQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3348|beta-lactamase_P249L|0.803268188 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGLDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3349|beta-lactamase_R159E|0.803038516 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTELDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3350|beta-lactamase_P105Q|0.802918305 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSQVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3351|beta-lactamase_D48G|0.802649541 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELGLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3352|beta-lactamase_W208L|0.802368071 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDLMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3353|beta-lactamase_L89E|0.8021814009999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQEGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3354|beta-lactamase_A40V|0.8021540359999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGVRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3355|beta-lactamase_L282S|0.8021511040000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASSIKHW +>3356|beta-lactamase_F228Q|0.80175431 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWQIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3357|beta-lactamase_P105T|0.801652668 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSTVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3358|beta-lactamase_A230V|0.801642895 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIVDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3359|beta-lactamase_P224R|0.801243168 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALRAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3360|beta-lactamase_L47E|0.8011962570000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEEDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3361|beta-lactamase_G141M|0.80097929 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIMGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3362|beta-lactamase_I243Y|0.8009040359999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGYIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3363|beta-lactamase_A40W|0.8004857409999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGWRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3364|beta-lactamase_L89S|0.799825068 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQSGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3365|beta-lactamase_V214G|0.799771315 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKGAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3366|beta-lactamase_R176V|0.799637422 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEVDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3367|beta-lactamase_I54D|0.7991067340000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKDLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3368|beta-lactamase_P25A|0.799005092 +MSIQHFRVALIPFFAAFCLPVFAHAETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3369|beta-lactamase_L136A|0.7985936379999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLALTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3370|beta-lactamase_V101W|0.7982642790000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLWEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3371|beta-lactamase_E119T|0.796978118 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRTLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3372|beta-lactamase_L89G|0.796939025 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQGGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3373|beta-lactamase_T126H|0.796291057 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIHMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3374|beta-lactamase_R159W|0.796086796 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTWLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3375|beta-lactamase_D48M|0.796042817 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELMLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3376|beta-lactamase_F228N|0.7953997359999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWNIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3377|beta-lactamase_G263K|0.795284412 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTKSQATMDERNRQIAEIGASLIKHW +>3378|beta-lactamase_M66G|0.7950889459999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPGMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3379|beta-lactamase_P105E|0.794505483 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSEVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3380|beta-lactamase_G52H|0.794406773 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSHKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3381|beta-lactamase_R159C|0.7938975859999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTCLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3382|beta-lactamase_L135E|0.7938135359999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANELLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3383|beta-lactamase_D155N|0.793641527 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGNHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3384|beta-lactamase_P105K|0.7933776490000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSKVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3385|beta-lactamase_N168M|0.7931206120000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELMEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3386|beta-lactamase_V257A|0.792952512 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIAVIYTTGSQATMDERNRQIAEIGASLIKHW +>3387|beta-lactamase_L10N|0.792952512 +MSIQHFRVANIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3388|beta-lactamase_P224N|0.7928283909999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALNAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3389|beta-lactamase_R91E|0.792779525 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGERIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3390|beta-lactamase_S201Q|0.7927472729999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAQRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3391|beta-lactamase_G52Q|0.7927472729999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSQKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3392|beta-lactamase_T116I|0.792626085 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMIVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3393|beta-lactamase_L137S|0.792467758 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLSTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3394|beta-lactamase_M268D|0.7924472340000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATDDERNRQIAEIGASLIKHW +>3395|beta-lactamase_R241S|0.791879408 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSSGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3396|beta-lactamase_C75F|0.79160087 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLFGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3397|beta-lactamase_F149D|0.791552004 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTADLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3398|beta-lactamase_L89T|0.79154223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQTGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3399|beta-lactamase_R63E|0.791422996 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEEFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3400|beta-lactamase_G226W|0.7913350370000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAWWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3401|beta-lactamase_R220K|0.79119137 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLKSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3402|beta-lactamase_P105H|0.7908854670000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSHVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3403|beta-lactamase_R41C|0.790877649 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGACVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3404|beta-lactamase_L38R|0.790189611 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQRGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3405|beta-lactamase_Y103M|0.7901202209999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEMSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3406|beta-lactamase_A9E|0.7901202209999999 +MSIQHFRVELIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3407|beta-lactamase_C18L|0.7901202209999999 +MSIQHFRVALIPFFAAFLLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3408|beta-lactamase_E87S|0.7896139659999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQSQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3409|beta-lactamase_A246W|0.789572918 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAWLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3410|beta-lactamase_G141R|0.789516233 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIRGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3411|beta-lactamase_L47S|0.789226945 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIESDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3412|beta-lactamase_W208Y|0.7889640440000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDYMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3413|beta-lactamase_G154M|0.788867289 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMMDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3414|beta-lactamase_R159Y|0.788867289 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTYLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3415|beta-lactamase_V21F|0.788751964 +MSIQHFRVALIPFFAAFCLPFFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3416|beta-lactamase_R59A|0.788620025 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFAPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3417|beta-lactamase_R159L|0.7882613470000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTLLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3418|beta-lactamase_L120A|0.788203685 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREACSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3419|beta-lactamase_L197V|0.788151886 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELVTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3420|beta-lactamase_S104H|0.788047312 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYHPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3421|beta-lactamase_R91F|0.787793208 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGFRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3422|beta-lactamase_D161Q|0.787703294 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLQRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3423|beta-lactamase_P165H|0.787385663 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEHELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3424|beta-lactamase_A235L|0.7873240909999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGLGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3425|beta-lactamase_S264M|0.7871579459999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGMQATMDERNRQIAEIGASLIKHW +>3426|beta-lactamase_R162M|0.7871579459999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDMWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3427|beta-lactamase_P105A|0.7867015340000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSAVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3428|beta-lactamase_A23N|0.7860477029999999 +MSIQHFRVALIPFFAAFCLPVFNHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3429|beta-lactamase_H5F|0.7860477029999999 +MSIQFFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3430|beta-lactamase_H110T|0.785717367 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKTLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3431|beta-lactamase_F70T|0.785677297 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTTKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3432|beta-lactamase_V21R|0.785669478 +MSIQHFRVALIPFFAAFCLPRFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3433|beta-lactamase_V82L|0.7856518859999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRLDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3434|beta-lactamase_R176I|0.7855121290000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEIDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3435|beta-lactamase_G142D|0.785500401 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGDPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3436|beta-lactamase_T27H|0.785108493 +MSIQHFRVALIPFFAAFCLPVFAHPEHLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3437|beta-lactamase_L146W|0.784937461 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEWTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3438|beta-lactamase_R91D|0.784914005 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGDRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3439|beta-lactamase_I3G|0.7843021990000001 +MSGQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3440|beta-lactamase_T131M|0.784118462 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNMAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3441|beta-lactamase_R255M|0.784118462 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSMIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3442|beta-lactamase_Y103S|0.7839063820000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVESSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3443|beta-lactamase_P217W|0.783604388 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGWLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3444|beta-lactamase_C121L|0.7833053259999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELLSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3445|beta-lactamase_E56Y|0.7832515729999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILYSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3446|beta-lactamase_N130S|0.783235936 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDSTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3447|beta-lactamase_I256F|0.7831391809999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRFVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3448|beta-lactamase_A16E|0.782329955 +MSIQHFRVALIPFFAEFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3449|beta-lactamase_N130Y|0.7819751859999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDYTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3450|beta-lactamase_R255I|0.781407359 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSIIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3451|beta-lactamase_G114Y|0.78134872 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDYMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3452|beta-lactamase_G142E|0.781088751 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGEPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3453|beta-lactamase_G194I|0.780982222 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTIELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3454|beta-lactamase_P105R|0.78088449 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSRVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3455|beta-lactamase_R271E|0.780812168 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEENRQIAEIGASLIKHW +>3456|beta-lactamase_R255H|0.7806812059999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSHIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3457|beta-lactamase_A276D|0.780678274 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIDEIGASLIKHW +>3458|beta-lactamase_S51L|0.7805717459999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNLGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3459|beta-lactamase_L89C|0.780440784 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQCGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3460|beta-lactamase_A133C|0.7803469609999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTACNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3461|beta-lactamase_M66H|0.7800694 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPHMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3462|beta-lactamase_E87Y|0.7794693220000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQYQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3463|beta-lactamase_R41G|0.779311972 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAGVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3464|beta-lactamase_V78C|0.779186875 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGACLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3465|beta-lactamase_R81C|0.7788115809999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSCVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3466|beta-lactamase_A246Q|0.778800831 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAQLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3467|beta-lactamase_T267W|0.778800831 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAWMDERNRQIAEIGASLIKHW +>3468|beta-lactamase_N272G|0.778717758 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERGRQIAEIGASLIKHW +>3469|beta-lactamase_L74C|0.7784851540000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLCCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3470|beta-lactamase_V214F|0.778314122 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKFAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3471|beta-lactamase_K30W|0.778274052 +MSIQHFRVALIPFFAAFCLPVFAHPETLVWVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3472|beta-lactamase_V21D|0.778198798 +MSIQHFRVALIPFFAAFCLPDFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3473|beta-lactamase_N134D|0.7780551309999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAADLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3474|beta-lactamase_P105S|0.7772116990000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSSVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3475|beta-lactamase_G114S|0.7770621679999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDSMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3476|beta-lactamase_I140S|0.777056304 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTSGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3477|beta-lactamase_V82E|0.777053372 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSREDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3478|beta-lactamase_A23V|0.7769839820000001 +MSIQHFRVALIPFFAAFCLPVFVHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3479|beta-lactamase_W208D|0.776520729 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDDMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3480|beta-lactamase_D231Q|0.77640345 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAQKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3481|beta-lactamase_G52F|0.7763692440000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSFKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3482|beta-lactamase_V82G|0.776095592 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRGDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3483|beta-lactamase_T131V|0.775955835 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNVAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3484|beta-lactamase_G114A|0.775545358 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDAMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3485|beta-lactamase_D174G|0.775184724 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNGERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3486|beta-lactamase_P12R|0.7748358190000001 +MSIQHFRVALIRFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3487|beta-lactamase_V21E|0.774625694 +MSIQHFRVALIPFFAAFCLPEFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3488|beta-lactamase_G114H|0.773831128 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDHMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3489|beta-lactamase_G114N|0.773831128 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDNMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3490|beta-lactamase_S264K|0.773831128 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGKQATMDERNRQIAEIGASLIKHW +>3491|beta-lactamase_G52T|0.773831128 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSTKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3492|beta-lactamase_K30Y|0.773831128 +MSIQHFRVALIPFFAAFCLPVFAHPETLVYVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3493|beta-lactamase_G263T|0.773831128 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTTSQATMDERNRQIAEIGASLIKHW +>3494|beta-lactamase_L100Q|0.773831128 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDQVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3495|beta-lactamase_G141C|0.773831128 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTICGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3496|beta-lactamase_F13Q|0.773831128 +MSIQHFRVALIPQFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3497|beta-lactamase_P20G|0.773831128 +MSIQHFRVALIPFFAAFCLGVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3498|beta-lactamase_R7M|0.773831128 +MSIQHFMVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3499|beta-lactamase_T187Q|0.772312363 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATQLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3500|beta-lactamase_L218I|0.7722801109999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPILRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3501|beta-lactamase_L146C|0.772241996 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKECTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3502|beta-lactamase_N134Q|0.7721462179999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAQLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3503|beta-lactamase_S51C|0.771706421 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNCGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3504|beta-lactamase_F6D|0.771706421 +MSIQHDRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3505|beta-lactamase_F70L|0.7712460999999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTLKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3506|beta-lactamase_L136L|0.771187657 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3507|beta-lactamase_E46G|0.771179642 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIGLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3508|beta-lactamase_C121G|0.77091381 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELGSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3509|beta-lactamase_T187H|0.770308845 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATHLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3510|beta-lactamase_R162E|0.7697244040000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDEWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3511|beta-lactamase_H5S|0.7691771009999999 +MSIQSFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3512|beta-lactamase_H5W|0.768944498 +MSIQWFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3513|beta-lactamase_T27N|0.7680824959999999 +MSIQHFRVALIPFFAAFCLPVFAHPENLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3514|beta-lactamase_L89H|0.767956421 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQHGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3515|beta-lactamase_D161M|0.76772284 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLMRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3516|beta-lactamase_E169P|0.76772284 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNPAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3517|beta-lactamase_N272S|0.76752542 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERSRQIAEIGASLIKHW +>3518|beta-lactamase_G141T|0.76709051 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTITGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3519|beta-lactamase_D48T|0.766932183 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELTLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3520|beta-lactamase_M115T|0.766771902 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGTTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3521|beta-lactamase_P105Y|0.766313536 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSYVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3522|beta-lactamase_L100W|0.76601252 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDWVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3523|beta-lactamase_R255L|0.765940197 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSLIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3524|beta-lactamase_E87W|0.7658199859999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQWQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3525|beta-lactamase_S104N|0.76568707 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYNPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3526|beta-lactamase_A246N|0.765636249 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIANLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3527|beta-lactamase_D36P|0.7654055999999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEPQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3528|beta-lactamase_T158A|0.765217953 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVARLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3529|beta-lactamase_K32D|0.7649462570000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVDDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3530|beta-lactamase_E35S|0.7648553659999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDASDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3531|beta-lactamase_T262G|0.763967953 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTGGSQATMDERNRQIAEIGASLIKHW +>3532|beta-lactamase_I243F|0.76367671 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGFIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3533|beta-lactamase_C121I|0.763650323 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELISAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3534|beta-lactamase_L150N|0.763233982 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFNHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3535|beta-lactamase_L223R|0.76314309 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSARPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3536|beta-lactamase_V21Y|0.763091292 +MSIQHFRVALIPFFAAFCLPYFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3537|beta-lactamase_V257M|0.762972058 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIMVIYTTGSQATMDERNRQIAEIGASLIKHW +>3538|beta-lactamase_F70N|0.762748251 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTNKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3539|beta-lactamase_L218C|0.7625088059999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPCLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3540|beta-lactamase_L150Q|0.7623690479999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFQHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3541|beta-lactamase_F17R|0.762332887 +MSIQHFRVALIPFFAARCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3542|beta-lactamase_L89Q|0.7620054829999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQQGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3543|beta-lactamase_G76M|0.7616145520000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCMAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3544|beta-lactamase_D83G|0.76154614 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVGAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3545|beta-lactamase_R81D|0.761301808 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSDVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3546|beta-lactamase_V21H|0.760417328 +MSIQHFRVALIPFFAAFCLPHFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3547|beta-lactamase_A40L|0.75995603 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGLRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3548|beta-lactamase_T107M|0.759869048 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVMEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3549|beta-lactamase_Y103T|0.759615921 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVETSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3550|beta-lactamase_A245T|0.7594996190000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIITALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3551|beta-lactamase_N272A|0.759171237 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERARQIAEIGASLIKHW +>3552|beta-lactamase_I283H|0.7590480940000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLHKHW +>3553|beta-lactamase_Q86Q|0.7589868740000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3554|beta-lactamase_L197H|0.7586747559999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELHTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3555|beta-lactamase_L205F|0.758593638 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQFIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3556|beta-lactamase_L197Q|0.758593638 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELQTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3557|beta-lactamase_G52L|0.758461699 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSLKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3558|beta-lactamase_T69C|0.758457789 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSCFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3559|beta-lactamase_T131F|0.758400127 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNFAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3560|beta-lactamase_N130C|0.758400127 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDCTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3561|beta-lactamase_G236T|0.757359275 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGATERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3562|beta-lactamase_H110V|0.756584255 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKVLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3563|beta-lactamase_V21Q|0.756511933 +MSIQHFRVALIPFFAAFCLPQFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3564|beta-lactamase_K30G|0.756261738 +MSIQHFRVALIPFFAAFCLPVFAHPETLVGVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3565|beta-lactamase_C18P|0.756061386 +MSIQHFRVALIPFFAAFPLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3566|beta-lactamase_I275C|0.755556108 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQCAEIGASLIKHW +>3567|beta-lactamase_F70Q|0.755506265 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTQKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3568|beta-lactamase_L49P|0.755036171 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDPNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3569|beta-lactamase_P249Y|0.754284607 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGYDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3570|beta-lactamase_P181T|0.754144849 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMTAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3571|beta-lactamase_Q88P|0.754011933 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEPLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3572|beta-lactamase_V21M|0.753470495 +MSIQHFRVALIPFFAAFCLPMFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3573|beta-lactamase_T179C|0.753438243 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTCMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3574|beta-lactamase_I11P|0.752981832 +MSIQHFRVALPPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3575|beta-lactamase_D83A|0.7523094309999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVAAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3576|beta-lactamase_I45Q|0.752112989 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYQELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3577|beta-lactamase_L135K|0.7519742079999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANKLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3578|beta-lactamase_A123T|0.7518911359999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSTAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3579|beta-lactamase_L49G|0.7518911359999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDGNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3580|beta-lactamase_Y103V|0.751541253 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEVSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3581|beta-lactamase_T107G|0.74994137 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVGEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3582|beta-lactamase_V214Y|0.749699971 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKYAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3583|beta-lactamase_A23D|0.749397977 +MSIQHFRVALIPFFAAFCLPVFDHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3584|beta-lactamase_P224A|0.749251378 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALAAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3585|beta-lactamase_L73Q|0.748715803 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVQLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3586|beta-lactamase_I275Y|0.74796033 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQYAEIGASLIKHW +>3587|beta-lactamase_S2E|0.7477687740000001 +MEIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3588|beta-lactamase_G52Y|0.747176515 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSYKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3589|beta-lactamase_P65S|0.747040667 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFSMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3590|beta-lactamase_I283K|0.746614552 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLKKHW +>3591|beta-lactamase_P165F|0.7462109170000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEFELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3592|beta-lactamase_S201Y|0.74609657 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAYRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3593|beta-lactamase_M268C|0.745706616 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATCDERNRQIAEIGASLIKHW +>3594|beta-lactamase_T107I|0.745430033 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVIEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3595|beta-lactamase_L150G|0.745384099 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFGHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3596|beta-lactamase_W286F|0.744511347 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHF +>3597|beta-lactamase_E35D|0.744467367 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDADDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3598|beta-lactamase_E56W|0.744454662 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILWSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3599|beta-lactamase_L247F|0.744162441 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAFGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3600|beta-lactamase_L223F|0.74360732 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAFPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3601|beta-lactamase_E119R|0.743345397 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRRLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3602|beta-lactamase_L79I|0.7422351540000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVISRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3603|beta-lactamase_V21P|0.7421716279999999 +MSIQHFRVALIPFFAAFCLPPFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3604|beta-lactamase_E56I|0.7420250290000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILISFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3605|beta-lactamase_R91L|0.7416057559999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGLRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3606|beta-lactamase_L89D|0.741574482 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQDGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3607|beta-lactamase_G226L|0.741506069 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPALWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3608|beta-lactamase_L197R|0.741285194 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELRTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3609|beta-lactamase_A23K|0.741253919 +MSIQHFRVALIPFFAAFCLPVFKHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3610|beta-lactamase_S240D|0.741060409 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGDRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3611|beta-lactamase_G154T|0.740940197 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMTDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3612|beta-lactamase_A235V|0.740748642 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGVGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3613|beta-lactamase_R271P|0.739551417 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEPNRQIAEIGASLIKHW +>3614|beta-lactamase_I93Q|0.739337383 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRQHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3615|beta-lactamase_T158G|0.739217172 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVGRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3616|beta-lactamase_K252P|0.7385760459999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGPPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3617|beta-lactamase_E35G|0.738461699 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAGDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3618|beta-lactamase_F58E|0.7384450840000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESERPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3619|beta-lactamase_P105F|0.738291644 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSFVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3620|beta-lactamase_V214W|0.738075655 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKWAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3621|beta-lactamase_R202Y|0.737181401 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASYQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3622|beta-lactamase_G239N|0.736167914 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERNSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3623|beta-lactamase_L223Q|0.7353078670000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAQPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3624|beta-lactamase_A215P|0.734671628 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVPGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3625|beta-lactamase_F228G|0.734218149 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWGIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3626|beta-lactamase_R241T|0.734022684 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSTGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3627|beta-lactamase_G234M|0.734013888 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSMAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3628|beta-lactamase_P105N|0.734013888 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSNVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3629|beta-lactamase_G52R|0.7337128709999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSRKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3630|beta-lactamase_L191W|0.733588751 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKWLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3631|beta-lactamase_L100K|0.7331088840000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDKVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3632|beta-lactamase_L120V|0.7323407059999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREVCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3633|beta-lactamase_I11H|0.731672215 +MSIQHFRVALHPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3634|beta-lactamase_F17P|0.731480659 +MSIQHFRVALIPFFAAPCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3635|beta-lactamase_C75L|0.730549267 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLLGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3636|beta-lactamase_G141Y|0.7303948490000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIYGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3637|beta-lactamase_P143E|0.730227727 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGEKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3638|beta-lactamase_Q86P|0.7298231140000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGPEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3639|beta-lactamase_D174T|0.729528939 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNTERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3640|beta-lactamase_L28P|0.729498642 +MSIQHFRVALIPFFAAFCLPVFAHPETPVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3641|beta-lactamase_D231N|0.72940775 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIANKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3642|beta-lactamase_G279F|0.72940775 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIFASLIKHW +>3643|beta-lactamase_Y103C|0.7291057559999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVECSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3644|beta-lactamase_N168I|0.7284900409999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELIEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3645|beta-lactamase_G76V|0.728478313 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCVAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3646|beta-lactamase_A235N|0.728312168 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGNGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3647|beta-lactamase_E87N|0.7282222540000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQNQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3648|beta-lactamase_L10K|0.728058063 +MSIQHFRVAKIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3649|beta-lactamase_L197Y|0.727757047 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELYTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3650|beta-lactamase_G154Y|0.727537148 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMYDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3651|beta-lactamase_V72L|0.727220495 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKLLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3652|beta-lactamase_A9D|0.726868657 +MSIQHFRVDLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3653|beta-lactamase_V257Y|0.7257935990000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIYVIYTTGSQATMDERNRQIAEIGASLIKHW +>3654|beta-lactamase_T178V|0.725708571 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDVTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3655|beta-lactamase_I93H|0.7253899629999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRHHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3656|beta-lactamase_L73N|0.7249648259999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVNLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3657|beta-lactamase_N272Q|0.7249648259999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERQRQIAEIGASLIKHW +>3658|beta-lactamase_T262F|0.7249648259999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTFGSQATMDERNRQIAEIGASLIKHW +>3659|beta-lactamase_M115R|0.72457976 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGRTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3660|beta-lactamase_I11N|0.724532848 +MSIQHFRVALNPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3661|beta-lactamase_T116Y|0.7239679529999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMYVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3662|beta-lactamase_T178A|0.7235447709999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDATMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3663|beta-lactamase_R59S|0.723130385 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFSPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3664|beta-lactamase_L197C|0.7229564209999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELCTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3665|beta-lactamase_L247A|0.722919283 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAAGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3666|beta-lactamase_I229A|0.7228401190000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFAADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3667|beta-lactamase_D212H|0.7223925040000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAHKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3668|beta-lactamase_R91V|0.722115921 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGVRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3669|beta-lactamase_F228W|0.7217073979999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWWIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3670|beta-lactamase_A132G|0.7216800329999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTGANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3671|beta-lactamase_A40E|0.721055522 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGERVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3672|beta-lactamase_G76Y|0.720522879 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCYAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3673|beta-lactamase_E35C|0.720522879 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDACDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3674|beta-lactamase_D48V|0.7203840990000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELVLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3675|beta-lactamase_L49N|0.7200781959999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDNNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3676|beta-lactamase_S233P|0.720033239 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKPGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3677|beta-lactamase_V21W|0.71972929 +MSIQHFRVALIPFFAAFCLPWFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3678|beta-lactamase_G154L|0.719610057 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMLDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3679|beta-lactamase_D83T|0.7192787429999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVTAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3680|beta-lactamase_F22P|0.719216194 +MSIQHFRVALIPFFAAFCLPVPAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3681|beta-lactamase_I256A|0.718907359 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRAVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3682|beta-lactamase_L49H|0.718674756 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDHNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3683|beta-lactamase_P143I|0.718448993 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGIKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3684|beta-lactamase_Q204G|0.718301417 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQGLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3685|beta-lactamase_L10R|0.7179837859999999 +MSIQHFRVARIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3686|beta-lactamase_L137Q|0.717803958 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLQTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3687|beta-lactamase_I11R|0.717371003 +MSIQHFRVALRPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3688|beta-lactamase_E87G|0.717283043 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQGQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3689|beta-lactamase_I93T|0.717191175 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRTHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3690|beta-lactamase_V214P|0.717010369 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKPAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3691|beta-lactamase_P249G|0.716413223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGGDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3692|beta-lactamase_A230L|0.7163418779999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFILDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3693|beta-lactamase_L197S|0.7163418779999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELSTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3694|beta-lactamase_G76W|0.716079955 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCWAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3695|beta-lactamase_L167G|0.715963653 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEGNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3696|beta-lactamase_D174A|0.715945084 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNAERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3697|beta-lactamase_M67E|0.714385272 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMESTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3698|beta-lactamase_W286I|0.71332976 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHI +>3699|beta-lactamase_H110D|0.713078587 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKDLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3700|beta-lactamase_K30D|0.7127482509999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVDVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3701|beta-lactamase_N130D|0.71210517 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDDTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3702|beta-lactamase_G39P|0.711638008 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLPARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3703|beta-lactamase_L197N|0.711181597 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELNTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3704|beta-lactamase_L192S|0.710165178 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLSTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3705|beta-lactamase_R202L|0.710062559 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASLQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3706|beta-lactamase_R255T|0.709873935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSTIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3707|beta-lactamase_N134T|0.7095641220000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAATLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3708|beta-lactamase_P20C|0.709533825 +MSIQHFRVALIPFFAAFCLCVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3709|beta-lactamase_L49Q|0.7094165459999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDQNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3710|beta-lactamase_G76I|0.708675733 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCIAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3711|beta-lactamase_P165Y|0.708675733 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEYELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3712|beta-lactamase_Y103D|0.708675733 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEDSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3713|beta-lactamase_A23E|0.708675733 +MSIQHFRVALIPFFAAFCLPVFEHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3714|beta-lactamase_A215Q|0.707707203 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVQGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3715|beta-lactamase_R241G|0.707121785 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSGGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3716|beta-lactamase_A40D|0.7064552479999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGDRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3717|beta-lactamase_G216P|0.7064298379999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAPPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3718|beta-lactamase_P249F|0.706034998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGFDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3719|beta-lactamase_H110I|0.705714435 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKILTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3720|beta-lactamase_D99P|0.70560302 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNPLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3721|beta-lactamase_P165W|0.7055521990000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEWELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3722|beta-lactamase_Q274P|0.705418305 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRPIAEIGASLIKHW +>3723|beta-lactamase_T131Y|0.7040217059999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNYAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3724|beta-lactamase_L197T|0.703929838 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELTTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3725|beta-lactamase_A215N|0.70386338 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVNGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3726|beta-lactamase_A215K|0.70375001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVKGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3727|beta-lactamase_D231S|0.703664005 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIASKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3728|beta-lactamase_V82D|0.703211503 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRDDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3729|beta-lactamase_S264R|0.7027531370000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGRQATMDERNRQIAEIGASLIKHW +>3730|beta-lactamase_P20A|0.7024443020000001 +MSIQHFRVALIPFFAAFCLAVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3731|beta-lactamase_N168H|0.702225381 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELHEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3732|beta-lactamase_N168L|0.7021608779999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELLEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3733|beta-lactamase_V214E|0.702059236 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKEAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3734|beta-lactamase_V258G|0.702003528 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVGIYTTGSQATMDERNRQIAEIGASLIKHW +>3735|beta-lactamase_G141I|0.7018178359999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIIGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3736|beta-lactamase_I11K|0.7014640440000001 +MSIQHFRVALKPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3737|beta-lactamase_I11Q|0.699833864 +MSIQHFRVALQPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3738|beta-lactamase_N130G|0.698495905 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDGTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3739|beta-lactamase_I45H|0.698437265 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYHELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3740|beta-lactamase_P224C|0.698420651 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALCAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3741|beta-lactamase_C121S|0.698167523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELSSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3742|beta-lactamase_R162L|0.698167523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDLWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3743|beta-lactamase_G52W|0.69808836 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSWKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3744|beta-lactamase_I93E|0.6980570859999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRREHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3745|beta-lactamase_P181S|0.6975488759999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMSAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3746|beta-lactamase_Y95H|0.697230268 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHHSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3747|beta-lactamase_G279V|0.696674169 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIVASLIKHW +>3748|beta-lactamase_A124I|0.695950948 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAIITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3749|beta-lactamase_E164Y|0.695645045 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWYPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3750|beta-lactamase_G239S|0.6955150609999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERSSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3751|beta-lactamase_G76L|0.6951016520000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCLAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3752|beta-lactamase_L89N|0.6947361320000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQNGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3753|beta-lactamase_S264V|0.694714631 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGVQATMDERNRQIAEIGASLIKHW +>3754|beta-lactamase_L191H|0.694319791 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKHLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3755|beta-lactamase_R91G|0.693820377 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGGRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3756|beta-lactamase_A23R|0.692055326 +MSIQHFRVALIPFFAAFCLPVFRHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3757|beta-lactamase_F70Y|0.691530502 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTYKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3758|beta-lactamase_A245V|0.6914767490000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIVALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3759|beta-lactamase_F58G|0.691134685 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESGRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3760|beta-lactamase_F149G|0.6909157640000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAGLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3761|beta-lactamase_L100R|0.690471081 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDRVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3762|beta-lactamase_G279M|0.690060604 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIMASLIKHW +>3763|beta-lactamase_Q274D|0.690060604 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRDIAEIGASLIKHW +>3764|beta-lactamase_A16R|0.690060604 +MSIQHFRVALIPFFARFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3765|beta-lactamase_A215E|0.689554349 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVEGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3766|beta-lactamase_A215H|0.689425342 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVHGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3767|beta-lactamase_F64V|0.689014865 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERVPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3768|beta-lactamase_T27K|0.688916155 +MSIQHFRVALIPFFAAFCLPVFAHPEKLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3769|beta-lactamase_S264I|0.688736327 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGIQATMDERNRQIAEIGASLIKHW +>3770|beta-lactamase_G76F|0.6883151 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCFAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3771|beta-lactamase_P105G|0.6878938720000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSGVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3772|beta-lactamase_R220Q|0.68775216 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLQSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3773|beta-lactamase_D212A|0.6864220190000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAAKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3774|beta-lactamase_E119C|0.6852609559999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRCLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3775|beta-lactamase_Y103I|0.685189611 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEISPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3776|beta-lactamase_G114W|0.684983395 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDWMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3777|beta-lactamase_N130Q|0.684983395 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDQTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3778|beta-lactamase_Y103L|0.684983395 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVELSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3779|beta-lactamase_V257F|0.6836161159999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIFVIYTTGSQATMDERNRQIAEIGASLIKHW +>3780|beta-lactamase_G142Q|0.6836161159999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGQPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3781|beta-lactamase_D212P|0.683337578 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAPKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3782|beta-lactamase_D212K|0.682872371 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAKKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3783|beta-lactamase_A15E|0.6826690870000001 +MSIQHFRVALIPFFEAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3784|beta-lactamase_E87H|0.682472645 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQHQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3785|beta-lactamase_G263F|0.682206812 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTFSQATMDERNRQIAEIGASLIKHW +>3786|beta-lactamase_G236D|0.682168696 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGADERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3787|beta-lactamase_I54G|0.68197714 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKGLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3788|beta-lactamase_Y95P|0.681682965 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHPSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3789|beta-lactamase_Y103Q|0.681528548 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEQSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3790|beta-lactamase_E56F|0.680985154 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILFSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3791|beta-lactamase_E26E|0.6804126490000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3792|beta-lactamase_D212C|0.68029614 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEACKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3793|beta-lactamase_R118P|0.679251378 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVPELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3794|beta-lactamase_I45E|0.676098524 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYEELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3795|beta-lactamase_A246H|0.676098524 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAHLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3796|beta-lactamase_G142H|0.676098524 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGHPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3797|beta-lactamase_E35M|0.676098524 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAMDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3798|beta-lactamase_L100H|0.676098524 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDHVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3799|beta-lactamase_L55D|0.676098524 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIDESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3800|beta-lactamase_F17E|0.676098524 +MSIQHFRVALIPFFAAECLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3801|beta-lactamase_A215R|0.6757398459999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVRGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3802|beta-lactamase_D212R|0.674417523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEARKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3803|beta-lactamase_G85I|0.6743051309999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAIQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3804|beta-lactamase_D48L|0.673714826 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELLLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3805|beta-lactamase_E35V|0.672400323 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAVDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3806|beta-lactamase_N272C|0.67218922 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERCRQIAEIGASLIKHW +>3807|beta-lactamase_G263W|0.671722058 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTWSQATMDERNRQIAEIGASLIKHW +>3808|beta-lactamase_G52P|0.671656577 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSPKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3809|beta-lactamase_D83N|0.671485545 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVNAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3810|beta-lactamase_E46R|0.671211894 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIRLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3811|beta-lactamase_G279I|0.671086796 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIIASLIKHW +>3812|beta-lactamase_L146Q|0.6705492670000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEQTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3813|beta-lactamase_G114K|0.669435115 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDKMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3814|beta-lactamase_L167P|0.66894743 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEPNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3815|beta-lactamase_A15K|0.668357125 +MSIQHFRVALIPFFKAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3816|beta-lactamase_N272H|0.6681206120000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERHRQIAEIGASLIKHW +>3817|beta-lactamase_D231H|0.668075655 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAHKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3818|beta-lactamase_L167Q|0.668075655 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEQNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3819|beta-lactamase_A40I|0.667475577 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGIRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3820|beta-lactamase_D177N|0.667411073 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERNTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3821|beta-lactamase_L219P|0.667191175 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLPRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3822|beta-lactamase_A23T|0.665239455 +MSIQHFRVALIPFFAAFCLPVFTHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3823|beta-lactamase_G239A|0.665068423 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERASRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3824|beta-lactamase_S264D|0.664180033 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGDQATMDERNRQIAEIGASLIKHW +>3825|beta-lactamase_F228E|0.664018774 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWEIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3826|beta-lactamase_S264F|0.663881949 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGFQATMDERNRQIAEIGASLIKHW +>3827|beta-lactamase_T116F|0.663881949 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMFVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3828|beta-lactamase_W286L|0.663555522 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHL +>3829|beta-lactamase_L197A|0.663375694 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELATLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3830|beta-lactamase_P143N|0.663067836 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGNKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3831|beta-lactamase_R162R|0.662401288 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3832|beta-lactamase_P105W|0.6621364439999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSWVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3833|beta-lactamase_L89K|0.6613369920000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQKGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3834|beta-lactamase_S264E|0.661291057 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGEQATMDERNRQIAEIGASLIKHW +>3835|beta-lactamase_V29P|0.661226554 +MSIQHFRVALIPFFAAFCLPVFAHPETLPKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3836|beta-lactamase_G142A|0.6611903929999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGAPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3837|beta-lactamase_D231G|0.661070182 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAGKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3838|beta-lactamase_T27D|0.661062363 +MSIQHFRVALIPFFAAFCLPVFAHPEDLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3839|beta-lactamase_L135S|0.660937265 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANSLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3840|beta-lactamase_L100S|0.660461308 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDSVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3841|beta-lactamase_I243W|0.6601886339999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGWIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3842|beta-lactamase_S201F|0.659809431 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAFRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3843|beta-lactamase_D231E|0.659692152 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAEKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3844|beta-lactamase_P65N|0.65873535 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFNMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3845|beta-lactamase_M1V|0.658723622 +VSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3846|beta-lactamase_G114C|0.6586464129999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDCMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3847|beta-lactamase_V42N|0.658529134 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARNGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3848|beta-lactamase_G154P|0.658474404 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMPDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3849|beta-lactamase_M115S|0.658000401 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGSTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3850|beta-lactamase_A40F|0.658000401 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGFRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3851|beta-lactamase_A245M|0.657182379 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIMALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3852|beta-lactamase_G263P|0.657182379 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTPSQATMDERNRQIAEIGASLIKHW +>3853|beta-lactamase_K213P|0.657084646 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADPVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3854|beta-lactamase_V117C|0.657028939 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTCRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3855|beta-lactamase_F14H|0.657028939 +MSIQHFRVALIPFHAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3856|beta-lactamase_G279L|0.656552004 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEILASLIKHW +>3857|beta-lactamase_L191Q|0.655715412 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKQLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3858|beta-lactamase_R271F|0.65450646 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEFNRQIAEIGASLIKHW +>3859|beta-lactamase_L218V|0.654105756 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPVLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3860|beta-lactamase_R241Q|0.6536757329999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSQGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3861|beta-lactamase_R91W|0.6534529029999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGWRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3862|beta-lactamase_G141V|0.653294576 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIVGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3863|beta-lactamase_L47K|0.6526426989999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEKDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3864|beta-lactamase_L160P|0.65230259 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRPDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3865|beta-lactamase_M184Q|0.6516653729999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAQATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3866|beta-lactamase_S51I|0.6516653729999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNIGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3867|beta-lactamase_D231M|0.651371198 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAMKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3868|beta-lactamase_M67F|0.6511669370000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMFSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3869|beta-lactamase_R91C|0.650917719 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGCRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3870|beta-lactamase_R59C|0.650905014 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFCPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3871|beta-lactamase_L49K|0.64974395 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDKNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3872|beta-lactamase_N134K|0.649720495 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAKLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3873|beta-lactamase_D174M|0.649249423 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNMERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3874|beta-lactamase_G263V|0.649034412 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTVSQATMDERNRQIAEIGASLIKHW +>3875|beta-lactamase_R59M|0.648950362 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFMPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3876|beta-lactamase_P65H|0.6489317920000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFHMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3877|beta-lactamase_N134H|0.648611229 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAHLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3878|beta-lactamase_A40H|0.6484079460000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGHRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3879|beta-lactamase_P65V|0.648343442 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFVMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3880|beta-lactamase_R220A|0.6482075939999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLASALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3881|beta-lactamase_A123I|0.648175342 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSIAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3882|beta-lactamase_I259Y|0.647140354 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVYYTTGSQATMDERNRQIAEIGASLIKHW +>3883|beta-lactamase_L100A|0.6467787429999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDAVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3884|beta-lactamase_G141L|0.645768188 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTILGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3885|beta-lactamase_G154F|0.645001964 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMFDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3886|beta-lactamase_V78F|0.6447742470000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAFLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3887|beta-lactamase_L137E|0.644517211 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLETTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3888|beta-lactamase_D231T|0.64363664 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIATKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3889|beta-lactamase_S264Y|0.642664201 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGYQATMDERNRQIAEIGASLIKHW +>3890|beta-lactamase_D231C|0.642649541 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIACKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3891|beta-lactamase_R159G|0.6424315970000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTGLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3892|beta-lactamase_V117A|0.64241205 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTARELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3893|beta-lactamase_V29Y|0.639448798 +MSIQHFRVALIPFFAAFCLPVFAHPETLYKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3894|beta-lactamase_G114D|0.638144068 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDDMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3895|beta-lactamase_A235Q|0.637616312 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGQGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3896|beta-lactamase_L74E|0.637227336 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLECGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3897|beta-lactamase_D212E|0.6359431289999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAEKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3898|beta-lactamase_L79F|0.635424169 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVFSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3899|beta-lactamase_T69P|0.635172996 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSPFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3900|beta-lactamase_L150H|0.6348856629999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFHHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3901|beta-lactamase_L136C|0.634749814 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLCLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3902|beta-lactamase_F13K|0.634510369 +MSIQHFRVALIPKFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3903|beta-lactamase_L146T|0.633944498 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKETTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3904|beta-lactamase_G141F|0.6337959439999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIFGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3905|beta-lactamase_I140N|0.632773661 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTNGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3906|beta-lactamase_A123N|0.6324511429999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSNAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3907|beta-lactamase_D174V|0.631816859 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNVERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3908|beta-lactamase_T126W|0.631675147 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIWMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3909|beta-lactamase_L192Q|0.631237305 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLQTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3910|beta-lactamase_V117P|0.631110252 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTPRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3911|beta-lactamase_T116G|0.631076046 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMGVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3912|beta-lactamase_R91I|0.631028157 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGIRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3913|beta-lactamase_A215C|0.630866898 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVCGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3914|beta-lactamase_R241N|0.630669478 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSNGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3915|beta-lactamase_T126Y|0.6306616589999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIYMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3916|beta-lactamase_W286H|0.630351847 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHH +>3917|beta-lactamase_R255A|0.6297507920000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSAIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3918|beta-lactamase_I93A|0.62974786 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRAHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3919|beta-lactamase_L120T|0.629267993 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRETCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3920|beta-lactamase_V258S|0.629186875 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVSIYTTGSQATMDERNRQIAEIGASLIKHW +>3921|beta-lactamase_A123Y|0.629186875 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSYAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3922|beta-lactamase_N134S|0.6286855060000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAASLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3923|beta-lactamase_I125A|0.626413223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAATMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3924|beta-lactamase_D231I|0.626404427 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAIKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3925|beta-lactamase_H285I|0.62623535 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKIW +>3926|beta-lactamase_L192H|0.626146413 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLHTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3927|beta-lactamase_R241H|0.626050635 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSHGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3928|beta-lactamase_N134R|0.6257320270000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAARLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3929|beta-lactamase_L79C|0.625698798 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVCSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3930|beta-lactamase_I243T|0.625638204 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGTIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3931|beta-lactamase_A211P|0.624949189 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEPDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3932|beta-lactamase_D174H|0.62488664 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNHERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3933|beta-lactamase_P105D|0.6246599 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSDVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3934|beta-lactamase_G52V|0.624544576 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSVKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3935|beta-lactamase_R59Y|0.623974795 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFYPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3936|beta-lactamase_L135R|0.623099111 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANRLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3937|beta-lactamase_D155E|0.622790276 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGEHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3938|beta-lactamase_N152P|0.622502942 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHPMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3939|beta-lactamase_T131H|0.6223455920000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNHAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3940|beta-lactamase_L167F|0.621802199 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEFNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3941|beta-lactamase_T158V|0.6213682660000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVVRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3942|beta-lactamase_L137G|0.62135947 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLGTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3943|beta-lactamase_D83K|0.620435897 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVKAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3944|beta-lactamase_L197E|0.6202511829999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELETLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3945|beta-lactamase_D161Y|0.619088165 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLYRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3946|beta-lactamase_P65C|0.6189669760000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFCMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3947|beta-lactamase_P249W|0.618183161 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGWDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3948|beta-lactamase_A215Y|0.617817641 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVYGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3949|beta-lactamase_D231V|0.61735732 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAVKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3950|beta-lactamase_N272V|0.616866703 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERVRQIAEIGASLIKHW +>3951|beta-lactamase_Q37P|0.6164650220000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDPLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3952|beta-lactamase_R220S|0.616380971 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLSSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3953|beta-lactamase_L219D|0.615740823 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLDRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3954|beta-lactamase_L197G|0.6154231920000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELGTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3955|beta-lactamase_D48K|0.615015647 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELKLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3956|beta-lactamase_T198W|0.614731245 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLWLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3957|beta-lactamase_M66Y|0.614372566 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPYMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3958|beta-lactamase_R63W|0.614227922 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEWFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3959|beta-lactamase_L188G|0.614057867 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTGRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3960|beta-lactamase_S264L|0.613973817 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGLQATMDERNRQIAEIGASLIKHW +>3961|beta-lactamase_D174P|0.613879017 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNPERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3962|beta-lactamase_P224L|0.613820377 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALLAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3963|beta-lactamase_P181I|0.613247664 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMIAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3964|beta-lactamase_E195L|0.612859666 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGLLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3965|beta-lactamase_L219C|0.612217563 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLCRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3966|beta-lactamase_V117F|0.611801222 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTFRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3967|beta-lactamase_D231L|0.611532457 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIALKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3968|beta-lactamase_M153D|0.610943129 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNDGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3969|beta-lactamase_D83H|0.6099228010000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVHAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3970|beta-lactamase_L218G|0.609864161 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPGLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3971|beta-lactamase_D231Y|0.609341292 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAYKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3972|beta-lactamase_L137N|0.609262129 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLNTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3973|beta-lactamase_I140G|0.609201534 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTGGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3974|beta-lactamase_G52C|0.608507633 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSCKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3975|beta-lactamase_R63G|0.608119634 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEGFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3976|beta-lactamase_L160G|0.608020925 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRGDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3977|beta-lactamase_G114T|0.607685702 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDTMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3978|beta-lactamase_D48Y|0.607111034 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELYLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3979|beta-lactamase_A215V|0.606422996 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVVGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3980|beta-lactamase_R241A|0.6058727620000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSAGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3981|beta-lactamase_T261W|0.605514083 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYWTGSQATMDERNRQIAEIGASLIKHW +>3982|beta-lactamase_L188W|0.605068423 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTWRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3983|beta-lactamase_E46W|0.604428274 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIWLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3984|beta-lactamase_R241C|0.603989455 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSCGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3985|beta-lactamase_I278F|0.603277961 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEFGASLIKHW +>3986|beta-lactamase_L135H|0.6030981329999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANHLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3987|beta-lactamase_D161I|0.602915373 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLIRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3988|beta-lactamase_N168E|0.602422801 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELEEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3989|beta-lactamase_N134M|0.602138399 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAMLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3990|beta-lactamase_D48I|0.601391722 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELILNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3991|beta-lactamase_L219W|0.601361425 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLWRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3992|beta-lactamase_T147W|0.601239259 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELWAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3993|beta-lactamase_D231P|0.6004720579999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAPKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3994|beta-lactamase_L282E|0.60043492 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASEIKHW +>3995|beta-lactamase_P224Y|0.600372371 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALYAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3996|beta-lactamase_A123E|0.598842856 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSEAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3997|beta-lactamase_S104V|0.598470495 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYVPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3998|beta-lactamase_R241M|0.598243755 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSMGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>3999|beta-lactamase_L218F|0.597700362 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPFLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4000|beta-lactamase_R59G|0.597282066 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFGPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4001|beta-lactamase_N134C|0.596982027 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAACLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4002|beta-lactamase_P105C|0.596982027 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSCVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4003|beta-lactamase_L120F|0.596948798 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREFCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4004|beta-lactamase_S201V|0.59692241 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAVRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4005|beta-lactamase_A124N|0.596690784 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSANITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4006|beta-lactamase_D212V|0.5964337470000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAVKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4007|beta-lactamase_Y103R|0.595000987 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVERSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4008|beta-lactamase_T187W|0.5948377739999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATWLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4009|beta-lactamase_A266P|0.594247469 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQPTMDERNRQIAEIGASLIKHW +>4010|beta-lactamase_D231K|0.593914201 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAKKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4011|beta-lactamase_L219K|0.59355259 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLKRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4012|beta-lactamase_G142C|0.5930258110000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGCPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4013|beta-lactamase_G263I|0.592738477 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTISQATMDERNRQIAEIGASLIKHW +>4014|beta-lactamase_A235I|0.592254701 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGIGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4015|beta-lactamase_D174L|0.5922507920000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNLERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4016|beta-lactamase_P65K|0.592057281 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFKMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4017|beta-lactamase_N134A|0.591846179 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAALLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4018|beta-lactamase_L218T|0.59126467 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPTLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4019|beta-lactamase_R220H|0.589559236 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLHSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4020|beta-lactamase_P143R|0.589499619 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGRKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4021|beta-lactamase_N134V|0.587400323 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAVLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4022|beta-lactamase_L136T|0.587368071 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLTLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4023|beta-lactamase_R220G|0.5873622070000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLGSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4024|beta-lactamase_P20M|0.5872507920000001 +MSIQHFRVALIPFFAAFCLMVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4025|beta-lactamase_P181G|0.587225381 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMGAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4026|beta-lactamase_I283G|0.587112011 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLGKHW +>4027|beta-lactamase_G114L|0.586864748 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDLMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4028|beta-lactamase_G142K|0.5867425820000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGKPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4029|beta-lactamase_A34K|0.5865099779999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDKEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4030|beta-lactamase_L218A|0.586477727 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPALRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4031|beta-lactamase_G114E|0.58629008 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDEMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4032|beta-lactamase_G239H|0.5857418000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERHSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4033|beta-lactamase_T27F|0.585346961 +MSIQHFRVALIPFFAAFCLPVFAHPEFLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4034|beta-lactamase_T139P|0.585346961 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTPIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4035|beta-lactamase_I93K|0.584588556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRKHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4036|beta-lactamase_T147Y|0.584314904 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELYAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4037|beta-lactamase_G154V|0.5841145520000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMVDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4038|beta-lactamase_A124L|0.5839503620000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSALITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4039|beta-lactamase_Y260T|0.582690588 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVITTTGSQATMDERNRQIAEIGASLIKHW +>4040|beta-lactamase_P224M|0.582646609 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALMAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4041|beta-lactamase_G154W|0.582275225 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMWDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4042|beta-lactamase_P143M|0.5813731529999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGMKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4043|beta-lactamase_G43C|0.580856147 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVCYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4044|beta-lactamase_I243A|0.58082585 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGAIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4045|beta-lactamase_I140E|0.579668696 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTEGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4046|beta-lactamase_S264W|0.5796520820000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGWQATMDERNRQIAEIGASLIKHW +>4047|beta-lactamase_T187E|0.579084255 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATELRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4048|beta-lactamase_I229Y|0.578923974 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFYADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4049|beta-lactamase_D83C|0.578899541 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVCAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4050|beta-lactamase_G114Q|0.5783659210000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDQMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4051|beta-lactamase_P143L|0.5783659210000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGLKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4052|beta-lactamase_L100E|0.5783659210000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDEVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4053|beta-lactamase_A23Y|0.5783659210000001 +MSIQHFRVALIPFFAAFCLPVFYHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4054|beta-lactamase_L10E|0.5783659210000001 +MSIQHFRVAEIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4055|beta-lactamase_R176P|0.577950557 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEPDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4056|beta-lactamase_H151P|0.577636835 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLPNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4057|beta-lactamase_L188H|0.57748535 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTHRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4058|beta-lactamase_I140H|0.576862793 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTHGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4059|beta-lactamase_R59L|0.576750401 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFLPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4060|beta-lactamase_L191S|0.576703489 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKSLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4061|beta-lactamase_I259A|0.576521706 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVAYTTGSQATMDERNRQIAEIGASLIKHW +>4062|beta-lactamase_N134I|0.576426906 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAILLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4063|beta-lactamase_R59W|0.576411269 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFWPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4064|beta-lactamase_L73D|0.576391722 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVDLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4065|beta-lactamase_M115F|0.576169869 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGFTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4066|beta-lactamase_G142R|0.576005678 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGRPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4067|beta-lactamase_K109K|0.575988533 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4068|beta-lactamase_R241V|0.575442738 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSVGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4069|beta-lactamase_G226V|0.574890549 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAVWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4070|beta-lactamase_I278C|0.5746774920000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAECGASLIKHW +>4071|beta-lactamase_D48R|0.57425431 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELRLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4072|beta-lactamase_T178I|0.573805717 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDITMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4073|beta-lactamase_T69I|0.5736473910000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSIFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4074|beta-lactamase_N134Y|0.57317241 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAYLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4075|beta-lactamase_P65T|0.5710711589999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFTMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4076|beta-lactamase_I206D|0.571035975 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLDDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4077|beta-lactamase_L197P|0.571009588 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELPTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4078|beta-lactamase_D36Q|0.570221863 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEQQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4079|beta-lactamase_L137W|0.568884881 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLWTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4080|beta-lactamase_Y260C|0.568342465 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVICTTGSQATMDERNRQIAEIGASLIKHW +>4081|beta-lactamase_L219Q|0.56830044 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLQRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4082|beta-lactamase_T131N|0.568255483 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNNAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4083|beta-lactamase_R220V|0.568219322 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLVSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4084|beta-lactamase_L219S|0.56772284 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLSRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4085|beta-lactamase_P224V|0.567632926 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALVAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4086|beta-lactamase_V117N|0.56686768 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTNRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4087|beta-lactamase_L79A|0.566562754 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVASRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4088|beta-lactamase_C121V|0.56642886 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELVSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4089|beta-lactamase_Y95A|0.5663545839999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHASQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4090|beta-lactamase_Y44H|0.565961699 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGHIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4091|beta-lactamase_R271Y|0.565955835 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEYNRQIAEIGASLIKHW +>4092|beta-lactamase_R255C|0.565755483 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSCIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4093|beta-lactamase_I229F|0.564992191 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFFADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4094|beta-lactamase_P20V|0.564403841 +MSIQHFRVALIPFFAAFCLVVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4095|beta-lactamase_R255Q|0.563827219 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSQIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4096|beta-lactamase_L135Y|0.563824287 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANYLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4097|beta-lactamase_D231F|0.563822332 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAFKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4098|beta-lactamase_I259T|0.5638194000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVTYTTGSQATMDERNRQIAEIGASLIKHW +>4099|beta-lactamase_I283E|0.56370603 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLEKHW +>4100|beta-lactamase_M66S|0.563362989 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPSMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4101|beta-lactamase_T27G|0.56293492 +MSIQHFRVALIPFFAAFCLPVFAHPEGLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4102|beta-lactamase_E35R|0.562897781 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDARDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4103|beta-lactamase_A235C|0.562728704 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGCGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4104|beta-lactamase_A185T|0.561741605 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMTTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4105|beta-lactamase_L47H|0.560596179 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEHDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4106|beta-lactamase_I93W|0.560432965 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRWHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4107|beta-lactamase_L219A|0.560290276 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLARSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4108|beta-lactamase_E35T|0.5602677970000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDATDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4109|beta-lactamase_M115Y|0.5600410570000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGYTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4110|beta-lactamase_R255S|0.559824091 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSSIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4111|beta-lactamase_N168R|0.5597048570000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELREAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4112|beta-lactamase_T147P|0.55970388 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELPAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4113|beta-lactamase_P143F|0.559449775 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGFKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4114|beta-lactamase_A245L|0.559284607 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIILALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4115|beta-lactamase_D83M|0.559202512 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVMAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4116|beta-lactamase_S104R|0.559028548 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYRPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4117|beta-lactamase_E195I|0.5588194000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGILLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4118|beta-lactamase_L219N|0.5586815970000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLNRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4119|beta-lactamase_L49E|0.558081519 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDENSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4120|beta-lactamase_D174I|0.557834255 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNIERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4121|beta-lactamase_P65I|0.557450166 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFIMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4122|beta-lactamase_L282G|0.557348524 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASGIKHW +>4123|beta-lactamase_L218P|0.557219517 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPPLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4124|beta-lactamase_L219E|0.55711983 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLERSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4125|beta-lactamase_Y95C|0.556509978 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHCSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4126|beta-lactamase_L135N|0.556091683 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANNLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4127|beta-lactamase_L47W|0.556003724 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEWDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4128|beta-lactamase_L167H|0.55591381 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEHNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4129|beta-lactamase_L89R|0.555862011 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQRGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4130|beta-lactamase_R63D|0.555758415 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEDFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4131|beta-lactamase_E270P|0.555370416 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDPRNRQIAEIGASLIKHW +>4132|beta-lactamase_D161F|0.554995123 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLFRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4133|beta-lactamase_E35N|0.554775225 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDANDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4134|beta-lactamase_S233V|0.554250401 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKVGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4135|beta-lactamase_G248H|0.55393277 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALHPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4136|beta-lactamase_L49R|0.553277961 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDRNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4137|beta-lactamase_G239C|0.5532242079999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERCSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4138|beta-lactamase_W286N|0.553027766 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHN +>4139|beta-lactamase_N134F|0.5525498529999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAFLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4140|beta-lactamase_L146G|0.5520289389999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEGTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4141|beta-lactamase_D161G|0.5519185010000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLGRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4142|beta-lactamase_W208E|0.551821746 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDEMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4143|beta-lactamase_R271W|0.551333082 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEWNRQIAEIGASLIKHW +>4144|beta-lactamase_M209A|0.551091683 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWAEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4145|beta-lactamase_L167E|0.55074571 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEENEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4146|beta-lactamase_P65G|0.549432183 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFGMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4147|beta-lactamase_F64W|0.548941566 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERWPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4148|beta-lactamase_G236G|0.548745027 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4149|beta-lactamase_L223N|0.548444107 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSANPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4150|beta-lactamase_R202W|0.548379603 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASWQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4151|beta-lactamase_I93M|0.548294576 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRMHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4152|beta-lactamase_T27R|0.547771706 +MSIQHFRVALIPFFAAFCLPVFAHPERLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4153|beta-lactamase_A230W|0.547146218 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIWDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4154|beta-lactamase_S240M|0.546994732 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGMRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4155|beta-lactamase_L223G|0.546665373 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAGPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4156|beta-lactamase_T126F|0.545788712 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIFMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4157|beta-lactamase_I140W|0.545788712 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTWGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4158|beta-lactamase_I243E|0.54571639 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGEIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4159|beta-lactamase_I45G|0.545254115 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYGELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4160|beta-lactamase_T261G|0.54453578 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYGTGSQATMDERNRQIAEIGASLIKHW +>4161|beta-lactamase_G236C|0.544236718 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGACERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4162|beta-lactamase_V257S|0.5439875 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRISVIYTTGSQATMDERNRQIAEIGASLIKHW +>4163|beta-lactamase_W286Q|0.543461699 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHQ +>4164|beta-lactamase_L247Y|0.543357125 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAYGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4165|beta-lactamase_L219R|0.5433082579999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLRRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4166|beta-lactamase_R220T|0.5426358579999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLTSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4167|beta-lactamase_A215M|0.542110057 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVMGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4168|beta-lactamase_K190P|0.541955639 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRPLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4169|beta-lactamase_V31S|0.5418158820000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKSKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4170|beta-lactamase_L47G|0.541345788 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEGDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4171|beta-lactamase_G114P|0.540776984 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDPMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4172|beta-lactamase_A123H|0.540776984 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSHAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4173|beta-lactamase_W208C|0.540123153 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDCMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4174|beta-lactamase_P143K|0.538857516 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGKKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4175|beta-lactamase_A34H|0.538745123 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDHEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4176|beta-lactamase_D231R|0.538697234 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIARKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4177|beta-lactamase_P20Y|0.538548681 +MSIQHFRVALIPFFAAFCLYVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4178|beta-lactamase_G279Y|0.53838449 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIYASLIKHW +>4179|beta-lactamase_L223W|0.538239846 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAWPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4180|beta-lactamase_I244F|0.538233982 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIFAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4181|beta-lactamase_L28I|0.537643677 +MSIQHFRVALIPFFAAFCLPVFAHPETIVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4182|beta-lactamase_D83V|0.5371980160000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVVAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4183|beta-lactamase_G279W|0.536480659 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIWASLIKHW +>4184|beta-lactamase_C121T|0.535873739 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELTSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4185|beta-lactamase_T178M|0.535823896 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDMTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4186|beta-lactamase_T131P|0.535805326 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNPAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4187|beta-lactamase_T107N|0.5352482510000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVNEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4188|beta-lactamase_P224F|0.535236523 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALFAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4189|beta-lactamase_Y103E|0.535181792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEESPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4190|beta-lactamase_L219H|0.535123153 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLHRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4191|beta-lactamase_S281P|0.53508406 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAPLIKHW +>4192|beta-lactamase_W227M|0.534749814 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGMFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4193|beta-lactamase_L79Q|0.534618853 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVQSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4194|beta-lactamase_D177C|0.534037344 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERCTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4195|beta-lactamase_V78S|0.5340099779999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGASLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4196|beta-lactamase_A123M|0.533942543 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSMAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4197|beta-lactamase_N134G|0.533729486 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAGLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4198|beta-lactamase_R241L|0.532971081 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSLGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4199|beta-lactamase_I244S|0.5327873439999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGISAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4200|beta-lactamase_P253Y|0.532757047 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKYSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4201|beta-lactamase_T261K|0.5326192439999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYKTGSQATMDERNRQIAEIGASLIKHW +>4202|beta-lactamase_L205C|0.532443325 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQCIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4203|beta-lactamase_R162F|0.532214631 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDFWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4204|beta-lactamase_L218D|0.532094419 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPDLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4205|beta-lactamase_N272I|0.531826632 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERIRQIAEIGASLIKHW +>4206|beta-lactamase_A40K|0.5317826520000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGKRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4207|beta-lactamase_T178Q|0.53147284 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDQTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4208|beta-lactamase_L197W|0.531184529 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELWTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4209|beta-lactamase_M184T|0.530752551 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAATATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4210|beta-lactamase_A215I|0.5306254979999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVIGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4211|beta-lactamase_A185I|0.5303567339999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMITTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4212|beta-lactamase_I275T|0.530288321 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQTAEIGASLIKHW +>4213|beta-lactamase_D83R|0.53020818 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVRAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4214|beta-lactamase_P224I|0.529847547 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALIAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4215|beta-lactamase_L205W|0.529499619 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQWIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4216|beta-lactamase_L219T|0.529499619 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLTRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4217|beta-lactamase_Y44W|0.529499619 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGWIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4218|beta-lactamase_S201W|0.529499619 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAWRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4219|beta-lactamase_D33F|0.529499619 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKFAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4220|beta-lactamase_R59F|0.529499619 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFFPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4221|beta-lactamase_G248S|0.52891811 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALSPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4222|beta-lactamase_P181L|0.528838946 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMLAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4223|beta-lactamase_D174R|0.528770534 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNRERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4224|beta-lactamase_I283N|0.528611229 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLNKHW +>4225|beta-lactamase_V78E|0.5277834339999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAELSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4226|beta-lactamase_N168W|0.52772284 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELWEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4227|beta-lactamase_F13N|0.527434529 +MSIQHFRVALIPNFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4228|beta-lactamase_A246K|0.527413028 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAKLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4229|beta-lactamase_T178G|0.526996687 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDGTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4230|beta-lactamase_Y95T|0.5263194 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHTSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4231|beta-lactamase_R220N|0.52563234 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLNSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4232|beta-lactamase_W208N|0.525427101 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDNMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4233|beta-lactamase_W208A|0.525220885 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDAMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4234|beta-lactamase_S201P|0.5248895720000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAPRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4235|beta-lactamase_I45R|0.524876867 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYRELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4236|beta-lactamase_L282N|0.5247234270000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASNIKHW +>4237|beta-lactamase_D212Y|0.524693129 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAYKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4238|beta-lactamase_I93R|0.524134099 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRRHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4239|beta-lactamase_R255E|0.524069595 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSEIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4240|beta-lactamase_V117Q|0.523750987 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTQRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4241|beta-lactamase_M115K|0.5235623629999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGKTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4242|beta-lactamase_R59E|0.523391331 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFEPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4243|beta-lactamase_I125N|0.5232349589999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAANTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4244|beta-lactamase_P65Q|0.522784412 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFQMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4245|beta-lactamase_A84P|0.522071941 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDPGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4246|beta-lactamase_L218N|0.521881362 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPNLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4247|beta-lactamase_R220F|0.521846179 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLFSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4248|beta-lactamase_I259W|0.521355561 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVWYTTGSQATMDERNRQIAEIGASLIKHW +>4249|beta-lactamase_T179A|0.520886444 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTAMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4250|beta-lactamase_A40Y|0.520614748 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGYRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4251|beta-lactamase_W208I|0.520450557 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDIMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4252|beta-lactamase_W208H|0.520388986 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDHMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4253|beta-lactamase_A215F|0.520255092 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVFGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4254|beta-lactamase_L10D|0.520142699 +MSIQHFRVADIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4255|beta-lactamase_F14Q|0.520102629 +MSIQHFRVALIPFQAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4256|beta-lactamase_T131E|0.519726358 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNEAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4257|beta-lactamase_R220C|0.5193246770000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLCSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4258|beta-lactamase_D174Y|0.519212285 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNYERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4259|beta-lactamase_I125S|0.5184832 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAASTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4260|beta-lactamase_E35K|0.518442152 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAKDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4261|beta-lactamase_M115E|0.51835517 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGETVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4262|beta-lactamase_L197D|0.5181196339999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELDTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4263|beta-lactamase_E35I|0.5172830429999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAIDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4264|beta-lactamase_A34N|0.517043599 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDNEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4265|beta-lactamase_I93N|0.516998642 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRNHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4266|beta-lactamase_G248A|0.5167279220000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALAPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4267|beta-lactamase_A40P|0.51638879 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGPRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4268|beta-lactamase_T261N|0.516313536 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYNTGSQATMDERNRQIAEIGASLIKHW +>4269|beta-lactamase_T27E|0.515537539 +MSIQHFRVALIPFFAAFCLPVFAHPEELVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4270|beta-lactamase_S240F|0.515399736 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGFRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4271|beta-lactamase_R162Y|0.5149716670000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDYWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4272|beta-lactamase_G52I|0.514952121 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSIKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4273|beta-lactamase_W208Q|0.5148817529999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDQMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4274|beta-lactamase_V78H|0.514839728 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAHLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4275|beta-lactamase_L100G|0.514839728 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDGVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4276|beta-lactamase_I256Y|0.5147996579999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRYVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4277|beta-lactamase_R241I|0.514766429 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSIGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4278|beta-lactamase_L73E|0.514627649 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVELCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4279|beta-lactamase_T69V|0.513610252 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSVFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4280|beta-lactamase_L47R|0.512999423 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIERDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4281|beta-lactamase_L137H|0.512724795 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLHTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4282|beta-lactamase_D177G|0.51255474 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERGTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4283|beta-lactamase_I125H|0.5122087670000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAHTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4284|beta-lactamase_A123L|0.5121599 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSLAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4285|beta-lactamase_G226I|0.5120680320000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAIWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4286|beta-lactamase_H110P|0.510797508 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKPLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4287|beta-lactamase_I243Q|0.510501378 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGQIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4288|beta-lactamase_I140K|0.5102492279999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTKGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4289|beta-lactamase_I93S|0.509253333 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRSHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4290|beta-lactamase_T261R|0.509007047 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYRTGSQATMDERNRQIAEIGASLIKHW +>4291|beta-lactamase_L223H|0.508920065 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAHPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4292|beta-lactamase_S264P|0.508893677 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGPQATMDERNRQIAEIGASLIKHW +>4293|beta-lactamase_V72G|0.50858191 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKGLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4294|beta-lactamase_N130T|0.5075449670000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDTTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4295|beta-lactamase_G279N|0.506945866 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEINASLIKHW +>4296|beta-lactamase_V117H|0.505066468 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTHRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4297|beta-lactamase_E119Y|0.505066468 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRYLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4298|beta-lactamase_R220L|0.504987305 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLLSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4299|beta-lactamase_L218Q|0.5047156079999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPQLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4300|beta-lactamase_D231W|0.504538712 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAWKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4301|beta-lactamase_T158C|0.504325655 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVCRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4302|beta-lactamase_A246D|0.504212285 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIADLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4303|beta-lactamase_L120S|0.503963067 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRESCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4304|beta-lactamase_L205A|0.503956226 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQAIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4305|beta-lactamase_E145E|0.503816606 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4306|beta-lactamase_V78Q|0.503708962 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAQLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4307|beta-lactamase_V117Y|0.503393286 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTYRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4308|beta-lactamase_A16D|0.502845006 +MSIQHFRVALIPFFADFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4309|beta-lactamase_D161L|0.50213449 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLLRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4310|beta-lactamase_N272M|0.501576437 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERMRQIAEIGASLIKHW +>4311|beta-lactamase_R220M|0.501307672 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLMSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4312|beta-lactamase_V117S|0.5007281179999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTSRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4313|beta-lactamase_L100N|0.500179838 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDNVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4314|beta-lactamase_A23W|0.500179838 +MSIQHFRVALIPFFAAFCLPVFWHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4315|beta-lactamase_A230Y|0.499004115 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIYDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4316|beta-lactamase_A34E|0.498854584 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDEEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4317|beta-lactamase_I45N|0.498175342 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYNELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4318|beta-lactamase_W208T|0.497802981 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDTMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4319|beta-lactamase_F17D|0.497629994 +MSIQHFRVALIPFFAADCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4320|beta-lactamase_P65L|0.496884294 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFLMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4321|beta-lactamase_L167D|0.496481636 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEDNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4322|beta-lactamase_G242N|0.496434724 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRNIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4323|beta-lactamase_R202F|0.496181597 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASFQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4324|beta-lactamase_L120H|0.495669478 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREHCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4325|beta-lactamase_R241E|0.495558063 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSEGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4326|beta-lactamase_G114R|0.494935506 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDRMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4327|beta-lactamase_S104Y|0.4945953970000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYYPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4328|beta-lactamase_D174F|0.494398954 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNFERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4329|beta-lactamase_Y95G|0.493269165 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHGSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4330|beta-lactamase_L218S|0.493058063 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPSLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4331|beta-lactamase_L223Y|0.492993559 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAYPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4332|beta-lactamase_M184S|0.490406577 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAASATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4333|beta-lactamase_T187Y|0.490406577 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATYLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4334|beta-lactamase_G141W|0.489518188 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIWGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4335|beta-lactamase_L218H|0.489244537 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPHLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4336|beta-lactamase_K284P|0.487275225 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIPHW +>4337|beta-lactamase_T69M|0.48714915 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSMFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4338|beta-lactamase_P143Y|0.486741605 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGYKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4339|beta-lactamase_S240Y|0.486701534 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGYRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4340|beta-lactamase_Y44C|0.486298876 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGCIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4341|beta-lactamase_D48F|0.486271511 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELFLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4342|beta-lactamase_M209F|0.484705835 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWFEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4343|beta-lactamase_T69A|0.483830151 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSAFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4344|beta-lactamase_A235E|0.483736327 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGEGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4345|beta-lactamase_M115N|0.483348329 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGNTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4346|beta-lactamase_V72F|0.482906577 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKFLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4347|beta-lactamase_G114V|0.481797312 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDVMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4348|beta-lactamase_M180P|0.481554935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTPPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4349|beta-lactamase_L73L|0.48099346 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4350|beta-lactamase_S51P|0.480633317 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNPGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4351|beta-lactamase_E119L|0.480633317 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRLLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4352|beta-lactamase_D174K|0.479719517 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNKERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4353|beta-lactamase_A245F|0.479152668 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIFALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4354|beta-lactamase_R220I|0.479106734 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLISALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4355|beta-lactamase_A40R|0.478898563 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGRRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4356|beta-lactamase_G248N|0.478638595 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALNPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4357|beta-lactamase_L188Q|0.478411855 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTQRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4358|beta-lactamase_L191E|0.477991605 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKELTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4359|beta-lactamase_R220E|0.477794185 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLESALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4360|beta-lactamase_W208S|0.476421042 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDSMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4361|beta-lactamase_P224W|0.473956226 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALWAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4362|beta-lactamase_I11E|0.472968149 +MSIQHFRVALEPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4363|beta-lactamase_P20F|0.472814709 +MSIQHFRVALIPFFAAFCLFVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4364|beta-lactamase_K53P|0.472790276 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGPILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4365|beta-lactamase_T69Y|0.471748446 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSYFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4366|beta-lactamase_R220D|0.470905991 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLDSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4367|beta-lactamase_N168F|0.470694889 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELFEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4368|beta-lactamase_M209W|0.470345983 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWWEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4369|beta-lactamase_D83I|0.470152473 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVIAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4370|beta-lactamase_T158M|0.469774247 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVMRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4371|beta-lactamase_P65Y|0.469356929 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFYMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4372|beta-lactamase_T178N|0.469135076 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDNTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4373|beta-lactamase_S201I|0.468998251 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAIRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4374|beta-lactamase_L219Y|0.46747069 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLYRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4375|beta-lactamase_I278T|0.466927297 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAETGASLIKHW +>4376|beta-lactamase_F228D|0.464891527 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWDIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4377|beta-lactamase_N168Y|0.464640354 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELYEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4378|beta-lactamase_N130A|0.464612011 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDATAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4379|beta-lactamase_V42S|0.464344224 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARSGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4380|beta-lactamase_N272R|0.464344224 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERRRQIAEIGASLIKHW +>4381|beta-lactamase_V78W|0.463181206 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAWLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4382|beta-lactamase_P65F|0.462786366 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFFMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4383|beta-lactamase_L282Y|0.462715999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASYIKHW +>4384|beta-lactamase_M115H|0.461086796 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGHTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4385|beta-lactamase_V78Y|0.458154818 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAYLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4386|beta-lactamase_V31F|0.458079564 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKFKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4387|beta-lactamase_I229T|0.458079564 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFTADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4388|beta-lactamase_E35H|0.458079564 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAHDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4389|beta-lactamase_D161K|0.456796335 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLKRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4390|beta-lactamase_A132C|0.456200166 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTCANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4391|beta-lactamase_D212M|0.456200166 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAMKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4392|beta-lactamase_P143D|0.456200166 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGDKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4393|beta-lactamase_L205T|0.455502355 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQTIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4394|beta-lactamase_R202D|0.454570964 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASDQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4395|beta-lactamase_L73W|0.453978704 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVWLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4396|beta-lactamase_L47N|0.453978704 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIENDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4397|beta-lactamase_D48W|0.453485154 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELWLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4398|beta-lactamase_I256T|0.451833473 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRTVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4399|beta-lactamase_T131Q|0.450561972 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNQAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4400|beta-lactamase_L219G|0.450181792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLGRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4401|beta-lactamase_M209G|0.450091878 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWGEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4402|beta-lactamase_L218Y|0.448376671 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPYLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4403|beta-lactamase_D161W|0.448056108 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLWRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4404|beta-lactamase_E87K|0.447906577 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQKQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4405|beta-lactamase_I229S|0.447489259 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFSADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4406|beta-lactamase_S128G|0.447463849 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMGDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4407|beta-lactamase_G239Q|0.445729095 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERQSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4408|beta-lactamase_D161R|0.445022488 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLRRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4409|beta-lactamase_K213D|0.444877844 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADDVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4410|beta-lactamase_L74S|0.444576828 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLSCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4411|beta-lactamase_L79S|0.444144849 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVSSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4412|beta-lactamase_W227A|0.444044185 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGAFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4413|beta-lactamase_P20L|0.442208767 +MSIQHFRVALIPFFAAFCLLVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4414|beta-lactamase_A215L|0.442081714 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVLGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4415|beta-lactamase_V31V|0.440873792 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4416|beta-lactamase_K30P|0.438031675 +MSIQHFRVALIPFFAAFCLPVFAHPETLVPVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4417|beta-lactamase_V117E|0.4369654120000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTERELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4418|beta-lactamase_L191N|0.436209939 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKNLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4419|beta-lactamase_V31W|0.436209939 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKWKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4420|beta-lactamase_A235Y|0.435413419 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGYGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4421|beta-lactamase_R220W|0.435221863 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLWSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4422|beta-lactamase_L79T|0.434316859 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVTSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4423|beta-lactamase_W286P|0.433377649 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHP +>4424|beta-lactamase_D212I|0.433343442 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAIKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4425|beta-lactamase_G279Q|0.431767015 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIQASLIKHW +>4426|beta-lactamase_L49D|0.431767015 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDDNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4427|beta-lactamase_L223P|0.429848524 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAPPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4428|beta-lactamase_D83Y|0.429387226 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVYAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4429|beta-lactamase_S233C|0.428628821 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKCGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4430|beta-lactamase_L192G|0.428191957 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLGTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4431|beta-lactamase_L135W|0.428008219 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANWLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4432|beta-lactamase_C121Q|0.427325068 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELQSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4433|beta-lactamase_G236E|0.426825655 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAEERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4434|beta-lactamase_P20I|0.426712285 +MSIQHFRVALIPFFAAFCLIVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4435|beta-lactamase_R241F|0.426336992 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSFGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4436|beta-lactamase_A133V|0.425807281 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAVNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4437|beta-lactamase_A235R|0.424001183 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGRGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4438|beta-lactamase_S201D|0.422935897 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLADRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4439|beta-lactamase_R220Y|0.422828391 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLYSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4440|beta-lactamase_T69L|0.422551808 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSLFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4441|beta-lactamase_N168K|0.422168696 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELKEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4442|beta-lactamase_L120Q|0.421993755 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREQCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4443|beta-lactamase_L160D|0.421993755 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRDDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4444|beta-lactamase_N134E|0.421335037 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAELLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4445|beta-lactamase_R220P|0.420739846 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLPSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4446|beta-lactamase_E119F|0.41955044 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRFLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4447|beta-lactamase_A9A|0.419222736 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4448|beta-lactamase_W286E|0.418611229 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHE +>4449|beta-lactamase_F64L|0.416730854 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERLPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4450|beta-lactamase_M115G|0.416730854 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGGTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4451|beta-lactamase_Y103K|0.4154779220000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEKSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4452|beta-lactamase_L188N|0.414885663 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTNRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4453|beta-lactamase_Y44A|0.414484959 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGAIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4454|beta-lactamase_S104K|0.414427297 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYKPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4455|beta-lactamase_A215W|0.414314904 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVWGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4456|beta-lactamase_I140D|0.412220495 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTDGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4457|beta-lactamase_A230F|0.411858884 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIFDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4458|beta-lactamase_T131W|0.410823896 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNWAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4459|beta-lactamase_F64Q|0.410823896 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERQPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4460|beta-lactamase_D174W|0.410823896 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNWERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4461|beta-lactamase_L79Y|0.410308845 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVYSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4462|beta-lactamase_A34P|0.409314904 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDPEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4463|beta-lactamase_G236Q|0.406980072 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAQERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4464|beta-lactamase_Q204P|0.404172215 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQPLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4465|beta-lactamase_V31G|0.402769752 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKGKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4466|beta-lactamase_G114I|0.402447234 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDIMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4467|beta-lactamase_T27Y|0.402447234 +MSIQHFRVALIPFFAAFCLPVFAHPEYLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4468|beta-lactamase_I140R|0.402219517 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTRGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4469|beta-lactamase_M209T|0.401083864 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWTEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4470|beta-lactamase_R162V|0.400352824 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDVWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4471|beta-lactamase_D212F|0.399655014 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAFKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4472|beta-lactamase_F14N|0.398171433 +MSIQHFRVALIPFNAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4473|beta-lactamase_N272K|0.397504896 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERKRQIAEIGASLIKHW +>4474|beta-lactamase_M209Q|0.396862793 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWQEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4475|beta-lactamase_L192N|0.396862793 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLNTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4476|beta-lactamase_T158I|0.3961082970000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVIRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4477|beta-lactamase_G242M|0.395648954 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRMIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4478|beta-lactamase_T179V|0.394684333 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTVMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4479|beta-lactamase_G279E|0.394474208 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIEASLIKHW +>4480|beta-lactamase_I275W|0.393759783 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQWAEIGASLIKHW +>4481|beta-lactamase_Q203C|0.393759783 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRCQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4482|beta-lactamase_A245I|0.392499032 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIIALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4483|beta-lactamase_Y95S|0.390552199 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHSSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4484|beta-lactamase_D212W|0.390139767 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAWKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4485|beta-lactamase_A235H|0.389687265 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGHGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4486|beta-lactamase_L218E|0.38750001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPELRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4487|beta-lactamase_R59T|0.386696648 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFTPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4488|beta-lactamase_T147F|0.386270534 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELFAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4489|beta-lactamase_E87R|0.385425147 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQRQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4490|beta-lactamase_I229N|0.383729486 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFNADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4491|beta-lactamase_I243H|0.383466585 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGHIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4492|beta-lactamase_C75N|0.382900713 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLNGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4493|beta-lactamase_V258N|0.382900713 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVNIYTTGSQATMDERNRQIAEIGASLIKHW +>4494|beta-lactamase_V42H|0.382900713 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARHGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4495|beta-lactamase_A235K|0.382900713 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGKGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4496|beta-lactamase_L218R|0.381142504 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPRLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4497|beta-lactamase_P65M|0.3805737 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFMMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4498|beta-lactamase_L223E|0.380211112 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAEPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4499|beta-lactamase_G239T|0.379612989 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERTSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4500|beta-lactamase_W286R|0.378976749 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHR +>4501|beta-lactamase_I229W|0.378828196 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFWADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4502|beta-lactamase_R255F|0.3786513 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSFIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4503|beta-lactamase_A235D|0.378578 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGDGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4504|beta-lactamase_T69G|0.378458767 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSGFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4505|beta-lactamase_A235F|0.378458767 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGFGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4506|beta-lactamase_G154I|0.378458767 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMIDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4507|beta-lactamase_L79N|0.377983786 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVNSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4508|beta-lactamase_F70E|0.377757047 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTEKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4509|beta-lactamase_L120Y|0.37608191 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREYCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4510|beta-lactamase_F14P|0.375749619 +MSIQHFRVALIPFPAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4511|beta-lactamase_I283P|0.375159314 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLPKHW +>4512|beta-lactamase_S240V|0.374876867 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGVRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4513|beta-lactamase_V214D|0.374812363 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKDAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4514|beta-lactamase_G239D|0.374604193 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERDSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4515|beta-lactamase_Y260S|0.374062754 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVISTTGSQATMDERNRQIAEIGASLIKHW +>4516|beta-lactamase_L218W|0.373381558 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPWLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4517|beta-lactamase_V31N|0.373127453 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKNKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4518|beta-lactamase_P20W|0.373127453 +MSIQHFRVALIPFFAAFCLWVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4519|beta-lactamase_R255G|0.372775616 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSGIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4520|beta-lactamase_F64I|0.3723348420000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERIPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4521|beta-lactamase_W227S|0.371730854 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGSFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4522|beta-lactamase_I243D|0.371047703 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGDIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4523|beta-lactamase_H285P|0.369735154 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKPW +>4524|beta-lactamase_C18K|0.368938634 +MSIQHFRVALIPFFAAFKLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4525|beta-lactamase_T126P|0.367543012 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIPMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4526|beta-lactamase_L74G|0.36661162 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLGCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4527|beta-lactamase_F58D|0.36661162 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESDRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4528|beta-lactamase_L79E|0.36638879 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVESRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4529|beta-lactamase_L160Y|0.366265647 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRYDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4530|beta-lactamase_L282K|0.365653841 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASKIKHW +>4531|beta-lactamase_N134L|0.36480259 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAALLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4532|beta-lactamase_W286K|0.364717563 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHK +>4533|beta-lactamase_R241Y|0.364594419 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSYGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4534|beta-lactamase_W227H|0.364105756 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGHFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4535|beta-lactamase_Y260W|0.363897586 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIWTTGSQATMDERNRQIAEIGASLIKHW +>4536|beta-lactamase_L218K|0.363557477 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPKLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4537|beta-lactamase_S104D|0.363354193 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYDPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4538|beta-lactamase_I93P|0.362087578 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRPHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4539|beta-lactamase_A215D|0.361810018 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVDGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4540|beta-lactamase_N168P|0.361620416 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELPEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4541|beta-lactamase_W286D|0.361521706 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHD +>4542|beta-lactamase_Y260A|0.360384099 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIATTGSQATMDERNRQIAEIGASLIKHW +>4543|beta-lactamase_A246R|0.360370416 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIARLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4544|beta-lactamase_G236H|0.358467563 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAHERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4545|beta-lactamase_N134W|0.35624609999999995 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAWLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4546|beta-lactamase_V257E|0.355568814 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIEVIYTTGSQATMDERNRQIAEIGASLIKHW +>4547|beta-lactamase_M184H|0.354977531 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAHATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4548|beta-lactamase_A133P|0.354296335 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAPNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4549|beta-lactamase_W208V|0.354104779 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDVMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4550|beta-lactamase_N272L|0.353580932 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERLRQIAEIGASLIKHW +>4551|beta-lactamase_E35L|0.353580932 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDALDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4552|beta-lactamase_S57P|0.353301417 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEPFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4553|beta-lactamase_L74Q|0.353251573 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLQCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4554|beta-lactamase_V157P|0.352829369 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHPTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4555|beta-lactamase_I275A|0.352495123 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQAAEIGASLIKHW +>4556|beta-lactamase_G236I|0.351529525 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAIERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4557|beta-lactamase_L136S|0.350788712 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLSLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4558|beta-lactamase_A124Q|0.350323505 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAQITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4559|beta-lactamase_V258F|0.350323505 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVFIYTTGSQATMDERNRQIAEIGASLIKHW +>4560|beta-lactamase_D83L|0.349923778 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVLAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4561|beta-lactamase_F70K|0.349528939 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTKKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4562|beta-lactamase_I243S|0.349397 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGSIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4563|beta-lactamase_L205Q|0.348406968 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQQIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4564|beta-lactamase_L205E|0.3470651 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQEIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4565|beta-lactamase_R255N|0.346599892 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSNIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4566|beta-lactamase_L167K|0.346250987 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEKNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4567|beta-lactamase_G242T|0.346203098 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRTIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4568|beta-lactamase_S240L|0.345495514 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGLRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4569|beta-lactamase_G239M|0.343871198 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERMSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4570|beta-lactamase_I256G|0.343807672 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRGVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4571|beta-lactamase_I243N|0.343460721 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGNIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4572|beta-lactamase_R59D|0.343392308 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFDPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4573|beta-lactamase_P65E|0.34293589700000005 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFEMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4574|beta-lactamase_L282H|0.342623153 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASHIKHW +>4575|beta-lactamase_M1T|0.34217847 +TSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4576|beta-lactamase_L160K|0.341488477 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRKDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4577|beta-lactamase_G239R|0.34115618600000003 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERRSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4578|beta-lactamase_I229H|0.339957985 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFHADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4579|beta-lactamase_L135G|0.339693129 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANGLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4580|beta-lactamase_F64C|0.33964230799999995 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERCPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4581|beta-lactamase_G239K|0.33961885299999994 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERKSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4582|beta-lactamase_M209I|0.338688438 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWIEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4583|beta-lactamase_G242H|0.337591878 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRHIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4584|beta-lactamase_S104I|0.33752444299999995 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYIPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4585|beta-lactamase_A15D|0.33708855600000004 +MSIQHFRVALIPFFDAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4586|beta-lactamase_G236M|0.335989064 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAMERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4587|beta-lactamase_G239F|0.335192543 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERFSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4588|beta-lactamase_D212L|0.334785975 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEALKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4589|beta-lactamase_I125F|0.334034412 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAFTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4590|beta-lactamase_V101P|0.334034412 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLPEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4591|beta-lactamase_M209S|0.333206616 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWSEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4592|beta-lactamase_W227C|0.331001769 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGCFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4593|beta-lactamase_V257W|0.330915764 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIWVIYTTGSQATMDERNRQIAEIGASLIKHW +>4594|beta-lactamase_F14K|0.330915764 +MSIQHFRVALIPFKAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4595|beta-lactamase_S233W|0.330493559 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKWGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4596|beta-lactamase_S104P|0.330459353 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYPPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4597|beta-lactamase_A34R|0.329784998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDREDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4598|beta-lactamase_A230T|0.329093051 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFITDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4599|beta-lactamase_G248C|0.328467563 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALCPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4600|beta-lactamase_V78N|0.32747069 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGANLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4601|beta-lactamase_T178L|0.327367093 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDLTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4602|beta-lactamase_R255Y|0.327053372 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSYIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4603|beta-lactamase_A123D|0.325890354 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSDAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4604|beta-lactamase_R241W|0.325890354 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSWGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4605|beta-lactamase_E119W|0.324261151 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRWLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4606|beta-lactamase_F13R|0.323831128 +MSIQHFRVALIPRFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4607|beta-lactamase_W227T|0.322889963 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGTFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4608|beta-lactamase_T27W|0.322758024 +MSIQHFRVALIPFFAAFCLPVFAHPEWLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4609|beta-lactamase_D207P|0.322460917 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIPWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4610|beta-lactamase_Y260Q|0.322399345 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIQTTGSQATMDERNRQIAEIGASLIKHW +>4611|beta-lactamase_R189P|0.321365334 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLPKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4612|beta-lactamase_L247S|0.319592465 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAASGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4613|beta-lactamase_I229Q|0.318813536 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFQADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4614|beta-lactamase_P181M|0.318603411 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMMAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4615|beta-lactamase_T178Y|0.318389376 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDYTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4616|beta-lactamase_M66E|0.318246687 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPEMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4617|beta-lactamase_M67Y|0.318138204 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMYSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4618|beta-lactamase_W227V|0.317270338 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGVFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4619|beta-lactamase_A34D|0.316677101 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDDEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4620|beta-lactamase_P143W|0.316031089 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGWKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4621|beta-lactamase_L146H|0.315709548 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEHTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4622|beta-lactamase_G76H|0.315239455 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCHAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4623|beta-lactamase_W227G|0.314825068 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGGFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4624|beta-lactamase_L192E|0.313913223 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLETGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4625|beta-lactamase_L79G|0.312558649 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVGSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4626|beta-lactamase_D48P|0.312442348 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELPLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4627|beta-lactamase_D177S|0.311147391 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERSTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4628|beta-lactamase_L136G|0.311009588 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLGLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4629|beta-lactamase_L120G|0.308940588 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREGCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4630|beta-lactamase_C121N|0.308623935 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELNSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4631|beta-lactamase_S240R|0.307267406 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGRRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4632|beta-lactamase_L160E|0.306702512 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTREDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4633|beta-lactamase_I278A|0.305045944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEAGASLIKHW +>4634|beta-lactamase_Q203P|0.304961894 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRPQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4635|beta-lactamase_Y44T|0.304629603 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGTIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4636|beta-lactamase_F13E|0.304237695 +MSIQHFRVALIPEFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4637|beta-lactamase_I125Q|0.303085428 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAQTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4638|beta-lactamase_G239Y|0.302561581 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERYSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4639|beta-lactamase_G142M|0.301457203 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGMPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4640|beta-lactamase_I45D|0.30080532600000004 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYDELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4641|beta-lactamase_Y44G|0.30017983800000003 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGGIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4642|beta-lactamase_G248W|0.299384294 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALWPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4643|beta-lactamase_S201E|0.299313927 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAERQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4644|beta-lactamase_G142Y|0.29913019 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGYPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4645|beta-lactamase_I11D|0.297384685 +MSIQHFRVALDPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4646|beta-lactamase_R162W|0.296803176 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDWWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4647|beta-lactamase_I244G|0.296456226 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIGAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4648|beta-lactamase_G216G|0.296109127 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4649|beta-lactamase_T131K|0.296027179 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNKAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4650|beta-lactamase_T178D|0.295853215 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDDTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4651|beta-lactamase_T178K|0.295808258 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDKTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4652|beta-lactamase_D83P|0.295440784 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVPAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4653|beta-lactamase_I229G|0.294343247 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFGADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4654|beta-lactamase_L146N|0.293593638 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKENTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4655|beta-lactamase_I229K|0.29356725 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFKADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4656|beta-lactamase_P65R|0.293551613 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFRMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4657|beta-lactamase_G242Q|0.29345388 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRQIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4658|beta-lactamase_G248R|0.293123544 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALRPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4659|beta-lactamase_T178F|0.292685702 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDFTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4660|beta-lactamase_L150E|0.292516624 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFEHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4661|beta-lactamase_D155S|0.29214915 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGSHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4662|beta-lactamase_I93D|0.292039689 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRDHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4663|beta-lactamase_T178E|0.290916742 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDETMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4664|beta-lactamase_E87P|0.290598133 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQPQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4665|beta-lactamase_I244Y|0.290311777 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIYAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4666|beta-lactamase_M66N|0.290089924 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPNMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4667|beta-lactamase_T69N|0.289935506 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSNFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4668|beta-lactamase_E277P|0.28892690600000004 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAPIGASLIKHW +>4669|beta-lactamase_Y95Q|0.287581128 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHQSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4670|beta-lactamase_R241D|0.287176515 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSDGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4671|beta-lactamase_L205Y|0.286253919 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQYIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4672|beta-lactamase_L120N|0.28516811 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRENCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4673|beta-lactamase_L160W|0.28516811 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRWDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4674|beta-lactamase_D155Q|0.28516811 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGQHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4675|beta-lactamase_T116W|0.28516811 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMWVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4676|beta-lactamase_L100D|0.28516811 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDDVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4677|beta-lactamase_V78K|0.284373544 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAKLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4678|beta-lactamase_V117G|0.284340315 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTGRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4679|beta-lactamase_L55P|0.282760956 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIPESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4680|beta-lactamase_S104Q|0.28179829 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYQPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4681|beta-lactamase_E35Y|0.281548094 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAYDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4682|beta-lactamase_L167R|0.281276398 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPERNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4683|beta-lactamase_G248K|0.28125880600000003 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALKPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4684|beta-lactamase_G236V|0.281193325 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAVERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4685|beta-lactamase_T107F|0.28072616300000003 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVFEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4686|beta-lactamase_E35F|0.28028148 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAFDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4687|beta-lactamase_D83W|0.280024443 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVWAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4688|beta-lactamase_T178R|0.279375498 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDRTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4689|beta-lactamase_T131R|0.27818707 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNRAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4690|beta-lactamase_T69E|0.27818707 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSEFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4691|beta-lactamase_A132T|0.277929056 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTTANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4692|beta-lactamase_C75D|0.277650518 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLDGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4693|beta-lactamase_L167Y|0.277349502 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEYNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4694|beta-lactamase_W227I|0.277190197 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGIFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4695|beta-lactamase_I278W|0.276669283 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEWGASLIKHW +>4696|beta-lactamase_T178H|0.276488477 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDHTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4697|beta-lactamase_L282W|0.276100479 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASWIKHW +>4698|beta-lactamase_D83F|0.275948016 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVFAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4699|beta-lactamase_R162I|0.27430904 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDIWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4700|beta-lactamase_A133N|0.270611816 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTANNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4701|beta-lactamase_I244N|0.270026398 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGINAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4702|beta-lactamase_S104F|0.268879017 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYFPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4703|beta-lactamase_S233L|0.2679789 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKLGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4704|beta-lactamase_R59I|0.265621589 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFIPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4705|beta-lactamase_A185L|0.265046921 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMLTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4706|beta-lactamase_D177A|0.264942348 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERATTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4707|beta-lactamase_F70R|0.264088165 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTRKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4708|beta-lactamase_M1F|0.263449971 +FSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4709|beta-lactamase_A230Q|0.263228118 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIQDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4710|beta-lactamase_L247E|0.262829369 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAEGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4711|beta-lactamase_V72Q|0.262614357 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKQLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4712|beta-lactamase_W286V|0.26236416100000004 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHV +>4713|beta-lactamase_A123K|0.260734959 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSKAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4714|beta-lactamase_W286G|0.260734959 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHG +>4715|beta-lactamase_I229E|0.258924951 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFEADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4716|beta-lactamase_L247Q|0.257522488 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAQGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4717|beta-lactamase_E119V|0.257497078 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRVLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4718|beta-lactamase_M115W|0.253893677 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGWTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4719|beta-lactamase_N272Y|0.253893677 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERYRQIAEIGASLIKHW +>4720|beta-lactamase_G248D|0.253578 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALDPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4721|beta-lactamase_I93G|0.253086405 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRGHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4722|beta-lactamase_G142P|0.249628626 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGPPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4723|beta-lactamase_L74N|0.248518384 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLNCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4724|beta-lactamase_M184G|0.24686768 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAGATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4725|beta-lactamase_L191G|0.246649736 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKGLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4726|beta-lactamase_A230R|0.246161073 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIRDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4727|beta-lactamase_F14E|0.246075068 +MSIQHFRVALIPFEAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4728|beta-lactamase_L146E|0.245907946 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEETAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4729|beta-lactamase_N272F|0.245072332 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERFRQIAEIGASLIKHW +>4730|beta-lactamase_A15R|0.245058649 +MSIQHFRVALIPFFRAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4731|beta-lactamase_T262Q|0.244445866 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTQGSQATMDERNRQIAEIGASLIKHW +>4732|beta-lactamase_D177E|0.244321746 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERETTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4733|beta-lactamase_D155C|0.243282848 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGCHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4734|beta-lactamase_S240P|0.242455053 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGPRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4735|beta-lactamase_M67K|0.242136444 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMKSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4736|beta-lactamase_G234Y|0.240911855 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSYAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4737|beta-lactamase_I256E|0.240744732 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSREVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4738|beta-lactamase_I45W|0.240060604 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYWELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4739|beta-lactamase_G142V|0.239293403 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGVPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4740|beta-lactamase_L223D|0.23887413 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSADPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4741|beta-lactamase_W208G|0.238047312 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDGMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4742|beta-lactamase_G236F|0.237912441 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAFERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4743|beta-lactamase_A133F|0.237878235 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAFNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4744|beta-lactamase_T131I|0.237387617 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNIAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4745|beta-lactamase_N130L|0.237387617 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDLTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4746|beta-lactamase_L74K|0.236301808 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLKCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4747|beta-lactamase_F64H|0.236301808 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERHPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4748|beta-lactamase_C121E|0.234981441 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELESAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4749|beta-lactamase_S233Y|0.233650323 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKYGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4750|beta-lactamase_I229R|0.233372762 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFRADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4751|beta-lactamase_M184N|0.233247664 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAANATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4752|beta-lactamase_L146S|0.23304438 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKESTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4753|beta-lactamase_W286S|0.231559822 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHS +>4754|beta-lactamase_L79W|0.231459158 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVWSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4755|beta-lactamase_V117W|0.230437852 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTWRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4756|beta-lactamase_V117R|0.227916351 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTRRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4757|beta-lactamase_T107Y|0.227416937 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVYEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4758|beta-lactamase_E164H|0.226528548 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWHPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4759|beta-lactamase_I275H|0.225978313 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQHAEIGASLIKHW +>4760|beta-lactamase_F64T|0.22567925100000005 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERTPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4761|beta-lactamase_T187R|0.225480854 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATRLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4762|beta-lactamase_V117K|0.225442738 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTKRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4763|beta-lactamase_P65W|0.223736327 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFWMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4764|beta-lactamase_V78G|0.223549658 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAGLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4765|beta-lactamase_V257N|0.22327112 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRINVIYTTGSQATMDERNRQIAEIGASLIKHW +>4766|beta-lactamase_L167W|0.221564709 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEWNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4767|beta-lactamase_Y95N|0.220444693 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHNSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4768|beta-lactamase_G76Q|0.220012715 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCQAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4769|beta-lactamase_G142F|0.220012715 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGFPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4770|beta-lactamase_I256S|0.218233004 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRSVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4771|beta-lactamase_I259S|0.216904818 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVSYTTGSQATMDERNRQIAEIGASLIKHW +>4772|beta-lactamase_R59V|0.216755287 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFVPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4773|beta-lactamase_G239E|0.216702512 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERESRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4774|beta-lactamase_M115P|0.215726163 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGPTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4775|beta-lactamase_S104W|0.215359666 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYWPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4776|beta-lactamase_F64A|0.214518188 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERAPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4777|beta-lactamase_T69Q|0.212566468 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSQFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4778|beta-lactamase_S233Q|0.21132624100000005 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKQGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4779|beta-lactamase_S128T|0.209459548 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMTDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4780|beta-lactamase_G85P|0.206877453 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAPQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4781|beta-lactamase_T158N|0.20651682 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVNRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4782|beta-lactamase_C18R|0.206351652 +MSIQHFRVALIPFFAAFRLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4783|beta-lactamase_L137K|0.206230463 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLKTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4784|beta-lactamase_M209V|0.205205248 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWVEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4785|beta-lactamase_T107W|0.205205248 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVWEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4786|beta-lactamase_I229D|0.204977531 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFDADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4787|beta-lactamase_T179I|0.204666742 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTIMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4788|beta-lactamase_L79H|0.204564122 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVHSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4789|beta-lactamase_V42Q|0.204249423 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARQGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4790|beta-lactamase_M115D|0.203724599 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGDTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4791|beta-lactamase_G236L|0.203301417 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGALERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4792|beta-lactamase_V42G|0.203274052 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARGGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4793|beta-lactamase_L47D|0.203072723 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEDDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4794|beta-lactamase_G43T|0.202587969 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVTYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4795|beta-lactamase_W286T|0.202022097 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHT +>4796|beta-lactamase_S240K|0.201923387 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGKRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4797|beta-lactamase_S233N|0.201737695 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKNGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4798|beta-lactamase_S68C|0.201063341 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMCTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4799|beta-lactamase_M1W|0.201009588 +WSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4800|beta-lactamase_L192K|0.199652082 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLKTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4801|beta-lactamase_A123R|0.197646609 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSRAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4802|beta-lactamase_G236W|0.196970299 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAWERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4803|beta-lactamase_A245W|0.194658923 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIWALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4804|beta-lactamase_M127P|0.19429438 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITPSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4805|beta-lactamase_M67R|0.193995319 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMRSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4806|beta-lactamase_A245Y|0.19391811 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIYALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4807|beta-lactamase_L137D|0.193543794 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLDTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4808|beta-lactamase_G248Q|0.193019947 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALQPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4809|beta-lactamase_Y95R|0.19214524 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHRSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4810|beta-lactamase_Y44E|0.191658532 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGEIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4811|beta-lactamase_K32P|0.19134481 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVPDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4812|beta-lactamase_G142L|0.190150518 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGLPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4813|beta-lactamase_V31H|0.189656968 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKHKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4814|beta-lactamase_G248F|0.187435506 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALFPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4815|beta-lactamase_E164D|0.187435506 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWDPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4816|beta-lactamase_N272W|0.187435506 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERWRQIAEIGASLIKHW +>4817|beta-lactamase_G239W|0.184704857 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERWSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4818|beta-lactamase_T158H|0.183881949 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVHRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4819|beta-lactamase_L282D|0.181434724 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASDIKHW +>4820|beta-lactamase_Y260H|0.180616703 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIHTTGSQATMDERNRQIAEIGASLIKHW +>4821|beta-lactamase_S240I|0.179447821 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGIRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4822|beta-lactamase_S233F|0.1792289 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKFGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4823|beta-lactamase_L188E|0.178314122 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTERKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4824|beta-lactamase_D177Y|0.178273075 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERYTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4825|beta-lactamase_V258Y|0.17812745300000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVYIYTTGSQATMDERNRQIAEIGASLIKHW +>4826|beta-lactamase_A235W|0.177325068 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGWGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4827|beta-lactamase_E164K|0.17681295 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWKPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4828|beta-lactamase_Y95E|0.176049658 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHESQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4829|beta-lactamase_G236Y|0.175517015 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAYERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4830|beta-lactamase_W208R|0.174896413 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDRMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4831|beta-lactamase_I283D|0.17459441899999995 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLDKHW +>4832|beta-lactamase_V257Q|0.17454750800000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIQVIYTTGSQATMDERNRQIAEIGASLIKHW +>4833|beta-lactamase_S233H|0.174108688 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKHGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4834|beta-lactamase_M1C|0.173955248 +CSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4835|beta-lactamase_M153P|0.172004505 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNPGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4836|beta-lactamase_A280P|0.171587187 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGPSLIKHW +>4837|beta-lactamase_L205S|0.17156470899999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQSIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4838|beta-lactamase_G242V|0.170868853 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRVIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4839|beta-lactamase_G234Q|0.170638204 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSQAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4840|beta-lactamase_I256W|0.169665764 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRWVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4841|beta-lactamase_D177F|0.169665764 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERFTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4842|beta-lactamase_N272P|0.169432183 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERPRQIAEIGASLIKHW +>4843|beta-lactamase_S233R|0.168472449 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKRGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4844|beta-lactamase_L150D|0.168397195 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFDHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4845|beta-lactamase_T187K|0.16815775 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATKLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4846|beta-lactamase_T158Q|0.16758406 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVQRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4847|beta-lactamase_V106P|0.167268384 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPPTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4848|beta-lactamase_T179M|0.16693707 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTMMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4849|beta-lactamase_M1Y|0.165717367 +YSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4850|beta-lactamase_A77P|0.165514083 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGPVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4851|beta-lactamase_V258D|0.165495514 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVDIYTTGSQATMDERNRQIAEIGASLIKHW +>4852|beta-lactamase_D177H|0.165192543 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERHTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4853|beta-lactamase_T131D|0.164166351 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNDAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4854|beta-lactamase_M1N|0.163979681 +NSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4855|beta-lactamase_P65D|0.16384481 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFDMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4856|beta-lactamase_T107D|0.163002355 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVDEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4857|beta-lactamase_L136Q|0.162564513 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLQLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4858|beta-lactamase_T158L|0.161187461 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVLRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4859|beta-lactamase_V72Y|0.159512324 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKYLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4860|beta-lactamase_N130V|0.158867289 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDVTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4861|beta-lactamase_D155A|0.15883112800000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGAHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4862|beta-lactamase_S80P|0.158318032 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLPRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4863|beta-lactamase_G239L|0.158267211 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERLSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4864|beta-lactamase_M1Q|0.158115725 +QSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4865|beta-lactamase_M184K|0.157029916 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAKATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4866|beta-lactamase_D177I|0.156894068 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERITTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4867|beta-lactamase_D155I|0.156572527 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGIHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4868|beta-lactamase_F64S|0.156338946 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERSPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4869|beta-lactamase_M66P|0.155484763 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPPMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4870|beta-lactamase_A276P|0.155157359 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIPEIGASLIKHW +>4871|beta-lactamase_M1K|0.154858297 +KSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4872|beta-lactamase_R162P|0.153229095 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDPWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4873|beta-lactamase_E35W|0.152941761 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAWDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4874|beta-lactamase_R202P|0.152649541 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASPQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4875|beta-lactamase_F70D|0.151896022 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTDKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4876|beta-lactamase_D129E|0.151620416 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSENTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4877|beta-lactamase_I244E|0.1508151 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIEAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4878|beta-lactamase_T262P|0.15078578 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTPGSQATMDERNRQIAEIGASLIKHW +>4879|beta-lactamase_I275Q|0.150673387 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQQAEIGASLIKHW +>4880|beta-lactamase_S104E|0.149755678 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYEPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4881|beta-lactamase_G76N|0.149428274 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCNAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4882|beta-lactamase_T179G|0.149120416 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTGMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4883|beta-lactamase_G248M|0.148342465 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALMPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4884|beta-lactamase_Y95K|0.148027766 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHKSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4885|beta-lactamase_G234N|0.147618266 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSNAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4886|beta-lactamase_V257H|0.147339728 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIHVIYTTGSQATMDERNRQIAEIGASLIKHW +>4887|beta-lactamase_N130E|0.147193129 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDETAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4888|beta-lactamase_W227L|0.146190393 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGLFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4889|beta-lactamase_A230H|0.145550244 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIHDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4890|beta-lactamase_T261D|0.145550244 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYDTGSQATMDERNRQIAEIGASLIKHW +>4891|beta-lactamase_V257G|0.145251183 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIGVIYTTGSQATMDERNRQIAEIGASLIKHW +>4892|beta-lactamase_L247H|0.145195475 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAHGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4893|beta-lactamase_E119I|0.144677492 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRILCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4894|beta-lactamase_D177V|0.143445084 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERVTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4895|beta-lactamase_L136N|0.143370807 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLNLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4896|beta-lactamase_A133H|0.143360057 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAHNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4897|beta-lactamase_W286C|0.143114748 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHC +>4898|beta-lactamase_G248Y|0.142641722 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALYPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4899|beta-lactamase_F64K|0.142328 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERKPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4900|beta-lactamase_T193P|0.142010369 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLPGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4901|beta-lactamase_G236R|0.141378039 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGARERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4902|beta-lactamase_C121F|0.14101252 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELFSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4903|beta-lactamase_S240W|0.140145631 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGWRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4904|beta-lactamase_M1E|0.140145631 +ESIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4905|beta-lactamase_D177Q|0.139889572 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERQTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4906|beta-lactamase_V72N|0.138569204 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKNLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4907|beta-lactamase_L191K|0.13724883699999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKKLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4908|beta-lactamase_R91P|0.13715696800000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGPRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4909|beta-lactamase_V72E|0.137088556 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKELLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4910|beta-lactamase_I275S|0.136953685 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQSAEIGASLIKHW +>4911|beta-lactamase_G236K|0.13608484199999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAKERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4912|beta-lactamase_D177W|0.135694889 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERWTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4913|beta-lactamase_Y95D|0.135395827 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHDSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4914|beta-lactamase_G234F|0.135311777 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSFAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4915|beta-lactamase_M66W|0.135311777 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPWMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4916|beta-lactamase_G242E|0.13439309 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSREIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4917|beta-lactamase_T158Y|0.134127258 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVYRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4918|beta-lactamase_I125G|0.133052199 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAGTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4919|beta-lactamase_G248T|0.132082692 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALTPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4920|beta-lactamase_G279R|0.131861816 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIRASLIKHW +>4921|beta-lactamase_I244Q|0.131730854 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIQAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4922|beta-lactamase_I206P|0.131588165 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLPDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4923|beta-lactamase_I256Q|0.131051613 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRQVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4924|beta-lactamase_I259G|0.130726163 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVGYTTGSQATMDERNRQIAEIGASLIKHW +>4925|beta-lactamase_M1D|0.130425147 +DSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4926|beta-lactamase_M67W|0.12994625699999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMWSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4927|beta-lactamase_G142W|0.12994625699999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGWPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4928|beta-lactamase_L136E|0.12984266 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLELTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4929|beta-lactamase_M1S|0.129172215 +SSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4930|beta-lactamase_G234L|0.128795944 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSLAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4931|beta-lactamase_D155T|0.127710135 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGTHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4932|beta-lactamase_G76E|0.127292817 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCEAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4933|beta-lactamase_S104L|0.126773857 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYLPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4934|beta-lactamase_I125E|0.126650713 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAETMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4935|beta-lactamase_S233K|0.125821941 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKKGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4936|beta-lactamase_L247G|0.124921824 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAGGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4937|beta-lactamase_D177T|0.123751964 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERTTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4938|beta-lactamase_G239P|0.123549658 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERPSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4939|beta-lactamase_G142I|0.122280111 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGIPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4940|beta-lactamase_M184E|0.121465999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAEATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4941|beta-lactamase_Y260N|0.120244341 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVINTTGSQATMDERNRQIAEIGASLIKHW +>4942|beta-lactamase_I45K|0.119520143 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYKELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4943|beta-lactamase_P181N|0.119207398 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMNAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4944|beta-lactamase_I259N|0.119022684 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVNYTTGSQATMDERNRQIAEIGASLIKHW +>4945|beta-lactamase_T107Q|0.119022684 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVQEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4946|beta-lactamase_V31Y|0.118448016 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKYKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4947|beta-lactamase_A124E|0.118076632 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAEITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4948|beta-lactamase_M1A|0.11697714 +ASIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4949|beta-lactamase_E61P|0.116637031 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPPERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4950|beta-lactamase_F64R|0.116357516 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERRPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4951|beta-lactamase_T158D|0.113873153 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVDRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4952|beta-lactamase_D155V|0.113509588 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGVHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4953|beta-lactamase_G234E|0.112822527 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSEAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4954|beta-lactamase_G239V|0.112589924 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERVSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4955|beta-lactamase_L282R|0.112370025 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASRIKHW +>4956|beta-lactamase_I256N|0.111421042 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRNVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4957|beta-lactamase_K71R|0.111421042 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFRVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4958|beta-lactamase_V82P|0.111116116 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRPDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4959|beta-lactamase_V31P|0.11108191 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKPKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4960|beta-lactamase_W208K|0.110878626 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDKMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4961|beta-lactamase_L120E|0.110646022 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREECSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4962|beta-lactamase_D177M|0.10849786 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERMTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4963|beta-lactamase_D155H|0.108027766 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGHHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4964|beta-lactamase_N130I|0.108027766 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDITAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4965|beta-lactamase_L74P|0.107802004 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLPCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4966|beta-lactamase_L150P|0.107327023 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFPHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4967|beta-lactamase_T107E|0.107155014 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVEEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4968|beta-lactamase_Y44S|0.106949775 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGSIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4969|beta-lactamase_M1R|0.106949775 +RSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4970|beta-lactamase_T107R|0.105991996 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVREKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4971|beta-lactamase_L160R|0.105839533 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRRDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4972|beta-lactamase_I275G|0.105612793 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQGAEIGASLIKHW +>4973|beta-lactamase_L73K|0.104739064 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVKLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4974|beta-lactamase_D155P|0.104739064 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGPHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4975|beta-lactamase_C75E|0.103664982 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLEGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4976|beta-lactamase_D177L|0.103664982 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERLTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4977|beta-lactamase_R255W|0.103664982 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSWIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4978|beta-lactamase_Y44D|0.103385467 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGDIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4979|beta-lactamase_K232A|0.103076632 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADASGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4980|beta-lactamase_D177R|0.102647586 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERRTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4981|beta-lactamase_T179L|0.102303567 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTLMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4982|beta-lactamase_N130M|0.101919478 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDMTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4983|beta-lactamase_A245N|0.101793403 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIINALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4984|beta-lactamase_T107H|0.100980268 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVHEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4985|beta-lactamase_A230N|0.100561972 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFINDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4986|beta-lactamase_D155F|0.100561972 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGFHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4987|beta-lactamase_D155M|0.100561972 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGMHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4988|beta-lactamase_V31D|0.099727336 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKDKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4989|beta-lactamase_T178W|0.099264083 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDWTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4990|beta-lactamase_G248V|0.099010956 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALVPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4991|beta-lactamase_G76D|0.098922996 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCDAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4992|beta-lactamase_D155G|0.098770534 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGGHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4993|beta-lactamase_I278Y|0.098587774 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEYGASLIKHW +>4994|beta-lactamase_T107P|0.09820173 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVPEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4995|beta-lactamase_S233E|0.097985741 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKEGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4996|beta-lactamase_L135D|0.097923192 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANDLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4997|beta-lactamase_L205N|0.097846961 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQNIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4998|beta-lactamase_C75Q|0.097220495 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLQGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>4999|beta-lactamase_I243G|0.097115921 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGGIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5000|beta-lactamase_L137R|0.096352629 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLRTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5001|beta-lactamase_A245Q|0.095662637 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIQALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5002|beta-lactamase_W227N|0.095626476 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGNFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5003|beta-lactamase_E164R|0.095451534 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWRPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5004|beta-lactamase_I140P|0.09484657 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTPGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5005|beta-lactamase_D129C|0.094541644 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSCNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5006|beta-lactamase_I244H|0.092368071 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIHAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5007|beta-lactamase_A124D|0.09151291 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSADITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5008|beta-lactamase_K232T|0.09127933 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADTSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5009|beta-lactamase_D129S|0.090491605 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSSNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5010|beta-lactamase_M184W|0.08970290300000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAWATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5011|beta-lactamase_T69F|0.08970290300000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSFFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5012|beta-lactamase_V31Q|0.08970290300000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKQKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5013|beta-lactamase_D177P|0.08970290300000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERPTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5014|beta-lactamase_E164P|0.08970290300000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWPPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5015|beta-lactamase_D155L|0.08970290300000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGLHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5016|beta-lactamase_D155Y|0.08970290300000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGYHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5017|beta-lactamase_L192D|0.08970290300000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLDTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5018|beta-lactamase_L192R|0.08970290300000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLRTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5019|beta-lactamase_F228P|0.08970290300000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWPIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5020|beta-lactamase_E35P|0.08970290300000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAPDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5021|beta-lactamase_D33P|0.08970290300000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKPAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5022|beta-lactamase_C18I|0.08970290300000001 +MSIQHFRVALIPFFAAFILPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5023|beta-lactamase_F13D|0.08970290300000001 +MSIQHFRVALIPDFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5024|beta-lactamase_F14R|0.08970290300000001 +MSIQHFRVALIPFRAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5025|beta-lactamase_M1H|0.08970290300000001 +HSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5026|beta-lactamase_L136H|0.087506851 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLHLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5027|beta-lactamase_G248E|0.08743062 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALEPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5028|beta-lactamase_T107K|0.08743062 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVKEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5029|beta-lactamase_V78D|0.084691175 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGADLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5030|beta-lactamase_I259Q|0.084559236 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVQYTTGSQATMDERNRQIAEIGASLIKHW +>5031|beta-lactamase_A230E|0.08427287900000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIEDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5032|beta-lactamase_L247R|0.084171237 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAARGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5033|beta-lactamase_V31E|0.08411846199999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKEKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5034|beta-lactamase_D177K|0.08411846199999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERKTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5035|beta-lactamase_K232N|0.08366986900000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADNSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5036|beta-lactamase_K232C|0.083397195 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADCSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5037|beta-lactamase_Y44Q|0.082185311 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGQIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5038|beta-lactamase_V31R|0.08172499 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKRKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5039|beta-lactamase_L79R|0.081326241 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVRSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5040|beta-lactamase_N130P|0.080394849 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDPTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5041|beta-lactamase_I275E|0.079306108 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQEAEIGASLIKHW +>5042|beta-lactamase_A230K|0.078843833 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIKDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5043|beta-lactamase_G242D|0.07820466200000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRDIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5044|beta-lactamase_G43F|0.07820466200000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVFYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5045|beta-lactamase_I275N|0.077784412 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQNAEIGASLIKHW +>5046|beta-lactamase_A185Q|0.077735545 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMQTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5047|beta-lactamase_V31K|0.07748632700000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKKKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5048|beta-lactamase_W227Q|0.07748632700000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGQFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5049|beta-lactamase_F149P|0.077092465 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAPLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5050|beta-lactamase_E56P|0.076376085 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILPSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5051|beta-lactamase_A185N|0.075740823 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMNTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5052|beta-lactamase_L205H|0.075740823 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQHIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5053|beta-lactamase_F64E|0.075740823 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEREPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5054|beta-lactamase_L188K|0.073854584 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTKRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5055|beta-lactamase_R255D|0.073793012 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSDIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5056|beta-lactamase_D129N|0.07358191 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSNNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5057|beta-lactamase_C75P|0.07341381 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLPGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5058|beta-lactamase_M209E|0.07341381 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWEEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5059|beta-lactamase_D161P|0.07341381 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLPRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5060|beta-lactamase_L74H|0.07245603 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLHCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5061|beta-lactamase_G239I|0.072160878 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERISRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5062|beta-lactamase_I125D|0.071933161 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAADTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5063|beta-lactamase_L79D|0.071933161 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVDSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5064|beta-lactamase_W227E|0.07160477900000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGEFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5065|beta-lactamase_T69T|0.071564848 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5066|beta-lactamase_P181H|0.071262715 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMHAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5067|beta-lactamase_G279D|0.070156382 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIDASLIKHW +>5068|beta-lactamase_G279K|0.070156382 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIKASLIKHW +>5069|beta-lactamase_L247P|0.068759783 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAPGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5070|beta-lactamase_M209Y|0.067984763 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWYEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5071|beta-lactamase_K232V|0.06736416099999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADVSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5072|beta-lactamase_R81P|0.066974208 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSPVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5073|beta-lactamase_M1P|0.065269752 +PSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5074|beta-lactamase_I256D|0.064482027 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRDVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5075|beta-lactamase_K232S|0.064308063 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADSSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5076|beta-lactamase_V42E|0.063446061 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAREGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5077|beta-lactamase_S233I|0.06339035400000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKIGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5078|beta-lactamase_N130H|0.062742387 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDHTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5079|beta-lactamase_F14D|0.06177972 +MSIQHFRVALIPFDAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5080|beta-lactamase_W227R|0.061057477 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGRFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5081|beta-lactamase_L191D|0.060383122 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKDLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5082|beta-lactamase_V257D|0.059631558 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIDVIYTTGSQATMDERNRQIAEIGASLIKHW +>5083|beta-lactamase_G76P|0.05712569400000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCPAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5084|beta-lactamase_M209N|0.05712569400000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWNEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5085|beta-lactamase_I278S|0.05712569400000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAESGASLIKHW +>5086|beta-lactamase_L188D|0.054519165 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTDRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5087|beta-lactamase_V117D|0.054163419 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTDRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5088|beta-lactamase_T178P|0.053053176 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDPTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5089|beta-lactamase_C75H|0.052113966 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLHGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5090|beta-lactamase_T69K|0.052113966 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSKFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5091|beta-lactamase_I259H|0.05169567 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVHYTTGSQATMDERNRQIAEIGASLIKHW +>5092|beta-lactamase_M209K|0.050609861 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWKEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5093|beta-lactamase_L191R|0.050318618 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKRLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5094|beta-lactamase_T69D|0.049721472 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSDFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5095|beta-lactamase_K232I|0.049563145 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADISGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5096|beta-lactamase_I125Y|0.048980659 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAYTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5097|beta-lactamase_E210P|0.048980659 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMPADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5098|beta-lactamase_L282P|0.046266624000000006 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASPIKHW +>5099|beta-lactamase_M66K|0.045980268 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPKMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5100|beta-lactamase_W227D|0.044909118 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGDFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5101|beta-lactamase_L146P|0.044714631 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEPTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5102|beta-lactamase_M1G|0.044595397 +GSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5103|beta-lactamase_T187P|0.044327609 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATPLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5104|beta-lactamase_L150K|0.043551613 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFKHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5105|beta-lactamase_A133E|0.043408923 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAENLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5106|beta-lactamase_T158P|0.042483395 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVPRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5107|beta-lactamase_C121H|0.040836601 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELHSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5108|beta-lactamase_L120K|0.040836601 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREKCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5109|beta-lactamase_L74D|0.040836601 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLDCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5110|beta-lactamase_W208P|0.040836601 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDPMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5111|beta-lactamase_R59P|0.039583669 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFPPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5112|beta-lactamase_V257K|0.038265256 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIKVIYTTGSQATMDERNRQIAEIGASLIKHW +>5113|beta-lactamase_G43Y|0.036394654 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVYYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5114|beta-lactamase_L136R|0.035720299 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLRLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5115|beta-lactamase_Y260G|0.035638204 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIGTTGSQATMDERNRQIAEIGASLIKHW +>5116|beta-lactamase_L146K|0.034728313 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEKTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5117|beta-lactamase_S68P|0.033382535 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMPTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5118|beta-lactamase_A133I|0.031063341 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAINLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5119|beta-lactamase_Y260E|0.031063341 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIETTGSQATMDERNRQIAEIGASLIKHW +>5120|beta-lactamase_I278Q|0.030214044 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEQGASLIKHW +>5121|beta-lactamase_K232D|0.029977531 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADDSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5122|beta-lactamase_L146R|0.029077414 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKERTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5123|beta-lactamase_K71H|0.028620025 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFHVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5124|beta-lactamase_P181E|0.028620025 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMEAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5125|beta-lactamase_L79K|0.028620025 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVKSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5126|beta-lactamase_A123P|0.028620025 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSPAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5127|beta-lactamase_Y260K|0.027509783 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIKTTGSQATMDERNRQIAEIGASLIKHW +>5128|beta-lactamase_A246P|0.027509783 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAPLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5129|beta-lactamase_N130F|0.027509783 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDFTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5130|beta-lactamase_I256H|0.026874521 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRHVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5131|beta-lactamase_D155R|0.026874521 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGRHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5132|beta-lactamase_G76R|0.025964631 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCRAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5133|beta-lactamase_M66R|0.025905014 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPRMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5134|beta-lactamase_L136F|0.025615725 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLFLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5135|beta-lactamase_M184R|0.025342074 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAARATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5136|beta-lactamase_K232E|0.024547508 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADESGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5137|beta-lactamase_G234R|0.02379008 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSRAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5138|beta-lactamase_G248L|0.02338449 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALLPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5139|beta-lactamase_K232G|0.02213449 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADGSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5140|beta-lactamase_G43L|0.022041644 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVLYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5141|beta-lactamase_T179P|0.020615725 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTPMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5142|beta-lactamase_F70P|0.019894459 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTPKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5143|beta-lactamase_I278D|0.019894459 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEDGASLIKHW +>5144|beta-lactamase_V42K|0.019894459 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARKGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5145|beta-lactamase_G234V|0.019660878 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSVAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5146|beta-lactamase_G43V|0.01959051 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVVYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5147|beta-lactamase_A132V|0.019457594 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTVANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5148|beta-lactamase_G234T|0.018190979 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSTAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5149|beta-lactamase_D129G|0.018148954 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSGNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5150|beta-lactamase_L205G|0.017308453999999997 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQGIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5151|beta-lactamase_A133D|0.017029916000000003 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTADNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5152|beta-lactamase_A185P|0.014526007 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMPTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5153|beta-lactamase_F64G|0.014183943 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERGPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5154|beta-lactamase_I259E|0.013685506000000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVEYTTGSQATMDERNRQIAEIGASLIKHW +>5155|beta-lactamase_I256K|0.012913419 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRKVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5156|beta-lactamase_L247D|0.011515842 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAADGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5157|beta-lactamase_E164M|0.011515842 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWMPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5158|beta-lactamase_S128N|0.011515842 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMNDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5159|beta-lactamase_N134P|0.011515842 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAPLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5160|beta-lactamase_G242R|0.011261738 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRRIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5161|beta-lactamase_S68N|0.010294185 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMNTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5162|beta-lactamase_A235P|0.0100694 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGPGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5163|beta-lactamase_Y44R|0.009971667 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGRIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5164|beta-lactamase_I275D|0.009424365 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQDAEIGASLIKHW +>5165|beta-lactamase_N130R|0.009424365 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDRTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5166|beta-lactamase_I275K|0.008818423 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQKAEIGASLIKHW +>5167|beta-lactamase_Y260D|0.00872069 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIDTTGSQATMDERNRQIAEIGASLIKHW +>5168|beta-lactamase_K71T|0.008261346999999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFTVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5169|beta-lactamase_V72D|0.008261346999999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKDLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5170|beta-lactamase_E164T|0.008261346999999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWTPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5171|beta-lactamase_E164V|0.008261346999999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWVPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5172|beta-lactamase_D129K|0.007606538 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSKNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5173|beta-lactamase_A132E|0.0074013 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTEANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5174|beta-lactamase_G43W|0.0074013 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVWYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5175|beta-lactamase_V42D|0.007010369 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARDGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5176|beta-lactamase_G236P|0.007010369 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAPERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5177|beta-lactamase_S68H|0.006345788000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMHTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5178|beta-lactamase_G76K|0.005935311 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCKAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5179|beta-lactamase_K232H|0.005935311 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADHSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5180|beta-lactamase_K232Q|0.005935311 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADQSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5181|beta-lactamase_K71S|0.005935311 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFSVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5182|beta-lactamase_T179D|0.005935311 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTDMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5183|beta-lactamase_I256R|0.00560302 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRRVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5184|beta-lactamase_K232Y|0.005300049 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADYSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5185|beta-lactamase_A230P|0.005300049 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIPDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5186|beta-lactamase_A124K|0.004997078 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAKITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5187|beta-lactamase_I244K|0.004752746 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIKAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5188|beta-lactamase_C121Y|0.004713653 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELYSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5189|beta-lactamase_S68G|0.004469322 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMGTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5190|beta-lactamase_C121D|0.004185897 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELDSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5191|beta-lactamase_C75K|0.004185897 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLKGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5192|beta-lactamase_I259D|0.004185897 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVDYTTGSQATMDERNRQIAEIGASLIKHW +>5193|beta-lactamase_L79P|0.004185897 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVPSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5194|beta-lactamase_T158E|0.004185897 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVERLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5195|beta-lactamase_S128I|0.004185897 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMIDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5196|beta-lactamase_V257R|0.003140158 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIRVIYTTGSQATMDERNRQIAEIGASLIKHW +>5197|beta-lactamase_L188R|0.003101065 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTRRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5198|beta-lactamase_I278E|0.0028274140000000003 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEEGASLIKHW +>5199|beta-lactamase_V42P|0.0028274140000000003 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARPGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5200|beta-lactamase_Y44N|0.0024462570000000003 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGNIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5201|beta-lactamase_K71N|0.001742582 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFNVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5202|beta-lactamase_P181K|0.001273466 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMKAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5203|beta-lactamase_V42R|0.001273466 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARRGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5204|beta-lactamase_I243K|0.000853215 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGKIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5205|beta-lactamase_T69R|0.000853215 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSRFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5206|beta-lactamase_S128A|0.000853215 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMADNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5207|beta-lactamase_I278K|0.000472058 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEKGASLIKHW +>5208|beta-lactamase_N130K|0.000472058 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDKTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5209|beta-lactamase_L150R|0.000198407 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFRHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5210|beta-lactamase_I244D|-3.620000000000001e-05 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIDAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5211|beta-lactamase_D129A|-0.000251163 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSANTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5212|beta-lactamase_S68L|-0.000309803 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMLTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5213|beta-lactamase_I244P|-0.000407535 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIPAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5214|beta-lactamase_T179R|-0.0007691460000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTRMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5215|beta-lactamase_A133R|-0.000788692 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTARNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5216|beta-lactamase_S68R|-0.000905971 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMRTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5217|beta-lactamase_P181R|-0.000964611 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMRAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5218|beta-lactamase_I244R|-0.00105257 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIRAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5219|beta-lactamase_L205R|-0.00105257 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQRIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5220|beta-lactamase_C75R|-0.001287129 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLRGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5221|beta-lactamase_C75W|-0.0015119139999999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLWGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5222|beta-lactamase_I259K|-0.0015119139999999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVKYTTGSQATMDERNRQIAEIGASLIKHW +>5223|beta-lactamase_M67P|-0.0015119139999999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMPSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5224|beta-lactamase_E164A|-0.0015119139999999998 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWAPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5225|beta-lactamase_I125R|-0.0016878320000000002 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAARTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5226|beta-lactamase_S68A|-0.001726925 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMATFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5227|beta-lactamase_P181D|-0.001922391 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMDAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5228|beta-lactamase_T179K|-0.002020123 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTKMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5229|beta-lactamase_A185E|-0.002284001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMETTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5230|beta-lactamase_T179N|-0.002284001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTNMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5231|beta-lactamase_L188P|-0.002440373 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTPRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5232|beta-lactamase_L135P|-0.002440373 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANPLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5233|beta-lactamase_A185D|-0.002596746 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMDTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5234|beta-lactamase_S68T|-0.002596746 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMTTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5235|beta-lactamase_V78R|-0.002792211 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGARLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5236|beta-lactamase_L247K|-0.002889943 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAKGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5237|beta-lactamase_T158K|-0.002889943 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVKRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5238|beta-lactamase_L136P|-0.0030854090000000003 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLPLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5239|beta-lactamase_L136D|-0.003144048 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLDLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5240|beta-lactamase_G43D|-0.003378606 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVDYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5241|beta-lactamase_W227K|-0.003378606 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGKFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5242|beta-lactamase_G242I|-0.003486112 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRIIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5243|beta-lactamase_A245D|-0.003583845 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIDALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5244|beta-lactamase_S68D|-0.003583845 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMDTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5245|beta-lactamase_V72R|-0.00377931 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKRLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5246|beta-lactamase_S68V|-0.00377931 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMVTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5247|beta-lactamase_T179H|-0.003955229 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTHMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5248|beta-lactamase_A230D|-0.004043188 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIDDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5249|beta-lactamase_G43R|-0.004267973 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVRYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5250|beta-lactamase_S128R|-0.0043461590000000005 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMRDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5251|beta-lactamase_G43E|-0.004414572 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVEYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5252|beta-lactamase_G242Y|-0.004473211 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRYIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5253|beta-lactamase_T179E|-0.004473211 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTEMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5254|beta-lactamase_A124R|-0.004776183 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSARITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5255|beta-lactamase_A132R|-0.004776183 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTRANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5256|beta-lactamase_I243P|-0.004776183 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGPIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5257|beta-lactamase_L47P|-0.004776183 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEPDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5258|beta-lactamase_A245R|-0.004844595 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIRALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5259|beta-lactamase_I259R|-0.004873915 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVRYTTGSQATMDERNRQIAEIGASLIKHW +>5260|beta-lactamase_L137P|-0.004913008 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLPTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5261|beta-lactamase_A245K|-0.004971648 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIKALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5262|beta-lactamase_T158R|-0.00506938 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVRRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5263|beta-lactamase_L191P|-0.00515734 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKPLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5264|beta-lactamase_I278R|-0.005235526 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAERGASLIKHW +>5265|beta-lactamase_P181Y|-0.005753509 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMYAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5266|beta-lactamase_D129R|-0.005782828 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSRNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5267|beta-lactamase_D129H|-0.005909881 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSHNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5268|beta-lactamase_A245E|-0.00599784 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIEALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5269|beta-lactamase_A245P|-0.006036933 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIPALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5270|beta-lactamase_D129V|-0.006036933 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSVNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5271|beta-lactamase_D129L|-0.006183531999999999 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSLNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5272|beta-lactamase_K232L|-0.006251945 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADLSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5273|beta-lactamase_T179Q|-0.006427864 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTQMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5274|beta-lactamase_I243R|-0.00644741 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGRIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5275|beta-lactamase_G242P|-0.006730835 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRPIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5276|beta-lactamase_L73R|-0.006809021 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVRLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5277|beta-lactamase_G242L|-0.007356323 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRLIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5278|beta-lactamase_A124F|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAFITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5279|beta-lactamase_A124H|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAHITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5280|beta-lactamase_A124P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAPITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5281|beta-lactamase_A124Y|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAYITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5282|beta-lactamase_A132K|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTKANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5283|beta-lactamase_A132L|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTLANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5284|beta-lactamase_A132M|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTMANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5285|beta-lactamase_A132P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTPANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5286|beta-lactamase_A133L|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTALNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5287|beta-lactamase_A133Q|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAQNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5288|beta-lactamase_A185K|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMKTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5289|beta-lactamase_A185R|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMRTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5290|beta-lactamase_A185Y|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMYTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5291|beta-lactamase_A245H|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIHALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5292|beta-lactamase_C121K|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELKSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5293|beta-lactamase_C121P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELPSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5294|beta-lactamase_C121R|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELRSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5295|beta-lactamase_C121W|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELWSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5296|beta-lactamase_C75Y|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLYGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5297|beta-lactamase_D129F|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSFNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5298|beta-lactamase_D129I|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSINTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5299|beta-lactamase_D129M|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSMNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5300|beta-lactamase_D129P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSPNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5301|beta-lactamase_D129Q|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSQNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5302|beta-lactamase_D129T|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSTNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5303|beta-lactamase_D129W|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSWNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5304|beta-lactamase_D129Y|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSYNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5305|beta-lactamase_G242F|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRFIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5306|beta-lactamase_G242K|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRKIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5307|beta-lactamase_G242W|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRWIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5308|beta-lactamase_G248P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALPPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5309|beta-lactamase_G43I|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVIYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5310|beta-lactamase_G43K|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVKYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5311|beta-lactamase_G43M|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVMYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5312|beta-lactamase_G43N|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVNYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5313|beta-lactamase_I125K|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAKTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5314|beta-lactamase_I125P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAPTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5315|beta-lactamase_I125W|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAWTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5316|beta-lactamase_I244W|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIWAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5317|beta-lactamase_I256P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRPVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5318|beta-lactamase_I259P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVPYTTGSQATMDERNRQIAEIGASLIKHW +>5319|beta-lactamase_I45P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYPELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5320|beta-lactamase_K232F|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADFSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5321|beta-lactamase_K232M|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADMSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5322|beta-lactamase_K232P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADPSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5323|beta-lactamase_K232W|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADWSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5324|beta-lactamase_K71E|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFEVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5325|beta-lactamase_K71I|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFIVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5326|beta-lactamase_K71P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFPVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5327|beta-lactamase_K71Y|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFYVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5328|beta-lactamase_L120D|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREDCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5329|beta-lactamase_L120R|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRERCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5330|beta-lactamase_L120W|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREWCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5331|beta-lactamase_L136K|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLKLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5332|beta-lactamase_L136W|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLWLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5333|beta-lactamase_L136Y|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLYLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5334|beta-lactamase_L205D|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQDIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5335|beta-lactamase_L205K|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQKIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5336|beta-lactamase_L74R|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLRCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5337|beta-lactamase_M184D|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAADATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5338|beta-lactamase_M184P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAPATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5339|beta-lactamase_M209R|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWREADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5340|beta-lactamase_P181F|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMFAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5341|beta-lactamase_P181Q|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMQAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5342|beta-lactamase_P181W|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMWAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5343|beta-lactamase_T179F|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTFMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5344|beta-lactamase_T179W|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTWMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5345|beta-lactamase_T179Y|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTYMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5346|beta-lactamase_T69W|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSWFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5347|beta-lactamase_V257P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIPVIYTTGSQATMDERNRQIAEIGASLIKHW +>5348|beta-lactamase_V258R|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVRIYTTGSQATMDERNRQIAEIGASLIKHW +>5349|beta-lactamase_V72K|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKKLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5350|beta-lactamase_V78P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAPLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5351|beta-lactamase_Y260P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIPTTGSQATMDERNRQIAEIGASLIKHW +>5352|beta-lactamase_Y260R|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIRTTGSQATMDERNRQIAEIGASLIKHW +>5353|beta-lactamase_Y44K|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGKIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5354|beta-lactamase_Y44P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGPIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5355|beta-lactamase_F64D|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERDPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5356|beta-lactamase_L146D|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEDTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5357|beta-lactamase_E164F|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWFPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5358|beta-lactamase_E164G|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWGPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5359|beta-lactamase_E164N|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWNPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5360|beta-lactamase_E164S|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWSPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5361|beta-lactamase_G234D|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSDAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5362|beta-lactamase_G234I|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSIAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5363|beta-lactamase_G234K|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSKAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5364|beta-lactamase_G234P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSPAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5365|beta-lactamase_G234W|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSWAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5366|beta-lactamase_I275P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQPAEIGASLIKHW +>5367|beta-lactamase_I275R|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQRAEIGASLIKHW +>5368|beta-lactamase_I278G|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEGGASLIKHW +>5369|beta-lactamase_I278H|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEHGASLIKHW +>5370|beta-lactamase_I278N|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAENGASLIKHW +>5371|beta-lactamase_I278P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEPGASLIKHW +>5372|beta-lactamase_M66D|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPDMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5373|beta-lactamase_S233D|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKDGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5374|beta-lactamase_S68E|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMETFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5375|beta-lactamase_S68F|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMFTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5376|beta-lactamase_S68I|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMITFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5377|beta-lactamase_S68K|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMKTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5378|beta-lactamase_S68M|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMMTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5379|beta-lactamase_S68Q|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMQTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5380|beta-lactamase_S68W|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMWTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5381|beta-lactamase_S68Y|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMYTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5382|beta-lactamase_S128C|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMCDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5383|beta-lactamase_S128D|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMDDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5384|beta-lactamase_S128H|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMHDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5385|beta-lactamase_S128K|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMKDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5386|beta-lactamase_S128L|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMLDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5387|beta-lactamase_S128Q|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMQDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5388|beta-lactamase_S128V|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMVDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5389|beta-lactamase_S128W|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMWDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5390|beta-lactamase_S128Y|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMYDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5391|beta-lactamase_I229P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFPADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5392|beta-lactamase_N130W|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDWTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5393|beta-lactamase_R241P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSPGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5394|beta-lactamase_R255P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSPIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5395|beta-lactamase_W227P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGPFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW +>5396|beta-lactamase_R159P|-0.008030678000000001 +MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTPLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW \ No newline at end of file diff --git a/esm/source/examples/data/UniRef50_E9K9Y4.a3m b/esm/source/examples/data/UniRef50_E9K9Y4.a3m new file mode 100644 index 0000000000000000000000000000000000000000..e06c5dac5792609735b5a885e2adee2f4b0e7538 --- /dev/null +++ b/esm/source/examples/data/UniRef50_E9K9Y4.a3m @@ -0,0 +1,34 @@ +>UniRef50_E9K9Y4 +MADNVLMAYHIVHDPDERAKHVLNTKKLYKWRITEKTKGTPVVGNVALVQTQFAKRTPVMIYATKEVANDLSDLQPVKVFTNNRDQETVNQTFDDLMR +>tr|A0A161UNY6|A0A161UNY6_LACCL Uncharacterized protein OS=Lactobacillus collinoides GN=TY91_01215 PE=4 SV=1 +MADNILMAYHIVLDPNDRTKHVLNTKKLYKWRITDKTKGTPVIGNVALVKTKFSKRVPVMIYATKEVTNDLSNLQPVKIFTTNRDQEAVNKAFDNLLK +>tr|A0A165PM23|A0A165PM23_LACPN LtrC-like protein OS=Lactobacillus plantarum GN=Nizo2891_2777 PE=4 SV=1 +MADNVLMAYHIVHDPDERAKHVLNTKKLYKWRITEQTKGTPVIGYVAT----WAKDKAVIHSAL---------------------------------- +>tr|X0PKM7|X0PKM7_9LACO Uncharacterized protein OS=Lactobacillus farraginis DSM 18382 = JCM 14108 GN=FD41_GL001280 PE=4 SV=1 +LADNVLMALHIIGNSKD-PKPHLNTNHFYKWRIDADTEGTPKIGNLAKVETQFGIQ-HVVIWGTKEVAQDISDMKRVIKFDD---------------- +>tr|A0A221N0Z6|A0A221N0Z6_LACSK Uncharacterized protein OS=Lactobacillus sakei GN=B4V05_10130 PE=4 SV=1 +--KQLIQGLHLVRDPENPKLVSLNTDKVYVWQITHQTKGTPKVGNLAVVETKKGQQ------------------------------------------ +>tr|G9ZNW5|G9ZNW5_9LACO Uncharacterized protein OS=Lactobacillus parafarraginis F0439 GN=HMPREF9103_01419 PE=4 SV=1 +---LVIGAIHIRLED--GGKRVLQTDQEFFWRITERTtnegaplqDGFPELGRVAVVPTKYGWR-PVVVVQEQRVTGeaaikAADDLKRVRRFTAND-------------- +>tr|A0A0R1W220|A0A0R1W220_9LACO Uncharacterized protein OS=Lactobacillus farraginis DSM 18382 = JCM 14108 GN=FD41_GL002732 PE=4 SV=1 +---RVIGGLHLRLEE--NGKRSLSTDQEFFWEIGKYTdnegdrlvDGFPELGRIAVVETKYGWR-PVVVVREQTVTGeaavkAADELKYVRRFTKND-------------- +>tr|C2D001|C2D001_LACBR Uncharacterized protein OS=Lactobacillus brevis subsp. gravesensis ATCC 27305 GN=HMPREF0496_0873 PE=4 SV=1 +---RVIGGLHIRLEE--DGKRTLATDHEFFWKIGKKTgnegselvDGFPELGRVAVVETKFGWR-PVLVVREQTVTGeaavkAADDLRHVSRFTAND-------------- +>tr|A0A166GPA0|A0A166GPA0_LACCL Uncharacterized protein OS=Lactobacillus collinoides GN=TY91_09755 PE=4 SV=1 +-PTNIIGALHINVDDN--GQQHLNTEKIFYWRLGMYTKnatsgkkttVLPALGTIASVFTQFGRQ-DVMVVQTFQSGIDQasqtqvSHLRRVFTTSDAG-------------- +>tr|A0A0R2EPJ1|A0A0R2EPJ1_9LACO Uncharacterized protein OS=Lactobacillus similis DSM 23365 = JCM 2765 GN=FD14_GL002086 PE=4 SV=1 +-SRRVISAVHLNKDEA--GELTLNLTHEYQWRTGAHTYfangepaqnTEPTVGTIAIAKTYRGDK-RVVIVDSTFVAKEVvspneliqaNRLRRITQYTDEK-------------- +>tr|A0A1Y2KRT9|A0A1Y2KRT9_LACPA Uncharacterized protein OS=Lactobacillus paracasei GN=B9J76_08465 PE=4 SV=1 +---QVLLARHFKESPDDHHLHL--VPHIYRWGITSDTTGEPQRGKIAKVQTKSGVQ-EVIVLKVKEQSPRRrpYVYQPVISFESY--------------- +>tr|A0A023D133|A0A023D133_9LACO Uncharacterized protein OS=Lactobacillus sucicola DSM 21376 = JCM 15457 GN=FD15_GL002287 PE=4 SV=1 +MPRIVIAGFHIEDDPE--KGKVLNTKKKYYWRVSAHTEnkkvdGkniEFKKGHLADVLTYRGPQ-KVFIIGVCiaeqeEVKEWAKKLQRVLKYHLE--------------- +>tr|A0A0F4KQ37|A0A0F4KQ37_9LACO Uncharacterized protein OS=Lactobacillus mellis GN=JG29_16320 PE=4 SV=1 +MVRRAVEVMHLNRNQE-TGKYYLS-HKGYFFQISSHTKdskvkkfyGrMIPLGQIVKVQTNYGWK-PAVVVKNMEVTGDFalkavKRLKRVTRITDQKL------------- +>tr|N9WER6|N9WER6_9CLOT Uncharacterized protein OS=Clostridium colicanis 209318 GN=HMPREF1092_02059 PE=4 SV=1 +---NVIKGMHFGTDE--NGNMILNNDKAFHWRIPNALTGKVNKGDMVIVRVKtkSGAikHVPVLVIDVINNFENTEnlNLKNIVR------------------- +>tr|B1BYI7|B1BYI7_CLOPF Uncharacterized protein OS=Clostridium perfringens E str. JGS1987 GN=AC3_A0261 PE=4 SV=1 +---MFIEAMHIYKf-K--DGRIKLKTSGKYIWAIPKRLEEeNISLGDIVLVPCK---knNAPVIVLNVFENNNKKFgyKHKKVIK------------------- +>tr|A0A1C6L357|A0A1C6L357_9CLOT Uncharacterised protein OS=uncultured Clostridium sp. GN=SAMEA3545266_03736 PE=4 SV=1 +---KVIEGFHIKKiqrgTK--KGQDYINHNKRYVWKIPERLEGQIEKGDIVWVHAKKDNkdiKARVLVVDVLENNDGA--LRSVIK------------------- +>tr|A0A1C6L2U1|A0A1C6L2U1_9CLOT Uncharacterised protein OS=uncultured Clostridium sp. GN=SAMEA3545266_03712 PE=4 SV=1 +---KFIEGFFIKKytrgTK--KGKEYIKTKKRYVWSIPKELENEIQVADEVLVETSwlKDGkyisgKTKVLVLNVFEKDEDQEERKKVLK------------------- diff --git a/esm/source/examples/data/UniRef50_UPI0003108055.a3m b/esm/source/examples/data/UniRef50_UPI0003108055.a3m new file mode 100644 index 0000000000000000000000000000000000000000..99984872e15ea3d91467fd30986c6b8c71890780 --- /dev/null +++ b/esm/source/examples/data/UniRef50_UPI0003108055.a3m @@ -0,0 +1,2078 @@ +>UniRef50_UPI0003108055 +MPADAREYLESKHATRRFDRPAEVAGVVAFLLSDDTSFVIGAGYLVDGGYTALRAARGRLGPRRQAAPAVKLLPNTDSPR +>tr|A0A1U7CY72|A0A1U7CY72_9BACT 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Paludisphaera borealis GN=fabG_9 PE=4 SV=1 +----G--RPDFPTGIKNLTTPDDIGAAVVYLSSPAGRKTTGDILYIDSGLHCAD-------------------------- +>tr|A0A1U8CPL0|A0A1U8CPL0_MESAU 3-hydroxybutyrate dehydrogenase type 2 isoform X2 OS=Mesocricetus auratus GN=Bdh2 PE=3 SV=1 +-PKEGHRHASHIsYPEVSLATGSAS-----FPKPTEDRKVcvcrrSGPALRVPGLG------------------------------ +>tr|E2CEN7|E2CEN7_9RHOB Short-chain dehydrogenase/reductase SDR OS=Roseibium sp. TrichSKD4 GN=TRICHSKD4_1510 PE=3 SV=1 +--PVSQLDPSAHIPA------EWVGEAISWLSTDAGDAYKGTDCSLRDESVR---------------------------- +>tr|A0A0M1WAH7|A0A0M1WAH7_BRUAO Glucose 1-dehydrogenase II OS=Brucella abortus NCTC 8038 GN=BAUG_2384 PE=3 SV=1 +---Q---ALVALHPMGgvlagprRLQTPSCSSQATKLPSSTVHRFWSTAAIPPNNAKTP---------------------------- +>tr|F0XW91|F0XW91_AURAN Putative uncharacterized protein (Fragment) OS=Aureococcus anophagefferens GN=AURANDRAFT_14129 PE=3 SV=1 +-------SKKTVAMFGGLMTPEHVTDALFDKVVDEPNAEAVLRITpLEGVAF----------------------------- +>tr|A0A1K1TLC4|A0A1K1TLC4_PANAN 3-oxoacyl-[acyl-carrier protein] reductase OS=Pantoea ananas GN=SAMN03097714_0328 PE=4 SV=1 +-LTSYREQRIRKIPGKKIGDPEQCAMLAALLCSPAMFYLTGQSINIDGGYT----------------------------- +>tr|A0A1F4WI25|A0A1F4WI25_9BACT Uncharacterized protein OS=candidate division WWE3 bacterium RIFOXYC1_FULL_39_7 GN=A2415_00365 PE=4 SV=1 +-PERTAKLIIKQIENGRNGEYFEPiAMVIRLLAMSRGLI------------------------------------------ +>tr|A0A0D2H5D7|A0A0D2H5D7_9EURO Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.3, whole genome shotgun sequence OS=Rhinocladiella ma +----------QKTPFQRGADPAELAKAISYFLVTSPHFRPDLSWSLTVDFWL---------------------------- +>tr|A0A072P414|A0A072P414_9EURO Uncharacterized protein OS=Exophiala aquamarina CBS 119918 GN=A1O9_09266 PE=4 SV=1 +VPESIREGWRKANVLGRLAEPVEMANVIHFLLSDKSSFITSSVRLGRSKTDCLKT------------------------- +>tr|A0A0F9JU37|A0A0F9JU37_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_1716490 PE=4 SV=1 +---AQRDAMVGQMP---LIPPREMAEAVLEFVRDDSL--AGEAMGVMYGRPH---------------------------- +>tr|K1ZEB3|K1ZEB3_9ZZZZ Short chain dehydrogenase (Fragment) OS=groundwater metagenome GN=ACD_73C00042G0001 PE=4 SV=1 +-------------FFKTNTKPNDVARVIKFLCEEGLkGSMSGSVFPLftNG-------------------------------- +>tr|A0A1C3NDW3|A0A1C3NDW3_9ACTN Meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase OS=Micromonospora krabiensis GN=GA0070620_6 +--------------TPPAIPATEIADAVATLLT--DDTLAGRVLVCqakeprrlllpADGWSDHV-------------------------- +>tr|A0A199YQF9|A0A199YQF9_9LACT 3-ketoacyl-ACP reductase OS=Lactococcus lactis RTB018 GN=V425_10045 PE=3 SV=1 +------ETYGQNIPDEwKMGSSSDVANF--IINDLIESEMTGKIFSVNGSeigYWQEP-------------------------- +>tr|A0A1Y2B8R8|A0A1Y2B8R8_9FUNG NAD(P)-binding protein OS=Rhizoclosmatium globosum GN=BCR33DRAFT_857106 PE=3 SV=1 +--------EASSVPVSLV--------IDAFMRAIEDESLAGDILRVtsq-KGID--V-------------------------- +>tr|A0A078AM39|A0A078AM39_STYLE Cylg protein OS=Stylonychia lemnae GN=Contig11717.g12535 PE=4 SV=1 +-KLLQL-QNKQEINPKLFGQPSQISSIVATMCSEDGGFVNGETYFMQGVLG----------------------------- +>tr|A0A1M2IDY6|A0A1M2IDY6_ECOLX 3-ketoacyl-ACP reductase (Fragment) OS=Escherichia coli GN=BK384_28395 PE=4 SV=1 +-TAYYDeLIAKGLVPWGRWGYPADIASTVRAMAEGKLIYTCGQAVAIDGGLS----------------------------- +>tr|L8WJT2|L8WJT2_THACA Short chain dehydrogenase domain-containing protein OS=Thanatephorus cucumeris (strain AG1-IA) GN=AG1IA_07788 PE=4 SV=1 +--QEMQKVWLERTPLKRMASPAEIGKSVAFLVPHSERIVNLyDRVGAIGGWRI---------------------------- +>tr|A0YDC0|A0YDC0_9GAMM Short-chain dehydrogenase/reductase SDR OS=marine gamma proteobacterium HTCC2143 GN=GP2143_03843 PE=4 SV=1 +---TAMPDVEQGRKDMGIGEPDDIAHMVTYLISDASKHINGAQIVIDNADTV---------------------------- +>tr|A0A1W9QF96|A0A1W9QF96_9DELT Uncharacterized protein OS=Sorangiineae bacterium NIC37A_2 GN=B6A08_06105 PE=4 SV=1 +-------PLQGISFLSRIVKCEETRAAIVFLASEASRQLHGKTVIAARAAED---------------------------- +>tr|A0A1F6GGP0|A0A1F6GGP0_9PROT Uncharacterized protein OS=Candidatus Lambdaproteobacteria bacterium RIFOXYD2_FULL_50_16 GN=A2527_10530 PE=4 SV=1 +-------SPEDYIPQGRFGEYSDLWPVFDLIFRADSTYQTGNNFVISGGYAL---------------------------- +>tr|A0A1N6DZN8|A0A1N6DZN8_9RHOB 3-oxoacyl-[acyl-carrier protein] reductase OS=Oceanicola litoreus GN=SAMN05444002_0181 PE=4 SV=1 +---TKDALFRSWTADGEVTTVDEIGTLAVFLLSDAGAALNGSEVVADRAMSAL--------------------------- +>tr|A0A1G1HT84|A0A1G1HT84_9BACT Uncharacterized protein OS=Nitrospirae bacterium RIFCSPHIGHO2_02_FULL_42_12 GN=A3D21_01415 PE=4 SV=1 +LPESVKDKIVSSNILNREQDMAEVVEFIYNLSK--MNNVSGQIFNLDSRIL----------------------------- +>tr|A0A1S2V5K2|A0A1S2V5K2_9PSED Uncharacterized protein OS=Pseudomonas costantinii GN=BFL40_07335 PE=4 SV=1 +-----spvmFEPILNSASLGAMGTSGDVARVVCGLLQPGYIQ--ATTIKVDGGHLR---------------------------- +>tr|A0A0K2MEP9|A0A0K2MEP9_CLOBE Uncharacterized protein OS=Clostridium beijerinckii NRRL B-598 GN=X276_15185 PE=4 SV=1 +LDNSVLCEILKSTPHARFAKMSEISEMVCQLFNPKINYITGQTIVVDGGRYMI--------------------------- +>tr|L5KKQ3|L5KKQ3_PTEAL L-xylulose reductase OS=Pteropus alecto GN=PAL_GLEAN10014507 PE=3 SV=1 +---QKAKTILARIPLGRFAEVSEVVDTILFLLRAADHRLQGACgwgLPHQLSPSPTT-------------------------- +>tr|A0A1Q4F453|A0A1Q4F453_9SPHI Uncharacterized protein OS=Sphingobacteriales bacterium 44-15 GN=BGP14_17035 PE=4 SV=1 +---TEDphgwikHYIEHEQVIPRAVDPLDCGYVAAFLLSGLSRSVTGQTIYIDNGDTIKL-------------------------- +>tr|A0A226EH58|A0A226EH58_FOLCA Carbonyl reductase [NADPH] 2 OS=Folsomia candida GN=Fcan01_09343 PE=4 SV=1 +---TFKAFLKFRTPTQTaHMPTDECINTMLFLMSDLTTQITGHNLTIDGGYLCT--------------------------- +>tr|A0A226D458|A0A226D458_FOLCA D-erythrulose reductase OS=Folsomia candida GN=Fcan01_26175 PE=4 SV=1 +---ISRTPLPGVCPEGNfMMGMDQVVESVLFLLSPRTAGaTTGQQLFVDNGYSVG--------------------------- +>tr|A0A0Q7ZSF3|A0A0Q7ZSF3_9ACTN Uncharacterized protein OS=Nocardioides sp. Root151 GN=ASD66_00625 PE=4 SV=1 +-----RLIHPWG--QEESATADDMAAVIAFAASDEARYWNASELRLDGGARASF-------------------------- +>tr|A0A1E3HA04|A0A1E3HA04_9TREE Uncharacterized protein OS=Cryptococcus amylolentus CBS 6039 GN=L202_07743 PE=4 SV=1 +-----YGGQEKLNPLQRQGFAFEIAHMTLFLVSVPVSPF----------------------------------------- +>tr|A0A1P8ND03|A0A1P8ND03_9MICO Uncharacterized protein OS=Brachybacterium sp. P6-10-X1 GN=BH708_05105 PE=4 SV=1 +--------------------DPDEVGTMILDAIHHGRLYCQPDRLMAEpiqarCQALLEA------------------------- +>tr|A0A1Q9E1T1|A0A1Q9E1T1_SYMMI 15-hydroxyprostaglandin dehydrogenase [NAD(+)] OS=Symbiodinium microadriaticum GN=Hpgd PE=4 SV=1 +---------ANHPLLKDQLLPEEVADAYIALIENDKLNSQAAAIMPQVS--YLHN------------------------- +>tr|A0A1C5K599|A0A1C5K599_9ACTN NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Micromonospora inositola GN=GA0070613_6415 PE=4 SV= +----FEQRAARNNVMGRPNDPQEVAEAIAWVLSDEARTVSGTVLEVGTLPRYSN-------------------------- +>tr|A0A1J5R2C0|A0A1J5R2C0_9ZZZZ 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=mine drainage metagenome GN=fabG_51 PE=4 SV=1 +---AYLRRLlanYPQGEHARFLTPQEVAHHVVWLLSPACAGVTGAQVMLDFGLTAG--------------------------- +>tr|A0A1R0LL84|A0A1R0LL84_9ACTN Uncharacterized protein OS=Streptomyces sp. IMTB 2501 GN=AV521_28565 PE=4 SV=1 +-------------QLQDMMRPHDVAEAIVYALAQPRTM-RTLLWSMRSAASEN--------------------------- +>tr|A0A1M7R430|A0A1M7R430_9ACTN 3-oxoacyl-[acyl-carrier protein] reductase OS=Cryptosporangium aurantiacum GN=SAMN05443668_106384 PE=4 SV=1 +---GNADDIVAGLAVPRVGTSRELYEAIVYFCGDAAGWVTGQTLRVDGGGGLR--------------------------- +>tr|A0A1C5AWR1|A0A1C5AWR1_9ACTN NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Micromonospora carbonacea GN=GA0070563_12350 PE=4 S +----GTDGGRIAAVEAALGRPEDVASVLVLLASPVSAGLAGTVCTG---------------------------------- +>tr|A0A1X4NFX8|A0A1X4NFX8_9PROT Short-chain dehydrogenase OS=Thalassospira sp. MCCC 1A01428 GN=THS27_02760 PE=4 SV=1 +--DDWLTKAEAEQPFGKLVKPDEVAGLAAYLLAAESGVMTGAIIDYDQYVSG---------------------------- +>tr|C7DH70|C7DH70_MICA2 Short-chain dehydrogenase/reductase SDR OS=Candidatus Micrarchaeum acidiphilum ARMAN-2 GN=UNLARM2_0416 PE=4 SV=1 +----------RSEMGSQEQRPEDLAGIAEWLLGEESVLVDGVVIQADSGYRFARR------------------------- +>tr|A0A1B1MQ33|A0A1B1MQ33_STRLN 3-oxoacyl-ACP reductase OS=Streptomyces lincolnensis GN=SLINC_8497 PE=4 SV=1 +----RESMLVRQTALGRAGDPVDVAELGFYLCSKPGGYVTSQILQINGGSQHGV-------------------------- +>tr|A0A158GRJ6|A0A158GRJ6_9BURK 3-alpha-hydroxysteroid dehydrogenase OS=Caballeronia udeis GN=AWB69_03121 PE=4 SV=1 +----FEKSFVDLTPLGRITRPEDIAAMTYMLVRD-EFFETGQIFNYSGGNSLLGH------------------------- +>tr|A0A0F0F9Q7|A0A0F0F9Q7_9PSED Uncharacterized protein OS=Pseudomonas sp. 2(2015) GN=UB48_14530 PE=4 SV=1 +---QAAAA----ILKGCFRRQFRINlssDVKLlilvqkLLPQKLSTYVIDRVLPFPPV------------------------------- +>tr|A0A1F0I4X2|A0A1F0I4X2_9PSED Short-chain dehydrogenase OS=Pseudomonas sp. HMSC065H01 GN=HMPREF3014_00575 PE=4 SV=1 +---SVTRSINQRLVDGSFLSPGEIVDVVMFLLSSKSAGLYGQELIVDKGYGLR--------------------------- +>tr|A0A1H2FG99|A0A1H2FG99_9PSED NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Pseudomonas pohangensis GN=SAMN05216296_1542 PE=4 S +---QLAGQLGRRLLPGHFVDAAAVAQVIAFQLSQGARGVYGQDWVVDNGYSLRQG------------------------- +>tr|A0A1L7X994|A0A1L7X994_9HELO Related to estradiol 17-beta-dehydrogenase 8 OS=Phialocephala subalpina GN=PAC_11496 PE=4 SV=1 +---EAMEEQTKGVAMGRFGTAEEVADVVIFLFIGFEAVKKKVVIIQ---------------------------------- +>tr|A0A1S8GNY2|A0A1S8GNY2_9PROT Uncharacterized protein OS=Bombella intestini GN=AL01_07520 PE=4 SV=1 +---VLKAVADANPSKRSFSTPEDIAAVVQFLAGPGAVALHGSAIVVDEGTSLGLV------------------------- +>tr|K5B7B5|K5B7B5_MYCHD Short chain dehydrogenase family protein OS=Mycobacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 / 3849) GN=C731_ +---AQLAELMqavalaGGPLINRRAHVDEVANLLLFLAGPSGRSLSGAVIPFDGGFTAK--------------------------- +>tr|L1PWV9|L1PWV9_ANAHA Putative sorbitol-6-phosphate 2-dehydrogenase OS=Anaerostipes hadrus DSM 3319 GN=HMPREF0369_02185 PE=4 SV=1 +----VLPYFKKNIPMHKLVDLQDVIQAAIFLLTDCs-SYLTGQSINLVGGEWM---------------------------- +>tr|A0A1J5E0Q0|A0A1J5E0Q0_9BACT Uncharacterized protein OS=Candidatus Desantisbacteria bacterium CG2_30_40_21 GN=AUJ95_02305 PE=4 SV=1 +----KE----QAKKMSVLHKLSSLDETASFIV--Nl-SQMTgisGQVFSLDSRVCG---------------------------- +>tr|A0A0R1SAY5|A0A0R1SAY5_9LACO Short-chain alcohol dehydrogenase OS=Lactobacillus versmoldensis DSM 14857 = KCTC 3814 GN=FC27_GL000768 PE=3 SV=1 +--------AMQANYDQYQIGPDRVANVVAFAIDQPEDTNVSE-------FTV---------------------------- +>tr|A0A1J9S3Y1|A0A1J9S3Y1_9PEZI 3-ketoacyl-acp reductase OS=Diplodia corticola GN=BKCO1_2300094 PE=4 SV=1 +-----QETQEAQ--TALAKLPEDVAKMVIQLATEESGWMAGNSVSVDGGNST---------------------------- +>tr|A0A1C5WSM7|A0A1C5WSM7_9CLOT Glucose 1-dehydrogenase OS=uncultured Clostridium sp. GN=SAMEA3545293_02424 PE=3 SV=1 +----MMVAKLDEIPT-----ADSVAIVVYGMCTRMADGVTGECIVADSGMMR---------------------------- +>tr|A0A1G3KXJ1|A0A1G3KXJ1_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWB1_36_13 GN=A2Y41_06235 PE=4 SV=1 +----------KDVHIQRLIEPEEITGLMKVAA--ENDALDATTLEITGGVLY---------------------------- +>tr|A0A1G5C7A8|A0A1G5C7A8_9RHIZ Short chain dehydrogenase OS=Rhizobium sp. NFACC06-2 GN=SAMN03159288_00835 PE=4 SV=1 +-ARPPLke-------ERAVMMDPHDVDRAILLCASLNKSAVIPElhicpthmrdtskDIEVARWVGAP--------------------------- +>tr|A0A1I2U7Q0|A0A1I2U7Q0_9ACTN Short chain dehydrogenase OS=Streptomyces mirabilis GN=SAMN02787118_126103 PE=4 SV=1 +-AARELIVGIDDQPIPRLADVDEVSSPVLFVATDDAGYSTGAEFVAGGGYLLG--------------------------- +>tr|A0A1Q7PQ18|A0A1Q7PQ18_9BACT Uncharacterized protein OS=Nitrospirae bacterium 13_1_40CM_2_62_10 GN=AUI21_01715 PE=4 SV=1 +-YPS--------EDPGRLRAPSVAADALLRLAMCTSPSISGKAFDLENLP------------------------------ +>tr|A0A1K1RKR0|A0A1K1RKR0_9BACT 3-oxoacyl-[acyl-carrier protein] reductase OS=Chitinophaga sancti GN=SAMN05661012_03950 PE=3 SV=1 +LPDQYISNRVGNSLLKRMGTTDEISNFISYLALECPEFLINQEIVIDGGMN----------------------------- +>tr|A0A1J9SYR2|A0A1J9SYR2_9BACI 3-oxoacyl-ACP reductase OS=Bacillus sp. N35-10-4 GN=BAU26_18970 PE=3 SV=1 +VPDNKLSNFLHHTNTKALGQTEQIANIVMFLADDENSYFTSTVFKIDGGFL----------------------------- +>tr|A0A1Q4P028|A0A1Q4P028_SERMA Uncharacterized protein OS=Serratia marcescens GN=BHU62_11465 PE=3 SV=1 +LPESTYSHVLQVSAIKRTGCVKDVSSIVQLLCGDHCNYMTGQVIHIDGGKF----------------------------- +>tr|A0A1N6Y2D0|A0A1N6Y2D0_9SPIO 3-oxoacyl-[acyl-carrier protein] reductase OS=Alkalispirochaeta americana GN=SAMN05920897_1374 PE=3 SV=1 +VNESRTTKAFS---NEWNKNPEDVIPLLNFMLSFDETGPTGQTFSLTRREI----------------------------- +>tr|H3F7K4|H3F7K4_PRIPA Uncharacterized protein OS=Pristionchus pacificus GN=WBGene00107707 PE=4 SV=1 +----KSgeeni-ISNSEIMLGRLGVPEEIGGIQ-FIPGNSRVrhHIDHHDLLhtddADASIHG---------------------------- +>tr|A0A1F4ZJP3|A0A1F4ZJP3_9BACT Uncharacterized protein OS=Candidatus Amesbacteria bacterium RIFOXYB1_FULL_47_13 GN=A2379_02410 PE=3 SV=1 +----NKagdem--YTKAIKQKktGGDSPELAARLVSFLISNKANHISGCLLSakwdKKGELSD---------------------------- +>tr|R5IDX5|R5IDX5_9FIRM Uncharacterized protein OS=Firmicutes bacterium CAG:124 GN=BN480_01486 PE=4 SV=1 +---RYVTEYGAGVPV--APNPDEIARMILTLCTPVSDFMYGQTVEVDGGSQFS--------------------------- +>tr|A0A1L9P202|A0A1L9P202_9RHOB 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Planktotalea frisia GN=fabG_2 PE=4 SV=1 +---EVLANAIAQMPHGHAMQPEQIAGWVSFLAGPMGDVSSGNVFILNQGRDVR--------------------------- +>tr|A0A172X7A5|A0A172X7A5_9MICO Sugar dehydrogenase OS=Leifsonia xyli GN=A0130_13150 PE=4 SV=1 +------QKLENSIPLRTVADPSQIGDVVAFVISDGGSYLTATTVFVDGGIMHGSVG------------------------ +>tr|A0A1D2MF22|A0A1D2MF22_ORCCI L-xylulose reductase OS=Orchesella cincta GN=Ocin01_15092 PE=3 SV=1 +------ERFMQETVIK---RPIEKRNCRLGFCSF---------------------------------------------- +>tr|A0A1T5EPX8|A0A1T5EPX8_9SPHN 2-deoxy-D-gluconate 3-dehydrogenase OS=Sphingomonas histidinilytica GN=SAMN06295920_107130 PE=3 SV=1 +------ELVAKGLPPktnreLGYYPPDELAAVAVWLASEGAAMVNGRMLHASGPELQIWRM------------------------ +>tr|A0A061PFF3|A0A061PFF3_9VIBR 2-deoxy-D-gluconate 3-dehydrogenase OS=Vibrio sp. JCM 19053 GN=JCM19053_1001 PE=4 SV=1 +----LWDHIRKEQMRQNFTQPEEIADVVAFLVSEKATVSTVVPSAHLTVSRILS-------------------------- +>tr|A0A1U9KJS5|A0A1U9KJS5_ACEAC 3-oxoacyl-ACP reductase OS=Acetobacter aceti GN=A0U92_15805 PE=4 SV=1 +---NA-RRAMASLPTGQPGSPVTVARMVAELARPDAGSITGSIIDINCGLYMR--------------------------- +>tr|A0A1S8AVY7|A0A1S8AVY7_9EURY Dehydrogenase OS=Haloterrigena saccharevitans GN=A6E15_07960 PE=3 SV=1 +---DAAALLAAQGSDGVTGESMT---------AE--EWEDRLA------------------------------------- +>tr|M3C9S3|M3C9S3_SPHMS NAD(P)-binding protein OS=Sphaerulina musiva (strain SO2202) GN=SEPMUDRAFT_53690 PE=4 SV=1 +----VKGKLLEKHPFRGLGKTEDLAKVAVFLASEDVQWVTGVSVEVFFSLSF---------------------------- +>tr|F2I1K7|F2I1K7_PELSM D-beta-hydroxybutyrate dehydrogenase OS=Pelagibacter sp. (strain IMCC9063) GN=SAR11G3_01246 PE=4 SV=1 +--LDARVEmLRDKQPSLKFVRKEDIASMIFFLCSQEADQVTGSNISLDGAWTA---------------------------- +>tr|A0A1S1QRA1|A0A1S1QRA1_9ACTN Uncharacterized protein OS=Frankia sp. Cc1.17 GN=CC117_20560 PE=4 SV=1 +---FYPAWMAKGYVNSDFLDVDEIVRVIANLLENRAGtSipsitITARSIAASS-------------------------------- +>tr|A0A192IJ83|A0A192IJ83_9RHIZ Uncharacterized protein OS=Rhizobiales bacterium NRL2 GN=TEF_11135 PE=3 SV=1 +-----------------------VYPTAKWLAAFAADDMTGRVFWNRQEYRIFDEAN----------------------- +>tr|A0A1F7F211|A0A1F7F211_9BACT Uncharacterized protein OS=Candidatus Raymondbacteria bacterium RIFOXYD12_FULL_49_13 GN=A2519_20130 PE=3 SV=1 +-------------GESLFGSVSDVHAAaRFILMLAQSEWSTGAIYDFDSRVYN----G----------------------- +>tr|A0A212F0Y3|A0A212F0Y3_DANPL 3-oxoacyl OS=Danaus plexippus plexippus GN=KGM_201625 PE=4 SV=1 +------QNMANQVPLKELVRAEKIAEVAALIASDRGSTITGCDYIIDSGMSLKR-------------------------- +>tr|V5H9M8|V5H9M8_IXORI Putative mitochondrial/plastidial beta-ketoacyl-acp reductase OS=Ixodes ricinus PE=2 SV=1 +---EQREMIVAQVPLGRAAQPREGGRCRCFSLLA-rELVHD-WSRD----------------------------------- +>tr|A0A1V4PSZ3|A0A1V4PSZ3_9MYCO Uncharacterized protein OS=Mycobacterium sp. AT1 GN=B1790_13295 PE=4 SV=1 +------DDAFVGADFP-VLSSHDVAHHVLNLLSPANRGINGTSVVCDFGYMAR--------------------------- +>tr|A0A242AUI5|A0A242AUI5_9ENTE Uncharacterized protein OS=Enterococcus sp. 7F3_DIV0205 GN=A5821_000204 PE=4 SV=1 +-FPDIRPNYKKSVQFPYLGKAADIANGIIYLACDEASFVTGAELVIDGERVAL--------------------------- +>tr|A0A225MRC7|A0A225MRC7_9BURK 3-oxoacyl-ACP reductase OS=Candidimonas nitroreducens GN=CEY11_06395 PE=4 SV=1 +------DIKAAADVLGKAAMPDEIAQTILFLAGTGGAYTTGQILGTRIRYGQ---------------------------- +>tr|F0JRD0|F0JRD0_ESCFE Putative uncharacterized protein OS=Escherichia fergusonii ECD227 GN=ECD227_2756 PE=4 SV=1 +-------QPYIGSVAGRAVNGEDMMATIRFLLSDEAQAISGTIIDIGCFFHQGSST------------------------ +>tr|A0A1G1PZX2|A0A1G1PZX2_9BACT Uncharacterized protein OS=Omnitrophica WOR_2 bacterium RIFOXYA2_FULL_38_17 GN=A2243_04790 PE=3 SV=1 +----------------RLMTPDAVVDMVMFALSVpQNACPLELAVINQ----QTPWI------------------------ +>tr|A0A0K2R3S2|A0A0K2R3S2_9MICC Gluconate 5-dehydrogenase OS=Arthrobacter sp. Hiyo4 GN=AHiyo4_28800 PE=4 SV=1 +----FNAWILGRTPAHRWGTVQDLAGRRCGWPR------TGRIL------------------------------------ +>tr|A0A1V6J951|A0A1V6J951_9BACT Diacetyl reductase ((S)-acetoin forming) OS=Bacteroidetes bacterium ADurb.Bin012 GN=butA PE=4 SV=1 +------------LGVDEAFDPEELAEFISDFAEYGFEFFNGKILPVSVTTP----------------------------- +>tr|A0A0D2BH62|A0A0D2BH62_9EURO Uncharacterized protein OS=Exophiala spinifera GN=PV08_05150 PE=4 SV=1 +----------RFTPMGRLGTAQEIADVATFLGQPTSLARSLPLMVairLNsveiyTNAIG---------------------------- +>tr|A0A0F4YJ54|A0A0F4YJ54_TALEM Uncharacterized protein OS=Rasamsonia emersonii CBS 393.64 GN=T310_8148 PE=4 SV=1 +----------SIAPMNSTSLMQTEwAPWMRWltafysyAAAKQHLFK--ALLSls--TGDTG---------------------------- +>tr|A0A137QDQ1|A0A137QDQ1_9AGAR 3-oxoacyl-[acyl-carrier-protein] reductase FabG (Fragment) OS=Leucoagaricus sp. SymC.cos GN=AN958_11464 PE=4 SV=1 +------GKLGQLIPLGCFGAPECVLQHPFP-PAdthpnateiaqaglfialDNSSYVNGQKFAVDGGVSSS--------------------------- +>tr|A0A0Q8QFX3|A0A0Q8QFX3_9BURK Short-chain dehydrogenase OS=Noviherbaspirillum sp. Root189 GN=ASE07_04755 PE=3 SV=1 +------DINTLQDPVnvakAVksvLLLPEQTVIPEIMVLPmQESSW-P---------------------------------------- +>tr|B9X9R2|B9X9R2_PEDPL Short-chain dehydrogenase/reductase SDR OS=Pedosphaera parvula (strain Ellin514) GN=Cflav_PD5845 PE=3 SV=1 +-------HDYLQ-PEdvae-----------TVLYLARlSPAAW-PTEIVIdRKGAAL----------------------------- +>tr|U5BUD3|U5BUD3_9BACT Short-chain dehydrogenase OS=Rhodonellum psychrophilum GCM71 = DSM 17998 GN=P872_15775 PE=3 SV=1 +------DAWKIQ-SEdlgq-----------MVVDLMQmHPRTL-PSKIEVrPSMPG------------------------------ +>tr|A0A1V2PWN6|A0A1V2PWN6_9PSEU Uncharacterized protein OS=Saccharothrix sp. ALI-22-I GN=ALI22I_44740 PE=3 SV=1 +---------------------DTAAPGLVDLIDRLGPDDHGACVLPDGSHYD---------------------------- +>tr|A0A1Q6SZQ7|A0A1Q6SZQ7_9PROT Uncharacterized protein OS=Acetobacter sp. 46_36 GN=BHW56_06990 PE=4 SV=1 +---DDKEAQKRRLPSRRLGQPAEVAALVYNIITNHYAFTSGQCFNFDGGAFL---------------------------- +>tr|A0A1D2MUQ4|A0A1D2MUQ4_ORCCI 3-hydroxybutyrate dehydrogenase type 2 OS=Orchesella cincta GN=Ocin01_10226 PE=4 SV=1 +-PEKARADFIARQKMGRIGTAAEIAALALYLACPESDFVLVKRELVSIvRWYVA--------------------------- +>tr|Q39YI1|Q39YI1_GEOMG Oxidoreductase, putative OS=Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) GN=Gmet_0450 PE=4 SV=1 +----RAASILAHTPTKRFATVEGVVESAIALCIPQ-RHLTGNVIFCDDGYVIEG-------------------------- +>tr|A0A1Y5GWT3|A0A1Y5GWT3_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium 45_16_T64 GN=A9Q99_09710 PE=3 SV=1 +----NLDVLAGGLP--MMLSPQRVATAALkgmrknkaiipvgmdsYLPYLANRYAPGIYDMIL---SRGV-------------------------- +>tr|A0A0M4LMI8|A0A0M4LMI8_9MICC Short-chain dehydrogenase OS=Arthrobacter sp. ERGS1:01 GN=AL755_17635 PE=3 SV=1 +-----ARQLRELVDSGDp-TSP-----RFCSLGETDLAW------------------------------------------ +>tr|A0A1D2N1Z2|A0A1D2N1Z2_ORCCI L-xylulose reductase OS=Orchesella cincta GN=Ocin01_07401 PE=3 SV=1 +-----SRTPMTGSDDHPi-IPMDDVVNTILFMSSDLCGMLSGENVVLDGGFCA---------------------------- +>tr|D2VUA9|D2VUA9_NAEGR Predicted protein OS=Naegleria gruberi GN=NAEGRDRAFT_72596 PE=4 SV=1 +----YKN-FVNLHENKELESPEKIGEILACLVDR-------FPMEWSGQ------------------------------- +>tr|A0A0N0PE07|A0A0N0PE07_PAPMA Putative oxidoreductase OS=Papilio machaon GN=RR48_01529 PE=3 SV=1 +----YVYNNLIAELGLKkILEPKEVAKLVLLVASNl-MPNMAGSSLKMDGAVIGIR-------------------------- +>tr|A0A150TPZ5|A0A150TPZ5_SORCE 3-oxoacyl-ACP reductase OS=Sorangium cellulosum GN=BE21_33090 PE=3 SV=1 +-------GYRPPG--HNPQSPEEVAEGIVRAVEArRDVWETSLF-VKTASLAARV-------------------------- +>tr|A0A1E5T508|A0A1E5T508_9BACT Short chain dehydrogenase OS=Fabibacter misakiensis GN=BFP71_01870 PE=3 SV=1 +-------QGSSPRDEGKMMTAEEVALGIIKAIRKrKRDIV---F-TTQGK----L-------------------------- +>tr|A0A1E4EZD1|A0A1E4EZD1_9BACT Uncharacterized protein OS=bacterium SCN 62-11 GN=ABS71_14580 PE=3 SV=1 +----------RQKVDELLVEPSEIVDIVVEFIQDd-SLVGEARFIGKSGLPPEGK-------------------------- +>tr|A0A1F3M913|A0A1F3M913_9BACT Short chain dehydrogenase OS=Bacteroidetes bacterium GWF2_41_31 GN=A2W85_06525 PE=3 SV=1 +----DENsmmtaeevALHLYKAIGRRKNKIIL-------------TKQGKLTNLINK------------------------------- +>tr|A0A1V0N4C1|A0A1V0N4C1_9EURY 3-ketoacyl-(Acyl-carrier-protein) reductase OS=Ferroplasma acidiphilum GN=FAD_1114 PE=4 SV=1 +-------FSKKFTLTGKLIDPDEVADTVLYLIRNe-SMTGQVITIDSGGEQMATD-------------------------- +>tr|A0A0D0GD63|A0A0D0GD63_9SPHI Contig109, whole genome shotgun sequence OS=Pedobacter lusitanus GN=TH53_21650 PE=3 SV=1 +-------SIDTAAAKMRQLQPADIAETIVFAVTRpDHVLISELL-IRPLDQ------------------------------ +>tr|A0A1E5GCF2|A0A1E5GCF2_9ENTE Uncharacterized protein OS=Enterococcus ureasiticus GN=BCR21_13440 PE=4 SV=1 +QSHKFVEANDRSI-LKKNTQQRDLNNFLLFFISDKIEGVTGQSFNIDDRNF----------------------------- +>sp|P19871|3BHD_COMTE 3-beta-hydroxysteroid dehydrogenase OS=Comamonas testosteroni PE=1 SV=5 +------LHDPKLNRAGRAYMPERIAQLVLFLASDESSVMSGSELHADNSILGM--------------------------- +>tr|A0A090MFR3|A0A090MFR3_9BACT Uncultured bacterium genome assembly Metasoil_fosmids_resub OS=uncultured bacterium PE=3 SV=1 +--------------AGPVSDPVLVAKRVRELVDLPDLPGRGEDyla------------------------------------- +>tr|A0A1Q7UHQ9|A0A1Q7UHQ9_9ACTN Uncharacterized protein OS=Actinobacteria bacterium 13_1_20CM_4_69_9 GN=AUG91_04610 PE=4 SV=1 +---------------DEMIRPEDCAEVVRMCtrLSPTARVPQ----VVMERMGSA--------------------------- +>tr|F6F3Z4|F6F3Z4_SPHCR 3-oxoacyl-(Acyl-carrier-protein) reductase OS=Sphingobium chlorophenolicum L-1 GN=Sphch_3566 PE=3 SV=1 +-Pl-LWNKPMAQP---RMTALPAHVAALVVWLCTDAASHVSGRDFYIQGDEV----------------------------- +>tr|A0A1J5FPF5|A0A1J5FPF5_9BACT Uncharacterized protein OS=Candidatus Moranbacteria bacterium CG2_30_45_14 GN=AUK19_02125 PE=4 SV=1 +-Pe-GMLDREVGFIYMSRQGEPIEVAKFITGVMTDACSYVTGTTFKIDGGYP----------------------------- +>tr|A0A223N792|A0A223N792_ENTFL NAD(P)-dependent oxidoreductase OS=Enterococcus faecalis GN=ADH73_05570 PE=4 SV=1 +-Eq-AENELYKNINCQSRLGNVKDVSNMVDFLVSEKSSYLNGEDISLNGGYK----------------------------- +>tr|A0A0K9QBK2|A0A0K9QBK2_SPIOL Uncharacterized protein (Fragment) OS=Spinacia oleracea GN=SOVF_197780 PE=4 SV=1 +-----ENSpWKDRGDGGGVRIGGVFMHACGFIHY----------------------------------------------- +>tr|A0A0G4F1K4|A0A0G4F1K4_9ALVE Uncharacterized protein OS=Chromera velia CCMP2878 GN=Cvel_14665 PE=3 SV=1 +----MKKLVRSTGPL---LEVSKVAGALVDLIMDETA--HGRVLRVsnesgvsvqrypdDIGFRP---------------------------- +>tr|B5JNB0|B5JNB0_9BACT Oxidoreductase, short chain dehydrogenase/reductase family OS=Verrucomicrobiae bacterium DG1235 GN=VDG1235_3508 PE=3 SV=1 +----AWSSIDDI---CKLVAN-LSSGSY---S-----ALSGRFIHVnddlq--QLA----------------------------- +>tr|S3I3R7|S3I3R7_9RHIZ Short-chain dehydrogenase/reductase SDR OS=Rhizobium grahamii CCGE 502 GN=RGCCGE502_31342 PE=3 SV=1 +----YLPGIQKLFDDGVNVEPSRAARLIADIASGRYDALAGRLLRGIDDRD----------------------------- +>tr|G2IKR8|G2IKR8_9SPHN Short-chain dehydrogenase/reductase SDR OS=Sphingobium sp. SYK-6 GN=SLG_27950 PE=3 SV=1 +----LVALLESTTAEESAQGMARLRRFVVALAAGEHDAMAGRYLDIEKDIP----------------------------- +>tr|A0A101Q1B4|A0A101Q1B4_STRAT Short-chain dehydrogenase OS=Streptomyces antibioticus GN=AQJ23_31805 PE=3 SV=1 +----VDGLVEA----SGALAAEDLADVVAYVTG-LPRHVNLRQIMV---------------------------------- +>tr|A0A0P0SKX2|A0A0P0SKX2_9PSEU Uncharacterized protein OS=Pseudonocardia sp. EC080619-01 GN=AD017_27730 PE=3 SV=1 +----YTE-----RLATVGLDPAVVADGIVHVLASPAQ-------VVEYALT----------------------------- +>tr|A0A1E4B7Z4|A0A1E4B7Z4_9BACT Uncharacterized protein OS=Gemmatimonadetes bacterium SCN 70-22 GN=ABS52_11355 PE=3 SV=1 +-------DVRAVMM-----RSEEVADVIVFMASLPPN-------VRIDDIV----------------------------- +>tr|A0A1D8SZR1|A0A1D8SZR1_9ACTN Uncharacterized protein OS=Streptomyces pactum GN=BC342_34110 PE=4 SV=1 +----YARFVRN-HEEGGLITPEQSARALVGRMGGNAS-------GQIWDVS----------------------------- +>tr|A0A0C2VC56|A0A0C2VC56_9BACL Uncharacterized protein OS=Paenibacillus sp. VKM B-2647 GN=SD70_05770 PE=4 SV=1 +---QAKDEVLRHVPQRRFIHPDEIAFAVLFLSSPLAQGISALDLSIDNGLANT--------------------------- +>tr|F3P8A9|F3P8A9_9ACTO Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Actinomyces sp. oral taxon 170 str. F0386 GN=HMPREF9056_0 +---QKAERITNTdmfmHDPVSILSPEDVADCVSFLFSEKSIRITGQRLVVSGKYEYK--------------------------- +>tr|A0A0W0Z5W7|A0A0W0Z5W7_LEGSP Short-chain dehydrogenases/reductases family protein OS=Legionella spiritensis GN=Lspi_1304 PE=4 SV=1 +---EFYKSRINKVPIREFGDPHNIAKTALFMVSPVNHYMNGSIVLVDGGITSL--------------------------- +>tr|B7RWL7|B7RWL7_9GAMM Oxidoreductase, short chain dehydrogenase/reductase family OS=marine gamma proteobacterium HTCC2148 GN=GPB2148_1699 PE=3 SV=1 +---GIEAWRDSGTYMNVGMETEQVGEAVAFALSQPAGVAIDL-LELRPKRLMK--------------------------- +>tr|K1LA32|K1LA32_9BACT 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Cecembia lonarensis LW9 GN=fabG_5 PE=4 SV=1 +---DKQDAVLERQYMG-LLQPSNLVNACIFLLSESSCFINGTSFPADGGYLQ---------------------------- +>tr|A0A094R2H2|A0A094R2H2_9ZZZZ Uncharacterized protein OS=freshwater metagenome GN=GM51_3570 PE=4 SV=1 +---GGEESMKSQLVMGELVKPSELGELVVFLSSGACRHLTGSTIDVNGASYIR--------------------------- +>tr|A0A193FL05|A0A193FL05_9BORD Short-chain dehydrogenase OS=Bordetella bronchialis GN=BAU06_20965 PE=4 SV=1 +------------IDPGVLQDPANVARAVRFVLMQPEETVVPE-VMVLPMRETS--------------------------- +>tr|A0A101N3A2|A0A101N3A2_9ACTN Short-chain dehydrogenase OS=Streptomyces cellostaticus GN=AQI88_41600 PE=3 SV=1 +------------LPDRDFLSAEQLGETIVWAIGQPRGIDINT-VIVRPIGQSV--------------------------- +>tr|A0A1M3DC20|A0A1M3DC20_9SPHN Uncharacterized protein OS=Sphingomonas sp. 67-36 GN=BGO24_15050 PE=3 SV=1 +---ALDARIAGMTPMAMAPQAEDIAGPIEMLLDPAGRAITGEVWRVDAGAHLD--------------------------- +>tr|A0A222EAU8|A0A222EAU8_9RHOB 3-ketoacyl-ACP reductase OS=Antarctobacter heliothermus GN=ANTHELSMS3_04924 PE=4 SV=1 +------------TPKAERLQPDDVAAIVSLVLALPNQASVPE-IVANTRLESM--------------------------- +>tr|A0A1U6HGZ5|A0A1U6HGZ5_9SPHN NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Novosphingobium mathurense GN=SAMN06295987_102383 P +---IVEAEFTADIPTGSILDVEAVGRLVTFIATAPNAAVTGQSLTVDGGYSR---------------------------- +>tr|A0A034UJ91|A0A034UJ91_9NOCA Putative oxidoreductase OS=Nocardia brasiliensis NBRC 14402 GN=NBRGN_072_00480 PE=4 SV=1 +------GELRPGEVSQGDSGPAEVAEAIRFLASRRAAHVHGALLTMNGEAGAA--------------------------- +>tr|A1UP20|A1UP20_MYCSK Short-chain dehydrogenase/reductase SDR OS=Mycobacterium sp. (strain KMS) GN=Mkms_5392 PE=3 SV=1 +---F-IDDVAGALPLGRTARPRGGRSGGAVPDVAAVEFRDGVDAVRRrrrLGGVTR--------------------------- +>tr|A0A225MRL1|A0A225MRL1_9BURK Uncharacterized protein OS=Candidimonas nitroreducens GN=CEY11_06380 PE=4 SV=1 +---DVLKSIAARKF--APLTPEDVADAVMYAVTTRaGCCPDLIELRPTEN------------------------------- +>tr|A0A1J5HSZ5|A0A1J5HSZ5_9PORP Sugar dehydrogenase OS=Porphyromonadaceae bacterium CG2_30_38_12 GN=AUK44_00940 PE=4 SV=1 +---EALNDLMKLIPYKRIGQTADIGAVAVWLVTDEADYIHGASIYVDGGMTLYPG------------------------- +>tr|A0A0F9KCE3|A0A0F9KCE3_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=LCGC14_1421800 PE=4 SV=1 +-----KSKFLKQVPLGRVISERSWRAALRFAIE--CEDFAGAQVLIDGGYTA---------------------------- +>tr|X1M172|X1M172_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S06H3_25955 PE=4 SV=1 +--ESPWMDRKFAFVLEKAPSPDDVAPFINYLASEEAAGINGKVFNIGGSIIN---------------------------- +>tr|F0YDM1|F0YDM1_AURAN Putative uncharacterized protein OS=Aureococcus anophagefferens GN=AURANDRAFT_28663 PE=4 SV=1 +-PAAARAAGDRAQVMGRMGTILEAGRLCLCIAAD-MTFTTGVDHILSGGAEIGYAM------------------------ +>tr|L2GAY2|L2GAY2_COLGN 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase OS=Colletotrichum gloeosporioides (strain Nara gc5) GN=CGGC5_4737 PE=4 S +-GGTFTPtAQTIPQLIKRMAEPEEIAASICFLLGDESKFVTRSEWRVDGGWLEGSLT------------------------ +>tr|A0A090DKU5|A0A090DKU5_MESPL Short-chain dehydrogenase/reductase SDR OS=Mesorhizobium plurifarium GN=MPL3356_110096 PE=4 SV=1 +-LEEWMPFFLHNISMHTMIDMKEIADVAVFLASDLAPHISGQSISVCGNFESYRGP------------------------ +>tr|A0A1D2TZ48|A0A1D2TZ48_9SPHN 3-oxoacyl-[acyl-carrier-protein] reductase OS=Sphingobium sp. SCN 64-10 GN=ABS86_02905 PE=3 SV=1 +-IEEETALGLASQSLKRIVPPEHVADLAHFLTTPAGRSMSGAALPIDCDLQHG--------------------------- +>tr|A0A1Q4FE96|A0A1Q4FE96_9SPHI Short-chain dehydrogenase OS=Sphingobacteriales bacterium 44-15 GN=BGP14_23140 PE=4 SV=1 +-KNAAEEYINNIHPLGYCPGGDVIAEACVFLMSDKARFITGCTMPVSGGAELGYRR------------------------ +>tr|A0A077Z3V4|A0A077Z3V4_TRITR Adh short domain containing protein OS=Trichuris trichiura GN=TTRE_0000262801 PE=3 SV=1 +--------LMNADSNNRLIILPRQSNGHTIVAYD---------FLPSN-------------------------------- +>tr|A0A1Y3E807|A0A1Y3E807_9BILA Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Trichinella nativa GN=D917_00057 PE=3 SV=1 +-----------VTSSRSTCSINDYAEIVLHLLSDNAHSLPSGVYAADENCTL---------------------------- +>tr|A0A1F7R0N5|A0A1F7R0N5_9BACT Uncharacterized protein OS=Candidatus Saccharibacteria bacterium RIFCSPHIGHO2_12_FULL_47_16b GN=A3F65_00605 PE=4 SV=1 +LTAEQWQTLLEMMPDKKALQPEDIASAIAEV---LISNKTGQVVVVDGGLSE---------------------------- +>tr|A0A1T4X9K5|A0A1T4X9K5_9BACT 3-oxoacyl-[acyl-carrier protein] reductase OS=Prosthecobacter debontii GN=SAMN02745166_01271 PE=4 SV=1 +LLAKHRPEVESRHTLGRLNTAEDAARFIAFLHTL--ENVSGQVFQLDSRIHR---------------------------- +>tr|A0A1V3ZWP6|A0A1V3ZWP6_RHORH Short-chain dehydrogenase (Fragment) OS=Rhodococcus rhodochrous GN=GQ85_04420 PE=4 SV=1 +IKDR--------IPAEEMLEVNDVVELVDAVLRLSSRAVLPRLVLSRAGTDA---------------------------- +>tr|A0A0I9RIL1|A0A0I9RIL1_KLEVA 3-hydroxybutyrate dehydrogenase OS=Klebsiella variicola GN=bdhA PE=3 SV=1 +----SAQLLAEKPALRGVCHPAATGrngAVSVQRCR-----CPGARRRMEYGWRL---------------------------- +>tr|A0A1V5ZBF5|A0A1V5ZBF5_9BACT Glucose 1-dehydrogenase 4 OS=Candidatus Latescibacteria bacterium ADurb.Bin168 GN=gdhIV PE=4 SV=1 +-------WDKRAK-----PVAHDAAELAAFLCSEAGRFVSQSLIRYpTDGW------------------------------ +>tr|W6YC77|W6YC77_COCCA Uncharacterized protein OS=Bipolaris zeicola 26-R-13 GN=COCCADRAFT_40799 PE=4 SV=1 +---RIRDHAENLVPMKRQGRPEEIADGIYYVPQPLVH----KCLLCAISFP----------------------------- +>tr|F8QBH5|F8QBH5_SERL3 Putative uncharacterized protein OS=Serpula lacrymans var. lacrymans (strain S7.3) GN=SERLA73DRAFT_77930 PE=3 SV=1 +--LRQQVLYLTSRPRRRISLLDKVFPLMgVFILTKDSPWcFNGDPGTASV-------------------------------- +>tr|A0A1Q2HR31|A0A1Q2HR31_9BACT Putative oxidoreductase OS=Phycisphaerae bacterium L21-RPul-D3 GN=L21SP3_01605 PE=3 SV=1 +-----------RPSKGQMLSARDIAEHVAAAASGSFLRTAGVVLRNCIKRIK---------------------------- +>tr|A0A0E0RBK8|A0A0E0RBK8_ORYRU Uncharacterized protein OS=Oryza rufipogon PE=3 SV=1 +---------MDRLPMRRGGGGGGXRRWRSSACRRPPTSPaRSSASTADAPL------------------------------ +>tr|A0A1V5I6S8|A0A1V5I6S8_9BACT Putative oxidoreductase OS=Synergistetes bacterium ADurb.BinA166 GN=BWY99_01242 PE=3 SV=1 +---------LAQASRnRRvifGDDPDEAGAKNCFHPDYEEipdtyllevarARRGGEIRV----------------------------------- +>tr|A0A1V5ZXX6|A0A1V5ZXX6_9BACT D-beta-hydroxybutyrate dehydrogenase OS=Synergistetes bacterium ADurb.Bin155 GN=bdhA PE=3 SV=1 +---------LAQAAKnRRiifGDDPDEAGAKNCFHPDHEDipdtyllevarARRSGESTRV---------------------------------- +>tr|A0A0R2PQ56|A0A0R2PQ56_9ACTN Uncharacterized protein OS=Acidimicrobium sp. BACL19 MAG-120924-bin39 GN=ABR58_07525 PE=3 SV=1 +-------VD----GLSSTLLPNEVADVVVAIAQGQHDaragrvlampapaavtALRRWIIEHPGGGVEL--------------------------- +>tr|A0A243RE22|A0A243RE22_9ACTN Short-chain dehydrogenase OS=Streptosporangium sp. M26 GN=CA984_30745 PE=4 SV=1 +-------AA---RFIADVATLPDGGPTGQFLTEKRGQG------------------------------------------ +>tr|A0A1Q6YB70|A0A1Q6YB70_9BACT Uncharacterized protein OS=Acidobacteria bacterium 13_2_20CM_56_17 GN=AUH01_00905 PE=4 SV=1 +-GEELLRKEGEKLRFGRQQKPLDAAYAVVYLLSDESSQVTGTIFHIDAGESTL--------------------------- +>tr|A0A1B1WJL8|A0A1B1WJL8_9MYCO Uncharacterized protein OS=Mycobacterium sp. djl-10 GN=BCA37_18215 PE=4 SV=1 +--DDIRPRLAERSIARRHAQPDEIAGICVYLASSASDFHTADAIRVDGGYLMA--------------------------- +>tr|A0A1Y5SDB2|A0A1Y5SDB2_9RHOB Cyclic-di-GMP-binding biofilm dispersal mediator protein OS=Pseudoruegeria aquimaris GN=bdcA PE=3 SV=1 +------K----TAPAAprsalRSGRCDLlplLAAKLLHLRRGnRGERRPARLIAVmrrSAGPTLF--------------------------- +>tr|A0A061LZK7|A0A061LZK7_9MICO 3-hydroxyacyl-CoA dehydrogenase OS=Leucobacter sp. UCD-THU GN=H490_0106880 PE=4 SV=1 +-EDEIFAEHVKPIPMGRPQTVEEVGELCRFLLSDGARSISGEEIGATGGMAF---------------------------- +>tr|A0A0R2Q082|A0A0R2Q082_9ACTN Uncharacterized protein OS=Acidimicrobium sp. BACL17 MAG-120823-bin42 GN=ABR67_07290 PE=4 SV=1 +-----------DSFSLGVMPVEVAGDLAMRAlteRINGSQWVVSAGFpiaqyehkdpfag------------------------------------ +>tr|A0A0G1JI81|A0A0G1JI81_9BACT Short-chain dehydrogenase/reductase SDR OS=Candidatus Wolfebacteria bacterium GW2011_GWE2_44_13 GN=UW32_C0001G0269 PE=3 SV=1 +-PADVAEVLY-KTAIGEM-KPDSRLIVDTFYHERV--------------------------------------------- +>tr|A0A1B6YTG7|A0A1B6YTG7_9RHOB 3-hydroxyacyl-CoA dehydrogenase OS=Rhodobacteraceae bacterium EhC02 GN=A8B83_07015 PE=3 SV=1 +-AEQARQAMADSNRHKRLISVEEVATAALWLCHPLSGSINAQCIEMAGGQVR---------------------------- +>tr|A0A1B1KF40|A0A1B1KF40_RHOOP Short-chain dehydrogenase/reductase SDR OS=Rhodococcus opacus GN=R1CP_32730 PE=3 SV=1 +-YEQAEQAFVSRAALGRMVTEHEVASSV--LAMLAMPGLCAADIDLSAGMVA---------------------------- +>tr|A0A1Q7R8W2|A0A1Q7R8W2_9BACT Uncharacterized protein OS=Gemmatimonadetes bacterium 13_1_20CM_69_28 GN=AUF60_01125 PE=3 SV=1 +-PPDALRAALETTGQRGLISPEEVARAVLALCEDAQRDTNGEAMVIAEGEGD---------------------------- +>tr|A0A1Q4DE10|A0A1Q4DE10_9PSEU Dehydrogenase OS=Pseudonocardia sp. 73-21 GN=BGP03_23830 PE=3 SV=1 +-----------GFPLLT---AEDVADAVEGIldrAEPGECWFVQPGRepapygfrgvpgpkgstpPPSVSWEA---------------------------- +>tr|J9A6Z6|J9A6Z6_9PROT Uncharacterized protein OS=alpha proteobacterium IMCC14465 GN=IMCC14465_05240 PE=3 SV=1 +----------------PEA-vDASIAA---KTIIDGlgkkpvliftPYYAKISYFlnrfipnFMAKGGDD---------------------------- +>tr|A0A0C1WVH4|A0A0C1WVH4_9CHRO Short-chain dehydrogenase (Fragment) OS=Aphanocapsa montana BDHKU210001 GN=QP59_15335 PE=4 SV=1 +--------------GAGSGIGEAIakvfaeAGAHVFILERDAPKgeAVAQTIRETGG------------------------------- +>tr|A0A0S8BPT1|A0A0S8BPT1_9CHLR Uncharacterized protein OS=Anaerolineae bacterium SG8_19 GN=AMJ56_01715 PE=3 SV=1 +----------------RMI-pPETVADAVCWVLQtPDSVLIRDVPIHNYRNPFE---------------------------- +>tr|D5V2S4|D5V2S4_ARCNC Short-chain dehydrogenase/reductase SDR OS=Arcobacter nitrofigilis (strain ATCC 33309 / DSM 7299 / LMG 7604 / NCTC 12251 / CI) +---------------EYEIYPDSFAKVIKQRLEED-KTNLENEFAQSINY------------------------------ +>tr|A0A136K9F9|A0A136K9F9_9BACT Dehydrogenase OS=Chlorobi bacterium OLB4 GN=UZ04_CHB001000040 PE=3 SV=1 +----------------NSE-sISDVVN---Y-VLD-aPDDIAIEEIivKPVEGNI----------------------------- +>tr|A0A1G3JWB7|A0A1G3JWB7_9SPHN 3-hydroxyacyl-CoA dehydrogenase OS=Sphingomonadales bacterium RIFCSPHIGHO2_01_FULL_65_20 GN=A2792_04560 PE=4 SV=1 +--------------PGVVA-lASENAPTRAILLAGAGTFEQAHI-TMTQGVWV---------------------------- +>tr|A0A1C5V0X4|A0A1C5V0X4_9CLOT Diacetyl reductase [(S)-acetoin forming] OS=uncultured Clostridium sp. GN=budC PE=3 SV=1 +----------------ESE-eVAEACCAI-M-NWD-dSQPVGQAYLlmysedceELKKGHVA---------------------------- +>tr|A0A1Y1VXP9|A0A1Y1VXP9_9FUNG NAD(P)-binding protein OS=Linderina pennispora GN=DL89DRAFT_260663 PE=3 SV=1 +----------------LVVSTEQVAEATVRTI-QD-KKSAGKAYVLIGNWAV---------------------------- +>tr|A0A0F2J5P2|A0A0F2J5P2_9BACT Short-chain dehydrogenase/reductase SDR OS=Candidatus Magnetoovum chiemensis GN=MCHI_000440 PE=3 SV=1 +--------LSALKKKHLLRSPQEPARLAVFLASAQSDNLTGNNGTIDYYSSF---------------------------- +>tr|A0A1G0SLW4|A0A1G0SLW4_9BACT Uncharacterized protein OS=Ignavibacteria bacterium RIFCSPLOWO2_12_FULL_56_21 GN=A3G43_04945 PE=4 SV=1 +----------PNEDPASLRTPDQVTDVFVYLASDDGIGISGQSldatsFVANPGLLS---------------------------- +>tr|A0A1C2DWD7|A0A1C2DWD7_9RHIZ Short-chain dehydrogenase OS=Mesorhizobium sp. UASWS1009 GN=QV13_11600 PE=4 SV=1 +-PEAAQAKTLALHPGNRIATPSEIAKAAVFMISDECPFMNAACLVIDGGLSMLQ-------------------------- +>tr|W4XUG5|W4XUG5_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus GN=Sp-Dhyg_1 PE=4 SV=1 +--DEETAQFfekmKRNHAMRRTGTVDEVSRTIAFMASNDSSFTTGETVGIDGGCHLLVT------------------------- +>tr|R6J7Z7|R6J7Z7_9FIRM Short-chain dehydrogenase/reductase SDR OS=Phascolarctobacterium sp. CAG:207 GN=BN533_01468 PE=4 SV=1 +--DAINE-----LPDY-LMLPDKIASIVVALLSDSMQYISGVAIDVDEAKTW---------------------------- +>tr|K7L1I3|K7L1I3_SOYBN Uncharacterized protein OS=Glycine max GN=GLYMA_07G136100 PE=3 SV=1 +----SVDGIVSQTLVGRMGEAKEISALVAFLCLPAVGVSQLSLLLFIWLLNKI--------------------------- +>tr|A9PI58|A9PI58_POPTR Putative uncharacterized protein OS=Populus trichocarpa PE=2 SV=1 +----V-KELAYRTPH-gTCWRTR-RSLFCCRISLPAWAIVYN--------WTGH--------------------------- +>tr|A0A1U8E0W9|A0A1U8E0W9_CAPAN tropinone reductase homolog OS=Capsicum annuum GN=LOC107841555 PE=3 SV=1 +----INK-LVSRDSCWwSSWRAKRSSAMVSFLCFPCASSITGQVMCVDGGITIN--------------------------- +>tr|G6YF96|G6YF96_9RHIZ Uncharacterized protein OS=Mesorhizobium amorphae CCNWGS0123 GN=MEA186_23216 PE=3 SV=1 +-----QMTMADTNMMKAFLKPADISQAALFLVGPGARHITAQSLNVCAGLAY---------------------------- +>tr|C6VW32|C6VW32_DYAFD Short-chain dehydrogenase/reductase SDR OS=Dyadobacter fermentans (strain ATCC 700827 / DSM 18053 / NS114) GN=Dfer_1939 PE=4 SV +-----TNNPIRHFGAGKSGEAELIAANAMYLALPE-CRLNGLQVYMDGHCQT---------------------------- +>tr|X8JN06|X8JN06_9HOMO 3-ketoacyl-(Acyl-carrier) reductase OS=Rhizoctonia solani AG-3 Rhs1AP GN=RSOL_439980 PE=3 SV=1 +------SIKLPIDLTSKITSPEDIAGLVAFLVSPAAKNITGTIDHYSTPHPM---------------------------- +>tr|M2R7P8|M2R7P8_CERS8 Uncharacterized protein OS=Ceriporiopsis subvermispora (strain B) GN=CERSUDRAFT_116913 PE=3 SV=1 +----TATKTFGLPEGTKVMDPGVIANLVSYLVHPKTDFMTGQTIAVDSGRTM---------------------------- +>tr|A0A1J8R0I6|A0A1J8R0I6_9HOMO Uncharacterized protein OS=Rhizopogon vesiculosus GN=AZE42_12304 PE=4 SV=1 +----YFQERIDASAVGYIGQPEDVASIVSYLASKEAHFVTGKPPIQHVPNAN---------------------------- +>tr|A0A1D7QMC4|A0A1D7QMC4_9SPHI Oxidoreductase OS=Pedobacter steynii GN=BFS30_23245 PE=4 SV=1 +----SADAARERMAIKEYGTAEGIASLVAWVAGEESKYMTGTSLTMDSGTNT---------------------------- +>tr|A0A1Q7XMJ7|A0A1Q7XMJ7_9BACT Uncharacterized protein OS=Candidatus Rokubacteria bacterium 13_1_20CM_2_68_19 GN=AUG14_05450 PE=4 SV=1 +----RWAAV----TRGRPVRLEDVVAAVVYYATCP-LSVTGRIRQVRGTTRS---------------------------- +>tr|A0A1W1GYA4|A0A1W1GYA4_9GAMM 3-oxoacyl-[acyl-carrier protein] reductase OS=Stenotrophomonas sp. 92mfcol6.1 GN=SAMN04488690_2047 PE=3 SV=1 +----PPGWMKSLLRGYPWAALPSLPRSRHWPVG----------------------------------------------- +>tr|A0A1T5K010|A0A1T5K010_9MICO NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Plantibacter cousiniae GN=SAMN06295973_2085 PE=3 SV +-------------MMGRIGGPASQGAELVLAASAA-AVPSGSYLENGSVVSA---------------------------- +>tr|A0A1Y5TTA9|A0A1Y5TTA9_9PROT Enoyl-[acyl-carrier-protein] reductase [NADPH] FabL OS=Oceanibacterium hippocampi GN=fabL PE=3 SV=1 +---------DSLPPLDR-ATCEAIAEAIMRLIEDEGGADSGQIVDVERPGRT---------------------------- +>tr|A0A0T5ZDZ3|A0A0T5ZDZ3_9ARCH Short-chain dehydrogenase/reductase SDR OS=Thaumarchaeota archaeon CSP1-1 GN=XU09_C0007G0151 PE=3 SV=1 +-----PTSLSAetvAKAILRAANSSrleiivpAVVRGAVWTKQTFPYLINP----IIGSTFRK--------------------------- +>tr|X1A5C1|X1A5C1_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=S01H4_00846 PE=4 SV=1 +------DFQNLPYALEaf-SVSSEEVGKLCV---------------EIcCSGTRKS--------------------------- +>tr|A0A0J5QZL0|A0A0J5QZL0_9BACI Uncharacterized protein OS=Bacillus pseudalcaliphilus GN=AB990_11695 PE=3 SV=1 +-----GAKIGATTGPNIAATAEEIADAVIFAM-NNGKVLTGSIINCAGGQIYN--------------------------- +>tr|A0A094XJ83|A0A094XJ83_BACAO 3-oxoacyl-ACP reductase OS=Bacillus alcalophilus ATCC 27647 = CGMCC 1.3604 GN=BALCAV_0202540 PE=3 SV=1 +--------PNCD----yPLLKPSQLLPLFDQIIHNQ-GSVNGKRFEIV--------------------------------- +>tr|A0A1Q9PLX5|A0A1Q9PLX5_BACPF 3-oxoacyl-ACP reductase OS=Bacillus pseudofirmus GN=BTR22_15925 PE=4 SV=1 +--------PDCN----ySLSSPEEIARALESVVLDETMSLNGKRFEAQ--------------------------------- +>tr|A0A1W0WNN4|A0A1W0WNN4_HYPDU Dehydrogenase/reductase SDR family member 11 OS=Hypsibius dujardini GN=BV898_09162 PE=3 SV=1 +-----AEAFASTATPYKVLDSEDVAEAIVYILSVPAHVNIDELTLTPQGQHAL--------------------------- +>tr|A0A0L0MBH4|A0A0L0MBH4_9BURK 3-oxoacyl-[acyl-carrier protein] reductase OS=Candidatus Burkholderia verschuerenii GN=BVER_01225c PE=3 SV=1 +-----LKATVPVYRTTRrr---------CACSRNVHQSGCVVHHrTDLVCVRRPF---------------------------- +>tr|A0A087LRQ5|A0A087LRQ5_9RHIZ Short-chain dehydrogenase OS=Devosia sp. 17-2-E-8 GN=JP74_08395 PE=3 SV=1 +----EGDSW--KNTLG-VGSPEDVVGPLMFLL-SDAATMSASVLSRDMAYTK---------------------------- +>tr|A0A0D0KEZ4|A0A0D0KEZ4_9PSED Oxidoreductase OS=Pseudomonas fulva GN=RU08_20330 PE=3 SV=1 +----GAREAMREFRKIAIRPDAIARAVA--YAIEQPADVDVSELVVRPTASI---------------------------- +>tr|D2RVS6|D2RVS6_HALTV Short-chain dehydrogenase/reductase SDR OS=Haloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / NCIMB 13204 / VKM B-1734) G +----EREEI--LDPDV-MNDAA-----VLLAA-QGPDGVSGEsMPAEEWEQRL---------------------------- +>tr|A0A1N6SYI0|A0A1N6SYI0_9RHIZ 3alpha(Or 20beta)-hydroxysteroid dehydrogenase/3-oxoacyl-[acyl-carrier protein] reductase OS=Rhizobium sp. RU35A GN=SAMN0588059 +----LRKIW--KDPIE-LTPAF-----VHLAL-QDASGITDQrIRAWDMVVEL---------------------------- +>tr|A0A139AGR8|A0A139AGR8_GONPR Uncharacterized protein OS=Gonapodya prolifera JEL478 GN=M427DRAFT_44163 PE=4 SV=1 +-----FKTVLAHNHRGGRGCVG------IFFPKASQ----HNQLPYQGACQR---------------------------- +>tr|A0A158GDX7|A0A158GDX7_9BURK Short-chain dehydrogenase OS=Caballeronia sordidicola GN=AWB64_02577 PE=4 SV=1 +-----YAEALALNPTKRMATPQDRKCGCVHCEP-HCEFCQRHESrgrrRADsrrTAMSR---------------------------- +>tr|A0A1L9TAJ2|A0A1L9TAJ2_9EURO Uncharacterized protein OS=Aspergillus sydowii CBS 593.65 GN=ASPSYDRAFT_80307 PE=4 SV=1 +-----VGERLSDSPLKSLGNVNELVkSVALLLPGRVPSVVAGSHCLVDGDIRI---------------------------- +>tr|A0A0Q5UJW1|A0A0Q5UJW1_9FLAO Uncharacterized protein OS=Flavobacterium sp. Leaf359 GN=ASG38_10845 PE=4 SV=1 +---AKIQAAKARHPMNTFGTSAEIAKV-AFHMLTEYRWVTGQVYNINGGLGTIIK------------------------- +>tr|A0A0Q8ZQW9|A0A0Q8ZQW9_9FLAO Oxidoreductase OS=Flavobacterium sp. Root901 GN=ASE21_20995 PE=4 SV=1 +---KMRETIKERHPMKNYLQSQEVAQMADYLISDSASSISGQVFVMDYGLVSFKI------------------------- +>tr|U9VZ63|U9VZ63_9CYAN Short-chain dehydrogenase OS=Leptolyngbya sp. Heron Island J GN=N836_34470 PE=4 SV=1 +--PESVAFISQLAPMNRLGTVAEMMPAVRMLLSPEGMWMNGETLYINNGYL----------------------------- +>tr|A0A1H1KUY2|A0A1H1KUY2_9MICO NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Agrococcus carbonis GN=SAMN04489719_0121 PE=4 SV=1 +--PGA--IAGRREDAGRLYNVEEFAHEVALAAVEPVPADNTRLV---GDVS----------------------------- +>tr|A0A1N5YQP9|A0A1N5YQP9_9MYCO Putative short chain dehydrogenase/reductase OS=Mycobacterium abscessus subsp. bolletii GN=SAMEA2068811_00565 PE=4 SV=1 +--DENIAWLESMSINGQIGRGDDILPVARLLVLPESGWTTAQTIFVNGGII----------------------------- +>tr|A0A1Q4UVU1|A0A1Q4UVU1_9PROT Uncharacterized protein OS=Thalassospira sp. TSL5-1 GN=LF95_07195 PE=4 SV=1 +----------LTASFGNASLVGDITSGLSFLAGPDADFITGTTFNFDHHVA----------------------------- +>tr|A0A0T5VLN2|A0A0T5VLN2_9SPHI Oxidoreductase OS=Pedobacter ginsenosidimutans GN=ASU31_18275 PE=4 SV=1 +-TEEERQRTIDLHPVKKLGTVEEIGGWCVFLSSKYAGFASGTTYLIDGGRNAVL-------------------------- +>tr|A0A136M5Z1|A0A136M5Z1_9BACT 3-oxoacyl-(Acyl-carrier-protein) reductase OS=Bacteroidetes bacterium OLB12 GN=UZ12_BCD005000693 PE=3 SV=1 +-PEEVFHECEEMHLLKKSGRPDRSRRVYCLSR-IGQSFIHNGASISD--------------------------------- +>tr|A0A1V0HU61|A0A1V0HU61_9RHOB Oxidoreductase OS=Rhodovulum sp. MB263 GN=B5V46_02015 PE=3 SV=1 +------------ARAAEMIQPEDMAALALHVAGMNPNVA--------IHEI----------------------------- +>tr|A0A1V4WBH0|A0A1V4WBH0_9FIRM Cyclopentanol dehydrogenase OS=Pelotomaculum sp. PtaB.Bin104 GN=cpnA PE=3 SV=1 +--VRD--LFVSRQTFpKKEGDPQLIGEFCLHIINNW--FFNRTGLVCDAGYI----------------------------- +>tr|A0A099CRC6|A0A099CRC6_9MYCO Oxidoreductase OS=Mycobacterium rufum GN=EU78_14260 PE=4 SV=1 +-----DEAHREtVRLKMGRATAWETGYAVLYLLADESRFMTGQQIRLDGGATAVR-------------------------- +>tr|A0A149QGT3|A0A149QGT3_9BURK Uncharacterized protein OS=Caballeronia megalochromosomata GN=CR51_22955 PE=3 SV=1 +---DMMRSRADSVPMRWQGEGGTLVRTQHSLhrMTHDSSL---------GRYSPW--------------------------- +>tr|A0A151E3B8|A0A151E3B8_9EURY Uncharacterized protein OS=Thermoplasmatales archaeon SG8-52-4 GN=AYK24_01405 PE=4 SV=1 +-----IQFPFSQVLLTRIGDL---------FPTSAYDAVPVH-MQKGDGYPV---------------------------- +>tr|A0A165U602|A0A165U602_9GAMM Uncharacterized protein OS=Halioglobus sp. HI00S01 GN=A3709_15835 PE=3 SV=1 +-----H--VGTYMDvGMEAGQ---VGDAVAYalalpggvavdlleIRPNIPTPKNSQT------------------------------------- +>tr|A0A0D0SJW5|A0A0D0SJW5_9FIRM TWA4_scaffold00001, whole genome shotgun sequence OS=Lachnospiraceae bacterium TWA4 GN=P261_02286 PE=3 SV=1 +-----KEFANHSVPMKRYGKEGELNSTAIFLERRNLVM------------------------------------------ +>tr|A0A1Q4BKG8|A0A1Q4BKG8_9RHIZ Short-chain dehydrogenase OS=Rhizobiales bacterium 62-17 GN=BGP04_07055 PE=3 SV=1 +------EVAAVIVlMaSMPDTTNMLD-TTILP----------------IAQPFL---------------------------- +>tr|A0A194VXL6|A0A194VXL6_9PEZI 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase OS=Valsa mali GN=VM1G_03746 PE=4 SV=1 +-----EEFASKFSYLGRFGMPHEVAQSSLWLSSPGSSYITARRWRYPGDVR----------------------------- +>tr|A0A0F4YN11|A0A0F4YN11_TALEM Glucose 1-dehydrogenase OS=Rasamsonia emersonii CBS 393.64 GN=T310_7004 PE=4 SV=1 +-----DEFAPNVSYLRRFGQGHEVAQGSLWLSSNAASIYKFL-------------------------------------- +>tr|A0A1Q4FDW4|A0A1Q4FDW4_9GAMM Uncharacterized protein OS=Xanthomonadales bacterium 63-13 GN=BGP25_00150 PE=4 SV=1 +--------QKNQALTGPYGAPADIVRAIEFART--AHFLNATIISVDGGRSRW--------------------------- +>tr|A0A177EUU0|A0A177EUU0_9EURO Uncharacterized protein OS=Fonsecaea monophora GN=AYO21_10028 PE=3 SV=1 +----------------STGQVEEVQQQLLRLQKDNEMeDKLPKHDTVHSVFNDYTQ------------------------- +>tr|I7CQ76|I7CQ76_NATSJ Short-chain dehydrogenase/reductase SDR OS=Natrinema sp. (strain J7-2) GN=NJ7G_0905 PE=3 SV=1 +---------DDAAALLAAQGPDGVTG-------E--SMTTDEWEDRLTES------------------------------ +>tr|E6SD15|E6SD15_INTC7 Short-chain dehydrogenase/reductase SDR OS=Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KI +---------GQDPSQGSFMEPQDIAAAVAYTLRQ-pRRMRTE-------LWTM---------------------------- +>tr|A3X0Y2|A3X0Y2_9BRAD Glucose 1-dehydrogenase OS=Nitrobacter sp. Nb-311A GN=NB311A_09306 PE=3 SV=1 +---EKMAQLPKLIPYGRIGEPETSAGPSSGLRPTRPtTSRVGHSLLMVA-------------------------------- +>tr|A0A1F7PCX4|A0A1F7PCX4_9BACT Uncharacterized protein OS=Candidatus Rokubacteria bacterium RIFCSPLOWO2_12_FULL_71_22 GN=A3F92_14835 PE=4 SV=1 +---AYKAAAIAGTPLGRLVTEGEIARMVVLLCSAAFDFVTGRAIILDGGRTLPVF------------------------- +>tr|A0A1Z9A5B0|A0A1Z9A5B0_9EURY Oxidoreductase OS=Euryarchaeota archaeon TMED99 GN=CBC59_07040 PE=4 SV=1 +----ALNNLTQNTPLNLTVTPDQVAQGIYSFIGI-NKVVTGETMLMDGGHHL---------------------------- +>tr|A0A1Z9B6L3|A0A1Z9B6L3_9BACT Uncharacterized protein OS=bacterium TMED88 GN=CBC48_13290 PE=4 SV=1 +----VYERVMNAlawfHPRRVIDQPGPVAEAIALCCTDAAEMFAGQTVDLDGGSIF---------------------------- +>tr|A0A1F8LR51|A0A1F8LR51_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_13_48_10 GN=A2Y88_13195 PE=4 SV=1 +-EWNinTLHQWLGSFPSVGLGHHSDLVSLVLFLCSDAASSLTGQVISLNLGNK----------------------------- +>tr|A0A1M4Y7G1|A0A1M4Y7G1_9BACL 3-oxoacyl-[acyl-carrier protein] reductase OS=Seinonella peptonophila GN=SAMN05444392_10682 PE=4 SV=1 +-----------------FAEIEQTASSVVFLTERGAK---PTIFAATGGEVL---------------------------- +>tr|G4HDE1|G4HDE1_9BACL Short-chain dehydrogenase/reductase SDR OS=Paenibacillus lactis 154 GN=PaelaDRAFT_1994 PE=3 SV=1 +-------------PLGRPNPR-RLPSLPSVLEtqaSVCCSIC----------------------------------------- +>tr|A0A0C7KVP6|A0A0C7KVP6_KLEVA HbdH protein OS=Klebsiella variicola GN=hbdH PE=3 SV=1 +---PAPSCWRKNSPPGSLSPRSN---WAKWRCFCAAMPLsrcaAPRGIWMAAGWRS---------------------------- +>tr|A0A1F8I478|A0A1F8I478_9PROT 3-hydroxybutyrate dehydrogenase OS=Caulobacterales bacterium RIFCSPHIGHO2_01_FULL_70_19 GN=A2623_03965 PE=3 SV=1 +---VLKDVILGSQPTKRFVTTDELVGMMLYLVSDLGASANGASFSIDGGWTA---------------------------- +>tr|A0A1D2MAV5|A0A1D2MAV5_ORCCI D-beta-hydroxybutyrate dehydrogenase (Fragment) OS=Orchesella cincta GN=Ocin01_16553 PE=3 SV=1 +---AKMELLLEKQPSGEFCFSAQLLRIK---------------------------------------------------- +>tr|A0A1A7R4S6|A0A1A7R4S6_9FLAO D-beta-hydroxybutyrate dehydrogenase OS=Gelidibacter algens GN=A9996_04020 PE=3 SV=1 +---VVQKVMLKKQAVKQFIPVEAIADMALLLAKESSTTITGTSFALDGGWSA---------------------------- +>tr|W4M5R9|W4M5R9_9BACT Uncharacterized protein (Fragment) OS=Candidatus Entotheonella sp. TSY2 GN=ETSY2_22310 PE=4 SV=1 +---QELEERRLRIPLERVGISVPTPWPQNDLAKrypksTPSSSRSNPhqpiRVPVAFSSTAQRI------------------------- +>tr|A0A1E5G8I7|A0A1E5G8I7_9ENTE Uncharacterized protein OS=Enterococcus ureasiticus GN=BCR21_15645 PE=4 SV=1 +------HCLRAKIPNQTFITNESVTASILFLHQENASGIRGQNLVIDNGMTIV--------------------------- +>tr|A0A1X2FFV2|A0A1X2FFV2_9MYCO Uncharacterized protein OS=Mycobacterium wolinskyi GN=AWC31_17770 PE=4 SV=1 +----------RKLPPCPTRHGSGSGRGQRLPREPARIIRHGC--RIHGERW----------------------------- +>tr|A0A1T5E6T7|A0A1T5E6T7_9SPHN NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Sphingopyxis flava GN=SAMN06295937_101934 PE=3 SV=1 +----------LHLTDGATNSARQISAAVALLASELSDMTNGASLDVGGANA----------------------------- +>tr|Q0CV36|Q0CV36_ASPTN Uncharacterized protein OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=ATEG_02448 PE=3 SV=1 +---AARAVWEAENMLGPPRVPGGVPRCGPLRPERRQQ-LHDRQLAAD--------------------------------- +>tr|A0A1V4E8C9|A0A1V4E8C9_9ACTN Uncharacterized protein OS=Microbispora sp. GKU 823 GN=B1L11_27330 PE=3 SV=1 +PTDEERAEHLRRFPLGY-GGSGPIAAAVRYLVHPSGDWVSGTVMNVSGGEH----------------------------- +>tr|A0A1P8K0U8|A0A1P8K0U8_9BURK Oxidoreductase OS=Rhodoferax sp. DCY110 GN=RD110_22450 PE=3 SV=1 +PSEEDKARMLQEADLGRTIR--FIAEMPPHVCINEMVISPVWNRTYIGDRK----------------------------- +>tr|B9L366|B9L366_THERP 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier protein reductase) OS=Thermomicrobium roseum (strain ATCC 2 +------DWVQGEGPHRAIHPEEELGWIVAYLCH---PNMtaisgaaipvdRGvsngigdfAELKRRSG------------------------------- +>tr|S4MI57|S4MI57_9ACTN Putative D-beta-hydroxybutyrate dehydrogenase OS=Streptomyces afghaniensis 772 GN=STAFG_6694 PE=3 SV=1 +------DWLGRFAEHAATKKITTVEQIAAVASLLASE-AgavspaR---------------------------------------- +>tr|D6TT74|D6TT74_9CHLR Short-chain dehydrogenase/reductase SDR OS=Ktedonobacter racemifer DSM 44963 GN=Krac_4617 PE=3 SV=1 +------DRFKGFYEQGTLLEPSR--PARLVVNLLRGESTgeivsiydqRGqELLKQ---------------------------------- +>tr|A0A0Q8H281|A0A0Q8H281_9BURK Short-chain dehydrogenase OS=Pelomonas sp. Root662 GN=ASD88_05415 PE=3 SV=1 +-------KLQ---------DPLNVACAVRYvLQQPQGTVIPELTVLpTRES------------------------------- +>tr|D8F6Z5|D8F6Z5_9DELT Oxidoreductase, short chain dehydrogenase/reductase family protein OS=delta proteobacterium NaphS2 GN=NPH_4234 PE=3 SV=1 +------EKYKSFMD-----SPEAVARGVINqLDSER------LVVFpTEKP------------------------------- +>tr|J2S5L3|J2S5L3_9PSED Short-chain alcohol dehydrogenase OS=Pseudomonas sp. GM48 GN=PMI28_00564 PE=3 SV=1 +--------KAAQELNKIAIAPEDIGRAVAYALNQPANVTVNDLIISPTR------------------------------- +>tr|A0A0F9MZ44|A0A0F9MZ44_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_1015010 PE=4 SV=1 +------------ASDEWKIQPEDIGEIVVDLLKLNSRTLPSKIEVRPSR------------------------------- +>tr|A0A1N7STA8|A0A1N7STA8_9BURK Short-chain dehydrogenase/reductase SDR OS=Paraburkholderia piptadeniae GN=BN2476_930004 PE=3 SV=1 +-------NDDEAGKRGPLRQAGRNRCGRGLSREPRSRYTTGESLTVDGG------------------------------- +>tr|A0A1J1HQX4|A0A1J1HQX4_9DIPT CLUMA_CG002381, isoform A OS=Clunio marinus GN=CLUMA_CG002381 PE=3 SV=1 +------EYVAEKSVEGI-----LINKRNIFITPDYAHFIVNNLPDRVRRHLK---------------------------- +>tr|A0A1V5DY02|A0A1V5DY02_9DELT Putative oxidoreductase OS=Smithella sp. PtaU1.Bin162 GN=A4E71_00996 PE=3 SV=1 +--------VE--KTKKYMESPDKVARGIIDQLDSE------RL---VVF------------------------------- +>tr|A0A017HQV7|A0A017HQV7_9RHOB 3-oxoacyl-[acyl-carrier protein] reductase OS=Rubellimicrobium mesophilum DSM 19309 GN=Rumeso_01663 PE=3 SV=1 +-----------HAPTSARHGGGTA-D-FMVSSARRARPMpsAGPTSTTAGC------------------------------- +>tr|A0A1I5CPB4|A0A1I5CPB4_9ACTN NADP-dependent 3-hydroxy acid dehydrogenase YdfG OS=Geodermatophilus obscurus GN=SAMN05660359_00442 PE=3 SV=1 +---SVEDAAREVVRVARLGQDGPTGTFTSW-------------------NGMT--------------------------- +>tr|A0A1E5GWB0|A0A1E5GWB0_9ENTE Uncharacterized protein OS=Enterococcus termitis GN=BCR25_03845 PE=3 SV=1 +----KERATSES-LLDIKNNLDSLSCMLAFLSSNLSNGVTGQVFNVDSRLI----------------------------- +>tr|A0A1V5SI02|A0A1V5SI02_9BACT 3-oxoacyl-(Acyl-carrier-protein) reductase FabG OS=Candidatus Omnitrophica bacterium ADurb.Bin277 GN=fabG_2 PE=4 SV=1 +----AMQNALERSPLRTYSDPEEVAAFLVYLSSNLVRQVTGQVFHFESRPL----------------------------- +>tr|A0A0Q7P2B3|A0A0Q7P2B3_9RHIZ Uncharacterized protein OS=Rhizobium sp. Root483D2 GN=ASD32_15600 PE=4 SV=1 +------LRRARLPGAGTSGATDDIAFIRNDLVA-SAGWR-GW-------------------------------------- +>tr|A0A1Q7DGM3|A0A1Q7DGM3_9ACTN Uncharacterized protein OS=Actinobacteria bacterium 13_2_20CM_2_66_6 GN=AUI15_07975 PE=3 SV=1 +-----AIEVAPGSAKPRLRSPRTRARPAAAVI------------------------------------------------ +>tr|A0A202E020|A0A202E020_9BACT Uncharacterized protein OS=bacterium K02(2017) GN=BVY03_02940 PE=4 SV=1 +----IFESSQKCAPHGGFVEPSQLAKIILLLLKPEANWLATKTIHMDGGLG----------------------------- +>tr|F3C570|F3C570_PSESG 3-oxoacyl-(Acyl-carrier-protein) reductase OS=Pseudomonas savastanoi pv. glycinea str. race 4 GN=Pgy4_14111 PE=3 SV=1 +--SAWKNRQ--RLPSCRWGVSVWPRKLRRWrCSWPaSRVATCSSARR----------------------------------- +>tr|A0A0N0D8H7|A0A0N0D8H7_9RHOB Gluconate 5-dehydrogenase OS=Shimia sp. SK013 GN=gno_2 PE=3 SV=1 +---AVTAKLKSASALGRWGEPAELPPPSFFSPHSLQAMSLATSLPSMAGTPATIRRQ-KKTPRRS--------------- +>tr|A0A1X1EY89|A0A1X1EY89_PANCY Oxidoreductase OS=Pantoea cypripedii GN=HA50_17005 PE=4 SV=1 +-YEEQVSVDLNSVPMTSVVDPADVASAMSWLISHESKHTTGSVMTIDAGFTAR--------------------------- +>tr|A0A1Q6YY77|A0A1Q6YY77_9BACT Uncharacterized protein OS=Candidatus Rokubacteria bacterium 13_2_20CM_2_64_8 GN=AUI04_03935 PE=4 SV=1 +MTKETVDLLILSSRPGCAhvGPRPHAAARRN-------SM------------------------------------------ +>tr|A0A1Q2Z8B8|A0A1Q2Z8B8_9ACTN Putative oxidoreductase OS=Streptomyces acidiscabies GN=Saa2_02594 PE=4 SV=1 +PTEETenpwQRRvdswLAAQRRAGRYaALPDALGNLLR--------LIGGEADALTGRYL----------------------------- +>tr|A0A0U1M3J0|A0A0U1M3J0_9EURO Uncharacterized protein OS=Talaromyces islandicus GN=bdhA PE=4 SV=1 +-----QGIINAMVPIKRAAECEEVAETVAFLCSPRELHQRHEHHYRCGCHDD---------------------------- +>tr|G7XDK2|G7XDK2_ASPKW Oxidoreductase, short-chain dehydrogenase/reductase family OS=Aspergillus kawachii (strain NBRC 4308) GN=AKAW_02967 PE=3 SV=1 +-----NQfdlplvgGNSDDRASGGGRSEFGICDESSGADGPRASFVTGAGWMVDGGATL---------------------------- +>tr|A2QNS5|A2QNS5_ASPNC Aspergillus niger contig An07c0190, genomic contig OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) GN=An07g06820 PE=4 SV= +-----RAEIEAVIPIKRAAESDELRREAEGSMNMIV------DLIMGR-------------------------------- +>tr|A0A081BYK1|A0A081BYK1_9BACT Short-chain dehydrogenase/reductase SDR OS=bacterium UASB270 GN=U27_04373 PE=3 SV=1 +-------YSK-QLPm-GKVGTPEEVARIVVlCSSYIm-DPLINQTLNAWWGRG------------------------------ +>tr|A0A0U1AID8|A0A0U1AID8_9MYCO 3-oxoacyl-ACP reductase OS=Mycobacterium abscessus GN=fabG_29 PE=3 SV=1 +--------TS-PYTYxvIAVGwSPPRGRQWCCWRAS-RRHWRAVRTCtarwrDLAARWT----------------------------- +>tr|A0A1S8W3Z0|A0A1S8W3Z0_9FUNG Uncharacterized protein OS=Batrachochytrium salamandrivorans GN=BSLG_01697 PE=3 SV=1 +----------------SMLVPIHLVIEAFFLAI-EDDTLKGAVirVTPKYGID----------------------------- +>tr|A0A1Q9RUW6|A0A1Q9RUW6_9PSEU Uncharacterized protein OS=Pseudonocardia sp. CNS-004 GN=BJF90_37860 PE=3 SV=1 +-------DTAILFSQRSLLTPTAVADAAVALLDGRASCV-GPRPPLRGDAD----------------------------- +>tr|F4P0I8|F4P0I8_BATDJ Uncharacterized protein OS=Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) GN=BATDEDRAFT_24146 PE=3 SV=1 +----------------HMKVPISLVIDAFILGI-EDQSLKGDVirVTPEYGID----------------------------- +>tr|A0A0R2MXQ2|A0A0R2MXQ2_9LACO Acetoin dehydrogenase OS=Lactobacillus saniviri JCM 17471 = DSM 24301 GN=IV56_GL001169 PE=3 SV=1 +------DQLISQTKDRQPSKLDSVVDGVSFLAGPRSGYLTGQIMSVGNGMQ----------------------------- +>sp|Q04520|BUDC_RAOTE Diacetyl reductase [(S)-acetoin forming] OS=Raoultella terrigena GN=budC PE=3 SV=1 +------AR----L---NLPNASPLAACRSLKTSPPACRSSPARIPTI--------------------------------- +>tr|G9XEZ0|G9XEZ0_9FIRM Uncharacterized protein OS=Peptoanaerobacter stomatis GN=HMPREF9628_02143 PE=4 SV=1 +--DDDISALKEMSALNKVSYPQEIAKTILFLCSEDTSSYTGQVLSPNCGI------------------------------ +>tr|E3TDS7|E3TDS7_ICTPU Dehydrogenase/reductase sdr family member 4 OS=Ictalurus punctatus GN=DHRS4 PE=2 SV=1 +---------LKMLCIKRLGKPEDIGGVIAFLVFRRGLIHHRRDYYCHrwhqlqtiKGTMC---------------------------- +>tr|Q4S0T0|Q4S0T0_TETNG Chromosome undetermined SCAF14779, whole genome shotgun sequence OS=Tetraodon nigroviridis GN=GSTENG00025883001 PE=3 SV=1 +---------QeaaQHQKDRTSGGNRQRGGFFV---FGGGLLHHGGDHHGQrrdglptlspalasepfsdmeKKNPC---------------------------- +>tr|A0A192WHW0|A0A192WHW0_9RHIZ Short-chain dehydrogenase/reductase SDR family protein OS=Rhizobium sp. N941 GN=AMK07_PB00172 PE=4 SV=1 +----AADFQRSLTSLGRYGEPSESER--RRLSSKLRREITGATLTADGGAIALRTS------------------------ +>tr|A0A0Q6H7I7|A0A0Q6H7I7_9RHIZ Uncharacterized protein OS=Rhizobium sp. Leaf453 GN=ASG68_04120 PE=4 SV=1 +---SGLLHHRARLPGSRAISR-----------SGDVAFIRNELVASTGWR------------------------------ +>tr|A0A165NLU3|A0A165NLU3_9RHOB 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Pseudovibrio sp. W74 GN=fabG_13 PE=3 SV=1 +---DRPALVAAATPLGRIASLQILQRLlSGWDHPGQDS------------------------------------------- +>tr|A0A137QIM6|A0A137QIM6_9AGAR Diacetyl reductase [(S)-acetoin forming] (Fragment) OS=Leucoagaricus sp. SymC.cos GN=AN958_09270 PE=4 SV=1 +---NFVEPSMLDATYGQMGSPDQIAKLVSYLACKEAQFITGKACTSPLFQF----------------------------- +>tr|A0A0F5BZ02|A0A0F5BZ02_PRIPA Dehydrogenase OS=Pristionchus pacificus GN=PRIPAC_14091 PE=4 SV=1 +--EEARERALQSIPLNRLGQADECADVVSFLVSSILFFNDSQSSNEEGRC------------------------------ +>tr|B8XIJ9|B8XIJ9_KARVE Ketoacyl-reductase like protein OS=Karlodinium veneficum PE=2 SV=1 +--------------TGMLIQPEEIIDLMDYQLKlPANRVLKRVVFFPKGEWH----------------------------- +>tr|A0A0S8FCS5|A0A0S8FCS5_9BACT Uncharacterized protein OS=Gemmatimonas sp. SG8_38_2 GN=AMS21_11360 PE=3 SV=1 +--------------LQLLAHDDRALPSRVELRPARPRPSAG--------------------------------------- +>tr|H0E8F1|H0E8F1_9ACTN Short-chain dehydrogenase/reductase SDR OS=Patulibacter medicamentivorans GN=PAI11_31120 PE=4 SV=1 +-------------------APEDLAATILDLCGDPAG-ERRADVHVPGEPG----------------------------- +>tr|A0A1Q4DE10|A0A1Q4DE10_9PSEU Dehydrogenase OS=Pseudonocardia sp. 73-21 GN=BGP03_23830 PE=4 SV=1 +--------------DAVEGILDRAEPGECWFVQPGREPAP-YGFRGVPGpKGS---------------------------- +>tr|A0A1Q1FKG6|A0A1Q1FKG6_9EURY Dehydrogenase OS=Halorientalis sp. IM1011 GN=BV210_11240 PE=3 SV=1 +--------------------VMNDAATGLLA-----QGPDGVTGESMPAE------------------------------ +>tr|W7SSZ9|W7SSZ9_9PSEU 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase OS=Kutzneria sp. 744 GN=KUTG_08234 PE=3 SV=1 +---------------GALVPPDRVAGVGD------GRLRRRPVHHRHRdprrrrRAR----------------------------- +>tr|K2AGM7|K2AGM7_9ZZZZ Uncharacterized protein OS=groundwater metagenome GN=ACD_60C00009G0001 PE=4 SV=1 +-PDYYQQRIS-QMPMGRFAHPSEIATYVTDLACNTSIMCAGSLIELTGGY------------------------------ +>tr|D3RUK7|D3RUK7_ALLVD Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) OS=Allochromatium vinosum (strain ATC +-PDRHDRFLE-KMTYGQFVPSIEVAHYIVSLCLVESNMINGSIITIDGGV------------------------------ +>tr|W0DD59|W0DD59_CAMFE Short-chain dehydrogenase/reductase family protein OS=Campylobacter fetus subsp. venerealis cfvi03/293 GN=CFVI03293_1623 PE=4 S +-PNTFNQKLQ-NSIFKEFATPNHIANFVLSMLNSNNKFINGGEFIINGGE------------------------------ +>tr|A0A099DL15|A0A099DL15_9HELI Uncharacterized protein OS=Helicobacter jaachi GN=LS71_09105 PE=4 SV=1 +-EAHYKQIES-MQPLGRFGKAEEVGAFVGSVLEGHNMLMSGAIFELSGAV------------------------------ +>tr|A0A1Q7B3J7|A0A1Q7B3J7_9PROT Uncharacterized protein OS=Alphaproteobacteria bacterium 13_2_20CM_2_64_7 GN=AUI16_30425 PE=4 SV=1 +--------DTVATAAIRAirknkgiavvGRAARALWLLTRLSPAFVDWLNRRGWRSLSA------------------------------- +>tr|I0IHM6|I0IHM6_PHYMF Putative oxidoreductase OS=Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01) GN=PSMK_26050 PE=3 SV=1 +-S-------ERAIPPEKALDPISVAGVIHDLVTGEREEASGSTIKLPSP------------------------------- +>tr|A0A1F9GJH1|A0A1F9GJH1_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFCSPLOWO2_01_FULL_45_74 GN=A2979_04510 PE=4 SV=1 +--------TLPWIP----MKPSYIAEVIDWILSQPAHVVISSIEiqNFKKG------------------------------- +>tr|A0A1J5TPN5|A0A1J5TPN5_9EURY Uncharacterized protein OS=Marine Group III euryarchaeote CG-Epi2 GN=BET99_01270 PE=4 SV=1 +--ETASQAASQKIPIKRVNEKEEIATVLKWLLTDAPDNFTGQVLHTDGGMSKVLV------------------------- +>tr|M4ZVI3|M4ZVI3_9ACTN Putative oxidoreductase OS=Ilumatobacter coccineus YM16-304 GN=YM304_01880 PE=3 SV=1 +----------DPEYVAKWMTPAQIAQIVSELLAEg-RDGRTANSI----GLYAGY-------------------------- +>tr|A0A0F9SEA3|A0A0F9SEA3_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0529920 PE=4 SV=1 +----------PVPRLLr-PPVPKNIADLALFLGS-sASDHITGELLIIRGHFPWDR-------------------------- +>tr|A0A1Q4RWR4|A0A1Q4RWR4_9CYAN Oxidoreductase OS=Calothrix sp. HK-06 GN=NIES2101_11855 PE=4 SV=1 +-------------RREQLGqitnvpvveKPKDVANAIWDAVSNq-KSEVMVGSANVSQGMYRLL-------------------------- +>tr|A0A1Q6G9U8|A0A1Q6G9U8_9BACE Uncharacterized protein OS=Bacteroides plebeius GN=BHV76_10180 PE=3 SV=1 +----------SFHPLNHIIFFEQIAALAAFMIGNv-SKFQVGEVKKACATENV---------------------------- +>tr|A0A1V2PDJ6|A0A1V2PDJ6_9ACTN Dehydrogenase OS=Kribbella sp. ALI-6-A GN=BWI15_11660 PE=3 SV=1 +----------ASYPGRTVN---RVLTWPARLLPRa-A-LV-----RIAAAFNRRL-------------------------- +>tr|A0A1W2FYE8|A0A1W2FYE8_KIBAR Short chain dehydrogenase OS=Kibdelosporangium aridum GN=SAMN05661093_10566 PE=4 SV=1 +---PAADYLRGFIAVGHYGHAQDVAGMVAYPGRSW--WSPRQRKLCPGGRR----------------------------- +>tr|A0A1F4CSY7|A0A1F4CSY7_9PROT Uncharacterized protein OS=Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_62_13 GN=A3G24_11460 PE=4 SV=1 +--QEAYNSILREQGIRRFGRPEELAIFIGMLASNAVEFLQGSVIDMDGGQT----------------------------- +>tr|A0A1X6ZMJ1|A0A1X6ZMJ1_9RHOB 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Pseudooceanicola marinus GN=fabG_10 PE=4 SV=1 +MPpEEAARQILAGIRS---GEDEIDVGKVRLlrlLLRLSPALAYGIIRRS---------------------------------- +>tr|A6WAZ2|A6WAZ2_KINRD Short-chain dehydrogenase/reductase SDR OS=Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) GN=Krad_2506 +-----GDEfhrvtprsgpwvdA--EAPLRTQPMPRstsRvrwldgSVDSpcssPEGRCSERAGPL----H-VS--------------------------------- +>tr|A0A0Q6ST04|A0A0Q6ST04_9RHIZ Uncharacterized protein OS=Rhizobium sp. Root1204 GN=ASC96_01830 PE=3 SV=1 +-----RTTrrttav----ASLRRGRLP--gAG---TLAASDDIAFIRNDLV-ASTGW------------------------------ +>tr|A0A1M4RXY2|A0A1M4RXY2_9ACTO Short-chain dehydrogenase/reductase sdr OS=Actinomyces glycerinitolerans GN=ACGLYG10_1022 PE=4 SV=1 +-----GQKmlehsQHYVYFPGPECDPMDQAYACLYLASKMGRAVRGQVIQVCNGAF----------------------------- +>tr|A0A239P8M2|A0A239P8M2_9BRAD 3-oxoacyl-[acyl-carrier protein] reductase OS=Tardiphaga sp. OK246 GN=SAMN05216374_6254 PE=4 SV=1 +-----GSVrnrqfi---ALPAARNHTT--egIADIav-ALTCDDRADRSGRDIM-VAGAM------------------------------ +>tr|A0A1Z9UPA9|A0A1Z9UPA9_9BACT Uncharacterized protein OS=Flammeovirgaceae bacterium TMED290 GN=CBE50_06550 PE=3 SV=1 +-----VEAwakr---FGTVSDSGMDVsHVAESICYALSYP----PGVAVDLLEVRP----------------------------- +>tr|A0A143PL72|A0A143PL72_9BACT 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Acidobacteria bacterium DSM 100886 GN=fabG_6 PE=4 SV=1 +VTDAVRRHVGERPDLLHIATPDDVARVITYLVSEEARLITANRVHLR--------------------------------- +>tr|A0A1X7PDT3|A0A1X7PDT3_9MICO 3-oxoacyl-[acyl-carrier protein] reductase OS=Rathayibacter sp. VKM Ac-2121 GN=SAMN06295885_3319 PE=3 SV=1 +VTDEVRESVAQNDHFFDVARPEEVGDLASFLVSPAGRRVTGNVIRMA--------------------------------- +>tr|A0A1Y5F2W7|A0A1Y5F2W7_9PROT Uncharacterized protein OS=Halobacteriovorax marinus GN=A9Q84_19080 PE=4 SV=1 +------ENIKNTIPTGEFVNVEHISGLVDFFLTPASTPINGVTLPVANSMHL---------------------------- +>tr|A0A081BYK1|A0A081BYK1_9BACT Short-chain dehydrogenase/reductase SDR OS=Candidatus Vecturithrix granuli GN=U27_04373 PE=3 SV=1 +--------YSKQLPMGKVGTPEEVARIVVLCSSYIMDPLINQTLNAWWGRG----------------------------- +>tr|A5BPV5|A5BPV5_VITVI Uncharacterized protein OS=Vitis vinifera GN=VITISV_014635 PE=4 SV=1 +--------------F--VNVYSNLKGVSLEMIIKDANP---IGIIISNKS------------------------------ +>tr|A0A1W1ZYQ9|A0A1W1ZYQ9_9RHOB 3-oxoacyl-[acyl-carrier protein] reductase OS=Pseudooceanicola flagellatus GN=SAMN06295998_102258 PE=3 SV=1 +--PEQLNTIKRRTPSGSLSNDENIFKVVDMVISG-TTNMQGQVVFVDGGITS---------------------------- +>tr|A0A1R0WMP7|A0A1R0WMP7_9BACL 3-oxoacyl-ACP reductase OS=Paenibacillus odorifer GN=BSO21_31560 PE=3 SV=1 +--------NEPLPDFWRIGDAEAIASFVTALLRESDADLTGEIFAVNGSKVT---------------------------- +>tr|A0A1Z9BIV6|A0A1Z9BIV6_9BACT Uncharacterized protein OS=bacterium TMED88 GN=CBC48_08115 PE=4 SV=1 +-AE-KEGRPLPSPEELGLGDPADIARVLVFMASDAAQALNAQIVSFNGRKLA---------------------------- +>tr|A4EFJ5|A4EFJ5_9RHOB Short-chain dehydrogenase/reductase SDR OS=Roseobacter sp. CCS2 GN=RCCS2_07259 PE=3 SV=1 +-TLDQVRaEYAKSNPQNQLVQPSEVAELAAFLASDAARALTMEDFQVNAGSLW---------------------------- +>tr|A0A0R2TRQ2|A0A0R2TRQ2_9RHOB Uncharacterized protein OS=Rhodobacter sp. BACL10 MAG-120910-bin24 GN=ABR89_09430 PE=3 SV=1 +-TNAQARaILEKSNPQGRLVQPSEIAAMVDFFCSERSPGLTNVDIQINAGADW---------------------------- +>tr|A0A1Q3QZ68|A0A1Q3QZ68_9BURK 3-hydroxybutyrate dehydrogenase OS=Hydrogenophaga sp. 70-12 GN=BGO22_15310 PE=3 SV=1 +-SREdVVRqL-LVKQPSQDFVTLEQVAALAAYFVSDEAAQTRGVAWNLDGGYAA---------------------------- +>tr|A0A1Q7D6X7|A0A1Q7D6X7_9BACT Uncharacterized protein OS=Candidatus Rokubacteria bacterium 13_1_40CM_68_15 GN=AUH30_13365 PE=3 SV=1 +-SFDeAVAAMAKMNAGGRLIEPGEVAAVAVRCLRDG--GLNGEIVVLDGTEPQ---------------------------- +>tr|A0A1R1J4B6|A0A1R1J4B6_9BURK Short-chain dehydrogenase OS=Burkholderia ubonensis GN=BW685_27805 PE=3 SV=1 +-GAEqFYKDTCAPLELKRFNTPVEVANLVAFLLSDEASGVTGRDWLMHTIWNQ---------------------------- +>tr|A0A1W9HFD1|A0A1W9HFD1_9PROT Short-chain dehydrogenase OS=Proteobacteria bacterium SG_bin7 GN=A4S09_16865 PE=4 SV=1 +-SFEeAFKQQMGLVPLGKWSQPDEIGAYVSYLVSPKQTSITGQALHINNGALM---------------------------- +>tr|A0A0Q7DG89|A0A0Q7DG89_9CAUL Short-chain dehydrogenase OS=Phenylobacterium sp. Root1277 GN=ASC73_06185 PE=3 SV=1 +---EGGQKQMKGFPRRRLMEAEDLDASLLMLCGPAARAITGTVITIDDGQSL---------------------------- +>tr|A0A1T4NMB3|A0A1T4NMB3_9ACTN NADP-dependent 3-hydroxy acid dehydrogenase YdfG OS=Marinactinospora thermotolerans DSM 45154 GN=SAMN02745673_01510 PE=4 SV=1 +---SK-LMADLIERI-DVLSSEDVAETVAFMSAVPkhVNLTEITILPTEQVI------------------------------ +>tr|B6A5H0|B6A5H0_RHILW Short-chain dehydrogenase/reductase SDR OS=Rhizobium leguminosarum bv. trifolii (strain WSM2304) GN=Rleg2_6281 PE=3 SV=1 +---KWVHQM-SAITGFGYGSKADISSVALFLASESSGFISGQNIPVCGLANI---------------------------- +>tr|A0A1S2RBK9|A0A1S2RBK9_9BACI 3-oxoacyl-ACP reductase OS=Bacillus sp. MUM 13 GN=BIV59_01105 PE=4 SV=1 +-------------ADYELADPADIVAVFLYLASEASSQINGQRFMAQNFQKG---------------------------- +>tr|A0A1V5IU70|A0A1V5IU70_9BACT Putative oxidoreductase SadH OS=bacterium ADurb.BinA028 GN=sadH_2 PE=4 SV=1 +--SSTvLPDFR-----ltMDVATPAEVAEMVLAAIEDGLFYLVT---APDAGQWA---------------------------- +>tr|R4LT08|R4LT08_MYCTX Short chain dehydrogenase OS=Mycobacterium tuberculosis str. Haarlem/NITR202 GN=I917_05455 PE=4 SV=1 +-AELVKNMVQT-IPLSRMGXXXGSGGHVTXSLLxvixHRGSPGRSsmSMADRSSGHD----------------------------- +>tr|S8DT73|S8DT73_FOMPI NAD-binding protein (Fragment) OS=Fomitopsis pinicola (strain FP-58527) GN=FOMPIDRAFT_55339 PE=4 SV=1 +----------------------KVLEaFDLLLKPG--SKHSGQCVEAVGDHVAFC-------------------------- +>tr|A0A165GDZ6|A0A165GDZ6_9APHY NAD(P)-binding protein OS=Laetiporus sulphureus 93-53 GN=LAESUDRAFT_711472 PE=3 SV=1 +-PARLFKELVNAPG-MVVSGPEVVASLVSYLAKPESSFITEFDNATELQIH----------------------------- +>tr|A0A0H2R280|A0A0H2R280_9HOMO NAD-binding protein OS=Schizopora paradoxa GN=SCHPADRAFT_910723 PE=4 SV=1 +-QLAAARKLMGLPPNTQSAEPGVVGNVVSFLCKPESHFITGQTISVDGGLV----------------------------- +>tr|B6K3K8|B6K3K8_SCHJY 3-oxoacyl-[acyl-carrier-protein] reductase Oar2 OS=Schizosaccharomyces japonicus (strain yFS275 / FY16936) GN=SJAG_03198 PE=3 S +---------------ERIASVDEVVRAATFLLFDSMCSGNIVPLH----------------------------------- +>tr|A0A1B9T6F3|A0A1B9T6F3_9RHIZ Uncharacterized protein OS=Agrobacterium rubi GN=A6U92_19140 PE=4 SV=1 +---------------SQMVTPEVVVDSVERALEAGrevn--YPGRGKLI----------------------------------- +>tr|A0A1M7MXP4|A0A1M7MXP4_9BURK 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase OS=Rhizobacter sp. OV335 GN=SAMN02787076_02694 PE=4 SV=1 +---------------E----AQDLARTIEWIHRQPahvnvqeiSLFPVAQSLYVRGIHRH---------------------------- +>tr|A0A1Z9ACR9|A0A1Z9ACR9_9EURY Uncharacterized protein OS=Euryarchaeota archaeon TMED99 GN=CBC59_00890 PE=4 SV=1 +---------------GMLCDPEEVVDQIEKDLLTDkiic--YPTKEALY----------------------------------- +>tr|A0A1H6DHR7|A0A1H6DHR7_9ACTN Uncharacterized protein OS=Streptomyces yanglinensis GN=SAMN05216223_115121 PE=4 SV=1 +--PDTQKLAAHAIAQGRIAMPDDTTAMVPAILSEAFQWATGSIIDVSGGQ------------------------------ +>tr|A0A180ER75|A0A180ER75_9BACT Uncharacterized protein OS=Lewinella sp. 4G2 GN=A3850_003505 PE=3 SV=1 +----DINNDRPYLTVRRSGHPTEIASMVKYIASDESSFISGMSYDVDGGMAIGEP------------------------- +>tr|W3XE03|W3XE03_9PEZI Uncharacterized protein OS=Pestalotiopsis fici W106-1 GN=PFICI_02348 PE=4 SV=1 +-GSLDAQAMMNEMATGRFGLPEEVAEAIVWVTSGRASLIVAGHLTPNG-------------------------------- +>tr|A0A1B8F2W5|A0A1B8F2W5_9PEZI Uncharacterized protein OS=Pseudogymnoascus sp. 05NY08 GN=VF21_04360 PE=4 SV=1 +-PDKVKTSV-ATVPMGRMAEMEEVADTDDEKNDPEctnrGLSLAGTihhtaRALEDV-------------------------------- +>tr|A0A1X6PF71|A0A1X6PF71_PORUM Uncharacterized protein OS=Porphyra umbilicalis GN=BU14_0076s0034 PE=4 SV=1 +---RRP---RGGGGGGRPKEPPRLRA---ATAGPRRR------------------------------------------- +>tr|A0A239HW98|A0A239HW98_9ACTN NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Geodermatophilus pulveris GN=SAMN06893096_10975 PE= +--PDRVARVGPTVPMGRAGRAEEVAAPSCGCSATTPATAPAACStspaaaDQCPGR------------------------------ +>tr|A0A0D2AZE8|A0A0D2AZE8_9EURO Uncharacterized protein OS=Exophiala spinifera GN=PV08_09322 PE=4 SV=1 +--PGLREKWESQNLVDFLNQKNtealHYFVSAMLVPS----------------------------------------------- +>tr|A0A072NVS1|A0A072NVS1_9EURO Alcohol dehydrogenase OS=Exophiala aquamarina CBS 119918 GN=A1O9_12414 PE=4 SV=1 +--PHLKGLWEKENMLGRISEPSEYRGAALFCLSDASTFMTGSQVGELsmpvevDTYTVL--------------------------- +>tr|A0A1F8A0M5|A0A1F8A0M5_9EURO Short-chain dehydrogenase/reductase OS=Aspergillus bombycis GN=ABOM_005792 PE=4 SV=1 +--DDVREAFLKTIPTGKFALPEEVADAVLFLCQASISLSRYSYIGTNQLNR----------------------------- +>tr|A0A1F5QRZ1|A0A1F5QRZ1_9BACT Uncharacterized protein OS=Candidatus Eisenbacteria bacterium RBG_16_71_46 GN=A2W00_08290 PE=3 SV=1 +---------------DRNLEPSEIASLVAWICAAPEHVVVGNaTIWPLDaGVSGG--------------------------- +>tr|A0A1S9AM02|A0A1S9AM02_9BURK Short-chain dehydrogenase OS=Massilia sp. KIM GN=B0920_14580 PE=3 SV=1 +---------------IEFLKAEDVAETVGFIVALPKHANIQQvVIMPTKeGM------------------------------ +>tr|L9L2I3|L9L2I3_TUPCH Dehydrogenase/reductase SDR family member 2 OS=Tupaia chinensis GN=TREES_T100008210 PE=4 SV=1 +VARGL-------------------CGTCILPVLPGASDITSEDIVVAGF------------------------------- +>tr|A0A1Y2SU50|A0A1Y2SU50_9GAMM 3-oxoacyl-ACP reductase OS=Xenorhabdus beddingii GN=Xbed_00618 PE=4 SV=1 +-----KRLSVPFHLLeKRLTLARDVAQ-VAFAIHRYFLWVTGDIITVDGGLLLGN-------------------------- +>tr|A0A1H8EP05|A0A1H8EP05_9ACTN NADP-dependent 3-hydroxy acid dehydrogenase YdfG OS=Streptomyces rubidus GN=SAMN05216267_1002275 PE=4 SV=1 +SPEANSGA----------LQPADVADLVAALLAlppHaEVRLLECSSVhSAYG-------------------------------- +>tr|A0A1K1TVI7|A0A1K1TVI7_9BACL NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Thermoactinomyces sp. DSM 45891 GN=SAMN04487866_101 +-----------NYDL---VDPNEVVDVFLHLASAEST-ENGERIQATEflqKRGAL--------------------------- +>tr|D3F395|D3F395_CONWI Short-chain dehydrogenase/reductase SDR OS=Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577) GN=Cwoe_ +-PQAFLAEKTERHPSGRLLAPEDVAEVATFLLEERAIGVNGAALLIDGGLTATFDYQ----------------------- +>tr|A0A0Q8ARN6|A0A0Q8ARN6_9MICO Uncharacterized protein OS=Microbacterium sp. Root166 GN=ASD56_02445 PE=3 SV=1 +-----------NDIVGEPIVPSEITSVMRFVLSDAGSRINAQNIVVDGGYLAGVEF------------------------ +>tr|W2S1H2|W2S1H2_9EURO Uncharacterized protein OS=Cyphellophora europaea CBS 101466 GN=HMPREF1541_03751 PE=4 SV=1 +-RKKIFDMCVGRQCVKRWGLAGDVARTVCWIAGPETEFVTGQGFDVGGGTL----------------------------- +>tr|A0A1I5Y6D1|A0A1I5Y6D1_9ACTN 3-oxoacyl-[acyl-carrier protein] reductase OS=Actinomadura madurae GN=SAMN04489713_13035 PE=4 SV=1 +-ADGAFERVRDLQIVPAVEEPRDLVSTLLYVCDEGSGFLTGQTINVDGGSA----------------------------- +>tr|A0A0F4Z1Q2|A0A0F4Z1Q2_TALEM Oxidoreductase, short-chain dehydrogenase/reductase family OS=Rasamsonia emersonii CBS 393.64 GN=T310_1476 PE=4 SV=1 +-SEATLRTVAAFSPFNRIAQPDEMAGTIAFLCGPDTRKnISAEYVRISQ-------------------------------- +>tr|X1I0S6|X1I0S6_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S03H2_46067 PE=4 SV=1 +----------RNLAYSKTEELERSSKIALEKAAAqgagiiedNDKIMTCSY-SSTIKEVFRIAHR----------------------- +>tr|A0A1R1HV49|A0A1R1HV49_PAEMA 3-ketoacyl-ACP reductase OS=Paenibacillus macerans GN=BK140_07015 PE=4 SV=1 +---------------DRMMQPEDVAELITATLKlPQRVFIKSAGIWTTNPQ------------------------------ +>tr|A0A0D1Z3J6|A0A0D1Z3J6_9EURO Uncharacterized protein OS=Exophiala mesophila GN=PV10_08927 PE=4 SV=1 +-PREVFDHIKGVTPLRKVTTPDDLAGAVLFFCQSmgkWHHRTAArgrwwtrDELMAPGRIF----------------------------- +>tr|I5BWS7|I5BWS7_9BACT 3-ketoacyl-(Acyl-carrier-protein) reductase OS=Nitritalea halalkaliphila LW7 GN=fabG PE=3 SV=1 +-SDAVFDIIQANTPLQRVTSLKNWPMpacf--LHLPGHAPSPVRT--------------------------------------- +>tr|A0A1A1YAL3|A0A1A1YAL3_9MYCO Uncharacterized protein OS=Mycobacterium sp. ACS1612 GN=A5724_28595 PE=4 SV=1 +--------IASQVAWLAfVNAAEVTGTVVRvdcdgSVVSAPAVW------------------------------------------ +>tr|N1S4B2|N1S4B2_FUSC4 Trihydroxynaphthalene reductase OS=Fusarium oxysporum f. sp. cubense (strain race 4) GN=FOC4_g10001350 PE=4 SV=1 +GDKmsieEVDGEISEISPLGRPGFPMTLQELLPCWQALrrngsLVRRSTQAVELIWGTQGG---------------------------- +>tr|A0A1M5PHJ9|A0A1M5PHJ9_9EURY 3-oxoacyl-[acyl-carrier protein] reductase OS=Halobaculum gomorrense GN=SAMN05443636_1605 PE=4 SV=1 +IVEhleatgfLGHENVDTHLP-EYSCSPEEVARSVAYLVD--SEFTHGEVHSVNGGMHF---------------------------- +>tr|A0A1L3ZWB8|A0A1L3ZWB8_9SPHN Uncharacterized protein OS=Sphingomonas sp. JJ-A5 GN=BSL82_11745 PE=4 SV=1 +--AEV---gtgyVPPALRAVGTSEPTrHLAPLVAFFASPEGGLVTGQTVIADGGAWMLP-------------------------- +>tr|A0A1Q8A7G8|A0A1Q8A7G8_9CHLR Uncharacterized protein OS=Chloroflexi bacterium 13_1_20CM_2_70_9 GN=AUG02_06870 PE=3 SV=1 +--PTA---dfprsdeYRAAQREGKLKDPAVPARAIAYLAMPSTHRNGAVLEWSDESLRTEV-------------------------- +>tr|A0A226Y739|A0A226Y739_9BURK Oxidoreductase OS=Achromobacter sp. KAs 3-5 GN=BMR85_009075 PE=4 SV=1 +--PRLRRQsvtprklldqrgpmtilrLRQRLQVGRAGRIRgHA------------RVQHG-ADVGDGG------------------------------- +>tr|A0A136MSV6|A0A136MSV6_9BACT 3-oxoacyl-(Acyl-carrier-protein) reductase FabG OS=Omnitrophica bacterium OLB16 GN=fabG_2 PE=3 SV=1 +------GLYL---------HAADLAQTIVFLSKLPGRTLVRDMDVWGtnpgr--------------------------------- +>tr|A0A0W0ZGS2|A0A0W0ZGS2_9GAMM 3-oxoacyl-[acyl-carrier-protein] reductase OS=Legionella steelei GN=Lste_1398 PE=4 SV=1 +------REFMPDKPDDFFVKPNDVAETVFWLTQQAPSTWSFEVEIRPFG-EV---------------------------- +>tr|R1GIW7|R1GIW7_BOTPV Putative short-chain dehydrogenase reductase sdr protein OS=Botryosphaeria parva (strain UCR-NP2) GN=UCRNP2_1598 PE=4 SV=1 +-------VVKGPEFVKRMEQGNSLGReMRTYVALA--------ENVV---------------------------------- +>tr|A0A0U1HT07|A0A0U1HT07_YERRO 3-ketoacyl-ACP reductase OS=Yersinia rohdei GN=fabG_4 PE=4 SV=1 +------EKIVSQQIIPKQFTPEAVSDLIEILFDARSSSLSGQILHIGGV------------------------------- +>tr|A0A1F9YC32|A0A1F9YC32_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RIFOXYB2_FULL_49_7 GN=A2293_11655 PE=3 SV=1 +--------QRKQSLLGAINAVE-TSARFVYWLSE-ATWGTGRIFDCDGREYK---------------------------- +>tr|A0A1F8ASD3|A0A1F8ASD3_9BACT Uncharacterized protein OS=Candidatus Woesebacteria bacterium RIFCSPHIGHO2_12_FULL_41_24 GN=A3E44_02795 PE=3 SV=1 +------GK--------AYFPVEWVANKLVEILKDDKR--QTETVLYPgdHGFGI---------------------------- +>tr|A1TE18|A1TE18_MYCVP Short-chain dehydrogenase/reductase SDR OS=Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) GN=Mvan_4643 PE=4 SV=1 +---GVVEDYVDNTVLGRAGTAEDIANAVVYLCAPGSSWLTGEVLDINGGAHLKRYP------------------------ +>tr|A0A1J4TX26|A0A1J4TX26_9HELI Uncharacterized protein OS=Helicobacteraceae bacterium CG1_02_36_14 GN=AUJ81_04115 PE=4 SV=1 +---ELYNLYRSISPSKSVLKSSNVVDLAKYLLFKKSKFITGQNIIIDGGISLQW-------------------------- +>tr|A0A1N6J2J6|A0A1N6J2J6_9BURK L-rhamnose 1-dehydrogenase OS=Paraburkholderia phenazinium GN=SAMN05444165_2728 PE=4 SV=1 +---DKRAYFEQRIPLGRLGEPDDVADSAAEIDVLK-------VVHVEAIHDAWTSP------------------------ +>tr|A0A1V6EWP9|A0A1V6EWP9_9BACT Putative ketoacyl reductase OS=Candidatus Cloacimonetes bacterium ADurb.Bin089 GN=actIII PE=4 SV=1 +-SGEYlnfrkryFAEYLAQAPTGKLVTKEEIKKVIDLLIDESITTLNGQEIIIGGGI------------------------------ +>tr|A0A1E7YXV5|A0A1E7YXV5_9PROT Oxidoreductase OS=Acidithiobacillus caldus GN=BAE30_05230 PE=4 SV=1 +-PEEAMRQRRQE--L-DALHPEDVAQALVYSFAQPPHVLVEEILVRPVKQIV---------------------------- +>tr|A0A1N6CKY3|A0A1N6CKY3_9MYCO Short-chain dehydrogenase OS=Mycobacterium abscessus subsp. abscessus GN=fabG_19 PE=4 SV=1 +-SEAELAAITEDLPQQRLIDPTEIAHTCSYLCHPFAKSITGTIQKVNGAWYL---------------------------- +>tr|M5RGJ4|M5RGJ4_9PLAN 3-oxoacyl-(Acyl-carrier protein) reductase OS=Rhodopirellula maiorica SM1 GN=RMSM_04555 PE=4 SV=1 +----WDGRARNQSLMNRWGTPEDVARAIAFVSDPENSFFSGQVVQVNGGWNRNYIHR----------------------- +>tr|Q0CLZ1|Q0CLZ1_ASPTN Uncharacterized protein OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=ATEG_05293 PE=4 SV=1 +----ARRILDHNCPMGCMGSSDDVANGVVWLSSGASRYVTSHALVIDGGITESTG------------------------- +>tr|T0GTY7|T0GTY7_9SPHN Uncharacterized protein OS=Sphingobium baderi LL03 GN=L485_05485 PE=4 SV=1 +---DLAERIRGALALPRFGQRIDIGNAVAWLCSEAASFVTGTTIDCDGGMRLGNL------------------------- +>tr|A0A1V2IK14|A0A1V2IK14_9ACTN Short-chain dehydrogenase OS=Frankia sp. M16386 GN=BL253_01850 PE=3 SV=1 +---GEhthlvWPRLQAEGtinrVIGKHGgmTVESVADVHIFIATRPR----GQKLDVVRARSY---------------------------- +>tr|B9EBG7|B9EBG7_MACCJ Uncharacterized protein OS=Macrococcus caseolyticus (strain JCSC5402) GN=MCCL_0871 PE=4 SV=1 +--DDVE-SIIEQIPQKKCVQPVEISHFVRALLHQYSHTTTGTVIRINGGWYI---------------------------- +>tr|A8SQL8|A8SQL8_9FIRM Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Coprococcus eutactus ATCC 27759 GN=COPEUT_00529 PE=4 SV=1 +---DAFKANVKMPPMGHFGDVEkEIGRACVALASPDFKYMSGETITLEGAMGQ---------------------------- +>tr|A0A0F4YLI5|A0A0F4YLI5_TALEM 2-(S)-hydroxypropyl-CoM dehydrogenase OS=Rasamsonia emersonii CBS 393.64 GN=T310_7066 PE=4 SV=1 +---RIFENTMEWYPLKRAIEPEDVANAVAFLASPQAAAITGIRLNEYKFVNLTLTDI----------------------- +>tr|A0A1Z5S7Q4|A0A1Z5S7Q4_SORBI Uncharacterized protein OS=Sorghum bicolor GN=SORBI_3001G264100 PE=4 SV=1 +-----RDNILSRAPLRRAGEPEEISSIVAFLCMPGSTYtatRSGRACCPGSRagAALPGLKA----------------------- +>tr|A0A1X1YZB1|A0A1X1YZB1_MYCNO Short-chain dehydrogenase OS=Mycobacterium nonchromogenicum GN=AWC18_18520 PE=4 SV=1 +------EWLARSLVQARQMTPEAVADTLAGIF-------AAAIEQPDVSLES---------------------------- +>tr|A0A1H7FNL0|A0A1H7FNL0_STIAU 2-keto-3-deoxy-L-fuconate dehydrogenase OS=Stigmatella aurantiaca GN=SAMN05444354_10195 PE=4 SV=1 +--PGMRASLVANIPAGRTGEGYEAAELALSLATNASNFMAGQVISMAGGWCT---------------------------- +>tr|A0A1U6J1Y6|A0A1U6J1Y6_9MICC 3-oxoacyl-[acyl-carrier protein] reductase OS=Arthrobacter sp. P2b GN=SAMN06272721_12047 PE=4 SV=1 +--PEYMDEIKRMVPMGRFGSPSEVGALIGAVTSGEMQFVSGQVIAFSGAGC----------------------------- +>tr|A0A1G3K7L2|A0A1G3K7L2_9SPHN Uncharacterized protein OS=Sphingopyxis sp. RIFCSPHIGHO2_01_FULL_65_24 GN=A2885_02830 PE=4 SV=1 +---ARTALVGEFHPSRQMVSPEQIADAVAWAAAPGGAHATGLTIPIDGGWSA---------------------------- +>tr|A0A1F9ULZ6|A0A1F9ULZ6_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_59_12 GN=A2992_01980 PE=4 SV=1 +-SEEQRERVTAEHALGHTTQIEDLTRLVMEVAQ--NTSVSGQIFNIDSRV------------------------------ +>tr|A0A1F9DS51|A0A1F9DS51_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RBG_16_55_12 GN=A2W10_08930 PE=4 SV=1 +-------------ARGRLPGPEILGN-GFVLAAQLPMEQSGRLFEYQDGKLV---------------------------- +>tr|A0A0S4QP12|A0A0S4QP12_9ACTN Acetoacetyl-CoA reductase OS=Frankia sp. G2 GN=Ga0074812_10852 PE=4 SV=1 +MPEPIKDAWLDSLPNG-FVDPDDIANAVAFFAAPESAMVTGQLLTVDGGDALNTRSV----------------------- +>tr|A0A235G8G2|A0A235G8G2_9NOCA 3-oxoacyl-[acyl-carrier protein] reductase OS=Rhodococcus sp. OK302 GN=BDB13_3041 PE=4 SV=1 +MPAETRDRVLRNVAMKRLVEVNEVVASVLFLMSSGAGAITGQSLRVDGGAGINTQGL----------------------- +>tr|A0A1U8JLB6|A0A1U8JLB6_GOSHI tropinone reductase homolog At2g29260, chloroplastic-like isoform X2 OS=Gossypium hirsutum GN=LOC107906578 PE=4 SV=1 +--NRSLvikqcpsS-----------------NGSVSWYCESEFAKFQDKLQANDT-------------------------------- +>tr|N1LQL4|N1LQL4_9BACI 3-oxoacyl-[acyl-carrier protein] reductase OS=Bacillus sp. GeD10 GN=EBGED10_37560 PE=4 SV=1 +---NGKNFIKRFIPTKKLVDKNHLGYLLTYLSSDFSTSITGAAITVDRGHSI---------------------------- +>tr|C1H9Z2|C1H9Z2_PARBA 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase OS=Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) GN=PAAG_07721 PE +----FVERRHKAVPMGGMGDSFDVAYSVAFWLLNRRSISLDRRSLWIGELLHPL-------------------------- +>tr|A0A1G0E8G7|A0A1G0E8G7_9GAMM 3-ketoacyl-ACP reductase OS=Gammaproteobacteria bacterium RBG_16_37_9 GN=A2V89_02635 PE=4 SV=1 +--KEYNDWVIDKQCLKTRIHPEHVANLIVFLSGPKSDYITAQNIGIDAGW------------------------------ +>tr|G4TJW2|G4TJW2_SERID Related to 3-oxoacyl-[acyl-carrier-protein] reductase OS=Serendipita indica (strain DSM 11827) GN=PIIN_05541 PE=4 SV=1 +-SSDVMNTMKQANPYKKLGDPKDIALAVEGIL-VSGKWLNGSNIRANGGSA----------------------------- +>tr|A0A149QGT3|A0A149QGT3_9BURK Uncharacterized protein OS=Burkholderia megalochromosomata GN=CR51_22955 PE=3 SV=1 +--------RADSVPMRWQG---EGGTLVRTQ-HSLHRMTHDSSLGRYSPWTV---------------------------- +>tr|A0A1C1XMV5|A0A1C1XMV5_9PEZI Uncharacterized protein OS=Diaporthe helianthi GN=DHEL01_06212 PE=4 SV=1 +--------RVEQNLLGTEGTGWDVGYGETDRPGSSSKaeFTRRPNGRASG--SAG--------------------------- +>tr|A0A1U8HVQ0|A0A1U8HVQ0_GOSHI 3-oxoacyl-[acyl-carrier-protein] reductase 4-like OS=Gossypium hirsutum GN=LOC107887677 PE=3 SV=1 +------KRILTTIPFGRYGQPAEEYEVVSYQTSrELNCFIPSKSERTTESVIS---------------------------- +>tr|S3BPQ4|S3BPQ4_9ACTN Uncharacterized protein OS=Streptomyces sp. HPH0547 GN=HMPREF1486_05706 PE=4 SV=1 +--QAVRQRLDARMALPRMAEDGDVAETVAFFASARSRGITGQCLMVNAGELM---------------------------- +>tr|A0A173KZW8|A0A173KZW8_9SPHN 3-oxoacyl-[acyl-carrier-protein] reductase OS=Sphingobium sp. EP60837 GN=EP837_03405 PE=4 SV=1 +--EDVVAGVTKNIPIGIIPPEDDCARAVLMMVSDYSRVVSGAALDVNGGQWM---------------------------- +>tr|A0A0C1RDR3|A0A0C1RDR3_9ACTN Uncharacterized protein OS=marine actinobacterium MedAcidi-G2A GN=MB53_01975 PE=4 SV=1 +--QEEYDNVADEIALRYIPDSEQICGSVVFFASDLSIACTGTSLDVNGGHFM---------------------------- +>tr|A0A1A3PMG4|A0A1A3PMG4_9MYCO Uncharacterized protein OS=Mycobacterium sp. 1245111.1 GN=A5658_07735 PE=4 SV=1 +--ADVRAEYASALALGRIPTGAEYADVAVFLLSELSRAVSGHVLDANGGEYF---------------------------- +>tr|A0A0M3CHM1|A0A0M3CHM1_9SPHI 2-deoxy-D-gluconate 3-dehydrogenase OS=Sphingobacterium sp. IITKGP-BTPF85 GN=L950_0201165 PE=4 SV=1 +--PQLAAEAQNHVPVQALIESEEVAKQICWMCLPENRHLTGSTILMDGGLSLM--------------------------- +>tr|A0A063B258|A0A063B258_9BURK 3-oxoacyl-(Acyl-carrier-protein) reductase OS=Burkholderia sp. lig30 GN=LIG30_4275 PE=4 SV=1 +----HGRFWEAHSTLRRVGSAAEVASAVMFFAQPEAAYINGTCLPVTSALDW---------------------------- +>tr|A0A0N9R355|A0A0N9R355_CEV01 Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR) OS=Chrysochromulina ericina virus GN=ceV_146 PE=4 SV=1 +---LFKYYNNYINPSKRMCHPDEIADLSLYLTSVKADYINGEIIKIDGGEYIKNSG------------------------ +>tr|G3NFB8|G3NFB8_GASAC Uncharacterized protein OS=Gasterosteus aculeatus GN=ABCC6 PE=4 SV=1 +---EFEKAMIGRIPTGRLGTPTEVSNLAAYISSDYATWMSGAENNEFL-------D------------------------ +>tr|A0A062XUG1|A0A062XUG1_9BACT Uncharacterized protein OS=Thermoanaerobaculum aquaticum GN=EG19_12165 PE=4 SV=1 +---AVQALLAKKVPLRRLASTEEVAFLACDLVTDRHPYVTGDCWTVDGGLWLEGFP------------------------ +>tr|A0A1J5TQS9|A0A1J5TQS9_9EURY Uncharacterized protein OS=Marine Group III euryarchaeote CG-Epi3 GN=BEU00_03375 PE=4 SV=1 +---KTAKMFENYIPLGGVTDSNKMAQQVLYLCSSAADVITGDMLIADGGQWLVGNA------------------------ +>tr|E1YM73|E1YM73_9DELT 3-oxoacyl-[acyl-carrier-protein] reductase OS=uncultured Desulfobacterium sp. GN=N47_E47180 PE=3 SV=1 +------------RYDGRIMTTEDAAYPILFFARDESWCINGNCLQAALGGF----------------------------- +>tr|A0A1F8QVL9|A0A1F8QVL9_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_57_8 GN=A2147_07685 PE=4 SV=1 +-------GQEIKIDMSKLAMPEELAEAVLFLVSSGSDHMSGQNIIFGVPMA----------------------------- +>tr|G3WQX4|G3WQX4_SARHA Uncharacterized protein OS=Sarcophilus harrisii PE=3 SV=1 +--------HRAIIKIKNTKIKRVISSITCFLLSPAAGHIVNAD----CGNTSFPNL------------------------ +>tr|S2EUB1|S2EUB1_9PSED Uncharacterized protein OS=Pseudomonas sp. G5(2012) GN=PG5_48340 PE=4 SV=1 +--PERLEQILKMIPAGTLGDPAFIADSVLLLIADNATSVTGACLDVNGGLFMR--------------------------- +>tr|A0A1K2CCU9|A0A1K2CCU9_9PSED Meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase OS=Pseudomonas sp. NFPP16 GN=SAMN03159327_5 +---DLWARMEGLIPLGRTQIPENIARFCLAVLEN--EDITAQSLSVDGGMNLY--------------------------- +>tr|A0A1C2FWM5|A0A1C2FWM5_9PROT Short-chain dehydrogenase OS=Campylobacter sp. WBE38 GN=A7X81_00945 PE=4 SV=1 +-----DLNAIQQFYPLGIGKVENISPLICFLLSKGSSWITGQNFVIDGGGGI---------------------------- +>tr|G9PRR8|G9PRR8_9BACT Uncharacterized protein OS=Synergistes sp. 3_1_syn1 GN=HMPREF1006_02840 PE=4 SV=1 +-AGDMRKAIIDQHFFGRIAETDDFLGAAIFLSSDASNYVTGHVLAVDGGWSVSKPW------------------------ +>tr|A0A136J8J5|A0A136J8J5_9PEZI Short chain dehydrogenase OS=Microdochium bolleyi GN=Micbo1qcDRAFT_223091 PE=4 SV=1 +-KEAlkpfnkltplgkarpgidtq--EMVSLAEdIGCRPGYLDEVAGIVGIACLPESGWMTGTVMGANGGGAF---------------------------- +>tr|M7SC21|M7SC21_EUTLA Putative 3-ketoacyl-acyl carrier protein reductase protein OS=Eutypa lata (strain UCR-EL1) GN=UCREL1_9302 PE=4 SV=1 +-PGEIIAMQKASTpIENRLGSVKEIADIVAMLAGRDGAWITGQAISASGLGYV---------------------------- +>tr|A0A1X0H2K5|A0A1X0H2K5_9MYCO Oxidoreductase OS=Mycobacterium monacense DSM 44395 GN=BST34_12235 PE=4 SV=1 +-PGS-LEKM-NAAtPLRRLGDVADLGRLCVYLSTRDC-YATNAIFHVDGGIES---------------------------- +>tr|B7RT61|B7RT61_9GAMM Oxidoreductase, short chain dehydrogenase/reductase family OS=marine gamma proteobacterium HTCC2148 GN=GPB2148_2902 PE=4 SV=1 +--SAIREAYERQSSMRMFVEPQDVANMALFLSSSLGSAISGQAIGIDGHTEGLAN------------------------- +>tr|A0YBG0|A0YBG0_9GAMM Short chain dehydrogenase OS=marine gamma proteobacterium HTCC2143 GN=GP2143_05550 PE=4 SV=1 +--DTIRDVYQRQTSLRQFVDAQDIADMALYLSSAAGAMISGQSMAIDGHTESLSN------------------------- +>tr|A0A1M6W645|A0A1M6W645_9BRAD NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Bradyrhizobium lablabi GN=SAMN05444159_4463 PE=4 SV +--AEMERTAFSYTSIKDYVTPEQIADQILFMCSPRGKTISGQAISICGDTQMLG-------------------------- +>tr|A0A1W6BHR5|A0A1W6BHR5_9PROT Short-chain dehydrogenase OS=Candidatus Pelagibacter sp. RS40 GN=B8063_05060 PE=4 SV=1 +--KKIEKEFISMASMNCWIYEEDIGKTCSFLMSDDAARVSGQIIAVDGNAI----------------------------- +>tr|A0A0F8A3S3|A0A0F8A3S3_9HYPO Uncharacterized protein OS=Hirsutella minnesotensis 3608 GN=HIM_08255 PE=4 SV=1 +-----TQSVSSISPLRTVAAPQDVGKVVAFLSHSDSEWINGQIIPTCGALS----------------------------- +>tr|A0A093V214|A0A093V214_TALMA Versicolorin reductase OS=Talaromyces marneffei PM1 GN=GQ26_0180680 PE=3 SV=1 +------GVAHHYIPGGEKYSPEELQQGSN--------------IDFP--------------------------------- +>tr|A0A158SPX3|A0A158SPX3_9SPHN Putative oxidoreductase with NAD(P)-binding Rossmann-fold domain OS=Novosphingobium sp. KN65.2 GN=yjgI PE=4 SV=1 +---PMAATMHSFMAIKRHVRPAEIAELTAYIAGPHGAMITGSMQTIDGAFG----------------------------- +>tr|A0A1W5CW33|A0A1W5CW33_9LECA Nad-binding protein OS=Umbilicaria pustulata PE=4 SV=1 +---KIEKAMADHNPLRRCALPVDVARVVGFLASQDGEWVNGKFGLHLSSSA----------------------------- +>tr|D2PNP6|D2PNP6_KRIFD Short-chain dehydrogenase/reductase SDR OS=Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399) GN=Kfla_1804 PE=4 SV=1 +-PQAALEHLGQQFTARRLPEAADVAAAIMFLCSARTTATQGEILRVNGGS------------------------------ +>tr|A0A1V2QN86|A0A1V2QN86_9PSEU Short-chain dehydrogenase OS=Saccharothrix sp. ALI-22-I GN=ALI22I_14365 PE=4 SV=1 +-PEFVVSALASATPTRRLSDSDDVARIVVFLGSAANGNLTGELIRDGSSA------------------------------ +>tr|A0A1W6YPS3|A0A1W6YPS3_9BORD Uncharacterized protein OS=Bordetella genomosp. 8 GN=CAL12_20790 PE=4 SV=1 +-PNL---------ARESLLSPEVMVSPLRWLLSKAADNVTCRRIRANLWD------------------------------ +>tr|A0A0M2NDB5|A0A0M2NDB5_9FIRM Short-chain dehydrogenase/reductase SDR OS=Catabacter hongkongensis GN=CHK_2241 PE=3 SV=1 +---DG--VDVDNMDKSGWQKPIDIAKAVMYFADNDNDQVSGNFLSVRGVNQWI--------------------------- +>tr|A0A158B8T6|A0A158B8T6_9BURK Short-chain dehydrogenase/reductase SDR OS=Burkholderia arationis GN=AWB81_02614 PE=4 SV=1 +---KAFTKAEQRVKFK-LNTAEDLAEYILYLSSRESDQVSGSTLSINGGLSFP--------------------------- +>tr|A0A0D1X5E2|A0A0D1X5E2_9EURO Uncharacterized protein OS=Exophiala sideris GN=PV11_04986 PE=4 SV=1 +-------PMLDATPmGSRLAEPSEIAHAIAFLCERRSGWITGAYYDDYKHASV---------------------------- +>tr|W9AT06|W9AT06_9MYCO Short-chain dehydrogenase/reductase SDR OS=Mycobacterium cosmeticum GN=BN977_03744 PE=4 SV=1 +-------ALVTRNHaFGRVGEPTDIGDAICAITARSAGWITAQRIEASGGQSL---------------------------- +>tr|A0A1Y5P2I7|A0A1Y5P2I7_9MICO Putative Short-chain dehydrogenase/reductase SDR OS=uncultured Microbacterium sp. GN=MIPYR_20192 PE=4 SV=1 +-----ARgeapaAAGTTLVKGvavREAQLTDVVDVLMFLA-DGPDSVSGVTIRLDGGRVH---------------------------- +>tr|A0A0E3VWU8|A0A0E3VWU8_9BRAD Putative oxidoreductase OS=Bradyrhizobium diazoefficiens GN=NK6_8386 PE=4 SV=1 +---ELNKQVAGMTALGRAGAPDDIGPMIASLLSDDNRWVNAQRIEVSGAWRFSLPGG----------------------- +>tr|A0A1E5L623|A0A1E5L623_9FIRM Uncharacterized protein OS=Firmicutes bacterium MLFW-2 GN=BHU72_02005 PE=4 SV=1 +-----REIDHLQHFSQRVGKPDDIASACIYLTHGSNDFILGTNLVIDGGMTKK--------------------------- +>tr|A0A1B6Z4Z8|A0A1B6Z4Z8_9SPHN Uncharacterized protein OS=Sphingomonadales bacterium EhC05 GN=A8B75_01805 PE=4 SV=1 +------------ADAG--MKAKDLATAVFHIVDQGPQGETGRSYFFgfSGTPRNQ--------------------------- +>tr|A3PE87|A3PE87_PROM0 Uncharacterized protein OS=Prochlorococcus marinus (strain MIT 9301) GN=P9301_14391 PE=4 SV=1 +------DQRATLIPVGRLADPKEIAKCCYQICSLDNTFQTLSNITIAGGE------------------------------ +>tr|K0EJ50|K0EJ50_9NOCA 3-oxoacyl-ACP reductase OS=Nocardia brasiliensis ATCC 700358 GN=O3I_007150 PE=4 SV=1 +-NPNLLAAMEQMVPLGRGGTPEEAAGAVYLFCIPESDYVSGQTLVCGGGFN----------------------------- +>tr|A0A221VZY9|A0A221VZY9_9PSEU General stress protein 39 OS=Actinoalloteichus hoggarensis GN=ydaD2 PE=4 SV=1 +-PAEKVKEFGKQVPFEEAAHPDDLAPSYVFLASNrLSGYYSGEVIAALGGETT---------------------------- +>tr|A0A165RSL1|A0A165RSL1_9HOMO NAD(P)-binding protein OS=Neolentinus lepideus HHB14362 ss-1 GN=NEOLEDRAFT_1067905 PE=4 SV=1 +------SKVGHIIPIGRIGSEEDTVGTIVYLASRAGSYVSGTCIAVSILTWDG--------------------------- +>tr|A0A066VLF9|A0A066VLF9_9BASI NAD(P)-binding protein OS=Tilletiaria anomala UBC 951 GN=K437DRAFT_258369 PE=3 SV=1 +------------GESGDS-----LIFVPVFASSRTRVH---TTFSVHRPLGLA--------------------------- +>tr|A0A1X9NJJ9|A0A1X9NJJ9_9GAMM Uncharacterized protein OS=Oceanicoccus sagamiensis GN=BST96_13600 PE=3 SV=1 +----AKDYTIAHSAIAQVPTPVDIANSLVSVIT-GSDLMTGQIITIDSGYT----------------------------- +>tr|A0A0C1ZC86|A0A0C1ZC86_9DELT Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Enhygromyxa salina GN=DB30_05726 PE=4 SV=1 +--DRVKAVHDRMFPARRMNTMDEVAALVSVLADDAGYWFNSAVIDFTGGQMH---------------------------- +>tr|A0A090PTB4|A0A090PTB4_9FLAO Oxidoreductase OS=Nonlabens ulvanivorans GN=JCM19298_559 PE=4 SV=1 +--EALKEMSLKRNPNHRLTQPVDVANTVYLLALKSLNGLQVMLLKLMVVNHY---------------------------- +>tr|H1XVE2|H1XVE2_9BACT Short-chain dehydrogenase/reductase SDR OS=Caldithrix abyssi DSM 13497 GN=Calab_2088 PE=4 SV=1 +--ETMIDLALSQIPFKRLTQPSDIAKFILALATSDELWATGNVFNVDGGEVI---------------------------- +>tr|A0A0A8UL66|A0A0A8UL66_LEGHA Enoyl-[acyl-carrier-protein] reductase [NADPH] OS=Legionella hackeliae GN=fabL PE=4 SV=1 +--QQLLDEYHAHSLSAEPLTAADVADVIYLLCRPEAKMINAHTLFVDAGYSQ---------------------------- +>tr|A0A0B6ZXM4|A0A0B6ZXM4_9EUPU Uncharacterized protein OS=Arion vulgaris GN=ORF86317 PE=4 SV=1 +------QELGRRAPIRRMGSKTEIAEICLFLVTDMAGLITSSTIEADGAHWLSDGSE----------------------- +>tr|A0A1S2WR18|A0A1S2WR18_MYCMA Short-chain dehydrogenase (Fragment) OS=Mycobacterium malmoense GN=BMG05_01445 PE=4 SV=1 +------IEDlyrrglldeMTMRASLDAAPAAFVAPLYAYLASDLARDVTGQIFVAAGGFVGSLDRP----------------------- +>tr|A0A0A1MJF4|A0A0A1MJF4_9BACI 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Oceanobacillus oncorhynchi GN=fabG_6 PE=4 SV=1 +-PSWRKEEYLHSELVDTPVTAKDVAETVVFLLSDKSKHYTGATFDINNGGYL---------------------------- +>tr|A0A023C7R0|A0A023C7R0_9PSED Dehydrogenase OS=Pseudomonas extremaustralis 14-3 substr. 14-3b GN=PE143B_0119735 PE=4 SV=1 +-PEYRRAEYARQEILKDPILPSGVAEVIVLLIGESLRHMTGKVIAVDNGAYP---------------------------- +>tr|W5YQ57|W5YQ57_9ALTE Short-chain dehydrogenase OS=Marinobacter salarius GN=AU15_05765 PE=3 SV=1 +--ENQRQQVMSETLLACEGGFDAVVIQLLALLD--NDFITGAQIPVDGGRRLA--------------------------- +>tr|A0A1W6GTJ6|A0A1W6GTJ6_RHIET Short-chain dehydrogenase/reductase SDR family protein OS=Rhizobium etli Brasil 5 GN=Bra5_PD00539 PE=4 SV=1 +-----AQDYRDNVAM----PARDIAEVIAFALSRPKRITLNEILV-RPTVQAM--------------------------- +>tr|A0A0E0L8Q4|A0A0E0L8Q4_ORYPU Uncharacterized protein OS=Oryza punctata PE=4 SV=1 +--EERVVAVAGECPMGRIGEPMDVAPVVASSAAMPPGGSTAKSFVsMAATSK----------------------------- +>tr|A0A1B6AHY7|A0A1B6AHY7_9ACTN Putative oxidoreductase OS=Streptomyces sp. NBRC 110611 GN=SSP35_04_01830 PE=4 SV=1 +--GEVSDQIIRAINdgfrTDWLKAPRTVAEWIVSIAEFPSNGPTGQVFNYSRKVL----------------------------- +>tr|A0A1Q7PLW9|A0A1Q7PLW9_9BACT Uncharacterized protein OS=Nitrospirae bacterium 13_1_40CM_2_62_10 GN=AUI21_04375 PE=4 SV=1 +----------DEILRSEKISPYDIAETAVYLATLGPYAVVHQLIVDR-LGA----------------------------- +>tr|A0A0S4MTD2|A0A0S4MTD2_9BACT NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Candidatus Kryptobacter tengchongensis GN=JGI3_0222 +-------------ENADMLHPRHVAPVAAFLLSDLSREINGTMIVVYGTKLFTYHIV----------------------- +>tr|X1R5W9|X1R5W9_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S06H3_53840 PE=4 SV=1 +-----------------KPDPDFVAPIVVYLTTDTLLAIFTRIRIQPK------RSP----------------------- +>tr|A8XET0|A8XET0_CAEBR Protein CBG12121 OS=Caenorhabditis briggsae GN=CBG12121 PE=3 SV=1 +--------IEICHKhRGNvKNNTEKINVSL------qSSLFR----------------------------------------- +>tr|A0A1Y1UNK0|A0A1Y1UNK0_9TREE Uncharacterized protein OS=Kockovaella imperatae GN=BD324DRAFT_622000 PE=4 SV=1 +-TKESLESFGVTTAIGRAGQPVEIATAFVWLASAESSYYTAQCMHLNGGQAY---------------------------- +>tr|V7L3V0|V7L3V0_MYCAV Oxidoreductase OS=Mycobacterium avium subsp. avium 10-9275 GN=O972_13565 PE=4 SV=1 +--AEEQSQWPRWVPVGRMGLPEDQARVILFLVSDCSSFITGHTIPTDGGTIAAGGWF--RSSRR---------------- +>tr|A0A0C5XGA8|A0A0C5XGA8_9SPHN Uncharacterized protein OS=Sphingobium sp. YBL2 GN=TZ53_05845 PE=4 SV=1 +---KSVDTLIANMAMPRLADPVeDVGGAAMFLVSDEACFILGHRVLADGGQHLTAA------------------------- +>tr|G6Y5R4|G6Y5R4_9RHIZ Short-chain dehydrogenase/reductase SDR OS=Mesorhizobium amorphae CCNWGS0123 GN=MEA186_06368 PE=4 SV=1 +---PAaaPRARSASAPTCRQSGwaRRRSSARSAPSCARSTGYLTGQNIPFDGGPYV---------------------------- +>tr|A0A163V4S0|A0A163V4S0_9FLAO Uncharacterized protein OS=Myroides marinus GN=AV926_02100 PE=4 SV=1 +----IDASMIANIPMGRAGYPEDFEAIAVYFCSDASSFHTGDTVILDGADHIKG-------------------------- +>tr|W9BZY3|W9BZY3_9SPHN 2-deoxy-D-gluconate 3-dehydrogenase OS=Blastomonas sp. CACIA14H2 GN=Q27BB25_00100 PE=4 SV=1 +----FQDGCRRRAASGSIGQLQDMEGIAVYLASQQSNFMTGQALVLDGGHTIFPL------------------------- +>tr|A0A1B7NXW9|A0A1B7NXW9_9EURO Uncharacterized protein OS=Emmonsia sp. CAC-2015a GN=ACJ72_04196 PE=3 SV=1 +----------------------NQSGKVLWLTNAaGG-LIVKEGIEifLDaeirhsGGEdATIRA------------------------- +>tr|A0A1I5X943|A0A1I5X943_9ACTN 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase OS=Actinomadura madurae GN=SAMN04489713_12623 PE=3 SV=1 +------KAAAYYDSYPALLDPGDVASAVRFALDQPPGVCCTEITITP-F-PV---------------------------- +>tr|A0A1Q9N1S0|A0A1Q9N1S0_9ARCH 3-oxoacyl-ACP reductase OS=Candidatus Lokiarchaeota archaeon CR_4 GN=RBG13Loki_0315 PE=3 SV=1 +----LTEEQIK---IMNPMDPEELVPFFLFFTTVEGKNVTGLVVDVELVKKVVN-------------------------- +>tr|A0A078HQR1|A0A078HQR1_BRANA BnaC04g14050D protein OS=Brassica napus GN=BnaC04g14050D PE=4 SV=1 +---GYKKSLFSRTPLGRAGEPKEVASLVAFCVYLQLHILLVRPFvLME--------------------------------- +>tr|B9S3E0|B9S3E0_RICCO Tropinone reductase, putative OS=Ricinus communis GN=RCOM_0732870 PE=3 SV=1 +---EVFRGCKSSNPNGKNRRTERGFC-IGSILMPTSSILHNRpdYLC----------------------------------- +>tr|A4XF84|A4XF84_NOVAD Short-chain dehydrogenase/reductase SDR OS=Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CIP 105152 / NBRC +--EEAEAAISATMALGRVPSDEECARGILVFLSDALSSVTGATLDINAGDYM---------------------------- +>tr|A0A059X0H4|A0A059X0H4_9BACT Short chain dehydrogenase OS=uncultured bacterium PE=4 SV=1 +---EAHARRSAELPLRGAADAEALADGVVAILN--LPSMTGQMLALDGGEHLEWPDR----------------------- +>tr|J3HKX0|J3HKX0_9RHIZ Uncharacterized protein OS=Phyllobacterium sp. YR531 GN=PMI41_04507 PE=3 SV=1 +---QDFNQQVSSLLLERGPDLSEFGRTIRYLWE--TRSITGQMIALDGGQHLAWETA----------------------- +>tr|A0A077FKQ9|A0A077FKQ9_9RICK 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Rickettsiales bacterium Ac37b GN=fabG_3 PE=4 SV=1 +---ENFTASRIHSPLNNAGSIEDIYNAIKFILT--TPSITGELINIDGGKHLSGELN----------------------- +>tr|A0A0P1FFS1|A0A0P1FFS1_9RHOB 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thalassobacter stenotrophicus GN=fabG_6 PE=4 SV=1 +-----AHASDQRFPGEGFANFSEVAAAVRYFSQ--APAVTGQLMSVRVE------------------------------- +>tr|A0A099T9T9|A0A099T9T9_9RHOB Short-chain dehydrogenase OS=Thalassobacter sp. 16PALIMAR09 GN=PM04_08855 PE=4 SV=1 +-----AHASDQRFTGEGFANFSEVATAVRYFSQ--APAVTGQLMSVRVE------------------------------- +>tr|F7XU01|F7XU01_MIDMI Short chain dehydrogenase OS=Midichloria mitochondrii (strain IricVA) GN=dltE PE=4 SV=1 +---ENFNKAIQYSLLKKNVSEKNLLDTIYYLIQ--NENLVGNIIFLEN-------------------------------- +>tr|A0A1F6QP30|A0A1F6QP30_9BACT Uncharacterized protein OS=Candidatus Melainabacteria bacterium RIFCSPLOWO2_12_FULL_35_11 GN=A3F80_02505 PE=3 SV=1 +---EYLKHSLDSVPLEKWGSIQNILQSIDFLCE--NDYLTGQCIFAGGGDHLR--------------------------- +>tr|A0A1Q9QA03|A0A1Q9QA03_RHOSU Short-chain dehydrogenase OS=Rhodovulum sulfidophilum GN=BV509_04695 PE=4 SV=1 +---APYAafRASTTPVTGRGSEpkglagCGDAAAALGYLLA--AKAVTGQVICVGDGHFSG--------------------------- +>tr|A0A1Q6DGI8|A0A1Q6DGI8_9CYAN Short-chain dehydrogenase OS=Limnothrix sp. CACIAM 69d GN=BJG00_01380 PE=4 SV=1 +---DYIQWRVQGIPVKQQGSTENISQAVSYILN--NPFVNGQILFVDGGESLTNVGQ----------------------- +>tr|A8P945|A8P945_COPC7 Short chain oxidoreductase OS=Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) GN=CC1G_09549 PE=4 SV=2 +--------KSNVAALGRMASPEDIAGIVSYLAGPDGKNVTGQTSLFIQILST---------------------------- +>tr|F3L577|F3L577_9GAMM Putative oxidoreductase OS=gamma proteobacterium IMCC3088 GN=IMCC3088_8 PE=4 SV=1 +---RFISNLSSQVPTKKVGRGLETAKLAAYLADPDVEHVVGQIIPLAGGWTT---------------------------- +>tr|A0A165USB9|A0A165USB9_9GAMM Short-chain dehydrogenase OS=Halioglobus sp. HI00S01 GN=A3709_00110 PE=4 SV=1 +---RFQERLKREVPLGRLVTAKEDVSLIAYLCSDVADCFVGQVFPMCGGWVG---------------------------- +>tr|A0A104JSN6|A0A104JSN6_BURGA Uncharacterized protein OS=Burkholderia gladioli GN=WJ59_11755 PE=3 SV=1 +LDAAIRERLIAEMPLRRMVSTDEIWLGLRFIIEC--DAFVGRTLAIDGGAS----------------------------- +>tr|A0A1H2KSI7|A0A1H2KSI7_9ACTN NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Gordonia westfalica GN=SAMN04488548_1343637 PE=4 SV +---SSRRLWPRRSRSRsasasptsTHNSPRSSPSTTT--------------------------------------------------- +>tr|S5ZGE2|S5ZGE2_9CREN Uncharacterized protein OS=Thermofilum adornatus GN=N186_09690 PE=3 SV=1 +--SPILQEYLRRIPIARLVEPEEIAKLAYHVVE--NEALTGIVIPIDLGTTIAS-------------------------- +>tr|A0A0K8LUG3|A0A0K8LUG3_PSESF 3-ketoacyl-(Acyl-carrier-protein) reductase OS=Pseudomonas syringae pv. actinidiae GN=fabG1 PE=3 SV=1 +------DELMKMIPAQRMGTPEEVAGAVNFLMSAEAATSPARCWPSMEGCADEACGG----------------------- +>tr|A0A103LL43|A0A103LL43_9BURK Short-chain dehydrogenase OS=Burkholderia sp. FL-7-2-10-S1-D7 GN=WS75_06560 PE=4 SV=1 +-------RAAGKTPLGRIAEPVELAEALFFLASEGARPLSGSAVSVDGGASVYGGSV-PCAAAEYDV------------- +>tr|A0A158LZC8|A0A158LZC8_9BORD Putative short chain dehydrogenase OS=Bordetella holmesii CDC-H585-BH GN=L497_2257 PE=4 SV=1 +-------RAVAKIPLGRLGDPQDLACALSFLASAEAAVLPADMLCVDGGSSIFGGSQ-AYLPTPHLP------------- +>tr|J4XP15|J4XP15_9FIRM KR domain protein OS=Selenomonas sp. FOBRC6 GN=HMPREF1148_1325 PE=4 SV=1 +--ARSIEMNAQGSAMRRNISLDETCAALEYLLADEASYLQGVNLNLSGGD------------------------------ +>tr|W3YZD9|W3YZD9_9FUSO Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Fusobacterium sp. CM21 GN=HMPREF1497_1198 PE=4 SV=1 +--ERLIEAEIEKHPLKRTIKIEEIVETINYILKSKNEFLNGNNILLTGGE------------------------------ +>tr|A0A1V5QC74|A0A1V5QC74_9FIRM Levodione reductase OS=Firmicutes bacterium ADurb.Bin354 GN=lvr PE=4 SV=1 +--PKVREMSLYKN--GKLLVPSDLFETMDEMLSEDFA-ENGTNRKICIS------------------------------- +>tr|B6HFH7|B6HFH7_PENRW Pc20g09760 protein OS=Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) GN=Pc20g09760 PE=4 SV=1 +---DWEQQLKYYGGFPRLAEVQELGGAYVYLLSEAASYTTSIDIPVNGVIGSKCFRV----------------------- +>tr|A0A1Y2EWR7|A0A1Y2EWR7_9BASI Uncharacterized protein OS=Leucosporidium creatinivorum GN=BCR35DRAFT_305997 PE=4 SV=1 +--ASQMENWGVGsvPLHGRVGQPAELGDSYVYLATNN--VTTGSVVHPNLGQHF---------------------------- +>tr|A0A1M7LAC2|A0A1M7LAC2_9BACT NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Chitinophaga jiangningensis GN=SAMN05444266_110220 +GHEKIQQYLDHLHPLGKMPEGDVIADTAVFLLSNAARFITGCIMPVSGGAELGYRT------------------------ +>tr|A9RGT3|A9RGT3_PHYPA Predicted protein OS=Physcomitrella patens subsp. patens GN=PHYPADRAFT_202254 PE=4 SV=1 +--EQIKERMAKKALLPnRPLTSLDVANAVLFLCSDEAGYISGHNLLLDAARTVGLPIpPGFSHWFEGYSPILK--------- +>tr|Q47PW1|Q47PW1_THEFY Short-chain dehydrogenase/reductase (SDR) family protein OS=Thermobifida fusca (strain YX) GN=Tfu_1472 PE=4 SV=1 +--AGAQEVL-GRTALLgRPIQPADVAAGILYLASDDAAFVTGAVLPVDAGLTGASWPspY-TSGRYAKPVALLE--------- +>tr|A0Z2D1|A0Z2D1_9GAMM Short-chain dehydrogenase/reductase (SDR) family protein OS=marine gamma proteobacterium HTCC2080 GN=MGP2080_11908 PE=4 SV=1 +--DEVEKTLAANSPLPgRAGTALDVANAALWLGSDESGYTSGLTLTTDAGVTTGSMVr---RPNYEDYVPMQR--------- +>tr|A0A1E4I4X5|A0A1E4I4X5_9PSEU Uncharacterized protein OS=Pseudonocardia sp. SCN 72-86 GN=ABS81_10920 PE=4 SV=1 +--DGARAAVLVETPLKdRVGLARDIAEAAVWLLSGAAGYVSGQTLIVDGGLVAGSPPasKGLSNAYSDRAPFLQ--------- +>tr|A0A1S4CTF9|A0A1S4CTF9_TOBAC secoisolariciresinol dehydrogenase-like OS=Nicotiana tabacum GN=LOC107822378 PE=4 SV=1 +---M-GKEGsDVYSTLNgAILTPNDVAETAVFLASDESKCVSGQDFVIDGGFTIENSGfs----LFK----------------- +>tr|A0A1U8LQ86|A0A1U8LQ86_GOSHI tropinone reductase-like 1 OS=Gossypium hirsutum GN=LOC107929762 PE=4 SV=1 +---SIVELKlSNMGNLKgEILKPECVAKAALYLASEEANYVSGVNLLVDGGYSAVNPTmf----KFANLVN------------- +>tr|A0A176VCY6|A0A176VCY6_MARPO Uncharacterized protein OS=Marchantia polymorpha subsp. ruderalis GN=AXG93_592s1000 PE=4 SV=1 +--QASSFFPKMKTSVShKIAGPDSIANAALFLASDDSAYVSGEDLAVDGSHMLQPGDpL--INAYKL---SVA--------- +>tr|A0A176W7E7|A0A176W7E7_MARPO Uncharacterized protein OS=Marchantia polymorpha subsp. ruderalis GN=AXG93_2490s1030 PE=4 SV=1 +--QTLSFFPAMKTGVShPIAGPDSIANAALFLASDDSSFVTGEDLVVDGSHMLCPEDlI--TKIIKS---ALK--------- +>tr|A0A0W1B3G2|A0A0W1B3G2_9BACL Uncharacterized protein OS=Paenibacillus etheri GN=UQ64_08230 PE=4 SV=1 +--DKSYDEYTNMNILGRVGHADEATHTTIYLMT--NKYTTGNTLFPDGGFILR--------------------------- +>tr|Q28S70|Q28S70_JANSC Twin-arginine translocation pathway signal OS=Jannaschia sp. (strain CCS1) GN=Jann_1525 PE=4 SV=1 +-NAAQDAMLNPALPLgeTPASEPQAIANTALYLASDLSADVSGAVLDTALGYNANYT------------------------- +>tr|A0A199AWV0|A0A199AWV0_9ACTN 3-ketoacyl-ACP reductase OS=Dietzia sp. 111N12-1 GN=AYO52_15845 PE=4 SV=1 +-LEDTAETFSGMNQMpQPWVEPSAIASMAVYLCSDEGAGITGASIPIDLGGSEKFG------------------------- +>tr|K0UWD8|K0UWD8_MYCVA Short-chain dehydrogenase OS=Mycobacterium vaccae ATCC 25954 GN=MVAC_06722 PE=3 SV=1 +-PDDLVQAARHYAILrgNKGIESEQVSKTVAFLLSKEASILTGVIMPVDAGHSIMNR------------------------- +>tr|A0A1R4G908|A0A1R4G908_9MICO Short-chain dehydrogenase/reductase SDR OS=Frigoribacterium sp. JB110 GN=CZ774_13060 PE=4 SV=1 +-AEDAEAAFAGLNPFgKAWIEPIHVSNAVAWLASDQSYYVSGGQIPVDGAAAVQ--------------------------- +>tr|A0A137SK63|A0A137SK63_9GAMM 3-oxoacyl-[acyl-carrier protein] reductase OS=Moritella sp. JT01 GN=AKG98_4025 PE=4 SV=1 +--EKLMENEVSNIPLQKYASVDDVTGAILALMGPLSNHMTGQNILLDGGFNKCY-------------------------- +>tr|A0A1M3CL17|A0A1M3CL17_9RHIZ Uncharacterized protein (Fragment) OS=Shinella sp. 65-6 GN=BGO06_21980 PE=3 SV=1 +------LNPVSKIPKDKLV-PAvVPASCMAWLCGPGSDGLEEVLLDVRQDLFTRQ-------------------------- +>tr|B4UA19|B4UA19_HYDS0 Dehydrogenase OS=Hydrogenobaculum sp. (strain Y04AAS1) GN=HY04AAS1_1295 PE=4 SV=1 +MEDEEWQKVITNTPLKKEVSLHDIYSVLKLFLE--TTSITGAILPIDGGRHIK--------------------------- +>tr|A0A0B1TEG3|A0A0B1TEG3_OESDE Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Oesophagostomum dentatum GN=OESDEN_06307 PE=4 SV=1 +--EAKLVEEHSYIPYQCIGKPEEIAEAILFLADRKrSNYIVGHQLVIDGGASLQMPVI----------------------- +>tr|E3NW63|E3NW63_CAERE Putative uncharacterized protein OS=Caenorhabditis remanei GN=CRE_28011 PE=4 SV=1 +--YNTMGSLPHCIPVGFCAQPEHIASVIAFLADRKaSEYIVGQTITADGGSTLVLGFH----------------------- +>tr|A0A0F7SLP9|A0A0F7SLP9_PHARH Reductases with broad range of substrate specificities OS=Phaffia rhodozyma PE=4 SV=1 +--KTWVDEWVYRTPLGRMATAQDIGKSVVAMCSDNFMFMTGSDVLVDGGYACL--------------------------- +>tr|A0A0R1LKR7|A0A0R1LKR7_9LACO Uncharacterized protein OS=Lactobacillus acidifarinae DSM 19394 GN=FD25_GL002634 PE=4 SV=1 +--PKVSASFHDFHPLNRNGQLADIAQAILFLASERASWITGQRWGHISSALT---------------------------- +>tr|A0A0S7HS73|A0A0S7HS73_9TELE DHB14 OS=Poeciliopsis prolifica GN=DHB14 PE=4 SV=1 +-AAAAVQAGENAQLMGRMGTEAECGLAALFLAA-DATFCTGIDLLLSGGAELNYGF------------------------ +>tr|Q93P93|Q93P93_9BACT MS138, putative dehydrogenase OS=Microscilla sp. PRE1 PE=4 SV=1 +-GEKIIRSIkERVPFENRMTRTDEIANAALFLISEKSSHTTGQHVFVDGGYIHLDRA------------------------ +>tr|A0A1I8H4X7|A0A1I8H4X7_9PLAT Uncharacterized protein OS=Macrostomum lignano PE=4 SV=1 +-EGgggdtteDQLARYASDSLFNRLGSIEEIGAACLFLCR-WATYCTGIELPVTAGVELAKPM------------------------ +>sp|O67505|FABI_AQUAE Enoyl-[acyl-carrier-protein] reductase [NADH] FabI OS=Aquifex aeolicus (strain VF5) GN=fabI PE=1 SV=2 +--HLLMEHTTKVNPFGKPITIEDVGDTAVFLCSDWARAITGEVVHVDNGYHI---------------------------- +>tr|A0A0K8MA34|A0A0K8MA34_PSESF Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Pseudomonas syringae pv. actinidiae GN=PSA5_31545 PE=3 SV=1 +--SGLSDTYAKKLQPTGTPSVNEILNVAIFLISDNSIGVTGDRIFVDGGFHN---------------------------- +>tr|V4L1S7|V4L1S7_9DELT Enoyl-[acyl-carrier-protein] reductase [NADH] OS=uncultured Desulfofustis sp. PB-SRB1 GN=N839_03135 PE=3 SV=1 +--SNLLKVASDASPLGHTAELEDIGTMAVEVITN--PSINGVVYLVDCGASA---------------------------- +>tr|A0A0W0RBZ4|A0A0W0RBZ4_9GAMM Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Legionella anisa GN=fabI_3 PE=3 SV=1 +--DNLMEKAANEAPLHQLVTIEAIGETVAFWCRIKPLPLRDKFSMWMAAI-T---------------------------- +>tr|A0A1C7HDZ8|A0A1C7HDZ8_9BURK Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Burkholderiales bacterium YL45 GN=A4V04_04825 PE=3 SV=1 +--GLLMKLAKDLSLLRSLVSTEEVGNLAAFLLSEKSFGITAETVYIDGGFNK---------------------------- +>tr|C4FIX8|C4FIX8_9AQUI Short-chain dehydrogenase/reductase SDR OS=Sulfurihydrogenibium yellowstonense SS-5 GN=SULYE_0518 PE=3 SV=1 +--DIE--KPLQKTLIKKWAGGKEVFKAVKYLI-E-TDFTTGALIPVEGGRLI---------------------------- +>tr|A0A1F9UD83|A0A1F9UD83_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_60_11 GN=A3A86_01395 PE=4 SV=1 +--QKEWDAYrlrsRVKFPVSDKEAVEQFALLALYLC-T-VTLTSGNTYPLDQGHNL---------------------------- +>tr|A0A1D9FUB0|A0A1D9FUB0_9CYAN Glucose dehydrogenase OS=Moorea producens JHB GN=BJP36_02350 PE=3 SV=1 +-PQAFMENYaRKFIPLKIPGNTKVVTDSALFLL-E-QDFLTGSTITLDGGQYI---------------------------- +>tr|U5W1L1|U5W1L1_9ACTN Uncharacterized protein OS=Actinoplanes friuliensis DSM 7358 GN=AFR_17935 PE=4 SV=1 +--ERLFASAG-------AVDAEDVAKAYLGFLD--QDHATGNVAVVEGRSAG---------------------------- +>tr|A0A1C4BSE1|A0A1C4BSE1_9BACT NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Chitinophaga costaii GN=GA0116948_103237 PE=4 SV=1 +--QQSFAYFSSLVHAGRVGRAEEVAAAIYAVLS--NDYINAAIIPVTGGVS----------------------------- +>tr|A0A1C4BB22|A0A1C4BB22_9BACT NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Chitinophaga costaii GN=GA0116948_10317 PE=4 SV=1 +--KSFLSNHAANLAVGRIGQAIDVAEVIELVTR--CGFITGSIYQVNGGSHLTT-------------------------- +>tr|A0A015WJZ2|A0A015WJZ2_BACFG Short chain dehydrogenase family protein OS=Bacteroides fragilis str. J-143-4 GN=M067_1644 PE=4 SV=1 +-PEEIKQNIYKKTAIHRFATIDEIVDAFRFCID--NPFINGSLIEVNGGYNF---------------------------- +>tr|A0A1T4KRM6|A0A1T4KRM6_PORCN 3-oxoacyl-[acyl-carrier protein] reductase OS=Porphyromonas cangingivalis GN=SAMN02745205_00847 PE=4 SV=1 +-PTDVRKSIEGKVASHRFASPEEVGQVFKMVAE--NEYFNGDIISLSGGYSY---------------------------- +>tr|N8R639|N8R639_9GAMM Uncharacterized protein OS=Acinetobacter sp. CIP-A165 GN=F991_02610 PE=4 SV=1 +VPQERHDLYVNGRAIQRQQLPQDLNGTALYLLSELSSFVTGQNIPVNGGFVFN--------------------------- +>tr|Q6SGK1|Q6SGK1_9BACT Oxidoreductase, short chain dehydrogenase/reductase family OS=uncultured marine bacterium 560 GN=MBMO_EBAC750-16D01.3 PE=4 SV=1 +VSATRHSFYNENRAVPGPQAPEDITETISFLLTKGALTLTGQLLTVNNGFVFS--------------------------- +>tr|C8WQD2|C8WQD2_ALIAD Short-chain dehydrogenase/reductase SDR OS=Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / +----------RTEEGLRPPVGEDVARAVEWFLREDSQEVNGTVLEVTGAREIVAKDS-FPRRPE---------------- +>tr|U1PML0|U1PML0_9EURY Dehydrogenase OS=halophilic archaeon J07HB67 GN=J07HB67_00366 PE=3 SV=1 +----------DTHLPQYACEPETVAHTVEYLLENDYVXXXXXXXvvahtavSFRGPQGRFHSRG-R--------------------- +>tr|A0A1F8JIX3|A0A1F8JIX3_9PROT Enoyl-ACP reductase (Fragment) OS=Caulobacterales bacterium RIFOXYA1_FULL_67_7 GN=A3K57_12950 PE=4 SV=1 +--RGMISQGRAMSAMKEDTSMEGVAGAALWLCSDLGLSTTGEVVHVDAGFHM---------------------------- +>tr|A0A1J8YU79|A0A1J8YU79_9BURK Enoyl-ACP reductase (Fragment) OS=Burkholderia ubonensis GN=BGV55_24425 PE=4 SV=1 +--DLLLNEAVERAPLGELVDIMDVGFSCAYLATPYARRITGNTMFIDGGVSI---------------------------- +>tr|A0A139AD21|A0A139AD21_GONPR NAD(P)-binding protein OS=Gonapodya prolifera JEL478 GN=M427DRAFT_33166 PE=4 SV=1 +YTSPFINEIAKIKPNRRAELLEDEAQGIVIMCMPGMSAMHGHFTMVDGGVNL---------------------------- +>tr|A0A1F8PRJ9|A0A1F8PRJ9_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_51_16 GN=A2Y54_06255 PE=4 SV=1 +--SMSS-EYVARRIVDLAKRPRRSLVIPFWflplvtinnIFPGMVDWILGNFFinryhKLDAGAS----------------------------- +>tr|A0A1J6XEU1|A0A1J6XEU1_9MICO Uncharacterized protein OS=Microbacterium sp. AR7-10 GN=BFN01_05580 PE=3 SV=1 +--ADVRAEMVSGTATRSTVSPDDVLASVEYLLDPRNRNITGQDINVSAGAV----------------------------- +>tr|A0A1N7G7V9|A0A1N7G7V9_9EURY 3-oxoacyl-[acyl-carrier protein] reductase OS=Natronorubrum thiooxidans GN=SAMN05421752_11086 PE=3 SV=1 +-------AHLPASEREEILQPDVMNDAAVLLAAQGSDGVTGESMAAQEWEQ----------------------------- +>tr|A0A1M6BIS8|A0A1M6BIS8_9FLAO NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Arenitalea lutea GN=SAMN05216261_0751 PE=4 SV=1 +-EEELKREAAEALPMGRMLNRFDPVPAVMHFISDDSAMTTGSLMRITGGEYI---------------------------- +>tr|A0A0L9ST48|A0A0L9ST48_9HYPO Uncharacterized protein OS=Ophiocordyceps unilateralis GN=XA68_2342 PE=4 SV=1 +RPAGQMEGFGQKSQLGRPGQPSEVAPSYVFLASKDSELFYGQKLFLLGTSSDLHPTT--LVPR----------------- +>tr|R8BTI6|R8BTI6_TOGMI Putative versicolorin reductase protein OS=Togninia minima (strain UCR-PA7) GN=UCRPA7_1775 PE=4 SV=1 +-PMEIIDAGLaKMCPLKRVGTPADIGKAVFTLCSEEGEWINGTSLFSSFSNKI---------------------------- +>tr|A0A1J4RRY9|A0A1J4RRY9_9BACT Uncharacterized protein OS=Candidatus Berkelbacteria bacterium CG1_02_42_45 GN=AUJ40_00475 PE=4 SV=1 +--SGFIKAVAEHAPQGEVTTE-NIADAIVGLVSGMAMHMGGGVFSIDHGHFS---------------------------- +>tr|A0A1E7FW84|A0A1E7FW84_9STRA NAD(P)-binding protein OS=Fragilariopsis cylindrus CCMP1102 GN=FRACYDRAFT_232542 PE=4 SV=1 +--ERMRQDVQIRAPLGNVTSSQVAATVYHVA--AEACGMTGQTIEVDGGYSI---------------------------- +>tr|A0A1F3SY98|A0A1F3SY98_9PROT Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Bdellovibrionales bacterium GWB1_55_8 GN=A2X94_05850 PE=3 SV=1 +--RTMLAAAEEKTPLRENISAEDVGEMGAFLCGPGGLHVTGSTLYLDSGAHI---------------------------- +>tr|A0A179FGQ0|A0A179FGQ0_METCM Gluconate 5-dehydrogenase OS=Pochonia chlamydosporia 170 GN=VFPPC_05704 PE=3 SV=1 +-NPEGLDAIEERvmsatAAGHRIAETRDIAPIVAFLCEEQSRWITGSVTCANGGYVTV--------------------------- +>tr|A0A0F9X631|A0A0F9X631_TRIHA Glucose and ribitol dehydrogenase OS=Trichoderma harzianum GN=THAR02_07862 PE=3 SV=1 +-TTESVKEIS--egTFFRRPAQPAELAPLYVSVVDASSS-VPGDPFLLWF-------------------------------- +>tr|R7C8H5|R7C8H5_9CLOT Uncharacterized protein OS=Clostridium sp. CAG:62 GN=BN737_00737 PE=4 SV=1 +---QLKEVEK-RQYLG-VSDAADIAKTICFLLGEEAKAITGTSMDVSGGFLTS--------------------------- +>tr|A0A0P5JGN2|A0A0P5JGN2_9CRUS Dehydrogenase/reductase sdr family member OS=Daphnia magna PE=4 SV=1 +------TLMYHNCPMRRNGKPEEMAGFAAFFSWHRMTRRTLPEatLLLLeecNPI------------------------------ +>tr|A0A0K0EK38|A0A0K0EK38_STRER Uncharacterized protein OS=Strongyloides stercoralis PE=4 SV=1 +-DEV-RGQLEQVIPLGRVAKVYECTSTVEFLCGRGAMFTNGENFVINGGVSVR--------------------------- +>tr|Q3SHP7|Q3SHP7_THIDA Possible oxo-acyl acyl carrier protein dehydrogenase OS=Thiobacillus denitrificans (strain ATCC 25259) GN=Tbd_1886 PE=4 SV=1 +LTAEQIGELASATQFGRLPQLGDVSRLAMFLCSEENTGITGQFIAADLGFS----------------------------- +>tr|A0A094PBW4|A0A094PBW4_9ACTN Uncharacterized protein OS=actinobacterium acIB-AMD-7 GN=GM48_4400 PE=4 SV=1 +LKPEQIENVQGQTPGKKMVTPSDVANATYLLGCEDNTAISGQSLFVDYGFA----------------------------- +>tr|A0A0R2QP35|A0A0R2QP35_9ACTN Dehydrogenase OS=Actinobacteria bacterium BACL4 MAG-121001-bin59 GN=ABR73_03200 PE=4 SV=1 +LKPEQIENVQWQTPGHKMVIPSDVASATYLLGCEENTAISGQSLFVDYGFS----------------------------- +>tr|A0LSD4|A0LSD4_ACIC1 Short-chain dehydrogenase/reductase SDR OS=Acidothermus cellulolyticus (strain ATCC 43068 / 11B) GN=Acel_0571 PE=4 SV=1 +-DASTMAFIARKQALtGGILAARHVTELAVELCSARTTALTGQLIAVDGGWSVL--------------------------- +>tr|A0A1F9ZPE3|A0A1F9ZPE3_9FIRM Uncharacterized protein OS=Firmicutes bacterium GWF2_51_9 GN=A2Y20_07615 PE=4 SV=1 +-DEDILNYMDYKQPIyASKHklgNPLSVAKAATFLAAKESDFITGIILPVDGGWTAQ--------------------------- +>tr|A0A0S4P922|A0A0S4P922_9BURK Short-chain dehydrogenase/reductase SDR OS=Janthinobacterium sp. CG23_2 GN=BN2497_12435 PE=4 SV=1 +LDPKLRESYRRYSALGRTGTCAEAARGLRWLALENT-YLNGAQFPLTGGL------------------------------ +>tr|A0A1F8XCZ5|A0A1F8XCZ5_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium GWA2_65_63 GN=A2X90_11270 PE=4 SV=1 +-FPEERWERLRakKRRGRGIGTPEGVARAVLRFARARQ-YNS---------------------------------------- +>tr|K0NFV3|K0NFV3_DESTT FabG: short-chain dehydrogenase/reductase family protein OS=Desulfobacula toluolica (strain DSM 7467 / Tol2) GN=fabG PE=4 SV=1 +LTTDEKQSLIDHILLNRTGCVEDVVKACLFIVKD-APYMTGSILRLDGGYVLA--------------------------- +>tr|S3CS81|S3CS81_GLAL2 NAD(P)-binding Rossmann-fold containing protein OS=Glarea lozoyensis (strain ATCC 20868 / MF5171) GN=GLAREA_09661 PE=4 SV=1 +-PQSKIDNNIANSVLKRLASVEDVANMILCISNS--SSQTGTNTVIEAGRTL---------------------------- +>tr|A0A127EPU8|A0A127EPU8_9RHIZ Short-chain dehydrogenase/reductase SDR OS=Rhodoplanes sp. Z2-YC6860 GN=RHPLAN_08260 PE=4 SV=1 +-GREGVEKQAATTPLKIVAEADDVALAIIAGITHL-RLTTGSTIVVDSGRHL---------------------------- +>tr|A0A072P9X7|A0A072P9X7_9EURO Alcohol dehydrogenase OS=Exophiala aquamarina CBS 119918 GN=A1O9_11580 PE=4 SV=1 +-SAERLQIAQQKSSLKRFATVEACIHCVQAVAEN--KSMTGINSVLDAGFLL---------------------------- +>tr|L7IGN4|L7IGN4_MAGOY Uncharacterized protein OS=Magnaporthe oryzae (strain Y34) GN=OOU_Y34scaffold00215g14 PE=4 SV=1 +----VQESNIARSKLKRVVTPEVRIKPPTWAPLS---------------------------------------------- +>tr|A0A0J0XH69|A0A0J0XH69_9TREE Putative short-chain dehydrogenase OS=Cutaneotrichosporon oleaginosus GN=CC85DRAFT_287485 PE=4 SV=1 +-SEAQVKMSTDAALLKKVSDVPDVAAAYIMLMEN--GSITGEILEISAGLGH---------------------------- +>tr|A0A1K1Y2T4|A0A1K1Y2T4_9ACTN NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Olsenella sp. kh2p3 GN=SAMN04487823_10975 PE=4 SV=1 +-------------AAGRLATSLEMAWPIVFVNSAGASFVSGLELNVDYADTQMKALK----------------------- +>tr|M5AW56|M5AW56_PSEPU Putative short-chain dehydrogenase/reductase SDR OS=Pseudomonas putida PE=3 SV=1 +--ASHDAATKADIPLGgKFGDVDkDLAPVMVFLASDASHFISRPDVPGRRWAYCGAM------------------------- +>tr|A0A0G4NY39|A0A0G4NY39_PENCA Short-chain dehydrogenase/reductase SDR OS=Penicillium camemberti FM 013 GN=PCAMFM013_S002g000764 PE=3 SV=1 +--AGHDVFMNDRICLGeKFGDVEiDLVPVLAFLVSDASCWITGQLVPVNGGLSLTLV------------------------- +>tr|A0A193FHB9|A0A193FHB9_9BORD Uncharacterized protein OS=Bordetella bronchialis GN=BAU06_10380 PE=4 SV=1 +-PPGHIEANRHAIPMGREATAREVAQVIVFLASRLSTFMTGTEVAVDGGLSTSGVAW-----MRRAFQQALAGPVPDVRR +>tr|A0A178J534|A0A178J534_9VIBR Uncharacterized protein OS=Vibrio europaeus GN=AZ468_24475 PE=4 SV=1 +----FIDTIESAIPLNeI-CGQHDIVHGVRFLASDSNTALTGQNININGGWLM---------------------------- +>tr|A0A1Y1INL0|A0A1Y1INL0_KLEFL 3-ketoacyl-ACP reductase OS=Klebsormidium flaccidum GN=KFL_009580010 PE=3 SV=1 +--ESAK-LVQRAVPARrYGDTETDLMGALLLLVSeKASRYIVGVTIPVDGGHSLYT-------------------------- +>tr|A0A1I5QYS3|A0A1I5QYS3_9PSED Uncharacterized protein OS=Pseudomonas composti GN=SAMN05216601_113123 PE=4 SV=1 +-NTQLNALVAGNTALDRTSLTISE-------RGEGGRWVNGQRIEASGCMFL---------------------------- +>tr|A0A077REA8|A0A077REA8_9BASI Conserved hypothetcial protein OS=Melanopsichium pennsylvanicum 4 PE=4 SV=1 +--KQVLQSRGDKLLTGRVGQPEDLANVYIYLTK--DKNITAQIIVSDGGDS----------------------------- +>tr|A0A0L8IN25|A0A0L8IN25_PSESX Short chain dehydrogenase OS=Pseudomonas syringae pv. aceris GN=ALO91_102840 PE=4 SV=1 +---EGYLRMIELSPAGRGGTPDEVGALAALLMGPEGTFITGSDFLMDGGVTASYWYG-DLAPA----------------- +>tr|B7CA69|B7CA69_9FIRM Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Holdemanella biformis DSM 3989 GN=EUBIFOR_01090 PE=3 SV=1 +------DLSLDYSPSKRYAAPEEIANLATVLVSGMGRMIVGDTIYATGGAGILT-------------------------- +>tr|R7K386|R7K386_9CLOT Oxidoreductase short chain dehydrogenase/reductase family protein OS=Clostridium sp. CAG:277 GN=BN584_00918 PE=3 SV=1 +------TLYTDCIPAKRFATPSEIGQLAVIMVSDMCNLVVGDTFYISGGSGTTK-------------------------- +>tr|S0KBP1|S0KBP1_ENTAV Uncharacterized protein OS=Enterococcus avium ATCC 14025 GN=OMU_03227 PE=3 SV=1 +------SIESFENPTGRLVTPVEIGEWAVYMVSAIGQYAVGTVMHLTGGNGIFQ-------------------------- +>tr|A0A0J8YZB5|A0A0J8YZB5_9FIRM 3-oxoacyl-[acyl-carrier-protein] reductase OS=Coprobacillus sp. 8_1_38FAA GN=HMPREF0979_01847 PE=3 SV=1 +------DISCNAQPNKRYIDPIEKSQIATMLVSGIGNSIVGDSIYVSGGNGTFY-------------------------- +>tr|A0A1G9INT1|A0A1G9INT1_STREI 3-oxoacyl-[acyl-carrier protein] reductase OS=Streptococcus equinus GN=SAMN05216400_0265 PE=4 SV=1 +------NLWR-DCSSGRVFLPEEVAEVACFLLSGASKCISGEVIHCNAANHRKV-------------------------- +>tr|V7F7U3|V7F7U3_9RHIZ Short-chain dehydrogenase OS=Mesorhizobium sp. LSHC420B00 GN=X759_35305 PE=4 SV=1 +LDECMQRHLRRHQLLPRVGRPEDVAALVAFLLSDDAAFITGQVVCIDGGMLTHVPTYADGGNSRAARPSGDTAEADAAPR +>tr|A0A024IYV0|A0A024IYV0_RHIRD Short-chain dehydrogenase/reductase SDR OS=Rhizobium radiobacter GN=BN949_03342 PE=4 SV=1 +--EPAYEYWGKLCLVQRPATVEEQAHAALFLLD--NTNMTGNTLFSDGGYSLR--------------------------- +>tr|V5HE32|V5HE32_IXORI Putative mitochondrial/plastidial beta-ketoacyl-acp reductase OS=Ixodes ricinus PE=2 SV=1 +TPEKVRKGIIEEIPMKRIATPLEMSEVIVFMCGPRSTYMVGADRPGVRRDVS---------------------------- +>tr|R6XYA7|R6XYA7_9CLOT Putative 3-oxoacyl-[acyl-carrier-protein] reductase OS=Clostridium sp. CAG:433 GN=BN654_00547 PE=3 SV=1 +MNPEFLDSELKRIGQEKLFTVEDVSKQIINIIKDEQ-IKSGMIIELED-------------------------------- +>tr|R7M1Y9|R7M1Y9_9CLOT Putative 3-oxoacyl-[acyl-carrier-protein] reductase OS=Clostridium sp. CAG:914 GN=BN809_00189 PE=4 SV=1 +IDKTFLDNELKRIGQTRLIEVNELINTISEIIN---NFESGSCYRIDI-------------------------------- +>tr|R6B0M5|R6B0M5_9CLOT Uncharacterized protein OS=Clostridium sp. CAG:533 GN=BN698_00783 PE=3 SV=1 +MDEEY------KKSLGVFLKPEEVAKVVYDISVDE--GVSDAVIRVGD-------------------------------- +>tr|A0A1B8HGR3|A0A1B8HGR3_9GAMM Uncharacterized protein OS=Morganella psychrotolerans GN=AYY16_02360 PE=4 SV=1 +-SGLNKDLINLVSPADKVGTVKDIIDSIRFLLT--SDYINGTIMPVDGGYSAGNW------------------------- +>tr|A0A085G814|A0A085G814_9GAMM 3-oxoacyl-[acyl-carrier protein] reductase OS=Ewingella americana ATCC 33852 GN=GEAM_2642 PE=4 SV=1 +-SGGDGVFLRALSPAGRTGSTQDIVDAVFYLVD--ARFTSGVVLPIDGGATAGVW------------------------- +>tr|A0A0B3AUA3|A0A0B3AUA3_9ARCH Clavaldehyde dehydrogenase OS=archaeon GW2011_AR17 GN=QT08_C0012G0023 PE=3 SV=1 +--------------KWKMLRSEDIAEYIIALASRDILRIV-yVRILNVWRRFY---------------------------- +>tr|A5UTC3|A5UTC3_ROSS1 Short-chain dehydrogenase/reductase SDR OS=Roseiflexus sp. (strain RS-1) GN=RoseRS_1481 PE=3 SV=1 +----------GEEFRRRLMTAADVAEVILWVCTLPPTVRVDELPIMPRQIDM---------------------------- +>tr|A0A1G3BNZ2|A0A1G3BNZ2_9BACT Uncharacterized protein OS=Planctomycetes bacterium RIFCSPLOWO2_02_FULL_50_16 GN=A3I59_07175 PE=4 SV=1 +----------PEHEPEGLLTPEEVAQKILSLSDPDDGTRSGTSVHIHKRY------------------------------ +>tr|A0A1J4RR02|A0A1J4RR02_9CHLR Uncharacterized protein OS=Anaerolineae bacterium CG1_02_58_13 GN=AUJ21_11140 PE=4 SV=1 +----------ALRRYFHSMTSEEVAERVIELAKRPRRAVILpwYYKIAIWADWY---------------------------- +>tr|A0A1F9PEU7|A0A1F9PEU7_9DELT Uncharacterized protein OS=Desulfobacterales bacterium RIFOXYA12_FULL_46_15 GN=A2277_08525 PE=4 SV=1 +----------APLLDEEMIQPEDIMKTIAWVLELAPNTCVREITLECFKSIA---------------------------- +>tr|A0A1G3R3L1|A0A1G3R3L1_9SPIR Uncharacterized protein OS=Spirochaetes bacterium RBG_16_67_19 GN=A2V99_02175 PE=4 SV=1 +----------SLDPKTRLLEPEDLALMVQYLIETPGHFSIWNMDLVALEQSF---------------------------- +>tr|A0A1F8TG15|A0A1F8TG15_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_19FT_COMBO_62_14 GN=A2Z37_10775 PE=3 SV=1 +----------WRTPVSMVLSPEHVAESIIGLTRRPRATLVLppYYRLVIWLDFI---------------------------- +>tr|A0A238VH60|A0A238VH60_9BACT NADP-dependent 3-hydroxy acid dehydrogenase YdfG OS=Hymenobacter mucosus GN=SAMN06269173_101645 PE=4 SV=1 +----------GQEPDPHKMQPEDIAAAIVHALEAPQTVMISELQMRPTQPK----------------------------- +>tr|A0A1E4ZLS9|A0A1E4ZLS9_9BACT Uncharacterized protein OS=PVC group bacterium (ex Bugula neritina AB1) GN=AB834_03890 PE=3 SV=1 +LTKDSVEKYRLENTLKDLASMESICQSVYDIS--FWPQVSGQTFVLDSR------------------------------- +>tr|A0A1F6RNL5|A0A1F6RNL5_9BACT Uncharacterized protein OS=Candidatus Moranbacteria bacterium RIFCSPHIGHO2_01_FULL_55_24 GN=A2808_02535 PE=4 SV=1 +VDKDVQEDILHPKDIADLTLH---------LSGTPSRVI------FDEI------------------------------- +>tr|K2E6A9|K2E6A9_9ZZZZ 3-ketoacyl-(Acyl-carrier-protein) reductase OS=groundwater metagenome GN=fabG PE=4 SV=1 +NDDKLWKGFADHNPMKRVATVEDVADAVIPLINDPHKFLNGNFLFVNGGNHL---------------------------- +>tr|A0A1A2SLN5|A0A1A2SLN5_9MYCO Short-chain dehydrogenase OS=Mycobacterium colombiense GN=A5685_19820 PE=4 SV=1 +IYTHLasNPDWNMRVALGRGGCPVEAGELIAFLLGERAAFMTGAAINIDGGTDF---------------------------- +>tr|R0G198|R0G198_9BURK Short-chain dehydrogenase/reductase SDR OS=Herbaspirillum frisingense GSF30 GN=HFRIS_021031 PE=4 SV=1 +--AGLKEKVAAAFPARRVGRAEDIGHAALFLMT--NPYVTGTVVEVSGGETLVDS------------------------- +>tr|C9LJR4|C9LJR4_9BACT Uncharacterized protein OS=Alloprevotella tannerae ATCC 51259 GN=GCWU000325_02478 PE=4 SV=1 +FPQELKKVFSKNSPLERIVEPDEIAKAVFFMATDASSAITGETIPVTAGFEISTGQ------------------------ +>tr|A0A0B7KEH3|A0A0B7KEH3_BIOOC Uncharacterized protein OS=Bionectria ochroleuca GN=BN869_000012036_1 PE=4 SV=1 +FTNTELELAS-qv-LEFHRLAQPAEVAMHYVEVADPANTYMSGEVIAIAGA------------------------------- +>tr|A0A0C9S1T7|A0A0C9S1T7_9SPER TSA: Wollemia nobilis Ref_Wollemi_Transcript_22637_1458 transcribed RNA sequence OS=Wollemia nobilis PE=4 SV=1 +--DKVEQSVKDIVPLQRWLDTKnDLSAIVLYLVSDDSSFMTGTVIFVDGGQSIVRPR------------------------ +>tr|A0A0U1LXV9|A0A0U1LXV9_9EURO Carbonyl reductase, putative OS=Talaromyces islandicus GN=PISL3812_04944 PE=4 SV=1 +VPQETKDIWKDKIPLGFVSLPPLKPFsnkltsedgRVRVTNSKVHSYIsllTQQAIQLGQTY------------------------------ +>tr|W6WR65|W6WR65_9BURK 3-oxoacyl-(Acyl-carrier-protein) reductase OS=Burkholderia sp. BT03 GN=PMI06_005612 PE=3 SV=1 +---ETHKALGSLHPVGHMGEMSDIVNAVLYLDS--ASSPAvtvrSPVLHSLDLARRGRVAH----------------------- +>tr|A0A069PLA1|A0A069PLA1_9BURK 3-oxoacyl-ACP reductase OS=Caballeronia glathei GN=BG61_23560 PE=4 SV=1 +---------HRAASEGTRETIREIVDAVLDLTD--TDSMTGKVIPVGGLLADAA-------------------------- +>tr|A0A1X1Y2A4|A0A1X1Y2A4_9MYCO 3-oxoacyl-ACP reductase OS=Mycobacterium kubicae GN=AWC13_26435 PE=4 SV=1 +---VDaCAAYARMHPQNRIGGVADVVHGALYLEM--SPFVTGEILHIDGGQSAGHTNP----------------------- +>tr|K0S486|K0S486_THAOC Uncharacterized protein OS=Thalassiosira oceanica GN=THAOC_24515 PE=4 SV=1 +-DPNVVDMWTPHLPVGRLGKVDDIADATLMLAT--NEWMSGSIVTVDGGMTGRANMPFRPRPARQSAPEV---------- +>tr|B7G461|B7G461_PHATC Predicted protein OS=Phaeodactylum tricornutum (strain CCAP 1055/1) GN=PHATRDRAFT_47583 PE=4 SV=1 +-DPSNVQAWADRIPLGKLGTVEHVAQACLPLLT--NDWITGAIWQVDGGMMARSNMPTRPRPLKFGGIC----------- +>tr|A0A0G0Z911|A0A0G0Z911_9BACT Uncharacterized protein OS=Parcubacteria group bacterium GW2011_GWA2_42_18 GN=UV08_C0007G0017 PE=4 SV=1 +ISEAEKKMCESRTMINRYVADDEIALAAIGILE--NDAITGQIITVDGGLSLQKLER----------------------- +>tr|A0A0G0TQ71|A0A0G0TQ71_9BACT 3-oxoacyl-ACP reductase OS=Candidatus Levybacteria bacterium GW2011_GWA2_40_8 GN=UU21_C0001G0025 PE=4 SV=1 +PDKKGQEELGQVHLIKRMIQPDEIAECIVFLAK--SDVICGEVFTVDGGMSLVTLG------------------------ +>tr|A0A1Q3P4J3|A0A1Q3P4J3_9PROT Uncharacterized protein OS=Alphaproteobacteria bacterium 33-17 GN=BGO27_07210 PE=4 SV=1 +PDNFMFRA--TDNVLGNIIDVAQVISTIDFLIN--NKAITGEIIRVDSGKHLQMKSD----------------------- +>tr|N1Q1E2|N1Q1E2_DOTSN Uncharacterized protein OS=Dothistroma septosporum (strain NZE10 / CBS 128990) GN=DOTSEDRAFT_40319 PE=4 SV=1 +-DNKVVERALATVPLQKVALPEDVARQVAVMASPsLSGHVNGVNLQVGQYL------------------------------ +>tr|A0A0C9U8K4|A0A0C9U8K4_9HOMO Unplaced genomic scaffold SPHSTscaffold_344, whole genome shotgun sequence OS=Sphaerobolus stellatus SS14 GN=M422DRAFT_193561 P +-HALILILFlRNRTPLKKFARPEHVTHQIVILASPiLSGHISREVVVVAGGM------------------------------ +>tr|E4PIC6|E4PIC6_MARAH Short-chain dehydrogenase/reductase SDR OS=Marinobacter adhaerens (strain HP15) GN=HP15_67 PE=4 SV=1 +-SEEYKEKSLNKSVLGIEPGPEVVYQGVRYLMD--NIYVTGECLNLDGGRHL---------------------------- +>tr|K0Q512|K0Q512_9RHIZ Putative short-chain type dehydrogenase/reductase OS=Rhizobium mesoamericanum STM3625 GN=BN77_p270036 PE=4 SV=1 +LDERLQRQLHRHQLLAHVGRPEDVAALVVFLLSDDAAFITGQVVCIDGGMLAHLPTYADGGNNPAERPVD---------- +>tr|W3X0E3|W3X0E3_9PEZI Uncharacterized protein OS=Pestalotiopsis fici W106-1 GN=PFICI_08680 PE=4 SV=1 +--RDIPDWHQNGAPFQRLGLPKDLTPMVCYLLSDASASTTGADMLITELQLDYT-------------------------- +>tr|A0A0D3RJC1|A0A0D3RJC1_STRAD Ketoacyl-(Acyl-carrier-protein) reductase OS=Streptomyces alboniger GN=pamM PE=4 SV=1 +-NPAFLEATNRLVPTGRMSEATEVAALVCYLISPAAAGLTGTQLRVDGGGHCLAGLP-NLAPPEHTLRGRNPAVTPCVPR +>tr|U2RM60|U2RM60_9ACTN KR domain protein OS=Propionibacterium acidifaciens F0233 GN=HMPREF0682_2684 PE=4 SV=1 +-DETFLQSWLARIPMGRPGTTTEIVPLASYLLSSRSQSVTGQVIALDGGFSL-PNLP-SVQLHRrTSA------------- +>tr|A0A1C6QX72|A0A1C6QX72_9ACTN 3-oxoacyl-[acyl-carrier protein] reductase OS=Streptomyces GN=YUWDRAFT_05734 PE=4 SV=1 +-GPDHRRGWISRIPAGRVGRPPEVASVLGHLLSGSAARVTGAVLRVDGGFGL-GDVA-PLRPGFpEPVAVDSVEEAR---- +>tr|A0A229T8B2|A0A229T8B2_9PSEU Short-chain dehydrogenase OS=Amycolatopsis sp. KNN50.9b GN=CF166_24080 PE=4 SV=1 +-DPAFVSVSMRRVPVAHPSEPEDLAAVIAYLASPASAMISGARLRVCGGLATLGPLP-ALTGSSRHAVRATATAVAR--- +>tr|A0A1X7E0S0|A0A1X7E0S0_9RHIZ NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Rhizobium oryzae GN=SAMN02982989_3261 PE=4 SV=1 +--KTMFDNAADKLPVNLVGLPEHIAVQITAFQL--NPYITGSIVYVDGGGAL---------------------------- +>tr|A0A0J8RC22|A0A0J8RC22_COCIT 2-deoxy-D-gluconate 3-dehydrogenase OS=Coccidioides immitis H538.4 GN=CIHG_00229 PE=3 SV=1 +-DAARNDGIMARIPAGSGVNLRISRAWLCFLPAKPVRMSPGRLSVSTvDGW------------------------------ +>tr|A0A0J5P2U7|A0A0J5P2U7_9PAST Short-chain dehydrogenase OS=Muribacter muris GN=RO21_11030 PE=4 SV=1 +-EGEQRMKIIADIEAGIPLGhfgePIDVAYGILYLASNESRYLTGIELTIDGGILAGSEAKPK--------------------- +>tr|A0A137XH17|A0A137XH17_OCHAN Uncharacterized protein OS=Ochrobactrum anthropi GN=AYJ56_17440 PE=3 SV=1 +------EKLTAGLAMGEWVPPQEIGALIGFLATGTCRHMTGCTIDFNGASYIR--------------------------- +>tr|B3Q3G3|B3Q3G3_RHIE6 Putative 3-oxoacyl-[acyl-carrier protein] reductase protein OS=Rhizobium etli (strain CIAT 652) GN=RHECIAT_PC0000643 PE=3 SV=1 +------EAAVGDIPIGEMAEPGEIAETGGLPASSVTG--IGQRRDIRRQwrqlhqveQFQR--------------------------- +>tr|E4TV38|E4TV38_MARTH Short-chain dehydrogenase/reductase SDR OS=Marivirga tractuosa (strain ATCC 23168 / DSM 4126 / NBRC 15989 / NCIMB 1408 / VKM B- +------GFALDDIALTKLTEPEDVSPTIAMLMSGLMDHATGTTIDINAGSYVH--------------------------- +>tr|N4VBM4|N4VBM4_COLOR Short-chain dehydrogenase reductase sdr OS=Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF +--AAARKVLEAGKSThNGYGRPEDIADVAGLIVSDSAHWINGSVVAANGG------------------------------- +>tr|A0A120A3X6|A0A120A3X6_BACSE Putative 3-oxoacyl-(Acyl-carrier-protein) reductase, FabG-like OS=Bacteroides stercoris GN=fabG_1 PE=4 SV=1 +-TPEGYKAMVAQEPIGRLGKVEEMVSSMLWLCSEGAGFMVGHALVMDSGQTVG--------------------------- +>tr|R5EGV3|R5EGV3_9GAMM Uncharacterized protein OS=Succinatimonas sp. CAG:777 GN=BN779_01816 PE=4 SV=1 +------YLTEGYQPYG-LIPTHVISEAICFLLGPNAKYYSGSCVKIPAGVCC---------------------------- +>tr|A0A0N1H5M1|A0A0N1H5M1_9EURO Putative NADP-dependent mannitol dehydrogenase OS=Phialophora attae GN=AB675_7294 PE=4 SV=1 +--ENVKDEAHRMAVLGRQGDVKELKAVYLWLASSAGGFATGSDVLVDGGYTLHEWGP-SEGHDR---------------- +>tr|A0A1L9SQV1|A0A1L9SQV1_9EURO Uncharacterized protein OS=Penicilliopsis zonata CBS 506.65 GN=ASPZODRAFT_129952 PE=4 SV=1 +--PNeWQKKWLDMIPANRMADPYELKGVSSAA--FFCLPFASKEIlLTSQGFCLPCLRR-FELyHRR---------------- +>tr|D6U054|D6U054_9CHLR Short-chain dehydrogenase/reductase SDR OS=Ktedonobacter racemifer DSM 44963 GN=Krac_2981 PE=4 SV=1 +-TEDRLKQISTTVPLSRLGKPEEVASVVAFLASSDASYITGEEIHIDGGRGSVISQH-FLGNRERHSQGVSL-------- +>tr|A0A0F9SVM1|A0A0F9SVM1_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0426100 PE=4 SV=1 +-EEDELRHILSAQAIPELLTPADLAGTFLFLGSPAAAAMTGQALVVSRGEVMH--------------------------- +>tr|A0A0A1GEA1|A0A0A1GEA1_9PSED 3-hydroxybutyrate dehydrogenase OS=Pseudomonas sp. MT-1 GN=MT1_2310 PE=4 SV=1 +-EAEELVAVLAAQAIPELLTPADLSGTFLFLGSPLAAALTGQALSVSHGEVMH--------------------------- +>tr|A0A063TS84|A0A063TS84_BORBO KR domain protein OS=Bordetella bronchiseptica OSU553 GN=L533_1591 PE=4 SV=1 +-EPAMRAEVLQHVSLHRTVPMADIARTALFLACGTGRSITGQCMNICAGVQTL--------------------------- +>tr|A8LED9|A8LED9_FRASN Short-chain dehydrogenase/reductase SDR OS=Frankia sp. (strain EAN1pec) GN=Franean1_3203 PE=4 SV=1 +---DDVEHFTASQLTGRLIDPAEVAETIAFCCSVAGGVLTGSVVSAEGGFR----------------------------- +>tr|A0A010QZ38|A0A010QZ38_9PEZI L-xylulose reductase OS=Colletotrichum fioriniae PJ7 GN=CFIO01_09197 PE=3 SV=1 +-PKELMEHWLSMIPGGRVCHPAELRGPELMIERCDRWRI-HIAVAYDQAGGSPTDWM----------------------- +>tr|F9X1G6|F9X1G6_ZYMTI Uncharacterized protein OS=Zymoseptoria tritici (strain CBS 115943 / IPO323) GN=MYCGRDRAFT_31902 PE=4 SV=1 +-PKEWRDHWSLLVPAGRNADPAELKGAYVFLASDASSYMTGKSHPVLLVKAALTNRR----------------------- +>tr|A0A074Y486|A0A074Y486_9PEZI Uncharacterized protein OS=Aureobasidium subglaciale EXF-2481 GN=AUEXF2481DRAFT_43042 PE=4 SV=1 +-PAELMDKWLSMVPCGRIAQPAELKAVCRKCMRSE----DRTKMIAALRVPCK--------------------------- +>tr|A0A133KEM5|A0A133KEM5_BACCO Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Bacillus coagulans GN=HMPREF3213_03135 PE=4 SV=1 +-LKPLIEQWNKMAPLHRMGKPEELQSICVYLAGDTSTFTTGADFIVDGAFTCI--------------------------- +>tr|S4MHF4|S4MHF4_9ACTN Putative Bacilysin biosynthesis oxidoreductase BacC OS=Streptomyces afghaniensis 772 GN=STAFG_6967 PE=3 SV=1 +-RPPNAPPWRPASPPAAWSAPARSRAPSPTWRAPCPAPPraprsPSTAACRACGCA----------------------------- +>tr|L1KS66|L1KS66_9ACTN Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Streptomyces ipomoeae 91-03 GN=STRIP9103_00354 PE=4 SV=1 +--PSRIPRARSPVPPQVLVSPST-AACTVYGSGPASDLPhe----------------------------------------- +>tr|A0A060NRR7|A0A060NRR7_9BURK Dehydrogenase with different specificities related to short-chain alcohol dehydrogenase OS=Comamonadaceae bacterium A1 GN=SRAA_ +QSPENFHLASRINLRRQPIAPQDVAKTCLFMAE--TPSICGTTLCVDNGQHLVPLNQ----------------------- +>tr|A0A0N1LNK7|A0A0N1LNK7_9PROT Uncharacterized protein OS=alpha proteobacterium AAP38 GN=IP70_06530 PE=4 SV=1 +QTEEDFQTAHATAPLGRGSTPADISALVAYCLE--APLMSGRTITVDGGQHLQPRNR----------------------- +>tr|A0A0H4VFM2|A0A0H4VFM2_9SPHN Putative oxidoreductase protein OS=Erythrobacter atlanticus GN=CP97_07450 PE=4 SV=1 +QSAQEADRSHTLNLLQRRTGVAEVADAALFLAE--GPLASGQNIHVDSGQHLLDQTR----------------------- +>tr|A0A0L6T8K6|A0A0L6T8K6_9BURK Uncharacterized protein OS=Methylibium sp. NZG GN=AD742_12230 PE=4 SV=1 +IDDARLQRMAALSLTGRTVQPTDVADAVAFALG--NAALTGSTLMIDAGYHLQPMAR----------------------- +>tr|W0AJI2|W0AJI2_9SPHN Uncharacterized protein OS=Sphingomonas sanxanigenens DSM 19645 = NX02 GN=NX02_28610 PE=4 SV=1 +QSRDNFEKAHRMTALGTGVTVDDLVAALRFLIA--TPTITGQTIAIDAGQRFLGLPR----------------------- +>tr|A0A1G0Z1D5|A0A1G0Z1D5_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_44_16 GN=A2017_05610 PE=4 SV=1 +MENSKMEKTLKSVPMAKAVSMDDLTNACLFLAE--NNSITGQILYVDGGQHLHHGYN----------------------- +>tr|A0A1S6FFR3|A0A1S6FFR3_9SPHN Short-chain dehydrogenase OS=Sphingomonas sp. LM7 GN=BXU08_01235 PE=4 SV=1 +QTPEEFSEHARQNLLQRPVALDDIAATVEHLLT--CRSITGQNVFVDCGQRFLQRDG----------------------- +>tr|E4N4U3|E4N4U3_KITSK Putative fatty acid synthase OS=Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-60 +-SDALRATCAAAAPLGGVGHEDDLARLVGFLASPQSRWISGQCLLADGGLSVGRAMLT---------------------- +>tr|A0A0B5EGM8|A0A0B5EGM8_STRA4 Beta-ketoacyl synthase OS=Streptomyces albus (strain ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 / NBRC 107858) GN=SLNWT_011 +----------------AAATPRALAQLTAFLLGDTAAALDGHLLTLATPAPAHEPATA---------------------- +>tr|A0A1V4A9M7|A0A1V4A9M7_9ACTN Uncharacterized protein OS=Streptomyces tsukubensis GN=B1H18_13335 PE=3 SV=1 +-PAAVPGGGADTSELMrRTLSTPDAAKLIVHLLHEDTGFITGQTIVADGGISIGGMQGMRLNSR----------------- +>tr|E3RFT6|E3RFT6_PYRTT Putative uncharacterized protein OS=Pyrenophora teres f. teres (strain 0-1) GN=PTT_06605 PE=4 SV=1 +------VFGTGQVPQGRMGGFNDVGGMILFLVGKGGAYVNGAVQLSDGGRVGVFPGT----------------------- +>tr|A0A178DVJ8|A0A178DVJ8_9PLEO NAD-P-binding protein OS=Pyrenochaeta sp. DS3sAY3a GN=IQ07DRAFT_142507 PE=4 SV=1 +-PEQYYVEAQATTALAEPVPVRAVAMAILSLASHNFsSHIHGQIVNVDGG------------------------------- +>tr|A0A090MI52|A0A090MI52_9HYPO WGS project CBMI000000000 data, contig CS3069_c001773 OS=Fusarium sp. FIESC_5 CS3069 GN=BN850_0067940 PE=4 SV=1 +-ESgTvKWVESESTVAQKKAVDIDGIAKMCLVLASEKWsPSVTGQNVRLNGG------------------------------- +>tr|A0A1L7W069|A0A1L7W069_GIBIN Uncharacterized protein OS=Fusarium proliferatum ET1 GN=FPRO_11496 PE=4 SV=1 +-SSgAlRWIESEATVAQKKAVDVEGIAKMCLVLASEKWsPSVTGQNVRLNGG------------------------------- +>tr|A0A126Z048|A0A126Z048_9MICO Uncharacterized protein OS=Frondihabitans sp. PAMC 28766 GN=AX769_09260 PE=4 SV=1 +-SPEVSEQLRHLQPVsGGAQAADSVAKVVCWTLSDEALDLSGAVIPADGGWTL---------------------------- +>tr|A0A0R1JWM4|A0A0R1JWM4_9LACO Short chain dehydrogenase OS=Lactobacillus namurensis DSM 19117 GN=FD30_GL000359 PE=3 SV=1 +---------------KRFAsgpqVIARLADRAALSRRPKTRYHA-------GAGS----------------------------- +>tr|H3FJZ4|H3FJZ4_PRIPA Uncharacterized protein OS=Pristionchus pacificus GN=WBGene00112153 PE=4 SV=1 +--EEAVAAAATTVPVGRCGVLEELGNISAFICSDYGNFINGAIIDIDGAQQHFNH------------------------- +>tr|A0A1X7NNJ0|A0A1X7NNJ0_AZOLI NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Azospirillum lipoferum GN=SAMN02982994_1390 PE=4 SV +--VKVGATEADQIPLRRHGRMDELRNLLVFLMADGCDYLTGQTIGIDGGHHLAAP------------------------- +>tr|V4YJZ2|V4YJZ2_9PROT 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Betaproteobacteria bacterium MOLA814 GN=fabG_3 PE=3 SV=1 +LSPKALAAKQEALLKPKVLEVEEIMHAINFFASPLARNISCQTVYFGG-------------------------------- +>tr|A7H4M9|A7H4M9_CAMJD NAD dependent epimerase/dehydratase family protein OS=Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.9 +VPQNKLDILLNQQAIKRFGEFEDVLNVIEFFLDEKSGFITSQVVYLGG-------------------------------- +>tr|C4RL58|C4RL58_9ACTN Short-chain dehydrogenase/reductase SDR OS=Micromonospora sp. ATCC 39149 GN=MCAG_05299 PE=4 SV=1 +VPQRKIDELVARQAIQRICTMPDIVGPVEFLIGQQSAFVTGETIFLGG-------------------------------- +>tr|A0A0M9DXE3|A0A0M9DXE3_9DELT Oxidoreductase OS=Candidatus Magnetomorum sp. HK-1 GN=MHK_009834 PE=3 SV=1 +VNlsDEIMNDILEHTISKAWLEMEDVWHTIDFLISKKSEKISGQTIFLGG-------------------------------- +>tr|A0A1F9HB44|A0A1F9HB44_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFCSPLOWO2_02_FULL_40_36 GN=A3I69_03160 PE=4 SV=1 +FSLEQRKKIIAGSGFQKNVTTQDVFFTLNFILSQNSHAMTGQVITLGG-------------------------------- +>tr|N8VHE4|N8VHE4_9GAMM Uncharacterized protein OS=Acinetobacter sp. CIP 102159 GN=F974_00835 PE=4 SV=1 +IPFERQKRLKEATLNHKFCQVQEIANTALWLADKAPNCLSGEVFDLNNGVNYR--------------------------- +>tr|A0A1P8KKD4|A0A1P8KKD4_9PROT Short-chain dehydrogenase OS=Arcobacter sp. LPB0137 GN=LPB137_03815 PE=4 SV=1 +NSEQRKKEFKKTVSSGRFAQPEEVAKAIVWLATECPVYINGITLDINDCSYAR--------------------------- +>tr|I0H4L0|I0H4L0_ACTM4 Putative short-chain dehydrogenase OS=Actinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NCIMB +---HMYAAGYYYNALPtPMLEPDAVARVAVFLNSELAEFVTGQHFFVDAGHSVLPRS------------------------ +>tr|A0A1A9I2H8|A0A1A9I2H8_9BACT Uncharacterized protein OS=Niabella sp. BS26 GN=A8C56_13590 PE=4 SV=1 +---DEVAAHLaKSDALGlPWLKAEDVAPAVAFLTSSAADKITGAVYDVAGGTSPVYTS------------------------ +>tr|K6WGP0|K6WGP0_9ACTN Putative oxidoreductase OS=Gordonia rhizosphera NBRC 16068 GN=GORHZ_126_00430 PE=3 SV=1 +---ETSDEVVktTQHTLPvGSFAPQHISDALLYLVSDGAQMISGTALDVTAGMSTQWSA------------------------ +>tr|W9ARI5|W9ARI5_9MYCO Carveol dehydrogenase OS=Mycobacterium cosmeticum GN=BN977_00291 PE=3 SV=1 +---DAEEVFAKGRPRPGLLDPQDVADTVLYLVTDRVKCRSGESITLANGMD----------------------------- +>tr|A0A1E4I7A5|A0A1E4I7A5_9PSEU 3-ketoacyl-ACP reductase OS=Pseudonocardia sp. SCN 72-86 GN=ABS81_08000 PE=4 SV=1 +---HPNLGGMFTNILPlEQAEPRDISDTVLFLASDESRFFTAHELSPDAGVTEY--------------------------- +>tr|A0A1H5PYY3|A0A1H5PYY3_9ACTN SDR family mycofactocin-dependent oxidoreductase OS=Jiangella alba GN=SAMN04488561_6935 PE=4 SV=1 +---DYLAATRQWHVLRnrPALHPSAVADVVSWLCGHDARFITGTAVPVDAGHLVLPGF------------------------ +>tr|A0A0A0DXB3|A0A0A0DXB3_9SPIO Uncharacterized protein OS=Spirochaeta odontotermitis GN=JY97_11445 PE=4 SV=1 +---EAKEQFFQGHMIQdPEVTPEDIGRAVLWLASEDSRCIHGNMITVDSGWTAQAP------------------------- +>tr|A0A1Q8KNI6|A0A1Q8KNI6_9PSEU Short-chain dehydrogenase/reductase SDR OS=Pseudonocardia sp. Ae707_Ps1 GN=Ae707Ps1_2356 PE=4 SV=1 +---EVHKR-WLHDQLLaEVLSIGEITGALMWLLGDDARRVTGHCLAVDGGALAR--------------------------- +>tr|X7V9X0|X7V9X0_9MYCO (-)-trans-carveol dehydrogenase OS=Mycobacterium sp. MAC_080597_8934 GN=L841_2804 PE=3 SV=1 +-----------------YVEPADISNAILFLVSTTRATSPGSHYRSTVAPSS---------------------------- +>tr|V5II76|V5II76_IXORI Putative mitochondrial/plastidial beta-ketoacyl-acp reductase OS=Ixodes ricinus PE=2 SV=1 +--QTLLQRLQYMIPLRRIADPLEISETIVFYVQPEKPYLHDRIYKLyvAGGKAC---------------------------- +>tr|A0A1A5WMN2|A0A1A5WMN2_9GAMM Dehydrogenase OS=Aeromonas dhakensis GN=A9196_03980 PE=4 SV=1 +-REAMLGRAAASLPAGRHGRAEDLAAGYLLAID--NPFMTGATIDIDGGALIN--------------------------- +>tr|A0A0S4J1Y0|A0A0S4J1Y0_BODSA Short chain dehydrogenase, putative (Fragment) OS=Bodo saltans GN=BSAL_75060 PE=4 SV=1 +---GFLAT--mPSYALNRMATPDETANIFLFLASKQGLLINGTAQRADAACI----------------------------- +>tr|X8DJ73|X8DJ73_MYCXE Short chain dehydrogenase family protein OS=Mycobacterium xenopi 4042 GN=I553_1865 PE=4 SV=1 +MPEKLRDALIKAIPFRRLARPEEVAARCCSSLRMPrRSSLAR--WSVSAA--ALPWPDDKLPPIRSTEP------------ +>tr|A0A0B3BVL9|A0A0B3BVL9_9PSED 3-ketoacyl-ACP reductase OS=Pseudomonas flexibilis GN=fabG PE=4 SV=1 +IPLTIREAGRRMNALNQGGLPQDVAEAVAWLAQPSSGAVTGQVLRVCGQSLLGA-------------------------- +>tr|A0A158CH51|A0A158CH51_9BURK Acetyacetyl-CoA reductase OS=Burkholderia glebae GN=AWB82_05416 PE=4 SV=1 +--TLHQHQIVVTIPVRCLGRPDEVGLIVAWLASKESGFSAGADFSLNGGLHMG--------------------------- +>tr|I5C544|I5C544_9BACT Short-chain dehydrogenase/reductase sdr OS=Nitritalea halalkaliphila LW7 GN=A3SI_08461 PE=4 SV=1 +---EVKKNFEQMIPLGAMAPTRRWPSSppSCFLTAVNSLLVR---------------------------------------- +>tr|A0A1Q8JDP5|A0A1Q8JDP5_9PSEU 3-oxoacyl-[acyl-carrier protein] reductase OS=Pseudonocardia sp. Ae356_Ps1 GN=Ae356Ps1_0219 PE=3 SV=1 +---DVAGGIEdilergepgecwfvqpgrEPAPYGFRgvpspkgaGKPPEIGWQ----DH----------------------------------------------- +>tr|A0A0M2PER6|A0A0M2PER6_9BACI Short-chain dehydrogenase OS=Bacillus sp. SA1-12 GN=WQ54_23975 PE=4 SV=1 +----LYDSYQFKVPNAILGSHDDLAQCALYLSSDEAIYMNGADIRLDGGFMLHYVDKKMKKAD----------------- +>tr|C5EVB2|C5EVB2_9FIRM Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Clostridiales bacterium 1_7_47FAA GN=CBFG_05668 PE=4 SV=1 +----LYEGYQYKIPSGTVGSASDTAQLCGFLLDSRCRYVNGTEIRMDGGLLLHYIDEKANHRG----------------- +>tr|K9HAW4|K9HAW4_AGABB Uncharacterized protein OS=Agaricus bisporus var. bisporus (strain H97 / ATCC MYA-4626 / FGSC 10389) GN=AGABI2DRAFT_77756 PE=3 +MSNP-SEELRKRIPIGRFGRPQEVASIVELLVT--NAYMTNKVGTETSASLRYPTL------------------------ +>tr|A0A0D2H079|A0A0D2H079_9EURO Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.5, whole genome shotgun sequence OS=Rhinocladiella ma +LPGS--QELAARVPVGRLGKPEEIAETVIWIVR--TAYVHNKVVAVDGGMFIQ--------------------------- +>tr|A0A0B7KK65|A0A0B7KK65_BIOOC Uncharacterized protein OS=Bionectria ochroleuca GN=BN869_000013617_1 PE=4 SV=1 +--PDLHQKWVSLILQGKMGKPEDLMGPHILVVLLKSLHYWG--------------------------------------- +>tr|F2NQD1|F2NQD1_MARHT Short-chain dehydrogenase/reductase SDR OS=Marinithermus hydrothermalis (strain DSM 14884 / JCM 11576 / T1) GN=Marky_0912 PE=3 +-------EFHQRLPIGRPAPRTRSRAWCWSWRATWRRTCTGP-------------------------------------- +>tr|A0A1E5V287|A0A1E5V287_9POAL Uncharacterized protein OS=Dichanthelium oligosanthes GN=BAE44_0019709 PE=4 SV=1 +--TQLNEMINNCKAK-T-ANDDDVANAAVYLASDYGKSVTGQNLVLNNALYP---------------------------- +>tr|A0A1N6KJP9|A0A1N6KJP9_9BRAD 3-oxoacyl-[acyl-carrier protein] reductase OS=Bradyrhizobium erythrophlei GN=SAMN05443247_08379 PE=4 SV=1 +-------SLAKHIPLGRLGQATDLAPMALAVLSNsRELRSSSMAACR---------------------------------- +>tr|A0A1S1HIV9|A0A1S1HIV9_9SPHN Diacetyl reductase (S)-acetoin forming OS=Sphingomonas haloaromaticamans GN=budC PE=4 SV=1 +YQPEVAAGAARANPMHRMGDPErDIGGVVLFLAGEDARYLTGNTLFVDGGahIRRRPYQRRRLGPRHLRRGLIRQAAGAASPR +>tr|A0A0K2QVI1|A0A0K2QVI1_PORUM Xanthoxin dehydrogenase OS=Porphyra umbilicalis GN=PuXanDH PE=2 SV=1 +LPL---DKIKAMIPMGRLGEAGRGGGHGHLPRhRPGRGVRDGAHV------------------------------------ +>tr|A0A066WE84|A0A066WE84_9HOMO Uncharacterized protein (Fragment) OS=Rhizoctonia solani AG-8 WAC10335 GN=RSAG8_02438 PE=4 SV=1 +--HSNGDINSDGGGSRYLDSTQDLAGVLLFLASTVGARVTGARIESEATETHNITRW----------------------- +>tr|R7D989|R7D989_9FIRM Oxidoreductase short chain dehydrogenase/reductase family protein OS=Ruminococcus obeum CAG:39 GN=BN639_01634 PE=4 SV=1 +-DKVLWNEIMEQTPLKRWMTVEEAADWAYFMTV-TNRFCTGQNILIDGL------------------------------- +>tr|Q5BC99|Q5BC99_EMENI Putative oxidoreductase [Source:UniProtKB/TrEMBLAcc:Q8X186] OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / +--PEVEETWMRGALLGRLGVPDDFKAPSGLNEWSSKSAS----------------------------------------- +>tr|A0A1S1TNU9|A0A1S1TNU9_9RHIZ Short chain dehydrogenase OS=Mesorhizobium sp. ORS3428 GN=ORS3428_06565 PE=4 SV=1 +-DDDDFGKQVEGLILKRGPQLPEFGATIRYLWQ--ARSVTGQMIALDGGQHLAWQTP----------------------- +>tr|A0A1Z9I990|A0A1Z9I990_9EURY Uncharacterized protein OS=Euryarchaeota archaeon TMED164 GN=CBD24_00615 PE=4 SV=1 +-DEDSLKAVQSQSPLGFGPSANDVSESVVFLAN--SPSITGQTIFVDSGERFRQMRK----------------------- +>tr|A0A1Z9S3C5|A0A1Z9S3C5_9EURY Uncharacterized protein OS=Euryarchaeota archaeon TMED255 GN=CBE15_06745 PE=4 SV=1 +-TDRGFALAQSQSPLGYGPTPEDIAQTVILYFS--VPSLTGQVITVDSGEHMMNRSR----------------------- +>tr|Q9XE46|Q9XE46_ARATH NAD(P)-binding Rossmann-fold superfamily protein OS=Arabidopsis thaliana GN=At2g07640 PE=4 SV=1 +-PEEIENKTREYMPLYKLGEKWDIAMAALYLSCDSGKYMSGLTMVVDGGLCLSKPRHLAKEWRRGLGPGE---------- +>tr|U1QUH0|U1QUH0_9EURY Dehydrogenase OS=halophilic archaeon J07HX64 GN=J07HX64_02697 PE=4 SV=1 +--EVIEDVMLGQARTKEMMTPADVANLFVFGLSGYANHLNGADLLFDGGYTHTY-------------------------- +>tr|L9YQE2|L9YQE2_9EURY Uncharacterized protein OS=Natrinema gari JCM 14663 GN=C486_17929 PE=4 SV=1 +--EVVENVMLEHTRVTEMMEPYEVANLFVMGCSQHSKHLNGGDMTHDGGMSLTY-------------------------- +>tr|F0Z8T3|F0Z8T3_DICPU Putative uncharacterized protein OS=Dictyostelium purpureum GN=DICPUDRAFT_91189 PE=4 SV=1 +--SVAKDILLKHTVDGEFTTVEDVAEVAVNFSAIPNKCLTGQSLLVSHGWIME--------------------------- +>tr|A0A212SA62|A0A212SA62_RHOAC Enoyl-(Acyl carrier protein) reductase OS=Rhodoblastus acidophilus GN=SAMN06265338_11825 PE=4 SV=1 +MKTRFIAEHRPSSLLRRLAGVEEVANMEVYLCSAQASATNGAWV--RGGV------------------------------ +>tr|A0A146VKF3|A0A146VKF3_FUNHE L-xylulose reductase (Fragment) OS=Fundulus heteroclitus PE=3 SV=1 +-DPEKARSMTSRIPLGRFAGQKQQVMCLLSVCHQITHVFSQRpvFISADAKMSSR--------------------------- +>tr|L9KZR1|L9KZR1_TUPCH L-xylulose reductase OS=Tupaia chinensis GN=TREES_T100007383 PE=3 SV=1 +-DPHKAKAMLDRIPLGRFAGELGRSPAQSYIRVGGLRMYP---------------------------------------- +>tr|A4BTD2|A4BTD2_9GAMM 3-ketoacyl-(Acyl-carrier-protein) reductase OS=Nitrococcus mobilis Nb-231 GN=NB231_07687 PE=4 SV=1 +MPAKVLDKIKAKIPLGRLADPNEIGHSVVYLFE--NDYFNGRVLEAGGGCVCREAPTASLIP------------------ +>tr|A0A0D1EBZ8|A0A0D1EBZ8_9RHOB Putative short-chain type dehydrogenase/reductase OS=Jannaschia aquimarina GN=jaqu_38910 PE=3 SV=1 +-FDAVSEMIAQSTPIGiGHLEPEEVAASVMFFTTDATKNMTGEVLDVSYGSAATSV------------------------- +>tr|A0A165RX03|A0A165RX03_9RHOB (-)-trans-carveol dehydrogenase OS=Pseudovibrio sp. W74 GN=limC PE=3 SV=1 +-WDMVEEFTRRQHPLPvGVLEPRDIGKTVKFLCSEDAALVSGEAIDVSAGRTANWP------------------------- +>tr|L8F581|L8F581_MYCSM 3-oxoacyl-[acyl-carrier-protein] reductase OS=Mycobacterium smegmatis MKD8 GN=D806_6906 PE=3 SV=1 +-KEDLQGAKYWSTLRDvGLLPPQAMSEAVLWLASDESRWTTGLEMLVEGGHMLMPG------------------------- +>tr|Q0RX62|Q0RX62_RHOJR Short-chain dehydrogenase OS=Rhodococcus jostii (strain RHA1) GN=RHA1_ro09080 PE=3 SV=1 +-IDDVAEEFRRYQPQGvPWIPPQAITDALMFLVSDGAKHMTGETLSVAAGQNANGA------------------------- +>tr|M3VHC7|M3VHC7_9ACTN Putative oxidoreductase OS=Gordonia malaquae NBRC 108250 GN=GM1_045_00110 PE=3 SV=1 +-RDDVAPVFASLHAQPvPFIEPEEVTRVVLFLADELTSHITGTVVPIDAGAAARVS------------------------- +>tr|A0A1A1YF41|A0A1A1YF41_9MYCO 3-ketoacyl-ACP reductase OS=Mycobacterium sp. ACS1612 GN=A5724_02415 PE=4 SV=1 +-PDDLVRRMMKGNPIPaPWIEPEDVSRGLMYLVTDR-GVITGSVLEIGLGGSARIH------------------------- +>tr|A0A1H5ID94|A0A1H5ID94_9NOCA SDR family mycofactocin-dependent oxidoreductase OS=Rhodococcus jostii GN=SAMN04490220_7601 PE=4 SV=1 +-ADDVEPVFRSLHAQPvAWLDAFEITRVVLFFAAEGSAHISGTVLPVDAGNAARVT------------------------- +>tr|A0A1M3BLU6|A0A1M3BLU6_9ACTN 3-ketoacyl-ACP reductase OS=Solirubrobacterales bacterium 70-9 GN=BGO11_17895 PE=3 SV=1 +-LEDALPAFQSVNVLPvPYAETDDISDAVLFLASEQARYITGATLSAAIGVNAKNI------------------------- +>tr|A0A1G1LQK7|A0A1G1LQK7_9BACT Uncharacterized protein OS=Omnitrophica WOR_2 bacterium GWA2_47_8 GN=A2Z88_04640 PE=4 SV=1 +-PEVVQKFIEEKLPRKIMGKAEEIIPLILFLCSQAASMMGGCLVPIDAGEGKAF-------------------------- +>tr|A0A1F2U7L7|A0A1F2U7L7_9BACT Uncharacterized protein OS=Acidobacteria bacterium RIFCSPLOWO2_02_FULL_59_13 GN=A3H27_13170 PE=4 SV=1 +-PEAYQKFIEERLPRKVMGDASELIPMLALLCSEDASMMGGCLVPIDAGEGRAY-------------------------- +>tr|A0A1I8AFD8|A0A1I8AFD8_9BILA Uncharacterized protein OS=Steinernema glaseri PE=4 SV=1 +-TPENRSRFLAGIPLGRFCTPKDVAAAALYLASDEAEFITGTCIEITGtlvelveaGCDLILTTGGTGPARRDVTPEATLDAGT---- +>tr|A0A117NKX9|A0A117NKX9_9EURO Uncharacterized protein OS=Penicillium freii GN=ACN42_g10410 PE=3 SV=1 +--PAVKDAMLDSEGINNLHFSSIDESRLlhSWKENDIAYCWRGLLLP----------------------------------- +>tr|A0A212D9W3|A0A212D9W3_CEREH DCXR OS=Cervus elaphus hippelaphus GN=Celaphus_00001494 PE=4 SV=1 +-DPEFSQKLKERHPLRKFAEVEDVVNSILFLLSDRSASTSESGILVDAgatpprpaappsglqghqatllhaldhapdaihahsqtctprptvwshlhdttrqrptslqphtcptpptprtrphsstpnmwvpgdpvppapthcvvhsplkvrssrnimdlrlagrralvtgagkGI------------------------------ +>tr|U7PL39|U7PL39_SPOS1 Uncharacterized protein OS=Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) GN=HMPREF1624_08292 PE=4 SV=1 +-PETEGYDHPAFIPARRFGTDTDMAGTILYLASPAGGFCNGLTLVFDGGRLPVAT------------------------- +>tr|A0A0J8RWA2|A0A0J8RWA2_COCIT Short chain dehydrogenase/reductase family protein OS=Coccidioides immitis H538.4 GN=CIHG_06187 PE=4 SV=1 +-------DPSKLIPEGRAGADTDMAGIVLFLAITLRDVdlfRLPKISLDDAKEPSlhlTSP------------------------- +>tr|A0A0C4F9K6|A0A0C4F9K6_PUCT1 Uncharacterized protein OS=Puccinia triticina (isolate 1-1 / race 1 (BBBD)) PE=3 SV=1 +--SVLKDTMGLDIPEGRAGIDKEIAAAVLYLASKNQQYTSGSVILADGGVLNLMP------------------------- +>tr|A0A1R3RFI8|A0A1R3RFI8_ASPC5 Uncharacterized protein OS=Aspergillus carbonarius (strain ITEM 5010) GN=ASPCADRAFT_209822 PE=4 SV=1 +-GVSDGSFPSQMVPLTRAGSEQEFAGMVLWMASASGAYINGNITVTDGGRLSTVP------------------------- +>tr|A0A0B6AEF4|A0A0B6AEF4_BACAH Uncharacterized protein OS=Bacillus thuringiensis (strain Al Hakam) GN=BG07_2917 PE=4 SV=1 +--EDKMYQLAGTLSLNRISTPEDSAEAVLFQLT--QESITGQIYTIDNRQTL---------------------------- +>tr|G8WPK4|G8WPK4_STREN Short-chain dehydrogenase/reductase SDR OS=Streptomyces cattleya (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057) GN=SCATT_28150 PE=4 SV=1 +-DPVAYERFTAEFPGRELVRPEEIADVIAFLLSDQARGVTGVNLPVDRGQNAPTPQG----------------------- +>tr|M5BJH1|M5BJH1_THACB Uncharacterized protein OS=Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14) GN=BN14_01457 PE=4 SV=1 +--PELADKWASMNPLGRLGRPDELRGVVAWLASDASTFSYLLAVAITLGDGLTSN------------------------- +>tr|A0A1H2JRD2|A0A1H2JRD2_9ACTN NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Gordonia westfalica GN=SAMN04488548_1342420 PE=4 SV +ASPGVTEWISNSTPLGRMAERGGDRRGGripaqrPRLLRHRRDRAGRrrrrRLSRTAPGASKGYAEL-IHSSV----------------- +>tr|A0A024M4S1|A0A024M4S1_9MYCO Short chain dehydrogenase OS=Mycobacterium farcinogenes GN=BN975_04048 PE=4 SV=1 +-DADSIAAISRNVPLGRLAKPADIGWATAFFVVFGRLlyqrcvvggarWRGAAALPVHHD------------------------------- +>tr|G8G907|G8G907_EPICO Peroxisomal trans-2-enoyl-CoA reductase (Fragment) OS=Epinephelus coioides PE=2 SV=1 +IGPTIFKTAIPLSPAKRLGVPEEISSAVCFLLSPAASFISGATLRVDAGQSLYHSMW--EIPDHSAWPEAPEGENLD--- +>tr|A0A0B0I3Y1|A0A0B0I3Y1_9BACL Levodione reductase OS=Paenibacillus sp. P1XP2 GN=lvr_1 PE=3 SV=1 +-----------PAAVggaGHAGKRSRSRSLFGFGRIDPYHRHPGVHRR-SGVASPVRRLQ----PSR---------------- +>tr|A0A194VK60|A0A194VK60_9PEZI Dehydrogenase/reductase SDR family member 4 OS=Valsa mali GN=VM1G_11182 PE=4 SV=1 +--EEVMAKVAKELSVGFVASPEDVAEAYLYFIR--ADYANGATVVIGKWVFL---------------------------- +>tr|A0A1F8B9Q4|A0A1F8B9Q4_9BACT Uncharacterized protein OS=Candidatus Woesebacteria bacterium RIFCSPLOWO2_01_FULL_39_10b GN=A2892_01885 PE=3 SV=1 +---PQ--------YIGEVIDPKEIGKYAVYLCSEEANDITGKVFVLKKGKEPYEGY------------------------ +>tr|M7A8F8|M7A8F8_9ACTN Short-chain dehydrogenase OS=Gordonia sp. NB4-1Y GN=ISGA_3549 PE=3 SV=1 +--GEYTRYFISMMDDYPVATLDDISDAVLYLMSPQSRAITGMQMPIDMGNS----------------------------- +>tr|A4T1S3|A4T1S3_MYCGI Short-chain dehydrogenase/reductase SDR OS=Mycobacterium gilvum (strain PYR-GCK) GN=Mflv_5072 PE=3 SV=1 +--PTFLHSFAPMPFkpvardgkpgLQEFMTVEEVSDVVAWLAGDSSATISGSQIAVDRGTM----------------------------- +>tr|A0A0Q5QDN2|A0A0Q5QDN2_9ACTN Short-chain dehydrogenase OS=Williamsia sp. Leaf354 GN=ASG12_17890 PE=3 SV=1 +--EKYQPHFAPILNEPFFSTRDEVTSLVMYLCSDDARTITASTFSMDQGSV----------------------------- +>tr|A0A1B5ZF45|A0A1B5ZF45_9NOCA Putative NAD-dependent oxidoreductase OS=Rhodococcus sp. Br-6 GN=Br6_01820 PE=4 SV=1 +--PRYIDNYKWPLAGLSKCSVDDVSEVVLYLASDRSRTVTGSQMSLDLGIT----------------------------- +>tr|A0A0D2HH82|A0A0D2HH82_XYLBA Unplaced genomic scaffold supercont1.15, whole genome shotgun sequence OS=Cladophialophora bantiana CBS 173.52 GN=Z519_09572 PE +LPKEWTeALYARATAERRITEVHDVTDVVSWLAGPDSKLVNGNFVP----------------------------------- +>tr|F6HNU5|F6HNU5_VITVI Uncharacterized protein OS=Vitis vinifera GN=VIT_13s0019g02170 PE=3 SV=1 +--QDFFESNTPQTTRRAEGGL--IS---GGIPLPSCGFLHHRAGYLRGRWNDC--------------------------- +>tr|A0A212F231|A0A212F231_DANPL 3-dehydroecdysone 3alpha-reductase OS=Danaus plexippus plexippus GN=KGM_212779 PE=4 SV=1 +LDSDFIKNYKINTMGDRISSSEEVGHMILYLASDKAAGMTGMLTVI---------------------------------- +>tr|E7GJ29|E7GJ29_CLOSY Uncharacterized protein OS=[Clostridium] symbiosum WAL-14163 GN=HMPREF9474_00922 PE=3 SV=1 +------NISRKCGVLNRASLPEEIASLAAFLSTSTGKYVSGQTIIASACEEL---------------------------- +>tr|A5VEF2|A5VEF2_SPHWW Short-chain dehydrogenase/reductase SDR OS=Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273) GN=Swit_4328 PE=3 SV=1 +--------ISAKRSHEWLKAPEDVVPLALFMACQPDVGPTAQSFSLMRrl-------------------------------- +>tr|A0A0H4KT16|A0A0H4KT16_9RHOB Dehydrogenase with variable specificity OS=Marinovum algicola DG 898 GN=MALG_00952 PE=3 SV=1 +--------PPGFPEWERLKHPDEVGELALYMATRPIGGPTGQSFSLARrpL------------------------------- +>tr|A0A0S4PIV3|A0A0S4PIV3_9BACT 3-oxoacyl-[acyl-carrier protein] reductase OS=Armatimonadetes bacterium GXS GN=GXSOP10_12229 PE=3 SV=1 +---------GYVPDRSKMIRPESVAQVVVNLLTlPPDAH-VDELILLPQE------------------------------- +>tr|A0A1F9AH68|A0A1F9AH68_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RBG_13_61_14 GN=A2V67_10075 PE=3 SV=1 +---------RGWAEQSW-QPLELAGPLVTFLASgKADVLtgrwvgPKDDLPELIRriD------------------------------- +>tr|A0A178M5T7|A0A178M5T7_9CHLR Short-chain dehydrogenase OS=Chloroflexus islandicus GN=A6A03_02995 PE=3 SV=1 +------------VLNIFGTTAEETAELALRIVR---EGKNGQIFEVMPrhraI------------------------------- +>tr|A0A1V4MM28|A0A1V4MM28_9DELT Uncharacterized protein OS=delta proteobacterium ML8_D GN=AVO38_10710 PE=3 SV=1 +---------VEYNKKGYLKDPREVASLAVFLASsESDHLngyngTLGDYADLGWkr-------------------------------- +>tr|T1NTQ1|T1NTQ1_TRIUA Uncharacterized protein OS=Triticum urartu PE=4 SV=1 +SEFALREGELSRESFMLVADDDDAHGRRyVFEdVVMALLFVFGFWlktsvyCRLDNDNA----------------------------- +>tr|F8I372|F8I372_SULAT Short-chain dehydrogenase/reductase SDR OS=Sulfobacillus acidophilus (strain TPY) GN=TPY_1286 PE=4 SV=1 +LPLPQASRIQAQTRAGVWQSPEEVAEVIWRLLELPGDLMTGQVFYVNRGDVM---------------------------- +>tr|A0A1R0IR31|A0A1R0IR31_SULTH Uncharacterized protein OS=Sulfobacillus thermosulfidooxidans GN=BFX06_03180 PE=4 SV=1 +LTEEQKSRLIQQSASKKWIDPQDVAETLWDMIHNPPPS--GTVMMVN--------------------------------- +>tr|A0A1H8QTP7|A0A1H8QTP7_9ACTN Short-chain dehydrogenase OS=Streptomyces rubidus GN=SAMN05216267_103152 PE=4 SV=1 +--DARRRQLRETLPIRRVVGPEDVAAMGVHLML--NTALTGATYDVDGGQQF---------------------------- +>tr|A0A1F3T4F9|A0A1F3T4F9_9PROT Uncharacterized protein OS=Bdellovibrionales bacterium GWB1_55_8 GN=A2X94_07910 PE=4 SV=1 +--KKARNEPggispdalakqihrrFRSRPNGQLYTPISVHAIYLLHAL--SATFTSRLLELLVARK----------------------------- +>tr|A0A154LBP0|A0A154LBP0_9PROT Uncharacterized protein OS=Thalassospira sp. MCCC 1A01148 GN=AUQ43_16105 PE=4 SV=1 +FAEGEIEKHVQQTPVGKLIALEDLVKICFDISQPHWASLNGQVIDINGGRYV---------------------------- +>tr|A0A0G2K6H4|A0A0G2K6H4_RAT Peroxisomal trans-2-enoyl-CoA reductase OS=Rattus norvegicus GN=Pecr PE=1 SV=1 +LGQTMFEMAFENIPAKRVGLPEETLPfgVLPTVPRSTPSLPGQVHINVRRQARLCT-------------------------- +>tr|D9XT94|D9XT94_9ACTN Short-chain dehydrogenase/reductase family oxidoreductase (Fragment) OS=Streptomyces griseoflavus Tu4000 GN=SSRG_05097 PE=4 SV= +-GPRAGGPSSGPHPPRQVRRGRRDRRRR-RLPGQ-RRLLLR--------------------------------------- +>tr|B9T9R1|B9T9R1_RICCO Uncharacterized protein OS=Ricinus communis GN=RCOM_0057120 PE=4 SV=1 +---DIERLHISRTPLGRFADPDEMASAAIYFASDDASFITGQTLYVDGGRTVLAFVMPDKGKETSADP------------ +>tr|A0A212F231|A0A212F231_DANPL 3-dehydroecdysone 3alpha-reductase OS=Danaus plexippus plexippus GN=KGM_212779 PE=4 SV=1 +--MEELKDAKMSTISDRSSTSEEIGNLILYLASDKAVGMTGSNYVIDNGLLVLN-------------------------- +>tr|A0A1S4CVL5|A0A1S4CVL5_TOBAC tropinone reductase-like 3 isoform X2 OS=Nicotiana tabacum GN=LOC107823087 PE=4 SV=1 +-------LVFRGENLRlrhySIGSEQHKT-WPRLLPIWHQ-------------------------------------------- +>tr|R2SV00|R2SV00_9ENTE Uncharacterized protein OS=Enterococcus pallens ATCC BAA-351 GN=UAU_03196 PE=4 SV=1 +VNQEELNALAAGIPLGKIGDVSDISGCMEYIIN--APYVTGQTISPNGGFVM---------------------------- +>tr|A0A0L1HXQ9|A0A0L1HXQ9_9PLEO L-xylulose reductase OS=Stemphylium lycopersici GN=TW65_01850 PE=4 SV=1 +--PQVINEGLRMIPLGRQGNVKEIKGLFLQYGSTIPSLVLKLPAELRSIIYH---------------------------- +>tr|A0A0E1X5U5|A0A0E1X5U5_9RHIZ 7-alpha-hydroxysteroid dehydrogenase OS=Brucella pinnipedialis M292/94/1 GN=BALG_01829 PE=3 SV=1 +LTPEIERAMLKHTPLGRLGERRISPMRrcssvrppqhgsaVRFSRFPAAACRNSTDISLLrkqpiPT------------------------------- +>tr|W1Q812|W1Q812_OGAPD Putative oxidoreductase OS=Ogataea parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1) GN=HPODL_03 +-TKERVEFFKTQSAYGRLTEISDIVPIITFLAKD-GHWITGQNLFANNGFTAPF-------------------------- +>tr|R0A7V2|R0A7V2_9FIRM Uncharacterized protein OS=[Clostridium] bolteae 90A9 GN=HMPREF1085_03792 PE=4 SV=1 +-ETNRAEFNQRVERVplKRVGEPWEIGTMVAFLASDKCELAVGTCVDMTGGLLLGY-------------------------- +>tr|A0A0Q9RWC1|A0A0Q9RWC1_9ACTN Uncharacterized protein OS=Nocardioides sp. Soil796 GN=ASH02_08400 PE=4 SV=1 +ADPvRaeTYERLRQRTPGKRLPEPAHIVAAAFALID--NPGINAANLVVDAGMHL---------------------------- +>tr|A0A161UKI5|A0A161UKI5_9MICO Putative oxidoreductase OS=Microbacterium sp. TNHR37B GN=fabG2 PE=4 SV=1 +KPEGVLSGYESRTPGGALATMLDVVDATKFLLF--NRGVSAHSLNVDRGWRI---------------------------- +>tr|A0A239ND76|A0A239ND76_9ACTN Short-chain dehydrogenase OS=Streptomyces glauciniger GN=SAMN05216252_13382 PE=4 SV=1 +NEQLqdGA---RKMTLTGRLATMADIVDGCLFLLE--NPMANGIDLTLNGGIA----------------------------- +>tr|A0A0B2WX97|A0A0B2WX97_9HYPO Oxidoreductase OS=Metarhizium album ARSEF 1941 GN=MAM_04510 PE=4 SV=1 +------IRDLYARQGLSMCGADEVARTIVWLLSQDSHPVYGANINVGAGV------------------------------ +>tr|G4MPN0|G4MPN0_MAGO7 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase OS=Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) GN=MGG_02225 P +------EVAAQAQ-NAGCILPEEAAEAIVWLLSENCLQLNGIAVPIGEMD------------------------------ +>tr|R0IRG4|R0IRG4_SETT2 Uncharacterized protein OS=Setosphaeria turcica (strain 28A) GN=SETTUDRAFT_19988 PE=4 SV=1 +-------QQKPGGLFANPIDSAHISKVMVWLLSDTASHVNGINMLVGATT------------------------------ +>tr|A0A0D2FQX8|A0A0D2FQX8_9EURO Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.4, whole genome shotgun sequence OS=Rhinocladiella ma +------AVADMAKRGITLLEPEWVSDTIVWLLGEESAGISGVNIPIGASA------------------------------ +>tr|A0A094EMQ5|A0A094EMQ5_9PEZI Uncharacterized protein OS=Pseudogymnoascus sp. VKM F-103 GN=V499_02946 PE=4 SV=1 +---ELMAMELKKIPIGRLAESEEIAQAISYLASPMSSYMTGAGLVVDGGYTTPPRFP-FSRPYAAEPPA----------- +>tr|T1KZC5|T1KZC5_TETUR Uncharacterized protein OS=Tetranychus urticae PE=4 SV=1 +-PDEIWDNFAKMMPLKRVAEPIEMAQLIALVASDVSKNMTGSIVASDSGYLLGDPYS-------SGRPLVKLLLSHHKP- +>tr|T0K262|T0K262_COLGC Uncharacterized protein OS=Colletotrichum gloeosporioides (strain Cg-14) GN=CGLO_10902 PE=4 SV=1 +--EEAIAGFVQNQLVREVGTVQQTAEAYLFSMRC--SFATGQQFVIDGGYTY---------------------------- +>tr|A0A0L0NME7|A0A0L0NME7_9HYPO Glucose and ribitol dehydrogenase-like protein 1 OS=Tolypocladium ophioglossoides CBS 100239 GN=TOPH_00048 PE=4 SV=1 +--DSVTARLKGRMTTGAIGQVEDVAEAYLYLMKD--KNASGSVVETTGGTLL---------------------------- +>tr|A0A0F9X2L0|A0A0F9X2L0_TRIHA Short chain dehydrogenase OS=Trichoderma harzianum GN=THAR02_08975 PE=4 SV=1 +--EEIGKDIAKDTLTGIFAYAEDVAVRPQYILCK--RFQKEANSQRRKPTYT---------------------------- +>tr|A0A0B8MXZ2|A0A0B8MXZ2_9EURO Short-chain dehydrogenase OS=Talaromyces cellulolyticus GN=TCE0_011r00544 PE=4 SV=1 +--EDRIEAAARKALLGKLGTPEETAEAYIYLMRD--TTATGVFINNSGGELL---------------------------- +>tr|A0A0C3HAE5|A0A0C3HAE5_9PEZI Uncharacterized protein OS=Oidiodendron maius Zn GN=OIDMADRAFT_56479 PE=4 SV=1 +--SAQVAAISETLPQKKIGTVEEAAQSYIYLMKD--TNATGGVVNTKAKNY----------------------------- +>tr|Q9YC93|Q9YC93_AERPE Putative oxidoreductase OS=Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) GN=APE_1361.1 PE=4 S +-LENVWRrEVEMLSPLARSGGLDEFEEVIRMLV-RSPDYMHGATVVFDGASG----------------------------- +>tr|Q9V1Q9|Q9V1Q9_PYRAB Glucose-1-dehydrogenase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=PAB0245 PE=4 SV=1 +-MDEIWErEVIDRTPLKRTGRWSELGALIDFLLSENAEYMLGSTIVFDGAMT----------------------------- +>tr|A0A223SAM0|A0A223SAM0_9ACTN Uncharacterized protein OS=Nocardiopsis gilva YIM 90087 GN=CDO52_21935 PE=4 SV=1 +--EDFKKAAAEGIPVRRVGQPEDIANTVSFLTSEASGFVSGQVIYVAGGPSTDAPPAAPGRRPHGGPPAVPSPPGSPTP- +>tr|A0A1F7FGQ3|A0A1F7FGQ3_9BACT Uncharacterized protein OS=Candidatus Raymondbacteria bacterium RIFOXYD12_FULL_49_13 GN=A2519_03765 PE=4 SV=1 +--PG-Q----------TWGTIAGLLKAFRYLVE---SEATGQIMYCDQGLRLF--------------------------- +>tr|A0A0G4L408|A0A0G4L408_9PEZI Uncharacterized protein (Fragment) OS=Verticillium longisporum GN=BN1723_010999 PE=4 SV=1 +--RAKLeSIMNASTLTRSIGEPADVAEAYIYCMRD--NNVTGASIDSTSGHIL---------------------------- +>tr|A0A177C8R8|A0A177C8R8_9PLEO NAD(P)-binding protein OS=Paraphaeosphaeria sporulosa GN=CC84DRAFT_1151685 PE=4 SV=1 +--QAFFEGSKTSLFTGRVPTAEDVAESFIGIMKD--YNMDASMVRSDGGSLF---------------------------- +>tr|A0A0N0NR97|A0A0N0NR97_9EURO Glucose and ribitol dehydrogenase OS=Phialophora attae GN=AB675_8564 PE=4 SV=1 +--EQTRQYMAQHLLGKRVPKPEDAAEQYLASMRD--ANSTGTLYGTNGGELI---------------------------- +>tr|A2R8G7|A2R8G7_ASPNC Aspergillus niger contig An16c0230, genomic contig OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) GN=An16g07090 PE=4 SV= +--DMYMEMFRKGTVLGRVGAPEDVAEAYLWWGVR--ERGRELVVGDGGMGMR---------------------------- +>tr|A0A166VIT4|A0A166VIT4_9PEZI Short chain dehydrogenase/reductase family OS=Colletotrichum tofieldiae GN=CT0861_02648 PE=4 SV=1 +--EVMRTFLSNKSLLCRIGDAEDLAEAYLSIMKN--YFVTGTIMHVNGGLML---------------------------- +>tr|A0A078AFE5|A0A078AFE5_STYLE Dehydrogenase reductase sdr family member 4 OS=Stylonychia lemnae GN=Contig6085.g6510 PE=3 SV=1 +-----QKSRKQELNPKIYGQPSQIASIVATmCSED--GS------FVNGETYF---------------------------- +>tr|W9VKY4|W9VKY4_9EURO Uncharacterized protein OS=Cladophialophora yegresii CBS 114405 GN=A1O7_09104 PE=4 SV=1 +----------EKALLRSMEGMRSVANATAWLSSPGSGWLTGLVVPVDKGRNLNCVW------------------------ +>tr|A0A101QHA0|A0A101QHA0_STRAT Uncharacterized protein OS=Streptomyces antibioticus GN=AQJ23_03780 PE=3 SV=1 +VDPERRSYM-ANRALMGLGDGQQVADTIAFLAGPAADYINATTVHADGGVRY---------------------------- +>tr|A0A024G777|A0A024G777_9STRA Uncharacterized protein OS=Albugo candida GN=BN9_031580 PE=4 SV=1 +----------------FIKYGEDATNMVLHFVSDQIRCMKGVSVVLHENA------------------------------ +>tr|A0A0F3GNH9|A0A0F3GNH9_9BACT Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Candidatus Magnetobacterium bavaricum GN=MBAV_004278 PE=3 SV=1 +---------EKTNFRKKALDASEIADVIVYLLSKRSAVINGQIIVSDAGTMLNP-------------------------- +>tr|A0A1F6DUC8|A0A1F6DUC8_9BACT Uncharacterized protein OS=Candidatus Kaiserbacteria bacterium RIFCSPHIGHO2_02_FULL_55_17 GN=A3C94_01690 PE=4 SV=1 +-NAKdpaalegILAAIKKRMPAHELIPSEAVAEYIVHLAAGGARWVTGQVTDFDAGYTRNI-------------------------- +>tr|A0A1J5CU48|A0A1J5CU48_9BACT Uncharacterized protein OS=bacterium CG2_30_33_46 GN=AUJ93_02465 PE=4 SV=1 +---NMLKAYKLATPF--VVDQQEVGRVCVALASGYLKSLTGSVLHADGGFHV---------------------------- +>tr|A0A1J1EJB8|A0A1J1EJB8_THETH Enoyl-ACP reductase OS=Thermus thermophilus GN=fabL PE=4 SV=1 +--TKMYDRVAQTAPSGGTSPRRRWATSASSSSPPWRAASPGRWStwtraTTSWGWSWKGSPP----------------------- +>tr|A0A1L8S1W4|A0A1L8S1W4_9ENTE Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Enterococcus caccae GN=RU98_GL000802 PE=3 SV=1 +--DQLIKISEGRTPDKAGVTIEEVGNTCAFLVSELAAGIVGDIIYVDKGVHLT--------------------------- +>tr|W2S0I5|W2S0I5_9EURO Uncharacterized protein OS=Cyphellophora europaea CBS 101466 GN=HMPREF1541_04044 PE=3 SV=1 +----VEGNDAEVHLSNRAGMPEDISEAVEYLLG--AGFGEFsflQSIVLRGSVP----------------------------- +>tr|A0A0P0YG49|A0A0P0YG49_9PROT Short-chain dehydrogenase/reductase SDR OS=Asaia bogorensis NBRC 16594 GN=Asbog_01041 PE=3 SV=1 +-PAQAWKDRARTEVQPvGWLQPEDISPVAVFLASDASALTTGAEFEVNGGDSALM-------------------------- +>tr|A0A078ASB0|A0A078ASB0_STYLE Dehydrogenase reductase sdr family member 4 OS=Stylonychia lemnae GN=Contig14931.g15915 PE=4 SV=1 +----------TQKIPRIISEPHNVASIAAMITSDDGSFINGESHVIESKVL----------------------------- +>tr|H0E2V1|H0E2V1_9ACTN Putative rhamnulose-1-phosphate aldolase OS=Patulibacter medicamentivorans GN=PAI11_11160 PE=4 SV=1 +-PDQLEEHYRQRNTLKVLILPEDIAAATLHFASPaRSGKSTGNVLNVDGGVPAAYPR------------------------ +>tr|A0A0J9EAA4|A0A0J9EAA4_9RHOB Putative oxidoreductase OS=Candidatus Rhodobacter lobularis GN=AIOL_004543 PE=4 SV=1 +-EET----YMGGNLLGREVEARHVADGFVNLAL--MERTTGHVVTVDGGNTEAELR------------------------ +>tr|L8M1W1|L8M1W1_9CYAN Uncharacterized protein OS=Xenococcus sp. PCC 7305 GN=Xen7305DRAFT_00010380 PE=4 SV=1 +-VEE----YKTNNVLKVEVTSESVGELAVELCT-pLFANTTAAQIPIDGGNERVI-------------------------- +>tr|A0A1B5ZTD3|A0A1B5ZTD3_9FLAO Diacetyl reductase OS=Arenibacter sp. C-21 GN=budC PE=4 SV=1 +-VDELPAHYAKRNLLNEIIYPEDIANGVFACVA-ILDKTTGNIINVDGGMANAFVR------------------------ +>tr|A0A1G2Y8P8|A0A1G2Y8P8_9BACT Uncharacterized protein OS=Planctomycetes bacterium GWF2_50_10 GN=A2Y07_06015 PE=4 SV=1 +-PQEVIPYYVNKTHLKREIKGQDIADSVVFLCS-dKARVITGQVIVADSGQVMVR-------------------------- +>tr|A0A1M5KW73|A0A1M5KW73_9BACT Rhamnulose-1-phosphate aldolase/alcohol dehydrogenase OS=Aliifodinibius roseus GN=SAMN05443144_1358 PE=4 SV=1 +-FDeeestetlreTLADFYASRTLTRQPITLDQQTEAIYSLIS-sRYENTTGHIIPVDGGLKEAFLR------------------------ +>tr|A0A227SLY5|A0A227SLY5_CRYNV Cytoplasmic protein OS=Cryptococcus neoformans var. grubii Th84 GN=C355_04872 PE=4 SV=1 +----WVKEWEKRSPVSQFVTTYEIGRFVATPLSdkiGRMGFMAGSEIAIGGAS------------------------------ +>tr|A0A0U0W5X6|A0A0U0W5X6_9MYCO Short chain dehydrogenase OS=Mycobacterium bohemicum DSM 44277 GN=BN971_00980 PE=4 SV=1 +------GALAQLGALKRFGRPSEIAELLAFCASDKPGYLTGTDIICDGGVMAAMRPKDMLKLARSQ-------------- +>tr|C1AR26|C1AR26_RHOOB Uncharacterized protein OS=Rhodococcus opacus (strain B4) GN=ROP_02560 PE=4 SV=1 +------------FAAPG-PGDREVAAVASYLCAPAGMFVTGAAYVVDGARIAMIPHSL---------------------- +>tr|I0BSM8|I0BSM8_9BACL Short-chain dehydrogenase OS=Paenibacillus mucilaginosus K02 GN=B2K_32500 PE=3 SV=1 +------------------RDPFLVAPEIVALAAPDGSRFSSRLVLAGGSHGERT-TR-YRIER----------------- +>tr|N0B188|N0B188_9BACI Short-chain dehydrogenase/reductase SDR OS=Bacillus sp. 1NLA3E GN=B1NLA3E_11190 PE=3 SV=1 +------------------DDPANVAPYILELAKRKST-HEKKVIQLEDLSHSVK-AR-K--------------------- +>tr|A0A1E5LK25|A0A1E5LK25_9BACI Short-chain dehydrogenase OS=Bacillus solimangrovi GN=BFG57_07935 PE=3 SV=1 +------------------DDPANIAPYLVELATGDYE-VQKYVFDTSSISLEKT-YH-QS-------------------- +>tr|A0A1F3ZKN9|A0A1F3ZKN9_9PROT Uncharacterized protein OS=Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_62_17 GN=A3H35_08350 PE=3 SV=1 +------------------MFPHDIGRLATLMCSLPEEVNLFS---aiilpnhmpsfIGRG------------------------------- +>tr|A0A1H8PYU6|A0A1H8PYU6_9ACTN Short-chain dehydrogenase OS=Streptomyces rubidus GN=SAMN05216267_102776 PE=4 SV=1 +------------------QDPRQIGDELHRQF--VTSYEQGRLITAERSAASLL-GH-LGTED----------------- +>tr|A0A1Q8UXJ0|A0A1Q8UXJ0_BACPF Short-chain dehydrogenase OS=Bacillus pseudofirmus GN=BTR23_06150 PE=3 SV=1 +------------------EDPKDIAPILLDIASQVEL-GHGKIITADEWKLKLE-KN-LSTN------------------ +>tr|A0A178C0B4|A0A178C0B4_9EURO Uncharacterized protein OS=Fonsecaea multimorphosa GN=AYO22_06390 PE=3 SV=1 +--EP---MLAMTPAASRLGETEEMAYAAAFFCEERGRWMTGVCLAVNGGTLM---------------------------- +>tr|B5GK28|B5GK28_STRSH 3-alpha-(Or 20-beta)-hydroxysteroid dehydrogenase (Fragment) OS=Streptomyces sp. (strain SPB074) GN=SSBG_04637 PE=3 SV=2 +-PPSRRASRWAGSPSRRR-SPASCSSSppTKPLTSPAPPTSRTAECSPA--------------------------------- +>tr|B2J677|B2J677_NOSP7 Short-chain dehydrogenase/reductase SDR OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_R2173 PE=4 SV=1 +--EKLIPYWESISLGNKLCMPEDVADMVSYLLREEVKRINGSILLIDAGQSIH--------------------------- +>tr|A0A0K9N7K2|A0A0K9N7K2_9FIRM Alcohol dehydrogenase OS=Dorea sp. D27 GN=HMPREF0980_03184 PE=4 SV=1 +MTPEERAAFDAAQAKKRLIQPSEIAFWLGELLRDESTLMHGANIDATMGL------------------------------ +>tr|A0A0G4J4J7|A0A0G4J4J7_PLABS Uncharacterized protein OS=Plasmodiophora brassicae GN=PBRA_002436 PE=4 SV=1 +ELA--MPMTRGMLAKGRLIDPREIADVIYWICTQaQARVFHGAVLDASMGL------------------------------ +>tr|T0RYZ8|T0RYZ8_9DELT Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Bacteriovorax sp. DB6_IX GN=M901_1207 PE=3 SV=1 +LDQEQRDELISSLAKKRLIDPKEIANLCSFLISEQSQILHGAILDSSLGL------------------------------ +>tr|A0A0L9TVV8|A0A0L9TVV8_PHAAN Uncharacterized protein OS=Phaseolus angularis GN=LR48_Vigan02g046900 PE=3 SV=1 +----LKTVAMKTVPLRSYGTSDpALTSLARYLIHDSSEYVSGNNFIVDAGATI---------------------------- +>tr|A0A096RVL4|A0A096RVL4_MAIZE Uncharacterized protein OS=Zea mays GN=si606063d04 PE=3 SV=1 +----LSTVASKIVPLKEHGATDpALTSLVRFLIHEASSYVTGNIFIVDSDLLR---------------------------- +>tr|A0A0Q3FI94|A0A0Q3FI94_BRADI Uncharacterized protein OS=Brachypodium distachyon GN=BRADI_3g40050 PE=3 SV=1 +----LKTVVSKIVPLKTHGTTDpALTSLEPVKFIDNEALEA-----IMLGAHL---------------------------- +>tr|A0A1S3C2F6|A0A1S3C2F6_CUCME 3-oxoacyl-[acyl-carrier-protein] reductase FabG-like isoform X1 OS=Cucumis melo GN=LOC103495898 PE=4 SV=1 +----IKNVARRMNPLGTFGTSNpALTTTIRYLVHDSSKYVSEQERNRKkKKKSM---------------------------- +>tr|A0A094QCX0|A0A094QCX0_9ZZZZ Uncharacterized protein OS=freshwater metagenome GN=GM51_5865 PE=4 SV=1 +-DPEVRAKIESQVPMRRLGTMTEFAAFCMAFLDGSSRFTTGQFVAYAGGWA----------------------------- +>tr|A0A1D8AEI2|A0A1D8AEI2_9SPHN Uncharacterized protein OS=Novosphingobium resinovorum GN=BES08_27120 PE=4 SV=1 +-RhvpsGPWSRQLESESPAGRMGTMAELAAFCMPLLDGSSRYQTAQYFSFSGGWN----------------------------- +>tr|A0A1L8PH79|A0A1L8PH79_9LACT Uncharacterized protein OS=Alkalibacterium sp. 20 GN=AX762_01500 PE=4 SV=1 +---DLVKEMEKDIPMKHIAEPKEISNLLLYLSSDESIYSTGIEFVVDGGLIQVMYKAGEK-------------------- +>tr|Q8YQL6|Q8YQL6_NOSS1 All3805 protein OS=Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) GN=all3805 PE=3 SV=1 +IDTPANRQAMGTENADKWVKPESIGELICFLASEKAKDIRGAAIPIYG-------------------------------- +>tr|A0A1C1CV69|A0A1C1CV69_9EURO Uncharacterized protein OS=Cladophialophora carrionii GN=CLCR_10276 PE=4 SV=1 +-------ELFKAMPAARIGRAEDIVGAVLYLSSQAGGWAKTRRRLMSMEDAFAWMVA----------------------- +>tr|R7ZP94|R7ZP94_9BACT Short-chain dehydrogenase/reductase SDR OS=Lunatimonas lonarensis GN=ADIS_3602 PE=4 SV=1 +--------------FTKWVSPAEIAEAMHYAANSEA--LRNMTFKLYGG------------------------------- +>tr|A0A1Q3TBN3|A0A1Q3TBN3_9SPHI Uncharacterized protein OS=Sphingobacteriales bacterium 44-61 GN=BGO52_13740 PE=4 SV=1 +--------------FSKWVTPESIADIVYAHCDPSFDALREPLIKIYNK------------------------------- +>tr|A0A0G4L4J6|A0A0G4L4J6_9PEZI Uncharacterized protein (Fragment) OS=Verticillium longisporum GN=BN1708_017529 PE=4 SV=1 +-DQAKRQRREIHFPTGRFGEAVEQAQAVLFLASDEASFVNGHDMVVDGGMTKAYVTP---EGPASAAPMKENIPSS---- +>tr|A0A1X2LC17|A0A1X2LC17_9MYCO Uncharacterized protein OS=Mycobacterium vulneris GN=B8W69_03540 PE=4 SV=1 +--------WMTSQSGGRKAAPGEVADALAFLGSDAASYINGTNLLIDNGFSAAITTN---QIDYSSMPAVDALTNS---- +>tr|U1HPM8|U1HPM8_ENDPU Uncharacterized protein OS=Endocarpon pusillum (strain Z07020 / HMAS-L-300199) GN=EPUS_03294 PE=4 SV=1 +------DVQKANIGLERAGHPAEVAKVAGFLAPAASAATSPART-----SWSMV-------------------------- +>tr|H9UMQ3|H9UMQ3_SPIAZ Uncharacterized protein OS=Spirochaeta africana (strain ATCC 700263 / DSM 8902 / Z-7692) GN=Spiaf_2772 PE=4 SV=1 +LNSEQRARYSRLAGTRGLSNPDICAQLVWRIAEREEIFQNGAIINMQTYRK----------------------------- +>tr|F8EYG9|F8EYG9_TRECH Short-chain dehydrogenase/reductase SDR OS=Treponema caldarium (strain ATCC 51460 / DSM 7334 / H1) GN=Spica_0233 PE=4 SV=1 +LDEQARRYALGKAPGGILLQCEDIAETA--LAILHNPHQNGTIIALDKGLV----------------------------- +>tr|F4LL84|F4LL84_TREBD Short-chain dehydrogenase/reductase SDR OS=Treponema brennaborense (strain DSM 12168 / CIP 105900 / DD5/3) GN=Trebr_2249 PE=4 S +QPDSLKAVLARKMPTGAMIAPEAIAEAVLF--LLKTPEINGALLNVDAGWV----------------------------- +>tr|A0A1G3RJ60|A0A1G3RJ60_9SPIR Uncharacterized protein (Fragment) OS=Spirochaetes bacterium RIFOXYC1_FULL_54_7 GN=A3J97_03890 PE=4 SV=1 +LDPGKRDNFAKLAPGGRLTKPDRIAAFVVNLLLGDMALVSGSVINTDDGLY----------------------------- +>tr|A0A1G3LTV5|A0A1G3LTV5_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWB1_59_5 GN=A2Y38_19735 PE=4 SV=1 +LDDQTKIRLSAASPRGGLIPESEIAALVRYMVSGGMDLANGSIIVADRGLY----------------------------- +>tr|A0A1V6E2W9|A0A1V6E2W9_9SPIR 3-oxoacyl-(Acyl-carrier-protein) reductase FabG OS=Spirochaetes bacterium ADurb.Bin110 GN=fabG_6 PE=4 SV=1 +LDRETIIRHASLTATGSLSKADIIASIALNLIDAEPCIASGAVVNLDGGFA----------------------------- +>tr|B7FS72|B7FS72_PHATC Enoyl-acp reductase OS=Phaeodactylum tricornutum (strain CCAP 1055/1) GN=FABI PE=4 SV=1 +--EYAIDYSKANAPLEQDLYSDDVGNASLFLTSPMARTVTGVTLYVDNGLHS---------------------------- +>tr|Q0UVU3|Q0UVU3_PHANO Uncharacterized protein OS=Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) GN=SNOG_04121 PE=4 SV=2 +-NPEAVEKNLQFPVMKRRAEAEEVAHVIAFLLSEKASFVTGAVWNIDGGWPSAPQTH--------YSFFPKALPNGPPP- +>tr|W4VHV7|W4VHV7_9BACI 3-oxoacyl-[acyl-carrier protein] reductase OS=Gracilibacillus boraciitolerans JCM 21714 GN=JCM21714_1994 PE=4 SV=1 +---ESRKKHDPYTPIGRSGTGEDIARMVLFFCENKSDMITGTVVDVNGGLDVIHQQR-K--------------------- +>tr|A0A1S9R8W1|A0A1S9R8W1_9EURO Uncharacterized protein OS=Penicillium brasilianum GN=PEBR_41300 PE=4 SV=1 +---DTIQKIASHNPFKRIADPDEIAGAVSLLWKDESRWITGQVVKVNGGIGHTLAER----------------------- +>tr|A0A0P1B2Z3|A0A0P1B2Z3_9STRA Peroxisomal trans-2-enoyl-reductase OS=Plasmopara halstedii PE=4 SV=1 +--EMFVYAAEKITAAKRMGSVEEVSASVLYYLSPAGAYITgdtmhvdggwhllGPLIDVPEH------------------------------- +>tr|A0A0S8ESH9|A0A0S8ESH9_9DELT Uncharacterized protein OS=Myxococcales bacterium SG8_38_1 GN=AMJ63_12220 PE=4 SV=1 +--PELLANAEKSNPLKRLGTAEEVSHLITYLASRYADFIAgqtfyidggasiwGEQWFLPED------------------------------- +>tr|E4X740|E4X740_OIKDI Uncharacterized protein OS=Oikopleura dioica GN=GSOID_T00003201001 PE=4 SV=1 +--KEIFDKSAANVPKKRLGELYEGAnlsegtlsldliPQILFNLTDAVQYTTgwketldsrtklvL--------------------------------------- +>tr|B6QAJ7|B6QAJ7_TALMQ Polysaccharide deacetylase family protein OS=Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333) GN=PMAA_073690 PE +-ILPMYVS-TSNLRYRKhpkpsqdtSLQLKALVRATTFLASHsEAGHLSGECLGVDNVN------------------------------ +>tr|A2QAZ6|A2QAZ6_ASPNC Aspergillus niger contig An01c0400, genomic contig OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) GN=An01g13340 PE=4 SV= +-----FLI---IPEIHPltsssishSTTTDSISRTIAFLASHrAAGHLTGQCLNQNNNT------------------------------ +>tr|W7EDS8|W7EDS8_COCVI Uncharacterized protein OS=Bipolaris victoriae FI3 GN=COCVIDRAFT_18586 PE=4 SV=1 +-----------------lggDATDLSIISAMNILATSsSRGSVISL-------------------------------------- +>tr|A0A0G4PIA7|A0A0G4PIA7_PENCA Glycoside hydrolase/deacetylase, beta/alpha-barrel OS=Penicillium camemberti FM 013 GN=PCAMFM013_S016g000207 PE=4 SV=1 +-----------------srEASTQSIVAATAILGSAkPVRGIISL-------------------------------------- +>tr|W4JYI4|W4JYI4_9HOMO Uncharacterized protein OS=Heterobasidion irregulare TC 32-1 GN=HETIRDRAFT_435860 PE=4 SV=1 +-----------ETPTLPNGTRRDMGSLALMLIA--NWFINGETVLIDGGTLLKHPS------------------------ +>tr|A0A174SJN8|A0A174SJN8_9FIRM Sorbitol-6-phosphate 2-dehydrogenase OS=Faecalibacterium prausnitzii GN=srlD PE=4 SV=1 +--EDVRKFYMDQVPMRKGTGPEDVTKAVLYLIEQ--TCETGQAVPVTGGQVMLS-------------------------- +>tr|A0A0S8HHP2|A0A0S8HHP2_9BACE Uncharacterized protein OS=Bacteroides sp. SM23_62_1 GN=AMS27_09035 PE=4 SV=1 +--EDVRNYYEQLVPMKRGCTVADIMKTIYYLIDQ--QYETGQALPVTGGQIMLN-------------------------- +>tr|X7ZXS0|X7ZXS0_MYCXE Enoyl-(Acyl carrier ) reductase family protein OS=Mycobacterium xenopi 4042 GN=I553_5517 PE=4 SV=1 +-----IARVAATVPLGRLAKPADIGWAAAFLASDLASYISGATLAVHGGGEPRRIWP-RRAPTSKGATGMGLV------- +>tr|A0A0D2XP69|A0A0D2XP69_FUSO4 Uncharacterized protein OS=Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936) GN=FOXG_05 +-------AIAASVPVRRLGHPQEVANIAVMLDG--KNWISHRARYHLVWW------------------------------ +>tr|W1MG22|W1MG22_PSEAI Uncharacterized protein OS=Pseudomonas aeruginosa VRFPA03 GN=M770_25245 PE=3 SV=1 +--RWTSPTPCSSSPPTRRATSPGRPW--LWMAArccrRTAGWPEAA----GVR------------------------------- +>tr|A0A094DJ73|A0A094DJ73_9PEZI Uncharacterized protein (Fragment) OS=Pseudogymnoascus sp. VKM F-4515 (FW-2607) GN=V496_03342 PE=4 SV=1 +IPKETVEMQKASTPVQnRIGTVDDIAQIVLWMASEGSRWVTGQVVSASGGWAMY--------------------------- +>tr|A0A160VHR0|A0A160VHR0_9ZZZZ Oxidoreductase, short chain dehydrogenase/reductase family OS=hydrothermal vent metagenome GN=MGWOODY_Mmi1082 PE=4 SV=1 +--EAWVENTKKRNPMRRTTTPEDVAGTISMLLKPEADFINCSIIYCDGGESRSGTF------------------------ +>tr|D8SBE7|D8SBE7_SELML Putative uncharacterized protein OS=Selaginella moellendorffii GN=SELMODRAFT_444601 PE=4 SV=1 +----YEAAVLDRTPARRVGEPREVAAVAAFLALPASSYVTGQERHLLMVswcsdtLKvSGEVGHHDTLKRWS--------------- +>tr|T1GZE3|T1GZE3_MEGSC Uncharacterized protein OS=Megaselia scalaris PE=4 SV=1 +-SESANEAALSKIPMQRLGTK--MVGVYSFLVFKDAAYTTGRKSSCSYYFHRRY-------------------------- +>tr|A0A0F0KLS6|A0A0F0KLS6_9MICO Putative ketoacyl reductase OS=Microbacterium foliorum GN=actIII_1 PE=4 SV=1 +------RAMGAATPVGRSGTADEVASVIGFLADEAASYITGQLITVDGGQLHHRRTR-ALRPVTKERRELTMNENT---- +>tr|K1LD52|K1LD52_9BACT Cyclopentanol dehydrogenase OS=Cecembia lonarensis LW9 GN=cpnA_3 PE=4 SV=1 +LSENWYEEIpAMYAPSGRILWPSEIAAAAVYWLADESGPISGQVVDLEQHPLMGRN------------------------- +>tr|A0A143PNZ1|A0A143PNZ1_9BACT 4-formylbenzenesulfonate dehydrogenase TsaC1/TsaC2 OS=Acidobacteria bacterium DSM 100886 GN=tsaC1_2 PE=4 SV=1 +KGDEWVAEAVKTRPFGRLLEPADTAYAVAYYVSDAGACVTGSVMDLEQYPVGAPP------------------------- +>tr|A9KFX8|A9KFX8_COXBN Short chain dehydrogenase OS=Coxiella burnetii (strain Dugway 5J108-111) GN=CBUD_1365 PE=4 SV=1 +FPENWESKIpPTYAPSGRLIHPEDVARHAVFWASDVSAPANAVVYELEQYPVIGRN------------------------- +>tr|A0A059FU65|A0A059FU65_9RHOB Short-chain dehydrogenase OS=Hyphomonas johnsonii MHS-2 GN=HJO_02710 PE=3 SV=1 +-----------------QFHIDRVAPTLLYMVSDLSGDQTGKTLLAGGGWIGEVRF------------------------ +>tr|A0A1H0A4W0|A0A1H0A4W0_9PSEU NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Allokutzneria albata GN=SAMN04489726_5886 PE=4 SV=1 +-----------------LFTLDNCAALVAFLVSEASAYISGKVFGVQESNVEIYQS------------------------ +>tr|A0A1Q5GPW0|A0A1Q5GPW0_9ACTN Uncharacterized protein OS=Micromonospora sp. TSRI0369 GN=AMK25_28930 PE=3 SV=1 +-----------------GIAPEANVPLLLYLLSDLSVGLTGQVLRSYGSELMLTTH------------------------ +>tr|A0A074YAP8|A0A074YAP8_AURPU NAD(P)-binding protein OS=Aureobasidium pullulans EXF-150 GN=M438DRAFT_335658 PE=3 SV=1 +------EDFEGKVFAQRPGNDRDMGNAMLFVAS--NQYLSKASIRTWGSRARIADH------------------------ +>tr|A0A0E4CSX2|A0A0E4CSX2_9STRE Short chain dehydrogenase OS=Streptococcus varani GN=BN1356_01390 PE=4 SV=1 +-DPVVEEGRKALTANKRIGNTMDIANAVMYLASDRSDYTNGHELRVEGGFGIMMGDQ-TPKPGGRREFAVK--------- +>tr|G8YMK6|G8YMK6_PICSO Piso0_001215 protein OS=Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL Y-12695) GN=Piso0 +---------------RVPVPASEIFRTVKFLIE--SKWINGEDIRVDGGWRLVVNRPKGETDARSLAPGLE--------- +>tr|A0A0D0TH64|A0A0D0TH64_CRYGA Unplaced genomic scaffold supercont1.15, whole genome shotgun sequence OS=Cryptococcus bacillisporus CA1280 GN=I312_05139 PE=4 +---------------HRVSEPTEVSAAVSFILE--NPMLNDMDLRVDGGWRNSSNWg-GE-KDRESLVHMFG--------- +>tr|A0A1Y2B7F5|A0A1Y2B7F5_9TREE Uncharacterized protein OS=Naematelia encephala GN=BCR39DRAFT_528245 PE=4 SV=1 +---------------RVPLTADQITPTIHYIIE--NVGVNGIDIPVDGGWRLVSSKagLAGGEDPRSLAPGLE--------- +>tr|A0A0N1P2E6|A0A0N1P2E6_9EURO Putative NADP-dependent mannitol dehydrogenase OS=Phialophora attae GN=AB675_6410 PE=4 SV=1 +PVSDAKDQWLKQIPMGWLYSQILPRVQAL--T-DQPQVVLRVPMSLAPLW------------------------------ +>tr|A0A0F7TXT5|A0A0F7TXT5_9EURO Uncharacterized protein OS=Penicillium brasilianum GN=PMG11_10002 PE=4 SV=1 +-SPEDSAIMDIAPPLGRIGNFNDLTGAVIYLLSDASAYTTGADIPITGGLHIGR-------------------------- +>tr|A0A1V1TRU0|A0A1V1TRU0_9FUNG Uncharacterized protein OS=fungal sp. No.14919 GN=ANO14919_131970 PE=4 SV=1 +MTDEMRQARINQNLMKKEGTGWDVGYGRQSYYEAIKDI------------------------------------------ +>tr|A0A0P4R5L9|A0A0P4R5L9_9ACTN Oxidoreductase OS=Streptomyces sp. NBRC 110027 GN=TPA0598_03_08090 PE=4 SV=1 +------EMYYRELPWGRPLRLDEVAAACIELATaPQWAYATGQTYPLGAA------------------------------- +>tr|A0A0H5PAZ0|A0A0H5PAZ0_NOCFR 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Nocardia farcinica GN=fabG_28 PE=4 SV=1 +------ADYYARLPWGRALSIDEVAQTTVAVVCdPSWQYVSGQIIRLDAD------------------------------- +>tr|A0A0W1A9S8|A0A0W1A9S8_9GAMM 3-oxoacyl-ACP reductase OS=Legionella steigerwaltii GN=fabG_3 PE=4 SV=1 +--PAYQEKMAQIIPQGMMGETAQVAEAMDPLLSR-TSFMTGSVITVSGGLPLMRS------------------------- +>tr|G8T8K3|G8T8K3_NIAKG Enoyl-(Acyl-carrier-protein) reductase (NADH) OS=Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10) GN=Niako_3889 PE +----LIAQYKAFDILKMSPTLKQLGDTAAFLASDTGVAFNSHVVDVDCGKLN---------------------------- +>tr|A0A1A3EWL1|A0A1A3EWL1_9MYCO Short-chain dehydrogenase OS=Mycobacterium colombiense GN=A5623_20250 PE=4 SV=1 +----FAAKMAANSHRNRATTLVELAQAAVLVASDRASAMTGTVANLTGGIIV---------------------------- +>tr|A0A1H1TBZ0|A0A1H1TBZ0_9MICO NADP-dependent 3-hydroxy acid dehydrogenase YdfG OS=Microterricola viridarii GN=SAMN04489834_1737 PE=4 SV=1 +----FAGFLESLTTSRSLPSLDEVAEMAVFLAEGGARSMNGAVLNLTCGMSP---------------------------- +>tr|A0A1M7JTF0|A0A1M7JTF0_9BACT NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Chitinophaga jiangningensis GN=SAMN05444266_10912 P +----VAANYTRFDILKTVPTLKQLGETAAFLVSDNGMVFNSHIVDFDCGKLN---------------------------- +>tr|A0A0Q1DJ48|A0A0Q1DJ48_9FLAO Uncharacterized protein OS=Flagellimonas eckloniae GN=AAY42_01830 PE=4 SV=1 +----MQQFIVENkTAMKKLPSTENTANVVVLAASELASYMTGTVINQSVGHIL---------------------------- +>tr|A0A1V5F7G8|A0A1V5F7G8_9BACT 3-oxoacyl-(Acyl-carrier-protein) reductase FabG OS=Bacteroidetes bacterium ADurb.BinA395 GN=fabG_1 PE=4 SV=1 +VPETYQDSIKSQIPTQRFCEPEDILKTVEYIR--NTPYLNGSSIDLNGAL------------------------------ +>tr|E4ZNP1|E4ZNP1_LEPMJ Putative uncharacterized protein OS=Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) GN=LEMA_P041610. +---EMAKEHKEGLPAQRPGKDQDMAAAILFVVG--CQYLNGQTVTVDGGYAIQVG------------------------- +>tr|A0A0D2ULP9|A0A0D2ULP9_CAPO3 LtxD OS=Capsaspora owczarzaki (strain ATCC 30864) GN=CAOG_006400 PE=4 SV=1 +LPGALEEQGKQASLFKRLGTPDDIADLVDFLVGPTGGWITSQSVHTSGGVSFS--------------------------- +>tr|A0A0N0ZWA6|A0A0N0ZWA6_9FLAO Uncharacterized protein OS=Chryseobacterium indologenes GN=AOB46_07775 PE=4 SV=1 +MDERMKDMILSGYPLKEKLEGGDVAQVIDLCI-NGGKHFNGNHLFVDASHF----------------------------- +>tr|A0A0I9S977|A0A0I9S977_BACFG Uncharacterized protein OS=Bacteroides fragilis GN=EE52_0211930 PE=4 SV=1 +VDERILEQMVKDHPLKKLLTPEEVAQNIKFFV-DASQQVNGVKLQINAGTQ----------------------------- +>tr|A0A1H5VX06|A0A1H5VX06_PRERU Acetoacetyl-CoA reductase/3-oxoacyl-[acyl-carrier protein] reductase/17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoa +VEDFQLEQMKNAHPLKELLKPQEVAEVVCQLL-NTTQQLNGVEIPINAAQH----------------------------- +>tr|A0A232M1Q4|A0A232M1Q4_9EURO Uncharacterized protein OS=Elaphomyces granulatus GN=Egran_01981 PE=4 SV=1 +--AAFRQVWADRNPMRRMGTPQELTGPVVFLCSDiGSSYVNGADLVVDGECRSAAEAE-PTSPRRNLTSSTNLILNT---- +>tr|A0A126RPL0|A0A126RPL0_9SPHN Short-chain dehydrogenase/reductase SDR OS=Sphingobium sp. TKS GN=K426_15980 PE=4 SV=1 +IDTPTNRQDMPNEDFSKWVKAEAMAEVILFLASPAVRAVTGALIPVMRG------------------------------- +>tr|H2JLE3|H2JLE3_STRHJ Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Streptomyces hygroscopicus subsp. jinggangensis (strain 5008) GN=SHJG_1710 PE= +--DTIADRWERDAPLGWdRADVRRLTGPVLFLLSDLAATVTGEIVHADGGMHAVRMGV-GGQTFRKEAA------------ +>tr|A0A0H4WRH3|A0A0H4WRH3_9DELT Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Myxococcus hansupus GN=A176_000862 PE=3 SV=1 +--KALEQGWGTQAPLGWsAKNShDLVARTACAMLSDWLPSTTGEMIHVDGGYHAIGAPP-VAPEADEAPA------------ +>tr|A0A1G0ZXJ7|A0A1G0ZXJ7_9BACT Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Lentisphaerae bacterium RIFOXYC12_FULL_60_16 GN=A2498_06520 PE=3 SV=1 +--KRLMDWWQRMSPLPWdPDHDrAAVADAVGFLLGPGARRITGQVIHVDGGVSAVGGDW-LEHERINRPE------------ +>tr|A0A1Y0HHY0|A0A1Y0HHY0_9PROT Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Sulfurospirillum sp. SL2-1 GN=Sdiek1_0535 PE=3 SV=1 +--RMILNWNEINAPLRKnVTT-DEVGNSGMYLLSDLSSCVTGEVHYVDAGYSIMGMGM-DETDAEGHTV------------ +>tr|A0A0C3FE19|A0A0C3FE19_9HOMO Uncharacterized protein OS=Piloderma croceum F 1598 GN=PILCRDRAFT_824835 PE=4 SV=1 +-PTHKIQFIANIHPQKRMGLPTDIAPMIAFLASPEAAWISGQNIHINGVISSISPR------------------------ +>tr|K0C1G5|K0C1G5_CYCSP Short-chain dehydrogenase family protein OS=Cycloclasticus sp. (strain P1) GN=Q91_1122 PE=4 SV=1 +-PDVVLDEIRQQSAIHAFTLPEQVAWGICLLLAPEADAMAGSSLMLDSG------------------------------- +>tr|F3L0K5|F3L0K5_9GAMM Putative short chain dehydrogenase OS=gamma proteobacterium IMCC3088 GN=IMCC3088_941 PE=4 SV=1 +-IGEVLEQMASESTLKELTSVESIVWGISVLLDPNARAMAGSTLFMDSG------------------------------- +>tr|A0A084G9E6|A0A084G9E6_9PEZI Putative short chain protein OS=Scedosporium apiospermum GN=SAPIO_CDS4163 PE=4 SV=1 +FPEERLNAAIKANKLERFATVEDVAEQVKTFVV--SKSATGQNAIIDSGFSL---------------------------- +>tr|M7SI33|M7SI33_EUTLA Putative short chain protein OS=Eutypa lata (strain UCR-EL1) GN=UCREL1_7044 PE=4 SV=1 +FPEERLAMVKEANKLKRFTTMEDVAEQVRTFVV--SKTVTGQNTIIDAGFSL---------------------------- +>tr|A0A094A0X8|A0A094A0X8_9PEZI Uncharacterized protein OS=Pseudogymnoascus sp. VKM F-3775 GN=V491_03310 PE=4 SV=1 +-DEARAASILSRIPAGRWGKAEDFGGVVVWLAGAGSAHIDSVHLPSLDLSLSPVQYN----------------------- +>tr|A0A1A0XKF0|A0A1A0XKF0_9ACTN Uncharacterized protein OS=Gordonia sp. 852002-50816_SCH5313054-c GN=A5788_19385 PE=4 SV=1 +-------------------AADDVAKAAVHIVASDREDLHGQCLSFDGDTLAVWT------------------------- +>tr|A0A1E4GZE3|A0A1E4GZE3_9CAUL 3-hydroxyacyl-CoA dehydrogenase OS=Phenylobacterium sp. SCN 70-31 GN=ABS78_06285 PE=4 SV=1 +-------------------RADQPARFSVAMVTPAAAHVSGQIFGSSGENIILYS------------------------- +>tr|A0A1E3R5F1|A0A1E3R5F1_9MYCO Uncharacterized protein OS=Mycobacterium holsaticum GN=BHQ17_24375 PE=3 SV=1 +-------------------PPELCSPAAAFLAHESCPLN-GEVLMAGMGGVSRLA------------------------- +>tr|G8YDN2|G8YDN2_PICSO Piso0_002838 protein OS=Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL Y-12695) GN=Piso0 +-------SYDKTILNPPMEIpkdiavaLINITNSTIMVILYGVYNKHFHINPVYMNPW----------------------------- +>tr|J5E7W1|J5E7W1_9MYCO Dehydrogenase OS=Mycobacterium colombiense CECT 3035 GN=MCOL_V220251 PE=3 SV=1 +------EAIALSNGLADWANRTKsVTASCSSHPMHRASVRaRPCTCMVPPAPP----------------------------- +>tr|A0A1F8A5A3|A0A1F8A5A3_9EURO Short-chain dehydrogenase OS=Aspergillus bombycis GN=ABOM_004989 PE=4 SV=1 +-------KMQYYGGMRDWPTPRSsAGLMCtcSLMVLhtrPVSIFR---LLVL---------------------------------- +>tr|A2SW61|A2SW61_9MYCO Putative dihydrodiol dehydrogenase OS=Mycobacterium sp. CH-1 GN=phdE PE=3 SV=1 +----IADIMSTTNPLQYAQQPADHAGLYLLLASADnSRAVTGVVINSDGGLGVRGLNQ----------------------- +>tr|A0A0K1JC81|A0A0K1JC81_9RHOO TodD OS=Azoarcus sp. CIB GN=AzCIB_4413 PE=3 SV=1 +----LSELLESVLPIGRMPDVREYTGAYVFFANHGdAAPATGAVLNYDGGMGVRGLFS----------------------- +>sp|Q7N4V7|HCAB_PHOLL 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase OS=Photorhabdus luminescens subsp. laumondii (strain DSM +----SLESLSAILPLQFIPQPKDFTGPYVMLASRAnNRTLTGVMITADAGLSIRGIRQ----------------------- +>tr|A0A0Q6JRN1|A0A0Q6JRN1_9NOCA Uncharacterized protein OS=Rhodococcus sp. Leaf258 GN=ASH03_19375 PE=4 SV=1 +----YRQQFEWLAPLQHMPTPEEYGPLYAFLASRHNTVMTGQTVLADSGSLNRALIS----------------------- +>tr|A0A0J5Q5F4|A0A0J5Q5F4_9RHOB Uncharacterized protein OS=Puniceibacterium sp. IMCC21224 GN=IMCC21224_1574 PE=3 SV=1 +----LDDLMKQILPLEKAFYADEYAGAYVFFADRNdNGPATGAVLNFDGGIGMRGFMS----------------------- +>tr|A0A1A3JTE3|A0A1A3JTE3_9MYCO 3-(Cis-5,6-dihydroxycyclohexa-1, 3-dien-1-yl)propanoate dehydrogenase OS=Mycobacterium sp. 1165549.7 GN=A5626_01875 PE=4 SV=1 +----RAAEVAARTPLHVALTGEDHAFSYVFLTSDRTRGITGETVRPDGGFGLGAPTS----------------------- +>tr|T0J059|T0J059_9SPHN Uncharacterized protein OS=Sphingobium ummariense RL-3 GN=M529_21510 PE=4 SV=1 +----FMAMIRKVTLLDHLPTGAEYGPAYALLADPKQRILTGEIIMADQGLANRPIIS----------------------- +>tr|O69366|O69366_RHOER 2,3-dihydroxy-4-phenylhexa-4,6-diene dehydrogenase OS=Rhodococcus erythropolis GN=bphB PE=4 SV=1 +----IGEVMKQRSALHFEPAPEDYVAAYVLLAAKSqSRTVTGSVFDVSSFGTPTRPSG----------------------- +>tr|N1LZ45|N1LZ45_9NOCA 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase OS=Rhodococcus sp. EsD8 GN=EBESD8_9760 PE=4 SV=1 +----IRQMVRDNGALQIEVEPDDYVGAYLYLACRDdSATVTGTVVDVSSWGTPKRTDA----------------------- +>tr|A0A1Q5Q035|A0A1Q5Q035_9ACTO 3-(Cis-5,6-dihydroxycyclohexa-1, 3-dien-1-yl)propanoate dehydrogenase OS=Actinomyces nasicola GN=BSZ39_11395 PE=4 SV=1 +----HTGPPNPYLPLPDAPtDPSAYVAPFLMLADPRaSAMITGEIIRADGGLAARGFYP----------------------- +>tr|A0A1V4PU73|A0A1V4PU73_9ACTN 3-(Cis-5,6-dihydroxycyclohexa-1, 3-dien-1-yl)propanoate dehydrogenase OS=Gordonia sp. i37 GN=B1964_23340 PE=4 SV=1 +----GPEDMAKMGGMKFFPTAQDYVPEYLMLAS-PeSRVANGVIFETHGMLVPPPLGH----------------------- +>tr|A0A198ZL61|A0A198ZL61_ECOLX Dihydromonapterin reductase OS=Escherichia coli GN=A6I93_11755 PE=4 SV=1 +-DAEYRQQALNKSLMKTAPGEKEVIDLVDYLPV--ALSPDAVSHLMAVVICV---------------------------- +>tr|A0A191ZIG0|A0A191ZIG0_9GAMM Uncharacterized protein OS=Halothiobacillus sp. LS2 GN=A9404_09950 PE=4 SV=1 +-DTSYRKQRLAQNLLPFEPGAGVICHTIDFLMA--CPAIDATTIRVDNGHQG---------------------------- +>tr|A0A0X3T6X0|A0A0X3T6X0_9GAMM Short-chain dehydrogenase OS=Thiomicrospira sp. WB1 GN=AVO41_08085 PE=4 SV=1 +-SESLKQTRLAENAIPEPIGLAQIWQSVSYLMQ--SPAVTGTRLEVGQLQRE---------------------------- +>tr|A0A166GT79|A0A166GT79_9GAMM Short-chain dehydrogenase OS=Thalassolituus sp. HI0120 GN=A3759_06635 PE=4 SV=1 +-NEAYRNKVLSQSLIKHELGYQAIVEACDYLAN--SHAVCGNVMRVDGGRFV---------------------------- +>tr|A0A1A6KJF7|A0A1A6KJF7_9VIBR Dihydromonapterin reductase OS=Vibrio cyclitrophicus GN=A9265_00210 PE=4 SV=1 +-DEAYKTKALKKALIPAEAGFEEVIDGIKFVLA--SHYMTGRTLHLDGGRHL---------------------------- +>tr|W3WSH1|W3WSH1_9PEZI Uncharacterized protein OS=Pestalotiopsis fici W106-1 GN=PFICI_12192 PE=4 SV=1 +----YAVKAAKRCTAGRGGRPEEIAGPCIMLASKAGGYMNGGFLMIEGGRFMGASIH----------------------- +>tr|X8FKB4|X8FKB4_MYCUL Enoyl-(Acyl carrier ) reductase family protein OS=Mycobacterium ulcerans str. Harvey GN=I551_0601 PE=4 SV=1 +FTAQIRQTMREDRPLKREGTPEDIAEAALYFAGERSRYVTGPFFPWMVGRW----------------------------- +>tr|A0A0U1A6S9|A0A0U1A6S9_9MYCO Putative short chain dehydrogenase/reductase OS=Mycobacterium abscessus GN=sucB PE=4 SV=1 +-----ADMSGGTFTLTNIGVFGVDAGTPIINPGEAAILALGSVAKRPWVVNGELAVR----------------------- +>tr|A0A1N2N7G3|A0A1N2N7G3_9MYCO 3-ketoacyl-(Acyl-carrier-protein) reductase OS=Mycobacterium abscessus subsp. abscessus GN=SAMEA2275679_06194 PE=4 SV=1 +---QARELIGDLPENERDATGEDIARVISFLSDDNSAFINGSIIPVTGGKDILGKAY-RL-------------------- +>tr|A0A225UEE2|A0A225UEE2_9STRA Uncharacterized protein (Fragment) OS=Phytophthora megakarya GN=PHMEG_00039959 PE=4 SV=1 +-----FENVKEEVPTERLGEDSDMAGGAIFLASKASAWISGQVITCDGGMVGAAETG-----LISDIPRAKITINTMS-- +>tr|A0A0F4GQU9|A0A0F4GQU9_9PEZI Uncharacterized protein OS=Zymoseptoria brevis GN=TI39_contig350g00024 PE=3 SV=1 +--DKAMDTLLSGQPSGRVGTPEDFAGLVLFLSSMGAAHMTGNVLEVDGGSTLSGFRG--KVKRKADQKLCELL------- +>tr|A0A1C7MRI6|A0A1C7MRI6_GRIFR 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Grifola frondosa GN=fabG_1 PE=3 SV=1 +------------FPLEDRPRPTRPLVPYSFWRRPLPPLSQDIRSRSPADKASEVWT------------------------ +>tr|A0A072PQM6|A0A072PQM6_9EURO Uncharacterized protein OS=Exophiala aquamarina CBS 119918 GN=A1O9_00376 PE=4 SV=1 +-SPTSREAAVRAVPLQRFGLVKDVADATAFLFGDTGNFVNGTCLDVDGGAWRVQGAQ----------------------- +>tr|A0A0E9NQX5|A0A0E9NQX5_9ASCO Uncharacterized protein OS=Saitoella complicata NRRL Y-17804 GN=G7K_6340-t1 PE=4 SV=1 +-DDSRAKGILERIPAARWGTPEDFKGPVVFLASGASDYMCGEVMVVDGGWMGRQHSVTQLNILNMTKPTVLLLGKID--- +>tr|A0A0D5C4M9|A0A0D5C4M9_9ARCH Short-chain dehydrogenase/reductase SDR OS=Candidatus Nitrosopumilus adriaticus GN=NADRNF5_2106 PE=4 SV=1 +---ENVQEFVKSLPMKRLGEPDEIGNFVKAIIENKIKYLSGVTINFDGANS----------------------------- +>tr|H0YSD6|H0YSD6_TAEGU Uncharacterized protein OS=Taeniopygia guttata PE=4 SV=1 +MPQDLVDAFKP----------EYVAPLVVWLCHescaengslfeVGAGWIGKLRWERSLgaivrG------------------------------- +>tr|A0A1Q3NNU8|A0A1Q3NNU8_9GAMM Short-chain dehydrogenase OS=Acinetobacter sp. 38-8 GN=BGO19_14365 PE=4 SV=1 +--EQWLEGAAQSTMLHRLPTLSDVAETVTFLSSDYAHAMTATIVNMTAGATI---------------------------- +>tr|A0A1V0YU81|A0A1V0YU81_ACINO Short-chain dehydrogenase OS=Acinetobacter nosocomialis GN=B7L44_13430 PE=4 SV=1 +--GQWLEGAAQSTMLKRLPTLSQVAETVAFLASEHANSMTATVVNMTAGTII---------------------------- +>tr|A0A1W2FUY8|A0A1W2FUY8_KIBAR NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Kibdelosporangium aridum GN=SAMN05661093_09132 PE=4 +--PEWAGARqsItDASPLKRAATMADVGNVAAFVASDKGRSITSTQVNISVGACY---------------------------- +>tr|A0A0W7VL30|A0A0W7VL30_9HYPO Short chain dehydrogenase OS=Trichoderma gamsii GN=TGAM01_06743 PE=3 SV=1 +MHKEGLNAIKEAHPKTINVPISHVARYAAFLSEDGiGQSSNGGCVTITGNWP----------------------------- +>tr|T0KDK0|T0KDK0_COLGC Uncharacterized protein OS=Colletotrichum gloeosporioides (strain Cg-14) GN=CGLO_10392 PE=3 SV=1 +FHKEGLAVVVS-tfntvhgdpaKQGWNfgWSPLEQVAKTVLVLCSDGMNTINGALVPTDMGWT----------------------------- +>tr|A0A166TX75|A0A166TX75_9PEZI Short-chain dehydrogenase (Bacilysin biosynthesis oxidoreductase) OS=Colletotrichum tofieldiae GN=CT0861_07414 PE=3 SV=1 +FHQEGVAMVSS-tfntvqgdtaQRGWNfgWSPLNQVSKTVLSLCADGIHTINGALVPTDMGWT----------------------------- +>tr|G4MQV9|G4MQV9_MAGO7 Short chain dehydrogenase/oxidoreductase OS=Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) GN=MGG_04738 PE=3 SV= +IHQEAWARASK-vml--AADmkPISMETLAGYCVKLAEDNCSLFNGSCVTVDGGFS----------------------------- +>tr|A0A135UQF8|A0A135UQF8_9PEZI Short chain dehydrogenase OS=Colletotrichum nymphaeae SA-01 GN=CNYM01_12706 PE=3 SV=1 +VNQAGMAKVTAGMPEYKrgetGLDPAAVAKYCVFLTDKDiASSANGSCVVLNRNWP----------------------------- +>tr|A0A0F4Z1Z9|A0A0F4Z1Z9_TALEM Short chain dehydrogenase/oxidoreductase OS=Rasamsonia emersonii CBS 393.64 GN=T310_1565 PE=3 SV=1 +VNTEGFQLNER-lrg--GVGmqMVDLSDVAELALYVCTAEsAKIINGAIIPGDHGWT----------------------------- +>tr|U7Q340|U7Q340_SPOS1 Uncharacterized protein OS=Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) GN=HMPREF1624_02641 PE=4 SV=1 +-----QQFASVMkvn--EMSvgFSDTGRLGRLVLFLCGEDGQDINGAVIQVDRGWT----------------------------- +>tr|T0M5N1|T0M5N1_COLGC Uncharacterized protein OS=Colletotrichum gloeosporioides (strain Cg-14) GN=CGLO_00856 PE=3 SV=1 +VNQEGMMKTVAAQPEYKrgetGLDPAAVAKYCIFLTDKDiASSANGSCITFNKNWP----------------------------- +>tr|A0A0M9VTX0|A0A0M9VTX0_9HYPO Putative oxidoreductase OS=Escovopsis weberi GN=ESCO_001009 PE=4 SV=1 +--KERIDISLR----IYseesFVEEYAAAKHIASICEGDnGKMLNGSTINMCGNWP----------------------------- +>tr|W6Q838|W6Q838_PENRF Short-chain dehydrogenase/reductase SDR OS=Penicillium roqueforti (strain FM164) GN=PROQFM164_S02g002307 PE=3 SV=1 +MHMGGYEKMIG-vln--AIQapPVDVNEVAGFCVNMTYGKgAGQINGATIAIDNGWT----------------------------- +>tr|A0A0B7JJL3|A0A0B7JJL3_BIOOC Uncharacterized protein OS=Bionectria ochroleuca GN=BN869_000000904_1 PE=3 SV=1 +NDTEGLNLLMG-ncp--GLKdgsaMVPLDKMSSLIMFLSSDSASSLNGQILNADNGAV----------------------------- +>tr|W9VU69|W9VU69_9EURO Uncharacterized protein OS=Cladophialophora yegresii CBS 114405 GN=A1O7_06544 PE=4 SV=1 +PDKVGLDTVMP---TMAtqcgNCDPIDAANAIVFLATA--VGLNGSELRIDKGWS----------------------------- +>tr|A0A0B7KBQ5|A0A0B7KBQ5_BIOOC Uncharacterized protein OS=Bionectria ochroleuca GN=BN869_000010582_1 PE=3 SV=1 +-NMEVLGKMKG-flpGYPCIrgnsPPELTT--RIDIEQSFRD-----G--------------------------------------- +>tr|A0A0U0QU74|A0A0U0QU74_MYCTX Short chain dehydrogenase/reductase oxidoreductase OS=Mycobacterium tuberculosis GN=acr1_1 PE=3 SV=1 +-PADMPPPFRSLTPIPVhwvaaaVLDGVAXXXXCSWWvTRSRRGTATGWSACSRArySVA----------------------------- +>tr|A0A1F8R0W6|A0A1F8R0W6_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_58_14 GN=A2W36_05730 PE=3 SV=1 +-VKR---KTGRTTPAALrl--DAAEVAQAVLSIvRRPRRGLVIPWPMRFSVwlNVL----------------------------- +>tr|A0A1F9DAW1|A0A1F9DAW1_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RBG_16_47_11 GN=A2157_12185 PE=4 SV=1 +-DIG-------KVP--RrfIHWPEEVASRLVQAiRKDRQWDYSDYATRFSAwfGTL----------------------------- +>tr|A0A1Q5M6F0|A0A1Q5M6F0_9ACTN Uncharacterized protein OS=Streptomyces sp. CB02488 GN=AMK09_33735 PE=4 SV=1 +-TP----PTADQLAHA--LQPEDVAAMVAAIlQLPPRAYVPELMLCPSRl-------------------------------- +>tr|Q0CGD5|Q0CGD5_ASPTN Uncharacterized protein OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=ATEG_07257 PE=4 SV=1 +MTDEMRQARINQNLLKQEGTGWDVGYAILFLCSKEAKWITGLIMPVDGGTTAGKADR----------PALK--------- +>tr|Q9AQ15|Q9AQ15_BRASW Nitrogen fixation protein FixR OS=Bradyrhizobium sp. (strain WM9) GN=fixR PE=4 SV=1 +MSPDTEAHFVRKIPLWRVVHPRRSRRSFS-------SYVQMRQVMSLAPK------------------------------ +>tr|A0A071LVC6|A0A071LVC6_9ENTR Short-chain dehydrogenase OS=Mangrovibacter sp. MFB070 GN=DT73_10535 PE=4 SV=1 +IDKPIEEIGSKLHMKGRIINPQEIADAIYLLSLPEASAINGSTVMVDDGYASF--------------------------- +>tr|A0A0R1ZY10|A0A0R1ZY10_9LACO Short chain dehydrogenase reductase family oxidoreductase OS=Lactobacillus malefermentans DSM 5705 = KCTC 3548 GN=FD44_GL001891 +LGDFAAAAGGKLHMKGRILEPEEIANTIYLVSLPEASAINGTTVFADDGYTAF--------------------------- +>tr|A0A133KS62|A0A133KS62_BACCO Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Bacillus coagulans GN=HMPREF3213_01802 PE=4 SV=1 +IQAYKDagmtQKMTEQQMRKKLIRPEAIANAVYLLTLEEADVINGSVVMLDDGYASF--------------------------- +>tr|A0A090GQA7|A0A090GQA7_9RHIZ Uncharacterized protein OS=Mesorhizobium sp. ORS3359 GN=MPLA_680055 PE=4 SV=1 +-----KQAAVANIPIGEMALPAEVVELVAFVMRPSQASVNGATLDVDGGSYDEHRIG-KLG------------------- +>tr|A0A0B2VP39|A0A0B2VP39_TOXCA Dehydrogenase/reductase SDR family member 4 OS=Toxocara canis GN=DHRS4 PE=3 SV=1 +--EQELKKLCAMVPAGRIGQPRDCAGIVSFLLSDRAKYITGENTLVTGGVCDMWGVA------RRCAPSLK--------- +>tr|A0A0C5XD27|A0A0C5XD27_NOCSI 3-oxoacyl-[acyl-carrier protein] reductase OS=Nocardioides simplex GN=KR76_23185 PE=4 SV=1 +-RGAAEHALRVRHPSSAtYADVGAVVRAVEQLVAEPGLDRTGAVVDVSAGLAAT--------------------------- +>tr|A0A1A2Z161|A0A1A2Z161_9MYCO 3-ketoacyl-ACP reductase OS=Mycobacterium sp. E796 GN=A5706_04110 PE=4 SV=1 +--EAIVQRATRVNPIPEpWLEAEDVTRAVVHLVTDPGVLT-GVVMEIGLGSSAR--------------------------- +>tr|A0A0Q9R5S0|A0A0Q9R5S0_9ACTN Short-chain dehydrogenase OS=Nocardioides sp. Soil796 GN=ASH02_20205 PE=3 SV=1 +----------------DVYHPGNVSPLVGWLLTEG-CPENGSVWYAKGGEIRRFAGW-SYEWT----------------- +>tr|A0A0C1UQU9|A0A0C1UQU9_9ACTN Short-chain dehydrogenase OS=marine actinobacterium MedAcidi-G2A GN=MB53_05280 PE=4 SV=1 +----------------DDKSPDNVSPLVAWLVSSD-CDITGRTFEVTGGQLNVCDGW-QHGPV----------------- +>tr|A0A1V2KV17|A0A1V2KV17_9ACTN Short-chain dehydrogenase OS=Frankia sp. CcI49 GN=CcI49_04840 PE=4 SV=1 +----------------HAMDPSNSSPLVAWLASDEADHVTGQVIRSIEDRIIWMQGW-KERKV----------------- +>tr|A0A1X0D5T3|A0A1X0D5T3_9MYCO 3-oxoacyl-ACP reductase OS=Mycobacterium insubricum GN=BST26_15140 PE=4 SV=1 +----------------DPLSPEHVVELVRYLASPASDAVNAQLFVVYGPQVAMIAAP-TVAGR----------------- +>tr|A0A1S3ZTM8|A0A1S3ZTM8_TOBAC short-chain type dehydrogenase/reductase-like isoform X1 OS=Nicotiana tabacum GN=LOC107790362 PE=4 SV=1 +-TEEMIKRVIDECPNGRLGQTEDVAPVVGFLAVYDGCSSLNQIIRGFEFELW---------------------------- +>tr|A0A087NFH4|A0A087NFH4_9SPHN 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinC OS=Sphingobium sp. ba1 GN=IL54_3304 PE=4 SV=1 +SGKDVXXXX---RPQQDYPAATVVEYCSAVLTPKASS----SRLHQRCGRTPDR-------------------------- +>tr|A0A1A1Y0J4|A0A1A1Y0J4_9MYCO Short-chain dehydrogenase OS=Mycobacterium sp. ACS4331 GN=A5727_06365 PE=4 SV=1 +WL-DFGADYR-ESVGVAAATPMEQAYPLLFLCSDAAKVVTGITMVTDSGYLSAG-------------------------- +>tr|A0A1A3PMH2|A0A1A3PMH2_9MYCO Short-chain dehydrogenase OS=Mycobacterium sp. 1245111.1 GN=A5658_07820 PE=4 SV=1 +WL-DFGADYR-AKVGVAAATPMEQAYPLLFLCSEAASVVNGITLVTDSGYLSAG-------------------------- +>tr|A0A0W0FW88|A0A0W0FW88_9AGAR Putative short-chain dehydrogenase OS=Moniliophthora roreri GN=WG66_6919 PE=3 SV=1 +------------SPLKRPGRKEEIAAVDLYLSFCWRLVHEWYHYSS---------------------------------- +>tr|M7SPB5|M7SPB5_EUTLA Putative short-chain dehydrogenase protein OS=Eutypa lata (strain UCR-EL1) GN=UCREL1_6707 PE=3 SV=1 +------------FTTKRWNKPQEISSASIPCPT--LSVQ----------------------------------------- +>tr|R4XL16|R4XL16_TAPDE Uncharacterized protein OS=Taphrina deformans (strain PYCC 5710 / ATCC 11124 / CBS 356.35 / IMI 108563 / JCM 9778 / NBRC 8474) +TPTKAAAALQSMLEFpNRFGNADEFGHLVKSMIE--NTYVNGDVYNISGASRL-----GKL-------------------- +>tr|A0A0L0VV94|A0A0L0VV94_9BASI Uncharacterized protein OS=Puccinia striiformis f. sp. tritici PST-78 GN=PSTG_03874 PE=4 SV=1 +ISPAVRDNLLKTVEYpFRFGDPQEFSSLVMECIR--NTYLNGTSVLFSHIQLALLSrqSYGS--------------------- +>tr|A0A0Q5YBF4|A0A0Q5YBF4_9BRAD 3-hydroxy-2-methylbutyryl-CoA dehydrogenase OS=Bradyrhizobium sp. Leaf396 GN=ASG57_15880 PE=3 SV=1 +MPPKVSQSiVDRMILYpNRMGQPHEFASLVKHIAE--NAYLNATTISIDAGARMQP--R----------------------- +>tr|A0A087NA52|A0A087NA52_9SPHN 3-hydroxyacyl-CoA dehydrogenase OS=Sphingobium sp. ba1 GN=IL54_1418 PE=3 SV=1 +LPPDLVEELVDGAEFpKRAGRAEEFADAALFLIR--NPYINAEVLRLDGGARPPARtrWTAPA-------------------- +>tr|A0A1J4MF64|A0A1J4MF64_9CRYT Uncharacterized protein OS=Cryptosporidium ubiquitum GN=cubi_00844 PE=3 SV=1 +SMSEKISStLLKS-IPlGRFGVPNEFAETVINvGIK--SEYISGEIVYLDGAWRPPFItsGSIKR-------------------- +>tr|A0A1Z5T470|A0A1Z5T470_HORWE Uncharacterized protein OS=Hortaea werneckii EXF-2000 GN=BTJ68_10651 PE=3 SV=1 +MSDKVRKSLEGVFEFpKRPGQGKEFAMMVRSCVE--NTMLNGECVRLDGATRMPS-KM----------------------- +>tr|K2DDM2|K2DDM2_9ZZZZ Uncharacterized protein OS=groundwater metagenome GN=ACD_29C00372G0001 PE=4 SV=1 +-NPGLLEAVKHYAPLKKLIAPTEVAKYIIWLVNGGCHAVSGSVVDFDPGYTINRW------------------------- +>tr|L8WLX6|L8WLX6_THACA Uncharacterized protein OS=Thanatephorus cucumeris (strain AG1-IA) GN=AG1IA_08636 PE=4 SV=1 +------------IPFERSGKgksDIDMGGLALFLSSPAAYYVHGQIISIDGGFGAVNPTH--------VPPADGNIPTHHTP- +>tr|A0A1M5A568|A0A1M5A568_9BACL Uncharacterized protein OS=Seinonella peptonophila GN=SAMN05444392_1125 PE=4 SV=1 +--QEVLDQFTSTSPAKRIGTPEDVANLIVYLGSEANIFV----------------------------------------- +>tr|C1BDQ3|C1BDQ3_RHOOB Putative oxidoreductase OS=Rhodococcus opacus (strain B4) GN=ROP_pROB02-00930 PE=4 SV=1 +IEPGYHERHLAYTALGDLATPEDLGEGIAFFLEPQSDAVTGEVMRVAAGV------------------------------ +>tr|L7UK23|L7UK23_MYXSD NAD-dependent epimerase/dehydratase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_05527 PE=4 SV=1 +-KPELRASIASKSTFGRLITPEEIAHVLYFCAT--TATVNGAVLHANLGQ------------------------------ +>tr|F3KYM2|F3KYM2_9GAMM Oxidoreductase OS=gamma proteobacterium IMCC3088 GN=IMCC3088_1975 PE=4 SV=1 +-NTEVINAIGALNSFSRLVQPNEIASGVVFCHD--NPAINGSVFHLNLGQ------------------------------ +>tr|A0A085WC68|A0A085WC68_9DELT Oxidoreductase OS=Hyalangium minutum GN=DB31_1397 PE=4 SV=1 +-DAKTLEVLRSITGEGRLIEPQEIARVIAFAAD--HPVLNGTLIHANLGQ------------------------------ +>tr|A0A0A8E547|A0A0A8E547_9GAMM Uncharacterized protein OS=Allofrancisella guangzhouensis GN=SD28_03255 PE=4 SV=1 +-GGRHIDQAIENVAMKRIIDPKEIANFITYCVE--TPIVNGAVLHTNLGY------------------------------ +>tr|A0A1J4XB49|A0A1J4XB49_9PROT Uncharacterized protein OS=Proteobacteria bacterium CG1_02_64_396 GN=AUJ55_05285 PE=4 SV=1 +-IPEHMIPVEDVT------------AAIAYILdC--SPNTAPSE--IRLRP------------------------------ +>tr|A0A0D2NFS7|A0A0D2NFS7_9CHLO 2,5-dichloro-2,5-cyclohexadiene-1, 4-dioldehydrogenase OS=Monoraphidium neglectum GN=MNEG_3995 PE=4 SV=1 +------------NPIGRIARPEEVAEAVLWLCTS-ATYTTGSHLSLDGGADCGGQGVFVHTDVRDEAAVAALAEQIRSR- +>tr|Q0RLX8|Q0RLX8_FRAAA 3-hydroxyacyl-CoA dehydrogenase OS=Frankia alni (strain ACN14a) GN=FRAAL2831 PE=4 SV=1 +IPDRAAEALTKDAAFpKRMGRPDEYARLALAIVE--NPMLNGGTIRLDAGQRF---------------------------- +>tr|A0A0C9PYW6|A0A0C9PYW6_9HYME Scu_2 protein (Fragment) OS=Fopius arisanus GN=scu_2 PE=4 SV=1 +WSQEVKTRMINSGMTpKRIGHPTEIAHIIKCVIE--NHYINAENIRIDTGFRS---------------------------- +>tr|A0A0Q9W6J7|A0A0Q9W6J7_9BACI Uncharacterized protein OS=Bacillus sp. Soil768D1 GN=ASG99_13965 PE=4 SV=1 +LKDKGLTDLYKNCQMrKEFIEPEDIAGMVCllAMEE--ANVVNGSVVMLDDGLTG---------------------------- +>tr|A0A1B3PIA2|A0A1B3PIA2_9BURK Short chain dehydrogenase family protein OS=Acidovorax sp. RAC01 GN=BSY15_3288 PE=3 SV=1 +MPTKVSQnIIDNVILFpHRMGQAQEFGGLVRHVVE--NAYLNATTISLDAGVRC---------------------------- +>tr|A0A1E4HRR1|A0A1E4HRR1_9PROT 3-hydroxy-2-methylbutyryl-CoA dehydrogenase (Fragment) OS=Rhodospirillales bacterium SCN 65-16 GN=ABS83_01865 PE=3 SV=1 +APENVKAALAASVPFpKRLGRPEEYAQVAQTMIT--CGYFNGEDVRIDGAIRM---------------------------- +>tr|A0A1X0I808|A0A1X0I808_9MYCO Uncharacterized protein OS=Mycobacterium paraseoulense GN=BST39_17335 PE=4 SV=1 +----LVNAMQTALPDLLLIEPKDVSNAVLFLISEAGRSFTGSVLKVDAGM------------------------------ +>tr|T0HDE8|T0HDE8_9SPHN Uncharacterized protein OS=Novosphingobium lindaniclasticum LE124 GN=L284_13070 PE=4 SV=1 +IPAEAVNHLADQTVANRYLSAEEVAQAFAFLCSDRASGISGDLHHVNGGGYFSLQY------------------------ +>tr|M2N8V6|M2N8V6_BAUCO Uncharacterized protein OS=Baudoinia compniacensis (strain UAMH 10762) GN=BAUCODRAFT_123932 PE=4 SV=1 +YSPEFVQKWQADNPLQRVPEPEECADIFVALAK--NLSMTGQQIPIECGWLLTHSH------------------------ +>tr|A0A094I3B7|A0A094I3B7_9PEZI Uncharacterized protein OS=Pseudogymnoascus sp. VKM F-4519 (FW-2642) GN=V501_02963 PE=4 SV=1 +YPEATIKFMEERAYLKKVTDLEDCAQSFIDTAR--NSSMTGQKIVVGGRAVSWKEW------------------------ +>tr|N1PLT5|N1PLT5_DOTSN Uncharacterized protein OS=Dothistroma septosporum (strain NZE10 / CBS 128990) GN=DOTSEDRAFT_130457 PE=4 SV=1 +YGEERINGLKNAAALKKETEMGDCAQMFVDIAK--NTSMTGQAVHVGQSVSIWANG------------------------ +>tr|U4L2C8|U4L2C8_PYROM Similar to Granaticin polyketide synthase putative ketoacyl reductase 2 acc. no. P16543 OS=Pyronema omphalodes (strain CBS 1003 +FGEEKIKKATEKTKLGTLGSLEDCAEGYVYLAK--ADTVTGASLKIDGGAHEH--------------------------- +>tr|G0RWM3|G0RWM3_HYPJQ Predicted protein OS=Hypocrea jecorina (strain QM6a) GN=TRIREDRAFT_124136 PE=4 SV=1 +FPEEVIEGYKRISTLRDVVALDDCADAFVSLAK--NSAMTGQQIVVVDQSLAVIPK------------------------ +>tr|A1CE83|A1CE83_ASPCL NADP(+)-dependent dehydrogenase, putative OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 +FPPEKLQGFKNKAVLGKLPEVEDAAEAYVMLAK--NPSMTGQSIQIGKHSQASFYS------------------------ +>tr|B8LU00|B8LU00_TALSN Short chain dehydrogenase, putative OS=Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006) GN=TSTA_07 +FSEEYVENHINQTALKRVAELDDTADLYISLAK--NASITGQSLAVGESHFVHLFE------------------------ +>tr|W9X3T1|W9X3T1_9EURO 3-oxoacyl-[acyl-carrier protein] reductase OS=Cladophialophora psammophila CBS 110553 GN=A1O5_05399 PE=4 SV=1 +YSDERIQAVKNAAALKQETIVQMPISRLRKTRR--SQ--ASRLSLVSSGSWVLLAK------------------------ +>tr|G1XQ71|G1XQ71_ARTOA Uncharacterized protein OS=Arthrobotrys oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491) GN=AOL_s00188g82 PE=4 SV=1 +FPQEAKDKYLGMTQTKKHVEAVDVADAFVFISQ--NVAMTGQKIVIDGGVVIQP-------------------------- +>tr|C4Y271|C4Y271_CLAL4 Uncharacterized protein OS=Clavispora lusitaniae (strain ATCC 42720) GN=CLUG_01212 PE=4 SV=1 +FPQEKVQQTVEASPIKKLADIDETAAQFILLCK--LATSTGTIVGIDGGIYV---------------------------- +>tr|D5GPB4|D5GPB4_TUBMM Uncharacterized protein OS=Tuber melanosporum (strain Mel28) GN=GSTUM_00011788001 PE=4 SV=1 +FPEEAIERTKERSKLKVAPTVEECADAFVLMAK--SSSMTSSTLKIDGGLYT---------------------------- +>tr|A3LSQ5|A3LSQ5_PICST Granaticin polyketide synthase putative ketoacyl reductase 2 OS=Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 1 +FPQDRIDKSKQISPINAIPDVEETAAQFVLLSK--LATSTGSIVAQDAGISL---------------------------- +>tr|A0A1A5ZTG0|A0A1A5ZTG0_9TREE Uncharacterized protein OS=Cryptococcus dejecticola CBS 10117 GN=I303_08432 PE=4 SV=1 +FTDAQIAAVKRINSLHQVTSIADVASAYVMLAQ--NGSMTGQTIEVSSGFRLGRD------------------------- +>tr|A0A1L9UGC5|A0A1L9UGC5_9EURO Uncharacterized protein OS=Aspergillus brasiliensis CBS 101740 GN=ASPBRDRAFT_31608 PE=4 SV=1 +FPAEAIERWTAKTALGKVPELEDTAQAYVMLAQ--NSSITGQEIQIAELTLQIPAS------------------------ +>tr|A0A1L9RMK3|A0A1L9RMK3_ASPWE Uncharacterized protein OS=Aspergillus wentii DTO 134E9 GN=ASPWEDRAFT_134832 PE=4 SV=1 +YGTDAIAKMKNGSILKQETLLEDCAEAFVSLSK--NTSTTGEHVLVDSGFLVGTST------------------------ +>tr|A0A1L7WN77|A0A1L7WN77_9HELO Related to cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase OS=Phialocephala subalpina GN=PAC_04112 PE=4 SV=1 +FTEEQRQGFKEMAKLKRITTPEEIAMTFVFAAK--NSGMTGERIRVDSGMVVV--------------------------- +>tr|A0A1U7LU95|A0A1U7LU95_9ASCO Granaticin polyketide synthase putative ketoacyl reductase 2 OS=Neolecta irregularis DAH-3 GN=NEOLI_002385 PE=4 SV=1 +FGEEKLKKHVASNALQKMTDLDDVAALYTMLAA--NESITGENFNVASTVL----------------------------- +>tr|A0A232LV83|A0A232LV83_9EURO Uncharacterized protein OS=Elaphomyces granulatus GN=Egran_04184 PE=4 SV=1 +FGQTQIEEWPDKLVLKRIVDLDDCAALYPAIAK--NSSMTGQSIQVDSGAIIR--------------------------- +>tr|A0A1Y1Y4L8|A0A1Y1Y4L8_9PLEO Short chain dehydrogenase/reductase OS=Clohesyomyces aquaticus GN=BCR34DRAFT_248418 PE=4 SV=1 +YPQETIDFVINKATLHHETDLQDTADVFVMLAR--NTSMTGAKVQIDAGLNIQG-------------------------- +>tr|A0A1Y2FGH8|A0A1Y2FGH8_9ASCO Uncharacterized protein OS=Protomyces lactucaedebilis GN=BCR37DRAFT_346765 PE=4 SV=1 +FDRQKMDWVTANTPTGAIATLEDCADAVHLLCA--NKSISGQTIVLDGGFTLR--------------------------- +>tr|A0A0N8P2E4|A0A0N8P2E4_9PROT Uncharacterized protein OS=SAR11 cluster bacterium PRT-SC02 GN=JI56_02095 PE=4 SV=1 +LNKRLRKKILNKIPSKKTGDVKNIFNAIQFLVD--SDYVNGSLIKIDGGY------------------------------ +>tr|A0A1Q5SKX7|A0A1Q5SKX7_9BRAD Uncharacterized protein OS=Bradyrhizobium sp. NAS80.1 GN=AC629_08705 PE=4 SV=1 +LDEEGRRRIAGRGTLRRLPEADDVASMVEYLLGEGGRNPTGTVLTVDAGNTA---------------------------- +>tr|C5FK54|C5FK54_ARTOC 3-oxoacyl-[acyl-carrier-protein] reductase OS=Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) GN=MCYG_02895 PE=4 SV=1 +LGEQFRNDTMQSIPLRRFGTIEEVADAAVFVVT--NQYANNCVLNLDGGLSA---------------------------- +>tr|A0A0C3BVY9|A0A0C3BVY9_HEBCY Uncharacterized protein OS=Hebeloma cylindrosporum h7 GN=M413DRAFT_79321 PE=4 SV=1 +Fv-----TEATCCGEYpRRPGRPEEFSHLVQSLFE--NEMMNGAVVRQDAA------------------------------- +>tr|A0A1X3HFG2|A0A1X3HFG2_9BRAD 3-hydroxyacyl-CoA dehydrogenase (Fragment) OS=Bradyrhizobium canariense GN=BSZ18_00155 PE=4 SV=1 +LNEEARASLGAQVPHpARLGDASEYGNLAVHIVE--NPM------------------------------------------ +>tr|F8TTM4|F8TTM4_9BACT Short-chain dehydrogenase (Fragment) OS=uncultured Acidobacteria bacterium C5 PE=4 SV=1 +FGEEFIEFASKLNLERQFVGVDEVASAIFGLCSGLMDGVSGQVIMVDRGGTFS--------------------------- +>tr|A0A077W3Z7|A0A077W3Z7_SALTM Uncharacterized oxidoreductase yghA OS=Salmonella typhimurium GN=yghA_2 PE=4 SV=1 +QPQEKVEKFGANAPLGRPGQPVEIAPLCHPGRSGEQLYVWsGLVF------------------------------------ +>tr|A0A1F3VAI5|A0A1F3VAI5_9PROT Uncharacterized protein OS=Bdellovibrionales bacterium RIFOXYC1_FULL_39_130 GN=A2404_16800 PE=4 SV=1 +LSKQLKYDYLKHCSLRRYGKAIEVANMAVWFLEE-NSYITGKTIVLDGG------------------------------- +>tr|A0A1T1HT40|A0A1T1HT40_9PSED 3-oxoacyl-ACP reductase OS=Pseudomonas sp. MF4836 GN=MF4836_23300 PE=4 SV=1 +IPLLIREAGRRMNSLSQGGQAVDVAQTIAWLAHPASGGINGQVVRVCGQSLLG--------------------------- +>tr|A0A176I6L8|A0A176I6L8_9GAMM 3-oxoacyl-ACP reductase (Fragment) OS=Oleibacter sp. HI0075 GN=fabG PE=4 SV=1 +IPFMTREVGRRLNSLSQGGKPVDVAETIAFFGNPASNGVSGNVVRVCGQSLVG--------------------------- diff --git a/esm/source/examples/data/UniRef50_UPI0003674933.a3m b/esm/source/examples/data/UniRef50_UPI0003674933.a3m new file mode 100644 index 0000000000000000000000000000000000000000..5244347038c1caed73ba2d10cf9a3582da9a7c8d --- /dev/null +++ b/esm/source/examples/data/UniRef50_UPI0003674933.a3m @@ -0,0 +1,2130 @@ +>UniRef50_UPI0003674933 +MKKKEDILNLEHTLLPWMGRTMKVLDYFIGDFLNLKGIELTKVQWILLKKLNEQNGQPQQNLAFLTNRDKASLARLITTMEKKKLVERIPSKIDGRINHIFITKHGCEILQKSAPVIEKVVGCIQEGISPEEIETVIKVMQKVNNNINRASN +>tr|A0A1J5IWR0|A0A1J5IWR0_9PROT Uncharacterized protein OS=Zetaproteobacteria bacterium CG2_30_59_37 GN=AUK36_09885 PE=4 SV=1 +MENPQqqPVSGELGAIMPLIGFMSSHVRFHISRICSDAGHPLTPEEAGTLMIIRHFKGLPQTRLAVILGKDKAAVTRLMNALVKSGLVGRIPDEQDRRVVRAQITGLGEQAFIKLWPELTKLSDEALKDIPKQDLEQLSNVLRLINANLAA--- +>tr|K7SNK0|K7SNK0_9HELI Uncharacterized protein OS=Candidatus Sulfuricurvum sp. RIFRC-1 GN=B649_08095 PE=4 SV=1 +-----------------TNLSAMAARNYLTRQLSLHGIDMTIEQFKVMVVLWKEGTSTQQNIADFVGKDKTSITRLIAGLEKRSLIGRATDENDKRCNLVTLTPQGIALEKPTMEVLQQANESLQKHFNPEELAITLRVLKQMCLSLN---- +>tr|G2H9E7|G2H9E7_9DELT MarR family protein OS=Desulfovibrio sp. A2 GN=DA2_2506 PE=4 SV=1 +-----------------TFTTSRLMAAFLRRRMAQAGIDLTGEQWGVMVFVWNRGAIGQDELAHALCMDKTGMSRLLATMEGKGLVTRNPDPADARRRAVRATKQGDALKERCRAVAEEALVLLLKDVSPQDHATCMRVLATVKETLR---- +>tr|A0A238YWN1|A0A238YWN1_9DELT DNA-binding transcriptional regulator, MarR family OS=Desulfovibrio mexicanus GN=SAMN04488503_1042 PE=4 SV=1 +-----------------ATQFSKAVLRRINQEFAAGGHAVTGEQWTALVHIWDAEGLTQQELGQRLIKDKTTIARLVAGLERQGYVRRKPGASDRRERLLALSERGRADMPVLAALVQGVLDQACAGIDAHELSLCRRVLARARQNLV---- +>tr|A0A212K2M8|A0A212K2M8_9BACT Putative MarR family transcriptional regulator OS=uncultured Dysgonomonas sp. GN=KL86DYS1_31248 PE=4 SV=1 +-----------------IASVAAQLRRLAFRLISEKGLDITPEQWVILYYLWLDDGLSLSELTKKSKKDFANTTRIIDKLCTAKYVVKQKSITDSRSYNIFLLPRAESIRQEVITCWTEATAIFTNGLSEDEINIFLKLLAKVENNLS---- +>tr|K1Z1N7|K1Z1N7_9ZZZZ Transcriptional regulator, MarR family OS=groundwater metagenome GN=ACD_77C00282G0001 PE=4 SV=1 +----------------LVSKTSQKFKLELNRKLKKSGLDVSSDQWTVLMYLSDNNGPSQTDLAQKLYKDRANLTRILDLMEKNQLVERQRSSIDRREYNVFITEKGMSLIPQLKLIGDSVMEKALKGANAEEIIGIKHFLNKLFINLDN--- +>tr|A0A161LG42|A0A161LG42_9BACT MarR family transcriptional regulator OS=Paludibacter jiangxiensis GN=PJIAN_4298 PE=4 SV=1 +----------------LSGRVGDKIKRPFYKAFARECIAISSEQYAILACLVKQNMVTQQTLCGLTKKDKPNVTRLIDRLENKSLVQRIADAEDKRKKRICITEQGMLVYEKVNHIVSDMVSHAMKNIDEGQLVVFQDVLRHMMHNLSM--- +>tr|A0A1N7MZJ4|A0A1N7MZJ4_9BACI Transcriptional regulator, MarR family OS=Salimicrobium salexigens GN=SAMN05421758_1105 PE=4 SV=1 +--------------------ASRVMNARLNENFKKIGHTLTYEQWQIMSRLYGKEGQTQRMLAVSIERDEAGTSRLLGRMEKAGYIYRYVNPEDKRRNYIYPTEWARQEEEKLNRTALDTIDEACAGMTEEEKRSGQLFLEKIRNNLGSS-- +>tr|A0A1Y5GH82|A0A1Y5GH82_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium 45_16_T64 GN=A9Q99_25160 PE=4 SV=1 +--------------------ISRYVNQWLERALSSTDT--SLQEFKIIGLLMGSDDITQKTLAEYLSVRPATLSVAITNLENKGYIQRVTSQEDKRVNYIRLTKNVDMEQG--VDILHGLEDKATKGITKKDLAVTQRVLNQIAQNLKED-- +>tr|A0A117T141|A0A117T141_9BACL Uncharacterized protein OS=Paenibacillus sp. DMB5 GN=AWJ19_10345 PE=4 SV=1 +----------SEKLSVIFYRVNRNYQYLMALH--LKPFQITPEQWNVLKYLQEQDGLTPKDLTYMADKDKTTITRIIETLVERGTVTKEMNPDDRRSFRIFLTDTGRELIREVQPIPDLVNKKVCRELSVEQIIGLKEMLYLMQTQI----- +>tr|Q7MS26|Q7MS26_WOLSU Uncharacterized protein OS=Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) GN=WS0847 P +----------KNSPGFWIGRIHHKLKNRMNQR--LKPYDLTAEQRLILLRLFEFGEMTQQQLCQKTFTEPSNITLTLRRMESHGYVRKKPHPKDKRASLIEATPKALSIQNELERIGLEITDSLLLEVDPSEKETLLRVLQAMYQKM----- +>tr|A0A010YSS6|A0A010YSS6_9BACL Transcriptional regulator OS=Saccharibacillus sacchari DSM 19268 GN=SacsacDRAFT_0185 PE=4 SV=1 +----------QDSIGFQLGVIYRKVSNRLAAN--LKDYDLTPEQWSVMCCICFKEGMNQKEIAERTVKDQPTVTRILNVLHRKGLIMRSSDRADRRAYLIYPTEKGRQVTEETSVIERHHNAAMIEDFSPEQLELLAEAFRKIERNA----- +>tr|M1PSV6|M1PSV6_DESSD Transcriptional regulator OS=Desulfocapsa sulfexigens (strain DSM 10523 / SB164P1) GN=UWK_02870 PE=4 SV=1 +----------RKPIGRLLYMTAQAMTLHAEKV--LKPYDMTVEQLHILKNMDENTALSHQELSKIVQKSAANVTRILDRLERKNYIRREKNPKDRRSILVLITAQGRDLVAEVSLVLEAFTKQLTRGITIEEQDLFTQILCTMQGNL----- +>tr|A0A0S2I4U6|A0A0S2I4U6_9BACT Salmolysin OS=bacterium L21-Spi-D4 GN=slyA PE=4 SV=1 +----------KKSLGLLSLAISKGLGNRLEQK--LKAqkINITADQWSVLSMLRHEGESSQKNISDVFGYDKVRVLRIVRNLEDRGILNKRVCSHDKRTRIVSLTSEGMSLYAKIHPIAEATINEATKSLSNREVRLYTEISQKIIMHL----- +>tr|M8DDE2|M8DDE2_9BACL MarR family transcriptional regulator OS=Brevibacillus borstelensis AK1 GN=I532_01995 PE=4 SV=1 +----------RDSLGHNLHRVGQLIREETAKA--L--gpFGITPEQWQLLVATAQTDGLTPSELGKRTLRDKTTISRILPGLLKKGWLKTEPHSQDARSYIVKMAPDKVKVIEETLEAVRDHFTQSVFaPFSKAEQDMFLSMVVRLRDHL----- +>tr|A0A173XS91|A0A173XS91_9FIRM Salmolysin OS=Mitsuokella jalaludinii GN=slyA_2 PE=4 SV=1 +----------DNTIGYMISRVARKIHYAVDEV--FKAYGITVEQWVALKTIAEYEPLCQKALAEKIEKNQNTVKALVTHLDDKGFIDRTPNPDDMRHMMLRTTERGRALVARLTELDEHKNFDFLGALSEAEQEDLRRMLRKIEARL----- +>tr|A0A1C0AUD3|A0A1C0AUD3_9PROT HTH-type transcriptional regulator MhqR OS=Arcobacter thereius GN=mhqR_2 PE=4 SV=1 +----------NKSLGFILNRTALASKNAFNQE--IKDYEISPEQWSVVYRVIKEPGISQKLVSDSTYKNQGNLTRMIDKLEKSDFLIKKQNSENRREIQLFPTKKAIDLSKPIIEHSTQHNNNMLDTFSTSEKEQLFNLLNKVYNNL----- +>tr|A0A1R0X1Z1|A0A1R0X1Z1_9BACL Uncharacterized protein OS=Paenibacillus odorifer GN=BJP51_25985 PE=4 SV=1 +----------MDNPGQLLIRVSLEMKKSLTKK--LLLYNVTAPQWAVLKDISIhLEGTTPAMIAERTYSDRPTITGILERLKAKGLLDIRDNPNDKRSNLVFITDSGMIIKSQIEVLSDEIMDNALKNISEQEMSTFMNVLKTIYLNI----- +>tr|A0A1Q7WIB2|A0A1Q7WIB2_9ACTN Uncharacterized protein OS=Actinobacteria bacterium 13_1_20CM_3_68_10 GN=AUG43_03210 PE=4 SV=1 +----------EQQVSALVFHLGRELRTALDRR--LTShgLTSQQAALILLSRLLH--EPNPNKMAERLGTDTAGMTRLIDRLEKKGLIFRKTSPEDRRSIVIVLGPKSKHMLPRLIPEFRHVEDSVLDGFR----------------------- +>tr|A0A1T5BLS8|A0A1T5BLS8_9PROT Transcriptional regulator, MarR family OS=Arcobacter marinus GN=SAMN06295997_11474 PE=4 SV=1 +----------ENSLGFKISQTANRLNYQFVQL--LTQYDIAPEQRATLEIISNDNEVSQTKIASILGKNKTTICRSLNSLEKKGLIIRDCQIKDKRVNIIKLTQKGKDVLQASQNCVIEFRKKINSNLTKEEINKLFELLNKVSNTI----- +>tr|A0A1F3KA74|A0A1F3KA74_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWF2_33_38 GN=A2W98_10055 PE=4 SV=1 +-----------------VGRMMHMmFRVLKKRTGEq-ADVKLTIEQFGLLHAIsMKEEDVIQKDMAEMMGKDKSAILRIIDTLEEKELVRRVVDTNDRRKNFLMVTKKGEKVLEQCLKIEFELMEELQQGLSKSDLDTFYKVINHIRSRAEK--- +>tr|K4KI77|K4KI77_SIMAS MarR family transcriptional regulator OS=Simiduia agarivorans (strain DSM 21679 / JCM 13881 / BCRC 17597 / SA1) GN=M5M_02145 PE +--------HLHNSFAFWIGRLAQQMQEQFNRDL--KEHDISWHQWALLNVMLHGVAKTPAQAADAIGADRSTVTRMLDRLEKRGLTTREHDGLDRRVVKIALTKDAMALMTQLNQLAQAHQTQFLSELPSTEYRSLRGSLVKMLRAGGV--- +>tr|A0A150AFH7|A0A150AFH7_9BACT Uncharacterized protein OS=Flammeovirga sp. SJP92 GN=AVL50_22905 PE=4 SV=1 +--------EKRRRLTKIIAQVSRLGNYTLGRAFEREGLPISREQWDVLVMLWDKDGRAQQEFATFLLKNRASITSLIDNMEKNNLVTRVPNPNDKRSKLIYLTRKARDLKEQVVGIAQDAILSITKGIPLEDVEHAADLLTKCLENIVE--- +>tr|G4RFE5|G4RFE5_PELHB Transcriptional regulator, MarR family OS=Pelagibacterium halotolerans (strain DSM 22347 / JCM 15775 / CGMCC 1.7692 / B2) GN=KK +--------DYQAATPHWVNRLSFLIRAEVQQRFKAAGYAITAEEWAMLMLLWPNAPQSMGQLAAVSLRDRTTVTRLVDSMVAKGLLERTPAPNDRRSVLVDLGPKGRALEAPLTAIVGDFIAQATKGLSADEIARANAVLQKMTANILG--- +>tr|A0A1J4Y9F8|A0A1J4Y9F8_9PROT MarR family transcriptional regulator OS=Zetaproteobacteria bacterium CG1_02_55_237 GN=AUJ58_09410 PE=4 SV=1 +--------QLEQAIGLNVNRTAFLMTEEIARRFARHDYPLSAQDFGILFRLFKQGPRTQVEIAALMMRDKTTITRRIDGLVKKQLVERMPDPDDRRYFRVTLTEQGHRALEVMIPLVRDFQQEVLSDIPDEEKAITIRTLQQISEKLIK--- +>tr|A0A1R0WV32|A0A1R0WV32_9BACL MarR family transcriptional regulator OS=Paenibacillus odorifer GN=BSK60_09985 PE=4 SV=1 +----------------------------------FRPYNMTRSQWIAMYYIYTSESITQRELADKMSIKEPSVVRLLQKLESEGFLHRSGTHADKRVKQLELSDKGVQIYLDLLPVAEKFKDDTITNISEQDLQTFKNVLGVMVENAS---- +>tr|F2IDX4|F2IDX4_FLUTR Regulatory protein MarR OS=Fluviicola taffensis (strain DSM 16823 / NCIMB 13979 / RW262) GN=Fluta_2531 PE=4 SV=1 +---------------YKIDRAIRTYRQFAQARLRSLGHQITIDQWLVIKCLIENPKIQQNEISEQVFKDAASVNRMINLLVESKYLKRKINKLDRRKMDILVTQKALDAIDAMDEVIPNNRSHALTGLTQEEMQIATKVMTQIATNCK---- +>tr|A0A136PBY2|A0A136PBY2_9BACT DNA-binding transcriptional repressor MarR OS=Chlorobi bacterium OLB5 GN=UZ05_CHB002000392 PE=4 SV=1 +---------------SNLEFTLKSYKKHLSSIFDKSSILITPDQWQVLDIIVNHKDIKYSEIAVISGKDIASVNRIIDLLNQKGYVSRQTDPNNRRRVILGVSNDGVKIHKRAGELINIESKKLLDGFKEKRIIKAGKDV------------ +>tr|A0A1N7ICK1|A0A1N7ICK1_9FLAO DNA-binding transcriptional regulator, MarR family OS=Chryseobacterium joostei GN=SAMN05421768_104115 PE=4 SV=1 +---------------YNIDKAIRSYRNYAQRQLKAHGFTITIDQWLIIKAILENPGITQNEIGDLVFKDNASVTRIIDLMVKSEYIIRHIHPDDRRKTNLEVTDSGKKVIKEVQNIVEKNRKAALKGVSKDELEVMYSALLTISENCL---- +>tr|A0A1D7V107|A0A1D7V107_9LEPT Uncharacterized protein OS=Leptospira alstonii GN=A0128_17685 PE=4 SV=1 +---------VKDAYGFLIVRSNRLFRLHFQRLCQRNDIDISQEQWFLLNKIAHSEGLTQGDLTDDLFGDKPNISRMVEKMEQKGWIRRVNDSTDNRILRLHLTKKGSATHERMVSIVGEERNKIYAGLSSKDFKDFERIIGILEKNL----- +>tr|A0A098F3P9|A0A098F3P9_9BACI MarR family transcriptional regulator OS=Bacillus sp. B-jedd GN=BN1002_03714 PE=4 SV=1 +----------NRHVGLLIRNADLSLANYIKK--QLEPFNLAPEQNLIMMMLWEKDGVSPNELVSCLKKDKGNIARMVASLEKKGYIKRVADPGDKRTFKIHLTEEGRRLECSVEPILQEATRTVTNGLSPEQVSQLQEMLTKIIDNLSG--- +>tr|A0A0Q4HCR7|A0A0Q4HCR7_9MICO Uncharacterized protein OS=Agromyces sp. Leaf222 GN=ASE68_09805 PE=4 SV=1 +----------SIEVGILLNQVHSVATERLNT--ALQPMNLTSRHAAVMFLIRD-GVETQRDLVRRLNTDKTGMVRMVDDLDRLGYVSRTPSTSDRRVTILTLTSAGEHALREAQQHTRRVADDVFRSVGSTELMELRSILSGVMGREIP--- +>tr|F8E9W7|F8E9W7_FLESM Transcriptional regulator, MarR family OS=Flexistipes sinusarabici (strain DSM 4947 / MAS 10) GN=Flexsi_1736 PE=4 SV=1 +----------EKDISMTLAKVFFGMKKIFTK--LWSEYDITPEQVGILTILWDEDGLSQHDIAKRSIKDAPSTARLISRLIDRGFVKCVTDRQDRRCTNVFLTEKGRKLEEPAKSIMPEYNSMIYNGISNKEKQELLGILQKMYNNIEN--- +>tr|A0A174AVI2|A0A174AVI2_SARVE Salmolysin OS=Sarcina ventriculi GN=slyA PE=4 SV=1 +----------RIKLSKWADILSNNFQAYVNL--KLKPYDLKFAEFICLLNLYENDGSHQDFIIKRKYTDKSAITRTLQSLEKKGFVRREKSEEDKRINCVYLTEKALDYKEELDKIIDEWEEFLNDCIPRDEYNKIATALEDITIKVLT--- +>tr|F8ED64|F8ED64_RUNSL Transcriptional regulator, MarR family OS=Runella slithyformis (strain ATCC 29530 / DSM 19594 / LMG 11500 / NCIMB 11436 / LSU 4 +----------EKNIGRYIGRLNYLGLKRMNELLTEAGANITADQFRLLTHLWKQDGIPQNQLALHLGRDRAGVTRMVDILENQHIITRIADTNDRRINLIYLTKTGKELETKAAECAQKYLNEMMEDFSEDEKIQFSSLLQRAVTSLKK--- +>tr|A0A0C2SYG4|A0A0C2SYG4_BACPU Uncharacterized protein OS=Bacillus pumilus GN=B4127_2035 PE=4 SV=1 +----------HDLIGYLVHRTDVKMTNYFTN--RLKPYGVTPEQWSIISILSREKGSTQKELAEGIDKNQTTVVRMIQSMERKGLVKKIYNEQDRRSHHLFLTEKGDEIKKAILPVVMDAHRTVTHQLSDEEIQQLKLLLNKLFHSDYP--- +>tr|A0A1M6WW48|A0A1M6WW48_9FIRM DNA-binding transcriptional regulator, MarR family OS=Anaerocolumna jejuensis DSM 15929 GN=SAMN02745136_03787 PE=4 SV=1 +----------TKLIGYKIIKGEVLIKRKILNAFIEKGYMITFEQWIVLNVLYAEPGIIQSEIAQRTYKDKTNVTRILDVLAKNGYIIREANDKDRRIACVYLTDAAKKMFADIIPYIEEINEHFCNGISEEELALFDDIFGRLCKNAE---- +>tr|A0A1V9JTI8|A0A1V9JTI8_VIBSP MarR family transcriptional regulator OS=Vibrio splendidus GN=BK411_02235 PE=4 SV=1 +----------QKSFGWMINVIANKSTKDFDT--ELKEHGLSIALWPTMMCLWEEEGVTQRDIAAKSKVENSTTTRTLDKLEKLELVERRADPNSRRSFRIYLTEKGKALEEQLVPIPVRLNKELMNELDAEEQQQMLKLLQKVVAAI----- +>tr|M1WNE2|M1WNE2_PSEP2 Putative Transcriptional regulator, marR family OS=Pseudodesulfovibrio piezophilus (strain DSM 21447 / JCM 15486 / C1TLV30) GN= +----------TETLGFQLYLSARLLKARFRRALVDAGCELTPEQHAVLRKLWECEGVHLNELAQSIFKDRHNTTRIVKNLEKKGLVYKLPHEKDARLTRCFLTEEGKQLIPGLVDIATSHLSEVFKDIDEEDRVVMQRVLGQLVMTLEN--- +>tr|A0A0M2H6V3|A0A0M2H6V3_9MICO DNA-binding transcriptional repressor MarR OS=Microbacterium trichothecenolyticum GN=RS82_04002 PE=4 SV=1 +----------------------------------LADRAARRCARThVLWLVFHEGPRTQAELATGLGVTPRNVTTLVDGLEATGFARREPHPHDRRAVLVTLTDRGEVAMRAMDAEHTRLGAQLIDGLDDATAQATLRGLNHVLDRLSRL-- +>tr|A0A1E3GA93|A0A1E3GA93_9GAMM MarR family transcriptional regulator OS=Piscirickettsia sp. Y2 GN=BGC07_07015 PE=4 SV=1 +----------------------------------S--qgLGIGPTERRALYAIYQNPGLTQVQLAEFLDIEPQGLTRILDHFVDLNWLRKEIAPKDRRARCLYLTSASNPIIEKIRAIGDEFRPQSLENISNNELENFINTIKKMKENLATI-- +>tr|A0A1B6ZE56|A0A1B6ZE56_9SPHN Uncharacterized protein OS=Sphingomonadales bacterium EhC05 GN=A8B75_06855 PE=4 SV=1 +----------------------------------MQQLGLTRAQWQVLVRVLIIGSPTQTELADSLDIGRASAGNLIRQLEEKGYIKRYDDEDDQRVRRVIASKRAIASSEKMTQIGSDVASRAFAGIAEDELAVAAQVLGSIRRNVANL-- +>tr|A0A1D2SSV6|A0A1D2SSV6_9RHIZ Transcriptional regulator OS=Mesorhizobium sp. SCN 65-20 GN=ABS58_07645 PE=4 SV=1 +----------------------------------MRAagHGWFSEGRAGLLGHIPRRGTRQAGLIDRTGVSKQAVQQLLDGLEAEGVIERASDPDDKRGKLVLYTPKGLAALDDGDRIKLDIETRYRDHLGEGTFEALMAALSGLAEPRAK--- +>tr|D7DRT4|D7DRT4_METV3 Transcriptional regulator, MarR family OS=Methanococcus voltae (strain ATCC BAA-1334 / A3) GN=Mvol_0184 PE=4 SV=1 +----------ERSENNSINHLLYSIKTELCKKCNqsFKELGVTGSQFNVLEVLWHKDGITQSEIQRYLGIKASSVSNLIDHLEKKELIERVFDENDSRVKLIYLTKKGLELKEQGYEKCSAQTEMILSGFSDAEELELKNYLKRLISNLG---- +>tr|A0A1J0GMA2|A0A1J0GMA2_9CLOT Uncharacterized protein OS=Clostridium estertheticum subsp. estertheticum GN=A7L45_02795 PE=4 SV=1 +----------MGNEEMWIGYWLTKSVRLLNKFHDnkLQKYDLTSSQVAVLQKLWGEDGKTQKQLQENLGLTPASVSGILDTLANKGFIVRKHDEIDSRVNRIYLTLEGAKLEKLCHGIINEIEKTISDGFTCDEIKIFIAWTKKMHKNIC---- +>tr|A0A1C6HVZ3|A0A1C6HVZ3_9FIRM Regulator of autolytic activity OS=uncultured Anaerotruncus sp. GN=mgrA PE=4 SV=1 +----------ELGDMPRISYPVSTLYRRMQRYLSrkLAEegLPVEAGQLPALLHTYWHPGITQDGIAAGVGIDKGTAARALARLEELSLICRVPDEVDKRVRRIHLTEQGLAIRQQVMDIYSQMYEILYQGLSQQEIAQAAALLGQLSENMH---- +>tr|A0A1C6LW86|A0A1C6LW86_9BURK DNA-binding transcriptional regulator, MarR family OS=Variovorax sp. HW608 GN=VAR608DRAFT_0496 PE=4 SV=1 +-----------------------LRRSAFDRSMKPLGI--TRSQWWVLAYLSREDGMTQSRLAEELDLGKVAIGGLIDRLQKSGLVRRVADPADRRINRVFLEPSSKRMIARLRSVEAQLNEEILEGVTERELEVAAATLATIKHNLLKY-- +>tr|K4MQ58|K4MQ58_9EURY MarR family transcriptional regulator OS=Methanolobus psychrophilus R15 GN=Mpsy_1880 PE=4 SV=1 +----------------SIGRDAFLFSREIHTFIAreMEPYGIGSGQFPFLMRLLHHDGISQEVLIRDLNCDRATGTRAINKLEENGYVLRETDPQDKRAYRVCLTDKSRQLEPVIKQMSVLINDIVFDGFTGEEKILFVQMIKRAIGNLSR--- +>tr|A0A0M9DS05|A0A0M9DS05_9BACT Uncharacterized protein OS=bacterium 336/3 GN=AD998_06295 PE=4 SV=1 +----------------AVGLYFYLLDKLYQRLLSydLDFTGLE-RYFMVLWAIDESESLTQQNLADLLKIDKASVVRIADDLEKKGFIQRVMNPMDKRAYFLELSKKGNKYIKDIHEGIDNLNSEMFIGFTQKEKEIFVELLNKAYLNLSQ--- +>tr|V5WL35|V5WL35_9SPIO Transcriptional regulator, MarR family OS=Salinispira pacifica GN=L21SP2_3021 PE=4 SV=1 +----------------SFGLWISIINRSAQSYFYhkLEPFGLGTGQQAYLLALLPGEEIVQDQLAQRLQIDRANVTRALGSLIKSGYVQRRISPEDRRARLVSLTEKGTEVRREVEGIASQWIETLQKAVSADEWNQSEQTLRKIALSLHE--- +>tr|W0EQ88|W0EQ88_9FIRM Uncharacterized protein OS=Dehalobacter restrictus DSM 9455 GN=DEHRE_03660 PE=4 SV=1 +----------------SPGSRIAVLYRMDRDFFAkkLKEYCLGTSEMAVLLQLSYYRELSQDQISTNIVMDKTTLSKIVKKLLHKGHIYMVRDTQDNRVHLLGLTQKGQEMIPVLKDATAEWVSIISKGFEPEEITLFCNILDRMIVSVEA--- +>tr|G4HL21|G4HL21_9BACL Transcriptional regulator, MarR family OS=Paenibacillus lactis 154 GN=PaelaDRAFT_4682 PE=4 SV=1 +----------------AYGKEVTAINRHLQLLLSprLAALQLGFGQHMFLLMLSRKEGMNQKTLSEQLLLDKTTTAKAIRKLELEGYVRKEMDPADLRNHQLFLTDAGKAVVPKIEEALAEVMEIGIEGMSAEEYGEFMRLLKIVLNNFDK--- +>tr|A0A101J001|A0A101J001_9EURY Transcriptional regulator, MarR family OS=Methanomicrobiales archaeon 53_19 GN=XE11_0540 PE=4 SV=1 +----------------RVTKKIGYLYWSNRTLFTkLFPHPLGPGQAAFLIYLTEDTEVRQETLASMIGVDKAIGTRVIRKLNEAGYIRRRRDPENYRAYLISLTEEGNEMKDAILEVSNFIDESLLNGFTDEERDMMHNLLDRMIVNIGQ--- +>tr|D4H6X7|D4H6X7_DENA2 Transcriptional regulator, MarR family OS=Denitrovibrio acetiphilus (strain DSM 12809 / N2460) GN=Dacet_1067 PE=4 SV=1 +----------------SAGKQISHISRSISRYLDakVNSLNLSYSVIPFLTYLYEHDGVHQDELAANLHYDKSSATRAITALVKQGYVTRQIDKRNKRRNIINVTIKGYTIKDELILILRRTTQKLFNDFTDEEINLYFKLSDKIDKNLDN--- +>tr|N1Z975|N1Z975_9CLOT Uncharacterized protein OS=Clostridium sp. ASF356 GN=C820_02838 PE=4 SV=1 +----------------SIGRIVMLLSRSICNDVRyvIEPFGLTVGEESYFIALAHEDGLTQDELSSRVNVDKSATARAVKSLEAKGYIEREIDPFDRRNKKLYFTEKAKKVYISLSEALGKYNQQLTNEWTDEQYNLIYESLEMLQLKLEI--- +>tr|I2EVT9|I2EVT9_EMTOG Transcriptional regulator, MarR family OS=Emticicia oligotrophica (strain DSM 17448 / GPTSA100-15) GN=Emtol_2656 PE=4 SV=1 +----------------VFGSTIRALHKATALEFDKSGLEISPEQYHLLKIIASKEDSIQAELAEIMQLDKSGIMRHIDQMEARGFVQRVNDAQDRRKKYIVLTESGIQKLDNCKIALDKMANTILKGVSDAELLIFKQVLTKLKENAGG--- +>tr|A0A1F2PCW9|A0A1F2PCW9_9FIRM Transcriptional regulator SlyA OS=Acetobacterium wieringae GN=ACWI_32510 PE=4 SV=1 +----------------DFGKMIRTITANTNNYIGgmIEKFGIRQGQFEYFLLIYGSPGINQNELARLKSVGKASVTKALKILEDDGFIRRVSDDVDKRNTRCYITGKGELIVNDLLKIRAEAEKVLFDGFTEAGKAALYEHLFRLYQNSEQ--- +>tr|A0A1F9ZTU3|A0A1F9ZTU3_9FIRM Uncharacterized protein OS=Firmicutes bacterium GWF2_51_9 GN=A2Y20_04850 PE=4 SV=1 +----------------NIGRSMSILHRQAQVFHThsLKSFGISAGEYPFLLYLYTHDGCTQDDLVNALTIDKAATARAIASLEEKGYVSRGKIDADKRCNHIKLSDKAKENEVEIRRRVYAWSEFLSEDIDPETLKIVEDTLDKMVEKVEK--- +>tr|A0A1M5TAR4|A0A1M5TAR4_9FIRM Transcriptional regulator, MarR family OS=Sporobacter termitidis DSM 10068 GN=SAMN02745823_00012 PE=4 SV=1 +----------------SLSLWFSILYRYRKNYLMkkLERYGVIGGYPYMILAIHKNAGTNQEQISNILKTDKAAVTRAVKKLEKEDYILREPDLSDKRAYRVTLTPKAEAVVPEIRKALQEWEQIAVAGIPEDMLPVLRQYVKQMSDNAVA--- +>tr|A0A1V4TJ57|A0A1V4TJ57_9EURY Transcriptional regulator SlyA OS=Methanobacterium sp. PtaB.Bin024 GN=A4E25_01137 PE=4 SV=1 +----------------PFKGIISIILRNHFVFMNkeLKHLNLTEGQVPCLVALSKEEQLTQDDLARMFHIDKGTIARSIQKLEDKKMVRRVQDPVNRRRYILYLTEKGENIIPEILDAEKKWEDTIFKDFSEEERSFLVDGVESLAKNSLE--- +>tr|A0A1V5SJG0|A0A1V5SJG0_9EURY DNA-binding transcriptional repressor MarR OS=Euryarchaeota archaeon ADurb.Bin294 GN=BWY45_02528 PE=4 SV=1 +----------------PPGPLLSIINRARVIFLNerLKPFKLSAGQYPVFMCLLKHPDITQDTMARYFHLDKGTIARTVKKMEDAEYISRRVDPDNRRAFRLSLTRKGYQIAPEIMAIDQEWEQAVSCQLTKEEKEHLQVLLRQVASSSIQ--- +>tr|J0B2J4|J0B2J4_ALCFA MarR family transcriptional regulator OS=Alcaligenes faecalis subsp. faecalis NCIB 8687 GN=QWA_06775 PE=4 SV=1 +---------------------------------TLGRYGVSEATILPIRYLAQLgEPIRQGQLARMMRLEGPTLVRLIDQLESTGLLERVPDEQDKRARLLCLTDKGRDFHAHLLELLRQSRAPLFAGIPEQDIKAALRCFDMLASNLGLKA- +>tr|U3A0J4|U3A0J4_9SPHN Putative MarR family transcriptional regulator OS=Novosphingobium tardaugens NBRC 16725 GN=NT2_02_03650 PE=4 SV=1 +----------------------------------MREVGVTGAQARLLMILAADEGRQQTHYASVLEVEPITLCRMVDRMVEADLIERSPDPNDRRARLLSRSDKARALEPVLQEKIDQLVDDIQSPFTSDELQILHRLLSRMGEQLVSPS- +>tr|A0A1G2W7L3|A0A1G2W7L3_9CAUL Uncharacterized protein OS=Phenylobacterium sp. RIFCSPHIGHO2_01_FULL_69_31 GN=A2790_08180 PE=4 SV=1 +---------------------------------RVRSLGLTRPQWRVLVYVMQNEGLSQSMLARAMDIERAPVGQLLRALEALRLVRRVRSSADQREWLIYGGEGSRDMMPQLVEAASWLRGVYFQGLTRSEEQMLHRILERMRSNLSYEL- +>tr|A0A078MGE8|A0A078MGE8_9PSED MarR family transcriptional regulator OS=Pseudomonas saudimassiliensis GN=BN1049_02062 PE=4 SV=1 +---------------------------------KMAAAGFADISWSPLIHLAESgDGVSQKALAALVGIDGSSLVRLLDTLESRGHIQRCPCPDDRRVKLVMLTADGQQMVHTIRDHLERIEREMLQDLDDEQLLAMLGGFDRIKDRLALMA- +>tr|A0A0F2PJW3|A0A0F2PJW3_9FIRM MarR family transcriptional regulator OS=Peptococcaceae bacterium BRH_c8a GN=VR67_02820 PE=4 SV=1 +-------------ICYKLSKVMRKVQRYYEASL--VHFEITPVQFYVLSALLSSDGMKFKDLAKSVGIDGSTLTGILDRMARGGFVERRDDPEDRRSLLIYLTEKSKEMGPDMMKLAEKLDRDIKEQFPGAEFATFMKVLDQLSETT----- +>tr|A3ZXC9|A3ZXC9_9PLAN Regulatory protein, MarR OS=Blastopirellula marina DSM 3645 GN=DSM3645_30051 PE=4 SV=1 +-------------LGVAM----RRVARLYTEEL--APFQLTPPQLYLLTCLEQNAGCKPREIARSICVDASSITSLLDRSEQAGLIQRQADPADRRSLQIFLTDLGRRRLATVAETVEALNQRIRDELlapfNDEQVDLFLTMLRGIGKDD----- +>tr|A0A0C1RYU1|A0A0C1RYU1_9DELT MarR family transcriptional regulator OS=Smithella sp. SC_K08D17 GN=DS62_08300 PE=4 SV=1 +-------------VCFQLTSASQKIRRRYRDGI--AKYQLTHGQFFMLCAILEEEGLLPSHLADKTELDRPTATGLLDRLERDGWIERHTEPSDRRMYRISPSAKAIKHKGDLLNLFEQTNSHFIN--rfTPDEWEQFQEYLNRLElP------- +>tr|A0A161TB85|A0A161TB85_9BACI MarR family transcriptional regulator OS=Bacillus marisflavi GN=AV649_16890 PE=4 SV=1 +-------------INFLLSASQNKVFKYFSKLL--EDCGVTPAQYGVLNCLWKEGQLSPKQIGEMVYLEASTVSGILDKMQKLELIERSIDPSNRRNILVRATHKSQAIRDEVEAVTSKMNNKILQNLSDRDTEVLKRALEVIIkSDL----- +>tr|A0A1G2VF90|A0A1G2VF90_9BACT Uncharacterized protein OS=Parcubacteria group bacterium RIFCSPHIGHO2_01_FULL_47_10b GN=A2666_01975 PE=4 SV=1 +-------------IVIKFGRvq--KKLSAFYDRAF--DPFHLTLAQFLLLVVLFERNGRTVKEFGATLGLKGGAITPLLDQLERKGYIERRSDQFDRRAVQIMLTEQGRLSEQALRDLFEETNDKISRLLqakfRKEDVELLAQMVGYVDFSL----- +>tr|A0A1M6S042|A0A1M6S042_9DELT DNA-binding transcriptional regulator, MarR family OS=Desulfatibacillum alkenivorans DSM 16219 GN=SAMN02745216_03356 PE=4 SV=1 +-------------IMFQMAKAYQRVHAEFKSGA--AELGLTPIQCLVLQAVFEEPGLSSGEIGQRLHIDSATLSGILERLIERGWVVKNTSAKDRRVLEIHPTEQAMEQKTALDGMVESLNEKVLASFRVEEKMLLRRMLEDLAQ------- +>tr|A0A1Q9MRT0|A0A1Q9MRT0_9ARCH MarR family transcriptional regulator OS=Candidatus Lokiarchaeota archaeon CR_4 GN=RBG13Loki_3854 PE=4 SV=1 +-------------TFDLLKKVRKRVSDLHRSLI--QKYGLSLSQYCILKQLWDVDEKAFKDLAECCHISRSTATGVVDTLEEKALVSRKTNPEDRRSIFVKLTDKGKSIRQVTPSQDAIVP----K--hkmQGEEIRTLNNLLAKLFkSLE----- +>tr|A0A0Q1BGA5|A0A0Q1BGA5_9FIRM Transcriptional regulator OS=Lachnospiraceae bacterium TF01-11 GN=APZ18_07035 PE=4 SV=1 +--------------------------------TSVKDTGLTSGQPKVLDYLKNHDGAVQKDIAINCHIEPASLTTILNGMENKGYITRNICTQNRKYLNVHLTKLGWKYVERLKKEFAKIENLALKTFTDTEKEQLIFLLEKLYDNLSEI-- +>tr|G7WEX4|G7WEX4_DESOD Transcriptional regulator OS=Desulfosporosinus orientis (strain ATCC 19365 / DSM 765 / NCIMB 8382 / VKM B-1628) GN=Desor_1660 P +--------------------------------ARVRECGMEKGQPRILDYVYVNDGCIQREIRDEFSLDASSISNLLAILEKDGTLRRKRNPLSSREVNVYITDKGREIQKRLEVVYDELEQITFQGFSPEEKEQCIHYLFRLTKNMMSY-- +>tr|D8IC31|D8IC31_BRAP9 Putative transcriptional regulator OS=Brachyspira pilosicoli (strain ATCC BAA-1826 / 95/1000) GN=BP951000_0705 PE=4 SV=1 +-------------------------YQYIGKQI--INFDITPEQLIVLKELAKEEGISQKELSIRLDKDQNTVKAMIDKLEVKSFIKRKENKLDKRAFSLYLTEKAKKELPIIENYENQVLDTIVKELNLNDAEIIKNTLKKIRSNISE--- +>tr|A0A1V5B2U9|A0A1V5B2U9_9EURY Transcriptional repressor MprA OS=Methanosaeta sp. PtaU1.Bin060 GN=A4E48_00961 PE=4 SV=1 +---------------------------MVQQII--KEFKATGQE-SALYAVVRNSGISQTEIARISIKDKANVTHIIDFLEEKGYIKRVSDHKDRRVNVIVPISGGEEVLERLIGVAQASNEAFVQDLTASERQSLKDSLRKISASLED--- +>tr|K5DAA4|K5DAA4_RHOBT MarR family transcriptional regulator OS=Rhodopirellula baltica SH28 GN=RBSH_04807 PE=4 SV=1 +-----------------IGRVAYLMRTRMAAVLKQADWPFTPEETQTLVTLADVGePLSMSDLASRMVRDPTTVKRQLDRLVEHKFIQRSVSPKDARIVMVGLTARGEQQLQTVLPLLDELRKCALQGITKTQVTEIQKVLQKMQSNLA---- +>tr|K0NC11|K0NC11_DESTT Transcriptional regulator, MarR family OS=Desulfobacula toluolica (strain DSM 7467 / Tol2) GN=TOL2_C01210 PE=4 SV=1 +--------------------------------EKIKPLDIQPGHLPFIATLLDNEtPMIQDDIGSHVFIDKSVAARGIDSLEKKGFLNRSINPENRRQKLVELTNMSRNIKQKLFDSLNKASEELLSALSPEEQDRLMDLLDRMLHGAL---- +>tr|A0A0U5Q0J3|A0A0U5Q0J3_9RHOB DNA-binding transcriptional regulator, MarR family OS=Rhodobacteraceae bacterium HL-91 GN=Ga0058931_2886 PE=4 SV=1 +---------------------------------ALRPYGLSFAQFCMIDLIDRGGPHYPSSLARKLDIETSTMASTLKRAEGAGFIIRSPDPNDARGVVVTLTEHSREILPEARAAVLGIEEKCTGDLSGDERK-GGIEFLQRIGNSLGM-- +>tr|A0A1M3KU58|A0A1M3KU58_9RHIZ Uncharacterized protein OS=Devosia sp. 66-22 GN=BGO81_08330 PE=4 SV=1 +---------------------------------GLVPLGIAPPMFPLLVELWFGdTPVSRASLAATQEMEVADIDALVVAMAEAGLIERFAA---DPAAVLVLTAKGEAAKGPAVAAARRANAAAAAVLDEAEMAQLLGLMNRVIDALQGA-- +>tr|A0A1S1XDN6|A0A1S1XDN6_9NEIS Uncharacterized protein OS=Chromobacterium amazonense GN=BI343_09065 PE=4 SV=1 +---------------------------------RLQGTGITRSQRQILLMLHQSGDCTQKNLLGQLDMDPGQLARTLEGLEKDGYIRRRPWAANRRCMFVEMTEHCRDKLMpGLLAAVDSVDQQLFQGFSPEEQQKM-QTMLQRMQTNLSQ-- +>tr|A0A1L4A076|A0A1L4A076_9SPHN Uncharacterized protein OS=Sphingomonas sp. JJ-A5 GN=BSL82_17650 PE=4 SV=1 +----------------------------------IRDSGLRLSHWLTLKYIADGRICFIGDVYRELGITDGASTRLIDHLEQKGLVRRNRSRKDRRLVAVALQPEGERMVRQLRLRIERRWQRQLGPFCEADRIHITTALIHLIDAFRS--- +>tr|Q0G3J3|Q0G3J3_9RHIZ Transcriptional regulator, MarR family protein OS=Fulvimarina pelagi HTCC2506 GN=FP2506_15434 PE=4 SV=1 +------------QIALGLFDAARLLREAFEHAH--RDMKITWPQIRIMGRLYVQEGIAQSEIGAQLEMDPMTISRQIDRLVDLGFVERRTEQRDRRLRKLYLTRHSRILREDIEKRTQSVLNTALHGFDAERQASFLEMLKTFADNLCEP-- +>tr|B1KGY5|B1KGY5_SHEWM Transcriptional regulator, MarR family OS=Shewanella woodyi (strain ATCC 51908 / MS32) GN=Swoo_4041 PE=4 SV=1 +------------ELAKLLVQNERLLDKKLESALQQRKKTLGNVQWRILTNLIEASeGLSMKDLSLLTHTNDSTLTKVVDKLVNDSLVYRRPHPKDRRKILIISSSKGKALHAKLESDVNQCYEKMFEPLSAQQMKSLQNILQTLNNEGSLT-- +>tr|A0A1C4XKM2|A0A1C4XKM2_9ACTN DNA-binding transcriptional regulator, MarR family OS=Micromonospora mirobrigensis GN=GA0070564_103165 PE=4 SV=1 +-----------------MDDAaATLLAVWEAARER-TTSRLSSAQLRAVMVVEQHDGINLRRLATRLDMLLSSASRLCDRLVAAGMLEREPSRTDRREISLHLTPEARRLLAELRTDRRRRLAGVLAAMSPAGRQALLVGMREFDEVARER-- +>tr|A0A1L5M1J7|A0A1L5M1J7_9BRAD MarR family transcriptional regulator OS=Bradyrhizobium diazoefficiens GN=BD122_04640 PE=4 SV=1 +------------NFLFTLAELYRLLRVYADKEA--SRFGITRAQWAVLAKVERSEGMKQSELAELLEVQPITLTRLIDKLCDNDWIERRSDASDRRVKRLYLRKAGRQLLGKMSGLRSEITANALDGINPADAHRLLTQLEAIKENVRTA-- +>tr|A0A1V9KCX1|A0A1V9KCX1_9ACTN MarR family transcriptional regulator OS=Streptomyces sp. M41(2017) GN=B0675_10190 PE=4 SV=1 +------------QDLFsrsalAVFRLNGQYLSVAEDLA--RPAGITAAWWQVLGAVLG-EPLPVSGIARVMGITRQSVQRVADLLVDKGLAAYRPNPAHRRAKLLAPTEQGRAAVATIGPGHAAYADRIAEALGPEALAETVRVLERLSVVLDGL-- +>tr|R5MHS4|R5MHS4_9MOLU Transcriptional regulator MarR family OS=Mycoplasma sp. CAG:956 GN=BN817_01143 PE=4 SV=1 +--------------------HIINTDKLIGRYILdkfdkKARHRISPMQVMIMNYLLKNQNKkvFQQDICDTFNLRRSTVSGILTTMEKNDIIRRKVDTEDPRKNEVKLTKIFINNTKRVSNELVKMESILEQNFTQEEKKELIRLLQKLEGNLIKE-- +>tr|R7HDZ5|R7HDZ5_9MOLU MarR family transcriptional regulator OS=Mycoplasma sp. CAG:472 GN=BN672_00464 PE=4 SV=1 +--------------------DIKIFHQLVINSIGvkdmPKYPSVTTTQIQIMEYIISRPKKcaLQKEFEKVLGLSRATVSSVLITMEKNGLIVRITDNTDTRTKKIVLSSNAQRVFNSSKEKIKKIEDICLKDITEKDLNTFINVLSKMTENLKEE-- +>tr|A0A0N1MK69|A0A0N1MK69_9FLAO MarR family transcriptional regulator OS=Chryseobacterium sp. ERMR1:04 GN=AMQ68_06545 PE=4 SV=1 +-----NISEIALELGLAMGEMKSRLRQKIQAKINEYDPDLSFELIEILGLLSRNNGINQQEISSKVSKDKSSITYLINSLVKRELVERVENTTDRRNKQIFLTVKGNEIVETVYPWALELYKKAADDLDEDDINRALLLVKKMTANL----- +>tr|R5USX4|R5USX4_9BACT Uncharacterized protein OS=Odoribacter laneus CAG:561 GN=BN709_00763 PE=4 SV=1 +-----DIRELVVYLSKA----ERGYTKTLNRAFQQAGYDLSREQFELLQVLWEGDHINQQAISRKLQKDKYNVTKLLNTLTKRGFVQRTMSQEDRRNNFVILTEKGMQVQKALLQIEEQVHTDLTFTLTPSEIKSCMWVMRKLTDMM----- +>tr|A0A1M7AVM5|A0A1M7AVM5_9BACT Transcriptional regulator, MarR family OS=Chitinophaga jiangningensis GN=SAMN05444266_103428 PE=4 SV=1 +-----EIADiLRSAVSRNITRAHTAYRLRLLAVFMEKGVDLTPDMYFILRHLWGeQDGCRQQELADKTDKDKASLTKLVDNLEKRGLVRRSMDGEDRRSKRVWLTPVGKDLKEIVYPLALQVVATAENGVDQEDIQRVKQTLDALVKNL----- +>tr|A0A0F7M0W9|A0A0F7M0W9_9GAMM Transcriptional regulator, MarR family OS=Spongiibacter sp. IMCC21906 GN=IMCC21906_00256 PE=4 SV=1 +--------------------------------IQEHQISLPINHIRVLKGICRLPDSTAQSIAHKMNQDKAQVTRVLNALLQSGFIEKSEKPSDRRSQLLIPTIAGQKMLSKIDAIEEQAAAYMTRNLNTQDLEAFVRISNAMLEKPSKA-- +>tr|J8T753|J8T753_9ENTR Multiple antibiotic resistance protein OS=Pectobacterium wasabiae CFBP 3304 GN=Y17_2786 PE=4 SV=1 +--------------------------------MKAHDINLDVVHIRLCKIIAAAGRITPQLLAKTVGRDKAQITRMVAELVKRDYVRKIDNPDDGRSVWLSLSDKGIAFTQVFLHQEKHIEAQMLQALSSDEQAMFSALLEKIAASDSAH-- +>tr|A0A0C1PUP1|A0A0C1PUP1_9GAMM MarR family transcriptional regulator OS=Pseudoalteromonas elyakovii GN=QT15_01195 PE=4 SV=1 +--------------------------------VREQGIDMVPMEIQSLHLINRTENCTAALMSELMDRDKSQLARLIKEMSKKGLIEKTKNPNDTRSHFLGLTEDGKAILKRMLVIEAGLIQKMCTDLSHEQVEVFNNIAVIMTANLARE-- +>tr|E8V5D8|E8V5D8_TERSS Transcriptional regulator, MarR family OS=Terriglobus saanensis (strain ATCC BAA-1853 / DSM 23119 / SP1PR4) GN=AciPR4_4151 PE=4 +----------------------------------LRPYDIGSTQWYVLYQLANEGPTMQRDLVRMLQIERATLSGVVATLVRKGLVDQAPDAVDQRQRVLRITASGKKLWKTLPDPITLILATAFDGMNPAELAVARRVLQTATQRLNAH-- +>tr|T4VQH4|T4VQH4_CLOBI MarR family protein OS=Paraclostridium bifermentans ATCC 638 GN=C672_2304 PE=4 SV=1 +----------------------------------LKDRNLGQGQLLTLMTLfklKNYDEITQEDLAKVMGINKANTSRNLAKLKESGFIVINQSKDDQRKKNIELTNKAFEEFLYLEKIMREIHNEMISGLDSDSLDSTLSTLIKMKENLLNK-- +>tr|A0A223B2C5|A0A223B2C5_9FIRM Uncharacterized protein OS=Eubacterium minutum ATCC 700079 GN=AXF21_04975 PE=4 SV=1 +----------------------------------LQIIDFSWREMVVLMVLEKKPGATQNFVGKFLQTDKSNVTHIIQGLETKTFLIRKTCEKDRRYKGLYLTSVSRKLLPWLHEQLRLWQEQCYQGLSQEEITIYQNLNQKIIDNLFAF-- +>tr|A0A085WPF3|A0A085WPF3_9DELT Transcriptional regulator, MarR family protein OS=Hyalangium minutum GN=DB31_6541 PE=4 SV=1 +------------RLRHLLIdVGRQGIFSSPLA--APAEGDMEPLHFESLWWLRAEGFLTINTLAErLGGVAMPRMSRMIDRLEEAGWVQRVKIvREDRRHVSVRLTDSGRAQAEQVDALVQARMARLLLPLAGEDRSALMDLLERWVEA------ +>tr|W0VAN4|W0VAN4_9BURK MarR family protein OS=Janthinobacterium agaricidamnosum NBRC 102515 = DSM 9628 GN=GJA_4050 PE=4 SV=1 +------------RLARMTSHIQKGLKDSTNA--ALKKHDLTDVSYMVLAVLYGTedASSNARTLGIACNEKPANLTRVCNELEQRGLIHRGSRPGDRRSVMITLTDAGRALICLALPDVYRRNVHVYDGFNAEELQQLEKMFARQLHN------ +>tr|A0A1A9DDM6|A0A1A9DDM6_9ACTN DNA-binding transcriptional regulator, MarR family OS=Streptomyces sp. OspMP-M45 GN=YUMDRAFT_06550 PE=4 SV=1 +------------HVPYLLAVASTVAARRVDE--RLAAYGLTVRQYGLLAQLSLEPELTMAELARQLGIARQSVHQLVNELVGAGHVRRRPGADDR-SRRLEITDTAHYLLTRIDGPLERVEAELLGELAPDEAETLRSLLQRVLAH------ +>tr|A0A1E7Z733|A0A1E7Z733_9ALTE Uncharacterized protein OS=Alteromonas confluentis GN=BFC18_18105 PE=4 SV=1 +------------DFGKHIAMVRNLMMSRLDE--LLKEFDLTGSQYAVIKHIAEGRADTLAKLCELLQYDKGAMSRILSRMEDKSLIIRKPCPDDGRAFRLKLTPRGKELFPQTTPKVNALFEQALAEFSAKEKEAFFSMLERCRSN------ +>tr|A0A1Q3SVD8|A0A1Q3SVD8_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium 39-13 GN=BGO43_09510 PE=4 SV=1 +------------SIGYLIRRASKLVISQVEA--LFAEQDISFTQYVVLVLLRDNLASTASDICQQLGYDTGALTRVIEQLRRRELIERKRNIKDKRIISLSLSPLGRETIENFCPLVFNHYNQRLEDFSFKEIDTLLTLLTKFIAS------ +>tr|A0A149PR57|A0A149PR57_9BURK Uncharacterized protein OS=Paraburkholderia monticola GN=CI15_15230 PE=4 SV=1 +------------KLMSVLGQARQLIAGELRA--GLADAGLNLQERAVLLTLAHGSVRTPAALSKLAGVHPARMTRVLDKLESNGLIERARNGRDRRLVDVSLTREGQAVAARNARVALGAWSERLSHFSKSDFDTLSALLSRLIGH------ +>tr|A0A1L6HW43|A0A1L6HW43_9BURK Uncharacterized protein OS=Paraburkholderia sp. SOS3 GN=BTO02_09940 PE=4 SV=1 +---------------MALRRTGDLVIHEIDA--GLSDFAVNFLQLSMLVAIASGRAHSPAGIAQKLDVDRAVVTRALDKLEANHFVQRRRSVDDRRNVLVSLTEPGAISFNKLCNVASAILRARLGKVPSGECEHLQCLLALVRGV------ +>tr|A0A1Q6RTJ7|A0A1Q6RTJ7_9FIRM Uncharacterized protein OS=Firmicutes bacterium CAG:176_59_8 GN=BHW34_01820 PE=4 SV=1 +------------HFGPLFGYCHHQVQKLMNR--LLRQYDVSPMQCRTLTFLHDAeGEVNQKALEKHLMVKPSTVNGIVDRLEEKEMLRRTTSKTDGRCRILELTDQGMQFYDNFTAVVRQVDTRLERDFTDEEKKLLLSLLMRVARN------ +>tr|A0A1Y0H0N9|A0A1Y0H0N9_9BACT Uncharacterized protein OS=Armatimonadetes bacterium Uphvl-Ar1 GN=CCB80_11060 PE=4 SV=1 +-------------------------------------AGIRWTTFQLLAAViG-aGDQASQAEIARRLAVAPATLSEAVQTHVRQGLLIQAPAPTDRRKKILQLTPEAKRKMSKVAVHVQTLEQLLTASISPKLIAETETALEKM--------- +>tr|A0A196PK79|A0A196PK79_9RHOB Uncharacterized protein OS=Sulfitobacter pontiacus GN=A8B81_12580 PE=4 SV=1 +---------------------------------Q--HVNLTPIQYTILVIIDMEPGVEQTSIASRAGLDASTVADVVKRLVKHGMIKREVGIRDKRSRVAFITSSGKAAITDAAPLIEDAIQNMLSPLASDEQQNFLSMIDRILTHNT---- +>tr|U2NPZ7|U2NPZ7_9CLOT Transcriptional regulator OS=Clostridium intestinale URNW GN=CINTURNW_2306 PE=4 SV=1 +---------------------------------NLDKYDLTTSQWAVIKLLYNKKELTQAQIADELKSDRATAGNVILNLYEKKYVDKRIGEKDRRTYIICLTEKAMKAVNEIELIAEEVTRKALYGLDDKHIKIMYEGLNKVINNLSEG-- +>tr|R7HRQ0|R7HRQ0_9CLOT Transcriptional regulator MarR family OS=Clostridium sp. CAG:768 GN=BN776_00091 PE=4 SV=1 +------------------ARVAEL---MARNCYKIYQdtdkPILDLDEFKIISHIMDDPDLSQSDIAKLVYKGKAHVGKILNELEKKHYIKRDLTTRNNiIIKHTIITEQGKEIYFYTDERFKEINQNIKKMFSEEELNTLKALLDKLKIAMLN--- +>tr|R7LRX3|R7LRX3_9FUSO Transcriptional regulator OS=Fusobacterium sp. CAG:815 GN=BN791_00428 PE=4 SV=1 +------------------AKYCKY---LGMQIFQKLDLPISLDEFVILDILIDNEEICQRDLAKLILKDRPCTGRLLNSLEKKGFIKRFVDTKNNrLVKKMKLTSAGIETTEKVTIIIKNYMDKLPKVLSDDDKLELINSIKKFRESLEK--- +>tr|A0A1Q6TTX0|A0A1Q6TTX0_9GAMM Uncharacterized protein OS=Acinetobacter sp. CAG:196_36_41 GN=BHW62_04180 PE=4 SV=1 +------------------SRVLHE---ATRCFFELQKFPISQEEFIILDCLYINPNIIQMEIAKLILKGRAHTGKFLKSLEEKKLITRTPVKQGSkIVMQIKITDKGLKTYRKIANALDEHIKDASAGLK-IRINDVISALQTIREDAVT--- +>tr|A0A094IK15|A0A094IK15_9BACT HTH-type transcriptional regulator MgrA OS=Candidatus Izimaplasma sp. HR2 GN=mgrA PE=4 SV=1 +-----------------------------------ERLNITYSQLMVLRVANQEPGITAKEILMQMDTDKATLSGVLARLERDNYIYRVKNEKDKRIQNIFVSEGSERLCTEVSVIERACISDLIDGISDTEAENFLSILDRFIANQ----- +>tr|A0A0C5BVF2|A0A0C5BVF2_9ARCH Putative Transcriptional regulator, MarR family protein OS=Candidatus Nitrosopumilus piranensis GN=NPIRD3C_1024 PE=4 SV=1 +----------TDSIGLMMKRSAKSWERATDI--EMtERFGLTGGKWKTITGLSIKEGITQKQLADMMFVEAPTLVPIIDKLEKEGYIVRKTDPNDRRNNLVFLTDKAKKTTDSIIDCISEMRDVGLEKISKKDLEITKKTLMQINANADAF-- +>tr|Q0W653|Q0W653_METAR Putative transcription regulator (MarR family) OS=Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50) GN=RCIX763 PE +----------SEAHALLPGLVKVMWAMRVDR--PSawspAFEGLTPLDLH-ILAFIEaRPDVILKELRNYLDVPNSTLTGLIDRLEKKGLIERVISGRDRRSFGLKLTAKGADLRKEQQQVRLASASKMLGALDsDEERRAFVGMLNKIGDRLILG-- +>tr|A0A0X1SZX1|A0A0X1SZX1_PSEAA MarR family transcriptional regulator OS=Pseudomonas agarici GN=AWM79_08665 PE=4 SV=1 +----------EHRFGMQLAHMSRGWRAELDR--RLAGLSLSQARWLVLLHLARfAQAPTQRELAQSVGVEGPTLARLLDSLETQGLVQRQAVLEDRRAKKIVLCPSACPLIEQIETIATALRHELFVGIDEEELRICMRVHSRILANLEKS-- +>tr|A0A0J1HF88|A0A0J1HF88_9GAMM MarR family transcriptional regulator OS=Photobacterium ganghwense GN=ABT57_06760 PE=4 SV=1 +---------QDLSLAEQLARVSRLWRMVADR--ELAPLGLTHPRWTALWKLQRLGdNISQKTLAEALEIELASLMRTLKQLEEQGLIVRHCCDHDKRARIVSLTEEGRTLIAQMETRILQVRRNLLTDISEQELMRLSEVLETIANNALT--- +>tr|A0A0M8U120|A0A0M8U120_9ACTN Uncharacterized protein OS=Streptomyces sp. XY431 GN=ADK60_38225 PE=4 SV=1 +---------MRTSVAPKLHLTAKSCRAFFEE--RLAEAGATFAAWTVLAALKLEGPMIQRALAQYLSIEGPTLSRHLESMERRGLVVRKRTDVDRRAATVEIAPDGEEMYNRISSVAISSQQDMLKGLSDREVAQLATLLDRILENVGP--- +>tr|A0A1G0LZ37|A0A1G0LZ37_9BACT Uncharacterized protein OS=Gemmatimonadetes bacterium GWC2_71_10 GN=A2085_04985 PE=4 SV=1 +---------------------------------FARDHGLSPPEVRCLAAFGDEPELTAKQLTRRLGFCHSRLSHVLDSLEGHGLISRRINETDRRIIDVSLSGNGLDLVARLEAAVFGCYEPPLRSTPRRATETAVAVLARAFAA------ +>tr|A0A1Y5GHD3|A0A1Y5GHD3_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium 45_16_T64 GN=A9Q99_25445 PE=4 SV=1 +-----------------------------AKRIKRAGINLTPEESVLMNQLWDRDNQTLGELGQWSVKDSSTLTRQVDGLVKKGYVERVHGTEDRRNVFVRLSDSGKKLKIAFRKTGVANLDQDMIHHSEAEVNKALTLIMAVRERALK--- +>tr|A0A0A6V9I9|A0A0A6V9I9_9BACI MarR family transcriptional regulator OS=Bacillus ginsengihumi GN=NG54_13315 PE=4 SV=1 +--------------------------------LINGDKKITRLQWTLLCHVGKSEHCTMGNLADHFNVNMSTVSQMIDRLEKWGYVERGTSAHDARVKIVSLTEKGETIIKEVRAAYLQQLASGLNKFSEDEQDTFIGYLQQLAENLRDV-- +>tr|A0A1F9PIM9|A0A1F9PIM9_9DELT MarR family transcriptional regulator OS=Desulfuromonadales bacterium GWC2_61_20 GN=A2005_08595 PE=4 SV=1 +--------------------------------LVHEGIDLTSNQYKTLLAVAGRGECSLGDLARTLEVAMSSASQMVDRLVSSGLLLRAPAIDNRRQVVIRLSPQGVTLIAELQQATLQGYHKVLARLPEQEQEDLVTAFETIATILNKL-- +>tr|D8WWQ2|D8WWQ2_9FIRM Putative MarR family transcriptional regulator (Fragment) OS=Clostridia bacterium enrichment culture clone BF PE=4 SV=1 +-----------AEVTQHLLNVYRQLYNRYNEFA--AKFELTATQLASLERLWLSEGITVGELGQIIGIERSSVTGLVNRMVAKKLIVKNQDQTDKRLMRLYLTRNAKERLATKKSEqysfSRTIGDYLESQLVSDEITQLNLLLQKVGTALEK--- +>tr|I2IH00|I2IH00_9BURK Transcriptional regulator OS=Burkholderia sp. Ch1-1 GN=BCh11DRAFT_05466 PE=4 SV=1 +-----------HSLLHVMSRTNVAMWQLVTHKT-HAMGGITGMQASVLLLLMYRHSATSMDLAREYKLHSSAITRLVDRLVRLELVERIPCENDRRATYLRATSRGRRISEQLPAIFTDAFETLFDGIDERDVDTLRRCLKHILLNARA--- +>tr|A0A0P7W2E9|A0A0P7W2E9_9RHOB MarR family transcriptional regulator OS=Oceanicaulis sp. HLUCCA04 GN=HLUCCA04_11470 PE=4 SV=1 +-----------RRLYLLLEITARRLHRTADARL-RREAGVSAAQSAVLFLLMRRGERRMGAISETLALGAPAVTGLITRMEAAGLVSRSTDSGDRRGAIVTLTEAGRELAVKADQVLRDINLELAERLGDEDTDRLHDLLGRLNSDEAG--- +>tr|A0A1E4LUR7|A0A1E4LUR7_9BURK Uncharacterized protein OS=Comamonadaceae bacterium SCN 68-20 GN=ABT02_07530 PE=4 SV=1 +-----------PRLVYLLGSAQRRLQQWIAVQQEraalSGARPPTPAQAGVLFVLARSDGVAMGQLAEALDLAPSAASGLAQRMEALGWVARRPSPHDARTLQLWLLPAGQAQLPGLRTATQCINQRLTAGFTDAELHTVARWLEHVQTLGAP--- +>tr|A0A1N6DCJ6|A0A1N6DCJ6_9SPHN DNA-binding transcriptional regulator, MarR family OS=Sphingorhabdus marina DSM 22363 GN=SAMN02745824_1809 PE=4 SV=1 +-----------------MQKAHSSLFRAADRFL-GEEVGLSTSQHAVLLILMQHDGAPISAIAGELKMGKSSLTGLIDRMEKKGLVSRRQSADDARSFEIHIRDHGRHLVRSTLPGTKRINRSILEPFSAQEQEVIARFLNHVASNADE--- +>tr|A0A1X7AN67|A0A1X7AN67_9GAMM DNA-binding transcriptional repressor MarR OS=Endozoicomonas sp. S-B4-1U GN=EHSB41UT_03344 PE=4 SV=1 +-----------NNLYFLLNTAQQTLFRQVDQQA-LQLVGVSAAQITALHHLQSMNGCMQADLGDALGLGKAATSGMVSRLEKNGLVKRLPSPTDGRGYKLMLTEDGEKAIVRSRPLLNQLNVILEDGFKESELVVIRRFMHTVVDKLTA--- +>tr|A0A1W9TC88|A0A1W9TC88_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium 4572_123 GN=B6I22_06015 PE=4 SV=1 +-----------DCIFFQLAKAHQAGARFWTRKL--SGFNVTAVQGMVLGFLSENDRITARKLGERTMLDSATLTGILDRIEKAEFIERRPHPEDRRALQVCLTSEGRVLGETLLERSIAANREFLGRLTDEEQMILRILLKKLRGKDSG--- +>tr|A0A0P1H3P4|A0A0P1H3P4_9RHOB Transcriptional regulator SlyA OS=Phaeobacter sp. CECT 5382 GN=slyA_2 PE=4 SV=1 +----------------LLNRIVHRYNQSVKA--DIKGAGLTTVATRIIVSLKVYGQMTVNELCVHAIAEQPAMSRALDKLEAEGRITRRVSEEDSRSRVVELTESGAALYEQVWPVLTGANETMLKGLSSEDREALQRILMTVLKNIRK--- +>tr|J0JNM3|J0JNM3_ALCFA MarR family transcriptional regulator OS=Alcaligenes faecalis subsp. faecalis NCIB 8687 GN=QWA_02660 PE=4 SV=1 +----------------QMATIIYKLDqTLRST--TLREHNMTYVHFRVLQYLWDKDGCSIGEIAKAIVVHQPVLSRVLDQMQDRGLVQRRTDETDSRYMRVFLSDTGRERYAQVWPPAKAMIDNALSVLTVDERQDLGRMLRSMATHLAN--- +>tr|A0A1E1EYR6|A0A1E1EYR6_9SPHN MarR family protein OS=Sphingobium cloacae GN=SCLO_1003120 PE=4 SV=1 +----------------LVNRLASVGLAVQNR--TLGQQGINTVMLRTLSVLHITNGLTVNEIAVQTFVDQSTASRTIDAMAASGWVERRIPETDMRRREIILTEAGRKLLRDCWPLMEGHCARLTDGIHEADLAACRRVLARMTDNLRQ--- +>tr|A0A1Q4BKR2|A0A1Q4BKR2_9RHIZ Uncharacterized protein OS=Rhizobiales bacterium 62-17 GN=BGP04_07275 PE=4 SV=1 +----------------MLNKVIKVINSALDR--ALQEHGMSVAEWRVLATLGFSKIDRPADIAKFTGIDPSTLSRAFDRLEAQGYVERSRPPGSRRGYSMSLTTLGRSVLRRAIKIVRTQHDELLQLMDKQQAKHFLKSVAFLYQKMGQ--- +>tr|A0A1H7NHM7|A0A1H7NHM7_RUMAL DNA-binding transcriptional regulator, MarR family OS=Ruminococcus albus GN=SAMN05216469_11549 PE=4 SV=1 +----------------FINDISRLFMHRVRR--ECERCGISHGHHKLLMELFQNEGATQLQLVQRTHLTAPTVSVALGKMESEGLVRREADTEDMRQVKVYLTDEGREKVGQVRSIFRGADADMVKGIPQEELDAMTATMRKILKNLLE--- +>tr|A0A1V5PQV8|A0A1V5PQV8_9CHLR Transcriptional regulator HosA OS=Chloroflexi bacterium ADurb.Bin360 GN=hosA PE=4 SV=1 +----------------LLAQVSRLHHERART--RFSALGLHRGQPQLILALSEKDGRTHTELAEYLHVTPATVTKMVQRMENSGFVQRQPDADDQRISRVTLTPAGRQAGEQLSTLFDTLDAETFAGFTSQEREFLQQLLRRVRDNLLR--- +>tr|A0A0R1SPK2|A0A0R1SPK2_9LACO Uncharacterized protein OS=Lactobacillus diolivorans DSM 14421 GN=FC85_GL002455 PE=4 SV=1 +----------------------SVINRLVRNQIThlLSSVDLSDNNFMLIVKIHDNPGLSQKMLVHQIYRNHSIITKQLAKLKKLKFVDVVVNPKNKREKQIFLTNKGESAYLEIVRVSPIVNKWIVEGLTENEAAQFTKLLKKIFENKKD--- +>tr|H3NMR1|H3NMR1_9FIRM Uncharacterized protein OS=Helcococcus kunzii ATCC 51366 GN=HMPREF9709_00622 PE=4 SV=1 +----------------------NAIHWSSIAGRCqtFEEYDILGHQVSYLIAIYKYPGLSQENLRDAMFVNKSTVARNVKTLIDKGYAKSEVDSEDKRVNRIYPTQKLIDFFPKIEKHLDEWNNEILSDLSYEEKVTFENLLKKVALKAVN--- +>tr|G8QQH9|G8QQH9_SPHPG Transcriptional regulator OS=Sphaerochaeta pleomorpha (strain ATCC BAA-1885 / DSM 22778 / Grapes) GN=SpiGrapes_3163 PE=4 SV=1 +----------------------SAIAKYWCIYAHknLQSLEIVGSEHSVIMYLSIQNNISQDTLSTQLVLDKGTIAKILVKLEQKGLVSRVVNEQNKREKIVSLTEKGEEEVKSVYAIVNLWETELLEGISETDQTIFLDVLTSMTERAKS--- +>tr|F3A5U3|F3A5U3_9BACL Uncharacterized protein OS=Gemella sanguinis M325 GN=HMPREF0433_00168 PE=4 SV=1 +----------------------ITILEVMRNYTKepLAKLGITHGHFITLLYISENEGVTQAQLSEIHRKDRNIVSRNINVLEEKGFVIRKRGIVDRRSFSIHLTDLGHSVVSTHKNLIKESEQEALSNLSKDEIAIFYSLLTKIA-------- +>tr|A0A1C6IJI0|A0A1C6IJI0_9FIRM MarR family OS=uncultured Eubacterium sp. GN=SAMEA3545368_00914 PE=4 SV=1 +----------------------SQIYRRTQIYMNerMKDMELSGALAPFVMITYENGKMVQNKFCELMDMSKGTVAKTMNKLEEHGYVTRCGNVEDGRSIDVYPTDRAEEVYPYLVRAGEDWVEIMTEGMTEIERNIFLELLKEVSGNISR--- +>tr|A0A242CVR8|A0A242CVR8_9ENTE Uncharacterized protein OS=Enterococcus sp. 3H8_DIV0648 GN=A5875_003517 PE=4 SV=1 +----------------------SVLYRKMQMGFDklLAPLGLTNGKVMFLFCLDDNGAITQNQICKELDMDKSTVAKMLTKLEKEGFIYKRVNPDDSRAFLVELSAKAHEIMSSAREAHDTWVQLVTSDLTDIEKNIFIELVHKVSQKSIL--- +>tr|A0A1Y3TWW6|A0A1Y3TWW6_9FIRM MarR family transcriptional regulator OS=[Clostridium] lactatifermentans GN=B5G26_15435 PE=4 SV=1 +----------------------SILYRKSHMWLNncCLQHNLTAAQAVVILIICDFKQLTQDEITKRLALDKSVIAKTVTKLVELGFLIRTTNAKDKRTFDIQPTEKSWEVYPFIKEEIEATFQRMTQRMTEKERAEFKRLLSMAAEASID--- +>tr|A0A150XI61|A0A150XI61_9BACT Uncharacterized protein OS=Roseivirga spongicola GN=AWW68_06525 PE=4 SV=1 +---------------------------------GLKAYSVTPEQWQVLIILWNHGSVTPTEISRVTLQDLPSISRMLVRMEKNGWIVRVENEDDGRSFHVQLTEKGRKSKNEMIISLDNHFNSYLQEVPKELHDGIRNELLQ---------- +>tr|A0A1V6LUA3|A0A1V6LUA3_9FLAO MarR family transcriptional regulator OS=Flavobacteriaceae bacterium HSG9 GN=BUL40_03665 PE=4 SV=1 +----------------------KIQDAYLRAFDN-LDVHMTIEQWVIMHQVYNmGEEASQSEITQLNFRNRATISRVIGGLERKGWIKKTRFEGDLKRFKLELTTVGTEIVDKVLPEALRLRRLAVKDLNPTEFANFLKVLDTLGANY----- +>tr|A0A0R1LEN9|A0A0R1LEN9_9LACO Transcriptional regulator OS=Lactobacillus acidifarinae DSM 19394 GN=FD25_GL001011 PE=4 SV=1 +----------------SIGLIARATSSMGN--HLFSQQNLQNNQFLYLLHILDSPGITQAELAAQLHVDPSTCLRTVRKLITGGYLVRQADPADKKRKCLVPTEQAHAFYPQLQHYEQTLLTVGTTDFSAGERLMLEELLARVATNIER--- +>tr|D4MPF6|D4MPF6_9FIRM Transcriptional regulators OS=butyrate-producing bacterium SM4/1 GN=CL3_04260 PE=4 SV=1 +----------------CMLDICRCLDAIRE--GQFAKFGLTRGQHSFLTRISENPGINQENLSYLLKVDRSTTAKALKKLIEKGYIKKIHPENNKKEWILFVTEEGASLNEKMEDLVINPLIQLYQGVSDREITRLYKTMSLMDTNIVA--- +>tr|A0A0R2FCQ7|A0A0R2FCQ7_9LACO MarR family transcriptional regulator OS=Lactobacillus camelliae DSM 22697 = JCM 13995 GN=FC75_GL001657 PE=4 SV=1 +----------------EIGAITRLIQTKSN--AEFRGLGLGNNAFIYVIRACEQPGMFMGELADSVQIDRTTAFRTIKKMVATGWFELKADATDQRLRRVYPTKKAKAVYPRLHAFEQAQSDYLLSGLTPREQTRLTALVKKLKVEEL---- +>tr|A0A1V4SU86|A0A1V4SU86_9CLOT HTH-type transcriptional regulator SarZ OS=Clostridium thermobutyricum DSM 4928 GN=sarZ PE=4 SV=1 +---------------------------------KLCEYGIGCSEYMYIISMPIDSSVNLSYLSNELGVDPALTTKVINSLVKKELVYKHRSENDKRSFEVSLTEKGKQIKPIIRKVLDEWTELMTKGMDNKTKESIIENLEIMVENIK---- +>tr|A0A1Q4BC56|A0A1Q4BC56_9RHIZ Uncharacterized protein OS=Rhizobiales bacterium 62-17 GN=BGP04_26610 PE=4 SV=1 +-----------------------------------KSFGVTHAQFAILQTVHLAPGLEQREIAEAAGYDSVTASHMIRKLEAMNLLRRDKGSRSRRGNSLHLTTAGAEKLKEMEPAIARVQERLVERLPPEKRKLFLQLLSEITGIENV--- +>tr|A0A1M5MR97|A0A1M5MR97_9BRAD Transcriptional regulator, MarR family OS=Bradyrhizobium erythrophlei GN=SAMN05444169_4183 PE=4 SV=1 +-----------------------------------AQFEITPLQYSLLSALAVRGTADQTTLAVDVSLDRTTTTGALKRLQARHFIERAVRRDDRRARVCRLTQTGGALLARMETAAREAHRDTLASLSKSEQKRFVSLMQQIVAASSL--- +>tr|A0A1M2Z0H9|A0A1M2Z0H9_9RHIZ MarR family transcriptional regulator OS=Rhizobiales bacterium 65-79 GN=BGN87_20515 PE=4 SV=1 +-----------------------------------GEADLKPGWFAVLSLIHDNPGITPLVLSRASGRDKSTITPVLRDLLRNHLIEQKPMPADKRSYMLSLTDAGKGRLKELTEHAMEHDRVLDEIVGDS-KPELLRILRLIISSVD---- +>tr|A0A1P8W9D6|A0A1P8W9D6_9PLAN Transcriptional regulator SlyA OS=Fuerstia marisgermanicae GN=slyA PE=4 SV=1 +---------FEESIGYWVTISALAFRKALNEDLAPHGI--TFRQSQVLGWLVLEGELSQSELAARMEVEAPTLAGLISRMEAAGLVARHSCPNDGRRKIIRIEEA-------AKPVWEKIAECArrlraaaTTGLSEEQVRQLLDWLRVVHENLSQR-- +>tr|A0A0R2LFW9|A0A0R2LFW9_9LACO Uncharacterized protein OS=Lactobacillus kimchiensis GN=IV57_GL000093 PE=4 SV=1 +---------------------------------LLKPYQITSGLWPYLAVLQASSNMTQSNLTLELRNDRAMTARSIAKLKQLNYVTGEPASHNKHMQYLRLTSKAETIMPEIRQVVDNAMLEMTRGISETDLQITQQTLQQILFNLTK--- +>tr|C6L8X2|C6L8X2_9FIRM Transcriptional regulator, MarR family OS=Marvinbryantia formatexigens DSM 14469 GN=BRYFOR_05061 PE=4 SV=1 +---------------------------------------KNATQTHILYFLFHDga-CRKiyQKDIEEALNIKSASLSVQLKKMEKSNMIARRKVSGDDRLKEVCPAPAGIALKEQINDEINLLEDILTEGICKKDLDTFYDVVRKMSENI----- +>tr|F9P7G4|F9P7G4_STRCV Transcriptional regulator, MarR family OS=Streptococcus constellatus subsp. pharyngis SK1060 = CCUG 46377 GN=ANG5_0941 PE=4 SV= +------------------------------------IEFMAGPQGQVLHFVnhREDc-GKMtfIKDIEQELGITKSVASNLMKRMVRNGLIYLEVSEADKRAKIIRLTSESKERMNKIRDFFDEMDRCLLTGISEEDLVTFFQIMGRFYQNI----- +>tr|D1AHW0|D1AHW0_SEBTE Transcriptional regulator, MarR family OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_1482 PE=4 SV=1 +------------------------------------DKNLTGMQLAVLLFVgyHnKLdk-NKDifPNDIEKKFNVRRSTVTTILKKLVKDGYITQIRASYDERYKRLFITEKSELIYSKIQQAQIEGEEIVSKGLSQEKIDIFFEVANKIMENI----- +>tr|A0A0P7VYU1|A0A0P7VYU1_9RHOB Transcriptional regulator, MarR family OS=Rhodobacteraceae bacterium HLUCCO07 GN=HLUCCO07_13750 PE=4 SV=1 +---------VSDYLLYLLAAASEAASAQFHAH--VRSHGLRVPEWRVLAWLHDRDGAMITRLARISLIEQSRLTRIIIQMEERGLVLRKGDTRDRRRVRVHLTEKGRGIAETLVADARAHEAALLAQLEGGDGARLKPALAALLARLDPD-- +>tr|A0A0N0IET7|A0A0N0IET7_9BURK MarR family transcriptional regulator OS=Burkholderia sp. ST111 GN=ADM96_23870 PE=4 SV=1 +---------LEQAIPFLLTRAGGRMGNAFAKA--LKPFGLNLSEWRVCASLLYVPHQTLSELSVHATSDISALSRIIDRLESQELVKREKSTTDGRSIRIALTSKGDELALRIVPVAKQHESVILSGFTANDVQVLRTMLLKVYENAGAL-- +>tr|A0A120LTW7|A0A120LTW7_9SPHN Transcriptional regulator, MarR family OS=Sphingopyxis granuli GN=SGRAN_0812 PE=4 SV=1 +---------VDRYPFYLLNRLVSRYNSIIDAR--LRAIGLDIPSWRVLMILGEESPRGAREIAQAAVINLSTMTRIIQRMTAAGLVTATPSREDARVTLVALAPAGEAQLAEARLATAPIYAHLIAGLKAEEFEQLIALLGRLHDNLEPL-- +>tr|A0A1C3WUA1|A0A1C3WUA1_9RHIZ DNA-binding transcriptional regulator, MarR family OS=Rhizobium lusitanum GN=GA0061101_11781 PE=4 SV=1 +---------LEDRLSFLTNRVASAINERFVLK--LQIHSLTIPMWRVLVVLHDFGESKLVDLSSLTSIDASTLSRLTEGMHERKLIRKVRSTKSKREIVVSLRSEGKGLVDALIPQAIELDTFMLAGLSESDMAVTRRALRSMYEQLTAA-- +>tr|A0A1Q4BBZ4|A0A1Q4BBZ4_9RHIZ Uncharacterized protein OS=Rhizobiales bacterium 62-17 GN=BGP04_25755 PE=4 SV=1 +---------VRLNVPYLLGRAANGLLGRLTEV--LKQQDLSLGMWRILALLYAQSPLRFSALFTLSSMEPSTASRFINELLQRGLIAKKKSKTDARGVLLSITRAGQQTVRSLLPQVAVMEKDTLAGFSEDEVYLARRLLQRMCDNVSPL-- +>tr|A0A1W6ZJS5|A0A1W6ZJS5_9RHIZ Uncharacterized protein OS=Pseudorhodoplanes sinuspersici GN=CAK95_00250 PE=4 SV=1 +---------LDDLLPYLMNRLIARMNQNLAEA--LRERGFTFQDWRVLAVLAAHEGANLTELAEATVIPQPSVSRLVANLTRRGYIERQNGATDSRVVHLHITAKGRGIYNKMLPLAVKEYRAATKGFSAKEYDQLRESLLRMMKNRKVS-- +>tr|A0A1U7DLH2|A0A1U7DLH2_9RHOB Uncharacterized protein OS=Xuhuaishuia manganoxidans GN=BV394_14790 PE=4 SV=1 +---------NADRMAHLLKLASKATSRALQDR--LARHDIAYSHWTILRILWNQDSLSVTELSLRASIAKPATVTAVQALDKLGYVTRRKRDGDKKTVYIELTEAGRALEAELVPLAVEVNDIALRGFRETQKAALRKMLSKVIANLDNA-- +>tr|A0A1Y1PVX2|A0A1Y1PVX2_ALCFA MarR family transcriptional regulator OS=Alcaligenes faecalis subsp. phenolicus GN=BV899_12925 PE=4 SV=1 +---------HDTFIPYLLNRSTSALNADFQTL--LRSHELTLLHWRVLAFLNETDGLGVSTLAQYTDVDQTTLSRALVVMENAGHLSRQPDPLDQRRVLIHLHEQGRQHFLRVLPAALDIHHRAIQGFSAEELTQLRQFLNRIRANINGD-- +>tr|A0A219B474|A0A219B474_9SPHN Uncharacterized protein OS=Pacificimonas flava GN=B5C34_06555 PE=4 SV=1 +----------------------------------IHGLGLNRTQWRIITQIARNPLVSQTELGTILELKKATIGLAISSLENAGYINRLRSPDDQRVWQIVLLPKVKTALPVLRDAADDVYKHLWGILSKEQQDFLIETLERMAARTSEL-- +>tr|C0QDU6|C0QDU6_DESAH MarR OS=Desulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2) GN=marR PE=4 SV=1 +--------------------------SFSASLEqRLGGSGVSRVQFMALAHLIALGTMPQKDLAQLLSITSASTVRLVDRLTRDGWAERIPAQDDRRVKLIVPTPKAVEAWEVMSDHAEKITAKAYVGLTREEIDGVKAVLKKVRENLKK--- +>tr|A0A1J0WNS6|A0A1J0WNS6_9RHOB MarR family transcriptional regulator OS=Sulfitobacter sp. AM1-D1 GN=BOO69_20495 PE=4 SV=1 +--------------------------LMRGAFErEIEraQIGVTAAEARVLAHMSVCGGMRQNILADRLGCAPMSVTAFLDRLERAGLIERAADPDDRRAKIARLTPDAQPILEQIQLAGERARGIAFAGVRPEDFEVFRAVCLQLRANLEE--- +>tr|A0A1C8ZVY4|A0A1C8ZVY4_9CREN MarR family transcriptional regulator OS=Sulfolobus sp. A20 GN=BFU36_01220 PE=4 SV=1 +---------------DLIVGLTRKVNKEADKALEELGLSY--FEYKVMCALEEEGKVPMSRVAEKYMLTKAGLTSIIDRLEEKNYVTRIRSEEDRRVIYVELTDKGREKLAQSRKIFGEVIERFMKKLDNNELDNLEKILTKLIG------- +>tr|A0A1F5UXW7|A0A1F5UXW7_9BACT Uncharacterized protein OS=Candidatus Firestonebacteria bacterium RIFOXYC2_FULL_39_67 GN=A2452_10990 PE=4 SV=1 +---------------EYPKKIMKKFGSPIDEDLMKLNLDM--PHVAILDIITHSKIEPMmSEIGKKQGISKAMITRIIDTMEEKGLVSRVEDPKDRRIIRIHVTKIGKGVISKIESHHRNKLKSFLESLSSSDRNLFVNAMRvthKIFDKYGD--- +>tr|A0A1W2G4V1|A0A1W2G4V1_9EURY Transcriptional regulator, MarR family OS=Picrophilus oshimae DSM 9789 GN=SAMN02745355_1320 PE=4 SV=1 +---------------KEFIKTWKIWYRASEKNLINLGIST--VEYRILKNLYERGPLPMIELANINMVTQGWITGVVDKMEKNGYVKRDRSQNDRRVINISITEKGIEFFKHIAELHLNYIDMTLQDFTDYDMNEMIKLLQRVQENVNK--- +>tr|A0A218ZTW2|A0A218ZTW2_9EURY Uncharacterized protein OS=Thermoplasmatales archaeon B_DKE GN=B2I17_03725 PE=4 SV=1 +---------------RTMKDVWKLWYRQAERNLSLVGLNN--MEYNVLRILSENNAISMVQLANLSMVTQGWITSMVDKLEERKLLERSRSTDDRRIIMIQITNAGKRLMSRAQQAHVKFLEESIKGLNETEISDLLGLLEKLKASLVE--- +>tr|A0A150WMT8|A0A150WMT8_BDEBC Uncharacterized protein OS=Bdellovibrio bacteriovorus GN=AZI86_01015 PE=4 SV=1 +----------------QMSRTMLSMKRYLIAEFEASQSPLSFEDWMNLLPLVENGSMSHRDLAHVLGKDKTTISRLVSQWIEKGYVKTEHDTEDQRIKHLTLSKEGKKLHNSLNSVVQKADRGFLKGLEQSEFDLFKKVLTKIQGSL----- +>tr|A0A1I3N0W8|A0A1I3N0W8_9SPIO DNA-binding transcriptional regulator, MarR family OS=Treponema bryantii GN=SAMN04487775_11182 PE=4 SV=1 +---------------------------FINEL--LKESQLTFADSIFLCNIAVNSGCSQEDISLNLHIDRAAVARSIRKMEECGFVLVSRDKNDSRKKILELSDNGKKLYGMVNSANEERLSALLKGCSQKNAEIFFSVLETCAKNSVD--- +>tr|F2BSJ9|F2BSJ9_STRSA MarR family transcriptional regulator OS=Streptococcus sanguinis SK1057 GN=HMPREF9394_1489 PE=4 SV=1 +-------------------------------LLNQDPEaLYRSEQGKILTVLWNsETgCATATDIALATGLANNTRTTMLKKLEEQGLVTFSQCGLDKRKKYVKLTEQGWSQKEVGHRVSQKLDAIFYKGFSEEEIRQFESYQERILANLKEK-- +>tr|R6R607|R6R607_9FIRM Transcriptional regulator MarR family OS=Firmicutes bacterium CAG:449 GN=BN661_01737 PE=4 SV=1 +-------------------------------LALKF--NLTDSTMKILYAICDiGEPTQIIDICKHTATSKQTINSALRKLEIENIIYLKFS--DRKSKNVFLTDKGKILVEKTVKKIILIENEIFNSWSKEELEVYFKLLEKYNYQFKDK-- +>tr|I2J8Z9|I2J8Z9_9STRE MarR family protein OS=Streptococcus sp. SK140 GN=HMPREF1116_1098 PE=4 SV=1 +-------------------------------LLNKEPDaQYRSEQGKILTILWKqELgCATATDIALATGLANNTLTSMVKKLEEQGLVTIQPCTQDKRKKYISLTDLGWAQKKLETVLVGNLERFSTKAFQIKKSENLRPIKRE-LSQI----- +>tr|A0A1G3YG68|A0A1G3YG68_9SPIO Uncharacterized protein OS=Treponema sp. GWC1_61_84 GN=A2001_14020 PE=4 SV=1 +-------------------------------LMKDAGLgDIGSGEGRLVYLLWRDGPMRQGELAAKAGIDKSTLALTLARMERKDLVERRQDDDDGRAVIVSVSASAALRAPSFDLVSNEMNEFFYAGLAEGEIDAFEATLKKILLNFRNE-- +>tr|A0A143WCL8|A0A143WCL8_9LACO MarR family transcriptional regulator OS=Lactobacillus oligofermentans DSM 15707 = LMG 22743 GN=LACOL_1325 PE=4 SV=1 +------------------------------------------GQGHLLSVLMEHDNLSQKELADVVHIRAASVTDLLEKMEHEGLVIRTKDEKDRRITRVSISDKGRQFLIKNNLIRHEVNEVVYGDLNDDDLEQLDMIYQKIINSLSK--- +>tr|A0A1V5RLW4|A0A1V5RLW4_9CHLR Putative HTH-type transcriptional regulator YusO OS=Chloroflexi bacterium ADurb.Bin325 GN=yusO_1 PE=4 SV=1 +---------------------------------HIRqaateQFGIGIEQFQILRHIRRGR-SSVSELADARSISRPAVSQIVDALVNKGLIVRTPDAHDRRRTRLALTAAGDALLDAVFKDTRRWMMQLFSRLDDEELQELVRGMHSLRKAQPV--- +>tr|A0A0B8NY79|A0A0B8NY79_9VIBR Uncharacterized protein OS=Vibrio ishigakensis GN=JCM19231_748 PE=4 SV=1 +-----------------------------------HKVDFSPLEHVAMSNIRELGGASQQMLVEAMQKDKTQVSRIIARLHRQDLIIKTPDPFDKRSVNLTLSDNGETLLNSLDKVESEMVENMLQGFDATEVQTLCDLLSRLNNNLK---- +>tr|A0A1C3DRE3|A0A1C3DRE3_PHODD Uncharacterized protein OS=Photobacterium damselae subsp. damselae GN=A0J46_16615 PE=4 SV=1 +-----------------LARLMMMTRSQIQQQMKRHDLPCNVESVRTLDELLNHPGINSHQLCQLTGFDKAHIARKVTEFEQKQLVYRQKDPKDKRITQLYLTAEGMDVARCCITLRNQTVLELMAGIQPNALESLNIFLESFKAENQK--- +>tr|A0A133KSD5|A0A133KSD5_BACCO Transcriptional regulator, MarR family OS=Bacillus coagulans GN=HMPREF3213_01746 PE=4 SV=1 +----------------------------------LAQFGLSYSLWQVTFYVRNFGPCTLVEICKYYQVEKPNVTRIVQKLEEQGIVEQIPGK-DRREKVIRMTERGENLYRQCRAEITGLEQQAMKGIPEAEQEMVFELLPQIRDNLDH--- +>tr|A0A179SMR5|A0A179SMR5_9BACI MarR family transcriptional regulator OS=Bacillus litoralis GN=A6K24_10325 PE=4 SV=1 +----------------------------------LQKHDLYSSQWSILYCLKINGPMTQSDIWRYLVVEAPTVTRTLVKLEESGWVKRTQGS-DKRERLVSLTDKAIQHLPAVEDEVKSFEQRMVKSLSNEEKDYFFHLLNKLGTTSLE--- +>tr|A0A0M0ES55|A0A0M0ES55_9BACI Uncharacterized protein OS=Bacillus butanolivorans GN=AKG34_03605 PE=4 SV=1 +----------------------------------ITALEIYHNQWTILNYLKNCGYSTIPDICNYLDVDSVIITRSVNSMEQNTMIKQVPGK-DEQEKRIELTPKGKEVHTKCLKIAEKIEGKALDGITEEEQDLFFQTVLKILNNIRN--- +>tr|A0A0P7N220|A0A0P7N220_9BACI MarR family transcriptional regulator OS=Lysinibacillus sp. ZYM-1 GN=AO843_04610 PE=4 SV=1 +----------------------------------LEPYQLYSSQWAVLRFLKDKGPHSFVDIANFMSIEKPSVTKLVHKLLELGYVETMAGK-DKREKLVHLSAYGEELVQEIKSHLKPFFEHALAGVAQQDIEIATQVFARIYMNINQ--- +>tr|E0RIX1|E0RIX1_PAEP6 Transcriptional regulator OS=Paenibacillus polymyxa (strain E681) GN=PPE_02119 PE=4 SV=1 +-------------------------RREIETA--LRPLGLTSPQSQTLYILAMSPGVTNTDLEKLLLIDKSSVTSLVNGIVKKNWAVRKSHPEDARMKQIYLTEEGLEIHKIAERTIEAIKSSVGETLSVGESETLRGLLKKILHDYR---- +>tr|G5HTX4|G5HTX4_9FIRM Uncharacterized protein OS=[Clostridium] citroniae WAL-17108 GN=HMPREF9469_06036 PE=4 SV=1 +-------------------------TYYRNVK--MHALGLTSVQGDAIRAILHNPGITASRLQDLLGLSQSTTAGIVARLEHKGFLSKINNKLDGRELFLTPTQRCLNLEEQLKETALETQRLLIKGMTDEEQFEFNRLLELALTNMS---- +>tr|F9TAZ0|F9TAZ0_9VIBR MarR family transcriptional regulator OS=Vibrio tubiashii ATCC 19109 GN=IX91_23340 PE=4 SV=1 +---------------------------YVSHLL--EKCDVSFSQLPFVTCLYKNPGITQEALSRKVEVDKAMCSRVLKQLEQKGLVARKISPQDARAKLIYPTDQLIAKKRDLLRIIKEWNDILTQGLTNEEIETVKRVNQKMIENVQRK-- +>tr|A0A0D4E1D6|A0A0D4E1D6_9ACTN MarR family transcriptional regulator OS=Streptomyces lydicus GN=T261_8005 PE=4 SV=2 +---------------------------IAGQLL--RRVGLHLGQELVMMHLWELGPQRQTDLVRLIDSDAATMTRSIKRLENAGFVRRRPCPDDKRAVIIEPTAASQALRREVERIWAELEGASTGDLTPDQQAETLNTLRRIEDSLART-- +>tr|A0A1X2AX62|A0A1X2AX62_MYCPR Uncharacterized protein OS=Mycobacterium peregrinum GN=AWC21_20580 PE=4 SV=1 +---------------------------WGSEML--LELGLHPGQELILMQLYDRDGQTQSELQQALGVDHSTISRAIKRMQLSELVARAASDNDRRAKEVWLTDKGLALRKPLERLWTSLEQCAIEAVPPSRRAEFARSVAKLEQTYTSA-- +>tr|A0A1V5HUY4|A0A1V5HUY4_9SPIR MarR family protein OS=Spirochaetes bacterium ADurb.BinA120 GN=BWY96_02560 PE=4 SV=1 +---------------------------FIEREMErRGIEGMAPSFGDVFMIVAARGPLPMKEIARLTYKDKSTITGVVRALEKAGYLSRSGDPADGRAALVSITPEAVKITPALRMASTSMNERLLDGLSERDCRTLFRLLGRLGANLKSA-- +>tr|A0A0Q5TBQ7|A0A0Q5TBQ7_9BACT MarR family transcriptional regulator OS=Dyadobacter sp. Leaf189 GN=ASG33_01800 PE=4 SV=1 +------------------------------AQLVQEGIPVLAEQLPILMVVYfqE-HAMTQQDIANVLQKDKAGIQRSVQTLHKDGFLKIESDIEDKRKNMVTLTASGKFVCERIQALVIAFDNQVMEHFTEDERKTFMGFLDRVTAVIE---- +>tr|A0A0R1Y293|A0A0R1Y293_9LACO Uncharacterized protein OS=Lactobacillus pontis DSM 8475 GN=FD34_GL000153 PE=4 SV=1 +------------------------------------QPSNFRGQGRIIDLIAHHEGCAQRELAVLAGVKPGSLTEVLERLERNGYVSRQRDERDRRVIRVALTTRGRTFHADLVAKRTAFARRLLTDVSPKEREQF----IRVVDKMQT--- +>tr|A0A089LX40|A0A089LX40_9BACL MarR family transcriptional regulator OS=Paenibacillus stellifer GN=PSTEL_12650 PE=4 SV=1 +------------------------------------AEGLTSDQFTILRLIHGQEKCTSTFLAEACCVGKSSITAIVNRLVEAGLIDRTRDESDRRQVYLTISSLGSQVFDEANQNVSEILTPYLLHFDEDQIEQFISMFEKLADLMKE--- +>tr|A0A0G0LZP3|A0A0G0LZP3_9BACT Transcriptional regulator, MarR family OS=Candidatus Daviesbacteria bacterium GW2011_GWA2_38_24 GN=US86_C0003G0097 PE=4 SV=1 +------------------------------------QNHITHSQWFVLKVIDHLENPRVKDVSEALSMSSSATTQLVEPLVQAGFVLRKEDPKDRRLVQLQLSLKGKKQIAAKKEECIAEMGMIFEGLTDKELEEF----VRLHKKITL--- +>tr|A0A1W6VX04|A0A1W6VX04_GEOTD HTH-type transcriptional regulator MhqR OS=Geobacillus thermodenitrificans GN=mhqR PE=4 SV=1 +------------------------------------RVGLNLTDYKVLGIIPF-EGLTAGEIASITGLSTGMVTTVVDRLEKKNFVYRDRDPDDRRKVIIKANFEKIgSELGPYFQSFGQEIGKVVSKYSPAEMEVINDYIRKTTEVFKR--- +>tr|A0A218ZM79|A0A218ZM79_9EURY Uncharacterized protein OS=Cuniculiplasma sp. C_DKE GN=B2I18_04105 PE=4 SV=1 +------------------------------------KENLSFTGFFVLSTLSKGGRMKSSDLALRLGVTKPSISHIIDNLESKGLVIRQYGMDDRRAIYIDLSVKGKLMLEKLYNVKSMALKAMG-EIDQQTIEGFlqfVNMLAKNVHEIRE--- +>tr|A0A1W9ZB32|A0A1W9ZB32_9MYCO Uncharacterized protein OS=Mycobacterium arosiense ATCC BAA-1401 = DSM 45069 GN=BST14_20465 PE=4 SV=1 +----------------------------------FSDSGLNLAEATVLAHLV-DGALTQSELARRVGTSRARIGGLIDSLEPRGAVRRDGHPTDRRVWLVNLTDKGHAMWESTVAADRTLRKHLRKGTTAQQRERLDEVLTLIQENALAFL- +>tr|A0A0R1GMA6|A0A0R1GMA6_9LACO Uncharacterized protein OS=Lactobacillus parabrevis ATCC 53295 GN=FD07_GL001510 PE=4 SV=1 +----------------------------------LAPMGINRSAWMALYYIDQHQQIRQRDLAELVGITGPSMVKVVNQLNTADLITVAVSAQDHRARLLALTPAGTALLTKSIPLAEAFRAQVTAGIPQDDLDTLDRVMEQMMANAND--- +>tr|W6T422|W6T422_9LACO Uncharacterized protein OS=Lactobacillus fabifermentans T30PCM01 GN=LFAB_16475 PE=4 SV=1 +----------------------LKFEAARNAFYEQ--YGMTGSQADVLEFLKNQPAQtaPIGDIVGALQVSYATTSGLINRLEKKELVERIVNPDDQRSFLITLSDKTTVAeiFAAENAALSVVDQQLTRDFTPAEFVTFVRLLRQLNHN------ +>tr|A0A0R2B6X6|A0A0R2B6X6_9LACO Uncharacterized protein OS=Lactobacillus brantae DSM 23927 GN=FC34_GL001024 PE=4 SV=1 +----------------------HQLKYQLNQALLQ--EDLTVQQWALLQQLMLERPLTAVQLANRLDMDKPTVSGIVKRLVEKDFLTKQANPTDQRSQLLNLTTAGQTAAITGQGISNQILDAIIAPLSTEDQQLLNQLLGKLIPTKE---- +>tr|A0A1F3RVU5|A0A1F3RVU5_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium GWA1_52_35 GN=A2X97_16560 PE=4 SV=1 +----------------------LGMQIqQINQKM-EHEIGVSLTQWSLLRCMVDNPTISALDLAQELGVQPSTLTQILKRLERKKYIFVTKDPLDARRKLLSLTRAGNSTLLEANRTIAALEKhvKFSNTAVREISRGLTHLL------------ +>tr|A0A1Q4B8X8|A0A1Q4B8X8_9RHIZ Uncharacterized protein OS=Rhizobiales bacterium 62-17 GN=BGP04_19380 PE=4 SV=1 +-------------------------------------HRITPLQFTFLWILSIEENLSQVELAQRAGITRASATDDIEALKSRKLIRGRRDATDKRKIILSMTAAGNDMVTRLADHAAVTNTTARGELSKQAYRQLFDLLAQVTSNLNAAS- +>tr|A0A1Z5IHV5|A0A1Z5IHV5_9LACO MarR family transcriptional regulator OS=Lactobacillus silagei JCM 19001 GN=marR_7 PE=4 SV=1 +----------------------------------LRHVGIYPGQENILVELLNYGELSQNDLVKRIVVNHSTIAKSVSRLVSAGLATTTKSTADGRITLVSLTSHGQLVANQVKQILDHAELTLLKGLSKSDQQTFISLASQIGSNLA---- +>tr|A0A090AAK6|A0A090AAK6_9GAMM MarR family transcriptional regulator OS=Thioploca ingrica GN=THII_0231 PE=4 SV=1 +----RDFVSQEETVLLSFMHTWQHLDRLGKLFF--PRFGLSDAQFNVLMVLwdYRETGMRQHELASLLMVNRASVGGVIDRMERQVLVQRQRDPVDRRSNYVHITAAGIALLEKIKPVYYALFPPAFANLNSHQQQEFFKLLEQFRQGILQV-- +>tr|A0A0B6WZ76|A0A0B6WZ76_9BACT Transcriptional regulator OS=Pyrinomonas methylaliphatogenes GN=PYK22_01476 PE=4 SV=1 +----KEFHRPSVELLLNLIYTYDVIRSRVAKRI--EAYGLSPAAFNALMIIshYGESGCPMCEIGDLLLVSRPNVTGLIDSLACKGLVERVEKEGDRRFRLVRLTRAGERLLDELLPSHYANVRAMFAGMSDKEKAILSKLLVKLRHEVLRS-- +>tr|A0A1F5UCM1|A0A1F5UCM1_9BACT Uncharacterized protein OS=Candidatus Firestonebacteria bacterium GWA2_43_8 GN=A2044_07410 PE=4 SV=1 +----REIETKEHECVMSIMYTSTLLYKIAYKYF--SGFNITESQFNSLMQLkySEKEGMSQIQLSRRLLVNKADVTGLVDRMEKAKLVERLSAPSDRRVKIIKITKKGLETVKTMESGYFNYVNKVMGGLGKKEIENMVQGLQSIRKNAQGV-- +>tr|D6U0F1|D6U0F1_9CHLR Transcriptional regulator, MarR family OS=Ktedonobacter racemifer DSM 44963 GN=Krac_3086 PE=4 SV=1 +-----------------------------SDRQFFASYGVNTRRYWALQHLDEQQGCSMVELSRVLFTDKSNVTGIVDRLESQQLVERKTDPGDRRVILITLTAQGRQLRDHLHGLHEAHICKQLNIVDIEQLAHVRDCLRAFSENIEL--- +>tr|A0A1M3JXJ3|A0A1M3JXJ3_9CHLR Uncharacterized protein OS=Chloroflexi bacterium 44-23 GN=BGO78_09005 PE=4 SV=1 +-----------------------------GDRRFFQGFGLSQARFYALLHVQKDPGISLTELSRRLLCTKGNTTRILASLTEGGLLSRTVDPQDQRAYHLEISARGQGLFDQVRAAYQHFNQERFTALTDRQKRMLLDQLQILNDDLVR--- +>tr|A0A101VE96|A0A101VE96_9SPHN Uncharacterized protein OS=Sphingomonadales bacterium BRH_c42 GN=APF82_09245 PE=4 SV=1 +-----------------------------------WHTGMSAREWRVLGMLGIVGs-RMPSELADLTGMDRATISRATSRLVHLGYVSRLPNQADNRSQTIELTPAGEAYCQAIVPRMEHSGEECRSLFSAGEFALFIEFLDRMDAAIAD--- +>tr|A5V6K7|A5V6K7_SPHWW Transcriptional regulator, MarR family OS=Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273) GN=Swit_1560 PE=4 SV=1 +---------------------------------HLKKNDFTEAQWRVLRAVAEGNCNDQRSVARAALLHPPSVTRILKELAQRGLVERGANETDGRRQIIVATARAREILDEATETNREIVRRYRATFGAERFDRMVSELRDF--------- +>tr|V6HQ14|V6HQ14_9LEPT MarR family protein OS=Leptospira inadai serovar Lyme str. 10 GN=LEP1GSC047_0610 PE=4 SV=1 +------------------SRTRDRIQKFLGRELEKQGIqDIAPAHAGVLFVLSKNGAMRMSELATILDRTNSTATALLDKMEEFGYVIRTKLDPDERVTTADLTEKGKRSVEKVIKASKITLNKLYKGLDETEKAEFVRLLSKIHANFEI--- +>tr|A0A1V4E560|A0A1V4E560_9ACTN Uncharacterized protein OS=Microbispora sp. GKU 823 GN=B1L11_29095 PE=4 SV=1 +------------------DRLREATDRV-AAALATVGNwmfapatrrrimaasGLElsLGDYTLLAQISLHAPVRLSVLAEQMEVDKSTLSPPAKRLESRGFIERQPDPADARAKLVSVTREGKLAIRRLWKARTAAVAALMEGWEPSDIEHLADGLAAFAEAIKKG-- +>tr|A0A231P1I2|A0A231P1I2_9DELT MarR family transcriptional regulator OS=Desulfovibrio sp. MES5 GN=BCS36_09910 PE=4 SV=1 +------------------AAIREQANTLILSSLSERGItDILPAHGAVLNALFKQSPMQMNELAEHIGRKKNTVTGLIATLEDRGYCRRESDPQDARAQLVFLSEKGEAMRQVQDEVSVELLQKIWTGIETQKQIECIQCLETILQNLTNN-- +>tr|R7BHQ2|R7BHQ2_9FIRM Transcriptional regulator MarR family OS=Firmicutes bacterium CAG:882 GN=BN803_02038 PE=4 SV=1 +-----------------LGFEIKKMDNIIFRQLKKKlvdaGfDEVTVMHGHILGYLCRHKDKDlyQKDIGEAFGIGKSSVTNILQLMEKKGYLVCRTDDNDGRCKKIVLTQKGEETHAATVKVIDMLHEELEQNVTEEEKRIFLNVIEKMKKNIN---- +>tr|A0A1C5NDN8|A0A1C5NDN8_9FIRM Homoprotocatechuate degradation operon regulator, HpaR OS=uncultured Blautia sp. GN=SAMEA3545244_00965 PE=4 SV=1 +-----------------IGRELHTLDMMIGRLVNAyQskvdEkAGINRMQGWIIGYLYRHSDEDvfQKDLEAEFQMARSTASGILQSMEKKQLIIRESIPRDARLKRLVLTPKGMEFQMEIIDNFARIQKALSADIPEKKLEEFYETADMIRENVV---- +>tr|A0A242LEB8|A0A242LEB8_9ENTE Uncharacterized protein OS=Enterococcus termitis GN=A5881_002559 PE=4 SV=1 +-----------------IGLKIRILANELNRKAAEIlkedDgEASSSIQMRILNFIHRrnSQQVPvyQKDIEQEFDIRRSTATGVLQTMEKRLFIERKCCEKDNRYKTIILTELGQQKVKENIVKLHKFDELLVQGISENDLTIFFKLMEKLSENSK---- +>tr|R9T4T1|R9T4T1_9EURY Transcriptional regulator OS=Candidatus Methanomassiliicoccus intestinalis Issoire-Mx1 GN=MMINT_05730 PE=4 SV=1 +---------------------------------TLKQYNLKACYLPYLVTLFQKGNATMKELTEQTGTDKSNTTRMISELRERGIVADDRKNKNSKKYNVHLTEQGRELVIKSKNEFESSIDVLFSDLSAEELSTLIKIMKKTQD------- +>tr|R6TWS4|R6TWS4_9FIRM Uncharacterized protein OS=Eubacterium rectale CAG:36 GN=BN626_01523 PE=4 SV=1 +-------FTPDKYLGHKINRISRSIDRYFDRKRcsKTEC--IPRSQGMMIGYIMDNQGqnIFQKDIEAKFHLSGATVTNMLKSLEKNGYIVRTPMENDARLKRIELTQKALDHENRVRENIMVIEEAMHEGFSKEEFNMMLGFLDRVIDNMEK--- +>tr|R6Z3M4|R6Z3M4_9FIRM Uncharacterized protein OS=Roseburia sp. CAG:309 GN=BN600_01736 PE=4 SV=1 +-------VIREANPVKLIMFINQIHRRKIEKLLDGTG--LHRAQHRMLMTLSDCPVTSQVELANILEVSAATVAVSLKKLEKGGYIQKTQQEQDSRVRFVELTEKGRGVVEESKEIFHQMDAKLLEGFDKEQLEVLQSLLGQMYRNAKN--- +>tr|A6LJB1|A6LJB1_THEM4 Transcriptional regulator, MarR family OS=Thermosipho melanesiensis (strain DSM 12029 / CIP 104789 / BI429) GN=Tmel_0135 PE=4 S +-------FSL---AFLLFSEIEKLKFQILRSEMEKYK--LHPGQIPMFFIINKFPGITQKEIAEHMMVNTSTVAIMLKRLEKAGFVKKEIDENDRRYFHVYLTDKAKGIHDKLIKKVKEFEKMCFSGLSDLEMKELENLLKKIVNNLEA--- +>tr|V8C438|V8C438_9FIRM Uncharacterized protein OS=Ruminococcus lactaris CC59_002D GN=HMPREF1202_01584 PE=4 SV=1 +-------LGM---TAHKIG-------KLAQTMYAEYD--LNKSQSMILFQLHRDGRISQKELAQKLNVSAPSITSMIQKMEKSGYIVRNVDEKDQRMMRLDLTEKGQACIEHVKAIAEKMDEIAFTGISPEEKMLLRRILFQICENVEK--- +>tr|A0A1H6S7P6|A0A1H6S7P6_9LACO DNA-binding transcriptional regulator, MarR family OS=Sharpea azabuensis GN=SAMN04487834_10145 PE=4 SV=1 +-------FAN----FRRIGIAYR---NAASRQLNDMH--ITHEQCALL-YLIEQSDMTQKEIAQKLKISEATLSGRVKRLEKMHYIERVQDQNDKRKYDLFITPSGKKALDEAKSIVDRLSKQCFEGFDDQDFALLMSLFQRVYKNLEK--- +>tr|A0A1M4M9F8|A0A1M4M9F8_9FIRM MarR family transcriptional regulator OS=Proteiniborus sp. DW1 GN=DW1_2743 PE=4 SV=1 +--------MIETDVAMQLRETYQKITQILQHKVDEYG--LTFGLLFLTMLIDKKPDASQKELAKIMRFTEGAMSGAVKRLINLKMIEQVPLESDMRYNRLVVTELGKSMIDDYRDYVVKIYQDMFKGFSQEELSKLNEVLAKLNHNLTN--- +>tr|A0A1Y4P1A0|A0A1Y4P1A0_CLOSC Uncharacterized protein OS=Clostridium saccharolyticum GN=B5F06_06290 PE=4 SV=1 +-------KGLLGRVMEKCAVTARLHQNYLRREMGKTG--ISKSQRQLLLYIEKNPGATQREIAARRNVSTASVAVAVKKLEKEGYLIKDTDRTDSRRSCLRLTCGGQKVADESKRLFEYTEASMFSGFSEEEILQFENFLNRIIKNGES--- +>tr|A0A1Q6CJ62|A0A1Q6CJ62_9GAMM Uncharacterized protein OS=Thalassotalea sp. PP2-459 GN=BI291_11520 PE=4 SV=1 +-----------------------------------GEFDLSRQQWRVLAILATHAPINAKSIGTLADLEKMPTSRAIKGLLAQQLIIRVNSQTDKRAQLLSLSAQGDLLFKQLVPLVSQQEEALLSVLSTQEKQCLATVFEKLAKQ------ +>tr|A0A239DQX7|A0A239DQX7_9RHOB DNA-binding transcriptional regulator, MarR family OS=Antarctobacter heliothermus GN=SAMN04488078_1011115 PE=4 SV=1 +-----------------------------------AHAGITITQWRIIAVLGDTGRCTSAQLSRLTDMDKGLISRSVKSLAAERMITVTRDTSDNRALHLDLTAKGRATFEHTIPRMRSRQMGLRACLDEAEFDALMRACEKLEKA------ +>tr|D6XXH6|D6XXH6_BACIE Transcriptional regulator, MarR family OS=Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10) GN=Bsel_0497 PE=4 +---------------------ITLTAHLLQNEHNraLGDLDVTPAQSKALYLLNRFGSQSQTELQDRMYIKGSTMNGIIDSLQKKHLIHKEDSKTDRRVKVIWLTEEGERLEREIWEMLGALEARLMAGISPKRKQELIRTIEQLQDNLKT--- +>tr|U4KLC6|U4KLC6_ACHPJ Transcriptional regulator, MarR family OS=Acholeplasma palmae (strain ATCC 49389 / J233) GN=BN85410210 PE=4 SV=1 +----------------------------------NQKINLSNGQARVLRyiYENtkDDKEVFQKDILEAFSIRGASVNGLIEGLIKLDCIKREIDMSDKRKKKLKMTSNGNLIVLKSYEIILEFENSLKSSLQVEELEQLEKILLKLENEI----- +>tr|R9WI20|R9WI20_LACRE Transcriptional regulator, MarR family OS=Lactobacillus reuteri I5007 GN=LRI_0021 PE=4 SV=1 +----------------------------------APELDVTPQQAHTLFYIEKHAGLIQRELGDHFHLRNASVTSMVKNLERDGYIIRKADQESARIKRIFLTKKGEEKTNEVKEIFDQAYLQIIARLDERDINAIVKGMTNINNNL----- +>tr|C5QMM2|C5QMM2_9STAP Transcriptional regulator, MarR family OS=Staphylococcus caprae M23864:W1 GN=HMPREF0793_0478 PE=4 SV=1 +----------------------------------LDDFGITQEQSHTLGyiYRHQEEGMTQKTLLEAFDRKGSTVSSTLKILESKGLIYRKVNPKDTRSKLLKLTDEGITLVESFIKIFDEIEENMLKDFTDNDKEKLREYFDRMMNNL----- +>tr|A0A177XIV4|A0A177XIV4_9BACL MarR family transcriptional regulator OS=Brevibacillus sp. SKDU10 GN=AYJ08_17850 PE=4 SV=1 +-------------------------------------EGITSAQYNVLELVQTQGPKTTNELASALGITVSGISKLTKKLLQKGLIEQQRSQADRRYYHIVLTEAGVDFLRKAEKSRKEIIQLIGKALSKEEIEAFSRICSKLNTYL----- +>tr|A0A1F9ZT83|A0A1F9ZT83_9FIRM Uncharacterized protein OS=Firmicutes bacterium GWF2_51_9 GN=A2Y20_02805 PE=4 SV=1 +---------------------------------------LYPGQPRLLFFIDRQPGCTVSQLVEETGQTKEAISVSVKRLEEAGYLHKEINPMDKREKFLYLSEKGKTTADVIHNEFHRINEAMFEPLNEEEKEHLDEMFRKMSDRLHA--- +>tr|W1RZI9|W1RZI9_9SPHN MarR family transcriptional regulator OS=Sphingobium sp. C100 GN=C100_17990 PE=4 SV=1 +-----------------------RFDQSVEQ------MGVSRAKFAVIALVSRKPGVSQRAIAERLQVTEVTAGRLVERLCADGFLERRGNPNNRRTYFVHLTAAAQPLLDELSVVAAAQEKQTFRGFSTDELDQLEQFLARISANIA---- +>tr|A0A1I9YEN4|A0A1I9YEN4_9BURK Uncharacterized protein OS=Paraburkholderia sprentiae WSM5005 GN=BJG93_04720 PE=4 SV=1 +----------------------------------TKCYNMTSIQFGALQVIADRPGIDQISLCQATDIDRTSIMRVLERLKSEDLITKEASTEDRRVSSISITEAGRERIDSLVARAEASQVRLLAPLTSGERQEFMRIMIKL--------- +>tr|A0A151Z0T5|A0A151Z0T5_9BACL Uncharacterized protein OS=Thermoactinomyces sp. AS95 GN=AYX07_02500 PE=4 SV=1 +----------------KQYAITRRIGQHITTALSEIGL--TRAQFHILNYIGSSDRCRATDIANMMEVKPSAVTLMIDRLEAHQWVRRSQDAFDRRVVVIELTEEGKNILSKAKKISEEVVKHYLSNLSQDDLIRLLEIYEKLERIVND--- +>tr|A0A0W8E7V8|A0A0W8E7V8_9ZZZZ Organic hydroperoxide resistance transcriptional regulator OS=hydrocarbon metagenome GN=ASZ90_017850 PE=4 SV=1 +----------------NMRAAMKKIDRLFSNKLEDIGI--SIPQSFILFCLQEENGLTLKEIGSRTLIDSSSMTVLVDKLEKDQLVKRQLDSQDRRAIRVFITEAGMEMGEKISVVISNLNTLLFDLLGEGNQKEFIHGLNNIVNGVED--- +>tr|C1ADG5|C1ADG5_GEMAT MarR family transcriptional regulator OS=Gemmatimonas aurantiaca (strain T-27 / DSM 14586 / JCM 11422 / NBRC 100505) GN=GAU_350 +----------PTSSGPLVDVGelhrtLVNVLRLLRD--VDRESGVSPSRLSVLSVLVFVGPMSQAELARIEGVSAPSMSLLVRELETDGWVERTPDPVDARRTIVSASKGGRDLMLRSQRRRLDWLSAAISRLPVESQRVLAGCsthLDALIAALRETY- +>tr|A0A0P0Z6H2|A0A0P0Z6H2_9RHIZ MarR family transcriptional regulator OS=Aureimonas sp. AU22 PE=4 SV=1 +----------LTTPGHLVSLAARGFARLSEA--RLKPLGFGIGHLPVLVALRDGEASTQRELARFARIEQPPMAQMLRRMERDGLISRTPDPNDGRSQRVVLTDAALARLPQAITVLFQGNRDALEGFTDGEAEQFLNFLSRLLANLDGLT- +>tr|A0A1X2AZK6|A0A1X2AZK6_MYCPR MarR family transcriptional regulator OS=Mycobacterium peregrinum GN=AWC21_19760 PE=4 SV=1 +----------ESGAGYLVKRVQQSLRRNCDA--ALRSTGLSMAQYTALRALADHPQASAAELARLCFVTRQSLQDVLSGLRTEGLVEESPGPQRGRARALQLTAAGRRRLGQAHSAVIHVEQDMLNGLSGKEQKELATMLLRCAENLEAAA- +>tr|A0A1F3P1P7|A0A1F3P1P7_9BACT Uncharacterized protein OS=Bacteroidetes bacterium RIFCSPLOWO2_12_FULL_37_12 GN=A3G23_00480 PE=4 SV=1 +----------------------------------LKNHFVTDIHYNILRILRGQYPSALG-PTLIRQRmiRRAhQIPMqFFIALARKGWIKGIKVMQHGIQQEYVITKEGLELLDKIDPVTKEVEAKSMKNLTPVEAEQLSKLLDKLR-------- +>tr|A0A1R1M272|A0A1R1M272_9GAMM Uncharacterized protein OS=Motiliproteus sp. MSK22-1 GN=BGP75_12915 PE=4 SV=1 +----------------------------------LDPLDLTLQQLKILSIIYRSSENKAT-VNQIKQQmiDPSsNVSRLLNKLMDKGLIEKIRNREDQRVVHIHISKAGIRMMCTGKQAMDQGMS-VLGKLDLEELKQLDKLMNKLR-------- +>tr|Q11JD9|Q11JD9_CHESB Transcriptional regulator, MarR family OS=Chelativorans sp. (strain BNC1) GN=Meso_1089 PE=4 SV=1 +----------------------------------VGpASLITPVQAGVLILIAENPGVMQARLLKVLDVESATLVKSITRLAEFGYIERVRNPDDKRAFHLYLTPSGQEALKFVAAKMREREEGLRTSIDPAEYEVFRKVLLQLI-------- +>tr|A0A127MDI5|A0A127MDI5_9SPHN MarR family transcriptional regulator OS=Sphingorhabdus sp. M41 GN=AZE99_04750 PE=4 SV=1 +----------------------------------FSDLDLTQKQVSVLWLVDDHPDIAQTGLAKRMRMDRATTMAIINRLQKRGYLVRGKSKTDGRKQTLNLTDEGRTALASAKVAIQEHENWLKSRFKQKEVDLLIELLSKIH-------- +>tr|A0A1M4V417|A0A1M4V417_9GAMM DNA-binding transcriptional regulator, MarR family OS=Marinomonas polaris DSM 16579 GN=SAMN02745753_00553 PE=4 SV=1 +----------------------------------CSDLGISPGLFAIIAIVERNPGLTQTAVAQALGNDRSAMVAAVDKLEKMDILERRPAINDRRSYALFMTKKGEKFFLTLSERVMEHEQIMAARLEGDNELDwLLKTLDTLS-------- +>tr|A0A084K0B0|A0A084K0B0_9FLAO Transcriptional regulator OS=Nonlabens ulvanivorans GN=IL45_00810 PE=4 SV=1 +-----------------------EMTESVSEIV--KKEGLTIQQFNVLRILRGRKGKAA-NLQDVSRKMIhsnSNTTRVIDKLISKDYVERKQCPSDRRQIELKITKKGLQVLENLDADIDARELSLINNLDEDQVKQVLEFLSK---------- +>tr|A0A1J0LLY0|A0A1J0LLY0_9FLAO Uncharacterized protein OS=Flavobacteriaceae bacterium UJ101 GN=UJ101_01754 PE=4 SV=1 +-----------------------EIEQAIKKAL--KsSCGITHTQLNILSILEQEYPNPV-NSNFIKNNLIisssPDLTRLIDRLVKKELVERYTCPTNRREVNIVINPKGIETYKKAHKHAKQvTKNYFSEDLTEEEARTLYKILSK---------- +>tr|A0A1B9K957|A0A1B9K957_9GAMM Uncharacterized protein OS=Gilliamella apicola GN=A9G13_06475 PE=4 SV=1 +-----------------------ALLENLNEIY--IKHQLDDKLFAVLLVVQWHHPEGV-KPSQISELTNfsrVQITRFVDALVANDLVARKQVPNDRRSHWLILTDKGSNFFQQQMPPLEKKVVAAWQVITAEERQQLRTILHK---------- +>tr|A0A1F1WYC0|A0A1F1WYC0_9CORY Uncharacterized protein OS=Corynebacterium sp. HMSC05H05 GN=HMPREF3151_11130 PE=4 SV=1 +-------------------------------------RDTFSGQGRVLKLLALNNPVAQKELAYVLGIRSQSLAELLTKMEAKGLVSREPNPADRRTSIVSLTEDGQVAARELERSTDDEFDPFSTLSDTErteLDTILRKLIAGVEAEMSPS-- +>tr|A0A0F5PGR5|A0A0F5PGR5_9SPHN Uncharacterized protein OS=Sphingomonas sp. SRS2 GN=WP12_01960 PE=4 SV=1 +---------------------------------ALRPTGTDRARWRLLLTLWQGKPLSIKEIVEITNFNQSTVSKIIDRMKRDDWVNTESRRSDSRFTDISLTERGHQVLIELTKVASREYWRSLDGVSESDLQTTLNTLHKIMKNIAA--- +>tr|A0A1S2FNH4|A0A1S2FNH4_ACIBA MarR family transcriptional regulator (Fragment) OS=Acinetobacter baumannii GN=A7N09_34700 PE=4 SV=1 +---------------------------------SIKKLGIDNTRRKIILSTNALGEASITDIANLSTLKLTTATKAVYRLVEDGIVEVYSSTSDERISMVKLTAKGIELVEQINQISVVTLAGILNAFSEDELHNLNTQLKKLFDLMPS--- +>tr|A0A1B3M317|A0A1B3M317_9BURK Winged helix DNA-binding domain protein OS=Hydrogenophaga sp. RAC07 GN=BSY239_4416 PE=4 SV=1 +---------------------------------------MRTAEHEILMNLRRESGLSQQALAARCFTAKSHISHLLGEMASRGWVKRESDPADGRVKRLVLTPSGSRMAERTAAVQVDVVALMTAGATPDDLANVQAAMSEASRRL----- +>tr|V4PQP0|V4PQP0_9CAUL Uncharacterized protein OS=Asticcacaulis sp. AC460 GN=ABAC460_18095 PE=4 SV=1 +----------------------------------LRPMGINLTQMSLLNHFSWQPDraQSITELTDVMAINQPGVTKAIAALADRGLVEKIDDAEDARVKRVKITPAGLEALGQARQAAWPPVEAAFGSLDDEELAAFTSHLVKMKASL----- +>tr|N9PV99|N9PV99_9GAMM Uncharacterized protein OS=Acinetobacter sp. NIPH 2168 GN=F892_00818 PE=4 SV=1 +----------------------------------LSDYGLTPPQFTILKIVSVYSGCSNAEIARYASLTPQTVNLMINKLEKLEFVIKSAHPHNKKVQCIEITKDGLHILEQSSDAIEQLEAQLEHHFSSEEIYTLRKWFAFIQK------- +>tr|N8XMF2|N8XMF2_9GAMM Uncharacterized protein OS=Acinetobacter sp. CIP 56.2 GN=F966_03287 PE=4 SV=1 +----------------------------------LLELKVTSAQFAILSIIYNCPGLSNAEIARLSLLTPQTVNQIISKLESQNLLIKKKHPTNKKVQQLELTESGVECFHKCNVIIEDLEVEIKDQMPPDIESGVREWLKNIIEN------ +>tr|A0A0N0RD77|A0A0N0RD77_9CHLR Transcriptional regulator OS=Levilinea saccharolytica GN=ADN01_10040 PE=4 SV=1 +------------------QRAH-QMLRSARKIINeeLRPLNLSSAEGNILLHLFTQgqGELGQEQLVEQLDISKPAVSRALDSLEQKGYVLRQEDPSDRRVHRVRLTERARTVGPQIERAYNQLYAAAMQGISQEELAAFLHLFTRMSENFTRA-- +>tr|A0A087D9V7|A0A087D9V7_9BIFI Transcriptional regulator OS=Bifidobacterium saguini DSM 23967 GN=BISA_0706 PE=4 SV=1 +------------------DELHFLLLRAfnhSNRRIDeaIRRIGLLPGQPKIIECLAEQDGRTAKEICAECILDKSTMTGLLNRMEQRGLVRREVHETDKRSYRVFLTESGLDYATRIAAIMQQADELAMQGMSETERKTLREGLRHVIANIEQE-- +>tr|F4GQ51|F4GQ51_PUSST MarR family transcriptional regulator OS=Pusillimonas sp. (strain T7-7) GN=PT7_0834 PE=4 SV=1 +----------------------------------LDNWSITPPRFSAMIIIDKNADMKLTELAAAMGIARSGAVEVVNSLEKLGFVSRTDSTVDKRAHALALSSEGKKALSSITQAIQAHDARISTRLTADEQAELRRLLGLLG-------- +>tr|R5ZBP3|R5ZBP3_9FIRM Transcriptional regulator MarR family OS=Firmicutes bacterium CAG:536 GN=BN700_00482 PE=4 SV=1 +---------------------------------------------------------TPKHIYELQMFTRGHISQSMKRLGKAGYLRMEVDKHDHRVFHCFVTEYASEILAQVDEAMESIHRKLFRQISPEQMTQFLEIAQVINRNIIEE-- +>tr|K2EV21|K2EV21_9ZZZZ Transcriptional regulator OS=groundwater metagenome GN=marR PE=4 SV=1 +------------------------------------EdNATTLLQIEALKYIHANSSVTVGSLARELDMSLSSTTQLTNRLADKGWVSREIDQNDRRVTGLSLTKLGLTQIKGLINPMISSNYKVLASIPEKDLKEMIRIFGNIADSQR---- +>tr|A0A1Q3Y4U2|A0A1Q3Y4U2_9BURK Uncharacterized protein OS=Burkholderiales bacterium 67-32 GN=BGO71_31155 PE=4 SV=1 +-----------------LHRAAHIIAATFGDELKADDIPL--SVWRVLATLNDRDHQSLSELASHTGAELSYLSRTVAQAEERGFVVRSAQPGDKRATSVRVTPAGRAVVRKFSPLTQTLQKQWLADIPDADVEATFRTLRAVYQNAV---- +>tr|A0A1W1WDD3|A0A1W1WDD3_SULTA DNA-binding transcriptional regulator, MarR family OS=Sulfobacillus thermosulfidooxidans (strain DSM 9293 / VKM B-1269 / AT-1) +----------------------------------RTEYGLSLAQIRCLFQLRS-GDQTAGELAKSLGIRATSLTRMIERLETENWVKRQNDKHDRRRIVLTLTEEAEDMLSHLDFFLDSPAAMGIKRMTPQERVEFTQALQRFLQHV----- +>tr|H8L1H4|H8L1H4_FRAAD Homoprotocatechuate degradation operon regulator, HpaR OS=Frateuria aurantia (strain ATCC 33424 / DSM 6220 / NBRC 3245 / NCIMB +---------------------------------IVAEQGLTEQQWRIIRIMLDTGPIEPYQLVSLCSISSPSLTGILGRMEQQELVKRHKMGHDHRRRLIRLTDRGQALAETIVPRINEAYRQLESRLGEPLIASLVQTLEAVNARL----- +>tr|S3BF30|S3BF30_9BURK Uncharacterized protein OS=Sutterella wadsworthensis HGA0223 GN=HMPREF1476_01317 PE=4 SV=1 +-----------------AARMHEEGRRFLLTEMKKAGLDeLTTSCGDIFQVLFQ-qEGLSLTAVAQKIRRTKSTTCVMLDRLAKQGYVDRLPSESDGRASIIMLTEKGRALKPIMADISTRMNERILGSLTEDEADQLEVLLAKAVRTY----- +>tr|H1PPN2|H1PPN2_9FUSO Uncharacterized protein OS=Fusobacterium ulcerans 12-1B GN=HMPREF0402_00375 PE=4 SV=1 +-----------------LSRAHHRSRIFMDEELRKKGITdLGYSHIRIMIVLYV-fKTLSMKEITEKISKDKSTVTILVNKLEKKGYVRKRVCSKDRRVMHLELGERAEEVIGVIFDVSEIFHRKVEQILEKDEINTLKRIMSKLLEKW----- +>tr|U2Q7W0|U2Q7W0_9CLOT MarR family transcriptional regulator OS=Clostridium intestinale URNW GN=CINTURNW_0223 PE=4 SV=1 +-----------------FSKFLDKYNNSIEKKLKEENFIgLGASHFAILIGIiFSKeKRLCMKEIASFINKDKSTVTQLVNKLIRYDLIEKKYSESDKRMCYMMLSNKGRENEALFIKIYNESEA-ENNMITVEERQSIENIVKKLIISM----- +>tr|A0A1L8N243|A0A1L8N243_9SPIO Uncharacterized protein OS=Treponema sp. CETP13 GN=BKP49_04040 PE=4 SV=1 +-----------------ISRIDSLTSVYLKNKLEKQGISgIVSSHGFILHLLTLHKKLTMGEISKLINRDKSTTTALIKKLEQGGFLRKVTCKSDSRVRYIMLTPAGLKLTATTADISKELINTAYKNFSDSEKTELYTLLLKLEENF----- +>tr|A0A162BDH7|A0A162BDH7_9GAMM Uncharacterized protein OS=Marinomonas sp. TW1 GN=OA79_11925 PE=4 SV=1 +------------------------------HLAAEADILIPVTHIRAIKCITNIENCSARDIAKRLRLDKSQVARLVKDLLEQDYIEKDKHPTNNRCQVISLTAAGKGLQQKIAHVDNQARTQMCSGMTQQEIESFIQLTELMKSNLTQ--- +>tr|R6ELJ9|R6ELJ9_9FIRM Transcriptional regulator MarR family OS=Ruminococcus sp. CAG:563 GN=BN710_01010 PE=4 SV=1 +-----------------VHNELRSLSHLIYRFIENLpnkekIDSMTGTNACIIGYLTENADHDvfQKDIekAFGITR--STASKVINLMEQKGLVERHSVSCDARLKKIVMTDKSKAISHLMAEDMDLVESVLTDGFSSDEKEAMCDYIKRMKRNLKNY-- +>tr|R5HCW5|R5HCW5_9FIRM Transcriptional regulator MarR family OS=Firmicutes bacterium CAG:114 GN=BN469_00927 PE=4 SV=1 +-----------------QVTQLACIVNQLHRMAMRMppdvlPSGMTISQLSTIGFLYFSQQGDvyQKDIesFFKLRR--STVSSQLDTLEKKGLIQRVPVSHDARLKKLVLTEEGLRISGQVLLVLEQMNDFMIQGLSQEETVVLTNLLRKIEQNLSRI-- +>tr|A0A0T2YG83|A0A0T2YG83_9BURK Uncharacterized protein OS=Hydrogenophaga sp. Root209 GN=ASE11_14190 PE=4 SV=1 +--AKTEVLDHLHTLMHGLRR-------HLQEAARQDGDGLGPMEVRCLGYFLRHAGATQRDLVQHSGRDKAQIARIVKALHERGLLQSQPDPNDGRSQRVSVTPEGQALQRKMQLHRVRFEKSMTAGLSESERATLLALLGRLQENVGE--- +>tr|A0A1B9YJX9|A0A1B9YJX9_9BRAD Uncharacterized protein OS=Bradyrhizobium sp. LMTR 3 GN=LMTR3_09695 PE=4 SV=1 +--MDDELLDLFGAVANGLHA-------RLQGLTVLDELGLAPFQARTLSLIARYPGCSQQALSTSTGRDKAQVARAIKELETRGLITRQAHRRDWRAQSLSVTLEGKQASKLLLRHRAQAGADMLQDLNLKEREVLRCALSKMRARLGA--- +>tr|A0A1M7NRS2|A0A1M7NRS2_9BURK DNA-binding transcriptional regulator, MarR family OS=Duganella sacchari GN=SAMN05192549_104136 PE=4 SV=1 +--QSEQVFDAIHSIMHLYRA-------RQLRGLRDTPHEITHMEYKALGFFSRHPGATQGDLAAHSGRDKAQLARLLKGLRDKELLDAAADQADRRITRLTLSAQGQKIFNSLNQLGTQASSAAVDGMSAAQLTQLQALLQQIRDNLEA--- +>tr|A0A1L8MM34|A0A1L8MM34_9STRE MarR family transcriptional regulator OS=Streptococcus sp. NZ1587 GN=A9Q68_07370 PE=4 SV=1 +---------------------------------------------------------------------KSVASNLVKRMEKNGFIEVFPSQTDKRYKQVIMTQKGEDKLPLLQECRKDIENYFFKEITHEEFQVVRKVIDQLKQNMLD--- +>tr|A0A099CRU0|A0A099CRU0_9GAMM MarR family transcriptional regulator OS=Oleiagrimonas soli GN=LF63_0114275 PE=4 SV=1 +------------------------------AALQEEGVDLRFTQFLALKRLALDGPMCAGELARAVDHDAGAMTRVIDQLETKGYVRRQPHEQDRRSLRIAVTDAGMATWQHMAKAHERTLERAQQALSPAERVQLMDSLERVLAALR---- +>tr|F2IE50|F2IE50_FLUTR Regulatory protein MarR OS=Fluviicola taffensis (strain DSM 16823 / NCIMB 13979 / RW262) GN=Fluta_0360 PE=4 SV=1 +----------------------------------MEKTPVERYYFPLYL-IGKKNGiISQQELANQLLMDKVSLVRILDALESDGFIERKTNPNDRRQHLLNITSQAE----PWIGEIEKGiketNEYFFSLLDPSLHATFELILTELITKTQE--- +>tr|A0A143YYB4|A0A143YYB4_9LACT Helix turn helix multiple antibiotic resistance protein OS=Trichococcus sp. ES5 GN=TES5_1778 PE=4 SV=1 +-------------LLISLSKLSKVYRAEVKVE--MSASDFSPNELDLITFLSNNEMDTSKEIADFLGLSKSLIARSVDSLVAKGYLETNVDEGDRRYIHLVLTDRAKPIADRLRNIRKQFIASMTEGINQEQFTQFEATLEKMVANVERK-- +>tr|B9Y429|B9Y429_9FIRM Transcriptional regulator, MarR family OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_00560 PE=4 SV=1 +-------------MLKGYARLREAYSRFCAHS--AAGEAFSPNEMNVLIFLSNNPsINTAKELTVTLGVSKGLVCRSVDALVRRGYLTSEEDAKDHRILHLRLTQKAAPVIGQMRVSMDHFSQTVTRGISEEELAVYTRVQHQIYANIEAM-- +>tr|T0T767|T0T767_9DELT MarR family protein OS=Bacteriovorax sp. DB6_IX GN=M901_0279 PE=4 SV=1 +-------------IPLSMGLMKSYIRKVCE-------AEFSFSKFRIIALTQS--gKSTVSEIAEMMHISRPAVSKLVESLVTDKYLLRHTDEEDRRVIHLTATTKGKKKFQKVRHLASQMFIENLEGLNPLEIKELSQALSILENFVLQA-- +>tr|R5KH73|R5KH73_9CLOT Transcriptional regulator MarR family OS=Clostridium sp. CAG:264 GN=BN572_01559 PE=4 SV=1 +-------------IFDMTKSLMKLQEKYLESI--RIDYKLSRIEVIIITFLHNNPvHDTARDIVEFRMLQRGNVSTAIDSLADKGYLTRHPDTNDKRIIHLKLSDRSIPVVHAIEKKQDELISCIFEGFSDDEKKNFASYNKRLYDNVLSH-- +>tr|F4GH30|F4GH30_SPHCD Regulatory protein MarR OS=Sphaerochaeta coccoides (strain ATCC BAA-1237 / DSM 17374 / SPN1) GN=Spico_0275 PE=4 SV=1 +-------------FYLYAKLIKRMYESALTKA--AATIKLTLPEADVLCFLRENPeFDTARDVALYRDVSRPYVSKAVELLVNKGYLIVSGDKDDRRLQHLTITERGKPAAEVLHKAQYAFYDSVTAKLTQEETSMLLTLIGKCAETLNP--- +>tr|A0A127EFK8|A0A127EFK8_CLOPF MarR family transcriptional regulator OS=Clostridium perfringens GN=BXT94_03155 PE=4 SV=1 +-------------FLVSFTKAKKTYKKFISPT--LNDLGLTHNEFEILVFLQENLeYNTAKDIVEFSGLSKGLISRSIESLLKKEMLSIKKDDKDKRIFRLYISPSANETLNILNKVSNRFFKLLLEDLKDEELIFFDEVLNKMIKNLNNL-- +>tr|A0A1A0RKH0|A0A1A0RKH0_9MYCO MarR family transcriptional regulator OS=Mycobacterium sp. 852002-51961_SCH5331710 GN=A5752_20865 PE=4 SV=1 +----------------------------------LEPFGVEPRTYAVLKALSEADGQTQRQLSVQLNIHRNVMVTVIDKLENQGLVKRMPHPGDRRAFAVTLTGKARELLPKLDEQGRKQEAEITAPFTAAERKTVLRDLQRMSAA------ +>tr|C5T920|C5T920_ACIDE Transcriptional regulator, MarR family OS=Acidovorax delafieldii 2AN GN=AcdelDRAFT_3400 PE=4 SV=1 +-----------------------------------DAQGLTTQQWAVLGALSRpeaADGMSVGDLARYLMVSRQNLSGLISRMERDGHLGSAPDGRDRRSRRITMTDSGRGVWVNeAQPNIRRYYGQVLADFSVGDMAHTLHYLLKLLDNMQRL-- +>tr|R6M4Y3|R6M4Y3_9FIRM Uncharacterized protein OS=Megamonas funiformis CAG:377 GN=BN632_00317 PE=4 SV=1 +---------------------------------NLVSLGVTVQQALVIAYLDKSKDKkvTQRMIEIGLNNTNPTVTNIIKSMMSKNLIYKIQDKVDKRKYYLYLTPLGLSIASECAKRMEATDIAAYKNLTEEELKTLRVLLEKVEF------- +>tr|A0A1L8REI4|A0A1L8REI4_9ENTE Uncharacterized protein OS=Enterococcus canis GN=RU97_GL002259 PE=4 SV=1 +---------------------------------QLKSFDLTFSQFRILIYLHE-QLEptSMKAVEREFSLTQQTVAGLVKRLESKGFLYTKESPTDKRAKEIRLTEKGEASYQEAAGAYYQAQTSLTKGLSAAEEMELQRMLKILLNNMS---- +>tr|W6WZ06|W6WZ06_9BURK Transcriptional regulator, MarR family OS=Burkholderia sp. BT03 GN=PMI06_003285 PE=4 SV=1 +----------RGRTVPWMARTVHRLyDAQAQKILDRENL--PIAYWYYLRVLAARGEINQLELSKRVGIASTTAVPALDNLEKRGLVQRTRDPNDRRKYFVSLKDDGKRLVDEMMPELIDMISASLDGITQRDMRVFWKVMHQIENNLNQASQ +>tr|A0A1V4ENY1|A0A1V4ENY1_9ACTN Uncharacterized protein OS=Microbispora sp. GKU 823 GN=B1L11_00020 PE=4 SV=1 +----------LATSVCWLLGDAARElTQELERVLRKDDL--RWRDYGVLVVLEAAGPLSQQEIGRRLSVDRSTMVHVIDVLEERGLVARARDAADRRAYSIRLTDSGRALLVDVLhPATEAVQERVLGGLAAEDRMHLNRVLAQLAAGR----- +>tr|R7F1R0|R7F1R0_9BACI Uncharacterized protein OS=Bacillus sp. CAG:988 GN=BN822_01037 PE=4 SV=1 +--------------LYLTKRAHPFFESRMGAITNQIG--LTPQEGHILLFLAN---NPDCNHAcdavVYRGLSKSYVSKALTSLSKKGLIVFQEDTSDHRYQKIVFTETAQEKVKVLQEGQKALFKELIQGLSKEDLDVCKKVLNQIFQNFIKL-- +>tr|E2NU45|E2NU45_9FIRM Transcriptional regulator, MarR family OS=Catenibacterium mitsuokai DSM 15897 GN=CATMIT_02120 PE=4 SV=1 +--------------WDQHKTITLYYEMLTASTCDKYN--LKKMEYDILMFLYH---NPEYNTAadivRIRKSTKSHVSTALKVLEDRGYITKKTNENNKKRVELFLEDSANEIVKEGLNVQNQFAHDMLQGLTQDEIKVCKKVFEKICRNAEEC-- +>tr|R7HVX4|R7HVX4_9CLOT Transcriptional regulator MarR family OS=Clostridium sp. CAG:411 GN=BN648_01666 PE=4 SV=1 +--------------VQPSVLIKKLLEKKIAPIMKEYD--LRIVELDILFFLSK---DEHLDTAkeimQKKHLSKAHISKSIDNLKKRNLIRISEDAQDHRILHIALDESAYKVVDKVMKVYTECLQTIHKGITEEEWETVHRVLHKMLQNIEEA-- +>tr|A0A1C6E7S8|A0A1C6E7S8_9FIRM Transcriptional repressor MprA OS=uncultured Oscillibacter sp. GN=SAMEA3545356_00076 PE=4 SV=1 +--------------LRVIQQFRRYYDRHFSELLSRTG--LSMREIHVVLFLAN---HPAHDTArdvtELRGLAKSQVSAAVDLLAARELLRRQPDKADRRVIHLALTDAGAALAREGQKLQSTCLDALFAGLTQSEAERFQELLEKVLTSAEVR-- +>tr|A0A1C6GPP6|A0A1C6GPP6_9CLOT Transcriptional regulator SlyA OS=uncultured Butyricicoccus sp. GN=SAMEA3545389_02071 PE=4 SV=1 +--------------AADAFHAGQLYRSCFRELTESCG--FTPNEMFVLLFLYRN--APEQDTAtviaQAWNVSKPLVTRSVDGLQKRGLLYCVRDENDRRLVHLHLSDEGHAAAKTLHHRCETFALTLQQGISEQEMQTLCSVMQKMQRNLNDL-- +>tr|A0A1C5NVQ6|A0A1C5NVQ6_9FIRM Transcriptional regulator SlyA OS=uncultured Blautia sp. GN=SAMEA3545264_00164 PE=4 SV=1 +--------------LISGNAYKRVYEKRLEGLKSKYG--LKRIDLDILYFLCR---YRQRNTSkeitEQNQYTKGHVSQSIERLVKKGLVRTMPDEADRRCLRIIPEESAEAVYAKMHQVREQMFGDIFRGISQKDIGAFERVSQKVYENMHEE-- +>tr|A0A1C5UL37|A0A1C5UL37_9CLOT Transcriptional regulator SlyA OS=uncultured Clostridium sp. GN=SAMEA2393091_03095 PE=4 SV=1 +--------------LFMIHNSLELYENLCQPVCRECG--IAQTALDILMFLAN---NPEYYTArdicRVRGIKANLVSFHVEKLVQEGYLEREAIPGDRRQVRLLLTGKSQRVIEQGRSVQQRYREILVSNIAPSDFETFQRCMDTIRQNIERA-- +>tr|A0A1C5QG60|A0A1C5QG60_9CLOT Salmolysin OS=uncultured Clostridium sp. GN=slyA PE=4 SV=1 +--------------VFWNMHFKELFQLVYAQYGEIHH--LTETEIQILLFLRD---DSVYNTArdicKMRGIAKSNVSNGIRMLERKGYVSIRIDEENRKIHRLSLTEKSRPIAAELWQIYEDCQMRILDGITKEEVKAVYGFFEKCDVNVVKE-- +>tr|A0A1H6GBT6|A0A1H6GBT6_9GAMM Transcriptional regulator, MarR family (Fragment) OS=methanotrophic bacterial endosymbiont of Bathymodiolus sp. GN=METH_1349140 +--------------LKLIERISTLLRAEQRKKYSSLG--LQPVHVQTLDYLANC--NRFSDTPaavtDYLGLTKGTVSQTLQVLERKGYLEKIQDLVDKRIVHLKILPLGQQLLKSITPFD---------VFTKAEQAIANKQFDSISAALYEA-- +>tr|A0A1Q6LYV6|A0A1Q6LYV6_9CLOT Uncharacterized protein OS=Clostridium sp. 44_14 GN=BHW06_03790 PE=4 SV=1 +--------------LLSGQYFKKYQEAMYSEITEKFN--MTLMEVRVLLFFDN---HGSSNTAkdlvRIFHYTKSNVSKAIDSLLLRGYLKKQYDDQDRRYIHLTVQPEAADVLEMARQCQKDMFQSVFRGISEEELQIVQKVAQKIHQNISEA-- +>tr|A0A1M4SXU9|A0A1M4SXU9_9CLOT Winged helix DNA-binding domain-containing protein OS=Lactonifactor longoviformis DSM 17459 GN=SAMN02745158_00317 PE=4 SV=1 +--------------WLLIASLKKEYFNRKKTVISRFQ--ISSAELDILLFLAN---NKRFDTSadivRLRKMQKSHVSLAVKELTQKGYLTCEMNSFNHKKLHLKLTEASKEIVQAGQTMQREYLEFIFAGFSKEERLHVLEFCSKIETNLHGK-- +>tr|A0A1Y4SJZ3|A0A1Y4SJZ3_9FIRM MarR family transcriptional regulator OS=Massiliomicrobiota sp. An134 GN=B5E79_08030 PE=4 SV=1 +--------------LGMHPYIIKKYNSLFDELLKEYQ--MTQVEIDVLAFLAN---NPEYNHAqdivNVRGISKGHVSLAIEKLVKRGLVTRNPDPVNRRWNILCVEKKAGELVKKIQNIQHAFDEQAYQNISQEDIVKYHEILQQVYHNLGGG-- +>tr|A0A136MZQ4|A0A136MZQ4_9BACT MarR family transcriptional regulator OS=Bacteroidetes bacterium OLB9 GN=UZ09_BCD002000897 PE=4 SV=1 +---------------------AKLMKLIlSRNLLSSPEIDLTVDQWVIMHLIDEHKTLSQQQLGELALKDAPTITRMLDLMETRKLIVRAPDKSDKRKFQIRLTSIGKEKYLTATPIIHSFRSDAYKGLTREELMHLENM------------- +>tr|I2F5Z8|I2F5Z8_9BACT Transcriptional regulator OS=Mesotoga prima MesG1.Ag.4.2 GN=Theba_1691 PE=4 SV=1 +---------------------------------ALEPHGITYPQFGALLVLSSRGEMTQKQLSSHLETDTTNTMVICVGLEKKQLITREQSSEDKRANIVSITAKGREIFQKSMAVLRESYGPTANSISEKKRDTVNSVLDKLLESLN---- +>tr|A0A0V8T5K4|A0A0V8T5K4_PSESD Transcriptional regulator OS=Pseudomonas sp. (strain ADP) GN=AOX63_30100 PE=4 SV=1 +-PPQDHLFALTGSLQPARRAWQQAASLVLAES----GLSL-AVATPVLLVSRMGDGVLQNVLADCIGVHPAALVRTLDQAEAAGLLERRMVPGNRRLRAIHLQDAGRELAERLEKALNALRAEVLGSIPREDVETATRVLRLMEEKAR---- +>tr|A0A087NBJ0|A0A087NBJ0_9SPHN MarR-family transcriptional regulator OS=Sphingobium sp. ba1 GN=IL54_1910 PE=4 SV=1 +-ADAEQELALLHLLAPVARGWRQMGDAALAQF----GVSS-SAGWCLMHLDQLEEPPRQAELALLLDISPPSLVRTLDQLQIAGWIERIADPDDKRSNRLALTEAGKALAEKIAARLAEVREGLLGGLPDGAVEVGVELLGLLSLRMA---- +>tr|F0RPZ9|F0RPZ9_DEIPM Regulatory protein MarR OS=Deinococcus proteolyticus (strain ATCC 35074 / DSM 20540 / JCM 6276 / NBRC 101906 / NCIMB 13154 / VK +----TKYSEVSEEAVVSLMRTYAVVMADFDQFVRQFG--ITPAQYNILRILSGAEraGeqLGRNEIRRRLIDRvSPDVSRMLTRLEKAGLVSRDRrrrEGEDQRLVPVQITAQGLELLARVEGPLAERNMHSMAALTTAEQLQLIGLLERIRKGIRAL-- +>tr|I0II53|I0II53_PHYMF MarR family transcriptional regulator OS=Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01) GN=PSMK_27820 P +----GPFDFVQQELYLNLVRTASIAAEPVQRCLKAHG--LREPAFNVLRIVAGRGaeGLPSQAIGAHTVSRVPDITRLVDGLEKRGLVERRRCPHDRRVVHVVITAAGRRKAERASRDVDAVHRSQFPGLTEPRIARLIRLLERARERDAGE-- +>tr|A0A117UQN4|A0A117UQN4_9BACT Uncharacterized protein OS=Rhodothermaceae bacterium RA GN=AWN76_10440 PE=4 SV=1 +----SAIDQRELEAFTRALRR---IGVVFMRIAGQHS--TahetySKQELLALGVLRVSGpcR--MGEVAEHLGVGQSAVTPLVDRLEAQGLVRRRRSDEDRRVWLVALTEKGEAVVAEEDQVYQHVATEMLAPLSASERATLIALLERVGAAVPEG-- +>tr|A0A1H1M556|A0A1H1M556_9MICO DNA-binding transcriptional regulator, MarR family OS=Brevibacterium sandarakinum GN=SAMN04489751_0547 PE=4 SV=1 +----WNDSTDGMTTVISVMRVHQLFLAKVDAALKPFA--LTFSRYEVLTLLSFTKsgTLPMSKISARLQVHATSTTNSVDRLEKAGLVKRRSHPDDRRTTLVELTDTGRALSSRATAALNDEVFS-SPALAGADLGGLLPHLESLRSELEGR-- +>tr|A0A1Q3H413|A0A1Q3H413_9BACT MarR family transcriptional regulator OS=marine bacterium AO1-C GN=BKI52_04610 PE=4 SV=1 +----RTFPDSKHKLVVNLTHTSNWIKNRYTEFLKSYD--ISTQQMNILRISRAEGdWSPMNTVKELMIEKAPNATRIADKLVTKGLIERSRSQEDRRVVFIKITQKGLDLLKEFDIAHEKSLFRFTDNITDKEAELVSNILDRLRE------- +>tr|A0A1T5JZJ0|A0A1T5JZJ0_9CLOT MarR family transcriptional regulator, 2-MHQ and catechol-resistance regulon repressor OS=Maledivibacter halophilus GN=SAMN0219 +----NWIGEIANKTIIELQKTAGILEEIHNTFFNQFD--ISSTKFNLLVILYNSSqdGITLSEIGEEMLVTKANITGLVDRLEKQGYVSRKRHSQDRRKVIAAITKQGRKFTEKVIREYKIWSKDVMTILNDEEKKQLLNLFNKLQRGLVSK-- +>tr|A0A1V1U8S5|A0A1V1U8S5_9FIRM MarR family transcriptional regulator OS=Carboxydocella sp. ULO1 GN=ULO1_19990 PE=4 SV=1 +----EKRTVQAEEINLLLKSIIGHFRKFVSNHIKDLG--LTVPQLLLLRVLYQQPeqT--LSELCQQLGLAKSTVSDLVDRLEKQELVVKRRGEQDRRTVRISLAEKTMALGETIQAIKTDYWSALLSQLTPAEVEEILRALRKLQGLISAS-- +>tr|D4H6T8|D4H6T8_DENA2 Transcriptional regulator, MarR family OS=Denitrovibrio acetiphilus (strain DSM 12809 / N2460) GN=Dacet_1028 PE=4 SV=1 +-----------------------------------NEAGVTFSQFEVLVVVYHFAPMTVNSIIENTLSTIGNISLVVTNLIKDGFLKSEVHESDKRSKLITLTQKGEEFMDDFFPTHLRNIENIFSVYTQEEKELLLSLMRKLYRD------ +>tr|U3VDL9|U3VDL9_CLODI Transcriptional regulator, MarR family OS=Peptoclostridium difficile E10 GN=BN166_2230027 PE=4 SV=1 +------------ELLKWVSI----INRYNTNYIdrKLADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGVKDKRTWHLYPTEKSLECYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLA----- +>tr|A0A0R1GWB3|A0A0R1GWB3_9LACO Transcriptional regulator OS=Lactobacillus parabrevis ATCC 53295 GN=FD07_GL002101 PE=4 SV=1 +------------DIVKWLSI----ANRYTRIALdrRLQPYRLNASMYYYILRLHEQPRLTQDKLISLTYLNPSNVTRAVNQLVNLGYVRKRQSKLDRRVYELSLTKRGERLYPEIVKIRQEVANSLLTEIPAADHDALVDQIRQLALTA----- +>tr|F8HY14|F8HY14_WEIKK Transcriptional regulator OS=Weissella koreensis (strain KACC 15510) GN=WKK_00570 PE=4 SV=1 +------------DQLQSFGI----VSRVIRTELnrVLKPYGLNDSNYFFISYIADHPESSQGDLTRTMFLDHSTITRSVAKLVELGYLEKHLDEKDHRTTRLFLTNKGAEIRYEIHELTTTIFDNTFSEISSEESETIKSILLKTANHL----- +>tr|A0A0R2EZ79|A0A0R2EZ79_9LACO Uncharacterized protein OS=Lactobacillus camelliae DSM 22697 = JCM 13995 GN=FC75_GL002344 PE=4 SV=1 +------------TIMKQLHV----ASNIALRVLerRLKPLGVNSSQYFFVLKLHDDPGVTQDQLVREDSRHQSNVNREISRLVDLGFVDKRQSTTDGRRYQLWLTEAGEDLYPKVKAALDAQEKVLSECLTAadgrVTQADFLAVLHRITQLD----- +>tr|A0A1Z5J505|A0A1Z5J505_9LACO MarR family transcriptional regulator OS=Lactobacillus silagincola GN=marR_20 PE=4 SV=1 +------------DFVQQVAV----LNLVITNHIteMLAPYEVNASNYFYVMKISENPGITRSDFNQLVHLNHSSITRAVNHLIEKGLIKQSINPRDKRGTQLFLTDKGIQLNREITQKISELNANLMAKLEPQQQTIFSNIVK-LRQSI----- +>tr|A0A1K1PR94|A0A1K1PR94_9FLAO DNA-binding transcriptional regulator, MarR family OS=Sinomicrobium oceani GN=SAMN02927921_01955 PE=4 SV=1 +--------------------------------------------SQVIFLVKEQGKTTATAINKVLQLDEGYLSRIIKKLISDSLLIKEQSQTDKRCFEIMLSPKGIEEQRKMDKLSSESVRAIISHLSETEQQELAGSFQRIMALL----- +>tr|A0A1H6BYL1|A0A1H6BYL1_9GAMM DNA-binding transcriptional regulator, MarR family OS=Marinobacterium lutimaris GN=SAMN05444390_10315 PE=4 SV=1 +----------------------------IAAFKSFEGVTtgygsIPRYY-GLLELLSNNPGVTHNRLAEAVYLDKSSLVSILDMLQKEGVIKREPSDTDRRVKNLFITPKGAELLNDLNRHVTEHESMLMAGFSDEERSTLVNMLDKIDNNIR---- +>tr|A0A1C6IT89|A0A1C6IT89_9CLOT MarR family OS=uncultured Butyricicoccus sp. GN=SAMEA3545389_02699 PE=4 SV=1 +---------------------------------DLKSMGLAAEQADTLLFFHAHSGSSASDLRCSLGVTHQAARALVQRMADKGLLCVTPSPRDARYKLIALTAEGEELYETMQRNCTNFGDRLLEHIPADDREKLLAMISQALDNMEK--- +>tr|A0A1Z5IXQ4|A0A1Z5IXQ4_9LACO MarR family transcriptional regulator OS=Lactobacillus pentosiphilus GN=marR_13 PE=4 SV=1 +---------------------------------HIRDLHITTDQADALIYYHDFPDQTISDLKNFQHIRHQSAQVITQKLVDKGLVTLIKNPNDRRAKLVVLTDAGNMMRLHLKNNGSRTGEQLLNGFSDNEKQQFLTLLEKSISNLNR--- +>tr|M9R961|M9R961_9RHOB Transcriptional regulator OS=Octadecabacter antarcticus 307 GN=OAN307_c37350 PE=4 SV=1 +--------------PVSIGRQLNITASVGNAVCNqlLEPHDLTLAQWAVLSSLWQNGDMSLKDLAKLTGNAPPATSRIVERMVMGGLLLRTQNNKDRRAVSVSLSPKAEG-FRYLHTIYEDVNAVLLADLTASEQAQLFKLLRKVEENARNWV- +>tr|A0A1F4EIZ7|A0A1F4EIZ7_9BURK Uncharacterized protein OS=Burkholderiales bacterium RIFCSPHIGHO2_01_FULL_64_960 GN=A2710_07150 PE=4 SV=1 +-------------------------------------FGMGVNEWRVLSYVELFPWSTGTQMCDLMGVDKSAVSRGCAVLMEHGLIVSRPRGLRKIEY--GITPKGKVAFQQFLRVSVARQEALLTGFSNTERKLLISFMHRLLDNLPLA-- +>tr|A0A1T5GWH0|A0A1T5GWH0_9SPHN DNA-binding transcriptional regulator, MarR family OS=Sphingomonas histidinilytica GN=SAMN06295920_12226 PE=4 SV=1 +-------------------------------------FGLGILEFRLLVMLAAEPDIPPSRICEVMGLDGGAVSRALRGMEARGLVVSRPDRRNPAYKLWSLTAEGARLQDEAVLVSMERDAILLADFTDAERSELIAMLRRMLARVDRL-- +>tr|A0A1R1FU34|A0A1R1FU34_9BACL MarR family transcriptional regulator OS=Paenibacillus sp. FSL R7-0337 GN=BK147_33320 PE=4 SV=1 +----HSIKTIELEMAVLFRRLTSItTFK--------KIGNLDRAAYLLLHHIeSREGTAGIKAISDEFQLDISTVSRQAASLESKGHITRVPDPVDGRAYSLQITETGKASLEENRRVRQEMIEQLLKGWSEEEGHLFGELLQKFNAAF----- +>tr|A0A1M4X0I0|A0A1M4X0I0_9BACL DNA-binding transcriptional regulator, MarR family OS=Seinonella peptonophila GN=SAMN05444392_10463 PE=4 SV=1 +---SENLNQIDHEIVMLMLRADFKkaLDR--------NKESLERSSYLILKELMESRVRGLSELAEHFQLDLSTISRQIRILEKNNYIRRFVHPQDARIKLIEITKNGIEVLQKTQKKRLKAYHELTHDWTSEEVTMFAQLLTRLNRAM----- +>tr|A0A1V4Q446|A0A1V4Q446_9ACTN Transcriptional regulator OS=Gordonia sp. i37 GN=B1964_18935 PE=4 SV=1 +---DRDIDQLFDTLARYVRIRDRAvhTtfRT--------PDGEFETAAFKGLFHL-AKRPMRSRELAAELGADPSTVSRHVSQLVDLGLIRREADPHDGRATLLVVTDAGRDRVESMRAGRRSAVNSAMSEWSADEMATLVTLLTRFVDAA----- +>tr|A0A1M6F776|A0A1M6F776_9DELT Transcriptional regulator, MarR family OS=Desulfatibacillum alkenivorans DSM 16219 GN=SAMN02745216_00740 PE=4 SV=1 +----------------------------LQNAFAENEIAVSPMQARILFALKGRSPRTMTQLSKALSTDNAAITRLVEKLVKMGVVERKNSPHDRRAYLIEITPRGNEEIAKAEAVMHLVNEEFSALFTPDQKAVLQGFLSEIE-------- +>tr|A0A150YC03|A0A150YC03_9FIRM Uncharacterized protein OS=Ruminococcus sp. DSM 100440 GN=AXF09_02615 PE=4 SV=1 +-----------------------------RPYFQEIGLTVGQGQPRILNSLRKYGTMTQRELADCCFVDVTTISRTVDRLVAAGLLSKQIDPECRRSCLISLTEEGRKKAVQVQHIFEKGDEIWWKSFDEEELERLYQYLLKMEQSLKGD-- +>tr|A0A1Q3YNA1|A0A1Q3YNA1_9BURK Uncharacterized protein OS=Burkholderiales bacterium 70-64 GN=BGO72_20985 PE=4 SV=1 +----------------------------------LTRSGVTIAQWRVYMCLLTHGPSHLNGIVAFTHLPQSSLSRSIAAMHDRGLVRNARNATDRRIARIEITPKGRRHLAALTEKIDAACADAF-RLSPAEEVRLIRRLDVLIARLSD--- +>tr|A0A0C2DJH5|A0A0C2DJH5_9STAP MarR family transcriptional regulator OS=Salinicoccus roseus GN=SN16_11660 PE=4 SV=1 +----------------------------------LKKYELSPLQFVALQWVDDKEGITIGELSNRLDLAHSTTTDIVDKLENGAFVKRQKYEKDKRIVLVLMQDKGHQIIKEVIAKRISYISEITSHLSADEKEMLPVILESILQESE---- +>tr|M1ZGD3|M1ZGD3_9FIRM Putative Uncharacterized HTH-type transcriptional regulator YsmB OS=[Clostridium] ultunense Esp GN=CULT_710039 PE=4 SV=1 +----------------------------------AQEYGLTYDQYHLLIYLsFSEk-PPTINEISKKFNRAQNTISEKISRLEEKELVSRVDDPKDRRVTRVIITERGLDLIHTIRQERSNRVTYIALeKMEKDEIENLLTNLSILYNNLK---- +>tr|A0A1F7RCL7|A0A1F7RCL7_9BACT Uncharacterized protein OS=Candidatus Schekmanbacteria bacterium GWA2_38_11 GN=A2042_01375 PE=4 SV=1 +----------------------------------FSNVHITGPQFATLVYLSRDn-NCTMGRLKENLDLSLSTLTGIVDRMIKAGYVERQRDGNDRRVVRVRMTKKGEEVSKELNKKRHEKIITILQLLKRedqeLLIGTFERLTSHLVQNSK---- +>tr|A0A223HV62|A0A223HV62_THETR MarR family transcriptional regulator OS=Thermoanaerobacterium thermosaccharolyticum GN=Thert_00083 PE=4 SV=1 +----------------------------------LNSKNITMSRFWVLNKLHSDe-AITMKQLQSQLLLSPSTLTGLIDNLVADDLVSRWRDTKDRRLVFLKLTVKGSNLLNEILEYRTLVLKKIVSKCTKdIDLNMLNKNLETLLKMSN---- +>tr|A0A0V8GCA6|A0A0V8GCA6_9BACL Uncharacterized protein OS=Exiguobacterium enclense GN=AS033_14280 PE=4 SV=1 +----------------------------VNAF--LKQWDLSHTNLEVLRCLQTTSCTSQKEIAERIQVTDGTISHGIKRLFDRQLITRKR---KWKTNYLLLTEKGTAILQEVLPAYERFQQEQFAALTARQQEELIRFFDKLNPA------ +>tr|A0A0R2AWG0|A0A0R2AWG0_9LACO MarR family transcriptional regulator OS=Lactobacillus murinus DSM 20452 = NBRC 14221 GN=FC48_GL001553 PE=4 SV=1 +----------------------------SATV--LQQVGITNAQYDILNYVYNHTGRTQKELATTLVVTKGNITQIITKMERLDLIKRKQ---VGKAKQLFVTENGRQIYEQITPKLEKAHADALAKLDLTEQKQLLRLLKLALRG------ +>tr|C5USK5|C5USK5_CLOBO Transcriptional regulator, MarR family OS=Clostridium botulinum E1 str. 'BoNT E Beluga' GN=CLO_1452 PE=4 SV=1 +----------------KMTTVSELANRINDEFYK--QFKLTRIQFRTLYFlhVFMKEGCSLSELSKKLHISKPSSSNLIDRMVSSGLVTRISNSEDRRSIKILITSKGIKIIEQAINRDKDFRLQILNFLSNEERQTLYKILVKMEKNMT---- +>tr|J2VFA9|J2VFA9_9RHIZ Transcriptional regulator OS=Phyllobacterium sp. YR531 GN=PMI41_02302 PE=4 SV=1 +----------------------------------LLGHGFYAGQDAVMLQLAHEDGLSPSVLAKRLGVRPPTITKTISRLQTQGFVKKEGSSTDQRQAHIFLTDTGNEAIKSIEKSIRKTEKDAMKGFDKKERKAFVKMLTRLEMNLSAA-- +>tr|A0A1N6LIT5|A0A1N6LIT5_9BURK Transcriptional regulator, MarR family OS=Burkholderia sp. GAS332 GN=SAMN05444172_5026 PE=4 SV=1 +-----------------------------------AALDMTPSQYGVLYILFHSGPLEQIGIARLIGLDRSTTALVVKILSERGLLEKAKSETDQRKVEISLTEAGQQCFRQCERYAQKSVEALLAPFDPAERTQFLALLDKFVSHFND--- +>tr|A0A143Y6M7|A0A143Y6M7_9LACT Transcriptional regulator marr-type conserved site OS=Trichococcus palustris GN=Tpal_399 PE=4 SV=1 +-------RALDQQLCFEVYRASNGFSKMYGRA--LKPFQLTFPQYLVLLALWDADGVLIKNIGERLGMGIGTLNPIMTRLEKQDWIKKTPSLGDKRSVIVSLTEKGKRS---KRDIALSILKEISIcNFTGIEGETLMKQLKILNRAFAAM-- +>tr|A0A0R2L779|A0A0R2L779_9LACO MarR family transcriptional regulator OS=Lactobacillus siliginis GN=IV55_GL000192 PE=4 SV=1 +-------RLLDDQLCVAVYNANKRFNRFYMET--LKPYNLTFPQYIALCALWENDKQTVNEIGEKLSLDSGTLTPLLRRLEQNGWVKRTRSKSDERQVIVRLSTKAKEQ---RDEIYQHVTDCQDLlAYDDVTYADSRSAVKDLSNRLASV-- +>tr|C6XKS5|C6XKS5_HIRBI Transcriptional regulator, MarR family OS=Hirschia baltica (strain ATCC 49814 / DSM 5838 / IFAM 1418) GN=Hbal_1958 PE=4 SV=1 +-------AKFDQNVLPWIGRIERQFSILMKEA--LAPLDLTYPEFRLVGVLWGEEEgHPQKYLAARLGLDASAVSVTLKSLEKNKIVERVRDQNDARIVRVKCAPKAYEM---TQVLSAHSEQEmSATsGFSDTEKQQLLQLLTRVSQNLSQK-- +>tr|A0A088T4A1|A0A088T4A1_9BACT MarR family protein OS=Candidatus Izimaplasma sp. HR1 GN=KQ51_01063 PE=4 SV=1 +--------------------------------------QIKGIRFKYLKEIHKRKEVTLTELADHFSISKPTVNEVINHFKANGIIEKRKSEKDKRINYISLTDIGVVLATTNTLESRRAVDRMFDKLPKKDIKTLVKIFSKL--------- +>tr|A0A0J1HCY3|A0A0J1HCY3_9GAMM Uncharacterized protein OS=Photobacterium aquae GN=ABT56_00215 PE=4 SV=1 +-----------------------------------------IEQLLMLMELNYEDGLRPSVLAERMMRSKGTISSLIKHAQRNEFIASSSDPNHKNAKRLYLTVYGKKVHDELTPIIDEELEAAMDGVPAELREEIVKVMFNVIRRNH---- +>tr|J2LHX6|J2LHX6_9BURK Transcriptional regulator OS=Herbaspirillum sp. CF444 GN=PMI16_03738 PE=4 SV=1 +--------------------------HLLQDAL--RPLEILPTEYRTLSAILRKGPLTMQELAQWTAYERTRVTRILHAMEARGWIARSASEHDKRSVVVQITDRGREMFWQAKVIVDQVTDQAMSDNSEEEIAQLRHGLTVLRKKL----- +>tr|B1YJZ3|B1YJZ3_EXIS2 Transcriptional regulator, MarR family OS=Exiguobacterium sibiricum (strain DSM 17290 / JCM 13490 / 255-15) GN=Exig_2179 PE=4 S +----------------------------------LLPFSLHTGQWGLIKAVAILEPVSQVALSKYLVIEKPAVTKTVARLEELGYITRTG---SGRKRLITLTPSARHAYREIDQAVQSAHHAFLQSVSFDDQSIIAAVMtqllATHRPDEQE--- +>tr|A0A0J6WYW2|A0A0J6WYW2_9FIRM Uncharacterized protein OS=Megasphaera cerevisiae DSM 20462 GN=AB840_02550 PE=4 SV=1 +----------------------------------LRPYGITYSQWVFIVYLSHHRQTSLAPIASYYQIERPAVTAIKNMFLQRRWIQEKTGQ-DRRERIISLTKQGTDTFAEINVKIRAMEHQFLASLTTKEQTDLQKLLYTLNQKEIL--- +>tr|A0A1W2EDZ0|A0A1W2EDZ0_9FIRM DNA-binding transcriptional regulator, MarR family OS=Sporomusa malonica GN=SAMN04488500_12330 PE=4 SV=1 +----------------------------------FSPYDLHFSEWGIIITLMEREPMTQRGLAAYLNVEPAAISKSLTRMERKGLIMREVGS-DRREKRVFLTEEAKKNYQVWNNIAGEHRKAVLADLDWGKKNEIYQLLKGICQATQQ--- +>tr|A0A166BRG5|A0A166BRG5_9EURY Transcriptional regulator SlyA OS=Methanobrevibacter oralis GN=slyA_1 PE=4 SV=1 +---------------------------------KAREFSIDVIDYYIILeiIHHNNNEFIQKDFAQLFDKNESSITRALNHLEKSGYIERILceDNK---SKLVKLSPTGRNIVLEVEKEVSKFDEYIFSDFSPENVKVGIKNLIDIANNS----- +>tr|A0A1B9TYR1|A0A1B9TYR1_9RHIZ Uncharacterized protein OS=Agrobacterium rubi GN=A6U92_22375 PE=4 SV=1 +----------------------------RQRISAhLADSQLTFIDFIVLSAIAEAANIPLGVIADSLDIGPSNFSNMVSLLERRKLVKRKPNGPDKRHRAILVTKRGKAVLQRASSVWIDSEEELTKQLGDTNRRIFVlQALRDLGK------- +>tr|A0A1W9IHX8|A0A1W9IHX8_9PROT Uncharacterized protein OS=Proteobacteria bacterium SG_bin9 GN=A4S14_04690 PE=4 SV=1 +----------------------------ISELNGiLSEFDLRIMDFAVLSIVETNPGIFQNEITHIVGAEPPALVLSLDRLEKANYLFRQFSPTDRRLRTLHLTTDGRKLIKKVTAKVERQERGITNAVR-GDLAQFVAGLDDLML------- +>tr|A0A177MQF3|A0A177MQF3_METMH MarR family transcriptional regulator OS=Methylomonas methanica GN=A1342_09985 PE=4 SV=1 +------------------LRTHQAFLSYAAR--HVHRLELTLPQYDVIITLGKTAGMQPKKLGEETLITKGTLTGVVSRLEDKGLVERSASKKDGRSQIIRLTEAGRAVYEQTFPEHLAHIGRLFDDYAPEEISKLEADLQRLHQAVITA-- +>tr|Q5LVU0|Q5LVU0_RUEPO Transcriptional regulator, MarR family OS=Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) GN=SPO0605 PE=4 SV=1 +------------------LRSQQLFMRAMGP--VFRAHGLTAPQWDALETLANKGPVSMNDLMRFTLSTSGNLDVVIKNLIQAGLIEKSVDPEDKRGRILQLSPEGRRKVDDFIPIHNQALDQLFSGLGTAGKRQTITALNQLRKTLTQA-- +>tr|E6W6Y0|E6W6Y0_DESIS Regulatory protein MarR OS=Desulfurispirillum indicum (strain ATCC BAA-1389 / S5) GN=Selin_1490 PE=4 SV=1 +------------------TEFEKSYKRAVDR--NIKKLGVSPSQFKVLKTLGERGSLKFKDVCDATLITKGTMTGVVNRLIKAGLVEKEQDVKDTRAWILSLTPKGKVDYVSLNKNYSQLVSSIFKGETEERLKQYITQLNSLQAIINQS-- +>tr|D6U5I9|D6U5I9_9CHLR Transcriptional regulator, MarR family OS=Ktedonobacter racemifer DSM 44963 GN=Krac_0830 PE=4 SV=1 +-----------------------------------VGMSQL--RRQLLTLLSEIGELSHAALQQQLAVDGATITRLVKQFESEGVLSRRLDPQDNRYTLVSLTVSGQQIVAGLRAAHRLFQTQLLNGIPREEQEMVLHVLERLHANIRA--- +>tr|A0A1V1IAA2|A0A1V1IAA2_CARML MarR family protein (Modular protein) OS=Carnobacterium maltaromaticum GN=BN1423_2290010 PE=4 SV=1 +-----------------------------------TECSLT--RYEIMHILAKKERVLQGDLQRAIKIDPAAVTRHLKKLEEEKCIVRERNSQNNREVYVQITPIGLTRMQACQSKTVDTLEQVYQGITNEQRKELTGIVEKISQNIST--- +>tr|A0A1E5BYN9|A0A1E5BYN9_9GAMM Transcriptional regulator OS=Enterovibrio norvegicus FF-454 GN=A1OK_15490 PE=4 SV=1 +----------------------------------LEPFKLTYPQFVVMMSLWQEQNVSVTELAQSVGLSKATVTPIIKRLQSVGYVTKTLVEGNERQKSVALTDEGKKLARAGKKVAK-QALC-ATGLTESEADTMISLSQKIRQNL----- +>tr|A0A0S9EYH1|A0A0S9EYH1_9BURK MarR family transcriptional regulator OS=Acidovorax sp. Leaf76 GN=ASF11_23965 PE=4 SV=1 +--------EPEESVGYLMRKVMSSIRTQ-ADA-QLSTHDLTYAQWLPLFKISRCDQTTVASLARDLETDPASMTRAMDRLEAKGLVVRERSTTDRRVVRLTLTPDGDQVASRVPAVLADVLNVHLSDFSHAEWQLLLSLLRRMLVN------ +>tr|A0A0F7JK93|A0A0F7JK93_9DEIO Uncharacterized protein OS='Deinococcus soli' Cha et al. 2014 GN=SY84_05420 PE=4 SV=1 +--------------------------------ATASGADLTPTTRDllftLHRSAPPEGLTPGE-LAALLAVSPASVTGSLDRLETRGLLRRAPDPQDRRAQRIHLTDTGRDLVRMHLPVH---LRREEDLLSPLSASERQQLEQ----------- +>tr|A0A136L801|A0A136L801_9CHLR MarR family transcriptional regulator OS=Chloroflexi bacterium OLB15 GN=UZ15_CFX003002399 PE=4 SV=1 +--------------------------------RETGNEEATMRQISVLMQLRKHPVTASE-LAKRNKVSLQASSVLVQGLVERGWLTRVRDPKDRRQWLLEVTPEGIASAEAAKKQLTGIIAEILSDLPSEALKSASVFLP----------- +>tr|T0QZ00|T0QZ00_9PROT MarR family protein OS=Bacteriovorax sp. Seq25_V GN=M900_0232 PE=4 SV=1 +-------------ILAANIRTTKLFDDLITKGIAQ--YGISKPQFDImvFIYFGEEKKTTVTEIAINNSVSKANVTGIMNRMITQGLIQSVVDQKDARVKNVTLTEKGEELMKTTVPVYQDLIRKTLSPFSHAEKELLLKQLKHIEGCIR---- +>tr|F2J6N6|F2J6N6_POLGS MarR family transcription regulator protein OS=Polymorphum gilvum (strain LMG 25793 / CGMCC 1.9160 / SL003B-26A1) GN=SL003B_410 +----------------LIRRIYQIFLYCFDEA--MAGLHLTPVTWILIATARNFPGLSVTELARRAAVDKASCGRTATMLEKRGLLLIRKSEADGRQKLLELTAAGMALAIAGEGRIELLRSLLLDQLDPDEGAQFVAQL------------ +>tr|A0A0B5DXQ0|A0A0B5DXQ0_9RHOB MarR family transcriptional regulator OS=Celeribacter indicus GN=P73_0307 PE=4 SV=1 +----------------LLRRAYQVFLFFFDDT--MKGLNMTPLLWILLTVTYCYPRRSVTDIAELSRIDKASCGRAATLLEKRGLMRIGTGEKDRRQRVLELTPHGHEVVLDGMSRTLEMQKKLLQCFDQEEARQFSHTQ------------ +>tr|R6MF15|R6MF15_9FIRM Uncharacterized protein OS=Acidaminococcus intestini CAG:325 GN=BN610_01556 PE=4 SV=1 +--------------------------------------------NRILFELYENERLSAKYLCNLLLLDKGYISRVISGFEKKNMITRKASSTDGRSQDISLTEYGIDEAKRVIEITYNKIFEMIENLNKEDCDAVCNAMICIEEKL----- +>tr|A0A1F8VGG2|A0A1F8VGG2_9BURK Uncharacterized protein OS=Curvibacter sp. GWA2_63_95 GN=A2037_00435 PE=4 SV=1 +--------NPEEDAIQAMLRMFEALKGQMTQSLAQTGIALSPLHLHILSHCKAHPGGNQQALVQASTRDKGQIARITKELEAQALLRRSPDPQDGRSQILEVTPVGLEACAVFEAQHTALVQRMFASVAPEQLAVFTAVARRATAQ------ +>tr|W7AR71|W7AR71_9LIST Putative MarR family transcriptional regulator OS=Listeria aquatica FSL S10-1188 GN=MAQA_11836 PE=4 SV=1 +---------------------------------ESDKKEITTAQLIALSTLKREPHLTLGELAERMKVSKSTASGIVDRLVRAGFLMRNRVEDNRRTLNLELTKLGEQKTAETYALFFDRLEPL-LDVGEESLLSMLETHKRIIEILER--- +>tr|A0A1F2Y5M5|A0A1F2Y5M5_9BACL Uncharacterized protein OS=Alicyclobacillus sp. RIFOXYA1_FULL_53_8 GN=A2201_08225 PE=4 SV=1 +---------------------------------VVQRFHMTASQLFILRYVDKHGPTKASDIAKSAGLSPGAVTQVCDELVRIQCIDRTRSDDDRRVVYIEVTDVGRDRLNEIRQTQFAGTEHILAQLGPEDAENFVRIVGRVVEIAEK--- +>tr|C7HW92|C7HW92_9FIRM Transcriptional regulator, MarR family OS=Anaerococcus vaginalis ATCC 51170 GN=HMPREF0078_1543 PE=4 SV=1 +--------------------------------------GVTTLQLKMIMTLSASdESVSIGNLGKSIGVNGGNISNICKKLEKQGFVDRNRSDEDERVVNVKLTQKGFDAAEKVSKYFDKIRPKEDEKRINSNLKTIINELDSLDNLLDD--- +>tr|V7I6P1|V7I6P1_9CLOT Uncharacterized protein OS=Youngiibacter fragilis 232.1 GN=T472_0203925 PE=4 SV=1 +--------------------------------------GLTPNQARIILIMSLEGSATMGRISDSASIAGGNLTNLCKVLENRGLVERGRDPDDDRKVLMRLTQSGSETAQRLDRWLTTRLEDRLPEY-RGELTEIAEALEKLSEMIIE--- +>tr|R6C7Y1|R6C7Y1_9FIRM Transcriptional regulator OS=Ruminococcus sp. CAG:579 GN=BN718_01347 PE=4 SV=1 +--------------------------------------GITNMQAMMLFMIKSEKAISVGALSSIFNMTHSNASALCKKLERDGLVCRTRSKTDERTVLITLGERGEEVLSRMLK-NGAGISDSLGEIPQDRLDTIIETMNEATHMLSQ--- +>tr|A0A1C5WFE2|A0A1C5WFE2_9CLOT Staphylococcal accessory regulator Z OS=uncultured Clostridium sp. GN=sarZ_1 PE=4 SV=1 +--------------------------------------GMTGIQGLVLMEVANDEECKLGALAQRLLMTNSNLSAIIKRMEEHGWIRRCRSPQDERIVYVRLSNEGAAILADIKKRMDAKL-DFLKQEDEESIKQMIQSLKRLDDLLQE--- +>tr|A0A1C0BSE9|A0A1C0BSE9_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium MTC7 GN=A4S06_05665 PE=4 SV=1 +--------------------------------------GLSKTHTLVLREVRTCEPITLNELSSNLSKVPANMSITVSELEDQGYLERERFVDDRRVTKIRLTEKGAEAVNLFDTYMEKNLHEMIED--EKTLKDILEKLESVYEKVKK--- +>tr|A0A1B7LZU2|A0A1B7LZU2_9MICC Uncharacterized protein OS=Enteractinococcus helveticum GN=A6F49_09385 PE=4 SV=1 +--------------------------------------KLSFFEYQVLEHLSSIEG-AmsMTQLATRCNSSLSRLSHVARKLEGRQLLTRRLSEEDKRVTVAELTEEGRYLVDGIREIyRQSVETRVLQSLSPEELRQVTGLLDSMLRKNE---- +>tr|R5CF02|R5CF02_9FIRM Transcriptional regulator MarR family OS=Firmicutes bacterium CAG:791 GN=BN785_01711 PE=4 SV=1 +---------------------------------DMNESDLTFSQMEILFYLEKHADHaiNQQELCDAVQVSHPTMIGLINRMEEKDLVVRRTDPLNRRSRYIEMTQKSQEILRQTRERRHRNDRMLVKGFTDEETKELNRLLGMVYRNMQ---- +>tr|A0A0R1JZC3|A0A0R1JZC3_9LACO Uncharacterized protein OS=Lactobacillus namurensis DSM 19117 GN=FD30_GL001368 PE=4 SV=1 +----------------NIGRNLKTLNNLVEKKLNNdlrsLGVSLTGTQMSVMMWLHNNQGVPltQKQIETELKLSHPTTRGINKRLVEAGLIETQVVAEDKRQIQLQLTPKGRDLLDSYSHQLKMKVDAveakMLTGIDANTQTILLSSIRTMIRNM----- +>tr|A0A0F4KP22|A0A0F4KP22_9LACO Uncharacterized protein OS=Lactobacillus mellis GN=JG29_08470 PE=4 SV=1 +----------------SLGPLIKVANNLIEKELNNnmrqLFteFNLTGPQVALLTYLYEAQSRTvsQKELETVFVISHPTIRSIVKRLEQRQLINISTLKSDRRQTILSLSASGSTLIKNNISKIYQVMNHinqkITQDITPNEQQQLIILVQKIVHNF----- +>tr|A0A0R2A5N1|A0A0R2A5N1_9LACO MarR family transcriptional regulator OS=Lactobacillus malefermentans DSM 5705 = KCTC 3548 GN=FD44_GL000434 PE=4 SV=1 +----------------LIGPKLKAVNTLFEKALSKridkTNspKRLTGGQMSVIAYLYDNPDDViyQRDLEKIFNLSRPTINGIIKRLSENGSIEIVPDEKDKRYKRIMLSKEALDAMIKYRPAFEQEVKQveneMTQGLDEKQVQDLKHLLDVCRDNL----- +>tr|W7SRH2|W7SRH2_9PSEU MarR-family transcriptional regulator OS=Kutzneria sp. 744 GN=KUTG_00610 PE=4 SV=1 +-------------------------------------AGISHSHFKVLALLAGAPDHTmgLTKLSQALRFHKSRLSHALAKLEAGGLLRREDTPEKGRAYQAVLTRAGLRLVNRALPLqDAFARDTVLAGLSREQIKQLRAIAEIISGNLEH--- +>tr|A0A0Q7RR45|A0A0Q7RR45_9RHIZ Uncharacterized protein OS=Ensifer sp. Root142 GN=ASD52_25720 PE=4 SV=1 +--------------------------FDLNGAVEaLAQVDARPISLSVLLCMVEKPGLTSAEICRILGMQRANIVQFLTDLEAKGLFTREAEASDQRVQRLFPTQAGREAAADWLHRLNEHEDRMLERLDAQERAELRRLLSKVW-------- +>tr|A0A1E4MDZ0|A0A1E4MDZ0_9SPHN MarR family transcriptional regulator OS=Novosphingobium sp. SCN 66-18 GN=ABT11_12380 PE=4 SV=1 +--------------------------VADALFSEtFGEMEITAAQYAILMVVRHNPGCRTSTAGSLLGITPNNLVPLLDSLTARGYIRRTLSTTDRRVRHLRLTPRGQELCAALVARHEAIQAKLEERMGHGQVAEFLRLLTLYC-------- +>tr|A0A1U6J3D8|A0A1U6J3D8_9MICC DNA-binding transcriptional regulator, MarR family OS=Arthrobacter sp. P2b GN=SAMN06272721_12259 PE=4 SV=1 +--------------------------RMFAAFHRrFADSGLTPAAYATLATIDRNPGVRQGRIAEELGLQNSNMVNLIKSLVERGFVERHRSASDNRVFTLTLSSAGKLFIEKMNERALALDAEYTRSLSDEERRTLIELLGKMI-------- +>tr|A0A1V4IFL3|A0A1V4IFL3_9CLOT Multidrug resistance operon repressor OS=Clostridium chromiireducens GN=mexR PE=4 SV=1 +----------------------------------LSDRNMSFSDAMVLIYVSANPGTIQDDIGSNLSIDKSVVARSIKSLEALGLLTRTEDLSNQRVKKVYTTEAAKEFKTYWNKIISQWNKTILADLTPEERSMVIYANYKIKVSAI---- +>tr|V4NPX8|V4NPX8_9CAUL Uncharacterized protein OS=Asticcacaulis sp. YBE204 GN=AEYBE204_18540 PE=4 SV=1 +---------------------------------RLRDLGVSESGWMTIALIAKSeTPPSQSDLAQALSVEGASMVSMIDRLVKLGLVERVGSEADRRVKHIVLTDDGHKVFARVKQEADAFRAETVSRLDPEKLAVAADIMEQLQNFIN---- +>tr|A0A176TIB8|A0A176TIB8_9LACO Uncharacterized protein OS=Pediococcus parvulus GN=A7K95_08110 PE=4 SV=1 +-----------------VNHQLHVLANMSSRRFSeaflnN---DITGKQGGILHYLLWNAgKREiyQRDVekNFSI--RRSSVTSLLKKLEDKQYITRESVEGDARLKQIVLTPRALKLRKSVIQGSYDFEDKLLQNVSAADIEVWQKVTKQMIANLSE--- +>tr|A0A1C5VQU5|A0A1C5VQU5_9FIRM Salmolysin OS=uncultured Roseburia sp. GN=slyA PE=4 SV=1 +-----------------ICRNLKIFDCMMNDHRNkdmegS---GMTGRQFEVLSYLVE-HqNENvkQVMIekDFQL--SNPTVSGILKRLEQNGLICRISEDTDKRCNRIVVTKKAQRALIQAGEKWEILEEKLFDGIAKEEEQIFDEILGKLCRNITK--- +>tr|A0A1T4XPX6|A0A1T4XPX6_9FIRM DNA-binding transcriptional regulator, MarR family OS=Gemmiger formicilis GN=SAMN02745178_02161 PE=4 SV=1 +-----------------FGALLNQTSRLIRRALDarinaEVSSELSGVRGMVLGDIVRAeRqGRDvyQRDIeqWFNI--RRSSVTAMLQGMEQDGFITRSAVAKDARLKRLIATEKGRACHKQIEASIARFEDDLQSGIDPQQAAAARAVLEQTLRNAQH--- +>tr|I7HEC7|I7HEC7_9HELI Putative MarR family transcriptional regulator OS=Helicobacter cinaedi CCUG 18818 = ATCC BAA-847 GN=HCBAA847_0432 PE=4 SV=1 +---------TQYLIGHHIGRTARSFQEFFIK--ELKAHNLSFEQGVILFMVSENPKIHISHIARELHKDKATISREANSLVNKGLFVKTQDSCDKRTTLLVLTPNGENALNLIKDKIKKLESLLFSRFSQDEINTCLNVLENMRLAI----- +>tr|R6PA12|R6PA12_9FIRM Uncharacterized protein OS=Eubacterium sp. CAG:274 GN=BN582_01227 PE=4 SV=1 +----------------------------------LIDVNISFMEGLMISYAGNKPDQNQETLASLSGVDKYRTAKFLSSMEERGLIVRKANPENKREKLVALSEDGKEIYEKFNKWSEEWRELCFKDFNKDEINIFMGLLDKMIKNLE---- +>tr|A0A1V0LQP4|A0A1V0LQP4_9FIRM MarR family transcriptional regulator OS=Eubacterium limosum GN=B2M23_04685 PE=4 SV=1 +----------------------------------LGGMQLNNTEQSILLYLKHNDGVNQHAIARFFQFNKTTVAKTLSALEDMGLIKRETNCESKREKRVYLTEAGNKAVVLIKESRRQLEEEVMAEFTEEEKALFDELSERIAVKVW---- +>tr|K2E8X4|K2E8X4_9ZZZZ MarR family transcriptional regulator OS=groundwater metagenome GN=ACD_18C00328G0001 PE=4 SV=1 +-------------------------------------NSLSYIQFQTLSFLLKYNSPTMREISEYTHITAPSTTILINNLVRMKLVLRIHDEFDRRLIRLIITTSGKEELEKGVLAVKKHLKNVFSKLSKKDRHDFMRVLIKLSNFFNQV-- +>tr|A0A151EKN3|A0A151EKN3_9EURY Uncharacterized protein OS=Thermoplasmatales archaeon SG8-52-1 GN=AYK20_06260 PE=4 SV=1 +-------------------------------------FGITGVQLMTLHFIKHNNNCKTSEIANFLSVSAPDATRIVETLVKKGFVERINDEKDRRIIRLLIKEEGKKVVETIKQELALSFSKILEKINEEDAKALLRGMKALSNALKEL-- +>tr|B8FL86|B8FL86_DESAA Transcriptional regulator, MarR family OS=Desulfatibacillum alkenivorans (strain AK-01) GN=Dalk_3031 PE=4 SV=1 +----------------------------------LEPMGLTGAQANALGILFRKKNLSLGEFAARAGIGKAAAVSMIHRLTETDFVTAVPDPNDARKNIINVTDKAIKVIAPAMTIVRHLESTVEEALGEDVLKTLVDALKVVR-------- +>tr|A0A0C1S8D8|A0A0C1S8D8_9ACTN Uncharacterized protein OS=Streptomyces sp. RSD-27 GN=PL81_27605 PE=4 SV=1 +----------------------------------LRPFKINVPQYGVLFELSRQSGLSGAALARRCMVTPQTMSSVLSTLEGRGLVERTPHPIHLQILEVRLTPAGKTLIREADVVIEEIEKLLDGCFAPGEARSFLEQLERCEKAVT---- +>tr|T4BE11|T4BE11_CLODI MarR family protein OS=Clostridioides difficile F501 GN=QOE_3967 PE=4 SV=1 +----------------------------------CQQYGLTLQQMHVLMELVRTPGLTAGQLSDRAGILRTNFPSVCRKLEDRGLIERQRSQTDRRSLKLRVTDEGRALLADVDGEV---QRRYGEAFAAEPPETFDAIIGGFRALAD---- +>tr|A0A229TC41|A0A229TC41_9PSEU MarR family transcriptional regulator OS=Amycolatopsis sp. H5 GN=CF165_13450 PE=4 SV=1 +----------------------------------LRKLGVSGSLYAVLANLQVTPGLTGAELARVVGVTPQAIAALVSKLSGRGWIERRSHPRHGNVQELHLTDRGRGELAGANRLMADLDGYLQQSLGDENYRQLRRLLGEVVELLP---- +>tr|K5AD31|K5AD31_PAEAL Transcriptional regulator protein OS=Paenibacillus alvei DSM 29 GN=PAV_1c01990 PE=4 SV=1 +--------------------------------------NVNMTQFAVLDLLFRNGSMKVTDVAKELRLTPGAVTGITDKLTQMDYVARNRDKLDRRINYLELTEAGRQKVKAVEIQREFVFARYFEGIPDEDLLHFLHICQQVNLNLD---- +>tr|A0A0V8M571|A0A0V8M571_9CHLR MarR family transcriptional regulator OS=Dehalococcoides mccartyi GN=DA01_00045 PE=4 SV=1 +--------------------------------------DVPLAQMKSLFIIIGKGEMNLGALAQSLGVTPGDVTGIVERLVEQGLISRKPGAEDRRVTWLSATDKGHALVTNLVESKSEHMADILEHMSLDGLVSLEKGLKELISAIR---- +>tr|A0A0F5Z341|A0A0F5Z341_LISSE MarR family transcriptional regulator OS=Listeria seeligeri GN=UQ68_08520 PE=4 SV=1 +-----------------------IHQAISELS--TSTADISIEQFFVLREIAENDGIGASDLALCLLANKSAVTPKLKKLEEKGYIKREKNPTDKRAIILTITKKGNEVYQECEQKLENLVNDWLEILGEKDSEQFLNLYEKITKSVIQT-- +>tr|W7BRY5|W7BRY5_9LIST MarR family transcriptional regulator OS=Listeria floridensis FSL S10-1187 GN=MFLO_13183 PE=4 SV=1 +-----------------------IDQAIEQVD--FYGKRISMEQFFMLRELCReENGVSATQLSCRLNVNKSAVSAKIKNLEEKGFLVRSQNPFDRRAVVLHVSDQGREIFKVCEKAMQDLIGDWLRRFGKENSEMFMTLYDRLIDLVIVN-- +>tr|R7FRU3|R7FRU3_9CLOT Transcriptional regulator OS=Clostridium sp. CAG:288 GN=BN588_01403 PE=4 SV=1 +-----------------------LIQKIYTQGELNPFIQLVQSDSRILLYLFYHPSCHPSDISKSLNMSRPNVTANLKNLEDNEMIVRTLNAKNRREIYVTLTAKGMQEFNNRMSKIIGLFQDWLKLLGEEETEHLIRILEISSDMNNIG-- +>tr|A0A069RIB3|A0A069RIB3_CLOLI Uncharacterized protein OS=[Clostridium] litorale DSM 5388 GN=CLIT_8c00540 PE=4 SV=1 +-----------------------DYNYFINKR--LRELQIKKNDVKVIKNINQNHGISQNEICVLLKEDKVTVAKSVKKLEALGYIKRTNENADKRIVTLYVTEEGQGVRRKIMKIFEDLKTIFMKDLSPKEQEMAVALLAKMSKNMHDE-- +>tr|A0A1W9VTC4|A0A1W9VTC4_9SPIO Uncharacterized protein OS=Spirochaetaceae bacterium 4572_7 GN=B6229_02995 PE=4 SV=1 +-----------------------QIN-----Y--GDDESISFSEAQVIEEIIRHKDSNMTDLSKELGVTKAAITKTMKKLENKGFITRFKQEFNKKEIFVSITKKGHEIYKHYQEYMyTNLFGELFQmfsAVDPSHAEMIFQFFNSVDKSLSKI-- +>tr|A0A0Q7SCE6|A0A0Q7SCE6_9BURK Uncharacterized protein OS=Pelomonas sp. Root1444 GN=ASD35_25540 PE=4 SV=1 +-----------HTLGYAIARAAVTTNQLFSQGVG--EpLGVRPVEFTLLQLIFSNRNTTQKRLCDLLRVPAPQMTLILDRLQERGWVERERDANDRRALHLRLTAEGERLAEESLVALQVAEQALDRVLSSGERLLLQELLAKVAR------- +>tr|A0A1B1NDX9|A0A1B1NDX9_9MICO Transcriptional regulator, MarR family OS=Serinicoccus sp. JLT9 GN=SGUI_2230 PE=4 SV=1 +-----------RRAGFLLATVGRRTDAAWGGFLR--SRGMTNAEFAALAVLVDGS-ASQVELARQLAIDARNAGATVRKLRERGWLSSAADTTDRRRVVLTLTPDGQRAWDDLQAELRGSRSDYFGALDDPERAELERLLNKLNDA------ +>tr|A0A1Q9ATP7|A0A1Q9ATP7_9RHIZ Uncharacterized protein OS=Rhizobium oryzae GN=BJF93_17065 PE=4 SV=1 +-----------NCLVLNTVAAARTLVRKGDARFK--PFGVTVQQFSLLAAIRFNPGEPVMSLAQKIQLDRTSLTRNLDLLERKGLVQRAADAvGNARI--CELTKEGSVLLDQLLRVWQQAQSEISQGFTEDEADTYLRLAKDFADR------ +>tr|U6S1U2|U6S1U2_ENTFL Transcriptional regulator, MarR family OS=Enterococcus faecalis VC1B-1 GN=D350_01616 PE=4 SV=1 +--------EFEIKRGETMNQQQEALKAYIGLLRtshrleqlakqDVTCYDLNITEFSVLELLLHKGPQTIQKIKEKILIASSSTTYVIDQLHKKGYVTRTPSEKDRRITYVELTEAGKTLIEEIFPTHAKRIAEAFEQLSSEELTLLQKTLRKITNE------ +>tr|A0A1B8XBQ6|A0A1B8XBQ6_LEPIR MarR family protein OS=Leptospira interrogans serovar Copenhageni/Icterohaemorrhagiae GN=A9P81_1769 PE=4 SV=1 +----------MGTHYKGNSRETAVLNAFIKLSRcsdsirqleekVFSKYGLTTGQFGCLETLLHLGPMCQKEIGQKLFSCEGNITQIVDNLEKRKLVQRVRSEEDRRYIIIHLTSEGKKLIQKAFPDLLNSLVHKFGNLSENQLLDLGDFCKEIGLK------ +>tr|A0A1F8IJA1|A0A1F8IJA1_9PROT MarR family transcriptional regulator OS=Caulobacterales bacterium RIFOXYB1_FULL_67_16 GN=A2352_01930 PE=4 SV=1 +-----------------------ALQLSLDIYAEEMGADgLTQRQFAVLEAASLKAGLTQTELVRMTGIDRSTLADLVTRMTTKGLLERERSTLDARAKAVRLSAEGAARLEAARPKVETADKRIMALLPKGQREVFLSQL------------ +>tr|A0A1K1RGR6|A0A1K1RGR6_9BACL DNA-binding transcriptional regulator, MarR family OS=Paenibacillus sp. UNCCL117 GN=SAMN02799630_06089 PE=4 SV=1 +-----------------------------ASYAKLADSRISSSQYFILQALVHEGPLTCSHFAHVLDVTLSAVTNLSNKLVKNGYVERIPSETDRRQVYLRITEQGREMERRLLERYELLTEGLWEEFSGPEVELLIAAYKKMIAHV----- +>tr|G8P1S4|G8P1S4_GRAMM Regulatory protein MarR OS=Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8) GN=AciX8_1558 PE=4 SV=1 +----------------------------------LQPLGITAAQLRLLRAVQDAPGISGAKLADICSVTPQTGQQLMMKLESNGWITREKNPANERVLLARLTKKGEKMLQHARAIAEVAHHKLWQRIDPAKLAVFDEVLAISCEN------ +>tr|A0A0J8Z1F3|A0A0J8Z1F3_9FIRM Iron dependent repressor OS=Coprobacillus sp. 8_1_38FAA GN=HMPREF0979_00850 PE=4 SV=1 +-------------------------------------------------ELEEKNQKVKvSDVSEVLNLPRPGVTRTIHAMEEKGYLKKETAKHDGRVTYVTVTKEGKMIFEKYNKDYFQKLALCLNHVSNDEADCMIQTIEKFYE------- +>tr|A0A1X7FTA2|A0A1X7FTA2_9RHIZ DNA-binding transcriptional regulator, MarR family OS=Rhizobium oryzae GN=SAMN02982989_0783 PE=4 SV=1 +----------------------------------LAPMQMTGIQYTVLSVIGSRDGLSSAELSRRFFVTPQTMNELIGGLQRRNLITRKEDPANRRILRMSLTNEGKRMIKACDAAADIIERDVFSFLPQESYEQFRDLCRQIARNLR---- +>tr|A0A1M3P5S2|A0A1M3P5S2_9SPHN Uncharacterized protein OS=Sphingobium sp. 66-54 GN=BGP16_15100 PE=4 SV=1 +------------------------------------DAGHSQVRWEILHAISVDSGqCTLMEVAGRVGLEAPSIVGAMAKLEAGGFIERRQDGNDRRSRLIFLTDKGRAAVTAMAAVVKEQRERIWQGIPDADIDAMLRVLSHLRSRLLEA-- +>tr|A0A0S3PY08|A0A0S3PY08_9BRAD MarR family protein OS=Variibacter gotjawalensis GN=GJW-30_1_03390 PE=4 SV=1 +---------------------------------ALAAHDLNAPQYSVLEAIQNNPGATNADLAREALVTAQTMGGIVQALELANCVERVP--GEARRISNRLTRTGADILRRARRDVQKLERDMVDGIDKSKLESFSKTLSAMTDKL----- +>tr|Q2LXK3|Q2LXK3_SYNAS Transcriptional regulator, marR family OS=Syntrophus aciditrophicus (strain SB) GN=SYN_00342 PE=4 SV=1 +--------------------------------------NISHAEYRALQAALDCDICSMQDIAKSAGVTKSGATRIAKRLEGKGLAKRQQDRKDGRICCVTLTEEGRTLLKRIEDRLLNKMRKILVNMDTTVREILILSLSSFVQSA----- +>tr|A0A1V5XYU3|A0A1V5XYU3_9FIRM Transcriptional repressor MprA OS=Firmicutes bacterium ADurb.Bin182 GN=mprA_3 PE=4 SV=1 +--------------------------------------DLSLVEFMALKKIQESNEITIQEVGNAINFTKSGASKIIDRLEKKGYVVRMNSPADGRVCCVLTTDKGKETVAGIMENYTLYLDDVLKGIDPQQIGQIRETLIMLVDTL----- +>tr|A0A0M9VH75|A0A0M9VH75_9FLAO MarR family transcriptional regulator OS=Flavobacterium akiainvivens GN=AM493_03885 PE=4 SV=1 +----------------------------------LDPLNLTQTQFVLLAALGwlsRENdNVTQVDIANQGNADRMMVSKVLRTLEEKKFISRHEHKTDTRAKVIKLTDEGAKVLQEALLAIENADVEFFSILGTDKLSVFNVNMV----------- +>tr|A0A0Q4S9Q7|A0A0Q4S9Q7_9FLAO MarR family transcriptional regulator OS=Flavobacterium sp. Leaf82 GN=ASF10_07455 PE=4 SV=1 +----------------------------------LEEHNITHSQFVLMASIHwltLHAqEVTQIILSAHTKIDPMTTSTVLRTLQQKSLIARKEHATDTRAKVVVLTDLGKKIIKKAIVTVEDFDRKFFAVTGV-NTKDLNQNLI----------- +>tr|Q8TU97|Q8TU97_METAC Transcriptional regulator, MarR family OS=Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) GN=MA_017 +----------------------------------LAQYRMGWVHYAILMSLFDHEGCSQESLARSGEFNKTMITRSILRLEEEDIIYRKIDLDDKRVKRLYLAKKGKKLRYKMEKIRLELNILLLKGFDSEELASVTEIMRKIALNASR--- +>tr|A0A1M6JNX9|A0A1M6JNX9_9FIRM DNA-binding transcriptional regulator, MarR family OS=Dethiosulfatibacter aminovorans DSM 17477 GN=SAMN02745751_02676 PE=4 SV=1 +----------------------------------LKAINMTTLQSIVLINIKRHEGVNQNELASVVGIDKASVSRVIRDLENRNLLFKEIDQSDRRHFRLFLTDKGKEEVEKSVEIQMRIWLDCMKEINSEELNISKEMMIKLYSNINE--- +>tr|A0A0R1ZUN2|A0A0R1ZUN2_9LACO MarR family transcriptional regulator OS=Lactobacillus malefermentans DSM 5705 = KCTC 3548 GN=FD44_GL000493 PE=4 SV=1 +------------------------------------SYGLTGVQLSTIDFLARQKNQsvLQKdiEVEFSIRRS--SATTLLQRMAQKELISLSKSAADERQKEVHLTAKSQDLIQVVGDYLEVQQNSLEANFTPTQLRAFSSILTFLKKD------ +>tr|E6LD73|E6LD73_9ENTE Transcriptional regulator OS=Enterococcus italicus DSM 15952 GN=rmaI PE=4 SV=1 +------------------------------------QYQLTGTQMSILNYLYEHSGEdiSQKdlVTEFGVKGS--TMSVIVHRMEERNLVTRQIV---GRQKYLNLTPNAQTYITAIQNFFQKDNERLIAGFDTNELAVIAKFLQQIGGK------ +>tr|A0A1U9NDK1|A0A1U9NDK1_9GAMM MarR family transcriptional regulator OS=Cellvibrio sp. PSBB023 GN=B0D95_17460 PE=4 SV=1 +----------------SLRRVIRAIDLHSRQLV--KTASVTGPQLRLLQLIRSQQGGTVKELADAMSLSQATVTSIMDRLESRDLIARVRSQTDKRKIHPQLTASGNALLDTAPTPLQDSFVRKFDQLHTWEQHMIIASLQRVAEMMD---- +>tr|K6T1R9|K6T1R9_9CLOT Transcriptional regulator OS=Clostridium sp. Maddingley MBC34-26 GN=A370_03930 PE=4 SV=1 +--------------------------------------EVTLAQCHALVEIGRAKNISLKDLSTLLILDISTMSRTVDSLVKKEFVYRATSEIDRRSVDIKLTEKGLNLFHDIEKKMNEKYKNIFNQITSEDQAIVFNGLNIIIEAITKN-- +>tr|A0A1D9BI60|A0A1D9BI60_9NEIS Uncharacterized protein OS=Jeongeupia sp. USM3 GN=BJP62_17485 PE=4 SV=1 +--------------------------------------AINLSQNSRILEMmYRVGPMTQSTLGQILNFEKSWISRMVDQLVAEGWVERTPNPQDRRSNILVLTAAGQTHAKDIGTMFDKHARDVLDRVSDEARDELLRAMTHLGNALPPR-- +>tr|A0A1R1C902|A0A1R1C902_9BACL MarR family transcriptional regulator OS=Paenibacillus sp. FSL H8-0548 GN=BK133_30500 PE=4 SV=1 +--------------------------------------DISLVQSHIIYEIDRKHNPSIQQVADSLSIDITTFSRQVQSLVKMGVVKKTPLPEDRRIYILSLTTEGKYISTVIDAQMNDYLKEVFSHMSEFERDMVINSIKLLNESMAKS-- +>tr|A0A1S1BTL6|A0A1S1BTL6_9LACT Uncharacterized protein OS=Aerococcus sp. HMSC035B07 GN=HMPREF2705_01445 PE=4 SV=1 +---------------HLIFQLANLQKKYLFER--LKEVDLNPIQAQTLHYIYREAGPIQRSLATYLGKHEATISNILNVLEDRGYLYRQTASDNSRQKQIFLTASGHEQVEKINGIFKDLEAELCSDLSSQDRAKVLQVLTDQRD------- +>tr|A0A1Q9NNI4|A0A1Q9NNI4_9ARCH HTH-type transcriptional regulator Hpr OS=Candidatus Heimdallarchaeota archaeon LC_2 GN=hpr PE=4 SV=1 +---------------------------------------LFAGQEMVLTRLAKKPNIVLNELAGFLKTKPPTVTKVTKGLQDQGFLIMTKDEKDKRVTRVNLSRKGENLQEEIARIWGIIEKETFKSFSIEERVIFKRLMQQIIENLES--- +>tr|J2YKG0|J2YKG0_9PSED Transcriptional regulator, MarR family OS=Pseudomonas chlororaphis subsp. aureofaciens 30-84 GN=Pchl3084_3461 PE=4 SV=1 +--------------------------------------NLAQTPFFVLLLLKRNpgG-LSIGALADGVAVASQTMTRAIKQMEAAGLCTKHPDPDDGRYWIVRLTPEGDSTLGRVLPKHYEWVARFMRHFNEDERELLVKLMMRVAPALRT--- +>tr|A0A1F3TSK9|A0A1F3TSK9_9PROT Uncharacterized protein OS=Bdellovibrionales bacterium RIFCSPHIGHO2_01_FULL_40_29 GN=A2622_13935 PE=4 SV=1 +--------------------------------------GLSQARFLALIILEREnmKQQMPVEIARKMGTTKKNTARLLAFMEEDGLITIKPHEIDGRATIVKITLKGSKRLNDVLPKYYKIMNSMMKNISEKSKSTLIQILNQIET------- +>tr|A0A1N6LUB5|A0A1N6LUB5_9BURK DNA-binding transcriptional regulator, MarR family OS=Burkholderia sp. GAS332 GN=SAMN05444172_8813 PE=4 SV=1 +-------------------------ARSVTKALKPFDVNLT--CWRILALLHRMGSLTTTELSDMSAIERSALGRTVDTMQASGLIRKVGRSDDQRMQDVEILEAGTRLYLEILPIVKRINDHAIWNVSAADLDRCISILKDVRSNLS---- +>tr|A0A1Y1T6H0|A0A1Y1T6H0_9FLAO Transcriptional regulator BlaI/MecI/CopY family protein OS=Zunongwangia atlantica 22II14-10F7 GN=IIF7_03951 PE=4 SV=1 +----------------------------------LAKLQLSYPEYLVMLMLWENN-eVNIGQIRRQLYLNKESLLPILNALQQKSFITLQDQDPDTLEAKVSITKTGLALKTKAKRIPFSLSR--VLNTPVEELGSMQLLIKNFLSRFEKK-- +>tr|N6W5U0|N6W5U0_9ACTO Uncharacterized protein OS=Actinomyces cardiffensis F0333 GN=HMPREF9004_1356 PE=4 SV=1 +-------------------------------------FGLTLSDYNVLLALWESPHHAlrMGELAQRVIFSPSRLTYITTHLERDGWIEKTSVKEDRRSSCACLTSQGEEVVKKANALHQgMIREYLLEGFNEEEICDIVRIVQGFGDKLS---- +>tr|A0A1A0QR96|A0A1A0QR96_9MYCO Uncharacterized protein OS=Mycobacterium sp. 852014-51730_SCH5271717 GN=A5762_12855 PE=4 SV=1 +-------------------------------------HDLSAMDLRVLSVLLKAPTGFvrMGDLAKEVGLLPGHLTKRVQRLEERRLVRREKYPHDRRVVMAAITDEGRTIAAKAAMTIArGVRADLGGSLSSAKVSIIEKNCGRISAQFK---- +>tr|A0A0J0UY69|A0A0J0UY69_9ACTN Transcriptional regulator OS=Actinobacteria bacterium IMCC26207 GN=IMCC26207_10683 PE=4 SV=1 +-------------------------------------CDMCLSEFEILLHLSESPTKSrrMTELAELARLSPSGLTRRFDLMLKRGWVNRERCDQDRRGVTALVTKEGLKQVQMATPVYLrVQDALFFSQLVSEQLAALQGVSESIARAAE---- +>tr|A0A1S2IR30|A0A1S2IR30_9MICO Uncharacterized protein OS=Curtobacterium sp. MMLR14_010 GN=BIU98_08130 PE=4 SV=1 +-------------------------------------AGISTPEFEILIGLHRQVDHRlrVRDVAAGIGWEKSRVSHQVTRMVSRGLVERTDCPTDGRGSWVVMTPDGRRAVLAGIRAHTaALEQLFWRPVADDA-DTLRSVSARLQSALG---- +>tr|A0A0S2F6I6|A0A0S2F6I6_9GAMM Transcriptional regulator marR/emrR family OS=Lysobacter antibioticus GN=LA76x_1016 PE=4 SV=1 +------ELDLEHFL-P---YRLSVLSNRVSSAIarvYSERFALSVTEWRVMAVLGRYPGLSANEVAQRTAMDKVAVSRAVARLIEAGRLERDTHDDDRRRSVLQLSLDGYKIYDEVAPMALAFEQRLLIGIEAPEREALFRLLDRLDELEM---- +>tr|A0A1M7JET2|A0A1M7JET2_9RHOB DNA-binding transcriptional regulator, MarR family OS=Roseovarius litoreus GN=SAMN05443432_108153 PE=4 SV=1 +------ALILHDFV-P---FLLNEAAETVAKRFssfYVDRYSMTRSQWRVMANLGRFGKLTATEISHHGRLEKSVVSRAVFAMEKRGWLTRHAKAGDRRVELLSLTGDGQEIYMVLVHEAKAFDDELRSFIETAQVEGFVAVLRRLNDEAE---- +>tr|A0A1E5K837|A0A1E5K837_9MICC MarR family transcriptional regulator OS=Arthrobacter sp. D4 GN=A5N13_09045 PE=4 SV=1 +----------------------------------LSDFRLRERSFSVLTLACSGLEATQREIAEFLDLDLNQVAGLVDDLEHRGLVERVPGQRNRRSRAIVSTQEGRRIHNKIRAELDVCEQQQLARLCDDEVVHLKQLLRKALW------- +>tr|A0A0R1FVD3|A0A0R1FVD3_9LACO Uncharacterized protein OS=Lactobacillus kunkeei DSM 12361 = ATCC 700308 GN=FD43_GL000325 PE=4 SV=1 +-------------------------------------SEISWAEARILMDVGYMKNPTPMKIAINLDLDKSYVSRVINKLNNLKYIEKKDTKKDKRTKLLYLTNTGKQVVEQLNINSDKQIQLIIDNLSNEEQESFYQSINTLNQL------ +>tr|K6SX39|K6SX39_9CLOT Transcriptional regulator OS=Clostridium sp. Maddingley MBC34-26 GN=A370_05447 PE=4 SV=1 +---------------------------WSSVFLDYS-----KNEILAMLLIYRKNKVNMSEVAEYINAPLNTATGVISRLEKKNIAERTRDNEDKRVVMITLTENGREFILEEKKQIEYYFKEVYKSLTKEEINAAMSIVNKVVTVLK---- +>tr|A0A0L6JVS5|A0A0L6JVS5_9FIRM Transcriptional regulator, MarR family OS=Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933 GN=Bccel_5096 PE=4 SV=1 +---------------------------IINIDLELS-----KSEIVLLLQLEKQGELMMSKVSDSLNVPMSTATGIVERLVKSSYVIRDKSETDRRIVVIKLTDKGKSLVSKIHTIALGYIDDICNELEPEEIQMIIKIFYKVIDVVE---- +>tr|A0A0M4G7W8|A0A0M4G7W8_9BACI Uncharacterized protein OS=Bacillus gobiensis GN=AM592_06060 PE=4 SV=1 +---------------------------IDETLKKVT-----RSELIALIILKQRGEATMSQLASEMGLQKSTLTNIRQRLTKHGLIQHYRDANDQRIIRISLTEDGEEFADRVLETMSRVLQKIKDALTSDELEQLINLLLKVAKVVQ---- +>tr|W7QEQ8|W7QEQ8_9ALTE MarR family transcriptional regulator OS=Catenovulum agarivorans DS-2 GN=DS2_04320 PE=4 SV=1 +-----------------------------KAVFKQTGYEITP--EAyFLLNLIPESGIEQGALVKKTGKDKAAITRLLDWLSGKNWIIRRVVPDNKRKAIIKISPQGKEVLVALNKALSNISQPMMKGISKNEHMVLMNaikqlddNLL----------- +>tr|A0A1C0Y6W6|A0A1C0Y6W6_9BACL Uncharacterized protein OS=Caryophanon tenue GN=A6M13_05725 PE=4 SV=1 +----------------------------------CATRKMTSMQFLMLRYIHQSKSCTSMDIVKAWNVEKPTVSEHIRRLHDKGWVAITQGA-DRRVKNLSLTTEGIAVYEDIIIEVERLQQEVTAIFTEDELDVFTRFVAKLEQQ------ +>tr|A0A243INS8|A0A243INS8_BACTU Uncharacterized protein OS=Bacillus thuringiensis serovar yunnanensis GN=BK708_39455 PE=4 SV=1 +----------------------------------LTELELYSSQFVLLNALRRIGPCTQSDLSKYLSIEPAAISNIIRRLEKGDWISKTKGT-DRRKKIISLSTKAQKNTESLDKVDQDMLSQMYQGISLDKLQISLETLLQIEKN------ +>tr|W6TRA5|W6TRA5_9SPHI Uncharacterized protein OS=Pedobacter sp. V48 GN=N824_26720 PE=4 SV=1 +--------------------------------------KFTLPEVRVMYEIHHaKKVSAKA-ITELLDMDKSYLSRVLLSFEKKGLIEKTSDHADARIQVIALSATGAKEYEKLNKASDNQIADLMKRLNNEEIKELILHMGAIQNILSKIS- +>tr|U4V0H6|U4V0H6_9RHOB Transcriptional regulator OS=Rhodobacteraceae bacterium HIMB11 GN=HIMB11_01227 PE=4 SV=1 +--------------------------------------GLVRAEYILLACLSHYDELTARDVAQISMRPRNTISRAVHRMVAEQLIERRHNRVDKREASLTITKKGQRLHERIAAYLTQRQEDVFAGLNAQERQELSKLLRKTAL------- +>tr|A0A118E5D0|A0A118E5D0_BURVI MarR family transcriptional regulator OS=Burkholderia vietnamiensis GN=WJ03_29660 PE=4 SV=1 +--------------LQQFGRTYRA---FMSAFETHVGQPMP--RWRIMVALHTLDgQASQKKLVEVLRIDPGALTRQLKSLDALGWIERASDARDNRVTNVTLTAAGRAAFDACLPRRKAFLDRTVAQLPDDVLTALSGALAMLESRIAEV-- +>tr|R6K9W9|R6K9W9_9FIRM Uncharacterized protein OS=Eubacterium sp. CAG:248 GN=BN561_00696 PE=4 SV=1 +------------------GELIKRLNDILGTCANkelkSDDMTASQIKMliiisetknesITLKELEKHFGVAQATV-----------AGIVARLEKKAMIESFYEPDDKRVKHVKLTDKGRGVCKHAWANMVKKEEWFLSSLDDDEKEELWRLLQKIYDNMRRNE- +>tr|A0A069CSD7|A0A069CSD7_9LACT MarR family transcriptional regulator OS=Weissella oryzae SG25 GN=rmaE PE=4 SV=1 +------------------------QRQQYDQLS--QEYDISRTQARTLSYVAKNPGLNQKQIAEYLSVRGSSTSDLLKDLEADDYIERYASRgTKDRSKKIYVTAKGLKLIERLDKLFIDIDGKLIAGISKEDTVNLKRILSMMDNFL----- +>tr|A0A1V3Y594|A0A1V3Y594_LACGS MarR family transcriptional regulator OS=Lactobacillus gasseri GN=BXT97_04900 PE=4 SV=1 +------------------------ENLLINQRL--SSINLRMTHAHALRYIQKHPGCIQKEVAEYLFYQPASFTNVVKLLEKRQMIERRPDPKNGLKKQLFLLPAGKDVLDQVNQAFEEVNQ-LVGTVKSDTLTKLEEISNNLEKQV----- +>tr|A0A0S2HVI7|A0A0S2HVI7_9BACT Organic hydroperoxide resistance transcriptional regulator OS=bacterium L21-Spi-D4 GN=ohrR PE=4 SV=1 +--------------------------------------GISIPQLLCLQFLHESDNFQAthKAITRYLELNSSTVTGIINRLQKKGLVARLPKQQDKRTTYIALTSTGEQMLKNSPQLLHTRLSDKLDNVSAESIEVISDSLDKIIS------- +>tr|D4H7F2|D4H7F2_DENA2 Transcriptional regulator, MarR family OS=Denitrovibrio acetiphilus (strain DSM 12809 / N2460) GN=Dacet_1179 PE=4 SV=1 +--------------------------------------NVTLPQMLSLYEISQHDSMNLTELTRSVNLNNSAITGIVDRLEAKGFVNRVKKAGDRRTIYLEITPAGKEYTALLTKILEDDCFFDEKKLGKENVNDIFQSLAKITN------- +>tr|K2N7Y6|K2N7Y6_9RHIZ MarR family transcriptional regulator OS=Nitratireductor pacificus pht-3B GN=NA2_05266 PE=4 SV=1 +------IYQLRDGLGFRMSRTARVMERHYEQL--LAEIGLSRLMWCVLVMVGSYgIAAPS-AMAEFLSVNRTAISRVLREMEKQGLVLRRQQDGDRRGRDIGLTELGQHKLEVFLPKATLTTEHFKSKLTEDEFEMLKTVLDKMME------- +>tr|A0A1X7EEW8|A0A1X7EEW8_9DELT DNA-binding transcriptional regulator, MarR family OS=Desulfovibrio sp. K3S GN=SAMN06295933_2862 PE=4 SV=1 +-----------------------------------SALGITYCQVGFVMTALNHPGWNQEQLSHFLVVDKGSTARSVAKLIKLKFLYREENPQNRREKLVYPTEKAEEIREDLHKALQSANQLMMSNLREPEKVVLLEMMKRMIDTGRNSL- +>tr|M3TEE9|M3TEE9_9ACTN Putative MarR family transcriptional regulator OS=Gordonia malaquae NBRC 108250 GN=GM1_012_00290 PE=4 SV=1 +-----------------------------------AANGLTFTEYSLLRMVDDRPGMNAAELASTAMIDKSTASRQLGALRDRGLLARAADGRSARGQRLELTDLARTTLSDIASASEAAISARLTDWPADDVATFAALLHRYNSS------ +>tr|A0A1C2BU11|A0A1C2BU11_9PORP Uncharacterized protein OS=Macellibacteroides sp. HH-ZS GN=A9168_10855 PE=4 SV=1 +------------------GMASLALSKALNAALIENNIDLPHSQFVVLRILYFHDGMSQLDIANMVSKDAAAIKRTVDNLENKGLAVRKQV--RTLKNSVCITDKGREFMPQVLKIADKIIEEALNSFSEESREQLFSMLKMIYQNIE---- +>tr|A0A0D6ZAX6|A0A0D6ZAX6_9BACI Uncharacterized protein OS=Bacillus subterraneus GN=UB32_09825 PE=4 SV=1 +-------------------------------------EKITIPQFIVLQTISKEKRCNLKDIVNELGTTTGAVSLLIDKMTKLDYVLRERDTTDRRLIWISFTKKGAELYDQITQKRNEVLEHYFSKWTEEETKTFMNLLTKAF-------- +>tr|A0A081B7W7|A0A081B7W7_9RHIZ MarR family transcriptional regulator OS=Tepidicaulis marinus GN=M2A_0634 PE=4 SV=1 +------------------------------------------GHQRLIRQLLLKDGQTQTELATAMHIHKVSVGLYINDLVEMGLVERRRHPKDGRAYCIHLTEYLHRFRPEGERVFAEIHAHAIKGLPTEEYRMLLQAMEKI--------- +>tr|A0A0F7FXJ3|A0A0F7FXJ3_9ACTN Transcriptional regulator, MarR family protein OS=Streptomyces xiamenensis GN=SXIM_33160 PE=4 SV=1 +------------------------LNDRLLAEVAA-GTGVAASSFQVLWHLLAAPSRsaPMRELTETLGFSTAGTTKVVDRLAQQGLVDRRPSRTDRRVVYAVLTEEGAATATAAARAlAGALRRHLVAPLGPEGCAALLGALLTLEDAAA---- +>tr|A0A1F8S2V6|A0A1F8S2V6_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_69_14 GN=A2Z32_05235 PE=4 SV=1 +------------------------VSRRLDEELRA-EHNISFAEYDTLLTIAQAPGRriRMGQLAQEVLLSKSGVTRLIDRLVGDGLVERSACLADARGAEAVLTERGLSRLRAASRThLRGISEHFLAVVEPDDLDALERSMTAVVRQAG---- +>tr|A0A1Y6FHZ3|A0A1Y6FHZ3_9MICO DNA-binding transcriptional regulator, MarR family OS=Agreia sp. VKM Ac-1783 GN=SAMN06295943_3071 PE=4 SV=1 +------------------------LERRLGEQLR--PFGLTHGEYAILSILEANGPTgcRMTRLGELTQNPKTRLTQQVRRLEQAHLVSRAAVEEDARGVRVVLTDEGRRVLAAAAPGhSHVVRELVVGHIGEEDARVFARVLRDIENRLD---- +>tr|E6V159|E6V159_VARPE Transcriptional regulator, MarR family OS=Variovorax paradoxus (strain EPS) GN=Varpa_4922 PE=4 SV=1 +------------------------------------GFGITHREWELIAALRQIGEATPSAFAEHLQWDRVRTSRGLGSLSQKGLVERRRDAEDGRGVHVRLSPQGQQLFDDLFPRIARLDAELVAGIDDAQAGIFLQCLSRIEL------- +>tr|A0A1F5J6P5|A0A1F5J6P5_9BACT Uncharacterized protein OS=Candidatus Dadabacteria bacterium RIFCSPHIGHO2_12_FULL_53_21 GN=A3J42_03265 PE=4 SV=1 +----------------------------------------KSNQFIVLVAVAHLESPNFTKLADFVGIDQSTLARNLITVEKQKLVSVKTG-KNRREKLITLTKKGEHKIEKSFPLWKKAQGRLVGGIGAERWRDIQNELQDV--------- +>tr|A0A1C7G8E5|A0A1C7G8E5_9FIRM Uncharacterized protein OS=Lachnoclostridium sp. YL32 GN=A4V08_19600 PE=4 SV=1 +--------------FPNLGRCISLLDRLMRMYYdrGLADFEIGWGQQFYAEYIYDHPGATAQEMVEYIRIDKATLTKIIKRLSEIGYIEIVSDQTDKRVKHLYLTPRAIPA----VKRIKEIHqdfqSTLCSGISPQDMQLTEQTMEHMMENINK--- +>tr|A0A0J9E5E7|A0A0J9E5E7_9RHOB Uncharacterized protein OS=Candidatus Rhodobacter lobularis GN=AIOL_002884 PE=4 SV=1 +-------------------------------------RGLSIQEWRTLLVCTRLKDDHLRAIARWGVLDATHVSRATASLETKGLVRRYADPKDVRRKRIAITQAGEALVAEIWPEAQSLDAHIRASLGEAEYAALRTALMQILDT------ +>tr|A0A1C3STN7|A0A1C3STN7_9LACT Transcription regulator HTH, MarR-type OS=Lactococcus piscium GN=LP2241_20032 PE=4 SV=1 +--------------FQWTYREMQKqYDTLF------DSFGLTESRFLILMFLKRANENmlLPSQISEKLGASRPTVSKLLKAMEQKGLVEKHESVKDGRSSYFKMTIMGGDTLKTFMPHNFEAVKIIFGQLSKADHDSLKRLLAAINLGTET--- +>tr|A0A1D9PGX1|A0A1D9PGX1_9BACI MarR family transcriptional regulator OS=Bacillus velezensis GN=BK055_03960 PE=4 SV=1 +--------------LFDMAKKMNHvMEHYF------SSHGLSEGKFKILMFLFDAPGRslSPTELAKKSNVTKATITGLIDGLARDGFVNRSRHTGDRRKISIELTKEGKEKLMLFLPGHFSKISGVMENFTAEEKAAFTKMLEVLFDKILL--- +>tr|A0A0G9HVX9|A0A0G9HVX9_9XANT Uncharacterized protein OS=Xanthomonas hyacinthi DSM 19077 GN=Y886_35530 PE=4 SV=1 +----------------------------------LKPYGMNDSDFRTLMMLYSSEDGSAtpGELCALAEQKPTNMTRIANALAKKDLISRSHATHDRRQVLLRITPAGRRFVNRMPPPMFPPLVENFACFSSAERKTFEKLLKKLALHI----- +>tr|X1AKS9|X1AKS9_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=S01H4_01616 PE=4 SV=1 +---ISKIINLTRNFNKSMRHKF------HHS---IHDSGFTLPQLSVISMLEKHGEQKVSELSLKMGLSDSTVSGILDRLEQKDIIKRERTKDDRRVVRISLTGKSQKFCNDFRQKREEYFTQLLKSLSEQEIKDIIKGLEILNRVLAN--- +>tr|G0V3Q0|G0V3Q0_9CLOT Transcriptional regulator, TrmB OS=Caloramator australicus RC3 GN=CAAU_0090 PE=4 SV=1 +---ALEILEVLTSINKKVKRasKF------SPP---FKCKNKSQSAMKVMFHIMNSPPMTLKELSSLVGLANSTVCGIIDELEMEGYVKRIQDKDDRRRVIIIPTEKAELEKRNIENKFKEFLEYVLKDISAEDFEIIIKGLKKLDEIIKN--- +>tr|A0A1H5YQH5|A0A1H5YQH5_9BACL DNA-binding transcriptional regulator, MarR family OS=Paenibacillus sp. UNC499MF GN=SAMN02799616_02353 PE=4 SV=1 +---CVKVGELLRVIDTKHAKIV------NQH---YSPHNLTAPSINILLLLDKEGAMRVSDIGAALNMVDSNVSAICSRLENMELVERFRTKEDQRVVKIQLSPAAEEKMKDIIANVRDFQELFVKNSSREELEEIVRGLSLLERLLDN--- +>tr|A0A1C6FMD0|A0A1C6FMD0_9FIRM Regulator of autolytic activity OS=uncultured Flavonifractor sp. GN=mgrA PE=4 SV=1 +---SGDILMRYLKVTQHMSRLF------REH---FGRLHLTFPQALVLTVLGEEGPMPISALAERTGSANSTVSGIVDRLEKLELARRERSGEDRRVIYVAATARYEQLRKKTETDVGGYFSSVMDTLTEREKDQIIAALSRLDEALLA--- +>tr|A0A1R1BYI6|A0A1R1BYI6_9BACL Uncharacterized protein OS=Paenibacillus sp. FSL H7-0331 GN=BK127_16855 PE=4 SV=1 +---AMHISKSIHKLTRLYNATL------EKF---MKELNLTKPQGIIIGQI-YKEPKTIGQITEAVQLSYSTVSGIIDRLERDEWIQRVRDKTDRRVIWIQRTEKMEEIKNKVEFYHEQFFHTVLSDLDTDELDKIASSLDLLNSQLEK--- +>tr|A0A0D8CR60|A0A0D8CR60_9GAMM Uncharacterized protein OS=Thalassomonas actiniarum GN=SG35_23480 PE=4 SV=1 +-----------------------------------LAFKPAPMQLRAMRRIWSTGGSTLLDIARTLNRDKSQVKRLIDELCEVELVKREPNPADKRSKILKLTNKGYDFFETIEKIEAVFSEQLTAGIPAKDLEAFFRVSDRLSDNLREL-- +>tr|A0A1V5LW65|A0A1V5LW65_9BACT Organic hydroperoxide resistance transcriptional regulator OS=bacterium ADurb.Bin425 GN=ohrR PE=4 SV=1 +-----------------LGYRMKVLTLALSRRFseVLSPYEVTTVQWVALCRLWRQEGITTMEIGSHVDMVGGTLTGLLDRMEERGLVSRRVDEQDKRRILVFLTARGKELYQVLPPLALAITGDTTKGLKPSDIDFMKDFLQRMITA------ +>tr|A0A1B7LWD3|A0A1B7LWD3_9MICC Uncharacterized protein OS=Enteractinococcus helveticum GN=A6F49_15980 PE=4 SV=1 +-----------------------------------ANIGISAVSMRALGYIERHGPQRISHMASYESISQPAMTSAVNRLADDGLVVREPDPADARAQLVELTDQGQRMLDEYRNQVATVLQPMLENFAAADYAVIEHA------------- +>tr|A0A1F1UIN1|A0A1F1UIN1_9MICO Uncharacterized protein OS=Brevibacterium sp. HMSC08F02 GN=HMPREF3172_05360 PE=4 SV=1 +-----------------------------------THGDEGWSAWRALAVIDQSERTTVGLLGQLYGCSQPAATKIAARLTADGFITRRPDPDDARASLLEITDKGRQWLVSERTSAVQKMGSTVDDLTAEDVAALTRS------------- +>tr|A0A1C5YF95|A0A1C5YF95_9FIRM Uncharacterized HTH-type transcriptional regulator yusO OS=uncultured Roseburia sp. GN=yusO_1 PE=4 SV=1 +--------------------------HYLNHFMNLQKYDLTKNQWKALIIIANSSTLSMSQLAQRMNISREQASRTIAPLADRKLVERKINAENRRQIDISLSKEGRQLFNDLKSSTSNLICRSMDKLSEEEISEFKEA------------- +>tr|A0A1C5V069|A0A1C5V069_9FIRM Transcriptional repressor MprA OS=uncultured Blautia sp. GN=SAMEA3545264_02319 PE=4 SV=1 +--------------------------KVILNTVDFKDHGFTKTQLCILLSLTAKSPLTMSELAAYIASSKEQATRAVAPLVKAGYLERIQDEKNRKLVLVQLTLYGKEMMQIEEVKLKETMAAKINNLSPEDREAFAQA------------- +>tr|A0A1A0MHV1|A0A1A0MHV1_9MYCO Uncharacterized protein OS=Mycobacterium mucogenicum GN=A5642_25030 PE=4 SV=1 +--------------------------------LERVNISEAKLDVLMIFAAQLGQSedewtvrQTPSGIAEYFGITKASATGLIDWLENRKLVTRTRHATDRRSTPVRITPEGEKLVAEALPVFEQACGGLIDVLSERDRRDLQRILDKLWIHVK---- +>tr|A0A1F9WY92|A0A1F9WY92_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RIFOXYA2_FULL_39_19 GN=A2252_11185 PE=4 SV=1 +-----------------------------------DDQELTFIQRNILHYLRRNPNKTPSDVAENFCIKKSSITRIIDLLEKNGYVVSINDKVDKRRTFLNLTKKAQDKVKNIDNVPLQKLGKMFSVLSSKEQKVLLKGCA----------- +>tr|T0R237|T0R237_9DELT MarR family protein OS=Bacteriovorax sp. BSW11_IV GN=M899_2441 PE=4 SV=1 +-----------------LNRTTITLRTVLQNFFNKRDIDLTPEQWAIMGLvWNFQDELKSKTLSEHFFRDKSTVSRNLKKLEDKELIQFNPSLEDSREKIIKATTKSKSIQKKVYKTINDVLEIAEEGISDKDLEITLKTLAKMDDNLS---- +>tr|G2FMS4|G2FMS4_9FIRM MarR family protein OS=Desulfosporosinus sp. OT GN=DOT_0999 PE=4 SV=1 +---------------------------------EWSDLTF--KQFVYLDTILKMNKPTYSEIAKKFNITKPSVTAMVNKLIGLGYLERVQSVDDRRVYHISVGAKGRIMLAIEHNSVTGFAQQITSSLTEAEATTYIALTKKINAQY----- +>tr|A0A0A2TB26|A0A0A2TB26_9BACI Uncharacterized protein OS=Pontibacillus yanchengensis Y32 GN=N782_20340 PE=4 SV=1 +---------------------------------KEYGISP--TLESLLMVIIRLEHPTTTQLAEEMDISKSAVSQMITKLEDGDFVQKVVDPEDKRVQHLELGPKGKYYAQDLKRYEDYVHSLFAKSLNETEVDQVSQSFEKILQVM----- +>tr|K1Y578|K1Y578_9ZZZZ Uncharacterized protein OS=groundwater metagenome GN=ACD_77C00064G0001 PE=4 SV=1 +---------------------------------NFSNLTH--TQMHYLETISLLSNPNITELASYMELSKPTVKVAIDKLIEKELIFKIRSDEDRRSAHIHLAEKGKLINQMHDYAHKRIAEEFGNKLNKDEIEQLINILSKVLKDK----- +>tr|A0A1B8WPL3|A0A1B8WPL3_9BACI MarR family transcriptional regulator OS=Bacillus sp. FJAT-27264 GN=A8L34_03155 PE=4 SV=1 +-----------------------IMDRVVKDMSEKTG--LSeEGDFGILVRLVDLGNgvLRQQELVDSMEWTKSRLSHHLTRMEQRGLVLRKPLD-TGNGVQVIITDSGKSAVDASRPIYAKAVRkYFLDQLSDQDTELITKLAERTDKMAS---- +>tr|A0A1S2I0G5|A0A1S2I0G5_9MICO Uncharacterized protein OS=Curtobacterium sp. MCBA15_012 GN=BIV00_12970 PE=4 SV=1 +-----------------------VRQRVAEDIKAGSG--LSDQEFGILTRLVELGNgeLRQNELGALLRWDRTRLSHQLTRMENRGHVGREAV---DGGVLVRVTDAGAALVRAARPIHAEAVRkHLLHRVQGVDDATLLRTLEALAVDPG---- +>tr|E3J3N6|E3J3N6_FRASU Transcriptional regulator, MarR family OS=Frankia sp. (strain EuI1c) GN=FraEuI1c_1306 PE=4 SV=1 +-----------------LLRLAALSRQHCADQLSSV--GISQHQHGILCCLQEYGPACQRDIAARLSIDSGDLVAFVDGLQKDELITRQRDERDRRRQILSLTPAGARMLRHIEDLLDASEPGPLEVLPEDQRQEFLAAATLVLA------- +>tr|A0A1Q4ZCY8|A0A1Q4ZCY8_9ACTN MarR family transcriptional regulator OS=Micromonospora sp. CB01531 GN=A6A27_38470 PE=4 SV=1 +-----------------ISQTAVHARRLVSEAFAVS--SARGYHYRVLAALQEFGPASQAELGRRGRMDRSDVVAAVTELAREGFVERSADPADRRRNTVTITTAGIQQLQRLDRALDTAQDELLAPLSVAERRALVALLGKVLE------- +>tr|A0A0J1FLI3|A0A0J1FLI3_9FIRM Acetyltransferase YpeA OS=Desulfosporosinus acididurans GN=ypeA_1 PE=4 SV=1 +------------------------------------EFSLAEV--RVLYDIEHMEVCTAKKLIEELKIDPGYLSRIIKRFENDSLIYRVQSPEDGRLYYLFLTDKGKNTLSKLNDLSNDQIYNLISRLPERDKMSVVESMKTVENAFS---- +>tr|A0A1J1E523|A0A1J1E523_LYSEN MarR family transcriptional regulator OS=Lysobacter enzymogenes GN=LEN_1856 PE=4 SV=1 +------------------------------------PYTLTQA--RVLFELAQREPVAAREIGETLGLDAGYLSRIVQAFVDAGLVEKQRSEHDARSFALRLTGSGRAAFAVLDRRSHETTAAMLATLSPLDRERLLRAIAEAERALT---- +>tr|A0A222PAK9|A0A222PAK9_9FUSO Uncharacterized protein OS=Leptotrichia sp. oral taxon 498 GN=BCB68_08025 PE=4 SV=1 +------------------------------------NFSLNEY--RILNEINNLRDCTSKKICRNLYLESNFVNRTLRKFQKFNLVKKKLSLLDKRLYYFDLTKEGKNKLKNFNRMSDKKTKEIFSNLDIYDRERLVKDMSSIKMILD---- +>tr|B9JJ28|B9JJ28_AGRRK Transcriptional regulator protein OS=Agrobacterium radiobacter (strain K84 / ATCC BAA-868) GN=Arad_8715 PE=4 SV=1 +--------------------------------IREAGIPLDRALFPLLVLIERLGPIGVVDLADRVGRDHTTVSRQVAKLESLDLVVRQASAVDRRVREAIIAPKGKIMTDAVDGARDRIGDAILESWDVNDIDDLVRLMRKFADALN---- +>tr|A0A0R1SJL8|A0A0R1SJL8_9LACO Transcriptional regulator OS=Lactobacillus versmoldensis DSM 14857 = KCTC 3814 GN=FC27_GL000428 PE=4 SV=1 +--------------------------------IRIAGVDLEATSLQAFITIGRMQPTNVSDLANILGKSHSSVSRQIDKLESKEIVETENDHSDSRVRSIRLSCKGNQIIESINAARLEALKSAFSTWEEKDKQSLLSDLKHLSKTVD---- +>tr|C1CUV9|C1CUV9_DEIDV Putative transcriptional regulator, MarR family OS=Deinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923) GN=Deide_10800 P +-------------------------------------T--SLTRCQILTTVGRDGTLTLAGLSRRLNLDKGWLSRTIDDLVHSGLIHKQPSTTDKRTIDLTLTPQGQHRVAALSSELNDQSGRVIDRLPVTERHNVLRALELLA-------- +>tr|A0A0R1RXW1|A0A0R1RXW1_9LACO Uncharacterized protein OS=Lactobacillus fuchuensis DSM 14340 = JCM 11249 GN=FC69_GL001780 PE=4 SV=1 +---------------------------NIFRFINTESSDLTPLNSLIVCTVACHPGIAMSDLADQLGIAKSQLSRNVLTLEKLDLVERRHNTDNRRLVNVYANPAGNAMAQAQVLKVAQHLNGLLDKLEAPEQQRLDVLLSE---------- +>tr|A0A0R2I894|A0A0R2I894_9LACO Uncharacterized protein OS=Pediococcus inopinatus GN=IV83_GL000855 PE=4 SV=1 +---------------------------AISQNRFPDKFGLTRLQAITLRNVYRQSGITMTQLAQKIGITRPQLTRIIDTLEERGLVSRHHNDDNHRVINVLRTEKGKKVVKKHMDLIQSRIQRLVDTLDDEDQKALVTHLQG---------- +>tr|J6HFU2|J6HFU2_9FIRM Transcriptional regulator, MarR family OS=Peptostreptococcaceae bacterium OBRC8 GN=HMPREF1143_0393 PE=4 SV=1 +------------------VRLIKILNISIEKRVNndFKKMNLTMQQIKILLYLKERekNTveittqKDIQNLLGVTH---PTTISIIKSLEQKKFITSKHSEIDRRLKTLHLTENAYEMTQSIVKGKINFDNDLLRGIEKNELNACIKCLNKMYENINK--- +>tr|A0A173URV0|A0A173URV0_9FIRM Transcriptional regulator SlyA OS=Roseburia intestinalis GN=ERS852572_02280 PE=4 SV=1 +------------------GLRFSILDREFKRKLEerANRMGLTAVQLRVLGELSRAesMGaceinqKDLEKALAVTH---PTMTEIIKRLEKKKAVICTQSKVDARYKKINCADEYKNIHIELKKMDWEIFNKICAGIPEEDIQTFLKASEKMLENIEK--- +>tr|Q28Q22|Q28Q22_JANSC Transcriptional regulator, MarR family OS=Jannaschia sp. (strain CCS1) GN=Jann_2273 PE=4 SV=1 +----------------------------------LTPLKLDLYSSRIIVALAERGPLKVGQLVDLMALPQSTMSHQLKRMEKDGYVQRTRSDTDNRTVVITLTDEGETVSETCNRWSDQVLNSVSEELSDSEIEALSALLQRVFKSLPQ--- +>tr|A0A1M3MMY8|A0A1M3MMY8_9RHIZ Uncharacterized protein OS=Rhizobiales bacterium 63-22 GN=BGP07_01240 PE=4 SV=1 +----------------------------------FREDGLSIPAARTMVSLLEAGgEAPVGSVSEATSIDLSTTSHILRRLEKQGYVKRERDPEDNRVVIAFLTIEGKVVAKRCRQASLDHEAILTKSMAPADVATFKRLLVEAFDNAKD--- +>tr|A0A0Q9KC00|A0A0Q9KC00_9MICO Uncharacterized protein OS=Janibacter sp. Soil728 GN=ASG73_00735 PE=4 SV=1 +----------------------------SAMWSRVIGPQLTGPQFAVLDVLDAYDGSDQASVGHAAALDASTMVDVARRLERRSLIVRTRSPIDARRKVVQITSLGESELFRVRERRVQLEQRLFAHNPR-RKDEILAELNDL--------- +>tr|A0A0M2LL26|A0A0M2LL26_9MICO Uncharacterized protein OS=Leucobacter sp. Ag1 GN=XM48_16020 PE=4 SV=1 +----------------------------TASWGRAVSAEVTSTQFGVLTFLERFPGESQKDIGAHLSMDKSNMTDVANRLTRRGYVRVLKDPRDQRRNVLVLTPEGRSLLAELRPRVDALRADTFAEFSGGELLEFLGGMDRL--------- +>tr|A0A0L8EWG8|A0A0L8EWG8_9CLOT MarR family transcriptional regulator OS=Clostridium sp. DMHC 10 GN=AGR56_17360 PE=4 SV=1 +--------------------------------------GFTTTQCYTLLEISKFGSLSMNEISEKMNLNSSTMTRILDKLVRDEYISRSKDDNDKRIVIVSLREKGIEAASKLSDSVKAYYKKIIENIPEGQVEEILKSVNILQKAFEKAN- +>tr|A0A0Q4EH42|A0A0Q4EH42_9FLAO MarR family transcriptional regulator OS=Chryseobacterium sp. Leaf201 GN=ASE55_02240 PE=4 SV=1 +--------------------------------------DSTAVQALTLLKIDPKEGTRSTNLGPKMAIEPTSLTRIIKLLEDNGYIYKEKTTTDKREVIIKLTDKGLNSRNMSKEVVVNFNKRIMEKIAPEKLETFKEVMTEIMKIAVDLN- +>tr|Q97LD5|Q97LD5_CLOAB Transcriptional regulator, MarR/EmrR family OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VK +--------------------------------------EISVVQVHAIFEIGKLREVSTNEFSKILYLDKNTVNKIVNNLVDEKFVLRHIHPENTRHVILKLTENGQKIYENIRDDFKLYCKRILDNLPEKSRESITKDFEILLKSMEDNA- +>tr|F9DXA6|F9DXA6_9BACL MarR family transcriptional regulator OS=Sporosarcina newyorkensis 2681 GN=HMPREF9372_3437 PE=4 SV=1 +-----------------LRTVSGSLTQLYNRLLKPSGLKI--TQYYMLGNIFCFPNISISKLGELMLLDQTTVTRNLNILKESAYVTIMRDEYDSRTKIVSITETGIEKLNEAEPILSHVQNIVEESFGKKEYSDLVNKLEGLQK------- +>tr|A0A1D7UU03|A0A1D7UU03_9LEPT MarR family transcriptional regulator OS=Leptospira alstonii GN=A0128_03520 PE=4 SV=1 +-----------------LKRASRAIAQYFDHVLDPVGLTS--ARFNILMTLGTTEGMELAPMADLLVLDRTTLLRNLEPLETLGYIKDIPSE-NKRARKVALTEKGWDALRLAYPVWKVAHDHVVQNLGVPEWKSIIKGLRTISK------- +>tr|A0A231P5P3|A0A231P5P3_9DELT Uncharacterized protein OS=Desulfovibrio sp. MES5 GN=BCS36_04935 PE=4 SV=1 +-----------------VRKADRLLSQMYGRYFAKSGMRG--TQFALLRAIAAMPEPFITEIGRILGMDQTTVTRNVEKLEKAGLVETGPNPGDTRKKMVRLSASGKASLAVAEPCWAEAQQALLDGLGEDEARELLRLLAKVSA------- +>tr|A0A0N7M3F6|A0A0N7M3F6_9RHOB Homoprotocatechuate degradation operon regulator, HpaR OS=Phaeobacter sp. CECT 5382 GN=PH5382_02713 PE=4 SV=1 +------------------------------ARLKKHG--VQIEAWRVMELLDGDARLTMGELAKAALINPPTLSKLVDRMVSDGLVHRQIADEDHRQINLLLTDLGRLRMLQIREDVVQQDLQLRDQMAQEDSKQLLELLSR---------- +>tr|V6F114|V6F114_9PROT Putative Multiple antibiotic resistance protein marR OS=Magnetospirillum gryphiswaldense MSR-1 v2 GN=MGMSRv2__0761 PE=4 SV=1 +------ISPLTAHLGYWLRLV---SNHVSHAFAgKLEGRGVTVAEWVLLREVHDHRSISPSRLADRLSLTRGAVSKLADRLIDKGLLGREPSPEDGRAHSLALTADGRTLVPELAGLADSNDAEFFGDLTPDDRATMERVLKSVV-------- +>tr|A0A160PF47|A0A160PF47_9RHIZ TrmB family transcriptional regulator OS=Methylobacterium populi GN=MPPM_3194 PE=4 SV=1 +------SAEPVDPLRVWFRfiRL---SRRVTAAVAgELREIGLSIPQFDVLSTLSEREGLTQQELAARLYVTKGNVSGLIDRLVEAGLVERRAIPGDRRSHALHLTGAGSEIAARGIAAQAAYVARTLGRLDEADLRAFEELVVKWR-------- +>tr|A0A0W0YCV6|A0A0W0YCV6_9GAMM Transcriptional regulator, MarR family OS=Legionella santicrucis GN=Lsan_3442 PE=4 SV=1 +------VSPLKSHIGYHMRVV---SNEVSQAFAkKLSKYDVAVAEWVILREMYETKkSTSPSAVAEMVGLTRGAVSKLIERLLNKDLVTRTESSNDRRFQQIKLTSKAIQLVPSLADSADQNDESFFGVLSDNEKGTLIKILKKLS-------- +>tr|A0A1J0A647|A0A1J0A647_9ENTE Uncharacterized protein OS=Vagococcus teuberi GN=BHY08_05810 PE=4 SV=1 +-------------------------------------LNITYEGYYCLLGLTQVPSMTMTDIATDFYFGKQQTTRIISQLVSHGLVEKTVSPLDKRITNVSISEKGMSYLKRNPFDTTDLGEDLNEKLTKEEMEELNHALDVLLKI------ +>tr|U2CT75|U2CT75_9CLOT Transcriptional regulator, MarR family OS=Clostridium sp. KLE 1755 GN=HMPREF1548_02192 PE=4 SV=1 +-------------ILIGLHRVSNEIDRRTTRIVKCYG--LSMGQFAVLEALFHKGDLTIGQVQEKILSTSGTIPVIIKNLEKRGLLIRLPDAGDKRKCILHITEQGSSLIQQVYPENEAMIIESMHNWTNDEKCELLKLLKKFGGGT----- +>tr|A0A1X7MVH9|A0A1X7MVH9_9LACT Transcriptional regulator, MarR family OS=Carnobacterium iners GN=SAMN04488700_0815 PE=4 SV=1 +-------------LMVVFGKMARTLQENLSKNLEELG--MPFSLYPILAYLNEVEKAKTQKLGEVAVISSGTITHTVNKLLKLNYVEKIQDEQDKRVFWIQITKEGKKRFMEVHLKHMEYLDELLKEFSEEDKTALIELMKLFGKGI----- +>tr|A0A0D2W283|A0A0D2W283_9PROT MarR family transcriptional regulator OS=Skermanella aerolata KACC 11604 GN=N826_39745 PE=4 SV=1 +---------------------------------------------------GANPGLRPSVLAHFILKDRSAMGKLLEQMERTGLLEQKVSVTERRARELYLTPKGRALAQQVREVARRQSDDFFSVLTDEEQDALMRILRKVYESY----- +>tr|A4AV27|A4AV27_MARSH Probable transcriptional regulator OS=Maribacter sp. (strain HTCC2170 / KCCM 42371) GN=FB2170_00245 PE=4 SV=1 +------------------------ADGYMRNCLKEFG--ITENQMTILFALSKLGKVEQGKIGEALVLERSTVSRNVKLLQKYKLVRRTT----AYRPEIELTNEGIDLVNKLIPHWEEVMDSLVDMMGDYGTVPLEKLEQRL--------- +>tr|A0A246FXK2|A0A246FXK2_9PSED MarR family transcriptional regulator OS=Pseudomonas sp. K2I15 GN=CEC48_18065 PE=4 SV=1 +------------------------MAQIYDEAFVPFG--LKATQYSLLNHIANGDAPKMRDLAQSLVMDLSALGHTLKPLVRDGLVVLQVDELDRRSRRVLLTDAGQRKFEEARVVSKQMAVRFDEVFGAEAACELRRSMDFI--------- +>tr|D9Y1E8|D9Y1E8_9ACTN MarR family transcriptional regulator OS=Streptomyces griseoflavus Tu4000 GN=SSRG_02836 PE=4 SV=1 +-----------------------------ALLTERHQITFSA--FEVFCRLRESEePQAMRSLARLlVSVSPTRASRIVQEHIDAGHLARAADQTDGRISLISFTDAGRRYADAASRTFEQAIDQHFAGvLDEEDMNALLRIWEKLRQT------ +>tr|A0A0T1Q6P2|A0A0T1Q6P2_9ACTN MarR family transcriptional regulator OS=Streptomyces sp. Root431 GN=ASC82_13110 PE=4 SV=1 +-----------------------------SDVQRDGRIPLTW--YDVLLELRGAGeqGLRMQEVAERVVLSRTRVSRLVDEMARSGLVTKQPDSTDKRVTWAVITDEGRSALRATAPAYMRGIREHFGRyLTDEEATVITTALLRVAHS------ +>tr|A0A0P6RB12|A0A0P6RB12_9RHOB MarR family transcriptional regulator OS=Phaeobacter sp. 11ANDIMAR09 GN=AN476_09850 PE=4 SV=1 +-----------------------------GEFSAVHGISVNE--FLLLLHIKRSAsnRLSRVDLAKRMHVSASTITRMAAPMEKVGLVGREVDQRDARLIFVVATDAGQEKLSEALATFSKRASYLFSDrWEVDEVDQFASMLGRLIGG------ +>tr|A0A1V2NVG4|A0A1V2NVG4_9ACTN MarR family transcriptional regulator OS=Kribbella sp. ALI-6-A GN=BWI15_31785 PE=4 SV=1 +-----------------------------RHSLKRSGLQMAM--FELLLRLARSHgeKQRLTSLARELTVTTGGITRLVDRAENLGLVRREPCPDDARGSFAVLTEEGKRRLREALPDHLLEIDSLWTSqLADERELVLG-RLRRVRDN------ +>tr|A0A1Y5SNJ1|A0A1Y5SNJ1_9RHOB MarR family protein OS=Tropicibacter litoreus R37 GN=TRL7639_02239 PE=4 SV=1 +-----------------------------RALVMAGLPKLNW--YDVLWELEQHPdGLRPVRLEERLLFDQSSFSRQVMRMAEEGLLTREPAADDKRGKVLRITAKGRDMRARMWVIYRPHIDAGMQSaIEAGGLEDVEAASRKR--------- +>tr|A0A1I6S5X6|A0A1I6S5X6_9BACL DNA-binding transcriptional regulator, MarR family OS=Marininema halotolerans GN=SAMN05444972_106167 PE=4 SV=1 +-----MTHDTIQA-FQHVVHKLRrGIQQQLEE-------NWGVADFVFLHQLHTQGPSKGSDLSSELNVTNSHVTQHVNRMVKKGWISRHRSTDDKRIVELAITPAGTEVYNEMVKRRFQYFQQLFHTLSDEELDSLLHLLQKLID------- +>tr|A0A1G6SYK6|A0A1G6SYK6_9BACI DNA-binding transcriptional regulator, MarR family OS=Bacillus aryabhattai B8W22 GN=SAMN04487777_10380 PE=4 SV=1 +-----LIQDVVST-MRNQTKKMQmSVIPTLKS-------YIPLNEFLALHMLYKEGNHIVSEIAEHMHISNSSMTCISDRLMEREFVTRVRSQKDRRVVYLSITDKGKAFAEEMEKVLTKEYGEKLSHFTDEELQTFLRLLNKMDI------- +>tr|U1N2M3|U1N2M3_9BACL MarR family transcriptional regulator OS=Exiguobacterium chiriqhucha RW-2 GN=M467_06175 PE=4 SV=1 +-----LVADAERG-IRMNYRGVKkNLRSMFSQ-------YLTRNEFFILRSLCQNSPQIASALSNEFQFSASMITALADELTKKGLISRERSERDRRVVELQATEEGRALFETLEDMKIEYLMDVFTDFSDDELILLSRLLDRMDA------- +>tr|A0A136WCM8|A0A136WCM8_9FIRM Transcriptional repressor MprA OS=[Clostridium] neopropionicum GN=mprA_3 PE=4 SV=1 +--------------------------------------DLTLRQLMLLIAithLNPQE-TTIVNIASALGTSKQNINRLVNYMVKSGYLSRKYGQIDKRNVNIEITNKGLSVMQKNTINSNKYFLELFKNFSKKEIKALHQTLKKLA-------- +>tr|A0A178KTE0|A0A178KTE0_ACHLA Uncharacterized protein OS=Acholeplasma laidlawii GN=A2I99_02320 PE=4 SV=1 +-----------------------------------ELESLSMQQAAIVKYLIHHKDKdlNSKDLEQAFSMRGSTCSRMLKAMEQNDMVVRIDDKEDSRKKIIKPTEKSIQIIRNIKSKFDEMENRIKDNISKEELEVFFRVIDQIKQNIT---- +>tr|A0A1F1GJZ0|A0A1F1GJZ0_9CORY Uncharacterized protein OS=Corynebacterium sp. HMSC078H07 GN=HMPREF2875_07455 PE=4 SV=1 +----------------------------------LDELGITYQQYLMLMILWDSeEPVTLESMEKRLQPESGTFEGLVKGLEESGLATVEDG-------KVIITQKGSDLEPRAVCIPETILNEYrKSGVDLVEF---RESLEIVREAG----- +>tr|U7V807|U7V807_9FUSO Transcriptional regulator, MarR family OS=Cetobacterium somerae ATCC BAA-474 GN=HMPREF0202_02397 PE=4 SV=1 +---------------------------------NLKIFNLESSQGIILLKIKELKKITPTQLVDLGVIEKPAISKTLKKLEGLGYIIKSQSNQDARSFYVSLTKDGERIASHVEEFLDKLDKKFHTILTDDNIQEIKNVLDYLE-------- +>tr|A8TJ10|A8TJ10_9PROT Uncharacterized protein OS=alpha proteobacterium BAL199 GN=BAL199_16243 PE=4 SV=1 +-------------------------------------YEIdlTHRAIRVLQFISHHEkAPGLDEITKFLGSAPSTASELIKRLQNKGLVVRRRSSQDERTIEIELTGSGRAALTEHTSLNPRKLQNGLQALGDLEQEYLIGFIKKVTEAI----- +>tr|D1Y2T5|D1Y2T5_9BACT Transcriptional regulator, MarR family OS=Pyramidobacter piscolens W5455 GN=HMPREF7215_2172 PE=4 SV=1 +-------------------------------------GRLSAPQLRTICVIGRNEDIRMKDIADRMELTTGTVTVMIDRLQVMGLVERCRNENDRRSYKILLSERGRAYYEEHRKRQKELVRKLALKISDSDREVCERVLENFMHCI----- +>tr|A0A1V5HLA8|A0A1V5HLA8_9BACT DNA-binding transcriptional repressor MarR OS=Tenericutes bacterium ADurb.BinA124 GN=BWY97_01184 PE=4 SV=1 +-------------------------------------RGIklSMKEVHILETVRNTPVPTMSAVARKLRITTGTLTASIDRLVRKKYVRRGQEEKDRRKVIIELTEPAFAVLKIHDEFHNEMIEAIFADMKIDEDEILLKSLENISNYF----- +>tr|A0A196NK31|A0A196NK31_9RHOB Uncharacterized protein OS=Sulfitobacter sp. EhC04 GN=A8B82_04975 PE=4 SV=1 +------------------------------DFRARLGDeALHPGYFTILTLIVRNPHISQTQIGTASARDKSSVTKALRWMEDEGLIVRLRSASDRRIHLSVATEKGIRQQALMEAKAIGHLQSLNDAIGSERYATFIATLKDLIR------- +>tr|A0A1F6TE13|A0A1F6TE13_9PROT Uncharacterized protein OS=Candidatus Muproteobacteria bacterium RBG_16_65_31 GN=A2V92_00925 PE=4 SV=1 +------------------------------DLARLPSDaGMTPGEFSLVTVLGANPGIDSVTLARVYRLDKATLSLTLKRLTQRGLIWSERRSEDRRYVALQLTPAGRGALRRATRRIEKQERIMDSVLEAGEKERLLELLGRISR------- +>tr|A0A0Q8QXF3|A0A0Q8QXF3_9SPHN Uncharacterized protein OS=Sphingomonas sp. Root710 GN=ASE00_07330 PE=4 SV=1 +------------------------------LFLEVSSdIDVTPVQYAALQAIRDNPDNDQRLIGGLIAVDRTTINVVSLRLEQKGWIVRHVIG--GRRLHLELTQAGRQVLIDMAKVIPAHAERILAPLEPAQRDSFMAMLKTlveQNNDLSRA-- +>tr|A0A0Q4B0P1|A0A0Q4B0P1_9EURY Uncharacterized protein OS=Methanomassiliicoccales archaeon RumEn M2 GN=AOA81_05385 PE=4 SV=1 +----------------DQHIAPRVIKQYLDSRMTarLESLGLQGSQGPYLLAIARNPGASLKEIAAHLMVDKSITTRTVGTLIDMGLVRNESA--DARRYSLVLTGEGDNAVERIEETFSEIWDALLCDLTEEEQRAFESACAKIKAR------ +>tr|A0A1S2JDM2|A0A1S2JDM2_9MICO MarR family transcriptional regulator OS=Curtobacterium sp. MMLR14_014 GN=BIV02_01250 PE=4 SV=1 +----------------ALGHAVKRAQYRNHRTMDaaLRDLGVTLVQWDALRAIDRMPRASGHDLAVATFQSDQAFGTLANRMLDRGLITRTAG--RGRRIEHAITEDGRRVLDEGHRIAEGVLDSLFAPLDEQRRAALLQLLTTLTDA------ +>tr|A0A1Q4W828|A0A1Q4W828_9ACTN Uncharacterized protein OS=Streptomyces sp. CB02923 GN=A6A06_37520 PE=4 SV=1 +----------------EIGALSRIIRHHFADRIEqvIHPLGLTLGQWTVLRELKRTPGASASELARAAVHTPQAVSRLVRTLQEEGLVERSPA--RGRMMDNHLTAKGHKVMDETFLQIEARLAPVLEKFGRADTEEFRRLSHLLIEA------ +>tr|A0A1A0JHH3|A0A1A0JHH3_9MICC MarR family transcriptional regulator OS=Kocuria sp. ICS0012 GN=A5728_08670 PE=4 SV=1 +----------------------------------HRE--LSMVHTNILSYLACVPGRRAKDIVAESGLGASGMSRHLSALEHLGYVTRTRDLEDGRAQIVEITAEGRKALEANLRADAETLVARLGDLGEDEAERTRVDLNRLTELFLT--- +>tr|A0A0G8B2J0|A0A0G8B2J0_SERMA Uncharacterized protein OS=Serratia marcescens GN=AAY84_23835 PE=4 SV=1 +----------------------------------NHG--LTLSKARVLKAIEEHEACNATDVMTVLSYSCRSVTEALESLEAAGLITRHKAPGNRKVKIITLTGQGKERLHLAMQIRNDILTALLSCLEGSELVLFSDIINKIWLNHGK--- +>tr|A0A1Q6WWH2|A0A1Q6WWH2_9BACT Uncharacterized protein OS=Gemmatimonadetes bacterium 13_2_20CM_69_8 GN=AUH12_04105 PE=4 SV=1 +----------------------------------LGPKHLSLSHMRALGFLDATPDAHLSAVAGYVGLALPSTSSLVDGLARRGLVVRLATpPHDRRRLRLRLTGAGKGALRTGLAAARAALDARFGGLSPGERALIARAMARLRPLLT---- +>tr|U2KYH7|U2KYH7_9FIRM Uncharacterized protein OS=Peptostreptococcaceae bacterium oral taxon 113 str. W5053 GN=HMPREF1987_01486 PE=4 SV=1 +---------------------------------------------------KYPEGLTSAMLSKISDKDKSDVSRSLNAMMKSNLVEKHSVHQKGYAGIFLLTDEGKKVAYEIIKKVNFAVKMANENLSEEKRVVFYEVLEIFIDNMTKIV- +>tr|A0A0Q8PBT4|A0A0Q8PBT4_9BURK Uncharacterized protein OS=Noviherbaspirillum sp. Root189 GN=ASE07_08640 PE=4 SV=1 +-------------------------------------EGINLPEWLVIYTIALYPDIGPSRIGHFTGLHKTTISRVLSQLRDKGYIEQCVDPNDGRGKILSLTSAGKKIFVRRSGWAREWSTLLTSGLSAADRRALARMLDVVIDNSR---- +>tr|A0A0Q5ZEK0|A0A0Q5ZEK0_9BURK Uncharacterized protein OS=Ramlibacter sp. Leaf400 GN=ASG30_04995 PE=4 SV=1 +-------------------------------------LGLTSRQWRVLVILNRLGTSPSGEVARMANFDHSQVSRVAFELAEKGLITQASDPVDRRKQILALTPAAVECLRDGVPVSLEREARLRSRLSPADYDTFIRALGALEEEAQ---- +>tr|S6GNN7|S6GNN7_9GAMM Putative OhrR transcriptional regulator, MarR/EmrR family protein OS=Osedax symbiont Rs2 GN=OFPI_30650 PE=4 SV=1 +----------------------------------LEALNLTYPQYVVMMALWEEDGITVQVLLEKTAVNGGAMSLILKKMIDKKLLTVTPSEEDKRKKLIHLLPTGQQLQDQAAEVPT-KIQCSFPNIEKADLHQLIGLLDKVCLDLADN-- +>tr|A0A178NDY2|A0A178NDY2_STALE Uncharacterized protein OS=Staphylococcus lentus GN=AXY34_11690 PE=4 SV=1 +------------------------FHYLCKDVAQSHGISLKLA--NLLEIIYEQDGITLNNLCRKVDEDKGNLSRLVNDLMKDSYVIKKQSERDKRIYYIYITEYGKEAILNLKQVCIHNMDSLLSILSEEEQNHFIKALTKLDNHVY---- +>tr|A0A1M6G1X7|A0A1M6G1X7_DESDE DNA-binding transcriptional regulator, MarR family OS=Desulfovibrio desulfuricans GN=SAMN05660830_01444 PE=4 SV=1 +-------------------------------QLSVHGINFTE--FMILQSLENAAENTMRriELANAVNLTASGVTRVLHPMERIHLIEKRSNPRDARISLVKLTSAGKTIYADALITVESCAESLMAPLTSNQIETLTGLIKKLS-------- +>tr|W9DPV6|W9DPV6_METTI Transcriptional regulator OS=Methanolobus tindarius DSM 2278 GN=MettiDRAFT_0779 PE=4 SV=1 +---------------------------------------FNTLPNKTIRLIHFKKEINPSRLGIILGVGKSTITSTIDTLEKNGLVVRNNDPDDMRKQLISLTDAGEDYHFELMDMITERVSSISDsyGMSESDlveyydhLSQMVSILNKYIFET----- +>tr|T0D2B4|T0D2B4_ALIAG Uncharacterized protein OS=Alicyclobacillus acidoterrestris (strain ATCC 49025 / DSM 3922 / CIP 106132 / NCIMB 13137 / GD3B) GN +--------------------------------------LPSCNQLLVLKELDEVERMRLTDLSAALKLSPSTITGICDVLEQKGYIRRDRDLIDRRIVYVSLTAHGRTCLRSTRDSMIARLGSVAHTFK---egdLETAVAVLNAINRSL----- +>tr|A0A1Q9HD89|A0A1Q9HD89_9VIBR MarR family transcriptional regulator OS=Vibrio ponticus GN=BIY21_03305 PE=4 SV=1 +-------------------------------------------EFDYLKVIQQYpQGVRITDLAQELCVSKPSASNMVTRLAKKNLVGTIACSEDARAKRVVLTDWVIENMSFERVVYQQIATDLNAQLSKQEAKQLVQLLNKALKK------ +>tr|A0A1N6RQR1|A0A1N6RQR1_9RHIZ Transcriptional regulator, MarR family OS=Rhizobium sp. RU33A GN=SAMN05880561_102688 PE=4 SV=1 +-------------------------------------------ELDYLYLVIAAeKPLRLADLADQMRVSRASASVMVRKLHLAGYLDKLSDSADGRSVLLAPTAKCSALIAEEKSIYAETADRISRALTPDELEDLDRLLKKARGS------ +>tr|A0A1R4B8Q9|A0A1R4B8Q9_9VIBR Uncharacterized protein OS=Vibrio palustris GN=VPAL9027_03350 PE=4 SV=1 +-------------------------------------------DYRYLDAVLIAdCACSVDYLATQVEGDIQSTQADIDTLCEKHYLI------MSELGRVSITELGKQKLANDRRVHALMALEMTASMSDEEAHLLDSVLHRS--------- +>tr|R7MQH0|R7MQH0_9FIRM Transcriptional regulator MarR family OS=Ruminococcus sp. CAG:624 GN=BN739_00205 PE=4 SV=1 +--------------------------------------ELHFGQFAVMNYIYDHDGCTQADLAENLKVTPASIATSTKRLQKAEMITKRIDEDNLRCKHLSVTDKGKAEIVQSRRLFDDYDSRLFSDFTDEELSVFNQCLIRLIIKMSE--- +>tr|A0A0Q8DMP9|A0A0Q8DMP9_9ACTN MarR family transcriptional regulator OS=Nocardioides sp. Root614 GN=ASD81_15585 PE=4 SV=1 +----DVVRELESEVGVLIRRIRRVI----GERARAVHPELLPASYLMLAYVRDHEPIRASAMCAVFDIDKGAISRQVQHLIDLGLVDKQPDPEDGRATLLSISTEGEQRLEAVAVERRELLAERLADWSADELTAFSGSLRRYND------- +>tr|A0A0D8FSY4|A0A0D8FSY4_9ACTN MarR family protein OS=Ferrimicrobium acidiphilum DSM 19497 GN=FEAC_18720 PE=4 SV=1 +----AFLKEIEdgiRSMIRWSRRHSSLL----A---HDLYQGLDLTALTILSALADHPGSRLTNIAEWLKLDLSNASRQTSLLESAQLIERTTDPNDRRSTLLSLSPEGRKVLDKARSDSTNFMHRIYQDWETVELAQFASMITRTID------- +>tr|A0A0Q5BYA2|A0A0Q5BYA2_9MICO Uncharacterized protein OS=Rathayibacter sp. Leaf299 GN=ASF48_03720 PE=4 SV=1 +----RALAEVEEQITALAVQVRSAV----RDAAAAIDPSLPPFGLRLLRMLERCGPVHASVAAERLGVDRSAISRQVRQLAELDMVEMTVDPDDGRARFLALTALGRERMAHLGGEQRQRMHRALRTWPEEDLLAFAGYLERLTT------- +>tr|A0A101KYI7|A0A101KYI7_9MICC Uncharacterized protein OS=Arthrobacter sp. EpRS66 GN=AQ436_05840 PE=4 SV=1 +----DRYSLAEQELFSLIAVTARFK----RELAHRLNGQLTPGYLPVLGLILRNGRITQSEICEKLLVDKATLSRMISKLEQLDLVVREVNAEDRRASDLLPTDYAKERWHSGFEQWRKELRSRMSNWADDDLDTLVELLGRLNL------- +>tr|A0A126Z964|A0A126Z964_9MICO Uncharacterized protein OS=Frondihabitans sp. PAMC 28766 GN=AX769_19940 PE=4 SV=1 +------MEAVYMQMETISRRAVARN----R----RTSAPLTVVQHTLLTFIASTRDCRAIDIAAALRLNRSTISRQVGDLVELGLVAAGASDAharehedagsggPGRGQILALSARGSELLQRSLEANHHELARRLADWTDADIDVLASGLERFNA------- +>tr|A0A1F1U9J1|A0A1F1U9J1_9MICC Uncharacterized protein OS=Arthrobacter sp. HMSC08H08 GN=HMPREF3175_07580 PE=4 SV=1 +----EQLRSLTREYRILLAAARRSF----REQAAALDASLQPFDGVVASALYRRfmetgsctpdAGMTVTELSEVVDADKSMVSRAIKRLETAELLVRTADPKDARSYLLVLSDSARARFKDYVMKRQQESAVMFEDWSIEEVSRLAALLKKLND------- +>tr|A0A1R4JWE6|A0A1R4JWE6_9MICO Transcriptional regulator, MarR family OS=Mycetocola reblochoni REB411 GN=FM119_10000 PE=4 SV=1 +----EQITALESALLGIVTEAKRTI----HARAERIAPDMQRGTFTLFTQIARLEPISAGSLAELLSLDRSVVSRSAKTLVEAGLIERHPNPSDGRGAVFSASARGRAMLDEARSAESARLRTEMGNWSAADVTRLTELLSRLAA------- +>tr|A0A1Q3Q9G9|A0A1Q3Q9G9_9ACTN Uncharacterized protein OS=Actinobacteria bacterium 69-20 GN=BGO26_02395 PE=4 SV=1 +----PPDVRGRRPLSSVLRH---AE----MLFVAEFEERIAASdfadlslahAANVLRFLYR-GPQRASQFIGSCGVSKQAVSLQIAQLEKRGYITSAPDPQDQRARILALTERGEAAEAE----VQRIFVAIEKTWTkhlgAEDAKALRRILEKLP-------- +>tr|A0A1S7S450|A0A1S7S450_9RHIZ Transcriptional regulator, MarR family OS=Agrobacterium genomosp. 7 str. Zutra 3/1 GN=AGR7C_pAt0189 PE=4 SV=1 +----RHLKELGHELNALLAASRAIT----SASAERFHPQIQPAAYQIAMVLSMLGAARGSQLSQLLETDKSAISRLLKSLCDFGLAEPVTDPDDRRSTIYRLTQEGQSRVEASIEVKIGAFYSRTEGWSDAELSQLTELLRKFNR------- +>tr|A0A1Y3LXM2|A0A1Y3LXM2_9MICC Uncharacterized protein OS=Arthrobacter agilis GN=B8W74_06590 PE=4 SV=1 +----TVLGALEESAAAMCRNEQRVC----WTLARGVSAAMEPGAYSVLAAARRLGPCRVTDLAVTLGMSASAISGHVAALAGLGFVGRVEAVEDERSRRVTLTDDGRRRVDGARTGRRTYFRAQLRGWPTVEIVELADLLARFNE------- +>tr|A0A081JIB7|A0A081JIB7_STRMC MarR family transcriptional regulator OS=Streptococcus macedonicus GN=FD61_04085 PE=4 SV=1 +----------------------------------LKPYNITIMQSWVLMFLKRTENcYTFKELEKQFEVSQPTMAGILARLDQKNMIITSKDEKDKRIKKVEISDEGRSLINRLGEHLDDSERAIVGDFSKDEQEMFHLLLERAYYNVV---- +>tr|G5KD27|G5KD27_9STRE B-block binding subunit of TFIIIC OS=Streptococcus urinalis 2285-97 GN=STRUR_0546 PE=4 SV=1 +----------------------------------LKHYDLTPSQFKILRYVNHFKEKKirQIDIEHTFNMSNPTVTGILQNLEKKEYIKRLPNPEDKRSKVIILSQKLKDQKLNFERISQEINNTFTKNLDSEQSQLLADLLHELLDGRQK--- +>tr|A0A1F8NBQ8|A0A1F8NBQ8_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_13_60_13 GN=A2Y61_05555 PE=4 SV=1 +-------------------------------------ADLSGVEASLLAFVKESKGPVtPSVLARQLHREPHTVSGLVSRMEKRGLVKKEKNLGRRNLVRVTLTKKGEEAFKKQGKVSVPST-IMLTAVTDKERAALTDYLGKL----HR--- +>tr|A0A1E5TYB7|A0A1E5TYB7_STAXY Transcriptional regulator OS=Staphylococcus xylosus GN=AST15_09025 PE=4 SV=1 +-------------------ITSKEVANRFNKY--LKQYDISFPNYIVLLYIENEVPVYIKTLCDELYLDSGTISPIIKRLEKKDLIRRLRTEDDERRVKVMLTTKGIK---LKEEFSKISEDVIQqFDMEKEDSLAYYQILKTFAERNIY--- +>tr|A0A0R1LUH5|A0A0R1LUH5_9LACO Uncharacterized protein OS=Lactobacillus acidifarinae DSM 19394 GN=FD25_GL002366 PE=4 SV=1 +-------------------------------------GEITAHQIMALSYINQHPGAIQQDLVTLTQRRAPTVSVMLKRFERDNLIVRkIPSD-NNRNKEITLTEHGQEIVRSFQQATTATDELAIADFTPTQTAQLIALLTQMNQH------ +>tr|A5N087|A5N087_CLOK5 Predicted regulatory protein OS=Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680) GN=CKL_2521 PE=4 SV=1 +-------------------------------------SELTLAQAHILSYLKRNGIVAFNELVIQLGIDKASLSRILNNLAVKDFIKIEKSHTDKRMKYISMLPLGMKAIINGDYESNKFINQILHFGYEDGNNGIAKAFKE---------- +>tr|Q30VN1|Q30VN1_DESAG GCN5-related N-acetyltransferase OS=Desulfovibrio alaskensis (strain G20) GN=Dde_3472 PE=4 SV=1 +-----------------LARELRLVGSYAD------QKGLTVAEAYVLIELGEHGTLSVQQVAQLLLIDAADASRAVQSLILQKLAVLVPEGPPDRAKGVALTEAGHRRLAEVHGEMDSLVRAGLDQLTPGEQKAVADGLMTYARGLRY--- +>tr|A0A0W0YLB8|A0A0W0YLB8_9GAMM Putative transcriptional regulator, MarR family OS=Legionella shakespearei DSM 23087 GN=Lsha_2756 PE=4 SV=1 +-----------------IVQELGFLDNQFS------NIG-SFSECHALYELKQSKRLTATQIGKLLKLEKSTVSRLIKSLQDKGYCLVEPDPRDIRSKLVKLSENGEKAAQHIDRVANQQVAVALELLSSEEKKQVMNGLYLYAKALKQ--- +>tr|A0A1I5T9C8|A0A1I5T9C8_9GAMM Putative acetyltransferase OS=Enterovibrio norvegicus DSM 15893 GN=SAMN03084138_03139 PE=4 SV=1 +-----------------LLRHRGLLDNIYG------TSGLTTIQCHVLIELEQKN-LNADQLASRLNIDVANANRTLAILINNNNIAYHVK-SAHTQPSYQLTDTGRTRLNAHHEGINQEIALYLEQLDSDEIDVLSSSLSRYNRAMEQ--- +>tr|A0A241W3I7|A0A241W3I7_9GAMM MarR family transcriptional regulator OS=Acinetobacter sp. ANC 4558 GN=B9T31_01245 PE=4 SV=1 +-----------------LVRELGMLSRKTI------GTELSPLQSHILIELNQTEQgLGVTELANILCVEKSSISRTLKTLEKSELLSRKINPTDARSVTFSLTEKGESRLIEINQYANQFTAEALMLSSEVELQQLRSTVKNFTKALKN--- +>tr|F6DR47|F6DR47_DESRL Regulatory protein MarR OS=Desulfotomaculum ruminis (strain ATCC 23193 / DSM 2154 / NCIB 8452 / DL) GN=Desru_1501 PE=4 SV=1 +------------------------------QFKELLHENITPAQFMLLKLICHKAECKAADIAQILEVSPAAATNMLERLYKNGWIERGRSEKDRRVVWLKLTPSGKELLTDVEARRIDLMLERFKNVTEEEMVFIKKIFLNV--------- +>tr|A0A0M3T477|A0A0M3T477_9MICC Transcriptional regulator OS=Arthrobacter sp. ERGS1:01 GN=AL755_10210 PE=4 SV=1 +-------------LMRWVGWAqMKAGE----DWIR--ERELSHPQSFVLGYLVQNPGAIQRDIAKVTRTTAASVSSLLQGLETRGLVERRTEAGNERSKRVYATPAGVELISGFDTAMAGTEESILTPLDTDERTALHALLAKITAELPQ--- +>tr|A0A1M3EJX2|A0A1M3EJX2_9CELL Uncharacterized protein OS=Cellulomonas sp. 73-145 GN=BGO38_16760 PE=4 SV=1 +-------------LIGRISSRlRQAMGDA-FDSAD--LGGLTPLQARTVGFIEAseGRGLIQKDIADVTGTRPATVSALLGTLERDGWIERRTDPSDARRKTLHVTPKARDMVKRFEAGVWASGERQLDVLDADERRTLVALLTKLDQHLSS--- +>tr|A0A175RZ09|A0A175RZ09_9MICO Transcriptional regulator OS=Curtobacterium luteum GN=NS184_04965 PE=4 SV=1 +-----------------------------------DLPDIPDAQIEVLRRLDVDGWSSPTALGRALGLARSTVSNLVAAMERDGLVERRLARGDGRSTEVGLTELAQRRLAVYDESAERVLVEAMAAASAADRRVLADvgdVLARLRQRLEG--- +>tr|A0A1A5I6V6|A0A1A5I6V6_RHILI Transcriptional regulator OS=Rhizobium loti GN=BAE38_31515 PE=4 SV=1 +----------------------------------LEPVGLRITQFLTLAALSEVECVAVNALAERLDIERTAMGKMVGFLERDGFVAIEASPTDGRSRLIRLTEAGHHLHEKAAPLWQEAQKQFEELNGANSTSEMRQRLSDM--------- +>tr|E8V390|E8V390_TERSS Regulatory protein MarR OS=Terriglobus saanensis (strain ATCC BAA-1853 / DSM 23119 / SP1PR4) GN=AciPR4_1635 PE=4 SV=1 +----------------------------------ISPAGVNITQLAVLRCIARRVGEPLVRVAEEMEMDRTSLYRAIAPMIRDGWLTSEDA-STSRFRTAEITAKGRKLLTVANKRWERVQRNIIGKFGQREYGKLLAELDRL--------- +>tr|A0A1C0NVT2|A0A1C0NVT2_CITFR Uncharacterized protein OS=Citrobacter freundii GN=AN688_0225785 PE=4 SV=1 +----------------------------------LDAYGINIAQYSLMRLVINNNPVSLTRLGDIAGLDRSTVGRNVTVLARQGWLQVDRDGMDKRQQQVSITPEGEALIRDAFPSWQRCQHIIEERLGADNVMALQNIFHQI--------- +>tr|A0A0Q9P663|A0A0Q9P663_9GAMM Uncharacterized protein OS=Rhodanobacter sp. Soil772 GN=ASG75_10935 PE=4 SV=1 +----------------------------------LAGDDLSVVQWLLMSELARGEGCTLTHFVRATSRDAGSLSRAIHQLSQRGLLDNRRSHFDRRSSTISFTAAGRAMHERLAPDIEQLTQTINLGADAADLDRI---------------- +>tr|A0A0F7HP14|A0A0F7HP14_9STAP Uncharacterized protein OS=Salinicoccus halodurans GN=AAT16_11975 PE=4 SV=1 +-------------------------------------------QLIVLNELQTFGRMTQNELAEKMVISKGAVSQIIKNLENKELVTREVEETDRRNRFLVIEEKGLETISRAEKHAEALREEYMDLIPEEELTNYLNTQRKFTDYLKS--- +>tr|A0A1E5TWT9|A0A1E5TWT9_STAXY MarR family transcriptional regulator OS=Staphylococcus xylosus GN=AST15_12190 PE=4 SV=1 +-------------------------------------------QILALSKLKEEGPQKTSSLALSLGYTSGAITKLTNNLIKEDYIVREQQENDRRVILITITDRGLDVLEEAQKQGRNMRNEVYSVLNTQEVEQLLSIQKKLFERVKY--- +>tr|A0A231VR61|A0A231VR61_9MICC MarR family transcriptional regulator OS=Rothia sp. Olga GN=B9K03_10160 PE=4 SV=1 +---------------------------------------LSYVEYMVLAMLSESPELslTMTELALTTNTLPARLSRVVARLEKDSLVERSISREDRRVSICHLLPAGLERIQQVAPGhVAEVRRQIFDHLNEQQVYDLANIGTSVLGDTPSKLI +>tr|A0A1Q8INF1|A0A1Q8INF1_9BURK MarR family transcriptional regulator OS=Burkholderia sp. SRS-W-2-2016 GN=BTH42_28885 PE=4 SV=1 +-------------LTYVIGSLDRILRRRMSEALAPLG--LTLAQFTALSVLDANGRASNAQVAERSFITPQSANEVMNAMSARNWVSREPDPTHGRIVLLQLTDEGRAVLRECEQAVKAIEKQMLDDIGVDTAAGVQQHLEAFVRNLR---- +>tr|A0A1Q6TSJ1|A0A1Q6TSJ1_9GAMM Uncharacterized protein OS=Acinetobacter sp. CAG:196_36_41 GN=BHW62_05185 PE=4 SV=1 +---KQDIL-LEQKIGLRLSRIGLLSKIFAGQQFVKNCFDITPEQFTVLYTLKINNGMYLRQLASVTLKDRPNITRIVSILEAKEYLTSAIDKEKRMVKKLYITEKGLDVCEKVLPSILNIWQDTVANISEEEIEKFLETLNKIEVNL----- +>tr|C6J183|C6J183_9BACL Transcriptional regulator, MarR family OS=Paenibacillus sp. oral taxon 786 str. D14 GN=POTG_02160 PE=4 SV=1 +---------------------------------------------------------------------SGAITQIVERMENKGLVRRFQLMRGSNKVNVILTDKGESVYFAYEEFFVKPFdQWIRDELNENELKSFEKGVKKLIEFLNE--- +>tr|A0A1W9TAL8|A0A1W9TAL8_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium 4572_123 GN=B6I22_06340 PE=4 SV=1 +---------------------------------------------------------------------KGGVSQNLKRLETKGLSFKEIDPENLSRSIVKLTTKGLTAYWAHKHWHESMDgGFlkYLEALKPGEIETIIQFMERVEDFLKR--- +>tr|A0A0C2E838|A0A0C2E838_9STAP Uncharacterized protein OS=Salinicoccus roseus GN=SN16_02000 PE=4 SV=1 +---------------------------------------LSREQLYIIEMVAEEPGITQKTLIGRLKREQTSISRAVQKLVDQNYLIKRQHHDDMRASYLEVTEQSRETLEELEEKICEVTDDVLEKLDRDEKKALTDILEKI--------- +>tr|A0A101VE46|A0A101VE46_9SPHN Uncharacterized protein OS=Sphingomonadales bacterium BRH_c3 GN=APF78_00605 PE=4 SV=1 +------------------------------DYALLAEGEITTAQAAALMIIGQRAPVSQREVARILEQNESAMTAMVRRLMALGYVERQRAADDVRRWDLLITTAGANALKQAGQAFGQVNRAIEARLSPHEIA----ELARLLNLLS---- +>tr|W4BAV9|W4BAV9_9BACL MarR family transcriptional regulator OS=Paenibacillus sp. FSL R5-808 GN=C169_07188 PE=4 SV=1 +----------------------------------LSKESITGSQAEVLRVLEERGPLSLKELGFLLICEGGSPSRLVNTLVQEGYIIRDTHPKDSRAVILRLSDKGVEKSKRVTLVEQELYTMISRKIDKDKLESINQILCEL--------- +>tr|A0A1Y5SE52|A0A1Y5SE52_9RHOB Transcriptional regulator SlyA OS=Pseudooctadecabacter jejudonensis GN=PSJ8397_01899 PE=4 SV=1 +---------------------------------------LSITEWRVLWDLVEAGPLTVTEMATIQRTDHALISRTIPPMIEKGYVVTTTGAEDRRTSLVAITPSGHTVFDETSATMAQRRTAIKDAFTEAELDTFLALIDRFE-------- +>tr|R7AGR8|R7AGR8_9CLOT Uncharacterized protein OS=Clostridium sp. CAG:43 GN=BN653_01749 PE=4 SV=1 +---------------------------------PSHDMKVNSLPFFALIALDSW-ADQDYTMSELADKlsiTKQQLSHMIKVLEERGLVERIHDTANRRRVYIRICDSGREMMNQMKQEMLSSTLFGLRAYTPEELASMDECLCRLM-------- +>tr|W6S022|W6S022_9CLOT Uncharacterized protein OS=Clostridium bornimense GN=CM240_3139 PE=4 SV=1 +---------------------------------EVGKVKVNSHSFNILLSLNRQ-KDKMLSMSKISNYlqtTKQQLSKLLNDLEDNGYIERIRYKTDRRNVYVKLTEYGMKYLFNLKEAFAEKLDCEISKYSNDDIDILSDVIIKLN-------- +>tr|R5WH04|R5WH04_9DELT Uncharacterized protein OS=Corallococcus sp. CAG:1435 GN=BN495_00318 PE=4 SV=1 +---------------------------------NLVSIKDIPISMTQLTCLNIINRQSQLTMSDLADElnmSNQQLTKVVDALEGFEMVERTYDPKNRRKIYAKVTQKGKDTLQKLKQELDRKLGKIMLEVSDDELDKLYECIAHIA-------- +>tr|W1UG16|W1UG16_9FIRM Uncharacterized protein OS=Intestinibacter bartlettii DORA_8_9 GN=Q606_CBAC00380G0006 PE=4 SV=1 +---------------------------------KISNFGVTYTQLFVLIYIGKNNGCSPKEIVEYLKIDAGQLNRILTKLLEKDLINQRKNNNDRRFNVLSLTESGKNIVQESQKLFYSWDTQVLSDIDENSIQELMNLMKKIIFKLNE--- +>tr|T3DAM3|T3DAM3_CLODI MarR family protein OS=Clostridioides difficile CD160 GN=QEW_3451 PE=4 SV=1 +---------------------------------CLKPYKLTNGLYFYLIYINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGEEVLGDIKNIFSKWDNSIKKEFSDEEYKELVKKLHIVKDIKTT--- +>tr|A0A1Y3RVA0|A0A1Y3RVA0_9FIRM Uncharacterized protein OS=Gemmiger sp. An87 GN=B5G38_08450 PE=4 SV=1 +---------------------------------RLKELGLSQGLLYFLLYVGRHPGCSAGELASVIGADSGHTTRSVEKLVQQGFMTRTRSQQDKRAVVLELTEQGREAFVQAGRWFYQWEAQRTQGMSPEEVTQLKGLLQKAMTGIPM--- +>tr|G9Z7X1|G9Z7X1_9ENTR Multiple antibiotic resistance protein MarR OS=Yokenella regensburgei ATCC 43003 GN=HMPREF0880_03533 PE=4 SV=1 +VKTTSDLFNEVIPLGRLIYMVNQKKDRLLNDYL--SPLDITATQFKVLCSIRCATCITPVELKKVLSVDLGALTRMLDRLLCKGWIERLPNPNDKRGVLVQLTPEGAAICEQCHQRVGQdLHQELTKNLMADEVAKLELLLKKI--------- +>tr|I2B8D4|I2B8D4_SHIBC DNA-binding transcriptional repressor OS=Shimwellia blattae (strain ATCC 29907 / DSM 4481 / JCM 1650 / NBRC 105725 / CDC 9005-7 +MKHTRDLFNEMIPLGRLIVLVNQKKDRLLSEHL--SSLDITASQFRVLCAVQCEESVSPRELSKILSVDLGALTRMLTRLACKGWLERLPNPADKRGVLLRLTPQGNAMCETCRNLVGPdLHQELTKNLTAQEVATLEYLMKKV--------- +>tr|A0A1R4I958|A0A1R4I958_9VIBR Transcriptional regulator, MarR family OS=Vibrio sp. JB196 GN=FM109_00570 PE=4 SV=1 +LGTDKeKQRLSYEEIILRIHRLSDHLAADVQHYL--EPYNLQQADFSILISLYRQGTpyiSSPTQLYQTMLFSSGGLTKVLKRVEDFALIHRIDNLKDKRSKLVQLTPLGLQHIENILDKIKQSRHQRFSCLEIQEQKEMELLLTKL--------- +>tr|Q2IZE3|Q2IZE3_RHOP2 Transcriptional regulator, MarR family OS=Rhodopseudomonas palustris (strain HaA2) GN=RPB_1709 PE=4 SV=1 +---------------------------------LLRAHGLSEQQWRILRALTEVEAIEVTELADRAFLLGPSLSRMLRDLEARKWIARKPAKDDQRRSRVSITPKGLKLIETVAPFSEQIYADIARHFGDAKLAALQDMLGALEADLT---- +>tr|A4X7E9|A4X7E9_SALTO Regulatory protein, MarR OS=Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) GN=Strop_2351 PE=4 SV=1 +-------------------RVMVVVQTGTARDL--AVLGLSEPDYEVLSTLSERPGHtsTLGEQADKMGWSRSRLSRHATRMAARGLLKRTPDPNDGRGCFLVLTAQGLDALKDAAPAhVESVRRHFIDRLAPEDLVAIEQIAQKLKEPQAGDDR +>tr|U7KG88|U7KG88_9CORY Uncharacterized protein OS=Corynebacterium sp. KPL1986 GN=HMPREF1287_01657 PE=4 SV=1 +-------------------AMQRALHKELANALQ-AAANVSEADYAVLAVLQRRRGQstRPHELAAELGWEKSRLHRQLVRMEGRKLVTRRHAEElGPRAIEVTVTKIGEGAFAAALGShTAKVEEKVVSVLTEEELRQLGSISRKITRHLAGGA- +>tr|A0A1F1YB51|A0A1F1YB51_9CORY Transcriptional regulator OS=Corynebacterium sp. HMSC14B06 GN=HMPREF3130_03825 PE=4 SV=1 +-------------------NAKRAVDRSIDLQLQ-DSLDISTADFSVLVVLSEAEDNvvRMRTLCESLEWDRSRMSHQITRMERRGLVTKERCACDNRGIDVTLTEHGRTVIEKAAPNhVKLVRHVLFDVLGENiDYQGISAVLDKIAATANAAVT +>tr|A0A0K2H370|A0A0K2H370_9CORY Uncharacterized protein OS=Corynebacterium lactis RW2-5 GN=CLAC_04455 PE=4 SV=1 +------------------------------------RTGLTFADFTLLIALHETEDGImhVDQVCDRLKWNHPRALLHTNRLVKRGLVHTEEPGEDPDsDYVIVLTGVGRHVFVEATPDyVDTVRTEVIGQLSEEDRVNMMKCFHAVL-------- +>tr|A0A1Q2HYQ8|A0A1Q2HYQ8_9CORY HTH-type transcriptional regulator MhqR OS=Corynebacterium glaucum GN=mhqR1 PE=4 SV=1 +------------------------------------SHGLGLTDFRALTLLSEAPDHElrITELSTQVGLNQSSTTRLVARLETKGLVVRDTCPDDGRGIYAVITEAGLNLVHTLAVPyVERLQTLVASTITNDPATS--RAFSTILN------- +>tr|A0A1V9BMA0|A0A1V9BMA0_9BACI Transcriptional regulator OS=Geobacillus thermocatenulatus GN=B1692_16355 PE=4 SV=1 +--------------------------------------DLTQKQ-VMLLELLRHQTMTINEIAESFSMTPSAASQLVRKMEEKAYVRRDINPADRREIIVRLGQAGQAYHKKMDEVELHLMEKYYGKLRREDLEKLKEINDKLYDLI----- +>tr|A0A0A3YIF9|A0A0A3YIF9_9ENTR Uncharacterized protein OS=Erwinia typographi GN=NG99_25650 PE=4 SV=1 +------------------------------------DENISTSLFTLMEVVSLSPGIDIRTAAQMASIEESNAVRIVMRMVRTRIMSDPRDPNDARRSLLSLTGNGQAIFEQLQARLPLVQRGLTQKLPPVAVEEFHRLTRLV--------- +>tr|A0A222TJK0|A0A222TJK0_GORRU Transcriptional regulator HosA OS=Gordonia rubripertincta GN=hosA PE=4 SV=1 +-------------------------------------PDVTGPQYAVLWAIAERKVATHTEIATLASLDSSTTLDIVRRLTARGWIVPVADVVDKRSRPVRLAEPAITALRFIEPAVSGVQAKLIEPLTETAQTQFIDNLRLV--------- +>tr|A0A1I2T958|A0A1I2T958_BACME DNA-binding transcriptional regulator, MarR family OS=Bacillus megaterium GN=SAMN04487776_102881 PE=4 SV=1 +---------------------------------LLQHYGITPFQYHILLIVERARTMPVTKVADEIKASPSVITASITRLHELNLVERYHSKRDRRKVMVELTNKGKQVIQAAEKDMQQEVEKLFACYKEEEQQQFLTLCRQLDEHV----- +>tr|A0A1M6B6E2|A0A1M6B6E2_9CLOT Transcriptional regulator, MarR family OS=Lutispora thermophila DSM 19022 GN=SAMN02745176_00293 PE=4 SV=1 +---------------------------------------LNKSQQKALFIIQKKGRVMPSSLGKAMDMQKGSLTTLIDSLVEYGFVRREADCEDRRKQWIILTSQGEEYISKLMSCFEKEFERIFEKVDSQDIYKLLESIEFA--------- +>tr|R7LZM5|R7LZM5_9FIRM Uncharacterized protein OS=Acidaminococcus sp. CAG:542 GN=BN701_01713 PE=4 SV=1 +------------------------------------GVPLTMIESHTLTYIDDHPGTTVTELTHFWHKTKGAISQIVTRLEQNGLVSKQKKADNAKLVRLYTTEAGARASNAHKMYdiidITKTLGEIGEKCTPEEIDTFFRVMQVYYGVISK--- +>tr|A0A1P8XC27|A0A1P8XC27_9MYCO MarR family transcriptional regulator OS=Mycobacterium sp. MS1601 GN=BVC93_17210 PE=4 SV=1 +----------------------------------LKPLGIGMPEYVCMSQLAGRPAESNAELARRTGVSPQAMNNVVKSLQELGALTRPDSVSTGRSLPVRLTPKGRRLLVRAEAVVRKASEQILTPLSAEERVTLERLLRSLDLNAV---- +>tr|R5D6P1|R5D6P1_9FIRM Uncharacterized protein OS=Dorea sp. CAG:105 GN=BN457_00869 PE=4 SV=1 +-------------------------------------------------------GLTAAGLCELCKEDKAGISRILNDLENRNFIAYEATgAAHRYRSRAHLTDVGIACAREMRSFISHALEEASKDIAEPQRKIFYKTLFTIADNLEHLSK +>tr|E7MKM3|E7MKM3_9FIRM Uncharacterized protein OS=Solobacterium moorei F0204 GN=HMPREF9430_00068 PE=4 SV=1 +-------------------------------------------------------GLTNTELVECSKMDKAAVSRSLADLAKGKFIRFEYRnGKSRYGAHAVLTTTGKEVTEHIVERIGKVLTKALGHLSSEEKKFFVANMATVASAMLEIVE +>tr|A0A1E5U6G7|A0A1E5U6G7_9STAP MarR family transcriptional regulator OS=Staphylococcus succinus GN=AST12_08470 PE=4 SV=1 +-------------------KSYCLMKDKYDSLLQKYDLTEAKFSIMMLLTYEKDMTLAPSDLAEKLGSKKSTITGIIKGMEKRNLIRRKVLPNDKRTNYVQLTNEGSELLKRFLPFNYDLVSKVFEVFSEEEKEQFYMLSNKLKNHLEK--- +>tr|A0A0J8WYV9|A0A0J8WYV9_9MYCO Uncharacterized protein OS=Mycobacterium conceptionense GN=ACT17_12050 PE=4 SV=1 +------------------------------------TGELTLTQCSVLYHLTEIRRARVIDLAAREHVTTATMAKAVRRLQELGMVRRQRDLSDYRSSWIEITTKGVQTQQAAVAG---LREAMVNELSAEEISALQTAL------------ +>tr|A0A0P1IQQ2|A0A0P1IQQ2_9RHOB Transcriptional repressor MprA OS=Thalassobius sp. CECT 5114 GN=TA5114_01741 PE=4 SV=1 +---------------------------------------ITVAEWRILVNLAYSNSKTVRDIQQRVHLDKAKVSRAVVGLEDRGYLTKKIDPDDRRLLHLELTEEGETLVAELVPLAQEFQSKVAEKFQDdfaTLQSQMTQLMKALSDG------ +>tr|A0A0M6ZM82|A0A0M6ZM82_9RHOB CRISPR locus-related DNA-binding protein OS=Labrenzia alba GN=LA5096_00173 PE=4 SV=1 +-----------------ARRTANLLTRHYNRHMAALGLELT--QAQLLAVIADGTAPSASAIARYLGIDRSTLARNLRPLEAAGLIRRR-E-TKGRTVLPILTPAGEQKVVEIHQRWLAAQAELSAMLGPEGADAVRSHMSALRK------- +>tr|I5BAC1|I5BAC1_9SPHN Regulatory protein MarR OS=Sphingobium indicum B90A GN=SIDU_15594 PE=4 SV=1 +-----------------LRAANRAVMKHYVDSMAGSPVNPV--QMSLLMRVYYLRNATMQTLAQHMETDRTTTTRNVDVLVRDGFLEIGEG-KDRRQRLVRLTERGHEALEVSIPKWRKAQDELKNALGDELWNNILREARTLIE------- +>tr|G0AAQ4|G0AAQ4_COLFT Transcriptional regulator, MarR family OS=Collimonas fungivorans (strain Ter331) GN=CFU_3524 PE=4 SV=1 +-----------------LRQLTRKMTNIYDHYLAADELTIS--QYSLLARIGKYGPIGVIPLAHNMGMDRSTMSRTLKPLIGAGWIETVDlpleMLTDKRSFGVRLSAEGERKWKQSKPNWRKAQDVINTILGDQTHHALMSLVDDANV------- +>tr|A0A160TER8|A0A160TER8_9ZZZZ Transcriptional regulator, MarR family OS=hydrothermal vent metagenome GN=MGWOODY_Tha2183 PE=4 SV=1 +-----------------LRKADRVINHVYNRHLAECGLSVS--QFSVMRAMHYAGTCTSQVIQDILVLDQTTLSRNLKKLVSDGMVVMKEDKGDRRRKLLSLSAKGKIMFSAGEKQWKLAQNEMRETLGNSIADQIIELSDAIVG------- +>tr|S5P7U0|S5P7U0_9PROT Transcriptional regulator OS=Arcobacter butzleri 7h1h GN=A7H1H_0190 PE=4 SV=1 +-----------------MRQISRKITNIYDEFLKPSNLNVT--QYSLLSNLKRVQPIKMNDFSKVVKLDRTTLVRNLKPLINLSLIEIKSI-DKSKAQLLELSQKGIELQNEGYKYWQKAQEYIEQTINHEELEIFYTIVKKMES------- +>tr|A0A1B3ZIC0|A0A1B3ZIC0_9SPHN Uncharacterized protein OS=Sphingomonas panacis GN=AWL63_23670 PE=4 SV=1 +-----------------LRKASRAFARLGDQTLAPCGMTAV--QFTILRSIENRGPdgWPLSKLAETMLMERTTLYRALSPMKRAGWIEISNP-NAGRVKVVAATAGGRLAFERANALWAQAQARILTAFGTDRWRVLSGDLTDLTG------- +>tr|A0A1Y1STQ9|A0A1Y1STQ9_9RHOB Transcriptional regulator OS=Stappia sp. 22II-S9-Z10 GN=ATO13_11326 PE=4 SV=1 +-----------------LRRIARQITTIYDGALAENGVSIV--TYAVLSALSREEPLTLSALADRVGTDRTTLSRTVERMRQAELVAATPG-DDRRERRLSLTDHGRDTVAAARKSWRETETMLIERYGADRLATLHELLADLEA------- +>tr|A0A1N7BAC5|A0A1N7BAC5_9MICO MarR family transcriptional regulator, transcriptional regulator for hemolysin OS=Microbacterium sp. RURRCA19A GN=SAMN05880568_ +--------------------------------------DAPAAQWRTLKLLREHGPQRVGDLATLSRVSQPGMTRLVHQMESAGLVARGIHADDSRVSVVSATEEGLRELDRWLAALSAALAPHVADLTDAEWDAVRTsa--DALALRVGMQ-- +>tr|F6F269|F6F269_SPHCR Regulatory protein MarR OS=Sphingobium chlorophenolicum L-1 GN=Sphch_2937 PE=4 SV=1 +----------DEQLLTDLSRVITLMRRSFDRAMTEQGASLA--QTKLLTCIKAQSGtARAADIAEIMSIAPRTVTEALDGLEREGLIQRTPDKADRRVKRLTLTPAGEAAVAVTEPLRRELSAKMLAALNPSDRAHFHAALQKLLEAL----- +>tr|A0A1W9JGQ6|A0A1W9JGQ6_9PROT Uncharacterized protein OS=Proteobacteria bacterium ST_bin13 GN=BVN33_16600 PE=4 SV=1 +----------VDALLSGVIGLLRRFKLEPGLLADSvyADLHHN--DIGLLTHLQPGDGRPVRVLASEFGAPDSTISSALDRLARRGLIRRIPSETDRRSVLVSLSAEGEVLADRLLQIQRDNCRAMLAALPPGDRATLIRLAGVMVTDA----- +>tr|A0A1X9UMK1|A0A1X9UMK1_9SPHN MarR family transcriptional regulator OS=Sphingomonas sp. DC-6 GN=HY78_02760 PE=4 SV=1 +----------EEELITGLAKAYMLMHRRVNRAMTKQGASLA--RTKMLAYIRKAGGsARAADIADLFDLAPRTVTESLDSLERDQLIVRTSDPQDRRVKRLAITPLGESAIAATEPLRKELMAEICAVLSEDDRVQLHDILSRFVASL----- +>tr|W0EEP1|W0EEP1_9FIRM Transcriptional regulator OS=Desulfitobacterium metallireducens DSM 15288 GN=DESME_13870 PE=4 SV=1 +----------------------------------FSKTGISDSQFSVLLALEELGPLTMGELCKQIFTACSTATDLANRLERDELVERIKDDKDHRVVRMHLLPKGKKIVQDYIQERQHFLEAVLEESPSNEYIALLETLEGFAERMDISEN +>tr|A0A1F7BJ98|A0A1F7BJ98_9BACT Uncharacterized protein OS=Candidatus Peribacteria bacterium RIFCSPHIGHO2_01_FULL_55_13 GN=A2881_04300 PE=4 SV=1 +----------------------------------MRGMGVSMLQLHGLLTIREKPGMTMKELASHLAVTSPTATVFIGRLESQGLVERIHDTKNRKMVRVSLTAHGRELAEGAYRHFEDAFREVFGMLPKAELHTLIHIFTHLIRLHTEKTH +>tr|A0A0F4M017|A0A0F4M017_9LACO Putative transcriptional regulator, MarR family protein OS=Lactobacillus mellifer GN=JG30_00730 PE=4 SV=1 +-----------------------------------KQFGLTGVQVQIIDYLNHLpqNqFVYQKDIERAFNIRRSTATSVLQKMEENELIVRNVSPSDSRVKVISALPKAEELQPQISQFLESSNAQLLSCLSTLQRHSFLKALEKMPQELAR--- +>tr|W1UZV1|W1UZV1_9LACT Uncharacterized protein OS=Leuconostoc sp. DORA_2 GN=Q611_LSC00312G0004 PE=4 SV=1 +-----------------------------------QPHGLTAVQMTIIDYLSNASrVTTQHDIEQEFNIQGSTVTVMLDRMANKNLITRQKSTKDKRINEIHLTTRGFEVSDIIKGYIAEHDSRMLAPFTDAEQTVILQFLKMVGQSVTQ--- +>tr|A0A0M2U4K1|A0A0M2U4K1_9FIRM Uncharacterized protein OS=Clostridiales bacterium PH28_bin88 GN=SY88_10370 PE=4 SV=1 +----------------------------------LDKYGLPPASRAVMRQVHHNQGITVSEVSRRTGMVKSHVSKTVDSLVEQGFLEKRPDPSDQRLIRLYITEKAGEHFGQIQVEIRHRLSEVIAEFPEEKIEAITDGLRTLKAILEQG-- +>tr|A0A1T2A5G9|A0A1T2A5G9_9RHOB Uncharacterized protein OS=Thioclava sp. F28-4 GN=BMI87_05730 PE=4 SV=1 +----------------------------------LEPGPCTPIEISVMRFVGRNPGVSARAAADACRLPTSNFARVLKGLVAKGLLERRSDPQDARIAHLHPTELAEKNSLR----MREHWAAALSGVglERDKIAATTQALRRIEAHLSAA-- +>tr|R5LP39|R5LP39_9FIRM Bacterial regulatory protein MarR family OS=Eubacterium sp. CAG:115 GN=BN470_00516 PE=4 SV=1 +--------------------------------------------WILYFLRLNNGTCQQKELASSLSQPKQTTNSAVKQLERGGYVTLKCGS-DRRCRLVELTPKGSGLAVSTSDHVIAAERETWGDFTEEEQDSLIELLSKYNKRLKT--- +>tr|R5DZ77|R5DZ77_9FIRM Uncharacterized protein OS=Eubacterium sp. CAG:86 GN=BN798_00415 PE=4 SV=1 +--------------------------------------------WILYTICYYGEGVTQKTICEEWFYSAQTVNSSLKLLEKKNLIELRLAPGNKKNKQIFLTEEGKDMTNRLIVPVIEAEKLSFDAFDIQELKKMFRLSFEHVKQLEK--- +>tr|R6L8N9|R6L8N9_9FIRM Uncharacterized protein OS=Coprococcus sp. CAG:131 GN=BN485_00212 PE=4 SV=1 +--------------------------------------------WIIYILTIENkAELTQAELCDTWFIPRQTCNSAVKKLEGKGLISLTTHKGAGNIKYLSITENGVSFANKYITPLTNADISSFSSFTDEERELLLSLMQRQLDYLKK--- +>tr|A0A0E9F6J7|A0A0E9F6J7_CHLTH Transcriptional regulator Hpr OS=Chlamydia trachomatis GN=ERS095036_10918 PE=4 SV=1 +--------------------------------------------LVLSAIYDSKEECTQKKISQRWLVPKQTVNMILKDFEKQGLVELSPMRTDKRRKTICFTPKGKEYAKTILSKLRKVEMNAIDEMGIERMKRFNEDAALFVKLLGK--- +>tr|A0A1J8KNC2|A0A1J8KNC2_9FIRM Uncharacterized protein OS=Eisenbergiella tayi GN=BLA28_30880 PE=4 SV=1 +--------------------------------------------LVLLSLREGKEPCTQKQICEQWTLPKQTVHSILRNFLEREWVTFHVLENDKWNKGVSFTRSGSAFAGEVIDKLQSLECRVWERLGNEKSNALLESTILYVSYFRE--- +>tr|A0A1Y4IVB9|A0A1Y4IVB9_9FIRM Uncharacterized protein OS=Lachnoclostridium sp. An196 GN=B5F29_03465 PE=4 SV=1 +--------------------------------------------WSLLLIHDG--VETQSRISEQLFMSRQTLNSAFKQLVKKGLIVLEPYEDNQRTKRAVLTPSGDRLVEEQVTRMHRIEEQAWEKFSQEESEALARLTRKYTDVLGE--- +>tr|R7D4H5|R7D4H5_9ACTN Transcriptional regulator MarR family OS=Collinsella sp. CAG:289 GN=BN589_00478 PE=4 SV=1 +--------------------------------------NAVSGEMAVMRALMLANgELSPSQIADRAWVSAPRVANILRNLEAKDWVTREPDKADRRRVIVKITEHGLACIEEKRELSNRKTGEFLAELGPDDAHELVRLIHRMNEIIEKNQ- +>tr|R6W404|R6W404_9FIRM Uncharacterized protein OS=Ruminococcus sp. CAG:382 GN=BN636_00121 PE=4 SV=1 +--------------------------------------GFHKGGQFVLDYLANQKnGIsPQKNISRDMIVSSARITVLLKNLEEKGYIRRMKDPSDSRQELVSITESGRDAIGRLRDVLITRTAEVLEALGSHDAEEYFRIQKRIFELTYNTR- +>tr|A0A0R2AYE6|A0A0R2AYE6_9LACO Uncharacterized protein OS=Lactobacillus brantae DSM 23927 GN=FC34_GL001071 PE=4 SV=1 +--------------------------------------ENALGVDYVLFQYLDQHeNVTPSDLSQALHVTTARMTVILRRLEKANMITRSAHPTDLRKFIIALTPTGRKKLKDQETKQLTYLTDLMAYLGEEDAEAYIRIVSKLAKRRNQSK- +>tr|R6GWG8|R6GWG8_9FIRM Uncharacterized protein OS=Firmicutes bacterium CAG:137 GN=BN490_01067 PE=4 SV=1 +--------------------------------------MRAQGESLVLHLLARHPdGMVAEEIRQIMDVSSARVAAILANLERKDLIIRLIEPEDRRRLRIMLTPAGQTHAETEDAYIIDRLEQSLAVLDDEEIQCCIRVLHKLENLHHR--- +>tr|A0A1C5M544|A0A1C5M544_9CLOT Transcriptional repressor MprA OS=uncultured Clostridium sp. GN=SAMEA2393091_00524 PE=4 SV=1 +--------------------------------------SSMKGEAFLLMYLWKKQdTATPGELGKAMKTSSARVAAALNNLERKGMIARKAEEKDRRKIRVELTGKGEEQAKQWQKMPLCMVTRLMEQLGEEDAKQMLHILKRINEIMPQID- +>tr|A0A1C5Y4T5|A0A1C5Y4T5_9FIRM Homoprotocatechuate degradation operon regulator, HpaR OS=uncultured Ruminococcus sp. GN=SAMEA3545434_01456 PE=4 SV=1 +--------------------------------------ELFQGESKVIVYLSTAEgIVYPSDISRDLMISRQRVTSVLSAMEKKGFVSLVRDPEDKRRVQVKLLPKGEKSIEEKQQRLEKYFSVFVDALGEENLKNLLDSSEKAVEALEHTM- +>tr|A0A0M7ARZ9|A0A0M7ARZ9_9RHOB MarR family protein OS=Labrenzia alba GN=LA5096_05189 PE=4 SV=1 +---------------------------------------LNPSQFAALSYLARANrfSRAPSHVAEYLVTTRGTASQTLKALARKGLICESRSETDKRSIRYDVTDLGKDMMKAP-SGLANVIDDLPDEivnGLTGSLKTLVREILKTRK------- +>tr|A0A1F4G2Z7|A0A1F4G2Z7_9BURK Uncharacterized protein OS=Burkholderiales bacterium RIFCSPHIGHO2_01_FULL_63_240 GN=A2711_17215 PE=4 SV=1 +---------------------------------------MDIVHLRALLFLDRANrySNTLAGLTDYLGLTKGTVSKSVALLEQAGHLRRTPDSQDRRVQHLSLTASGEDVVQRLLThlRLGDIARCMGMPqaeQATQMLRHVLSTCQRLNQ------- +>tr|A0A127PXP7|A0A127PXP7_9BURK MarR family protein OS=Collimonas pratensis GN=CPter91_0127 PE=4 SV=1 +----------------------------------YQPFDLTAPQGFVLRTVLRRPGLLSSEVASVFGIARPTATRLLDALLAKQLIERRPSAEDGREWNIFPTAAGQALDKPINAVSAEVAQRLRAQVGSDRFDDSIAALRGVRESIG---- +>tr|X0PDY1|X0PDY1_9LACO Uncharacterized protein OS=Lactobacillus composti DSM 18527 = JCM 14202 GN=FC83_GL001073 PE=4 SV=1 +-------------------------------------------QGKILVLLAQEDNLPQKEIATRLNLTPQSTAEFVGKLARKHYVHKTKSQKDRRITLIQLTGQGRDALKNIDNTIPSYL----EFLDDDEQQQFGKLLAKMNLGL----- +>tr|A0A1F1DDX6|A0A1F1DDX6_9STRE Transcriptional regulator OS=Streptococcus sp. HMSC072C09 GN=HMPREF2893_09630 PE=4 SV=1 +------------------------------------GISLTRYQ--ILQYLLEQAPCNQIAVQERLQIDPAALTRHFKILEKEGFVHRSRNPKNQREIVIHLTDTAYNWLVNRPPRYHVaVKEQMSRILNAQEQEQFSYLLDKLV-------- +>tr|A0A0C2VSU3|A0A0C2VSU3_9BACL Uncharacterized protein OS=Jeotgalibacillus soli Cunha et al. 2012 GN=KP78_03620 PE=4 SV=1 +--------------------------------------DLTPVQYTALEFIILRESVSARALSDFLKVKPAAVSSLITRLEKKNFISRMEGKADRRMINLSATSEGQEVYDRIFHRFSTMLDQIYTKLSCDDHMHFERIIRKLNEETK---- +>tr|R4K176|R4K176_CLOPA Transcriptional regulator OS=Clostridium pasteurianum BC1 GN=Clopa_1958 PE=4 SV=1 +--------------------------------------NLQPQDMYILERIYFKKKLKVKDISKEYNIPASTTTGIIDRLEDKKYIKRTRDNVDRRIVELIATEEGCEVIQNHINQDKIFAENLFNTLEENKKIAFKQLLSELINKVN---- +>tr|A0A134ALI0|A0A134ALI0_9FIRM Transcriptional regulator, MarR family OS=Peptoniphilus coxii GN=HMPREF1863_00047 PE=4 SV=1 +MKAREFLWTYWNLLKEANDTKMSLMDYFSENY------GLTQLQLLVLGKIDSLDDTSIRSIARSLHRDHGNISKICTVLERKGYVYRERSVTDSRIVHVYLTEQGEKYIDEFSSIVAPLYDKLGDHLTDGDLRFLLKSMEIIESLFNQS-- +>tr|M3VEV6|M3VEV6_9ACTN Putative MarR family transcriptional regulator (Fragment) OS=Gordonia paraffinivorans NBRC 108238 GN=GP2_023_00010 PE=4 SV=1 +----------------------------------LKPFRVSKRGLLVMITLFvdPDSSKALGQLSKILMVHPTTVTLTIDQLESAGLVERRPHPTDRRTVLASLTETGQQTMKQIADSLAESDFGF-PAAAPDSAHALTVALHQV--------- +>tr|A0A0N0YQY5|A0A0N0YQY5_9ACTN MarR family transcriptional regulator (Fragment) OS=Streptomyces sp. NRRL F-6602 GN=ADL27_41755 PE=4 SV=1 +------------------------------------------------------------------MPVPKPLSLPFDPIARADEsWRERWGPVPAMAAITSIMRAHQ--------------I---------LLAEVDAVVKP---------- +>tr|A0A1H4KVA2|A0A1H4KVA2_9NOCA DNA-binding transcriptional regulator, MarR family OS=Rhodococcus koreensis GN=SAMN04490239_0928 PE=4 SV=1 +----------------------------------LQPHGLSYPRYELLNLVAgtADGTIDKVVLDHALDRHSTTTRTMLQGLECSGLVEWYRNPQDRRSTIVSITAAGRERIQRATRVLDNAMPSDRalFDCFTDTAHSLSLTLRDF--------- +>tr|A0A1Q7QGJ3|A0A1Q7QGJ3_9ACTN Uncharacterized protein OS=Actinobacteria bacterium 13_1_40CM_2_65_8 GN=AUI42_01225 PE=4 SV=1 +----------------------------------AAQYGLSAVQAKVLLRLPAGGATTMQGLAGQLQYDASDLTESWIASSPWGAVRRQPHPEDRRVKRVELTDDGRRMRKAFWEKLTNRSG-PLRRLNSRELISLRALLATA--------- +>tr|A0A094IE95|A0A094IE95_9MOLU Transcriptional regulator SlyA OS=Mollicutes bacterium HR2 GN=slyA PE=4 SV=1 +--------------------------------------ELTKNEIKTLMQLKFRGRQSLSYYSEKIGLKKGSFTSLTDKLEEKGLIKKSYIEHDKRKKIIIPTQKGIELTDKFYNSFVNHLSIKISKLSDSDLVLMESAINILSKIDLS--- +>tr|A0A1Q9N8M6|A0A1Q9N8M6_9ARCH Uncharacterized protein OS=Candidatus Heimdallarchaeota archaeon LC_3 GN=HeimC3_02450 PE=4 SV=1 +--------------------------------------DISSKEFQILYLISNYEPCNLTKISEIVQYPNSTVCRIIDKLNEAKLIKKHdsKNNSDRRKKKLSPTEKGEKIINIFIKQHIKISTFIVGDIPNQNLALVLEKLKKFFSHF----- +>tr|A0A239ZB11|A0A239ZB11_CLOCO Transcriptional regulator OS=Clostridium cochlearium GN=SAMEA4530647_00381 PE=4 SV=1 +--------------------------------------KISPYPVIILNQLDISKPTTLTDIRERLGIPNSTISTVVDKLLEKELVRKEKDATDKRRTFLYLTEKACEEEKKIIKQHVEVFKEILCKATEDDLNTLIDATKLFIKLIEE--- +>tr|E4SHP0|E4SHP0_CALK2 Transcriptional regulator, MarR family OS=Caldicellulosiruptor kronotskyensis (strain DSM 18902 / VKM B-2412 / 2002) GN=Calkro_ +---------------------LSLFPMITKNILKkdefSEKYGLPPRFIHILHITDVFGPMNMSELAKRLNISAPNLTPIVDKLIAEGYVQRLKDESDRRISIVQTTEKGKELLSLHTQWVNQNLEKNLSRLSEDEIEELWYLLKRLKTLVLK--- +>tr|A0A101GUM0|A0A101GUM0_9FIRM Transcriptional regulator, MarR family OS=Desulfotomaculum sp. 46_80 GN=XD84_0992 PE=4 SV=1 +---------------------HIVLEYIRENFFRpvdqVTRSRLSHVQFCAMSILCRRGSLSMSELADEMRISKQQLTPLIRKLIDRKMLSRKTDPDDRRIVRLEVTGIGRSTLEDLFNELKMALVEKLKELPVAELDELGQMLKRILDILKS--- +>tr|H3KA03|H3KA03_9FIRM Uncharacterized protein OS=Megamonas funiformis YIT 11815 GN=HMPREF9454_02076 PE=4 SV=1 +---------------------FDIMMTYNHKLWRTAALPLPLNHFAVMYYLFEkEDTfATVTELAKHLSISKQQMSPIIDKLVKKEFIKKTCLSKDRRYSQISLSEKGRNFLKEHQKSQRLIFMESMTDLSDSDTEKFDQSVRLVKKMMAK--- +>tr|G2G278|G2G278_9FIRM MarR family protein OS=Desulfosporosinus sp. OT GN=DOT_6119 PE=4 SV=1 +---------------------SNLVPLFARRLLRpleqEAKNLTSPVHMHTMTVLCEKEYFTMTELSNEMTMSKQQMTPIIDKLVANGYVQRKHDTIDRRSIKICLTSVGIDFLNNINNEVTNILKKKIECLDTDDLASLNDALDNLFRIINK--- +>tr|A0A0L8F1L0|A0A0L8F1L0_9CLOT Uncharacterized protein OS=Clostridium sp. DMHC 10 GN=AGR56_14685 PE=4 SV=1 +---------------------FSVMPVFSKIILNvgdkvLKENGIAVAHIKVIYMVKRYKKINITDLGKALSSPKSNVTSWTNKLVKMGFVQRVFDEKDRRVIYIKLTDKGEAFFQFYEEALRKSFEEKLWKLSDEDLKLFKDTLDNMRKLVDK--- +>tr|A0A1C3CIE4|A0A1C3CIE4_PAEPO Transcriptional regulator OS=Paenibacillus polymyxa GN=A7312_03795 PE=4 SV=1 +---------------------LGLFPIVKKKFFTygplDFPLHLSPNNFQVLMLLREVRSSTVSDLSKQLNVSRPNMTPLLDKLVEHGLADRQSCDSDRRVVNVAITQEGDAFCEQVFHTFSNKIQERLVYLPEEDLLHLSETLNELKHILLK--- +>tr|A0A1V5PAY6|A0A1V5PAY6_9BACT Transcriptional repressor MprA OS=bacterium ADurb.Bin363 GN=mprA_5 PE=4 SV=1 +---------------------SQLCTDMAEKFFQaiyrrpSKADQIPLSHLKVLMFLSKKESFKMKDITEELGIASSSATDLIDKLIKEHLVERYRKPDDRRVVKVKLSEKGRNLIVELKEMKRKFWVTIIENISEEDREDLVRYHRKFYNIIGK--- +>tr|L7VPC8|L7VPC8_CLOSH Transcriptional regulator MarR family OS=Clostridium stercorarium subsp. stercorarium (strain ATCC 35414 / DSM 8532 / NCIMB 117 +---------------------------------VLEDSALTFHQVYVMKIIGAKTDVNLTSLCKELNLSKGAMSLTVNRLEEEGYVKKCENPSDRRNRNIVLTPKGEEVLNSTREKLREAFDKLTKDLTIEELENIKNSLMRLNETM----- +>tr|C9YJN2|C9YJN2_PEPDR MarR-family transcriptional regulator OS=Peptoclostridium difficile (strain R20291) GN=CDR20291_0782 PE=4 SV=1 +---------------------------------NFKENGLTHQQIIVIKLVAHNQELTISQLCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQESFDDIFKNCDENELSDLVKNLRNILAKV----- +>tr|G6BA47|G6BA47_CLODI Transcriptional regulator, MarR family OS=Peptoclostridium difficile 002-P50-2011 GN=HMPREF1122_02728 PE=4 SV=1 +---------------------------------------ISLVELSILEIVEQHPNSMMKEISSTLELPKSTLTSAVKRLELKKLIKRNPCIKDKRAYNLDLTELGLKAQQEHREIEATVFKNILHQLDKDEIETFIHIFSKAVNKI----- +>tr|A0A0L8EP44|A0A0L8EP44_9BURK MarR family transcriptional regulator OS=Achromobacter sp. DMS1 GN=AD428_15215 PE=4 SV=1 +---------LERFLTYRLHAVNKISDRDTARAY-LADCGIPLGEARCLAAIGRYAPLSVNELARAANLNKGQASRSAQALVERGLVEKKNSDTDGRGVVLAPTPSGQAQYERIIALISRRNAEIFGCLSAEEQRQFGDMLDRL--------- +>tr|V4YMP8|V4YMP8_9PROT DNA-binding transcriptional repressor MarR OS=Betaproteobacteria bacterium MOLA814 GN=MOLA814_00048 PE=4 SV=1 +---------LDRTFTHRLHTLSKLTDRVTQATY-ESRADIGLSEGRCLAAVGAFRPLSINDLAARANLDKAQASRAAQALVARGWVNKVTGMKDRRGVLLTLTPEGNSRWSKLKRVISDRNAEIVACLDDGEQTLFSTLLDRL--------- +>tr|A0A1L6LHG7|A0A1L6LHG7_9DELT Uncharacterized protein OS=Minicystis rosea GN=A7982_06487 PE=4 SV=1 +-------------FIDTFGAVKRCITAAAGQAY--AALEIGSTQAKFLRHIGKHSRISQAELARATETDPGLTGRTLQSLIERGWVLRARSDEDRREYVLELGPEGRRAVARVEKQRLQLGERVVAALDERDLDDFDRIAKKI--------- +>tr|A0A089HKP6|A0A089HKP6_PAEDU Uncharacterized protein OS=Paenibacillus durus GN=PDUR_11910 PE=4 SV=1 +-------------------------------------SGLTVHQLDILRLIRTAPRLTQKEVTERLRMPKSRVSLHIDALVDKEFAVRETSPQDRRETLLRSTPAGETLCEHYdrdDLSR-KALAGALRQFSPEEIELLLTMHERLLNEL----- +>tr|A0A1S2QNC2|A0A1S2QNC2_9BACI Uncharacterized protein OS=Bacillus sp. MUM 116 GN=BIV60_26940 PE=4 SV=1 +-------------------------------------LGITTVQLKVIHKLASNPDISLGELAEKLRMTSSTASSVIERLVQIGLVERVTPPENRRVVSIHLTEKGKKILDQFyssDSIFIKKTND-VLKLSERDISELIRLQKIILKKLSI--- +>tr|A0A1Q4BE26|A0A1Q4BE26_9RHIZ Uncharacterized protein OS=Rhizobiales bacterium 62-17 GN=BGP04_12725 PE=4 SV=1 +-----------YAMVQCTSRLLACRDAFGND------LSLTASQFAVLmgvAYRQNSEGVTIKELAEHVALASTHVTTEVGRLERKGLLLKRQNAADRRSVHVSLSTKGEEAIAHVSPLVRMVNDTLFEGIDPEALETARQVARQLILNSDEALA +>tr|A0A1Q4DMT0|A0A1Q4DMT0_9RHIZ Uncharacterized protein OS=Rhizobiales bacterium 64-17 GN=BGP08_17965 PE=4 SV=1 +-----------ADLFAAAAGMLALRRALATT------VDLSAAEFAILlatWQQEQKGEVGISSLAREVHVAAANVTAEVGKLVRKRILHKQPHPRDTRAVLINLTDKGHEILARLTPVLQEINDRLFVGNSTRDITVVGNFLHHVADETPYSIN +>tr|A0A158L205|A0A158L205_9BURK MarR family transcriptional regulator OS=Caballeronia terrestris GN=AWB67_07256 PE=4 SV=1 +-----------NGLLPFAARLLSVRDGFGTI------IGLTGIQYSLLvsvAHLSHGEAVTVNRLADHLHLSGAFVTIETGKLKKLGLIDKRSDPDDKRKMRLTMTSNGVKLLRELAATQQRINNVLFEGVTKAEFKALCSVVDRLVANGDRATL +>tr|A0A193KZ39|A0A193KZ39_9ACTN MarR family transcriptional regulator OS=Streptomyces sp. SAT1 GN=A8713_035585 PE=4 SV=1 +---------------------------------------LDRSAYVLLTRLETGEPLTLKELAHTFQADVSTINRQMSAMLRHGLVERIEATTKGGARTFRPTPLGLERLAADRAISRAGAARLIeaAGWSPERTQQFLTLMIEFNHGIEQ--- +>tr|A0A1A9DGP8|A0A1A9DGP8_9ACTN Transcriptional regulator OS=Streptomyces sp. MnatMP-M77 GN=YW3DRAFT_07040 PE=4 SV=1 +---------------------------------------LDRSAYVLLTRMETGEPLTLKELAHTFQADVSTIHRQVGTMLRHGLVERIDAATRAGARTFRPTPLGLERLEADRAISRAGAARLIeaAGWSDARTQEFLTLMVEFNHGIER--- +>tr|A0A0X8L4C4|A0A0X8L4C4_9BURK Uncharacterized protein OS=Burkholderia sp. PAMC 26561 GN=AXG89_07175 PE=4 SV=1 +----------------------------------TEQSALSPTEWRVLFAVMHAGTAIAADLSRTLQINTGYLSRLLNDFERSGLIVRSPYAGDARSRHISLAPAGESVLAATSTHVRNNVSTALEAMTPDEGSQLMASMELV--------- +>tr|J4K9M4|J4K9M4_9FIRM CodY helix-turn-helix-like domain protein OS=Peptostreptococcaceae bacterium AS15 GN=HMPREF1142_1167 PE=4 SV=1 +------------------GKLMEIVNDFSDLFSTWDCYdEFTKRDTCILTMILVHTrqgnKITTSNISDLLGITKPAISQALKKLEQGGFVRRKVNNDDRRVVYVYLTKKGEQRLRKKDELFQSHIDDALSKMEDEEVNLLIKYADKF--------- +>tr|A0A098B5G3|A0A098B5G3_DESHA MarR family transcriptional regulator OS=Desulfitobacterium hafniense GN=AT727_20975 PE=4 SV=1 +------------------VRLLESIKKFRQLSLNFRGNgEIPHREIMMLKLIKHHSgegGITISSLSAHLEISKPAVSQMINSLEDKNYVERITPKSDRRMVYVRLTELGEEALGVAFHEMQKKLEIYLEKMGEEDMATLIALLDKL--------- +>tr|A0A161YU68|A0A161YU68_9GAMM Uncharacterized protein OS=Marinomonas sp. TW1 GN=OA79_07785 PE=4 SV=1 +------------------------------------------VDWRMLFLLALRPGATAAEASKTFGVDKGTVSRSVSRLTKGGLIVSGDLHANGRSRGLFLSSSGREMHDQLLAATLDQHHFLMKGFDEAEVKVFCDFLLRFTANLEDLS- +>tr|A0A0M4GRM9|A0A0M4GRM9_9BACI Uncharacterized protein OS=Bacillus sp. FJAT-18017 GN=AM500_17370 PE=4 SV=1 +-------------------------------------------------RLQEEQG---aarvSDLSSGLDILLPNMTKLLKEMEGQQLVEKYRPPIDKRVVQIRMTSQGEQYFNDRVLPYRNQVLKELDNLETADVETMIRTIHQIQDILHRVYA +>tr|R6RJQ5|R6RJQ5_9FIRM MarR family transcriptional regulator OS=Firmicutes bacterium CAG:424 GN=BN652_02031 PE=4 SV=1 +-------------------------------------------------EITCKQE---sctvSNIRDRMQITMPSISKLIQELEALHMIEKEADREDRRFYQLKLTWEGTDCVKKHVLDFHKEWAKRLAYVENQKVEEAVNLFTELRNTMPGGEV +>tr|A0A1V8QE99|A0A1V8QE99_BIFLN MarR family transcriptional regulator OS=Bifidobacterium longum GN=B5780_1797 PE=4 SV=1 +-------------------------------------------------HINEQNGQDIgtarvGDVSAFLGVTTPSITKLVGEMADLGLVVKHADATDRRAVTLTLTERGLDIRRIYVEEYRAHLSQLLGGLTVDQCETTVRTLTEALRLMQQDAN +>tr|A0A095BFE2|A0A095BFE2_LEUME Transcriptional regulator OS=Leuconostoc mesenteroides P45 GN=LH61_08450 PE=4 SV=1 +-------------------------------------------------------------FADKAKISKPAATRIIHRFVAEKYLVKRPSTVDKRTSYLELSAEMKINCEKNRQLFDQVFLDSISVLTPEEQTVLHKIMFKINEKI----- +>tr|A0A094JPM3|A0A094JPM3_9BACL Uncharacterized protein OS=Thermoactinomyces sp. Gus2-1 GN=JS81_10410 PE=4 SV=1 +-----------DNLIGLFHQIMALCHLLL--REELKKHHLTFSHALVLHFLNVKGASPLVEISKHLDIPLSSLSGMIGRLEEMGMVLRKRDQKDRRIVQIRLTDKSREMIDELSDSQRNKIYAhvKRLNLSSEEMERFIENMQRF--------- +>tr|A0A081BIE2|A0A081BIE2_9LACO MarR family transcriptional regulator OS=Lactobacillus oryzae JCM 18671 GN=LOSG293_120470 PE=4 SV=1 +-----------------------------------KQANLTISEWELLNRVTA-ENNTQELLSKLMDLDTSTLSRQLKNLVTKEMLDKTATGKDHRQLIYDVTEKGDQAKASIQEQVQRLDTTIFEHWSDEEKQLLQILLNRLAKSVNR--- +>tr|A0A0R1Y958|A0A0R1Y958_9LACO Uncharacterized protein OS=Lactobacillus aviarius subsp. aviarius DSM 20655 GN=FC33_GL000504 PE=4 SV=1 +-----------------------------------KNNQLTIAEWQLLQRIAD-GKNSQELLAEDLRLDTSTLSRQLSKLTTKAFVKISKVanqnnVKTRKSYQYHLSEIGQRVLSQMNTDFKEFGQKVFAQWTGEEKNFLKILINRLTQSMRQ--- +>tr|E0NDL9|E0NDL9_PEDAC Transcriptional regulator, MarR family OS=Pediococcus acidilactici DSM 20284 GN=HMPREF0623_0391 PE=4 SV=1 +-----------------------------------YEMTGTVADWKMVNYVND-ARLTTLNLVELSGLDKSTVSRQLKHAIQHNFLQKQSNEIDQRKSTFTITDKGDTLRTYVNQKMAEFDRHLFDNWSEEESAMFQILINRVLKNALK--- +>tr|A0A0A1PMQ0|A0A0A1PMQ0_9BACT MarR family protein OS=bacterium YEK0313 GN=BN1110_04673 PE=4 SV=1 +-------------------LAARRIARRLEQGMAEAGMPLA--QFWLMAQIASSPDDRLGALAGRMGLDPSSLSRNLKVIERRGWVEIALAEADQRRRVVWLTEQGARALEAALPAWHAAHEALAAAMPQ----GFGQGLSRL--------- +>tr|A0A158IVA2|A0A158IVA2_9BURK MarR family transcriptional regulator OS=Caballeronia cordobensis GN=AWB70_05457 PE=4 SV=1 +-------------------RLSRLLTGLYNAKMKDVPLSIS--QYTLIVNIEALAPARVTEVAKALLMDRTSVTRLTEPLITRGLLMIEQSEEDRRVKNLTVTTKGRNALRASEQAWQEAQLAFYEAVGPEQWKLLRKTLRDT--------- +>tr|A0A1V6GYF6|A0A1V6GYF6_9BACT Putative HTH-type transcriptional regulator YusO OS=Thermotogae bacterium ADurb.Bin062 GN=yusO_2 PE=4 SV=1 +--------------------------------------NLKTSELFILLFLYLKGPKSMNQLSRFLNTTKSNMTALIDQMERRDLLKREHSKVDRRVIDVSLKAKGRQICEEASDGFNVLVQAFFKKVNKEDLPIISQGFMCLHRLATE--- +>tr|A0A1A0CUW7|A0A1A0CUW7_BACIU Putative HTH-type transcriptional regulator YdgG OS=Bacillus subtilis GN=SRCM101280_04193 PE=4 SV=1 +--------------------------------------HISREQADLLKILKVKGPTSPGSLAMYQNVHKSAISNRLKKLLEKGLVQWDDCpeKSDRRSKLINITPSGEHILEELDSAIFNALKPLIDDIDEEHLHSIIEIFTIL--------- +>tr|A0A060M3I9|A0A060M3I9_9BACI HTH-type transcription regulator OS=Bacillus lehensis G1 GN=BleG1_2531 PE=4 SV=1 +--------------------------------------DLSPEQLAVLIIIDLTGPLTSKEIAEYQRTHKSAVSNRLKKLQQKNLIQFKESDKDSRLKYVHFSEEGKAKMKAYQEEVHTYFTALFSDFEAQEVAQFYQLMNKI--------- +>tr|C4FBB0|C4FBB0_9ACTN Transcriptional regulator, MarR family OS=Collinsella intestinalis DSM 13280 GN=COLINT_03364 PE=4 SV=1 +---------------------------FCGHYMHFHGGGRSGQIPILCMLDRCGGTLSQQELGMRFEIKPGSLSEILSKMETAGLIERTRDTKDRRQLFVHLTDEGTRLAHLEHEKRDRFRRSAFAALTVEEQEQLAEMLEKIRVT------ +>tr|G1WKD2|G1WKD2_9ACTN Uncharacterized protein OS=Collinsella tanakaei YIT 12063 GN=HMPREF9452_01752 PE=4 SV=1 +---------------------------FCGHYMHFHRGGRSGRAPILCLLEKNGGTMSQQALGASFDLKAGSLSEILSKMEGGGLITRTRDRQDRRQLTVCLTEAGAEAARLETEARIRFRTRAFSNLTPEEQDQLADLLDRVKSR------ +>tr|A0A1X9TWY7|A0A1X9TWY7_9LACO MarR family transcriptional regulator OS=Lactobacillus delbrueckii subsp. delbrueckii GN=B9N98_09750 PE=4 SV=1 +---------------------------QMGMRYEKLHGGVRGQNRTLALLSK-NEGMKQVELARFARVRPSSISKVVDRLERYGLIERRRDNSDHRVFRLYLTEKGREQNKRNHSSWLGFVGDLMSPLSDDEKAEYLNILKKPDKQ------ +>tr|A0A0S3KCP1|A0A0S3KCP1_9ENTE MarR family transcriptional regulator OS=Enterococcus silesiacus GN=ATZ33_12005 PE=4 SV=1 +-------------------------------------------------------------VSEKLSFTKPAISAMVKRLEGLDFIEKHQSSIDKRIYNLLITEKGKNIVEGDNSLYQQFTEKVRELTTEDQMKQFTCLLEKLTAQL----- +>tr|V5WH60|V5WH60_9SPIO Transcriptional regulator, MarR family OS=Salinispira pacifica GN=L21SP2_1497 PE=4 SV=1 +----------------------------------LEGEDVTSKQLFLMIVVGNFGEKGPtvTQAAEKAGSSYQNVKKLALHLERSGYLRIVSDEDDRRAKRLVMTRRAKDFWQQREQQDARNFMELFRDFRFGELEKFNEYLLRLESQIEKSIR +>tr|A0A1V6IMX4|A0A1V6IMX4_9EURY Transcriptional repressor MprA OS=Euryarchaeota archaeon ADurb.Bin023 GN=BWX56_00769 PE=4 SV=1 +----------------------------------LRKDDLTTKQWQLIAAIGKYFTYPPsiSEIAEVLSTTHQNIKQIALKLQEKEFIAIEKDQKDKRVLRLRLTEKNRRYWESNKDEDEAFIRSLFNSLTDNEIKELYYLLNKLEENINQMYD +>tr|A0A174ASP3|A0A174ASP3_9FIRM Transcriptional repressor MprA OS=Faecalicatena contorta GN=ERS852491_00823 PE=4 SV=1 +------------------------------------DEEITMKQWLLLAMAGTTEN-PMslTDLGRLMGCSRQNVKKIAHSLEQKGFLRLERREGDSRAVCVVLDEKVKAYTDRVGEMQQGVLKLLFRGFSDNETSVLYQGIMKLQENISEIEN +>tr|A0A1Y4FAJ7|A0A1Y4FAJ7_9FIRM MarR family transcriptional regulator OS=Blautia sp. An249 GN=B5F53_03105 PE=4 SV=1 +-------------------------------------NEMSCKQWLLMSVLKAFDT-PPdlSTVAKAMGCSRQNVKQLARPLEQEGYIRLEKSKEDARSLCISYTEKGRQFSKENTAKGKFVHEAVFSEFSEDEIDIYYSLSIKMMNGIKHLEE +>tr|A0A0I9QG01|A0A0I9QG01_KLEVA Transcriptional regulator, MarR family OS=Klebsiella variicola GN=BN1200_880007 PE=4 SV=1 +--------------------------------------PHTWSTMLLLSAIDHaEDGITPGELARSEDFRTSNLATMLKGLEARGLIVRIKDSDDRRRVRVYLTETARQLLSENRRKRDEWLFKAMIdGLKQEEVDVLLKAGEIMK-------- +>tr|A0A0Q7KLR3|A0A0Q7KLR3_9ACTN Uncharacterized protein OS=Aeromicrobium sp. Root472D3 GN=ASD10_06945 PE=4 SV=1 +--------------------------------------DLTPTQLSVLGAICQLGEATPGAIAALERVQPPSITRTLASLVEAGMAIRTPHPDDGRQVLMSVSERGDAVLAEERDRRDLWLSHALDELTPAERRTLEEAAVLLE-------- +>tr|A0A1E7XVR0|A0A1E7XVR0_9PROT Uncharacterized protein OS=Acidithiobacillus ferrivorans GN=A4U49_03380 PE=4 SV=1 +--------------------------------------ALGLSQIGVIARLHQt-GPMTTADLARIEFMKPQSMGTNLSDLERLKLVQRERHPTDGRQVLYSLTQEGIEERNHRRSTKKAWLAGAMEi-LRPEELEILARVIPIIQ-------- +>tr|A0A097CRN5|A0A097CRN5_9ACTN MarR family transcriptional regulator OS=Verrucosispora sp. MS100047 GN=VASRM7_57 PE=4 SV=1 +----------------------------------------------------------------------------MTDLCAVAEVVADPPPSRRRP-ATRATRSGTPRRTAE--------------------------------------- +>tr|A0A1Q4ZPQ8|A0A1Q4ZPQ8_9ACTN Uncharacterized protein OS=Streptomyces sp. MJM1172 GN=AMK15_35180 PE=4 SV=1 +----------------------------------LEARASGLLHQSILKVLADLGPHARRDLAAQVDAPPAEASRVMDDLQSQGLVQALVVNVGGRQEVLALTAAGTAARATALDHVKGVQDVLLASLTKGERAQLHYLLRRV--------- +>tr|A0A1S8YPY0|A0A1S8YPY0_9ENTR MarR family transcriptional regulator OS=Izhakiella sp. D4N98 GN=BTJ39_06480 PE=4 SV=1 +----------------------------------VGDSQLTAVQFITLCALRDHGPSAQNDLVRFTAVDQATIRGVVERLKARDLVSLGPDPKDKRKVIVMLTTEGQRLTSQVTTNAMRISEMTYGQLNPAERIALVYLLRKM--------- +>tr|A0A0D8HCP0|A0A0D8HCP0_9ACTN Multiple antibiotic resistance protein MarR OS=Acidithrix ferrooxidans GN=marR PE=4 SV=1 +------------------------------------NRDIDMNTFWQLSPLR-sGVPLRPSEIANAIGLDSSTVSRALQKLEAQGLIERRIDPSDARAHLIALSAEGATVLEIVGNARREKIATVLSHCTHSEIPSEEGLIRNVDGAI----- +>tr|A0A1C4LC61|A0A1C4LC61_9ACTN DNA-binding transcriptional regulator, MarR family OS=Streptomyces sp. SolWspMP-5a-2 GN=GA0115242_112514 PE=4 SV=1 +------------------------------------GVPIDRSSLALLRALAAaPSPYRMGDLAEVLLVQASHVTRQARGLEEAGLVTTVKEPGDdHRVRRITITQNGRDVVARAEATGQLWLTGALHGFTQEQLSVAAAVIQRVTDVY----- +>tr|A0A1T4YLL5|A0A1T4YLL5_9MICO DNA-binding transcriptional regulator, MarR family OS=Agreia sp. VKM Ac-2052 GN=SAMN06295879_3549 PE=4 SV=1 +------------------------------------EVPVRDGTYPILT-TL-aSGEARSTDIAERAGVDRTTASRQLASLIAVGLVDQRTDNNDRRNSLLALTPRGVATADRISDNADDMLEQALADWSLSDREALARLLPRLLSAL----- +>tr|A0A1F4E7T4|A0A1F4E7T4_9BURK Transcriptional regulator OS=Burkholderiales bacterium RIFCSPHIGHO2_01_FULL_64_960 GN=A2710_05040 PE=4 SV=1 +--------------------------------------------MDVLQTIFWSAGASRNALAQRLAYSKSKANAMVAALLDEGLLDEVGLQESSggrRAETLRLSETLG--------------------------------------------- +>tr|A0A1H0YKI7|A0A1H0YKI7_9MICO Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain OS=Leucobacter chromiiresistens GN=SAMN04488565_0955 +-----------------------------------------SNQGALVEALRQRGALSKMQLSELTGLSAATVNRVLKGLIEHGFVAQAGTEESTggrPAVLFDVVPTAL--------------------------------------------- +>tr|A0A1Q8LRB4|A0A1Q8LRB4_9PSEU Putative ROK-family transcriptional regulator OS=Pseudonocardia sp. Ae717_Ps2 GN=Ae717Ps2_2218c PE=4 SV=1 +-----------------------------------------RNRELVLSSIQQHPNVTRSQIAELLGLPRTTVTAAVASLVSDGRVEENPtRPTHRrgrPAMLLRASEAVR--------------------------------------------- +>tr|A0A126YM16|A0A126YM16_9BURK HxlR family transcriptional regulator OS=Burkholderia sp. PAMC 28687 GN=AX768_16725 PE=4 SV=1 +------------------------------------------SRWGVLVLMVLLDEQMcrFSDLRRKVdGVSEKMLAQTLQWLAADGFVVRTSYDVVPPHVDYRLTPLGKEVARQVSSLADWIEINLARIMGARA-------------------- +>tr|C7RS71|C7RS71_ACCPU Uncharacterized protein OS=Accumulibacter phosphatis (strain UW-1) GN=CAP2UW1_2608 PE=4 SV=1 +---------------------------------------------ELLRTLPANGeFFPQWEVKAalatqEKRFSDSRLSQLLGQIEDHGLIGHRKR---GKYKDWRLTESGQQVLAK---------------------------------------- +>tr|A0A0Q4I758|A0A0Q4I758_9SPHN LysR family transcriptional regulator OS=Sphingobium sp. Leaf26 GN=ASE85_12310 PE=4 SV=1 +---------------------------------------------------------SFSRVGREVHASHTTIARRLDLVEAHfgvRLFHRTTR-------RLVPTADADQLLVHVRTMLDALDL------------------------------ +>tr|A3JY52|A3JY52_9RHOB Transcriptional regulator, ArsR family protein OS=Sagittula stellata E-37 GN=SSE37_20572 PE=4 SV=1 +----------------------------------------------VIERLAR-GPAAVSDLHDGHDMALPSFLKHLNKLEAAGIVR---SIKTGRTRMVHIEPAPLAAAEDWLIRQRNIWEGRLDRL------------------------ +>tr|T3D7H3|T3D7H3_CLODI HxlR-like helix-turn-helix family protein OS=Clostridioides difficile CD160 GN=QEW_3633 PE=4 SV=1 +------------------------------------------------------------------ECSKKMLTQQLDFLIEQEIIVKKKRLVNNIvESTYFLSESGLLLLPVMEKMIM---------------------------------- +>tr|A0A1J4V5C8|A0A1J4V5C8_9BACT Uncharacterized protein OS=Candidatus Hydrogenedentes bacterium CG1_02_42_14 GN=AUJ18_06755 PE=4 SV=1 +----------------------------------------------VLKILAEKPAVSLLELkkkikltppltpphfyknGEGLGERKNyALARLIKNLVESGYAEMRQSD---NQSYLKITKKGKNKLNciklegdeaLVPRVWDGFWRIIILDIPEErknEREALRYLLKK---------- +>tr|D3F751|D3F751_CONWI Uncharacterized protein OS=Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577) GN=Cwoe_0386 PE=4 SV=1 +-------------------------------------KELSIGEWAVLALLCERPmhGYaiaaamaPDGEIGQIWSLGQPLTYRALSVMQRLELVEVNAFkPGDRAprRTELRANARARRMVSR---------------------------------------- +>tr|A0A0R2QSS2|A0A0R2QSS2_9ACTN Uncharacterized protein OS=Acidimicrobiia bacterium BACL6 MAG-120910-bin40 GN=ABR78_04190 PE=4 SV=1 +-------------------------------------YEPSVLDQIVLAIIGEIPrhGFavskeleTDPSLAAVIRIRRPLVYRSINSLLNAKFIRETKVePGDQGspRVIYATTATGKSTTAK---------------------------------------- +>tr|A0A094QP44|A0A094QP44_9ZZZZ Uncharacterized protein OS=freshwater metagenome GN=GM51_12660 PE=4 SV=1 +-------------------------------------QDAQLARDVVLALVVLTPrhGWavheelaPSGTIGRAWTLSRQLVYRAIDTLVADGFVKRATPkDG-GGadKVIVSPTAAGKRHVEM---------------------------------------- +>tr|A0A1F8L5Q4|A0A1F8L5Q4_9CHLR Uncharacterized protein OS=Chloroflexi bacterium GWB2_54_36 GN=A2X24_04360 PE=4 SV=1 +-------------------------------------QAPLSTEYILLGLAAKGPvhGYdlhkqlgTLDGLSSIWRVKQSQVYALLDKLENMGYLHGEAVPGTAAvlRKQYQLTAAGQQAFEA---------------------------------------- +>tr|A0A069IL45|A0A069IL45_9BURK Uncharacterized protein OS=Cupriavidus sp. SK-3 GN=CF70_022220 PE=4 SV=1 +-----------ESVLLALMDSVREWQRVLDQTL--SDVGLDYAKWILLRAIRQGEFVRHEPWLGPMLISAPQSESLLRTLHADRWIEFDPAG------QPFIPAGAVPRVERVWSGMKALHSVSVAPFSTEERTALTASLRRMKATLHDHS- +>tr|X1N2C2|X1N2C2_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S06H3_49809 PE=4 SV=1 +------------------------------------QLELNSRQIKAVAYLQKKGKIARSEYVKLTKCSPKTANNDLHEMLDKQLIKQKGGGKYTFYVLTHV-------------------------------------------------- +>tr|A0A0G0IIN7|A0A0G0IIN7_9BACT Uncharacterized protein (Fragment) OS=Microgenomates group bacterium GW2011_GWC1_37_12b GN=US39_C0019G0007 PE=4 SV=1 +------------------------------------QIALSERQMKLIEYLTEIGGAGMQDLKkQLKMVSEDTILRDLTKLIEKGILKKEGHTKASKYVVVTK-------------------------------------------------- +>tr|A0A1F5ZW50|A0A1F5ZW50_9BACT Uncharacterized protein OS=Candidatus Gottesmanbacteria bacterium RIFCSPHIGHO2_02_FULL_39_11 GN=A3D77_06145 PE=4 SV=1 +------------------------------------RNVLDNDELRLVDFAISLGRITSSDAVDILKVPKRTAQSKLKRLEDIKVLTKHGAGPATYYIVTPL-------------------------------------------------- +>tr|A0A1F5YFP7|A0A1F5YFP7_9BACT Uncharacterized protein OS=Candidatus Gottesmanbacteria bacterium RBG_16_38_7b GN=A2153_04225 PE=4 SV=1 +------------------------------------EKELLPHHQTIISYLKEKGFIKDRNYARLTNRAKATRILDFKKLMNMGIIERLGKGKNTYYTLKTS-------------------------------------------------- +>tr|A0A0C1GYN6|A0A0C1GYN6_9BACT Uncharacterized protein OS=Candidatus Protochlamydia amoebophila GN=DB44_GG00010 PE=4 SV=1 +------------------------------------EYKLSKRQKLALDCLLeRKENFSIRNYElLCPGINRRSLQRDLSDLIEKKLISQDGIKKASRYKVNRL-------------------------------------------------- +>tr|F8AMP4|F8AMP4_METOI Transcriptional regulator, PadR-like family OS=Methanothermococcus okinawensis (strain DSM 14208 / JCM 11175 / IH1) GN=Metok_09 +--------------------------------------------LLILYLLDKEDlhGYAlMQKLSELFINYkpsSGVIYPTLQGLKRSGYIEYVKFEADeksrnenknnenenenkknnHSKKLYRITDKGREYLKENDKKLKRIFEHInnINEFYDLGGKSLKEAMTIVIKEIPNLSE +>tr|E0SQI5|E0SQI5_IGNAA Transcriptional regulator, PadR-like family OS=Ignisphaera aggregans (strain DSM 17230 / JCM 13409 / AQ1.S1) GN=Igag_1439 PE=4 +--------------------------------------------YLVLYAIDNlKKayGYEiRRFIRSILKLYtpsTGILYPTLHELEKEGILMSYKEG---RRRVYMLTEYGRKLLERDREKIYSYVGKLryAtEILEKLDIDKLINIVKVLWENNIVLSP +>tr|E0SQM7|E0SQM7_IGNAA Transcriptional regulator, PadR-like family OS=Ignisphaera aggregans (strain DSM 17230 / JCM 13409 / AQ1.S1) GN=Igag_0252 PE=4 +--------------------------------------------LLILKILSESPmhAYGiLKRLREITGHEelsVGVLYPVLRTLINKGLVDIRIDRVDgEERKVYYVTDKGKKLLDERASSVDEALRVAnrFKILKSIEVDRVFRTIRSLFEIADSLSE +>tr|B8D3Z1|B8D3Z1_DESA1 Transcriptional regulator, PadR-like family OS=Desulfurococcus amylolyticus (strain DSM 18924 / JCM 16383 / VKM B-2413 / 1221n) +--------------------------------------------LLILDMSRGGRihGYYlLKKIREETGLPvnPGLIYPLLKGMVEKGLIKAEESFEKgRRKIVFRITEKGEKYLEENKQELEIARKYFekLKLAKEVGLTKLVARLIRIFEKIDQLTP +>tr|A7NQR4|A7NQR4_ROSCS Iron (Metal) dependent repressor, DtxR family OS=Roseiflexus castenholzii (strain DSM 13941 / HLO8) GN=Rcas_3874 PE=4 SV=1 +----------------------------------------SVEMYLVMTALLRSapdQPVPLSLLASKLGVSQVSANEMCHRLEERGLLSYQPY------KGVTLTPDGEEWAQRILSRRRLWVIFLVEnlGIDPEEADTLACQLEHI--------- +>tr|A0A0N2QP32|A0A0N2QP32_BORPT LysR substrate-binding domain protein OS=Bordetella pertussis H921 GN=L548_2381 PE=4 SV=1 +---------------------------------------PSFAQLGVFHAIMITSSVSRA--ARLMGMTQSAASKMLRQLEDDTGLRLF----ERQHQRLVPTPHAQGLQDSVEQLYGAYGV------------------------------ +>tr|A0A1M6VZJ8|A0A1M6VZJ8_9BACL Transcriptional regulator, LysR family OS=Alicyclobacillus sp. USBA-503 GN=SAMN05443507_1258 PE=4 SV=1 +---------------------------------------KRLELYQALVQIVENETLVQA--AQVLNTTQPTLTRQLQQLEHRlgvRLFDRIGR-------RLVMNHAGELAYQYAKRILQTEER------------------------------ +>tr|A0A0U5D108|A0A0U5D108_9EURY Homolog to phage PhiH1 repressor protein OS=Halobacterium hubeiense GN=HHUB_3508 PE=4 SV=1 +---------------------------------------MTPVDRDILERLWNERNrdlqLTPSMIAENVDWGHQAVREHVLTLHEHDLIEYA----DEDRGVYKLSKRGRKWLE----------------------------------------- +>tr|A0A1Q9NWB6|A0A1Q9NWB6_9ARCH Uncharacterized protein OS=Candidatus Heimdallarchaeota archaeon LC_3 GN=HeimC3_09400 PE=4 SV=1 +-----------------------------------------------------GESMFVSKLAKNyqekfelnglKKISRSAIRKHIEILKEYGFIKPVNE--GGKPEFLQVTEIGMKAIKKFEK------------------------------------- +>tr|C9MSE6|C9MSE6_9BACT Fic family protein OS=Prevotella veroralis F0319 GN=HMPREF0973_02565 PE=4 SV=1 +--------------------------------------KWSikpslaAKLVDIIYFANNHQELTTELITREFQLTPTTAKRYLRQLVSFGFLQSEGANRNRKYRALGN-------------------------------------------------- +>tr|A0A1V6BXV5|A0A1V6BXV5_9BACT DNA-binding transcriptional activator FucR OS=Bacteroidetes bacterium ADurb.Bin139 GN=BWX93_01205 PE=4 SV=1 +--------------------------------------KISSRQAGIIDLIRIDSSVTTDDLARKICVSSKTIKRDIAVLKQQGILLREGSDKKGKWIISVP-------------------------------------------------- +>tr|A0A1V5S0Q0|A0A1V5S0Q0_9BACT Fic/DOC family protein OS=Bacteroidetes bacterium ADurb.Bin302 GN=BWY47_01161 PE=4 SV=1 +-----------------------------------------vnssDMDSQLLTLIKEHPEYTYEEYAQKLNVGRATIARHIKKLS-GTMIERIGSDKNGYWVLIK--------------------------------------------------- +>tr|A0A1C5QNU2|A0A1C5QNU2_9FIRM HTH-type transcriptional activator CmpR OS=uncultured Ruminococcus sp. GN=cmpR_2 PE=4 SV=1 +---------------------------------------MDISKYALFADVADTGNFTKS--GERMGYTQPGVSHILKAMESE--FGFPLFVRTKQGV--VPTHNAEAILPLVRQLLAVNEQLE---------------------------- +>tr|A0A1V1YNW0|A0A1V1YNW0_9ACTN LysR family transcriptional regulator (Fragment) OS=Streptomyces sp. WAC00263 GN=BOG92_22825 PE=4 SV=1 +---------------------------------------LLAPRLAYFAGVARTEHVTRA--AQEMRVPQSTLSRAMVRLEQD--LGVDLFARRGRTV--SLTPAGRTFLSSVERALAEIERAA---------------------------- +>tr|A0A1M7REE0|A0A1M7REE0_9ACTN Transcriptional regulator PadR-like family protein OS=Cryptosporangium aurantiacum GN=SAMN05443668_110301 PE=4 SV=1 +----------------------------------MRDVEMTLAIARLLKAFLEDPLRPrhGYDLMRSTGFASGKIYPLLAKLQTAGWLTRERESVDpaavgrPARRLYRLSDEGTQAAWHALD------------------------------------- +>tr|A0A0K2SGW4|A0A0K2SGW4_9FIRM Uncharacterized protein OS=Limnochorda pilosa GN=LIP_0410 PE=4 SV=1 +----------------------------------------------ILRTMHEEGACTRTSLARTTKMSPATVSRIIGQLMGHGIVReesRIPSSAGRKPVLLRIDYAKLPIV------------------------------------------ +>tr|A0A0M0TMJ7|A0A0M0TMJ7_9FLAO AsnC family transcriptional regulator OS=Flavobacterium sp. VMW GN=AKO67_09385 PE=4 SV=1 +--------------------------------------SLDEFDINIIKELEKDGRMAFSAIAANLKISNTMVHQRINRLMEQGIIGGIKPIIQEKKIGFDWAS------------------------------------------------ +>tr|A0A0Q4R1A8|A0A0Q4R1A8_9SPHN PAS domain S-box protein OS=Sphingomonas sp. Leaf242 GN=ASF09_19090 PE=4 SV=1 +----------------------------------------------VAIYLAEAEGrvVGVERLASETRMAPSTTRRWITALQQEGIIWDDSNVVA----DVQFTQSGITRMEGMLASVFQ--------------------------------- +>tr|A0A0Q5UKX6|A0A0Q5UKX6_9SPHN Uncharacterized protein OS=Sphingomonas sp. Leaf198 GN=ASG20_09320 PE=4 SV=1 +----------------------------------------------LSVYVAEAESriATVDSVASQLGLNRATLDRWIRVLEAKSLVDPPDSMRE----ALQLTRSGIDDVERLLSTRSL--------------------------------- +>tr|A0A0G1MTY6|A0A0G1MTY6_9BACT Transcriptional regulator, TrmB OS=Candidatus Peregrinibacteria bacterium GW2011_GWA2_44_7 GN=UW70_C0034G0016 PE=4 SV=1 +----------------------------------LREIGFSDKEIKVYLAALKLGMQPASVLAKHLKMNRVTTYVICKKLIEKGVANALTRNN----------------------------------------------------------- +>tr|A0A0G0QY35|A0A0G0QY35_9BACT Transcriptional regulator, TrmB OS=Parcubacteria group bacterium GW2011_GWB1_40_14 GN=UT82_C0032G0017 PE=4 SV=1 +----------------------------------LENIGLSRKEAKIYLALLDYPESTLADIVRKTRMPRMTCHSILEKLFTGGFIDIIIKRK----------------------------------------------------------- +>tr|A0A1G2AQR1|A0A1G2AQR1_9BACT Uncharacterized protein OS=Candidatus Kerfeldbacteria bacterium RIFCSPHIGHO2_02_FULL_42_14 GN=A3B74_00095 PE=4 SV=1 +----------------------------------LKGLDFTDKQIDIYLYLLREVRASAKQIYESLHLNKVTAYKVLDELVEMDVIGVIHGED----------------------------------------------------------- +>tr|A0A1F5WQD6|A0A1F5WQD6_9BACT Uncharacterized protein OS=Candidatus Giovannonibacteria bacterium RIFCSPHIGHO2_12_FULL_43_15 GN=A3F23_00640 PE=4 SV=1 +----------------------------------LKKLGLSEGEAVAYSYLLENGESSVGQMIKKLPIKRGNLYNVLRGLVFKGLAEEFKKNK----------------------------------------------------------- +>tr|A0A1F8H881|A0A1F8H881_9BACT Uncharacterized protein OS=Candidatus Yanofskybacteria bacterium RIFCSPLOWO2_02_FULL_47_9b GN=A3I39_01770 PE=4 SV=1 +----------------------------------AEVFNMSLNEAKVYLALNNQGSSMVSRVGKSANLPRTAVYPPLMSLVKRGFVGTTVSGK----------------------------------------------------------- +>tr|A0A1X2BVQ3|A0A1X2BVQ3_9MYCO Transcriptional regulator OS=Mycobacterium saskatchewanense GN=AWC23_22395 PE=4 SV=1 +----------------------------------LVEAGLEPKEARFYLAALSMDSATVAQVAEASQISRTNAYDIAKRLAQRGLLSLIEGGS----------------------------------------------------------- +>tr|Q1GES2|Q1GES2_RUEST Transcriptional regulator, IclR family OS=Ruegeria sp. (strain TM1040) GN=TM1040_2112 PE=4 SV=1 +--------------------------------------------IEILETLAREGAMSLADLHRATGLPKSTLRRLLQTLIARKIVRRSLA--DKLyRTLVVFPDISGEVMPKGMLHISEAAIPRALALTKE--------------------- +>tr|H5X8L5|H5X8L5_9PSEU Transcriptional regulator OS=Saccharomonospora marina XMU15 GN=SacmaDRAFT_3156 PE=4 SV=1 +--------------------------------------------LRVLRVLQEMRAASLHDLHLATGIPKASLTRILHTCHREGLVWQRMA--DGAfLPSHIQQRRA-KIDD--AEWLVEIASPVLKRLCEQ--------------------- +>tr|A0A089J565|A0A089J565_9BACL Uncharacterized protein OS=Paenibacillus sp. FSL P4-0081 GN=P40081_18135 PE=4 SV=1 +---------------------------------------------QLEYFLAVCEEMHFTRATDKVRISQPSLSQQIRNLEYEVGTPLF----DRIGKKIALTEAGKILKHHSQNIFYELNQ------------------------------ +>tr|F7SBJ4|F7SBJ4_9PROT Uncharacterized protein OS=Acidiphilium sp. PM GN=APM_3852 PE=4 SV=1 +---------------------------------------LTAKRWDILQAMTGHGEMAIREVARQVDRDVKAVHGDVQALLTAGVLDRTDS------------------------------------------------------------- +>tr|E7N4Q4|E7N4Q4_9FIRM Fic family protein OS=Selenomonas artemidis F0399 GN=HMPREF9555_01999 PE=4 SV=1 +------VNAAVSGTEKNLREKKDRYDVYYSRIQ--K-l-EVDRTLKELYDVLLQAtifsgaG-VSKKELMRMLDKSENTITARMKAMPS-GVlRENRT----VRPFTYALNLKVFDEP------------------------------------------ +>tr|S4HAS7|S4HAS7_GARVA Fic family protein OS=Gardnerella vaginalis JCP7275 GN=HMPREF1572_01283 PE=4 SV=1 +------IVKAQGEVFENINLQLKQTIYCMDKLFEFSKkTAISKVQYEVMTILLQNklfsynPtPMTRKQLSEYVGnaigeqVGERKIVSALNGLIELEMVDSIG----ERPLRYELSKKANEMF------------------------------------------ +>tr|W4N9C4|W4N9C4_9BIFI Cell division protein Fic OS=Bifidobacterium moukalabense DSM 27321 GN=BMOU_1172 PE=4 SV=1 +------IERAQTSLIDELGVKIDQLGKAGDLRDELENel-KLSHNATCLLYAVMQEelfdttKSMTLEEAGADLMLTKQTMRKYVEELDRAGLIEFTG----RRPLRFGASESLRGKM------------------------------------------ +>tr|T2I184|T2I184_BIFLN Fic/DOC family protein OS=Bifidobacterium longum subsp. longum CECT 7347 GN=BN57_893 PE=4 SV=1 +------VADAQKKLIDDLSEKGYMLLHAVNRL----EslkeeRQWDDVEANIIAVLVQEelfgesPhRVTRRQLGEGLGLGRKKITQGLGSLEETEAVSHKg-----TRPAFYSLTDEIRARL------------------------------------------ +>tr|A0A0H0YL18|A0A0H0YL18_LACCA Uncharacterized protein OS=Lactobacillus casei GN=AAW28_08645 PE=4 SV=1 +------IETGQKDIIAALKQSQVKLEDWFKRILA---ADFTDHQKAILAYLIQPylfgsrE-NSTmddNALKELLSrqgfngrtYSQVSIKKSIDQLEKDGWIELVK----HRPKIHAVSQRFIAYM------------------------------------------ +>tr|D5P131|D5P131_CORAM Fic family protein OS=Corynebacterium ammoniagenes DSM 20306 GN=HMPREF0281_02321 PE=4 SV=1 +------LVDAMEELLDSLVKKNSQLSIMREQVATLISedpsvdDALDEKESDILFLLGQVhlfgprSGMTMDELCQVMGRTRRSLRSVTVRLRERGLIRELK----KSPLVFALTDEAIELV------------------------------------------ +>tr|A0A0U1A2M9|A0A0U1A2M9_9MYCO Filamentation induced by cAMP protein fic OS=Mycobacterium abscessus GN=ERS075547_00755 PE=4 SV=1 +------IAEAQHRLLLDLSDRRQKIDTVAACIRVLVEdeqfplniglireaepPVDPKDIGVILFVLGQAhhfdvnRAVKLKTLADAMDRSIQFARPRLQRLDDAGIIETVT----RKPLRFRLTQRGASLL------------------------------------------ +>tr|A0A086Z272|A0A086Z272_9BIFI Fic family protein OS=Bifidobacterium actinocoloniiforme DSM 22766 GN=BACT_1326 PE=4 SV=1 +------IQEAQDDFMKAFGRQLEERTQISPLC----EsigreRGLTGPATRILESVFREavlgtrKGVGLGDLSQELGRSKQSVRIHVGELLEKGLAVYTk-----RRPLMITVSHAALGRF------------------------------------------ +>tr|A0A0F4LNB3|A0A0F4LNB3_9LACO Fic family protein OS=Lactobacillus apis GN=JF72_12890 PE=4 SV=1 +------LSDGQDEVIDQLQKARYRLDYVKKELEK---RKYSIVKFNELYIYSQAylfndfE-GSIedRELFELFKqdhISRRKFKEGLAELQNEGLIETVK----AKPLKRRITAKFLEQI------------------------------------------ +>tr|X8ITT0|X8ITT0_9FIRM Fic/DOC family protein OS=Mogibacterium timidum ATCC 33093 GN=HMPREF0581_0975 PE=4 SV=1 +------IKESAINLKAGLTEKSERLNVLKKGFLGNL-pn-GQEGKYTDLYYFLLQAslfseiG-ISTKSLIENLNVSRPTLQKRLHEIDENNLlVTEIE----DRNKFYKLNLDTLVEK------------------------------------------ +>tr|K0YID9|K0YID9_9ACTN Uncharacterized protein OS=Slackia piriformis YIT 12062 GN=HMPREF9451_01729 PE=4 SV=1 +------VLTGMERLREALAERDVNLRKYEALAWELYGe-QGDKSSYELMRILIVArlfalyG-VMSDELCEVLDITKPTLQRRFRPLKDAGLvRVERV----GHKVYYACELDELERR------------------------------------------ +>tr|U2SS80|U2SS80_9FIRM Fic family protein OS=Mitsuokella sp. oral taxon 131 str. W9106 GN=HMPREF1985_01901 PE=4 SV=1 +------IQKSIHRVHDILQEKGKKLFSLEKAVKASP-d-IPSQKERKIYDILLQAylfsdeG-ATVEEIAHTLGQSTRTIRTHLTRYPA-DHiEVDPS----HKAHRYKLSEHFVQKL------------------------------------------ +>tr|F8DZ17|F8DZ17_CORRG Uncharacterized protein OS=Corynebacterium resistens (strain DSM 45100 / JCM 12819 / GTC 2026) GN=CRES_0597 PE=4 SV=1 +------LHEAQLDILTSLLEKRSLLESVHRRLSNEK---LSNYSHGILYSLAQVtlfgseETLTLSEIVSVSPYSWNTLRKEAELLVKKQLLIPVS----KRPLTYALAPVARKFL------------------------------------------ +>tr|T4C0E2|T4C0E2_CLODI Fic/DOC family protein OS=Peptoclostridium difficile F501 GN=QOE_2572 PE=4 SV=1 +------IVSAMESMRNSLRELRNMLEEGERMAEIVFA--KDEKAIEIASVLVTAalfafnG-ITMAELTYTFDASRQTMYKKLAPFKERGVlVAQKE----GRKTYYRMDLDALRRL------------------------------------------ +>tr|A0A0Q1DVX0|A0A0Q1DVX0_9CORY Adenosine monophosphate-protein transferase SoFic OS=Corynebacterium sp. NML 130210 GN=Cocul_01137 PE=4 SV=1 +------VHTAQRNLSAEISERKQSLDTLWSSVEQLSNr--FEEQEMAILFVLGQAhlfnseSGILHRTVVEYVPTGDRQTRRWTTRLQERGLVELRG----ERPLRYGLTAESRNLL------------------------------------------ +>tr|R7AZC4|R7AZC4_9FIRM Uncharacterized conserved protein OS=Ruminococcus sp. CAG:379 GN=BN633_01571 PE=4 SV=1 +------IRTSSESLNASLLKRLEKMTFFRNQLLKRF-pn----DRHFRVLHILMLNtlfgyrG-LTLPELAAACGMDEPLTAVLLQTLAtQTPLvVLYRE----GEHTMYEVNLERLAEI------------------------------------------ +>tr|D7BPH5|D7BPH5_ARCHD Filamentation induced by cAMP protein Fic OS=Arcanobacterium haemolyticum (strain ATCC 9345 / DSM 20595 / NBRC 15585 / NCTC 845 +------IRDTQQDLILQLEEALKRLLSVQMRLDQCN---VDSDCSTILWILAQAelfsggTTMERRELEQYVEKSTPTINRYIKQLVADGWVEIVA----QRPVTIRLSDEGAPRL------------------------------------------ +>tr|A0A0R1WK16|A0A0R1WK16_9LACO Fic family protein OS=Lactobacillus nantensis DSM 16982 GN=FD31_GL002284 PE=4 SV=1 +------ILEGQISVLEKLNELLDLLNKYFAELKEILNvnDTNNDLEFNLLFVFIESklfnvdS-SLGvkdTPLINMLYkrdtrlYKKVKIREIIKKYEDSGILVKVG----QKPLQHEIDLEKLFGD------------------------------------------ +>tr|A0A1E9U2K1|A0A1E9U2K1_9CORY Cell filamentation protein Fic OS=Corynebacterium sp. HMSC074C11 GN=HMPREF2614_01865 PE=4 SV=1 +------ILNAQQYLLEELQMKSYQCERLEQRIAELSNspervlpVSLTGNEIGTLYVLAQGrlfgpeYGIKLEHVADTVGKEKRTARKYLAELEAAGLAMPTS----RRPLRFQLAPAGVDLL------------------------------------------ +>tr|A0A1F1V104|A0A1F1V104_9CORY Uncharacterized protein OS=Corynebacterium sp. HMSC08F01 GN=HMPREF3171_00860 PE=4 SV=1 +------LIDAQRDLEESLDQKHFQLHSLHEVLSSVD---RDEYECDLLYLSAQAylfspdLPFSLKDAVSAIGRSWNTIRPVAEKLEAEGLIQSAS----KSPLTLELTAQGREYL------------------------------------------ +>tr|A0A1C4H5Q0|A0A1C4H5Q0_9BIFI Fic family protein OS=Bifidobacterium commune GN=GA0061077_1140 PE=4 SV=1 +------IQIAQRRFNDNLNEKELALNTATNAM----IhyaaeQRLDPMSTDILSILIQQrlflrrEaELTRAMLAGYENVGQARIRSKLELLTRKDLISTVg-----KRPICYQLSNHACELF------------------------------------------ +>tr|A0A172S096|A0A172S096_9ACTN Fic family protein OS=Denitrobacterium detoxificans GN=AAY81_09720 PE=4 SV=1 +------IREAQLAIIKRLEACARKLDELDGIM----GnitsnVKLRSKEAQVIHLLLQYkafglfGDASVQEIADYLGVGKQQARKYIAALEERGICQKLnS----YNPITFKLTDEFIATY------------------------------------------ +>tr|A0A1Q6E1J9|A0A1Q6E1J9_9ACTN Uncharacterized protein OS=Eggerthella sp. 51_9 GN=BHV62_05600 PE=4 SV=1 +------VVDAMESMLDSLQAKQSDLADAVGAVNRAIAtk-EEDAGLWRVAFILAQAdlfsenG-ATTEELCAAAEMSEPTMARKRKLIKELGFlRETRK----GRQRFYSLNLQKMG-------------------------------------------- +>tr|A0A1Q6RGK3|A0A1Q6RGK3_9FIRM Uncharacterized protein OS=Firmicutes bacterium CAG:24053_14 GN=BHW36_09575 PE=4 SV=1 +------IEKSMSALRDALEKRSALLTHYS-LNIGSL-pd-ADSEIIYELYSVLIQArlfsenG-VSMGELCAHLNRSGETVRKKLAVVKNSGLlITKTV----KREKFYGIDLELIDNF------------------------------------------ +>tr|A0A1Q9YNN2|A0A1Q9YNN2_9FIRM Uncharacterized protein OS=Faecalibaculum rodentium GN=BO223_00070 PE=4 SV=1 +------LESALKHEIVKLESQLEKYEQYLSKLNNT---SLKPAEKTFLETLLAAslfslyG-ISKQQMIQITQMSQSWVDKTLKKHR--DKlNVRRE----GHAKWYSMNKEFLATL------------------------------------------ +>tr|A0A1Q6NWC6|A0A1Q6NWC6_9FIRM Uncharacterized protein OS=Eubacterium sp. 45_250 GN=BHW21_02235 PE=4 SV=1 +------VDISMKQLYDEIKNKLDKFNFYG-DLCPKL-pn-ADHKDIERLYYVLIQAalfsenG-ISQNELESFFNVSYSSVRNKLSSIPA-DLlIKNTR----ERHAYYMLDLDKVDIM------------------------------------------ +>tr|A0A1V5HVM4|A0A1V5HVM4_9BACT Adenosine monophosphate-protein transferase SoFic OS=Tenericutes bacterium ADurb.BinA155 GN=BWY98_00660 PE=4 SV=1 +------IDSGYDDTLAYLQKKQNLAEQLRAKTS----pf-VKTAAEKRLMEALLEAsvygdfG-LTVLALSEAGKVGSATVNRFLAKLKKNGVlWIRRF----GKKDYFLFPSPNTSL------------------------------------------- +>tr|A0A229W136|A0A229W136_9BIFI Cell division protein Fic OS=Bifidobacterium sp. Tam10B GN=Tam10B_0037 PE=4 SV=1 +------VNDAQRRIIDDLSEKYGAFERAKAVL----YelsreRGWSDDQVDIVGVLIQEelfgtpPhRVTRPQLQNGLKFGRKRVNTALDPLVESGAMVTMg-----MRPVRYSLADGMRRLL------------------------------------------ +>tr|A0A1Y2SZH8|A0A1Y2SZH8_9BIFI Uncharacterized protein OS=Alloscardovia macacae GN=B9G54_04580 PE=4 SV=1 +------IETAQTSLILHLREKLTILESATQFM----TqhfTDLNTTERNTLEILLQEhlfnryTsGLTRTDIMNALDVGHKKVKNTLDHLAALGYITIEg-----KRPIRYSASTKLRDEL------------------------------------------ +>tr|A0A0S1YFH6|A0A0S1YFH6_9ALTE Transcriptional regulator, Crp/Fnr OS=Alteromonas stellipolaris LMG 21856 GN=AOR13_64 PE=4 SV=1 +---------------FLTRNLAIKLHATLERLDDILRLPTHVQLAKLIYQTSVAQassvetksvqaslsqtstavALRQSDYAERLGVTVLTAHKALNKLVSLSLIRK---------------------------------------------------------------- +>tr|A0A0G3V621|A0A0G3V621_9ACTN Uncharacterized protein OS=Actinobacteria bacterium IMCC26256 GN=IMCC26256_112034 PE=4 SV=1 +----------------------------------------RLDLAPVSSGIVVEN--ELLHTLRLVGSSLDTGGSVSDSIVASGFALRR-------KDRLLLTPSGRVAAEEAAR------------------------------------- +>tr|A0A0M8PRS5|A0A0M8PRS5_RHORH Uncharacterized protein OS=Rhodococcus rhodochrous KG-21 GN=Z051_01280 PE=4 SV=1 +----------------------------------------VPHEINLLQALRLKGRIEIEALPRTLAADPASVDPLVTAHVEAGHCIHK-------GNFLRLTADGKQTLVEWTT------------------------------------- +>tr|A0A0N9HNM9|A0A0N9HNM9_9PSEU Uncharacterized protein OS=Kibdelosporangium phytohabitans GN=AOZ06_18105 PE=4 SV=1 +----------------------------------------VSIAFDVLHALAVKGMAQAGPLAVSSGVSGDELNEELARITEEGLANHMA-----GRGLWRITPDGRAKHAQLLH------------------------------------- +>tr|A0A178WSE4|A0A178WSE4_9PSEU Uncharacterized protein OS=Amycolatopsis sp. M39 GN=A4R44_08061 PE=4 SV=1 +----------------------------------------EKTDYDVLNTITLKKMATPAAVVRASGRDTAEVETAFERLAAQGLVAVA-------SGAALPTDEAEPALLDAAA------------------------------------- +>tr|A0A163Z9K0|A0A163Z9K0_MYCKA Uncharacterized protein OS=Mycobacterium kansasii GN=A4G26_11235 PE=4 SV=1 +----------------------------------------MADELTILRLVAIKGRVPTELVAGSLGVDEERAQALLDDLVEWELVKQT-------SMGYRVTAAGRARCTEFVA------------------------------------- +>tr|A0A0Q9QR53|A0A0Q9QR53_9ACTN Uncharacterized protein OS=Nocardioides sp. Soil777 GN=ASG88_20930 PE=4 SV=1 +----------------------------------------MELRDLVLHALTVKKSGTADQIAEFLGRDSGEIATTLSAAAEDGLVAGG-------AGIHMATPAGRQVLDELYP------------------------------------- +>tr|A0A076F085|A0A076F085_RHOOP Uncharacterized protein OS=Rhodococcus opacus GN=EP51_46300 PE=4 SV=1 +----------------------------------------LDPYELTVHTLTLRQLGSAEQLAEINALPVADVETALEKAVADGAVMAA-------RGNYMITPAGREFLDGVYP------------------------------------- +>tr|A0A0A1VC53|A0A0A1VC53_9BURK Uncharacterized protein OS=Acidovorax sp. MR-S7 GN=AVS7_00918 PE=4 SV=1 +----------------------------------------NAEQHLVLHGLAIKKYAHPDAIASLLDLPPGRVKQVVDEGVAKGTVIDV-------GGKFAVSPAARLSLHANYS------------------------------------- +>tr|A0A1B1H0F7|A0A1B1H0F7_9NOCA Uncharacterized protein OS=Rhodococcus sp. 008 GN=AOT96_32130 PE=4 SV=1 +----------------------------------------PIEAFELLHLLRIRGRVAADQLDTDDAVIEALSETDLIRMTERGAVLTS-------KG---------------FQ------------------------------------- +>tr|A0A1Q7D666|A0A1Q7D666_9ACTN Uncharacterized protein OS=Actinobacteria bacterium 13_2_20CM_2_66_6 GN=AUI15_15355 PE=4 SV=1 +----------------------------------------ADVPDSIVWAMTIKGSAPLDGLASAVGSNPERVQAILNRLLKEGLVERA-------GSSYRLSSKGKLKGRQLLA------------------------------------- +>tr|A0A1V0AHF6|A0A1V0AHF6_9ACTN Transcriptional regulator OS=Nonomuraea sp. ATCC 55076 GN=BKM31_55890 PE=4 SV=1 +----------------------------------------SPLDLLVLHAVRITGYADTPAIAHRYGLDAAETKEVLLDAQAYGWVQHTVAF--GDTGGWSLTERGKAENERLLA------------------------------------- +>tr|A0A1V3ZXX9|A0A1V3ZXX9_RHORH Uncharacterized protein OS=Rhodococcus rhodochrous GN=GQ85_00460 PE=4 SV=1 +----------------------------------------EKDEFEVLHGLRIKGMTQPEEIAEATGLEVDLVTEVLDGAVAQERARHRTG---GKVQGYMLTASGRDRHQSLRA------------------------------------- +>tr|E9T1Q3|E9T1Q3_RHOHA Transcriptional regulator, ArsR family OS=Rhodococcus equi ATCC 33707 GN=HMPREF0724_12100 PE=4 SV=1 +------------------------------------------------------GEHSVSALAEKYDMSFAAVQKHVSVLQNAGLLTKRRR---GREQLASGDVAAVRSVASMLTELEDVWRGRIARIDE---------------------- +>tr|A0A1E3S2Q6|A0A1E3S2Q6_9MYCO Transcriptional regulator OS=Mycobacterium holsaticum GN=BHQ17_01185 PE=4 SV=1 +------------------------------------------------------RERSVTALAAKYDMSFAAVQKHVAVLERAGLISKRRE---GREQLASGDVEAVHSVASMLTELEDVWRGRVAAIDD---------------------- +>tr|A0A1T5AJ03|A0A1T5AJ03_9SPHI DNA-binding transcriptional regulator, ArsR family OS=Pedobacter luteus GN=SAMN05661099_0771 PE=4 SV=1 +------------------------------------------------------QALTPNAMAEKFDMTRQAVSKHIKVLHECELIKPEQS---GREIYYHFNPKKMREFDNWLAQFRHNWEVQFNQLDN---------------------- +>tr|A0A1V0N4T6|A0A1V0N4T6_9EURY Transcriptional regulator OS=Ferroplasma acidiphilum GN=FAD_1280 PE=4 SV=1 +-------------------------------------------SLRILYILNLED-MTGYGLSRKLYNsatgkniSNGALIPVLNRLLSDNFIDFSVR---NGKKYYHLTEKGKKFVGNVLDLNEEVRDQAIFD------------------------- +>tr|A0A0D6ULZ8|A0A0D6ULZ8_STRGR ArsR-family transcriptional regulator OS=Streptomyces griseus GN=BF14_5776 PE=4 SV=1 +---------------------------------------------RILRHLGAAGPATSTTLAAALGENTGTLSYHLRMLERSGLIEDIPERSTGRERWWRGVRGlDIRRPPQGelTEAERAMSAELDRMRMEEDVDLARQFTA----------- +>tr|U5WBV5|U5WBV5_9ACTN ArsR family transcriptional regulator OS=Actinoplanes friuliensis DSM 7358 GN=AFR_41700 PE=4 SV=1 +---------------------------------------------QLVTWLQRHGSATSADLAVEFDADRGATSYHLRQLARFGFVEEDTERSAGRRRYWRAIPQDVRLPRGPaDPELALVADELGRQWMERADRDLTAYLS----------- +>tr|A0A1H1R1J9|A0A1H1R1J9_9ACTN Helix-turn-helix domain-containing protein OS=Jiangella sp. DSM 45060 GN=SAMN04515669_0774 PE=4 SV=1 +---------------------------------------------TLLRLLREDGPATASSLGERIGQSSGVTSYHLRTMAEAGLVVEDASLGNRRDRWWRAAHEatTFSFRVPGqagDTEHLEVaeqyLRMVAQVGYERVLSWISTLVE----------- +>tr|A0A242K0P0|A0A242K0P0_9ENTE Uncharacterized protein OS=Enterococcus sp. 9E7_DIV0242 GN=A5888_003823 PE=4 SV=1 +---------------------------------------------------------NVLRAAEHIYIGHGTASTRIMNLERKlgvILLERQKG-----VRKTVLTSEGESFLPIAQQWAALWSD------------------------------ +>tr|U2TT25|U2TT25_ACISB FCD domain protein OS=Acidaminococcus sp. (strain BV3L6) GN=HMPREF1246_1747 PE=4 SV=1 +--------------------------------------------------IHQGDVITEQSIANELRISRTPVKNAISKLESENFVTTLNG---RGTLVNVLSIADMRDIYNVRTVLEVlALETTIHNLSEKMVQQACESFQNALALykkdksLVSPE- +>tr|F0RTC2|F0RTC2_SPHGB Transcriptional regulator, GntR family OS=Sphaerochaeta globosa (strain ATCC BAA-1886 / DSM 22777 / Buddy) GN=SpiBuddy_2555 PE= +--------------------------------------------------IKPGEYISEKDILESAEIGRTPFREAIIMLQAEHLVEVRPR---HGTFSTRLTRTDVIEVFSMRKMLEPvAVFTYLNRIDVSKLLENDRLMErLSKNA-EEVP- +>tr|A0A0D5NJT0|A0A0D5NJT0_9BACL Uncharacterized protein OS=Paenibacillus beijingensis GN=VN24_12020 PE=4 SV=1 +-----------------------------------------------------EEYTSENNLVLEMGMSRTPIREALNRLQHEGFLKILPN---RGIVFTELLTEERNELVDMRVAVETySLRQAADRIKEDDIKELSRIIELQEEAYRAGD- +>tr|A0A1C6C032|A0A1C6C032_9FIRM Uncharacterized HTH-type transcriptional regulator ydfH OS=uncultured Roseburia sp. GN=ydfH_3 PE=4 SV=1 +--------------------------------------------------YKEGTVMVERKLCDIYNMSRSPIRNALQQLTHEGLLAFIPG---KGVVVPEFTTEDILEVYDLIEILQVyAVKSCISKCTDVTLESLHLVLDKMHKSLKEED- +>tr|E1RC57|E1RC57_SEDSS Transcriptional regulator, GntR family OS=Sediminispirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228) GN=Spirs_0 +--------------------------------------------------MDWGQRIDIIQIAGNYGISRSPVVKAVDRLSMEGFIDILPN---KGSFVARPSLQRINEVTEIRLMLETySLKLSMEKERKKLLQDLQENQ--KLVAEEKNK- +>tr|A0A1G2YSU5|A0A1G2YSU5_9BACT Uncharacterized protein OS=Planctomycetes bacterium GWF2_42_9 GN=A2Y12_06945 PE=4 SV=1 +--------------------------------------------------FSGNHRWSLRTLAQKFKLSMAPVNVAVRQLENEGLLTVSPQ---KGISIKQLTIPQIKEANLIREALEIqAIRLITLKNDENITNSLYEISCKITEAlkT---S- +>tr|A0A1R3XEN9|A0A1R3XEN9_9MICO DNA-binding transcriptional regulator, GntR family OS=Microbacterium sp. RU33B GN=SAMN05880545_3197 PE=4 SV=1 +--------------------------------------------------LRPGDRLVLDEIARDLGISKIPLREALSGLEAAGLVVTSPH---AGPRVAPLPFHEIRGIYLLREQVETlGMQLAVTHIDDAVVEDLRQINEEMRTGLRESD- +>tr|A0A1L9XD90|A0A1L9XD90_ACIBA GntR family transcriptional regulator OS=Acinetobacter baumannii GN=BRY75_13495 PE=4 SV=1 +--------------------------------------------------FPAGKRLIERNLCEELGVSRSVVREVIRQLEVEGLIEVLPK---KGPIVSFLNWDIACQIYDIKLLLEQnAVVACILNIGQ-EKNiEFDKLSYTINNLsyLDEID- +>tr|A0A1W9TDD7|A0A1W9TDD7_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium 4572_123 GN=B6I22_04075 PE=4 SV=1 +--------------------------------------------------LHAGQQLYEKELMREYGIGRTPLREIFHELQRDGLIEILPK---LGTKVVSMDLKMLRETVQLRKELEGlAAELATRNIAPNQLDEFRQLLMDAENIdtsdSEALI- +>tr|A0A1V4M226|A0A1V4M226_9DELT Uncharacterized protein OS=delta proteobacterium ML8_F1 GN=AVO33_09085 PE=4 SV=1 +--------------------------------------------------LVPGSRISERKYSESLNISRAPIREALKELQEQGIITSISY---KGWFVAEYDEADYREISRLRSILEDnLIECIIThghyeDKDLSRLRTLNEELKqIASNHDLDKR- +>tr|V5DZM9|V5DZM9_9GAMM Transcriptional regulator, Crp/Fnr family OS=Methyloglobulus morosus KoM1 GN=MGMO_47c00190 PE=4 SV=1 +----------------LLGVLSEKIRHLTDKVRLMALSNVYERTVKALQAMAVvegnvsviHNRPTQQELASMVGSSREMINKIMHELTKGGYVTVED-------------------------------------------------------------- +>tr|D9PUW8|D9PUW8_METTM Transcriptional regulator OS=Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 8 +----------------------------------------SSIRFRIMVSLLR-SPKTFDEIKGEVKVSLPALYSNIKLLLEEGAITRRGN-------SYSLTSEATLKTLSALKLMNSVR------------------------------- +>tr|A0A124G2Y5|A0A124G2Y5_9EURY Transcriptional regulator, ArsR family OS=Methanosaeta harundinacea GN=XE07_1857 PE=4 SV=1 +----------------------------------------SKVRNKILLCLKD-GAKSTGDLEKEMGIRNTTILHAIKDMTDSDLVTRAEK-------GYGLTNLGKLQAYLLDEMIDFVL------------------------------- +>tr|B6YUK2|B6YUK2_THEON Uncharacterized protein OS=Thermococcus onnurineus (strain NA1) GN=TON_0551 PE=4 SV=1 +----------------------------------------SNVRHKVLLSLSE-GPKILGEIHSQVGSTKSTISHVLSDLMEEMLIIQDPET-----KQYRLTNIGHLVSLQVKNIWGALE------------------------------- +>tr|A0A1V4TEN7|A0A1V4TEN7_9EURY Uncharacterized protein OS=Methanobacterium sp. PtaB.Bin024 GN=A4E25_01387 PE=4 SV=1 +----------------------------------------------------------MEELKKETGITTSTISHNLSNMEKKSITSKIGE-------KYILSPIGNIITCNLIENIKTAG------------------------------- +>tr|A0A1V4YPF5|A0A1V4YPF5_9EURY Uncharacterized protein OS=Methanomethylovorans sp. PtaU1.Bin073 GN=A4E23_00567 PE=4 SV=1 +----------------------------------------SEKRRDLLLFLLE-QPSTLTNIRKKFDVSSPEIALRIREMESANLMYKDPST-----KMYTLTTTGKIIAKSFRPFVDMVD------------------------------- +>tr|A0A1N6HDT8|A0A1N6HDT8_9SPHN Transcriptional regulator PadR-like family protein OS=Sphingorhabdus marina DSM 22363 GN=SAMN02745824_3243 PE=4 SV=1 +---------------------------------------PSKATRSALISLlNASEGKYGYEIMREAGIGPGTLYPMLARLEDQEILVSRWQEASvegrPPRHIYELTKTGRIFAQSLVDATHL--------------------------------- +>tr|A3YEL5|A3YEL5_9GAMM Transcriptional regulator OS=Marinomonas sp. MED121 GN=MED121_04758 PE=4 SV=1 +---------------------------------------INWDDVKFFLALSRSGSARSV--AEEFGMSHSTISRRIDQLEKSLgskLFNRNVS-------GYQMTEDGLALSHYAKEAEEAMKG------------------------------ +>tr|C5ANY6|C5ANY6_BURGB Transcriptional regulator, LysR family OS=Burkholderia glumae (strain BGR1) GN=bglu_4p0520 PE=4 SV=1 +---------------------------------------TEWTDLMVFVEVARGPSLTAA--GQRLGIDLSTVRRRLATLQDTLgreLFQKQGR-------SLSLSVEGERIFHIAQRMEMLASE------------------------------ +>tr|E2CF56|E2CF56_9RHOB LysR family transcriptional regulator OS=Roseibium sp. TrichSKD4 GN=TRICHSKD4_1683 PE=4 SV=1 +---------------------------------------MQTEAIRLFVLAAEKLNISAA--GKKLDMAPAVASSKLAKLEKQLgveLLHRSTR-------KVSLSLEGAEFLFYAKEMLAQEAE------------------------------ +>tr|V8QUB8|V8QUB8_9BURK LysR family transcriptional regulator OS=Advenella kashmirensis W13003 GN=W822_08980 PE=4 SV=1 +---------------------------------------NRFDSLAVFTRVVELGSFAAA--ARDLDISPAMVGNHVRALESWFgapLLLRTTR-------QQTLTDLGHEVTKRSADVLDSMLA------------------------------ +>tr|E1V3U5|E1V3U5_HALED Transcriptional regulator, LysR family OS=Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9) GN= +--------------------------------------KTTLDHWNVFKTVVEQGSFHKA--AEHLERSQSTVSYAVRKLQEQLGASLI----EIRGRKAVLTPIGELLLEDGKAIVEGMLQ------------------------------ +>tr|A0A1B9P122|A0A1B9P122_ALILO LysR family transcriptional regulator OS=Aliivibrio logei GN=A6E04_09430 PE=4 SV=1 +--------------------------------------MFNLQQLETLVLCVECGSFSAA--ARKLGKAQSAVSTAIANLEIDAGIEIF----DRSTRIPTLTPHGKRLYLQSLNLLSQakDIETMIHSFSAGVEDTLTIAINELL-------- +>tr|A0A1Q9P8D5|A0A1Q9P8D5_9ARCH Putative inorganic polyphosphate/ATP-NAD kinase OS=Candidatus Heimdallarchaeota archaeon AB_125 GN=ppnK_2 PE=4 SV=1 +-------------------------------------ERVPPSAKYIFKLLLTEGEMTQKELIESTGLPNRTVRNALSILKEKGVINQRPHLRDARQSIYFVN------------------------------------------------- +>tr|A0A1M5EC75|A0A1M5EC75_9ALTE DNA-binding transcriptional regulator, LysR family OS=Aestuariibacter aggregatus GN=SAMN05216361_0336 PE=4 SV=1 +---------------------------------------MNVNDLKIVLKVAEQKSIKQA--AESMDLLVATASAAVKRVETSLGVTLFQ----RSTRKLKITSAGEQALSQLAQAVALLNQ------------------------------ +>tr|A0A1V3PZ35|A0A1V3PZ35_9GAMM Uncharacterized protein OS=Rhodanobacter sp. C03 GN=B0E48_09230 PE=4 SV=1 +---------------------------------------NRLSDMQLLVDAADLNSLSAA--GRRAGLSPAAASACLQRVEAMLGARLFE----RTTRQLRLTEEGRIYIASCRVAIETMKE------------------------------ +>tr|X1UXC5|X1UXC5_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=S12H4_29384 PE=4 SV=1 +-----------------------------------------ATKLELLQFIYEREVVSRFDVVEKFGYTPGGADSMLAWLKREKLVT------NDRKGEWTISDDG---------------------------------------------- +>tr|R7C2I2|R7C2I2_9BURK Transcriptional regulator ArsR family OS=Sutterella sp. CAG:397 GN=BN641_00495 PE=4 SV=1 +----------------------------------------QPVRLEILEFLAQ-CPRTVETLTDLLQIDYKNVSAHLKVLLQAGLVSVRRF---GRFRQYAISsTEVLHLVVVLQQTARVTEVAA---------------------------- +>tr|I4B9X2|I4B9X2_TURPD Transcriptional regulator, ArsR family OS=Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) GN=Turpa_3442 P +----------------------------------------NPIRLEMLDYLAQ-MECSVEFLAQKCNQKIGNISQHLKTMSRAGLVRSRRE---GIFIYYAQTeVAQ-TLTDALANTAVKSSPAA---------------------------- +>tr|M5S003|M5S003_9PLAN ArsR family transcriptional regulator OS=Rhodopirellula maiorica SM1 GN=RMSM_03570 PE=4 SV=1 +----------------------------------------NPHRLKMISLLAQ-GDKPIDELAKLTNQSLAAASANVKVLRNCHLIATEKR---GRSVYCSLKdPRVAELWLRFRDLGEVVVPEI---------------------------- +>tr|A0A0J6CVH7|A0A0J6CVH7_9BACI ArsR family transcriptional regulator OS=Anaerobacillus macyae GN=AB986_15020 PE=4 SV=1 +----------------------------------------SPKRLELLDLISH-SPKSVESLSQATKMSVSNTSKHLQALLDARLVTFYKE---KNFVFYKLAsPMVVSLLLSIKAVGAEQIDEV---------------------------- +>tr|A0A089UF04|A0A089UF04_9ENTR ArsR family transcriptional regulator OS=Cedecea neteri GN=LH23_02400 PE=4 SV=1 +----------------------------------------NGARIEILEHLAG-GELSVEMLSGLTGMSTASTSQHLQNLRKGNFVASRRD---GKHIIYRLAdGPVRSVIASLRCFAEYNNEAI---------------------------- +>tr|L0HAS1|L0HAS1_METFS Uncharacterized protein OS=Methanoregula formicica (strain DSM 22288 / NBRC 105244 / SMSP) GN=Metfor_0017 PE=4 SV=1 +----------------------------------------TSASLPICEFLSSFPDASRQDIAQRLKTTGSTVSWHMRRLCEARLITSARE---GRTVRYSLTPVAVKVIGDLR-------------------------------------- +>tr|A0A0E3NUT2|A0A0E3NUT2_9EURY Uncharacterized protein OS=Methanosarcina sp. MTP4 GN=MSMTP_0786 PE=4 SV=1 +-----------------------------------PEAYLPEDLKEVLELIRASGNrITQLELRKKSRYSESKVSLMLSDLEERGMIEKFKK---GRGNIIRIQDEHV--------------------------------------------- +>tr|A0A1A8Z5J1|A0A1A8Z5J1_9ACTN Transcriptional regulator, BadM/Rrf2 family OS=Micromonospora narathiwatensis GN=GA0070621_0594 PE=4 SV=1 +--------------------------------------------LRIAMLTAAsPARTTVDELATRLALPRSHVAKVVQRLQRLGVLVTLR----GRSGGVAFAERAGEL------------------------------------------- +>tr|V2VK69|V2VK69_9GAMM Uncharacterized protein OS=Acinetobacter indicus CIP 110367 GN=P253_02037 PE=4 SV=1 +--------------------------------------------LRILLYISPprDLPYTIAEIAQDLHVSQNHLVKIVHFMGKQEWLITTR----GKGGGLRLNPDARDL------------------------------------------- +>tr|B8F6L8|B8F6L8_HAEPS Transcriptional regulator OS=Haemophilus parasuis serovar 5 (strain SH0165) GN=HAPS_1390 PE=4 SV=1 +--------------------------------------------FRVLMYLAHhqDELRTIPQLAESLQVSQNHLVKVVHFMAKQGWLITAR----GKGGGIRISSLILSM------------------------------------------- +>tr|A0A0P7C006|A0A0P7C006_9ACTN Uncharacterized protein OS=Frankia sp. R43 GN=ACG83_24380 PE=4 SV=1 +----------------------------------------LRKQRVLELLAAESPL-SRAEIATRLSLTNRQATYALTRLTSDGLIDRTTKTHSDPHATYRLAKPP---------------------------------------------- +>tr|L8DF86|L8DF86_9NOCA Putative transcriptional regulator OS=Rhodococcus sp. AW25M09 GN=RHODMAR_2241 PE=4 SV=1 +-------------------------------------------RESVEEAIAQMGEAGALELAERAGISRVAVVKQLNALIERGSVRADGV-PRSPKRRYVWLGHG---------------------------------------------- +>tr|C8VVL1|C8VVL1_DESAS Putative transcriptional regulator OS=Desulfotomaculum acetoxidans (strain ATCC 49208 / DSM 771 / VKM B-1644) GN=Dtox_1459 PE=4 +-----------------------------------------ADSKKIWKYVRDNQPVARKEIiKALKGIFTENqIDYRLEKLVENNLIVATNLKEKASNRKYIIK------------------------------------------------- +>tr|A0A0G0MRX2|A0A0G0MRX2_9BACT Uncharacterized protein OS=Candidatus Uhrbacteria bacterium GW2011_GWF2_39_13 GN=UT30_C0037G0002 PE=4 SV=1 +------------------------------------------EEEKVLEYIRKYKSITNAQCREMLGNDDLQkASRILKRMHKNGKLKQGGER---RWAKYTLP------------------------------------------------- +>tr|A0A087CGP5|A0A087CGP5_9BIFI Transcriptional regulator OS=Bifidobacterium psychraerophilum GN=BPSY_1296 PE=4 SV=1 +----------------------------------------KNFAQRIVTLLEQRPSASVRDIMVDLHLSPIAVATGLRALLNKGLVESVTA-QPHPQKQYRLLNPH---------------------------------------------- +>tr|A0A087DTN7|A0A087DTN7_9BIFI Transcriptional regulator OS=Bifidobacterium subtile GN=BISU_2089 PE=4 SV=1 +----------------------------------------DNMRSAILAYLAERQNASTSELANAAGVSTKTIRDYISRLMEEGLAEGIGS-KYSPKRRYRLIASH---------------------------------------------- +>tr|A0A086ZVG7|A0A086ZVG7_9BIFI Transcriptional regulator OS=Bifidobacterium biavatii DSM 23969 GN=BBIA_1740 PE=4 SV=1 +----------------------------------------GDISKAITTVLERHSAMSAKEIMRELQLTPLAATAGLRELLREGRVIPVRF-QEDPAQRYRLNIGH---------------------------------------------- +>tr|F7UZ11|F7UZ11_EEGSY Uncharacterized protein OS=Eggerthella sp. (strain YY7918) GN=EGYY_05410 PE=4 SV=1 +----------------------------------------ESIEYAIIQIAEAKESVSMKELMDALKRSRPTVRKRVANLVARGVLVPTQA-KNSPQQRYRLSARF---------------------------------------------- +>tr|A0A1H2CJJ3|A0A1H2CJJ3_9ACTN ATP-dependent DNA helicase RecG OS=Actinoplanes derwentensis GN=SAMN04489716_5995 PE=4 SV=1 +-----------------------------------------SNERRIWRALDDGPL-PRADIEVATGLSVDIVKRGLQSLRRKGFVTLIGQQR-SRDARWAK-------------------------------------------------- +>tr|A0A1G1LXY8|A0A1G1LXY8_9BACT Uncharacterized protein OS=Omnitrophica WOR_2 bacterium GWA2_53_43 GN=A2Y05_00695 PE=4 SV=1 +----------------------------------------RDRRQEILAIIKGRGECGRREIKEIVPLSSAGIIYWLRKLVQEGKIEPTTDSLKDPGVKYRIKLNK---------------------------------------------- +>tr|A0A1F1J516|A0A1F1J516_9MICC Uncharacterized protein OS=Rothia sp. HMSC067H10 GN=HMPREF2756_06790 PE=4 SV=1 +----------------------------------------QGRNELILSLLRGHELSIleLLEGleKQGVRVARPTLTKDLNELVSRGSVEATAP-PRSKNRTYRIPR------------------------------------------------ +>tr|A0A1J4TL27|A0A1J4TL27_9BACT Uncharacterized protein OS=Elusimicrobia bacterium CG1_02_63_36 GN=AUJ52_01135 PE=4 SV=1 +-------------------------------------------PKMVYSIIQNDGPIRALTIAEECGISKAYVKLIVRDLLKSKLIETMEKNPRSPKQAYRVKSFH---------------------------------------------- +>tr|A0A021X7F5|A0A021X7F5_9RHIZ Transcriptional regulator, GntR family OS=Shinella sp. DD12 GN=SHLA_73c000220 PE=4 SV=1 +----------------------------------------------MLGVLPAGAALTELDLAAHFACSQGTVREALLQLQEEGLVRRQGH---RGTQVSECTEAEAVEMFRVRLQVECsGIVRTLQAPSRTLVGDLKALFAEMLDAAKVGDE +>tr|A0A1S2DSW1|A0A1S2DSW1_AGRVI GntR family transcriptional regulator OS=Agrobacterium vitis GN=BBK77_10670 PE=4 SV=1 +----------------------------------------------MLGLLPAGAALTELELAAHFSCSQGTVREALLQLQEEGLVLRNGH---RGTQVSQCTEAEAVEMFRVRQQIECnGIIRVMGARSASLVPDLRGLLADMLEAAQAGDE +>tr|A0A1E2S2S1|A0A1E2S2S1_9RHIZ Uncharacterized protein OS=Methyloligella halotolerans GN=A7A08_00456 PE=4 SV=1 +----------------------------YRRFIQRAGLELRPQELWLLNRLSVIVGARSEHLAEALRHPQERLVAPLASLQRQGLVSGGDD-------SLTVTEEGRAVLIKIERARTDSLTELFSEWAPGGHYEIQRILDKFTKTLSK--- +>tr|A0A1Q8E5W1|A0A1Q8E5W1_9STRE PadR family transcriptional regulator OS=Streptococcus cuniculi GN=BU202_08905 PE=4 SV=1 +------------------------RRNGMEEKIRRVYLPMTETAFYILFALQEERhGYDITQKTkeltgGQVVISPGTMYGTLSKMEKDGLIAFIRE--EEKRKLYLITELGREILEIEKARIERLYRNSRGEKYETA-------------------- +>tr|A0A1V4HN17|A0A1V4HN17_9BACL PadR family transcriptional regulator OS=Paenibacillus ferrarius GN=BC351_21990 PE=4 SV=1 +---------------------------MNKDKIQRNYLPMSETAYYILLSLIKTRhGYGIMQHVeeitkGRIKLGPGTLYGSLSKMEKDTLIHVIAE--EDRRKVYQITALGRNILTQEIARLSELFHNSKSVEDDQH-------------------- +>tr|A0A1T8WCV3|A0A1T8WCV3_9MYCO Uncharacterized protein conserved in archaea OS=Mycobacterium abscessus subsp. massiliense GN=SAMEA2275645_05749 PE=4 SV=1 +-------------------------------------------------------GLSNKDLSVGLGLTPSQVSRDIDDLVASGLVIKLENGNYAYgIKTLQIAERFRKQQERLNARLQELENRIY--------------------------- +>tr|A0A0H6ZBM4|A0A0H6ZBM4_VIBCL IclR family transcriptional regulator OS=Vibrio cholerae GN=BTY66_06300 PE=4 SV=1 +----------------------------------------TTIALVILETLFEYGikGATFRDIGFKTQIPRATLHRYLTALVDAGWVEACGS---KQNMVWKPSNHFIKLAFTYRNAVRAEVDRIgaeFRELTGEDL------------------- +>tr|A0A0B1ZK18|A0A0B1ZK18_9SPHN Uncharacterized protein OS=Novosphingobium malaysiense GN=LK12_11595 PE=4 SV=1 +--------------------------------------------LRTIDAISEQQPIGVSALAQLLGDDRSAMQRTVLTLSDAGWIRLAPGtpkkwELTPHLFSIANLArSGDALRRKARTVLNRLCEE----------------------------- +>tr|A0A0D8HQ52|A0A0D8HQ52_9NOCA Acetate operon repressor OS=Rhodococcus sp. AD45 GN=iclR_5 PE=4 SV=1 +--------------------------------------------CRLFEAIARMQPVGVSDLARDIGIDKSAAHRLAITLHSARWLERTEDgrwSISPAILPTFRESAATTLVTGTRPLLEAARDQ----------------------------- +>tr|A0A0B1ZUA1|A0A0B1ZUA1_9SPHN Uncharacterized protein OS=Novosphingobium malaysiense GN=LK12_06120 PE=4 SV=1 +--------------------------------------------LSVFESIAHAQPIGVSALARLLEADKSAVQRDLMTLADAGWIRPAPGlagqwELSPHVLTLARPPhSNESLRLRAGPILERLRTE----------------------------- +>tr|A0A1Q9QZB1|A0A1Q9QZB1_9PSED Uncharacterized protein OS=Pseudomonas sp. GM4FR GN=PSEMO_48790 PE=4 SV=1 +--------------------------------------------FRLLDELTAaRRPLGVTELAQLLQTAKPRTYRHLASMRQLGILEQDPAsekyMLGARLVAYGEAAgEQFDLRAIADPYLTRIRDA----------------------------- +>tr|A0A136Q514|A0A136Q514_9FIRM ROK family protein OS=Christensenella minuta GN=HMPREF3293_01461 PE=4 SV=1 +----------------------------------------------ILRLLKKNNVCSRAKLAKQSGLKQATITNIINDFLNWGLVNETgiiSGEKGRSSIGIQINHQNYYVI------------------------------------------ +>tr|A0A0M2NCK2|A0A0M2NCK2_9FIRM Mlc, transcriptional repressor of MalT and manXYZ operon OS=Catabacter hongkongensis GN=CHK_2297 PE=4 SV=1 +----------------------------------------------ILKLLQRNRLCSRARLAKQSGLKQATITNIINDFISWDIVRETgsiEGKKGRRSIGLTINDQKFFVV------------------------------------------ +>tr|A0A1Y4EPK4|A0A1Y4EPK4_9FIRM Uncharacterized protein OS=Anaeromassilibacillus sp. An250 GN=B5F54_16400 PE=4 SV=1 +----------------------------------------------IIDLLRQQGVCSRATLAHLSGLKQATITNIIAECITSGLVMETglmSGSKGRRSIGITLNEEHCHVI------------------------------------------ +>tr|A0A0A1Y9S2|A0A0A1Y9S2_9SPHN Uncharacterized protein OS=Sphingomonas sp. BHC-A GN=AI27_06435 PE=4 SV=1 +---------------------------------------MTERETMLVGIVRECteaalPVPSIDDIAERLGVaNGGTVPELFRRLHDMGVIINKPF---QRGRQVCLVETGK--------------------------------------------- +>tr|A0A239KC79|A0A239KC79_9SPHN Uncharacterized protein OS=Sphingomonas laterariae GN=SAMN06295912_1505 PE=4 SV=1 +--------------------------------------DPRLAEALVFTAVAEAadvgaPCPSNQDLADIIDGSVSSPPYILTRLQRQGLIAIERY---QKERRITIVETGK--------------------------------------------- +>tr|A0A0F7D195|A0A0F7D195_SERFO Uncharacterized protein OS=Serratia fonticola GN=WN53_05345 PE=4 SV=1 +----------------------------------LSIRSASLRDFEIIKAIIEKGSATQA--AESLGISQPAVSKAVASIEEKlgkTLFTREKG-------RLNPTKDALFFYEEIVNIFNSLER------------------------------ +>tr|A0A1Y6IXZ6|A0A1Y6IXZ6_9VIBR HTH-type transcriptional regulator CynR OS=Vibrio mangrovi GN=cynR_3 PE=4 SV=1 +----------------------------------LSGSWATLRELEIIKTIIEVKTVTSA--AEILGVSQPAISRALTQIETKsgvKFFNRKSG-------KLIPTSNAIALYDEILVIYNSFSK------------------------------ +>tr|A0A150JD15|A0A150JD15_9EURY Bacterial regulatory protein, arsR family OS=Arc I group archaeon ADurb1013_Bin02101 GN=AN188_00358 PE=4 SV=1 +--------------------------------------------ALILKYVISNP-SNANRISLATGIEYKTVQHHLNILEKNGLLSAIGD---KYGKTYFPSELLDRNINNFNEICKNM-------------------------------- +>tr|A0A150J328|A0A150J328_9EURY Bacterial regulatory protein, arsR family OS=Arc I group archaeon U1lsi0528_Bin055 GN=AMQ22_01305 PE=4 SV=1 +--------------------------------------------ALILKYVISSP-SNANRISIATGIEYKTVQHHLSILEKNGLLSSVGD---KYGKTYFPSELLDKNISSFNEICKNM-------------------------------- +>tr|A0A089ZUV5|A0A089ZUV5_METFO ArsR family transcriptional regulator OS=Methanobacterium formicicum GN=BRM9_0521 PE=4 SV=1 +--------------------------------------------ARIIDELNSRP-YNANQLAKCLKLDYKTVKHHLNVLIKNNIVTACGEG--HYGTVYMLSATMEKNYDSFKKIWKES-------------------------------- +>tr|A0A1J6XG86|A0A1J6XG86_9GAMM LysR family transcriptional regulator OS=Acinetobacter sp. AR2-3 GN=BFN00_13890 PE=4 SV=1 +-------------------------------------------------FVKVMETGSISLAADQLFITQPAVTKRIHSLEEYFGVKLF----ESAGRGVQATHAAHSLLPKVKNWLNELGD------------------------------ +>tr|F4FEE5|F4FEE5_VERMA ArsR family transcriptional regulator OS=Verrucosispora maris (strain AB-18-032) GN=VAB18032_25565 PE=4 SV=1 +---------------------------------------LGGTRAAVLRQlgEPG--RHTTTTVSRLVGISVSSASEHTAALRGAGLVDSERV---GGAKVHRLTPLGIHLLA----------------------------------------- +>tr|J2I6V4|J2I6V4_9RHIZ Transcriptional regulator OS=Rhizobium sp. CF122 GN=PMI09_04445 PE=4 SV=1 +MDlakfEGKYIASRTQSALYLGAKFASLFRLEVQMGATARRVALDDFDRQILAILQKDNMTPQRTIGEAVNLSAPAVQRRMKRMTEAGVIQANVAIVDPAALGHPIT------------------------------------------------- +>tr|X4ZQH2|X4ZQH2_9BACL GntR family transcriptional regulator OS=Paenibacillus sabinae T27 GN=PSAB_19185 PE=4 SV=1 +-------------------------------------------ELIIKREFPPEHKLSIPELSTQLGVSRTPIRDALGRLEKDGLIKTVPK---VGTFVVGVSAENVLDIMETRLMIELWVVEKLAAGKAEASPNIIANMEKIHE------- +>tr|A0A078KV78|A0A078KV78_9FIRM Transcriptional regulator, GntR family protein OS=[Clostridium] cellulosi GN=CCDG5_1993 PE=4 SV=1 +-------------------------------------------DEITFLIIPPNQRISEIEVAKRFNVSRTPIRDVFKRLEVEGFLKIIPQ---KGTYVTRIDMSDLADMMYLREKIELAVVEDLCGKlSQDQIIRLQFQIAQQKK------- +>tr|A0A0F2SDK9|A0A0F2SDK9_9FIRM Uncharacterized protein OS=Peptococcaceae bacterium BRH_c23 GN=VR66_15320 PE=4 SV=1 +---------------------------------------LSNAELIILSLVNEKPsyayeiekQIETKSMRLWVRIGIASIYQVLTRLNGKGYLEFKIEREGKApeRKRYCITESGQEILKS---------------------------------------- +>tr|A0A0P0N4C5|A0A0P0N4C5_9CREN Uncharacterized protein OS=Pyrodictium delaneyi GN=Pyrde_1703 PE=4 SV=1 +---------------------------------------------ILEILSKSKNGLTFDEIYNALLEhdsnvKKETIRETLAGLVRRGIIIREPDYERKKMV------------------------------------------------------ +>tr|A0A1F7Q4V0|A0A1F7Q4V0_9BACT Uncharacterized protein OS=Candidatus Saccharibacteria bacterium RIFCSPHIGHO2_01_FULL_46_30 GN=A2791_01860 PE=4 SV=1 +-----------------------------------KGQKLTGQQQRVLKLLFKFRFVSAGLLADVMGIHRVSVYEVLEQLVSKKLVAKVYEPKfriDRKPAYYYLNKSGVTAVRKLMDVKESVVHALYKN------------------------- +>tr|A0A1J5I1M5|A0A1J5I1M5_9BACT Uncharacterized protein OS=Candidatus Saccharibacteria bacterium CG2_30_41_52 GN=AUK57_00705 PE=4 SV=1 +-----------------------------------RYNKLNAKQLHILTLIYKFRFISIPLLTEYQNLKSQTtLLRNLKILEEQGYIGRRFDLTfkiDRKPAYYYLAAKGIAVLKDDPRFDTGVLHSYYKN------------------------- +>tr|A0A0V8RUC4|A0A0V8RUC4_PYROC Uncharacterized protein OS=Pyrodictium occultum GN=CF15_01805 PE=4 SV=1 +------------------------------------GGGLTPSQAAVLLAVYR-GVDRVEELARALRLPRETVEDIVGELEAMGMLEEYRSGLIFKRRRLRLTRRGLDAVPEAMRLMEHAAQAA---------------------------- +>tr|A0A0F9V682|A0A0F9V682_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0180300 PE=4 SV=1 +-------------------------------------------------FCSAAEAPSFREAASRLGTSPQTVTRAVQELEELlgePLFHRNTR-------QIHITGFGESMALQAREALATVDG------------------------------ +>tr|A0A0F9FD14|A0A0F9FD14_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_1967630 PE=4 SV=1 +---------------------------------------LSPIQYNLIRTLESVGPLTRKDLVKQLRTPRTTIYDNLAKLQKRKLLEKFSRNIGKRGRPLVI-------------------------------------------------- +>tr|A0A0B1TZ78|A0A0B1TZ78_9DELT Zinc uptake regulation protein ZUR OS=Desulfovibrio sp. TomC GN=NY78_1664 PE=3 SV=1 +----------------------------GKTMLTRAGIDPTPLRLAVAEVLAGEGrALPAGDILTLVrrqhQANKVTLYRILDLFVEKGLARRHSS--GDRALRYCLEPG----------------------------------------------- +>tr|A0A1F1JWU9|A0A1F1JWU9_9MICO Uncharacterized protein OS=Kytococcus sp. HMSC28H12 GN=HMPREF3099_09235 PE=4 SV=1 +----------------------------AEDALRAQGVRVTKPRREVLALLAAVAdLPTADEMLERLdpaaGATRATLYRTLQVGVEVGVVCHVHT--GHTPTRYHLSAP----------------------------------------------- +>tr|A0A1G1N809|A0A1G1N809_9BACT Uncharacterized protein OS=Omnitrophica WOR_2 bacterium RIFCSPHIGHO2_02_FULL_48_11 GN=A3D10_08780 PE=3 SV=1 +----------------------------VVELLARGQVASTVHRVGVLKVISRSPkAIAPRSLLQEIrkttPIDKVTLYRILDLFVAKKILRRMTG--QKGTMCYEVMCE----------------------------------------------- +>tr|A0A1I0BQX4|A0A1I0BQX4_NITER Fur family transcriptional regulator, ferric uptake regulator OS=Nitrosomonas europaea GN=SAMN05216309_11826 PE=3 SV=1 +----------------------------AEQLIQNAGKRSTPVRSAVLGVLLNAEdVLSHSEVLEHLqqlgAFDRVTVYRALDWLVTQGLVHKVAG--AGRAWRFQVTRS----------------------------------------------- +>tr|E7NWK1|E7NWK1_TREPH Transcriptional regulator, GntR family OS=Treponema phagedenis F0421 GN=HMPREF9554_02466 PE=4 SV=1 +--------------------------------------------------IPGGYNLKQEELAKALGVSRIPIRETLMTLESLGLVYRKA------TRHFFTVDFSAEEIIRIFQVAFNFELESIRNFNNEE-------------------- +>tr|A0A1N6G374|A0A1N6G374_9RHOB LysR family transcriptional regulator, regulator for metE and metH OS=Rhodovulum sp. ES.010 GN=SAMN05444722_0130 PE=4 SV=1 +---------------------------------------LELRHLRTIKAIHDAGGLARA--AERLNITQSALSHQVKGLEEQVGMELFV----RRTKPLRLSSAGLKLLRAAERVLPEIAALQAEFdgLKSGRSGRL---------------- +>tr|A0A225LZR3|A0A225LZR3_9BURK LysR family transcriptional regulator OS=Candidimonas nitroreducens GN=CEY11_22170 PE=4 SV=1 +---------------------------------------LEIRHLETLSAIRDTGSLQEA--AEHLHVTQSALSHQLRDLEVRLKTPLLN----RRTRPARLSTAGLRLVALADEILPRVKATERELqrLAAGRTGRL---------------- +>tr|Q2Y4V6|Q2Y4V6_9ARCH Putative uncharacterized protein C5_0050 OS=uncultured archaeon GN=C5_0050 PE=4 SV=1 +--------------------------------------------LDILKVTSeGEGRAKKTRIMQYAYLDWRNFQRHFGFLQENRFISDHNDPKEG--TSYYLTEKGIDLMGRLNAV------------------------------------ +>tr|A0A133VFN4|A0A133VFN4_9EURY Uncharacterized protein OS=candidate divison MSBL1 archaeon SCGC-AAA382A20 GN=AKJ51_05210 PE=4 SV=1 +--------------------------------------------SDILETVKNENDCKKTTIIRLANLDWDMASKYLNDLDKDGFLESFEDESKGN-EVFELSKKGKLLLKSLKKI------------------------------------ +>tr|A0A1F8P7I2|A0A1F8P7I2_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_50_9 GN=A2144_05980 PE=4 SV=1 +--------------------------------------------ADMLRVG--ESGAGKTEIMYSANMSFNQIQKYLDYLVNQGFIAKVSLDNTM--VAYQVTESGLKLLKAIDTL------------------------------------ +>tr|A0A0R2DFZ1|A0A0R2DFZ1_9LACO Transcriptional regulator (Transcriptional regulator, lysr family) OS=Lactobacillus rennini DSM 20253 GN=FC24_GL000302 PE=4 SV= +---------------------------------------MNLNQLRYFRVIVDEKQYTKA--ASKLFISQPSLSNSMKAFEEDLGGKLFN----KRGHQIELTKYGQLIYKTVCNTLDTLDQ------------------------------ +>tr|A0A1A9CK19|A0A1A9CK19_9ACTN Transcriptional regulator, ArsR family OS=Streptomyces sp. Ncost-T6T-1 GN=YW5DRAFT_03881 PE=4 SV=1 +----------------------------------------DPTRLQILRLIERSParEACVCDLTDCLGLRQPTVSHHLKVMTDAGILTRERR---GTWAWFSVDPEGLRRIRDILE------------------------------------- +>tr|A0A167FEY3|A0A167FEY3_9GAMM Uncharacterized protein OS=Pseudoalteromonas luteoviolacea H33 GN=N476_11225 PE=4 SV=1 +--------------------------------------KLNWDDFKVAHTVAKAGSLAKA--ATILKCNHTTVLRHINRLEDALNVTLFI----RHQRGYQLTDAGQIMSETLEDLNTQFIA------------------------------ +>tr|A0A1M5KDP9|A0A1M5KDP9_9RHOB DNA-binding transcriptional regulator, LysR family OS=Thalassobius maritimus GN=SAMN04488044_0933 PE=4 SV=1 +---------------------------------------FDWNDLRHLLAVHRTGSYSEA--GRRLGVSETTVSRRIAAIEAAlrvKLIQKRGSA------GYEMTDIGHLVLEHAEAIEQQSGK------------------------------ +>tr|A0A0F9HHQ0|A0A0F9HHQ0_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_2062450 PE=4 SV=1 +--------------------------------------------------IKYGDNLKIQKLAEKLCVSTMPVREALKRLQYERIVDIKPR---SCCSLRIPSKSEVIEIYELREVLELhAITKFRQNFDKSRLERLHEITESMRG------- +>tr|A0A149ZNP4|A0A149ZNP4_9NOCA Uncharacterized protein OS=Rhodococcus sp. LB1 GN=AZG88_17030 PE=4 SV=1 +---------------------------------------------TFIDALFREGPSSRAQIAKSTGISKPTISESAQRLLSTGLIVEVGQTATGMRGRS---------------------------------------------------- +>tr|A0A0X8JHH0|A0A0X8JHH0_9DELT Heavy metal resistance protein CzcA OS=Desulfovibrio fairfieldensis GN=AXF13_01455 PE=4 SV=1 +-EDAAFIREHPVQIANLLRSMGIKMLIHYTFLADMGTGRHEIHLCRFILSLARKnnsqsafpCHMTQQEVADLLGIHRATLARALQRLKQHGVISS---------------------------------------------------------------- +>tr|A0A1T4VPP6|A0A1T4VPP6_9DELT cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases OS=Desulfovibrio bizertensis DSM 18034 GN= +-LSEEFYRRNPEKAINLITTLAVKEAISYAYTTDVACADAMGRVCQSLLALVNEnqnqdvfsPDVTQSEIASMMGLHQTTVARAIKELRAKKIIGK---------------------------------------------------------------- +>tr|S2KKB6|S2KKB6_9GAMM Uncharacterized protein OS=Halomonas anticariensis FP35 = DSM 16096 GN=L861_09675 PE=4 SV=1 +------------------------------------GTDLTSHQMELLSRVLQHGGVLASPFGHAGEDSlLSRVLEDIGELESRGLITVKRFQDSQDPQQIELTAMGYAAL------------------------------------------ +>tr|K2QDH4|K2QDH4_9LACT Negative transcriptional regulator-copper transport operon OS=Lactococcus garvieae DCC43 GN=C426_1047 PE=4 SV=1 +---------------------------------NETEFNISNAELIVMRVIWSLGEARvdeiSCQISPDLDWSLATVKTLLGRLVKKGMLSTEKE---GRKFVYHPL------------------------------------------------- +>tr|U1HCQ4|U1HCQ4_9BRAD O-acetylhomoserine (Thiol)-lyase OS=Bradyrhizobium sp. DFCI-1 GN=C207_04181 PE=4 SV=1 +--------------------------------------------WSLLIIRDASLGRRrFGEFQASLGLAKNILATRLRTLVERDILKTVPASDGSAYQEYVLTPKGHGIFPILVALRQWTEEFDEHP------------------------- +>tr|A0A0D7Q9C9|A0A0D7Q9C9_9BRAD Transcriptional regulator OS=Bradyrhizobium sp. LTSPM299 GN=UP10_20280 PE=4 SV=1 +--------------------------------------------WSLLIVRDAFDGLRrFGDFQKNLGIAKGMLTTRLSKLLELDVLELVAASDGSAYQEYALTKKGRELFPIVVALRQWGEAHLYAR------------------------- +>tr|A0A193GBZ0|A0A193GBZ0_9BORD Transcriptional regulator OS=Bordetella flabilis GN=BAU07_07525 PE=4 SV=1 +--------------------------------------------WTLLILRDAFDGLKrFNAIQKSLGIPRNILTARLRLLVDRDILGVAPASDGSVYQEYVLTDKGRDLIPVISALRQWGEQHALAP------------------------- +>tr|U4T7R5|U4T7R5_9GAMM Transcriptional regulator, IclR family OS=Psychrobacter aquaticus CMS 56 GN=M917_0844 PE=4 SV=1 +--------------------------------------------LKVIKAMRSATfsGISVTELAKTIDTSAANICRDLDDLVSEGMAEKRDDG------RYQLSVAMLQIATAYQTDYNRMSSRL---------------------------- +>tr|L8DPL0|L8DPL0_9NOCA Transcriptional regulator, PadR family OS=Rhodococcus sp. AW25M09 GN=RHODMAR_3209 PE=4 SV=1 +-------------------------------------------RAAILLLLEDRPMHGyelIQQIAEKSNGtwkpSPGSIYPALSQLEDEGLVLIDKV---AGRKTAKLTEEGRTYVDDHRADLGSPWDDVADSVGVDARDLRALIGQLM--------- +>tr|A0A164LAT7|A0A164LAT7_9NOCA PadR family transcriptional regulator OS=Rhodococcus sp. EPR-147 GN=A2J02_03105 PE=4 SV=1 +-------------------------------------------RAAILLLLEERPMHGyelIQQIAEKSNGtwkpSPGSIYPALSQLEDEGLVLIDKV---AGRKTAALTDEGRTHIEAHRADLGSPWDDVAESVGVDARDLRALIGQLM--------- +>tr|A0A1J5K2V2|A0A1J5K2V2_9PROT Uncharacterized protein OS=Bacteriovorax sp. MedPE-SWde GN=BM556_16110 PE=4 SV=1 +------------------------------------------------SFVELSKTLNFSKAAKNLSMAQPGLSRQIRQLEESLQTSLFL----RDNKRVTLTQEGEYLRDHISPLLLGINDAV---------------------------- +>tr|S3V4F4|S3V4F4_9LEPT DNA-binding helix-turn-helix protein OS=Leptospira wolffii serovar Khorat str. Khorat-H2 GN=LEP1GSC061_1571 PE=4 SV=1 +----------------------------------------DPTRRSILERLSL-GPATVGELAEPFSMALPSFMQHLGVLEESSLVSSVKS---GRVRTYSLTHSTLDLGEEWFVKQRTVWER----------------------------- +>tr|A0A127F0D3|A0A127F0D3_9RHIZ ArsR family transcriptional regulator OS=Rhodoplanes sp. Z2-YC6860 GN=RHPLAN_46740 PE=4 SV=1 +----------------------------------------DPTRRAIVSRLCD-GPKSVSELSEPFELALPSLLKHLRALEQSGLISSEKI---GRVRTCRIEPRALHATEAWIRQHISAWEK----------------------------- +>tr|X8K4T5|X8K4T5_9FIRM FCD domain protein OS=Eubacterium sulci ATCC 35585 GN=HMPREF9092_1507 PE=4 SV=1 +-------------------------------------------QSAILRGEFEYGeLVSEKKLAEKLGVSRTPVREAMTRLSQDRLIKDTV----NGSIILGIQPKDLRDLIIIKQRIEPlIAVSLTENMTEKELNRLKDIVDQ---------- +>tr|A0A220U3V1|A0A220U3V1_9BACI Uncharacterized protein OS=Virgibacillus sp. LM2416 GN=CFK37_10250 PE=4 SV=1 +-------------------------------------------QNHLLENEFSPGeRLTESGLANMLGVSRGPIREAIRMLIHDGLLVQKG----VHIYVFDPTFDDVVDVYLCKERLEPlGAKLSAQNMSQADNEALMDIINR---------- +>tr|R7WIP2|R7WIP2_9NOCA GntR family transcriptional regulator OS=Rhodococcus rhodnii LMG 5362 GN=Rrhod_3564 PE=4 SV=1 +--------------------------------------------------------LSQVRLATELQVSRTPLREALRRLEAENLVVNQA----NRGVVVAPVALGDVEDSYAIRTLVEpsLLTATLETISQDDITAMSTALMRMKEA------ +>tr|R7WIQ2|R7WIQ2_9NOCA GntR family transcriptional regulator OS=Rhodococcus rhodnii LMG 5362 GN=Rrhod_3562 PE=4 SV=1 +--------------------------------------------------------MSQEQLAAEFEVSRTPLREALQRLEADGLLVAEA----NRGMHVAPIVNSETEESYALRLLVEppTVAAVIDHLTDADFAAMAKALEQMRRH------ +>tr|A0A0E3S1Y1|A0A0E3S1Y1_9EURY ATP-dependent DNA helicase OS=Methanosarcina lacustris Z-7289 GN=MSLAZ_0845 PE=4 SV=1 +--------------------------------------KLTETQKLMLRLVKESPYISIKEMSEIIGIRTSSIDKNIQTLKKKGLIKRVGPARGGHWEAIE--------------------------------------------------- +>tr|A0A0D2VZ17|A0A0D2VZ17_9PROT GntR family transcriptional regulator OS=Skermanella aerolata KACC 11604 GN=N826_11615 PE=4 SV=1 +---------------------------------------------------------PERDLEKQFGVSRNTLRKSLKLLQDKGRIVRHV----GRGSFVAPARQDLPqsrALDSFVPVSADSLVLRIHGASPAEIMEVRLVVE----------- +>tr|E8REJ2|E8REJ2_DESPD GntR domain protein OS=Desulfobulbus propionicus (strain ATCC 33891 / DSM 2032 / 1pr3) GN=Despr_1920 PE=4 SV=1 +---------------------------------------------------------PERKLAESLGVSRGSLRQAFHILAERGIIESRQ----GDGTYLLAPLGGGC----SA-EA-ILDAIGEQSGFVHDIIEFRQMIE----------- +>tr|A0A1R0YB10|A0A1R0YB10_9BACL Uncharacterized protein OS=Paenibacillus borealis GN=BSK56_22865 PE=4 SV=1 +---------------------------------------------------------TLQQLAADFSVSVTTVREALRILESQGNVSIEH----GRGMYVRNDPLLLD----DP-AV-ALEEL--ENISIVDLLEARLLIE----------- +>tr|A0A1Q9PBY0|A0A1Q9PBY0_9ARCH HTH-type transcriptional regulator OS=Candidatus Heimdallarchaeota archaeon AB_125 GN=HeimAB125_15210 PE=4 SV=1 +---------------------------------------------KILTLLGNMK-LTADELTKELGISRPAVEKHLKQMLEIGLIERKADTYPTLKYIYTIPSPGLELLSNVRDSIDTFISSLREEYT----------------------- +>tr|W6WCP5|W6WCP5_9BURK Transcriptional regulator, LysR family OS=Burkholderia sp. BT03 GN=PMI06_008851 PE=4 SV=1 +--------------------------------------AIELRQLRYFSILARELHFGRA--ADLASITQSALSQQVAKLEELVGAQLL----NRDRRGVTLTASGEALRNSADAIFAQVERGL---------------------------- +>tr|A0A0Q0XIM7|A0A0Q0XIM7_9FLAO ArsR family transcriptional regulator OS=Flagellimonas sp. DK169 GN=AAY42_13630 PE=4 SV=1 +-----------------------------------------------------NDGVCVGYIQDKTGLSQSTISTYLNSMQNANLVIPTRH---GKWTYYKRNEEVIEAYVESLK------------------------------------- +>tr|A0A163Y443|A0A163Y443_9FLAO ArsR family transcriptional regulator OS=Myroides marinus GN=AV926_00925 PE=4 SV=1 +-----------------------------------------------------DYGVCMSVIQKKAGLSQSTTSAYLTNMVNIGLLTSVRN---GQWTYYKRNEDKIAELAHYIQ------------------------------------- +>tr|A0A1Y2PBJ5|A0A1Y2PBJ5_9FLAO ArsR family transcriptional regulator OS=Tenacibaculum holothuriorum GN=WH52_10400 PE=4 SV=1 +-----------------------------------------------------DFGVCGTFIQKKTEMSQSTISTYLNNMEKCELLISTRK---GKWTYFKRNEKTIEDYIEYLK------------------------------------- +>tr|A0A133VNG9|A0A133VNG9_9EURY Uncharacterized protein OS=candidate divison MSBL1 archaeon SCGC-AAA382N08 GN=AKJ56_02010 PE=4 SV=1 +-----------------------------------EKLGFTERQYQILNHVQDNGETLSKEVAKKLDIDIHNASMRLKDYYENGWLSRERGA--YGRFKYTITEQGENRIDWLEE------------------------------------- +>tr|M1E6M1|M1E6M1_9FIRM Segregation and condensation protein B OS=Thermodesulfobium narugense DSM 14796 GN=Thena_1242 PE=3 SV=1 +---------------------------------SEKDnKRLSKSMLEVLAIIAYNQPISASGVSKIRG---LRSEKQVMKLFENGFIKILSF---NNApikqPLFGVSTK----------------------------------------------- +>tr|A0A0Q4BC52|A0A0Q4BC52_9EURY Uncharacterized protein OS=Methanomassiliicoccales archaeon RumEn M2 GN=AOA81_01875 PE=4 SV=1 +---------------------------------KFSDMEIPPATMRTLSTIAYNQPVLQSELFRARG---VRTYEDVRELMSMGFVAGRKT---GQTLELTTTKR----------------------------------------------- +>tr|A0A069K2J1|A0A069K2J1_9ACTN LysR family transcriptional regulator OS=Streptomyces sp. NTK 937 GN=DT87_29480 PE=4 SV=1 +--------------------------------------------------------------AERLGVSPGRVSQSIKKQERRigaPLFVRTTR-------TVRLSPLGEQLYQALKSGHRQITQGI---------------------------- +>tr|E2SQM6|E2SQM6_9FIRM Transcriptional regulator, GntR family OS=Erysipelotrichaceae bacterium 3_1_53 GN=HMPREF0983_03545 PE=4 SV=1 +---------------------------------------------------------SVRAMASQIGVNPNTVAKAYQELEEQGYIYSEK----GKGCFVADNESDKLIREDKLKDFKGTVADMKQhHIEREELYKAID-------------- +>tr|W7CT63|W7CT63_9LIST GntR family transcriptional regulator OS=Brochothrix campestris FSL F6-1037 GN=BCAMP_08280 PE=4 SV=1 +---------------------------------------------------------SIREYASMVGINPNTVSKAYQELERQHVILTIK----GKGAFVADKQNAVksiVDTQLSKQTLEATLLDFIYqGIDAEILKQWVD-------------- +>tr|A0A173XZS7|A0A173XZS7_9CLOT Uncharacterized protein OS=Clostridium paraputrificum GN=CP373A1_10020 PE=4 SV=1 +---------------------------------------------------------SVRKLSQELNVSTITIKRAYLELEKAGITYSVS----GVGTFVRVKDNEElinENKEKLFCELDDIVGKLLDgKCTKEEIIKRVN-------------- +>tr|A0A1J0A4K9|A0A1J0A4K9_9ENTE PadR family transcriptional regulator OS=Vagococcus teuberi GN=BHY08_02960 PE=4 SV=1 +-------------------------------------------ELCVLYLLKNKDrygyELTQK-MNEHIVITEGALYPILRRLVKEEYCSTYlkESSSGPARKYYSLTDKGRQHLEKLFSEWNLFVESVQSLCQEED-------------------- +>tr|A0A1L8ZKN5|A0A1L8ZKN5_9BACI PadR family transcriptional regulator OS=Bacillus obstructivus GN=BLX88_13375 PE=4 SV=1 +-------------------------------------------ELCVLILISKKDqygyELAQN-ISSKIEVAEGTLYPLLRRLTKDDLLTTYllESTEGPPRKYYSITTKGLEYMFDLISQWRQFSEAVNQFITEGM-------------------- +>tr|A0A160T459|A0A160T459_9CHLR HTH-type transcriptional regulator OS=Candidatus Promineofilum breve GN=CFX0092_A1597 PE=3 SV=2 +--------------------------------------GFSEVMGHLYGTLLLSPqPLSLDDLGDTLEISKGSVSMNMRDLERWGMAKEVWVRGERRKFY----------------------------------------------------- +>tr|A0A1S2W9E1|A0A1S2W9E1_9BACL Uncharacterized protein OS=Exiguobacterium sp. KRL4 GN=BLD48_05840 PE=4 SV=1 +--------------------------------------KLTKRQREVLYWRYEVD-LSQEMVSEISAVRQQSVDDVENAAFRD--------------------------------------------------------------------- +>tr|A0A1B7XPK4|A0A1B7XPK4_9FLAO Transcriptional regulator OS=Tamlana sp. s12 GN=VQ01_01055 PE=4 SV=1 +--------------------------------------QLAPVAARIFAYIVLTGksGTTFDNLVQVLCASKSTISTNLNHLQDLKKIEYFTKTGDRKKYFKVNDNSILQKIDEMIFNWTE--------------------------------- +>tr|H8I689|H8I689_METCZ Putative transcriptional regulator (IclR helix-turn-helix domain) OS=Methanocella conradii (strain DSM 24694 / JCM 17849 / CGMC +---------------------------------------LSGKYSDILELIDFRE-MSVSDISQALKINPGSAHYRLKELQRRGLVKMVREETKGNVVKKYYRAAARNIYLDGSKFK--ALRPGEASPMDGFYDRLIALLA----------- +>tr|Q0W5D1|Q0W5D1_METAR Uncharacterized protein OS=Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50) GN=RCIX1094 PE=4 SV=1 +---------------------------------------CSPRYAEIIRIISGEE-FSVSDVARKLGANSGSVYYHMKELEKHGLVKLVREEIVGGVVKKYYRKAAMNFTFNISDPSSpSAAAAVAAGINEEFWEKLIKSLS----------- +>tr|A0A0J7Z976|A0A0J7Z976_9ACTN Uncharacterized protein OS=Streptomyces regensis GN=ACZ91_65045 PE=4 SV=1 +--------------------------------------------------ITPGTHLVEDTVAESFDVSRGPVRDALRMLRLENLVEPQR----RGVHVVGLSTTDVRELYAIRQAIEGlAVTTAIGLGEHRSGAGMAQALRGMADTATPTHA +>tr|A0A1B3NF70|A0A1B3NF70_9BRAD Uncharacterized protein OS=Bosea sp. RAC05 GN=BSY19_3933 PE=4 SV=1 +--------------------------------------------------FRNGERLNERHLAEMLGVSTTPVKDAIRKLESEGLVRTEAR---RGVFVEF-SARQALEMALGRAALESvMTHIAANRLGDADITEIGRLIEEMAHATQHSAL +>tr|I7FFX7|I7FFX7_MYCS2 GntR family transcriptional regulator OS=Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) GN=MSMEI_3867 PE=4 SV=1 +--------------------------------------------------FPAEGRMSVVSIAEQLKMSRSPVRAAVERLVTEGLLVVTA----VGIELAQLDHVDLIDGLRVRSRLEGlAARLTTDRLTDADLDRLRENLTQFDTAVRGGDT +>tr|A0A0G1ICS2|A0A0G1ICS2_9BACT Regulatory protein ArsR OS=Parcubacteria group bacterium GW2011_GWE1_43_8 GN=UW06_C0047G0006 PE=4 SV=1 +--------------------------------------------LEILLLLNRQAPLPLYQIAAKVRLSVKSTNKHLSQLLHTGFVAKNRQ---GLFVLYRLEDEAKPLVTKLLKLL----------------------------------- +>tr|A0A0G1LJI3|A0A0G1LJI3_9BACT ArsR family transcriptional regulator OS=Candidatus Giovannonibacteria bacterium GW2011_GWA1_44_25 GN=UW53_C0004G0001 PE=4 SV=1 +--------------------------------------------LKIMKLLFGCGEFTVTDISKEIGLSLKATSKHVIAMDNLGFVKNTGK---KGHVYYSIDLSQHTKVKELLKMI----------------------------------- +>tr|A0A0G1MYL7|A0A0G1MYL7_9BACT ArsR family transcriptional regulator OS=Parcubacteria group bacterium GW2011_GWC2_45_7 GN=UX17_C0020G0006 PE=4 SV=1 +--------------------------------------------LAILKAIVKHDELSVKMICQKLDKGVKLVSKHLGILAYMNIVEGQGK---LGSVWYKLHPSLRLEVKTIIHKF----------------------------------- +>tr|A0A0G1CB68|A0A0G1CB68_9BACT Transcriptional regulator, ArsR family OS=Parcubacteria group bacterium GW2011_GWD2_43_10 GN=UV57_C0027G0013 PE=4 SV=1 +--------------------------------------------LAIAVHLKRHHEATVGQLAALLKVSFPTASKHLSILAAADVVEYERR---SKEVYYYLADDIPAVASAILKYC----------------------------------- +>tr|A0A1G2L542|A0A1G2L542_9BACT Uncharacterized protein OS=Candidatus Sungbacteria bacterium RIFCSPLOWO2_01_FULL_47_10 GN=A2934_03795 PE=4 SV=1 +--------------------------------------------IAIIRYLKKEESAPVGEIASAIHLSFRSTSRHLRVLASSGILESEQK---GLTIRYGISSARGRIINTIISLL----------------------------------- +>tr|A0A1G2V4H6|A0A1G2V4H6_9BACT Uncharacterized protein OS=Candidatus Zambryskibacteria bacterium RIFOXYC1_FULL_39_10 GN=A2431_04320 PE=4 SV=1 +--------------------------------------------ILMLKILKKRNKISMGNMASQIKLSFRSTSKHFSILYTVGIVDREQH---GLTMYYSLSSKPSSIISQILSII----------------------------------- +>tr|A0A1G2D3D9|A0A1G2D3D9_9BACT Uncharacterized protein OS=Candidatus Lloydbacteria bacterium RIFCSPHIGHO2_02_FULL_50_13 GN=A3D65_03430 PE=4 SV=1 +--------------------------------------------LQIIRFLLKNKGMSVGEIAEEIETSLKSTSKHLLTLYHAEFLEKDRV---HGLTLYNLSGNLGDVERMAVNSI----------------------------------- +>tr|L8DBW1|L8DBW1_9NOCA Transcriptional regulator, AsnC family OS=Rhodococcus sp. AW25M09 GN=RHODMAR_1077 PE=4 SV=1 +--------------------------------------NIDRLDIELLGALSRNARMGIMELASTLGVARNTVQARLSRMIEEHYLAGFRPDIDLAEVGIAVQA------------------------------------------------ +>tr|A0A060HND0|A0A060HND0_9ARCH Putative transcriptional regulator, AsnC family OS=Nitrososphaera viennensis EN76 GN=NVIE_005260 PE=4 SV=1 +--------------------------------------DIDELDIRLVEILQKDSSTPSVKIAGMLRVTEGTVRNRVNKLRRLGVIRRFTISIDPMAMGQGAIA------------------------------------------------ +>tr|A0A1B1ZV97|A0A1B1ZV97_9PSEU AsnC family transcriptional regulator OS=Pseudonocardia sp. HH130630-07 GN=AFB00_01045 PE=4 SV=1 +--------------------------------------SLDALDVDLLAALRERPRAGALELSRVLTVARGTVQARLDRMERAGVITGYGPDVDLPAAGYGVQA------------------------------------------------ +>tr|A0A1S1NR53|A0A1S1NR53_9MYCO AsnC family transcriptional regulator OS=Mycobacterium sp. NE-TNMC-100812 GN=BKN37_00415 PE=4 SV=1 +--------------------------------------PIDSIDARILLLLFEHPRATTIAIADRAGISRNTAQSRIARLEASGALDSFERRVTPEALGYPLTA------------------------------------------------ +>tr|A0A0M0BN11|A0A0M0BN11_9ARCH Uncharacterized protein OS=miscellaneous Crenarchaeota group-15 archaeon DG-45 GN=AC482_05450 PE=4 SV=1 +--------------------------------------------LDILGIIGG-GTSKPTCIMYGANVSWEILQQTLAAMVSRGLVREIDARdarrRDRRtKTRYEITQKGEDIIRHFRRARG---------------------------------- +>tr|A0A1F5DM85|A0A1F5DM85_9ARCH Uncharacterized protein OS=Candidatus Bathyarchaeota archaeon RBG_13_52_12 GN=A3K78_06230 PE=4 SV=1 +--------------------------------------------QEILTHVHN-GNYLPTRLMHKTHISWVAFNRIKEPLISQGLLEEVED-pGDRRsRIKYRATEKGEKFLEYFGTAMK---------------------------------- +>tr|N9CUH4|N9CUH4_ACIJO Uncharacterized protein OS=Acinetobacter johnsonii ANC 3681 GN=F946_01379 PE=4 SV=1 +--------------------------------------------------LSKRGKTSVVDVQGMMGMTTRTVQRYLDQLVQAGYVLRD----DATPAGFIPSEKAKQLF------------------------------------------ +>tr|R5LU83|R5LU83_9SPIR D binding transcriptional repressor OS=Brachyspira sp. CAG:700 GN=BN758_01737 PE=4 SV=1 +---------------------------------------------NIIEFVYKNKNVTLDQICDNFNISKSTVRRDLSEILKDSNLQKTYGG------------------------------------------------------------ +>tr|A0A1Q2D7C8|A0A1Q2D7C8_9ENTE DeoR family transcriptional regulator OS=Vagococcus penaei GN=BW732_08495 PE=4 SV=1 +---------------------------------------------LMKHYILDRHFVSLKELERHFNVSMNTVRRDINQIIEDARFQKVYGG------------------------------------------------------------ +>tr|K2ER19|K2ER19_9ZZZZ ATP-dependent DNA helicase RecG OS=groundwater metagenome GN=ACD_21C00261G0003 PE=4 SV=1 +------------------------------------GEGSEISSEKILKCISKDKYISSKKISEAIGISPRAVEKQIAKLKSLGYLKRIGS---PKAGYWGIVTNRTKKNDK---------------------------------------- +>tr|X1JES4|X1JES4_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S03H2_50807 PE=4 SV=1 +------------------------------------NEGVKFRLKKEISYLNTYKSIRRPNVERLFNISTATAERDLSILKRLNLIIFEGA---PKTGRYILTNKGKKILDS---------------------------------------- +>tr|D3EJ54|D3EJ54_GEOS4 ROK family protein OS=Geobacillus sp. (strain Y412MC10) GN=GYMC10_6270 PE=4 SV=1 +----------------------------------------SINQQKVLFLIYSEGPISRVELAEKTGLSRQTVTNIVNRLLKEKIiVTGELIdlEAGSGRKRVGLHINSGHFYAIGLELAGKYIRGKVFNLRQEAVASAERTSNK---------- +>tr|A7NGL7|A7NGL7_ROSCS ROK family protein OS=Roseiflexus castenholzii (strain DSM 13941 / HLO8) GN=Rcas_0477 PE=4 SV=1 +----------------------------------------NHNSRLVLRIIYEDEAISRADIARKTGLTRTTVSTVVGELIEQGLiEETGAGQSSGGRLPILLRVAHEAHSVLALSFEDTQIVGALVDMRGSIQRRVSLSLYG---------- +>tr|X0VS60|X0VS60_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=S01H1_54145 PE=4 SV=1 +---------------------------------------------DLLVSLKPKDNLSIHRLSRETDITYTHLHRMLTEFERLGWITTYIE---GREKRIELTDTGKEMKNHALPIIIEL-------------------------------- +>tr|W1I3X7|W1I3X7_9BACT Uncultured bacterium plasmid pRGI01058 OS=uncultured bacterium PE=4 SV=1 +---------------------------------------LDSKQVDVLIFILENTKSsdntfigTYRKISEGANVALETVRKVMHKLQRqndqngIPFIKRIQNG------------------------------------------------------------ +>tr|A8MA70|A8MA70_CALMQ Transcriptional regulator, TrmB OS=Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167) GN=Cmaq_0152 +-------------------------------------IGLSKYQLRVYLTLVERGPLTAGLIAKYADVPSSKVYSVLKSMVRLGLIDVDSG---KRPEVFVAKP------------------------------------------------ +>tr|A0A1J5KGN8|A0A1J5KGN8_9FLAO PadR family transcriptional regulator OS=Flavobacterium sp. MedPE-SWcel GN=BM557_07405 PE=4 SV=1 +--------------------------------------------------------------KGKIDISEGALYPILHKMEADKILETEKIYIGKRvRKYYQITQSGKKVALEITNELNDFISTLSLIFNDK--------------------- +>tr|A0A1C7GSP3|A0A1C7GSP3_9FIRM Uncharacterized protein OS=Ruminiclostridium sp. KB18 GN=A4V00_16940 PE=4 SV=1 +--------------------------------------------------------------EGKLRLIENSLYGTVYRLQREGYISSKKEENVARaRVFYHLEPSGEVYLAKLIKEYESISEGIRLVIGNP--------------------- +>tr|A0A0K3B3M0|A0A0K3B3M0_9PSEU Transcriptional regulator, HxlR family OS=Kibdelosporangium sp. MJ126-NF4 PE=4 SV=1 +----------------------------------------------VMLVLREalLGTTRFEQFRTILEVADNVLSRRLTDMVDAGLLRRSRYQGKQRaHDEYVITEAGADLLPVLDALA----------------------------------- +>tr|M0NFF8|M0NFF8_9EURY Uncharacterized protein OS=Halococcus thailandensis JCM 13552 GN=C451_01743 PE=4 SV=1 +--------------------------------------------GEILWAINDQP-RTKPALTEALDTSRSTINRGVDELEEAGCIERRDS-------KYYTTLLGELSCTRYRNYRSNMSA------------------------------ +>tr|R8CLC5|R8CLC5_BACCE Uncharacterized protein OS=Bacillus cereus HuA2-9 GN=IG9_05494 PE=4 SV=1 +-----------------------------------------------------------------YKSSFGSLYPALKRLEEKEWVSVKNVKGDSKnKKNYTIQNAGKVALFKWLEQPLQTTKnehlvkiFFIDYLEKDKrSNLLKEFYYHLKNQKSKLQQ +>tr|A0A0W8E581|A0A0W8E581_9ZZZZ Transcriptional regulator, padr family OS=hydrocarbon metagenome GN=ASZ90_018770 PE=4 SV=1 +-----------------------------------------------------------------YNASYGSIYPILKKQEEAGLVSVEELVEGGRfKKIYQLTEKGRNTFLQWLEEPPQPITikndmlvrlFFFNNVTREKqVEITEIYLDHLKDFRQRLDD +>tr|A0A1D9P0N0|A0A1D9P0N0_9FIRM PadR family transcriptional regulator OS=Butyrivibrio hungatei GN=bhn_I1007 PE=4 SV=1 +-----------------------------------------------------------------WKGSFGSIYPALGEMEKQELVKRKKSdKSSGReKIVYQITKDGKETLKAWLNDEKAINDlkyetllkmYFGGIQDRSVtIRNIEIFEQQVKENLEVLKF +>tr|A0A1F6PTI5|A0A1F6PTI5_9BACT Uncharacterized protein OS=Candidatus Melainabacteria bacterium GWA2_34_9 GN=A2039_01995 PE=4 SV=1 +-----------------------------------------------------------------LSASFGSIHPAMKKLEKNGYISAKRKmSSGGQkSSTYSITIEGKEHFKKLMTSEINESPtysnqlinikmMLLDLLDENLrKNTINLIKKYYEIHLltarELLET +>tr|A0A1W1H9H9|A0A1W1H9H9_9DELT Transcriptional regulator (PadR family protein) OS=Desulfamplus magnetovallimortis GN=MTBBW1_1680008 PE=4 SV=1 +-----------------------------------------------------------------FNTGFSSIYPKLKKLEKEERVRVSQVIKNGKlNKLYTLTDEGKKAFLEWLEIKPEIGRirdeallkvFFFDHLEDDKiVPQLKGYVGDLSQHVQNLLS +>tr|A0A1N6Z7U2|A0A1N6Z7U2_9BACI Transcriptional regulator, IclR family OS=Bacillus simplex GN=SAMN05878482_10366 PE=4 SV=1 +--------------------------------------------LDVLSYFTAETpEWGLRDLARKMEMNHTVLHRILKTYENKGYLIQNESTK----------------------------------------------------------- +>tr|D3ADZ4|D3ADZ4_9CLOT UbiC transcription regulator-associated domain protein OS=Hungatella hathewayi DSM 13479 GN=CLOSTHATH_01823 PE=4 SV=1 +---------------------------------------------------------AEMEFCEFCSVSRPTVRQALSELVSEGYLTRLK----GKGTYVSRPKIQAMFFNRLLSFNEEMKER----------------------------- +>tr|D1AQI9|D1AQI9_SEBTE Transcriptional regulator, GntR family OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_3410 PE=4 SV=1 +---------------------------------------------------------KELDLCKIYNVSRPTIRKAMDILVQNGNLIRIK----GKGTYVSSdKKIKQEFTHIIQNFNAEMSQK----------------------------- +>tr|A0B595|A0B595_METTP Transcriptional regulator, PadR family OS=Methanosaeta thermophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) GN=Mthe_006 +-------------------------------------------DILILSILGERPMCGydlIKEIYRRYNVllSQGAVYPILYSMVDDGILRSEYSRGNMRTKIYTLTPKGQEVMRRKIGKMVYALEYMLSFLKGSCSE------------------ +>tr|A0A0Q9IGA4|A0A0Q9IGA4_9BRAD Uncharacterized protein OS=Bosea sp. Root381 GN=ASE63_20065 PE=4 SV=1 +--------------------------------------------------LRPGDRINENQLSIELDVSRSLIRQALRSGELSHLVEIVHN---KGAFVRKPDLTTIFDLYDVRAGLAYTAGKILArRATMEQIAELYALYEEMEARREAKDP +>tr|A0A1H5SMV5|A0A1H5SMV5_9EURY Winged helix-turn-helix DNA-binding OS=Halobellus limi GN=SAMN04488133_0019 PE=4 SV=1 +--------------------LRRRYEDAATTVFMEAASKLTTAVHDILATVVQENGATYDKLEEVTGLARSTVRYHVARLAEKGVLKRIGNP------------------------------------------------------------ +>tr|A0A0N0BNQ5|A0A0N0BNQ5_9EURY Uncharacterized protein OS=Haloarcula rubripromontorii GN=AMS69_10250 PE=4 SV=1 +--------------------MEEANEERERKILKTTYESLSAAKWDILWTVAVTEGCSYETLEEITGFSYDYVREVVQELESMDILLRVTYP------------------------------------------------------------ +>tr|K7QZ58|K7QZ58_THEOS Transcriptional regulator OS=Thermus oshimai JL-2 GN=Theos_2421 PE=4 SV=1 +--------------------------------------------LLILRALHERGqATAGELRALFGGRSLRSVYDLLRVLEEAGLVVRLARR-KGWTLAYPHPFFTAQQ---E--------------------------------------- +>tr|A0A0C2RK62|A0A0C2RK62_MICLU Uncharacterized protein OS=Micrococcus luteus GN=OC70_07895 PE=4 SV=1 +--------------------------------------------FALLDVVATDSrGMTAKEIAAALQMPLPTVYRMLKTLVASGHVVHLREE-SRYGLGYKLHALDTSLRRQV--------------------------------------- +>tr|A0A1F1W937|A0A1F1W937_9MICO Transcriptional regulator, IclR family protein OS=Brachybacterium sp. HMSC06H03 GN=HMPREF3159_14245 PE=4 SV=1 +--------------------------------------------IAVLEAVAEHGSSTARRISEATSIPLPTVYRIAQELIRSEYLVHLRTE-KRFALGYKLHRLAVGLHDDL--------------------------------------- +>tr|A0A1J4N913|A0A1J4N913_9ACTN Uncharacterized protein OS=Nocardioides luteus GN=UG56_004695 PE=4 SV=1 +--------------------------------------------ANTLAIISENPaGVSAKVLARRLEQSLSTTYYALQTLTDVGMIEHSPTTSGLYTLGPQIAALYRGYVANR--------------------------------------- +>tr|A0A1M5EPV2|A0A1M5EPV2_STRHI Transcriptional regulator, IclR family OS=Streptoalloteichus hindustanus GN=SAMN05444320_10578 PE=4 SV=1 +--------------------------------------------MDVLEAVAAADePISAKALARAVGCGLSTVYNLIAVLTGRGYLART--S-AGYVLGHQVSGLNRAFSRQM--------------------------------------- +>tr|E1QRL2|E1QRL2_VULDI Transcriptional regulator, ArsR family OS=Vulcanisaeta distributa (strain DSM 14429 / JCM 11212 / NBRC 100878 / IC-017) GN=Vdis +----------------------------------------NNVRISIMDMLSR-GPMTVTSLAQELGMLKGVVHRHVKALEDFGWIRQLSN---DEVKVMGLSREANRIY------------------------------------------ +>tr|A0A1X1W7N2|A0A1X1W7N2_9MYCO Transcriptional regulator OS=Mycobacterium iranicum GN=AWC12_27785 PE=4 SV=1 +----------------------------------LATWRLPRSTGRVYGYLLLRGdASSTEELCSRLHLSAGAVSTATRELVSWGLARTLPQAGSRRL------------------------------------------------------- +>tr|A0A0B8NEW1|A0A0B8NEW1_9NOCA Uncharacterized protein OS=Nocardia seriolae GN=NS07_v2contig00147-0010 PE=4 SV=1 +--------------------------------------------LRVIWELEP-GPLGFLELRRRMgNCSSSMLSVRLQRLTETGVVTKNADK------SYELTTVGKQLGLALESVWQ---------------------------------- +>tr|A0A1U9YWF4|A0A1U9YWF4_9RHIZ Cyn operon transcriptional activator OS=Martelella mediterranea DSM 17316 GN=cynR_5 PE=4 SV=1 +---------------------------------------HDIWRFQHFLGVVDAGSFHGA--ARAMNISQPALTKSIRLLEEAfgtELFLRLPR-------GVRLTEAGEMMHIRAREVEAAWNAAI---------------------------- +>tr|A0A1Y5TSP2|A0A1Y5TSP2_9PROT HTH-type transcriptional regulator CynR OS=Oceanibacterium hippocampi GN=cynR_4 PE=4 SV=1 +---------------------------------------IGLRKLRHVVETARFESVTRA--ADALLITQSALTRSIAEVEAElgiQLFVRLPR-------GVRTTEAGRSFVEKALRIIGDVNSLV---------------------------- +>tr|G0A909|G0A909_COLFT Transcriptional regulator, ArsR family OS=Collimonas fungivorans (strain Ter331) GN=ydfF PE=4 SV=1 +-----------------------------------------PTRIQMLALLMEGRALTAKELAYGTDIKPATATAHLRQLVDDKLLDMTSQ---GRHKYFRLASP----------------------------------------------- +>tr|A0A0R1UZM1|A0A0R1UZM1_9LACO Transcriptional regulator, ArsR family OS=Lactobacillus satsumensis DSM 16230 = JCM 12392 GN=FD50_GL000674 PE=4 SV=1 +----------------------------------------NAQRTKILLFLLDNRFHTVNEITQKTDLKNNTVSFHLGKFLKAAWVICTVK---GKFHYYRLKNA----------------------------------------------- +>tr|A0A1B9L878|A0A1B9L878_9GAMM Uncharacterized protein OS=Gilliamella apicola GN=A9G11_09570 PE=4 SV=1 +----------------------------------------DANRVMIISELMNGRSLCASWLAKQLNLSPSATRFHLKKLEDAQLIHQRTC---GKHHYYEIKNQ----------------------------------------------- +>tr|G5HLP2|G5HLP2_9FIRM Uncharacterized protein OS=[Clostridium] citroniae WAL-17108 GN=HMPREF9469_03504 PE=4 SV=1 +--------------------------------------------FKILEVLAKnPEGLSLLALSEQTGLPSSTVHRLLHTLFALGYTEWRSSNSSPYKLTLRLFEYGCYSVenRTFIQKAHPFIKRLSEEL------------------------ +>tr|A0A1V5VBB0|A0A1V5VBB0_9BACT Acetate operon repressor OS=Lentisphaerae bacterium ADurb.Bin242 GN=iclR_1 PE=4 SV=1 +--------------------------------------------FQILEMLYEnknpDDGLGIASVSRELGLKLPTVHNLMKTLVLLGYAEQK--EDGKYRPGPKADKFGMKSDSRLLALARPLIARLVREL------------------------ +>tr|A0A081P7L1|A0A081P7L1_9BACL Uncharacterized protein OS=Paenibacillus tyrfis GN=ET33_33135 PE=4 SV=1 +---------------------------------------------RLHQVMKENPRASQRELAKILGCSPAWVSKLIRGLQMDRAKHHikGVLDDD---------------------------------------------------------- +>tr|A0A151F6Q4|A0A151F6Q4_9EURY Uncharacterized protein OS=Thermoplasmatales archaeon DG-70 GN=AYK18_02400 PE=4 SV=1 +----------------------------------------HAHRLRILVLLLN-GPQELSHLLDAVKISKTALANHLTHMMDKGVIERSERG------TYQITADGKDLITAVATFYEQSTARELN-------------------------- +>tr|A0A1Q3YMG3|A0A1Q3YMG3_9BURK Uncharacterized protein OS=Burkholderiales bacterium 70-64 GN=BGO72_13875 PE=4 SV=1 +--------------------------------------------LALLEAFDrETPALGVTQLAAKVGLHKSTAYRLATTLAGEGFLHQDRA-TGRYSLGGRFYRIAAGFVEQD--------------------------------------- +>tr|A0A1M6CS92|A0A1M6CS92_9ACTN DNA-binding transcriptional regulator, IclR family OS=Nocardiopsis flavescens GN=SAMN05421803_101797 PE=4 SV=1 +--------------------------------------------LQIIFAVAeaEGPDMGVSELARSLNLSKTVVHRVVRTLVDDGFFQMDER-TRRYRLGPAAVSVGLSALARM--------------------------------------- +>tr|A0A0Q4FLJ7|A0A0Q4FLJ7_9FLAO Uncharacterized protein OS=Chryseobacterium sp. Leaf201 GN=ASE55_00770 PE=4 SV=1 +--------------------------------------------FSILLELHYHEKLRFKDFFEVLkGISPKVLSSELSLLEVHRLIQKNIEYTpTQDITYYALTEHAQEIWTVLNTLID---------------------------------- +>tr|A0A1Q6A6J9|A0A1Q6A6J9_9SPHI Uncharacterized protein OS=Mucilaginibacter polytrichastri GN=RG47T_5118 PE=4 SV=1 +--------------------------------------------IMIIASLSVFGEKRYTELQRIIdGIGTKMLSKELQELEINGLIKRTVMPTKPVTVKYELTAYGSTLKPIIDEMAS---------------------------------- +>tr|A0A1M4T3G9|A0A1M4T3G9_9SPHI Transcriptional regulator, HxlR family OS=Pedobacter caeni GN=SAMN04488522_10169 PE=4 SV=1 +--------------------------------------------MYVIIAIYNG-NHRYREIARSIsGITFAMLSRELESMALNKLIIRTEDPDFSKDVKYTLSAYCQSIYPLVESLID---------------------------------- +>tr|A0A061NW37|A0A061NW37_9BACL Transcriptional regulator, GntR family OS=Geomicrobium sp. JCM 19038 GN=JCM19038_2036 PE=4 SV=1 +--------------------------------------------------LTPGEKLSFRKVAHNYNVSMMPVREAMTRLHVQDLITINK----KTIRIKKLTASEVEDIFQMRFKLEAmAVEKAMFNIGDQEKDELLNTIAAM--------- +>tr|A0A1Q3SPM4|A0A1Q3SPM4_9CHLR Uncharacterized protein OS=Chloroflexi bacterium 54-19 GN=BGO39_14165 PE=4 SV=1 +----------------------------------------------IVLAGKTPRRLSDIAIAAELRISRTPVRQALDRLAQEGLVHFDPR---RGFWTHVYTAEDVEEIYQIREATEVlALRLAAPRLKQAELENHLKTLLDIRATLPNPH- +>tr|A0A1Q5B2K2|A0A1Q5B2K2_9ACTN Uncharacterized protein OS=Micromonospora sp. CB01531 GN=A6A27_24520 PE=4 SV=1 +----------------------------------------------LAGELAPGTLYSVVELSNQLGVSRTPVREALLQLASNGMVRFERS---KGVRILELSTQDIEEIYMLRIFLEApAAYRAAQHMPQEHREAFQSAFAGMRAACEAGN- +>tr|A0A1Q4UQY2|A0A1Q4UQY2_9PROT GntR family transcriptional regulator OS=Thalassospira sp. TSL5-1 GN=LF95_15115 PE=4 SV=1 +----------------------------------------------REGRLAPGQRLTEAEFTRKLAVSRPTIREAFRQLCNDGLLQFEPH---RGASVRQLTRHELDDLFVIRASLEAlAVRLSAPLLEQApgPLLQIQASLDKAEQEGDRKK- +>tr|A0A1P9Y2H5|A0A1P9Y2H5_9BURK Uncharacterized protein OS=Burkholderia sp. KK1 GN=A9R05_21780 PE=4 SV=1 +----------------------------------------------RLGQFAGGHRLIEGDLAAELDVGRGSVREALRILAGDGVIELVPH---KGASVRRLNQGELIQIFEALTATHWeAVRICARRFEE-peIQQSISASLKRVEQVRRAEE- +>tr|A0A1V2ALY5|A0A1V2ALY5_RHIRD GntR family transcriptional regulator OS=Rhizobium radiobacter GN=BV900_11275 PE=4 SV=1 +----------------------------------------------VSGRLHGGERLLPNELAADLGISPTPVKEACLKLEADGLVVNSSR---RGMVVRDFTVEDVEELYAARMLLEKgAVEVAFDAGQLDeaLHAQLLESLAKHREFAKSaTL- +>tr|A0A089HVL7|A0A089HVL7_PAEDU Uncharacterized protein OS=Paenibacillus durus GN=PDUR_22590 PE=4 SV=1 +---------AYDDIKQRPQLCVTLLRMVLSRYRPSAApvsr--AVLAEKEVLRLAIHAAkPLRPVDVARHFEVDSKTAVQILKKLCAKGLLNPVRRGKSERAVGYELSNGVLDYY------------------------------------------ +>tr|E0I786|E0I786_9BACL Putative uncharacterized protein OS=Paenibacillus curdlanolyticus YK9 GN=PaecuDRAFT_1510 PE=4 SV=1 +---------SVDDLEEQQRRCQQMLMHILGKWYGSAGnatllEQLTPRENQLLNIIVEKGtVMTPKQVANETGMHQAYVRRLLKSMVEKGYLQPV-G-GAlaTRIRSYKPTFVYERNK------------------------------------------ +>tr|A0A0Q9TN35|A0A0Q9TN35_9BACL Uncharacterized protein OS=Paenibacillus sp. Soil787 GN=ASG93_24920 PE=4 SV=1 +---------AYDDVKNRPRMCEQLLQQCIGRHFGDVFnqeIELNFIEKEIIRFGLTLGrPIKPTDVQKQFQFRQRKAQETLKGMYQKSLLEPVGA-GHARVRGYSVAQH-VLAS------------------------------------------ +>tr|A0A0B0I218|A0A0B0I218_9BACL Uncharacterized protein OS=Paenibacillus sp. P1XP2 GN=CM49_01169 PE=4 SV=1 +---------AYLSIRDDPGVCKQLVLSFVGKFLSS-AvpFGLHWAEAETLRYAHRLLrPFTPMELSSHLQLSEHRTRVILRALLEKKLL-EVASG-KQRYRTYRLPGDHVQSP------------------------------------------ +>tr|A0A089K9W1|A0A089K9W1_9BACL Uncharacterized protein OS=Paenibacillus sp. FSL R7-0273 GN=R70723_08285 PE=4 SV=1 +---------PYDDLESASDLTISLFKSLLAPSLLINTdeleHHYTRLERDIMRAVVRWNgMIRPVDLANGLRVHPRTIRKSLTRLCEKGKLRPVPASGSSRICRYEYVPSIMNNG------------------------------------------ +>tr|C6CV44|C6CV44_PAESJ Uncharacterized protein OS=Paenibacillus sp. (strain JDR-2) GN=Pjdr2_0878 PE=4 SV=1 +---------SAWQVEHQPQQCIVKVKQAIGHWWSLTYqrdlkqttNIWEIRKQWIIQMALRQQgKIRPGDVAQEFQISNRTAVDWLHRLETAKLLQRLP--AKHRVTTYVLADYVAST------------------------------------------- +>tr|A0A197ZYC1|A0A197ZYC1_9BACL Uncharacterized protein OS=Paenibacillus sp. 1ZS3-15 GN=A8708_25130 PE=4 SV=1 +---------SLDDIRERPRLWQALLQQLIGRLFGEHEstaSHLSGQERDILRLALRMDrPIKLADVKDVLCCGYDTARKYIKRLEEKKWLLPEVK-GAARIHTWIVDTTRRPPL------------------------------------------ +>tr|C6CW25|C6CW25_PAESJ Uncharacterized protein OS=Paenibacillus sp. (strain JDR-2) GN=Pjdr2_1213 PE=4 SV=1 +---------SYDDICDRPRMCEQIVQQFMSTWLDRHYterSSDAIIQHEVLRLALRTEkPLRAREVSTYLTVHIETARSILRELAKLNLLLPCGG-GKQRVHSYVVNKENL-DD------------------------------------------ +>tr|A0A0P9CAI7|A0A0P9CAI7_9BACL Uncharacterized protein OS=Alicyclobacillus ferrooxydans GN=AN477_17520 PE=4 SV=1 +---------TYHDITTSARQCEHIIRQARGDIIARS-tafKDTTPYERDIIRLAIRSTqPITAQDVRSYLNISRDYSFNLLHGLTERKWLLPSR--GTRRINSYVLHPSKRNIR------------------------------------------ +>tr|L0EC79|L0EC79_THECK Uncharacterized protein OS=Thermobacillus composti (strain DSM 18247 / JCM 13945 / KWC4) GN=Theco_0580 PE=4 SV=1 +---------SYDDICGRPQLCRTVIQKLLGLCYGADDk-SLPLPQRELIRRAMRHGrPFTPDDAAEWTGLSKRTVGPMLHRLRMQGYVEPA-S-GKVRIRRYALTLKAERLG------------------------------------------ +>tr|A0A1C0ZW30|A0A1C0ZW30_9BACL Uncharacterized protein OS=Paenibacillus pectinilyticus GN=A8709_31280 PE=4 SV=1 +---------SLDDVKNRPRMCEQILQQCIGKYFGDFFsqdHSMSYIEREIIRLANSIEkPIRPVDIQKSFQFGQGKSQRILKAMCAKAFLKPAGQ-GTSRIRSYSVNQTLVLAS------------------------------------------ +>tr|A0A1C1A5F0|A0A1C1A5F0_9BACL Uncharacterized protein OS=Paenibacillus pectinilyticus GN=A8709_14050 PE=4 SV=1 +---------SLDDIKYNPRKCQQTIMQAAAKWGLDDTkhlLQLIPTEYAVWKWVENQDdLVTPISVAKALRINRETSTKYLKSLVLKGLILPASR-EGKKIMRYRAKSSGRTNG------------------------------------------ +>tr|A0A1I7G6C9|A0A1I7G6C9_9BACL Uncharacterized protein OS=Alicyclobacillus macrosporangiidus GN=SAMN05421543_10223 PE=4 SV=1 +---------PTHDLANNPRHCQQTIQQLFGRLFSTQNesfHELNSLDREILRIFSKWPdLMGPKRIAELLHVSSDTASRHLRNLASKRWLDPLG--GKQRVRLYRLNPNRRLDR------------------------------------------ +>tr|A0A1Y5KJ01|A0A1Y5KJ01_9BACL Transcriptional regulator OS=Paenibacillus sp. MY03 GN=B1748_00775 PE=4 SV=1 +---------AYLSIRDEPEFCKQLLLSFVGKFLSI-NvdAGLNGLEAETVRFARRKLrPFTPNELAEHLRITDRYARMLLHRLVEGQQI-TVVGG-NIRFRTYQLNMGGLLGP------------------------------------------ +>tr|A1B2F6|A1B2F6_PARDP Transcriptional regulator, LysR family OS=Paracoccus denitrificans (strain Pd 1222) GN=Pden_1600 PE=4 SV=1 +---------------------------------------MDINHLRTFVTVVREGSITRA--SEILYRSQPAISAHIKSMEDSlgiKLFERNPR-------GMTVTQGGSRLLAVADKLLEQHQRFL---------------------------- +>tr|W0H4B3|W0H4B3_PSECI Transcriptional regulator OS=Pseudomonas cichorii JBC1 GN=PCH70_21240 PE=4 SV=1 +--------------------------------------------IQAFEQTARFGNVARA--AEQLNLTPSAVSHQLAKLESMIGRQLFL----RTARGVSLTPVGEQYLSEISGILHSFAVATERAASDISLDCLR--------------- +>tr|A0A1S1FPP0|A0A1S1FPP0_9PAST Transcriptional regulator OS=Haemophilus sp. HMSC61B11 GN=HMPREF3263_06720 PE=4 SV=1 +--------------------------------------------LKSFESAARHLSFTKA--ADELFVTQAAVSHQIKLLEDFLGVELFI----RKNRSLELTEFGKAYFVDINKVLRKLNEATERLLTLKAEPHLA--------------- +>tr|A0A0A7SZF1|A0A0A7SZF1_LACLL DeoR faimly transcriptional regulator OS=Lactococcus lactis subsp. lactis GN=E34_1882 PE=4 SV=1 +-------------------------------------------KRRIVDYLKLKRRATIEELLTLMDCSISTLRRDLNELEKEKSLRRVHGG------------------------------------------------------------ +>tr|A0A226C5J2|A0A226C5J2_ENTFC DeoR family transcriptional regulator (Fragment) OS=Enterococcus faecium GN=A5848_001456 PE=4 SV=1 +-------------------------------------------QERIITLLEKDFYLTNSEIANKLGVSEMTIRRDVTELAKKNKVKKLYGG------------------------------------------------------------ +>tr|A0A1C4UKQ8|A0A1C4UKQ8_9ACTN DNA-binding transcriptional regulator, PadR family OS=Micromonospora chaiyaphumensis GN=GA0070214_101786 PE=4 SV=1 +----------------------------------------------ILVSLLEQP-ASGYELARRFDRsigrfwtaTHQQIYRVLKRMEHDDWLTAEEVGQEGLpdKKVWSVTPTGRSALVA---------------------------------------- +>tr|A0A0N0KCD0|A0A0N0KCD0_9SPHN Uncharacterized protein OS=Novosphingobium sp. AAP83 GN=IP81_18090 PE=4 SV=1 +---------------------------------------ISFQQLRLFESVGRLESVRKG--SDECNLSQPAVTQALSKLERQvgfALLERRAS-------GSYLTEAGTVLHLRVCRMFAQMASAVMAIGEAKGVEQASVIVNRL--------- +>tr|W6VWU5|W6VWU5_9RHIZ Transcriptional regulator, LysR family OS=Rhizobium sp. CF080 GN=PMI07_001929 PE=4 SV=1 +---------------------------------------PNLRHLRMLQVIGRTQGIGSA--AREMNTSQPAVTLAVATVESElgiEVFERGGS-------GTFPTSAGRLLLARVSRFFDILEAALLRVAG-DAApqRRpLPPVERVM--------- +>tr|A0A0C2TM58|A0A0C2TM58_BACPU Uncharacterized protein OS=Bacillus pumilus GN=B4127_1288 PE=4 SV=1 +------------------------------------------------AHLYYTDGWTQQEIAKKLNVSRPVISKLLQKAKDVGIVEVYIKDESIHTVELE--------------------------------------------------- +>tr|A0A0K8JGR9|A0A0K8JGR9_9FIRM Uncharacterized protein OS=Propionispora sp. Iso2/2 GN=P22_2907 PE=4 SV=1 +------------------------------------------------LNMHFIEGLTQSQIAKAFHVSNTIISRKINKARDYNLIDYFFKDETSFTVNLE--------------------------------------------------- +>tr|F2J6A0|F2J6A0_POLGS Putative LysR family transcriptional regulator OS=Polymorphum gilvum (strain LMG 25793 / CGMCC 1.9160 / SL003B-26A1) GN=SL003B_ +-------------VVARAARALGYIREAAQRIArrcrsegsstpDLLETHATISHLRAASLVAHTGSFSAA--ARALGQSEPSVHRAAREIEGILGVTLFD----EAYRRLQTTPAGRTLATAASLVLKELDN------------------------------ +>tr|A0A0Q6X8E0|A0A0Q6X8E0_9BURK Uncharacterized protein OS=Rhizobacter sp. Root1221 GN=ASC87_21430 PE=4 SV=1 +-------------IAQRAQRLFDHLEAGATEAValmpegegrdgmqGRFCASVSAASLKALVAIAASASEAHA--AQALGQSQPSVHRALRDLESLARARLLW----KSVRGTRLTDAGEAMLRRVKLAFAEMRA------------------------------ +>tr|A0A0T6YTS4|A0A0T6YTS4_9RHIZ Uncharacterized protein OS=Sinorhizobium sp. GL2 GN=N182_21440 PE=4 SV=1 +-------------YLLRIDRFFEILDNALAHAMgrlgdapdrmPKVERLMTGTQLRALVVTCEQGRVREI--AHSLGLSPASLFRSARSLEHALGKPLFD----RTAQGPIPNRTGNFLAREFRRAIREIEM------------------------------ +>tr|A0A198UE06|A0A198UE06_MORCA Transcriptional regulator associated with utilization of aromatic, LysR family OS=Moraxella catarrhalis GN=AO384_1987 PE=4 SV=1 +-------------YVNRVKRSLAILKYGLIDVLrmqdfgiqksDYLFHHLTNTQLKAFITVAETSNYTHA--AKKIGTSQSSVYRSIQELQHLLNLKLFE----KTSLGLKLSKIGLIFYQSCKLATAELAQ------------------------------ +>tr|F7X832|F7X832_SINMM Transcriptional regulator OS=Sinorhizobium meliloti (strain SM11) GN=fldY PE=4 SV=1 +-------------LLMRLRRMENQIASALAELFgvssqrdptlvAKCLARIGFRQIEALIALSGSGSITEA--ARSGGGSPAALHRALHDLQTNIGRAILM----RSPAGVAPNALGRRLAIRWQVALTELEQ------------------------------ +>tr|A0A1J0RZA1|A0A1J0RZA1_9ALTE LysR family transcriptional regulator OS=Alteromonas mediterranea GN=BM524_00460 PE=4 SV=1 +-------------FLTRANRAFEHLHEFAFTLYstdkrkrQSLVRSITSRQLNSFVKVAETHSYTIA--AARLGLSQPTLHKSIKNLETLCEQSLFH----RSPAGVEPTWRARQLRRFANLFIAEIQQ------------------------------ +>tr|A0A1E3ZDG6|A0A1E3ZDG6_9BORD Uncharacterized protein OS=Bordetella sp. SCN 67-23 GN=ABS43_13600 PE=4 SV=1 +-------------LHRRTELAFAELQQACDVLSarypesaprlrtaPFFFLAVHERRLELLFAFTERKHISTA--AAAVGVSQPAASMALYDLEASVGVPLFD----RAHAGVALNESGELLLAHVKRALAQLRL------------------------------ +>tr|A0A1E4GG92|A0A1E4GG92_9RHIZ Uncharacterized protein OS=Pelagibacterium sp. SCN 64-44 GN=ABS76_07545 PE=4 SV=1 +-------------AYRRVSRFHRELGEAVMGVGagaqdae-QRLSRITNLHISTHLAMADDPMLAFV--PQALGVMPATSLRAIRELERTLGAQLYE----QTSEGRVVTRKGRELARQLGLAVREIDL------------------------------ +>tr|A0A1Y0L8B9|A0A1Y0L8B9_TATCI LysR family transcriptional regulator OS=Tatumella citrea GN=A7K98_11210 PE=4 SV=1 +-------------ILPRARRAIEELHQVAVTLHklqskngnsrsmTEPLYLFNVNRLQIFVSLCQTRHMQTV--AKLLGLSQPAVSAALRVMENGAEMPLLQ----RTPQGMIPGIAGQEILPYIRRALNELRH------------------------------ +>tr|A0A081BWG4|A0A081BWG4_9BACT Uncharacterized protein OS=bacterium UASB270 GN=U27_03632 PE=4 SV=1 +-----------------------------------------NTRLRIVWLLKRAGtALCVCEIMDALHESQYNISRHLKELRIAGVVQDQKQ---GRWNFYTLADSSSQFEQLVLQAVAALTSDALEL------------------------- +>tr|Q5E1H7|Q5E1H7_VIBF1 Transcriptional regulator, ArsR family OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=VF_A0049 PE=4 SV=1 +-----------------------------------------PNRLRLFWLFLHVDeCIAVAEALDIIGDTQYNVSRNLKMLYRAGLLNHQKK---GKWVFYTLKEQAAPHCKALVDSVRFLPKDEFEE------------------------- +>tr|A0A1G3KSF4|A0A1G3KSF4_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWB1_27_13 GN=A2Z98_04980 PE=4 SV=1 +-----------------------------------------ETRIRILKVIIQSKtELCVCEIVDSLQIPFYTISKHIKELKNAEILSETKE---GKFVLYSFVDKKDDFLNKIIDLIKSIPDEFFSN------------------------- +>tr|A0A1F7SNS6|A0A1F7SNS6_9BACT Uncharacterized protein OS=Candidatus Schekmanbacteria bacterium RIFCSPLOWO2_12_FULL_38_15 GN=A3G31_01865 PE=4 SV=1 +-----------------------------------------ENRLRIFNLVLLSNqEIFAGEISNALKKPQYTISRHIGILIKSGLIKQRRD---GARIFYSLSEKTKELRINLLQFLDMiggDFQNIFKE------------------------- diff --git a/esm/source/examples/data/few_proteins.fasta b/esm/source/examples/data/few_proteins.fasta new file mode 100644 index 0000000000000000000000000000000000000000..e9be9f55e35bfee1692537a8d5b92ca1369700f8 --- /dev/null +++ b/esm/source/examples/data/few_proteins.fasta @@ -0,0 +1,6 @@ +>UniRef50_UPI0003108055 +MPADAREYLESKHATRRFDRPAEVAGVVAFLLSDDTSFVIGAGYLVDGGYTALRAARGRLGPRRQAAPAVKLLPNTDSPR +>UniRef50_A0A223SCH7 +MGPPRWWKGITGLAAVVHRADPEDKADLYAKMGLYLEYHPETRIVEARIKPRLHDVCESKVSEGGLEPPCP +>UniRef50_A0A090SUK6 +MKTPEDRVFRATDEYSDFVMACRYKGNEREFVIASHDKLNEAQVETLTSYLSGEWFKKTYITGIMNDSDGVLSQHEEYGDEVFCQPLDELRVDRYIMMV diff --git a/esm/source/examples/data/hhblits_uniclust_2017_10_1a3a_1_A.a3m b/esm/source/examples/data/hhblits_uniclust_2017_10_1a3a_1_A.a3m new file mode 100644 index 0000000000000000000000000000000000000000..324bb4ecd462a0211cba5457dd3087888b50a873 --- /dev/null +++ b/esm/source/examples/data/hhblits_uniclust_2017_10_1a3a_1_A.a3m @@ -0,0 +1,2606 @@ +>1a3a_1_A +LFKLGAENIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKTGVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTTSVDEVLELLAGRK +>tr|E6MGJ6|E6MGJ6_9FIRM PTS system, mannitol-specific IIC component OS=Pseudoramibacter alactolyticus ATCC 23263 GN=mtlA PE=4 SV=1 +---LIKKNIRLNRSPQTKEAIIRDIGKVFYDGGYTTEKYTEAMLEKEKVFNTAIGNNLAIPHGIEGMTGEILNSGLVIFSYPDGVDWGDG--QSVKLVIGIASVGDEHVDKLAKIAAACNTEEAVNKILAM-DVDDVYDLFK--- +>tr|D4YFK9|D4YFK9_9LACT PTS system, mannitol-specific IIC component OS=Aerococcus viridans ATCC 11563 = CCUG 4311 GN=mtlA PE=4 SV=1 +---I--Q-VPFHED---------------------------------KPSASVMAASNL----RNELKKAGSDLVAEAVPFAQLQNNS-----QTLIIVDADTVHPA---------KEVAPEAQFEEVSKLYEQNQYNKLLN--- +>tr|A0A0R2GJW7|A0A0R2GJW7_9LACO PTS system, mannitol-specific IIBC component OS=Lactobacillus acetotolerans DSM 20749 = JCM 3825 GN=FC77_GL000644 PE=4 SV=1 +---VKEVNFIRHDE---------------------------------HLGSATMATSLF----SDAMKKAGKKTPVKAVKINELDDDP-S--H--LVIVTPAAKKNL---------KLRYADIQIITVDDLLQDKKLKQIVD--- +>tr|A0A0N1CMM5|A0A0N1CMM5_9ENTE PTS sugar transporter OS=Enterococcus sp. RIT-PI-f GN=AEQ18_02700 PE=4 SV=1 +---IYIASEELAKTVDAKGAALFAVNDMLQMEQYRQLLTEGADYVLNQTRNDFIN------------------------------------------------------------------------------------------ +>tr|A0A1W7R1T6|A0A1W7R1T6_STRMG PTS system mannitol-specific EIICB component OS=Streptococcus mutans GN=mtlA PE=4 SV=1 +---IDAV-VFAHGI---------------------------------AKGSATMGQETL----RSIFKQNNVKIPVSTASYAHLSDYN-A--KNILLVTTIAQQGQA---------QQAAPNAQILVVDSLVTTPEYDKLVA--- +>tr|A0A223NA51|A0A223NA51_ENTFL PTS mannitol transporter subunit IICBA OS=Enterococcus faecalis GN=ADH73_12195 PE=4 SV=1 +---VNEI-LLVHDD---------------------------------RVGSATMGMKVL----EEILDKEKISMPIRKININELTQQT-Q----ALIVTKAELTEQA---------RKKAPKATHLSVKSMVNPQKYETVVS--- +>tr|H3K7Z9|H3K7Z9_9FIRM PTS system, fructose subfamily, IIA component OS=Megamonas funiformis YIT 11815 GN=HMPREF9454_01372 PE=4 SV=1 +---LIKDNILLNLSVSSKLDAFKELSSKLLINNCINdqKEYINALIKREQEFSTNIGFGIAIPHAKDK---SVNKASIAIGTFSPGLNYEDGEapVKLMFLLAVPTESDNLHLEILKRLSRKIIDTKFRENLLSAKTVNDIFKIME--- +>tr|A0A142B976|A0A142B976_9GAMM Fructose PTS diphosphoryl transfer protein OS=Endozoicomonas montiporae CL-33 GN=fruB PE=4 SV=1 +---LLKSHIFLQQFAPSKYQALKLACLKLVEAGMVCPGYFHGMCRRELLSSTYLDNGIAVPHSVPDt-RSEINYSGMIIIQFPRGVNWGNND--RTFLLCALAARGKEHLQMLSHLACSLDDTDLCRKLAVTEEVEHIYQSVT--- +>tr|A0A1C6GBT2|A0A1C6GBT2_9FIRM Pseudo-HPr OS=uncultured Eubacterium sp. GN=fruB PE=4 SV=1 +---LndeFQKHICLDFECTTIEEAIRKAGDLLVQCGCIKPPYIDGMIRREQEHSTHIGFGVMIPHGTEDTLDCVISPGISILKISNGVPYHGT---MITMVIGIASREEDPLQELMQITDILLTPEKCDQFLNASSKQEFIDMIN--- +>tr|R5ZC79|R5ZC79_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system OS=Lachnospiraceae bacterium CAG:25 GN=BN562_00059 PE=4 SV=1 +--NEFQKHICLDYECTTIEEAIHKAGDLLVQVGCVKPPYINGMIRREQETSTDIGLGVMIPHGTEDTLNFVLKPGISIVQIPHGVSYHGN---TIHLVIGISSREEDSLQELMQITDILLKPEKCHQFLNASSKQEFIDMINQ-- +>tr|S6G7V8|S6G7V8_9MOLU Phosphotransferase system PTS, mannitol-specific IIA component OS=Mycoplasma yeatsii 13926 GN=mtlF PE=4 SV=1 +--IKNKESVFLIDKFNSKIEAIEFVGNKMVELGYVDKQYIDSMIERDKTASVAIGNYLAIPHGNSDGFKYIKNSGILVVKLKEALTWDDEKV---NWIVALALEGDNQLEALQNLAIAFSEKSEVESMNKNlNTLDEIFDFFSN-- +>tr|A0A094P635|A0A094P635_9ACTN Uncharacterized protein OS=actinobacterium acMicro-4 GN=GM43_5035 PE=4 SV=1 +--LLQTAGIVLDATASSREEAVAVCGSLLRELGAIEPEYAEAMWEREQIFPSEIGGGFAIPHGTDKSRQYVLFDQLVFVRFLEPIAWVNE---QVSVAIGIAAAGDGHVEILGNLAEILLDDASAHVLLSSTSEEEIRSLLVK-- +>tr|A0A1B8W3N3|A0A1B8W3N3_9BACI PTS mannitol transporter subunit IIA OS=Bacillus sp. FJAT-26390 GN=A7975_20050 PE=4 SV=1 +--ILSTEKVKLNVSVKDKYEAIRMVGQMLVDAGHAPQAYIDKMIEREEALSTYIGGGLAMPHGTNDSKALIQSTGMAIIIVPAGVDFGGEE--PAQLVIGLAAVGDDHLDILTNVAVLVSEEEDMQRILNASSPQELISIFES-- +>tr|A0A1V8Z8C0|A0A1V8Z8C0_ENTGA PTS mannitol transporter subunit IIA OS=Enterococcus gallinarum GN=BH745_02185 PE=4 SV=1 +--DIPATHILLDQRFQSAEEALHEIGTFLVDQKMVQPQYINSLIQRHKKYGVYIGNFVALPHGEEEADKWINEEGICLVQVPDGVDFGDAKEsKVTTILFVVVLKE-KQLSCLQEIAFFCSDIQNIKLLSDAATIEEVQKILSL-- +>tr|A0A1Y4S5X7|A0A1Y4S5X7_9FIRM PTS mannitol transporter subunit IIA OS=Lachnoclostridium sp. An131 GN=B5E77_14105 PE=4 SV=1 +--VLTVNNIVLGADYPDRWEAIRACGEILFQQGYIRGEYIDDMMERERLFGVYMGNGIAIPHGVEGSERNILHSGISVLQLKRGVDFGTG---TAYLLFGIAGKDGEHIELLSRIAQVCMETEKVERMRITEDKEEMLQILNS-- +>tr|A0A1X1D3B0|A0A1X1D3B0_9GAMM Uncharacterized protein OS=Pantoea rwandensis GN=HA51_04045 PE=4 SV=1 +-IKVTTDEITLGCKADSRAEALLIAANALINRGLVKPNFAQALLNREDETSTWVGGGVAMPHAARKNIDTVIETGYHFLQFPDGIKWER--GRVAFLVVVIAAKLNEHLDVLSGIAELLSDEMQASLLSSCKTEDEFISLLE--- +>tr|A0A0C5BG42|A0A0C5BG42_9MICO PTS mannitol transporter subunit IIA OS=Rathayibacter toxicus GN=VT73_03835 PE=4 SV=1 +---LTLGQIDPSGAATTKEAAIKEAADLLVRAEAVTSTYYQAMLAREATISTFMGNLLAIPHGTNDATREIRFSALSFVRYAQPIDWDG---HEVRFVMGIAGINNVHIEMLSKIALLFSENDEVQKLLDAPDAQTLYHLLSG-- +>tr|A0A1G4VK15|A0A1G4VK15_9MICO PTS system, mannitol-specific IIA component OS=Candidatus Aquiluna sp. UB-MaderosW2red GN=SAMN05216534_0608 PE=4 SV=1 +---IQQAGIQLAAAASSSEEAVASCGQLLFELGAIETEYAAAMWEREQIFSSAIGMGFAIPHGTDESRKFVNFDQLVFLRLENPIMWGD---EEVYCVLGIASQGDAHVDILGNLAELIQDPAHLATLMNSNSPSEILDLLLS-- +>tr|F7NGX7|F7NGX7_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Acetonema longum DSM 6540 GN=ALO_06593 PE=4 SV=1 +----ERNLIFIKTDFRDKTAVVEFLGGQLVQAGAVQPAYVQAMHQREQDVGTYITEGVAIPHGTEGSRSLVNRAAIVALKIPRGIEWSDG--KPVFLAFGIAGNEEDHVSLLSELAIMLMDADQKAKLLAAENEDDLFACLNQ-- +>tr|A0A1H3FJJ8|A0A1H3FJJ8_9FIRM PTS system, mannitol-specific IIA component OS=Lachnobacterium bovis DSM 14045 GN=SAMN02910414_00255 PE=4 SV=1 +----KKEMIFLDLDLKNKEEVIRFLGNKLYEQGNITKDYVESMIKREQEMSTYLKNGIALPHGIMSEsLEGIYENGVALAVINNEIEWDQG--NTVKIVLAIAADRITHMDILAKIAKIASDNEKINKLLTMSEDEIVLNFNK--- +>tr|A0A0K5Q8U8|A0A0K5Q8U8_ECOLX Putative DNA-binding protein OS=Escherichia coli GN=ERS085365_00947 PE=4 SV=1 +MKTFPLQSLTIIEAQQKQFALVDSI-------------------CRHFPGSEFLTGGdLGLTPGLNQPRVTQRVEQV--------------------------------------------------------------------- +>tr|A0A0B8Q9X2|A0A0B8Q9X2_9VIBR Fructose-specific phosphocarrier protein OS=Vibrio sp. JCM 19236 GN=JCM19236_1408 PE=4 SV=1 +MAE------------CKKFE------SNIRVAN-------------------LDGDGKV-----VNAKSLMKVIALGVKHGHQLqftAEGS--DAAEALASIGKAIESGLGEG----------------------------------- +>tr|A0A1B9JXI1|A0A1B9JXI1_9GAMM Uncharacterized protein OS=Gilliamella apicola GN=A9G12_11915 PE=4 SV=1 +-LTINRSNYYLNCKAENKKDALRIISDEFIKSKNVTTDCFYALSKRENQISTYISNGVAIPHLSKDDRTIILKSDIKVFQFPQGVMWGES--HIVFITIAVLSKNdNDHIDTLKALTPLIKNDVAIDILSVTKHVDDFDKILSR-- +>tr|F5SXT3|F5SXT3_9GAMM Phosphoenolpyruvate-protein phosphotransferase of PTS system OS=Methylophaga aminisulfidivorans MP GN=MAMP_02307 PE=3 SV=1 +-ELDLVQIVQLNVSATDKETVIEQATQLLVENNCVDPAFAQSMKQRETRANTFLGRGISIPHGIAEDRHLIKKDAVAILQIPQGVEWNP-G-QIAYMVVAIAAQTDGHITLLQTLTGLLQNDEQLQQLFKTDDEQLIVTSLNNS- +>tr|A0A1B8PXI6|A0A1B8PXI6_MORLA Phosphoenolpyruvate--protein phosphotransferase OS=Moraxella lacunata GN=A9309_09305 PE=3 SV=1 +-LNLTATDVRMNAQATNKDEALSLLAKILSEDGLATADYLAGLQAREAQTSTYLGQGIAIPHGTPESRACVQQTGVRLVHFADGVVWNDDG-ERAYLLVGICAKSDEHLSILRQLTRTLGD-DVADDIKNAKTAEQIITIINGD- +>tr|A0A1C0BVU3|A0A1C0BVU3_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium MTC7 GN=A4S06_02000 PE=4 SV=1 +---LNKDCIEVNCKKVERRQAIDDIGQTLLEAGFIEEPYIDGMHKRDESLTTFIGNDIAIPHGEYEVKPFVKQTGLAVKVYPEAIDWNG---NPVRVVIGIAAKDSDHLDILSNIAVKLGEMDVVEELVNSHDVDLIHRTLTRE- +>tr|A0A0M4M4K3|A0A0M4M4K3_9RHIZ Phosphoenolpyruvate-protein phosphotransferase of PTS system OS=Bartonella ancashensis GN=PU02_0003 PE=3 SV=1 +-DILSLKSIQLSAVFSHKNDAIYAAVKLLMGSDVIKQHHLGGIIGsklITNVASIWFRSGVAVIYGITESYQLVMRDAVSVVQIPAGVEWQDER--RVYLVIAVITCADLHIKILKKIAPILFDEQKLKELSVIEDKQKIITALLG-- +>tr|A0A090RPD6|A0A090RPD6_9VIBR Fructose-specific phosphocarrier protein HPr /PTS systemfructose-specific IIA component OS=Vibrio maritimus GN=JCM19235_5680 PE +MLQLDTNTITLNQSSDNKLNAIKAIAADLTSKGLVQDGYVDGMLNREGQNSTFLGNGIAIPHGTTDTRDLVKQTGVAVHHFPNGVDWGDG--NVAYVAIGIAAKSDEHLGILKQLTKILSADGVEQKLKQAKSEKDIIALLNGDV +>tr|W1KAF3|W1KAF3_9ENTE PTS system ascorbate-specific transporter subunit IIA OS=Enterococcus durans IPLA 655 GN=H318_02540 PE=4 SV=1 +---VDKSLIQIDVEAENFEDAVRKSMEPLVAQKYVKPSYVEKILSIYRETGPYIviTTHIALPHADSE--AGALKMGMGFTKLKHPVISGNVANDPVKYLFPLSATDsTKHIQMLSKLAELLGDPSFVEGLDTVTSKEEFIALLTK-- +>tr|C4FP02|C4FP02_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Veillonella dispar ATCC 17748 GN=VEIDISOL_00624 PE=4 S +---LSEDNVSFHYPAETWEEVIRHGGQLMVDAGFTDPSYTEAMVEVVREMGPYIvlAPGLAMPHARPE--NGAKRVGTALVTLEKPLNFGSPDNDPVSVALFLCAPNkDEHIQLLTDIATLFEDDEFLDAAADFESIEDVQAFLAE-- +>tr|A5KJK6|A5KJK6_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Ruminococcus torques ATCC 27756 GN=RUMTOR_00404 PE=4 S +---LTEEMVRLDPPlLSTPEEVIEYCGNILVENKKAKAGYVKEMIDSYQRFGPYMvmAPGLALPHARPG--GNVKEPCISFVKLKEPVCFHHPCNDPVWVVFALGGVSdDGHIELLQDLSSLLAGERMIEKLAALNTYEELEKLMEK-- +>tr|L0K9H6|L0K9H6_HALHC Phosphotransferase system mannitol/fructose-specifc IIA component (Ntr-type) OS=Halobacteroides halobius (strain ATCC 35273 / D +---LNSKNIKTSVEVNDWEEAVEISGSMLVDNGLVKPSYIESMKDMIKKEGAYVviSPGLAIPHARPE--KGVLEPGISLITLKTPVEFGHSKNDPVKVVIAFCASDdSSHVEMMRELVTFLNANKNLQYLKEANNKDKLISYIQN-- +>tr|N1ZVP7|N1ZVP7_9LACO Uncharacterized protein OS=Lactobacillus murinus ASF361 GN=C822_01617 PE=4 SV=1 +---YDNNLVAISKKtPKDWEEAIRLSGEILKQNELITDQYVDQVINDVKEYGPYIviVPGVAMPHSSAKN-EGVLGTGIGFTLLPEAVSFEagNP-EKDAQLFFMLAAKDsAAHMENIANLSDLLMTEGLIADLKKVKTMEDYITVMEK-- +>tr|R7GA98|R7GA98_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Eubacterium dolichum CAG:375 GN=BN631_00349 PE=4 SV=1 +---LTQESVQYIE-cVESWKEAVVICVQPLIDQGKVDCEYISAVNRNIERYGSNFviYPYIILPHARPE--QGVKENAVSILLTKTPFHFDDN-KTPVRLVIVMAPMDsKSHLQILKEISGMLYDRNSIQSIMESKSKGQLYQRIRE-- +>tr|E1QXS4|E1QXS4_OLSUV Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Olsenella uli (strain ATCC 49627 / DSM 7084 / CIP 109912 / JCM 12494 +---LKRENVQVVETCGGWEDAIAVAVQPLVDGGYVTPAYVEGIIENTHKFGPYFvlAPDLALLHARPE--QGVISQQLAVTVLREGVEFKEG--EPVRVLVTLAAENpDSHIDVMRVLATMFSDPKNIEKVATASTADDIFGFFVS-- +>tr|G5IBC0|G5IBC0_9CLOT Uncharacterized protein OS=Hungatella hathewayi WAL-18680 GN=HMPREF9473_00842 PE=4 SV=1 +---IFRDIRVCGEHFPDWKAVVDYVGETFVAKGYAKREYFEYIKKDMVENEAYMviVPHFALLHSAPE--HGALENVFHFMKLEHPVEFGHESNDPVAYVITFTSVDaDSHIAGISLLAGMLMKEGFVEELSRAGSDESLAACIRK-- +>tr|A0A174SCY9|A0A174SCY9_9FIRM Putative PTS system L-ascorbate family, IIA component OS=Flavonifractor plautii GN=ulaC PE=4 SV=1 +---ITDQSYL-EDVvCADWEELVEIGGGLLVKQGSVEPRFIQSIKDTIAEFGAYMvlVDDIAFFHGRPE--AGVKETSMSLALLRNPVYLS---EKRIKAAFTFAAVDkSSHLELMRELGGYLQDESFMDLLRNHGGKTAIMERLHK-- +>tr|Q8EVW1|Q8EVW1_MYCPE PTS system enzyme IIA component OS=Mycoplasma penetrans (strain HF-2) GN=MYPE4480 PE=4 SV=1 +---MTSNDLIAFHKgNISWQESIRLAVSLLVKNNIAESGLADEIIKSTLKYGPYYviAEKVALAHTAVC--EYNKKPGMSLVIFENAIKFSeNQ-KHEVNLLFCMSAIDsDSHMGILQKFANTLSQKDIVSKILNESDKTKIYEIFKG-- +>tr|B2Q496|B2Q496_PROST Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Providencia stuartii ATCC 25827 GN=PROSTU_01970 PE=4 S +---DDAKWIQINQVAADWKEALSIACTPLIIHGAAEPNYLQGIIKNTQSWGPYYliAPGIAMPHARPE--QGAIYNQITLTTLKQPVVFGHEDCDPVWLLMTVCATQsDDHIRLIQYIAELIDNPLLLDEIRCAKTHDDVLRLLNS-- +>tr|A0A1H1N4F5|A0A1H1N4F5_9ACTN PTS system IIA component, L-Asc family OS=Olsenella umbonata GN=SAMN04489857_1689 PE=4 SV=1 +---LKVENIQILDSVQDWREGVRVSLDPLVKGGYAEQRYADNVVKDIESVGPYVvlTDDIALIHARPE--EGAIKTQMGLLLLRKPVQFEGSD-SCVTLLFALSAEDpNSHVDAIKVLATFCMDESKVARLKESETPEEIYHLLIA-- +>tr|S5ZEX4|S5ZEX4_9CREN Uncharacterized protein OS=Thermofilum adornatus GN=N186_06725 PE=4 SV=1 +---AVEERIKVVEVVSDWKEAVILAGKLLQRDNCIEESYIEGMIKTCQELGPYIaiAPGLAIPHARPE--EGAQKTCFSILVVRKGVNFGS-HNDPVYIVVAFSSPDkKSHLKFLQVLAELFANKGEqiVNSLREAKNTYEALSILRE-- +>tr|A0A1W1YK31|A0A1W1YK31_9LACT Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Aerococcus suis GN=SAMN04487984_0746 PE=4 SV=1 +---LDQMYIQIY-DsLPSWREALYLAGEPLLHANIISRHYLKQIEAAAEFLGPYMdvGRGIGFMHARPE--EN-ESWGISLLKLQEPVYLLdQT-NHPLKIVIVFKGKDaKQHLKILQVLSEWLANPLQYQFVCEATSPESIINSIKQ-- +>tr|A0A1Y0L1G2|A0A1Y0L1G2_9MOLU PTS ascorbate transporter subunit IIA OS=Spiroplasma clarkii GN=sgaA PE=4 SV=1 +---MDK-QFCKIINkTMSWAEAIKASAQTLLEENYFNENYVIEMIENVKKFGSYIviAPKIALPHASYS--KNVFKGGFSITIFPLGIDFQAS-SGPVYILVTISSTNnEEHLQRLKEISSKLSNQAVVTSLLEAQSSEIVWEKWNE-- +>tr|A0A1C6Z4I9|A0A1C6Z4I9_HAFAL PTS system, mannitol-specific IIA component/PTS system, ascorbate-specific IIA component OS=Hafnia alvei GN=BN1044_03651 PE=4 S +-----ENAFHVVDSVDDWRHAIDIVTAPLTASHRIEARYCTAIKTATqELGPYYvLGAGVAMPHARPE--EGVIDTALSMVLVRGGVDFGT-GTEKVTILICLAAKDaDSHIYAIQALCEILSDGEVINEINNACDALALQEIIK--- +>tr|A0A0F4KYB4|A0A0F4KYB4_9LACO PTS Asc IIA OS=Lactobacillus mellis GN=JG29_00350 PE=4 SV=1 +---LSPKAIQFKVPVQNWQEALYVTSKPLLNMGIIKKSYIDRMIASVnQYGPYIvIAPGIALGHARPG--NDIRHTAIALATLDPAINFGNKINDPVDIVIILAASNnNDHLELLQKLVKFLNNSQNLAYLKSSSSDSDADCISRL-- +>tr|X5DVI6|X5DVI6_9CORY Putative PTS system, IIA component OS=Corynebacterium glyciniphilum AJ 3170 GN=CGLY_11135 PE=4 SV=1 +---VAEDHIVLRDAVQGWRDAIEIVGGILVDKGNATRDYVDAMIASIaGpNGTYIdLGAGIALAHARPE--NGVQSTGLSVLHLGEPVLLADDPTHPVTVFIALAAVDsRGHLDVMKNLARVLTDEDLRQTLLNATTSADIVSALSP-- +>tr|A0A0F0C3J8|A0A0F0C3J8_9CLOT Ascorbate-specific phosphotransferase enzyme IIA component OS=Clostridium sp. FS41 GN=ulaC PE=4 SV=1 +---VSLDDIELNVSAADWQDAVIKSGTILLNNGYVTREYVNAMVQTVkNLGPYIvVAPGLAMPHARST--NGVIKSGISIMTLSQPVEFGNESNDPVYLLIGLAGSNdDLHLKIMQAIATIFEDDRMLERITACDRREMVARIFND-- +>tr|A0A1N6Q7Y8|A0A1N6Q7Y8_9SPIO PTS system, ascorbate-specific IIA component OS=Spirochaeta americana GN=SAMN05920897_10448 PE=4 SV=1 +---IATRTIAVRQATSDWEAAVRLGGEMMKSAGLVEQSYIDAMVDNHkKIGPYYvLAPGIAMPHAKPE--EGVRKTGYAVVTLAQPVSFGDPENDPVDLLIFAGAISrEDHNEEVVPQVAELCDSESYvARLRGAPTVEAAISVLRD-- +>tr|A0A1R4FWA5|A0A1R4FWA5_9ACTO PTS system, mannitol-specific IIA component OS=Actinomycetales bacterium JB111 GN=CZ771_11535 PE=4 SV=1 +---IIDQGVMWNVSAESWQELTLGVGQRLIELGLCDERYPDAMVQNVvKNGPYLvIAPGLALLHARPD--EGATKNGLVMGTSANSIEFGHSTNDPVTLFIGLTATGdMEHLDMLQEVAQMLAAPGALDGLRSATSESDFVAKLRA-- +>tr|A0A1R4FDF3|A0A1R4FDF3_9MICO PTS system, IIA component OS=Agrococcus casei LMG 22410 GN=CZ674_04000 PE=4 SV=1 +---VATATYASGVYAPSWEEAVRAAGLDLVNAHAVGPAYIDEMLQIIdNYGPYCvVAPGVAVPHANAS--SLVRKDGVAVLALEEPVRFGHPHNDPVRLIVGIAATTaKRHITMLAGLAKSLDAPGVVNQIVAAGSRKEALELLGV-- +>tr|A0A1R4EW33|A0A1R4EW33_9MICO PTS system, IIA component OS=Gulosibacter sp. 10 GN=FM112_00320 PE=4 SV=1 +---FNTGMVRRGLPAAGWREAVTAAGDLLVDGRCVRRGYTEKLVDIIeRFGPYMvIAPGLALVHAQPS--ADSLQRGISAVTVPDGVDFGHSHYDPVSLVIGLSTTNaSEHLDIVAGIANDLEGSEGLvARAAAAESDEALVELVRA-- +>tr|S4ZXM2|S4ZXM2_LACCA PTS system, fructose-specific IIA component OS=Lactobacillus casei LOCK919 GN=LOCK919_2995 PE=4 SV=1 +---VIGNNINLASKAQTKDEALQELCHMLKQNGTVSdeRLFYQDVLKREKIGATGMENGIAIPHGESD---AANKVAIAVLKTRHALAWESLDDQPIRLVFLLVVpttgRDVLHLKLLSHLSAALTHREVQEKLLHENDADQFKKILE--- +>tr|E0P0N9|E0P0N9_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Selenomonas sp. oral taxon 149 str. 67H29BP GN=ptsN PE +---HENQIVFLEDSFSSKNEVIHHLTH--RENSAVRdaDQYERDVLEREASFATYTIDGVAMPHAKSE---GVSTPFVAFARLKTPVRWGTEEGEDARMVFLIGVpkvgstaDNNLHLKILAALSKKLIHDEFRAQLSTANSTKDIYALLQ--- +>tr|A0A1E9J214|A0A1E9J214_9FUSO PTS fructose transporter subunit IIB OS=Fusobacterium sp. HMSC073F01 GN=HMPREF2747_10990 PE=4 SV=1 +---INANRILLNKTMKNKNEAIKEMAKLFVEDGVVDnyDEYLKSLMDREAIAETAVGYEVGLPHGKST---AVKYPAVAFARLSKDIMWSEEEQETAKFIFMLAIptaaAGNEHINILVNLSKKILDDDFRELLSKSNDVEEIMNAIN--- +>tr|A0A1F8JTY3|A0A1F8JTY3_9BACT Uncharacterized protein OS=Chlamydiae bacterium RIFCSPLOWO2_01_FULL_28_7 GN=A2888_00675 PE=4 SV=1 +---MDVNNI-VFLTKKNRNDVISELIENLYKTQKIKnkNIFFDNIIKREKLFSTGIGMGVAIPHTKNG---DFENFFIAIGIQkKNKINWLSIDKIAVNIVFMIAGpenKQSEYLKILSKLTSLIKNESFKNKLLKFEFKEDIFAFFD--- +>tr|A0A1K2I8K0|A0A1K2I8K0_9LACO PTS system, fructose-specific IIA component OS=Lactobacillus rennini GN=LREN565_1816 PE=4 SV=1 +---FDLQNIFTDVTVTGNKNAALQKMAELFASKNQLdaKALLKGFEAREQESTTGFGSGVAIPHTKIA---GLKQPLVGMTTFTQPINWESLDEQPVTIAIALLMpiadSSKAHLSVLAKFARKLMDEQFVADLQAARHQAQSLyQVVT--- +>tr|A0A1L8P610|A0A1L8P610_9LACT Uncharacterized protein OS=Alkalibacterium sp. 20 GN=AX762_11660 PE=4 SV=1 +---ETKVILDLNNKYTDKKSFFAELCEVIHNEMDEKvlaITIKEALEEREKVVTTGFGNELAIPHGKVE---GLISPYLFFVRVKNPIEWQAMDDEKVKFIFVILVpsddKDNNHLKVLSILSYNLMDSEYQKMIKTVKDEEEAKNIIE--- +>tr|D8ID52|D8ID52_BRAP9 Putative PTS IIA-like nitrogen-regulatory protein, PtsN OS=Brachyspira pilosicoli (strain ATCC BAA-1826 / 95/1000) GN=ptsN PE=4 +-----LDSVKIIDNTNNWQDAVEECFKPLLKKEYINKEYIQKVIDSGKELNFYylIGKHLAMPHAKRE--SGVFKNGITLLVVKNGVNFENHSNNPIYCLIGLAAVDnDSHIEIMSDILDIFGSEEDGVvanELRNMNSEeeii----NYlLNK-- +>tr|R6DK77|R6DK77_9CLOT Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Clostridium sp. CAG:242 GN=BN558_01795 PE=4 SV=1 +-----KQSIACAVSAQNWEEASRQAAQILIDKGAIRSEYLTRMMEKLEKERSYmvLTSGVAVIHARPG--EDVCKNSISLLTLKQPVEFGNANYDPVSVVFMLAATDdNSHIRLMMAVAQKLSQPDIKEKMLAAKEIeelw----TLmQD--- +>tr|A0A0E3Z9F0|A0A0E3Z9F0_9FUSO Uncharacterized protein OS=Sneathia amnii GN=VC03_00290 PE=4 SV=1 +-----KELINFNIQARNWEDALENTCNILEKNGYIEHKYINKLINITKEIGPYyiITSNVGIPHLRPD--EGVIKSGLAFFKLRNKVDFLG---NKIQYLIYILALNsNEHIDKIQSITSILEDKNLFESLNNNKFNiDEFIKYINN-- +>tr|A0A1B3SM11|A0A1B3SM11_9MOLU PTS system, ascorbate-specific IIA component OS=Spiroplasma helicoides GN=sgaA PE=4 SV=1 +-----KENFLYVPEVKDWKELLKIGTSYLKEKNIVTNKYHEALLKEIDKLGFYfiISKEIALVHIAPG--GENLKTNLLFINLGKEINFSSDERHKVKHCFFLTAINsQDHIEILSNFAKEMSNKQFVKELDGVKDYenyl----SISKQ-- +>tr|A0A1W1X2C8|A0A1W1X2C8_9MOLU PTS system, ascorbate-specific IIA component OS=Mycoplasma agassizii GN=SAMN02745179_00613 PE=4 SV=1 +-----KDLIKISDQKLNWIEAIKEGVGLLEKKKYCQMSYADSIIESTNKYGPYyvISPLLALAHALPE--GNVSKVGLSLVLYKNIVNFSDKNEHQVQLLFTLCTTSpNDHIEMLQKFVTvFNENKDLTNQIINATTVdeih----QLLKE-- +>tr|M5DZY0|M5DZY0_9FIRM Uncharacterized protein OS=Halanaerobium saccharolyticum subsp. saccharolyticum DSM 6643 GN=HSACCH_00965 PE=4 SV=1 +---LKQNQIKIIDEEIDWKEAIKQAGKLLLDKDLIEAKYIRRMIEIVEDKGPYiaIAPEICLAHAGIE--DGVNESAISLLVIRNGIKLGH-QFDPIKFIFVLAPINKKgHMPALTDIMDFANNSELMAKIAAAKSEAAAYKILE--- +>tr|S6EI85|S6EI85_9CLOT Putative PTS modulated transcriptional regulator,MtlR family OS=Clostridium chauvoei JF4335 GN=CCH01_001930 PE=4 SV=1 +---FSINNINLSIEESDWREAIRKSAKPLLEDGVINKAYIDDMVKNIEDLGPYivVDDGIAIPHAKPG--KNVKGFGFTITTFKEPISILN--KDGVKVFFTMATENEKdHIDIITQLMKLVEDEDFIELLKVSSNPVKVFQRVR--- +>tr|A0A1T4K7D6|A0A1T4K7D6_9FUSO Transcriptional antiterminator OS=Cetobacterium ceti GN=SAMN02745174_00370 PE=4 SV=1 +---LDKEGIYLNLEGMSWEESVRTAGEILLKRGSIKKEYISEMINKINIFGPYmvTDDKLALPHSKND--NTVKKTDMVLLTFKENIIF--PENTPVKTILAFSSVDGIeHLNALSQFMDLINNYRFLEKIKSGLDSKKIIDLIK--- +>tr|A0A1U6TNA6|A0A1U6TNA6_9MYCO Probable licABCH operon regulator OS=Mycobacterium abscessus subsp. abscessus GN=licR_4 PE=4 SV=1 +---WNKGTCLSESL-KYGLKVLKQQGSILNDKE-----VFAALEAR-------aEIGGLAIPETTLA--LYhtsnnqIEKPSFNIIDLPEMVSLRAmnGANEMVKRVLLLLAPLNAsseVMEVLSFLsASIIESERSIEVF-NKGNKEELLNFIS--- +>tr|A0A1W1XNX2|A0A1W1XNX2_9CLOT Transcriptional antiterminator, BglG family OS=Clostridium acidisoli DSM 12555 GN=SAMN02745134_02524 PE=4 SV=1 +---FFTEICATNVNGiiQELLEEQVKYGVIDMKT---SDGIKVMLVNR-------dKLGTIILPNKKFV--IYhcvssdIKEPMITVGKLKIPIKLINliDKKELIYTAFLMVAPLNKkdSLEVIGDLsSSIIEQVDFIDRLNESKNAEECRKIIE--- +>tr|A0A1Y4HN69|A0A1Y4HN69_9ACTN Uncharacterized protein OS=Collinsella sp. An2 GN=B5F33_04560 PE=4 SV=1 +---L-LGNVRLDKEAHSWQEAVRVSGEPLVESGAIDSGYIDLVVANITELGPYvvISQGVALPHAAGA--GHVHRTAMSCVRLAEPVAFGAADRDPVRFVFMLATVDATsHMRALVHLAELLTTPEFMQTLAETDNVQQLMDFVT--- +>tr|A0A1Q9HEQ3|A0A1Q9HEQ3_9VIBR Uncharacterized protein OS=Vibrio panuliri GN=BIY22_08585 PE=4 SV=1 +-----GKRIKYSDVKLSWDDALEQSIAMLQHDGIVNQHYIEAIRSVTDEIGPYyiLTDDLAMPHARPdE--GVIAGqGGLSLLICHSPVRFDQ-EHSAVRAFIGLAAGdSEQHVLTISNLMNWLDSDDAMEKLLSVQNQSELERLVES-- +>tr|C4XFJ8|C4XFJ8_MYCFP Putative uncharacterized protein OS=Mycoplasma fermentans (strain ATCC 19989 / NBRC 14854 / NCTC 10117 / PG18) GN=MBIO_0655 PE= +----VNDSIVPHVDVKDWKDAIKKACLPLEKAKVINSKYYDCILESiKKHGPYFiLVDGLAMPHASAT-KDAVFGNGFSLITLKKPIKFEGDE-REVKILMGLAAKDgETHTSvAIPQIIAVFEDPQNIEKIAQAKTKEEIINIIKG-- +>tr|B0P4U7|B0P4U7_9CLOT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Clostridium sp. SS2/1 GN=CLOSS21_02803 PE=4 SV=1 +----DMICTRVIEEVKDYQSAIKMTCDILEEKGAVNHTYYQAILDNiEKYGGYFyLGKGICMPHART--EDGAIKSGMCVLMVKNKVRFFNNQ---VRVFITIAAKGeMEHFKNLHRIANFCNDEEKMKRLEEIKDEKELLELIGE-- +>tr|A0A1B7HJN4|A0A1B7HJN4_9ENTR PTS system ascorbate-specific IIA component OS=Buttiauxella noackiae ATCC 51607 GN=M979_3241 PE=4 SV=1 +----EAQAIQVGVRETDWKKVIRLAAQPLVDNGYILPSYYQAVINNtLEHGAYYvFEEGVAMPHARP--ECGVMKNCFSLVLLDEPIAFAD-S-EKADIVIMFAACDsNGHIEeGIRAIVNLLGDDDVMAKLRRAKGKEEVIAIL---- +>tr|A0A1C5W7K5|A0A1C5W7K5_9FIRM Mannitol-specific cryptic phosphotransferase enzyme IIA component OS=uncultured Eubacterium sp. GN=cmtB PE=4 SV=1 +----KKENIVLKRHAKDWKEAVHISLEKLVEGGYCTDQYEQGVLKNtAEYGPYYvLTEEFALVHCND--FASVNETQMAVTTLDEAIKFSEDG-YDVRILVALVAVDgDKHLDGIRAISNIFADEDKVQEIIDATEPEKVLQMFIE-- +>tr|A0A0Q4NI99|A0A0Q4NI99_9ENTR PTS fructose transporter subunit IIA OS=Erwinia sp. Leaf53 GN=ASF13_18005 PE=4 SV=1 +----ARENIFLNQAFTSKQEIFRFLAGHAVAQGWAEsaAAIEADLWQREQQYSTGFENQIAIPHAKTAN---VSQAGVIFIRLAQPIEWESLDDQPVQIIFGLLVPesgaKVLHLQIINSLASQIVEDDFRQFLFIAESENALFEFMKS-- +>tr|R2R040|R2R040_9ENTE PTS system, fructose subfamily, IIA component OS=Enterococcus raffinosus ATCC 49464 GN=UAK_02653 PE=4 SV=1 +----VNDLIVFDESIRSKKELFEKLGQLLEEEQRVSkaKKVIKDLYRREEETSTGIEDGFGIPHAKSKA---VLQPTICFAHTGKITDYVGLDGRNIEWVFAILVPqktAYIHLEILSKLSRKLMNESFRTQLKNAGSPMEVLEIMSK-- +>tr|H9ULG8|H9ULG8_SPIAZ Phosphotransferase system mannitol/fructose-specifc IIA component (Ntr-type) OS=Spirochaeta africana (strain ATCC 700263 / DSM +----DESLVRPGMTAENKDDVVDQMLQMLAATGKVGdvAAAREALIANEQRTATGMQHGIAIPHAKTEA---VDELLACVAVTTKPIDCSAVDGKPSRIFIMTLSPpdrvG-PHIRFLSEIGRILKSRKVRDRVLKAATPAELLQALGG-- +>tr|B1BZF5|B1BZF5_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=[Clostridium] spiroforme DSM 1552 GN=CLOSPI_00332 PE=4 +----DKECVVFDIPDTTKDNVIKTLISKLDKVGCISnvEEFYKNVLDREEICATAIGNEMGLPHGKTSN---VLRPSICFGRLLNPVIWNEKTGEKVKYVILIAVPeknsSDVHMKIISSLARKLMHTEYRNILLNGTQEEVFDFLNAT-- +>tr|A0A1G2ZJ68|A0A1G2ZJ68_9BACT Uncharacterized protein OS=Planctomycetes bacterium RBG_16_43_13 GN=A2W23_08870 PE=4 SV=1 +----SEKVILTNFKAGTKLDAVGRLVDVIIASGDIPkhhrQAVLDALIARENICSTGMEHGVAIPHATVDV---LERPAAAVAVSLEGVPFQSADGKNATIIVLLIITrkdvK-HNVRTLAGIARLLNYEDTRQHLLVAKTPSAILDVIRE-- +>tr|A0A1V5G8W5|A0A1V5G8W5_9BACT PTS system fructose-specific EIIABC component OS=candidate division BRC1 bacterium ADurb.BinA364 GN=fruA_1 PE=4 SV=1 +----IERAPLVELTAKTKEEALRQLAEAFRGEPKVAnlDRFIEAIFAREKVISTGIGIGVAVPHVKIPE---VSDFVLAFGRHREGLDFDSLDDQPVHLLAMIGASeaqaG-EFLKMLARLVRTFRARDVRRKLMQAENAEAFRAVLRE-- +>tr|A0A1V6GIS4|A0A1V6GIS4_9BACT PTS system fructose-specific EIIABC component OS=Verrucomicrobia bacterium ADurb.Bin070 GN=fruA_2 PE=4 SV=1 +----QKSLVCLNATESEGQEVITALIDKAVHAGLLPaehrDTAVRAVLNREMSASTALPDGIALPHGRIEC---VRDIICMLGVHPAGIAFGAPDNQPTHVFVLLLVPatvaC-NHIHFLAKLSRRLMEASVRNELLAARTRDDVMRTILS-- +>tr|D6XZQ2|D6XZQ2_BACIE Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10) GN +---LHESRIQWEQKAGDWKDAIKKSAAPLLNDGDINETYVEAMIRNiEELGPYIlIAPDVALPHARPE--HGVEKAGFTVTVFKEPVPFPKGTDQSvseARVFVCLAAVdSESHLGLLQQISGLIEDRSLIEALLQASSEADVHKALSG-- +>tr|A0A1C0ADK1|A0A1C0ADK1_9FIRM Transcriptional regulator OS=Orenia metallireducens GN=U472_00180 PE=4 SV=1 +---YLKGNINFLDEVSSWEESIKVAAKPLLKKGFITDKYIQSMIKNvYDNGPYMvIVPRIAMPHAQDK--EGVIKTGISFLKLKKPVLYPEGKEV--NISVVLAAEdNSGHLELIADLSSILADEEVRNKFENVESEEELIKIIKT-- +>tr|A0A1U7APA6|A0A1U7APA6_LISMN PTS sugar transporter subunit IIA OS=Listeria monocytogenes GN=BWI22_14415 PE=4 SV=1 +---LNKELVNLHGTAKNADEAIVQAGELLVNAGYVSEQYVEKMVESyHENGAYFvIAPQIAIPHARPT--DGVENSAVSLVVLKDGVNFGHAANDPVRLVFGLAATsSEAHLKVIQKIVSLLSNNDNIEKMIHSEDYQAIGELVEG-- +>tr|F5T9Y6|F5T9Y6_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Oribacterium sp. oral taxon 108 str. F0425 GN=HMPREF91 +--------YSFINGKDvSWQEAVRLSALPLVEDGSVDSDYYKQIVACIEKHGPYivMEHNIAMPHTTENP-IGAHRTAVGLMICENKIDFGqdTdGEKKEANLLFTLSAVNTdEHMENIAQLMDVFMNYDLIEALGKCHSAEEILEAMKK-- +>tr|G2IE46|G2IE46_9CLOT PTS system, IIA component OS=Candidatus Arthromitus sp. SFB-rat-Yit GN=RATSFB_0858 PE=4 SV=1 +--------YSFHESFDDWREAIKASYVPFLKNGIVNDFYVDAVIKSVEEYGPYivLMKDIAMPHSNVNE-DWCKETSIAFMKVKKPVIFDPnDSEKQARLFFSLSIRDNeEHIKNLQGLMEVLENEELVSELLEADNEQEFRKIVDK-- +>tr|C8NEQ4|C8NEQ4_9LACT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Granulicatella adiacens ATCC 49175 GN=HMPREF0444_0399 +--------FSFQKGSLSWEEAIKKACQPLLEQKIIEPEYPGYIISNVHEFGPYivIAPEICIPHAQEGK--GVNDTAVAFMNIEEAVDFGPGADYQPHLFFVLASTDNeKHLNNLSELVTLLDDESIINAFVEARSKEDLENILKG-- +>tr|A0A1Q6MWC4|A0A1Q6MWC4_9FIRM Uncharacterized protein OS=Clostridiales bacterium 42_27 GN=BHV90_19355 PE=4 SV=1 +--------FDVYSGF-dTWEEAVKTASSPLIRQGLVEPDYADSIIENVAENGPYifIAPHICMPHSKRT--DLVRQAAVSFVKINRPVCYDesD-PEMGAELFFAIAVKELnAHLDVMMDLADVFDDEETVRALLDAKTKEDFDKLLG--- +>tr|G7M9S6|G7M9S6_9CLOT Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Clostridium sp. DL-VIII GN=CDLVIII_4738 PE=4 SV=1 +----TINTVEFNLNLKTQGEVLEKITDILFKDNRIEdkKETLKGYIDRENECTTGIGFGLAIPHCKVE---SVIKPTIVCLKLNQAIDWNSLDEEPVNIIIGLAIPkkyeGTLHLEILGKLASNLMEDDFKRTLFNINDKNKLVTFLQE-- +>tr|I7KTP2|I7KTP2_9CLOT PTS system, fructose-specific IIA component OS=Caloramator australicus RC3 GN=CAAU_1104 PE=4 SV=1 +----NENLIVTGLEASNKEETIKKLIDMLEKEERLIsrEKFFEDVLFREQLCSTYVGQGVAIPHGKTD---AVKKTSVAIGKLAKPIEWDEKENNYVNIVFLLAVQdkdaDNQHLRILANIATKLMEKDFIDNLTSINDKDGILALFRE-- +>tr|E3DMB1|E3DMB1_HALPG Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Halanaerobium praevalens (strain ATCC 33744 / DSM 2228 / GSL) GN=Hpra +----SEDLINLDFNPVNKEDALSKMVQMFKKENKIKseTDFLNKIFKREKEGSTGFGRQIAVPHGKSK---TVKELSLAVARVKNGLKYNSLDGQKVKLIFMVADYegySPQYLKLVSTLVSLLRDNNFRTKLIEAKNKNEFIDLFRK-- +>tr|W6A8C9|W6A8C9_9MOLU PTS system fructose-specific IIA component OS=Spiroplasma culicicola AES-1 GN=fruB PE=4 SV=1 +----NINSIIIDTDFSTQEQVFSHLSKYFVKNSYCTnyEEIKVGFFEREKEGSTAFTDGIGIPHSKVN---SIIQPGIYVIKNKNGINWDSLDGKETNFFIALAIPnldsNTLHLKMLSSVARKLVDKEFKKNILNAKTKEEIFELLSL-- +>tr|A0A0R2LLZ1|A0A0R2LLZ1_9LACO Uncharacterized protein OS=Lactobacillus paucivorans GN=IV54_GL000510 PE=4 SV=1 +----NPNNISLHLECSDQEALLQKMTHWLFQSHAITneAGFLEDVDYREMLGMTGIGNEVAVPHGS-N---CVAYPTVAIATLQAPIAWKSIDDAPVRLVLLFAEPdeptpDQAHNTLLTKMIRKLSNDETLYAVKQAATVDEIVNALKE-- +>tr|R7PMI9|R7PMI9_9CLOT Uncharacterized protein OS=Clostridium clostridioforme CAG:511 GN=BN688_00912 PE=4 SV=1 +----NENAVAVNVKAQNKEEVFECVCDLLLKDGSITskEEFKQDLYIRESQGKTGIGDGIAIPHGKSL---AVKRNCISVLKLERPIQWETLDGRPAQMFIIFAINqrdkDDYFLRLMASVAKKLAQEGTCGKLMGSSTKEDILEAFY--- +>tr|A0A1R1LCC1|A0A1R1LCC1_9MICC Uncharacterized protein OS=Tersicoccus phoenicis GN=BKD30_06445 PE=4 SV=1 +----NPRMVRVGLPGQTKAEVFRSMATLFVETGKVTdlERFVEDLQTRERSISTGVGRGLAIPHGKSE---AVSTATYAIATLRDPFLWDEDDEETTKLVVMLGVPanepATTHLRLLSEFATALMDDEFRAELINAEDEADIRSALAS-- +>tr|A0A1I5TU97|A0A1I5TU97_9GAMM PTS system, fructose-specific IIA component OS=Enterovibrio norvegicus DSM 15893 GN=SAMN03084138_03341 PE=4 SV=1 +----NVEHILTDAHSTSQQQAFQFIAEHAHQLGYIDsvDGFARGLQAREAHDSTGFLGGMAVPHCKSA---HVKTPAIFVVHFANPIEWDTMDDEPVTTAVSLAIPesgAEESLMMLTKLSRAMMKPDIRNTLQQNDTQAILDTIQHV-- +>tr|A0A069ADX8|A0A069ADX8_CLODI EIIBCA-Man OS=Clostridioides difficile GN=manP_6 PE=4 SV=1 +----TEESIILDLKSTTKEGIIQELVDKLYDTGSITlkSKFIKALKHREKIGSTSIGYQMAMPHGKTK---YVKKASVVIGKSKKGVDWPSIDGLPVKVIIMFAMPqsgGNEDMILISKIAYILGGKNIGERLLNAHTKKEILDIFYE-- +>tr|A0A1V3NT24|A0A1V3NT24_ENTCA PTS sugar transporter OS=Enterococcus casseliflavus GN=BZK37_00465 PE=4 SV=1 +----TPDLILLNSDLADQDEVIRHIVEAAEFVGYVEdaDELYQAVRKRESEVPTAIGYDIAIPHGKTE---AVLHPFIAFLRVNKAFQWTKENEEMVRLVFLIGVPqnseGKMHLKFISQLSKKLLDDDFRDKLLSETDKNKIYEQLSS-- +>tr|A0A1W9VGW4|A0A1W9VGW4_9SPIO Uncharacterized protein OS=Spirochaetaceae bacterium 4572_59 GN=B6241_00715 PE=4 SV=1 +----KKEC-CFRLNENKKTEVLIEMMECIHQKGFIEdlENLKKEIFYREQLMSTGVGMGIGIPHVRFK---GVEKPLIAIGIKeKGVVDYDSIDNEDIKIIVMIMVGenqHKEHIRLLSQVIGRMKDAGDREKLIHASDSEEIYNLLTG-- +>tr|A0A123T4K4|A0A123T4K4_STRSU Putative PTS system, fructose-specific IIA component OS=Streptococcus suis GN=manP PE=4 SV=1 +----TLQQIFFQ-HFLEKEEVL---SEIAILAEKLGiasGNIYDELKKREEEYSTAIGHGLAIPHAKTDL---IHSPAILFFKLEQVIDWSGDEV---CMIIAILTPrseAGIHLSILSRLSRKLMHREFRERLEAAQTQQEVFDLFR--- +>tr|A0A1F7RL77|A0A1F7RL77_9BACT Uncharacterized protein OS=Candidatus Schekmanbacteria bacterium GWA2_38_11 GN=A2042_03675 PE=4 SV=1 +----LFEDQVYLDLK--AKNSFGCFLEmlrCLEDSKIIKdkAPILTALMTREELEPTSVGCNIAFPHARTFQ---LEKPILIIGRSKEGIDFYSRDGKKINFVFMLLFPrkfNELYLELVGEIMRFLSNSALLDCLQKINTPEELITLIK--- +>tr|A0A1C6HDE7|A0A1C6HDE7_9CLOT EIIABC-Fru OS=uncultured Clostridium sp. GN=fruA PE=4 SV=1 +----DENTVNLELEANDRDSVIRELAKMLNHNGLIQdlECFIQSVLEREKICSTYSTSELAVPHGISPS---VRKAGLCFGRLTSAIDWDGDQETPVRYVFLIAIPqaedeavINRHLEMISSIAVSALqednlekwgkvkdAEEFLATLETADGRG---------- +>tr|A0A1C0BWB0|A0A1C0BWB0_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium MTC7 GN=A4S06_08765 PE=4 SV=1 +----NNQTVFLNVEGSTKEAILQAVTQQLETSGYVKnaKHAYNDIMKREAEISTGFVSGIAIPHTQSEA---VEKTSISIIKPVNSLSWETMDDSDVDLIFLICVPlngLDEHLKILASLAEMLMDEDVIDALHQIENEDEIVDYIR--- +>tr|A0A1F5RLG1|A0A1F5RLG1_9BACT Uncharacterized protein OS=Candidatus Eisenbacteria bacterium RBG_16_71_46 GN=A2W00_06915 PE=4 SV=1 +----DPSLFVPDLRTRRKESVLGEMIARA-HlAGAVRlpELLRETLVLRERAGSTAVGKGVAVPHARSLS---VSEPHLVVARSRRGLAWTPGDPQPVTLVLLALSPaevPAEGHLDFVARVVGATrlQR-NRQKLLEAESFDAVAAVLR--- +>tr|A0A1M6FRC1|A0A1M6FRC1_9FIRM PTS system, nitrogen regulatory IIA component OS=Propionispora hippei DSM 15287 GN=SAMN02745170_01532 PE=4 SV=1 +----ALDCIVLHVEAKHKEEVWELLAERLQHSGVIStaEQFVEDVAARESMGTTGVGHGVSIPHAKSAA---VDRAGLAIARLATPVDVNSLDGTKADLFFMVAAPldgIDLNLQMLSTIARMIRHDSFLAALRTAPTAEEMLRIIG--- +>tr|A0A1Q7V0D1|A0A1Q7V0D1_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium 13_1_20CM_3_54_17 GN=AUG52_05015 PE=4 SV=1 +----DEKRVILGLRSRKMPNALREIIDLLAQNGKIDnpEAFFEKVLAREQAHPSVVENSAVFPHARTDL---VDEIVVGIGRSRAGIPFGH-NGVRARLIFVIGVPerlVNDYLICVGTLVRLVRDDATRSALLHAQTPRELIDTLT--- +>tr|A0A1V6FHG8|A0A1V6FHG8_9BACT PTS system fructose-specific EIIABC component OS=Lentisphaerae bacterium ADurb.Bin082 GN=fruA_2 PE=4 SV=1 +----SPSLVKLDVKAQDKEELFEEMVQLFVDNGQITdrESAVATLLEREAKMTTGISRWLGLPHGKLAE---ATGILIAIGVSKKGIDYDSLDGAPVYVVITIFAEmgnPGPHIRALAEISRIFAIHGVIDKIRQAKTPQQVIEIIK--- +>tr|A0A1V5UCN0|A0A1V5UCN0_9BACT Heat-responsive suppressor HrsA OS=bacterium ADurb.Bin243 GN=hrsA PE=4 SV=1 +----DKRNIFVNFCAADKHD---AISKligIMDPGEAISdkADYMASVFEREELGTTGLGDSVAMPHGKSGA---VKKMSVALAKLSQPMDFESIDNSPVSYIFLIASPlnaDTLYIKVMASIIRSVKIHRICEKMNTLESPGEIYEMLL--- +>tr|A0A1V5S959|A0A1V5S959_9BACT PTS system mannose-specific EIIBCA component OS=Candidatus Omnitrophica bacterium ADurb.Bin292 GN=manP PE=4 SV=1 +----KENDLVAGLKASDFKDALTKLVGMIPDwRLGPKmkKDVFQLLVDCERIGTTAIGGGIALPHCLSED---VREPIVMFGVSPDGLVCPSLDGYPVHFIFMLLLPkdeQAELRKRSVLQSAKWMlsDRSLRDELLDARSSADIYDCLA--- +>tr|A0A1Y1RUZ4|A0A1Y1RUZ4_9SPIO Uncharacterized protein OS=Candidatus Marispirochaeta sp. JC444 GN=B4O97_15025 PE=4 SV=1 +----PPSSVLVPLRAETKQEAFDELFAGISMlRTLD-riHGLKEAVLRRELEGNTGIGHGVAMAHGKLQS---LTDIFLCLGISMHGIEYGSYDGEPVRLLFVAANPpsmQGVYLHMLAVLSRYLHLAAFRERIINSEGHI--ARVLL--- +>tr|A0A1D8SGQ0|A0A1D8SGQ0_VIBMI PTS ascorbate transporter subunit IIA OS=Vibrio mimicus GN=VM_17780 PE=4 SV=1 +---ITEKHVALNIATDSPQDAISQVGQLMVNNGLVEPSYIEGMLHIyEEFGPYWvLTHGLAMPHARPE--DGAIESGFVIMTLEQPLNFGHEEHDPVSIVIGMSATdQNKHIENIQQLTQVLNNKQKINMIMQAKEYPEVIEIMNR-- +>tr|A0A1R4B7V3|A0A1R4B7V3_9VIBR Ascorbate-specific phosphotransferase enzyme IIA component OS=Vibrio palustris GN=ulaC PE=4 SV=1 +---INESNIVIStAENLSVDAALDITCSTLIEQGKVETRYLEAIKAKhKEIGAFYvLAPRIAMPHARPE--EGVNEASLQVTVFKHGVDLESEDNGDVFFSVTLAAKdADNHIQTIVALSELFQNEQDIEAIIASESKREIQAILNK-- +>tr|A0A0E3UTL9|A0A0E3UTL9_9FUSO PTS fructose transporter subunit IIC OS=Sneathia amnii GN=VC03_01640 PE=4 SV=1 +----NKKLFIPELGSADKKDVIEKMVDKLYENDCITskEEFLKEVLKREEVAHTAFEGGVATPHAKS--S-VVKKASVVVGISHDGVDFSDGEEEKSKLFFLIAVpvdNPNLHIDVLAKLAGLIEDEGRINNILNADNFEEVLKNIHE-- +>tr|T4P8S7|T4P8S7_CLODI PTS system fructose-specific EIIABC component OS=Clostridioides difficile P28 GN=QSI_0017 PE=4 SV=1 +----ERKNIIITKNIQNKEQLFHYLAEYMVSQKEIDakhqEAFEQALWSREQLSVTGVGNDVAIPHVQK--E-FITRPIVIFLKSETPIAYESIEGDSVRLIFMIAVpehASAKHLNFLAELSRKLMDDDFRKHLLEASDVDALYHIISE-- +>tr|A0A1Q6T4Q0|A0A1Q6T4Q0_9FIRM Uncharacterized protein OS=Subdoligranulum sp. 60_17 GN=BHW54_03670 PE=4 SV=1 +----RPDCVALRQRADSLTGAVQQMVTLLNGTDNLTdtAVFAADVRARLALGGVCVGNGLAIPHAKS--T-AVRQLQLAALTLDPPLPCDTPDGKPLDLLVMIAApaeANDLHVQVLAELATLFLDTDFCACLRESETPEAFCRAISA-- +>tr|A0A1L3RGE1|A0A1L3RGE1_9PROT PTS system, fructose-specific IIBC component OS=Granulibacter bethesdensis GN=GbCGDNIH6_0410 PE=4 SV=1 +--------------PYRGSVAVMTILAIIDGQARRTH----ALLAAEALRKA----------ASNRNRSI--EIDLRVVGSASPEPDTRMI-----STLLLVGeaes-DSTHLDIADKLSAFPKHKTTLDTILA--DADLVLDNIGD-- +>tr|A0A1N6IJU9|A0A1N6IJU9_9LACT PTS system D-fructose-specific IIB component (F1P-forming), Frc family /PTS system D-fructose-specific IIC component (F1P-formi +----NNKKIFLDVDVETKTDLFKFAANQLYDLNLVSnkEKFVKALLNREELSPTGMGDNWAIPHGQDDS---VKAASVLYIRTKKPIVYESLEGNSADKFFFIAVpssTSSDHVKILSKIATLLMEDEFKKSMSNIKNKEDIMTLISN-- +>tr|A0A1Q8F267|A0A1Q8F267_9GAMM PTS 2-O-a-mannosyl-D-glycerate transporter subunit IIABC OS=Aeromonas veronii GN=BTN33_16205 PE=4 SV=1 +----GPHLITLQTRFADRDAAIHALADRLDQAGKLHdkAAFLAAVMAREAQGPTALGEGLAVPHGKCDA---VREAAFAVATLSEKLGWEGIDGPePVNLIFMLAIptdqAGSTHMQLLTTLTTALVDDDTREAVLAAKSAEQLMALLDG-- +>tr|A0A0T9AH71|A0A0T9AH71_STREE Transcriptional regulator, BglG family OS=Streptococcus pneumoniae GN=licR_3 PE=4 SV=1 +-----KETYQVSSQKLGWKEAIRLSNTIXXXXPTL---FKELIIIRdFHFCFFfLV------------------------------------------------------------------------------------------- +>tr|E7MN36|E7MN36_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Solobacterium moorei F0204 GN=HMPREF9430_00954 PE=4 SV +-----KELTIFTdKVYHDKYEAIEDIAHL--PNEFVNnsDEYAKAVIARENVIATYIGYGIAIPHAISA---AVNQAFVIYVKFLNGCPWANEdGEDRVDHMMMIGVpadkGSTQHLKILAELSKNLMHEDFREKFLNTKSPEESYELLK--- +>tr|A0A1M4ZU10|A0A1M4ZU10_9BACL PTS system, fructose-specific IIA component/PTS system, nitrogen regulatory IIA component OS=Seinonella peptonophila GN=SAMN054 +-----QHLIKINTTLNTKSEIFETVCKLLEADNRLLdrQLFLNDLYEREGAGATAPGYSFAIPHAKSK---GVKTASLVFIHLENEIGWTK--SEKVKYIFAIAVpyeeAKDEHLNILAMLARKMMNEDFRKELNAAKTKEEYYRLLT--- +>tr|A0A1T4MAB6|A0A1T4MAB6_9GAMM Uncharacterized protein OS=Oceanospirillum multiglobuliferum GN=BTE48_04195 PE=4 SV=1 +--RLTDIKLPLNHDE--Q---------------ALEQAILRKLAIKKQQLQA-------------------------FTIFRRGY----------------DARNKRDIQLIYTLDvEVTGEAElLAQDSSVRATPDMTYKFVAQ-- +>tr|E3G1D2|E3G1D2_ENTLS Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Enterobacter lignolyticus (strain SCF1) GN=Entcl_2887 PE=4 SV=1 +-----FSACQFRERCGTWQEAVKQACLPLEARGMVTPAYAQAIIREtEQQGPWYiLSPAFALPHARPEEGVISDKTHLSLLCLKEAVAFPEH-PEVRLVIVLAAASSIQHLEMIQRLVCWLDEAEHLSQLTRITSPAQLRSVLEV-- +>tr|A0A0U3ULG4|A0A0U3ULG4_9ENTR PTS system mannitol-specific transporter subunit IIA OS=Cedecea neteri GN=cmtB PE=4 SV=1 +-----EEKIQYLDNVANWQQAIEVAGRPLLQEGAITQDYIDTIIQQkLEIGPYFvIAPRIAMPHARPEQGAKK--LALSVLKLAQGVSFDADEnDPVDILFMFSAPDSNSHIEMISQLAEVLSDEEKMAQIFSSTNQAELSTHLLS-- +>tr|A0A242NYY9|A0A242NYY9_9GAMM Uncharacterized protein OS=Gilliamella sp. A7 GN=B6D18_09545 PE=4 SV=1 +-----EQHWQFSKENLDWKSAIQIVGNSLIENNHIEQRYITSIIDNvNEIGAYFiIADGFALPHARSENGVICEDTKFSLLKCTHPVIFPDG-EKISLLIMLAASDNNKHIDAMSDLIEWLDEDDRLDNLINVDNVDDFECLLFQ-- +>tr|A0A124INM4|A0A124INM4_9FIRM Uncharacterized protein OS=Clostridia bacterium BRH_c25 GN=APF77_00550 PE=4 SV=1 +-----EDLILLNVEGDTRDEVLNNISIALLEKGVVKKSFASALIKRENEYPTGIPigeYNVAIPHTYP---EHNNEIAVTIAVPKKPVQFYNMGNseELlKvYVIICLSFEkMDDSVKMLSSLMTFFGNEENVKAVMVCRDTSEVLKVIRS-- +>tr|W7CJ07|W7CJ07_9LIST PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN OS=Brochothrix campestris FSL F6-1037 GN=BCAMP_07350 PE=4 SV= +-----TKLLYVQQQEDSVETIFKTICKKAQQLGYTKASYFNALQTRELSYPTGLAlphCGIAIPHTDF---NHVKQPFISVMTLRKPVFFHAMDGvnGVaVQIVFVLGLTtTTAQLASLKAVMAICRSETRVEQLLHATDASELFAILTK-- +>tr|G4L9I9|G4L9I9_TETHN Putative arabitol-specific phosphotransferase system enzyme IIA component OS=Tetragenococcus halophilus (strain DSM 20338 / JCM +-----KELVFLDIESPNANELFKIIADELQNKGFVNEKYHDGLINREKDFPTGLQledYSVSIPHTDP---ETVKKDFIAIVRPRSPIMFSLMEDndKKtPvDLCFFIGLRdGKKSPLALMELISLIQNHKLILSILNEKNREKIIEKIQE-- +>tr|A0A0E3Z9S9|A0A0E3Z9S9_9FUSO Uncharacterized protein OS=Sneathia amnii GN=VC03_02315 PE=4 SV=1 +-----KEDIYFNVEAENREDLIRKMSKIFKEQGYIKDGYEESLIEREKNYPTGLNfekYFVAIPHTTY---SLINSQRIVFVRLKNEVEFGEMGTneKQlKvKVVLFLLIKkGEEQVTVLLNLMKILGDEDCYNTLEKSEDKEEVYNILVN-- +>tr|A8RYB6|A8RYB6_CLOBW Uncharacterized protein OS=Clostridium bolteae (strain ATCC BAA-613 / WAL 16351) GN=CLOBOL_05080 PE=4 SV=1 +-----NRYLVIHGFARDRYEAITMCGEALYKEGLVSEQFGTLCVEREKNYPTGLPteIPTAIPHAKD---ESITQNSVCFLKLDRPVSFKRMDDdtqDVsTDMIFNLAIKdPNEHLQALQNMMGFLNDSEALLKCKSLSDEELI-EYLQE-- +>tr|A0A1C6ASB9|A0A1C6ASB9_9FIRM Pseudo-HPr OS=uncultured Flavonifractor sp. GN=fruB PE=4 SV=1 +-----SSCVQLDVKAQDWQDAIRKACRPLMNEGFVTEGYDEDVIARELQWATGLPtepVGVAIPHSLTP--QHVITAQIAACRLSQPVKFAQSGGtaddgKVdVSIIFVLALKdPKEQLSLLQKLMAAISNEEMLASLMGTSAPLEFSNIFNG-- +>tr|A0A1H1DN47|A0A1H1DN47_9ACTN PTS system IIA component, Gat family OS=Tsukamurella pulmonis GN=SAMN04489765_1800 PE=4 SV=1 +-----THDTLLDFTAEDPATVIRAVGAVLNDAGTVTPDYVEAMLDRETQYPTGLAtepVAIAVPHATAG--DAVLHSSIGFARLSPPVAFAEMGTsdgrTVdVGFVFALAVSPDEHLGTLTSLLRLAQEESDLLSEA---TVEAITAAIGR-- +>tr|A0A1C5P2R9|A0A1C5P2R9_9CLOT Putative PTS system EIIABC component OS=uncultured Clostridium sp. GN=hrsA PE=4 SV=1 +-----ENIIRIGIDAKDKDDALHKMAGLLYENQYIDdiEGFVKDVYAREAEGETGLGQGVAIPHGESK---NAQKLGVAIVTLNHPIEWETLDGGKVDTIFLFCVSSdanfaRNHMLLLSKIAARLADDDLLKQIRVASSSCEMIALLAGE- +>tr|A0A1G4FP56|A0A1G4FP56_9FIRM Putative PTS system EIIABC component OS=Sporanaerobacter sp. PP17-6a GN=hrsA PE=4 SV=1 +-----EDNILLNIKLNSKEEVINKLSDLLVNSKAVSekEGFIKDIYERESRGFTYAGDYLAIPHGWSE---YVIKPAMAIAKTDTAFAWDK-DGNLVKLVIMFVIPEntemENNLKKIGKIFSALGDTKLVKKLLKLNTKKEIIEFICSI- +>tr|A0A1Q6N4L4|A0A1Q6N4L4_9FIRM PTS sugar transporter OS=Clostridiales bacterium 42_27 GN=BHV90_14280 PE=4 SV=1 +-----DEMVILDCEPFKDkENMFDVMTAKFEEAGFVSdaKAYKDALEYRESLGPTYMGNFVAIPHGKCK---EVLKPGIGFCRCKKPFIYESSGEsGEVKYIFVLAISEnqenDYHLRVLATLAGMLAHEEFLELLEKAESYDDLIHGIKQL- +>tr|A0A1R1CUM7|A0A1R1CUM7_9BACL Uncharacterized protein OS=Paenibacillus sp. FSL H8-0548 GN=BK133_20045 PE=4 SV=1 +----SKQNIFLNLQSIPKTEAIQLAGEKLVELGYVAENYIASMHEKEKVKSTYLGNGVSTPHGSKIAKEAVVKSGVVILHFPNGIDYENGE--KVYIMIGIAAERSYHLDVLMKAATMFEMKGNADKVANATSIEEFIQRF---- +>tr|G1VV57|G1VV57_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium 2_2_44A GN=HMPREF9022_03976 PE=4 SV=1 +-----RECILPHYAAQQKEDIIQELSKRMKERNLVNADFQEAVLKREQKYPTGLLIgkrNIAIPHTEP---QYVKVPCIGIATLKKSVAFHRMDACdelVdVDVVLLLALnQAHAHMEMLSRIILMCQDEAFIEELMRAEQETDIEQIVRE-- +>tr|A0A0A6VD84|A0A0A6VD84_9BACI Uncharacterized protein OS=Bacillus ginsengihumi GN=NG54_15130 PE=4 SV=1 +-----KIIVNTRLQVGNCKEIIERLGVQMLEAGYVKDTYIEAVLQREDILPTGLKTglvNVAIPHTDV---THVNESAISMTTLNRPVKFYLMEDPsqeIdVDIVFLLAVkEPEEQVQLLKNLIAIFQNEELLAQMKDIEDENSLNQVIKA-- +>tr|A0A0U5NXP3|A0A0U5NXP3_9CLOT PTS system galactitol-specific transporter subunit IIA OS=Clostridium sp. C105KSO13 GN=BN3456_01882 PE=4 SV=1 +-----RKDTIFFiddDKEYTDKEVLHIIGKKLLDRGYVKESFGEALLEREANYPTGLAMmpyPVAIPHTDP---GHVNEPCISIVRIKQGAVFHEMVNSesiVkVNFVFCIALqVADKQTGVLQYLMQVAGDDSIMNIIKNAKNADEIYKVVSI-- +>tr|A0A0F4WKU3|A0A0F4WKU3_9CLOT Uncharacterized protein OS=Clostridium sp. IBUN22A GN=ClosIBUN22A_CONTIG144g03033 PE=4 SV=1 +-----EKDLIFKEDFVSLDQAFKCLSKKFLERGLVKQGYLEALMEREKNYPTGIDLtavfqgfpNIAIPHTES---KYCNATKVIVIKLERDIVSKDMMNPdkdLnVKYLFMILNkDGGEQSNILAKIMEFATNKENISMLAASDSLDSIYDVVNK-- +>tr|D1AKT3|D1AKT3_SEBTE Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_0214 +-----NRCIELKSNYDSYEDLITNVSRELLKYGYVKESFLENILGREKQYPTGFELggkyNIAIPHTDM---ENVLKPVIYIVVLDRPVMFKSAEDGksdIsVDIVFVISLnEKDKHIVVLEELMKIFSKNDLIEKIKNSEDKDELIRLIYE-- +>tr|A0A0B3BAI0|A0A0B3BAI0_9THEO PTS system IIA component, Gat family OS=Thermoanaerobacter sp. YS13 GN=THYS13_18260 PE=4 SV=1 +-----DVLIFTEEVEGNREEVLSHIAEILLEKGFVKKGYKESLLEREKYFPTGLYVdeelKVAIPHTEV---NFANKNVLVVVKPLNSVHFYRMDKPdveIeVDIIFALVIkDSHEYLKFLSKLTENLTNEEFVKLIKTG-NLENISAYIKN-- +>tr|S2S8D1|S2S8D1_LACPA PTS system mannitol/fructose-specific transporter subunit IIA domain-containing protein OS=Lactobacillus paracasei subsp. parac +-----RNLVLNRVDAVNQKELFDLAASKLLMEGYVKQTYLEGLTTRESKFPTGLKTksiDVAIPHCDP---EYIDKDGVLVVRPIKPIIFNEMVNPtnsVqSRLIFFICStGGTEQLESLRQMMNIFKDDKFLTTLYQAEDMMPLLFSWKG-- +>tr|G5HDM8|G5HDM8_9FIRM Uncharacterized protein OS=[Clostridium] citroniae WAL-17108 GN=HMPREF9469_00690 PE=4 SV=1 +-----ENIFVMDGSADSWEDAIQICTERLIEEGVVKPSFKEACLKREQAFPTGLPTapGVAIPHAGN---EHVYENGICLLRLKHPVLFQRLDVPeetVpVNFVYNLATsESEGHIDILKKLMESIHSGQILKDYMDVPLEQLYDMVYKQ-- +>tr|A0A1C6B6L1|A0A1C6B6L1_9FIRM Multiphosphoryl transfer protein 1 OS=uncultured Ruminococcus sp. GN=fryA PE=4 SV=1 +-----DNLVFHNLKASDNIEVLQLMGDAMIQEGYGEEGFTEAVLKREKDYPTGLDVngiGVAIPHTDA---EHVKKEGLSIAVLNPPIEFDAMGEEdcrIpVKIVIMFTVaGKDKHIDRLLQVLDMIKDEEILQGLLDAKNKKEIRTVIQK-- +>tr|A0A1J0H4N9|A0A1J0H4N9_VIRHA Uncharacterized protein OS=Virgibacillus halodenitrificans GN=BME96_15085 PE=4 SV=1 +-----KDIFMMNLTVGTKEQALTAMCSMLINTGYVTADFMEEILKREQGFPTGLPVqpyGVAVPHVDS---KHVIESQVVFAALKKPVVFQQMGNNqqnIdVSFIFMLAFrDPTEHLQHLQKLFLCLQDTAFMQQLNQIKNKSHLLQLINN-- +>tr|A0A1J7VRH9|A0A1J7VRH9_STRAG PTS galactose transporter subunit IIA OS=Streptococcus agalactiae serogroup III GN=A9249_07340 PE=4 SV=1 +-----TQDILFI-DAHSQEELFDLVSKALIKQHYVSPDYRQAVKEREREFPTGLKIdlkdgtpiqYVAIPHTET---QYCLVDRIFYVKNSQPITFKHMINPeeeCrVQDFFFIINsRNSNQSDILSNLITFFITKGNLDRLHELGDNKeKINHYLIE-- +>tr|A0A140DZ70|A0A140DZ70_MYCMY Mannitol-specific phosphotransferase enzyme IIA component OS=Mycoplasma mycoides subsp. mycoides GN=mtlF PE=4 SV=1 +---NIYKKIYLNKTFNSKQECLDYLKELLKQEN-VSLEYIDSINKREEDCSFNIGSKIAIPHGIYEGMLSLKNSLIVVIHLQKPLIWDNSE---VQLVIGLALKQEDQIDMLQNIAINAMNDDLFNDLLKNPTIDKVISFCT--- +>tr|A0A084U359|A0A084U359_MYCIO PTS system, mannitol-specific IIA component OS=Mycoplasma iowae DK-CPA GN=P271_228 PE=4 SV=1 +---LNTNNILIGVDIKNKNDAFNKVFECLKKQNAIEDKYLNSMIERDKNSSVAIGNFIAIAHGTVETKDLIKKDAMCILVLKNPIDWDGNE---VKVVLGLALSGDKTMDVIGNIGVAFSDEEEVKNFYYKNDltSNEVLKWLV--- +>sp|P75145|PTMA_MYCPN Mannitol-specific phosphotransferase enzyme IIA component OS=Mycoplasma pneumoniae (strain ATCC 29342 / M129) GN=mtlF PE=3 SV=1 +---LLKNNIYINVYLKNKQEIFEFVFKKFKEDGAVLDSFLPAIVERDKAASVAIGNYLFLPHPVYDEIANIQKEKMVFIGLKDVINIDGQP---IKFICGLALKGEHQMDALQSLAIAFSDPEEVEKLVKDKDltQDKVLEFLA--- +>tr|E5VQI2|E5VQI2_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase OS=Anaerostipes sp. 3_2_56FAA GN=HMPREF1011_00254 PE=4 SV=1 +-----EDLIWLDETFEDKDQFFDKIGKRLYEKGKVKESFADGLKSREAVYPTGLkteSYEIAIPHTDV---EHVREASISFVRFKETVLFSHMGEPeiqvNAKFAFVLGVKEpSQQVEVLSTLVLLISNEAEMAKLEVLNAPAQICALLNE-- +>tr|A0A0K8JBW2|A0A0K8JBW2_9FIRM Uncharacterized protein OS=Propionispora sp. Iso2/2 GN=P22_1074 PE=4 SV=1 +-----EKLVKVGVQVPSREALITAMGTMLVEQGFVKPSYIPALLAREKEFPTGIaaaaGVGVAIPHSDA---GHVLKTAASVWVLDKSIPFHVMGGGqedilEVNIVFMLAVHNpQEHLMFLQKLLGLFSKEDVMLKLRNAANATCIAETINL-- +>tr|A0A135PBN0|A0A135PBN0_9ACTN Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Atopobium vaginae GN=HMPREF3232_00779 PE=4 SV=1 +-----REMIFPKLEFDSRTEVLQYMAHQFTKLDLAKESYAAALIEREAHFPTGIsarAFDIAIPHCAS---ENVNRTSMAVATLTHSVGWHAMDDPnkilQPTVVFMLAIKDpDKQIETLQKIMEIIQNSQLLQDISVAVTRDEIFSKLDP-- +>tr|A0A094Q411|A0A094Q411_9ACTN Uncharacterized protein OS=actinobacterium acAMD-5 GN=GM45_2780 PE=4 SV=1 +-----DDFCSASLKADSALDALTQIATLGYENNLVAQSWLAAVTQREQDFPTGLpta-VPVAIPHTDS---IHVKQDGIGYFRLTQPVEFGEMGSLenkiKVSVIIPLLITNpKDQTSLLMSVIALVQDFEFMNQLILLDSKTQVANFLNE-- +>tr|G5IKK0|G5IKK0_9CLOT Uncharacterized protein OS=Hungatella hathewayi WAL-18680 GN=HMPREF9473_04028 PE=4 SV=1 +-----KKGFFQKKRYDSRQDYLSNTADMLEREGLVKEGFKKVLMDREDNYPTGIqtiTVPVSIPHAEF---SYVNQESIVVTVFEKPVLFRRMDAPeeevGAEISFMLLLRDaHSHLTVLQQLSGLLQSDKL-ARIRETDSMEKLAQILQE-- +>tr|R2QDF1|R2QDF1_9ENTE Uncharacterized protein OS=Enterococcus pallens ATCC BAA-351 GN=UAU_02157 PE=4 SV=1 +-----KDFLYCQYTVKNKEELFDRLTGDLMAKNIVREGFSQALKDREAEFPTGLpvk-HGVAIPHTDG---SLVNSDQLLFVTLTEPIIFNEMGGDdedtvEVNVVVMLAVKDgKKHLTVLQNLIEAIQKEGFVDQLVDATDEEQILAAVNA-- +>tr|S0JCP9|S0JCP9_9ENTE Uncharacterized protein OS=Enterococcus saccharolyticus subsp. saccharolyticus ATCC 43076 GN=OMQ_02130 PE=4 SV=1 +-----KKEIMYQTNFQTKEELFQGVTAFLVDKGFATAEFEAALREREERFPTGLpse-PPAAIPHSDG---TYAKEDVIVGILNEQPLEFYQMGTNkstllHPRIVFVLLVRDkVTHLDQLQRIIEKAKDHDFLVRLQDASDEGQFTSLIQE-- +>tr|A0A0D6JLB6|A0A0D6JLB6_9EURY PTS system galactitol-specific transporter subunit IIA OS=Haloferax massiliensis GN=BN996_00126 PE=4 SV=1 +-----MRTESLELTGETDEAVLTELGAYAYDRGWADESYADALLAREADYPTGLdiptmGFGIAIPHADP---DHVSEQAVLLglPPAGESVAFRSMDNPdervDAEVVVLLLVTDtEGYSSFLSNLAKLFQAEEFAELTKRRDADG-LLDLVVE-- +>tr|A0A1N6R1X4|A0A1N6R1X4_9SPIO PTS system IIA component, Gat family OS=Spirochaeta americana GN=SAMN05920897_105136 PE=4 SV=1 +-----PSLVLDDLAGDSREEILRTMAEYLVKEGRCRRTFVEAILARERLYPSGLpleGPKIAIPHTDT---IHVHRSALLFVRLRTPVEFASMGDPkvtfPVQLVSMFALQNdDLVGNVLQTLITLYQRRQMLEDLLRSKDAREMYQILVS-- +>tr|A0A1Y4L6S6|A0A1Y4L6S6_9CLOT Uncharacterized protein OS=Butyricicoccus pullicaecorum GN=B5F17_09040 PE=4 SV=1 +-----EKNIILDCDAQNWEQVIRIAGARLRENGYIDDAYIEAIIEREKEYPTGLptdDVITALPHANS---GAVYKTGVCAVRLAHPVDFRNMGDPeetlPVEMAFVLANAsGpDAHLEDLQELMDCFTRVGLLADLKRAQSVAAFQEVFAA-- +>tr|A0A1Y3U0P5|A0A1Y3U0P5_9ACTN PTS galactitol transporter subunit IIA OS=Enorma massiliensis GN=B5G21_07690 PE=4 SV=1 +-----SLVRIFNENALDTYSVEEELAGALCAGGWVKETYANALHEREEAFPTALdaqGINVAIPHCET---EHVNQGAVAVGVLKHPVSWRRMDDSsqtcDVSLVVMLALVEaHAHLEMLQKVIAIVQDQEFVGTVIAQDEPQEVYRLLSD-- +>tr|C3WAJ2|C3WAJ2_FUSMR Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Fusobacterium mortiferum ATCC 9817 GN=FMAG_00441 PE=4 +-----KQI--IVTDLTTKQDFFKTIADLAFENNILSDkeEVILGLNERESKGSTGLLDGFAIPHAQT---PSIKKAAVVIVKSTNKVGWESLDGEPINTAICLLVpksqAGTTHIDFLTEISKLLMDDDFRANLNKLNDSHSIYEAFL--- +>tr|A0A0M2ALT6|A0A0M2ALT6_ENTFC PTS system ascorbate-specific transporter subunit IIA OS=Enterococcus faecium EnGen0153 GN=SIE_00828 PE=4 SV=1 +------EMIQLSDQPKNWQEAITFAAQPLLSLVALMYVLQRYEFllyqldkSAIFHMDVfvH-------------------------------------------------------------------------------------------- +>tr|H9UFA3|H9UFA3_SPIAZ Phosphotransferase system mannitol/fructose-specifc IIA component (Ntr-type) OS=Spirochaeta africana (strain ATCC 700263 / DSM +---FDNGSVVWELESETKYDAIHEVIYRSPIFRNlpGfdLDQFYQVVHHRESLQSTGFGHGVAVAHGRTPM---VADSVVALGVSRQGIDYQAMDNRPVHLLFVVATHPDqqlNYLKVLSSLITLVRQESFRREIFACLCQEEIEEKLCH-- +>tr|F2LUE8|F2LUE8_HIPMA Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Hippea maritima (strain ATCC 700847 / DSM 10411 / MH2) GN=Hipma_0503 +---IN--TVKLNINCKEKFECLKKMAEYLAKEN-NlnSEDVFSLLMAREKFGSTAVGGYFALPHAKMDS---LSKLICGIFTTEEPIDFGSLDGVPSQIFLVVLAPSSkpsILLKALAKAAKIFKDNQLKERIISEKDKEKVIEFIKN-- +>tr|A0A0F9RK65|A0A0F9RK65_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0634850 PE=4 SV=1 +---LTQDMIILELESENAEGILREMVRFLRK--KdiVskEKELYEKLVQREKLGSTAIGEGIAIPHCKIKR---VKNPVVMLAISKKSVDFCSLDGKPSNIFFMVVSSPDnpsINLQILAAIAHLVRKSgSLAKKILKAKNISAVMDVIRE-- +>tr|A0A0S7XI28|A0A0S7XI28_9BACT Uncharacterized protein OS=Latescibacteria bacterium DG_63 GN=AMJ46_00825 PE=4 SV=1 +---LNEKAICTSLKSSAKEEVIEELVNLLEEAHGidSGGEILNRVVEREAMMSTGIGNGVAIPHGKARS---IHSLLAACGIAPEGLDFQSVDGESVILFILLVSPEEfrgPHVRALANISRLLKEEDTREHLKRSASAQEFLEVLKQ-- +>tr|B6G220|B6G220_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=[Clostridium] hiranonis DSM 13275 GN=CLOHIR_02182 PE=4 +----MKESIILNFDLnekyISKEELFKEITKLLHNNNCIelENKFLEELLYRESLGSTAIGNEFAIPHATYEKGANIPC--IIVCKLKYSIKWDDAGKFFVKNIILFANPKLevnkKGLKLMASICRTLANEEICIKMSNMKCSKEMANFIYD-- +>tr|G8QYK7|G8QYK7_SPHPG Phosphotransferase system mannitol/fructose-specifc IIA component (Ntr-type) OS=Sphaerochaeta pleomorpha (strain ATCC BAA-1885 +---LDKDLVKVPLNAIDKLGIIGELVDVVTKAKGysSqqHDDILNAVLSRESLGSTGIGNGIAIPHAKTDA---VDHVSMVVGISRIPVDFSSPDEVKSKIFFLVLAPSKeasAHVELLASIARTCTSQIFRRMLEQSKNRDEVVRLFME-- +>tr|A0A1F4X9W2|A0A1F4X9W2_9BACT Uncharacterized protein OS=candidate division Zixibacteria bacterium RBG_16_50_21 GN=A2Z27_04045 PE=4 SV=1 +---IHPDLIKVELETavpeeveeilkpeirveRIKELLVKEFVEILSLSGKIqsSNKLYLDLLNRERKASTAIGHGVAIPHVRTMH---AREFVMGLAKSTEGYEFGSPDGQRVHLFFLMVSPNYddnLYLKVYKGLADLLKYEELREKLLHASSVREVIGALQK-- +>tr|A0A1G3R8N1|A0A1G3R8N1_9SPIR Uncharacterized protein OS=Spirochaetes bacterium RBG_13_68_11 GN=A2177_13905 PE=4 SV=1 +---IARERIA-FIEAENKQDALAKLIALSEDDRLvIdFNQFQNAVLDREYIVTTGIGQNVAIPHIKSRW---VRDFFISIGVFRNGVEWQSLDEKPVHLAFLIAGPEEheRYLRILAKLTLIIRDKEKRKAIIGASSPDEVYRLLEN-- +>tr|A0A1G3QED9|A0A1G3QED9_9SPIR Uncharacterized protein OS=Spirochaetes bacterium RBG_13_51_14 GN=A2176_02325 PE=4 SV=1 +---LKRQNIFLKAKSTNRWDLINEMVDLAAKNREvePsdSDEIKKSLIDREKSMSTGIGNGVAIPHCTTAK---VQDIIIVISIIPRGLDFDSIDNQPVKIVILLLVPKNkltQHIKTLANIAKLMSNENLRNKLLAIKTPDGIIKTIKD-- +>tr|A0A1G1M315|A0A1G1M315_9BACT Uncharacterized protein OS=Omnitrophica bacterium RIFOXYB12_FULL_50_7 GN=A2351_03360 PE=4 SV=1 +---LHEENIVVGLDALNHEDALKKIVDVLPGWSLqGieKQKILELLILRERIGTTAIGHGIALPHCFSSE---VHEPIVAFGVSSSGVPFPSLDGRPVHFIFVLILPRNdaaERQKrqILQNIKWSLCDRYLQERLKGAQTASEIHRLIVS-- +>tr|A0A1M6M9C8|A0A1M6M9C8_9BACT Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Rubritalea squalenifaciens DSM 18772 GN=SAMN02745 +---LTVEQVMLDMKSEEHWPAIVELVEHLDKEGLlaPenKEDVLAALQVREDQISTGIGSGVAIPHAFSDK---LEHVVAMFGRSKDGIDFEALDNAPVNFVLLFVVPKKdyhMHLQTLAAIAKMFNNCEVRQQLAEAETRRDILEILGS-- +>tr|A0A1Q2HQI4|A0A1Q2HQI4_9BACT EIIABC-Fru OS=Phycisphaerae bacterium L21-RPul-D3 GN=fruA_2 PE=4 SV=1 +---VCPEAIVVKLKSTDRDGVITELVDSLVESGQldKdkRDQAVKAVIDRENEASTGIGKGVAVPHVKSSL---ADTPIGAFGLSSEGIDFLSLDKQLVYSVFLVIGPEAnpdQHLLAMEIIFKNLQKDDFRSFLRQSKSTEDVVTLLEE-- +>tr|A0A1V4QT45|A0A1V4QT45_9BACT Uncharacterized protein OS=Candidatus Latescibacteria bacterium 4484_107 GN=B1H02_06030 PE=4 SV=1 +---LDASNVVLNIEGKRRTQIIEKIIQQLHHAGAAfdEEEALEKVLKREELGGTGIGFGVALPHARLNS---AEDILVGLGISKKGIDFEAMDGQPARLIFLVLAPEKeaeTYLKVMARISRLMRKEEVREELLCCDIESDVASIIEK-- +>tr|A0A1T4JW83|A0A1T4JW83_9FUSO PTS system, nitrogen regulatory IIA component OS=Cetobacterium ceti GN=SAMN02745174_00123 PE=4 SV=1 +---FNSKLITLIDNKnSSKDDILKDMVHLIKENTNyLedEEDFYNQIIEREKVGSTGIGMGIAIPHARSQA---LDKIVVAIGLLKTPVNFNSLDGEYVKVVVLVGAPKEqskEYLGLLSTLARIFRNKKSRESIMDSSTLEELIEAIAE-- +>tr|A0A1W9S016|A0A1W9S016_9BACT Uncharacterized protein OS=candidate division Zixibacteria bacterium 4484_93 GN=B6D65_00270 PE=4 SV=1 +---LKEETVNLNITQgklpdkptedytnadrwRMKENVIRQIVELVEHSGLVgnKKKLLLDFVNREKRCTTAIGSGIAIPHIRTMQ---VRGFVFAIGISKDGVYFASMDGAPTHIFFILASPPYddtDYLQIYRRISELVQNQNIFFELTTAGTPGELIRIVKD-- +>tr|A0A1W9RCL1|A0A1W9RCL1_9BACT Uncharacterized protein OS=Candidatus Omnitrophica bacterium 4484_70.1 GN=B6D56_00335 PE=4 SV=1 +---LDKRDILFKIKGKGKKSVITFFVDHLISTKKvdKkyRKEIIKSLLQREEMGSTAIGGGVALPHARLES---VKKVVLCLGISPQGINFDSLDGEPVYIIALLLSHHKeagLHLKILALLARILKDKYFVQRLKEVSQQEEVISLLRR-- +>tr|A0A1V6BYM8|A0A1V6BYM8_9SPIR PTS system fructose-specific EIIABC component OS=Spirochaetes bacterium ADurb.Bin133 GN=fruA_1 PE=4 SV=1 +---LKVEHCKIGINAKSKDDILHELAEFLSASHkGIidKEDAYKSLKERENKGSTGIGKGLAVPHGQSDK---LNGIALIIAYDKNGKDFNSYDNRPTHLFFVGITSSEynpnDHLKLLKIIAAIFEKSNIAQQLETVKEPADIYNLIIK-- +>tr|A0A1V6EUJ0|A0A1V6EUJ0_9BACT PTS system fructose-specific EIIABC component OS=Candidatus Cloacimonetes bacterium ADurb.Bin089 GN=fruA PE=4 SV=1 +---FMPELIKIVEQFENKNACLQYMANLLSESGCLsfPDRFLAAVKGREEIMSTGIGRGIAIPHARDLT---VSCLRIAVCLVKQDLEFTSLDNSPVHLVFMIAVPQSsnqDYMKILRSLSEFLRQDENREILLQAKDERDLYEKVQI-- +>tr|A0A1F6CQ84|A0A1F6CQ84_HANXR Uncharacterized protein OS=Handelsmanbacteria sp. (strain RIFCSPLOWO2_12_FULL_64_10) GN=A3F84_22585 PE=4 SV=1 +--------MILHLQAQKRMEAIRELASRLEGSDEIvdVKRFLSLVMQREKIETTAVGHGVAIPHAHGDC---VKSLVIGVGVSRQGIDFGAMDGEQVGIVVMIASPVRhfqDYLKAVSRVARLLNQEDCRQRILNAQGVAEVIEVFKQ-- +>tr|A0A1Z9N4K8|A0A1Z9N4K8_9FLAO Uncharacterized protein OS=Flavobacteriaceae bacterium TMED208 GN=CBD68_05510 PE=4 SV=1 +---LIPAFIELNIEVQNKFQLISSLVDKFDQKG-iLseKKEYLDAVLERENLLSTYCGYNVAIPHAVSKS---VKNSAFGFCRT-KPMEWDKNDEHVQ-FILILAIPdssNSnesKHIDMMSQIASLALEEEIRKIWKSAKSKDVITKTFN--- +>tr|K6PGJ9|K6PGJ9_LACCA PTS system, fructose-specific IIABC component OS=Lactobacillus casei 21/1 GN=LCA211_2417 PE=4 SV=1 +-----NDLIILDQDYSSKREVFQAVADRLKQKGTISntSNFIDSLYAREKDGPTGMDKGVAIPHAKSS---QIKEPVFSIVRTKKPIdDWESIQPdNKVSLIFLLAIPksdaGDFQVKLLAKLSRAMLDDQFISTVMKASSTGQVMAELGR-- +>tr|D0IAK8|D0IAK8_GRIHO Phosphotransferase system fructose-specific IIB and IIC subunit OS=Grimontia hollisae CIP 101886 GN=VHA_002785 PE=4 SV=1 +------------------------MKAIIVT------------SCPSGIANTIIAAGLLEKASAALQWTVTVECQ---TTVKATEKLTQSAIEAAELIIAVgPVSdmarFTGKKVYQAELSACYSDAKQLLEHAA-----MNASVYTH-- +>tr|A0A1B7L9G8|A0A1B7L9G8_9ENTR PTS fructose transporter subunit IIBC OS=Mangrovibacter sp. MP23 GN=A9B99_04655 PE=4 SV=1 +------------------------MKTLLII------------DPGLGQARCYLAKTLVAAAA-----------------KKANLEIIDNP-NEAEMAVVVgtEIKpdtaLNGKKVFLGNIDRAVQHPELFLNEAK-----EKAVVYTA-- +>tr|A0A1L4DE60|A0A1L4DE60_BORAF PTS fructose transporter subunit IIA OS=Borreliella afzelii GN=BLA32_01095 PE=4 SV=1 +----SKNLIALNYNATSKEDVIRKMASMLNENGYLNdmEAFIKEIKKREEINGTGIEEHIAMPHAKGDF---IKKHGIAILRInGNGFDFNSSDQKLSKLFFMMALPeeiPsNAHIKAISYLSNTFSNNLLRHELMNTNNEDRFLEIIMN-- +>tr|A0A1B9LID7|A0A1B9LID7_9GAMM Uncharacterized protein OS=Gilliamella apicola GN=A9G11_12910 PE=4 SV=1 +------SLITLDVDCQTAEQAIERAGELLVKAQLCTDDYVSAMKQVYQNFGAYivLDNAIAMPHARPEH--GAKATGFSIITLKNPIEFGNEDFDPVTVVVAIVSNElDAHVDLIQLIATLIEND-LVSVAQRSTTPQSLVNFVE--- +>tr|E7G924|E7G924_9FIRM PTS system protein OS=Coprobacillus sp. 29_1 GN=HMPREF9488_01262 PE=4 SV=1 +----------TEKNVSSDLEAIEVAGSVLVQEGRVMPEFITACTDREKIYPTGLglpsGQAVAMPHGES---SFVKEDSISIVRTQTPVVFKRMEDPDQtvkcQLIFNLAlATGGKHITVLRKLMGLFQDEMFIQNCM-QYDNISLIK------ +>tr|A0A1Y3XXS2|A0A1Y3XXS2_9ACTN Uncharacterized protein OS=[Collinsella] massiliensis GN=B5G02_00875 PE=4 SV=1 +----------DADAPATWEEALRTLGAAFVEHGCATPEYIEAAVTRERAFPTGLdlgAWAVALPHGDP---IGVLHGAISVGRFERPVRFRRMDDAERevevEAVFFMAvDDPERHLAVLSKLMEVIGSGSCRREMLVAYDGEAIAN------ +>tr|A0A0R1KE09|A0A0R1KE09_9LACO Phosphotransferase system mannitol fructose-specific IIA domain containing protein OS=Lactobacillus paralimentarius DSM 19674 G +----KENLIKLHVKSHDWKEAIKLSAQPLVDDEIVTSNYVNEIINSVNeYGPYfVIAPHVALAHAPGKA--GAKELAMGISVLEPAIEFNNADNDPVSYVFTLSAPdSNSHLKAMQELVYLLTDDNFYQVLSNSQKPSEILQYIKDSV +>tr|R6UZB6|R6UZB6_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium CAG:64 GN=BN746_03528 PE=4 SV=1 +----KEENVEVGVHAADWEDAIRRSAQHLLETGKIEERYIRAMIDAVHrVGPYiVLGNHVALAHARPEC--GVNELSVHFTTLQPPIPFGSEKFDPVSLIITLAAVdADSHLELISELADILMEETHVERLSSCTTEREFVELLRRMK +>tr|K1XNA3|K1XNA3_9ZZZZ Uncharacterized protein OS=groundwater metagenome GN=ACD_79C01047G0003 PE=4 SV=1 +---LINDGIVLEPKISNKWLILEQLTGFFCRQLPLSiaDQILETVLNREMIVSTGLGGGIAIPHARTDLVQ---KTELLFARFKSGVEWNSIDGSSVNFLFLVIGPtssAEEYLFVLSKISKLLSRKQNKDELLHAKSSKEIYMILSS-- +>tr|A0A0J7HTL9|A0A0J7HTL9_9BACT Phosphotransferase system mannitol/fructose-specifc IIA component OS=Chitinispirillum alkaliphilum GN=CHISP_1303 PE=4 SV=1 +---LPKNAILTDIKKTDKNEVLRDMTHFMASLYNLnhd-pEILTQKILEREAEISTGIGYGIAIPHVRLAGID---RCYMAAARSKTGIDFNAIDDQPVHMLFMLFSPvntSTEHTQILSSLSRIMTWEEIREKLLQVDEAQEFLDVLTE-- +>tr|I0XAB0|I0XAB0_9SPIO Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Treponema sp. JC4 GN=MSI_08290 PE=4 SV=1 +---ITPSDINLNLESTDKEEAFAELTEMLVKKCPGln-rTEYMKAVTERENKCSTAVFPKVAVPHAVCDSAS---KTTIVVGISHDGIEFEPLESAdntnpVVNIIFQIVFErenTGSHLNVLRDILYIVSKPEFYEKILTLKTQKEIFDLFTE-- +>tr|D3PD43|D3PD43_DEFDS PTS system, fructose-specific enzyme II, A component OS=Deferribacter desulfuricans (strain DSM 14783 / JCM 11476 / NBRC 101012 +---VDEKHVIFIDEKLDKDALLKLFAEKFRELDAISdsQAIFEALYERELLSSTAVGEEVAIPHAKLANLD---DIKMIIAISKVGQDFQAVDNLPVKLFFVVIAPankMQLHLKALARISRLVKMTDFKKRALEQDSAKKVIDILVE-- +>tr|G7Q482|G7Q482_9DELT Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Desulfovibrio sp. FW1012B GN=DFW101_0936 PE=4 SV=1 +---LQPEFVIGELAAESKSEVLAELVAKIAAGLPGFdaKRAHQVLLDRESLGTTGIGDTVAIPHGKMESLE---KIVIAVGRSLKGVNFDALDFKPCRIFFLVLAPehvAGLHLRILAHISRLLSDESFRHAFLSAENDAALWQVLTA-- +>tr|A0A192X050|A0A192X050_9BACT Uncharacterized protein OS=Acidobacteria bacterium Mor1 GN=ABI59_16845 PE=4 SV=1 +-------MVRVGLEAVDRLGLFRALVGDLAAREEFQnqQAVFDAVVHREGQRSTAVGEGFALPHATSEHVP---GLLMAAARLARPIEFEAPDKEPVDLVFLVLAPpaeMAPFLVLLGRLARVVSRKDVASDLRSAPDEESFEAKLQE-- +>tr|X0TWP6|X0TWP6_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S01H1_29742 PE=4 SV=1 +---LKENNIFFDLEPGEKRHVLEEFVSALKKRGLIs-neKVILEELLKRESLGSTGLEKGIAIPHALIENID---DPIVALALIKSGVNFDAVDQMPTYIILLLLGGkdnPGFQLRLIAHICRMVKETDFVEKAKKAESSHD--------- +>tr|A0A1G3R026|A0A1G3R026_9SPIR Uncharacterized protein OS=Spirochaetes bacterium RBG_13_68_11 GN=A2177_03875 PE=4 SV=1 +---VHPECFIHDLAAKTREEALREIVSVAAAKGIIKdqAAVLERLLERERIQSTAVGSGIAIPHCFTDEVA---DLVIVVARAPGGIAFDSFDGRPTHVVFLLMGNrqeHGLHLKALARIARLIKSTAFIDRVVAADSVEGMVRAFEE-- +>tr|A0A1F5FHA6|A0A1F5FHA6_9BACT Uncharacterized protein OS=Candidatus Coatesbacteria bacterium RBG_13_66_14 GN=A2Y64_04185 PE=4 SV=1 +---IEKKAVLLELKAGTKDELLKALIGAVGRSSRVKdpAAAREAILEREELSSTGMGYGVAMPHARVKSVT---FPVLGFARLAGGVDYGSVDSEPVRLVFLLLTPatnPELNVQLLGKISRICQREDNRRRLLGVEKTGDFLTFIRE-- +>tr|A0A1G1KR18|A0A1G1KR18_9BACT Uncharacterized protein OS=Omnitrophica bacterium RIFCSPLOWO2_01_FULL_45_24 GN=A3K16_04305 PE=4 SV=1 +---FKKDFCSLDLKAATKEGAIREIAALLSKSGKLkd-nERFVSDLLGKWRHNPGCFDKKTAIAHSLSESVD---GLVAGFGRSKNGIDFNAPDCEKANLVFLIGANprdLDIYLVMLAKLSKLLSEEFFRRELSSAVTHSEIISIIKR-- +>tr|A0A1J4V7K3|A0A1J4V7K3_9BACT Uncharacterized protein OS=Candidatus Hydrogenedentes bacterium CG1_02_42_14 GN=AUJ18_04070 PE=4 SV=1 +---LVAKAISLD-LPSDKNEAIKVAIKALTKNLSLe-eDEVFEAVMAREKALSTAIGLGVAIPHAKIKSIK---KFAYSIFCSEDPINFQAPDKTPVRIIVLLLSPenkMKEHVTLLAEISRRLKFSHVRQAILEAKTPKKVAEAFLQ-- +>tr|A0A1G3KSL9|A0A1G3KSL9_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWB1_27_13 GN=A2Z98_13265 PE=4 SV=1 +---LSPERIMV-LEESNQKEMVEKLLTMIKGSPLIkn-fDTIKDAIWEREKIISTGIGLELAIPHTRREDIK---GFIASAVLVKKGVDWKAIDDKLVKFAILVCSPsdsHKQYLKLLAQTVLLWKDDYKRKKILESNDPFQIYNILKE-- +>tr|A0A0S8FG87|A0A0S8FG87_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium SG8_31 GN=AMJ59_09660 PE=4 SV=1 +---IEPSRVLRNVDARSKKHALDILSEMIAGAdDeLAQGAVFDSLISREKVGCTALPGGVAIPHGCIDGLE---RIIGAFVKLAHPVDYDTPDGVPVDLMFAIVLpdiAGTERKACLKEAGQIFGDPAFQRMLRSAKSSRTLYDMII--- +>tr|M1L379|M1L379_9PROT PTS system, nitrogen regulatory IIA component OS=Candidatus Kinetoplastibacterium desouzaii TCC079E GN=CDSE_0090 PE=4 SV=1 +---LPIDNILLEMSATSKKRAFENISLFFERKhDISSSAVFKSLLAREKIGSTYIGNNLAIPHGYVYDLK---KTIAAFVRLNRPIIFYNQNRQLVNTLMFFLVplnQAEEHIKILTKLTSNLLDKTTNKILQTED-KKIIYNTII--- +>tr|A0A1G0YQY1|A0A1G0YQY1_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_52_8 GN=A2X49_13160 PE=4 SV=1 +---LRQENLICGLRAASRDDALSQLCTLLAEKaGtpEEAKQWLTALLAREKIMPTVLSPGFAMPHARIANLK---NAMIAAASIPAGLDFNTKTPQPVKLLVLLLTpanDPQLHLKVIKDIAAAFIQRSAEEidAIAAIESP---SDLLA--- +>tr|A0A1V5QGE9|A0A1V5QGE9_9BACT PTS system fructose-specific EIIABC component OS=Verrucomicrobia bacterium ADurb.Bin345 GN=fruA_2 PE=4 SV=1 +---LKANTIRTDIGQLDKWTAIERLADLIVDSgKaTDRAALLDAILNREKQGSTGLGNGIAIPHARTDGVR---DVAVALGVSASGMDFDSADGKPCHLIFLIAAplhESTRYLEALAAVASLGERASLVAQLKSVRSVDDALAFFK--- +>tr|A0A1X4XV39|A0A1X4XV39_9DELT PTS IIA-like nitrogen-regulatory protein PtsN OS=Desulfurella amilsii GN=DESAMIL20_948 PE=4 SV=1 +---NQIKDVDVNVVANDKYDLFQKISQSVALKvNVDSSIIYDLLKERELLGSTAIGNGFALPHLKLKDVK---SYIGVFV-LKAPIDFDSIDDITVSVIFVVLSpsdKPSLQLKTLTFLAKILKKSNVEHFLNK--SPQEIKDYLK--- +>tr|A0A229FVV2|A0A229FVV2_9BURK PTS sugar transporter subunit IIA OS=Polynucleobacter cosmopolitanus GN=AOC33_01325 PE=4 SV=1 +---ITPNNISLDIEVSSREELFIFIAQQFEKN-hgISANSVIACLEEREALGSTALGNGIAIPHGRVKFLE---QAHIGFVRLKESINFHATDKQPVKALVIMLVpeaATQAHLDILAKIAQTISNNKNKNILLTEPSADNIYQLLT--- +>tr|A0A1I0GHA5|A0A1I0GHA5_9FIRM PTS system, fructose-specific IIA component/PTS system, fructose-specific IIC component OS=[Clostridium] sphenoides JCM 1415 GN +---IKKEYIFTGMEFGSKDEALRSIAEQAVSLGLCRDveGTYQGFLERESQGPTGMEDGFAIPHTRC---ESVIQTGIIVMKSKNELEWESFDEKPVHIMIALIVpkenYGNEHIQILASLSRMLMKQEFRNRIMESDSAGEIYEIIH--- +>tr|A0A1V9CEJ0|A0A1V9CEJ0_9BACI PTS glucose transporter subunit IIA OS=Bacillus stratosphericus GN=B2I20_12940 PE=4 SV=1 +---FQKDHVFTQVNGRSKNEILQYISEKAEDLHITDDqsGLLTDLLKREDEVSTGLQQGFAIPHTKS---SAVQTASLLFLELEQPIDWGSFDDLPTSYLFTLLVpleeANVTHLKLLSGIATSLMEPAFIEKIQPGQTADYYYEVIE--- +>tr|A0A0H0YSM4|A0A0H0YSM4_LACCA PTS system, galactitol-specific enzyme II, A component OS=Lactobacillus casei GN=AAW28_08970 PE=4 SV=1 +---FEEAFIYPKLDAASYEDAVRKMSQNLLEKGYVTSEYPDQVLAREKNFPTGLVlanMNIGIPHTEA---EYVKKTAVAVATLKSPVKVHSMIDpeqELpVSMMFMIAVSdPKGQVTILRELMRLFQDQDLMEKIMSEDTASGIYKLLKA-- +>tr|A0A0R1F830|A0A0R1F830_LACCA Phosphotransferase system galacitol-specific IIA domain-containing protein OS=Lactobacillus casei DSM 20011 = JCM 1134 GN=FC13_ +---FSDRVITFDQTFSDRNTALKAVADQLLKAGAVVPTFEKAIIAREQTYPTGLQlndgIGVAIPHTDA---DQVIHDQIGFVSLKTPVEFRQMASatdVVsVNYLFVLALKtAHQQLDMLQKLMELFADDAEMTAFRKIKTADDFIHFMTE-- +>tr|S0S710|S0S710_ENTAV Uncharacterized protein OS=Enterococcus avium ATCC 14025 GN=OMU_01386 PE=4 SV=1 +---ENQKFLYYSFDEDDKETLLAKMSEVLIDAEFVHPSYQQAVIERERIFPTGLPtkgINVAIPHTDS---IHVKKEGFLVGVLEKPVTFEMMASkdvFLeVELIFMLAIKqPEDQLVMLQKLMLLCQDEQNLQLLKAKEKVVEVEQLLKT-- +>tr|A0A0Q6DM22|A0A0Q6DM22_9RHIZ Uncharacterized protein OS=Aureimonas sp. Leaf460 GN=ASG54_22145 PE=4 SV=1 +---LDRRAVLVGMPAADHGEAIDHLAARLQEIGRVHPSWGPAARTREETMPTGLPlgdLNAAIPHTDP---EHVVEAAVGLAILPEPVRFQSMDDpdtGLdVRIVFALAIKdKAEQIPLLQAVIEALSDEKRLARLAAARNPDEAFTALES-- +>tr|A0A180CNN6|A0A180CNN6_LACRH PTS glucose transporter subunit IIABC OS=Lactobacillus rhamnosus GN=PY66_05885 PE=4 SV=1 +---FNEEIMTLHSDAPDAATIITKLAHQLEAKDLVTEKFLPHVLAREEKYPTGLAagpIGVAIPHTDS---IYVKESQIAFASLAKPISFKNMVDleqDVpVLLVFMITMSsPHEQTALLSNLMNMFQDQQTLQQLNQSDTKKQVIDILNT-- +>tr|A0A1E5U458|A0A1E5U458_9STAP PTS sugar transporter subunit IIA OS=Staphylococcus succinus GN=AST12_10205 PE=4 SV=1 +---IDASNVILNLEARTSDAALSELAELMYSNGYVKSSYKDAVIAREKSFATGLPtvyCSVAIPHTDI---EHVEAKSIGVAVLKDTVPFVIMGEakeTTdVKLIFMLAMDkEDAQLSLLQKLMGIFQNDQLLKTIVNAKARNEIAQVIEQ-- +>tr|A0A1E5KZ28|A0A1E5KZ28_9ENTE Uncharacterized protein OS=Enterococcus rivorum GN=BCR26_02275 PE=4 SV=1 +---LNEELVDILTIEGDQEEYFEKVYEKLNQLDYIEDGYLDAIIEREKEYPTGLQtpfLAVAIPHTDP---EFIKKPFIYLVKLKSPITFGQMGTtdtKIqVDCTFVLGMEkGEEQLVILQSLMKMFSNEEVMNKLRTVNNERDFYQTVRF-- +>tr|A0A1M6JHC1|A0A1M6JHC1_9FIRM PTS system, galactitol-specific IIA component OS=Propionispora hippei DSM 15287 GN=SAMN02745170_02605 PE=4 SV=1 +----TAESIYYDaviLeDMNSKEEIISCLANYLQQKGYVNEQYQAATLERELEYPTGLPtkpIGVAVPHSKT---ENVIRPAIVMAISRKLVEFGEMGNagaSLqVGIVFMLALQgENRHLNFLKHIINFCKQESNVTRLYQVPAREEAYRIFQE-- +>tr|A0A1S2B5G7|A0A1S2B5G7_PLUGE PTS glucose transporter subunit IIA OS=Pluralibacter gergoviae GN=BB778_05630 PE=4 SV=1 +---FSPQRIVVFNDAISRTALLNELAQKLLDDGFVKPDFAAGVLEREDKYPTGIDmetHSVAIPHTEF---CYVNSTGFAIGINHAGVAFQRSDDpekSVePQIIVMMAIDqSCEKVIIIQSLFALLADPKKVEEICQK-PPEEIAKIFTE-- +>tr|A0A127F0X9|A0A127F0X9_9RHIZ PTS IIA-like nitrogen-regulatory protein PtsN OS=Rhodoplanes sp. Z2-YC6860 GN=RHPLAN_57030 PE=4 SV=1 +---LSIERVIPNLYAADKSDALRKLAAVAAtNSAtPA-DLVVSAVLDGAEMPAFGPGTGISLPHAFIPGLGD---PFVIFAKLNPPVDFGSTDGSKTDLVALLlspLDn-PRGHLQALACVARTLRDVHVRKLLRGAESRDSIYAVLCG-- +>tr|A0A0S8JPF6|A0A0S8JPF6_9BACT Uncharacterized protein OS=candidate division BRC1 bacterium SM23_51 GN=AMJ85_04620 PE=4 SV=1 +---MREDLICTDLVETSKETVLQALVDHLVdRGEvENGDEVVRLLMEREQLMTTGVRTDFAIPHAFSEHVHR---SVVALGYVRAGVDWQSLDQQPVRYVFLLlgpPQs-KGSHLRLLARLSRLLSSPAFVHHLAQAKSPGEMLEAVTA-- +>tr|E6W110|E6W110_DESIS Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Desulfurispirillum indicum (strain ATCC BAA-1389 / S5) +---LQQEHICTAVDATTRDELLRVAAQKINsVCAdLSAQTLFQALWEREELGSTALGSQVAIPHCKIEGLDQ---IRLFVFTSARGIDFGSPDGQPTSLFFVIlspPQr-VSEHLQVLARIARLTRSDGFVSDALAASDPVRILQCIEQ-- +>tr|A0A011RQV2|A0A011RQV2_9LACT PTS IIA-like nitrogen-regulatory protein PtsN OS=Alkalibacterium sp. AK22 GN=ADIAL_0241 PE=4 SV=1 +---SIYASVAVEVK-GSKKDVLQTVIeEVRDkSGSvFDASEVLKEVLEREALSTTGFGNGFAIPHGKSSDLSD---PLVAVVKLADPVEWEAMDDEQVDILIMLivpKEgg-AQSHLKLLSQLSYNLMDEEIQNYLRKAESNEDLVSVVSG-- +>tr|C5BSX5|C5BSX5_TERTT Nitrogen regulatory protein OS=Teredinibacter turnerae (strain ATCC 39867 / T7901) GN=TERTU_3823 PE=4 SV=1 +---LNAKRTRAKIAGGSKKRLIETLAGIFSeSDtGLDQTELFQHIFARERLGSTGIGGGIAIPHCRFNTEGA---TLCACVTLEEAIDFDAVDSKPVDLIFAMlvpENAEDEHLQTLAALAETLQRDDFVKRLRNCKTDEELFNVASG-- +>tr|A0A1E3GQS6|A0A1E3GQS6_9GAMM Nitrogen regulatory protein OS=Methylophaga muralis GN=ptsN PE=4 SV=1 +---VNADNISFHDEATSKKRVIENLSRMLAanTSAATAEKIFQVLLERERLGSTGLGKGVAIPHARVPDLTH---TVAAMLTLETPIDFESADSKPIDIAFGLlvpEDDTEHHLQHLSRLVTLFRDEDICSRIRQASSADAIFELLLS-- +>tr|A0A1F9MLI2|A0A1F9MLI2_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFOXYD12_FULL_50_9 GN=A2511_17180 PE=4 SV=1 +---SGVLRVLPSLKAASKKDVLAELLEPVLaELGsIQASEVYQAIINRERLGATGIGQGAALPHALIAGFAN---HLAVCGRSGAGVSFDAADGKPIHFFLLYlapIGa-GTTYLHCLAMLAGFLRSAHVQARLLAVRDAKAIQAILDE-- +>tr|A0A1B3BCH0|A0A1B3BCH0_9GAMM Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Kangiella sediminilitoris GN=KS2013_1797 PE=4 SV=1 +---LAPERCQLGLQASSRKKALQVLANIFSqSCEsLDSFEILQALTEREQVGTTAIGNGIALPHGRLSNCEK---PIAILATLDTPVDFFASDKENIDVMFALlipKDl-DFRDLAGIEQVKTIFDNKTFCAQIRNAHNNEALFDIIEQ-- +>tr|A0A1F2QBT7|A0A1F2QBT7_9BACT Uncharacterized protein OS=Acidobacteria bacterium RBG_13_68_16 GN=A2Y78_12225 PE=4 SV=1 +---LKPEHVFLDIPAHTREEVLVYVAQRLEqAGAvQRSQDLVDLLLDRERLGATVVGDQTAIPHCKVPGLAR---VVAAFARALEPVAFDLDA-GFARLFFFIfspAEq-PSAHLQVLSSIARVLGDPNVRSAFEGASDANALTAALSR-- +>tr|A0A1T0AWK2|A0A1T0AWK2_9PAST PTS IIA-like nitrogen-regulatory protein PtsN OS=[Haemophilus] felis GN=B0188_09425 PE=4 SV=1 +---LTPGQIRHGVICSSKKRLFEIIAEIVSdYLHegDHTQCCFECLLTREKLGNSSLGNGIAMPKAKIPLGEK---PIAVFLQLTEAVEYESSDNREIDLVFALlipEKv-CADYVPHLAEMIEQLQDKNLCKQLRQAQSVEEIWRLFEH-- +>tr|A0A1V5PEH6|A0A1V5PEH6_9BACT PTS system fructose-specific EIIABC component OS=bacterium ADurb.Bin363 GN=fruA PE=4 SV=1 +---IKSENIFLDVKGKTKYDIIRNMINSSTiEEGlK--EYAYEKVKEREELQPTSVGNGIGIAHAKIEKIKE---LDILVGVLKKGVDYDAYDDKPVNIIFVIlspVEn-NREYLSVLSKISRFCRKENMIENIIQENNREYIIDLFSQ-- +>tr|A0A1W9M7E8|A0A1W9M7E8_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium IS3 GN=BWK80_41140 PE=4 SV=1 +---LRPENIFLNAELPDKDAVLRFVADACVrNRIvSEGDALYNGLRQREQSMSTGIGDGIAFPHSTHPEAAD---AAVLLIRPSKPLEFESIDSLPVGIILAIvipEHq-TALHLQILGGIARLCKNREILRTIREARDSESLWEFIRN-- +>tr|A0A1V5VBF3|A0A1V5VBF3_9BACT PTS system fructose-specific EIIABC component OS=Lentisphaerae bacterium ADurb.Bin242 GN=fruA_1 PE=4 SV=1 +---LSPERILILKGRLSKKEVLLAMIGTLAg--EyCDRDDLEWGIFHRESLMSTGIGSGIAIPHISLPNVEE---TRVAMALCPDgIADYQSQDSQPVRLVFMIvagKNq-KPPLLKVLAAIGTLFYDGRLKAAFLAAHDPKTCMEILIR-- +>tr|A0A235HB43|A0A235HB43_AZOBR Transcriptional regulator OS=Azospirillum brasilense GN=CHT98_18920 PE=4 SV=1 +---LSAHNVILDAGPANKETLLDLLATEAAsRIGTPKEDILKALQAREHIGSTALGKGVALPHTELRGTES---PLVLFARLRRPIDFEARDDEPVDLFFLVlwpTATRKGLLPVMGEICQALRDPQSLRKLRQAETPDAVVQLVRQ-- +>tr|A0A1Z9BLX6|A0A1Z9BLX6_9BACT Uncharacterized protein OS=Rhodothermaceae bacterium TMED105 GN=CBC65_03485 PE=4 SV=1 +---LSPDFIVMHPKVSSKKELFEQLLEALKpQCtSeAQFDAASEAVWARENVMSTAVGFGFALPHGKTHEVSQ---HMGVFGVLAEPLDYDGDNKEQVQLVFLLvgpKQe-SANHIKLLSQVSKLMNKEVLRQEILRASTAQEVYGLLKE-- +>tr|A0A1H4MN36|A0A1H4MN36_9ACTN PTS system IIA component, L-Asc family OS=Atopobium minutum GN=SAMN04489746_1149 PE=4 SV=1 +-----------KEEADDWKEAVRHACAPLVAHGSVPCEYSDEVVKSVEeLGPYiFLAPHIAMPHVQL---DGKTDLDVAVLKLNHPVVYDDN--HEAQLFVAFSARDGqSHIEMIQELATFLIKEKNVDALLKAKCESDIYQYIKTN- +>tr|R7G8I1|R7G8I1_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Eubacterium dolichum CAG:375 GN=BN631_00350 PE=4 SV=1 +-YKFIPELVETNISAKNKEEVIRFLAKKLADRKCVSSHYSELVLQREKEYPTGLitkGAVIAIPHAFDP---ETKGNNIAIGILKTPVGFKHMEDideTVpVKIVFMLAINgSHEHMEMLKILMQLVRDEELFKKLQSISSKNEICKLLN--- +>tr|A0A0K8JD04|A0A0K8JD04_9FIRM Uncharacterized protein OS=Propionispora sp. Iso2/2 GN=P22_1470 PE=4 SV=1 +-SLLTLESIHIGMPQQDRYEVLKVLSDSLKEQGFVTDGHYDALLKREMHFPTGIpagQFGIAIPHTDPA---YVRQAAIAVGILAHPVVFYQMGAettEVeVQMVFLLALTqANKQINMLQNITRLIRDGEALAFIRHSTSREEIRNKLQ--- +>tr|A0A1S8NS17|A0A1S8NS17_CLOBE Mannitol-specific phosphotransferase enzyme IIA component OS=Clostridium beijerinckii GN=mtlF_2 PE=4 SV=1 +-DLVKDELIDIAQEDLEYKEVISYLGNLLLKNNYIKEDYIKDVLLREEIFPTGLelkNMGIAIPHANPD---NVLKNGIAILKLKNPVRFSNMETgdDVyVNIVFMLALKnPDDHLKMLQSLFLMFQKEEVMDELGKVQSEEYIKIIML--- +>tr|N9WNX1|N9WNX1_CLOIN PTS system, fructose subfamily, IIA component OS=[Clostridium] innocuum 2959 GN=HMPREF1094_01657 PE=4 SV=1 +----TEQHIILDMEGNTQKEILHALAEIAFREGKVSdaDTFFQELCKREQECTTGFGKGIAIPHARH---ACIKEAGILFVRMKHKIEWKSIDEKPVEAAVCLLAPddkHDFHLKALSKLARRLMHEDFVDILKTAEKQ-QILSEIID-- +>tr|A0A1G4FMQ5|A0A1G4FMQ5_9FIRM Multiphosphoryl transfer protein 1 OS=Sporanaerobacter sp. PP17-6a GN=fryA_2 PE=4 SV=1 +----KKDYIFLDIGLKDKENSIDFIAGKAVELSISNdkDQTKKDLWSRERAFNTAIDETIAIPHTKS---ESINLPAIFIIKSKNIIDWG---GKNIKLIISFLTPkenkDNIHLTMLSKISRKLVDDKFKTTLNESDDINLIYELIMS-- +>tr|U2Q4U1|U2Q4U1_9CLOT MtlR family PTS modulated transcriptional regulator OS=Clostridium intestinale URNW GN=CINTURNW_2638 PE=4 SV=1 +------EFIELNAEYNTKEELIRSIRKKLKEANYVSDGFEESILMREERFTTEVGSGVAVPHGAF---DYVNTPIMIYIKLKEAIKWKE-E--LVDKVLLFCAREKDtakFIKFFRNFYNVIETEDEKRKLESFRDKRELKSYLED-- +>tr|A0A109MS40|A0A109MS40_9BACI Uncharacterized protein OS=Bacillus simplex GN=AS888_03210 PE=4 SV=1 +------DLIFLQMELSSPEEVIESICQTIITKQLASPDITKLVIEREMASPTSYGNLIAIPHPLK---HISYETFLAFCTLKKPIKWGNE---MVQLICFFNIKKNNemdLQVLYEFLYTMINDKNIVEKLTNCRTVPEFSALLYS-- +>tr|A0A101E4V7|A0A101E4V7_9THEO PTS modulated transcriptional regulator, MtlR family OS=Caldanaerobacter subterraneus GN=XD49_1301 PE=4 SV=1 +------DLSIFQVKVKSKGEIILKLSEKLKEKGYVKDGFYESVIERESFSSTAIGNYVAIPHPYS---GFVAVPKIAVAVLDAPIKWDEAK--KVQLIFLIALDLSVredFKMIFEELSDVVENESKVQKLLKCRSFEEFVRIFRA-- +>tr|G3K4I1|G3K4I1_9LIST Putative PTS regulation protein OS=Listeria fleischmannii subsp. fleischmannii LU2006-1 PE=4 SV=1 +------KYFTILEGKRTKEQILTTLANKFEVEGNVQASFLKSVKERENIVATYLGNGLAAPHPIS---ADVKETKIAVCITKEPIIWNEEG-DEVQIILMLAVKNKEqeqLSTVYEIISQIVEIPKLAKEIREVEDFEAFIRILEY-- +>tr|F5WR13|F5WR13_ERYRF PTS modulated transcriptional regulator OS=Erysipelothrix rhusiopathiae (strain Fujisawa) GN=ERH_0136 PE=4 SV=1 +------KLFIANPDTQSPQELLELMSQKALNLGYIDKACQESIIEREVLGSTEVGNLVCIPHNIE---GSVYRPSIVVCVLDKPIPWKY-D--HVQLILMILIDQDHrthCSDLFAELYAEIDHQYKVSNIIKNKNIAYMKSLFIE-- +>tr|H3NM72|H3NM72_9FIRM Uncharacterized protein OS=Helcococcus kunzii ATCC 51366 GN=HMPREF9709_00433 PE=4 SV=1 +------ENIYPLLDFNKPKELLKFICNDLVLRSQVNKGIYESIIEREKISSSSIGNLIAIPHPLN---KMSEKTFWTIITLKDEIRWGD-N--NVRFVILLNVVNEDkmyLDTMYENLLKLINNKTYIDELLEINDSKIFYNRIKE-- +>tr|R9BZ94|R9BZ94_9BACI Transcriptional antiterminator OS=Bacillus nealsonii AAU1 GN=A499_19803 PE=4 SV=1 +------DLVQLEIDKDHPYEVIEMLGNLLFQKGLIEKEFIHSALNRERKSATAIGGNIAIPHGDP---EMVIQSAIAVAILKEPIQWGN-E--YAAVIFLLAISKQEqnlNRAVIGQIASYSENLEFSRRIAKLTDVKSVLDYIQ--- +>tr|A0A0B4S4B1|A0A0B4S4B1_9BACI Transcription antiterminator OS=Bacillus sp. WP8 GN=QR42_01365 PE=4 SV=1 +------RLTLMNADLSSKDEVLNILCSRLEAHQLVSSSFRPSVLEREQMSSTYLGSGIAMPHPLI---TNEGTSSVAIAHLKQPIDWQG-D--QVSIVFLLAIHKDDaacMNQFFEQAVDLLDNPDRIRALKQAKTFDELMDAFFQ-- +>tr|A0A0R1MGL0|A0A0R1MGL0_9LACO Uncharacterized protein OS=Lactobacillus capillatus DSM 19910 GN=FC81_GL001785 PE=4 SV=1 +------KHIFIQQKFSNKREVLHFLSNQLISQHLVEKDYENLLLQRESFASTYFGNLTAIPHPVH---MVTKKTFWTICTLERPLTWDKAG-HQVQFICLMNIKKGEknnLEQMYQRLLAFLEDKELVRKVVKANTKSEVIKLLGE-- +>tr|I7KLE5|I7KLE5_9STAP Uncharacterized protein OS=Staphylococcus equorum subsp. equorum Mu2 GN=SEQMU2_13600 PE=4 SV=1 +--------------------------------------------------------------------------------------MGD-K--DVQLVFYLGLKSQTtvdMEPIFKRISHIINDFSLVVELLNQSNEKDLKETYFD-- +>tr|A0A1B7KS79|A0A1B7KS79_GEOTM Uncharacterized protein OS=Geobacillus thermoglucosidasius GN=A7K69_08430 PE=4 SV=1 +------ELFFPEIDKKDPIDIIKSMTYILNIKGYVDDSFLDSVLEREEISPTSIGNLVAIPHPVK---PNALNSCVAIGIMKKPVKWGEH---HVQLVLLLALNEKDkdkYSDLFNQLWLLVQDKKLVADLCKSSDFAQFIKRLEK-- +>tr|A0A1D8GCK1|A0A1D8GCK1_9CLOT Uncharacterized protein OS=Geosporobacter ferrireducens GN=Gferi_02855 PE=4 SV=1 +------QFFYLKDTFENEFEAISFMAEKLQEAKIVPANYKALVIERELIASTSFGNLVALPHAVE---LNAFQTVFSVAILKKPMRWGT-H--KVQLILMSAVKRGErkmLNELINHIAAILDDSKAVNNLVMSSNFDSFKHNITR-- +>tr|A0A1F9ZPM1|A0A1F9ZPM1_9FIRM Uncharacterized protein OS=Firmicutes bacterium GWF2_51_9 GN=A2Y20_03765 PE=4 SV=1 +------EDIHLMVDLKTKEDILSFMARHLSAKNHVTEDYLDSLWEREAMGPTVISSLIAIPHGTF---ETVLRSTVQVVTLAHPVLWDD-E--HEVRLILNVAStKEEasdYIPFFTHLADHSEDLDLWNRICAMRNKEDLAQALSE-- +>tr|A0A1E5H9I7|A0A1E5H9I7_9ENTE Uncharacterized protein OS=Enterococcus ureilyticus GN=BCR24_06980 PE=4 SV=1 +------EHFKRNIYLNSPSLYIEHLGRQLVEADYIDPHFIELIKDREKMSATSFNNSVALPHAIE---MSAKKTGIAIVLNDRPIKWEN-Q--DVQVIIMIVMNQKDmkkFRQLFDFMIDTFSNRAKLNRLLNVTHYEGFIEELFT-- +>tr|A0A109UHE4|A0A109UHE4_9FIRM Uncharacterized protein OS=Erysipelothrix larvae GN=AOC36_08310 PE=4 SV=1 +------SISVFDEKVQDQNDAISILSNIMFKQGFVDHEYRDSCLLREELSSTFIGNMVAIPHAYH---GHVLNQGIGLLVSKKPFDWNG-A--KVQLVFALAIDLKSsqdFGDIANEIITLVNQVDVLDKLFQTKDLRSFKKFIK--- +>tr|A0A1M4SPV4|A0A1M4SPV4_9FIRM Transcriptional antiterminator OS=Alkalibacter saccharofermentans DSM 14828 GN=SAMN02746064_00334 PE=4 SV=1 +-----------------------VLQPSDDDKGYAAEGFIESILIREKKSSTYIGKGLAIPHSKT---EFVKKSKIAVIRLKRLMVYKH-E--MIDTIFILCIKMEGydmAANVFGQFYEMLDDDSQIAELKKAYTPQKINEVLRR-- +>tr|A0A1T5J7E7|A0A1T5J7E7_9CLOT Lichenan operon transcriptional antiterminator OS=Maledivibacter halophilus GN=SAMN02194393_00973 PE=4 SV=1 +------ELFFTDIQFESKEKVLDFLTSQMVDKGYIGKDIKKSILDREKLSSTAIGNLVAIPHALQ---VVEVPSCVCIGILDKPIVWDQNK--KVQLVMVLSISKNIsyrFTDMFGTLYQVTKSPLSVEELINQNDFDKFHIKFLS-- +>tr|A0A1T5KCP2|A0A1T5KCP2_9CLOT Lichenan operon transcriptional antiterminator OS=Maledivibacter halophilus GN=SAMN02194393_01687 PE=4 SV=1 +------ELFMISEEADTKDEIINIVANNLKDKKYAGDDFLPKVYERENVSSTALSEMVAIPHPVR---ACALKTGIAVCINKKGVCWDETK--KVHIMLMLAIKPKEykyMDGIFDLIVKILENDCITMKLLNCKSYEEFLKELKD-- +>tr|A0A1T4PYR0|A0A1T4PYR0_9BACT Transcriptional antiterminator OS=Anaerorhabdus furcosa GN=SAMN02745191_2227 PE=4 SV=1 +---------ILKCDYTNQEILFEEVEKKLKSKHYIEEGFKEDLKHRESKCSTSIGAYTAIPHANP---QFVKKSVICVVTLQKPMNWGS-E--EVDVFFFLAITKSDfssINIKLRNLYKLLYSETFHKQLLDAEKQDQVLKLVDI-- +>tr|A0A242HNS0|A0A242HNS0_9ENTE Uncharacterized protein OS=Enterococcus sp. 12E11_DIV0728 GN=A5865_001256 PE=4 SV=1 +------CVLLPNQSLSTPREIIDVFCTALSERVSLPDDFTDQVERRETLSTTEVGNQVALPHPCE---YDGEKNLLAVMSLKKPVRWKY-N--NVRLVILQAIPPYEnndAIQFQEDVTRLVCDQKAVTRLVRNLNFDTLQFELFG-- +>tr|A0A010Z078|A0A010Z078_9CLOT PTS system protein IIC component, Fru family OS=Clostridium sp. ASBs410 GN=K413DRAFT_2695 PE=4 SV=1 +------KLIKVNMQAGDKNAAIEELAELLYKEHVLKdkAIYIQNVLEREAQVPTNLENGVALPHGKSD---AVLRPAVAIGISKRGIRFEEG-SPVSHIIFLIAMPnnaDDTHITLLSGITSRLLDCDCLDYLKEAKRPEDILAALST-- +>tr|A0A0U3ECB8|A0A0U3ECB8_9MOLU Uncharacterized protein OS=Mycoplasma sp. (ex Biomphalaria glabrata) GN=ASO20_02945 PE=4 SV=1 +------HVIRI--DVSSQNELFEKIADNLHEHQVfSCdkNIIINAYKEREEQGTTNLGEGFAFPHILIN---KIKVPTILIVQLENEIMYGDSNIDLAI---VLAFPktmeGGEHLRVISKYSEKLLDEKFLKNLRKAKPAQLKKELTDF-- +>tr|I9DN41|I9DN41_9FIRM Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Pelosinus fermentans JBW45 GN=JBW_02581 PE=4 SV=1 +------SLIELHMKSKSKTEIIETLAHKAKELGYISEveGYLQDVFALDESSPISFGYGIAIPYGKSR---YVLTPFIAFARSEEAFTWDHRVDHEARLIFLIGvpeeQDDDFDVKMLTHMIGGLTNESFRRRLLQTSDAAEVVELFKE-- +>tr|A0A1L8REV5|A0A1L8REV5_ENTAV Uncharacterized protein OS=Enterococcus avium GN=RU95_GL002651 PE=4 SV=1 +--------------------------DQLIKNEQERSNYKDEINESlEQFGPYYLl-PNVILFHGKPDK--K-YSNALVIVKLNKAFTAVED-NLPVKLIVGMTAEdSNAHLKVLQHLVEKLNVYQNVVDILSAKKKEEIEKVIH--- +>tr|A0A1F9ZRT5|A0A1F9ZRT5_9FIRM Uncharacterized protein OS=Firmicutes bacterium GWF2_51_9 GN=A2Y20_06395 PE=4 SV=1 +------KLILTGLNHLDRNEILNLACDRLESLGRVKSGFRKSVFHREQTIPTCLGNGIAIPHGKEE---FVLTSSIMILCCDHDVDWGNGSARLMFLIAVNFTGETDTKEVLTDLYNVIDTPMLIQQLKNARNADEVLALFA--- +>tr|A0A1M6K9T5|A0A1M6K9T5_9CLOT Transcriptional antiterminator OS=Clostridium caminithermale DSM 15212 GN=SAMN02745912_00341 PE=4 SV=1 +------EIFYRSKKFKHPNQIIIEMCENLEKKQYVKREFMESTLAREKIMATEVGNGIAIPHGDPK---EVIKSCIALTILENPLKWKKEMVKYVFLICIAEKDVAKTKTIFRNLYRSMDKPEFLNGLKKNRKFVKrMLDQLE--- +>tr|A0A1L6AFW0|A0A1L6AFW0_BORGR PTS fructose transporter subunit IIA OS=Borreliella garinii GN=BLA33_02260 PE=4 SV=1 +-----KDLVFILPEANSKEDVIDFLVEKVNDKGYIDskKEFLQGILDREKIGDTSWENGVAIPHFIGDV---VKTSFISLLYIkGTGVKWS-EENPPVNLIFLICMSkkqqGNEHIKSIAFIAKLFEDDAFKNALSGIVTADDIYYYMEN-- +>tr|D1ARV2|D1ARV2_SEBTE PTS modulated transcriptional regulator, MtlR family OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_3754 PE +---LPKENIKVVNSVKNWQEAMEISGRILVDNGYTEWEYVESVIDMVYKHGTYmvLKKNFILGHGNY--LEKVRKAGLSFLYIKEGVEFPENH--FINCVITLCSRDkKEHTFGLLELHRVIENCDLYKKISEKNSGDEVYREI---- +>tr|H1PQP4|H1PQP4_9FUSO Uncharacterized protein OS=Fusobacterium ulcerans 12-1B GN=HMPREF0402_00737 PE=4 SV=1 +---ISMSRIEKREKADSWEEAIKMSGEKLLHENIVSEGYLDEIIDLINKFGSYmvIQEGIILSHARG--NESVSKTGISILLLDEPVEFPENE--KVKLLITLASKDkREHLNGLMEFINTLREVKLLDTLENCQTISEIYITF---- +>tr|D1AHU1|D1AHU1_SEBTE Transcriptional antiterminator, BglG OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_1463 PE=4 SV=1 +---LKEENIIFEkKKLEKWEDAVKEGFKPLEKGKYVDESYYKSIIELINNFGSYmvVSEGLAIPHAEN--MNNVHKSGISLLYLKHPVIFPGNK--KVNLLFCLSAVDkKDHVQSLEDIIRLEEEFSFRKKMAETNSKEEITEIL---- +>tr|D1AHL2|D1AHL2_SEBTE Transcriptional antiterminator, BglG OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_1382 PE=4 SV=1 +---LGKENIYTNLTFDSWENALYFGGEVLEQKGAVSPDYVESIINILKTHGSYmvINEHILLAHGRN--EDNVFETSMILMTLKDYIEFPNDK--KIKIIILFSSRDnQEHLNALLKLTELLDERDLYNQIKDLETSGEIYEKI---- +>tr|C6JIT2|C6JIT2_FUSVA PRD domain protein OS=Fusobacterium varium ATCC 27725 GN=FVAG_01233 PE=4 SV=1 +---LSEKRIKLKGKAIDWRGAIREAGELLLRDECIEEEYIENMIKLVDDFGNYimLIPNVIFPHTKS--KDLVKKTAFSIVTYDKRIDFLDEG--KIGIVICFCVKDeREHLDSLIEIVEKIEENNLEEKIRKSKTAKDVIKYL---- +>tr|A0A1E9JK47|A0A1E9JK47_9FUSO Uncharacterized protein OS=Fusobacterium sp. HMSC073F01 GN=HMPREF2747_07540 PE=4 SV=1 +---LKKENILLNEKIIEWKKVIKKGMEILIKNGSVNHDYEKKLLYSVERYGSYltIYSNVCFAYSKD--KSEVRKSDVVFIELEKSINFPGNE--SINKVFVVSAINeREYLIIAENILDILTEGRLEDIINKKIK------------ +>tr|A0A0X8KAZ7|A0A0X8KAZ7_9FIRM PTS ascorbate transporter subunit IIA OS=Selenomonas sp. oral taxon 136 GN=AXE86_06280 PE=4 SV=1 +-----EDLVLFDVEAADREELLTKLANVLREKGYVKDSYPQAILEREAAYPTGLntkGVAIAMPHAAAA---HAVEAAILVARLKHPVTFKEmggtGKDVPARLVFMLSIDDpEGHVIMLGKFMSIFCDEGKLVDLYETNDPKAVVEKLSK-- +>tr|A0A174HFV7|A0A174HFV7_9FIRM PTS system galactitol-specific transporter subunit IIA OS=Faecalicatena contorta GN=ERS852491_03134 PE=4 SV=1 +-----KEMILTGIKARNAEDIMRRLCDRAMQMNCIEPVFVTALLEREKEYPTGLptGVPIAIPHIHDG----CLRSFFSMAVLDTPVAFGCmgdpDETVETRLVFLFGITDpSYQTAVLRKFSNIFQDDGIMNELLEIDKPEAMIQKMKE-- +>tr|A0A224WY92|A0A224WY92_9LACT Uncharacterized protein OS=Lactococcus sp. Rs-Y01 GN=RsY01_701 PE=4 SV=1 +-----------DKQYLNKNQALEEISRNLIHNGFVSDEFVQDILERENDPdiSTDLPTGVSIPHGNPA---FVNKTGIFFIRNHKPIFWGKHAVKMI-IVLCIAQKDHHKINgILSDLYSIVESKKAIEMIYQFKNIDDFSSL---S- +>tr|A0A099IBH3|A0A099IBH3_CLOIN Uncharacterized protein OS=Clostridium innocuum GN=CIAN88_02695 PE=4 SV=1 +--------CILLKKDvQSKEDALHMLADCLNEEAYITDssAFLKDIHKREEEFCTYVGHETAIPHAIS---ACVSKAGIAFLRSDKAFQYGSSDET-VKLLfmLAIPKDsNEQHLRMLSALATKLMHKEFREQLLHAKSISDVYEILML-- +>tr|I4B5D2|I4B5D2_TURPD PTS system IIA component, Fru family OS=Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) GN=Turpa_1842 PE= +----TEANihiisaqNPGNFDlt--DKWTLLNGLRKALCER--eqvsaeLCAEIEHELLAREKLMSTGIGEQMAIPHAVIAGACKLM---TQCAILPEGIEFESIDGSKAHIVVMLVApksALQAHLKVMASIAKVFYRAEARAKVIASKTPAEALAAIMS-- +>tr|A0A1V6G051|A0A1V6G051_9BACT PTS system fructose-specific EIIABC component OS=Planctomycetes bacterium ADurb.Bin069 GN=fruA_4 PE=4 SV=1 +----SPERIVWLSSc--DRGEVLSELARLHTSFDTtiALEEVRRALVEREQLNSTGIGQGLALPHARIPKVQDFS---VILGLHKGGIDFNSFDGEPVHLFLLIIGpttANDRYIQILARASRFLRAKAA--DILAAATADEIYAMTLD-- +>tr|A0A1V5XZZ2|A0A1V5XZZ2_9BACT Mannitol-specific phosphotransferase enzyme IIA component OS=candidate division BRC1 bacterium ADurb.Bin183 GN=mtlF PE=4 SV=1 +----AEGVILCPLEet--EKWAAIEECVQALPHV--asrkiDFASAMAAIREREAQeHSTILDNGVAIPHGILPDPAPLA---GALGVSPVGVSYGV-GARKAGLIFVIVGsrsVRREYLGILAQIARLFRGLDLKNKIMQAKLPGDVLQLIRD-- +>tr|A0A1V5YUN8|A0A1V5YUN8_9BACT PTS system fructose-specific EIIABC component OS=Candidatus Hydrogenedentes bacterium ADurb.Bin170 GN=fruA_2 PE=4 SV=1 +----EASQIRIIPAGATKHEALEILVEALCqNPAIQNKEVfTRAVHEREAIQTTGLGNGVAVPHVRIDEVSAPT---VALGIAPDGLDFQALDNRPVYIIVLFatpQDSGKTYLSLLAKVMVTLREEETFAALAACRTVEEVTSLLGI-- +>tr|A0A1V6G7I8|A0A1V6G7I8_9BACT PTS system fructose-specific EIIABC component OS=Planctomycetes bacterium ADurb.Bin069 GN=fruA_1 PE=4 SV=1 +----TDDLILADMKARDKRTAINEIVAFMCaRNGISEenaRKVEAAVLRREGRGTTGIGKGVAIPHAKNCgQVDEIV---AAFGVARGGVPFAALDGEPVRLVFLVvspRGLENDHLRVMRKIAHLARDDKTNRFLATTRDFSTLRAILDE-- +>tr|A0A1U9NLA8|A0A1U9NLA8_9BACT EIIABC-Fru OS=Phycisphaerae bacterium ST-NAGAB-D1 GN=fruA_1 PE=4 SV=1 +----VDKACIGFMDKCSKQAALNSLVDLIGkSKDVSDvDEVRTAIFHRETLMSTGIGLGLAFPHARLSSVKKPA---MAVGLCREGIdDYESLDNAAVHLVFMIvagKDQHAQYLRLLASISKKLKVENVRKSLINAPDEDSFYALLKE-- +>tr|A0A1Z8ZQW2|A0A1Z8ZQW2_9BACT Uncharacterized protein OS=Verrucomicrobiaceae bacterium TMED86 GN=CBC46_11400 PE=4 SV=1 +----SPECIILQLDKTEHEEVVLEMIGHLAeigkIASKDCYRYSQAVMERESQTGTGLGAGIAIPHARVPGLKEEV---AVYGRSEEGVDFESPDQGLAHHVCLLlvpEDGASNHLKILRELAKVFSQADLRKKIRSAQSAEEISELLCI-- +>tr|F4PFZ3|F4PFZ3_BATDJ Putative uncharacterized protein OS=Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) GN=BATDEDRAFT_93283 PE=4 SV=1 +---LTEDMIHFTSESLDWHHAISMAAKPLVNAESVEERYVDAMIKNVEEIGTYihVGKGIAIPHARPE--EGVNKIGELGVTGvevSHSDLSSATPQDADVFFLAKDIAEGgSHLGEVVVLDSIIDMDELRTKVKQVLEEKNLI------- +>tr|A0A161YB42|A0A161YB42_9ACTN PTS fructose transporter subunit IIA OS=Propionibacterium avidum GN=A2U93_08065 PE=4 SV=1 +------ELTNVNAEAADRDQVLTAMAHQLDESGVTNAGFLEALLKREENYPTGLpiSGGVAIPHTDPQYVTrdavavTTLRTPVLFGQMG-----GSeEDEVSVSVVILMALSNaDDHLSMLQNIVKSIQNGDLMQRIRsA-TKPEEiv--SIV---- +>tr|M4ZC53|M4ZC53_STREQ Putative PTS system, galactitol-specific IIA component OS=Streptococcus dysgalactiae subsp. equisimilis RE378 GN=GGS_0293 PE=4 +------EVVCLqVDNIKNAEQALAYLGNQLVATGAVKDSYVKAVIDREAIFPTGLqfeDYGVAIPHTDSEHVNhtqlalMTLTEPVSFTQMA-----TNDQPVSVRLIIMLAIKDsHEQVDMLQKLITLLQNPDVVHDLLaYGPDQKEsvlqLLSRH---- +>tr|D1AWN1|D1AWN1_STRM9 Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Streptobacillus moniliformis (strain ATCC 14647 / DSM 12112 / NCTC 10 +------KVFFENLEVSNKNELFEFIVENLVKLERIEKPqrILQKFHEKESELTTFLGSKFAIPHLKS---TKVLENTIVFIRLKNPLIWNEEGD-MAKYICAVLVKPrydDLYIDILMSLSRNIIDSNKANILKHSENKEEVLMLLN--- +>tr|A0A0E3UUA7|A0A0E3UUA7_9FUSO Uncharacterized protein OS=Sneathia amnii GN=VC03_00745 PE=4 SV=1 +------DTTLIDIDIKDKIDLFTKITKISKEKGYISDEqgVIEDFYAKEQNTETYLGTECAIPHARS---SRILKNVIFFVRVKNSIKWSDED--NAKFIFAILAKEndvDKHIDMLMAVSKKVLDPKVLDVLRKSNSREEILDILC--- +>tr|D1AVN5|D1AVN5_STRM9 Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Streptobacillus moniliformis (strain ATCC 14647 / DSM 12112 / NCTC 10 +------DNIIINSNKINKENIIENMISSL--NLDIEISenIKNEIMIREKIDNTVLGFGFAIPHCKS---KYINESKVVYLKSLTNIIWDKEEE-PVNHVFMILVPEnnvGEHIDILKDISSKIIDKNFRNKLNILEDKIEIEKILN--- +>tr|I8IZ25|I8IZ25_9BACI Pts modulated transcriptional regulator, mtlr family protein OS=Fictibacillus macauensis ZFHKF-1 GN=A374_13655 PE=4 SV=1 +------TLVFIESKPCTRESIIKEQATAMQQQGYVMEGYLESVLQREQQSSTAAGGEIAIPHGNPS---FVFRTVLAITVMRTPMQWGTTS---VSLVMQLAARKEDHhqlQALFKEIFQLTENLQWIRTLQQAEDTKALYALF---- +>tr|A0A1I6U8S4|A0A1I6U8S4_9BACL Activator of the mannose operon, transcriptional antiterminator OS=Marininema halotolerans GN=SAMN05444972_11457 PE=4 SV=1 +------ERLFLQLENMERDQVLRLLADALVQAGFVDHAYVESVLKREHLSSTAIGGGVAIPHGALH---HIHHPGIAVATLKEPIQWEGEP---IHTIFLLALLPEERdrsQRIFRELVDLSADAARLDKLQTLQNPYMWIQQL---- +>tr|A0A0R2ILJ7|A0A0R2ILJ7_9LACO LicABCH operon regulator OS=Pediococcus cellicola GN=IV80_GL001815 PE=4 SV=1 +----NSQLIFFAKKTETRAAVIKNIGKQLQKLGYGKNGIIEAALNREKLASTAID-NIAMPHAPIE---FVLKPCIAIYINPQGIMWEGNK---VNIVFFLAMNreVQNKIEQIYKrFNDILENKKLLKELVGCTNAQVVLKKLGS-- +>tr|A0A0R2CYD2|A0A0R2CYD2_9LACO PRD domain protein OS=Lactobacillus rennini DSM 20253 GN=FC24_GL001921 PE=4 SV=1 +----RPDLVFKVAAAGGYRQVITKIAHQLFVNGYITdqEKVIQAAISREKLASTALD-QFALPHVSPN---LIKRPAIVLLVSQQPINWLGDqQ---VHFVFFMALNstVHQSLREIYRlINQIIDDHQLAKRLLQVEKAPQLIQVLND-- +>tr|S2PHP1|S2PHP1_LACPA Sorbitol operon transcription regulator OS=Lactobacillus paracasei subsp. paracasei Lpp123 GN=Lpp123_09916 PE=4 SV=1 +----SPTRILVSSKHLERDDAIKMIGQLLVDRDLAKIGVAESAIAREEVASTLIRQdQVAMPHAQSE---YIKKSGITLLVATHGVTWGDGE---AKFVFFIGLNqhAikNTNLDAVYHrFNQLVSSDDALSLLAKANNPKAIWHQLID-- +>tr|C2K0D8|C2K0D8_LACRH HTH domain protein OS=Lactobacillus rhamnosus LMS2-1 GN=HMPREF0539_2623 PE=4 SV=1 +----EPALIVPNLPSTDRETALSTLIQRLTQAGVFEdaSLPLKLAEDREKLATTAMG-LVAMPHISPE---MVRRPAIALGLAPDGLDWAGQK---VKVIFFLAVTatVPGDQRGIYQvINRLIDDQRFCEVLAQSQSTTEAVKALAE-- +>tr|A0A0R2E0N3|A0A0R2E0N3_9LACO LicABCH operon regulator OS=Lactobacillus mali KCTC 3596 = DSM 20444 GN=FD00_GL000666 PE=4 SV=1 +----SLNQIYVNEQLSNANQVISFLGKELINKEFAKSGVIESALEREEISSTVIK-NMAVPHSKVK---YIIKPSISILLNKNGIEWGNKK---VYLVFFIGLNnsVIEKSKEIYKyFSKLIYPE-FIKKACKCNSSEEIYELIMR-- +>tr|A0A0F4LLC3|A0A0F4LLC3_9LACO PRD domain protein OS=Lactobacillus kimbladii GN=JF75_04320 PE=4 SV=1 +----SPETIFIGNL-SSQKDVIKYLGNKLIELGYADPEIIGSINSREKMASTALAKlNIAIPHPEPG---TVRKTNIAIYIPKHEIKWGKSK---VNLIFLMSYKkaDinVLPFDDIYHgFNLMVSSDELRVKLLSSKTKQEAYKSIYQ-- +>tr|K9ICZ1|K9ICZ1_9LACO PTS system transporter subunit IIAB OS=Pediococcus lolii NGRI 0510Q GN=PLO_1788 PE=4 SV=1 +----DTQLIQIDSVKKSYVTVLEEIVGSLTKQNILVnnPKILEMLVEREKMASTALN-AVAIPHIAPN---YVQKSAIALWLVPQGVQWLGNT---VYVVIFLALTreQVAASREVYKiLNRMVENTAFCQQLAQVATVSKAMEHIQK-- +>tr|F6IUV1|F6IUV1_LACPE Transcription regulator, mannitol operon OS=Lactobacillus pentosus MP-10 GN=LPE_01384 PE=4 SV=1 +----SPNGIITNSSATNKQAAIIQITDQLQTHGYVDKQMQASALAREQVASTIID-KFAIPHGDIN---HVLKPTIGILTSKRGIEWDHER---VHIVFFVALNrtVESQMDDIYSyFYSLIQNANRMAALTKAQDVQSIIEILAH-- +>tr|A0A0R1KCN9|A0A0R1KCN9_9LACO Uncharacterized protein OS=Lactobacillus alimentarius DSM 20249 GN=FC67_GL000169 PE=4 SV=1 +----DPRLIIFtEEKDSNYKSALLKLIEQTIKYGYSDDELYDSAIIREKLSSTATD-GMALPHGTTN---HIKKPFIGIIKSKQGIDWLGEs----VHIAFFMGLKgiDATSMKNIYHqLNNIVENKKIISNLINCDDKKKFFTYL---- +>tr|A0A0R1SYW8|A0A0R1SYW8_9LACO Transcription regulator, mannitol operon OS=Lactobacillus saerimneri DSM 16049 GN=FC54_GL001655 PE=4 SV=1 +----KRKNILFvDDPTLTPEQAITKIVNNLKQAGYVHEGMLETALKREEQSSTELR-NAAIPHGDPR---LVIIPSISILLNRSGMQWGKNh----IKAVFFIAVNeqLDSELDRLYQhFYLLVRDNQAIERIAQAHSAEEVLKIIDT-- +>tr|A0A0R2CFN9|A0A0R2CFN9_9LACO LicABCH operon regulator OS=Lactobacillus cacaonum DSM 21116 GN=FC80_GL001470 PE=4 SV=1 +----TLDNIIIKNKPVTFEDAVTEISKIAGKKKISNIGLKEAILEREKISSTFYD-EVGLPHATKE---NVKQSAVFVFISEKGIYKEYEK---VNVLFFLLLAddAKHFINEFYEfLNDIVTNKKKIKKIIKATTKAEVIHELES-- +>tr|A0A0R1GWQ5|A0A0R1GWQ5_9LACO LicABCH operon regulator OS=Lactobacillus bifermentans DSM 20003 GN=FC07_GL000227 PE=4 SV=1 +----DPTAIYWRSDLPDAPAAIRFLGQQLIQRGLATEGVLVSTLSREIFSSTVVR-QTAMPAAQVN---EVLQPSLSMLIAPKGINWYGQS---VQVVFFLALDhsAQAVLPEIYQgLTQLKTTA-FVKQLVKCTDAAAAYQLIQQ-- +>tr|A0A1E9TVV4|A0A1E9TVV4_9LACT Uncharacterized protein OS=Aerococcus sp. HMSC062A02 GN=HMPREF2626_03290 PE=4 SV=1 +----DSDLFITsSTELDTQESVIAKLISKAEEKEFISADFKTSVLNREKLSSTAIG-RIAMPHGDYH---YVKQSAVMVYKNESGIKWDKDK---VYIVFMFMVNqeIKEHLSQIYSdFNALISSESTVNNLIKSQSYKEFKTIIRE-- +>tr|F4BSP5|F4BSP5_CARS1 PTS family L-ascorbate (L-asc) porter component IIA OS=Carnobacterium sp. (strain 17-4) GN=ulaC PE=4 SV=1 +----SENHIKVIDYVENWKQAVEIASEPLIKENLISHIYVENMISSVqDNGPYMvLTDYFALMHAKP--GEGVNQQSMSLLVTRNEIDLEG---KPVKIFLILAAEdSQSHLKGLQDVIAIFMDKNKYQTILNGQKK-DIIELF---- +>tr|R2QBR0|R2QBR0_9ENTE Uncharacterized protein OS=Enterococcus pallens ATCC BAA-351 GN=UAU_02548 PE=4 SV=1 +-----ENRITIVDEVADYKEALQRAGQPLLTEGAVTEEYIQAVIDSHDFEDPYtiLGQEVAIPHALPSE--GVNKIGISLLIVRQGFRYSQSHS--LKIVFMIAPIDkKQHNQAIIDILTIAESPEMIEKLTNTTEKHAILTLLK--- +>tr|A0A142KJS4|A0A142KJS4_9ACTN PTS fructose transporter subunit IIA OS=Propionibacterium acidipropionici GN=AXH35_13835 PE=4 SV=1 +----APRFLVLDADTANQEDLYSVVNSHLLSQEAVHETFLEAVSARELKYPTGLdfGhCQVAIPHIDP---EHIITPGVLVCRNAQPTPFHAMDDPErtldVRLTIWPLVTdPQNQTGMLGAVIALLQEETSYQRLLTE-SPEKLEELLAG-- +>tr|F2N8J5|F2N8J5_CORGP Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Coriobacterium glomerans (strain ATCC 49209 / DSM 20642 / JCM 10262 / +----HTDLIILDAEVASAEEAIRLMGDRLEKLGFVTEGYADMVCDREKTYPTGLpgAsWAIALPHTDP---TLVIRPAVGVIVPREPVEFKMMGAPDttldVRLIMPLVIKdANSQLSLLKTMMGVIADAQLLERIRRSRDPREIIELLRP-- +>tr|A0A0F4LYD5|A0A0F4LYD5_9LACO PTS Gat IIA OS=Lactobacillus mellifer GN=JG30_00430 PE=4 SV=1 +----DPSLIFTDINLTTQTDLFRFMADVLQQKKYIEKPFLKAVIQREAQFPTGMqlQgCGVAIPHTDP---QFIKRSFIFFVRPQQPLLFHKMEDPQqtlnVSFVLLLGLDnSGNHLKILQRLMTMFQKQTLIQQLLSSANNAAICDLLKN-- +>tr|A0A140DVS0|A0A140DVS0_9FIRM Uncharacterized protein OS=Faecalibaculum rodentium GN=AALO17_16130 PE=4 SV=1 +----DTSLVFLDADFSSRDDLFHTMGSWLKDNGYVNEDYREAVCRREEEFPTGLkvPgHQLAIPHTDS---EYIEKPGLVFVRPKNPLAFQEMCSGDpvdAEMIFLLLVKdKKDQMPLLSGLMARFGDGELMDRLSRETDPEVIADLLDH-- +>tr|R2QKC5|R2QKC5_9ENTE Uncharacterized protein OS=Enterococcus malodoratus ATCC 43197 GN=UAI_04404 PE=4 SV=1 +----EEKNILLNQSFSNQEEYFQKITKKLMTENMVKEGYFESITKREITYPTGLyiGeQSIAIPHTDY---QLSNVTAILVSVLKDSLPFQRMDDPEetvsVNVIIQLLFDsPDKQPQLLKELMNKVTNQDFLQAILGAKSKTEVLTAFNK-- +>tr|A0A1F1W487|A0A1F1W487_9MICO Uncharacterized protein OS=Dermabacter sp. HMSC06F07 GN=HMPREF3157_08995 PE=4 SV=1 +----RPRLYVLDVPKGEgtsFASLTRFVASHLEADGCVTSSWVGAVLAREQLYPTGLplEPPVAIPHADT---THTLKDALVVARLAEPLAFGAMGDSDagalqVRLAVFIVAGnGMAQVEALERLLSILGDGARRERLEAG-SAENARRSFEA-- +>tr|E3G412|E3G412_ENTLS Transcriptional antiterminator, BglG OS=Enterobacter lignolyticus (strain SCF1) GN=Entcl_4261 PE=4 SV=1 +----GETHVRLAAeLPASWQEAISDASSSLLCDAVIEPRYVRIMTDKISEEQPwiMLAEGVIIAHAGID--DGAADTGMALLRLPEKMDFAGYM--QADIVIVLATHNPqKHLKALAQLNEFLEFHDGGNCIRQARNKTELLNAIAI-- +>tr|A0A239V8A7|A0A239V8A7_LISWE Mannitol-specific cryptic phosphotransferase enzyme IIA component OS=Listeria welshimeri GN=cmtB_1 PE=4 SV=1 +----SSNMTRVVKSVPNWHTAIELTAAPLLEAGFIDQTYVNAMKSLYPEIAPyiVLKGNILLPHARPE--DGVNKFGLSILKVEDGLIFNGK---KIHLLVVLAPVDKkKHLTAMFQLLTIASNQQVIDKLKNATSGTAICQIFKE-- +>tr|X1ES49|X1ES49_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S03H2_15833 PE=4 SV=1 +-----PELMNFDVVPGDKMKILGQLTFPMIQSKFLTrrKYFLDRLIERENMMTTGLGNGVAVPHPRQPIPNLFPESAIAIGICKEGTDFDADDGKTVYAFLTVCSSDDvHHLRILARIAKFASDKSATKKLIKARIPEEIIDILK--- +>tr|G0GDZ4|G0GDZ4_SPITZ Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Spirochaeta thermophila (strain ATCC 700085 / DSM 6578 / Z-1203) GN=S +-----PECVLTGFSATREEEAFQKMVDAAFRAGRVKdpEELVRLVLIRERQCSTVMRPGVAFPHPRAVGPEVVPEYALVLAISPEGVPFSDAPGDgDVHFIALFAIPSLqLHLKILAALGELFSHEEVQERLLSARSPQEVISHIT--- +>tr|A0A1G1J4J5|A0A1G1J4J5_9BACT Uncharacterized protein OS=Omnitrophica bacterium RBG_13_46_9 GN=A2Z72_00480 PE=4 SV=1 +-----ESCINMDMKSRKPDGILYELAEIAQESGIAVsiENLLIQLKKREQMLSTAIGKGVAIPPPRNPSDELFRKTGLIIGRSAKGLDFDAPDGKKVHLFFMTCATDVvLHLNLLSKIARLLDADGFIKRMIRVKSKKDIMKLLL--- +>tr|A0A1W9VNX7|A0A1W9VNX7_9SPIO Uncharacterized protein OS=Spirochaetaceae bacterium 4572_7 GN=B6229_07005 PE=4 SV=1 +-----EKSIITDLKGQTTKEVIHELAEKAYINEFVAdkNIFIKQLLEREQLTSTSIGQGIALPHLRKPNGNIVTEPKIVIGVSKEGIDFDSLDGEKTTLFLLLLSDSEvVHLKLLSKITRIFGIDNAISQIKQLRKPEEFVKFFN--- +>tr|A0A0H4KJR1|A0A0H4KJR1_9BACI Uncharacterized protein OS=Bacillus endophyticus GN=BEH_10860 PE=4 SV=1 +-----RNLIFTNLDMTSKDEVIEFVSASLQKRGYVRDQFYESVKNREQKASTDLGNKVAIPHGEN---QFVQKSCIAVVTLKEPIKWGRSEVSIV-FFIVLKVENKQSmRPILRELYQVLDSKRILQMMERASCEDDILHILGGK- +>tr|A0A0D0GAA6|A0A0D0GAA6_9BACI Uncharacterized protein OS=Bacillus thermoamylovorans GN=B4166_1376 PE=4 SV=1 +-----PNSIFVNNHFNSMKEILEYLISYLEHEDLVTPLYRKSVFDREATSSTALETGVAIPHGNP---DYVKKTSISILVNSKKVHWGNEKVDII-ILLSVAKNDVNHiSSIISQIYDVISDRNRMETVFFGKTKENIYEYFYDH- +>tr|E7G876|E7G876_9FIRM Uncharacterized protein OS=Coprobacillus sp. 29_1 GN=HMPREF9488_00964 PE=4 SV=1 +-----EKMIFWDMEFKNKDECLKFVMEKLYSAGYVKEGFEKSILEREKIGTTALDSGVAIPHASI---EYTRETKIVIVNLKHKILWNDKKIDVV-ALININQKDKANvRNLLGELYQFIRERKDVEKYFKMNTKDEFIKSINQ-- +>tr|A0A1L8WKN4|A0A1L8WKN4_9ENTE Uncharacterized protein OS=Enterococcus pallens GN=RV10_GL002828 PE=4 SV=1 +-----EEVIFLNETITSKEQCIRKITKALLQADLVTESFEQAIWDREKLGATDLPTGVAIPHPAP---STVKESKLVIMTVAKPIRWNLRMINTV-LMICVAEKDLKDiKGILSEIYRIVESKRNVDKTILGKTKQELMSILGGE- +>tr|A0A1L8TBZ5|A0A1L8TBZ5_9ENTE Uncharacterized protein OS=Enterococcus gilvus GN=RV02_GL000719 PE=4 SV=1 +-----VAYIYTKKHFSDKQTCLNWLIDKLEKGEIVTRGFRKEVFDRETIGETALATGVAIPHASP---QNVLQTKIVIVTLTKPITWDKRKVHSI-LLMCIAKSDRTLvRGVMTDIHKIVQSEKQLKSIFGDREAVEIYNDIIGR- +>tr|A0A1Q2C4U3|A0A1Q2C4U3_ANAHA PRD domain protein OS=Anaerostipes hadrus GN=DO83_03100 PE=4 SV=1 +-----GKFIFLKQDLDSKEKCLDFIIDVLEKDNAVYDEFREAIYKREKLGVTCLDTGVALPHADP---QTIKKSRIILLTLKHPVDWGGTLVSLI-VVTAFPEEEMNQiRDVINELYQLIGEKEDVNAFIRFETIQEVLKVFHES- +>tr|A0A0Q3QQY1|A0A0Q3QQY1_9BACI Uncharacterized protein OS=Bacillus solani GN=AN957_17115 PE=4 SV=1 +-----SRYMFINEEVETKEDCLNKMIQRLEEDQIVKSSFKKSVYEREKLGNTIVQGWAAIPHAMS---TMANETKISIMKTKQPIKwNHETYVSFI-ILLAVAEEDLNQvRSLLAHLYKIIINSDRLGsghSFKSMTTPDDLIAFLLCK- +>tr|A0A1L8QQQ2|A0A1L8QQQ2_9ENTE Uncharacterized protein OS=Enterococcus aquimarinus GN=RU93_GL000482 PE=4 SV=1 +-----KEFVYIDTDFSTKEELLNSVGKELVSNNYVTENFVTSLISREELGGTDLPAGVAVPHGNP---SDVKRTTIAIVKNKKKFKWDTYYVDVI-FVIGISYENRADtRKILSDIYNIIDTSKKLEDIKQAQCKEDLFIKLGSE- +>tr|A0A1T4P0Z1|A0A1T4P0Z1_9BACT Transcriptional antiterminator OS=Anaerorhabdus furcosa GN=SAMN02745191_1833 PE=4 SV=1 +-----PDFIFHNKKFKTKNECLDYLIKIYQKRKYVNEEFAESIYEREKMGDTSMYTGAAIPHASP---ETVLKSQISVVTLKDKIKWGSQDVNLI-VFIAVAKDDMDRiKNVLSKLLDILESTQTIEKMVHASNKEILVEILEES- +>tr|A0A1T5L0L9|A0A1T5L0L9_9CLOT Transcriptional antiterminator OS=Maledivibacter halophilus GN=SAMN02194393_02268 PE=4 SV=1 +-----LKHIYMENDFKTKEECLDYLFQNLYEDDCVDKKFRDDIYERESLGSTYLSLGVSFPHAMP---TYVRKSAISVLLLPNGVFwDEHRVY-LV-IMLAIKSDEIKEtIKDLPVLYKKVLDYQFINNLVRLNEPEDIKKMLLE-- +>tr|A0A242NUC9|A0A242NUC9_9GAMM Uncharacterized protein OS=Gilliamella sp. A-4-12 GN=B6D06_07445 PE=4 SV=1 +-----ADLIELNVDIQHKSDCLNLLISKLEDKGLVTKNYRDSVLYREEIGDTSIENGIALPHGSP---MFVIKSSISIMTLKRPIKWGMIDVSII-IMVSLSEDNINSiNDVFTEIYEIVSNKQAISSLKNLINFKQLKQFLDNQ- +>tr|A0A219BEI1|A0A219BEI1_ENTHR Transcriptional regulator ManR OS=Enterococcus hirae 81-15-F4 GN=F522_01960 PE=4 SV=1 +-----DGWMFLNQDFDSRESVLSFITEKYKEEQLVKDNFLEVVLQREKLGATGLSSGVAIPHANP---KYVVKTKISIITLKNKITWGDVDVRVV-LFLAIAEEDMIQvKNMIALLYDVFVSPERIKSIASKETRNEIINEIIGK- +>tr|A0A213I727|A0A213I727_STREE PRD domain/PTS system IIA domain-containing protein OS=Streptococcus pneumoniae GN=licR_4 PE=4 SV=1 +-----LETIFLRKEFKNKEGLIEYVGNSLNKNKFVDYSYLESIFAREAIGITALEYGVALPHASS---KTVNRTHIAICTLSHPIDWDGIPTSLV-IFMNFEDDEVENiRYIVDKIYKKINSKEKVDKLVGCKKPEELIEEIRSI- +>tr|C2K0U1|C2K0U1_LACRH PRD domain protein OS=Lactobacillus rhamnosus LMS2-1 GN=HMPREF0539_2776 PE=4 SV=1 +-----EEDIQLGVKVDTPEEAIRIAAKPLKAKGAINQHYVEKMISPDDgHSLDAyiISPGVALPHTDPKN--GAQRVAIGITTLEKPVFFSQAKSEKVKFIFVLSAVNPtDHLMVLQDLMDLLGDANFMKLLADkKTDSRKVMQYLR--- +>tr|A0A140DYU9|A0A140DYU9_9FIRM Uncharacterized protein OS=Faecalibaculum rodentium GN=AALO17_26920 PE=4 SV=1 +-----PGLIRTHVQCETRPEAVRIAYAPLQERGMITEEYIRRTIAGMDLAGPYvvIAPHTALLHTAAEH--GARQQGLSLTVFETPVVFGSPENDPVKYAYALSVPQgTpSHLTAMAGLLKLLEDPGFADICDTHD-PRRIWDSIC--- +>tr|L2Q8C9|L2Q8C9_ENTFC Uncharacterized protein OS=Enterococcus faecium EnGen0038 GN=OKI_04765 PE=4 SV=1 +-----KAFIQFHLPATTYAQAVQQSAAPLLAERVLTENYLAEIIHSAAERKSWmmITDGVALPHTKPMY--GANAIGLSLGVLETPILLENG--REMRYIMVLSAIDNhQHLKAIAQLVHFLEDGAFFELLQTTDSQEKVFAYIV--- +>tr|A0A0W7V275|A0A0W7V275_9STRE Transcription antiterminator BglG OS=Streptococcus gallolyticus GN=AU078_05260 PE=4 SV=1 +-----IKFIQTNVEISDYEEGICKAAKPLLQSGIIQNQYLEKLIDD-YHKGVImrLTSLFCMPHATDT---GGNNLGMSLVVLKHPFIFKDK--SSVKYILLLSAPKSsVHLLAMNQLLKLLGQENFYEALDNF-SPKDIYHYIL--- +>tr|A0A173WPL2|A0A173WPL2_RUMGN Probable licABCH operon regulator OS=Ruminococcus gnavus GN=licR PE=4 SV=1 +---LDETIILLQKKYKSMEECVKEVCAILEKDGCIEDGFYDSVISRERIAPTNIVDGIALPHGLNK---YVKENRIAIVTLKKPISWGNDRVSTIF-LVAINFSNIMVSkKALEELYFCISDEDFISELKSCMDVKEVYQLFETV- +>tr|H1BPJ2|H1BPJ2_9FIRM Uncharacterized protein OS=Eubacterium sp. 3_1_31 GN=HMPREF0984_02241 PE=4 SV=1 +---LDKETLLLKQDYEDKDTVLEKIHTIFMRNGYVSEGFLASMKERERMAPTEMGNGLAIPHGISK---YVKKEKILVMTLKKPIVWDKEKVDIII-CLAFNFADKERSrKLISNIYQFIKSKDTIHRVRECTTEKAFYEIVRSL- +>tr|T4N853|T4N853_CLODI PRD domain protein OS=Peptoclostridium difficile P28 GN=QSI_4338 PE=4 SV=1 +---LHEKNIYINDGKITKDEIIHQVCMGLNKEGCVDAHFETSVWEREQKGGTDIAVGGAIPHGAVS---TVRKTQLALWINKEPVKWSKYRVKVIV-FFALNSEDTAKTkVILEEAFSLIKTKEMIEKLSSMKNKKAVIKYIFGG- +>tr|A0A1G8BAF3|A0A1G8BAF3_9MICO PTS system IIA component, Gat family OS=Agrococcus jejuensis GN=SAMN04489720_0806 PE=4 SV=1 +------DACMVGVVAADAVGVLRQIADLAIRAGHAAPSFGEALVTRERAHPTGLPTlvPVAIPHADPS---HVLEAGFAVATLARPVSFGVMGTaddHvDLDVVIVLLVTEaHAQVEVLASLVDMVQRDGWDASLRAARTPAELAASFD--- +>tr|A0A1L8XB69|A0A1L8XB69_9ENTE Uncharacterized protein OS=Enterococcus saccharolyticus GN=RV16_GL001442 PE=4 SV=1 +-----SKSILIEENQVTWHEALDALSQPLISEKIITPQYLTALKQEMAEIPpyMIFRNRLALPHTEPE--KGALGVAMSFGIFKEGFLTETDE--RIHIVVLLASNdKEKHIDALLELMDLSGRDDYISKLVECQTAAQAYKILH--- +>tr|A0A1L4C0S3|A0A1L4C0S3_9LACT Uncharacterized protein OS=Marinilactibacillus sp. 15R GN=BKP56_10695 PE=4 SV=1 +-----TSMIRIVDKVSDWQEAMKVAAQPLLETGKISSQYLKALNNQYPVVSehIVLQRNIAIPHAESE--KGVKELGMSMLFIKEGIPNFDGS--DLHFIVVIAATdRKSHFTALMELMKLAGNDALLKELSKSGNEDEIYQVIL--- +>tr|A0A1L8WAK5|A0A1L8WAK5_9ENTE Uncharacterized protein OS=Enterococcus pallens GN=RV10_GL002085 PE=4 SV=1 +-----PESIILLDEEESWGSVLQKTTQNLIERDIVEPRYLTSLQEQFPVVKpnILLGNSIVIPHTVPE--NGTKNLGMCFAKVKQGFQS-GEQ--RFYYVVAISAVdKKQHIQPMMELLKIASDSKMLDKLAAADSKEEILALIA--- +>tr|A0A1V9S9N8|A0A1V9S9N8_9LACO Uncharacterized protein OS=Lactobacillus salivarius GN=B6U49_08195 PE=4 SV=1 +-----PNFINVIEKIDNWDSMIELGCKPLLENNAINNNFISNLKNNINNILdyATLAKRIALPHLGKI--DGAKKIAMSLVLCRNGIKDKKGN--KYYIVVFLSAPeKIGHLKAMKQLMMIAKNDELYSKLIKCKNGDEVYKKIY--- +>tr|A0A1T4LYQ0|A0A1T4LYQ0_9ENTE Transcriptional antiterminator OS=Pilibacter termitis GN=SAMN02745116_00869 PE=4 SV=1 +-----DMSIQIFQN-ESWQEVVQSLGNILIEKKIIAQRYIDEVLRQYTEITpqIALRETIALPHVASE--FEVYGTGLAMGIVKEGICFKKTQ--SIYLVILFATNtKEAIAETMLELVQLSGQTEVIEKLKKSTNAKEARGYLE--- +>tr|A0A0S4V7T5|A0A0S4V7T5_RALSL PTS system, glucose-specific IIA component OS=Ralstonia solanacearum GN=RUN1985_v1_620050 PE=3 SV=1 +-------------------VLAPLSGRVVPIEDVPDPAFAQK----------MVGDGLSIDPATD-----------VVLAPIDGrvIDFHDAR-----HAIVIADASGVEIMVHVGLDTVMLAGQGFEALVGKGDTVRAGQPL---- +>tr|A0A1Z4SF75|A0A1Z4SF75_9NOSO Phosphoenolpyruvate-protein phosphotransferase OS=Nostoc sp. NIES-4103 GN=NIES4103_59140 PE=3 SV=1 +-----------------------------------------------------------------MV-------GIVIV-------SHSKQ-----LalgVQELAAqmvQGNVPLAVAAGIDDA-------ENPLGTDPmqvYEAIASVF---- +>tr|A0A1A5WVY9|A0A1A5WVY9_9BACI Uncharacterized protein OS=Bacillus sp. WF146 GN=A6764_19795 PE=4 SV=1 +--------IIVTEEVVGREQILTQLGGRLVQSGAVADEYVPTILEREQQFPTGIeleSIHIAIPHA---DAAYVRKPAVAMAVVKKGVSFRSMAdpeKDLpVKIVIMLALeKSETQLRVLEQIMSFIQHADRLQELVEMESGEAVFRALK--- +>tr|A0A1L8TAT7|A0A1L8TAT7_9ENTE Uncharacterized protein OS=Enterococcus gilvus GN=RV02_GL000987 PE=4 SV=1 +--------HGLISEETDRDQLIHLLAAEMAKYGMVEPCYGASVLEREKEFPTGVptmPVPIAIPHS---ERSQVYKPGIGVAVLRNSVKFSSMEdptCLLdVRVVFMLAAsLNDEHLHMIKDVMEIIQDSEVVNALLAAETTKEIEAIMH--- +>tr|A0A212J6Q2|A0A212J6Q2_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=uncultured Clostridiales bacterium GN=KL86CLO1_10598 P +---LNEDGILLSASVANKEEAINMLISGPHRFGVLAdAAtCHADVLVRESQGTTALPGGIAIPHAKSRG---VASLGVNVLTVPGGVDFGAADGSKSRLVFLLVGPEHdpsGYLEMLSSLLKLFTKNDQlVERLVAAKTSGEFLSIL---- +>tr|A8RD41|A8RD41_9FIRM PRD domain protein OS=[Eubacterium] dolichum DSM 3991 GN=EUBDOL_01582 PE=4 SV=1 +--------------YATGEEAILDICSKLQQKHCVNESYAQEVMEREALSSTAF-GGFALPHS---LHMNCLRTTIYVHIQEKGIIWGKQT---IHVIFLLSVSKQERkmfREIFEYITDIINDAEKFSKIRKAKTYEEFIHLFLA-- +>tr|H1BB73|H1BB73_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium 6_1_45 GN=HMPREF0981_02456 PE=4 SV=1 +--------------LKVKEDILHFMCEHLEAEGYTDSSYYDRVMEREAMSCTVF-GKTAVPHA---LKACAKHSGICVYTSDHGILWEGRQ---VYIILLIAIHPEDQlrfNEFFNKITERLCEDDKTARLISCVSYEEFLEALVY-- +>tr|A0A099I3S5|A0A099I3S5_CLOIN Uncharacterized protein OS=Clostridium innocuum GN=CIAN88_17880 PE=4 SV=1 +--------------FSSASACIRAMCAKLQRHGFADERLFDEIMEREHMSSTAF-DHFAIPHS---TYMRSKKTIINILISKKPILWNSNQ---VSIVILMCFNKHDRalfQSVYETISAVLIERENVKKLTACNSYDEFIETFVS-- +>tr|A0A1T4XQU7|A0A1T4XQU7_9FIRM Lichenan operon transcriptional antiterminator OS=Gemmiger formicilis GN=SAMN02745178_02180 PE=4 SV=1 +--------------CTTREEVVHHMCSRLLALGCTTPAFEAAVMERESISSTAF-GQFAIPHT---LKMCSPRTCMAVYVSRTPICWDDTA---VNLVIMLSFNPNDRkifYDIFEPLSMILLDSNNLKGALLCRDYTAFIDFLVE-- +>tr|A0A1S8YKQ1|A0A1S8YKQ1_9ENTR Uncharacterized protein OS=Izhakiella sp. D4N98 GN=BTJ39_13245 PE=4 SV=1 +--------------FSNENQAIEFMAQALNQQGYVDENFIQDVFQREHSYPTTF-GSIAVPHS---MKMDAIKTGLCVAISEKPFPWGDNM---VNMALMFSINKAERaifYDIFDNIIVLLLEPANLKKALECRSWKEFIVTITT-- +>tr|D1APG6|D1APG6_SEBTE Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_3159 +---LDKKYIFLHRDFGNKEDVFHFINGILLEDGYVTEEYLPKVLERENTFPTGMElekINVAIPHIDSK---YILKENLFVITSKKGIEFNNAENNgeklNVKIIFGLLIREhNTHINFLVKLIELFQENDKLEQILESSDKDEVIKILKD-- +>tr|A0A1M6DMT1|A0A1M6DMT1_9FIRM PTS system, galactitol-specific IIA component OS=Propionispora hippei DSM 15287 GN=SAMN02745170_00935 PE=4 SV=1 +---VYPELIWVNKSFADKEDLFKTVAQSLYNKNFVTETYYESLLAREIKFPTGLDmedYYVAIPHSECG---NIKKEFISVVVLEKPVTMNKMDDPqielPVEYVFFLGMNNdQDHLKVLKEVITIIQNKHLILEMKKTSSPDQIAGLLTK-- +>tr|L1Q7J5|L1Q7J5_ANAHA PRD domain protein OS=Anaerostipes hadrus DSM 3319 GN=HMPREF0369_00714 PE=4 SV=1 +---LEDPYIRIIKDKFKWQDAIKVSGEVLLENKLIRQSYIDSIIYKTDQYGPymFITKQVFLAHSEIE--DGAQSMGLSMTIFKKPVEFITldGKQRFAKIILMLSAQDQkSHIRLLNDIMTIFSEQKNEEKLWGQKEILDVKNVLYEL- +>tr|D3AR09|D3AR09_9CLOT PTS system, Lactose/Cellobiose specific IIB subunit OS=Hungatella hathewayi DSM 13479 GN=CLOSTHATH_06065 PE=4 SV=1 +---LTEDRILFLDRngrerteekrewsgdgySTGWERALYTAASPLLERGSMSEEYVRCIVDRMVEAGPymFITRDLILAHARPE--NGVKHLDLSIGIAADGIEFEGG--KTARVIFCLVVEDQqKHMGILQDIRKTLAKPRQIDELVRAESAYEVCDILRSR- +>tr|A0A0V8QCQ4|A0A0V8QCQ4_9FIRM Transcriptional antiterminator OS=Acetivibrio ethanolgignens GN=ASU35_13220 PE=4 SV=1 +---LKKNRVQILEGHFQWQEAVRCAGKSLVEAGSIEKRYLEKIISQILYYGPfmFLNQGLVLAHAKPE--DGVNYMDVALTVFKEPVAFSEY--HYAKIIITLAVEDQeRHLGILKDIMAVFGEERHTEELALLASSEEILKYMQQY- +>tr|A0A1L8REV6|A0A1L8REV6_ENTAV Uncharacterized protein OS=Enterococcus avium GN=RU95_GL002650 PE=4 SV=1 +---IGQHNIQIAATPLGWREAVAMAAEPLRATKTIDQEYVEEMIRLVDVYGPyiVLGKNVALAHAKPE--NGVNRLGISMLVCPEGIYFDEE--NEINVLFVVASPNEyEHLNYLNDILKFAKNSDAVKSIIQTKNVTECYELAKGM- +>tr|A0A0Q1AP08|A0A0Q1AP08_9BACT Uncharacterized protein OS=Candidatus Cloacimonas sp. SDB GN=APR54_07580 PE=4 SV=1 +----KLECCDIDFKAQDKNDALLKLAALLKHNdslkDTSQEKIFRSLKEREEMGSTGFGKGIAIPHCRLEGLNeFVIGLAV----CSKGVNFDSLDRKKTKLFVTIvgpLEDRSGHLQLLAKVSLILKDNIVVENLLKAKTKIGLYEEFF--- +>tr|K2QAI0|K2QAI0_9LACT PTS system, fructose-specific enzyme II, BC component OS=Lactococcus garvieae DCC43 GN=C426_2087 PE=4 SV=1 +----NPNNVFFAEENFENNEsLFHFIAKKAKDLDYVQseEECFQGLVERESQSTTAFQDSFAIPHCK---SDTVKQPQLLFIKS-SAIKWESLDGSDIEHSFALLIpstGAKEHLKYLAQIARSLIDDNFRHEIKASASPKEAYNIIK--- +>tr|A0A0R2LBS1|A0A0R2LBS1_9LACO Galactitol pts, eiia OS=Lactobacillus pobuzihii GN=IV66_GL001689 PE=4 SV=1 +-----KKLIFYDVDAVDRKDLYKKISDELVKKGFVKESFYQALNAREDEFPTGIVtkhLPIALPHANPEN---VNKPFIAVVHTKKQIQIqqmGTNEEEKTKNFffLGIVE-EtqDLQVKLLQRFMEIMNDQNFVEQFVTIKNPETIYDFLIN-- +>tr|F0EJG2|F0EJG2_ENTCA Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Enterococcus casseliflavus ATCC 12755 GN=HMPREF9087_11 +-----EELIILNLDSADRTELFKQMAKIFNDKGYVKEKFYDFIVEREENYPTGLDlgtHKVAIPHGDPEY---INHSFISVVTLKRPIKIkkmEDADEEIdVDLFfiLGLSD-GTQHLQILKQVIGLIQQEAFVKAIQSATSAKEVMEKISA-- +>tr|A0A1H4LX82|A0A1H4LX82_9ACTN PTS system IIA component, Gat family OS=Atopobium minutum GN=SAMN04489746_1004 PE=4 SV=1 +-----PELVFFDFEATDYVDFFQKFSQIMMEKGYVKDSWCAAITERERTYATGLLfenLPVAIPHVDPQH---IIKPYIAIIKPKTSISFepmAGmVDHPIdTKLIvnLGLLKHAEGQVEVLQAMMGMFMDDNAVADILSQTTAEGMVDCFKR-- +>tr|A0A242JX10|A0A242JX10_9ENTE Uncharacterized protein OS=Enterococcus sp. 9E7_DIV0242 GN=A5888_004053 PE=4 SV=1 +-----EDLIFIGQELRDRAELFKWFNGCMIEQGFVNESYYESILKREQQFPTGIQtptVGVAIPHADPDN---LNKPFIAVVRPKRGIEFepmGIAEGNIqAELIfmLGVLK-NGDQVIALQKLMNLLTNNEAVQQLLEVRTCKEMMEIIRV-- +>tr|J3TRJ7|J3TRJ7_MYCGL PTS system fructose-specific enzyme EIIABC component OS=Mycoplasma gallisepticum WI01_2001.043-13-2P GN=fruA PE=4 SV=1 +-----PEFVFINLKQKNRDDILKELATRAVKLNLATnqDELYQAFLAREKESSTALPDLFGIPHARTAT---VKQPALLFAKLHQAVEWDEEK-KQVQYLFVILVPqdaSNTHLEIISNVAKLIMDKNANQKLISSNNPDEISKLIVS-- +>tr|A0A0C5X205|A0A0C5X205_9MOLU PTS fructose transporter subunit IIABC OS=Mycoplasma dispar GN=MDIS_02795 PE=4 SV=1 +-----KDFVFLLQNLKTKDEVFEFIAKQSLKLNIATdeKQIIKDLQNRESQIPTGLESGFAIPHTQSES---VLKPALFFISLKDGIDWQTFDNSLAKYLFCILLPkngfDEAQVNVLAKIASLILDPKVKEI-LKSTEVDFVFANLAK-- +>tr|A0A1S9CRS5|A0A1S9CRS5_9FIRM Uncharacterized protein OS=Epulopiscium sp. Nele67-Bin004 GN=ATN35_01655 PE=4 SV=1 +-----EDLVFINADFSDKKDFVEKAAEALAKKKLCTdkDAFVKDVFAREEQGDTDLpEEGVAIPHAKSSA---IKKPKIVAATLSKPWAHPDS-DNGISMVFLLAMPknaADDHISVLSSLSTLLLDENEVKALRAAKSPKEFIKLMHV-- +>tr|A0A1F4U8B4|A0A1F4U8B4_9BACT Uncharacterized protein OS=candidate division WOR-3 bacterium RBG_13_43_14 GN=A2Y85_05180 PE=4 SV=1 +-----KDRVNLMIKPGKKNKVIEDLVFLIKKG-SDAELIVSTLMKREELGSTGIGKSIAIPHCRSLAVD---KLEIAVGRTTKEINYNAIDKKPVSLIFLIIAPpqdpGNQYLLTLGKIVQIAKELTKKDLVFKPQTPEEFIILIGQ-- +>tr|A0A1G0XBA6|A0A1G0XBA6_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_45_14 GN=A2020_00055 PE=4 SV=1 +-----KES-VLILEGLNKRDVINEILNAAEKVsPIARDIMDKAIWQREKMMTTGLGHHLGMPHIRHSKLG---EPILLVGVCKNEItDYASVDNLPIRVIVFLAAPegdQENYLKLLGSISSKFRDEtLIAEILENIDKPSKILTLLKK-- +>tr|A0A235BZM1|A0A235BZM1_9BACT Uncharacterized protein OS=candidate division WOR-3 bacterium JGI_Cruoil_03_44_89 GN=CH333_00330 PE=4 SV=1 +-----KGRFKNHLRSREKRQAVKELFETTDQP----PPVLQRIYAREREFPTGIGCGVAIPRYLGKEVK---EATLSLGLSRGGIEFGTLDRKPVKIIWLLIFPeheRKKYTEILVRLIRLANTEEFRSQVLNVASVEELVELIKD-- +>tr|A0A1L8WCP9|A0A1L8WCP9_9ENTE Uncharacterized protein OS=Enterococcus pallens GN=RV10_GL001307 PE=4 SV=1 +-----EQLVWIQQDFTSREALFSFMSQQLYEKGYVNEGYQEEIISREEKFPTGLvleNYNVGIPHCDSQYVKkdfiaiVILSNYIQMNQMDK----PDNEIPVKYLFFLGLQDANNHLKILKKIMKVIKSEQLIHRAENSQSVKEISELLK--- +>tr|A0A0K9GSZ3|A0A0K9GSZ3_9BACI Uncharacterized protein OS=Bacillus loiseleuriae GN=AC625_09460 PE=4 SV=1 +-----DNLVFLDKEYKDFEDVLSHVMKTLINENYAEKDFEEALLIREKEFPTGLqldGYAVAIPHGGSQYVKqdfismVTLKNPIFMNRMDN----PEESLAIDILFIIGFGKSDTHLQCLKQLMGLIQDPKVIEDLRKGTSIMSVL------- +>tr|A0A242CWK7|A0A242CWK7_9ENTE Uncharacterized protein OS=Enterococcus sp. 3H8_DIV0648 GN=A5875_003762 PE=4 SV=1 +-----LENIKLNQQYKNREDYLKKMGEQLLSAGLVNEGYSTSIINREEIYPTGLatgEINIAIPHTDYQFSRttdifiTVLKTPIAFFRMDE----PEKTVEVSIIVQILFDNPEKQPDILKELMEIITNQRVLKEMIAAQEPKEVLQHFQ--- +>tr|A0A0A8E7M8|A0A0A8E7M8_MYCFL PTS system fructose-specific IIABC component OS=Mycoplasma flocculare ATCC 27399 GN=fruA PE=4 SV=1 +-----HDTIFLDKNFDSKDKALQFLSQELKNKMYISDAiqAKKLFQKREIQSSTGIGQAIAMPHIG---DDVVLKNTIMFVR-TTNLDWNAIDNLPIKYIFAIVLskneRDNSHLEIIQKLSQLLINPKFVTNLETIKTAQEFLNLID--- +>tr|Q98R81|Q98R81_MYCPU PTS SYSTEM, FRUCTOSE-SPECIFIC IIABC COMPONENT (EIIABC-FRU) (FRUCTOSE-PERMEASE IIABC COMPONENT)(PHOSPHOTRANSFERASE ENZYME II, AB +-----KNFIYFNKEFKDKNQALKFFSNQLLTQGYAHEEkkVFDLFVQRENELSTGIGDSIALPHIR---SDVMKKSTLMFAK-VKDLNWDSLDGKNVKYIFVIAMskdeGQNSHLEVIAQLSKLLLNKDFINNLNSINEAEKFISLVD--- +>tr|S1M0A2|S1M0A2_9ESCH Uncharacterized protein OS=Escherichia sp. KTE159 GN=A31E_02769 PE=4 SV=1 +------DLVFLRQRFIDSDDFFHTVNEKLLAANLVTIDFLQNIRLREREYPTGLAlesFSIAIPHTDIKFIK---EPFVAFYQLAEEMPWNEMgaDENklKIKFIILLGlVDTSSHIDFLQNLITLFSTENHADWLSKTQSSHDATNYLNK-- +>tr|H3NDR6|H3NDR6_9LACT Uncharacterized protein OS=Dolosigranulum pigrum ATCC 51524 GN=HMPREF9703_00697 PE=4 SV=1 +------NLVNIENKSTSLIDFFESASRELVEENFVEESFFEAILSREQIYPTGLVlenINIAIPHTDVDHIK---KPFIYINKMEDDIEFTQMgsDDKkvIPEYVIILGiKEPKKQVTLLSTLIELFNNSNFLDELQNCNNNDDLIKLFKN-- +>tr|V9HN81|V9HN81_9FUSO Uncharacterized protein OS=Fusobacterium ulcerans ATCC 49185 GN=FUAG_00208 PE=4 SV=1 +---INMKNIKVMEEISSFEEGIKIAGEMLIESGYITEDYIKSCIKAFNdqGAYMIIGGNTVLPHSD--NFKSVIKTGYSFLKLKKPIIVEQDDENllNIENIILLASSDgKNHRNSLLDLKNMIDKYKLEKSIHNCKTEKELLKKLT--- +>tr|D1ARA3|D1ARA3_SEBTE PTS modulated transcriptional regulator, MtlR family OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_3555 PE +---LTLGNIMVSDKKTDWIETVNTAGGILLKNGYINEGYIKNIIGNINknGVYMVLKNEFILLHAE--KQNNVFKTGIAFLRKKFPVEFPGK---yMVRNILAISCHSkEELSGSFEDILKLSENTGFLEELEDVRDSEAVFCLIK--- +>tr|C3WAJ1|C3WAJ1_FUSMR PRD domain protein OS=Fusobacterium mortiferum ATCC 9817 GN=FMAG_00440 PE=4 SV=1 +---LPAENIVITDEGFNWKNAIWKLGDLFIEKKLVSSSYIKDIIKIVEdnGAYMVVDERFGIFHAK--NNDNIFQTSLMLLVSKKQIQIKDK---KTHLILILASKDgHEHLQSLIEFSKIFESKENIDKILKLSSNKRIFDFIS--- +>tr|C3WF15|C3WF15_FUSMR PRD domain protein OS=Fusobacterium mortiferum ATCC 9817 GN=FMAG_02033 PE=4 SV=1 +---LPLKNIKLNLELKSWKEVIEKSGELLLKNQYINKKYIEEMKNKIIelGTYMVIDNKVLLPHGE--MKTNVLKTGISYIQLKNEVEFPGG---lPIKHIFALCTLNsEEHIKGLLELKELLEEKDLRIKLEKCFNEMEVISLLK--- +>tr|D1AVN6|D1AVN6_STRM9 PTS modulated transcriptional regulator, MtlR family OS=Streptobacillus moniliformis (strain ATCC 14647 / DSM 12112 / NCTC 1065 +---LSSENIKLNASARNIDEALKIAVNLMVENQIVEKEYYNNIKQQIDkyGKYIQIGNMSILPHGK--IDDRVKKTGFVLVTLKDEIDFFGA---KIRIIIMLASKNkEEHLDAILDINKCLKKYNFEEELLKISNKEEISKFLK--- +>tr|C3W9R0|C3W9R0_FUSMR PTS system, Lactose/Cellobiose specific IIB subunit OS=Fusobacterium mortiferum ATCC 9817 GN=FMAG_00159 PE=4 SV=1 +---IEPFLINEIDKVDSIEEAIKICASPLFEYKYVDNSYITSLIKTSTtpkNTNIYIGEHTIFPHCS--NKNNVFDTKFSFLKLKEPIIFKNK---KCKLIICFCTNQkNIYHNFLFKLFELIEKEEEEFYK---LPLSEYYDYLN--- +>tr|A0A1T4K790|A0A1T4K790_9FUSO Transcriptional antiterminator OS=Cetobacterium ceti GN=SAMN02745174_00355 PE=4 SV=1 +---LDKNSIVRMEKISSWEEGIKIAGNILMEKGAIKETYIDGMIETIKkyGSYMVLAPGIVFPHAR--TEENVIKSSFGILQLDEGVLFPGN---kLIKTIVAFSSRDnKEHIEAFVEIVEIFNGQNFSMDNF--INKIQ--------- +>tr|F0Z0M1|F0Z0M1_9CLOT PTS system, galactitol-specific IIA component OS=Clostridium sp. D5 GN=HMPREF0240_02652 PE=4 SV=1 +-------KLIFNGLEGGFENMIYTAGEKLQELGIVKSSYPEAVIIREKEYPTGLegvHGNFAIPHTYSE---HCIGSALSIIRPPKPLEFVRMDdHSKsilCGLIVLLAIDKPeKQLSMLRKLMRAMQDVEIFHILESERSSKAVVETLR--- +>tr|R8XPL6|R8XPL6_ECOLX Galactitol-specific phosphotransferase enzyme IIA component OS=Escherichia coli KTE33 GN=WEW_01241 PE=4 SV=1 +-------FVRSDIFFANRREALTHIGNEMVAQGVVHDSWPQALIAREAEFPTGImleQHAIAIPHCEAI---HAKTSAIYLLRLADKINFQQADDDNevaVSLIIALIVENPqQQLKLLRCLFGKLQQPDVVETLINIPEVQ-LMEYFK--- +>tr|W7BEG0|W7BEG0_9LIST Phosphotransferase system fructose-specific component IIB OS=Listeria aquatica FSL S10-1188 GN=MAQA_02262 PE=4 SV=1 +----RNDLIFTDVQVSSQEECFEQLADIAVRSGLATNkkAVVSGFEAREKESTTGMEHGIAIPHTEL---AEIAKPALIIMKLADGVEWNSLDDSETRLVLAMLIPkggAHGHLAILSEISKLLVHESFINELMQAKTKNEIEQLFKEK- +>tr|V6IX49|V6IX49_9BACL PTS fructose transporter subunit IIABC OS=Sporolactobacillus laevolacticus DSM 442 GN=P343_13245 PE=4 SV=1 +----KKENIYFEKDINTKDKLFQFIAENTYKNGVIEDraKLIEAFQKREEQGSTGMEGGFAIPHAQS---DTILEATMLVVKLADPIsDWQTFDQKPVSFVIAFLIPpkgSEAHLHYLSDTAAKLVNKNTVNQLIDAENADLIYDLLG--- +>tr|E3H875|E3H875_ILYPC Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Ilyobacter polytropus (strain DSM 2926 / CuHBu1) GN=Ilyop_1526 PE=4 S +------------LEAGNKEEAINNLADIIGEKGVVKDvhEVAHAIMAREKLASTSLGKGVAIPHCRTD---EVNETICVCGLIKNPVEWDSPDGkpvDIVFLVITPKEKPQEYLKVVRAIITTIKKLDLDGRVNHDLLRNILLT------ +>tr|A0A1V5XX12|A0A1V5XX12_9BACT PTS system fructose-specific EIIABC component OS=candidate division BRC1 bacterium ADurb.Bin183 GN=fruA_3 PE=4 SV=1 +------------FKIKSKGEAIWELIRSLHYAGHIHNpgEVLEIILKREHQGGTTLGDGISILHGRLP---YIKKPVVTMGLIPSDhkVNFGTAEDapvDIVYMVLSPQDKPEIHLQVLATLAMILSNQEARESLRHAKDEFEAFNVI---- +>tr|A0A1I0FWV2|A0A1I0FWV2_9FIRM Transcriptional antiterminator OS=[Clostridium] sphenoides JCM 1415 GN=SAMN02745906_0760 PE=4 SV=1 +-----ECRILVNQTYKNWQEAIDAAGGLLVATDCVLQSYVEDMINNIKEFGSYitIGNGIALPHARNKN--NVKKTAFSLITLKKPVVFDNGKE-I-DTVISfCNVAGNDYTTALTALMELSENQSFLDYKKKVETPSQLLDYIKK-- +>tr|A0A0R1UUJ1|A0A0R1UUJ1_9LACO Uncharacterized protein OS=Lactobacillus satsumensis DSM 16230 = JCM 12392 GN=FD50_GL002133 PE=4 SV=1 +-----KKLVFTDIAITDFIELIKWMSHQLYLMGYAKKGIAESAIKREQLSKTSFK-DYAVPHAQP---EFIMKPVVAVCILRQPIEWGANLVSI---VFFFGMTDTLSqKeidPIFDDFYKIVNSQRSLDSLIKAKTNHDLFIRLIGE- +>tr|A0A0R2HD20|A0A0R2HD20_PEDPE Uncharacterized protein OS=Pediococcus pentosaceus GN=IV86_GL000421 PE=4 SV=1 +-----SELVFLDKKLLTKEEVINFIGEQLVKLNYAKKGVSESALERERLSSTAFE-KYATPHAKA---EFINKSAIVFIRLKNEINWLGQNVRF---IFFICVKNETPNqldQIFDTLLEIIEENKEHkEHTLKNESPDNIVCYLKEG- +>tr|K2PSP3|K2PSP3_9LACT Transcription antiterminator, BglG family OS=Lactococcus garvieae DCC43 GN=C426_2091 PE=4 SV=1 +-----KEFIFLDEKINTIGQAILFLGQKLIAKGYAKEGFIESCLEREQLSFTSLD-SFSTPHPLnI---EEVNKPVIAFMRVKNELIWGKEKVKY---IFMMCVRDRSIKeleRIYSALLKIIDSPDQ--EILLRGNLDEIFDYLANN- +>tr|A0A1Y4F812|A0A1Y4F812_9FIRM Uncharacterized protein OS=Blautia sp. An249 GN=B5F53_05340 PE=4 SV=1 +-----EENVILDREAKTKEEVIRILTKHILTENGVTdeTEIVKAVAQREKLAFTGIGKRTALVHAVT---AGVKETKAVFLRTVSPVDWAKGKDYPEeakmiRIALLLLIpekeQRGEDVEKVKQLVLKLGKKENARRLLEVSTKQEVLKILNG-- +>tr|I0IBG4|I0IBG4_PHYMF Putative antiporter OS=Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01) GN=PSMK_04430 PE=4 SV=1 +----SEKLYVDELRTDNARGIIAELAERATATAGLPAaEIAESAWRRERLFSTGLPGGLAIPHARLA---GLSRPMVAVGRSRDGVDFDATDGSRARLICLLLSPAedpTAQVELLRAVGETFANKETRAAALDATGYTQFRAALIV-- +>tr|A0A168HYL4|A0A168HYL4_9BURK Uncharacterized protein OS=Pandoraea pnomenusa GN=A6P55_01740 PE=4 SV=1 +----EEKDFLPNVE-----RILVAVDGsangrFAAWIAGLTAgvrGTLTTVLAPSAAPTdgGRTAREVAEPARSPA---RPAKDKSAIGADEEGAGRDAYDIALAAAQIAIPAHRgppAsrttpAPIRRARPLASCYASAPARRRRRRRTCPTAPSRKAT--- +>tr|A0A0W8G8H2|A0A0W8G8H2_9ZZZZ Uncharacterized protein OS=hydrocarbon metagenome GN=ASZ90_000699 PE=4 SV=1 +----KAETFVSPLPATGPRRIVSLLTRTAARCAGLDEnAVLAEVRSREKRLSTALGRGVAAPHARIP---GLEHPVCAVGVVPEGVGMDSPDGLPVNVFFLVLSPQaddGAHLAILADIARAARMPHFASRAARTRSIEEFLRLLEG-- +>tr|E8RD94|E8RD94_DESPD Sodium/hydrogen exchanger OS=Desulfobulbus propionicus (strain ATCC 33891 / DSM 2032 / 1pr3) GN=Despr_0718 PE=4 SV=1 +----RFGLFLPELRADSIKGVIEEMTAVVGQVLGGRLepyVVSRVSCAPEDVACAAIVNDVLLLAAGVD---HISQPYVVTGLSTQGVGLSFMDTQRAHVVFLILSPKndpAIRGDMVAELSLLYRDQAMIDQTLQARSFTEFLALIRT-- +>tr|A6DSK5|A6DSK5_9BACT Probable Na/H antiporter OS=Lentisphaera araneosa HTCC2155 GN=LNTAR_21970 PE=4 SV=1 +----GRGAFVADLKHPAPAHVIKDMVLQLNIDHEVQADIIQSTISREQLMSTGLEKGLAVPHCRTD---LVKKPILLIGLHESGADFDCFDDGKAHVIALIITPLsdpESQLELISVLASHFSSKEEMVKAMTCKSKVDMQAILNA-- +>tr|I6ZT81|I6ZT81_MELRP Putative Na/H antiporter OS=Melioribacter roseus (strain JCM 17771 / P3M-2) GN=MROS_2022 PE=4 SV=1 +----KKEAVfIADDSISDKKELIRKLSAKVAEVHGLNKdLIFDEVWKREETISTGLENHLAAPHARCD----VKYPIAGLAVHKKGIDFDSLDGKPARLIILLITPKdkpELQLEMLSGIAQKLGKSDIIDYIINLNSKEEIIKTINR-- +>tr|U7VBW2|U7VBW2_9FUSO Uncharacterized protein OS=Cetobacterium somerae ATCC BAA-474 GN=HMPREF0202_01111 PE=4 SV=1 +----VYPGIK--LEAQYKEQAISKLLDLLK----LEYreaNILENVLDREDIVCSGLQNSIAIPKGNIE---DETKTKIIYARLENPINWNSLDGKLTKNIFLILTSReeqENQIKVVKKITNFSKKCDEIKGLDELATEKNIEDYITK-- +>tr|A0A1F6GDD9|A0A1F6GDD9_9PROT Uncharacterized protein OS=Candidatus Lambdaproteobacteria bacterium RIFOXYD2_FULL_50_16 GN=A2527_12300 PE=4 SV=1 +----SAKTFVPKMQVNDCWEAIELLSRVAALQAGLDPlEVIEAVKSREETMSTGVAKGLALPHGRLP---KLKKPIIALGICSQGVDFHSVDNTPAYLIILILNGSqdsGVQLRLLADAARIIKEVENLEEVKNITEFSELLHWLRI-- +>tr|A0A1J5FUT6|A0A1J5FUT6_9BACT Uncharacterized protein OS=Ignavibacteria bacterium CG2_30_36_16 GN=AUK34_00745 PE=4 SV=1 +----SPSNFlYSSAT--DKETLLIELANFAAPKVKIPAkEILQKVMEREKQGATGIANYLAIPHAKIK----TNKPYVLTAKIKEGINFGSVDGINSRIVILLLTPEnknELQLQLLAETAKKFSNKEKIEELLSIDDKNIFIEMLKQ-- +>tr|A0A1J4TUW5|A0A1J4TUW5_9BACT Uncharacterized protein OS=Ignavibacteria bacterium CG1_02_37_35 GN=AUJ54_14570 PE=4 SV=1 +----QERFVfFTNES--GKEKIISRLVEVASKELKLEKeVILREVMSREKNLPTGIANYLALPHAKIK----IKDPFIGIAINKRGVNFDAADGLPCKIIILLLTPEnnnEIQLQLLSEIAAKFRSKEQVEKLLALLNARELCAELKK-- +>tr|A0A1F5P5M2|A0A1F5P5M2_9BACT Uncharacterized protein OS=Candidatus Delongbacteria bacterium GWF2_40_14 GN=A2Y39_02215 PE=4 SV=1 +----MRDGIIPELLGTTKNDIIAELCSKVTPKLTG-LtcgEINTTVLEREKLMGTGMARGLAVPHARID---GLKNPVIAFGRSAPGVDWDSADGLPAHFIFMILLPAkdeSKQIQILAGIAKTISDPVYSENLLRMNDQERIYQSLKK-- +>tr|A0A1G0W9G7|A0A1G0W9G7_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_38_69 GN=A2X47_01805 PE=4 SV=1 +----SSDSVLNDLKAANREEAIKELCATVSGRLPGSLrnkCIAAAAISRENDFGTALGEGIAVPHIHLA---GLRHPILMVGCSRNGIDWNAPDGQLVKYIFFVLSPEgahDIHVQILSTIAKAMMKVQNKLEMDNSKDDSQLYDSLKK-- +>tr|A0A1G1LLX8|A0A1G1LLX8_9BACT Uncharacterized protein OS=Omnitrophica WOR_2 bacterium GWA2_47_8 GN=A2Z88_04395 PE=4 SV=1 +----AAKNVFLDVVGQTKEEVITNIASLLAERNIVQDenMIREAIWEREKLMTTAIGDGVAIPHARLP---NLKVPILGFFRLRHPVDFNSPDNKPVQIVFLELTDRdddGMQLNIVSQIAHFLASPHSIRRLLQCQREEDVYHVLSF-- +>tr|A0A1V5Q2C8|A0A1V5Q2C8_9BACT PTS system fructose-specific EIIABC component OS=Verrucomicrobia bacterium ADurb.Bin345 GN=fruA_4 PE=4 SV=1 +----PADALHLDLRARDRAGALRELCEVAALHTPG-LdlaAAHAAVAAREEAMGTSLGHGVAVPHARMD---ELKSAVVVSARSKEGIDWNAPDGQPAKLLFLVLTPThdaEMQIHILAKVAAALRTEEQRKALFEAPTPEVFYRALCR-- +>tr|A0A0T6Y7W4|A0A0T6Y7W4_9RHIZ Uncharacterized protein OS=Sinorhizobium sp. Sb3 GN=N183_28220 PE=4 SV=1 +----FENNLMLGVPAKDKRSVVQIIASHLALRtGMPFNVIFDGLMDREALGSTGFGDGFALPHALISDLSTPAR---VLVTLREPIDFDAaddEAVDIFVAVIWPQEQHDGFLQHLAKLCRLFRSKKLLVALRSARSETEASILISA-- +>tr|A0A1L3SUA0|A0A1L3SUA0_9RHIZ Uncharacterized protein OS=Mesorhizobium sp. B7 GN=BSQ44_17030 PE=4 SV=1 +----RPQDVLMRHPAQAKRPLLEAMARQLASRtGLTLVSVLSALLSREKLGATCIGQGIGMPHAMPGGLGEPAA---VLAVLEHPIPYDAsdeQCVDVVLGVVWPREGSTEFLNALARFCRHLSRPQVLKKVRAAMSAEEVLQHLGQ-- +>tr|A0A1Z2EZL6|A0A1Z2EZL6_LACCA PTS fructose transporter subunit IIA OS=Lactobacillus casei GN=BGL52_01435 PE=4 SV=1 +----VTTDVHtdVA-VPADKHAALGTIATILSTNrPISADELRDNLIAREDESSTGFGNGVAIPHAKVNGLTEPFV---GVVTFKQPVAWDSldgQPVSIAIVLVMPDQNgaDKLHLKMLSKLARKLMDDDFIKALKDAQHDGSQmTKVLDQ-- +>tr|A0A173VYL9|A0A173VYL9_9FIRM Probable licABCH operon regulator OS=[Ruminococcus] torques GN=licR_2 PE=4 SV=1 +----SEEFIIFEKKAKNRKDVLKRACQLLINKGIVQSEFARDVLEREKVEATAVGCNIAIPHGKP---EHVNRCQILVIRLDKPIEWGERMADMIF----LLAINFDSVNTtkafFHDFTKLLNENGATDRLREAASPHELCAAI---- +>tr|A0A1I0FIB3|A0A1I0FIB3_9FIRM Transcriptional antiterminator OS=[Clostridium] sphenoides JCM 1415 GN=SAMN02745906_0486 PE=4 SV=1 +----RPEFILLDVETVSKNKLIEIGFQVLRDYGCVTDRYYQEVLYRETISSTEIGNGVAIPHGIE---NSVLMPAVCMIRLKQKIDWGSAPVDIIF----MLALNFNDGETtrrfFKSFYEKAGNENIIRLLRTVRTEEEIMEIL---- +>tr|A0A099IAS6|A0A099IAS6_CLOIN Uncharacterized protein OS=Clostridium innocuum GN=CIAN88_05525 PE=4 SV=1 +--------LFYLYDTLNKEELLSKMCSHLLDLHYVAGNYYDAVLEREKYSSTYIGNHIAIPHAV---FPLAKKTTISICIMRNPVRWDNE--HEIRLVFLLSIKFSDsrYMSDLYNLFaEMVENSELAHKCIACTSYDEIIQLL---- +>tr|D2U2R6|D2U2R6_9GAMM Putative transcriptional regulator OS=Arsenophonus nasoniae GN=ARN_28930 PE=4 SV=1 +--------YFIILnEKISQEALFKKICKKLQADGYVTSDFYPSLIERESIVSTLLGEGIALPHSL---GLLANKTVVVTIISPQGIEWNAetK--EVANVIFLLAISKADyeEAIAIYELFvTFVKE-KATKRLINSRNFNDFQVIA---- +>tr|I0R2G5|I0R2G5_9MICO Uncharacterized protein OS=Candidatus Aquiluna sp. IMCC13023 GN=IMCC13023_05300 PE=4 SV=1 +---FGAGSIVAQDASPSFADAVSQSVSLLVASGKAQLSYVDEVLESLKTLGPYfvIAPGLALAHAK--PSDSVPAPGMALLKLAQPVISG-SANDPVSLVFSMCSPNaSEHMEMLADFGQIMSTDQVMTNLLNASAVSVIEDILF--- +>tr|R7G7I7|R7G7I7_9FIRM Putative phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Eubacterium dolichum CAG:375 GN=BN631_01564 PE +--------ICCNFRAKRRDDVLEKGAQMLHQQGYCTDNFYNILLHNENFVSTAIGNGVAIPHG---YKKEILRSGIAVIKLERPIDWDES--EKVELVFVLAIDldNPqEIYKFFSNFYVLIDDKERLEQIKLAENSKEVMAVIE--- +>tr|A0A1Q9JV28|A0A1Q9JV28_9FIRM PTS sugar transporter OS=Anaerostipes sp. 494a GN=BHF70_10670 PE=4 SV=1 +--------ILTDVMTATKKETIAEASKLLCQEGCLEEDVTEKVFELEERRPTTIGNQIAMAHV---YKEHVAESGIVLLKMKYPVQWSNT--SKVKLVFFIAINfeNSeEIVELFKFLYSLIDNKKAIEKIIGAKEPKEIYEILI--- +>tr|R4I1J2|R4I1J2_9GAMM PTS system, nitrogen regulatory IIA component OS=Serratia symbiotica str. 'Cinara cedri' GN=ptsN PE=4 SV=1 +-----IKCTKIIIHFINKKWALNIISTLASTtLQIQQLIIFNTVLTNEYIENTNIGNSITISCRALK--NNILKTVSIFIHLKQPITFNIIDNQRVDRLFTLLKRtnqCKTYLHILFLTIKLLANNTICCYLRTE-------------- +>tr|G5ICP5|G5ICP5_9CLOT Uncharacterized protein OS=Hungatella hathewayi WAL-18680 GN=HMPREF9473_01230 PE=4 SV=1 +-FQLMSERItILKCDCRSKEEVIELLGGRLYREGFVDEGFVESVFVRENLAPTSIGYTFAIPHA---YMGHIKKQGIGLMTLKHPIPWDNGEKVQIVLMLSIDVKSSDAFKIIFSqLADLTKDLPAVEQILK--------------- +>tr|A0A174J4C9|A0A174J4C9_9FIRM Probable licABCH operon regulator OS=[Eubacterium] contortum GN=licR PE=4 SV=1 +-KKFLNSSIsIMNCDLKSKEEVIKLLGGRMISEGYVDEGYIQSVFEREELSETSVGSLVAIPHA---FEGHIRKQGIGFMTLQKPIIWGS-EKVQIVFMLALDAKVENNFQRIFSdVLDLTRNIKDVEQVLR--------------- +>tr|A0A1E6VIK3|A0A1E6VIK3_LISMN Transcriptional antiterminator OS=Listeria monocytogenes GN=AJN46_07955 PE=4 SV=1 +---------FPKQNFKSKEEVITFLCEQLTAFDYCDSDYVSKVFEREQLSSTCYGNYYAIPHAI---QRSAKKNAVAVCALDKPIDWGGNRVKLVLLLTMKEERDNSFEELFGQLVTILNERSFVKKLAKQEDFQQFIELC---- +>tr|A0A1V8ZKD0|A0A1V8ZKD0_ENTCA Uncharacterized protein OS=Enterococcus casseliflavus GN=BH739_12400 PE=4 SV=1 +-----PNLFFMNEESISKELLLKKMTNKLAEEGYVSQDYFSTLWKREQETSTCVGNKTAIPHGAMKE---VNEPKIAVCTLKTKMQWSKdEEVQL---IFLLAAKMNTKvnIDKTKtfysDLIRITENEEIFEKLINSQDGVKAY------- +>tr|H1B496|H1B496_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium 6_1_45 GN=HMPREF0981_00029 PE=4 SV=1 +----------FQDSCENRRSLIHKYCTYLEDNGYVTEAFEASVYDRIQYSSTAIGRGVAVPHGT---KKAVKNSVILIIKLDHTITWDDQLVDL---VFFA-AIGEDISTeyskIFRRIVRIVSDDEQTHMLKSCNSLEEIRKY----- +>tr|A0A242CWE9|A0A242CWE9_9ENTE Uncharacterized protein OS=Enterococcus sp. 3H8_DIV0648 GN=A5875_003754 PE=4 SV=1 +----------YRDQLSTKEELITTYSALLEEKGFVDKDFGPSALTREQTIPTTLGRGIALPHGS---SDHVIHSCILIIKLEQTIEWSGHQVDL---VFLT-AVNQKDVEfhrsFFEQLFKIISNESLLNEIKSIVDVEALKKI----- +>tr|H3NPA2|H3NPA2_9FIRM Uncharacterized protein OS=Helcococcus kunzii ATCC 51366 GN=HMPREF9709_01163 PE=4 SV=1 +----TKEKILKLKEVENWEEAIKKASQILIDNRSINKQYVEDIIYNiNKIGPYvVLVDGVALPHAQ--NHNSVYKVDASLMIVEKPVEMKGKKV---DIFIVISVlDNISHLKMLATISDILDNKNNIEILRRG-DYREIRKLLL--- +>tr|A0A1S9C336|A0A1S9C336_9FIRM Uncharacterized protein OS=Epulopiscium sp. AS2M-Bin002 GN=ATN32_03240 PE=4 SV=1 +-------LILLNNNAKTKDEVIKTLVNKLYKNGKLSSeeGFLKAVFDREKLSATGLEGGLAIPHGKSNFVKeasfAVMSTKN-IVG-WESLDPDNEVKYIFLLAIPEAAAGDTHLELLSELMTRMSDEEYKEKLFASKDVKQFMTNLD--- +>tr|H3KHB0|H3KHB0_9BURK Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 (Fragment) OS=Sutterella parvirubra YIT 11816 GN=HMPREF94 +---VTLDAVRLDIAAASRKRLFEEASLLLESAyGVAHSEAFDALIARERLGSTCMGAGCGIPHGRIEGVTEP---CLVVLRTAEPVMLDAPDGRGVQLFFCLivpEGDSSEYLGILRECAAIMNDRPMRQALMSAPDATEVCRLIHE-- +>tr|A0A227KED5|A0A227KED5_9BURK PTS fructose transporter subunit IIA OS=Turicimonas muris GN=ADH67_11000 PE=4 SV=1 +---LKPDNILLGISASSKKRILELGAQTLSLLyHLDKKAIFDGLNARERLGSTYLGYGLAVPHCRMKDLDQP---RALFIRLNDRLENN-TESEPIEAFFFLlvpEEETDEHLQILAQISEIFSDKQEREKLKEASTVAEFAEVINQ-- +>tr|R3TT34|R3TT34_9ENTE Uncharacterized protein OS=Enterococcus phoeniculicola ATCC BAA-412 GN=UC3_01566 PE=4 SV=1 +----PVERIKVTTRKFTFQEAIQAVGEPLLKDKIIEQQFIDTIIQKY--DERYpyfvIAPQIAIPHAGYN--DGVNQLGFSLLKLKHPVRFSPR-LN-VSVLLMIAPIdNKKHQKAVQAFYDCVSDEANHQELLRQQTPEQLKKFF---- +>tr|A0A1L8WBQ1|A0A1L8WBQ1_9ENTE Uncharacterized protein OS=Enterococcus pallens GN=RV10_GL001463 PE=4 SV=1 +----PIDHIQVSNDPLSLEEAIVLCSQPLVKNRIVEASYAERIVANY--PKGEsyfsIAPKVALPHTTGM--NDVHSVGMSLLKLKEPIYFPNEKRW-VSLLMVVAPLnNDMHINAVTQFHKIVLDDKNVERLLKCREPEELRDII---- +>tr|F5YB74|F5YB74_TREAZ Fructose-specific phosphotransferase system, enzyme iiabc OS=Treponema azotonutricium (strain ATCC BAA-888 / DSM 13862 / ZAS-9) +-----KDAINTDLKSKTKQDAFEELLEAIQNVQPelNTEEALEALTARESQMSTGIMPHVAVPHALCPSARGAI---GAIGISRSGIDYNALDGSPVHLIFMLLanpESCSQSLRVLKHLAQLLDTPQFAADLIRKRTVEEIQGMLNL-- +>tr|A0A1G0Z9C0|A0A1G0Z9C0_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_50_93 GN=A2X45_09980 PE=4 SV=1 +-----AGRIKLHVEAEEKDEVFDELITRLVGTDHagRKDEFIKIIRERENIISTGFKDGIAIPHGRIDDLDGVV---GVLGISDKGIEYGSLDNNPARIIFMFLsskSRQDEHLAVLKRISRISDNADFRKDILLAKTPQSANKILKE-- +>tr|A0A1G3MHV8|A0A1G3MHV8_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWC1_61_12 GN=A2004_01695 PE=4 SV=1 +-----QDRICLDLVDTAKPELFAVLVSKLNQTLFrplDFMMACNALQVREARLSTAIGNGIAIPHAKITGINEVL---GVVGISRTGITYKASDDKPVQLIFLLLspaDTSDKHLHALKLLATALEKTTLRDDILAGSSDTALIwRCLQA-- +>tr|A0A1F9FVT7|A0A1F9FVT7_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFCSPHIGHO2_02_FULL_44_16 GN=A3C46_04810 PE=4 SV=1 +-----PESIVVPLKATTKLEVLEELVTELSKRTGiaNPKSLLHAIEEREACSSTFLPMGVAVPHARVPEVSDIT---MIAGIAPEGIMDAG---dpssltAHVFCLFFSSteeKEFGKHLKLLARIAAVFSDPDFVAKISHMTKPDQIFSAIQK-- +>tr|A0A1Y1S1X3|A0A1Y1S1X3_9SPIO Uncharacterized protein OS=Candidatus Marispirochaeta sp. JC444 GN=B4O97_04710 PE=4 SV=1 +-----PDSILL-LKEAGKTDTLGQLVSSVPEAASslSGKEILEKLLAREELMSTGIGLGLGIPHIRAAGINTPV---LRIGVQPKGIpDYESIDGLPVKILFMILlkeDQQREHVALLSEIVSLMKMEHLRNQLAAISSAQQGYDLLRD-- +>tr|F7K891|F7K891_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium 3_1_57FAA_CT1 GN=HMPREF0994_01864 PE=4 SV=1 +---LREENILLDVCCTDWKEVIQKATEPLLAAGSIDARYIDAMIRSYETNGAYFvyCPGVALAHAG--PEDGVRFFGLSLIRLKKPVSFGHRQHDPVTWCICLAIQeKDEQIQEVLRLMNLLGNPEKRPELDAIACSGELLQYIM--- +>tr|A0A1C5L5N9|A0A1C5L5N9_9CLOT Ascorbate-specific phosphotransferase enzyme IIA component OS=uncultured Clostridium sp. GN=ulaC PE=4 SV=1 +---LKKDHIVLDIPCTDWRDALSKAAIPLLEKGEIQPQYVDAIQHSVDVNGPYFvfCPGVALAHAA--PTDGVLEFCCSIYRPQEPVSFYHTQNDPVSLIIMIGITdVNTQVRYVSALMEVFRKKEFMERILHAQTPEKLITILL--- +>tr|A8RW19|A8RW19_CLOBW Uncharacterized protein OS=Clostridium bolteae (strain ATCC BAA-613 / WAL 16351) GN=CLOBOL_04455 PE=4 SV=1 +------SLVYHFPERTHKKEIISFLCARLAEAGYVTKDYEQTVLDREETTSTVLELGVAIPHGAAF---CVCRPVIAAAILEEPVDWGRDRR--VDRIFLLALNlderfkAkGQIIRFYSAIVTLLDDKEAYEEFHSLRGQEEIAGYLN--- +>tr|A0A1W6WC75|A0A1W6WC75_9FIRM Uncharacterized protein OS=Ruminococcaceae bacterium CPB6 GN=B6259_00845 PE=4 SV=1 +------RFVYFC-DHAEKTALLQTMCGDLEEKGYVLPGFNESVLQREKAASTQVGRRIAIPHGSTR---YVVRPIIAVAVLKNSIPWDRQDT--ADFVFLLAIQpdsllhMkPQMMKFYKVLSALIDDEKTLNEVKKMTDRQEFADYMN--- +>tr|U7DD75|U7DD75_9BACT Uncharacterized protein OS=Chitinivibrio alkaliphilus ACht1 GN=CALK_0603 PE=4 SV=1 +-------------ESEDKVSAITELAEAFCEiqKCDKAKRLIKDIIAREEAASTFVGQGVAIPQAVMNMKdEYAIMVG----RSAIGIDYGAVRNARAHIIALVISKknidDDDTFEVLSEISTFFRNET-VNKLIRSAEVERLSEVISE-- +>tr|D5SU40|D5SU40_PLAL2 Uncharacterized protein OS=Planctopirus limnophila (strain ATCC 43296 / DSM 3776 / IFAM 1008 / 290) GN=Plim_1190 PE=4 SV=1 +-------------TAKTRQGAIRALVQAANWddDGINPENVLEAIEEREAAAQTLVANDFALPHAFIDwDGDFRIVLG----RSKTRVDYGGPAGVNVQLIVLLVIGrrlQQTHVEVLAALAELLKSPDFRQNLIDAKDIKAIDLLLMT-- +>tr|A0A1Q6UHC2|A0A1Q6UHC2_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium CAG:312_58_20 GN=BHW65_09695 PE=4 SV=1 +-------------SAADFSEAVGQLLACIPDsilGGADRADVLANLIEREKSISTYLGDGICMPHTRVVgLKqKYVFAVG----RCSEaGINFEGLEDyRQTRILFLMLSDekVDNYLSVLSNLAKIFSSDDVCGRIKSSPDIAVFREAVMG-- +>tr|A0A0J7HU55|A0A0J7HU55_9BACT Diadenylate cyclase OS=Chitinispirillum alkaliphilum GN=CHISP_1305 PE=3 SV=1 +-------------NTNSKDQVFKHLIRLITDefPHTNYTEIMTLVQERESLISTRVSDSIALPHARIPgFPGTVAAVA----LSKKGILYDSLDDTKIKLCILIVGDGNNHLEALSWTAKRLSDPDRFNSILNASTPQKIVSILKG-- +>tr|A0A1V6E2H1|A0A1V6E2H1_9BACT Diadenylate cyclase OS=Verrucomicrobia bacterium ADurb.Bin122 GN=BWX86_01135 PE=3 SV=1 +-------------SSLDLEGALRELLAVSVSkfPDLKPEPLLRGILARESTMTTYLGLGVSLPHVRVKMKrRYILAIG----RSRLGLRHDGAREeDRIRIVVMLIAGetARDYLQVLASLARLLKEPDLVQSLSAAPDLASIYDRFVG-- +>tr|A0A1V6D3M7|A0A1V6D3M7_9BACT Diadenylate cyclase OS=Planctomycetes bacterium ADurb.Bin126 GN=manP_1 PE=3 SV=1 +-------------QASSKDEALKELALALCRhdPVLDVETVMRAINDREHAVSSRIAPRIALPHALVSgYNRQTLAVG----YSPAGISWDSPGGGGVNLVVMSVCGealADAHIRMLAELAGTLQDENTLERLTGAGTNWQVYEVLRG-- +>tr|A0A1Y1S425|A0A1Y1S425_9SPIO Diadenylate cyclase OS=Candidatus Marispirochaeta sp. JC444 GN=B4O97_01265 PE=3 SV=1 +-------------PAgqgVSKDEVIRRLCRAVAAdlGGMDAAQVESLVQKREASLSTRLSPLLAVPHAVIPhSKDNRMAVA----VIPDGLDWDSDRDNPVRLVMLLAGGREKHLKLLSEMAAVLQNEELLDRLISALNAAELISILRQ-- +>tr|S6CK95|S6CK95_LACCA PTS system galactitol-specific IIA component OS=Lactobacillus casei subsp. casei ATCC 393 GN=LBCZ_2702 PE=4 SV=1 +----DPSFVKHFLKAVTFPEVIDQLSANLLAKNLVTTAYLQAVKDREEKFPTGLPTepiGVAIPHTDAQ---FVKTNAVSVGILSTPIMMmvmGSENDKVEvSIIFLLSLgQSNKQLNILKRIMTVVQDQEMLNEFKTASDARV--------- +>tr|W7ZBP0|W7ZBP0_9BACI PTS system, galactitol-specific IIA component OS=Bacillus sp. JCM 19047 GN=JCM19047_483 PE=4 SV=1 +----DASFVYLNQSIHTKTELLTALGTQMETSRCATSGYTRALLQREQEHPTGIPFqptGVAIPHSDET---FIVKSKISLLTLRRPIYYeqmGTTSTFIPvSVIFLLGIkNDQAARKTVLTLLEKIQNRHFLSTIRSLSSPYE--------- +>tr|L5LB69|L5LB69_9MOLU PTS system, fructose subfamily, IIA component domain protein OS=Mycoplasma feriruminatoris GN=fruA PE=4 SV=1 +------NTSFFKQEFKTKTQIIDFLASKLKEEKIISKktVFLNAIKTRENQESTAIGNNVAIPHALN---SVVLKPTICFMSLKTPIKWNSNDNQLVDLIFMIATNdsdTNDHMDAIAGLSSKLLDDNVLEQLKQIDNFDQLIELFSD-- +>tr|A0A0W0RWS6|A0A0W0RWS6_9GAMM Nitrogen regulatory protein OS=Legionella birminghamensis GN=ptsN PE=4 SV=1 +------DCVNVDSSSKSKAAVFQKVSQLLSDNfsELNREELFSAYWKREALGSTAIGHGIAIPHVRVPGLNRV---RACFIRLLHPVDFCAEDRQLSDLIIALAVpenQSEYHLKLLREIIVQFSDQEFCRICRGLTCEKALFNLLIE-- +>tr|A0A1M7YBR3|A0A1M7YBR3_9FIRM Lichenan operon transcriptional antiterminator OS=Anaerocolumna xylanovorans DSM 12503 GN=SAMN02745217_02535 PE=4 SV=1 +---------------KNKNDAITKMTQNAISLGLAKESLTENVLQRESLSDTGFN-GVAVPHSL---REDVMKSFISFAICDTPMEWGAKQVYIIA-LIGVNQDSRKAFtEVFDFLVDVLSEMQNVKELASSADYDDFFQKLT--- +>tr|A0A109UHI4|A0A109UHI4_9FIRM Uncharacterized protein OS=Erysipelothrix sp. LV19 GN=AOC36_10080 PE=4 SV=1 +-------MFFVNEAPLTKEAVLNDLITQITQHAKLPKNFRALVWERERFSTTDVLPHIAIPHPNRLVSD---DSFVACMVLDKPINWGNHE---VSILFLpcLSKEDSEKYAFIyDWIIKLSNSKETILNIQNNKTYESLVNGVlK--- +>tr|B0N4Y4|B0N4Y4_9FIRM Putative licABCH operon regulator OS=Erysipelatoclostridium ramosum DSM 1402 GN=CLORAM_01695 PE=4 SV=1 +-------MVLTSINADTKEEAISFIINSTNYD----KNIIQEIIENDKVANHELDNMISILSLNGiSANN---QTEVIIGILSKPILWNEKR---VQLIIVplIGEPINSKILNLyHELAYMIKNPLYVKRIIRKKTYEEIIAIFE--- +>tr|G1VXC7|G1VXC7_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium 2_2_44A GN=HMPREF9022_04658 PE=4 SV=1 +-------LFYTDITGSDRTEVLCSMIQKLKKDIDLPDDFLELILERESFAATDLVNGVALPHPNRPVSA---QSFVSIGVLKHPVLWETKH---VQIVFLisIAPAQEQTISVFfEMLSDFVTQEKKIRQFLKKPSYDYMIQLIC--- +>tr|E5VHL5|E5VHL5_9FIRM HTH domain-containing protein OS=Lachnospiraceae bacterium 5_1_63FAA GN=HMPREF0996_00524 PE=4 SV=1 +-------LFYDNIKGETKEEILFEICKRIPEKYGIPSDFYEGLLRREEITGTDLAKHVALPHPYETTSD---ISFACISVLDHPIRWTRQD---VQVVILmaVAEDEQRDLTNFlQLISEFIANESAVLQLVEEPDFTTFVNLLS--- +>tr|A0A173V7E4|A0A173V7E4_9FIRM Probable licABCH operon regulator OS=Faecalibacterium prausnitzii GN=licR PE=4 SV=1 +-------LFFPHIQAGTREEALRQICHQMAQVYPMPeEEFCASVLAREQMGGTDFGNNVAIPHPEECFVK---ENVVCVAILDKPIRWSANT---VQLVILaaIYDSASAQAQKFyQLTSSLISDRVRVKRIIAKQEYEHFMKLLL--- +>tr|C5EFX5|C5EFX5_9FIRM HTH domain protein OS=Clostridiales bacterium 1_7_47FAA GN=CBFG_00820 PE=4 SV=1 +-------RFLSHVPVGSKEDVLKYICDVIEKQELVDNDFYDLVLERETYIQMDYGNMITLPHPNQIASE---ESFAYVAVLERPMVWNNLP---VQVILLtsIGRKGDKekERQRFyETTARFALSREAVSQLIQAPEYEVLVRQLK--- +>tr|A0A139TBW2|A0A139TBW2_9FIRM PRD domain protein OS=Candidatus Stoquefichus sp. KLE1796 GN=HMPREF3037_01820 PE=4 SV=1 +-------LFIVNLNCKDRKEIIKEMCHTISLYEDIPQTFEKSILEREAITSTEFGNHVALTHPLEPLSQ---RTFACVAVLKDAIIWKEKE---IKVVFLisIEQKKNKNIQDFyKMTSKLLMSEKYMNQFIKNPTFEDLMTILS--- +>tr|E7GFH4|E7GFH4_9FIRM Uncharacterized protein OS=Coprobacillus sp. 29_1 GN=HMPREF9488_03517 PE=4 SV=1 +-------LVLLQQTFQTKEDILNDMCHKIENIYSLPFSFQKFIEEREDLSSTEVGNLVAMPHPSSLCTE---QSIVMIMTLKKSILWKNNY---VKYIFLvsGNKNSKEECEFInENIIDLIMNNQWLQELDKISSYEELIHIL---- +>tr|E7MQ19|E7MQ19_9FIRM PRD domain protein OS=Solobacterium moorei F0204 GN=HMPREF9430_01544 PE=4 SV=1 +-------CFIPNLKAKTKEEALRVMSKRLMQKYEFKEDLYDSVIRREQMASTDFCYKTAMPHTDKLISE---KSHVCIGILKEPIIWDENE---IQLIFLvsVGKDRK-ESQEFySLISKFVLNEKMIDQLINTSSYEIFIKTIS--- +>tr|B0N173|B0N173_9FIRM Putative licABCH operon regulator OS=Erysipelatoclostridium ramosum DSM 1402 GN=CLORAM_00434 PE=4 SV=1 +-------LFFTYESFSSKEEAIHEIINECKKSYDLPADFEQYVLQREALATTEFNDLIAFPHSNKPVSN---ATFVAVTILKKPLLWKKHK---IRIILLsaIENKAIKELDDFyKIISNIISDSTIQWNLINNPNYQYFKEIIE--- +>tr|A0A1C6ELB0|A0A1C6ELB0_9FIRM Probable licABCH operon regulator OS=uncultured Eubacterium sp. GN=licR_8 PE=4 SV=1 +-------MVFWS-SSDDKNEILKHMCENAVQNYNIPDDFFHYVMKREDIGRTSFGNLITIAHPIHPIGQ---ESFVGLTILDHPIDWDGEP---AQLIFLlsMKESGENKMKDFyKAMTKLVNNTHYIELLTKTKNYDEVINILK--- +>tr|A0A1C5MHM9|A0A1C5MHM9_9ACTN Probable licABCH operon regulator OS=uncultured Collinsella sp. GN=licR PE=4 SV=1 +-------WFDPHLDAETPHEAICGLAELMVERAGAPAELVELALERESAASTAFGSGLALPHPIRSLPG---PTKVCAGIPNRPIRWGDKD---VELVLLvaIGDDGR-nALDWFfSRMAELLSHEERVKRIVDDRSFEVMMQEIA--- +>tr|A0A1E8R8Y9|A0A1E8R8Y9_9FIRM Uncharacterized protein OS=Anaerococcus sp. HMSC065G05 GN=HMPREF2852_02660 PE=4 SV=1 +-------LFFNIKENCNHKDILDFLSKKVNKRTGINsKIYYKELIDREELASTCFENKVAIPHPLNSVCN---ENFISVLINKNSIKWKNQK---VNIVILinINELIDNeIVENFyKILSEYLTNNDKILKSMQAENLEEFLKEFL--- +>tr|A0A242K5Y9|A0A242K5Y9_9ENTE Uncharacterized protein OS=Enterococcus sp. 9E7_DIV0242 GN=A5888_002665 PE=4 SV=1 +-------LFFENIDLSTKEEVLRFLVAHIADS-DTQEHYFHSILQREQLGATEYGNQIALPHPLEPVGD---TSIVAALSLKKPILWQKKM---VRYVFLfsFSKQSEKDVLIVtDFLTELLFDINSLQQLKKNFSFPTFQTLWN--- +>tr|D1AJW2|D1AJW2_SEBTE Transcriptional antiterminator, BglG OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_0134 PE=4 SV=1 +-----ENNIEILDRLESWSDAIKVSGELLIKQNYVTKDYIQEMKELVEKFGSYivVADGIAIPHGSIG--KNVIKDGAALLVLKEAVKFDDGE--MVNIFIPFATRGkKFHSKLLNEIFDIIKRKNLKDKILSLKTKQEIIKYL---- +>tr|A0A200IFR9|A0A200IFR9_9ENTE Uncharacterized protein OS=Enterococcus sp. 6D12_DIV0197 GN=A5867_001530 PE=4 SV=1 +-------DLFVAKSSmKNKNQVLSLLCRRLEEKGYVDPAFERQVYRREEAAATAFQ-NIAIPHSV---QMDAIKTSIAVTISKTGIRWGKHTVYLVLL-IAINKADKQTfRELYESLIALFNDQPTIQEVRNCQSFEDFKKLIYS-- +>tr|A0A0E9FNJ2|A0A0E9FNJ2_CHLTH Probable licABCH operon regulator OS=Chlamydia trachomatis GN=licR_1 PE=4 SV=1 +----------IEHGHTDRLTVLQEMTKRLQLCGAVTPYFLESVLKRETMGSTEVGNGIILTHGFYEA---VKRTQIAFYKLDNPIFWNTQKVNFIV-LLAVAKVDAKNVMQMSWLYKTLNSESIIEQVHKCSCEKELYELLIN-- +>tr|L1Q846|L1Q846_ANAHA PRD domain protein OS=Anaerostipes hadrus DSM 3319 GN=HMPREF0369_00641 PE=4 SV=1 +----------VFHEQIDKIQILQEMSNYLRMCGAVTPRFFEGVLKRENMGSTEVGDGIILTHGFHED---VKRTQIAFCKLDHPIVWKTQEVDFIV-MLAVAKTDAKNVMQMNWLYKMLSNMEIVNKIRECKKDREIYETLIE-- +>tr|A0A0A1MQS9|A0A0A1MQS9_9BACI Putative licABCH operon regulator OS=Oceanobacillus oncorhynchi GN=licR_6 PE=4 SV=1 +---TAPSCIHLREKVSDWREVLSILNQSLVKQDVVEHTYETEVAQiiNEQEHHFIVAPGVAFPHLSS---TAIKKTGFAFMTLEEPISFGGTEEKVW-WIILLAAKdKIQHVTAVEMMLEVVNSKELLDKLRHERNIDVVWKWMLE-- +>tr|A0A162Q224|A0A162Q224_9BACL Uncharacterized protein OS=Paenibacillus glacialis GN=PGLA_16875 PE=4 SV=1 +---LPCTSIRLQLDSMDWESAIQMGCQLLSERSLSGLNYEERLVEmiDSNIHSFIIHDGVAFPHANMP--GDIRQTGFSLVTFREPISFGPLAHPVW-LIITLAAVdKEQHVGALSTLLDALNDEMFMTDLQQSSNSYDIWRSFRE-- +>tr|A0A0R1KDY7|A0A0R1KDY7_9LACO Uncharacterized protein OS=Lactobacillus paralimentarius DSM 19674 GN=FC78_GL000532 PE=4 SV=1 +-----PELVFVNSNLQTRKQVLDFLCDKLEEQAVVRSDFREKMFEREKMYSTAIGGEIAIPHPIKFA---ANKSNVAFMQLKKPIVWDD-NDNKIQliFLLAINEEEYPKIQTLFSFLVDLqSDTRFYNAISKCKDSNEAMKVIN--- +>tr|E2SHC0|E2SHC0_9FIRM Putative licABCH operon regulator OS=Erysipelotrichaceae bacterium 3_1_53 GN=HMPREF0983_00369 PE=4 SV=1 +-----EQL-FINTTANSKEEIIHTLCMMLHQEQCIKDDFEASVLEREQRISTAMDGVVAIPHPLVMC---SLKSKIAVGVLQKPIAWS--EKDSAQiiLLLGLADDAKKDIEKLYDTFVAMtHNAPLQELLFHAGSLSEFLNILK--- +>tr|A0A242NLG6|A0A242NLG6_9GAMM Uncharacterized protein OS=Gilliamella apicola GN=B6D08_00715 PE=4 SV=1 +-----PENFyYFDTDKLSKKDLLVKMAVDLEKQNIVSADFVSSVLERESLQTTLINDVIAIPHSMTMI---ANRSRVSVAIFPNGIQWE--KDKKCNfiFLLAISKTDNEITDNLYDLILNLiDDKAMTKQLLKAYTFHEFKNLLS--- +>tr|A6DML2|A6DML2_9BACT Probable fructose specific permease-possibly phosphotransferase system component OS=Lentisphaera araneosa HTCC2155 GN=LNTAR_160 +---LDEEHIITGLNAKNKWEALREMSYFLVKTNDIEidpEELLKRMEEREKEFSTGFGQSIAIPHCTVTDeesHDGKIR-G-MLAVCTPGVEFESMDDEPVEIIVMLATpesQREAHLEILSVLGRMLSDATIREQILKANCAASIYEIIHS-- +>tr|F4LRK6|F4LRK6_TEPAE PTS modulated transcriptional regulator, MtlR family OS=Tepidanaerobacter acetatoxydans (strain DSM 21804 / JCM 16047 / Re1) GN +-----DEKLYFKNkGIKNKVNAIKFLGNHLEKMNICEKGFTESVLRREAISSTCFLGTFAVPHA-IELNA--KFTQFCVLIEEDGIKWDDN---NINCVFMIAVSKDDRkafMEIYSGIVQILCDKESIDKLIKAPDFSSFINHF---- +>tr|H1BBX9|H1BBX9_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium 6_1_45 GN=HMPREF0981_02712 PE=4 SV=1 +-----SENLFFISeKINTKDLAIQFLAEQLKKDGSVNDTFIDNVLQRESLSPTCFMNSFAIPHS-FQEDS--IKNRIAILINKNGIQWNNQ---TIYAVFLIATSKNSIkrfnKLLFERIGYLF-SENNKQKYLAIDSYDSFIKYL---- +>tr|A0A0U9HG12|A0A0U9HG12_9THEO Lichenan operon transcriptional antiterminator OS=Tepidanaerobacter syntrophicus GN=TSYNT_8139 PE=4 SV=1 +-----SSDLFLYTtKIKNREEAFKVMTKIMKEKGIIDERFITSLYEREALSSTGFMNSFALPHS-LEYNA--VCSKIFALVNPESIKWGDA---QVKIVFLIAISRKDRekvKPLFDFLTDIMIDEQKIYNLSKAMNFENFMQIL---- +>tr|A0A133L1Z4|A0A133L1Z4_BACCO Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Bacillus coagulans GN=HMPREF3213_00215 PE=4 SV=1 +------AFIVLDADYKTQAEFFCASSAILKQREYVKPSFCKAVMEREALYPTGLAneyIQFAIPHTDAFHVEK---PFVFVTRLKNNIPFMHmgtTDIPVQaKviFMLGIK-NPEKQVGLLSDIMKCFNDGDFVRTILSIQDTHAMADYLK--- +>tr|W5SP83|W5SP83_BORAN Na(+)/H(+) antiporter OS=Borrelia anserina BA2 GN=BAN_0070400 PE=4 SV=1 +----KKENIILDLKATNKIEVLRELLGVIKVE----iDkeTILQDLMEREKLITTALKEGFAIPHLKTNLIK---KMHIAIGISHNGIDFNAIDKNLSHIFILILYPakeYINYPRILASIVGKVGS--NKKAMLKATTNKEIYNIIV--- +>tr|A0A1G1Q8F9|A0A1G1Q8F9_9BACT Uncharacterized protein OS=Omnitrophica WOR_2 bacterium RIFOXYA2_FULL_38_17 GN=A2243_07050 PE=4 SV=1 +----SSKALNVDLQGRSKEEILAELVELLIESKQLDasQkeEVVKDLLKRELMMSTGMQNGIALPHAKTIAVD---HVVAAVGISKEGVDFASLDKIPSKIFVLTLASkehPHAYLQSMSEISRFLSKEENRAKMIACTTRIQLFDVLS--- +>tr|A0A0F7E441|A0A0F7E441_MYXFU Uncharacterized protein OS=Myxococcus fulvus 124B02 GN=MFUL124B02_01000 PE=4 SV=1 +------EAICPSLRARERVGVLHELAGMMADEAGVpARELAVHLLAREQLGSTAMEGGVAVPHCRHARAGRIV-T--CLGIHRGGLAFGEPEDGLVRIYVGLVSPPdtgGLHLNVLSRIATLLHDVRVRDALMAAASPAVIRALLVR-- +>tr|A0A1F9UJQ0|A0A1F9UJQ0_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_59_12 GN=A2992_02965 PE=4 SV=1 +------QTVAFFPAGPSKRQVLGSLIGLFDLADPGa---ALKAILAREEAGSTVIAPGLALPHARITGIPRLR-A--ALGLCPGGIQYSHAVEEPVKLVLLFLGPAenmREHLAFLAGASALFQNSELVKRLLTLTSPKPVLRGLQE-- +>tr|A0A140DY33|A0A140DY33_9FIRM Uncharacterized protein OS=Faecalibaculum rodentium GN=AALO17_24260 PE=4 SV=1 +------ENLFVRFdDPVTKDQVLDELCSRLTTAGISGPDLRESVRKREEISHTNLNDIFAIPHP---MTPEASRTRAAVAVLNHPVVWNDKG-SAVQIVFLLAFCKGEqqSIERLyDYLLEIVQSVPLQQSILKAGTFEEFQTLCL--- +>tr|R2S7W1|R2S7W1_9ENTE Uncharacterized protein OS=Enterococcus asini ATCC 700915 GN=UAS_00034 PE=4 SV=1 +------ASMFVINnQKTTRDTLINSIGNILEEQEVVNIGFTKKVLEREHIAPTNITDLIAIPHA---IDANIKQTKIFVYISQSPIIWRDD--KTVKIIFLLAVAEEDkeNLHTFfEYLSDLVENKKLQQKIGNSQNFEMFLSSLF--- +>tr|A0A1T4RE50|A0A1T4RE50_9ENTE Transcriptional antiterminator, BglG family OS=Pilibacter termitis GN=SAMN02745116_02562 PE=4 SV=1 +------EKFFFPKmNFKNKEEALSFLCNHFEN----GEKFLTSILKRERIQDTYIQNGIAVPHP---IDFYFKETKIAILSLEKAIPWNQSG-KKAELIFLIAPAKCDlkELDDFfEQLILLLNNRPLRRKIVQTNNFQELLTLFQ--- +>tr|A0A062XZH2|A0A062XZH2_9BACT Uncharacterized protein OS=Thermoanaerobaculum aquaticum GN=EG19_04805 PE=4 SV=1 +---FGPEHVLDQLTASTREEVIAEIVKFVAEKRMVTdPRWLeTALIQRERMVPTAMPNGVAFLHARHRAADKFPRQFLALARSKEGVSFGSPDERPTHLFFLLAFRRDqAHLRWLARLSWICRRRTTVSSLLQATSAEEISRQLAL-- +>tr|A0A1W9S0Y1|A0A1W9S0Y1_9BACT Uncharacterized protein OS=Candidatus Coatesbacteria bacterium 4484_99 GN=B6D57_02865 PE=4 SV=1 +---ISSKTIKIGLTGKTKDEILKEMVEVLSNSGNIKdPNRIyEAVVERERLCSTGFEHGVAIPHPRQGQPDIVENLTIAFGSSKNGVDFEALDEEPVYIFFMLAAPNDqEHLRALARLSRMLKKEEFREELNKAKTPDDVLKLISK-- +>tr|A0A1M6TWY0|A0A1M6TWY0_SELRU Transcriptional antiterminator OS=Selenomonas ruminantium GN=SAMN05216582_10985 PE=4 SV=1 +--------ENVPDKKALFRSLIQNAPQELQQQAPA---IITALCQREKLGDTCIAPGIALAHAQiPEIS--APYL--AATIIQEPVPWDQEGN-PVHIVImiLLPMiPAASSIHQLHDLMHKLADEELTDKLAAHPTPENLRQYLF--- +>tr|A0A0H0TJ97|A0A0H0TJ97_BRAHO PTS sugar transporter subunit IIA OS=Brachyspira hyodysenteriae GN=SZ53_00160 PE=4 SV=1 +-----KERIFLENTSSSKEELFDFLSEKISELDPSydAENIKEGLYDREKDGNTVIADMVAMPHARMESIK---EIKVTIVSLLKPIEYSPDESiDLAYSIVAPIDANDEFIDVLTLIAMVVQDEELQNIIRNSKV------------ +>tr|B9Y3S9|B9Y3S9_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_00459 PE= +-----QEYIHLHCPAVTKAEVLQTASRWAAEAEIIadAALFLKGLWDREAEFSTGVGDGIAIPHCRLESIR---QPSVFFAHLENPVRWSPEEEvDLILVLAVPQSnAENTHIRLLSQLARKLVDEVFVSQLRELDQ------------ +>tr|A0A0C7L7M4|A0A0C7L7M4_KLEVA LicR protein OS=Klebsiella variicola GN=licR PE=4 SV=1 +----------IFEqSEHNKDSLIEFLARRLESTGKVDARYLPSVVEREAHASTLLADKIAIPHPM---GLVASTTQVTVAVFPQGIEWDAG--KVVKLVFMLAISEDAfvDSMIIYDYLTNILDDDIIDKLSSFDTFADFM------- +>tr|A0A0R1UZE3|A0A0R1UZE3_9LACO Uncharacterized protein OS=Lactobacillus satsumensis DSM 16230 = JCM 12392 GN=FD50_GL000512 PE=4 SV=1 +-----SAELVEFnefKEPFSKLNFLKYATQILEKMHIADRQFLNELLERENMSTTAFPTGVVIPHSM---HMNALKTKILIVKFEKPVIWGGQR---IKFAFVVAQNTKDAqifNDFFQQLVEVLSDIYNVDMLYNSESSDELLNKI---- +>tr|X5NX75|X5NX75_ENTFL Transcription antiterminator, BglG family protein OS=Enterococcus faecalis CBRD01 GN=P746_01266 PE=4 SV=1 +-----AKELYFSqidPADLTPEMLLDQMIQRMSIQKYCSSDFKKKCEKTRAAFSNKLSIRYRCPPCY--------------------------------------------------------------------------------- +>tr|A0A160NAA5|A0A160NAA5_ENTHR PTS fructose transporter subunit IIA OS=Enterococcus hirae GN=A6P53_11230 PE=4 SV=1 +-----IEDLYFNqfdPTDQTPKMIREKLFDRLLVTGYVEEEFSQRMEKREAMSSTSFPSGIAVPHSL---EQQAKKSALSIMTLQETLKWDEYP---VQIVALVAISQDEAkefNDFFEMFIEIVSDPINVRLLAGAENFTEFILKM---- +>tr|R3WMX4|R3WMX4_9ENTE Uncharacterized protein OS=Enterococcus phoeniculicola ATCC BAA-412 GN=UC3_00114 PE=4 SV=1 +-----RDNHFIVhYTGHTYEEALRAIADKLRKSQSVSDNYFDQLIERENASYTSFPSGIAIPHTL---AMDAKKTDVVILIPKESIPWGETN---VRLIVGLSISKKDRkifNKIFQRFVEVVSVKENVLMLSKQENPKQFLSRL---- +>tr|A0A173M3P3|A0A173M3P3_9LACT Putative licABCH operon regulator OS=Lactococcus garvieae GN=licR PE=4 SV=1 +-----QENAFIHlKGEISKAAAFEKIGQWFFKNGFAEKEFAEKLFEREGLSSTSFSSGIALPHSI---RYEGRKTGILIFKPEKPLHWDNQI---VQLILSFTISPDDSkdfNKIFPHLIEILTEEYHVEYLRRSENRKEFLERM---- +>tr|C7HSJ3|C7HSJ3_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Anaerococcus vaginalis ATCC 51170 GN=ptsN PE=4 SV=1 +----TDKNTEFDIVVKDWEQAILETGKLLEESGYANENYKYNIINDVKNYGSYImiSPNVVIPHTRPE--NGALKIGCTIITIKNDIYFDDNNKDAIKVLIGFTAIDnKNHLEMLKNIINII-EKGLVDKLNYFLNLSKKDKLIY--- +>tr|R9LKM6|R9LKM6_9FIRM Uncharacterized protein OS=Firmicutes bacterium M10-2 GN=C815_02282 PE=4 SV=1 +---------HTTIKAQTVEEAIEKMCKPLIADHYVPEEYVQAVLERETFAPTSFYMGYALPHALNQE---AYKSAISVAWLEQPLRWGNYD---VFFILLLSIREEDrdLLRIfFDWWTQIVSDRMRYLKLMEKRTYPSFMRAL---- +>tr|B6FYB2|B6FYB2_9FIRM PRD domain protein OS=[Clostridium] hiranonis DSM 13275 GN=CLOHIR_00864 PE=4 SV=1 +---------HVHETYESSDEIINKLCNELVEKDLADERYKEDVFRRESMSATSFSYGFAVPHSMEVS---TKESCLSVMVLDKPVKWGDFD---VRLIILLGIRDTDnsLLKIfFEWLSNTVTDSKKLARLLAVNNYEDFMKEV---- +>tr|A0A142KDF0|A0A142KDF0_9ACTN Uncharacterized protein OS=Propionibacterium acidipropionici GN=AXH35_00210 PE=4 SV=1 +-----------NGAVTTREDAIRTLCNRFIAAHVAEADIEERVWERERISATSFPSGFAIPHPItMSG----NKSAIGVLRCGSSIDWGGQPVQLVAMFSVRPAERDLFGEIFEHFVRMLLSRPNVEALLsSADNFDAFM------- +>tr|W7CYC3|W7CYC3_9LIST Transcription antiterminator OS=Brochothrix campestris FSL F6-1037 GN=BCAMP_09175 PE=4 SV=1 +-----------DVIKESKEDYIAFLGHELVDAKIITSSYYESVLEREKMSSTSFN-TVAMPHSLyRTA----KQSIFAVLYNKAPIIWDVHQVDLVLFMAISQDDSDRFNDFLQLIIEIASDPIAVRAIVEQTHYEGFM------- +>tr|A0A0M4GSV2|A0A0M4GSV2_9ACTO Uncharacterized protein OS=Actinomyces sp. oral taxon 414 GN=AM609_13030 PE=4 SV=1 +-----------VEEELTQDEALERAFGLLRAAGAVGHSFLDDVRDRERRSPTAFGGRFAIPHSLyMDA----ERTALCVLVLAHPVPWGASAVDLVITLAVGPQERAVFRDVLDELVRVLSDPVGVDALVsAGIYYAGFM------- +>tr|A0A1T5K7I4|A0A1T5K7I4_9MICO Transcriptional antiterminator, BglG family OS=Okibacterium fritillariae GN=SAMN06309945_1969 PE=4 SV=1 +-----------NLTVADSDTMIRTLGERMVEASVVDQGYVEGALQRERMSSTAFTEALAVPHAMtMTA----TRTAIAISVNETPLSWGEYRVNVVAFIAFSAVDRGSFQSVFDQFVEVFSNRADVQRIVrNAVDFPSFI------- +>tr|A0A221RZZ2|A0A221RZZ2_LACCU Uncharacterized protein OS=Lactobacillus curvatus GN=CGZ47_07610 PE=4 SV=1 +----QPELTIVTQERLTDQGAIELIGQRLIDQGYAKSTVVQAALAREALASTALG-RVVLPHADSQ---LITKPAIGLLIAPQSINWQHN--DKVQLVFFMALNETVHGQmrAiYHDLDQLIETPRLLKQVAQASDGTAALAILAQ-- +>tr|A0A1I3FJ93|A0A1I3FJ93_SELRU Transcriptional antiterminator OS=Selenomonas ruminantium GN=SAMN04487861_11548 PE=4 SV=1 +-----EPCIRLDGEAGDWETAVTQAGNLLLAEGAVTEHYVRQMVRVVRNIGPYivVCDGVAMPHAHIE--DGARKVAVSFLRLKQPVFFSD-DKRPVDMLFAFSTTSeKAHLPLLSDLWRVFNSEHMLQALRTCPDAVTMRQQLQ--- +>tr|K1XDG6|K1XDG6_9ZZZZ Uncharacterized protein OS=groundwater metagenome GN=ACD_79C00364G0002 PE=4 SV=1 +----KSGGIYYRISGNDKKSVLMSVVENLKLPESVNREYlLEVLLAREELSSTGIGEGIAIPHVRNPIIFNIPKSLISLCFLEKPIDFGSIDDKPvHALFLMMCATPRIHLGLLSRLSYSLKDEKLKQAIINQASREEILTEFR--- +>tr|E8QXY6|E8QXY6_ISOPI PTS IIA-like nitrogen-regulatory protein PtsN OS=Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B) GN=Isop_0370 PE=4 SV= +----ECGGVYWDVPGSTPSEVLEAIVDRVPMRPDVPRDDlLALLRSREGVGSTSLGSGFAVPHPRYPLVHATVPPTLAVCHLAAPIAWDPNNPaDMvQTVFTLIAPTPRIHLRLLAKLMYALSDSAFRNVIARKASAEETITAAT--- +>tr|A0A1G0XXQ3|A0A1G0XXQ3_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_45_14 GN=A2020_15470 PE=4 SV=1 +----RKGGIHYKVAGSTVEEILKNAVALINAPPGLDKETiVWHLLKREAMMTTALGSGIAIPHPRTPLISDISCESVSMCFLNGPVDFKALDNMPvSVLFIVLSANQPRHLQILSQISHLCRKDGFMELIKRQALREEIFDYAG--- +>tr|A0A1J5DFF8|A0A1J5DFF8_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium CG2_30_63_29 GN=AUK47_25160 PE=4 SV=1 +----RAGKVHRDVPSNGRESTIRAIVERTVLPASLAPAFvVAVMVARERTLWTAIGNGIAIPQVRQPIIAAGLPVTVSVSYLEQPLLFGAPDGKPiQVIFQIISPTIGEHLRVLAHLSRALLDPGFCAVIERRGSNEDLAMAAH--- +>tr|A0A1J4SVH6|A0A1J4SVH6_9BACT Uncharacterized protein OS=Elusimicrobia bacterium CG1_02_56_21 GN=AUJ51_03380 PE=4 SV=1 +----LEGNIHYGVPGGDKKAVMTAVADLLPLAKPGDKALaAQALWNREVKGSTVI-DGIAIPHTRSPLIFGSARPIATICFLKDKVFFDPGDKAPvRIVCTLVTPSIRAHLAILARVASTLHDKEFRALLDRAAPEEELLARLK--- +>tr|A0A1V5HIF2|A0A1V5HIF2_9BACT Nitrogen regulatory protein OS=Lentisphaerae bacterium ADurb.BinA184 GN=ptsN PE=4 SV=1 +----RADRFIMDMRARSASGALDELCALiSAKNLCLDTKDlRQRIDAREELLSTGVGHGIAIPHPRDPVPTLPEPVIIIVGISQKGIAFNSADGKPaHLFFLLCDQNIEMHLHMMGRLAKLLSNSETVDLLRGAKTPEEFLRVVM--- +>tr|A0A239A9Y4|A0A239A9Y4_9DELT PTS IIA-like nitrogen-regulatory protein PtsN OS=Desulfovibrio mexicanus GN=SAMN04488503_1929 PE=4 SV=1 +----RAGGVMRGICANTLPELLCPVVGHmIPDAPEHQRELvLAMLLAREATGITAVGGGVLAPHVRAPLILGET-PRIVLVYPARPLPLSavpTPDNAPiEAVFVLASPTVRAHLTLLALLAAALRDADFRQAVLSRASEAALLTAAA--- +>tr|M7NM22|M7NM22_9MICC PTS system, fructose-specific enzyme II, BC component OS=Paeniglutamicibacter gangotriensis Lz1y GN=fruA_2 PE=4 SV=1 +------QMVALQMVTPTRDSTVAALAGLLQDAGRLSdlPGFLADVHRHEHQLATGLPGGIGLAHARSD---FVSAPSIAVGvmAYGQSLDFGATDGP-AHVVLLLATPassYSEHLMMLAALARSLAKDSFRESLRRANDAGVIAGLVG--- +>tr|A0A143WX38|A0A143WX38_9FIRM Putative licABCH operon regulator OS=Clostridiales bacterium CHKCI006 GN=licR PE=4 SV=1 +------EFFFEHLTGKTREEVIQEMCTKISSVHPLPETFYDLVMEREAVSPTEVGNGIAIPHPLHLVMD---ETFVAVGVLDKPIRWQKQQ---VKLVFMlcIQKDSDEALSVFnEVLSSLVLNRECVQKLEKEPCFHTLESYIHA-- +>tr|I3BR37|I3BR37_9GAMM Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Thiothrix nivea DSM 5205 GN=Thini_1212 PE=4 SV=1 +---LSPERVSCETEVSSKKRAFEQLAALLVTGyaGLEAETIFHALINREKLGSTAIGNGVAIPHACLPI-P---QPLGALLVLEDGIKMDAPDKKPVQLFLAILApanEAPNYSELITRLTGTLLQKSLIEQMCRYNDRQGMLDQFR--- +>tr|A0A1V3TS95|A0A1V3TS95_9PAST PTS sugar transporter subunit IIA OS=Pasteurellaceae bacterium 15-036681 GN=BMT54_05725 PE=4 SV=1 +---LPFENIHCDVDASSKKRVLELVGYYIAEyfnkneasqlnEnkGVCPIDCFSLLFKREKLGSTSINNGVALPHAKLAECECStiEKPVAVFLRLEKGVDYEAQDNRDVDLIYAVLFpeqSCERYKGALQKIAQQLNDKTLLKQLRAAEDSQAIWSILQ--- +>tr|G0GFU3|G0GFU3_SPITZ Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Spirochaeta thermophila (strain ATCC 700085 / DSM 6578 / Z-1203) GN=S +---LHPEYIKLKARISSFEEGVRLLLGLIRGLVdQDEKTLFSRVQEREAQAPTVLDHGLCVPHLRLDDFDDHV---IAVAVPERPFTYGGKEVDILILIISSKAQPSTYLNTLKGLATLFKDPDTREALLSAKHPEQFIRIIA--- +>tr|E0RRW0|E0RRW0_SPITD Uncharacterized protein OS=Spirochaeta thermophila (strain ATCC 49972 / DSM 6192 / RI 19.B1) GN=STHERM_c07970 PE=4 SV=1 +---LHPEYIKLKARISSFEEGVKLLLGLIRGLVnQDEEALFSRVQEREAQAPTVLDHGLCVPHLRLDDFDDHV---IAIAVPERPFTYAGKEVRMLVLIISSKAQPSTYLNTLKGFGLLFKDPAIRESLLSAKTPEQFLRIVA--- +>tr|A0A098QSN8|A0A098QSN8_9SPIO Uncharacterized protein OS=Spirochaeta lutea GN=DC28_15415 PE=4 SV=1 +---LDDRLVLWKAKTTTLDSMVEHMLDKLYQyeDVsASRKQVTELLNARKALGGMVFETGLAIPHARIPGLRDLW---ILPGVPAEPFWENEVEVRLVVLFLVPAEVSEYYLPVLSYLTRLSRDNDVFSQWIGQPTRDAFIDYT---- +>tr|A0A1G3NWP7|A0A1G3NWP7_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWF1_31_7 GN=A2015_06855 PE=4 SV=1 +---LNEDYIVINGNLKNKEEIISFLIRQFERnyDFkIDSPKVINTIEERESLGGTVLPTGVWIPHGRLENFNDII---VSIYIPEEEFIQEGISVKMVVLFLIGKTTSNLYLKILSAFAQISSNESLFETILKSKDPRHFISNIE--- +>tr|A0A1G3LE82|A0A1G3LE82_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWB1_59_5 GN=A2Y38_08375 PE=4 SV=1 +---IDPHLVLLDADVDSIDSAIEVGLKAIVElyPQeVMYDEVIQRLTERRLLGGTCFPTGISIPHARLPVFNDFI---IAAIVPHKPIISGEKcidtscadipPVRIVWLILISQTSSSIYLNTLAKLLEASKSESMMDALTSAESPSQFISIIE--- +>tr|A0A1V6K9K9|A0A1V6K9K9_9BACT PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC OS=Candidatus Cloacimonetes bacterium ADurb.Bin003 GN= +---LEAHNILFENRVLTKEQVYKKLVDRLCSqyKLpVSGSKLLELILHREEEVSSAYPTGIAIPHIRMDGFNDTL---IAMAFLENPLDYNGIKVNWVVLILTDKTSSKTYLNIVAALLKLSKDKVAMKALASAGDGQSVIHYLK--- +>tr|A0A1W9VQA3|A0A1W9VQA3_9SPIO Uncharacterized protein OS=Spirochaetaceae bacterium 4572_7 GN=B6229_05490 PE=4 SV=1 +---IDSDFIITGKEFGSVVDAVNSLIELFDKkkILtASTDIVKTKTLDREKLGGTLLPPGIAMPHARVEGVDDLI---IGVWVPPKPLETDDGIVKILFFFLTSIAGSSLYLPMLSSIAKSCMDDKFFNKLISSNKDEv--HKLL---- +>tr|A0A1V6F6W9|A0A1V6F6W9_9BACT PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC OS=Candidatus Cloacimonetes bacterium ADurb.Bin088 GN= +---LDARAIAFEQRVLPREQVYQEIIQRICAqrshNTpKCGQPMLDAILQREREAPMAYPSGIAIPHIRVEGLADTL---IGMTFLQNPLDYDGIKVNWVVLIFTDKSSSKIYLNIVAALLKLSRDEEAMKSLHGLHDGHDVIHWLK--- +>tr|A0A1V5V5J8|A0A1V5V5J8_9BACT CBS domain protein OS=Lentisphaerae bacterium ADurb.Bin242 GN=BWY31_01296 PE=4 SV=1 +---LNQNLIFFNVEGNDRETIYNHLISLMAKtvSLpCPPARVVSDIIAREDLINIVYEKGFAYPHIRYPQLMDLN---VVIGVLKKPVLLKQNdreETRIIVCSLVSPETSVIYLKVLAAFSRYFLlAPDAIAKLVNTGSPKAMIDFLQ--- +>tr|A0A1V5T9F4|A0A1V5T9F4_9SPIR PTS system fructose-specific EIIABC component OS=Spirochaetes bacterium ADurb.Bin269 GN=fruA_2 PE=4 SV=1 +--------------HSTRHDALVALADVLGTAPQIKnrQELSLEILKREELMSTAIGRGIAIPHVRLSsVTDLVVAVGLCKNDII---DFQTIDDVPVRLLFMIAAAYNQHayyLQTLSFFSTRLKNPALREGLLAARNPMEAYNLLIAK- +>tr|E2SP70|E2SP70_9FIRM PRD domain protein OS=Erysipelotrichaceae bacterium 3_1_53 GN=HMPREF0983_02962 PE=4 SV=1 +---LEQSSIVLDAsYGVNWMDAIWECAQPLLEQRCIEKNYITRMIELIHGYGPyiVISQRIAIAHAQPE--DGVLHLGISLHIYPKGLTIGNT--SIQFLFVLATPNQSDHLHILQDIMTLNEHEEYMNQIVQAENAKQVMYYLQD-- +>tr|H1BNH9|H1BNH9_9FIRM Uncharacterized protein OS=Eubacterium sp. 3_1_31 GN=HMPREF0984_01936 PE=4 SV=1 +---LKQQTIQILDEPMEWQQAIHKASEPLLHRAIIKKSYVQAMIDLLYDYGPyiVLANGVAIAHANPE--QGANALGLSLLINKQSITFEDDA-NVHFLFVLSNPDQDKHLHLLRDIMRLANDTALVDQLLKMDDTLAVLEGLKK-- +>tr|A0A1F9ZR07|A0A1F9ZR07_9FIRM Uncharacterized protein OS=Firmicutes bacterium GWF2_51_9 GN=A2Y20_08395 PE=4 SV=1 +---ISLEKVRRVQRVADWQTGIALASSPLLVSNAVEQRYIDTMVANVEKFGPyiVIGPKIALAHALPQ--DGVNSLGFSLLLLDEPVSMMGR--DVSMLFVLAPIDKSSHFGIMKDLMKIISKEEHLRELENMKCEDVISFFEEI-- +>tr|A0A150KJX1|A0A150KJX1_BACCO Uncharacterized protein OS=Bacillus coagulans GN=B4099_0971 PE=4 SV=1 +-LKLTEQNISILSYEISWEEVVDTIFAPLLERNAIEPCYLKAVKSAFykHYQTMLIGPDVYLPHARPDEG--VNYPDIQIVLFKKAVMFPN--HRPVSLMVALAPsADNSHVLTLSKLNDIFLDSKALRQIKSAASPKQLLKIFER-- +>tr|A0A090IT96|A0A090IT96_9BACI Uncharacterized protein OS=Bacillus thermoamylovorans GN=BT1A1_1055 PE=4 SV=1 +-MTIDEKNIILIDNQIPWEDSVDITFSPIIKRGSVDQSYVQRCKQLFfeNYNKMLIGPNVYIPHAEPSNK--LKQPDIQIAVFFEPIYNPD--GSPFHVMVGLVPsNTNIHVPFLLRLNDFFIKKDSIKKLLASKNPREVLALLGS-- +>tr|R2T0U3|R2T0U3_9ENTE Uncharacterized protein OS=Enterococcus pallens ATCC BAA-351 GN=UAU_02565 PE=4 SV=1 +-FQLRIQQFSMIE-ADSWQEVFHFAFGKLLERGSVNERYVNRTLKLFekDYPFMMIAKDCYLPHTKPEDD--VTKPDYQVVLVKNRLQFAN--DRELKIMVALAPsKENKHVEWLLKINHALLQEENICQIEEISTIEDFYELLKS-- +>tr|A0A0M2SI08|A0A0M2SI08_9STAP Uncharacterized protein OS=Salinicoccus sediminis GN=WN59_09885 PE=4 SV=1 +-GLLEEHQIKFVRDK-GIFQMAAKGLNLLKNRGSINQNYFDSTMDIFeeKYQTMIIGPNIYLPHAPVEEG--AIREDYQLLIN----------PSLEKCVLCISPeSNNAHVKKLLELNGLFTDDLFMKRLYKSN-EKDLVKLIEG-- +>tr|A0A1Q8E819|A0A1Q8E819_9STRE Uncharacterized protein OS=Streptococcus cuniculi GN=BU202_05540 PE=4 SV=1 +-ILSSVSQVSIVE-EIEWRQIIHRSYEGIYSRGNVTKNYITKCQQSFyhSYTTQIISNEVLLPHSLPENG--VLEPDVQIILLKKTVIAPN--QQSYRMIIALAPgYENEHVSWLVELNKKLRISKKREEIFNAKTSQELFEKLK--- +>tr|A0A1U9K905|A0A1U9K905_9BACL Transcription antiterminator BglG OS=Novibacillus thermophilus GN=B0W44_12750 PE=4 SV=1 +-DFITPDNITFKHSVSSWEEAIRLAAEPLIDSGKIEPKYVEAMVKHCdQDPYIVINPKVAIPHASPDEG--VHEVSMSLLKLDRGVHFAG--QYCIHVLVVIAAvDKHRHLKALMQLMKLAGSEEDVRHILQAASAEEIRSILKK-- +>tr|A0A1Y3PW00|A0A1Y3PW00_9BACI Uncharacterized protein OS=Caldibacillus debilis GN=BAA03_01135 PE=4 SV=1 +-DLVPVEFIRLQQPARDWKEAILLASRPLLQNSIIEMSYIDSMIRVIqeYGTY-MIAPKVVIPHAKPEDG--AHKLCMSVLTLKNAVRFPK--NIFIQVLIVIAAvDRKSHIKALTQLYDLLMDKNNVETMIGTDNPMVIHRLFRE-- +>tr|A0A212JCK7|A0A212JCK7_9FIRM Putative Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=uncultured Clostridiales bacterium GN=KL86CLO +-----MEFVFISDKADNWEDAIVKTSRALFDAGFVTEEFGSQCIKREREYPTGLGTQipIAIPHTD---SAFVHTSAICVLALESQVPFINMEDSESevpvEYVLNLAIKdGKNQVTILNKVLQVFNREGLPEQLER-KGNGYLKELIM--- +>tr|A0A242IXB0|A0A242IXB0_ENTFC Uncharacterized protein OS=Enterococcus faecium GN=A5852_000812 PE=4 SV=1 +-----MKFKAIELNERSNIEVIKQCGLELLNEGLVGNSFIESCIEREHHFPTGLPVDppVAIPHTF---DLSVKESSVCYARLKKPVTFKQMDTQVDdlavEHVFCMALKdEHTYIEFLQKLILSIQSRNFIVQLSK-CEPEKLVDFLR--- +>tr|A0A0R1YHU8|A0A0R1YHU8_9LACO PTS system IIA OS=Lactobacillus hamsteri DSM 5661 = JCM 6256 GN=FC39_GL001041 PE=4 SV=1 +------DAVFV-SSESNQDELLKNIYDHLLESGYVKGNFLSHIIQREHDFPTGLSTKtlgsdlpnIAIPHTEG---EFVNTRLIVPVALENPIVFGNmikpnEKLEVKFLFMLLETNPDGQAQLLSQVMNFLAKTPesELKNLFSFTDPDAIYEFLTQ-- +>tr|Q97EZ7|Q97EZ7_CLOAB PTS system enzyme IIBC component (Galactitol/fructose specific) OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM +------DLIFI-EDAKDSNEIFKKIGQRLIQKGLVKDNFIDGIIEREKKYPTGMDLSviegqeynVAIPHTER---EYCLSKRIVFVKLKKEVEFKNmiapeDTLKVRYLFMIINNENDAQTNILANIMDFITNKENMDKLNKTDNEEEIFEFITD-- +>tr|A0A1W1ZCS5|A0A1W1ZCS5_9LACT PTS system IIA component, Gat family OS=Aerococcus suis GN=SAMN04487984_1272 PE=4 SV=1 +------KYCYI-TSKESSSEVFEEIGKILFEEGLVTEEFSEQIKIREKDFPTALDISpifsdvsgIAIPHTES---EYVKTQKVIPIKLNVPFKMRNmidpsSEVEVNFMFMILNNDSSGQSNILAKIMSGITSSDkkVLKEIADINNSNDVYKFAKK-- +>tr|W0FTS9|W0FTS9_9BACT Fused 2-O-a-mannosyl-D-glycerate specific PTS enzymes: IIA component/IIB component/IIC component (Fragment) OS=uncultured bacte +-------------RFTSREEAIHALTQRLAALGKISstEQFLEEVYRRESLGPTALGEGFGCAAWQNcCGKRSGGLRVATLSEplQWEGVDGPEAVDLVVLLAIPPNEAGTTHMQLLTALTTRLADDEIRARIQSATTPDELLSALDDK- +>tr|G5IIL6|G5IIL6_9CLOT Uncharacterized protein OS=Hungatella hathewayi WAL-18680 GN=HMPREF9473_03344 PE=4 SV=1 +-----PSLIMTGATAENWEEAFRLAGNLLYREGYIEKGYISCMIQNVRNYGCYmmLCEDVALPHA--KAADGVIKTGFSFVTLKTPVILEHeQETHEIRLVVALAADNRmTHLTAMGELIELVCQDDKKEQLIQAEDAEMFIRLI---- +>tr|A0A1Q9YLB3|A0A1Q9YLB3_9FIRM Uncharacterized protein OS=Faecalibaculum rodentium GN=BO223_04145 PE=4 SV=1 +------DLIFLHQAFEDKETLLRFMTAWLEEKGYCSSGLYQSALRREQLTSTSIGSSIAFPHGDPEY---VNESHVVLMTLEKPMLWdGEEMADIIF-FAAFNMNSREEKRRIemfyKELIPCISDREFMTMLKTARDSVQLYKD----- +>tr|A0A0A2VZM4|A0A0A2VZM4_BEABA D-methionine-binding lipoprotein metQ OS=Beauveria bassiana D1-5 GN=BBAD15_g902 PE=4 SV=1 +---------------QDWRHAMQLAGDLLTKNGYTTNDYTKEMIHAVD----TLGPYIVVAPGIALAHsrpaPSVIKTGLSVTTLVEPINFGSEENDPVEIVFGLCATdSHSHIQIISRLVAFLDNEENIEFLKRCTNSSDVW------- +>tr|V5F357|V5F357_PHOLE PTS system, fructose-specific IIA component OS=Photobacterium leiognathi lrivu.4.1 GN=PLEI_3398 PE=4 SV=1 +--------IKINLNATSKEELFQELVNVLHTNNRISDkaQFLADIQQRESDSI-TCMDGIAYPHAKSKA---VLEPAIAVGIKKETIAYGDEDGVEPSLFFMIASPDngaDHHIYVLQELFGKFGDE-FLEAMHNATSEQQALDVL---- +>tr|A0A1S8T8J8|A0A1S8T8J8_9CLOT Putative licABCH operon regulator OS=Clostridium puniceum GN=licR_4 PE=4 SV=1 +-------LFFYGLNMNSKEEVITFLSKELLRNGQVGTEFANSVFEREKISSTTFENGIAIPRPI-SNCF-CYKTIISVVILKKPILWDGQK---VKCIFLLSIREKDKKY-LIRffdLvVEHLSNKFNIEKIMEANTFDKFASII---- +>tr|C7XLV3|C7XLV3_9LACO Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Lactobacillus crispatus 125-2-CHN GN=HMPREF5045_02014 +------DLIDLSASVSDEQELFDLVGTRVIEKGFANLGYISGLEKRELSYPTGLkfpEIPMALPHVDPKY---IKKPFIYVIRNDKPIDVKqmgDSADmQSSNfLFLGLK-DGAKQPKLLAEIMAAFQNKQFVSAFQNADDKEAMYNLLT--- +>tr|A0A1T5L0G1|A0A1T5L0G1_9CLOT PTS system, galactitol-specific IIA component OS=Maledivibacter halophilus GN=SAMN02194393_02267 PE=4 SV=1 +------DLVFFDIETKSREELFLKIEEFLVEKKYAIKGLGQALIDREKEYPTGLalkGINIAIAHADPKY---SLDNKICAIKPQDKIVFQnieNLEKlNIDLiFILLLK-DSGNHLNILRTISSVFLDDDFIAAVKETKNSQELFQVLD--- +>tr|G7VXX9|G7VXX9_PAETH Transcriptional antiterminator OS=Paenibacillus terrae (strain HPL-003) GN=HPL003_01865 PE=4 SV=1 +---------IISnSQFTDKCEPIDYLCDLLLKNGCVKEDFYSKVVSRENSVSTGYD-GFAIPHA---ISLDAVSNEIAVLISPSGIKWDN---QNVYVVFMM-SVSPDTLvdfqELYAGLSLLLTETSVIGRLRKCKTFEQFKEIL---- +>tr|A0A139SLZ7|A0A139SLZ7_9BACT Uncharacterized protein OS=Cephaloticoccus primus GN=AXK11_06155 PE=4 SV=1 +----SPELLTLDLRATEHEAALREVAEPLRAHPDMRdyDRFFEQVIERERLDSTYLGNSVALPHARTSHvGRVVLAVG----RSAAGLRFENCES-PVHLLfvLGTPTSsPGDYLRVVSTLCKILASADNRAALLSASTPAAFLAAITT-- +>tr|B4D8Y6|B4D8Y6_9BACT Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Chthoniobacter flavus Ellin428 GN=CfE428DRAFT_5376 PE=4 SV=1 +----RPDHIALQTRAKDPKSAIDEVAGLLKSVPAVLdfQALLKGVQSSAPClPEPGGGFALCIPHTRGECvNEMVMSVG----RSEAGIVFPNVEL-PVRYVfcIAVPRAlAADYLRIVGLLARVFKDRTSEAELRAATTGTEFVDLLSR-- +>tr|A0A0C1RT36|A0A0C1RT36_9BACT PTS fructose transporter subunit IIA OS=Methylacidiphilum kamchatkense Kam1 GN=A946_09580 PE=4 SV=1 +----TQDRVLVNLSAKDKFEAITKVAKILEHSPLLQsfDAFLEAVLEAEKSGLTWFEQEVAFPHIRSQVvKELVIAAG----FFPSGVLFREAAP-LVRLIfvIGAPKKlNTNDIIVVGALARIVA--TNRQQLLKAKSAEEFVSLIAS-- +>tr|A0A1G3ZG03|A0A1G3ZG03_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium RIFCSPHIGHO2_12_FULL_41_10 GN=A3F67_10020 PE=4 SV=1 +----LLESINLSVKAKEGNTALKEVMKLLQYDPRVShwENFCQSILERPLFsLRANDQAAIMIAHGRTSSvRDLVMAAG----RNTQGITFHESEQ-PVLLLfiVGIPHElSTEYLRIMGSIARACGNPETLEKLLSTENSHDFMTTLSS-- +>tr|A0A0R2AFP4|A0A0R2AFP4_9LACO Uncharacterized protein OS=Lactobacillus vaccinostercus DSM 20634 GN=FC26_GL001418 PE=4 SV=1 +---LTTTNIVinDSPHAESWQYAIQHAFNNMLENHSISQSYVDKIIALTQQkgPYMYLGNGVFLAHAA--PQDGVKEIGLSLYISKIPIALTTSnhPQKNVNIIIGLAPIDqSSHLKVLSELFQNIQNKDWLEHLKSATTVTQVLEQIK--- +>tr|A0A0R2M295|A0A0R2M295_9LACO Uncharacterized protein OS=Lactobacillus paucivorans GN=IV54_GL000772 PE=4 SV=1 +---LTPDHIHVTSRILTWKQAIQRSFLPLLSGDYVDKSYVTEIIRKLEKngPFMIVKGGVLLAHSA--PSSKIHKLGMSLLELQHPVKMGDK---TITTIICLAPKReKQHLKALSDLLDILEDDDKYETLIHSERKSELVTLMA--- +>tr|A0A0R2BTL0|A0A0R2BTL0_9LACO Multidomain protein OS=Lactobacillus coleohominis DSM 14060 GN=FC35_GL001335 PE=4 SV=1 +---NATYTTDVIQQNTDWKNAIQISLKQLEYQNIITDEYINKIIELTESngDYMAIGKGVFLAHAA--PKAGVKHLGFSYTLFKKPFFIQNS-SKPINFVVGLAPVDqQKHLHILGNLLQFIQNEQLMDQLHKIKNYKELSMLLR--- +>tr|C9KLV3|C9KLV3_9FIRM PRD domain protein OS=Mitsuokella multacida DSM 20544 GN=MITSMUL_04187 PE=4 SV=1 +---SGEIPAAAKHAKPAWQNAIQYACQPLLQGHFIVQSYIDRIIALLARygDYMVLGKGVLLAHAK--TKDGVLASSAALTLFEKPITM-QS-GKEIRCIICLAPQNqNDHLDFLALLLQKLNDTEWCKTLFTRNSQQELESFIW--- +>tr|D3LAX1|D3LAX1_OENOE Uncharacterized protein OS=Oenococcus oeni AWRIB429 GN=AWRIB429_1501 PE=4 SV=1 +---FTKSNISFVDHANNFREALSLAFEPLIKNRSIETKYIDKIEYLTKKygPYMMIEKGVLLAHAK--PGDGVNKTDFSFLLLKKPVHLVNNnDSEAIKIIIGFATVDtSSHLEKLNDIMKILQNGKAMNNILSVSKKEQLLENSL--- +>tr|A0A0D0FFQ4|A0A0D0FFQ4_LACBR PTS system, IIA component OS=Lactobacillus brevis GN=N624_1572 PE=4 SV=1 +---ISEDHIQVLAGVSDWTVAVHQALRPLEIAGIVDPDYANHIIEATQTngPYMVLKEGIMLAHSK--PTDGVNELGMSVLVLKTPVVLSAHgQQRSLRVIFGLAPTDrQTHVQALSQLLALLQNEELYQRLILADNHDEVHHVLV--- +>tr|G7M425|G7M425_9CLOT PTS system transcriptional activator OS=Clostridium sp. DL-VIII GN=CDLVIII_4266 PE=4 SV=1 +------ELIQIRDDMLTKSDLIDEMCKLLISKGKVTEEYIISVYKRELMGGTLFDGTFGIPHGL---AEFVKKSSLAIFKLNNPILWDYD--CEVNVVIMLALK-EGDMKIVRSLFDTISMADIADGIKKAGSIKEISNLLL--- +>tr|R2T3Z8|R2T3Z8_9ENTE Uncharacterized protein OS=Enterococcus pallens ATCC BAA-351 GN=UAU_01856 PE=4 SV=1 +------SLIFMDQDIQTKAAAIQFLADQLVAQGYVKPKFSETVFEREDMVPTCLETGAAIPHGYF--S-EVNVPQIAVLFPRKPIAWGNQL-A-AKVVLLLAFT-EDTSPVFSQIYSVISDKQAVEALTNLQSKEDVQACLD--- +>tr|U2TDZ2|U2TDZ2_9FIRM Sigma-54 interaction domain protein OS=Mitsuokella sp. oral taxon 131 str. W9106 GN=HMPREF1985_01205 PE=4 SV=1 +------SNIVCGLGFSDKTQVMDRLAGLLQQHGAVEAGFLLSAYKRESTGATYLSGGIGIPHGD---AKYVKRPAIAMACLERPVLWENN--FMVDLVFLLALR-EDDQKYVNAFYRILSNKDTLSKLKAAKTPAECLTVMI--- +>tr|W6NIT1|W6NIT1_CLOTY NtrC family Transcriptional regulator, ATPase domain OS=Clostridium tyrobutyricum DIVETGP GN=CTDIVETGP_2012 PE=4 SV=1 +------NIVKLFYSIGSKEEIINIMARSMERKNYVRHEFYEDILDREDLGSSYIGNGVAIPHASY--ERNIIKPVIAVAVLKNPILWEEG--NKVDIVFILALN-GNSKKSFLKLFKTIKNTDLIESVKDMNDSKSVINKIF--- +>tr|I8RMK2|I8RMK2_9FIRM Sigma-54 factor interaction domain-containing protein OS=Pelosinus fermentans B4 GN=FB4_2527 PE=4 SV=1 +------ELIFYPNPEWSKPQVIDLLTQSLLSRDLVKPEFATDVVKRELIGVPILSLRVAIPHGED--PRYVNQTSVALAIFPEAIPWGEN--YRVNVVCLFAAA-TDGRELVQELGGKLTNDEIVDCLIEARTPAEAKRILV--- +>tr|E4RM19|E4RM19_HALHG PTS system transcriptional activator OS=Halanaerobium hydrogeniformans GN=Halsa_0651 PE=4 SV=1 +------NLIYLSPGFNSKKEAIEFLSKKMIVSGSAKDTYYNAVLEKENQGVTYVGNGIAIPHAES--K-HVNYSQFAIAILEEPIDWSGFE-V--DIICMFAFK-DLKTDHFKEFYNRLQKNiDYIKN----ADNIDLIKEVL--- +>tr|A0A0J1FJC5|A0A0J1FJC5_9FIRM Nitric oxide reductase transcription regulator NorR2 OS=Peptococcaceae bacterium CEB3 GN=norR2 PE=4 SV=1 +------DLLLPQVFSKNKENVLQSLADLMISHGYASAGYLESVMEREAFGLAVFSSRFAVPHASD--PTLVRRSGVALAVLKEPLSWGEGL-T-IDVVCMLALT-VSDAEIVYELSDLANRPERLEKLYTAKSREEMFQVLS--- +>tr|M1ZKA4|M1ZKA4_9FIRM PTS system transcriptional activator OS=[Clostridium] ultunense Esp GN=CULT_230015 PE=4 SV=1 +------DTIWPKAVFKTKMEVLDKICGKLYDRGYVNDDYKMKVYERELLGSTIYKNSIAIPHAT---TEETIKSTLGIVTLDNPVLWSED--YYANIVFFLVFK-ENCSEILSLLHSMANNKALLENILKANTSDDILHMIL--- +>tr|I8RDG9|I8RDG9_9FIRM Sigma-54 factor interaction domain-containing protein OS=Pelosinus fermentans B4 GN=FB4_1184 PE=4 SV=1 +------DFIMIDLACKTKQEVIETMSMVLFNNGFIKKGYIDSVFERENMSSTCFKKNVAIPHGLP--S-FVNETSIISAKLSQAIEWDDSK-NLVNLVFLLAVK-DDDINIINDLFRLLKQKNNIDEFLKAKNRFEFIKVLY--- +>tr|A0A0R1M9L7|A0A0R1M9L7_9LACO Transcriptional regulator OS=Lactobacillus capillatus DSM 19910 GN=FC81_GL000828 PE=4 SV=1 +--------------SVHaleqsetltEETSQKYLDQYFTF--inpnkitKILWDYCDFIQQHSDFIISNTFRVSLIMHLAG--A-------------LERYLTRSEV-E--------------VDQQKIvaiksdKLYASIKQAnELLDKTLNIKITEGETYYLV--- +>tr|A0A174I021|A0A174I021_9CLOT Transcription antiterminator OS=Clostridium paraputrificum GN=luxO_4 PE=4 SV=1 +--------------ESLiidvnrdmvLGAAADVTSKYLQC--ldvekvhPYLVDFISCIEHSNIFKLALNEIASTYVHVCC--M-------------IERILLCNNI-L--------------KSDENLeevkaklfTEFNFIKRAlRNIEVGFSIEIPDDEIYYLL--- +>tr|W7CSS1|W7CSS1_BROTH PTS system transcriptional activator OS=Brochothrix thermosphacta DSM 20171 = FSL F6-1036 GN=BTHER_00085 PE=4 SV=1 +------MV---------LQMSEESLNEFLTY--lnpskilPLLRAFIDDIELFEEINLTNGQKINMMVHIGC--A-------------LERCVLKETL-T----YYSK----PSPSQL--SKVVDYQTIaLLFSTSLQIKLPDSELFYLM--- +>tr|A0A139TGX4|A0A139TGX4_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Candidatus Stoquefichus sp. KLE1796 GN=HMPREF3037_0119 +------QCISILSGNYTkeevidnavAMMVEANCVDENYL--lsvykreAWLPT---YLQGGIGIpHGESQYVTKPVIHITK--L-------------DKPVCWDGEN-F-VDFVFTLALK-EDQTEAFEelykqmrePSFMQIlklcTSQeDILEKFMLIQY------------ +>tr|A0A174R4R0|A0A174R4R0_9CLOT Sigma-54 factor interaction domain-containing protein OS=Clostridium paraputrificum GN=qseF_2 PE=4 SV=1 +------DM---------CGKIIEAFKGEIKT--ydlastkDELIQFIYNVEEKFGLTLNLDTIVGAIMHMIS--S-------------IDRIKLGEHV-E----KYIA--I-DKL-SIDKEEISKIKEIlKPIEKKCDMEFVDDEIYYVY--- +>tr|C6PVA3|C6PVA3_9CLOT PTS system transcriptional activator OS=Clostridium carboxidivorans P7 GN=CcarbDRAFT_2720 PE=4 SV=1 +-------F---------YNEIFQSLGNEIKE--lsmsdfkPLCINFLDNVRENITDNIDIYMVSGLILHLAC--A-------------IIRLINKEDT-P----KCIR--K-QKV-MSYSKEYNFLKESlRPIERFYNIKFSDDEFCHIL--- +>tr|U2N0F1|U2N0F1_9CLOT PTS system transcriptional activator OS=Clostridium intestinale URNW GN=CINTURNW_3780 PE=4 SV=1 +------LV---------QNQVFDAIKDDLEI--lyietykKYFNVFLENIRERLNIEFDLDMFVALTFHTTC--A-------------ISSIIKNNKR-K----VCKS--K-NDFKSKYQKEMDIIKEElSSIERVYSINIDEDEICFIL--- +>tr|A0A0U9HGA2|A0A0U9HGA2_9THEO Transcriptional regulator with an AAA-type ATPase domain and a DNA-binding domain OS=Tepidanaerobacter syntrophicus GN=TSYNT_91 +-----------------IEQMKEVVKENTSIDSekyikdfiTF-----YKSLKKHNIILNEDMIVGFILHISC--A-------------IEKIQTGTFK-P----KINTAQI-SFLKEKYPEDFKTVASAlESMEKSFNISFPDEIYSNLV--- +>tr|A0A0U9HFI5|A0A0U9HFI5_9THEO Transcriptional regulatory protein LevR OS=Tepidanaerobacter syntrophicus GN=TSYNT_8113 PE=4 SV=1 +------------------KKIEQSLCEHLKA--vnaeecfRMSKSSVINISKALGLLIPSEVKIGIILHMAF--L-------------IEKLASGGKR-A----IFEN--L-QEYEKRHKKELVILENHlKPLEDYFNIDIGPHEYAYLC--- +>tr|R8PWL6|R8PWL6_BACCE Uncharacterized protein OS=Bacillus cereus VD136 GN=IIW_03909 PE=4 SV=1 +------------------------LGQQMQR--ddgalmiKTIRYALNTIQELISLQLNSDSLMGVILHMSC--M-------------IDRLQKGEKL-L------PYPDK-EARRQDEYWMYMKVKKAlQPIENTFDVQIPDDEVFYVM--- +>tr|A0A0K2M871|A0A0K2M871_CLOPA Transcriptional regulator OS=Clostridium pasteurianum NRRL B-598 GN=X276_02635 PE=4 SV=1 +------------------INLPKIIKENIYN--idgvelyKDVTLFLNILQEKLLIKLSDENMVGVILHLSF--V-------------IGRLRNEDNP-A----VYPQ--K-ENYLEENINLYNIIKENlNFITSKYKVEISDDEICYLM--- +>tr|T4I2J1|T4I2J1_CLODI PRD domain protein OS=Peptoclostridium difficile Y384 GN=QQG_1039 PE=4 SV=1 +---------------------VEGLKTSLKS--snynrifKDIKYVSDELFLVFNIEKKYDKVIGLMMHLAF--M-------------VDGLIGNTRE-I--------------EKLDKEktldyhKSLSKIKDIvSQLDKKYNIEINEKECYQIL--- +>tr|A0A1G4FHJ3|A0A1G4FHJ3_9FIRM Transcriptional regulatory protein ZraR OS=Sporanaerobacter sp. PP17-6a GN=zraR_1 PE=4 SV=1 +------DLIFVDKGFKSKEEILNKALCSMEQKGYVTSEYKWSVFERENLSPTLLNRYVAIPHGD---PTEVKRESIAVIKLQNSIEWCEN--IKINIIFLLAIN-DYGREKFKRLFKLVNDKRIFNRLQICKTKAEIKEVIV--- +>tr|A0A0K8JB96|A0A0K8JB96_9FIRM Uncharacterized protein OS=Propionispora sp. 2/2-37 GN=P22_0659 PE=4 SV=1 +------AKIIMAPAGKNKQELLRLLCDGIISEGYVNAGYYEAVLERENMGSYVIRQKVALPHAD---SSYVNHSVVVIAKTPEPIEWDEE--SSVSIICLLALD-INGKDGVRYLYNTFKNDNIVAQLEQAQSEQEIREVLL--- +>tr|A0A0K8JBZ5|A0A0K8JBZ5_9FIRM Uncharacterized protein OS=Propionispora sp. 2/2-37 GN=P22_0904 PE=4 SV=1 +------QNIYINLPYNNKKDVLTFLCNGLIQHKAVTAEYLLDVFQREEIFTTELDGGVAIPHAD---ESHVLASAISIATLKEPILWE-Y--KQVNIVVMLAVD-KHCFSALSSLLGFIVKADF-QKIVQLPSGRAIKEAIV--- +>tr|A0A0K8JBN2|A0A0K8JBN2_9FIRM Uncharacterized protein OS=Propionispora sp. 2/2-37 GN=P22_1075 PE=4 SV=1 +------RLIRIFHSLASKEEIIKIMTGVMCKERYVNEAFYNDVMEREAWATSYIGDGVVIPHTAT--TVNIIKPGIAIAVIKNKMDWDDAE-V--RIVFVLALK-TEHKDLFLRLYNVIKETDMVEKVCGLSDSKLMIAEVL--- +>tr|A0A1E6VFW4|A0A1E6VFW4_LISMN ArsR family transcriptional regulator OS=Listeria monocytogenes GN=AJN46_08495 PE=4 SV=1 +------------------EKLIASLEGNLQA--vssaeqlvYFLRKVISELQLQLNVILESGVDIGMILHLAF--L-------------IERVKLGAVD-R----EFPD--L-NEFAKNHMVEMQITQQMmENVEIEYDIVIPQSEIAYLT--- +>tr|G6B2D6|G6B2D6_CLODI Sigma-54 interaction domain protein OS=Clostridioides difficile 002-P50-2011 GN=HMPREF1122_00003 PE=4 SV=1 +------NL-SY------NSLIINFMTQNLEL--ldsvklfNYVNSSLFTIIELIDEDLKSKFKLGYILHCSF--M-------------IERCFKNTTF-PYNNIT--------ELI----sknhELYSLIREAfKPTEAYFNILIPDEEIAYII--- +>tr|A0A1E5GGU5|A0A1E5GGU5_9ENTE Transcription antiterminator BglG OS=Enterococcus ureasiticus GN=BCR21_06305 PE=4 SV=1 +--------------RTMkdqiakryvHGLSLKAIVNHITV--lnpqrlsIEVSQIYDDLCRQLNLSSDEKIMLRFLIHTCC--T-------------VERLVINNEY-S--------------TSDYNVsykdipNEASVIKMAfRPLEVSYNVQFSPLEIKYIY--- +>tr|A0A1B8RM12|A0A1B8RM12_9CLOT Uncharacterized protein OS=Clostridium paraputrificum GN=CP373A1_13885 PE=4 SV=1 +-----------------deikndiiKFFSLQNILNQLTI--lnpdkivDEVDKIINNYEISLNKKFEGDLKLALFIHISM--L-------------IERLVLRENI-T--------------SHPDEEkfkqchsDFIELSEEIfRDVLKEYRVSLSLAEIVIIH--- +>tr|A0A1M6H7R5|A0A1M6H7R5_9CLOT Transcriptional regulator containing an AAA-type ATPase domain and a DNA-binding domain OS=Geosporobacter subterraneus DSM 1795 +------ELMHLNVMAANKNEVLDRMANRMVENGYVTERYIFSIHEREIMAPTVFKNMVALPHGS---PEEIIQPAISIMTLSSPIIWDGN--QTVDCVFMLGLS-QYYKKEFRKFYSIINNEKVLEKIKKCKTVDMLMEVLL--- +>tr|A0A1M6IE13|A0A1M6IE13_9FIRM Transcriptional regulator containing an AAA-type ATPase domain and a DNA-binding domain OS=Propionispora hippei DSM 15287 GN=SA +------ELVLVHPAVQGKEAVLQSLSDLLIGQQHVHENFLEGVYQREILRPTYMGNGAAMPHTD---PSFVKKPGLAIAKLATPIDWN-G--KPVQLVYMLALT-EECQTMIKELYSLICSQDFLSAVQQVKTPEQFIAAVH--- +>tr|A0A1M4U2H5|A0A1M4U2H5_9FIRM Transcriptional regulator containing an AAA-type ATPase domain and a DNA-binding domain OS=Alkalibacter saccharofermentans DSM +------EIIYMNKEIATKDEAIKFMCSDMLIKGYINESYLDGVLQRESMCPTFTENLLAIPHGY---CEDVIKPGVGIMIPKDPVDWGNG--RFVSIILLLALN-DEAKDEFQWIYKIITDREIVKKIKNQNSSRKIVEIFN--- +>tr|A0A1M5VLR4|A0A1M5VLR4_9FIRM Transcriptional regulatory protein LevR, contains PRD, AAA+ and EIIA domains OS=Sporanaerobacter acetigenes DSM 13106 GN=SAMN02 +------DE---------ENMYIEMLERVLVF--lnpiktyTIIKATFDYIVNKENIPIDDCLKVSYVVHCSC--M-------------IERIFLEESL-Y----YKEI----DILIEKEVELYNTIKKAmEIIEQSFSIYVPDTEIGYII--- +>tr|A0A1L5ZYF4|A0A1L5ZYF4_LISMN PTS sugar transporter subunit IIA OS=Listeria monocytogenes GN=BTR18_11270 PE=4 SV=1 +------IA---------KEIIEESLNEFLTY--lnpkktiEILSSFASVLEKKLGYKLDNTFKINLLIHVGC--A-------------LERMVLNDGL-I----YREP----KDMLET--NIFKALEQTnKEVIYKMNLKLTNDELCYLY--- +>tr|A0A1L8T298|A0A1L8T298_9ENTE Transcriptional antiterminator bglG:Sigma-54 factor OS=Enterococcus dispar GN=RV01_GL002586 PE=4 SV=1 +--------------TYPseaiqgekaVELINRFIHENFTF--ingdklaQPIWDFVTNLVEDVGLsTRDFGLEINLALHTAG--V-------------LERVLLKQPL-A--------------VTTTEAeqllneSLYEQVHNHiQSFGRMLRLNIPPSEEYYVL--- +>tr|A0A1L3SJ16|A0A1L3SJ16_BACIU PTS sugar transporter subunit IIA OS=Bacillus subtilis GN=BAX60_19000 PE=4 SV=1 +------AN---------iivRELCEDSLKKYLVF--lnphhiiEMLLEWLQTVQDELGAIFNNAVLIKVIMHTAF--A-------------FERVIKQNPI-AFSEE--------EEINDQMKEMVNVTERTlAPYEQKLGLRISDDEKLFIA--- +>tr|A0A1L8TNV4|A0A1L8TNV4_9ENTE Uncharacterized protein OS=Enterococcus hermanniensis GN=RV04_GL001706 PE=4 SV=1 +------------------PEMVDSLTNDFTP--eldvktlfLMIDDVLKLLRRDNELIIENTAIQALSIHIAF--L-------------VDKVKKEEER-P----LFDD--V-KYFHQENILFFNQVASKlSLIENQFSVRFTEDDIAYIV--- +>tr|A0A1M6GVS9|A0A1M6GVS9_9CLOT Sigma-54 dependent transcriptional regulator, gfr operon transcriptional activator OS=Clostridium amylolyticum GN=SAMN05444401_ +-----------------dkinrevvKLFTLENVLNYLTI--lnpdkiiDQVEEAIYTLELGLGFRFQNDLRISLYIHISC--M-------------IERLVIKDPI-M--------------TYNKFQefeqchgHFIELVKKAfSVIEHFYKVEIPISEIGFIY--- +>tr|A0A1L8R2C2|A0A1L8R2C2_ENTAV Sigma-54 interaction domain protein OS=Enterococcus avium GN=RU95_GL004375 PE=4 SV=1 +-----------------evvnnemiKNLSLNKIIDSLTI--ldsnkiiTQIEPCLDSLERYLNRQLNNSQKLNLYVHISC--M-------------IERLMRGKKM-D--------------SFPKDGyfgenqeQLGSLISTAfRPIEQLYNISLPIEECYYIY--- +>tr|A0A231VKZ5|A0A231VKZ5_THETR PTS sugar transporter subunit IIA OS=Thermoanaerobacterium thermosaccharolyticum GN=CE561_03490 PE=4 SV=1 +------AV---------RNLCRDSLNQFLTF--lnpdkiiNLLIRFCNRLEIELNKQFSNTMKIKLIIHTGC--A-------------LERTIINDSI-K----YKDS----VLNLNR--GIIEKVRNCsKIFSDALNINLIDDEIYLIA--- +>tr|A0A231VLX6|A0A231VLX6_THETR Transcriptional regulator OS=Thermoanaerobacterium thermosaccharolyticum GN=CE561_02695 PE=4 SV=1 +------------------VKMGNVLKENIDN--idgeelySDIQNTIMKLCDTLSICFDDDMLLGIILHFAF--M-------------VSRIKKGEKS-I----EYIG--K-DEYIKSNRSLYNAVKKAlTHLNTKYSIIIPDDEICYIM--- +>tr|A0A1Y4WSS4|A0A1Y4WSS4_BREBE Transcriptional regulator OS=Brevibacillus brevis GN=B5G50_26470 PE=4 SV=1 +------------------LKMQESLGEHLQM--vdgqdilADVRMCVGRMEERLNNYLVFDTRIGAYLHICC--L-------------VDRLKTGTQS-V----AYIQ--K-DSFLLENRKLYSLIRHElLPLEDKYEVVISEDDVCFIM--- +>tr|A0A242L8D0|A0A242L8D0_9ENTE Uncharacterized protein OS=Enterococcus sp. 6C8_DIV0013 GN=A5798_000768 PE=4 SV=1 +--------------------LSASLDGAIKS--vpslyellSETKKITEKIENDLSLVLEPGVDMGIILHLSF--L-------------VDNLLTDKHP-RLF-----------NELAEFKktyrYEMDIVKMNlIIIEKKYNIELPEDEVAYVT--- +>tr|A0A242AW76|A0A242AW76_9ENTE Uncharacterized protein OS=Enterococcus sp. 7F3_DIV0205 GN=A5821_001250 PE=4 SV=1 +------------------EGMRLNIATMLEY--kdgenliLSIREWVETMAAEINPAISYEIKIGLSCHIVC--M-------------IDRLKQGKNV-S----TFPQ--T-LTFKEKYSNEISIVQKNsQFLEAYYAISIPKDEIFYIT--- +>tr|A0A242LL83|A0A242LL83_9ENTE Sigma-54 factor interaction domain-containing protein OS=Enterococcus sp. 7D2_DIV0200 GN=A5884_000490 PE=4 SV=1 +--------------EA-qkmdesvaRKICMDYMEESFTF--inpkkiiNPLWEFADIIRTKLDLQLDYSFYVNLVMHLAG--M-------------LERVLQHDTL-S--------------LTQEELdqitsePSYDVVMKAaLYLKQLFQLELPMEEIYYII--- +>tr|A0A242B0Z3|A0A242B0Z3_ENTFC Uncharacterized protein OS=Enterococcus faecium GN=A5809_002284 PE=4 SV=1 +---------------GSshsftrnivFDMGIEAVDKYLYL--lagnkiqKSLMDFIEELECTFHKKFTYSILLKLLIHTAC--L-------------IERTLINGHE-L--------------KIISEDdtrpshEPIFHVKKAfKNIETEFGITVSYDECFFIY--- +>tr|R6RHI2|R6RHI2_9FIRM HTH domain-containing protein OS=Anaerostipes sp. CAG:276 GN=BN583_02313 PE=4 SV=1 +------EYCRFDAETDDWKEAIAMACEPLIKNGLVKPEYVEEMIHIvQNLGNYMvFIPEIAFVHGRK--D-NVRENCISLMKLKHPIDFGSKAKVDVKVIIVLGNITEN--ENLADLVRILAWENNMERIKHISSYEELLSLRS--- +>tr|B6FXG1|B6FXG1_9FIRM PRD domain protein OS=[Clostridium] hiranonis DSM 13275 GN=CLOHIR_00560 PE=4 SV=1 +------SNAAFLYDADNWRDTIAEASKPLIKSGAIKEEYVDDMIKAiEDLGTYMvFIPEIAFVHASN--K-NVVNNAVSMLTLKNEIYFGDNSEVRIKSIVVLANKDEN--KNLIELINILTKNNNAEKFKNAEKYFDLKIMV---- +>tr|A0A1T5M7S6|A0A1T5M7S6_9CLOT Transcriptional antiterminator, BglG family OS=Maledivibacter halophilus GN=SAMN02194393_04059 PE=4 SV=1 +------DFVTLKYDCKNWREAIFAAADPLLKKGYIIEDYIRAMIEAvEKMGPYMvIIPGIALNHALA--EKGVLKDCLSLLTLKETIDFGDKDSESVKMIIVFGTNKSNkYFKILTDLIKVLEKKENIKKIYEAGNYEEIMDLSN--- +>tr|A0A1Y0L122|A0A1Y0L122_9MOLU Pentitol phosphotransferase enzyme II OS=Spiroplasma clarkii GN=SCLARK_001143 PE=4 SV=1 +-------AVYLDNDSDDWIKNLKLGIKPLIADGVIDELWIEKLIQtTNKLGPYFvFSDLLAMPHISPDSSTK--KLATGFIYCKKPLKFFGNgYEKTCQIIVPLVTtDANSHMELLAQLVSLWNDQDFIKKL----------------- +>tr|G5F1I4|G5F1I4_9ACTN Uncharacterized protein OS=Olsenella sp. oral taxon 809 str. F0356 GN=HMPREF1008_00228 PE=4 SV=1 +----RPDLVSLGEDFATKDECLDAMLCQLETMELVQDGYRRSIFDREQMGATALESGVAIPHAAPE---EVRESSVSVMGLSQPLDWDGVS---VELVILVSLAEQdvDDfRDVITEVYKMTGTHELVHELASVPSAEEFASAFQ--- +>tr|F5YI41|F5YI41_TREPZ PTS system IIA component, fructose subfamily OS=Treponema primitia (strain ATCC BAA-887 / DSM 12427 / ZAS-2) GN=TREPR_0959 PE=4 +-------GGFSPVPGSNPQELLTNLIRGLTLPRSVDaPTLLEAVLEREALMPTAIGHGIALPHPRNPLISVPGEQFVTIAYTGQDLDWNALDGkPVHTVILMVSASAKLHLHTLSRINFFCHQESFRELLTNRVSRDDFIRAIEE-- +>tr|F2NS67|F2NS67_TRES6 Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Treponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091) GN=Tre +-------EVLEDVPGNSCAKIFEYICDRIVVPSGLTaHQLQKELVEREKVLSTAVGNGIAIPHPRYPLVKNSSESKIVVAYLREPMDMQAPDVrKVYVMFVILSDSAQFHIKVLSALATLFKNEKFRKGIQACPSKGELLDLLRR-- +>tr|F4LLM4|F4LLM4_TREBD Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Treponema brennaborense (strain DSM 12168 / CIP 105900 / DD5/3) GN=Tr +-------GVFYGVPGAAAADVYAFVCAHADFPAEISaDVFCRELISRDALMSTAVGNGIALPHPTHPLLKDASLQRIFLCFPERPLDMNAPDGrPVSSLFILLTGGSRCHLDILSQLANLFQKTSVRHLLERQADKNTLLAEMRK-- +>tr|A0A1V6EAE8|A0A1V6EAE8_9SPIR Nitrogen regulatory protein OS=Spirochaetes bacterium ADurb.Bin110 GN=ptsN PE=4 SV=1 +-------ETWFIADPQNMSKVITALVFAAPIPSSINhKVLIDALLSREEMMSTAIGNGIAIPHVRLFDSTNLKEDIVVVAYLFEPVDWKAPDGkPVHTLFFVLAADETRHLQILAEIAQLASDEDFVDFLKTMPSREALIERIRQ-- +>tr|A0A061JD75|A0A061JD75_9CHLA Nitrogen regulatory IIA protein OS=Chlamydia suis MD56 GN=ptsN_1 PE=4 SV=1 +-------------LVDSKEEALQYAARYIANKFELDAGVLFEMlMHRESLMSTGIGEGIALPHAK----DFLLNIGydIVVPVFLSqSVEYKALDGkPVDKLFFLFANQDRNHLNLV-------------NKIVHLGMSLEARLFLA--- +>tr|C6JQ41|C6JQ41_FUSVA CBS domain protein OS=Fusobacterium varium ATCC 27725 GN=FVAG_00122 PE=4 SV=1 +---LDPQFIFTDLKGKNPEEIITEMIERLSLKdkkiNELKDVIVKSVIKREKEISTGMGNGIAIPHARIENFNDFI---VSVAVLEEPIeveIAATHRTDKVKLVFliiSDVLKNKNILKVMSAVSKMaLKRKNLLEKIKEEKNPNKIVEYIQE-- +>tr|D1AJX9|D1AJX9_SEBTE Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_0151 +---ISKELVFLNTESENVEELINNILDKAAEVdeevRNNLDKAKKAVLKREDETSTALGHGIVLPHGRIDGYDDTT---VISGTLKKPMkaiV--RNKEESIELFFiilSGLTKNRTVLKLMSLVSYLg-HQNEFLEKVKGVKSEDEFIELIQE-- +>tr|A0A0S8GCM9|A0A0S8GCM9_9PROT Uncharacterized protein OS=Acidithiobacillales bacterium SM23_46 GN=AMJ84_09655 PE=4 SV=1 +---LNEEHVLVAPPVESKEEATKQLLATFEPDldl-AARERAFKQLLEREKRITSYIDHGVAIPHAKVEGLTRVL---VGLVTSNEGFna--QDPPGATIHLLFlilTPHEKNTLMLQALAAVARLc-HTKEMRETLRRAKTPARIIKQIED-- +>tr|A0A1G0XDS0|A0A1G0XDS0_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_45_14 GN=A2020_05830 PE=4 SV=1 +---LQREAIVTGINetGGDKRSIVAGMLDTLFANtglkdeGIEKSVLLDAIMFREEELTTAIGEGFAFPHARINETLKgSY---MLFGVSPGGVAFGSLDRKPVNFFLmsiVPGANSDMLLKSRAAFMRVm-NIPGIREKILSM-GTGEIWELLDK-- +>tr|A0A0S6VVJ8|A0A0S6VVJ8_9BACT Nitrogen regulatory IIA protein OS=Candidatus Moduliflexus flocculans GN=U14_00488 PE=4 SV=1 +---IDPKLIVVNMTATTKEEAFTALIDHAAHLdaefARQKPAIQTAIFEREQSISTAMGNGVAMPHARVEGYDNVI---VVAGVLKHSIeceLA-SKERGNVRLIFlivVGKTKNKLMLQLMAGITKLt-ENRQLFDAICREASPEKIAALIKD-- +>tr|A0A0R1VM53|A0A0R1VM53_9LACO Transcriptional regulator ManR OS=Lactobacillus ghanensis DSM 18630 GN=FC89_GL002373 PE=4 SV=1 +-----GQNIFQGN-FKSYLDILNFlIGKANE-NGFIEKGFRESVLKREKLMSTYLSGKTALPHGNPSL---VKKSFLIALVLSKDTDWQGKMVNVVLL-LGIKSSDVSHSQKLMS------------------------------- +>tr|A0A1Y4W6X2|A0A1Y4W6X2_9LACO Uncharacterized protein OS=Lactobacillus gallinarum GN=B5E44_00580 PE=4 SV=1 +-----KHHISFFK-DEKLPTIIDQlLDFNDWDSDEQKNCYLNTVNNRESLQSTYLGNGIAIPHGDPKM---ITNSCIAVAILNRPLNWGNNKTDIICL-LMIADQDKKTIEPFMS------------------------------- +>tr|A0A099HVR5|A0A099HVR5_9CLOT Uncharacterized protein OS=Clostridium sp. NCR GN=KD33_05970 PE=4 SV=1 +-----NNNFYYKLQVKDKLELIELICNDMVKNDYITKVDKDSILKREALSSTEISNLVAVPHCISSENKNTI----AICTLKDAIKWGSASVKL--VFIAClnsEIKENK--HVFPFIHSSTKKSDIVNSLCECTSLNEFIEILM--- +>tr|B9Y3S8|B9Y3S8_9FIRM HTH domain protein OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_00458 PE=4 SV=1 +-----REELFFPaVEGKTKAEALDSLTASMVETGLISEAFATAIKEREAMSSTEITETVAIPHCFLSVPIDtML----AVGILKEPVMWGRSRVQL--LFIGIinpAVKKNK--CVFPMIYRLIQDPEKVQRLTRQTEADTFLRILF--- +>tr|A0A180CJR6|A0A180CJR6_LACRH Transcriptional antiterminator OS=Lactobacillus rhamnosus GN=PY66_05880 PE=4 SV=1 +-----AHLIFWKDKMADKQAALDFLVSQLEATGKVEPEFRSSIFRRERLGSTELDSGTALPHAVP---TSVRSLGVAFLILQKPIHWNSVPVSIVVLACVPEAQVKIYRDLVMDIYRLVQTKQMVQMIVGLHSTDQFLELI---- +>tr|A0A1Y3VCU9|A0A1Y3VCU9_9FIRM Uncharacterized protein OS=Faecalitalea cylindroides GN=B5G15_08855 PE=4 SV=1 +-----KELMFFKMKFDTKDQCLDFIIKKLESRNSVTAEFKQSVYQREKIGSPVLENGIAIPHGLP---TYVNEFTVVFVTLEKAIKWSDQYVDMVIMVVSPESETNAFEGLIMELYHISTNVEVLNGMKSIKNYEEYLSKI---- +>tr|K6Q7M8|K6Q7M8_LACCA BglG family transcriptional antiterminator / PTS system mannitol/fructose-specific IIA component OS=Lactobacillus casei 21/1 GN +------ELVQIIDTNMNWEKALRFSIKPLINEGIVTLHFEDVLVEQTkdQRSFAFFGTRMAIPHTVPE--NGALSEAFGFSIFKTPVSFPGNRS--ISIIVPISLRDtTKHLRAIHQLSHIAEDTSLIDKLINTNNSKTAYQLILE-- +>tr|A0A0F4LJA9|A0A0F4LJA9_9LACO PRD domain protein OS=Lactobacillus kimbladii GN=JF75_09950 PE=4 SV=1 +------NYIVLnKDTNIEWKVALHKAIMPLLKDKKIEKRYEFELQRQInnPDNYSFLGTSISIPHSLPK--TGILGSGIGFLVSKTPIEMPYNKT--VNIIAPVAFSHtDNKLKAINQFTSLAMNKNIINKILSCKTSFEVYQIILK-- +>tr|E7MLV5|E7MLV5_9FIRM PRD domain protein OS=Solobacterium moorei F0204 GN=HMPREF9430_00518 PE=4 SV=1 +------DWVQITDKELDWKDAIRYAFEPMRKVNAINNQYIEKTMQSFdtQLSYSFFGTEAAIPHADEK--TLIYEEFIGFTVFQKPIQFPNGNL--VHVIAPIAILNtSKHIYAVKKLAEIVMNEENIDWIIGFTNESALYQAFIE-- +>tr|A0A1L8UNZ7|A0A1L8UNZ7_9ENTE Uncharacterized protein OS=Enterococcus malodoratus GN=RV07_GL003122 PE=4 SV=1 +------EGIILvSTKQLTWQNAMELSCQPLLKEQVINQNYQTILMSQMadEEAYYFLNNRIAIPHSSPE--NGVIKGGCSLLISVDPIIFPGNRP--IHFISPFAIGKkENYLLAINQLLQLSKDEEYQQEILLCTTEDEVRKKIKN-- +>tr|A0A241RQJ1|A0A241RQJ1_LACPE Transcriptional antiterminator OS=Lactobacillus pentosus GN=CEW82_10045 PE=4 SV=1 +------DRISVHRDVESWRQALNQAGILLQNDHKVSRKYIDTVMQVTasPKNYSFLGLETAIPHASPE--DGVLADGFSLVVVQNGVDFPGHPG--IKLIVMLAIKDtSKHLRAIKQLNELIMNQVTFNELLSCNDSNSLYKVIEN-- +>tr|A0A0T1XGX7|A0A0T1XGX7_9RHIZ Uncharacterized protein OS=Rhizobium sp. Root482 GN=ASD31_22400 PE=4 SV=1 +---FLTMDISLSAIAPHKDAAIALAADRLAeTVDMAYGDARAALSGREALGSTALGKGVAMPHAVPWECPR---PALSLISLATPVEFDAPDHLRVDVVLALiwpRHRVGDFVRFSSLASRVVSDPAVLQAVRTSGAPGLIRSLLHA-- +>tr|S3I5A8|S3I5A8_9RHIZ PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN OS=Rhizobium grahamii CCGE 502 GN=RGCCGE502_29508 PE=4 SV=1 +---IIPEEIVINLPGGDRASALHHLATVLSrEVRVPTQTISSALLGRERMGSTAIGGGVAVPHALLTDIAE---PAKCLAILKHPIWFDAPDSEPVSVLLALlwpTSHENSYLPSLAGLMRRLRDPKLREALAAAQSVEEAALALSV-- +>tr|A0A1W6WBD5|A0A1W6WBD5_9FIRM Uncharacterized protein OS=Ruminococcaceae bacterium CPB6 GN=B6259_00850 PE=4 SV=1 +---LKPENIHFDVNPGhSKKSALKAISKLCGeHySTIKESALYKNFVGREKIESTGFGGGIAIPHAKIDNLTN---PFIAIVRFSKPVDWDSIDGKSVQVAIALvmpTVDTdNTHLEVLSHFSRKLADDEFLNRLLTEPDAVALYNYIIE-- +>tr|A0A246DPJ8|A0A246DPJ8_9RHIZ PTS lactose transporter subunit IIB OS=Rhizobium esperanzae GN=B5E41_23725 PE=4 SV=1 +---LPAENVSLDLVTKGKHSALSKIAAKIArRTALDPRMVLRAIWLRERLGSTAIGRGIAVPHAFVQPISS---PVTWFTRLAPPINFKSPDLDPVDLVFTIlwpRSKVHTFLPALSQLFRLVRVPLFREELRLARSPDEVIAILQG-- +>tr|F9NSB0|F9NSB0_9ACTN Phosphoenolpyruvate-dependent sugar PTS family porter, EIIA 2 OS=[Propionibacterium] namnetense SK182B-JCVI GN=HMPREF1162_0912 +---LSPDRFMAMPTGTGYWPATEALAAHLIDQGLADESFLATLRAREEEATMLLDGLVGFPHATIPgADRIILAMATIPR---------SPQQPGARVVFLMGVPDKTDyddtilVTVYDEIIRLTNDPDLLNRLSTLTNHEDVFWLMAS-- +>tr|A0A1R4GSU4|A0A1R4GSU4_CORGT Sorbitol operon transcription regulator OS=Corynebacterium glutamicum GN=FM102_14640 PE=4 SV=1 +---VSPEQFYVLPSLQSYEENLDAMLDNLVNRGLITADVQQGVKDREELRTTRLEGSVAFPHLSHPeIGDLVFAVGATKR---------EPEDSDVRLIFLLLLPEDVGgyddllVQLYDEIIRMAADQEQVKKVSSSTSFHDYLLHFLR-- +>tr|A0A1Y4AZ34|A0A1Y4AZ34_9FIRM Uncharacterized protein OS=Eubacterium sp. An3 GN=B5F87_09205 PE=4 SV=1 +---VEPEMLFLLPVDCTFREALDHMLDRLLEEGIIDEAFREAMLEREAKVTMLFDENIGFPHILYEGKKLIFALGVTGR---------DKAENGLKLVFFLGLPKNMDyddqilMKIYDEIISIAGNGQIMQGICECRSAKEFYSYMIK-- +>tr|E0RRQ9|E0RRQ9_SPITD Uncharacterized protein OS=Spirochaeta thermophila (strain ATCC 49972 / DSM 6192 / RI 19.B1) GN=STHERM_c22360 PE=4 SV=1 +---LKPEGIFLNMKAYKKKEElfkilVRRACEvGLVPGEMEEP-VLNELLAREAQSTTGIGEGIAIPHCKMEGLPHA---VIIAATIPEGMKYGSVDGKPVRLLFSFlfpADQGTQYLQVLAKLSRILKEEALRNRLILSSSPEEFRDILAQ-- +>tr|A0A166MZC7|A0A166MZC7_STAPS Putative transcriptional antiterminator, BglG family / PTS system, mannitol/fructose-specific IIA component OS=Staphylococcus p +------EFLGSIHQKMSRNEAIAEVMRPLEQAGMIHAQYKKEIINKlDEFGAYmVISPHIALLHGSTEFA--LKGVGMTLFHFEQGVYFGHERFDPVKVMIGLATDEPqKHLTALKELSDILMDDTMRVQLLNG-------------- +>tr|A0A0Q1AAI0|A0A0Q1AAI0_9DELT Uncharacterized protein OS=Desulfuromonas sp. SDB GN=APR63_03095 PE=4 SV=1 +------EHLMFNMNFEHKQHLFEYLCKKAEQDGFITSweKMYKAVAEREQQGITELKSSVVLPHARGDF---ITRLFTYFVVNPQGISYQGIKGDKAKLVIFIgiPPQDKDYLKLLAAISRILSKPGFFDQLLRAEVIEDAVYTF---- +>tr|A0A1G3KIQ0|A0A1G3KIQ0_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWB1_27_13 GN=A2Z98_02530 PE=4 SV=1 +------DLIFINPPVKTKEELFDFLAKKAFKKGLVENaeDFEYGLIDREAQGTTELKPGISIPHAKLDV---VKEPFIIICTFKKPIKFSPGFGRGVEVVFLIgsPKLDNTYINILASVARLMDKDDFIKEVKDANVSEDVIHSI---- +>tr|A4A2C5|A4A2C5_9PLAN Probable PTS system, fructose-specific IIABC component OS=Blastopirellula marina DSM 3645 GN=DSM3645_25694 PE=4 SV=1 +-----PETIKTPLMGKSPRKIISELCELAAEAQLLwdPAKMSDAVLTRENMHTTALDNGVALLHPRRPLPDIISEGFLCLGRTYQGVPFGGSRGILTDVFFLIASVDdRSHLRTLARLSRVISDSAFYTKLRDAADPIATIEMIA--- +>tr|A0A1G0L1L0|A0A1G0L1L0_9BACT Uncharacterized protein OS=Gemmatimonadetes bacterium GWC2_71_9 GN=A2083_04400 PE=4 SV=1 +-----EENALIAVPAGAVSDVVQALVSRVTFP-ERvdADLVVQRVVEREALCSTASPEGVALLHTARWEPRVLAaHDLLAVGRLSEPIDFGALDGGRTDMLFLILARNeRDQLVLLAKVARLCREPVFVDGLREASAAAEVVALVE--- +>tr|S4DKD4|S4DKD4_ENTFL PRD domain protein OS=Enterococcus faecalis 13-SD-W-01 GN=D920_00946 PE=4 SV=1 +---------HVHLKAETQKEVLEKMVRNAENKGLVTSSYLETVLVRENKGSTRIGKSIALPHGDMNE---IRHSFISIATLEKPVLWYTDE---VQMVILLGLKKQElgnpETKKFFSMIHYLiENQEVFQKVIKEKDKLNVLKLLS--- +>tr|A0A1I0GH96|A0A1I0GH96_9FIRM Lichenan operon transcriptional antiterminator OS=[Clostridium] sphenoides JCM 1415 GN=SAMN02745906_1190 PE=4 SV=1 +--------CFGYISAENRFQAIKELGAMLERKKGIGSQMINAIEKRERISSTEVGNLVAVPHVLMQGEFSS-CIAIGILDN--PVQWGSEMVQMVFLAC-FNQSGNQYARIFRTLYKVVHSEELVRRLIQADDFYTFQNIMCGR- +>tr|A0A1I5C7Z8|A0A1I5C7Z8_9CLOT Transcriptional antiterminator, BglG family OS=Proteiniclasticum ruminis GN=SAMN04488695_10610 PE=4 SV=1 +--------NFNIISASSKEEIINIMGLKLIKNGFTNERVIEEVLDREKMASTDIGNLVAIPHTLSSYQDKS-FISVGLLES--PVYWTKENVQLVFLVC-FNREDRENLDIFKYLYNFIKDEGAVKSMIRFSNFESFMKILKNV- +>tr|S0KTL2|S0KTL2_ENTAV Uncharacterized protein OS=Enterococcus avium ATCC 14025 GN=OMU_01378 PE=4 SV=1 +-----PELVFLREQVENKEECLNFMIEKYQALGIAKEKFGESVWVREKLGDTSFSVSVAIPHADPS---EVNQTSIGIMTLAKKISWGINNV---NVILFFAISDTDIDvakSKITGLLEFIEKEENVEQLIQVTDKETLLELVMGE- +>tr|A0A1V5WNF5|A0A1V5WNF5_9SPIR Heat-responsive suppressor HrsA OS=Spirochaetes bacterium ADurb.Bin215 GN=hrsA PE=4 SV=1 +---------------------------------------LDGLLSREELSSTAIGHECAVPHIH---SDLVSETGIVIAVLDRSLDFGEELPvRIVCLLAGPVGETNQHLQLLSRVCQFLYDDEFRARMIACTTVDELRDLVQKR- +>tr|W1Q4X2|W1Q4X2_ABIDE PRD domain protein OS=Abiotrophia defectiva ATCC 49176 GN=GCWU000182_000569 PE=4 SV=1 +---LIKTPDQVQLTANNQDQALELVLAQASPQNLANPAFVQSVYEREQMGATSVYTGVALPHSDPK---TVTHSEIVLVSLAKPVSWGQN---QVKLIFLIAVAERDMKLfkeSLVALYALIEDQELMNQLSQCQDGASLKARLL--- +>tr|G5K9N0|G5K9N0_9STRE Phosphoenolpyruvate-dependent sugar PTS family porter, EIIA 2 OS=Streptococcus pseudoporcinus LQ 940-04 GN=STRPS_0774 PE=4 SV=1 +---LIGQRIYLHQDCQSLEECIAYLVEDKDTNCNYSSAYRESIMQRESLGSTSVYTGIALPHASPD---TVEVSQLSLLTLKNPIQWGAN---QVRVVMLIAIKGGEEEVykdALIHIYSKIDNQNFIRKLANAKTKDDFMCVLL--- +>tr|I9AR93|I9AR93_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Pelosinus fermentans B4 GN=FB4_1161 PE=4 SV=1 +--------------PLDWRLAVETVGRLLYQKGHIEKEYIHTMICNIEKYGPYiiVGKGVALAHAKPN--ETVLSEGLSLLVAPKGIKMDPDEKKTVYLLFAFCTQGGFDyIELFNQIASIGRNPALFSKCIQAKKTDDIYHLL---- +>tr|A0A1L4FSR9|A0A1L4FSR9_9MOLU PTS sugar transporter subunit IIA OS=Mycoplasma pullorum GN=BLA55_03355 PE=4 SV=1 +-------------DKLDWVEVINKGVEILVENGYAKQTLADAILEStKQFGAYYvLERGLALLHAAP--GDYALKNGTSVMILDDFVRFNNQEDKEARIIVTLSAVDsSSHLNILQEFSHYFMNDEFKKEILQVKNIEEFWNLIDK-- +>tr|X8HNR5|X8HNR5_9ACTN Phosphoenolpyruvate-dependent sugar PTS family porter, EIIA 2 component OS=Olsenella uli MSTE5 GN=HMPREF1503_0782 PE=4 SV=1 +--------------ILDKVTAIEMLSGRLMELGIVSEAFPASVMAREEAASACFNGLFALPHATVMDAHRT---VVCTLISDAGVDWDGA---VIHLVMMIAVCDTDrsqFSVIFNDLARHLMDKESLYRLTDSTTAEEFRQMLC--- +>tr|A0A0G3EGT4|A0A0G3EGT4_9BACT EIIBCA-Man OS=Kiritimatiella glycovorans GN=manP PE=4 SV=1 +------------LGGGTPEEVLGQMCRCMEEQGFIENsdALLEQAMQREAISTTAMEHGIAFPHVrGVEGGGLTLAAGVH----RKGIHFDPDSRRLSRIFLFMTiptAASAFYLRLVSGLSESLSRKEVREEVLGAETPQELWKRL---- +>tr|A0A1G0ZRD6|A0A1G0ZRD6_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_50_93 GN=A2X45_20610 PE=4 SV=1 +------------IKAKSKEEVIEIIGHHSAKAGFVTDgaAFVKALIKRESLITTAVGSGIVFPHArDIKACGLTLAVGTV----KPGIKENGD---SLSIFFVSAvpmQTSIFYIELISKLANYFSKAENRKKILDCTKPEEMWKIM---- +>tr|A0A1B9JZ54|A0A1B9JZ54_9GAMM Uncharacterized protein OS=Gilliamella apicola GN=A9G12_08535 PE=4 SV=1 +---------------SQKSSIINLMATK--SEPYLSdvNKFFADVMTHEQEMETDVVPDIALPHAKS---SAVKTPFIAVAKNMNGVVWNN--SNKVKLIVLIGAPehaNKEHLTIIAKLASNLAMDEFVEDLLNS-------------- +>tr|A0A1F9AGS0|A0A1F9AGS0_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RBG_13_61_14 GN=A2V67_17035 PE=4 SV=1 +--YLVPERVWIKVEVANRNDLLAYLARQTAGCALVPdeQEFFKLLIHREEEMSTGVGRGLAVPHADPP---AMKSTFLAAATLASPIDYQSFDRVSVDVVFMIFGCPddtSLHLRLLARISRIARLPGFLDRLRQVQTTPDFLRVVEEA- +>tr|A0A1M6NPT6|A0A1M6NPT6_9DELT PTS IIA-like nitrogen-regulatory protein PtsN OS=Desulfatibacillum alkenivorans DSM 16219 GN=SAMN02745216_02655 PE=4 SV=1 +--YMSPEQVYLDAPIRGKEEILHFVSQAFAQCGAAPdkRTVYDCMKEREDIMSTGIGGGVGIPHAACA---GVTRPAVVIARLARPVDFQALDAHPVDVIIAMVVPNarvSLHLRLLAAISRLVKSTNFLDDVRSASSSGDLFSHIKEI- +>tr|G8QTU4|G8QTU4_SPHPG Phosphotransferase system mannitol/fructose-specifc IIA component (Ntr-type) OS=Sphaerochaeta pleomorpha (strain ATCC BAA-1885 +-DLLDKQCILLDMDCQDLQQILKSLLTTISEAHPQQapAPMMEKVLTNPGFSTVCMGFGCAISHARCT---EMKKTFIAVARLSPPLDLGADDKLPVALFFLLVGPQsspLFHIKILSRIARLLHASEFRKGLLQAKTSEDFHQLICNK- +>tr|A0A1G3RPQ5|A0A1G3RPQ5_9SPIR Uncharacterized protein OS=Spirochaetes bacterium RIFOXYC1_FULL_54_7 GN=A3J97_06000 PE=4 SV=1 +-SILDPACVVVDLDLRSKEEIIKALVDLLSAGGDVTnrDGLLHDVMAREALAPTGLGMSCAIPHAHSA---SVLCTAVAAARLKFPVDFGAPDGTPATLVFLMVGPKdaaGMHLKLLSKFARFLHDDAFRDAVMTTADASSFAELIYTR- +>tr|A0A1X2TGC1|A0A1X2TGC1_SALCE Phosphoenolpyruvate--protein phosphotransferase OS=Salmonella enterica subsp. arizonae serovar 50:r:z GN=R530_00730 PE=4 SV=1 +--LLALENIFVGEPLSNKEQVIQFLCGNLGVNGRTEhpFELEEDVWQREEIVTTAVGFGVAIPHTKS---QWIRHSSISIARLAQPVDWQSEMG-DVELVIMLTLGadeGINHVKVFSQLARKLVNKNFRQSLFAANDADSILALLEA-- +>tr|A0A1V3XFQ4|A0A1V3XFQ4_9SPHI Phosphoenolpyruvate--protein phosphotransferase OS=Pedobacter himalayensis GN=GY25_03695 PE=3 SV=1 +--LLALETIVVNEPLTSKEQVLQFLCGNLAIHGRTEnpLELEEDLWQREEIVTTAVGFGVAIPHTKS---QWIRHSSISIARLDKAIDWESDLG-DVELVIMLTLGaqeGINHVKVFSQLARKLVNKTFRESLFAATTPQSILDLLNA-- +>tr|A0A1S1XER9|A0A1S1XER9_9NEIS Phosphoenolpyruvate--protein phosphotransferase OS=Chromobacterium amazonense GN=BI343_00610 PE=3 SV=1 +--MLTAECLLPSVAWRSKAAALKGLVDRLWLLERCDdrYGMEEDLWLREQAYSTGLGHGFAIPHAKS---KHVLHPTLCLAKLEQPVDWGASDGQPVDMVLLIAFNasdaGAEHLKFFSRLARLVMHEDFRRQLREASDPQGLLTLLQS-- +>tr|A0A1Y6MFN4|A0A1Y6MFN4_9GAMM Phosphoenolpyruvate-protein phosphotransferase OS=Photobacterium sp. CECT 9192 GN=ptsI_2 PE=3 SV=1 +--ILVKQCVFKGADFANKEQVIQALVGNLGIQGRTDdaYKLEEDVWAREAVFSTGLGHGFAIPHTKS---DHIRHSSISIAHLDKPVDWMSDSG-EVDFVIMLTLNkdqGDQHMRIFAGLARKLIHESFRDSLRQAESPEAIIAIITE-- +>tr|A0A1T4LZ68|A0A1T4LZ68_9ENTE PTS system, galactitol-specific IIA component OS=Pilibacter termitis GN=SAMN02745116_00870 PE=4 SV=1 +--YIQPSLVFLGEEFEQSDNVFDYVHNQARKDGFVEEIFLEKIKAREVEFPTGIqleKIGVAIPHTDAE---CIREEFISVLTVPEGVSFARMDLPtsnvEAKIIFVLGLKePHAQLSMLQSLISILRQTEEIEKLQTQKEVQAFIEQIKEI- +>tr|A0A239W661|A0A239W661_LISWE Mannitol-specific phosphotransferase enzyme IIA component OS=Listeria welshimeri GN=mtlF PE=4 SV=1 +--FLKKGMVWVQSDIEKQEDLFQMVAESGKSEGYVTDDFLTRLTDREQTFPTGLkldGYGVALPHTDPE---CVTEQFIAVITVkDGGIPFKLMEDAgqtvEANLIFVLGLNePHSQLAVLQQLMGTIQDKDNVAALLRAKDEDEVKQILETI- +>tr|A0A157SD23|A0A157SD23_9BORD Nitrogen regulatory IIA protein OS=Bordetella ansorpii GN=ptsN_1 PE=4 SV=1 +--LLKDQDVLIDLDVPDKDALFDVASQGLANGCQISaQNILAALTRRERLGPTALGQEVAVPHASVE---GLDGIHVLYARLKQPCFFDGATGMPVMHALFLIVPMpanQTHLDMLAEVARLFSQPDFQKALRRAESPAGIRQAFQAY- +>tr|A0A0F9SWN9|A0A0F9SWN9_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0402010 PE=4 SV=1 +--YLTPERVVVLKSVTKADALGELVDVLVATDGGVSaEELIKEVWKREDLMSTGIGNGLAIPHVRMS---GIRLAAMVVGVsRAGIDDYESLDKKPVHIIVLIAAPEgahETYIRMLAKVADVLKEDTLRQAAIEADEPATIHRILTEG- +>tr|A0A161QJF2|A0A161QJF2_9BACT Uncharacterized protein OS=candidate division Hyd24-12 bacterium Dam_1 GN=AO394_04560 PE=4 SV=1 +--MNKSCYCVWNLQS-tDRESALSELLSSVPGIGS-HsrEMLLKALQIREQAGATLVTTGIAMPHCRS---ILVDDMVIAIGKSDSG-iPWPEEPAR-VVVMFISPVKlsgPQEHMNLIAHLANQMKTN-GPEKITGADSPERLAGLLGL-- +>tr|A0A1V6FFL8|A0A1V6FFL8_9BACT PTS system fructose-specific EIIABC component OS=Lentisphaerae bacterium ADurb.Bin082 GN=fruA_3 PE=4 SV=1 +--LLPKEHVLFGLPLNiSRRELLRMLSEPLAKDGAIDdiEVFLDAVERREAEMSTQMNGGTVFPHASS---ATVQCLAITVGMAPEPGfPFDPDADEKGRVFFLIAIPaaaPAAHLPLLTHLAGFITAKGKLEKLLQADSAAAVHKMLLA-- +>tr|A0A1V5KRA7|A0A1V5KRA7_9BACT Heat-responsive suppressor HrsA OS=Verrucomicrobia bacterium ADurb.Bin474 GN=hrsA PE=4 SV=1 +---MRPDHVLCPLIA-sNAQDAIQILMDGMKGLPAIThsEDFLKEVFLREKESSTHIGHGVAIPHARS---RNVSGMVLAAGRLDQEIl-WDS-SGKPVRIVLLMGIPpqsIETYLSVMKAFAHGFRKQNLASRILQAPDTNALSQILSS-- +>tr|B0VG30|B0VG30_CLOAI Uncharacterized protein OS=Cloacimonas acidaminovorans (strain Evry) GN=CLOAM0343 PE=4 SV=1 +--YMRPENIFLDFTAENKYDAIRILSEKAKELKLVRDarWLYEVVVAREELVSTAIGNGVALLHPRHLHPSKIKAPSILFGRSSEPVDFDAPDNKPVNIFFMLLLHNdKQHLFSLSYISRLVMNQDILKGLTEAKDAQEIHQLLTV-- +>tr|A0A1V6DHB9|A0A1V6DHB9_9BACT Nitrogen regulatory protein OS=Candidatus Cloacimonetes bacterium ADurb.Bin117 GN=ptsN PE=4 SV=1 +--YMRPENIFLDFEAENKFDAIRILSVKAKELKLVRDarWLYEVVVAREELISTAIGHGVALLHPRHLHPSKIKTPSILFGRSSIPVDFDAPDNKPVNIFFMLLLHNdKQHLFSLSYISKLIMNPEILAAFSTASSVEEIHNCLTV-- +>tr|A0FL35|A0FL35_LACPA Putative PTS fructose-specific IIBC component (Fragment) OS=Lactobacillus paracasei PE=4 SV=1 +---IDIKNIDTSIEPMTKDQAIARMINKLKLNGYVQdaDTFSKAIYQRENEISTAVGYGVAIPHART---SAVKKSTISVFRDLSGIPWGQE---KVNLVFMIAAEedaSDEHLKMLSKISTFLMDESFRAKLITAADPNEMYEILVQE- +>tr|A0A0R2XK30|A0A0R2XK30_9BACT Uncharacterized protein OS=Verrucomicrobia subdivision 6 bacterium BACL9 MAG-120924-bin69 GN=ABS33_00960 PE=4 SV=1 +-DLINEKNLIPNLVAKDRSLAYSSMLQVLLNNGFIKEdittSCLEGLKAREAKMTTAMGGGFALPHATIP---KLAKPCYLLARCPEGVECEAVDGKLVTLFFLILTPPdhsQEHLQTLATVAKFFNRRGIKSKILQAAGIPEILSIIRP-- +>tr|A0A1T4WNZ9|A0A1T4WNZ9_9FIRM Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Gemmiger formicilis GN=SAMN02745178_00883 PE=4 SV +-ELMNPKGVLLYAKIDNSADALGILVELQEGIGVITNgnAYYNAVSYrETFGGTTAIGGGIALPHACNA---GVSAPGISALLLRRGVDWGAPDGEPVDLVFMIAVPPgseSLHLQILARLVNLLSRSDLVESLRTASNPHRFVELIAK-- +>tr|A0A0S7WK56|A0A0S7WK56_9BACT Uncharacterized protein OS=candidate division TA06 bacterium DG_26 GN=AMJ40_02565 PE=4 SV=1 +--LLSPETIAFPLHASRKESIIEELVGLAVAGGAIShkKEVVQRVKEREEILSTTVGKGVFIPRVRSR---HVSRICLCLGITRKALDLGALDGNHVRLCVFLGIPEgkiEAQVKYLVRIFRLFNQDSFRSALLKAADKKDVIEIVRSE- +>tr|H6SR97|H6SR97_PARPM PTS IIA-like nitrogen-regulatory protein PtsN OS=Pararhodospirillum photometricum DSM 122 GN=RSPPHO_03193 PE=4 SV=1 +--LITPDSILPALRVSSKKQALQELAKRAAELtEQHERAIFDVLLERERLGTTGVGNGIAIPHGKLPT---LTGLHGLFARLVEPIDFDSIDDQPVDLIFLLLAPEsagADHLKALARVSRLLRDRATCEKLRGANSAEALYTLLSQ-- +>tr|A0A0R1SY26|A0A0R1SY26_9LACO PTS system fructose-like transporter subunit EIIC OS=Lactobacillus saerimneri DSM 16049 GN=FC54_GL001656 PE=4 SV=1 +--KNIAIKTVFDIAALSKKEVLTEVTTSLFNDGIISdqAGFLHDLCYRENELSTYIGHSIGLPHTRS---KYVKRPVILVGRLSHNISWDQDHS--VNFLVLIAVpEtatGSLHLRILAHLSGLLIHDDFREKFVNASPVEAHKMLT---- +>tr|A0A0M4JIP4|A0A0M4JIP4_9MOLU PTS system, fructose-specific IIB component OS=Spiroplasma cantharicola GN=fruA PE=4 SV=1 +--IYKEKNIFLNIDLNSKDEVLKYICNKANELGIYQdtKSLLKAFYDREKQGTTGFEDGFAIPHAKV---KGITSASIICIRTLNGIEWEALDGQPSNVIIALIIPEnasKEHLDILSQTAKKLMDDKLRQKLKDAKDSKEFSKLIQVK- +>tr|A0A0K1P740|A0A0K1P740_9MOLU PTS system fructose-specific IIABC component OS=Spiroplasma turonicum GN=fruA1 PE=4 SV=1 +--SEKNLLVFINKDFSSKEDILKFISEKSSEANFIKdaDYVYKKFIERENLSSTGLQDGFAIPHIVV---EGLIEPYIICIKNNRGVFWDSLDGKNTSFIISIILPKndkSEEKDIISEITKKLYNKSFKEAIKKSQLTSQIEELLFLK- +>tr|A0A222EPW9|A0A222EPW9_9MOLU PTS system, fructose-specific IIB component OS=Spiroplasma corruscae GN=fruA PE=4 SV=1 +--NKENVLIYVNKDFKSIENLFIFISQKLYTSVGLKerNDYIN-FKSVYDDSIIAySKDNFILKKCAI---PEIKDTFIICVKNNRLIKTDKFEKTK-NFFIFVLHPIkenFISNIIFDELLKKLKNKEFRDIIKTIGLTFEIENLLISK- +>tr|A0A1T4JFQ6|A0A1T4JFQ6_ENTFC Probable PTS system regulatory protein OS=Enterococcus faecium GN=FM130_11815 PE=4 SV=1 +--LISSNVYF--DHLDSKEAAIRFLVdQQQFENEDLKQRFLHSIFEREEIQSTYLENGFAIPHGNPN---VVKQTSVAVLIADKPFSWGYQ---KADIVVLLMIREEdvkEVEPVMKMVMQGIEDKNWfISKMLEVRE------------ +>tr|A0A233IRT6|A0A233IRT6_9FIRM Uncharacterized protein OS=Paraclostridium benzoelyticum GN=AVM15_11755 PE=4 SV=1 +--IFSQDLFFIDLDFDNKYDVISYMSDKLLENNYIDEEMKNSYIEREKIATTEIGNMVAIPHGAHG---KVFKNAIAIGILKSSMNWEVG---QVRLVVMLSLQKEsilNYEDLFSNIYKRIDSIAKvISIC-ESKRYEKFISMFK--- +>tr|A0A1V6AQC1|A0A1V6AQC1_9BACT PTS system fructose-specific EIIABC component OS=Candidatus Aminicenantes bacterium ADurb.Bin147 GN=fruA_4 PE=4 SV=1 +--YFKINQLVFELRASEKVAAVEELIDVLAKQKLVRnrKMILTRLMDRETLESTALGDGIAVPHARVDS---DGEIVIAVGRSSEGIDFSAPDKKKVHLIILIIWNPtlpGLFNHLFAGLAHFLRDPHFRRRIFEAKDKNALWEALGEI- +>tr|C6JPX1|C6JPX1_FUSVA Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Fusobacterium varium ATCC 27725 GN=FVAG_01021 PE=4 SV= +----EKKYIFRLNEKLTRDEVLETVGNKFYHDGIVTTGFVKAIQQREKDFPTGMilekGTNIAISHTDD---KYVIKDRIAIIIADNPVIFKSIENGkndiKCNIFFVMALTKeNKN-EILSAMADLFENYEDILKKFPLMTDEEILDIL---- +>tr|A0A0R2LJR0|A0A0R2LJR0_9LACO PTS system fructose-specific transporter subunit IIABC OS=Lactobacillus kimchiensis GN=IV57_GL001790 PE=4 SV=1 +--VLDPKDIVLDVKAASKNELLKYLANLVSNSntTVNTEEIYGKYLVREKNCPTDLGSGIALPHVQV---ESITKLTMLVVKLQRSIKWSKSE--SVDIVISFLVPEtdknYQYIPYLASVARLLLRPSFVQSLRQTKNKFAIVKLF---- +>tr|A0A0R1K3Y5|A0A0R1K3Y5_9LACO Uncharacterized protein OS=Lactobacillus alimentarius DSM 20249 GN=FC67_GL001714 PE=4 SV=1 +--ILDVKNIVMEVDLHSQAEVLKYLTDFYHRLnlATDSEKLYGRFLLREKESATNLGSGIVMPHAVD---SSVQKLTMIILKLENPLMWDDQ---KVSWVIALLIPEsekdFSHVKYMAGIARLLLKPTFVYALKETTTAKQVEKLF---- +>tr|A0A1A0EA54|A0A1A0EA54_RAOPL Uncharacterized protein OS=Raoultella planticola GN=AYO04_16555 PE=3 SV=1 +--LIVPEMIQWELDVTDKNEVIKKMVDNLWLHrrTDARDKLYQDIWARENPFPTVVGSGFAIPHART---SAVHVSTISVARLVNPVTWGGV---QVDTVFMLSISesgaENDHMRYFSTLARILMNDEFVSKAKATTTPDELYNLIFS-- +>tr|D7VFB9|D7VFB9_LACPN Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Lactobacillus plantarum subsp. plantarum ATCC 14917 = +--LINKNTIQFaTASHLDWQQAIALATLPLLSSGNVEQSYIDAMIRNVYSNGPYinIGDRIAFAHARPE--EGVNKLGMALLCLDEPIELLDNQ-HRIQLIFVLAASNdRSHLKALAELASMLGDKNRLKQLLDARKVSEVESVIAEG- +>tr|A0A1Q2D4H8|A0A1Q2D4H8_9ENTE Uncharacterized protein OS=Vagococcus penaei GN=BW732_02875 PE=4 SV=1 +---VNQDHVFLKQNLKTKEEVFKFLATTFSQKELSYSDISSELNKRELLGYTSLNTGIAIPHVPP---YLVKVSTVMFITLKKPISWGYNK---VSLILFLAIKEEdvfYAKNIIEEIQEVIESSKQIETISASSSFEEFKKKLLR-- +>tr|A0A1V4DG94|A0A1V4DG94_9ENTE Uncharacterized protein OS=Vagococcus sp. D7T301 GN=BW731_04670 PE=4 SV=1 +---SDNQYVYLRKNFDNKEEILTFLSNELENADKVTNSFRETLFQREINGSTEMDIGVAFPHADP---RTVKETKIVFLTLAKPIKWNMLD---IQIVCLVLISEDdmgQAKNIIATLYDLFKNQKKLNQLIESKCKKEFKDCLTK-- +>tr|A0A0L8EWQ4|A0A0L8EWQ4_9CLOT Uncharacterized protein OS=Clostridium sp. DMHC 10 GN=AGR56_17770 PE=4 SV=1 +-DIFDEKLCFLNSEFTDFKEAIYHYGSIMEEMGYAKKGFCKSILEREEKGSTYVGKGIAIPHGES---VYVNQSKVCIVKFKEPISWEDND---LEFIIILCLNfeNiSTTKNFFKNFYTVLESDKTMLDIKNAKSAEEIINAFK--- +>tr|C4V3X4|C4V3X4_9FIRM Putative licABCH operon regulator OS=Selenomonas flueggei ATCC 43531 GN=HMPREF0908_1218 PE=4 SV=1 +---FRPEGFYVDQLFHTRDECLNFLTDEAVRNGWMDAEGKSSVFEREHMSSTAIGDFVAIPHALL---TEHMISNISVLILKEPVQWEDF---PVRVVFLLNIEQSkasLWEKMFLKLYSFIKEYHGLESLLKHKSYEQFMEDFIA-- +>tr|A0A174B9F1|A0A174B9F1_9CLOT Putative licABCH operon regulator OS=Clostridium disporicum GN=licR3 PE=4 SV=1 +---FKESLFFNHLDVDTRDEALENITSKLIDEGYITQCVKENIFKREDLASTEIGELVAIPHDMN---EEIKQSFISVSVFNKAITWDKE---KVQVVFFIGMSTVdkeEWKSYLEQIYKNIIDGEIIRKIIKCQNFEELKMLVSK-- +>tr|A0A1G4A1A1|A0A1G4A1A1_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium GWF2_62_7 GN=A2107_14510 PE=4 SV=1 +--MTQPAFIAPGLTAKSKASIIRDMVALAVSTGRVYdpHALIASVEEREALCPTAFPGGLALLHSRYQQPAFSEEPFIVLGRALQPIHFGSPDGRPTDLFFLVCCQDvKLHLHTLARICLMAQKSALLALLREADDATSMYDCLVN-- +>tr|A0A1G0YFS1|A0A1G0YFS1_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_57_35 GN=A2X46_16800 PE=4 SV=1 +--LFKPELIAPAMTSRTKASVLRDMVKLAESSGLVNypQELVRSIEERERMCSTALAGGMAILHPRNHEPYMFGDSFVALGKSIQPVPFGSPDGATTDVLFLVCCQDdRIHLHVLARVCMMCQQTSLLLELREAQDAAQMYDLLVK-- +>tr|A0A1V6FEH3|A0A1V6FEH3_9BACT Nitrogen regulatory protein OS=Lentisphaerae bacterium ADurb.Bin082 GN=ptsN PE=4 SV=1 +--LCRQEFMHPSLPGQSRSAILKALTELAETTGLLYdpKDLYERLRQREEEYSTAMSGGIAMPHPLVRDDFLFETPFVCIAKTPRPVFFGQaDDGQGTDLFFLICCLEsQQHLQTLGRVSLLCSRTSLPDDLRAAETSAEMYEALQN-- +>tr|F9QEM2|F9QEM2_9MOLU PTS system protein, fructose-specific family, iiabc component OS=Mycoplasma anatis 1340 GN=GIG_00491 PE=4 SV=1 +--LLNPKSIFINIDVNDHNDALEMIAKKLYEANFIEdkTRFLNALNYRENLMSTALNDGIAIPHGIS---STVIQPTISLAILKNGIDWKAEDNKKVNLIFTIVLSKedrEIQLDSIQVIADYSLDDNFHSEIMNAKTQEQAYEILVK-- +>tr|C4XF07|C4XF07_MYCFP Uncharacterized protein OS=Mycoplasma fermentans (strain ATCC 19989 / NBRC 14854 / NCTC 10117 / PG18) GN=MBIO_0464 PE=4 SV=1 +--FLNKNSIFVHSNFDKKDDVLHFLSHQLNEQNFVSdeKKIYEAFLYREELMNTAIGGGIAICQALS---STVKKDTLCILTMNndGVNDWKADDEKNVNLVFALVLSKnnrNLQIDTLQMISILALDNTLDNKIMKAKNADEIYEVMSK-- +>tr|C0CZN4|C0CZN4_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 (Fragment) OS=[Clostridium asparagiforme] DSM 15981 GN=CLOSTASPAR_02461 PE=4 SV=1 +--LLDEDLIVLDYQGRDKDQVLRFMAEGLEQKGYVTEQFLEDVMARESRGSTALGFGVAIPHGVS---GYVNRPAVSVVRLEESMDWAG---EPVSLIFMLALNfkDiESTRAFFNGFYHLTCEVKIVELLRGVTSPGELIRVISEN- +>tr|R5EG99|R5EG99_9GAMM Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Succinatimonas sp. CAG:777 GN=BN779_00465 PE=4 SV=1 +--AIDEHCVIYKLKANTLDEVIQVLTDRLFEVKAIKskHDLLKGINEKIAKNPAGIAHGIAIPHTRG---NYVNRSSLAVATLKTPLNCGASDNKPCDLFFLIAVPDdgVSHINLLSNLSLMLSEPGFADKLRHSGSNEEITKRL---- +>tr|A0A1C6E1H8|A0A1C6E1H8_9FIRM Probable licABCH operon regulator OS=uncultured Eubacterium sp. GN=licR_6 PE=4 SV=1 +--LFSPEFIFTDLEVKTKEECLKIMSQAMEEKHVVTEDFYDSVMDRESKTTTTIGNGVSLPHGSP---TAVNESKVGIAILKNPIMWDNE---QVQVVFLLAFRlstRDeiSRIQMFyKEYVTLIDSEEKLEKLKSMKSNIELYKYLI--- +>tr|C6B6T4|C6B6T4_RHILS Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Rhizobium leguminosarum bv. trifolii (strain WSM1325) GN=Rleg_6753 PE +--IIRPEHTFIGVSAPTKWRALQTIADKAAKAfSVDGQTILKALEAREKLGSTGIGNGIAIPHAAID---GMTSPRGLLLRFAHPLDFEAIDDIPTDIAFVLLFGennRGEYLNVLSAIARRLQSDGTLVAMRKARTVDEYYSDFIA-- +>tr|A0A1F5EXG5|A0A1F5EXG5_9BACT Uncharacterized protein OS=Candidatus Coatesbacteria bacterium RBG_13_66_14 GN=A2Y64_09070 PE=4 SV=1 +--LIPAGAINLDLTATKSHEALHEMAHLVVGQPGLPsnAEVISAIFNREMEYEAAVGSGAAIPHIMMA---GPEKPILAVGRSTNGIKFGRNGKEKVKLLFLLISPAenpHLHLHTISRIAKLLHRPEVRESL----------------- +>tr|A0A0A1MW87|A0A0A1MW87_9BACI PTS system fructose-specific EIIABC component OS=Oceanobacillus oncorhynchi GN=fruA_4 PE=4 SV=1 +-DLLKKDVMILNLQGTSKEAVIDEMISSLYKNGIITeqASFKEAILAREDQSSTGLGDGIAMPHAKTA---AVTEPTVLFAKSEAGIDYDSLDGQPAHLFFMIAVPDdgsDTHLQTIAALSRLLMEPDFTGELKEAGTPDEVQALFAE-- +>tr|A0A1V5YYL7|A0A1V5YYL7_9BACT PTS system fructose-specific EIIABC component OS=Candidatus Hydrogenedentes bacterium ADurb.Bin170 GN=fruA_1 PE=4 SV=1 +--YLSADCVLPEVQTKIKADALKELTDLLIKNRKLKglEAALDQIMARESTESTGIGNGIAIPHARI---SGLKSLYCAMGRFKNGIDFSAVDRKPVYLVFAIFYPPtqqTTYLNFIATLVKMFKNKSHQEIIMKADSAADVFAALKE-- +>tr|H1B4G2|H1B4G2_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium 6_1_45 GN=HMPREF0981_00095 PE=4 SV=1 +--LFDPKLFFV-KDFTEKEEIQKCLVDAA--SvLYQLDNLAEEIELREEFGSTYFGNGIAILHPMHLL---TDDSFIGEIILKKPAVWDTE-GNHVNLIFLVCIQKnnLEAFRAWDYLSPLLFNNEFKQEILSVEDYGDFKRICEE-- +>tr|R2TCV4|R2TCV4_9ENTE Uncharacterized protein OS=Enterococcus pallens ATCC BAA-351 GN=UAU_00709 PE=4 SV=1 +--LFNEKLFYH-GRFSEKKEVLDKICSISVTKvGDKVFQLREAVELREGLGSSYFGNGIALPHPINPI---MAETFVSVILLKDELNWDTD-GNKVRLVMLVAIEKnnAKVFQLWNYLGKIIQEKGFVDRLIKDPTFENFKENLSQ-- +>tr|B9Y2V8|B9Y2V8_9FIRM PRD domain protein OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_00133 PE=4 SV=1 +--RFSSDLFWR-GQAKNRQEIVARLIAMASRSyHLP-KKFEELVLEREKLSSTYFGSQVAMPHPLYPI---TAQTFIAVAVLDKPVAWTED--QKVRIVLLVSTEMnnPKAFQLWPYLSSLISSPQQIHEILRESTYENFIAVFRA-- +>tr|A0A1C7HNZ1|A0A1C7HNZ1_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium I46 GN=A4V01_03675 PE=4 SV=1 +--LFSKSRFIS-KlSLHNKNEVIKALSTLSTNIvNE--NELYKSVTAREINGYTSYGNLIAIPHPETLL---TKKSFCSVAILTQPIPWSET--NYAQIIILCCASKqsSKDLQmLFNFISLLFNNKKEVEKIINNPTYDNFINSLQN-- +>tr|A0A1M6MLC0|A0A1M6MLC0_9FIRM PRD domain-containing protein OS=Propionispora hippei DSM 15287 GN=SAMN02745170_03475 PE=4 SV=1 +--IFYKDLFFI-SHGENREAIIRRLCQSATAHfHIEDGDLQNAVLQREQLGSTFFGNGIAAPHPISAV---SSDSFVAVAALPQPVEWDKD-KNMVKLVLMICIGKnnTKAFHLWNYLSTVFANRYFAEQLMVNPSYHNFVRLLKE-- +>tr|A0A1C5ZQN9|A0A1C5ZQN9_9FIRM Ascorbate-specific phosphotransferase enzyme IIA component OS=uncultured Flavonifractor sp. GN=ulaC PE=4 SV=1 +-DLLLPGLMRIDVPCRNWQEAVYQSTQALELEGYVTEAYKHAIVRNLQEFGPAmvMFPGVLIAHASPA--DGCRKLGFGFMSLRSPVSFGNKSNDPVKLVFTLSVVDsSSHMEAMIQLFNMISEKPVRETLFRARTKQDVLSILQKE- +>tr|A0A1T4XY36|A0A1T4XY36_9CLOT Transcriptional antiterminator, BglG family OS=Caloramator quimbayensis GN=SAMN05443428_11514 PE=4 SV=1 +-DLITWKTILLNAECSTWQEAIKLGTDILSENNYVDDRYYDAIMENFKNIGPYmvVAPGIVLSHARPE--DGVKKLSMSLVTLKNPVNFGSELNDPVKLIITIAAIDnESHLKALSQLMELFMNSNDMNEIYKAKTKEEIINIVTKY- +>tr|A0A143Z9W4|A0A143Z9W4_9LACT Phosphoenolpyruvate-dependent sugar phosphotransferase system eiia 2 OS=Trichococcus ilyis GN=TR210_2732 PE=4 SV=1 +---FNPDHFYYINEPMTKEDLLQRMVGNLVNDHYAPDTFLASIMEREKLGQTNLNNMLAIPHPMSL---MALESVIPVAVIPEGIDWGDG--HSVKFVFLLSITKQDYentDYFYDLLLELMDQTEKQEQILNNPSFNHFMAVIEN-- +>tr|A0A0F5Z222|A0A0F5Z222_LISSE PTS sugar transporter subunit IIA OS=Listeria seeligeri GN=UQ68_12150 PE=4 SV=1 +---FFGADFFARSKLTSKSAILEEMVNSLRAQDIVGADFLSSVLERERLGSTVLGTGIAIPHPLGL---MAKDTKIVIRILDKPIKWGQK--QTIQVIFLLCISKNDYeeaINIYELLVGLVREE-YLEKLANLAGFKEFIRLAEE-- +>tr|U3GUT6|U3GUT6_9CORY Uncharacterized protein OS=Corynebacterium argentoratense DSM 44202 GN=CARG_05685 PE=4 SV=1 +-----EDLVVFDVDVDDhPYAVLAFLSELLHEQQRCTdpQQLLSELWDRELKMDTGIPLGIAIPHCRS---TAITEPTVAMLRLAQGVDFSGPD-GPSDLIFCIACPatsGREHLKILSRLSRHLVDQAFVASLRSASSPDAVAARINQ-- +>tr|A0A142WP81|A0A142WP81_9PLAN Hemolysin C OS=Planctomyces sp. SH-PL14 GN=tlyC PE=4 SV=1 +--ALAAGNVLLEMKAETLEEAVRELASSIPPEsvPSFSQ-LCDLAGTHLASDVVDAANGVAIPHLRCP---GAKRPIIVIGRSTEGIRLRPEVETPTHLFFFVVTPAerpHAQSFFVEGMTTIARSEVIRGRLLIAETPVQVFEIIAA-- +>tr|M8DB60|M8DB60_9BACL Uncharacterized protein OS=Brevibacillus borstelensis AK1 GN=I532_21185 PE=4 SV=1 +--LENGLSVAGKMllselNDHLPFELVSEDVDTVGGWlySQLEEDiAVGASV-------ELEDHVFTVAQMDNH---RVTRVTIKQLVRPQAEKQEEPEMSAV-------------------------------------------------- +>tr|A0A1F9RWN5|A0A1F9RWN5_9BACT Uncharacterized protein OS=Elusimicrobia bacterium GWA2_69_24 GN=A2X36_13415 PE=4 SV=1 +--YWVPEAFDPKLEGASRSEVIARLLERLHAArPEFDRKaAYEAIWKREQGLTSAIGKELALPHGRLQ---DLNKPLIAIALSQEGIPFEAPDGRPVKIIFLILTPLkepAAQLRILANIAHLMSNAALRRRLQRARGPAQVGEILRS-- +>tr|A0A1G1BVH9|A0A1G1BVH9_9BACT Uncharacterized protein OS=Lentisphaerae bacterium RIFOXYB12_FULL_65_16 GN=A3K19_00610 PE=4 SV=1 +--FLVKEAVLTKMKARTHESAVRELAFALASHtRGLQPSmLADRAMRREREAPTAVGRGVALPHVRVE---GLPRTLVAYGNCAEGIDFKAADGHPVRHIFLILTPKenpREQLRALSRIAALATSDVLLGKLNEATTVDAVLAVVRT-- +>tr|A0A1F9VRW6|A0A1F9VRW6_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RIFCSPLOWO2_12_FULL_59_9 GN=A3G41_05625 PE=4 SV=1 +--LFHEGVVVLDLKAETKKEAIAALVHALCKAkGLQNEHqIFSSVWGREISFSTGIGNSVALPHSAIA---GLSKFMLAFGLSRNGIDFQAPDKQKTHLIFMILSPMeqaGDYLQLLAKLSRLIRNSTIREQIMTTTRKETLLDLFDA-- +>tr|A0A1F5UXX9|A0A1F5UXX9_9BACT Uncharacterized protein OS=Candidatus Firestonebacteria bacterium RIFOXYC2_FULL_39_67 GN=A2452_11250 PE=4 SV=1 +--LISKKGVIADIGDIDKKEAVNRLIKKAAALyPEINEKeVSDEVWKREAMLSTAIGSELAIPHARVE----ISNTIIVFGRSKEGVEFNAPDKLPVKLIFLVLTSNsspIMQLRILAKIAKVAESYIFRQKIMEAKNEDEILNVIRL-- +>tr|A0A1G3D549|A0A1G3D549_9GAMM Uncharacterized protein OS=Pseudomonadales bacterium GWC2_63_15 GN=A2180_10220 PE=4 SV=1 +--QPGKLLVRGDTplfklERLLEIDLDHVEAETLAGLvyETLKRVpDEDEVL-------QVDGLQIVIKKMRGP---KI---VLAKVLRFPG------------------------------------------------------------- +>tr|A0A1R4R4P0|A0A1R4R4P0_CLODI Probable licABCH operon regulator OS=Clostridioides difficile GN=licR_5 PE=4 SV=1 +---FFDKNLfIVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMEL---SSIRTKICISILNEPIYWSED--STVKLIMMLAINKDDYikiNSIYDILLKIIHDNDIRDSISNCNDFDNFLSIIKS-- +>tr|K1ZMT1|K1ZMT1_9ZZZZ Uncharacterized protein OS=groundwater metagenome GN=ACD_62C00363G0005 PE=4 SV=1 +--ALAIESIHLNLKADNANDAITQALSRTPQEVLplSPKQIIQALTDRGHQIVVYLGDGIGLPHARVE---GLKKPFLMFLRLKKGITCESSH-DKARMLFVLLTPAgqpRTHQKILAALATLlQESEYVKDRLLTARTPTQIMDVIRT-- +>tr|Q17V80|Q17V80_HELAH Putative integral membrane protein with haemolysin domain OS=Helicobacter acinonychis (strain Sheeba) GN=Hac_1750 PE=4 SV=1 +------EEGVFELEGMLDLESVEEVLH------IqfDKE----------CEQVTLGGYVFS-LLERMP---MEGDTI-----ISHGYAFEVLSVDGARI----------------------------KRLKAIKENKEED------- +>tr|A0A1G0Z667|A0A1G0Z667_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_50_93 GN=A2X45_07935 PE=4 SV=1 +--ALTVDRVLLDVEGKSIIEAAEYALGRLNPNDLpmPTEKIMLSILEREKLMSSYVGQNIAIPHARLK---SLARPIVVVGRLKEPFPSPVPS-ETVDLIFILLTPAdipRVHQVLLSHIAQMLDSDFLSDRLINAKKPGELFEALKT-- +>tr|A0A1G0Y3J8|A0A1G0Y3J8_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_49_21 GN=A2X48_03015 PE=4 SV=1 +--RLTTDRVLLDVEGSSITSVAENALKRINPSDLpmPVETIMLSVSEREKIMSSYVGKNIAIPHARLK---SLARSVVVVARLKKPIPSPVPN-ETIDLLFILLTPAdtpRIHQALLSHIAQMLDSEFLADRLINAKTSSELFDALKT-- +>tr|A0A1M6N9Q2|A0A1M6N9Q2_9BACT Hemolysin, contains CBS domains OS=Rubritalea squalenifaciens DSM 18772 GN=SAMN02745181_2784 PE=4 SV=1 +--N----EQEFVVEG-------SITLNELSDHEPevDIE----------SGEVTTVGGYITQQMGRIP---EPGETLDILGYEAK---VTSTDGRRVGQV--HFRKFaeaESSEGAEEEVA----------------------------- +>tr|R6YSD2|R6YSD2_9ACTN Transcriptional antiterminator BglG OS=Collinsella sp. CAG:398 GN=BN642_01480 PE=4 SV=1 +--YLPRNLFFAHEHFEGKQEAIAVLVARMRaaYPDEIPENFEELVWQREEAAPTSFGNLVALPHPLFAV---STMTLVAVALLDEPIEWGTE-TGPVQAIFLMSFSRlpETRLdGFYRPVASLLNDGAAIEELLRTQRYEQLIGELRK-- +>tr|F2N8U7|F2N8U7_CORGP Transcriptional antiterminator, BglG OS=Coriobacterium glomerans (strain ATCC 49209 / DSM 20642 / JCM 10262 / PW2) GN=Corgl_144 +--FFKKSLFFPHMSTGTKEEALDYLIDRVAEREPVHEDFRNLVWRRERLVATSFGNGVAMPHPLEPA---AETTIVCIGLLDEPVAWDDS-GCDVRAIFLVAFAPdvDDSLkSFLSVFTDILSSARDIDLLVQHQSWKTFADIVAS-- +>tr|A0A1Y3XML8|A0A1Y3XML8_9ACTN Uncharacterized protein OS=[Collinsella] massiliensis GN=B5G02_08235 PE=4 SV=1 +--FFREELFYPHLKAHDEAEVLDMLCRNLASIGGYGPTLRELVQAREDLMSTAYGNGVAVPHPLEAL---KGNTLACVALLDEPVAWGQE-GVSVDTVLLVAYGTddVSEMsEFHRVVVNLLFDNDGTRRLREIGDFESFSSLIGE-- +>tr|A0A243W329|A0A243W329_9ACTO Uncharacterized protein OS=Actinomyces sp. CtC 72 GN=BW737_04810 PE=4 SV=1 +--VFSPELFVPHLDARTPHEAIEVLTQCARTRYDLPAVFLDSVLRRETLAPTDFGNRVAMPHGEVAM---SEETFIAVGVLDEPIRWTR---NLVQVVCLVSISTreGKDLqQFYQDLSRYLMSEEHITTLIKSRDFSAIVRSIRE-- +>tr|A0A1V6DK19|A0A1V6DK19_9BACT PTS system fructose-specific EIIABC component OS=Verrucomicrobia bacterium ADurb.Bin122 GN=fruA_2 PE=4 SV=1 +--LLDPSRIQLQVQSTRRTAALNEVARLLSGHPDVlnYDGFYQALLERDRLDTTCLGNGIALPHARTE---HTKAIVMAVGRSTTGVRFENSGscGDTVHLMFMLGTPKnkpGDYLQVVSALCKLLKDASQREALLAATTPEEFIQLIV--- +>tr|W5XR64|W5XR64_9CORY PTS system, fructose-specific IIABC component OS=Corynebacterium casei LMG S-19264 GN=CCASEI_04140 PE=4 SV=1 +---IADDIVFLDAEFSSRDDAIAALVGAAAEAGRITnaDDVVAAALAREKQHSTGVDHHVAIPHARSA---AVSKPTLAFARLSEPgVVWAEGE-KPSRLISLIAMPEdagKAHLKLLSKLARHVMNQEFREELYAAATPADAVNKINS-- +>tr|A0A1V4R4A3|A0A1V4R4A3_9BACT Uncharacterized protein OS=Candidatus Cloacimonas sp. 4484_143 GN=B1H06_06705 PE=4 SV=1 +--IIDKNLIVIDPPVKNKKELFEGMVNHAYSHDYILneKKFLDALLEREKMANTELIQGIALPHARSS---VTEKLFLSIIIIKNGIDYDNPDLGPVKIIFFFGCDnnsNKEYLQLLAKSNRLLKTAGFHSRLLACSTVEDVLALMNEY- +>tr|A0A0P0RDT8|A0A0P0RDT8_9BURK PTS IIA-like nitrogen-regulatory protein PtsN OS=Paraburkholderia caribensis MBA4 GN=K788_0005709 PE=4 SV=1 +--LLSPGNVLLDTAAVDRAALFAQVGAFCETHyGVPAGQVIEGLNTREALGSTGLGQGVAVPHSQI---AGLLTAVVLYVRPRMPLDFDAPDAKPVRDVIALLVPegaNTMHLNLLADVAQRFCDQHFRERLHACGSASEVCRLFSSA- +>tr|A0A069PV52|A0A069PV52_9BURK PTS IIA-like nitrogen-regulatory protein PtsN OS=Paraburkholderia glathei GN=BG61_32950 PE=4 SV=1 +--LLSQDDVLLGLNIADRPALFAELGHFFEQRcGLPATTTTAALAAREELGSTALGLGVALPHGHI---QSLNRPMAAYVCPADPIAFDAPDGQPVKDIIVLLVPewgNSMHLHLLADVAQRFCDHHFREQLHACADVRAVSELFRGY- +>tr|A0A163P3E1|A0A163P3E1_9ACTN PTS sugar transporter subunit IIA OS=Propionibacterium avidum GN=A2U93_08085 PE=4 SV=1 +--FLDPTLFFTGGSFDSWRETLDFMCEAMERNGIVPDGFRESVFLREGYSSTVFFRRFAVPHAMDF---LAYETKIAILIPSTPIDWEASD---VSLVLLLAINEgdyDDFVRFYQPLIRVLYDQELFTELRSISSYHEFMKFLDK-- +>tr|A0A0B7NXG8|A0A0B7NXG8_PROFF PRD domain protein OS=Propionibacterium freudenreichii subsp. freudenreichii GN=PFCIRM138_09570 PE=4 SV=1 +--FLSPELFFRDLEFASARETILNLCGHLQEAGVVPGGFTQSVLLRESYSSTIFAQRFAVPHAMEF---MASETKIAILIPKKPIDWGEdSR---VSMVLLLAIKNddyESFVAFYQAFIRALYDPDVFSRLRAAEGYVEFCRVLVD-- +>tr|U2N4E0|U2N4E0_9CLOT Transcription antiterminator OS=Clostridium intestinale URNW GN=CINTURNW_2658 PE=4 SV=1 +--LYKKDYFEIIEGHIEYRKILEDMSQKIENSGYGGENYSQYVMQREDYLSTIYLNGVALPHPIQ---MCARKNLISVAILKEPCIYEG---KEVRIIFMVSLTKDgyeLLKDVTKRLYEIMNKDELVEELCTAKSYEQFMAVLNT-- +>tr|A0A0X8GYW6|A0A0X8GYW6_9FIRM Uncharacterized protein OS=Erysipelothrix sp. LV19 GN=AOC36_02885 PE=4 SV=1 +--LFKEALFTVYHN-LSYCDIIKNMAQKIVDIGYAEPSLVDSVMRREEVMSTIFLNRVATPHPLE---MSGVTDCIHIGIVSED---LE---EMPKVIFLISLKKGqltLHQRISKFVFEVMSDADLVNNLHKANNYLEFMLLLNE-- +>tr|A0A1L8SWS7|A0A1L8SWS7_9ENTE Uncharacterized protein OS=Enterococcus devriesei GN=RV00_GL001691 PE=4 SV=1 +--LFSQSLFQIETH-RAYSDILVDLADQVEE-QVAFAGYKDSLMERENYLSTIYQNGIAIPHPLI---MSGKENRLAVCLLPEGTSGTE---RSPKIIFMVSLKAEqldVHQIISKELSKLMNHPAAIKTLVESKDYHEFYYTLKR-- +>tr|A0A1L8WX06|A0A1L8WX06_9ENTE Uncharacterized protein OS=Enterococcus raffinosus GN=RV13_GL000885 PE=4 SV=1 +--LFDRKWFQILDPPAEYLTLLENEGARLEELQWAEQGFKQSVLEREKLIDTIYQHGIAGPHPME---QAAIKEVIDVILLKRPLTYRE---KQVRVIFLINIKKDhlnLHKEISRLMIKMMDDPTLDTQLTKITNFQDFMSYMKS-- +>tr|A0A1L8V7R4|A0A1L8V7R4_9ENTE Uncharacterized protein OS=Enterococcus malodoratus GN=RV07_GL004091 PE=4 SV=1 +--LFEPEWFQIEEQADNYLQVLENEGARLEKQGWVEQGFKQSVLNRERMIDTIYQQGVAGPHPME---QMAVKEVIDVILLKKPLMYRD---KQVKIVFLINIKKDhlnLHKEISRLMIKMMDDPMLELQLTKIKNFQDFTSYMKS-- +>tr|A0A223K4T6|A0A223K4T6_LACSK Uncharacterized protein OS=Lactobacillus sakei GN=LBS_07600 PE=4 SV=1 +--LLKPNLFSVETI-QNYDVLIKKMAEKMMSKGYADDNFQKNVVLREQYMSTVYNNGIAMPHPIE---MKGKQSAIAVSVVKPELRVGK---RVVRLVFMVCLAKEdfhFYSNISNGLFQLMQDNHKISDIYHKPDLQRIINIFKE-- +>tr|A0A150LPJ3|A0A150LPJ3_9BACI Uncharacterized protein OS=Anoxybacillus flavithermus GN=B4168_1017 PE=4 SV=1 +--LLGEDRFFILDHNKDYWENICVMVDSLYEKGYVDADFKKRLKEREEKGTTIFDSYIALPHTLNC---ASENVVLSLGVFPRPLqTFSGK---EIKLVFLLGVPQHMkqdsslLVKIYDEIITVANDRQLINRLALSKSYDEISHLLEHN- +>tr|C5USF2|C5USF2_CLOBO Putative transcription antiterminator OS=Clostridium botulinum E1 str. 'BoNT E Beluga' GN=CLO_3391 PE=4 SV=1 +--MLDKKLVFYLNK-NNFMDNLEDMLDSLIKSNIVSNEYKNRVIAREKKAGTAFGGYIALPHAVDE---KVNSVIVSYGILDNLIMVDGK---EVGLIILLVIPSESqnsqdvIVKTYQEIIDLSSDKKIVQKLIKSKNYKEFKEVLGRR- +>tr|A0A165X218|A0A165X218_9BACI Transcriptional antiterminator BglG OS=Aeribacillus pallidus GN=AZI98_13955 PE=4 SV=1 +--LLNKDKFFVLDTNKGYHENVNDMIDVLVKKGYLDEGFKERLREREEKGSMVFDRYISLPHTVNY---KSNQIEMAIGVFPEKAVVDGK---EIKLVFLLGIPEKAdndaslLIKIYDEIIKIASDQKQVEELADAASYEDFTKCLEQA- +>tr|W7KTP0|W7KTP0_BACFI Transcriptional antiterminator BglG OS=Bacillus firmus DS1 GN=PBF_18169 PE=4 SV=1 +--LINKDKFFHLDSRKSYQENVMNMVDHLVDKGYLDAGFKERLTDREAKGSMVFDRYIALPHTSNT---ATDKIELSLGVFPENVLADGK---EIKLVFLLGIPKQTdydaslLVKIYDEIIRIAADDQLIDQMAHSSSYEELGKCLIYA- +>tr|F3A4X1|F3A4X1_9BACL Uncharacterized protein OS=Gemella haemolysans M341 GN=HMPREF0428_01779 PE=4 SV=1 +--SMREETFFKCDSKKTYADNIDFMIEELIKQYLVDDKFLERIREREKKSSMIFEKNVAFPHTINK---LGDDLIIALGVSEKGF-KDNE---DLKLIFMACVPEG-ekngliLAKTYDELISIIKDEKLITDISKIDNYDLLVNYFIKN- +>tr|A0A1M5ZAK0|A0A1M5ZAK0_9CLOT Lichenan operon transcriptional antiterminator OS=Clostridium intestinale DSM 6191 GN=SAMN02745941_02712 PE=4 SV=1 +--SIPQEQFFIIKR-KDYVGAIDYMVTNLSEVLTLDKDFKKRLIERENKSPTAFDNYVGLPHAVNY---GSDKFSISMGILEEPIVWGKN---EVRLIIMLIVPDENsidpdmVISVYEEILKICQNKKFIEELCKVRSYKEFLDLNRKE- +>tr|A0A1M4W0A2|A0A1M4W0A2_9FIRM Lichenan operon transcriptional antiterminator OS=Alkalibacter saccharofermentans DSM 14828 GN=SAMN02746064_01119 PE=4 SV=1 +--ATKPNLFFKTNL-DDYIDILKEIIGKLFNQREVDEGYLDRVLDREATYPTTFANGVAMPHAINK---GGERLMISIIIPEKEVNYENS---AVRIIFMLLIPEIMdespevLIKTYEEILKICQNEDLLGKVINAKDYFELTNVLVKE- +>tr|A0A221TMH7|A0A221TMH7_CLODI Transcriptional antiterminator OS=Clostridioides difficile GN=CGC51_12505 PE=4 SV=1 +--LLDEDKFMILNE-KTILASLEKMMDHLMDLGCIDEKFRKNIVNREEKSPTVFDKGLLFPHSINE---KSDKFLMAVGILEEPIEYANR---SIKIILMTMFPCENkidsdlLVKIYEEVLKIGQDVKLTNKISKCRTFLEFKKVLLKN- +>tr|A0A1F5YM94|A0A1F5YM94_9BACT Uncharacterized protein OS=Candidatus Glassbacteria bacterium RIFCSPLOWO2_12_FULL_58_11 GN=A3F83_02290 PE=4 SV=1 +---FNASNVNLDLEAQGKDEVLLELINLLHLDEKAKEMLFKMLKKRENLGSTGIGKGFAIPHCRSL---VVDKLNVAFARQRQGIDFNSIDDKPAHYFFLIVAPPveisNYYLPVLGKVAQFCKISDITSRLDKLTKVEDFLKLLAD-- +>tr|A0A1G3QNM8|A0A1G3QNM8_9SPIR Uncharacterized protein OS=Spirochaetes bacterium RBG_16_49_21 GN=A2W19_17170 PE=4 SV=1 +------------TRADEKHLVIKEILTMLEDMRRIDsaERFYAHIIHRESLENTGIGRGLAIPHIRTE---TVNDLISVFAVSRNAIEYHSYDKIPVRYILLSIVPMeesTKYLYLIGMISWIFMDEKRKKPLGQAENRTQIYNVLKKN- +>tr|A0A1V5W984|A0A1V5W984_9SPIR Nitrogen regulatory protein OS=Spirochaetes bacterium ADurb.Bin218 GN=ptsN PE=4 SV=1 +------------INSTEKQPALKELLSELQTQSLIEnsNRYYAQIAHRESLENTGIGNSLAIPHARTE---TVKELITILGICNSPLEYQSIDGRPVRYILLSLFPTslsTKYLYLIGMMARIFNNPENNSFLSQEHSPEEIYYFLNEK- +>tr|H3NQM9|H3NQM9_9FIRM Uncharacterized protein OS=Helcococcus kunzii ATCC 51366 GN=HMPREF9709_01640 PE=4 SV=1 +--ILKPEFMRFEIEAKDWKDSIVKSSRILLENDIIEERYTDAMIKNIEEYGPYivVSKGVAIPHASSE--EGVKKTAMSLIKLKNPVPFGVEGLDPIQYVISLSSLNNEHFYAFFDLVNGLQNEEIKQEFISANSSSDMEKVLKK-- +>tr|A0A1J6EXE8|A0A1J6EXE8_9STAP Transcriptional antiterminator (Fragment) OS=Staphylococcus equorum GN=A4A34_04945 PE=4 SV=1 +----LIELFAIKSNVESKDELLSEIESDLKALHYIKSDFFEKVNEREEVATTAYGNLIAVPHPVTP---SAKQSFIYIVKLDKPIQWGDKD---VQLVFCLGLKSQttvDMEPIFKRISHIINDFSLVVELLNQSNEKDLKETYFD-- +>tr|A0A239V294|A0A239V294_BACPU Transcription antiterminator BglG OS=Bacillus pumilus GN=licR_3 PE=4 SV=1 +----KKELVFTKRAFQTKEEVITFLTKKVIDMGLAPAELTPSVMEREEAAPTSFGHYTAIPHPMTP---LTEETFWAICSLEKPIIWGEKK---VQFVCLLCVEKEnakDLKGMYRLLGELVHNVKFIQHLIACDTFEDMLDIMYK-- +>tr|U2UT44|U2UT44_9ACTN Phosphoenolpyruvate-dependent sugar PTS family porter, EIIA 2 component OS=Olsenella profusa F0195 GN=HMPREF1316_0722 PE=4 SV=1 +---LRPDFFKLNFYPGNYDELIAAMVLDCLDKGLVGEGYLEKVLEREALSPTVFDNLVAVPHTVEP---AALRSFLYLVINDRPVAWGQSS---ANIILLLGISEndrESFTNFYSDFLSILSNAKNASELIGSVSYEDFMRRLT--- +>tr|A0A223L845|A0A223L845_BACCS Transcriptional antiterminator OS=Bacillus clausii GN=BC8716_18185 PE=4 SV=1 +---FDKELFMKNVYLDSDEAYIEFMSNLLHKKGYVSKEYGKSVLERERMSSTAFNNNVAVPHSMHM---DATKTGICMIILDRPVTWGKEK---VQVIVMISINKqqrELFSPFFEGVINILSEWRNVHELIKAKDYDDFMDKMM--- +>tr|Q6Y9A9|Q6Y9A9_BORHE PTS system fructose-specific IIABC component (Fragment) OS=Borrelia hermsii GN=fruA2 PE=4 SV=1 +-DLFSKKLILLNYEAKSKDDVIEKMADMLNENGYLSnkENFITDIKKREEISGTGLEEYIAMPHAKG---NFVAKHGIAILRVtGEGFDFDASDSKPSRLFFMIAVPanttGDTHIKTISYLNNIFNNEILRQEIMSTNDISRFLEILL--- +>tr|A0A1W1X1Y5|A0A1W1X1Y5_9DELT Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Desulfacinum hydrothermale DSM 13146 GN=SAMN02746041_00387 PE=4 SV=1 +--FLDDDLVVLDLQARDRMSALREIMEKIPQNGRIRnkEKALRDLLDREALSTTGIGGGFAVPHVLSE---EANLPTLLFARSEQGVDFQAKDGQPVHLILVAfANPRkkNFFVQCLYHAVQILKDPEQFQRLMQAATPEEVLSVLGRR- +>tr|D5H7D5|D5H7D5_SALRM Sugar phosphotransferase system protein OS=Salinibacter ruber (strain M8) GN=SRM_01019 PE=4 SV=1 +--LLDPEHVRIGLAEPSKNAVIDALVDVLAGHGAISrlDDVRAAIFAREEKMSTGVGKGLGLPHAKTPA---ASNTVAAFATTDEPVDFGAVDDVPVQILLLLVGPEehkSQHVKILGRISRLVSREPLRERLLDAETPKAVIKTLREG- +>tr|F2B1U3|F2B1U3_RHOBT Sodium/hydrogen exchanger OS=Rhodopirellula baltica WH47 GN=RBWH47_03749 PE=4 SV=1 +-DFLQENRIMVDLDGDTE-EIFQKLTNLLYATTPmstPQEKFLESVRARESSQTTCLGTGLMIPHAIIDEPG-DNEVKGVLGISKKGIKLNTPDGRAVHAVLLLATPEssrKRHLEILSAFATAItRDINIREQLYRSRSAAHAYEVLH--- +>tr|M5UL15|M5UL15_9PLAN Sodium/hydrogen exchanger OS=Rhodopirellula sallentina SM41 GN=RSSM_00004 PE=4 SV=1 +-DFLQEHRITVGLTGDDREATVRELTSQLYATSKmevNQEEFIQRVMARDAEHSTCLGNGLMIPHAILEDGE-GREIRGVLGISPEGLNFDTPDGRVVHAVLLLATPEverSRHLQVLSAFATAItRDANLVEQLYHARSPAHAYEILH--- +>tr|A0A0J8GC81|A0A0J8GC81_9LIST PTS system IIA 2 / PRD domain protein OS=Listeria fleischmannii 1991 GN=X560_1126 PE=4 SV=1 +--EFKEQLIVTKKHVNTWQQAIRLGTEVLFQTGCIEKRYTEKIIQNLKAFGPYmvIAPGIVLAHASPK--DGVLKDSMAVTVLEEGISFFDRYGEPVRLIFTLAFESKEARRLVEQLMKVVLNEEQVSRILSAKSHKDIYNYTKS-- +>tr|A0A0Q3WVB6|A0A0Q3WVB6_9BACI PTS fructose transporter subunit IIA OS=Bacillus shackletonii GN=AN964_02515 PE=4 SV=1 +--IFSSETIVYGEKANTWRQAIALGTNNLLSMNCIESRYYENIIKSITKYGPYmtVAPGVVLAHAGPD--DGVLKDSLAVTVLNKGVSFYDRYNIPVQVIFTMAFHSKGTHLLVERLAQLALNSDKVRLLTEASSKEEIYQLVKA-- +>tr|A0A221M9L4|A0A221M9L4_9BACI Uncharacterized protein OS=Virgibacillus necropolis GN=CFK40_04490 PE=4 SV=1 +--KFGEEHITINKGKLRWDEGIKLGTSALIDRTYVTPNYENKITHNIRKYGPYmvVAPGVMIAHAGME--DGVIEESMWLTILPYGIRLNDRFDEPITVIFTLAFKNKGTRHLMEKIANLALNKEKMNHIIELSSSEEIYDFVSA-- +>tr|A0A0V8QCH9|A0A0V8QCH9_9FIRM Uncharacterized protein OS=Acetivibrio ethanolgignens GN=ASU35_13315 PE=4 SV=1 +---VDTEHIMIVRKKTERDAILKEACEILFDGGYVKKEFFDDVIKRELIESTAIGNGVAIPHGMPE---NVIKPKVFLIQLKYPVNWEG---KMVRTIFLLALNFnniATTKAFFSDFTRITGSEERIHAIQKCETVEEIWDLLKD-- +>tr|A0A0D6DX31|A0A0D6DX31_9LACT PRD/PTS system IIA 2 domain-containing protein OS=Lactococcus piscium MKFS47 GN=LACPI_1119 PE=4 SV=1 +-----------ALNDLTPVMIRKRLYQRMQQADYVDQTFLCEVEKLEKMSPTSFPSGIAVPHAVA---RVAFKSGVSIMTLRHATIWEN---YPVKLVACIAINQadaRVFNRFFEQFIMLVSDDMNAKKLSSCSSHADFISTLKA-- +>tr|U3BJS9|U3BJS9_VIBPR Uncharacterized protein OS=Vibrio proteolyticus NBRC 13287 GN=VPR01S_05_01730 PE=4 SV=1 +-------------ETEDKNHLLAQSAMCANPS--RQDVLYQALQARETISSTLIGQALALPHIMHS---DVTVPTMVFQRPNAQVVWHQ-NKAPAHLVITLFIPsptDRQTLIPFTRLTRWLLSEPHQTLLLDNLDDFTLRIIIS--- +>tr|Q5DZL5|Q5DZL5_VIBF1 PTS system, IIA component OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=VF_A0711 PE=4 SV=1 +-------------AVLSKFEILKGLSQLIYPK--ESDELLLALIKREERSSTAMAKQIALPHVISP---YVEKPTIAIIRSDYPVDWAS-KMGDVNVIIALVLPekpTKEMIMAATYLTRSLLSEDFSQRLVHTRQPKGLQALIL--- +>tr|F0LNV1|F0LNV1_VIBFN PTS system, nitrogen regulatory IIA component OS=Vibrio furnissii (strain DSM 14383 / NCTC 11218) GN=vfu_A00075 PE=4 SV=1 +--------------LPDKRSALTHIAALANPN--ATSDLLTQLLARECISSTAMAGGIALPHVVSE---HIQRPCFIVFSLDEGLDWQS-AHEPVHLVCAVLLPaalHREWLIAVTRLTRWFIADTSAHLLLSARREETIESIVL--- +>tr|A0A0F4NYD9|A0A0F4NYD9_9VIBR PTS system nitrogen regulatory IIA component OS=Vibrio neptunius GN=TW84_15800 PE=4 SV=1 +-------------EIDTKSAAFSLATKCITSS--NPALICEQFAQRELTSSTAIGHGIALPHIMSE---AIDIPSISIVSLTEELDWNSPVQGGVSMIIAIALPhnaSRDVLLAFTRLTRSLLDPDYCQLLRTSHEPQALKALLT--- +>tr|M4U166|M4U166_9GAMM PTS system, IIA component OS=Psychromonas sp. CNPT3 GN=PCNPT3_00980 PE=4 SV=1 +-------------TQYNKNKILLSLTRIISKS--SYKPLLSALLAREKISATGIGKRIAMPHILSD---LVDEPWVVVLHSEEDIDWHS-PLGDINLVLALIIPrnaSKDIFRSVISLSRALLDPNFTDLLLQTRDPQELETLLL--- +>tr|A0A1E5CIQ4|A0A1E5CIQ4_9GAMM PTS nitrogen regulatory IIA subunit OS=Enterovibrio calviensis FF-85 GN=A1OS_13850 PE=4 SV=1 +-------------SNLDKHALLAEFALRVadnenrEDT--TQEALFNALYTRENVSSTCMGNGVALPHVMTP---LVSQIHVFIASTAQPLDWLS-KRGEVTRVIGVMLPkppVREHIVAFSTFSQQLLDKTFCRYLEENTSLDIVETIVL--- +>tr|A0A0R1U3K1|A0A0R1U3K1_9LACO Uncharacterized protein OS=Lactobacillus pantheris DSM 15945 = JCM 12539 = NBRC 106106 GN=FC50_GL001224 PE=4 SV=1 +----EPKLFWHLSGHTTKDEVLKPAIDEMRKQQVVNDNFYDEILERESMGSTSFK-NIAIPHPMS---FNSPKTKVAVILNEDGITWDGA---EVNMVYIISISEkykDEFRSIYENLMDFLSDDQKFKSILESRDLNSFYERL---- +>tr|A6DH31|A6DH31_9BACT Nitrogen regulatory IIA protein OS=Lentisphaera araneosa HTCC2155 GN=LNTAR_13897 PE=4 SV=1 +-DLLNPKLILCDLQSESHEMVYLEMLEALKGQCkdIAePRDILKDILEHESLVEMPYNSGFAIPHTRSA---GVNDLHLVLGIHKQGIKLQEHDLEKSKIIILFLVSKetsKIYLLILKALARYFSNPGVSDQLAECATAQEVTDVFQK-- +>tr|A0A1G0YZ22|A0A1G0YZ22_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_44_16 GN=A2017_04880 PE=4 SV=1 +-SILNPDLFFSGIPADNRHAIYKNMLEKATRGIkqSIdPEKIVSEMIKREDVFSIPYEKGVALPHLRSS---MFDDLYIIVGILDSSILLKDNDKDLSRVIIMSLISEktsDTYLKALSAFSRYIIkNGGVVSSLTSCHDGNEFNALLDA-- +>tr|A0A1G0XLD5|A0A1G0XLD5_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_45_14 GN=A2020_04745 PE=4 SV=1 +-SILNPDLFFKGIPVGDRQSIYKSMLEKAAGEIkqDIdPEKIASEMVKREDAFSIPYEKGAALPHLRSP---LFDDLYIIVGIPDSPVLLKNNDKDLSHVVIMSLVSEktsDTYLKTLAAFSRFVIkNGGSVSRLTSCRDGNEFNALLDA-- +>tr|A0A1F4YLK2|A0A1F4YLK2_9BACT Uncharacterized protein OS=candidate division Zixibacteria bacterium RBG_16_53_22 GN=A2W25_03105 PE=4 SV=1 +-DFLDPDLIDVDIKAETKFDAVKELADLFCRKFaDSdKQAILDAVLEREDLGSTSFGRGFAFPHARTD---VVTDLHIAIGIIKEGVKDKGPDDTPIRVICLLLTPRnisKLYLQTLSGLANLARRQGMLECLSAAKSPRELIAIIDE-- +>tr|I4C4T7|I4C4T7_DESTA Universal stress family protein,osmosensitive K+ channel His kinase OS=Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DC +--LISSRRIVIWNQPVEKEYVIRTLVEVAAKDfETCDaEDTIKAVLDREKLGSTFFaNEAAAIPHARIK---GLSSPIISLGLTKQGILQDEAI-SPIGLVFLILTPaeiPSSQVEILALVSRATKDGHLYDRVAESDNPEELLSILRE-- +>tr|E1YG16|E1YG16_9DELT Putative uncharacterized protein OS=uncultured Desulfobacterium sp. GN=N47_J04910 PE=4 SV=1 +--FLKKMSVLIWNKRIEKEEAINRLLDACCSEkTELKKSAWIALLEREKQGETFVGEDVTIPHARII---DLQTPLVALGIGKAGIQDQRSE-RSARIMMLLLSPadsPESHLSMLATISKMARSDKWRKEVLSANKSSDIIKLVAE-- +>tr|A0A1X3HZN0|A0A1X3HZN0_ECOLX PTS system, fructose-specific IIA component OS=Escherichia coli M056 GN=EAMG_04644 PE=4 SV=1 +MAALTASCIDLNIQGNGTYSVLKQLATMALQNGFITDshQFLQTLLLREKMHSTGFGSGIAVPHGKS---ACVKQPFVLFARKAQAIDWKASDGEDVNCWICLGVPQsgeEDQVKIIGTLCRKIIHQDFINQLRQ-GDADQVLALLNQ-- +>tr|A0A0Q3W0M4|A0A0Q3W0M4_9BACI Uncharacterized protein OS=Bacillus sp. FJAT-25509 GN=AN960_18690 PE=4 SV=1 +--LFHTELFYIEESKesFDYKAFIKEKAKSVVELGFAAPNYPALVVDREEKISTILQYGIAAPHALK---MVAIQDSISVVIFKNPPTIDG---KVVQILFLINLRAGdlfLHKELSRLFLHLMDHPETKQKVLKSNNFNDFQYEISK-- +>tr|N9Y3Q8|N9Y3Q8_9CLOT Uncharacterized protein OS=Clostridium colicanis 209318 GN=HMPREF1092_01712 PE=4 SV=1 +--KLDDVLFKRRKGGkdINYKNFLREEAKMLIKKDIVLEDFEELVLLREEKLSTAYKNNIAAPHGIE---MNAKKNVLSVTVFDNPIEWGD---KKITIVILIGMKKGslnLHRVIANKLFRLINDEEERNEISKCQSSEEFIKAFKI-- +>tr|A0A1Y3VII7|A0A1Y3VII7_9FIRM Uncharacterized protein OS=Faecalitalea cylindroides GN=B5G15_07090 PE=4 SV=1 +MKVIDHNFIFIDTDFKTQKELFLFLAKQVFSskRGNDLDKIVEGFYEREQEFSTAMDNYIAIPHCRNE---NILQATVIVVRNKTEIKWTDNE--NVKLIFALLVPGsnenQMHIRILAQVAQLIMEEDFIDLVNKAKGDDQIYQRLS--- +>tr|A0A011RNX5|A0A011RNX5_9LACT Transcriptional antiterminator, BglG family OS=Alkalibacterium sp. AK22 GN=ADIAL_0871 PE=4 SV=1 +---VKEAFVQVADRADSFKEAISLALKPLVDHKYIEQAYVSEVIHAFAENGSYmfVAEGIAIPHARSE---QVKETGFGILKLHEPVRYSDN--QTIDMLICFSSRDnLGHLDALINIVDYVKTPEFLSALRSIRTADELArHIL---- +>tr|A0A1L8PHB8|A0A1L8PHB8_9LACT Uncharacterized protein OS=Alkalibacterium sp. 20 GN=AX762_01720 PE=4 SV=1 +---VPKSHIQIVESVDSWKEAIVIATRPLVDNSYVAESYIENVTESFEKYGYYmfIGDEVAIPHARSDK--DVFKTGFSILILKNKVQYSED--SAIKVLICFASMDnLEHLDTLVNLIEVVKSDEFKQILNQNITEEAVFQLI---- +>tr|A0A0G7ZNG7|A0A0G7ZNG7_9MOLU | fruA / EIIABC-Fru |:139640 Forward OS=Candidatus Hepatoplasma crinochetorum GN=HEPPS_04980 PE=4 SV=1 +------EKLIVDKDFNSSEEVLHEIANLLKANNFIEDssTAYSNLLAREKQISTGVGNGIAIPHAEIK---DLEEPKIAVIRSKKGIEWNSIDSKKVNLIISILVPKenrEKHFEILTKLSSSLVEAKNIEKFKNAN-AKELVDYIE--- +>tr|A0A1L8WVS3|A0A1L8WVS3_9ENTE Uncharacterized protein OS=Enterococcus raffinosus GN=RV13_GL001139 PE=4 SV=1 +--ILTVERIKLDQSCDSWQSAVEAAGQLLLADELITSEYIQAMIQMVVDYDSYivISPGVAIPHAEFS--HGAKKIGASFVRLAEPVSFNHQKNDPVKYVIAFSLPEGVSIgTCLYYFTEILATENFLALMDQCQSEEAVMNQLRK-- +>tr|A0A0F4LIB8|A0A0F4LIB8_9LACO PTS Fru IIA OS=Lactobacillus kimbladii GN=JF75_12790 PE=4 SV=1 +------------FDVTDQKAAFQIIADIVAPKMEVsKVTVLKSLLTREKTANTALVKGIAIPHIILEL--D-FTPWLLIIKSQTLVaDWDCLDDSKVNTLICLIVPRiikksNKSFKKIIQIIDKLADDNVIAEINKAESATEIVQILKR-- +>tr|V6Z2V6|V6Z2V6_STRAG Uncharacterized protein OS=Streptococcus agalactiae LMG 14747 GN=SAG0136_01325 PE=4 SV=1 +------------MEELTKDKALLKIALFLSKEMKTdTRCILNSIVERETIANTGLEKGIAVPHVIIEN--N-AISNahLAVITFYPPVlDWLCNDETAVDIALCIVLPKsydlkTKNIEKLTKIFKSLADEEFINSLQLKRNSIDVIRKLEN-- +>tr|A0A0R1T4P9|A0A0R1T4P9_9LACO Uncharacterized protein OS=Lactobacillus saerimneri DSM 16049 GN=FC54_GL000508 PE=4 SV=1 +------------LTGANKQEALQQLAHAAATTLNLdEIEVKATLMTREALADTALISGIAIPHIIIDK--E-FTPQICVGLLASPLeDWDCLDGTKVHLLLAFAVPQrtlvhQQEIREISEMITQLADEQFCWRVSQAQTVAEVSAILSE-- +>tr|B2KDQ9|B2KDQ9_ELUMP PTS IIA-family protein OS=Elusimicrobium minutum (strain Pei191) GN=Emin_1103 PE=4 SV=1 +--LLDADSVLLVKdPNTSKELLITQLSALACKDlSAEDaKDILERVLKREQGITTTLDTGLSIPHCRVD---ELDSFKAALAVIPQGIKDPLTDNITIKVMFLFLSPSnpaffQKHLQMLAELSEKFKD-SFISKLTQAAAPQEIIKIIKE-- +>tr|A0A1F9TWZ9|A0A1F9TWZ9_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RIFCSPHIGHO2_02_FULL_57_9 GN=A3J74_04815 PE=4 SV=1 +--YLSEQAILIVGSKRGKNELVGLLVNDLCREnGLLSpDVFLAKVLDRERGISTTLDTGLSLPHARMD---GLDKIIAAMAIVPGGMRDPQQADLIIRAMFLFFSPNkqeffPLHLQLLRSVSLLFQP-SFIDQVARAAGPAEAFKLIRD-- +>tr|A0A1F9W9M3|A0A1F9W9M3_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RIFOXYA12_FULL_57_11 GN=A2285_03740 PE=4 SV=1 +--IINPESIIFLEGRLSKEEVVRQLTEKILPAvSGViSrKALFDRVAE-VEKLNPVLESGFYIPHAKFP---DLDGFHAVLGITPEGFPDAAT-GLTVKAVLLLLSPHkpeffQRHLNMLSLLSQTFQP-EFIERLAALKDPAEVYALIQS-- +>tr|A0A1F9S8D2|A0A1F9S8D2_9BACT Uncharacterized protein OS=Elusimicrobia bacterium GWB2_63_22 GN=A2X31_01545 PE=4 SV=1 +--IITPENVVFIEGSPSKEEAVRLLTEKMLPQvGGIiSrKALFDRVAE-VEKLNQVLESGFYIPHAKFP---ELDGFHAVLGILPEGFTDAVT-GLKVRALILLLSPHkpaffQRHLNMLSLLSQTFQP-ELIDQLAALKDPVAVLALIKS-- +>tr|A0A0S8FT88|A0A0S8FT88_9BACT Uncharacterized protein OS=candidate division WOR_3 bacterium SM23_42 GN=AMJ83_04470 PE=4 SV=1 +--YLDKDRILLNVTAEKYRDMLVRMLETSAEQDK--LCVVDNILQREKIMPTAIGKGIFLPRAVLR---DKSKSEVIIATNPSGLSFEDYGPMQAYIIVLFLFSeKDDSAAILAQTLRLLSDDTLRSDILESIAPIDVIKAISEW- +>tr|A0A0K2LEW7|A0A0K2LEW7_9LACO Uncharacterized protein OS=Lactobacillus heilongjiangensis GN=JP39_10870 PE=4 SV=1 +---FPKDNFKVVDDKVERDDIFQTVCDELESKNVIPEKFSDKLKARENMSSTAFG-RVAIPHSMQ--M-IALKTQGYVVIAPKGILWNED-NHEVNLMFLLAVNKeNkqSYRNIFDDLSQIAVDPKNIAELVKARTYEEFIKQLTN-- +>tr|A0A0R2LH36|A0A0R2LH36_9LACO Transcriptional antiterminator OS=Lactobacillus kimchiensis GN=IV57_GL000186 PE=4 SV=1 +---FPKQNFIVSQEKLNRDDLFIQISSILEKKNVVKVGFAQKLIAREKMSSTAFG-SIAIPHSLE--M-IALRTEGFVVIAPNGIDWNSD-NHNVKMMFLLAVNEtNkqAYRNIFDDFSQITVEPKNIAILLKSKTHEQFINTLVS-- +>tr|Q8Y9A2|Q8Y9A2_LISMO Lmo0630 protein OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=lmo0630 PE=4 SV=1 +--LIGIDAIQITSESLTWQTAIQRATKLLSDNHFVLPAYAENIKQIqEELGFYSVkDEEFALFHGNDS--QLVQMNSMALLINEQPVMFGEK---QAKVIFILASKDkKEQIPAIITLTKMTYQTDFISKLEQAKNPIDADRIIKKY- +>tr|A0A1C0BYI1|A0A1C0BYI1_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium MTC7 GN=A4S06_01200 PE=4 SV=1 +--ILTRNMVSLVEQDMEWEEAVHESAKILIDNNYISTIYEMNIIETmKNMGFYAItDDMFSLLHGDHT--AGVNRTGMSLIVNKKKVFFDDK---GVNLIFCLASIDkREHIPAVISLIRMVKQTDFINKAKMCDNTDELYDLLLEC- +>tr|A0A1W9VTR8|A0A1W9VTR8_9BACT Uncharacterized protein OS=Candidatus Cloacimonetes bacterium 4572_65 GN=B6226_01235 PE=4 SV=1 +------------FSPTSKIDAINQMAKLLKEKKIIPetEIITNAIFERELLATTGIGKGLAIPHCRVG---SVDRVIVVASYFEKPIDWNSMDGNPVDLAFMIITPQespELHLKAISKISKAVRTLDFRKEIS---------------- +>tr|A0A1G1Q3Y8|A0A1G1Q3Y8_9BACT Uncharacterized protein OS=Omnitrophica WOR_2 bacterium RIFOXYA2_FULL_38_17 GN=A2243_07535 PE=4 SV=1 +-----------------------------------KEEAFAEAMQREELQSTGLGQGRAFPHVRID---GWKDFVIALGYCKEDLPFESLDDQPVFFICLMISSKdqpYLILKAMSNIIKFLNELENIRSLFENKTPAELADIFKNK- +>tr|A0A1Y0L006|A0A1Y0L006_9MOLU PTS system, fructose-specific IIABC component OS=Spiroplasma clarkii GN=fruA PE=4 SV=1 +--VIATENIYLDIKLKDQAEVFKFIADVAAKKGICEddEGLIAKLKEREEISSTGFENGIAIPHTQFE---KILKPTVLFIRTQTGVWWDSIDGQDAKVFFCILVPKsttqNLHIEILGNLAGKLLNEQFVELISTTKDPQQIVDAIG--- +>tr|A0A235BWV3|A0A235BWV3_9BACT Uncharacterized protein OS=candidate division WOR-3 bacterium JGI_Cruoil_03_51_56 GN=CH330_02130 PE=4 SV=1 +--------------ITNQKAVFQFVARRLAEQRLINnqEVLVEEFMKREQQGSTGVGHGIALPHVATE---AVNQIVVAVVRLNQPMEWDAVDGKPVHLLVMIIAPPdqrKLYLQVLAEVARSLNQPTIRDKVLKARHPAQAVRIIA--- +>tr|A0A1W7A9U0|A0A1W7A9U0_9STAP Putative licABCH operon regulator OS=Macrococcus canis GN=licR PE=4 SV=1 +----QPFLIFTNNTTSDRYKIIEEIGKKLIGQNLVQHEFIKSVAGREYLSSTCIGSGIAIPHGKS---EYVLKSSISVYTLNHPIDWGEE---SVDLVFLIALKEedKkYYQNIYRELHTIMQDKLLLRKIKTERSSLKFLKLFKDK- +>tr|B7C836|B7C836_9FIRM PRD domain protein OS=Holdemanella biformis DSM 3989 GN=EUBIFOR_00339 PE=4 SV=1 +---IQKEHVKVYPDTKELSELLQEMSQKLHESGFISdtKGFYEDVLLREKNYPTNLGSQMMVPHALF---TFADKTGIEVALLKKPLEHDGN---QVQLVFLLALEKkrNDEMNLLFQFFnQIVSHKKYMHELLQSEDSDAFIKNLY--- +>tr|N9VZS9|N9VZS9_9CLOT Uncharacterized protein OS=Hungatella hathewayi 12489931 GN=HMPREF1093_02380 PE=4 SV=1 +---FNTQCIKIFAKDagsadwngkAPFEIVIETLSRKFKEQDKIEtvEEYVDDVLSREVNYPTVIGESVMIPHPLM---TFAKETAVAAAILKPPVTICKK---AVKVIFLLAIEGrpNDDVSILFEFFkQVAMNENLVHTLYEAKDETDFLNRLI--- +>tr|A0A1V5MXF4|A0A1V5MXF4_9BACT Inner membrane protein YbaL OS=Planctomycetes bacterium ADurb.Bin412 GN=ybaL_2 PE=3 SV=1 +--QLAPHQIILRLKARSKEEAIRELVAAAVNSsGAEKrEMITKAVLEREQIESTGIGDGMAIPHARTE---AVEGIGICLGTSLKGIDYNAVDGKPVHILLLLVANESahdLYVHTLSSIASIFTDGPFRRDIIRSVDPPQVLARIKER- +>tr|A0A0W0AV70|A0A0W0AV70_AERSA PTS fructose transporter subunit IIA OS=Aeromonas salmonicida GN=VO69_19785 PE=4 SV=1 +--------------SLDKSLALRMLVDLLPAELVRdRPALEQAIAKREQIAATIIRPGLAMPHVICP---AIRQPALSLLSCAEPIEWGSALG-PVRIIILLAIPAglaPEQLRPLTRLARAMMDEVVSTALLHASSAPARQAIVI--- +>tr|A0A0D8R7V7|A0A0D8R7V7_PHOAN PTS fructose transporter subunit IIA OS=Photobacterium angustum GN=UA32_07720 PE=4 SV=1 +--------------DNNKAQLLATMTRSLVDEKvikVDdYQEVLAAIEKRESISATVMGNGIAMPHVMID---PIIQPAMV-ISCCQKMDWHSARG-NVSKVLMMVLPKplsRSVLMAFSRFSKQLLQDHYADALRQASDSNVIQALII--- +>tr|C9P8M0|C9P8M0_VIBME Putative PTS system nitrogen regulatory IIA component OS=Vibrio metschnikovii CIP 69.14 GN=VIB_002864 PE=4 SV=1 +--------------EfANQKDCL-HYI-----AQqanSAdEPALIRQLLAREAIAATTLPPSIALPHVISE---HISTPCLCVLTLAQAINWGSTQA-ETRFIIGLILPKrnpikKEEIMAATRLTRWLIESHHQQLLFQQPNEAHLKGLLL--- +>tr|I0IH15|I0IH15_PHYMF Putative transporter OS=Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01) GN=PSMK_23940 PE=4 SV=1 +-----TRATVLEAPEGAgYHGLIELASEVLAKKLPRtASFITEKFVESGNFGFAPMAYGAVLPHFRSA---DIEKPELVMIRSAKGFVTSFkadappgdagsdakkVG-STIHAMFLLVSPEahpGVHLRILAHLAGRLEKEDFMPAWLEADGEQTLKEILL--- +>tr|Q2S0A2|Q2S0A2_SALRD Cationic amino acid transporter OS=Salinibacter ruber (strain DSM 13855 / M31) GN=cat5 PE=4 SV=1 +-----AESDVIHLDEPVpYADVVEDVSGRLAEELGLsTETLEHGFLEGAPYSAVSVSHGAALPYCRLD---GISESKMVMVHCQSGICVDLedeieeldRS-EPVYAFFFLVSPKddeGEHLRTLATLANRTDEEQFLVEWRAAADEQEVKESLL--- +>tr|A0A0E9LRT7|A0A0E9LRT7_9BACT Uncharacterized protein OS=Geofilum rubicundum JCM 15548 GN=JCM15548_1390 PE=4 SV=1 +-----INARIVNLERKInFEALVEEVSEVFSTEMHVdKDVLVKEFYATSPIEPALVIPGVSILYAKND---GVDHPSLQIIICKNGIRKPVskgaisSE-DYIKVFFFLVNSSeesRQQLRMLSRLIDIVERDEFLEEMLRITSHREMKEFLL--- +>tr|A0A0D3LDN1|A0A0D3LDN1_9BACT Cationic amino acid transporter OS=Flammeovirgaceae bacterium 311 GN=D770_09315 PE=4 SV=1 +-----ERAIVLDRKGEeEdYEEVVQQAADALADHLGGdRHTIAEHLHDELKRWLKPQTSEVAIAPVLLE---GIEQPEMVIIRGKITVD----G-KSLNGLVALVDDEdssSRLVSLLSQLEAVVFQSGFVKDWKEAENAEELKAALK--- +>tr|Q1K1W9|Q1K1W9_DESAC Amino acid permease-associated region OS=Desulfuromonas acetoxidans DSM 684 GN=Dace_2765 PE=4 SV=1 +-----LRSQVIDLEEECsFEAALTIAAHKLEKVIPLtSDEIVEQIMVGTRIGATPVTRGVALPHFRST---AISQSEMVLMRARNGVRMARynpqtleeeGS-QRVKALFFLVSPDsnpSQHLRILARIAERVDEESFADQWLGAQQRNALKEALL--- +>tr|A0A120GBX0|A0A120GBX0_9SPHN Uncharacterized protein OS=Erythrobacter sp. AP23 GN=ASS64_10405 PE=4 SV=1 +-----GRAAFVDYGEGrFdSARLSRELSEIAQNEFGLdEKVAQ-SIFEGDRMDVRAIRPNMYLAYKIIP---DIDESQLAIFRFSGSATVAVtGA-RKVHTLMYLLLPEepvGLDLRIVGHLAEVAQSDNFEERWLAATQREEINRILA--- +>tr|V5WEE0|V5WEE0_9SPIO Uncharacterized protein OS=Salinispira pacifica GN=L21SP2_0753 PE=4 SV=1 +-----AEALTVDIDYReSVHGAFQMAGSRLAPKTGMtSEEITRLLEERESRFTTALTDFVSIPHILIP---GRDEIHLVLLRDREGLYFDDSH-PSIHAMFIIVGSEdrrDDHLKLIAGLAHVIQHKNFQDIWLSAESMNDLKDQLI--- +>tr|D0LSU2|D0LSU2_HALO1 Amino acid permease-associated region OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_4824 PE=4 SV=1 +-----AGAPLVHFAESAsFEQAARQAAEALADITELpTAELCEGFCTGSRTGATPVAHGVALPHLRIP---DLVRPVMVVVRAPEGVRIDIeditgvRQ-ETAHALFFLVSPTsdpAQHLRLLAAIASVADDDDFKAGFLAAKDGHGIRALLG--- +>tr|E3HB76|E3HB76_ILYPC Amino acid permease-associated region OS=Ilyobacter polytropus (strain DSM 2926 / CuHBu1) GN=Ilyop_0439 PE=4 SV=1 +-----KNAKILDLKGPvTLDELFDIEARHLTSVVDKpEHELIKLFNDREREFSTAITDFTAIPHIVVD---EKDLFYLMVVRCREGIRFNEKR-NSVKAVFLFISSPtlrKTHLRTLASIASLTREESYERKWMSAKNENYLRDMIL--- +>tr|A0A0D2J7S4|A0A0D2J7S4_9DELT Amino acid transporter OS=Dethiosulfatarculus sandiegensis GN=X474_09890 PE=4 SV=1 +-----RQGIILDIKEAtKPEALFTLLGKELAVHHLFnQETAANLLASREEKGSTVLLQGVAISDIPHP---DPDQIVLLAARLEPGVVLQKNQ-EQTRAFFLIVLGKnktNEYLQALAALAQITHHFDFMPNWLAGRDSDRLRDVLL--- +>tr|A0A0J7HLD9|A0A0J7HLD9_9BACT Amino acid permease OS=Chitinispirillum alkaliphilum GN=CHISP_3581 PE=4 SV=1 +-----INSAVIDLSSHhPgkitPALLEKVVPDCIANITGTePRSVKKHLFKMEQSRITAMEKVVI--LESTL---HVQDSHLLLVRFPSGFEADPqkypflcsCS-KPISALLVVVSKRqqmKKHLRIVGELLRRSDNSEFVAKWVTVPESDRLRELLL--- +>tr|A0A151EVM4|A0A151EVM4_9EURY Uncharacterized protein OS=Thermoplasmatales archaeon SG8-52-3 GN=AYK22_07150 PE=4 SV=1 +-----KGCDVIDIYKYlPPDKLSIVIAEKLSKRMNLsEKKLYRLLIKREKDSNIVVHPGIAVISHMIK---GRDKFEIIIIRSKKGFILSDNI-DPIHAFFIIIASTdkkSLYLHTLMWIIQIAEEADFGEEWINAKNEEELRDIFL--- +>tr|S7TGJ5|S7TGJ5_9DELT Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Desulfovibrio alkalitolerans DSM 16529 GN=dsat_1824 PE= +-----ERALVLDVTGGmDTNEMFSFVAERVEDVHGIsRHEVLRQLTVCCEDGIDVIVPEVAVAHVDVS---ErEGFLEMVAVRNVDGVHFPDG---RVMAFFLVLSSEderRFYIQAVAALAQIIADVEFEGKWRRAKNETSLRHLLL--- +>tr|A0A0D2GHU7|A0A0D2GHU7_9DELT Uncharacterized protein OS=Dethiosulfatarculus sandiegensis GN=X474_09895 PE=4 SV=1 +-----RGSKVLEFKKIsDTNQILASISLEAATEFGIeAQELALALKKRQKSQSTEMFPGVAITDALLP---GEGRLELVLVRLAPPVSLSPAQ-SPTRALFVILFTHdrrDAYLRSLAAIAQAAGNESFSRKWDQPKDPERLREILL--- +>tr|A0A101I350|A0A101I350_9BACT Amino acid permease-associated region OS=candidate division TA06 bacterium 34_109 GN=XE03_0756 PE=4 SV=1 +-----ENSKTFDIKGKyHFEDLFDLISSTTSSILGIeKEKIKENLLIREKESPTTLSNFVAIPHLLLE---GKGKFEIFFFRVKEGAVFPNE--EGIKMVVVIACTRderNFHLKSLAAIAQMVSSKKFEKEWLQARNENELKEVIL--- +>tr|U1Q4E6|U1Q4E6_9EURY Amino acid transporter OS=Halonotius sp. J07HN6 GN=J07HN6_02933 PE=4 SV=1 +-----AFPKQIDADRER--SLVSLAADIVRPD---dGRVIAVRFEEVPD--QAPLTDGLTdqssadrSFETRIE---GLE----------NAVGVDIeadeivSH-DTKHAIINFADKRa-VDTILAEHEPFVFGHGSWVIR-----------STGL--- +>tr|A0A1B6YAG8|A0A1B6YAG8_9BACT Amino acid transporter OS=Balneola sp. EhC07 GN=A8B79_02335 PE=4 SV=1 +-----SRSVVLDISDSeIsYRDIIKKASGNFATSFNMdEKQIFDLFWESQDIDTIPFAPSIAFNHIKLK---GDISSEIILARIPDSVFLKSdgfeslsknkqnEI-GNLRAIIFLISSSekpRQHLRILAHLAEIFDDNRFIKRWKKAKNEDEIREILL--- +>tr|A0A1M5DQQ4|A0A1M5DQQ4_9DELT Amino acid transporter OS=Desulfacinum infernum DSM 9756 GN=SAMN02745206_02493 PE=4 SV=1 +-----EASHVVDLGRIhGVEELLRELNPALLERGLDrPLGVEDLEGEEPRVKFVEIFEGIGVAEAAAS----rPDVFDVVLVRSRAGISFPGAA-APLHALFFFLVGSdekDFQLKAVAALAQVLQDPKFDSRWRRARNAQALKDLIV--- +>tr|A0A1L8N2F8|A0A1L8N2F8_9SPIO Uncharacterized protein OS=Treponema sp. CETP13 GN=BKP49_03455 PE=4 SV=1 +-----KQAKIIDITSShDYSSIIKVAAPDIASELHLsEDEIIEKFQEWYNSCESAVNDFLAIPHIVID---GTDTMFMYIIRSKEGIKFSETY-SSIKAVFLLCGTRddrVRHLKTIAAVASLSEQHEFKKKWLAAENTVCLKNFLV--- +>tr|A0A1L7S313|A0A1L7S313_9ZZZZ Amino acid permease OS=hydrothermal vent metagenome GN=MGWOODY_SVA2440 PE=4 SV=1 +-----ARAAVLSVPAGAdIAEAADRAATVLSDRIGLlRDRVTERFLETGSLWIQPSTeHPTATPVALFE---AIDEDHLVIVRAADGIRIPAawggSG-EWVNALFFVAGTAsnpGRSLRVAGELAGHLHTGAWAIG--VAQTEAEVKTALL--- +>tr|G5IIM2|G5IIM2_9CLOT Uncharacterized protein OS=Hungatella hathewayi WAL-18680 GN=HMPREF9473_03350 PE=4 SV=1 +--LFKPSLFFTDMEFESREAALSFMCGKLYEEGYVEEGFFESVIKREHIAPTAFEPGFAFSHGME---NNAYRTAVCTCILKNKISWGPY---QVKIVFLFALASsWNHtiIPVYNVMIDHLFQTSTIHKLAKIKDCGEFLDFL---- +>tr|D3AKB0|D3AKB0_9CLOT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Hungatella hathewayi DSM 13479 GN=CLOSTHATH_04053 PE=4 +-DLLTADRIQFTDDKLDWREAIRLASAPLIEDGSITQNYVRAMIDSIETtGPYIvLTPGVALPHARPS--KGAKKLAMAMLCSRERIYFNEE--KYANLLIILSSVdGHSHINALVHLSNMFGEEETLEKFMEAQTVEEVVELIHRY- +>tr|A0A174FLI5|A0A174FLI5_9CLOT Putative PRD domain-containing protein/PTS system L-ascorbate family, IIA component OS=Hungatella hathewayi GN=ulaC_2 PE=4 SV=1 +-DLLTADRIRFTDFVQDWRDAVRLAAAPLIEDGSITQNYVRAMIDSIETtGPYIiLTPGVALPHARPS--EGAKKLAMSMLCSKERIYFSDE--KYANLIIVLSSVdGHSHINALVHLSNIFGEEETLKQFMEAKNAEEVVELIRQY- +>tr|Q8KEQ6|Q8KEQ6_CHLTE PTS system, IIA component OS=Chlorobium tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) GN=CT0629 PE=4 SV=1 +---------LVELPDNDKSDALQFLATILEAVPSIPagSNIVEIVLEHEKNSNTSLGFGWACPHARVNFD---GDLCCAIGWSPAGIDYGIAGEPLVRLVVMFFVPEnqrNTYLKEVSTLARVLKSNPEFQNLEPIGDLDQVRNTLLD-- +>tr|A0A0P0GJ08|A0A0P0GJ08_9BACT Nitrogen regulatory protein OS=Candidatus Xiphinematobacter sp. Idaho Grape GN=ptsN_2 PE=4 SV=1 +---------LVELASSDKVASLEFLSNLIEAVPNVPpnIDVFRMVMEREVLANTAIGHAIACPHARVRQER--GSLLCTAGWSPVGIDYRAMDSVPVHLVCMYYVPSserGAFLKEMSALSHAVEKDSNMMALLKASSLEEVRGQLLG-- +>tr|A0A1V5ZR89|A0A1V5ZR89_9BACT PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC OS=Candidatus Hydrogenedentes bacterium ADurb.Bin179 G +--FLEPKNILCRMQATCWQDAITELACLLHRNegGFDLNEVVASCIRREEATSTVIAPLLALPHARVK---GLDRVLVAIGTLGAGILFASPDHGPVQVVILILTPHedpGLYLQVLAALTRNLGAPGAPDQLAEYTSADEIYHAFASN- +>tr|A0A1Y4ACH9|A0A1Y4ACH9_9ACTN Uncharacterized protein OS=Collinsella sp. An307 GN=B5F89_06450 PE=4 SV=1 +-SLFKPNLVFFGWECATPDEVFDHLAAELEARGLVAPTWREAVGARERVFPTGlktIGCGLALPHADAE---HTLAPFIAIARPATPVPFEPMGGigstVPADIVIALGFNHaDDQIGALQHLMGVFADEERAHAVLAAATPEELVAEL---- +>tr|A0A0N8GMY3|A0A0N8GMY3_9CHLR Uncharacterized protein OS=Ornatilinea apprima GN=ADN00_11530 PE=4 SV=1 +-DLLKTSHIVIHDGFDTWQEVVYAACQPLIRDHDIEERYLRATSRIIEEHGafMGLAPGMMLLHAKPT--EGVNQLCISLMKLRQPVIFHNAETGPVDIVAVLGAVdNHSHLTALFQLYSLVQNQAFMADLRAALSPADILRTI---- +>tr|A0A1V4MTC4|A0A1V4MTC4_9BACT Uncharacterized protein OS=Candidatus Aegiribacteria bacterium MLS_C GN=AVO35_07720 PE=4 SV=1 +-DALDPGLIEYRTDLSGKEGVLRRIAVLAAGSGKtgaaVEDRIFDALMERESLGSTGFGHGVAIPHCRTGSME---TFMAGLLVSSEGIDFDSIDGERVRIFPFVIGPesePRVYLRLLASIAQIFRHEDTRKAILSLRDPEEVRRLLREQ- +>tr|A0A0A8E4E8|A0A0A8E4E8_9GAMM PTS N-acetyl-D-glucosamine transporter OS=Francisella guangzhouensis GN=SD28_03970 PE=4 SV=1 +--LIDRKNIVLNLNIESKKRLIEFFANRLADAhPEVdEDKVISGIYQRERIGNTYIGKNIYIPHCRVE---GLSTTKIVIATLKNSYYDDTIS-EEIKIAVSVFFPYkisKIHMELLKQLALYLKSPQTQKYFEEADSADTLYKLIVK-- +>tr|A0A109UHJ1|A0A109UHJ1_9FIRM Uncharacterized protein OS=Erysipelothrix larvae GN=AOC36_10320 PE=4 SV=1 +-----EELFVYFDERTTKDDILKKLCNITMETNMCDEDLLSALKRRESMGDIVYGNGIALYHPDHL---LSEKTTLSVGVLKYPLEWQKNK--RVRFLFIVCGSKhdEKQLPIlFDKVSSIMRSKEALNQLLKTPDSQTFMNIFEN-- +>tr|F3AR55|F3AR55_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium 3_1_46FAA GN=HMPREF1025_00288 PE=4 SV=1 +------KMYLYIDQYMEKIELLNYLCDLCREKRFITEQEAEGIVGRENLVSTEIVEGIAMPHGLIEG-----SSFLVFALLKEPIIWGRT---SVKLVVMGCFQRgDERmKEELEYIFHLFLNLEDKNRLLSCKSAEEIERCMEV-- +>tr|U2U0B9|U2U0B9_9ACTN Phosphoenolpyruvate-dependent sugar PTS family porter, EIIA 2 component OS=Coriobacteriaceae bacterium BV3Ac1 GN=HMPREF1248_050 +---------TPSSEINHYTSVVSRMAKELVDCGLAQSGFHDLVLEREQYASTVYLNGVCIPHPMEP---VGNQDVVSVCVVEHGLTHGSK---EVCLIFLVCLRK-EHINmyqPIaRRLYALMRNRQLVNRLMSVVDGREFIQVFEWA- +>tr|A6DFY2|A6DFY2_9BACT PTS system, fructose-specific enzyme II, BC component OS=Lentisphaera araneosa HTCC2155 GN=LNTAR_18218 PE=4 SV=1 +---LFHDRVLLNVELRTKEDAIKMLCSELMKNGDITdlQATISLVLEREKLSTTGIGDEIAIPHCRSA---DVEYPMavFAYIREGESIDWDSVDGAGVRYIILLVSPlnePQMHIEAMKNITKSLMKPGFIDGLQVAAKRKTTLEWL---- +>tr|A0A212JD17|A0A212JD17_9FIRM Uncharacterized protein OS=uncultured Clostridiales bacterium GN=KL86CLO1_10873 PE=4 SV=1 +---IMEKQILLDFEAKSWQEAIRMSGELLKRGGYVNQNYIDKMVELVeENGPYIlFMPGFALAHASPD--DGASKLGVSLVRLKRPILFEGSD-IPIKYVVCLSITDkDSHISLMYQIYKSLTYEELFDNLSKCSTQTQIIELLRA-- +>tr|E2SHI6|E2SHI6_9FIRM PRD domain protein OS=Erysipelotrichaceae bacterium 3_1_53 GN=HMPREF0983_00435 PE=4 SV=1 +---LDPRLSMFQIRAADKNSLLHMLCESLIREGYGNQYIYESLLRREEVSGTAIGNLIAIPHPFPE---DILKSGIGIAVLKKPVLWDDE---KVQIVFLLCISTAenKNLeIIMEDIFEIAQNTELVMELKNTKDLPAFIQSIEK-- +>tr|A0A0C5VE93|A0A0C5VE93_9GAMM Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Gynuella sunshinyii YC6258 GN=YC6258_05592 PE=4 S +-NLITKEMVLLDIEAPTKQELIHHLCGQLFLVKRTdsPALLYQDVISREEKVSTFAGASMAIPHALS---HYISEPSLCFARVKSdEFTWDGAD-EAVRFVFMHVVPVQsSdlqrlresQSKVFSAIAELITLTDVQSMWAQTGDKDEILSSL---- +>tr|V5RLA3|V5RLA3_SPIAP PTS system fructose-specific IIA component OS=Spiroplasma apis B31 GN=fruB1 PE=4 SV=1 +--IINTEYIFLNIDIKSKEELFSHISNNAYKWEIVKsiPELIESFKERETLSSTALGGGFAIPHARNP---KIAKPAVFVYRFTKPIVWDDEN--EVEVAIVLLVPEgtGTYLDILSGIATKLMSEKNKDFLKNCQNKTEITSFLIS-- +>tr|B9Y2S2|B9Y2S2_9FIRM PRD domain protein OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_00097 PE=4 SV=1 +------PELYLEISASSRQEALMKQIEHIQKSLPLPADFYDSVAARERMGTTEYNNKIAIPHPLNP--E-QLPNFISICKLKKPVTWNA---KPVQIIFLVCINENqaLTRIFFDKISKIIQNSHLAFELLETRNYDEFMAKFS--- +>tr|A0A242DPJ4|A0A242DPJ4_9ENTE Uncharacterized protein OS=Enterococcus sp. 3C8_DIV0646 GN=A5876_003301 PE=4 SV=1 +--YLKPDFIRRTSEKLTWQQAVKFACHPLLEDQMITELFIQDCLDQIeeQGYAGYLGSQTCIPHTAPQ--NGVLKDGISLLIAAEPIAFPNG--KKIHFIYPLSFYDlTKHLKAVNQLADISNDSTFLNRLKESSDTKTAYQLIRQ-- +>tr|A0A1F7RXN0|A0A1F7RXN0_9BACT Uncharacterized protein OS=Candidatus Schekmanbacteria bacterium RBG_13_48_7 GN=A2161_08085 PE=4 SV=1 +-----------ELDTVDRIEAIKQLCEKLKThPGMLDyKKFCAEVLKRENLKSTAIGNFLAIPHARSE---SVNQIVLAVGKSSKALNFEIHNGSPINYIVLIGTPMdqvKGYLKLLARIVRMFKNNSDRETLLDSKTSTDIAAIFRA-- +>tr|A0A172Q5N8|A0A172Q5N8_9STRE Uncharacterized protein OS=Streptococcus pantholopis GN=A0O21_01450 PE=4 SV=1 +--------IYLNQNLLSRDDVYQFLAEKINkRTGLTKVNILSKFRLRESKGNIQIAEKVVFPHFIAD----KADNSFMILRLQKPIeEWSETI-SDISLIVAMTAKGDLTlaeKQTFAHFIRRLASKDFLEDLLTLNESN-LRTILNEE- +>tr|F8HEE3|F8HEE3_STRE5 Putative PTS system, EIIA component OS=Streptococcus salivarius (strain 57.I) GN=Ssal_01504 PE=4 SV=1 +--------VYANKEFQNQTEVYDFLAKKISLDKAEQEVIIQRFVNREQIGSIQISEKVIMPHFVAS----GYGNHIFLIRPKIPIsNWSTQI-GDVSIIIVIIFEENVSseiKSRLNNLIKNLMNPEFITLLEKESQNN-LINKLNEL- +>tr|A0A135YYH4|A0A135YYH4_9STRE Uncharacterized protein OS=Streptococcus pasteurianus GN=HMPREF3205_00371 PE=4 SV=1 +--------YVSNQNFNNRQEVYGYLASQIDSQTLSQQEIESKFLEREAMGNIEIAQGVVLPHFTNE----NVQDKIFIVRLSEPIlNWSKGI-AKVNIVIALVINSQTAfkiRPQIQNLIQHLIDEQFIELLMTGSQLE-IKNYLKQ-- +>tr|A0A1L8TEK6|A0A1L8TEK6_9ENTE Uncharacterized protein OS=Enterococcus gilvus GN=RV02_GL003649 PE=4 SV=1 +--------MFLNQELTNKAQLQRFIAMFAN--PEEADALIDLLQQREKVGNTMIAEHVILPHLESPK---IKQSQVLLIRLAAPVDLDEET-PEVQLVVTILLKSQESqeiKKQIAQFTRRLADEDFLEALLTVESDTRFNQLLEDN- +>tr|A0A239SXJ7|A0A239SXJ7_9STRE Putative PTS system, EIIA component OS=Streptococcus merionis GN=SAMEA4412692_01440 PE=4 SV=1 +--------FYSGESFPDRDSVYDFLVSKLCETAEGQLLLKDKLYYREEIGSIQIEEQVVLPHLQYE----GPWQGIIILRLKTPIkIWSEGI-DSVKLVICLVISEEMEenaKKKIRSFVRKLSRRDFFQFLLQKEESI-IEAYLEQG- +>tr|A0A239WLU2|A0A239WLU2_STRAI PTS system transporter subunit IIA OS=Streptococcus acidominimus GN=alsA1 PE=4 SV=1 +--------IYLEQPLTDKKSALKFLYDNCNiKDHISHNFFLENLEKREKQGSIEIAEGVILPHFEHEA---LTRTKIIIIRPLESIkNWSSTI-SKVDLVIALLYKAGDSln--EIKMLMKMLAKDSVIESLKNEEIEI-VNQIIRSK- +>tr|I6SA90|I6SA90_ENTHA PTS system, EIIA component OS=Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / +--------YVPPTVFHSRNEVYEWLAQQVDSEMGIkKEQIVQALLEREETGDIQIDEGVLLPHIENQ---LVKATKVIILPLEQRIaNWNPAI-QQVELILAVFLAPQEKietKRQIANFMRLLADEQVIKTLKEGKR------------ +>tr|C7T9J6|C7T9J6_LACRG PTS system transporter subunit IIA OS=Lactobacillus rhamnosus (strain ATCC 53103 / GG) GN=LRHM_0380 PE=4 SV=1 +--------VFTNVNLKTREEVYQFVVKQEFPSDIEnAKKLSRELVDREAQGNIQIAESIVLPHAECN---YIQRSKLLLIKTQRSIdTWSSDI-HDIKVVIVMLLKSDESrnvKMQFVDIMRQLGKDELIEQLLSEDD------------ +>tr|A0A091C344|A0A091C344_9ENTE Uncharacterized protein OS=Tetragenococcus muriaticus 3MR10-3 GN=TMU3MR103_0538 PE=4 SV=1 +--------VYPKKSFSSKDEVLTFLGKESSRLVGIpAMEFKEQLLKREEQGSIEIAPGILLPHFESP---SFTQSKVLLLSLNPEVkGWNSEI-NNVKLVIVILLKAEEErpvKQEIAAFTRKLADDKYLDELMKLGN------------ +>tr|A0A0E9GFD3|A0A0E9GFD3_CHLTH Multiphosphoryl transfer protein 1 OS=Chlamydia trachomatis GN=fryA_1 PE=4 SV=1 +--------QFFQQPFRSRQECYEFLVGQLGE---DeSTQFLHLLEERERLASVEIFPGVVMPHLESN---RLKESQIIILQLQDSIQWLNTT-RDVRLIILLAMKKDEEveiKRQLIAFVHQLADEEFIQALLENQT------------ +>tr|A0A033UEJ8|A0A033UEJ8_STAAU Uncharacterized protein OS=Staphylococcus aureus C0673 GN=V070_02364 PE=4 SV=1 +--------EIKTTN-IMYQDVIEEIGSQLKKdQYIQsESVFIEEVHEREQHGNIEIFPEVILPHIQSE---NILKTKIFLIKNETNLmNWHDR---SLKLIILLNLKPQEDqavLQDIQAFMRKLADEDFVESLL---------------- +>tr|V8BSF0|V8BSF0_9FIRM Uncharacterized protein OS=Ruminococcus lactaris CC59_002D GN=HMPREF1202_02161 PE=4 SV=1 +---LPASHIQLGVECQDWKEIVENMGRWMYEHGYVEKRYVASMIENtEKNGPYIvVLPGFAIPHDGQG--KGSIISGMYLVSLRRPIPFGVEKLDPVEFVCCFSAVDlKVHMKAFFSLISMFRNNTFKRKLRECKTSQDAAHLIEEY- +>tr|A0A0E2UEN6|A0A0E2UEN6_9STRE Transcription antiterminator OS=Streptococcus parauberis GN=SS13_contig00003-0102 PE=4 SV=1 +-------------PRETYQDYLKEMAKHLQETQLVDFEFEDRILKREEKQTTQFGNLVAFPHTINH---IDGNIILMLGLLEEPFKGTN---NLVEFIFMLAIPKtiegikeAELLELYDDIFRIAGSDSLKNELRKIDNEESFISFTKDR- +>tr|D4ELP3|D4ELP3_ENTFL HTH domain protein OS=Enterococcus faecalis S613 GN=HMPREF9376_01564 PE=4 SV=1 +-------------NTQGYRANIQKMIADLEAEKLVDPQFIERIFTREDQQTTIFESGIAFPHTINQ---ALPTIILSIGVFEESLVTPE---GKVDVILLLGIPEeltatveAELLQLYDRLFTIAGDERLRNELRKQRDVLAVKEWMQRK- +>tr|F2I6T5|F2I6T5_AERUA PRD domain protein OS=Aerococcus urinae (strain ACS-120-V-Col10a) GN=HMPREF9243_0306 PE=4 SV=1 +-------------QGESYEDLLRVMTDQVIEETGISSDFQQAIFDREAISDTVFDQGIAMPHTVVD---DFGQIILLIGQVEADIQEKG---RPIDLVFLLGIPSqtnqvmdELLINIYEAIFSVANNQDLKALLKTTHSLEDIQDILQGD- +>tr|A0A133Y3N6|A0A133Y3N6_9LACT PRD domain protein OS=Aerococcus christensenii GN=HMPREF3187_00356 PE=4 SV=1 +-------------EVSDYKSCLSIMCQQLYDKGLIAKNFAEKIFQREALSPTIFDNGVAMPHAMNN---HKNKTVLAIGQLHPALKTTA---YSVELIFMLAIPEleqettnEVLVQVYEFIFSAANHLNKRHKLLQTTSSKELLHIIQKG- +>tr|S1NS87|S1NS87_9ENTE Uncharacterized protein OS=Enterococcus columbae DSM 7374 = ATCC 51263 GN=I568_01556 PE=4 SV=1 +-------------SKASYEQILASLVQPYVLQGILDADFYVHLLEREKKSSTIYEQKIAFPHTLNS---SSQRVQLIVGIPKEAIQTAQ---GEIDLITLLAIPKeltkvaeDELMKVYGKIFELVSDAEKMQQLEQIQDEQSMWQFIDRK- +>tr|R2RCT9|R2RCT9_9ENTE Uncharacterized protein OS=Enterococcus raffinosus ATCC 49464 GN=UAK_04223 PE=4 SV=1 +-------------KQLAYEENLILLLEKLRVQQLIDDSFRDYILTKAQEESAIIDNGIAFPHGINR---QSEEILVTIGIYPDG--RST---EDIELIFMVAIPEnltlaveEELLSFYDTIFVISSSETLREQVKQIQTKEEYRQLLVNG- +>tr|E4KN50|E4KN50_9LACT PRD domain protein OS=Eremococcus coleocola ACS-139-V-Col8 GN=HMPREF9257_0027 PE=4 SV=1 +-------------TLDSYQAALSWMIQRFEESVTLDTSYRKTVMNQERLHATIFQNGLAFPHGINK---GTESIQMMLGILSKPILVNE---IEVKGIFMLVIGQeldpkteKDLVDIYDIVFRLANEQDFQTSIESFKGKEDFLHYLIER- +>tr|A0A242CAJ8|A0A242CAJ8_ENTFC Lichenan operon transcriptional antiterminator OS=Enterococcus faecium GN=A5801_001231 PE=4 SV=1 +-------------EKKTYQEYLNKLVAPLIRGYYVDEKFEKRILKRESQQSTFVNKEFAFPHTTNQ---LSQHIVLSVGLITDQGLAET---GGNGVIFLFAIPEemtaeveNELFELYDILFELIKM-GIDEFIELAPTQESFLKLIKSK- +>tr|A0A091C8I4|A0A091C8I4_9ENTE Transcriptional antiterminator OS=Tetragenococcus muriaticus 3MR10-3 GN=TMU3MR103_0138 PE=4 SV=1 +---ISKDGLIVEENAVSWHEALEQLSQPLIKQKVIEPRYLTALKQELPEIPPYIvfRHQLALPHTEPE--KGAYGVAISFGVFKQGILSTTE--DPIHFIVLLASNNkEKHIDALLEIMDLAGRDAVLSDLLACKDKDEVWRLLRL-- +>tr|A0A0J1F5D9|A0A0J1F5D9_9BACL Uncharacterized protein OS=Paenibacillus sp. VT-400 GN=EL84_01015 PE=4 SV=1 +----SPDDVFF-LNEDNPIDLLKKLTEL----GD-IQHLYTSIVEREKMSSTNIGNLVAMPHPFDC--GDNKKLRVLVAINKQKMLWGDQ---MAQIIFLFIPPKnqkVNNTKFFEEIYDVFKQTNMTEKLLHITNYDEFLEVWSS-- +>tr|A0A0J1ID34|A0A0J1ID34_BACCI Uncharacterized protein OS=Bacillus circulans GN=ABW02_18830 PE=4 SV=1 +----SENRFIL-LDENNKHDFLLRLTEK----VK-MEYLLDGILTREEMSSTEVGNYVAMPHPIAR--TENEETMIYIAINHKPIPWGKT---NVQLVFLILPSEvdrENHYKVFKQLYQLVKSKDKVQELIQTKDFHSFMEVLHT-- +>tr|A0A1G7A9D2|A0A1G7A9D2_9BACI Transcriptional antiterminator, BglG family OS=Bacillus aryabhattai B8W22 GN=SAMN04487777_10713 PE=4 SV=1 +----SPNDLYF-LDEETQKGLLKTLTNV----GG-VQHLYTSINEREKMSSTNIGNLVAMPHPFDY--GNNEKLRVLVAINKQKILWGDK---MAQIIFLFIPPKnqrVNNTKFFEEIHDVFKQTNMTEKLLNVANYDEFLEVWSS-- +>tr|A0A1L8SPV9|A0A1L8SPV9_9ENTE Uncharacterized protein OS=Enterococcus devriesei GN=RV00_GL000919 PE=4 SV=1 +----VtKIDYFTREKYTNKEKLLRGLLSS----IG-TPEMMESILDREEFSTTDISDGIAIPHPLLT--SNLEKTKIAVAIQEKPLDWGSQ---FVDLIIMIVPGKddqKMTSRIMEEIYHIIKDPELLETAKKATNLEEFNQIIEN-- +>tr|A0A087E9K5|A0A087E9K5_9BIFI Putative phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Bifidobacterium tsurumiense GN=BITS_1324 PE=4 +--------------AHTKAELLRKVVQELESRGLVTdsAEIITLLHERENLGSTLLTERLAIPHAQSE---AITKAAIVYVATEDPIaDWQSAS----RFIFTFLPeaPDRGDAYAIRDFFIRLADDDVAEALGE-CDEEQVLELL---- +>tr|A0A0R2FR01|A0A0R2FR01_9LACO Uncharacterized protein OS=Lactobacillus mali GN=IV36_GL002327 PE=4 SV=1 +--------------NTKKKELINDVVDYLLKKNLIYscDEVAKAINYRESLNSTIIAHNLAAPHAKSG---AIRQTILLFIKLKEgeFVtDWTEndksID----RFIFTLIPekCSLNDLQALKNFYIHLSKNNVMQLFCR-GKKDEIRKLL---- +>tr|D0DS12|D0DS12_LACFE Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Lactobacillus fermentum 28-3-CHN GN=HMPREF0513_00451 P +--------------SGTKEGFMDWEANFLAQEGIVGniQSVKQALKEREDAGSTLITEQLALPHFKID---EAKEAAIIFVQSAQPIaEWELgisID----RFLCIVVPdsKNKKDLEQLKNFFVWMASDGILEELSL-GSKEVVQGLI---- +>tr|A0A1S9CGZ6|A0A1S9CGZ6_9FIRM Uncharacterized protein OS=Epulopiscium sp. Nele67-Bin005 GN=ATN36_06420 PE=4 SV=1 +-------LFIPNLALSSKDEIIIYLTNLLEKENYVSEDFREGVFQREDLVSTDLEAGIAFPHSLK---NIAYKTSMVIAILTEPIIWNTK---KVKVVCMYANSCndIEQSNLFiKLFMSNIDNYTFVESLKKCKTYKQCQQTLLK-- +>tr|A0A1F5R4S6|A0A1F5R4S6_9BACT Uncharacterized protein OS=Candidatus Edwardsbacteria bacterium GWF2_54_11 GN=A2024_01540 PE=4 SV=1 +--YLKSDLIMLEAEVSDKKQLFEKAVDLAVEKGYVFdrEAFLESLWHREQDSPTTLGQGVAIPHSRSGA--ATDEVVIIYISLKRPIPgYVCDDRQPVKIVLMISAGEniQGYLKVLKLIGQAMGRESVRQQLKQADSPGKVMDVFH--- +>tr|A0A1R1HKQ7|A0A1R1HKQ7_PAEMA Transcriptional antiterminator BglG OS=Paenibacillus macerans GN=BK140_24000 PE=4 SV=1 +---FSEDLFYGALSAGTKQEAIHKMCSRIAETGITPPDFEELCLIRENLGSTAFGNLIALVHPIELC---SAVTKVGVGILKKQIDWAGV---PVKVVFVIAQAKsSEARDLLLLIQEIVHDSPLMIRLCEAESFAGFKRILL--- +>tr|A0A1Q8RET3|A0A1Q8RET3_9STRE Uncharacterized protein OS=Streptococcus sp. 'caviae' GN=BMI76_07885 PE=4 SV=1 +--FLTSDRIELEVEANDWQDSIYKVGEKLIAKGDITEDYLKVVISNIKENGPYvvISQGFAFPHAPFG--DYNRKTSMSLIRLKNMIYFDDEEHdnpqdiatMPVKYVCMLSITDrRKHLRAIFNLFNLLKDKDFREKMDSCQTAQEIHNLIYER- +>tr|A0A1Z1W5G6|A0A1Z1W5G6_9ACTN PTS sugar transporter OS=Streptomyces alboflavus GN=SMD44_01091 PE=4 SV=1 +--LLPVEAIRLDVAAEDWRAAIGAAGELLVATGSSTDAYTAEMIRTVVDSGPYivVAPGFAFAHARPS--PAVLRTGMAWVRLARPVEFGHETNDPVGLVVALAAEDaSAHTEAMASLARLLADPETTEALRVAPTPGAVRAILVG-- +>tr|E2SRN2|E2SRN2_9FIRM PRD domain protein OS=Erysipelotrichaceae bacterium 3_1_53 GN=HMPREF0983_03926 PE=4 SV=1 +---FDENLIFLEQSVENKEELLKQICDKLLKNGYVKEPFFSSVMQREREISTEIGSGVAIPHGNA---QYVNDTVIVYAGLQKTIPWGRDE--YVQHVFLPVISasNkNEverSIkNFYRRLIALIEHGEI-RRLLDMRDASEVIAHF---- +>tr|A0A1C6F0L2|A0A1C6F0L2_9FIRM Ascorbate-specific phosphotransferase enzyme IIA component OS=uncultured Eubacterium sp. GN=ulaC_2 PE=4 SV=1 +--LLSKERIELDYPAKDWEDAIRCAGKLLYDTKTVTEQYVEEMVNSVKKHGPYIvvCKGMALPHADCS--KGAIEEAASLVRLKTPIEFGSVYNDPVRYVIGMSIKSAEsINQAIYDMMKIFGDENNMNKFDSLPDEQAVLDMINS-- +>tr|G0EQW7|G0EQW7_BRAIP Putative Phosphotransferase system mannitol/fructose-specific IIA domain protein OS=Brachyspira intermedia (strain ATCC 51140 / +--YINNSYVILDLKADNKEEAISEMLIYSEANGLRiNiAQIIESMYKKEDIISSGLGYGVAFPHVRTN---QVEDNDIIFAVSKKGLNYSALDKKPVHLLTMFLTNknsNEKYLGLLSLFTKISRMSMYPVVLLESKTIEEFKEKLI--- +>tr|D5U9U1|D5U9U1_BRAM5 Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Brachyspira murdochii (strain ATCC 51284 / DSM 12563 / 56-150) GN=Bmu +--YIDNSYVILDLKASDKNEAISEMLIYSESKGLRiNiAQTIESMYKKEDIISSGLGYGVAFPHVRTN---EVEDNDIIFAVSKKGLNYFALDKKPVHLLTMFLTNknsNEKYLGLLSLFTKISRMSMYPVILLESKTEEEFKTKMK--- +>tr|C5EW03|C5EW03_9FIRM PRD domain protein OS=Clostridiales bacterium 1_7_47FAA GN=CBFG_05773 PE=4 SV=1 +-----PGLVAFGYSAADKMEAIRLGSDMLKKLGYVTDGFVDSVIKREMAVSTEVGFGFAIPHGSP---KFVRHSGIAVVRLDKTVLWHSGE--AVDTIFLIAACtDkrPqdmDELKGFYKiLAVLLDEEGPRKRFKSLNKAQDICNYINGK- +>tr|D5EHU9|D5EHU9_CORAD Sodium/hydrogen exchanger OS=Coraliomargarita akajimensis (strain DSM 45221 / IAM 15411 / JCM 23193 / KCTC 12865 / 04OKA010-24) +----------MELDCNNILDLYVKLGELASKQieGITAEQIHERLTDQSKVFPAFLGHGIAIPHIYCE---DLNYRVCFLAKLKQGIDIPG-QDEPIDFVFFLVSPRgdsDGHLATLAEIARLCRVDRSRKRIKSISSHEDAIAAVS--- +>tr|B5JJ49|B5JJ49_9BACT Transporter, CPA2 family OS=Verrucomicrobiae bacterium DG1235 GN=VDG1235_1849 PE=4 SV=1 +----------YRLaKLKDLDTIYHKLCDQAVLKdpRLDRPTLIEDLEEMARRRSPIFGDDVSALHLYSP---VLERTLCFLAWLETPVTSRS-GRTQVEFVFLLISPTndsEEPLPLLAQFVHLCHDHDALEAWAAKQETTDPI------- +>tr|A0A1V6G6R9|A0A1V6G6R9_9BACT K(+)/H(+) antiporter NhaP2 OS=Planctomycetes bacterium ADurb.Bin069 GN=nhaP2 PE=4 SV=1 +----------LDVHADSLEDLCGVLAAAAARRcpGISEQELAGDLRQKNHALLPYLGGGVALPHIYDA---AARRRVCIAARLARGLVLPD-AAEPIRLVFFVISPPddpKGHLATLAAISRFCVQERHRRALLEAAGAPAMKAYLR--- +>tr|A0A1Z9H9U2|A0A1Z9H9U2_9BACT Uncharacterized protein OS=Phycisphaera sp. TMED151 GN=CBD11_05060 PE=3 SV=1 +----------GPLQSNGIDGILHELMDRLVAArpDINREEILADLLSREQLNPTFVGDGVCIPHTHAR---GLDERVCVLGIAPEGTSYgP----HKVRLVFLLISPTgdpESHLATLAEIGRTCLDPSIRQALMEAQSGTKALQIIR--- +>tr|A0A1Y0L013|A0A1Y0L013_9MOLU PTS system, fructose-specific IIABC component OS=Spiroplasma clarkii GN=SCLARK_00694 PE=4 SV=1 +--------------TINRDQALKEIANLITDSEVINSNIVDGFIKREEIISTGIGNQIAIPHCQV---AGITDDYLVFLKVKKQIDWNSLDEKPVEYIFGIVTQenSDKHLEIIAFISNLLIDAAVKSKIINVKSQKDFVKLILD-- +>tr|C0QXL6|C0QXL6_BRAHW Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Brachyspira hyodysenteriae (strain ATCC 49526 / W +-DKITKEHVFEDLESKDKESLFKVLSEKIAPVASAsADAIFDAFKKREDEYTTNIGNGVAVPHGRIQ---GYGKTDIFVGFLKNEINYDSDSDekSPVKLIFAILSDldnPQDYLLNLSQIFFLVNQKEILDKVMATKSYDELASVLES-- +>tr|A0A1R7II73|A0A1R7II73_CLODI Transcription antiterminator OS=Clostridioides difficile GN=mtlA_2 PE=4 SV=1 +-----------ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDM---KYIKQSVLCFARLKTPIKIRNG--KDIKIILLLAYKKDDdrkvFRELFKEISNLTEDENMLDILSKCD------------- +>tr|A0A1L8TIS7|A0A1L8TIS7_9ENTE Uncharacterized protein OS=Enterococcus gilvus GN=RV02_GL001501 PE=4 SV=1 +---FDQRLISLEIEGENEEKVFENVAAHLEKLGFVNEGYLNGITARERQFPTGLitqHLNIALPHSDPE---YVDKPFVYIARLKDEVTVKQMGDSqkmGVKNLFFLGIKDpKGQVGLLQAFMELFMKEEFVAAFMQEQEEEKIYQMFVQ-- +>tr|R9J783|R9J783_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium 28-4 GN=C807_02470 PE=4 SV=1 +---IDPRLFERNHYENSIEQMIQYMAQKIIEMGFAPEEFTASVLEREAITHTSFDNKVAIPHSIVC---STEKNISFIIINEKPMKWGLFD---VQLIMMIGVNHNqrkDFKYIYSNLLERFEDQNIVKRLLNSRNYHEFIEILI--- +>tr|A0A1V6GDH7|A0A1V6GDH7_9BACT High-affinity Na(+)/H(+) antiporter NhaS3 OS=Verrucomicrobia bacterium ADurb.Bin070 GN=nhaS3_2 PE=4 SV=1 +--RLPADRIIARLRATTKEAAIAELIDLLHAQGGIRDraEASRAVLDREHAMSTGLGHGIATPHGRTD---AVDHVVCALGVSRPGLDFGGMDNRPVNLVLLTLFPasqNGRYVSFLAAALATLNDPALMSELVQCETPGAIHDVLMR-- +>tr|G5K553|G5K553_9STRE Phosphoenolpyruvate-dependent sugar PTS family porter, EIIA 2 OS=Streptococcus ictaluri 707-05 GN=STRIC_1941 PE=4 SV=1 +---LVDDNLYLRQQLLDKEAAISFLVEQGSTVNNASPRYLASIIAREAMGSTSVCTGVALPHAAPE---HVSQSQLMLMSLEEPILWGTN---WVSLIILIAIKEgeeERYKDALIYLYSKIDDRDFIDTLAKMEDEDLFMKTLFE-- +>tr|A0A1F9ZQC0|A0A1F9ZQC0_9FIRM Uncharacterized protein OS=Firmicutes bacterium GWF2_51_9 GN=A2Y20_10345 PE=4 SV=1 +---------YPSIRVKKSEECIRYLCGRLKEGSFVDDAFEASVLERESLIPTSIQTGVALPHATI---VHALKTSVAIATLQEAIEWGNQK---VSVVLLFAIAkeDIHYLNYFyAIISRFAMDEANIQRLAKCATFDAVIALLYE-- +>tr|A0A1G2Z853|A0A1G2Z853_9BACT Uncharacterized protein OS=Planctomycetes bacterium RBG_13_60_9 GN=A2Y76_01215 PE=4 SV=1 +--LFSPAGVICQTQETERDKILLDMLRLLADRRSIgDvEDAFDAVLARENDLPTIVAPGMAMPHARLE---ALDQIVVAVATSQEGVVYDPNRPdTRVKLIVLTLAPkaaPGAYLQAIGCLARICQDPATADLVASLRTPEQVWAFFDK-- +>tr|C0CWF4|C0CWF4_9FIRM HTH domain protein OS=[Clostridium asparagiforme] DSM 15981 GN=CLOSTASPAR_01320 PE=4 SV=1 +---FHKELYFRNVAQDSAQAYIKFMGGHCLEHGYVKEAFIQDVLLRESVSSTAFTDTLAVPHAIS---QFAEQSFICVVHNNMPIRWNHK---AIHFILLVGITQEemkYFKSSFDLIIELFNSTSRTIELLKTNTFEEFCGRM---- +>tr|U1Y1B4|U1Y1B4_9ACTN PRD domain protein OS=Atopobium sp. oral taxon 810 str. F0209 GN=HMPREF9069_00538 PE=4 SV=1 +---MSPELYLRNLHVSSATd-CIQRLGDHCIAEGVATPELIDDILTREHLSNTAFTDLLAVPHPIT---VSAQRSFACMLHNDEPIPWNgSR---KVNFVVMIGMTKGdtpFFQDILDLVIDLFLSPEKSQAALRTDSYEEFVRIL---- +>tr|A0A242JN64|A0A242JN64_ENTFC BglG family transcriptional antiterminator OS=Enterococcus faecium GN=A5839_001450 PE=4 SV=1 +--------IFPQLEWTDPVDILNFMGNVLVEHHYVEPEFVDSVLERDRHASTRVAPFVTIPHGNP---LYVKHSMISIATMKEPVLWHGE---QIRIVLLLAIKRKdlKHaefKKIFSVIHYLEKQPEQMAQLMQSNHPLEILTLLSSY- +>tr|A0A1U9YPI1|A0A1U9YPI1_9BACL Uncharacterized protein OS=Paenibacillus larvae subsp. pulvifaciens GN=B5S25_12745 PE=4 SV=1 +---LDKSMIKIHTEKVHGKYLLVEMAEQLREKGFVKEGYTESMLKREAMSSTSIGGGILLPHGEY---TLVNRSRVLLHKLKYPLTLENE---SIYFVFMLALKSEdlEGLeQLFYELGDIVDDPVFLEKLKAQHTPADLYDC----- +>tr|A8S5N7|A8S5N7_CLOBW Uncharacterized protein OS=Clostridium bolteae (strain ATCC BAA-613 / WAL 16351) GN=CLOBOL_07266 PE=4 SV=1 +--LFKKELFFPHTNFLSREEVIQFLCERMEASNYVDKAFHQEILYHEQVAPSAYR-NVALPHPLTADESLTRVSSIAVAINDHPIPWDTN---QVDFIFLLSLRGedRqLFKDVFTIISSFLQSDSNCRLLKSCDSFDTFVNLII--- +>tr|B9Y3X0|B9Y3X0_9FIRM PRD domain protein OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_00500 PE=4 SV=1 +--FFHPDLFFACRQFATHTDAIEVMCAAMTAGGYVDEDYRQQIDYHEKLSPSAYG-NIAIPHPLDNKA---KSSAIAVSVNPRPIQWGAN---QVNLVFMLSLMEkdKeQFSNIFDFIVHIMKDEETFRKMMEVTSFEEFTSLLV--- +>tr|G5HDZ6|G5HDZ6_9FIRM Uncharacterized protein OS=[Clostridium] citroniae WAL-17108 GN=HMPREF9469_00808 PE=4 SV=1 +--LLDESLVAVNVHARNCYDAIQLAGDLLKKKGYITQRHIDEMIRIKrKLGGyMVIDKGVALPHLLAP---ELSGPCMSVITLDKPVRFNHADNDPVDLIVMLLSNhNTAHIKVLEELVDLLGDAKKREAIRLSTSAYELLSII---- +>tr|A0A0K8JHQ7|A0A0K8JHQ7_9FIRM Uncharacterized protein OS=Propionispora sp. Iso2/2 GN=P22_2895 PE=4 SV=1 +-----ENLFEYFDMETDYLVCIQALTKRLKQENVITdeQKFYESVVQRENLYSTILDGMIAIPHPLES---FSKTTVVSVGILKEAVKYCG---KKVKLILLFAVNTreSEKLKMLfAMLEELLDSQDKLNELTKCTSYEEFMEKME--- +>tr|B0MD50|B0MD50_9FIRM PRD domain protein OS=Anaerostipes caccae DSM 14662 GN=ANACAC_01493 PE=4 SV=1 +--IISPHLIALDLYAGTWKDAVQLGGSLLMQEGLMTQEYIDSIVKNIEINGPYfvFWPHIALAHANASA--EFMPFSASLIRLKQPVFFGNEQNDPVKYIFTFIASDtsENDEKIL-SVINVASSPTLFQHLDEAKTPEEVYGIIHE-- +>tr|A0A1M5BX77|A0A1M5BX77_9CLOT Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Lactonifactor longoviformis DSM 17459 GN=SAMN02745158_03860 PE=4 SV=1 +--ILPEKNIILESGCRSKDEVIAYAAELVLGdcSGRAKEKLKQEIWERERLAYTGIGSHIALVHAESV---TVDCPVTACIRLKKYIDWAPGKAypplhKMVKLVFVFAVPKEegPETEVLKDMVRKLGKKETVDRLMRAEQSREIIGIF---- +>tr|A0A1T4LVV3|A0A1T4LVV3_9ACTN Transcriptional antiterminator OS=Coriobacteriaceae bacterium KH1P3 GN=SAMN06298223_0830 PE=4 SV=1 +--FISADDVQIASSSSGWEAAIGKAARPLVSRGSLEQRYVQRMVRAVKEYGTYmvMTPGTAYVHAGTN--DGINEDCTALLHLRSPVIFGDENAKPVRDVVVIGVKSSES-KALISIAKILSKETNRRRLEES-------------- +>tr|A0A1Y3SKR5|A0A1Y3SKR5_9FIRM Uncharacterized protein OS=Pseudoflavonifractor sp. An85 GN=B5G37_06605 PE=4 SV=1 +--YILPENIQILDHCSSWNDAIKIASAPLLQRGDIEQRYVDQMINAVNNYGTYmvLTPEVTYVHAGVN--DGIQRNCAAMLLLRTPILFGNFDRKRIRAVVVLGINNRQEDSELINLAYILGNEDNLQRLKDQ-------------- +>tr|A0A0T8I7K7|A0A0T8I7K7_STREE PTS system transporter subunit IIA OS=Streptococcus pneumoniae GN=ERS021354_07329 PE=4 SV=1 +-------MLAvlktaYQLKHakggrkpklsleDLLMATLQYVREXLEEREIVTPTYREALITREKSFPTGLDmeflgkdlPNVAIPHTDIV---HNLAEKVVVVRLEKPVTFHNMIApdKevEVSLLFFIINNsSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAE-- +>tr|A0A0R1F5Q6|A0A0R1F5Q6_9LACO LicABCH operon regulator OS=Lactobacillus coryniformis subsp. coryniformis KCTC 3167 = DSM 20001 GN=FD22_GL002407 PE=4 SV=1 +---VLKNSVLVHGQFSNKTEVIKQLLVQLKQ-----PEMLDNVMERERLSSTDVGTFTALPHPLIM--KTDCPFSMGIAVLDKPIQWGER---EVSLVILPLPNSNNHLEYERVfgiLQKIIVNEDNLAQLKRLQVPTDFMKLI---- +>tr|A0A1U3S5U3|A0A1U3S5U3_9MYCO Probable licABCH operon regulator OS=Mycobacterium abscessus subsp. massiliense GN=licR PE=4 SV=1 +---LSKDDILSkiqlsvEsnfklnhsnhilPIFEKSKEILDYH--HATL-----DGYIESAIDREKQSSTYIGKGIALPHGNPE--KVL-KSHMIIFKPSQPITWKQH---EVKLVFFLAMSKK-DLNINRKiIQSIAqLEEDDIHQLcllDDLQLKNTLYARF---- +>tr|A0A089XY57|A0A089XY57_9LACO Putative galactitol operon regulator (Transcriptional antiterminator), BglG family / PTS system, mannitol/fructose-specific IIA +---KPYIKVIFTHQQYSWTRLIAKISEPMIKSKIVNDAFFLALKKEYCDQPDYIllNRQIPLLHLDPD--VYPQQLGLTLLVSANPVKYGSA---KVNVVALLTTPNkTDHLPLLYQVKNMAKDTTFIHTLSQSANTKEAEKLVQK-- +>tr|A0A0E9E4S8|A0A0E9E4S8_CHLTH Probable licABCH operon regulator OS=Chlamydia trachomatis GN=licR_2 PE=4 SV=1 +---IKNENIVLAEDRLSWESILNQSSQALVNQKIISSDYNELLLQEYLDQPSYImlRQRILLPHLDPA--IVDQKLGVFITVLKQEITYHGK---KIHVVALLTTPDkTSHLPILYHINRMANDAEFIEELVKLEDVNEISKAIRN-- +>tr|F3L6J4|F3L6J4_STRPO PRD domain protein OS=Streptococcus porcinus str. Jelinkova 176 GN=STRPO_1597 PE=4 SV=1 +---LEESSIQIIDYRINWNDALKLVCHPLILDKKITDDYARALQEEYKEKPIHImlKSKLLLPHLDPY--IYQQKLGFSLLVLKDGILYNDQ---MIHFILLMTTPDkTSHLPFLLELRDLVAKENFSDLLLEANSADDIIKQIKY-- +>tr|A0A0R1NCD0|A0A0R1NCD0_9LACO Uncharacterized protein OS=Lactobacillus perolens DSM 12744 GN=FD09_GL000280 PE=4 SV=1 +---LPESLIFREQYFNGAQSCITWLCEQMNHQGYVSTTFKDDVLKREALSSTAFVKDIAVPHPLKPV---TAHTTIAFVLNHKPMQWGDS---YVRIIVLLGLSPNDHdefQVIFDALIAALSNADTVQKLLDTQSYTEIIDILRDS- +>tr|A0A1G1BBY7|A0A1G1BBY7_9BACT Uncharacterized protein OS=Melioribacter sp. GWF2_38_21 GN=A2X65_03855 PE=4 SV=1 +---LDKDSFHYSCEL-AESSYIAQMISQIRFEKNVDsEIIVQLLKSRESMMSTAIGNGISLPHPRVPLMVGRNKPLINFFFPIKQLDLKSIDGKPVHTIILLISQTiKQHLSLIAHLSFLLSNQAFRFALENRLDSREILDIIKK-- +>tr|A0A1W9RYS6|A0A1W9RYS6_9BACT Uncharacterized protein OS=candidate division Zixibacteria bacterium 4484_93 GN=B6D65_02580 PE=4 SV=1 +--LISRNVVLLGFSAGDKESAIRVLVDELTEQESLPdpRGALSALLEREKN-MTTGTEEVAFPHARLDSL---SDLYLLFAISPDGVDWGAIDRKKVHFIYLVLAPPsknSLMINLNAAFSELLSAKDARKILLSAKAPADVVDYIDS-- +>tr|A0A1V5FN42|A0A1V5FN42_9BACT PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC OS=candidate division BRC1 bacterium ADurb.BinA292 GN= +--LLNENHVLIGEAVQTMEEALRRMVRAFGAAVAPDqvDPLVHSLLAReEQH-PTVIDDRVCIPHMRMESL---DVFLLGLLVPEHPIPHPNPEQGPVALIFMILAPQtknTMMLQTLAAIARLLKSRETKQAILSVRSAPRLLRWIED-- +>tr|A0A177Q2L6|A0A177Q2L6_9PLAN Uncharacterized protein (Fragment) OS=Planctomycetaceae bacterium SCGC AG-212-D15 GN=AYO40_04405 PE=4 SV=1 +----LPEAILPDLRARSKAEAIRAMVESLGHALALSaeqiAATVTALLRREELGSTGMGRGVAVPHCSVP---FVAELVGGLALSREGVPFDSVDGRPAHFLVLMLAPAdrpGPRLKALERISQSLRQPrTYQGDLFRCRTVEEILAYAK--- +>tr|A0A1F8JM20|A0A1F8JM20_9BACT Uncharacterized protein OS=Chlamydiae bacterium RIFCSPHIGHO2_12_FULL_49_11 GN=A3F09_05690 PE=4 SV=1 +---LPPEQIFFFD-HGDRMEVIEKLCKGLLPEKLI-PAARSKILEREGEASTAIGKKVALPHASIDALDD---FILGVAVSpHAPItGWETFDMEPLHIVVMILAPSgrrESYLEILSEISKKLGQRRVVDEILKARTREEVAKIFH--- +>tr|B1ZSD8|B1ZSD8_OPITP Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Opitutus terrae (strain DSM 11246 / JCM 15787 / PB90-1) GN=Oter_2455 +---LRIGGIWRDVPAGSVRDVLSRVVEKLPGaTPTVRQFLAQRVQAPGGITWAAVGHGLALPHLRSHVALGREAGLLAMLFLRDPVSLDgeeAPDGVPVnRLLFFVAPTPRAHLELLAHLSAALSRGSLRQLVRDAAGDQEIFAAVAA-- +>tr|W0J5V3|W0J5V3_9BACT PTS sugar transporter subunit IIA OS=Opitutaceae bacterium TAV5 GN=OPIT5_19310 PE=4 SV=1 +---LRAGGIWRDVSADGLTGVLDQVVATLPGaTDPIRRLIVQRLHTRGGITFAPIGDGLAMPHPSARVALGRDSGTLALLLLREPLALSeeAPDGVPItRLFFFIAPSPRAHLDFLGKLCRLLGRGPLRAAVLRGAEDAEIHATLAE-- +>tr|A0A1G3ZGH0|A0A1G3ZGH0_9BACT PTS sugar transporter subunit IIA OS=Verrucomicrobia bacterium GWF2_62_7 GN=A2107_07520 PE=4 SV=1 +---LRAGGIWRDVPSSGAIEVLERVIASLSSiPQPVRALLAQRLRAKGGVNWAPIGGGFALPHFSTRVTLGRDAGVITLLLLRDALTLTepPSDGVPVtRLFFFIPPSPRAHLDTLARLSRAIAHGPLLGLVERSAPDEELFQTLAA-- +>tr|A0A1M6GML9|A0A1M6GML9_9DELT PTS IIA-like nitrogen-regulatory protein PtsN OS=Desulfatibacillum alkenivorans DSM 16219 GN=SAMN02745216_01050 PE=4 SV=1 +---MRRGGVFKDVEGGTVDEALTQAASL-SPvAGDHLQAFTQQLLERERLCSTGQGKGVAIPHVRSQTEDAGAEASVTTCFLKEPLDFNAIDGKPVtTLFLLISPSVDVHLRLLSRLAFCLRDDSFVEFLNQRPTSDDLLGKVQE-- +>tr|A0A0E2EKS0|A0A0E2EKS0_STRMG Putative transcriptional regulator OS=Streptococcus mutans 2ST1 GN=SMU29_02201 PE=4 SV=1 +---FSKDAFLQL-SDVSKEEVLKKMILSISKGekSHFADKMEELIYQRETMSSVVFSDTIAVPHPIKAV---GNRHHIAVAMIKDGLFWNQDY-PKMKLVFLTSMSiyDNDGLPELaSCIATLVDRPDIQQKMLTCQSFEQFKKLFLK-- +>tr|C2BGB6|C2BGB6_9FIRM PTS system, Lactose/Cellobiose specific IIB subunit OS=Anaerococcus lactolyticus ATCC 51172 GN=HMPREF0072_1386 PE=4 SV=1 +---FSEKNFLINKnP-CTKDEVLNLIYKSLAL-tPEMEEIFRDQTLLRENFGSIVFKTLVAIPHPISPI---KDKAEIFTVISKADISWGKDS-DKLKIVFYISPPgkNDPDFEKIiKVFTKILKDDSLIQALINIENFIDFKELILN-- +>tr|S0J0C7|S0J0C7_9ENTE Uncharacterized protein OS=Enterococcus saccharolyticus subsp. saccharolyticus ATCC 43076 GN=OMQ_02559 PE=4 SV=1 +---FAPELFLYLPGKSVKEQVIKELVARVEKIegSPLSERLMKQLQLRDTYSSVAFSSSLAVPHPIEPV---TQNAHVAVAIAPEGIFWDDEH-PAVQLVFLSLPDkaRQVQIDKInQMFVPILEDKEFGDSLVASQSFDEFMKKFVS-- +>tr|A0A175CQ94|A0A175CQ94_LEUGE Transcriptional antiterminator of lichenan operon, BglG family OS=Leuconostoc gelidum subsp. gasicomitatum GN=PB1A_1596 PE=4 SV +---TDSSRFKIWDeP-TYRKDVLDQLSDMITTDepSDFKQELLDQIAHRELLSAITFSDVIAVPHPARAM---SRVPKIAIGVIPSGLKWSTDY-PSIKLVFLLSPSylNNQGLTETtQTIVYLAENPEKQAELILAKDFSEFRKKFML-- +>tr|A0A011SIB4|A0A011SIB4_9LACT Transcriptional antiterminator of lichenan operon, BglG family OS=Alkalibacterium sp. AK22 GN=ADIAL_0783 PE=4 SV=1 +---FSPELFEVSDTVMDREEAVEVLIEKCTRVdeQIDADFLNRQLRLREGFSSVVFTKHIAVPHPVEGV---GDFSKVAVLVTPNGINWDGVS-EQVQLTILMVPDrfGHSHLDQVsKALLPVLENESYLEELIQAKDYPTFKETLLS-- +>tr|C0MDB9|C0MDB9_STRS7 Putative regulatory protein OS=Streptococcus equi subsp. zooepidemicus (strain H70) GN=SZO_06860 PE=4 SV=1 +---FSPKRFLYVKeK-LSKKALLLKMIACLDEAmdEAFVEAFYHQIVLRENYSSIVFGEVLAFPHPANPM---TYSEQVVVAVCQEPIDWDESH-RAVHFIFLLSPSkgRNSYLKYIsLSLVSFVNQAELQQALLEEPSYVQFVTLFTP-- +>tr|A0A160JSD9|A0A160JSD9_STRSU Transcription antiterminator BglG OS=Streptococcus suis GN=A6M16_09980 PE=4 SV=1 +---FAPHRIIYLEeG-CDREVALKQLVTTLNESiePDFVNRFIEQVNLRESYSPVVFGDRLAFPHPALPM---SYSEQIVVGIYKNAVDWGHGK--QVQFVFLLSPSkgRNAFLKYIsPCLVDFVQDRVLQERLLHHPNYKELIDIFIP-- +>tr|A0A178NVG3|A0A178NVG3_STALE Uncharacterized protein OS=Staphylococcus lentus GN=AXY34_05090 PE=4 SV=1 +---CSDYLFNYIEgS-IDKESIYNRLIQQLSIKedRDFECKLRNQLAYREELSTVLFSEAVAVPHTAQPV---GDYSSIAVAIIPEGIYWNDAY-QNIKVVIMLSPSkyNDNELKTIiDVIVNLIDSEENIQKLMECKTYQMFKDFMIN-- +>tr|A0A147IAR3|A0A147IAR3_STASC Uncharacterized protein OS=Staphylococcus sciuri GN=NS1R_14350 PE=4 SV=1 +---CSEHAFNYIEeA-TTKHQLYQLLIKQLSIKeePCFEEKLKRQLRYREELSTVVFSDEVAVPHTAQPV---GDYSSIAVALVPGGVYWNEQF-PNIKLIIMLSPSkyNDNELKTIiDIIVNLIDSDDKISELMNCKDYNSFKNYMIG-- +>tr|A0A139NCX0|A0A139NCX0_9STRE Transcriptional antiterminator of lichenan operon, BglG family OS=Streptococcus sp. DD10 GN=STRDD10_01410 PE=4 SV=1 +---FSEQHFQIY-HSGDKEVVLENMVQDLLVGdeEIRRDDFLALLAEREAIGTVVFSERIAVPHPCEPL---TRQAQVAVAICKEPLVWEEGR-EKIQLIFLLSPSiyNNEGFKVVtQKILAVTENEKIQEELVACEDFSTFLSLLKK-- +>tr|A0A1E9PP80|A0A1E9PP80_9LACT Uncharacterized protein OS=Aerococcus sp. HMSC062B07 GN=HMPREF2680_02985 PE=4 SV=1 +---FSEDRFIVTHkENINKEKMLSHMIALLEDNpqTNFNEMFLREIKIRETYGPIIFNNILAIPHPTKPL---TKDEKIVVAIIKKGLYWDSEN-PNIRFIFLLSPSitNNKNMRQVsNSLAKIIENKSLEDELLNINNYNDFKNIMLK-- +>tr|A0A1E8GN68|A0A1E8GN68_9LACT Transcription antiterminator BglG OS=Anthococcus sp. DF1 GN=BG261_02725 PE=4 SV=1 +---LSKEMFEIFEgENISKKCILDELLAKASQSerEDYKERMIEQINQRESMGQILFSETVAVPHPVLPV---GMTTKVAIGVIPKGFSWNDEY-ANVKFVFLISPSyiENENLISItKAIVKLVESENLQNDILQDITFEHFRNNFLR-- +>tr|A0A1S8KQE0|A0A1S8KQE0_9LACT Uncharacterized protein OS=Dolosigranulum pigrum GN=BWX42_09775 PE=4 SV=1 +---FRPELFSTKKNISTKEEVISQLVKVAVEYdpSINKTFLEGQLKLRESFGSVLFTKTLAIPHPIEGV---AEESKAAIILTPEGIKWSEDA-SEVLMTILLLPDryGGEDITELsKILTTLIEKPDKIELLSKVESFSEFIDNFKL-- +>tr|A0A242CYF6|A0A242CYF6_9ENTE Uncharacterized protein OS=Enterococcus sp. 3H8_DIV0648 GN=A5875_004465 PE=4 SV=1 +---VSEELFFVANEYADKTMILTEMLRRIEQKeeRVLKETFMKQIKLRESYSSVAFSNYLAVPHPIEPL---TNAAHVAIAIQPEGFYWDQAH-PNIQLVVLLSPDkfGHLNMDVIsQALEPILDNREFQQAILKCTSCQSFMEILKN-- +>tr|R9LTE6|R9LTE6_9FIRM Uncharacterized protein OS=Firmicutes bacterium M10-2 GN=C815_00211 PE=4 SV=1 +---FHPSLFFDHLPPMSRQEVLSVLSNRLWREGFVDETARDSFWQREQLGTTEIGNLLAVPHCMA---GTVVRPAIAVAVLEKPIVWEYG---MVQVVLMIAVSKEflkKENGFFLRLYQRLNTTMKIKEFINTRHLDLLMDAF---- +>tr|A0A1V6CQY0|A0A1V6CQY0_9BACT PTS system mannose-specific EIIBCA component OS=Planctomycetes bacterium ADurb.Bin126 GN=manP_2 PE=4 SV=1 +------RTVAVDLTAESKEQAIEMLVDALVDARQVPlarrDEVIAAVMRRERCGATYIGHGTAIPHAALC---GFRGLVGMLGVFPDGVPFGKAEDEGAKFLFLLLTPKEsyeVYLPILARIARFMNEPDHRRQLTQAATSADVVALLGQ-- +>tr|B9YAP5|B9YAP5_9FIRM PRD domain protein OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_02902 PE=4 SV=1 +---FDDQLFFCNHGLTTEVEILTFFDQLLQQRGVIDNQFMDSVRQRESLSSTAFFNRFAVPHSLEK---DALLTKVVYYYSDEPIRWYDS---RVNLVLLILSRSDdeQASKIYNLIFDILIDESCYKKMILCRSRQELMDFLEAN- +>tr|A0A0E3ZC50|A0A0E3ZC50_9FUSO Uncharacterized protein OS=Sneathia amnii GN=VC03_05505 PE=4 SV=1 +---------VHIDKTVTKDEVIRILCNMIKKHTNTTFPIYQKVLEREKLGFTEILNNIAIPHPMTKD---FNFNKVAIAVLDNKIKWDKK---FVNIVLLVCINDfdRYSEIIYSNIFNLFFSKEKLERLQKNPTYSNFMNLLKEG- +>tr|D1AWK7|D1AWK7_STRM9 PTS modulated transcriptional regulator, MtlR family OS=Streptobacillus moniliformis (strain ATCC 14647 / DSM 12112 / NCTC 1065 +---------IYLDEIKNKDEIIKLVSDKLMKIPNMNNDIEALIHKREKLGMTEISNEVAIPHPIGVI---EGVNVIGVCISKNPVKWINN---EVNIILFLCLDNknNKNEKIYEAFTKIVGNKEIINDILLNPTYDNFINILEHI- +>tr|A0A1B3XNV9|A0A1B3XNV9_9BACI Uncharacterized protein OS=Bacillus muralis GN=ABE28_011110 PE=4 SV=1 +---------------------gkFVWLQAIISQSHVviSPEGLIEAFKERERKGSFAIG-PIGILHSRT---SDVRALFVHIISLKEAVPWHAEngQKQSVDTLLLLAAPpdaPREHFPLLGELISGLLDDELAGAISSG-NKELALNA----- +>tr|A0A1M4YKT4|A0A1M4YKT4_9FIRM Transcriptional antiterminator, BglG family OS=Alkalibacter saccharofermentans DSM 14828 GN=SAMN02746064_01796 PE=4 SV=1 +------------------RD-elLKYIARYVSG-QDraRVEKLFEDIKRREDLMGTAIKSkNLALVHAKS---ESVDEVIAGVFRTKSPVAFTDAegNKELVDTVLMLLMGcdtPREHKEMLSQLSAMIVEaEDFIPMLRIG-DEEEIKEV----- +>tr|A0A1Q5P042|A0A1Q5P042_9BACI Uncharacterized protein OS=Domibacillus mangrovi GN=BLL40_14940 PE=4 SV=1 +------------------PVTIPSILNQIKDAQEisDLGKLSKDLEKREQQGGFVIG-DLAMVHAKS---EGVNNLLVVVFRMKELVLWPfADdeEQQSINTVLLLATPkeaPKEHIEMISEISSMLIEESFVSVLKES-TADVVKST----- +>tr|A0A243VZI1|A0A243VZI1_9ACTO Uncharacterized protein OS=Actinomyces sp. CtC 72 GN=BW737_13105 PE=4 SV=1 +----DPELFTRIPGGQDRDAALETAVSLLARAGAVGPEFLDQVKEREQLSTTAFASGAAIPHTIE---MTAARTAIAVCLADRSVDWDG---TPVRLVAMLCLSAdsrDAFGDVFDAVIKALVDPAKVARLAVADSYDAFVATM---- +>tr|A0A1R2E6V8|A0A1R2E6V8_CLODI Uncharacterized protein OS=Clostridioides difficile GN=BER30_002517 PE=4 SV=1 +---LDEDLVIFEPDIYFKKDLLEYVCSILINKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDS---STVNSTRFVFVKLKNPIDWGVG---NVNFIFMPVFQAN-DKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIF--- +>tr|A0A1A9YQS4|A0A1A9YQS4_GLOFF Uncharacterized protein OS=Glossina fuscipes fuscipes PE=4 SV=1 +---FTEATTFLKTAASDKTAVFKTLATALGNSKIVTneEQLIKALEKRETEGPTGVGDGLAIPHCSN--------------------------QKPVDVIFMITTPEkggEQHLQALAHLASFLGKSEVVAKIRAAKSFDDIITAFV--- +>tr|A0A1M5T5U3|A0A1M5T5U3_9FIRM Transcriptional antiterminator OS=Sporanaerobacter acetigenes DSM 13106 GN=SAMN02745180_00381 PE=4 SV=1 +--LFSEERFFTDLKNQDKYDLIDEIGEKLIAQNAIDKNTLNEVIKREHVSSTKIGNLVAIPHCVSS---SQSSSLIAVGLTEEPVVWDDE---KIQMIIFICFSEndTSSIKVFNYLYDLVRDEATIMNIVKNKSYDYLYEILFR-- +>tr|G1VPL8|G1VPL8_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium 2_2_44A GN=HMPREF9022_01949 PE=4 SV=1 +----KKELFFNCVEGKTRQEVIHNICCRMQKHYDKPIGMLEeKILERENLYPTDYGNFIAFPHPMEA---CTEETFISVSVLKDAVKWSEK---RVRIVFVISYGKgyveEEKIKNLNTLtFRLFSNREAVKRILENPVYETVIEQLI--- +>tr|A0A1L8SAJ9|A0A1L8SAJ9_ENTCA Uncharacterized protein OS=Enterococcus casseliflavus GN=RU99_GL001825 PE=4 SV=1 +--MMRPELIQLNKKARTWEEAFYLAANPLIERKIITRNYIDSIIQQTRSEGAYmvIFDQVALPHTVPE--AGAKKLGMGLTTLESEVYVLGT--IPVKYIFTLSALdSKQHLNAMTQFITLIESKDFFRELEKHECPETVYQWFAE-- +>tr|W7BU39|W7BU39_LISGR PTS modulated transcriptional regulator MtlR family protein OS=Listeria grayi FSL F6-1183 GN=LMUR_06729 PE=4 SV=1 +----------FHSDLSTREAILNEFSNKAAALGLCDDDFSASVLKREYRASTSIGRGMAIPHGNS---LSVRENAVFIIKNKRKVSWGVDE---VDTVILLVIhfSEgKKDGEFLGRLYNCMEKTDLIRNATGEESLEKIKKY----- +>tr|U2ILZ3|U2ILZ3_9STRE Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Streptococcus sobrinus W1703 GN=HMPREF1557_01383 PE=4 SV=1 +---LKSNYISVIPGVDTIEDVVKKSAQPLLNDKIITREYLNRVLRNLANhrQNYQIAPGILLPHASPE---GVNQIGLSFVILDKSIDTSYG---KIGLVIFLAAvDNTQHLLVMKDLLKLLSDANFIEEIRSQKSSEDILNLIQT-- +>tr|A0A0R1IEQ1|A0A0R1IEQ1_9LACO PRD domain protein OS=Lactobacillus paralimentarius DSM 13961 = JCM 10707 GN=FC97_GL000087 PE=4 SV=1 +RELLTLRNIKImhVNKNTTWLDVLHTGCRMLSQQEIIEPRYENEIVKLIKKYGPYmlISDDIFMAHASPK--NGSNRVGISMVLLDNPVIIAEKNQkVNVSCMFVLSPGsNHEHDRVLEELISIVRNTEKINKILVSKDKLEIRKLM---- +>tr|A0A087Q9U8|A0A087Q9U8_LACGS Putative PRD domain protein OS=Lactobacillus gasseri SV-16A-US GN=HMPREF5175_01914 PE=4 SV=1 +MDLLNRSSIKIidNLMnGTDLNPIIKELSEELEKNNIVTSGYCDDILSLIDKYGPYmlLSSDTFLAHAAPS--KHTRKIGIEIGILKRPIKISVNNIeEKIKCVIVLVPGfHQEHDKALAQLINIITNRRLYDQILSETDTDKMYKLI---- +>tr|A0A0R2AMB6|A0A0R2AMB6_9LACO Uncharacterized protein OS=Lactobacillus agilis DSM 20509 GN=FC14_GL001451 PE=4 SV=1 +VDLMSQNDIIF--SkESTIQRVIEEGTSVLERKGVVTKDYLSEINRLISQYGNYmhLSNGVFLAHAEPQ--DGVLKTGLSLVISKKGIPLSDG--SVVKLVFVLAPGtSEEHSKALSEIVSIARSKEKVQAIVDIGDRNEIYQYL---- +>tr|A0A1F9VF44|A0A1F9VF44_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RBG_16_66_12 GN=A2V88_03045 PE=4 SV=1 +--------VEANLPTGDRRTAVRHLLAKLKALrpSLDAEGAFTAVWDRELKFASAVGRGVMVPHARL---SGLGEPLIAVGRYAKPAPFPTPDGVAVRLVFLVLSPAEtpiIQLKILQRIASLVTNENIRRKLWRAKTDEALFTLLST-- +>tr|A0A1G3KQX9|A0A1G3KQX9_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWB1_36_13 GN=A2Y41_13700 PE=4 SV=1 +--LIQEDSLIFNLKASTKNEAILEIIQTFSPDKKKNQEIYDAVIERENIGSTlIENTGVVFPHVRSA---ALDDFYIGIGISEKGIETENNLGGMEKafLFLVVAAHplkNQLMLNIRSSLLKLLKTDpALFE---KLKKPAGRDEFLS--- +>tr|A0A1G2ZEK4|A0A1G2ZEK4_9BACT Uncharacterized protein OS=Planctomycetes bacterium RBG_16_43_13 GN=A2W23_06755 PE=4 SV=1 +--LLDTRLIKCGLEAQDKDSALTELVKLLIGydATISEQGILSALADREKLGPFSLGKGIGFPHARTD---SVKDLLIVMGTSQNGIDFRSPDGQKAKviILFIIPKKhSNLYLHAFAAFLNFFSLEvNLLKV-ASAKTPAEVIGYIE--- +>tr|A0A1Q8EAX0|A0A1Q8EAX0_9STRE Uncharacterized protein OS=Streptococcus cuniculi GN=BU202_01220 PE=4 SV=1 +----DETFFYPQLKVETATEAITVMVDKLKRYSIVDDSFLESCLQREACSATSFDYSLAIPHPLVL---NSRQSVISIAHLDHPIEWGGS---RVEMVMLLALNeaDREFMTIfFDWLARIISDQDSIRTLVSIDNRDQFIQYIVQ-- +>tr|A0A0H0YJE9|A0A0H0YJE9_LACCA Transcriptional antiterminator OS=Lactobacillus casei GN=AAW28_13850 PE=4 SV=1 +--LLVPSLFFQQSTPTDYRGLLTTVTATMAE--YCgQADYAASVLQREDFLPTIYDNGIAIPHPLSF---NAKKNAVAVILLPNGATNTA---RSVQLVWLIALKQDqlpLHRTLTMQLAALMQKADVINKLVQQTEFSSFHQILRT-- +>tr|A0A0R1NBK3|A0A0R1NBK3_9LACO Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Lactobacillus rapi DSM 19907 = JCM 15042 GN=FD12_GL001 +-----EDSVIFAEKQYTKRELFESVCNQLAKSRVLSdaSEVVKQLLEREEISDTRIDDLIAMPHCES---SAVIFPKIILVNCRKfPIFWDHDV-MVTGIVFLFIPtSDSDEIKEIPHFVKKLADPNVTKELFESNNRTQFI------- +>tr|A0A0R2LQZ5|A0A0R2LQZ5_9LACO Uncharacterized protein OS=Lactobacillus paucivorans GN=IV54_GL000501 PE=4 SV=1 +-----GTQAILVKRHLTKQQLFKRVCQALGDQAVITepEVAVAALEERERLAETLITERVAMPHCQS---AVIKQSKVVLVNCKRfPITWDDVGHQVEGLVILLLaKdAPQDQLQRITDFVRQLADSDVADSLFEEEPTAADS------- +>tr|A0A0R1QB96|A0A0R1QB96_9LACO Uncharacterized protein OS=Lactobacillus nagelii DSM 13675 GN=FD45_GL000569 PE=4 SV=1 +---LSEEHFQISRSFADKKSFIEQRGNDLLKTGYIEADFLGDVLKRESMSSTNMLNGVAIPHSLQ---IGANRSIIDITIFPSGVVWDQNA-APVEIVVLSCIKASDqaiFGDFMDHLVKITSNSKLFNRLKESRSFNDFLHELR--- +>tr|A0A1E8VUI2|A0A1E8VUI2_9ACTN Uncharacterized protein OS=Olsenella sp. HMSC062G07 GN=HMPREF2826_04895 PE=4 SV=1 +---LNSDGVRIENGPLRWKDAILLASERLQKGGFVQESYVEKAISNVEEYGSYivVNQGIALAHAGSE--DGVEKDGISLLICPDGIQFDDID-DAVHLMFFFSQtKGgEAYLGLFQEVIKLGNNRIDLASIRFSKSSEEAYQRIV--- +>tr|A0A0V8CQL1|A0A0V8CQL1_LACLL Uncharacterized protein OS=Lactococcus lactis subsp. lactis GN=KF282_1792 PE=4 SV=1 +----NPSHFMVIEEKKSKETVLEEISNILYKDKSVTIDFFNDLLAREALSSIVINDSIALPHPLN---DSVIKSTIFVAVVPRGLEWDENT--NVKFIFLLVIKSNevEELqNVYETLLDFIYSNDKQESLIKNPNYNNLLNIFT--- +>tr|E3GMB9|E3GMB9_EUBLK Transcriptional antiterminator OS=Eubacterium limosum (strain KIST612) GN=ELI_1876 PE=4 SV=1 +--HLTENDITIIDHIEDWSKALHLCSQVLIGKNVINTAYCEEIENSIHLYGAHfiLRNSMAIPHAGEK--AGVLGSGMHVLYIKDGVIFPDN--LKVRMIFFIASKEkELLINTVMRINAFSNDLNFYDVFDQKiKEGRCLAAYLKN-- +>tr|D1AKT2|D1AKT2_SEBTE Transcriptional antiterminator, BglG OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_0213 PE=4 SV=1 +--FITKEEVSILDSVKDWQESIKTAGNLLLKNKKITEKYIDEIIHITETFGAHfvFQNEVAIPHGDAS--KNVNISSVSILKLRKAVLFPGE--KKVSLIFFISAKRkKDHVKSIEDIIKLMKNTEFIEKTNTVKNTEEFLELIKL-- +>tr|A0A1F3IV10|A0A1F3IV10_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWF2_33_16 GN=A2W99_01860 PE=4 SV=1 +--FFSPENIEFYGDPINTDQLVLKLLQNLALnYGIGNvVSLFNNIYQNNRTKLLTNNCKPKIVTFPLH---NTDKTLIAIAIAKNNTD--NPPSESSELLIIITYPkanPDIILKVKKAFNDYFINPDFINEILQSKNSKSIWNIFDQ-- +>tr|A0A1E7E268|A0A1E7E268_LISMN PTS fructose transporter subunit IIA OS=Listeria monocytogenes GN=AJL15_11565 PE=4 SV=1 +----HEDLFLTNYEYDQKYNAIDFLSEYCISKGYVPTSFTEKLFSREQLFSTAIPTGIALPHPIK---NVAIKSGIFICIMKKPITWDNH---KVSLIMIPMIEelDGTEAPLINDFLSlIASNKSYVEQISKCSTYHECVELLQ--- +>tr|A0A1E7E129|A0A1E7E129_LISMN PTS fructose transporter subunit IIA OS=Listeria monocytogenes GN=AJL08_00810 PE=4 SV=1 +----HEELFLTDYAYEQKYNAIEFLSQYCIDKGYVPERFTEKLYNREQLFSTAIPTGIALPHPIK---NVAHKSGIFICILKKPCAWDTH---KVSLIMIPMIEelDGTEAPLINDFLSlIASNKSYVEQISACSTYRECVELLQ--- +>tr|A0A0E2VCH3|A0A0E2VCH3_OENOE PTS fructose transporter subunit IIA OS=Oenococcus oeni GN=EL27_07185 PE=4 SV=1 +--------LFRELNSVDKITSIKELSSLLSENRLLKekQDFLRLIYEREKQGNTLIAPRIAMPHAEG---ISVRKTGMAIGKSTKLINWNNN--QFVEMILLVSINPADeiNNEKLIRIIRELGKEEKTVHLIDSTKTNILR------- +>tr|A0A0R1R905|A0A0R1R905_9LACO Uncharacterized protein OS=Lactobacillus rossiae DSM 15814 GN=FD35_GL001081 PE=4 SV=1 +--------FFMSLSSSDsSLDAFQTMAQRLSQLQRVSdvDAFTDLIVKREAQGLTMIAPQILMPHAVG---SVVLKNTVLVGLFPTLQHWNRG--LSVRLIVMLATPNAAaaqNDPQLMTLLTKLADEQVTEKLVAQKTVSQVQ------- +>tr|A0A1Q3RJU6|A0A1Q3RJU6_9FIRM Uncharacterized protein OS=Clostridiales bacterium 38-18 GN=BGO41_12430 PE=4 SV=1 +--YFSEEHYFREVDLETKEEVIEYMLQSMSIE---DVDTRRKILQREKTSSTERGNSVAIPHTNYL---FIESPRIAICLLKKPIIWHRE---YCQLVFLVLNGKqEkEPFIALSIAKAATGNIQFVYDMIRTKNFKEAHEVLE--- +>tr|A0A1T4K9F4|A0A1T4K9F4_9BACT Transcriptional antiterminator OS=Anaerorhabdus furcosa GN=SAMN02745191_0410 PE=4 SV=1 +--CLDKNCCLFDVDAQTSEKVITKLSKQMIENAKITNGFEQMVLQREEISSTERGNNVVIAHSLFP---ASEKTIIGVAILKHPITWGQE---NAQLVFMVSNGNnEeQMFTVLQWLQLLVQDFEFVHECLNAKNFEEIRLAIE--- +>tr|E3FEW0|E3FEW0_STIAD Transcriptional regulator OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STAUR_1137 PE=4 SV=1 +--LLTPERLVLQLSCANLDDALDVAAGRLAPAcpGMGAGELAARLRQREEDVSSAVGNGVAVPRVFQTE---R-PALATLVTLARPLQVETPDGLPLRLVVALMGPerGRSSLMQLAHVARLAN-QGLADQLAGAQHPHEVFQRLQT-- +>tr|B1C8U8|B1C8U8_9FIRM PRD domain protein OS=Anaerofustis stercorihominis DSM 17244 GN=ANASTE_01716 PE=4 SV=1 +--SINPSLIKITDDITSWEEVLRQGGDLLINAGYASKDFSDDLIKSANLNGPYfvIRKGVGLAHALSK--DSNYESAISLTVLKNGVKFNHPYNDPVKLLFSLVIKDsKSYLNIFNDVLKLSTNKDFTHGVINAKSEKEVYDIIVK-- +>tr|A0A1C6HDQ3|A0A1C6HDQ3_9CLOT Probable licABCH operon regulator OS=uncultured Clostridium sp. GN=licR PE=4 SV=1 +--LLRPSGILTGVHSCSKNEILKKLCTLMETSGNVTNAFYNTVLYRESLCSTYIGNGLVFTHGDSE---QVHQSALSIALLDTPIPWDDAE---VDLIFVYAFNLedleRNSIkmdDFFSIFIDITNENDRMNELRKQQDPDAFYNTFL--- +>tr|A0A0G9FFJ3|A0A0G9FFJ3_LACPN Sorbitol operon transcription regulator OS=Lactobacillus plantarum GN=IV39_GL000235 PE=4 SV=1 +----------------TYVTGVKKLINQEIQHGQLTPDFMQAWLNREQQSSSIFGDGVALPHVIDK--SGLNRILVTVGVFEKPVVFDNQ---KVNVVFLVAIPYkldATLSKILAQVYDLIrsitANSNIYNNLKNYDENQGLN------- +>tr|A0A0R1Y5T3|A0A0R1Y5T3_9LACO Sorbitol operon transcription regulator OS=Lactobacillus composti DSM 18527 = JCM 14202 GN=FC83_GL002145 PE=4 SV=1 +----------------DYFKGSEWLIQQEIELGQVNESFVDRWYKREQKKLNIYENGVAIPHVIDD--SGAPRVLLTIGYYEREITYAKR---KVQLVFLIGIPQkvdGQLSKALSQVYDFIfsvsQNQRIYHNLLHFDNKRPLA------- +>tr|W0HMW3|W0HMW3_9ENTR PTS modulated transcriptional antiterminator OS=Sodalis praecaptivus GN=manR PE=4 SV=1 +-----PEMTFAIDDSVDKETVLTTLCHAAVRQGLIDPGYLQSLLAREKISSTEIAPGVVLTHGDPA---LVKRNFISLTRLAAPACWREG--RACDVIVLVAFKKaadgkiDSsIAGFYSMLARLVDNECAMKSLRQCKTPGELYRYFIS-- +>tr|A0A0R2C500|A0A0R2C500_9LACO Uncharacterized protein OS=Lactobacillus thailandensis DSM 22698 = JCM 13996 GN=FD19_GL001743 PE=4 SV=1 +---LSRDLFFNHMQFKTKQEALDFGAQQFESQGYTDDKFIHEILKREKLAATNFG-NVAIPHTMRM---KAKHTVMLVIMNDKPIKWSAES--SCRLIIMIAVSNKaVHvfGELLQVMISALSIKHNVELLLACDDYDQFATQF---- +>tr|B9XR60|B9XR60_PEDPL Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Pedosphaera parvula (strain Ellin514) GN=Cflav_PD0708 PE=4 SV=1 +-----EGLIVPDLKARDMAGVILELSNAFQKHDPVWnaQRLNQAALGREEQMSTAMNFLTAFPHVRSK---DCPKMQFALGRASEPMEWGRPGSLKVQFVFLNAIPATealGYLKLLSGASKLGKEAALLEQFKAAATARELYQLLQK-- +>tr|B1ZR78|B1ZR78_OPITP Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Opitutus terrae (strain DSM 11246 / JCM 15787 / PB90-1) GN=Oter_1280 +-----DRLCVPACRGRDATSVLLELSLAFAEAGVVSdsLSLYNAALNEYFLTDRDVLGSVAYPVCRLS---AIEAPVFAVARSREPYTWRD-GFSSVRWVFLILTPQVqsrRLSRLLAAISELAHDDAALASLALAGNRDELLERLRT-- +>tr|A0A0R1JB71|A0A0R1JB71_9LACO Uncharacterized protein OS=Lactobacillus tucceti DSM 20183 GN=FC72_GL001796 PE=4 SV=1 +--KLNKNNVFANLPMSNYdeVKALSLISYAVAKkLNISEQEVKSSFLSREATCSSSIGEKIAIPKASA---SEVSEPQIFAFTSEMPIDWVSVDDKPVNIFLAIVAKS---------------------------------------- +>tr|A0A0R1RLD4|A0A0R1RLD4_9LACO Uncharacterized protein OS=Lactobacillus rossiae DSM 15814 GN=FD35_GL002530 PE=4 SV=1 +--KLFRKNVYTDVELADNneIAALKLIAHTAADkLGVDEQELKSGLIVREAMSTSAM-GDIAVPHANA---SDIANPTVLAFTFAEPIIWGEAPTHSVDTVIALIMPR---------------------------------------- +>tr|A0A0R2C5P0|A0A0R2C5P0_9LACO Uncharacterized protein OS=Lactobacillus thailandensis DSM 22698 = JCM 13996 GN=FD19_GL001337 PE=4 SV=1 +--LLKKKNVVANVALDENneLAALKAIANRVAGkLDLAEQELKSGFFASGAQDAVIIGDEAVILRATS---STLTHPEAVVLSFDSPVQWGD-DNSSVDIAIAIVLPV---------------------------------------- +>tr|F0H1Z7|F0H1Z7_9FIRM Glycerol kinase OS=Anaerococcus hydrogenalis ACS-025-V-Sch4 GN=glpK PE=3 SV=1 +--IIKKDNIKFTDLKLDWKKALYLSAKPLLDDGSIKEGFIENIIENiEKNGPYiNLGKGIAIAHTKDS--SFVNEDSLSLLRLSCPVIVSNDEKNPIYNLFTLATTGsDKHLNYLSSLTKNLSDESILKEFEDATSRSHIHKLLNN-- +>tr|C4V0J7|C4V0J7_9FIRM PRD domain protein OS=Selenomonas flueggei ATCC 43531 GN=HMPREF0908_0041 PE=4 SV=1 +--------------AASIEQLANAAAHLLLA--EDAaaKDFADELLRRERIAPTWAa-PQMILLHGCFA---RQERARFGVMHLAHPLPYGG----gAVQTALVMLVPageAEMERQILGHVAAQIADRPTFADILARGDAAGIRRELEY-- +>tr|U2URG9|U2URG9_9FIRM PRD domain protein OS=Mitsuokella sp. oral taxon 131 str. W9106 GN=HMPREF1985_00647 PE=4 SV=1 +--------------VSDAKRLCMIAAEQICT--DRTarNSIMDAFLQRESKGSTIIkGHGIMVLHARTK---ASPAPRAGVLRLSAPFVSES----gIVRTVLVLLAVmeKEESAEAVGAISTGLFERDGFLSVLHDGEHGAVFQAISD-- +>tr|A0A075K8M0|A0A075K8M0_9FIRM PTS modulated transcriptional regulator, MtlR family OS=Pelosinus sp. UFO1 GN=UFO1_0939 PE=4 SV=1 +--------------SKTIEEMIQGVSSLLGT--NDEmvSQLAAALQDREEKGGTFItGHGFVLLHCRTE---AVKKLHFGVVQNAKQIYAMNGKGQkeEVTLGIIMIAPeksSEHAIETISHLSKMLVERPDFIRLLQEGAEKDAVREVSN-- +>tr|A0A173ZN06|A0A173ZN06_9FIRM Probable licABCH operon regulator OS=Mitsuokella jalaludinii GN=licR_1 PE=4 SV=1 +--------------TPHIEDICRAAGRAVSE--DVAaqQGIAEALLARESKGETILrGNAMVLLHARTD---FAPGLHFGILHLEQPMLYPEQD--geAVRTAVVMLAPqesSCEALETIGTVSAALLERWGLIALLNEGNQDAIYQELEH-- +>tr|A0A023X0C3|A0A023X0C3_9ACTN PRD domain OS=Rubrobacter radiotolerans GN=RradSPS_0353 PE=4 SV=1 +--------------GGSEDEAARLMCRSLVARGLAAdeAGLAQALTERARRGGIGIpGTAVALFHARER---SVERPSFSVHELDEPIMLEGMDGErmAVRRALLMVAPldlSSVGLETVSEISAAMVERPAVRETFERGDEENVLDVLRT-- +>tr|I4D6N2|I4D6N2_DESAJ Transcriptional antiterminator OS=Desulfosporosinus acidiphilus (strain DSM 22704 / JCM 16185 / SJ4) GN=Desaci_2512 PE=4 SV=1 +--------------STQVNCIIKGLLNELVEKKllNRQqaLSLRQTLLDREKLGAIIIpKKNFAIYHCASS---EITEPMIAVARLDKPANLINLLGKneKVTTAFLMLAPlyVKESLEIIGDISSSIIESSDFVTEINRSSNVeDCRALLEE-- +>tr|A0A0B5AMH0|A0A0B5AMH0_9BACL Uncharacterized protein OS=Jeotgalibacillus malaysiensis GN=JMA_05300 PE=4 SV=1 +--------------HKKFEKVLSKIDASLYEEELIHkkGAVTKSLTERESLGGMAIpDTGLALYHCKDQ---AVRQPVFRLYDLTSPYMLKGMDGEptEVSRLILMISPadpDHKGAEVLSSISGSLVEEEYTMHLIRNGNQQEVFQFLQK-- +>tr|A0A162MTH3|A0A162MTH3_9FIRM Transcriptional regulator MtlR OS=Thermovenabulum gondwanense GN=mtlR PE=4 SV=1 +--------------KKNIEGLMDEVIKYFN---dVVVdgNLLKEDLKRRMELSGCGVpGTGVYLLHAKSR---SVREPLFGVFGTKEKMFLKNMDGQkeGYRDFVLMLLPtegYKKTAEVFARISVLILEDKEFLTALKGQNESLFIKILLK-- +>tr|L0EGU6|L0EGU6_THECK Transcriptional antiterminator OS=Thermobacillus composti (strain DSM 18247 / JCM 13945 / KWC4) GN=Theco_2760 PE=4 SV=1 +--------------ADDKQHLVDRIIAYAGE--nfSVSdpDLLKRDLENRERLGPLLMePERLAMLHCRSE---GIDEMAICLFRLGREVNWDI-EGRpaLVRTVLTMLGPlhgPKENFELASEISMSLIEEP-FIRSLTHGSPGEAKEAMQF-- +>tr|A0A0X8GZK5|A0A0X8GZK5_9FIRM Uncharacterized protein OS=Erysipelothrix sp. LV19 GN=AOC36_04930 PE=4 SV=1 +--------------SNSIEDYIRAMCLvAMTQ--SESepELVVKSMLNGGHKNSFAIpNTHLAFFHERSA---GIKKSTLKVFPLTQPIQILGLDNRnhWVNTFILLLAPeklEQYELELLSFTSSLIIDNEEAPGIFEMGDQNEITTYLVS-- +>tr|F8F340|F8F340_TRECH PTS modulated transcriptional regulator, MtlR family OS=Treponema caldarium (strain ATCC 51460 / DSM 7334 / H1) GN=Spica_2252 P +--------------GKDWNEVLQQLIYACKGLGCINdeEAAFAALAQRSTDHGILLpDNRSLFLHARST---AVTRPCFTIHRLREPLVVDAV-QWssAPRTILLMLAPqnlNDRDLSLLNEISVSLLDTTILE-YLEQETEQ---------- +>tr|A0A061NYM8|A0A061NYM8_9BACL Mannitol operon activator, BglG family OS=Geomicrobium sp. JCM 19038 GN=JCM19038_1455 PE=4 SV=1 +---------------RDVWQGIEASVEEMHRLGFVDhvDAIVTMLKERERVGGLAIpNTDIALYHGRND---AVRDPFFNVIDLEEAISLPSMIEGheWVKRIVVYAAPkeiTPHHLSFLSYVSTLFIGSEQDVKVFSEGKREELLALLEE-- +>tr|J9HV15|J9HV15_9BACL Transcriptional antiterminator, BglG OS=Alicyclobacillus hesperidum URH17-3-68 GN=URH17368_1109 PE=4 SV=1 +--------------GGKLADVIEQAAQDAVQVGHAVdaAGVKQAILQRERLGSIVLpGKGLAVLHARSN---ALTDCHIAVYRLRQAIAVKGVGVQkeQVDTVLVLLAKideELEVIELLGRLSAALVTDDDLVDALRTFDIDGLQREMLT-- +>tr|C8WQV6|C8WQV6_ALIAD Transcriptional antiterminator, BglG OS=Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / JC +--------------AQTMDDVIQLVGLDLVRQGRASdaGPIVAAIERRERLGSVVLpGRQLAVLHARTD---GIDGPFVGVYRLERPMWTRGVGEDePVAVVLVLLARvqeDPGAIDGLGRISAALVESEALVEALKSADEEEVRRRLYD-- +>tr|A0A1B7KN40|A0A1B7KN40_GEOTM PTS sugar transporter OS=Geobacillus thermoglucosidasius GN=A7K69_13955 PE=4 SV=1 +--------------SHSIKEVLAEACHQLWQKGIIRdsGKVLAELLRRERLGGLGIpETPLVLYHARSP---AVLFPSFTIYRLTKCQTVKGMHDQpvDVNTILLLLAPdsaSQETLSVLSHISTLVIKDEDSIALFAKGDREQAHSFLSH-- +>tr|A0A1H1P8U0|A0A1H1P8U0_9BACL Mannitol operon transcriptional antiterminator OS=Paenibacillaceae bacterium GAS479 GN=SAMN05444162_0666 PE=4 SV=1 +---------------eESLETLLLVACSRQELREAVLdpSVIAMQLIQREMQGTQLIpGTDLALFHTRSE---LVTQPVLMLFELEQPLDMEENdahdtDD-gtYLKRFLLMLAPrtlNRESLEVLSEISATLLDQ-AMIDTLATGKEQVIRKRLAA-- +>tr|A0A1N7IZX3|A0A1N7IZX3_9BACI Transcriptional antiterminator, BglG family OS=Salimicrobium flavidum GN=SAMN05421687_10384 PE=4 SV=1 +--------------GRDSNEFLHHIIGELAEKDLLPydPRVVQQLLDREEVGGLGIpGTSAALFHTRTE---SAGSISFTVHFLEHPVTVNSMDGDsiDADTVLLMLTPpepPEESLETLSFISSLFVEEEESREVLESKEEARLKQYFSR-- +>tr|A0A1M5BDK7|A0A1M5BDK7_9BACL Transcriptional antiterminator, BglG family OS=Seinonella peptonophila GN=SAMN05444392_12125 PE=4 SV=1 +--------------GWSNEEVIRQIGHDLISEGflRD-gqSWFEQTLL---------QlENGLSVYQFKGD---EIEQPFFAVYELQESIHK------GVDQLIILLTPkdaKKEVQELMLTL-ESLCQQSGAIEKLATNDPEIIRTYFLQ-- +>tr|A0A1H6GMQ3|A0A1H6GMQ3_SELRU Transcriptional antiterminator, BglG family OS=Selenomonas ruminantium GN=SAMN05216583_10613 PE=4 SV=1 +--------------AMTVQEAAAAIGKRVAE--DHAqaKEIEKALLAREDQGSTAIlGSHMIMLHCRSK---AVESLRLGIVHLGEYFLYPAEP--geKIRTAIVLLAPescSCYELETIGHLSSILLERWGLLEVLHEGDERHIHGELIR-- +>tr|A0A1Q3RQR7|A0A1Q3RQR7_9FIRM Uncharacterized protein OS=Clostridiales bacterium 38-18 GN=BGO41_03070 PE=4 SV=1 +--------------AKNSEQLLKQIADANAT--DSKhkKQIISVLQEREKLGSTVLqGEGIALIHGKSE---VIKEMTFSVWRLVKPITMQAF-RRneLVDKAVVMLIPenaSKVQLEVMSLLSKALVEDNLMIQMISDADEKLLLDHIKG-- +>tr|A0A1U9K8S4|A0A1U9K8S4_9BACL Transcriptional antiterminator OS=Novibacillus thermophilus GN=B0W44_12370 PE=4 SV=1 +--------------NVSLEDGLNDICRDFERSGLLSgaNSVVEGLLAREQAGGVAIpETSLALFHVRTE---EIEKPCVSMCELKVPALRKGMDGMrvPVKRALVLLAPlsmSEQRLSLMSSISALLIKSEAHTTVFEKGSETEIRALLAE-- +>tr|A0A212KA00|A0A212KA00_9FIRM Uncharacterized protein OS=uncultured Clostridiales bacterium GN=KL86CLO1_12464 PE=4 SV=1 +--------------LKSTEELIEFTAETVGR--SDLqrAAIARSLFARERYGSTLTpDGRCMLLHCRTP---GVSQAYLGVVWLDGCITVAD----gqRPRSALIMLAPqdgPRQAVDVLSAVGSSTVEYPWLVDALCTGDRDQCYAAVEQ-- +>tr|Q3Y3R3|Q3Y3R3_ENTFC PTS family porter component IIA OS=Enterococcus faecium DO GN=HMPREF0351_13057 PE=4 SV=1 +--IFDASMLKYHQAAQTWQNAIRISGQELLAKHSIEEQYVNNIISNIENFGPYmiIAPGVLLAHAGEQ--DGVLNNGFSMHVFHEPITFPGENVFPVSVIMTIAVKDRTSYHVVERIVQWVLDEETIFSLADEKNRQRIEQMIR--- +>tr|A0A1Q8E771|A0A1Q8E771_9STRE Uncharacterized protein OS=Streptococcus cuniculi GN=BU202_06155 PE=4 SV=1 +--VFDPTMLVYHQNheGLAWREAVQLSSECLLEHGSIEERYTQKIIRNIEQFGMYmvIAPGVMLVHAGAE--DGVRQNGLSMHVFEEPVIFPSTDGMPIQVIVVVAMDKQNSYPVIEGLIHWITQEESLFTLRDSGNRLKCIQKIN--- +>tr|S2LDZ6|S2LDZ6_LACPA Nitrogen regulatory protein (Enzyme IIA-NTR) OS=Lactobacillus paracasei subsp. tolerans Lpl7 GN=Lpl7_2300 PE=4 SV=1 +--------------IVNKTTILRTISDALSKvSGQSAPQIQSAFMEREGVGNTALESGIAIPHAVLD---GRQVPVLGVLSYPSGVkDWKDLNGQPVTQVLAILMGKdeitEQEANDIKRFFVKLASSDFLRKIARSKDSQTVVAVIKQ-- +>tr|A0A135YLK1|A0A135YLK1_9LACO PRD domain protein (Fragment) OS=Lactobacillus crispatus GN=HMPREF3209_02578 PE=4 SV=1 +-----ENNFYIDNKHKNYKAVIAELSTKMSKSGIVGKDFENKLLEREKISSTAFG-LVAIPHAIDY---DSKFSQWFIYINPKGVDWLGQ---KIYLVFVLAYSskdDDEFRKVFDDLSTIVIDDKRVADLINSKNYNDFVNRITK-- +>tr|A0A1L8ZNA7|A0A1L8ZNA7_9BACI Uncharacterized protein OS=Bacillus sp. VT-16-70 GN=BLX88_08575 PE=4 SV=1 +--LLRPNLFFRNVEIESDIELITFLAQSIIQQGYAPDEFLPLTIKREKISSTAFGGMIALPHPFNP---CGYENVIAIALLKKPILWGETK-EKVQAVFLLSLKKdNEqEIqDLYDRLLLIMDQPSLQTQINKQESFTDFVAFW---- +>tr|A0A242DEP6|A0A242DEP6_9ENTE Uncharacterized protein OS=Enterococcus sp. 3H8_DIV0648 GN=A5875_002372 PE=4 SV=1 +-----ENYIVKIKRVTDWAEAINCAAVPMIESGGILPDYPAKIIANYHEMiPhIVFGKEIAVPHANFE--SAVNQLGMCLLVVEEGVRFTEH--QYVHLILLLATPDkNSHLSAMLQLLDLSANDLDVQQIITAETKEEIHSILRKY- +>tr|Q8EVW2|Q8EVW2_MYCPE Transcriptional antiterminator BglG family OS=Mycoplasma penetrans (strain HF-2) GN=MYPE4470 PE=4 SV=1 +----KRDFINiFDEKNLSWEKAIKLCTDSLIKSKRINVNYIKAIINNINKYNSVitLSNKIAMPHASY--LDGVNKLSFTFNIFKHPVVFPGKSKFNISLIIILAPEDnEKHIKPLFELVDILKQEENVNRLLKMKDTNEIYQFILEG- +>tr|A0A1C5Y755|A0A1C5Y755_9CLOT Probable licABCH operon regulator OS=uncultured Clostridium sp. GN=licR_5 PE=4 SV=1 +------KFCQAGVEAETWEEGVWIAAEPLIREQYIRESYICEIIRvnREYNNFYLMGEELSMPHAAPS--AGVLRLAFSMATLKKPVKVPARNGKtaEVRVILILAAVDtKQHAGALEEVADIFDRQDAVERLLNSQSSENLYKVFQE-- +>tr|B9Y9G7|B9Y9G7_9FIRM Putative licABCH operon regulator (Fragment) OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_02473 PE=4 SV=1 +------------GRLNDKNQLLKKLCELAAQKyNFDLSELLASVLEREKLGFTSYGNYVAVPHTMTRI---SDETFITAGLLHTPLKWDED--NVVYLVILISLGKkENHdlYSLYSSLSKLISNKDFIETLIKTPSIDKLLDFIQ--- +>tr|A0A1Y4SGA3|A0A1Y4SGA3_9FIRM Uncharacterized protein OS=Lachnoclostridium sp. An131 GN=B5E77_00740 PE=4 SV=1 +-------------ENMDWRDAIFQAAFPLLSGRYIDRSYIDAMIMNVEMFGmyTWFGNGVYLAHAKAE--NNVYRSGVALMTIRKGIMFREQ--KKVFLLIVFASIdQKEHLSVLKEVVKLCNNVDKIQALLECQDEEALYQTI---- +>tr|G1WK34|G1WK34_9ACTN Uncharacterized protein OS=Collinsella tanakaei YIT 12063 GN=HMPREF9452_01697 PE=4 SV=1 +-----QEFFSIEPDVANWREAIDLMGGRLVDEGYAFDDFCERLLEREEMSSSAYC-DIALPHPVD---MDARRTAVSVALFPRGLSWQGR---TVHAVLMLAIKRDDrafFSELFNHIAVVLTIPGAMRSISRATTYQQFLDAML--- +>tr|A0A243VZS8|A0A243VZS8_9ACTO Uncharacterized protein OS=Actinomyces sp. CtC 72 GN=BW737_12455 PE=4 SV=1 +----TDERLFVHTkSQLDRDDALRTCHSLLAREAAVDDQHLEDVFDRERRASTAFGGRFAMPHSLYM---DAARTALAVLTSTRPIPWGGH---EVNLVIMMAVSPrDraVFRDVLDELVRILSDPAGVDALIGAGTsYSRLMETL---- +>tr|C5EEI0|C5EEI0_9FIRM PRD domain protein OS=Clostridiales bacterium 1_7_47FAA GN=CBFG_00739 PE=4 SV=1 +-----QELFFPDIKAADKPDALRQIIERVGKAVKLKESFYESVMEREKIVATELPNGFAFPHPLGT--DMAECSFFSISVLSNPIRWKHR---KIQIVLLTYVKGkvTSDLEQfYESFATLVSNKEYAVSLIENPTYEKLVEV----- +>tr|U1LYE9|U1LYE9_9BACL Uncharacterized protein OS=Exiguobacterium pavilionensis RW-2 GN=M467_10625 PE=4 SV=1 +----------------------------LMEQVNIDPTYAETVYARERTGPTSIGQSVAIPHGNPE---HATTNRIDVLVSNEPIEWGQE---KIQLVFLLQFRDSDatfSSHLFEEIAALTENPTLVRKLIGTKDDTAFRKLL---- +>tr|F0Z0M0|F0Z0M0_9CLOT Putative phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Clostridium sp. D5 GN=HMPREF0240_02651 PE=4 SV=1 +---LNEGVVQVKFQAESWQEAVREGVSLLEKTGAVEASYADNIVSNILQmGPYmAIMPQVFFSHAENN--GNVYSAAISILTLEKGVTVGRDDCDPIRLVITLAAPDsTAHLRAVAQLFSILRKRDNVDKIINSKNCASIVKIIMQQ- +>tr|A0A1K8HIZ4|A0A1K8HIZ4_STAAU Putative transcriptional antiterminator, BglG family / PTS system, mannitol/fructose-specific IIA component OS=Staphylococcus aureus GN=ulaC PE=4 SV=1 +-DLLPEHRIIINKQPLSIESAITVAVQPLINDGIVNSNYTAAILKQLEQFGSYmvISPHIALIHAGTDYV--QNGVGFALTYFTEGIFFGSKANDSVHLVITLATDhPNAHLKALGQLSECLSNDLYRQDFLD--------------- +>tr|R5EHY1|R5EHY1_9GAMM Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Succinatimonas sp. CAG:777 GN=BN779_00897 PE=4 SV=1 +---LPKTQILSPLFCFSKKRLFEEIAEC---AAFITkktsKEIIVALNEREKLGTTVFFQGVAIPHAVIQ---SSTPTFAVLSILDKPITFNSIDAdeQLVDIAFSLFISpkDdVEKVeSLLKSLTIVLSNVDLLNAMRLSKNEKHkVETIL---- +>tr|S6CIV2|S6CIV2_LACCA Transcriptional antiterminator OS=Lactobacillus casei subsp. casei ATCC 393 GN=LBCZ_0237 PE=4 SV=1 +-----------HINESSSEEAIEYLLRKSEY-----LNLLPYFQKRESMSPTDIGHLVAMPHPFLKG--AETTAKVIVGINRQEIPWGHQ---KVRLVVIYIPAadLKTNKNFFNDVYEHTSDLAEVHALLETKTKQEFIDVWNR-- +>tr|C1A8X6|C1A8X6_GEMAT Uncharacterized protein OS=Gemmatimonas aurantiaca (strain T-27 / DSM 14586 / JCM 11422 / NBRC 100505) GN=GAU_1644 PE=4 SV=1 +-DLLSAARLRVPMSAATLADAAHELARCLEEGGSLShPELLQERIEEARpEDVVGLADRAFVVHYRTE---AVKDLVVALGRAVKPVCRVLDdeEKQCARIVILVCSPPrqlARHLQVVGAFARALSKPAHVDALLAADTPGAVMGLP---- +>tr|A0A0S8HC16|A0A0S8HC16_9BACT Uncharacterized protein OS=Gemmatimonas sp. SM23_52 GN=AMS25_05530 PE=4 SV=1 +-RLLPPDRIVVGLKATTCEGAVAQLLDRLAAAGLISdRGAVDELVAADVsaGELLNLGPRTLLAHYRTD---AARELAVAIATSATPFAFAPAKADEAVVFVLIVAPRsaaKYHLKTLAALSRLLGTPEVVDALAKATSAEEVVELI---- +>tr|W0RIA0|W0RIA0_9BACT CBS domain containing protein OS=Gemmatirosa kalamazoonesis GN=J421_3277 PE=4 SV=1 +-DLIVAERIVVPLQADDLPGAARELLARLVASGAVSqPERLRERVEEERpEDLVGMGNKAFLLHYRSD---AVRELVVALGTAPSPIERELGeseETQSARIILLVAAPPrqaSLYLATVGAFARLLSKPQVVDAVLAQPTADGLAALP---- +>tr|A0A202DI68|A0A202DI68_9BACT Uncharacterized protein OS=bacterium F11 GN=BVX98_07205 PE=4 SV=1 +---LTAGTILFLEPSEKKSMVLKPLVQRICENDPsVPlQRAFQSVMEREKVTSTFTQTGIALPHARLPK---LTRIHAALGVLPHGFQSPKEGAPLTNFIFLFLSPEgelSRHLQVLSKASWLFQNNTLKESLFQTNDPTKALSLIQA-- +>tr|A0A1V8YY66|A0A1V8YY66_ENTGA PRD domain protein OS=Enterococcus gallinarum GN=BH745_13345 PE=4 SV=1 +----KEPLFICDQDFETKEEVLHFLCHCINEQYQMPNNFEALVFEREAFFGTDFLPMVAFPHPNVLI---GSETVIAVAHLKKPIFWYKQ---SVRLVFLLVIAEQDHLKAksLnDHLIKICTSSEKVNELIATNDFITFIHHLK--- +>tr|G5IMN2|G5IMN2_9CLOT Uncharacterized protein OS=Hungatella hathewayi WAL-18680 GN=HMPREF9473_04760 PE=4 SV=1 +---FQKELFFNDIQAADKDEIIREMVARISRVRTISDDFLASVLEREQMQDTSFG-SVAFPHTNGI---ISNEDIISCAVLPQPVNWGNS---RVQIVILVSYREdfvKKHDTFFEFVLELIKKQGMVNKLKTEP------------- +>tr|A0A0U5K1I8|A0A0U5K1I8_9CLOT Putative licABCH operon regulator OS=Clostridium sp. C105KSO14 GN=licR_4 PE=4 SV=1 +----RPERFLPHISGNTKQEVLANIYKVIQSQEKVDDDFLELVMEREQLIQMNYGTQIAIPHPLHIA---SEHSFAYVAILPEPVSWNGS---PVQVVLLISIGrtgDSEEMrRLFyETTARFSLNKTAVEALIESPYYSTFIQLLKN-- +>tr|B9YDX3|B9YDX3_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_04047 PE=4 SV=1 +----SEKLFYRNIQIEGYENIINMMTDDAQKLGLCHSEFKKEVFDREQLSSTAYDSSIAIPHSLY---SNCKNSFMAIMINDEQVYWDDH---KVNIVLLIGVKTgdENFfKTIVDNIIPFFSENSNILKCLSINTYDDFVEKLSN-- +>tr|W1XN09|W1XN09_9ZZZZ Nitrogen regulatory protein (Fragment) OS=human gut metagenome GN=Q604_UNBC13982G0001 PE=4 SV=1 +------------------------------------QRLVGAAVGVDKHRAVGLDHDEALGSGKVG----VQAT-------GVVHGAGGNDNQPVDLLFALLVPAdqtKTHLHTLSLVAKRLADKTICRRLRAAQS------------ +>tr|A0A1D7QZQ5|A0A1D7QZQ5_9BACI Putative licABCH operon regulator OS=Bacillus beveridgei GN=licR PE=4 SV=1 +--LLPENRITITDEELNCEESVFQSVELLEHKLCVLPDYKHAVINRLKSNGPYmlVTHHVALLHAKPE--EGALEPSMSLLLCKKGVNFNKPGFDPVYLIFSFAATDdYSHLQALSELLLVVGEQRHVNALREMQDTREIRPYLQ--- +>tr|A0A139TLX1|A0A139TLX1_9BACT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Akkermansia sp. KLE1798 GN=HMPREF3039_03180 PE=4 SV=1 +------------QPDTTQEQALETLVDSMAEVldERQSRHIKNAVLLREETQTTYLDHGLAVPHGRTTA---LDSMYVSVGISPEGIRWPDGA-QTAHLIVMLGVPTvmvTGYLTTMQKLLRWHKNAPLGP------------------- +>tr|A0A1C7PCG1|A0A1C7PCG1_9BACT Phosphotransferase/anion transporter OS=Akkermansia glycaniphila GN=AC781_05895 PE=4 SV=1 +------------GPVQTRAEALNVLSEGATEGlsPVLSAKVLAHAEVREESVPTYLENGLAVPHARVAG---LPGISLMAAYLPDGVPWPDEA-SMADLVIFIAVPMsqvSDYLFIIRKIIRWHKSVPCAE------------------- +>tr|A0A1W1IGC6|A0A1W1IGC6_9LACT Phosphotransferase/anion transporter OS=Trichococcus pasteurii GN=TPAS_1629 PE=4 SV=1 +-------------EVHGKSELFDYVSGYLLKAGKIDsaEVLQEELRWRESMGNTLIEEDFAVPHIESS---NVNETSMILTRLKYPvLNWKDDY--SANTILFMLIKKEeepEILQDVKRIIKSLAYEETIELLKQA-EKRKIDIVL---- +>tr|A0A0E3ZBC1|A0A0E3ZBC1_9FUSO Uncharacterized protein OS=Sneathia amnii GN=VC03_02310 PE=4 SV=1 +--ILKEENIIFNYDAKDIYDALEKGCSLLEG-EFTDKSYTKDILSIYEKNNSHiiRYNGLILPHTKNN--NNVHKTGVSIISLKEPVNIKETG-EMIDTVVSFSIKDeKKSLDIISNLINMVFKSEFK-EILNEKNKYKIVEYLKN-- +>tr|A0A0P8GBG1|A0A0P8GBG1_ECOLX Transcriptional regulator (Fragment) OS=Escherichia coli GN=AN669_27725 PE=4 SV=1 +-----------I--------FERRSFFQLLQKHDNDDRLLALLLLNTFTPRAQLASALNLPXTWVAER---LPrLKQRY--------------------ERTcCLA-sRP-------------------------GLGHF-------- +>tr|A0A0L0GZT3|A0A0L0GZT3_9ENTR Frv operon regulatory protein OS=Trabulsiella odontotermitis GN=GM31_15860 PE=4 SV=1 +-----------NARDEAWQSVMANICKRLTNDGHLTVDEAWRIEQREREGENLIVNQLAIPHCWSERQ---THFRGYFITLAQSVSVNNE---PVSHVLIAcASASaRQELKIFSYLASVLYRYPP-TTISGLSGYEDFLALLRG-- +>tr|R2T7G5|R2T7G5_9ENTE Uncharacterized protein OS=Enterococcus pallens ATCC BAA-351 GN=UAU_00858 PE=4 SV=1 +-----------VQKNESWFEILERICSRLEESLVISREEATKIIEREKSGNPLLINNYSVPHCISKRE---NFVICIYIHLDKPVMVETT---MVSHVLLTmMNPNvNKSINIFKFLYRYLQEHEE--QLATIETYDEFIRFVEK-- +>tr|A0A1G3MTI1|A0A1G3MTI1_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWC2_52_13 GN=A2Y31_12505 PE=4 SV=1 +---VSEDSIFLDRDFKTVREVHEFLSDEFSKDlGMERDTILGLLEEREQLSSTWIGHNTLLPHNHSP---EIKGISMIFIRCGAPLVLGDG--NRVKYIFSILTSGsnqDLYLGILQGIGKVIGKRS--GELDNCQTPAEVLDILSDS- +>tr|A0A1V6JK76|A0A1V6JK76_9BACT Putative amino acid permease YhdG OS=Bacteroidetes bacterium ADurb.Bin008 GN=yhdG PE=4 SV=1 +-------------DSsIGLKKLVGSIAHDICHDfgTVDAKVLTKKLLKSSIVDPILIAPHVTILHGNLE---SLVRPALHVITSLTGIEKTAGkeeaNgNDYIRVLFILVCPGknpKLKFRLLSRLMDIVDRYNFIEKICSLTNEREIKEYLLH-- +>tr|A0A1Z9BMG2|A0A1Z9BMG2_9BACT Amino acid transporter OS=Rhodothermaceae bacterium TMED105 GN=CBC65_04160 PE=4 SV=1 +-------------QFkKDYESLLTQVANHMTSRiNCDANLLRAR-FAEGPDDHAMtLAEGVCLHHVRIP---NATSSEMVLV----RLAKPTVfkeLgDESLHAIIFLASSThnaTQHLRILAHLAEVIDNGSFLAHWDKAKDETDLREILLR-- +>tr|A0A1N6XSC7|A0A1N6XSC7_9BACI Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Domibacillus enclensis GN=SAMN05443094_10541 PE=4 SV=1 +--------------SESKESALNKMSVSLSANDIIEDsaFFYKEIMEREQLGNTHIGSGAALVHSIA---QTVKQEGIYLYYLSNPLtHWHFNETHPIKLIVLYAIQSvdSVNLKCFRKFSSLCADDELLQELIDQQySVEAIKKY----- +>tr|H3NPQ9|H3NPQ9_9FIRM Uncharacterized protein OS=Helcococcus kunzii ATCC 51366 GN=HMPREF9709_01331 PE=4 SV=1 +------NSIYLkHLKVKTKNEILKSLSLEASKYiNLEKEYIYTQFQNRERLGNTSFSNGVAIPHILEP----VNtDTFMIISSLDKPIIWDDN---KVKIIISLFIGKdNGDMTLfYDKLGTYLNNIEAINNSANFQEIEEFLELFLN-- +>tr|A0A1D4VHX8|A0A1D4VHX8_STAAU PTS system mannitol (Cryptic)-specific transporter subunit IIA OS=Staphylococcus aureus GN=ulaC PE=4 SV=1 +-------------HVENIDEAIAKASDVLVANHFIDIKYIHEMQQVFDDSYMVIMQNIAIPHAYSE--KHVHKTAMSMMILQEPIYMSDG--TAIHIIVPIAAVDkVTHLRALLQLRDVAQDNDAIKRIIQSRKNSDVNEILKN-- +>tr|E5VW69|E5VW69_9FIRM HTH domain-containing protein OS=Anaerostipes sp. 3_2_56FAA GN=HMPREF1011_02244 PE=4 SV=1 +-------------DTQDWKYIIELLFSDFSENRYVSENYLADVLQRESILSFSLQPSVTIAYSMKA----SSKTVLSIATLEHRIKINSH---KTRIVILAAFRLE-ERTMLFRLINeLLYSGANLNDSRFLKTKEEFLDFFER-- +>tr|A0A1Q9JIE6|A0A1Q9JIE6_9FIRM Uncharacterized protein OS=Eubacterium sp. 68-3-10 GN=BHK98_07595 PE=4 SV=1 +-------------GHGDPYSIFRDMAADFINAGFVTSDFLNDIIRHEENSTYAICPGVAYIYSLIP----AEKSAMSILTLDHRITWNTH---KIRVFIMTCFTLE-DMPITFRLANlFYDEAYDLPKIKMEENPDVLTRYYLS-- +>tr|A0A0R2BZW3|A0A0R2BZW3_9LACO Uncharacterized protein OS=Lactobacillus coleohominis DSM 14060 GN=FC35_GL001297 PE=4 SV=1 +-------LILWNKKmPTDKESFLKAISDYLANEQLIAnsQKLLIDLKKRESVGNTIVYPGLAIPHTQS---SSVQETIMLIASLKEKVSWSEGE-TVSKVIFMLLPvhPQKSDLLELKKLFVQVADDEFMVKVLTG-SRKDIQQL----- +>tr|A0A0E9FFJ9|A0A0E9FFJ9_CHLTH PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC OS=Chlamydia trachomatis GN=ERS095036_14029 PE=4 SV=1 +-------------------------------------TWLXSLLKREELESTEIGKKFALVHGNQ---KYIKNSSLSFIKLREPIKWKVD---TVQYIFVIAAKAEDYskysMKEFFKIINIVLNNGD---LEAIDNYEDLLNLFF--- +>tr|S0L4R9|S0L4R9_ENTAV Uncharacterized protein OS=Enterococcus avium ATCC 14025 GN=OMU_00045 PE=4 SV=1 +---LSAHQVHFKKTVDSFDTILDILASGMLIEGSISPNYITALKKEGFHEHLIIKDGIALPHIKDD--QHIYATSISLLKLEQPILLANEE---ISIFILLAADeKKEHLRAFEELFCILENEKLYDALLQISDYDSLNKVLKE-- +>tr|G1VUB2|G1VUB2_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium 2_2_44A GN=HMPREF9022_03593 PE=4 SV=1 +------------NTCESVSDFFLQSCQTLQDLHYVSDTFYDQLMERERLLSTSFETGIALPHTTE---NNARKSGILFAKFHTPMQWHKN---KIKCAFLIVTAkEDIHlLNIIyKVIVDISSSNQHVNRLYKCQTSEDVKRLIF--- +>tr|A0A0R1HNU5|A0A0R1HNU5_9LACO Uncharacterized protein OS=Lactobacillus kimchicus JCM 15530 GN=FC96_GL001420 PE=4 SV=1 +-------------EITDIETFMQVVEEIALRKKLIQagNNLRVDIKAREAMGNTRVGVDTVMPHVKA---EYVIKPTVLIIRVRQPLTWQDQ--LPARVFIILLVRePDPFL---EDFIIRLVNEDFIDELADFNQPPES-------- +>tr|A0A1X7QHY6|A0A1X7QHY6_LACCU Putative PTS system, galactitol specific IIAB component OS=Lactobacillus curvatus GN=LCUFL03_220002 PE=4 SV=1 +-------------RVT-KKDIFQIIRNSATQTKTIDlsDTIIQDLILREKDSSTRIAKHTVMPHVIA---DYVQKNMILIIRLDHPVQWLDK--GEVQTIIVLLIRqNDSYL---ETFLEMCCDELFLKELSQAQYSVAD-------- +>tr|I5BSZ2|I5BSZ2_9RHIZ PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN OS=Nitratireductor aquibiodomus RA22 GN=A33O_18659 PE=4 SV=1 +-------------TSITRKAALWALAAQVAtfRPGLSKIDIASALYARERLGTTAIGGGVALPHTVL---SGLEESMIVVRRLERPVEFEAADGLAVDTLVALMGGrHDiKWLrTALLRLNRLGKDTSLAQRLREATTRSEAVAAIK--- +>tr|B0M9X7|B0M9X7_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Anaerostipes caccae DSM 14662 GN=ANACAC_00350 PE=4 SV=1 +------DLLFFEEaAGKGWRQIIKKMGKHLECRGCISEQYTEDAIASVDEWGPYmvFIPGIAFVHAGPE---HVRIPGAALTVLDQEIPFGEEGNTYVKCIVMFAVED-EGNRLLTDLVSILERGDNVRKLLEAEAADDL-------- +>tr|D4H3L5|D4H3L5_DENA2 Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Denitrovibrio acetiphilus (strain DSM 12809 / N2460) GN=Dacet_2355 PE +---ICDSTIMYRLCGANRDEILNQILTILGRFTTEeKINIKKNLLFKESIISSSLS-GVAVMVADYDQQVNHSKTVFAVAYLDTPLDFKAIDGKKTDIAILIIPANKTEQLILtTRLNGLLNSDEFVKTLRSAPTRSTLIQRIRE-- +>tr|A0A1F9MDX6|A0A1F9MDX6_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFOXYD12_FULL_50_9 GN=A2511_09815 PE=4 SV=1 +---LANGAVLYRIHGNNRDEIIDELLAALPYSSTFdANTVKVSILARESLVSSSLD-GIAYMTTAGSLPVFFEKTMVLMAFLEKPVDFKALDSRSAEAIFLVLPANTIEQEILdRKLRRLSMSPRFLTGIHQQMTRKLLLDFIAQ-- +>tr|A0A0R1JGV2|A0A0R1JGV2_9LACO Uncharacterized protein OS=Lactobacillus nasuensis JCM 17158 GN=FD02_GL000582 PE=4 SV=1 +-------------AGQTVQAAMTDLGRYFQEHAIIAepAAFARAVAKREALGSTYIGAGIATPHYVAP----GLTPTLVIARSQSPLAWPDG--HTVHLCLVLVLPPGGADAQMIKLMTALADATWLQRLSTATLP----------- +>tr|A0A0A2W0E1|A0A0A2W0E1_BEABA Stationary phase-inducible protein CsiE OS=Beauveria bassiana D1-5 GN=BBAD15_g904 PE=4 SV=1 +---------NFTSRHLSWQQSIRKAAQPLREKGIIDAQYVRNMVKQIEdHGiTTYLTPDILLLHDAPP--AGATEGALSLLKLKYPLHFELSELSlTPRLIVIFVPTsNLSHIQLLEEFNALISDDKRLEQLLNADSLSQVKCCIH--- +>tr|A0A1B9KG08|A0A1B9KG08_9GAMM Uncharacterized protein OS=Gilliamella apicola GN=A9G13_00590 PE=4 SV=1 +---------GISRSQLNWHKAIDLVGQPLIKRGLIKTNYLQEIKENINkFGmYMYLTPNIVLLHASPI--DNQHLPYLSLLKVTKPIPFKIGQKSaAASIIFLLVPEkTASHIKLLEQLNVLLTNEQKLNDLLKANNIDSIERVLF--- +>tr|A0A142WR71|A0A142WR71_9PLAN Inner membrane protein YbaL OS=Planctomyces sp. SH-PL14 GN=ybaL_1 PE=3 SV=1 +---LLPDHAVFDLQAATSEDAIAILARRIPPTLLPEgQDIAALAVARERELSTDVGLGVAIPHARCP---GLSRPLLIFGRAASpGIRFSVQSSEPVTLLFLLVTPLekpELQVVLLGKLAGLAGNPEIRRQLGEAFTGEEVHQLLQE-- +>tr|G5HDN2|G5HDN2_9FIRM Uncharacterized protein OS=[Clostridium] citroniae WAL-17108 GN=HMPREF9469_00694 PE=4 SV=1 +---FKPEYVQKVTRCDNWEQALKLAAEPLIQDHRLSREYVDATIENCKINGPYfiLREGFCIAHALPD--KGLIKPCLGLLFIQEGVDFGHEFFGPVHMLFYTCFREsgQWNLKILRSLISLAEDNVKCGEIA-AQDCQRMYEG----- +>tr|A0A1B3CFQ0|A0A1B3CFQ0_9PSED PTS fructose transporter subunit IIBC OS=Pseudomonas corrugata GN=AXG94_19535 PE=4 SV=1 +------------------------------------------------------------------------------------ATLEA-----AEWVLLVAS-GpvdLSRFvgkrlfrstpaLALQDVDSVLRRGAEEAA---------VLVES-D-- +>tr|R4I1J0|R4I1J0_9GAMM Fused fructose-specific PTS enzymes OS=Serratia symbiotica str. 'Cinara cedri' GN=fruA PE=4 SV=1 +-------------------------------------------------------------------------------------SLAD-----AELVIIVGK-TtlaNAILndklvyigelkHAIRKPQAFLKQAKILAK---------IYQAP-N-- +>tr|A0A1B9NRN3|A0A1B9NRN3_9GAMM PTS fructose transporter subunit EIIBC OS=Gilliamella apicola GN=A9G44_12205 PE=4 SV=1 +-------------------------------------------------------------------------------------NATS-----ADVIVAVGS-GtisDKAVvgkkvyavddlnQIFANPKQILTDAQSKAS---------VYQQT-A-- +>tr|A0A1Q9GJ63|A0A1Q9GJ63_9GAMM PTS fructose transporter subunit IIBC OS=Photobacterium sp. 13-12 GN=BIT28_13865 PE=4 SV=1 +------------------------------------------------------------------------------------AQISE-----AECIVIAAN-TavdTTRFkgkkvyqsgvdACLADPKAYLEQAIAQAS---------VLKNV-Q-- +>tr|A0A1Q9YDF7|A0A1Q9YDF7_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium NYU-BL-F16 GN=BM735_06990 PE=4 SV=1 +-----DECFEIEPEGKSPQEILKAMSLRLAKLNLAPGKLMESVLERESLCSTAYE-GFAIPHPLHP---CAFRPSISVALFPDGFNWNGT---IIYCVFLMSLRNDDlslFREVYEPLINLLVHPGLPEILSKSKNLESFKKT----- +>tr|A0A1Q7KS53|A0A1Q7KS53_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium 13_1_40CM_3_71_4 GN=AUJ03_00040 PE=4 SV=1 +--RLRPELVHVAPPWRTFGATVTGLVDSLVSAGTLdaevRDDAVRAVMTREDESSTAlLDIGVGVPHARLA---GLRQAVVALAVSRAGLYEPVP-TVPVATVAlVLSPPSatADHLRILTDIATLLRSPELRAALLAAPDADAALAAL---- +>tr|E6D927|E6D927_CUTAC Uncharacterized protein OS=Propionibacterium acnes HL110PA4 GN=HMPREF9578_02005 PE=4 SV=1 +MSMLSPDRFMAMPAGTDYWSATEALVAYLVDQGLVDETFLTTLRARENEATMLLDGLVGFPHATIP---GAERIVLAMATIPRR-----PEQPGARVVFLMGVPDKtDyddtiLITVYDEIIRLTNDPDLLNRLSQLTSYEDVFWLMAS-- +>tr|A0A143Z020|A0A143Z020_9LACT Phosphoenolpyruvate-dependent sugar phosphotransferase system eiia 2 OS=Trichococcus palustris GN=Tpal_2789 PE=4 SV=1 +--------------QMGYFDYVEEIMIYLSKRYKLSDDILDRFIEKEERHTMIYENKVAFPHLTDP---NVDKLIFVLGKIKADK-----RYDGFSLMLFLITPEkitEQqekiLMQVYDFVFKVINDTVLIDKLQQISDVQGFIEMLEKR- +>tr|H3NFI2|H3NFI2_9LACT Uncharacterized protein OS=Dolosigranulum pigrum ATCC 51524 GN=HMPREF9703_01313 PE=4 SV=1 +--------------EFTYEEKVLVALREIEDDPTLINKLFNIFKEKESENSMVYENNIYFPHITNP---SGDNIKIVVS------------NEVDQLFVFLSIPAkmtDSqeylLTKIYDKIFNLIATQELKSI--DTTSFEKFMNYGDDR- +>tr|A0A1T4P9S1|A0A1T4P9S1_9FIRM Lichenan operon transcriptional antiterminator OS=Garciella nitratireducens DSM 15102 GN=SAMN02745973_01991 PE=4 SV=1 +--------------KDDYVTAVSHMIHELVKKGQLDGSFYQRWKDREQIQEMIFDKGIAIPHAVNK---NHEKFVLSVGIYDKEIK---QNNKRVKVIFLMGIPEkidKEnqkiLTFTYDKIFSIGINEVLYQEMLEVQGVEEIKKFLLRK- +>tr|A0A1E5DZG0|A0A1E5DZG0_9VIBR Uncharacterized protein OS=Vibrio rumoiensis 1S-45 GN=A1QC_12240 PE=4 SV=1 +------------------------------------EIIETQLKQRESMSSTGMKNGIAFPHIVS---EGVTDPQLFCVTTTTPIQWGSNFG-PVTHIMCLILPKpfqKEAFLGVKNLASKLVNEDFQQFITQQNTGAELQVI----- +>tr|A0A1V3HDD2|A0A1V3HDD2_9GAMM Uncharacterized protein OS=Salinivibrio sp. MA351 GN=BZG78_02320 PE=4 SV=1 +--------------ATQCESLFREIVERVAEKDT-SMQAHAAFMAREAHSSTYLGDQVALPHIID---SSVPHPAIIVTRCQPAMTWLNQE--SVSLCIAIAIPCdieRTTLRAISRLSRRLSSSAFRRWLTHCDDIPT--------- +>tr|X1FNZ1|X1FNZ1_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=S03H2_03767 PE=4 SV=1 +---LKKENIEISLMGKTREELCMELLTLLEKGNKIQdKNFiLKSIITRDKVIDSYMGKGVIFVRLPL---ETQKNISLAMGVNKEGLDEEVFDREKIKIFLIIITPDsenEEYINLVSEMSSLLNQGSIREDILDAKDAERVKKILLG-- +>tr|A0A0E3ZB98|A0A0E3ZB98_9FUSO Uncharacterized protein OS=Sneathia amnii GN=VC03_00295 PE=4 SV=1 +----------CKIKFNTWEDTIRYGVSKMVELGIVNDDYANKIIDTINEYGSYmiITKNIALPHAKVEN--ENYKTGVYIIYLKYPIIFPGR--KRVKLLFFVHINCDDSRELIDNILQIIDNGQDLNKIQNV-------------- +>tr|C2BFG8|C2BFG8_9FIRM Putative ATP synthase F1, delta subunit OS=Anaerococcus lactolyticus ATCC 51172 GN=HMPREF0072_1088 PE=4 SV=1 +------KNLFFDIDVASKEEFFNVSQKLILKNNsEMTDKKLDVVENYDYSVSTDIGNLVAIPHAVLE---GDFKSFVAIFRLKNQIIWNKE---NVKFVFLIVINKkeKFYIDELKYLYNYILDPSNLSFMINASNYDEFVERI---- +>tr|A0A1V4RIJ0|A0A1V4RIJ0_9BACT Uncharacterized protein OS=Gemmatimonadaceae bacterium 4484_173 GN=B1H09_03165 PE=4 SV=1 +--LLSDSEIRFPEKTSTRSSILRYISLKAVELGAIYdaAELREQLELREEVVSTALRCGAALIHPLEINRMYIEKELLLLVIPPRPLPFGESSGRLTSLFFLLLFPNsHRHVHILARLNRLLRSSAFIETVLCARSHEEVLDLVYR-- +>tr|A0A095XWB0|A0A095XWB0_9FIRM Uncharacterized protein OS=Peptostreptococcus sp. MV1 GN=HMPREF1639_02535 PE=4 SV=1 +-------------TISGGNELIGACTNLISRDKSERDRIYTALKDRCDINMPYFeDLGLYLMHCKI---KGVK-SRLGFMNVVEEFESLSGYngkriQKKIKSVV-VLILEerdLYAKDLFASISSRLVeDDEFLEAIS-CLDRSKIQYIVD--- +>tr|N1ZJ96|N1ZJ96_9CLOT Uncharacterized protein OS=Clostridium sp. ASF356 GN=C820_01111 PE=4 SV=1 +-------------QIADIWDIIPLAGRMFTKEKKMADAVIMALKSREMKSETYIsSLEIMLFHCKT---DVVNHCRFGYIGLRKPFC-RKDGTGWVKGAVVMLTPEygtKVCLEVISTISSALIeNEKLITYLH-SIHQEAFVITLE--- +>tr|B0A809|B0A809_9FIRM PRD domain protein OS=Intestinibacter bartlettii DSM 16795 GN=CLOBAR_00753 PE=4 SV=1 +-------------DCDDLEELINYSSFIFANNSKSALQIQKDLKRRINISTPFVdGIDIALLHCMT---EEVENIRYASIRLSNEIMIDKE--NKTKYALFMLIPKeaqTYQRELLSNISENLIeNDEFVDCIK-HGDKEDIKGKFK--- +>tr|U2NQY7|U2NQY7_9CLOT Transcription antiterminator OS=Clostridium intestinale URNW GN=CINTURNW_1729 PE=4 SV=1 +-------------RFDNIEGIILEASKIAAKSANEEEVIYKALKEREKMSSTVItGKKFVLVHSSV---P-IPTYTFGVIRLKSGLSC-KNGngdEETINMAVIMILSSnhsKEYMEVMSYISRTIIdRDKFLKQIN-EEKFDFLYAQLC--- +>tr|U2NJM4|U2NJM4_9CLOT Transcription antiterminator OS=Clostridium intestinale URNW GN=CINTURNW_3555 PE=4 SV=1 +-------------EITTKEELIEKTSILFSKDNNEKALIKAGLLYREKLGSTFIeELGISLLHCTL---DSFEGVKFGLIRPKKEVE--DF--PNLKVVVVIIVPKknnTILLKTVSEISEAIIqDENLVKDFI-VKDKEQLLNYLE--- +>tr|V9H696|V9H696_9CLOT Uncharacterized protein OS=Clostridium sp. 7_2_43FAA GN=CSBG_00131 PE=4 SV=1 +-------------DIGDLEEIIEEASKLFSKDRKEAEEIKNKILDREKVNSTYLkDLNILLLHCKC---KCLDSGRFGYLKIKGQFK-NEK--GVIKGVLISIIPEdykEITSELMSKINGAIIeNERFLNILN-EKDSKEASQEVE--- +>tr|E4RK49|E4RK49_HALHG Transcriptional antiterminator, BglG OS=Halanaerobium hydrogeniformans GN=Halsa_1170 PE=4 SV=1 +-------------KYKNLEQLLSDAAELLADNGDEKKVIQKDLSLREEKGSTVLeHNKILLLHCRS---KVVEEVKFIVIRPENKFKI-LNEdknKAEIEIVVVMAAPLkgaEQGREVLSEISRLLIeSTSFIKAIN-SGLKNEVYFEMA--- +>tr|F9VJ29|F9VJ29_ARTSS BglG family transcriptional antiterminator OS=Arthromitus sp. (strain SFB-mouse-Japan) GN=SFBM_0210 PE=4 SV=1 +-------------TYGSIQNVIRDF--VYKTLSYNRDEIFHEILRKEMISSSYVkELGIIILHTIS---KFSKDIYIGSYILSKDIPI-YN--GNLNIIFYFIIPEelntKVLRKVIGELTSNLVkDDTFIDILK-KQDILIIREYIR--- +>tr|H3KAU2|H3KAU2_9FIRM Uncharacterized protein OS=Megamonas funiformis YIT 11815 GN=HMPREF9454_02365 PE=4 SV=1 +-------------NVNSKEELCSFVSIYLLK-ENISQILEADLKSREEKGSTIIk--DLMLLHTKS---KVIQNLTVGIIQLEKSLKI---NEKEISTVLILLVPDkvdEKALETMGVLSESIIeNTNLLDILH-QGSKAEIYLELE--- +>tr|A0A1J0GDT3|A0A1J0GDT3_9CLOT Uncharacterized protein OS=Clostridium estertheticum subsp. estertheticum GN=A7L45_05265 PE=4 SV=1 +-------------EMSSVDALIIEASKAIEKDSETTEKIRMALESREKKGNTVVtGHEMILLHCRT---DIVQKLYFGAVKLSKGLEC-LNGegkIENIKLGIIMLAPEecsALQIEVIGYVSKMLIeRVDFLKYLK-DGERDYAFNELN--- +>tr|A0A1D8GKY6|A0A1D8GKY6_9CLOT Uncharacterized protein OS=Geosporobacter ferrireducens GN=Gferi_19700 PE=4 SV=1 +-------------DVKDVDSLIQEICIEFVDNTEERTRLYTDLKNREQLGSTLLkQKEIMLLHCRT---STVKELHFTVFRLQKPIYT-RGMngeTERIQAGTVMLAPYdaeKIGLEVLSEITKGLVeNDHFSSSII-EGEREEIYNDLS--- +>tr|A0A1E3KZT0|A0A1E3KZT0_9BACL Transcriptional regulator MtlR OS=Paenibacillus sp. TI45-13ar GN=PTI45_04275 PE=4 SV=1 +-------------SATSVTDLIHQIATTFTASAERADVLEQELHERERLGETVLsQDGLILLHCRS---SVVPKLFLGVMRFAHPISA---AsqSVDLYAAIVLLAPKdssKSYLEAVNEVSKSLIdRPGFVTRVV-SGSAVELTAEIS--- +>tr|A0A1C0ABM8|A0A1C0ABM8_9FIRM Uncharacterized protein OS=Orenia metallireducens GN=U472_04290 PE=4 SV=1 +-------------AIKNYDQIIKEVSKkDFIPLNTDSKAVYNALKAREEKGSTIIpEMKLTLLHART---DGIQKPFIGLVILDEAILL-SGPnnlKQEVDRIIVLLAPKeliSEEIQLISSFSASIIeNKDFHNVIR-EGNQEELIDYLR--- +>tr|A0A0K8JIB7|A0A0K8JIB7_9FIRM Uncharacterized protein OS=Propionispora sp. 2/2-37 GN=P22_3478 PE=4 SV=1 +-------------SARTKLTLIEYIAKnMA-AEESYRELILKRLLKREEYGSTVIdEGGLVLFHCKI---KDC--LKIGVIRLLSPIEA-VSGdvQSAISTAFVILMPDdadDRIVEMLSAISKGLIvNKNFLQEVC-KGTKEAVLKHLS--- +>tr|A0A1M6GC20|A0A1M6GC20_9FIRM Mannitol operon transcriptional antiterminator OS=Dethiosulfatibacter aminovorans DSM 17477 GN=SAMN02745751_01689 PE=4 SV=1 +-------------KAGSMKEIIDYSSSLIGRNPEEVDILIKAFAEREEKGTTILsKKGMLLLHCRA---DISMEVCLKILSLSNPIEL---KqgdEQLIDTIVIMVGPVvinQKILDTMSEITRSIIa-SDFSELIL-SKREEEIEFELN--- +>tr|A0A1T5IPA2|A0A1T5IPA2_9CLOT Mannitol operon transcriptional antiterminator OS=Maledivibacter halophilus GN=SAMN02194393_00599 PE=4 SV=1 +-------------DFDNHNELIKYVSTLIGESKEDIDIIERDLLAREEQGSTVLeGKRMMLLHCRT---NGVNSLKFGVVRLFEEkpIFC-KSGrgeEEILT-VLVMMYSSsknKGHLEVISEISRNLIdEPKFVDILA-KGTKKEIFISIK--- +>tr|L8EYL4|L8EYL4_STRRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Streptomyces rimosus subsp. rimosus ATCC 10970 GN=SRIM +---LPKQQIHPHAQAITANELLETLTHDLHAAGTISdpHTFTRALHTCLTHGTHGFH-GIALLTTRN---RTVNTPAAAFARISPDLAWHGADNHQIRDVFLLTAPHkpkhhSGCLQTYSTLARHTAHAGFRRMLAGACTAEELYELFC--- +>tr|A0A0M9XFG3|A0A0M9XFG3_STRRM Uncharacterized protein OS=Streptomyces rimosus subsp. rimosus GN=ADK43_15685 PE=4 SV=1 +---LPRQRIHPYARTETTDELLRTLTHGLHAEGTISdpDTFTQTLHTRLAHGPTGFH-GIALLAARS---RTITTPAAAFARIPRNLTWPSADDHTIHDVFLLAVLHrlidTGCIQTYAVLARHTAHPGFRRMLSASRTTDELYELFR--- +>tr|A0A1M7E3T1|A0A1M7E3T1_9BACI Transcriptional antiterminator, BglG family OS=Bacillus rhizosphaerae GN=SAMN05192535_3705 PE=4 SV=1 +--------CFFRLNGQTKEELLRLLVKKAG-----AEVYLPSIESREQLSATDIGNRMAVPHPLISI--DAPETKIFVGMNSRAVQWGER---TVQMVFLLLVSErdTvLYESIFREIYQLSKTARLQDM----KSYQGFRNSL---- +>tr|A0A0S4M0F5|A0A0S4M0F5_9BACT Putative PTS system sugar transporter subunit IIA OS=bacterium 2013Arg42i GN=Ark11_0450 PE=4 SV=1 +--LLPPANVLVDVEVNSVKKLFELMGVFFENRYSLsKDVVYQALFARERLGSTMLakSSGWAMPHAVIT---SISEVLCGLVLLRNSIVFDQRGWRASVFLFVLIPPSwRDRVSCVYNEWRLLSEQkDVVETVEGMDNPSALYQYLFH-- +>tr|A0A0J1FR43|A0A0J1FR43_9FIRM Transcriptional regulator MtlR OS=Desulfosporosinus acididurans GN=mtlR PE=4 SV=1 +------------LQAETYQDTIQDIVQGIHATHLIAdrARIYDLIAKREEKGNVIIpGRHIALIHFRAE---EISEPFVSAFRLKHFIEIKGIGYssENVDTFFVMLARKDesnYILELLGKISvALVENDYFAEVLRFG-DLKDIRSEL---- +>tr|E6U8C8|E6U8C8_ETHHY Transcriptional antiterminator, BglG OS=Ethanoligenens harbinense (strain DSM 18485 / JCM 12961 / CGMCC 1.5033 / YUAN-3) GN=Eth +------------VTATNMPGLIHTIASRLLEKSVVTdrEEIEHRILKREKIGSVVIpNSRLALLHTRSE---TVAEPYIGIYRLRGQMLLHNPHSndEPVDTFVVLLAKETahpLVLESLGNLSmSLVDRPALIETLRTG-LPEEVRQKI---- +>tr|A0A1W6WB45|A0A1W6WB45_9FIRM Uncharacterized protein OS=Ruminococcaceae bacterium CPB6 GN=B6259_00375 PE=4 SV=1 +------------IPKEPFEQMVDRIAAELFRQHRIAdpKEITHLILQREKTGSIVVpQTKVSLLHVRSD---LVHSPFVGVYRIaEGEICMRGVGFvwEPVNTFLVMLARSSetaSVLEKMGRMSvALIEDKTFPKMLRTG-TLGELKTKL---- +>tr|A0A1J6FDH0|A0A1J6FDH0_9STAP Uncharacterized protein OS=Staphylococcus equorum GN=A4A34_02950 PE=4 SV=1 +----------ISTNETDKVRLLSDLENQLIDEKILGkqNSLKKDIEFREEKGNLEIYPKVLLPHIKQ---QYVKKSKIIIIKNhSSLIKWGDQM---LKVVILVLVSndiSENEQKRIRIFMRDLADETYINKLIE--------------- +>tr|A0A0F4L7Z4|A0A0F4L7Z4_9LACO PRD domain protein OS=Lactobacillus kimbladii GN=JF75_19430 PE=4 SV=1 +--KFSNDHCWFLSEVNNKQQVLEKISKILSDKQLVFPNYVNVIKKRERIGSTYIGENVALVHGIYK--EKHLVPSLNIFKLKKAINWSKNE--KVDLIINFVATknsEKDFKFIFQRMGKSIDDIQFWNSLKAIP------------- +>tr|A0A1V4RK22|A0A1V4RK22_9BACT Uncharacterized protein OS=Gemmatimonadaceae bacterium 4484_173 GN=B1H09_01670 PE=4 SV=1 +-DILTKETIEVNVDLKNKKQLITEIAVIACK-------------------------HPAMKGIAPSEVEKLLSFAVGIITTRKGIDFNSIDNEKVNIFPFVIGPednPKEHLKVLSGMARLLRNPETRSTIRKAVSPQELYDFLEG-- +>tr|K8DVF8|K8DVF8_STAXY Putative regulator of sorbitol operon OS=Staphylococcus xylosus PE=4 SV=1 +VDFLTEQDVYHVNENMTYEEVIAYLSNELINENRVDYTFISKILEREKHKSTVTG-SLGFPHTSH----LYHGIWLKLAIINQPLQDYEM----VKLVVLVATPEAEvneaiLIRLYEEILAITTKSYIINQICKDTDYITLAHILNNE- +>tr|A0A143PD21|A0A143PD21_9STAP Uncharacterized protein OS=Staphylococcus condimenti GN=A4G25_08570 PE=4 SV=1 +LDFINERDFYHLSDADDYYSVIHFLASEMIDEQRVDSKFDQTIIEREKLKSTINK-AVGFPHATH----SMEGIQIKVAILDNTIKSYPD----LKIVILIATPKTIsneaiLIRIYEEVLSITKNTYLTKKITSQTDFEDFVYLLNEE- +>tr|A0A239Y7P0|A0A239Y7P0_9STAP Putative regulator of sorbitol operon OS=Staphylococcus stepanovicii GN=srlM PE=4 SV=1 +LGSMLENNFVYLTSNASYQDVIQEMVTGLPVSLDEQLIIQENLLIREDKKSTVYG-EMAFPHTSY----SGNKLMVKAGIITKHIEEEPH----LKLVILLITPNESvndamLIKLYEEILSVASNKYLLSKLNSETSYESFINILKLE- +>tr|A0A1R7MD26|A0A1R7MD26_CLODI Putative transcription antiterminator OS=Clostridioides difficile GN=licR_11 PE=4 SV=1 +-DLIGTDTIRIIDGDMKWEDAVKISSNILANCDFVSAQYAENIIDILKNVGFYavKDNEFALLHGNDS--SLVKVSSISLLICKEAVSFGDKK---VKIIFCLASRDkKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYE +>tr|A0A0R1RYR8|A0A0R1RYR8_9LACO Uncharacterized protein OS=Lactobacillus fuchuensis DSM 14340 = JCM 11249 GN=FC69_GL001288 PE=4 SV=1 +LHLFNEENFSIVTDEHDYLALLKKKGLRLESMGAATPDFSKSVIDREQKISTVYDFGVAGPHPMA---SFAKKEVIDVTIVTNEMQYQQKE---VKIIFLINIRQGHltlHQEISRMMIELIKDRELRELMYQVKDYPSFISYIT--- +>tr|D7CUJ1|D7CUJ1_TRURR Sodium/hydrogen exchanger OS=Truepera radiovictrix (strain DSM 17093 / CIP 108686 / LMG 22925 / RQ-24) GN=Trad_2672 PE=4 SV=1 +FALLHREHVLLDLQTPSYAEAIERLLYTAIPKGGVQtQRVLRMLVEDDIGFSSEVLPGVLISHARE---RGIRQPTLCLGISRQGLSHYSSS-HTIYVIVLLLSPaelpMQAHLARLSEVSQQLAHAGQISRLVSCKTPEEVLAWFAQSR +>tr|A0A098QVP3|A0A098QVP3_9SPIO Uncharacterized protein OS=Spirochaeta lutea GN=DC28_11860 PE=4 SV=1 +QLDEPPVTYLFGFPNPQIKELCSELIARM--PDIAPsSRLIQDLLRISQEEPVLLVDQVVLIHSHR---KEVHKTQIAIGTADQDIRLPLVD-QSIRVVVLLLNPldqdPSVHLQILSRIARMIHRPEYLPALLSSRSQEEFQEKLSRIR +>tr|A0A0P7ZAK7|A0A0P7ZAK7_9BACT CPA2 family monovalent cation:protein antiporter OS=Bacteroidetes bacterium HLUCCA01 GN=HLUCCA01_01730 PE=4 SV=1 +FGLLSPDAVSMSNENQDILTLIRQLIGSRLRIDGNKlESICAAVMDNSLEYIPEIVPGIAILDAHI---PDISETVVIIHISNDGIHIPKTS-GPTRITVLVLNPdhigIDLHYRRLNAVARIFRGEGIVERLTSARNEQEVLAVLQDTG +>tr|A0A0J7HQQ5|A0A0J7HQQ5_9BACT Na+/H+ antiporter OS=Chitinispirillum alkaliphilum GN=CHISP_1926 PE=4 SV=1 +KSVFRPQRMLFNMNTSSLNEMVFKLLQNEFRNDKALhNRLTSILCKIGREEPVELLQDVLLLHTYV---PYLSETITFLGVSKKPLDVPLAS-GSPHIVIVLLDPvgqdPANHLRALSDIANLIRLPSIVDILKEVKDYGQLVEKTNQIN +>tr|E3HBH2|E3HBH2_ILYPC Sodium/hydrogen exchanger OS=Ilyobacter polytropus (strain DSM 2926 / CuHBu1) GN=Ilyop_2016 PE=4 SV=1 +IRRLSKNNFLFDFSENNPEKLLKIITDKF--SDEREsREVYEDLKDVLKKYPVELTHETLLIHTYM---ESIDDYQVYIATNKNKFSVENVK-SNPKVIIVLLSPksdpMNRHLKVLSEIAKIVTDKKMLSDILGSCSYSEFLERINQR- +>tr|U7D4W1|U7D4W1_9BACT Sodium/hydrogen exchanger OS=Chitinivibrio alkaliphilus ACht1 GN=CALK_2173 PE=4 SV=1 +FEPIQEPT----------GTPLPQVLTALaenISPSKEDsMELFGLLMSCAEAYPVEISPGIVLLHAHT---CTVTTPRVFLFHQEKSETLTPID-KKVRLLIIVLNPfygdAQQHLKTLARIARIFAQKENQEAVETYADAESLISHLKISH +>tr|A1BHK1|A1BHK1_CHLPD Transporter, CPA2 family OS=Chlorobium phaeobacteroides (strain DSM 266) GN=Cpha266_1862 PE=4 SV=1 +T--EKKSMFNFS----YLGTLVDKIPKGGkrgLFTGKRNsSDTAA-------------------------------------------------------------------------------------------------------- +>tr|B3EE21|B3EE21_CHLL2 Sodium/hydrogen exchanger OS=Chlorobium limicola (strain DSM 245 / NBRC 103803 / 6330) GN=Clim_1681 PE=4 SV=1 +L--SGGIQFSMV----PLRSQVESMLKRVsfkRISLRRNrKEPQ--------------------------------------------------------------------------------------------------------- +>tr|A4SFP4|A4SFP4_CHLPM Transporter, CPA2 family OS=Chlorobium phaeovibrioides (strain DSM 265 / 1930) GN=Cvib_1291 PE=4 SV=1 +K--GLDTLE-------RFGKIFGEAYRK-gWKPLQRQtEK----------------------------------------------------------------------------------------------------------- +>tr|A0A0L8VB39|A0A0L8VB39_9BACT K(+)/H(+) antiporter OS=Sunxiuqinia dokdonensis GN=NC99_14920 PE=4 SV=1 +MEPFMEHVEHLD----DFRKMIGQFFKKK-------------------------------------------------------------------------------------------------------------------- +>tr|G9S5J6|G9S5J6_9PORP Uncharacterized protein OS=Tannerella sp. 6_1_58FAA_CT1 GN=HMPREF1033_02032 PE=4 SV=1 +M-DVQRDYTRFI----GLRLFLENLLKKKkrWGHR--NqKKDK--------------------------------------------------------------------------------------------------------- +>tr|A0A1G3P9C2|A0A1G3P9C2_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWF1_31_7 GN=A2015_00460 PE=4 SV=1 +--LHAIDYADFNIESSDIQKGIRTLLSKMYTGSIC-EALINEMVRVSNEEPVELCDGVILLHAHV---SEIKEYRIFFGVNKNGFDLPSCP-GKFHAFFMLLAPkeqsPEKHLAILAAVAKLVQAKQFLEKIESSQSLDEFKASFKDGT +>tr|A0A1G1C3E7|A0A1G1C3E7_9BACT Uncharacterized protein OS=Lentisphaerae bacterium RIFOXYB12_FULL_65_16 GN=A3K19_20240 PE=4 SV=1 +ENLLRADHVAFGLGSVGLAEAVDTVLGRCLAPNMALpAEKWQELRDALLPSRLELRPGVVLLHVHS---EDVDVPVVLWALSEAGFADSVTS-APARVLLVLLSPaslpPDQHLQMLSSLARTILAAPNPAAIAPVRSIEDLRKALTPSG +>tr|A0A1G0Z3R5|A0A1G0Z3R5_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_50_93 GN=A2X45_04290 PE=4 SV=1 +GKLMSPDRMVFGLEYENPEKAVKIILSNFLKGRSSDpESTASMLADELLPTALEIIEGTVLLHVHC---ENTDEPTVLLGTCSTGIPFSGID-NPAKSIFILLSPasdnPEEHLQILSDIARFALSMKNSDILHKAKNLPELETLLMIHK +>tr|A0A1F3F5U0|A0A1F3F5U0_9BACT Sodium:proton antiporter OS=Bacteroidetes bacterium GWA2_30_7 GN=A2046_13315 PE=4 SV=1 +NGLIEKGVNRIT----IGAKNISKIFKKEsdsSEI----------------------------------------------------------------------------------------------------------------- +>tr|A0A1V6BWV7|A0A1V6BWV7_9SPIR Glutathione-regulated potassium-efflux system protein KefC OS=Spirochaetes bacterium ADurb.Bin133 GN=kefC PE=4 SV=1 +FHFIENRNFYFNLNNLPIKNAFNYILKEKFGKTPEVlNELSDILSDIAINEPLTLLPGVILVHTHI---SQIEGHIIYVGVNRSGFDIPNIP-EKINIMLVLLTSteqpPEYHLNLLKEIVHLLKIENFVESVSKSNSFKEFEKTFKAGC +>tr|A0A1V4MXW7|A0A1V4MXW7_9BACT Uncharacterized protein OS=Candidatus Aegiribacteria bacterium MLS_C GN=AVO35_11095 PE=4 SV=1 +REIFPPGRVLLHMTETDGEEALRILIKKGYGQDEALeEE----CLRQLRESPLWLSGDCVMVHTHE---AGPPAPMALLATARNGFDLNGRT---ARILLLLLGTpgetPEEHLGRLAVVAGMLHGKETASAVVETSDYDTLSRMLSDNT +>tr|A0A1V5Q8H2|A0A1V5Q8H2_9BACT Glutathione-regulated potassium-efflux system protein KefC OS=Verrucomicrobia bacterium ADurb.Bin345 GN=kefC PE=4 SV=1 +SALLRSDRFFPGLDDMSVESAVGTMVRAALPQHPSVaDRLARQLADVAKQYPVEFAPGVLLLHSHA---GEWGEALVMAGVSRKGIAVPGLE-SPVKLLLLVVADrhqrNEEYLRVLADISRVLQRPGIIARLMDISSPVELDRVLADTE +>tr|N2ANE5|N2ANE5_9FIRM Uncharacterized protein OS=Eubacterium plexicaudatum ASF492 GN=C823_02279 PE=4 SV=1 +-------DFFRVDNRISFGELLIAIGEKMSPYSDCQEIIREDILKREQIASQVFAEfGFALFHART---KGVTRPAFSVCMTKDLGVFADAYFKGIRIVFIMLAPADDHIKingdIMGYISSMLIEDYEFIDIVVRGDKEEIRSALSG-- +>tr|A0A0V8QCG4|A0A0V8QCG4_9FIRM Transcription antiterminator BglG OS=Acetivibrio ethanolgignens GN=ASU35_03260 PE=4 SV=1 +-------TAIKVDNNIGFDELLLAVSEGLTPYHDRQSMIQEDIRHRESLGTQVFSElGFALLHTRT---RGVLRPNFSLCFTKDKGVFANPFFNGIGAVVIMLLPEDEHIRenreILGYLSKQFIEEPDFMDIILRGELEEIREEVSR-- +>tr|A0A099I5T6|A0A099I5T6_CLOIN Sugar lyase OS=Clostridium innocuum GN=CIAN88_15625 PE=4 SV=1 +-------LLHISDSDTLSQLLI--ESAEyIGKDAAAVEQIRADLQKRESMGPVIMQDlQFALLHAAT---SAVDTMEILLQYPRH---AWSAEAKNLKFAVVMLVNTQAGR-vrkeLLSLFSRGLVESETLLEAVCTQDIERIEEALSQ-- +>tr|C4G9M5|C4G9M5_9FIRM Putative licABCH operon regulator OS=Shuttleworthia satelles DSM 14600 GN=GCWU000342_00678 PE=4 SV=1 +-------CDYETDPKISFPDLVYQLADRVTESQAVAEKIAGKIQRREHLNSQIFPElDLALLHCRS---RMIREPVFISCRPSGDRSFADPDFKGIRAVIFMVMPEDEQLRmhmqILGQISASVIRDEAFVGAILHGDEELVKKELKK-- +>tr|G0VNS3|G0VNS3_MEGEL Uncharacterized protein OS=Megasphaera elsdenii DSM 20460 GN=MELS_0879 PE=4 SV=1 +-------QQFTVPASSTFAQVVHTLAAAATKGEEDTALLFDAIIRRECLNSQIFPDqGFALLHCRT---QTIRQSLFYTCVPDGP-AFEDDYFKGIATVLLLIMPEDEYRQvhtdVLGFISSSLVSDDAFYQAILGHDPEKIRCHLQR-- +>tr|E5VQQ7|E5VQQ7_9FIRM PRD domain-containing protein OS=Anaerostipes sp. 3_2_56FAA GN=HMPREF1011_00329 PE=4 SV=1 +-------RIYPADASEGKEEVLRKLLGHTDMGEKQKDRCLEAVMEREKDGPVALKDrKFLIFHCNI---PGNNTPVLMFFTLDHK-KGTHPDFQDFDKGALMIVDKKQDK-ktrdTLAVISEGFVNDERILESLEKKDPKALRCQIRE-- +>tr|E2SNI3|E2SNI3_9FIRM PRD domain protein OS=Erysipelotrichaceae bacterium 3_1_53 GN=HMPREF0983_02702 PE=4 SV=1 +-------HLHTTQQTTLSDILM--ESAQyLGRDEITAAQIREDLQKREAMGSVIMQDlHFALLHALT---PGVDHMEILLQYPQT---AWDEDLHNLKFVAVMVLHTESSR-irkeLLSVFSRGLVESEPLLHAVIAQDQQKIEEALSQ-- +>tr|R9LMQ4|R9LMQ4_9FIRM Uncharacterized protein OS=Firmicutes bacterium M10-2 GN=C815_01788 PE=4 SV=1 +-------VFVTVPSQMDLSQLIEEASVL---AKGSPSQIVKDLHRREELGSILIPElGFGLLHTKT---TGIEKPQVQFLWPDQ---QYFTQYENIEVVFVLLLPYEANS-ydqkLLSLISTHMMEDDRLREAVFAHEERHIQQVLSS-- +>tr|F5YNL6|F5YNL6_TREPZ HTH domain protein OS=Treponema primitia (strain ATCC BAA-887 / DSM 12427 / ZAS-2) GN=TREPR_2966 PE=4 SV=1 +-------TVIRINADCSFDYLFRFASDRFAPLAR--ETIYNKLMDREKISSQVIPDlGVILLHTRS---DAITIPVFAILKPD-GEKFKDEYFRGAKSCVVMLLPEAAPA-emtdLMGGLSSALIDVPAFLDAIHDGNEKVIKALLEA-- +>tr|A6LQT2|A6LQT2_CLOB8 Transcriptional antiterminator, BglG OS=Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) GN=Cbei_0524 PE=4 SV=1 +-------DLYTLSSEITIDEAMKFVSETIGGNEESKNYIYNDLMKREQVSTQVIKEfEFVLLHART---KGVEASKFILIKPD-SAQFDDEYFSNSKVIVVMLIPEDDPRGilAISSISSALFDDDLFLNDIKSGKKEIIQSYIEK-- +>tr|A0A140DX49|A0A140DX49_9FIRM Uncharacterized protein OS=Faecalibaculum rodentium GN=AALO17_20920 PE=4 SV=1 +-------VRIPTGTVYDPAVLIHEAACSl----QGDTEILEQDLWRREQLGAVRAPEeGFALFHART---GGTARIQAAILLPAGG-Q----YDNGLRGVLVTVLPADHTP-pmqqLLAQVNRQMGQDAGFRQVLLSGPAQAAREATDR-- +>tr|A0A1F9ZPP6|A0A1F9ZPP6_9FIRM Uncharacterized protein OS=Firmicutes bacterium GWF2_51_9 GN=A2Y20_03615 PE=4 SV=1 +-------DIVVLDPTIPMTKIFSTIGYRIGKDKKSGKLIVDDLRQREKMGSIHLEEeQVILLHAKT---AGVGSPICMVFRSN-ASSFQDPEMNGMKTIVVLLAPVNVNP-iiqeLMSRISAGLLEDPSFLFAIHREESARLRESIEA-- +>tr|A0A1C0BVU8|A0A1C0BVU8_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium MTC7 GN=A4S06_01995 PE=4 SV=1 +-------SIETLDYRSNKEDVMK-ACASmVSQRADHQEELVLALKKREALNTTVFSDlGLALFHGQG---AYVEQGVVKLIRPNHE-AFICEELSNIYFVFAMFLPENSNR-eqlqMLSMLSRKLIEDDNFYQACMSEPHAIVYQKLEM-- +>tr|A0A1H7HQY4|A0A1H7HQY4_9FIRM Mannitol operon transcriptional antiterminator OS=Pseudobutyrivibrio ruminis GN=SAMN02910377_01096 PE=4 SV=1 +-------HHLKIFPLTSFEELVNSLSSDITESPKAAVILASEIMAREQIMSQVFPEvGIALLHARS---RAVKECIVVTASCENGQELAGEGLNGVKAVLCMVMPLDEHRKenseMLGRISSAIIDDESFLSAIQNGREDTIRNKLQK-- +>tr|A0A1M7GWE9|A0A1M7GWE9_9FIRM Mannitol operon transcriptional antiterminator OS=Caldanaerovirga acetigignens GN=SAMN05660826_00492 PE=4 SV=1 +-------SLEK-VNTGTFEELLDAIGEKIKSKPGiiSVSEVKRDINERELKSGTAVPGaGISVLHART---VGVEKPFLGLFRLEKPLKmkSMDGGIEDVKACLLMLLPKKSSPKemeIMGRISAALIEEEGFAELLKDGADVEVIRSFIR-- +>tr|A0A1G7PWP0|A0A1G7PWP0_THETY Transcriptional antiterminator, BglG family OS=Thermoanaerobacter thermohydrosulfuricus GN=SAMN04244560_01438 PE=4 SV=1 +-------TYMTAkgeNSSQIIEYILKNLIDENLINENQKEQIKGRLLKRESLGKIVLPNkGFVIYHCTI---ENIDFPLVVVGKVIEEVKmkNLVGDYEKIRTAFLMVAPEGDREGieVLGDLSMSLIEREDLVNTLNEAQSqKEVKEKIKE-- +>tr|A0A1U7NF42|A0A1U7NF42_9FIRM Uncharacterized protein OS=Ileibacterium valens GN=BO222_07980 PE=4 SV=1 +-------KVVVAQKDSDPDSLIWQAARQf----EGNSSQIYEDLLRREKMGSVIAEDyGFVMFHAAS---SATKAPQFILLFPQEE-TFFAREYSSLHFIAAAIIPLEANK-yereNMSLISSSLIEEEAFLYSIISRDKKRIYDHLVR-- +>tr|A0A1Y4QPV3|A0A1Y4QPV3_9FIRM Uncharacterized protein OS=[Clostridium] spiroforme GN=B5E91_01050 PE=4 SV=1 +-------KLYILQHEISKQELIESSCKL----TSNDPLLISQILEREQRGSNVYNNfGFALLHVST---KLVNNCLIRIFKANQS-EFSSDELKNVKVVLLMLIPDNATD-iqkkIMSYISAQLIENNDFFNQLVNGDIEKIKEAFNK-- +>tr|A0A0Q1AV10|A0A0Q1AV10_9DELT Uncharacterized protein OS=Desulfuromonas sp. SDB GN=APR63_00030 PE=4 SV=1 +--------------------------------------MIDLACSREDLQETVLGKGVVLPHCRI---RGIREVLIIVGLSDQPFKWGKQE-DKAKIVILLISPavnPNLHLKALSFLAYQFRTKKDCIDVNSKNMEELVKEVILEKR +>tr|A0A1F2Z7S3|A0A1F2Z7S3_9PROT Uncharacterized protein OS=Alphaproteobacteria bacterium RIFCSPHIGHO2_02_FULL_46_13 GN=A3B66_07455 PE=4 SV=1 +---IDFTAAHFGVKGDNPLQVIKNLAFTISrDTHNPSTILHSQLDGLLKNSMIGIGEGVGVFDWVS---KDIDTPYIMCSMLENSVTFPSVDDKSLDIILVLISPEKNgplHLQSLSRLTRMFRDAQFLASLRSVHSCDGMLSILCHD- +>tr|A0A1Y3Y046|A0A1Y3Y046_9ACTN Uncharacterized protein OS=[Collinsella] massiliensis GN=B5G02_00860 PE=4 SV=1 +-DSVPRRFVRAHIQAPNWESAVRLATGPMLQAGAMTEEYLQGIFDLSRRYQQFgvICPGLCMPHANA---DPDNELSLSLVTFERPFDVDMGQEHrvPIKVMFVIAPVDgSRHSRIVDELITLCDSFpKFVDDLAAAESSDELYRSFLR-- +>tr|U4TTY7|U4TTY7_9LACO Uncharacterized protein OS=Lactobacillus shenzhenensis LY-73 GN=L248_0506 PE=4 SV=1 +---------------------LTAVGTWLAKQKVAPnsQQFMETVLTREQAGSTSIGGGLMVPHYMQ---PGLSPARLVAVPIHAAESWPGLDGQPIRLLLITCFDPDQPQPAFQALLRGLASPTAAAKLVRQPDAG---------- +>tr|A0A0Q9VZJ9|A0A0Q9VZJ9_9BACI Uncharacterized protein OS=Bacillus sp. Soil768D1 GN=ASG99_18470 PE=4 SV=1 +---LHPSYILIQPKRLENEHSFEEMLAK-----MIDGTTSYKGfIEKKIVSETKVNNQFSVFLIDQ---KVVNETAVGINIIK-GVTPTDSK-----LEIVIAFKdRLSLNELLTEVFSLSIHKVVFERIIQAGTLSELEQILI--- +>tr|A0A0D7X175|A0A0D7X175_9BACL Uncharacterized protein OS=Paenibacillus terrae GN=QD47_13100 PE=4 SV=1 +---LLPELCVAGAKVSSREEAVANLTNRMHEMGFINSEFEATVFRREALTPTSLGNGVAIPHGEV---DHVLQSKIAVMSIPEGVDWGGEQ-----VyiVFLIALkLdDELSaKEILNDLYNLLDSDYNMNRLRICQDHQRLYELLA--- +>tr|D1AMM5|D1AMM5_SEBTE Transcriptional antiterminator, BglG OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_2754 PE=4 SV=1 +---LNKRYIQIENEIFSEKTNVKKLIKK-----IINENY-LEIrNAKEYISEIHINESFSVYLIKK---DIVTKTCVGFRIKS-SA-AGEYK-----ADIIIGVKdNDEIhRQLLREIFELYNNKELLKKICFCRNTNEISELIN--- +>tr|I9NQ37|I9NQ37_9FIRM Transcriptional antiterminator, BglG OS=Pelosinus fermentans JBW45 GN=JBW_04352 PE=4 SV=1 +---ISATDIYINTEDAFII-----NDLE-----HNNGQ-------KLSFYNVGFGREIQILLAGN---SNVKRFAIQIMNNT-E---DGNC-----IKFYILNPDYEHvKNIVVEIYHLYEAKNEMNYLLECTRTIDVQRFFN--- +>tr|B6G219|B6G219_9FIRM PTS system, Lactose/Cellobiose specific IIB subunit OS=[Clostridium] hiranonis DSM 13275 GN=CLOHIR_02181 PE=4 SV=1 +---FS------KYEVLKKE-----VLHD-----Y-------------NIPKFEFKDGLNIYINKN---NN-NK---NKVFIG-K---QNKK-----IEIFIDSNNDSYiKNTIIKTYSLYKDKNIDSLFME--------------- +>tr|A0A1R7D8P2|A0A1R7D8P2_CLODI Transcription antiterminator OS=Clostridioides difficile GN=licR_3 PE=4 SV=1 +---YLEDNIYFNFDVMQME-----SLIG-----VDLGS---------KYKSISLGKDLNIYIHNQ---SKLNK---GIMNVN-N---INRT-----IDIYLETSNQSFlKNILMEISNLYRQKSYINYIIDCKSKEDIKILFK--- +>tr|A0A1M5BY17|A0A1M5BY17_9CLOT Transcriptional antiterminator OS=Lactonifactor longoviformis DSM 17459 GN=SAMN02745158_03861 PE=4 SV=1 +---LPGGHITFGY---------------------WNGASARG---QKICESYLLPQCLAVVWKRK---DEKTE--VF-LTV----DTENEM-----LRI-DLLPgRVEHqKELLRELYRLTLEEKNVRAITRCRTQEEVQKCLR--- +>tr|A0A0Z8FYK7|A0A0Z8FYK7_STRSU BglG family transcription antiterminator, PTS system IIA component OS=Streptococcus suis GN=licR_3 PE=4 SV=1 +--------------GNTEEEVIRELIYHQIGKNAQAEQLIKEVADREKITTTSLAHNIAIPHTLS---KDLKCSSIIVGIHGKGILWGDKQ---VQLIILSLFSdkDKAGGEIFRKLYHFATNRDIVEKTIQERTTYYLVHYLEGDS +>tr|F4PG21|F4PG21_BATDJ Putative uncharacterized protein (Fragment) OS=Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) GN=BATDEDRAFT_29046 P +IFDFEPQHILLTEREMSWKEALEMALLPMKRRKSVTDKYCMKVKELFQNEGDRmmIGPSVYLPHASTN--NGVLYEDFSILLCKHKVEAPNGE--LIKMMIVLAPEDgNNHVSTLLFLNEIFLDEVKADKISGAETEQEFIELIHSFK +>tr|A0A0R1WUZ3|A0A0R1WUZ3_9LACO Uncharacterized protein OS=Lactobacillus kefiranofaciens subsp. kefiranofaciens DSM 5016 = JCM 6985 GN=FC93_GL000530 PE=4 SV=1 +--------VRYDLNEDSYYKSVKELVELLSKDNELTLDFYQRWTERKKKSNNVISNGIAIPHAVDN--SGRERILLSFGIIKKRVVYKKTK---LRFIALLGIPenlDSSLVKATSELYDFVsmivRNQVLLENAEKYNNERSFIQMLEG-- +>tr|A0A1Z9M1E3|A0A1Z9M1E3_9BACT Uncharacterized protein OS=bacterium TMED198 GN=CBD58_03510 PE=4 SV=1 +-DIIDPNNIIVPIKSTIKEHAIQELLRHMEKNGNLSstAKLNDFINSQEKAFSSAAGKGVAFPSCGS---IEVENVIAVLGVSKNGVAFNAPDGLKCHLILLTLSSkkdPTKRRRLVHMFQDMISNIEIKYSMMEDGSVESIHNTI---- +>tr|A0A0H4T8B8|A0A0H4T8B8_9DELT ATPase P OS=uncultured delta proteobacterium Rifle_16ft_4_minimus_37851 PE=4 SV=1 +---LSA--ISLDVKSkdhdGVLTE-MSSLL--fKDIPGAVGDkTFCDL-KEHESMEGVLFGTNSAIFHCLS---EGVDDVMIAVSISGRGIPHPKKkkyR---INIFFLIVSPmkeSGTHLRIMSRVEGFLLDR-SFRHAVLSAKTADEVKKAVKRE +>tr|R8ZRM8|R8ZRM8_9LEPT Putative calcium-translocating P-type ATPase, PMCA-type OS=Leptospira yanagawae serovar Saopaulo str. Sao Paulo = ATCC 700523 G +---LNVDSIQILKDVkhwGDIQIALMKKIPELEIQKEIQYRFH----SIPNHTFETIGDQILIPHFRS---ANIKTPELFLFILPEGIKVGEKK---IQLVLFQMIPeqlPSLHLRLLHGLSSLLPQ--IFEKLMLCNQAVDVLSVVQLGE +>tr|A0A1F9JY90|A0A1F9JY90_9DELT Metal-transporting ATPase OS=Deltaproteobacteria bacterium RIFCSPLOWO2_12_55_13 GN=A2W73_11970 PE=4 SV=1 +---LKPEKIVIGLK-GELPQVLDRLFNRssfPDRVEEFRSALV----KGNSNPYSYIGNDIAVPHVRL---EGLSRPEMILGLSRAGMRLNGNV---VKILLFFATPaeqTEEHLQLLQRLTSLLPA--IKDELLAQRDTTSALKIIAKGE +>tr|A0A1V8ZJY0|A0A1V8ZJY0_ENTCA Uncharacterized protein OS=Enterococcus casseliflavus GN=BH739_12590 PE=4 SV=1 +---LLNSHVIRIDQKCSWEHSLRLAGKVLTHNECIEQSYVEEVVENVKQNGPYivISEGVALAHANNR--GNVHRSTISLLTNKQKISYGSEDYFQVTYVFFVALVrSEEYLEIVEDIM----------------------------- +>tr|A0A0F4LNM5|A0A0F4LNM5_9LACO PRD domain protein OS=Lactobacillus kimbladii GN=JF75_02650 PE=4 SV=1 +--ILPERRIAFENGTYSWQESVKVTGRLLEKDHIADEKYTHKMCMQIEKYGPYmkIMDNVMLLHAKPDNPTKFSVPGMSLVCFTPPVKFSNDI--KAKYVFSLYAPNsNSQLKALTQLTEIFSNRFLLEKFEHAENAPTFIKLFDS-- +>tr|Q034D2|Q034D2_LACP3 Transcriptional antiterminator, BglG family OS=Lactobacillus paracasei (strain ATCC 334 / BCRC 17002 / CIP 107868 / KCTC 3260 / NRRL B-441) GN=LSEI_2725 PE=4 SV=1 +-----------NPANMSYEDVLRATLQGDSDAGIVDPGFIDRLIKHESTTKFVLDNGVAIPHAIAD--IDHDRLFLHLSVLKHAITVGGKS---VSYIFVIGIPrvlGKRALEDLSMLYDLLfllaVNETAMNNLRKISGSQDPLTVVTEG- +>tr|H1LIY2|H1LIY2_9LACO Uncharacterized protein OS=Lactobacillus kisonensis F0435 GN=HMPREF9104_02574 PE=4 SV=1 +-----------------QEDALTELERAVTQQHVIDkpiDQLVDDIKKREQLGSTEIYPGIMMPHINEP---YVNQTTVVVTRFTQQAKLLGHSGIRAAIFVLT----NGATDALAEFMHLLVDPRPFEYLLD--------------- +>tr|A0A1M7LKX7|A0A1M7LKX7_9BACT PTS system, nitrogen regulatory IIA component OS=Fibrobacter sp. UWR3 GN=SAMN05720472_2228 PE=4 SV=1 +----------------------------------------NSLSERVKQGI-YMGDGLLLPHTRI---AGLERPLMAFCVCPAGFtGIEIRGGEKAQFMCVLLSPAESamaHTQAIAGVAKLILDPEWKARALAAPDDAGVKALF---- +>tr|A0A109RDP2|A0A109RDP2_9LACT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Aerococcus christensenii GN=AWM71_02255 PE=4 SV=1 +------------------------------------------MREREELGSVQIGSYTVMPHMEA---EEIPSSKIYLFLLEKPFYWNDQASQIrIILTLFICPKKDSHKEKIRQVIRHFAEPHIEQKLLNSKDNHEVFNLLTN-- +>tr|W7CEE7|W7CEE7_9LIST Frv operon regulatory protein OS=Listeria weihenstephanensis FSL R9-0317 GN=PWEIH_10278 PE=4 SV=1 +-----------NAPEEDWNTIVQGICRELEARDILSSDEAMKIQEREQKGNNLVINHLALPHCTT---QRNQAFFAVFVHLAEAVLVDGTL--VHNALVACVNPNvSTELKVFSYLYYVLNEHDS-EDILSLTDYAAFIDCIEG-- +>tr|A0A0C1YY96|A0A0C1YY96_9BURK Phosphoenolpyruvate-protein phosphotransferase OS=Burkholderia sp. MR1 GN=BurMR1_1444 PE=3 SV=1 +MAPVSGVMVQLESVPDPVF-----AQKMAGDGVSIDPTSDELLAPlsgtvtqlhRATHAATiTGASGLQVLIHIGLDTVMLRGEGFTPLV-KEGDTVTT-GQPLIRfdpVIVGARAVSL-----LTEM--VIANGELVTRYMPAtglvtagKDVALSVEFVGGKS +>tr|A0A1Z4PS59|A0A1Z4PS59_9CYAN Phosphoenolpyruvate-protein phosphotransferase OS=Scytonema sp. NIES-4073 GN=NIES4073_16110 PE=3 SV=1 +FNKVDGVVVvGIVIVSHskklaeGVRELAaqmvQGKVPLAVAAGIDDPENPLgtdAMQVYEAI-ASiYSDEGVVVLMDLGSAVM---SAEMALEFLPEELRDKVHlcEAPLVEgaiaAAVAAAA--GSHIQQVIAE----ARGALVAKATQ-lgVTHNLTPNPSPQAE +>tr|A0A212LI09|A0A212LI09_9RHIZ Multiphosphoryl transfer protein OS=uncultured Pleomorphomonas sp. GN=fruB PE=3 SV=1 +KPLLAPELTRLKAAPADKEAAIRQACALLADAGYIDPAYADSMMRREAVAETYLGQGVAIPHGMNADRGLIRHNGLAILQIPGGLAWNE--GQIVKLVVAIAAQSDDHIAVLRRLTRLFQDEAALEALFVTDDPLAIIAALDETA +>tr|A0A179YFI7|A0A179YFI7_LACRH PTS system sugar-specific IIA component OS=Lactobacillus rhamnosus GN=PY91_05325 PE=4 SV=1 +-------------------------------------LVQQLVTRREREGETYIGYGAVILHLIS---ERVPQTTVLLVKSQTPLDWTSryaNQIHHVNKFVILAISPhDLDGASFRPVMEELADEASINQLFEME------------- +>tr|A0A075LLW0|A0A075LLW0_9BACI Uncharacterized protein OS=Terribacillus aidingensis GN=GZ22_14515 PE=4 SV=1 +----------TYQMQ---ADLFSQIDQHAVDHTVINkhGTLASLLRQRDELGGMGIpDTRMALYHSRS---TEIEQPAFWMMALSSPIMIKGMDNQVmeADRLFILAAPDNLPLScyELfSKISILILEEhIQHMIRSA--DQEALSKELAQL- +>tr|U1EDY0|U1EDY0_9STAP PTS lactose transporter subunit IIB OS=Staphylococcus sp. EGD-HP3 GN=N039_10140 PE=4 SV=1 +----------VNIEYTDVTEINDYLTTHLYQQQIINdvQSFADELQQRSLTQNYILdPYPIAIPHLKH---RLILRPYILVTILNQPMEVIDDQNDKhtIQYLLAMFAPEDDFSAEIiSRFSSAFANHlTELETLML--YPERIRELVKQS- +>tr|A0A0D6XPQ9|A0A0D6XPQ9_9STAP PTS lactose transporter subunit IIB OS=Staphylococcus microti GN=TP70_11000 PE=4 SV=1 +----------IIVSTAHCQNLDTALAHYLAELKVINntLEVSHLLKQRNQTQNFSLaPYPVAIPHLKD---KLIVKPHFSISKLAQPITSPD----QppIHYVVCAMLPENSQLTPLvSHLYSYITEHlEDIDTWMS--DQTEVEHALKQQ- +>tr|A0A178PK70|A0A178PK70_STALE PTS lactose transporter subunit IIB OS=Staphylococcus lentus GN=AXY37_01960 PE=4 SV=1 +----------MIFEQRKVTNLTRYLVQTLTKHHVLEnsNDFIEKFEQRTALQGFALtGYPVAIPHLSD---ESIKKPQLIITELIKPLSLKTIENKEqeVNWLVSMFIPANSEQGQLmSEVSSLITEHlDDINHLLN--DRVLIENTLKSF- +>tr|A0A0M2SN61|A0A0M2SN61_9STAP Uncharacterized protein OS=Salinicoccus sediminis GN=WN59_05685 PE=4 SV=1 +----------AFTESDTPLGTMDSVRNMLAEHSSLErhaaLDTVRRLAERFKITGHVIgEAGFSYPHIKS---PFIRSHQLIIVHNSAGITDRNYNGDAvtVNYQIILLVPEESLISDLiSEISVLLGEHhEDIGSLLK--EPSMLDVLFKNY- +>tr|A0A1S1F3H9|A0A1S1F3H9_9STAP PTS lactose transporter subunit IIB OS=Staphylococcus sp. HMSC070A03 GN=HMPREF2798_12590 PE=4 SV=1 +----------IYVEDATITNWQDYLAKRLAKHKSILskSQFKQVLKTYAEDRSITLaPYPIGLPHLKH---ALIVKPMVMITRLKQPLTIVE-QNQEhtINYLISMFLPEDNPSSPIvSAISEVITCNlHRIDELMQ--NPNEIIDEMKKA- +>tr|A0A1Q9ID52|A0A1Q9ID52_STAPS PTS lactose transporter subunit IIB OS=Staphylococcus pseudintermedius GN=UH47_12840 PE=4 SV=1 +----------FEVFHTDLTDWSYDIAQHLYHKKITHdlIAVQQLLKERHDKQSFVLsPFRVAIPHFIS---AHVEIPYIGVWHLATPYDFDE----GltVDTLFCVFLPEDTHLQPLvSEIYSQLSLAlDEHNDALT--DAEHIEQWIKQS- +>tr|A0A1W7A967|A0A1W7A967_9STAP Transcriptional regulator MtlR OS=Macrococcus canis GN=mtlR PE=4 SV=1 +----------IQFAVMEDEDFIAFAA--SKMQDKVNdlEAFQEALSYRNHLQGFLLtDSTIAIPHIVH---ESIHTAAIILAHNKNGVELKNMDGVMshAHYLVYMFLPEDTLLRPLiSEMSLLVMEYvSSPEKLFN--DEPFVIEYMKQA- +>tr|S4ZQ50|S4ZQ50_LACCA PTS system, galactose-specific IIA component OS=Lactobacillus casei LOCK919 GN=LOCK919_2816 PE=4 SV=1 +MTDLITPELVYFLNTPTQAAFFKTISTTLVDQQIMAPAGKEALITREQTFPSGMQlnevadglPNIAIPHLEG---ELVKQTRLVVVHFAIPVAFKDLADAsrilPVNWVFMLMNAEpQKQPERMAQLIRALTQSpaAQLKRLFAAKKAAQVARL----- +>tr|A0A0E2BMB0|A0A0E2BMB0_LACCA PTS system mannitol-specific IIA component OS=Lactobacillus casei A2-362 GN=LCAA2362_0629 PE=4 SV=1 +----------IKLGQeaKTKEEAIRQA------GQLLVdnGNVEPAYIDSMldrnrdvsvyMGNFIAIpHGTeagMKYIKSTA---ISIVQYPWGVDWsddpadenlVTVVFGIAGLNGEHLkl----------------LSQIALYCSDVENVQKLADAQTPEEIVNLLKE-- +>tr|A0A178HEG7|A0A178HEG7_9LACT Uncharacterized protein OS=Aerococcus urinae GN=A1D21_03560 PE=4 SV=1 +----------VNNTGkakLDLKSLLDQQIGQLR-GQQVGdsQQVSEAVMRRFEESAIGIpHSGIGLFHTSH---AEVFQPYFVIYDLAEGYPILGMDHQMMtlrRLLLLLAPNPltPWLQEVMGAISSSVIENDANLSLYDRGDEGLLKQLLNN-- +>tr|U5SAV6|U5SAV6_9LACT Transcriptional regulator OS=Carnobacterium inhibens subsp. gilichinskyi GN=Q783_09575 PE=4 SV=1 +----------VVGN-QPLEETLLWICRQLQDIGVLIeaENVQQKLIERVNIAPVGIpGTQMGLFHVRN---IDVASSYFGIYELEQEVPIVGIDRKDMvlkRILIMVAPYPlnVIERELLGLVSSMVIENDSTTALFDKGEEEAVRKKIEK-- +>tr|A0A0H4QND6|A0A0H4QND6_9LACO Uncharacterized protein OS=Lactobacillus ginsenosidimutans GN=ABM34_12515 PE=4 SV=1 +----------IDNRMFNLQQTLLLLSRRLRPE-FVSnpDQVATALYQRMQKAPVGLpNTTMALIHTTN---EGVRRPFFALYDLTNPILIKGMDYKSMnlqRCLFMIAPKDlpQFSTDLLGSISSSIIDNELNLRTYQQGSPEEIKQLIAK-- +>tr|A0A1F1QMI0|A0A1F1QMI0_9LACO Transcriptional regulator OS=Lactobacillus sp. HMSC08B12 GN=HMPREF3168_04975 PE=4 SV=1 +----------IGSQGMDMNAVLSAIVTAVPDE-YVKdrLEVAQRLKKRLDLAPLGLpGSHLALLHTRT---RAVSKCFFAIYDLAEPIAMTAMDQSKImvkRQLLLLAPEDlpEASANVLGMISSFLVMSDQTLQLFESGNCQEIAAAIAQ-- +>tr|A0A1Z2F6I6|A0A1Z2F6I6_LACCA Uncharacterized protein OS=Lactobacillus casei GN=BGL52_14505 PE=4 SV=1 +----------MTAPVTTIAAAIDAILSRLPT--VVAeaPVVKEALLKRLELAPVGIpDTGLAMIHTSS---QGVTTPYIGVFDLTSSLPLPAMDMGTIqlqRILLLLTPNPvsQETLTLLSAVSAKLVASPADLRLFEKGNYSQLYQVMTE-- +>tr|A0A174WWS3|A0A174WWS3_9CLOT Putative licABCH operon regulator OS=Hungatella hathewayi GN=licR3_2 PE=4 SV=1 +---LKPEFGIFGLEGKSREEVMENLYRCLAARGLIAteLDWKNAFRANE------VGNGIAHIQDLG---RILKNAGCYVCILKTPILWEQDI---IKVLVMIKTKrdGDKNLSLLcRIVSNWASSPEKVEHFLKSQSYDVFCGDIKS-- +>tr|A0A1Q9JT30|A0A1Q9JT30_9FIRM Uncharacterized protein OS=Anaerostipes sp. 494a GN=BHF70_06835 PE=4 SV=1 +---FSPASICFDKKYDSWENAAKAAGILLSLEGSIKESQINEVIEYLKSNGKNaiLCQGVIIAFLERE----VKRESASLIRLKELVLYTGEH--PVFYFAVFGIQDgQSINHIIYNLVSLFGNKELRTEIDKVKTPEEMFAVMREME +>tr|A0A1V6GWR2|A0A1V6GWR2_9BACT High-affinity Na(+)/H(+) antiporter NhaS3 OS=Verrucomicrobia bacterium ADurb.Bin070 GN=nhaS3_1 PE=4 SV=1 +---LPWQSVSLDLAPADQAQALSLLLALCARSGAVSalEELHAQMQARAPLIPERIGDDVALFTVES---PGVFRVALALGVSAQGVA--CACGSRCRVCVLALYPPsaaEDMARVKAALARALDAQGL-AALLAAQSSSEAREALLR-- +>tr|A0A202DG93|A0A202DG93_9BACT Uncharacterized protein OS=bacterium E08(2017) GN=BVX97_06030 PE=4 SV=1 +------RKTVIDMSKVEQEKAASLSqylipELICPDlkggtkteviqellnlldeRKLINnmRRARADIMNREKQMSSGMAHGVAIPHART---DAVSSLVCAVGVKRDGLDFGSLDGEPARIIVLTLSPKdtaAPHVRFMAMISRALNDNGR-AMVLEAREPGEIMTALLS-- +>tr|A0A0R2KVG1|A0A0R2KVG1_9LACO Uncharacterized protein OS=Pediococcus stilesii GN=IV81_GL000506 PE=4 SV=1 +--------------------------------GINAKEALASIEKRNLSGTTKIEKDFYLPHVET-NAQ------------EQGILLIHyydlnNT---KQTALVMVVNSRNPDKKLEEIMGILLNSKNINKMKHCNSNEEFRRLIQE-- +>tr|K0DBV4|K0DBV4_LEUCJ Uncharacterized protein OS=Leuconostoc carnosum (strain JB16) GN=C270_02615 PE=4 SV=1 +--------------------------------NLVQHVVEQAIIQRNQLGSVQIAPDIDLPHVVLPNLS------------YQGILLLRSW---DKLHLIMIIDNQYPSKNIITVLNFFLSDTGLKKLRTIITQQDLTYIIKE-- +>tr|A0A0R1J1X5|A0A0R1J1X5_9LACO Transcription regulator OS=Lactobacillus tucceti DSM 20183 GN=FC72_GL000956 PE=4 SV=1 +----PNNYLNLANSNGNYLSNLKIGLSEFKNRDLLSDDLIQTLINREEAGNQLIIDGvIAVPHATAN----IKFGNIFAIKLDNPVNLNNNL---INLILNVVINDqeEESRQIFSYLYKIFHNTPK-EKIKQISSYDDLLKILN--- +>tr|A0A069EWY9|A0A069EWY9_9BACL Uncharacterized protein OS=Exiguobacterium sp. AB2 GN=DI14_12620 PE=4 SV=1 +-------------DQMTFDRAVQAIGLELEGRGIVDGTFTRAVLEQERTIPSGVA-DVAVPVAVIDvPRHVTREDGITLLHLNHPFDVLSITGEPvrAEMLFFVTATTEARREAFHKLMdDLLMDDETLQALAHIKSRSGLYHL----- +>tr|A0A1G1SII3|A0A1G1SII3_9BACL Uncharacterized protein OS=Exiguobacterium sp. SH31 GN=A6395_12230 PE=4 SV=1 +-------------DQPTFERAVLAIGLELEGKGIVDDTFAQVIIEQEHTIPSGVT-DVAIPVAVIDvPNRISKRDGITLLHLNRPFDMRTIAGELvcAEMIFIITATTDEKKQTFHKLIdDLLMDDESLQALVHVQSRTGLYHL----- +>tr|T1KJ99|T1KJ99_TETUR Uncharacterized protein OS=Tetranychus urticae PE=4 SV=1 +---VTETKVILDVPETSVHRILEVGLLKIFGRAFDVNQFRSVLCISEDV--PKLKetfQSLTYDHngffafdqswicvtGSL---PFLSQRLTGIIRLDSPVNFGDNA-AEIRFIIMVLVPikekgTKNAFETGRTFATLFTSAEFRNNLLQAKKASDFLAVIRRR- +>tr|A0A0R3X0G3|A0A0R3X0G3_HYDTA Uncharacterized protein OS=Hydatigena taeniaeformis PE=4 SV=3 +---IKGATLLLDLEASSIEEIIHDMLEAVFTEtpghlnhaattptgisgihrhfltpnhsphgstlecedshnatnassinnsgghvhgrshtltrttgsglfatttklsalnkDELIEEAKKALLLEIKQNdlaYRRLSktiKSVSFHEnegitmdqswicalCSL---KNIQKRYLALARLAYPVNLGRSN-EGTQIILLVISPqkekkTKCEIELGRTFATILSDLEFRRQLIYAQDEEEVKALLCAR- +>tr|A0A0K0FXR3|A0A0K0FXR3_9BILA Uncharacterized protein OS=Strongyloides venezuelensis PE=4 SV=1 +---ISNASIIINEESTSLDKIINNLVCEIIFKndlknLSYVEDIREKIFNHSNYLevnkyleLLHLKnliTSAQII-genifidqkcltiyCDI---EKVSHHYVGICKLQSPTNFGTFL-ESLQYVSFILGPssskpIKTPFEVGRSVSTILSHESLRLDLEDITTKEDFISKITEY- +>tr|V4CPR9|V4CPR9_LOTGI Uncharacterized protein (Fragment) OS=Lottia gigantea GN=LOTGIDRAFT_136234 PE=4 SV=1 +---LKKTVLLLDLEKTNMDEIIDEIVNKMLKSestkNSSLEQTKSAIFTHDFGMlhfsFHQMSrtlQSTSISEgggfdydqnwvltmCSV---PSVQTRHVGIARLSSPANLGNTA-QEVYFVIVILTPtkekgTKNELEIGRTFATLFADSNLRLRLLNANTEAEFNQVLEQQ- +>tr|A8XQS1|A8XQS1_CAEBR Protein CBR-ABTS-2 OS=Caenorhabditis briggsae GN=abts-2 PE=4 SV=2 +---IQRGIIHRNMDHSHI----HTILLTLFSElssqfpreRFDLALFKNAVFSVSDRDarAPRLHqklQSY--SGtdffdvnqtwivtqlvilsfslflinrfsAQL---DGLKQSHMALATLENATNLGLEM-EEARIVVLILSPsyekhTKSAAEIARTFGTLLMNDSLRQSMTDAADDDQIRDLLTDS- +>tr|T1JUK2|T1JUK2_TETUR Uncharacterized protein OS=Tetranychus urticae PE=4 SV=2 +-----QDVMNGD------sDDKMDEiELENTGMKeetkaKLDLDEIMGSIFCEKES--RVIInriQGVLESNssptvfdqswvcilGSG---VSVKKHMIALGITEAPLNLGHGM-EQIRFILIILTPtievsagikkhTKSSYEIGRTFSTLLMHHSLRFDLLDSSK-ESIKEILTDK- +>tr|A0A1S3IGM1|A0A1S3IGM1_LINUN sodium bicarbonate transporter-like protein 11 OS=Lingula unguis GN=LOC106163546 PE=4 SV=1 +---IENAHVLLDVHESRLDDITRNMLSTTFGSsaEFDTDKLMDAIFTHDNV--HCLSktiQGTSDLGgggfdydqswvvvlGLI---PELKSQTIAICSLKHAANLGHTS-QEVKFVIYVLADesgSKEALVTGQALATIFADLRFRQELHDVHNVAGFKQLLLEH- +>tr|H9G8A5|H9G8A5_ANOCA Solute carrier family 4 member 11 OS=Anolis carolinensis GN=SLC4A11 PE=4 SV=1 +---LARASIILDETATSLDDVLREMLKHFAEDsdnaepscnfdki-------MSTLFTDSGTPregnVHLLSdtiQGVTATVtgvqyqqswlcimTTL---TTTEKKHLYSALLTPKGTQGGSH-AHIKVMILQIKPqnimlYNKltekAVQYTVTLCSIYYIYKFRTKTINFKVVQGIKSMMKHK- +>tr|A0A1Z8M876|A0A1Z8M876_9PLAN Uncharacterized protein OS=Rhodopirellula sp. TMED11 GN=CBB71_15795 PE=4 SV=1 +---ISQGSCLLNLDATSMDQVVESSIDILIQSg--RLPEYQRELVIEGVHQrEQMVPtaiGSAS---avphFYD---DRIEKPLMVFVRLKRGVNFGAPDGIPTRYVFLLIGPtdqa-ASHLDSLASIARMMSDNVCQFELTYAESVEDVLGVIERH- +>tr|A0A1U9YRZ3|A0A1U9YRZ3_9BACL Uncharacterized protein OS=Paenibacillus larvae subsp. pulvifaciens GN=B5S25_17975 PE=4 SV=1 +----NSEHTFQLSRISSLDEALNLLAAPLLQKNYIQASYMAQIRKEiVDEQKWYfIYPKVLLLHTDYR--YGSFKPGVSVLYTASGLIMKDEPFLEAELIILLSTDEKmTHVPLLFDLDKLMQS-SFLSELAKGVLMETAFYHA---- +>tr|A0A0Q1ACL1|A0A0Q1ACL1_9DELT Uncharacterized protein OS=Desulfuromonas sp. SDB GN=APR63_01185 PE=4 SV=1 +-----------------------------------------------------MGGGIAFPHGRI---NLIKTPLVAVGLSpKKGIPFPSKSGSRkisTYLIFMLLLPssdypvniagkSKQYINAISSVAKFLRTIKSKKLVKSFKSEPDFLNFVEKY- +>tr|A0A0C2D533|A0A0C2D533_9DELT Sulfate transporter family protein in cluster with carbonic anhydrase OS=Enhygromyxa salina GN=DB30_05862 PE=4 SV=1 +---IPAENIELRSSAATLDEVIELAAPRLASLvGLDTEPVLEALSAA-SDGHVPLGDGVSLPHAAI---EGIERSVVVVVTTTTPLTIGDDQ---TDIFFVLLSPagdTAEHLRSLAHIGRMCHRSPLLDELRRAPKPE---------- +>tr|A0A0R2HU27|A0A0R2HU27_9ACTN Uncharacterized protein OS=Atopobium minutum GN=IV72_GL000271 PE=4 SV=1 +----KENYVALQTKGLSYEATLTKGLDMLVSCGRMSKEEATATLARELQADRLEFNGVAVPHCVTK--TPSHSFRLFAICPTTAV--PTPQEAIKLILIVFASKHqDDKNTIFSYLYSTLSSQASIE------------------- +>tr|A0A133XVQ3|A0A133XVQ3_9ACTN HTH domain protein OS=Atopobium deltae GN=HMPREF3192_00640 PE=4 SV=1 +----EQNFCRLAVVgdadvadcvaavglNASYEQLLKRGLDMFVQRECMSKTEARKVLDREQSSDRLYFKGVAIPHSVTE--TYASQFRLFAIAPDRAVFadaNTAPDKPISLILVVLASQHlQDKNSIFSYLYTVLNTQAQIQ------------------- +>tr|A0A1Y4BGW2|A0A1Y4BGW2_9ACTN Uncharacterized protein OS=Olsenella sp. An293 GN=B5F85_03225 PE=4 SV=1 +----EESYFHLSVEpGQVYLSVLEDVLGRLVDEHRITADEADLIRQRERAGKRLNLGGIAFPHAITP--VESDEFRLAVACLDEPV--TDTDDRIELVIVVLASQSqADKSSIFTYLLSVIEDARARG------------------- +>tr|K4IJV5|K4IJV5_BIFAP Putative PTS IIA-like protein OS=Bifidobacterium asteroides (strain PRL2011) GN=BAST_0019 PE=4 SV=1 +---------------ESMHALFVCICRHLQSKGIIRsvDLLAKELLAREVSGSTVIADHLANPHAQGP---FVDECVLFYLRLSRPVpKWDGLH--EVSRVLLTLIPQNpsmEDLQYLRDLYRRMGGERVLDLL----------------- +>tr|A0A0Q0WEC6|A0A0Q0WEC6_9DELT Uncharacterized protein OS=Desulfuromonas sp. SDB GN=APR63_02155 PE=4 SV=1 +-DILKEQNITICQEKMDYPQVIQCLIDLVDIDQDQQQQIVNFINSNEKLTSSTLGKGVMLFKAWP---VQIQSTHCSLLIFPQGCEIEAFDDQIITICGLIAAPqekEQQYHQLLISWLRMLNESSLRDDFIECDTPQEVINLIREEE +>tr|A0A1G3Q9J7|A0A1G3Q9J7_9SPIR F0F1 ATP synthase subunit alpha OS=Spirochaetes bacterium GWF1_41_5 GN=A2096_16900 PE=4 SV=1 +---LAEKCLIIDYkGKPSIRNVFKSASAALAEslQNTNEKEVLQKLLEREQSSSTALSEFMALPHIIT---GGTSQFQMVMVRAGAGIKFTDQH-PSVKALFFLAGSmdqRHFHLVVISALAQIVQHPSFESSWTQASGSSELRKIVLS-- +>tr|A0A0A2W1K0|A0A0A2W1K0_BEABA Phosphoenolpyruvate-protein phosphotransferase OS=Beauveria bassiana D1-5 GN=BBAD15_g233 PE=4 SV=1 +-----PDVVFAekivGDGIAIkptGNKMVAPVDGTIGKIFETNHAFsiESDSGIE-----LFVHFGIDTVELKGegfkriaEEGQRVKKGDVVIE-FDLPLleekakstltsVVISNMDE-IKELIKL-------------------------------------------- +>tr|A0A1Y4CF67|A0A1Y4CF67_9ACTN Uncharacterized protein OS=Olsenella sp. An285 GN=B5F79_09945 PE=4 SV=1 +LDLLGERCFGVCDEVEGMDELILLGGGLLHKAGLCDEEYPRQMVSAAHCFGPLttilIAPGIIMPHAGIS--DHVRGTGFSFVRIRRPIYVNGKE---VFCALSLCTRDKlVNQRAIQQVGMLLSRSDFIDRVRAVGTYEEFAETVSQ-- +>tr|D6XZQ1|D6XZQ1_BACIE Transcriptional antiterminator, BglG OS=Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10) GN=Bsel_0902 PE=4 SV +--------VSAAKGPDRLEQIMDEGISLLEDDGLVTEGFYDDIHHTvfQKKYLYEIIPGLLFIHGNS---DHVLKAGFSLVQLKEPYVVEGKL--HSTAVLFMATPDkDAHIPQLQYLYQIFMNERKVKDLLDWTT------------ +>tr|B9Y4E8|B9Y4E8_9FIRM PRD domain protein OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_00679 PE=4 SV=1 +---FSPRYFNGSLKGSVRDEVFREVAKAFDNWKEILAM----FWEAEHILSHETTKGVVFLHTLKP----LPESFIYIGFLKKPIIWNKLW---AQAVIFVNINGDlDSLRLGYDFISEMINDPREPFSGKITEYEDLIEVLSKN- +>tr|H1BMU6|H1BMU6_9FIRM Uncharacterized protein OS=Eubacterium sp. 3_1_31 GN=HMPREF0984_01703 PE=4 SV=1 +---LLPSLYQEGLLCKNKQDVYKELEKLLAaMWGEAEATK---LVNGIYHLGNEVGNDIICLHSRYD----YHTPFIAFLSLKNHMLWEKQH---VRYIFFMNMNAEsDKemVHHMYHLISNWAdVKTRITYYAKNQDYQELIESLDNS- +>tr|N9VDC9|N9VDC9_CLOIN Uncharacterized protein OS=[Clostridium] innocuum 2959 GN=HMPREF1094_00865 PE=4 SV=1 +---IRKEYFFTNLECNTQEDVLISLANLLAsEMGQGISNS---IMNGICLSFSEVGNGCVILHTLYD----LAIPCVAIMLLKAPVLWNHSY---ISTVVFCNVSVLEYslIEQIYQKISQWCeKDHRYI-----KNYEQLIKSFE--- +>tr|A0A1T5MMD7|A0A1T5MMD7_9CLOT Transcriptional antiterminator OS=Maledivibacter halophilus GN=SAMN02194393_05030 PE=4 SV=1 +---FCKDYLITGIKGNSRKEILKQIYTKLIeL--KVAKRK---ELSKMPFVSHEIGNRVVNLQDLYK----VCHkEVCLIVVLEKPILWEKSI---VEVFFLIKTKKDgDKdlF-ILCDLFSKFAsDKEKIKDLIDKKDYESFMKDILEY- +>tr|A0A0F4M0J2|A0A0F4M0J2_9LACO PTS IIA domain transcriptional regulator OS=Lactobacillus mellifer GN=JG30_00460 PE=4 SV=1 +LRLLHPENTIFTSQFLNWETAYLMIGKLLQKHAYIKHSYWTAAINNIVSYGPYivLRDNLAIAHAQNN--HSVLADTIGLVYAQKGIGFDSKN--KVQFLLFVALQsDDDYLAVINAILNVYDNYNFFETIQD--------------- +>tr|A0A0L8ATL5|A0A0L8ATL5_9BURK PTS mannose transporter subunit IIC OS=Limnohabitans planktonicus II-D5 GN=H663_19215 PE=3 SV=1 +------------------------------------------MGASRGQLVIMAPLsGVLVSLDSVP--DPVFAQ----KLVGDGVSIDPTSD-------VLLAPVAGTITQLHKS------------------------------ +>tr|A0A235IIU5|A0A235IIU5_9NOSO Phosphoenolpyruvate--protein phosphotransferase OS=Nostoc sp. 'Peltigera membranacea cyanobiont' 210A GN=ptsP PE=4 SV=1 +------------------------------------------LGVRELAAQMVQGQvPIAVAAGIEDPE------------NPLG---TDPIQVYE--AIASVFSDDGVLVLMDLG------------------------------ +>tr|A0A1F6GF09|A0A1F6GF09_9PROT Uncharacterized protein OS=Candidatus Lambdaproteobacteria bacterium RIFOXYD2_FULL_50_16 GN=A2527_03755 PE=4 SV=1 +-------------------------------------KLLAALDQREAEFSSLIGYQISLPHVYC---KETREPLMIVAKAMGHLASPVGG-EPISTIFMIISPKDQpevHLEQISKVAKFISKEKNRFALAAAKDEAELFYALERG- +>tr|A0A183V6W6|A0A183V6W6_TOXCA Uncharacterized protein OS=Toxocara canis PE=4 SV=1 +---LNKSVLLLDLQETSLEEIFAKIIH---EMDIQEPEFtseqvrsvlftqdagnqfhiLSRTVQSICTTGtiggsfd---ydQTWICALCMLN----TVQHRHVAIARLSHPTNLGRTM-QDLRFIIIVIAPsratwTL------------GSDSSWRKPLSSS---GELPSLFIN-- +>tr|A0A1V9XTB9|A0A1V9XTB9_9ACAR Anion exchange protein-like (Fragment) OS=Tropilaelaps mercedesae GN=BIW11_07582 PE=4 SV=1 +---L---SIILDSQEMELVAIVK---QLLGKMFNENTALitatleniffce---TDNAISDLLmsasaqqsKGIvfdSSYLCIPCSMP----TdFAKRFVGVCRLATAVNFGTSA-DRVRFIVVVVTPvnvkaTKTSLEVMRTFSTLLSNPWIRHRLTTEArTENDLKAILTD-- +>tr|F6IXS1|F6IXS1_LACPE Transcription regulator OS=Lactobacillus pentosus MP-10 GN=LPE_02508 PE=4 SV=1 +---LQANHFYHVSGKHqNVSQVLKAGLVNFSDRGLLTSEQSVSLVAREEAGNQLVLNHVSLPHASA---KLSETYKIFAITFDGVLEIDNT---PIYVILIVLANEkqTDSGQIFGYLYTKLKQLND-TQLQNIDDYQTLIKYLG--- +>tr|A0A0R2N289|A0A0R2N289_9LACO Frv operon regulatory protein OS=Lactobacillus saniviri JCM 17471 = DSM 24301 GN=IV56_GL000437 PE=4 SV=1 +---LPPNHFVSLPLIKRFDVALKKGLDIFVERQLLTAEDEKAIIDREAAGNQLILNHVSLPHTTS---THFAEYGIFAIKLANEVTVADT---TVQLLVVVLANTsqVERNTIFSYFYQTLRKQPL-KSINAAHEYEDVLSLLG--- +>tr|A0A1A8XE12|A0A1A8XE12_9PROT Multiphosphoryl transfer protein OS=Candidatus Accumulibacter sp. S1 GN=fruB(HI PE=4 SV=1 +MMPTVATRLEIVAPlsgvlVPLESVPDPVFAQKM------------------------VGDGVSLDPTTGDLLAPVAGTVTQLHKAhhALTITTGQ--GIEVLLHIGID------------------------------------------- +>tr|H7F4P9|H7F4P9_9LIST Transcriptional antiterminator, BglG OS=Listeria fleischmannii subsp. coloradonensis GN=KKC_06027 PE=4 SV=1 +----------GSDMTRNKEDNLRSFSQSIANKkpDLSSDKIFKKLSSLEARQKIISgGTNSAYFLVN-D---NVQTASTHIFTLNHSIDFQIEDGLKspVSTVMVFMLPyklNAELLEITTYLLTVLTEDDAAILLAESGDETKIISLFTTY- +>tr|A0A0R2I9X9|A0A0R2I9X9_CARML Uncharacterized protein OS=Carnobacterium maltaromaticum DSM 20342 GN=IV70_GL000323 PE=4 SV=1 +----------IQQVVKNIEEVSEVITKVIYQNqpKSRMDYLINALTVEEQQGGVGIpGTTLALFFIRNE---MISRPLFQIFTLRNHVRLQATDKTEieISTVLVLLAPeklATGSIDILSRLSTLMIESDEVIQSFESGDRNKITSLVIQK- +>tr|A0A1E5G819|A0A1E5G819_9ENTE Transcriptional regulator OS=Enterococcus plantarum GN=BCR22_07635 PE=4 SV=1 +----------LNENLGTMEDAVRVICTQLLEKapEIDVEALVSTFLYDGNWKAFGLpGTKIGLFHARNE---SIKEPVFQLFSLEQSLSIETMNHTKmpIDRIVLLVVPekfSQEGLEVISYISTLFVDDQDMIQQVEDGVKEEVTTYIAQK- +>tr|A0A1S7FSL8|A0A1S7FSL8_9LIST Transcriptional regulator OS=Listeria weihenstephanensis GN=UE46_04490 PE=4 SV=1 +----------MEETQHNLEDTLRAVCMAMFEQerDIQVEILLKSLLEREKWSGFGIpETKLALFHVRNE---FVHQPVFQIFSLQDAVDVPAMGGGNvaATTLLVLLAPeklAPQGLEVMSFISAMAIENEGTTRLLESGNGAEITTFVIGK- +>tr|B3S4Z9|B3S4Z9_TRIAD Putative uncharacterized protein OS=Trichoplax adhaerens GN=TRIADDRAFT_59409 PE=4 SV=1 +---LTESTILLDIAQTDLESIVEKMLTKLFDKEQLQCSMSEAVISllskdievckfRNLMQGTEYseGGGIAITQQYLVafcQLQTLTGRHVAIGRLKEPTNLGPTS-QEVNFIILILTStkekgTKNAVEVARTFATVFADEEFRQILMDATNDEEFKKFLNE-- +>tr|A0A087CGX0|A0A087CGX0_9BIFI PTS system, IIA component OS=Bifidobacterium psychraerophilum GN=BPSY_1370 PE=4 SV=1 +-----------NWQVHDKAALLSRVSQYLLDERMIVdsDAITWALTTREDLGNDLVAPNVAIPHAQH---AAVEHAVMLMVKLRHPLlDWCPGA-DVDRYVFSLIPttPSARDAGELKEFYTDIADDQVMDRL-SLGDQREIRTIFASRR +>tr|A0A0E2XEV7|A0A0E2XEV7_OENOE Uncharacterized protein OS=Oenococcus oeni GN=EL27_04075 PE=4 SV=1 +-LLVGNNVIFINNHTSDFFSVLISGLKKLIADKAISKNEGQMILEREREGNQLLINGVSIPHVTIPN-TSDNYRILAIVPKEKPILNNENV--YLLLIVLVGQMQIDKSSIFSYLFHLLKNKNY-QSIIDLRNRKDVIKLLTD-- +>tr|U3JVM2|U3JVM2_FICAL Uncharacterized protein OS=Ficedula albicollis GN=SLC4A11 PE=4 SV=1 +---LARASIILDETATSLDDVLREMLKHFAEDPEnmepscnfekiMSTLFTDSGTPREGngthdvsestgmnvqtgpshlkfhllsdtiqgvtATVTGVQYQQSWLCIICT-IKSLQRRHVCISRLERPQNWGENS-CEVRFVILVLAPpkmksTKTATEVGRTFATMFSDITFRQKLLETKTEEEFKEALVHQR +>tr|A0A0P6IPS9|A0A0P6IPS9_9CRUS Sodium bicarbonate transporter protein 11 OS=Daphnia magna PE=4 SV=1 +---LEQCVLLLDDEAAQTSTPV-DLVDLLLGKMDlpvavveeaKTILVTHDIV----pslaktiqatyStrdNVNIFDYDESWLCTMGD-IPSLAQRRIAIMRLKHPTNMGETC-HDVQLFVLILCPgkekgTKNGLETSRTFATLLADVNLRRQLLEVTNEEEFKELVLKRA +>tr|A0A183BP25|A0A183BP25_GLOPA Uncharacterized protein OS=Globodera pallida PE=4 SV=1 +---LDRCAILLHVTETLLEDVVLKMVEEKPEYHGpgegvaiendrlefvsfrqiCDKLFVSIDT----rtsltstefalrvhlqgvlTdEQLGVVEDQRWLVLYCS-IDRLSRPRVSFARLAKPTNFGNAN-L------------------------------------------------WPKS +>tr|R7Q0Y4|R7Q0Y4_CHOCR Putative sodium bicarbonate cotransporter OS=Chondrus crispus GN=CHC_T00008463001 PE=4 SV=1 +---AQTAPLLLNLPPAPPRRILRLLLNHLVDAGQipataineaVHALFGEPNSSAPNnscaqnsedafdtlhqrppglpLdadnnsrdpqtsrdtnfrhpadqLPGHWHKnvlGSGFIipfARLNA-LNTCDRCVVAIARLTSSCNLGVANGSLVRFVVLVLGPvkelkeTKTPFEIARTLSAMFQDDQFYSDARLASSDGHFRDAIRKYL +>tr|A0A0R2GUD8|A0A0R2GUD8_9LACO Uncharacterized protein OS=Lactobacillus acetotolerans DSM 20749 = JCM 3825 GN=FC77_GL000643 PE=4 SV=1 +----------LKHNSSRIEDVIKQCLDNCDSDIVKDkKIVADKLFKRIKLTPVGIPGsNLALFHTSS---KGISRCSFTIFDLENDLTLQAMDHIDiqVKRILLMLGPamlSTAEQKVMSLVSSMIITNDDNLHLFSVGQQEQIKNAIAVQ- +>tr|A0A0R1ME33|A0A0R1ME33_9LACO Transcription regulator OS=Lactobacillus capillatus DSM 19910 GN=FC81_GL000811 PE=4 SV=1 +----------LNNNNEKLAELLVQVLAKVPTAVVKEpQQVVHEMLKRVKAAPVGIPNaSISLVHATD---KSVLKPFFSVYELRAPLTMKAMDQTPiqVKRILLMIGPapmTDFQNNLMGTISGAIVMNNRYTAIFEKGNVDKIKNLIAAQ- +>tr|A0A0L7Y262|A0A0L7Y262_LACPN Mannitol operon activator BglG family OS=Lactobacillus plantarum GN=AVR82_02345 PE=4 SV=1 +----------IRNDDETVAEMLVKITRHIDSNLIHDpLEVAGRLLHRLGLAPVGIPNtNLALVHTLS---QEVTAPYCAIFELDQPLPFKSMDNQSirLQRIVLMLGPaniSDFENRLMGKLSALVIESQANTQTFMTGDRQQLYQLISKA- +>tr|A0A222W5Y7|A0A222W5Y7_9LACO Uncharacterized protein OS=Lactobacillus agilis GN=BEN83_09315 PE=4 SV=1 +----------VANQGSDLGASIEETLAHIPGEIINDkEKVTLALLRRINLAPIGIPDtNLALLHTSD---AGVNQCYFGIYELAHPIKMLGMDREEmqVSRYTLMVAPkevTDLEQKVLGIISSSIVMNSENTNVFETGTSEAVQELLANQ- +>tr|A0A139TKJ4|A0A139TKJ4_9FIRM PRD domain protein OS=Candidatus Stoquefichus sp. KLE1796 GN=HMPREF3037_00318 PE=4 SV=1 +-DFIKPKNILLNSSMESKTEVLQYISKVFQL-------SFSELDLKENVGNMAMEGHIAIPQMIG----YSDIVEEMLITFNKPIIWDH---EFIQCVLFVSLPKRfflRYQGYYSLLQKLVMDQEAIEKILSFQKTKEVEEFLSRYH +>tr|G9R068|G9R068_9FIRM Uncharacterized protein OS=Coprobacillus sp. 3_3_56FAA GN=HMPREF1021_01312 PE=4 SV=1 +-DFLKKEDTYFI-DCETKDDVISYIFEHESV-------SFETFYHTNPLIGFETSLQTVIHYMPI----YNQKSSINAYLLSKPIVWKN---KLVKIIFVLKLGID-SEQLLQSLQEFFFQKECMDTFLNNM--------ILEEG +>tr|A0A1C1ZYI2|A0A1C1ZYI2_LACRE Uncharacterized protein OS=Lactobacillus reuteri GN=BBP13_12895 PE=4 SV=1 +-SIFDNLRIYRESSQIDHERIIAGMVAAAEREALVSnkEAIVQTLKEREEQGGLGIpETSMALFHCRHE---GVGKLLFQISHLHYPCQVKGMDGKMmeVRNLLLMLAPENltiREQEILSLISTNLIEDKEAMMIFSSSNEEMIRKNLED-- +>tr|A0A099YCT2|A0A099YCT2_9LACO Uncharacterized protein OS=Lactobacillus mucosae GN=LX03_02675 PE=4 SV=1 +----------------NRDEWLKHVAGIIPDFVDDSTPLIHALSNREEIGSTRLAEKLVMPHVVMP---GIADSYLIVSQLESPVEWFDNHSVDTGTFLIV----EGNDEAISNFVVHMADDSFVERLCERGIEKKTIESLLKE- +>tr|A0A0R1V5S9|A0A0R1V5S9_9LACO Uncharacterized protein OS=Lactobacillus gastricus DSM 16045 GN=FC60_GL000937 PE=4 SV=1 +-------------QVKDYQDWLYQLGHLMTKEPDLQNELIQQLVGREQVGSTIIDPGIIMPHIINE---NLFDHVVIVSHLQTPLKLADQN-VTTAVILLM----RTIDTQIDSFMKALISDDHLQQLKE--------------- +>tr|A0A1M6NUR2|A0A1M6NUR2_9FIRM Mannitol operon transcriptional antiterminator OS=Anaerocolumna jejuensis DSM 15929 GN=SAMN02745136_01459 PE=4 SV=1 +LQIIDNFLFIEQVAAENEEMLSHFVSRSLAVSGADRFQMEKNMENKEQKGSAILsRKRMVLYHLRS---EAVREPGMAVLRLKSSIGSIGKDGniQKADTFIFLSMPvdtEGCVLELINEITRKIISSDFSLTLKQSGREEIIIEL----- +>tr|A0A1T4KXV1|A0A1T4KXV1_9FIRM Mannitol operon transcriptional antiterminator OS=Garciella nitratireducens DSM 15102 GN=SAMN02745973_00716 PE=4 SV=1 +LQILNNFFLMEYEKFENIYQLIDTLSYKISEKEENAIQIKHDLIEREKYGGTILtGFHAILLHCRT---SGVKQLFFGLIRIKKSLICSNREEke-PIELAIIMLIPennNQFQREIMSFISSKIIEeAGLLQDLKQAQQEKVYTRL----- +>tr|A0A0H3YIY0|A0A0H3YIY0_SCHMD Slc4a-9 (Fragment) OS=Schmidtea mediterranea GN=slc4a-9 PE=2 SV=1 +--FLKEATIILDMEEFQPIKIVEKILYKIISDKEIEigQSHVKEMIAEAKealftqveisnysyqrltrtikgillnpVDGTTFNQPWICAMCSF---SSITKRFISITRLKYPVNFGRNG-IRVNFVILVLTPKkekesKSDFELSRTFATLFSSIEYRNEFMNTDSPDVFRQYLKSE- +>tr|A0A1S9C1Q1|A0A1S9C1Q1_9FIRM Uncharacterized protein OS=Epulopiscium sp. AS2M-Bin002 GN=ATN32_03235 PE=4 SV=1 +-NLINNIFFYKSNDITSKLEIIQKISILLGETEADILAIQKGLQERELISSTYIrESNVYLFHCKT---SGVTHSKFGFFKLTNP--FQNKSGYWVCGGILLLIPEnstKFQIDIFTMISKSLTDERIMEKLITVESKVEVVSVIESS- +>tr|A0A1C5TZU9|A0A1C5TZU9_9FIRM Probable licABCH operon regulator OS=uncultured Eubacterium sp. GN=licR_3 PE=4 SV=1 +--LLDHIRIGRAPVLQERQEILAYAASLFSDTPEMESHFYEIMKKRDQIADTYMkPFHALLLHGKS---PDIMHPCFGYVHLEPPIYENAR---IILGAIVTFIPEndpdQVSAPIVSEIIGALMEQPELLKALREDDDERFTLLLE--- +>tr|A0A1Q6MYZ8|A0A1Q6MYZ8_9FIRM PRD domain protein (Fragment) OS=Clostridiales bacterium Nov_37_41 GN=BHV95_06040 PE=4 SV=1 +--VLDNIKISTGENIKNKKQLIEYAGELFARNETTATEITFALNKRENIASTFIpSMNALFLHCET---KGIRHCRFGFVYLNDEIIEDGK---PIKGAILMLVPQgdgsKVYREVMSEISGALAEKDQIITYLFDK------------- +>tr|A0A1Q6L9Z6|A0A1Q6L9Z6_9FIRM Uncharacterized protein OS=Clostridiales bacterium 36_14 GN=BHV87_05315 PE=4 SV=1 +-DLLDNASWIESSNCSDFFDALKLLYNELTKELPLDVSFLASIMQRESILTFAHHPHVSFVYQIG----DYEKTSACAMTLDHRIKYHDN---KIRIIVLVAIAKNDSNFIFKMLNELFNSDFNLNDLKFLKTKKEILNALKTY- +>tr|A0A160PSR3|A0A160PSR3_CORGT Uncharacterized protein OS=Corynebacterium glutamicum GN=N24_3085 PE=4 SV=1 +-----------------KDKSLKELVDAAVRFDPTStEDILEKIQHRDQIGSTEVAPGFFIPHVVT---DSVPRIQLVLGTEGE-----------VTWLLVLMPSNavPESKRALSLLMRQLAYEEEVSRIRSFSSTEQFQHYLAVIE +>tr|A0A1T4N5D5|A0A1T4N5D5_9ENTE Lichenan operon transcriptional antiterminator OS=Pilibacter termitis GN=SAMN02745116_01312 PE=4 SV=1 +-------------EGISYEENLERCIECLSNQGILDEQFYERLSEREKLRTTVEP-PFAFPHTIN---SKSEQLVLIFGKSSEGLESHFG---KVHFFLLLCIPeemdeekERVLLQVYEVVFRLFRRYILQNGKKQLPTIDELKDLVEAS- +>tr|A0A0R2BSI9|A0A0R2BSI9_9LACO Uncharacterized protein OS=Lactobacillus coleohominis DSM 14060 GN=FC35_GL001757 PE=4 SV=1 +------------VDVKNYSGWRKLVIKKLMLSDKLSADLLVQLQERDRLGSIQVDEHVIMPHVVS---NKLPKSWLIISQVDRPIKYGTSNDITTGIYIFSRPKDSS----ISSSVDCLADESVMKALQNPKlSYQQLMELLR--- +>tr|A0A1V6EQF1|A0A1V6EQF1_9BACT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Candidatus Hydrogenedentes bacterium ADurb.Bin101 GN=B +------------DQAQPLDMALQTMAARLCDRDAPRNDILELLRQAAANYPVELVPGIVMLHAHS---DSVGSTTILVGAGGAGWSFPGVE-TPAGTILALISPrsksPEIHLAALSQLARACREGEFTRAIREPMSAEDIAGVLK--- +>tr|A0A086BPF9|A0A086BPF9_9BIFI Putative phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Bifidobacterium bombi DSM 19703 GN=BBOMB_1226 +----------FLKDCTDLDRALHVLSEYVCRAGLGKeaSRIENDLGSRCRAGDVMLSHGLVNPHAQS---SNVLVSTMIYVKFAKPLRANAVyastvESGFSRMLLTMLSTSptQEEVREVCGWYRSMADDEILALLAN-GTQQEIRRLLLEEG +>tr|A0A1C4AA63|A0A1C4AA63_9BIFI Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Bifidobacterium bohemicum GN=GA0061078_0836 PE=4 SV=1 +----------SGIDIVDKAGLLMWVASYADRRGVTAdgRRLARVLEDRENAGDTRLAIGLANPHAQD---RVVNSATLLFVKLLRPLADWRPGDCIDRFLFTLLPERvaFNEAARIKAFYRLIANETAMNVLRV-GDQEEIQSILPTER +>tr|A0A1D4SJJ3|A0A1D4SJJ3_STAAU PTS system mannitol (Cryptic)-specific transporter subunit IIA OS=Staphylococcus aureus GN=SAMEA1708664_00507 PE=4 SV=1 +-----------------------YIADYLYQCDAINdpTSFAELLEQRLIDNPGWIlsPYPVAIPHLRD---NMIKHPMVLITVLEEPLILPSiqNDNQTIKYMISMFIPDNDFMASLvSDLSEFLSLKlESIDTFME--NPQELETLLRNK- +>tr|U2QJ27|U2QJ27_9BACL HTH domain protein OS=Gemella bergeriae ATCC 700627 GN=HMPREF1983_01334 PE=4 SV=1 +----NVYVSELFTADTDIKNMLVDIFKKVNLKSGNQQNIIENLIGRHEKSSVVIpKTKLALFHTLE---NSLTEPFVIICNLKNEIELINVSLNKemVRTFFIMVSPNeERYTNFLGQISIAILNDEVLIKAINSKNRE---------- +>tr|A0A1M6VIK5|A0A1M6VIK5_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=[Clostridium] lactatifermentans DSM 14214 GN=SAMN02745138_02381 PE=4 SV=1 +--LLDHVQLLVLPYAQDKQELLYVASGMFTETKEARELIADSLAKREQISSTYIrDFQMMLLHCKT---GGVKHCCFGYIRLKRPLFQSEG---VIEGAIVMLVPkegDSLEAGLMSEISSGLLEDEAFFSAVQKKGRISIIESLEKR- +>tr|A0A200IXP4|A0A200IXP4_ENTFC Transcriptional antiterminator bglG OS=Enterococcus faecium GN=A5806_002131 PE=4 SV=1 +--LLGRFFIQELDNPETISETIRSLFPYFPEGLVTDeEVVHRRLLKRYEQAPIGIpHTNMGLFHASS---SLISKPIFCIFNLKHPLTIEGMDRQPVdlsRMLVMLAPSPiqEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLA--- +>tr|A0A116RD67|A0A116RD67_STRSU Mannitol operon transcriptional antiterminator OS=Streptococcus suis GN=mtlR PE=4 SV=1 +------------GQQTSFDEAVVATVGELEH--VADrAYLADKLLTRFSVSPLAIpQTNLALIHTQS---SQVRHSQFVIVELENSVSALSMNNQQeaVQRILVMLTPlgvEAEVRELMTAISQSIIENKLYTEIYRTGNQEIIYQLLNS-- +>tr|V6Z174|V6Z174_STRAG Phosphotransferase OS=Streptococcus agalactiae LMG 14747 GN=SAG0136_05145 PE=4 SV=1 +------------DNAKHFDQSVATIVAQLPG--ISDtNYLTQKLIQRFHQSPMAIpDTGLMLLHTQS---HTVETSGFYICDLTKTISAVSMNQQTenVSRVLIMLTKtseNDSVRDLMTAIGQSIIENHLYTEIYKTGNKAIIYQLLNQ-- +>tr|S7TXT7|S7TXT7_DESML ATPase, P-type (Transporting), HAD superfamily, subfamily IC OS=Desulfococcus multivorans DSM 2059 GN=dsmv_1861 PE=4 SV=1 +---LQPDHVHLDVRG-ALEPVLRRMAGGLPH----GEELLERLQPLLEDMDTLLlmpSDDVVLPHFRM---AGLEEPQLALGISRRGIACRGK---SPRIILFLVSPeedPSGHLKLLQRVSALLPELAKR--LAAVRSPSQAIRILAEGE +>tr|A0A0T6A6K4|A0A0T6A6K4_9BACT ATPase P OS=candidate division NC10 bacterium CSP1-5 GN=XU15_C0003G0049 PE=4 SV=1 +---LEADLILLDAEQGsgeFLHPlaERIVAAREVPQ----RDDFLAEV-------SkDLVenrIEDVSLGHALL---DEFDRMAI-------AIAISGtS---FQAITILVLSPlkeSGTHFQVVSKLEGMLQERAFREALRSACTPEAVIQVFER-E diff --git a/esm/source/examples/data/hhblits_uniclust_2017_10_1xcr_1_A.a3m b/esm/source/examples/data/hhblits_uniclust_2017_10_1xcr_1_A.a3m new file mode 100644 index 0000000000000000000000000000000000000000..db80f9f364b8ee17ce00f57f276f79bb6aebf598 --- /dev/null +++ b/esm/source/examples/data/hhblits_uniclust_2017_10_1xcr_1_A.a3m @@ -0,0 +1,502 @@ +>1xcr_1_A +CAEFSFHVPSLEELAGVMQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNQKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPVIQTESEHKPPVNGSYFAHVNPADGGCLLEKYSEKCHDFQCALLANLFASEGQPGKVIEVKAKRRTGPLNFVTCMRETLEKHYGNKPIGMGGTFIIQKGKVKSHIMPAEFSSCPLNSDEEVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHFFSRHGEGGHYHYDTTPDIVEYLGYFLPAEFLYRIDQPKETHSIGRD +>tr|T1J6L6|T1J6L6_STRMM Uncharacterized protein OS=Strigamia maritima PE=4 SV=1 +--KLELYQPEANELRSVLEKGLKNSFEEASVQIIDCPNLKKEPFNLAAKGICGRPTLIDVGGVRNLQPVPLRNKIYNLDKLTQIAHNPEAFLMGAGGGPFHITSVNCEVSILTRWDphKNSS--FLQCFLvfrtlSRVrilssltsvlisrchkdrpqmpdpgysalgprtawleilhiiaglkfmanirtsatghgrnlsyiarlDP-VNEYKLl--QMPE--NRECGLMLNALVCEGKEGKVMQVKAKKRTQDTNFITAMRETLKVAYGDKPIGFGGVFLLQSGNAKLHIMP-DFPIYPLNDDATVNSWLKFYDMHAPLACLSTFVTNDPlNMDLRIEHTHCYSDHGQGGHYHHDTTPDTAEYLGYFVLCNTLYRIDKPAMLHRRK-- +>tr|A0A0P5YSQ6|A0A0P5YSQ6_9CRUS Ester hydrolase OS=Daphnia magna PE=4 SV=1 +--NCQLHVPPLSELADVLRQGLESHFAHVQVEVVDCPDLSSSPFHLAAPGLGGEPCLVDLGGVPYLVPTVQRDRTYDLADLPGLMNVKDgtILMIGAGAGPWQHLNTNCEMMTNLSLTleEGKSNIVNGTRLATVdpagqrmlhvvxxxxxxxxxxxxxnivngtrlatvDP-AGQRMLHVVPPE--QTRCSLLNNLLISRGQPStPVLRIRCQKRTGPNNFVTCMRNTVAQHYGDKPVGIGGVFMLDNGQARLHIMP-DFSPCPLQTDADVNNWLHFYNATGPLINLSVFISHDPGLDLRVEHTHCFSVHGEGGHYHEDVSPETVVYEGYFTPAERLFRIDRPSETHRVGRD +>tr|A0A177FAU3|A0A177FAU3_9EURO Uncharacterized protein OS=Fonsecaea monophora GN=AYO21_04498 PE=4 SV=1 +--KVELAPPSLSALAQGIVSGLCSNFSISDCSVANPPDLTAAPYHLAGPGLSGSPRIVDVGGPPNLSPTPNMTKKYDLTAIAGQVGmSPa-tGFMLGAGAGPFYVLGQNSELMPNFAYGtaAG-ggeDVVRNRTHY---akiT-PSD----tVCCAQIPqASTGFAFMCNLFCSDGVPGQCLHVTARSRTGPLNFTESIQHGLQATFGDk-LISLGGVFLIKKGKARLHVMP-DFPTQPFNSRADVERWLRYFDMsfdagggadtgakdkhaegggsggggdgdgDGPLVCLSVLHSGDDaGLGLRMEHTHCFTvpsspssadadanlnkdrETTKGGHYHYDLdeTMDEIEYEGWFNVAETLYRVDQPGGSTA---- +>tr|B4LCD4|B4LCD4_DROVI Uncharacterized protein OS=Drosophila virilis GN=Dvir\GJ12897 PE=4 SV=1 +--EKPLHVPTLEELQQVIQGALRKNFATASVQVGDCPDLKAPQYGLVESGLGGRATLLEVGGPPHLLPLVQRDKLYNIKEIARRIQgA-GkIFAVGAGAGPYPIRSSNCEGIYNLSVSaSD--ELTNGSYT---atvRGEQEECVLe-RIPST--EARCALLLNLYLSRGEAGPVLKISAKQRKGELNFIECIRKGLEEHYGDRVVGLGGIFVIKKGAAHQHVMR-DFSKTPIHTDAEVNEWLKFYDMPAQLNALGTLVTKEHDLDLRLQHFHSFSFSNWGGHYHYDTTPDTVEYEAYLNVAERVVRVDKPLATHKVGRD +>tr|A0A183SZ16|A0A183SZ16_SCHSO Uncharacterized protein OS=Schistocephalus solidus PE=4 SV=1 +--VLRTFEASLEDIAAAFETGLKSCFQNVSVSVADCPDLTNKPFALPSSGLLGNNTVCDVGSFSYLIPVADTSRRYTFSEVISASKlQT-GQLIGAGAGPFFTAGKNCEammgnrdpnelfntstnyidwsyyylkgsrqlashelkstrdfqmftlMAAIVKVAenD---VRSNNTLH---gvyNKSED------KPGVLkaTDNNFALLGHFLATEGNPGKVLAVDVSVRAKDGSIYTFLREALTAKFGNesAPVALGGAFVLDNSKGRFHVMP-DFPKKPVDSPAKISSWLKFYEMSPPVMGVGTIVSHDPvGYFLSTlEFVDCLLdrfn---NSSS-YGE--P---EFQTVLIVTPFFMRGNN---------- +>tr|A0A158R7K1|A0A158R7K1_TAEAS Uncharacterized protein OS=Taenia asiatica PE=4 SV=1 +--NHSVHEVQKEELVEVLREGLKDCFQSVKVNVVPCPDLTALPFGLLRPGLAGQSVACDVGSMAYLLPVADTSKRYSFDQVVDLSKvSG-GHLFGAGGGPFFTHGKSCEMAASLEFAngK---ICSNSTLH---gvyDEQTG------APQVIkaTDNNFGLVGQLLSTEGLPGSVIEVDVTGRLKEGSVYVFLREALTAAYGKldKPVVLGGVFVLTDSKARFHVlvsvnwvphvtisssmisylelftvdenlkapsliinqQP-NFPPYPVDTPARMAEFIKAFEMDPPVLGMGTLVSHDPyGIDLKLEHFHCYNeakn---LAGHFYWD-tEPEKAHYRLYLTVAKSLLRIDPKKKA------ +>tr|M3B464|M3B464_PSEFD Uncharacterized protein OS=Pseudocercospora fijiensis (strain CIRAD86) GN=MYCFIDRAFT_214637 PE=4 SV=1 +--KHPIAPPSLEELVDVLTPALRANFEKAKVSVERCPDLRHPPYYLAAPGLSGDECVADIGGQPNLFPEPRLECKYSLIEIAKEMQmDP-dgGHLLGAGAGPFHRIGLNSELAPNLSWSnnFEN--VVNQTYY---tkfDDSN-----grhAAVCERSPTTDCALMMNLYGSSGLPGDVIKISARARTGHhKSFTECIRKTLAEKYGDdRPISMGGIFLIKAGKAHFHVMP-DFPPKKqmpFKNAKQLn-DWLTYHDFEAPIVCLTVFHSADPgkKLGLRMEHTHCFSidga--NRGGHYHYDLpagdGVd-EVEYEAYFNTAKTIYRIDTPEVTLERDLH +>tr|A0A068Y3Y1|A0A068Y3Y1_ECHMU Ester hydrolase C11orf54 OS=Echinococcus multilocularis GN=EmuJ_000699900 PE=4 SV=1 +--NHNAYDVQEDELAEVLREGLKDCFRSVKVNVVPCPDLTASPFGLLRPGLAGKSVVCDVGSMTYLLPVADTSKRYSFCQVIESSGvCG-GQLLGAGGGPFFTHGKSCEMAASLQFAngK---IASNSTLH---gvyDEQTR------TPQVInaTDNNFGLVGQLLSTEGLPGSVVEVDVAGRLKEGSVYVFLREALTAAYEKldKPVALGGVFVLTDSKARFHVlQP-NFPPYPVDTPARRAEFIKIFEMDPPVLGMGTLVSHDPyGIDLKLEHFHCYNeakt---LAGHFYWD-tDPEKAHYRLYLTAAKSLLRIDPKKKA------ +>tr|F0XT09|F0XT09_GROCL Mgc81809 protein OS=Grosmannia clavigera (strain kw1407 / UAMH 11150) GN=CMQ_5752 PE=4 SV=1 +--RHALSPPLLHEVAAVLATALPRNYRCSSATVVECPDLRTAPFGLAAAGLSGRPTVADVGGQGNLFPTPRRDKNYGLVDVAARMQlDE-qrGALLGAGAGPNRVHGINSELAASLSWQggQEAk-NITDCSRS---iriAA-------dnhghdHVQCVLSGSTECALMANLYGSLGLPGPVLRVTARGRHGNaASFPEFLRATLHDAYGPdRQVSLGGVFLFKTGRARFHVMP-DFPPASalpFADRQAVe-RWLTFHDFAAPIVCLSVFHSADPhQLGLRIEHTHGFAadr--PAGGHYHYDHlardgHDdDEVEYEAYFNVADALVQIDPARANYEGRGE +>tr|A0A0D1ZUB3|A0A0D1ZUB3_9EURO Uncharacterized protein OS=Exophiala mesophila GN=PV10_01807 PE=4 SV=1 +--HRALSPPSLSSLAASISSGLSTNFAHWSCDVETPPDLTLPPYHLAAPGLSGSTRVADVGGPPYLESKLDLTRKYDLAAIAQDVNlPAs-gGFLLGAGAGPFFHLGHNSELMPNYAYGtaADPcsstssPAIRNRTHY---akiT-PSN----dPVCCPLPSSTGFGLMCNLYCSQGLPGPALHIKAKARTGPLNFTQSIQDGLKATFGEn-LISLGGVFILKSAKAKMHVMP-DFPKNPFQSRKELVEWLRFFDMefggsndpTGPLICLSVLHSGDDgGFDLRHEHTHCFTvdsggdldrETSKGGHYHFDLdeTKDQVEYEGWFNVAEDLYRVDQPGQ------- +>tr|A0A151JWH1|A0A151JWH1_9HYME Ester hydrolase C11orf54 like protein OS=Trachymyrmex septentrionalis GN=ALC56_06926 PE=4 SV=1 +--PIDLYVPDKTELAIVLQNELSTDFEEVKVEWVDCPDLTQEPFNLAAPGLCGDTALLDIGGIWNLFPFPIKDKIIYFQSILEKLDrTQs-dNLIIGGGLRTERPTNLLGELIMNVLISpaANEtmT-VKNKSRF---aliklIQNRKH---f--SLKFVtdPNPYCNIYGNFFISKGLREQVLKIHVKHRTGRDF-IVSLQHAIKRfSKCSq-LMGFGGTFIIKNGKTIQHIiRN-Y-WEVPIRKKKDIHNCIKYlKIQNSPIVAFATFVSSDRHKvmslkkfqDVYLNQWhv---Hansn---DSGGYYHETvPNnTNTEYLGYFSPATKLYRINPVSEFDEMRNF +>tr|A0A0N1H4U3|A0A0N1H4U3_9EURO Ester hydrolase-like protein OS=Phialophora attae GN=AB675_7754 PE=4 SV=1 +--KLELSSTTLADLASVISSGLRNSFSRSSCTVTITADLRLPPYHLAAPGLSGSPRVVDIGSPPSPPTQPHQKIRPP---LHRQTDrPPa-ipRAAHRRRRGPFHTVGKNCELAPNIAYSdG--gRKVVNRTHY---tklEPGSD----gslvPQCLQIEeESTGFALMANLYGSQGLPGEALHITATARTGShASFTDAIQDAIREHYGPdhPLISLGGVFVLKRGKANFHVMP-DFPGPKepeLDSDEAIAKWLRYFDFEAPVVALSVLHTCGEdvvkELGLRVEHSHCFSeaedgskdqGTGRGGHYHYDVdeTKDVVEYEGWFNVAEWVYRVDRPGPEV----- +>tr|T1L2K8|T1L2K8_TETUR Uncharacterized protein OS=Tetranychus urticae PE=4 SV=1 +--TYDLDQLPLDELSSTLQDHLSKFYGHVEVSVVDCPDLSKEPFNLAGSGLGGKTALADIGGVPYLMPVPYHpAPIYSFVNLGKRMGfQDa--HLMGAACVPFQITGSIAEFMPNISYSidE-TgkTLVNHGSYY---semVDDKK----YIMRP-LASDCTNTLANVFISENKPSKVIKIVASKRVDkRgESLTVAIRDILRIAYPEk-AISMGGMFLVRKGKIYIHVMP-NdFSKTPCDTEEKANEWLNFFEASAPIVGLVTLHSKDPGFNLRDEHTHCIGkg---EGGHYHHD-tTPDTIEYEAYLNIAQQIVRVDQPVVGNEMLKV +>tr|A0A0D1YEH9|A0A0D1YEH9_9EURO Uncharacterized protein OS=Exophiala sideris GN=PV11_06775 PE=4 SV=1 +--KLFLSPPPLAELATSISAGLSTNFSSSSCTIETPPDLTLAPFHLAGPGLTGSPRVVEVGDRSYLV-KRDLTRKYDLRAVARQIDmNPs-tGLMIGAGAGPFFVLGQNSELMPNFAYGtaAGSnaQSVRNRTHY---aklK-PDG----sVQCSALSPTSSFGLMGNLFCSDGEVGPCLHIRAKSRTGALNFTETIQEALKTSFGDKLISIGGVFLITSGRVNVHVMP-DFPAQPFKDRAAMTTWLRYFDMdtadGKPLVCLSVLHSGDDgGWGLRVEHTHCFTessdsQTDKGGHYHYDVddTKDTIEYHAWFNVAEYVYRIDYPAEHQRNTV- +>tr|A0A0L1JF69|A0A0L1JF69_ASPNO Uncharacterized protein OS=Aspergillus nomius NRRL 13137 GN=ANOM_001485 PE=4 SV=1 +--KLALNPPPLCELSQVIGERLSRNFGHVVANVVPCPDLRQPPFYLAGEGLCGSECIADVGGPPHLRPCPRLDKKYSLPTIMRMIEtRQ-rSFVLGAAAGPFHVVGQNSELMPNLARGhD--GEWLNETHY---akvN-EEG----qCHLAKVPdDSKDFGLMANLFASEGLPGDVIHIRAKGRTGGLNFTEAIQHALKTEYGAq-PISIGGVFLVRSGKTKLHVMT-DFSRDPCPGP--DHEWFKFYDSSAPLICLTVFHSVDSeSWDLRMEHTHCFSthg---MGGHYHYD-tTAEEVEYEAWLNTAKLLYRIDQPGQ------- +>tr|A0A0D2X135|A0A0D2X135_CAPO3 Ester hydrolase C11 OS=Capsaspora owczarzaki (strain ATCC 30864) GN=CAOG_001469 PE=4 SV=1 +--KKALHVPSLDELSAVLQHALQANFANASATpVEVCPDLTAAPYHLAAPGINGSPRLADVGGVPYLIPTANRNVLFDLQEVATKVDLPGAFFIGAGAGSWKYIGTNCELMPNVHLGaS------NNLTTTAIVA-HDKCEL--RPYD--TTQVGVLCNVLASEGVRGPVVHVKASVRTGPKDFLSCLHQAIVSRYGQQGVGLGGVFVIREGKAKIHVMP-DFSPVPLCSDAEVDQWLKFYEMQSPLVCLSTMVSGDLGLDLRLTHTHCFSNHGEGGHYHYDTTPEVVEYEGYLVPAEHIYRIGRPQPCMSPVHG +>tr|A0A167MH11|A0A167MH11_9PEZI Mgc81809 protein OS=Sporothrix insectorum RCEF 264 GN=SPI_08962 PE=4 SV=1 +--RLELSPPSLQEIAQVLAAALPRNYVASSATVVDCPDLRKPPFHLAAEGLCGGEVAADVGGHTHLVPRPRLDKNYSLPALAKLMQlSP-drGSLIGAGAGPNHVHGYNSELSPNLSWKdgFEHv--TRNLTHS---trvVGDR----AGVACGLSNSADCSLMVNLFGSEGRPGPVIKVTARGRCGNaASFTEFLQAALREAYGPdRQVSLGGIFLLKAGRAHFHVMP-HFPTptDDrppFEDQKTLd-TWLTFHDFAGPIVCLSVLHSADPqKLGIRLEHTHCFSgnk--PEGGHYHYDLgDEeSQVEYEGYFNVAHAFVRIDKPKPGAGDSQA +>tr|A0A0D2FGD0|A0A0D2FGD0_9EURO Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.8, whole genome shotgun sequence OS=Rhinocladiella ma +--KVQLDPPTLTALLPAIRAGFSSNFKNSIIEITQSPDLRQPPYYLATPGLSGHPRIADVGGQLFLAPGPDFSKKYDLLSVARQMEmSTe-cGQLIGAAAGPFYSLQINTELAPNIHWKldRDQatDVLYNETHY---tkiIASEP----gYRCSKIDhETTGFGLMGNLYGSDGLPGDLLHIVAKSRSGPLNFAATIQDALAKYFGDk-LISLGGVFVVTHGKIKVHVMP-DFPERKFERRADVGPWLRYFNLEAPLVCLSVLHSGNDrGLSLRMEHTHCFSinedgHAVSGGHYHYDLddTKDEVEYEGWFNIATVLYRIDQPPK------- +>tr|E2C2B0|E2C2B0_HARSA Ester hydrolase C11orf54-like protein OS=Harpegnathos saltator GN=EAI_16865 PE=4 SV=1 +--KKILYQPPVTELISVLTDGLTANFEKVIVKLGRCPRDPERQPNQ--YDLCGDPTILEIGGPAYLLPLAQKDKFYNIETLLRRIDyHG-sAFVIGAGAGLWPHTtdGSNCELIIHHHINtqI--GSVVNNSRY---afvDKCTGECVVa-QHLSHNeqHQATCPILANLYVCKGEPGMVIKVYAKKRTGKLDFIASMQKALGNYY-KdELVGLGGMFTMRNGKIKQHVMP-DYSNTPLTTEAQLNDWLHFYEMKTPLTAVGTFVSAETELDLRVQHFHSFAhn-NKMAGHYHIDTTPDTIEYEGYFNIASVLYRVDQPTNKLQFGKD +>tr|E4XHQ4|E4XHQ4_OIKDI Uncharacterized protein OS=Oikopleura dioica GN=GSOID_T00011035001 PE=4 SV=1 +--SKEIPPPPLEDIRVALEKALSENYKEAQVEIVDCPNLTEAPFGLAAPGLGGKTALADVGGVPYLVPGPAKwlERVYNLDHTAS----QvdIpgALVIGAGAGSKHDVGVNSELIPNIRTRggE--NKRRNLTHC---sriDPADDSKS-LLLRYEEdlNSADFTLLGNLFFSEGkSSSKVLKVTTKTRTG---TEGSIVTCMRKGLAEafsVPVGMGGTFLQAAGTVKYHVMP-EFSACPLDSDDKVNAWLRYFNFEAPFVNMATFISKDPDLDLRVEHTHGYStvnq---TGGHYHYD-vTPETIEYVGYFTPAQKIYRIDAPTETHMIGRD +>tr|A0A0G4NWG9|A0A0G4NWG9_PENCA Uncharacterized protein OS=Penicillium camemberti FM 013 GN=PCAMFM013_S002g000337 PE=4 SV=1 +--KHLRDPPPLEELAAVIEKALLSNFKTASATVAECPDLKQPPFHLAASGLSGSPRIADIGGQQHLFPRPILNAKYSLLSLAQDMEmSP-maGFLLGAGAAPFQDIGQNAELAPNLSWRssE--kapsfdepslLTFDNGTRV---ikvQ--GD----rdqTPVCDRTSSTNCALMVNLFGSDGDTGPVLKINAKARKGEe-NFTDCIRYGLQKVYGDsKPISLGGVFLLKSGKARFHIMP-DFPPEDqlpYRDRKQLeTEWLSYHIFQAPIVCLTVMHSSDPeGLGLRMEHTHCFGvngn--PKGGHYHYDIqdgd--EEVEYEAYFNVASVVYRVDRPGI------- +>tr|A0A131ZWZ3|A0A131ZWZ3_SARSC Ester hydrolase C11orf54-like protein OS=Sarcoptes scabiei GN=QR98_0016170 PE=4 SV=1 +--TIQLNEINLDELSNRLLDGLRNKFEHCSVSVVDCPDLTRPPFNLAASGLCGRTAIADVGGVPYLLPLVKRDKIYSFKQIANIVDpGQq-CFILGASAGPFHKIGHNSELMPNVLLEksADEgfKIRNDLTHL---aeiHDQNN-----R-FRLLksDHSEFGLLGDLFVSEGKPGKVLRIEVQNRKIidnndindeEkASFTTIIRKILQESYPNq-LISLGGVFLIEQGEAILHIMP-DFSDVPLNTEQEVNDWLRFFPMKSPLRCLTTMHSVVDgYRNLRSEHTHCFSdhn---QGGHYHNDIdp--KRIKYLAYLNTAKIIYRIDKPSITNISK-- +>tr|W9DVQ5|W9DVQ5_PELUQ Uncharacterized protein OS=Candidatus Pelagibacter ubique HIMB083 GN=Pelub83DRAFT_0385 PE=4 SV=1 +--KGTFTNHSLEDIASALKKGLSENFKNVEVEVVDCPNLRE--WDCPSEGISGNQKIIDVGGEPYMHDPNFIGAEFDYEEISKMIGsEKs--YALGAGSGAMSCLDGHCGeLVINENLItdE------SRSII---arvSPDK-------KCIVEkySARKHGGLGNIYYTDGKQGKVIKIKIRGRSGDqGSLPQVMRSSLSKNLKIkdnEHLSLAGVFRVLNGKIRSHVQP-DYKDIKheyYdpKQMKCVKDFLQFYEPvGPKLQCYTVLWTGDPtGGELNLresgEHThfHSYEhd--KDAGHYHFD-vTPEEIEYEGYFNTATEVHRVNNIYKELLSKNS +>tr|A0A0C9Q6Z5|A0A0C9Q6Z5_9HYME CK054 protein OS=Fopius arisanus GN=CK054 PE=4 SV=1 +--QRQLFAPSLQEIKNVLSPALAENFSEVSIEVVDCPDLTQQPFTLAAAGLGGSKTILEVGGPSFLLPSVQRDKVYELKSILNRINnGKmEkkGFVIGAGAGPWPRLSRNCEMMMNVIVSpT---DLKNETRL---swvGPNE-KCILe-ESLEN--DLRFALLANLYLSEGKPGKVLKVHAKKRTGNLDFIATMQKALESHY-KdKLVGLGGTFLLKQGKAKQHVMR-DFSSVPLTTEKALNDWLKFYDMSAPLIAVGTFVSAETDLDLRVQHFHSFSHHGEGGHYHIDTTPETVEYLGYFSVAELLYRIDQPAVGVTFGKD +>tr|U4UGN1|U4UGN1_DENPD Uncharacterized protein OS=Dendroctonus ponderosae GN=D910_06428 PE=4 SV=1 +--TKSLYQPPLTEVAEVFRSYLPTNFQEVNVSVVECPDLTSKPFLLAAGGLNGNAKLLEIGGTQYLLPLVTREKLYDLLDIAKSVAl---epAFLIGAGAGPHPFIGGNCEGIVNLKIEkG---VADQQTRT---skvEGAdE-YMVVq-ILPNN--ETRIALLGNIFASEGKPGKVIKVHVKKRTGAKNFIETLRNAIEEKYGKdQLVGIGGAFLIAEGKAKQHVMR-DFSKTPLTSEDDVNNWLKFYEMSAPLTALGTFTSNDGaDLDLRVQHFHSFSTHGEAGHYHYDTTPDTVEYLGYFNVAQEVVRVDKPESGSKLGRD +>tr|A0A150UWN0|A0A150UWN0_9PEZI Uncharacterized protein OS=Acidomyces richmondensis BFW GN=M433DRAFT_7096 PE=4 SV=1 +--VHPLSPPPLDELARVLTSALEENYAYASATVVDCPDLSLSPFYLAGSGLCGCECVADIGGQPHLFPRPKLDKKYSLIECARDMKmNP-eyGMLIGAGAGPFHVIGGNSELASNLSWSggFNN--VQNLTRF---akiN--------gtaEIMVRKSPSTDCALMMNLFGSSGHSGHVLKIMAKSRRGSeKSFTECIRRALNNTYGSsTQISMGGVFLIRKGKALFHIMP-DFPNEDrlpFKDRHDLn-RWLTYHGFSAPIVCLTVFHSADPeSLGLRMEHTHCFStek--NEGGHYHHDLppdeADlEEIEYEAYLNTAKTLYRIDQPETFLGQHHR +>tr|G6CSG4|G6CSG4_DANPL Uncharacterized protein OS=Danaus plexippus GN=KGM_07584 PE=4 SV=1 +--EKSLHAPPLEEIVEVLSQKLPSNFEYVRVSAEESPDLTRSPYNLTSPGLCGDAKLVELGGPPYLVPTVRRDKLYSLTDLLRHLRr---dpALLAGAGAGPWPYLGVNCEGIINVYVKdS---AVSQGSHV---vsvSPVgapkgQSSFVQe-KLPAS--ETRTALLGNYLLSNGEPGMVIKVVAKKRIGEKNFITAIREALKEHY-GdKVVGLGGTFALLEGRAKHHVMP-DFSATPLCSDSDVDSWLHYFEHSAPLAHVGTLVTGDLGLDLRVQHFHGVSEHGQGGHYHYDTTPLAAHYEGYFTVAGSVIRVDAPENTHAIGRD +>tr|B3PAK2|B3PAK2_DROER Uncharacterized protein (Fragment) OS=Drosophila erecta GN=Dere\GG19819 PE=4 SV=2 +--EKPLYVPPLSELQNVIQVALAANFANVDVSVGPCPDLKAKQFGLVESGLGGKPTLLEAGGPPFLLPLVQRDKLYNIAEMTRKIQgP-GtVFAVGAGAGPWPIRGSNCEGIFNLSVNeKD--ELTNGSYT---atvRGEQEECVLe-KIPHT--EPRCALLLN------------------------------------------------------------------------------------------------------------------------------------------------------------ +>tr|A0A1B0ESX2|A0A1B0ESX2_LUTLO Uncharacterized protein OS=Lutzomyia longipalpis PE=4 SV=1 +--SKDLFIPDNKELKEALTIGLKKNFQEVSVDFVECPDLSGAPFNLANSGLCGNATIVEYGGAPYLLPLVQRDKLYDINEICLKICrERqMshYLAVGAGAGPYVLCNSNCEGIFNLAGGlDG--KIVSKSHL---alvDK-DKQCERr-NIPAS--ETRTALLGNIYLSEGKTGQVLKIHCKKRTGSNNFITQIRESLASHFVDKDIGLGGTFLLKSGKAHQHVMQ-DFSVTPIYTEEELNTWLKFYDMPAPLVAVGTLVTNEMDLDLRLQHFHSFSPSHWGGHYHYDTTPDTVEYEGYFGIGEKLYRIDKPKETHKFGRD +>tr|A0A084WLJ3|A0A084WLJ3_ANOSI AGAP006729-PA-like protein OS=Anopheles sinensis GN=ZHAS_00019143 PE=4 SV=1 +--EKALHTPSLGEIRDVLATGLKSSFATVNVEVVECPDLTKAPFHLAGRGLNGSPTLVEIGGPPYLLPNVDRSKLYDLVSVSQRALhD-tKkeFIAIGAGAGPFPLVNSNCEGMFNLRYTpPG--TVVSESHL---aviSPTDRTVTVh-KIPNT--ETRCALLGNILVAEGKPGQVLKVSCKRRTGKKDFIASIRTCLEGHYGERTVGLGGVFLLQTGKAKQHVMS-PFSETPINTEEELNEWLNFYDMPAPLINVGTLVTTECDLDLRLQHFHSFSTHGHGGHYHIDTTPDIVEYEGYFIVGERIVRVDKPVNTHKFGRD +>tr|A0A171AA04|A0A171AA04_TRIIF Ester hydrolase c11orf54-like protein OS=Triatoma infestans PE=4 SV=1 +--SVKLDCPKLEDVANALQKGLPQYFAETEVAVVDCPDLREEPFNLAAKGLGGKTVVIDIGGPGFLFPLHDETKIYDMKkDIANTVGm---ksCFIIGAGAGPWPYIGKNCEMMANILINdsTSS-I-VQKTYI---akv-NDkTEDIEVe-LLPNS--EMRFSLLANLFACEGTSSKVLKVFCKKRKQDENFITSISTTLEKAF-PnKTLGLGGTFLLKEGKARQHCMP-EFSKVPIRSNDDLNNWLKFYEMSAPLVAVGTLLSKDIpDLHVRVQHFHSFSNHGEGGHYHYDTTPETVEYLGYFNLGQTLCRIDQPEKKQYFDKN +>tr|A0A0K8TRB6|A0A0K8TRB6_TABBR Putative ester hydrolase c11orf54-like protein OS=Tabanus bromius PE=2 SV=1 +--EKPLHVPTFEEVQEVLLKELPTNFAEVSVEVVDCPNLSNPPFHLVKPGLNGSPTLIEVGGAPYLLPLVDRSKVYDIEKVARKAVgK-dVdLLAIGAGAGPYMLPGVNCEGIYNVNVKrDG--TLESGSYY---syvKGTEESCQAv-KIPHN--EARFALLANIFASEGNPGKVLRVYCKTRTGNQNYIESIRLALAKKYPEQCVGLGGAFLLKSGAAKQHVMR-DFSTTPIHTEEELNTWLKFYNMPAPLVAVGTLVTNEYDLDLRLQHFHSFSKSHWAGHYHIDTTPDYVEYEGYFTFGEKIVRVDKPVNTHKFGRD +>tr|A0A0P7B8H3|A0A0P7B8H3_9HYPO Uncharacterized protein OS=Neonectria ditissima GN=AK830_g8244 PE=4 SV=1 +--KLALSPPPLSDLATAIAAGLRTNFTTSTVSVSTPPDLRNAPFFLAGPGLSGNARVADIGGVQNLRPTPNLDAKYDLLGIARLMGmSDe-gGLLVGAGAGPFHHLGYNSELMPNIAYGsaSD-GVINNCTHY---akiT-QDG----gVRCEKIGESVGFALMANLFGCDGETGPILHVTARGRKARQSFTESIRAGIRAVYGDk-LVSLGGVFVIHKGKTKLHVMP-DFSDKPLRSPDDLDGWLRYFDTDPPLVCLSVFHSGDDgDLGLRMEHTHCFAgeggaVDCRGGHYHGDVdeTMQDVEYEAWFNVGEVLYRIGQPDGE------ +>tr|T1HIK3|T1HIK3_RHOPR Uncharacterized protein OS=Rhodnius prolixus PE=4 SV=1 +--TLKLDCPELEEVANALQKGLTQYFAEVEVAAVECPDLREKPFNLAAKGLGGKSAVIDIGGPAFLLPLPDESKIYDIKDIAKIVDlKS-CFVVGAGAGPWPYIGKNCEIMANVLIDscANStV---QKTHI---akvNNKTENCEV----EVLpsEETRCTLMANLYACEGTPSK-------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|A0A060WWJ2|A0A060WWJ2_ONCMY Uncharacterized protein OS=Oncorhynchus mykiss GN=GSONMT00039591001 PE=4 SV=1 +--KFQLYVPILEELCDVLQRGLKNNFADAQVCVVDCPDLTQDPFKFPVKGLCGKPRITDVGGVPYLVPLVKVDKEYNMNTVSKEL----------elpgafilgaGAVSSKNVGMNAEMMPLVLTEaeGR--PAVNS------swfssiNPDNNQCLLe---KYSDkfSDCDFGLLANLYACEGKPGKVIEVRAKRRIGEESLVGALRKTMEEHYPDk-SLALGGTFLIQKGKAKIHIMPREFSACPLNSNDDVNKWLKHFEVSAPLICQSVMVSRDPGLDLRVEHTHCFSHHGEGGHYYIDTTPDTVEYLGYFMPAEFVYRIDRPSETHEVGRD +>tr|C3YJ39|C3YJ39_BRAFL Putative uncharacterized protein OS=Branchiostoma floridae GN=BRAFLDRAFT_126899 PE=4 SV=1 +--RKEAFVPPLDELASVLQAGLSSNYLDAKVKVVDCPDLTQPPFTLAAPGLCGSPRVADVGGVPYLIPSPQLDKKYNLEQVAGQV----------dlpgafvlgaGAGAAHVVGVNCEMMPNIRTTggAH--SRNNQ------trvsrvNTEDGTCILe---HYEDtyQCRDFCLLANLFFCEGKPGKVLEVKAKVRTGQENFVSCMRKTLEQQYGDr-PVALGGTFLLEKGQAKIHIMP-GFSKTPLQSEEDVNNWLNFFEMSGPLINLSVFVSRDPGLDLRVEHTHCFSHHGEGGHYHYDTTPEEVEYRGYFLPAEYIYRVDRPKVSHMIGRD +>tr|A0A177BUL9|A0A177BUL9_9PLEO Uncharacterized protein OS=Paraphaeosphaeria sporulosa GN=CC84DRAFT_1132340 PE=4 SV=1 +--KVPLSPPTLREIAVALQFPLAANYSHSTVDVVQCPDLRKAPFYLATAGLSGAEKISDVGGQPNLFPTPRLDCKWNLLDIARAMEmAP-hgGGLLGAGAGPFHIVGHNCELVPNIAWNdgFE--NATNSTYL---aqiRQ-------gEPSVEKSPSLDCALMINLYGSLGHSGPVIKITARGRVGDeKSITELMRKALANAYGDRMVSLGGVFAVKKGTSKYHIMP-DFPPEEelpFKNAKQLn-DWLTYHEFEAPVVCLSVLHSADPgkKLGLRMEHTHCASmdgr--DVGGHYHGDIng--EEVEYEGYFNVAKTLYRIEKPEVTLERDLH +>tr|D6X2L2|D6X2L2_TRICA Ester hydrolase C11orf54 homolog-like Protein OS=Tribolium castaneum GN=TcasGA2_TC010676 PE=4 SV=2 +--KKSLDRPPLEELAKVLNKGLQSNFEHVTVEVVDCPDLTQQPFTLAKKGLGGSPKLVEVGGVPYLLPLVKREKVYDLKKIATMIGs---dpAFIIGAGAGPHPYAGVNCEGILNMNIAkG---VVDQQTRI---skvNPSneE-VPIQe-ILPNN--ETRVALLANLFFSSGEPGKVLKIHAKKRTGPLDFIASIRQTLVNEY-KnKVVGLGGAFLLKEGKAKQHVMR-DFSKTPINTDEELNNWLKFYNMRAPLVAVGTLINNDHGLDLRVQHFHSFSHHGEAGHYHIDVTPETAEYLGYFNTGEEIYRVDRPVETHQFGRD +>tr|G1K3I6|G1K3I6_XENTR Uncharacterized protein (Fragment) OS=Xenopus tropicalis GN=c11orf54 PE=4 SV=1 +--NCSFHVPSLEEICSVLKSGLLKNFADVSVIVTECPDLSKEPFEFPVKGLCGKSRIADVGGVPYLVPKPRLDKVYNVNAVAKKI----------glpgayilgaGATSHKSLGMNAELIFSVQAEneSI--QAVNK------syvasvNPGDGSCLLe---KYRDrnNDNDFGLLSNLYACEGKPGKVIEVSVKRRIGQDNFVSCMRKSLKTHYGEk-AVGLGGTFLLKEGKAKLHVMPREYSACPLNTDEDVNGWLKFYEMKAPLICQSVFVSHDPGYDLRLEHTHCFSHHGEGGHYHYDTTPDTVEYLGYFHPAELLYRIDKPSATHMVGRD +>tr|C4WVQ1|C4WVQ1_ACYPI ACYPI24700 protein OS=Acyrthosiphon pisum GN=ACYPI24700 PE=2 SV=1 +--RFKLNTPPLRCIIEAILPELLDNFENASVEVVQCPDLTQPPFNLTSEGLCGDENVFDIGDVTNLLPSLKREKLYNVKDLKQITGsDP-LFIIGACAGPYPFFGADSECVENVKMTgdRVEng----THVHM---tksD-DVPECFH----KSLpdDEMRFSMMANFFTSNGFKGEVLKIVCEVRKGPLSYSTCIKEAL-VkHFGNe-IIALGGVILIENGKVKVHViKP-SLTKIPIKSEKELGNLLHFIELSPPLVGVGCIVSHDPGLNLRLQHFhl---Ytdhn---QGGHYYNDTePEt--IKYTGYFGVSKQFTKID----------- +>tr|A0A0C2IGB5|A0A0C2IGB5_9PEZI Uncharacterized protein OS=Sporothrix brasiliensis 5110 GN=SPBR_07633 PE=4 SV=1 +--KYELSPPPLDELAAVLQTGLQQHFESVSVHVTRSPELREAPFHLAAAGISGRERIGDVGGPQNLRPLPRLDHKYHLREIMDLMEmQD-GLVIGAGAGPFHHVGGNTELMPNLSYTdG---VANNQTRF---ariVPATETDSVrdiatgtlaHRCRPLPapKSADSALLTNLYASDGAPGDVLKMVAHGRKPDsPDFTAAIQDVLRSTYSQ-PVSLGGVFVLRRGRALLHVMS-DFKTEP-RLPGNQDNWLTFFDVAAPLTCLSVVHARDPGLRLHLEHTHCFSerg---EGGHFHHD-sTPADAEYEAYFNTAKVIYRIDGPGE------- +>tr|R4WD98|R4WD98_RIPPE Uncharacterized protein OS=Riptortus pedestris PE=2 SV=1 +--SRDLHVPSLEDAQKALSKGLKNVFAEVSVDIVDCPDLSAEPFNLACKGLGGTTSVVEVGGPPYLLPKVDRQKVYDVKDIVKAIGl---qqCFVIGAGAGPWPFIGKNAEMVANVYIDgnNVK----SLTHI---aklKDDgTNNIEVs-VLPNT--ETRFALLANLFFSEGVQSKVLKVHCKKRTGSDNFVTAMRNALHDDF-PdKVVGVGGAFLLKSGKALQHVMP-DFSKSPLNSDEELNKWLEFYSMSAPLVAVGTLVSSDIpELDLRVQHFHSFSSHGEAGHYHQDTTPNEVEYLGYFNLGQKIYRIDKPPLTHSWGRD +>tr|K4FSW3|K4FSW3_CALMI Ester hydrolase C11orf54-like protein isoform 1 OS=Callorhinchus milii PE=2 SV=1 +--KFSLHVVGLEELCEVLQDGLKTNFAEVQVTVVDCPDLTKEPFTFAAPGICGNPRLADVGGVPYLIPVPQTQKVYNLNAVAQDV----------qlpgafiigaGAVSSKAVGMNGEFMPNIITEkdGK--PAVSH------sycatiNPANGKCVLe---KYTEtyKTMDFEMLANLYISEGQPGKVIEVKATRRTGESDFVKCMREALGYRYGDk-PVGMGGVFIIQKGKAKLHVMP-AFSSTPLESDREVTKWLKFFDMNSPLICQSTFVSHDPGLELRVEHTHCFSQHGEGGHYHYDTTPNIIQYLGYFLPAEHLYRIDRPNKSASAAFD +>tr|A0A0G4GDI3|A0A0G4GDI3_VITBC Uncharacterized protein OS=Vitrella brassicaformis (strain CCMP3155) GN=Vbra_17462 PE=4 SV=1 +--RHKLDPPPLDELANALSDGLARFFADVLVEVVDCPDLTAAPFGCAFSALGGDPCIIDVGGVDNLFPCARRGKYFDLSAIEQQIGaGRs--CFIGAGAGPFQEVQHNCEWICNVRLPeaNES-------RC---avmEGTDK----GSGYTIErpKTTCFGILGNLYACKGEPCKVLHIKAGRRTGkdpSgKDLPQCLASILASSFPSr-PVSLGGVMAMHAGKARLHIMS-DFTDDPIRSNDAIENWLNYFEVPAPMTFMFVSTSIDPGMDLRTVHTHGWHegk---YGGHYHND-tTPDEVSYEVYVNVAECIYRIDRVSQTPDFNRP +>tr|A0A0L8G520|A0A0L8G520_OCTBM Uncharacterized protein OS=Octopus bimaculoides GN=OCBIM_22000243mg PE=4 SV=1 +--KLPLKIPDEAELVSVLSKGLLKNFQDVSVNIVDCPDLREKPFQLAAEGICGNPCVADIGGPPFLLPTVHKEKIYNIKTISEISGQQDGFFIGAGAGPAHLIGVNSEMMCNVNLNkPD----GCQTYIAKVnPE-NGCFNLk--Q-IE--HSSFMLMANLLCCEGKQGKVIEVKASKRIGDDNFPTAIRKTLKSQYGSEPVALGGVFIIENGKAKLHIMP-DFSCKPINNVTELNNWLRFYEANAPLVCLGELISHDPDLDLREEHFHCFSPHGQGGHYHYDVTPEEVSYRAYFSVAKTLYRIDKPEHPLNFGKD +>tr|V4AUJ8|V4AUJ8_LOTGI Uncharacterized protein OS=Lottia gigantea GN=LOTGIDRAFT_214298 PE=4 SV=1 +--KADLHVPTLEEAAKVLEKGLKNNFENVSVSVVDCPDLTQKPFNLSSPGICGNERLADVGGPPYLVPQYNKDKIYDVGKVSEEVGLPGAFVIGAGAGPWPLVGVNSEMICNVKLGkNG-QPTVNNTYIAKVgEK-DGKCQQm--QIKD--STEFCLMANLLCSEGKQGKVLQVKASKRTGPENFMSSLRKTLDSHYENKSVALGGVFLVETGKATLHIMP-DFSKVPLKSDGEVDEWLQYFEMDAPLVCLGELVSRDVNLDLRTEHFHCFSDHGQGGHYHYDTTPDTVSYRGYFTIPHSVYRLDQPKSNISM--- +>tr|E0VTT7|E0VTT7_PEDHC Putative uncharacterized protein OS=Pediculus humanus subsp. corporis GN=Phum_PHUM437900 PE=4 SV=1 +--TFDLSIVPLEDLAAGLNEHLKYNFEKVKVEVKDCPDLTQPPFTLACKGLTGNERIVEIGGVPYLLPKPRKDKLYDLKDLSKILNl---dpCYITGAGAGPWPYAGTNCEMIINMEHNgD---KVNNKTRI---akvNVTdG-KCIQe-VLPND--ECRNAVLSNLYCSSGEQGKVLEISCSKRIGNDDFITSIRKILGENF-KdKILGLGGVFVIKKGKVKQHVMP-DFSNREISSEDDLNKWLKFYEMNTPLIAVGTLVNNDPGLDLRVQHFHSFSHHGEGGHYHIDTTPNDVEYLAYFGLGEKLYRIDRPSQTHNYGRD +>tr|U6NKE0|U6NKE0_HAECO Uncharacterized protein OS=Haemonchus contortus GN=HCOI_00338900 PE=4 SV=1 +--IIETLKPSNEELLAIFEGALKENFKDVEIKLCQCPDLTAEPYNMTSTGFGRKMVIAEVGGPGNLFPVIHKEKDFDLKEICNGCEaPAs--FVFGPGAGPWQVVGRNCEMVADANFSssK---VA---TKI---aslPPG------htPTAYKMEviSSPKFSLMANLAVSAEpGPAQVVYCKASVRTGKDNFPETIRKGLAKHYGDk-CVSVAGVFMMLKGEAKLHVMP-DFPGCNFSSREELeKQWLRFFTMKAPLVCASVFHSYDPGHKLRMEHTHCYSshg---DAGHYHYD-tTPDTVVYEGYFTAAEKIYRFDEV--------- +>tr|A0A131YK09|A0A131YK09_RHIAP Uncharacterized protein OS=Rhipicephalus appendiculatus PE=4 SV=1 +--KHQLHCPSLEDVAKVLNDGLKSTFEHVEVSVVDCPDLKEKPFMLASEGICGKPCLADVGGVPYLVPIVQKDKIYNLEQVVKQTNISDPLVIGAGAGPFNVVGVNSEMMHNMK---YGDKPFNNSHYAKINE-DGSYELGRFTTS--CCEFGLMANLMISEGKPGKVIRVSAKKRTGADNFVTAMRKALAAHYGTNPVGLGGAFLLAKGKAKLHVMP-KFSTAPLLTNEAMNSWLKFFEMEAPLVCLSVFVSHDPGWDLRIEHTHCFSDHKQGGHYHYDTTPEEVEYLGYFNVAECMFRIDAPASTHQIGRD +>tr|W2RXT3|W2RXT3_9EURO Uncharacterized protein OS=Cyphellophora europaea CBS 101466 GN=HMPREF1541_03070 PE=4 SV=1 +--KRELSPPPLDELAGIIAAGLESNFEQSSVQVEPCTDLRKAPFYLAGEGLNGSTRVGDVGGPPHLAP-PDFSKKYDFMEISKLMEmPQe-kGFLLGAGAGPFYVLGCNAELIPNISY-EN-GEITNLTHY---akiA-KDD----qVECQKIETSTGFAFMANLFGSEGLPGPALHIKASSRKGAPNFTETIQAAVQEKYGDk-LVSLGGVFVIKRGRANLHVMG-DFPEKPLQ-RQDVDDWLRRFEFDAPLICLSVLHTGDDqGMALRPEHTHCFSvgg--KNGGHYHFDVedTKADVEYEAWYNVAEAVFRIDSPGRRY----- +>tr|A0A0X3PUS6|A0A0X3PUS6_SCHSO Ester hydrolase C11orf54 homolog OS=Schistocephalus solidus GN=CK054 PE=4 SV=1 +--VLRTFEASLEDIAAAFETGLKSCFQNVSVSVADCPDLTNKPFALPSSGLLGNNTVCDVGSFSYLIPVADTSRRYTFSEVISASKlQT-GQLIGAGAGPFFTAGKNCEMAAIVKVAenD---VRSNNTLH---gvyNKSED------KPGVLkaTDNNFALLGHFLATEGNPGKVLAVDVSVRAKDGSIYTFLREALTAKFGNesAPVALGGAFVLDNSKGRFHVMP-DFPKEPVDSPAKISSWLKFYEMSPPVMGVGTIVSHDPdKMDLKLEHFHCYSenga---EAGHFYYD-tQPETAHYRVYLAPAKSILRIDRAIK------- +>tr|A0A0P4WGG9|A0A0P4WGG9_9EUCA Uncharacterized protein OS=Scylla olivacea PE=4 SV=1 +--HKPLHVPPLEEVSSVLEAALKKNFAEAAVSVVECPNLTKTPYNLGAAGLCGSPRLADVGGVPYLMPTAQKDKLYDIKDLAGCVDLPNSFIVGAGAGPHKYIGVNSELMANVV---VGNEACNGSRAAKVDD-AGKCELLRLPQE--QTGCALMLNMFASEGKGGKVLKVQAKKRIGDKNLVSCLRQALENHYGDQPVGLGGTFRLLQGKAKIHVMP-DFSPVPLTCDNDVNKWLNFYDMEAPMVFLSTLISRDPGLDLRVEHSHGYGD-DRGGHYHYDTTPDTVEYEAYYNVAEFIYRVDKPVATHGFGRN +>tr|A0A087T5J9|A0A087T5J9_9ARAC Ester hydrolase (Fragment) OS=Stegodyphus mimosarum GN=X975_12710 PE=4 SV=1 +--KHNLHKPNLNEVAKVLQAGLSNTFSHISVDVVDCPDLKGKPYMLAAEGICGNPCLADVGGVPYLIPVARADKVYNLREIAKQIELPNALIIGAGAGPRHHVGTNCEMMPNIK---FNENEFNNTHIAKIGK-DGNCELVHLKD---SEEFCLLGNLFASEGKSGKVIKVTAQHRMTSENFVSVMRKTLAEHYKDQPVGIGGVFNIQVGKAKLHIMP-DYSKTPLKTDEDVNNWLKFYNQPAPLICLSTFISHDPGLDLRVEHTHCFSDHDVGGHYHEDTTPDIVKYEGYFNVADFIYRIDPPAETHQVGRD +>tr|A9UWD0|A9UWD0_MONBE Predicted protein OS=Monosiga brevicollis GN=20550 PE=4 SV=1 +--SRDFHVPSLDEVAGVFEAGLRANFATATASVVDCPDLTQAPFHLASEGICGSPRLADVGGVPNLVPLVNRDKVYNFVDVAKQIDLPGAFFLGAGAGSSRLAGVNCEMMPNTHIAtH----TI-KSYFAKVdPE-DGSMVL--NPYS--SNEFGLLGNFLASEGRPGKVIKVEAETRTGDKNFVTCMREALHAHFGDaMPVAIGGSFVIEAGNAKLHVMP-DFSKTPLQSDDEVAQWLKFYECQPPLTCLSVFVSHDPGMDLRVDHTHCFSQHGQGGHYHYDVTPKAVKYTGYFVVAEKVFRVDAPKETHTIGRD +>tr|A0A0B7ARP3|A0A0B7ARP3_9EUPU Uncharacterized protein OS=Arion vulgaris GN=ORF132368 PE=4 SV=1 +--KMALHQPSLSEVAEVLQKGLAQNFSFSEVSVVDCPDLTKPPFDLAAEGLGGQPRIVDIGGPDYLKPWPQKNRLYNFESIADLAELPGSFLIGAGAGPHLNVGVNCELVCNAKLGlNA----RNRTRIVKVdEK-VGTFKLe--E-ET--SGEFSLMGNFLISEGKPGKVLEIKAKNRTGTENFVSSIHKTLTAHYGDKAVGVGGTFLFQTGKANIHVMP-DFPTTPFENNEQIDSWLRYYEMDAPLINVGEIVSADPeNLNLRREHFHCFSNHGQGGHYHYDTTPDNASYLAYFNLGEVLYRIDLPEAK------ +>tr|A0A163MLZ4|A0A163MLZ4_DIDRA Nucleus OS=Didymella rabiei GN=ST47_g4 PE=4 SV=1 +--KIDLKPPPLEDLIDCIRSGLGQSFKSISVSVDQCPDLRQAPYHLAFTGLCERPRIADVGGQPNLAPTPDLTKKYDLLEIARLMEMPEgqGALLGAAAGPFHVVGMNSELMPNLSWKnK---EVSNETHFAKVRS-DGSAVC--EKLS--SHDCGLMANLFGSLGRPGPLLHITASSRTGPLNFTEAIRGALQDAFGTRTISLGGVFLISEGKAKLHVMP-DFSPTPLVTDKQKEEWLKFYEMKAPLVCLSVLHSHDPGLDLRIEHTHCFSDHGEGGHYHYDTTPADVKYEAWFNIAEVLYRIDRP--------- +>tr|Q5BYZ9|Q5BYZ9_SCHJA SJCHGC06040 protein (Fragment) OS=Schistosoma japonicum PE=2 SV=2 +--EFVLHKPSYHEVSAALESHLKDCFESVKCSITDCPDLSDTPFCLTLKGLCGKGTICDVGSFDYLLPVPKTDRHYDLLDVFKSAGiTV-GAVIGAGAGPFFLTGSNSEMVINISSEngK---VSKNSSLL---gsyDKENN------KPLITkaDNTKFALLGQMYMCEGKSGPVIELCVSGRIRDGKLDAMIREALHKKYGHlsSSVGLGGVIIQEKGKSLYHVLP-EFSQEPIDSNEKLRNWIKMFEMESPVISVGIVVSHDPhHLGLRLEHFHCFNqdht---NCGHCHFD-tHGPSVSYRAYFALAEHLVRIDQPK-------- +>tr|T2M672|T2M672_HYDVU Ester hydrolase C11orf54 OS=Hydra vulgaris GN=C11orf54 PE=2 SV=1 +--EKELFQPPLKEVCDVFLSGLLKNFKNASVTIEECPDLTKEPWTLASNGICGTPYLLDVGGVPYLTPNPQFHKIYNYETIAKVLPFDNVLILGSGAGPFHKIGYNCELMANMYISkV----FKNESRIASIDK-NGSYEL--QINQ--EKEFGILGNFLASEGVPGKVIKVNASVRKGGKNFIECIRESLRAKYPDNMIGMGGVFVIKSGKAKIHVMP-DFSCSPLNTKEDVDNWLRFFEMSSPLVCLSVFYNIDQGMDLRIDHTHCFSHHGDGGHYHFDTTPDDVSYEGFFVLAEKVLRIDRPC-------- +>tr|A0A026WXA5|A0A026WXA5_CERBI Ester hydrolase C11orf54-like protein (Fragment) OS=Cerapachys biroi GN=X777_14112 PE=4 SV=1 +----------------VLERGLSMNLKKVKIEWMDCPDLRL--YGFVAPGLCGTPALLEIGSLSYFCPTPRLDKKYYFRELLSLLNlTGq-dNFIVGAGTHIDPPT-----------------------------------------YDLaeFNSLCVIQGNFFLSERRPGKVLQVTAHCRTGPLNFVSAIQELFNLmrTETDp-LIGLGGMFMVSGSPTLHHImPA-YSRVTNLYTMKQVQQWLRYRKLIEPVTAVGTIMISLLLMdahdysrffqlpYLTKSHFhsHTLNqprs---CGGHFYTNCvnTNyLDAFYVGYFSFAEKLYCVDPPSRRDIHTNI +>tr|A0A0M9WC82|A0A0M9WC82_9EURO Uncharacterized protein OS=Penicillium nordicum GN=ACN38_g9838 PE=4 SV=1 +--KHLRDPPPLDELAAVIEKALLSNFKTASAIVAECPDLKQQPFNLAASGLSGSPRIADIGGQQHLFPRPNLNAKYSLLSLAQDMEmSP-kaGFLLGAGAAPFQDIGQNAELAPNLSWRsnS--napgfddpslLTFDNGTRV---ikvQRDGD----gdhTPLCDRTSSTNCALMANLFGSDGGTGPVLKINARARKGDe-NFTDCIRYGLQKVYGDsKPISLGGVFLLKSGKAKFHIMP-DFPPEDqlpFRDRRQLeTEWLSYHIFQAPVVCLTVMHSSDPdGLGLRMEHTHCFGangt--TKGGHYHYDIqdgd--EEVECDPSYLLKNILKDV------------ +>tr|A0A0N4U0N2|A0A0N4U0N2_DRAME Uncharacterized protein OS=Dracunculus medinensis PE=4 SV=1 +--------------mfcnWTWIKGILWNdsgGYRKMPSHKYQVSDFRQAPYLMTGSGIGSGLRIVEVGGIGNIYPVIKCDKFFDLKAICTKSDmPNa--FVFGPGAGPWHVIGSNCEMVADANFVnpS---NPVIASKI---iki---------nadNKAYELSttNSSYFSLMANLALSNAnEPADVVHIHVKKRLTDTNFPESVRRTVGAYYGKn-LVSIAGIFLVKAGKIKMHVMP-NFPSPNYcwKSADEVREWLKYFEMSAPVICACVIHSTNNeERKLRMEHTHCYSehg---DGGHYHCD-lSPEIVEYEGYFAPAESVYRIDLV--------- +>tr|A7SA42|A7SA42_NEMVE Predicted protein (Fragment) OS=Nematostella vectensis GN=v1g110650 PE=4 SV=1 +---------------TVLQDGLTKNFSHATVTVVECPDFRQPPWNFPAT--GKNLLIVDVGGPAYLLPLPQLNKIYDMNDVAAKADLPGGYVIGAGAGSHTSVGVNCEMIANVCTGtET-SNPVIQSKITKVnPE-DGSCVFq--D-YD--VCDFSLLANCLITEGKPGKVLKVEASKRTGDENFVTCMRLALGSYYGNRAVGIGGTFMIAKGKANFHIMP-EFSKTPLNSPEEVNNWLKFYDMSAPLVCLGVLESYDPGLDLRVEHFHGYNNHGEGGHYHYDTTPNEVEYVGYFTPAERLYRMDRPPKL------ +>tr|F2U224|F2U224_SALR5 Uncharacterized protein OS=Salpingoeca rosetta (strain ATCC 50818 / BSB-021) GN=PTSG_02390 PE=4 SV=1 +--SQVLETPPLEDVAKALETGLKGCFEQASVSVVDCPDLTAEPYHLAAPGISGSTRLVDVGGVPNLMPLVDRSKVYNFKQVAKDIGLPGAFFIGAGAGSSRLAGVNCEMMPNTNIAtQ----EI-RSYFAKVrPE-TGDMVL--EHYE--SNEFGLLGNFLASEGKQGAVLRVEASVRTGDDNFVTCMRQSLQAAFGDKPVGLGGVFVIEAGDAKLHVMV-RGVHCAA-------------------------NGDAVGWILRVEHTHCFSQHGQGGHYHYDTTPANVKYVGYFSVAEHIYRVDAPKVTHQIGRD +>tr|A0A194X4L4|A0A194X4L4_9HELO DUF1907-domain-containing protein (Fragment) OS=Phialocephala scopiformis GN=LY89DRAFT_620264 PE=4 SV=1 +--THPLPPTSLSNLISPLLTSLKQNFTDATISLVPCPNLTQPPFHLAAPGLSGHEAIVDIGGPAYLHPVPDFSKKYDLGRIVASLSsGEekGkgRLAIGAGAGPFHIVGQNSELIPNFYISaS--gNVTKNLTHY---akiDPSTQ----tCIAGPVPgASTAGALMANLFLSDGDPGPVLRITARNRIGDKSFTEAMRMGIEE----REISMGGVFVVEGAKVWAHVMP-DFCGER-LEDAEVGKWLRFFEWgGEGLVFLSCFHGVDFGVGVRVEHTH----------------------------------------------- +>tr|A0A017S4R7|A0A017S4R7_9EURO Uncharacterized protein OS=Aspergillus ruber CBS 135680 GN=EURHEDRAFT_518530 PE=4 SV=1 +--EITRHQLSLHELAEVLESALPKNYVTSSTTVVDCPNLPQSPFSLACEGLSGCQVIADIGVQPSLFPQPRLDEQYSLIVCVRLMGlDPe-qGAVVGAGAGPIHVHGTNSEIAPNLSWQgG--fGNVDNLTRA---arlVTTLA----gsrtRICCPYSDSTECLLMMSLYGSMGLPGPVLKVTARGQRGEsNSFTEFMRSALQDIYAQt----------------QFHVMP-SLPHSDelpFKSQAALDGSLSYYDISAPMVCLLVFHSADPnQLGVRMEHTQFQQg-------------------------------------------- +>tr|A0A1B6KUZ4|A0A1B6KUZ4_9HEMI Uncharacterized protein OS=Graphocephala atropunctata GN=g.45688 PE=4 SV=1 +--QKPLYCPSLDDVAQALKVGLSENFETVEVSVVDCPDLTQKPFSLASQGLNGSTTILEVGGVPFLMPLVDRSKVYDFKDMNQVTGv---npAFIVGAGAGPFRHAGVNCELVANLVVKdG---QVSSMSQI---aklKDEskGNEFVTe-TLQDS--VSTFALLANLFVSEGKPGKVLRVHCAKRKGKADFVTAARESLLKGF-PgKSIGVGGTFLVSGSKVKQHIMA-DFTSTPLDSEEKVDNWLRFYSMSPPLVGLGTFVTNDPGLNLRVIHFHSLSDHGEAGHYHYDTEPEKVEYLAYFNLGAKVVRVDRPQDESKLGHN +>tr|A0A1B6EDV6|A0A1B6EDV6_9HEMI Uncharacterized protein OS=Clastoptera arizonana GN=g.17798 PE=4 SV=1 +--EKSLAQPPLNLIAKAINDGLTKDFEYVQAEVVDCPDLTKAPFHLAAEGLGGSETIVEFGGVPYLMPLVQRDKVYDLKDLIQIIGi---dpVFVVGAGAGPHVYVQKNSELVTNISISkN---NIINLSRI---aklKDEqlNNDFEV-EILKE--ETRCSLLANLYTCQGKSSKVLKIHCKKRIGKNDFVSAVKQTLASTF-KdQCIGMGGTFLITGSKAKQHVMP-DFSKTPILNDDQVNEWLRFYEMGPPLVAVGTFVTKDPGLDLRLQHFHSFGtneSHPEAGHYHIDTNPDTVEYLAYLNTGSKVVRIDRPHETHQVGRD +>tr|A0A1C1XPK4|A0A1C1XPK4_9PEZI Uncharacterized protein OS=Diaporthe helianthi GN=DHEL01_13389 PE=4 SV=1 +--RVLLQPPSLNEVAAAVHNGLGSNFGTWSASVSTPPDLRQPPFHLAGRGLSGNPRVADIGGQSNLFPEVNLDKRYDLLKLSKQMEm--t-sGVLIGAGAGPFFDLGRNIELMPNIAFGsaSD-GDVSNCTRY---akvL-DDG----sALCEKIGTSTGCGLMCNVFGCDGETGSLLHVKAKGRTGKLNFTEAIQKGLADTYGDr-LISLGGVFVVCSGKLKMHVMP-DFPDEPLTSRQDVDQWLHWYDMDSPMVCLSVLHSGDDkGLGLRKEHTHCFGadagggeDSRRGGHYHFDLdeTTETVEYEGWFNVAEILYKID----------- +>tr|A0A1B6H7P9|A0A1B6H7P9_9HEMI Uncharacterized protein (Fragment) OS=Homalodisca liturata GN=g.15904 PE=4 SV=1 +--EKPLFVPPVEDVVQALQDGLASYFGSVSVESVECPDLTAEPFCLVTQGLCGSPRVVEVGGVSNFMPLYNPDKIYDLKDFNQLLAv---dpVVALGTGAGPFLDNHRCCELLANARISnG---EVQSLNRI---akvTNEnDRGYIVq-FLPKN--ETKFVLMANLFVSNGKPGKVLKIHCKNRIRDEDFPAAVRKCLAEKF-KgKELGLGGVFLVEGSKVCQHIPPEQFSKVPITSPEQLNNWLKFFNMNPPLVFVGTILTHDMGLEMILQHFHSFSSHGEGGHYHFDTDPHTVDYLAYFSLAEKAVHVDRPQCTStlKVDNI +>tr|A0A1I7RT80|A0A1I7RT80_BURXY Uncharacterized protein OS=Bursaphelenchus xylophilus PE=4 SV=1 +--KLDLLSPELEELAPILNVEMENYFQEIDVDIVDCPDLTKPPFNMTSRGFGPDLRIAEVGGVGNLFPKIRRDKLYNLKSICDLCElPNg--SVFGPGAGPRTSVGVNCEMVADANFGegT---VN---SKI---gkiDGQ--------SFVQEttCDPCFGLLANLGVSSGeT-DLVLKITARNRLTDYSFPHAIQQALFNHYRAk-IVSMAGIFIQKTGDAKVHIMP-DFPERDFSCWEE-eKSWLRYFKVRSPLICCSVLHSVNPGIDLRLEHTHCYSdhg---DVGHYYTD-iDPETAQFEGYFSPAKFLYRIDQIDSKGREK-- +>tr|A0A1B7YUZ9|A0A1B7YUZ9_COLHI Ester hydrolase c11orf54-like protein OS=Colletotrichum higginsianum (strain IMI 349063) GN=CH63R_00888 PE=4 SV=1 +--TFPLSPPSLEEIAAHLQAPLAANYTHASVGVVRCPDLRAAPFHLATEGLSGDEKIADVGGQPNLFPRPRLDTIWSLPEVARAIGmSP-erGGLIGAGAGPFHVLGQNSELAPNLGWSggLGEn-EIDNQSRV---iliERGSDGGDGttgkknAVSVRAAPSTDCGLMANLFASRGEPGPVLRIAARGRKGPeKSFTECIRQGLRAAYGGeRTVSLGGAFVVRAGRATYHVMP-DFPPERdlpFRDRRAVe-DWLTFHDFDAPVVGLSVLHSADPagGMALRMEHTHAFSaage--DAGGHYHFEAeg-EgDVIEYEGYFNTAKAIYRVDRPAGSS----- +>tr|A0A1I7RT20|A0A1I7RT20_BURXY Uncharacterized protein OS=Bursaphelenchus xylophilus PE=4 SV=1 +--VLDLAPPSLDELKAVIENGLHDYFVESSVTITDCPDFKTEPYNLEGSGLSPDLRIVDCGGHGNFFPKFQRHKQFDLKKISKTSElPQg--WIFGPGAAPRETVGVNAELVANANFNtnK---VN---CYN---grlTPD------GKGYLEGthSDTCFKMIANLALCSDeAGHRVLRISAKKRTGDGSFTEIIQKILASHYRNk-LVCLAGIWRFEKGRGYFHIVP-DYPEKDFEKLDDIwKNWLHFFELPAPMTMTTVIHSNDIGLDVPVEHTHGFSgrg---HCGHYHGD-vTPSEAVYDGYFLPATKLYRIDNTKHLS----- +>tr|A0A1S3J6D6|A0A1S3J6D6_LINUN ester hydrolase C11orf54 homolog isoform X1 OS=Lingula unguis GN=LOC106170181 PE=4 SV=1 +--KTRLYTPSLEEVAQVLQEGLSKNYSTVQASVTECPDLTKKPFMLAGEGLCGNPRLADIGGVPNLIPLAKREKIYNFEKIAGQLDLSNAFMIGAGCGPAHVMKVNTEMMPNLSVDgGGDGKVNNQTYLGRLnPD-EKSYDLf--V-SP--TTDFNLMANVFCSEGKPGKVIEVKVQKRVGEENFMSCMRKVLAAHYGTKPVALGGVFLVEKGKVKIHIMR-DFSKVPLNSDEEVNKWLTFHEASAPLVVIGELISHDPDLDLRVEHFHLFSDHGEGGHYHTDTTPDIIEYRAYLNVAEFMYRIDRPTETHNIGRD +>tr|W4Z4L2|W4Z4L2_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus PE=4 SV=1 +-------------MVNILQTGLKICFETAEVNVVDCPDLTQQPFHLAAPGLCGSPRLTDVGGVPYLVPLAQKEKKYNLDTVAEQVDLPGAFILGAgagphaavgtnnekynldtvaeqvdlpgafilgaGAGPHAAVGTNNEMIANIRTRsAD-SEGDNQTRLSSIlPE-DGSYCLk--C-SP--TRDFNLLANLMASEGKPGKVLEVKCQTRRSPDNFVSLMRHFIHKHYGKdKFIGLGGVFVIEEGKAKIHIMP-DFSKKPLDTEEDVNKWLKFFEFKAPLICCSVFVTHDPGMDLRLEHTHCFSHHGQGGHYHHDVTPKTVSYRGYFVPAEWMYRIDPPTITHNIGRD +>tr|A0A1L9Q4X5|A0A1L9Q4X5_ASPVE Uncharacterized protein OS=Aspergillus versicolor CBS 583.65 GN=ASPVEDRAFT_57805 PE=4 SV=1 +--KYPLSPPSLEELADNLQAPLAANYEHSSVSIVQCPDLRQAPFHLASEGLSGNEKIADIGGQGHLFPRPLLDRIYTMDKIAEAMDmSP-skGSLIGAGAGPFHRVGRNCELSPNISWKqgYE--NVDNKTCF---aqiSPNT-----gDVSIKKSPSLECALMANLYGSESEPGPVIKITARKRRGQeRSFTECIRKALVAAFGDlKTISLGGAFLIKTGKARYHVMP-DFPPDNelpFKDSRQLn-DWLTYHDFDGPIVCMTVLHSSDPgkAMGLRMEHTHGYSpqgg--DCGGHYHYDVdg-DENIEYEGYFNTAKAIYRIDMPSVRLERDLH +>tr|A0A1L7WYC4|A0A1L7WYC4_9HELO Uncharacterized protein OS=Phialocephala subalpina GN=PAC_07660 PE=4 SV=1 +--KHALDPPPLVELASVISKGLQANYKSSTVSIIPCPDLTASPFHLAAPGLSGHESIADIGGPPFLHPLPDFSKKYSLPDILSHCGdGEk-ggRFAIGAGAGPFHVVGQNSELAPNISVDgD--GEVNNLTKY---akiGKNGE----VISGPVPeGSTDCCLMANLFISSGLPGNVLKITAKSELApnisvdgdgEvNNLTKYA------KIGKngEVIS-G---PVPEGSTDCCLMA-NlfissgLPGNVL-KITAKKTWS-----------------NGCdsstWLGLRMEHTHCFAngkgKDGKGGHYHGDTedTKDEVEYEGYFNIARIIYRIDRPGGGHE---- +>tr|A0A1S3CZ75|A0A1S3CZ75_DIACI ester hydrolase C11orf54 homolog OS=Diaphorina citri GN=LOC103507401 PE=4 SV=1 +--RRDLFVPPVDDVISVLNQGLGKYFKEVSVSFTECPNLTSHPFNLTSAGLSGSPSLVEYGGASFLEPIANKSKIYDLKDLVNVTQtKP-TFAVGAGAGSWRFAGTNCEERRQTMLFsaTTTakTETLTKLAL---kkepvyigvDDTKEEATVagle--QGYVVcpSEKRFLLLFTFLKKNHigeivawhvLLLQVIKIKVQTRIGKEDFVTSVRNVL-AaHYKDq-PVGLGGVILIENAPAKHHVMP-DFSTTPLETKDQLNEWLVFKDLTPPLISVGTVISADVVSfDIKAKS------------------------------------------------- +>tr|A0A1V9XJ15|A0A1V9XJ15_9ACAR Ester hydrolase C11orf54-like OS=Tropilaelaps mercedesae GN=BIW11_09664 PE=4 SV=1 +--IHEYHVPPLENVAKVLQEGLQKSFTEVSVTVEDCPDLKKAPFHLAAEGLSGLPRICDIGGVPYLIPLAQPEKRYNYEEVASLAGVPDGFFVGAGAGPCHIIGTNSELMPNIKCSgGSGSLTRNETHYARICE-DGKSHLmEKVPNG--TADFCLMGNVFLSQGKPGKALRLRLKRRTGSDNLTTAIRKILLETFGPdKPVGLGGVFLISKGKAKLHIMP-AFSKTALTSDEDVDKWLHYFEFRAPLICLSVMSSCDPGWDLRIDHTHCFSTHGAGGHYHCDTTPDEVEYECWFNVAEKLVRVDQPKETHQIGRD +>tr|A0A1W2WJF0|A0A1W2WJF0_CIOIN ester hydrolase C11orf54 homolog OS=Ciona intestinalis GN=LOC100177644 PE=4 SV=1 +--NVALHVPSMEELAEVVGVGLKKNYKEWSCSVVDCPDLSKAPFGLASNGICGRTRLVDVGGVPNLVPVSQyMEKVYNLQDISERVGTPGCFILGAGAGSKHVVGCNCELMPNFRCEgG-ERERVNLCHVARVKS-DGGYLLqnyENDHGS--SSEFSLLANLFCSDGKQGKVLEVRGKCRIGEKDLVGCMRGALKEHFGPnRPIGMGGTFLVNKGKIKIHVMP-DFSETPLTSDNDVNNWLKFYEVTSPFMCLSTFITEDCGLDLRVEHTHGYNaNSGVGGHYHYDVTPDEVEYIGYFTPAEFIYRVDRPSTTHNIGRD +>tr|A0A1W5A4D0|A0A1W5A4D0_9TELE ester hydrolase C11orf54 homolog isoform X1 OS=Scleropages formosus GN=cunh11orf54 PE=4 SV=1 +--KYELDVPPLQELCDVLHNGLKNNFADAQVRVVECPDLSQAPFHFPANGLCGSPRIMDVGGVPYLIPLVQLDKVYNMNTVAKEV----------elpgafilgaGAASSRTLGMNAELMPLVVTEieGR--SALNG------syfsyiNPADGTCLQe---KYSDrfDDCDFGLLANLYACEGKAGQVLEVKASRRTGEDSFVTCLRKTLEKFYSDk-CLGLGGTFIMQNGEAKIHIMPQEFSTCPLSSDEEVNKWLKHYTVRAPLICQSVLVSRDPGLDLRLEHTHCFSHHGEGGHYYIDTTPDVVVYLGYFLPAEFIYRIDRPSNTHRIGRD +>tr|A0A1D1VWM8|A0A1D1VWM8_RAMVA Uncharacterized protein OS=Ramazzottius varieornatus GN=RvY_15923 PE=4 SV=1 +--RYSLEVPSLEDLVDVFRIALEANFRNVAVRIVDCPDLTEPPYGMAAKGISKSTKISDVGGVRYLTPLPQLDHKYDLQTIAKESElSPPYFIMGAGCGPYQDVGCNCELMANVAVSsAGV------------vknesriaklDK-DGKCQI--ERLQ--TTNLAILGNFFLSAGEPGKVVEIRAEGRTGSENFVSILRQAVRARYQEKPVGIGGVFLVEKGSLNIHVMP-DFSKAPLETEGTVDQWLKYFTQPAPMVFMSVFVSEDPGWDLRCEHTHGYGvpdaegss-QNRGGHYHYDTTPDEVEYVGYFGCAETLYRIDRPPSSS----- +>tr|A0A1W0WDZ8|A0A1W0WDZ8_HYPDU Ester hydrolase C11orf54-like protein OS=Hypsibius dujardini GN=BV898_12290 PE=4 SV=1 +--KLELRTVGLDDIATVFQAALEANFTEVSVAVVDCPDLTLPPYRMAARGLSGSTKIADVGGVRYLTPTPQLDHIYSLRDVGKLTGsNDGCFVIGAGAGPFQETGCNCELMADAFISteADH------------skivsqtaklNK-DGKCVV--TSLT--TPSLAILGNFFVSKGEPGKVIEIRAKRRTGADDLIACLRKSLARQFGGTPVGVGGVFLVQKGRVNIHVMP-DFSKTPLATQDEVDKWLQYFEFPAPMIFQSVFVSEDPGLDLRLEHSHGHSlldekgecEHSHGGHYHYDTTPDEVEYVGFFNAAEALYRIDRPKGQ------ +>tr|A0A1V8UU19|A0A1V8UU19_9PEZI Uncharacterized protein OS=Rachicladosporium sp. CCFEE 5018 GN=B0A51_04439 PE=4 SV=1 +--KYTLTPPPLEDLATRLQSALAKNYGHSSVTVSQCPDLRLPPFYLATQGLSSNECIADVGGQANLFPKPRLECKYSLLEIAKAMEmGP-evGSLIGAGAGPFHVVGQNCELAPTLSWKgsFE--NIENRTYV---akiAKDS-----gEAIVSKYPSTDCALMVNLFGSSGLPGPVLKITARGRQGSeGSFPKCIRTALHEAYGDsKPVSLGGVFLVKSGKARYHIMP-DFPS--kpFGSRDDVe-DWLAYHTFAAPMVCLTVMHSADPg-LGLRMEHTHCFApnrr--NAGGHYHNDVesEDgEEIEYEAYFNTAKAIYRIDAPS-------- +>tr|A0A1V6T965|A0A1V6T965_9EURO Uncharacterized protein OS=Penicillium steckii GN=PENSTE_c010G10284 PE=4 SV=1 +--IYPRDPPSLLDLAEVIQRSLQFNFTEASVGVEQCPDLREEPFGLAAPGISGNPCIADIGGQPNLFPTPNFNAQYSLLELATDMQiSP-fgGSLIGAGAAPFQDIGHNAELAPNISWKpaGNHqkpdfsdhstLEIRNNTRI---ievNDE------kLPSCDGTSSTNCALMANIYGSNGQPGLVLKVKARGRIGDq-NFTNCIRHGLRDTYGDsRPISLGGVFLLKKGKAKFHVMP-DFPSKKdlpFRDREQLeKEWLTYHVFKAPIVCLTVFHSADPeLLDLRMEHTHCFDaegd--KKGGHYHYDIqedd--FEVEYEAYLHPASTIYRIDRPAS------- +>tr|A0A210QIS0|A0A210QIS0_MIZYE Ester hydrolase C11orf54-like OS=Mizuhopecten yessoensis GN=KP79_PYT16172 PE=4 SV=1 +--KASTHVPSLDEVAKALSGGLSQNFANVSTSVVDCPDLTKKPFMLVSEGLGGNPRLADVGGPGFLTPTPQTDKKFTFAQIAKLAELPGAFMIGAGAGPCQHVGCNSELMNNILLDsNG-GVVRNNAHIAKVnPE-NNACVLe--K-LS--CPEFNLMGNFLISEGKSGKVLEVKAGKRTGEENFVSCMRKTLKSYYGDKIVALGGVFLIEKGKANLHIMP-DFAKEPLHTNEEVKNWLKFYDMSAPLVCVGELVSHDPGMDLRVEHFHCFSEHGEGGHYHWDTTPEDVQYRGYFVLADYIYRVDQPPNITDLAR- +>tr|A0A1Y2LVB8|A0A1Y2LVB8_EPING Uncharacterized protein OS=Epicoccum nigrum GN=B5807_06372 PE=4 SV=1 +--KLDLHPIPLQELSDAIKTGLAHQFESTSVSVEQCPDLQQTPYNLAFAGLCGSPRIADVGGQPNLAPTPDFSKKYDLLDIARLMELPKeqGALLGAAAGPFHVVGTNSELMPILQWNgA---EVVNQTHFAKVKD-DGSALC--EKLA--SHDCALMANLFGCEGLPGDVLHITASSRTGSLNFTEAIRRSLEDAYGQKTISLGGVFLISKGKAKLHIMP-DFSFVPLITDEQKQKWLKFYETEAPLVCLSVLHSHDPGLDLRIEHTHCFSDHGEGGHYHYDTTPKDVQYEAWFNVAKILYRIDRP--------- +>tr|A0A1Y1K938|A0A1Y1K938_PHOPY Uncharacterized protein OS=Photinus pyralis PE=4 SV=1 +--CKPLHVPPLEEIADVLNKGLKKHFQDVKVEVVNCPDLTQMPFTLANKGLNGNTHMMDVGGPPYLVPFVQYDKVYDLCDIPDVVKm---ksAFIIGAGAGPHPYATVNCEAIMNINIEnS---LVKQQTRI---vkvNQTdG-TPVQe-QLPTT--ETRFALLGNFFICEGKPGQVLQVHVKKRVGCMDFIASIRGVLADHY-GnRILGLGGTFLLREGKAKQHVMP-HFSETAINSDDEINQWLKFYEMSAPLIANGTLITGDYDLDLRVQHFHSFSYHGEGGHYHIDTTPDTVEYLGYFNLAQDIYRVDKPEHTHKVGRD +>tr|A0A232ENF9|A0A232ENF9_9HYME Uncharacterized protein OS=Trichomalopsis sarcophagae GN=TSAR_003978 PE=4 SV=1 +--PQINHNAIFMFVIAVFLKALKENFEEAEVQVVDCPDLTEEPFTLAAPGLGGRLNIVEVGGPSFLLPSVQKDKVYDVQPLLKEIKyG--drAFVAGAGAGPWPYKNSNCEMMMNVMINsS---KLKNQTRI---ssvNTEdE-TCVLe-TLKGN--ETRFALLANLFLCEGITGKVLKVHAKKRIGKKDFIATMQQALAEHY-TdKLVGLGGSFVMKEGKAKQHIMP-DFSEKPLNSVKELDDWLHYYDMSAPLIAVGTFVSAETDLDLRVQHFHSFSHHGEGGHYHIDTTPDTVEYLGYFNLGEVLYRVDKPPVALQFGKD +>tr|E9IBH5|E9IBH5_SOLIN Uncharacterized protein (Fragment) OS=Solenopsis invicta GN=SINV_12208 PE=4 SV=1 +--SRALHQPPLDELMNVLAGGLTANFEEATVEMADCPNFSGRPYYFFKEGLCGNPIILEVGSPSYLLPTVQRDKYYDIKSLLQQLNyNH-dTLIIGAGAGAWPLRDSNCELIMKLNLKlnDN-FQVRNGTHY---afvDKNNQGCKLe-RLAENDNITTFALLANLYVCEGKPGKVIKVRAKKRTGKLDFIACMQKALEKHY-EnKLVGLGGMFEMKNGKVKQHIMP-DFSDTPLTTEADLNNWLRFYDMETPLIAVGTFVSAETDLDLRVQHFHSAFdkDPGLGGHYHIDTTPDTIEYEGYFNVATTLYRVDQPPNKVQFGKD +>tr|J9K119|J9K119_ACYPI Uncharacterized protein OS=Acyrthosiphon pisum GN=LOC100165490 PE=4 SV=1 +--RIDLNVPTLDRIIEALLPELSNNFETVSVDAVQCPNLTCSPFNLAAEGLNGDEMVIDIGSPSFLLPLVNLNKVYDIRDFAKVTGt---dpLFVIGAGAGPWPHVGVNCEFIGNVRLTsdDSV-NNNNSSHL---ykv-DPqTGSQVHh-RLPQD--ETRFALLANFYTSRGMTGEVLKIVCETRNGPLDFVTSIRKALAKYF-GdKPVGLGGVILIETSKVKVHVMP-DFSKIPLDSEADLNNWLKFFEVSTPLVALGYLVSHD-pGLDLRPQHFHLFGNHGEGGHYHHDTEPTTVKYTAYLNVAKKLIRVDQPETALLFGKD +>tr|A0A0A1WF70|A0A0A1WF70_ZEUCU Ester hydrolase C11orf54 OS=Zeugodacus cucurbitae GN=C11orf54 PE=4 SV=1 +--EKPLYVPPLHELKEIIQSALAQNFENVTVEVGDCPDLTDPFYGLVSSGLGGSPLLLEIGGPPFLLPLVQRSKVYNVKEIAQKALpG-kGkILAIGAGAGPFPLRNSNCEGIFNMAIDeEG--NLKNGSYT---akvHGAEELCVLe-RIPDS--DPRCALLLNLFISRGAPGPVVKVKCSKRTGEQNFVECIRKGLESHYKEQCVGMGGIFVLKKGAAHQHVMR-DFSKTPLNTEEELNDWLKFYNMPAQLNALGTLITHENDLDLRLQHFHSFSKSNWGGHYHHDTTPEVAEYEAYLNVAERVVRVDRPLETHKVGRD +>tr|A0A226EZ34|A0A226EZ34_FOLCA Uncharacterized protein OS=Folsomia candida GN=Fcan01_03965 PE=4 SV=1 +--EFVLPSVDIEDICKALNENLKAYFQNVDVNVVDCPNLAEPPYNLATNGIGGYCVIADIGGVPYLIPLVQRDKVYDLRTLIPECVgADkfPegWYISGAGAGPFKSQGSNCELIVNMYLSpdD--KVVNR-SKV---alTSSQNETD-LTVKTLSdTETDSSLLVNVLVSSGaGKVLDIKVSHKLDPA-TNFTTILRDCLNKKF--tasTPVGLGGLFTVDRAPTKIHVMR-DFSTKPLLTDNDVEEWLKFFRVEPPFMSQSILVSTDPGLDLRVEHSHGWTthsgpa---QAGHYHYD-tAPQDVQYHGIYAVASKIVRIDRPKETHNIGRD +>tr|A0A1Z5SX21|A0A1Z5SX21_HORWE Uncharacterized protein OS=Hortaea werneckii EXF-2000 GN=BTJ68_11441 PE=4 SV=1 +--THPLSPPTLEEICSTIRPALRANYKESTIDIVTCPDLTAPPFHLASQGLSGNESIADIGGQAHLFPRPLKEKQYSLIDCAKSMGmSQ-qrGLLMGAGAAPWHVIGQNAELAPNVSWEgsMDEeg-KVRNQTFV---trvESQG-----gHVRCERLPSMEFALMMNLYGCEGITGDVLRVTAKGRRGEqGSFTECLRQALHAEYGEeRQ------------------------------------------FSAPMVCLSVLHSADPeKLGLRMEHTHCFStdk--DEGGHYHHEIlpdgSDeEEIEYEAYFNTAKLLYRIDMPS-------- +>tr|C7ZLH7|C7ZLH7_NECH7 Uncharacterized protein OS=Nectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) GN=NECHADRAFT_88680 PE=4 SV +--QLRLSPPFLEDIAQTLAKALPSNYITSSATV---TDLRQAPFKVTGEGLTGSETAADIGGQVDLLPQPYLHKTYSLIETAKLMGlSP-gkGAIIGAGAGPFLVDGTNSELAHHLSWGngFD--SVTNLTRA---aqlRKEG-----salPVCCPLSGSTDSGLMMNLYGSKGLPGPVIKPSARGRQGDvSSCADFIRQSLAKAYGVdLQVSLRSVFIIKSGKAKFHVIP-PFPKvdPPpfkFRNQEHLd-GWLSYHTFGGPMIRLAVLHCGDPeKIGIRLEHTHCYSner--GEGAHYHYDLqdsp-EnEEVEYERYFNTIKTFHQINYARTD------ +>tr|A0A0P4YAU6|A0A0P4YAU6_9CRUS Ester hydrolase (Fragment) OS=Daphnia magna PE=4 SV=1 +-ENCQLHVPPLSELADVLRQGLESHFAHVQVEVVDCPDLSSSPFHLAAPGLGGEPCLVDLGGVPYLVPTVQRDRTYDLADLPGLMNVKDGtiLMIGAGAGPWQHLNTNCEMMTNLSLTLEEgkSNIVNGTRLATVD-PAGQRMLHVVPPE--QTRCSLLNNLLISRGQPStPVLRIRCQKRTGPNNFVTCMRNTVAQHYGDKPVGIGGVFMLDNGQARLHIMP-DFSPCPLQTDADVNNWLHFYNATGPLINLSVFISHDPVLFYFMCFFfvlfHCSMtVRYIALLIKSSINPQIQVLGAY-----SCWTMARPGSIYS---- +>tr|A0A0G4FHT6|A0A0G4FHT6_9ALVE Uncharacterized protein OS=Chromera velia CCMP2878 GN=Cvel_17070 PE=4 SV=1 +-EVQSLNVPSLTEVKEVLSRSLPAFFEEVEVEVTPCPDLRESPYLSSFQGLSspGDGNvILDVGGVdnllpr------PNKKKLYDLSDLVRQAveklGLTSHptCLVGAGAGPCHVYGMNSELICNTCITGSStsKVal-------MIPQEETGKEKHEVK--DDVSNKSSVLLNVMLTEGKPGEVLRIRLRGRAGkDergKDVPQCIADCLKAHYGEsRPVSLGGLLVLKKGRARLHCMP-DFSKEPIRTPEGVDEWLRWMEGEAPMRFMFVATSADPGMDLRLVHThgwge----agGRRYGGHYHNDTTPEAVEYEMVCMTAGAIARLDRVTQTPN---- +>tr|E9FYW1|E9FYW1_DAPPU Putative uncharacterized protein OS=Daphnia pulex GN=DAPPUDRAFT_43127 PE=4 SV=1 +-ESCQLHVPPLDELAHVLRQGLALHFAFVQVDVVDCPDLSQSPFHLTAPGLGGDPSLVDLGGVPYLVPTVHRDRIYDLADLPAAMNVKDGtvSMIGAGAGPWQHLETNCEMMTNLSLSLEAgkSSslvVDNGTRLATVD-PSGRRILHVVPPK--QTRCSLLNNLLVSRGLPRtPVLRIRCQKRTGPDNFVTCMRNTVRQRYGHQPVGMGGVFMLENGQARLHIMP-DFSPCPLQTDADVNNWLHFYNATGPLINLSVFISHDPGLDLRVEHTHCFSt-HGEGGHYHEDVSPETVVYEGYFTPAERLFRIDRPSQTHG---- +>tr|A0A1D2MLD3|A0A1D2MLD3_ORCCI Ester hydrolase C11orf54 (Fragment) OS=Orchesella cincta GN=Ocin01_12942 PE=4 SV=1 +-DEFQLEKLELETIQNALNKNLPKFFEKVSVSVSDCPDLTQQPYNLATEGIGGKGSvLIDIGGPpylipl------VNREKVYDLAKIIPEHvgkeDYPDGwYASGAGAGPWPSQGSNCEMVINLKLDKDGgvVSnk----SKVALTS-SGAEEDLTVKELGNEESRCALLANLLVSGGKG-KIIEIKCTKRIDkSSNFTAAIRQALKEEFGEeKPVGLGGLFTVTLSDTKIHVMR-DFSNTPLESDDDVNNWLKFFHIKPPMLFQSVLVSSDPGLDLRIEHAhgw-NLNgERSEAGHYHYDDMPDTVEYHGIYAVAQKIIRIDRPQETHQ---- +>tr|A0A1I8J432|A0A1I8J432_9PLAT Uncharacterized protein OS=Macrostomum lignano PE=4 SV=1 +-RRFRLHRPDLVAVADCLDRACRDAFEDASVELiDSCPDLSEPPFCLASRGICggGGensGPvLSIAGGVpyllptp------QVEQRRYDLRNLLKATGHPDGLIIGAGAASSTRFGRNAELVANLGPLGNGcrVAsl-------RADGEDDGTENLANCRLsRPDFAEAGLMVDSLCSSGQTDgPVFRLRASRWRPeTatpdwsaaktrGRLAELLQRALAKEfSGCkLPVGLGGVFRLSGAAARMHVMP-DFSPTPLTCSAEVNSWLRFFNMPPPIVCCGVLISHDPHsWGLRLEHYhgwnp----sSEQCGGHYHYDASPDTAEYLGYFSLATSLLRMDPPGGVDS---- +>tr|A0A1X7V9X8|A0A1X7V9X8_AMPQE Uncharacterized protein OS=Amphimedon queenslandica PE=4 SV=1 +-EKRQLHTPDLSHVAQVIESGLKENFKEASVNVVDCPDLTSSPWQLAAPGLGGAPRLLDVGGVpylmpli-------QREKVYDLAQVASLAGLPNGFILGAGAGSYRVAGVNCEMMANIKFSDPDsgAPhnigsysakv---------ST-EDGSAIIEKFP----YTEAGPLANLLLCEGTPGaPVLEIKARKRVGEENFVTCMRKSLAAYFGEGPVGLGGVFMIKKGKAKLHIMP-DFSQTPLTTNEGVNKWLQFYNMSSPLTCLSVFISCDPGLDLRVEHTHCFSSHGDGGHYHYDVTPQEVEYHGYYVIAEEIVRIDRPIKTHQ---- +>tr|A0A1U7UAF8|A0A1U7UAF8_TARSY ester hydrolase C11orf54 homolog isoform X2 OS=Tarsius syrichta GN=LOC103266437 PE=4 SV=1 +-SEFSFHVPSLEELAGVLQKGLQDNFAEVQVSVVDCPDLTKEPFTFPVNGICGKTRIAEVGGVpyllpl------VNQKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPVIQTESEHRPpvngsyf-------ARVNPEDGGCLLEKYSEKYHDFGCALLANLFASEGQAGKVIEVKAKRRTGQLNFVTCMRQTLEKHYGDKPVGMGGTFVIQKGKVKSHIMPAEFSSCPLNSDEEMNKWLHFYEMKAPLVCLPVFVSRDPTLPPVPTDYkrkaaRLFLpGRGQIN-LKEELSskPGTV-AQAY-----NLGT------------- +>tr|A0A1V8SQ10|A0A1V8SQ10_9PEZI Uncharacterized protein OS=Rachicladosporium antarcticum GN=B0A48_13383 PE=4 SV=1 +-SKHTLKPPPLEDIATKLQSALANNYRHSSVTATECPDLRHAPFHLATQGLSGNECIADVGGQanlfpt------PRLECKYSLLDVAKAMEMDPEggSLVGAGAGPFHVVGQNCELAPNLSWKGSFdnVE--NRTYVAKIAKDSGEAMVSRC---S-STDCALMVNLFGSSGMPGPVLKITARGRKGkEGSLPECIRTALHAAYGDsQPVSLGGVFLVKSGKARYHIMP-DFPSAPFENRDDVEKWLTYHTFAAPTICLTVMHSADPGLGLRMEHTHCFAsdGQNAGGHYHNDVEsdLSD---------------------------- +>tr|T1L1G0|T1L1G0_TETUR Uncharacterized protein OS=Tetranychus urticae GN=107369328 PE=4 SV=1 +-KTCDLEPISLKELSTTLQDHLSKIYGHVKVSVVNCPDLSKEPFNLAGSYLGgkTA--IADLGGIpylvpvg------YAAAPIYPLIHLAKKMGFQDAHLMGAACVPFQITGSIADFMPNISYSTDEqtGKttVNHGSYYSEMVDDKKHIMR-----HLASDCVTVLANVFISENKPSKEIKIVASKRVDkRgESLTIAIRDILRIAYPEKAISMGGMFLARKGKINIHVMPNDFSKTPCDTEEKVNEWLKYFEASAPIVGLVTLHSKDPGFNFRDEHThc----iGKGEGGHYHHDTTPDTIEYEAYLNIAQKIVRIDQPALNNE---- +>tr|R7V6P0|R7V6P0_CAPTE Uncharacterized protein OS=Capitella teleta GN=CAPTEDRAFT_151463 PE=4 SV=1 +---------------------------------------------------SGE---LPVQKAPLHCPPLdeVAKEIFDLSKVPEWTELPDAFMLGAGAGPRHVEGINCEMMTNLQVTPDGV--NNQSYIAKVGTEDNKYIVKKV---DNTTDCCLLMNLFVCEGKPSKVLEVKASKRTGPQNYMLCLRDVLAKHYGTQPVGLGGTFLMRKGSAKIHIMPD-YSDIPLESDAAVDAWLKFYEMKAPMIFMGYVISHDPDMDLRVEHFHGFSQHGDGGHYHYDTTPDEVEYVGYFNLGESMYRVDRPSVTHGIGRD +>tr|A0A095BUD1|A0A095BUD1_SCHHA Ester hydrolase C11orf54-like protein OS=Schistosoma haematobium GN=MS3_00610 PE=4 SV=1 +---------------------------------------------------SGKAIICDVGSFDYLLPVPkkdrvcivlsdLLAKHYDLLDVFRSAGVAAGAVIGAGAGPFFLTGSNSEMVINISSESG--VVKNGSLFGLYDKENNKPLLTK----ADNTKFALLGQMFMCEGKPGPVIELNVSGRIQDGKFDAMIREALHVKYGHlnNAVGLGGVIVQEKGKSLYHVLPE-FSQEPIDSGEKLRNWIKMFEMESPVISVGIAVSHDPHhLGLRLEHFHCFNQNqTNCGHCHFDTYGPTVSYRCYFSIANHLLRIDQPSKSL----- +>tr|A0A0B1S6J6|A0A0B1S6J6_OESDE Uncharacterized protein OS=Oesophagostomum dentatum GN=OESDEN_19781 PE=4 SV=1 +---------------------------------------------------GRNMVIAEVGGLGNLYPG-fHKEKHYD----------------------------------------LK-VA---SKITTLAENKSVP---FETKTINSTKFTLTGNFIVTAEPGPaEVVHIKCSERTGKLCFPDTLRESLEQRYGKECVVLGGLFRLLRGKARVHIAPE-FPEKPWKSMDEVEHWYQPFVVSAPLLCASVMHSYD-PgFKLRMQHTHCISDHNDAGHFENDATPEEAEYEGWFTAAEKMYRIDEI--------- +>tr|A0A0B1TGM0|A0A0B1TGM0_OESDE Uncharacterized protein OS=Oesophagostomum dentatum GN=OESDEN_04825 PE=4 SV=1 +---------------------------------------------------DRNLTIAEVGGPGNLFPT-iHKEKEFDLKKICEECHAPSAFVFGPGAGPWQVVGKNCEMVADANFAIPK-VA---TKVAFINDGQSTT---YKQSTIDSSKFSLMANLAVSGEPGPgEVVHCKCSVRVGKENFPEAIRKGLAEHYGEklfysRCVSLGGIFLLREGEAKLHVMPD-FPGCPFKSTEEIDKWLRFFTMKAPLVCASVFHSYD-PgHKLRMEHTHCYSEHGDAGHYHYDTTPETVVYEGWFAAAEKIYRIDEV--------- +>tr|A0A0N4VEE8|A0A0N4VEE8_ENTVE Uncharacterized protein OS=Enterobius vermicularis PE=4 SV=1 +---------------------------------------------------GSSLRIAEVGGVSNLFPT-pQKNKYYNLKELAETCELSDGFIFGPGGGPRHIIGTNCEMVADACFEKGKEKvA---VKMGVVTTKVPQG---HEMITTEKPEFCLMANLGVCKGSIPtSVLKIKARKRLGDLNFPEAVRRAIATHYKDQLVSCAGIFLLKGSKARIHVMPD-FPSGSFASAEEMEKWLKIFEIDGPIVAASVIHSKSVDnYKLRLEHTHCYNKH-EAGHYYCDTDPESVEYEGYFAVASAVYRIDLA--------- +>tr|T1GCC9|T1GCC9_MEGSC Uncharacterized protein OS=Megaselia scalaris PE=4 SV=1 +---------------------------------------------------------MEVGGPPYLLPLVdr--TKLYDIKTLSqRALGNKEIFAIGAGAGPFPLRGTNCEGIYNLKISADGKV-TNKSYSAKVHGPEENCVLEQIP-D-TETKFGLLLNLFLSEGKSGKVLKVHCKKRTGPLNFIESIRYALLDFYKEKCVGLGGMFMIKSGKAHQHVMRD-FSKTPIYSEEELNQWLKFYEMPAQLNGVGTLITHENDLDLRLQHFHSFSSSNWGGHYHYDTTPDTVEYEGYFNVGEKVIRVDKPVNTHKFGRD +>tr|A0A0C2CUP1|A0A0C2CUP1_9BILA Uncharacterized protein OS=Ancylostoma duodenale GN=ANCDUO_09117 PE=4 SV=1 +---------------------------------------------------GRKLVIAEVGGPGNLFPK-iRKEKEFDLQDVCKECHAPSSFVFGPGAGPWPVVGRNCEMVADANFASSK-VA---TKIASLVEGHTTP---YKMSIIDSPKFSLMANLAVSGEPGPaEVVHCKCSVRVGKDNFPETIRKGLAKHYGKMCVSLGGIFLMREGEAKLHVMPD-FPGCPFKAREEVDKWLRFFTMKAPLVCASVFHSYD-PgHNLRLEHTHCYSEHGDAGHYHYDTTPDTVVYEGWFTAAEKIYRIDEI--------- +>tr|W2T636|W2T636_NECAM Uncharacterized protein OS=Necator americanus GN=NECAME_11122 PE=4 SV=1 +---------------------------------------------------GRKLVIAEVGGPGNLFPT-lHKEKEFDLHQICKDCNAPSSFVFGPGAGPWQVVGKNCEMVADANFASSK-IA---TKVASIEEGQSKP---YKVDVINSPKFSLMANLAVSGEPGPaEVVHVKCSVRSGQDNFPETIRKGLAKHYGEKCVSLCGIFLLREGEAKLHVMPD-FPGCPFKAEEGVNKWLRFFTMKAPLVCASVFHSYD-PgHKFRMEHTHCYSDHGDGGHYHYDTTPDTVVYEGCMETSPSPSNPP----------- +>tr|A0A0B1TDA4|A0A0B1TDA4_OESDE Uncharacterized protein OS=Oesophagostomum dentatum GN=OESDEN_04823 PE=4 SV=1 +---------------------------------------------------GGRTEmesarSWQEGSPQNLVEGSslqeagifhcepfnFCLLSDTVQKICEECHAPSAFVFGPGAGPWQVVGKNCEMVADANFATPK-VA---TKVAFINDGQPSA---YKQSTIDSSKFSLMANLAVSGEPGPgEVGK--------------------------sRCVSLGGIFLLREGEAKLHVMPD-FPGCPFKSTEEIDKWLRFFTMKAPLVCASVFHSYD-PgHKLRMEHTHCYSEHGDAGHYHYDTTPETVVYEGWFAAAEKIYRIDEV--------- +>tr|G7YEP6|G7YEP6_CLOSI Ester hydrolase C11orf54 homolog OS=Clonorchis sinensis GN=CLF_106094 PE=4 SV=1 +------------------------------------------------------MTECED----------lvnailatlesRSLLRYDLLDAFSLSHIGSGLIMGAAAGPHFVAGINSELVANLSAIDGK-VLQNGSYCGSYDAKNNLPVSTL----SETSLFAMVGQMFLCEGKRGKVIQLTVSGRTREGKFDALLREALASKYAAldRPVGVGGVVVQETGKCLFHVLPE-FCAEPLDTPEKLKQWLKFFEMEAPVVAVGTALSHDPQkWKIRLEHFHCFNNDrTKSGHCHFDCDGPTASYTAYLVPGKRLLRVDPPN-------- +>tr|A0A182ZLD2|A0A182ZLD2_BIOGL Uncharacterized protein OS=Biomphalaria glabrata PE=4 SV=1 +----------------------------------------------------------------------------------------------AGAGPNHKVGINCELICNVKVGEG--A-INKTRIAKIDETTGSYVLEEET-S-------AIVHALKFHLKKNQVLQIKAKNRIGIENFVSCIHKTLTAHYGDKAVGLGGTFLLQTGKANIHVMPD-FLDEPLITDEQTNAWLKFFEMDAPLIHVGEIVSADPQkLHLRQEHFHCFSHHGQGGHYHYDTTPDDAAYLAYFSVAEFVYRIDLPETRNFIF-- +>tr|A0A1L1SSF8|A0A1L1SSF8_MOUSE Protein 4931406C07Rik OS=Mus musculus GN=4931406C07Rik PE=4 SV=1 +---------------------------------------------------CGQTRIAEVGGVPYLLPLVNKKKVYDLNEIAKVIKLPGAFILGAGAGPFQTLGFNSEFMPIVQ--TASEHnqPVNGSYFAHKNPADGACLLEKYSQKYHDFGCALLANLFASEGQPGKVIEVQAKRRTGELNFVSCMRQTLEEHYGDKPVGMGGTFIVQKGKVKAHIMPAEFSSCPLNSDEAVNKWLHFYEMKAPLVCLPVFVSKDPGLDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAQFLYRIDQPKETHAFGRD +>tr|A0A0D2YJX9|A0A0D2YJX9_FUSO4 Uncharacterized protein OS=Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936) PE=4 SV=1 +-----------------------------------------------------------------------MDCVWSMTELAeaMDMDPAKGGLLGAGAGPHPVIGQNCELAPNIGWQGSFENVKNESRYAKIDKETSAVHVDK----SPSLDCALMINLFGSSGNPGPVIKITARKRTGSeRSFAECIRKGLRLAYGDeQTVSLGGLFLVKKGKAKYHIMPD-FPTekdLPFNNRKDVDSWLTFHDFDAPMLCLSVLHSADREgrMGLRIEHTHCYAADgkNAGGHYHYDLddTEDDIEYEAYFNTAKMIYRLDRPN-------- +>tr|A0A1L8H894|A0A1L8H894_XENLA Uncharacterized protein (Fragment) OS=Xenopus laevis GN=XELAEV_18015384mg PE=4 SV=1 +---------------------------------------------------VIETECPDLSKEPF------EFPVYNVNSVARKIGLPGAYILGAGATSHKSLGMNADKKTRLAEQAESAGtvAVNKSYVASVNPGVGSCLLEKYRDRNNDNNFGLLYNLYACEGKTGK------------------------------------------------------SACQLNSDEDVNGWLKFYEMTAPLICQLVFVSHDPGYDLCLEHTHCYSHHVEGGHYHYDTTPNTLEYLGYFHPAEFLYRIDKPSDTHMVGRD +>tr|L8YBB9|L8YBB9_TUPCH Uncharacterized protein OS=Tupaia chinensis GN=TREES_T100004622 PE=4 SV=1 +---------------AVLQKGLKTNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLINRE---------------------------------------------------------------------------------------------KVIEVKAKRRTGQLNFVTCMRQTLGNHYGDKPVGMGGTFIVQKGKVKTHIM---------------------------------------GFDLRLEHTHFFSHHGEGGHYHYDTTPETVEYLGYFLPAELLYRIDQPKETHLIGRD +>tr|A0A0B2VAD5|A0A0B2VAD5_TOXCA Ester hydrolase C11orf54 OS=Toxocara canis GN=Tcan_18580 PE=4 SV=1 +--KLSLKVPPLEELSSILDPALRKNFGQISIDIVDCPNLREAPFSMTGAGIGNGLRIAEVGGIPNLYPRG-GKKIFNLKKVCETCEMPHAFVFGPGAGPFEAVGHSSELVANANFIE-HEYKVA-NKVSWVVPSGKG-----YTMSTiDSSDFEITANLAISDGCPGrKVLRIRAAKRNGEMNYPEAIQKALGAHYGDTLVSLAGLFVLQKGKVRMHVLP-DYPESPRKADEKKDDWlqyMRYFEMDAPIVFASVVHSNDvGGYKLRVEHTHGYSEHGDSGHYHIDTTPNTVEYEGYFSPANIVYRIDMV--------- +>tr|A0A0M3I6F9|A0A0M3I6F9_ASCLU Uncharacterized protein OS=Ascaris lumbricoides PE=4 SV=1 +--KIVLKTPPLEELSSILCAELKKNFVDVSVDIVDCPNLRAPPFRMSGAGIGNDLRIGEVGGIGNLFPSPKTDKFFNLKKICETCEMPKAFVFGPGAGPFHIVGNNCEMVADADFTTDHQNNVA-TKVSRVVPNGKG-----YEMSTiDNADFVLMANLAISDGFPAgKVLRVHAAKRNGEMNYPGAIRKALIGYYGNSLISLAGVFLVKKGKVRMHVMP-DFPGCPWETIEEMdKEWLKYFEMKAPLVCASVLHSNDiGGYKLRLEHTHCYSEHGDAGHYHYDTTPDEVEYEGYFAPAKFIYRVDML--------- +>tr|A0A0M3KCR7|A0A0M3KCR7_ANISI Uncharacterized protein OS=Anisakis simplex PE=4 SV=1 +--KINLVVPSLDELKSVLHDSMVKNYESVSIDIVECPNLRESPFRMTGSGIGNNLRIAEVGGIPNLYPHG-TKKIFNLKKVCETCELPEAFVFGPGAGPFDAIGHSSELVADANLIK-SQFKIA-NKVSWIVSSANG-----YTMSTtDSTDFEITANLAISDGCANrKI---CATKRIGELGYAESIQRAIESYYGRnhQLVSLAGLFLLHKGDVYMHILP-DYPVSPRKQDEKFfR------ESERKTTGXSVVHSHDnDGYKLRVEHTHGYNESNKsGGHYHIDTTPEIAQYEGYFAPAHCIYRIDKI--------- +>tr|E3N569|E3N569_CAERE Putative uncharacterized protein OS=Caenorhabditis remanei GN=CRE_19401 PE=4 SV=1 +--VIENHVPSLEELKEvrlvircsklqptqVFQKSLDANFETVQVDVVDCPNLSEPPFHQTSSGFGQNLKIAEVGGPGNLFPGFHTDHQFDIRTIGKVCEHPEASVFGPGAGPWPVVKKNCEMVADVNLKTG---KTA-TKIAeiy-----QEK-----YRQRTiEEPKFSLMANLALSDADKSaKVVHFKASVRTGEKNVTHCIRDGLQEHFGERPVSLAGQFIIHTGQAKLHVMP-HFPGCPFANNEEVDKWLNYFTMDAPLVCATVMHSYDPGHNLRLEHTHCYSEHGDAGHYHYDVTPATVAYEGWFAPAGKVYRIDEV--------- +>tr|H3G356|H3G356_PRIPA Uncharacterized protein OS=Pristionchus pacificus GN=WBGene00118571 PE=4 SV=1 +--RLETHVPSLEAIADAFRSKLPSNFETVTVDIVECPDLSSAPFNLTSPGFGKNLVIAEVGGPGNLFPTIHKEKAFDITKICSTCEQPRAFAFGPGAGPWPIVGVNCEMVADVNCADN---KVG-TRTAkieg------DS-----YKVEQiDSSTFSLMANLAVSEPQGGqRVVHIKAKRRTGKTNFPDSLRQSIVKAFDGKLVSLGGFFVLHSGRAKLHVMP-DFPGCFETEeevrltnephevnaFQIVSQWLRYFEMNAPLVCATVMHSNEgNGHKLRVEHTHCYSAHGDGGHYHYDTTPDEVEYEGWFAPASAVYRIDEI--------- +>tr|A0A183V321|A0A183V321_TOXCA Uncharacterized protein OS=Toxocara canis PE=4 SV=1 +--KIILNAPSLEELRPILENALKKNFEQVSVDIVECPNFKAPPFSMSGAGIGNDLRIGEIGGIGNLYPSPRTDKVFDLKEICVTCEIPEAFIFGPGAGPFHVVGHNCEMVADANFIE-RQNNVA-TKIAEITASGKG-----YRMSTiDKTGFALMANLAISDGRPNgKVLRIRATKRNGEMNYPESIRKALTAHYGETLVSLAGVFVLKKGKVHMHVMP-DFPGCPWKTHEQVNEWLKYFEMNAPLVCTSVLHSNDvGGHKLRLEHTHCFSEHGDAGHYHYDTTPNDVDYDGYFAPANVIYRIDMV--------- +>tr|A8XV43|A8XV43_CAEBR Protein CBG19223 OS=Caenorhabditis briggsae GN=CBG19223 PE=4 SV=1 +--VIENYVPSLEELKEVFQSSLKLNFETVEVDIVNCPDLSKSPFHQTSSGFGQNLRIAEVGGPGNLYPGFHINHQFDIKTIGKVCEHPEASVFGPGAGPWPVVRQNCEMVADVNLKTG---RVG-TRIAeidt---KNEKL-----YVQRTiDVPKFSLMANLALSDADKSsKVVHFKASGRTGQKNVTNCIRDGLQEHFGEKVVSLAGQFIIHSGQAKLHVMP-HFPGCPFENNEEVDKWLNYFTMSAPLVCSTVMHSYDPGHNLRLEHTHCYSDHGDAGHYHYDVTPDSVSYEGWFAPANRIYRIDEV--------- +>tr|Q3Y402|Q3Y402_CAEEL Uncharacterized protein OS=Caenorhabditis elegans GN=C24B5.4 PE=1 SV=2 +--VIDNHVPSLEELKMVFQTSLLSNFENVEVNIVDCPDLSKPPFNQKSSGFGHNLRIAEVGGPGNLYPGFHIDHQFDIPKIGKVCEHPEAAVFGPGAGPWPIVGQNCEMVADVNLKTG---EVG-TRIAeins---NSDKR-----YVQRIiDEPKFSLMANLALSDADKSsTVVHFKASVRKGEKNLTNCIRDGLQEHFGKKIVSLAGQFIIQTGKARLHVMP-DFPGCPFENNAEVDKWLNYFEMSAPLICATVMHSYDPGHNLRLEHTHCYSDHGDAGHYHYDVTPETVSYEGWFAPASKIYRIDEI--------- +>tr|A0A183FJK9|A0A183FJK9_HELBK Uncharacterized protein OS=Heligmosomoides bakeri PE=4 SV=1 +--VINTLKPSNNELRSVIETALWKNFKNVQVAVSNSPDLSKPPFRMTSNGFGKKLTIAEVGGMGNLFPVLRKE-EYDIREICSLCDKKSAFVFGPGACPKSVMGTTGELVADVNLSTN---KAR-CQSPsishgmaaravaskvttIVNDECLP-----YKTTAiDSTKFSLMANLAISEEPGPaEVVRATFLVA----------PPTVSRAHTCSCVSLAGIFLLLRGQASAHIVP-DFPTGNFKSIEEEEQWLRKFTLKAPLVCTSVFHSYDAGHRLRMVHTHCYSDHNDAGHFYTDITPESAVYEGWFTAAEQVYRIDKV--------- +>tr|A0A0D8Y0E7|A0A0D8Y0E7_DICVI Uncharacterized protein OS=Dictyocaulus viviparus GN=DICVIV_03527 PE=4 SV=1 +--IIETLKPSNRELRPIVETALKTNFKNVSVEVVSCPDLSIEPFSMTSTGFGRKLVIAEVGGIGNLFPIIHKEKEFDLQEICDSCQAASSFVFGPGAGPWKLVGKNCEMIADANFSIS---KVA-TKIVsisssdpPSY-----------TLSIlNSPKFSLMANLALSEPG---TGECTANVRFELEMIIflklyEEGLLNITEKSVVLCVSLAGIFLLREGEAKVHVMP-GFPGCSFNTKEEINKWLRFFTMKAPLVCASVVHSYDAGYKLRMEHTHCYSSHGDGGHYHYDTTPDTVVYEGWFTAAEKIFRIDEV--------- +>tr|U6NTY2|U6NTY2_HAECO Uncharacterized protein OS=Haemonchus contortus GN=HCOI_00414200 PE=4 SV=1 +--IINTLKPSNNELRSVIENALWKNYKNVQVTVDTSPDLSKPPFRMTANGFGKKLSIAEVGGMGNLLPILRKD-KLY------NTEKKSAFVFGPCASPASIVGATGEFIIDANFATS---KV------agkvtiQQKGHTSP-----YKMLIfDTPKFDLMANLAISEEQGPgEVVHVKCSERKGEDNL-pGCIRKELARHYGPSCVSLAGIFLLLQGKADVHIVP-DYPTDNFKSMDEVRKWFHMFNVKAPLVCATVFHSYDPGHNLRMEHTHCYSDHNDGGHYHTDTTPDTVAYEGWFTAAEKIYRVDQV--------- +>tr|A0A158PFA5|A0A158PFA5_ANGCS Uncharacterized protein OS=Angiostrongylus costaricensis PE=4 SV=1 +--LIETLKPSNSELLPIVESALKSNFKNVTVEVGPCPDLSAEPFSMTSSGFGQKLVIADVGGPGNLFPKIHKEKEFDL-KICKVCQSPFSFVFGPGAGPWKVVGRNCEMVADANLTTA---KVI-LSS-gyvdpLNRRYMLI-----FHYIIlNASRSL-----LFSLCR---LVHCKCSVRIGKDN--fpe-TIRKALAKHYGERCVSLAGIFLLREGEAKLHIMP-DFPGCQFSSSEEVDKWLQFFTMKAPLVCASVFHSYDPGHKLRMEHTHCYSSHGDAGHYYYDTTPDTVAYEGWFTAAEKIYRIDEI--------- +>tr|G0NTX6|G0NTX6_CAEBE Putative uncharacterized protein OS=Caenorhabditis brenneri GN=CAEBREN_29657 PE=4 SV=1 +--VIENYVPSLNELKEVFKSALTSNFETVEVDIVDCPDLSKSPFNQTSSGFGCNLRIAEVGGPGNLYPGFHIDHQFDISTIGKVCEHPEASVFGPGAGPWPVVGQNCEMVADVNLKTG---KVG-TRIAecdv---KTKDL-----RS-KSiDVQNS-YISKYQPG---------------KERKTLQTVLeKDYRNTSERSEVVSLAGQFIIHTGQAKLHVMP-HFPGCPFKNNEEVDKWLNYFIMNAPLVCTTVMHSYDPGHNLRLEHTHCYSDHGDAGHYHYDVTPETVSYEGWFAPASKIYRIDEV--------- +>tr|A0A1R3R7E5|A0A1R3R7E5_9EURO Uncharacterized protein OS=Aspergillus carbonarius ITEM 5010 GN=ASPCADRAFT_179137 PE=4 SV=1 +--CFILQPPPLEELRDVIQNGLRNAFETAFVEVTTCPDLSQSPFHLSAPGLCGDEKIADVGGPAYLQPVSDLTKKYTIPKILDLVGMeGQGFAIGAAGGPFHVVGKNSELVPNLARDANGKWQNL-SRYVhIDDDEKMN-----LSMVPkDTKDCGLMANLFISRGHQGESLHIRAKGRRGQLNFPETIQELLRVNYGGRPVSLGGVFLVKQGKAKLHVMT-DFSTSSCPG---PdHEWFRYYEADAPIVCLTAFHSVDyLDWNLRMEHTHCFSESGVGGHYHYDTTPDDVEYEAWLNTAKAVYRIDQP--------- +>tr|A0A146MXI0|A0A146MXI0_FUNHE Ester hydrolase OS=Fundulus heteroclitus PE=4 SV=1 +----QLHAPALEELRGVLQAGLETNFAEVQVSVVECPDLTTEPFLFPVKGLCGNPRITDVGGVPYLIPLPQKHKEYNMNIISKELELPGAFILGAAAAPSRIIGMNAELMPLVLTEAEGRPAVNGSYFSSINPADGQCLQEKYSDKFSDCNFGLLGNLYACEGKPGKVIEVRAKKRTGSNSLVTALRKTLEAQYPEKSLALGGTFVIQKGKAKIHIMPREFSACPLNTNDDVNNWLKHFEVSAPLVCQSVLVSRDPV-------------------------------------------------------- +>tr|E2A095|E2A095_CAMFO Ester hydrolase C11orf54-like protein OS=Camponotus floridanus GN=EAG_15254 PE=4 SV=1 +----DILEPEMEKLAEYLQVEFNKFYNEATVKVVNCPDLRKAPFHLVAPGLCGNTALLEVGSLSNLFPFPRMEKKYDFISFLEtsGRSNDDNFIIGASLYPSSNGHMGELIMNASFspLDEEGMRVKNRSYVAFLAqDHTGENVKLDILNDYNRVKCFLHGNFFISEGKPGRVLEIHAKARREDKELTKVIQHTLQKYYEATstLVGLGGTFVVHNGLVRHHLMPDIGQISleNCSDESRIRNWVKTRILTTPLVAVGTIVNKSSF-------------------------------------------------------- +>tr|A0A1B6G5D9|A0A1B6G5D9_9HEMI Uncharacterized protein (Fragment) OS=Cuerna arida GN=g.40942 PE=4 SV=1 +---KPLYCPSLTDAAEALKDGLSETFETVEVSVVDCPDLTQKPFSLASQGLGGSPTILEVGGVPFLMPLVDRSKVYDFKDMNKVTGVNPAFIIGAGAGPFTYAGVNCELVANLVVKDGeVR-QLSQIAKLKDESKGDEFVTETL--QDSVSSFALLANLFVSEGKPGKVIRVHCANRKGKSDFVTAARDSLLKGFPGKAIGVGGTFLVNGSKVKQHIMA-DFTTTPLDSEEKVT-------------------------------------------------------------------------------- +>tr|A0A1S9RUH1|A0A1S9RUH1_9EURO Ester hydrolase c11orf54-like protein OS=Penicillium brasilianum GN=PEBR_10800 PE=4 SV=1 +---HPRDPPPLGELAAIIQRSLLANFASASVSVVECPDLRQPPFYLASSGLSGNPCIADVGGQANLFPRPNFDAKFNLRSLAKDMQMTegeGGFLIGAGAAPFHDTGYNAELAVNLYTPPGpHVgtsdpdvdRVRNGSRIIQVNPDGSS---CCE--PIGSLNCGLMVNLFGSTGDTGPVLKITARARTGDKNFTNCIRLGLADHYGDsRPISLGGVFLLKAGKAKFHIMP-DFPQEddlPFQDrEKLEKNWLTYHDFEAPVICLTVMH------------------------------------------------------------- +>tr|A0A1X7RMD4|A0A1X7RMD4_ZYMTR Uncharacterized protein OS=Zymoseptoria tritici ST99CH_3D7 GN=ZT3D7_G3732 PE=4 SV=1 +---HTLSPPSLEELAQVLSPALKANFKTSSVTVERCPDLRKPPFYLATEGLSGQESVADIGGQPNLFPQPRLECKYSLLEIAKEMEMSgsKGQLLGAGAGPFHVIGMNSELSPNLSWEKS--fdnvnNLTYYTKIEEDHGKPIA---RCE--KSPCADCALMMNLYGSTGNSGPVLKITARTRTGSqKSFTECIRRALFDKYGDaHPISIGGVFVMKTGKAQFHVMP-DFPPAeqlPWTQgSQ-VNDWLTWHEFIAPIVCLTVFH------------------------------------------------------------- +>tr|T1J8W5|T1J8W5_STRMM Uncharacterized protein OS=Strigamia maritima PE=4 SV=1 +-------QPEANELQSVLEKGLKNSFEEASVQIIDCPNLEKEPFNLAAKGICGRPTLIDVGGVRNLQPVPMRNKVYNLDELTQMTHNPDAFLMGAGGGPFHVTRVNCEFMANIRTSVT-GHGRNLSYIARLDSETEYKLLQIP----ENRECGLMLNALVCEGTKGKVMYVRAKKRTRDTNFITAMRETLKVAYGNKPIGLGGVFLLQKGNAKLHIMP-DFPIYPLIDEATVNSWLKFYDMHAPLVCLSTFVTHDPlEMDLRIEHTHCYSNHGQGGHYHYDTTPDTVEYMGYFVPCSTLYRIDKPPV------- +>tr|A0A0L7L9M9|A0A0L7L9M9_9NEOP Ester hydrolase C11orf54-like protein OS=Operophtera brumata GN=OBRU01_09397 PE=4 SV=1 +--EKALYVPPLEEVVDVLARGLPDTFETVSVSVVDAPDLTQEPFSLTSPG---DVKLVEIGGPPYLVPLVKRDKIYDLHLLLQHLKRDPGflagagagpwpylgvncerprfsgghggwalavpgsqlrgiliahlkrdpgfragagagpwpylgvncerprlpggrggwalavprsqlrgtliahlkrdpgflagtgagpwpylgvncerprlpggrggwalavpgsqlrgtliahlkrdpgFLAGAGAGPWPYLGVNCEGI--INLSVRNGSVEQGTRIVSVEPVGAakgssGFLQQRLPN--TETRTALLGNYLLSEGKPGK--------------------------------------------AKFHVMP-DFSGTALCSDSDVDGWLHYFELSAPIVNVGTLVTGDLGLDLRVQHFHGFSAHGHGGHYHYDTTPDAAHYEGYFSLAHSVVRIDPPAETHALGRD +>tr|A0A0N1I8F1|A0A0N1I8F1_PAPMA Ester hydrolase C11orf54-like OS=Papilio machaon GN=RR48_02211 PE=4 SV=1 +--TKALYVPPLEEMAdaefcqlienvqdkreliamcvAVLSHELRSTFETVEVSVVDCPDLTQPPFDLQAPGISGNATLVEIGGPPYLMPLVQRDKVYDLAALLRHLRRDP-aLLTGAGAGPWPYIGVNCEGI--INLRMQDGAVRQGTRVVSVQPVGAakgssGYLQRRLPD--AETRTALLGNYLLSDGAPGKVLRVVAKRRVGADNFITAIRRALQARYGERGVGLGGAFVLREGRVKHHVMP-DFSSTALCSDEDIDRWLHYFEMRAPIVHVGTLVTADLGLDLRVQHFHGFSAHGDGGHYHYDTTPDSVHYEGYFTPADTIVRVDAPRDTHAFGRD +>tr|H9J011|H9J011_BOMMO Uncharacterized protein OS=Bombyx mori GN=LOC101745847 PE=4 SV=1 +--EKELYTPPLDEVACVLSNGLTTNFKFVEVSVADSPDLTEPPYYLKSPGLTGDAKLVEIGGPPYLVPQVKRDKIYDLAKLLEHLNRDP-aFLAGAGAGPWPYLGVNCEGI--VNLSVRNGTVDQGTRIVSVHPVGApkgssGYLQQQLPN--DETRTALLGNYLLTEGKPGKVIKVVAKNRTGKSNFITSIRETLKTHYGDKVVGLGGAFVLRAGRGYFHVMP-DFSRAPLCSDAAVDSWLHYFELDAPLTVVGTLVTGDLGLDLRVQHFHGFSGGgggaGAGGHYHYDTTPEDVHYEGYFTVASSLIRVDPPVETHTFGRD +>tr|A0A1W4XLR3|A0A1W4XLR3_AGRPL ester hydrolase C11orf54 homolog OS=Agrilus planipennis GN=LOC108745268 PE=4 SV=1 +--YKPLYKPPLQELADVLNQNLTYNFAEVHAEVVDCPDLRKEPFTLASEGLGGNPRVVEIGGVPYLAPIAQLNKVYDLKDIERFSGL---ksaFIVGAGAGPHPYAGVNCEGI--INMNVKDGKVEQQTRISKVVPSDGSQVQEILPN--SETRIALLANLFYSEGKPGKVLKVHVKKRIGSDDFVTSIRETlAKRYFDDKIIGLGGTFLLKEGKAKQHVMP-AFSKTPLNSGKDIDNWLKFYNMSAPLIAVGTLETGDPGLDLRVQHFHSFSHHGEAGHYHIDTTPETVEYLGFFNIGEYVYRVDAPAVSHSFGRD +>tr|A0A1W4VTT6|A0A1W4VTT6_DROFC ester hydrolase C11orf54 homolog OS=Drosophila ficusphila GN=LOC108100296 PE=4 SV=1 +--EKPLHVPCLSEIQRVIQGALSENFKTVDVSVGPCPDLEEPQFGLVESGLGGNPTLLEAGGPPYLRPLVQREKLYNLKEITRKAQGS--geiFAIGPGAGPWPIRNSNCEGI--FNFSLSEKDElKQGSYTATV-----rgdqeECVLERIPE--TEARCALILNLFLSEGKPGEVLRISAKQRTGKENFVECIRKGLEQHFGDKVVGLGGIFVVKKGCVHQHVMR-DFSKTPIHTQEQIQEWLKFYEMPAQLNAVGTLVTKDLGLDLRLQHFHSFSFENWGGHYHYDTTPDVVEYEAYLNVAERVIRVDRPVVTDQLGRD +>tr|A0A182FFU6|A0A182FFU6_ANOAL Uncharacterized protein OS=Anopheles albimanus PE=4 SV=1 +--EKPLHMPTLQELRDVLAVGLKSSFTTVDVEVVECPDLTRAPFHLAGAGLCGSATLVEIGGPPYLLPTVDRSKLYDVIEVSKRALphganSPKSFItIGAGAGPFPLVDSNCEGMFNVHY-SPPGTIVSESHLAIVAPDAGTMSIRKIPN--TETRCALLANLLVSEGKPGPVLKVHCKRRTGNKDFIASIRTCLADRYGDdRTVGLGGVFLLVEGKAKQHVMS-PFSATPIHTEEQLNEWLNFYDMPAPLINLGTLVTNECDLDLRLQHFHSFSTHGHGGHYHIDTTPDAVEYEGYFVVGERIVRVDKPVVTHKFGRD +>tr|A0A182MQZ2|A0A182MQZ2_9DIPT Uncharacterized protein OS=Anopheles culicifacies PE=4 SV=1 +----------------VLAVGLKSCFATVNVEVVECPDLSKAPFHLAGCGLNGTPALVEIGGPPYLLPTVDRTKLYDVVSIAKRALhdDQKAFIaIGAGAGPFPLVNSNCEGMFNLHY-SPPGIVMSESHLAMVSPERE-VIVRKVPN--TETRCALLGNLLVSEGNAGPVLKVSCKRRTGNKDFIASIRTCLEDRYGEKTVGMGGVFLLQAGKAKQHVMS-PFSTTPIHTEEQLNQWLNFYDMPAPLINLGTLVTNECDLDLRLQHFHSFSTHGHGGHYHIDTTPEVVEYEGYFVVGERIVRVDKPVHTHKFGRD +>tr|A0A0A9XUG4|A0A0A9XUG4_LYGHE Cytoplasmic tRNA 2-thiolation protein 1 OS=Lygus hesperus GN=GF12710 PE=3 SV=1 +-----LDTPSLAEVRDVLARDLKKTFDYVDVQVVDCPDLTEEPFFLAGKGLGGETSLIDLGGPPYLLPLVKRDKVYDFKQLVKQLKVTPSLLMGACAGPWPYFGKNCEGVCNVLVDGDN-YFKSCSYVGKVTDGDEklECLPIPDSE----TRFALMANLYCSQGKPGKVLKVNCKKRTGKKDFITAIRTGLAAGFPNKYVGLGGAFLLKEGRAKQHVMR-DFSKTPINTEEELNNWLTFHDMSAPLVAVGTLISNEvPDFDLRVQHFHSFSKHNEAGHYHYDTTPETVEYLGYFNVAERLHRVDKPKQTHQLGRD +>tr|A0A1J1I839|A0A1J1I839_9DIPT CLUMA_CG009848, isoform A OS=Clunio marinus GN=CLUMA_CG009848 PE=4 SV=1 +---KELFVPEMETLCSVIETGLKSNFSDVSVSVVDCPNLSQAPFHLASSGLGGDATLVEFGSPVYLLPLVNKSKIYDIVELLRNISSyesKEFFTCGAGAGPFPIFNQNCEGMLNIRVGSDGTL-KNETHVARIVP--GGVELSKVPD--QETRCALLGNLYLSEGKAGKVLKVTAKRRTGSENFISSMRLALAEYFtDDKTVGLGGTFLIKEGKAKQHVM-DEFSKVPLYTEDDVNKWLTFHEMSAPLIAVGTFVTNEADLDLRLQHFHSFSKHGEGGHYHYDVTPDTVEYEGYFAVGRRIIRIDKPEQ------- +>tr|W2TIQ2|W2TIQ2_NECAM Uncharacterized protein OS=Necator americanus GN=NECAME_17820 PE=4 SV=1 +----------------------------------------------------------------------------------------------------------------------------------------------------------MGDLGVSAqPGPGEVVHIKCSQRIGKESFPQCIQESLARHYGQSCVSLAGIFALLRGNASVHIAP-DFPDKSFRSREEFDQWLQIFNLSAPLICASVINSYDPGFGLRMHHTHCYSSHNDAGHFNNDITPETVEYEGWFTAAEKIYRID----------- +>tr|A0A1E1WGP1|A0A1E1WGP1_PECGO Uncharacterized protein (Fragment) OS=Pectinophora gossypiella GN=g.19230 PE=4 SV=1 +----------------------------------------------------------------------------------------------------------------------------------------------RRLPPTETRTALLGNYLLC-dGRPGKVIKVVAKKRIGESNFITAIRETLKNHYGEKVVGMGGTFVVRAGRVKHHVMP-DFSAAPLCSDSDVDAWLHYFEMRAPITHVGTLVTGDHGLDLRVQHFHGWGEHGDGGHYHYDVTPASVEYEAYLTPAASVVRVDAP--------- +>tr|A0A1Y3ANJ6|A0A1Y3ANJ6_EURMA Ester hydrolase C11orf54-like protein (Fragment) OS=Euroglyphus maynei GN=BLA29_006393 PE=4 SV=1 +----------------------------------------------------------------------------------------------------------------------------------------------RLDKCKYPEFGLLGNLFISEGKPGKVIEIIVEKRLGKENFPESIQKILRENFPNKPISLGGVFIIEKGRTKLHIMP-DFSPEPLRTNDDVDKWLRYFDMDPPLICLTTLHSIDPGLDLRMEHTHCFSDHNQGGHYHYDITPDIVRYTGYLQIVEAIYRIDRP--------- +>tr|A0A0G4IS31|A0A0G4IS31_PLABS Uncharacterized protein OS=Plasmodiophora brassicae GN=PBRA_006131 PE=4 SV=1 +----DLFAPALDDAVAPIAAFLRDRYEHASVEVVECPNLLS--WGLAMPGLGGQPRLVDVGGVPNLLDPAHQDKSFAIGDILDCAGLPTGCVLGAASGDAAWAKGNTELMPCASRH------TCRSKSARVG-ADGRCVLDEYDWDRVGF----LANLFVCQGVPGPVLEVRARGRRLPEdhsdNFVGNIRGALLQRFPGRAIGLGGAFTMKKGLFKAHVMPD-FKDTVMVDGPEVQEWLKYYEMGPGATFLSTMLTQDPTpdgaLNLRLEHTHFFNQTaGEGGHYHYGTS-LDVDYVGYFALAERVYRMEN---------- +>tr|A0A0P8YN63|A0A0P8YN63_9PROT Uncharacterized protein OS=SAR11 cluster bacterium PRT-SC02 GN=JI56_00575 PE=4 SV=1 +----KFNNPSLEILAEALKKGLKANYQEVTVEIINCPNLRE--WNCPSEGISGNERIIDVGGEPYMHDKQFIGTEFDYEEIAKNIGSEKSYALGAGSGAMSCLGGHCGELIInenLITN------ESNSIIAQVN-KNKECVTKKYTEKKHGG----LANIFFSDGKIGKVIKIKLKKRIGKQgs-LPQAMRSALFeniIIQKNRHVALGGVFRVLHGGVKSHVQPD-YEDIKYEYyDSklmkCTKDFLQFYEpVGPKLQCYSVLWTGDPTggdLNLREsgEHTHFHSyNNkPEAGHYHFDVTPNDIEYECYFNIAHEVFRVNN---------- +>tr|A0A1C2AY87|A0A1C2AY87_9PROT Uncharacterized protein OS=Pelagibacteraceae bacterium GOM-A3 GN=AKH20_00875 PE=4 SV=1 +----IFKKFKLEEISNALEKGLSKNYDSVKAEVIDCPNLRN--WDCPSEGMSGNQRIIDVGGEPYMHDPKYLGTEFDYFEISKMIGSERSYALGAGSGAMSCLDGHCGELVInenFITK------ENKSLIARVG-KDKQCIVEDYTASKHGG----LGNVYYSDGVKGKVVYLKIKKRIGKQgs-LPQSIRAVLSenlKIGNKDHIALAGVFRVLNGKIRSHVQPD-YKDIKHEYyDPelmkCTKDFLQFYEpVGPKLQCYTVLWTGDPTggeLNLREsgEHTHFHSyEHkNDAGHYHFDVSPDEIEYEGYFNIAQEVYRVNN---------- +>tr|A0A1J1I839|A0A1J1I839_9DIPT CLUMA_CG009848, isoform A OS=Clunio marinus GN=CLUMA_CG009848 PE=4 SV=1 +---KETHKPSLDEIRNVLEEALKKNFNEVSVEIVDNPDLKSEPFYLASSGISGNPLIIEYGNDDYLLPLVDKSKVYNLIPTIREIetyKEKNFYVCGAGAGPFPLYDQNCEGiynMKVFKNG----TIDNQSHIARTQ---G-SGTETLKLPNNETRAALLGNLFLSEGNDGKVLKVIAKNRTGEENFISAMRLGLSEKYSeDEVVGLGGVFVMKKGIANIHVMD-RFSENPINTDEELNNWLTFHEMPAPLIALGNFVSHQTDFKLRYHHFHCFSKHNHGGHYHYDVTPDIVEYEGYFNIAERIILIDKSF-------- +>tr|B4H5I4|B4H5I4_DROPE GL16084 OS=Drosophila persimilis GN=Dper\GL16084 PE=4 SV=1 +-------------------------------------------------------------------------------------------------------------------KPLHVPPLpelqnviQGALRGNFAPSWRACVLEKIPHT--EPRCALLLNLFLSQGAPGQVLKISAKQRTGEQNFIECIRKGLEDHYGDRVVGLGGIFLIKKGAVHQHVMR-DFSSTPIHTDEEVNEWLKFYDMPAQLNAVGTLVTKEHDLDLRLQHFHSFSFSNWGGHYHYDTTPDIVEYEAYLNVAERVVRVDKPLSTHKVGRD +>tr|A0A1B0FJ72|A0A1B0FJ72_GLOMM Uncharacterized protein OS=Glossina morsitans morsitans PE=4 SV=1 +-------------------------------------------------------------------------------------------------------------------KSLHKPPLeelqnglGGCptllelggapyllpkvqkdklydikaicrksmgegkilavgagagpyplrttncegifnlsisaqdeikngsYTAKITGLQEDCLLEPIPDT--ETRCALLLNLYVCRGEPGPVLKITCKKRTGHMNFIECIRKGLYEKYQDKC------------------------------------------MPGTLHAVGTLVTHEHDLDLRLQHFHSFSRTKWGGHYHYDTTPDTIEYEAYFNVAERIVRVDKPKTTHKFGRD +>tr|A0A158P7C4|A0A158P7C4_ANGCA Uncharacterized protein OS=Angiostrongylus cantonensis PE=4 SV=1 +---IETLKPSNSELLPIVESALKSNFKDVTVEVGPCPgkivcvreqqlpfpvvvDLSVEPFSMTSSGFGQNLVIAEVGGPGNLFPKINKEKEFDLKEICNTCQSPFSFVFGPGAGPWKVVGRNCEMVADAnfatakvATK-----------IASLPPgyS-PPYKMGV----IDSPKFSLMANLAVSEPGPGEVLHCKCSVRIGKDNFPETIRKALAKHYGKRCVSLAGIFLLGEGEAKLHVMPD-FPGCQFSSTEEVSL------------------------------------------------------------------------------- +>tr|F1LEY2|F1LEY2_ASCSU Ester hydrolase OS=Ascaris suum PE=2 SV=1 +---IVLKTPPLEELSSILCAELKKNFVDVSVDIVDCPNLRAPPFRMSGAGIGNDLRIGEVGGIGNLFPSPKTDKFFNLKKICETCEMPKAFVFGPGAGPFHIVGNNCEMVADAdfttdhqnnvATK-----------VSRVVPNGKGYEMST----IDNADFVLMANLAISDGFpAGKVLRVHAAKRNGEMNYPGAIRKALIGYYDGqrMAEVFRN-----ESAISMCIGIA-FE------------------------------------------------------------------------------------------- +>tr|H2VJ38|H2VJ38_CAEJA Uncharacterized protein OS=Caenorhabditis japonica PE=4 SV=2 +---IENHVPSLDELKEVFIKSLTENFETVTVDITTCPDLSKPPFNQTSSGFGENLRIAEVGGPGNLFPGFHIDHQFDITTIGKVCELPEASVFGPGAGPWPVVGQNSEMVADVnlktgrsATR-----------IAEIKPgnGNKKYLQRS----IDQPKFSLMANLALSNADkSASVVHFKVSVRKGEKNLTLCIRDGLQKHFGDK-------------------------------------------------------------------------------------------------------------------- +>tr|A0A1F5LXL7|A0A1F5LXL7_9EURO Uncharacterized protein OS=Penicillium arizonense GN=PENARI_c001G10941 PE=4 SV=1 +---HPRDPPPLDELAAIIERSLLCNFSTASVSVVQCPDLRHAPFNLAGSGLSGNTRIADIGGQQHLFPQPVLDAKYSMLSLAKDMEMSsaKGFILGAGAAPFQDIGQNAELAPNLsweaknntsdLTD-----------TNSLNVesGtrvikisqDNSPKCEQ----LPSTNCALMINLFGSNGETGAVLKISARTRTGEENFTNCIRNGLRDAYGDsRPISLGGAFLLKSGSAKFHIMPD-FPAEDQLpfrDRQQLEK------------------------------------------------------------------------------- +>tr|A0A1V6PWG5|A0A1V6PWG5_9EURO Uncharacterized protein OS=Penicillium antarcticum GN=PENANT_c028G11198 PE=4 SV=1 +---HLRDPPPLDDLATVIERSLLSNFATASASVVQCPDLREAPFNLAGSGLSGNARIGDVGGQQHLFPQPVLDAKYSVLSLAKDMEMSptRGFILGAGAAPFQDIGQNAELAPNLswkandsasdFTD-----------KSSLSLenGtrvikinqENSPKCEK----LPSTNSALMINLFGSDGETGPVLKVSARTRTGEENFTNCIRNGLRDTYGEsSPVSLGGAFLLKSGSAKFHVMPD-FPPEDQLpfrDRQQLEK------------------------------------------------------------------------------- +>tr|A0A147B707|A0A147B707_9ACAR Ester hydrolase c11orf54 homolog (Fragment) OS=Carios mimon PE=4 SV=1 +----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPVGLGGVFLLKQGKAKLHVMP-HFSTKPLTTADDVNGWLKFFNMSAPLVCLGTLMSHDPGWDLRVEHFHCFSDHGEGGHYHYDVTPEEVEYLGYFSVAEYMYRIDAPDVTHNIGRD +>tr|K7I0V9|K7I0V9_CAEJA Uncharacterized protein OS=Caenorhabditis japonica PE=4 SV=1 +----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------XVVSLAGQFIIHTGKAKLHVMP-DFPGCPFADNAEVDKWLNYFEMDAPLVCATVMHSSDPGHNLRLEHTHCYSDHGDAGHYHYDVTPLEVSYEGWFAPASKVFRIDEVSGR------ +>tr|S4P157|S4P157_9NEOP Ester hydrolase OS=Pararge aegeria PE=4 SV=1 +------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MP-DFSATPVRTDAEVDAWLHYFDMRAPITHVGTLVSGDLGLDLRVQHFHGFSQHGDGGHYHYDTTPGEVHYEGYFALAGSVVRVDAPAETHAVGRD +>tr|Q5AY31|Q5AY31_EMENI Uncharacterized protein OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN=AN6799.2 PE=4 SV=1 +-------PPPLSELGSIIARALQQNFAHASASVTQCPDLRKPPYGLAASGLSGNPRIADVGGQANLFPSPNFNAKYSLLSLARDMEMsaERGFVLGAGAAPFQDIGHNAELAPNVAWQAreGVKELDlgNPDCVDIVNETRIVevVAGEVDSVSCWrapSANCALMVNLFGSSGLPGPVLKITARGRTGPANFTSSIRAGLLAAYGDsHPISMGGVFLLKAGKARFHVMPDFPAPedLPFKDRRvLEQEWLKYHTSEAPVVCLTVFHSADPeGLQLRMEHTHCFDLEGcrKGGHYHYDLETDnggEVEYEAYLNVAEVVYRIDRP--------- +>tr|A0A136IYY9|A0A136IYY9_9PEZI Uncharacterized protein OS=Microdochium bolleyi GN=Micbo1qcDRAFT_196324 PE=4 SV=1 +---YPLSPPSLSALAAVLQPALSRNYAHCSVSVSPCPDLRQPPFHLAAQGLSGDEKIAEVGGQSNLFPSPDLSAVWSLPEIARDAmgmDAARGMLLGAGAGPYRDVGQNSEWAPCYSWEDN--KVRNESRCALVRKDTGKVEVR----KQDSLGCALMCNLFGSRGEPGDVLRITARRRTGDAaSFTECVQAALREAYGDAegstVVSLGGVVLIKKGLAKYHVMPDFpdEKDRPFRDLDQLMKWLTWHEYRGPIVGLTVLHSADPGGkvGLRLEHTHTFSATGEdaGGHYHYDIEDeggEDVEYEAYFNTAK----------------- +>tr|Q0CB59|Q0CB59_ASPTN Uncharacterized protein OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=ATEG_09075 PE=4 SV=1 +-------PPALEELAAIIQQSLQSNFETASASVVQCPDLRQPPFKLAAPGLCGEACIGDVGARGNLFPRPNLNAKYSLLSLAEDMKMSteKGFLIGAGAAPFQDIGQNAELAVNLswQGRSDGAEFNEPSSLVVENKTHVVRISQDSTSTCKtttSTNCALMMNLFGCHGEAGPVLKVTARSRRGKDNFTNCIRHGLYAAYGDtRPVSLGGVFLLKSGKAKFHIMPDFPPedQLPFPDREYmEQRWITYHVFKAPIVCLTVLHSADPeGLGLRMEHTHCFEieGHRQGGHYHHDINdgGDEVEYEAYLNAASLLYRIQ----------- +>tr|A0A016RWU6|A0A016RWU6_9BILA Uncharacterized protein OS=Ancylostoma ceylanicum GN=Acey_s0351.g3242 PE=4 SV=1 +-------KPSNNELRSVIETILWKNFKNVQVEVASSPDLTAAPFRMTSNGFGKNLVIAEVGGMGNLYPDLHKEKQYDIQEICEKCGAPKAFVFGPGACPSRVIGAGELVADA--NLSENKVTSK------VTTLVKN-HFLKYKTKIiNSTKFSLMGNLVVSEQpGPSEVVHVKCSERTGEDSLPGCIRKGMAEHYGQSCVSLAGIFLLLRGKADVHIIPD-YPEKPFNSMDEVEKWFQIFNVSAPLVCASVLHSYDPGYKLRIQHTHCYSDHDDAGHFYNDTTPKIAEYEGWFTAAEKIYRIDE---------- +>tr|A0A068X426|A0A068X426_ECHGR Ester hydrolase C11orf54 protein OS=Echinococcus granulosus GN=EgrG_000294200 PE=4 SV=1 +-----------YDVCSTLECYLTPYFGHLTAKVVECPNLNQRPFYLGRSGICGDSTIANVGSLDYLLPCADPSRLYDIMDITKYTGHCQGMILGGGVGPFQCYKKPCEVSTEITYST-RGLQCNRSLIGFCSKECGSP----SSERASNTLLSSLGQIFITEAMPGKVVEIVAHKRIGGPSIIDLMQAALYDKFSkqELPMALGGVFYLQNSGAQASVLC-ELPQEPYHTFPCLKKYQTSFNIDGPIIGVGTVLSHDPkKMGFSMASFYCWNAsRLLTGHFENDICPEKATYTVYLTPAKKLYRQDKPVHN------ +>tr|A0A0R3WZJ8|A0A0R3WZJ8_HYDTA Uncharacterized protein OS=Hydatigena taeniaeformis PE=4 SV=1 +--------------VEVFRNRLKEYFKSTKVNVVPCPDLTSPPFGLLRPGLAGQSVVCDVGSMSYLLPVADTSKKYSFDQVVESSGVHSGHLLGAGGGPFFTHGKTCEMAASLQYEN-DKIISNSTLHGVYGEQTGTP----QVIKATDNNFGLVGQLLSTEGLPGSVVvcihtiflflslyifwhqviEVDVADRLKEGSVHVFLREALTDAYGklDKPVALGGVFVLTDSRARFHVLQPNFPPHPVDTPARMAEFIKVFEMDPPVLGMGTLISHDPyGIDLKLEHFHCYNEaKNLAGHFYWDTEPEKAHYRLYLTVAKGLLRIDPKKKT------ +>tr|A0A0X3PY77|A0A0X3PY77_SCHSO Ester hydrolase C11orf54 homolog OS=Schistocephalus solidus GN=CK054 PE=4 SV=1 +-----------VEIARELKRGLQPLFGFVDAKVVECPNLTRKPFNLPRSGISGENTIACVGSHDYILPSISCRKQYDLMDVANACKVRAGEILGGGTGPYPTTGHPCEMVAELCYCN-GSISCNRTLHAYSDKSGSAP----NLIKATDTKFHSSAQLFVSEGNEGWVIEVIAKRRLCEGSIGKFLHQALQSRYGrgDEPMALGGVFLLEGSGAKYHVLS-ELPNEPYHTFPDLKSYLKCFEMKAPIIGMGTVLSHDPnDLGLHMHSFHIYNVeRNVAGHLETDTDPEAASYRIFLHPASHICRMDKPVY------- +>tr|Q0MQZ2|Q0MQZ2_TALMA Mitogen-activated protein kinase OS=Talaromyces marneffei PE=3 SV=1 +---ISRSPPTLSELAEKLQGSLSANYERSSVTVVPCLDLREPPFLLAHEGLSGDEKVADVGGQTHLYPRPMRDKTYALISISREMEIEvgesheQVMIIGAGAGSSDIVGQNCEMAINFGWRygggggggggggggvPQGSWRHNGGRYVKIEPGTDSVLLEKTDSA--RWWFGLMGNLFASDGGPGDVLKITARKRVGEEgSFTECIRKALHAAYGDSQIvSLGGVFVIKSGKARYHIMPDFPpEELPFRDRQRFNDWLTYHDFKGPMTCLTVLHSVDPDkkLGLRMEHTHALSTVGEnaGGHYHYDVEEekEEIEYEGYFNTAKALYRIDKPEF------- +>tr|A0A1Z5TUE2|A0A1Z5TUE2_HORWE Peptidylprolyl isomerase OS=Hortaea werneckii EXF-2000 GN=BTJ68_00352 PE=4 SV=1 +------SPPTLGEICSTLRPALKANYSDSSIEIVTCPDLTAPPFHLASQGLSGKESIADIGGQAHLFPRPLKEKKYSLVDCAKSMGMSqqRGLLIGAGAAPWHVIGQNAELAPNVSWEGsmdEESRVRNQTFVTRVESHGGQVRC----ERLPSMEFALMMNLFGCEGVTGDVLRVTAKGRRGQqGSFTECLRQALHAEYGGeRQVSLGGVFVMKKGKAVFHVMPDFPpeEALPFPSHDAVNEWLTFRQFSAPIVCLSVLHSADPEkLGLRMEHTHCFSTdKDEGGHYHHDILPD----------------------------- +>tr|A0A074ZFU1|A0A074ZFU1_9TREM Uncharacterized protein OS=Opisthorchis viverrini GN=T265_14086 PE=4 SV=1 +-------CPGLGNLTGFMS----GCFSKVACQVVDCPNLKDPAYALNSAGLCGSETLCDIGSFDYLLPVPNKEKRYDLLDAFSLSHVGSGFIMGAAAGPHFVAGINSELVANLS-ATDGKVLQNGSYCGSYDAKN-NLPVSTLSET---SLFAMVGQMFLCEGKPGKVIQLTVSGRTREGKFDALLREALASKYGalDRPVGVGGVVVQETGKCLFHVLP-EFCEEPLDTPEKLKQWLKFFEMEAPVVAVGTALSHDPQkWKIRLEHFHCFNRDRtKSGHCHFDSDGPTASYTAYLVPGKRLLRVDPPK-------- +>tr|A0A0R3U295|A0A0R3U295_9CEST Uncharacterized protein OS=Mesocestoides corti PE=4 SV=1 +---------------------LAPYFRHLTTKVVECPNLGAKPFYLGRAGISGDATLANVGSYDYLIPCADHGKMYNFVDVARYSGISFGMVLGGGIGPFQAYQKP----------CECEVP--------------------ISERASNNFFSATGQFFITEATPGKVIELKAAGRVNCHNIFDLIQKALYNKYSksSSPVALGGVFFLQNSAVEVNLLN-DLPKEPYHTFPCFKEFQTTFKIEGPIIGTGTIVSHDPnNQDLVTQSFYCWDTeKQLTGHFENDICPDMANYTVYLYPARNILRLDKPY-------- +>tr|A0A0R3U4D3|A0A0R3U4D3_9CEST Uncharacterized protein OS=Mesocestoides corti PE=4 SV=1 +---------------------IKDHFKSVNVRIVPCPDLKASPFRLLCSGLSGQNIVCDVGGMSYLLPVPDKTKMAANVRFEDSK-ISSNSTLHG------VYDES------------TRSP--------------------QVLAATDNNFALLAHLLATEGLPGDVIEVDASGRLKEGAPYVFLREALTSAYGklDKPVALGGVFMLTGSKGRFHvlfieaavplLQP-DFPDHPVDSPSRVAEFLKFFEMEPPVMGMGTLVSHDPfGIDLKLDHFHCYNEkRDLAGHFYWDTEPQTAHYKFYLTVAKSLLRIDPKP-------- +>tr|A0A1L1ST86|A0A1L1ST86_MOUSE Uncharacterized protein OS=Mus musculus GN=4931406C07Rik PE=1 SV=1 +CSEFSFHMPSLEELAEVLQKGLTDNFADVQVSVVDCPDLTKEPFTFPVRA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|C5M1Q2|C5M1Q2_PERM5 Putative uncharacterized protein OS=Perkinsus marinus (strain ATCC 50983 / TXsc) GN=Pmar_PMAR027336 PE=4 SV=1 +---------TIDEVADALRDGLAKVFKKIDVDVVDCPDLRQAPYLCskPGLGSPGKGSVVDCGGCALLYPKVDITKEYDMRQIASIVDnythvgggdeeayppssaestvagsptersnslpshhTPQAFhILGAGACAYSVTGQNGELA--INCADEGDPHTACGI---V---CEDSLPEK--KNYHSYLSGPLCNVFKCSGAPGKVLRVHAAARMDPEvgsDIVETMKSILETAFPRDVLGLGGVVLVKKGKVMIHVMH-DFTVKPIRSQKFIdSEWLRMKEADTPFTNYTVFVTNPPAtLDLRPSHTHGFNDK-VAGHYHYDTTPLRVDYECYLQLADNIYRVDRAS-------- +>tr|A0A016S224|A0A016S224_9BILA Uncharacterized protein OS=Ancylostoma ceylanicum GN=Acey_s0312.g2179 PE=4 SV=1 +---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FVRTQKVDKWLRFFTMKAPLVCASVFHSYDPGHKLRLEHTHCYSEHGDAGHYHYDTTPETVVYEGWFTAAEKIYRIDE---------- +>tr|A0A1B6FX27|A0A1B6FX27_9HEMI Uncharacterized protein (Fragment) OS=Cuerna arida GN=g.40946 PE=4 SV=1 +------------------------------------------------------------------MPLVDRSKVYDFKDMNKVTGVNPAFIIGAGAGPFTYAGVNCELVANLVVKDgEVR---QLSQIAKLKDESKGdeFVTETLQDSVS--SFALLANLFVSEGKPGKVIRVHCANRKGKSDFVTAARDSLLKGFPGKAIGVGGTFLVNGSKVKQHIM-ADFTTTPLDSEEKV--------------------------------------------------------------------------------- +>tr|A0A1B0DGT9|A0A1B0DGT9_PHLPP Uncharacterized protein OS=Phlebotomus papatasi PE=4 SV=1 +--QKELFVPDTQELKEVLTLGLKKNFEEVSVDFVECPDLSKEPFNLASSGLCGNPTIIEYGGAPFLLPLVQRDKLYDLDEICQKICRFrnisEYLAVGAGAGPYVLCNTNAEGIFNLKR-NADGSIVSKSHLALVNAEKN-CERRSIP--SSETRSALLGNVYLSEGKGGQ-------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|T1GJ03|T1GJ03_MEGSC Uncharacterized protein OS=Megaselia scalaris PE=4 SV=1 +--EKSLHVPELDEIVQVLQSALSRNFQEVTVEIVDCPNLTAEPYSLVCEGLNGSLTLMELGGFATLLPLEDKGKVYDIVETSRKIMKGkDLAIIGTGAGPVSLEKSNCEIILNMNI-PLKGNLENKSIAIRINEDDE-ISLDPIN--D-QQIFSYLVNIFLCEGKSGK-------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|A0A016S2V2|A0A016S2V2_9BILA Uncharacterized protein OS=Ancylostoma ceylanicum GN=Acey_s0306.g1982 PE=4 SV=1 +---INTLKPSNHELRSVIEAALWKNFKNVQVEVEKCPDLTAAPFHMTSPGFGRNLVIAEVGGWGNLFPNLHKEKLYDIKEICNTCGAPKAFVFGPGGCPPSAVGVNGELVADANL-S--ENKVSSKVTIQLDHY-T-SPYKTLF--VNSTKFVLMGNLAITPEPGP--------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|A0A0R3PRG0|A0A0R3PRG0_ANGCS Uncharacterized protein OS=Angiostrongylus costaricensis PE=4 SV=1 +-------------------------------------DLSVEPCSMTSSGFGQKLVIADVGGPGNLFPKIHKEKEFDLKEICKACQSPFSFVFGPGAGPWKVVGRNCEMVSDANLTTAKVaTKIASLPPGHSPP-YKMDVID--S-----PKFNLMANLAMSEPGSGEVVHCKYSVRIGKDNFPETIRKALVKHYGES----------------------------------------------------------------------------LGHYYYDTTPDTVAYEGWFTAAEKIYRIDE---------- +>tr|A0A0N4X8W7|A0A0N4X8W7_HAEPC Uncharacterized protein OS=Haemonchus placei PE=4 SV=1 +---------------------------------------------MTSTGFGRKMVIAEVGGPGNLFPVIHKEKDFDLKEICNGCEAPSSFIFGPGAGPWQVVGRNCEMVADANFSSSKViTAIC-------------HVIS--S-----PKFSLMANLAVSaEPGPAEVVYCKASVRTGKDNFPETIRKGLAKHYGNKCVSVAGVFMMLKGEAKLHVMPDFPGCNFSSREELEKQWLRFFTMRAPLVCASVFHSYDPGHKLRMEHTHCYSNHGDAGHYHYDTTPDTVVYEGYFTAAEKIYRFDE---------- +>tr|A0A0N4YTH1|A0A0N4YTH1_NIPBR Uncharacterized protein OS=Nippostrongylus brasiliensis PE=4 SV=1 +---------------------------------------------MSSNGFGKNISIAEVGGMGNLFPRLHKEKEYDIKEICELCDKKSAFVFGPGACPKSVMGTTGELVADV-------aSKVTNLVNNHSSP-YKTCEID--S-----PKFNLMANLAISeQPEPAEVGNLTV--RVDGSDVPEKL-----------WPE----------------------------------------------------------------------GNLERHYYNDVSPKTVTYEGWFAAAERIYRIDE---------- +>tr|A0A016S202|A0A016S202_9BILA Uncharacterized protein OS=Ancylostoma ceylanicum GN=Acey_s0312.g2181 PE=4 SV=1 +-------KPSNAELRSVIEDALKTNFKNVEVDVTTCPDLSAAPFSMTSNGFGRKLVIAEVGGPGNLFPNLHKEKEFDLQDVCKECHAPSSFVFGPGAGPWPVVGRNCEMVADANFASSKVATKIASLvEGHSTPYK-------MS-IIDSPKFSLMANLAVSgEPGPAEVVHCKCSVRVGKDNFPETIRKGLAKHYGKMCVSLGGVFLMREGEAKLHVMP-DFPGCPFKAREEVCA------------------------------------------------------------------------------- +>tr|R7THP4|R7THP4_CAPTE Uncharacterized protein (Fragment) OS=Capitella teleta GN=CAPTEDRAFT_97025 PE=4 SV=1 +-----------PNIASVLQDGLSRNFGQVEVSVVDCPNLTQEPFGLACEGLGGHPRLADIGGVPNLVPLAQKKKViFDLSKVPEWTELPDAFMLGAGAGPRHVEGIN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|A0A068XCH7|A0A068XCH7_HYMMI Ester hydrolase C11orf54 OS=Hymenolepis microstoma GN=HmN_000758700 PE=4 SV=1 +-----------------------------------------APLVFKPARLSGQNVVCDVGSMKYLLPVIDKSKRYSFDEVAELSKIIHGQLLGAGAGPFFIHNKSCEMAANV-EFSDSKIISNSTLHGVYNET----TYEPEVIRATDNNFALLAHLLSTEGLPGSVIEVDVSGRLKEGSAYVFLREALTSAFGKlaKPVALGGVFALNDSKARFHVLC-GLPDHPVDTPEKVAAFVKHFEMEPPVLGVGTLVSHDPyNVDLKLEHFHCYNEaQTLAGHFYWDTEPEKAHYRFYLAVAKNLLRIDP---------- +>tr|A0A0R3T6Y0|A0A0R3T6Y0_HYMNN Uncharacterized protein OS=Hymenolepis nana PE=4 SV=1 +-----------------------------------------APFKLNLSGLTGQNVLCDVGSMKYLLPVPDKSKRYSFDKVAELSKVVQGQLLGAGAGPFFTHNKSCEMAANV-KFSGSKVISNSTLHGVYNET-------PEVIRATDNNFALLAHLLSTEGLPGSVIEVDVSGRLKEGSTYVFLREALKAAFSKlpNPVALGGVFVLNDSKARFHVLC-GLPDDPVDTPEKVAAFVKHFEMEPPILGVGTLVSHDPyNVDLKLEHFHCYNEaQTLAGHFYWDTEPENAHYHFYLVVAKNLLRIDP---------- +>tr|A0A1I7XMR5|A0A1I7XMR5_HETBA Uncharacterized protein OS=Heterorhabditis bacteriophora PE=4 SV=1 +-------------------------------------YLSKAPFNMTSRGFGNGLRIAEIGGPSNLFPKLHKEKAFDLNEVCATCDAPHAAVFGPGAGPWPVVGVNCEMVADANL-S--QGKVNAIYLTFlilishsvlskvtfvhnlyIQTATKIAYIeenssNKYQTKIIDsTKFSLMANLAVSENdDPSEVVHFKCSIRTGQLNLPETIRRAIAEHYTDKPVSLAGLFILHEGEAKLHVMP-DFPSCPFNNTDEVI-------------------------------------------------------------------------------- +>tr|A0A0R3SZD7|A0A0R3SZD7_HYMDI Uncharacterized protein OS=Hymenolepis diminuta PE=4 SV=1 +---YGVHEVSMEEVAKILQNGLKDCFKEVRVNVANCPDLTKAPFRLSLAGLSGQNVVCDVGSMKYLLPVADKSKKYSFDKVAELSKVIQGQLLGAGAGPFFTHNKNCEMAANVN-FSDSKVIsnstLHGVYDETTNKPE--------VIRATDNNFALLAHLLSTEGLQGSVS------------------------------------------------------------------------------------------------------------------------------------------------ +>tr|A0A0J7NBA3|A0A0J7NBA3_LASNI Ester hydrolase c11orf54-like protein OS=Lasius niger GN=RF55_10415 PE=4 SV=1 +----------PDKLAHVLEDGLKRTFVNVSVKWVECPDLTQEPFNLAAPGLCGKPALMEVGDLSYLNPNPRKDKIYHINPILKF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|A0A0J7KEV3|A0A0J7KEV3_LASNI Ester hydrolase c11orf54-like protein OS=Lasius niger GN=RF55_11667 PE=4 SV=1 +----HLNLPDLSEVKNVLEPALREYFNEANVSVVPCPDLRESPFHLAAPGLSGETIIMKMGGTEFL--WI-------------------------------------------------------------NPT------HN--------------MDKSCNGDPGYVLKVNAKGRRTNVNFPTAIQTGLQRRYEpNDFIGLGGTFVIKNGIVRNRLRCP---SLDLNSPSEL-----IHHTSTPLVAVGTILSRKTHtsyyfeeglFEGnaeptillhqlqesefetEVFHTFACNRVDVGGHFLNDFSPLDTEYEGYFNLATKFIRVT----------- +>tr|A0A0J7K1W2|A0A0J7K1W2_LASNI Ester hydrolase c11orf54-like protein OS=Lasius niger GN=RF55_18048 PE=4 SV=1 +----SINTATLKDVRDVL-YNLREYFNKFEIDVGSCPPLTARPYNFDFNGLSGLNILEQNFPMEKMT-NI-------------------------------------------------------------TPLDESdpvrpiRLHTK--------------YKFFTEDRPGMVLEMYARGRKTNQSIITLMQNILHRRFSh--KMGLGGILIVKGGQLLQYNPK-----FTCEATYH------HIKCDSEITCSGAIVNDPVQilghhdglLmttnrymfDI--------HSEHGNGFFVNDITPKETEYYGIFNVADAVCRW------------ +>tr|A0A0J7K5S5|A0A0J7K5S5_LASNI Ester hydrolase c11orf54-like protein OS=Lasius niger GN=RF55_15835 PE=4 SV=1 +----SWNSATLKDVRDVL-YKLHDYFDHFEIALVACPCLKKSPYNLDFAGLSGNMYIEELKSPVN---ML-------------------------------------------------------------HPNITVpqagpiPFRSN--------------RNFYSDGKPGMVLKIRARGRRTDHSIITLIQSILHKRFSy--KMGLGGVLLMIGGRVARHIPET----FPLVLSER------YLDCNPAVSAICTIVNNPVLflyqeddlPedgdlyylDTnnsptviqn---YESHCFFGNEHGLFVNDVTPKDTEYVGYFNVAEKVYRV------------ +>tr|A0A1A9UK18|A0A1A9UK18_GLOAU Uncharacterized protein OS=Glossina austeni PE=4 SV=1 +------------------------------------KSLHKPPLEELQNGLGGCPTLLELGGAPYLLPKVQKDKLYDIKAICRKSMVG----AGAGPYPLRNTNCEGIFNLSISAQDE---IKNGSYTAKITGLQEDCLLEPIPD--TETRCALLLNLYVCRGEPGPVLKITCKKRTGHMNFIECIRKGLYEKYEDKCV------------------------------------------------------------------------------------------------------------------ +>tr|A0A0C2GJL4|A0A0C2GJL4_9BILA Uncharacterized protein (Fragment) OS=Ancylostoma duodenale GN=ANCDUO_10715 PE=4 SV=1 +------------------------------------KNLTAAPFRMTSNGFGRNLVIAEVGGMGNLYPELHKEKQYDIQEICEKCGAPKAFVFGPGACPSRVVGAGEL-----VADAN---LSENKVSSKVTTLVKDHFLKYKTKIINSTKFS-LMGNLVVSEQPGP---SECSERTGEDSLPGCIRKGMGEHYGQ--------------------------------------------------------------------------------------------------------------------- +>tr|A0A0J7L9H0|A0A0J7L9H0_LASNI Ester hydrolase c11orf54-like protein OS=Lasius niger GN=RF55_650 PE=4 SV=1 +--ETDLFVPEAKGLARTLQNGLRKHFAEATVEWVDCSDLTQEPFNLAAP---------------AFL----------------------------------------------------------------DEDTGMCALESITNSNPDYY--PYGNLFISEGQPGQVLKVQAKKRIN-MGFLSALQNALYYEYSfNnprQLVGLGGTFVMKNGRAKHHVLPYSWN-ARLKAAADIHNWLHYFVLDAPLIAVGTLVSSS---------------------------------------------------------- +>tr|A0A068XJ06|A0A068XJ06_HYMMI Ester hydrolase C11orf54 protein OS=Hymenolepis microstoma GN=HmN_000316500 PE=4 SV=1 +---------------------------------------------------------------------------------AQASRQVQGMIIGGGLGPFQTYNRPCEVAADITFTSR-GLESNNSLV---GFADKGEELPEF-RSASNSYIATMGQFFVTEAKPGKVIQIEAKGRNGGQNIFDMIQGALYEKYRGeeLPMGVGGVFFLNDSSAQVSLLN-AIPGESYHTYPCVRSYKTPFSINGPIVGAGTIISHDPtslGYMMKSFYCWNTART-LMGQFEYDNNPANAHFQIYLTVATQIYRHDRPV-------- +>tr|A0A0R3SGI5|A0A0R3SGI5_HYMDI Uncharacterized protein OS=Hymenolepis diminuta PE=4 SV=1 +---------------------------------------------------------------------------------AQASRLVQGMIIGGGLGPFQTYNRPCEVAADITFTTR-GLESNHSLV---GFGDVESESSKF-CRATNSYIASMGQFFVTEAKPGKVIQIEAKDRRGGQNIFDMIQRALYEEYNGeeLPMGVGGVFCLQNSSAKVSLLN-EVPSETYHTFPCVRKYKTSFSIEGPIIGAGTIVSHDPttlGYMMKSFYCWNTART-LMGQFEEDDDPANACFQIYLTVATQIYRHDKPV-------- +>tr|A0A0R3X4K6|A0A0R3X4K6_HYDTA Uncharacterized protein OS=Hydatigena taeniaeformis PE=4 SV=1 +---------------------------------------------------------------------------------------------------------LST---EITFSTR-GLQCNRSLI---GFYSKECGSPTS-ERASNTLLSSVGQIFITEAMPGKVIEIVAHKRIGGPSIFDLIQASLYDKFSKqdLPMALGCVFYLQNSGVQASVLC-ELPQEPYHTFPCLKKYQASFTIDGPIIGVGTVLSHDPkkmGFSMSTFNCWNASRL-LTGQFENDVCPEKATYTVYLTPAKKLYRQDKPV-------- +>tr|A0A0R3VSV7|A0A0R3VSV7_TAEAS Uncharacterized protein OS=Taenia asiatica PE=4 SV=1 +--------------------------------------------------------------------------------------------MRAGKE------AINTERSKMQWQR--AEGIIGKSM---ATDHAVCGSPAS-ERASNTLISSMGQLFITEAMPGKVIEIVAHRRIGEPSIFDLIQASLYNKFSKqeLPMALGCVFYLQNSGALANVLC-EIPQEPYHTFPCLKKYQASFNIDGPVIGVGTVLSHDPkkmGFSMASFHCWNASRL-LTGHFENDVCPEKATYTVYLTPAKKLYRQDKPV-------- +>tr|A0A183SVC8|A0A183SVC8_SCHSO Uncharacterized protein OS=Schistocephalus solidus PE=4 SV=1 +---------------------------------------------------------------------------------ANACKVRAGEILGGGTGPYPT-----------------------------------------------------------TGHPCEVIEVIAKRRLCEGSIGKFLHQALQSRYGRgdEPMALGGVFLLEGSGAKYHVLS-ELPNEPYHTFPDLKSYLKCFEMKAPIIGMGTVLSHDPvrlpfififlpsgrvplkegslkqndlGLHMHSFHIYNVERN-VAGHLETDTDPEAASYRIFLHPASHICRMDKPV-------- +>tr|A0A026W8V3|A0A026W8V3_CERBI Ester hydrolase C11orf54 OS=Cerapachys biroi GN=X777_08556 PE=4 SV=1 +------------------THALSMNFSEVAVECIDCPDLRQY--RLVAPGLCGNPAILEIGSLSYLFPQARLDKKYYFKNILRQLNLTsqDNFIIGAGNHSYPPNYDHSElyanFMLS------RASPTDGSMGV-QNASnalwFGGKEFEelKWRYVCEtNPMCAIQGNFFVSQGEPGNIFRINAVNRTGPLDFVSSIQMSLKRMrqkTDPHLIGLGGIFTTSDDNaILHHGIPGKRNATEFYTMNQVQQWLKYKTITEPIIAVGTIMSE----------------------------------------------------------- +>tr|A0A158NTI0|A0A158NTI0_ATTCE Uncharacterized protein OS=Atta cephalotes PE=4 SV=1 +----DLYVPEQTELATVLQNELSTDFEEVTVEWVDCPDLTQEPFNLATPGLCGDTALLDXGGISNLFPFPLKDKIYFQNILQKLDRtQSDNLIIEGGLCTKQSnellveLIMNASFSPAANGTM---TVKNKSSFASIEITQKKKYFVLKSLTDTNPYCNIYGNFFVSKGLREQVLKVHAKHRTGR-DFIVALQHAI--------------------------------------------------------------------------------------------------------------------------- +>tr|A0A0D6LKB6|A0A0D6LKB6_9BILA Uncharacterized protein OS=Ancylostoma ceylanicum GN=ANCCEY_08542 PE=4 SV=1 +-------KPSNHELRSVIEAALWKNFKNVQVEVEKCPDLTAAPFHMTSPGFGRNLVIAEVGGWGNLFPNLHKEKLYDI-------KLD------HYTSPYKTLFVNSTK------------------F------------------------VLMGNLAiTPEPGPAEVVHIKCSQRTGKDSFPGCIRKHMAQHYGQ--------------------------------------------------------------------------------------------------------------------- +>tr|A0A026VSB4|A0A026VSB4_OOCBI Ester hydrolase C11orf54-like protein (Fragment) OS=Ooceraea biroi GN=X777_00054 PE=4 SV=1 +----KLHLPDPNRVIDILDHGLRLNFEEVTVDWMDCPDLRK--FGLAAPGLCGNPVLLELGNLSYLSPWPRQNKIYSFKHILSQLDLLGqdNFIIGAGK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ +>tr|A0A026W8V3|A0A026W8V3_CERBI Ester hydrolase C11orf54 OS=Cerapachys biroi GN=X777_08556 PE=4 SV=1 +---IDLHVPDPTTITNVLTHALSMNFSEVAVECIDCPDLRQY--RLVAPGLCGNPAILEIGSLSYLFPQPRLDKKYYFKNILRQLNLTsqDNFIIGAGNHSY---------------------PPN--Y-D---------------------HSELYANFMFSPTRPAGSMDVQNKRITVWstMENNNCMHEVCKINPLCAIQGLGGIFATFHESNLYHIMPAFSKATDLYTMNQIQQWLKYS-------------------------------------------------------------------------- +>tr|A0A1I7T578|A0A1I7T578_9PELO Uncharacterized protein OS=Caenorhabditis tropicalis PE=4 SV=1 +-----------QETFQVFQTALDNNFEAVQVDIVECPDLSKPPFNQKSSGFGQNLKIAEVGGPGNLYPGFHIDHQFDISTIGKVCEHPEASIFGPGAGPWPVVGQNCEMVAD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|A0A151XCV3|A0A151XCV3_9HYME Uncharacterized protein OS=Trachymyrmex zeteki GN=ALC60_02839 PE=4 SV=1 +--EIPLLTPTISEIAEVLHNEMQPLFHEVNVDIASCPCLTVAPYNLAGVGLCGNTSVIMYYPE-NSEGW--NHRTKNIRDMLT-ASCRDSFVIGATYAT-------KPSMP---------------YYGHLIMN---------------------ATYRAPNGI-------RN---ESRIISA------------NK--ALGGVLRIKNGRVACNVMWDDY----------EEPMPRFYDFIqqqqCPeidvesdMVAVGTMLSEKPELltnqeqryGLNLykrSEFHCFSNIETGGQFISDTTPDTTEYEGYFNVAEQI--------------- +>tr|A0A151J8Z9|A0A151J8Z9_9HYME Ester hydrolase C11orf54 like protein OS=Trachymyrmex cornetzi GN=ALC57_06156 PE=4 SV=1 +--IYPMMPPNILEIADVLQNGMQPLFHDVRVDIASCPDLTTAPYNLAGVGLGGNTSLVEFLRHDVHTPW--KHRTRDILKVFT-GSIRDSFIIGSTFAT-------KPTMP---------------YYGHLIMN---------------------AMYTAPMGI-------RN---ESRLIFA------------ELRngqtriekltdpnqmiytckgnffisegregpvirvrakgrkksdtdiitsmqtvlyehygrnwktVALGGVLKMTNGRVACNLMWDEY----------QEPILSFPDFVraqqCTeiclesdMVAVGTIFNRQPLLfnqeqryDLNLynrSEFHCFNNYGAGGQFISDTTPDTTEYEGYFNVAENI--------------- +>tr|A0A151JUE1|A0A151JUE1_9HYME Uncharacterized protein OS=Trachymyrmex septentrionalis GN=ALC56_09563 PE=4 SV=1 +--TFPTNPPTLSEIAEVLQNGMQPLFQQLNVDIASCPRLTTAPYNLAGVGLGGNTTIIEFLHINDNVPW--NHKTRDIREILT-SSCRDSFIIGSSYAS-------KPHMP---------------RYGHLIMN---------------------ATYRAPMDL-------KN---ESRLIFA------------ERRneqttiekltdpnkmiatqgnmfvsEALGGVLKMKYGSVACNLMWDDY----------QEPLLPFYEFIrrqqCTeihlesdMVAVGTIVNTEPRLwaqeqryNVNLynrFAFHCFSDDGVGGQFVSDTTPDTTEYEGYFNVAENI--------------- +>tr|A0A195EDN7|A0A195EDN7_9HYME Uncharacterized protein OS=Trachymyrmex cornetzi GN=ALC57_04705 PE=4 SV=1 +--IHPLTPLNLSEIAEVLQNGMQSLFHDVRVDITRCPYLTTAPYNLAGVGLCGNTAVVEFLRHDQNVPW--NRRTKDIQQLLT-CSIRDSFIIGSTYAT-------KPNMP---------------YYGHLIMN---------------------ATYKAPMGI-------RN---ESRLIFA------------ELRngqtriekltepnqmiytnkgiffvsEALGGVLKMTNGSVACNLMWDEY----------QEPISPFPDFVreqqCPeiclesdMVAVGTILNNEPKLteeqryGIVSylsQL--CGD-------------------------------------------- +>tr|A0A151JUC6|A0A151JUC6_9HYME Ester hydrolase C11orf54 like protein OS=Trachymyrmex septentrionalis GN=ALC56_09908 PE=4 SV=1 +--TFPTNPPTLSEIAEVLQNGMQPLFQQLTVDIANCPCLTKPPYNLAGVGLGGNTSIIDFVHYSEILPW--YRRRVNIQEILT-SSCPDSFVIGSSYAT-------KPHMP---------------HYGHLIMN---------------------ATYRAPMDL-------KN---ESRLIFA------------ERRngqttiekltdpnqmkatqgimfvsEALGGVLKMKYGSVACNLMWDDY----------QEPLLPFYEFIkrqqCPeihlesdMVAVGTIINNEPGLwtqeqryNIVSylsRLCGQ---------------------------------------------- +>tr|A0A0N5AJK7|A0A0N5AJK7_9BILA Uncharacterized protein OS=Syphacia muris PE=4 SV=1 +-----TLVPPLNDFGKAIQEYMKKNFSGVFVEVVpECPDIG---------------------GNAHLCPVPRPDIYYKL-------EFSKGFMFGPGAGPCYVIGVNSEMVAD---ASFSEAPENVAI----------------------------KVGFTS-----------GKKEVGCKMMIT-----------DKPeFCILGNLAIRKIRAF-----GRLSN--------VALTEQYFELDSPVVCTTVIHIRDVnQCNLRLDYTHCYTDSNAG-QFYGDTEPERMEYVDYFVIAEAVYRIDK---------- +>tr|A0A1E1W1F6|A0A1E1W1F6_PECGO Uncharacterized protein (Fragment) OS=Pectinophora gossypiella GN=g.16499 PE=4 SV=1 +--EKPLHVPPLQEIADVLSGGLPATFESVSAAVVECPDLTQPPYNLTSPGLSGDAKLVEIGGPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|A0A183PEH6|A0A183PEH6_9TREM Uncharacterized protein OS=Schistosoma mattheei PE=4 SV=1 +-------------------------------------------------WLSGKTIICDVGSFDYLLPVPKKDrvcivlsdllaKHYDLLDVFRNAGVAAGAVIGAGAGPFFLTGSNSEMV--INISSESGVVKNGSLFGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|W2TK28|W2TK28_NECAM Uncharacterized protein OS=Necator americanus GN=NECAME_17819 PE=4 SV=1 +-------------------------------STENIPDLTAAPFHMTSNGFGREFSVAAVGSLDNLYPCPNREKMYDLKDVCKKCEAPNAFVFGAGGCPPKVAGKNGELVA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|S4PZU3|S4PZU3_9NEOP Ester hydrolase-like protein (Fragment) OS=Pararge aegeria PE=4 SV=1 +-----LYTPPLEEIVDVLSRRLPATFEHVEVSAEDCPDLTQQPFNLSAPGLAGDAK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|A0A151JTQ9|A0A151JTQ9_9HYME Ester hydrolase C11orf54 like protein (Fragment) OS=Trachymyrmex septentrionalis GN=ALC56_11238 PE=4 SV=1 +---------------QLLQNGMQPLFQQVTVDIASCPCLTKPPYNLAGVGLCGNTTIIDLVYRSEIIPW-NRRKV-DIRKILRSS-CRDSFVIGSSYATkprmphYGHLIMNATYRAPMD-------IKNESRLIFAERRNGQTTIEKLTDPN--QMKATQGIMFVSEGRAGLVIRVRAKGRkTINTDIITSMQTILFERYRrNENKDIGGVLKMKYGSVACNLMWDDYQ------------------------------------------------------------------------------------------- +>tr|A0A1I8J519|A0A1I8J519_9PLAT Uncharacterized protein OS=Macrostomum lignano PE=3 SV=1 +---FRLHRPDLAAVADCLDRACRDAFEDASVELIDsCPDLSEPPFCLAGRGICGGGG-------ENSGP-VEQ-RRYDLRNLLKATGHLDGLIIGAGAASSTRFGRNAELVAN------LGPLGNGCRVASLR-ADGEDNGTENLANCrlsrPDFAEAgLMVDSLCSSGQtDGPVLRLRASRW----------------------------------------------------------------------------------------------------------------------------------------- +>tr|F4X816|F4X816_ACREC Ester hydrolase C11orf54-like protein (Fragment) OS=Acromyrmex echinatior GN=G5I_14552 PE=4 SV=1 +-RVYPLEIPTLLEIAEVLQNGMQPLFQRVNVDIASCPNLSTAPYNLAGVGLGGYTSIVELFLLEPNVPWNQR--TRDFQEIFTTS-CRDAFVIGTSYATKPSMPYYGHLIMNATYRAP-MDIRNESRLIFAERGNGQTRIEKLTD-PNQMKYTNKGIFFVSEGRGGHVIRVRAKGRKT---INTDIITVLYEKYENDNKFVGGVLKMTNGSVACNLMWDDY-EEPLGSFDDIIRRQQCaeIHLESDMIAIGTIINDKPVL------------------------------------------------------- +>tr|A0A151JZ30|A0A151JZ30_9HYME Ester hydrolase C11orf54 like protein OS=Trachymyrmex septentrionalis GN=ALC56_03953 PE=4 SV=1 +--TIPANPPTLSEIAEVLQNGMQPLFQQLNVDIASCPRLTTAPYNLAGVGLGGNTSIIEYLHRNDNAPW--NHITWDIREILTTS-CRDSFVIGSSYAAKPHMPHYGHLIMNATYRapmdlkNESrlifterrngqttiekltdpnqmiaiqgnmfvsegragrvirvrakgrkfintdiitsmqmilyeryrrcenkyvesdmvavgtivnteprlwaqeqrynVLimnatyrapmdLKNESRLIFAERRNGQTTIEKLTD--PNQMKATQGIMFVSEGRAGLVIRVRAKGRKTiNTDIITSMQTILYERYKRnENKVVDGVLKMKYGSVACNLMWDDYQ-EPV---------LPFYEFikrqqcpeiylESDMVAVGTIINYEPKL------------------------------------------------------- +>tr|F4X033|F4X033_ACREC Putative uncharacterized protein OS=Acromyrmex echinatior GN=G5I_11615 PE=4 SV=1 +--VYPLVPLTLLEVVEVLQNGMQPLFHDVKVDIARCPYLTTAPYNLAGIGLGGNTSVVEFVH--DGIPW--NYKTRNIQDVLTTS-CRNSFIIGSTYATKPHMPYYGHLIMNATYRapmdirNESrlifaerrngqtriekltdpnqmiytnkgsffvsealggvlkitngivacnlmwddyeepmlesfhdfirrqqcpeihlqsdmiavgtiindklkfitaerrydILimnatyrapidIKNESRLIFIERRNRQTKIEKLTD--PNQMIYtNKGSFFVSEGREGLVIRVCAKGRKTiNTDIITSMQMVLYEKYCRnEDKVFGGILKMTNGSVACNLLWDHYE-EPI---------LEsFHDFirrqqcpeiylESDMIAVGTIINDKPQL------------------------------------------------------- +>tr|A0A195CWL7|A0A195CWL7_9HYME Uncharacterized protein OS=Cyphomyrmex costatus GN=ALC62_04540 PE=4 SV=1 +--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTYGQVACNVMYDEYPEMlPFYDFFL-QQQCSEINLESDMIAVGVIFNSFPVrmteqprygVSIyNRNEFHCFSDFGAGGQFINDISPDTTEYEGYFNVAEKLIIP------------ +>tr|A0A151WZ88|A0A151WZ88_9HYME Ester hydrolase C11orf54 like protein OS=Trachymyrmex zeteki GN=ALC60_07638 PE=4 SV=1 +--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKNGRVACNVMWDEYEEPmPlFDDFVK-QLQCPEIDLESDMVAVGTILNEKPQlltdqeqrygLNLyNRSEFHCFSNYEAGGQFISDTTPDTTEYEGYFNVAEQMNLI------------ +>tr|A0A195CV39|A0A195CV39_9HYME Uncharacterized protein OS=Cyphomyrmex costatus GN=ALC62_04539 PE=4 SV=1 +--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRYGQVACNVMCDEYPGRiLsFNNFFL-QQQCIEITLESDLIAVGVIFNNIPLpladqeqrygINLyNRSEFHCFSNYGAGGQFISDTTPNTTEYEGYFNVAKKLIDV------------ +>tr|A0A151WZT1|A0A151WZT1_9HYME Uncharacterized protein OS=Trachymyrmex zeteki GN=ALC60_07639 PE=4 SV=1 +--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RGGVLRMRNGRVACNVMWDEY-EEPMPPFYDFVKQLQCPeiDLESDMVAVGTILNDKPEllpqeqrygLNLyKRSEFHCFSNSEAGGQFISDTTPDTTEYEGYFNIAKKLN-------------- +>tr|A0A195ET10|A0A195ET10_9HYME Uncharacterized protein (Fragment) OS=Trachymyrmex septentrionalis GN=ALC56_14249 PE=4 SV=1 +----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LFVSEGGVLKMKYGSVACNLMWDDYQEPmlPFDDFIRGQQCS-EIYLESDMIAVGAIMNDKPELLtqeqrygtnvYNRSEFHCFSNYGAGGQFINDTTPDMTEYEGYFNVAEKY--------------- +>tr|A0A183X9N9|A0A183X9N9_TRIRE Uncharacterized protein OS=Trichobilharzia regenti PE=4 SV=1 +--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLVIWLKLIVLTSLIIFcfilinlFSVLSSTQHRLGLRLEHFHCFNQdQTNCGHCHFDTHGPTVAYRAYFSLAEKLIRIDQPNK------- +>tr|A0A195CVI4|A0A195CVI4_9HYME Pro-resilin OS=Cyphomyrmex costatus GN=ALC62_04538 PE=4 SV=1 +-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEGGVLRMRYGQVACNVMWDEYPNGMLQ----FGNFyfeQRCIEmtLESDLIAVGVIVNNAPypfsaqryGINLYnKCEFHCFSNYGSGGQFISDTTPDTTEYEGYFNVVENLIHVPNVN-------- +>tr|A0A151JPR3|A0A151JPR3_9HYME Uncharacterized protein OS=Trachymyrmex cornetzi GN=ALC57_01503 PE=4 SV=1 +-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FISEGGVLKMTNGRVGCNLIWDEYRDRIL-PFPDFVKAQQCteICLESDMVAVGTIINHQPLqfnqeqrygVNLYdRSEFHCFNNYGAGGQFITDTTPDTTEYEGYFNVAENS--------------- +>tr|F4WZJ6|F4WZJ6_ACREC Putative uncharacterized protein OS=Acromyrmex echinatior GN=G5I_11421 PE=4 SV=1 +-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FVSEGGVLKMTNGIVACNLMWDDYEEPMLESFHDFIRRQQCpeIHLQSDMIAVGTIINDKLKfitaerrydVDLYeyRSEFQCFSNYEAGGQFISDTTPDITEYEGYFNIAKNM--------------- +>tr|F4W740|F4W740_ACREC Putative uncharacterized protein OS=Acromyrmex echinatior GN=G5I_01248 PE=4 SV=1 +-RVYPLASPTLLEIAEVLQNGMQSLFQRLNVDIASCPHLSTAPYNLIGVGLCGNTSIVELYPFQENVPWSQRT--RDFREIFTTSCC-DSFVIGTSYAT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|A0A026VU98|A0A026VU98_CERBI Uncharacterized protein OS=Cerapachys biroi GN=X777_00165 PE=4 SV=1 +------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FRVVNIPTLHHIMP-AFgSKTNLCTTTRGYKWLTYSKVVEPLTAVGTIMSEGGYynnicsnyeynTYITKSHFHSYNRsTEEGGHYYGDYDPTFVssnsfgSYIGYFSFADKLYVMDPPDRTHNI--- +>tr|A0A0C2CLF8|A0A0C2CLF8_9BILA Uncharacterized protein (Fragment) OS=Ancylostoma duodenale GN=ANCDUO_19282 PE=4 SV=1 +--------------------------------------LTAAPFRMTSNGFGRNLVIAE--------------------EICEKCGAPKAFVFGPGACPSRVVGA-GELVADANLSEN---IVT-SKVTTLVK---DHILKYKTKMINSTKFSLMGNLVVSEL-PGP-SEVDMTSRLDQVDFV---------------------------------------------------------------------------------------------------------------------------------- +>tr|A0A151JT76|A0A151JT76_9HYME Uncharacterized protein OS=Trachymyrmex septentrionalis GN=ALC56_13780 PE=4 SV=1 +----PKNPPALSEIAEVLQNGMQPLFQQVTVDIASCPCLTKPPYNLAGVGLGGNTSIIEFLRHNEDAPWNHIT--RDIRVILSSS-CRDSFIIGSSYASKP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|A0A026W8I3|A0A026W8I3_CERBI Uncharacterized protein OS=Cerapachys biroi GN=X777_08555 PE=4 SV=1 +--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GDpRMIGLGGIIFLNDNIpTLHHVTPSCYSLSNLHTMNQVQEWLQYKTTLEPVTAIGTIMSEGGYyknLcpsstenpYITKSHFHSRMPSGSGGHLYTDFVdnnYSDAYYVGFFSFAEKLYCVDPPSHQD----- +>tr|A0A183B0J5|A0A183B0J5_9TREM Uncharacterized protein OS=Echinostoma caproni PE=4 SV=1 +--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSLFSQNQQWKLRLEHFHCFNRdRTKAGHCHFDTDGTAASYRAYLVPGRKLLRVDKPQ-------- +>tr|F4WYH8|F4WYH8_ACREC Putative uncharacterized protein OS=Acromyrmex echinatior GN=G5I_11031 PE=4 SV=1 +--------------------------------------------------------------------------------------------------------------------------RNESRLIFAERGNGQTRIEKLTD-PNQMKFTNNGIFFVSEGRTGLVIRVRAKGRKTiNTDIITSMQTVLYEKYKRnEDKVVGGVLKMTNGSVACNLMWDDY-EEPLESFGDIIRSQQCaeIHLESDMIAVGIITNDMPQL------------------------------------------------------- +>tr|A0A183QJR6|A0A183QJR6_9TREM Uncharacterized protein OS=Schistosoma rodhaini PE=4 SV=1 +---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QEHFHCFNQdQTNCGHCHFDTHGPTVSYRGYFAIAEHLLRIDQPSK------- +>tr|A0A151WZ90|A0A151WZ90_9HYME Uncharacterized protein OS=Trachymyrmex zeteki GN=ALC60_07640 PE=4 SV=1 +--RIPLSAPIISEIAEVLQNGMQPLFHEVNVDVASCPCLTGAPYNLAGVGLCGNTSVMKYRRFitENLEE--RNHTTRNIRDILTTSC-HDSFIIGSTYA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|A0A151JY44|A0A151JY44_9HYME Sterol O-acyltransferase 1 OS=Trachymyrmex septentrionalis GN=ALC56_04665 PE=4 SV=1 +-RQYSLNEPTLSKIAEVLQNGMQPLFQQLNV-IASCPCLTTAPYNLAGVGLGGNTSIIEFLYLNDNVPWNRR--TRDIREILTTS-CNDSFVIGSSYATKPHI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ +>tr|A0A0C2GEL8|A0A0C2GEL8_9BILA Uncharacterized protein OS=Ancylostoma duodenale GN=ANCDUO_14299 PE=4 SV=1 +----------------------------------------------------------------------------RAQEVCNTCGAPKAFVFGPGGCPPSAVGVNGELVADANLSENK--VA--SKVT-IQL-D-NYTTPYKTLLVNSTKFVLMGNLAITPePGPAEV------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|A0A0C2G9J1|A0A0C2G9J1_9BILA Uncharacterized protein OS=Ancylostoma duodenale GN=ANCDUO_14297 PE=4 SV=1 +-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ETFGPALRTMLLKRSVAfSCVSLAGIFLLLRGKADVHIAP-DFPDKPFKSMEE---------------------------------------------------------------------------------- +>tr|A0A183RET9|A0A183RET9_9TREM Uncharacterized protein OS=Schistosoma rodhaini PE=4 SV=1 +------------------------------------------------------------------------------------------------------------------ISSENGVVKNGSLFGSYDKENNKPLLT----KADNTKFALLGQMFMCEGKPGPVSEMN--------------------------------------------------------------------------------------------------------------------------------------------- +>tr|A0A026W9R7|A0A026W9R7_CERBI Uncharacterized protein OS=Cerapachys biroi GN=X777_08554 PE=4 SV=1 +----------------------------------------------------------------------------------------DNFIIGAGKHSAPPYYNHGQLFANLMFSRA--NPTNRSI-GLTNKNTASWSFmENitYMQNTweDNPTCSTQGNFFLSEGKPGKVLRVVF-------------------------------------------------------------------------------------------------------------------------------------------- +>tr|A0A151JY71|A0A151JY71_9HYME Uncharacterized protein OS=Trachymyrmex septentrionalis GN=ALC56_04664 PE=4 SV=1 +----HLTSSTFAEIAEnmFLQNGMQSLFHDVKVDIARCPYLTTAPYNLSG--------------VEN---W--NHRTCNIQDVITIS-CHDFFIIGS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- +>tr|A0A183CMN1|A0A183CMN1_GLOPA Uncharacterized protein OS=Globodera pallida PE=4 SV=1 +----ELIKPNVAELIPELRSVLRPAFSSVHCDLATCPSLNQAPFNLPVQGPGPNFTF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- diff --git a/esm/source/examples/data/hhblits_uniclust_2017_10_5ahw_1_A.a3m b/esm/source/examples/data/hhblits_uniclust_2017_10_5ahw_1_A.a3m new file mode 100644 index 0000000000000000000000000000000000000000..ae44844cba3e6df2e94f33edeaff6a82d22c281b --- /dev/null +++ b/esm/source/examples/data/hhblits_uniclust_2017_10_5ahw_1_A.a3m @@ -0,0 +1,3262 @@ +>5ahw_1_A +SAYQTVVVGTDGSDSSLRAVDRAGQIAAASNAKLIIATAYFPAPIYAILREANDRAKAAGATDIEERPVVGAPVDALVELADEVKADLLVVGNVGLSTIAGRLLGSVPANVARRSKTDVLIVHTS +>tr|A0A191HSK0|A0A191HSK0_9FIRM Uncharacterized protein OS=endosymbiont 'TC1' of Trimyema compressum GN=AZF37_00820 PE=4 SV=1 +--YKNIVVGVDTSPQAYEVFKKAMDVAKTEGSTLHIVSAVPFIPDTdvinttielgvtpsvrqeqefaveikerrAILETYVA-eAKEYGV-eTVTLTIESDHSKNLILTELEDFEGALIVIGASTKTPLKRFMIGSTAKYLATHAPCNILIVKSY +>tr|A0A1G0MC00|A0A1G0MC00_9DELT Universal stress protein OS=Geobacteraceae bacterium GWC2_55_20 GN=A2X82_10850 PE=4 SV=1 +--RKKILVAIDGSPQSDKAAEEAVRLAAGNQSQFKSPVFALLVLPNaptstytdfvpsapmtetekwddlrrrifFVVEKCAA---EHNIPl-EMIVE-YGDPAEKMISFAKREGIDVIVIGSSSKGFIQRRIKGSISHKIASSAPCSVYIVRG- +>tr|A0A1Y4FWL9|A0A1Y4FWL9_9ACTN Uncharacterized protein OS=Gordonibacter sp. An230 GN=B5F40_12895 PE=4 SV=1 +-GGRRVFAALDETPAREAVARAALELAEDSGGHLLFGHIADALsreaamtdlealrrsaeerlehHLADVLKAARGSRRLAS---FELIVEAGPAAQTVvRSLMLPFEPDLVVCGRCREARLHCRIATGVGAALLRAAPCSVLIVE-- +>tr|A0A0X9VCG1|A0A0X9VCG1_9BACL Universal stress family protein OS=Kurthia sp. 11kri321 GN=ASO14_1320 PE=3 SV=1 +--TKKVVVAYNDTDLSNDVLDYVHEILEMHaEIELNIVYAYEHPLE-npspfqrnyddgapemlayaeQIIQKAKNRF---VDlpNHVEGFVYDTGPAAAILSHAHDHHADLIVIGNRGTRGLREL-VSSVSRTIQTKSHIPVLTF--- +>tr|A0A0C5BVJ8|A0A0C5BVJ8_9ARCH Universal stress family protein OS=Candidatus Nitrosopumilus piranensis GN=NPIRD3C_1069 PE=4 SV=1 +--TKRIMVCLDGSKNSLRGLDKAISFAKQSDTIIVGVH--SDtsfsafsavrapilP-mkkwkqkAKALMNIAKKKVEKNKIEFEGIVIAGHTSGIDLTtfANNPANKIDQIVIGSRGMGFPKELFFGSTSNFVLHKAKAPVTIVK-- +>tr|A0A0F2Q180|A0A0F2Q180_9CLOT Uncharacterized protein OS=Clostridiaceae bacterium BRH_c20a GN=VR72_21865 PE=3 SV=1 +--FKKILFPTSGSPVSEKIALTIVNLISDTKN-AEITIVYVLQVTpfhrtvsYqledkgidsskLaledikdILEKATKVFRENNI-PYTi-rV-ELGEPVEMILKIAEe-TKSDLMVVGFHGHSTLSDYLFKGNITNeLIDKTNCPILVVK-- +>tr|A0A0P7XFL6|A0A0P7XFL6_9BACT UspA family universal stress protein OS=Bacteroidetes bacterium HLUCCA01 GN=HLUCCA01_06575 PE=4 SV=1 +-LPQNWLIATDGSKYATMSVEYAARLYaCMSpRPNVLLLNIIPdpRRKgavdheteagSRRVLAESRQFFLDlagSDE-TVSTMVGIGEPRQIIVETVKANKIDHLIMGGADYqWRITDLLSGGVTNYIIEHVSCVITLIK-- +>tr|A0A127QJP0|A0A127QJP0_9BURK Universal stress family protein OS=Collimonas arenae GN=CAter282_2255 PE=3 SV=1 +-MLKRILVAIDGSELGNNALRHGCALAKEQGCEIRALYINvdpflafpllgvvyFQrEQMLQAaaeqaagvRAVAL-kVFDAFELRgdvQILDLQEKGkRVADLIREVSSRWNASVVVMGSHGLQGMQRLMLGSVAEHFLRIADCPVLIMKS- +>tr|R8DTA9|R8DTA9_BACCE Uncharacterized protein OS=Bacillus cereus VD133 GN=IIU_05957 PE=3 SV=1 +---MNIVVPMDLSSHAQLALKEATQLFKGANFII--LIVVdiidepenvfDwQGNMY--ESkihlfkEINAFIE--RqkemfP-NAsIEFdVCSGEAKHEIIHYARQhNEIDCVVIGATSKRALSKVILGSTTDYVVKHINHNILVVR-- +>tr|A0A1E8D0Z5|A0A1E8D0Z5_9MICO Uncharacterized protein OS=Humibacillus sp. DSM 29435 GN=BA895_00715 PE=3 SV=1 +--KNCVIVAVDDSSASRAAHRWAASYARATATDLCAVHVLDWPIGLVGHpgeprtrlyvparhvapsyRRRLHRVLDdsdstvDeatgpaadsetdiDScAASSLHFAQGPVGEVLVRLS--THATLLVIGTREPLrDGHRLVTGSASHYCVSHATCPVVTVPE- +>tr|A0A1F2QI41|A0A1F2QI41_9BACT Uncharacterized protein OS=Acidobacteria bacterium RIFCSPHIGHO2_01_FULL_67_28 GN=A2620_02860 PE=4 SV=1 +-APKKILVSLKQASDAGELINLA-RHVAAPGARITALHVVEVPAATPlgaedraldapaeAVERAVKKlark--HRGVKIAVRLLRARHAGKAIADELKEGKFDLAVMSYHHKRSLAELLLGTTASYLAKHAPCRLLMSVP- +>tr|D3BL96|D3BL96_POLPA Uncharacterized protein OS=Polysphondylium pallidum GN=PPL_09328 PE=4 SV=1 +---MKYLIAIDGSDHAHNAFMKAVALYKPGDEI-YTLIaidlVHFMMAApklaeetttladmKekmlangnKLSGQYAELADEHNIAKYKTLLLEGNPRELIVKeVA-ERKIDILIIGQVGLINNPNISMGSTSTYCIRNCQCDVLLFWS- +>tr|M5J4E9|M5J4E9_9LACO Universal stress protein OS=Lactobacillus saerimneri 30a GN=D271_07799 PE=3 SV=1 +ERYQNILVEIDGSKQSYEAFRRALEIAQRDQAKVYAVIiinnslSLLRTVAinvaydin-iqtnaqSNLDRCRVIAHNTGFQDLHTMILEGRSKATMLRdFIADHDIDLFLAGSKRKQFLDLLFTDSIATKVANFTNCDVSIVK-- +>tr|A0A1H6IYN5|A0A1H6IYN5_9MYCO Universal stress protein family protein OS=Mycobacterium rutilum GN=SAMN04489835_1231 PE=4 SV=1 +---RLGVVVGIGTGVSTTATQWATHHAATHRIPLTLVTTGTTASQtiktgwdslpl------------------VRAIAVDAPLEHTLIQLSAQ--AEIVALGNDCPSTH------RTLSALVRRGHSNVASIPE- +>tr|A0A1G9JQQ8|A0A1G9JQQ8_9GAMM Nucleotide-binding universal stress protein, UspA family OS=Dyella jiangningensis GN=SAMN04487785_11934 PE=3 SV=1 +--FKRILLPIDGSEQSLRAASTGIALAAQGEHQAFGLEVLCPTPSItlvadAIvhdssnhtdrairkahddLAEVAGMARDAEVAFADIYVFDQRPYTAIIAAAHSAGCDLIVIGAGEYARGRGAQLSREVSLLVNSAEMPVLVCP-- +>tr|D6SKL4|D6SKL4_9DELT UspA domain protein OS=Desulfonatronospira thiodismutans ASO3-1 GN=Dthio_PD2634 PE=4 SV=1 +----NLLVPHDGSEFANKTMDKAIDFCRKLGGGkVYSVVvvpdLciSFVgrdecNLLestlqkegNEIKNNVQGRLTEKG-VDGQVMIKSGAPEKVILETADEVDADYIVMGASGSHGAdARGVLGGVTCKVINTGKRSVIVI--- +>tr|S7ITH0|S7ITH0_9FIRM Universal stress family protein OS=Megasphaera sp. NM10 GN=NM10_10615 PE=3 SV=1 +-SYQHILVPIDGSDHSKQALQHAIDIARITGGAITLLSVAnMADIInqfgqmentseLTMDEMtasaqanstglLKKFAAMIPASlSVQSIFELSAPEAAILAEQKSQSADLICMGRGGGQALKNFLLGSAQHLRHHPRTLPGPLGP-- +>tr|A0A0P7ZZC8|A0A0P7ZZC8_9CYAN Universal stress protein family protein OS=Phormidium sp. OSCR GN=HLUCCO16_10015 PE=3 SV=1 +-DPYRLLVGLDQTTLADQVFQQALTLAQDRQGELYLVHCLNLEFqgqlgtlldvgMglqsrinldelqqsqqvkqlkaaRRWLRQLCEQAAQRQV-PCDYRLDRRSPGPLLCYLAQDWSADLVVVGNGKKEVWQALILGSVSKYVIEHSPCPTLVIPG- +>tr|A0A1V4RF00|A0A1V4RF00_9BACT Uncharacterized protein OS=Candidatus Cloacimonas sp. 4484_143 GN=B1H06_00300 PE=3 SV=1 +---KSLVVAIEFPIKRRELVDIAKKMAVEFKAKLHIVHSesvdsyiqhivvednlqLTDEIMQQykenfkkQLNDLQDELSADKI-EAECILIEGPSVDGILKIAKEVKAEMIIIGSHEHGKFYHLIFGSTHNLLIKKSTIPILIIP-- +>tr|A0A1G0CQW6|A0A1G0CQW6_9PROT Uncharacterized protein OS=Gallionellales bacterium GWA2_60_18 GN=A2Z95_05360 PE=4 SV=1 +--QHEILASVGDTPLAQEIAKLAGGIAAACDLPLTIVGIAERQDArsraESLNTLYVALASALAKR-VQGRVCDGDPAAQTNAVAREISADLVIIGRQRYHLLP-FMHgkTSIMQKIIGANEVPTLVVP-- +>tr|A0A1H0SY73|A0A1H0SY73_9ACTN Universal stress protein family protein OS=Nakamurella panacisegetis GN=SAMN04515671_4338 PE=4 SV=1 +--ARTVAVGATSSPGGRAALKFASHEAIRMTASL--VAVIGADRHseqaRAILQNLEHvENECPGLP-IEIHWEKGDVAPALIRIS--QTSQIVVLGTHHSPDRWSIRLGPVTDLVLGHTACPVITVA-- +>tr|V4YM98|V4YM98_9ARCH Universal stress protein UspA related nucleotide-binding protein OS=uncultured archaeon A07HR60 GN=A07HR60_00401 PE=4 SV=1 +-MYDEILVPYDGSDEAMKGADDAIQLAAAVGASIRALYVinisgtpRSVYISqdDDElkedFRSYgrevATDLcDRASEEGVDCstVIRSGDVATEIVDYADAEEMDLIMMGSGYKGA-IGSLLGGKASKVVRNATVPVTTCRVT +>tr|D4YMY3|D4YMY3_9MICO Universal stress family protein OS=Brevibacterium mcbrellneri ATCC 49030 GN=HMPREF0183_1240 PE=3 SV=1 +---DSVVVGIDDSESAREAAHFAVAHFADArEIVLVAVIPdGTRpVLPApgdvttPytgslpavqpaipseedrkkceaMLDDLRTQlesThkdsETTSA-PIKTRVMAGDPAEQLATLGD--DAGLLVIGHHGADQKFAGRIGRTSRGLPGHSLCPVLIYR-- +>tr|A0A1C4ZUP3|A0A1C4ZUP3_9ACTN Nucleotide-binding universal stress protein, UspA family OS=Micromonospora purpureochromogenes GN=GA0074696_4920 PE=3 SV=1 +---APVVAGISVLPQAMEVVREATRAAAAHRRNLVLLHAFNWQAafeatsvaeprAeaEEMIARAAATAAEIEpAVSVSGEIVEGPPLDALIRRSES--AFLVAVGDGGMTTCGDCVPPDaPAVQLAARAGCPVLVVRR- +>tr|A0A0K1ECK5|A0A0K1ECK5_CHOCO Universal stress protein OS=Chondromyces crocatus GN=CMC5_027430 PE=3 SV=1 +-SYRKPALALELDQAACDVITLLLQTLPSPCPPVAVVHAYNA-PYQNLIYpslseeegagyrnQCrqqaiqgvAKLLaaavdqvDDPEatEVPWKTYIRHGSPRDVIPKVVETANIDLLVLGTRGYAGIAHAFLGTVAGEVLREVGCDVLVVPP- +>tr|A0A0D2WBF3|A0A0D2WBF3_9PROT Uncharacterized protein OS=Skermanella aerolata KACC 11604 GN=N826_05990 PE=3 SV=1 +-LYRRVLFAIDATNPSARAAYAARNLPFLEAADISVLHAFWAP-GKGKLRqagvnpariaqyveetalEAATDlvsfLHQEGRHdpIEKIVFTEGEPVSAIREAAARWRSQLAVIGIQRRTGLRRLLCPSSAKQILRQVTCDILAVPL- +>tr|A0A1I3P7Q1|A0A1I3P7Q1_9RHOB Nucleotide-binding universal stress protein, UspA family OS=Celeribacter halophilus GN=SAMN04488138_102224 PE=3 SV=1 +-PYKSVLCGIDLSPSCLAAGKAALEI--VPEAKFATFHAVHIP-YRGMLApeasekqlapfvkDANAEldkwWESSAIPkgLPKPTVTPSSVQDAFQGAMEESEADLFALGAHGRMPLSPTLLGGFTEYQIRNPRTDLLIVRD- +>tr|A0A1V5WZC7|A0A1V5WZC7_9DELT Universal stress protein family protein OS=Deltaproteobacteria bacterium ADurb.Bin207 GN=BWY17_04855 PE=3 SV=1 +--MKTIVAAIDFSDTTTIVIDTAVQLAHALHAEIVLFHATPPSGTwlmAGLDGltaaGMLHPVlwerqqqdilqqhldnliTqvQKQGLTVRSHTTSAVQRNAICQALESLHPDFIVIGSHRHGSLYELLGPGICSRIVRRAPCPVVVVHS- +>tr|K2J6P1|K2J6P1_9PROT Universal stress family protein 3 OS=Oceanibaculum indicum P24 GN=P24_00155 PE=3 SV=1 +--IGTILTATDLSPRAGAAVQRALALKREHACALVIAHIIDRPTSSLdverRSRTAFKTIDGQlQelppeeREDIAIKVTTGTPQWELGRLAHMHRSELVVLGRHEPRGGHDLLVGSTAEGLARDGNCSLLVVAD- +>tr|A0A1K2HSG8|A0A1K2HSG8_9RHIZ Nucleotide-binding universal stress protein, UspA family OS=Vasilyevaea enhydra GN=SAMN02983003_0158 PE=4 SV=1 +--LRHITLATDLTARSDRATERAIQLAAQFQAKLLVVHAVEAAVSaiwdggpsWRraldLAEMARRRLFGDlPlsqSVDIDVVVERGDPFEVVLRTCTDAGSDLLVTGVAREEIYGSSRAGRMVEQLASRAPAPLLVVKR- +>tr|A3TMN9|A3TMN9_9MICO Universal stress protein family protein OS=Janibacter sp. HTCC2649 GN=JNB_12573 PE=3 SV=1 +---GAIVVGVHNRPSDDNAISQGIRQARLSHRPLHLIHALSpgivpwtaeyie--TKNLALKECRDRAAEKASdLDISCTl-HVDEPAGVLVEASR--SAALVILGSSGHSRSVDVARTAITRKVISHAASPVLVTP-- +>tr|E6QN35|E6QN35_9ZZZZ Uncharacterized protein OS=mine drainage metagenome GN=CARN6_2142 PE=4 SV=1 +-PLRHILCAISLHSPAMLVAELATRIAADHGAELTLLHVMPTREEArldpgysa---TTLEARmrsllspPAQRQLR-IESISTTGDTAEEIVYQSNLRQSDLLVFGAHEASTLSTLVRQGVINRVLGQALCPVMTLAD- +>tr|A0A1E4K1H9|A0A1E4K1H9_9PROT Uncharacterized protein OS=Thiobacillus sp. SCN 63-374 GN=ABS92_16150 PE=3 SV=1 +--YRRPLAAVDFSPDSHAALAWAAHLSAD--GSAEALHVLPNEDERhlrgvglsaeav---RQRRVDmraiaknlmanlladM---PAQ-AAGHIEIGPAAKIILERAAERRADSLFWAGKVPAGWR---SGCWAA---------------- +>tr|A0A1Q3TUX5|A0A1Q3TUX5_9CHLR Uncharacterized protein OS=Chloroflexi bacterium 54-19 GN=BGO39_00640 PE=3 SV=1 +-GWPRLLLPLDMTDKAEAALNLSLELARRLRASLYLLKVNNPVPHShnlsgdpdalakldlYGKSEANFYleqieklAEEKGVE-VVKIVLVGNPETEIRSFADLFAPDALIMATHAAGTnlAGTSNPPSLTLEIMRRSHIPVFMVPL- +>tr|E3GX85|E3GX85_METFV UspA domain protein OS=Methanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S) GN=Mfer_1294 PE=4 SV=1 +--FKKIMIATDGSENAEKAAKVGIDLAKSVGGKVIAVYVMDERLMqpydvmedegKNALKRIQKIGRKKNVV-VDEILILGNPIEDLPKIANKVNADIVVLASQSKGKFERIILGSTTKSMLENCNVPLLITP-- +>tr|W6WZR5|W6WZR5_9BURK Nucleotide-binding universal stress protein, UspA family OS=Burkholderia sp. BT03 GN=PMI06_008774 PE=4 SV=1 +-VNQAILIYYDGSTEGKRALYRAGEMAFSPGAEIHVLavvdvmsaivsSAGLlSDiacsdivkKTWSVLDEALDHLSAKDIA-ACGHLGYGQVVECIARYANLVDADVIIIGYRLRRGLsT-WWRSNRAhIELLEHAVGRAIMAV-- +>tr|A0A0C2BZ21|A0A0C2BZ21_9BURK Universal stress protein OS=Noviherbaspirillum autotrophicum GN=TSA66_24450 PE=4 SV=1 +-MYRKILVAYNGTPESRGALQECIRLEPGPATEIHLLavvtpmpiviaAEFAaavpTIeeeeaeqrTMKQVLESGRLMLADAGLK-VIPHLEVGEPANIIAGMVQKLGIELVIVGHSRHKSFaMRWWRGAMDAVLVEKVHCAVMVAA-- +>tr|N0B4E8|N0B4E8_9RHIZ UspA domain-containing protein OS=Hyphomicrobium denitrificans 1NES1 GN=HYPDE_31043 PE=3 SV=1 +---HKILCAVDGTSHSDKAVQFAAELANRLGSKLTIASVNVMiggarsgamyikedREVQQVLDVAENAATGAGAKNVDTAFLRSREAaAGVVAYAEQEDYDIIVTGTGDKHGLSRLVLGSVAADIAGRAHCTVIVA--- +>tr|A0A136NCC1|A0A136NCC1_9BACT UspA domain-containing protein OS=Bacteroidetes bacterium OLB11 GN=UZ11_BCD004000521 PE=3 SV=1 +-FKKFYYAQQIFSAESKEAIRYAVKMGNQSQTVIHLIHTLEAPIvmdsnsamyyqkMIDTLNAsaendmNnLLAELREKYSGYQFTGvvkDNADSAESIVEFAKSIEAEAIIMSSHGRRGIKRLLMGSVTESVMRLSDIPVVIIR-- +>tr|A0A1S2I591|A0A1S2I591_9MICO Uncharacterized protein OS=Curtobacterium sp. MCBA15_013 GN=BIV01_18315 PE=4 SV=1 +--MTAYTVAIDDSVAGWKTVDWAVDAVEPAVDDVRLLTVSEFfgeaLTrSEHRLDAAEQRLRTvHPGLSVTHDVTGGPTADRLVADA--ALGDVLVIGAPQVHTLTAAITGRVAERIVAHATTPVVVVP-- +>tr|W8WT07|W8WT07_CASDE Universal stress protein, UspA family OS=Castellaniella defragrans 65Phen GN=BN940_00861 PE=3 SV=1 +---KDIVLATDGSAYSLQAARYIAQ-SGLLPAGGVVRILhvmaglparvshFVDaAAIQDWYNEESAKVLeptaeilRQAGVPHETESRVGFAPQEITRYADEVDAHMIVMGAHGRGVLLDAVIGSVAGRVLALTQRPVLLIQH- +>tr|A0A0B7A582|A0A0B7A582_9EUPU Uncharacterized protein (Fragment) OS=Arion vulgaris GN=ORF94165 PE=4 SV=1 +----PRIERYGGVACRPYVTCKGFSKHVYKLGDEVVLVYVPEGHGllsaskwenavytlsrdvMmAASEEEEQKIKTDL-erfavklhelglEGKVRNVMASKPEEGILRACEEENAEMVVVGSRGKGTLRRTFLGSVSDYLVRHATCPVVVCKR- +>tr|A0A1Y2CNP5|A0A1Y2CNP5_9FUNG Adenine nucleotide alpha hydrolases-like protein OS=Rhizoclosmatium globosum GN=BCR33DRAFT_657677 PE=4 SV=1 +--TRVICVALDESKYAEAAFNWCLKHLCRNSAesnglidEIVLLHVRQLPLKlstslgddmipdatvysneeyVnWANQQSLVGSQELLKkygnrlmdlnkgVVIRCVSLTGDPRAELVDAAKNLKAEMMVVGTRGMGLIRKAMIGSVSDHLLHHLECPVIVVRA- +>tr|A0A0L0FI71|A0A0L0FI71_9EUKA Uncharacterized protein OS=Sphaeroforma arctica JP610 GN=SARC_11021 PE=4 SV=1 +-APRTIVVAVNNSEGGVYAVEWAFKDFVRPTDNVILVNvvdt-ythYiPNFgtTVTfdMATNHVQKEvvenaqtllaylakqMsMrPGQI----eTKVIAGDARDVMVELTEEQDIDVVILGTSNKTLLRRKLVGSVGSYLVEHCKCSVIIAK-- +>tr|A0A0F8XZU9|A0A0F8XZU9_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_3154580 PE=4 SV=1 +-------VPYDDSKYSERAFSLALDLANHYGASITTITIVYENpaTDLDirHQTSFDkdkikkinekfkllqEIATKFGITLKNDIAKRREILDPILTYITENKMDLVVMGSRSRSGPNQFVLGSIALGVCKSAKCPVMLV--- +>tr|A0A1X1TZ47|A0A1X1TZ47_9MYCO Uncharacterized protein OS=Mycobacterium engbaekii GN=AWC02_06095 PE=4 SV=1 +---GLVLAVVDGSSAGDGVLELGAAEARLRGLPLRVFALPQHRPAapgesdVPSDPPLPTAVDRWlsRCrqehpdLDVDSVGYHEGLLNCferLQRSGS--AIQLAVVAPRRPGPLD-VLLAPAGRAVVESAGSAVLVCDR- +>tr|A0A1W2DDH8|A0A1W2DDH8_9RHIZ Nucleotide-binding universal stress protein, UspA family OS=Fulvimarina manganoxydans GN=SAMN06297251_11449 PE=3 SV=1 +---TTLIIGIDGSKAGERALAHGKRLSRLIGdCTLLLVYVIEWSPYKfqsaeenamrhkrreeeieiakmRVIEPLLSALKSEGLD-ADCRVRHGDAAEILNAVALEHRAEQIVVARGSESGFASRVFGTVAIKLVSSASVPVTVV--- +>tr|A0A1Q4E5I8|A0A1Q4E5I8_9SPHN Uncharacterized protein OS=Sphingomonas sp. 67-41 GN=BGP17_16030 PE=3 SV=1 +-MFHHIVHANDGSENSLTALRTAIELAAVADTGLDVLFvediaprtGMIADVtAheteeRRHI-GRHKALAERiaarSGVTLKTHVFTGHPVGHIVAFTREAKADLLVIGATEHADLWEHLFGRRSDRMTHKVDCSVLIVR-- +>tr|A0A0E9M5T9|A0A0E9M5T9_9PROT Universal stress proteinc/MT2061 OS=Ferriphaselus amnicola GN=OYT1_00927 PE=3 SV=1 +--FERILLATEHTEFDVGAERVAFALSKHCGLPLDGVFPMRSNPEYEIEapqlvvkaeREAAAKIAqicaAAESqgVELNVSARRGeMRYREVVEEATRLHSDIIVVRRRGKRGfLAQLMIGEMVSKIVGHAPCSVLTVP-- +>tr|A0A075WVZ0|A0A075WVZ0_9BACT Uncharacterized protein OS=Thermodesulfobacterium commune DSM 2178 GN=HL41_08290 PE=3 SV=1 +--MEKILIATDGSQAAEKAAKLGVKWAKIFNSKLYGLSVAEVIPLGPELmevypklieileKKAYEAVDfikkEASQegLTCETFVLSSsDPLEIILDKVQRLGISMLMMGRKH-------TLGRVSRSLIGKSPSPVTVVP-- +>tr|Q7UER0|Q7UER0_RHOBA Uncharacterized protein OS=Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1) GN=uspA PE=3 SV=1 +----RTLIGIDSSAPARDALQALSKSTLAEACEVSLATIVPEPPLYTIDDtsmpwipqEVFDSRLEIEntqlkqlQqefgeRfsSCEFSVSQGHPGRGLIEMSERFDADWIVIGSVGHSAFSRILLGSTSDYVANRSTRTCLVHR-- +>tr|A0A0Q9U9Y2|A0A0Q9U9Y2_9MICO Uncharacterized protein OS=Terrabacter sp. Soil811 GN=ASH01_11225 PE=3 SV=1 +---GEVVCAIAGGDGEEHAARVERIVSAASRIAVACSASLRLV-----tvtrggVSDAaRQRIPYAvaSLtsrhpaLVVTVEILTGDPVTVLAEATR--HSGLLVVGAPLRGGATAVLSGQASYRLIRDATCPVMLVP-- +>tr|W5TKI3|W5TKI3_9NOCA Universal stress protein OS=Nocardia nova SH22a GN=NONO_c49000 PE=3 SV=1 +---RPVAVGVNDE---NAPIDLAFDEASLRGVAVMAVRACDEMAGAF-awtgepgrIRTDeTRALTEHlaPWtrrrpeVGLTTTVVFDNPAHALLEQSD--DAQLIVVGRHGWNGLTAMAGRSTRTTLLHRSLCPTLIVPE- +>tr|A0A1E3SV79|A0A1E3SV79_9MYCO Uncharacterized protein OS=Mycobacterium sherrisii GN=BHQ21_12540 PE=3 SV=1 +---LPVLVPVESCPSCEVAVDVGFQEASRRGVDLVTVYSPNRAIQRERfpvaggVLAPiGELADEYlqPHrgrypdVTVRSVQSYACSDVPLREVSR--ATQLIVICDRAAQGFSGLRLGPLTCTVLGSVRAPVLVARR- +>tr|R4LEX6|R4LEX6_9ACTN Uncharacterized protein OS=Actinoplanes sp. N902-109 GN=L083_3413 PE=3 SV=1 +--AGPVVAGVDGSASGPATLDVALQEASLRKTSLVALHAWADADMSPLdpphggdgdhrrGLARGQRALAealAGAgerypdVAVRREVLHGDAGMLLTAWSQ--AAQLLVIGDRHHHGPGSFALGPVGRRLIFHAGCPTTVVNA- +>tr|A0A0K2RCI1|A0A0K2RCI1_9MICC Universal stress protein Rv2623/MT2698 OS=Arthrobacter sp. Hiyo8 GN=AHiyo8_08540 PE=4 SV=1 +--RRGIVVGADGSEESTQAVSFAAEEADKDSQELTVVHAVLAP-PliQ--rvmpasdvaetVLEEERIVLAetvAGLaenypdMVVHQALVsNNEPGKHSWTPPP--MPHCWCWEAvegaaSNASSWDRLP-------TPYSGPCPAQ----- +>tr|A0A0Q9Q7R8|A0A0Q9Q7R8_9ACTN Uncharacterized protein OS=Nocardioides sp. Soil777 GN=ASG88_15200 PE=4 SV=1 +--RRV-VVGLRWPPhEDEALLEEAFAAAERWHCDLEVVHAGRAQGSrrDPPtprghdpgWVPGLTALVEehlVVPrrrhprVHVRVDVVr-SSPAEALMDSVG--PGTVLLVSRT-SDASSAPALGPTSRGVLHLARCAVELVPA- +>tr|A0A0E9N1Q2|A0A0E9N1Q2_9BACT Usp family protein OS=Flavihumibacter petaseus NBRC 106054 GN=FPE01S_02_08090 PE=3 SV=1 +---YNFLVPIDFSHTAKNAAKFAIDMARdLNDVQVTLYHLLDPIaagsdgTPldidL--ddRIKVaEVALSnlatelgA--PANTRTIAADGvFLIDDLAEFVQQEGIDMVFIGLTGASGIEHLLMGSNAIRMANEAVAPVMIIP-- +>tr|A0A1M3IF86|A0A1M3IF86_9BACT Uncharacterized protein OS=Bacteroidetes bacterium 43-93 GN=BGO70_03900 PE=4 SV=1 +---SLIITATDFSTIANDAVHYACRLAHAYNATVTVVHAYNIPvtfnenPMpvm-PIeesRAIAQKSLDemvAslsktYPGLQINSHLTFGDITEGMIDFAKNNKPWMAVVGNSLS-EDDTYWFGGNLLQLMRDTPFPVLAIP-- +>tr|A0A0Q5TTF3|A0A0Q5TTF3_9BACT Universal stress protein UspA OS=Dyadobacter sp. Leaf189 GN=ASG33_06035 PE=3 SV=1 +---NRLLIPIDFSENAEHALNAAKIIAEKGATELLILHAYQPYIadvnltpggvlpgvggadflaMTTdleddyrnRLDQYADNLVAQGYN-ARALWMLGSVQSVVEEAIEEHQPAMVIVGRTGTGGFLDKLIGSSATHIALQSKCPVLVIPP- +>tr|D2B9A2|D2B9A2_STRRD Uncharacterized protein OS=Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) GN=Sros_9016 PE=3 SV=1 +---GRVVVGVEGANVERSGLGTAFEEAKLRHATLLAIClcpegled--------tRPLAARFHSTISvweekYPQVNVETMIETRPHTAVMHSAAE--HADLLVVNDREQDDPVELPLGLVSQSLLRGASCTVTVIPS- +>tr|A1T5M8|A1T5M8_MYCVP UspA domain protein OS=Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) GN=Mvan_1649 PE=3 SV=1 +-ERPRVLAAIAPDTGFrdtatlnRTVVEYALSMAAIEEGVPVLLQAFKP-LVLHV---ThdldvetqdvveqrrtevIadlhRMVRDLGEDprEVEVNANLGSIDHVLPDFIVSRGIDLVVIGVSGRRGLARWIFGNSAERLLPRLPCSVLAVKL- +>tr|A0A0Q7EZP1|A0A0Q7EZP1_9CAUL Uncharacterized protein OS=Phenylobacterium sp. Root1290 GN=ASC79_18585 PE=3 SV=1 +-AFRQAVFATDMSEASAASHAVAVSMF--PEPVYAYLYAFDA-PL--AGL-vEdrgeftadaaraaEkeleAFAMALPVHrdagTPALVTKYGAPARTLCEHVALVGADLVVMTASSRGLFAELLLGSVVKDALECLTSDVLLVPE- +>tr|A0A024IYT7|A0A024IYT7_RHIRD UspA domain protein OS=Rhizobium radiobacter GN=BN949_03726 PE=3 SV=1 +-TRDRIVVAIDLSPAASGVLATAVRFF--RPESLVLFHAIEP-TYKNWVD-dKeaysrqiskeaVkqvrSLSDDFTQHggarEIQIVTLEGDPVQQLAAYVDDNDIDLVIAGTEGRHQIMNLFVDSVAGHNPHEVQCDIMIVPR- +>tr|A0A1Q8TAY8|A0A1Q8TAY8_9GAMM Universal stress protein OS=Chromohalobacter japonicus GN=BTW10_12815 PE=4 SV=1 +-AWQDVLVPVDFSLASRHTLRDVLTHF--PQARLTLLHAWHL-PGddemGSDSGYArwrerelaarrirlEaeidKLMEEVGD-vpELELVLEQGDPGEVLMDYLRRQPPDLLALGHQDLALFGRHQPAPLIERLLAEAHVDMMVCRA- +>tr|A0A240UPD6|A0A240UPD6_9GAMM Universal stress protein OS=Kushneria marisflavi GN=B9H00_07590 PE=4 SV=1 +-DWQDILVPVDFSLASRHTLKEVLMRF--PNVRLTLLHAWDM-PVamelCEGTNYQhwrdlerqrlrqqlEleteRLMADLHA-kpDLELVLQQGDPSQVLLDRLRQQPPDLLALGSHIRVGIGRAT-DSLLERLLTETRGDLMLCRT- +>tr|Q020X8|Q020X8_SOLUE UspA domain protein OS=Solibacter usitatus (strain Ellin6076) GN=Acid_3539 PE=3 SV=1 +-GFHQVLCAIDLALHSREVLAWADWFAREYAAALTIVHAIPSAATrrggfyFDpdFgVELTRH---A--SERIEllkedlnikaaVDIEGGETPLVVANAAESLKASVLIIGR-GSTPRAHGHLPTNAYAIVRESPCPVFTI--- +>tr|A0A1Y1RDZ7|A0A1Y1RDZ7_9BACT Uncharacterized protein OS=Candidatus Cloacimonetes bacterium 4572_55 GN=B6244_13325 PE=3 SV=1 +-DINHVLFPTTGSALCYHVFPYALDVAYRFNAKLTLLHTIFDSGPrFTdrIfPTHHFNl-DSL--RDDQVeqVTVYAETAADGILHYSRVNSVDLIIMPSKLARGH---HLGRTTDAVLVGSECPVLTVNP- +>tr|A0A1Y3XWX6|A0A1Y3XWX6_9ACTN Uncharacterized protein OS=[Collinsella] massiliensis GN=B5G02_04375 PE=3 SV=1 +-YFRNILVPYDESDHALSALHTALAMVGDePDAKVHVVTIiparALPGVPFTgdgfdvsptvvnpesydqLMDVLVSrtrtDLQQ-VVkeslDGarckvSVDAVIDASPVEGIANYVENNNIDLVVMGRRGVGALRGM-LGSVSYGVLRSVDVPILTV--- +>tr|A0A1F8RZF7|A0A1F8RZF7_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_70_13 GN=A2V84_05320 PE=4 SV=1 +MAGMRFLFATDGSTGAGQALRLLTSSFEPSGvESVEVISVVPLVLRgPDAGpsdaahavieqgqRDAaeqhvhgaAELLRGAGFEAV-ETVRVGHPAETIVTHGIAHRADLIVLGTRGLSGLRRRVVGSVSGKVARYAPSSVLVART- +>tr|M0GWR2|M0GWR2_HALL2 UspA domain-containing protein OS=Haloferax lucentense (strain DSM 14919 / JCM 9276 / NCIMB 13854 / Aa 2.2) GN=C456_03136 PE=4 +-PYENILIPTDGSATATHAAEHVVDFAASLDATVHVLSvvddRVLgldsratasgnesEQAATDAVDTVVSEAEARGVTNTVRHVEYGTPVEKIRDCIEANDIQPSGWGRWGGVARIVSCLAVSLKRLCARHQCPS------ +>tr|J0S2J1|J0S2J1_9EURY UspA domain-containing protein OS=Methanofollis liminatans DSM 4140 GN=Metli_2190 PE=4 SV=1 +--MDSMLVPLEIHGAAAAMAPAVEEIARLGVERVELLYVinIRETagdpgi--HahdrEVMDGWTKRLETCGVPDVGAEVVAGIPWIEILERAEAAPPSLIVMGSHGRSLIPRVVLGSQTENVLAHATVPLLILR-- +>tr|A0A139CNB7|A0A139CNB7_9EURY UspA domain protein OS=Methanohalophilus sp. T328-1 GN=AWU58_1426 PE=4 SV=1 +--IQTILIPTDFTIESEKLLSCIAELKNTGLKKAILLHVvdIFKSqglapMFEenakKKIAEYKQLLEEMGID-TVTHVVEGDVNKTIIKVADEENVDCIVMGATTSGVIKGKLTGRTTNYISRRSDKILLIEK-- +>tr|M1E8X6|M1E8X6_9FIRM UspA domain-containing protein OS=Thermodesulfobium narugense DSM 14796 GN=Thena_1837 PE=3 SV=1 +--IERVVVALDFSEQSSKLFNAVNDFKRFGIREIHLVHVvsPDALevnkei--VkiasDHFSLYIKNYLSEGVN-VFLEILIGNVVEQIRDYCEEINANLFFASEHGEGFFKDIFVGSNLFNFIRTIKRPIYVER-- +>tr|D0LIT9|D0LIT9_HALO1 UspA domain protein OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_0327 PE=3 SV=1 +-GYQRILVGMDFSSTAQEALRYAVALAAPGAVvDLLHCwrlplASVPYFPAGDVgasIEGPLrTYTEElgqklasehsTPTCAVNYHSVEAAPTQGISEWLEARPYDLTVVGSHGNRGMRRFLLGSVAEATVRHANTSVLVVHA- +>tr|W0JM47|W0JM47_DESAE Uncharacterized protein OS=Desulfurella acetivorans A63 GN=DESACE_06730 PE=3 SV=1 +--LSKLLVAVDSSPYSTNAIKFALDFGKKFDCIVDAlhvvdtmqlegpfiydlSGVLGFEPfinfsaelkktleekGRSILQAFSEMAQNENVKF-NSFIEVGIIPITIVETSY--EYDMVFIGKKGInASFERGILGSNIESTIRKIKKPIFVA--- +>tr|A0A1G3Z2V4|A0A1G3Z2V4_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium GWC2_42_7 GN=A2007_05095 PE=3 SV=1 +--MEKLLVCTDGSHDSEVCYAYAAWLAKRTHALIDVlyvsdlrqfemsmvtdfSGSLGVQPfqgvfsqlqdiekekTKLIGSRVHKVFKKYGIEE-DRVKfhqRTGFLTDCFeeFSEDTE-GFDVICLGKRGEnARIATEHLGSTMERVIRSATKPCLVT--- +>tr|D5AWB8|D5AWB8_RICPP Universal stress protein UspA-like nucleotide-binding protein OS=Rickettsia prowazekii (strain Rp22) GN=uspA PE=3 SV=1 +--FKNILIPIDLNDKksIKSIFPKALMLAINFQAKLHFMYvipefgtkmfeDYLPKNWRIeKKEKYQTQIKDIIKQYipdtieTDNYIGSGAVYDEIIKRSNEIKADLIIISAV-RLQLKDYMLGPNASKIVRHSDISVLVLR-- +>tr|A0A1A8T9R5|A0A1A8T9R5_9GAMM Universal stress protein F OS=Marinomonas spartinae GN=uspF PE=4 SV=1 +--YKCILVPVDWGHEhsWQSLLSASIDLARRHHAQLMVAFidpnsdtptlaNFLPKGTSHl----LEERPNPFIAEHisknirVPFQAEQGQIYSEILYIASVLNIGLIFMALH-TPNLANQLIGANAKKVVRHPQYSGMVCK-- +>tr|A0A1V3ISZ7|A0A1V3ISZ7_9PAST Universal stress protein UspA OS=Rodentibacter rarus GN=BKK50_00290 PE=4 SV=1 +--YNNLLLVIDLNNPatAKTVVDNALQLTANNpEAVYRVVTivepvddsfisAFLPKNFDKsLINEVKNALHRFTEKHfpitakVQHIVAHGTIYEEIIRISEEKAVDLIIMLASSKSsvK-----FSNNTRRVVKYGTKPMLILK-- +>tr|A0A0J8YH01|A0A0J8YH01_9BACT Uncharacterized protein OS=bacteria symbiont BFo2 of Frankliniella occidentalis GN=AI29_05400 PE=3 SV=1 +--MNTVIMAIDHQNNlSATIGQLTLQEALLRNASVVVLcclpTEGGVegEVmniecaidqvvqQYgqpkdplncaeTAVRAALVLFQQSGI-LAWGLLCRGEPAAVIVEQANKLSASMIIMGRRHLSLFNRLFKGSVSAEVLETASCPVLID--- +>tr|A0A0W0WWG1|A0A0W0WWG1_9GAMM Universal stress protein OS=Legionella nautarum GN=uspA_2 PE=3 SV=1 +--YTTILHPTDLRENHFDMSKQAVQIASQFNAKLHLLHVIEPPATYQLaqglgftelavpvKEDAETVmkylGEALDIPPEQQHVQVGPIKQQIMAMVNNLGCNLVIIGSHTPRAV-PAFLGSTAYAVIHQAPCDVLTIRAQ +>tr|A1RV78|A1RV78_PYRIL UspA domain protein OS=Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3) GN=Pisl_1709 PE=4 SV=1 +---RRILVPISPMNPvrLRELLNVAADFGERYGADIVFLYVSISENDptaEQLKTTVEEFMN-K--KGikHFfkvrkM-GEGETVASEIVKELSENSYDMVILLSRGYYGASALLYNSTSVAVALAANTSVLIL--- +>tr|A0A101XFW2|A0A101XFW2_9CREN Uncharacterized protein OS=Thermocladium sp. ECH_B GN=AT710_08665 PE=4 SV=1 +---RHVAAVLDGSRASLRALPVLKDFAQRYGSRITVIYQGSDDEFl---SLVKESMS-GAGIT-YTv------EKPSDLLEFIRNKAPDLLVLPLEGRTGAEALESAGPILSALAYTESSILVL--- +>tr|A0A1Y5DFB3|A0A1Y5DFB3_9GAMM Universal stress protein OS=Marinomonas sp. 42_23_T18 GN=A9Q77_08705 PE=3 SV=1 +--VKTILFACDLEDKTQESLALVMSLAVTQNAKIIFMHAiepmnhqaqsminnYLPIKELQALRqDALNsvkdametQITIFyenhaaetkLTEKPEYLIVQDDASSAIKHAIKDYQVDMVVMNSRTHSKLGQMIIGSTANKVIHQSKVPVLVIP-- +>tr|I3ZGU7|I3ZGU7_TERRK Universal stress protein UspA-like protein OS=Terriglobus roseus (strain DSM 18391 / NRRL B-41598 / KBS 63) GN=Terro_2200 PE=3 +-DAGPIVYATDFHEGVEESMAYAAFLSHQQQVPLHAIHVLPKSSI-DtknhiVA-KIMQtalaDLqItsGKEALQPSSHAVFAkDVSKAIVEYAREVHASAIVLGVNRRSSFASHLPLRRTSRVVILAPCPVFTLAH- +>tr|A0A0P1J4X4|A0A0P1J4X4_9GAMM Universal stress protein OS=Alcanivorax dieselolei GN=BN2364_3825 PE=3 SV=1 +-ALEHVLMATDLSKYASGAENLLRELSTQAKRIDLLtVLTPDGLnntPAlpVMALAALNHIRDYLPDEAgeVSVLTERGAPAETILRIAAERDCSLILIGKHGQGWLESKLVGTTATEVCEAAQRPVLVAP-- +>tr|C5A3N9|C5A3N9_THEGJ Universal stress protein (UspA) OS=Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) GN=uspA-1 PE=4 SV=1 +-IFSRPLVALDFSKCSIRIVKTVKKFEELIESGILLhSVDYGGIdelEHniEIARKNLEKTAKGIKAE-FELEVMVGTASQAIIGTALAKKATIIVIGKKGRSFLKDLILGSTAERVMRDSKIPVLLVP-- +>tr|H0J6E2|H0J6E2_9GAMM UspA domain-containing protein OS=Halomonas sp. GFAJ-1 GN=MOY_16078 PE=3 SV=1 +-SYTTVVLATDMSAAASKAERLFHSLALHFQHRVAIiAESLLETdgyGFEEAQLHLTALAARIPKL-DT-VIVAGEFKQAIINEANAWHADLIIVGQQGHSRLRERLLGSTAKALLEGAACPVILVP-- +>tr|A0A0C9MH31|A0A0C9MH31_9FUNG Uncharacterized protein OS=Mucor ambiguus GN=MAM1_0021d01840 PE=4 SV=1 +---RRVLIGYDHTEVSNAAMEWIVnKRAVFADDEITLAIIVNDdaiaveGtfglesavagPAGWladDYReriskverESTAAlnavvkwFASKGIT-VVPRILSGEPGETLKDFAEANKVDLVIVGSRGLGFFKRyVQRAEILPeQPTEHIylKIGNLLAL-- +>tr|A0A0A8WNC1|A0A0A8WNC1_9DELT Universal stress protein OS=Geobacter sp. OR-1 GN=OR1_00553 PE=3 SV=1 +--FDNILFPTDFSEGAERVIPYLCKITSEMKSPVTIFHVIAETEIDpakkeqredterFLLDAKRQRILKGCgsgnasepasgevtenscesIQGISVELAWGNPGQQICTKAIEGIFSVVIMGSGGKGVTKEFFLGSIAKEVARHADVPVIFIP-- +>tr|A0A126V0V3|A0A126V0V3_9RHOB Uncharacterized protein OS=Halocynthiibacter arcticus GN=RC74_09655 PE=3 SV=1 +-KGCDVMIFLEGAHVETSAPFHAQKVANAFSGKVVLVHIMADPhDGkgpid--pvdwdiKKQKTMKDLAErarpfagEDGPECEVKLLEGQCIGQVSDFVDHRQGGIAA---ALRSTDGLgWQSSDTACGVLLSQSAAILMIPA- +>tr|L8M5Y5|L8M5Y5_9CYAN Universal stress protein UspA-like protein OS=Xenococcus sp. PCC 7305 GN=Xen7305DRAFT_00049870 PE=3 SV=1 +------MIAVEKPPLAFKVADTGFALAKALNAQVLLMHINPPALLYSpdsgtspdqikyqMNREAENflqKLvKLYGDnLEVSSFILEGNTEHEIIKAINDIKPDILILGTHGKKAWQELLLGSVSEDIIRHSTCPVMLIRE- +>tr|A0A061N3J7|A0A061N3J7_9BACL Universal stress protein family OS=Geomicrobium sp. JCM 19055 GN=JCM19055_1562 PE=4 SV=1 +-AYQNILVCLDSENEpTFHAYNEAISFAKNESATLYLCSIINTKAYGAMSRYDknlvpqvkqmatdylshlHQKATTAGVNA-KLIVDTGLPVQKIVKsVVPRYNIDLIIHGATGGNKIEKALEGSISKGLIKKKPSRLFSCKA- +>tr|A0A1V5SXW2|A0A1V5SXW2_9EURY Universal stress protein OS=Euryarchaeota archaeon ADurb.Bin294 GN=BWY45_00816 PE=4 SV=1 +--FTKVLIPYDFSDDAEYIIRCLKNIPRIREVILVHVtrSLYLVSSPERenpEADYARLRlekvrdlIEMPRSKvrIIVEEITGGEISDAVIRVAEREQVSLILMGRRGRGVIETILLGSTAWDILRFCPSSLLLIH-- +>tr|A0A0Q8QMS8|A0A0Q8QMS8_9BURK Uncharacterized protein OS=Noviherbaspirillum sp. Root189 GN=ASE07_22755 PE=3 SV=1 +--IETILVATDYSEQARRAETRAAMLSVELKVSTLEILavqetrmglntpatasQSTELDTTavdNVLVENrlpVSLIQSVEALQCIRSLAVGKPASAIARRADELNADLTIVAARSKTFVPDFFTRDDNDELVRLCNRPVLLVHT- +>tr|A0A1M5LAU9|A0A1M5LAU9_9BURK Nucleotide-binding universal stress protein, UspA family OS=Massilia sp. CF038 GN=SAMN05428948_1307 PE=3 SV=1 +--SKKMLLVTSEACLSQRAALRAALLSGDLQLDGFDMLnikrsalglcagNTEYSQIevrGhavSAWIDGkrtpvd--VLDDANVLAPIWHTARSTAAELVAETARAQRAELTVLAPQRRHSLLALLAPSHSRAILRQSQNSVLFVHC- +>tr|A0A0K8PHZ8|A0A0K8PHZ8_STRAJ Putative UspA domain-containing protein OS=Streptomyces azureus GN=SAZU_2257 PE=3 SV=1 +---NRVVVGVDTDDASLQALDVAFLEAGLRGARLDMVHCASDTATSPTGAVttvpvdptwvrSGQREffdtELGRRrdrhpgVEVNLRIEHASPGQLLVEAST--GACNTTASVLSRhtgydADITRAILQACATA---CEACADE-CSA- +>tr|A0A0Q5ADI8|A0A0Q5ADI8_9MICO Uncharacterized protein OS=Rathayibacter sp. Leaf294 GN=ASF42_13820 PE=4 SV=1 +---AQVVVGVNGSSASLAALEFAAAEADRRRETLLVVRSWHLPAVEEdsadrpagrvaHELEDHRLRvLdaVAPVreqfprLRVELRFAHGDTVQGLLASAS--DAGLLVLGTDASA--LRRAGERIGHALVLTTHTALAVIPP- +>tr|A0A101FTJ8|A0A101FTJ8_9EURY Universal stress protein OS=Methanosaeta harundinacea GN=XD72_1476 PE=4 SV=1 +--FSKVLCTTDFSEASKSAISVIRDLK-DAVGEVILEYVVSRGETQeeieGYVAEAKEKletikedLVGAG-LKVRTHVDVGNPRDQITRAVLWCLRHHSFENHTG--------ISIYMFDLNPSHQGANLNY--- +>tr|A0A125QJR7|A0A125QJR7_9SPHN Uncharacterized protein OS=Erythrobacter sp. YT30 GN=AUC45_10555 PE=3 SV=1 +SPYRHLIAGTDFSANSRYAILEAAKRFP--NAQLHVAHGW-RVPFQGFQRdtyvreeieeDARSAMEAfmadlakanPALANATSNVAKGNAYEVMAREFdaycDIGGEGLVVVGSHGESGFRQAALGSQTSDMLRYLQNDVMVVNT- +>tr|L8JSU8|L8JSU8_9BACT Universal stress protein family OS=Fulvivirga imtechensis AK7 GN=C900_02169 PE=3 SV=1 +-----------------------MEMVARAKAEVVVLHAayvpvlYDPGYAggtplaydisflNRIEEDTKRGYEKMknesGVRGVSVSLDivHDNLISAIQHHVDRKQTDLIIMGTSGASGIREVFIGSNTEKIVRFAQAPVLAVH-- +>tr|A3CVG2|A3CVG2_METMJ GCN5-related N-acetyltransferase OS=Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) GN=Memar_1433 PE=4 SV=1 +----KVLIPTDFSAASVTMAERVGEVPGVREVVLVHAQRSAALssADEDALRRMRELVQRQGFPVEVVvAEDDGTDLpARILRTALATGANLVAMGVRDQGLLRNLFSGNVAATVLRDARVHVLIVPQ- +>tr|A0A0W0SKE5|A0A0W0SKE5_9GAMM Universal stress family protein OS=Legionella cincinnatiensis GN=Lcin_2100 PE=3 SV=1 +-AYNRIVIATDLTEASKETVQFTFNRFPKAIFQLLHIiNIHnqqffnptdiseefvdpKQPKTKSIFEKLDDFLNQCQVDksKFEKKIMGGYYADCIIRQTQKWNADLLAFGTQSKSRLHYLLMGSVAKRILHLSTVDMLAIP-- +>tr|A0A1I7G2U8|A0A1I7G2U8_9PROT Nucleotide-binding universal stress protein, UspA family OS=Nitrosospira multiformis GN=SAMN05216417_10396 PE=4 SV=1 +-KYKHVLVPVDFSKNSLNALEMALKAVMDASIHVLHAvEMPlgqkmkqagfdaeqvehfRSQILIHAREGMEKIVSDYAHGdrRVASLIEYGHAPDMIREKAQALDIDLIVIGKRGQTELDEALFGSVTKHVLYETPCDVLVVN-- +>tr|A4BHU3|A4BHU3_9GAMM Uncharacterized protein OS=Reinekea blandensis MED297 GN=MED297_09416 PE=4 SV=1 +--YQHILAPIDVSVptIGEQILEKALFHLRYGNADITLLAVAPVKAD--enAIDEIRSQlmafAEHHIaanEGRIHLKVSQGLPSDQVLKTATDIQAGAIFIGSHR-GGgsqLGRPTLGSTAAKICSQAECDVVVV--- +>tr|A0A1W6PGG7|A0A1W6PGG7_RHIET Universal stress UspA-like protein OS=Rhizobium etli GN=TAL182_PA00100 PE=4 SV=1 +--YRTIVCGIGMDSrqTAKHLLRRAAALVD-EGGTIVVMHVIENIPRHHltdipeefeaaAIIDAERKlaslCKGAGhsgdd------RGSH---RRCRLAARV--GRKGESHPGVI-PDITDYVFPSIVEKVVRHAGCSVLID--- +>tr|A0A0F2ITJ7|A0A0F2ITJ7_9BACT Universal stress protein UspA OS=Candidatus Magnetoovum chiemensis GN=MCHI_004097 PE=3 SV=1 +NLFDKILICIDNGRLSDVMSDMTTKIAAGFGSAVVGLHAYNAVmhedafrimeptlpAQYqkeeilQKQRNSHTdlisvgmekislsylkpieqIFNGAGIE-YRSKVKEGKNFKALNQMIAEEDGDLVVIGSSSFNGNgngnGKGYLGSVCLRVLRDSGrRDVLVVK-- +>tr|A0A143PTH8|A0A143PTH8_9BACT Universal stress protein family protein OS=Acidobacteria bacterium DSM 100886 GN=LuPra_04718 PE=3 SV=1 +-AMEEVLAPIEFHDHAFDDASLADRVARASHARLRLlhvvaggeE----SRwtvlqPtMaslledeLSGLRasvtGAAHQALERLAESLGGTPgptlevve--GPVAERIAQVANRAEVDLVVLALRGVPGLLGTRVGTVAYRVLCASPVPVLAVPHE +>tr|M7DGU3|M7DGU3_9ALTE UspA domain-containing protein OS=Marinobacter santoriniensis NKSG1 GN=MSNKSG1_03245 PE=3 SV=1 +--FNKVLVGVDFSPA-ESAlLSCLPELKRWGTDTLVMahmvPVGYTSISGYgheadylKDLEKTAEPLRQAGLTV-ETLVRdSTHPAKAFAALAGEMDANMILVGSRSHNFLHKLFLGSFATEVLQHSRVPVLIERI- +>tr|A1WZS8|A1WZS8_HALHL UspA domain protein OS=Halorhodospira halophila (strain DSM 244 / SL1) GN=Hhal_2427 PE=3 SV=1 +--FDHTVVAVHFESP-YQPlLDAVSELHKFGAKQFTLvdvlRIDDPDDLSEghraearRRLAQKQSDLQAAGYQV-DIQQPIGFPAPELAKIGRGYGAQLILLGSRGEGLLREFYHGSTVLELARQTALPVLMERI- +>tr|S0G1B8|S0G1B8_9DELT UspA domain-containing protein OS=Desulfotignum phosphitoxidans DSM 13687 GN=Dpo_1c02770 PE=4 SV=1 +-KVQNILFASDLSVDMKPVFEQAVTMATYTGANLIVLHVmeeaspsaqrqvkmAFGENLYKEIRAKHksgaqDlligknvdalrirqaiagFFEDHEKvSADAVSPikkilvaESHSIADEIVSSAVDEDCAFIVMGCRQQGLVAQAMGDKLVRKVLKRSSVPVFVVPR- +>tr|A0A099SES6|A0A099SES6_9FIRM Uncharacterized protein OS=Desulfosporosinus sp. HMP52 GN=DP73_08025 PE=3 SV=1 +--YHKIVVPVDSAGHSKNALIHAIKLAQQTSSKPMVIYinpiipLYLnfglvPVRKYVPLENsdAldilKDIIADMGipPDAIDRRAATGDPTTLIIKIAAEERADLIVMDNKLFGRLAGF--RNISNSVIKHATCPVLVVK-- +>tr|A0A0A2RPZ3|A0A0A2RPZ3_MORMO Universal stress protein G OS=Morganella morganii GN=LR61_04095 PE=3 SV=1 +--HKVILVPIDLNHNYLtdKVISEINEFSVNKNTHFYFLTVISPAEKYNeygvgypmitEdTKFEDETSKTIekelkevvSkfgipDNQVSLLVKIGSAADIIIDVSQQIKADLIIIGSRNP-SFKTHILGSTASSLAHYAKTSVFIV--- +>tr|A0A1H5VSY5|A0A1H5VSY5_9BACT Universal stress protein family protein OS=Bryocella elongata GN=SAMN05421819_1297 PE=4 SV=1 +--YDRIAVIYDDSPESTRALSAALPIARMFNATLEVIVMmartpAYTAYAQAVIPeagellaedriasygglqeRAMKSARDAGV-EPEFHLFESDEHHDVITRLKDSKTALLILGLHHKGPVISRLWRSVY-SFAEDAPCSVLGVH-- +>tr|V5XJR2|V5XJR2_MYCNE Uncharacterized protein OS=Mycobacterium neoaurum VKM Ac-1815D GN=D174_16925 PE=4 SV=1 +----PIVVGIDRIYDPTSALTSAFDVAQRKAVGVVALHRGDAERAL------------lREFqqrfptVPTvwSCLRSHRRYQAAAIEECS--RAQLFVVPAGCMRGM----AGRVVMNVVHQARVPMVSVT-- +>tr|A0A1K6C921|A0A1K6C921_MYCTX Universal stress protein OS=Mycobacterium tuberculosis GN=SAMEA2682775_03682 PE=4 SV=1 +----WIVVRMTDAPDNEAVLEYAAREAKLRQAPILALGGRPEELREIP-----DGEFErrvQDWhhrhpdvrvypit--------------TLPD-------------------------------HHSHGYCPVPGRP-- +>tr|S9QF85|S9QF85_9RHOB Universal stress protein family 4 OS=Litoreibacter arenae DSM 19593 GN=thalar_02482 PE=3 SV=1 +-PYARAVVATNGTDEALDLMRFVSQQLPGVKLRLLQVVHIPRQLKEAMLRTGAGKVafadhreqlilkaeehlRllVSKsDVSIQPAVAKGDPAKTLVAYCQDQNMDLIAMGQARKNLVSRAFIGSVSRRVLRDADCDVLIS--- +>tr|A0A117LBZ9|A0A117LBZ9_9BACT Universal stress protein family OS=Thermodesulfobacterium commune GN=XD67_1102 PE=4 SV=1 +----RLGCLIDFSETSKSCLKMASLLSKKDVLEISCLNVIQPPDFLKKTVltsdliEEEKEQRYALWkkli-ANFSdeqdfvqkikfEVMVGNRLEKIEEFVKNQPIDLVIMGKKGKMVQKG--LGSIAREVVRRIEIPMLIVD-- +>tr|V4Y949|V4Y949_9ARCH Universal stress protein UspA related nucleotide-binding protein OS=uncultured archaeon A07HN63 GN=A07HN63_00943 PE=4 SV=1 +----RAIYATDLSAASEAAIENetcLGCLD-RIGIEEIHLVTVIPSNMHVgmpgmkykerrqaGLDRYAGVMEAAGFD-TETHIMRGKPFRRINGLAESEAADVTIVGSRGQSPLENRVIGSTARNLSRTTVVPLLVN--- +>tr|A0A1F9PAW1|A0A1F9PAW1_9DELT Uncharacterized protein OS=Desulfobacca sp. RBG_16_60_12 GN=A2139_05820 PE=4 SV=1 +--FKTIVLATDLSSAWDEIVACAGEFKALGASEIILThvitVLFLGGMDGalraeaqPKLEKQKQFLQGQGFKVSVEMP-VGLPAFSLNDVALRHGADLIVLGSHGKSLWREAVLGCFTCAVLYHTQYPTLLLN-- +>tr|A0A1V4Y4N1|A0A1V4Y4N1_9DELT Putative universal stress protein OS=Syntrophus sp. PtaB.Bin075 GN=A4E74_02028 PE=3 SV=1 +--YEKIVVASDLSEAANHVINSIQDLKKFGTREVILFhalgIRHFHALQYdlarfaePALAEQEELLRRSGFSVKVAIG-PDGVVRELQKVVEEEKASLVVIGTHGRGMAFDALIGGQAHKIMHSATFPLLVIR-- +>tr|L0GXL2|L0GXL2_9GAMM Universal stress protein OS=Thioflavicoccus mobilis 8321 GN=Thimo_1966 PE=3 SV=1 +SLYQHLLLAVDFAPESEPVVARAERMRDRFAARLTLLHivesvpTAieyMPMSYssdgilpdgLELEGELLRaaRTQIDaVGERLGVppgdrLIKIGTTGYTIDETAAELGVDLIIVGNKGRHGLHALLAPSTSKAVLRAQNCDVLCVHL- +>tr|A0A1M7Y8Y9|A0A1M7Y8Y9_9DELT Nucleotide-binding universal stress protein, UspA family OS=Desulfopila aestuarii DSM 18488 GN=SAMN02745220_02698 PE=3 SV=1 +--MQTILAAVDVSRAShlaFKqalvlassmrAELVTVAVTPRyeGNMNRLTLkdad-TKMSVPFLKCLEDAADYAASLGLKIStvHR---VGQPSEEIVRVAEEVNAKYVLLGSPHRSQVERVLLGRTIAKVIEESPCDVLLIPE- +>tr|A0A126ZC68|A0A126ZC68_9BURK Uncharacterized protein OS=Variovorax sp. PAMC 28711 GN=AX767_10525 PE=3 SV=1 +-HYKTILAVTDLSASGNEAVQRAAVVAANCGAELRLMYVpvadnpVWPYYGAHLSELARTVASAAGLSVRV-ARRCGASPEDI--AAEANCADLLVSTYRRERQVGTFFKGEWHQRVMRLTRCPLLLTR-- +>tr|A0A0A1VKM0|A0A0A1VKM0_9BURK Uncharacterized protein OS=Acidovorax sp. MR-S7 GN=AVS7_03454 PE=3 SV=1 +-AYAHVLVAVDFSAASDALVRYAGGLEAAAAVELFHAADRRcESTAqaLRDYRhevrrQAQGRRVRLsDVFEARRNRvgmavGAGDRARQLAVQQESAGADLVALAHRRRGLLGDLLRGRATRRVLDGVGCDVLVYP-- +>tr|A0A1V2NLN6|A0A1V2NLN6_9MICO Uncharacterized protein OS=Microbacterium sp. CSI-V GN=CSIV_07420 PE=3 SV=1 +---EKIVLGVDDSAAARSALAWVVDRCIQRAAEVDVVhvVGPAEAHttpQQDPLANARRVLRAAVpEQSATCHRAQGGVAKTLAGVS--AHADLLVIGVDPEHPIRAALGGWLPVRVIARTEPPVCIVP-- +>tr|F5SM83|F5SM83_9GAMM Universal stress protein UspA OS=Psychrobacter sp. 1501(2011) GN=HMPREF9373_0166 PE=3 SV=1 +---ESFMIAFDGSETAKRAVQIICDNEIAKnlVGHIVMVDNKDT-ANETELYKAHKKMSDEGFN-ITAHLIdskkIGDgdVVSALTSFRNDHNISIFVIGAYGHSKWRRFFVGSTTTKLLTKTTAPVILL--- +>tr|A0A0F9R2J3|A0A0F9R2J3_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0629130 PE=4 SV=1 +---RHLMLAYNGSPLSKKAIDIINKDMFsTQslNIHIVSVQKNNE-DAQQLVNEVETALSSSKCI-VKTTALTGDPLVKLSQYQQEHHIDLTMMGAFSHGKIHGFMFGSFTTQMLLDGDSNYFLL--- +>tr|F5SQ36|F5SQ36_9GAMM Universal stress protein UspA OS=Psychrobacter sp. 1501(2011) GN=HMPREF9373_1169 PE=4 SV=1 +---KTALFGFDNRPTCHALLDWLCSTSLVRnlNLHVVMVGEQTE-RNKEALREAYARLTQSGIS-CKKALIEGRdVTAALMFYQQHHYLEMLITGAFGESRLHELLHGSNTRKLLKASRTPYLLY--- +>tr|A0A0D7F665|A0A0D7F665_9PSED Universal stress protein UspA OS=Pseudomonas oryzihabitans GN=UM91_23195 PE=3 SV=1 +---RQFTIAYDGREATHQGILALARSPLLAgmSGTLLRVGEDDP-ILRKRLDDLALLLRSAGCR-VDTTVAHGDv-ERIVPRHLDERRADLLIMGAYSHSSVWRFLRGSRTTQLLHKTEVPMLLL--- +>tr|A0A1F4MNE1|A0A1F4MNE1_9BURK Uncharacterized protein OS=Burkholderiales bacterium RIFCSPLOWO2_12_FULL_64_99 GN=A3G29_17740 PE=4 SV=1 +---SAFALAYHGGPESLQLVDAVAKCELLHglPCHLVHAGARNA-DIQAEMTQAAQRLADAGVS-THIVIES-GdVEQVMARHLTIQQLPLLVMSAFTHTGWRQKLLGTTTSTLLRRTPTSVLVL--- +>tr|A0A142Y2Z2|A0A142Y2Z2_9PLAN Putative universal stress protein OS=Pirellula sp. SH-Sr6A GN=VN12_15620 PE=3 SV=1 +--ELRICVGIDDSDRSSNAFSKFCEAGWTVPAQVDFVGVVRLPYTYSdipIAIDtsnskksmqaklaqTVVQCQHRFPAA-SIHVEEANHVgDTLVRFATKHHSDLMMLGDTGKGLMGRFLLGSVTRYVLRNAPCSIWISR-- +>tr|B4U6G6|B4U6G6_HYDS0 UspA domain protein OS=Hydrogenobaculum sp. (strain Y04AAS1) GN=HY04AAS1_1621 PE=3 SV=1 +---ENIMICHDGKDEDDKLLDFTKNLNNVYNAKIFLYHADEFGSKkEKLEKLS---K------DYSFelIVEKAIAEEGIVSNAEKLKIDLVIMGSHKK-KLVHFFMGSTTTFVFHYIKTNILVV--- +>tr|R7IIC3|R7IIC3_9BURK Universal stress family protein OS=Sutterella sp. CAG:351 GN=BN620_01779 PE=3 SV=1 +---LRVGVAVDGSAYGEAAVRYTLKHRKlfGDHASFTIINAvndYrgaamtnvtgIALPTlsdkdIDQLEkNefedtvskVRPIFAAEGI-TPDEVKLVGTPADEIAAYARANGIGILVMGSHGYNRLKTAVMGSTAAALAAHGIVPLLIVKS- +>tr|A0A1D2SH06|A0A1D2SH06_9BURK Uncharacterized protein OS=Lautropia sp. SCN 69-89 GN=ABS56_09975 PE=3 SV=1 +--INSVLLPLDGTQVSEAMASQAAGMAQWLGADLSLVQAISPEArpgadipvgdvmESSYVRGRADDYRtRYGV-RTSWEVLHGDPADAIARYLDGRRDVLLAMVTRARRPLEAAILGSVTAGCLQKCGVPIVTRLP- +>tr|A0A0B8QKL0|A0A0B8QKL0_9VIBR Universal stress protein E OS=Vibrio ishigakensis GN=JCM19241_3560 PE=4 SV=1 +----------------HRMVRKTLDLAERLNATPHLVNSYPITPPNITVelpefdptiysdsvrghhlKSMKPFAKSMVSMKSKPSLSKAYHKM-------------------------------------------------- +>tr|R5ESS3|R5ESS3_9GAMM Universal stress family protein OS=Succinatimonas sp. CAG:777 GN=BN779_00568 PE=4 SV=1 +----------------LRLLREAQRLSLFTGCKIALINAITPIIPPVAVdlpgytpdsvydnalkegcKRALSFATRHKIAPNDCHICEGNLDDVIYDECKKLNPTALFIGTSARKGIASALIGNICERVSDNLSCDVVVIT-- +>tr|Q1N6N3|Q1N6N3_9GAMM UspA-related nucleotide-binding protein OS=Bermanella marisrubri GN=RED65_09214 PE=4 SV=1 +----------------EHIFEFSELLNKDNLYKVHLVNSYP---imSMALAslpdtpipedlqqyvleqheEASRELAEKYNIANDLIHIREGEAEEVIIQLTQETDADVVLIGLLAEADFQSVILGSTLEHVLDNTSSDVLGIK-- +>tr|H1Z207|H1Z207_9EURY UspA domain-containing protein OS=Methanoplanus limicola DSM 2279 GN=Metlim_2296 PE=4 SV=1 +-LFRRVLYLTDFSEEAKRCIPFIEWMASAKPDQLVILhvqDTRRLWPatqeqinefnekDTRRLAELKEQMNNYGISQIVTELVTGNAIDEILGVADSFKPTIIVMGAKGRTGALKALLGGVAEAVVHRADAHVLVVR-- +>tr|S6BXM0|S6BXM0_9GAMM Universal stress protein A OS=endosymbiont of unidentified scaly snail isolate Monju GN=uspA PE=3 SV=1 +--FKKILYPVDLAHveFAAGFASEVERVAETFGAEIEVMTvmpgfgmaivaSYFPPDAEQRaRREVERQLGEFASSAFSRpvkiRVEQGTHWKRILSVAKEDAVDLVIMPHCDKGWAESVLVGSCAQKVAERAPCSVLLLR-- +>tr|A0A1E5SUY7|A0A1E5SUY7_9BACT Uncharacterized protein OS=Fabibacter sp. 4D4 GN=BFP97_15930 PE=3 SV=1 +---KNIVVPIDFTKQSVTALENAIHMAERLEMGIILMHSLELpAgfstspvvGaNYQNLHVQRDAAQERlhdlikevaIDSNMNctTKVTYGNLSHAIKRITEEHEIGLVVMASSGKSGFLENLTGSQSYNVAKHVDCPVVVL--- +>tr|A0A0M6XRY6|A0A0M6XRY6_9RHOB Uncharacterized protein OS=Jannaschia rubra GN=uspA2 PE=3 SV=1 +---GPIIVATDLSPRSDRAMLRAARIAKEQDAPLHILHILdeeLPAAILHGHAEDaKKTLQsrvdqTPEIADRspRVDIEVGHLSRLLPGILSDRKPGLLVLGSHRDRGLAELIGQPSLSRIMAVSDVPILLAV-- +>tr|A0A0P1IGI4|A0A0P1IGI4_9RHOB Universal stress protein UspC OS=Phaeobacter sp. CECT 7735 GN=PH7735_03621 PE=3 SV=1 +-DYTSVLGLVSYSRACATVVDAALTLAPEAEVKAIHALHvpyaGLTGGDTDsemakaVRQEAEAEAAKWLEtvpsenDNFEHTIVTGGLRGILMQTVADTKPDMLAIGAHTRSGLFLHRIGGFAAELVREPPTDLLIAPPT +>tr|A0A1G7QRK9|A0A1G7QRK9_RHOCA Nucleotide-binding universal stress protein, UspA family OS=Rhodobacter capsulatus GN=SAMN04244550_03263 PE=4 SV=1 +-DYARVLAPVCFSPSCASALMAVRAIAPRAELRSFHAVPipfsGLTGDGPGsamareLCAEATAERDRWQAsfdqrpDPINIEIISGYLSEI-MARLTVDRPDLIAVGAHTRSGFVPNVLGSFVTDLIVTPPCDVLVVRA- +>tr|A0A158CY26|A0A158CY26_9BURK UspA domain-containing protein OS=Burkholderia sp. LMG 29324 GN=AWB81_04516 PE=4 SV=1 +FSIDRILLCYDGTASGQASLRCGSALVRQLNAEAHLlavlecccgaGGFDPLPAvefdldektAMAILHEGVERLRASTAAAT-GHLLLGNPVDEVSRLANIVRADLIVIGQSPGSAFARGWTSDNSTLLLRRVTCGVLFESA- +>tr|A0A158I9T3|A0A158I9T3_9BURK UspA domain-containing protein OS=Paraburkholderia sordidicola GN=AWB64_05753 PE=4 SV=1 +FDYRRILTCYDGTAEMTAALHHATSLGKSLAAELHVlvvidtaamvaSTLGMPSEgaylniehaARETLRRGLDLAEERGMDAH-GHIAIGNIADNVQHYAQALHADFVVLGHRRRSAFARIWHGPAPhQTLIGRCGASAVITVT- +>tr|T2G9V6|T2G9V6_DESGI Putative UspA domain-containing protein OS=Desulfovibrio gigas DSM 1382 = ATCC 19364 GN=DGI_1090 PE=4 SV=1 +--PKTILWPTDLSSESIASAPKVMALSQQYNAAVVMLyvavdlCSYFPAYGnFPsnevvdhfrlwEIKHARALMEDvcekdfKACPHLELELANGDPVEEIFKMAARKNADLIVMTATHGRHGKDgPGLGHVAEAVATRGALPVLFVT-- +>tr|E9TN36|E9TN36_ECOLX Universal stress family protein (Fragment) OS=Escherichia coli MS 117-3 GN=HMPREF9542_05267 PE=3 SV=1 +-MYKTIIMPVDVFEMelSDKAVRHAEFLAQDDGVIhLLHVLPGSASLSLHRFaadvrrfeehlqHEAEERLQTMVShFTIDPsrikqHVRFGSVRDEVNELAEELGADVVVIGSRN-PSISTHLLGSNASSVIRHANLPVPVVSM- +>tr|A0A0S8B2P1|A0A0S8B2P1_9BACT Uncharacterized protein OS=Gemmatimonas sp. SG8_28 GN=AMS20_06300 PE=3 SV=1 +--GEAVIVGVDATPAGALAAATGWTVARAAGVPCRVVHVtptPSAAPRGgiepaqpdlidGLIADARSHVvdalSGHVPDDVLqtIEVLVGNPAWELRRVVADTSAGLLVLGGKHHAPPVRWFGGSTAHNAVRTIDVPVLVAA-- +>tr|A0A1Y1I1X5|A0A1Y1I1X5_KLEFL Universal stress protein family protein OS=Klebsormidium flaccidum GN=KFL_001700170 PE=4 SV=1 +--ARTVLCAIDGSEHSHRAFHFALHkIICGPEDRVILFHALKPLNIFnhpvilnmtteerAAVVRQSEAaARES-LKVFQEraastgvrtelVVVVGDPREQVSKYVSEHPVDMVVLGARGAADsstpphNNRFRLGSVSSHLVQHCPVPTVVVPE- +>tr|S6A802|S6A802_9SPIO UspA domain-containing protein OS=Treponema pedis str. T A4 GN=TPE_0483 PE=4 SV=1 +-LFQNILVIITGSEASINAAKYAILMAKLYRCKVHAIyvvdTATIKqltlNRIFieeegleyknslqetgsRYLSYVHELGAEKNIE-VITEITQGSVSAEVLNYADKHKIDAILLACEDAQTDns-KDMLAKTFHSILTNSECSLLLVN-- +>tr|I6XYH1|I6XYH1_PSEPQ Universal stress family protein OS=Pseudopropionibacterium propionicum (strain F0230a) GN=HMPREF9154_1950 PE=3 SV=1 +----LIGVGLNTSRVNHSTLAAAFEQAQLLGARLEIVHALQPP-IGLfgpklgpadleeLIRFTRGGIEAMaseqiktfPGVPYEVVVVAATPINEFVTRSE--NYDLLVLGA-GEEAIPGFGLGGLLRGLMAHSLCPLYITH-- +>tr|A0A0A2HQW0|A0A0A2HQW0_9DELT Uncharacterized protein OS=Desulfobulbus sp. Tol-SR GN=JT06_18760 PE=3 SV=1 +--FSCPMLATDWSEPSENALDALLAMKgvtqrviVAHNIDSKLTKNRSKTDIRGLeeesrkrLEKYCDTLKKNG---LTAEPHlsFGHTATEIIRLSREHRATMIILGRTGKDWFQEYWFGGVSHRVAENSELPVMLVP-- +>tr|A0A0F9YCL4|A0A0F9YCL4_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0106340 PE=4 SV=1 +--MEKIVVAIDDSEGSFLALTFGQRFAAQLGADLNAVSVVPTqGDTAARLSTLQARIAVHHLGAVTLDVVNHHSAkEYLGELA-SDEDVGLCMMAHGRRPVSEMLIGSVTAGVVRRALRPVYLC--- +>tr|A0A085WLS5|A0A085WLS5_9DELT Universal stress protein family protein OS=Hyalangium minutum GN=DB31_7875 PE=4 SV=1 +----VAMVGVDASDEADGSVAFIRALREVGPCDVIATYVCSPAEErtrlgihspvrvelldpvvrgiqaldpyveRVLVREVRERLGEVpGEGNVEIHlePGYGRRDEHLLHVARKRGVDLVVVGTHQR-VGLQRWWHgSVSAGVMRHAEQSVVCVPA- +>tr|A0A1S2VCB0|A0A1S2VCB0_9BACT Uncharacterized protein OS=Arsenicibacter rosenii GN=BLX24_25335 PE=4 SV=1 +-----ILLASDFSDASEHAFRYALNILGYVPCDCTLLHAFPiqletaHTPFY-EADIVQQRSLEMlstLGRQLKAERnyrwhrfapqtYPGNSLSAIQHASGQEKYDWIIVGASGRG--LNPWLGSTSSNLLREARTNLMVVPA- +>tr|A0A087BDB4|A0A087BDB4_9BIFI Universal stress protein OS=Bifidobacterium merycicum GN=BMERY_0504 PE=3 SV=1 +----DIVVGVDGSDESFAALKWAMREASLTGQNINavFGWTHSwdtnsdepdseeswahvRHEIADELRSWVEQASDGidfDPERLKMTSVRASGTSALLQIGK--DSQQIVVGRRSLGRVTRWFMGSLSASLAETAQVPVTVVRI- +>tr|A0A0P7YJL7|A0A0P7YJL7_9ALTE Universal stress protein family protein OS=Marinobacter excellens HL-55 GN=HLUCCX14_01565 PE=3 SV=1 +-----ILLATDGSKASFNAQTAFEKLMANQRAGRVVWAHSEQPEQSdeATEQQINELAERLP--NVHRNILIGRPVDQILQTINDTRPLLTIMGKRGSTPIQEIMIGSTTEHVAAASPYPVLMM--- +>tr|A0A0G3M6N9|A0A0G3M6N9_9FLAO Uncharacterized protein OS=Chryseobacterium gallinarum GN=OK18_08285 PE=3 SV=1 +----TIIVCTDFSQEAENATHYAASMAKENEYTLILFTLQSVSIhalnaqasaefFYAQTLKNQKKIADKAAElsdlyriPVNHHLASGNFIEELQNAIHTHNGDFIVMGMTQ-KTIEQKLLGTLVGQTIHRIEKPTLII--- +>tr|A0A218ZRR9|A0A218ZRR9_9EURY Universal stress protein OS=Thermoplasmatales archaeon B_DKE GN=B2I17_09550 PE=4 SV=1 +-----AIIAFDDSDAARAALKFSMKFKDVIDEIIVVyvspsligvtptFDTYIPASVYQrqeetsdsIIESAKSIMGNTSSKITFV--NIDSKgetvPRAIMRTAKERGVDLIITGTRKLSGLSKAILGSVSSEIVKLSTIPVLITPPV +>tr|K0NJN0|K0NJN0_DESTT Universal stress protein family protein OS=Desulfobacula toluolica (strain DSM 7467 / Tol2) GN=TOL2_C19120 PE=3 SV=1 +--FSRIVFGTNFSEASMAAFEFAYQLADYIGCKLHIFHALNLDSsgtqnvlgqkqIEDQIQEAKNRIDQEYVSQMHNFDnydiavWEGSPYIELLKFSREARSDLIVMGHNNMYSdPDEVSFGPTIEQVVLRSACPVISV--- +>tr|K8ZMD8|K8ZMD8_9ENTE Universal stress protein family OS=Catellicoccus marimammalium M35/04/3 GN=C683_0484 PE=3 SV=1 +SKYKNILIAIDGSEMSDAVMEAAKEIIHEDSNVYVETIVDYPGTLGAInedaiiesdyekaekdLAEIIARHpdLKLLVKSFVAEVQVGNPHKMLaREIPDELGIDVIVIGKTTKTSLMDKiFIGSTAKAIVADARCDVIVVKT- +>tr|A0A179D327|A0A179D327_9BACT Universal stress protein OS=Thermosulfurimonas dismutans GN=TDIS_1490 PE=3 SV=1 +-----ILVPLGKDGSYEALLNFVVCMLKGLPegiVKKVyllhvVSSDALKKasrrdlrleslvkdskllkelyqeylkkEAEPFLAEASEKLKKELPNlPVEEVVLSGDPPAEIARFAYEKACGAEIIARRARSHISEIVLGSCTQALIHRPG--------- +>tr|A0A1B9F883|A0A1B9F883_9DELT Universal stress protein OS=Dissulfuribacter thermophilus GN=DBT_0609 PE=3 SV=1 +-----FLLPVDVKKPSYRVAGLVGCLAANLGqrLDSItiltvMAGSYLTShiknidiradrllnsdlikdlrkqhiekEVLPILHEIKEKLVSAGASsPIDEKIEDGDPVERITQVAKEGGYTQIFLERRGVSTAQEIFLGSVSAGLLHKDI--------- +>tr|D2S7D8|D2S7D8_GEOOG UspA domain protein OS=Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20) GN=Gobs_0660 PE=3 SV=1 +-----AVIGLGEHEDDEPVALFAAEEALRTGRPLLVLHTRSDDggeW-----AADSPRWAErWPDLRLTHTPVPGPTGGRVLAAA--CPTPLLAMTAGHGg---lLHRPMDGLHRWLLRHCTSPMAFV--- +>tr|A0A090J5C6|A0A090J5C6_9BURK Universal stress protein UspA and related nucleotide-binding proteins OS=Paraburkholderia glathei GN=BGLT_01853 PE=3 SV=1 +IGFHRILLCVDSTTVVAASAMLVRTLAGTGAQVQIVGVLENARAAIPlgpladfnqnaaharLLREVNARVAEACQLvnesgaAVFTKVvdliaDGGDAAHAIANAAQTWEADLMILGARHHRGLVRWVERAAGAPDMRIGGCTILVV--- +>tr|R7X7A2|R7X7A2_9BURK UspA domain-containing protein OS=Pandoraea sp. SD6-2 GN=C266_02276 PE=3 SV=1 +-------MAVDPAGASQNAVAYTTRLCTHETQVLVLGFFEDPAAFLAphsrtpadmrqafneLQEDELLALERAKVAlqrsgaSVHHRLlgralGNRDISAGIGRVSNEWNADLVVVGAEPADGLIATLTTRVSGVLAEHTHRAILVI--- +>tr|A0A0L0SHN6|A0A0L0SHN6_ALLMA Uncharacterized protein OS=Allomyces macrogynus ATCC 38327 GN=AMAG_07281 PE=4 SV=1 +---YVVLTAVDASAPSWHAVDFAANLVAHLSNYRLLVVYVTAlNRTSRfpyldhldkaynleiqhEAKSAIQECQAYLHRfddnvsyELIEIEGEGEVGPLLEKYIDehVPDCNLVVLGTHGHQGLKKMLYGSVSEYCITHLRVPVTVVK-- +>tr|G2LLF9|G2LLF9_CHLTF Universal stress protein UspA-like nucleotide-binding protein OS=Chloracidobacterium thermophilum (strain B) GN=Cabther_B0433 P +-----ILVGVDETPASEVVVAALAARHFPPQTQVKLVTATGVFeyfssdilgssvavvpsdtidelrRtAAEAATAVQEKLLAaypdWKVTLSREV-IEGDPKSVLLDIAEKWPADAIMLGTRDLSGAERFFIGSVSSAIVAHAPCTVEVI--- +>tr|E6YSA7|E6YSA7_9RHIZ Putative universal stress protein OS=Bartonella sp. AR 15-3 GN=BAR15_160083 PE=3 SV=1 +---QRILIAFDGGPLIMKAIDFICTQEFFKNVTFILGMAEQQIQiIQNSFDETLARLQSAGF-NAEPLRTEINFEQMVLHNIEPLNLNMLIMGAFHRSKVHNFLFGSKSQAIIHNTPIPVMIM--- +>tr|A0A1R0F8Y9|A0A1R0F8Y9_9RHIZ Nucleotide-binding universal stress protein, UspA family OS=Bartonella apis GN=PEB0149_007980 PE=4 SV=1 +---KKALFLYDSEFKWKLITDYFNHFHLFSDKTIVLACSKYASSsVSEDIEKLVRELASAKI-QVSPLLLDDDRDGENInRIVDENNIDMIILSAFNKDKITSLIYGSIPGSLIQKLKVPTLIV--- +>tr|Q2FQE4|Q2FQE4_METHJ UspA OS=Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1) GN=Mhun_1767 PE=4 SV=1 +--FSRVLVPVDLTPESWTAVEQLAKIPDVGEIIVafVISRGETERELERIRIQAEQDIQERCKQiqtagaEIRHRILEGDLVSRILDYAQEADVSLISTVPTEKGFFAEMLHGSFSCELARLATKPVLVI--- +>tr|A0A1V4ZVQ1|A0A1V4ZVQ1_9EURY Universal stress protein OS=Methanoregulaceae archaeon PtaU1.Bin066 GN=A4E41_02078 PE=4 SV=1 +--LSHLMVCTDFSRPEIVSLSM-EDLPFASRVTLlhVVSTGDTREEVNLHSSDAWTRLKELREAysrlkiPVRATVCEGDTAEEIIRHARENQVSLIVMKSSGKRGFIRNFIGSTTTHVTRNADIPVLVL--- +>tr|A0A1V6AR50|A0A1V6AR50_9BACT Universal stress protein UspE OS=Bacteroidetes bacterium ADurb.Bin145 GN=BWX96_03333 PE=3 SV=1 +--FTNVMLCKDFSSPGIEDLCM-DIYPYVTSVELfhAVTRGDSEEEVNHAVKDAKEELEKVAITcngkdiTCNIHVRVGDAADEIIRFSEEKNISLIVAKSTGRQGIVKKIVGGTTEAIARSARKPLLVL--- +>tr|A0A1M3FT72|A0A1M3FT72_9SPHI Uncharacterized protein OS=Sphingobacteriales bacterium 46-32 GN=BGO54_00150 PE=3 SV=1 +---KDVIIPVDFSETSLHAARYAAAMLSGRTDTRVILYHMFEEEAeadttEQYLQTLKTELEQKGVSNIECVKELgDDLIDNLGRLAYQKTAELIVMGITEKEEWRQIFSGSKSLKMVQQNVCPVMII--- +>tr|A0A0Q5ADI8|A0A0Q5ADI8_9MICO Uncharacterized protein OS=Rathayibacter sp. Leaf294 GN=ASF42_13820 PE=4 SV=1 +----TTLVAWAGTTAALTALDWAITREYLLDHHVILCHVAAPADERaiskaALDELAATLQQDRAGIRFSAELLHGDPVEQLERRC-RQDGTLLVVGTDTRNEHSGRFENSLGMRITQRGEIAVVIV--- +>tr|A0A1B6XIQ2|A0A1B6XIQ2_9MICO Uncharacterized protein OS=Plantibacter sp. H53 GN=A4X17_00375 PE=3 SV=1 +----QTIIAWDGSDAARRASTWAASRAAATSDALRVVQVVDRSSA-ddgesleravaSTEDEASRLRVLHPELLVRADVVIGDRYAELRGF--SDDTRLVALGTDEYGSPTRSSGWSLGSRLAAASSGPVAVI--- +>tr|A0A081G1I7|A0A081G1I7_9GAMM Universal stress protein F OS=Marinobacterium sp. AK27 GN=ADIMK_1095 PE=3 SV=1 +-----IPMDPDHADLFDAQVKAAQRLLA-DGGTISTIYVN---QNYVhhvlaatssdrpteieqaILKQVKALFEAEVPKEqrGHVYSRRG-VvHDEIIKKAKAIKADLIIMAAckKPLERY---FLGSNTRKVMMDASCSVFVQ--- +>tr|A0A0W0Z2S2|A0A0W0Z2S2_9GAMM Universal stress protein family protein OS=Legionella shakespearei DSM 23087 GN=Lsha_0702 PE=3 SV=1 +---KHIVIASDFSKYAEYALQRAISLAERHHIPLHFIHVLQQPLSVDFGQylseqpkdflSLEKEMLDKLSVLIMKYPtnvsvnlsvLAGRAADEITQYTEQNQGNLIIAGAQGQYYINEYVLGTTSSHLIEQGKTPVLLI--- +>tr|A0A068NY33|A0A068NY33_9BACT UspA domain-containing protein OS=Fimbriimonas ginsengisoli Gsoil 348 GN=OP10G_3231 PE=3 SV=1 +----RGVFAVDHREEPEEFVDALLQLKPGGIGCLDVLTINEAGHRELASVSRLPAPVADVCSWIDegirsknvaladrlsslgadcrAVVMEGDmPACAIAIAANRAHADFIVVGAKRHGFLDRHLGRSVSKGLLASDRRALLVL--- +>tr|A0A136KUB6|A0A136KUB6_9BACT Stress response protein NhaX OS=Armatimonadetes bacterium OLB18 GN=nhaX PE=4 SV=1 +----SAVLATDHSPYCDACIERFFSWEANGVRRMTVLTSLDRGTAPQQVgPAEASERLTGSLPDVKdqlrarneelclrfrsegieceSVLVEDHPQSAIAQTMSDTEADLLLLGARGHGFWDRIRLGSVSHYQVVATPHNVLVI--- +>tr|I4BYD5|I4BYD5_ACEMN Universal stress protein UspA-like protein OS=Acetomicrobium mobile (strain ATCC BAA-54 / DSM 13181 / NGA) GN=Anamo_1698 PE=3 S +QMARKILVGVDLSKMSESLIAYSHSIAHRLNDEVIYIHVLPRLsSLWrgyepwippQigdeVKQIAHKKIsywiqkaEDQfkdlPVHEHKILIEEGSPGEVIIQKAKEENVSLIIVAYKGHSTMEHILIGSTTTTIARHAPCSVLIYRPG +>tr|A0A0K8QXC7|A0A0K8QXC7_9BACT Nucleotide-binding universal stress protein, UspA family OS=Bacteroidales bacterium 6E GN=BA6E_106139 PE=3 SV=1 +-EIREILCPVDFSDPARRALKNAILLAINFEAKLHILSVFEPFFTTsprfmldsdeeneKLYHefeqRMNQFLGEFDLkrVNHSIEIQKGIPHEKILESIQANGVDFLVMGTNGRSEFSRLIMGSVTEKVIRQLPCSFVTTKT- +>tr|A0A1P8WCF3|A0A1P8WCF3_9PLAN Universal stress global response regulator UspA OS=Fuerstia marisgermanicae GN=Fuma_01329 PE=4 SV=1 +PRFQHILVPVDLTPKNRVALDIAFELATDNKARVSLLHVTQTINtadetlaFYDRLqQRVRDDLeslsqrfSDAGL-AVEVKVPLGQPLKEIVSFAATHQVDLIVMSSHPVDKEdLLQSWGTLSYKVSVACPCPILLMK-- +>tr|A0A0S8KZ47|A0A0S8KZ47_9BACE Uncharacterized protein OS=Bacteroides sp. SM1_62 GN=AMS23_01915 PE=3 SV=1 +--MKNIIIPIDFSEDSLKGIELALLFARKQYTNIQLVYVQKKSSDynspgyfEEENKWAEKKFKeiieRFeprleNDSKLRYIIKSGKIYKEIVSQVESYKEAMVIASTHGASGFEEFFMGSNAFKIISATERPVLTTRK- +>tr|A0A1V6I7Z7|A0A1V6I7Z7_9BACT Universal stress protein UspE OS=Bacteroidetes bacterium ADurb.Bin028 GN=BWX59_00368 PE=3 SV=1 +--MQRIIVPIDFSEESIKGLELGIIYANKFNADLQMVFVQKKKTGrfhielRKQYDAAMEEFEdllrKYkdklhKDCDFSYIIKSGRVHEEVARQAEAFDDSIIICSTNGESGFSDFIIGSNAYKIVQTADRPVITVTT- +>tr|A0A0S8H5N4|A0A0S8H5N4_9BACE Uncharacterized protein OS=Bacteroides sp. SM23_62_1 GN=AMS27_16870 PE=4 SV=1 +-SNLNFLVAFDFRPEAEAALDYALVVGRKIKTDIHILYVLEEESPMlKmvltdaqrkMlQRGAKDNLNDiikqksanQDI-KLYPVIKKGKVYNRIVETSTELGSSMIFMGRTDSMDMVKNFTGTNTMHIVRNSDIPAVTLKR- +>tr|A0A1F3K591|A0A1F3K591_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWF2_40_13 GN=A2W88_12905 PE=4 SV=1 +-TTNHLLVPVDYSDKSVYGLQMAAKLLKLFGGKITIINVVKGVDPIwTefftdeereSlLAKLRAHLKQfaakyidgQVY-PMDCVVAKGKLCDTILKTAEDLNATYIIMGTSTIDNIKKWIIGTNALRIVTEAKCPVITIKQ- +>tr|A0A1J5APR0|A0A1J5APR0_9BACT Uncharacterized protein OS=Bacteroidetes bacterium CG2_30_33_31 GN=AUJ98_05635 PE=3 SV=1 +-TNMNILVPIDFREQSLNALNIAIGLAKTLKLKISLLYVHQDKGALtSlfsseqtaLfDEAVLEKLQDlakinaekNNV-VIDSKlVHHNSVHTAILDYADKNSTEIIVMGRGQ--KDNDVVIGANTLRILRSSNVPVITVDQ- +>tr|A0A1M6ING0|A0A1M6ING0_9BACT Nucleotide-binding universal stress protein, UspA family OS=Tangfeifania diversioriginum GN=SAMN05444280_11763 PE=3 SV=1 +-MNKTILVPVDFKQPSADAASYGCKMAQKMGAGLLLLYVIDTPGILaQffssgdHlvkvTDEAKEKLIElaksmnskfPEI-KTSTRIARGKPYEKILETCRNEDTRMIILGENHQCGDPEDELGTTVYHVTLKSRVPVLTLKG- +>tr|A0A1V6I4K8|A0A1V6I4K8_9BACT Universal stress protein family protein OS=Bacteroidetes bacterium ADurb.Bin028 GN=BWX59_01356 PE=3 SV=1 +-SKKRILVPTNFTSETEIAFEQSVLFSLKTDADIILFHVIPSLKMInSnssn-IDRVQEELSIlaekyfkeTGK-NAQTRIEVGKVLQQILMLEKEIKPSYIFLGSDVSK----GEVSSLTLKLVNSVECPIIIFLR- +>tr|A0A1G2WGS0|A0A1G2WGS0_9DELT Universal stress protein UspA OS=Desulfuromonadaceae bacterium GWC2_58_13 GN=A2X84_02525 PE=3 SV=1 +-MDDKILVPLNGSSTAIRTVQGIIREKSRFFGILTLLHVIDEEKfsyrmipdFqVemirenarksakHLLEEHQESLQRAGL-RTEIRIVSGSPRQVACRIANDENFSLVILGRRGAGEIRDVLFGTLTNYALHNVRCAVMLF--- +>tr|A0A173MHB4|A0A173MHB4_9BACT Universal stress protein UspA OS=Filimonas lacunae GN=FLA_2887 PE=4 SV=1 +--METIIIATDFSHAATNAALYAAELANALQKELLILYIDTLPVTyadvpiptrlEEMTEMGEMEIKKlqerlilhtTGNISITTEIQMGTFFTTLTSVCERVHPYAVVMGSQGTTASERFFFGGHTVHAMKHLKWPLITVPPQ +>tr|A0A0Q4DRS3|A0A0Q4DRS3_9FLAO Uncharacterized protein OS=Chryseobacterium sp. Leaf201 GN=ASE55_13655 PE=3 SV=1 +-SINTILVTTDFSGKSGNAVTMASHMAARHAAHLILFHTVNNYFMtdrtgkqvissetvQDHYLRAEQSlkdlensLRAqHPQLNIEILIKNDTLIAGLNEIIGLRDVDVVISGTSGTQKLKQLILGSMSYEILTGAHCSVMLVPE- +>tr|C6X5L3|C6X5L3_FLAB3 UspA OS=Flavobacteriaceae bacterium (strain 3519-10) GN=FIC_01253 PE=3 SV=1 +-ILKTLLVPTGFSAKCENALRLAAEMAQRHDAKIILFHVVPLQYLidrtgrqiiggdttQITIEQAAEKllsykeaLVAnHPGLQIETHVKTGMLPDVVNDLTVSASADLVILGTSGEQKWKQMILGSYSYDILRDAPCPVLLVPQ- +>tr|A0A0W0GJ14|A0A0W0GJ14_9CHLR Universal stress protein UspA or related nucleotide-binding protein OS=Dehalogenimonas alkenigignens GN=DEALK_13600 PE=3 SV=1 +MTYSKILIPLDGSESAELALPYAKMLAE-KTTALVLFSVCPEDeLRlcrlnSAYLGIQAGVLAQEGF-KAISHTEPGDLAEKIKDYVANEHVDLITVCRQGYSDLSREE--KVLHN-LVSENCSLILIKP- +>tr|A0A0Q0D968|A0A0Q0D968_9PSED Universal stress protein family OS=Pseudomonas syringae pv. viburni GN=ALO40_04922 PE=4 SV=1 +-MVRSMLYATDLGLYAPYVMQHALALARTFNAGLYVVHVVEPMGLFaesvlqsylgeEalqelhgkgvhaFLEGIEQRmldgFREeLGeghsdLSlIRTVRVVQGEPASVILEQAHKLEVDLLVLGRHSASAQEGASIGRTAARVLQSSGVPVYLVPI- +>tr|K9YFE3|K9YFE3_HALP7 UspA domain-containing protein OS=Halothece sp. (strain PCC 7418) GN=PCC7418_3059 PE=3 SV=1 +-MYRKILVPLDGSKTAEAIIPHVKNLAKHDEATVFFAQVIEPATRSGivnfeqeqeitfkpqKLDHAKTylkswqdQFTEEGL-SSEILLLRGVAVDAIVHAINEMDMDLLAITNQGRSGLKKALYGSVSAALLNCAPCPILVGNPD +>tr|A0A0W0GGR0|A0A0W0GGR0_9CHLR Universal stress protein UspA or related nucleotide-binding protein OS=Dehalogenimonas alkenigignens GN=DEALK_05870 PE=3 SV=1 +KQFRTLLIPVAGGPEDEEALELACQLsRALGGIKLVVTNIISIDRSlpldaeveseiakaEGILARFENLGKKYGC-SLETNLLQaRAVAPAIVDEAIEQKADAIIIGSSYKMRYGEFSLGEVVPYLLQHSPCRVILSHH- +>tr|A0A160VBY3|A0A160VBY3_9ZZZZ Universal stress protein family OS=hydrothermal vent metagenome GN=MGWOODY_Clf415 PE=4 SV=1 +--------------------------mARESKTELHAVYIIEVPLElsleaerpedinkgEEILARIEAIASEEKyK-GLQARFLRaRQAGPALVVESEDHFMDLLIVGIPYDRRFGSCNLGTTASYIFNNASCQVMFWRE- +>tr|A0A150QJG6|A0A150QJG6_SORCE Uncharacterized protein OS=Sorangium cellulosum GN=BE15_29465 PE=3 SV=1 +-AYSRPAVALDLEQGSTEVLALMLRLIPAPRPRATVIHAFDTPY-RgViypsLSEEDAeewrnelgQTATQqiakliaaslaqakvrpAEAPPWKTHVRCGSARLVIEKAVKKADSDLLVLGTHGYSGVAHVILGTVAGDVLREVACDVLVVPV- +>tr|A0A063Y9C0|A0A063Y9C0_9GAMM Universal stress protein family 3 OS=Nitrincola lacisaponensis GN=ADINL_0001 PE=3 SV=1 +-MSIKIILPLDLQdrDSAIAGLVRAKTYLGDRPVEMYFMSILPKPVPllgaylpKEEIASALrvleDEMrllvKQVMpeIGPFFTKATEGVIFKEILKYAREVQPDLIMLPSHSHSKVENILIGSVTSKVVERADCSVLVIR-- +>tr|A0A142HYN0|A0A142HYN0_9SPHI Uncharacterized protein OS=Mucilaginibacter sp. PAMC 26640 GN=A0256_22330 PE=3 SV=1 +--MKKILIPTDFSANATHAAEYGYQLAQQLKADVVLCNAVIIPAeapqaglvvwpmeeTTVLLRNSEvelkklkTSMQQHdhsdKFhPAITYIEQAGMLTDVVNDIVKTQHTELVVMATHGSDSLSAFLLGDHCSKMIDNSLKSLLLIPQA +>tr|A0A0R2VIG7|A0A0R2VIG7_9SPHI Uncharacterized protein (Fragment) OS=Sphingobacteriales bacterium BACL12 MAG-120813-bin55 GN=ABR95_14065 PE=3 SV=1 +--MLKIIAATDFSPASKHALEFIINATSNLQREIVILNVVHLdgpPPASMissIIEslktKAYFDYQslseeimeKYGeHLPMRFHAEVgGPAHKVIEKVARDENADLIVLGMKGMSDMQK-VfLGSVAASTAMHSKFPIMIVPSG +>tr|A0A1H5ZPW4|A0A1H5ZPW4_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Chryseobacterium humi GN=SAMN05421847_2124 PE=3 SV=1 +--MEKILVTTDFSDHSKSGLRFAIQLAAQNDYLLTFLNVHHLqipSAWDVlseneYQDeqkrIVHAKLIqfveniyeAIHlkPKHVQYAVELsPLPESSVLEFAENHNFNYICISARGAGILNK-ILGTITSNLINQSKVPVIVVPHD +>tr|A0A0J8DC56|A0A0J8DC56_CLOCY Uncharacterized protein OS=Clostridium cylindrosporum DSM 605 GN=CLCY_3c01600 PE=3 SV=1 +MKIKNILIPLDESEKTLESVNTVKSLFNHQEVVIHVVHVVNRYKIAlsepsnphedqlkslNILNKAEKMLS--GY-KVNKITQIAtelSIAMDILKVINENNIDAVFMTKTGKGFFDKYIIGSETSRLLKISPVPVIVTP-- +>tr|E7QMJ4|E7QMJ4_9EURY UspA domain protein OS=Haladaptatus paucihalophilus DX253 GN=ZOD2009_00050 PE=4 SV=1 +---MVIVAAIDRTERATDVLAEATILAEKFEEEVHVLHVMKRSEAIQIEEdstnkdeavstaELReqaaQPAKslvdtNPTGVGTTTVGRIGDPASEIVEYADDHQARYVVISPRRRSQTGKLLFGSVAQTVLLNASCPVVSFAD- +>tr|M7NNV2|M7NNV2_9BACT Universal stress protein family protein OS=Cesiribacter andamanensis AMV16 GN=ADICEAN_01422 PE=3 SV=1 +-RLRNLLIPVDFTPHADNALRYAIALARSIPMtRLYILHTYHIPAAVtgagamavapYYESElrqsTEEKfqelearmLKNCRV-PYEFVGEYGPAVPDICEASARLEADLIILPAHPTNRLDEYF-GNVTTATIRSSPVPVLVVPPH +>tr|A0A1G1KNE7|A0A1G1KNE7_9BACT Uncharacterized protein OS=Omnitrophica bacterium RIFCSPLOWO2_12_FULL_45_13 GN=A3G36_05740 PE=4 SV=1 +MAVKNIVVSVAGENGGISTVKYAIYLARLLSSKLTAIYVVNERILNEllvrkifveaeahsyardleersrrLLERVREMAHSKGV-ECETILLKGAIHEEIINHTRAMKADMLVMGELKEVLSLKEIFYDEGERIFREAPCPVVVVKN- +>tr|A0A1V6GAQ8|A0A1V6GAQ8_9DELT Universal stress protein family protein OS=Deltaproteobacteria bacterium ADurb.Bin072 GN=BWX71_02265 PE=4 SV=1 +---MKIMMYYDGTDCTKEALPVVMMRAKAFGAEVHVVAslPSGEEKDLKTIDRmnvdldyIQSVFETQQV-PCETHLlITGrGAGEDIGAFARKHEVDEIVIATDRRTMMERLMANWMARRVMSDTRCPVLLT--- +>tr|A0A1W9IU67|A0A1W9IU67_9BACT Uncharacterized protein OS=Nitrospira sp. ST-bin5 GN=BVN29_17950 PE=4 SV=1 +-KLRRVLVPVSAEYSPQLAIDTTAQLASALGCdnlTVIVVQVGDDRTLHSL-H----YPIKTGW-LWHTMACQGNVVEVILAMGKDFDVDLIVMTTSKQQTLLDLMRGSTTERVLRGARCPLLALPV- +>tr|A0A167JNZ1|A0A167JNZ1_PHYB8 Uncharacterized protein OS=Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC 33097 / NRRL 1555) GN=PHY +-SSRQIVLSIDPlSEEADYTVQWVAENFLRKTDNIYIFMVLVveDDndvsdeleavvFDDgtlsdiqketaaqnsLAMANIVKRLNAKGFNNVSYRIYkamASKACDTLVQYIDSQKTDCLVMGSRSLSGWKRFFMGSFSDYVQSQAKCPVLIVK-- +>tr|A0A0S7YTU6|A0A0S7YTU6_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium SG8_13 GN=AMJ54_04200 PE=3 SV=1 +-KPITILCAIDFSKFSKQLIRYATQLAGRLSADLVVFHSVCFPRsaSQdtaasgqvgdgkEGVQRARELIDELmaGqQLPWRSEIRIGEPVVELKALVRELPIDMVLTASYDLSGWKRLLLGTVVEELAQTLSVPMLVVKP- +>tr|A0A150XJK6|A0A150XJK6_9BACT Uncharacterized protein OS=Roseivirga echinicomitans GN=AWN68_04325 PE=3 SV=1 +-MYSRILVPIDFTEKSHRALEVACQIAKKLNSEVYMMHIVKAALsvyldelgeyksktptGQQFLDDIlslneekmkrlIQKYEDRGI-TIHSKLKVHDTPNEIAKLVAEEAFDLTVVGNYEHERFDEVFKRTHPEKIAALAKNPVLTINN- +>tr|A0A0C5BVM2|A0A0C5BVM2_9ARCH UspA domain-containing protein OS=Candidatus Nitrosopumilus piranensis GN=NPIRD3C_1094 PE=4 SV=1 +-KIKKILIPYDATPSSEKAVKKIFPLIDKDCSKIIFLTCIHDKATFgffktksdrkEMeqekeknkkyHERLKKEADKLGI-QASSKIIkSDLESKSIIEFAKDQNVDLIVMSKSKIgTHAERLYYNSTVDAVFKKAPCPFLYI--- +>tr|U5C5W6|U5C5W6_9BACT Uncharacterized protein OS=Rhodonellum psychrophilum GCM71 = DSM 17998 GN=P872_02975 PE=3 SV=1 +-VPKKVLIPLDFSEHSNLTFKFAQKLFEETNTEILALHIYEVPTGYyktgksyeEfaaIMKgHAKKdyekFLQKYKHQHFECLflMdEKENSGKFITRMAQEHQANWIIMGSRGRTSSASVLLGSVAENLVEaNNMLPMLIFKK- +>tr|A0A150AKP4|A0A150AKP4_9BACT Uncharacterized protein OS=Flammeovirga sp. SJP92 GN=AVL50_12125 PE=3 SV=1 +-KEPKALIPINFSETSKDALQQVEEiAGHIHELKSLAINCFRIPNGYsttgksydEmveILTdVSQKkldhFVKSAVDDhniETKPIlIeEDDTTADAIYKAAKDENADVIIIGSKSRTFMASMVLGSTAEKLLLsDINIPILIYKN- +>tr|A0A1E5T1I9|A0A1E5T1I9_9BACT Universal stress protein OS=Fabibacter misakiensis GN=BFP71_17730 PE=4 SV=1 +-NTTLLHVPCDFSPHSKIAMEEAIRvARKYKNVKIICQNVFTVPGGYhysgktyeEfaeVMReNAMKdyqkFMSEIDHDgiDLEVVysLdTNDNPVTDIIDFAQKNNPGAIFIGVKGRTSTAALFIGSRAEQLIQyNSDIPMMVVRP- +>tr|A0A1Q5PHB4|A0A1Q5PHB4_9BACT Universal stress protein UspA OS=Pontibacter sp. S10-8 GN=A3841_11375 PE=4 SV=1 +-QLRNLVVSTDFSDYSVMAVERVLEiANEKPDIKVVLLHAYQVPTSYrtlgmsykSfdeRMRgFAQAkyekQIQRFPQLqgrAEFALvrLeDEDDIGELVVLEAKRNRADLLVIGAKGMSAAALFVLGSVTEKILRhDLDIPLLVFKK- +>tr|A0A0S2HZP5|A0A0S2HZP5_9BACT Universal stress protein family protein OS=Salinivirga cyanobacteriivorans GN=L21SP5_01849 PE=4 SV=1 +-KIEHVMVRMDFTKIAGITMKMAEQlQEL-TGAKISCHHVYKLPLKYfpqnrpedDeklqmHVEkHSKKeyekFAKRLKIDtkAIPCTwtLdVENEEAHILYNQALNIQADMILIGSKIKSEMADVILDTTSEKLAGpEKNIPVFVVKD- +>tr|K2EYN8|K2EYN8_9ZZZZ Universal stress protein UspA-like protein OS=groundwater metagenome GN=ACD_20C00187G0004 PE=4 SV=1 +-GTKEVLFAVDGSEFSYHAVKQAISILNLDNSAIEILTVMAGAESLpleitmdnEWLqnslrkqkeiaeeilQNTKKLFQDHNIPVKSTVIQEGDASEKILDYLEENRHDLLIMGSHGREGVSDFLLGSVSKRVLDHSISPVLIIPI- +>tr|R7LWL1|R7LWL1_9FUSO Universal stress protein UspA-like protein OS=Fusobacterium sp. CAG:815 GN=BN791_00576 PE=3 SV=1 +-DSKKILFTIDSLDTTPKVVSKCIETMNLSDKDIYLTTVYEVPDYLflegnldsNWIieveqkqekaamlllNQFEKIFIESNLNIKDKVILRGTPAQEIIKYASINEIDLIVSGVRDKKGLSRIFLGSVSKRILENTNSDSLIIRI- +>tr|X1N8A4|X1N8A4_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S06H3_51924 PE=4 SV=1 +-MINKILLPLDCSDVAEEVFPYGEELARKLGCDVILFNACVPEYRLarnmrRlYLKKTaelmQNRLRKYrlkGtGPRVLSEFVHDEFAKGICKYVAANDINLVIMAAHGFTSIRVRPVGSIVDKIFRLLKCPALLVRTD +>tr|A0A090VCV5|A0A090VCV5_9FLAO UspA protein OS=Algibacter lectus GN=JCM19300_276 PE=4 SV=1 +--MKTILYATDCTKNDASALKYAYRFSYIMKADLHVLHVYDFPPIHlsviqpiEklqnrMKQEKKDIVKKfcetHlknefRETPIKIHAVENtSVEDAIIDTAKKLSPDLVILGMKDDHSHRGFFASNIANELLDRVNFPVMMIPNG +>tr|A0A090VXL0|A0A090VXL0_9FLAO Putative universal stress protein UspA OS=Jejuia pallidilutea GN=JCM19301_1083 PE=4 SV=1 +--MKTILYATDCTVNDIASLKYAYRFSTIMKADLHIVHVYEFPPIAnatlhapEllkkrMHIEKTKLVENfckvNlkhefQQKPVTTHVIESgSVSESIQRLSNVLMPDLVIIGMKDHHSTREFFSGNIANALLDTIEMPLLIVPNG +>tr|A0A0U5KCF9|A0A0U5KCF9_9RHOB Nucleotide-binding universal stress protein, UspA family OS=Rhodobacteraceae bacterium HL-91 GN=Ga0058931_0603 PE=4 SV=1 +---MEIMLAYDHSRNARIALDALRDMFGQIKPTITLVSVVEDVGSatsgaddlfNEqyatqkaGVEAAAAELMAEGF-EARVVLAQGDARKMILRATEERKPDLLVMARHShqPDDgplgfiarridalveeFDHMTFGSVSAFLARRAKCPILIIPT- +>tr|A0A1W9LTN3|A0A1W9LTN3_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium IS3 GN=BWK80_53830 PE=4 SV=1 +-QEYDVLVAIDQSENALKVAEYVGKMMRShPTVRVTILNIIRPPSPDimpdreerliyvekkrsdvnALINKARGILMSFGIPetQIFTKIqvceEPVSVADQILHEKRECGYGTIVVGKRGMSKKEEFLFGSVSRKIVRECqKSAVWVVV-- +>tr|Q0W0J6|Q0W0J6_METAR Predicted universal stress protein A OS=Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50) GN=uspA-8 PE=4 SV=1 +-KYGRILIPISGYKHALRAIKMAELLAKKYGSEITVMYVGTEKDdPRQVITPVTSDLKGNGL-KHRAIFRTGPVVETILAEAE-KNYDLIAIGATERQQPYNFVTGSTADRLIKKSSCPVLMIKT- +>tr|S7VU52|S7VU52_9FLAO Putative universal stress protein UspA OS=Winogradskyella psychrotolerans RS-3 GN=ADIWIN_2210 PE=3 SV=1 +-IMKKILLLTDFSKNATNAIRYAMQFFESEKCTFYILYVHKISGYVsddllmspkdsihdSITKKPKeklnaliEKLKNEtktNDYQFEILIDFDVFTDAINQVVKKFSIDFVIMGSNGVSNVKEVVFGSNTINVIEKVNCKTIVIPSN +>tr|M7NCY6|M7NCY6_9FLAO Uncharacterized protein OS=Xanthomarina gelatinilytica GN=D778_02238 PE=3 SV=1 +-HMKHILLLTDFSESAKNATNYALQLFQDQASCFYMLHIPQKSVYTtsdlmaagtssiynSLVKKAKtkldkyvKTLESNssnKKISFETIVDYDVLTDSVNQIISSKKIDLIVMGTNGVTGAKEVVFGSNTINVIRKVDCATLVIPKG +>tr|A0A1E2Z1P1|A0A1E2Z1P1_9GAMM Universal stress protein UspA OS=Serratia sp. ISTD04 GN=BBC05_08500 PE=4 SV=1 +-MIKRVLLAVDCFEHSGNALDFMARLQG-SIGDVIVLTVVDNAFTLsrsglrfdseEreeypaaqreealaekQVGQVTRALKQQGF-NAQGLLAAGTPIEVIPEQMALFNCDLLIISHRHLSSLGRWLNASVTRGLLDEIGQPVLVIPR- +>tr|A0A1Z8M0K9|A0A1Z8M0K9_9FLAO Universal stress protein UspA OS=Muricauda sp. TMED12 GN=CBB72_09850 PE=4 SV=1 +-SLKKILIPFDFSEASINALEYVVNFIGTERsIGILGLYVGNMpiseTDNEKLEKDFSKVMDSfdvKLKIAPEFTTDTGEVIGTILSAQEKSNADLIMMGTMGDKI--TDEAITNTSKLVLKANCPVISVPY- +>tr|B4U9B0|B4U9B0_HYDS0 UspA domain protein OS=Hydrogenobaculum sp. (strain Y04AAS1) GN=HY04AAS1_1035 PE=4 SV=1 +---MKYLVSVDFSDITNLVVRSAKVFATKLNVELELLHIIAPFTYlpyPeglsidivdmDIIKKaeenaknlALEKLSALaeylDPVKTTYKVLIDTPFAEIVSQEA-EnnNMDGIFLGGHSKNLIEKILVGSTTEDVVKNSKVSLVVIKA- +>tr|U1PUH0|U1PUH0_9EURY Universal stress protein UspA related nucleotide-binding protein OS=Haloquadratum walsbyi J07HQW2 GN=J07HQW2_02488 PE=4 SV=1 +HMFETILIATDGSESVRRAVDTGLDMASRFDATVHCLYVIDESDVNtdtqkpgsdhdhdhpAMYehgQEAVETVAERTDGEIITTIERGDPPSVIEAYAGDIDADVIAMGTRGRHGENRFLIGSVAEELVRTVEIPVLTVRQ- +>tr|A0A0U4W0T7|A0A0U4W0T7_9BACT Uncharacterized protein OS=Caldimicrobium thiodismutans GN=THC_0367 PE=4 SV=1 +-GYRKILIIYRNSPE---FLRESFKLAKKEGTWVVVLKPLPTYEGElhltgiknleEILEgyklkeykQIKELTEEERV-LAKIRVEEIEKEEDILDIAIEENCDLIVIEPKKPTLFERLlsLKDRLIELLIDQSPCPVFIIR-- +>tr|F4B076|F4B076_DOKS4 Uncharacterized protein OS=Dokdonia sp. (strain 4H-3-7-5) GN=Krodi_2351 PE=3 SV=1 +--MKHILIPVDFSDQSWNTALCAFNLHKSAGVRFYIFFSEQHDYATgeatvicehpaQQLSSWVKKLEKlkGSGQVIIPLKWESDFISDMRGAVADNNIDLIVMSTHYPNIFCDVLKGSHVREVITRLKCPVLIVPR- +>tr|A0A090PKP0|A0A090PKP0_9FLAO Universal stress protein OS=Nonlabens ulvanivorans GN=JCM19297_807 PE=4 SV=1 +--MKHILIPVDHSDPSWAAVHCAISMHRDAGICFYLLHRESLNLQLdeevvklktdyNTLQARIESTKKllSPHQKLISLSSDGTFIAQVKEAVYENDIDLIVCSDLYPFDQKAKVDLTYTKAIITRVKCPVLIVPQ- +>tr|A0A136JRC0|A0A136JRC0_9BACT Putative universal stress protein OS=Nitrospira sp. OLB3 GN=UZ03_NOB001003104 PE=3 SV=1 +---MRWLVALDESEFSERIIGWMRAFPHSKQTAVTVVHVLAPLDVPEtigltgqqlllqqqgamveaLLQRVRRLLE-ESFADVEVILREGVPSREILQVIQERRPDLVVSGMQGLYRSPGFTIGGVAQRLLSYAPCSLMLVPG- +>tr|A0A0Q5WA42|A0A0Q5WA42_9ACTN Uncharacterized protein OS=Modestobacter sp. Leaf380 GN=ASG41_14210 PE=3 SV=1 +--PAPVVIAVNDRPEGSAALTWGLKRARRLQTTAVLVPSTGDTpsaPVHLsvaTRDLIESATAAAGV-DYVLHEQPEDVAQALITLS--EGADMVVLPVRRRSVTMKFLLGSNAMRVIAEAHCPVVTVK-- +>tr|A0A1N4YLG8|A0A1N4YLG8_9MYCO Universal stress protein UspA-like protein OS=Mycobacterium abscessus subsp. abscessus GN=SAMEA2071243_04046 PE=3 SV=1 +--EKTVVLGLR-EDASENVIAEAVREAKLRQAALRVVMFSADDpssPNYSgvsQVKEIARELIDAGV-EFEIFRPASDVGEQVLELARQHNAELIVLSIRKRSPMLKMLLGSATQHVLLGADCPVLSLR-- +>tr|A0A1V4RTG7|A0A1V4RTG7_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium 4484_190.1 GN=B1H11_10170 PE=3 SV=1 +-LTKRITIPLDGSQNALRSLDYLNFIYGPKhNLEIILIYILPQLPSFmtdktsfdketwirirgveeksiqmaeRILEQAKNVLIEKGFPeeRIKAQYkkQETGVASAICNMAKMKQIDTLLITRRGRSNIKTFFMGGVSKQLLDSCqVCPVWIVGS- +>tr|A0A1V4RTG3|A0A1V4RTG3_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium 4484_190.1 GN=B1H11_10165 PE=3 SV=1 +-AGNKILIAVDGSDQSLYAVRYVSKMMAPKKTEIVLYHSIRKISEAfwemgvkpissqklssiraweisqekkihEFLSLSRQIFLDNGFPeeSVKINIheTRKGIARDVYNESK-SGYTGVVAGRMGLNVLKDLVLGSVAAKLVEKLhDTPVCLVGG- +>tr|M0LXI4|M0LXI4_9EURY UspA domain-containing protein OS=Halobiforma lacisalsi AJ5 GN=C445_00535 PE=4 SV=1 +-TVDTVLAPVDGSDESATAVEYAVAVADRYDADVHALFVLGRGVVRgldagtvdeddvaektqGFFNDIGSIADDYGValstsvdDGFSQTRKTRHPGNVVLDTADELDADFIVLPREPVTEPSAEVLEKAAEYVLSYASQPVLSV--- +>tr|B1X544|B1X544_PAUCH Uncharacterized protein OS=Paulinella chromatophora GN=PCC_0638 PE=4 SV=1 +-MFKNLLIADSDKGHVEDMVRMLRDIPQLSQANLNFLYVVTEQAGEGveeNWKkvadsveVMTKRLGMS-PSEVNVIIRQGDKKQTVLKVADELDVDLIVMSSRGLGRLQSILSNSASQYVFQLSTRPMLLVRED +>tr|A0A1X0UKS6|A0A1X0UKS6_9NOCA Universal stress protein UspA OS=Rhodococcus sp. 1163 GN=BJD99_04455 PE=4 SV=1 +--TAELVVGWDGRPPSTSAVEYAVDLAERITAHLHVVHIVDIDDlpidpdssdYETELRatldeqarHARELLDGLDA-SWTYHAWHGSPADLLDTVADEYKALMVIIGSPRGgfmSFLDSIGGVSVSHRLISRHRHPLLLVPE- +>tr|A0A0P7XIR2|A0A0P7XIR2_9BACT CPA2 family monovalent cation:protein antiporter OS=Bacteroidetes bacterium HLUCCA01 GN=HLUCCA01_03730 PE=3 SV=1 +-QPKRVLVPTNGSKAARNAAEMAFMVGRAlENCEVIAMNVSSNERARlgielqDnRDfdrkkiaHEIVAELKKSGEafgVSTEALVVHGEsPEQAITLVAEENNIDLIMVGTSVRPASSRLYMGPRVENIIQHARCPVVIFNA- +>tr|A0A0S8DAQ4|A0A0S8DAQ4_9BACT Universal stress protein OS=Nitrospira bacterium SG8_35_1 GN=AMK70_10760 PE=4 SV=1 +-DIKRILVVSRSTIDCRKAVHYGVSLSWKYTAELYVMHVVHDPLIfgkwnlpfpsieeeyRNMLKKAKSELNeiitkekSKGL-TIKELIKEGKPSEVVLNAVKEENIDLIIMITHEEGLLEHFIFGRSNKEIVRALPCSILLVRK- +>tr|A0A151ZFX4|A0A151ZFX4_9MYCE Uncharacterized protein OS=Dictyostelium lacteum GN=DLAC_05412 PE=4 SV=1 +---MKYLVCVDGSAEARKALSKAITMVST-EDSMYFLNVYPPLPSEngicpssnctltkmviEmfsgvpdLvdeddpIKQQKKsnkkkslalkefnFIKSQQINekcNVHYlLVASPDISDTITKIAEHYCVDAIVMGCRGLGL-QKLLIGSISSQVLQMSNCSVLIVR-- +>tr|F3Z023|F3Z023_DESAF UspA domain-containing protein OS=Desulfovibrio africanus str. Walvis Bay GN=Desaf_3776 PE=4 SV=1 +GMFTRILVALKYNDTGRHALSVAAELARIHGAELIAFHALDYRLlaegvSaaerDQACDAAHRRFEQeFGpifreGGASDFVCLPADPAMAVCRLAREREADLIVLGCHQRGQGSgLSRMDYTGMTIMDKAPCPVLLVPY- +>tr|A0A1B6Y6S8|A0A1B6Y6S8_9BACT Uncharacterized protein OS=Balneola sp. EhC07 GN=A8B79_11195 PE=3 SV=1 +-KVNRILIPTDFSEQSKSALKLAGFFTKIYGSTIDLIHIVPFSMYmsesmdklglpfdmdkdlyPKVVEKAKSELDELASdfimekYLGKTHVQVdRKPSSAIAEFANKEGYDLILMSAKGAHE-TNFFKGSITDKVIRKAHAPVFTVSR- +>tr|A0A0S8K5M6|A0A0S8K5M6_9BACE Uncharacterized protein OS=Bacteroides sp. SM23_62 GN=AMS26_01970 PE=3 SV=1 +--LKKILLPVNPEYYTRETLDFTIQLAKLYQSEIIPIHIIGKEAEFmsirdiahkiaeEHIKKVQSRIKKEGINTVDPVIDFGNHFDRIAIAALKYDVNVILFGIRIGTEQEGSSLNLNIEKVIRHCDKPVWAVKE- +>tr|A0A0S8A2Z2|A0A0S8A2Z2_9BACT Uncharacterized protein OS=Gemmatimonas sp. SG8_17 GN=AMS18_05200 PE=3 SV=1 +--LETILLTTDFGKGSAPAMDAAVALAQTFESKLVLLHVIAESLLPflsdqgdiaeieKRLHEVAKQIEAQGVGAPEIFLGKGVPAEVICGEAARRDANLIVIGCGARERGGKCRPGVTADRLLRRAITPVWIARM- +>tr|W5H054|W5H054_WHEAT Uncharacterized protein OS=Triticum aestivum PE=4 SV=1 +--GRDLLVAIDFGPNSRHAFRWALAHLARIADTLHLVHAVSSVHNelvYNKSQELMDELAVeaFKEslVHTKARIVEGDAGNVICREAERLKPAAVIIGTRGRSLIQSVLQGSVSEYCFHNCKAAPVIIVP- +>tr|S0G776|S0G776_9DELT UspA-like protein OS=Desulfotignum phosphitoxidans DSM 13687 GN=Dpo_2c03320 PE=4 SV=1 +-MFNKILVPVDIDYPkaSKAVYDNAAELASLSGAQIRIVSVMPGFTMpivasfvtEEIKKQAQAHFQkalddfvAAncKGANVSYKVLVGKHYEEILKMADKWGSDLIVVYHNRNRTVNEAFSSTCAQRVVKEANCSVLRLRN- +>tr|A0A0S7BM31|A0A0S7BM31_9CHLR Universal stress protein family OS=Flexilinea flocculi GN=ATC1_131391 PE=4 SV=1 +-EIKQVVLAFSQSPKAREAMCFADILSKSTNCKISVVISGKDETRrNSAYEEVKKYYIRQNV-EADYFVIDNEPEVAILQTADQIHADLIVMGGFSRSLLQRIFKRSTIDKIFVATKKPVIICK-- +>tr|A0A0C7CIR0|A0A0C7CIR0_9FUNG Uncharacterized protein OS=Rhizopus microsporus GN=RMATCC62417_17281 PE=4 SV=1 +-ESRIVAIAYDYSNYGDAMIAKSIHSDLlRPNDDIRILYVMNQNDYHNlftpmltvygtnrnyddsqdaylrnavdtFMWEIITVLNKRGFHNVSSEILRGDPKEVIVDYCRAVKPVYLLTGTRGLGAVKRICFELLSKALPLSCASD------- +>tr|A0A0C9MT24|A0A0C9MT24_9FUNG Uncharacterized protein OS=Mucor ambiguus GN=MAM1_0127c06026 PE=4 SV=1 +-KRRVVVVAYDHSNYGDAMISKSIRLGLiRPRDDIRLLHIVSQSDYRNlfapmlsatgtsggvhasdldsnmasvadaMIYEVINSLRKIGFSHIKSEILRGDPKESITDYCRMSKPAYLLTGSRGLGAVKRTVMGSVSSYLTKHCPCPVLICKL- +>tr|A0A015IKS6|A0A015IKS6_9GLOM Uncharacterized protein OS=Rhizophagus irregularis DAOM 197198w GN=RirG_231490 PE=4 SV=1 +-KNYNILVAVEETSISNNAIEYAFDLCSRLKdsYSLSIIYVIAlnPEtnvPFLhnldkannlDILLDAkeavnkiREYLKKFdntyPNVQYDliEHKGYGVVGKILTEYISQNQLDlnLLIVGSRNLDGLQKVVLSSTSDYLARHVHCPVTIVKQ- +>tr|D4W223|D4W223_9FIRM Universal stress family protein OS=Turicibacter sanguinis PC909 GN=CUW_0860 PE=3 SV=1 +-MYRNILVAVDDSEKSKLALNSAIHsavvFNSKLTichIKKNTIIYTPidPTgmlstTHIfkqdfsnymDEELEKykemalNQGVKEV------eiVQTYSSSPGLAIAEVIAP-GYEvdLIVCGASNKSGFDRFLLGSVSFDIVKHAKCDVNIIRN- +>tr|A0A1Y1Z5U5|A0A1Y1Z5U5_9FUNG Adenine nucleotide alpha hydrolases-like protein OS=Basidiobolus meristosporus CBS 931.73 GN=K493DRAFT_404268 PE=4 SV=1 +-IPYTLVVALDSGELSRKTANYAIDLVTRLAcpYKLYFIHAIGlnPAqslPFLddldkannyDIEEKGervvaenLKWLEQ-ykNKVQYEwvTLKEAGECGVIIEKYINS-LPHvdIVITGTRNYEGVKKFIMGSLSEYLVHHIKYPVVVIKS- +>tr|A0A1F4RRL1|A0A1F4RRL1_9BACT Uncharacterized protein OS=candidate division KSB1 bacterium RBG_16_48_16 GN=A2V82_10390 PE=4 SV=1 +-FFKRAVVAAAFSPRLVAVLNESQRILKILGAWPIIVHIGEENPS--NRSKLEDAVARSEFrdhPP-VLIVRAGQPSDVLMDVVLEYEADLIIAGALKKERLFKYYLGSIARNLARYSRCSVLLL--- +>tr|A0A0W1RE19|A0A0W1RE19_9EURY Universal stress protein OS=Haloferax sp. SB3 GN=AUR65_05020 PE=4 SV=1 +-TYRRIALLASDAPSSEPTATLARRIAAATRGTLEPLAVVDERDAAiaspetrRALeREARTRVKDvvaaaarDAV-ESGGTVRTGVPTAELLAHVERTGADAVVLGVGGNGrsgrsggdggsdgsdengesgdaprPSEHRATEVVANRTVRHAAVPTLVVPTP +>tr|A0A139GSJ5|A0A139GSJ5_MICAE Universal stress protein UspA OS=Microcystis aeruginosa NIES-88 GN=OA58_06605 PE=3 SV=1 +-KIKKVMVALDKSSSADLALDLAIYLLRDyPSAELILARVNPDLKpefaptspkemeENPILRPAVAKVKRMNI-PYRCLVTGGKPGEQLCKLVDDYNVDLLLLGSPDRRPsvakslpdLDRLLGTSLSDYVRVNVNCPVLLARK- +>tr|Z9JS94|Z9JS94_9MICO Universal stress protein OS=Brachybacterium phenoliresistens GN=BF93_17865 PE=4 SV=1 +---MAVVVGFIPTPVGFAALEAAQREAERRGGPLIIVNVVRDGMQgdprhadQGQLERAQDMVRRASVRiAVRQEHTDDDISDVLLQVVEEEKAELLVLGIRRERDMASHLLGVTVQKLLTSSPSDVLVV--- +>tr|Q55FP9|Q55FP9_DICDI Uncharacterized protein OS=Dictyostelium discoideum GN=DDB0189712 PE=4 SV=1 +---NRYMICLDGSQVSERAFHWLEALAMCDLThqtEIFLFHAVDRKAVtkleldtnpnctrhelaEKALDEYTKSLAVNNVI-SHKLLIdtKESVKDVIIKEIEKNKIDMVVLGHEDKGRIERLLDGrgSVCEYLLKNVDIPITIFK-- +>tr|A0A1M5M3K1|A0A1M5M3K1_9FLAO Universal stress protein family protein OS=Salegentibacter echinorum GN=SAMN05444483_1243 PE=4 SV=1 +-MEKKVLVPTNFSKHAWNALVYGLNLYRDIPCTFFILNTYEASNRLsfpktkkGESEDAKLesekglqkilqGLNfrKeNLQHKFEVISSKKDLTKAIQETVDQHNIDLVLMAAHGAKVSINTAFENEISEVTDVIQnCSFLILPE- +>tr|W8T8A6|W8T8A6_EUBAC Uncharacterized protein OS=Peptoclostridium acidaminophilum DSM 3953 GN=EAL2_c18130 PE=4 SV=1 +-MIQSILLPVEGIEFSKRAYKIALDIAQKYGAFVTILHIDKRPAYapvepvkakpPkkgnvsEfkhaarskgkndIANSAKAYFGAHGI-KVQVIVTYSDTVQAILEHAASGKYDVVIMCNYEDSLIKKFATSFTIKRIIAKSQIPVLVVQA- +>tr|Q7MSX9|Q7MSX9_WOLSU Uncharacterized protein OS=Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) GN=WS0007 P +SSKFPLLVATDLSPTGKVVLEKAFKLAKRYHKPLFILHVSETTLFAPkiieltQIEANLCKlLEPFyaRypEVKATLLCRQGGIEESIISAIKETQASLLLIGTSGEDnLLREFFLGSHCRKIIRSSTIPVLVVKN- +>tr|W6EUE6|W6EUE6_SULMU USP-like domain-containing protein OS=Sulfurospirillum multivorans DSM 12446 GN=SMUL_2828 PE=4 SV=1 +MEKLTMLVATDFAESSAAVLKKAIDFAQKTQATLHVVHVVENTFFQKnqnidfIKEHCWDSMLSHyPsLHKEHFYCFEGNVETVVAIVAQTIGAKIVLIGDNRDKhPLEAIFISSDTKAIIRESHTPVLVAKN- +>tr|A0A193LDE9|A0A193LDE9_9GAMM Uncharacterized protein OS=Woeseia oceani GN=BA177_04385 PE=4 SV=1 +-DQGCILAAIGMPDRgplltelDSYILAKAAAIALAEFRELHVVHAWQLSHEghmRsfgtKaanlevdrMIAReaalrtnglrrAIEATTSEsAriatdFLAPHLHIIKGHTENVVPELADRLGAGLIVMGTAARTGLSGLWIGNTAEKVLSRSDRSFLIVKAP +>tr|A0A0S4I322|A0A0S4I322_9PSED Universal stress protein E OS=Pseudomonas sp. URMO17WK12:I11 GN=uspE_5 PE=4 SV=1 +--PRKIVAAVDPFHRngqyksfNDRILQEAQKLASTCHAELDVIYAHDLSSISadefgfangstffssSKAKmlfdaqaDAFRElSERNGIPPERQHLIMGNPVKVLASYAAAYETDVIVMGRIGHRTMDR-FIGSTVEQLLFKMPCSIWVI--- +>tr|A0A1C7ZAP5|A0A1C7ZAP5_PSESX Universal stress protein OS=Pseudomonas syringae GN=AFK24_06080 PE=4 SV=1 +--PRRILAAVDPFHRdgryqdfNDRILHEAVKLATACDARVDVLYAHDLSSISsaefgfddgsaffssKVAKtlfeaqgEAFNElADRNSIPPEQRHMIMGAPANVLSAYASAHDIDVVVMGRVGHRKPGR-LVGSTVESLLYKVPCSIWVI--- +>tr|A0A1J5DLV9|A0A1J5DLV9_9DELT Iron/manganese transporter OS=Deltaproteobacteria bacterium CG2_30_66_27 GN=AUK27_01645 PE=4 SV=1 +-PFRKIAAALDFGEADAEVLSRAAGLATANRCPLLLVHCVESAGAaamggeitdteskkdLERLQRYTLVLGKHDI-QAEAELGFGDPVRVLPEIVRRHGVELIVVGAHGHKGLSDWLHGSTIDELRHRLNISVLVAGR- +>tr|K8EZM2|K8EZM2_9CHLO Uncharacterized protein OS=Bathycoccus prasinos GN=Bathy02g01870 PE=4 SV=1 +-SRRRRVLlPVDITSSSEEMCAWACENFFRPSDIVTVLSVAKKQIVPhgssyfglshdhseaEAVLHAQEWIethikprlEKCGC-GVEVIvklleTDKHHVAEAIIEESKRvdenensrYKFEAIVLASHKRGAIKEFFLGSVANYVLHHANIAVVVQRM- +>tr|I0Z066|I0Z066_COCSC Uncharacterized protein OS=Coccomyxa subellipsoidea (strain C-169) GN=COCSUDRAFT_62559 PE=4 SV=1 +-------MgtPGDCTHDAEDAADWAAVNLFKPGDEFHLVHVIKDESEQlrefyqekSLEVAANRFIqerfvpklVAAGI-IVVVDivrkpSDEAHPASAIVKKADEIDAACIVCVPHEHEFVEAAFHTSIAKWIVLNSKRAVTVLHP- +>tr|A3ZQS7|A3ZQS7_9PLAN Uncharacterized protein OS=Blastopirellula marina DSM 3645 GN=DSM3645_20637 PE=4 SV=1 +--QDVVVITYDGSIPSSHALHMWTLLKLRRpETQVHVVSVDRDLAIaQKHCEEAAVLLQYHQVQATlHPVQLTSKVVTHLSETIAEIAPRTVVMGAYGSGGFREALFGSSTNRMLENSESLLFLY--- +>tr|A0A1G0CM58|A0A1G0CM58_9FLAO Uncharacterized protein OS=Fluviicola sp. RIFCSPHIGHO2_12_FULL_43_24 GN=A3E30_02200 PE=3 SV=1 +--HNLYIVPHDLTPVGDTALEYALFLGNHVRTEVMVLNLVDNKAKiAPTQQKLEAIVASKqipASVNVTVNVALGDIFTDISKIANKEHAQLIIMGTHGAKGFQ-KLTGSYAMKVITSCDVPFMIVQD- +>tr|A0A183R8G3|A0A183R8G3_9TREM Uncharacterized protein OS=Schistosoma rodhaini PE=4 SV=1 +--LRKVLIPLDNSNESKKALNWYKENMKRDGDLVIFVHVIDPILPsalsalshecesmpagssfhvpEESMKSAKILCQemvneatKYGIKS-EAVIqIDNKAGPALVKTINERKINVVVMSKRGLGFWKLNFTPSWHILSD--SRLNSRMHQP- +>tr|A0A0R3SUQ1|A0A0R3SUQ1_HYMDI Uncharacterized protein OS=Hymenolepis diminuta PE=4 SV=1 +--DRVFLFPVDDKRTTQRAFLWFINTFVQSRDEVVVLHVIKPIDDvveelgysvfssypaptrglvmDNRVAEARKICStylefahSRGLTGIRGSIsTHEKVEEAIVKSAMVNKATTIVMPTRGLGRWRLFWGNSVSGFVSKHSTIPLIIIPP- +>tr|A0A202DW36|A0A202DW36_9BACT Uncharacterized protein OS=bacterium J17 GN=BVY02_01060 PE=4 SV=1 +---SSLVIGYDGSAASERVIRLAANIAEAMDLgTVHLLTIDSDLErAEKVQAPGLDYLSAYDF-DLVPVCLDGEAAEEIISYAKEVDASIVALGAFGTNRFIEKVFGSTTQTVLDGAPSAVLLVS-- +>tr|A0A0J1FNY3|A0A0J1FNY3_9FIRM Universal stress protein family protein OS=Desulfosporosinus acididurans GN=DEAC_c27610 PE=3 SV=1 +--NFNVLLYSDGSRQSISAAVYAASLINNiPNMKLTILQIHESHERfmgsefswielrrkykriyweseselswsqtylkipdDDWFKrmlnseedcgdqyarivsKTNRIFVESSH-SIKHQILysninksdISDTADLILNYSSRNSFNLIIIGLQGFSMFNGLIFGGLAHKVQNKSSIPVLLIK-- +>tr|F2ICK3|F2ICK3_FLUTR UspA domain-containing protein OS=Fluviicola taffensis (strain DSM 16823 / NCIMB 13979 / RW262) GN=Fluta_3502 PE=3 SV=1 +--RNLYIVPHDLTEVGNTALDYALFLGRHVRTDIMLLNLVDNKAKIaGVEAKLWDIIkakVIPESVEMFVLVAVGDIFTDISKIANREHAQLILMGTHGAKGFQK-LTGSFAMKVITSCDVPFIIVQK- +>tr|A0A1Q9GFD6|A0A1Q9GFD6_9GAMM Universal stress protein UspA OS=Photobacterium sp. 13-12 GN=BIT28_25240 PE=4 SV=1 +-MFSKIMVPVDLRHEeqLTKSLDVVAKLAKVYGSKVVFVGVSLAAPTeisrnpeeyKAKLALfTQEQSDLHNIDaESHP-IFSVDptadLNKKLLDAIDEIGADLILMATHIPN-VSDYIFANHGNYISDHADISVFLVRG- +>tr|A0A0U2XLX3|A0A0U2XLX3_9BURK Uncharacterized protein OS=Pandoraea norimbergensis GN=AT302_16845 PE=4 SV=1 +--PLDILVPVSGTDYSRHAAELAITLARATNAPVTALHVSARMApgmmhkrwrprSLRpdaaeaaMLENLQALAERNGV-TLRTRLLAGgKVDEAVLHQIHHGKHNLLVLGVQPRF-GDRLNFGAISHRLLEERRCSVIVLSA- +>tr|A0A0J1GWN9|A0A0J1GWN9_9GAMM Universal stress protein family 1 OS=Photobacterium aquae GN=ABT56_16125 PE=4 SV=1 +-PVKQVVAAIDLANQdyqefNAKIVDLAVEFCSVTGAELTLVHAWRLESegFlrkwsgYEdldiallsqqMRSERLERLKSllipYenSPIVKHIKLLEGETREVLPRYVATSDTDLVILGSLSRTGIAGFLMGNTAESMLNTMSCSVITLKPD +>tr|A0A177QC71|A0A177QC71_9BACT Uncharacterized protein OS=Nitrospira sp. SCGC AG-212-E16 GN=AYO43_08365 PE=3 SV=1 +-SFRKIFHPTDFSAGDAAAFAHAVKLACLVQGELTMMHVDPAIERkdFEDFPRIRPLlvrwgvlqegcskddVAKLGVQIKRVRAVADNTTGALLQQLTAHPTELLVLSTHQREGLARLTHHAVAEPLARGTHARTLFVPAG +>tr|M5SZ63|M5SZ63_9PLAN Universal stress protein OS=Rhodopirellula sp. SWK7 GN=RRSWK_05272 PE=3 SV=1 +-LARFILHPTDFSTESSVALAHAVHIAVNNKATLELLHVETDPaaneddqddvPDedWNQFPSIRTMletwglipsgdarsdVTDLGIEISEVVSYGADVPEVIAEYCQRRPIDMVVLSTSGRDGFASLLMPSTAERVANKMSnllIPTLFVPKH +>tr|A0A1Y1QIR7|A0A1Y1QIR7_9GAMM Uncharacterized protein OS=Thiothrix lacustris GN=BWK73_31120 PE=3 SV=1 +-QFRTLFHPTDLSAASEVAFVHALKLAVMNKSSLTLLHVAGKHAHvhSNHFPSVRETlegwgeipphsdkaaVFALGVTIHKVVSKPEDPVRACQRYLESHSIDLVILAVHQHNSRMGWLHASIGQPIVRNSGETALMLPHG +>tr|A0A133VL21|A0A133VL21_9EURY Uncharacterized protein OS=candidate divison MSBL1 archaeon SCGC-AAA382A20 GN=AKJ51_01975 PE=4 SV=1 +-MLEKVLAPIDSIKwdNTKTAVESVMKIGRSYRvngsPELNFLHVFHAKPKIPMaerdritdLkkreikedfETIKEMCKENGLENVRTVTRTGKPAKEIVKYAEEKNVDVIVMGSGKlhdrttTGKIHKFFYGSVTERVIHEAPCSILVAKPG +>tr|V4C3I4|V4C3I4_LOTGI Uncharacterized protein OS=Lottia gigantea GN=LOTGIDRAFT_231833 PE=4 SV=1 +-KTSTVLLAVDNSSNAEYCMNFYLQRLHKQGNKLVILHVPEYWGDmarmmsparlTEVYNesqkrakVIGEKFHtiaaKNSVSDIEFvTKDGNDPWHVIVDVAKDKKVDFIVMGSRGMDFLTRASIGSVQANQIAPFEVGCLFQ--- +>tr|M5RSV9|M5RSV9_9PLAN Universal stress protein OS=Rhodopirellula maiorica SM1 GN=RMSM_00711 PE=3 SV=1 +-DPMKITIGYNDCEGSAEAICEFTKLDWDTTAAISLLGVVPVFQGFspdlmpnivqyrseqrvAAmryLQSGRERLVSehsqLSTDQISCDvVDTDHVGNAIIERLEEEKSDLIVIGDSHRSRISRMILGSVSRFVLHHAHCSMWIARD- +>tr|I2K7U4|I2K7U4_9PROT UspA domain-containing protein OS=Sulfurovum sp. AR GN=SULAR_03582 PE=3 SV=1 +-ELKRILVGLDVTEKSNNVLKRALSVANEHKADLFIVHAVQTPWLGVPsyfggkdvvidhqsiAQKIEKKikpLNREFKVNCFVFVKEGNPQDVILYESKLNQIDMIIIGAHSKAKGKKGFLGTTAQKVAHLSHLPVLIVKN- +>tr|G0HR54|G0HR54_HALHT Universal stress protein OS=Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 / VKM B-17 +----TILVAIANDSVSPAVIDTAVRLADGLDEELYVVHLVDEDTadgtAMQLRDEMRERFRDATIVatvAIEhvgrSAMRSGTrIGNELLELAADVDVRHIVMGHEPKGLAGRLREGDAAVAVIDAADVPVTIVPE- +>tr|A0A0S8KP93|A0A0S8KP93_9BACE Uncharacterized protein OS=Bacteroides sp. SM1_62 GN=AMS23_06320 PE=3 SV=1 +-KNRQILVPLDLSKAIQSKISKAIEFAGILHSDVSVLTILRSDGSnleaqyRRRLDEIREIFNNAGV-TCKVKLVKSkhPVPQEILSF-AkSTRVDLILIMTQQETHYTDRFVGSAAQEIINQSEFPVLSIRP- +>tr|A0A0R2VHU5|A0A0R2VHU5_9SPHI Uncharacterized protein OS=Sphingobacteriales bacterium BACL12 MAG-120813-bin55 GN=ABR95_11340 PE=3 SV=1 +-QFKNLLLPIDLSRHTNEKVERILRFAQEFHCHIHLLAVSEFLeeLTfskkelLERLEASAQYFKAAGL-RCSTEIIRHdLVSHSVVAYATEIKADALVVMAEHKSIITSMLLGDRTNKVVATSPIPVISFRP- +>tr|A0A0S2I4Z2|A0A0S2I4Z2_9BACT Universal stress protein F OS=Salinivirga cyanobacteriivorans GN=L21SP5_03721 PE=3 SV=1 +-NLDKIILPLDLTKETREKVTDAVHLAKRFHSKIYAVSFSSTRDDgvvghlKGQLRQVSDFVEKAGI-EIETDFRFYdgNRRKKFLEYVQDKDADLVIITTHQQPEIVRFFMGSFAKEVVHSAPVPVLSIVP- +>tr|K0NDJ0|K0NDJ0_DESTT Uncharacterized response regulator receiver domain protein combined with universal stress protein domain OS=Desulfobacula toluo +---MKILVGYNGGEVGRLALSLARDYALKNNAFVYIITSMQGGTSEKqsDILKAEenlefaKKLMEhSKVkYDAQQSVRGLSPGEDLVKFAQENDIDHIFLGIKKTSRTQKAFLGSTSRHVILKAPCPVTTVKF- +>tr|Q0AC76|Q0AC76_ALKEH UspA domain protein OS=Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1) GN=Mlg_0206 PE=3 SV=1 +--VALVILPVDGSPACVAAAGHAGLLAQVLHARLQLVHVMPPIPAEfsdlpanrkpetdqdraEQLENArqafekaRAILDPSLEPEClTLEPddesLVHRPGRVVADHVRRQSDCLLVLGARHMSDLVKLVEGSVSNEILHRVQCPVTVVHD- +>tr|A0A179EJU5|A0A179EJU5_9EURY UspA domain-containing protein OS=Haloterrigena sp. H13 GN=HTG_09925 PE=4 SV=1 +-DPAHVLVPTLGRPREDEALAYACETF--PDAEITLLAVVTPLDAplseggvlerdDERTAAARESatelLASVddptATERVRIETAEGRPGTVVPRYASDEGVDHVVLCGSg-SgsVGFFRRFLGrGIAATVVERTAEPVTVLE-- +>tr|K9YJJ2|K9YJJ2_CYASC UspA domain-containing protein OS=Cyanobacterium stanieri (strain ATCC 29140 / PCC 7202) GN=Cyast_0598 PE=4 SV=1 +-MLQRCLICTDLKDGLHKLTRFVASFEHSGLKEITFLHSVPVWTegeipriDYERIEEVKNFLSSQlenvpDTIKVNIEVISGDATPNIIETVEKYNIDFVILGTAVRTAIQEGLFGSTATKLTKKLKVPLMILRP- +>tr|A0A152A6F1|A0A152A6F1_9MYCE Uncharacterized protein OS=Dictyostelium lacteum GN=DLAC_01821 PE=4 SV=1 +--MVNFMIAVE-SSDIEHTLNEVVSHIFnKQNDHLFFITIVEDItnfpssPMStvfiaDSMKiierKHKDilieccnKAQGLGLSNIKALLGHGSnAGDHICKAAKEKQIDYLVVGRRSMGSIKRIFMGSTSKYILEHAPCNVICIKD- +>tr|Q556D4|Q556D4_DICDI Uncharacterized protein OS=Dictyostelium discoideum GN=DDB0203317 PE=4 SV=1 +--MVNYMIAVDEGSNTEHSIKEIINHVFqKDKDLLYLISVAEDPitfpssAISavvvsETLKaierKHKSilinranLCKNLGVQNVKALLGHGNhVGEAVIKAAVEKDIHYLVVGRRGIGPIKRIFIGSTSRYILEHAKCNVICIKD- +>tr|A0A0H3ADA2|A0A0H3ADA2_DESVV Uncharacterized protein OS=Desulfovibrio vulgaris subsp. vulgaris (strain DP4) GN=Dvul_2842 PE=4 SV=1 +--MRRILLGSDGSVEARHAEDHVIATLRREGGSVMALHVVDTDLMhyglvdqlatqsdketfLnyvreqgeseceARLGGFVERARKSGV-HALLGVRWGEPLREVLAAATENGADEIVLPPHSW--GMDFTTPHLAERLNRSSPCKITIM--- +>tr|A0A1F9KDG4|A0A1F9KDG4_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFCSPLOWO2_12_FULL_60_19 GN=A3F90_01050 PE=4 SV=1 +-NIRRVVFASDFSPESRKAFRRFCETFAPMNAEIFLYHAVPRPPKwtiqsgTNLFvgdatksrqeklsmrkKLARPFLeeaTAAKA-RVEISVeeVEGKIHEAIVRKAVKERASVIGMASRT-GTVAATLLGSATRGVVRHSPVSVWVFRA- +>tr|A0A0D6AGR5|A0A0D6AGR5_9CHRO Na+/H+-exchanging protein OS=Geminocystis sp. NIES-3708 GN=GM3708_2417 PE=4 SV=1 +---LRLLAAIDNSPLTNTVLLKVAELARRSNAEVIVLHVVEQDDPQilQYLEaQTQTLLAD--I-RYRFITTVGVIPEEIVKVADYYKVVELIIGKRGHNHWENVLISSKSQTVLETSAIPVILV--- +>tr|A0A1H4KZJ3|A0A1H4KZJ3_9BACT Nucleotide-binding universal stress protein, UspA family OS=Terriglobus roseus GN=SAMN05443244_1417 PE=3 SV=1 +-KPQAVVLGTDLTATSGVVAGTAIEIARRLDVELCILHVFQYLIhhryrmpvsWmlEEVrrdinakLRRLKKRAEDSQCSASTKVIESEDPAGSLLKESARFERAILVLGTHARDPIERFFLGSVAEQVLRTTRFPVITVGP- +>tr|A0A0R1L5R6|A0A0R1L5R6_9LACO UspA family nucleotide-binding protein OS=Lactobacillus koreensis JCM 16448 GN=FC99_GL001273 PE=4 SV=1 +-FFRRILITIDEddRPSTSRAFRFALTMARDYQAHLGIASVLESDDIsiYeslmptklnekrdhlrSIVQEYAAKAKAFGVNDVRSIVAEGgDVDDVVLQkIIPDFQPDLVVCGADVDFASHG-HPGAIGLRLAKKSDVSVIVIR-- +>tr|A0A0G9GN94|A0A0G9GN94_LACPN Universal stress protein UspA OS=Lactobacillus plantarum GN=WP50_26545 PE=4 SV=1 +-VYRRILLTVDEddNTSSERAFRYATTLAHDYDVPLGICSVLESEDIniFdsltpskiqakrkhveDVVAEYVQLAEQRGVNQVEPLVYEGgDVDDVILEqVIPEFKPDLLVTGSISIHFNEE-INYGKSKN-ARATCLSANFTD-- +>tr|K1YED0|K1YED0_9ZZZZ Universal stress protein Usp OS=groundwater metagenome GN=ACD_73C00798G0008 PE=4 SV=1 +-PPQKIVVPVTFEEKTFEVLKNLLFQFPEAQTEYHLLHILSEPDLYGVykdilnnpldmnvdlLvKMAQQGLdnlaKKVFQIDITKKILQGDMAEETRNYAQLIGADLIAIPTHHRGGIKHFFLGSEAEKLVREVNNNVLCIS-- +>tr|F1WN98|F1WN98_MORCA Universal stress family protein OS=Moraxella catarrhalis 12P80B1 GN=E9O_03364 PE=4 SV=1 +-MYQHVLLVTDLKDDTDLVAQKAKWiLDLQPQAQLSVLHIVEETMLgfgYelipasalhehiddERCQTARIRLadvlARNHLQAHHINIKTaISGRKGIVDYCQAHAVDLVVIGRHKRTGLSAWIAGATADSILPDIDSDLLVVQL- +>tr|A0A229H3U9|A0A229H3U9_9GAMM Universal stress protein OS=Moraxella sp. VT-16-12 GN=CEW93_00610 PE=4 SV=1 +-MYQHALMVTDLNDDTDLVAQKAKWiLESSPATQLSVLHVVEETMLgfgYelipatalheeiddERCRMARTRLaevlARNNLQAHDAKIKTaISGRKGIIDYCKSHAIDLVIIGRHKRTGLSAWLTGATADSILPDVDADFLVVQL- +>tr|A0A1F3WY99|A0A1F3WY99_9PROT Uncharacterized protein OS=Betaproteobacteria bacterium RBG_16_58_11 GN=A2Z01_10690 PE=4 SV=1 +LTAKTILLAYHGTEGAKRAEALAYEIISREGGRIVHLLIVPeDVWvgmqgddWlnnastrdtyGSYVegvleKDAaeqVAVVeahcKQHGL-AYTPILRLGDPADCVIAAAREEKVDLVVIGPPRSKKESGLRSRMELDTLGRGLPVPYVVACG- +>tr|Q1CX24|Q1CX24_MYXXD Uncharacterized protein OS=Myxococcus xanthus (strain DK 1622) GN=MXAN_6935 PE=4 SV=1 +--VSRLVLGTDFSLRSEFALARALRLPLAHGSVFCVLHVAPVLDGQegpggtlsgaRCLRKAvssvCRRLRNRVDIDVREELGRGDPVEVASAVARMSGAELVVLGRPHvTYPVRALAEDSTVRRMVRHLGVSVLVVVPH +>tr|W7BXN1|W7BXN1_9LIST Universal stress family protein OS=Listeria grandensis FSL F6-0971 GN=PGRAN_00015 PE=3 SV=1 +----KIGVLIADDQLSKKIMEKTIGLCREFavPPEITLIHVVNMKGIAedievgvdleGdLITDAQKMlaekgtvLEAARF-GYKTAILNGFPAKEVTKYANDGKLDMIIMGHHDLSLMQKVTIGSVAKKIIEDATFPVLLI--- +>tr|A0A1J4SWM4|A0A1J4SWM4_9BACT Uncharacterized protein OS=Elusimicrobia bacterium CG1_02_56_21 GN=AUJ51_05065 PE=3 SV=1 +-KIKRILVPLSGSLVSDVSFYAALKIASKFGSKIIPAHVAKDGAAAglrgaAFLNQVCAQWSSDAY-SLEPLLVHGEVKKELVSLCEKGNFDLICLSSTKFNPLAKLSGDSFSFNIIYATTPPIILMRP- +>tr|L0FWR3|L0FWR3_ECHVK Universal stress protein UspA-like protein OS=Echinicola vietnamensis (strain DSM 17526 / LMG 23754 / KMM 6221) GN=Echvi_0795 P +-TFAKITLALDFSSYTEKLLQLGTSLSKKVHSEILPVHVIKLGvqyfPYIknykKiseeLEKEALKDFKklqKrFHLhAPLTIVKDNEQHiSRLIYQNAVLNASNLIIVGNKGKKNEGDLLIGSVAEQLIAYDkNLPVWIVK-- +>tr|A6GC05|A6GC05_9DELT Uncharacterized protein OS=Plesiocystis pacifica SIR-1 GN=PPSIR1_24204 PE=4 SV=1 +---GPIVCAVTPEPASLAAARYAMQLGKAIDRPVVYIQAIALSVPMglpyvpeSAWVdlheqhmgRSQEtlaqWCDKNGLEG-EQKVISGPVVYELIATARRLDGCMIVCGSRQLSTAERLWTASTGMGLAAGSHLPVAIVPPE +>tr|A0A1F7MKP7|A0A1F7MKP7_9BACT Uncharacterized protein OS=Candidatus Rokubacteria bacterium RBG_16_73_20 GN=A2W08_01830 PE=4 SV=1 +---GAVTALSALTDDSTEACRFAAAFAERAARPLALAHVANDPRLDaaahiprSTLDrmaadfaaAGRAelphWLEVNDLRPMVAIVLQGDLVSSALAFADVQRAPFVVVGAHAPTGLDRVFAPRVGRELAAVSRVPVAIVPPV +>tr|A0A1G8Y0D6|A0A1G8Y0D6_9EURY Nucleotide-binding universal stress protein, UspA family OS=Methanoculleus thermophilus GN=SAMN04488571_102148 PE=4 SV=1 +---MKILVLIDGSKWSQKAALHAIKLAKRKNAEVVLFSVLDIAEAKamafnfctqsgicemlkdyegRIWNDmkksiaddqnnILTRYRGEKI-LCSGKIVEGNIRDEVIKEANSGGYGLVVMGAFGRSGKNR--ISALLEQIGGAVKPPLLVVR-- +>tr|A0A0F7HNB1|A0A0F7HNB1_9STAP Universal stress protein OS=Salinicoccus halodurans GN=AAT16_10625 PE=3 SV=1 +-MYKNILLPYDFGNSFTNVPDELVKLTGQnEDAVITIFNVISETDQADnvkyhgkhfedIckdkvedLKPFTDQLNERGL-KYRTSFKTGRIIPELMNEVHENDYEIVVMSNKRSKRDIKHVLGHVTHKLAKRVNIPVLIIK-- +>tr|C0QFQ3|C0QFQ3_DESAH UspA13 OS=Desulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2) GN=uspA13 PE=3 SV=1 +--HKNVLIAFDGTREVVEAVRRMSRLISNRGYQLLLCHASKNSAdMdk-plslkndQFFKQSVECLTSAGFTegQLTCELIssEGDLTENIVNRAREGGYESILVGRRNLTFLKQFFHGRVGDKIFQAAGnQVVWVV--- +>tr|B2A6S3|B2A6S3_NATTJ UspA domain protein OS=Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF) GN=Nther_0609 PE=3 SV=1 +-MFKKALMPLTLREQQDEFLSSVSLLAKLSTNTVHLCHVIDSGFTkyslvSNKIKLYKNILADKfpSL-NVSSEILSGHAGSKIIESAKTSESEFIYLPASQRHRLGQLLIGSTASDVVRLSDRPVFVHK-- +>tr|H1Z0P2|H1Z0P2_9EURY UspA domain-containing protein OS=Methanoplanus limicola DSM 2279 GN=Metlim_1188 PE=4 SV=1 +-MFERTLIPVAKGEKTEEIIKITDTLANLGMNSAVLFNVHEPESIfsknsYSWFDNMMEELEGAGL-PVEAKTGTGHTASAIAEAAMFENADAVYMKTRRKWHIETMLLGSVSRDLLRMTEIPTFVHK-- +>tr|A0A1Q2HRU1|A0A1Q2HRU1_9BACT Universal stress protein F OS=Phycisphaerae bacterium L21-RPul-D3 GN=L21SP3_02006 PE=4 SV=1 +-MFNTAVIKLDLKEPAEKLLEMAEFMQHFGTKTLHIISTADNHG-nrksiNAKTEEAAEKFRSLGY-SCQVHIRRGNPATQTLKLAEEIKADYIGLYWIPASVIRRALLGSVDAEILWRSSMPVFVYK-- +>tr|A0A226BUS2|A0A226BUS2_9FIRM Uncharacterized protein OS=Natranaerobius trueperi GN=CDO51_12285 PE=4 SV=1 +-MLQKALLPITLQESKTDILFYVTLISKLGTKRVHMCHVVDSGFAnykqlSNRIQVFEQWINENffNL-EITSEITSGHTASKLLSSAKNSRVNYIYLPASKRHRLGKILLGSTAADIVRLTDLPVFVHK-- +>tr|A0A0Q6PJ06|A0A0Q6PJ06_9MICO Uncharacterized protein OS=Microbacterium sp. Root322 GN=ASC55_02280 PE=4 SV=1 +-MPARYVLALKGRGGEETAHAWAESHAAAAGVPVVRVHVATGD-DAD-F------AHPEPHRTTDVILPRGPVPEHLARFLQ--DDDALVISTGKTGFIHSRVFGTMSLRIAAVARCAVVVVPH- +>tr|A0A1H4IRX6|A0A1H4IRX6_9MICO Universal stress protein family protein OS=Microbacterium hydrocarbonoxydans GN=SAMN04489807_0214 PE=4 SV=1 +-SRSRRIVGIDGTATAETALRWAARRSTDDGAPLLLAHVGPFLGQS---DASvledarAIIGAEHAGLAVESRDLRSPVWKALSEIAD--PDDVIVIGADTAGLGRSRVSGALSVQLAIRSQCAVAVIPD- +>tr|M3PVV8|M3PVV8_HELPX Universal stress family protein OS=Helicobacter pylori GAM96Ai GN=HMPREF1430_00225 PE=4 SV=1 +--LMNILFGISDTQECYNAIKFAVKLAHSlKEVRFTLLHVSMEVFIYsesgmmdyGqtealeeekakaLLKQFEDAFKKENI-ECESVLKSGDLIDVVLDMAK--DYDLLLIGASESNLL-YRLFISHQNSLVEQSSIPVVIAK-- +>tr|A0A0Q4B780|A0A0Q4B780_9BACE Uncharacterized protein OS=Candidatus Bacteroides periocalifornicus GN=AL399_04980 PE=4 SV=1 +-DIRTILFPLDTTFESRQKTPYVARLAKDWNADVKILAVMESANKavraklQSYLAQVESYLDDRKVRHAAQTVQDADLVDLTLEQAASTPNSLIAITTRDKEAPRIFLVGNKPQRLISQSPVPVVAVAP- +>tr|A0A132I2L9|A0A132I2L9_9BACT UspA domain-containing protein OS=bacterium F083 GN=F083_350 PE=3 SV=1 +-SLEHIVVPIRVSTSSREKIRPASMMARIFGSHVHILGLQDIPAEeqtlHAYMKQSADYLEAEHIPHTMTVRKSTNACDTILSYAYEINADLLVIHTEQDKFVKQLFLGTNAQQIVHKSQIPVLSLHP- +>tr|A0A1F5IWH4|A0A1F5IWH4_9BACT Uncharacterized protein OS=Candidatus Dadabacteria bacterium RIFCSPHIGHO2_12_FULL_53_21 GN=A3J42_03200 PE=3 SV=1 +-GFKRIIVPVDLSHGLGKSFDYAVDLAAAFGSTVHVANVVETGYQkypselAEQLRgFAHRELKEtvgsTRLkDDLIINtVIAPNGWRGIVDFAFEKKADLIVIMTYGGGRFKKEFIGSVAEKVIQEAHCPVITMTP- +>tr|A0A1F6VHY9|A0A1F6VHY9_9PROT Uncharacterized protein OS=Candidatus Muproteobacteria bacterium RBG_16_60_9 GN=A2W18_07160 PE=3 SV=1 +-TMVRVLIPVDGSRNAQQAVRHVVKDYMKNnELEIHLLNVQPPFSRHvasfvrkrdrdayhreqaeQALSDARALLAQYQV-PFHTHVAIGERAPIITDTARRLNCHHIVIGTARKNSLTRMLQDSVTNRVLELTTVPVEVVAGD +>tr|A0A0H0XLP7|A0A0H0XLP7_9SPHN Uncharacterized protein OS=Erythrobacter marinus GN=AAV99_12700 PE=3 SV=1 +-NEPRLLACIDDLDGVHSLAPHALAVACSLGLKVTFARVIELRRHfsspadpitWHsRQCAERENLRKlvsgQSrepaeggalpaprsgtDQAIDSVLLAGNPGEELADWAKAHDTSVIAMHRRD--SHNGPGLGATAQALMNDGNSSLLLVPPK +>tr|A0A0F7KUE2|A0A0F7KUE2_9SPHN Putative universal stress protein OS=Altererythrobacter atlanticus GN=WYH_02931 PE=3 SV=1 +-SGASILACVDDAPASAAVVLHAFAVGRGLELPITLARVVETSPQiglpadpveWRhRRNEYRSQLRRiaalPPgaSSPAGSILLTGAPADRLSDWAIEHRVPLLALATHGHSSARQNGLGPTAQRILQRAATSLLLVPPG +>tr|A0A074N683|A0A074N683_9SPHN Uncharacterized protein OS=Erythrobacter litoralis GN=EH32_12085 PE=3 SV=1 +-DAAAIIACLDLSPHSQRVARLAAFLARETDRPLILFHAVSDEQPagglpdpleWHlRRSRARRFLEEmaasIEnfPGEIGIGIKEGQWQAGLAELCAMSGPATAVIGKSSV-GDH----VHLSASLLESGAGSLLVVPAS +>tr|W0A2I3|W0A2I3_9SPHN Uncharacterized protein OS=Sphingomonas sanxanigenens DSM 19645 = NX02 GN=NX02_01915 PE=3 SV=1 +-GGFNIVACVGRGPHADFIVPHALAVGKALGAPVTLLQVLEAQAVrdprpdpieWDmRRHDARKLLGGlamvAGdpSGRADIALAEGRTVDEICRYANGKAECVIILGRGAGEDVDPRRIGSTVHNVAGRAPGSILLVPND +>tr|D9PJA7|D9PJA7_9ZZZZ Universal stress protein OS=sediment metagenome GN=LDC_1616 PE=4 SV=1 +-MYQGILAAVNEFINSELAARYAIALAKSCRAKLFLVFIAEDRIDKDAFrhaESALgrlfMEAQGQGI-EVESITEKGSPLRTISAIVKKEQIDILFAASRREDVSKRFFQRTLARDFMLRLPCSVAMVRV- +>tr|A0A1G1FME7|A0A1G1FME7_9BACT Uncharacterized protein OS=Nitrospirae bacterium GWC2_42_7 GN=A2X59_04115 PE=4 SV=1 +-MYKKILSAVNEHLNSEISARYALELARVTSSRIYLCYIAEKNVSEKAFrqaEETVrrlfLRAEDMGL-KVESIFDTGDPVTKIREIVKTEKIDIVFSATRREDVQKRFYAGTIARRLSLNLPCSVALVRV- +>tr|A0A1G0LBI3|A0A1G0LBI3_9DELT Uncharacterized protein OS=Geobacteraceae bacterium GWB2_52_12 GN=A2X80_04820 PE=4 SV=1 +-NYRTIFTVVNEHTVSTVAGHYAIALAAAGPSRLVLYSALQKEASPASIhraERHLeqlfKEASTLAL-PVTRITESGLITRLLPLRADAEHTDLVLYPLTPDEQYHNLLRQQPVHTLLRSIRSDLAIMRI- +>tr|A0A0D8CNF4|A0A0D8CNF4_9GAMM Uncharacterized protein OS=Thalassomonas actiniarum GN=SG35_29030 PE=3 SV=1 +-SADAILLALDFLASStekqqlnKKLLEFARDYADKMAIELHCCFAISPPKVLSdtgfidpeeYAQKStalaketaSVLLEPYQIAQQHQHIKIGSSDKVITGIAQKINAGVIIIGSMGKSAMSGKVIGNTCEQVLHISKKDVLVLGL- +>tr|A0Z498|A0Z498_9GAMM Uncharacterized protein OS=marine gamma proteobacterium HTCC2080 GN=MGP2080_09818 PE=4 SV=1 +-KGSAIMATVDLEATAkakqalnVDVITSARHYAEMLQVDLSVLCVIDVPTLLVdldlidakaYAKERikelqpalTALAKKTGLPLSKFQLKRGPVAKTIVSEAAELKAQLVVMGTVGRRGVRAQVLGNTAEEALQLLKTDTLTLKP- +>tr|Q1NMS2|Q1NMS2_9DELT UspA OS=delta proteobacterium MLMS-1 GN=MldDRAFT_1145 PE=3 SV=1 +TLERKILVALDGSRHSRHTLHYLALLFARrPEVHFHLFSLVGGVNlppggeWLeeserlnmlspqsrqkltthqGYLRQGSEFLASRGVEpgRLssEVKISGDSLAEAIIREARRINCDAMALGRRGMTRVEEMLLGSISNHIFEKCHdIPLWVIDG- +>tr|A0A0M4I965|A0A0M4I965_9BACT Uncharacterized protein OS=Hymenobacter sp. DG25A GN=AM218_15800 PE=4 SV=1 +--MKTILIPLTLTASDEYALAYANKLAVRWRANLVLLYCQPGPALsstdeDallTRMQNHVERMRyqqlvrQDARrLHYHFRALAGSLPEHIAEVVSQNAADLVVMSLEQTHCPAQAMTDNHPVRVSSLVRCPVLVVPPG +>tr|A0A1S8W7D8|A0A1S8W7D8_9FUNG Uncharacterized protein OS=Batrachochytrium salamandrivorans GN=BSLG_00800 PE=4 SV=1 +--SRTLLIATDFSFSSTSVLDWAAQNLTKNGDHIIIIHSIQDVYsgsvVYhddvsycsdidEathisndinfaqvEMESATSFLKEcvygfeksliaSNVtdYSIQKVVSNGPPGPVIVAKAEEYNPDMIVIGTNGRTMLSELIMGSVSSYVSCHFKqCPIIMIQC- +>tr|W7YDM1|W7YDM1_9BACT Universal stress protein UspE OS=Saccharicrinis fermentans DSM 9555 = JCM 21142 GN=JCM21142_31209 PE=3 SV=1 +-GINKIVLPISQRKSSRQKVPAVVGLAKLFDAQIYVVGVKEKGYSLansrvkVFVKQTVKFIEKNTdIKVDSQLITEGKRADVLLKYASTIDADILATGMHHSGNPFENIIKPFVNQLINESDCPVLAVPT- +>tr|A0A1I1YMF1|A0A1I1YMF1_9BACT Nucleotide-binding universal stress protein, UspA family OS=Thermophagus xiamenensis GN=SAMN05444380_10846 PE=4 SV=1 +-NPHKVLLPIDYHKLARKIVPVVAGFAKLLKAEVSVVALQKKSKWLipgrsnIYARQAERYIQNNTsLNVSVTNFNWQGDVKNILSFAREQSASVIAIHLIKSTNPFESFFRPFANEILNTSDIPVLIVPV- +>tr|C0ARF0|C0ARF0_9ENTR Universal stress family protein OS=Proteus penneri ATCC 35198 GN=PROPEN_00370 PE=3 SV=1 +-MANKYLVAIDLLEdSRIQRMIEDiHFLARKPENYFHFITVMPNLRSletyglncdsPSVIEkkqQAlvllTEKLEqcvtqQFNLpkEQYQCHAVIGTPNYNILELAEKIDADTIIIGSSSRNQR-NILLGSTADYIVNNTSRSVMVIR-- +>tr|A0A0P0CYW8|A0A0P0CYW8_9BACT Universal stress protein family protein OS=Rufibacter tibetensis GN=DC20_14375 PE=4 SV=1 +-DIQKVLVPIDFSDTSVHALRLSKNLSDQSNLQLEIMHVYRLPRQfFpliseeKAVkkavEIVKKkfadLQKKHQeIANVPYTLVRaanKSIAERITLHLEKGGHDLLVLGLKGNNPLPSLSLGSVPTEMYNtDIKVPLWLVY-- +>tr|A0A0W8FKL1|A0A0W8FKL1_9ZZZZ Uncharacterized protein OS=hydrocarbon metagenome GN=ASZ90_008795 PE=4 SV=1 +-KFKNILYAIDLDSKNISSLGKALEFAQFLNCSIHILYVNDIGAGYRhptDREDAVAlKVKEvipeSmlENLDIIYAVSKGNTAEEVVKYAQGNDIDLIIVGHKHRGKLYSSVFDSTDVNIVDTAMLPVLVIPE- +>tr|A0A1G3QYV6|A0A1G3QYV6_9SPIR Uncharacterized protein OS=Spirochaetes bacterium RBG_16_49_21 GN=A2W19_10325 PE=4 SV=1 +-NIKNILYPINLDSKNVSLVVKALEIAKEFKSRLHILYVNDPDAGYRhptDREDAVAlRVQEtappEllESTTVTYAVSKGKLDNEVTEYCKNNNIDLIITEHKHKNKLYSMLFDTPDENIIDAINLPVLVIPK- +>tr|W7QWB8|W7QWB8_9FLAO UspA domain-containing protein OS=Cellulophaga geojensis KL-A GN=KLA_10573 PE=3 SV=1 +--MKNILVPIGTSTESHETLQYAVDFAKNFDATIYVMEIFNVKSaGAgslanatDKiEKNSREQLLdvvskvdKKGT-EIKIATYQGDIIEGLKKIDKQfLGIDLIVMAPRSNDINESNYLGNTSGKIIKQTDIPTLIVPK- +>tr|I3C3R7|I3C3R7_9FLAO Universal stress protein UspA-like protein OS=Joostella marina DSM 19592 GN=JoomaDRAFT_1244 PE=3 SV=1 +--MKNILVPIGTSSNTINTLQYAIDFAKFFDSKIYLMQAFTFINKAgsianveDVvAKNTTEQLEevlnkvdKKGV-SVTITAYNGEVLDGIKAVDQQYGIDLLIMEPRSTDIREEVFLGKTTGKIVKQTNIPTLIVPE- +>tr|A0A177NS60|A0A177NS60_9GAMM Sulfate transporter OS=Methylomonas lenta GN=A1359_20595 PE=3 SV=1 +-RIQRIIAPIDFSPVSADSLTQAAAIAAQYKvPEILAIHVYDDESVVRYEehelikrgEEkvrFAEIMgsvDTHGV-RINPLFmESIKAAEEILTEAANYQADLIVISTRGHSKAASILLGSVTSSVMSDAKIPVLAIKH- +>tr|A0A0S8B8W9|A0A0S8B8W9_9CHLR Uncharacterized protein OS=Anaerolineae bacterium SG8_19 GN=AMJ56_12300 PE=3 SV=1 +-KLDRMLLAYDGSPKASEALFVATYFAARWGAALSVLTVETNNTDVNALNRARTYIEQNGVSGANFILKSGPIGDAILETVLSEDIHLLIMGGFGLRSVRRLVLGSTVEQMLQQMRQPILICR-- +>tr|A0A0J1K718|A0A0J1K718_9GAMM Universal stress protein family 1 OS=Photobacterium ganghwense GN=ABT57_06140 PE=4 SV=1 +MSFQHLLLPVSPEQTLGDAYHEALQIADTKSAKVTLVTVIENIDELkeishysctalSLLDKVtkvshqalerhVHCLKVkYPSIKFSVIVRLGIPFVEIIKVANEFKADLIVIDTRCQNKTQACQRGSTIRHLMRKSAIPIWSCAI- +>tr|F9T245|F9T245_9VIBR Universal stress protein family 1 OS=Vibrio tubiashii ATCC 19109 GN=IX91_16790 PE=4 SV=1 +MTFTQLLVPIAPGQEIDDSHHQAFQFANNCSANVTLLLVIKELAEFkeifhlsgsslNVLDQAthhfkdhlaqqARTLSEqYANIRFTTKVRVGTPFIEIIQEADESNSSMIIINSYRESKQDACERGSNTLNLMRKSEVPIWSLSR- +>tr|A6BZN4|A6BZN4_9PLAN Universal stress protein UspA OS=Gimesia maris DSM 8797 GN=PM8797T_21648 PE=3 SV=1 +QSINSILVGVDLthadrlvasdlNEQTAEAVERAIWVARMFNAKLEFFAAIDLSAH-tkHLIQEDkdhlhknvtdeaNAVMqtlieQAkAQGVDSSSKVALGPPWREIILEVIKNNHDMVLVGT-RPHGFTGRLFGGTVMNLFRQCPCPVYAVKV- +>tr|A0A178K215|A0A178K215_9GAMM Universal stress protein OS=Photobacterium jeanii GN=A3K86_19470 PE=3 SV=1 +MNFSHLLIPIVPEQAIKESFEQVFNIADQQASHVTLLAVIEELAEFkeiyrysgttlNILDKAtqvyhdalkqhVQTLKHrYHNIHFHTQIRIGIPSIEIIKQAQASHASMVVIDSHRENKTIACQRGSNTLNLMRKSEVPIWSIST- +>tr|E1TJC1|E1TJC1_BURSG Uncharacterized protein OS=Burkholderia sp. (strain CCGE1003) GN=BC1003_3802 PE=4 SV=1 +TTLSHMLLLYDGTAESQAALSRCKQLSLALKAHVDVVSVVDPDSAnancagmlselayayleelgRRTLSTAVDELIQHGV-TAHGYLSVGCKADAIFRHAVSSPPDIVVIGHRLQRGLARWWRErPVHVDLADRLRGSTIVT--- +>tr|A0A1G3QGC1|A0A1G3QGC1_9SPIR Uncharacterized protein OS=Spirochaetes bacterium RBG_13_51_14 GN=A2176_13250 PE=4 SV=1 +--FSHVIYATDWTAASEKALQLLLHFNKIL-GELEIVNVINRKLTVKDMRELkekmartRKKCLDAEI-DAEAHVYAGNTPVEILTAAKDYKGTIIFVGGRsKKNPIKRILAGSSTCKIAENAPVPVFVIP-- +>tr|A0A0F7PBQ2|A0A0F7PBQ2_9EURY UspA domain-containing protein OS=Halanaeroarchaeum sulfurireducens GN=uspA6 PE=4 SV=1 +---MKVLLGIEGGENSIGVLRRTVERAQRAGDDLTVAILEDEgADqsADAFESDVRSTLAEADC-EADIRRLEENGGSELVRTAERDGFDRIVLGDGKQTPMEKIRLSHLAEYVLLNSPVTVTLVR-- +>tr|A0A126QLZ3|A0A126QLZ3_9DELT Universal stress protein UspA OS=Pseudodesulfovibrio indicus GN=AWY79_07325 PE=3 SV=1 +-MFKDIIVGVTPTGIDACAVKAAIRFAERFESQLYLTHVAGME-qgWGsiehlapsgetdQIGTKIremyAEYLG--ITPGAQVVVVPGIPHSELLRLARQKNTDLIVMGPHTQEYEekrskMWGMAGSTLERVSQRARCPVMIVHK- +>tr|L8HAR3|L8HAR3_ACACA Cyst specific protein CSP 21, putative OS=Acanthamoeba castellanii str. Neff GN=ACA1_327930 PE=4 SV=1 +------IVCVDGSEGADRAMQFALRESPP-DHRLMLLFGAYVPHKEelswgtfsvSSMREghywdkelpdvyikYTDMCQKAGRK-CDfihFHFdRMSKFGDSVCSIADRHHAQNVILARRRQseRSFLGRFLGSGSQAVVDRCGdIPITLVTV- +>tr|A0A1Q7EIB4|A0A1Q7EIB4_9ACTN Uncharacterized protein OS=Actinobacteria bacterium 13_1_40CM_66_12 GN=AUH32_07015 PE=4 SV=1 +-MFSKILVAVGGPDDAEETLSVVSGLAKAFNSEVLVVHMRERVVTSaatieketipeafrfgvkiadQLVQ---AGIKAKAD---IRGHRPDRLAEFILDEAKKFNAELIIIGGHHAHGMRDRIFGDIGKTLAHGSECPLLLM--- +>tr|A0A062UMJ1|A0A062UMJ1_9RHOB Uncharacterized protein OS=Hyphomonas beringensis GN=HY29_00985 PE=4 SV=1 +FAPKNILVLVDMkhKDHADKALNLAGWMAKAMSSNLTLMTVAFPLGKhisdvpekrkPEFLEYVRRQSEKLDVTIEPLFTIHESVVHEVVRVAEKRKIDLIILQSGP-TKMVEHVLGSKASSISLKSKCSVFVVR-- +>tr|A0A1E5SPN0|A0A1E5SPN0_9BACT Uncharacterized protein OS=Fabibacter sp. 4D4 GN=BFP97_05545 PE=3 SV=1 +MAIDRIIIPTDFSTCADRALELALSMATKDLSELIICHINPVAAGgdamffinaeildrtekevDQSFRELLDKFPKLKQVSHKFVQTTGFSVDKIRDVAEEEMADLMIMGTKGRNNRIGEFFGSVASGIMKRSDIPILIVPEN +>tr|A0A1G1FXR3|A0A1G1FXR3_9BACT Uncharacterized protein OS=Nitrospirae bacterium RBG_13_39_12 GN=A2Y97_03440 PE=3 SV=1 +-QWKNIILVTDYSLKDKTVIDEALKLSKIYESNLIIVSGdTGEKNRDEDINIIMKQAEKEGI-AVEALSASGKLPDFIAALAKKRDADIIITGSPVNGGSRYFFKGSLIDQIFDRSICAVLVIKR- +>tr|A0A0F9Z5J2|A0A0F9Z5J2_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0005440 PE=4 SV=1 +----------------HQLTDVAHSLAKLTGGDVRLFHSCYQAPVSGVYPLvvdkalyrekTAGLLAAFSLPEDALCISDEIVTQALPAYLKQQQASVLVMGAVSRSALDRFFVGSTAEKLLDRVDQDVLVVKPA +>tr|W4LK00|W4LK00_9BACT Uncharacterized protein (Fragment) OS=Candidatus Entotheonella sp. TSY1 GN=ETSY1_19485 PE=3 SV=1 +RDIRKPLLATDGSLSAMAALSTAIDFAVQLKLPLSVVHCASPPNRHDAFLDAIERKVASQGIACDVDICQGNAHEDLVRYACERDHDLLLMGAFGHRQIVEWLLGSTTQYLLRTSPIPLVLCHAD +>tr|A0A1F2WKD3|A0A1F2WKD3_9ACTN Uncharacterized protein OS=Actinobacteria bacterium RBG_13_55_18 GN=A2Y75_07730 PE=3 SV=1 +KGKRDVVVPLDGSETSAQALGAAKAISEILGGALHIVHVSEMRIP---KKDLPALLKIEDESKYDIRKLSGEIVPAVLEFALETEARLIVMSSHGTSFKTQDILGSKAKGIAQHTTIPIMIIRAG +>tr|A0A0S8KMW0|A0A0S8KMW0_9CHLR Uncharacterized protein OS=Anaerolineae bacterium SM23_84 GN=AMJ93_05240 PE=3 SV=1 +-TYSRLLCPLDCSQRAEHPLPLASMLARSHRATLILAHVMRRPEMprrrplsdeeraarervvelnRTEARRYLDEMRSAMAaeqVDIQTRLLLSdGPAQTLHHLVREEQIDLVIMSAHGYTGSTSSTYGSLALDFIAYGTTPLLIA--- +>tr|A0A0D5C3Z8|A0A0D5C3Z8_9ARCH Putative Universal stress family protein OS=Candidatus Nitrosopumilus adriaticus GN=NADRNF5_1846 PE=4 SV=1 +NNYKKILVLHGGFEAGDSALAHGINLAKLSNGSVTILHVVNIPKYpmesisnklerielqkklqdtafhmkktmEQEFQKKIKKYNKNKVK-TSLVVLIGPTLQKVLEYEKKNNFNLIVMGKSKGSRSveSRSVVGGLTIKLLEQLRCPTLML--- +>tr|K9H3F2|K9H3F2_9PROT Uncharacterized protein OS=Caenispirillum salinarum AK4 GN=C882_3146 PE=4 SV=1 +RGRRAIVVGLDASPLSVSGLRMAAVVARRWGVRVEAVHVEDAAVARlsshpgvvtvcgltarsrplalapetitaalsaqaRAARDAVEAAKallrrragEGGEAELVFRSRRGGVTRELRAVAD--EaaPSLLVVGWTGQSRARwhrahGIRLGSTARALVQDPSADRVLVVRG +>tr|B4S4N7|B4S4N7_PROA2 UspA domain protein OS=Prosthecochloris aestuarii (strain DSM 271 / SK 413) GN=Paes_1921 PE=3 SV=1 +LSIKRITVALDGSSHSKASLNIATDIARALNAEINGIYVEDVNLLRmaalpfaeeidrlsgrrepvdsaglerslqlqaRQAGQMLRQAAERFRLVHSFRTLRGQVAAQVLAEAL--SSDLLVLGKTGKTPVCRKKMGTTAKAVITSGTTSILLMRPG +>tr|A0A0C1RJ58|A0A0C1RJ58_9BACT Universal stress protein UspA OS=Methylacidiphilum kamchatkense Kam1 GN=A946_09470 PE=4 SV=1 +-MISKILL-FE---NVPFSLRMAALLASKLRAELLGLFIEDVNLLRlsslpfafeteihsaltrslepesllrrfrtmaSQMEQQIAAIAKELNIPWSFQTARGFLWMELIEAAK--NCDLIIVSQKGPFSNFLSFYEDPLFQLLEEAKKPVLFLPSD +>tr|A0A1F3TX13|A0A1F3TX13_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium RIFCSPHIGHO2_01_FULL_40_29 GN=A2622_00285 PE=3 SV=1 +RTIKNILVAVDLSKYSQTVVQQARVLAKKINAPLTFVYAFKDTEMFEspfgvrkaevikYYDQLIRQKYALDE-SIPVVVKFGKPYKQIIAAAKNLKFPLIVAGHRGQSTWTQFFMGSAAEQLGLESPYPVWIHRGE +>tr|A0A098S8Q2|A0A098S8Q2_9BACT Uncharacterized protein OS=Phaeodactylibacter xiamenensis GN=IX84_07375 PE=3 SV=1 +--MRRLLVATDFSPAARTAFEYTLQLAAHLQAEVHLLFINkvvsaetslpeqhrralierDNREYGKKLQRWARHYPDQPReyvaaPNLHFHVRPGKAASGIIQAASELQVEAIVLGGREKHNIREHLFGSVTTQLIGRSPCPMLIIP-- +>tr|A0A1N6IH68|A0A1N6IH68_9BRAD Uncharacterized protein OS=Bradyrhizobium erythrophlei GN=SAMN05443247_03853 PE=4 SV=1 +-KLDHVMVCWDGSRAAARAVADAMPFLTRSG-KASIVVADIQSAKSAdlPGADIATHLTRHGVNVTIERIPVskIDVSNTILSYAADTDPDLSGIPGCGNLFLAGRHVVCLPR---------------- +>tr|R5H3U2|R5H3U2_9SPIR Universal stress protein UspA-like protein OS=Brachyspira sp. CAG:484 GN=BN676_00975 PE=3 SV=1 +---MRVLFCTDGSKISFNALHNFAGWA--RDAVVDVISVIDWTFLPDgicveeegfasscanmadnILDCVQKEIDNSNLTFGQRIKHCGEAVESILEQIKTENYDMVLMGSHGKKGLQSW-LGSVSRDVINNISISSYISKE- +>tr|A3ZQS7|A3ZQS7_9PLAN Uncharacterized protein OS=Blastopirellula marina DSM 3645 GN=DSM3645_20637 PE=4 SV=1 +-MIRSVLLALDASEASQAALQLTIRFCRDhsqredmsnVAIHLTGVAVVDTPNICgpmavplgavtykkdrdevllakanaeaeVILAKFEADCAAAGV-PHTAVRSEGLPYEQIEAVSR--THDLIMIGQDTNFHYEThKTISETVRRLLLDNARPVVVMPKS +>tr|H0I2T1|H0I2T1_9RHIZ Universal stress protein UspA and related nucleotide-binding protein OS=Mesorhizobium alhagi CCNWXJ12-2 GN=MAXJ12_33934 PE=3 SV +-MLRSILVALDGSPSSVEAGLLALELGKRHRAHVEGLGIVNSAWIQrpepvpiggmaykkaldltllktasdrvnAVLRTFGERAKDADFAAFETKRVDGDPRIQIEFQAT--AHDLVVLGRNSLFDVDGelYEMPLHIDKVIRGEPRPVLLVPPG +>tr|A0A1G3HWM9|A0A1G3HWM9_9RHOO Uncharacterized protein OS=Rhodocyclales bacterium RIFCSPLOWO2_02_FULL_63_24 GN=A3H93_14320 PE=4 SV=1 +--GTHPLIAWNNAREAARALNDALPLIENCD-EAMVLSFTARhEEGESCCTEVARHLATHGIKaKTEVmLVQDFGIMDMLLNRVTDRGADLLVMGAHGHIGFPFVSRGAGTRHILRHMTVPVLM---- +>tr|D6SQ42|D6SQ42_9DELT UspA domain protein OS=Desulfonatronospira thiodismutans ASO3-1 GN=Dthio_PD2259 PE=3 SV=1 +--MHRIVFATDFQQAAEKCCQPVFFLGE-LVPELVVLHVgeraADPYSEQLRREHVNAKLEElkeqysGYYRKVRQISRIGSPASHILDVVDEIQADAVILGRLNEPFPLH-VMGSTCARVVSRVNSSVLLIP-- +>tr|A0A1H2UUW6|A0A1H2UUW6_9PROT Nucleotide-binding universal stress protein, UspA family OS=Nitrosomonas communis GN=SAMN05421882_101813 PE=4 SV=1 +---------------MITALLDAVNIASNHNAALCIVHSEDGSDIEVDEKTDITILEKAktylNELNVETRLLDAKkeegingISNAIAAATFEWGADALVVGTTNGRGFEYFYVGSVAEQLIAKVGSLILLVRPK +>tr|A0A135GTS6|A0A135GTS6_9NOCA Universal stress protein OS=Rhodococcus sp. SC4 GN=AXA44_46010 PE=4 SV=1 +---MTVLVAVTDTPEGAHALTVGKEEAERLRTELLVLNLSLTEFA-------PTEIAVAS--GVDVLDRAGrearDPAVAVLDLIQERpDIERLVVLTGQGKKGTVDRTSLLAQVLV--RPARWRR---- +>tr|A7I3R2|A7I3R2_CAMHC Universal stress protein family OS=Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A) GN=CHAB381_163 +SPIKSVLLAFDGTLSSVKIAGFIHNSPLFSNAKKYIINISEDEEKsKEALKIAKDIIGEEN---AKYVYINGTDaGEEIIKFRRANKLDLIATGSFSKNFLKKLIVGSVSQEVITNALVPILVVA-- +>tr|A0A0K1HDR5|A0A0K1HDR5_9PROT Universal stress protein OS=Campylobacter ureolyticus RIGS 9880 GN=CUREO_0067 PE=3 SV=1 +SEIKSALVAFDGGDAAIKTLHSIKDSKIFGQDLeYHVLNINKDEKKsKEILDIARDILKNEN---AKFVSLNGEVADELISYRRANNLDLFVMGSFSKGIFATLFFGSTSKNVVEKALVPVFVAQ-- +>tr|M1E4C9|M1E4C9_9FIRM UspA domain-containing protein OS=Thermodesulfobium narugense DSM 14796 GN=Thena_0371 PE=4 SV=1 +-MSKTILAAIRDVMSDRSVLKMAIDLAKDEGAKLVICHVINRSEDlgvfnpaaeaalvykaERMLEEAIDIAKKNNV-DAIKVVKVGRPSERISELAKQLNASNIVLGNRKLKGIRNWLFSEFSTGFNLKNTTLVSVEK-- +>tr|A0A1N7S2F7|A0A1N7S2F7_9BURK UspA domain protein OS=Paraburkholderia ribeironis GN=BN2475_310075 PE=3 SV=1 +-GIDRILVAVDLSPASLRAAEFVRNIAP-TNAHIRLVSVADNPRSLsslppkasaelyaaraELLRDAADALVQAKHvfsgrdlpleeDLIDLSKRGSDIATALIDAADDWCADLLIVGARQHHGLLRWVEGTVSRPLTIHSRCSLLIVPPS +>tr|A0A0S6VTT2|A0A0S6VTT2_9BACT Uncharacterized protein OS=bacterium UASB14 GN=U14_00353 PE=4 SV=1 +DALKHALLLYNGSPKANEALFVSAYLALHWDWDLEILLTTR---DPLLRSFIAQYVSRRNL-RATILRNtLDEQEDALSTLLSDHQRDIVIAGSSEALPIT------------KTISLPILIC--- +>tr|A0A170PJY1|A0A170PJY1_9CHLR Putative UspA domain protein OS=Candidatus Promineofilum breve GN=CFX0092_b0579 PE=4 SV=1 +ELPRRALLVHDTRRPLDEAIFIAAYLAERWGVALTVLPLSNGRNTHEIAAHISDYLALHEV-AAAFLDPiRPDAraVDRIIATGLGGGYDLLIMTGPARGQRTNYnqQLTAMNGAILQRWPHAALIAT-- +>tr|R6I411|R6I411_9FIRM Universal stress family protein OS=Phascolarctobacterium sp. CAG:207 GN=BN533_02138 PE=3 SV=1 +-MFTRVLLAMDLTPKSEILLPCLYSLCPDTNTEIILAYVFDEEEDadpysssykkvYSKLQGYANELMRNGYEAVSIEMPWGEVFEEITRVGNDKEVDLTLVASHGKGFFRSALLGSTTFDLARSSKRPLFVAKTD +>tr|A0A0S7WZZ9|A0A0S7WZZ9_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium DG_8 GN=AMJ42_06340 PE=4 SV=1 +---KKVMLVLSTTTSSTPFITYSLDYAKKEGAELIVCFIIDEKVSKtvssiltyigfmgekmgenlrktllseyegrakDKLEEVDKLSKKKEV-DCRCILLEGDVVNETIKLAKKEGPEILfIMPPTEKSDVYQTFFGDAINKILRASPCPIKIINGG +>tr|A0A0F9QTN0|A0A0F9QTN0_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0975500 PE=4 SV=1 +---EKFLLSLAARYYNEDLVKYALAFAKQREATLSVLFVLDEELTNgiidqlidvgfigdkpseelrgavlneyeeqakKQLDSIKTIAEKEGV-KISTSVVNGDFVDTTLARAIDNAVDLIILNRERKGAVSKLFKGSPVDKLIKNAPCEVKVFES- +>tr|A0A1K1NCH1|A0A1K1NCH1_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Sinomicrobium oceani GN=SAMN02927921_01137 PE=3 SV=1 +-------------------------MAKLYNSEIHFFHLMKTPVDWvkldkqkekrypetlkeigvvkSKLRELEKKAEHEGLK-CRTFLQFDSGQKDILEHSGHFHHDFIVTGSSGTRGGIRELMGSNVEKIVRKADVPVVVVKDE +>tr|A0A1G1T3E6|A0A1G1T3E6_9BACT Uncharacterized protein OS=Hymenobacter sp. CCM 8643 GN=BEN47_14895 PE=4 SV=1 +-TPLTFIAFADGQASPHHCLRYANTLARAVAGQVVQLRVSEPSvtvpgrlmaepcapddlLCQATTAAELASVAQELRARCVAQVIPDLPPALVRELADRHHPLVFVLSQRYPDDEGDESLATTCAKLLQT-SYPVLVVPLT +>tr|A0A1G1TDB9|A0A1G1TDB9_9BACT Uncharacterized protein OS=Hymenobacter sp. CCM 8648 GN=BEN48_07865 PE=4 SV=1 +-KPLTFVAFAEDTAAPNHCLCYASTLAQSVNGQVLQLRVSGQSmttpgtltaslfepdgqQCQSTAT-DQASEAYKLHEHPAAQLPPDLPPALVQDLAKHHHPLMFVISQGPPDD-EDEEVVDACADLLQT-NYPVLVLPLA +>tr|A0A0C2FBT6|A0A0C2FBT6_9ACTN Universal stress protein UspA OS=Streptomonospora alba GN=LP52_24045 PE=3 SV=1 +SSITRLVVPLDGSREAESAVDPALRIARTLQVPVELLTVHDP-VRGRWARNVDETAAASAYDHVEVTVVgSGWAGDVIVDMIAEQAGTVVCMATHNRDRFSRLVAGSVTEYVLHTAPGPVLMVGPS +>tr|A0A1J0G0P6|A0A1J0G0P6_NOCDA Universal stress protein UspA OS=Nocardiopsis dassonvillei GN=A9R04_09575 PE=4 SV=1 +RSITRFLVPLDGTAGAAAALGPALRAAHVLRVPLELLTVRDR-VNRAWAEDVDAVAAGLDYDRVEVSMVgSGWPGDVIVDAVAEQPGTVVCMATHDRDRFSRLVAGSVTGHVLRQAAAPVLMIGPG +>tr|A0A1X3KLV2|A0A1X3KLV2_ECOLX Putative universal stress protein G OS=Escherichia coli H605 GN=EATG_02895 PE=4 SV=1 +-MYRNIVIPVNVFSRddREQAFCHAQFFANVSSGHVHLLGFIPEYVRilergyvsdmhrleYVLRDQALRRLATlaeqlvLPEGFIHTYVYLGTLPEGVKELAEQQLEDVIVLGATQELG---------FVDMLRQFSVPLLLI--- +>tr|A0A0G4IV06|A0A0G4IV06_PLABS Uncharacterized protein OS=Plasmodiophora brassicae GN=PBRA_007098 PE=4 SV=1 +PHHRRVFVFVspdYDHEPSLLAWEWAQANVIRDGDLVAVVTVVPRPPGStvvpavgmlgaaslafeldalqeqrriqladarKTLARYAESVTPRGWRLETRAIEQadLSIPETIVAWSTKHHADEGVVGTRNLSGFKRTLMalvgkGSVSNQLAQHMPCPIVIVKP- +>tr|J3EVM6|J3EVM6_9EURY Universal stress protein uspa-like protein OS=Halogranum salarium B-1 GN=HSB1_31700 PE=4 SV=1 +--MTTFVLATNSVHTSALLCDYLDDRLQ-AGDTVYAVNSQRGGddtSAaevrdgEDALNAVTARLSGVADVETHQFVRENSPAEDVVGYAEEVDADELVIGVRKRNPTSKVVFGSVAQDILLTANRPMVVVP-- +>tr|A0A161SI63|A0A161SI63_9NEIS Uncharacterized protein OS=Crenobacter luteus GN=AVW16_08365 PE=3 SV=1 +---GFVVLAYDGSTSAARALQQFAFLGVGHERPRKVVAIHPDAAEaGRLADEGAAYLASHGLPaQPVPIASAARPRQLLLAELDSQHASLLVMGTFGHRSWLDRLFGAATETMIARCTCPVLLCH-- +>tr|A0A1W9V7I0|A0A1W9V7I0_9CHLR Uncharacterized protein OS=Anaerolineaceae bacterium 4572_5.1 GN=B6I38_04810 PE=3 SV=1 +-MTKKILIPLTKSASSHKILDEIEKLVPIDNSKLILYYVTKPPKGSGfaapdyrsdyaleaagepvgpkkhpvfssqeedslesdvevALLSVTNKLKAKGYDVSTQVCFVDSVVSEIVRVVKRDKIDMIAMSTRARVGMSRFFFADIAQKVMQKVDIPVLMIHP- +>tr|V8D2L7|V8D2L7_9ACTN Universal stress protein OS=Williamsia sp. D3 GN=W823_07180 PE=4 SV=1 +APAVTVVVGYQPGRGGDEAIELGSGLADALGTSLVLVIATPKPWKTPsmarvdaefaeyaqrygddAEAAARTHLRTRaPGTGVSFRRVSEgSVSKSLHVALDELDADVLVLGTTHGDDGGQMSLGATTSRLMHSSSVPLALAPRG +>tr|Q0A8H2|Q0A8H2_ALKEH UspA domain protein OS=Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1) GN=Mlg_1516 PE=3 SV=1 +RLFRQALVLLDASLSSNEALQAALGLFARGEVALRGLYVEDRDLLRsaalpftrevggysgvcrplasdtlearlrdraQLIRTVLKRVARDYHHHLELEVTRDRVVSAALSLVR--DNDLLVIGRTGWASGQARALGSNARQLVRLAPCSLLIGTW- +>tr|A0A0K0XTD1|A0A0K0XTD1_9GAMM Uncharacterized protein OS=Wenzhouxiangella marina GN=WM2015_533 PE=4 SV=1 +LAGGRIVVLFDGSPGSQAALLQGLAMAQAQQRELVALYLEEAAQIAaaglavagevgavsgqlrplnaeaqaqalrirrRRAQACLDHLMGGPGHSLALDVRQGEAVGVLEALLG--PEDCVVAGRAGFATRHPGRLGRLARRLLSQLLRPTLLAST- +>tr|A0A1M4SIM2|A0A1M4SIM2_9GAMM Uncharacterized protein OS=Halomonas ilicicola DSM 19980 GN=SAMN02745148_00122 PE=4 SV=1 +RLIQRVVVLLDGGRRAQLLLDEVAQLAKREDAELVGLFVEDTELLRaaslpcggeiglisgslrpvapealerrlrqqaDRLQSLLAATAGRHALRWRLEINRDHLEAAALAATM--ADDLLVLYRAGWRHPPEGGFTSrTLSRMLGAAHCRVMMLGE- +>tr|A0A231MZZ0|A0A231MZZ0_9GAMM Uncharacterized protein OS=Zobellella denitrificans GN=CGX12_07370 PE=4 SV=1 +-MIRHIVWYLDLSQAELEMLERVAEFAARHGARLRAVFIEDESLLRsaelpctrevslttgrvreldperirlqlrrrrEHIRQRLQQLARNRALEWSLEVEYGRREQLLARPPAS-RDEVPVLVLD-PATELPTWDRP--------PEHEVLLLSR- +>tr|A0A142VXJ3|A0A142VXJ3_9SPHN Uncharacterized protein OS=Sphingopyxis terrae NBRC 15098 GN=AOA14_07385 PE=3 SV=1 +-MFRSILVIVDPDRraEATRLLEVAAELRRSFDATLTLATVMSEWSvmlraersvgaaglFEAAEARLAALAHSvAAVGDARYRVETGRAHRGILNAAASVNADLILLPSRA-PKWQDRLFGTTAMRVARNSSSSVFIIRD- +>tr|A0A0S8DDG7|A0A0S8DDG7_9BACT Uncharacterized protein OS=Nitrospira bacterium SG8_35_1 GN=AMK70_09315 PE=3 SV=1 +KRFKNILLITNKNDINSSNIIRAVSLARSNKANLTIADVVPGLPlmqrqlipspgiasvLSGLAEKRLNELTFmaqelSAKMDITPLVLQGTPYLEIIRVVMQQRFDLLIKISEPEESFTAKIFDSTDFRLLRKCPCPVWLLKPD +>tr|A0A081N3M5|A0A081N3M5_9GAMM Uncharacterized protein OS=Endozoicomonas montiporae GN=GZ77_21840 PE=3 SV=1 +HAFKTILLAVTRLHSSELELSQTFRLVSDNNARLIIAVFDQSLDvlqrlqflplegklEALCRKQLEEYTEElrakawEEGVQAETCIVPGKPRQVIGGLINEYGVDLVVKLADPCGPLARNQLTGNDLALLRKCPVPVLMMASR +>tr|A0A0S2T976|A0A0S2T976_9GAMM Uncharacterized protein OS=Candidatus Tenderia electrophaga GN=Tel_00190 PE=3 SV=1 +KRFNNILFVSEEPLDhNPAAFERAVALAEQHQARLSVVDVVPESParlqsiadelspamlMDALREERRDALAQlvaahGRGLAIDIQVLSGPHFLAVIRAVLRNGHDLVIKAAHDDTTFKERIFGSQDTHLLRKCPCPVWLLRPP +>tr|A0A1M4XDD2|A0A1M4XDD2_9BACT Nucleotide-binding universal stress protein, UspA family OS=Flavisolibacter ginsengisoli DSM 18119 GN=SAMN02745131_01425 PE=4 S +-SFKTILVPVDFSINTEVAIKKALEVVDRQTGTIHLLHVnhqmksniitvvkrnyqdgyt---LPAEQMLSDWKKCMEDSiPTLKVDISLEHHSSIqMCIEKKTMQLKADLVVIGKKSNHFWLPFLNTVLPNELCEVTGSAVLTVKPG +>tr|A0A1J5TJ63|A0A1J5TJ63_9ZZZZ Universal stress protein family protein OS=mine drainage metagenome GN=GALL_29360 PE=4 SV=1 +MSYNNIVVAVDGSDASQEALDHAVDLARQSNASLTGIFIIDTQWAdfigndwqsakgarqgfldyirkeqEEQAEAAHAQFEQAtqGMEQSCFSVHAGDPTEVLLAQASSDNTGILVAGRRVFQVSGRPSLKSLAATLEKKASRPLILFP-- +>tr|K9GS05|K9GS05_9PROT Universal stress protein UspA OS=Caenispirillum salinarum AK4 GN=C882_1385 PE=4 SV=1 +QGRRAFLVVVDDSPEMTAAARFAARRAARSGGRVALLSVVEPVDGghwmfvgnlmaeearedaERRLQQVAATVHACSGERPELIVREGSLKEQLFKLIEEDdEISILVLGVAANGEGPGPLVQSLTGKNAGKLRIPVTIVPGD +>tr|M4VEP8|M4VEP8_9PROT Universal stress protein UspA-related nucleotide-binding protein OS=Micavibrio aeruginosavorus EPB GN=A11S_886 PE=4 SV=1 +GDGGVYLVVADESEEFNLALRYAARMAQSNRGHVGILHVISLDDVqqwsgvenrmkrelreqsEKFIWSMAKRVNELNGMIPAIYVREGDAKHDvMIDLINEDmTIKMLVLGASASSSGPGPTVAYFTGKGLAKMRVPVVVVPGH +>tr|L8JXP5|L8JXP5_9BACT Uncharacterized protein OS=Fulvivirga imtechensis AK7 GN=C900_01992 PE=4 SV=1 +AMFKRIIFPTDFSESSAKAFSYVLDVVRSHQSELIILYTYRlisgadgryygnkisikrerEEEANKQFEQLKQCYPELSDFEHHFLTEVGFVSDRISLAVERFNIDLVVLSESIQQQLKEKWEM-SDENLPGRFHCPVLLVP-- +>tr|A0A1W9WS53|A0A1W9WS53_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium 4572_89 GN=B6230_04815 PE=4 SV=1 +-MYKKILFGTCLTEYCSNIFNYALNLAQENDAKLWIYYGLGRLNLDEagaeqaikkaeadVAQAYVQQMKDRDFNNYAINVSDGDVVSELSKLARNASIDLMVMGTSTEVPLamggssDVRPLGATIADALLWAPCPVMIIPPS +>tr|A0A199V333|A0A199V333_ANACO Uncharacterized protein OS=Ananas comosus GN=ACMD2_24843 PE=4 SV=1 +-----VVVAVDSREESMKALRWALDNLRlGQPPPEPRAD---PGNCVKNLYHAIKNVT--------------NSRNMWYHLSSSFKMTGKYSSPLVREYRKRMFLGSVSKYCVNHVSCPVLVIKG- +>tr|A0A1V4TSB4|A0A1V4TSB4_9EURY Universal stress protein OS=Methanomassiliicoccales archaeon PtaB.Bin215 GN=A4E30_00615 PE=4 SV=1 +-MLDRVLVTIDLTKASKVMLPFVQQLIDAGARKMTLFHVVQSSKYsmadDARFQEVKQKMEAYQGKldakdcEIDVHLHFGTTTYNILEAAREIDATLIVLGTTGKGYLRGVALGSTSEEVVKGSTRPLLLIPS- +>tr|A0A1M6E548|A0A1M6E548_DESDE Nucleotide-binding universal stress protein, UspA family OS=Desulfovibrio desulfuricans GN=SAMN05660830_01053 PE=3 SV=1 +-SVQNIFLAYDGSAEAGIAARQACALAERYGSRLTAGIAYEMDMEafslspvvesaavektELAVESIKNIVASADVRDFDVAVRYGNPPhEVLVEEAQKSDAGLIVIGACSRSKLSHLLVGGVVHKLVYSSACPVLIVKEQ +>tr|A0A1C6L655|A0A1C6L655_9FIRM Universal stress protein family OS=uncultured Eubacterium sp. GN=SAMEA3545368_03795 PE=3 SV=1 +--MRKLLLPIDGSERSMKAAELVRLLYDKEDVEVILMTVRNDCEFvneESELETIREESLEifsnaekilAGY-HMKKIVDFGHIGNAILRQIEDEKITAVVMTRSTREGYFKH-LGSVTSYVLKYARCLIVIVP-- +>tr|B6AR26|B6AR26_9BACT Probable universal stress protein (UspA) OS=Leptospirillum sp. Group II '5-way CG' GN=CGL2_11238045 PE=3 SV=1 +-PFKSLVLPYDLTPVPPGTMETLKNILHGEGATLHVFHVLDIYEETpmgyplppeysaemekvvcQEVKKLADLYRADGI-ETTSGVYRGRVDRTIIEVALHQKADGILLLSHGKGILGRILLGSASNSVLHHSPLPVILIKPD +>tr|F2NEX9|F2NEX9_DESAR UspA domain-containing protein OS=Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2) GN=Desac_0432 PE=3 SV=1 +RPIQKILVAYRGSQCDQGALQFIAPLFAKQKPEITIMHVQETELGesEEFAQACVltgeDTLREWGY-TPIKKVAKGDFVDEILKAVAVQRYDLLVLGAYGHQRPKYLkIISDEALNLVRLTTRPVLVYRD- +>tr|A0A1X0L114|A0A1X0L114_MYCKA Uncharacterized protein OS=Mycobacterium kansasii GN=B1987_25685 PE=3 SV=1 +--MKPVVVGIDGSTAAITAALWGTDEAVSAAVPLRLISVIKTTHPcpedyerdlrhaVTSLRAAQAAVAATGKPiKVDTDTPRGPAGAVLVEASR--DAGLICVGSAGIGRYARSILGSAASELAEKAHCPVAVIRPD +>tr|A0A1L5PCH5|A0A1L5PCH5_RHIET Universal stress protein A OS=Rhizobium etli 8C-3 GN=AM571_PC00068 PE=3 SV=1 +GRIDTVAVAWDGSATLARALTGARVFLDK-ASRAVLISITDDKAIDADLrDRFAAVIRGAGLAieIVDAQSQGDPVATKIQSVAAQSRADLLITGGFGHSRLRELILGGVTRSLLNGLEVPVLL---- +>tr|A5UUW5|A5UUW5_ROSS1 UspA domain protein OS=Roseiflexus sp. (strain RS-1) GN=RoseRS_2033 PE=4 SV=1 +---MNLLIYAGPGPWRNEALATAAQFAGRVATLVTLVTGGGMSNA-PLLDDALARLRLPPDVEVRRRVVEGTPQEAIMTVVDEMTYHLVIFGRFQ-RPLERLLPLRRSDALTRRLRSAVLRVHG- +>tr|R7KMG7|R7KMG7_9BURK Universal stress family protein OS=Sutterella sp. CAG:521 GN=BN692_00345 PE=3 SV=1 +----HVGLSVDDSPFGPKCADYLIAHRHFFGkdATFEIINVVPDDPlyapdfvnegpippqmtweeiqgleFEASVKSPVEKFDIAGV-PVKAVKLIGNPEDVLPKYADE-HLDVMVMGTHGKGALRSLVFGSSTRAMIAATNLPILVVPNV +>tr|C6XIF3|C6XIF3_HIRBI Uncharacterized protein OS=Hirschia baltica (strain ATCC 49814 / DSM 5838 / IFAM 1418) GN=Hbal_3092 PE=4 SV=1 +--TRKFLTLADDTQECFSAILFAAMRAKRVGAGLVIMRAVQVSGMghwrgldedmrteamdnaLAEVKSIARLIKDRIDIEAEIIVEIGKPEQAISRITNkDKTIKVIVLGSGSGRAGPGPLVSRIGRGkALTERPVAITIIPGN +>tr|A0A0K8P8C2|A0A0K8P8C2_IDESA Serine/threonine protein kinase OS=Ideonella sakaiensis (strain 201-F6) GN=ISF6_0199 PE=4 SV=1 +-----VMVALPWRDASDATLYALRESVARSlglrpGARLACVSVLPPGGARGgpgpdgdgdgaagvpshrhllaRLHEWAAPLDQDAH-PTSCHVLEHgDVARALLDYAVGNHVGLLVMGAATHGLALQPVVPTLPIRVAMAAPCTVMLVKPA +>tr|A0A0S8BK38|A0A0S8BK38_9PROT Uncharacterized protein OS=Acidithiobacillales bacterium SG8_45 GN=AMJ68_03980 PE=4 SV=1 +-----ILAAINLSSGD-ALNIEILRRAQQMaglqHSYITVVNVT-AVDVGMasgernaqlineqlvkarkKIATLIPRTGLTAA-QVGINVLIGdDPVGVIHRCVNDYGIDLVVIGCPEKNRLRKFIHGSTGYKILTSVKRSVFVVHAP +>tr|A0A0S8KWX3|A0A0S8KWX3_9PROT Uncharacterized protein OS=Acidithiobacillales bacterium SM1_46 GN=AMJ72_13555 PE=3 SV=1 +-----IVVALDSASGGrvETINRALLDATLRLarmqPSMITVLTVLAPQDTGMadgareaqiinasyhsarnRINRLLPPSGSMSA-PIGINVRTGNVVEAISTCVADYGADLLVIGARERNALSRFLLGSTTYKVLTTLSCPVFVVRER +>tr|A0A177Q4K7|A0A177Q4K7_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium SCGC AG-212-E04 GN=AYO41_00930 PE=4 SV=1 +-----IMVAIDTVHPDDERHAALRRATEQVlagtaEFRLVCISVLGLFGDAGgtvpadadadlhlehliRLRHWVDPLKLPTQ-RLSLHVLESlSPSAGLLDFARRNHADLIILGAPGAAQRGMAWWRSVASTVAANAPCSVHLVRVP +>tr|M7MXH6|M7MXH6_9BACT Universal stress protein F OS=Cesiribacter andamanensis AMV16 GN=ADICEAN_03732 PE=3 SV=1 +YPIKRILVALDLTDMDVTLIQYAAFIAKNTPAEkIYFVNIIRNFHIPesvlkefpglmdtaiaerkeKMKAVVDAHFHAGEailtRFKIQYLVKDGAPARKLLQMSQDSDIDLIIAGRKVSLEG----SGVLVQRLARRAACNLLIVPEG +>tr|A3I339|A3I339_9BACT Putative universal stress protein OS=Algoriphagus machipongonensis GN=ALPR1_14244 PE=3 SV=1 +YLIKKLIVCLDQSPLDQTLVQYAEFIASVNQTKkIYFVNVIKNLTVPkevieefpnlvenminerkeAMENLVKENFKSTKGISFNYVVKEGSLSKKILKLADEKSADMVLIGRKVELPG----TGVASLRLARRASCSLLIVPEG +>tr|A0A1M6G641|A0A1M6G641_9BACT Nucleotide-binding universal stress protein, UspA family OS=Tangfeifania diversioriginum GN=SAMN05444280_11046 PE=4 SV=1 +YQLDNILVCLDLSDMDDSLIRYSNYLVEKFKPTtVTFLHVMKSYDIPeeiisafphlnepisevvkeELTEKINELFKHDKTTKTIISVKEGTTTDTIVRYAREQNITLTLMGKKIGYEG----QGGIVRKVLNIVPSSVLLISET +>tr|A0A1S1YZM7|A0A1S1YZM7_9BACT Uncharacterized protein OS=Flammeovirga pacifica GN=NH26_08910 PE=4 SV=1 +DKTQTALLPLDLTYIDDAIISYSLKASPLSQVKkIILMHVLKDNTEKdeveykgkllsrhdmaeaKMRDLVEKHKDLNDrNIVFEIHVSASNdPTSKILKYSKKKKVELIIAGKKNIAEG----SGTIARLLTRYAFCTVLTVSEN +>tr|A0A1S1Z4W5|A0A1S1Z4W5_9BACT Uncharacterized protein OS=Flammeovirga pacifica GN=NH26_19270 PE=3 SV=1 +SVFKRTIIALDGTDKDIPLLKHASKYIQRNEIEkIYFIHVQESLDLPeeviekypdmlspldesikkDMEELISEHLPFAKELNHELMIEEGDPAETIIKISKRKQASLVILGKTDKKNK----TGAIARKIASFSPASIMFAPEL +>tr|A0A0D3CND1|A0A0D3CND1_BRAOL Uncharacterized protein OS=Brassica oleracea var. oleracea GN=106292758 PE=4 SV=1 +REPTRVMVAVNESTikgkphpsiSSKRAFEWTLEKMVRSNAsdfKILLLHVHVVDEDgfdevdsiyaspddfkdmresnkskgLHLLEFFVNKCHEFGVS-CEAWIKKGDPKDVICQEVSRVRPDLLVLGSRGLGRFQKVFVGTVSGFCVKHAECPVLTIKRN +>tr|A0A077KJ32|A0A077KJ32_9FLAO Putative universal stress protein OS=Chryseobacterium sp. StRB126 GN=CHSO_2369 PE=4 SV=1 +--MRTILVPIDFTPTTENAVKAAAEWAKYYEyQNIILLKIAGESEFDylhiaeghsfvneesvnsllerteLRFDQLSQVVAEISPEvKVSRLLSDWAITRSINEVLKNePSIEMIILGSDDSTSSNESFVSENIIRIARTSPVKALIVPNS +>tr|A0A1C4DI76|A0A1C4DI76_9BACT Nucleotide-binding universal stress protein, UspA family OS=Chitinophaga costaii GN=GA0116948_105289 PE=4 SV=1 +--MKTLLIPVDFTTTTDNAVTFGGAWAKRYDyERIILLKTFYDNVFDnivvsaeyapvnqeyraqerqearEKLDQLCERLRSLaGPGvTVVTAESEAPLLRSILELVQAERPEMILLGSDDYKHTTGSFIAGHVISIAKASPVRVLIVPAS +>tr|A0A0P0GHF1|A0A0P0GHF1_9BACT Universal stress protein family protein OS=Candidatus Xiphinematobacter sp. Idaho Grape GN=AMD24_00191 PE=3 SV=1 +PMYHNILIPLENSIADSTILEHVCRLAHSIGGYLHLLHVASGWVARnydqlnlteseemkndlRYLESVAQALRKGGL-ECSYELAMGEPSNEIIRIAKEREVDLIAMSTHGHRFLGDFIYGNTVDRVRHLVGVPVLLLKAA +>tr|F8L8B1|F8L8B1_SIMNZ Putative amino acid permease OS=Simkania negevensis (strain ATCC VR-1471 / Z) GN=SNE_A11570 PE=4 SV=1 +-KYQNILVPTRG-GRETETVQMACEIAKIHGAKVTALHVIEVPFSlpletplyhrtivaESILKRAEAIGREFNIRMDLKVINARAVDVAITDLVEKEHYDLLVMGTTMTKGGTAKGYGGVVERILKNATCPVWLCFSA +>tr|H0EBI1|H0EBI1_9ACTN Amino acid permease-associated region OS=Patulibacter medicamentivorans GN=PAI11_42120 PE=4 SV=1 +-AYGSILVPLLGTALDDDVVQTAGRLAGGDdetdieegYAVIEAVWIHVLPMSlpidgpladgrikeAKqALSRAKAVGEEYeGVRVATSAVRARALGKAIVDEAARRGCQAIVMVAPPPtgrarsgragaalGArgg-RGDVLNEASRYVVDKARCQVILTAPA +>tr|I0INL6|I0INL6_LEPFC Amino acid permease OS=Leptospirillum ferrooxidans (strain C2-3) GN=LFE_1174 PE=4 SV=1 +-VPHRNILVATSPHAPSPILHDIAKIAKSDKARVTVVTVLEIPLSlplnaplpeeeaiaQNTLELCQAIGVEGDILLDTLLIRSRSIGDSLVQVYTRHKADTLVFNDTNSsvsKSidaAIVRSGVPVTVWKIQSIMGRSGKKPGD +>tr|A0A1Q3NC28|A0A1Q3NC28_9ACTN Universal stress protein UspA OS=Solirubrobacterales bacterium 67-14 GN=BGO23_10950 PE=4 SV=1 +-EYKSVIVAFPADqPFSEEVMATAAKLTSDRRRGIHITALLTVPTHlplessmakeekeaQSKIERAKLI---AGLRVSGRVerVRPGQEGYFLARQARTSKAAAIVIGLNSRrgVPq-YGKTL----ETVLRERPCRVIVVSED +>tr|A0A1Q3NC98|A0A1Q3NC98_9ACTN Uncharacterized protein OS=Solirubrobacterales bacterium 67-14 GN=BGO23_10940 PE=4 SV=1 +-DFHNILVPIFGTRIDDDIVSTAGRMAAEGdpeqsdaHAVMTILYLIEIPLNraikdplpeevadaAQrATKRAKEVADEYeDVEVRVEIERVRKKGTGIVFAARRLGVDAIVMGAEPPspikggarlGGigdYRPEEIGPITAYVLKRAPCRVLLTAPG +>tr|A0A1G0DTV8|A0A1G0DTV8_9PROT Universal stress protein UspA OS=Gallionellales bacterium RIFCSPLOWO2_02_58_13 GN=A2Z65_06135 PE=3 SV=1 +RLYRNILVALDSSDYANAAMRDAAELACMAdAPVITGSHVYAAKLHDmrfrqmegglpeqfrqeqelerqrdvhddlitrglsiitdSYLDQAANECARLGI-EFKRSSLEGKNYRELVRETNSGRYDLLVMGALGLGAIKGSRLGTVCRRSARRSAIDTLVIKNT +>tr|A0A1Y3LUR6|A0A1Y3LUR6_9MICC Uncharacterized protein OS=Arthrobacter agilis GN=B8W73_09955 PE=3 SV=1 +KRNRPIVVAVRDTATGGPAVLWAARRAESLGVPLTLVHAVPDPALMPpgspygdvvvggrevLRAEANRISADFPALHVGTYLHCGDVVEALLGLAA--ESPLLILGSDRMDAVSGEFRGSVSLQVALGSRVPVVVVPSD +>tr|A0A0J1DBL1|A0A0J1DBL1_9BURK Uncharacterized protein OS=Massilia sp. WF1 GN=AB595_11200 PE=4 SV=1 +KPYAHAVFPSDFSPDSLDTLQAALRLL--PATRLTIVHAFHVPGEgqmraarvrdeaigacrrkaelaaQEAFAALAARLQPHPA-RLSLVLLPRPTGLAVAEYVNAVDADIIVLSGSQRWLVDDWSWQHRARELIEKTSSDLLMVTP- +>tr|A0A1M3QTS6|A0A1M3QTS6_9SPHI Uncharacterized protein OS=Sphingobacteriales bacterium 40-81 GN=BGP13_06525 PE=4 SV=1 +NNFYNILIPIDFTVKNKWAITKAIELANSFNCNIHLVHVVFKPVFPlinidasnftpyashINMQTCREKLAElkaiykkqmVGEGEIEISLLQGHPQKQLKQYIENYKMDLVVMGLAKFNLFDRIISSISISLLAKKISVPILAIRSS +>tr|A0A009ZYP5|A0A009ZYP5_9GAMM Universal stress family protein OS=Acinetobacter sp. 479375 GN=J500_0057 PE=3 SV=1 +KAPTRFIFAYEYSPTCVKMMHRIAQSDLLRTLQCHLLYVGDHP---QVLKDPEEFLSHAGI-EVVTVYRYGDVAENILEYQREHGIQMIVLGAFSHSKIHQFFLGSIATSIFRNATVPLLVAK-- +>tr|A0A0X6ZKR0|A0A0X6ZKR0_9ENTR Universal stress protein OS=Enterobacter cloacae complex GN=ABF69_0212020 PE=3 SV=1 +MSYSHVLVSVAVSPESHQLVARAVSIARPHNARISLITLAAEPEMynqLAapmledirevLQEETQQFLRDlaekAQYPIHETVIATGELNAHILDMCRKQQIDLVICGNHNHSFFSR--AACAAKSIVASSQVDVLLVP-- +>tr|A0A1S8CMI6|A0A1S8CMI6_9GAMM Universal stress protein OS=Rahnella sp. J11-6 GN=BMI79_06440 PE=3 SV=1 +MGYYNVLVAVAVAADSHRLVEKAVSIVRPYNGQITLVSMIANPEIynnFAgpmfgdlralMEEETLLFMEElrsrTDYPIDNTRIIHGELGDCLTYANQRQPFDLVICGNHSDSMLSK--VTCSAVRFINTSRIDVLIIP-- +>tr|A0A0E4ANK4|A0A0E4ANK4_BURCE Uncharacterized protein OS=Burkholderia cepacia GN=XM57_23745 PE=4 SV=1 +-MSKTVVVAINHNFT-DSFLASALETARHCDARIAAVHVVDLTHCYaglgdsnyglvvgamlaygrAALARAMTTLNDNPR-GADAHLLtlpvRGsHIGREIASVCEASNAELVLLGARKRVWW-QVIGEDVAATLRKATRTPVQIVRAA +>tr|A0A1P8KC54|A0A1P8KC54_9BURK Uncharacterized protein OS=Rhodoferax saidenbachensis GN=RS694_14050 PE=4 SV=1 +-MYRKILVLVDNRQVTQSAIDQAIGLAQVHRADIFFFSVLPNYVYPavdmlpvadmsaddfraqaseeasRMLSAASAWAERCGVHNHRAMGAGADGAHCVAEAAVKRHCDLIVVGTEEQNAVVRLLSGSIVPGLISAATVPVLVCRE- +>tr|A0A0R1Q637|A0A0R1Q637_9LACO Uncharacterized protein OS=Lactobacillus nagelii DSM 13675 GN=FD45_GL000139 PE=3 SV=1 +----------------ITALERTAEYANKNNIQLDILYVLDPAIAGfgntqielsseslyhleeksiGQLEIIKRRLIISGSSiyQVHVHLRIGDPRIIVAqEFPTEYQNDLIVLSSSRKNHLQRFFTGSVSSYVIKNAQADVVVMH-- +>tr|H5SES2|H5SES2_9CHLR UspA domain protein OS=uncultured Chloroflexi bacterium GN=HGMM_F17E05C18 PE=4 SV=1 +-PPQEVLICVGGIGYEVTAERIGLQLARHFQAHVTLFTVIPHADLDyplvhqvqeheqdlwetdtpigRALRRGLEQAHSLGL-EVAVKVRHGEVVEEILKEIRQHKPQLICMGSPFSSqSLRHYYMPNVTAEVAESGLAPVLTAR-- +>tr|A0A0C1KWP0|A0A0C1KWP0_9PSED Universal stress protein OS=Pseudomonas sp. C5pp GN=RR51_05970 PE=4 SV=1 +AMPANILVAVDVAKADLaqqalnhALVEAGRQLASPCNGQVHLLSVYDLPlamlanpdlaaPWAEQVRESLQLpfdelADIHGIPYAQRYFIEGAPLRVIQSLVPTLKVDVVVVGVVQPRRWAK-LIGDTTERLVNDAPCSVLAVRPP +>tr|A0A150XP44|A0A150XP44_9BACT Uncharacterized protein OS=Roseivirga ehrenbergii GN=MB14_15415 PE=3 SV=1 +FEVKNILIPTNLTDDYTAAMPDLLKFAESYNAKLTLVYVNTQAHFkttLQANKLKVEFLEKHGLENHAVEIFnAKSINRGILYAAEFFNSDMIALFSYHTENIKTLLVGNITEYLITKSKVPVLTLN-- +>tr|A0A150XBG0|A0A150XBG0_9BACT Uncharacterized protein OS=Roseivirga spongicola GN=AWW68_09685 PE=3 SV=1 +FAPNKILIPTNLEDDCSQRMSDLLALAEKFNSELQFVYVNTPAFFhtsPQIRKKSHLWFQRNGLKGYEIEVFnTKQLQKGILNAADFYESDMIALFSKHSESIKDLIKGNITEYLITRSDIPVMTFN-- +>tr|A0A1M4XRG6|A0A1M4XRG6_9DELT Nucleotide-binding universal stress protein, UspA family OS=Desulfacinum infernum DSM 9756 GN=SAMN02745206_01092 PE=3 SV=1 +-LDKCVLVAVDGSERCLQAVSRFASFLRgRKDCCFVLLHCVQQNLLLypgelwdaetslriakdtqekicrSITEPCRKALRETHFAeeqvETVCCFDSLDPGMDILRTAERHKIRTIAVGRRGLTPAENLLLGSVSSRVAQYAEhRTVWVMDP- +>tr|A0A1N6L1Y7|A0A1N6L1Y7_9BRAD Nucleotide-binding universal stress protein, UspA family OS=Bradyrhizobium erythrophlei GN=SAMN05443247_09407 PE=4 SV=1 +-AFKEIVIAWDHTAPAARAVGDALPLLTNAT-QVRIVTATDRVTDaqRGSGAALRRHLAEHSIEARLDTIRIEgsSVGKVFEAYIDQNAIDLLVMGGYRHSPVNEWFWGGMTNTIINDPPCWVFL---- +>tr|A0A0S8FD65|A0A0S8FD65_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium SG8_31 GN=AMJ59_16185 PE=4 SV=1 +WPPKKLLVGLDPVHDGSVLVERAAELGRRFGATIILFDCVQNQYVSrryfrdghalnharqtlvkghrDRLERLAQRMIVGNL-SVIVDATWDAPLdDGLIRAASRHDADWILVGIGYHRIPRLPFLASTDGSLIRQATCPLLLVQQ- +>tr|A0A0C5V4K3|A0A0C5V4K3_9GAMM Universal stress protein UspA and related nucleotide-binding protein OS=Gynuella sunshinyii YC6258 GN=YC6258_02377 PE=4 SV=1 +FRINNVVVLIDPAEDNQSALKKAQIITTTVNGKLTLFASGYNSTLAnhsnvnpensekakaaflqrirANLEEKADTIRQEGL-SIECVAVWDKHPsQAIIKYLETNSVDLVIKNTHHQNVMQRTFFSHTDWDLIRYSPAPLLLTKN- +>tr|W9V8E0|W9V8E0_9GAMM Universal stress protein E OS=Nitrincola nitratireducens GN=uspE PE=3 SV=1 +NSLSKILVNITQEQDKYLLPEKAIRLAQALSAKIEFFKCGYQPHYSsmnllgndileklqhnrlrdleGSLNELLATLKKDYD-NLSVDVAWDRGIaEGLLTKVERSNPDLVLHEVAEHPHLLHRLLVPHDWQILRECMAPLMLCKS- +>tr|A0A1N6PXZ9|A0A1N6PXZ9_9GAMM Universal stress protein E OS=Marinobacterium stanieri GN=SAMN05421647_102114 PE=3 SV=1 +ESYARFLVHLKQDEHRGELLVKLRKLLQA-DSQVELFSHHYSAAVEgstlfdpekhqhaiqsllrqieKGLQSHTDKLEQLGV-KAGADVSWGRDEaETLVRKVMRYKPDLVMHAPDTHPDLLQRILGAPEWRLLRLCPAPLLLSKK- +>tr|A0A1B8RW00|A0A1B8RW00_9RHOB Uncharacterized protein OS=Leisingera sp. JC1 GN=A9D60_23785 PE=4 SV=1 +-PYRRILVALETGDTlVDEILSTAVEFSHEANSSIRFLTVVSHVPEEvsdiallpavdpnipldhrekiakaevaKAKSAGRHLLDSFePLGESKHVVRRGVLEDEIIKYATQWPADLLVMGAHNRSWFKKILSNPSSTRVLDGVGCAVLIVP-- +>tr|A0A1F2VER2|A0A1F2VER2_9BACT Uncharacterized protein (Fragment) OS=Acidobacteria bacterium RIFCSPLOWO2_12_FULL_67_14b GN=A3J29_18280 PE=4 SV=1 +-PFRRIMVCVDGSEMGETVVLHATMVAAAFGAPLTILHVLEteshgdtppsdPLDWGVRQRAARAYLDRlvslAGHIDVRAELIQGRAAEQICCWALQHGADLTVLASHGEHGRSEWTLSSTARKLVDGVPGSLMLIPAD +>tr|F2NEY0|F2NEY0_DESAR Uncharacterized protein OS=Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2) GN=Desac_0433 PE=4 SV=1 +---MKILFAGDEHPYSAYALKEVIRLARNTWADVTMLAVAPGDKGvpksdhlliqalqgyrehflksseaegspyarkewrYEWLPLKNGVWEELlvcrgDKRDVRVCFRVGNIVQEIVAEAKDEETDLIIVGCTKGR--ECIWQDAAAvpQKVVNDADCSVLLVKEE +>tr|A0A1Q6DKL3|A0A1Q6DKL3_9DELT Uncharacterized protein OS=Desulfobulbaceae bacterium DB1 GN=BM485_10700 PE=4 SV=1 +---MRIIAAFDHHSYSERIIADLADIAANTWADITILGVQQADGGggpddyfagtfrhyreeflrrvsggelpyggvtgyEEYHSLGKGRWEINnqgwegdVRKKLLVRIRTGDPMKEILAESREQKSDLIILGCTKGL--DCQWQGEVDlpRKIAAKAGCSVLVIKEM +>tr|A0A1S8WKA9|A0A1S8WKA9_9TREM Universal stress family protein (Fragment) OS=Opisthorchis viverrini GN=X801_09324 PE=4 SV=1 +SSARSVLIAVDDSPPSKNAFKYYMRWLSRSDDAVTLYYALEPSSLPsvpltnlgtiphdewskiihsklecvrRLESQYVTDLQTKGLNYQFVYETADQVGKSIVSKAEKYRARLVVMGSRGLGALQRTLMGSVSDYVLHNASTAVCVIPHN +>tr|E4U688|E4U688_OCEP5 UspA domain-containing protein OS=Oceanithermus profundus (strain DSM 14977 / NBRC 100410 / VKM B-2274 / 506) GN=Ocepr_0502 PE= +RPFKHFLVSTALADPSRRALEFAKKIADAVGARITLMHSVEPIAEppipihmpdpryieerQALIEQLAKQLHEFAAPyGARPLLKEAKPVDAICQVVAEEDIDAVFIGKSRQSRF----MGSVTREVLERAQVPVFVHP-- +>tr|Q12XP0|Q12XP0_METBU Universal Stress Protein-like protein OS=Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M) GN=Mbur_08 +--YKNILVPIDEKQLSKRVIDHALHVADKESGKLIIVYVERKKTLecifpkelakkmmvivkeniESNMEYALENAKISGIAVENIILDNDEIAKDLIRISEEKSVNLTVMGSES---LKARSPWEYhpmayrSRYRTCSCHHRRRLIHAF +>tr|E6VTX7|E6VTX7_DESAO UspA domain-containing protein OS=Desulfovibrio aespoeensis (strain ATCC 700646 / DSM 10631 / Aspo-2) GN=Daes_0040 PE=4 SV=1 +------LVCVQETKRSQAMLDRAVRYAKACDCPSTLLSVAPDEAGresaQRAVNEADAYFREHGVTPHELLVEVGNPAEIITEIGY--DFSLIVMAESAKPWFAKTFS--VAHEVAARARNSVLIVK-- +>tr|M1WTF8|M1WTF8_PSEP2 UspA domain protein OS=Pseudodesulfovibrio piezophilus (strain DSM 21447 / JCM 15486 / C1TLV30) GN=BN4_12302 PE=4 SV=1 +------IVCVQDTDVCWKMLPKAIRYSITCDCPISLLAVAEDEEGkasaQKAVEKAAEMYRQAGMEPHELLVEIGDPADIITEIGY--DFSLIIMAESEKPWFAKVFS--VAHEVAAKARNSVLIIK-- +>tr|A0A1B7XDM5|A0A1B7XDM5_9DELT Uncharacterized protein OS=Halodesulfovibrio spirochaetisodalis GN=SP90_08160 PE=3 SV=1 +-MYKKMLVAFDGARTSMDIVRQAAQFARSENSMVDIVTVCPEYQGDlrihgdtsvlydmyesirNALNEAVQQCEEIGVK-AQGHFCVGNPSDILVEQVGALGSDIVALGTHSSQLLQSIVVGSVAGTVVQQTASDLLIITGN +>tr|I5B460|I5B460_9DELT Universal stress protein UspA-like protein OS=Desulfobacter postgatei 2ac9 GN=DespoDRAFT_02417 PE=3 SV=1 +TDIKTIMACVDLSDYSPMTLGYTLGLAQQGDIKITICSVIPLREVtpvfmtgtiyhcREDTTEYLEELKENRKaeinalinklimercpqfsSKIDIRVSTGHPADAILDMVERINPDLVVMANKGRSNLSNFMFGSAAEYVFRYCTAPLLSVRD- +>tr|A0A0J1GRW3|A0A0J1GRW3_9GAMM Universal stress protein OS=Photobacterium aphoticum GN=ABT58_02935 PE=3 SV=1 +MNYKHVMLAVNLDDNAPFLVQKAAQEAKLHGALFSVIHIDPDFSAlyegvrefdasnetaeqSESVLAMTELLAGTDYPVHKHIFYAGYVEDQIIRAIETFEVDLLVIGHHE-STIFRQLTMSASEPLLRRMPCDIQFVKLE +>tr|S5DP01|S5DP01_9ACTN MedDCM-OCT-S31-C51-cds20 OS=Candidatus Actinomarina minuta PE=4 SV=1 +YPYKTIGLLINSNFDENSSNSIAFDLASAMSANLVAININQPKFLqqdnekqlAGTLEKLQDLALSHEV-QLDIETHEGNEAKIFSEQTS--KFDLSIVSSSAT---QTWQGRKIVEFVSKNSKCSVLYIP-- +>tr|A4Y6Q5|A4Y6Q5_SHEPC UspA domain protein OS=Shewanella putrefaciens (strain CN-32 / ATCC BAA-453) GN=Sputcn32_1915 PE=4 SV=1 +NKANTILMAVDLDASNpqkkslnDLVVEQAKMLANATGAELHLAHVIRVPPIlrdmdviniheviESAHQKHADKLKVLGLAPENIHLIAGDPELCLFELSCRLKSRYLVIGARQRQGLLGYVLGNTAEAILSRMRSNVLVVPKN +>tr|A8G0E4|A8G0E4_SHESH Uncharacterized protein OS=Shewanella sediminis (strain HAW-EB3) GN=Ssed_3963 PE=4 SV=1 +HRGNAILMAVDLGSDNvlkqqlnQAVISHGKALAKATGSKLHLAFVIRVPRVlrdmdlintstivKDAYQEHQKQLAKLNMDPECIHIIAGDPDLCLYELSCRLKARYLVLGARQRQGILGYVIGNMAESILSRTRSNVLIIPAD +>tr|E7QZL0|E7QZL0_9EURY UspA domain protein OS=Haladaptatus paucihalophilus DX253 GN=ZOD2009_21097 PE=4 SV=1 +-MSETILLPLRNYRPWAEAVAGAAAAVESSDVTALLLHVFDEEERASTRAnidddgsmtvddlaarksgivAAREILQDAGV-SVEVRGREQveTTADSILTVSDEADVDRLYLYGRKRSPTGKAVFGSTLQRVLLNATVPVTVVPSN +>tr|A0A0W1RE08|A0A0W1RE08_9EURY Uncharacterized protein OS=Halobacteriaceae archaeon SB9 GN=AUR64_03730 PE=4 SV=1 +-MSERVLVPASRFDPWARAVADTVTSMEAsATAVPHLVHVFDEIEWNSTVQqsdaatvpdpdelaerksaimAAATIFDDAGF-DYTVIGIESeTPSRALLDLVDEANIDRIYMYGRKRSPAGKTVFGSRLQTILANSPVPVIVLPAD +>tr|A0A1X7L5D7|A0A1X7L5D7_9BACT Nucleotide-binding universal stress protein, UspA family OS=Dethiosulfovibrio salsuginis GN=SAMN06275492_1478 PE=4 SV=1 +-SL-SLMNAMDFSNHAINAYEKLLELLSGEPNsfkKLTLVHIHDDKNLElllkvanaeqieplieiekKRLEKMKEEALRAGIESVNISMKKGIPTESILDLIEEEHTSLVVLGAQGQGASEKYRVGKNAYRIAQEAKCCVLIVP-- +>tr|L8JKF6|L8JKF6_9BACT Uncharacterized protein OS=Fulvivirga imtechensis AK7 GN=C900_05326 PE=3 SV=1 +SDYNTIILGLDTERDskdnFSQAAAYLNDLADSLGARIDIVNIVKPGTNDKVkiERKLIDFAARYGIKDHSVTIVESdDKEKGLINFARTHSAGLLAVFSHAEDGFFRIFRDNLSEELTMSSDVPVLTIN-- +>tr|A0A0D3LHX3|A0A0D3LHX3_9BACT Universal stress protein UspA-like protein OS=Flammeovirgaceae bacterium 311 GN=D770_16095 PE=3 SV=1 +TDIRNIVLATDMNDKAHNGLRHIKVLADRLRAHLHLVYVTKSGKIQQRRSDVETYARNQGLANYTIEAIEDsDIEDGIKRYAAKVGADLIAVITHGRNGLSAMLSHSVAEDVIREASVPVLTVN-- +>tr|A0A1R1IPA4|A0A1R1IPA4_9CAUL Uncharacterized protein OS=Brevundimonas sp. ZS04 GN=BJP32_00545 PE=4 SV=1 +SDQPVILVPLDGMADALPALSVAKVFSGLEHAAVRILHVAEQASAAEELAPRLGLAAEDLR-GASLETRSGEPAAAILAAAGDLLARLIVLCTHTAPGSPAGKVGGTALSVLRGASCPVILVNP- +>tr|A0A1F3RP01|A0A1F3RP01_9PROT Uncharacterized protein OS=Bdellovibrionales bacterium GWA1_52_35 GN=A2X97_16030 PE=4 SV=1 +ERFSMVYVPLDRNEASKQVIPLASALAEAADATLCFIHAATHNEAATDLLEHLHVTRGQIR-NAMFDQFPGRPEDVIPATVNQHPHSIIVMPMSAHPEGGIQELGPVSLAVIKKADCPVVFAPP- +>tr|D4YQK1|D4YQK1_9MICO Universal stress family protein OS=Brevibacterium mcbrellneri ATCC 49030 GN=HMPREF0183_2211 PE=4 SV=1 +----VVVVGVSDTSNSPKALAWAMDMVRARGGRLIAVRASTAGGGFnayasppttgrRPLEPEVAKLKADvisvlgaeavegPESVVDVHVFRGETSRVLRNVSK--NASLLVLDAPRNPVTQ----PLLAPRVVYNVDCPVVMMPPT +>tr|A0A062V7G2|A0A062V7G2_9EURY Universal stress protein UspA-like protein OS=Candidatus Methanoperedens nitroreducens GN=ANME2D_01773 PE=4 SV=1 +--GKSMLLPVASRELvTDELITLTSCLAKFYEHRVEIFHVVELqrwytlpwkelytmRhHGEEEMMPVAKVLREQGI-DVDVRAVISEsSINAIPKEAAIGRHSLALMRASRRGILKQVVYGNPIERMLSSILCDVLIWRP- +>tr|A0A1G0LBI3|A0A1G0LBI3_9DELT Uncharacterized protein OS=Geobacteraceae bacterium GWB2_52_12 GN=A2X80_04820 PE=4 SV=1 +--PRRILVPLGRIVAePAPRIRFIAALHASFHGGVILFHLAADtlPeSTPRDITLFRSELHRHHV-ATLERFATGHIGRGITAEAATGRNDLIVLGASERSILRQLFYGNPAGDVMHQPPCNAILFRA- +>tr|L0IFD4|L0IFD4_HALRX Amino acid transporter OS=Halovivax ruber (strain DSM 18193 / JCM 13892 / XH-70) GN=Halru_2090 PE=4 SV=1 +REFdtSRILLPTAGGPDSDLSADVARTLQRTNDADVELLYVVDDPsERDEGEAFLSAWAEEHGLSDAGRTIDTsGDVEEAIRRESS--DRTLLLIGATERGLLSRLVDRSLVYDVVDEVECSVLLAERP +>tr|V5A6V2|V5A6V2_9ARCH Amino acid/polyamine/organocation transporter, APC superfamily OS=uncultured archaeon A07HR60 GN=A07HR60_01332 PE=4 SV=1 +PE-dsiGTPVALAGPGPHAPAAAERAAEFAEVNDSTPVLLNVQSPGhsaglsAEERGHRAIEWIADRAGLESDrydAEVVVAd-DTEAAIVEAVQ--AHGTVCVGLSEKSDNSRILFGSIAERISQTRAGNVGIIRGA +>tr|L0AMJ0|L0AMJ0_NATGS Amino acid permease-associated protein OS=Natronobacterium gregoryi (strain ATCC 43098 / DSM 3393 / CCM 3738 / CIP 104747 / JCM +DGFddaDEIAVVANRGAYDPLKLLFADAVAEETGAELNLLQAIAADapetQRETIERYHEELFSLLTVPARSTVIETDDEIAGLTRFVG--DADLLVTG-VDRTGMSARFLGRPGNRLVERVDTTAVMVQTR +>tr|A0A0E3LNZ5|A0A0E3LNZ5_METBA Amino acid permease OS=Methanosarcina barkeri MS GN=MSBRM_2633 PE=4 SV=1 +HLPdsiHKILVGY-NGKEnSVYGLSLAEKLAVNTGAGIEIISIISPDesqeNRQKITDELESLVGkISSIPVSFRVLTKYSIEDALLEASN--NNDLTIIG-DSSERFKISLLGTLSQRIARHSKKPIVIVKKS +>tr|L9WU80|L9WU80_9EURY Amino acid permease OS=Natronolimnobius innermongolicus JCM 12255 GN=C493_15308 PE=4 SV=1 +RGTaeiDDIVVATETGPYDRAEVELADAIATVTGASLTLVKAVPDDaseeAVASARGYLDELTAVLSSPAETELLRTADVDAALVDRAD--RTDLLVMGAPTHPDRVSAFFGRTTDAVVAETETSVLVVKEP +>tr|A0A133ULK7|A0A133ULK7_9EURY Amino acid transporter OS=candidate divison MSBL1 archaeon SCGC-AAA259I07 GN=AKJ36_01545 PE=4 SV=1 +GREkiGRVLALVGEGPNAPLAVRRAHELDKkAGVGELTIVNVQKGEkeeeeLQNQGMRMIEKTTNKARLESSeykSKVIIGe-DVEKAILKEVQ--NYDTICIGGTEHSVLSHTIFGSLPEKIGETAEGSVVMVKGY +>tr|M1Y0T9|M1Y0T9_NATM8 Transport protein (Probable substrate cationic amino acids) OS=Natronomonas moolapensis (strain DSM 18674 / JCM 14361 / 8.8.11) +LHYdtaSHIGVVTDEGPFDPPKVGLTDALAMAVDGTVTFYFPMPVDapesRRNTVEDYLSELADLCEAPVETKIIEPGT-DDAMERAAR--ESDVLIVS-GVQRGLTDRLFGRasR---VTAGSKHGTL--VVY +>tr|A0A0W1RMB3|A0A0W1RMB3_9EURY Amino acid transporter OS=Haloferax sp. SB29 GN=AUR66_19010 PE=4 SV=1 +LGYdepKQVMLTGATSPYSPLAVSIAERVAAANRGTISIQNTTEESdepdLWEVIDEYRSDLAAVLSVPVRTETL----FTDGGR--RI--HPDVVVQP-SPDRGIRTAVHGTL--SSTPSHNCTTLTVYSH +>tr|Q2LGP0|Q2LGP0_9ZZZZ Amino acid transporter OS=uncultured prokaryote 2E01B PE=4 SV=1 +LGYdepDRVVLTGDGGPYPPLVVNVAAAVADANNGEISLWRGDRPAt-ADEAGDYRAELTDLLSVPVAPTPTEWEPRTDGGV--PA--EPDVVVHR-GPDLGLRGAVDSG---GARPAVGCTTITVYPH +>tr|A0A238XU53|A0A238XU53_HALVU Amino acid/polyamine/organocation transporter, APC superfamily OS=Halorubrum vacuolatum GN=SAMN06264855_1232 PE=4 SV=1 +RGFdpSHVLVPTAGGSDSDLSAEVARVLRDGRGSEIELLYVVDDEaKRAAGAEFLGRWAQEHDLGNANLSVDVdGDVEAAIARRSR--DSSMVIVGATERGLLSRLFSGSLVYDIVNEVDTSVLLCERP +>tr|A0A1Y3GB49|A0A1Y3GB49_9EURY Amino acid transporter fused to UspA-like domain OS=Methanonatronarchaeum thermophilum GN=AMET1_0294 PE=4 SV=1 +RGFnptkhNKILLPTrLSS--kIGLTLDLSSAIARKGNGFIELLRIINPRassnEIEKIKEFQKRSEKRIKEESSSRIIKSKDVTKALINESR--KFDLVVMSASQESALKGFLFGTIPNEVADKTDTSVLIVQEK +>tr|A0A1F8R3D7|A0A1F8R3D7_9CHLR Uncharacterized protein (Fragment) OS=Chloroflexi bacterium RBG_16_58_14 GN=A2W36_06660 PE=4 SV=1 +---MHLLLCTDGTPASAPATTFGAFLATSLRAKVTVLQAPAGHPWEHLAARAAEAvrdeLAEAGL-DCQVVSRSEFPRQAIVSQSAKGQYDIVVLGLLERGNWlRRWLRGPSTRRVLQQVATPVLVVPAD +>tr|A0A0R3TLP3|A0A0R3TLP3_HYMNN Uncharacterized protein OS=Hymenolepis nana PE=4 SV=1 +---RKVLFPLDKSSKVRAAIEWFFSFGYRQSDSIIFVNIVHPKYSRgvinlesssfnpsedfkldfdevhEIEDEYKEFARKAGVKFSTTCIADTDIAGELNMLADQEKADLIVTTALG----------ESIYDLIGDTKIPVLIVPS- +>tr|A0A0T9KF37|A0A0T9KF37_MYCTX Universal stress protein family protein OS=Mycobacterium tuberculosis GN=ERS075342_01446 PE=3 SV=1 +-RIARMTLAYRRRPDADGPLTAAAALAERLGAELRLLTLLIRPPGlaarfrapggvldrqlAQAEEDLRYAAGLLgRGTPVERRTAIGTDIAKTLGTVDMLHGEVLACLSGRDGPLRKVFLGESSGKILRAAPCPVLVLPHG +>tr|K9AEU4|K9AEU4_9MICO Uncharacterized protein OS=Brevibacterium casei S18 GN=C272_13528 PE=4 SV=1 +-KLKRITAAYSGSSTSADLILGAAMVSAESGIPFRIASFAPRSRVlsaasigrdveagivdewtRVVRRDTDRILCSIdeldiRPGETEVAIGTGPSWAAALTSIGWEDPEVMMLGSSGLGTLKRVSLGSHATRILQNSPVPVVVVPRR +>tr|A0A0B2B7V3|A0A0B2B7V3_9ACTN Uncharacterized protein OS=Mumia flava GN=LK11_47290 PE=4 SV=1 +-RVERLVLGLDAEPSDEGAVEGALALARWLGASIALVTFGVRRLPalpfgggrradaevfavwrEDVERVHAEAAERIaaaGVEVGEQVVAVADSWRRVAERFRWEEGDLLVLGSSHEGPVERVFLGSTAARIAGHVPVGVVALPRR +>tr|A0A142H9M0|A0A142H9M0_9BACT Uncharacterized protein OS=Hymenobacter sp. PAMC 26554 GN=A0257_23110 PE=4 SV=1 +-APRRILLAADREAFALAPAAlALRELLALPGTELFVAHVSGGVEDDAGCAAALRAVQDSGLVAglpipKLRGYNQDDYAEGVLDAVRDTQADLVVVFARQRSYLGELFHHSVTARLLADCPVPILVLPTT +>tr|A0A1G1T781|A0A1G1T781_9BACT Uncharacterized protein OS=Hymenobacter sp. CCM 8648 GN=BEN48_12345 PE=4 SV=1 +-PPRRVLIAADRESFALAPEAeVLRPLLALPGVEVVVAHISSGVEDDEGCALALRAVQASGLVEglpvpELRGYQHENYAQGVLAAALDTRADLVVVMARQRSYLSDLFHRSITAQLLQSCPVPVLVLPTA +>tr|A0A1G1TDA6|A0A1G1TDA6_9BACT Uncharacterized protein OS=Hymenobacter sp. CCM 8648 GN=BEN48_07855 PE=4 SV=1 +-VPRRLLLAVDGAPFDLHPLPdHVRQLLASPQATLDAVFIPDGKPARPDAITVLSTIRLDDAVPamplsRLHVHHAPDVAAGILAEAKRLRADMLVVVARQHSLVGSLFHSSITARLLEQSPIPVLALPAR +>tr|A0A1E4AFE0|A0A1E4AFE0_9RHIZ Uncharacterized protein OS=Devosia sp. SCN 66-27 GN=ABS47_13820 PE=3 SV=1 +---MKIVAFVDSSLYAHSVIDHTIWLALERRASVELVHIVSPNEVAasniapihpggavllerddtlnaklaelerqgrERLEQAHRALNQAGVNDVQVRLCEGHTAQTMVQATQ--SASIAIVGKRGEHaDLARLPLGANLERLVRGSKVPVLAVSRS +>tr|A0A1M3KL28|A0A1M3KL28_9RHIZ Uncharacterized protein OS=Devosia sp. 66-22 GN=BGO81_05390 PE=4 SV=1 +RPLASWLLAVGKDNEVSRGLDDLVQSRMLEALPGEVVHVGELTELiRSDLESIGLRLTHAGHR-VSITVLDGEPVRAVAERLATAESQLVVVGKFGRSRVLPMIFGDGVArDLTKVNQGPVLVL--- +>tr|A0A0S7ZP89|A0A0S7ZP89_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium SG8_11 GN=AMJ53_16945 PE=4 SV=1 +--MPGIICAVRGGPSSQPTIHRAITLAQEVGQPIHFLYVVNLDFLERtatsrthtitkelrqmgdfILLTVQAQAQSQGVV-ADGSIREGNVSEEIIHLCQETKADYIVLGSPEGDRednaFTQEHLNQFAQLIEDTSGAKAILVEGT +>tr|A0A1C2JD64|A0A1C2JD64_ACITH Universal stress protein OS=Acidithiobacillus thiooxidans GN=A6M23_18315 PE=4 SV=1 +MSDPVLLTAIDGSQNALLAAAVAARFSRLLGARLGLVTSLHVAKDplgfggglfsrdltdrllaearleaESNLRAVAERIEEHCDIgLPEYFLLEGDPEQEIPHLVQsLPETIMVVVGQRGFGTESKprglpHLLGGLGAKLSLALAVPVLLVPPD +>tr|A9AW06|A9AW06_HERA2 UspA domain protein OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_0596 PE=4 SV=1 +MKPFNLMIYLDGSSAARRMVAYLAPLARKSHVKTTFLVDEAHQDEAEMYFfNAEQLLQSDQAP--TRTIRGATPERAIVLETRASQPDLVAFGPLRKEGWRRWLGQSAIGSLARRLTCSMLLMQG- +>tr|A0A1H1UYQ3|A0A1H1UYQ3_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Gillisia sp. Hel1_33_143 GN=SAMN04487764_3031 PE=4 SV=1 +--MNKIVCATDFTRNSIAALQYAFKMSNLLKKELIVLNICNPEEDdeyhsasdnQAILDTRVQLLQEYCSihlkanfdsLQIRAIIKKGkNIPKKICNFIKDLDIAFLIMGTHGNSPFKAKNFGSITNAMIAASTFPILAIPPT +>tr|A0A1W9UJQ0|A0A1W9UJQ0_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium 4572_35.2 GN=B6I37_08745 PE=4 SV=1 +CPVSKVLIPVDGSAYALAAVHEAAALSSQLGtniASITLLRVVDiskhrektaelDQDADRILSEARQILLDAGIDeqKIVSRAHYGTPADSILALSVETDANLIMIGRRGRSASKELLMGSVSSAVLHRCGGSTVAIISS +>tr|A0A1G0ZW29|A0A1G0ZW29_9BACT Uncharacterized protein OS=Lentisphaerae bacterium RIFOXYC12_FULL_60_16 GN=A2498_01365 PE=4 SV=1 +RVFHRVWVPVAGGRNSAFAFEVATMLADPADGVIVVLNVRsGGeSITFDLEPFIDEQASRLNFPRERVVSRTvesRRVADTVVEEIERagDRCDLVVLGASPRSLFNPFTRESMPNLVARRCTKPMAIVNRV +>tr|A0A1Q7KHX9|A0A1Q7KHX9_9ARCH Uncharacterized protein OS=Thaumarchaeota archaeon 13_1_40CM_3_50_5 GN=AUJ08_00300 PE=4 SV=1 +VDKKNMVVVYDGREHSELVLKATS-------wlehsGRfkVNLLSISkGGGEKNSV-AMQQDFLSQLGVELKETqltASSSrsaDIVLSA--ISSF--QPDLVVMGATLGGFSVFnnPDFLALLDQ----LNCPVIIARGF +>tr|G2HBX5|G2HBX5_9DELT Uncharacterized protein OS=Desulfovibrio sp. A2 GN=DA2_3282 PE=4 SV=1 +---SNVLLCVDGSGENLRMADHVGfMLATPgaENHTVTLLHCREPEngagrgatgahgpvgphgladgplPGEEAIAAAREAVLANGVDesRVRVLMVRAsdrtgrtdrsDKAETILRVAEQDRFAVVAVGRRTalpDTLMRRMFGRSVSERLHDRVNRFSLWV--- +>tr|C0QL51|C0QL51_DESAH Putative universal stress protein UspA OS=Desulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2) GN=HRM2_10250 PE +---KNVLLYLDGSESCLRMADHVGfILSHENRHRLDILTCEKSSDITRAVEKCKSMLLDYGFPadLVRHKSVITdNVAGAILDGVNDEQYAAVALGRSGtkRNLLQRLFKGPVCSILFKELNETALWI--- +>tr|A0A1V0DC09|A0A1V0DC09_9BACT Uncharacterized protein OS=Rhodothermaceae bacterium RA GN=AWN76_004780 PE=3 SV=1 +RPIRRVLLACDGSAPSIQTMQRFAQLQPfGTDLTVDLVHIREDTGEAArhradlLLHRTRTYLEAHGFQTLNETSMEGdHTAERLLRHAEHHEADLIVAGAHSVSAVRRIAFGSTTHALLDQSTIPLFLYH-- +>tr|A0A024M608|A0A024M608_9MYCO Universal stress protein family protein OS=Mycobacterium farcinogenes GN=BN975_04534 PE=3 SV=1 +---MTILAAFSASRHSSAPLNLAVQLARTTGEQVIAAAVVERSWPprddpveseyvayvraqaTQALQRAVAVL--PVDLDVTSVVHEStSIPTGLIELADAHRVTLVTVGSSSSGMIGRVTLGSVTERLVHTARVPVAFAPRG +>tr|A0A0Q9DRF6|A0A0Q9DRF6_9MICO Uncharacterized protein OS=Microbacterium sp. Root280D1 GN=ASE34_04575 PE=4 SV=1 +---RGIVAGVKDDDLMTAIVGAAAGEARARQEPIELIHSSFSGVipatvetrATIAARVAAVESMVDAGTRVRTRYTQRPPAEALLDASR--NAALLVVGVGHPRG-AGHALGAVTHDVLVNIDAPVLVVRRS +>tr|A0A1V4QAC8|A0A1V4QAC8_9ACTN Universal stress protein UspA OS=Gordonia sp. i37 GN=B1964_07285 PE=4 SV=1 +MPSRKLLAAYLPTPGGEDALALGIALAGPFHAALDVCMVLPPPPQGgdggadpvrktteMLDAQAADWLSEAvgripDEVVAEGHIAFHeNAAEGLVAEAESTGSAAIIVGGSGGGIRGRHALGSVVNDLLHISTKPVVITPLG +>tr|A0A0C2N8E2|A0A0C2N8E2_THEKT Uncharacterized protein OS=Thelohanellus kitauei GN=RF11_01625 PE=4 SV=1 +---KKILFTVCEEPNSRQAFDYYATKIHERSNPIVLMNVVVPSFSFadgripplyhedkqsggvtqeklkkteDLLDGYLERCKELKLRctKETVILKHNKVSDEISSYAKG-KFDLIVMSGGKHSTFERIFLGSTTLNTIQKSSVPVMVIP-- +>tr|A0A0W0VR38|A0A0W0VR38_9GAMM Uncharacterized protein OS=Legionella londiniensis GN=Llon_0448 PE=4 SV=1 +QANARVAVAVDPNDEesegknlSLNLLEISHSLAKHFSGNLDIISCWHFPFEDylrdniwvkvpehelkkmiheekeRTMSQLKALMKEVNVSgeKHQIHLLKGKPEKQIPDFIDENKIDLLVMGTVARTGIKGFIIGNTAENILQELDCSLLALKPQ +>tr|E8RCR5|E8RCR5_DESPD UspA domain-containing protein OS=Desulfobulbus propionicus (strain ATCC 33891 / DSM 2032 / 1pr3) GN=Despr_1706 PE=4 SV=1 +RKEIRVAVAVNPGNRetaerdlSIRLLQHARSLADTCSGELDILSCWDFEFERylrgntrvdipedtmrntvqtaqtSHQAELNLVIEASGIGgSFEVHRLRGRAEKMIPFFVKSKHVDILVMGTVARTGIFGYLMGNTAENIMDELECALLALKPG +>tr|A0A1Z4VI32|A0A1Z4VI32_9CYAN UspA domain-containing protein OS=Raphidiopsis curvata NIES-932 GN=NIES932_26940 PE=3 SV=1 +KMIQKILLAVSGLGHAEEMMKNLKELPSIQSAKVTVLHVVPSQSTAaamtekweeggKILANAIQSLNFDPSQ-VSSILRQGDPKDVVCQVADEIGVDLIVMGSRGLKRLESILSNSVSQYVFQLSSRPMLLVKDD +>tr|A0A1F3RS21|A0A1F3RS21_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium GWA1_52_35 GN=A2X97_15735 PE=3 SV=1 +GKWSRLLYPTDFGKHSERVFTRVIALARILKAEIMVYHEARSPRNiqarrrtiefntavdsvpsawvdswvarRTRMQEYVDRARKSGVIaNAFLDVGGLPLHEAILRAARKLNARLIATASFS-GPVKSAISGAVTKRVVNNSHCPVWILHEK +>tr|E8T453|E8T453_THEA1 Uncharacterized protein OS=Thermovibrio ammonificans (strain DSM 15698 / JCM 12110 / HB-1) GN=Theam_1419 PE=4 SV=1 +MLFQKVLYPFDMRKSSLSVKPYILKLKEAGCKEVHMLYVLIPSDWgllprdeydceeklevlkgaldegygdavvriYRRMKEVAKEFEEAGI-SVRVVLVPGELDETIAEYAKKHNISLVTLGITSES-LSFFRVGR-LLDIIKEVQQPVLIVKA- +>tr|A0A1D2WLB6|A0A1D2WLB6_9EURY Uncharacterized protein OS=Methanobrevibacter sp. A27 GN=A9505_07740 PE=4 SV=1 +-MYKKILVPTDGSEASFKEVISASNLLAE-DGEIIVLSVAKQLkqhplqikkdikktneTFIEYAKENVEEMKKKfdSNIKVSTKVVVGFPAEAICDVAEKEGVELIVISSAGERGFSKRIIGSVAGKVCSISNINVLLISNE +>tr|A0A101VY77|A0A101VY77_9PROT Uncharacterized protein OS=Alphaproteobacteria bacterium BRH_c36 GN=APF80_03725 PE=4 SV=1 +----SIVVCFDGSEESHRALRYAVRIGSGTDADLTLLYVRPFDqglrtsgldlsvvrenilswgldlPGMRVLKEGRDALVELGWldseweqehahaqvrgdplgdnaivysspsgRSVVLRLLVAqSVADGVLDECELGQYNLCIVGWPASGGASgvGYITHEIATRIAREHTGTVLVSR-- +>tr|A0A1Q2M890|A0A1Q2M890_9GAMM Universal stress protein OS=Microbulbifer agarilyticus GN=Mag101_15435 PE=4 SV=1 +---KVVLATVNYQAqttqqrqLNRQITERASYIAEVYGAELHLVNAFLDSMLYPDRGALAKLASKTGVPTDRIHVKQGYTNEVVAEIAKEINAELVVMGTLNQYGETGSlLRGNTAERVIGSLDIDVMVCNA- +>tr|A0A0C2FBT6|A0A0C2FBT6_9ACTN Universal stress protein UspA OS=Streptomonospora alba GN=LP52_24045 PE=3 SV=1 +DSFRRAMVCLDHGARDDTGIALAQSWADQLKLELELVHVASTEDDveasEERTARIADRMADGGASVGHTQLRGSAPAEEVAKLLSRHPGSIAVLANRGRVGIARSILGSVSSRLLETSPAPLVLTRVP +>tr|A0A1W9HFZ8|A0A1W9HFZ8_9PROT Uncharacterized protein OS=Proteobacteria bacterium SG_bin7 GN=A4S09_05410 PE=3 SV=1 +-RFQNVIYPTDLSSHSQKTLNAFLPVAKLMNAKIHLLHGLQGSMtnAtlayeglsdvafnfytqemkrikksrEKQIGAWAKICKSHGVNtTTEIAEDQTQVLDTVLKVAKRKKANLIAMATTS-GPFENLMTGGITRQVVRYADIPVWIMH-- +>tr|A0A0C1LMH3|A0A0C1LMH3_9BACT Uncharacterized protein OS=Flavihumibacter solisilvae GN=OI18_01870 PE=3 SV=1 +--MANILVPFDFSVNATTALDQACLVAVKKRLSIEVLHIVNFKTASEypadwgvdphspdlhmirkklnehVDERKRTCSAVEV--PIEISVKESVMVnGGIINHMLHKKSDLIMMGTHGTTNAIERFWGTNSSTMINHSLFPVMVVPPQ +>tr|A0A1M7IXT7|A0A1M7IXT7_9GAMM Universal stress protein family protein OS=Rhodanobacter sp. OK091 GN=SAMN05428972_3627 PE=3 SV=1 +-SFEHVVIGCNGSIESIRAIHAALPFLRMAKHVTLVDGDVRSSndaDSCLPHFDPFVYLLRHRITAKPQYIRasSDLAGDILLKKARNAQVDLLVMGAYSRSPARERVFGGATRRVLEEADIPVLMQH-- +>tr|A0A1F8NKU9|A0A1F8NKU9_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_47_49 GN=A2Y53_00170 PE=4 SV=1 +-----LLICTDGSSGSILSADLVSKLKFPTNIQITVLGVSENKsdldNIVASMDLIDKKFG-TTYV-VDRRIRNGKPIEEIMSEVLESKYDLVVVGGGRGQLDLlHPQLGSTTSKLARKLHTHFLVARN- +>tr|U1NXK6|U1NXK6_9EURY Universal stress protein UspA related nucleotide-binding protein OS=halophilic archaeon J07HX64 GN=J07HX64_00610 PE=4 SV=1 +--FQRMLYATDFSANAEQPFE-AFRYLRHASEEATLVHVETPRDPgretgnsQERLTDLATQLEAWDI-ETRTDLRQGDPTEGILAAESEHNPTTTLIGSRGHSRLRRLLLGNVSEDVVAQATGDVVLVPPE +>tr|A0A075TTI2|A0A075TTI2_9CORY Uncharacterized protein OS=Corynebacterium atypicum GN=CATYP_10235 PE=4 SV=1 +----RILVSFRADSl-THDAVEIAAWLARTdfPPVRVRALSTFVRPWPatslkklggkyvdwfrreaRAAEKRVKAAFTDAGIPekfwddp-VAVFADGPSEHALITAAADKFGADIIAVESDDAAEKGRLKVSNTADALLHSSPRPVCLAPRK +>tr|F8E3G8|F8E3G8_CORRG Universal stress protein OS=Corynebacterium resistens (strain DSM 45100 / JCM 12819 / GTC 2026) GN=uspA3 PE=4 SV=1 +----RVLMAWRPQSTSDEAAEVAAWVGRTEEIRVRAATVIPRAWEiqpgaqefqeyrnwvmaetQACMNAALSALGKAGLPqgmlaeeDPAVVDIAPTETKVLIKAAEDFEADFLLLGSHPAAPRSRFRMGSTADALLHCAPLPVLLAPRS +>tr|K1YIB3|K1YIB3_9ZZZZ UspA protein (Fragment) OS=groundwater metagenome GN=ACD_73C00108G0001 PE=4 SV=1 +--IRKIFVPIDGSEGSLEALSIAMKLAHQMKAEVQPVSISEFAYVpslsyvdpksynqdllkrRKKEIDFCLKKMSVDDKVLPAIVKMGNAAHDLPLLVKKTKSDLVVMSTHSRKGLVFTLLGKVAAHMIHHSPSSVFL---- +>tr|U2FI96|U2FI96_9PROT Uncharacterized protein OS=Campylobacter concisus ATCC 51561 GN=ATCC51561_1301 PE=3 SV=1 +---DNILVSWTGTTQSSRALTGAIDLLKSAK-KVQCITSKASLGDNaeLNLKKLEEYFKVHNISaSFEVIATTTIPGEALLKAANDRNADLIVASRYGENGLMEMVLGGTSRFFLEHTNIPVYL---- +>tr|A0A1F8T8N3|A0A1F8T8N3_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_19FT_COMBO_62_14 GN=A2Z37_08365 PE=4 SV=1 +DQVRRILICTGAELPSMETLRVGGQLASHGSAELTLLHVMSQIALQpestadelfasaegamesgtregLHFKEAIRILRDMGV-TakITPRLRHGLVVDEILSELDEGDYDLLAIGAHRRpGLtrWLEVMLDDVAEQLMSHAPCSVLVVRPA +>tr|G8T6W2|G8T6W2_NIAKG Uncharacterized protein OS=Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10) GN=Niako_1596 PE=4 SV=1 +FVMSTVLVVTNFSDASHNALAYTCSLLQNTQAHLVLMNIYDFPGNMtgdaiaiaamseiiehdaALLEREFQWVQTNyPALQVDTEMVTGVFQEELQRKVIESNAVLVVMGAGG-NYTNLLSWDANIINSFIDLPVPMLVIPST +>tr|A0A0Q7VSJ2|A0A0Q7VSJ2_9BURK Universal stress protein OS=Duganella sp. Root1480D1 GN=ASD58_11425 PE=3 SV=1 +MGFKTVVVHVNSSAETERRVRLAAQIVRMSKGRLVGAAMSGISRLLyadhattmgvsmaaqcidearenarANLRRFETQCQMLDLPSFESRLLDDQAADGLVLQSR--YGDLVVLGQVNPDGPVSPLEEETPEYVAMNSARPVLVVPYA +>tr|A0A0Q6VVP8|A0A0Q6VVP8_9BURK Universal stress protein OS=Massilia sp. Root351 GN=ASD15_10515 PE=3 SV=1 +MTYRTILVHADLSRHAPQRIRFAATLARTFDAHLVGGAMTGVSRFLmpasiamggpmiaeqvdlmresaeRALAQFDTLADQTGAPSFERRLVRDEFDGGMALQAR--YADLVVLSQTDPDNPVPGDWNDLPEYVLLNAVRPVLLVPYA +>tr|A0A1F4JUA0|A0A1F4JUA0_9BURK Universal stress protein OS=Burkholderiales bacterium RIFCSPLOWO2_02_FULL_57_36 GN=A3I66_04740 PE=4 SV=1 +MSYKIILVHVDESRHAKARMEFAASMAMDADAHLIGGATTGMSREFiewigfdekaldldrlsdmlreraeQSLTQFEIIVRRTGVASFEKRLIEDDLSAGIAMQAR--FSDLVILTQSDPRDSASGVSGSFPETVVMESGAPALILPYV +>tr|A0A1E4ZYR7|A0A1E4ZYR7_9GAMM Uncharacterized protein OS=Chromatiales bacterium (ex Bugula neritina AB1) GN=AB833_13085 PE=3 SV=1 +MSYKAITTYIDDTPECEAWCEYAIDLALQHNARLVAVAARNLASHLiatdylalnsrwvselqeridknvsKIAALFERQCEKKGLTRAEVRVITGTPVDAMKHEAL--FSDLIVLGQYQKYQEqntngASLSRAGLQESLLMSSARPILYVPTQ +>tr|A0A1E3CYQ0|A0A1E3CYQ0_9RHOB Universal stress protein OS=Rhodobacter johrii GN=A9O63_04885 PE=3 SV=1 +MAYKSLLTVATSPERVEPAITVASRLALSGDAHLDVLALGIDGTQVayynmggtavvlqmaleraeqeaqAVEKAAAAALSAQPaMLRASVEsavAQMGGLAGLVALRSR--FADLVVQSRPYgKGRG--AESEAVVEAALFEGQAPVLVIPDD +>tr|A0A1E4NNL9|A0A1E4NNL9_9GAMM Uncharacterized protein OS=Rhodanobacter sp. SCN 66-43 GN=ABT18_04710 PE=3 SV=1 +--MKDILIHVRDFGKRTPAAHFGVRLAATLGASVTGVYACPRPLYIapaygpelmaeavnnarelvkdavQAKQSFLDWAASLGVSQSEWLVAEGPVGDALAQAAT--RHDLLVLDHAEDDRG---SAW-DIPGVILKTDVPCIVLPHH +>tr|A0A1Q4FA59|A0A1Q4FA59_9GAMM Uncharacterized protein OS=Xanthomonadales bacterium 63-13 GN=BGP25_04550 PE=4 SV=1 +MSEFDVVIHLRNCEIAGPAVEAGLALAKRLEAHVLGLHVVALSTAAfvspeavavqvnetshlleearARAPWWREELDRHGLQGEFQ-VVQGDAIDALCHASR--WSDLVITERPCANPD-APVGWGIASRTVFGSSAPVVVVPEG +>tr|T0RAW4|T0RAW4_9DELT Universal stress family protein OS=Bacteriovorax sp. Seq25_V GN=M900_1267 PE=4 SV=1 +--MEKAVIFATLETEVLEQLKKVKQHLDAEKSTVHIVHCHKIQMYInelsvftfpteneipqmteATNQVLEQFAKELGIKNYTVETLfDHDPKERCLNYLKDKNATLCVLGAKKKSGFETLFEGSFISYMNKFSPCDILTLRP- +>tr|A0A0W1SNR1|A0A0W1SNR1_9EURY Universal stress protein UspA OS=Haloferax sp. SB29 GN=AUR66_12555 PE=4 SV=1 +--FSRPLLPLANEDDAEVTCGVAFPRIAANDGTAFVVHVIEKAGGapdkagveqreevaDEVFDVAHRAADDVGV-DIDTELRFDtNVGDAILDAARDVDASAIVFTPRGGRSWWDLFSGDVRDRLIRKSDRPVVVLPHG +>tr|C7NMS5|C7NMS5_HALUD UspA domain protein OS=Halorhabdus utahensis (strain DSM 12940 / JCM 11049 / AX-2) GN=Huta_1212 PE=4 SV=1 +--FGRVVVPVASRDDAAATAAALAPYIDAPDRTVIAVHVIEKADGaldkasveqreadaEAMFGIVTEGLDGVDA-ALETEIRYGtDIAGTLVETADDVAASAIVFTPRGGSRWKQLLSGDVTHNLVHESDVPVVVLPDR +>tr|K7KAH2|K7KAH2_SOYBN Uncharacterized protein OS=Glycine max PE=4 SV=1 +FAGEKQNSTFQFLAssfrYGKGTNCWAVDNLINKGDQIILITVQPPQAHHTRKELFEDTssplvpleelrelnftkqyeIAGDPEAKAVAKVYWGDPREKLCNAVEDLHLDFLVVGSRGLGPIKRVLLGSVSNNVMTNASCPVTVVKGK +>tr|A0A0F6G8B0|A0A0F6G8B0_BURPE Universal stress family protein OS=Burkholderia pseudomallei MSHR2543 GN=BG16_3856 PE=4 SV=1 +-MYRHFLVPVDDTDAGIDTVAYALEFARSIGARITFVQTRIEFeaadaarrigeterkeqtqrtddagksgecgrsdesvrpaptpdaaarpaaeatpaarAPELPIAKAEAAARAQGV-PCDSVRAAGATtADALAGAMLAHDCDLLCVGPALGDAAAAPPH-ACVADRLAARGIAVLTCAFR +>tr|A0A095YLL3|A0A095YLL3_9CORY Uncharacterized protein OS=Corynebacterium tuscaniense DNF00037 GN=HMPREF2129_04810 PE=4 SV=1 +KGITRVNFAFLDTKEaarsSTRGIGLAAALALTLDVELRIMAFSPEEtynfdddlthrplvdEWNEASLALLDRAWDVVMNvaqdlnikdphaelknfEVETRVSAGEGWCTVVDSQQWKKGDLLFVDSSPQSKTrsGYVHVGPHTAEFLSYAPVPVIVLRG- +>tr|A0A0B6TQ15|A0A0B6TQ15_9CORY Universal stress protein OS=Corynebacterium marinum DSM 44953 GN=uspA PE=4 SV=1 +RGVTRVNYAFLESEIdeNDPSLHFAAQLADSWGVDLRVLAFSPSGladqpfhdkfdfsrelvdEWREHSLAVLDRSHDVIADlfpdlAVESEIGSGKGWQGAIDALKWKKGDLLVLGSTPPGTLERVFVGSTATDFLRHVHVPVLIHPA- +>tr|A0A1X7IW16|A0A1X7IW16_9CORY Nucleotide-binding universal stress protein, UspA family OS=Corynebacterium pollutisoli GN=SAMN06295981_0990 PE=4 SV=1 +RGVTRVSYAFLETEIdeNDPSLHYAADLADTWEVDMRILAFSPSGiadqafhdkldfsrelidEWREHSLAVLDRSHDVVAEqhpdlSVESDIGSGTGWAGAIDALKWRKGDLLVLASTPPGPLERVFVGSTATEFLRHVHMPVIIHPT- +>tr|A0A1V5BMI4|A0A1V5BMI4_9FIRM Stress response protein NhaX OS=Pelotomaculum sp. PtaU1.Bin035 GN=nhaX PE=3 SV=1 +-MFNKVLVVYDGSPEAKKALQDGLKLAKIAGAECHLVRVIKKPKHvsneafqqeaaseptlgQKELVGARFLASQAGF-DLPTHTILGDSCEVLKNFVQKGMYDLVVVTPKQDNTLKDVFFGGYVEKLLRNSDISVLVVK-- +>tr|A0A1L6I6B0|A0A1L6I6B0_9BURK Uncharacterized protein OS=Paraburkholderia sp. SOS3 GN=BTO02_28655 PE=4 SV=1 +-PPHRFFVASDDSDASRVSVDEVARLMQ-AGDALRVARVVLDPVGAPPVDTLDSVVLQAAGH--------GNLAHAIVGAALEWRADLLVLGTHAGEPSGKWRFASIAEQVAQLGALPLLMVP-- +>tr|F8C3X0|F8C3X0_THEGP UspA domain-containing protein OS=Thermodesulfobacterium geofontis (strain OPF15) GN=TOPB45_1619 PE=4 SV=1 +----HLLVCYDGTPSSTKIILYLKELFSNTPLELTLLKIISHPSasqgietdlykklqkeafleekakevflqAERELKEVSERLKEHLPAKIYTKVLfkYGDIAEGIINFSKENLFDAILVGRRGLSKIATYILGGVTHKLIVSSLIPVWLIRGD +>tr|A0A0U4N1Z4|A0A0U4N1Z4_9BACT Uncharacterized protein OS=Caldimicrobium thiodismutans GN=THC_0868 PE=4 SV=1 +----HFLLCYDECPACRNILTYLKHLFEGREIELSLLHVITIPTslllpqrdylreikreeeiekfcrenqerVRKRFEEIIQDLLKSLQVKAHFYIEfaESDRALALLQFLKDKNFDAVIAGKRGLGRLASIWAGSLTQKLILYTHQPLWIVRGK +>tr|N1WQ46|N1WQ46_9FLAO Universal stress protein OS=Psychroflexus gondwanensis ACAM 44 GN=pgond44_08827 PE=3 SV=1 +FPFKNIVFVSDFKEDISSVFEEVKKMAEKCHAKIHLLNINTTSDVnsvENGLQPIRDFLKDFSKpEDYAIHVYNEsSVLSGIEKFEESNEVDLIVMYTHSRKGLSSIFSNSIAESITNHSKKPVMTVH-- +>tr|K6VWB3|K6VWB3_9ACTN Putative major facilitator superfamily transporter OS=Gordonia rhizosphera NBRC 16068 GN=GORHZ_125_00830 PE=3 SV=1 +---SPVCFAYDGSDLADSAITRAAEYFD-YGRDAVVVCVWQPADVgfttgerhldpnnassvcgvaEQTAQRGADLAEKAGFRARGIAVEAAPTWRGILRAAAEHDASMIIIAPHRRTGILGHLQGSVAEAVAANASIPVLMMPSC +>tr|A0A1E7H2E5|A0A1E7H2E5_9DELT Uncharacterized protein OS=Desulfobacterales bacterium C00003106 GN=BA868_04670 PE=3 SV=1 +--FERILFTTDWSPTSLRALEYILGFKKLVK-ELDIVNVIYDKLTVRAIRELKKRLIEtrarclDEDIEAEYHLYAGETASEIILAAEEYDSTAIVMGLTHNQRFRDIFRGRPSCRVASRASLPTLIVP-- +>tr|A0A1F9AZN6|A0A1F9AZN6_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RBG_13_49_15 GN=A2V65_05540 PE=4 SV=1 +---SKIMASVDGSESSLKAVDHALYMIHSHpDAKLTLYHVKPMLkDYceidftktgettdnllemgdrrclADFYGHVRRKIKEYQMDEHRIEYvevdGKLSVGKTILSTAQHQGFGNLVIGRRGID--RSFYTGSVSNYIIKNGGdMAIWVVP-- +>tr|A0A076MWN7|A0A076MWN7_AMYME Universal stress protein family OS=Amycolatopsis methanolica 239 GN=AMETH_3063 PE=3 SV=1 +SAQDAIVAGIDGSDHSLRALRWAAANARRRHAPLHVVYAFAPLAGFygagmpvlqnaydelvraveRTLAEAVRTAREVAGDEVTITSEMPDEPAAPLLVSRSRGARMIVLGSSGAGGFTGMLAGSTTLGVSAHAHCSVVVVRG- +>tr|A0A1D2U069|A0A1D2U069_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium SCN 57-15 GN=ABS95_03165 PE=3 SV=1 +---RSILVPFDFSKTSVEILRGIVPFAKSTGASIHLLHVIEPSLSsddshgrlDDELADVSESMLKiwagrivRGEARTFASTRIGLVVDEVISRAASIGGDLIVVGADGYHSPRAITLRSAAERICRFAPCPTLIIPES +>tr|A0A1R4KR67|A0A1R4KR67_9SPHI Putative universal stress protein UspA OS=Sphingobacterium faecium PCAi_F2.5 GN=FM120_18125 PE=4 SV=1 +--METIIFLTDFSIAARHAFDQLLTIAKRTKINnVIIYHSLAYFNNkfyntgdfmlpppvidemeiedvKGKLRLLKQEFLTVsPVTEVSAHYDLLTVMDGVLRISENEKIDLIVVGLRGSDDGGKNSVGSTTVDLIESHAFNLLLVPE- +>tr|A0A1L9C479|A0A1L9C479_9EURY UspA domain protein OS=Methanohalophilus portucalensis FDF-1 GN=MPF_1138 PE=4 SV=1 +-KFSKVMVPLDFSDNSSKILDVLWQMTDVIH-EVVFVHIIENTKNKPQLEhkkkESFDKLYEIGNDlekklVVNYVVKEGKPAKVLDELAEEMGITLIMITTHGTESLKDILLGSTAENLLRNTVKPILLIPAD +>tr|A0A1L3Q365|A0A1L3Q365_9EURY Universal stress protein OS=Methanohalophilus halophilus GN=BHR79_07110 PE=4 SV=1 +-KFSKVMVPLDFSDNSNKILDMLRQMTDIIH-EVVLVHIIENAKNKTQLEnkkkESLEKLYEIGNDleknlVVNYVVKEGKPTKILDELAEEMDITLIMITTHGVESFKDILLGSTAENLLRSTAKPILLIPAD +>tr|B8KHM0|B8KHM0_9GAMM Putative universal stress protein OS=gamma proteobacterium NOR5-3 GN=NOR53_2249 PE=4 SV=1 +---------------AMTLAEAALGLAQTRGGNVHVVHAWLPYGAEllddadleltdserqvyrqqqrsdseQWFKRVVQRIESVADEplRVKAHLMESPAVPAVERMVKDTNAGLLVLGTVGTSANPGVLIGATTESILAGIGTPVLALKPP +>tr|A0A1F3RV15|A0A1F3RV15_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium GWA1_52_35 GN=A2X97_01365 PE=4 SV=1 +KCISKILWPVDPYELESaiqkSAAEALNGFLAASQAELEPVYILNPRQLDlgldapeqwleqyrpvaeGALKSFLEGrvvsSLSGNPWKFKVLVQASasnsAAVKTLNHHVNATGAEMIFLGTHGRKGMPRLFLGSFAETLLLESKIPVLVVNSK +>tr|A0A1F3Y6S1|A0A1F3Y6S1_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium RIFOXYD1_FULL_55_31 GN=A2603_16235 PE=4 SV=1 +QPIRKIVVAFEPSPESPenrlGS-ELATVFTS---------ELLAPDLKFvttvgkrdiepgetarqfaaKLIHS----LRQASAPIKSIEVIPTreglkDAVEALYDYAVRVNADLIIAPNHGRRGLSRLRRGSFVESLVMTSAIPVLTLGPR +>tr|A0A1V5S0R4|A0A1V5S0R4_9BACT Universal stress protein OS=Bacteroidetes bacterium ADurb.Bin302 GN=BWY47_01244 PE=3 SV=1 +-KRKYILVPFDYSDYSIKASLLAFDLANKFNIEIIFLHAYQDEESnvseaannAKDFYDKEIKAGRLPDAAYSFILRKGVPEDEIKRFIRRDEPLVIIMGTRGKDRKINDLIGSVTAEVMDISEAPVFAVPES +>tr|T0DI51|T0DI51_9PROT Universal stress family protein OS=Bacteriovorax sp. BAL6_X GN=M902_2855 PE=4 SV=1 +--MNKLMICVDITDESINAYKNQLKDFdWNRWDEVHLVHGFETQVYADtfyfasyplegqmgdieksvsdlLLGLSNEIVAEDYKGKVLGKCLfASSAKVALKEYAEENKIDEMIIETRGKHGIAALFSSSFAEYMVGHAPCRLMILRE- +>tr|A0A0S7YUR7|A0A0S7YUR7_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium SG8_13 GN=AMJ54_06330 PE=4 SV=1 +MAGKRLLLPQNFTPNDRKALDFVVdTFGQLEDVEVTLFHAYTPLPPvevshstvtdklrgnmsflqqqvqekEAGMEAIKAQLVEKGFAEASVRQvfrpRKKDIAGELLDLYGEKHFDCLVLNRKP-GKVSRFFTGSVSHKVL------------- +>tr|A0A1E4BB62|A0A1E4BB62_9BACT Uncharacterized protein OS=Gemmatimonadetes bacterium SCN 70-22 GN=ABS52_05570 PE=3 SV=1 +-LTGPIIVATDGTASASAAIKAAALMADRTGAHVTVLAVLEPLPLvaadyglllppaetdearrQALAQRVRDQLSETvgARPNWDVQVRDGDPAAVIARMGREAKARMIIAGIGHHDLLDRMFGGETALHTLRLSRVPVLAVPPG +>tr|K9SAA1|K9SAA1_9CYAN Transporter, CPA2 family OS=Geitlerinema sp. PCC 7407 GN=GEI7407_2607 PE=4 SV=1 +QHPFTIVVPVSNPNTQKNLIEMAALLAKQAQGRIVPLAIALGHTQspteeltsaftqgQNLVQRAVELSREHGI-EAQPLVRiDNNVAQGVSLASLEQDAQLIVMGWGDQTSLRTWLFGNMIDNVLWASHCTVAVTR-- +>tr|Q4C0C2|Q4C0C2_CROWT UspA:Sodium/hydrogen exchanger OS=Crocosphaera watsonii WH 8501 GN=CwatDRAFT_2422 PE=4 SV=1 +NDHFTVLIPIYNPYTQRDLIEMGALLAKKESGIIVPVSIAAAHVHmddpqvdgnlkqsQILLDRAIEISQEFEV-SAQPIIRiDDDAAQGISRSAKEKNANLIIMGWSENTGLKARLFGTILDTVFWSSHCPVAVMR-- +>tr|A0A0W0ZCF7|A0A0W0ZCF7_9GAMM Na(+)/H(+) antiporter OS=Legionella steelei GN=Lste_3088 PE=4 SV=1 +PLFKRIITPVERNDFPDNVISFSARLARYGNGKLFILNIAeNEREIqekrerlr-------AGPMKDPDT-DIELINQiEKNISKIILNEVIESETSFIIMNWSLEEHKRGRIFSSNIDHVMWTSTVPVAAAL-- +>tr|A0A1D2U069|A0A1D2U069_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium SCN 57-15 GN=ABS95_03165 PE=3 SV=1 +SKWKHVLMPLDFSPASSLALKYAAAITIENRADLTVVHSARNWAGLPTHDRSLLSMREARRqqvqqwirgelnfqLPCKVTVRLGSSSlASILSEANQERSDLVVLPTRAGQWLQRFRMDSVTEGVLRHSPCPILSIQEN +>tr|W2UDX1|W2UDX1_9GAMM Universal stress protein E OS=Gammaproteobacteria bacterium MOLA455 GN=uspE_2 PE=4 SV=1 +--MKNMLVVLDGSSSDEHVLRQAIQLAATSGGNIHLFMTVYDSIEElnryvgfdnyqevkqAILDEAEVKLRRLTDkfgDHFTSTMHWGrRWHFHVISEAKKISADLVIKAVQRHSRIAEFLHTPEDWHLLRGASCPVWLVNDS +>tr|A0A1Y5FY46|A0A1Y5FY46_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium 50_400_T64 GN=A9Q88_07905 PE=4 SV=1 +--MENILAVITHWDDAEAVLGEAEKLAARLHTGLEVLVPVHDQLGElskylnwqdfsqlqgEIVAAERTRLESLCAdKDYRLHVEWTtKVHATIVEKAQNYGAGLIVMMASHDPLLSVLIHTPDDWHLFRDTPCPVLAMVKD +>tr|A0A081T746|A0A081T746_9SPHN Universal stress protein UspA OS=Sphingobium lucknowense F2 GN=AL00_01970 PE=3 SV=1 +-SFSRAVLGWKLGPEATRALHALIALVE-PAAAIDVVTAGMTLPEctreLGAHHEVRRHLTRHGLTaDSHWLVDDEHiEAQTLTEHAQKIGADLLAVGGFSHSKMRDIVLGSVTRDLVERSDLPTLIVG-- +>tr|A3TKL9|A3TKL9_9MICO Uncharacterized protein OS=Janibacter sp. HTCC2649 GN=JNB_02110 PE=3 SV=1 +-----VVVGCDGSWDSFRAVDLAAREALGHGCRLTVLVVPRDDPPGsdePLSGYSA--AEDRGRsraqvtahlareralaaapdLGVDIV-VDAVDGPAVEALAQ--RAMMLVLGGRGRGGQRALSLSSPSDELVRHLRVPILIPGVR +>tr|K7YYK8|K7YYK8_BDEBC Universal stress protein OS=Bdellovibrio bacteriovorus str. Tiberius GN=Bdt_3123 PE=3 SV=1 +KKDLRIAIVTDLTKKCRASETYGVSLAKRLGAHVVLYHSVAETlrtveqymfaageatpsidtiyadikkDAQNSMEKKLERLRSKGI-SCEGFIEQEKTPlvDTFLAGPAG-HCDLICMGDESYGGLLGTLLGSNLRDMIAKSPVPVIVVR-- +>tr|A0A1V6C181|A0A1V6C181_9BACT Sensor protein KdpD OS=bacterium ADurb.Bin132 GN=kdpD PE=4 SV=1 +---PRLLVCVSPSPTSARLIRLAKQLAPGIDAEWYAIHVEERNAPdltsdaSETLASNLGLAEKLGGE--VVTTVGSNIADEVIRFAREKNIIIILIGYGPRQKFS-FNRKNLVNEVVRKSGnIHILVVTDS +>tr|A0A1W2G5L6|A0A1W2G5L6_9BACT Nucleotide-binding universal stress protein, UspA family OS=Reichenbachiella faecimaris GN=SAMN04488029_0298 PE=3 SV=1 +MKINTILVPMDYSPCAKNAFETALILAKKAQANIQVVSVSHMPHIhaevvgaasiiqpllqeyhEQLDQQFEELISSSNIEEVSVTNTkyNAPLHDAIYSCTIQNECDLIVTGTKSQQDWLTQLVGSNSMDMVERAKIPVLVIPE- +>tr|A0A0D2UED4|A0A0D2UED4_9PROT Uncharacterized protein OS=Skermanella aerolata KACC 11604 GN=N826_30575 PE=4 SV=1 +---EHVAVLWDGRRDTALAVRGAVSVLAIARQVTVLAAPERgsPDILRPAPFSIQDYLSGHGIQAELKRLDPEatLGFGAVLDSVVGHGADLLVAGAPEHALVPVHLGRPNRLDLLHRSPVPVLLAH-- +>tr|A4RXV5|A4RXV5_OSTLU Uncharacterized protein OS=Ostreococcus lucimarinus (strain CCE9901) GN=OSTLU_31831 PE=4 SV=1 +---FgcgrSICIAVDGAH-VKSLVHYVMREIMRKTDIVQIVHCAADENAStlarvsaeleEIREELKTFL-DDENQLDSVLLDfTGDIREKVLEHVDERmsSkaIDLLVIGNRTRRAvLSRNIIGSTAQYILQYAHVPVLMVPDA +>tr|A0A1M3PL91|A0A1M3PL91_9SPHN Uncharacterized protein OS=Sphingobium sp. 66-54 GN=BGP16_17465 PE=3 SV=1 +-SYRRIVVPLDGSCWAESVLPMAARLAKAADAELLLAHVVPNPELTEirplepedlllrqhvverneatargYLARIRTNLEAMGLRARVCSTRGDDVRSALAQLIQSEAADLVVLSARGQGANhhHQMRYGSVASFLMAHCTVPMLILQSE +>tr|A0A0A1YLA9|A0A0A1YLA9_9PSED Universal stress protein UspA OS=Pseudomonas taeanensis MS-3 GN=TMS3_0113365 PE=4 SV=1 +KTIHRTLVVIDPLQSEAQILERAKSIADLTQSHLHLLTCNKKSDLSSHLLDMQEALIDQGFSVSAQQAWNGNPHKTIIAVQQEQGCSLVIKQHQPDNPLTKSFLSPDDWALLRYCPCPILIVKAA +>tr|J8UWZ9|J8UWZ9_PSEPU UspA domain-containing protein OS=Pseudomonas putida S11 GN=PPS11_22539 PE=4 SV=1 +---------MAQHQHDDLALTKAKQIADLTHAHLHLLLCAKPNGHSSYLKLMQEQLVQEGYDVSAQQAWHDNPCKTVFAVQQAEGCDLVIKQHRADSALKKGATHS------------------- +>tr|A0A1R1LLF4|A0A1R1LLF4_9GAMM Uncharacterized protein OS=Motiliproteus sp. MSK22-1 GN=BGP75_20880 PE=4 SV=1 +PFNNRLLIVLRAGHKEQPALNRGCLIASRLGAQIHLIADERprHQKHKDWLQSYVDQLTAEGFQAQEAVWGKGDLIDNVLAAVRKEAHGLVIKYSDRSRPLAEALYTPRDWKLLRYVSCPVLIVRQQ +>tr|A0A1V5RJD3|A0A1V5RJD3_9CHLR Universal stress protein E OS=Chloroflexi bacterium ADurb.Bin325 GN=uspE PE=4 SV=1 +MSGARYLVIVDPAATGHPAFDRALLAARDSRGHIHLFGFSShpPlaangesssdaqeryrSEALATLGELAAHAEAQGIGVSMELGSSADVRQEMVQAAARSRADMVFKYSSE---RTLAHRDPGDWLLMRLAPCPVLMVKNV +>tr|A0A0F7ST98|A0A0F7ST98_PHARH UspA OS=Phaffia rhodozyma PE=4 SV=1 +SgedEGMKIVLGYDTTVDALLAFNHVLNRmSLHPNDHVYMAQVLPLTSAsassslfsspqstpnthtaqavsyegahgdeddtnlstlsskdrelvilRRIRKATMEKLTTEGIKllskgcKVTPVIvHSEQPAKALCTLAERHDADLIVIGRRKLSKLHRvVGAGSVGNYCLLHGGCNVLIVQ-- +>tr|A0A0M2Z6R0|A0A0M2Z6R0_9ACTN MFS transporter OS=Streptomyces sp. MUSC119T GN=AAW13_12710 PE=4 SV=1 +-GAGPVVVAVGNHGRAAAIVDAAARLARDTGSPLEVVHVQRTAVVEEqaadtesatearaAVTAHLDRLAAQGFAatgqVLDSVGDHAAAGRVLARHATEVHARAVAVGRSPRGPLAQFADGSLTTALARAASCTVVLVDPA +>tr|A0A0Q9S1K4|A0A0Q9S1K4_9ACTN MFS transporter OS=Nocardioides sp. Soil796 GN=ASH02_24720 PE=4 SV=1 +-QHRPVVIAIAAAEDARDLVAAAAELARMTGSPIELVHVHETTIVEEfaidaadwgwerqALRRHIDWLTQHGSTasglLLHSVGDHAAAGRVLARHANNVDARTVAIGNSPHGAAVQFAEGSLTHALIASARCPVVHLRPG +>tr|A0A0M9ZRJ6|A0A0M9ZRJ6_9ACTN MFS transporter OS=Streptomyces sp. AS58 GN=ADL00_08675 PE=4 SV=1 +-GPPPVIVAVGAHEGAAAIVDAAALLAEDSDSPLEVVHVRRTAVVEEqavdteteeraraAVTAHLDRLAAHGIAatgqILTSVGDHAAAGRVLARHAADVRARTVAIGRSPRGAVVQFADGSLTTALTHAAECTVVLVAPD +>tr|A0A066ZYG0|A0A066ZYG0_HYDMR Uncharacterized protein OS=Hydrogenovibrio marinus GN=EI16_03585 PE=4 SV=1 +-KGKEKLLLVIFDKAEESLLDRAVEQAKSRKLFVHVAYIHTYDVFDEdiaepesyeasekLLKKALCHFEDKGVYaegeVVESS--KVRLYDSLEAILHKVQPGYLMLPKGMKDKVKTLA--------STRGGQSPFLVIQ- +>tr|A0A1H6DQV2|A0A1H6DQV2_9GAMM Predicted arabinose efflux permease, MFS family OS=Marinobacterium lutimaris GN=SAMN05444390_108111 PE=4 SV=1 +-HKDELIVALAGDSTDNAVLERAIQVATQSRQPVRVLHVRTFEALAEgaldteslarseqLVSTARARLEQAGLSvsveVLEAA--AVHLTTRILEQIERLKPAGVILGRGPERTLAHILHGSLVDGLNRRAGEDIELMVVP +>tr|A0A0G3EIP4|A0A0G3EIP4_9BACT Putative amino acid permease YhdG OS=Verrucomicrobia bacterium L21-Fru-AB GN=yhdG_1 PE=4 SV=1 +----RIMLSVANPDNVLPLMRNTYRICQAREARVELIHMIPVSDYvplrdvPNFADEGREGIVEAmlyltQIFPVGTTIRYCrNIARGLVSAVRQHRADMLIMGWHGRPRRRLFSFGRTIDPVIERSPSRVVVMKN- +>tr|A0A1Q7KHX9|A0A1Q7KHX9_9ARCH Uncharacterized protein OS=Thaumarchaeota archaeon 13_1_40CM_3_50_5 GN=AUJ08_00300 PE=4 SV=1 +----RILIPYTPE-NPDRLIKYAIRIAKETAGEVNILRVITVPHQtplsagVAFADTAKRSFEPLekmldsETVPNHYLVRVShDTTEAILATIEEQKIDLLVTDFETLRHDKKLLTLTTCKVLAINAEDDALQLEP- +>tr|W1KYL5|W1KYL5_9SPHN Uncharacterized protein OS=Sphingobium chinhatense IP26 GN=M527_15240 PE=4 SV=1 +VMGGTIAVAWDGGREASRALRRSVPLLKQA-DRVILVMVPHGMGRSCDGVRAIRYLKDQGIRaDTQVVHTPGDASSAIVDAVTKMDANILVAGAFGHPRLHRFIFGGTTQYLLESKRRPPLFLSH- +>tr|A0A1V5IQR1|A0A1V5IQR1_9ACTN Putative amino acid permease YhdG OS=Actinobacteria bacterium ADurb.BinA094 GN=yhdG PE=4 SV=1 +--RARIMMtaavPTEprpapGDHAapggpaapggraAPagpaasggekpadsvRRRVEALPFGRRFASWQPRRGVGDEEEGeg-----------PGSGV-----------------CGPSEGGHD---------PAR-------------------------- +>tr|W5XW21|W5XW21_9CORY Universal stress protein OS=Corynebacterium casei LMG S-19264 GN=CCASEI_13035 PE=3 SV=1 +NNAQTMLIAYDGSDRAVRAMEYAARFL--QPGTVEILTAWEPVARQaarvvtrtglqqaamepeaveddpayeealAICREGVKVAEDLGLAgRAHLVESATTIASAIVDAADELDVDIIVTGTRALKGFRGWWNNSTAEHIVRHAGRPVFIVPPE +>tr|A0A0C1IAC0|A0A0C1IAC0_9BACT Uncharacterized protein OS=Flavihumibacter sp. ZG627 GN=HY58_08030 PE=4 SV=1 +--LKQILVVIDFSDTSRSVIENIIPIANEMDCDVHLLHIVKPsilpvlvnsqftiatrghyvaessNTLMQWQTSFISQVKKGRY--LFTHCVQGNEEKQIREYALRHHIDLVVLTHHRPYPWSKLLTRINIDRLAGRVQCPVLNMPDP +>tr|A0A162NMY5|A0A162NMY5_9BACT Uncharacterized protein OS=Flavihumibacter sp. CACIAM 22H1 GN=A1D16_05125 PE=4 SV=1 +--LKQILVVVDFSGKSRQILESIIPMANELKCDIHLLYISQPsvlpftinaqqviavksdqvawatSRMMALQGEFIHLMDKGRF--IYSHVAEGSMERTIRTFTMKHEIDLTILTYRRRFAWSKWLNRININRLTKKIQCPILNIPES +>tr|A0A0P7XUF8|A0A0P7XUF8_9SPHN Universal stress protein family protein OS=Porphyrobacter sp. HL-46 GN=HLUCCX21_07585 PE=3 SV=1 +-MYRSLLIALDTQDEagARLMAARCATRLVSPECAVHLAYVRTPLPRSyrrempknweaNERAEAEQWLRNFaehaeiSASVAGIHSPVGSVAQEVTRLAAALGIEAICVTAHRM-DPGRFLLGTNTQAIVRDALCDVIVVRD- +>tr|B9XRL9|B9XRL9_PEDPL UspA domain protein OS=Pedosphaera parvula (strain Ellin514) GN=Cflav_PD0421 PE=4 SV=1 +-----VLLPFDESPENDETVTLGISMAREMHAQLLLLHAVLLNLSpygpinlrkieaalcEEVIAQAEKTMLSAQEQGVSAIfaLEEGAPAAVINRAAARWQPDLIVMSAHQHDHFlSQIFRRRTIDKVIRHVKCPVLVLQTN +>tr|A0A1M5YCF2|A0A1M5YCF2_9DELT Nucleotide-binding universal stress protein, UspA family OS=Desulfofustis glycolicus DSM 9705 GN=SAMN02745124_03851 PE=4 SV=1 +DGNRKVLIAVNGSDDSMTAVRYISESLPKRGSELTLYQVMSAIPEEfwdlerdpvwikkvevirsweveqkrrssAFMEQARAVFETSGFPadavSFKIGEQKEGIARDLISECKN-NYDVLVIGRGESAHDTNMPLGGVTSKLLANVSsTSVWMM--- +>tr|S7TE90|S7TE90_9DELT UspA domain-containing protein OS=Desulfovibrio alkalitolerans DSM 16529 GN=dsat_2374 PE=4 SV=1 +--FSRILAATDFSRESDHAVRYAAELAEGLEAKLRILHVVESPRPltDEAVGDIRRTLAAHYAKDVAgrpfeaFDVSSGEPRQTIVEHALDTEADLIVMAHRRAeNSVFEPEADSVLAYVSQNAACPTLSLNRS +>tr|A0A1V4AVS7|A0A1V4AVS7_9BACT Uncharacterized protein OS=Candidatus Brocadia caroliniensis GN=AYP45_04460 PE=3 SV=1 +---GKVVIAVDGSAASVAGFTSAIHFAKSFNLKLIAVSVFDPHYhrvafesianvlsqeagqifrfkeqetlheeiidkglakiYQNHLDTVSRMAGDAGV-ELDTILMDGKPYDKILRFLQKENPSTLILGRTGVHNTNGLDIGSTTENLLRLAPCNVLLAGGS +>tr|E1R5P3|E1R5P3_SPISS UspA domain protein OS=Spirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228) GN=Spirs_1531 PE=3 SV=1 +-AIERILFPYDRSRSAENALRYYINNFHETTDQLIMMTASEGNSEYDSYEQERRFLEEHGV-TPKMLFTEGSPVHEVLAAAKREKSDMIMIGSHGRNKIV------------------------- +>tr|A8V474|A8V474_9AQUI Uncharacterized protein (Fragment) OS=Hydrogenivirga sp. 128-5-R1-1 GN=HG1285_10310 PE=3 SV=1 +-EIKNVVLFFDGREKSIHAVNYLNGLYKDLGLNSVKIvSVleedsvEMKNHIKDLLNTHAQFKYEAQF-F-------------------------------------------------------------- +>tr|A0A0G3EBC2|A0A0G3EBC2_9BACT Universal stress protein family protein OS=Kiritimatiella glycovorans GN=L21SP4_00519 PE=4 SV=1 +-RLEHILCAVDFSRESERAFRTAWKLARRSGAELSCYHLYDTTRSYypfasfrepagsrrrrkrrfrSFLARFDLQKKTIPCTFEQQRDARENEAERLLRDAENKACDLVMVGAKGRPASVTSLLGNVTENLRRTDLnVPVMILPHV +>tr|A0A0D3HVJ0|A0A0D3HVJ0_9ORYZ Uncharacterized protein OS=Oryza barthii PE=4 SV=1 +---MTMVVGVDESEHSYYALQWTLRHFfataaggQPPQYRLVVVNAKPTAASAvglagpgaadvlpfveadlkkssmRVIEKARELCAQ--VSDALFEVLEGDARNVLCESVERHQAEMLVVGSHGYGAIKRHLQHDGMDLARMyilpplgswieksvtpagSPLCSSIYCT-- +>tr|A0A0B5H133|A0A0B5H133_9EURY Uncharacterized protein OS=Haloarcula sp. CBA1115 GN=SG26_17500 PE=4 SV=1 +SGISSVLVPIAEGTHSALGVVVGGALAMGADAPVDLFHVSETKDetavarASTLFETARSRLP-EAVTVDTWHLEAPDVAEAIINESA--HYNVTVMGKPTQSRLREFVTGSVTAAVTDESENAVLTVQRD +>tr|W7STA3|W7STA3_9PSEU Uncharacterized protein OS=Kutzneria sp. 744 GN=KUTG_02438 PE=3 SV=1 +-ENRCVTAMVSGGVDDETVVAHAAAMATSHHSRMEVVHAEPPTAMDDCVFAEKVRIATLRLR-TTVTTVRTLPHEVIANSD---GSDLIVLGRGQSA-GRPSNPGVVTKTALHHAPCPVLVVHPA +>tr|A0A0Q4BAC1|A0A0Q4BAC1_9BACE Uncharacterized protein OS=Candidatus Bacteroides periocalifornicus GN=AL399_00660 PE=3 SV=1 +-LFQHLVLPMGARPEEMTKLQWVVSRTAGFHTHVHVLAEYYPDKGLtnklsSNLAFMKRLFDGQGIAyTVEQASKSGSFKVQLQEYAQKVGADLFMIVIYQSTTGIMPVLNTMDQEMIANSLnIPVLCLNP- +>tr|A0A1F3NHW3|A0A1F3NHW3_9BACT Uncharacterized protein OS=Bacteroidetes bacterium RBG_13_42_15 GN=A2Y71_14810 PE=4 SV=1 +-VFRNIIVPITYRREVKECISWAHFCSRMFNTKFILVRAKYTDANFkrgveSNTYFLSKYFTTKNVRfEIKVADGENNFGDEIINHARQVEADAILVMTTRDIGFADYVLGPQEQYIIANIEkIPVICINP- +>tr|A0A1F3CYV6|A0A1F3CYV6_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWA2_32_17 GN=A2X08_08170 PE=4 SV=1 +-KIVDIVVPFDIEEKSRIQLNWVVLLSKYFDSNINILKPFISNNFKnekmkKNMCFIRQILDEKNIVfGIRTSKRETKFNNAIYEFANEINADTIFIMSYQ---FKEFILKASK-----FGMkVPVLCINP- +>tr|A0A1J5BE82|A0A1J5BE82_9BACT Uncharacterized protein OS=Bacteroidetes bacterium CG2_30_32_10 GN=AUJ97_01515 PE=3 SV=1 +-GYEKFVVPIDITANSIQKIKWAVRLALHFNSTIHLIYVDTK-IKYhqqiyKNVALVKELFEKKNINyIEKKVICtKNEFVNEVLTYSDQINADLLLIINEANKLVPSFMKVSAIEKIIFNIYkIPVMCIIP- +>tr|A0A1V6I757|A0A1V6I757_9BACT Universal stress protein family protein OS=Bacteroidetes bacterium ADurb.Bin028 GN=BWX59_00601 PE=4 SV=1 +-EYDRILIPIDQDNTARIKIQWIRYINTLFKSKVYMITYNVSDSYGqknisSNIRFAENLFEKELIDyEIEVLESSRNFADSIFTYANEVESDLIMLMSDKYRSYVK---QIKKAENLELYKkIPIMCVNK- +>tr|Q3Z8N3|Q3Z8N3_DEHM1 Universal stress protein family OS=Dehalococcoides mccartyi (strain ATCC BAA-2266 / KCTC 15142 / 195) GN=DET0674 PE=3 SV=1 +--FGNILLPLDGSLFSEACLKQVSVLARDFKSKLTLLVVIQPPcipsdrspsiqpswdeyyqalleelkqQAQAYLERLTGELRENGIETEFRMEVSDNIPETILSTAEDINASLISFTTHNRSGIEKWYYGSVAAGLIENSPRPMLLWRNS +>tr|M0PHV5|M0PHV5_9EURY UspA domain protein OS=Halorubrum kocurii JCM 14978 GN=C468_02345 PE=4 SV=1 +ERVESVLVALRGTVGVGRNTRLVTGLFADAGVDVTLYHALDegetRDDGESFLNGVKTDLVERGIAAdriETLVEDADASIDAIAGHGE--AHDVVVMGETD-PSVTTFVFGMPSEQVAERFLGPVLVVQRE +>tr|A0A1I3CWU3|A0A1I3CWU3_9EURY Uncharacterized protein OS=Halorubrum aquaticum GN=SAMN04488066_1337 PE=4 SV=1 +EGIDRILVPIPAVAEFSRLPAFVNVLCEDSTREVTLFHVAEgdegRARAESIVAETREGMIEAGLDAelvDTRVVEGEEHDEEILRLAD--EYDAVVMYQAE-SRLGDRIFGTLPDRIADRTGDPVIVVRRD +>tr|A0A238WGM9|A0A238WGM9_HALVU Uncharacterized protein OS=Halorubrum vacuolatum GN=SAMN06264855_10769 PE=4 SV=1 +PPpsgTTRGIVLVKPDADLERMVTTLGTLFGETGVELRLFHAVEdqderlSDSTEYMLRGMVDHLAALGIDRerlTWDQSTDRDRLDVILSEAA--EYDFIVLSETQ-PNLRERVFGTVQSQLATTTGKPLLTVRAR +>tr|A0A1Y3GI80|A0A1Y3GI80_9EURY Nucleotide-binding protein UspA family OS=Methanonatronarchaeum thermophilum GN=AMET1_0797 PE=4 SV=1 +PPQKNILLVYRYIENLEKAGALINQFGLGGSE-IGLMLV---EPDETTLDQGVSKLMKQGVKLeniKERIETDREDIVNEIENRsA--DYGLLMIGRVD-RDLKDLILGDISKKIKEATYGPVILIEGM +>tr|A0A0S9NMI1|A0A0S9NMI1_9CAUL Uncharacterized protein OS=Brevundimonas sp. Leaf280 GN=ASF31_04675 PE=4 SV=1 +MAIKSLLVSASGDPGRDARRNLACDLASAFDAHILGIGASALVSlpidpygvnamsgqlqqlyremAETDIRTSKARFSEivgRRAPQSIWLQAIDNPATVINTAAK--AADLVLVAAHG---VGAPSRAPRAVDVVTGCGRPVLVVPKT +>tr|A0A170PSA4|A0A170PSA4_9ZZZZ Universal stress protein UspA and related nucleotide-binding proteins OS=hydrothermal vent metagenome GN=MGWOODY_XGa1796 PE=4 S +IRHYTILLPFNNAQPTATVLDAARQMAGPQ-GYVEGAFC-R-QMlpiiagegitlpgdylaefeeeGRQQAEAGRLKYLElleakdiplgdleASGLRAGWTEMVGSGPEGIGEYAR--LFDLVILGRSIGDSA--VDWKTTAEAVMFDSGRPLLIVSDE +>tr|C3KMY4|C3KMY4_SINFN UspA-like protein OS=Sinorhizobium fredii (strain NBRC 101917 / NGR234) GN=NGR_b00860 PE=3 SV=1 +-MIKVVLVRLDGTSGDEFRLAASESLAKLFDSHLVGLILNTLPEpalaesgvsvefwtrllqqaRERGKELESDLRSRlraisPSAELRRFDVYAHEQARVASRESR--AADVFLALRLSDADK-TVELHDVVEEILFESGRHLFLVADQ +>tr|A0A126RLI2|A0A126RLI2_9SPHN Universal stress protein family protein OS=Sphingobium sp. TKS GN=K426_09755 PE=4 SV=1 +MSYARLMVHLELGKSNAALLTVAGDLAERSHASLVGIAAAQPLVatpyagafisgeaieldraeIEREAKVAQSEFQTilsGRVADLEWRCMETTalLSDYLASEAR--SVDVIVTAPDRGGGLLPDTRRTSVGDLVMRAGRPVIIVPTH +>tr|A0A090GE88|A0A090GE88_9RHIZ UspA domain-containing protein OS=Mesorhizobium sp. ORS3359 GN=MPLA_1360076 PE=4 SV=1 +MSYKSILLSLNIDGPIEPITRIGVNLAKRFDARLIGFCAADAPLpvtmapegaaiaadvweqsrdeIRRRLTSLNGEFDGlva-GAVKTDWHGDIENPNHAVARRAR--MADIVVTSASQGASTGDSYRTVDPGSLVLRAGRPVLVAAQG +>tr|A0A0Q6YXS6|A0A0Q6YXS6_9BRAD Uncharacterized protein OS=Afipia sp. Root123D2 GN=ASC80_10400 PE=4 SV=1 +MAYKSIMVFLGLEQVNEAALRVSCDLADRFDSRIIGVTSGVPYVpvhlngmvaasmleadydeLALATARCESRFRDaikPCGQPFVWRESTEMPADFLAAEAC--SADVVIAELSENSPLMSGQRWLDFGDALMKAGRPFIIVPPR +>tr|A0A160UVI7|A0A160UVI7_9BRAD Universal stress protein family tandem domain CDS OS=Bradyrhizobium sp. G22 GN=BN2626_G22_4168 PE=4 SV=1 +MFFANVMVYVDPEQQEEGQIAVAESIARGFGASILGISAVAIEPpfvaegviieqttaedlerIRARLSAKEAWFRRivrLPSEKVEWRSAIAFPTEFLVEQAR--AADLIVVKRKQ--LWTNHPRYLDSAGAMLRMGRPTLSVPDG +>tr|N0B1I5|N0B1I5_9RHIZ UspA domain-containing protein OS=Hyphomicrobium denitrificans 1NES1 GN=HYPDE_25668 PE=4 SV=1 +------MLSLNDEPRVPNLVSAALSL-MGDNAHIIGLYAMPAV-vppqeiigagdrswldeqlraFEEQAGRVKNKFEGlfkDRPATHEWRFDnssfDATVADSVIEHGR--AADLIVTSRASRNGW----IDDVAERAAIESGRPVIVLPEE +>tr|B4RIM5|B4RIM5_PHEZH Universal stress protein UspA OS=Phenylobacterium zucineum (strain HLK1) GN=PHZ_p0257 PE=4 SV=1 +MTYADIVVDATPSPTVRQTLEVAAEFAEAYGGSLSV--------aafawprastlneallgnaggsalqalaFGEVLESTQAIHGEvfaDRQVVTDWCSGISDPNLILNEHLL--TADLAILGA--SASG--QFARVDATALAAHSGAPVLQIGSR +>tr|A0A1F8ID86|A0A1F8ID86_9PROT Uncharacterized protein OS=Caulobacterales bacterium GWE1_67_11 GN=A2093_02135 PE=3 SV=1 +MTLRSVMFHLDDGDAPLRFAPPFLQFARDYQVRDLVAAAPGRLPdpfvaaafplaqaqarereMYDLIESLQQALCEaaDGFALDFRSAGVLDVTAFLLDQAA--RCDLIVTRQHRALDT--DLGQADLSRLVLQAGRPVLAVPRS +>tr|A0A196NBP4|A0A196NBP4_9SPHN Uncharacterized protein OS=Sphingomonas sp. TDK1 GN=A7X12_17230 PE=3 SV=1 +--MRSILLPLCDPALDRHAISIGTDLADRLDAQVTALLPLTDFAslpvhghypytagwdefiegtqasAERREVEARQAFEAheresgVPT-RLSLRTVYGNEDAVVARAAL--THDLVLFARQSTDEDDPLPTSSLLKTTLETAGRPVLVVNGD +>tr|A0A1F2ZV60|A0A1F2ZV60_9PROT Uncharacterized protein OS=Alphaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_66_14 GN=A3D94_15195 PE=4 SV=1 +-MIKSILAVSEGGPDAAMSFRLAARVAANFDGTVDALHLPVGPAggivgglamsgeampllididderLEARAKESERAYKEiva-PIKGATYTAAQTATLDTLVAMGR--CADILVLGRPGADPE--NVAPATVEAALYECARAVMIAPPT +>tr|A0A1I1GVB8|A0A1I1GVB8_9RHIZ Nucleotide-binding universal stress protein, UspA family OS=Devosia psychrophila GN=SAMN04488059_102315 PE=3 SV=1 +EQNARLLFLLPVATYpdptTKLGLGSALAMASRFGAGVTAVVQEVDITpihsavgeavlgvsrlageaearSRDRVREIREWMQDradrlaVPIELQTIRSRPEGFADDLFPAAR--CHDLTISILDTSD----PQRLAETEALIFETGGAVMVIPAT +>tr|A0A1V2ADK1|A0A1V2ADK1_RHIRD Uncharacterized protein OS=Rhizobium radiobacter GN=BV900_26935 PE=4 SV=1 +MSFATLLQITTGE--pASPESNMDFNLADAMESHLSVLLIGIASPppvgahmesvsaawlderQADQDRLARQVFALenylkgkisSFDIEEAYTE-IFNLDNVVGYRAQ--FADAVAIGPDILND--PGVRDAILDGALFHAGVPILVDPLR +>tr|A0A127VH80|A0A127VH80_9SPHI Uncharacterized protein OS=Pedobacter cryoconitis GN=AY601_3738 PE=3 SV=1 +KKLDKFVFATDMEDSDLNIIQALAEFAKPSHAEITLAHIQHPDTPEadtkklvtGFLEDVANKINYPKI--YYRAVEHTPVKAGLKWLAENVTCNVFVMVHRHKTFLEQLFNLSNTQKMAANTNLPLLIFPCA +>tr|H1YD67|H1YD67_9SPHI UspA domain-containing protein OS=Mucilaginibacter paludis DSM 18603 GN=Mucpa_2986 PE=3 SV=1 +INLKTIVFSVDLKKYYPKAVGFLIDIARIHQSQIITLHIGTNSDINpsQFVNMIQNVFEYTHV--ASKQIPGEDVGEKLEEFLLLAHPDLTVMVHHQRSIFGEFIPGSNSKKMLYRHKTPLLILRD- +>tr|A0A0P0NIL1|A0A0P0NIL1_9SPHI Uncharacterized protein OS=Pedobacter sp. PACM 27299 GN=AQ505_17045 PE=3 SV=1 +RDFGKIAFATNFEHpqQDVEDICNLISLASVFGSDILMTHVHIALTQSvdhqlianELLTGIIQKANYPNI--FYRSVENEDTRTGLDLFFDDEQIGLLVMVHRPHDFIDVILRGSRTQKMAARITIPLLVLPDG +>tr|A0A172TR59|A0A172TR59_9BACT Uncharacterized protein OS=Flavisolibacter sp. LCS9 GN=SY85_02680 PE=4 SV=1 +KGIEEIVFCFDASASSLFAIKEFTYLFPQFQsKKITVLEVRNDiLEEMGEDVAKTREWLEAHYQNVHFRFLEGDVKDELFTYFLLKKDTFIVMGSFGRNMISQLYKKSASETIIKTIDLPIFITHH- +>tr|A0A1F3TX13|A0A1F3TX13_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium RIFCSPHIGHO2_01_FULL_40_29 GN=A2622_00285 PE=3 SV=1 +--PEKILIPCDLSERSHHAVHQVQPFLRAFKAKSELYHVVPQPLPILDFQSYVQFSEKikrseaqkrkafkKKHPQLKIVDSEGGVVEQIQKRLE--NFDLLAISPKTSLKAKP-FFGSVTSKLLRSGDKPILIAP-- +>tr|E7QZB8|E7QZB8_9EURY UspA domain protein OS=Haladaptatus paucihalophilus DX253 GN=ZOD2009_20627 PE=4 SV=1 +--MKRGVIAIDETEAHETLLREAGQWAAAADAKLVVLTFLDESEYEkgvetlesvgkvenvsydtgavteaaaDDAAAFAAGVLDGMGVEFTTVAAVvgdKERGSRVVEAGEKYDCDHAFVVGTGRSPTGKALFGDFAQQVILNFGGLVTIT--- +>tr|A0A1G7NCX7|A0A1G7NCX7_9EURY Uncharacterized protein OS=Halorubrum xinjiangense GN=SAMN04488067_107135 PE=4 SV=1 +--MTRGLVSLEATDAHRDLLAEAAASARGSDDDLVVLWHLDADKYDedvttleavgrienveydhssivdgatAKARSFVTDVLGDSDVDVQIAVSVgseDDRAERVLDAAAEHDCGHVFVLGDSRSPTGKAVFGDFAQQVVLNFEGYTTVR--- +>tr|A0A231MZ04|A0A231MZ04_9GAMM Universal stress global response regulator UspA OS=Zobellella denitrificans GN=CGX12_09040 PE=4 SV=1 +MPYRNILVALELNHREKPLLKRAVELAECHGAALHLVHVEPDVSGiyvgslnmdlrqlkvklrLESGHEIMKMLTDTQHHISSVSLPSGDVRQAVRLAVKEKNADLLICGHQLEHHFLGHLF-SHTVGFLDIDGCDLLVVK-- +>tr|A0A0X8X107|A0A0X8X107_9SPHI Universal stress protein family protein OS=Mucilaginibacter gotjawali GN=MgSA37_02006 PE=3 SV=1 +EELKKVVFATDFDESDMLAIHYLAKLSKLLNFELEIIHIIHPDKSgkekSQKEIELEEQVSRLKYPSVTYHDIKGnDVAENILRIYKESGAGLLAMIHHQHSFIMRMLHQSTTKKLLDNQEVPLMIFPS- +>tr|A0A1C2GR19|A0A1C2GR19_9SPHI Uncharacterized protein OS=Mucilaginibacter sp. PPCGB 2223 GN=BEL04_06450 PE=3 SV=1 +KPIWKIIFATALHDRDIAAASYLVNLARVLGAHLEIVHMLPLAGGeteEWQEARFMHLLENFKYPLITYHRMRAkSISAHLQHEGKEYGADTLALIHYHHGFLTGLFAHGTIRQLLAHHNLPVLVLPA- +>tr|A0A1Q3UIV8|A0A1Q3UIV8_9SPHI Uncharacterized protein OS=Mucilaginibacter sp. 44-25 GN=BGO48_10230 PE=3 SV=1 +NALKKVTLAIPFELADINAINYLTGLGKQLNFHLEIVHVSLLEKSedTIKKNAIVSHINAIKQDNITYLEIRGkNVVKRLNRLCKDKNSDLLALVHYQQGFLSGPFDRSTTVAALDNQRIPLLVIPS- +>tr|A0A1J5DFN3|A0A1J5DFN3_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium CG2_30_63_29 GN=AUK47_23075 PE=4 SV=1 +PPLRHLMATSDFSEDSERGVRWAYQLSRALECSLQLFHAADIPPAaivpgeppywipkiaieeleQRSLVRLKEFVEAEKFDSVSYRCQaSTVVAETIAEAAEAQNIDILVVPSHSRGVVEAFFVGSTTLRVLRLSRVPLLVLPRT +>tr|A0A1W9GKD2|A0A1W9GKD2_9BACT Universal stress protein UspA OS=Nitrospira sp. SG-bin2 GN=A4E20_00915 PE=4 SV=1 +-MYKTIYIPVDNSDHSNTAVDIGVHMAKAFGSKIVGSHVYAAKMHDkrfkqmeaglpeeyhdekeldrqrqihdslitrglqiitdSYLDYVDKKCNEANL-PIERRSLEGRNWKVLAEDINTNGYELVIMGALGVGAVKDSVIGSNTERVVRRVRNSDMLIIKN +>tr|A0A1F3SLJ9|A0A1F3SLJ9_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium GWA2_49_15 GN=A2X86_07670 PE=3 SV=1 +----SLLIGTDFRENSKNALRTGLIWAKQMILESHVTYVHSSPVSRKALKSAhiidqtsEEYLEAsliekiknqvsvldptgSKVQNIHYKILYGQPAIELARQATEMNPELLVLGTKERGPLGQIFLGSVTEKIIQTCTYPVLAVRD- +>tr|A0A1J1A9T6|A0A1J1A9T6_9EURY Universal stress protein UspA OS=Halodesulfurarchaeum formicicum GN=uspA2 PE=4 SV=1 +GSDGDVMVAVEDPAQVAQLVRTARDIAQGYGGTVRLVTVVVKPYESpfgmfsdetivqefaadsHELLDRAP--DPEGV-EVVRDLVVArSVEKGLVSAVKRTNPAALVIGWDSDPRRSDALLGTTVDHVLEHAPTDVYV---- +>tr|A0A1G3TJ38|A0A1G3TJ38_9HELI Uncharacterized protein OS=Sulfurimonas sp. RIFOXYB12_FULL_35_9 GN=A2345_07345 PE=4 SV=1 +---NTVMVCIDHHEESMDAVRYAKRLSDSLRAEFIALQITSEVH-gntrkSEQIRKHLKLAERLGAN--VISKISGDKTDAVIEAIEEYGVTELVMTRPKS-RFLGLLFPNLTKSVMDRKPqCTIDIVPFE +>tr|A0A0P7Z5A9|A0A0P7Z5A9_9CYAN Universal stress protein family protein OS=Phormidium sp. OSCR GN=HLUCCO16_14120 PE=4 SV=1 +--LRYLLIAYDDSNTAKTLVKQISETARNrpenSLEQCLVAWAVESKSRreipqsqtiedaEEKLAAVKQELEQLNLT-VATEVRQEERLQAMMSLAMEYDISAIAVNSPSVPRLLEWSRPNFANLLLRRSWHPVLFFPDP +>tr|K9Z2I1|K9Z2I1_CYAAP UspA domain-containing protein OS=Cyanobacterium aponinum (strain PCC 10605) GN=Cyan10605_0444 PE=4 SV=1 +--NSFWLVPYNHAPHHRYILEKIRGYVEIdkgnTLKECLFLSVIDEVSRseiltenkvkeaENKLAEIQKSFVSSPIN-VQTLVKRGNILEETFKIAFAHDVSAIALADNLKEdsifnRLVQLAVGNNANYLLNCSWFPLIYFPMN +>tr|K1KUM2|K1KUM2_9BACT Uncharacterized protein OS=Cecembia lonarensis LW9 GN=B879_03538 PE=4 SV=1 +-QLLKIYVMVDFSDYTESTLKMVKDWVAGKKAEIKVLHQLDFHLPTlanhdlrlkllydhkrELLNQWFRLREEIFGSsdAISFEILEEPILEYLKK---TDQDAMIFMGLKGGGILKQIFLGSMVSEVIERINYITVAVPST +>tr|A0A136MPN9|A0A136MPN9_9BACT Uncharacterized protein OS=Chlorobi bacterium OLB6 GN=UZ06_CHB003000288 PE=4 SV=1 +-MKKRFIVLVDFSRFSAPLMRYVSSWSLEADAEVLLMHQPTPFYPIfitpetrrtitrhtkaEALKKMDLLATSSIDHrvTVKLLAPIKPLWYILNRTLKQPYDSIVVTGLEDAGFLRQLLDPKSPVQVIENTSNLVAAIPGG +>tr|S2E1W8|S2E1W8_9BACT Uncharacterized protein OS=Indibacter alkaliphilus LW1 GN=A33Q_1125 PE=4 SV=1 +-MSLKLIVPIDFSKYSLQQLRLAAAWKEKYGIEIMILHKVDLVFPSlanadlrlkmeynlkrEAKNNINELL-eevGLDIN----NETqiiSGSLIEFFKNSPKVSKDDIIVLGIKGLDTFSRILIGSTATQLIDNLEHVIIGIPLD +>tr|S7WRC8|S7WRC8_9BACT Uncharacterized protein OS=Cyclobacterium qasimii M12-11B GN=ADICYQ_1779 PE=4 SV=1 +---------------------MACSWQEIFNLDLVFVHKMDGIAPTlpisnkkeideiiefnkk----ESKTKFLkylqegALSPDsnKTSFEAVSSQLAHFL--EGFLKPNDIVLLGLKGTRFLKKILIGSTASTLINQLNHIVIALPRT +>tr|A0A1M7P7A4|A0A1M7P7A4_9BACT Uncharacterized protein OS=Cyclobacterium lianum GN=SAMN04488057_10794 PE=4 SV=1 +--MKRLIALLDFSEYSVPLIQMAYQWKVHYGMKLVFVNRVPGMIPTvadkttrkqlisfeke----EAKKNFLdlldktNLNHSDDIFLAIDKPLVPFL--KTYLEPNDVLFLGLKGTGPLKKFLIGSTATNIINQLNHLFVGIPKT +>tr|A0A1M7ZXG7|A0A1M7ZXG7_9FLAO Uncharacterized protein OS=Flavobacterium cucumis GN=SAMN05443547_1910 PE=4 SV=1 +-MRNRTITLFEFSEDNEKLINFSNNLATEINSNLLLVHQTDCLIPSftdsetkkkilevekkEAIAKINEIIDL---KthDIECEITEKNVVNYLESLHDSSVCDWVIVKQKEKEEFERFFTKSTILKIIEETNSLLIALPQD +>tr|A0A1M6ER69|A0A1M6ER69_9FLAO Uncharacterized protein OS=Aequorivita viscosa GN=SAMN04487908_106133 PE=4 SV=1 +-----------MIGAKKPMQKFYCII-------------KHPFLPTfaeneardyiiqqendKARAKLKALAEELIPDfiEVSFYVSEIDFHQTLPQLLSEPFENLIFIGLQGTGVLKKLFLGSVALRIIGNTDNTVVAMPKG +>tr|A0A1M7XXG1|A0A1M7XXG1_9DELT Nucleotide-binding universal stress protein, UspA family OS=Desulfopila aestuarii DSM 18488 GN=SAMN02745220_00449 PE=4 SV=1 +QQKGNILFATDLSINMHKVFEQAALMAINFNTKVTILHVLVDNPEAKrhmmsifgddqyqnirrehqeraqkvltgkntearkiqqaltkvfFEQERKLNFTDTDTFIDKILIAEGpSIADEIYSTATDEGCRCIVMGCPSQGLLSGALGDKILKKVLKVSKIPVLVVP-- +>tr|N1MKL9|N1MKL9_9SPHN Putative universal stress protein OS=Sphingobium japonicum BiD32 GN=EBBID32_16180 PE=3 SV=1 +RRYRDIVIATDFTEASLQALQTVAAFF--PTSDLTLFHGYDIPYAGFIVDRdieselrsiekeittkfmADARITPNVKSRTAVMIEHGSPDALLGDFIDEHSSDLTVIGSHGRGAIFDALIGSNAKRLVERLEGDLLIIR-- +>tr|K8GGZ4|K8GGZ4_9CYAN Universal stress protein UspA-like protein OS=Oscillatoriales cyanobacterium JSC-12 GN=OsccyDRAFT_2720 PE=3 SV=1 +-SLRHVLLVVDNSSATQQALAVIYQLVGAGIHQLTLLHVQPPLNVsylvspfvarsssrqlnqslqdaqreqgEAILQRALTAIVIPSL-EVQTRLRIGDPGPTICQVATDLDTNLIILGSDPArrsllsplqamrvphrprpesnniSILRNTRLSVTEDYVIHYAPCPVLLCRTN +>tr|I4Y9R3|I4Y9R3_WALMC Adenine nucleotide alpha hydrolases-like protein OS=Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66) GN=WALSEDRAFT_69627 +NDpenhDRRVLIAYDESSESKGALQHYIDYIAQDNDHIFLVTVLRPLErhldysvycaeeeatdagrkidprigaFFRDRNDALKRLKEEREritpllaprnITLTLHVAHGDPRETIPRVSKWHSAQLIIVGKRTLGRWQKIFHPSVSLAVIEHTKTSVLVV--- +>tr|A0A1M5YCF2|A0A1M5YCF2_9DELT Nucleotide-binding universal stress protein, UspA family OS=Desulfofustis glycolicus DSM 9705 GN=SAMN02745124_03851 PE=4 SV=1 +---TRILIALDSSPRAIHLAEHAAKMFDCRKLSITLFHAVRGISVSmqglesifpddyaknitqdaqakidPIFDRAKSVLIEAGVAadNIAIKTVNGVSSraTAIVEEAAKTGCGTIVCGRRGVTQVADFSMGRVANKLTQLVH--------- +>tr|A0A0R1ISH1|A0A0R1ISH1_9LACO Universal stress protein UspA family nucleotide-binding protein OS=Lactobacillus farciminis KCTC 3681 = DSM 20184 GN=FC68_GL000 +-------MAIDGSQNSNRAFNQAVQLAQRCNANLYLTRVVedyylneddgilqmvnyeDDPEVVAARDDLNQKFMMTVYPITDTFLRIGDPKKIIADYlVRGLKIDLLVIGKFGKNNNRRTNLGKIARFLKNNVSCQVLIV--- +>tr|A0A1X4GL98|A0A1X4GL98_9EURY Universal stress protein UspA OS=Halorubrum ezzemoulense DSM 17463 GN=B9H04_10255 PE=4 SV=1 +GRFERVLVVATDDPAGRAAVSTAVDLAATHGAVVDALYVVDTAEAWdvvverrertgeELVEAAEDAGAAVGV-DVEKWFRYGTTHREAVDFAAAHDADLVVVGSARRTGLDRLLRPDpVPARVRRGADVPVMVVGPD +>tr|U4L883|U4L883_PYROM Similar to Universal stress protein A family protein C25B2.10 acc. no. O74782 OS=Pyronema omphalodes (strain CBS 100304) GN=PCO +RRSRTFLCGTDQNDYSEFALEWLIDELVDDGDEIVCLRVVDKDSkissdqamqeklyrqeATKLLDQIIEKNEDEKAVSIILEFAVGKVHETIQRMIHIYEPVILIVGTRGRslGGLQGLLPGSVSKYCLQHSPVPVIVVRPS +>tr|A0A160NTH1|A0A160NTH1_STRLU UspA domain containing protein OS=Streptomyces laurentii GN=SLA_0833 PE=3 SV=1 +--PSSVRRGRRGRQQGLPG-----GRRLRRGGGEPARGTTACPLGvvplllshdnvaqelsersRLLAESVAGCSERYPDVDIEQEVVRGHPVEELTRASR--ESLALVIGRRGHGG--------------------------- +>tr|U9SX93|U9SX93_RHIID Uncharacterized protein OS=Rhizophagus irregularis (strain DAOM 181602 / DAOM 197198 / MUCL 43194) GN=GLOINDRAFT_284888 PE=4 SV +-MGKKYLIPLDGSDHSKYSLLWAFENLINPNIDSVLLLSVGVLSAgtpceysavtrnilngdneidlerQKAEEKAKEIVNDGKLivknllktqeLPIECFVSsNSDPGRYIVNLSREQKIDVLVMGHRGTSSPDATNTGTVAQHCMHSAGCTVVITR-- +>tr|A0A167HII5|A0A167HII5_9FLAO Uncharacterized protein OS=Ulvibacter sp. LPB0005 GN=ULVI_08680 PE=4 SV=1 +--MKKILIPIDFTFKSYDAIDYAVSFFKREKCHFYFLNTYSYDieglnavnllqagddffekPKRESEMSLGRVIQKITSKcenkrhQFNAISEYANLIEGVRKAIKELDIDLVVIAGKVQTKRATDTYSKNTKRILDNIReCPVMIIPAS +>tr|A0A1X7L5D7|A0A1X7L5D7_9BACT Nucleotide-binding universal stress protein, UspA family OS=Dethiosulfovibrio salsuginis GN=SAMN06275492_1478 PE=4 SV=1 +-MFKRVLIAIDLKQNPDDLISCISNLKLKSIEKVLLLNVIDDRINpsfdkdviAAKLEEYGLKLGLPGD-KIETQISTGLPFDEIICQANRWEASVIAIGPGHGPTWASSWIGSTALRILEYSPIPIMTCNSG +>tr|C6L1E5|C6L1E5_9BACT Universal stress protein family domain protein UspA OS=uncultured bacterium PE=3 SV=1 +MSIRNILLAHSGTSGFPSSLGHAIRVAKKHNAWLTCIYSGSTSFFDqvlvlsdelreklgavrtAKIDDLRQQFDQEAAAagigeKAQFLLPATVGKLTISDVAR--NFDFVVTGYHA-KLPNDEYRAASPDLIALQSGRPVLVVPDG +>tr|A0A154KWK1|A0A154KWK1_9PROT Uncharacterized protein OS=Thalassospira xiamenensis GN=AUP41_16485 PE=4 SV=1 +MALKDILVPYNGQNTANCALKQAILLAEKHAAHVTACFPYDPPAVVstarqlmskrleeqfhqivdrmevEARSAIRQAFDEQVAGvsvpeRVHSLEIIGNSDIAVTKAAR--HFDVTFIGQNL-SGYSDGSNMIHPDVIALRSGKPVLVVPHR +>tr|A0A1B0ZMG7|A0A1B0ZMG7_9RHOB Uncharacterized protein OS=Phaeobacter gallaeciensis GN=JL2886_00442 PE=4 SV=1 +MAMRNIVMPIAPGRYDPSSLRRAITLAKRLPCHLDVVFLLPDPKETfiytgiepteqdgplsdirdrmedhgrSAAEASRRLFAKLRKEaglelrqkpslastaSGAWHRIKGEPQEMITPLAR--RADATIFTPETARY--TLMADNVLEAALLRSGRPVLYLPGE +>tr|B0BZR2|B0BZR2_ACAM1 Cl-channel, voltage gated, putative OS=Acaryochloris marina (strain MBIC 11017) GN=AM1_0946 PE=4 SV=1 +---GRILLPLANPDTAEPLLKVAVAMAQALNYELECLHIIRLPRNrlpaetpvqtvkgRRLLQKAIRYGQRHQV-SVHTQIIaAQDVAQAILEVEQTEHINLLLMGWQGQFFSGGQIGNPTVRTILQQAKSQVLVIR-- +>tr|A0A075FHV8|A0A075FHV8_9ARCH Cl-channel voltage-gated family protein (TC.CIC) OS=uncultured marine thaumarchaeote AD1000_100_C06 GN=TC.CIC PE=4 SV=1 +---SRVLVILQEDSEinRRSLVSLAAIIAKKKAFDLECLHVQANTKSdndhRLLVQQAEAVARELVV-TVHTSVRlAKHQATAVGEIIDRRPIEMVVLALNSATDL------IELELIVEQTTCPILASS-- +>tr|J6J0I3|J6J0I3_9RHOB Putative stress protein UspA OS=Rhodovulum sp. PH10 GN=A33M_4302 PE=4 SV=1 +--GRRPIFAWGETAGAARALTDALPLLSpDADALVLYAYERDQ--RNDFAERVIPHLERHGVKarFEPFVLEEETVMDVLLNFASDHGADLMTLGIAGRAGAGRFERGRGGMPTLRQLTVPVLC---- +>tr|A0A0D1ZCM9|A0A0D1ZCM9_9EURO Uncharacterized protein OS=Exophiala mesophila GN=PV10_03736 PE=4 SV=1 +RAGRLYLVCSDLSTEASYAMEWVVGTMLRDGDTLLAVYAIEDENAGktteadreilqaegtqagkdatdvmatltrqttqgggtsvgldlrnkyipatEaqsltgsvdarktskkqmerlraveeITGNFIKLVRKTTLQ-VRCMVEvihCKSPKHLILGAIDTLDPTLCVVGTRGRSSLKGVLLGSFSNYLVTKSSVPVMVAR-- +>tr|Q0CYD5|Q0CYD5_ASPTN Uncharacterized protein OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=ATEG_01299 PE=4 SV=1 +RRRRKYMVATDLSEESVYALEWTIGTILRDGDTMFAVCAIYDESASsatqngdgakamqdvaavvgsqteettlkpnndsgtnlprailgrlgtGtdskpgsvdsrgmskteservravesISQTCVRLLRKTLLQ-VRVAVEvihCKSPKHMITEAIDGLDPTLVIVVCSWVRSQTT--------W--------------- +>tr|A0A1V6I5F1|A0A1V6I5F1_9BACT Universal stress protein UspE OS=Bacteroidetes bacterium ADurb.Bin035 GN=BWX61_00762 PE=3 SV=1 +DRIKSILLPIDSTAETTNKLPWAIEIAKYSNAEIHIFGAYITDlstmknKVDKNIVMIENELEKENIKFKSFKKSITNYTSDLISYIEDNNIDLAIIMTEQENRNTNVLLGQYAMQMINHCPVPVLSVHQD +>tr|A0A1E3WB02|A0A1E3WB02_9RHIZ Uncharacterized protein OS=Methyloceanibacter marginalis GN=AUC71_12265 PE=4 SV=1 +---ETVVIAWKDAPEAVRAIAAAAPFLEAAK-RVRLISIAEDGeEEEdDTASAMTGYLAMAGLPVEMETVPLgGrEVGDACSRPPA---------AAFSSSWAGMGTGGGANGSSAARrsmscatRTSPC------ +>tr|A0A1J5BRL5|A0A1J5BRL5_9BACT Uncharacterized protein OS=Caldisericum sp. CG2_30_36_11 GN=AUJ99_00915 PE=4 SV=1 +-MFKKIMIMVDNSSIMEDVVQYVTNLF--PDAFYYLYGVINLGAFsgyysrivsqqmreisSETLKTLSLLLESKGIK-FNLFLDEGDPVSTSLAFARKNEVDLFVLETHAGLSVNKIKLGKTTLSVIQHSHIPLFLVGED +>tr|J3N5A3|J3N5A3_ORYBR Uncharacterized protein OS=Oryza brachyantha GN=102703338 PE=3 SV=1 +RYRQLHETEMHPAGTHPANdDDHHDL------------------------------------pn---------------------------------------------------------------- +>tr|A0A1M3DT88|A0A1M3DT88_9FLAO Uncharacterized protein OS=Chryseobacterium sp. 39-10 GN=BGO40_07230 PE=4 SV=1 +NAIKNILIPLDFTRRNEKFLNIAAAVANRHGAKVHVLNVIPFSllgtgsvssgkfffhenamieSAEKQLATYRMVMRKITNEDVIAQHAIGAVATEVLKYSKQKNIDLILMPVQYPKRRPG-FISSNTYEIISNSAVPVMTIPEN +>tr|A0A0Q5ZDC9|A0A0Q5ZDC9_9BURK Uncharacterized protein OS=Ramlibacter sp. Leaf400 GN=ASG30_08695 PE=3 SV=1 +TEIRQLLVHLDAGRRIRETVSCARRLAADHGACIAAVHAPVPAMAElpivpglgpaaqsflefqkerrRAVHASFERAMRdpGPAVEATWGEVNEFPLaGTFAEAAF--SADLLVLTQPDPQHRAEDVPHDFNEAVVAASGKPSLILPPS +>tr|A0A246Q1Q0|A0A246Q1Q0_9BURK Universal stress protein OS=Achromobacter sp. HZ28 GN=CEY04_28060 PE=4 SV=1 +-MYKRIAVHVDRDGAFERRIAAAVGLAQAHNGEVVGVYVQDPPYVYgynesltptavlevqrrlinderQQVQRTFEHLTASAGVPNSWSSVEGLRDVELAVQAR--SSDILILSQPDADFSrRSSIEPYQLETVIMTAGRPVIVVPYD +>tr|A0A0N0TBD5|A0A0N0TBD5_9NOCA Universal stress protein UspA OS=Nocardia sp. NRRL S-836 GN=ADL03_01870 PE=3 SV=1 +MSSRPIVVGVDGTPASDQALEWALDEAAVRGCPVHVVHAWTFEALtdwtetTEQRTRAESEAlidkavqaaaeKRQEMPEIVRQSLRGEAAETLERALE--GAAMVVVASHTGHRLRQIVLGSTSMHVVRHAHAPIVVIPVD +>tr|B6EGV0|B6EGV0_ALISL Universal stress protein OS=Aliivibrio salmonicida (strain LFI1238) GN=VSAL_I2982 PE=3 SV=1 +KLYQTILLALNPDDSkAHKLMVKAGVLAKQNDAELHVIFVEVGIGDvnymdvelelesshnaleFKRIEQLSILSKESPYPVRAVHIADGNIVKHISEIGDKINTDLVIIGYHKSKIH---WGRTLGDEVSDKLKCDVMIAQ-- +>tr|A0A132N7F7|A0A132N7F7_HYDSH Histidine kinase OS=Hydrogenibacillus schlegelii GN=TR75_07135 PE=4 SV=1 +---PKILVLVSDGGNAERLIRRGWRIAQRMKAELFILHVPTKPadRLseaeRKKLREIEALAKILGGKFFIRAAGGRPVIDVIVEFIKENAITQVVLGQTGMSRWQEILRGSLANRIMERTRfVDVLIVGNG +>tr|A0A1R1R2C7|A0A1R1R2C7_9BACI Histidine kinase OS=Bacillus paralicheniformis GN=BVL54_12525 PE=4 SV=1 +---EKILVCVQHGKNAEKLIRRGWRIASRLKADLLVLNVSRTSkeQLapteRDKIGQWETLCAQFGAEFIFKHSNKRRISETITDTAKQHGITQIVLGQSARSRWEEIRKGSIVNSIMRHTDgIDLHIVSDE +>tr|A0A1S1FST7|A0A1S1FST7_9BACI Histidine kinase OS=Bacillus sp. HMSC76G11 GN=HMPREF3291_02140 PE=4 SV=1 +---EKILVCVGYGPTAEKLIRRGWRMANRLKAQLFILNVTKNSpeAFtqeiRERTEQWKILASQFNAVFLLEQEASRKPAQVIIDIAKQHHITQILLGQSARTRWEEIRKGSIVNTIMRKTEnIDIHIVSDG +>tr|D2S2I9|D2S2I9_HALTV Uncharacterized protein OS=Haloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / NCIMB 13204 / VKM B-1734) GN=Htur_4822 PE=4 +-MGGHVLVVISRTAPSTDILEYAFQKY--PNAKITVIHVTTARSPFdpfrnrdpceyvipelgseqseellpapdlftraqqkraeNVFSRAYELSERYDK-AIESVVRSGDETEEVVTYAENHAVDQIIIAENSLIEL-PLFHQNVSESVAHTTSIPV------ +>tr|Q9HIM9|Q9HIM9_THEAC Uncharacterized protein OS=Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) GN=Ta130 +-KFDRIAVPMAEGRSSRRVLHIAFAFASAMGSEITAITVRDQAKDITWTNkitvvtNAYKEGLSQNIKVVPKILTSSDVKSALVEELNRHSYDIVIIASEKRSIITRITSGPVSNYVIKKSNIPTALV--- +>tr|A0A0D2GK78|A0A0D2GK78_9DELT Universal stress protein OS=Dethiosulfatarculus sandiegensis GN=X474_05390 PE=3 SV=1 +KRFRTILFCADEVEKPGSVYALLEDLGEVKGIRLHVLHVLPSLHRYmptetildqssgqvtqassEFMEKTLSKLRrcyphpEGQPGKYRYKVCVGTAYVEILRYIRENPVDLIVLGAMGPSKYGRTHYGSTVEKVCAKARCPVVIV--- +>tr|M0M3F7|M0M3F7_9EURY Amino acid permease-associated protein OS=Halobiforma nitratireducens JCM 10879 GN=C446_07397 PE=4 SV=1 +----NLLVAITEATperARRDMLRVALDLGRLRSTAVSVVEFSDEPehilpsrhsrvrstaLPAWFPDdpedapdwfpsealegdlrtsggepvaATLEDPDGHDTQVDYRRIVSEDHKEAIVDFATFEGIDLILTQRHASNGi-PGFLGTDETAWLRQNAPCDVALVED- +>tr|A0A102CZ79|A0A102CZ79_9BACT Universal stress protein OS=Rhodothermaceae bacterium RA GN=AWN76_01955 PE=4 SV=1 +----RLMVALANPHHEADLLRLARFVatGRTAGGDVVGIHLHRVPlqtpldvarerldervsVERTIARllqqetlPAADGLPLARTRITTVTDVAHDVFGSLISETQRREADLLLMGWQGGFT-VGRIYNSPVQRILAEVRADVAVLKN- +>tr|X1A1K0|X1A1K0_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=S01H4_00620 PE=4 SV=1 +----KILVPVKNPKTAKSLISLAGFIarGNEKL-TVTALKIVKVSqnisisaaqkyilkkpnYRKIL-Hmvenfa------KKKDISIHTILQAAYGITSGILSMVREINPRIIILGWRGPIT-FHRIYENPTKDIIEKSNCDVAVLMD- +>tr|U1PGC3|U1PGC3_9EURY Amino acid transporter OS=halophilic archaeon J07HX64 GN=J07HX64_01185 PE=4 SV=1 +----RVLVALWDSGetdHRSsnreDLLDMIsVLESHSLDVDVQVVEFEQARketfskqhtE-----Iaadtpaw-----IQ-AYDDVSYRRVTARDVRQSIVEYASYNDIDIVAHGFVPDAG-PVGIVADDLEWAIKNTPCNSVVLAG- +>tr|A0A1I0JP09|A0A1I0JP09_9EURY Amino acid transporter OS=Haloterrigena hispanica GN=SAMN04488694_15310 PE=4 SV=1 +----HVLVETFEGEtn--PLLCTLMNAFAEEFDADLEVLAISKIPpqtpivepvshaDADWKEPiesaht-----LDRDEHTVSFEQIRTHDRGAALIDAIR-EKTELVLIDWHDPIR-KYHFRESHVDEILRSpLPVRLAVLKY- +>tr|A0A238VWT7|A0A238VWT7_HALVU Amino acid transporter OS=Halorubrum vacuolatum GN=SAMN06264855_104170 PE=4 SV=1 +----DVLVALTESTtpeAARDMTRIGLDISRLRGGLIDVVRFDSHPhrvftahtdrleeptgtLGDWLGFgeeppswfpmesaeesagsradgsgsrdtdsttsrgdggtealahppeEPLRVEEPERGRLQRHVVSTENVVDSVAAYAAHEGIDLVLAERQTADL-HRALFGGETAELLREVPCGIALVED- +>tr|Q6FCQ8|Q6FCQ8_ACIAD Uncharacterized protein OS=Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) GN=ACIAD1277 PE=4 SV=1 +---MKFLVGYSNDSSGKDALKLGVALAEMTQGKLIVCHIVAKTWHNialakfdedydqflcdeaqKALDDAKLAV-PSHIEARYIARTALSISEGLKQTAKELSVDCMVISGARIAIKGQFFSGTVADELLNQLSLPVALAPKG +>tr|A0A0H4W541|A0A0H4W541_9BACT Universal stress protein UspA OS=Rufibacter sp. DG31D GN=TH63_07600 PE=3 SV=1 +-PIHNILWVADFAYEKQPqrSISLIKVLQRIFGAKIHLLQILQKEDAHqelALRENMMRFANNLQLENYELHFHRDfKVPTGVRNFNQESEKNLVVIGTHARKGVNHLFYGSIAETLVNHCIRPLLTYH-- +>tr|A0A1J4LQE8|A0A1J4LQE8_9EURY Universal stress protein UspA OS=Natrialba sp. SSL1 GN=BBD46_19905 PE=4 SV=1 +-DIDSILVPIAGGPHEGLALETASALATQHDAVVHLLHVRSETDPAQREGEANALLLNAsdefdSETEIRREVAvDDHVAGAITDRTT--AHDVTILGVSRGGFVRRTLLGTISEAVGRNASGTVFLAKRY +>tr|A0A226WLU6|A0A226WLU6_9BURK Universal stress protein UspA OS=Caballeronia sordidicola GN=BSU04_43250 PE=4 SV=1 +-GFKRILLCVDPTAASARAAAFVPHLANK-ETRVRIVGVVENAHAviplgplaafhlsaanalllqdvENACAASQELFASSGAKleirIIDLITHGGGVVHALAKAAQDWRADLLVMGSRQHQGLLHWVEGAVSEPLMKFAACAILVLPE- +>tr|A0A150IFA8|A0A150IFA8_9RHOO Uncharacterized protein OS=Sterolibacterium denitrificans GN=ACY05_00260 PE=4 SV=1 +-MLQKLLIPVKNGEDARQAVAYAIRRRAEGvQVAVCLLHVEESGPGGDpgvvwhellektrhsrprPFDIALRLLFGLDI-DVAAYVRKGAVAFTILDAAEELDCQEIVMPAPHSGLlpFRWLSRNVVDTLLARQRSVRVVAVNRD +>tr|W0SIV1|W0SIV1_9PROT Uncharacterized protein OS=Sulfuritalea hydrogenivorans sk43H GN=SUTH_02057 PE=4 SV=1 +-KVRRLLIPVKSAKDAGHAVAYAIRRRAEGlGMAVCLLHVEESPTQWQalsanaearavkrrradhIFAPAMRMLEGLDI-EFAAYVRSGPIVFTILDAAEELACDEIVVPEPGRGVFSLLSRRVVPVLMARQRSARLVAVTNA +>tr|M5WBX5|M5WBX5_PRUPE Uncharacterized protein OS=Prunus persica GN=PRUPE_ppa011515mg PE=4 SV=1 +MDVRRIVVVVEDVEAARTALKWALDNLVRYGDLITLLHVFSTSrsRNknktrllrlkgFQLALSFKDICNTFPNTKVEMIVTEGDQdGKKIAAVVTEIGASTLVLGLHDHSFLYRLAMAHGSSSIANKLNCRILGIKQP +>tr|A0A1K1QRL1|A0A1K1QRL1_DESDE Uncharacterized protein OS=Desulfovibrio desulfuricans GN=SAMN02910291_02149 PE=4 SV=1 +SAPKNILLLLDEES---PAAAEAVRIARESGAALTALFVLDSTWNdyvghdwlsgsgsradfidymqqeeeKSAARAFTRLREFAGDQmEIHCLTTSGNVIDHARQEMVR-GYDLFVAANPLRRGLER--IRGNVGALCENAPCRILLVPAA +>tr|A0A098LK72|A0A098LK72_9BACT UspA domain-containing protein OS=Sporocytophaga myxococcoides GN=MYP_3823 PE=3 SV=1 +--MEKLLLASDFSDSSNNALDFAKGIAAKAVSEVLIFNSAPLPVLEptiptfmmeeiledqeysakEKLRESCDLVSSERYfdgsrVSCGYKFSSGVAVNEIAEVAQKENVELVVMGAYD-NSITSKWIGSTTISTLDHVACPVLAVPTD +>tr|A0A1R4JYV8|A0A1R4JYV8_9MICC UspA OS=Micrococcus lylae GN=FM125_11410 PE=3 SV=1 +---MTILVGYAPRAESRAALNKAIDIARTTGERIVVVNAGPGGEHrssnllnEAQQRDLQQVLDGCGVDaEFRQYARGRSTAAEMKEVAAELEPSIVVIGLRRRGAVGRFMMGSVSDELLRELDQPVLCVK-- +>tr|A0A158RF96|A0A158RF96_HYDTA Uncharacterized protein OS=Hydatigena taeniaeformis PE=4 SV=1 +RRVRKILFPIDDSENCSIAFKWYLNYVRLPGDFITFVHVVEPLYTSGEMRidmenpevrfedvpktvesvmnrskalglNYMSLAKEAGLESRAFLHVDTQPGRAILTSAKNHNVDMIVMESKGQGILSGASLSRVSDYVVHNLTVPVVIVHAE +>tr|A0A1G2PXS6|A0A1G2PXS6_9BACT Uncharacterized protein OS=Candidatus Terrybacteria bacterium RIFCSPLOWO2_01_FULL_58_14 GN=A2991_03220 PE=4 SV=1 +----RVFVPVARDEDMRGMLEIGIALAKGREAaDISLVHIDETPGDhragreaehiate-PLLVRLVDRGREEGVGVEGSIIESDDPTRTALGIIAIHRMNLLVAGWDGHA-RQGRIFSSKVDAMLREARCDTIVVK-- +>tr|A0A1G1ZRY8|A0A1G1ZRY8_9BACT Uncharacterized protein (Fragment) OS=Candidatus Harrisonbacteria bacterium RIFCSPLOWO2_02_FULL_41_13b GN=A3I24_02355 PE=4 SV=1 +----RILMPIAPHLSldeIKNLAEIAFVLTSKYDGELVIVTVHEIHHAlpldqsmihpdliakeKEIFNQLqqwvakynqKTGPEVKDINFHSLILIGRDVVDVILEVIKMEDCDLLMLNWSGYRDGLNVILSRKIDRILRESKCDLLVVK-- +>tr|Q1NSH8|Q1NSH8_9DELT UspA OS=delta proteobacterium MLMS-1 GN=MldDRAFT_5054 PE=4 SV=1 +----NVMYATSFRQAHGVCVNFIKHPAFQAK-RLILLHVGRRAPDPEAEGKRLEQIKInleqlardcqDGFATIEKKEVVGLgVARKILRQARTSNIDLLIIGKVDTGGLLSSFTGSTAEAIYNSAPCSVLVIPG- +>tr|A0A1N6WCH0|A0A1N6WCH0_9SPIO Nucleotide-binding universal stress protein, UspA family OS=Alkalispirochaeta americana GN=SAMN05920897_11718 PE=4 SV=1 +----VVLYATALQRQDEYVLPLLSWPRLKVD-RLVLVHAGPRAPDPVAEHHRDQDVSRrlgalarscdIPGCLVDTRSVTGNARREILRIARHEGARLLVVGKSEKQGSLAEMVGSVAEAVAYNAGQSVLIAGQ- +>tr|A0A0H3K5J5|A0A0H3K5J5_SYNP6 Potassium-transporting ATPase D chain OS=Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) GN=kdpD PE=4 SV=1 +---ERVLVCLSTHPQSIRLLRRAARLSGAMDARLYVLFVADPqrfltKAEVLQLETCDRLCGMFE---GAFLRVE-stDVVGAIVKVATEQRVTQVVIGESPTSRRLWWWQRPLTDRLLQRLRgqgIDLHIISFP +>tr|E8V6Y1|E8V6Y1_TERSS Osmosensitive K channel signal transduction histidine kinase, sensor subunit KdpD OS=Terriglobus saanensis (strain ATCC BAA-185 +---ERVAVCISANPEARDLIARGARLAEGLNGELYVLHLTNErdnePERRKTLDAHLQFAMNLG---ANIVHLT-gkSVASATAAYVTEHRITQAIFGRSALHGLKKYLYYLAIQKFMSEAPhVDLHIITQD +>tr|Q7X1J7|Q7X1J7_9BACT Lfe123p5 (Fragment) OS=Leptospirillum ferrooxidans PE=4 SV=1 +---GCVLVGVSDRPEDAALVRRGAVLSDRLNLELKILYVRKEade---GLHSQVLVDLTRSFG---GVFLSEV-spqKWESHFIRRCQEIGPSLVLLGQSAWRPGFE----STAEMIARNLNqFPLLIIPLD +>tr|G4HHP8|G4HHP8_9BACL Osmosensitive K channel signal transduction histidine kinase, sensor subunit KdpD OS=Paenibacillus lactis 154 GN=PaelaDRAFT_350 +---EVIYVLVGSGPESERIIRRGFRIAYRLKAAWYVTPLPDRsedgkLSMPARRDPFQAMTERLG---GIFRPLELqgkqayDLPALLIAAADEVKATQLIIAQPPG-nGFPGSSQMRFAKQLLRRARhMDVLVISDG +>tr|A0A0S8B8W9|A0A0S8B8W9_9CHLR Uncharacterized protein OS=Anaerolineae bacterium SG8_19 GN=AMJ56_12300 PE=3 SV=1 +--FADILVLLEGIEDDWKVLDTVIKMASWDKDRIFGLHVVKdrsqvnSPAVQYICTEFERRCQAAGL-VGEFAVEVGILFERIVERAA--WADLVVINLTHPPQSQPLaRLRPGWNQLIQRCPRPILTLPN- +>tr|A0A098LFC6|A0A098LFC6_9BACT Uncharacterized protein OS=Sporocytophaga myxococcoides GN=MYP_2421 PE=3 SV=1 +-MISKIVCPTDYSDNSFNAIKYLKDLAALSNANIELVHVETPIPH-SLSSEMEELLQDIK---HEKLVLWGNVTDEIVNEITKTHADIVGISSLGKNKEENFFISKVTLSIVNQSSFPILIIPPD +>tr|X8J719|X8J719_9FIRM Universal stress family protein OS=Mogibacterium timidum ATCC 33093 GN=HMPREF0581_1288 PE=3 SV=1 +--MKRILVPVDGSPRSLIALEQLKNTFSPKAFEVVLVMVRENTGYaltmaeeaeirEELDKRLTSIAKTIDNYKVITRSAIGRAGARVIEAAKECGVEMIVMTKSTKPGSGSS-IGLTASYIIRHAQCDVMIVKET +>tr|A0A126YU99|A0A126YU99_9BURK Uncharacterized protein OS=Burkholderia sp. PAMC 28687 GN=AX768_29730 PE=4 SV=1 +----RLLIPIINACVVTEAVRHATVLSKnTRDVTVELLEILPPPDqgrvvafhsisdqradelraGEAAVLASRAMLSQANI-LFTLTRVFGIPEQIIAAFVREHECNAVLIDTSSPNAFRTL---SLVTRIWRLTTIPITLLH-- +>tr|A0A1G1ZIB1|A0A1G1ZIB1_9BACT Uncharacterized protein OS=Candidatus Harrisonbacteria bacterium RIFCSPHIGHO2_02_FULL_42_16 GN=A3B92_01290 PE=4 SV=1 +SL-LLAAHPSGNSPYLKLMGEIFSSLKNYYKAKTELTSILAADTPFYLKPDPQILLKPLGLKRKDfeeiEFFKAKSVITAIIDEAKIKEISLVIIGATRPKFLGEIRFGNIPELLSKHLNTSLMIVRG- +>tr|A0A1G2DCL3|A0A1G2DCL3_9BACT Uncharacterized protein OS=Candidatus Lloydbacteria bacterium RIFCSPHIGHO2_02_FULL_54_17 GN=A3C93_05460 PE=4 SV=1 +MDRVFIPVAVDANPNLRFTGKVATALYRTFGAKVTVAMVVPEDVRgkgdEYYRSILEERVVELKMKIPGgvesKVIFSDYVASGIL-KSTEGAYDVVLLPAARGGITKVIGVGSIPEQVAKQCRrKTVLIAKG- +>tr|A0A1S8VRW8|A0A1S8VRW8_9FUNG Uncharacterized protein OS=Batrachochytrium salamandrivorans GN=BSLG_05077 PE=4 SV=1 +-----SIVCIDRFPDSETTFDWACHNLvspppveHmsdsPPSEGLVLLHVVSPKELAlfwkstspvwtsmgksdahspiarhiddsirseytgkheptatdlkialdqiaskllsYYTARVIATQQSLNFPLRAVAILSNSPKDAICSTSSTAHPKCMVVGRKRAISFKSLTLGSTALHCLRHCKCTVVVVS-- +>tr|H0F862|H0F862_9BURK Uncharacterized protein OS=Achromobacter arsenitoxydans SY8 GN=KYC_14802 PE=4 SV=1 +-MFTRILVDFDPEHLSHSSLLGLLDLAAANHSALTFLALRPKLDELlcasedefvedvrrqiaDEWGVIMSLARQRGL-DPRLEVLAGDPIEALLGYGREIDADLIVAGKSHSGGIRNAVLGLPWKDFLTRADVAVLILP-- +>tr|A0A084IKH2|A0A084IKH2_9GAMM Universal stress protein UspA OS=Salinisphaera hydrothermalis C41B8 GN=C41B8_10815 PE=4 SV=1 +-GYETVLLDASSVQHRETIWDYTLRLAVQHGAYVTAIHQGA--peighsgdpgqldvyserretelvhKFE----ALARRY--AGVQ-YEWRS--deGDRVERVARHGL--YADLIVMGQFDPSDR-GGlGTYEDPVEIALMSGRPVLVLPRS +>tr|A0A1E3VTM3|A0A1E3VTM3_9RHIZ Uncharacterized protein OS=Methyloceanibacter stevinii GN=AUC70_13995 PE=3 SV=1 +-AIKDLIISFDSLTAPDAQLPYAVEATEALGAHAIGVAHVPAGetaprae-AQRAMDRFASAGDQRGIS-WETRLATcatGKFAEQLSVQAR--HADLTIIGQPSSEGANGKHQTALYEELLFHSGRPVLVVPWA +>tr|A0A1F2YR00|A0A1F2YR00_9PROT Uncharacterized protein OS=Alphaproteobacteria bacterium GWF2_58_20 GN=A2018_04675 PE=4 SV=1 +-AIRTILMHLTAEASAKARLEVGIALAHRFSAHLDIVFNVRPAhipaasagrgayvhymteainnahqMAGEIAHGIDTCCKG--LS-WSWGVVNeehSI---PLKARAN--TSDLLILPSAPMTYF-EDhFRWHLADCMAVDSACPTLVLPEG +>tr|A0A1P8S6Y8|A0A1P8S6Y8_9RHIZ Universal stress protein OS=Brucella sp. 09RB8910 GN=BKD02_11640 PE=4 SV=1 +-SYKTVVAYSRSEAELKRVLSAiGLLRQKVPDIHVIGLYAIPSPivyadpngfidpgmfelhdkqhkeLSERLKHVFEEEMRRQGIN-YEFRVTRsdtGTAADGVLASCL--GAELLIAGQPDPND--PATNDETADTIVFNASCPVLLVPYA +>tr|A0A231UUB6|A0A231UUB6_9RHIZ Uncharacterized protein OS=Notoacmeibacter marinus GN=B7H23_14785 PE=4 SV=1 +--MTTMMLDLTCPEALDPLMKVAAPLAKRLPGRIVGAHISPAFegvapiepfalsdayydevrsryerdigkRAKEVDQALTKALSAEDLQ-G--nlTHATagpNGIGAKLARLSR--NYDFVLALQKGKVN-----VAIPPEVLALDSGRPVLVVPEA +>tr|A0A0N9Z679|A0A0N9Z679_9ARCH Universal stress protein family protein OS=Thaumarchaeota archaeon MY3 GN=NMY3_03478 PE=4 SV=1 +PSFRKILVTHDGKDKSNKAINYAIYLSKLSGAEITILQIINdvkkqdnvnniEGDLIDSMEEKIKKIKHAGCEKVSYKFKTGNTIDEIVDEINEMNYDLVVLTSSHLSSWMESLF-SNTRKIISNIHTSVLI---- +>tr|A0A1M6CVU9|A0A1M6CVU9_9BACT Nucleotide-binding universal stress protein, UspA family OS=Tangfeifania diversioriginum GN=SAMN05444280_104106 PE=4 SV=1 +GEIKKIVIPVDISQSTKKKLLWATYFAKKYGATIKIVSSLSlnisakKSLAWKNAEKLKQILLERNIK-CDVDILkakGKEKHEVILDYIKKENPGLIILRTHQESNMAGTQIGKFVSEIVHGSQIPVFTVNR- +>tr|A0A0F4FN82|A0A0F4FN82_RHIRD Sensor histidine kinase KdpD OS=Rhizobium radiobacter GN=SY94_3784 PE=4 SV=1 +---DRVLVCLDHGRNGPGLVRYARRQADRLRAPWTALHLDTPRSQqlseaeKDRLAGTMRLAQQLGGE--TVTLPALDLTREIIAYANANNFTHIIIGRPRKSWWQRIFQRSLTHDLIDHAGdISVHVISGD +>tr|M3EWT7|M3EWT7_LEPIR Osmosensitive K+ channel His kinase sensor domain protein OS=Leptospira interrogans serovar Lora str. TE 1992 GN=LEP1GSC067_471 +---EKILVSIGSSPNSYSLLRYAKRLAYERNGELFAIYNQTRENLtkenLSQLEKNLSFARELGCE--ILYAADEDTAEAILRISGQKSITRVVIEKSDTNWWWRWnSTASK---LARIPSnFELCLVPYS +>tr|A0A0S8FUG6|A0A0S8FUG6_9BACT Uncharacterized protein OS=candidate division WOR_3 bacterium SM23_42 GN=AMJ83_02680 PE=4 SV=1 +-NFTRSLlVLTEDADQS--ILSVAVQFCKNSGSRLFVLFVIEPDRIsrlaslthqkvkvlhkkteedgWKLLYLIEDEAVENGV-WTSLHLEQGNLLQMTKHYVDAYEIDVLLIKKKEGSKR---IFVSCSVPVIGL----------- +>tr|A0A0S8JVW0|A0A0S8JVW0_9BACT Uncharacterized protein OS=candidate division WOR_3 bacterium SM1_77 GN=AMJ74_04610 PE=4 SV=1 +-KFDKVLlVLTDDADQS--IMPDAVQFCKNAGSRLFVLFVIEHNRIarlasltqqkvkvvlnkteeegWKLLYLVEDDAVENGV-WTSLHLEEGHLPQVANHYIESYGIDAMLVKRKDEFRR---IFSTCPVPIVGL----------- +>tr|A0A235BX87|A0A235BX87_9BACT Uncharacterized protein OS=candidate division WOR-3 bacterium JGI_Cruoil_03_51_56 GN=CH330_01575 PE=4 SV=1 +-MFDRILlFVEDK-NTPKETIIWTIALARQLGSRLIAVYIVDTNALpegkeqlslieekaWKILYEIEDDAFEQNI-KVSLLLEQGDPLEKLLTLCKSYEIQLVVLGSKSLPPL----------KLMER----------- +>tr|A0A1M3M9R3|A0A1M3M9R3_9BACT Uncharacterized protein OS=Paludibacter sp. 47-17 GN=BGP01_09530 PE=4 SV=1 +----RLLVAVGHTARSAELLVYASELAKTMHAsSIQAVYVENTYEl-tqrqRKELDYNARIAKQLGI-EFRIIS-NYDTVKGIAGFALQEHITHIVIDKPKTFNlLSLLRWGNFVINLIRNSEhIHVCIFGFD +>tr|F8E9Q2|F8E9Q2_FLESM Uncharacterized protein OS=Flexistipes sinusarabici (strain DSM 4947 / MAS 10) GN=Flexsi_0554 PE=3 SV=1 +KIINHILLCLDLSEIDEDIVHYSAVIAKSFSVEkITLTHIIQPSDLPkkdedslnevknsidemisiEFENFLKKELGENMIINIYTQIAEDEGLEIIVSNVEDMNVDMLVIGQK----YGEYRQKFHSRKPFAESDCDVLFVPEN +>tr|A7H942|A7H942_ANADF UspA domain protein OS=Anaeromyxobacter sp. (strain Fw109-5) GN=Anae109_1029 PE=4 SV=1 +---MNWIVGIDLRPLSHGALQFAAWLAANagagGADRFVPVHVLEEEHLRtmlryhhldevidAAREEAKRTLLREGRAewLGDLQIVQAvNAERSLEFVRAAAGAEAMVIGRAAAREGHRiVRLGRVARRLLRNLPSPVVVVPPD +>tr|A0A0C2D2E0|A0A0C2D2E0_9DELT Universal stress protein family protein OS=Enhygromyxa salina GN=DB30_03147 PE=4 SV=1 +---SKWAIGVELHEAHLGPVRFASALARTDEDLALGIHALPDLElLHplvnqaeakqmheKVASQITALMAQAGHNpaQVRVELVEDaEIERGLAEASVRLGVDALVIGRRANRDEDPiVRLGEVARKILRRLPVPVVVVPPD +>tr|A0A1F7MKP7|A0A1F7MKP7_9BACT Uncharacterized protein OS=Candidatus Rokubacteria bacterium RBG_16_73_20 GN=A2W08_01830 PE=4 SV=1 +---MKWILGLDLGPRSRGALQFARWIAEAthGSDDFVAVHVLDVDHLWgvlkyhhlseiieVANAAAHRELERAWPGgsLPVIEVRQAlTVEDGLAEARARHRAEGLVIGRAASTEGHHlVRLGRVARRVLRQLASPVVIAPPD +>tr|A0A0D8DB91|A0A0D8DB91_9GAMM Uncharacterized protein OS=Thalassomonas viridans GN=SG34_18885 PE=4 SV=1 +-EYQNIMAAVDLKKPpngefylDKEIIDTCVMLSEYLETSAHINHVYDPKGQElwqgnnlsllgfnmpsyispvppsqlesYHRTEFYRLIEHYAFDDTNIHLDTGIPGNRLTRNVIKHKIDLLIAGVRCHSGF----IGNTTGNIVDHVNCDILALKA- +>tr|A0A1E3G7W1|A0A1E3G7W1_9GAMM Uncharacterized protein OS=Piscirickettsia sp. Y2 GN=BGC07_01290 PE=4 SV=1 +MNYKKALFATDLRWKSFSAADQAVHVAQCLGIEdLTALYVIENRKFLSKVFYQEEEhlaycklseLASFSHI-RNYLIEEGDARKVVLEFINEHDIDLLFINAHCHSGFDR--LGSVGYALVNQAPCPVWLLP-- +>tr|U3QIX7|U3QIX7_RALPI Universal stress protein UspA OS=Ralstonia pickettii DTP0602 GN=N234_08495 PE=4 SV=1 +MDFRSILVDLSADAARSARIETAARAAAKFGGSVVGL-TATGTNlepfrgageeagqyaalaasqLHKLVAGHKEALDTLteqvsPDIPTRHIVIDAESGWALADEGR--FADLILPAPPSADADVPALLAGVAEYAMLNAGRPILLVPGA +>tr|D7A0E4|D7A0E4_STAND UspA domain protein OS=Starkeya novella (strain ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB 9113) GN=Snov_21 +MSIRTVLLHAAPDSGFNDRLAFAVALARQSGAAIKGLYTLYPAGvprvgralsiyvnelvreAKEKEGGLKAQFEQAtaaAGLAASWETIEGEVASSLREAVA--FADITVVSETPYGTVDDQLAATLPEHLAMACNGPVAVVPTG +>tr|K0N308|K0N308_DESTT Uncharacterized protein OS=Desulfobacula toluolica (strain DSM 7467 / Tol2) GN=TOL2_C03290 PE=4 SV=1 +-MKTNVLIGVSDSVIFREVLNRFIILPfDKAKLTITLVHVFRKATnseqllgnnyifrqierFANLLDLTKNILIQNGYQEEQVAVklietPYPTVSEGLIDQFKKGDYHMAVLGRKRMSKAEEFVLGDPCTKLIRYLEnTCVLIIKG- +>tr|A0A090LZQ2|A0A090LZQ2_OSTTA Universal stress protein A OS=Ostreococcus tauri GN=OT_ostta04g00015 PE=4 SV=1 +-PRRTILCPVNDDDISAAAVKWAVkNIYRDRRDTIHLLKILPPAHWSftyayaprptrerldktemkQFVRDEAKRAIQARFgrdlamrkVPYVIDLTTGQssnvaIGELICAISEAVQASVICMATHNRGAMRRFFVGSVANYCLRNSKVPVVMIRPE +>tr|A0A1V5KQD3|A0A1V5KQD3_9BACT Universal stress protein family protein OS=Verrucomicrobia bacterium ADurb.Bin474 GN=BWY82_01878 PE=3 SV=1 +--QGPLIACVDSSGYLEPVIQHAIWWNSQISaSGIVVANVSDLRCFDqpvvnelggalgvqpfqglvaelqriesmrveTIRSRATALVEASGGGiRWRFDNRMGVPADVIQPFQS--CALGVVLGKRGDGyGYASEHLGSNLDRILRSSQLPCLI---- +>tr|A0A1G8E6X9|A0A1G8E6X9_9BRAD Uncharacterized protein OS=Bradyrhizobium ottawaense GN=SAMN05444163_0660 PE=4 SV=1 +-DFGHILIAWSGSRESARALSESIPFLCLAEEVTVVVVTSEHPTEEEAVFgvDAVNHLRHHEIHAALHRIKssHKEVATQLMAEAERRKANLIVMGGYGHLPLQSGYRRFLRSR---SRSRPCRYGDP- +>tr|A0A0Q8B4A0|A0A0Q8B4A0_9RHIZ Uncharacterized protein OS=Rhizobium sp. Root564 GN=ASD74_20840 PE=4 SV=1 +--LGrSIAVLWKDDEETRSCLQKAALWLR-SAVTISILVER-AGDIEA-AVAFLGIVEPSPH-A---HIetGLVKHGKDFIEKAKILGADTLLMGAYRHGQFVEAVFGGDTKAVLDGTDLPVFLSH-- +>tr|A0A1R1SC18|A0A1R1SC18_9ACTN Stress-inducible protein OS=Streptomyces sparsogenes DSM 40356 GN=SPAR_29331 PE=4 SV=1 +-QLRPVLLGLDTATPDPALIEFAFEAAARRAVTLRVLHGWNPPYYYayamapdpavtetvaqadaaALAETLQPWRQKYPDVVVVAESRCCSPSLALIDASR--EASLVVLGRRIRRSSVGAHIGGVTHAVLHHATAPVAVVAHD +>tr|A0A0U4C8W9|A0A0U4C8W9_9BACT Uncharacterized protein OS=Hymenobacter sp. DG5B GN=AUC43_17660 PE=4 SV=1 +-MKPTFIVLTDLSPAAHRAAHLAALLAAPVGGQLHLLYLEQEPVFTpemgmvvipedfytqekLEADAALAELARTLPVPATASACRGSLHDVLGELISERQPQLLVMALYEEHDLLDALLLDQALPVLRDSGLPVLLVPEC +>tr|W8F4L1|W8F4L1_9BACT Uncharacterized protein OS=Hymenobacter swuensis DY53 GN=Hsw_1931 PE=4 SV=1 +-MKPSLVVLTDFSPAAERARAYAAALAGPLGAELHLVHVVAPLPPIptesgvmlmpptdaryvQETRQSLAQVAAGLPVSATAELLETTWDAAIEQAIEQYRPQLIVAGLSATHGWLDEWLSNRTRSLAHQTGCPLLLVPES +>tr|A0A142HKN7|A0A142HKN7_9BACT Uncharacterized protein OS=Hymenobacter sp. PAMC 26554 GN=A0257_21670 PE=4 SV=1 +-MNPSLLVLANVPEAAPHMARYAAALGQPLGLRLALLHCGLCAPLPepksmgeeaalpsrneVQTLAALRALARRLPVPAEVAEAGGQLEDDVAAAANRYQPLLVAMGLGPRQHLLDELLRTQVLPVLRATGRPVLLVPAA +>tr|G6EK59|G6EK59_9SPHN Universal stress protein, UspA OS=Novosphingobium pentaromativorans US6-1 GN=NSU_4730 PE=4 SV=1 +-GFQRILIAWKDCREARLALTAALPFFCRAH-TIMIVGLGEE-APTGCLEAVQGYLAAHDIDAKYFHAAapKGNGARWIAEFAEREGYDLLVTGARARGRWKERIFGGMTEDL-RAMNLNWLLAN-- +>tr|A0LLQ4|A0LLQ4_SYNFM UspA domain protein OS=Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) GN=Sfum_2678 PE=3 SV=1 +NETGKVLIAMEDAPESRELTAYAAEfVAPSRRMRFTFLHLMPPVPPTfwdnghilgsaerkdrqsriekwrsewmdrvsKFMSDGKELLQRQGTPgtNLDTLVLptKLGIARDLLNEIAEHQFQMVIMGKKSFHERKPFLMGSHASKVMQNVKCVVL----- +>tr|A0A1F6GAF6|A0A1F6GAF6_9PROT Uncharacterized protein OS=Candidatus Lambdaproteobacteria bacterium RIFOXYD2_FULL_50_16 GN=A2527_07940 PE=4 SV=1 +-MKRQILVPLDSSAVGREVIHLADQWAHLFDAELVFMQVNPVLRDVADQDLLESVILSERVTaPYRAIASYGNPSQEIIEQEKVVDPWIVMMAAHSHSMMARILLGSNTDYVVNQCKSNLFVYKRS +>tr|A0A1W9S094|A0A1W9S094_9BACT Uncharacterized protein (Fragment) OS=Candidatus Coatesbacteria bacterium 4484_99 GN=B6D57_04000 PE=4 SV=1 +EKVKRIVYAAEDSADAKYALSILPAFQDEFNVHIVALHVI-KGSPQvfehlSGQIFLDELLKDCPIKIERKIIVAESVEEGIINFVE--PTDLLVMGLGSSSFLERILFSSVSEEVSERLEGPVIMIS-- +>tr|D0LX45|D0LX45_HALO1 Amino acid permease-associated region OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_3585 PE=4 SV=1 +ADARRVLVPIGGrGGQHEMRARLLGSIVRTAPREVVFLQVVAEGAGADEIEQARRQAESLvrwnlTGQHEVAVVAASDVATAVVEAAA--NCDLLVMGLQAErnpfgVGRGRAAFGELSLEIARRASCATILLSG- +>tr|A0A0P8AKV1|A0A0P8AKV1_9BACT APC superfamily amino acid-polyamine transporter OS=Bacteroidetes bacterium HLUCCA01 GN=HLUCCA01_04845 PE=4 SV=1 +SQARKILIPVAGfDKHDLLRARIAASIWRSYQPEITFQQLVPAGVSKKELRTQRRLLHRFaeeiiPTGFKTSIKQSTDIPATLVHEVS--QHDLVIIGLGR-LLPGDKAFGPIPMDIIKKTNTAAIFISH- +>tr|Q7UFY5|Q7UFY5_RHOBA Cationic amino acid transporter (Cat-1) OS=Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1) GN=RB8254 PE=4 SV=1 +DQSQQILVPVGGrGGHDYLLTRLLSSLSREQQRQVKFLRVIPTDTLRADQKRIRKELDRTtrvnaGRVCEREVVRSNDPVKTIADRAG--TAGLIILGAQR-LGPRQKLFGDFTRKVALESDCPVIIISR- +>tr|A0A1V4QQ77|A0A1V4QQ77_9BACT Uncharacterized protein OS=Planctomycetales bacterium 4484_113 GN=B1H03_06510 PE=4 SV=1 +PVVKRVLVPVANPVQARLSMAVAAAVAGqRSDMQIDLVNLVPVGTPAEVREQRLQELHDRmlrvrgelppdsplEEARDQLLVegttynlvqyEAESVVKKLAALST--NYDAMVIGGTSGr-VWRSHVFGRIPRYVAEHAKCPVVLVKM- +>tr|A0A0E3ZFB7|A0A0E3ZFB7_9BACT Uncharacterized protein OS=Pontibacter korlensis GN=PKOR_10120 PE=3 SV=1 +HSLRRILYATDFDKTDAQALATLLQLFEPFNPEVLCAHIGTEGSETEdshKMEQLQARLYTaLPNHNLQFVILPsSdDVADTLQEFVEREQLELIAINNHQRTLFSSIFKPSLSKKLVLEAHVPMLIFHSP +>tr|A0A1V6HFL4|A0A1V6HFL4_9BACT Uncharacterized protein OS=Bacteroidetes bacterium ADurb.Bin041 GN=BWX63_01536 PE=3 SV=1 +HGFDNMLYATDFNDEDVYDLQRLIDLISNYNPVIHCLHINFDADHSAdieKMESLKSHFREkSYYGKLIFKVIEDvDFLQGINNYVSENKIDIIAIVNHRRGFLKRLFTKDHTRELLFHSDLPLKIFPGV +>tr|A0A1Q9TJM3|A0A1Q9TJM3_9MICO Uncharacterized protein OS=Kytococcus sp. CUA-901 GN=BJF82_04635 PE=4 SV=1 +-PVTSLLFVLDAAPGHHVAREYVVDLAVHRSATVHLVYVALESTRttpmavnpdqrrrlaqeaQAAMDDEVTRLADLGVTDVQTHLRAGDTASHVLGLADDLGVDLVVIGDQADSRVLRALVGErPATRLARRAPCSVLVAKEG +>tr|A0A1M3ICR5|A0A1M3ICR5_9BACT Uncharacterized protein OS=Bacteroidetes bacterium 43-93 GN=BGO70_14415 PE=3 SV=1 +----KVLIAVDYSQQTERVLEAAKVLigARVPQPDVTVVYIIDEMWLstatggegevfntlRDDSKKINELAIKHLGNNVVYLEEYGIPTVKINEVLDSTPHDLLVFGMKGRSALADVFMGSMASHLLHRVKTPMLVVP-- +>tr|A0A017HER8|A0A017HER8_9RHOB Uncharacterized protein OS=Loktanella hongkongensis DSM 17492 GN=Lokhon_01615 PE=4 SV=1 +KHMKTIVAATDFSKAGNQAVLRGAAIAAHTGGRLHIFHAANFRIAAEqkahfnalvegYFDTLRARIQCRYGSSLQVSHTYSGDWQDIYAILKRKKANLLVAGQHVHPNGIDMFHGTFVERLTADCPVPVLV---- +>tr|W5WFI6|W5WFI6_9PSEU Uncharacterized protein OS=Kutzneria albida DSM 43870 GN=KALB_3565 PE=4 SV=1 +REVGPITVGTDGSYWGGLALQWAARYACTLGTKLRVLRPGTNAELPADVPLDLGLthtMHLYPLLPVICTPITVDPLAEFAEAST--GSELLVLGCRGHLHRCTIGLGSLVLPTVSTAHCDVLVVRG- +>tr|A0A166RIC4|A0A166RIC4_9EURY Uncharacterized protein OS=Haladaptatus sp. R4 GN=A4G99_15750 PE=4 SV=1 +---RNVLVHLTGSEIDQCLIREAGTYVTGTGGKLVLVNTMAPNEFMErqqahaqidhlptyticqaeescrqhALKRGRQALVAFGI-DYTAVGMVGRETDSLLTTAQQYDCGHLFLGDQQQSLLRRFTALSFSQVITRKFDGLVTVLRS- +>tr|A0A1G7RID8|A0A1G7RID8_9EURY Universal stress protein family protein OS=Halorubrum xinjiangense GN=SAMN04488067_11564 PE=4 SV=1 +---NNILVAVDSTDANGYVMERAIESARLEESTLVVAHVMSTAQFDDhlgaigtipelrkdgatftvdqareraravATRAARAAVGDLDI-AYVTVGAVGQVDATLLEIADQHDCGTIMLAEQRSWWRRRLGWGD--KRLARSFEGRVIRVPR- +>tr|A0A101DZK8|A0A101DZK8_ARCFL Uncharacterized protein OS=Archaeoglobus fulgidus GN=XD40_1966 PE=4 SV=1 +----KVLLIVDDSELSDKATECAIDLHLsGLKSKIYVFYIKDEEPVAfpseglerkkyapmvskaeKVIIQTTEKLKDAGIDYEVLGYHIGIADEEIKRIEETFKPDIIVYGAEKKSRFRKLIQGGCEENIVFETDAPVIVVK-- +>tr|O30112|O30112_ARCFU Uncharacterized protein OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) GN=AF_0125 PE +----RVILVIDDTDCGRVAAERLVFMARaGFRGDVFVVFGKDIEISPiasyekemkiytslrvkasKFVEFYRERLEEAGLEVKQVKIILGNVSEEVLRLEKLLNPDLIVFGMEKRGFLKRLLRGDPYKEIIYETKAPVMVCK-- +>tr|D2RFF7|D2RFF7_ARCPA Uncharacterized protein OS=Archaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18) GN=Arcpr_1807 PE=4 SV=1 +----DVLVVVDDRWN--RVPESLK-NLGkRFKAKLHLLFVRNLQITPevltelekkysslkekalKKLQSLAEELKSYGFGTDIVGVHYGIAHERILRESERIKPDYILVRARRRPRLWRILGDYYYDDLFRSSKIPVLVGR-- +>tr|A0A1G0CM58|A0A1G0CM58_9FLAO Uncharacterized protein OS=Fluviicola sp. RIFCSPHIGHO2_12_FULL_43_24 GN=A3E30_02200 PE=3 SV=1 +-EIKNIVVPIDLTKESLQIVSPAGDLARIFDATVHVIGERHNDEGLSQQTKnrvllIRNKYDEKGAKcEVHLLKNGGSYSKKIMQYVSEVGVNVIAIAYHSESLLP--QFDSFAQSLITNDLKlPCMILAA- +>tr|A0A1Q3ZEK1|A0A1Q3ZEK1_9BACT Uncharacterized protein OS=Flavobacteriia bacterium 40-80 GN=BGO87_08685 PE=4 SV=1 +-AIKHIAVPIDISSESLQITNIAADLGKMLNAKLSVIYEPVHDFTLNNRMNirlgiVRESYDNKGVDyEISELKGSGSSLKKINHFMADNECDLVAIAYFSNALFP--QFDTFAQNLITNKQKlPCLIVSA- +>tr|M1PR57|M1PR57_DESSD Universal stress protein UspA-like protein OS=Desulfocapsa sulfexigens (strain DSM 10523 / SB164P1) GN=UWK_02326 PE=3 SV=1 +---KKFLVPVDGSVNSLMAIDHLCHIFAeRTDIEICLFHCtaifgkeihCKPELFYKKWGKDwsdthlsgtdclfngpQQLLLNAGIPEKQIQILPEstdiEEAHSIIREAKKRDCGTIVMGRRG-KATSKGLFGGVSDRAIKHFQ--------- +>tr|A0A0U5J571|A0A0U5J571_9GAMM UspA domain protein OS=Thiocapsa sp. KS1 GN=THIOKS11770032 PE=4 SV=1 +-----LHFAYDGSINGDWVSHYAVQLASALHdRTLRLIHVRSEQILPAMLEDKLGRILRECAHqRVRLIkeilpPAEHTLETAIRSAVPAGPEHFLLCGTPARAPGHGALRETIAGRLLRSGHCNILAVR-- +>tr|A0A0A2HTT4|A0A0A2HTT4_9DELT Uncharacterized protein OS=Desulfobulbus sp. Tol-SR GN=JT06_10255 PE=4 SV=1 +-----IYLAYDGSINADWVSRYAIRIAATFHnRRIILIHILDHSASRRRIDEKIAAIARECEVhGIECRsvihDLDRDVFSSLLRLIPAGDNSYCLCGARIASRGRGFLAGTVSERLLRSRLFNVMAIR-- +>tr|W0F7U1|W0F7U1_9BACT Uncharacterized protein OS=Niabella soli DSM 19437 GN=NIASO_09330 PE=4 SV=1 +--PEHIIGATDGSAESMHALTQFCKMFPQYsALPAKFVYVKNEHNKKIPDRRLLKEYVSLHFKEAEILKLHWDHQKLFTTWLGCYKNALVVTGAFGRSALSNLLQKSFAAQVIREQAARVFIAH-- +>tr|A0A1A9I2B8|A0A1A9I2B8_9BACT Uncharacterized protein OS=Niabella sp. BS26 GN=A8C56_07420 PE=4 SV=1 +--PERIIAAYDGTDESMHAIIQFCKTLPLFqSLPAEFVYIKNENNDRIPNQELLQEYINAHFENAAVLKLHWEPGRLLTRWMECHRNPLLITGAFGRSALSNLLHKSFAELIVSKTGCFVFIAR-- +>tr|A0A0N0UYA2|A0A0N0UYA2_9BACT Uncharacterized protein OS=bacterium 336/3 GN=AD998_09710 PE=3 SV=1 +-NIKHIVFASEFEQEPDKVMQELNDWQSITGAKVTLLKVNHPSFTLNreemesslNEFALRNHIKNYGVD----AYTDIDPTHGIIHYAEHNKADLIFVGTDFYKGLLERLWHRRTQVaeeVATHTAIPVVSYH-- +>tr|A0A136PAP3|A0A136PAP3_9BACT Stress protein UspA-like protein (Fragment) OS=Chlorobi bacterium OLB5 GN=UZ05_CHB002000538 PE=3 SV=1 +-EFRKIVFATDLEHKARKVINQAWAFLKMYNAKIDILRINTLKDSIRstyAIGQMRNISKKYNaefdFV----LAEAKTPEEGINEYCVKTKADLLVIGVHRKKGFKRLFTDRISESitrT-------------- +>tr|A0A147JXQ8|A0A147JXQ8_9EURY Uncharacterized protein OS=Hadesarchaea archaeon YNP_45 GN=APZ16_02575 PE=4 SV=1 +-MFKTMVLCVTEATP-EEVVKVAIRLCSK-ETKIYALHVvrllseFSKKEALERFSWVIDAFERAGLKSQLEIIESTDVGKAIVSFAKKNACDVIVTGTIPRKGLLGAFTESISDYVIKYAPCTVILVRKS +>tr|A0A1H5VWQ1|A0A1H5VWQ1_9BACT Nucleotide-binding universal stress protein, UspA family OS=Bryocella elongata GN=SAMN05421819_1348 PE=4 SV=1 +--PRHILHPVSFEGGYEVAVSQVSELAKAAEAHLTLLHVLDDSPENKvnpgrILQWAhhalgqLATASGLLPEHVHLQVVEGRVADQVVRIARQAAADWIVFATDEQTS-ASLLNESRSFRVMAEAECPVMLLRS- +>tr|A0A1Q4GFY7|A0A1Q4GFY7_9PROT Uncharacterized protein OS=Thiobacillus sp. 63-78 GN=BGP20_09345 PE=3 SV=1 +-GVAVDL-TERSAATIRKAGELApnatTCLLHALqAPNHERLrqlgasdeHIKRSRSEFydravreigkliadrqderisrVVELDYPPAMIRRWTEK--------------------LHFDLIVMGKRGGRLGS------VVRHVLHNSASDILVVG-- +>tr|A0A0S8F6W2|A0A0S8F6W2_9GAMM Uncharacterized protein OS=Thiotrichales bacterium SG8_50 GN=AMS22_00710 PE=4 SV=1 +-MSETVLTIIELDNYPEEVVARAAWLARLMNCDLELLLCDPTTSFLsevfiissevrdlakdieeaqkTTLLDLAKTAESSGL-KVITHISHERPVaDGIISRAMDLEPMFVVKGTHYHSPAERATFADTDWQLMKKLDYPLWFVKP- +>tr|R9AHQ6|R9AHQ6_WALI9 Uncharacterized protein OS=Wallemia ichthyophaga (strain EXF-994 / CBS 113033) GN=J056_003901 PE=4 SV=1 +-PSRKILLAFNGTEEAIHTLNYLKNKILRNGDHLFIAHILEMPADDQqthesnliqlkqirdhvldNLRAISNDILHSNLHITTTLLVinHADAKIAICRIADHHAVDLIVVGRRRRDEGGGGIPGACSTYILKQSRNPVLIVNKS +>tr|A0A1B7UQT5|A0A1B7UQT5_9GAMM Histidine kinase OS=Rheinheimera sp. SA_1 GN=A5320_05625 PE=4 SV=1 +---DKLLVLISNQRDHEYLIRIGRRVAEKRQMPWLVVWVDTGKlqyqSMQQRLQSAFALARELGAQ--TDILRGPSTLQMVLPYIVEHRINSVLVGAGTRRPWQ-PWRKPLYQQLINSgLPLEVSVYRAD +>tr|W1FW48|W1FW48_ECOLX Universal stress protein F OS=Escherichia coli ISC11 PE=4 SV=1 +-MYRSILVPIDISETdlTRHVVPQVQAHA--KTAKVHFLAVIPTVPFYaslglaystefpdrsGLQAKASEKLEEIikqfniPAGRSQTHVVLRPAEGSDPQVGRGGGR--------------------------------------- +>tr|A0A0Q2UM69|A0A0Q2UM69_9RHOB Uncharacterized protein OS=Loktanella sp. 5RATIMAR09 GN=AN191_16685 PE=4 SV=1 +----MISILTDLHPRSDRVLDRSALIADELSSDLDIVHAINPDSdfaeatakleapqFSDDDGNLRTALAIKNPIRMQWVGLRGAAPDSLVTYIADKRPDLIIVGTGREFTLSKLAIGSTVDRIVARASPAILIVK-- +>tr|A0A1Q7JC59|A0A1Q7JC59_9BACT Uncharacterized protein OS=Gemmatimonadetes bacterium 13_1_40CM_4_69_8 GN=AUH78_13495 PE=4 SV=1 +SPMQSCAVAFDGGDTSRRALDLAARFASIFESTVHVIHATPDHEAGVRVVGTAEAVLSMLGVSFVTHIEGGSPGEVVARVIARTKCDALFAGAHleRRSGRPSQPVVSHAEEILRHTDIPVVIQP-- +>tr|A0A1Q6WTY4|A0A1Q6WTY4_9BACT Uncharacterized protein OS=Gemmatimonadetes bacterium 13_2_20CM_70_9 GN=AUH07_00350 PE=4 SV=1 +SPMQSCAVAFDGRDTSRRALELAMQFASVVEGTIHLIYATDDREAGLKVVGVAEATLSMQRVAFVTHVEPGKPGEVVARVIKRTHCDALFAGAHmtHQQGRPSAVVVSHAEEILRHTDIPVVIQP-- +>tr|A0A133VR25|A0A133VR25_9EURY Uncharacterized protein OS=candidate divison MSBL1 archaeon SCGC-AAA382M17 GN=AKJ55_00305 PE=4 SV=1 +---KRILIPVGYKGYdyTKR-LSVTAKIIKETGAECVLTHVNQEEESeeeaEEILQSSKELMRNMGVNSETKILRNEDISEALIEESS--DYDLIVLGPTNEYVFSRYLFGWMTDEIVNNVECSALVFK-- +>tr|A0A151AA93|A0A151AA93_9EURY Putative fructoselysine transporter OS=Halalkalicoccus paucihalophilus GN=HAPAU_36010 PE=4 SV=1 +----QVVVAISNPETAKRLVTFGSRIARHHNGEVLLTTVVTVPVQtpleeganyitnqRELLAEAMRYVP-EDIPAHRVVTIGRNVGRSIVNLAQERDSELVILGWRGRSKPTkPPILGTTIDYIVENTPCDLVIAKTE +>tr|I0A231|I0A231_FERFK Cationic amino acid transporter (Cat-1) OS=Fervidicoccus fontis (strain DSM 19380 / JCM 18336 / VKM B-2539 / Kam940) GN=FFONT_1 +----RIMVLLP-PEIRTNLIQLASDIAKAKNGEINLLKIIKTPYQlsvkdyrneavkkdVRSLKDIIDHLNETGIHARYSIKAARSKTEAIIASIDEERIDLLIMSAEDAMKLN---------SVMRLSTCDILIVNTE +>tr|A0A075FWJ2|A0A075FWJ2_9ARCH Cationic amino acid transporter OS=uncultured marine thaumarchaeote AD1000_72_F04 PE=4 SV=1 +----RIMIVFD-KRNATKFYKIAKAISEQNDGEITVLNIVNVPRQtplslshgigdngLKAIEEFKRAIP-GSLRNRFLVRLAHDPTEAILSTAEEQDINTMLVDF--SFLRNNR-------KLLSLTTCDIIGIRLR +>tr|A0A1J4WK74|A0A1J4WK74_9BACT Uncharacterized protein OS=Parcubacteria group bacterium CG1_02_39_15 GN=AUJ31_01070 PE=4 SV=1 +----RILLPIYPDTNWKDLLNLALVFAKQKDAEIFILSVRQIPLPlpliaeeeeieddKRFLEEALNLCKDCGVNVHAVLMTSRSISEAIISMIQREKPSLLLMGWKGYARLTkagQKIFGRDLDIILREVNCDLIVTRLE +>tr|A0A1G1ZN13|A0A1G1ZN13_9BACT Uncharacterized protein OS=Candidatus Harrisonbacteria bacterium RIFCSPLOWO2_01_FULL_44_18 GN=A3A16_01580 PE=4 SV=1 +----RILLPIA-PHLSleeiKNLAENAFVLTSKYDGELVIVTIHEIAAAlplnpamieegllqreKEIFAQLhqwveeynkKTGPEVKNINFHSLILIGRDIVDVLLDVIKMEDCDLLALNWTGYVEGQDAILSRKIDRILRESKCDLLVVKNP +>tr|A0A1G2PFL6|A0A1G2PFL6_9BACT Uncharacterized protein OS=Candidatus Terrybacteria bacterium RIFCSPHIGHO2_01_FULL_43_35 GN=A2828_04165 PE=4 SV=1 +----RIVVPIVGTASLheaaLRLEVVKAMAKRYLPATIYVIGIHNVPPSrtfesvikhpngqesgeldhehsfvHEVAKKIKESMP-DDVDVDASIRLarSGGEADAILNVVERYHADLLVLGWRGWTKTQGQRLGSTLDPILYRHSCDMIIVKQG +>tr|A0A1F3Y6S1|A0A1F3Y6S1_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium RIFOXYD1_FULL_55_31 GN=A2603_16235 PE=3 SV=1 +RPIRRILFPSDFRSDSKRVLDRVIGLAGQLNAKITIFHAATmprageiplskpaavrfedleiPPAWRDYHEQRRQEAEAFTDHIRVSRVdaealfdSSGQPVGEVIQlIAAAEDVDLIAISARS-GPISTYFKGRITQRLIRQAHCPVWVLHEN +>tr|U2YNY7|U2YNY7_9SPHN Uncharacterized protein OS=Novosphingobium tardaugens NBRC 16725 GN=NT2_10_00550 PE=4 SV=1 +--MKSIIIHIGLDPEVETRYQAAVDVVQAFQGHLTCVQTATpVDAYmpvdpfggaafmadsyerakqaeEETRVRLEERLRTEGI-SWDWHCHAGAPARLLANHSW--LSDLIVVSAPPANWAARLGTPPVAADVAVNAHAPVLVMPEG +>tr|Q2GAV5|Q2GAV5_NOVAD UspA OS=Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CIP 105152 / NBRC 16084 / F199) GN=Saro_0571 PE=3 SV= +--MRSILCPVDASETLDDRVETALALARATKGHVTF-QISTpFAQMavwepfggatisaaaiadaregdEKLQRQLDARMASQDV-PFDVTIEDSGHVEAAAAAAR--FADIVVDTLDHP----------SLEELVLGLRSPVLAVPRG +>tr|Q0FZV1|Q0FZV1_9RHIZ Uncharacterized protein OS=Fulvimarina pelagi HTCC2506 GN=FP2506_04656 PE=4 SV=1 +RMYTRILVPIDLDHRekLEKAMKTAADLAKHYQASIVYVGVGSSAPSgsahtpeeykKAVERFAKSQSDTYGVSATGEAVIVHDPSveldRAILKAIERNGSDLVVMATHV-PGIPDHFYAAHGAKVASRASVSVMLVR-- +>tr|A0A1H8EIT7|A0A1H8EIT7_9RHOB Nucleotide-binding universal stress protein, UspA family OS=Pseudorhodobacter antarcticus GN=SAMN05216227_10093 PE=4 SV=1 +SMYKHIMVPVDLAHIdkSETAFVIVADLAKLYDAIVTYVAITSNVPGaiahnpeefaHKLADFAKAQSDQRGHRTAAHSVVSSDPTvdldKKLAGTVDELGADLIVMATHI-PNMADMLLPSHGGALARHTGASVFLVR-- +>tr|A0A1E7QGD3|A0A1E7QGD3_9FLAO Universal stress protein OS=Salegentibacter salarius GN=BHS39_10245 PE=3 SV=1 +--MKNLLVAIDRRQDAEQLMTQAIKIAKLTDAKIWIMHVTEADPDDflareagpqyvyekrakerknasLEIQKWVEEVKEKYSIDIEGLVINGEVTKSIKNIVDERNIDLVVAGHKKKSLLYGLFTANKKKDLIDDLKVPLLAIP-- +>tr|A0A1I7GG94|A0A1I7GG94_9BACT Nucleotide-binding universal stress protein, UspA family OS=Pontibacter akesuensis GN=SAMN04487941_0989 PE=4 SV=1 +---KRVLVPVKFDKAGKKLLRYAGHLANALGAELLLLQNSHTNELtftqqssflqqlrtFSMRILGEEQMSGAKQVPFQCVVRPGQLRECINVIIREYAIDMVLMETCVLHQEEGHNDPDNAAAIMELVKCPVMVVPCT +>tr|I7A1Y7|I7A1Y7_MELRP Putative universal stress protein OS=Melioribacter roseus (strain JCM 17771 / P3M-2) GN=MROS_2021 PE=4 SV=1 +-KFNKICVDVDYTPLNEIAVKKAYKLALLENTEeFILVREFQVPGLAitvsdggdsedteskrliwqkeeeMKLKLFAEELNLTEIK-PKLVCRYGREGWELQQYVRESGSDLLVVALPPNkLKFFDRIFKHDLEFIFSQLPCSLLIIR-- +>tr|A0A090WQW1|A0A090WQW1_9FLAO Uncharacterized protein OS=Algibacter lectus GN=JCM19274_1067 PE=4 SV=1 +-PCQHIVVNGLKDPKTESTITAAFYVANQLKAKkVTIVEEINEEQVTvkvdddkslrratiikeriklrenSRIKEIISHIPVectTEKS-IKLQPIFGKKGYSIGHYAQIMRADLLVMNAPTKMTFWDRLFPHDIEHILTELPTDVLILQ-- +>tr|A0A0F2N8L5|A0A0F2N8L5_9DELT Uncharacterized protein OS=Desulfobulbaceae bacterium BRH_c16a GN=VR65_24145 PE=4 SV=1 +-TFKRIMVDCVDHPKTLHTLDTAFYFGSQTGAGeICVVGEVDPAGLVmalsgdttqerdlvkeqlvieaeENIKEKIASCNTRGMH-IQNSVLFGRPGFMIRKFAEDRRANLLVINSPDSrYGLMDRIFTHDMEYILEHLPCHILIVH-- +>tr|C0BIZ3|C0BIZ3_FLABM Uncharacterized protein OS=Flavobacteria bacterium (strain MS024-2A) GN=Flav2ADRAFT_0805 PE=4 SV=1 +-PCKHIVVNGFDSPQTHETVEAAFYVGTSLNTEkITLVEEISESRVAiavnddrslrkatlrkekidreekLRVTDIVEKIPAtkrDGLK-WETQSIFGRRGYSIGHYARVVRADLLVMNAQEERRFYHRFFPRDLEHILAELPTDVLIIH-- +>tr|A0A1M7ZGM6|A0A1M7ZGM6_9BACT Nucleotide-binding universal stress protein, UspA family OS=Algoriphagus zhangzhouensis GN=SAMN04488108_2991 PE=3 SV=1 +-EFSKVVINGTQLEITPVVIEQGLEFSKTVKADqVSILNEIKMYGLQmgtasedsedeiaqtrrqlvqneiDYVEQILQKLDKGNLR-INIKVTGGKWAVELARFCEKTDADLLVVGDE-RkLNFFDRIFPHDLEELLSTLPCNLLIVK-- +>tr|A0A1Q7S457|A0A1Q7S457_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium 13_1_20CM_4_55_9 GN=AUG90_00050 PE=4 SV=1 +-PLRRIVFVANYSDHAQRAFQQALKLAAAESSErLYAVRVYTTFDEVrattfvdngdgtprprtfdeedAALEKFVLAAGETEVP-IEARCIRGNTGFAASDFIDSVEADLLVVPVHKSe--TSAERLPNHLAWIADVIPCNLWLIR-- +>tr|M0CQ39|M0CQ39_9EURY UspA domain-containing protein OS=Haloterrigena salina JCM 13891 GN=C477_00985 PE=4 SV=1 +-MDRSILVPYDGSRRSQSALRYAADVF--DGETITALHVLDPFATipdsekqvRERYERAQDVLETVPAVaderstTISSEFVYGHAIHAILRYADLYTIDRIVIDGSYRADTADAPLGNVSEALVRRTRAPITVLRSA +>tr|A9W3K8|A9W3K8_METEP UspA domain protein OS=Methylobacterium extorquens (strain PA1) GN=Mext_1765 PE=4 SV=1 +PAMKTLLVPVTLHDALPSVFATAVLVARRFGSLIEGVALRPALAEYvpvdmvggmtwlrdeeadqAEAQDAGQRFVaameaaglprrepgascapdavPNAGPRYRWQPDVPPGDAFLGQYAR--LFSATVVGRPGADDGSP--RMTTFETALFESGRPILLAPPA +>tr|R5QNR7|R5QNR7_9PROT Universal stress protein UspA and related nucleotide-binding protein OS=Acetobacter sp. CAG:977 GN=BN820_01398 PE=3 SV=1 +SGFKEILVCSDATENIEATLETALLAARRFNSHIDAVHIHKEPTCVlpvpvvtsdmagfvvndvvtaeetalaETADKTRRIFEkfiekedirpqaepdlNSNEVTAEFRELYGSADEILSWASR--VSDLTVLPRPDTEALSEDA-FEMMNAVLMESGSAVLVSPLT +>tr|B8IKU8|B8IKU8_METNO UspA domain protein OS=Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060) GN=Mnod_1305 PE=3 SV=1 +MPMRCLLVPTGPDTDPRPRLDLALRLSDRLKAHIALTILCPSAEDVlasipevaiaagvtrerleqetrEAIEAARIAFDawcagadvvnrpaddiCPGLEDASFTVRLGPIDASLARAGR--LSDLILVDRPDWSDPFAAV---AFDTAVFATGRPTLVVPPA +>tr|A0A1B9Z0S7|A0A1B9Z0S7_9BRAD Universal stress protein UspA OS=Bradyrhizobium sp. LMTR 3 GN=LMTR3_15715 PE=4 SV=1 +-MFRNILVHIPSERPVRPVIDVAVSLTIARRSHLDAVAIGYESMGAagmiaegggaavaavmgaeqeraqERANAAIGVFEieaklani--AYGIRTFTAIPAEAGQTIGALSR--LYDMTIVLQPDPVKASY--DNEIPQQILFNSGGPMLMVPYI +>tr|A0A1N7MBT2|A0A1N7MBT2_9PROT Universal stress protein family protein OS=Insolitispirillum peregrinum GN=SAMN05421779_10410 PE=4 SV=1 +TGVKTLLAVVPDVEGGLPTLETACIIGRDLACHVRVLHVRPDPSSAlplmgeamsgamidqmmatcekegtARAVRVRGIFDqliarydipqtdeppGPSEMSAAYIELIGQEDEAAVSYGR--MADVVVIGRPQDG-DDEPALQATLNAVLMETGRPVIVAPRQ +>tr|A0A1N6L8T9|A0A1N6L8T9_9BRAD Nucleotide-binding universal stress protein, UspA family OS=Bradyrhizobium erythrophlei GN=SAMN05443247_10475 PE=4 SV=1 +MSIKRILVPLPGSANHTGQIETALSAAKALGAHVQALFISQPPPVTrapggltvtemgrtvtapsinwhaeereRTARDAREVFVqacarvgipmlsandePGSPLAASWRKAEGSYVEIAVQRAA--AFDLMVAASA--T--VMESLVAIAEQSLLRTRRPVLLAPAR +>tr|A0A1U9KTZ2|A0A1U9KTZ2_9PROT Universal stress protein UspA OS=Neoasaia chiangmaiensis GN=A0U93_04155 PE=3 SV=1 +NDIRNILLPLNGNGDIDAALQLGLLYAKHFKAHLSAVTIGDDPNETaalageglsgsminemmaaaehesqRRLLQVHLKFDnfvrehnvanrrnalpsdlpPNGQVSASLETLTGSEHEAVTWRAR--LADMTLMPHLAKNDDAR--ASETLHAVLFDSGRPLVIAPPK +>tr|A0A1X7DKL8|A0A1X7DKL8_9PROT Nucleotide-binding universal stress protein, UspA family OS=Azospirillum oryzae GN=SAMN02982917_0648 PE=3 SV=1 +-MYRKILVPLSNAAgSMDAALDAALFIGRVFGARVEVLYARPSPENLilvlgkgfagtmlenamrevqakiaRDCQAAHERMQghlrqaaaAGRDPEIVWREVDGPADKTIATEGR--FADLLLFAKPKHDGVTDNVWRSMFDAALFGTARPVILTPFT +>tr|A0A1Y5EEI4|A0A1Y5EEI4_9PROT Uncharacterized protein OS=Alphaproteobacteria bacterium 46_93_T64 GN=A9Q83_02710 PE=3 SV=1 +MSIKAILVPVYGSDtgCDSSALNSALTFSERFSGHVDALHVKRDPRAAasfvgegmttsmiesvidmaekdgqRREKSAALLFNelcsshgtviagdekisASTASTARFIMRSGNQEDLLPEYGR--MFDVIVVCKKTK--ERSSDNDHVINSAILETGCPVLVVNDA +>tr|A0A1J4XZE6|A0A1J4XZE6_9BACT Uncharacterized protein OS=Candidatus Marinimicrobia bacterium CG1_02_48_14 GN=AUJ47_03500 PE=3 SV=1 +----KLLLCVDDSNRTRLAVKTAAVVAAALNLEVVVLTVSKTTRFgpgyTAAHNWAMDYLAQKEI-KHTGIKRTGDPVTTFINEQG--TDKIIVMGSSSGS---------------------------- +>tr|A0A1Z9NGG4|A0A1Z9NGG4_9BACT Uncharacterized protein OS=bacterium TMED217 GN=CBD77_03740 PE=4 SV=1 +----RVLLPINNEDGSMKAAKYGIRVALAYDIGIDILTVSNDQKSindeNKQVDKIKKIIRRSGV-EYVHEKEQGNTVEKVIEKAG--DDKIIVMRSSDMS---------------------------- +>tr|A0A1M3MSW4|A0A1M3MSW4_9DELT Uncharacterized protein OS=Myxococcales bacterium 68-20 GN=BGO98_23735 PE=3 SV=1 +RPYRHLVVAIDAASDLRRLLEAAKIVA--PGAQLSLLHAYEDPYETgllldgsshanlragrtqvrrEARAALMPVLAKAGLEQYEVLLRNGNSRRVLeFEDRERSGRDALFVLERERSVVEHLMSGGVCRWLIARGESDVLLV--- +>tr|A0A0Q9EUN3|A0A0Q9EUN3_9GAMM Uncharacterized protein OS=Lysobacter sp. Root96 GN=ASE45_05555 PE=4 SV=1 +AMFKDILVPQLWGDISMAALRVACSIAVPLQGHVTALVGGSVASsiADareyrpagdyrsmcdslevtadEVARGIEDELKFSGV---SWGIRRnsaywLTASEIAIRHAR--YADLLVIEQPQAGLsPRRRFFSE----VLSGAGRPVLLVPDS +>tr|A0A1Q6XW91|A0A1Q6XW91_9BACT Uncharacterized protein OS=Acidobacteria bacterium 13_2_20CM_58_27 GN=AUH13_16020 PE=3 SV=1 +AELGEIIVFIDGHTEAPSILEFAGLLAEEHGAHLIGVFMQPAPKvttaQTfargkgirevmqvqeqeigGIEAHHRALFEDTLRR-HAVQSGSewrslPYLSSDVGVHAY--YADLVMISRPePAGDtaGPPGLAES----LVLSSARPILLIPPH +>tr|L0IFC6|L0IFC6_HALRX Universal stress family protein OS=Halovivax ruber (strain DSM 18193 / JCM 13892 / XH-70) GN=Halru_2976 PE=4 SV=1 +---MTFVVPFDGSDLAEAALVRAVEYGAALDVAVTAVTVVPERTRYarekswigrdenydpgrvveSLRGRVETLAPEASFDfeRIREFPPEAEIAEHIGALALEHDPAVVFLGSDNVGRVVTP-LASVGVHVAAEDDYDVFIVRR- +>tr|W0K441|W0K441_9EURY Universal stress protein OS=Halobacterium sp. DL1 GN=HALDL1_10225 PE=4 SV=1 +---MTLVVPFDGSELAAAALVRAAEFSAVLEEPVLAVSVVPEgGASFarerdlidadeqfemetvvaRLREAVRSLCPDAEFRhlVVDRYARAGTVAKRVRRVAREAEASMVFIGSENAGRMVTT-VSCVGASVAADDAYDVVIVRH- +>tr|A0A1H3ATT7|A0A1H3ATT7_HALVA Universal stress protein family protein OS=Haloarcula vallismortis GN=SAMN05443574_1314 PE=4 SV=1 +---MTLVVPFDGSELAEAALVRATEFSTVFEEDVLAVSVIRKgNVKYarehdwigpneefdletvvtALHKQVMALCPSSDFRhtVLDRYAPAGAVAKAIRKMAKREDASMVFIGSENAGHLVTS-ISSVGGSIASDDAYDVVIVRH- +>tr|F4L4B8|F4L4B8_HALH1 UspA domain-containing protein OS=Haliscomenobacter hydrossis (strain ATCC 27775 / DSM 1100 / LMG 10767 / O) GN=Halhy_3939 PE=4 SV=1 +--MDSILCLTDFHHNSAQPFRYGLHLTRHLHNELYVAHVEDSADFPtvedsvnldeniateqlDALQKLRQFIQTNTPEedqklPVRGVIVGDNLWDGIEVLTGKYDADLIIMGMRNRMGLAGRIFGGLASKMINLAEVPVLMTPPG +>tr|A0A133USI7|A0A133USI7_9EURY Uncharacterized protein OS=candidate divison MSBL1 archaeon SCGC-AAA259J03 GN=AKJ39_03705 PE=4 SV=1 +---ERVLIPYFGENLPKRAETRALEKLEK-GGELFLLHILDEAPTRslryrtgqfgdgsemvktfrktmknvqekkagKYIDEVKSRAGKKGIS-VKPLFTSGSPGEETVKAVEKHSIQLVIVEDL-RDTVTEIFAGDEIDYISNKAPCKVETVSS- +>tr|A0A0Q3HU24|A0A0Q3HU24_9FLAO Uncharacterized protein OS=Chryseobacterium aquaticum GN=AR438_10465 PE=3 SV=1 +YEFKKILFPVRVLDHLNDKLELTLSLAKKNKSIINILGISDQNDVTsltTAYLDVKKKLFIKSADYTSDFLLTEDKAVHISKFSKEENADLIVLNYEDEESWKSFFSENFLKKIINNTEIPLFFLKP- +>tr|A0A0Q4DRS3|A0A0Q4DRS3_9FLAO Uncharacterized protein OS=Chryseobacterium sp. Leaf201 GN=ASE55_13655 PE=3 SV=1 +HTFENILVPVRILDNLTEKLDLSMAIAKKNRGVISLLGICAEHDIPeikSAYLELQKTLAENTRQYHAEFMITRDKAIRISEFSRDDQADLIILNDKDEDSWKSFFSENFFKQMVNNTDVPLFFFRN- +>tr|I2EZ46|I2EZ46_EMTOG UspA domain-containing protein OS=Emticicia oligotrophica (strain DSM 17448 / GPTSA100-15) GN=Emtol_3823 PE=3 SV=1 +SSFQQVLFPIGNTSANVDfdNYWALKNMIPSDDLEIDLLGISRFEDYEtsdRVKEKVSELsnfIKKDGLKASFQNIFCDNITRFILEYASINQSDLIVINPNIDSDWEKFVLGNNMRKIINQAQCPILLIKP- +>tr|A0A1Q3X269|A0A1Q3X269_9BACT Uncharacterized protein OS=Bacteroidetes bacterium 46-16 GN=BGO69_14430 PE=4 SV=1 +LDFRNILFPVRPVLNALSKYKMVFPIIKKNNARVLLMGAINEQESEkvkTIKQMVDSTavqMKSQNIHVDRKLYFGKGIAREIIATSNRKNTDLLVITAALRRGLKQFFVPGFVQKMINESVIPVLCVKP- +>tr|A0A151G8R8|A0A151G8R8_LACPN Nucleotide-binding protein OS=Lactobacillus plantarum GN=AYO51_07960 PE=4 SV=1 +-----ILVAIDNHISAFKITQYAIELANALDKSLYFVHILDDSLPkykrnprnpwersnldalsEFYLKDCANMALDTNVNHVFHSLIYGRTKNTLVRLSNMKNVALTIVGASGYDNLYNNRIGHIAQYVSCWSKGTVIIVR-- +>tr|K7YYK8|K7YYK8_BDEBC Universal stress protein OS=Bdellovibrio bacteriovorus str. Tiberius GN=Bdt_3123 PE=3 SV=1 +MINHSLLIADELEHkdeaslkRSQVNRRFASDLSVRLNCPVSLLYVKTLKDIPGrlalsyaekakvishKHHQLAPVMNNFAV-PGKLIVKFGSPVKEISAAVKDNSVEALIVGSRALKGMDRFFLGSVAEEVVRNVKRPVYILGPG +>tr|A0A1G6C471|A0A1G6C471_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Flavobacteriaceae bacterium MAR_2010_188 GN=SAMN03097699_0454 PE=4 SV=1 +NKIKKILIPISFSEGSANSLRQSFSLF--ENTELILLHCYPPYAYNReydfgqisydkgiegmLVEFYRKHRAKKIAQNIKLIAREGSVSETIAEISG--DYDLVVMSKRKLQETGGYWFSDRVIFIAFYSHCPVLLLP-- +>tr|A0A024IYW4|A0A024IYW4_RHIRD Universal stress family protein OS=Rhizobium radiobacter GN=BN949_03751 PE=3 SV=1 +KTPKDIVVYIDTADVSVCRvyIDYAVSLASAWDAHVVVAFVPEDLIATpshgfargqainsmitsfegrrhdaeeQLRGLLSDVASATGVN-CELRICSGETGEALMLHAR--HAALAIVGTGRDPDR-AETALTVSEDIIFASGRPSILLPTF +>tr|I0ANE9|I0ANE9_IGNAJ Kef-type K+ transport system, membrane component OS=Ignavibacterium album (strain DSM 19864 / JCM 16511 / NBRC 101810 / Mat9-16 +SKINRVLVPVRLRSDFDVtniktiETKLLEKINSKKPLMVTLLTVVSENEKMIAQNFLNNLQSKLETLKVDKRIIVSeKPLESILNNLKT-GYDLLVVGATEKVNTNDSVINPFIDHLIKLAPCYSLIISSS +>tr|A0A1Q4SG75|A0A1Q4SG75_9CYAN Sodium:proton antiporter OS=Scytonema sp. HK-05 GN=NIES2130_06145 PE=4 SV=1 +KRIRRVLMPSQGGPNITLAAQLVSHLAHQNSLEVTVLFAESdkkprrksvstvatAVKETTAEAAVATVAEKIqlptdAPVPVQTKIESGtNKAEVILKEACK-GYDLIVLGATERQRSRGALFNLLVDRVVQEAPCATMVVKSN +>tr|A0A0D6NH87|A0A0D6NH87_9PROT Universal stress protein UspA OS=Acetobacter orientalis 21F-2 GN=Abor_001_083 PE=4 SV=1 +---SSILVVWDNSVCAHKMLQASRTVLARASLLHLLAPHGQELPYSLLPPVMMEEH------RLGQPFSLPRVMHTVATAKLAYPADLVVLGFDldctHNTQSGGGIANSSAGAALQAARVPLLV---- +>tr|A0A1F3KAA9|A0A1F3KAA9_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWF2_43_11 GN=A2X09_13325 PE=4 SV=1 +NHFDKVMLPLNVFRRWRNKLETAIRICRLFKCTLFITetnpGVVHPEEYRNRIEEIARILTEADIDfILVPGQPDGDYDKVILNKAISARIKMIVLMSDEEEGGNHFKPGPWDEKLIfNEEQIPVLCLNP- +>tr|A0A1F3KPS6|A0A1F3KPS6_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWF2_43_11 GN=A2X09_16540 PE=4 SV=1 +NeGYQRIVFPISNDMEVRQMVRLAISLQKRFGATLLLIqdyedEPRFKAQLEIKTQQILEELRRYDVQyRL--sRSEEGDFAANVISFAAVENADLILVMSLADGETPGFFFNTWSEKIMfNTAQVPVLCLNP- +>tr|A0A1V6JFT3|A0A1V6JFT3_9BACT Universal stress protein family protein OS=Bacteroidetes bacterium ADurb.Bin012 GN=BWX51_00447 PE=4 SV=1 +NKFSPMLFPVNLFRGWAKKAKALTHLSQWFGKQVIVVenhsSVMFASEIERERYRFSEKLNSFGLEcTFASYLLQGSYTNQLAYYAKRYKAGLLVLMNDEEEESLHFRPGLSETKIIrSKIGLPVLCVSP- +>tr|A0A1G0VA43|A0A1G0VA43_9BACT Uncharacterized protein (Fragment) OS=Ignavibacteria bacterium RIFOXYB2_FULL_36_7 GN=A2330_07370 PE=4 SV=1 +HSFKKLGLAITSSPTGIALLKEAKRLKDIFNAELFLIHVEEKTPEAEKSLKSIIDNSGLSFQDTQLIWASGDPANTILNTSKNAGVDLLVAGALEKEGFIKYYIGSVARKIMRESSSSLLILK-- +>tr|A0A1X6XNV0|A0A1X6XNV0_9MICO Osmosensitive K+ channel histidine kinase KdpD OS=Brachybacterium faecium GN=FM106_19630 PE=4 SV=1 +---VKLLTYLDEEHiqGTEKCLRWTARLAAAFRSEWTLLVIENEEDEHDehddlmreQRFKVMKLAQSLGAD--IVTLSGHDTLDTLTHYAKMTGITDIIIAKQRNHSHVHRLFKqELEDDLIQrLPQVDLHIIPYH +>tr|A0A0Q8N302|A0A0Q8N302_9CAUL Uncharacterized protein OS=Phenylobacterium sp. Root700 GN=ASE02_11480 PE=4 SV=1 +------MVVVGGEPASMRRVHQVIDLAGRLGAGVTGAFLRPMFPLSdygaggawmsqgllqeaveahalvvdrteARAQRAFLAAAELQHLAADWIVLDTV--QQLVERAR--LSDLVVVPPGPLPEGGEVTI--SAGQLGLACGGPLLVIPDH +>tr|A0A0Q6NJ39|A0A0Q6NJ39_9RHIZ Uncharacterized protein OS=Mesorhizobium sp. Root102 GN=ASD12_05920 PE=4 SV=1 +MGYKDILVFLDGSVGNVARVDFALSLAKAHGARLTGVDVDSAAAFAGEWSERAKSLEEtfhasanrFGV-DVRFKVADRTSQEWKNYYTP--YADLVIATQPHREVAD-MILPEVPGDLLTSAGVPMILLPRD +>tr|A0A239SJ76|A0A239SJ76_9BURK Universal stress protein family OS=Pandoraea sputorum GN=SAMEA4530655_02403 PE=4 SV=1 +MSLRKICVHVDDTATGAARLRFSAELARQHEARLSGIYLPHRpgavhsgqlqssgehFQTEAHSRTALQAAEHlfsklcaeADI-VGDWRTPYGAAPTLLANAAR--ATDLCIVGQPDAPGGVAALGLDGLGDVIRWAGVPVMGVPHN +>tr|A0A239HGP7|A0A239HGP7_9BACT Nucleotide-binding universal stress protein, UspA family OS=Granulicella rosea GN=SAMN05421770_102394 PE=4 SV=1 +--VQEILLFSDFTPESTSAAPYALMLGQEFGLPVDVCQLLPvvvEDNPRLRRQLAEDYCQSmkhvladenAVWCQPAFQLERGMQLEQIVDRAKSHHAGLIVLGAHTESLVGRHLHTSFAYQVLGRATCPVFTIPRL +>tr|W0A6M1|W0A6M1_9SPHN Uncharacterized protein OS=Sphingomonas sanxanigenens DSM 19645 = NX02 GN=NX02_09315 PE=4 SV=1 +-MVKSILLHIHDDCGQAERLAVALDLARAHQSHITCVQVTPFNSYvvgdpfgglyasselldalqardDEERERIEQRLKSEDI-SWDWEHADGNAADALVSCGR--LADVLILSRQNKGQDDTPEPLPIVADVAIHARAPVLVVPPG +>tr|W1KL11|W1KL11_9SPHN Uncharacterized protein OS=Sphingobium chinhatense IP26 GN=M527_02575 PE=3 SV=1 +-AIRDLLAVVDTSDCDEQFVQDALSFAELHQARLTLLVLSviPSPEYgnmygppfivlrdflgavEAKQQRIAGWASRAGI-EIRTVSDlPEGIYTSASVHAR--YADLVLFGPQDA-YGYPLIRRQIIESVLFESGRPVLVLPRE +>tr|A0A1M2ZMU4|A0A1M2ZMU4_9SPHN Uncharacterized protein OS=Sphingomonas sp. 66-10 GN=BGN95_11390 PE=3 SV=1 +--MKNILLLVHDDDGQEARLSAALAVRTALDGHLVCLDVIVTSDGfyrmgggpigmlvleerqkeeRHNKAAVHARLVADNI-PFSWNDSVGELDTILIDAAG--LADLVVLNSYLSDDIADPDMAAKIRAILRRVSTPILAVPRH +>tr|F2IEF2|F2IEF2_FLUTR UspA domain-containing protein OS=Fluviicola taffensis (strain DSM 16823 / NCIMB 13979 / RW262) GN=Fluta_1482 PE=3 SV=1 +HKIKTIVMTVDLSRESVQVVKYASRVAKTFNSKMYLVGQKYSDEGlmqkiEVNLKVANGYLKDHGLEANIHLLENTNFEKNLIGYCKEIKADLLAATCYQ-DGFSLFS-TNLVQSLSENELsIPVMTLDG- +>tr|A0A1V6BKZ1|A0A1V6BKZ1_9BACT Universal stress protein family protein OS=Bacteroidetes bacterium ADurb.Bin141 GN=BWX95_00446 PE=3 SV=1 +RPVKKMIIPVDFTREVKQVLSVVIRYAHLFNAEVILFEQLNRDSFiqhriTNNLNYFTSVLNDEKIVFKIVKKEfSlDDKCEVVTKEAAETNADIIVTTIDPDKGITDYIMGVEEQKLLANELqLPVLCVNI- +>tr|A0A1Z9FZC6|A0A1Z9FZC6_9FLAO Uncharacterized protein OS=Crocinitomicaceae bacterium TMED135 GN=CBC95_03110 PE=3 SV=1 +NGYDNIVVPLDLNFETKQKLELVAKISHYFDSQVHLITKDEDDDFiknklKANQLWAVNYLKEKNVKHSSHLVEkGATLTEGIFKLSKEVDADLIAIMNLQDDTLLGILENSFQEEIVANDLkVPVLSVHP- +>tr|A0A1S2DGL6|A0A1S2DGL6_9GAMM Uncharacterized protein OS=Salinicola sp. MIT1003 GN=BC443_05995 PE=4 SV=1 +-MQNSILIPMGKKSASMAALRKARGIAQHDHTRLYLLHVVEPRETgdvlgaatgaathaldkedvaraEAFLEERWNRLNEPMA-AVNFLIKDGKLSETIAEEARRLKVDTIIMGTSKSSPKWEGMIG----KIRKSTPCKLTIVDEE +>tr|A0A1J5DYA1|A0A1J5DYA1_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium CG2_30_63_29 GN=AUK47_07050 PE=4 SV=1 +---NQILVAFDDSRYSGRALAYAIAVANSGGAKIALAHAIPPLARYfkevlfpyaamgvdeveieaELLDNAKARLGEAALklvgadskVEFETHVTTGaSPATGLVQLVDQLDASIVFCGAFGDTSPILGRIGATAQGIIANAHKPIFVVRD- +>tr|D1Z015|D1Z015_METPS Putative universal stress protein OS=Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 / SANAE) GN=MCP_1965 P +NLYNKILIPITRTSNMKFLVNFVDHFLK-PGGEITFLHIIASDLFAispaewrramSTISTTHLLTATEGMRVDYRVKNSLSVASGILEEADAGDYDLILLATSTYRKRLKHIFGSNLDEIVKKARVETIVFR-- +>tr|D1YW66|D1YW66_METPS Putative universal stress protein OS=Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 / SANAE) GN=MCP_0616 P +ILHDSVVVPISRPETIESIVNIACDMLA-DDGTLRLLYVIEVPyQLPlefaetrktkatELLAMAADHSRKRGFTPRQEVVVARDIPQAILDMADRYKADLILMGSSQRSVPEKVLFGSIVGRVLREAPCEVIVYS-- +>tr|K1KKU6|K1KKU6_9BURK Uncharacterized protein OS=Sutterella wadsworthensis 2_1_59BFAA GN=HMPREF9465_00072 PE=4 SV=1 +---TGFVLV-VERPDVQEVIREASRLARNFSGDWHVLWLGKPGESrehRCRVAETLAFAESLGAV--TAMTSGSFA-AEVSAYVREHNLSMIAIADMG-llaTM-----RRrHLLRHVAP-K-ITFVILSSN +>tr|A0A1R0ISP4|A0A1R0ISP4_SULTH Uncharacterized protein OS=Sulfobacillus thermosulfidooxidans GN=BFX06_14765 PE=3 SV=1 +--MQRVMVAVNGSQASLEAVKAACTLIN-PEGEIIAVDVEDIAQFYqdyalnayggalvlephdydqewekearqvhsRVEAIAQQYQVKLRWEVLRLEPGQGSVAEMINQAALKHHVRAIFVGRHRGAQFMEGLLGSVPRWLVTHSSLPVVVVPP- +>tr|M0CM35|M0CM35_9EURY Uncharacterized protein OS=Halosimplex carlsbadense 2-9-1 GN=C475_13717 PE=4 SV=1 +ETIDSILLPVGTGPHAALAAEAARAVARHADASVTVLHVVSPDAAAEETADGEDLLTFADHVlgpdvRSETELKAAaDTTDEIVRRAK--EYDFVSIGAPEQkSGLKEIVFGSVQQTLSELNGVTVLMSRDS +>tr|L0JMZ6|L0JMZ6_NATP1 Universal stress protein UspA-like protein OS=Natrinema pellirubrum (strain DSM 15624 / CIP 106293 / JCM 10476 / NCIMB 786 / 15 +NQPTDILLAVGTGPHSVLGAETARAVAKASGASVHALHLITSSDDGPARQKGRKALSLAEYVlsdlpNVECETREVeTATDELLTEID--NYDLSLIGTPTKsSLLSRLFAQPTSEKVITQSTTSVITVRQP +>tr|A0A0S7BM31|A0A0S7BM31_9CHLR Universal stress protein family OS=Flexilinea flocculi GN=ATC1_131391 PE=4 SV=1 +--IHRMMIAVADLEADKEYLRSAIQFSKKYGAWVGIVHVVKRQTMlhsewmKKYQAEIEDMLETEGV-QGKFFPLYGNLTKILSERAF--WSDLSLFKLKYRPQLKKiTLTEDGWNAIIMRIPGPICVIPE- +>tr|A0A1V5Q4C4|A0A1V5Q4C4_9CHLR Stress response protein NhaX OS=Chloroflexi bacterium ADurb.Bin344 GN=nhaX PE=3 SV=1 +--IQRMMISVRDPIEDFDYLQSAVCFCKQFNAWAGIVHVVKRPSMldsewiRKYEQDIQTLLEKENV-KGKFFVLKGNLLKNLSDRAF--WSDISLFKMNYRPSPSRyRSLGSGWNSIFMRVPGPIFVTPD- +>tr|A0A150WP32|A0A150WP32_BDEBC Uncharacterized protein OS=Bdellovibrio bacteriovorus GN=AZI86_02415 PE=4 SV=1 +----RVVLAVDTEAPpTKKALRRFARLVRPLGTPVDILHVQRKANFvasligastgpkesEAILASTLEDLRSLNLDgKIHTIEEEDSVAATIAKFANNQGAWITATSSPTRDIRHRLVWGSTTQNLLEELSCPLLVLRSS +>tr|M1P219|M1P219_DESSD Kef-type K+ transport system, membrane component OS=Desulfocapsa sulfexigens (strain DSM 10523 / SB164P1) GN=UWK_00939 PE=4 SV= +---EKILVPVTDMDDLAEVYPVVAALDTVGEHQIQLLYLISSDTDQDDINAHTERVyhwlkEQPKRVHLSVKAVPTDSRvECIQQEAE--KHDIVVMGAIRAQGVRKFFFGSLADSLAKKLKKPFIVVYD- +>tr|A0A1M7Y761|A0A1M7Y761_9DELT Kef-type K+ transport system, membrane component KefB OS=Desulfopila aestuarii DSM 18488 GN=SAMN02745220_02318 PE=4 SV=1 +---ENILVVFTEIDELAAMYEIIAALDSIGEHKLRLMYLVPSDAEEKEIRFLEKEVanwleKQSNGLRATILVSPVDSRlDAIEDAAE--DADVVVMTAGEASGVERILFGSLVDSVAVKVRKTLIVVYN- +>tr|A0A1W9M9W4|A0A1W9M9W4_9DELT Uncharacterized protein OS=Desulfobulbaceae bacterium A2 GN=BWK76_10440 PE=4 SV=1 +---DRVLVPYVHAEELEIVLPLLEALATVVHPRLTFLHLMSSDSSEEELEQARDEQarwlyARFLDARVRQRIEASDCRtESIRRELY--RHDLIVMAGQRQPGLARFLFGSLGLATARSCRCNLLLVIA- +>tr|A0A170PE19|A0A170PE19_9CHLR Pyruvate-flavodoxin oxidoreductase OS=Ardenticatena sp. Cfx-K GN=CFX0092_a0442 PE=3 SV=2 +---GPIIALYDGSATGLRALRLAAELAE-QGGDLRVLLWASDEEEAFERREFAAQLLEESGVEAQIQHLSGDLPLRVLQWVNRQKGNLLLLGGGD-----NHLPPDIFSLLLDEAEQHILVI--- +>tr|K9H3F2|K9H3F2_9PROT Uncharacterized protein OS=Caenispirillum salinarum AK4 GN=C882_3146 PE=4 SV=1 +---APLLVPFDGSDAARRALDAACTLAE-DGPAERVAVLAFGDADALA--AAARDICAAHGTVPRVQALP---PLTLARLVRIadFPEALLVLPAQL-----PMTLGLSTPDLIDRLGCSVLLV--- +>tr|C8X118|C8X118_DESRD UspA domain protein OS=Desulfohalobium retbaense (strain ATCC 49708 / DSM 5692 / JCM 16813 / HR100) GN=Dret_0824 PE=3 SV=1 +---DPVLVIYTGSPLSKQALHMARWLMHDQKRRLKVLVPAEQNATMEPRRQEIHGLMADVTDRIQLQSFPVRSIEAFVHLLQEEGRGPLVLPCDE-----Y-WLGPQLEGLVSRLPNPILLV--- +>tr|B3EN43|B3EN43_CHLPB Uncharacterized protein OS=Chlorobium phaeobacteroides (strain BS1) GN=Cphamn1_2124 PE=4 SV=1 +---GPILVLYDGSRGSKRALETACSIAS-AKNTLHIFLIANTESAASRLREETASIIGDRKKKTELHVLPWTDSAMLAQCIHMTGPGLVVLSDSS-----EAISPESVYRLIDATNYPVLLV--- +>tr|E1YLQ4|E1YLQ4_9DELT Putative uncharacterized protein OS=uncultured Desulfobacterium sp. GN=N47_E45490 PE=4 SV=1 +---KPVAAVYNGTGSGQKTLDTSVYLAQSYDAPLTVILLGDSDADIEHKQRRAEEMLQYSGIRVDFRHLIKPIMAELSVYIRQVEMGPVVLPNME-----DLFEGEELCGLVEEIDNPVLLI--- +>tr|A0A0S8BWL9|A0A0S8BWL9_9DELT Uncharacterized protein OS=Myxococcales bacterium SG8_38 GN=AMJ62_07475 PE=4 SV=1 +---RPVAVLLDQADSGSRALEAGIELAEASSRPLLVFLADPSPRAWNEVRRRLQSF----GPKRaAIHRVREAEREVLAAAIRRASPTVLIVAAGE-----GGFEELRLTSLRQELRCPVVVV--- +>tr|A0A0C1RJ58|A0A0C1RJ58_9BACT Universal stress protein UspA OS=Methylacidiphilum kamchatkense Kam1 GN=A946_09470 PE=4 SV=1 +---PPFGVLINPSKDFLPILTFAANLAKKFNGGLTLFVFNGTLSSAQK--NYVE-ALASDMAQLsVIEG-LGKDPMALASTIAEEKIGLLIFSMSG-----IDLKKATLKDLLRKLNCLVLLS--- +>tr|T1B519|T1B519_9ZZZZ Universal stress protein OS=mine drainage metagenome GN=B1B_06500 PE=4 SV=1 +-MYRQLLIPVKEASEVEPTIDIGARLLE-PNGEIRILHIIPTTRMPQVTREWRASVNivvpahetgAALDVRVEPEVRANvDVPGEILESAEAHEVDAILMTLAGDRRSRNPFVGHTASAVLHHARCDVVIVN-- +>tr|Q1NSH8|Q1NSH8_9DELT UspA OS=delta proteobacterium MLMS-1 GN=MldDRAFT_5054 PE=4 SV=1 +-MLQNFLFPVHPGKSPTQKLLAMAQFAGLFKAEkIYLLLVTSPNNSkqIKWLKELEQELLELGL-PVERLHRHGHIPSQITAAART-TTSIICFFKKWKNPLQKALAGSIVSDVIRMSDEPVLIYK-- +>tr|C8X5G2|C8X5G2_DESRD UspA domain protein OS=Desulfohalobium retbaense (strain ATCC 49708 / DSM 5692 / JCM 16813 / HR100) GN=Dret_2377 PE=3 SV=1 +-MLRNFLFPVYA-KSPVNTVLAQAEFIRSFEPEkVYLLYVASGNSSrpIKRIDRIEKGMRELGL-PVERLVRYGHVPSQVVTTAEA-TQSIICFTKKWKNPIKKAVAGSVISDVVRMSDEPIMIYK-- +>tr|A0A1F8NIQ9|A0A1F8NIQ9_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_13_66_10 GN=A2Z66_05255 PE=4 SV=1 +----RLLICIDPRVPDRATFEYGHRLAQAAAGPATLLGVVSDRARDAEARSVLEPLMNEanrVTPNFQMRVRVGIASSEILLEAQEAHDELIILGVRRARR-GHAAPGSTARAVLEQSEAPVLLVQKP +>tr|H6SLE9|H6SLE9_RHOPH UspA OS=Pararhodospirillum photometricum DSM 122 GN=RSPPHO_02188 PE=3 SV=1 +TLTMKVVVHVDAGESWPRRAEAALRFvSLRGGGRILGVYGqmatvlpayayhGDKAAIGdEAAPQRQKFFEMLsgieGISPDWHTIHSANPDFIASELTAnAQYADLTILGQNDPR-TADRVPADLAEQVVLNCGRPVLLIP-- +>tr|A0A0S8IBX2|A0A0S8IBX2_9CHLR Uncharacterized protein OS=Anaerolineae bacterium SM23_ 63 GN=AMJ88_01975 PE=4 SV=1 +---GYSLIGIGREPRDPNHMRYAEAISRAMGLCPVLFHVSPPDESLEEGERLLANARSMlSSKDVEVLHVEGNVENGIVNELKRRPYQLLVMETSFSDP--DQPASQLSKRLANRAKVSVLLVRNP +>tr|A0A1F8Q2L0|A0A1F8Q2L0_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_54_11 GN=A2136_10760 PE=4 SV=1 +---MRILILVTKMPEDGPLVSFGGLVAKLTQSSLTLLHVAPSKAKQERTDQVLNQAADLlAGLEVERRLCWGKPATMAILEMRQGNYDLIVIGARQASTAMEQSLSLASRAILQRAPCSVLVVRGG +>tr|A0A1M7QDL1|A0A1M7QDL1_9BACT Uncharacterized protein OS=Chitinophaga sp. CF418 GN=SAMN05216311_108110 PE=4 SV=1 +VPIRKSILLYDGQPSSVYAIKMFSYLLPVLNAlPSEVITVKNSDDDLHLPDnRLMKEFMKRHQPDAAYTVLKGDAEEEILLRLRSEdATAVIVAGAYKRGVVSRFFRHSMVDVLMRELRWPLFIAHQ- +>tr|W9RI82|W9RI82_9ROSA Putative urea active transporter 1 OS=Morus notabilis GN=L484_025992 PE=3 SV=1 +LRLHSIILSMPEA------------------ERIYLQQ---------kdkaKKKDIFDHQDNqavpSNSSSRTRSVL-------------------------------------------------------- +>tr|A0A1Y2BAZ9|A0A1Y2BAZ9_9TREE Na+/solute symporter OS=Naematelia encephala GN=BCR39DRAFT_557944 PE=3 SV=1 +LSTYVGFSHQPTYMST--------VPFLmGVDAS---DVVVIWEYALQnllgtgsnhsk------------------------------------------------------------------------------ +>tr|A0A1Y1HVH9|A0A1Y1HVH9_KLEFL Urea transporter OS=Klebsormidium flaccidum GN=KFL_001180190 PE=3 SV=1 +AKIDAILRSNPEY------------------EKAYTHV---------kakeMSPPPKD----------------------------------------------------------------------- +>tr|A0A139DDT4|A0A139DDT4_9ALTE UspA domain-containing protein OS=Marinobacter sp. T13-3 GN=AWU57_4082 PE=4 SV=1 +------LIAIDPEDDheGKRALDAGLDLLDE-DGELHLASVYSPGGGgffphvaeeapeekEAEVHKKLDLLVRKYLPmnrEATIHVVAGNIGEKLVALAGQLSSDLVVLVSRGSNKRWS-LRKATVEYVAVNAPCRVIVLPA- +>tr|W4GLI4|W4GLI4_9STRA Uncharacterized protein OS=Aphanomyces astaci GN=H257_06567 PE=4 SV=1 +-PTTSFCICVDGSRVARVACDVGVSLR--RQGMVHVCCIDEFSTESRyspefITKDITALCRQQGVPDGKFVVRAqaqrltqSTISSQLLELRDSCRADFIVVGAVGTKGPQPSQLGSNTMRAIRGSPVPVIIVPP- +>tr|A0A1V9YYM6|A0A1V9YYM6_9STRA Uncharacterized protein OS=Thraustotheca clavata GN=THRCLA_09149 PE=4 SV=1 +-ATPSFGIFVDGSRNARLACDVALSLR--RSGEVHICFIDEFAANASysldfVVDDFTQYCRQNQVPKSKMSVKSqavrmtQSMTTQLVELSDNLNVNFAVLGTFGGKGPQPTQIGNTAMGVVLQSSTSVILVPP- +>tr|A0A0T5ZN84|A0A0T5ZN84_9BACT Universal stress protein UspA-like protein (Fragment) OS=Candidatus Dadabacteria bacterium CSP1-2 GN=XU11_C0057G0001 PE=4 SV=1 +RRYQTIVIAMALDERDVTTLRHAAYFAQAAGSQtVYMAHVTPTFDLPPEAAvqspdvvlpidediehrlrqiYTEQQIEFPPGTRIECAVRQGSMVPEIVRLAAQKSADLVCLSRRPHEDHDP--LSDSAVKVLRIAPCSSFLIPAS +>tr|A0A150G4J9|A0A150G4J9_GONPE Uncharacterized protein OS=Gonium pectorale GN=GPECTOR_67g295 PE=4 SV=1 +LQYNRVLLTIldanpFLSDGSRTAVATAALMARQYKSKVTVLVVDEPGtenqDPTRRLESITWHLRERGCENFELVEKAITspASVLVGDFADEIAADMVVLSSEAVHAKHVD-----ANQLAEFVSCPVLLLP-- +>tr|A0A0C1XIB5|A0A0C1XIB5_9CYAN Uncharacterized protein OS=Hassallia byssoidea VB512170 GN=PI95_37035 PE=3 SV=1 +RGFQKIAFAFDYWRTLSLPTEPLAWLLQTFQSELTVLQVMEESISaeaEAELRQLQHTFSTAANRNITFHtVHAGRVPEALNNYVLHNEPDLLALCATHDSLLRRMFHRSTIRHLSSVTKCPLYIFPFE +>tr|A0A1F3Q664|A0A1F3Q664_9BACT Uncharacterized protein OS=Bacteroidetes bacterium RIFCSPLOWO2_12_FULL_35_15 GN=A3F72_14365 PE=3 SV=1 +GTISKIVFAWSYETNYPVLISMLNELITIFNPKIiftpliTFLHVSK-HPSplsNETFLLLKKEIGSEikEKIKIEFEeIVSDDIPESINNYMEKSKSDILMMTVMDRGLIGNIFHHSVSRKITGIAEYPFLVMHV- +>tr|A0A076HW10|A0A076HW10_9BACT Uncharacterized protein OS=Hymenobacter sp. APR13 GN=N008_18315 PE=4 SV=1 +----RLVFSADFSTLPLHTLPRLSALAEAFPGTLDLVQFYAPTERSRRlaLKQAQTRALRQLTwPHVHTHLLeDESALEGVSEFCARQQAQLLIVAPASRAELLHYFDACYTTTQAYHTRIPVLVVRSA +>tr|A0A0H4VMH5|A0A0H4VMH5_9BACT Uncharacterized protein OS=Rufibacter sp. DG31D GN=TH63_03855 PE=4 SV=1 +----KIVYSLNFHDIDTSVIQRVQALARPFGASIVLLYLHGKIETVELcqLQKKAARLKEQFPyAEMSAVFQeEEDLLEGLNDFAEGHSPDLFVMATRDTHLVHEYFSGHYRKTRAYHLNTPFLNLYQA +>tr|A0A127B3C3|A0A127B3C3_9BACT Uncharacterized protein OS=Rufibacter sp. DG15C GN=TH61_12065 PE=4 SV=1 +----EIVFSLDVTDTNEAVMKRVQKLAQKFNVHLTLLHLHSQLDGVSFcqVKKAAATLKTELPyPNLDIVCQeEDDLLEGLNSFSGRATPDLFVLATRDTHLLQEYFSSDYRKTSPGHLRTPLLNLYQA +>tr|A0A1G1T7A2|A0A1G1T7A2_9BACT Uncharacterized protein OS=Hymenobacter sp. CCM 8643 GN=BEN47_12300 PE=4 SV=1 +----RLVFSADFDALNLHLLPRLSGLANAFPGPLDLVQFYPRTARPRRrqLKQALGRAAAQLTwPTITEHLVeDEAPLEGVSEYCARTLAQLLIIAPANTAQLLRYFDLCYTQTQAYHTQIPVLVLQAT +>tr|A0A1M6QC97|A0A1M6QC97_9FIRM Nucleotide-binding universal stress protein, UspA family OS=Desulfotomaculum aeronauticum DSM 10349 GN=SAMN02745123_00964 PE=4 SV=1 +----RILVPFNGTDSSWKAINYALDMAKRNNLIRITVIAVDSRDYRfmsvnpnnnpfsiiddfynyliNQTKKIKDLFLKESV-PLNVMIEKGDVAKSILKAVDDLYIDHIIMGRGKLSTL-EVILGSIIYKVIADIKIPVTLLR-- +>tr|A0A1F9FUF8|A0A1F9FUF8_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFCSPHIGHO2_02_FULL_44_16 GN=A3C46_05570 PE=4 SV=1 +--VKTILMPIHLSPSFQKVAERGITFLKAFGEkyHVLLLHAYLVPHVDqkeliqkndevkrqsheglEALKKTLKNIVSNGNMTFETRSHLGTWENVISNVAATEKVALVLLPFGDDD------FMRRISHMLERISCPLLLLPSS +>tr|A0A1I0SZY4|A0A1I0SZY4_9NOCA Nucleotide-binding universal stress protein, UspA family OS=Rhodococcus kroppenstedtii GN=SAMN05444374_103185 PE=3 SV=1 +-SPVNIAVLHAPTPEGDAALTAASQRARETSAPLTVLIVHHESPATEVAAAAVRESVADSVRatvgDTETRYrelgpsNGADAIATLIDHIDDANYDLIVLGTKRRSTVGKLLLGRDIQRIVLEVTAPILLVKP- +>tr|A0A0B6KI38|A0A0B6KI38_FRANO Universal stress family protein OS=Francisella novicida GN=CH70_191 PE=4 SV=1 +---PYVLVCCGYDEATPSLLRKGKLLATTLNARLIAVFVQKPNkvatkLNFGVIRRYKMLASSLGYN--IDHILGDRLSDSILEYAKSIGATDLVIGKSIRPKWKDKLfGSVVYDIIRNNNNgMQVHIVSIN +>tr|A0A1W7A1I5|A0A1W7A1I5_9STAP Sensor protein KdpD OS=Macrococcus caseolyticus GN=kdpD PE=4 SV=1 +---QIIAVGMTSSPTSHEVIRAGARMAKAFKAELVGIVVENEDsIDSVVLNENLKLLDALGGR--YVKLYGDEV-EQIGDWCRLNRVDKLVLGRSLKQKWF--Q-DDIITKINKNYQeINVIIISNA +>tr|A0A1F3T9F3|A0A1F3T9F3_9PROT Uncharacterized protein OS=Bdellovibrionales bacterium RIFOXYA1_FULL_36_14 GN=A2202_08540 PE=4 SV=1 +---FRILVPILPSSDGEYLIRMTRRISSGLNAQWIAAQIDGQRknneNEDRHQKKNALLAKQLGAE--VTSIHDTSFLQGMRRLVKEYQITHLVISKKQKMLLk-------QLSALSKSFPdVDIILLSSD +>tr|A0A1T5AN72|A0A1T5AN72_9SPHI Nucleotide-binding universal stress protein, UspA family OS=Pedobacter luteus GN=SAMN05661099_0888 PE=3 SV=1 +RAIKNVLIPVNFSASATHAIETGIGMCMRHGATLHLLQVNRDSVMphpagrnallmdlrlqarkndQDALEWKAKSIAQDYRISCFFHLREGQFAKTVASVAKDFYCDMILLERQIPSSFAGLINTHSAYQILFQTDCPVMVIPA- +>tr|A0A0E9LZQ8|A0A0E9LZQ8_9BACT UspA protein OS=Geofilum rubicundum JCM 15548 GN=JCM15548_13104 PE=3 SV=1 +SEIHKIVVPLDVNEKDQSGLEKIADFAQALQARVNLLYVDMDGetPPDLAIEKMRDLAKEYHLANYAISVVSSHTLeEGIQGFVRKNNPDMIAVLSQGKGKIKKLIFGSSTQDIIKEADIPVFITK-- +>tr|A0A1Q7QFN8|A0A1Q7QFN8_9ACTN Uncharacterized protein OS=Actinobacteria bacterium 13_1_40CM_2_65_8 GN=AUI42_02840 PE=4 SV=1 +--PRSILASIRGGASSRVVASTAAMLADAYGSELTLVHIQTDSQHpdrsrreWQFFEQIVEELHRPST-KVRLH-RHDNPAGGILLEAV--GHDLVIIGSRLSPSNPNILVGRSLLRMVRQLDCPVVMVRPK +>tr|A0A1M3EFP7|A0A1M3EFP7_9CELL Uncharacterized protein OS=Cellulomonas sp. 73-145 GN=BGO38_03590 PE=4 SV=1 +-----------------ACVDAAAGL---GLTDVRLVHVLDEETEAgweggplglmgrgrrrpddrlgrtcnpldeagsHLLTAAAARLGGRS-GGagspgsgPEVLQLHGRTETVVLDACA--GADLLICARDGVrTERGPHSLSKVTRYVVDHAPCAVLLVWPE +>tr|A0A0D5YPT8|A0A0D5YPT8_9FLAO Universal stress protein OS=Muricauda lutaonensis GN=VC82_569 PE=3 SV=1 +TKMENILFPTDYWSKyKIKELRSLIEIAEEYMAKITVLHVKElpENDLTDKQEQNKKHLKNClkEVPYQFTEIQGKLMPDAILEHIEDHDFQLLAMMNKEHSFFERLLIKQNVDQIGFHVKIPFLIIRD- +>tr|A0A084THB5|A0A084THB5_9FLAO Uncharacterized protein OS=Mangrovimonas yunxiaonensis GN=IA57_11740 PE=3 SV=1 +KGLRDVGFATDFSITdYGDGLALLKDVATAHNAKISLVHVLkKEKELTPEQLTSQDALEAYlnPLHVTLFMLTDVPIEIGTRIFSESRQLDMMCVIAKKHSFFEKVFNKSQSKSISHHAKVPLIIFNE- +>tr|F4B079|F4B079_DOKS4 UspA domain-containing protein OS=Dokdonia sp. (strain 4H-3-7-5) GN=Krodi_2354 PE=3 SV=1 +NEPDSIGFATDFARPySHEDLQPLIELTKLWKATVRMVEVYeK-PEITQVKKDHLQQLEDLlsGVDYRFHTVPeFSSLENCINVFDDe-LNIDLLVMIDYPKTFFERLTREPVVKKMTFHTTLPFLILPS- +>tr|A0A0F9LNJ3|A0A0F9LNJ3_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_1559730 PE=4 SV=1 +EVPGKILFPTDYEIEfAKDCLRFLLKIAQQHSSKIEVLNVSYGNELSEAQQDNKRNLVKVlkDFNHSFHDLPEQNVIQAINNFQLNHKTNLLVMVKNKHTFVERMFFEPLIKKIGLHIRIPFMVIPE- +>tr|A0A150XUP0|A0A150XUP0_9BACT Uncharacterized protein OS=Roseivirga echinicomitans GN=AWN68_14540 PE=3 SV=1 +HKLRSLLFAADFEHIeDIDALGIIKALANMFTAEIQILHIGeGWAELNRMKTKEAAKVVEYfgQTDHSYYFIKeKLDVEDAIDQHLEHHRNELLILIARKHHFPGNLFKKRVTKKTVMRTTLPLLTIPD- +>tr|A0A0F2NT36|A0A0F2NT36_9FLAO Uncharacterized protein OS=Flavobacteriales bacterium BRH_c54 GN=VR77_12375 PE=3 SV=1 +SSPSTISIATDFKEIkKKNIFATLQPLVKDFKPEITLFNVTeEMKSIGTDEKQMAQSIANIldVADIKTSYFKHEDVIYGTKEYVKQHNTSLMVLVNKKRNFFEDLFHISFTKQISFHAEIPLLILHD- +>tr|A0A0A2MR00|A0A0A2MR00_9FLAO Uncharacterized protein OS=Flavobacterium subsaxonicum WB 4.1-42 = DSM 21790 GN=Q766_03090 PE=3 SV=1 +TSIKKMLFLTQYEKFeM-DILQKAKEIADIFGAHIDVLQIKlHHEPIEAII---IDKWKEHfnK-ADINFHVLaTNAIEETALDYIELNHVNMVTMPVHHKKFFKRLFSFSLSTQMAFHSKVPVMSLHA- +>tr|A0A090PYY2|A0A090PYY2_9FLAO UspA protein OS=Nonlabens ulvanivorans GN=JCM19298_278 PE=4 SV=1 +--------------------------------MLHLLYIAQFDKLSQRQIEVKEFWESRfrESETKYTRHDLGDGTTVINNFINKNDIDLLVLVNSKHSFLESFLKTTTIDALGLNLKIPFLILQN- +>tr|A0A1I9XH78|A0A1I9XH78_9FLAO Universal stress protein OS=Maribacter sp. 1_2014MBL_MicDiv GN=YQ22_01440 PE=4 SV=1 +ENIQEIGFPSDLNIAyDIKVLETIKDIILLKRSALRLLYISgTNEALSQNQTKVKNFILDYfkDNVCTYHNITGKSIDESVQCFTESRNLDMVIMVAKNLNFLERILFRPTVEKISYHTKAPFLVIHE- +>tr|A0A1H1LMK6|A0A1H1LMK6_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Gramella sp. MAR_2010_102 GN=SAMN04488552_0890 PE=4 SV=1 +NPLYHIAFASELIYEfNPESLKTIKAIAEKSGARITVIHDGkETEMSQRQWKN-YNSFKSNfeGLEVSLAFSSnHIEVSKSIAEFVKHNKVEMLCMEYYKHSFVSNLFIEPVVEKIDRHLSFPFLILPA- +>tr|A0A1U7DN26|A0A1U7DN26_9FLAO Uncharacterized protein OS=Seonamhaeicola sp. S2-3 GN=BWZ22_01065 PE=3 SV=1 +SSLKKIAFTTNHINIfTIEELETLKWLVAFCKSELYILHVAdEH-HLAQKQMQNMEFFDAYfpNAFHDFIDVNYKDMFDTVHKYLTDNNINLLSMISEKHSFLERLFTRHALETFAFSIDVPFLVMER- +>tr|A0A1T0CK26|A0A1T0CK26_9GAMM Uncharacterized protein OS=Moraxella lincolnii GN=B0682_01600 PE=4 SV=1 +-TPSSALLAFDNKPTCHRLLDWVVEMPLLRGMTLHVVMVAEITNSnQDALREAYVKLTQAGYKCKKQLIHSRHVASALLYYQQEHKLDMLVSGAFGQSRLRQWLQGSDTEHLLQGSDTAYLLFP-- +>tr|A0A173ME75|A0A173ME75_9BACT Universal stress protein OS=Filimonas lacunae GN=FLA_1808 PE=4 SV=1 +LYVRRIGLACDFNNVADItPAPAITALVKDFNAALHILNVGKETELASDIVRESEVLESllGEVKPQYHFIAHNDTNQALMDFVENYHIHLLLVLPRERDFADKLLHKSHTRELVLKSNVPVMALHK- +>tr|A0A1M3FZH3|A0A1M3FZH3_9SPHI Uncharacterized protein OS=Sphingobacteriales bacterium 46-32 GN=BGO54_17670 PE=3 SV=1 +SKLKRIGLGIELNEVIKTiPVDFIKRLQQQFHAALYVFHISIVPgaPLAGERKEEAGWLSEilKEMDPEYHYLYQENVEEGLCRYAEKYQLDMLIVFPHRRNFFKQLFFPGHTRALALHSNIPVLFFHD- +>tr|A0A1M5CDA6|A0A1M5CDA6_9BACT Nucleotide-binding universal stress protein, UspA family OS=Flavisolibacter ginsengisoli DSM 18119 GN=SAMN02745131_02885 PE=3 S +APISNIALAYDGSGL-NGTEQKIREFVQALHARLHVIHVQVSGke---------SPGIKDllPELTPQHQTIRNEDFVSGIEKYIHSHHIDLLIVLPHKHNIIERLFYRTHTSEVLQKVTIPIMAFPE- +>tr|A0A1F2X8H9|A0A1F2X8H9_9ACTN Uncharacterized protein OS=Actinobacteria bacterium RBG_16_68_21 GN=A2Z12_07430 PE=4 SV=1 +---MRIVIATAGVLSPEPVARFAERLAGD-GGKVYVTTVIEVPRSFldeirseqwhpltegspgwsmeedaviaryveergeRITEPLLAALIARGLDAEVVFLEGEDPAGTIIAAADRIDADLLIMGATK-HLFDEAAWESVSTRVVREAGRPVLVVPT- +>tr|U0EKD9|U0EKD9_9VIBR Uncharacterized protein OS=Vibrio coralliilyticus OCN008 GN=N779_21135 PE=3 SV=1 +-PRRPVMILMDGSPSDTLAVDYAHQFLQPQNHRLLLVTVNVVEGVEgegvretpvqemGQLKHYLQKLSERGFDvmsEAISDVLPMQVAKTIIRRGEALDAQLLVMVKHSHaSFIQRALSFSVTQEVTEQARCPVLVIP-- +>tr|E3PY31|E3PY31_CLOSD UspA OS=Clostridium sticklandii (strain ATCC 12662 / DSM 519 / JCM 1433 / NCIB 10654) GN=CLOST_1226 PE=4 SV=1 +MIKQKIMVCVTEQKTCERLIKKGIELTKDNDTEIFVLHVATKDIKViedpraaEELEYIFEESKKYGAS--VTVLKSNDILKTLSKFAIENDIDYMILGETRLQNEKDSVIFKLRKELGAT-KTQIEVVP-- +>tr|A0A1C6FH22|A0A1C6FH22_9FIRM Uncharacterized protein OS=uncultured Ruminococcus sp. GN=SAMEA3545435_01169 PE=4 SV=1 +NTKSAVLACVTSQYNCDRIIRIAKEIADSSDCELRVMSVLKPMSDYssvsDEIEYLYLIAKESGAD--MTVMFSDDAPKVTAEFVGDNNVERIVTGMHDGKD--NSFLVKFNELSPT---TPITMVS-- +>tr|M0N024|M0N024_HALMO Uncharacterized protein OS=Halococcus morrhuae DSM 1307 GN=C448_00857 PE=4 SV=1 +--MTLVVVPVryPLSEHSRRTLKTAIDVADEHDAALSVLHIDLYHSSKRVTQSALKNAVEEafgPLSNTRYAVRPGFLVeETILDEIALEDADIVVIGRKQTSRWRRMV---------------------- +>tr|A0A191TM91|A0A191TM91_9BACT Uncharacterized protein OS=Arachidicoccus sp. BS20 GN=A9P82_11360 PE=4 SV=1 +--MKTIIVPVDFSDESKEAAFYAAEMAKQSSQSVMLVHIMPryiqseSGRREEFLSETKRKLNQLRLrtemrgkdkIHVCTRIYSGSFFHEINKLIKSLDFFAIVVSGKYKNKTGTA-LRTKIIDTARNCNIPLIIIPQS +>tr|H7FW26|H7FW26_9FLAO Putative universal stress protein UspA OS=Flavobacterium frigoris PS1 GN=HJ01_03373 PE=3 SV=1 +RPIKNIGFTTRYRNKDKKALSSVLEIAKKLNAKVKCLYVKSS-TSDVTCETINLWEKVYGSEPISFEIVNSdDIKETVLAFVSANNIDVLTMLTYKRGFFDGLFVPSYGDKSQYDIDIPILAIHSD +>tr|F0NXI6|F0NXI6_WEEVC UspA domain-containing protein OS=Weeksella virosa (strain ATCC 43766 / DSM 16922 / JCM 21250 / NBRC 16016 / NCTC 11634 / CL345 +KPEKRLGFASRLLEKERRTLEKLIVLAKRNGGPLELVHIAKDNiLDSDAALVKNFWEREFKDDELEITVLVNkDINKGIADFVTQKNIDVLCLIHRDMNSIERIFKGNYSKKLLQSLQIPILVYPEI +>tr|A0A1H5Z6L4|A0A1H5Z6L4_9SPHI Nucleotide-binding universal stress protein, UspA family OS=Sphingobacterium lactis GN=SAMN05421877_106249 PE=3 SV=1 +QGINRAVFTTLFREKDKSALREMLIMSNAIDAKIDCVHVLHNRNVADVLLQTEAWQQEFKDENIEYILLDEveSVENTIANYILENNIDIMGVVKRNRSFFDRLFNSSISNNLAFHSKVPILVFHEE +>tr|A0A1M5HHV0|A0A1M5HHV0_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Flavobacterium fluvii GN=SAMN05443549_102240 PE=3 SV=1 +KNIKTIGYVNHYTAKDKETLGVVLDMAKMINATVKSLYVRTH-KSEIDAGTKKKWEENFSEEPIAFFEVRNeEIKQMTLDFISHQEIDVLTMLTYKNNIFEGMFVPTYAKKNVSEFEIPILVIHA- +>tr|A0A1H6S0B0|A0A1H6S0B0_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Myroides marinus GN=SAMN04488018_102245 PE=3 SV=1 +KQLENIIFTSRFELEEESTLDDIIKGAEANNAHVKVVHVKSK-GCTSCEEVYNKWKEKYKDSPVSFHLFNAeNIEKTLLDFIEHEKVDTVATIKRNKSFIENILSKSITQHLAKHLKVPFFVYKSK +>tr|A0A159ZVD0|A0A159ZVD0_PSEFL Universal stress protein OS=Pseudomonas fluorescens GN=TK06_07655 PE=4 SV=1 +SQYQRLLLILNPAQRHSPALHHAAALAAASGAHLHVTALIPSLDILslleegpreearqnylqdhrHWLEDEADKMRRRGLRITTEVEWAQKMGKQILQHVTQIQPDLLIKQVQHEPMLKRAFFTPLDWQLLRNCPVPMYLVGAT +>tr|A0A1W9F2R2|A0A1W9F2R2_9GAMM Universal stress protein UspA OS=Serratia nematodiphila DZ0503SBS1 GN=AK51_23625 PE=4 SV=1 +MAYRHIVVATDLSEDAEFLLGKGARLAAALNAKLSLIYIdihragyyvdlgvgdynYTDRTFSERVKNMLNAIKGQSSYPVEEVIVsRGALTEELNRVAKEKGFDLVIFGHHHDVWSR---LVSSARQAINELNVDLLVVP-- +>tr|F4C431|F4C431_SPHS2 UspA domain-containing protein OS=Sphingobacterium sp. (strain 21) GN=Sph21_3250 PE=4 SV=1 +-QPKRILGTIDFSKYSNRVYTLGEAFSKG-IPDGRFscihvakapVHFFLGLNQSEINRLLQEETEAkkskwlrqyQIEGKIETVRADGkHIASAILAHAQNYKMDMIIMGVKGSSSLTNLFVGGVTNEIFHH----------- +>tr|A0A0P0NG16|A0A0P0NG16_9SPHI Uncharacterized protein OS=Pedobacter sp. PACM 27299 GN=AQ505_11090 PE=4 SV=1 +-KPTKVIEAIDFSKYTAKVMQWGSLIKKYNqIPELTFqpinisklsWKFFPGLSTAEIKKNTQEDLKLksekwaklyPTATPLKVIPAEDkNIASALMYHVKKERADVLIMGVQGVTSVTTLFMGSVANEVLYL----------- +>tr|A0A1W9L9T6|A0A1W9L9T6_9GAMM Uncharacterized protein OS=Beggiatoa sp. IS2 GN=BWK79_03510 PE=3 SV=1 +KHFKNILICTHPEFTDVEIVDRAAKIAKGSGAAVKVMHVIADYPEdmnswwnvrnpkelhekilrerQNFVEGIVERVKAAGVTNIESALRwskEGQEFLVVVREVLKHEHDLVVITSRRKNRLAKLVLECPSLDLFRHCPCALWVTQS- +>tr|B9LQ45|B9LQ45_HALLT Amino acid permease-associated region OS=Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34) GN=Hlac_1 +-ALDVVNIGAGGGPHHMDLLSLIDRMGER-DAEIHVINITPEGGEG-RPENTEATVSGLPNAsSVQIHnTTAQTIADGLVDRAR--ENGgILIIGATRTRRLRRRVFGSTPDNVIKLAqgsGVPVLVYSSP +>tr|A0A1J5N292|A0A1J5N292_9DELT Universal stress protein family protein OS=Desulfovibrio dechloracetivorans GN=BerOc1_00854 PE=4 SV=1 +--MKNVLIVVDKSESSLWLAYYAMGLTRRMAVNVSILLVVDEEidgragdneewigSPEKRLESILAEGRSEGT-RLDYYVVRGRMEEEIPKFIRENSVTKLFIGAPpSGRRSLYLKLMRVIDAVNTTTRCEVEVVQK- +>tr|A0A1X7DEE7|A0A1X7DEE7_9DELT Uncharacterized protein OS=Desulfovibrio sp. K3S GN=SAMN06295933_1788 PE=4 SV=1 +--MNNVLIAVDTSESSFWLAYYAIALTKRIPMDVSILMIEDENhkiksgkgdewigLPEKRLESLLAEGHSDKS-HINFYSTKGNFEDEVIQFILENKITTLFIGQPePRRAKLDTQFMALLERIGSRTDCHIEVVQK- +>tr|A0A1V5H4Q2|A0A1V5H4Q2_9DELT Universal stress protein family protein OS=Deltaproteobacteria bacterium ADurb.BinA179 GN=BWZ01_01869 PE=4 SV=1 +KKPRRLLCYIDFSDHSYYIVEYAFELAKLVDAELFVLHSvtdikkaagfYVPHINTDLLEDQVAKAARdkmyaichqvvgEEIDADHRLVTQGNPVEDINRVIEEKGIELLILSHEMSRGSLSGFRSDHVERFMKNATIPFLVLP-- +>tr|E4T1V1|E4T1V1_PALPW Uncharacterized protein OS=Paludibacter propionicigenes (strain DSM 17365 / JCM 13257 / WB4) GN=Palpr_0536 PE=4 SV=1 +-DLKRVLLPIGFLEEELEKAQFAAAFGRFCNSEIKMLLANDYGSKAAANAEKMKSLFDKFDFKYSLDKATKDsfkVEQESVQLAENMNAGIIIVSASRDYGLDDIIFGPKEYHVVNKSTIPVLLVNP- +>tr|A0A0R3TY69|A0A0R3TY69_HYMNN Uncharacterized protein OS=Hymenolepis nana PE=4 SV=1 +---RSILFPVLDNSVGERLFNWYCQYFRRPEDQLTVLSIVEPTLQMQkagvssddplveaamvvgrnIVRRFLQRAHERSIPCRGVVQLDISPALSIVRTARERGTQIILMCPRGNvaGESEKVEFDSVTEYVLRHCPdIALAIVPPT +>tr|K6YAG5|K6YAG5_9ALTE Uncharacterized protein OS=Aliiglaciecola lipolytica E3 GN=GLIP_1016 PE=4 SV=1 +---LEVLACVDISDDdfdnhvlNRKILAVSDKLSQSINAQMHVIDCYDGEIGTmhidynnkrgfkreatiqqKHIEKLELYIKEYALSNDVLHSVEGLPDEAVPDKAASLNAEVAVIGNNEDKHFMDKMFGDTAMALAEAMPCDILVLKP- +>tr|A0A0K1IRS4|A0A0K1IRS4_9EURY Amino acid transporter OS=Haloferax gibbonsii GN=ABY42_05205 PE=4 SV=1 +----HALVAISHdiSKARERAlIQVASRLARANDGRVTVARFETVPDQtslayasavespadVEFERQTDELDDEFGVPIRCGTIVTHDTRHAVVNYADNQDVDFLLVEHPTGtKRVSERLFGTDTSWILRHAPCEAGLLKGP +>tr|T0SN40|T0SN40_9DELT Amino acid permease OS=Bacteriovorax sp. Seq25_V GN=M900_1362 PE=4 SV=1 +----QIVITLLGKERSPEMlVEMGVALS-ENDDLIEVAHLTEAPEQsdlsdfieeppelKSLRRRVIAMAIEKGKPLTFDPVVTHDISKTIFELSQRMHSKWLFMEWSG-KSRGTITLHSPITWLKAHLECHLVIFKDK +>tr|A0A1H4KZJ3|A0A1H4KZJ3_9BACT Nucleotide-binding universal stress protein, UspA family OS=Terriglobus roseus GN=SAMN05443244_1417 PE=3 SV=1 +MGNDQLMFATDLTERSLEPIPLLAALMTPST-HLTVVHVTESVLEtdaRAAMDTVRARMALYLPDqamkhQVKWKVIHSsEVTKALIEAATEDKAELLIMGMHRSGELNAHLPLKTGFQIIIGAPCAVLSV--- +>tr|A0A1M6JJJ8|A0A1M6JJJ8_9BACT Nucleotide-binding universal stress protein, UspA family OS=Reichenbachiella agariperforans GN=SAMN04488028_101218 PE=3 SV=1 +---GELLVLIGIRDYRTESIARIREFAEVMRMNVHIAHVTEPHDLlhKSISDRLEDFARAHGFTDYKVHVIeSGQKVEQVQAFVEAWHIDVVASISEGDSGIARLIYGSDTEDFINHVDKPVLAVTM- +>tr|A0A1P8XFQ9|A0A1P8XFQ9_9MYCO Uncharacterized protein OS=Mycobacterium sp. MS1601 GN=BVC93_25095 PE=4 SV=1 +-----MVVGVDGSAGSMAAVRWAAGEAAGLRLPLRLVYAIDPDDAttalptgtarlrssaQSTLEQAENEAQRvAPQLDVECLMVNGRPAVTLAGLG---RPAMICVGASAPAVPHPGHHANVVTELILAADCPVVVFQDE +>tr|A0A0L0DCK5|A0A0L0DCK5_THETB Uncharacterized protein OS=Thecamonas trahens ATCC 50062 GN=AMSG_06119 PE=4 SV=1 +---NKFLVCVNGSKHSKWAMRYTMEIMQE-NDRLYLFHAYSPKENPKYKDEALALVEElvteakyanEWLSIASILLPTKKVKEAICDMALALDMSFVVLGTTRRARIVSKFAGNTGLHVVHHSPLPVIVVTDS +>tr|H1Y839|H1Y839_9SPHI Uncharacterized protein OS=Mucilaginibacter paludis DSM 18603 GN=Mucpa_7017 PE=4 SV=1 +--MKKISVVFDGLKFANNTLTYGIKLGENSNALLSGVflesflynsYTLADlvgtqglsqvkmkhllekdeKMRVKSVEAFEQACKKAEI-NYSVHHHPSFAIPEVLRESI--YSDLLLISADETfSHVADQQPTQFIRELLAGIQCPVLILP-- +>tr|V4BJ62|V4BJ62_LOTGI Uncharacterized protein OS=Lottia gigantea GN=LOTGIDRAFT_165224 PE=4 SV=1 +-MKQKILIASDGERDSEWAFDWYCNNLHRPGNNVIIVSCTEIGVklatiapeaiingdetaievfieeenkiLAEKVSKYQKKLRSAMLVGKVLTSCHTSPSEVILNTAASEEVNMIIIGSKG-CGLNRQGVGSVCNYLVSHSTIPVIVCRH- +>tr|L9XA51|L9XA51_9EURY Sodium/hydrogen exchanger OS=Natronococcus jeotgali DSM 18795 GN=C492_12265 PE=4 SV=1 +ETPQRILVPVSSESrHAESLLDLAFAIRDPrVREPVHAVSVVRPESlartrsrvaaAEDRLADLEEYAAGAEV-PIEGHARIDhNVASGLVRSALENRISTLVIGWDGARSREQQVFGHTIDQVLRRTTQLTLVGR-- +>tr|Q8KDB0|Q8KDB0_CHLTE Na+/H+ antiporter, putative OS=Chlorobium tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) GN=CT1144 PE=4 SV=1 +DADEQILLPIAENKPSERVLELAVMIREKrSLNPLTILTVVPNDHeaelnvkkAKKELAPTVDFAASFDT-SLNIVATIDyNICSGISRAVKESQSNLIIFDWPSRQGFLGRMINDATESIVECTCKTTMICH-- +>tr|A0A170YDP3|A0A170YDP3_9PORP Kef-type K+ transport system OS=Paludibacter jiangxiensis GN=PJIAN_1306 PE=4 SV=1 +KRRERIMFTVANPHTLDHLVEFSIAIKNPrSKEDLYALRVVNDNDeahkeqGDRLLLQAAKVASVADQ-WVERISRYDvNVASGILYSAKEYAITDVVIGLHQKLKSRDTLFGLMTEMLLKGVSCSLFIYK-- +>tr|Q3ARA8|Q3ARA8_CHLCH Transporter, CPA2 family OS=Chlorobium chlorochromatii (strain CaD3) GN=Cag_1205 PE=4 SV=1 +APTNRFLLHINHMGTVKELVNVSGMMVTGkMPYSLYGAYIATTREmevnheyrAEKMLERAVISAGAADR-HVTPLLRYDtSIANGLAGVICEQKISDLFVCVEPSSDFPDTLSINKPDNILGRCGVTTFIYR-- +>tr|L1MQ19|L1MQ19_9BACT Transporter, CPA2 family OS=Prevotella sp. oral taxon 473 str. F0040 GN=HMPREF9999_00407 PE=4 SV=1 +EEKDSLVVALANPRMVIPMTNMALMLRSAsATSQLTAVSVVLSD-dteeratAQQGLDYAAKMAATVGV-RMQTHCRRSvNAVTGIVHTAGEHEATDILIGLHQKKSISATFFGKFATDLFDAASQQIMVYR-- +>tr|R4Z0V6|R4Z0V6_9ACTN Putative Na+/H+ antiporter CPA2 family OS=Candidatus Microthrix parvicella RN1 GN=BN381_410038 PE=4 SV=1 +APAEKVLVPVGDPKRSMDVLRLAGMLAAPDTGTVVPVSVLDLEAtqadvkarRAE-LAEAERTILGEGA-EATSVVRLDlTPSAGMLHASVEQAATAVLVGWKGFANRNGSAFGQRVDALLAASPVPVVVAR-- +>tr|A0A1F3JNN3|A0A1F3JNN3_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWF2_40_13 GN=A2W88_16320 PE=4 SV=1 +IKEDRILVPVSNPNNLKYLIDFSIILKKSsKEIPIYPLTVISDPKkaqsmmdsFHKKVETYMVDAASTEH-VLHPVVKRDiSVVSGILSAASQNHITRIIIGWNGKITTSNYFLGTLLENLVRKANQMIVVIK-- +>tr|A0A1G3PF26|A0A1G3PF26_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWF1_31_7 GN=A2015_09390 PE=4 SV=1 +DNTGTFLISIANPVTAERLLDTTILLSNKnSV--INALSIVNDDYntsqniisSKKFHDLLQEKNITANR-VINSVIRVDiNVAGGIIRASKELQTRTLVVGQNRKEKVSDLLFGSMMSKLIDQHPYRIIMCN-- +>tr|D7BNJ2|D7BNJ2_ARCHD Uncharacterized protein OS=Arcanobacterium haemolyticum (strain ATCC 9345 / DSM 20595 / NBRC 15585 / NCTC 8452 / 11018) GN=Arch +---MSVVVPIVQGNRCSQIINRGIAFAESHDVPVVVLlstslDTTTQDDIDDEIDHLTDLLDEKDVAfRIVTRLDNADLATKIRETAIESEASIIIISLAPKPHHGSYQLGHQVQKLLVDAPCEVLVMRDT +>tr|M0NDS8|M0NDS8_9EURY Cationic amino acid transporter OS=Halococcus thailandensis JCM 13552 GN=C451_03784 PE=4 SV=1 +---ARVLVPIHEwlpLADAERLLETAAAIAREQDAEMLVASLAVFARQtpldavqdnedaalaaRESAQEYVETAREFDISASGVAVLTHDETHSILELIEERECDGVILAVDPTTtQRRRLLSGDTVESVVARAECEVFV---- +>tr|A0A173MGW9|A0A173MGW9_9BACT Uncharacterized protein OS=Filimonas lacunae GN=FLA_2882 PE=4 SV=1 +--MKKIIAAFDGFDYSTSTARYAIQLCKECNAHLVGVFLDDVTYhsyklsEItgnggirtekwdmleagdkekreEAASNFEHACQQAKI-EYSIHHNKYVAIHELLHESI--YADLLIVNKTeSFSAYDEKTPTFFMHELLSNVQCPVLVTPLT +>tr|G8TNF4|G8TNF4_NIAKG Uncharacterized protein OS=Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10) GN=Niako_3571 PE=4 SV=1 +--MKKILLVLDAAHIDTEIIHFACNFASLSHSTLTGLFYGNYEEEQpevkmefgapyieeppvysmgpnitlqqleEHMTQFKSTCAVRGV-RCDVHFDNTSYGsESIITESR--FADFLIIKASaTRERKLKDTPTPFVKDVLAAAECPVLVAPAS +>tr|A0A1A9HZZ0|A0A1A9HZZ0_9BACT Uncharacterized protein OS=Niabella sp. BS26 GN=A8C56_07425 PE=4 SV=1 +--MKNILFITNAVSMNWKVLDFACFIAGAAHSSLKGIFVEVATVSKtyilesddeppcgdilggsdimgfetrqgrkdTNIQRFKEYCEKKNI-PCSTLCVEGEPMKAVLVESR--FADLIIAGAAtSAEENRNQFPAEFMKRLLQKAECPLIIAPDH +>tr|A1S3H4|A1S3H4_SHEAM Uncharacterized protein OS=Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) GN=Sama_0722 PE=3 SV=1 +GHFSRVLVATDDGLHAKPALRKAVHLANQSHADLTMLRVQLPKQAGlsqwlqqlltAPNiSHQRQKHPSYPDKDIRLVLKhchAPTLANAVLDELSQRDYDLLILEHHEYSALRCEFGHTEDWQLLQQVPIPVLFVSNE +>tr|B1KGK6|B1KGK6_SHEWM UspA domain protein OS=Shewanella woodyi (strain ATCC 51908 / MS32) GN=Swoo_1041 PE=4 SV=1 +SSYQHILGVFSPYLSSQHALIKALILADKSKSKLTLIQLTTPKFNFmkstnnstdmQPLAENEDLIFQYQNLGLEIEIKevkSNSVSTEVLAEVEQAQYDLVIVNYKHHHPIFHEFFFAEEWSLLRQKQISVMLVGDK +>tr|B8CJZ1|B8CJZ1_SHEPW UspA (Universal stress protein) OS=Shewanella piezotolerans (strain WP3 / JCM 13877) GN=swp_0886 PE=4 SV=1 +ISYHHTLALVDNNSVAQFALNKALQLACKTKAKVTALKVEKPYNNFlnrlglipdnalDPMLFVNKLLSKYQRLGVEVEVKqikNTKDHIAILNETNASDYDLVMINNQHHNTIVSEFLPSCEEHLLRESNLPILIVGNK +>tr|A0A1F3KIP4|A0A1F3KIP4_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWF2_35_48 GN=A2X01_14975 PE=4 SV=1 +CNMKNILIPTDLTDCTKNTISYAIALGVKSNTKLFFYHTETSQERSNkeyaikfIKDIFNEQHLNFEKSQVEFIIEnVAFSNAQIKSTIEKFNIDLVIMGASH-EGLKTTFFGSHVSKLINDVSCPVLSIPHD +>tr|A0A1U1C454|A0A1U1C454_9MYCO Universal stress protein OS=Mycobacterium abscessus subsp. abscessus GN=SAMEA2275847_02068 PE=4 SV=1 +LRIREVTCAMGTRPGARVLLDTALRICKRAETPLRLVSLVSIDPIpggdddqsarERATIHAQQSLETAKLVlppdfPVTSTVAEGPTVEAAVNKLDWHEGDIIMVGSSRLAQPRRLFLGSTAAKMLRVLQVPMVVIPKE +>tr|F8UI20|F8UI20_9ZZZZ UspA domain-containing protein OS=uncultured microorganism GN=LDC_03295 PE=4 SV=1 +-MLQRVLVVFENEKVSEKALVYARELALRMDCEVTLLMLVEMPFQNgshlapkreaireiekrmgKVLAERSAEFLKKGI-VVSAALRIGAPAQELMKFlAERHPFQVVIWGGADDFTERgSVPKNHWMNKMAAKLEGSLIIVSH- +>tr|A0A1W9PS81|A0A1W9PS81_9DELT Uncharacterized protein OS=Desulfococcus sp. 4484_241 GN=B5M56_09520 PE=4 SV=1 +-SPKWVLLVLEDGMVPEESLCHTIGLARRLGCSVSVLMLMEENVYGtpagyeqgcKDLEQALDRIRSEGL-DVRHSLEHGEKASGLLKHiALIPSLSALVWGGKEDIASTrkKRKGDHWFERVRPAVPCPIVSPRV- +>tr|A0A1P8WKS5|A0A1P8WKS5_9PLAN Universal stress protein E OS=Fuerstia marisgermanicae GN=uspE PE=4 SV=1 +HSVKKITVGVEMPEtrpwnaaniaaPSRLAVRQAFGVAEAMGVAVTLVSVLPEISYgffgsdeavesqaetdrteaAAVLEDLKQQYSEKSSRplEVTTTVAFGRPWFQILKAAGTARDNLILCGTRHKGAVSRLLFGSTGLKLLRNAVGPVWLVNP- +>tr|H5SES2|H5SES2_9CHLR UspA domain protein OS=uncultured Chloroflexi bacterium GN=HGMM_F17E05C18 PE=4 SV=1 +---LKLSVYTNGHSATWPALQYGAHLAEALGQPLQLIAIDESDQpllpeaahpLEAFLEQARKLFQEHHV-MYELEIHRGHAEDIIPARVNASAEGLHLVAPLGRPPLRRLFWGRSFRHIMARAVAPLLYVP-- +>tr|A0A0P6Y2Y7|A0A0P6Y2Y7_9CHLR Uncharacterized protein OS=Bellilinea caldifistulae GN=AC812_00130 PE=4 SV=1 +---PPLLIALQSSHPSFPALEYGENLAKVLRTPVRLLCMRQAGSsalLEEQVQRSALALKELDV-LVDIRWADGDLVKAVLREVNQMPEAMLVISDKYRPIWRRWVRFGRFRRLQASLTSPILRVR-- +>tr|A0A1J4ZKY6|A0A1J4ZKY6_9CHLR Uncharacterized protein OS=Anaerolineae bacterium CG2_30_57_67 GN=AUK01_00785 PE=4 SV=1 +---PKLCVFTNGFEGNWPSIEYAAWMAEAMQAKITLTGTQEKDAenfsVEAIFSRAVSLFQQKNI-DYALNLGDDSIENLMARTAQSDSDALFVFSPLGRSRLRRMAQGRSFRQIMVQVDAPLLYVP-- +>tr|T2G8H3|T2G8H3_DESGI Putative UspA domain-containing protein OS=Desulfovibrio gigas DSM 1382 = ATCC 19364 GN=DGI_1013 PE=4 SV=1 +-MNRHFLVTVSDDPQAMHAIRFLGHFFHrKDGLECTLFYVAPRDHDsptamikpdarelakgTAALEAARDKLHHMGWPaehlHIKTMTQRQSRAMEIVDEASRGRYDAVVLGRRGITSFEAFMGSSISHEILEERIsFPLWLCRM- +>tr|G2HBX5|G2HBX5_9DELT Uncharacterized protein OS=Desulfovibrio sp. A2 GN=DA2_3282 PE=4 SV=1 +-MERHLLLTMGGDGGESWNLRFVAGFFRnKSSLRLTLFYVVPDAYSsglgevilsdaqmrqgMEQLARARKWAVEHGFAsenvETRAVPRQFGVVRDIVEEAHRGMYDAVVSGRRYLGWLEQTYTTSVSRGLLGEEIaFPLWVCHQ- +>tr|A0A1Q9S2U0|A0A1Q9S2U0_9PSEU Uncharacterized protein OS=Pseudonocardia sp. CNS-004 GN=BJF90_24850 PE=4 SV=1 +AGTGRVVAAVRDLPNDVAVLTEAALAAMALDATVVPVHCVPLSFGErsvgltdalarghEVLDAAVAQLAADaPDIPVAPRLLRVHPHELVGEGL---DADVLVLGGPRQRIPAR--VGLVGCSAVQHAPCPVLLAARP +>tr|A0A1F9ASE0|A0A1F9ASE0_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RBG_13_52_11b GN=A2162_06210 PE=4 SV=1 +-KIRKILIPFGTSIHTRLATEIAPALGAHFGAKLSVVVVFDPDTPvygrDKRLSEVRQVMEQSSVWADLKVVTEKDVLKGVLKEAA--DADLVLMGGRTGDFLELLLSKSLSEEITEQVKCPVLWVRE- +>tr|A0A1W9PS31|A0A1W9PS31_9CHLR Uncharacterized protein (Fragment) OS=Anaerolinea sp. 4484_236 GN=B5M51_08395 PE=4 SV=1 +RTIEKVVILLDGSVYAAQAIPTAKRICRSMGASLTLLSSVKAYSHgpqeqfeaelssrEGYLAALVQQMRSNDY-TVDYAIRRGSIAEVTHAFVEANDIDLVITTTRGKSGQKHWMKGGVSSKLMSKLSIPVLLVQGE +>tr|A0A1A7V2K6|A0A1A7V2K6_9VIBR Universal stress protein OS=Vibrio mediterranei GN=VME0621_04734 PE=3 SV=1 +MKYKNILLAIDFEHSDAELIKNATDLAFSLGATISLVYVHPNVEYNpyslaywgdiyrefvaeleqkHDTKELEFIVSAYPISKENIYIKNGDVSREMHAVIEIVDADLIILGKHHS---VVNMEGTLERSMRSVAGLDVLLV--- +>tr|A0A0G3ED81|A0A0G3ED81_9BACT Universal stress protein family protein OS=Verrucomicrobia bacterium L21-Fru-AB GN=L21SP4_00017 PE=4 SV=1 +-MSAPVMLALSTFRQSDKAVSRAVDRAATENRPLVIVYVVDVNLARyfigtdlgmypelqqryeddvlrehgriaaERMEHIIREAQDHGV-EVRSAIHTGRFAKECLRIAAEERPSVIITTRSNRPQWVKHFFGSPVDELEESADGPVEEY--- +>tr|A0A162HG07|A0A162HG07_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium GWC2_55_46 GN=A2V21_202245 PE=4 SV=1 +--MKKVLLVLSGHAKAQEAVTFAVKKAKDCNGALIALYLLETGAAsdvfdtftdigfigdkpsaqvseaimkeyrqrgYEELGKVQIKAMEEGV-AFEPLLERGEPVEKVLSIIEKMEITTAVLVKRKRRAFFKYFSRSFADDIAEKASCEVVVF--- +>tr|A0A1G1IJ80|A0A1G1IJ80_9BACT Uncharacterized protein OS=Omnitrophica bacterium GWA2_50_21 GN=A2036_00800 PE=3 SV=1 +-PFRRVLLASAGGRLSDRALGIAVRLGISGSCKVEVLTVSPaSSPALRMVHDKAKYFFDKYNVKATYKIEQGHMKKTILRSCESKETSLLVLGANETDHWKDHRFRSFSEDVVDAAICPVLVVK-- +>tr|A0A172TWW6|A0A172TWW6_9BACT Uncharacterized protein OS=Flavisolibacter sp. LCS9 GN=SY85_14040 PE=4 SV=1 +--MNKVLLILDGLQVPGYLMDAAANIGKMAN--CHIHAIFLNKAPIdpeynyffpndlilvdnplrgeniaaenseiisATIQTFKDVSDLAGL-SYTIDERNDYSLDELLELTA--FSDLLLADAKSNfY-------EYLLSDLLTDSHCPVLLTKQT +>tr|H8KQC9|H8KQC9_SOLCM Uncharacterized protein OS=Solitalea canadensis (strain ATCC 29591 / DSM 3403 / NBRC 15130 / NCIMB 12057 / USAM 9D) GN=Solca_14 +--MKKIVLIFDGSNFSEAAFDFACHMNSMNP--VLLTGVFLSNRDYatafqygfggglvftdwglgeddeqrakISIKRFEALCLNNGI-DFRIHNGLgAYALSEINKESR--FADLVIISSDLFyKNVGGEQPNEYMRSVLRDTECPIILVPEeK +>tr|A0A1Y2K4C2|A0A1Y2K4C2_9PROT Putative UspA domain-containing protein OS=Magnetofaba australis IT-1 GN=MAIT1_03663 PE=4 SV=1 +--MKSIIALTDLTDSCKPVIALSEELAKGMGWRLYVMHVVPPHDAKggpayvgnevddgqprrdaaaalkelrHKLHAQRDELIARGV-DCHAVMVEGQLEEKLLKEVDAINPEFVIIGRHCHDMLYKVIFGNRSDKLLDKLKQPLMVVP-- +>tr|I4ANH4|I4ANH4_FLELS Universal stress protein UspA-like protein OS=Flexibacter litoralis (strain ATCC 23117 / DSM 6794 / NBRC 15988 / NCIMB 1366 / S +--MKTLLVPTNFSLSSAKSLQYSTLLAKEFGSKIIVHHTYPQNSPVHWLSDLENQLHAfvseydfehytgsEDYLKIETSIQQGREKENIINIIKKHDADILILSAKDRTQWEGIPFEMLISQTLEQTLSSVLIVPSE +>tr|F4QTG9|F4QTG9_9CAUL Universal stress family protein OS=Asticcacaulis biprosthecum C19 GN=ABI_44660 PE=4 SV=1 +VSPKLRLHLFGGHAHELNALSLALAMARHDGAHLRILHIAETPFLPeisglgaygagaeanlhepdhvQLAQDAAAYVRAyclhekvpllrpgdspvAGQASAEFRNVSGTPATVVMQQAL--SCDLVVSDWNHQPD----EDLSTTRSVLFGARRPIMLLPR- +>tr|V4R5S4|V4R5S4_9CAUL Uncharacterized protein OS=Asticcacaulis benevestitus DSM 16100 = ATCC BAA-896 GN=ABENE_17820 PE=3 SV=1 +MSIKSILCVYSGNADEANALITAFNLTHTVKGSLRVLHLAEPPILYaatigagyasgqypdgaavkileqsarELTETALKSVTNlsqahsvelvedsvkavAGLAQASFRTLVGTTAECLPKDGR--SVDIIVVGYDNSPD----GNLETVLTALFKTGSPVLAIPR- +>tr|A0A075AYS1|A0A075AYS1_9FUNG Uncharacterized protein OS=Rozella allomycis CSF55 GN=O9G_004665 PE=4 SV=1 +---RSLIMAIDNDESSLKALQWCIKNNFIHSYDnLLLVHSIESGEtkinqeslvdfkacaggdvqsFFKSFNSVCEQLKVNGiFDNAKLLISNNSIGEVLVESCRKFGAELLIVGSKPAGSFIRALAPNVNDYVVRHATCSVLIVKTH +>tr|F6DVC5|F6DVC5_DESRL UspA domain-containing protein OS=Desulfotomaculum ruminis (strain ATCC 23193 / DSM 2154 / NCIB 8452 / DL) GN=Desru_2024 PE=4 S +-MYNNILIAIQGEEG-PQFLQKALELIHPAQGTITILHIKETGLTHygyvdqlassiskeqfidyihelaenqqkKIQEQIIEQGDRWNL-NFAWRVREGSPAQELRKEVAALNYDLLILGTKPKAPGNT--SSKVKEAMLKVFDGSILIIK-- +>tr|A0A0D3L9X6|A0A0D3L9X6_9BACT Universal stress protein family protein OS=Flammeovirgaceae bacterium 311 GN=D770_02370 PE=4 SV=1 +-SIDAMMVCLHLSDIDNKLVAFTQSICQRLQVKkVYFVHNVKTAELSEDFRetfgdvdlskeveaSIADIVAEHftGGCEHEILVSEEPNTEMMMTDlVKRYGVKLTLLGKRMSEKS----TGALGTRLLHILPCSILVFPET +>tr|A0A1N7CN11|A0A1N7CN11_9EURY Nucleotide-binding universal stress protein, UspA family OS=Natronorubrum thiooxidans GN=SAMN05421752_101464 PE=4 SV=1 +RMCMNVLVGLVGSDESIKTLRRTIDRTEEVGDDLTVAIVDKPEakrSQAEMTQQAETLLTDAAV-DAEVITLEGDPGSSLVDYAEQGEYDQLVIGGGTLSPMGKIQLGPITEFVLLNAPTTVKLVR-- +>tr|M7N2R3|M7N2R3_9BACT Universal stress protein family protein OS=Cesiribacter andamanensis AMV16 GN=ADICEAN_03292 PE=3 SV=1 +RRPRKLVFATDLKPFdNPKPVENLLGIARWLQTDIVLLHVHESREGLSPKKEKELQQLQGYfqQQPSVVLQQADDKEEAILQLARQEQPDWLMAVSHHYGLLEGLFHSSLTKKLARETDIPLLV---- +>tr|L8JLT6|L8JLT6_9BACT UspA OS=Fulvivirga imtechensis AK7 GN=C900_00446 PE=4 SV=1 +NQAKGILVPVDFTEAARHAVMNAIELAKQLNTDVYLVNFIPPVkkkrvrkagadieaisidlsssinllrENEQRLADMLKEMDKADV-TVHSEIKIDKLASGVKKQLKNKHIDLIVIGITEAHTVGDSFYKASKARDLIEVTCPIMVCNNH +>tr|A0A1Y0H995|A0A1Y0H995_9BACT Uncharacterized protein OS=Armatimonadetes bacterium Uphvl-Ar2 GN=CCB81_08315 PE=4 SV=1 +------VFASDLSPYSQKAWQQFGRMQAHGLSKVIAVTVVDTRPVDfgpllpdptpfmpnlpvldrdALLQRLKEACPAPAGMNVEHVIVDGTPAESLEPYMQSVGADLLVLGAQGHTWADRVAIGSVALHMTMWGSSTLLLVRP- +>tr|A0A059LNL4|A0A059LNL4_9CHLO Uncharacterized protein OS=Helicosporidium sp. ATCC 50920 GN=H632_c551p2 PE=4 SV=1 +PPPRRIAIAYSSFAVGRALMAFARERLLTPRDAVYVVHSFPRESQPgalagnvmaqtrklvramtlsrtlspdapadrgrhAVTEDNSMDFGAAELAGYDVQLGVvlrGDPRHALAAFCEAEAVDLLLVGARRGSRLRKSLSGgSVSAALADSGACPVLVVP-- +>tr|A0A0S8AR74|A0A0S8AR74_9BACT Uncharacterized protein OS=Nitrospira bacterium SG8_35_4 GN=AMK71_06125 PE=4 SV=1 +---RTIMLALTGDSEDEKAFRFAINACQRVRADLEILYSGQKKDR--VPEWIRSELRSEGIA-YSFIKVDGCVREAVQKHTAkRSDILFVVVESSDRLHMECKKSQKMISKSWKDLQCPLVVVSEL +>tr|A0A1G1GZP4|A0A1G1GZP4_9BACT Uncharacterized protein OS=Nitrospirae bacterium GWC2_57_9 GN=A2078_04815 PE=4 SV=1 +---RRVLLALKQGRIDAKTVKYAVNSAKRIGADLDILFVSSSEGQADpLLEELESGLTAEGVT-YRLIRKQGCLKEAVIDYTNrEKEILFAVVESPESLDADCRKKDSMLSELWQKLKCPLVVVMDQ +>tr|A0A1F9MMV7|A0A1F9MMV7_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFOXYD12_FULL_53_23 GN=A2520_11300 PE=4 SV=1 +---KRVLLGTDKPELATRTISYALHLCQRLGGSLEIFHMLRLPENETehlmrqekePLAALNIALQQKGVV-YQPINGPGCLADEMLRHASvRRDILCVVFDALEPDSAICRKAKENMIAKFQALHCPVVMYAGS +>tr|K0PQM1|K0PQM1_9RHIZ Uncharacterized protein OS=Rhizobium mesoamericanum STM3625 GN=BN77_3294 PE=4 SV=1 +---DHVLIGWKPHEHSRRTMVAARRWLVAAN-RITVLCVDDM-PSRHYETTAREICRHLGVEaeIVVTSSAGRSVGNTILDFGTSVNASCILIGAFKHGYLLELLLGRVTYRLLSHANVPLLM---- +>tr|A0A099K829|A0A099K829_COLPS UspA domain-containing protein OS=Colwellia psychrerythraea GN=GAB14E_0779 PE=4 SV=1 +KFIKSILVVMDDNSDRQTALIQAINIAEKTSATIELFLVVYKNEFvshwnfnqeqldalqkeyiaskLRWLETYLPEVKALDIV-VHFDVVwHADVSCAVLTKAAKVNASMVVKSTQKSSMINKMFFTPCDWQLLEHCPVPLLLTKN- +>tr|B3PLH3|B3PLH3_CELJU Universal stress protein family OS=Cellvibrio japonicus (strain Ueda107) GN=CJA_2593 PE=3 SV=1 +SKPEKIFVVVDPNDTTHIALERVIITSTLRDVkpKVHAFVAVDPNAVDTrtvnenvfrdlswFESAIKNPLINAGI-DFNLEVSwSSEWQKSIMESAKRFDADLIYLPVHATTASSRFLFTESKWELLKGAYCPVVLIRPG +>tr|A0A0F2NXK8|A0A0F2NXK8_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium BRH_c0 GN=VR73_09865 PE=4 SV=1 +ALEEKLLIVVNPAASKQPALDRAVNIAqA-giYEFspEIHLLVTVDQSSTDAradndavyrdgqwLNA-VTQQLQSGGI-EPHIRISwSKDWADSILYSAGVLGVSSIVVSHPGK--SANRAFSDEFWYLVRNAPIPVSVVQSA +>tr|A0A0E0QZH8|A0A0E0QZH8_ORYRU Uncharacterized protein OS=Oryza rufipogon PE=4 SV=1 +----------DGEANARLSQRWGWSAVYGAASMMEAVRAAQAENARNLLVRARLVCERRGVA-AATVAVEGEPREALCRAAEDAGAGLLVVGSRGLGALKRYAHAVTHTPHAHAHTTS------- +>tr|A0A077ZYH0|A0A077ZYH0_STYLE Universal stress protein OS=Stylonychia lemnae GN=Contig6737.g7209 PE=4 SV=1 +------MVAVDGSEASHNAYEVVTqSLFHFPEDILTIAHVFNRSKSYlpfnmhaDTIRQTYDSLIIGYGARAKLLWEENDPQyttkEHVLNLAKSNNVDLLVVGMHGRKGPKAdpTVLGSAVQHLSLNTFCPVLMLKD- +>tr|A0A1L6L4G6|A0A1L6L4G6_9DELT Universal stress protein OS=Minicystis rosea GN=A7982_01999 PE=4 SV=1 +SSSRAIVAATDFSCATFPTLTRAFELGARLHAPVTFVHSVDTIMALvasstfgvaavmlggmlrdavaKRGEILQNVAERLGGGVDTIVLARENAAGAILEVARQRDADLIVVGSHRPDALGWLASGGTVEAVATTARRCVLTVP-- +>tr|I7M3S2|I7M3S2_TETTS Universal stress family protein OS=Tetrahymena thermophila (strain SB210) GN=TTHERM_00459310 PE=4 SV=1 +----NFLVCIDGSNKSYKALNYALNLAQNPNDKITICYAPTPDKQkftRTIDAKLQEDLEQAKHINWKFVELTPsyNATEQIIKHVNscgnEDQFQFVIIGNNGYRAQieDKSFFGRTAEEITIHSNSNIIIIT-- +>tr|I7LX58|I7LX58_TETTS Universal stress family protein OS=Tetrahymena thermophila (strain SB210) GN=TTHERM_00657540 PE=4 SV=2 +----TFLVGIDGSKKSLKCLHIAASLANNPNDKLIACFAPSPDRIkqiDEINQKVQNEMAQINFQNWQYVSLQPnyDSGEAIINYVNlneEVDVQFVIVKYNLYLCIkvIELFLTDRQQRFQSRKRKESILWQ-- +>tr|I0IAW0|I0IAW0_PHYMF UspA family protein OS=Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01) GN=PSMK_02390 PE=4 SV=1 +-----MLVSVSSPWASEKLVGPIADLAARLNAEVLVAHVATLQDDDDAESDATERgeqtlglltkgLREAGVECDGVMLLSDDTPKAILNTARAKGCTCIVLGLTGKGVLKRLIAGDVPANLIRQTDLPVLLLPAN +>tr|A0A059LE41|A0A059LE41_9CHLO Uncharacterized protein OS=Helicosporidium sp. ATCC 50920 GN=H632_c3150p0 PE=4 SV=1 +-------------------IWSIKNLRPEPKGGLYVLHVLpdmfaspaagpayfgdaaDPLVEDALLREAWANLEDvfvskgrqMGVEVTPVLIKESEtkhVGSALVKKAEELEACPLVLAKHTKPNWQQVLLGSTSKFCALNCHRPVLLLHP- +>tr|A0A061SK27|A0A061SK27_9CHLO Universal stress protein OS=Tetraselmis sp. GSL018 GN=TSPGSL018_570 PE=4 SV=1 +-MGKTVMICVeDHFKSSRPAFEWSLNHIVEEDDELHVVTVLPSMAYSavtpavplatagavtavtnqweaqrrvseehaaETLKEASQVVESHNLKlkGFHTHALPACggacgAGSTLVEYANSRHIDVAVLGSRGHGAFKRSLmsvvgLGSVSDHCVHDLHCPVLVVRQG +>tr|A0A221T141|A0A221T141_9DEIO Uncharacterized protein OS=Deinococcus ficus GN=DFI_15750 PE=4 SV=1 +-MIQRILLPLKDLTGDPWPLHWTRQAF--PHVDLCLLHVLVPERREltpfpmmaygsalsttrtaaSSVMRAIEVREALRWLGHGEVILADQAAPAIVQYAETGAFDAIVLGRgpSSRGALERVLGGSVTARVARTAPVPVLLVPEG +>tr|A0A1Y1WL25|A0A1Y1WL25_9FUNG Uncharacterized protein (Fragment) OS=Linderina pennispora GN=DL89DRAFT_202430 PE=4 SV=1 +-----VAIAIKDSPQTIDIIEWAIRQALVPGrDKVVLINVRPAVNGLigdlvssnsdkevaerekshELLKKYASIIKAEGYPIKGVSIRSVDIRGELVRKLMELKCDVLIMGRNASKSMKGRFIGCKVNYLIENSPCPVTV---- +>tr|A0A150GUF6|A0A150GUF6_GONPE Uncharacterized protein OS=Gonium pectorale GN=GPECTOR_7g945 PE=4 SV=1 +----HIAVGVDGSQMSNLAMNTALGLFNsRRGDKFTVIHVSDssktylskhlqPSHLKNFYTDMAHGARVTAEWLCREKEEGRSTCECLTRLADRHAVDLLVLGSWGRKGEKIDMLGSVSSFSLRQAHASIAIVRST +>tr|D8UBU5|D8UBU5_VOLCA Putative uncharacterized protein OS=Volvox carteri f. nagariensis GN=VOLCADRAFT_107074 PE=4 SV=1 +----SIACAVDGSQMSDRAMAVGLSLFNnRRGDKFTVIHISDatktylskhllPPHLKNYYIDMAHGARVTAEWLCREKEEGRSTCECLTRLADKRGVELLIMGSWGRKGEKLDVLGTVSDFSLRQSHCSICIVRST +>tr|A0A1Q3QKI2|A0A1Q3QKI2_9BACT Uncharacterized protein OS=Acidobacteriales bacterium 59-55 GN=BGO25_01670 PE=4 SV=1 +FSFDSIIFATDLAPDAARKAALAVALAQDSLGKIYLCHFMQHPGRTSpdasaqrlKFEAALEKLVpalSYDWCYSNCIVEYGEAASRILDTAKRVKAELIVLGAKKGPRLLTRFEDGIVSNVLALAECPVMTI--- +>tr|A8M6X6|A8M6X6_SALAI UspA domain protein OS=Salinispora arenicola (strain CNS-205) GN=Sare_4576 PE=3 SV=1 +-QLRHVRGFVTAGIRSPTGAGsILVAAAREARWRAGTLIAVHARPLgnvdAQLLHAATARLNDQGHewlaaqlaatgVHAVPEVVVGAPENALLQHSA--HAALLVLGAHQSSGLWTGQPGTTITHCIRQAPCPVMVVPN- +>tr|A0A0S8AI22|A0A0S8AI22_9DELT Uncharacterized protein OS=Desulfobacterales bacterium SG8_35 GN=AMJ60_06580 PE=4 SV=1 +---KKVLVVLEDEDLNLRLLNYAHDLCKRLGGQLEILHKQGPGREDISRSEILQEItkSKDDIV-CTSLAPSESLDDKLIEYGRkRRDILCVVLRIDLMGNKPvkKMKENASSPDWImQKLNCPVMVYS-- +>tr|A0A023NS95|A0A023NS95_9GAMM Uncharacterized protein OS=Dyella jiangningensis GN=CH75_08325 PE=4 SV=1 +-MFKDISVLMMGIASDEALLAAAAQLSRHFQARLSPIQVVDLPELpyntwailpdpgitkahdairqqaAELAERAGRQLAGMQLdaAPFQRMEAlYTDPWTVAAKECF--CTDLIIA-GRSGTGPPAQRETQGIATLILQSGRPILLLPGE +>tr|A0A0Q8DA66|A0A0Q8DA66_9GAMM Uncharacterized protein OS=Lysobacter sp. Root604 GN=ASD69_05405 PE=4 SV=1 +-MYKDLMIPMTGAGADEDALALAIALAKSHGAHLTVLEMVDLPMPlthpwglmpdatmyeahailrergAKNLARLQARLAVESVsSEARLIEAlYSEASRSAARHAY--DADLTIVAGAVGDNADSVVPHAYFVDLLLESGRPVLVVPPR +>tr|A0A1Q3SL13|A0A1Q3SL13_9CHLR Uncharacterized protein OS=Chloroflexi bacterium 54-19 GN=BGO39_01720 PE=4 SV=1 +-MIRTIVVPVDRTEEAKPILNIAAWLSLLLGARVRLLGISNETPlsvkeihpphgditllegsdvyrerlnnqlpyplylqekaetpveevtfsseeeqdMENYLSHLQEELTGSylhyvlPPGRVSSCIEKGPVAQALKDLGREEPIDLVVLPSHRENVLHQLLFSSQPNRVVRQDQLPVLVVPQN +>tr|A0A085TT37|A0A085TT37_9RHOB Universal stress protein OS=Thioclava atlantica GN=DW2_15500 PE=4 SV=1 +MIPKTISTAFLSSSETRWLAPAAARLCRHFDAHLVGVHGLGPLLPMggdlvsdpvilpemlewqsqeaEAIRETFEAALKAEDIAGEFRSPADDgdaREDFLIDGCR--SADVILSAHIP-RQGGRANDIRLQEQLIRQAGRPVVVMDEA +>tr|B1KGK6|B1KGK6_SHEWM UspA domain protein OS=Shewanella woodyi (strain ATCC 51908 / MS32) GN=Swoo_1041 PE=4 SV=1 +----------------KKLLDDSEEIASLLDNNIHLINCFHNNNLSmevsisnstvnhrdtkaQHWLDLIDSAQDYDLEDEQLHLIEGLPDHIIPTIAEQYHVNMVIVGASEHQGWLSQLKGHTSEQIIDQLHCDILAIKPT +>tr|A0A0M2PX44|A0A0M2PX44_PROHO Sodium:proton antiporter OS=Prochlorothrix hollandica PCC 9006 GN=PROH_00765 PE=3 SV=1 +QQIQRILVPVkDLLPRTLRTVRFAQWLGETNGGTVVLLHICVAWTPPEQITAFETSLNQWveqqsgtLNPgrsggetlepnpgatvqvtTLTGESiTGEEVASIILNQAQ--QFDLVVLRSVRRRTAGGFAVSTVTNQVMDNFGGSIVLF--- +>tr|Q3AX75|Q3AX75_SYNS9 Possible Na+/H+ antiporter, CPA2 family OS=Synechococcus sp. (strain CC9902) GN=Syncc9902_1401 PE=3 SV=1 +QPLGRILVPIkDLSASAReqfeLALRVINSSPNLHRTRITLLHVHDPRSDHQDRTWMEEQLIRWrpaaipAER-FHTVLvRGPGIDGAIHRLSR--EHDLVILRTQRRRVaGLPIPGSDRTSKLIKQLPCASMVI--- +>tr|K9TE37|K9TE37_9CYAN Kef-type K+ transport system, membrane component OS=Oscillatoria acuminata PCC 6304 GN=Oscil6304_0661 PE=4 SV=1 +VNIHRLLVPVkNLSPQTLRTVRFAQLFADANSGEITLLHVCARRTPVEQIHRFETDLARLvkrdnssIK--ISITSiPDDDVVKVIMKAAQ--SVDMVILRSIRRRTAGGLTVSNVTTQVIEELKCSLILF--- +>tr|K9WKA7|K9WKA7_9CYAN Kef-type K+ transport system, membrane component OS=Microcoleus sp. PCC 7113 GN=Mic7113_4564 PE=4 SV=1 +KNTGRVLFAAaDQQTSL-vafqQTVTLAKNIA--TELKATLELVMLVTSPGSSPFNP--ESVGLSSD-TPVSLIRGNFVRKVSQMLQ--MDDLLILTAHTQPNsLLGLPGQLVQPeAIARIHPDTSMIV--- +>tr|A0A0W0ZCF7|A0A0W0ZCF7_9GAMM Na(+)/H(+) antiporter OS=Legionella steelei GN=Lste_3088 PE=4 SV=1 +KGINRVITVIgAHAIGV-kfneQYLDVVVDIS--KALGLPLTIMTTNYYHNKLNSKF--EKI-KDLD-FQFIKINGDIIEAVSEMAK--ENDLIIIPSMNLQK-RFDTNKNHIPyALLQQ-TESSLII--- +>tr|A0A1F8KUD7|A0A1F8KUD7_9CHLR Uncharacterized protein OS=Chloroflexi bacterium GWB2_54_36 GN=A2X24_05865 PE=4 SV=1 +NSVQRVVVVIpSNTILP-vtigRTMELVSTLS--KAVNVPTLMLVDRSYQEKMTGLA--KTIEVNQP-IEIRQIEGNLLQFILHQVD--EADLIVVPSSGSRK-IFQSKLGDLPeRLTQTVAGN-VMV--- +>tr|A0A1C4DAB2|A0A1C4DAB2_9BACT Transporter, CPA2 family OS=Chitinophaga costaii GN=GA0116948_105164 PE=4 SV=1 +NITQRLVLVLpHNACYE-agfqHYLQKAVMLS--KQAGARMVVCCTPETRVRIEAWLRATRTSVSLT-YRAFGEAEDLL-ELAGELS--DDDLLMMVTARKGTLSYSKYLDNLPaRLSRSFKNNNIIL--- +>tr|A0A1D9PBJ6|A0A1D9PBJ6_9FLAO Sodium:proton antiporter OS=Flavobacterium sp. PK15 GN=BIW12_11120 PE=4 SV=1 +VLHKRILVVVpPLAEHE-ngfdLWVVKIAKLA--QELSIPLFLECNPATQKAVEKFSVEMKLNIKMT-INIFEDWEDFL-VLSRKIN--EDDLFVLISARKGSASYMNLLEKLPfKLGKHFPDNNKFV--- +>tr|A0A1F2X9Z6|A0A1F2X9Z6_9ACTN Uncharacterized protein OS=Actinobacteria bacterium RBG_16_68_21 GN=A2Z12_07940 PE=4 SV=1 +RRI---VVAAgNGETSAAlplrDAVELGVR------LRSGG--VPLVILSDDLAVSR--AVLGVHHH-KHLREVTGDRIDAVCSVAT--DGDLVILPGPHSDRdGA---------ALAQRLPAVSLVV--- +>tr|A0A1Z4JMC2|A0A1Z4JMC2_LEPBY Sodium/hydrogen exchanger OS=Leptolyngbya boryana NIES-2135 GN=NIES2135_47710 PE=4 SV=1 +SQFQKILIPIeNLTLRSISALQFALNIATATNGQMTLMHVCGRTTSASKIAWIRSQLDLLveklapqVEQiATEIVIiPEDDIGRAIVAASK--SFDLLILRSSQTPNtAGGLILGNLVSQISVQIQCSMILF--- +>tr|A0A136L0F9|A0A136L0F9_9CHLR Putative glycosyltransferase OS=Chloroflexi bacterium OLB14 GN=UZ14_CFX002000801 PE=3 SV=1 +SKPQNILVPARGGPHADLAMRVGLGLNRSGVSLLHIRKAGDP--INVAFKGLERVVQQMPEVEKQFE-VTNEAANLIIEKSK--QADLIVLGTTAQPMSSSASLGYVADQVLREANATVIAVKRA +>tr|G8QZW2|G8QZW2_OWEHD Universal stress protein UspA-like protein OS=Owenweeksia hongkongensis (strain DSM 17368 / CIP 108786 / JCM 12287 / NRRL B-23963 / UST20020801) GN=Oweho_0540 PE=4 SV=1 +--MKVISALIDFTETSKKAVQYAAWIAKHEGAKVNLVHIEASKS--DNQEEIENRLIDFSGiedqnVPYTVSLGDGNYLKKIPTLLQRNQADFVVIGTHGVKGIFQTLFGANVLILVQSLGISALVVQDH +>tr|I3YRQ8|I3YRQ8_AEQSU Universal stress protein UspA-like protein OS=Aequorivita sublithincola (strain DSM 14238 / LMG 21431 / ACAM 643 / 9-3) GN=Aeqs +-IPLKMAFATDYNEFYQlSKLKPITRLVRQYNSQLHIIHVGLEANLDEKQQQNFEKFKNDLTEydtAFHFVPKNGNISKSLHAFIDEREIDLFTLIYHKHAFIKQLFREPVVSRVGKHAHVPTLVIP-- +>tr|Q26DI6|Q26DI6_FLABB Uncharacterized protein OS=Flavobacteria bacterium (strain BBFL7) GN=BBFL7_00758 PE=4 SV=1 +-SPKSIAYATDFKKDDQlQNVTFLKMIIKEHNSKLQLVHFHKQSDIQNDVESQFSHLKSHLNDvefVTHWISSEDSIESNLKQFCETQHIDLVTLMYHKYSFLKGLVKTSTVEKLSFHTDLPLLIFP-- +>tr|A0A0F9IMW3|A0A0F9IMW3_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_1559740 PE=4 SV=1 +-PISQIVYITSFLHNLKkDRLKTLKSIASNYKASLCILHIDNGTVMNTIQERNKEFLSTYLEAtklSFKTVPCDSSKVKTLVQFAKRHKVDLLVMYYHPHLFFDELFREPVLLDLSLYTEIPLLILP-- +>tr|R2PQU8|R2PQU8_9ENTE Uncharacterized protein OS=Enterococcus asini ATCC 700915 GN=UAS_01831 PE=4 SV=1 +---MNILVTLDSLHDSGAYLEKSFKLIQKLqGKQVLLLDVVDTAELEtieavaatfdeelvaskkvALADLVKELQGRYPALAITGSIKTGNPKSCIVKAAKDSQADLVISGSHHYSNVEYlLYHGSVSAYLAKHLPCDLFIIKNP +>tr|A0A0D2VG88|A0A0D2VG88_GOSRA Uncharacterized protein OS=Gossypium raimondii GN=B456_011G001800 PE=4 SV=1 +AGNGLVAVAIDKDKGSQNALRWAVEHLLSRGQAVVLIHVTKPTYETsslaptkytmdrqtkELFLSFHCFCTRKDIQCLDIILEDTDVVKALTEYVSHAAIEKLVLGAASRSGFMRKFRADIPSCVTKAAPdfCTVYTI--- +>tr|R0I8I6|R0I8I6_9BRAS Uncharacterized protein OS=Capsella rubella GN=CARUB_v10016139mg PE=4 SV=1 +VAVKGLIGDKL-GgAGSRRAVRWAVDNLLPKad--RFVLVHVIPTITSIptptgerlpveeveervvemyvrdvkkgfeKVFVPFLKMCKSTSV-tksttILRKHFSDSYPNQVLTVWLWDHSLQTYSPGKNYiARCLDRr-TRGPgVPLTVLKYVPgtCEVYIV--- +>tr|M0TMW9|M0TMW9_MUSAM Uncharacterized protein OS=Musa acuminata subsp. malaccensis PE=4 SV=1 +RPPASTAVAIDKDKNSQQAVKWAIDHLLLGSYAVILIHVKTKPPLNrrypspfgcscvrtyettsdaireqaenemsQLFLPFRGFCARKGVHMTEVVLEDNDVSKAIIDYINTNYIQNIVVGASSRNALTKKFRNPdVPTNIGKLAPefCAVYVI--- +>tr|A0A178U8X4|A0A178U8X4_ARATH Uncharacterized protein OS=Arabidopsis thaliana GN=AXX17_At5g61050 PE=4 SV=1 +DGALIVAVAIKGNnSKTKGVVRWALQEFASQeHVVFKLLHVQPRDSN-svsttrkdlttsvykkdvdrktrEMLLPSRDMFVHREV-qLDIMVLESDDIADAISKAVQDHGISELVIGASSsIIF-SWk-LKRSnLSSRIADATPrfCSVHVI--- +>tr|A2XBG2|A2XBG2_ORYSI Putative uncharacterized protein OS=Oryza sativa subsp. indica GN=OsI_09613 PE=4 SV=1 +APPLTVGLALT-DsKSSTYALQWALSRFKFTkdddAPIFLLIHVLTKLLTVptpmgnhipidkvrtdvadayfkdvhhqaqQMLLLYKNMCHQNKV-kAQVLLIKGNDVSQTVSTVVSDYQIKILIVGVTAr----TRk-PFGNrTSSKICKNVPsfCTAYLV--- +>tr|A0A1J7I7M9|A0A1J7I7M9_LUPAN Uncharacterized protein OS=Lupinus angustifolius GN=TanjilG_32960 PE=4 SV=1 +GVNGLVAVAIDKEKGSQNALKWTIDHLLNRSSTVFLIHVKLKPGSLstspslfgqrsgmqigdegpvgktdpdalnkNIFLPYRVFCTRKDIQCKDVLLEDVDVSKALIEYVSNAGIEHLVLGSSTKAGLFKKFKVLdIPGIVSKGAPdfCTVYVV--- +>tr|A0A066ZAC1|A0A066ZAC1_9ACTN Uncharacterized protein OS=Kitasatospora cheerisanensis KCTC 2395 GN=KCH_10170 PE=3 SV=1 +SPEPEVAVGFDALEPADAVLEFAFEEAQLRGARVRVVHGWELPPTYGyagwipveserqelgalavgmVSDAVAPWREKYPRTLVLEDVRTGGGAAALVEASA--QSDLVVVGRRSRTLNLGPKLGSVAHAVIHHAQAPVAVVPHD +>tr|F0T9L5|F0T9L5_METLA UspA domain-containing protein OS=Methanobacterium lacus (strain AL-21) GN=Metbo_0511 PE=4 SV=1 +-MFQKILVPINPIEDQDLLVKTAYNLGIERDSEVKFVYFGDDPKAISQLEFYIEKCTQKGLNAsyyfEKFVGTKEEIPEKIAKISE--EYDLVIMGHLKYDKIYRFVHQSTASDLINLVTIPVMIIPDS +>tr|A0A0S3PKE6|A0A0S3PKE6_9NOSO Putative chloride channel protein OS=Nostoc sp. NIES-3756 GN=NOS3756_52310 PE=4 SV=1 +LQFNRWLVPMAGGPNARIAIKLLPALVTLGnEPQIRLTRVFKPLdfqPDMTVLEQAIRQLMRRRqlSSTVIAApVQADSVVEGVIKLVKTEGYDVVVLGASREGLLQQAIQGNIPEAIASGIDSTVILVRGA +>tr|A0A086CIK4|A0A086CIK4_9CHRO Chloride channel protein EriC OS=Candidatus Atelocyanobacterium thalassa isolate SIO64986 GN=ucyna2_00076 PE=4 SV=1 +-KCNNWLIPISYESNAKQILKLLSELIQLYssqnPPKITLCYTFSLNskrLAHKLLEKKAKLLAKKLNCEIFPIfTRSRSTLKTVFELSSTKTYKVIVLGINQKELSNYVVQQKISKLINQHNNSTIVIIKES +>tr|K9YCG4|K9YCG4_HALP7 Cl-channel voltage-gated family protein OS=Halothece sp. (strain PCC 7418) GN=PCC7418_1597 PE=4 SV=1 +-ASQRWLIPLAVEqTNIKPLMSLLPQLSAVGnAPEYLFCTINATEkenPFQ----GTVQQLSKQLQAPVQSLtLPTPTTENQVLQLATEKECDVIVLLttfkaTSPSFSLDTSFENNFPAIVAKRFSGTVILIRPA +>tr|Q8KPT6|Q8KPT6_SYNE7 Putative chloride channel protein OS=Synechococcus elongatus (strain PCC 7942) GN=SED0022 PE=4 SV=1 +LPLRHWLIPLSAQVPQTGLAEPLEQILQLItDPDISLCQIDLPRqtVSANRLQQLQRRLENRLRQPIQADlICARSVTAVLLDVMQSRGIEAVMLSMTLEQLPTTTLWK----DLLAQAPQTVIIQRR- +>tr|A0A075FHV8|A0A075FHV8_9ARCH Cl-channel voltage-gated family protein (TC.CIC) OS=uncultured marine thaumarchaeote AD1000_100_C06 GN=TC.CIC PE=4 SV=1 +------VLSTVGLDQEQTAVAHAtGELFRQSsgakDATLKVIAVESE-----------------------------KTSKIIEQFSQRDHsaDELAILALSRQNFLALIKNAEVRELL--KCQVPIIFSVGQ +>tr|K9SWU9|K9SWU9_9SYNE Chloride channel protein EriC OS=Synechococcus sp. PCC 7502 GN=Syn7502_02411 PE=4 SV=1 +-LSHRWLIVVADCSSPDRAFNLLPHLIAS-DAQVHLCHIFHKPnfeEGL----INPQNLARKLKNPIESTaVCAKSIADAVVDIAKQENSDVIVLITKPHEI----------KQIADAVDCRLIFIGCG +>tr|A0A218PXP5|A0A218PXP5_9CYAN Cl-channel voltage-gated family protein OS=Nodularia sp. NIES-3585 GN=NIES3585_04030 PE=4 SV=1 +PHSPLP------TPHSPLPIPHSPIQPLAShNGWRT------------------------------------------------------------------------------------------ +>tr|A0A1Y0MS94|A0A1Y0MS94_9FLAO Uncharacterized protein OS=Gilvibacter sp. SZ-19 GN=BTO09_09050 PE=3 SV=1 +--MRKILIATDFSKNAAHAAQYAARCFANESVHYHLVYVSDCHSKPgrkppklpckgekcasnriklQQFNVNFQKHLDPKRHRADVHFLDLPPVEALRKMVLKHDIELIVIGCC--SEEKQPQLGRFAQDVIIRVQCPFLIVPP- +>tr|A0A0L0M1W3|A0A0L0M1W3_9BURK Uncharacterized protein OS=Candidatus Paraburkholderia kirkii GN=BPUN_1703 PE=4 SV=1 +-MYKHILVAV-GPGFSESALDTAISRALECNARLTALHVVDQVPWWavvtadcnraqtlaviddharAVTRHSARLIERAGIDGTVRSIElppNASLGETIAKASMALGADLIVLGGEADTGWRHG-GQRLRDAVCARTKCDVLIASP- +>tr|A0A137XH88|A0A137XH88_OCHAN Uncharacterized protein OS=Ochrobactrum anthropi GN=AYJ56_17935 PE=3 SV=1 +SNPRKIMIAWKDSKQSRKALQDAIPWLSQADA-VRLVRIGSPQLLE--IDWAVNQLKEVGV-NCDTVnaplLVDETVGTQLIKEAQKMKADWIVMGAYKYGQTLERLFGGVTETLLSHSPVPLFMAR-- +>tr|A0A0L6JRN1|A0A0L6JRN1_9FIRM UspA domain-containing protein OS=Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933 GN=Bccel_3619 PE=4 SV=1 +MMYKKILIPIDGKKPSEDIVDFICSIQGVTDLEITIIYVIEVPRSLPlhaelpdkvesaryAIATANEIAARHGVNIDTSIIYSRTAEDSILMTAEDIKADVIAIAQDNQ---KLRIFSNMASSIYQRAKCSVWLFNS- +>tr|A0A0D9WGU1|A0A0D9WGU1_9ORYZ Uncharacterized protein OS=Leersia perrieri PE=4 SV=1 +-GRKRVMVVVDQSSGSKHAMMWALTHVASKGDFLTLLHVIPHAGagtggdasAAALANSLGSLCKAcKPEVEVEALVIQGPKLGTVLSQVKKLEASVLVLSQCKPSPFCCFMRSsgeEFVEECINSADCLTLAVR-- +>tr|A0A0Q4B9L4|A0A0Q4B9L4_9BACE Uncharacterized protein OS=Candidatus Bacteroides periocalifornicus GN=AL399_00690 PE=4 SV=1 +---KTIIVPWDSSQGCEYALEHAFQLAQAVGDNVMILQLVKRPGMLltrakrsefeqqlaeqrQQLEREAQRLNMEFAEKRAAIIqnlktktaaagrefqevtitsmvlDYRSLVRSLNELVLTLSVNLFVTSQYYQLSRTTrLDLLPILRkmKSSKVDTTPFIIVNKP +>tr|A0A1F3JS14|A0A1F3JS14_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWF2_40_13 GN=A2W88_12260 PE=4 SV=1 +---DMIIIPWDYTESCELALLHGIQIAKEVNNHIMLARFLESPGFFtgksvkeriiteekEKLRVVGQRIMEQHQINPFVTVELGFSRNHFFKLIRDANANLVISGKTYKVTDKIqFKPKDIVNR-LRGLDIPFIVCQEK +>tr|U5E8J1|U5E8J1_NOCAS Usp family protein OS=Nocardia asteroides NBRC 15531 GN=NCAST_32_08940 PE=3 SV=1 +------VVDP-ASSGPGDALAAAVRAAYERATDVVVIELARPVV---raspengadVEATITELRRRFPTVRISVLSYFGHARTALEKFGG--TAQLIVVPRDP-QALRPFLHGM-ARTALWHTRCAVTVVPPS +>tr|A0A0J8UHU3|A0A0J8UHU3_9MYCO Uncharacterized protein OS=Mycobacterium heckeshornense GN=BMW24_14685 PE=3 SV=1 +------IVA---EADNGGVLRRAFDEARLRAAPLRVIASWRAEAPD-dvgdesrlvqahLTRRVAAWRRRYPDVDVEPVAVRGSICRYLAENAE--SIQLFVSGSHS-RVCELGRADNAGCSVLTVHHDHL------ +>tr|A0A1V4PQI6|A0A1V4PQI6_9MYCO Uncharacterized protein OS=Mycobacterium sp. AT1 GN=B1790_16935 PE=3 SV=1 +------VMAVHGGPDDDRIVDYALNEARLRRAPVLAVDV--------shngdyasdaadLRHRVSRWQEHHPSVHVYPVHAPATIAGFLSQQdDL--RVQLAVLGSAD-VRHVVTILGSDRETGRPTSGCSVLVVR-- +>tr|A0A0F2PH26|A0A0F2PH26_9FIRM Universal stress protein OS=Peptococcaceae bacterium BRH_c8a GN=VR67_03890 PE=4 SV=1 +-MEKQILFISDGSASATKAGAIAIELAATRQSDLRAVFILDEGWGSllgdewintsdtrmkffswfegelktraeQVLNQFSNQAVSSGVK-VETAILTGKTEKVIAEAANNERTVLLVLPNPNSTEPaAAAGLRFNLHHLAKKVTCPILLGPQ- +>tr|F4L4B8|F4L4B8_HALH1 UspA domain-containing protein OS=Haliscomenobacter hydrossis (strain ATCC 27775 / DSM 1100 / LMG 10767 / O) GN=Halhy_3939 PE=4 SV=1 +-PIKSVVYATDFDVANLASIEKMVAWCQALDANLYLVHVNDDPADNAWAKQQMEKImraleEDNEDQRVRFTILEGdDIMDHLEHYMQEVKADLIALTAYRKGFWDRILRSGLAHEVIQEVNIPVLIFKS- +>tr|W2UDX1|W2UDX1_9GAMM Universal stress protein E OS=Gammaproteobacteria bacterium MOLA455 GN=uspE_2 PE=4 SV=1 +----------NHRLLGERVLQKASELATALNIELHVVSVVPDWSQTqaivgpmpgmpgqfptviadmgaqaleHAEDVIRETLVKLAIDSDVIEVRRGFADIELADAVG--DSGALVIGSAAARKLTAkvadKLFGNTSEKVIHHVRGDVLVVH-- +>tr|A0A0S8JE77|A0A0S8JE77_9BACT Uncharacterized protein (Fragment) OS=bacterium SM23_57 GN=AMJ86_07110 PE=4 SV=1 +----RILIVANGSLPGKDVLMFSKQFVQSASEPPTLLTVLNPWMDHppcqnNGITNFAHEDKKYPY--LHSKTVIGQPVEGVIREIKECGYDLVFVGVQGNPLLRRIFHSSSAMRIAELAPCPVVVVKG- +>tr|A0A0N9YTF0|A0A0N9YTF0_9ARCH Putative amino acid permease YhdG OS=Thaumarchaeota archaeon MY3 GN=yhdG_1 PE=4 SV=1 +-IRKNMVILYDDGDNSNEILRVTDYFANSGNFNLIVVA-LNRNTkmINEKKTEFNNTAERkeyksdYLARKEYFKqagvdfneiyvSGE------IEKDA--MQFGKLLLESvlvynPDliitessLGKYSLLSKSKFANLLIYQVRCPVIVVKDV +>tr|A0A151AA93|A0A151AA93_9EURY Putative fructoselysine transporter OS=Halalkalicoccus paucihalophilus GN=HAPAU_36010 PE=4 SV=1 +--PRNILLPTVGGPHAAFIENIATAFTDDERVSLTLLYVDENDTdaVESLLLDRQTALQGsgVNAS-----iaSISATNvSEAIIQFAEAGEYDTIMMGItr--GRILQRSEIGHIAEDVGEQFSGEVLLGKYY +>tr|A0A0T5ZFI7|A0A0T5ZFI7_9ARCH Amino acid permease OS=Thaumarchaeota archaeon CSP1-1 GN=XU09_C0005G0047 PE=4 SV=1 +-ELQNIVVSYDKGRHSNLGLEMANSLSKSLNSNIRIVRGIVES--PEEERDILGIINEkmfdLDMKKIPVErvypktdnaMQS------LLQNFDSGKPEMIIVGAGNqsdqafsPKTMEVVEKSS----------NTVFVIRDS +>tr|V6ARK1|V6ARK1_9ARCH Putative amino acid permease OS=Thaumarchaeota archaeon N4 GN=NITUZ_30058 PE=4 SV=1 +-DFQNIVVSYDKGRHSNLGLRIANSISKSFGSKIRVVRGVVES--PEDELEVMNAINEmmfdLEMKNVQFEkvypktknvAPS------LLEVFDKVESEIIILGAGNqadsafsPKTLEVLSRTK----------KSVMVIRDH +>tr|A0A0S8B0K7|A0A0S8B0K7_9BACT Uncharacterized protein OS=Gemmatimonas sp. SG8_28 GN=AMS20_08270 PE=4 SV=1 +-GPRGVVLPTTKGANAELAAELVPAFGSWFDVPVRAVTVIPSEVpqHEADqfIAEAQETLTTagfpGELKVVRRR---DVV-TGLAQ--LLRVRDLVVMGAp--sTAPIAALFGDTVPAALARRGQHPVVVVRDV +>tr|A0A075WM74|A0A075WM74_ARCFL Amino acid transporter OS=Archaeoglobus fulgidus DSM 8774 GN=AFULGI_00018630 PE=4 SV=1 +-EFRDVLISTIGGPHAKLGYEIARALVEDKSGRIKLLYVGSSEKerEKAEkvFEEAMEILNGLNVERE---FAISSSpSDVVAR--EAESFDLVIVGAse--RTFLKNFLTGLFPEKVVMKTSKTVAMTRKW +>tr|I0A231|I0A231_FERFK Cationic amino acid transporter (Cat-1) OS=Fervidicoccus fontis (strain DSM 19380 / JCM 18336 / VKM B-2539 / Kam940) GN=FFONT_1 +--SKKIIA----------------ILSEDEKYIVDEVKEIFPDReiEEIIiekepnTNNISKTLNE------------------VLS--KESDTAIILMSFniwe-KltkyKWTMKKL---IFPYFVFKRGSFSIDVLRQ- +>tr|A0A1F8YIL6|A0A1F8YIL6_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium GWC2_65_14 GN=A2X88_08585 PE=4 SV=1 +--VKRILLAVEDTLSCRLAINIAPALSEELKSPVTILRTIDPDAgkAEEQgvAAWMEDVIKDlpfrvpVEKQVIRSH---KVA-KTILE--NVRETDLLLMGAsr--hVGAISSLFGTDVTEAVVEKAGVPVLLLKRY +>tr|A0A1J4WK74|A0A1J4WK74_9BACT Uncharacterized protein OS=Parcubacteria group bacterium CG1_02_39_15 GN=AUJ31_01070 PE=4 SV=1 +--LKTILLPCAPGPHLRILGQTAKVIAEAFDSKIKAVFVTTKREaeKSDPEEKLNQCVSAmeipsqipLKTQVLYAEq-SSPRDiAYQIVQ--ESQNHGCILIASar--TRLFHEMIFGNVPEVVTRNSTCSLIMVKSQ +>tr|A0A1G2PKG9|A0A1G2PKG9_9BACT Uncharacterized protein OS=Candidatus Terrybacteria bacterium RIFCSPHIGHO2_01_FULL_48_17 GN=A2806_03865 PE=4 SV=1 +-KRVLVCIPPEGGRHLRYVGRVANSLAGTFGGTINVVGVISPGLpeQQHVaqEQNMLRNIARmrlkvpASVH-----LLRHLSpSQAILE--IEEDFDVIVMGAar--ERFFAEMRAGSVASRVARETQKTAIIVKGH +>tr|A0A1Q7NXL1|A0A1Q7NXL1_9ARCH Uncharacterized protein OS=Thaumarchaeota archaeon 13_1_40CM_2_39_13_2 GN=AUI61_03835 PE=4 SV=1 +-EISNLVVSYDKGRHSDLGLEIAHSFSNTLGSKIRIIRGVVES--PEEERDILSRINEkmfdLDLRKVPVErvyttsldiTKD------LLQNLN-QKPEIVIVGAGNqadqafsPKTIEIVEKSL----------YSVFVVRNS +>tr|M0GAP3|M0GAP3_HALPT Cationic amino acid transporter OS=Haloferax prahovense (strain DSM 18310 / JCM 13924 / TL6) GN=C457_11301 PE=4 SV=1 +--PGRVLVPTAGGANSELADLFAVAYAATGADVTLFHVVTDGDVdtAESFLADKQESLAEseIDVD-----taVQEGEDiAKTILQYARSEGFESVIIGAag--EGILRRVLFGEVPETVGEEFDGEVVMVRKH +>tr|A0A151AAQ8|A0A151AAQ8_9EURY Universal stress protein family protein OS=Halalkalicoccus paucihalophilus GN=HAPAU_30600 PE=4 SV=1 +-MGNSILVPINSIPPTIAALNHVLTLE--GSHEITVLQVCPiierddsirqtvipeaideqreasGQTAEQVFSKATDYAAEHDV-TLETVIDSGHPAERISAYAATNDITRIVIGTQEQSLLSRILRGSLPNAIMKRSSVPVTTI--- +>tr|I7M3S2|I7M3S2_TETTS Universal stress family protein OS=Tetrahymena thermophila (strain SB210) GN=TTHERM_00459310 PE=4 SV=1 +-EFKNLLVAVDGSDYSRKAYEQSLEFLEQKKDQFDQLIIAHITNrnkkylpekmqaetiYDQYKLECDEKFAHNKYKLVFEEKNPNQPScrEQIISLCGQLQISFLFLGFYGRKGVKEqrG-LTQTVSQACYHSKVPLVIVK-- +>tr|A0A0G4G4H5|A0A0G4G4H5_9ALVE Uncharacterized protein OS=Chromera velia CCMP2878 GN=Cvel_543 PE=4 SV=1 +----SFLVCVDASKASVKALQAAMTLSRSKDDKIVIVHLAALDQEslhqdcrkEAVEKKYQAIMVAHmsDMPNVELKIMENTPdmslSRHIVDLIEQDgSFDFVCVGADQMKSRLSdksldnedtWHVGSVSDHVIKHSPCTVVVARN- +>tr|A0A1F3B377|A0A1F3B377_9PROT Uncharacterized protein OS=Alphaproteobacteria bacterium RIFOXYD12_FULL_60_8 GN=A2516_00215 PE=4 SV=1 +SGIKSILVHLAPDQDHMARLRAGYNLCKRFNAHMSVLAINTHPHLPsgsegrvaslsfleqerevaaeknkAMESELDQWRQESEIT-YDWRQAEGDHLEALVEESL--YHDLAIVSQSEPSSLEDMLFVGLPDHLPLLAACPVIVLP-- +>tr|A0A1E7IR31|A0A1E7IR31_9DELT Uncharacterized protein OS=Desulfuromonadales bacterium C00003107 GN=BA869_04910 PE=4 SV=1 +--YEQVLVLLDASDTAESVGKYSVQIAHLCGADMYLLVLEEVPGE---LIDGIRKLGEKGNVHIIEKWVEGNPMIEAVKEVKSGNYGLTVLSWKGTGVIRA----DMIKKIVNDAPCSVLTV--- +>tr|A0A0Q4B8L6|A0A0Q4B8L6_9BACE Uncharacterized protein OS=Candidatus Bacteroides periocalifornicus GN=AL399_02070 PE=4 SV=1 +----TILVPTEFTPECDYALELAVLLAERSSASLTVLHIPEPGEDTAGAQQQLAHFTHEvpNDLPLRVLTVPGEVAETIARVAVDESAEFIVLGSEQVGDPEGQ-KQSETLRIFRYGTVPFIVV--- +>tr|A0A1D2R636|A0A1D2R636_9EURY Uncharacterized protein OS=Candidatus Altiarchaeales archaeon WOR_SM1_86-2 GN=A7316_06470 PE=4 SV=1 +MIVNTIICATKGSEGCKLAENKAIEIAKKNNSKLVFLYVIDIKFMEKssgggewteddvtsglkniggvILDLASEKAVEAGMSqdNVLIEEREGDIASQIKKSVDENNADLVIVGHPAtdmgfleRHLLRRDGMENFINQLKEKIGCEIMIV--- +>tr|A0A181ZDK1|A0A181ZDK1_9MICO Universal stress protein family protein OS=Curtobacterium sp. 9128 GN=GA0004736_2397 PE=4 SV=1 +-QWTSVTLAADAAHPHDEAVRWIAARAGTGIRQVRVVGVDPalegrvGTDGKRVAEHVADETRSAlPGVDVEVVRHAGPAAAALLTESD--TTDLLVIGTFRSRRGST--VGGEAARVAGRAAVPTVVVPDG +>tr|A0A0F9J9G4|A0A0F9J9G4_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=LCGC14_1481290 PE=4 SV=1 +--PKEIALASDFKKsYDASVLLSVRTMANLCGAALRIVHIDEEEKLDDHQKFNLDSLLTFFGPlahSVERIPNFISKTKIIQLFLEKSDIDMLCMVGYEHGLLEKMLREPVIENMVLKIDIPFFIVPE- +>tr|L0DJT2|L0DJT2_SINAD Amino acid transporter OS=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) GN=Sinac_4719 PE=4 +KPKMHIMVPTQGNT---RLIEFAIEECKSRQAELQILFIrhlavtpmgpttiptlAEDEQALQLFERLRTQAHDSGVPLRLLYGVARDIPDAILDMAVTHGANMLLLGLTRRGALWKAMKGDVIQGVAEHLP--------- +>tr|A0A1G3ZK49|A0A1G3ZK49_9BACT Universal stress protein UspA OS=Verrucomicrobia bacterium RIFCSPHIGHO2_12_FULL_41_10 GN=A3F67_06995 PE=4 SV=1 +HHGGPILAAVRGLG---KTLEFAVSEAKETGRPLYVMFVreqlviapgdrkrkwHDDPEAKNIFDTLKEE--GLGDSILPCYAVSDSPPDTIADLASTVGAERVIIGASQRGTLVNMLRGDMVTKLSKLIP--------- +>tr|A0A1J4VRC8|A0A1J4VRC8_9BACT Uncharacterized protein OS=Candidatus Omnitrophica bacterium CG1_02_46_14 GN=AUJ72_04095 PE=4 SV=1 +LYKGSTLVALKTVS---AS---LVEQAVLYvkgktENVIYSLFVeemppgwaypeavEPSKEAIKVLKRAVQEFEKRGITSVPLWSFGDNAGALIVKTAKVLNLGTVMIGTTKRGPVERLLKSQVLKTISDQLP--------- +>tr|A0A1M3CQG7|A0A1M3CQG7_9CHLA Uncharacterized protein OS=Chlamydiales bacterium 38-26 GN=BGO14_04630 PE=4 SV=1 +ATNKSWMVAITGLS---KSLEYALEESQIHQIPLYILFIreqkvvtesdhqknwLDDPEACKVFDYIIAR--EPRMPMEFVYTITAHTAHSVSEIAQEKKVSHIILGRARKASlsFLHVVRGTTVRDLARLIP--------- +>tr|A0A023D1H9|A0A023D1H9_ACIMT Uncharacterized protein OS=Acidomonas methanolica NBRC 104435 GN=Amme_005_008 PE=4 SV=1 +------VIGWRPSAALDKTIAAAMKLL--ETADHVTFLIGDESHEETALPDFARTLEAKGVAvaVTRFQVESGQLGEQIREHALAANADLLIMGSYPRRHFLEWLFGPPTQDMFTRTTLPIL----- +>tr|A0A0R3NCH3|A0A0R3NCH3_9BRAD Uncharacterized protein OS=Bradyrhizobium retamae GN=CQ13_14715 PE=3 SV=1 +-VIRDIVVNLVTSNSRDPAAAYAISVARMFDAQLAGIAMCHSPAIvaggmeavpadlieslheesvraaNGAIERFKQAAAQAHLPAeaQMVETSIEGIPRTFGRIAR--TFDLAIVAQAEPEVT--TSTGLAAEAAMFESGRPIVVVPS- +>tr|E0TFD8|E0TFD8_PARBH Universal stress protein family protein OS=Parvularcula bermudensis (strain ATCC BAA-594 / HTCC2503 / KCTC 12087) GN=PB2503_074 +-AIGTVIVPAFDPKGVQQAVSAALPFVESQGAHLVGLHLREryPASqVpeynwhaavlkefeagvaaraDEIRHAFEVAKGSAD---ATWLQPEGSEGLDFGPALR--AADLIVVPSPKCCDR--PDAAGLIEDILIGSGRPVLLAPG- +>tr|A0A1B1UTK0|A0A1B1UTK0_9BRAD Uncharacterized protein OS=Bradyrhizobium icense GN=LMTR13_34315 PE=3 SV=1 +-MIKDIVVNLATGNSRDPTTAYAISVARMFDAQIAGIAMCHSPAIvaggmeavpadvieslreesaraaNGAIERFKQAAAQAHLPAeaQMVEASIGGTPRIFGHIAR--TFDLAIVAQTQPEAV--TSTDVAAEAAMFESGRPIVVVPS- +>tr|A0A219B3J9|A0A219B3J9_9SPHN Uncharacterized protein OS=Pacificimonas flava GN=B5C34_02240 PE=3 SV=1 +--MRRIIVHAFDDAGFETRMEAAMAFARTYDADLTIMHIRPdfTS--vgepyaaglftgaafaeaeerlkaDERK--FREVADRL-LKGedvtYDWEIRSGLPEREFAREGV--LGDLLMLSPLKDDFSGQA-GDTFVGRMLANATCPVFMAVS- +>tr|E1SMW8|E1SMW8_FERBD UspA domain protein OS=Ferrimonas balearica (strain DSM 9799 / CCM 4581 / PAT) GN=Fbal_2435 PE=4 SV=1 +----------------AKVVRTAMTLSKRLKGQLTLVHSCYTPSFmikyramiqSTHQRVIHDFLAKHHLQRLNWHLLLGEPADTLSDYCRTHQSDLLVMGLVARGLIKKRITGSTTDQLMSERACDLYLIP-- +>tr|A0A126S4U4|A0A126S4U4_PSEPU Universal stress protein family 5 OS=Pseudomonas putida GN=AWT69_002500 PE=4 SV=1 +GQYRHLLVLLTEVDPHSAALRRGLALAQLSGASVHVLGLFTPNQqhllreerlnvaditrqyehYRVQLKGLIERYHGSAIALTVDSLNAEDVRSQAIDYISELRPDMVIKDSEALSAWGRLFGIPLDCALMRGFKGVSQFVPTA +>tr|A0A1H0I0V9|A0A1H0I0V9_9PSED Universal stress protein E OS=Pseudomonas reinekei GN=BVK86_07325 PE=4 SV=1 +RPLRLLFLAPFSQAAHCPGLEYAGDLARALGVPLHIAAFTDLHGaesagpagaecpdvvrqsvlalRQKWLKDESARLQEKGVDVHPEIVRASSSATEFAACAQRLEADLIIKDMQARPGQAHCGLSPQDWEFLSVSPVSVLYVQPG +>tr|G2HX61|G2HX61_9PROT Putative uncharacterized protein OS=Arcobacter sp. L GN=ABLL_1839 PE=4 SV=1 +PEYKNILIPTDLSKSSKKNIEYLVNLF--PEANFHIEHYYKTFFEDrvklygfdedeihdfvdfyatEAEHDLNKFINNLDipkdI-KLFTKAKKFiDIKTMVDESIEYKTIDLLSLSVGSSLSIFSF-------DLLEHSTKDVIIYK-- +>tr|A0A099U6Y7|A0A099U6Y7_9HELI Uncharacterized protein OS=Helicobacter apodemus GN=LS72_07235 PE=3 SV=1 +PDYINAFSPTDFSNNSLKLAKVTKKLF--DNIKITFYHMINRPFEIrlghygaddeqiskynksaeeKAKEQSKKFLKELDKNNVNMVLDSGiLTYTRLLSVAESKNSSLVVLPTSGKVSFFAL-------DVLEHSNLDVLICK-- +>tr|C5ZYG2|C5ZYG2_9HELI Putative uncharacterized protein OS=Helicobacter canadensis MIT 98-5491 GN=HCAN_1475 PE=3 SV=1 +PDYTNIFSPTDFSEASSKIAKITKKFF--PTAHLIFYHMISRPFEIrlghygandeqisnfnqtlenKTKELAKKFLKNFPEHKNEVVLDSGiLSYTRLLSVAENKNASLIALPTSGKVSFFAL-------DVLENSKIDVFIWK-- +>tr|A0A1Q9UHQ6|A0A1Q9UHQ6_9NOCA Uncharacterized protein OS=Rhodococcus sp. CUA-806 GN=BJF84_07570 PE=4 SV=1 +---GRFVVVIDGSPTDTDQVKWAVGLAQRAQAHLEIVHASSVTEWSaamaasletsdypsRIRNAAQQRLEEAvqsaheldPGIEVDSKIVELSAAKMAESISA--DATLLILAADKSGPLRDIAFGHSATTVINAASCPTLVWRR- +>tr|A0A0A5I952|A0A0A5I952_9VIBR Uncharacterized protein OS=Vibrio tubiashii GN=NM22_12210 PE=4 SV=1 +----------------KAIINKSLDIGSRINASTTLIYCQYVAPYlhhyandilTHQKIAINDFLKLSKYSQLPLRLIRANPEEGLPMAVEAVEPAILALGACKRTALSRYWFGSTVDVLMAKPPCDLLLI--- +>tr|A0A061PJI7|A0A061PJI7_9VIBR Uncharacterized protein OS=Vibrio sp. JCM 19053 GN=JCM19053_1549 PE=4 SV=1 +----------------KAIVSRGSKLEQTLSGKMTLVYCRYVAPYlsryraeilSNQKAGITDFISAQKLTRVPLLLPEGNPETALPKAVKQSQAAILIMGACKRSMSSQFGLAAL------------------ +>tr|A0A0A6QSU5|A0A0A6QSU5_9VIBR Uncharacterized protein OS=Vibrio caribbeanicus GN=NM09_05300 PE=4 SV=1 +----------------KAIIDRSLETGAKLNASTTLVYCQYVAPYlnrysqeilANQKHAIKEFLNNNKFYQLPLRLIKANPEEGLPDAVDAIGASILAMGACKRIALSRYWSGSTVDVLLANPPCDLMLV--- +>tr|A0A0C2MYR4|A0A0C2MYR4_THEKT Uncharacterized protein OS=Thelohanellus kitauei GN=RF11_15253 PE=4 SV=1 +-PKRTIIIGVNKEEGSKRALEFYLnVMCDVELDHVYLCHFYEPPplpffsikhplniPWQDWERALRERVETVNKfmnecqwlcerkrVSCTTFTSFTSPHKGLMELAKEVNASMIVIGKKS-NLLEEILGKNVSSYVAHHCHIPVTLV--- +>tr|A0A0C2MI60|A0A0C2MI60_THEKT Uncharacterized protein OS=Thelohanellus kitauei GN=RF11_15252 PE=4 SV=1 +-SRRIVMIAVNKKPESKKVIQLYLdNMCDKDHDLVYLCHIYKAPslstyplsslksiPWQKWEKKLSQRINEINTfmneyqcmcdvkrVPSLVYITYGKRKKGLLELSKILKASMIFMGKKR-GFFSKFFGG-LPVGVAHNCRIPITIV--- +>tr|V6ATI9|V6ATI9_9ARCH Uncharacterized protein OS=Thaumarchaeota archaeon N4 GN=NITUZ_40011 PE=4 SV=1 +TMFKHILVVFVGPKIKAKSFLVGLGIAKKFNSNIFAVDCVYKHPPRfhffetkadkesvakqkakslESLKKLQTFANNANVQVTTKLVLTDAITDWVTDYVKSNRIDLLIMDYPHEPQYDIDLSADIIRAILEKVSVPVLSLRD- +>tr|A0A0D5C417|A0A0D5C417_9ARCH Uncharacterized protein OS=Candidatus Nitrosopumilus adriaticus GN=NADRNF5_1768 PE=4 SV=1 +KIFKNIAVAIITPTHTKKSFDVGLELAKKIGSDLTIIECMYKIQPKlyffetksdkkvaqqqisklkAELEKWKKIAKEQGINVKTKFALTDSISHWVIDYVKVNKIDLLIVDYPKLSMVEMSMYDDIINTIHHESHCHLLTTKP- +>tr|A0A0D8FVB1|A0A0D8FVB1_9ACTN Universal stress protein family protein OS=Ferrimicrobium acidiphilum DSM 19497 GN=FEAC_13910 PE=4 SV=1 +----HLLVPVGSTQDDSAALFWAAaDLANRLELQVTILHCREWDLAKgvkyfmetkdeatSIITSAMKWFSALNIPaqGVLCDVERGSIGKAIATTSTDYHIDSVMVGLRHKRRLLPGLMGSTVTQVERLVNCPVIVIK-- +>tr|A0A133VR25|A0A133VR25_9EURY Uncharacterized protein OS=candidate divison MSBL1 archaeon SCGC-AAA382M17 GN=AKJ55_00305 PE=4 SV=1 +-NLENLLVPVRHPDDVNRVTELASLLLD--RGRITFLTVVEKGSFpssqknwrisSDAIERHSRKFKNRWVEIVPRIRYSDSVWEGVLEQAEIDDSDLILIGWGGKITFRS-LRQTPMERIFANSDRDVIAFKSR +>tr|A0A1Z9BLU9|A0A1Z9BLU9_9BACT Uncharacterized protein OS=Rhodothermaceae bacterium TMED105 GN=CBC65_03370 PE=4 SV=1 +---STVWIVVDFSDTTEPALDMGFRLARAMGASVKLTHIVKPPYEFsgrkesqleagkegarhtlSVIKEDYAAREPYQHIPIELHLEEGSTVATVLSLVKSDPTSLLVLGFEVDESGPRGLFGNITNQLLVESPVPVIAISSN +>tr|A0A1F7N2C1|A0A1F7N2C1_9BACT Uncharacterized protein OS=Candidatus Rokubacteria bacterium RIFCSPHIGHO2_02_FULL_73_26 GN=A3D33_00355 PE=4 SV=1 +-----VVVAVDGARGGRTALALTLAFPWPAGTRVTSVTARRTAATRgrppyvlaavergvRRVAARARRALAQRWPDAAAVLVDREPVPGILAEARRLRAAAIVVGWHSHSAFRRLLMGDVARGVVRGAPCAVLVAK-- +>tr|A0A1M4U5Q8|A0A1M4U5Q8_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Psychroflexus salarius GN=SAMN05444278_102193 PE=4 SV=1 +---MNVLLLTDFSSTANHVMKYASILLRDKPAKITLMHVKKPCSgdscsgkcntiFESKLNKDLKVFKDQNNPlhQLNTHFIEGQYLDSIRDFVKRQDIDLIIVGNSHQHQIEDeIDLDKKTVDVITKVNCPVLLVS-- +>tr|A0A0J5QYD3|A0A0J5QYD3_9BACI Uncharacterized protein OS=Bacillus pseudalcaliphilus GN=AB990_13640 PE=4 SV=1 +RNHEKVLVFLEFDMYSPTTILRGAKVAKAFECDFEVLFLHEAE-NTyhdgpeVELmnTESKKLSEDLGAKHFQIKEFPTYnKAfKHLVSYIKEGGFTQIVLTHVAESRFEEMLHGSFPNLLMKEMP--------- +>tr|A0A061N2C7|A0A061N2C7_9BACL Osmosensitive K+ channel histidine kinase KdpD OS=Geomicrobium sp. JCM 19055 GN=JCM19055_1807 PE=4 SV=1 +PKENHTLVCVQHGKNGLRFIEQALQTIDHTLHHTTIFLFDNMACEEdeahriVGMSLFQKLALKYEADLL-ISEGKPLTNrKLIAETAKEVQATHLIVGQSIESLWRKWIGKSTIDHLSKDIP--------- +>tr|A0A061NSB9|A0A061NSB9_9BACL Osmosensitive K+ channel histidine kinase KdpD OS=Geomicrobium sp. JCM 19037 GN=JCM19037_4007 PE=4 SV=1 +-MTEHTMICVKHGQNGLGFIQEALTHIED-EHRLTIYLFDNMACEEdhehriVGMSLFQKLAEKHSADLL-ISDGRALTTaKRLAETAKEIGATHIIIGEYSEGLWRKFLGRSTADHLTDHLP--------- +>tr|A0A0F4SD49|A0A0F4SD49_9GAMM Uncharacterized protein OS=Pseudoalteromonas sp. S2292 GN=TW82_04610 PE=3 SV=1 +MDKKKLLVLIDSVNCAKTALLHAKQKALQDSKHIDIVAFSYEDTGnilfslspeqvlaiqdkqlsllRATLEPLLKKELTD-CEYTFQTVWHESPEQWLNNEINATNYDMAIKTRHIDAQT---QFSELDWQLIRFSPIPLYLA--- +>tr|A0A0S3AUY5|A0A0S3AUY5_9GAMM Uncharacterized protein OS=Pseudoalteromonas issachenkonii GN=PI2015_1758 PE=3 SV=1 +MDKKKLLVLIDSVEFAKTSLQHAKQKALQGNKHIDIVAFSFEETGnilfslspeqllslqdkclsslRAQLEPLISAELEG-CSYTFQTAWHEAPEQWLNEDINTDDYEMVIKTRHIDSDS---QFSELDWQLIRFTPIALYLA--- +>tr|K6X0G2|K6X0G2_9ALTE Uncharacterized protein OS=Paraglaciecola agarilytica NO2 GN=GAGA_2360 PE=3 SV=1 +MNVSHILVIADRKESLQKAVGHGAILASQFNASVHVAGFCYERLSiladntpkqeldnakqkiiqtsQAWLDETVAESSLP-SSTTDEMVWSKDIAGWVTQHCADHQYDLIIKTGHRSEHA---FYVPTDWHLLRNGSAPLLLV--- +>tr|A4A3Q5|A4A3Q5_9GAMM Universal stress protein UspA OS=Congregibacter litoralis KT71 GN=KT71_16701 PE=3 SV=2 +--MSKILIVADKGK-SCVATSRGLELAAKLGYDVEIVAFVYAPLNridggkteqaelkqqildkrRAQMLERIDAFAKKEQKVALKVVWLKTVHPWIVKRTTNGNFAAVVKTTHATGSL---GYTSTDWHVLRECPLPVLMV--- +>tr|B7RUG6|B7RUG6_9GAMM Universal stress protein family protein OS=marine gamma proteobacterium HTCC2148 GN=GPB2148_3506 PE=4 SV=1 +--MSKLLVIADVKG-DGIATPRGLELANKLGLNAEVYAFVYAPLSrlkvtaaekavikkrllaerEAEVGSRISKFSRDDQKVKLKVLWEKDVADWVSKKCSKSNYQMVVKTGSQTESF---AHASADWQLLRECPAPVVIV--- +>tr|D1CB38|D1CB38_THET1 UspA domain protein OS=Thermobaculum terrenum (strain ATCC BAA-798 / YNP1) GN=Tter_1087 PE=4 SV=1 +---MKALVPITGQEEEEQIIEMLRSLPK-SIEELIVLHVQDPSPektfemlelghhhiskyrleevqktqeayAQQAVNRAIDTIRRYVNILATGIILKGRANEEIMRAIQKEGAELVILFAKK-NASGPKSIGKTARFVLDHAPCSVLLIR-- +>tr|A0A0D6YIB7|A0A0D6YIB7_MASLA Universal stress family protein OS=Mastigocladus laminosus UU774 GN=SP67_12755 PE=4 SV=1 +----NFIVGYNSSPNSHTALDISLLMAHQTrlatnsHVLVQAVYVLEEYYTndffdisptqefqtsesfeqfstycpinlpsknvqtpvltqtnkfaqaERILWQARCLAEEWQSY-FKAHLRFGCVADELKKVVASEAATILFLGCKSAKHP-------IVQKLGSNFPCSVVGIPTC +>tr|A0A1Q4RDM2|A0A1Q4RDM2_9CYAN Uncharacterized protein OS=Calothrix sp. HK-06 GN=NIES2101_36560 PE=4 SV=1 +----KFIVGYNSSRQSHTALDIALCMAHQArlasnmQITVQAVYVVEDNQScyiqetyssihqpvyadivstsvltearlkseclmimeqtDAILCQARSLAEEWQVD-FDCLLRFGCAASELKQIVELEGADVLFLGCNSVKHP-------IIKSFGADLQCTILGIPSS +>tr|A0A1Z4QPH5|A0A1Z4QPH5_9NOST Uncharacterized protein OS=Cylindrospermum sp. NIES-4074 GN=NIES4074_46240 PE=4 SV=1 +----NLIVAYDASPNSHTALDIAFWIAHQTrlatnaQVSVQAAYVLEDNPRklysdifsveqdplplecsvsdvsksvtlvltqpkltavatnlpgesltpikqaDRILWQARSLAEEWQGT-FKSHLRFGCISTELKKVVESEAADILFVGCKSADHP-------MIEKLGANFPCAVVGIPSC +>tr|A0A1F3XYJ6|A0A1F3XYJ6_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium RIFOXYD1_FULL_55_31 GN=A2603_13585 PE=4 SV=1 +RKFNSVLVPMSGEIRTSHALTLGIKLASEFAVPLDLIYVVDPETvseecpcpllsflddayheYPRMLEELIAEASpltsiEEKASIRDFHFCTGEAAREIVNQMKKRHTSLVAIEWHGRLTRGHA---RVLKHILRQAHCLILLVKTE +>tr|A0A1F3Q5G3|A0A1F3Q5G3_9BACT Uncharacterized protein OS=Bacteroidetes bacterium RIFCSPLOWO2_12_FULL_35_15 GN=A3F72_05235 PE=4 SV=1 +-----ILTALDFSKCSDNALNYALKSYNDYNAKIIFLHAIQSGYIETNIEKLVDKdpkitkhnienklqtiiskkiKKYKSKCDYEIITEFSLPLDLILKTLHKVKPFFILLGSKKTISFVQNFFKNDTIKIIEQAKCPVIVIPEG +>tr|A0A1Y0GZE1|A0A1Y0GZE1_9BACT Uncharacterized protein OS=Armatimonadetes bacterium Uphvl-Ar1 GN=CCB80_08300 PE=4 SV=1 +---MRILVGIDTMQAWQGAANLLVRLFPD-GFEAELVHCIESLLPDssfpsvsldhpiatiyqefrrqgqEALDLATAFLSQHNVQ-CHQSIREGNVRNVFTEIAEKSNCDLIAIRSSIKSPSESLIFGSTAKALVLSANIPLLIVKNE +>tr|A0A099Q1T2|A0A099Q1T2_9XANT Uncharacterized protein OS=Xanthomonas sp. Nyagatare GN=NC00_07525 PE=4 SV=1 +--PTHLIFATNFSETCHAAIPTVAQLVDRLRARLTILHVHAKGKRAQARQSLDAFFAEAsNYPGCERALASGPAAAGIVSFCRSRDDALLIMPPSERTGLPRPLHVSLRARVLERVATPMLTLP-- +>tr|A0A0Q5GH87|A0A0Q5GH87_9XANT Uncharacterized protein OS=Xanthomonas sp. Leaf131 GN=ASF73_07840 PE=4 SV=1 +--PTHLIFATNFSETCHAAIPTVAQLVDRLRARLTILHVHAKGKRAQAQQSLDSFFAEAsNYPSCERSLSSGPAAAGIVSFCRSRNDALLIMPPSERTGLPRPLHVSLRARVLQRVATPMLTLP-- +>tr|A0A1G3Q770|A0A1G3Q770_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWF1_49_6 GN=A2014_11450 PE=4 SV=1 +--MQKIYIPICGATEAKRAIQKGIETAKRFDLEVVVINVVDQESInklqrykifideesamftdslkrdaEKYLHYAEKIAEQTGI-AVTKVLLEGDPFSEILEYIKNDSADikLVCIAKRRESQDCRDLFGVVERKLLSQTDFDLIV---- +>tr|W5WY28|W5WY28_BDEBC Putative universal stress protein OS=Bdellovibrio bacteriovorus W GN=BDW_04870 PE=4 SV=1 +--LKTMLFASDFERTTTKDIEHILSICKSLKANLVVFHHANisykepsqesspkSSAYRRKVNEMKSWIEITSKKskvscEVLVKSDFKSVTEHIKSIVKTKKCDLIFVRAKA-SAKKTLMGGSITRAVVRESTLPVYILKN- +>tr|A0A0S2HRI5|A0A0S2HRI5_STRVZ Universal stress protein UspA-related nucleotide-binding protein OS=Streptomyces venezuelae GN=AQF52_6940 PE=4 SV=1 +--MRGTM--ICGTPRRIGTVSFG------RQLPTSARPSYPESyeTETiamvpvftvsldgwakRLVHQEQTHLKELvPGLANAGNPVADDARNAPQRVAS--ESEQTVLGSLGLTPAVS----SASPAVVARAARPEVLVRGE +>tr|A0A0U5J571|A0A0U5J571_9GAMM UspA domain protein OS=Thiocapsa sp. KS1 GN=THIOKS11770032 PE=4 SV=1 +--PRRLLIPVTERPDGFRSGMPFLRLFAPQVTRLHIILIARVGRRRflrmshegaerllgpgqayceRVEKEIVEQLGLGPEVMDAQVVVSDQVAREILIAAHRTKSRLVYLGVSERHPAERFLYGDPVEQVLRDASCDVAIYRG- +>tr|A0A1B9ZBL7|A0A1B9ZBL7_9BRAD Uncharacterized protein OS=Bradyrhizobium paxllaeri GN=LMTR21_11820 PE=4 SV=1 +---MRLLAVVDSTESTNRIVDFITAFSEgRAATEAVVLNVQSKRLDARlrgyqnfkkdeiderlinefafpILNSVTGRLEKAGIL-CSSKAEIGDPVTTILRCAAENACNVILVGAQPSKGFDSWlpntmrvwLRSDLALRLIALAPASIVVVK-- +>tr|A0A1G1FV62|A0A1G1FV62_9BACT Uncharacterized protein OS=Nitrospirae bacterium GWD2_57_9 GN=A2010_10945 PE=4 SV=1 +---MKILTLYDGTMQSKAALRYGLRKVREKGGSLTVLQVFQTDLFVDydagpraqdiaraesarHRRDAEAIISAAGNEgiSVNVRSEEGEPVEEAARVAESEQPDLVLASPRYKA-------------LVRRTSRPVYIIPGT +>tr|A0A0F9XLD2|A0A0F9XLD2_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0202220 PE=4 SV=1 +QAIRDIAVHVDGSDGDAAKTSHADMIATMFDAPLIALLMNYLQAAPippgpgrswlnaelrkrgveqgdAAEIRARERLAGLRA-PSEIRRIDYAYQelgARIGPPAR--SVDLVVVGRPHG---DGGQWPEMFEAVIFDAGAPAYVVPPN +>tr|A0A0F9UIU0|A0A0F9UIU0_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0216880 PE=4 SV=1 +HGIADLAVHLDGGNQDAAKIAHLQTIRAIFGAHAEAFFANPIPTAFipigpgyeglpaeiwaegaaagdVAEKTIRARLDKLDF-AVELRRVDGMPHelaPATATLAR--SLDLFLLGRPNG---DR-WLADILEAVLFDAGAAALVIPPD +>tr|A0A165Q8D8|A0A165Q8D8_9RHOB Universal stress protein family protein OS=Pseudovibrio sp. W74 GN=PsW74_03445 PE=3 SV=1 +MSIK-TVVTLTDTSGDQVASRVAVELSKLTDAYLIGVVPNYEtSYYLctagpmppdyelrlqeqsaatlnKSLEGFAKHFDGAGI-DGETRVTDITLGgtfDELMHLGR--LSDVTVIRQDDPA-KPEPMRAAMIEAMVFDTGVATLIVPHA +>tr|A0A1B1AH29|A0A1B1AH29_9CAUL Uncharacterized protein OS=Caulobacteraceae bacterium OTSz_A_272 GN=ATE48_07915 PE=3 SV=1 +MVWRDILVFADGSQEGLSRVALAHNLAHRREAHLEARLITLAPEPPlgetsfaveravaalrqaaheraMSAVRAVEEMEKPGQ-RFSVYHDECSWGevaHLGAAAAL--TSDLAIVAQPREG-RDGDLDRRILEAALFRAGTPCLIAPPW +>tr|A0A0R2VI64|A0A0R2VI64_9SPHI Uncharacterized protein OS=Sphingobacteriales bacterium BACL12 MAG-120813-bin55 GN=ABR95_09185 PE=3 SV=1 +-PFQKIIFPFECTAKDLDIIQFCIKLAEIFHSTIYLIHFLLEGAVInkTILDKINTRFHKEiSEERLQIHILADkNITGGISKFAERVSADTVVMVTHNRGLMATLFHMSTTRKMVLYNNTPLLAFKAE +>tr|A0A1Q3W9B1|A0A1Q3W9B1_9BACT Uncharacterized protein OS=Spirosoma sp. 48-14 GN=BGO59_25445 PE=4 SV=1 +-PLRTIVYASDYLPGDIDNLQKLVPIAQAFNSNITVIHITRDESDEavKTLADFEQQVNAEvGPSNIRFRLVKGtSVEKTLEQYLDENKVDLLVMSAHQRSLPEKLFGKSMTRIMTLYSHISLMIFHQK +>tr|A0A1Q4F3Y2|A0A1Q4F3Y2_9SPHI Uncharacterized protein OS=Sphingobacteriales bacterium 44-15 GN=BGP14_16920 PE=4 SV=1 +RMPAKVVLTTDLKEVKeKISSSSIFKFLDAIQAKLLVVNVARKDKDVSHLRTEIMDLHSllDRYTPEIHYINHPDTIEAIDEFAQHHQAGIVITFHEQQNRPAALFHKSVSKKLAWHSRLPLLVIP-- +>tr|A0A1V3MSD1|A0A1V3MSD1_9SPHI Uncharacterized protein OS=Sphingobacterium sp. CZ-UAM GN=BWD42_24440 PE=3 SV=1 +RIPRKMLIATNLKEVKlKLDRLLINAAEVLRKSEVYVVHVTKEDPASKAVRTEINLMNEllASYHPIYSYILHSDIAIGINQYINENHIDMMVTFHRDKGLLSRIFNTSIAQKMAWKSQAAMMVIP-- +>tr|A0A1G1FV62|A0A1G1FV62_9BACT Uncharacterized protein OS=Nitrospirae bacterium GWD2_57_9 GN=A2010_10945 PE=4 SV=1 +--PGTILVPVDSSETVKADRDMICAEARETGSAVLFLGVVPVHLYSsaerdeleqvrkktaSVIKSVQKWLGEQGI-KASEVFRAGYPDEEILKAAEEFSVSLIMLPAGGKTPSELAKAAAILLDEPERVKRPVYLMPA- +>tr|A0A1G1FDT1|A0A1G1FDT1_9BACT Uncharacterized protein OS=Nitrospirae bacterium GWC2_57_13 GN=A2X56_05655 PE=4 SV=1 +--PGTILIPVDNACAAPGTVEYVAREAIATASEVVVLGIVPVHIYSssekkelaavkkrtaDCVRRTKKLIHERGI-PVTDAIRAGFPDEEILKAADIHDASLIILPAGSAVPSELSKAASVLLDEPHRLRRTLFLVPA- +>tr|I0INM1|I0INM1_LEPFC Putative osmosensitive K+ channel signal transduction histidine kinase, sensor subunit OS=Leptospirillum ferrooxidans (strain C +--YERITVLVSeHTPSLERLVGYAGNLSRRMGGELLVLHLRKISflgkrspPDQEILSRFQQEARGAGGKFSILW---tRNPGWTLWRFIQRTKTTRLVMGHAGTQSP---WRKSLVRSVLRYFSrIDVEIH--- +>tr|E6PCU7|E6PCU7_9ZZZZ Putative Potassium-transporting P-type ATPase D chain OS=mine drainage metagenome GN=CARN1_2168 PE=4 SV=1 +--AERVSTavtFVPAIPSAQAYVERSAAVADALDLALEVRPLGDAD-----IADLNDAARRNNAELLSEPIDPaT------IDLE-RVRASLLI-----------VPRGAFARRIVNHALeRDVFVI--- +>tr|A0A0C2A3G0|A0A0C2A3G0_9DELT Universal stress protein UspA OS=Enhygromyxa salina GN=DB30_02346 PE=3 SV=1 +-----MIVPYDFSAHARRACALAMQGFPfGMDAQIEMLHVIDADLYAnvlahkhvpdddaidsylaDELTRIHAELAVAHAKhstpprllEPKRVIVRGRPHASIDARLHEPDVIGGLLGGQGHGGATEKLLGRTAQRVIRHASVPLLVVKR- +>tr|W5Y4M6|W5Y4M6_9CORY Uncharacterized protein OS=Corynebacterium vitaeruminis DSM 20294 GN=B843_12195 PE=4 SV=1 +-PVSRITCMYDPQHGDFQLFRYALERAIEMGVELRVVTLDVGDDIKgspgahpdaanslRRLGIDVDGLVRGGH--LSFLKATGQNTPRAIAELTWREGEVTMIGSTREAADGRVSAGPFATKLISYIPTPIVMATA- +>tr|A0A0B8YKB4|A0A0B8YKB4_9SPHI Uncharacterized protein OS=Pedobacter glucosidilyticus GN=PBAC_04690 PE=4 SV=1 +--IKNILVPTNLTVGSLSVVQYALHQFKGYAFNITLLHVLPLPDAisdllmlsrksdenehiPAEFHAAVQRLTLLfplRISSIQIEHQYGLSASILSQIITSKEIDLIL---HCKTVFKSAAnsDEQKLLKLLDESAYPVLYVPE- +>tr|A0A1M6V3V6|A0A1M6V3V6_9BACT Universal stress protein family protein OS=Hymenobacter psychrotolerans DSM 18569 GN=SAMN02746009_01489 PE=4 SV=1 +--MKRIVIPTDLSLYSVHLIRYALNLLQGQTCHITLLQLTPLPDSitdlltlprpdraplerNPEFGKAIARLQRHyalEIEAIQVAHLYYDGAQQLKQYLQELSIDLVL---APVPLTRPAKGAAHLHRLLTNAPCPVLYIPE- +>tr|A0A0Q5W5W4|A0A0Q5W5W4_9ACTN Uncharacterized protein OS=Modestobacter sp. Leaf380 GN=ASG41_17495 PE=4 SV=1 +RPRPWILVVVEETDADHGALVWALREAARREATVVAVRVLDDAAdgplldgltlpagdahTAALDDAVLRAVVETGIQgRTRTAVLDPHVFAALTGAAR--GADLVLMGGRGKTLLRR------------------------ +>tr|A0A0G4H4U6|A0A0G4H4U6_VITBC Uncharacterized protein OS=Vitrella brassicaformis (strain CCMP3155) GN=Vbra_10573 PE=4 SV=1 +----TFFVGVDGSEASHQAVDLVMKYSMpKSKNRMVVAHVYDESKTYlprpmqqaVLLAEMENRLitsfpaARYELK-WTAKRPEHGIKEELVHSANETMADFVVVGFYGRkgRKV-DHSIGSSADYSMRNASASSIVVKDT +>tr|A0A098SAQ1|A0A098SAQ1_9BACT Uncharacterized protein OS=Phaeodactylibacter xiamenensis GN=IX84_10050 PE=4 SV=1 +-QPKRIAVSLGSRLNLNLMVRLAGALATQFGGTVTFLNILPKDFTAAQQAEsGKIFIEAIQRHSARAlyntqVMASDNPIDTLVEKSG--EFDILIVGTTKVGFLQRMVVGNFTTQLTERAHCSVAIVR-- +>tr|A0A098LIS7|A0A098LIS7_9BACT Uncharacterized protein OS=Sporocytophaga myxococcoides GN=MYP_3588 PE=3 SV=1 +RPLKTIVYACAISVRDHNNINELSEYAKEFDAEIIILNVRDklEQEYPEIAAVMLDEIMDHvHYKNIKLITKTGTNVSAIIKkFIDEIDTDLVVMATHHRNFLEAILSGSTTEKVLNISSHPMLIFH-- +>tr|A0A1F4EZL4|A0A1F4EZL4_9PROT Uncharacterized protein OS=Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_67_28 GN=A3F77_05940 PE=4 SV=1 +NAMLRVLIPVDASRNCQFAVKHVISQFMNNTAmEIHLLNVRPPFSShiarfvsrkarhdyhrdegEKALAPVRQMLNNFGI-PHAAHIELGDKAKIITDAARRLRCDQIVMSTARKNSLTRLVESSVTNRVLELTTVPVEVIAGD +>tr|W7QJR7|W7QJR7_9FLAO Uncharacterized protein OS=Cellulophaga geojensis KL-A GN=KLA_10533 PE=4 SV=1 +----KILVLSDLKKTTVSTVKSTVNLAKMINGDVSFFHVKKASDVvvrdnqlsamraineqynstDRIISAIIKPISKVQNIKIKYSFSFGNVKNEIAKQIEEQQPDIIVLGKRK-PKMINVIGDHVTDFVLKNYKGVIMIAAND +>tr|A0A0F7PBM0|A0A0F7PBM0_9EURY Uncharacterized protein OS=Halanaeroarchaeum sulfurireducens GN=HLASA_1055 PE=4 SV=1 +--MGTIFVAYGGPGNKNAVLEFAVEQAAASEHDLLVYHVLEDEQEsSQEIREEVERVVESVDPSVTYEVqfntrsevsdrtnisKQKRLTSAIQESDR--DYEYVVMGCVERPTIEGIVHASMTEAVLEMHSTPVMLVP-- +>tr|M1WY31|M1WY31_DESPC Uncharacterized protein OS=Desulfovibrio piezophilus (strain DSM 21447 / JCM 15486 / C1TLV30) GN=BN4_20026 PE=4 SV=1 +MDMLKALVPVEMTLASNVALRYLCQKSDLLGIGVQPIHIEEPDHKrhssqtgwirkswesglrQAGLEEVRRILKSEKLDcfvLPNPIIRVGSREDKILEELRLGWYDLFVEGELA-NFNTGEFRKRLRSRFYKQMPCPVLIVRN- +>tr|A0A239JW64|A0A239JW64_9BACT Nucleotide-binding universal stress protein, UspA family OS=Pontibacter ummariensis GN=SAMN06296052_12421 PE=4 SV=1 +KGLKSVVFAADLAKSPAVAvLDSLRDYLKAFRSTLQVLYLYSKDQQQAEQEKSLAALEDmgKAFSDLDYRVtfqQREDTAEAIKQFIQEQQADLLVLAPQKRGFLEDLLNKSVTQRMMAKTFIPLLALPPL +>tr|A0A142HM76|A0A142HM76_9SPHI Uncharacterized protein OS=Mucilaginibacter sp. PAMC 26640 GN=A0256_00405 PE=3 SV=1 +KEIKHVLYASDLTDYESE-LAKVVAFARPIHASVDLMHISYPFEFAFDKELMEATLKKKADYDVTIVKRQRDITNALLEdiddAIKVSKPSLLVLFTHQsRSMFEKLFYPSNAEEYSFYGKIPLLTFN-- +>tr|A0A0B8YEI5|A0A0B8YEI5_9SPHI Universal stress protein family protein OS=Pedobacter glucosidilyticus GN=PBAC_10000 PE=3 SV=1 +RDIESVLYASDLINLDKE-LDQVIDFAKPIDAKIEVVHFGFPSDIAKKVKLAEEKVKNHSDYPVEFHVQPSDFIKSLVNnietAVKRSKPSMLVMFTDQkISFFKKMLFSGNTEEFALNTRVPLLVYP-- +>tr|A0A1G3J2N3|A0A1G3J2N3_9BACT Uncharacterized protein OS=Sphingobacteriia bacterium RIFOXYC2_FULL_35_18 GN=A2472_04910 PE=4 SV=1 +KAIKKITYVSDFENLVTE-LSKVTKLNSLLKGQTEALHYARMGVNHPDTLKKIKIFSKANYIGIKPNVLETNIEYSLVDrltkYIGKQHPDLIILFTRQkKGFFEQLFLPSKAAELTFSTKIPTLIYP-- +>tr|C4FLJ6|C4FLJ6_9AQUI Uncharacterized protein OS=Sulfurihydrogenibium yellowstonense SS-5 GN=SULYE_1450 PE=4 SV=1 +-EITKIFINFQFNNISLKALEIAKDLANKYNSQLIIFHEIEDVYMMkkiaasfglpvppdleeknktSAKSRIEDLLTNFSNDVKIIVDISESVKNSLPKFIKEESPDLVII---------------------------------- +>tr|A7I3R2|A7I3R2_CAMHC Universal stress protein family OS=Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A) GN=CHAB381_163 +---MKVVVCIKNNQICDNVRDYGIYVAKILKSQISFVAIMENQELgdsfyglaaggivlgekdmilsnyqnleqenneetlkkiQEYLDKCVKKANLEGLKAEQT-LKKGDFIDIISTYKN--EADMFITAARYD---ESDDIDFNANMLIKELKVPVLLVNKE +>tr|A0A0A8H016|A0A0A8H016_9PROT Putative universal stress protein UspA OS=Campylobacter insulaenigrae NCTC 12927 GN=CINS_0260 PE=3 SV=1 +---QKILVCIDILEPCKNSVDYGIYFAKKLNLPLMFLYVVESNFTntelacsfgigssgcviedlveeqtqknenlckesKKILKELSLYAKDKGVAECFGVQRDGDLEEILKDYDG--KMRLVIAGLKGNG--EKQKIGKHIEELVRALNVPILLINSA +>tr|A0A161SI63|A0A161SI63_9NEIS Uncharacterized protein OS=Crenobacter luteus GN=AVW16_08365 PE=3 SV=1 +-MLKNLLLVLDAGPIAEQARELALSLAQTHGAGLTALSLIDTAPLHageaapaggsaflearnakweaewlegarERIVHMREAAAAAGVTVSSVLAEDDQPDVALLNQAR--MHDLVVASSDCHLGAESrPHDTHWLSRYLADAPRPLLLLTPA +>tr|E6VEH0|E6VEH0_RHOPX UspA domain protein OS=Rhodopseudomonas palustris (strain DX-1) GN=Rpdx1_2411 PE=3 SV=1 +-MLKRTLILLGQTESSVSARDYAFRLAQRTGTDLAGLAGLDLRSIEtpmlggigtsaykaqleqelksqaeatrQRLHEEFERECRERALPFEWLSFEGDPIEAFQLATE--TRDLVVAGHDTGYGGDLtEPLSEILAKLLLRSPRPLIVCPDR +>tr|A0A0M9UDA6|A0A0M9UDA6_9CHLR Glucosyl-3-phosphoglycerate synthase OS=Ardenticatena maritima GN=ARMA_2221 PE=4 SV=1 +-EVKNILVPIRGSKESALLIETALALTEALNSRITLLFAEESQSEErdEAIWQEIERSTRGHRLVTRRLRVIGDVVSAVRQIAG--EYDLIMVGVaEQRAGSGARRVGAIARGITEAVNTPIILVKTE +>tr|A0A1Q3SN51|A0A1Q3SN51_9CHLR Uncharacterized protein OS=Chloroflexi bacterium 54-19 GN=BGO39_26475 PE=4 SV=1 +-PIKQILLPVRGGSYSTLALSLVSNLAEEWSAGITVMHNLGNNSGLadSFrpsQAQSFSAFSDGYEvedeslttlqalalelpPNAKLVAMQGKLIQGIVQEAH--HHDLIVVGAsETRERMDEQASGeKIAEKIARETRRPLLVVKTA +>tr|A0A0E0N3D3|A0A0E0N3D3_ORYRU Uncharacterized protein OS=Oryza rufipogon PE=4 SV=1 +SPHRRIAIAVDLSDESAYAVRWAVQNYLRPGDAVVLLHVRPTSVLYgadwgsipvsvsddadgevapaasaeelqkkreedfdaftsTKAEDLAQPLVDAQIPFKIHVVKDHDMKERLCLEAERLGLSAMIMGSRGFGASRKggkGRLGSVPTGRQQGqqMSCTLCLR--- +>tr|A3DKX5|A3DKX5_STAMF Uncharacterized protein OS=Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1) GN=Smar_0172 PE=4 SV=1 +-NIKKILIPAIKNEIISFATEYGITLF--PDAVYHLVSVIPSMKRrslytrlyvgsfrkiaEDAFQDIEIVLNKHDCTAIKKAILKGNPVKEIRKYVKQYKIDLVIITSSATPTPPPKLIGSTATKIIGSLEIPILIITP- +>tr|N6V2C7|N6V2C7_9RHIZ Uncharacterized protein OS=Rhizobium freirei PRF 81 GN=RHSP_54571 PE=4 SV=1 +MNFRTILAPIGVNH-LEKDLRQAIVFSEAAQAHLSILVVAMAAPPPvggygefvsaawleeregdltklaDAVETAKASLSqsGLSYDVQDLYTEYAWAGEDIAPCAL--YADLVLVGAGAA--ADVQFSKRVIDGALFQSPTALLFNPTD +>tr|K0Q5Y1|K0Q5Y1_9RHIZ Putative universal stress protein OS=Rhizobium mesoamericanum STM3625 GN=BN77_p10193 PE=3 SV=1 +MSIKTVMCVFGVDR-WDQDVKSAIEFCETQGAHMTALVICMGSVPAiatyeaisttwlegqqkeidrlaDETKAVREILErtELSFDIQEIYTEFAWADDDIAQHAL--YADLVLVGAQAA--GNEDLQRRIVDGALFESPTPILINPRT +>tr|W8RPI4|W8RPI4_9RHOB Universal stress protein family protein OS=Roseibacterium elongatum DSM 19469 GN=roselon_00641 PE=3 SV=1 +MAYKSILTVLTDDKDVAPVLDAVAPFAAAAEAHLDVLCLGIDr-TQTgyyfagattlmhdetlaqaqaeatRIEQAARTHLAqsDISWGVEALVAQSASVTPVVARRAR--FADLVMLPKPYG--ADLpSDAPVMVESAMFQGNAPVIVLADE +>tr|A0A0Q7VAT4|A0A0Q7VAT4_9RHIZ Universal stress protein OS=Mesorhizobium sp. Root552 GN=ASD50_05125 PE=3 SV=1 +MTFKTILTVAGPESSCEGDLKLAADLCEQAEAHLSVLVMTLAAPPPigeyaavvsdswlqereadlkhlnARKAEISTFVAgsAVSGNVVSEYPEAGWAEEMVGRRAR--YADLTLAGPELL--KTETLKEKVIEGALFWSGKPLLLVPEG +>tr|H0HDV6|H0HDV6_RHIRD Uncharacterized protein OS=Agrobacterium tumefaciens 5A GN=AT5A_19281 PE=3 SV=1 +MSVKTILAVIGAHD-AAADISQAIDLARELDSHLSILVLGAALSPVtadypvttvwleerqneidelmKIRKEAENLCNinGVTYDVDQLYEDRFIIENNLCMRAM--CADIVVAGNGIR--KDIDLRKTVMAATIFDARSPLMFMATQ +>tr|A0A1M3A4J9|A0A1M3A4J9_9CAUL Uncharacterized protein OS=Brevundimonas sp. 67-6 GN=BGO02_16050 PE=4 SV=1 +MPWTSLIVYVDDEADNPARLTE--ACALAG--AHGARLIGvsaCAp-ETPvadaygagillgevmaaqqarnettlkSAEQRFRGAIEaaGVEGEWRGDVGDP---TGLTLRHLR--AADAALVGRDAG--GAsawraPhpadl----------AMRAGRPIVVLPPN +>tr|A0A1Q5PJB1|A0A1Q5PJB1_9ACTO Uncharacterized protein OS=Actinomyces sp. VUL4_2 GN=BSR29_08315 PE=4 SV=1 +---MSVVLGYFKNPESEQALQTAMALASQEQLKLHILAPTPNDNHeiEAENQALWEQVENTEI-EFEVHRVAGEAElsKQILALAQEQQARYIVMGIQS-AAAGAVQIGPNARQILLNASCPVVTVTAN +>tr|A0A1S3XTP0|A0A1S3XTP0_TOBAC uncharacterized protein LOC107768687 OS=Nicotiana tabacum GN=LOC107768687 PE=4 SV=1 +NSTRKVMVVADPTRESAAALQYALSHAVAENDMLILLHVGNPNAWrnllgsiikkplpnsatssfsstststtslpsqseegrgihnnpfgaffkkslasyasppsssmlsnvaedggvrgcggkgyMDFLGTMKHACEVAQPKikvCTETVEMDGNAkekASIILAKAASLGIDVLVIGQRRSLsnvILRPRRSVSlrglgldMAEYLIENSKCTCVAV--- +>tr|G7L828|G7L828_MEDTR Adenine nucleotide alpha hydrolase superfamily protein OS=Medicago truncatula GN=11426587 PE=4 SV=1 +NQSRKVMVVADPTRESAGALQYALCHAVMEQDELILLHVIEnTSSWrntlstflkmpslgtsttaslndiggggggggggggaaagggagggsaaegetvVDFLEEMKNACKAAQPKlkvRTMKVEIDN--gkdrANTILLHTLDQRVDVVVIGQKRTLsstLLGYKRPTgGslkgvkmfdTAEFLIQNTpgTCTCVAV--- +>tr|M0BEV4|M0BEV4_9EURY Formate/nitrite transporter OS=Halovivax asiaticus JCM 14624 GN=C479_11395 PE=4 SV=1 +----RVLVPISNPRTERDLVELACTLAGSReSGAVHVVHFVQAPEHgafhgdpeqhdrivdasERQLEAFEPMGEHHDIEFQTSTVVTPRSFEDVFDTANRLSPDLVLMGWGRDTVWSSARAERPLDELTNQLPTDFLIVRD- +>tr|A0A1H9YVX4|A0A1H9YVX4_9EURY Formate/nitrite transporter FocA, FNT family OS=Haloterrigena hispanica GN=SAMN04488694_101269 PE=4 SV=1 +----RVVVPIANPRTESTIVDLACTLASSHeNATVHAVHIVQMPGRasmrygagqtdrivsesEQRMETVRQRARSYDVDYETSTVVSHRSFEDVLHTAERERADLVVLGWGDDRPWGKGRAEGRIDELTSNLPCDFLILKD- +>tr|A0A088F480|A0A088F480_9SPHI Uncharacterized protein OS=Sphingobacterium sp. ML3W GN=KO02_18485 PE=3 SV=1 +-KMQSILIPTDLSSNFSKVKNKVEDLLPTGSPfQVSIIKSFNIPSVFfpfiddqetkvkaeklimVQYEALKKKLKISDTWSFKAVYQNGkSISDIILRENKNCRADMLVMAAKGASTIATIFLGSTTNEIINRDPFQVLYI--- +>tr|A0A1M5GM13|A0A1M5GM13_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Flavobacterium segetis GN=SAMN05444396_10410 PE=3 SV=1 +-SWDRILVPTDLSAMFRTIHAKMEVLKRINPPvNFRIVKSFNIPTVFfpyidiedqkvikeaekhinKQFIDAKKKYKISDDDVFVAVFRGKnSIVEIIKKESKAFNADLILMSAKGDSSVSSILIGSTINELINSAPFKAIYI--- +>tr|A0A0E0VS00|A0A0E0VS00_STAA5 KdpD OS=Staphylococcus aureus subsp. aureus 71193 GN=ST398NM01_2120 PE=4 SV=1 +---PHIAVAISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFEISrqykdsQKQVHQHLMLAKSLGAK--VKVVYSQTVALGLDEWCKNQDVTKLIIGQHIRNKRRDFFNKPLIDHLMSFEHsYNIEIVPIK +>tr|A7RSL4|A7RSL4_NEMVE Predicted protein OS=Nematostella vectensis GN=v1g240412 PE=4 SV=1 +---RTVAMPVDGSQRSKDAFIWFCKHIIQEGDHVLLIHVWFVPSFNHdrltwpaikgpyedwmydkrvaedsvdemldwYISCNKNVSKSINKIPLNHGADKKTQCEEICKAAKEHSADMMVMSHKGDTTNADpGVLGLTTDYCVCNAGIPVCVL--- +>tr|A0A1X7LQG3|A0A1X7LQG3_9BACL Nucleotide-binding universal stress protein, UspA family OS=Paenibacillus sp. 11 GN=SAMN06295960_3978 PE=4 SV=1 +MMSNKILAVIDSTSLSQQAIEIAFQVAQKKRTALDIVFCEHHHRSifnfgftmiaslsysgyvpidqyaaedllviqaedQDKLNQLQRDAVLAGI-DASIFRVEGSPSPVIAELTEQYSYKLIVIGDRRVQRNRKRLFKHVRRKMEQSPRCPILIM--- +>tr|A0A090WAU6|A0A090WAU6_9FLAO UspA protein OS=Algibacter lectus GN=JCM19300_4468 PE=4 SV=1 +---DNIVFLVDYKEDEIIPLGHVIEKSQEFNSKLHVIHFdlAHVESISPLMETFKQSLDLAHLNNVEFISIDSiNLKKSLTEYCINNKIDMVCLINHKRNFYQRLFSFSLTEDLLNNFDIPIMAIYRD +>tr|A0A0S8BSJ3|A0A0S8BSJ3_9DELT Uncharacterized protein OS=Myxococcales bacterium SG8_38 GN=AMJ62_13770 PE=4 SV=1 +NPMSTVLTVTDLTAASYQLVGLAASIAGPSDGQVILVSTYGGGGTSrrseppfaeranpewwrqqlearlrqegQLLERQRQWCADRGVRCRAELYEDGRWPELVLQSAQRSPVDLILVGMHQMSSPYQ-ISPDEVRRLAEAAPCPVSMVR-- +>tr|V4QMM8|V4QMM8_9CAUL Universal stress protein UspA OS=Asticcacaulis sp. YBE204 GN=AEYBE204_04005 PE=4 SV=1 +QSWARISIPVSGSASEEVSVGIAASVAEGFGAQLNFLFAPPDPAElapwlgegfmgtvqvaamdglksaaEEAEAIARETFDGLDYDGKVFLPLKSPVWQCLAVETR--LSDLVVFGDESARGRG--LLSEAFQQVLMEERAGVFIARQ- +>tr|I4YHF5|I4YHF5_WALMC Uncharacterized protein OS=Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66) GN=WALSEDRAFT_62762 PE=4 SV=1 +---NKVLIGWKNSPDGNKALEHYLNKLAKPQDHVILLVVLPTTLFkssgfgtddkkmerkalrdlrehaQQLASEKIKLIEAKGA-TASLEIVHGERRYVIEWLALRRKVDLIILGRKKAHAPAKGLskvflghpIGSTVQHVLHKVSVPVLVVN-- +>tr|A0A1F8RBR7|A0A1F8RBR7_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_63_12 GN=A2W37_07805 PE=3 SV=1 +----SFLILTDGSASAQAALELGGQIARLAHARVTILGYGPTTDVlQRHLQEAKEKLGSGLAS-LEIRATLDLPHVAVAHEVERQVYDLAVLGFDASR---PPGGVALAENILRSGEHHLLLVSGT +>tr|A0A1Q6W979|A0A1Q6W979_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium 13_2_20CM_66_19 GN=AUH10_13910 PE=4 SV=1 +----SFTACAVSAALAEAL-SRQPLLAELaarMHTRIA--------------PRVEPHLG----V-PDAPSATDEPSVGA---------------TAIAG---GSDCSRRAEWLLRRGAREVLVLPEQ +>tr|H2BY19|H2BY19_9FLAO UspA domain-containing protein OS=Gillisia limnaea DSM 15749 GN=Gilli_2607 PE=3 SV=1 +KGLEKILISMDYDQVlDPSEIEPLRKIISGSQIFVEFLQLKKDDFDELLWKDQSEKLNKTfSDLNFTFQTITGVHFvAAVSSMVQIQKPDLLLLHAEKEKFLDGIFYASNISSVINKIKIPVLILHP- +>tr|K4IW68|K4IW68_PSYTT Universal stress protein, UspA family OS=Psychroflexus torquis (strain ATCC 700755 / ACAM 623) GN=P700755_003030 PE=3 SV=1 +SRIKEILFSMQNEEElSFKGMDIFKDILTMHKCRLNVLELDDTRQTQASEKVDNQSIHKLfLDYPYTYFHLNTIPGlIALNTTTQLLKIDLHAVSIEKETFLKRLLFGSDTSQLAYGTHIPLLFLHK- +>tr|Q26DH5|Q26DH5_FLABB Uncharacterized protein OS=Flavobacteria bacterium (strain BBFL7) GN=BBFL7_00769 PE=3 SV=1 +HKPTAVQYVLDYDDVfKVCGKELFLEIVTKFASTINVIRFNHGFQLEPINYrEERESFINFcMPSPVIYELHKDQEPlKIIKKSLSSRNYQLQAISVKSQSFLERMISESHISEIVNAATLPLLVLRD- +>tr|A0A162F9S6|A0A162F9S6_9FLAO Uncharacterized protein OS=Aquimarina sp. RZW4-3-2 GN=AWE51_10270 PE=3 SV=1 +KELKTVLYTIDYNDYfNQDGIEPLLDTVQKHKASLRILKIKEDETVTIADFDDKKHMKEFfKGINHTFHSIINVPTaLAIASFIQIMNVDMTAMFIQRETFLDRFFNGSETSKISYGTRVPLLIMHT- +>tr|A8UL12|A8UL12_9FLAO Universal stress protein OS=Flavobacteriales bacterium ALC-1 GN=FBALC1_06638 PE=3 SV=1 +KKPKAVLLPLDSFDSlSGKAFSDALKFIKVNNSTLHILRINPNGIEPDTQSKDFEHIDFHlKDITNTYNVVNNVPMhFAVSSYIQTNAIDLSILIEQKESIFERFFMGSSTTKIGNHLKAPLLVFHS- +>tr|A6ENG3|A6ENG3_9BACT Universal stress protein OS=unidentified eubacterium SCB49 GN=SCB49_03624 PE=3 SV=1 +EGVNSALFSTHNCEDfSLEGVSVFKEMLNIHQAELNVLDIKDEGVVVNS-KENDTYLKRLfTDYPYSYFLINSMPGlIAVNTATQLLKVDLHAVFIEKETFLKRLLFGSNVSQLAYKTLVPLLFLHR- +>tr|A0A098LNG8|A0A098LNG8_9FLAO Putative universal stress protein UspA OS=Jejuia pallidilutea GN=JCM19538_3049 PE=3 SV=1 +KKPNDVLLPLDVPDStSGMAFTAIVEFTEKFCKTLHILRIQPYAKNSKEEKRDRAHLDTLKQTNYVYHKINNVPIpYVVACYSQTHNIDLIAIIAKRESLFDRFFSGSPTTQITHKIKVPLLVSHS- +>tr|A0A0D5YQX0|A0A0D5YQX0_9FLAO Uncharacterized protein OS=Muricauda lutaonensis GN=VC82_568 PE=3 SV=1 +QMPKKMIFANDLKKPiGTTALKVLKDLIKCHDIALTMVYFDRGNAMNEEQKANRKLYEDNfVGLKYRFEEVPLKTsIsSAMKSMlSQRNDVDMVIFKKNRHSFFEKLLREPIIRKVAFSAKIPLLILPD- +>tr|A0A090X525|A0A090X525_9FLAO Putative universal stress protein UspA OS=Algibacter lectus GN=JCM19274_3350 PE=3 SV=1 +TPIKELLLSVGPRDViDGNQFTDLLEFMETYQLHLNVLRLMPNKENLDIVKQDRSSLS---ILNCKYNVVNMVPIdYAVLGYLQTNTVDFMALFVRHEGFLEHLFSKGNTKINISKLPKPILVLHN- +>tr|A0A0C5CD30|A0A0C5CD30_9ARCH Uncharacterized protein OS=Candidatus Nitrosopumilus piranensis GN=NPIRD3C_1892 PE=4 SV=1 +--PKHIMVPFRPSDVFFRAFDEAVTIAKQNNARITVVKVIDYRAglgidmmmaadilsrecdlhkFDGILTGLQKQAILSDVNlDVKIMDLHLSPAKAFVDFAYQNDVDMMVMGCIKKKGLTKHFRSDISDEIMDLSPpCNVVLV--- +>tr|V4M6B6|V4M6B6_EUTSA Uncharacterized protein OS=Eutrema salsugineum GN=EUTSA_v10022572mg PE=4 SV=1 +----FVAVAVKgiigdklGGAGSRRAVRWAVDNLLPKAHRFVMIHVIPTIstiptptgerlpveeveerlvemyvrDVKQEFETVFVPFLKMCKSapcts---------pNAAATARGFLKDGAASFH-------N---------VQSKTLSDPRqsIE--AG--- +>tr|A0A0Q6CQ94|A0A0Q6CQ94_9RHIZ Universal stress protein UspA OS=Methylobacterium sp. Leaf456 GN=ASG52_19455 PE=3 SV=1 +TGVRDVMVAltEEGRG-deVASSLGYGLTLARDAGAHLTVESASIRFVTTglvlgnfvdelvgaenrrmaslarSTAERIAQDAARAGVVCTTESPSLQYdrLVARLSALAR--LHDLTILDAEPLAVLPD---RDVIEGLLFESGRPLIVVPPG +>tr|A0A0Q6ZFL4|A0A0Q6ZFL4_9BRAD Universal stress protein UspA OS=Afipia sp. Root123D2 GN=ASC80_10380 PE=3 SV=1 +MSFKDVLV-aLTTYPErtPNSSIEDAVQVAVALSARVSAIACEVRVPAPasplgtallnipamvaaelrksaanakDVLAGFQDAAERQNVLQDTILEKCSTanEPDVLVDYAR--LRDLTVVPMTNT-DGNE---RWYAETLIFDSGRPVIALPPE +>tr|A0A0B1Q5D1|A0A0B1Q5D1_9RHIZ Uncharacterized protein OS=Aureimonas altamirensis GN=LA66_11565 PE=3 SV=1 +PAYKTVMLTllPEADARnaASPATAMAIAITSHFEGRLTIDFL--SPQPAwipyslvtdmpgqmlaeqtrkleaqahASMDLAAGAARQAGIHPETQLISLDFlaLVGRAALRAQ--LQDVVVVDAGGSSLRDE---REIVEALLFRSGRPVIRVPAA +>tr|A0A090N6E7|A0A090N6E7_AFIFE Universal stress protein family protein OS=Afipia felis GN=BN961_00093 PE=4 SV=1 +MIIQDAML-vLKAYPTptSEEVIASGIQLAGSLNCRISAFVPETLIQVPgsflgnslinisgmaalemdkskrnaaTLIKLFRDLAERNGIQHEVIKERELAgrIPALTAEYAR--LKDLILLPVSQN-DLVD---QWDTETIIFNSARPVLLLPER +>tr|A0A1B2EYL1|A0A1B2EYL1_9RHIZ Universal stress protein UspA OS=Microvirga ossetica GN=BB934_43465 PE=4 SV=1 +QNIRSILIGitEEGDA-eeRSSALTYGLALARQANAHVTVQAASLKLTVThafisafaeglvaaenrrldglarAVADSSQRAAAASGLACTAQAPQLAYpdLIRSFSSLAR--AHDLTVLDAEPIALALD---RGLIEAVLTDSGRPLIVVPQG +>tr|A0A1G7QRD9|A0A1G7QRD9_RHOCA Universal stress protein family protein OS=Rhodobacter capsulatus GN=SAMN04244550_03262 PE=4 SV=1 +MADRIAYI-pLNTCPEgpSDAATLATIGLAGTLDCRMHVATFAVNIPPVasplggflinvkgmacaiedrskaecdRLRALIEAAARDS-SDV-TFVHHQPVmgAaLDWATTESR--YFDLALTPWSPD-SAST---QDMAQSLVFGTGLPVVLVPPS +>tr|A0A1W9KAZ3|A0A1W9KAZ3_9PROT Uncharacterized protein OS=Proteobacteria bacterium ST_bin15 GN=BVN31_11645 PE=4 SV=1 +KSFKPITNLtcMVRVYDepSRAALDQALAIAQHSKAHLIVMIAAAKVSVPfspagawfasplvgdlnhqtmtkakEVAQEVRAKAMAAGISADIQIMFDHVenVAEKAIKAAR--ISDLVVVDQSRGRLDTT---GILFEAALFHTGRPVIVASPR +>tr|A0A1W1YSM9|A0A1W1YSM9_9RHIZ Nucleotide-binding universal stress protein, UspA family OS=Rhizobium sp. RU36D GN=SAMN05880593_1014 PE=4 SV=1 +SRTRVCYV-pVVTYPDvvPDDAVLAAIDFARALPCRLHVTAFSVDVPHIasplgdllidipdmirtvevrsahdcrRIQELVVGRVEGL-VEA-EFS-IQPQsgYpGFAAAREAR--YFDLSLLPWAKG-ATSV---QQVAQTVVFESGRPAIIVPPG +>tr|A0A1A9HYN2|A0A1A9HYN2_9BACT Uncharacterized protein OS=Niabella ginsenosidivorans GN=A8C56_04650 PE=3 SV=1 +--LGKIALASDLELLKEETLHQLQAFMKTTGADSLQVVTVNKEVNNPASEERVSAIKALlqPLSPTFHFIKAENVAAGLETFVAQNNISLLVFTHHERGFFSGLFHKSVGKKIAWNTTVPVLRLK-- +>tr|C0QUL6|C0QUL6_PERMH TrkA-N domain family protein OS=Persephonella marina (strain DSM 14350 / EX-H1) GN=PERMA_0592 PE=4 SV=1 +FPYSEITISLN-CPDPAFNLEIGIELSRLMKLPFEVLYITMPQElrgdeEEEKLRERHEIVSDFEQiykTNIKYKVLEGNPVKETLKFMSDEsKRKNLFITTYDKNEEISIFKPHVQYHITKSIKNSVLLLP-- +>tr|F0S364|F0S364_DESTD TrkA-N domain protein OS=Desulfurobacterium thermolithotrophum (strain DSM 11699 / BSA) GN=Dester_0635 PE=4 SV=1 +TPVNKILVPVSGSFSSFRALEVGIELSILLDAKLTALYVRLNN-SDEKVNYLKDKIVKFSSmykISIDFLVRTGNPVNEFAKISKNY---DLSIVGARKGRKTNWFNPYPPYHMIHRSNCSSILVC-- +>tr|A0A1F2WKD3|A0A1F2WKD3_9ACTN Uncharacterized protein OS=Actinobacteria bacterium RBG_13_55_18 GN=A2Y75_07730 PE=3 SV=1 +-RPAKMLVPLDGMPLPEYVSDTIFSIAEALHTDLDLLNIaaagkkpprvpgafpspayldHPYYDWPAWCSEFVKRILEEREPQVELTLfsKGGDPVRVTLQFALENSDDIVALHWRGLMSKKHA---ETVKGILRNAEKPVLLVRH- +>tr|U1PAD6|U1PAD6_9EURY Uncharacterized protein OS=Haloquadratum walsbyi J07HQW1 GN=J07HQW1_00535 PE=4 SV=1 +NSLDRLFVALGDGPEFDRILSFVADLLAAVDASVILFHTRE-----ETLTNATDQLVKRGVDsnRIYQQVSGGdNVRQRVVELED--KCDLLVIGEETPDPLNKtPVLETASTKMPLNTNDPAFIVRS- +>tr|A0A0S9LPP1|A0A0S9LPP1_9BURK Uncharacterized protein OS=Pseudorhodoferax sp. Leaf265 GN=ASF45_30210 PE=4 SV=1 +--HRSALVATGLDAEaAGPLLHAARWLCRPDG--VLACHVLDPTIQRhlhaadlplatvqswmetagrRAELALGQQLVQAGLPAGQALVLQGPALARLLHAQHSRAASLLVVGKPRRSRWADLLRPALARQLAARVASDVLWLPT- +>tr|A0A0S7YWS3|A0A0S7YWS3_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium SG8_13 GN=AMJ54_03420 PE=4 SV=1 +--MMKLLVYTDGKPAAAKALAFAAELKKRLVSELAVITVRSGTHATEepppvgidfpltdrnslpeglqALVDAIDVLEATGLmhrprsiriqdiarghlfvcrtvadERIAFYESFGHFIDSLNHEIERHQYSLLIISPQCLGKLQRLVKGDPVRKLALDLHTSVLVVRGG +>tr|A0A1V9FEJ0|A0A1V9FEJ0_9BACT Uncharacterized protein OS=Niastella populi GN=A4R26_25415 PE=4 SV=1 +SEFRKILFPVRPTLFSSKLFDVICELTRHNtqKCMLQLLGVVPGELkntisiLSKTVQEAKKQYNKEKFDIALSNGKSNDIAEYVLQRSKAINADLVVISQGLDLPSNPFFIGPFSQRIINHAKTPVL----- +>tr|A0A1F8P6A3|A0A1F8P6A3_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_48_7 GN=A2Z02_05505 PE=3 SV=1 +-MFDKILVVMGLLSRTWSAIPYVRHLARGFGSEIYFLGVSTESQPvwdqslLGYIEGISRSLEEENII-VKTDFIHGNPAVEVVKYSKKNNISLIVTTAGTTNEITCSILSNISRRMGMELSIPILTVPP- +>tr|D0LX45|D0LX45_HALO1 Amino acid permease-associated region OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_3585 PE=4 SV=1 +-----VLLPVANPGHARALVAVANALVPSNIGRVLLLTVLPRPQQdvaavgpdgataadaddilrrlkdaQEVVKNALTASYATGQAPEALITAAREPWREIERVASAHACECLLLGMSHGATTED---VVQVEGLINRVDCDVGILY-- +>tr|A0A1J5SVR0|A0A1J5SVR0_9EURY Uncharacterized protein OS=Marine Group III euryarchaeote CG-Bathy2 GN=BEU05_02935 PE=4 SV=1 +-MFSKLLLPLDPSKRLKAATDYSLTLARRLKLPLVAAYIANPAKTGAgselqdpekcffplGERELKRFAASVSDVEMEPLLRCGERNVVLAHMVAeEQAGDTLVLGPFR-SRLTRFFTGSEVERILEDVQCHAFVVRHE +>tr|A6DMJ0|A6DMJ0_9BACT UspA OS=Lentisphaera araneosa HTCC2155 GN=LNTAR_15962 PE=3 SV=1 +MHIDNIITGVFSEHHFSMAVRESQKLANVFKAKVRPVHVIETLGLNpfypreteesrlealnKFKADVDHLYNKHGANHIEEPVVqIGRIHNELVNVANDYDNPLIVVGRHT-EGVMHKFLTTEAERIIAHSNTPVWVHPH- +>tr|A0A090VCV5|A0A090VCV5_9FLAO UspA protein OS=Algibacter lectus GN=JCM19300_276 PE=4 SV=1 +TCISTIVYATDFEQQDIIPITKLIEIVRPFEALIEIVHIYHTDTTtaRERMEQFKNMLLEQvSYEDMTFKTIaSDKIKSGIISVINSENASMLAMLERKHEFRlDNPFRKDLVKEIKTRVDIPVI----- +>tr|A0A0R2F9H5|A0A0R2F9H5_9LACO Uncharacterized protein OS=Lactobacillus similis DSM 23365 = JCM 2765 GN=FD14_GL000446 PE=4 SV=1 +-----IVVALENSQNAHQIFNYALQLAKDYNKSVYGIYIINTVRELDctvdqrefwidsqeslakfNMEKRSQIAVRQGQ-HFISSITYGDPAVQIAKYVNLDNVCQLVMGRIGDRNLADDELGHKVASILKGIKKPVTLV--- +>tr|A0A0R2B7B0|A0A0R2B7B0_LACCL Uncharacterized protein OS=Lactobacillus collinoides DSM 20515 = JCM 1123 GN=FC82_GL002500 PE=4 SV=1 +-----VVVAMENTKNANRIFKYAIELAEERHKAVYGIYVIDTVQNLPydedqwetwietqealgtfNMQRHSEMAAEADI-RFIWSVMYGDPVRKIARFANLDNVCHLVMGAYGERHLAMDLLGHKVPEILSHVRENVTLV--- +>tr|Q9HIM9|Q9HIM9_THEAC Uncharacterized protein OS=Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) GN=Ta130 +-PYKTIYIPLSESVNTRGSVAFGLFLKKVTGAKVIFSDLrafdqNPTHKFSYVFDYMNEIIENFGGDiTVRKGGTSSDLKESILSEASNADADALVLGVRS-GPNGKIRVSSEIKDLMKTGEFDSILFK-- +>tr|A0A0D5ZHX2|A0A0D5ZHX2_9ARCH Uncharacterized protein OS=uncultured archaeon GN=IX51_10875 PE=4 SV=1 +-PYRSIFLPVSENVNTRTAVSFALNLKIATGAKLYLADLrgydtKIRHGFKLLFDHFEEMLERFGRDiVVIKGGFSETLKEELKSLSERLSPDATVLGVRS-DTSGKIRMSSNVKATIKENPGDTILIK-- +>tr|V4HFX5|V4HFX5_9EURY Amino acid permease-associated protein OS=Candidatus Halobonum tyrrellensis G22 GN=K933_06148 PE=4 SV=1 +----RVLVPVRRMQDAPMYARLAARMGELYdePTEVWFLNVTEIPEQtyseqvfdvaqarVDRLEDVLAGVdDLDATFVVEGHVSR-DIAFDVLKTTRETEADRILMGYPSQHYK-------LAHELEYGSPCDVLFV--- +>tr|A0A0H2KME4|A0A0H2KME4_9MICO Uncharacterized protein OS=Cellulosimicrobium funkei GN=FB00_13090 PE=3 SV=1 +--PHHVVLALSDEDRQDDLVRYAVEEARLAGCPLRVVHAVQTPALVhalyedwgagepwksvatSRISAMVTPVAARAGVHTFLYVAEGPVADKVLSQVS--TKDVLVVGGRHHHPATARALGSVADRLLRRSPGTVIVVHPS +>tr|A0A0Q2UM69|A0A0Q2UM69_9RHOB Uncharacterized protein OS=Loktanella sp. 5RATIMAR09 GN=AN191_16685 PE=4 SV=1 +-AYRHCAVAFDGSPEASEALRMALRVAPTARLTIVLTHDDSRSSArsdaeiriRSHVSSILAEFAERPAE-FELAPSDEAIVDAMKQVVEKLNVDLAAFGRTHRKGLAKLVQGGNTYMLLSHLTCDTLI---- +>tr|A0A1N7DRI1|A0A1N7DRI1_9EURY Universal stress protein family protein OS=Haloterrigena daqingensis GN=BB347_05555 PE=4 SV=1 +----RIFLPDFPDAtdDvTEQVLAFACSIKHRYGDEpVHLLRIQSTEARAgagdsdadsst--PGQFSGLEAAENTAINSDTTESEDVPATVAQTVDETETDLVVMGHEPSHASEGATFGRTADHVLAETSLPTYLVH-- +>tr|I4YDU6|I4YDU6_WALMC Uncharacterized protein OS=Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66) GN=WALSEDRAFT_60177 PE=4 SV=1 +---RSIMLAWTLDPAAQTALEYYITTLAMPHDLVHIVNVDTKGTGnlELELKERINQLEtqvAEGIQ-VISHTLSGETSSALVEFADKYSPDMVVLGRRNLGHWKRIASDegfSLSSHLATHIESPVVIVK-- +>tr|A0A136GVW8|A0A136GVW8_9GAMM Uncharacterized protein OS=Alcanivorax sp. Nap_24 GN=AXW13_09060 PE=3 SV=1 +MDGNGILVFLDRDLkAPQPALTKGLKLARAAGLPLTVMVNSDSAAMrravgldEERRQAAEKQIRKAwdkridalcGDHQVDKRIVsSRDSEQALRDTVRDCRPVLSVVHTSEEGRLRRHLFTPRDWLLIRHAPGAVLCVHSD +>tr|A0A1V5MFK3|A0A1V5MFK3_9BACT Universal stress protein family protein OS=bacterium ADurb.Bin425 GN=BWY75_00195 PE=4 SV=1 +----KYVVAFSSPKRSSKTIETAVSQARSTDAEIVLVRLIPDPGkvgivaqlissdrpldkARMQIDQCVEELKARGIK-ASGIVKMGEVAQGIIDTAKELGADMLYVGTTSVGGRQFFMMkkDPIVHYLVEHCPISLCLVRHD +>tr|A0A0P7XGL0|A0A0P7XGL0_9ALTE Universal stress protein family protein OS=Marinobacter sp. HL-58 GN=HLUCCO03_17045 PE=4 SV=1 +---NRIVVFLNdHDEANHRAALAAAEISRHDQQPVTIILGADGEPAGDQLDAIRQDLDVLGA-GTRLRVLADSNPLSIARMLREERASQLVISRESA-----LFHEPGADRLLAALSLPVTVTP-- +>tr|Q0A8H2|Q0A8H2_ALKEH UspA domain protein OS=Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1) GN=Mlg_1516 PE=3 SV=1 +----PITAVIVrADEQAEAALRVALSVVGNRARALNVLVLPPEGgpVTDARLGEIAEWLEDQGV-SAHLRVVYPPDENGLLRALLQEQTGAVVITRNAH-----ETQADreMVSRLLERVDLPLLLLR-- +>tr|A4BTM8|A4BTM8_9GAMM Uncharacterized protein OS=Nitrococcus mobilis Nb-231 GN=NB231_00325 PE=4 SV=1 +---RPILVLYEgP-ETGDRALDTAALMARDANQALTILLPPSAEtQVERLEQTARNWARRHKT-AVSFMRLPSADAPILVQALRQTGGQVLILSRASH-----AVQNPAHRSLLDEIVLPVVVVP-- +>tr|A0A110B593|A0A110B593_HALHR UspA domain protein OS=Halorhodospira halochloris GN=HH1059_1540 PE=3 SV=1 +---TQLRAALlieaDsTSHSGLETLRLAHAMLGEHETLATVVVEPEND-SELIDKQLRPWLLDHYP-RARLISTTDIDAEQIAGIVADDCIGKLILSRRSQ-----LIHYEAAELLVDRLRIPLLVLP-- +>tr|A0A0S8BGF3|A0A0S8BGF3_9PROT Uncharacterized protein OS=Acidithiobacillales bacterium SG8_45 GN=AMJ68_10675 PE=3 SV=1 +---DAVVVLFDGSDESVRGLELARSMAASHEDPLSVVLLTRDAdIEKLQQQALEYVGATADV-DIRALPVSQ--LDQLPAILNITKCGVFLVPRSIS-----QTIDLLDIERLAHLRCPVMLLS-- +>tr|A0A0K0XTD1|A0A0K0XTD1_9GAMM Uncharacterized protein OS=Wenzhouxiangella marina GN=WM2015_533 PE=4 SV=1 +---GPMVLVLDsE-AGVERLLQQALRQARASRRDLIVLADPDLD----GLDALNTALAEQGM-QLHL--ARIRGPLSLLKWLQDLGGAQLLLDRGSP-----LLARMLNEQWLINLDRPLLILG-- +>tr|A0A0W1RWW1|A0A0W1RWW1_9GAMM Uncharacterized protein OS=Halothiobacillus sp. XI15 GN=AUR63_07605 PE=4 SV=1 +---AAIVALIGePQTSG-TIIETARLLARASDRGVRALLLPGADpA---ELPVLSSAPPADCP-AMTVERLAGRGLEALRRALRKQPAAALVLDDQAA-----LAFGIPMADLIADLDTPIIRIP-- +>tr|F9UGX3|F9UGX3_9GAMM Putative uncharacterized protein OS=Thiocapsa marina 5811 GN=ThimaDRAFT_4176 PE=4 SV=1 +---PLVGVLYSGSEGATRALAIALELVVRHAANLVVILQPEISaDTATLRGRVLEQLATLHE-QTRLVSLEGADAAGLSATVGKLGIDLLILDETNP-----LLARASLWNSLESLGCPVVIGR-- +>tr|I0HYZ4|I0HYZ4_CALAS Uncharacterized protein OS=Caldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1) GN=CLDAP_01920 PE=4 SV= +----PFTVVHLGDAPSTHAVRLAAQLAKPRGASIHILALPQSRqQADEIAQEVAAS----GL-ECTVSTA--PSTEAMTALLTQIERGAVILPVSVA-------------PWLDLLSVTAIVTP-- +>tr|U7P8R8|U7P8R8_9GAMM Uncharacterized protein OS=Halomonas sp. PBN3 GN=Q671_17575 PE=4 SV=1 +---GPLRYFRGeAPALPWG-----------------------------ETPEEAVRRHPLFL---GREELAPMDAPALERFLARARRGALVITRARL-----ITLLEQDVDLLARIPVPVVVVP-- +>tr|A0A1F6TPK7|A0A1F6TPK7_9PROT Uncharacterized protein OS=Candidatus Muproteobacteria bacterium RIFCSPHIGHO2_01_FULL_65_16 GN=A2637_03690 PE=3 SV=1 +---SPVVALYDGSPASVQALELAARLLPDEEQRISVLVVADDPqQARRLEAEAAARLKKNGV-QARFRLLAEADGASLRRAIQSETPGTLVLAAGMT-----ALRDETIQELLEAGDCAVLLVR-- +>tr|A0A1E4I9K5|A0A1E4I9K5_9PROT Uncharacterized protein OS=Thiobacillus sp. SCN 63-1177 GN=ABS89_00460 PE=4 SV=1 +---GPVMVLFENVSASASSLAMGVMLARRNGAELVVLVSAASKdAYRAACAIARSALKDRGA-AGRCVWLPTLDEASLIQTAKNEMAGCLVLADRER-----FLRQAGFERMLDEIECPIVLTH-- +>tr|A0A1F4BA54|A0A1F4BA54_9PROT Uncharacterized protein OS=Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_65_24 GN=A3I01_15995 PE=4 SV=1 +---PRFVAVCTAAARPEELALSLNGLLRSSAEPVDIVLLCEDPvLAAQWERKARALLAETGG-PHKLRIAVAKDHAELLQLLSRRAGGSVQRFRERH-----Q----------------------- +>tr|A0A231MZZ0|A0A231MZZ0_9GAMM Uncharacterized protein OS=Zobellella denitrificans GN=CGX12_07370 PE=4 SV=1 +---EMVLAVWEEAARDAPVLARAEQLARQQQLPLWITVPAAGA------DELGPALEPRGL-KGAMLPITDWSLPGVM-AAASDRASLLVLHRDSP-----LLAGARMKNINAALLVA----P-- +>tr|F4L309|F4L309_HALH1 UspA domain-containing protein OS=Haliscomenobacter hydrossis (strain ATCC 27775 / DSM 1100 / LMG 10767 / O) GN=Halhy_2801 PE=3 +------LVALEMGKADESVLHFVHFLTQTLPIKaITFVHVLPKVDLFfndftqnmqnliknyghqdevlDQMRNKVSSfVDAENGPRLHFSIREGNPLEEVLQEARLSGADLLLVGQRSGTGN----HGILARNLVRKSVGNTLIIPE- +>tr|A0A0J1DBL1|A0A0J1DBL1_9BURK Uncharacterized protein OS=Massilia sp. WF1 GN=AB595_11200 PE=4 SV=1 +-MPKPVLVISESPHPVAHAAARAAMLAAALQCRrmEFLCAARGAGTLCKGMEEVEHAGAAaqlrFGV-HCSAQFDTGAFPAALMQ--RALDADPLLIAAAwqAHEWWPILHNFNLLRDVSRASLTPVLLVR-- +>tr|A0A0P7WFI7|A0A0P7WFI7_9BACT Universal stress protein family protein OS=Bacteroidetes bacterium HLUCCA01 GN=HLUCCA01_09575 PE=4 SV=1 +-SMEHITVPVDFSAQSANATALALDLAGGSYDKVTLQHIYSPMKEFfpympaekekkaardKAIKAAAGFIREYKLNpDVDIELtlfREDRMSDEIYNLCNQRKSDLIVVGYRARKNLLASLKDNLPERMSGYGfGIPLLIVKN- +>tr|A0A1R4B6J8|A0A1R4B6J8_9VIBR Universal stress protein family protein OS=Vibrio sp. CECT 9027 GN=VPAL9027_02534 PE=4 SV=1 +KAPSRCIVAFDGRSHNLAFIRKILLMPLLHSMPLDLVIVNANEEERHYFQDAEAYWVANGK-EVSVTELQGNVAQELANYQLSRPDSLLVISASPHSRFLRFWLGSHTKDILCAAEGPVLIISN- +>tr|A0A1W1BCG6|A0A1W1BCG6_9ZZZZ Uncharacterized protein OS=hydrothermal vent metagenome GN=MNB_SV-12-734 PE=4 SV=1 +REYKNILIPTDLSEKSKKSIEFIKNS---FDANLALVHGYESVTAtmsmydisyvnmveyqkenRDIALELFGAFQKEVGVEGELTDANFSLPHGVLEYIEDKKPDLVLVTSH--SSEESFFVGSMSSYLAKESPYDILI---- +>tr|A0A0S8CZ36|A0A0S8CZ36_9DELT Uncharacterized protein OS=Desulfobacterales bacterium SG8_35_2 GN=AMJ61_02320 PE=4 SV=1 +---MNVIAAINGQVTSEVAALYSLHFARIQGLPLILLHVANPDDSIAAVEKSMANIERAAAEydiVPERIILEGPPAETVKRYLSENKSEILFCSTRYRqrKKFFNLAFSEKLRSMSLPADLAEV----- +>tr|A0A1D2U0S4|A0A1D2U0S4_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium SCN 57-15 GN=ABS95_02065 PE=4 SV=1 +-GFRKIMVIIASEDTAAHCLDSAMMFFSTETSEIHFMSLAPRvAPELPHARPVRNGLATRKYPkPVEVFLHESvsiEPEQDIRRLAYSFEIDLIVMIAHPGPGLLSVFLKRADERILRAAPCPVVAVP-- +>tr|V2TQ14|V2TQ14_9GAMM Uncharacterized protein OS=Acinetobacter nectaris CIP 110549 GN=P256_00581 PE=3 SV=1 +--MKRVIACVDSSPCINAIAEAASWIAKRTQRELVLLQVLDYYPASyhlgeisgvigfesnamllkelaeleekqstlavdysnNLLKHLITTIKEKHGIDASVIQEKGDFLEQSLGVLR--EDDIVLIGKVGESAAEKnKVLGSNVENFVRGANCTVMTVSDH +>tr|A0A1H1KYR0|A0A1H1KYR0_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Gillisia sp. Hel1_33_143 GN=SAMN04487764_0160 PE=3 SV=1 +RLLNEIIIASDFQEDSKPTFDLLFKFALSIKLRVKLLYINVPYNFketPEIELSIQKFMEDKVVDRVETFIVdALNEKRGIAIYLAKEKPDLIATITHGRSVINNLFSPSITESLLSTFNYPVLSINMN +>tr|A0A0C2MJ77|A0A0C2MJ77_THEKT Uncharacterized protein OS=Thelohanellus kitauei GN=RF11_06520 PE=4 SV=1 +--MKNILLPIDFSCDVQQAVDFVINFVPKpyklvfvnayvceldgvfkefeyhiSDDQLHLILATVSTDFQDKLSKMEIIKKKYSILcSVETKILFAKgmgVREAVSHYLKEQKFDMMVIGSKNPSSFFGYIFKSFAADMLSESKVPTTIIH-- +>tr|A0A1R3X844|A0A1R3X844_9RHOB Nucleotide-binding universal stress protein, UspA family OS=Pontibaca methylaminivorans GN=SAMN05421849_2573 PE=4 SV=1 +----HVLIASEGRAVSDRVISRAADLLPGGKGRVTVLTVArlwgtsfglpnpglrpskrEMDEQKEIMTSALDRLEALGIEADGHIVTTRHPAKSIRRKLHKGDFDAIVMGADPRRPWfmRGFMWSQEPWRVKATMPVPVHLVCPD +>tr|A0A0F5HLT3|A0A0F5HLT3_9BACI Uncharacterized protein OS=Bacillaceae bacterium MTCC 8252 GN=QY95_03960 PE=4 SV=1 +-MYSSILVYADDAEHALEAVKHVQ--QPSHKLEeVTFLYIHPVSAHLpeslpdrirlveqlyahsDFFHEAKDYLDKLNIK-HKTVIRMGNPAQEISLITQFDRYDCLVVAKAA--------SEEAAAAITQKAKCPVVHVD-- +>tr|G6F1J7|G6F1J7_9PROT Uncharacterized protein OS=Commensalibacter intestini A911 GN=CIN_14930 PE=4 SV=1 +MENTKVVACIDQSTYSAYVTDYAAWITNSIHKPLELFHIGDCPPInaptdtaqktprRKLLNIYYERALEKGVDPslLQIHEEYGSFKEKVIRYED--NIDLLVMGRRGENTEKKhqDAIGKSIQKILRVLHKPVLTV--- +>tr|W7DSX7|W7DSX7_9PROT UspA OS=Commensalibacter sp. MX01 GN=COMX_08555 PE=4 SV=1 +MENTKIVACIDQSTYSAYVTDYAAWIANSIKQPLELLHIGDCPVPssqidvnkktprRVLLNTYYERALATGIDPslVEIHEEYGYFKDKIIEYEA--NIELLILGRRGEDTQ-KhqEIIGNSLTQIIRTLHKPILTI--- +>tr|A0A1G3GYI1|A0A1G3GYI1_9RHOO Uncharacterized protein OS=Rhodocyclales bacterium GWA2_65_19 GN=A2040_12110 PE=4 SV=1 +-KYRRILALVDANSDSAAVAQRAVQLSRFYGATLALAMVVESTPDLksnhapsfvtdemhqarmrDIRCKLEQMMSEIGCdCGCEIIIACGSEPEVVADLTCSWRPNLVLVDCRARHGLEQ---------NSKRADYDVLTVQYS +>tr|A0A0D2JBC4|A0A0D2JBC4_9DELT Uncharacterized protein OS=Dethiosulfatarculus sandiegensis GN=X474_03805 PE=4 SV=1 +---NKVLIPCDLSPFTLMQIRAALhAFHGRSDVDFSFVHVTDSTGTAIERWQKIIKNFEMDPSTSLKVIKPGkelNVAETLLGEVRKGDYGSLILGRRGgLARVRRRIFGSVSERLLDQLP--------- +>tr|A0A1W1WXQ5|A0A1W1WXQ5_9DELT Universal stress protein family protein OS=Desulfacinum hydrothermale DSM 13146 GN=SAMN02746041_00097 PE=4 SV=1 +--MERIVVTVSDeGMEALGALARGISLARRIGARLYVLSLERPGsraagassrlfsvgdEVAERMQMLIEGARADGV-SVDIHISEGSYEEALVRFCREYRVTLWIVGIPDKHRRDHHEALMRIHKIRARLGCAVEIVHP- +>tr|A0A0K8QYA0|A0A0K8QYA0_9BACT Uncharacterized protein OS=Bacteroidales bacterium 6E GN=BA6E_10964 PE=4 SV=1 +LTFKKVLIPVDMRKQNKDSLLWSAYFGRHLQSEVIAIGANDNSkearkSIAAHLLSFKNHLTKTGVAHKIYKGSKGSLAiqREAFETAQAFRADLMILLGSSYVTWLDQLIGLPEEKIIKKAIdFPVLIVNP- +>tr|A0A0L8V2U5|A0A0L8V2U5_9BACT Uncharacterized protein OS=Sunxiuqinia dokdonensis GN=NC99_43820 PE=4 SV=1 +LRYKNVLLPVDFRKVMKDTSLWASYFARFNKADVTIFPATEKNkenatMIRKNVKFIKHLLANLKLGFQIKNSSKGSFGlpFDALQRCHDKQHDLLIMPSSKNISLIDLIIGLPEAKIIKKANhLPVLCINP- +>tr|A0A0D8JD36|A0A0D8JD36_9BACT Uncharacterized protein OS=Draconibacterium sediminis GN=LH29_11445 PE=4 SV=1 +MDYNHLLQPIDLRKEISDSSLWCSYFGRFNAAQIVTISANDKTreakqNVLKNTELTRKLYEKFKIVHKRFRGSKSSLRnvFEALELALASDCNLLVILGSSNITPLDLLIGLPERKVIKGAGkLPVMVINP- +>tr|A0A1F3F8H3|A0A1F3F8H3_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWB2_41_8 GN=A2066_14230 PE=4 SV=1 +LQYKNVLVPVDYRKASKETSLWASYFGRFNHSLIQVIYARESDrdnenQLMRNVKFFQKFLSSLNVRLSLTEGKSSSWGicKETLENAQKLKGDVMIFSGSSTITLIDLMIGLPEKRIVQKAGnLPVMLINP- +>tr|A0A0Q7JT55|A0A0Q7JT55_9ACTN Uncharacterized protein OS=Angustibacter sp. Root456 GN=ASD06_14420 PE=3 SV=1 +---NRVLVTSVHGAAAGPAVQWAVQRAVSRHHPVHLLDRWSVHAMgpgltvgheyDAARQEALERhseameelrAVVAGRVPVTGELVEGRGVDVEYARSN--AGDLLVVEWDDTEH----------RPSLRYERCPVVMVPAP +>tr|B5IBQ1|B5IBQ1_ACIB4 Universal stress protein family OS=Aciduliprofundum boonei (strain DSM 19572 / T469) GN=ABOONEI_2194 PE=4 SV=1 +SEIKKVLLLTDGTAKSKRAENYAILLASSFGAGMEVLYIKDKKD-GEHVKKLDNVVWKASHWNIEVKKNIESMenKDALLSHFN--RNDIVVMGVGKKILFWRK-IGHIAMFVATHSPIPVIFVNS- +>tr|A0A124FMZ8|A0A124FMZ8_9CHLR Cationic amino acid transporter (Fragment) OS=Anaerolinea thermophila GN=XD73_0779 PE=4 SV=1 +NGLQNILVPIGNGPNARLALKLASDIAFQQNVNVTAIRILPQKASKETQEDELSQMQEIAESEIGSippymemrTILSNNVLDGIVGETEKKQYDLMIIGAAEEVYSPDYIFGKLNDVLVEEVSCSVLIVRR- +>tr|R7ZMP6|R7ZMP6_9BACT Uncharacterized protein OS=Lunatimonas lonarensis GN=ADIS_4455 PE=4 SV=1 +--PDKLIVFTDFSEPSQHAVQVSVELAKRLKRPLEVFHVLTAPPIPSmagvamrnellesakaeaelTLSSLVKRLEEAHKATVvkSSVIAKLGFEEAVERTAQASPNCLLIFGKKKRSALERMFVGSGLTSLLRRGEvgVPMLLVSPG +>tr|T2KKN5|T2KKN5_9FLAO Universal stress protein, UspA family OS=Formosa agariphila KMM 3901 GN=BN863_12740 PE=4 SV=1 +FKIQKIALVIGEDLiHDSKLLEVLLQVARRFKAKVDVLTVKQGVAEYgytivdEKNENAIMYYLENFYS-HHHFVDGPDIPTSIFKYAEEKNIDLISILPRNHTKGKTSSEGALTKALSEVSKTPLLVID-- +>tr|D1PEF3|D1PEF3_9BACT Transporter, CPA2 family OS=Prevotella copri DSM 18205 GN=PREVCOP_05601 PE=4 SV=1 +---EKILVPVKYPEYADNLMNLAFLVRNqKLNRGLICLNVVYEDKDmrynqeqgRRILEHCSQLAAATDVMTQTQVRIAANIANGIKHAFNEFQCSEIIIGMHMHPEVSPKFWGEFHQSLFNGLSRQIIMARI- +>tr|A0A083WNL0|A0A083WNL0_9FLAO Sodium:proton antiporter OS=Chryseobacterium antarcticum GN=HY04_04940 PE=4 SV=1 +---ENILLAVNHVKTVDPMTNLALLIKSkNTTENLFAVNIINEEKNdsskknaETLLDQVVEIGASADVKITPVTRYDTDIIEGINNVIKEYAITDLMIGIDEEKRFSPNFIYNLYSGYLNNNAANILVYHA- +>tr|A0A1G3P9C2|A0A1G3P9C2_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWF1_31_7 GN=A2015_00460 PE=4 SV=1 +---QRIMIAVSNNKTASELMNFAFLLRTkNSVEAVYPILVVDNSDDidlqiakgEKMLAPIVVQAISADIPVTPVTRADGNPSVGIIRAVSDLRISDIIMGWSDKAGFYSSILGGVTERVVKQIRQSVFITKL- +>tr|U5CA60|U5CA60_9PORP Uncharacterized protein OS=Coprobacter fastidiosus NSB1 GN=NSB1T_01535 PE=4 SV=1 +----KLLISINESPHMESFIRRSKNLSYTLGVPLYAVYFDSTGQLtnkeQEQLNKNISMAYRLGV--FVIRSTGENWVSSMLDVIRIEKITHLIFERLPNeKYIKRIFRRSELDRLISKCKnLDIYILSNE +>tr|M6Z007|M6Z007_9LEPT Osmosensitive K+ channel His kinase sensor domain protein OS=Leptospira santarosai str. 200702252 GN=LEP1GSC120_1133 PE=4 SV=1 +----KILAVINDGITSYSLLRYAKRLAYERNGELFAIYNQTRENLtkesLGQLEKNLNFARELGC--EILYAADKNPADSILRICEQKSITRVVMEKPSASRWNrWTSPAYKLAAVP---SrFELCLVPYD +>tr|A0A0D2VAI4|A0A0D2VAI4_GOSRA Uncharacterized protein OS=Gossypium raimondii GN=B456_013G072800 PE=4 SV=1 +---RRIAITVDLSDESAYAVRWSVQNYLRPGdavillhihptsvlygadlgSVKQKLKNEFDL-MTTKVNTLAQPLVDAQIPFKIHIVKDHDLKERLCLEVERLGLSAVIMGSRGFGAARRTskgRLGSVSDYCVHHCIEETkkKKITGE +>tr|A0A218Y2P6|A0A218Y2P6_PUNGR Uncharacterized protein OS=Punica granatum GN=CDL15_Pgr000272 PE=4 SV=1 +---RKIGIAVDLSDESAYAVRWAVQNYLRSGdavillhvrptsvlygadwgamdlsmregddeVSQQKLEDDFDTFTSTKANDLAQPLVDAHIPFKIHIVKDHDMKERLCLEVERLGLGAVIMGSRGFGASRKTakgRLGSVSDYCVHHCVCPVivVRYPYE +>tr|A0A0U2XLX3|A0A0U2XLX3_9BURK Uncharacterized protein OS=Pandoraea norimbergensis GN=AT302_16845 PE=4 SV=1 +PNVERILAAVDGSANGRFAAWIAGLTAGVRGTLTTVLAPAPDDAEEGtpdrsekkradaddtaneegagrhaydialsaamlaiprapgtpgvddkakdrkdaakEEKHPDdtakVLRREAErlvlrertgkapqktpelphgpvdndagdangaataasvdddrqrdadpapkhepvgeahddkrvsnatedgefvASDPsdaareqeAKQADTSHEATRISDEIGK-GYGFVIAGFDAPGEESD--------SDVPPLPLPTGVlpLTKA +>tr|V7FJM2|V7FJM2_9RHIZ Potassium transporter OS=Mesorhizobium sp. LSHC420B00 GN=X759_17930 PE=3 SV=1 +SRLERLLVLVDDSRIGKFTAHLAGLVGGGSGMPTTLLRLPTTLLQPKdgridrpsdskGQERALQEIKKGAkksaqavkriedtlvgKFHLTARTELEATGETIAEEARK-GYGLLLVGLDNVLT--------------ADGAFAPALndIAAG +>tr|B4D484|B4D484_9BACT Sodium/hydrogen exchanger OS=Chthoniobacter flavus Ellin428 GN=CfE428DRAFT_3722 PE=3 SV=1 +PRLQRALVAVDRSAAGEFAAMLAGWLIGSRHLSATIMETGEADSRPEeafspskrllesasg----------AAHkievreekemkehpperdpldaaahaahtqqlrIQDLitlmpakkRAHGGEDPMADSILTEAKN-SYELIYLAVGGYLLD-------------GSSKFPASVekIVRD +>tr|A0A192M7M8|A0A192M7M8_9RHIZ Na+/H+ antiporter protein OS=Rhizobium sp. N113 GN=AMJ96_PD00096 PE=4 SV=1 +SKFERILLAVDNSASSGLATRIAAHFTALRKMPITVLNIDGKPQGPEaqsggnkdeagrTIDNTAmaiaEQVRESAqrtvgrvgsqeaaidgDLHVTTSGTSGDLEALLAESAEK-GHDMLFVGVEPTAA--------------PEGGLDQKIsrMSKS +>tr|H2CKE1|H2CKE1_9LEPT Transporter, CPA2 family OS=Leptonema illini DSM 21528 GN=Lepil_3589 PE=3 SV=1 +HSLNRVLLPVRIDPEGassrIIEAGILNLLGSTNRLQIELLNIPYKAAEKQqgl-------------dylkkirpLFH-vekmILRAvPGKEPAAIILDEARA-GCDLLMLGAPRDN-DLRGGGLfnPIIDTIVRQSPCPTLVVSKG +>tr|A0A0F6W0E4|A0A0F6W0E4_9DELT Na(+)/H(+) antiporter OS=Sandaracinus amylolyticus GN=DB32_001372 PE=4 SV=1 +LRLRRAVLVPSDGTASl-LAARLLGLIGVRTPLEVSIVDRTGGESAAVryaeslak-----------------HPKGeLRTAQDEKTARRVEE-DADLLAMGAPPPR-KGISRFLfgPRIDRKVLEAKQPVLVVDAA +>tr|A0A1N7EAW0|A0A1N7EAW0_9EURY Transporter, CPA2 family OS=Haladaptatus litoreus GN=SAMN05421858_4179 PE=4 SV=1 +GSVSRVLLPTRCSVHAq-LAAQLLGHIGRNRDIEVTNMYVVGASESETdslagrirrrlskytsskytsdapsprsng-------------gpsatnspdpttnavaedcldnttrQLSLsqemvhNRVRpRRGTVGETVTRELHR-GYDFLALGMGIADGESGRNPGdengtgrktrdgngrplfeLGIEDVLRATSTPVMAVNAN +>tr|G8TB22|G8TB22_NIAKG UspA domain-containing protein OS=Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10) GN=Niako_5130 PE=4 SV=1 +SHFKKIVLPLTDEVPVRR-IKFATLLARTFQSTVYLVSLRKDGNAaEQVVNKTLEVIQSLSTIPVQCFLLEGkNLAKSTLDFSKRINADLIMANPLKEFHMPGWWNRITRKLLSYGSKIPVITVDKN +>tr|A0A1F3PPT3|A0A1F3PPT3_9BACT Uncharacterized protein OS=Bacteroidetes bacterium RIFOXYA12_FULL_38_20 GN=A2281_13820 PE=4 SV=1 +NKLQHILVYTDFTEVGDNAVKHAAEMARIFNKNLTILHVIDDNTNtlfkknteekvEQKLEEIAASVRQGCPFEVKTMYEEGCACKIINGTSETIDAVMVVLGVHEKNMI-QYITPKYALKKIAKSRIPYLLIN-- +>tr|A0A0L0D8W0|A0A0L0D8W0_THETB Uncharacterized protein OS=Thecamonas trahens ATCC 50062 GN=AMSG_00598 PE=4 SV=1 +-----IAMAFDGSPVSLRALRMAHGYARKMGSSLHVCSVLTATRGESALTELmasalevepnLDALQAIGV-DVAFLDREGSVAETIMAHIEPLAPLATVLCTAT-IFHSEHLLGSVSRRMVRRGKFNILLVKPT +>tr|E6PH52|E6PH52_9ZZZZ Uncharacterized protein OS=mine drainage metagenome GN=CARN1_1188 PE=4 SV=1 +RMVGSIIVVFAENIASQHMMALAAKLAKGERSELLAIYVVSVPYSLppdaemtdeerralDALGAAQAIAAKADINLRTETVKARSTKQAVLDIAKRERANLIVLGSFREGKYTAAPLSRTIEEIAAEAKCDVLI---- +>tr|A4CPK3|A4CPK3_ROBBH Uncharacterized protein OS=Robiginitalea biformata (strain ATCC BAA-864 / HTCC2501 / KCTC 12146) GN=RB2501_02830 PE=4 SV=1 +-------------------MEYALLNYPGEPIHVVLVHGFRSPDSkwgliqfstrsevrklrSEDFENALNRICRThgkSIGSVQTLLFTGRNTHAFKNAIEPLEITDAVVPENGT----------------------------- +>tr|A0A1M5QKL6|A0A1M5QKL6_9BACT Uncharacterized protein OS=Chryseolinea serpens GN=SAMN04488109_2859 PE=4 SV=1 +-MRKTILIPTDFTITPLLLLKHVAATSA-VELDVIFLYCTSLPDSitdllfyspkkiieaavTTAFSEGCAVIQNKypeKIQSIRFELFHARSVDAFQIMAEMNGIDEAILAHTPA----------------------------- +>tr|A0A1M7B975|A0A1M7B975_9FLAO Uncharacterized protein OS=Chishuiella changwenlii GN=SAMN05443634_11090 PE=4 SV=1 +-GNKRVFIPTDFSIQSLSVINQLVKESSNTVFDIVLIHGYQPSNTitdllffsknkmieklqKSAFVKAYEVIKNAnqsTISSIKLDIIPFKRNLYIKNFFENSNIDSFIIPSTQQ----------------------------- +>tr|A0A1Q3N001|A0A1Q3N001_9BACT Uncharacterized protein OS=Bacteroidetes bacterium 47-18 GN=BGO09_12360 PE=4 SV=1 +-MAQTILIPTDFSIDSIQVLREYLDRNAaQAGLQIVFAAGYDTGSSitsllfhsrsrilqkmnLESFNEALHIIENKysnLIRGIRIEFFSGWNQSSFRNFLAGNRIDHIVYTSDMR----------------------------- +>tr|C7P3H1|C7P3H1_HALMD Uncharacterized protein OS=Halomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541) GN=Hmuk_1528 PE=4 +-QWERALVPVRRAsDVAHSMIDFAIRLTGATG-EVAVCTCIGPSANRRRAESMLSNLANPFAAPIETRVARQEIVPFLRGTAP--AYDLVLIGASRDRSAASRFVAPPTFESIAEMDTDVAIVDRG +>tr|A0A0E9LZQ8|A0A0E9LZQ8_9BACT UspA protein OS=Geofilum rubicundum JCM 15548 GN=JCM15548_13104 PE=3 SV=1 +MATQKILVSTELDELSAKITEFAVGLSAQLGAsELILLNVIIPARVHTfsttgdistydthnvnlfntelmkkhqlLVNEEAMKYSSAQI-NVKPVVRFNESKTNLNSLIESFKASLVVIGSRDEDSLLSQIFGSHSDEIVKKTDYPAIVLKED +>tr|R5ENE1|R5ENE1_9GAMM Universal stress family protein OS=Succinatimonas sp. CAG:777 GN=BN779_01157 PE=4 SV=1 +---QSVILAIDFTDaaqvgkLDDYLFDAASSFAKSFDGTVHIANCVTPKNPglmggnlsqskivssgglesrvGVHFKLAEEFALKHKVPLENVHVVEGRIDEEIPRLCEKFNARMVCMGTTPRSTFLGSINSSAGEIVLEQIKGDIFIVNS- +>tr|A0A1Y1IE37|A0A1Y1IE37_KLEFL Uncharacterized protein OS=Klebsormidium flaccidum GN=KFL_004110010 PE=4 SV=1 +---KLVMLAVDSSLESRGAVMWAARSLINAGDEVVIFHAIKTLKEIptamgmvpfsganpemqrahmlvteenakKMAATHAAYCQTQKI-EAKTEVIWGQRRQAILDRVVQLGVTHLVMGTgKGSRRLSFLRKESLTATVSREARCQVFLV--- +>tr|A0A150PR90|A0A150PR90_SORCE Universal stress family protein OS=Sorangium cellulosum GN=BE08_45690 PE=4 SV=1 +-RNRSVLVALHGERVHLGAVDLGRIIAGALRAPLHGLFVCSEPIDPSDVPAHLGVDPEALH-GVVLHVDASDDlPGALAEATERGDAAFVVVASePEELTDNRLGVGRLAARALEAAACGVVVIHP- +>tr|A0A150QCH1|A0A150QCH1_SORCE Universal stress family protein OS=Sorangium cellulosum GN=BE15_25600 PE=4 SV=1 +-RNRNVLVALHGRRVHLGAVELGRLIAGALRAPLHGLVVSSEPIEPSDVPAHLGVDPEALR-GVVLHVHASDDlPGALASATERREAAFVVVASePEELTDNPLGVGCLAARALEAAACGVVVIGP- +>tr|B5WNY7|B5WNY7_9BURK UspA domain protein OS=Burkholderia sp. H160 GN=BH160DRAFT_4790 PE=3 SV=1 +NTFRRVMIASAGGAGLPSGTRVAQQFAA-ADARFRLVNIVCNPAAlyptlmlsypdwceahramlhgaQLALREAVTALHGVVAatdaEIVDLTVLHHGAAEALAHPAAQWNADLVVVAAHARE--HRWDSRIDPEELVASIGRPVLYLPPS +>tr|A0LHM7|A0LHM7_SYNFM Uncharacterized protein OS=Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) GN=Sfum_1237 PE=4 SV=1 +-DPERAAICVLNEDASLRIADHAAFMLADTTVEITLLHASRTVPrmisahpagvmgeelgswlktpagqvIEPFLAESRQILRTAGIDESRVRVtlipDKGNTAMEILSHCREQGIGIVALGHSEPAGTWGFFKNSVTRKVLSEFK--------- +>tr|A0A0S8ITX3|A0A0S8ITX3_9BACT Uncharacterized protein OS=candidate division Zixibacteria bacterium SM23_73_3 GN=AMJ91_02360 PE=4 SV=1 +RKEYKILVPVANPGTLGMLMMTACAIAKKFDGEVIGLSVVEVPHRtplrkgladfsqqRLLLSRAENIARQERVKFDKLIKLSHRLSYGILETAEEEDCNFIIMGRSKPEKTLEKILTTVMDIVLKEAPCNVAIVC-- +>tr|A9B6K9|A9B6K9_HERA2 ABC transporter related OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_0260 PE=3 SV=1 +KPCNKALICVSDGEPSKEDVAFAGRLLGSVGASATLVSVASHSNDIERLERFLQTsaasLRRHEVV-TETKVLVGNVAQTINAEIKRGGYDLVIVGAPLGAYSSNYDLGSVVGPLLSQISVPVLIIRSS +>tr|A0A223NY28|A0A223NY28_9SPHI Nucleotide-binding universal stress protein, UspA family OS=Mucilaginibacter sp. BJC16-A31 GN=MuYL_2875 PE=4 SV=1 +MLMKNILFLNELKSQDDSTAKNALRLAYALRCDLILLCPFNEEGILknisddhgvcesfdlsrkelllnierqlKMLQPILDSSEGFRPQ-LQYLIKEGSIENSIAQIIKNDAVYMILIGTHHCMDFSNFLFGKYVNQIADQAKCPVLLIPSN +>tr|A0A124F8K7|A0A124F8K7_9DELT Uncharacterized protein OS=Desulfonauticus sp. 38_4375 GN=XD41_2003 PE=3 SV=1 +KRIKRVLLLLDGSKLSWQILRFGQWLARIFSAEVKPVYIEEPSLLPQkiyarevrffsfqvqrenffwqkevrfKEERVRKFLGQGEVSDLHLAKVQGNGEEVLLNQVT--SGDLVILGKRGWSKRGFFCVGSTATQLLKKGRASVLLL--- +>tr|A0A1C2GQZ8|A0A1C2GQZ8_9SPHI Uncharacterized protein OS=Mucilaginibacter sp. PPCGB 2223 GN=BEL04_06210 PE=4 SV=1 +-GFKNLVFATDLSDGSVSALNSLCDMAKYFDSEIIITHISDRGLLAHNNTVLEKYFDRVDAEitypkKRFKIIKDTNILRGLKTIPQKLNADILAMVHRKRNYLQRLFNKSVSHAMVNYPVGPMIIFPA- +>tr|M0CWH1|M0CWH1_9EURY Cationic amino acid transporter OS=Halosimplex carlsbadense 2-9-1 GN=C475_06615 PE=4 SV=1 +----RVLYPVFGSESEAV-IHIGASVAQGTDAELVVGALDDvagEPSFDASRDLAKTVFRaqtdcALDVH-VQAVPLAGsSVLEGIVSGADTYDAGVVVLGD----EVTEPRESKLAGRIA----GDTVVVN-- +>tr|D4GQ75|D4GQ75_HALVD Cationic amino acid transporter, putative OS=Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2 +----QILVPLLTREVPVLTdqLKVATTLARVTGASLTVIN-----PFPDPEQAP-NVYRheatdcENASlldwvfeqtdeslPQVESDFLYAwDVVRGVLQAVRRRDVDTLLVPSSSGT---SRLRKRMTEQLATHADADVIVVN-- +>tr|E7QSK7|E7QSK7_9EURY Cationic amino acid transporter, putative OS=Haladaptatus paucihalophilus DX253 GN=ZOD2009_08913 PE=4 SV=1 +----NVVVLSDGG---DAErtVSFAATLADARGGELILVNAAVrssGTPLN----LAGDVLNerqaaarrTLRTtvdsafdvr--TRAAARVGrNYLTIARTASEEFSAGVVVVDESESM-TSTAFGRSVSTRVGGHVDCDVISVG-- +>tr|A0A0B5H133|A0A0B5H133_9EURY Uncharacterized protein OS=Haloarcula sp. CBA1115 GN=SG26_17500 PE=4 SV=1 +----RILYPIFGTHDDF-TFETALNIADGVGGELLVLDLFTgdaTRSSETTS-----VGR---KllqarldetHTADAHliVEETdTPLKTAINVAQQRHVQLAVLDEHTPELFGEGLRGDAADRMRKKASCDVVSVT-- +>tr|M0L3Z0|M0L3Z0_HALJP Uncharacterized protein OS=Haloarcula japonica DSM 6131 GN=C444_17252 PE=4 SV=1 +----RILYPIFSTHDNF-TFETAMNIAEGVEGELLVLDLLDdnsIHSAETTS-----IGR---KllqahidedHTVDAHliVEETdSPLSTAITVAQQRNIQLVVFDEHTPELLGEGIRGDAADQMRKKASCDVVSVT-- +>tr|U1Q481|U1Q481_9EURY Universal stress protein UspA related nucleotide-binding protein OS=Halonotius sp. J07HN6 GN=J07HN6_02857 PE=4 SV=1 +----RVRA-----------AAVANAIATDRDAELLLTESVDvgeST--EAMLPLP-----ssHRDSHSIGATLLETsNTIQPIVNE---QDPSVLVMERASGTTFFSDLRASMAERLAA--ETDVLTVD-- +>tr|A0A0U5H0S3|A0A0U5H0S3_9EURY UspA domain protein OS=Halobacterium hubeiense GN=HHUB_2109 PE=4 SV=1 +----RVLVPFCEAANRA-EtSRLGASITFGSDGELYILHATDgeaSADAD--------ELRheaELELelreefsvPVTQFETEYSsGVLDSFVDS---HSITATVV-DREERGFFSRGRDEQTVA--S--GCHNVVGT-- +>tr|A0A100VYP0|A0A100VYP0_9MYCO Universal stress protein UspA-like protein OS=Mycobacterium brisbanense GN=RMCB_2516 PE=4 SV=1 +---KWIVVVLDETDSALDALRAAMREAGLRDAPVLVLESWshgrhtdtantARHPVRTVLEEYLTGPGASVDVQLSTLPMPTHLLHLLHQCV---SIDQLLVVAADHHALVEELTSPRAREILRGTDCSLLFTR-- +>tr|A0A0U1A6B5|A0A0U1A6B5_9MYCO UspA domain-containing protein OS=Mycobacterium abscessus GN=ERS075544_02233 PE=4 SV=1 +---GVVLIEFEDAPDSHAVLQHGLDAAAERDAVAQVVGHLpssptgsqtkddSAAILNARLERHLEPWRrKYPDTHVEVHLLHGGLPKYLSQQG---DSIQMAVIGRGRSGGLNELLRQQQATSNPGTGCTLMICG-- +>tr|A0A1A2S973|A0A1A2S973_9MYCO Uncharacterized protein OS=Mycobacterium sp. E2479 GN=A5686_21410 PE=4 SV=1 +---PGIVVEVDNSPDSAKLLGIAMEEARMRNATVHAIVCRrsvshdvavegkHDLRAVADLDRRLAGCRrRYPHVQVEAAAAHNTLLEFLGCNR---GSVQLAIVGSQNREHLQELVGPVGSAVLQAAGCSLLVVN-- +>tr|A0A0D3L9M9|A0A0D3L9M9_9BACT Uncharacterized protein OS=Flammeovirgaceae bacterium 311 GN=D770_00590 PE=4 SV=1 +NEIKKILIPIDFSAVSLNAIRHANSILQEHPAEVVLVYVNTPErklreqEILNSFRKFEENHLTGIFFSYSFDVRHGKLLNVLANVTLCHTPDYTIMGLRER----------------------------- +>tr|A0A162NFU4|A0A162NFU4_9BACT Uncharacterized protein OS=Flavihumibacter sp. CACIAM 22H1 GN=A1D16_06550 PE=3 SV=1 +--PQHLVLATDYQLADKKALPLLTAIASVFGADITVTRIISGHITreetakeqARFSEYSNLLQKDFAASSLSFQLITSsSIIDTLEHLEEEIPYDLLTMVRLKKTFLQRFFTESFTRNMAYLTRHPFLVMADD +>tr|A0A167WBT7|A0A167WBT7_9FLAO Uncharacterized protein OS=Flavobacterium fryxellicola GN=FBFR_11765 PE=3 SV=1 +--PKKITYASNYHKKDKKVLSYLLEINKLFNATISILHVDKGIMAftadEDFDKYKNTIENHFKDFEFSFKHITGeNVAKIILEETVADKTDLIvINPFKRKGFWNRIFYASITKKTAYLITKPLLSIPVQ +>tr|A0A0S1SEC4|A0A0S1SEC4_9FLAO Uncharacterized protein OS=Sediminicola sp. YIK13 GN=SB49_10610 PE=3 SV=1 +--LGHMVYSTDLQHVNEEI-ASVIPFAKLMDSWIHVLHINRGKEGfeGDLEEEEERLRKEFSYQKIKFREFKSsSIIEGINKFISVVEADMVVMFTHHTNFLEKVFQKSVTQNTAFQTRIPLLTFQKE +>tr|A0A1E7IR31|A0A1E7IR31_9DELT Uncharacterized protein OS=Desulfuromonadales bacterium C00003107 GN=BA869_04910 PE=4 SV=1 +-PFKKILVPIRSKDTIKKAFKEALLISSVAMGEITVVLTGETD-----GQEMEFMAREMGV-PLKIFQEKDEQrgvirkylrnpsciiLDTVKEHFY--YPDCIMVDPEELGIIDRLLGRGIILRLIREASLPVLVART- +>tr|A0A1F2P7P5|A0A1F2P7P5_9EURY TrkA-N domain containing protein OS=Candidatus Syntrophoarchaeum caldarius GN=SCAL_001665 PE=4 SV=1 +-PFDRLLVPHIAKTTAEKAFKEALLIASASRKKakIEVVSYDRSE-----QKMMEKKAKKWDV-P-FEFLlDEGELIDMLKHNIH--NTDCIIVDDEKITILDRIFPRNIILNLMRSVTSPVLVARS- +>tr|A0A1E5T128|A0A1E5T128_9BACT Uncharacterized protein OS=Fabibacter misakiensis GN=BFP71_16480 PE=3 SV=1 +KKFSKWMVGIDVTKNEVNLLRNVSELANQFtPDAIHIVHISKeldipkevlvdiPDLMMPDIKQAQASLEEmvakyfHPEQPVEIHVLSGNQLTELLRFENTHKIDLAILGRRNMNR-----VGVLSKKMVRKSACNVMLMPD- +>tr|A0A1R1YNL7|A0A1R1YNL7_9FUNG Uncharacterized protein OS=Smittium culicis GN=AYI69_g2058 PE=4 SV=1 +---RVVMVCVSGSKTsSEQVVDKSVKMVLNKNSDLVILLHVRKSNEncgytgqdefipgqadmnntfkaesYEILTNYGNKLKNLGYVIRAISVAGDDPGSEIAKKVSELSIDLLVVGKPEKSGISYFLSGNSCEKLFKQCDCTITLIKID +>tr|A0A0M3C3C6|A0A0M3C3C6_9SPHI Uncharacterized protein OS=Sphingobacterium sp. IITKGP-BTPF85 GN=L950_0227890 PE=4 SV=1 +--YKKVLLAVDLSHLHERLpVKMIFQMQELLSLEWHVVNVSIQGqHSAAQLIEEQSFLHSSldSLEPTYSYLEGEDIVEKINTYVEDHHIDLLVTAPRKLGFLATLFRKVLLKVSCSHQSTNIDV---- +>tr|A0A1V8RPF5|A0A1V8RPF5_9RHIZ Uncharacterized protein OS=Pseudaminobacter manganicus GN=BFN67_20225 PE=4 SV=1 +--PRQVLVASEGRRISEDVIQLAARIARGHDGRVRVLSVARLWGTsfglpnpglkpsrremaeqEDNVAQAIERLEALDVIADGHIVVTRHPAKSILREAGRLNCAAIVMGADPRRNpvVGSMMWSQEPHRVRRSAPIPVHLVGAS +>tr|I4VHZ4|I4VHZ4_9GAMM Universal stress protein UspA OS=Rhodanobacter sp. 115 GN=UU5_20535 PE=4 SV=1 +--MLDIIVKVDHAPSHPAWLDGVLALARRQQAFLTGLQVTVACLDtsdtiarsagdnddrAHGRRWWLELCRKADV-NGEWEVIHTAIPEVFAKRSC--LADFGICELRIGAADAPAGLHEVTH-TLFAHAVPMLLVPDI +>tr|M5D5K1|M5D5K1_STEMA Uncharacterized protein OS=Stenotrophomonas maltophilia SKK35 GN=SMSKK35_3908 PE=3 SV=1 +--LRDIAVLFDAGDTGHRVLNIAARLAQVQQAHLIAVSTAQHPSDiasgfargagiaaaldhearadaACTAQLMQNLRAAaepLRI-STELRIVSDyLGGADLSLHSL--YCDLIVAGYPQT-PGAPSGWHPLG--TLRQTGVPMLLVPPH +>tr|I4VHZ3|I4VHZ3_9GAMM Universal stress protein UspA-like nucleotide-binding protein OS=Rhodanobacter sp. 115 GN=UU5_20530 PE=3 SV=1 +--MLDVLVNVDEARDDAAIIRLGMDIGRRHRGFVTGLRIVDAYPLaiaipgalvvldaeereaKEQRAWWDGLCRRHKV-AGAWEVIRGIRLPILARRSC--LADLTIDRLPSAGNGMLVSMDNVTR-TLLAGTSPMLLVPSV +>tr|A0A101JB32|A0A101JB32_9ACTN Uncharacterized protein OS=Actinoplanes awajinensis subsp. mycoplanecinus GN=ADL15_45800 PE=4 SV=1 +-RGTVVAAAIDDDAHADEVLAHADRRARERGATLRAVHVWTGRGAVvgglrvrphglsyadlLLSTALYDGLDPGDAAAAEREILHDrDPARALRRLSR--ELSLLVVAAASEQVTPARPFGSTVGGLIGRTTCPLIVVSTG +>tr|V4J6T1|V4J6T1_9DELT Uncharacterized protein OS=uncultured Desulfofustis sp. PB-SRB1 GN=N839_04585 PE=4 SV=1 +-QLSRLLLPVDSLAAFERTLPLAEVLIRAMAVerkKVALLHVVSGSYLRDymegisvdrgdlpdteqmkqlrrrheenvvkpLMRQAGVLLHKTSGIeQAATIIEHGDPIKVIGEVCREGSFSTVVMSRQNEAERGGKLTGSVTAGLLHR----------- +>tr|A0A1M5WS29|A0A1M5WS29_9DELT Nucleotide-binding universal stress protein, UspA family OS=Desulfofustis glycolicus DSM 9705 GN=SAMN02745124_02506 PE=3 SV=1 +-PLSRLLLPVGTMETFERAAPLAGLLIRTMEIgadRVDLVHVVAGSFLGKrfksvdltagetvsteelqrlradylaetaepLLATCTRMVQQESAGrIPAQLLRDGDPAKVIGSLCAEHGYSTLIMSRRRIPAGTGWLTGSVTASLLHR----------- +>tr|I7LJB1|I7LJB1_METBM Uncharacterized protein OS=Methanoculleus bourgensis (strain ATCC 43281 / DSM 3045 / OCM 15 / MS2) GN=BN140_0879 PE=4 SV=1 +PEVRSILIPLDLF--VHDISDEAIDVLSTYNATISLAYITDARVIElleqaldhasteefrakkeeygrELLERTAAKLKGHGI-TTQTRMFVGHKGDDVVRMAK--NYDLVALCRRyADGESTDVSISPTVLRICQRVATPALI---- +>tr|O59574|O59574_PYRHO Uncharacterized protein OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) GN=PH1911 PE= +PTVTRILIPLDRY--SDPLPESVIEYISSFPgSRVGLIYVIDEDVCRviretigdkdaeifrekefkkgeETLNATKKLIEDLNL-NHiiSSQIKIGNKATIIEHESE--DYDILIVSRYyGATMVKTYQVSPIVFRILQNVEKPVII---- +>tr|A0A0Q9S274|A0A0Q9S274_9ACTN Uncharacterized protein OS=Nocardioides sp. Soil796 GN=ASH02_01290 PE=4 SV=1 +------LVAVDGSDASVQCLVWALHHAAVHQLTVEVVTIWPSRHTvfvhevaghfsaprwkardaqRQVIRKALAQVPRGSI--HAARLENGRVLDSIVQASA--RCELVVLGAASGDEPHPL-----TTRVAEQAECQVVVV--- +>tr|A0A1M6BAZ5|A0A1M6BAZ5_DESDE Nucleotide-binding universal stress protein, UspA family OS=Desulfovibrio desulfuricans GN=SAMN05660830_00010 PE=4 SV=1 +----RILVAYDASQSARDALTYCRELVELIADkcggkyTILVLTIEQLPACSlfssmgawkeqcakahkkqlLVHEQIVDEVKQSGLdpscitnkfvtlderdEPLEDSERKRLIAKAILKELKQGHYNTLVIGRRGVTRSDAYLFGSVSQYLLQEAKKCVI----- +>tr|C6HXJ0|C6HXJ0_9BACT Putative uncharacterized protein OS=Leptospirillum ferrodiazotrophum GN=UBAL3_92050190 PE=3 SV=1 +--YRRILIGSDLSRFPADIIEEIRKLAAHGDPifpeEIHLAFVLEalqdipidlPMAGLNLLPVAEEALGRLNLiardlgsmpTRISTGVYHGKADKILASLAAVLKFDLILVVSHGRPLINRLMTGSLPGSLVHISPVSVLVIKD- +>tr|I7Z9G3|I7Z9G3_9GAMM Uncharacterized protein OS=Hydrocarboniphaga effusa AP103 GN=WQQ_35170 PE=4 SV=1 +---------ISGQETRLDHVREAAALAQRRGAELHLMHALPEVSEgmliealysdrplsesvaGQRLADIASQLG-NEL-PIRLHIGTGEPESVLRKLLKRTQASILVVDRG--AVMRKRLMQASFNSKLADSPCLLICVPPR +>tr|A0A0Q5GH87|A0A0Q5GH87_9XANT Uncharacterized protein OS=Xanthomonas sp. Leaf131 GN=ASF73_07840 PE=4 SV=1 +---------ITGRETSLDSLRDAAALARRRGADLHLLHVMPDISEgllmdslfndqpltesaaSHWLSELAAQLQDDDL-CVRIHVAVGNPRREIAGLLKRARADVLVVEHD--AVVRRGVWRSSLHTALAKTPCVLICLPPG +>tr|A0A0F2QXJ2|A0A0F2QXJ2_9DELT Universal stress protein UspA OS=Desulfatitalea sp. BRH_c12 GN=VR64_13310 PE=4 SV=1 +KAWHGITVFYGGSSNAETALRWGVHLSEKSGRPLDLFTYADIrnaDRPDARLQASGLWDRVRPLLRTWHKIDQGGFKESLYAVD---HDALLVVGAYGHGLLKDFVYGSKMEVIQRWMPNNMLLIGPH +>tr|A0A1F3IXP0|A0A1F3IXP0_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWE2_42_42 GN=A2W94_08960 PE=4 SV=1 +----NILIPYYFDVLSDFALQEGIALSKAFKTGLVLFHCNPDESIKLRLAEIANNIISNHEIHTECFIPTGKADELMFALAHKTESILIIIGHNSNNSSLGFSLGKTL-RVMRKSRTPFLMVPEG +>tr|A0A1V6HY24|A0A1V6HY24_9BACT Uncharacterized protein OS=Bacteroidetes bacterium ADurb.Bin035 GN=BWX61_01318 PE=4 SV=1 +----SVFLILNENNFSTAALAQSIIYAKSFGAQLTI--CASPGFNKDILKKLINYVNNEFKIPAMGLQLDMPLKEWLIQASSKYEAIFFVVSLIDNKTSLGTNISQTL-HFFRNSRVPLILVPNK +>tr|A0A1Y6CLA0|A0A1Y6CLA0_9PROT Nucleotide-binding universal stress protein, UspA family OS=Pseudobacteriovorax antillogorgiicola GN=SAMN06296036_12681 PE=4 SV=1 +----RALLALSLSGNEDHVIRYAISLCERSDMDLELCHILPNTTPYvyesayfpeslypvkdpmirqaraeDKMNEIMARFNSDCI--VARTIRRGWFEDELVDLVDHHQASLIIVGRENDYRSIVKRMTSGLVSLVKTAHVPVLMVPRG +>tr|A0A170QBR0|A0A170QBR0_9ZZZZ Uncharacterized protein OS=hydrothermal vent metagenome GN=MGWOODY_Mmi1610 PE=4 SV=1 +---MKILIAVSSKEYSGPTLSVGMNISRAFKAPTTIVDVGEKInefstkdvgmaherieswdfyrPGVDVLEWAFDYLADKEFiersdieagfpkntlvdiggnrcevylkgtvcDNVNLILRNGDIIAELKDEVQKHHYDVTIIGGSQKRRM--------AHDLIQYIDSSIFVVN-- +>tr|A0A1Z9L3U7|A0A1Z9L3U7_9BACT Uncharacterized protein OS=bacterium TMED190 GN=CBD50_04825 PE=4 SV=1 +---MKFLLAISSKDFSGDTLHIGSQIALAFNAQLSIVYVGPKPkdlylnrvkqaqqnlekweiyhPGIEVLKWAFEKLKDSGFiksknlndfnpanilessgrykiilptsygQKIDLILREGDLIEQLRSEFKQEKYTIGIIGGSKQRNK--------SNDILQFLPSSIFITN-- +>tr|R4Z4M1|R4Z4M1_9ACTN Uncharacterized protein OS=Candidatus Microthrix parvicella RN1 GN=BN381_80175 PE=4 SV=1 +--MNAITVAFGTHDSSIEPLTWSARLAQHLEAPLQVLSIVAPVSAEappeffaeldqRRRQDIEQATKNAGAASADVVVLnEHKPLAAIASYVNEHQPTMCVVGTHDSHEPGGLGEGNPAHHLLHHCHVPVAMVGPG +>tr|A0A0G2ZV39|A0A0G2ZV39_9DELT Sodium/hydrogen exchanger OS=Archangium gephyra GN=AA314_07089 PE=4 SV=1 +----TVMMCVSHGQSGAGMVTLGRALTGapQEPSQLYALHLIRPTERASFHLRHDPekasgdslapligRASGLGLQVRPLSFVSTEPGPDICRTAEAKQADLILLGWHKPLFS-RTLLGGTVHEVMQAASTGV------ +>tr|Q54CP6|Q54CP6_DICDI Nhe3 OS=Dictyostelium discoideum GN=nhe3 PE=2 SV=1 +----NILLYISNTRVGTALTNIAAAITPsdeesKKKYRVKSLFLHPISDRPSSYFYSTSnniknlpaqkreaveaiqnDSQEVGLPFKPIF-inS-TDPAQDISSVAkKNQWPDLILLGYTRSEVANegisSlgqsggffggggsggsdgqAFYGKVIVKVLQTCKSCV------ +>tr|F0ZZ47|F0ZZ47_DICPU Putative uncharacterized protein OS=Dictyostelium purpureum GN=DICPUDRAFT_58099 PE=4 SV=1 +----NILLYVSTNRVATAMTHIAAAITPstedsKKKYQVKSLFLNSTSNRYSSYFYS-SnninnlppqkkeiyrslqsESNEVGVKFKPLF-vnA-TDAAEGVTTIAKRQWPDVVLLGYSDRGDDQt-vdeshhagteTFYSKLIIKTLQTVKSCV------ +>tr|A0A0H3K1R5|A0A0H3K1R5_SYNP6 Na+/H+ antiporter OS=Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) GN=nhaS4 PE=4 SV=1 +----QVLVPLANPQTQRQLLSVAADLALsdRGMGVIYPTNLLEINNDYGFDDMPVEveaelqnlhqgmarllgELRLPPAVVLPIIRSSGNVGRDLCQLADQAQADLILAGWHRSTVG-DSRLGGRVGYLLNHAPTDV------ +>tr|A0A1G0Y1C0|A0A1G0Y1C0_9BACT Transporter OS=Lentisphaerae bacterium GWF2_49_21 GN=A2X48_09720 PE=4 SV=1 +----RILISFGPALTGVRLLRLAGEISPksEHQSNITALHLTQGTDMHPIHADGYAqesfqplldEAKVSGIKIETLYKVTDDIEQEILDISDSQNYDLILIGSGKSIYK-GsllgsligmmnilsfrnilrvikgkppiikkdSLIHEKARHLIENAPCTV------ +>tr|A0A1H6API0|A0A1H6API0_BACT4 Transporter, CPA2 family OS=Bacteroides thetaiotaomicron GN=SAMN05216253_11377 PE=4 SV=1 +----KLIFCFGRPESGRSLLSIYDLLFGkqLKKEHVIAAHYTVGTDLNPLDAQHYEsesfallnqRAVELNIQVDNHYRVTDKLVQEMIHFIRKEHPDMLLLGAGSHYRPEmpgtPgailwlTLFRDKIDDIMEQVKCPV------ +>tr|A0A1J3HPP3|A0A1J3HPP3_NOCCA Cation/H(+) antiporter 19 OS=Noccaea caerulescens GN=LC_TR7375_c2_g1_i1_g.25089 PE=4 SV=1 +----RILTCFHSSRNIPTLINLIESSRGtgqKGRLCVYAMHLMELSERSSAIAMVHKarnnglpiwnkierstdqmviafeaYQHLRAVAVRPMTAisDLTSIHVDICQSAHQKRVAMILLPFHKHQRAD-gamesigHGFHLVNQRVLQRAPCSV------ +>tr|A0A1J3CRQ1|A0A1J3CRQ1_NOCCA Cation/H(+) antiporter 20 (Fragment) OS=Noccaea caerulescens GN=GA_TR19490_c0_g1_i1_g.64483 PE=4 SV=1 +----RILACLHGPANVSSLISLVESIRTtkILQLKLFVMHLMELTERSSSIIMLQRarkngfpfvhryrdgechssviggfqaYRQLGRVAVRPITAvsPLPTMHEDICHMAETKRVTMIILPFHKRWNVD-hhqdggdgnvpenvgHGWRLVNQRVLKNAPCSV------ +>tr|K7VU58|K7VU58_MAIZE Uncharacterized protein OS=Zea mays GN=ZEAMMB73_283365 PE=4 SV=1 +----RMMACFHSTRNIPTIINLMESSRGtrKRGITVYAMHLVELSERSSAICMVHKarrngmpfwnrrrngdgggdqlvvafetYQQLSRVSIRAMTAisDLETIHEDVVTSAHQKRAALIVLPFHKLHQID-ghmeslgDQYQHINQRVLHHAPCSV------ +>tr|A0A1C7MYR1|A0A1C7MYR1_9FUNG K(+)/H(+) antiporter 1 OS=Choanephora cucurbitarum GN=kha1_1 PE=4 SV=1 +----CLLSLVNKAESIPAVMALIQLMKNnpLSSIEIHALRLLELTERASAVMKYKDmqydpvlnvlftFAQLSHLHALLktHLDycLSTDYIKTVCRYRSEVNADMVVLPLMDPEA-----DLELIHELFG--iqHAPV------ +>tr|A0A1J7IAM1|A0A1J7IAM1_9PEZI Putative K(+)/H(+) antiporter protein OS=Coniochaeta ligniaria NRRL 30616 GN=CONLIGDRAFT_584407 PE=4 SV=1 +----RRLLVYLRLDSLPSLFTFITLLGAetshaaqeaaaasatedtvhirKRPLEVHGLRIIELTERTSSVMQVTEgeeyysahdpvvnafrtFSQLHDVAAAGRVAvvPVDSYPETLMSQAADVSSDFALIPWSEYGSVTedqsVpyainaserfksGTHLDFIQKTLARAtqTCNT------ +>tr|A0A1M5E002|A0A1M5E002_9PORP Transporter, CPA2 family OS=Dysgonomonas macrotermitis GN=SAMN05444362_109107 PE=4 SV=1 +----KILVSFEESIVGRKLLLIANSFVKkdQQYSEIDMVHISPGNGLYQHDMEDEEhdvfepvifASKALNQPITTIFEVASNPTRKIAKMANEGSYDFLLINAHNSIYGGkGnilgymlgvsnkilhiptriyswmtktkkaaktnsISLDEGTRSILTHSNAPV------ +>tr|A0A1T4L2X6|A0A1T4L2X6_9PORP Transporter, CPA2 family OS=Porphyromonas circumdentaria GN=SAMN02745171_00287 PE=4 SV=1 +----RILLAFGRSDTGPTLLRLAHQVFSrkDLSNGLSLLHITMSYNISVIDEETFFeenfeesieEGKRLSLNVHPIHKVSDQATSEIIHCANNGEHKFLLVGAGLNLSDSeidKsiisehqslqkfwgklsvntpeallnarTMFNDKMARFAEDSKCSL------ +>tr|M0QDD0|M0QDD0_9ACTN Uncharacterized protein OS=Gordonia soli NBRC 108243 GN=GS4_03_00660 PE=4 SV=1 +SGSGPIILGYNGSDASMAAIEATARLAG-RGAEVAVVSAVVRRGSRpqptplhdvlkaeayllsdhaavgELVRRGRETAVAHGLRPLEPIIAEGDPVRALVGAVRDLGASTVVIGRPDDP--GRRVPGPLARALRRHLPDDVDIVATD +>tr|A0A017HER8|A0A017HER8_9RHOB Uncharacterized protein OS=Loktanella hongkongensis DSM 17492 GN=Lokhon_01615 PE=4 SV=1 +TPYRRVLVAVAPGPASETAIPVIRAIA--PHSAIELIQVVPLDRDAetlcgsasgaatsvtpEQDTRAIEDLREKMGLALNTEMPdlKGDPRIKIRQKVSSDRTELIVFVNAGA-------VLDLKDSFIRTPPCDLLVCPT- +>tr|H1YAQ6|H1YAQ6_9SPHI UspA domain-containing protein OS=Mucilaginibacter paludis DSM 18603 GN=Mucpa_5443 PE=4 SV=1 +--MKPILVINDHSPQAEHAARMALLMAQRLHADLLLANCHAYEWQMlekavagsfnkdtgyhhyendlrDELYRLSHTSTGFKPE-ISPIDLSGSSEAALAGFVMGHEVEMIICGVGPGTGSRESHISSGS--LLRKVNCPILLVPYG +>tr|A0A223NQ26|A0A223NQ26_9SPHI Uncharacterized protein OS=Mucilaginibacter sp. BJC16-A31 GN=MuYL_0070 PE=4 SV=1 +--MKTILVINDYSAEAANAAKMALNIGRKVAADIIIANTVKVNEKTqvkgglqmagsstivpdepevnlvTQLESINGSEDDYKPV-ITVIDASLFSETNLAELIIKNDIWLMVKGIRNNPGanQSGYSLNAQA--VLNRVRCPLMLVPES +>tr|I4AN61|I4AN61_FLELS Universal stress protein UspA-like protein OS=Flexibacter litoralis (strain ATCC 23117 / DSM 6794 / NBRC 15988 / NCIMB 1366 / S +--MEHILVPINFTPATEISLAHAVGIAQTSHKVIIMCYFVTSTVplganavlhkreikekYKKAYMEMRVLLSQYenhtyngtgQPVMIEPLVMEGHPDDATEKIMQDNSIAMIVLSHKDSNEIKDLFLNN---KVVKEANCPILTIPKD +>tr|A0A150GUF6|A0A150GUF6_GONPE Uncharacterized protein OS=Gonium pectorale GN=GPECTOR_7g945 PE=4 SV=1 +-RPARYLFATDGSHAAHLAFCFLVNYLMRPADRVTVVTVTGTDGASEakllsGYSDYMRKHKVTGDVSVKCIDRlSNTVPEGIVEAVADHGCDVLAVGISGYGRKK---LGSVSTDISTRASCTTIIIKDS +>tr|A0A1C9W7N8|A0A1C9W7N8_9GAMM High-affinity choline transport protein OS=Microbulbifer sp. CCB-MM1 GN=betT_1 PE=3 SV=1 +APIS-ARNPVV----WQRRLKNALQLPTLAEVHEFIHDVGKP-SLEEFAEEMRksgytatvtEGenhyvelevlhgeelsfiyglqpkatlkpetdnpdkvlDDSRDDGSSDV---YFRADVHLFEGGQDYD----VMGWTKDQI-----LTDMVSQYERHLQYlhtlr-------- +>tr|A0A1Q9UQ09|A0A1Q9UQ09_9MICO High-affinity choline transporter BetT OS=Serinicoccus sp. CNJ-927 GN=BJF86_05925 PE=3 SV=1 +SSL---VGREASAVPWRLRLARTFGTVSVPQAQERMSGVVVP-ALESVRDALLeqgvqaevlVTevdpgarvvqtatlqvsgeseasgfsypvqirrtpaptfgtrsldaRDRTTRLQVA------------HPIAGGYD----LMGYDAEDV-----CHDVLDQYERWAVSsamvaE-----G- +>tr|A0A229GH17|A0A229GH17_9GAMM Choline transporter OS=Psychrobacter sp. DAB_AL32B GN=CAN34_08310 PE=4 SV=1 +IPPH-LLKPSA----WRERIDYMADQPTRDKVLSYIKETIMP-SMVEVSEKFTetgwtthvnYDainnravlelqrgdgvefwyevrlsehdtpdyytEEGADKLPQQH---DHRAEVYLRRGGQTYD----LYGYESESV-----INDIIDQFEKYLHFvnvspDILPWRM- +>tr|A0A238HDZ3|A0A238HDZ3_9NEIS Glycine betaine transporter OpuD OS=Kingella sp. CHUV31 GN=opuD PE=4 SV=1 +PSSS-MWTGEK----WRERLAHMLNQAEEKDILLFLKRTALP-AMYQLQNELIsnygfhaqvvKHfddevpavelvihketmrdfvygirsvakevaenlvad-EHLPNFQNAV---TYEPITYFSDGRQGYD----VGYMSQNEL-----IADILKQYERYLSLlgdvgQELMSHE- +>tr|A0A0X8X2E9|A0A0X8X2E9_9SPHI Uncharacterized protein OS=Mucilaginibacter gotjawali GN=MgSA37_02552 PE=4 SV=1 +--MRNIMLFIDDVAGAEALAKKALKIACQCKANLQLCNVAANMAHKkelvghngdddefletdkfglkadelGQQLQAIYYPEGTFIPAVEYCEISNFNPVIIKEMVVKHNIWLIIMDEKQLRHIKNQDTGNYALKEISSLNCPVLIMP-- +>tr|A0A1M6MTU0|A0A1M6MTU0_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Maribacter aquivivus GN=SAMN04488007_1749 PE=3 SV=1 +-DFEQVVLPIDFEItYDDTTLFKISNYITSKSTHINLLYVTKsKIPLLEEIEVLQKQFAKRlslkiPNNVSFHRVVSKKIEHGIQSFSKSINADLIIMISKDYNLLQKIFLDTTVEEVSFKTSIPLLSLQG- +>tr|A0A1T4ZUU3|A0A1T4ZUU3_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Maribacter arcticus GN=SAMN05660866_00296 PE=3 SV=1 +-GFKQVILPVDFEMaYDDATLNKIANYITSDKAHINLLYVTKsPIPLLEEIEVLQKHLAQRlseklMNTVSFHRVVSRKVEDGVHSFAEGLNANFIIMISKDYNLFQKLFLDTTVEEVSFDTSIPLLSLQG- +>tr|A0A1H4R6P1|A0A1H4R6P1_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Maribacter dokdonensis GN=SAMN05192540_2776 PE=3 SV=1 +-KPSKIGFPTDYNIfYTYPILKSLTEVLQISNATLDVVHVTQaKTNFSNTQIANKAYLHDYlkemfTGFHCFKEIQGLNIKETITTYLTDNSVEMLTMAAKNINLFQQLFFNPSKSQLNHQSSVPLLVLHE- +>tr|A0A1W6MPI9|A0A1W6MPI9_9FLAO Uncharacterized protein OS=Nonlabens spongiae GN=BST97_13785 PE=4 SV=1 +-DTHEVVLTTDYKLkYHKNQIEQFKQVIHFLQGHLCILHVAEEKELNTSESKNREWLEGQfqGIPHTFHHVTGHDVKEGVRHFIESRDSSMLAFGNRKHSFLSKLFSTNMAMEFGMFSDIPLFVMSG- +>tr|K6GS65|K6GS65_9DELT Universal stress family protein OS=Desulfovibrio magneticus str. Maddingley MBC34 GN=B193_1447 PE=4 SV=1 +--MERILVGIDASHPFWEALDRALCLGPRIQARVSVLVVFPPNEGqggeagQAILRRVESEIAAAATTgaTVELFVTEGRFDQAMVSAAGQLKTTLLVAAATGRDEQGGERETENLGRILAGVDCRVELVSPK +>tr|A0A0Q5ZJ20|A0A0Q5ZJ20_9BURK Uncharacterized protein OS=Ramlibacter sp. Leaf400 GN=ASG30_20520 PE=4 SV=1 +GLPRGILAVVDAGAGGTHAAWRAALVARDHGRPLHLVTIQprardala----AKPLLQDLAGQLEQRiQVRATTAVVAGALR-ECLVELAA--HRELVVVPWqRS----ASWSdkvLGTPPERMLRWLAAPLLIVR-- +>tr|A0A0S4PKT0|A0A0S4PKT0_9BACT Nucleotide-binding universal stress protein, UspA family OS=Armatimonadetes bacterium DC GN=DCOP10_116128 PE=4 SV=1 +--PTHLLVPFANTPEDRELLRHAVRMAQVFEAHLTVLCFVEVSRGvnleqcppekmrrgEEFALEAREIIEELGFGNYTIQTRpTHHCGFAIVEAVREYGCDMVCIAAEYRRVLGRQLLTETVETVLRKVPVQVCL---- +>tr|T2KLA5|T2KLA5_9FLAO Universal stress protein, UspA family OS=Formosa agariphila KMM 3901 GN=BN863_15110 PE=4 SV=1 +KNFKEIGISTDFDISfTEKGLSPLLDIATSQKATVSICHVMDRAKKLTSSQNEKKEALKVmlKDCSAGYFTLTGIGVsTGIRAFVQSRKLDMLCVIAKEQDFLKRLLNQSYSKSITHRANVPLLILN-- +>tr|M7MDU6|M7MDU6_9FLAO Putative universal stress protein UspA OS=Xanthomarina gelatinilytica GN=D778_00795 PE=3 SV=1 +MDLSEIGFATDLSIEnYGDDLDLLKEIAMAHNAIISAVHITNKSTNLSPDLLANKLALEMtlKPIKMDFYLINDVPVeVGTRVFSESRKLGMLCIINKKRSFFEKLFNRSNSKSISSHLNVPLIIFN-- +>tr|A0A1V3WTJ2|A0A1V3WTJ2_MYCKA Universal stress protein OS=Mycobacterium kansasii GN=BZL30_6625 PE=3 SV=1 +-----VLVGIDGSPASERATAIAFEEASWRGAELVALHAWTDAEvpgtpsrewtgltrtsWSTLQSEADETLAErlagwrdrYPDVDVERVVVVNRPRSTSSSARN--QRSWWSSEATGVVA--------------------------- +>tr|A0A1Y6BSI5|A0A1Y6BSI5_9PROT Nucleotide-binding universal stress protein, UspA family OS=Pseudobacteriovorax antillogorgiicola GN=SAMN06296036_108126 PE=4 SV=1 +---KSILLGLSLYEDETHLVRFTQSLCQSLRAKLLLTHILKPFHYYayageapvfpldtygpimdeldeENAQKLLSKIQEGLDVESDIIVKRDSLIEGIEEVAEKGKAGLIVLGSNYSNSVWQGLSTSIS--LMRGSSFPVLVVPQG +>tr|S3VE70|S3VE70_9LEPT Transporter, CPA2 family OS=Leptospira fainei serovar Hurstbridge str. BUT 6 GN=LEP1GSC058_1872 PE=4 SV=1 +----GILVAFALHSRGIDLLRLANGLfpAGNKAKEVTALHMSPDSSIsgkvaqryeKTSFEPLHKLSKELGLKLKTLYKPSDNVAKDILRTIQSGNYNMFLTGGAR-SLFSDDVLGGKIRTLLSESNGNA------ +>tr|A0A1M3E4N7|A0A1M3E4N7_9BACT Cation/H(+) antiporter OS=Bacteroidetes bacterium 43-16 GN=BGO31_05365 PE=4 SV=1 +----KVLYAFDEPEAGRQLVKIGAAIfnG--AETQYTAAHFAEAEDMhlydiaayeNKVFQPAVQVAKKQDLSLKTHFAAAGDVDTALIEKTHKGKYDMLLMECSP-SIYDGTALGkilgftsriinldklyrsiarkaevaswnvidESISSIADRLNIDF------ +>tr|D3DIU8|D3DIU8_HYDTT Putative uncharacterized protein OS=Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6) GN=HTH_1297 PE=4 SV=1 +PQISSLCIPVDFSERTLKQWNFLEYLKEHFSLNFRLVYALNVARLKnklsseeyqkllkDKKDEAVHLLKEmFGDKQLELDLLEEDPYNGLSKHINSGDYNLLLISKRGKGMAK--FVGSVSQHLTRTVRCPLIVL--- +>sp|P36204|PGKT_THEMA Bifunctional PGK/TIM OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) GN=pgk/tpi PE=1 SV=4 +---GNWKMHKTISEAKKFVSLLVNELHDVKEFEIVVCPPFTALSEVGEILSGRNI--KLGAQNVFYEDQGAFTGEISPLMLQEIGVEYVIVGHSERRRIFKEDDEFINRKVKAVLEkgmTPILCVGET +>tr|A0A1Q9P009|A0A1Q9P009_9ARCH Inner membrane transport protein YbaT OS=Candidatus Heimdallarchaeota archaeon LC_3 GN=ybaT PE=4 SV=1 +-DMDNILVPVSGKSYETQNLLVTAYLARKYRVKITLLHIAKNGKIgknkknGKAFKTAESIFKEFKV-EYDTVTRPGnHVDRQIVDVYKNGNYQLISLSSRRKHGFfTRMFEKSISANVVKNVSCSVLQVHPP +>tr|G6F1J7|G6F1J7_9PROT Uncharacterized protein OS=Commensalibacter intestini A911 GN=CIN_14930 PE=4 SV=1 +KTPQNSMLAFSGSEISKRLVKHLAQEKYCLSIPLYLVMSGKPTNErQKELDWAHQILENAGYNVISSFILgGGTIEDTIIRTVQEQCIDILFMSAFENNSLYNLIFGSKTVDLLRYLNIPIL----- +>tr|D7VZW6|D7VZW6_9FLAO Uncharacterized protein OS=Chryseobacterium gleum ATCC 35910 GN=HMPREF0204_12965 PE=4 SV=1 +----KILLPVDFYSTSDNTFLYAIAFAEQFNADVHILTVLEDTAEPEQNNQFRKGLKEREIelfyqqiksykntseVNLSFGLTKESFTDAIINYLQNNAIDFLIIGYDTNGIKSNSQIRQEISEKNYKVNVPIIIVP-- +>tr|Q3SFP5|Q3SFP5_THIDA Uncharacterized protein OS=Thiobacillus denitrificans (strain ATCC 25259) GN=Tbd_2608 PE=4 SV=1 +RPYRRVLALIGFDADDALVARKAAAFANLNGAELDFLHLIAPDAVldggyaggspaatasaleQAALRRLQFLAAQCGAGEARCHAVHGPRRQRFTDHLAAREAGLVVTT--------------------------------- +>tr|A0A1M6NIN1|A0A1M6NIN1_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Maribacter aquivivus GN=SAMN04488007_2069 PE=4 SV=1 +NHPKEIVLTTNFNTKiKSSEIKYLVEIAKLSNANIQVLSLTQPNKLSFSQKRNKVFIRSQlkGVEYKFNTLRNVKMAIALSCFVEIRASNMISYVDKKPSFWERLgFGKLSLSKLGYYANVPVLALHA- +>tr|A0A1G7E1A4|A0A1G7E1A4_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Cellulophaga baltica GN=SAMN04487992_1029 PE=4 SV=1 +NQPEEIVLATNFNTDfDISEIKYLVEIAKMSNARIQILSLTDDSVMTAQQKNNKSLLEKYlvGLDYIFNVLHNVKMSAALSCFVEIKHSNMISYVDKKPSVWETLgFVRPSLGKLGYFNDVPVLALHG- +>tr|A0A1M6GC06|A0A1M6GC06_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Pseudozobellia thermophila GN=SAMN04488513_102756 PE=3 SV=1 +TDLKKLVFATDFKHAfSPIELLPLIDIAKLWNATLNVVHIKTEESLSEEQETNKAILRNVlkGSKHLFFEIKQRdSVANTLIEIEKtNKSMGMMALLMTDHGFFQKLVRPNIIKSVAFKTEKPLIVLPQ- +>tr|A0A068U895|A0A068U895_COFCA Uncharacterized protein OS=Coffea canephora GN=GSCOC_T00017969001 PE=4 SV=1 +---AVYYVALVqGGqqgnggskraadqdSASMDALLWTLNHAATanndptTTPLLFLVHVFPEIKHiptplgmmplsqvnpeqkeiymaqergkrTQFLDKFLNACSSaAEVKVDTILIESDMEAKAILDLIPILNIRKLVLGTTKAilRKVRSKRSASgVIDQIVKGAPefCEVKVI--- +>tr|A0A1U8GL57|A0A1U8GL57_CAPAN U-box domain-containing protein 36-like isoform X2 OS=Capsicum annuum GN=LOC107870100 PE=4 SV=1 +---DVVYVVVWnKInnvsdheGPSMDALLWTLNHVVInqNSTNVFLIHIFPQTNFiptpwqvneehkekymtqerskrRQFLQKFVDICSSSKVKVDTILIESDMEAKAILNLIPICNVRKLILGTTKAnlKRMKSRKGNGTTDEILQNAPefCEVKII--- +>tr|A0A106BSS6|A0A106BSS6_THIDE Uncharacterized protein OS=Thiobacillus denitrificans GN=ABW22_03485 PE=4 SV=1 +KTYRRILVPIPANGQGDILLQRAAELAQGPRTQMLVVRVLDTRSGFepdgpaavlpgeaaarrapDVKKRLELQLARNNLGWAEAKVVWGETKVLLADVIRTWEPDLVV----------------------------------- +>tr|A0A090P451|A0A090P451_9VIBR Universal stress protein E OS=Vibrio ponticus GN=JCM19238_811 PE=4 SV=1 +SIYNNILVVANINSDEQPALARAMQLAAksRSRSHVTFFLSIYDFSYDmtsmlsidernamrkgvihqreQWMRSVAEPYLNDSIDFDVVVVWHNRPYEAVIAQVFAGEHDIVIKGTRKHDVLESVIFTPTDWHLLRKCLRLF------ +>tr|A0A1M5WAZ9|A0A1M5WAZ9_9BRAD Nucleotide-binding universal stress protein, UspA family OS=Bradyrhizobium erythrophlei GN=SAMN05443248_6457 PE=4 SV=1 +MTYATVMVSLALDRSNDTRLEIAGQLAKRFNVVEIAEDDVHRPAELSGVNDVVAWLSRHGVVaSGQAPSECGDVPTQLDRIASELGAGLIIAGAYGHSRLREWVFGGVTKGLVNPSGRCTLLSR-- +>tr|A4A1T6|A4A1T6_9PLAN Uncharacterized protein OS=Blastopirellula marina DSM 3645 GN=DSM3645_29491 PE=4 SV=1 +-ELDRVLLIYDGSNASSRSIRSFLsQHAAYLGNQYRLLCVGEAASPQSGAYRAMLQYCRSRMETLEVGCLPGSPVKTAAKYAQKWEADLLVLGVARTSSWWGSPFGQLGSDILQHTELAI------ +>tr|A0A1P8F7Q6|A0A1P8F7Q6_9CHLR Universal stress protein family protein OS=Dehalogenimonas formicexedens GN=Dform_01176 PE=4 SV=1 +--IKRILVPLDGTPYAQQILSVARRIGENFKADIVLFSAVKSAGRtaadiENQKKEASKYLDGvaamlYGLNVTTIISEANDFTTAIDWAAFQTKSDMVTMVTN--SRVTEWAENSISRKILNTGATSMLIVHR- +>tr|A0A0S7YWS3|A0A0S7YWS3_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium SG8_13 GN=AMJ54_03420 PE=4 SV=1 +-PDSRYVVCADGSPSAQRQFPLLKGLLHSIRGPVDLVWVKKPDvkkqdieAAEKCLQHAWNWLETCDRAGAVHRLEGENLVDLIVDAAG--TSSVIVMGASLRHDVYRRMLGSLPMQVLSKTKSSILLAK-- +>tr|K1ZU53|K1ZU53_9ZZZZ UspA protein OS=groundwater metagenome GN=ACD_73C00798G0007 PE=4 SV=1 +-GIKNVLVLVDEFPFSLDAIKQGVQFAADLRATLYFFHLNDPSGEtlnsFESIKQSLQIPPHQGGD--QWLIEEGDFFEMIDQVIAEHQIDLVVFGTHINADHPE--SGQRTLAIINKIAIPCLILHPH +>tr|A0A1Q9D3B5|A0A1Q9D3B5_SYMMI Uncharacterized protein OS=Symbiodinium microadriaticum GN=AK812_SmicGene28871 PE=4 SV=1 +----RVLVSVDGSDQSSCAFEWVLHGFTQSDREtdLLIVHYYDDTKEYlppkwrrnAIQADAEAKCTSYLVSkRYAISVRQRSPGVKIgvllCQDIKDQGTSFCVMGFAGRKGKDRHIIGSNVLEVMQRGKCSCVVFKEA +>tr|A0A0M9E149|A0A0M9E149_9DELT UspA domain protein OS=Candidatus Magnetomorum sp. HK-1 GN=MHK_007849 PE=4 SV=1 +--MKKVLLAINGVTPSTKIFHYALQLCQRTTATLVVLQIIGKRHASgyfdkirkkagavkqffensmiaatyaeagehdialeliglakKNIQKMLQECRNAGV-SYQLVFKKGEPEKEIINYVCqNRDVIFTIYDSPIIQQADKDqlkERKRQMSIMEKNLPTPLFVCNDE +>tr|A0A1J4V530|A0A1J4V530_9BACT Uncharacterized protein OS=Nitrospirae bacterium CG1_02_44_142 GN=AUJ60_02095 PE=4 SV=1 +--KEKLLFVTKGGEDCDKGFSYVLELAKSLNAGIELLMIYGKGVLDkyedvmaavafaeagdhetvrelmnaqgkkikdtaeKKINELTEKCRDANI-DFSSEVKTGEAIEVVKDFIKnKPCIDMILLSPNLSGD----KKLLDVRKMLKNITKPIVTMMAA +>tr|A0A1V5G2H5|A0A1V5G2H5_9BACT Universal stress protein family protein OS=Bacteroidetes bacterium ADurb.BinA261 GN=BWZ06_01223 PE=4 SV=1 +SEMNKIAFLTNFREREFVAFERLMKLIGDRQIEVYILHISKKDDLWNeiKLSGMKNYLKEKyPLLEIHYKLLDsanDRLEVAIDNFVKENQIDMISMSSSRRNIFARMFNPGLARRVIFHSKTPLLVLKN- +>tr|A1SI72|A1SI72_NOCSJ UspA domain protein OS=Nocardioides sp. (strain ATCC BAA-499 / JS614) GN=Noca_1997 PE=4 SV=1 +-----VVVLCDGSPESQSILAYAWGQADRRGLPLTVVHCLPDPPADlhprdislmdatarmeaslgpsllgferLLLSDLVRDMRSRWPGVDVRLVVEDDAIDRWLERAR-QQADLLVVGARHARRLSELVIGSSTPEE---VECVTVVLPL- +>tr|R7B8B9|R7B8B9_9CLOT UspA domain-containing protein OS=Clostridium sp. CAG:505 GN=BN684_01391 PE=4 SV=1 +TKKENILVLVTAGKESKRFMELAKDAAEAGNGDLYILHVaqgeniLESGEMY-EMQRLADYGCRLGG--QVCLCCEQDVAAYISRFAREKDITGVLLE--------------------------------- +>tr|A0A142HW04|A0A142HW04_9SPHI Uncharacterized protein OS=Mucilaginibacter sp. PAMC 26640 GN=A0256_17385 PE=4 SV=1 +--ATNILIPTDFSLTSLKVIPALLQQQPAQQFNIVLVNFLGlsdsitdllmlsrrsrereliTQEFMDECTKLSRQYADQIL-CLQTEFFYGTTIAVFKNYLEAREITQIAKLNNYKIEKLTT-LSYDPDLLLERSKYKVVSLAP- +>tr|A0A0D0GHB1|A0A0D0GHB1_9SPHI Contig57, whole genome shotgun sequence OS=Pedobacter sp. NL19 GN=TH53_13420 PE=4 SV=1 +--MKTILIPTDFNEASVYLSENILKNFKNESVKIIFFHAYKltdsisdllmlsrrsteygqiPESFHRACYDFKKTHQGKIA-AIGIEYFYGSTMAAFRNFAEAHEVDFIYCPEAYSFRQISK-YSINPDVFLNKSGIPVINTVM- +>tr|A0A1G3XV10|A0A1G3XV10_9ARCH Uncharacterized protein OS=Thaumarchaeota archaeon RBG_16_49_8 GN=A3K61_03070 PE=4 SV=1 +----PIMLPLAFESREWNTVHIALFLAEYSGSQVNILHVNSRIDNTEKRDEFLKKLKSIAAelkikysvnyaKAKSAEPGVSEIADTIVSQSEKMGCQAIVMSANRESFFRE-FFGRISDKVARKSKRTVLLV--- +>tr|A0A0C1TPY1|A0A0C1TPY1_9CYAN Uncharacterized protein (Fragment) OS=Aphanocapsa montana BDHKU210001 GN=QP59_12135 PE=3 SV=1 +-EIDDIAFAVNYQDEEVEAFQKVVDICRPFNAKIHCVNVdlSHTEDYRKEMDQFKEKLVAYDN-TTFEVIESTDIREGLTKYMETHSVDVLVMVTHKRNFFQELLRYSHAKEMSYHCNMPLLSIPSH +>tr|A0A0M0KBY3|A0A0M0KBY3_9EUKA Uncharacterized protein OS=Chrysochromulina sp. CCMP291 GN=Ctob_011840 PE=4 SV=1 +--PKKFVVAIDGSKLGFRAAKLAACFCDvRAGDKVKMVIVrtgkLDATQANALLKNAETMLKEGCFPQMNIdraevlEIQTGkSLAETLCSAAAADKGGMLVMGAGGMRLEEEWklkkkttpaaMTGSVALECMAKCKVPVIITKP- +>tr|A0A1G0AHB1|A0A1G0AHB1_9EURY Uncharacterized protein OS=Euryarchaeota archaeon RBG_19FT_COMBO_69_17 GN=A3K59_06350 PE=4 SV=1 +TPLQRLVVLTSPIWPLSGIDELALILAEEDHPAIEVLGLAGDPAEAERLKQEAESFLAeghaRGHSIEHRILYSRQWESVALQESA--EASVLLVRASSPGGLRKFALGPVEDRIVKLARCPVLLLR-- +>tr|A0A1F9Z760|A0A1F9Z760_9EURY Uncharacterized protein OS=Euryarchaeota archaeon RBG_16_67_27 GN=A3K66_00595 PE=4 SV=1 +ERPERILVMNAPEWHVSYATGYAILLAKKHKARITVFTAAQTDTEMAKETAYSARLAEmcrtHGVAFEEKFLKTRSIADAVVAEAA--TYDLVVLGASSEWRLTQFAFGPMQDQIARRIAAPTLMVR-- +>tr|A0A1F9Z5N0|A0A1F9Z5N0_9EURY Uncharacterized protein OS=Euryarchaeota archaeon RBG_16_67_27 GN=A3K66_07650 PE=4 SV=1 +RPLKKLVILTSPIWSILGIDELALVLAESDLPTIEIVSLAADPSDAERIKKEVAPFLEtchsRGIAVEHKVLYSTQWESVALHEGA--DASALLIRASSPGGLKKFTLNPVEDRIVKLAPCPVLILK-- +>tr|A0A0S2KBJ6|A0A0S2KBJ6_9GAMM Uncharacterized protein OS=Pseudohongiella spirulinae GN=PS2015_811 PE=3 SV=1 +NKMDRILVIVDPDNDKDFVIERAILLAFYYRAQVLLLmnkpNVLDQQDaatssltsrffssqkklfaehYQAKLDALKERFEAQGISAETQFSTDKNSAAMLLRKIREFKPDITLKSVQQQGRLARILITNTDWKLVKNCPYPLLLVKA- +>tr|R5AQ38|R5AQ38_9BACT Uncharacterized protein OS=Prevotella sp. CAG:1031 GN=BN456_01294 PE=4 SV=1 +-HPPRTLITVANPITAPSLVELAMMIHQgGKSTPDSPIYALYvrGSDHSDasraigrnALSVAEKAAAAVDSTLIPIERYDVSITAGVLNTVAERDISEIIIGLHGRTRITDSFFGQKIEQLVRSTNRMIVVSR-- +>tr|A0A0E9ED82|A0A0E9ED82_CHLTH Uncharacterized protein OS=Chlamydia trachomatis GN=ERS095036_03343 PE=4 SV=1 +-DDEHILVPIKYPNYAEQLIGLAILMKSrKLNRPLTAINVVYEDEQMRvnqekgkhLLEQVTRYAAGSDVQVQSQVRIAVNIANGIKHAFQEFHANEIIIGMHTHAEVSKKFWGQFHQSLFNGLNCQIIMAR-- +>tr|A0A1D8MY72|A0A1D8MY72_9GAMM Universal stress protein UspA OS=Edwardsiella hoshinae GN=A9798_08235 PE=4 SV=1 +-MYSNIMILLDLkaaSQADAQLLDKGMQLADRFDASVHPVHVVldiepgengNQSLYFKQLEEQANNLQHARGAacPEIAIIISNDFSSSLQDFIRQKKIDLIILGHHNSAFAQKFVsFLSVAKNTIDTINIDTLIVPLS +>tr|A0A0F2NK40|A0A0F2NK40_9DELT Uncharacterized protein OS=Desulfobulbaceae bacterium BRH_c16a GN=VR65_08735 PE=4 SV=1 +AERQRVLFYNDGSSLSLGTAKWFVGKHNLSKMSIVLLMVATQDREEMLADTMADKqqrereqarkqsfidirqvlieggIPEKNIETVVTTVNEKVPIsDKIIEYLSEHEFDFLLLCKHNKRKSEEFLFGDTAIQVLRKTTTPLLIVKGT +>tr|A0A1E5HB21|A0A1E5HB21_9ENTE Uncharacterized protein OS=Enterococcus ureilyticus GN=BCR24_03195 PE=4 SV=1 +-MYKKIVTVVDVFGEPNGVLAEVITMSQRENSELHLLINKPEIEaleqlnylpydsgmympyeydmikendenYQKDVDKVISKVKAEGVDKLVTTIYSGSTKSFINKYIEKNSMDLIVLGSYD-ELLSKRELESVAKHVIKNTTSNLLILR-- +>tr|C5X6K0|C5X6K0_SORBI Uncharacterized protein OS=Sorghum bicolor GN=SORBI_3002G136800 PE=4 SV=1 +--GGKLYVAVGKDrKDGKSNVSAAqSLGLVGGDLKLVLLHVHQPADRImnglgckvlasqleekelkayrqieqeemdRLLNTYVNHCRSyLKVEAETLIIEKNNVANGIVELINQHRITKLVMGMSSFSTKRKVPKSKVAAIVHQQAKpyCQIFFI--- +>tr|A0A136K239|A0A136K239_9BACT Uspa domain-containing protein OS=Chlorobi bacterium OLB4 GN=UZ04_CHB001001429 PE=3 SV=1 +-DIRKIVFYSDYSDNELNDLAKLSAIFVKFQPKIVCVIFKETRQElesETIYNIENQIRRANDDCEFEIKkIVTDDEIESLNTIAQYDSADIIAITTHQRNLIDTFFNPSKAKQLSFNSFIPLLAMS-- +>tr|A3QEY7|A3QEY7_SHELP Uncharacterized protein OS=Shewanella loihica (strain ATCC BAA-1088 / PV-4) GN=Shew_2169 PE=4 SV=1 +-SYQRLLVVVDEHDFSLKAVSRAVYLASKTHAAIIVMMLEHSHFVNRLVDtfeadgnegqtqpltkerklsclnAFISQAAQSGL-SISKASIACHSSDDVLQFCDDFKVDAVILAASRHKLWNWLTIKPLDVRLIRESSRPVVVVKDH +>tr|A0A1T5B637|A0A1T5B637_9BACT Nucleotide-binding universal stress protein, UspA family OS=Dyadobacter psychrophilus GN=SAMN05660293_00041 PE=3 SV=1 +SGFKNIIYATQFDPQETDILHQIKVLTEQLGAKLILVKVnsFHEPESHANQAHMFRTIQELDMADVDVVIVEDvSFIEGINKFCDRQGADLLIVSNRERHFLQQYLTNpSMTKRLVVETHLPLLVYH-- +>tr|A0A1A9I3M8|A0A1A9I3M8_9BACT Uncharacterized protein OS=Niabella ginsenosidivorans GN=A8C56_09440 PE=4 SV=1 +--FYKILFPVRDVEGVKEKLVHSRPFIQKDNSELHIVCLGQPDSYKVNEVIELAQNQQIQFSISDFDADSKkNIAPGVILAAKERQADMIVINATSEKQWYNIFGENYTEYILKEAAMAVLSITH- +>tr|A0A1W9V7M3|A0A1W9V7M3_9CHLR Uncharacterized protein OS=Anaerolineaceae bacterium 4572_5.2 GN=B6243_07990 PE=4 SV=1 +GSPQRILIPVAGGPNAIQAVEIAHRLN--PQAEITLLFVAT-RHLEAEIDVGRKRLSAVsdffpDIKTIHEVVVADNPIKGILREAKD-GYNLLIIGaSAEKNIFDRFIFGNIPKAIFHRSPIPTIILR-- +>tr|A0A0H3I9E4|A0A0H3I9E4_PECSS Universal stress protein A OS=Pectobacterium sp. (strain SCC3193) GN=W5S_3461 PE=4 SV=1 +KIYTHALVLVQGKEDGVPLLALAATLSRLLQMKITLAHICNDYREMnyisdglmddavskdvvQVKALFSELASSVTEHVDARELVTMRRFEEVQKCITDTGVDLVIAGHRNRFMG---ALTSRSAEYVNHLNVDVLI---- +>tr|Q1JZA5|Q1JZA5_DESAC Uncharacterized protein OS=Desulfuromonas acetoxidans DSM 684 GN=Dace_1524 PE=4 SV=1 +MDCQTIVVNYTHPDRDAEALSTALELAYRHESELLLLHSNGACckeacqrnylFSEEELVQQVNKANGYGVPVVVKIVDEQSPLEEAIRHLD--NHDLLVVGDSHADCFSNRVNNVSASRV-------------- +>tr|A0A200PPS5|A0A200PPS5_9MAGN UspA OS=Macleaya cordata GN=BVC80_23g8 PE=4 SV=1 +-----IVVAFDDTAESMVALEHVLNFSAKKPFNKIVIALIQSPEQgsvaceeEVLTQKAKELCISKSVKDmPHFEVVNGDTMTVLCEIAKKHRARVLAVGGHY-GGLAAGSGDLEGVALVNAAPCNVMIVPRN +>tr|A0A1W9UDQ5|A0A1W9UDQ5_9CHLR Uncharacterized protein (Fragment) OS=Anaerolineaceae bacterium 4572_32.2 GN=B6I35_11675 PE=4 SV=1 +-MFADLVVAINGAEAGWRALEHALFVAQHEGARVHGLHVAASETQREskdtqtIRVEFDRRCQEADV-PGELAVEVGKVPRSVCWRAR--WADLVILSLSYPPAARPiARLGSGLSAIIRCSPRPVLMVPET +>tr|I4VI44|I4VI44_9GAMM Uncharacterized protein OS=Rhodanobacter sp. 115 GN=UU5_20800 PE=4 SV=1 +TRPNDVLALVTSTDPWGPSVDAAIALAARWAANLTGCYIDPSLRHAaepdreapglpqlhdmdhAEHAAFASHAHDLGVRDARWTVTRRNIPLTLRTLGA--WHDLVVVEHDIVAGDQL---LDILGEAMLTSRMPCLLLPPG +>tr|A0A137P2I4|A0A137P2I4_CONC2 Uncharacterized protein OS=Conidiobolus coronatus (strain ATCC 28846 / CBS 209.66 / NRRL 28638) GN=CONCODRAFT_71613 PE=4 SV=1 +SRKRKILFVYEEPTDSRQSFEWCESNLFRPGQDYVCLFAIDPNAnkfmdtslfwtaaaedyevedserdkikkenfVEKELEAIKIKLSAKNIPCQKLQSLNGDPKTLILKQAENMLADLIVVPPSHPNYFSKTVFGTLEDYIVKNSLCTVVV---- +>tr|A0A1F3SY20|A0A1F3SY20_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium RBG_16_40_8 GN=A2Z20_08710 PE=3 SV=1 +SEIKNIMYATDGSDESFYAFLKLVVLAARLKCSITLLTILPTPTRWarpyvrfnsvrytkmvlkKFSTWILKAKKKGVIAYVEVVRSEENVVQAIVGVAHK-KTDIIALSARSTAAPLATIMG-VSHKLVYLAKEPVLILKS- +>tr|M0MK22|M0MK22_9EURY Universal stress protein OS=Halococcus saccharolyticus DSM 5350 GN=C449_04807 PE=4 SV=1 +-------MAYATGSVRrfgacEDGAGSRPRVRGRTNEDLLTLIVVPPDEVFARNRGWITSDEAFDPERVGSELetavnevapdvtvrieateemsslasTEMDISRTIRQVAHEIDASVVFVGSENAGRVTSP-VTSVGTPVSKDPGYDVYIVRHA +>tr|A0A0L0HMK6|A0A0L0HMK6_SPIPN Uncharacterized protein OS=Spizellomyces punctatus DAOM BR117 GN=SPPG_01737 PE=4 SV=1 +---RKILYCLDDTEADYNHLEWVLKHYLHSNDELTAVNVRHTPmptgrsldawaeykhaekdkAYKDIQVKLQQVCSKAGKSfPLTVIVEcEEKAGKYLVNLANDTKPDVILVGSLERKGIiSRLFHTGVGHYVAKHASMPVVAVKD- +>tr|A0A136P710|A0A136P710_9BACT Universal stress protein family protein (Fragment) OS=Chlorobi bacterium OLB7 GN=UZ07_CHB004002570 PE=4 SV=1 +---MNVLLAFDGSKSSVAALHDLATAGLDADTRFLVVTVAEVWHPLepesleqeplpefiptglrslherssrelsrafQIADEGADLLRNsFPAATINAQAYADSPSLGILAQAEEWRAEMIVVGAQGRSMLGAIAAGKRLAQSVGRGALP------- +>tr|A8TY69|A8TY69_9PROT Transposase Tn3 OS=alpha proteobacterium BAL199 GN=BAL199_22817 PE=4 SV=1 +---EEVVIGLDGSLAASNAFKSYVRMGLWARARLHFVHAVEDHWPdreaaiSSMMDDALAYAHRFGR-RAVAHVMAGSTLDAMNRIIQETGATAAVLGSNRRRLFADRRLTATTKKLIRDNGMSVLIV--- +>tr|W5W9K7|W5W9K7_9PSEU Uncharacterized protein OS=Kutzneria albida DSM 43870 GN=KALB_3847 PE=4 SV=1 +---QPLLVGTDGTASSEPALEWAFAAADCIGCGVRVVFSPAAATEsaklrESMLTTVTALTAHHRALDVRLHSRDSSLLEALSWHSQ--SASMTVLGPRNGTVTAA------TERVLLRSNCAIVLVPQ- +>tr|A0A150G9H7|A0A150G9H7_GONPE Uncharacterized protein OS=Gonium pectorale GN=GPECTOR_46g284 PE=4 SV=1 +-PQNVIVVAVTDDPASTLAVRTAMAIMKPGADCLHVLTIAKDISAtaQAVARNVAERYESmasatLGDVRSIVQVKQKSIVEDILEYIESVRAMLVITGSMSLAAVQTSVVGSVALSLARDCTRPILVVKSN +>tr|A0A1J5BBC1|A0A1J5BBC1_9BACT Uncharacterized protein OS=Armatimonadetes bacterium CG2_30_66_41 GN=AUJ96_11135 PE=4 SV=1 +FPFKRLLVPVAGPVNVELIADIVPALKRAGEAFVTFMQMAPPEADQAAARELLRALLAEHNLAEAGELVvraTENVQRALVRESA--KYDLTVVGAPRQHLFAR-IFGDVAERVARESDKSVMIIRG- +>tr|I0I8Y9|I0I8Y9_CALAS Putative universal stress protein OS=Caldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1) GN=CLDAP_36870 PE=3 SV=1 +----RMVAATDGVVFGQRAVKLASELQPLLVGDLTVVVIASEREGAERAQQVMVETAAmlATEPKPELVPLVGYPDEVLLKYLETHPTDLLIIGAFADRGAGGvSAVGPTAHRIVQEAPTSVLLVKGH +>tr|A0A1B2E036|A0A1B2E036_9BACL Histidine kinase OS=Paenibacillus ihbetae GN=BBD41_12445 PE=4 SV=1 +-----IYVLVGSGPESERIIRRGFRIAYRLKAAWYVTPLPDRA--edcKPSMPAR-DPIQAMterlgGIFRPLELLgkRVYDLPAILIAAADEVKATQLIIAQPPGNGFPGASQMRFAKQLLRRARhMDVLVI--- +>tr|A0A077KJ32|A0A077KJ32_9FLAO Putative universal stress protein OS=Chryseobacterium sp. StRB126 GN=CHSO_2369 PE=4 SV=1 +NSIHNIVIPCDINGiKKLERLFHHKSIIQKHDVHLSFLNINTKEKTEInsDKKKELEDYIRQHLTEIPSSIHysyDENVINGILTFAASNNTDLIIALPGKHSFLYYMASRSISEGLYQNTNLPVLILK-- +>tr|D7W1U3|D7W1U3_9FLAO Universal stress family protein OS=Chryseobacterium gleum ATCC 35910 GN=HMPREF0204_13373 PE=4 SV=1 +TPVKNIFIPCDINGiKRLERLFHHKSLIHKQDVHLSFLNINTREKEDENKKKELEDYIREHLTEIPSSIYyshDENVINGILTFAATHEADLIIALPGKHSFLYYLASRSISEGIYQNTHQPVLILK-- +>tr|A0A0Q5U1S4|A0A0Q5U1S4_9SPHI Uncharacterized protein OS=Pedobacter sp. Leaf194 GN=ASG14_12280 PE=3 SV=1 +QPITHAVVSFDEHSsTEIYYLNRLKHLQNNKNPTP-FEREKPGyhPEDIVpeSH---NYTLLNSILRSFRYYVYeqgTYDQPIGLSKFADSYYSQLIIAMPGNKGFFYNLTHKDISEKLVMDGHKPVLVLP-- +>tr|A0A061PD46|A0A061PD46_9BACL Uncharacterized protein OS=Geomicrobium sp. JCM 19039 GN=JCM19039_2592 PE=4 SV=1 +TDTDPVLIFLDFHEEALSCVTKGATIAEAEGRDIVLLHGIDMRKYTvverndptlrtqiisertEWLKTFEHQLRQNGQHVRATDLTFKDPRKIISAR----YAPFIVVALKRVHRSAK-IQKSLSDVLIDRPPCDMLIVH-- +>tr|A0A061NPG0|A0A061NPG0_9BACL Uncharacterized protein OS=Geomicrobium sp. JCM 19038 GN=JCM19038_228 PE=4 SV=1 +MPNLPLIIYVDYGNHSFAAVKKGATIAKQRNKDVILAHSIDQRKDSvtdrndiqskqqliqqrtAWLNDYKAYLLDEGIEVINIDLTFDKPSKRINEL----NADLIVAVKT---DRWG-IVKHYSHDLFQNPPYTLLGVH-- +>tr|W8EYJ7|W8EYJ7_9BACT Uncharacterized protein OS=Hymenobacter swuensis DY53 GN=Hsw_1242 PE=4 SV=1 +-------VLTDFSAAATNALHYAVVLGRHVGGQVRLWHVLPEAAGFdapyfgglrearpvaeaQYLLQELVKRVQQHL-PCSAALITEKPTQKLTALIGTGSGNVVVVGNGNPVKAMRHAGTSTALHLIKTLAQPLLVVPNT +>tr|A0A0W8EMD0|A0A0W8EMD0_9BACT Uncharacterized protein OS=Cytophagales bacterium MC1A GN=ASU33_19250 PE=4 SV=1 +--------MADFSGAAANALEYASFLARQLtarqlSVRLRVLSVAADLSTtqglSaaptlpplellNQRLALLERLQNASI-PYTHELLQQPVAECLPDMMSAALPTVFICGRTD---TTAPSAEQTLLHLIRLVTHPMLLVPEQ +>tr|A8HRL3|A8HRL3_CHLRE Predicted protein OS=Chlamydomonas reinhardtii GN=CHLREDRAFT_187858 PE=4 SV=1 +-PARAVLLAVAMDEASLAAVNYAIHELYRKGDQFHLVHVARILSPSitihhqyhatynvpelgpgidqrAFLERLKEEIKDKFTNPMDALGIPHNlhlfldtdnapasaVCETVFKVADQVDAAMVVLAAHGKGeegsrdPLLGLYLGSVADFATRNSARPVLVVRS- +>tr|A0A0Q9Z8D5|A0A0Q9Z8D5_9FLAO Uncharacterized protein OS=Salegentibacter mishustinae GN=APR42_04570 PE=4 SV=1 +--KMEMVLATRFDKSfSIAEINFLIDMTKKFKASIRILYIQDTEDLSEEQENKKEELHEHfEKISHSFHTLTNiEVTKGIHSFIQSRNSDILVLNHKKRGFFRNLFSKSLLKELGKKPQIPIIFMPA- +>tr|A0A1V9ZR02|A0A1V9ZR02_9STRA Uncharacterized protein OS=Thraustotheca clavata GN=THRCLA_05962 PE=4 SV=1 +------------------------------------MQQQGYPQQYDQYGQPQ--------QQYSQpqqqyg-----QQQQY---GQPQ--------QQYGQQQQYGQPQQYDQQYAQQaqygqapqAAYgAPNQYGQGY +>tr|A0A0F0GY48|A0A0F0GY48_NOCAE Uncharacterized protein OS=Lechevalieria aerocolonigenes GN=UK23_17635 PE=4 SV=1 +--------------GGEGVLRRAITFCRVRQVTrLRVLTRPYNGAAGSLDATADLVHAACPGVIVELVRETRSVGEEVRLF----PSDLIVVSGREGAAAEG--LQPAAGAALRQARCPVLFSCS- +>tr|A0A151E1L9|A0A151E1L9_9EURY Uncharacterized protein OS=Thermoplasmatales archaeon SM1-50 GN=AYK25_07180 PE=4 SV=1 +-LFRSILVPISSEFYPPAVFQISAFLAKAFHSTVTSIYITEKRILDDfdrlsdahlsfyereeaqhnirskhlaqaeqiVFRDAKGFFKKREI-PLQTKYLEGEFSEVIKNEIETNHYDLIIMGYGRACLIDY--------RLIDEISLPIWIESGA +>tr|A0A1Q6DRV2|A0A1Q6DRV2_9EURY Nucleotide-binding protein UspA family OS=Candidatus Methanohalarchaeum thermophilum GN=BTN85_1755 PE=4 SV=1 +----KILVLLAYPEIQENLINFAKASANSYkESSIIGFNFINLPEQTpltrrdklnspkveipdkkiveiqkAILKIARDKITSDNFDFDSKAMAGRKFEKTVINYVKKQNIDQIYMGWDGERSQNKLIFGSKVDKILKYVPCKVNIIKPG +>tr|A0A1W9R852|A0A1W9R852_9BACT Uncharacterized protein OS=Candidatus Omnitrophica bacterium 4484_70.1 GN=B6D56_04375 PE=4 SV=1 +---KKILFLVFTVKAKDELIDKVLEFAERIGARIIALNVVDFGMIRhlsqklekreaevsvdleeegwMYLYYVEERAKDRGI-MINIVQEEGVVERELIKASEKFAVDLVVISREEHQGIAN--FNKFIESLLLRVKCPLLIL--- +>tr|E8RAY7|E8RAY7_DESPD Uncharacterized protein OS=Desulfobulbus propionicus (strain ATCC 33891 / DSM 2032 / 1pr3) GN=Despr_1476 PE=4 SV=1 +QDRPYILVVTRNGHLSEHVMDYALNVAHRLGYGIVTVHVDTLPFYkdsgrrcrlfaaamEESTALFRGKAKTKKV-AIEHLREEGKVGVVVSRLCHaKKRIEFVIIDKGIR-----------LGEVAKHSPVPVFPV--- +>tr|F2NHG3|F2NHG3_DESAR Uncharacterized protein OS=Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2) GN=Desac_1218 PE=4 SV=1 +PHSRKILLVSDGEKFDRAATEYALNVAQRLNNDIIAMNVCPSlaPLKnrfspfrlsrqelfkrraASGFTDLQRQAAAKGV-QCWHLINFGELNQAVEELNQeVKRIEFVITGAETG-----------DEKGTEAVTLPMFLI--- +>tr|A0A1M7Y912|A0A1M7Y912_9DELT Uncharacterized protein OS=Desulfopila aestuarii DSM 18488 GN=SAMN02745220_02700 PE=4 SV=1 +GNRGCILVVTSQAHPAQHVMDYVISVADRLGSKIIMASVNPRPLLrensflsrtvrvavSPEADIFRAKAQGRGI-AYECIAESGKIDKVISRLCHiVKRVEFVVIDQGIR-----------MEEVAAGSPVPVFSV--- +>tr|A0A1J5R473|A0A1J5R473_9ZZZZ Universal stress protein family protein OS=mine drainage metagenome GN=GALL_273590 PE=4 SV=1 +--FKNILIPVNKGMDASVAVKKALELKDEKEQvRIHFLMYRNESFEYnflnffkkkkssgnssyntlfeTRFPSFKKEIEEQcdNCSLVIDTIPQKNITKGLIKYINENSIDLFLFCQKRATHGLGFSKKINFNKIARQSSCSVLSITPG +>tr|A0A0H3T1L7|A0A0H3T1L7_9GAMM Uncharacterized protein OS=Photobacterium kishitanii GN=UA38_06495 PE=4 SV=1 +-MYKKVLYALDID--SKPYLLKAIALAEQLNAELFVGYATNIDDQLfsddayfghqlgddlvntekdELENKIKDLITGTSLNKDHVYIVSGPVGMAIERLATHLSVDLVVMANSHHYFS---FLSKNGFLIKLATRHDFLSFS-- +>tr|A0A1A7USV2|A0A1A7USV2_9VIBR Universal stress protein family protein OS=Vibrio mediterranei GN=VME0621_01253 PE=4 SV=1 +-MSNPVIYALNLH--SPQSLKRAASIARRFEGPFYVCYVTDLEEELeddteyfgevdaqayvnkkhsELKAKIHAMIDKASLQCEDVYILNGPIALTINELAEKVSAQLIIVSKTHHKYL---KWADHQRDIESRSHCDVYVMN-- +>tr|A0A135I702|A0A135I702_9GAMM Uncharacterized protein OS=Enterovibrio coralii GN=ATN88_00150 PE=4 SV=1 +-MYSKILYALDIN--SKPHLEKAIEISRQLNAELYIGFATYLGESYeedevyfgkltgdqivddkknALEEKIESLISGTDINKEQIYIVDGPVGKAIDKLATSLNVELVMVAKSHHHFS---LMMKNDTLIRLTTHYDFLSFS-- +>tr|O28746|O28746_ARCFU Uncharacterized protein OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) GN=AF_1526 PE +--MERILLVLDDTGRGEIAFQKLKKLAEdGLRGEVYILYIREMEVPPfvpeekelaayhrlmtqsmKKLEGFKNQLEKAGLKVSDVSVVFGKYADRLLLVEKQIKPDLIVVGFKGGllkRVIGGFFGKDPCEVLLKKSKASLLICRG- +>tr|A0A0S2SFZ3|A0A0S2SFZ3_9GAMM Uncharacterized protein OS=Aeromonas schubertii GN=ATO46_02520 PE=4 SV=1 +-MKNGIVLLLEGKAYERETLAKASRLAHAMGSPLTLLHLTHSSQVRnehielpaaersaraelAAKAGISELVATLSHPAEYQCLAVDDVVRDLAAWLASHPCDLLLVGSRHH-----WMEGSLARQLLYKLPVDIQICHE- +>tr|X1N7A9|X1N7A9_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S06H3_24280 PE=4 SV=1 +-PVKKIVFATDLKElhNYKLYLNEVIRVAEIFDASIHFLHISNrekahPPESREVYKAIMEIIEWNKR-HVFRTCFGKDIISMVEEYIKKNEVELLAVVKHHHYFPETLFHKSFSNEVSLRSKVPVLVMREQ +>tr|A0A1W9QT36|A0A1W9QT36_9BACT Uncharacterized protein OS=Bacteroidetes bacterium 4484_249 GN=B6D61_10330 PE=4 SV=1 +QKLSNIIIALDQTDMSIGILHKAMDFCSLIDPKpaVTCLHIGHLPYYSELGEVAVEDYREFGNtdfkkisevffekqkesfenfieknlkgydnikPNIEFIGEKRvKPYHALKDYIDSGKADLLIMGTKSHSGFDNFLLGSFAEKMIMKT---------- +>tr|A0A1J5R473|A0A1J5R473_9ZZZZ Universal stress protein family protein OS=mine drainage metagenome GN=GALL_273590 PE=4 SV=1 +HSVKSIILPVG-SFIPEKKIQIAIAFAQKYNGLIHLVTMLDNSDEGhskmkvDIFYKTYKILQECGYTPQYKILSKYESHEILLRYAENANADLILLNPEKRSFLSTITVNAIVDFISPHSHLQVLMTKPN +>tr|I4C0D0|I4C0D0_DESTA Uncharacterized protein OS=Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1) GN=Desti_0279 PE=4 SV=1 +--MNGIGLCAIFSRQGDWAFDYALNLARHYKCKLNIFHFLESPYMLrrdvvfvdaektetapvtpeliaKKDKELRESFEDRlgDYVEVGFRLCEGNDEWELRKCFKKGDYEILVIGYNAKHAA---FGGTtTIEEFGAKFKGPLVLIGPD +>tr|I4CBA5|I4CBA5_DESTA Uncharacterized protein OS=Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1) GN=Desti_4209 PE=4 SV=1 +--MNGIGLCAVFSRQGDWAFDYALSLARHHKTKLNIFHFLESPYMLrrdvvfvdaekkettivnpdfiaKKDKEMREKYDDRlgDYVEVGFRLCEGNDELELRKCFKKGDYEILVIGYNEKGAS---FGGTtTIEEFCKKFKGPVILVGPE +>tr|E4NUY7|E4NUY7_HALBP Uncharacterized protein OS=Halogeometricum borinquense (strain ATCC 700274 / DSM 11551 / JCM 10706 / PR3) GN=Hbor_34550 PE=4 SV +-SLSSCLVPVARGPHLDTTLNIARVIGETHDAWIDFFHVVDNDESRSETDALFEYCTNHlgDFDEFDTWRYEGwSPAQAIVDQSS--YYDATVIAAPQKSRLREFVDGSTTEVVQSLCENTVVTVRSG +>tr|A0A1F3RTF0|A0A1F3RTF0_9PROT Uncharacterized protein OS=Bdellovibrionales bacterium GWA1_52_35 GN=A2X97_16640 PE=4 SV=1 +QPFDSIVVPMKGDPmRMDAALTYSLQIGGRARIPLDILHVSPKQLGPdssaigqlsdefyheyprrieEMIAEASPLSSVRERTIIRDFLQvRGDMTHEIFRSIKKHKSGLLVIEWDGKFARGR---SELIRAIILASHRPVLVVKP- +>tr|A0A1Q8B9W3|A0A1Q8B9W3_9BACT Uncharacterized protein OS=Acidobacteria bacterium 13_1_20CM_2_55_15 GN=AUG08_06900 PE=4 SV=1 +---ERILVGITPRSDARPILESGRRNADRFHGELFVAYVRQANLSpedEAALEENLAIARELDA-TIKVLDGQRDPARALIAFARDTGITQIFIGHSMRKGFWQRLRGNPVERLIDLAEgIDVRVFPQR +>tr|A0A1W9F1U1|A0A1W9F1U1_9GAMM Uncharacterized protein OS=Serratia nematodiphila DZ0503SBS1 GN=AK51_06495 PE=4 SV=1 +---DSILLCVGHNSGNEKLVRIAARLAARLGCHWHAVYVETPKLHrlpENqrrAILRALRLAQELAP-KPPPWPIR--PKSA-QCCATPANITSaksssaaaasnagscaaaspIASAGWARISI----W--------------------- +>tr|A0A1Y3GDF1|A0A1Y3GDF1_9EURY Nucleotide-binding protein UspA family OS=Methanonatronarchaeum thermophilum GN=AMET1_0138 PE=4 SV=1 +----KVVVPVRNPSTEFCLLKMAGAIIGGGVGELVVVNVVEVPPQIslsqsieaesrgldvqkkilDQAENLVGSLDRLGDVSLRTRAIVGrDVGSSVLRVLEEEDADHLVIGWDGEVSKKDYVLGSKIDPIVRGACCEVTVVKDG +>tr|A0A1Q6W979|A0A1Q6W979_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium 13_2_20CM_66_19 GN=AUH10_13910 PE=3 SV=1 +--PQRVLIHWMSDASRSATLAVSASVLRHVAAEAVYVSIFPEERAGEQRHGLRELLDArseaqlaHGL-EMRTELRFGDVASELARRLAEAPAQMLIVGLSDLTGFAASF------RVLLETGqWPVLIVYRA +>tr|A0A1M5IRQ2|A0A1M5IRQ2_9FLAO Universal stress protein family protein OS=Spongiibacterium flavum GN=SAMN04488116_0889 PE=4 SV=1 +---KKISVIADISANLENVIANATELAKAIKGTVEVLYVKAPTDIvkgdnqlsamrtlhrdtrdtESKLRSAVEKFSSKTGSKVTYKIAYGNTKNTIKAYLEKEQPHTVVLGKPK-SKFPGIPASGIPSFIMTACDANVLVTGDD +>tr|D3F9J2|D3F9J2_CONWI Uncharacterized protein OS=Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577) GN=Cwoe_0726 PE=4 SV=1 +PGPRRVLFPFLGRSLSKPALQAALRLARAEGATLVPVYLAEVPRHLpldcalpgqsavalALLDAIEQDARRCGV-PVDARIEKGrDSRHALREMMAHERYDRIVLAAETANGGDG-FSPDETAWLLANAPGEIVVLRPD +>tr|A0A0Q5UP24|A0A0Q5UP24_9FLAO Uncharacterized protein OS=Flavobacterium sp. Leaf359 GN=ASG38_04645 PE=4 SV=1 +--MKNLLIPSTLEKDTINAIKVAIQQSKGKSCTIYLALVSEIPDTYssaaflrniksdmsvsqkSILHSCRELVAASQNCSLKIHNQYGISAPVMKNLMEHLNIELTILTPSYKNTERR--IHNQFLQILANCKCPIL----- +>tr|A0A0N7K954|A0A0N7K954_FLAPS Uncharacterized protein OS=Flavobacterium psychrophilum GN=AMR72_12550 PE=4 SV=1 +--MKNILVPTTLQHDTLYSVKAAIKQSAGANCVITMVLLNEAPEAeSaayflrktkytnttaqsTVLENCRKAAYATDNCRLEIHNQYGLSAPLLKNLLEHLGTNLIIIPASYKKETGK--IHHHFLGLLANSRIPML----- +>tr|A0A1D9PAS8|A0A1D9PAS8_9FLAO Uncharacterized protein OS=Flavobacterium sp. PK15 GN=BIW12_09365 PE=4 SV=1 +--MKNVLIPSTLEPDTINAVKIAIQQSKGKKCTLFLVLVEEIPDSYssttflrsmksemtasqkKVLEYCRELITISQNCNLKIHYQYGISAPLMRNLIQHLEIELTILSPSYRKDERK--IHNQFVQILSNCKCPIL----- +>tr|M5TCJ1|M5TCJ1_9PLAN Uncharacterized protein OS=Rhodopirellula sp. SWK7 GN=RRSWK_06068 PE=4 SV=1 +-RPARVMLVLDGSDQDPTSIASANHLRNVCNTETLVLDARETATDDSspdanaapptpssphpPSDLATQTAGQITG-ARAISRPSGESFEAILDSLKTHDVNLLIVPCPFGRSFGKVgadSVGTVVDVLLSRCSVPFLVIRHP +>tr|M2B4S6|M2B4S6_9PLAN Uncharacterized protein OS=Rhodopirellula europaea 6C GN=RE6C_02097 PE=4 SV=1 +-RPSRVMLVLDGSPQDATSIETAKTLREEFNTETLVLDARDAAQPTDaATEDAIQAARQMSG-ARAIARGEGEAFEVILQALRTHDVNMVLVPCPFGRSFERVgtdSVGTVMDVLLSRCPVPILVTRRE +>tr|A0A1F3SGP4|A0A1F3SGP4_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium GWA2_49_15 GN=A2X86_10535 PE=4 SV=1 +-QFKKVSVLLDPTQNYDRQLGQVVKLIKRLKAKLHIICLVDVQFLglnleafpftpspleiqnktsqvllqkaELFLKELESGLKKDGI-EVEHTVHvtlNEENIYGLDKLLHEQAPNLVMISPRS-QFLGHFSLGSTTHYLMKHNNCNFYLLP-- +>tr|T0DM36|T0DM36_9PROT Uncharacterized protein OS=Bacteriovorax sp. BAL6_X GN=M902_2373 PE=4 SV=1 +-NFKRITYLIPYESLDKDDLAKVANLARCNNAKVHMDCIVPLNFVsynlevfpegpypreiianemselhkgaEDELQKAVAILKEEGV-NANYTLKmilNADPGQRLEELVKEEKTDLVVIKPQH-YIFDHLSLGSITLDIMKNTDCNLYLLH-- +>tr|A0A1D6Q6L6|A0A1D6Q6L6_MAIZE U-box domain-containing protein 33 OS=Zea mays GN=ZEAMMB73_Zm00001d051397 PE=4 SV=1 +---DRVFVAVPEDAKnGKSTLLWALENPAKDCAGVVVAHVHCpaqmipmmgakvhhstvnpqrvneyrkkvRAEVEEKLDEYVLVCRRQKVSCQKVVIEMDDAVRGLEQLITLHGVAKLVMGAAADKHYSKkmkSLKSKTALRLTEVAApsCKIWFT--- +>tr|A0A1S3V5X5|A0A1S3V5X5_VIGRR U-box domain-containing protein 33 isoform X1 OS=Vigna radiata var. radiata GN=LOC106772098 PE=4 SV=1 +---DTVYVAVGNNAEkTQQLLHWTVNNFS--GKNVCLLHIHRphslnsfscatdknlsgyepkdlpiqafqdqgNQSVHELLDQYILDLVPAGVRACKLLIEMDDIEKGITEAIAQHSIRWLVVGAAADGYNMGklaKQDSEKAIFIREQALlsCNIWFI--- +>tr|A0A1F3SGP4|A0A1F3SGP4_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium GWA2_49_15 GN=A2X86_10535 PE=4 SV=1 +--MKKFIVNTDLYESSDANVYTSYHLAKLLGLKPQLFFVDTISPMidktfhpesihtsyatdlvwqkkyeVTVLEKISQQLERLSLAkeDFDLEVFEGAISDGVKSLKRHEDIELLSVGASEHGEINRLFFNTFAEKIFFNLHKETLVVRKK +>tr|A0A1G1EVG9|A0A1G1EVG9_9BACT Uncharacterized protein OS=Nitrospirae bacterium GWB2_47_37 GN=A2X55_03945 PE=4 SV=1 +-GKKQLLFVTYHDENVEAGLSYAVDLAKTMNEDISILMLFRRKAMErledymtavafaeegefktareligedlkrrnesyeEKAGLLMKRCSDAGV-SVDVGASAADIVSAVRNLLRQNsKIDMVLLSPAVTEGGN--ISSKELNRLVKTSSRPVVTM--- +>tr|A0A1G1F872|A0A1G1F872_9BACT Uncharacterized protein OS=Nitrospirae bacterium GWC2_57_13 GN=A2X56_11390 PE=4 SV=1 +-KKRKLLFVTYGEEGLEAGFSYAVELAKALYENIALLLLRKNGVKDsfenlmsavtfaeagehetamsmlktvsqnsleRKVSELVDQCGREGV-GVSVHTSDSDAVKGIKMFLKEHsGVDKVVLSPVVTEDGQ--VSSRDLNRLVRTASRPIVTM--- +>tr|A0A1F2TNI3|A0A1F2TNI3_9BACT Uncharacterized protein OS=Acidobacteria bacterium RIFCSPLOWO2_12_FULL_66_21 GN=A3G21_12945 PE=4 SV=1 +--MREILLHGGSDEAFDRSAVFARRLAQSFGARLHVVYTVEDPLSAgwtaemgverlpeihqaieaearDRLARLIPMDEQERL-NVEIVVRTGAAGHELVRYTREASIDLAIVTAAPADDR----GVALARALLDHGRCAVLVLR-- +>tr|A0A0L8VCY8|A0A0L8VCY8_9BACT Triose-phosphate isomerase OS=Sunxiuqinia dokdonensis GN=NC99_11360 PE=4 SV=1 +--LNNYLYATAFHAEDLKAIKHLSETTAGADGKnLTIFHNMETLDFESKLKWIgFKTLVKDSVSGFHLKFEhanEKNVRDALKKYLTNESLDVIVILKEKKGFFEDLFSSSETHYVLTHFDKPVLIYHEE +>tr|A0A176WKN5|A0A176WKN5_MARPO Uncharacterized protein OS=Marchantia polymorpha subsp. ruderalis GN=AXG93_4773s1670 PE=4 SV=1 +QSPETIVVGVSLGQESQDLLAWACNTAAQSGDHIIALHVIDHSAIIakelqdgglekykssvafgltSLLDPLKELCTEKEL-TTQVRVVCGeTLDKVLVEEAAALGATLLVLSTSGR-RVAPWRIQGTASYCSRHAApgCSVVVVSNK +>tr|U5VIX3|U5VIX3_9PSED Universal stress protein, UspA family OS=Pseudomonas sp. VLB120 GN=PVLB_14405 PE=4 SV=1 +MKINHLLLIAPCDDRYSPAVEQSAELAMALDASVSLAALRAPSLGgqkpsvESYLKQRASHLASRGLRVSPDVTVLKPTANGVAAQVTRCGADLVVMDHAADEAAHQANLDL---QLLEKAPCPVLFAREQ +>tr|A0A1M6HEE7|A0A1M6HEE7_9BACT Uncharacterized hydrophobic domain-containing protein OS=Rubritalea squalenifaciens DSM 18772 GN=SAMN02745181_1452 PE=4 SV=1 +---GKVLLPCAGGPHSRRGLKIAADS---VGMDVTAFFVEPDVDDvsrAVGGVHLERYVKRAGVDPMSVERKvslNSDVYGAIRKEVETGEYGLMLIGASGASSIRRKLFGTVPDRLLRG----------- +>tr|B9WHV3|B9WHV3_CANDC Uncharacterized protein OS=Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841) GN=Cd36_5370 +-MFRTILVYISGRIHTWVALDWILSKFIEDGDHIIIIASIDPCLLNtkdykdrsrrstsrtrmslspakigsqsslirgntlspqrsrtdesqpfqptsdiydpfirlkeksrpenivkianNLMDYIMKVINPKIITRITVELVEGDTKGVLQDMYRLYEPSLVCTGAKPNarvgAPLRSWQSSKLTDRLIKNFPLPVIAVPA- +>tr|A0A0A6KCP8|A0A0A6KCP8_CANAX Uncharacterized protein OS=Candida albicans P75010 GN=MGE_04316 PE=4 SV=1 +-MFRTILVYVSGRIHTWVALDWILSKFIEDGDHVIIIASINPCLLSgsnkdrsrratsrtrmslspakigsqssvirgntlspqrsrtdepqstrqdsidpfirlkeksrpenivkiahNLMDYVMKVINPKIIARITVELVEGDTKEVLQDMYRLYEPNLVCTGAKPNarmgAPLRSWQSSKLTDRLIKNFPLPVIAVPA- +>tr|M3JYF5|M3JYF5_CANMX Uncharacterized protein (Fragment) OS=Candida maltosa (strain Xu316) GN=G210_1498 PE=4 SV=1 +-MFRDIIVYISGRIHTWVALDWILSKFIENGDHVIIVAAVSPKLVDdkgrtgrsgtispqrgrtlsprrgastfspardedpvsrlldrsrpenicqigaNIMDYSLKIINPNIIAKITVEVVVGRTKDVLQDMYRLYEPNLVCTGSKPNmrlgAPLRSWQSSKITDRLVKNFPLPLIAVPA- +>tr|A0A183B1T5|A0A183B1T5_9TREM Uncharacterized protein OS=Echinostoma caproni PE=4 SV=1 +--PTTIIIPIDRNHPTLRTLELYYRTISSENYRIIFVHVIQPGNTNslfgirasmvssvtgnpvpikkKVLVEAKLLCREhvqhaqsHGLKAKSVIYVNSHVGPALIQAAARYRAD----------LF-------------------------- +>tr|R4M6T0|R4M6T0_MYCTX Sensor protein OS=Mycobacterium tuberculosis CAS/NITR204 GN=J113_07245 PE=4 SV=1 +---ERVVVAVTGGPESETLVRRASRIASKSSAELMVVHVIRGDGLAgvsapqLGRPR--LDKPRCDQ-PAlvLRRHAAGLRPRDERHAARRRHIAAIAMGTP------------------------------- +>tr|A0A1F9H889|A0A1F9H889_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFCSPLOWO2_02_FULL_40_36 GN=A3I69_09695 PE=4 SV=1 +-KEKVVVLAVSKERKSQEAMHWAFHHAKETHKKVRAVYVVHQDESdgKKYLEDFEKQARTFQV-GYDSRLMMGDYLKACEDLSKEGESAVIVFLEKQKGFFKKLFEGSELDGLRMRFVCEMKVYR-- +>tr|A0A1V2M220|A0A1V2M220_9FIRM Uncharacterized protein OS=Epulopiscium sp. SCG-B11WGA-EpuloA1 GN=AN396_00600 PE=4 SV=1 +---KTILFSIS-NTIDMEALLYAQNEAIKEDAKLIVLYITSPLTFSscytypsvlysvanlniDNIEVAHEALSQKissilEDCPHQVICLIGPQIDSILNVAKEYNVEKIILPYES-SIIDKLSNKSMKLKLAKKCDIPIDIFGS- +>tr|E3H640|E3H640_ILYPC Uncharacterized protein OS=Ilyobacter polytropus (strain DSM 2926 / CuHBu1) GN=Ilyop_0009 PE=4 SV=1 +-MLRKVVILFGNELNTENLLKTGKALKEKYNCEIKGLYVRDLRKHEiippsveglvvdpssryiveewekfesEQITILKDKFKSYFD-ENNLIVKDGVTPDTALEELK--GFDLLVLGKGER-------ISPDLKFILKNHYKPIIIVS-- +>tr|A0A0R1HUR8|A0A0R1HUR8_9LACO Uncharacterized protein OS=Lactobacillus kimchicus JCM 15530 GN=FC96_GL002467 PE=4 SV=1 +---KQIVVGVDGGHQAKGALDNAVKLSRAGQIPITLVQVVDPELTkhvanpqsylkhltETVEQELKALCEQLPADiKHSYQMTIGDPVNTLISYLKE-STNYLLVAQSNGGGYNIQKIGHVAKALMSNGHRNL------ +>tr|A0A1L8TP69|A0A1L8TP69_9ENTE Uncharacterized protein OS=Enterococcus hermanniensis GN=RV04_GL001236 PE=4 SV=1 +-MSTKILVLVGSDGKPENAFRKAVELAEKEKSELHVLIYNTTLKENialeeseefsledgymgeltmpdiqlmedldeenqAEIKEFVSSINLSNPDNLIVSYVSYGLKKAVLNYANEKAIDLVILGQEE-TLYTRLTFDSLIKHVANKSASNLLIIK-- +>tr|A0A1E7H405|A0A1E7H405_9DELT Uncharacterized protein OS=Desulfobulbaceae bacterium S3730MH12 GN=BA862_01005 PE=4 SV=1 +-----------DSAKSDTMVAELKKQALVCSADVTLLHVVEEESDShvrrygiavegeklmARLEETVQLFRRYGI-DPTIRLVRGEVVAVLAELCTELDAELLVLGSSR-KKEGILRSASVRRRLEKNCPCPLTV---- +>tr|A0A1G9NBS3|A0A1G9NBS3_9SPHI Nucleotide-binding universal stress protein, UspA family OS=Pedobacter steynii GN=SAMN05421820_102272 PE=4 SV=1 +--MKTILVLTDFSKNALIAAEEAALLAGRLNANLLLVYTDYGIPVStfypgifhgggdhswelhceremnkikNHLSRLFSLIDSNQCRpIISSRVSQGDLTGQVVNLLKDGNIALMAIGAATGIKTYPILSETEVYSMIETVGCRVLTFPEN +>tr|A8UV70|A8UV70_9AQUI Uncharacterized protein OS=Hydrogenivirga sp. 128-5-R1-1 GN=HG1285_16011 PE=4 SV=1 +--MRIVLILSDSSSECKKALETLDRYGEAFSADIGVFVILEDLYRlesasvslgvplppdtvksakertENKIKTLWRHIKKDEKAHIDIKAVAGELGEEVVKFVGEEKPDMILWGCQPTPVLCR---------VIDEINVPSLIIK-- +>tr|A0A1X7DKY1|A0A1X7DKY1_9PSED Universal stress protein family protein OS=Pseudomonas sp. URMO17WK12:I5 GN=SAMN02745903_01863 PE=4 SV=1 +---------LDDGDANAAVVEATRLITHARKAKMHLFCVYDQAALlrhsehyslaeipsyESLASAFKRFVAQLGIPDAYHQLIVGSCAHTLCAYANRCGYDTVVITSPHRAWQFA-----TLEYLLSSLKCSLLVVP-- +>tr|I3UFD2|I3UFD2_ADVKW Osmosensitive K+ channel histidine kinase kdpD OS=Advenella kashmirensis (strain DSM 17095 / LMG 22695 / WT001) GN=TKWG_19630 P +---EGILVVVDTALTpnaAQALIRHGSRLSGQMSCPMHVMFLREAANSRGPARSngdwqLLLQQAEQLQATTTEHYCNGDVMPDIVAYCRSQNLSRLLLDRSVLRRYWWRL--SPLVRVGQLGPdIDVIIYGG- +>tr|T4NTG6|T4NTG6_CLODI Universal stress family protein OS=Clostridioides difficile P28 GN=QSI_1894 PE=4 SV=1 +---EHILLCLSPSRSNALVIRTAARMASAFFAEFTALYVE-NVNEEPLCREDLEQLEQNRRlaqhfHANIVSVAGENIAQQISEYAKISGVSKIVIGRSSPRPHS--RARTLIDQLTLLAPdLEIYIIPD- +>tr|R4KCJ4|R4KCJ4_9FIRM Universal stress family protein OS=Desulfotomaculum gibsoniae DSM 7213 GN=Desgi_1404 PE=4 SV=1 +--MTRMLLAVNGAQYSTGAIKKAIWLSKLEDAQLDVLYVNPPCNQMypdipqlcfwmpdfeykmvtqrlrnkVLDGEIIPIFKEAGL-DPRVVVTSRDQDEKIKEMSTENHYDKIFIASPSR----------------------------- +>tr|A0A0F2PD24|A0A0F2PD24_9FIRM Uncharacterized protein OS=Peptococcaceae bacterium BRH_c8a GN=VR67_14490 PE=4 SV=1 +--MAKMLLVVNGADYSMEAVRKAVWLAKKDGAQVEVLYVNPTCVQLypnvpglcfwmpefeykirarqlmerVLNEDIKPILDEAQL-DIQMLTTEHDQDTEIKRLSEVNSYDKIFITGHSK----------------------------- +>tr|A0A1S2Y2I8|A0A1S2Y2I8_CICAR probable receptor-like serine/threonine-protein kinase At5g57670 OS=Cicer arietinum GN=LOC101490391 PE=4 SV=1 +-GARTVVVAVKMESHthSIQLLTWSLVNVARPGDLLLALHVLRNdeivnRDGksslfslvkafDSVLSAYEGFCNLKQV-DLKLKICRGsSVRRILVREANEYCASHVIVGKPQGlSKIRP--SISIARYCAKKLSkdCCVLAVDNG +>tr|A0A1S3B0F0|A0A1S3B0F0_CUCME LRR receptor-like serine/threonine-protein kinase GSO1 isoform X1 OS=Cucumis melo GN=LOC103484690 PE=4 SV=1 +-KGQPTFSGIIVDGGGARWLDGGDVQSAKWRHHLVAIHICEDldDG----LKFSESFP-VMKT-NEIRGSDSGeTFAKKLMKRLAKQRGMAVMLEFDPFGPLGN--LVSLAKCYFNQLPatSIVLAVHKG +>tr|A0A1Y1WLQ2|A0A1Y1WLQ2_9FUNG Uncharacterized protein OS=Linderina pennispora GN=DL89DRAFT_264304 PE=4 SV=1 +NRPYTIVVRIDDSREGYAAAEYACSLCLKLKVKYRLIFLYVVALYKrsnlnlinrqteqlnaeirenaedsmmkckQFLSRFESLLSFEWI-SIKDEGNVGPIAAKFIKKELQTVVDLVVVGRSADTALKTIVGGHVSDYFMKTLEVPLMVVKDE +>tr|A0A1R4IMD4|A0A1R4IMD4_9SPHI Uncharacterized protein OS=Sphingobacterium sp. JB170 GN=FM107_02595 PE=4 SV=1 +--MKAIIITTDFSESSLNAAKYAAAaeqitrstpvseirfWLERLTTKLLVLNVAGEGKRfdrdiTPKQYKMQDLLDGFYLE--NRYTENHNIADEIEDVAEDHHAGLIITIPKSYRFFEELFHRGVSKRLIRKLDIPSLLL--- +>tr|A0A0L8VCY8|A0A0L8VCY8_9BACT Triose-phosphate isomerase OS=Sunxiuqinia dokdonensis GN=NC99_11360 PE=4 SV=1 +------MLLLDTRKNMENLICSAFSLSNQLKRKLKIVYVLDIHWVGtgvtggelggptvpgisetymvveksirkdfeqaesEMRKTVAKYFEKYPQNvHYEIEVAEANRLDVVSKTVKR-EEDVLLLMSNYNTYSGLSTGTINYPNIIDKVPCPVLIIPDR +>tr|A0A0L0HL67|A0A0L0HL67_SPIPN Uncharacterized protein OS=Spizellomyces punctatus DAOM BR117 GN=SPPG_03425 PE=4 SV=1 +---RKLMVAVDAADQeGLRTLDWACKEMVQPGDTLVVVRVVKEQKGFkggyaaasemmksiesraheeadritCHALRALGQQSKKCI-DLYVKYRTGDPRSQIRELVGTEHPDVLIVGNNRKRVSNTFFHGGEQSFLPEGSNVPVV----- +>tr|A0A183C9W3|A0A183C9W3_GLOPA Uncharacterized protein OS=Globodera pallida PE=4 SV=1 +---RRVLVAIDGGGQSEYLVRVGRRIAERRDAPWTVVTVQRRREDDSTRREIDAAFALARRLGGEAELLHGpSIADALLDHAAHNSVSTLVLGRTRERPFARMLNRTLTQQLIQR----------- +>tr|K9YCQ0|K9YCQ0_HALP7 Uncharacterized protein OS=Halothece sp. (strain PCC 7418) GN=PCC7418_2568 PE=4 SV=1 +--MLKILLYVDVNQLdyNLNFLNRAIAYASALNGKFLLMTVLPDYDSYflspllpdqfkekadakvrEALEEFVARYLPEAL-MENIILRYGLVHTQILAVAEEEKVDLIFLNCDR-AEPVDYLLGTIEGRVNRRAPCDIVFFHR- +>tr|A0A1F9ELP3|A0A1F9ELP3_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RBG_19FT_COMBO_46_12 GN=A2026_22455 PE=4 SV=1 +MTISKILIAVSATKDAPVLILDVFQIIEKNKASVKVLFISYLSDLFkkslgpntlhhwmkeekECIEKVISYFARMDI-PYHSKVIIVPPWEIIFYEMSEEGSDLIILQSELLERWkKDKANCALCSDVLSKSRCPILVIHST +>tr|F6DDM1|F6DDM1_THETG TrkA-C domain protein OS=Thermus thermophilus (strain SG0.5JP17-16) GN=Ththe16_0342 PE=4 SV=1 +HPYRSILVSAN-TEALSPLLASAMDLARIFGSEVYVLFVSRVEAFMppeekellENLKLLVERARKTSGLEVHLIRKEGNPVRETLKLLK-GKFNLLALGYTP-GRRTAFFRPYVPQLLAQASPVSTLLVPE- +>tr|A0A1V4Y793|A0A1V4Y793_9DELT Universal stress protein family protein OS=Syntrophus sp. PtaB.Bin075 GN=A4E74_01336 PE=4 SV=1 +-------LIYNGCSEGDHSLDLAVSLSRQASWPLTILLPSEDPFRidslNRQLEDYFDQLTGEPLIDWDTVVLSGQQGEAAFRFLLDGSIELLVMSRPD--------LDSSMVMLLNKSPIPVIVTR-- +>tr|A0A0F2N781|A0A0F2N781_9FIRM Uncharacterized protein OS=Peptococcaceae bacterium BRH_c4a GN=VR68_15735 PE=4 SV=1 +-MFKSILLVIGEDSGNSEIIPAAVNLAAVYGASLTAVFIAGHDYECmlgdewisdsgmlnrffsymesemnrrtvHVLDEVTEKCNNLGL-QVTVMQKTGNPGSAVISLYEEMGPFDLVVINKSLINRGDNRVKKGMDSVIRSLVCPMLIYPEQ +>tr|A0A1Q9N892|A0A1Q9N892_9ARCH Uncharacterized protein OS=Candidatus Odinarchaeota archaeon LCB_4 GN=OdinLCB4_15270 PE=4 SV=1 +----KVLLPVSVKVNRELLLRSFEILKGLKNLDLIVFHVLELPMTAsldisehnqkvqelnQQLEPTIKWIEEQSFKIKSKIVVARHVSEAIVEEANSGNYDLVVLLKREPpKGVRRLFYRSHTDYVTGKLNCAALIL--- +>tr|T0Y1I1|T0Y1I1_9ZZZZ Universal stress protein UspE (Fragment) OS=mine drainage metagenome GN=B1A_22114 PE=4 SV=1 +----RIAAAVDVSEEeteglAASIVRIARRLALATGGELDLIYAEHLSAEhaesRTHAGRLRNLARQADLDEHHAYILAGPPERELAAFAAGRDYDVLALGALTHRKVAVQLVGNLTATLVEALDSDFLLIKPD +>tr|A0A1F8PCV4|A0A1F8PCV4_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_48_8 GN=A2Z14_01725 PE=4 SV=1 +-PIEKILLILRCENRDHIAVDWVVKMGLPSKAVVTMSVPLPPIPRmyqglsgmsvqipkmlkgnsalEKHLQSLTARLASHGI-EVKLNILEGDTKRIIQQEVMEGEYDLVSVAAKPESWLKRTLLSSVVNPVLEYARIPIFIAKP- +>tr|T0MWF5|T0MWF5_9EURY Uncharacterized protein OS=Thermoplasmatales archaeon I-plasma GN=AMDU3_IPLC00002G0307 PE=4 SV=1 +--MKDVMVAIDSPEYLERALREVVYLFPEAE-RFDLVYLMPVNYShfwvpdqqkresskRKIEEKIREVFSSNRSIaaKFRIEIIENDPDRELMELSRRENVDAIVIERWSHWKGGHSITKRVAIKTISNSGIPVTILN-- +>tr|A0A0S8B7V2|A0A0S8B7V2_9CHLR Uncharacterized protein OS=Anaerolineae bacterium SG8_19 GN=AMJ56_12960 PE=4 SV=1 +-AFGRDLVKGTGGRVRALG----IIRGRA---------------SDeakskayesvr----TNVARLEDATG--IEIEIVEVvSAQEDLYQAFG--QYDLMILGASEEGFLRPTTFTGFPADTVAGAEHAGMVIKK- +>tr|F4KNS9|F4KNS9_PORAD Sodium/hydrogen exchanger OS=Porphyromonas asaccharolytica (strain ATCC 25260 / DSM 20707 / BCRC 10618 / JCM 6326 / LMG 13178 / +----QVLISFGRAETGVTLLEFFHRLCGGTspQVACTLMHVTTDTDIstidadhyyASSFAAPMEMAKQLDLSVERKYEIAESVPEAVLSHANHIQSNLLLLGASV-NLSQDKKDRDlvaysdkltrrwkvvtgrrrqakkeqsshsfeeIIATFAHEAPCSV------ +>tr|A0A0U2XUN4|A0A0U2XUN4_9FLAO Transporter OS=Myroides odoratimimus GN=AS202_13570 PE=4 SV=1 +----QVSLFFEDKTSLAPLMRLASSFVGKNnaDTGITAMHLVDSIEVnaftsteyeNEIFEAVQEEATALDQEVQTYYKVSNDIESDVVNVVNEQISDLLLIEVGY-SIYRGSLLGNilgfttriinpdvllnkvtgkekffenswfnaRTQQILNRSKVPV------ +>tr|K1HXH2|K1HXH2_MYROD Uncharacterized protein OS=Myroides odoratus CIP 103059 GN=HMPREF9716_01196 PE=4 SV=1 +----QVFLFFENKLSLAPLMKLANAFTGKSsvDTRITAMHMIDSQELnsfntqdyeEEIFEAVQEQATEMDQEVQTYYKVSNDIESDVVGMVHQETCDLLLIEMGY-SIYRGSVLGNilgfttriinpdvllnkvtgreklfenswfnaRTQQIMNRTKVPL------ +>tr|R5GGA1|R5GGA1_9PORP Sodium/hydrogen antiporter OS=Porphyromonas sp. CAG:1061 GN=BN460_00182 PE=4 SV=1 +----HILFSFARSKMGLTMLHIVESLFAKPeeSVELVGLHLTVGSDTsksdaelyrSQNFAPIQSHADASGYGVEEYYEVTDDPLHSIAKATRVKGADLLLVGAGL-ELSANPEDKAmrerhlkfgrsfskifsqtinffnlhnlfedHTEDFVRIPHCAI------ +>tr|A0A0G0U8M5|A0A0G0U8M5_9BACT Uncharacterized protein OS=Candidatus Uhrbacteria bacterium GW2011_GWF2_40_263 GN=UT94_C0056G0006 PE=4 SV=1 +RGEGPLMIPFGVGPTALQVLSSCLPLIKIFGQPVLFYHTTWEKKGmsssqprdhmcraaYDVLAQLCAKAHAEGIAYGEYIEKVSFVESGIVRAALEQGVSLLIMGRAKDVG-----RGSYVDQVLERSPIPVLVM--- +>tr|M7N716|M7N716_9BACT Uncharacterized protein OS=Cesiribacter andamanensis AMV16 GN=ADICEAN_00437 PE=4 SV=1 +MRCKKILIGFGSTIYSELEVDFTIRYLAQPKMLLVGAVLNDLQGLPqhepcedskckgsaqacvqkkvgkdrqRLHAYLHERCEALCC-RAVVHQDGGTTLDALMHETR--YADLLVISQETYLASTtSGGQLVPVSRVLENCDCPVLVVPPH +>tr|A0A0D3LJZ7|A0A0D3LJZ7_9BACT Uncharacterized protein OS=Flammeovirgaceae bacterium 311 GN=D770_20760 PE=4 SV=1 +MRCKKIIIGFGSSEFSELEIDFTLRYLAQPKMLVVGTVITDLLVPNghtacseggctgegqscvhkntqrdrtRLYHYLQEQCKDLGA-KSVIHQESGSTLEVLMHQTR--YADLLVLSQETYLASVAGPLPLPVSKMLETCSCPVFVLPAK +>tr|E3H640|E3H640_ILYPC Uncharacterized protein OS=Ilyobacter polytropus (strain DSM 2926 / CuHBu1) GN=Ilyop_0009 PE=4 SV=1 +-KFDKVMIANDKSFKINKSFFRFMSIFEDIkEFDSYSVGLEDEE-----DNSFSEYLQGSDK-VIRTKECQGDELEVLIEEAK--EHNLLIMGNLTHSYLVEKITGHIGVKLIESLKIPIFIA--- +>tr|A0A0X8JUM2|A0A0X8JUM2_9FUSO GntR family transcriptional regulator OS=Leptotrichia sp. oral taxon 847 GN=AXF11_05505 PE=4 SV=1 +-ELENILLLDDGAYNANKTLFTFLYMFGEQKINVLRVNSD--I-----EKEEDGLVQRFGK-NYNLIYKKGETFKTLLQETK--NYDFILMGDLRYTIMVEKITGKLGIRLLENVKKPIFIV--- +>tr|A0A1C6FQB5|A0A1C6FQB5_9FIRM Uncharacterized protein OS=uncultured Ruminococcus sp. GN=SAMEA3545392_02234 PE=4 SV=1 +KATESILVCVNHPDFSKELIAYGKRLSLEMNLPLQVVNIQPSANGYcargHEIELFYQQCKEAGAE--LTILFDDDFAGATAKFARKTGAKQVVTQLFSsesGG---------------------------- +>tr|A0A1M5KI47|A0A1M5KI47_9BACT Universal stress protein family protein OS=Aliifodinibius roseus GN=SAMN05443144_13219 PE=4 SV=1 +----TVLVPIHKAELFKTLLPSAIEAAKKYNGKVLLLNVIKKPYLAspqkaeekrpkrtSFLSEGMSMLHQAECKREIQIEISPDISRTIKRIAQMRAVHLIVMGSNGN---QRAIFKNEIPYNLQQLACSIMVARGT +>tr|X1PQS7|X1PQS7_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S06H3_45391 PE=4 SV=1 +SDISTVLYATDYQETDPFHINRLIELLHPFSEVIRCVHVTTGSKAENkplNLEKLKNFFDSHSPAiQISFHEWKGeNVRKGLLEFAGVYEVDLMTMLLQKRNFLENLTHFSKSRNVVHDSKIPIIIMHEH +>tr|Q3A854|Q3A854_PELCD TrkA domain protein OS=Pelobacter carbinolicus (strain DSM 2380 / NBRC 103641 / GraBd1) GN=Pcar_0177 PE=4 SV=1 +-PYQRMALPCMAEGQLQASMQTALEIAAPLHFNLEALVCKPSEYIasndelsgCERICKTIDRLRHIYRTEIHETLVEGNPIAVFSEALQEHKLLVANIGEWRQPRlWPDWLDPDVPWHVVDRANISTLLLPAD +>tr|A0A0B5FLX5|A0A0B5FLX5_9DELT Uncharacterized protein OS=Geoalkalibacter subterraneus GN=GSUB_02365 PE=4 SV=1 +-PWEKVAVPCTDPENVQHVLETALEMSSAIKYEIEALLVRPSDYIatdeeqdaFTVMKKTVSDLSYIYKATIHATELSGNPIRSFCDHAKDYSLVVSDLTAWSDRGfIRSLFNPDVAWNIVRKTPVSVMVVPPP +>tr|Q1YZ12|Q1YZ12_9GAMM Uncharacterized protein OS=Photobacterium profundum 3TCK GN=P3TCK_07801 PE=4 SV=1 +-KNKTIIVAADiHNDSSFKLISEACDMADQWDADLHLAYSIDMPAAFtdptvyaywpqlqgalkelpysEFEHDKSFIIDTFPFEANHIHIMTGDVALRVAELAKSIDASLIVTGKSHHKF---HITHNHAKQILQAVDTDILFLK-- +>tr|D3FFI9|D3FFI9_CONWI Uncharacterized protein OS=Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577) GN=Cwoe_5377 PE=4 SV=1 +PEPARILLVANRTAATDGLRDAVRARAARGPVRFHLVVPAHPHGLhkvvdpqegdhgeaQQRLEQALPQLSaAAGA-PVTGHVGDAEPLMAIEDALNQAHYDEIVISTLP-RRISRWLHLDLVSKAR-GSGLPVTHV--- +>tr|A0A239DA77|A0A239DA77_9ACTN Uncharacterized protein OS=Geodermatophilus pulveris GN=SAMN06893096_10362 PE=4 SV=1 +TDERRVLVLANQTLCGDRLVEVVTERVAAGPHAFHVVVPATPVREqegppgtgdddvltapvrayalaQQRLDRAVEQIRAAGA-SASGEVGDADPLVAAELALEHFPADEVLVLTLP-QRFSRWLRGGLPSRVGRASGLPVQHV--- +>tr|A0A085FS36|A0A085FS36_9BURK Universal stress family protein OS=Massilia sp. LC238 GN=FG94_01145 PE=4 SV=1 +--YRRALVLVDPAVSITETLAHLGGVA--PGAEIVLLAALERKGENrlrasgagedrieaSVQQQREDALQGMGAPDGVVRIVEHGYAPTVLQYAErRLQPDLLVLPNERTARLRRLFLRSLVGEALARSDCDILALPAG +>tr|A0A109CWN2|A0A109CWN2_9BACT Uncharacterized protein OS=Nitrospirae bacterium HCH-1 GN=ASN18_0146 PE=4 SV=1 +-SKGKVTVIVYPGFTYKESITYGSDAAKMLDSVLNIKAVVPEFGISertalsmyefgvhgkiqaqaereaeAFFDSVKGFCKTSAI-EAVFDKGIGAIDDVIEEIKAEaHGINTiIVVPMPTNNMTHIAYNDEndyriEKTNNNPLKSCNVVLV--- +>tr|A0A1R1YKG7|A0A1R1YKG7_9FUNG Uncharacterized protein OS=Smittium culicis GN=AYI69_g3165 PE=4 SV=1 +------------------AAWTALNICHKDNDHIFLTCCIKEDKIfdpavvseiinnifsdeevkidkksivEAHFEKIKDMLVAKGI-SASVDIHVGNDSTATD-IIHAHRANLVVAQPAEMSALGKTFSLDWAETLSRSSICPITIVRGN +>tr|A0A1G2D0X6|A0A1G2D0X6_9BACT Uncharacterized protein OS=Candidatus Lloydbacteria bacterium RIFCSPHIGHO2_02_FULL_50_13 GN=A3D65_05230 PE=4 SV=1 +-----ILVPLGDGDSSIVAAARGIALAQTLGTEVIFWHTTWKNVHEksadprkhvyptaeAILSEAEQMGRAANVTREACRVEcAETVVESIIRVALRSGTSLVVMPRGKRKK-----YGAYADRVRaRNCPVPLLILARE +>tr|A0A1V6CQY0|A0A1V6CQY0_9BACT PTS system mannose-specific EIIBCA component OS=Planctomycetes bacterium ADurb.Bin126 GN=manP_2 PE=4 SV=1 +RMVRRVLVPAGGGAHALEGIRIADVLAKAWSLDRQVLRIIHPGPEfwerradlkrrcRHIRNATLLYLDVAEVEMPVKVRLGGDVADEIICHSR--LGDLIVIGGSSQWLMENHASASIPSRVASGVSGPVLMV--- +>tr|B8CYW6|B8CYW6_HALOH Uncharacterized protein OS=Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) GN=Hore_17360 PE=4 SV=1 +--VTKIMLILFSMAQMSKSIDYSLKLASENEASLDVKFIIEEKIPRtlsslvmytgflgekmgediektlleeyynrarKVLTEIKKRAKESDI-DYDTEIVKNGSLTYCYQEIKNNNIDYLIINYTRDRFISEQVLDYYLEDFLSDLEIPYELFYDG +>tr|A0A1W9P5Y0|A0A1W9P5Y0_9BACT Uncharacterized protein OS=Candidatus Cloacimonas sp. 4484_209 GN=B5M53_06570 PE=4 SV=1 +--MKKLMLVLSNISFSASSVNYAIERAEKEEFELVAVFVLDEEIPEsvssllmyigflgpkptddlkatllseykkraaSELEHVEKLAGEKNI-PMKKVLRKGKFVDEVLKVQEEEKADLVVTSKSRSPMLSQILSSYNLDELKNRLNEKLVVIEE- +>tr|A0A151CE28|A0A151CE28_9PROT Uncharacterized protein OS=Sulfurovum riftiae GN=AS592_03335 PE=4 SV=1 +EKIEKVLVVIQETDKIESLLRQAIRLCEGHAAVMEILYIHQSPLFElpdyfkrsetegldseRVEKEIETTLERLGNTsSYAIFIKESETVDQVLALDKGEGQTCIISFYHEE----------ITPVLARKVSSPLLVMKSE +>tr|A0A1W1CKN1|A0A1W1CKN1_9ZZZZ Uncharacterized protein OS=hydrothermal vent metagenome GN=MNB_SV-14-730 PE=4 SV=1 +HIFKRMVVVANDIENIDTLLEKAVACSKQHQTTLEVLFVHEEPLFKlpdyflsdekiskskidknKIKKSIQEKLTALNYNkTVSILVLVDDTLDQVLEYGKENKDILFITAYHKE----------LNRKLLQKSPYSFWIVKNK +>tr|A0A0S8B7V2|A0A0S8B7V2_9CHLR Uncharacterized protein OS=Anaerolineae bacterium SG8_19 GN=AMJ56_12960 PE=4 SV=1 +----LVYVPDVERARPLITAG--ALLARSRKVPMLVLQVIETAGAsipvgkqpdtqhAlSLQDQLLENNRLDDIHIIPLVRLAPTVRQGIMATIWDEQVATALVSWPADEDEGKGLSIEEVMRLVRRAPCEVVVLRDK +>tr|A0A1F2R8G3|A0A1F2R8G3_9BACT Uncharacterized protein OS=Acidobacteria bacterium RBG_16_68_9 GN=A3J75_00495 PE=4 SV=1 +-----MLLLTPPNRDPQAAAREAIAMAKSRGGELVIAVVLDPEVIErlstrldevglmgervsdtvrntlareyrsradTLAAHIVEEAQREGV-LSEVVIEEGDPSAICSRLVRKHQITLAILVAERRSWLTRLLSGSAAR---------------- +>tr|B1L589|B1L589_KORCO Nucleotide-binding protein, UspA family OS=Korarchaeum cryptofilum (strain OPF8) GN=Kcr_0872 PE=4 SV=1 +-NPRRILFPVVEDFSPDKLRALISGTIGISNAEITLLHVVRVPmtapldeetfsgelaEWEGKLRRLAEQLEGGGLRARVRVVLSRSILTGIEECLQGHDMLLLVRGTFG-GTFRKVIARISIEKLSEKYRTPIIVISRN +>tr|A0A1U8J2A8|A0A1U8J2A8_GOSHI U-box domain-containing protein 35-like OS=Gossypium hirsutum GN=LOC107902882 PE=4 SV=1 +KRNESVAVAIDKDKGRQHALKWAVAHLISRGQSITLLHVKTKPSSIptpsgshvkmsdvndevakaykqqlesqakEVFLPFRCFCSRKDIKCNEVILEDTDISKALIDYVSSFPVETLVLGAPSRSGFvRRFRTAEVTTNVSKGAPdyCTIYVIGKG +>tr|A0A101IMX2|A0A101IMX2_9CHLR ABC transporter related OS=Anaerolinaceae bacterium 46_22 GN=XE06_0165 PE=3 SV=1 +PRLGKALICLESGEPGKDNVAFAGRLLRHLGADATLMTVITNEAQddsqqrriERFLTAGKNSLARFGV-DANIQIRTGPLISAIQEEMKTEAYDLLVLGAPLPNAYGKVDLHGTIGTILNSVEnCSFLIIRS- +>tr|A0A1L9C4Z8|A0A1L9C4Z8_9EURY Uncharacterized protein OS=Methanohalophilus portucalensis FDF-1 GN=MPF_0351 PE=4 SV=1 +--INTVLVAFSATSIHRNLAKAALDMAEEKDARLIILNVRDKNMAEkvarvtkdqgfmgrgvveklaadikrdrdeliaQRLGMVEEEAGKRGI-EFETVKVKGDFVKQVIETAGMYGADVVMVASSSV----------VN-DIEKKIDAEVYSF--- +>tr|I0I708|I0I708_CALAS Uncharacterized protein OS=Caldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1) GN=CLDAP_30060 PE=4 SV=1 +PRLKHILVVLRGHGADMQALSWAAAIARAESTGVALLVLNEMGGCDlhalldpettigRHLAAVTRLATAKGI-EPSLRIRQGAPLRQIVDEAATQRYDMVVLCAESQGEFAATVLRELA----------------- +>tr|A0A0C2VNM3|A0A0C2VNM3_9PROT Uncharacterized protein OS=Sulfurovum sp. FS06-10 GN=KU29_08070 PE=4 SV=1 +EHYENIVLPIDLKEHSRTCIEATQHIF--PNSKLSLVYDYRYILDvlalredylnvvplttgvdmefneelkAQQKETFDAYVTEFNA-TGYFMEGEGLLDEDLIAYIQKEGFDLTVLYHNDEELF---FSPTLILDLLEELSTDFLMWS-- +>tr|A0A1W1BTJ7|A0A1W1BTJ7_9ZZZZ Uncharacterized protein OS=hydrothermal vent metagenome GN=MNB_SV-3-841 PE=4 SV=1 +KNYQKMALIVDVGTPSLSCIERAKSCF--PKIDIELFYDYRYIVDpsmeadlqniqiieEAQREGFKKLKEESGL-DGKFFIDGDFLGKQISDYLQEKNFDIIYACSHEDGFF---VSDNLSNTILKDLSYDMLIVN-- +>tr|A0A1J5DZ02|A0A1J5DZ02_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium CG2_30_66_27 GN=AUK27_02155 PE=4 SV=1 +RPVRTIVAGCGGGSRSERVVGAMARLSLWKSSPRGILLAVDDDPEggRERIATPRRILADAGYPVWEEKILPGPRAETVLSFCESVDADVVVLGGWGEHRWDDLLGLSVTGRMLADGQRHLFLY--- +>tr|A0A1Q6DRV2|A0A1Q6DRV2_9EURY Nucleotide-binding protein UspA family OS=Candidatus Methanohalarchaeum thermophilum GN=BTN85_1755 PE=4 SV=1 +-KIGKVAAFIKKEKDSntLETLKRANQFQTESqESKLNIIHINGKNNSkNKTRERLKEKIEEANISREDYKLRiynRENIVESIINESK--NFDTVCLGSTQLSRFKKPTFGSIPKKIALNSNENVVIIK-- +>tr|A0A087GUI4|A0A087GUI4_ARAAL Uncharacterized protein OS=Arabis alpina GN=AALP_AA5G026200 PE=3 SV=1 +--MKNVMVIIDESNSSYDLLIWVLANLKDTieSSKFFIFAKQPQNSFTptsvlsssvgsaqmfypfssnaelmglaqaknmkialGILDKAKKICLNHGI-KAETLTDVGDPKTIIRKTIQEQKIDLLVMSDQQTRTLKK---------CLNNTNCSLLVARNG +>tr|A0A1V5NJ37|A0A1V5NJ37_9BACT Universal stress protein family protein OS=Bacteroidetes bacterium ADurb.Bin397 GN=BWY67_02110 PE=4 SV=1 +KPATKLVYTTDLKDDNIKAVNDLIPFASSMNSELIFLFVDDkihtdSEKISEDMSSKIRQLVQYPK-TSGYICTDPNVMNGISLFIEKQHVDMIAMLTHPRKFPQMLWDKSLTKKFSYHPNVPLLVLHAN +>tr|C5LZK0|C5LZK0_PERM5 Putative uncharacterized protein OS=Perkinsus marinus (strain ATCC 50983 / TXsc) GN=Pmar_PMAR003859 PE=4 SV=1 +-------------------------------------SIDESNDYERRFKNIASEYPQLET-TFDVAEATKDIRDTLMEYCSETEPDLVAIGSGGSTHYLK--LASLVEYVVRESPCDVLILREN +>tr|A0A0Q0YYL6|A0A0Q0YYL6_LEULA Uncharacterized protein OS=Leuconostoc lactis GN=AN225_03740 PE=4 SV=1 +-QMRHFLVAISKSLSSDNAIRWAYRQASAFDAPWTVVHVQQSGKSlAPAVQRHMSLAKKLGAK--TVILQGDHVVATLIAYIRETQVANLIIGKHVTRAWYQFGRSDIEDQILAAVPaLDIQIIPN- +>tr|A0A1F9BKY4|A0A1F9BKY4_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RBG_13_60_28 GN=A2Z73_01380 PE=4 SV=1 +-MAKKVLVAVNLKIPTPWAVFYGVHLAARLKAPLVLMAVFPGGvkkksktslaleaelpeEQRLWLEQVVEQCQQEEI-RLEIFLSSGPFFEEVAQFLASHrGIQFLVVGVPRDSPVTEREGSDAALKRIHHVfPGEILLVREQ +>tr|A0A1B7LG75|A0A1B7LG75_9FIRM Uncharacterized protein OS=Desulfotomaculum sp. LMa1 GN=A6M21_07440 PE=4 SV=1 +----NALLFTDLSQPSLSCAAYTAIMAKnNPEMKLTIITGSNENCAkknssdhwsgydvkfpqeQKILDRVKQVLENKGYNYEEWQADNCaRLAKKLVNYARDNNISTIIMPNHCKEDLKSMPVGHLASSVICLSEIPVVLVR-- +>tr|A0A1G9CAC8|A0A1G9CAC8_9GAMM Universal stress protein family protein OS=Dyella jiangningensis GN=SAMN04487785_10826 PE=4 SV=1 +RQLGHILAVYDGSPETILAVEHALLLARRIRASVFILGLYPPLDRAadapairaamvDELIAYIHAGRRLGL-DVDAQCPDEVSHGSVERFIADLHIDQIVVPKVGEH--SRPWTAALVRDLLQSCTVPLVIC--- +>tr|A0A1B7XBT7|A0A1B7XBT7_9DELT Uncharacterized protein OS=Halodesulfovibrio spirochaetisodalis GN=SP90_10635 PE=4 SV=1 +HGRRNVLLCVDGSRSSRNITEHVAKMLAGNPLHtITVLHVAPGKKYTtaspsvaflnkqfrnqrkaqcfisktshRVVAEAVELLVANGVREEAIETRlahSNDPASVIMETSDQGNFAVVAMGRSGTgnSFMRHMLMGSSVAHVWKKLNNACL----- +>tr|A0A1E2ZJJ4|A0A1E2ZJJ4_9GAMM Uncharacterized protein OS=Candidatus Thiodiazotropha endolucinida GN=CODIS_02010 PE=4 SV=1 +SKPLRVGAILDTGMASQKLLETITELGKSPDIGLTLFLTPDEETPQKAALQSYLSQQDPHQ-LINVVYINDLEPAALANQLKRSACDLLMISEQSP-----LLQGPTIKQILERLPYPTVVVR-- +>tr|F9UGX3|F9UGX3_9GAMM Uncharacterized protein OS=Thiocapsa marina 5811 GN=ThimaDRAFT_4176 PE=4 SV=1 +NGGPLVGVLYSGSEGATRALAIALELVVRHAANLVVILQPEISADT-ATLRGRvLEqLATLHE-QTRLVSLEGADAAGLSATVGKLGIDLLILDETNP-----LLARASLWNSLESLGCPVVIGR-- +>tr|A0A0F2J325|A0A0F2J325_9BACT UspA domain protein OS=Candidatus Magnetoovum chiemensis GN=MCHI_000422 PE=4 SV=1 +----KILCAVNGSERSFNALRSACRIAVKNSLSLNAFYVNSSCMYcpeltrwsyierriekeqdalsAEIYRKNRDIGKEFNI-NIDCLTSSGEVDAEINAFLNENGiYKMLVIGHNNKS----IFSENIVKNIIVNCNIPVLTTSSD +>tr|B9LVS4|B9LVS4_HALLT Uncharacterized protein OS=Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34) GN=Hlac_3261 PE=4 SV=1 +NALGRVLIASRHTKNAEAKVNTLLNIVDRDELlSVDLIHVADPDDPegeaegESVLKSMSSILTDQGIPsiRINQEVRKGsDVSFELRQAAR--NYDLFVMGATE-QDVGDEVFGPVGDYIVHEQDVAVLTLR-- +>tr|A0A1G2H7M4|A0A1G2H7M4_9BACT Uncharacterized protein OS=Candidatus Spechtbacteria bacterium RIFCSPHIGHO2_01_FULL_43_30 GN=A2827_00030 PE=4 SV=1 +RNPVRVLVPFrvkSHNQNNRLLAETVTAFSKFFDGKPTFLVIDDD-KKGSARQKIEKDLRDIGIPedlaGDIRIIHAGVVADRILEMSK--DFDVVIMGSSRGGSFSEITLGQTAELVLERCETTTIVVRHH +>tr|A0A075AII1|A0A075AII1_9TREM Uncharacterized protein OS=Opisthorchis viverrini GN=T265_02177 PE=4 SV=1 +---RKVCIPVNPKQDLRQIFHWYDEHIRHANDSLLFVSIVKPQFAIpvlagtaieisradvkrakEICREAMQLAKKHGLRANSYVYIGMNQKKTLTQFLREFKPDLVLVEKQVKNIILRKLTGdSQVKAVMASQNCVLVALPP- +>tr|K1YD23|K1YD23_9ZZZZ Uncharacterized protein (Fragment) OS=groundwater metagenome GN=ACD_75C01983G0001 PE=4 SV=1 +-MKKHFLVTISNDTDNLYGVRFACSFFDiLSEHTLTLLHICRLDSSDmqktltemwknpdddlrdkipigarRAIEKSKELLSQSKISidqviTKTVAERYGKVRDILNEGAE--GlYDAIILGRRAAYSLQWVFEKPageIAHAMIRNSCCasPLWICPE- +>tr|V4IY43|V4IY43_9DELT Uncharacterized protein OS=uncultured Desulfofustis sp. PB-SRB1 GN=N839_15480 PE=4 SV=1 +-MKKKFLVTVSNDFDQLTAIEFLCSFFLpQSRHQLTLYHICRLDSNDmnkallqmwdepdarvakrlsfgarKSLDRATDMLGSSQMSvddiiTKTVAERFGKVKDILSEGAG--GlYDAIILGKRASYALQWFFERPadeIAQAIVNDPSFstPLWICPE- +>tr|A0A0F2NFB5|A0A0F2NFB5_9DELT Uncharacterized protein OS=Desulfobulbaceae bacterium BRH_c16a GN=VR65_11495 PE=4 SV=1 +-MKKHFLVTISNDAEILYGIRFICSFFEdISNHQVTLLHICRRDAADmagtlsqmwngpsdgiqgrltvqakKSIDKAKEIFSRHRMSieqvmTKTCAERYGKVKDILTEGAK--GYDAVVLGRRASYSLQWMFERPadeTALAIIRDNCCttPLWICPE- +>tr|A0A0K9PK62|A0A0K9PK62_ZOSMR Protein kinase family protein, putative, expressed OS=Zostera marina GN=ZOSMA_235G00060 PE=4 SV=1 +---KKIFVGLSLNTDGRELLSWTIAKLAGAGDHVVAVHVCRKSDVqnrsvelDEYIRGFDALCRSKEVTLMGRIAEGTSKKKQLLKEANFFNATVVVVGVEKRLSSFWMPTALVAKYYKKKLKstMDFFAVHDG +>tr|M0LS16|M0LS16_9EURY Universal stress protein UspA OS=Halobiforma lacisalsi AJ5 GN=C445_05903 PE=4 SV=1 +--MQVYLVGTDSVHATAAVCDYLERRGAGDGKEIEVIAVAASGDEDgdrvgdrvgdrvgdrvgdgeepgerdAREALNVARVRLPFVDTLRTEYRDTALAPALAEVAAEHEVDEVIVGRTTSsseteaNGDGSTGAGSVVDGVLEGTSRPVVVVP-- +>tr|U7JFC7|U7JFC7_9ACTN Uncharacterized protein OS=Propionibacterium sp. KPL1844 GN=HMPREF1275_01426 PE=4 SV=1 +PMSDHPLVVAVFPGIPVRIIEAALEHARAHRCELVMAYVDESRVPVadgegsvplipdeertpcherevDLRTALEQVMSAHPDITWQFRYLAGLTDRELAHLAHTVNAGAFMVGTRAPGFRwqaKEWFDGSVAIQLSRRQRRPIIIVP-- +>tr|A0A1Y2CCD7|A0A1Y2CCD7_9FUNG Uncharacterized protein OS=Rhizoclosmatium globosum GN=BCR33DRAFT_717010 PE=4 SV=1 +--PQTVLVALDPTSPNEHTLRWVLsNLVKTERDVIVIITVIATEADREQTENAWNTLVSglslntmtKPV-PVILTAPTSSIGPRICAAVTDMNPSVLALGSSRNQLSSE---PSITNYCLANADCKVVVVRND +>tr|A0A0C2MW94|A0A0C2MW94_THEKT Uncharacterized protein OS=Thelohanellus kitauei GN=RF11_03286 PE=4 SV=1 +-----IVVGLDTSDYAEQVIEYVVKYIYRPGHHIIALAHFLGTKHIgshyiwnhveidcrtfcpkgkkkledslAKLENIEKMLNENKV-RYIRYFESGskKKEDYLWDIAREIGAQCIVVGISHLSMLKD-LRSHRGYDLSAKSGIPVFIVK-- +>tr|G4SVR7|G4SVR7_META2 Uncharacterized protein OS=Methylomicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z) GN=MEALZ_2446 PE=4 +---------YDGMEGSERAFKLAIDIAESQKSGLNIIlQRQSDNRIAEMEQQVKALLAGSNL-ASHFFIQSSRSYDSIMQYVLERGCSIVVLRADRTDPEAS---QSAASLFADRLGCPVLLV--- +>tr|A0A1Y1HQR0|A0A1Y1HQR0_KLEFL Uncharacterized protein OS=Klebsormidium flaccidum GN=KFL_000670320 PE=4 SV=1 +----RVLIAVNDSPESRAALEWATENLIREGDQVLLYHLVKTPKLIpvttgmvpylkvapemqrahnavavhnatSLLRSCQRFCISKKVFAKVEVGRCDQREAELLRKVEQNGITHLVMGTSQPAKFslRPRKKPGLTARICQAASCHVILVDE- diff --git a/esm/source/examples/data/some_proteins.fasta b/esm/source/examples/data/some_proteins.fasta new file mode 100644 index 0000000000000000000000000000000000000000..6b854198d8fd6a1419d74a4f5f6c4f57da96fbd7 --- /dev/null +++ b/esm/source/examples/data/some_proteins.fasta @@ -0,0 +1,30 @@ +>UniRef50_A0A1E3NP16 +AVIYYRFRSQKPDHIATIKFDGTGLTVFELKRDIILANNLLHSTDVDIVLYSTEDIQDTKSWGYQNGGSSSAGERELDDDNEVVPRSTTVLVRRTMTPKKNKGNVQRYVAGKPRLQVSGTNSVNKSISLGNNVGGTMNFGDAATNGDEDDMIKKMFSVQDEQWSQQQDVMATATRVDNFRTNVNEPVPEYYICYKCGEKGKHHIKNCPKNNDPNWEGVRVRKTTGIPKSHLKAIENPEDTIRDSNSSGNTTYMVNDEGKYVVAVADTKAWEKYQKTKKGESGGYLNGDVDVDDGELKDPETGKLWKSPVRIPCCNKIFSRKIIEDKLIDSDFTCPSCGKEQIYLDTLVADEELQAKVDEYVKNLSENKNNDGNSPKRRQVNPAGATANTSQLPQIPMMPMPPINMQMPPMNIGMPPFMPFMPMPGMNP +>UniRef50_UPI000836A30F +MTLRTLLALSILALAAAATVQARPGAPPCSPLGLKYQPGACEKWKREHPDVNPDGVVQTVTIVNNSSSVLGGYVTFWHANNEHTDVDLPGVKPGETWTANGSWTVGQAPYYLLYSSFQDSYGDPVTFYAVPISKYPALAKKLPPEPDNCQSNHFRMVFGDGPQYVYEQHSGAVVTGGQTDKNTLCQILGCPTGGSTAGGLNTQNRTTSRSAPQPVYFRSCDP +>UniRef50_A0A2G8L8Y3 +MAQKRYEENLSPYAELFRSKLIEDFHLLESFDEHGKSDAPKYYSKDFEDPARQDKMMLENPHGLVKFQVYSRKEPGEHFMLVLILSNSIALGLQAEVSESDDPKFAGLKLALDIFDYCSLFLFMVEIILKWIDNFWSFWSDNWNIFDFAVTVGSFVPEIINFFAGDIGGSMVRVIVRNLRVFRILRSLKMVSRFRQVRLIALAIGKAFSAITFIMLLLFTFLYIFAITGIIFFDTYTRSERQDLKYKDSFRSLPRAMITLFQLFTLDQWYKLLNDMWKVMDSMIPLGYIILWICIGSFIFRNVFVGIMVNNFQSIRNDLFEEVKEQEAARQIIQDTEKFNEELSRQEKKLNANRRGTLYQSPTVQPPKPNQPQPSQLAGLDNSETDEQSVSQEDESNTDGQTSLSGTDSYDLLGESSDSLFRRSSDGMIDKDKLSTNWEKTVHDNLTLLTSTPSETLWPRDTLFRYFQLMESLMENLQERQDLQDLAYHSLLQIFDSFDTSA +>UniRef50_A0A1D5ZRM3 +MPCVAHECHPRLPAANHCRSLSCLGTPAAGWSSGDDDREEDELDTKQVILNEMRNREMRKRSSRCSVDSPTLSGAFAWSFTPLHPRSSIEKVSCTEEEKEAASDSDNESEAFFSVKSFFTRSTSRAATVASSTDMDPPATWEGLRGCEGWPFGLCP +>UniRef50_UPI0003108055 +MPADAREYLESKHATRRFDRPAEVAGVVAFLLSDDTSFVIGAGYLVDGGYTALRAARGRLGPRRQAAPAVKLLPNTDSPR +>UniRef50_A0A223SCH7 +MGPPRWWKGITGLAAVVHRADPEDKADLYAKMGLYLEYHPETRIVEARIKPRLHDVCESKVSEGGLEPPCP +>UniRef50_A0A090SUK6 +MKTPEDRVFRATDEYSDFVMACRYKGNEREFVIASHDKLNEAQVETLTSYLSGEWFKKTYITGIMNDSDGVLSQHEEYGDEVFCQPLDELRVDRYIMMV +>UniRef50_V4AGU2 +MHLGSIYLMVVLLIYFAYTDDRKERENVDVINPEENLVQDDEQYVGDSTENIEKSGSEEEEEDKEAIEEEEDEEEELNYRYIPEPAQDIVDNGKKYIQVHCSFKQDESLIRHPSNCSRYFVCSYGVVEEMPVCDDGEVFSIQVSECVKKGSENDDCDKLPFDSPPEITRGTQPSLIWHPRHKSPRSQFRQPTTLQMKVPHIELESFTCSATGKVLSHHSENCAWYYNCSAHPDAVMQTFYSGFIMECPYPQLFSTETKQCEDFEDVKCGDRYEPKSPCDYRANHCHETSHCIPCWVRYASCLELPDGLNPWSELEWKPFFVECYKERTVFQGVCDKSAVFSPLTRACETPYSIPRQHGGWRPVCDGRRDGIYADEYGRCDIYYVCKGYIFTGFFRCEKGEMFNPVISICQKPEAVPYPCGDLEMPNICESSLNGYHLDMFGRCTHYFECKDQQLEGISMCPSGIFNPELQICESSRDQPKPCGNLTNLCTHKNDGFHSDENDCTKVFQCERGLTMTSYDCSGSVRTECDVCNTPTECNDKPNGLYPNLKEGVGYYYDCVRSQIQNHYKCDKEKGGPIFNPVKQRCFYPEDLCKEVFSLKIAW +>UniRef50_R5PKX9 +MQGGEQDVFEHRQVREKVIALKNHADAAAQGAAEFERLSFEQDVAALDGFETDQAAQKRGFAAARRPENHRDFFVVKREVDAVENHSVAELLYETARFQNNVIGHFYAFHFFSRALAASDTGQHARK +>UniRef50_UPI0003674933 +MKKKEDILNLEHTLLPWMGRTMKVLDYFIGDFLNLKGIELTKVQWILLKKLNEQNGQPQQNLAFLTNRDKASLARLITTMEKKKLVERIPSKIDGRINHIFITKHGCEILQKSAPVIEKVVGCIQEGISPEEIETVIKVMQKVNNNINRASN +>UniRef50_E9K9Y4 +MADNVLMAYHIVHDPDERAKHVLNTKKLYKWRITEKTKGTPVVGNVALVQTQFAKRTPVMIYATKEVANDLSDLQPVKVFTNNRDQETVNQTFDDLMR +>UniRef50_A0A2C9LWN7 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-0,0 +1,56 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import torch +from fairscale.nn.data_parallel import FullyShardedDataParallel as FSDP +from fairscale.nn.wrap import enable_wrap, wrap + +import esm + +# init the distributed world with world_size 1 +url = "tcp://localhost:23456" +torch.distributed.init_process_group(backend="nccl", init_method=url, world_size=1, rank=0) + +# download model data from the hub +model_name = "esm2_t48_15B_UR50D" +model_data, regression_data = esm.pretrained._download_model_and_regression_data(model_name) + +# initialize the model with FSDP wrapper +fsdp_params = dict( + mixed_precision=True, + flatten_parameters=True, + state_dict_device=torch.device("cpu"), # reduce GPU mem usage + cpu_offload=True, # enable cpu offloading +) +with enable_wrap(wrapper_cls=FSDP, **fsdp_params): + model, vocab = esm.pretrained.load_model_and_alphabet_core( + model_name, model_data, regression_data + ) + batch_converter = vocab.get_batch_converter() + model.eval() + + # Wrap each layer in FSDP separately + for name, child in model.named_children(): + if name == "layers": + for layer_name, layer in child.named_children(): + wrapped_layer = wrap(layer) + setattr(child, layer_name, wrapped_layer) + model = wrap(model) + +data = [ + ("protein1", "MKTVRQERLKSIVRILERSKEPVSGAQLAEELSVSRQVIVQDIAYLRSLGYNIVATPRGYVLAGG"), + ("protein2", "KALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEE"), + ( + "protein2 with mask", + "KALTARQQEVFDLIRDISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEE", + ), + ("protein3", "K A I S Q"), +] + +batch_labels, batch_strs, batch_tokens = batch_converter(data) +batch_tokens = batch_tokens.cuda() +with torch.no_grad(): + results = model(batch_tokens, repr_layers=[48], return_contacts=True) +print(results) diff --git a/esm/source/examples/esm_structural_dataset.ipynb b/esm/source/examples/esm_structural_dataset.ipynb new file mode 100644 index 0000000000000000000000000000000000000000..23a6f7a6a4f7f7bc616dc8a41085d4881969e839 --- /dev/null +++ b/esm/source/examples/esm_structural_dataset.ipynb @@ -0,0 +1,332 @@ +{ + "cells": [ + { + "cell_type": "markdown", + "metadata": { + "tags": [] + }, + "source": [ + "# Structural Split Dataset\n", + "\n", + "This shows how to load the structural holdout datasets described in Insert Section of our paper\n", + "\n", + "There are two tar files you will need. **The `StructureDataset` class will download these for you.**\n", + "- [The data splits](https://dl.fbaipublicfiles.com/fair-esm/structural-data/splits.tar.gz)\n", + "- [The pickle files containing sequence data, secondary structure labels, distance maps, and 3d coordinates](https://dl.fbaipublicfiles.com/fair-esm/structural-data/pkl.tar.gz)\n" + ] + }, + { + "cell_type": "code", + "execution_count": 1, + "metadata": {}, + "outputs": [], + "source": [ + "# Install esm:\n", + "# !pip install git+https://github.com/facebookresearch/esm.git" + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "metadata": {}, + "outputs": [], + "source": [ + "from pathlib import Path\n", + "import seaborn as sns\n", + "import matplotlib.pyplot as plt\n", + "import os\n", + "import torch\n", + "\n", + "import esm\n", + "from esm.data import ESMStructuralSplitDataset\n" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "# Loading the splits\n", + "\n", + "Given the same root path, `ESMStructuralSplitDataset` will download the dataset only the first time it is initialized. Any other time, it will check if the folder exists and exit early." + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n", + "Files already downloaded and verified\n" + ] + } + ], + "source": [ + "for split_level in ['family', 'superfamily', 'fold']:\n", + " for cv_partition in ['0', '1', '2', '3', '4']:\n", + " esm_structural_train = ESMStructuralSplitDataset(\n", + " split_level=split_level, \n", + " cv_partition=cv_partition, \n", + " split='train', \n", + " root_path = os.path.expanduser('~/.cache/torch/data/esm'),\n", + " download=True\n", + " )\n", + " esm_structural_valid = ESMStructuralSplitDataset(\n", + " split_level=split_level, \n", + " cv_partition=cv_partition, \n", + " split='valid', \n", + " root_path = os.path.expanduser('~/.cache/torch/data/esm'),\n", + " download=True\n", + " )" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "# Examine a single sample\n", + "\n", + "Each element is a dict with\n", + "- `seq` : string\n", + "- `ssp` : string\n", + "- `dist` : np.array\n", + "- `coords` : np.array" + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Files already downloaded and verified\n", + "dict_keys(['seq', 'ssp', 'dist', 'coords'])\n", + "\n", + "sequence MKTVRQERLKSIVRILERSKEPVSGAQLAEELSVSRQVIVQDIAYLRSLGYNIVATPRGYVLAGG\n", + "\n", + "SSP labels XHHHHHHHHHHHHHHHHH-SS-B-HHHHHHHHTS-HHHHHHHHHHHHHHT---EEETTEEE--TT\n" + ] + } + ], + "source": [ + "esm_structural_train = ESMStructuralSplitDataset(\n", + " split_level='superfamily', \n", + " cv_partition='4', \n", + " split='train', \n", + " root_path = os.path.expanduser('~/.cache/torch/data/esm'),\n", + " download=True\n", + ")\n", + "ele = esm_structural_train[0]\n", + "print(ele.keys()) \n", + "print()\n", + "print('sequence', ele['seq'])\n", + "print()\n", + "print('SSP labels', ele['ssp'])\n" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "## Visualize 3d Coordinates" + ] + }, + { + "cell_type": "code", + "execution_count": 7, + "metadata": {}, + "outputs": [], + "source": [ + "coords = ele['coords']\n", + "xs = coords[:,0]\n", + "ys = coords[:,1]\n", + "zs = coords[:,2]" + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "metadata": {}, + "outputs": [ + { + "data": { + "image/png": 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+ "text/plain": [ + "
" + ] + }, + "metadata": { + "needs_background": "light" + }, + "output_type": "display_data" + } + ], + "source": [ + "fig = plt.figure(figsize=(10,10))\n", + "ax = fig.add_subplot(111, projection='3d')\n", + "ax.set_title('3D coordinates of $C_{b}$ backbone structure')\n", + "N = ele['coords'].shape[0]\n", + "\n", + "for i in range(ele['coords'].shape[0] - 1):\n", + " ax.plot(\n", + " xs[i:i+2], ys[i:i+2], zs[i:i+2], \n", + " color=plt.cm.viridis(i/N),\n", + " marker='o'\n", + " )" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "## Visualize Distance + Contact Map" + ] + }, + { + "cell_type": "code", + "execution_count": 8, + "metadata": {}, + "outputs": [ + { + "data": { + "image/png": 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", + "text/plain": [ + "
" + ] + }, + "metadata": { + "needs_background": "light" + }, + "output_type": "display_data" + } + ], + "source": [ + "fig, ax = plt.subplots(1, 2, figsize=(20, 9))\n", + "sns.heatmap(ele['dist'], ax=ax[0])\n", + "sns.heatmap(ele['dist'] < 8, ax=ax[1])\n", + "ax[0].set_title('Distance Map')\n", + "ax[1].set_title('Contact Map')\n", + "plt.show()" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "## ESM-2 unsupervised self-attention map contact predictions" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "Note, this matches the `Quickstart` code in the README.\n", + "\n", + "The contact prediction comes from a sparse linear combination of the self-attention maps, trained with logistic regression on a few proteins, as described in our paper \"Transformer protein language models are unsupervised structure learners\"." + ] + }, + { + "cell_type": "code", + "execution_count": 9, + "metadata": {}, + "outputs": [ + { + "data": { + "image/png": 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", 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" + ] + }, + "metadata": { + "needs_background": "light" + }, + "output_type": "display_data" + } + ], + "source": [ + "model, alphabet = esm.pretrained.esm2_t33_650M_UR50D()\n", + "batch_converter = alphabet.get_batch_converter()\n", + "data = [(i, esm_structural_train[i]['seq']) for i in [0,1]]\n", + "batch_labels, batch_strs, batch_tokens = batch_converter(data)\n", + "batch_lens = (batch_tokens != alphabet.padding_idx).sum(1)\n", + "with torch.no_grad():\n", + " results = model(batch_tokens, repr_layers=[33], return_contacts=True)\n", + "for (_, seq), tokens_len, attention_contacts in zip(data, batch_lens, results[\"contacts\"]):\n", + " plt.matshow(attention_contacts[: tokens_len, : tokens_len])\n", + " plt.title(seq)" + ] + } + ], + "metadata": { + "kernelspec": { + "display_name": "Python 3.8.10 64-bit", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.8.10" + }, + "vscode": { + "interpreter": { + "hash": "916dbcbb3f70747c44a77c7bcd40155683ae19c65e1c03b4aa3499c5328201f1" + } + } + }, + "nbformat": 4, + "nbformat_minor": 4 +} diff --git a/esm/source/examples/inverse_folding/README.md b/esm/source/examples/inverse_folding/README.md new file mode 100644 index 0000000000000000000000000000000000000000..ec49cccd245f99fb6950bcfc501aed577afda086 --- /dev/null +++ b/esm/source/examples/inverse_folding/README.md @@ -0,0 +1,258 @@ +# Inverse folding with ESM-IF1 + +The ESM-IF1 inverse folding model is built for predicting protein sequences +from their backbone atom coordinates. We provide scripts here 1) to sample sequence +designs for a given structure and 2) to score sequences for a given structure. + +Trained with 12M protein structures predicted by AlphaFold2, the ESM-IF1 +model consists of invariant geometric input processing layers followed by a +sequence-to-sequence transformer, and achieves 51% native sequence recovery on +structurally held-out backbones with 72% recovery for buried residues. +The model is also trained with span masking to tolerate missing backbone +coordinates and therefore can predict sequences for partially masked structures. + +More details in our bioRxiv [pre-print](https://doi.org/10.1101/2022.04.10.487779). + +![Illustration](illustration.png) + +## Recommended environment +It is highly recommended to start a new conda environment from scratch due to +potential CUDA compatability issues between pytorch and the pytorch-geometric +package required for the inverse folding model. + +To set up a new conda environment with required packages, + +``` +conda create -n inverse python=3.9 +conda activate inverse +conda install pytorch cudatoolkit=11.3 -c pytorch +conda install pyg -c pyg -c conda-forge +conda install pip +pip install biotite +pip install git+https://github.com/facebookresearch/esm.git +``` + +## Quickstart + +### Sample sequence designs for a given structure +To sample sequences for a given structure in PDB or mmCIF format, use the +`sample_sequences.py` script. The input file can have either `.pdb` or +`.cif` as suffix. + +For example, to sample 3 sequence designs for the golgi casein kinase structure +(PDB [5YH2](https://www.rcsb.org/structure/5yh2); [PDB Molecule of the Month +from January 2022](https://pdb101.rcsb.org/motm/265)), we can run the following +command from the `examples/inverse_folding` directory: +``` +python sample_sequences.py data/5YH2.pdb \ + --chain C --temperature 1 --num-samples 3 \ + --outpath output/sampled_sequences.fasta +``` + +The sampled sequences will be saved in a fasta format to the specified output file. + +**By default, the script only loads the backbone of the specified target chain +as model input.** To instead use the entire complex backbone as model input for +conditioning, use the `--multichain-backbone` flag to load all chains. (In the +example below, the encoder loads the backbone of all chains as input to the +encoder, and the decoder samples sequences for chain C.) +``` +python sample_sequences.py data/5YH2.pdb \ + --chain C --temperature 1 --num-samples 3 \ + --outpath output/sampled_sequences_multichain.fasta \ + --multichain-backbone +``` + +The temperature parameter controls the sharpness of the probability +distribution for sequence sampling. Higher sampling temperatures yield more +diverse sequences but likely with lower native sequence recovery. +The default sampling temperature is 1. To optimize for native sequence +recovery, we recommend sampling with low temperature such as 1e-6. + +**We recommend trying both the single-chain and multi-chain design modes.** While in +our paper we showed that conditioning on the entire multi-chain backbone often +reduces perplexity and increases sequence recovery, on some proteins the +single-chain performance is better. + +Sometimes, one failure mode in sampled sequences is a high number of repeated +amino acids, e.g. `EEEEEEEE`. We recommend checking for that and filtering out +sampled sequences with long repeats. + +### Scoring sequences +To score the conditional log-likelihoods for sequences conditioned on a given +structure, use the `score_log_likelihoods.py` script. + +For example, to score the sequences in `data/5YH2_mutated_seqs.fasta` +according to the structure in `data/5YH2.pdb`, we can run +the following command from the `examples/inverse_folding` directory: +``` +python score_log_likelihoods.py data/5YH2.pdb \ + data/5YH2_mutated_seqs.fasta --chain C \ + --outpath output/5YH2_mutated_seqs_scores.csv +``` + +The conditional log-likelihoods are saved in a csv format in the specified output path. +The output values are the average log-likelihoods averaged over all amino acids in a sequence. + +**By default, the script only loads the backbone of the specified target chain +as model input.** To instead use the entire complex backbone as model input for +conditioning, use the `--multichain-backbone` flag to load all chains. (In the +example below, the encoder loads the backbone of all chains as input to the +encoder, and the decoder scores sequences for chain C.) +``` +python score_log_likelihoods.py data/5YH2.pdb \ + data/5YH2_mutated_seqs.fasta --chain C \ + --outpath output/5YH2_mutated_seqs_scores.csv \ + --multichain-backbone +``` + +We recommend trying both the single-chain and multi-chain design modes. While in +our paper we showed that conditioning on the entire multi-chain backbone often +reduces perplexity and increases sequence recovery, on some proteins the +single-chain performance is better. + +## General usage + +### Load model +The `esm_if1_gvp4_t16_142M_UR50` function loads the pretrained model and its +corresponding alphabet. The alphabet represents the amino acids and the special +tokens encoded by the model. + +**Update**: It is important to set the model in eval mode to avoid random +dropout from training mode for best performance. + +``` +import esm.inverse_folding +model, alphabet = esm.pretrained.esm_if1_gvp4_t16_142M_UR50() +model = model.eval() +``` + +### Input format +The input to the model is a list of backbone atom coordinates for the N, CA, C +atoms in each amino acid. For each structure, the coordinate list `coords` would +be of shape L x 3 x 3, where L is the number of amino acids in the structure. +`coords[i][0]` is the 3D coordinate for the N atom in amino acid `i`, +`coords[i][1]` is the 3D coordinate for the CA atom in amino acid `i`, and +`coords[i][2]` is the 3D coordinate for the C atom in amino acid `i`. + +### Load input data from PDB and mmCIF file formats +To load a single chain from PDB and mmCIF file formats and extract the backbone +coordinates of the N, CA, C atoms as model input, +``` +import esm.inverse_folding +structure = esm.inverse_folding.util.load_structure(fpath, chain_id) +coords, seq = esm.inverse_folding.util.extract_coords_from_structure(structure) +``` +Note this only loads the specified chain. + +To load multiple chains for the multichain complex use cases, list all chain ids +when loading the structure, e.g. `chain_ids = ['A', 'B', 'C']`: +``` +structure = esm.inverse_folding.util.load_structure(fpath, chain_ids) +coords, native_seqs = esm.inverse_folding.multichain_util.extract_coords_from_complex(structure) +``` + +### Example Jupyter notebook +See `examples/inverse_folding/notebook.ipynb` for examples of sampling sequences, +calculating conditional log-likelihoods, and extracting encoder output as +structure representation (on a single chain). + +This notebook is also available on colab: + +[](https://colab.research.google.com/github/facebookresearch/esm/blob/master/examples/inverse_folding/notebook.ipynb) + +For multichain complexes, ESM-IF1 can design sequences for a specific chain in the complex, +conditioned on the backbone structure of the entire multichain complex. + +See `examples/inverse_folding/notebook_multichain.ipynb` for sequence design and sequence scoring in multichain complexes, or find the notebook on colab: + +[](https://colab.research.google.com/github/facebookresearch/esm/blob/master/examples/inverse_folding/notebook_multichain.ipynb) + +### Sample sequence designs +To sample sequences for a given set of backbone coordinates for a single chain, +``` +sampled_seq = model.sample(coords, temperature=T) +``` +where `coords` is an array as described in the above section on input format. + +To sample sequences for a given chain in a multichain complex, +``` +import esm.inverse_folding +sampled_seq = esm.inverse_folding.multichain_util.sample_sequence_in_complex( + model, coords, target_chain_id, temperature=T +) +``` +where `coords` is a dictionary mapping chain ids to backbone coordinate arrays. + +The temperature parameter controls the ``sharpness`` of the probability +distribution for sequence sampling. Higher sampling temperatures yield more +diverse sequences but likely with lower native sequence recovery. +The default sampling temperature is `T=1`. To optimize for native sequence +recovery, we recommend sampling with low temperature such as `T=1e-6`. + +### Scoring sequences +To score the conditional log-likelihoods for sequences conditioned on a given +set of backbone coordinates for a single chain, use the `score_sequence` function, +``` +ll_fullseq, ll_withcoord = esm.inverse_folding.util.score_sequence(model, alphabet, coords, seq) +``` + +The first returned value ``ll_fullseq`` is the average log-likelihood averaged +over all amino acids in a sequence. +The second return value ``ll_withcoord`` is averaged only over those amino acids +with associated backbone coordinates in the input, i.e., excluding those with +missing backbone coordinates. + +For multichain complexes, +``` +ll_fullseq, ll_withcoord = esm.inverse_folding.multichain_util.score_sequence_in_complex( + model, alphabet, coords, target_chain_id, target_seq +) +``` +where `coords` is a dictionary mapping chain ids to backbone coordinate arrays. + +### Partially masking backbone coordinates +To mask a parts of the input backbone coordinates, simply set those coordinate +values to `np.inf`. For example, to mask the backbone coordinates for the first +ten amino acid in the structure, +``` +coords[:10, :] = float('inf') +``` + +### Encoder output as structure representation +To extract the encoder output as structure representation, +``` +rep = esm.inverse_folding.util.get_encoder_output(model, alphabet, coords) +``` +For a set of input coordinates with L amino acids, the encoder output will have +shape L x 512. + +Or, for multichain complex, +``` +rep = esm.inverse_folding.multichain_util.get_encoder_output_for_complex( + model, alphabet, coords, target_chain_id +) +``` + +## Data split + +The CATH v4.3 data are available at the following links: +- [Backbone coordinates and sequences](https://dl.fbaipublicfiles.com/fair-esm/data/cath4.3_topologysplit_202206/chain_set.jsonl) +- [Split](https://dl.fbaipublicfiles.com/fair-esm/data/cath4.3_topologysplit_202206/splits.json) + +That's it for now, have fun! + +## Acknowledgements +The invariant geometric input processing layers are from the [Geometric Vector +Perceptron PyTorch repo](https://github.com/drorlab/gvp-pytorch) by Bowen Jing, +Stephan Eismann, Pratham Soni, Patricia Suriana, Raphael Townshend, and Ron +Dror. + +The input data pipeline is adapted from the [Geometric Vector Perceptron PyTorch +repo](https://github.com/drorlab/gvp-pytorch) and the [Generative Models for +Graph-Based Protein Design +repo](https://github.com/jingraham/neurips19-graph-protein-design) by John +Ingraham, Vikas Garg, Regina Barzilay, and Tommi Jaakkola. + +The Transformer implementation is adapted from +[fairseq](https://github.com/pytorch/fairseq). diff --git a/esm/source/examples/inverse_folding/data/4uv3.cif b/esm/source/examples/inverse_folding/data/4uv3.cif new file mode 100644 index 0000000000000000000000000000000000000000..165e900bcf705242264dbe9d5894e6345a39b4f5 --- /dev/null +++ b/esm/source/examples/inverse_folding/data/4uv3.cif @@ -0,0 +1,41776 @@ +data_4UV3 +# +_entry.id 4UV3 +# +_audit_conform.dict_name mmcif_pdbx.dic +_audit_conform.dict_version 5.279 +_audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic +# +loop_ +_database_2.database_id +_database_2.database_code +PDB 4UV3 +PDBE EBI-61433 +WWPDB D_1290061433 +# +_pdbx_database_related.db_name PDB +_pdbx_database_related.db_id 4UV2 +_pdbx_database_related.content_type unspecified +_pdbx_database_related.details 'STRUCTURE OF THE CURLI TRANSPORT LIPOPROTEIN CSGG IN A NON-LIPIDATED, PRE-PORE CONFORMATION' +# +_pdbx_database_status.status_code REL +_pdbx_database_status.entry_id 4UV3 +_pdbx_database_status.deposit_site PDBE +_pdbx_database_status.process_site PDBE +_pdbx_database_status.SG_entry . +_pdbx_database_status.recvd_initial_deposition_date 2014-08-04 +_pdbx_database_status.pdb_format_compatible Y +_pdbx_database_status.status_code_sf ? +_pdbx_database_status.status_code_mr ? +_pdbx_database_status.status_code_cs ? +_pdbx_database_status.methods_development_category ? +# +loop_ +_audit_author.name +_audit_author.pdbx_ordinal +'Goyal, P.' 1 +'Krasteva, P.V.' 2 +'Gerven, N.V.' 3 +'Gubellini, F.' 4 +'Broeck, I.V.D.' 5 +'Troupiotis-Tsailaki, A.' 6 +'Jonckheere, W.' 7 +'Pehau-Arnaudet, G.' 8 +'Pinkner, J.S.' 9 +'Chapman, M.R.' 10 +'Hultgren, S.J.' 11 +'Howorka, S.' 12 +'Fronzes, R.' 13 +'Remaut, H.' 14 +# +_citation.id primary +_citation.title 'Structural and Mechanistic Insights Into the Bacterial Amyloid Secretion Channel Csgg.' +_citation.journal_abbrev Nature +_citation.journal_volume 516 +_citation.page_first 250 +_citation.page_last ? +_citation.year 2014 +_citation.journal_id_ASTM NATUAS +_citation.country UK +_citation.journal_id_ISSN 0028-0836 +_citation.journal_id_CSD 0006 +_citation.book_publisher ? +_citation.pdbx_database_id_PubMed 25219853 +_citation.pdbx_database_id_DOI 10.1038/NATURE13768 +# +loop_ +_citation_author.citation_id +_citation_author.name +_citation_author.ordinal +primary 'Goyal, P.' 1 +primary 'Krasteva, P.V.' 2 +primary 'Van Gerven, N.' 3 +primary 'Gubellini, F.' 4 +primary 'Van Den Broeck, I.' 5 +primary 'Troupiotis-Tsailaki, A.' 6 +primary 'Jonckheere, W.' 7 +primary 'Pehau-Arnaudet, G.' 8 +primary 'Pinkner, J.S.' 9 +primary 'Chapman, M.R.' 10 +primary 'Hultgren, S.J.' 11 +primary 'Howorka, S.' 12 +primary 'Fronzes, R.' 13 +primary 'Remaut, H.' 14 +# +_cell.entry_id 4UV3 +_cell.length_a 161.934 +_cell.length_b 372.847 +_cell.length_c 161.972 +_cell.angle_alpha 90.00 +_cell.angle_beta 92.90 +_cell.angle_gamma 90.00 +_cell.Z_PDB 72 +_cell.pdbx_unique_axis ? +# +_symmetry.entry_id 4UV3 +_symmetry.space_group_name_H-M 'C 1 2 1' +_symmetry.pdbx_full_space_group_name_H-M ? +_symmetry.cell_setting ? +_symmetry.Int_Tables_number 5 +# +_entity.id 1 +_entity.type polymer +_entity.src_method man +_entity.pdbx_description 'CURLI PRODUCTION ASSEMBLY/TRANSPORT COMPONENT CSGG' +_entity.formula_weight 28909.893 +_entity.pdbx_number_of_molecules 18 +_entity.pdbx_ec ? +_entity.pdbx_mutation ? +_entity.pdbx_fragment ? +_entity.details LIPOPROTEIN +# +_entity_poly.entity_id 1 +_entity_poly.type 'polypeptide(L)' +_entity_poly.nstd_linkage no +_entity_poly.nstd_monomer no +_entity_poly.pdbx_seq_one_letter_code +;CLTAPPKEAARPTLMPRAQSYKDLTHLPAPTGKIFVSVYNIQDETGQFKPYPASNFSTAVPQSATAMLVTALKDSRWFIP +LERQGLQNLLNERKIIRAAQENGTVAINNRIPLQSLTAANIMVEGSIIGYESNVKSGGVGARYFGIGADTQYQLDQIAVN +LRVVNVSTGEILSSVNTSKTILSYEVQAGVFRFIDYQRLLEGEVGYTSNEPVMLCLMSAIETGVIFLINDGIDRGLWDLQ +NKAERQNDILVKYRHMSVPPES +; +_entity_poly.pdbx_seq_one_letter_code_can +;CLTAPPKEAARPTLMPRAQSYKDLTHLPAPTGKIFVSVYNIQDETGQFKPYPASNFSTAVPQSATAMLVTALKDSRWFIP +LERQGLQNLLNERKIIRAAQENGTVAINNRIPLQSLTAANIMVEGSIIGYESNVKSGGVGARYFGIGADTQYQLDQIAVN +LRVVNVSTGEILSSVNTSKTILSYEVQAGVFRFIDYQRLLEGEVGYTSNEPVMLCLMSAIETGVIFLINDGIDRGLWDLQ +NKAERQNDILVKYRHMSVPPES +; +_entity_poly.pdbx_strand_id A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R +_entity_poly.pdbx_target_identifier ? +# +loop_ +_entity_poly_seq.entity_id +_entity_poly_seq.num +_entity_poly_seq.mon_id +_entity_poly_seq.hetero +1 1 CYS n +1 2 LEU n +1 3 THR n +1 4 ALA n +1 5 PRO n +1 6 PRO n +1 7 LYS n +1 8 GLU n +1 9 ALA n +1 10 ALA n +1 11 ARG n +1 12 PRO n +1 13 THR n +1 14 LEU n +1 15 MET n +1 16 PRO n +1 17 ARG n +1 18 ALA n +1 19 GLN n +1 20 SER n +1 21 TYR n +1 22 LYS n +1 23 ASP n +1 24 LEU n +1 25 THR n +1 26 HIS n +1 27 LEU n +1 28 PRO n +1 29 ALA n +1 30 PRO n +1 31 THR n +1 32 GLY n +1 33 LYS n +1 34 ILE n +1 35 PHE n +1 36 VAL n +1 37 SER n +1 38 VAL n +1 39 TYR n +1 40 ASN n +1 41 ILE n +1 42 GLN n +1 43 ASP n +1 44 GLU n +1 45 THR n +1 46 GLY n +1 47 GLN n +1 48 PHE n +1 49 LYS n +1 50 PRO n +1 51 TYR n +1 52 PRO n +1 53 ALA n +1 54 SER n +1 55 ASN n +1 56 PHE n +1 57 SER n +1 58 THR n +1 59 ALA n +1 60 VAL n +1 61 PRO n +1 62 GLN n +1 63 SER n +1 64 ALA n +1 65 THR n +1 66 ALA n +1 67 MET n +1 68 LEU n +1 69 VAL n +1 70 THR n +1 71 ALA n +1 72 LEU n +1 73 LYS n +1 74 ASP n +1 75 SER n +1 76 ARG n +1 77 TRP n +1 78 PHE n +1 79 ILE n +1 80 PRO n +1 81 LEU n +1 82 GLU n +1 83 ARG n +1 84 GLN n +1 85 GLY n +1 86 LEU n +1 87 GLN n +1 88 ASN n +1 89 LEU n +1 90 LEU n +1 91 ASN n +1 92 GLU n +1 93 ARG n +1 94 LYS n +1 95 ILE n +1 96 ILE n +1 97 ARG n +1 98 ALA n +1 99 ALA n +1 100 GLN n +1 101 GLU n +1 102 ASN n +1 103 GLY n +1 104 THR n +1 105 VAL n +1 106 ALA n +1 107 ILE n +1 108 ASN n +1 109 ASN n +1 110 ARG n +1 111 ILE n +1 112 PRO n +1 113 LEU n +1 114 GLN n +1 115 SER n +1 116 LEU n +1 117 THR n +1 118 ALA n +1 119 ALA n +1 120 ASN n +1 121 ILE n +1 122 MET n +1 123 VAL n +1 124 GLU n +1 125 GLY n +1 126 SER n +1 127 ILE n +1 128 ILE n +1 129 GLY n +1 130 TYR n +1 131 GLU n +1 132 SER n +1 133 ASN n +1 134 VAL n +1 135 LYS n +1 136 SER n +1 137 GLY n +1 138 GLY n +1 139 VAL n +1 140 GLY n +1 141 ALA n +1 142 ARG n +1 143 TYR n +1 144 PHE n +1 145 GLY n +1 146 ILE n +1 147 GLY n +1 148 ALA n +1 149 ASP n +1 150 THR n +1 151 GLN n +1 152 TYR n +1 153 GLN n +1 154 LEU n +1 155 ASP n +1 156 GLN n +1 157 ILE n +1 158 ALA n +1 159 VAL n +1 160 ASN n +1 161 LEU n +1 162 ARG n +1 163 VAL n +1 164 VAL n +1 165 ASN n +1 166 VAL n +1 167 SER n +1 168 THR n +1 169 GLY n +1 170 GLU n +1 171 ILE n +1 172 LEU n +1 173 SER n +1 174 SER n +1 175 VAL n +1 176 ASN n +1 177 THR n +1 178 SER n +1 179 LYS n +1 180 THR n +1 181 ILE n +1 182 LEU n +1 183 SER n +1 184 TYR n +1 185 GLU n +1 186 VAL n +1 187 GLN n +1 188 ALA n +1 189 GLY n +1 190 VAL n +1 191 PHE n +1 192 ARG n +1 193 PHE n +1 194 ILE n +1 195 ASP n +1 196 TYR n +1 197 GLN n +1 198 ARG n +1 199 LEU n +1 200 LEU n +1 201 GLU n +1 202 GLY n +1 203 GLU n +1 204 VAL n +1 205 GLY n +1 206 TYR n +1 207 THR n +1 208 SER n +1 209 ASN n +1 210 GLU n +1 211 PRO n +1 212 VAL n +1 213 MET n +1 214 LEU n +1 215 CYS n +1 216 LEU n +1 217 MET n +1 218 SER n +1 219 ALA n +1 220 ILE n +1 221 GLU n +1 222 THR n +1 223 GLY n +1 224 VAL n +1 225 ILE n +1 226 PHE n +1 227 LEU n +1 228 ILE n +1 229 ASN n +1 230 ASP n +1 231 GLY n +1 232 ILE n +1 233 ASP n +1 234 ARG n +1 235 GLY n +1 236 LEU n +1 237 TRP n +1 238 ASP n +1 239 LEU n +1 240 GLN n +1 241 ASN n +1 242 LYS n +1 243 ALA n +1 244 GLU n +1 245 ARG n +1 246 GLN n +1 247 ASN n +1 248 ASP n +1 249 ILE n +1 250 LEU n +1 251 VAL n +1 252 LYS n +1 253 TYR n +1 254 ARG n +1 255 HIS n +1 256 MET n +1 257 SER n +1 258 VAL n +1 259 PRO n +1 260 PRO n +1 261 GLU n +1 262 SER n +# +_entity_src_gen.entity_id 1 +_entity_src_gen.pdbx_src_id 1 +_entity_src_gen.pdbx_alt_source_flag sample +_entity_src_gen.pdbx_seq_type ? +_entity_src_gen.pdbx_beg_seq_num ? +_entity_src_gen.pdbx_end_seq_num ? +_entity_src_gen.gene_src_common_name ? +_entity_src_gen.gene_src_genus ? +_entity_src_gen.pdbx_gene_src_gene ? +_entity_src_gen.gene_src_species ? +_entity_src_gen.gene_src_strain ? +_entity_src_gen.gene_src_tissue ? +_entity_src_gen.gene_src_tissue_fraction ? +_entity_src_gen.gene_src_details ? +_entity_src_gen.pdbx_gene_src_fragment ? +_entity_src_gen.pdbx_gene_src_scientific_name 'ESCHERICHIA COLI STR. K-12 SUBSTR. MC4100' +_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 1403831 +_entity_src_gen.pdbx_gene_src_variant ? +_entity_src_gen.pdbx_gene_src_cell_line ? +_entity_src_gen.pdbx_gene_src_atcc ? +_entity_src_gen.pdbx_gene_src_organ ? +_entity_src_gen.pdbx_gene_src_organelle ? +_entity_src_gen.pdbx_gene_src_cell ? +_entity_src_gen.pdbx_gene_src_cellular_location ? +_entity_src_gen.host_org_common_name ? +_entity_src_gen.pdbx_host_org_scientific_name 'ESCHERICHIA COLI' +_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 469008 +_entity_src_gen.host_org_genus ? +_entity_src_gen.pdbx_host_org_gene ? +_entity_src_gen.pdbx_host_org_organ ? +_entity_src_gen.host_org_species ? +_entity_src_gen.pdbx_host_org_tissue ? +_entity_src_gen.pdbx_host_org_tissue_fraction ? +_entity_src_gen.pdbx_host_org_strain 'BL21(DE3)' +_entity_src_gen.pdbx_host_org_variant ? +_entity_src_gen.pdbx_host_org_cell_line ? +_entity_src_gen.pdbx_host_org_atcc ? +_entity_src_gen.pdbx_host_org_culture_collection ? +_entity_src_gen.pdbx_host_org_cell ? +_entity_src_gen.pdbx_host_org_organelle ? +_entity_src_gen.pdbx_host_org_cellular_location ? +_entity_src_gen.pdbx_host_org_vector_type PLASMID +_entity_src_gen.pdbx_host_org_vector ? +_entity_src_gen.host_org_details ? +_entity_src_gen.expression_system_id ? +_entity_src_gen.plasmid_name PASK-IBA3PLUS +_entity_src_gen.plasmid_details ? +_entity_src_gen.pdbx_description ? +# +_struct_ref.id 1 +_struct_ref.db_name UNP +_struct_ref.db_code CSGG_ECOLI +_struct_ref.entity_id 1 +_struct_ref.pdbx_seq_one_letter_code ? +_struct_ref.pdbx_align_begin ? +_struct_ref.pdbx_db_accession P0AEA2 +_struct_ref.pdbx_db_isoform ? +# +loop_ +_struct_ref_seq.align_id +_struct_ref_seq.ref_id +_struct_ref_seq.pdbx_PDB_id_code +_struct_ref_seq.pdbx_strand_id +_struct_ref_seq.seq_align_beg +_struct_ref_seq.pdbx_seq_align_beg_ins_code +_struct_ref_seq.seq_align_end +_struct_ref_seq.pdbx_seq_align_end_ins_code +_struct_ref_seq.pdbx_db_accession +_struct_ref_seq.db_align_beg +_struct_ref_seq.pdbx_db_align_beg_ins_code +_struct_ref_seq.db_align_end +_struct_ref_seq.pdbx_db_align_end_ins_code +_struct_ref_seq.pdbx_auth_seq_align_beg +_struct_ref_seq.pdbx_auth_seq_align_end +1 1 4UV3 A 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +2 1 4UV3 B 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +3 1 4UV3 C 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +4 1 4UV3 D 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +5 1 4UV3 E 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +6 1 4UV3 F 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +7 1 4UV3 G 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +8 1 4UV3 H 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +9 1 4UV3 I 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +10 1 4UV3 J 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +11 1 4UV3 K 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +12 1 4UV3 L 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +13 1 4UV3 M 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +14 1 4UV3 N 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +15 1 4UV3 O 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +16 1 4UV3 P 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +17 1 4UV3 Q 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +18 1 4UV3 R 1 ? 262 ? P0AEA2 16 ? 277 ? 1 262 +# +loop_ +_chem_comp.id +_chem_comp.type +_chem_comp.mon_nstd_flag +_chem_comp.name +_chem_comp.pdbx_synonyms +_chem_comp.formula +_chem_comp.formula_weight +ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 +ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 +ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 +ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 +CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 +GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 +GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 +GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 +HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 +ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 +LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 +LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 +MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 +PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 +PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 +SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 +THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 +TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 +TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 +VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 +# +_exptl.entry_id 4UV3 +_exptl.method 'X-RAY DIFFRACTION' +_exptl.crystals_number 1 +# +_exptl_crystal.id 1 +_exptl_crystal.density_meas ? +_exptl_crystal.density_Matthews 4.52 +_exptl_crystal.density_percent_sol 73 +_exptl_crystal.description +'DATA WERE ANISOTROPICALLY SCALED TO 3.6, 3.7 AND 3.8 ANGSTROM ALONG RECIPROCAL DIRECTIONS A, B AND C.' +# +_exptl_crystal_grow.crystal_id 1 +_exptl_crystal_grow.method ? +_exptl_crystal_grow.temp ? +_exptl_crystal_grow.temp_details ? +_exptl_crystal_grow.pH 8.5 +_exptl_crystal_grow.pdbx_pH_range ? +_exptl_crystal_grow.pdbx_details '100 MM TRIS-HCL PH 8.0, 8% PEG 4000, 100 MM NACL AND 500 MM MGCL2' +# +_diffrn.id 1 +_diffrn.ambient_temp 100 +_diffrn.ambient_temp_details ? +_diffrn.crystal_id 1 +# +_diffrn_detector.diffrn_id 1 +_diffrn_detector.detector PIXEL +_diffrn_detector.type 'DECTRIS PILATUS 6M' +_diffrn_detector.pdbx_collection_date 2011-10-31 +_diffrn_detector.details ? +# +_diffrn_radiation.diffrn_id 1 +_diffrn_radiation.wavelength_id 1 +_diffrn_radiation.pdbx_monochromatic_or_laue_m_l M +_diffrn_radiation.monochromator ? +_diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' +_diffrn_radiation.pdbx_scattering_type x-ray +# +_diffrn_radiation_wavelength.id 1 +_diffrn_radiation_wavelength.wavelength 0.9763 +_diffrn_radiation_wavelength.wt 1.0 +# +_diffrn_source.diffrn_id 1 +_diffrn_source.source SYNCHROTRON +_diffrn_source.type 'DIAMOND BEAMLINE I03' +_diffrn_source.pdbx_synchrotron_site Diamond +_diffrn_source.pdbx_synchrotron_beamline I03 +_diffrn_source.pdbx_wavelength 0.9763 +_diffrn_source.pdbx_wavelength_list ? +# +_reflns.pdbx_diffrn_id 1 +_reflns.pdbx_ordinal 1 +_reflns.entry_id 4UV3 +_reflns.observed_criterion_sigma_I 2.0 +_reflns.observed_criterion_sigma_F ? +_reflns.d_resolution_low 30.00 +_reflns.d_resolution_high 3.60 +_reflns.number_obs 102130 +_reflns.number_all ? +_reflns.percent_possible_obs 91.6 +_reflns.pdbx_Rmerge_I_obs 0.16 +_reflns.pdbx_Rsym_value ? +_reflns.pdbx_netI_over_sigmaI 6.80 +_reflns.B_iso_Wilson_estimate ? +_reflns.pdbx_redundancy 4.4 +# +_reflns_shell.pdbx_diffrn_id 1 +_reflns_shell.pdbx_ordinal 1 +_reflns_shell.d_res_high 3.60 +_reflns_shell.d_res_low 3.68 +_reflns_shell.percent_possible_all 27.3 +_reflns_shell.Rmerge_I_obs 0.91 +_reflns_shell.pdbx_Rsym_value ? +_reflns_shell.meanI_over_sigI_obs 1.89 +_reflns_shell.pdbx_redundancy 4.3 +# +_refine.pdbx_refine_id 'X-RAY DIFFRACTION' +_refine.entry_id 4UV3 +_refine.pdbx_diffrn_id 1 +_refine.pdbx_TLS_residual_ADP_flag ? +_refine.ls_number_reflns_obs 97020 +_refine.ls_number_reflns_all ? +_refine.pdbx_ls_sigma_I ? +_refine.pdbx_ls_sigma_F . +_refine.pdbx_data_cutoff_high_absF ? +_refine.pdbx_data_cutoff_low_absF ? +_refine.pdbx_data_cutoff_high_rms_absF ? +_refine.ls_d_res_low 30.00 +_refine.ls_d_res_high 3.59 +_refine.ls_percent_reflns_obs 91.50 +_refine.ls_R_factor_obs 0.29921 +_refine.ls_R_factor_all ? +_refine.ls_R_factor_R_work 0.29661 +_refine.ls_R_factor_R_free 0.34903 +_refine.ls_R_factor_R_free_error ? +_refine.ls_R_factor_R_free_error_details ? +_refine.ls_percent_reflns_R_free 5.0 +_refine.ls_number_reflns_R_free 5110 +_refine.ls_number_parameters ? +_refine.ls_number_restraints ? +_refine.occupancy_min ? +_refine.occupancy_max ? +_refine.correlation_coeff_Fo_to_Fc 0.813 +_refine.correlation_coeff_Fo_to_Fc_free 0.773 +_refine.B_iso_mean 115.072 +_refine.aniso_B[1][1] 2.18 +_refine.aniso_B[2][2] -3.72 +_refine.aniso_B[3][3] 1.56 +_refine.aniso_B[1][2] 0.00 +_refine.aniso_B[1][3] -0.41 +_refine.aniso_B[2][3] 0.00 +_refine.solvent_model_details 'BABINET MODEL WITH MASK' +_refine.solvent_model_param_ksol ? +_refine.solvent_model_param_bsol ? +_refine.pdbx_solvent_vdw_probe_radii 1.20 +_refine.pdbx_solvent_ion_probe_radii 0.80 +_refine.pdbx_solvent_shrinkage_radii 0.80 +_refine.pdbx_ls_cross_valid_method THROUGHOUT +_refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. U VALUES REFINED INDIVIDUALLY' +_refine.pdbx_starting_model 'PDB ENTRY 4UV2' +_refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' +_refine.pdbx_isotropic_thermal_model ? +_refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' +_refine.pdbx_stereochem_target_val_spec_case ? +_refine.pdbx_R_Free_selection_details RANDOM +_refine.pdbx_overall_ESU_R ? +_refine.pdbx_overall_ESU_R_Free 0.780 +_refine.overall_SU_ML 0.619 +_refine.pdbx_overall_phase_error ? +_refine.overall_SU_B 41.297 +_refine.overall_SU_R_Cruickshank_DPI ? +_refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? +_refine.pdbx_overall_SU_R_Blow_DPI ? +_refine.pdbx_overall_SU_R_free_Blow_DPI ? +# +_refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' +_refine_hist.cycle_id LAST +_refine_hist.pdbx_number_atoms_protein 34255 +_refine_hist.pdbx_number_atoms_nucleic_acid 0 +_refine_hist.pdbx_number_atoms_ligand 0 +_refine_hist.number_atoms_solvent 0 +_refine_hist.number_atoms_total 34255 +_refine_hist.d_res_high 3.59 +_refine_hist.d_res_low 30.00 +# +loop_ +_refine_ls_restr.type +_refine_ls_restr.dev_ideal +_refine_ls_restr.dev_ideal_target +_refine_ls_restr.weight +_refine_ls_restr.number +_refine_ls_restr.pdbx_refine_id +_refine_ls_restr.pdbx_restraint_function +r_bond_refined_d 0.011 0.019 ? 34795 'X-RAY DIFFRACTION' ? +r_bond_other_d 0.008 0.020 ? 33905 'X-RAY DIFFRACTION' ? +r_angle_refined_deg 1.364 1.967 ? 47212 'X-RAY DIFFRACTION' ? +r_angle_other_deg 1.300 3.000 ? 77774 'X-RAY DIFFRACTION' ? +r_dihedral_angle_1_deg 7.916 5.000 ? 4397 'X-RAY DIFFRACTION' ? +r_dihedral_angle_2_deg 42.665 24.832 ? 1517 'X-RAY DIFFRACTION' ? +r_dihedral_angle_3_deg 21.375 15.000 ? 5991 'X-RAY DIFFRACTION' ? +r_dihedral_angle_4_deg 17.873 15.000 ? 221 'X-RAY DIFFRACTION' ? +r_chiral_restr 0.070 0.200 ? 5513 'X-RAY DIFFRACTION' ? +r_gen_planes_refined 0.014 0.021 ? 39624 'X-RAY DIFFRACTION' ? +r_gen_planes_other 0.013 0.020 ? 7693 'X-RAY DIFFRACTION' ? +r_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? +r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? +r_nbtor_refined ? ? ? ? 'X-RAY DIFFRACTION' ? +r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? +r_xyhbond_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? +r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? +r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? +r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? +r_symmetry_vdw_refined ? ? ? ? 'X-RAY DIFFRACTION' ? +r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? +r_symmetry_hbond_refined ? ? ? ? 'X-RAY DIFFRACTION' ? +r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? +r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? +r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? +r_mcbond_it ? ? ? ? 'X-RAY DIFFRACTION' ? +r_mcbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? +r_mcangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? +r_mcangle_other ? ? ? ? 'X-RAY DIFFRACTION' ? +r_scbond_it ? ? ? ? 'X-RAY DIFFRACTION' ? +r_scbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? +r_scangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? +r_scangle_other ? ? ? ? 'X-RAY DIFFRACTION' ? +r_long_range_B_refined ? ? ? ? 'X-RAY DIFFRACTION' ? +r_long_range_B_other ? ? ? ? 'X-RAY DIFFRACTION' ? +r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? +r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? +r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? +# +loop_ +_refine_ls_restr_ncs.dom_id +_refine_ls_restr_ncs.pdbx_auth_asym_id +_refine_ls_restr_ncs.pdbx_number +_refine_ls_restr_ncs.rms_dev_position +_refine_ls_restr_ncs.weight_position +_refine_ls_restr_ncs.pdbx_type +_refine_ls_restr_ncs.pdbx_ens_id +_refine_ls_restr_ncs.pdbx_ordinal +_refine_ls_restr_ncs.pdbx_refine_id +_refine_ls_restr_ncs.ncs_model_details +_refine_ls_restr_ncs.rms_dev_B_iso +_refine_ls_restr_ncs.weight_B_iso +1 A 14054 0.07 0.05 'interatomic distance' 1 1 'X-RAY DIFFRACTION' ? ? ? +2 B 14054 0.07 0.05 'interatomic distance' 1 2 'X-RAY DIFFRACTION' ? ? ? +1 A 14007 0.07 0.05 'interatomic distance' 2 3 'X-RAY DIFFRACTION' ? ? ? +2 C 14007 0.07 0.05 'interatomic distance' 2 4 'X-RAY DIFFRACTION' ? ? ? +1 A 13844 0.08 0.05 'interatomic distance' 3 5 'X-RAY DIFFRACTION' ? ? ? +2 D 13844 0.08 0.05 'interatomic distance' 3 6 'X-RAY DIFFRACTION' ? ? ? +1 A 13795 0.08 0.05 'interatomic distance' 4 7 'X-RAY DIFFRACTION' ? ? ? +2 E 13795 0.08 0.05 'interatomic distance' 4 8 'X-RAY DIFFRACTION' ? ? ? +1 A 13886 0.07 0.05 'interatomic distance' 5 9 'X-RAY DIFFRACTION' ? ? ? +2 F 13886 0.07 0.05 'interatomic distance' 5 10 'X-RAY DIFFRACTION' ? ? ? +1 A 13831 0.08 0.05 'interatomic distance' 6 11 'X-RAY DIFFRACTION' ? ? ? +2 G 13831 0.08 0.05 'interatomic distance' 6 12 'X-RAY DIFFRACTION' ? ? ? +1 A 14063 0.07 0.05 'interatomic distance' 7 13 'X-RAY DIFFRACTION' ? ? ? +2 H 14063 0.07 0.05 'interatomic distance' 7 14 'X-RAY DIFFRACTION' ? ? ? +1 A 13947 0.07 0.05 'interatomic distance' 8 15 'X-RAY DIFFRACTION' ? ? ? +2 I 13947 0.07 0.05 'interatomic distance' 8 16 'X-RAY DIFFRACTION' ? ? ? +1 A 14013 0.08 0.05 'interatomic distance' 9 17 'X-RAY DIFFRACTION' ? ? ? +2 J 14013 0.08 0.05 'interatomic distance' 9 18 'X-RAY DIFFRACTION' ? ? ? +1 A 13954 0.07 0.05 'interatomic distance' 10 19 'X-RAY DIFFRACTION' ? ? ? +2 K 13954 0.07 0.05 'interatomic distance' 10 20 'X-RAY DIFFRACTION' ? ? ? +1 A 14151 0.06 0.05 'interatomic distance' 11 21 'X-RAY DIFFRACTION' ? ? ? +2 L 14151 0.06 0.05 'interatomic distance' 11 22 'X-RAY DIFFRACTION' ? ? ? +1 A 13857 0.08 0.05 'interatomic distance' 12 23 'X-RAY DIFFRACTION' ? ? ? +2 M 13857 0.08 0.05 'interatomic distance' 12 24 'X-RAY DIFFRACTION' ? ? ? +1 A 13997 0.08 0.05 'interatomic distance' 13 25 'X-RAY DIFFRACTION' ? ? ? +2 N 13997 0.08 0.05 'interatomic distance' 13 26 'X-RAY DIFFRACTION' ? ? ? +1 A 13817 0.08 0.05 'interatomic distance' 14 27 'X-RAY DIFFRACTION' ? ? ? +2 O 13817 0.08 0.05 'interatomic distance' 14 28 'X-RAY DIFFRACTION' ? ? ? +1 A 13844 0.08 0.05 'interatomic distance' 15 29 'X-RAY DIFFRACTION' ? ? ? +2 P 13844 0.08 0.05 'interatomic distance' 15 30 'X-RAY DIFFRACTION' ? ? ? +1 A 13849 0.08 0.05 'interatomic distance' 16 31 'X-RAY DIFFRACTION' ? ? ? +2 Q 13849 0.08 0.05 'interatomic distance' 16 32 'X-RAY DIFFRACTION' ? ? ? +1 A 13843 0.09 0.05 'interatomic distance' 17 33 'X-RAY DIFFRACTION' ? ? ? +2 R 13843 0.09 0.05 'interatomic distance' 17 34 'X-RAY DIFFRACTION' ? ? ? +1 B 14086 0.06 0.05 'interatomic distance' 18 35 'X-RAY DIFFRACTION' ? ? ? +2 C 14086 0.06 0.05 'interatomic distance' 18 36 'X-RAY DIFFRACTION' ? ? ? +1 B 14006 0.08 0.05 'interatomic distance' 19 37 'X-RAY DIFFRACTION' ? ? ? +2 D 14006 0.08 0.05 'interatomic distance' 19 38 'X-RAY DIFFRACTION' ? ? ? +1 B 13875 0.08 0.05 'interatomic distance' 20 39 'X-RAY DIFFRACTION' ? ? ? +2 E 13875 0.08 0.05 'interatomic distance' 20 40 'X-RAY DIFFRACTION' ? ? ? +1 B 13994 0.07 0.05 'interatomic distance' 21 41 'X-RAY DIFFRACTION' ? ? ? +2 F 13994 0.07 0.05 'interatomic distance' 21 42 'X-RAY DIFFRACTION' ? ? ? +1 B 13845 0.08 0.05 'interatomic distance' 22 43 'X-RAY DIFFRACTION' ? ? ? +2 G 13845 0.08 0.05 'interatomic distance' 22 44 'X-RAY DIFFRACTION' ? ? ? +1 B 14047 0.07 0.05 'interatomic distance' 23 45 'X-RAY DIFFRACTION' ? ? ? +2 H 14047 0.07 0.05 'interatomic distance' 23 46 'X-RAY DIFFRACTION' ? ? ? +1 B 14135 0.07 0.05 'interatomic distance' 24 47 'X-RAY DIFFRACTION' ? ? ? +2 I 14135 0.07 0.05 'interatomic distance' 24 48 'X-RAY DIFFRACTION' ? ? ? +1 B 14092 0.07 0.05 'interatomic distance' 25 49 'X-RAY DIFFRACTION' ? ? ? +2 J 14092 0.07 0.05 'interatomic distance' 25 50 'X-RAY DIFFRACTION' ? ? ? +1 B 14040 0.07 0.05 'interatomic distance' 26 51 'X-RAY DIFFRACTION' ? ? ? +2 K 14040 0.07 0.05 'interatomic distance' 26 52 'X-RAY DIFFRACTION' ? ? ? +1 B 14036 0.07 0.05 'interatomic distance' 27 53 'X-RAY DIFFRACTION' ? ? ? +2 L 14036 0.07 0.05 'interatomic distance' 27 54 'X-RAY DIFFRACTION' ? ? ? +1 B 13980 0.07 0.05 'interatomic distance' 28 55 'X-RAY DIFFRACTION' ? ? ? +2 M 13980 0.07 0.05 'interatomic distance' 28 56 'X-RAY DIFFRACTION' ? ? ? +1 B 14028 0.07 0.05 'interatomic distance' 29 57 'X-RAY DIFFRACTION' ? ? ? +2 N 14028 0.07 0.05 'interatomic distance' 29 58 'X-RAY DIFFRACTION' ? ? ? +1 B 13966 0.07 0.05 'interatomic distance' 30 59 'X-RAY DIFFRACTION' ? ? ? +2 O 13966 0.07 0.05 'interatomic distance' 30 60 'X-RAY DIFFRACTION' ? ? ? +1 B 13990 0.08 0.05 'interatomic distance' 31 61 'X-RAY DIFFRACTION' ? ? ? +2 P 13990 0.08 0.05 'interatomic distance' 31 62 'X-RAY DIFFRACTION' ? ? ? +1 B 13982 0.07 0.05 'interatomic distance' 32 63 'X-RAY DIFFRACTION' ? ? ? +2 Q 13982 0.07 0.05 'interatomic distance' 32 64 'X-RAY DIFFRACTION' ? ? ? +1 B 13879 0.09 0.05 'interatomic distance' 33 65 'X-RAY DIFFRACTION' ? ? ? +2 R 13879 0.09 0.05 'interatomic distance' 33 66 'X-RAY DIFFRACTION' ? ? ? +1 C 14026 0.07 0.05 'interatomic distance' 34 67 'X-RAY DIFFRACTION' ? ? ? +2 D 14026 0.07 0.05 'interatomic distance' 34 68 'X-RAY DIFFRACTION' ? ? ? +1 C 13979 0.08 0.05 'interatomic distance' 35 69 'X-RAY DIFFRACTION' ? ? ? +2 E 13979 0.08 0.05 'interatomic distance' 35 70 'X-RAY DIFFRACTION' ? ? ? +1 C 14085 0.06 0.05 'interatomic distance' 36 71 'X-RAY DIFFRACTION' ? ? ? +2 F 14085 0.06 0.05 'interatomic distance' 36 72 'X-RAY DIFFRACTION' ? ? ? +1 C 14041 0.07 0.05 'interatomic distance' 37 73 'X-RAY DIFFRACTION' ? ? ? +2 G 14041 0.07 0.05 'interatomic distance' 37 74 'X-RAY DIFFRACTION' ? ? ? +1 C 14152 0.06 0.05 'interatomic distance' 38 75 'X-RAY DIFFRACTION' ? ? ? +2 H 14152 0.06 0.05 'interatomic distance' 38 76 'X-RAY DIFFRACTION' ? ? ? +1 C 14157 0.07 0.05 'interatomic distance' 39 77 'X-RAY DIFFRACTION' ? ? ? +2 I 14157 0.07 0.05 'interatomic distance' 39 78 'X-RAY DIFFRACTION' ? ? ? +1 C 14138 0.06 0.05 'interatomic distance' 40 79 'X-RAY DIFFRACTION' ? ? ? +2 J 14138 0.06 0.05 'interatomic distance' 40 80 'X-RAY DIFFRACTION' ? ? ? +1 C 14157 0.06 0.05 'interatomic distance' 41 81 'X-RAY DIFFRACTION' ? ? ? +2 K 14157 0.06 0.05 'interatomic distance' 41 82 'X-RAY DIFFRACTION' ? ? ? +1 C 14096 0.07 0.05 'interatomic distance' 42 83 'X-RAY DIFFRACTION' ? ? ? +2 L 14096 0.07 0.05 'interatomic distance' 42 84 'X-RAY DIFFRACTION' ? ? ? +1 C 14070 0.07 0.05 'interatomic distance' 43 85 'X-RAY DIFFRACTION' ? ? ? +2 M 14070 0.07 0.05 'interatomic distance' 43 86 'X-RAY DIFFRACTION' ? ? ? +1 C 14224 0.06 0.05 'interatomic distance' 44 87 'X-RAY DIFFRACTION' ? ? ? +2 N 14224 0.06 0.05 'interatomic distance' 44 88 'X-RAY DIFFRACTION' ? ? ? +1 C 14031 0.07 0.05 'interatomic distance' 45 89 'X-RAY DIFFRACTION' ? ? ? +2 O 14031 0.07 0.05 'interatomic distance' 45 90 'X-RAY DIFFRACTION' ? ? ? +1 C 14082 0.07 0.05 'interatomic distance' 46 91 'X-RAY DIFFRACTION' ? ? ? +2 P 14082 0.07 0.05 'interatomic distance' 46 92 'X-RAY DIFFRACTION' ? ? ? +1 C 14127 0.06 0.05 'interatomic distance' 47 93 'X-RAY DIFFRACTION' ? ? ? +2 Q 14127 0.06 0.05 'interatomic distance' 47 94 'X-RAY DIFFRACTION' ? ? ? +1 C 13982 0.08 0.05 'interatomic distance' 48 95 'X-RAY DIFFRACTION' ? ? ? +2 R 13982 0.08 0.05 'interatomic distance' 48 96 'X-RAY DIFFRACTION' ? ? ? +1 D 13984 0.07 0.05 'interatomic distance' 49 97 'X-RAY DIFFRACTION' ? ? ? +2 E 13984 0.07 0.05 'interatomic distance' 49 98 'X-RAY DIFFRACTION' ? ? ? +1 D 14083 0.06 0.05 'interatomic distance' 50 99 'X-RAY DIFFRACTION' ? ? ? +2 F 14083 0.06 0.05 'interatomic distance' 50 100 'X-RAY DIFFRACTION' ? ? ? +1 D 14089 0.06 0.05 'interatomic distance' 51 101 'X-RAY DIFFRACTION' ? ? ? +2 G 14089 0.06 0.05 'interatomic distance' 51 102 'X-RAY DIFFRACTION' ? ? ? +1 D 14150 0.06 0.05 'interatomic distance' 52 103 'X-RAY DIFFRACTION' ? ? ? +2 H 14150 0.06 0.05 'interatomic distance' 52 104 'X-RAY DIFFRACTION' ? ? ? +1 D 14152 0.06 0.05 'interatomic distance' 53 105 'X-RAY DIFFRACTION' ? ? ? +2 I 14152 0.06 0.05 'interatomic distance' 53 106 'X-RAY DIFFRACTION' ? ? ? +1 D 14146 0.06 0.05 'interatomic distance' 54 107 'X-RAY DIFFRACTION' ? ? ? +2 J 14146 0.06 0.05 'interatomic distance' 54 108 'X-RAY DIFFRACTION' ? ? ? +1 D 14113 0.05 0.05 'interatomic distance' 55 109 'X-RAY DIFFRACTION' ? ? ? +2 K 14113 0.05 0.05 'interatomic distance' 55 110 'X-RAY DIFFRACTION' ? ? ? +1 D 13996 0.07 0.05 'interatomic distance' 56 111 'X-RAY DIFFRACTION' ? ? ? +2 L 13996 0.07 0.05 'interatomic distance' 56 112 'X-RAY DIFFRACTION' ? ? ? +1 D 14056 0.06 0.05 'interatomic distance' 57 113 'X-RAY DIFFRACTION' ? ? ? +2 M 14056 0.06 0.05 'interatomic distance' 57 114 'X-RAY DIFFRACTION' ? ? ? +1 D 14079 0.06 0.05 'interatomic distance' 58 115 'X-RAY DIFFRACTION' ? ? ? +2 N 14079 0.06 0.05 'interatomic distance' 58 116 'X-RAY DIFFRACTION' ? ? ? +1 D 14236 0.04 0.05 'interatomic distance' 59 117 'X-RAY DIFFRACTION' ? ? ? +2 O 14236 0.04 0.05 'interatomic distance' 59 118 'X-RAY DIFFRACTION' ? ? ? +1 D 14060 0.06 0.05 'interatomic distance' 60 119 'X-RAY DIFFRACTION' ? ? ? +2 P 14060 0.06 0.05 'interatomic distance' 60 120 'X-RAY DIFFRACTION' ? ? ? +1 D 14090 0.06 0.05 'interatomic distance' 61 121 'X-RAY DIFFRACTION' ? ? ? +2 Q 14090 0.06 0.05 'interatomic distance' 61 122 'X-RAY DIFFRACTION' ? ? ? +1 D 13893 0.08 0.05 'interatomic distance' 62 123 'X-RAY DIFFRACTION' ? ? ? +2 R 13893 0.08 0.05 'interatomic distance' 62 124 'X-RAY DIFFRACTION' ? ? ? +1 E 14015 0.07 0.05 'interatomic distance' 63 125 'X-RAY DIFFRACTION' ? ? ? +2 F 14015 0.07 0.05 'interatomic distance' 63 126 'X-RAY DIFFRACTION' ? ? ? +1 E 13918 0.08 0.05 'interatomic distance' 64 127 'X-RAY DIFFRACTION' ? ? ? +2 G 13918 0.08 0.05 'interatomic distance' 64 128 'X-RAY DIFFRACTION' ? ? ? +1 E 14029 0.07 0.05 'interatomic distance' 65 129 'X-RAY DIFFRACTION' ? ? ? +2 H 14029 0.07 0.05 'interatomic distance' 65 130 'X-RAY DIFFRACTION' ? ? ? +1 E 14091 0.07 0.05 'interatomic distance' 66 131 'X-RAY DIFFRACTION' ? ? ? +2 I 14091 0.07 0.05 'interatomic distance' 66 132 'X-RAY DIFFRACTION' ? ? ? +1 E 13966 0.08 0.05 'interatomic distance' 67 133 'X-RAY DIFFRACTION' ? ? ? +2 J 13966 0.08 0.05 'interatomic distance' 67 134 'X-RAY DIFFRACTION' ? ? ? +1 E 14010 0.07 0.05 'interatomic distance' 68 135 'X-RAY DIFFRACTION' ? ? ? +2 K 14010 0.07 0.05 'interatomic distance' 68 136 'X-RAY DIFFRACTION' ? ? ? +1 E 13962 0.08 0.05 'interatomic distance' 69 137 'X-RAY DIFFRACTION' ? ? ? +2 L 13962 0.08 0.05 'interatomic distance' 69 138 'X-RAY DIFFRACTION' ? ? ? +1 E 13976 0.08 0.05 'interatomic distance' 70 139 'X-RAY DIFFRACTION' ? ? ? +2 M 13976 0.08 0.05 'interatomic distance' 70 140 'X-RAY DIFFRACTION' ? ? ? +1 E 13974 0.08 0.05 'interatomic distance' 71 141 'X-RAY DIFFRACTION' ? ? ? +2 N 13974 0.08 0.05 'interatomic distance' 71 142 'X-RAY DIFFRACTION' ? ? ? +1 E 13991 0.07 0.05 'interatomic distance' 72 143 'X-RAY DIFFRACTION' ? ? ? +2 O 13991 0.07 0.05 'interatomic distance' 72 144 'X-RAY DIFFRACTION' ? ? ? +1 E 14014 0.08 0.05 'interatomic distance' 73 145 'X-RAY DIFFRACTION' ? ? ? +2 P 14014 0.08 0.05 'interatomic distance' 73 146 'X-RAY DIFFRACTION' ? ? ? +1 E 14012 0.08 0.05 'interatomic distance' 74 147 'X-RAY DIFFRACTION' ? ? ? +2 Q 14012 0.08 0.05 'interatomic distance' 74 148 'X-RAY DIFFRACTION' ? ? ? +1 E 13893 0.09 0.05 'interatomic distance' 75 149 'X-RAY DIFFRACTION' ? ? ? +2 R 13893 0.09 0.05 'interatomic distance' 75 150 'X-RAY DIFFRACTION' ? ? ? +1 F 14018 0.07 0.05 'interatomic distance' 76 151 'X-RAY DIFFRACTION' ? ? ? +2 G 14018 0.07 0.05 'interatomic distance' 76 152 'X-RAY DIFFRACTION' ? ? ? +1 F 14125 0.05 0.05 'interatomic distance' 77 153 'X-RAY DIFFRACTION' ? ? ? +2 H 14125 0.05 0.05 'interatomic distance' 77 154 'X-RAY DIFFRACTION' ? ? ? +1 F 14187 0.05 0.05 'interatomic distance' 78 155 'X-RAY DIFFRACTION' ? ? ? +2 I 14187 0.05 0.05 'interatomic distance' 78 156 'X-RAY DIFFRACTION' ? ? ? +1 F 14138 0.05 0.05 'interatomic distance' 79 157 'X-RAY DIFFRACTION' ? ? ? +2 J 14138 0.05 0.05 'interatomic distance' 79 158 'X-RAY DIFFRACTION' ? ? ? +1 F 14148 0.05 0.05 'interatomic distance' 80 159 'X-RAY DIFFRACTION' ? ? ? +2 K 14148 0.05 0.05 'interatomic distance' 80 160 'X-RAY DIFFRACTION' ? ? ? +1 F 14119 0.06 0.05 'interatomic distance' 81 161 'X-RAY DIFFRACTION' ? ? ? +2 L 14119 0.06 0.05 'interatomic distance' 81 162 'X-RAY DIFFRACTION' ? ? ? +1 F 14110 0.06 0.05 'interatomic distance' 82 163 'X-RAY DIFFRACTION' ? ? ? +2 M 14110 0.06 0.05 'interatomic distance' 82 164 'X-RAY DIFFRACTION' ? ? ? +1 F 14137 0.06 0.05 'interatomic distance' 83 165 'X-RAY DIFFRACTION' ? ? ? +2 N 14137 0.06 0.05 'interatomic distance' 83 166 'X-RAY DIFFRACTION' ? ? ? +1 F 14100 0.06 0.05 'interatomic distance' 84 167 'X-RAY DIFFRACTION' ? ? ? +2 O 14100 0.06 0.05 'interatomic distance' 84 168 'X-RAY DIFFRACTION' ? ? ? +1 F 14130 0.06 0.05 'interatomic distance' 85 169 'X-RAY DIFFRACTION' ? ? ? +2 P 14130 0.06 0.05 'interatomic distance' 85 170 'X-RAY DIFFRACTION' ? ? ? +1 F 14256 0.05 0.05 'interatomic distance' 86 171 'X-RAY DIFFRACTION' ? ? ? +2 Q 14256 0.05 0.05 'interatomic distance' 86 172 'X-RAY DIFFRACTION' ? ? ? +1 F 13980 0.07 0.05 'interatomic distance' 87 173 'X-RAY DIFFRACTION' ? ? ? +2 R 13980 0.07 0.05 'interatomic distance' 87 174 'X-RAY DIFFRACTION' ? ? ? +1 G 14123 0.06 0.05 'interatomic distance' 88 175 'X-RAY DIFFRACTION' ? ? ? +2 H 14123 0.06 0.05 'interatomic distance' 88 176 'X-RAY DIFFRACTION' ? ? ? +1 G 14097 0.06 0.05 'interatomic distance' 89 177 'X-RAY DIFFRACTION' ? ? ? +2 I 14097 0.06 0.05 'interatomic distance' 89 178 'X-RAY DIFFRACTION' ? ? ? +1 G 14111 0.06 0.05 'interatomic distance' 90 179 'X-RAY DIFFRACTION' ? ? ? +2 J 14111 0.06 0.05 'interatomic distance' 90 180 'X-RAY DIFFRACTION' ? ? ? +1 G 14134 0.06 0.05 'interatomic distance' 91 181 'X-RAY DIFFRACTION' ? ? ? +2 K 14134 0.06 0.05 'interatomic distance' 91 182 'X-RAY DIFFRACTION' ? ? ? +1 G 13951 0.07 0.05 'interatomic distance' 92 183 'X-RAY DIFFRACTION' ? ? ? +2 L 13951 0.07 0.05 'interatomic distance' 92 184 'X-RAY DIFFRACTION' ? ? ? +1 G 13960 0.07 0.05 'interatomic distance' 93 185 'X-RAY DIFFRACTION' ? ? ? +2 M 13960 0.07 0.05 'interatomic distance' 93 186 'X-RAY DIFFRACTION' ? ? ? +1 G 14068 0.07 0.05 'interatomic distance' 94 187 'X-RAY DIFFRACTION' ? ? ? +2 N 14068 0.07 0.05 'interatomic distance' 94 188 'X-RAY DIFFRACTION' ? ? ? +1 G 14070 0.07 0.05 'interatomic distance' 95 189 'X-RAY DIFFRACTION' ? ? ? +2 O 14070 0.07 0.05 'interatomic distance' 95 190 'X-RAY DIFFRACTION' ? ? ? +1 G 14026 0.07 0.05 'interatomic distance' 96 191 'X-RAY DIFFRACTION' ? ? ? +2 P 14026 0.07 0.05 'interatomic distance' 96 192 'X-RAY DIFFRACTION' ? ? ? +1 G 14026 0.07 0.05 'interatomic distance' 97 193 'X-RAY DIFFRACTION' ? ? ? +2 Q 14026 0.07 0.05 'interatomic distance' 97 194 'X-RAY DIFFRACTION' ? ? ? +1 G 14072 0.07 0.05 'interatomic distance' 98 195 'X-RAY DIFFRACTION' ? ? ? +2 R 14072 0.07 0.05 'interatomic distance' 98 196 'X-RAY DIFFRACTION' ? ? ? +1 H 14223 0.06 0.05 'interatomic distance' 99 197 'X-RAY DIFFRACTION' ? ? ? +2 I 14223 0.06 0.05 'interatomic distance' 99 198 'X-RAY DIFFRACTION' ? ? ? +1 H 14384 0.05 0.05 'interatomic distance' 100 199 'X-RAY DIFFRACTION' ? ? ? +2 J 14384 0.05 0.05 'interatomic distance' 100 200 'X-RAY DIFFRACTION' ? ? ? +1 H 14322 0.05 0.05 'interatomic distance' 101 201 'X-RAY DIFFRACTION' ? ? ? +2 K 14322 0.05 0.05 'interatomic distance' 101 202 'X-RAY DIFFRACTION' ? ? ? +1 H 14077 0.06 0.05 'interatomic distance' 102 203 'X-RAY DIFFRACTION' ? ? ? +2 L 14077 0.06 0.05 'interatomic distance' 102 204 'X-RAY DIFFRACTION' ? ? ? +1 H 14095 0.06 0.05 'interatomic distance' 103 205 'X-RAY DIFFRACTION' ? ? ? +2 M 14095 0.06 0.05 'interatomic distance' 103 206 'X-RAY DIFFRACTION' ? ? ? +1 H 14233 0.06 0.05 'interatomic distance' 104 207 'X-RAY DIFFRACTION' ? ? ? +2 N 14233 0.06 0.05 'interatomic distance' 104 208 'X-RAY DIFFRACTION' ? ? ? +1 H 14090 0.06 0.05 'interatomic distance' 105 209 'X-RAY DIFFRACTION' ? ? ? +2 O 14090 0.06 0.05 'interatomic distance' 105 210 'X-RAY DIFFRACTION' ? ? ? +1 H 14099 0.07 0.05 'interatomic distance' 106 211 'X-RAY DIFFRACTION' ? ? ? +2 P 14099 0.07 0.05 'interatomic distance' 106 212 'X-RAY DIFFRACTION' ? ? ? +1 H 14125 0.06 0.05 'interatomic distance' 107 213 'X-RAY DIFFRACTION' ? ? ? +2 Q 14125 0.06 0.05 'interatomic distance' 107 214 'X-RAY DIFFRACTION' ? ? ? +1 H 14070 0.07 0.05 'interatomic distance' 108 215 'X-RAY DIFFRACTION' ? ? ? +2 R 14070 0.07 0.05 'interatomic distance' 108 216 'X-RAY DIFFRACTION' ? ? ? +1 I 14261 0.05 0.05 'interatomic distance' 109 217 'X-RAY DIFFRACTION' ? ? ? +2 J 14261 0.05 0.05 'interatomic distance' 109 218 'X-RAY DIFFRACTION' ? ? ? +1 I 14313 0.05 0.05 'interatomic distance' 110 219 'X-RAY DIFFRACTION' ? ? ? +2 K 14313 0.05 0.05 'interatomic distance' 110 220 'X-RAY DIFFRACTION' ? ? ? +1 I 14106 0.07 0.05 'interatomic distance' 111 221 'X-RAY DIFFRACTION' ? ? ? +2 L 14106 0.07 0.05 'interatomic distance' 111 222 'X-RAY DIFFRACTION' ? ? ? +1 I 14145 0.06 0.05 'interatomic distance' 112 223 'X-RAY DIFFRACTION' ? ? ? +2 M 14145 0.06 0.05 'interatomic distance' 112 224 'X-RAY DIFFRACTION' ? ? ? +1 I 14170 0.06 0.05 'interatomic distance' 113 225 'X-RAY DIFFRACTION' ? ? ? +2 N 14170 0.06 0.05 'interatomic distance' 113 226 'X-RAY DIFFRACTION' ? ? ? +1 I 14123 0.06 0.05 'interatomic distance' 114 227 'X-RAY DIFFRACTION' ? ? ? +2 O 14123 0.06 0.05 'interatomic distance' 114 228 'X-RAY DIFFRACTION' ? ? ? +1 I 14171 0.06 0.05 'interatomic distance' 115 229 'X-RAY DIFFRACTION' ? ? ? +2 P 14171 0.06 0.05 'interatomic distance' 115 230 'X-RAY DIFFRACTION' ? ? ? +1 I 14206 0.06 0.05 'interatomic distance' 116 231 'X-RAY DIFFRACTION' ? ? ? +2 Q 14206 0.06 0.05 'interatomic distance' 116 232 'X-RAY DIFFRACTION' ? ? ? +1 I 14079 0.07 0.05 'interatomic distance' 117 233 'X-RAY DIFFRACTION' ? ? ? +2 R 14079 0.07 0.05 'interatomic distance' 117 234 'X-RAY DIFFRACTION' ? ? ? +1 J 14399 0.03 0.05 'interatomic distance' 118 235 'X-RAY DIFFRACTION' ? ? ? +2 K 14399 0.03 0.05 'interatomic distance' 118 236 'X-RAY DIFFRACTION' ? ? ? +1 J 14049 0.07 0.05 'interatomic distance' 119 237 'X-RAY DIFFRACTION' ? ? ? +2 L 14049 0.07 0.05 'interatomic distance' 119 238 'X-RAY DIFFRACTION' ? ? ? +1 J 14098 0.06 0.05 'interatomic distance' 120 239 'X-RAY DIFFRACTION' ? ? ? +2 M 14098 0.06 0.05 'interatomic distance' 120 240 'X-RAY DIFFRACTION' ? ? ? +1 J 14205 0.06 0.05 'interatomic distance' 121 241 'X-RAY DIFFRACTION' ? ? ? +2 N 14205 0.06 0.05 'interatomic distance' 121 242 'X-RAY DIFFRACTION' ? ? ? +1 J 14044 0.06 0.05 'interatomic distance' 122 243 'X-RAY DIFFRACTION' ? ? ? +2 O 14044 0.06 0.05 'interatomic distance' 122 244 'X-RAY DIFFRACTION' ? ? ? +1 J 14098 0.06 0.05 'interatomic distance' 123 245 'X-RAY DIFFRACTION' ? ? ? +2 P 14098 0.06 0.05 'interatomic distance' 123 246 'X-RAY DIFFRACTION' ? ? ? +1 J 14149 0.05 0.05 'interatomic distance' 124 247 'X-RAY DIFFRACTION' ? ? ? +2 Q 14149 0.05 0.05 'interatomic distance' 124 248 'X-RAY DIFFRACTION' ? ? ? +1 J 14109 0.07 0.05 'interatomic distance' 125 249 'X-RAY DIFFRACTION' ? ? ? +2 R 14109 0.07 0.05 'interatomic distance' 125 250 'X-RAY DIFFRACTION' ? ? ? +1 K 14082 0.06 0.05 'interatomic distance' 126 251 'X-RAY DIFFRACTION' ? ? ? +2 L 14082 0.06 0.05 'interatomic distance' 126 252 'X-RAY DIFFRACTION' ? ? ? +1 K 14100 0.06 0.05 'interatomic distance' 127 253 'X-RAY DIFFRACTION' ? ? ? +2 M 14100 0.06 0.05 'interatomic distance' 127 254 'X-RAY DIFFRACTION' ? ? ? +1 K 14240 0.06 0.05 'interatomic distance' 128 255 'X-RAY DIFFRACTION' ? ? ? +2 N 14240 0.06 0.05 'interatomic distance' 128 256 'X-RAY DIFFRACTION' ? ? ? +1 K 14079 0.06 0.05 'interatomic distance' 129 257 'X-RAY DIFFRACTION' ? ? ? +2 O 14079 0.06 0.05 'interatomic distance' 129 258 'X-RAY DIFFRACTION' ? ? ? +1 K 14100 0.06 0.05 'interatomic distance' 130 259 'X-RAY DIFFRACTION' ? ? ? +2 P 14100 0.06 0.05 'interatomic distance' 130 260 'X-RAY DIFFRACTION' ? ? ? +1 K 14154 0.06 0.05 'interatomic distance' 131 261 'X-RAY DIFFRACTION' ? ? ? +2 Q 14154 0.06 0.05 'interatomic distance' 131 262 'X-RAY DIFFRACTION' ? ? ? +1 K 14134 0.07 0.05 'interatomic distance' 132 263 'X-RAY DIFFRACTION' ? ? ? +2 R 14134 0.07 0.05 'interatomic distance' 132 264 'X-RAY DIFFRACTION' ? ? ? +1 L 14102 0.07 0.05 'interatomic distance' 133 265 'X-RAY DIFFRACTION' ? ? ? +2 M 14102 0.07 0.05 'interatomic distance' 133 266 'X-RAY DIFFRACTION' ? ? ? +1 L 14058 0.07 0.05 'interatomic distance' 134 267 'X-RAY DIFFRACTION' ? ? ? +2 N 14058 0.07 0.05 'interatomic distance' 134 268 'X-RAY DIFFRACTION' ? ? ? +1 L 14060 0.06 0.05 'interatomic distance' 135 269 'X-RAY DIFFRACTION' ? ? ? +2 O 14060 0.06 0.05 'interatomic distance' 135 270 'X-RAY DIFFRACTION' ? ? ? +1 L 14096 0.06 0.05 'interatomic distance' 136 271 'X-RAY DIFFRACTION' ? ? ? +2 P 14096 0.06 0.05 'interatomic distance' 136 272 'X-RAY DIFFRACTION' ? ? ? +1 L 14091 0.07 0.05 'interatomic distance' 137 273 'X-RAY DIFFRACTION' ? ? ? +2 Q 14091 0.07 0.05 'interatomic distance' 137 274 'X-RAY DIFFRACTION' ? ? ? +1 L 13900 0.08 0.05 'interatomic distance' 138 275 'X-RAY DIFFRACTION' ? ? ? +2 R 13900 0.08 0.05 'interatomic distance' 138 276 'X-RAY DIFFRACTION' ? ? ? +1 M 14102 0.06 0.05 'interatomic distance' 139 277 'X-RAY DIFFRACTION' ? ? ? +2 N 14102 0.06 0.05 'interatomic distance' 139 278 'X-RAY DIFFRACTION' ? ? ? +1 M 14197 0.05 0.05 'interatomic distance' 140 279 'X-RAY DIFFRACTION' ? ? ? +2 O 14197 0.05 0.05 'interatomic distance' 140 280 'X-RAY DIFFRACTION' ? ? ? +1 M 14217 0.06 0.05 'interatomic distance' 141 281 'X-RAY DIFFRACTION' ? ? ? +2 P 14217 0.06 0.05 'interatomic distance' 141 282 'X-RAY DIFFRACTION' ? ? ? +1 M 14295 0.05 0.05 'interatomic distance' 142 283 'X-RAY DIFFRACTION' ? ? ? +2 Q 14295 0.05 0.05 'interatomic distance' 142 284 'X-RAY DIFFRACTION' ? ? ? +1 M 14055 0.07 0.05 'interatomic distance' 143 285 'X-RAY DIFFRACTION' ? ? ? +2 R 14055 0.07 0.05 'interatomic distance' 143 286 'X-RAY DIFFRACTION' ? ? ? +1 N 14116 0.06 0.05 'interatomic distance' 144 287 'X-RAY DIFFRACTION' ? ? ? +2 O 14116 0.06 0.05 'interatomic distance' 144 288 'X-RAY DIFFRACTION' ? ? ? +1 N 14071 0.07 0.05 'interatomic distance' 145 289 'X-RAY DIFFRACTION' ? ? ? +2 P 14071 0.07 0.05 'interatomic distance' 145 290 'X-RAY DIFFRACTION' ? ? ? +1 N 14145 0.06 0.05 'interatomic distance' 146 291 'X-RAY DIFFRACTION' ? ? ? +2 Q 14145 0.06 0.05 'interatomic distance' 146 292 'X-RAY DIFFRACTION' ? ? ? +1 N 14069 0.08 0.05 'interatomic distance' 147 293 'X-RAY DIFFRACTION' ? ? ? +2 R 14069 0.08 0.05 'interatomic distance' 147 294 'X-RAY DIFFRACTION' ? ? ? +1 O 14245 0.05 0.05 'interatomic distance' 148 295 'X-RAY DIFFRACTION' ? ? ? +2 P 14245 0.05 0.05 'interatomic distance' 148 296 'X-RAY DIFFRACTION' ? ? ? +1 O 14253 0.05 0.05 'interatomic distance' 149 297 'X-RAY DIFFRACTION' ? ? ? +2 Q 14253 0.05 0.05 'interatomic distance' 149 298 'X-RAY DIFFRACTION' ? ? ? +1 O 14058 0.07 0.05 'interatomic distance' 150 299 'X-RAY DIFFRACTION' ? ? ? +2 R 14058 0.07 0.05 'interatomic distance' 150 300 'X-RAY DIFFRACTION' ? ? ? +1 P 14276 0.05 0.05 'interatomic distance' 151 301 'X-RAY DIFFRACTION' ? ? ? +2 Q 14276 0.05 0.05 'interatomic distance' 151 302 'X-RAY DIFFRACTION' ? ? ? +1 P 14050 0.08 0.05 'interatomic distance' 152 303 'X-RAY DIFFRACTION' ? ? ? +2 R 14050 0.08 0.05 'interatomic distance' 152 304 'X-RAY DIFFRACTION' ? ? ? +1 Q 14139 0.07 0.05 'interatomic distance' 153 305 'X-RAY DIFFRACTION' ? ? ? +2 R 14139 0.07 0.05 'interatomic distance' 153 306 'X-RAY DIFFRACTION' ? ? ? +# +_refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' +_refine_ls_shell.pdbx_total_number_of_bins_used 20 +_refine_ls_shell.d_res_high 3.587 +_refine_ls_shell.d_res_low 3.680 +_refine_ls_shell.number_reflns_R_work 1429 +_refine_ls_shell.R_factor_R_work 0.334 +_refine_ls_shell.percent_reflns_obs 18.18 +_refine_ls_shell.R_factor_R_free 0.403 +_refine_ls_shell.R_factor_R_free_error ? +_refine_ls_shell.percent_reflns_R_free ? +_refine_ls_shell.number_reflns_R_free 75 +_refine_ls_shell.number_reflns_all ? +_refine_ls_shell.R_factor_all ? +# +loop_ +_struct_ncs_oper.id +_struct_ncs_oper.code +_struct_ncs_oper.details +_struct_ncs_oper.matrix[1][1] +_struct_ncs_oper.matrix[1][2] +_struct_ncs_oper.matrix[1][3] +_struct_ncs_oper.matrix[2][1] +_struct_ncs_oper.matrix[2][2] +_struct_ncs_oper.matrix[2][3] +_struct_ncs_oper.matrix[3][1] +_struct_ncs_oper.matrix[3][2] +_struct_ncs_oper.matrix[3][3] +_struct_ncs_oper.vector[1] +_struct_ncs_oper.vector[2] +_struct_ncs_oper.vector[3] +1 given ? 0.762000 0.010000 0.648000 -0.012000 1.000000 -0.002000 -0.648000 -0.006000 0.762000 -17.50403 0.41453 34.08517 +2 given ? 0.168000 0.008000 0.986000 -0.016000 1.000000 -0.006000 -0.986000 -0.014000 0.168000 -9.23430 0.73640 71.23841 +3 given ? -0.503000 0.000000 0.864000 -0.022000 1.000000 -0.013000 -0.864000 -0.025000 -0.503000 20.88865 1.24095 94.27494 +4 given ? -0.940000 -0.009000 0.342000 -0.017000 1.000000 -0.020000 -0.342000 -0.025000 -0.939000 58.90655 1.45010 92.72350 +5 given ? -0.938000 -0.015000 -0.345000 -0.007000 1.000000 -0.025000 0.345000 -0.021000 -0.938000 87.07927 1.34548 66.84988 +6 given ? -0.496000 -0.025000 -0.868000 0.000000 1.000000 -0.029000 0.868000 -0.014000 -0.496000 91.79681 1.11549 29.04159 +7 given ? 0.180000 -0.024000 -0.983000 0.001000 1.000000 -0.024000 0.984000 0.004000 0.180000 71.20045 0.79269 -2.83411 +8 given ? 0.769000 -0.013000 -0.639000 0.005000 1.000000 -0.014000 0.639000 0.007000 0.769000 35.00981 0.23753 -14.33744 +9 given ? -0.974000 -0.004000 -0.227000 -0.002000 -1.000000 0.023000 -0.227000 0.023000 0.974000 83.29317 -0.07177 9.79241 +# +loop_ +_struct_ncs_dom.id +_struct_ncs_dom.details +_struct_ncs_dom.pdbx_ens_id +1 A 1 +2 B 1 +1 A 2 +2 C 2 +1 A 3 +2 D 3 +1 A 4 +2 E 4 +1 A 5 +2 F 5 +1 A 6 +2 G 6 +1 A 7 +2 H 7 +1 A 8 +2 I 8 +1 A 9 +2 J 9 +1 A 10 +2 K 10 +1 A 11 +2 L 11 +1 A 12 +2 M 12 +1 A 13 +2 N 13 +1 A 14 +2 O 14 +1 A 15 +2 P 15 +1 A 16 +2 Q 16 +1 A 17 +2 R 17 +1 B 18 +2 C 18 +1 B 19 +2 D 19 +1 B 20 +2 E 20 +1 B 21 +2 F 21 +1 B 22 +2 G 22 +1 B 23 +2 H 23 +1 B 24 +2 I 24 +1 B 25 +2 J 25 +1 B 26 +2 K 26 +1 B 27 +2 L 27 +1 B 28 +2 M 28 +1 B 29 +2 N 29 +1 B 30 +2 O 30 +1 B 31 +2 P 31 +1 B 32 +2 Q 32 +1 B 33 +2 R 33 +1 C 34 +2 D 34 +1 C 35 +2 E 35 +1 C 36 +2 F 36 +1 C 37 +2 G 37 +1 C 38 +2 H 38 +1 C 39 +2 I 39 +1 C 40 +2 J 40 +1 C 41 +2 K 41 +1 C 42 +2 L 42 +1 C 43 +2 M 43 +1 C 44 +2 N 44 +1 C 45 +2 O 45 +1 C 46 +2 P 46 +1 C 47 +2 Q 47 +1 C 48 +2 R 48 +1 D 49 +2 E 49 +1 D 50 +2 F 50 +1 D 51 +2 G 51 +1 D 52 +2 H 52 +1 D 53 +2 I 53 +1 D 54 +2 J 54 +1 D 55 +2 K 55 +1 D 56 +2 L 56 +1 D 57 +2 M 57 +1 D 58 +2 N 58 +1 D 59 +2 O 59 +1 D 60 +2 P 60 +1 D 61 +2 Q 61 +1 D 62 +2 R 62 +1 E 63 +2 F 63 +1 E 64 +2 G 64 +1 E 65 +2 H 65 +1 E 66 +2 I 66 +1 E 67 +2 J 67 +1 E 68 +2 K 68 +1 E 69 +2 L 69 +1 E 70 +2 M 70 +1 E 71 +2 N 71 +1 E 72 +2 O 72 +1 E 73 +2 P 73 +1 E 74 +2 Q 74 +1 E 75 +2 R 75 +1 F 76 +2 G 76 +1 F 77 +2 H 77 +1 F 78 +2 I 78 +1 F 79 +2 J 79 +1 F 80 +2 K 80 +1 F 81 +2 L 81 +1 F 82 +2 M 82 +1 F 83 +2 N 83 +1 F 84 +2 O 84 +1 F 85 +2 P 85 +1 F 86 +2 Q 86 +1 F 87 +2 R 87 +1 G 88 +2 H 88 +1 G 89 +2 I 89 +1 G 90 +2 J 90 +1 G 91 +2 K 91 +1 G 92 +2 L 92 +1 G 93 +2 M 93 +1 G 94 +2 N 94 +1 G 95 +2 O 95 +1 G 96 +2 P 96 +1 G 97 +2 Q 97 +1 G 98 +2 R 98 +1 H 99 +2 I 99 +1 H 100 +2 J 100 +1 H 101 +2 K 101 +1 H 102 +2 L 102 +1 H 103 +2 M 103 +1 H 104 +2 N 104 +1 H 105 +2 O 105 +1 H 106 +2 P 106 +1 H 107 +2 Q 107 +1 H 108 +2 R 108 +1 I 109 +2 J 109 +1 I 110 +2 K 110 +1 I 111 +2 L 111 +1 I 112 +2 M 112 +1 I 113 +2 N 113 +1 I 114 +2 O 114 +1 I 115 +2 P 115 +1 I 116 +2 Q 116 +1 I 117 +2 R 117 +1 J 118 +2 K 118 +1 J 119 +2 L 119 +1 J 120 +2 M 120 +1 J 121 +2 N 121 +1 J 122 +2 O 122 +1 J 123 +2 P 123 +1 J 124 +2 Q 124 +1 J 125 +2 R 125 +1 K 126 +2 L 126 +1 K 127 +2 M 127 +1 K 128 +2 N 128 +1 K 129 +2 O 129 +1 K 130 +2 P 130 +1 K 131 +2 Q 131 +1 K 132 +2 R 132 +1 L 133 +2 M 133 +1 L 134 +2 N 134 +1 L 135 +2 O 135 +1 L 136 +2 P 136 +1 L 137 +2 Q 137 +1 L 138 +2 R 138 +1 M 139 +2 N 139 +1 M 140 +2 O 140 +1 M 141 +2 P 141 +1 M 142 +2 Q 142 +1 M 143 +2 R 143 +1 N 144 +2 O 144 +1 N 145 +2 P 145 +1 N 146 +2 Q 146 +1 N 147 +2 R 147 +1 O 148 +2 P 148 +1 O 149 +2 Q 149 +1 O 150 +2 R 150 +1 P 151 +2 Q 151 +1 P 152 +2 R 152 +1 Q 153 +2 R 153 +# +loop_ +_struct_ncs_dom_lim.dom_id +_struct_ncs_dom_lim.beg_auth_asym_id +_struct_ncs_dom_lim.beg_auth_seq_id +_struct_ncs_dom_lim.end_auth_asym_id +_struct_ncs_dom_lim.end_auth_seq_id +_struct_ncs_dom_lim.pdbx_component_id +_struct_ncs_dom_lim.pdbx_refine_code +_struct_ncs_dom_lim.beg_label_asym_id +_struct_ncs_dom_lim.beg_label_comp_id +_struct_ncs_dom_lim.beg_label_seq_id +_struct_ncs_dom_lim.beg_label_alt_id +_struct_ncs_dom_lim.end_label_asym_id +_struct_ncs_dom_lim.end_label_comp_id +_struct_ncs_dom_lim.end_label_seq_id +_struct_ncs_dom_lim.end_label_alt_id +_struct_ncs_dom_lim.pdbx_ens_id +_struct_ncs_dom_lim.selection_details +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 1 ? +2 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 1 ? +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 2 ? +2 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 2 ? +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 3 ? +2 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 3 ? +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 4 ? +2 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 4 ? +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 5 ? +2 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 5 ? +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 6 ? +2 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 6 ? +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 7 ? +2 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 7 ? +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 8 ? +2 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 8 ? +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 9 ? +2 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 9 ? +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 10 ? +2 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 10 ? +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 11 ? +2 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 11 ? +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 12 ? +2 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 12 ? +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 13 ? +2 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 13 ? +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 14 ? +2 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 14 ? +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 15 ? +2 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 15 ? +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 16 ? +2 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 16 ? +1 A 2 A 257 0 0 ? ? ? ? ? ? ? ? 17 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 17 ? +1 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 18 ? +2 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 18 ? +1 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 19 ? +2 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 19 ? +1 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 20 ? +2 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 20 ? +1 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 21 ? +2 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 21 ? +1 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 22 ? +2 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 22 ? +1 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 23 ? +2 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 23 ? +1 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 24 ? +2 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 24 ? +1 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 25 ? +2 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 25 ? +1 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 26 ? +2 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 26 ? +1 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 27 ? +2 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 27 ? +1 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 28 ? +2 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 28 ? +1 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 29 ? +2 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 29 ? +1 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 30 ? +2 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 30 ? +1 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 31 ? +2 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 31 ? +1 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 32 ? +2 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 32 ? +1 B 2 B 257 0 0 ? ? ? ? ? ? ? ? 33 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 33 ? +1 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 34 ? +2 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 34 ? +1 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 35 ? +2 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 35 ? +1 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 36 ? +2 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 36 ? +1 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 37 ? +2 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 37 ? +1 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 38 ? +2 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 38 ? +1 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 39 ? +2 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 39 ? +1 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 40 ? +2 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 40 ? +1 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 41 ? +2 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 41 ? +1 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 42 ? +2 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 42 ? +1 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 43 ? +2 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 43 ? +1 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 44 ? +2 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 44 ? +1 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 45 ? +2 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 45 ? +1 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 46 ? +2 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 46 ? +1 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 47 ? +2 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 47 ? +1 C 2 C 257 0 0 ? ? ? ? ? ? ? ? 48 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 48 ? +1 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 49 ? +2 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 49 ? +1 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 50 ? +2 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 50 ? +1 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 51 ? +2 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 51 ? +1 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 52 ? +2 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 52 ? +1 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 53 ? +2 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 53 ? +1 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 54 ? +2 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 54 ? +1 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 55 ? +2 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 55 ? +1 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 56 ? +2 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 56 ? +1 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 57 ? +2 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 57 ? +1 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 58 ? +2 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 58 ? +1 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 59 ? +2 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 59 ? +1 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 60 ? +2 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 60 ? +1 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 61 ? +2 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 61 ? +1 D 2 D 257 0 0 ? ? ? ? ? ? ? ? 62 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 62 ? +1 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 63 ? +2 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 63 ? +1 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 64 ? +2 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 64 ? +1 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 65 ? +2 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 65 ? +1 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 66 ? +2 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 66 ? +1 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 67 ? +2 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 67 ? +1 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 68 ? +2 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 68 ? +1 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 69 ? +2 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 69 ? +1 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 70 ? +2 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 70 ? +1 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 71 ? +2 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 71 ? +1 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 72 ? +2 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 72 ? +1 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 73 ? +2 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 73 ? +1 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 74 ? +2 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 74 ? +1 E 2 E 257 0 0 ? ? ? ? ? ? ? ? 75 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 75 ? +1 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 76 ? +2 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 76 ? +1 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 77 ? +2 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 77 ? +1 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 78 ? +2 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 78 ? +1 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 79 ? +2 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 79 ? +1 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 80 ? +2 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 80 ? +1 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 81 ? +2 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 81 ? +1 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 82 ? +2 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 82 ? +1 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 83 ? +2 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 83 ? +1 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 84 ? +2 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 84 ? +1 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 85 ? +2 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 85 ? +1 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 86 ? +2 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 86 ? +1 F 2 F 257 0 0 ? ? ? ? ? ? ? ? 87 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 87 ? +1 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 88 ? +2 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 88 ? +1 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 89 ? +2 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 89 ? +1 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 90 ? +2 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 90 ? +1 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 91 ? +2 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 91 ? +1 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 92 ? +2 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 92 ? +1 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 93 ? +2 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 93 ? +1 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 94 ? +2 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 94 ? +1 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 95 ? +2 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 95 ? +1 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 96 ? +2 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 96 ? +1 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 97 ? +2 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 97 ? +1 G 2 G 257 0 0 ? ? ? ? ? ? ? ? 98 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 98 ? +1 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 99 ? +2 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 99 ? +1 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 100 ? +2 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 100 ? +1 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 101 ? +2 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 101 ? +1 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 102 ? +2 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 102 ? +1 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 103 ? +2 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 103 ? +1 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 104 ? +2 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 104 ? +1 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 105 ? +2 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 105 ? +1 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 106 ? +2 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 106 ? +1 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 107 ? +2 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 107 ? +1 H 2 H 257 0 0 ? ? ? ? ? ? ? ? 108 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 108 ? +1 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 109 ? +2 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 109 ? +1 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 110 ? +2 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 110 ? +1 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 111 ? +2 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 111 ? +1 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 112 ? +2 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 112 ? +1 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 113 ? +2 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 113 ? +1 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 114 ? +2 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 114 ? +1 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 115 ? +2 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 115 ? +1 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 116 ? +2 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 116 ? +1 I 2 I 257 0 0 ? ? ? ? ? ? ? ? 117 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 117 ? +1 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 118 ? +2 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 118 ? +1 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 119 ? +2 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 119 ? +1 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 120 ? +2 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 120 ? +1 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 121 ? +2 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 121 ? +1 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 122 ? +2 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 122 ? +1 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 123 ? +2 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 123 ? +1 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 124 ? +2 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 124 ? +1 J 2 J 257 0 0 ? ? ? ? ? ? ? ? 125 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 125 ? +1 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 126 ? +2 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 126 ? +1 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 127 ? +2 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 127 ? +1 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 128 ? +2 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 128 ? +1 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 129 ? +2 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 129 ? +1 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 130 ? +2 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 130 ? +1 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 131 ? +2 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 131 ? +1 K 2 K 257 0 0 ? ? ? ? ? ? ? ? 132 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 132 ? +1 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 133 ? +2 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 133 ? +1 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 134 ? +2 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 134 ? +1 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 135 ? +2 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 135 ? +1 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 136 ? +2 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 136 ? +1 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 137 ? +2 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 137 ? +1 L 2 L 257 0 0 ? ? ? ? ? ? ? ? 138 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 138 ? +1 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 139 ? +2 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 139 ? +1 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 140 ? +2 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 140 ? +1 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 141 ? +2 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 141 ? +1 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 142 ? +2 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 142 ? +1 M 2 M 257 0 0 ? ? ? ? ? ? ? ? 143 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 143 ? +1 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 144 ? +2 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 144 ? +1 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 145 ? +2 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 145 ? +1 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 146 ? +2 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 146 ? +1 N 2 N 257 0 0 ? ? ? ? ? ? ? ? 147 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 147 ? +1 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 148 ? +2 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 148 ? +1 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 149 ? +2 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 149 ? +1 O 2 O 257 0 0 ? ? ? ? ? ? ? ? 150 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 150 ? +1 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 151 ? +2 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 151 ? +1 P 2 P 257 0 0 ? ? ? ? ? ? ? ? 152 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 152 ? +1 Q 2 Q 257 0 0 ? ? ? ? ? ? ? ? 153 ? +2 R 2 R 257 0 0 ? ? ? ? ? ? ? ? 153 ? +# +loop_ +_struct_ncs_ens.id +_struct_ncs_ens.details +1 ? +2 ? +3 ? +4 ? +5 ? +6 ? +7 ? +8 ? +9 ? +10 ? +11 ? +12 ? +13 ? +14 ? +15 ? +16 ? +17 ? +18 ? +19 ? +20 ? +21 ? +22 ? +23 ? +24 ? +25 ? +26 ? +27 ? +28 ? +29 ? +30 ? +31 ? +32 ? +33 ? +34 ? +35 ? +36 ? +37 ? +38 ? +39 ? +40 ? +41 ? +42 ? +43 ? +44 ? +45 ? +46 ? +47 ? +48 ? +49 ? +50 ? +51 ? +52 ? +53 ? +54 ? +55 ? +56 ? +57 ? +58 ? +59 ? +60 ? +61 ? +62 ? +63 ? +64 ? +65 ? +66 ? +67 ? +68 ? +69 ? +70 ? +71 ? +72 ? +73 ? +74 ? +75 ? +76 ? +77 ? +78 ? +79 ? +80 ? +81 ? +82 ? +83 ? +84 ? +85 ? +86 ? +87 ? +88 ? +89 ? +90 ? +91 ? +92 ? +93 ? +94 ? +95 ? +96 ? +97 ? +98 ? +99 ? +100 ? +101 ? +102 ? +103 ? +104 ? +105 ? +106 ? +107 ? +108 ? +109 ? +110 ? +111 ? +112 ? +113 ? +114 ? +115 ? +116 ? +117 ? +118 ? +119 ? +120 ? +121 ? +122 ? +123 ? +124 ? +125 ? +126 ? +127 ? +128 ? +129 ? +130 ? +131 ? +132 ? +133 ? +134 ? +135 ? +136 ? +137 ? +138 ? +139 ? +140 ? +141 ? +142 ? +143 ? +144 ? +145 ? +146 ? +147 ? +148 ? +149 ? +150 ? +151 ? +152 ? +153 ? +# +_struct.entry_id 4UV3 +_struct.title 'Structure of the curli transport lipoprotein CsgG in its membrane- bound conformation' +_struct.pdbx_descriptor 'CURLI PRODUCTION ASSEMBLY/TRANSPORT COMPONENT CSGG' +_struct.pdbx_model_details ? +_struct.pdbx_CASP_flag ? +_struct.pdbx_model_type_details ? +# +_struct_keywords.entry_id 4UV3 +_struct_keywords.pdbx_keywords 'TRANSPORT PROTEIN' +_struct_keywords.text 'TRANSPORT PROTEIN, CSGG, CURLI TRANSPORTER, OUTER MEMBRANE LIPOPROTEIN, AMYLOID' +# +loop_ +_struct_asym.id +_struct_asym.pdbx_blank_PDB_chainid_flag +_struct_asym.pdbx_modified +_struct_asym.entity_id +_struct_asym.details +A N N 1 ? +B N N 1 ? +C N N 1 ? +D N N 1 ? +E N N 1 ? +F N N 1 ? +G N N 1 ? +H N N 1 ? +I N N 1 ? +J N N 1 ? +K N N 1 ? +L N N 1 ? +M N N 1 ? +N N N 1 ? +O N N 1 ? +P N N 1 ? +Q N N 1 ? +R N N 1 ? +# +_struct_biol.id 1 +# +loop_ +_struct_conf.conf_type_id +_struct_conf.id +_struct_conf.pdbx_PDB_helix_id +_struct_conf.beg_label_comp_id +_struct_conf.beg_label_asym_id +_struct_conf.beg_label_seq_id +_struct_conf.pdbx_beg_PDB_ins_code +_struct_conf.end_label_comp_id +_struct_conf.end_label_asym_id +_struct_conf.end_label_seq_id +_struct_conf.pdbx_end_PDB_ins_code +_struct_conf.beg_auth_comp_id +_struct_conf.beg_auth_asym_id +_struct_conf.beg_auth_seq_id +_struct_conf.end_auth_comp_id +_struct_conf.end_auth_asym_id +_struct_conf.end_auth_seq_id +_struct_conf.pdbx_PDB_helix_class +_struct_conf.details +_struct_conf.pdbx_PDB_helix_length +HELX_P HELX_P1 1 ALA A 18 ? HIS A 26 ? ALA A 18 HIS A 26 1 ? 9 +HELX_P HELX_P2 2 SER A 63 ? SER A 75 ? SER A 63 SER A 75 1 ? 13 +HELX_P HELX_P3 3 GLY A 85 ? GLU A 101 ? GLY A 85 GLU A 101 1 ? 17 +HELX_P HELX_P4 4 PRO A 211 ? ARG A 234 ? PRO A 211 ARG A 234 1 ? 24 +HELX_P HELX_P5 5 ASN A 241 ? GLN A 246 ? ASN A 241 GLN A 246 5 ? 6 +HELX_P HELX_P6 6 ASN A 247 ? SER A 257 ? ASN A 247 SER A 257 1 ? 11 +HELX_P HELX_P7 7 ALA B 18 ? HIS B 26 ? ALA B 18 HIS B 26 1 ? 9 +HELX_P HELX_P8 8 SER B 63 ? SER B 75 ? SER B 63 SER B 75 1 ? 13 +HELX_P HELX_P9 9 GLY B 85 ? GLU B 101 ? GLY B 85 GLU B 101 1 ? 17 +HELX_P HELX_P10 10 PRO B 211 ? ARG B 234 ? PRO B 211 ARG B 234 1 ? 24 +HELX_P HELX_P11 11 ASN B 241 ? GLN B 246 ? ASN B 241 GLN B 246 5 ? 6 +HELX_P HELX_P12 12 ASN B 247 ? SER B 257 ? ASN B 247 SER B 257 1 ? 11 +HELX_P HELX_P13 13 ALA C 18 ? HIS C 26 ? ALA C 18 HIS C 26 1 ? 9 +HELX_P HELX_P14 14 SER C 63 ? SER C 75 ? SER C 63 SER C 75 1 ? 13 +HELX_P HELX_P15 15 GLY C 85 ? GLU C 101 ? GLY C 85 GLU C 101 1 ? 17 +HELX_P HELX_P16 16 PRO C 211 ? ARG C 234 ? PRO C 211 ARG C 234 1 ? 24 +HELX_P HELX_P17 17 ASN C 241 ? GLN C 246 ? ASN C 241 GLN C 246 5 ? 6 +HELX_P HELX_P18 18 ASN C 247 ? SER C 257 ? ASN C 247 SER C 257 1 ? 11 +HELX_P HELX_P19 19 ALA D 18 ? HIS D 26 ? ALA D 18 HIS D 26 1 ? 9 +HELX_P HELX_P20 20 SER D 63 ? SER D 75 ? SER D 63 SER D 75 1 ? 13 +HELX_P HELX_P21 21 GLY D 85 ? GLU D 101 ? GLY D 85 GLU D 101 1 ? 17 +HELX_P HELX_P22 22 PRO D 211 ? ARG D 234 ? PRO D 211 ARG D 234 1 ? 24 +HELX_P HELX_P23 23 ASN D 241 ? GLN D 246 ? ASN D 241 GLN D 246 5 ? 6 +HELX_P HELX_P24 24 ASN D 247 ? SER D 257 ? ASN D 247 SER D 257 1 ? 11 +HELX_P HELX_P25 25 ALA E 18 ? HIS E 26 ? ALA E 18 HIS E 26 1 ? 9 +HELX_P HELX_P26 26 SER E 63 ? SER E 75 ? SER E 63 SER E 75 1 ? 13 +HELX_P HELX_P27 27 GLY E 85 ? GLU E 101 ? GLY E 85 GLU E 101 1 ? 17 +HELX_P HELX_P28 28 PRO E 211 ? ARG E 234 ? PRO E 211 ARG E 234 1 ? 24 +HELX_P HELX_P29 29 ASN E 241 ? GLN E 246 ? ASN E 241 GLN E 246 5 ? 6 +HELX_P HELX_P30 30 ASN E 247 ? SER E 257 ? ASN E 247 SER E 257 1 ? 11 +HELX_P HELX_P31 31 ALA F 18 ? HIS F 26 ? ALA F 18 HIS F 26 1 ? 9 +HELX_P HELX_P32 32 SER F 63 ? SER F 75 ? SER F 63 SER F 75 1 ? 13 +HELX_P HELX_P33 33 GLY F 85 ? GLU F 101 ? GLY F 85 GLU F 101 1 ? 17 +HELX_P HELX_P34 34 PRO F 211 ? ARG F 234 ? PRO F 211 ARG F 234 1 ? 24 +HELX_P HELX_P35 35 ASN F 241 ? GLN F 246 ? ASN F 241 GLN F 246 5 ? 6 +HELX_P HELX_P36 36 ASN F 247 ? SER F 257 ? ASN F 247 SER F 257 1 ? 11 +HELX_P HELX_P37 37 ALA G 18 ? HIS G 26 ? ALA G 18 HIS G 26 1 ? 9 +HELX_P HELX_P38 38 SER G 63 ? SER G 75 ? SER G 63 SER G 75 1 ? 13 +HELX_P HELX_P39 39 GLY G 85 ? GLU G 101 ? GLY G 85 GLU G 101 1 ? 17 +HELX_P HELX_P40 40 PRO G 211 ? GLY G 235 ? PRO G 211 GLY G 235 1 ? 25 +HELX_P HELX_P41 41 ASN G 241 ? GLN G 246 ? ASN G 241 GLN G 246 5 ? 6 +HELX_P HELX_P42 42 ASN G 247 ? SER G 257 ? ASN G 247 SER G 257 1 ? 11 +HELX_P HELX_P43 43 ALA H 18 ? HIS H 26 ? ALA H 18 HIS H 26 1 ? 9 +HELX_P HELX_P44 44 SER H 63 ? SER H 75 ? SER H 63 SER H 75 1 ? 13 +HELX_P HELX_P45 45 GLY H 85 ? GLU H 101 ? GLY H 85 GLU H 101 1 ? 17 +HELX_P HELX_P46 46 PRO H 211 ? ARG H 234 ? PRO H 211 ARG H 234 1 ? 24 +HELX_P HELX_P47 47 ASN H 241 ? GLN H 246 ? ASN H 241 GLN H 246 5 ? 6 +HELX_P HELX_P48 48 ASN H 247 ? SER H 257 ? ASN H 247 SER H 257 1 ? 11 +HELX_P HELX_P49 49 ALA I 18 ? HIS I 26 ? ALA I 18 HIS I 26 1 ? 9 +HELX_P HELX_P50 50 SER I 63 ? SER I 75 ? SER I 63 SER I 75 1 ? 13 +HELX_P HELX_P51 51 GLY I 85 ? GLU I 101 ? GLY I 85 GLU I 101 1 ? 17 +HELX_P HELX_P52 52 PRO I 211 ? ARG I 234 ? PRO I 211 ARG I 234 1 ? 24 +HELX_P HELX_P53 53 ASN I 241 ? GLN I 246 ? ASN I 241 GLN I 246 5 ? 6 +HELX_P HELX_P54 54 ASN I 247 ? SER I 257 ? ASN I 247 SER I 257 1 ? 11 +HELX_P HELX_P55 55 ALA J 18 ? HIS J 26 ? ALA J 18 HIS J 26 1 ? 9 +HELX_P HELX_P56 56 SER J 63 ? SER J 75 ? SER J 63 SER J 75 1 ? 13 +HELX_P HELX_P57 57 GLY J 85 ? GLU J 101 ? GLY J 85 GLU J 101 1 ? 17 +HELX_P HELX_P58 58 PRO J 211 ? ARG J 234 ? PRO J 211 ARG J 234 1 ? 24 +HELX_P HELX_P59 59 ASN J 241 ? GLN J 246 ? ASN J 241 GLN J 246 5 ? 6 +HELX_P HELX_P60 60 ASN J 247 ? SER J 257 ? ASN J 247 SER J 257 1 ? 11 +HELX_P HELX_P61 61 ALA K 18 ? HIS K 26 ? ALA K 18 HIS K 26 1 ? 9 +HELX_P HELX_P62 62 SER K 63 ? SER K 75 ? SER K 63 SER K 75 1 ? 13 +HELX_P HELX_P63 63 GLY K 85 ? GLU K 101 ? GLY K 85 GLU K 101 1 ? 17 +HELX_P HELX_P64 64 PRO K 211 ? ARG K 234 ? PRO K 211 ARG K 234 1 ? 24 +HELX_P HELX_P65 65 ASN K 241 ? GLN K 246 ? ASN K 241 GLN K 246 5 ? 6 +HELX_P HELX_P66 66 ASN K 247 ? SER K 257 ? ASN K 247 SER K 257 1 ? 11 +HELX_P HELX_P67 67 ALA L 18 ? HIS L 26 ? ALA L 18 HIS L 26 1 ? 9 +HELX_P HELX_P68 68 SER L 63 ? SER L 75 ? SER L 63 SER L 75 1 ? 13 +HELX_P HELX_P69 69 GLY L 85 ? GLU L 101 ? GLY L 85 GLU L 101 1 ? 17 +HELX_P HELX_P70 70 PRO L 211 ? ARG L 234 ? PRO L 211 ARG L 234 1 ? 24 +HELX_P HELX_P71 71 ASN L 241 ? GLN L 246 ? ASN L 241 GLN L 246 5 ? 6 +HELX_P HELX_P72 72 ASN L 247 ? SER L 257 ? ASN L 247 SER L 257 1 ? 11 +HELX_P HELX_P73 73 ALA M 18 ? HIS M 26 ? ALA M 18 HIS M 26 1 ? 9 +HELX_P HELX_P74 74 SER M 63 ? SER M 75 ? SER M 63 SER M 75 1 ? 13 +HELX_P HELX_P75 75 GLY M 85 ? GLU M 101 ? GLY M 85 GLU M 101 1 ? 17 +HELX_P HELX_P76 76 PRO M 211 ? ARG M 234 ? PRO M 211 ARG M 234 1 ? 24 +HELX_P HELX_P77 77 ASN M 241 ? GLN M 246 ? ASN M 241 GLN M 246 5 ? 6 +HELX_P HELX_P78 78 ASN M 247 ? SER M 257 ? ASN M 247 SER M 257 1 ? 11 +HELX_P HELX_P79 79 ALA N 18 ? HIS N 26 ? ALA N 18 HIS N 26 1 ? 9 +HELX_P HELX_P80 80 SER N 63 ? SER N 75 ? SER N 63 SER N 75 1 ? 13 +HELX_P HELX_P81 81 GLY N 85 ? GLU N 101 ? GLY N 85 GLU N 101 1 ? 17 +HELX_P HELX_P82 82 PRO N 211 ? ARG N 234 ? PRO N 211 ARG N 234 1 ? 24 +HELX_P HELX_P83 83 ASN N 241 ? GLN N 246 ? ASN N 241 GLN N 246 5 ? 6 +HELX_P HELX_P84 84 ASN N 247 ? SER N 257 ? ASN N 247 SER N 257 1 ? 11 +HELX_P HELX_P85 85 ALA O 18 ? HIS O 26 ? ALA O 18 HIS O 26 1 ? 9 +HELX_P HELX_P86 86 SER O 63 ? SER O 75 ? SER O 63 SER O 75 1 ? 13 +HELX_P HELX_P87 87 GLY O 85 ? GLU O 101 ? GLY O 85 GLU O 101 1 ? 17 +HELX_P HELX_P88 88 PRO O 211 ? ARG O 234 ? PRO O 211 ARG O 234 1 ? 24 +HELX_P HELX_P89 89 ASN O 241 ? GLN O 246 ? ASN O 241 GLN O 246 5 ? 6 +HELX_P HELX_P90 90 ASN O 247 ? SER O 257 ? ASN O 247 SER O 257 1 ? 11 +HELX_P HELX_P91 91 ALA P 18 ? HIS P 26 ? ALA P 18 HIS P 26 1 ? 9 +HELX_P HELX_P92 92 SER P 63 ? SER P 75 ? SER P 63 SER P 75 1 ? 13 +HELX_P HELX_P93 93 GLY P 85 ? GLU P 101 ? GLY P 85 GLU P 101 1 ? 17 +HELX_P HELX_P94 94 PRO P 211 ? ARG P 234 ? PRO P 211 ARG P 234 1 ? 24 +HELX_P HELX_P95 95 ASN P 241 ? GLN P 246 ? ASN P 241 GLN P 246 5 ? 6 +HELX_P HELX_P96 96 ASN P 247 ? SER P 257 ? ASN P 247 SER P 257 1 ? 11 +HELX_P HELX_P97 97 ALA Q 18 ? HIS Q 26 ? ALA Q 18 HIS Q 26 1 ? 9 +HELX_P HELX_P98 98 SER Q 63 ? SER Q 75 ? SER Q 63 SER Q 75 1 ? 13 +HELX_P HELX_P99 99 GLY Q 85 ? GLU Q 101 ? GLY Q 85 GLU Q 101 1 ? 17 +HELX_P HELX_P100 100 PRO Q 211 ? ARG Q 234 ? PRO Q 211 ARG Q 234 1 ? 24 +HELX_P HELX_P101 101 ASN Q 241 ? GLN Q 246 ? ASN Q 241 GLN Q 246 5 ? 6 +HELX_P HELX_P102 102 ASN Q 247 ? SER Q 257 ? ASN Q 247 SER Q 257 1 ? 11 +HELX_P HELX_P103 103 ALA R 18 ? HIS R 26 ? ALA R 18 HIS R 26 1 ? 9 +HELX_P HELX_P104 104 SER R 63 ? SER R 75 ? SER R 63 SER R 75 1 ? 13 +HELX_P HELX_P105 105 GLY R 85 ? GLU R 101 ? GLY R 85 GLU R 101 1 ? 17 +HELX_P HELX_P106 106 PRO R 211 ? GLY R 235 ? PRO R 211 GLY R 235 1 ? 25 +HELX_P HELX_P107 107 ASN R 241 ? GLN R 246 ? ASN R 241 GLN R 246 5 ? 6 +HELX_P HELX_P108 108 ASN R 247 ? SER R 257 ? ASN R 247 SER R 257 1 ? 11 +# +_struct_conf_type.id HELX_P +_struct_conf_type.criteria ? +_struct_conf_type.reference ? +# +loop_ +_struct_mon_prot_cis.pdbx_id +_struct_mon_prot_cis.label_comp_id +_struct_mon_prot_cis.label_seq_id +_struct_mon_prot_cis.label_asym_id +_struct_mon_prot_cis.label_alt_id +_struct_mon_prot_cis.pdbx_PDB_ins_code +_struct_mon_prot_cis.auth_comp_id +_struct_mon_prot_cis.auth_seq_id +_struct_mon_prot_cis.auth_asym_id +_struct_mon_prot_cis.pdbx_label_comp_id_2 +_struct_mon_prot_cis.pdbx_label_seq_id_2 +_struct_mon_prot_cis.pdbx_label_asym_id_2 +_struct_mon_prot_cis.pdbx_PDB_ins_code_2 +_struct_mon_prot_cis.pdbx_auth_comp_id_2 +_struct_mon_prot_cis.pdbx_auth_seq_id_2 +_struct_mon_prot_cis.pdbx_auth_asym_id_2 +_struct_mon_prot_cis.pdbx_PDB_model_num +_struct_mon_prot_cis.pdbx_omega_angle +1 TYR 51 A . ? TYR 51 A PRO 52 A ? PRO 52 A 1 7.91 +2 TYR 51 B . ? TYR 51 B PRO 52 B ? PRO 52 B 1 8.44 +3 TYR 51 C . ? TYR 51 C PRO 52 C ? PRO 52 C 1 6.71 +4 TYR 51 D . ? TYR 51 D PRO 52 D ? PRO 52 D 1 9.36 +5 TYR 51 E . ? TYR 51 E PRO 52 E ? PRO 52 E 1 7.85 +6 TYR 51 F . ? TYR 51 F PRO 52 F ? PRO 52 F 1 6.58 +7 TYR 51 G . ? TYR 51 G PRO 52 G ? PRO 52 G 1 7.79 +8 TYR 51 H . ? TYR 51 H PRO 52 H ? PRO 52 H 1 12.62 +9 TYR 51 I . ? TYR 51 I PRO 52 I ? PRO 52 I 1 8.95 +10 TYR 51 J . ? TYR 51 J PRO 52 J ? PRO 52 J 1 12.45 +11 TYR 51 K . ? TYR 51 K PRO 52 K ? PRO 52 K 1 8.03 +12 TYR 51 L . ? TYR 51 L PRO 52 L ? PRO 52 L 1 8.29 +13 TYR 51 M . ? TYR 51 M PRO 52 M ? PRO 52 M 1 8.45 +14 TYR 51 N . ? TYR 51 N PRO 52 N ? PRO 52 N 1 8.04 +15 TYR 51 O . ? TYR 51 O PRO 52 O ? PRO 52 O 1 8.77 +16 TYR 51 P . ? TYR 51 P PRO 52 P ? PRO 52 P 1 8.47 +17 TYR 51 Q . ? TYR 51 Q PRO 52 Q ? PRO 52 Q 1 6.60 +18 TYR 51 R . ? TYR 51 R PRO 52 R ? PRO 52 R 1 7.97 +# +loop_ +_struct_sheet.id +_struct_sheet.type +_struct_sheet.number_strands +_struct_sheet.details +AA ? 4 ? +AB ? 2 ? +JA ? 4 ? +JB ? 2 ? +# +loop_ +_struct_sheet_order.sheet_id +_struct_sheet_order.range_id_1 +_struct_sheet_order.range_id_2 +_struct_sheet_order.offset +_struct_sheet_order.sense +AA 1 2 ? parallel +AA 2 3 ? anti-parallel +AA 3 4 ? anti-parallel +AB 1 2 ? parallel +JA 1 2 ? parallel +JA 2 3 ? anti-parallel +JA 3 4 ? anti-parallel +JB 1 2 ? parallel +# +loop_ +_struct_sheet_range.sheet_id +_struct_sheet_range.id +_struct_sheet_range.beg_label_comp_id +_struct_sheet_range.beg_label_asym_id +_struct_sheet_range.beg_label_seq_id +_struct_sheet_range.pdbx_beg_PDB_ins_code +_struct_sheet_range.end_label_comp_id +_struct_sheet_range.end_label_asym_id +_struct_sheet_range.end_label_seq_id +_struct_sheet_range.pdbx_end_PDB_ins_code +_struct_sheet_range.beg_auth_comp_id +_struct_sheet_range.beg_auth_asym_id +_struct_sheet_range.beg_auth_seq_id +_struct_sheet_range.end_auth_comp_id +_struct_sheet_range.end_auth_asym_id +_struct_sheet_range.end_auth_seq_id +AA 1 THR A 13 ? LEU A 14 ? THR A 13 LEU A 14 +AA 2 ILE I 171 ? VAL I 190 ? ILE I 171 VAL I 190 +AA 3 ILE I 146 ? ASN I 165 ? ILE I 146 ASN I 165 +AA 4 ILE I 121 ? ARG I 142 ? ILE I 121 ARG I 142 +AB 1 THR A 13 ? LEU A 14 ? THR A 13 LEU A 14 +AB 2 ILE I 171 ? VAL I 190 ? ILE I 171 VAL I 190 +JA 1 THR J 13 ? LEU J 14 ? THR J 13 LEU J 14 +JA 2 ILE R 171 ? VAL R 190 ? ILE R 171 VAL R 190 +JA 3 ILE R 146 ? ASN R 165 ? ILE R 146 ASN R 165 +JA 4 ILE R 121 ? ARG R 142 ? ILE R 121 ARG R 142 +JB 1 THR J 13 ? LEU J 14 ? THR J 13 LEU J 14 +JB 2 ILE R 171 ? VAL R 190 ? ILE R 171 VAL R 190 +# +loop_ +_pdbx_struct_sheet_hbond.sheet_id +_pdbx_struct_sheet_hbond.range_id_1 +_pdbx_struct_sheet_hbond.range_id_2 +_pdbx_struct_sheet_hbond.range_1_label_atom_id +_pdbx_struct_sheet_hbond.range_1_label_comp_id +_pdbx_struct_sheet_hbond.range_1_label_asym_id +_pdbx_struct_sheet_hbond.range_1_label_seq_id +_pdbx_struct_sheet_hbond.range_1_PDB_ins_code +_pdbx_struct_sheet_hbond.range_1_auth_atom_id +_pdbx_struct_sheet_hbond.range_1_auth_comp_id +_pdbx_struct_sheet_hbond.range_1_auth_asym_id +_pdbx_struct_sheet_hbond.range_1_auth_seq_id +_pdbx_struct_sheet_hbond.range_2_label_atom_id +_pdbx_struct_sheet_hbond.range_2_label_comp_id +_pdbx_struct_sheet_hbond.range_2_label_asym_id +_pdbx_struct_sheet_hbond.range_2_label_seq_id +_pdbx_struct_sheet_hbond.range_2_PDB_ins_code +_pdbx_struct_sheet_hbond.range_2_auth_atom_id +_pdbx_struct_sheet_hbond.range_2_auth_comp_id +_pdbx_struct_sheet_hbond.range_2_auth_asym_id +_pdbx_struct_sheet_hbond.range_2_auth_seq_id +AA 1 2 N THR A 13 ? N THR A 13 O SER I 178 ? O SER I 178 +AA 2 3 N GLY I 189 ? N GLY I 189 O GLY I 147 ? O GLY I 147 +AA 3 4 N VAL I 164 ? N VAL I 164 O MET I 122 ? O MET I 122 +AB 1 2 N THR A 13 ? N THR A 13 O SER I 178 ? O SER I 178 +JA 1 2 N THR J 13 ? N THR J 13 O SER R 178 ? O SER R 178 +JA 2 3 N GLY R 189 ? N GLY R 189 O GLY R 147 ? O GLY R 147 +JA 3 4 N VAL R 164 ? N VAL R 164 O MET R 122 ? O MET R 122 +JB 1 2 N THR J 13 ? N THR J 13 O SER R 178 ? O SER R 178 +# +_database_PDB_matrix.entry_id 4UV3 +_database_PDB_matrix.origx[1][1] 1.000000 +_database_PDB_matrix.origx[1][2] 0.000000 +_database_PDB_matrix.origx[1][3] 0.000000 +_database_PDB_matrix.origx[2][1] 0.000000 +_database_PDB_matrix.origx[2][2] 1.000000 +_database_PDB_matrix.origx[2][3] 0.000000 +_database_PDB_matrix.origx[3][1] 0.000000 +_database_PDB_matrix.origx[3][2] 0.000000 +_database_PDB_matrix.origx[3][3] 1.000000 +_database_PDB_matrix.origx_vector[1] 0.00000 +_database_PDB_matrix.origx_vector[2] 0.00000 +_database_PDB_matrix.origx_vector[3] 0.00000 +# +_atom_sites.entry_id 4UV3 +_atom_sites.fract_transf_matrix[1][1] 0.006175 +_atom_sites.fract_transf_matrix[1][2] 0.000000 +_atom_sites.fract_transf_matrix[1][3] 0.000313 +_atom_sites.fract_transf_matrix[2][1] 0.000000 +_atom_sites.fract_transf_matrix[2][2] 0.002682 +_atom_sites.fract_transf_matrix[2][3] 0.000000 +_atom_sites.fract_transf_matrix[3][1] 0.000000 +_atom_sites.fract_transf_matrix[3][2] 0.000000 +_atom_sites.fract_transf_matrix[3][3] 0.006182 +_atom_sites.fract_transf_vector[1] 0.00000 +_atom_sites.fract_transf_vector[2] 0.00000 +_atom_sites.fract_transf_vector[3] 0.00000 +# +loop_ +_atom_type.symbol +C +N +O +S +# +loop_ +_atom_site.group_PDB +_atom_site.id +_atom_site.type_symbol +_atom_site.label_atom_id +_atom_site.label_alt_id +_atom_site.label_comp_id +_atom_site.label_asym_id +_atom_site.label_entity_id +_atom_site.label_seq_id +_atom_site.pdbx_PDB_ins_code +_atom_site.Cartn_x +_atom_site.Cartn_y +_atom_site.Cartn_z +_atom_site.occupancy +_atom_site.B_iso_or_equiv +_atom_site.pdbx_formal_charge +_atom_site.auth_seq_id +_atom_site.auth_comp_id +_atom_site.auth_asym_id +_atom_site.auth_atom_id +_atom_site.pdbx_PDB_model_num +ATOM 1 N N . LEU A 1 2 ? 58.798 -55.137 9.066 1.00 133.91 ? 2 LEU A N 1 +ATOM 2 C CA . LEU A 1 2 ? 57.398 -55.272 9.581 1.00 130.54 ? 2 LEU A CA 1 +ATOM 3 C C . LEU A 1 2 ? 57.356 -55.002 11.102 1.00 126.78 ? 2 LEU A C 1 +ATOM 4 O O . LEU A 1 2 ? 57.122 -55.909 11.930 1.00 81.16 ? 2 LEU A O 1 +ATOM 5 C CB . LEU A 1 2 ? 56.813 -56.651 9.235 1.00 129.67 ? 2 LEU A CB 1 +ATOM 6 C CG . LEU A 1 2 ? 56.671 -57.040 7.744 1.00 135.10 ? 2 LEU A CG 1 +ATOM 7 C CD1 . LEU A 1 2 ? 56.096 -58.450 7.648 1.00 137.37 ? 2 LEU A CD1 1 +ATOM 8 C CD2 . LEU A 1 2 ? 55.832 -56.071 6.899 1.00 128.75 ? 2 LEU A CD2 1 +ATOM 9 N N . THR A 1 3 ? 57.711 -53.756 11.428 1.00 137.44 ? 3 THR A N 1 +ATOM 10 C CA . THR A 1 3 ? 57.446 -53.120 12.716 1.00 156.27 ? 3 THR A CA 1 +ATOM 11 C C . THR A 1 3 ? 57.086 -51.618 12.543 1.00 172.69 ? 3 THR A C 1 +ATOM 12 O O . THR A 1 3 ? 56.773 -50.925 13.522 1.00 150.81 ? 3 THR A O 1 +ATOM 13 C CB . THR A 1 3 ? 58.663 -53.186 13.658 1.00 150.05 ? 3 THR A CB 1 +ATOM 14 O OG1 . THR A 1 3 ? 59.717 -52.342 13.149 1.00 197.81 ? 3 THR A OG1 1 +ATOM 15 C CG2 . THR A 1 3 ? 59.143 -54.627 13.840 1.00 116.36 ? 3 THR A CG2 1 +ATOM 16 N N . ALA A 1 4 ? 57.193 -51.104 11.318 1.00 172.36 ? 4 ALA A N 1 +ATOM 17 C CA . ALA A 1 4 ? 56.618 -49.795 10.976 1.00 150.26 ? 4 ALA A CA 1 +ATOM 18 C C . ALA A 1 4 ? 55.082 -49.931 10.827 1.00 132.67 ? 4 ALA A C 1 +ATOM 19 O O . ALA A 1 4 ? 54.524 -50.995 11.103 1.00 125.50 ? 4 ALA A O 1 +ATOM 20 C CB . ALA A 1 4 ? 57.256 -49.246 9.704 1.00 148.57 ? 4 ALA A CB 1 +ATOM 21 N N . PRO A 1 5 ? 54.373 -48.860 10.427 1.00 112.96 ? 5 PRO A N 1 +ATOM 22 C CA . PRO A 1 5 ? 52.942 -49.003 10.718 1.00 112.60 ? 5 PRO A CA 1 +ATOM 23 C C . PRO A 1 5 ? 52.230 -49.757 9.627 1.00 118.25 ? 5 PRO A C 1 +ATOM 24 O O . PRO A 1 5 ? 52.826 -50.027 8.585 1.00 141.63 ? 5 PRO A O 1 +ATOM 25 C CB . PRO A 1 5 ? 52.448 -47.560 10.767 1.00 115.75 ? 5 PRO A CB 1 +ATOM 26 C CG . PRO A 1 5 ? 53.415 -46.772 9.928 1.00 109.65 ? 5 PRO A CG 1 +ATOM 27 C CD . PRO A 1 5 ? 54.698 -47.556 9.818 1.00 98.27 ? 5 PRO A CD 1 +ATOM 28 N N . PRO A 1 6 ? 50.978 -50.146 9.876 1.00 136.67 ? 6 PRO A N 1 +ATOM 29 C CA . PRO A 1 6 ? 50.110 -50.615 8.786 1.00 166.30 ? 6 PRO A CA 1 +ATOM 30 C C . PRO A 1 6 ? 49.462 -49.480 7.973 1.00 160.59 ? 6 PRO A C 1 +ATOM 31 O O . PRO A 1 6 ? 49.262 -48.389 8.485 1.00 122.73 ? 6 PRO A O 1 +ATOM 32 C CB . PRO A 1 6 ? 49.040 -51.432 9.505 1.00 142.58 ? 6 PRO A CB 1 +ATOM 33 C CG . PRO A 1 6 ? 49.086 -51.018 10.929 1.00 130.38 ? 6 PRO A CG 1 +ATOM 34 C CD . PRO A 1 6 ? 50.393 -50.337 11.209 1.00 116.44 ? 6 PRO A CD 1 +ATOM 35 N N . LYS A 1 7 ? 49.190 -49.733 6.695 1.00 149.81 ? 7 LYS A N 1 +ATOM 36 C CA . LYS A 1 7 ? 48.560 -48.729 5.825 1.00 142.84 ? 7 LYS A CA 1 +ATOM 37 C C . LYS A 1 7 ? 47.061 -48.962 5.720 1.00 114.99 ? 7 LYS A C 1 +ATOM 38 O O . LYS A 1 7 ? 46.546 -50.000 6.160 1.00 64.03 ? 7 LYS A O 1 +ATOM 39 C CB . LYS A 1 7 ? 49.184 -48.709 4.417 1.00 156.91 ? 7 LYS A CB 1 +ATOM 40 C CG . LYS A 1 7 ? 50.590 -48.147 4.349 1.00 151.81 ? 7 LYS A CG 1 +ATOM 41 C CD . LYS A 1 7 ? 51.666 -49.215 4.190 1.00 137.38 ? 7 LYS A CD 1 +ATOM 42 C CE . LYS A 1 7 ? 52.997 -48.572 3.828 1.00 122.26 ? 7 LYS A CE 1 +ATOM 43 N NZ . LYS A 1 7 ? 54.153 -49.370 4.323 1.00 130.32 ? 7 LYS A NZ 1 +ATOM 44 N N . GLU A 1 8 ? 46.369 -47.975 5.146 1.00 109.03 ? 8 GLU A N 1 +ATOM 45 C CA . GLU A 1 8 ? 44.911 -47.828 5.306 1.00 105.93 ? 8 GLU A CA 1 +ATOM 46 C C . GLU A 1 8 ? 44.128 -48.923 4.616 1.00 90.77 ? 8 GLU A C 1 +ATOM 47 O O . GLU A 1 8 ? 44.215 -49.100 3.417 1.00 84.71 ? 8 GLU A O 1 +ATOM 48 C CB . GLU A 1 8 ? 44.413 -46.427 4.841 1.00 109.86 ? 8 GLU A CB 1 +ATOM 49 C CG . GLU A 1 8 ? 44.210 -46.209 3.361 1.00 121.39 ? 8 GLU A CG 1 +ATOM 50 C CD . GLU A 1 8 ? 43.553 -44.864 3.059 1.00 129.92 ? 8 GLU A CD 1 +ATOM 51 O OE1 . GLU A 1 8 ? 42.460 -44.580 3.605 1.00 143.56 ? 8 GLU A OE1 1 +ATOM 52 O OE2 . GLU A 1 8 ? 44.081 -44.118 2.209 1.00 121.24 ? 8 GLU A OE2 1 +ATOM 53 N N . ALA A 1 9 ? 43.377 -49.670 5.415 1.00 101.52 ? 9 ALA A N 1 +ATOM 54 C CA . ALA A 1 9 ? 42.424 -50.644 4.920 1.00 103.62 ? 9 ALA A CA 1 +ATOM 55 C C . ALA A 1 9 ? 41.028 -50.013 4.872 1.00 97.03 ? 9 ALA A C 1 +ATOM 56 O O . ALA A 1 9 ? 40.446 -49.720 5.915 1.00 75.01 ? 9 ALA A O 1 +ATOM 57 C CB . ALA A 1 9 ? 42.436 -51.873 5.823 1.00 96.07 ? 9 ALA A CB 1 +ATOM 58 N N . ALA A 1 10 ? 40.515 -49.817 3.650 1.00 89.99 ? 10 ALA A N 1 +ATOM 59 C CA . ALA A 1 10 ? 39.259 -49.091 3.371 1.00 84.62 ? 10 ALA A CA 1 +ATOM 60 C C . ALA A 1 10 ? 39.519 -47.612 3.267 1.00 75.53 ? 10 ALA A C 1 +ATOM 61 O O . ALA A 1 10 ? 40.513 -47.104 3.791 1.00 66.37 ? 10 ALA A O 1 +ATOM 62 C CB . ALA A 1 10 ? 38.168 -49.395 4.401 1.00 87.96 ? 10 ALA A CB 1 +ATOM 63 N N . ARG A 1 11 ? 38.630 -46.921 2.572 1.00 96.51 ? 11 ARG A N 1 +ATOM 64 C CA . ARG A 1 11 ? 38.873 -45.525 2.182 1.00 150.64 ? 11 ARG A CA 1 +ATOM 65 C C . ARG A 1 11 ? 38.074 -44.543 3.052 1.00 139.64 ? 11 ARG A C 1 +ATOM 66 O O . ARG A 1 11 ? 37.003 -44.891 3.526 1.00 158.38 ? 11 ARG A O 1 +ATOM 67 C CB . ARG A 1 11 ? 38.472 -45.323 0.709 1.00 190.90 ? 11 ARG A CB 1 +ATOM 68 C CG . ARG A 1 11 ? 36.979 -45.442 0.439 1.00 205.27 ? 11 ARG A CG 1 +ATOM 69 C CD . ARG A 1 11 ? 36.695 -45.881 -0.994 1.00 195.44 ? 11 ARG A CD 1 +ATOM 70 N NE . ARG A 1 11 ? 36.047 -47.188 -1.042 1.00 190.72 ? 11 ARG A NE 1 +ATOM 71 C CZ . ARG A 1 11 ? 35.609 -47.759 -2.160 1.00 180.65 ? 11 ARG A CZ 1 +ATOM 72 N NH1 . ARG A 1 11 ? 35.777 -47.148 -3.323 1.00 188.61 ? 11 ARG A NH1 1 +ATOM 73 N NH2 . ARG A 1 11 ? 35.007 -48.944 -2.123 1.00 169.43 ? 11 ARG A NH2 1 +ATOM 74 N N . PRO A 1 12 ? 38.558 -43.290 3.210 1.00 108.20 ? 12 PRO A N 1 +ATOM 75 C CA . PRO A 1 12 ? 37.683 -42.267 3.758 1.00 91.67 ? 12 PRO A CA 1 +ATOM 76 C C . PRO A 1 12 ? 36.548 -41.968 2.797 1.00 109.99 ? 12 PRO A C 1 +ATOM 77 O O . PRO A 1 12 ? 36.773 -41.513 1.668 1.00 118.93 ? 12 PRO A O 1 +ATOM 78 C CB . PRO A 1 12 ? 38.590 -41.043 3.899 1.00 89.68 ? 12 PRO A CB 1 +ATOM 79 C CG . PRO A 1 12 ? 39.982 -41.546 3.727 1.00 110.54 ? 12 PRO A CG 1 +ATOM 80 C CD . PRO A 1 12 ? 39.873 -42.742 2.847 1.00 110.32 ? 12 PRO A CD 1 +ATOM 81 N N . THR A 1 13 ? 35.332 -42.296 3.220 1.00 112.33 ? 13 THR A N 1 +ATOM 82 C CA . THR A 1 13 ? 34.130 -41.847 2.529 1.00 105.27 ? 13 THR A CA 1 +ATOM 83 C C . THR A 1 13 ? 33.552 -40.608 3.218 1.00 98.90 ? 13 THR A C 1 +ATOM 84 O O . THR A 1 13 ? 33.871 -40.353 4.377 1.00 92.80 ? 13 THR A O 1 +ATOM 85 C CB . THR A 1 13 ? 33.070 -42.948 2.543 1.00 103.75 ? 13 THR A CB 1 +ATOM 86 O OG1 . THR A 1 13 ? 32.002 -42.576 1.663 1.00 134.18 ? 13 THR A OG1 1 +ATOM 87 C CG2 . THR A 1 13 ? 32.548 -43.233 3.991 1.00 82.49 ? 13 THR A CG2 1 +ATOM 88 N N . LEU A 1 14 ? 32.704 -39.841 2.535 1.00 82.49 ? 14 LEU A N 1 +ATOM 89 C CA . LEU A 1 14 ? 31.968 -38.799 3.259 1.00 78.87 ? 14 LEU A CA 1 +ATOM 90 C C . LEU A 1 14 ? 30.826 -39.483 4.034 1.00 73.13 ? 14 LEU A C 1 +ATOM 91 O O . LEU A 1 14 ? 30.543 -40.643 3.792 1.00 69.10 ? 14 LEU A O 1 +ATOM 92 C CB . LEU A 1 14 ? 31.511 -37.645 2.369 1.00 69.12 ? 14 LEU A CB 1 +ATOM 93 C CG . LEU A 1 14 ? 30.734 -37.983 1.124 1.00 81.33 ? 14 LEU A CG 1 +ATOM 94 C CD1 . LEU A 1 14 ? 29.714 -36.889 0.833 1.00 105.71 ? 14 LEU A CD1 1 +ATOM 95 C CD2 . LEU A 1 14 ? 31.675 -38.111 -0.044 1.00 80.85 ? 14 LEU A CD2 1 +ATOM 96 N N . MET A 1 15 ? 30.308 -38.852 5.079 1.00 74.12 ? 15 MET A N 1 +ATOM 97 C CA . MET A 1 15 ? 29.715 -39.604 6.185 1.00 86.14 ? 15 MET A CA 1 +ATOM 98 C C . MET A 1 15 ? 28.412 -40.284 5.749 1.00 96.79 ? 15 MET A C 1 +ATOM 99 O O . MET A 1 15 ? 27.493 -39.611 5.284 1.00 155.08 ? 15 MET A O 1 +ATOM 100 C CB . MET A 1 15 ? 29.487 -38.705 7.422 1.00 98.24 ? 15 MET A CB 1 +ATOM 101 C CG . MET A 1 15 ? 29.489 -39.487 8.690 1.00 120.85 ? 15 MET A CG 1 +ATOM 102 S SD . MET A 1 15 ? 28.725 -38.568 10.139 1.00 156.66 ? 15 MET A SD 1 +ATOM 103 C CE . MET A 1 15 ? 27.303 -39.496 10.478 1.00 161.32 ? 15 MET A CE 1 +ATOM 104 N N . PRO A 1 16 ? 28.318 -41.622 5.929 1.00 79.96 ? 16 PRO A N 1 +ATOM 105 C CA . PRO A 1 16 ? 27.212 -42.439 5.456 1.00 84.27 ? 16 PRO A CA 1 +ATOM 106 C C . PRO A 1 16 ? 25.853 -42.095 6.105 1.00 94.57 ? 16 PRO A C 1 +ATOM 107 O O . PRO A 1 16 ? 25.363 -42.834 6.962 1.00 109.08 ? 16 PRO A O 1 +ATOM 108 C CB . PRO A 1 16 ? 27.653 -43.867 5.823 1.00 75.99 ? 16 PRO A CB 1 +ATOM 109 C CG . PRO A 1 16 ? 28.570 -43.700 6.964 1.00 62.85 ? 16 PRO A CG 1 +ATOM 110 C CD . PRO A 1 16 ? 29.299 -42.433 6.666 1.00 72.81 ? 16 PRO A CD 1 +ATOM 111 N N . ARG A 1 17 ? 25.197 -41.074 5.566 1.00 83.81 ? 17 ARG A N 1 +ATOM 112 C CA . ARG A 1 17 ? 23.811 -40.777 5.898 1.00 84.48 ? 17 ARG A CA 1 +ATOM 113 C C . ARG A 1 17 ? 22.831 -41.524 4.987 1.00 89.42 ? 17 ARG A C 1 +ATOM 114 O O . ARG A 1 17 ? 23.161 -41.824 3.844 1.00 99.62 ? 17 ARG A O 1 +ATOM 115 C CB . ARG A 1 17 ? 23.579 -39.296 5.752 1.00 86.23 ? 17 ARG A CB 1 +ATOM 116 C CG . ARG A 1 17 ? 23.963 -38.502 6.994 1.00 94.47 ? 17 ARG A CG 1 +ATOM 117 C CD . ARG A 1 17 ? 24.121 -37.009 6.720 1.00 84.78 ? 17 ARG A CD 1 +ATOM 118 N NE . ARG A 1 17 ? 25.406 -36.715 6.094 1.00 114.88 ? 17 ARG A NE 1 +ATOM 119 C CZ . ARG A 1 17 ? 25.739 -35.536 5.583 1.00 122.52 ? 17 ARG A CZ 1 +ATOM 120 N NH1 . ARG A 1 17 ? 24.878 -34.536 5.671 1.00 113.37 ? 17 ARG A NH1 1 +ATOM 121 N NH2 . ARG A 1 17 ? 26.936 -35.350 5.009 1.00 125.33 ? 17 ARG A NH2 1 +ATOM 122 N N . ALA A 1 18 ? 21.687 -41.941 5.530 1.00 90.24 ? 18 ALA A N 1 +ATOM 123 C CA . ALA A 1 18 ? 20.759 -42.807 4.782 1.00 113.56 ? 18 ALA A CA 1 +ATOM 124 C C . ALA A 1 18 ? 19.439 -42.108 4.454 1.00 132.83 ? 18 ALA A C 1 +ATOM 125 O O . ALA A 1 18 ? 19.444 -41.095 3.751 1.00 178.34 ? 18 ALA A O 1 +ATOM 126 C CB . ALA A 1 18 ? 20.509 -44.134 5.502 1.00 119.82 ? 18 ALA A CB 1 +ATOM 127 N N . GLN A 1 19 ? 18.318 -42.648 4.941 1.00 106.56 ? 19 GLN A N 1 +ATOM 128 C CA . GLN A 1 19 ? 17.007 -42.309 4.380 1.00 89.89 ? 19 GLN A CA 1 +ATOM 129 C C . GLN A 1 19 ? 16.592 -40.873 4.703 1.00 85.09 ? 19 GLN A C 1 +ATOM 130 O O . GLN A 1 19 ? 16.177 -40.104 3.825 1.00 69.80 ? 19 GLN A O 1 +ATOM 131 C CB . GLN A 1 19 ? 15.949 -43.281 4.894 1.00 89.81 ? 19 GLN A CB 1 +ATOM 132 C CG . GLN A 1 19 ? 14.573 -43.116 4.254 1.00 108.83 ? 19 GLN A CG 1 +ATOM 133 C CD . GLN A 1 19 ? 14.598 -43.197 2.735 1.00 119.36 ? 19 GLN A CD 1 +ATOM 134 O OE1 . GLN A 1 19 ? 14.918 -44.241 2.161 1.00 111.97 ? 19 GLN A OE1 1 +ATOM 135 N NE2 . GLN A 1 19 ? 14.312 -42.075 2.077 1.00 122.76 ? 19 GLN A NE2 1 +ATOM 136 N N . SER A 1 20 ? 16.698 -40.539 5.986 1.00 104.31 ? 20 SER A N 1 +ATOM 137 C CA . SER A 1 20 ? 16.479 -39.181 6.491 1.00 96.70 ? 20 SER A CA 1 +ATOM 138 C C . SER A 1 20 ? 17.152 -38.119 5.620 1.00 72.43 ? 20 SER A C 1 +ATOM 139 O O . SER A 1 20 ? 16.496 -37.192 5.138 1.00 63.08 ? 20 SER A O 1 +ATOM 140 C CB . SER A 1 20 ? 17.011 -39.085 7.927 1.00 89.10 ? 20 SER A CB 1 +ATOM 141 O OG . SER A 1 20 ? 16.484 -40.145 8.725 1.00 77.08 ? 20 SER A OG 1 +ATOM 142 N N . TYR A 1 21 ? 18.430 -38.333 5.345 1.00 68.45 ? 21 TYR A N 1 +ATOM 143 C CA . TYR A 1 21 ? 19.167 -37.503 4.403 1.00 85.55 ? 21 TYR A CA 1 +ATOM 144 C C . TYR A 1 21 ? 18.499 -37.366 3.017 1.00 95.87 ? 21 TYR A C 1 +ATOM 145 O O . TYR A 1 21 ? 18.366 -36.246 2.481 1.00 61.26 ? 21 TYR A O 1 +ATOM 146 C CB . TYR A 1 21 ? 20.588 -38.046 4.220 1.00 93.17 ? 21 TYR A CB 1 +ATOM 147 C CG . TYR A 1 21 ? 21.450 -37.172 3.329 1.00 108.57 ? 21 TYR A CG 1 +ATOM 148 C CD1 . TYR A 1 21 ? 21.976 -35.977 3.802 1.00 126.46 ? 21 TYR A CD1 1 +ATOM 149 C CD2 . TYR A 1 21 ? 21.727 -37.527 2.014 1.00 112.49 ? 21 TYR A CD2 1 +ATOM 150 C CE1 . TYR A 1 21 ? 22.766 -35.171 3.003 1.00 129.89 ? 21 TYR A CE1 1 +ATOM 151 C CE2 . TYR A 1 21 ? 22.509 -36.716 1.199 1.00 112.91 ? 21 TYR A CE2 1 +ATOM 152 C CZ . TYR A 1 21 ? 23.029 -35.542 1.708 1.00 123.43 ? 21 TYR A CZ 1 +ATOM 153 O OH . TYR A 1 21 ? 23.874 -34.749 0.966 1.00 203.56 ? 21 TYR A OH 1 +ATOM 154 N N . LYS A 1 22 ? 18.157 -38.512 2.407 1.00 107.72 ? 22 LYS A N 1 +ATOM 155 C CA . LYS A 1 22 ? 17.597 -38.548 1.046 1.00 98.71 ? 22 LYS A CA 1 +ATOM 156 C C . LYS A 1 22 ? 16.286 -37.780 0.958 1.00 99.74 ? 22 LYS A C 1 +ATOM 157 O O . LYS A 1 22 ? 16.055 -37.031 0.002 1.00 88.58 ? 22 LYS A O 1 +ATOM 158 C CB . LYS A 1 22 ? 17.368 -39.981 0.603 1.00 91.04 ? 22 LYS A CB 1 +ATOM 159 C CG . LYS A 1 22 ? 18.562 -40.597 -0.083 1.00 123.06 ? 22 LYS A CG 1 +ATOM 160 C CD . LYS A 1 22 ? 18.605 -40.171 -1.561 1.00 165.62 ? 22 LYS A CD 1 +ATOM 161 C CE . LYS A 1 22 ? 18.086 -41.305 -2.457 1.00 198.92 ? 22 LYS A CE 1 +ATOM 162 N NZ . LYS A 1 22 ? 18.977 -42.496 -2.404 1.00 213.03 ? 22 LYS A NZ 1 +ATOM 163 N N . ASP A 1 23 ? 15.476 -37.909 2.006 1.00 93.22 ? 23 ASP A N 1 +ATOM 164 C CA . ASP A 1 23 ? 14.267 -37.109 2.145 1.00 80.35 ? 23 ASP A CA 1 +ATOM 165 C C . ASP A 1 23 ? 14.598 -35.632 2.292 1.00 80.61 ? 23 ASP A C 1 +ATOM 166 O O . ASP A 1 23 ? 13.964 -34.770 1.656 1.00 102.01 ? 23 ASP A O 1 +ATOM 167 C CB . ASP A 1 23 ? 13.455 -37.580 3.353 1.00 66.28 ? 23 ASP A CB 1 +ATOM 168 C CG . ASP A 1 23 ? 12.916 -38.969 3.165 1.00 66.35 ? 23 ASP A CG 1 +ATOM 169 O OD1 . ASP A 1 23 ? 12.425 -39.248 2.048 1.00 65.34 ? 23 ASP A OD1 1 +ATOM 170 O OD2 . ASP A 1 23 ? 12.917 -39.749 4.140 1.00 57.47 ? 23 ASP A OD2 1 +ATOM 171 N N . LEU A 1 24 ? 15.579 -35.344 3.144 1.00 67.72 ? 24 LEU A N 1 +ATOM 172 C CA . LEU A 1 24 ? 15.911 -33.964 3.522 1.00 87.82 ? 24 LEU A CA 1 +ATOM 173 C C . LEU A 1 24 ? 16.468 -33.155 2.349 1.00 89.24 ? 24 LEU A C 1 +ATOM 174 O O . LEU A 1 24 ? 16.185 -31.944 2.219 1.00 66.31 ? 24 LEU A O 1 +ATOM 175 C CB . LEU A 1 24 ? 16.927 -33.975 4.661 1.00 85.84 ? 24 LEU A CB 1 +ATOM 176 C CG . LEU A 1 24 ? 17.407 -32.622 5.210 1.00 83.22 ? 24 LEU A CG 1 +ATOM 177 C CD1 . LEU A 1 24 ? 16.479 -32.097 6.295 1.00 72.58 ? 24 LEU A CD1 1 +ATOM 178 C CD2 . LEU A 1 24 ? 18.820 -32.768 5.752 1.00 104.09 ? 24 LEU A CD2 1 +ATOM 179 N N . THR A 1 25 ? 17.201 -33.844 1.477 1.00 96.34 ? 25 THR A N 1 +ATOM 180 C CA . THR A 1 25 ? 17.815 -33.199 0.317 1.00 110.91 ? 25 THR A CA 1 +ATOM 181 C C . THR A 1 25 ? 16.820 -32.916 -0.795 1.00 110.70 ? 25 THR A C 1 +ATOM 182 O O . THR A 1 25 ? 16.774 -31.789 -1.325 1.00 114.43 ? 25 THR A O 1 +ATOM 183 C CB . THR A 1 25 ? 18.958 -34.053 -0.260 1.00 110.18 ? 25 THR A CB 1 +ATOM 184 O OG1 . THR A 1 25 ? 18.538 -35.413 -0.373 1.00 86.32 ? 25 THR A OG1 1 +ATOM 185 C CG2 . THR A 1 25 ? 20.175 -33.972 0.660 1.00 125.58 ? 25 THR A CG2 1 +ATOM 186 N N . HIS A 1 26 ? 16.006 -33.923 -1.115 1.00 109.50 ? 26 HIS A N 1 +ATOM 187 C CA . HIS A 1 26 ? 15.014 -33.818 -2.180 1.00 115.64 ? 26 HIS A CA 1 +ATOM 188 C C . HIS A 1 26 ? 13.713 -33.153 -1.687 1.00 113.85 ? 26 HIS A C 1 +ATOM 189 O O . HIS A 1 26 ? 12.629 -33.491 -2.131 1.00 128.23 ? 26 HIS A O 1 +ATOM 190 C CB . HIS A 1 26 ? 14.733 -35.204 -2.782 1.00 107.33 ? 26 HIS A CB 1 +ATOM 191 C CG . HIS A 1 26 ? 15.927 -35.820 -3.448 1.00 126.50 ? 26 HIS A CG 1 +ATOM 192 N ND1 . HIS A 1 26 ? 17.023 -36.257 -2.737 1.00 147.22 ? 26 HIS A ND1 1 +ATOM 193 C CD2 . HIS A 1 26 ? 16.229 -36.009 -4.758 1.00 119.04 ? 26 HIS A CD2 1 +ATOM 194 C CE1 . HIS A 1 26 ? 17.935 -36.717 -3.576 1.00 154.32 ? 26 HIS A CE1 1 +ATOM 195 N NE2 . HIS A 1 26 ? 17.484 -36.563 -4.809 1.00 135.51 ? 26 HIS A NE2 1 +ATOM 196 N N . LEU A 1 27 ? 13.831 -32.158 -0.814 1.00 117.51 ? 27 LEU A N 1 +ATOM 197 C CA . LEU A 1 27 ? 12.675 -31.370 -0.389 1.00 104.46 ? 27 LEU A CA 1 +ATOM 198 C C . LEU A 1 27 ? 12.483 -30.202 -1.339 1.00 94.54 ? 27 LEU A C 1 +ATOM 199 O O . LEU A 1 27 ? 13.446 -29.501 -1.666 1.00 106.19 ? 27 LEU A O 1 +ATOM 200 C CB . LEU A 1 27 ? 12.851 -30.851 1.047 1.00 107.62 ? 27 LEU A CB 1 +ATOM 201 C CG . LEU A 1 27 ? 12.382 -31.803 2.149 1.00 106.16 ? 27 LEU A CG 1 +ATOM 202 C CD1 . LEU A 1 27 ? 12.896 -31.360 3.509 1.00 97.91 ? 27 LEU A CD1 1 +ATOM 203 C CD2 . LEU A 1 27 ? 10.869 -31.926 2.164 1.00 102.14 ? 27 LEU A CD2 1 +ATOM 204 N N . PRO A 1 28 ? 11.236 -29.971 -1.766 1.00 82.18 ? 28 PRO A N 1 +ATOM 205 C CA . PRO A 1 28 ? 10.930 -28.847 -2.649 1.00 74.24 ? 28 PRO A CA 1 +ATOM 206 C C . PRO A 1 28 ? 11.317 -27.510 -2.061 1.00 72.59 ? 28 PRO A C 1 +ATOM 207 O O . PRO A 1 28 ? 10.972 -27.209 -0.927 1.00 97.49 ? 28 PRO A O 1 +ATOM 208 C CB . PRO A 1 28 ? 9.421 -28.922 -2.796 1.00 78.48 ? 28 PRO A CB 1 +ATOM 209 C CG . PRO A 1 28 ? 8.942 -29.638 -1.575 1.00 79.74 ? 28 PRO A CG 1 +ATOM 210 C CD . PRO A 1 28 ? 10.019 -30.623 -1.253 1.00 80.54 ? 28 PRO A CD 1 +ATOM 211 N N . ALA A 1 29 ? 12.042 -26.705 -2.817 1.00 79.54 ? 29 ALA A N 1 +ATOM 212 C CA . ALA A 1 29 ? 12.699 -25.516 -2.251 1.00 86.43 ? 29 ALA A CA 1 +ATOM 213 C C . ALA A 1 29 ? 11.698 -24.390 -1.938 1.00 65.83 ? 29 ALA A C 1 +ATOM 214 O O . ALA A 1 29 ? 10.678 -24.247 -2.609 1.00 69.13 ? 29 ALA A O 1 +ATOM 215 C CB . ALA A 1 29 ? 13.821 -25.028 -3.188 1.00 119.04 ? 29 ALA A CB 1 +ATOM 216 N N . PRO A 1 30 ? 11.969 -23.618 -0.891 1.00 61.30 ? 30 PRO A N 1 +ATOM 217 C CA . PRO A 1 30 ? 11.169 -22.435 -0.565 1.00 76.39 ? 30 PRO A CA 1 +ATOM 218 C C . PRO A 1 30 ? 11.400 -21.252 -1.518 1.00 67.69 ? 30 PRO A C 1 +ATOM 219 O O . PRO A 1 30 ? 12.325 -21.290 -2.320 1.00 71.70 ? 30 PRO A O 1 +ATOM 220 C CB . PRO A 1 30 ? 11.675 -22.072 0.839 1.00 94.74 ? 30 PRO A CB 1 +ATOM 221 C CG . PRO A 1 30 ? 13.106 -22.516 0.851 1.00 85.59 ? 30 PRO A CG 1 +ATOM 222 C CD . PRO A 1 30 ? 13.182 -23.718 -0.057 1.00 71.20 ? 30 PRO A CD 1 +ATOM 223 N N . THR A 1 31 ? 10.666 -20.160 -1.314 1.00 71.42 ? 31 THR A N 1 +ATOM 224 C CA . THR A 1 31 ? 10.816 -18.960 -2.151 1.00 93.78 ? 31 THR A CA 1 +ATOM 225 C C . THR A 1 31 ? 12.150 -18.254 -1.937 1.00 95.53 ? 31 THR A C 1 +ATOM 226 O O . THR A 1 31 ? 12.653 -17.560 -2.825 1.00 116.84 ? 31 THR A O 1 +ATOM 227 C CB . THR A 1 31 ? 9.662 -17.935 -1.955 1.00 123.11 ? 31 THR A CB 1 +ATOM 228 O OG1 . THR A 1 31 ? 9.499 -17.603 -0.568 1.00 155.41 ? 31 THR A OG1 1 +ATOM 229 C CG2 . THR A 1 31 ? 8.347 -18.491 -2.495 1.00 132.32 ? 31 THR A CG2 1 +ATOM 230 N N . GLY A 1 32 ? 12.707 -18.405 -0.746 1.00 94.83 ? 32 GLY A N 1 +ATOM 231 C CA . GLY A 1 32 ? 14.061 -17.946 -0.475 1.00 116.34 ? 32 GLY A CA 1 +ATOM 232 C C . GLY A 1 32 ? 14.568 -18.720 0.719 1.00 127.31 ? 32 GLY A C 1 +ATOM 233 O O . GLY A 1 32 ? 13.803 -19.210 1.532 1.00 140.69 ? 32 GLY A O 1 +ATOM 234 N N . LYS A 1 33 ? 15.871 -18.810 0.887 1.00 125.47 ? 33 LYS A N 1 +ATOM 235 C CA . LYS A 1 33 ? 16.376 -19.505 2.051 1.00 117.40 ? 33 LYS A CA 1 +ATOM 236 C C . LYS A 1 33 ? 15.904 -18.746 3.292 1.00 110.90 ? 33 LYS A C 1 +ATOM 237 O O . LYS A 1 33 ? 15.158 -17.710 3.207 1.00 135.50 ? 33 LYS A O 1 +ATOM 238 C CB . LYS A 1 33 ? 17.877 -19.517 1.941 1.00 108.75 ? 33 LYS A CB 1 +ATOM 239 C CG . LYS A 1 33 ? 18.234 -20.159 0.633 1.00 111.72 ? 33 LYS A CG 1 +ATOM 240 C CD . LYS A 1 33 ? 19.606 -19.716 0.203 1.00 143.89 ? 33 LYS A CD 1 +ATOM 241 C CE . LYS A 1 33 ? 19.724 -19.738 -1.309 1.00 167.61 ? 33 LYS A CE 1 +ATOM 242 N NZ . LYS A 1 33 ? 21.010 -19.142 -1.765 1.00 165.51 ? 33 LYS A NZ 1 +ATOM 243 N N . ILE A 1 34 ? 16.157 -19.377 4.426 1.00 92.13 ? 34 ILE A N 1 +ATOM 244 C CA . ILE A 1 34 ? 15.984 -18.693 5.669 1.00 82.25 ? 34 ILE A CA 1 +ATOM 245 C C . ILE A 1 34 ? 17.293 -18.725 6.467 1.00 80.89 ? 34 ILE A C 1 +ATOM 246 O O . ILE A 1 34 ? 18.072 -19.669 6.381 1.00 64.61 ? 34 ILE A O 1 +ATOM 247 C CB . ILE A 1 34 ? 14.767 -19.287 6.408 1.00 104.09 ? 34 ILE A CB 1 +ATOM 248 C CG1 . ILE A 1 34 ? 13.480 -19.048 5.603 1.00 120.54 ? 34 ILE A CG1 1 +ATOM 249 C CG2 . ILE A 1 34 ? 14.580 -18.668 7.778 1.00 124.26 ? 34 ILE A CG2 1 +ATOM 250 C CD1 . ILE A 1 34 ? 12.783 -20.320 5.157 1.00 122.59 ? 34 ILE A CD1 1 +ATOM 251 N N . PHE A 1 35 ? 17.576 -17.607 7.136 1.00 101.91 ? 35 PHE A N 1 +ATOM 252 C CA . PHE A 1 35 ? 18.786 -17.425 7.965 1.00 85.40 ? 35 PHE A CA 1 +ATOM 253 C C . PHE A 1 35 ? 18.569 -18.029 9.333 1.00 62.12 ? 35 PHE A C 1 +ATOM 254 O O . PHE A 1 35 ? 17.636 -17.623 10.035 1.00 94.21 ? 35 PHE A O 1 +ATOM 255 C CB . PHE A 1 35 ? 19.056 -15.921 8.163 1.00 94.08 ? 35 PHE A CB 1 +ATOM 256 C CG . PHE A 1 35 ? 19.887 -15.275 7.081 1.00 93.49 ? 35 PHE A CG 1 +ATOM 257 C CD1 . PHE A 1 35 ? 21.001 -15.903 6.552 1.00 70.44 ? 35 PHE A CD1 1 +ATOM 258 C CD2 . PHE A 1 35 ? 19.571 -13.991 6.639 1.00 99.97 ? 35 PHE A CD2 1 +ATOM 259 C CE1 . PHE A 1 35 ? 21.717 -15.314 5.535 1.00 59.05 ? 35 PHE A CE1 1 +ATOM 260 C CE2 . PHE A 1 35 ? 20.308 -13.387 5.634 1.00 80.33 ? 35 PHE A CE2 1 +ATOM 261 C CZ . PHE A 1 35 ? 21.403 -14.041 5.106 1.00 65.23 ? 35 PHE A CZ 1 +ATOM 262 N N . VAL A 1 36 ? 19.408 -18.962 9.713 1.00 45.01 ? 36 VAL A N 1 +ATOM 263 C CA . VAL A 1 36 ? 19.227 -19.611 10.989 1.00 47.04 ? 36 VAL A CA 1 +ATOM 264 C C . VAL A 1 36 ? 20.494 -19.638 11.872 1.00 56.02 ? 36 VAL A C 1 +ATOM 265 O O . VAL A 1 36 ? 21.619 -19.595 11.371 1.00 81.92 ? 36 VAL A O 1 +ATOM 266 C CB . VAL A 1 36 ? 18.777 -21.024 10.755 1.00 43.55 ? 36 VAL A CB 1 +ATOM 267 C CG1 . VAL A 1 36 ? 19.932 -21.892 10.296 1.00 55.61 ? 36 VAL A CG1 1 +ATOM 268 C CG2 . VAL A 1 36 ? 18.197 -21.589 12.021 1.00 42.76 ? 36 VAL A CG2 1 +ATOM 269 N N . SER A 1 37 ? 20.309 -19.651 13.191 1.00 55.85 ? 37 SER A N 1 +ATOM 270 C CA . SER A 1 37 ? 21.433 -19.654 14.175 1.00 48.69 ? 37 SER A CA 1 +ATOM 271 C C . SER A 1 37 ? 21.337 -20.840 15.102 1.00 50.29 ? 37 SER A C 1 +ATOM 272 O O . SER A 1 37 ? 20.238 -21.178 15.542 1.00 83.88 ? 37 SER A O 1 +ATOM 273 C CB . SER A 1 37 ? 21.357 -18.444 15.070 1.00 33.50 ? 37 SER A CB 1 +ATOM 274 O OG . SER A 1 37 ? 21.752 -17.296 14.371 1.00 33.50 ? 37 SER A OG 1 +ATOM 275 N N . VAL A 1 38 ? 22.411 -21.587 15.245 1.00 44.12 ? 38 VAL A N 1 +ATOM 276 C CA . VAL A 1 38 ? 22.383 -22.666 16.213 1.00 49.68 ? 38 VAL A CA 1 +ATOM 277 C C . VAL A 1 38 ? 23.530 -22.431 17.162 1.00 70.67 ? 38 VAL A C 1 +ATOM 278 O O . VAL A 1 38 ? 24.709 -22.408 16.726 1.00 126.96 ? 38 VAL A O 1 +ATOM 279 C CB . VAL A 1 38 ? 22.581 -24.074 15.602 1.00 57.41 ? 38 VAL A CB 1 +ATOM 280 C CG1 . VAL A 1 38 ? 22.669 -25.104 16.725 1.00 56.27 ? 38 VAL A CG1 1 +ATOM 281 C CG2 . VAL A 1 38 ? 21.483 -24.457 14.615 1.00 51.38 ? 38 VAL A CG2 1 +ATOM 282 N N . TYR A 1 39 ? 23.207 -22.243 18.443 1.00 62.58 ? 39 TYR A N 1 +ATOM 283 C CA . TYR A 1 39 ? 24.212 -21.898 19.464 1.00 48.07 ? 39 TYR A CA 1 +ATOM 284 C C . TYR A 1 39 ? 24.701 -23.174 20.120 1.00 61.22 ? 39 TYR A C 1 +ATOM 285 O O . TYR A 1 39 ? 25.905 -23.454 20.138 1.00 106.09 ? 39 TYR A O 1 +ATOM 286 C CB . TYR A 1 39 ? 23.647 -20.931 20.477 1.00 38.83 ? 39 TYR A CB 1 +ATOM 287 C CG . TYR A 1 39 ? 23.787 -19.512 20.052 1.00 38.73 ? 39 TYR A CG 1 +ATOM 288 C CD1 . TYR A 1 39 ? 22.894 -18.937 19.160 1.00 40.92 ? 39 TYR A CD1 1 +ATOM 289 C CD2 . TYR A 1 39 ? 24.780 -18.697 20.610 1.00 56.90 ? 39 TYR A CD2 1 +ATOM 290 C CE1 . TYR A 1 39 ? 23.007 -17.605 18.796 1.00 60.48 ? 39 TYR A CE1 1 +ATOM 291 C CE2 . TYR A 1 39 ? 24.903 -17.346 20.268 1.00 59.25 ? 39 TYR A CE2 1 +ATOM 292 C CZ . TYR A 1 39 ? 24.022 -16.792 19.378 1.00 62.30 ? 39 TYR A CZ 1 +ATOM 293 O OH . TYR A 1 39 ? 24.141 -15.466 19.013 1.00 40.69 ? 39 TYR A OH 1 +ATOM 294 N N . ASN A 1 40 ? 23.778 -24.036 20.521 1.00 66.72 ? 40 ASN A N 1 +ATOM 295 C CA . ASN A 1 40 ? 24.171 -25.275 21.170 1.00 74.91 ? 40 ASN A CA 1 +ATOM 296 C C . ASN A 1 40 ? 23.018 -26.256 21.359 1.00 81.00 ? 40 ASN A C 1 +ATOM 297 O O . ASN A 1 40 ? 21.962 -25.896 21.883 1.00 91.07 ? 40 ASN A O 1 +ATOM 298 C CB . ASN A 1 40 ? 24.805 -24.978 22.532 1.00 76.04 ? 40 ASN A CB 1 +ATOM 299 C CG . ASN A 1 40 ? 25.637 -26.132 23.041 1.00 107.42 ? 40 ASN A CG 1 +ATOM 300 O OD1 . ASN A 1 40 ? 26.605 -26.588 22.394 1.00 122.75 ? 40 ASN A OD1 1 +ATOM 301 N ND2 . ASN A 1 40 ? 25.297 -26.588 24.231 1.00 116.47 ? 40 ASN A ND2 1 +ATOM 302 N N . ILE A 1 41 ? 23.259 -27.514 21.012 1.00 83.98 ? 41 ILE A N 1 +ATOM 303 C CA . ILE A 1 41 ? 22.373 -28.596 21.397 1.00 90.07 ? 41 ILE A CA 1 +ATOM 304 C C . ILE A 1 41 ? 23.132 -29.551 22.350 1.00 94.69 ? 41 ILE A C 1 +ATOM 305 O O . ILE A 1 41 ? 24.091 -30.212 21.934 1.00 92.13 ? 41 ILE A O 1 +ATOM 306 C CB . ILE A 1 41 ? 21.836 -29.363 20.160 1.00 87.33 ? 41 ILE A CB 1 +ATOM 307 C CG1 . ILE A 1 41 ? 20.680 -28.613 19.499 1.00 67.22 ? 41 ILE A CG1 1 +ATOM 308 C CG2 . ILE A 1 41 ? 21.285 -30.727 20.569 1.00 90.72 ? 41 ILE A CG2 1 +ATOM 309 C CD1 . ILE A 1 41 ? 21.087 -27.349 18.794 1.00 75.75 ? 41 ILE A CD1 1 +ATOM 310 N N . GLN A 1 42 ? 22.659 -29.672 23.602 1.00 77.75 ? 42 GLN A N 1 +ATOM 311 C CA . GLN A 1 42 ? 23.391 -30.407 24.642 1.00 72.01 ? 42 GLN A CA 1 +ATOM 312 C C . GLN A 1 42 ? 23.076 -31.902 24.678 1.00 73.09 ? 42 GLN A C 1 +ATOM 313 O O . GLN A 1 42 ? 21.999 -32.325 24.264 1.00 62.78 ? 42 GLN A O 1 +ATOM 314 C CB . GLN A 1 42 ? 23.118 -29.815 26.018 1.00 79.73 ? 42 GLN A CB 1 +ATOM 315 C CG . GLN A 1 42 ? 23.658 -28.407 26.204 1.00 104.00 ? 42 GLN A CG 1 +ATOM 316 C CD . GLN A 1 42 ? 22.671 -27.344 26.661 1.00 126.47 ? 42 GLN A CD 1 +ATOM 317 O OE1 . GLN A 1 42 ? 22.402 -26.404 25.918 1.00 115.93 ? 42 GLN A OE1 1 +ATOM 318 N NE2 . GLN A 1 42 ? 22.288 -27.377 27.947 1.00 128.11 ? 42 GLN A NE2 1 +ATOM 319 N N . ASP A 1 43 ? 24.037 -32.689 25.173 1.00 75.91 ? 43 ASP A N 1 +ATOM 320 C CA . ASP A 1 43 ? 23.803 -34.065 25.557 1.00 76.94 ? 43 ASP A CA 1 +ATOM 321 C C . ASP A 1 43 ? 23.080 -34.113 26.924 1.00 80.27 ? 43 ASP A C 1 +ATOM 322 O O . ASP A 1 43 ? 23.603 -34.657 27.888 1.00 76.66 ? 43 ASP A O 1 +ATOM 323 C CB . ASP A 1 43 ? 25.124 -34.821 25.656 1.00 81.42 ? 43 ASP A CB 1 +ATOM 324 C CG . ASP A 1 43 ? 24.929 -36.343 25.806 1.00 115.72 ? 43 ASP A CG 1 +ATOM 325 O OD1 . ASP A 1 43 ? 24.174 -36.933 25.006 1.00 132.49 ? 43 ASP A OD1 1 +ATOM 326 O OD2 . ASP A 1 43 ? 25.545 -36.983 26.700 1.00 132.16 ? 43 ASP A OD2 1 +ATOM 327 N N . GLU A 1 44 ? 21.830 -33.632 26.967 1.00 87.21 ? 44 GLU A N 1 +ATOM 328 C CA . GLU A 1 44 ? 21.013 -33.613 28.212 1.00 64.85 ? 44 GLU A CA 1 +ATOM 329 C C . GLU A 1 44 ? 20.635 -35.033 28.704 1.00 64.56 ? 44 GLU A C 1 +ATOM 330 O O . GLU A 1 44 ? 19.708 -35.196 29.498 1.00 66.86 ? 44 GLU A O 1 +ATOM 331 C CB . GLU A 1 44 ? 19.754 -32.728 28.005 1.00 66.31 ? 44 GLU A CB 1 +ATOM 332 C CG . GLU A 1 44 ? 19.948 -31.247 28.289 1.00 62.33 ? 44 GLU A CG 1 +ATOM 333 C CD . GLU A 1 44 ? 18.698 -30.369 28.036 1.00 68.13 ? 44 GLU A CD 1 +ATOM 334 O OE1 . GLU A 1 44 ? 17.558 -30.735 28.423 1.00 81.11 ? 44 GLU A OE1 1 +ATOM 335 O OE2 . GLU A 1 44 ? 18.840 -29.261 27.453 1.00 73.38 ? 44 GLU A OE2 1 +ATOM 336 N N . THR A 1 45 ? 21.258 -36.060 28.107 1.00 62.16 ? 45 THR A N 1 +ATOM 337 C CA . THR A 1 45 ? 20.806 -37.446 28.248 1.00 78.63 ? 45 THR A CA 1 +ATOM 338 C C . THR A 1 45 ? 21.103 -37.967 29.650 1.00 85.48 ? 45 THR A C 1 +ATOM 339 O O . THR A 1 45 ? 20.322 -38.752 30.192 1.00 76.70 ? 45 THR A O 1 +ATOM 340 C CB . THR A 1 45 ? 21.339 -38.397 27.101 1.00 81.84 ? 45 THR A CB 1 +ATOM 341 O OG1 . THR A 1 45 ? 20.657 -39.659 27.144 1.00 86.28 ? 45 THR A OG1 1 +ATOM 342 C CG2 . THR A 1 45 ? 22.821 -38.660 27.222 1.00 108.02 ? 45 THR A CG2 1 +ATOM 343 N N . GLY A 1 46 ? 22.299 -37.675 30.151 1.00 94.15 ? 46 GLY A N 1 +ATOM 344 C CA . GLY A 1 46 ? 22.685 -38.088 31.512 1.00 97.21 ? 46 GLY A CA 1 +ATOM 345 C C . GLY A 1 46 ? 23.356 -39.463 31.611 1.00 90.97 ? 46 GLY A C 1 +ATOM 346 O O . GLY A 1 46 ? 23.390 -40.127 32.662 1.00 44.71 ? 46 GLY A O 1 +ATOM 347 N N . GLN A 1 47 ? 23.871 -39.933 30.494 1.00 85.39 ? 47 GLN A N 1 +ATOM 348 C CA . GLN A 1 47 ? 24.100 -41.328 30.403 1.00 70.23 ? 47 GLN A CA 1 +ATOM 349 C C . GLN A 1 47 ? 25.477 -41.621 29.884 1.00 63.29 ? 47 GLN A C 1 +ATOM 350 O O . GLN A 1 47 ? 25.985 -40.973 28.951 1.00 50.14 ? 47 GLN A O 1 +ATOM 351 C CB . GLN A 1 47 ? 23.041 -41.952 29.534 1.00 62.62 ? 47 GLN A CB 1 +ATOM 352 C CG . GLN A 1 47 ? 21.688 -41.943 30.195 1.00 74.72 ? 47 GLN A CG 1 +ATOM 353 C CD . GLN A 1 47 ? 21.747 -42.472 31.627 1.00 89.96 ? 47 GLN A CD 1 +ATOM 354 O OE1 . GLN A 1 47 ? 21.831 -43.675 31.836 1.00 98.89 ? 47 GLN A OE1 1 +ATOM 355 N NE2 . GLN A 1 47 ? 21.566 -41.589 32.601 1.00 69.89 ? 47 GLN A NE2 1 +ATOM 356 N N . PHE A 1 48 ? 26.084 -42.611 30.534 1.00 52.70 ? 48 PHE A N 1 +ATOM 357 C CA . PHE A 1 48 ? 27.391 -43.102 30.159 1.00 50.43 ? 48 PHE A CA 1 +ATOM 358 C C . PHE A 1 48 ? 27.346 -44.605 29.894 1.00 69.69 ? 48 PHE A C 1 +ATOM 359 O O . PHE A 1 48 ? 26.375 -45.312 30.225 1.00 58.24 ? 48 PHE A O 1 +ATOM 360 C CB . PHE A 1 48 ? 28.378 -42.826 31.266 1.00 48.93 ? 48 PHE A CB 1 +ATOM 361 C CG . PHE A 1 48 ? 28.602 -41.388 31.484 1.00 42.23 ? 48 PHE A CG 1 +ATOM 362 C CD1 . PHE A 1 48 ? 27.643 -40.622 32.170 1.00 39.16 ? 48 PHE A CD1 1 +ATOM 363 C CD2 . PHE A 1 48 ? 29.713 -40.804 30.992 1.00 39.24 ? 48 PHE A CD2 1 +ATOM 364 C CE1 . PHE A 1 48 ? 27.776 -39.273 32.337 1.00 36.86 ? 48 PHE A CE1 1 +ATOM 365 C CE2 . PHE A 1 48 ? 29.857 -39.458 31.133 1.00 50.15 ? 48 PHE A CE2 1 +ATOM 366 C CZ . PHE A 1 48 ? 28.883 -38.686 31.791 1.00 47.77 ? 48 PHE A CZ 1 +ATOM 367 N N . LYS A 1 49 ? 28.428 -45.093 29.292 1.00 90.13 ? 49 LYS A N 1 +ATOM 368 C CA . LYS A 1 49 ? 28.518 -46.493 28.893 1.00 86.20 ? 49 LYS A CA 1 +ATOM 369 C C . LYS A 1 49 ? 28.823 -47.345 30.110 1.00 84.06 ? 49 LYS A C 1 +ATOM 370 O O . LYS A 1 49 ? 29.512 -46.886 31.034 1.00 75.79 ? 49 LYS A O 1 +ATOM 371 C CB . LYS A 1 49 ? 29.575 -46.682 27.800 1.00 83.96 ? 49 LYS A CB 1 +ATOM 372 C CG . LYS A 1 49 ? 29.202 -45.987 26.496 1.00 89.37 ? 49 LYS A CG 1 +ATOM 373 C CD . LYS A 1 49 ? 30.070 -46.287 25.279 1.00 88.60 ? 49 LYS A CD 1 +ATOM 374 C CE . LYS A 1 49 ? 29.394 -45.645 24.059 1.00 89.62 ? 49 LYS A CE 1 +ATOM 375 N NZ . LYS A 1 49 ? 30.049 -45.874 22.748 1.00 76.62 ? 49 LYS A NZ 1 +ATOM 376 N N . PRO A 1 50 ? 28.245 -48.553 30.145 1.00 86.34 ? 50 PRO A N 1 +ATOM 377 C CA . PRO A 1 50 ? 28.442 -49.485 31.239 1.00 89.04 ? 50 PRO A CA 1 +ATOM 378 C C . PRO A 1 50 ? 29.754 -50.234 31.113 1.00 86.14 ? 50 PRO A C 1 +ATOM 379 O O . PRO A 1 50 ? 30.470 -50.120 30.082 1.00 94.39 ? 50 PRO A O 1 +ATOM 380 C CB . PRO A 1 50 ? 27.287 -50.460 31.085 1.00 95.28 ? 50 PRO A CB 1 +ATOM 381 C CG . PRO A 1 50 ? 26.983 -50.444 29.629 1.00 104.14 ? 50 PRO A CG 1 +ATOM 382 C CD . PRO A 1 50 ? 27.284 -49.057 29.150 1.00 95.17 ? 50 PRO A CD 1 +ATOM 383 N N . TYR A 1 51 ? 30.115 -50.932 32.183 1.00 77.86 ? 51 TYR A N 1 +ATOM 384 C CA . TYR A 1 51 ? 31.317 -51.753 32.150 1.00 91.51 ? 51 TYR A CA 1 +ATOM 385 C C . TYR A 1 51 ? 31.229 -52.658 30.936 1.00 94.76 ? 51 TYR A C 1 +ATOM 386 O O . TYR A 1 51 ? 30.160 -53.194 30.658 1.00 79.88 ? 51 TYR A O 1 +ATOM 387 C CB . TYR A 1 51 ? 31.428 -52.595 33.418 1.00 93.35 ? 51 TYR A CB 1 +ATOM 388 C CG . TYR A 1 51 ? 32.784 -53.233 33.553 1.00 99.81 ? 51 TYR A CG 1 +ATOM 389 C CD1 . TYR A 1 51 ? 33.827 -52.539 34.155 1.00 112.91 ? 51 TYR A CD1 1 +ATOM 390 C CD2 . TYR A 1 51 ? 33.037 -54.509 33.077 1.00 107.79 ? 51 TYR A CD2 1 +ATOM 391 C CE1 . TYR A 1 51 ? 35.094 -53.077 34.256 1.00 115.53 ? 51 TYR A CE1 1 +ATOM 392 C CE2 . TYR A 1 51 ? 34.308 -55.075 33.204 1.00 135.33 ? 51 TYR A CE2 1 +ATOM 393 C CZ . TYR A 1 51 ? 35.341 -54.327 33.761 1.00 131.98 ? 51 TYR A CZ 1 +ATOM 394 O OH . TYR A 1 51 ? 36.622 -54.821 33.907 1.00 148.14 ? 51 TYR A OH 1 +ATOM 395 N N . PRO A 1 52 ? 32.345 -52.828 30.197 1.00 100.36 ? 52 PRO A N 1 +ATOM 396 C CA . PRO A 1 52 ? 33.725 -52.388 30.459 1.00 90.98 ? 52 PRO A CA 1 +ATOM 397 C C . PRO A 1 52 ? 34.175 -51.062 29.854 1.00 91.55 ? 52 PRO A C 1 +ATOM 398 O O . PRO A 1 52 ? 35.377 -50.819 29.774 1.00 103.49 ? 52 PRO A O 1 +ATOM 399 C CB . PRO A 1 52 ? 34.545 -53.500 29.822 1.00 109.98 ? 52 PRO A CB 1 +ATOM 400 C CG . PRO A 1 52 ? 33.725 -53.903 28.631 1.00 124.77 ? 52 PRO A CG 1 +ATOM 401 C CD . PRO A 1 52 ? 32.283 -53.748 29.041 1.00 107.96 ? 52 PRO A CD 1 +ATOM 402 N N . ALA A 1 53 ? 33.245 -50.197 29.469 1.00 104.36 ? 53 ALA A N 1 +ATOM 403 C CA . ALA A 1 53 ? 33.635 -48.870 28.984 1.00 105.31 ? 53 ALA A CA 1 +ATOM 404 C C . ALA A 1 53 ? 34.310 -48.044 30.076 1.00 97.76 ? 53 ALA A C 1 +ATOM 405 O O . ALA A 1 53 ? 34.175 -48.339 31.288 1.00 73.91 ? 53 ALA A O 1 +ATOM 406 C CB . ALA A 1 53 ? 32.435 -48.118 28.455 1.00 97.65 ? 53 ALA A CB 1 +ATOM 407 N N . SER A 1 54 ? 35.046 -47.016 29.652 1.00 87.02 ? 54 SER A N 1 +ATOM 408 C CA . SER A 1 54 ? 35.527 -46.034 30.609 1.00 86.91 ? 54 SER A CA 1 +ATOM 409 C C . SER A 1 54 ? 34.307 -45.422 31.307 1.00 90.52 ? 54 SER A C 1 +ATOM 410 O O . SER A 1 54 ? 33.263 -45.190 30.710 1.00 57.83 ? 54 SER A O 1 +ATOM 411 C CB . SER A 1 54 ? 36.396 -44.936 29.967 1.00 67.49 ? 54 SER A CB 1 +ATOM 412 O OG . SER A 1 54 ? 36.436 -43.759 30.774 1.00 40.70 ? 54 SER A OG 1 +ATOM 413 N N . ASN A 1 55 ? 34.471 -45.166 32.599 1.00 86.08 ? 55 ASN A N 1 +ATOM 414 C CA . ASN A 1 55 ? 33.456 -44.509 33.396 1.00 59.79 ? 55 ASN A CA 1 +ATOM 415 C C . ASN A 1 55 ? 32.950 -43.249 32.724 1.00 64.02 ? 55 ASN A C 1 +ATOM 416 O O . ASN A 1 55 ? 31.812 -42.824 32.898 1.00 43.56 ? 55 ASN A O 1 +ATOM 417 C CB . ASN A 1 55 ? 34.066 -44.162 34.735 1.00 53.47 ? 55 ASN A CB 1 +ATOM 418 C CG . ASN A 1 55 ? 33.030 -43.824 35.750 1.00 67.57 ? 55 ASN A CG 1 +ATOM 419 O OD1 . ASN A 1 55 ? 31.858 -44.184 35.632 1.00 104.60 ? 55 ASN A OD1 1 +ATOM 420 N ND2 . ASN A 1 55 ? 33.465 -43.189 36.800 1.00 76.63 ? 55 ASN A ND2 1 +ATOM 421 N N . PHE A 1 56 ? 33.847 -42.624 31.956 1.00 83.94 ? 56 PHE A N 1 +ATOM 422 C CA . PHE A 1 56 ? 33.614 -41.282 31.391 1.00 72.92 ? 56 PHE A CA 1 +ATOM 423 C C . PHE A 1 56 ? 33.106 -41.316 29.962 1.00 68.66 ? 56 PHE A C 1 +ATOM 424 O O . PHE A 1 56 ? 32.973 -40.273 29.335 1.00 59.86 ? 56 PHE A O 1 +ATOM 425 C CB . PHE A 1 56 ? 34.897 -40.469 31.395 1.00 61.93 ? 56 PHE A CB 1 +ATOM 426 C CG . PHE A 1 56 ? 35.474 -40.295 32.746 1.00 63.89 ? 56 PHE A CG 1 +ATOM 427 C CD1 . PHE A 1 56 ? 34.779 -39.674 33.753 1.00 64.11 ? 56 PHE A CD1 1 +ATOM 428 C CD2 . PHE A 1 56 ? 36.704 -40.825 33.017 1.00 100.39 ? 56 PHE A CD2 1 +ATOM 429 C CE1 . PHE A 1 56 ? 35.311 -39.562 35.009 1.00 79.28 ? 56 PHE A CE1 1 +ATOM 430 C CE2 . PHE A 1 56 ? 37.281 -40.661 34.263 1.00 119.27 ? 56 PHE A CE2 1 +ATOM 431 C CZ . PHE A 1 56 ? 36.571 -40.044 35.267 1.00 106.83 ? 56 PHE A CZ 1 +ATOM 432 N N . SER A 1 57 ? 32.960 -42.505 29.396 1.00 72.64 ? 57 SER A N 1 +ATOM 433 C CA . SER A 1 57 ? 32.509 -42.600 28.016 1.00 87.28 ? 57 SER A CA 1 +ATOM 434 C C . SER A 1 57 ? 31.005 -42.330 27.975 1.00 88.62 ? 57 SER A C 1 +ATOM 435 O O . SER A 1 57 ? 30.212 -43.060 28.555 1.00 71.93 ? 57 SER A O 1 +ATOM 436 C CB . SER A 1 57 ? 32.846 -43.975 27.418 1.00 112.34 ? 57 SER A CB 1 +ATOM 437 O OG . SER A 1 57 ? 34.231 -44.067 27.117 1.00 116.79 ? 57 SER A OG 1 +ATOM 438 N N . THR A 1 58 ? 30.633 -41.240 27.328 1.00 93.73 ? 58 THR A N 1 +ATOM 439 C CA . THR A 1 58 ? 29.248 -40.868 27.236 1.00 80.95 ? 58 THR A CA 1 +ATOM 440 C C . THR A 1 58 ? 28.537 -41.784 26.327 1.00 81.57 ? 58 THR A C 1 +ATOM 441 O O . THR A 1 58 ? 29.087 -42.363 25.387 1.00 106.08 ? 58 THR A O 1 +ATOM 442 C CB . THR A 1 58 ? 29.092 -39.480 26.643 1.00 96.64 ? 58 THR A CB 1 +ATOM 443 O OG1 . THR A 1 58 ? 29.670 -39.429 25.333 1.00 88.40 ? 58 THR A OG1 1 +ATOM 444 C CG2 . THR A 1 58 ? 29.825 -38.493 27.504 1.00 137.80 ? 58 THR A CG2 1 +ATOM 445 N N . ALA A 1 59 ? 27.264 -41.914 26.552 1.00 93.85 ? 59 ALA A N 1 +ATOM 446 C CA . ALA A 1 59 ? 26.564 -42.884 25.741 1.00 98.58 ? 59 ALA A CA 1 +ATOM 447 C C . ALA A 1 59 ? 26.326 -42.324 24.349 1.00 73.16 ? 59 ALA A C 1 +ATOM 448 O O . ALA A 1 59 ? 26.001 -43.054 23.431 1.00 66.16 ? 59 ALA A O 1 +ATOM 449 C CB . ALA A 1 59 ? 25.282 -43.304 26.423 1.00 98.98 ? 59 ALA A CB 1 +ATOM 450 N N . VAL A 1 60 ? 26.425 -41.007 24.230 1.00 69.09 ? 60 VAL A N 1 +ATOM 451 C CA . VAL A 1 60 ? 25.963 -40.298 23.044 1.00 72.04 ? 60 VAL A CA 1 +ATOM 452 C C . VAL A 1 60 ? 27.014 -39.250 22.696 1.00 54.62 ? 60 VAL A C 1 +ATOM 453 O O . VAL A 1 60 ? 27.559 -38.620 23.580 1.00 49.58 ? 60 VAL A O 1 +ATOM 454 C CB . VAL A 1 60 ? 24.604 -39.572 23.310 1.00 97.26 ? 60 VAL A CB 1 +ATOM 455 C CG1 . VAL A 1 60 ? 24.139 -38.799 22.083 1.00 102.04 ? 60 VAL A CG1 1 +ATOM 456 C CG2 . VAL A 1 60 ? 23.518 -40.557 23.749 1.00 107.45 ? 60 VAL A CG2 1 +ATOM 457 N N . PRO A 1 61 ? 27.270 -39.046 21.406 1.00 41.27 ? 61 PRO A N 1 +ATOM 458 C CA . PRO A 1 61 ? 28.339 -38.139 21.046 1.00 32.04 ? 61 PRO A CA 1 +ATOM 459 C C . PRO A 1 61 ? 27.939 -36.765 21.330 1.00 34.85 ? 61 PRO A C 1 +ATOM 460 O O . PRO A 1 61 ? 26.727 -36.400 21.214 1.00 35.22 ? 61 PRO A O 1 +ATOM 461 C CB . PRO A 1 61 ? 28.483 -38.336 19.546 1.00 35.24 ? 61 PRO A CB 1 +ATOM 462 C CG . PRO A 1 61 ? 27.197 -39.025 19.102 1.00 44.03 ? 61 PRO A CG 1 +ATOM 463 C CD . PRO A 1 61 ? 26.814 -39.876 20.262 1.00 46.32 ? 61 PRO A CD 1 +ATOM 464 N N . GLN A 1 62 ? 28.935 -35.954 21.677 1.00 50.69 ? 62 GLN A N 1 +ATOM 465 C CA . GLN A 1 62 ? 28.688 -34.569 22.105 1.00 67.74 ? 62 GLN A CA 1 +ATOM 466 C C . GLN A 1 62 ? 28.705 -33.634 20.929 1.00 50.34 ? 62 GLN A C 1 +ATOM 467 O O . GLN A 1 62 ? 29.109 -32.517 21.062 1.00 51.30 ? 62 GLN A O 1 +ATOM 468 C CB . GLN A 1 62 ? 29.749 -34.112 23.123 1.00 82.24 ? 62 GLN A CB 1 +ATOM 469 C CG . GLN A 1 62 ? 29.975 -35.072 24.293 1.00 95.42 ? 62 GLN A CG 1 +ATOM 470 C CD . GLN A 1 62 ? 28.721 -35.321 25.109 1.00 103.08 ? 62 GLN A CD 1 +ATOM 471 O OE1 . GLN A 1 62 ? 28.297 -34.475 25.900 1.00 102.18 ? 62 GLN A OE1 1 +ATOM 472 N NE2 . GLN A 1 62 ? 28.076 -36.455 24.864 1.00 94.55 ? 62 GLN A NE2 1 +ATOM 473 N N . SER A 1 63 ? 28.124 -34.056 19.823 1.00 64.08 ? 63 SER A N 1 +ATOM 474 C CA . SER A 1 63 ? 28.377 -33.419 18.540 1.00 78.16 ? 63 SER A CA 1 +ATOM 475 C C . SER A 1 63 ? 27.089 -33.006 17.837 1.00 96.90 ? 63 SER A C 1 +ATOM 476 O O . SER A 1 63 ? 27.101 -32.576 16.682 1.00 77.84 ? 63 SER A O 1 +ATOM 477 C CB . SER A 1 63 ? 29.196 -34.364 17.639 1.00 83.70 ? 63 SER A CB 1 +ATOM 478 O OG . SER A 1 63 ? 28.529 -35.577 17.345 1.00 47.35 ? 63 SER A OG 1 +ATOM 479 N N . ALA A 1 64 ? 25.986 -33.077 18.573 1.00 120.52 ? 64 ALA A N 1 +ATOM 480 C CA . ALA A 1 64 ? 24.667 -32.859 17.993 1.00 131.01 ? 64 ALA A CA 1 +ATOM 481 C C . ALA A 1 64 ? 24.559 -31.492 17.278 1.00 111.27 ? 64 ALA A C 1 +ATOM 482 O O . ALA A 1 64 ? 23.886 -31.359 16.242 1.00 92.65 ? 64 ALA A O 1 +ATOM 483 C CB . ALA A 1 64 ? 23.612 -33.002 19.085 1.00 134.13 ? 64 ALA A CB 1 +ATOM 484 N N . THR A 1 65 ? 25.158 -30.468 17.883 1.00 81.32 ? 65 THR A N 1 +ATOM 485 C CA . THR A 1 65 ? 25.061 -29.092 17.390 1.00 64.82 ? 65 THR A CA 1 +ATOM 486 C C . THR A 1 65 ? 25.516 -28.982 15.959 1.00 54.59 ? 65 THR A C 1 +ATOM 487 O O . THR A 1 65 ? 24.812 -28.426 15.115 1.00 88.96 ? 65 THR A O 1 +ATOM 488 C CB . THR A 1 65 ? 25.979 -28.206 18.202 1.00 83.61 ? 65 THR A CB 1 +ATOM 489 O OG1 . THR A 1 65 ? 25.913 -28.593 19.584 1.00 97.97 ? 65 THR A OG1 1 +ATOM 490 C CG2 . THR A 1 65 ? 25.622 -26.736 18.026 1.00 75.64 ? 65 THR A CG2 1 +ATOM 491 N N . ALA A 1 66 ? 26.643 -29.598 15.662 1.00 50.99 ? 66 ALA A N 1 +ATOM 492 C CA . ALA A 1 66 ? 27.192 -29.516 14.344 1.00 68.72 ? 66 ALA A CA 1 +ATOM 493 C C . ALA A 1 66 ? 26.361 -30.348 13.349 1.00 82.20 ? 66 ALA A C 1 +ATOM 494 O O . ALA A 1 66 ? 26.214 -29.963 12.166 1.00 111.38 ? 66 ALA A O 1 +ATOM 495 C CB . ALA A 1 66 ? 28.634 -29.981 14.362 1.00 94.48 ? 66 ALA A CB 1 +ATOM 496 N N . MET A 1 67 ? 25.819 -31.474 13.816 1.00 70.56 ? 67 MET A N 1 +ATOM 497 C CA . MET A 1 67 ? 24.953 -32.309 12.964 1.00 72.97 ? 67 MET A CA 1 +ATOM 498 C C . MET A 1 67 ? 23.717 -31.516 12.542 1.00 55.93 ? 67 MET A C 1 +ATOM 499 O O . MET A 1 67 ? 23.245 -31.591 11.425 1.00 48.96 ? 67 MET A O 1 +ATOM 500 C CB . MET A 1 67 ? 24.530 -33.583 13.714 1.00 86.00 ? 67 MET A CB 1 +ATOM 501 C CG . MET A 1 67 ? 25.629 -34.613 13.940 1.00 91.95 ? 67 MET A CG 1 +ATOM 502 S SD . MET A 1 67 ? 25.121 -35.904 15.109 1.00 69.69 ? 67 MET A SD 1 +ATOM 503 C CE . MET A 1 67 ? 26.494 -37.035 15.020 1.00 94.40 ? 67 MET A CE 1 +ATOM 504 N N . LEU A 1 68 ? 23.156 -30.781 13.489 1.00 51.98 ? 68 LEU A N 1 +ATOM 505 C CA . LEU A 1 68 ? 21.958 -30.022 13.217 1.00 49.20 ? 68 LEU A CA 1 +ATOM 506 C C . LEU A 1 68 ? 22.285 -28.993 12.176 1.00 50.73 ? 68 LEU A C 1 +ATOM 507 O O . LEU A 1 68 ? 21.454 -28.710 11.323 1.00 74.80 ? 68 LEU A O 1 +ATOM 508 C CB . LEU A 1 68 ? 21.386 -29.364 14.507 1.00 52.36 ? 68 LEU A CB 1 +ATOM 509 C CG . LEU A 1 68 ? 20.271 -28.350 14.241 1.00 57.51 ? 68 LEU A CG 1 +ATOM 510 C CD1 . LEU A 1 68 ? 19.035 -29.023 13.663 1.00 63.11 ? 68 LEU A CD1 1 +ATOM 511 C CD2 . LEU A 1 68 ? 19.891 -27.558 15.473 1.00 60.61 ? 68 LEU A CD2 1 +ATOM 512 N N . VAL A 1 69 ? 23.388 -28.271 12.365 1.00 63.67 ? 69 VAL A N 1 +ATOM 513 C CA . VAL A 1 69 ? 23.726 -27.145 11.473 1.00 70.52 ? 69 VAL A CA 1 +ATOM 514 C C . VAL A 1 69 ? 23.886 -27.724 10.077 1.00 57.27 ? 69 VAL A C 1 +ATOM 515 O O . VAL A 1 69 ? 23.406 -27.149 9.102 1.00 48.58 ? 69 VAL A O 1 +ATOM 516 C CB . VAL A 1 69 ? 25.034 -26.429 11.881 1.00 78.98 ? 69 VAL A CB 1 +ATOM 517 C CG1 . VAL A 1 69 ? 25.453 -25.462 10.795 1.00 82.20 ? 69 VAL A CG1 1 +ATOM 518 C CG2 . VAL A 1 69 ? 24.883 -25.677 13.194 1.00 84.42 ? 69 VAL A CG2 1 +ATOM 519 N N . THR A 1 70 ? 24.512 -28.893 10.010 1.00 46.30 ? 70 THR A N 1 +ATOM 520 C CA . THR A 1 70 ? 24.756 -29.527 8.744 1.00 63.94 ? 70 THR A CA 1 +ATOM 521 C C . THR A 1 70 ? 23.436 -29.955 8.098 1.00 72.48 ? 70 THR A C 1 +ATOM 522 O O . THR A 1 70 ? 23.218 -29.752 6.892 1.00 107.14 ? 70 THR A O 1 +ATOM 523 C CB . THR A 1 70 ? 25.660 -30.738 8.931 1.00 94.63 ? 70 THR A CB 1 +ATOM 524 O OG1 . THR A 1 70 ? 26.884 -30.316 9.546 1.00 108.27 ? 70 THR A OG1 1 +ATOM 525 C CG2 . THR A 1 70 ? 25.972 -31.400 7.573 1.00 125.72 ? 70 THR A CG2 1 +ATOM 526 N N . ALA A 1 71 ? 22.547 -30.545 8.883 1.00 58.17 ? 71 ALA A N 1 +ATOM 527 C CA . ALA A 1 71 ? 21.234 -30.942 8.357 1.00 45.54 ? 71 ALA A CA 1 +ATOM 528 C C . ALA A 1 71 ? 20.451 -29.704 7.852 1.00 43.59 ? 71 ALA A C 1 +ATOM 529 O O . ALA A 1 71 ? 19.782 -29.745 6.842 1.00 37.60 ? 71 ALA A O 1 +ATOM 530 C CB . ALA A 1 71 ? 20.444 -31.681 9.442 1.00 49.20 ? 71 ALA A CB 1 +ATOM 531 N N . LEU A 1 72 ? 20.479 -28.622 8.622 1.00 49.59 ? 72 LEU A N 1 +ATOM 532 C CA . LEU A 1 72 ? 19.811 -27.381 8.233 1.00 53.12 ? 72 LEU A CA 1 +ATOM 533 C C . LEU A 1 72 ? 20.360 -26.866 6.909 1.00 72.19 ? 72 LEU A C 1 +ATOM 534 O O . LEU A 1 72 ? 19.679 -26.145 6.205 1.00 74.86 ? 72 LEU A O 1 +ATOM 535 C CB . LEU A 1 72 ? 19.997 -26.300 9.307 1.00 55.35 ? 72 LEU A CB 1 +ATOM 536 C CG . LEU A 1 72 ? 19.278 -26.573 10.616 1.00 57.62 ? 72 LEU A CG 1 +ATOM 537 C CD1 . LEU A 1 72 ? 19.869 -25.679 11.706 1.00 74.57 ? 72 LEU A CD1 1 +ATOM 538 C CD2 . LEU A 1 72 ? 17.799 -26.340 10.499 1.00 62.11 ? 72 LEU A CD2 1 +ATOM 539 N N . LYS A 1 73 ? 21.620 -27.188 6.599 1.00 89.12 ? 73 LYS A N 1 +ATOM 540 C CA . LYS A 1 73 ? 22.236 -26.726 5.348 1.00 81.89 ? 73 LYS A CA 1 +ATOM 541 C C . LYS A 1 73 ? 21.894 -27.640 4.201 1.00 89.68 ? 73 LYS A C 1 +ATOM 542 O O . LYS A 1 73 ? 21.512 -27.171 3.132 1.00 110.88 ? 73 LYS A O 1 +ATOM 543 C CB . LYS A 1 73 ? 23.756 -26.641 5.456 1.00 81.84 ? 73 LYS A CB 1 +ATOM 544 C CG . LYS A 1 73 ? 24.401 -25.901 4.287 1.00 85.24 ? 73 LYS A CG 1 +ATOM 545 C CD . LYS A 1 73 ? 25.921 -25.832 4.433 1.00 101.49 ? 73 LYS A CD 1 +ATOM 546 C CE . LYS A 1 73 ? 26.620 -25.742 3.083 1.00 140.36 ? 73 LYS A CE 1 +ATOM 547 N NZ . LYS A 1 73 ? 27.311 -24.439 2.864 1.00 162.23 ? 73 LYS A NZ 1 +ATOM 548 N N . ASP A 1 74 ? 21.986 -28.950 4.436 1.00 91.51 ? 74 ASP A N 1 +ATOM 549 C CA . ASP A 1 74 ? 21.697 -29.946 3.390 1.00 109.24 ? 74 ASP A CA 1 +ATOM 550 C C . ASP A 1 74 ? 20.255 -29.883 2.871 1.00 109.57 ? 74 ASP A C 1 +ATOM 551 O O . ASP A 1 74 ? 20.007 -30.159 1.698 1.00 102.23 ? 74 ASP A O 1 +ATOM 552 C CB . ASP A 1 74 ? 21.962 -31.354 3.903 1.00 121.11 ? 74 ASP A CB 1 +ATOM 553 C CG . ASP A 1 74 ? 23.443 -31.623 4.170 1.00 136.63 ? 74 ASP A CG 1 +ATOM 554 O OD1 . ASP A 1 74 ? 24.329 -31.026 3.506 1.00 126.64 ? 74 ASP A OD1 1 +ATOM 555 O OD2 . ASP A 1 74 ? 23.709 -32.485 5.033 1.00 158.01 ? 74 ASP A OD2 1 +ATOM 556 N N . SER A 1 75 ? 19.337 -29.411 3.722 1.00 113.42 ? 75 SER A N 1 +ATOM 557 C CA . SER A 1 75 ? 17.919 -29.278 3.365 1.00 90.03 ? 75 SER A CA 1 +ATOM 558 C C . SER A 1 75 ? 17.656 -28.259 2.244 1.00 81.58 ? 75 SER A C 1 +ATOM 559 O O . SER A 1 75 ? 16.660 -28.365 1.531 1.00 76.72 ? 75 SER A O 1 +ATOM 560 C CB . SER A 1 75 ? 17.097 -28.871 4.590 1.00 80.03 ? 75 SER A CB 1 +ATOM 561 O OG . SER A 1 75 ? 17.070 -27.458 4.747 1.00 63.77 ? 75 SER A OG 1 +ATOM 562 N N . ARG A 1 76 ? 18.548 -27.275 2.120 1.00 59.34 ? 76 ARG A N 1 +ATOM 563 C CA . ARG A 1 76 ? 18.456 -26.218 1.127 1.00 56.63 ? 76 ARG A CA 1 +ATOM 564 C C . ARG A 1 76 ? 17.243 -25.376 1.413 1.00 54.76 ? 76 ARG A C 1 +ATOM 565 O O . ARG A 1 76 ? 16.610 -24.860 0.500 1.00 46.86 ? 76 ARG A O 1 +ATOM 566 C CB . ARG A 1 76 ? 18.415 -26.752 -0.314 1.00 59.53 ? 76 ARG A CB 1 +ATOM 567 C CG . ARG A 1 76 ? 19.693 -27.315 -0.871 1.00 69.97 ? 76 ARG A CG 1 +ATOM 568 C CD . ARG A 1 76 ? 20.841 -26.305 -0.852 1.00 114.97 ? 76 ARG A CD 1 +ATOM 569 N NE . ARG A 1 76 ? 20.662 -25.205 -1.815 1.00 136.41 ? 76 ARG A NE 1 +ATOM 570 C CZ . ARG A 1 76 ? 20.176 -23.982 -1.538 1.00 107.02 ? 76 ARG A CZ 1 +ATOM 571 N NH1 . ARG A 1 76 ? 19.767 -23.634 -0.316 1.00 82.72 ? 76 ARG A NH1 1 +ATOM 572 N NH2 . ARG A 1 76 ? 20.106 -23.088 -2.516 1.00 104.85 ? 76 ARG A NH2 1 +ATOM 573 N N . TRP A 1 77 ? 16.961 -25.210 2.693 1.00 63.47 ? 77 TRP A N 1 +ATOM 574 C CA . TRP A 1 77 ? 15.954 -24.263 3.154 1.00 80.07 ? 77 TRP A CA 1 +ATOM 575 C C . TRP A 1 77 ? 16.585 -23.127 3.989 1.00 82.83 ? 77 TRP A C 1 +ATOM 576 O O . TRP A 1 77 ? 16.128 -21.976 3.933 1.00 72.25 ? 77 TRP A O 1 +ATOM 577 C CB . TRP A 1 77 ? 14.922 -25.005 4.003 1.00 73.79 ? 77 TRP A CB 1 +ATOM 578 C CG . TRP A 1 77 ? 13.742 -25.527 3.238 1.00 70.96 ? 77 TRP A CG 1 +ATOM 579 C CD1 . TRP A 1 77 ? 13.701 -26.625 2.452 1.00 71.05 ? 77 TRP A CD1 1 +ATOM 580 C CD2 . TRP A 1 77 ? 12.420 -24.986 3.240 1.00 68.54 ? 77 TRP A CD2 1 +ATOM 581 N NE1 . TRP A 1 77 ? 12.444 -26.792 1.940 1.00 73.32 ? 77 TRP A NE1 1 +ATOM 582 C CE2 . TRP A 1 77 ? 11.645 -25.779 2.387 1.00 65.57 ? 77 TRP A CE2 1 +ATOM 583 C CE3 . TRP A 1 77 ? 11.832 -23.874 3.850 1.00 79.57 ? 77 TRP A CE3 1 +ATOM 584 C CZ2 . TRP A 1 77 ? 10.316 -25.500 2.114 1.00 69.27 ? 77 TRP A CZ2 1 +ATOM 585 C CZ3 . TRP A 1 77 ? 10.501 -23.615 3.610 1.00 84.82 ? 77 TRP A CZ3 1 +ATOM 586 C CH2 . TRP A 1 77 ? 9.756 -24.416 2.735 1.00 83.44 ? 77 TRP A CH2 1 +ATOM 587 N N . PHE A 1 78 ? 17.673 -23.456 4.685 1.00 77.63 ? 78 PHE A N 1 +ATOM 588 C CA . PHE A 1 78 ? 18.308 -22.549 5.626 1.00 73.30 ? 78 PHE A CA 1 +ATOM 589 C C . PHE A 1 78 ? 19.774 -22.288 5.317 1.00 66.29 ? 78 PHE A C 1 +ATOM 590 O O . PHE A 1 78 ? 20.496 -23.177 4.870 1.00 50.41 ? 78 PHE A O 1 +ATOM 591 C CB . PHE A 1 78 ? 18.262 -23.155 7.008 1.00 81.82 ? 78 PHE A CB 1 +ATOM 592 C CG . PHE A 1 78 ? 16.882 -23.532 7.452 1.00 79.89 ? 78 PHE A CG 1 +ATOM 593 C CD1 . PHE A 1 78 ? 15.985 -22.572 7.866 1.00 89.17 ? 78 PHE A CD1 1 +ATOM 594 C CD2 . PHE A 1 78 ? 16.508 -24.843 7.515 1.00 72.02 ? 78 PHE A CD2 1 +ATOM 595 C CE1 . PHE A 1 78 ? 14.728 -22.929 8.320 1.00 73.34 ? 78 PHE A CE1 1 +ATOM 596 C CE2 . PHE A 1 78 ? 15.251 -25.198 7.972 1.00 60.61 ? 78 PHE A CE2 1 +ATOM 597 C CZ . PHE A 1 78 ? 14.368 -24.246 8.386 1.00 52.83 ? 78 PHE A CZ 1 +ATOM 598 N N . ILE A 1 79 ? 20.198 -21.046 5.560 1.00 62.00 ? 79 ILE A N 1 +ATOM 599 C CA . ILE A 1 79 ? 21.602 -20.682 5.615 1.00 49.51 ? 79 ILE A CA 1 +ATOM 600 C C . ILE A 1 79 ? 21.950 -20.656 7.075 1.00 42.02 ? 79 ILE A C 1 +ATOM 601 O O . ILE A 1 79 ? 21.288 -19.947 7.871 1.00 64.78 ? 79 ILE A O 1 +ATOM 602 C CB . ILE A 1 79 ? 21.844 -19.269 5.057 1.00 56.65 ? 79 ILE A CB 1 +ATOM 603 C CG1 . ILE A 1 79 ? 21.198 -19.112 3.693 1.00 56.59 ? 79 ILE A CG1 1 +ATOM 604 C CG2 . ILE A 1 79 ? 23.343 -18.973 4.960 1.00 76.26 ? 79 ILE A CG2 1 +ATOM 605 C CD1 . ILE A 1 79 ? 20.906 -17.667 3.324 1.00 68.21 ? 79 ILE A CD1 1 +ATOM 606 N N . PRO A 1 80 ? 22.953 -21.430 7.447 1.00 30.98 ? 80 PRO A N 1 +ATOM 607 C CA . PRO A 1 80 ? 23.265 -21.336 8.837 1.00 39.18 ? 80 PRO A CA 1 +ATOM 608 C C . PRO A 1 80 ? 24.275 -20.229 9.057 1.00 42.38 ? 80 PRO A C 1 +ATOM 609 O O . PRO A 1 80 ? 25.309 -20.235 8.388 1.00 74.73 ? 80 PRO A O 1 +ATOM 610 C CB . PRO A 1 80 ? 23.806 -22.757 9.162 1.00 34.12 ? 80 PRO A CB 1 +ATOM 611 C CG . PRO A 1 80 ? 23.204 -23.623 8.152 1.00 27.11 ? 80 PRO A CG 1 +ATOM 612 C CD . PRO A 1 80 ? 23.276 -22.746 6.928 1.00 27.33 ? 80 PRO A CD 1 +ATOM 613 N N . LEU A 1 81 ? 24.039 -19.403 10.060 1.00 35.28 ? 81 LEU A N 1 +ATOM 614 C CA . LEU A 1 81 ? 25.054 -18.552 10.550 1.00 54.53 ? 81 LEU A CA 1 +ATOM 615 C C . LEU A 1 81 ? 25.896 -19.142 11.697 1.00 75.89 ? 81 LEU A C 1 +ATOM 616 O O . LEU A 1 81 ? 25.379 -19.912 12.543 1.00 74.47 ? 81 LEU A O 1 +ATOM 617 C CB . LEU A 1 81 ? 24.416 -17.281 11.004 1.00 62.31 ? 81 LEU A CB 1 +ATOM 618 C CG . LEU A 1 81 ? 23.523 -16.758 9.894 1.00 65.48 ? 81 LEU A CG 1 +ATOM 619 C CD1 . LEU A 1 81 ? 22.804 -15.543 10.438 1.00 86.99 ? 81 LEU A CD1 1 +ATOM 620 C CD2 . LEU A 1 81 ? 24.336 -16.370 8.693 1.00 73.15 ? 81 LEU A CD2 1 +ATOM 621 N N . GLU A 1 82 ? 27.208 -18.820 11.677 1.00 80.49 ? 82 GLU A N 1 +ATOM 622 C CA . GLU A 1 82 ? 28.176 -19.446 12.584 1.00 87.60 ? 82 GLU A CA 1 +ATOM 623 C C . GLU A 1 82 ? 28.114 -18.762 13.918 1.00 75.18 ? 82 GLU A C 1 +ATOM 624 O O . GLU A 1 82 ? 28.608 -17.640 14.073 1.00 77.21 ? 82 GLU A O 1 +ATOM 625 C CB . GLU A 1 82 ? 29.628 -19.462 12.026 1.00 88.56 ? 82 GLU A CB 1 +ATOM 626 C CG . GLU A 1 82 ? 30.695 -20.084 12.955 1.00 85.61 ? 82 GLU A CG 1 +ATOM 627 C CD . GLU A 1 82 ? 30.595 -21.616 13.149 1.00 108.95 ? 82 GLU A CD 1 +ATOM 628 O OE1 . GLU A 1 82 ? 29.485 -22.175 13.423 1.00 137.78 ? 82 GLU A OE1 1 +ATOM 629 O OE2 . GLU A 1 82 ? 31.649 -22.288 13.054 1.00 142.30 ? 82 GLU A OE2 1 +ATOM 630 N N . ARG A 1 83 ? 27.588 -19.508 14.898 1.00 73.94 ? 83 ARG A N 1 +ATOM 631 C CA . ARG A 1 83 ? 27.599 -19.090 16.289 1.00 72.17 ? 83 ARG A CA 1 +ATOM 632 C C . ARG A 1 83 ? 28.263 -20.099 17.241 1.00 70.14 ? 83 ARG A C 1 +ATOM 633 O O . ARG A 1 83 ? 28.692 -19.720 18.334 1.00 88.31 ? 83 ARG A O 1 +ATOM 634 C CB . ARG A 1 83 ? 26.182 -18.797 16.745 1.00 70.04 ? 83 ARG A CB 1 +ATOM 635 C CG . ARG A 1 83 ? 25.442 -17.785 15.880 1.00 69.81 ? 83 ARG A CG 1 +ATOM 636 C CD . ARG A 1 83 ? 25.991 -16.365 16.023 1.00 65.38 ? 83 ARG A CD 1 +ATOM 637 N NE . ARG A 1 83 ? 25.083 -15.417 15.370 1.00 54.39 ? 83 ARG A NE 1 +ATOM 638 C CZ . ARG A 1 83 ? 25.238 -14.920 14.150 1.00 58.08 ? 83 ARG A CZ 1 +ATOM 639 N NH1 . ARG A 1 83 ? 26.343 -15.160 13.449 1.00 75.59 ? 83 ARG A NH1 1 +ATOM 640 N NH2 . ARG A 1 83 ? 24.267 -14.211 13.617 1.00 55.08 ? 83 ARG A NH2 1 +ATOM 641 N N . GLN A 1 84 ? 28.418 -21.353 16.842 1.00 74.76 ? 84 GLN A N 1 +ATOM 642 C CA . GLN A 1 84 ? 29.112 -22.285 17.736 1.00 87.49 ? 84 GLN A CA 1 +ATOM 643 C C . GLN A 1 84 ? 30.509 -21.760 18.057 1.00 86.07 ? 84 GLN A C 1 +ATOM 644 O O . GLN A 1 84 ? 30.978 -21.841 19.186 1.00 99.06 ? 84 GLN A O 1 +ATOM 645 C CB . GLN A 1 84 ? 29.157 -23.718 17.181 1.00 86.80 ? 84 GLN A CB 1 +ATOM 646 C CG . GLN A 1 84 ? 29.144 -24.804 18.262 1.00 84.92 ? 84 GLN A CG 1 +ATOM 647 C CD . GLN A 1 84 ? 29.257 -26.209 17.691 1.00 125.73 ? 84 GLN A CD 1 +ATOM 648 O OE1 . GLN A 1 84 ? 28.744 -26.495 16.606 1.00 173.17 ? 84 GLN A OE1 1 +ATOM 649 N NE2 . GLN A 1 84 ? 29.938 -27.098 18.415 1.00 129.70 ? 84 GLN A NE2 1 +ATOM 650 N N . GLY A 1 85 ? 31.199 -21.236 17.060 1.00 85.15 ? 85 GLY A N 1 +ATOM 651 C CA . GLY A 1 85 ? 32.537 -20.749 17.312 1.00 79.51 ? 85 GLY A CA 1 +ATOM 652 C C . GLY A 1 85 ? 32.575 -19.247 17.156 1.00 55.63 ? 85 GLY A C 1 +ATOM 653 O O . GLY A 1 85 ? 33.602 -18.703 16.740 1.00 58.73 ? 85 GLY A O 1 +ATOM 654 N N . LEU A 1 86 ? 31.567 -18.580 17.695 1.00 45.93 ? 86 LEU A N 1 +ATOM 655 C CA . LEU A 1 86 ? 31.437 -17.137 17.529 1.00 52.64 ? 86 LEU A CA 1 +ATOM 656 C C . LEU A 1 86 ? 32.642 -16.346 18.062 1.00 78.67 ? 86 LEU A C 1 +ATOM 657 O O . LEU A 1 86 ? 33.061 -15.350 17.451 1.00 94.71 ? 86 LEU A O 1 +ATOM 658 C CB . LEU A 1 86 ? 30.169 -16.618 18.216 1.00 42.30 ? 86 LEU A CB 1 +ATOM 659 C CG . LEU A 1 86 ? 29.897 -15.145 18.261 1.00 41.74 ? 86 LEU A CG 1 +ATOM 660 C CD1 . LEU A 1 86 ? 29.797 -14.521 16.860 1.00 53.19 ? 86 LEU A CD1 1 +ATOM 661 C CD2 . LEU A 1 86 ? 28.626 -14.882 19.046 1.00 40.78 ? 86 LEU A CD2 1 +ATOM 662 N N . GLN A 1 87 ? 33.235 -16.813 19.161 1.00 85.84 ? 87 GLN A N 1 +ATOM 663 C CA . GLN A 1 87 ? 34.317 -16.071 19.795 1.00 89.48 ? 87 GLN A CA 1 +ATOM 664 C C . GLN A 1 87 ? 35.553 -15.918 18.868 1.00 94.52 ? 87 GLN A C 1 +ATOM 665 O O . GLN A 1 87 ? 36.141 -14.829 18.721 1.00 89.08 ? 87 GLN A O 1 +ATOM 666 C CB . GLN A 1 87 ? 34.685 -16.743 21.117 1.00 96.75 ? 87 GLN A CB 1 +ATOM 667 C CG . GLN A 1 87 ? 35.129 -15.757 22.194 1.00 117.30 ? 87 GLN A CG 1 +ATOM 668 C CD . GLN A 1 87 ? 34.258 -14.500 22.249 1.00 103.26 ? 87 GLN A CD 1 +ATOM 669 O OE1 . GLN A 1 87 ? 33.051 -14.581 22.472 1.00 119.69 ? 87 GLN A OE1 1 +ATOM 670 N NE2 . GLN A 1 87 ? 34.882 -13.332 22.101 1.00 109.73 ? 87 GLN A NE2 1 +ATOM 671 N N . ASN A 1 88 ? 35.911 -17.011 18.202 1.00 73.86 ? 88 ASN A N 1 +ATOM 672 C CA . ASN A 1 88 ? 37.006 -16.997 17.240 1.00 63.45 ? 88 ASN A CA 1 +ATOM 673 C C . ASN A 1 88 ? 36.728 -16.102 16.046 1.00 73.74 ? 88 ASN A C 1 +ATOM 674 O O . ASN A 1 88 ? 37.639 -15.466 15.489 1.00 65.18 ? 88 ASN A O 1 +ATOM 675 C CB . ASN A 1 88 ? 37.225 -18.400 16.721 1.00 66.09 ? 88 ASN A CB 1 +ATOM 676 C CG . ASN A 1 88 ? 37.437 -19.383 17.841 1.00 78.07 ? 88 ASN A CG 1 +ATOM 677 O OD1 . ASN A 1 88 ? 38.131 -19.069 18.802 1.00 74.51 ? 88 ASN A OD1 1 +ATOM 678 N ND2 . ASN A 1 88 ? 36.896 -20.596 17.695 1.00 77.57 ? 88 ASN A ND2 1 +ATOM 679 N N . LEU A 1 89 ? 35.470 -16.123 15.596 1.00 74.89 ? 89 LEU A N 1 +ATOM 680 C CA . LEU A 1 89 ? 35.043 -15.318 14.474 1.00 61.65 ? 89 LEU A CA 1 +ATOM 681 C C . LEU A 1 89 ? 35.288 -13.819 14.832 1.00 62.43 ? 89 LEU A C 1 +ATOM 682 O O . LEU A 1 89 ? 35.817 -13.032 14.025 1.00 61.41 ? 89 LEU A O 1 +ATOM 683 C CB . LEU A 1 89 ? 33.582 -15.606 14.190 1.00 61.14 ? 89 LEU A CB 1 +ATOM 684 C CG . LEU A 1 89 ? 33.054 -15.447 12.768 1.00 75.38 ? 89 LEU A CG 1 +ATOM 685 C CD1 . LEU A 1 89 ? 32.017 -14.322 12.687 1.00 69.15 ? 89 LEU A CD1 1 +ATOM 686 C CD2 . LEU A 1 89 ? 34.176 -15.202 11.769 1.00 72.89 ? 89 LEU A CD2 1 +ATOM 687 N N . LEU A 1 90 ? 34.964 -13.455 16.066 1.00 62.21 ? 90 LEU A N 1 +ATOM 688 C CA . LEU A 1 90 ? 35.078 -12.073 16.492 1.00 70.36 ? 90 LEU A CA 1 +ATOM 689 C C . LEU A 1 90 ? 36.544 -11.688 16.632 1.00 72.93 ? 90 LEU A C 1 +ATOM 690 O O . LEU A 1 90 ? 36.929 -10.513 16.445 1.00 52.80 ? 90 LEU A O 1 +ATOM 691 C CB . LEU A 1 90 ? 34.327 -11.870 17.811 1.00 64.47 ? 90 LEU A CB 1 +ATOM 692 C CG . LEU A 1 90 ? 32.828 -12.154 17.716 1.00 54.76 ? 90 LEU A CG 1 +ATOM 693 C CD1 . LEU A 1 90 ? 32.301 -12.352 19.112 1.00 63.89 ? 90 LEU A CD1 1 +ATOM 694 C CD2 . LEU A 1 90 ? 32.112 -10.998 17.012 1.00 54.68 ? 90 LEU A CD2 1 +ATOM 695 N N . ASN A 1 91 ? 37.352 -12.684 16.977 1.00 77.00 ? 91 ASN A N 1 +ATOM 696 C CA . ASN A 1 91 ? 38.771 -12.474 17.138 1.00 86.23 ? 91 ASN A CA 1 +ATOM 697 C C . ASN A 1 91 ? 39.441 -12.230 15.792 1.00 75.52 ? 91 ASN A C 1 +ATOM 698 O O . ASN A 1 91 ? 40.215 -11.256 15.647 1.00 74.88 ? 91 ASN A O 1 +ATOM 699 C CB . ASN A 1 91 ? 39.405 -13.677 17.830 1.00 108.17 ? 91 ASN A CB 1 +ATOM 700 C CG . ASN A 1 91 ? 40.219 -13.267 19.044 1.00 111.22 ? 91 ASN A CG 1 +ATOM 701 O OD1 . ASN A 1 91 ? 39.725 -12.485 19.855 1.00 99.96 ? 91 ASN A OD1 1 +ATOM 702 N ND2 . ASN A 1 91 ? 41.529 -13.584 19.037 1.00 119.89 ? 91 ASN A ND2 1 +ATOM 703 N N . GLU A 1 92 ? 39.164 -13.097 14.819 1.00 44.63 ? 92 GLU A N 1 +ATOM 704 C CA . GLU A 1 92 ? 39.676 -12.845 13.466 1.00 52.26 ? 92 GLU A CA 1 +ATOM 705 C C . GLU A 1 92 ? 39.262 -11.464 12.891 1.00 56.33 ? 92 GLU A C 1 +ATOM 706 O O . GLU A 1 92 ? 40.039 -10.783 12.204 1.00 42.97 ? 92 GLU A O 1 +ATOM 707 C CB . GLU A 1 92 ? 39.227 -13.917 12.496 1.00 56.75 ? 92 GLU A CB 1 +ATOM 708 C CG . GLU A 1 92 ? 40.172 -15.089 12.392 1.00 63.64 ? 92 GLU A CG 1 +ATOM 709 C CD . GLU A 1 92 ? 41.623 -14.684 12.070 1.00 82.54 ? 92 GLU A CD 1 +ATOM 710 O OE1 . GLU A 1 92 ? 41.887 -14.046 11.014 1.00 94.11 ? 92 GLU A OE1 1 +ATOM 711 O OE2 . GLU A 1 92 ? 42.520 -15.081 12.836 1.00 76.05 ? 92 GLU A OE2 1 +ATOM 712 N N . ARG A 1 93 ? 38.053 -11.037 13.231 1.00 62.42 ? 93 ARG A N 1 +ATOM 713 C CA . ARG A 1 93 ? 37.587 -9.720 12.838 1.00 66.25 ? 93 ARG A CA 1 +ATOM 714 C C . ARG A 1 93 ? 38.339 -8.577 13.590 1.00 71.66 ? 93 ARG A C 1 +ATOM 715 O O . ARG A 1 93 ? 38.637 -7.539 12.994 1.00 67.24 ? 93 ARG A O 1 +ATOM 716 C CB . ARG A 1 93 ? 36.070 -9.629 13.018 1.00 59.29 ? 93 ARG A CB 1 +ATOM 717 C CG . ARG A 1 93 ? 35.357 -10.506 12.043 1.00 47.19 ? 93 ARG A CG 1 +ATOM 718 C CD . ARG A 1 93 ? 33.908 -10.742 12.393 1.00 57.11 ? 93 ARG A CD 1 +ATOM 719 N NE . ARG A 1 93 ? 33.021 -9.916 11.590 1.00 66.49 ? 93 ARG A NE 1 +ATOM 720 C CZ . ARG A 1 93 ? 32.562 -8.727 11.944 1.00 61.52 ? 93 ARG A CZ 1 +ATOM 721 N NH1 . ARG A 1 93 ? 32.890 -8.176 13.123 1.00 43.15 ? 93 ARG A NH1 1 +ATOM 722 N NH2 . ARG A 1 93 ? 31.690 -8.129 11.124 1.00 69.29 ? 93 ARG A NH2 1 +ATOM 723 N N . LYS A 1 94 ? 38.707 -8.793 14.847 1.00 66.42 ? 94 LYS A N 1 +ATOM 724 C CA . LYS A 1 94 ? 39.600 -7.865 15.517 1.00 77.31 ? 94 LYS A CA 1 +ATOM 725 C C . LYS A 1 94 ? 40.928 -7.746 14.758 1.00 80.85 ? 94 LYS A C 1 +ATOM 726 O O . LYS A 1 94 ? 41.501 -6.643 14.646 1.00 67.79 ? 94 LYS A O 1 +ATOM 727 C CB . LYS A 1 94 ? 39.880 -8.318 16.949 1.00 94.08 ? 94 LYS A CB 1 +ATOM 728 C CG . LYS A 1 94 ? 38.860 -7.852 17.968 1.00 134.92 ? 94 LYS A CG 1 +ATOM 729 C CD . LYS A 1 94 ? 39.117 -8.519 19.313 1.00 166.24 ? 94 LYS A CD 1 +ATOM 730 C CE . LYS A 1 94 ? 38.472 -7.778 20.483 1.00 177.46 ? 94 LYS A CE 1 +ATOM 731 N NZ . LYS A 1 94 ? 38.454 -8.640 21.697 1.00 179.41 ? 94 LYS A NZ 1 +ATOM 732 N N . ILE A 1 95 ? 41.466 -8.890 14.316 1.00 72.24 ? 95 ILE A N 1 +ATOM 733 C CA . ILE A 1 95 ? 42.801 -8.908 13.711 1.00 69.68 ? 95 ILE A CA 1 +ATOM 734 C C . ILE A 1 95 ? 42.800 -8.255 12.354 1.00 53.93 ? 95 ILE A C 1 +ATOM 735 O O . ILE A 1 95 ? 43.745 -7.505 12.004 1.00 40.73 ? 95 ILE A O 1 +ATOM 736 C CB . ILE A 1 95 ? 43.382 -10.315 13.547 1.00 78.57 ? 95 ILE A CB 1 +ATOM 737 C CG1 . ILE A 1 95 ? 43.262 -11.116 14.847 1.00 66.81 ? 95 ILE A CG1 1 +ATOM 738 C CG2 . ILE A 1 95 ? 44.859 -10.182 13.187 1.00 116.15 ? 95 ILE A CG2 1 +ATOM 739 C CD1 . ILE A 1 95 ? 44.097 -12.381 14.894 1.00 69.29 ? 95 ILE A CD1 1 +ATOM 740 N N . ILE A 1 96 ? 41.724 -8.538 11.618 1.00 51.59 ? 96 ILE A N 1 +ATOM 741 C CA . ILE A 1 96 ? 41.424 -7.818 10.387 1.00 52.69 ? 96 ILE A CA 1 +ATOM 742 C C . ILE A 1 96 ? 41.423 -6.305 10.634 1.00 52.86 ? 96 ILE A C 1 +ATOM 743 O O . ILE A 1 96 ? 42.199 -5.581 10.002 1.00 78.12 ? 96 ILE A O 1 +ATOM 744 C CB . ILE A 1 96 ? 40.090 -8.235 9.734 1.00 36.18 ? 96 ILE A CB 1 +ATOM 745 C CG1 . ILE A 1 96 ? 40.149 -9.677 9.296 1.00 31.71 ? 96 ILE A CG1 1 +ATOM 746 C CG2 . ILE A 1 96 ? 39.815 -7.375 8.517 1.00 28.76 ? 96 ILE A CG2 1 +ATOM 747 C CD1 . ILE A 1 96 ? 38.897 -10.124 8.602 1.00 33.37 ? 96 ILE A CD1 1 +ATOM 748 N N . ARG A 1 97 ? 40.575 -5.842 11.535 1.00 51.20 ? 97 ARG A N 1 +ATOM 749 C CA . ARG A 1 97 ? 40.387 -4.405 11.722 1.00 78.01 ? 97 ARG A CA 1 +ATOM 750 C C . ARG A 1 97 ? 41.679 -3.759 12.187 1.00 74.32 ? 97 ARG A C 1 +ATOM 751 O O . ARG A 1 97 ? 41.946 -2.586 11.896 1.00 59.36 ? 97 ARG A O 1 +ATOM 752 C CB . ARG A 1 97 ? 39.270 -4.118 12.730 1.00 105.54 ? 97 ARG A CB 1 +ATOM 753 C CG . ARG A 1 97 ? 37.954 -3.644 12.116 1.00 107.90 ? 97 ARG A CG 1 +ATOM 754 C CD . ARG A 1 97 ? 36.931 -3.325 13.203 1.00 128.86 ? 97 ARG A CD 1 +ATOM 755 N NE . ARG A 1 97 ? 36.255 -4.519 13.714 1.00 121.60 ? 97 ARG A NE 1 +ATOM 756 C CZ . ARG A 1 97 ? 35.057 -4.942 13.313 1.00 136.28 ? 97 ARG A CZ 1 +ATOM 757 N NH1 . ARG A 1 97 ? 34.370 -4.270 12.378 1.00 128.85 ? 97 ARG A NH1 1 +ATOM 758 N NH2 . ARG A 1 97 ? 34.547 -6.061 13.834 1.00 117.96 ? 97 ARG A NH2 1 +ATOM 759 N N . ALA A 1 98 ? 42.498 -4.531 12.894 1.00 76.46 ? 98 ALA A N 1 +ATOM 760 C CA . ALA A 1 98 ? 43.789 -4.020 13.364 1.00 96.53 ? 98 ALA A CA 1 +ATOM 761 C C . ALA A 1 98 ? 44.816 -3.976 12.241 1.00 72.71 ? 98 ALA A C 1 +ATOM 762 O O . ALA A 1 98 ? 45.690 -3.105 12.216 1.00 46.97 ? 98 ALA A O 1 +ATOM 763 C CB . ALA A 1 98 ? 44.300 -4.881 14.492 1.00 114.64 ? 98 ALA A CB 1 +ATOM 764 N N . ALA A 1 99 ? 44.618 -4.855 11.262 1.00 81.44 ? 99 ALA A N 1 +ATOM 765 C CA . ALA A 1 99 ? 45.472 -4.893 10.075 1.00 87.28 ? 99 ALA A CA 1 +ATOM 766 C C . ALA A 1 99 ? 45.298 -3.656 9.186 1.00 81.33 ? 99 ALA A C 1 +ATOM 767 O O . ALA A 1 99 ? 46.275 -3.038 8.764 1.00 103.86 ? 99 ALA A O 1 +ATOM 768 C CB . ALA A 1 99 ? 45.213 -6.165 9.270 1.00 90.60 ? 99 ALA A CB 1 +ATOM 769 N N . GLN A 1 100 ? 44.057 -3.338 8.858 1.00 70.23 ? 100 GLN A N 1 +ATOM 770 C CA . GLN A 1 100 ? 43.782 -2.464 7.728 1.00 86.63 ? 100 GLN A CA 1 +ATOM 771 C C . GLN A 1 100 ? 43.313 -1.092 8.138 1.00 83.26 ? 100 GLN A C 1 +ATOM 772 O O . GLN A 1 100 ? 42.907 -0.284 7.285 1.00 117.29 ? 100 GLN A O 1 +ATOM 773 C CB . GLN A 1 100 ? 42.774 -3.113 6.745 1.00 95.90 ? 100 GLN A CB 1 +ATOM 774 C CG . GLN A 1 100 ? 41.607 -3.827 7.390 1.00 74.81 ? 100 GLN A CG 1 +ATOM 775 C CD . GLN A 1 100 ? 41.049 -4.948 6.535 1.00 64.22 ? 100 GLN A CD 1 +ATOM 776 O OE1 . GLN A 1 100 ? 41.739 -5.929 6.177 1.00 39.22 ? 100 GLN A OE1 1 +ATOM 777 N NE2 . GLN A 1 100 ? 39.773 -4.802 6.194 1.00 65.21 ? 100 GLN A NE2 1 +ATOM 778 N N . GLU A 1 101 ? 43.353 -0.821 9.429 1.00 87.72 ? 101 GLU A N 1 +ATOM 779 C CA . GLU A 1 101 ? 42.849 0.458 9.934 1.00 118.01 ? 101 GLU A CA 1 +ATOM 780 C C . GLU A 1 101 ? 43.706 1.634 9.478 1.00 118.21 ? 101 GLU A C 1 +ATOM 781 O O . GLU A 1 101 ? 43.235 2.782 9.445 1.00 101.44 ? 101 GLU A O 1 +ATOM 782 C CB . GLU A 1 101 ? 42.729 0.431 11.463 1.00 124.69 ? 101 GLU A CB 1 +ATOM 783 C CG . GLU A 1 101 ? 43.983 -0.035 12.190 1.00 115.45 ? 101 GLU A CG 1 +ATOM 784 C CD . GLU A 1 101 ? 43.838 0.039 13.701 1.00 103.19 ? 101 GLU A CD 1 +ATOM 785 O OE1 . GLU A 1 101 ? 42.692 0.118 14.184 1.00 107.28 ? 101 GLU A OE1 1 +ATOM 786 O OE2 . GLU A 1 101 ? 44.865 0.001 14.412 1.00 104.76 ? 101 GLU A OE2 1 +ATOM 787 N N . ASN A 1 102 ? 44.964 1.362 9.146 1.00 112.41 ? 102 ASN A N 1 +ATOM 788 C CA . ASN A 1 102 ? 45.875 2.433 8.771 1.00 123.02 ? 102 ASN A CA 1 +ATOM 789 C C . ASN A 1 102 ? 45.913 2.705 7.277 1.00 132.73 ? 102 ASN A C 1 +ATOM 790 O O . ASN A 1 102 ? 46.628 3.598 6.827 1.00 148.33 ? 102 ASN A O 1 +ATOM 791 C CB . ASN A 1 102 ? 47.271 2.124 9.286 1.00 117.65 ? 102 ASN A CB 1 +ATOM 792 C CG . ASN A 1 102 ? 47.360 2.260 10.788 1.00 110.79 ? 102 ASN A CG 1 +ATOM 793 O OD1 . ASN A 1 102 ? 47.488 3.374 11.320 1.00 111.67 ? 102 ASN A OD1 1 +ATOM 794 N ND2 . ASN A 1 102 ? 47.274 1.131 11.485 1.00 100.12 ? 102 ASN A ND2 1 +ATOM 795 N N . GLY A 1 103 ? 45.176 1.920 6.504 1.00 140.08 ? 103 GLY A N 1 +ATOM 796 C CA . GLY A 1 103 ? 45.179 2.070 5.049 1.00 145.59 ? 103 GLY A CA 1 +ATOM 797 C C . GLY A 1 103 ? 46.537 1.889 4.386 1.00 134.72 ? 103 GLY A C 1 +ATOM 798 O O . GLY A 1 103 ? 46.867 2.564 3.407 1.00 186.02 ? 103 GLY A O 1 +ATOM 799 N N . THR A 1 104 ? 47.355 1.015 4.948 1.00 108.26 ? 104 THR A N 1 +ATOM 800 C CA . THR A 1 104 ? 48.574 0.623 4.286 1.00 106.71 ? 104 THR A CA 1 +ATOM 801 C C . THR A 1 104 ? 48.339 -0.696 3.600 1.00 100.54 ? 104 THR A C 1 +ATOM 802 O O . THR A 1 104 ? 49.015 -1.002 2.636 1.00 101.04 ? 104 THR A O 1 +ATOM 803 C CB . THR A 1 104 ? 49.784 0.548 5.259 1.00 133.48 ? 104 THR A CB 1 +ATOM 804 O OG1 . THR A 1 104 ? 49.591 -0.463 6.263 1.00 107.57 ? 104 THR A OG1 1 +ATOM 805 C CG2 . THR A 1 104 ? 50.002 1.907 5.942 1.00 143.87 ? 104 THR A CG2 1 +ATOM 806 N N . VAL A 1 105 ? 47.408 -1.502 4.116 1.00 104.33 ? 105 VAL A N 1 +ATOM 807 C CA . VAL A 1 105 ? 47.299 -2.912 3.682 1.00 120.79 ? 105 VAL A CA 1 +ATOM 808 C C . VAL A 1 105 ? 46.973 -2.937 2.189 1.00 145.04 ? 105 VAL A C 1 +ATOM 809 O O . VAL A 1 105 ? 46.211 -2.095 1.690 1.00 123.23 ? 105 VAL A O 1 +ATOM 810 C CB . VAL A 1 105 ? 46.283 -3.767 4.524 1.00 91.58 ? 105 VAL A CB 1 +ATOM 811 C CG1 . VAL A 1 105 ? 45.541 -4.772 3.653 1.00 94.03 ? 105 VAL A CG1 1 +ATOM 812 C CG2 . VAL A 1 105 ? 46.984 -4.501 5.683 1.00 66.23 ? 105 VAL A CG2 1 +ATOM 813 N N . ALA A 1 106 ? 47.595 -3.896 1.495 1.00 153.18 ? 106 ALA A N 1 +ATOM 814 C CA . ALA A 1 106 ? 47.558 -3.988 0.039 1.00 136.13 ? 106 ALA A CA 1 +ATOM 815 C C . ALA A 1 106 ? 46.139 -4.212 -0.457 1.00 142.11 ? 106 ALA A C 1 +ATOM 816 O O . ALA A 1 106 ? 45.407 -5.038 0.093 1.00 187.65 ? 106 ALA A O 1 +ATOM 817 C CB . ALA A 1 106 ? 48.465 -5.116 -0.429 1.00 140.97 ? 106 ALA A CB 1 +ATOM 818 N N . ILE A 1 107 ? 45.750 -3.451 -1.478 1.00 143.11 ? 107 ILE A N 1 +ATOM 819 C CA . ILE A 1 107 ? 44.366 -3.436 -1.971 1.00 143.22 ? 107 ILE A CA 1 +ATOM 820 C C . ILE A 1 107 ? 43.876 -4.833 -2.414 1.00 143.41 ? 107 ILE A C 1 +ATOM 821 O O . ILE A 1 107 ? 42.692 -5.155 -2.302 1.00 115.91 ? 107 ILE A O 1 +ATOM 822 C CB . ILE A 1 107 ? 44.208 -2.413 -3.129 1.00 138.74 ? 107 ILE A CB 1 +ATOM 823 C CG1 . ILE A 1 107 ? 42.728 -2.163 -3.452 1.00 120.24 ? 107 ILE A CG1 1 +ATOM 824 C CG2 . ILE A 1 107 ? 44.960 -2.881 -4.370 1.00 141.71 ? 107 ILE A CG2 1 +ATOM 825 C CD1 . ILE A 1 107 ? 41.906 -1.671 -2.278 1.00 121.34 ? 107 ILE A CD1 1 +ATOM 826 N N . ASN A 1 108 ? 44.798 -5.662 -2.896 1.00 157.05 ? 108 ASN A N 1 +ATOM 827 C CA . ASN A 1 108 ? 44.492 -7.056 -3.253 1.00 158.34 ? 108 ASN A CA 1 +ATOM 828 C C . ASN A 1 108 ? 44.229 -7.901 -2.012 1.00 148.50 ? 108 ASN A C 1 +ATOM 829 O O . ASN A 1 108 ? 43.411 -8.817 -2.029 1.00 131.23 ? 108 ASN A O 1 +ATOM 830 C CB . ASN A 1 108 ? 45.657 -7.678 -4.029 1.00 168.73 ? 108 ASN A CB 1 +ATOM 831 C CG . ASN A 1 108 ? 46.423 -6.655 -4.847 1.00 205.34 ? 108 ASN A CG 1 +ATOM 832 O OD1 . ASN A 1 108 ? 46.069 -6.369 -5.990 1.00 223.88 ? 108 ASN A OD1 1 +ATOM 833 N ND2 . ASN A 1 108 ? 47.486 -6.100 -4.263 1.00 226.81 ? 108 ASN A ND2 1 +ATOM 834 N N . ASN A 1 109 ? 44.959 -7.591 -0.947 1.00 135.18 ? 109 ASN A N 1 +ATOM 835 C CA . ASN A 1 109 ? 44.926 -8.362 0.287 1.00 115.71 ? 109 ASN A CA 1 +ATOM 836 C C . ASN A 1 109 ? 43.823 -7.923 1.251 1.00 104.78 ? 109 ASN A C 1 +ATOM 837 O O . ASN A 1 109 ? 43.442 -8.685 2.147 1.00 131.86 ? 109 ASN A O 1 +ATOM 838 C CB . ASN A 1 109 ? 46.271 -8.258 0.994 1.00 111.26 ? 109 ASN A CB 1 +ATOM 839 C CG . ASN A 1 109 ? 46.972 -9.594 1.095 1.00 133.37 ? 109 ASN A CG 1 +ATOM 840 O OD1 . ASN A 1 109 ? 47.171 -10.123 2.189 1.00 124.99 ? 109 ASN A OD1 1 +ATOM 841 N ND2 . ASN A 1 109 ? 47.333 -10.163 -0.056 1.00 146.45 ? 109 ASN A ND2 1 +ATOM 842 N N . ARG A 1 110 ? 43.283 -6.729 1.015 1.00 83.00 ? 110 ARG A N 1 +ATOM 843 C CA . ARG A 1 110 ? 42.278 -6.119 1.876 1.00 72.87 ? 110 ARG A CA 1 +ATOM 844 C C . ARG A 1 110 ? 41.063 -7.039 2.065 1.00 87.85 ? 110 ARG A C 1 +ATOM 845 O O . ARG A 1 110 ? 40.526 -7.593 1.099 1.00 86.07 ? 110 ARG A O 1 +ATOM 846 C CB . ARG A 1 110 ? 41.808 -4.791 1.248 1.00 84.19 ? 110 ARG A CB 1 +ATOM 847 C CG . ARG A 1 110 ? 41.247 -3.779 2.229 1.00 101.83 ? 110 ARG A CG 1 +ATOM 848 C CD . ARG A 1 110 ? 41.584 -2.345 1.840 1.00 114.45 ? 110 ARG A CD 1 +ATOM 849 N NE . ARG A 1 110 ? 40.577 -1.744 0.959 1.00 130.14 ? 110 ARG A NE 1 +ATOM 850 C CZ . ARG A 1 110 ? 39.872 -0.634 1.234 1.00 131.13 ? 110 ARG A CZ 1 +ATOM 851 N NH1 . ARG A 1 110 ? 40.039 0.029 2.381 1.00 108.44 ? 110 ARG A NH1 1 +ATOM 852 N NH2 . ARG A 1 110 ? 38.998 -0.175 0.343 1.00 119.09 ? 110 ARG A NH2 1 +ATOM 853 N N . ILE A 1 111 ? 40.598 -7.174 3.307 1.00 106.17 ? 111 ILE A N 1 +ATOM 854 C CA . ILE A 1 111 ? 39.338 -7.910 3.596 1.00 88.75 ? 111 ILE A CA 1 +ATOM 855 C C . ILE A 1 111 ? 38.240 -6.943 4.009 1.00 87.46 ? 111 ILE A C 1 +ATOM 856 O O . ILE A 1 111 ? 38.384 -6.287 5.026 1.00 83.88 ? 111 ILE A O 1 +ATOM 857 C CB . ILE A 1 111 ? 39.507 -8.944 4.726 1.00 75.69 ? 111 ILE A CB 1 +ATOM 858 C CG1 . ILE A 1 111 ? 40.512 -9.996 4.266 1.00 110.63 ? 111 ILE A CG1 1 +ATOM 859 C CG2 . ILE A 1 111 ? 38.182 -9.582 5.058 1.00 55.20 ? 111 ILE A CG2 1 +ATOM 860 C CD1 . ILE A 1 111 ? 41.002 -10.914 5.364 1.00 115.12 ? 111 ILE A CD1 1 +ATOM 861 N N . PRO A 1 112 ? 37.159 -6.837 3.210 1.00 90.77 ? 112 PRO A N 1 +ATOM 862 C CA . PRO A 1 112 ? 36.101 -5.876 3.491 1.00 79.85 ? 112 PRO A CA 1 +ATOM 863 C C . PRO A 1 112 ? 35.144 -6.429 4.529 1.00 87.94 ? 112 PRO A C 1 +ATOM 864 O O . PRO A 1 112 ? 34.744 -7.605 4.444 1.00 80.99 ? 112 PRO A O 1 +ATOM 865 C CB . PRO A 1 112 ? 35.396 -5.743 2.160 1.00 89.43 ? 112 PRO A CB 1 +ATOM 866 C CG . PRO A 1 112 ? 35.565 -7.087 1.513 1.00 103.32 ? 112 PRO A CG 1 +ATOM 867 C CD . PRO A 1 112 ? 36.848 -7.675 2.034 1.00 105.56 ? 112 PRO A CD 1 +ATOM 868 N N . LEU A 1 113 ? 34.916 -5.640 5.580 1.00 107.26 ? 113 LEU A N 1 +ATOM 869 C CA . LEU A 1 113 ? 34.205 -6.113 6.773 1.00 88.64 ? 113 LEU A CA 1 +ATOM 870 C C . LEU A 1 113 ? 32.847 -5.506 6.847 1.00 97.91 ? 113 LEU A C 1 +ATOM 871 O O . LEU A 1 113 ? 32.635 -4.296 6.598 1.00 93.77 ? 113 LEU A O 1 +ATOM 872 C CB . LEU A 1 113 ? 34.947 -5.805 8.068 1.00 73.18 ? 113 LEU A CB 1 +ATOM 873 C CG . LEU A 1 113 ? 35.956 -6.852 8.499 1.00 75.68 ? 113 LEU A CG 1 +ATOM 874 C CD1 . LEU A 1 113 ? 36.531 -6.423 9.826 1.00 95.02 ? 113 LEU A CD1 1 +ATOM 875 C CD2 . LEU A 1 113 ? 35.392 -8.247 8.594 1.00 64.93 ? 113 LEU A CD2 1 +ATOM 876 N N . GLN A 1 114 ? 31.928 -6.375 7.217 1.00 93.71 ? 114 GLN A N 1 +ATOM 877 C CA . GLN A 1 114 ? 30.523 -6.095 7.098 1.00 95.65 ? 114 GLN A CA 1 +ATOM 878 C C . GLN A 1 114 ? 29.937 -6.698 8.343 1.00 80.89 ? 114 GLN A C 1 +ATOM 879 O O . GLN A 1 114 ? 30.506 -7.632 8.895 1.00 66.33 ? 114 GLN A O 1 +ATOM 880 C CB . GLN A 1 114 ? 29.936 -6.753 5.838 1.00 84.01 ? 114 GLN A CB 1 +ATOM 881 C CG . GLN A 1 114 ? 28.793 -5.966 5.188 1.00 76.21 ? 114 GLN A CG 1 +ATOM 882 C CD . GLN A 1 114 ? 27.938 -6.779 4.196 1.00 78.04 ? 114 GLN A CD 1 +ATOM 883 O OE1 . GLN A 1 114 ? 26.781 -6.410 3.821 1.00 61.50 ? 114 GLN A OE1 1 +ATOM 884 N NE2 . GLN A 1 114 ? 28.484 -7.919 3.792 1.00 71.34 ? 114 GLN A NE2 1 +ATOM 885 N N . SER A 1 115 ? 28.861 -6.086 8.828 1.00 76.35 ? 115 SER A N 1 +ATOM 886 C CA . SER A 1 115 ? 28.297 -6.429 10.126 1.00 68.97 ? 115 SER A CA 1 +ATOM 887 C C . SER A 1 115 ? 27.880 -7.861 10.075 1.00 70.29 ? 115 SER A C 1 +ATOM 888 O O . SER A 1 115 ? 27.696 -8.418 8.956 1.00 79.26 ? 115 SER A O 1 +ATOM 889 C CB . SER A 1 115 ? 27.090 -5.551 10.432 1.00 68.99 ? 115 SER A CB 1 +ATOM 890 O OG . SER A 1 115 ? 26.179 -5.520 9.327 1.00 67.29 ? 115 SER A OG 1 +ATOM 891 N N . LEU A 1 116 ? 27.816 -8.507 11.237 1.00 64.45 ? 116 LEU A N 1 +ATOM 892 C CA . LEU A 1 116 ? 27.692 -9.950 11.198 1.00 76.74 ? 116 LEU A CA 1 +ATOM 893 C C . LEU A 1 116 ? 26.257 -10.260 10.777 1.00 84.30 ? 116 LEU A C 1 +ATOM 894 O O . LEU A 1 116 ? 25.350 -9.661 11.336 1.00 66.66 ? 116 LEU A O 1 +ATOM 895 C CB . LEU A 1 116 ? 27.994 -10.572 12.539 1.00 66.31 ? 116 LEU A CB 1 +ATOM 896 C CG . LEU A 1 116 ? 29.435 -10.506 13.036 1.00 59.15 ? 116 LEU A CG 1 +ATOM 897 C CD1 . LEU A 1 116 ? 29.612 -9.290 13.947 1.00 68.78 ? 116 LEU A CD1 1 +ATOM 898 C CD2 . LEU A 1 116 ? 29.770 -11.803 13.778 1.00 52.11 ? 116 LEU A CD2 1 +ATOM 899 N N . THR A 1 117 ? 26.081 -11.074 9.720 1.00 73.91 ? 117 THR A N 1 +ATOM 900 C CA . THR A 1 117 ? 24.757 -11.396 9.175 1.00 62.57 ? 117 THR A CA 1 +ATOM 901 C C . THR A 1 117 ? 23.967 -11.986 10.281 1.00 61.49 ? 117 THR A C 1 +ATOM 902 O O . THR A 1 117 ? 24.487 -12.823 11.041 1.00 43.67 ? 117 THR A O 1 +ATOM 903 C CB . THR A 1 117 ? 24.818 -12.455 8.072 1.00 67.48 ? 117 THR A CB 1 +ATOM 904 O OG1 . THR A 1 117 ? 25.703 -12.008 7.045 1.00 121.00 ? 117 THR A OG1 1 +ATOM 905 C CG2 . THR A 1 117 ? 23.455 -12.682 7.479 1.00 73.02 ? 117 THR A CG2 1 +ATOM 906 N N . ALA A 1 118 ? 22.741 -11.485 10.444 1.00 73.81 ? 118 ALA A N 1 +ATOM 907 C CA . ALA A 1 118 ? 21.939 -11.787 11.645 1.00 85.73 ? 118 ALA A CA 1 +ATOM 908 C C . ALA A 1 118 ? 20.713 -12.599 11.346 1.00 59.39 ? 118 ALA A C 1 +ATOM 909 O O . ALA A 1 118 ? 20.022 -12.332 10.352 1.00 42.36 ? 118 ALA A O 1 +ATOM 910 C CB . ALA A 1 118 ? 21.517 -10.510 12.347 1.00 116.34 ? 118 ALA A CB 1 +ATOM 911 N N . ALA A 1 119 ? 20.441 -13.548 12.247 1.00 44.90 ? 119 ALA A N 1 +ATOM 912 C CA . ALA A 1 119 ? 19.392 -14.542 12.041 1.00 60.61 ? 119 ALA A CA 1 +ATOM 913 C C . ALA A 1 119 ? 18.033 -14.046 12.510 1.00 80.45 ? 119 ALA A C 1 +ATOM 914 O O . ALA A 1 119 ? 17.960 -13.155 13.378 1.00 57.13 ? 119 ALA A O 1 +ATOM 915 C CB . ALA A 1 119 ? 19.733 -15.810 12.771 1.00 57.86 ? 119 ALA A CB 1 +ATOM 916 N N . ASN A 1 120 ? 16.954 -14.598 11.928 1.00 89.20 ? 120 ASN A N 1 +ATOM 917 C CA . ASN A 1 120 ? 15.599 -14.248 12.387 1.00 98.07 ? 120 ASN A CA 1 +ATOM 918 C C . ASN A 1 120 ? 15.041 -15.281 13.351 1.00 73.65 ? 120 ASN A C 1 +ATOM 919 O O . ASN A 1 120 ? 14.448 -14.950 14.374 1.00 60.25 ? 120 ASN A O 1 +ATOM 920 C CB . ASN A 1 120 ? 14.619 -14.065 11.218 1.00 104.76 ? 120 ASN A CB 1 +ATOM 921 C CG . ASN A 1 120 ? 13.203 -13.704 11.685 1.00 116.92 ? 120 ASN A CG 1 +ATOM 922 O OD1 . ASN A 1 120 ? 13.014 -12.985 12.689 1.00 115.30 ? 120 ASN A OD1 1 +ATOM 923 N ND2 . ASN A 1 120 ? 12.198 -14.238 10.978 1.00 102.17 ? 120 ASN A ND2 1 +ATOM 924 N N . ILE A 1 121 ? 15.187 -16.541 12.991 1.00 60.82 ? 121 ILE A N 1 +ATOM 925 C CA . ILE A 1 121 ? 14.777 -17.612 13.882 1.00 53.87 ? 121 ILE A CA 1 +ATOM 926 C C . ILE A 1 121 ? 16.042 -18.285 14.292 1.00 51.07 ? 121 ILE A C 1 +ATOM 927 O O . ILE A 1 121 ? 16.968 -18.447 13.503 1.00 51.66 ? 121 ILE A O 1 +ATOM 928 C CB . ILE A 1 121 ? 13.771 -18.612 13.222 1.00 55.75 ? 121 ILE A CB 1 +ATOM 929 C CG1 . ILE A 1 121 ? 14.435 -19.508 12.169 1.00 45.35 ? 121 ILE A CG1 1 +ATOM 930 C CG2 . ILE A 1 121 ? 12.578 -17.857 12.600 1.00 66.23 ? 121 ILE A CG2 1 +ATOM 931 C CD1 . ILE A 1 121 ? 14.551 -20.924 12.597 1.00 40.94 ? 121 ILE A CD1 1 +ATOM 932 N N . MET A 1 122 ? 16.123 -18.619 15.548 1.00 52.45 ? 122 MET A N 1 +ATOM 933 C CA . MET A 1 122 ? 17.141 -19.547 15.947 1.00 73.00 ? 122 MET A CA 1 +ATOM 934 C C . MET A 1 122 ? 16.520 -20.841 16.517 1.00 68.42 ? 122 MET A C 1 +ATOM 935 O O . MET A 1 122 ? 15.441 -20.827 17.079 1.00 120.02 ? 122 MET A O 1 +ATOM 936 C CB . MET A 1 122 ? 18.094 -18.873 16.928 1.00 86.58 ? 122 MET A CB 1 +ATOM 937 C CG . MET A 1 122 ? 17.451 -18.334 18.188 1.00 143.06 ? 122 MET A CG 1 +ATOM 938 S SD . MET A 1 122 ? 18.680 -18.256 19.531 1.00 133.88 ? 122 MET A SD 1 +ATOM 939 C CE . MET A 1 122 ? 17.643 -18.893 20.880 1.00 172.99 ? 122 MET A CE 1 +ATOM 940 N N . VAL A 1 123 ? 17.153 -21.973 16.240 1.00 58.91 ? 123 VAL A N 1 +ATOM 941 C CA . VAL A 1 123 ? 16.637 -23.279 16.645 1.00 46.26 ? 123 VAL A CA 1 +ATOM 942 C C . VAL A 1 123 ? 17.595 -23.913 17.588 1.00 46.36 ? 123 VAL A C 1 +ATOM 943 O O . VAL A 1 123 ? 18.777 -24.085 17.267 1.00 49.81 ? 123 VAL A O 1 +ATOM 944 C CB . VAL A 1 123 ? 16.402 -24.266 15.445 1.00 34.59 ? 123 VAL A CB 1 +ATOM 945 C CG1 . VAL A 1 123 ? 17.487 -24.157 14.416 1.00 30.38 ? 123 VAL A CG1 1 +ATOM 946 C CG2 . VAL A 1 123 ? 16.229 -25.693 15.929 1.00 27.63 ? 123 VAL A CG2 1 +ATOM 947 N N . GLU A 1 124 ? 17.094 -24.262 18.757 1.00 49.88 ? 124 GLU A N 1 +ATOM 948 C CA . GLU A 1 124 ? 17.890 -25.038 19.684 1.00 70.77 ? 124 GLU A CA 1 +ATOM 949 C C . GLU A 1 124 ? 17.181 -26.295 20.102 1.00 64.73 ? 124 GLU A C 1 +ATOM 950 O O . GLU A 1 124 ? 15.998 -26.446 19.856 1.00 106.06 ? 124 GLU A O 1 +ATOM 951 C CB . GLU A 1 124 ? 18.278 -24.201 20.908 1.00 77.78 ? 124 GLU A CB 1 +ATOM 952 C CG . GLU A 1 124 ? 17.301 -23.116 21.286 1.00 59.24 ? 124 GLU A CG 1 +ATOM 953 C CD . GLU A 1 124 ? 17.951 -22.094 22.189 1.00 71.10 ? 124 GLU A CD 1 +ATOM 954 O OE1 . GLU A 1 124 ? 19.158 -21.798 22.026 1.00 56.09 ? 124 GLU A OE1 1 +ATOM 955 O OE2 . GLU A 1 124 ? 17.265 -21.630 23.123 1.00 107.21 ? 124 GLU A OE2 1 +ATOM 956 N N . GLY A 1 125 ? 17.921 -27.187 20.754 1.00 63.38 ? 125 GLY A N 1 +ATOM 957 C CA . GLY A 1 125 ? 17.363 -28.429 21.196 1.00 72.13 ? 125 GLY A CA 1 +ATOM 958 C C . GLY A 1 125 ? 18.330 -29.190 22.071 1.00 71.38 ? 125 GLY A C 1 +ATOM 959 O O . GLY A 1 125 ? 19.170 -28.593 22.756 1.00 74.23 ? 125 GLY A O 1 +ATOM 960 N N . SER A 1 126 ? 18.101 -30.494 22.194 1.00 58.25 ? 126 SER A N 1 +ATOM 961 C CA . SER A 1 126 ? 18.774 -31.266 23.230 1.00 66.66 ? 126 SER A CA 1 +ATOM 962 C C . SER A 1 126 ? 18.649 -32.701 22.891 1.00 63.44 ? 126 SER A C 1 +ATOM 963 O O . SER A 1 126 ? 17.628 -33.121 22.361 1.00 77.80 ? 126 SER A O 1 +ATOM 964 C CB . SER A 1 126 ? 18.196 -31.045 24.660 1.00 77.05 ? 126 SER A CB 1 +ATOM 965 O OG . SER A 1 126 ? 17.649 -29.735 24.877 1.00 82.88 ? 126 SER A OG 1 +ATOM 966 N N . ILE A 1 127 ? 19.673 -33.471 23.217 1.00 70.11 ? 127 ILE A N 1 +ATOM 967 C CA . ILE A 1 127 ? 19.518 -34.916 23.194 1.00 83.26 ? 127 ILE A CA 1 +ATOM 968 C C . ILE A 1 127 ? 18.799 -35.297 24.484 1.00 80.69 ? 127 ILE A C 1 +ATOM 969 O O . ILE A 1 127 ? 19.422 -35.321 25.530 1.00 124.46 ? 127 ILE A O 1 +ATOM 970 C CB . ILE A 1 127 ? 20.873 -35.669 23.038 1.00 79.38 ? 127 ILE A CB 1 +ATOM 971 C CG1 . ILE A 1 127 ? 21.506 -35.372 21.668 1.00 90.99 ? 127 ILE A CG1 1 +ATOM 972 C CG2 . ILE A 1 127 ? 20.672 -37.177 23.207 1.00 62.04 ? 127 ILE A CG2 1 +ATOM 973 C CD1 . ILE A 1 127 ? 23.017 -35.395 21.666 1.00 101.42 ? 127 ILE A CD1 1 +ATOM 974 N N . ILE A 1 128 ? 17.513 -35.607 24.380 1.00 69.43 ? 128 ILE A N 1 +ATOM 975 C CA . ILE A 1 128 ? 16.657 -35.886 25.551 1.00 74.33 ? 128 ILE A CA 1 +ATOM 976 C C . ILE A 1 128 ? 16.383 -37.276 26.059 1.00 87.72 ? 128 ILE A C 1 +ATOM 977 O O . ILE A 1 128 ? 15.307 -37.530 26.656 1.00 148.31 ? 128 ILE A O 1 +ATOM 978 C CB . ILE A 1 128 ? 15.272 -35.300 25.346 1.00 99.17 ? 128 ILE A CB 1 +ATOM 979 C CG1 . ILE A 1 128 ? 14.677 -35.724 23.992 1.00 104.10 ? 128 ILE A CG1 1 +ATOM 980 C CG2 . ILE A 1 128 ? 15.329 -33.800 25.346 1.00 114.08 ? 128 ILE A CG2 1 +ATOM 981 C CD1 . ILE A 1 128 ? 13.156 -35.722 23.958 1.00 94.16 ? 128 ILE A CD1 1 +ATOM 982 N N . GLY A 1 129 ? 17.427 -38.073 26.086 1.00 98.46 ? 129 GLY A N 1 +ATOM 983 C CA . GLY A 1 129 ? 17.387 -39.456 26.581 1.00 103.89 ? 129 GLY A CA 1 +ATOM 984 C C . GLY A 1 129 ? 18.134 -40.442 25.718 1.00 103.38 ? 129 GLY A C 1 +ATOM 985 O O . GLY A 1 129 ? 18.175 -40.324 24.487 1.00 102.72 ? 129 GLY A O 1 +ATOM 986 N N . TYR A 1 130 ? 18.830 -41.350 26.394 1.00 106.85 ? 130 TYR A N 1 +ATOM 987 C CA . TYR A 1 130 ? 19.326 -42.565 25.766 1.00 102.75 ? 130 TYR A CA 1 +ATOM 988 C C . TYR A 1 130 ? 19.082 -43.661 26.775 1.00 92.94 ? 130 TYR A C 1 +ATOM 989 O O . TYR A 1 130 ? 19.721 -43.691 27.798 1.00 121.64 ? 130 TYR A O 1 +ATOM 990 C CB . TYR A 1 130 ? 20.830 -42.440 25.429 1.00 88.20 ? 130 TYR A CB 1 +ATOM 991 C CG . TYR A 1 130 ? 21.483 -43.696 24.882 1.00 70.71 ? 130 TYR A CG 1 +ATOM 992 C CD1 . TYR A 1 130 ? 21.600 -44.841 25.657 1.00 77.71 ? 130 TYR A CD1 1 +ATOM 993 C CD2 . TYR A 1 130 ? 21.997 -43.724 23.577 1.00 82.47 ? 130 TYR A CD2 1 +ATOM 994 C CE1 . TYR A 1 130 ? 22.248 -45.973 25.164 1.00 100.43 ? 130 TYR A CE1 1 +ATOM 995 C CE2 . TYR A 1 130 ? 22.593 -44.862 23.055 1.00 104.44 ? 130 TYR A CE2 1 +ATOM 996 C CZ . TYR A 1 130 ? 22.729 -45.978 23.855 1.00 113.58 ? 130 TYR A CZ 1 +ATOM 997 O OH . TYR A 1 130 ? 23.358 -47.085 23.327 1.00 128.73 ? 130 TYR A OH 1 +ATOM 998 N N . GLU A 1 131 ? 18.127 -44.534 26.471 1.00 82.85 ? 131 GLU A N 1 +ATOM 999 C CA . GLU A 1 131 ? 17.856 -45.711 27.282 1.00 82.60 ? 131 GLU A CA 1 +ATOM 1000 C C . GLU A 1 131 ? 18.536 -46.886 26.600 1.00 78.32 ? 131 GLU A C 1 +ATOM 1001 O O . GLU A 1 131 ? 18.581 -46.951 25.372 1.00 79.28 ? 131 GLU A O 1 +ATOM 1002 C CB . GLU A 1 131 ? 16.352 -45.957 27.393 1.00 116.32 ? 131 GLU A CB 1 +ATOM 1003 C CG . GLU A 1 131 ? 15.632 -44.994 28.323 1.00 133.15 ? 131 GLU A CG 1 +ATOM 1004 C CD . GLU A 1 131 ? 16.518 -44.503 29.451 1.00 123.21 ? 131 GLU A CD 1 +ATOM 1005 O OE1 . GLU A 1 131 ? 16.692 -45.246 30.439 1.00 147.78 ? 131 GLU A OE1 1 +ATOM 1006 O OE2 . GLU A 1 131 ? 17.039 -43.372 29.350 1.00 44.14 ? 131 GLU A OE2 1 +ATOM 1007 N N . SER A 1 132 ? 19.078 -47.807 27.387 1.00 100.32 ? 132 SER A N 1 +ATOM 1008 C CA . SER A 1 132 ? 19.893 -48.884 26.808 1.00 110.39 ? 132 SER A CA 1 +ATOM 1009 C C . SER A 1 132 ? 19.278 -50.274 27.043 1.00 117.04 ? 132 SER A C 1 +ATOM 1010 O O . SER A 1 132 ? 18.775 -50.566 28.138 1.00 155.37 ? 132 SER A O 1 +ATOM 1011 C CB . SER A 1 132 ? 21.319 -48.824 27.370 1.00 102.20 ? 132 SER A CB 1 +ATOM 1012 O OG . SER A 1 132 ? 21.605 -49.950 28.193 1.00 126.85 ? 132 SER A OG 1 +ATOM 1013 N N . ASN A 1 133 ? 19.390 -51.147 26.043 1.00 111.82 ? 133 ASN A N 1 +ATOM 1014 C CA . ASN A 1 133 ? 18.696 -52.443 26.051 1.00 141.63 ? 133 ASN A CA 1 +ATOM 1015 C C . ASN A 1 133 ? 17.239 -52.266 26.439 1.00 156.06 ? 133 ASN A C 1 +ATOM 1016 O O . ASN A 1 133 ? 16.744 -52.889 27.384 1.00 161.43 ? 133 ASN A O 1 +ATOM 1017 C CB . ASN A 1 133 ? 19.363 -53.453 26.991 1.00 135.17 ? 133 ASN A CB 1 +ATOM 1018 C CG . ASN A 1 133 ? 20.805 -53.738 26.602 1.00 141.02 ? 133 ASN A CG 1 +ATOM 1019 O OD1 . ASN A 1 133 ? 21.179 -53.693 25.424 1.00 129.47 ? 133 ASN A OD1 1 +ATOM 1020 N ND2 . ASN A 1 133 ? 21.619 -54.039 27.596 1.00 156.98 ? 133 ASN A ND2 1 +ATOM 1021 N N . VAL A 1 134 ? 16.555 -51.429 25.668 1.00 159.98 ? 134 VAL A N 1 +ATOM 1022 C CA . VAL A 1 134 ? 15.137 -51.162 25.868 1.00 136.53 ? 134 VAL A CA 1 +ATOM 1023 C C . VAL A 1 134 ? 14.379 -52.444 25.520 1.00 104.77 ? 134 VAL A C 1 +ATOM 1024 O O . VAL A 1 134 ? 13.389 -52.786 26.167 1.00 66.28 ? 134 VAL A O 1 +ATOM 1025 C CB . VAL A 1 134 ? 14.669 -49.971 24.993 1.00 129.79 ? 134 VAL A CB 1 +ATOM 1026 C CG1 . VAL A 1 134 ? 13.218 -49.641 25.258 1.00 114.69 ? 134 VAL A CG1 1 +ATOM 1027 C CG2 . VAL A 1 134 ? 15.537 -48.740 25.255 1.00 132.37 ? 134 VAL A CG2 1 +ATOM 1028 N N . LYS A 1 135 ? 14.892 -53.170 24.527 1.00 95.99 ? 135 LYS A N 1 +ATOM 1029 C CA . LYS A 1 135 ? 14.493 -54.555 24.314 1.00 97.19 ? 135 LYS A CA 1 +ATOM 1030 C C . LYS A 1 135 ? 15.678 -55.439 24.017 1.00 100.92 ? 135 LYS A C 1 +ATOM 1031 O O . LYS A 1 135 ? 16.746 -54.967 23.582 1.00 105.15 ? 135 LYS A O 1 +ATOM 1032 C CB . LYS A 1 135 ? 13.511 -54.651 23.150 1.00 121.08 ? 135 LYS A CB 1 +ATOM 1033 C CG . LYS A 1 135 ? 12.203 -53.908 23.388 1.00 135.83 ? 135 LYS A CG 1 +ATOM 1034 C CD . LYS A 1 135 ? 11.320 -53.961 22.150 1.00 125.79 ? 135 LYS A CD 1 +ATOM 1035 C CE . LYS A 1 135 ? 10.016 -53.223 22.355 1.00 125.10 ? 135 LYS A CE 1 +ATOM 1036 N NZ . LYS A 1 135 ? 8.998 -53.681 21.379 1.00 114.45 ? 135 LYS A NZ 1 +ATOM 1037 N N . SER A 1 136 ? 15.475 -56.738 24.210 1.00 118.50 ? 136 SER A N 1 +ATOM 1038 C CA . SER A 1 136 ? 16.519 -57.721 23.940 1.00 141.06 ? 136 SER A CA 1 +ATOM 1039 C C . SER A 1 136 ? 15.947 -59.133 23.829 1.00 113.77 ? 136 SER A C 1 +ATOM 1040 O O . SER A 1 136 ? 14.900 -59.422 24.397 1.00 91.30 ? 136 SER A O 1 +ATOM 1041 C CB . SER A 1 136 ? 17.616 -57.655 25.016 1.00 155.57 ? 136 SER A CB 1 +ATOM 1042 O OG . SER A 1 136 ? 17.835 -58.927 25.621 1.00 212.49 ? 136 SER A OG 1 +ATOM 1043 N N . GLY A 1 137 ? 16.662 -60.011 23.124 1.00 102.14 ? 137 GLY A N 1 +ATOM 1044 C CA . GLY A 1 137 ? 16.259 -61.414 23.019 1.00 103.34 ? 137 GLY A CA 1 +ATOM 1045 C C . GLY A 1 137 ? 17.306 -62.325 22.422 1.00 113.75 ? 137 GLY A C 1 +ATOM 1046 O O . GLY A 1 137 ? 18.393 -61.883 22.059 1.00 104.50 ? 137 GLY A O 1 +ATOM 1047 N N . GLY A 1 138 ? 17.000 -63.620 22.355 1.00 154.03 ? 138 GLY A N 1 +ATOM 1048 C CA . GLY A 1 138 ? 17.954 -64.612 21.841 1.00 193.04 ? 138 GLY A CA 1 +ATOM 1049 C C . GLY A 1 138 ? 17.331 -65.968 21.539 1.00 164.21 ? 138 GLY A C 1 +ATOM 1050 O O . GLY A 1 138 ? 16.412 -66.400 22.240 1.00 91.34 ? 138 GLY A O 1 +ATOM 1051 N N . VAL A 1 139 ? 17.859 -66.634 20.508 1.00 139.51 ? 139 VAL A N 1 +ATOM 1052 C CA . VAL A 1 139 ? 17.441 -67.978 20.161 1.00 121.94 ? 139 VAL A CA 1 +ATOM 1053 C C . VAL A 1 139 ? 18.645 -68.816 19.758 1.00 122.28 ? 139 VAL A C 1 +ATOM 1054 O O . VAL A 1 139 ? 19.416 -68.445 18.866 1.00 100.51 ? 139 VAL A O 1 +ATOM 1055 C CB . VAL A 1 139 ? 16.450 -67.974 18.994 1.00 142.62 ? 139 VAL A CB 1 +ATOM 1056 C CG1 . VAL A 1 139 ? 16.128 -69.399 18.576 1.00 144.02 ? 139 VAL A CG1 1 +ATOM 1057 C CG2 . VAL A 1 139 ? 15.172 -67.224 19.366 1.00 167.73 ? 139 VAL A CG2 1 +ATOM 1058 N N . GLY A 1 140 ? 18.789 -69.973 20.400 1.00 140.46 ? 140 GLY A N 1 +ATOM 1059 C CA . GLY A 1 140 ? 19.917 -70.870 20.134 1.00 142.31 ? 140 GLY A CA 1 +ATOM 1060 C C . GLY A 1 140 ? 19.607 -72.335 20.356 1.00 136.99 ? 140 GLY A C 1 +ATOM 1061 O O . GLY A 1 140 ? 18.857 -72.693 21.268 1.00 153.27 ? 140 GLY A O 1 +ATOM 1062 N N . ALA A 1 141 ? 20.235 -73.190 19.557 1.00 136.24 ? 141 ALA A N 1 +ATOM 1063 C CA . ALA A 1 141 ? 20.135 -74.628 19.763 1.00 138.75 ? 141 ALA A CA 1 +ATOM 1064 C C . ALA A 1 141 ? 21.454 -75.344 19.470 1.00 141.23 ? 141 ALA A C 1 +ATOM 1065 O O . ALA A 1 141 ? 22.176 -75.007 18.531 1.00 127.72 ? 141 ALA A O 1 +ATOM 1066 C CB . ALA A 1 141 ? 19.011 -75.202 18.916 1.00 131.08 ? 141 ALA A CB 1 +ATOM 1067 N N . ARG A 1 142 ? 21.765 -76.337 20.292 1.00 147.26 ? 142 ARG A N 1 +ATOM 1068 C CA . ARG A 1 142 ? 22.851 -77.247 19.988 1.00 170.49 ? 142 ARG A CA 1 +ATOM 1069 C C . ARG A 1 142 ? 22.345 -78.678 20.081 1.00 197.85 ? 142 ARG A C 1 +ATOM 1070 O O . ARG A 1 142 ? 21.477 -78.987 20.900 1.00 147.28 ? 142 ARG A O 1 +ATOM 1071 C CB . ARG A 1 142 ? 24.041 -77.036 20.925 1.00 175.13 ? 142 ARG A CB 1 +ATOM 1072 C CG . ARG A 1 142 ? 25.239 -77.911 20.570 1.00 168.22 ? 142 ARG A CG 1 +ATOM 1073 C CD . ARG A 1 142 ? 26.552 -77.161 20.674 1.00 181.96 ? 142 ARG A CD 1 +ATOM 1074 N NE . ARG A 1 142 ? 27.012 -77.103 22.057 1.00 191.98 ? 142 ARG A NE 1 +ATOM 1075 C CZ . ARG A 1 142 ? 27.813 -76.163 22.555 1.00 181.25 ? 142 ARG A CZ 1 +ATOM 1076 N NH1 . ARG A 1 142 ? 28.279 -75.189 21.784 1.00 160.38 ? 142 ARG A NH1 1 +ATOM 1077 N NH2 . ARG A 1 142 ? 28.175 -76.214 23.834 1.00 193.75 ? 142 ARG A NH2 1 +ATOM 1078 N N . TYR A 1 143 ? 22.854 -79.525 19.188 1.00 242.84 ? 143 TYR A N 1 +ATOM 1079 C CA . TYR A 1 143 ? 22.347 -80.882 19.023 1.00 231.49 ? 143 TYR A CA 1 +ATOM 1080 C C . TYR A 1 143 ? 23.503 -81.890 19.004 1.00 194.86 ? 143 TYR A C 1 +ATOM 1081 O O . TYR A 1 143 ? 23.949 -82.325 17.941 1.00 168.45 ? 143 TYR A O 1 +ATOM 1082 C CB . TYR A 1 143 ? 21.520 -80.970 17.732 1.00 241.30 ? 143 TYR A CB 1 +ATOM 1083 C CG . TYR A 1 143 ? 20.835 -82.288 17.555 1.00 230.57 ? 143 TYR A CG 1 +ATOM 1084 C CD1 . TYR A 1 143 ? 19.760 -82.643 18.361 1.00 203.49 ? 143 TYR A CD1 1 +ATOM 1085 C CD2 . TYR A 1 143 ? 21.275 -83.193 16.601 1.00 227.52 ? 143 TYR A CD2 1 +ATOM 1086 C CE1 . TYR A 1 143 ? 19.132 -83.863 18.217 1.00 196.36 ? 143 TYR A CE1 1 +ATOM 1087 C CE2 . TYR A 1 143 ? 20.651 -84.415 16.444 1.00 220.50 ? 143 TYR A CE2 1 +ATOM 1088 C CZ . TYR A 1 143 ? 19.584 -84.746 17.257 1.00 203.78 ? 143 TYR A CZ 1 +ATOM 1089 O OH . TYR A 1 143 ? 18.967 -85.966 17.115 1.00 192.02 ? 143 TYR A OH 1 +ATOM 1090 N N . GLY A 1 145 ? 28.312 -82.798 17.316 1.00 176.57 ? 145 GLY A N 1 +ATOM 1091 C CA . GLY A 1 145 ? 27.465 -81.862 18.041 1.00 172.94 ? 145 GLY A CA 1 +ATOM 1092 C C . GLY A 1 145 ? 27.506 -80.443 17.483 1.00 181.83 ? 145 GLY A C 1 +ATOM 1093 O O . GLY A 1 145 ? 28.523 -79.712 17.552 1.00 190.54 ? 145 GLY A O 1 +ATOM 1094 N N . ILE A 1 146 ? 26.368 -80.058 16.924 1.00 183.33 ? 146 ILE A N 1 +ATOM 1095 C CA . ILE A 1 146 ? 26.291 -78.896 16.035 1.00 184.68 ? 146 ILE A CA 1 +ATOM 1096 C C . ILE A 1 146 ? 25.362 -77.849 16.650 1.00 195.55 ? 146 ILE A C 1 +ATOM 1097 O O . ILE A 1 146 ? 24.323 -78.194 17.204 1.00 183.12 ? 146 ILE A O 1 +ATOM 1098 C CB . ILE A 1 146 ? 25.765 -79.290 14.634 1.00 162.31 ? 146 ILE A CB 1 +ATOM 1099 C CG1 . ILE A 1 146 ? 26.348 -80.641 14.198 1.00 150.43 ? 146 ILE A CG1 1 +ATOM 1100 C CG2 . ILE A 1 146 ? 26.100 -78.213 13.612 1.00 145.83 ? 146 ILE A CG2 1 +ATOM 1101 C CD1 . ILE A 1 146 ? 25.439 -81.822 14.473 1.00 147.79 ? 146 ILE A CD1 1 +ATOM 1102 N N . GLY A 1 147 ? 25.739 -76.573 16.581 1.00 194.21 ? 147 GLY A N 1 +ATOM 1103 C CA . GLY A 1 147 ? 24.942 -75.531 17.231 1.00 168.96 ? 147 GLY A CA 1 +ATOM 1104 C C . GLY A 1 147 ? 24.995 -74.162 16.582 1.00 155.74 ? 147 GLY A C 1 +ATOM 1105 O O . GLY A 1 147 ? 25.975 -73.801 15.930 1.00 109.90 ? 147 GLY A O 1 +ATOM 1106 N N . ALA A 1 148 ? 23.946 -73.382 16.817 1.00 155.78 ? 148 ALA A N 1 +ATOM 1107 C CA . ALA A 1 148 ? 23.939 -71.980 16.435 1.00 146.48 ? 148 ALA A CA 1 +ATOM 1108 C C . ALA A 1 148 ? 23.094 -71.157 17.409 1.00 142.29 ? 148 ALA A C 1 +ATOM 1109 O O . ALA A 1 148 ? 22.348 -71.701 18.235 1.00 134.79 ? 148 ALA A O 1 +ATOM 1110 C CB . ALA A 1 148 ? 23.425 -71.829 15.013 1.00 150.63 ? 148 ALA A CB 1 +ATOM 1111 N N . ASP A 1 149 ? 23.229 -69.839 17.320 1.00 143.28 ? 149 ASP A N 1 +ATOM 1112 C CA . ASP A 1 149 ? 22.501 -68.924 18.199 1.00 167.32 ? 149 ASP A CA 1 +ATOM 1113 C C . ASP A 1 149 ? 22.529 -67.527 17.651 1.00 169.80 ? 149 ASP A C 1 +ATOM 1114 O O . ASP A 1 149 ? 23.541 -67.128 17.084 1.00 151.65 ? 149 ASP A O 1 +ATOM 1115 C CB . ASP A 1 149 ? 23.193 -68.949 19.586 1.00 151.59 ? 149 ASP A CB 1 +ATOM 1116 C CG . ASP A 1 149 ? 22.793 -67.807 20.525 1.00 150.17 ? 149 ASP A CG 1 +ATOM 1117 O OD1 . ASP A 1 149 ? 23.314 -66.692 20.355 1.00 194.11 ? 149 ASP A OD1 1 +ATOM 1118 O OD2 . ASP A 1 149 ? 22.137 -68.057 21.568 1.00 138.61 ? 149 ASP A OD2 1 +ATOM 1119 N N . THR A 1 150 ? 21.426 -66.789 17.808 1.00 152.18 ? 150 THR A N 1 +ATOM 1120 C CA . THR A 1 150 ? 21.496 -65.341 17.660 1.00 150.27 ? 150 THR A CA 1 +ATOM 1121 C C . THR A 1 150 ? 21.004 -64.661 18.927 1.00 145.62 ? 150 THR A C 1 +ATOM 1122 O O . THR A 1 150 ? 20.247 -65.233 19.711 1.00 109.87 ? 150 THR A O 1 +ATOM 1123 C CB . THR A 1 150 ? 20.676 -64.807 16.473 1.00 144.64 ? 150 THR A CB 1 +ATOM 1124 O OG1 . THR A 1 150 ? 19.301 -65.165 16.639 1.00 172.07 ? 150 THR A OG1 1 +ATOM 1125 C CG2 . THR A 1 150 ? 21.199 -65.352 15.157 1.00 132.61 ? 150 THR A CG2 1 +ATOM 1126 N N . GLN A 1 151 ? 21.500 -63.451 19.143 1.00 129.11 ? 151 GLN A N 1 +ATOM 1127 C CA . GLN A 1 151 ? 21.065 -62.618 20.239 1.00 114.57 ? 151 GLN A CA 1 +ATOM 1128 C C . GLN A 1 151 ? 20.907 -61.213 19.718 1.00 103.85 ? 151 GLN A C 1 +ATOM 1129 O O . GLN A 1 151 ? 21.710 -60.783 18.906 1.00 113.96 ? 151 GLN A O 1 +ATOM 1130 C CB . GLN A 1 151 ? 22.104 -62.678 21.360 1.00 118.52 ? 151 GLN A CB 1 +ATOM 1131 C CG . GLN A 1 151 ? 22.084 -63.995 22.116 1.00 144.93 ? 151 GLN A CG 1 +ATOM 1132 C CD . GLN A 1 151 ? 23.365 -64.236 22.888 1.00 169.56 ? 151 GLN A CD 1 +ATOM 1133 O OE1 . GLN A 1 151 ? 23.942 -63.309 23.446 1.00 120.81 ? 151 GLN A OE1 1 +ATOM 1134 N NE2 . GLN A 1 151 ? 23.838 -65.481 22.886 1.00 202.21 ? 151 GLN A NE2 1 +ATOM 1135 N N . TYR A 1 152 ? 19.913 -60.478 20.204 1.00 91.02 ? 152 TYR A N 1 +ATOM 1136 C CA . TYR A 1 152 ? 19.781 -59.081 19.820 1.00 98.08 ? 152 TYR A CA 1 +ATOM 1137 C C . TYR A 1 152 ? 19.451 -58.160 20.974 1.00 122.17 ? 152 TYR A C 1 +ATOM 1138 O O . TYR A 1 152 ? 18.821 -58.571 21.952 1.00 139.54 ? 152 TYR A O 1 +ATOM 1139 C CB . TYR A 1 152 ? 18.736 -58.959 18.749 1.00 102.01 ? 152 TYR A CB 1 +ATOM 1140 C CG . TYR A 1 152 ? 17.403 -58.387 19.190 1.00 107.14 ? 152 TYR A CG 1 +ATOM 1141 C CD1 . TYR A 1 152 ? 16.571 -59.061 20.087 1.00 84.93 ? 152 TYR A CD1 1 +ATOM 1142 C CD2 . TYR A 1 152 ? 16.904 -57.252 18.580 1.00 118.27 ? 152 TYR A CD2 1 +ATOM 1143 C CE1 . TYR A 1 152 ? 15.331 -58.557 20.439 1.00 72.44 ? 152 TYR A CE1 1 +ATOM 1144 C CE2 . TYR A 1 152 ? 15.627 -56.789 18.859 1.00 107.73 ? 152 TYR A CE2 1 +ATOM 1145 C CZ . TYR A 1 152 ? 14.855 -57.435 19.802 1.00 84.65 ? 152 TYR A CZ 1 +ATOM 1146 O OH . TYR A 1 152 ? 13.600 -56.948 20.089 1.00 116.59 ? 152 TYR A OH 1 +ATOM 1147 N N . GLN A 1 153 ? 19.936 -56.923 20.886 1.00 139.31 ? 153 GLN A N 1 +ATOM 1148 C CA . GLN A 1 153 ? 19.543 -55.889 21.831 1.00 150.05 ? 153 GLN A CA 1 +ATOM 1149 C C . GLN A 1 153 ? 19.246 -54.597 21.082 1.00 134.11 ? 153 GLN A C 1 +ATOM 1150 O O . GLN A 1 153 ? 19.777 -54.369 19.993 1.00 152.29 ? 153 GLN A O 1 +ATOM 1151 C CB . GLN A 1 153 ? 20.649 -55.666 22.871 1.00 159.66 ? 153 GLN A CB 1 +ATOM 1152 C CG . GLN A 1 153 ? 20.918 -56.857 23.802 1.00 157.93 ? 153 GLN A CG 1 +ATOM 1153 C CD . GLN A 1 153 ? 22.136 -56.610 24.709 1.00 180.55 ? 153 GLN A CD 1 +ATOM 1154 O OE1 . GLN A 1 153 ? 22.959 -55.719 24.447 1.00 196.73 ? 153 GLN A OE1 1 +ATOM 1155 N NE2 . GLN A 1 153 ? 22.216 -57.346 25.815 1.00 194.28 ? 153 GLN A NE2 1 +ATOM 1156 N N . LEU A 1 154 ? 18.386 -53.758 21.653 1.00 110.38 ? 154 LEU A N 1 +ATOM 1157 C CA . LEU A 1 154 ? 18.165 -52.439 21.074 1.00 107.54 ? 154 LEU A CA 1 +ATOM 1158 C C . LEU A 1 154 ? 17.949 -51.346 22.115 1.00 116.28 ? 154 LEU A C 1 +ATOM 1159 O O . LEU A 1 154 ? 17.312 -51.557 23.164 1.00 100.98 ? 154 LEU A O 1 +ATOM 1160 C CB . LEU A 1 154 ? 17.003 -52.468 20.084 1.00 93.56 ? 154 LEU A CB 1 +ATOM 1161 C CG . LEU A 1 154 ? 15.615 -52.617 20.707 1.00 105.37 ? 154 LEU A CG 1 +ATOM 1162 C CD1 . LEU A 1 154 ? 14.937 -51.276 20.902 1.00 91.00 ? 154 LEU A CD1 1 +ATOM 1163 C CD2 . LEU A 1 154 ? 14.770 -53.527 19.832 1.00 146.96 ? 154 LEU A CD2 1 +ATOM 1164 N N . ASP A 1 155 ? 18.411 -50.150 21.742 1.00 125.98 ? 155 ASP A N 1 +ATOM 1165 C CA . ASP A 1 155 ? 18.503 -48.980 22.623 1.00 108.96 ? 155 ASP A CA 1 +ATOM 1166 C C . ASP A 1 155 ? 17.690 -47.841 22.013 1.00 89.69 ? 155 ASP A C 1 +ATOM 1167 O O . ASP A 1 155 ? 17.380 -47.859 20.823 1.00 82.69 ? 155 ASP A O 1 +ATOM 1168 C CB . ASP A 1 155 ? 19.968 -48.539 22.759 1.00 106.99 ? 155 ASP A CB 1 +ATOM 1169 C CG . ASP A 1 155 ? 20.905 -49.703 23.033 1.00 116.58 ? 155 ASP A CG 1 +ATOM 1170 O OD1 . ASP A 1 155 ? 21.254 -50.434 22.072 1.00 130.83 ? 155 ASP A OD1 1 +ATOM 1171 O OD2 . ASP A 1 155 ? 21.282 -49.894 24.203 1.00 120.33 ? 155 ASP A OD2 1 +ATOM 1172 N N . GLN A 1 156 ? 17.339 -46.854 22.824 1.00 82.69 ? 156 GLN A N 1 +ATOM 1173 C CA . GLN A 1 156 ? 16.580 -45.711 22.323 1.00 89.46 ? 156 GLN A CA 1 +ATOM 1174 C C . GLN A 1 156 ? 17.437 -44.418 22.358 1.00 78.34 ? 156 GLN A C 1 +ATOM 1175 O O . GLN A 1 156 ? 18.281 -44.259 23.215 1.00 67.62 ? 156 GLN A O 1 +ATOM 1176 C CB . GLN A 1 156 ? 15.256 -45.587 23.113 1.00 79.02 ? 156 GLN A CB 1 +ATOM 1177 C CG . GLN A 1 156 ? 14.245 -44.631 22.512 1.00 82.04 ? 156 GLN A CG 1 +ATOM 1178 C CD . GLN A 1 156 ? 12.813 -44.917 22.955 1.00 98.74 ? 156 GLN A CD 1 +ATOM 1179 O OE1 . GLN A 1 156 ? 12.581 -45.718 23.851 1.00 98.54 ? 156 GLN A OE1 1 +ATOM 1180 N NE2 . GLN A 1 156 ? 11.851 -44.213 22.351 1.00 101.27 ? 156 GLN A NE2 1 +ATOM 1181 N N . ILE A 1 157 ? 17.117 -43.469 21.491 1.00 67.43 ? 157 ILE A N 1 +ATOM 1182 C CA . ILE A 1 157 ? 17.665 -42.126 21.578 1.00 49.66 ? 157 ILE A CA 1 +ATOM 1183 C C . ILE A 1 157 ? 16.621 -41.086 21.078 1.00 50.84 ? 157 ILE A C 1 +ATOM 1184 O O . ILE A 1 157 ? 15.791 -41.372 20.210 1.00 50.83 ? 157 ILE A O 1 +ATOM 1185 C CB . ILE A 1 157 ? 18.899 -42.074 20.724 1.00 50.95 ? 157 ILE A CB 1 +ATOM 1186 C CG1 . ILE A 1 157 ? 19.806 -40.945 21.188 1.00 89.21 ? 157 ILE A CG1 1 +ATOM 1187 C CG2 . ILE A 1 157 ? 18.524 -41.862 19.277 1.00 57.17 ? 157 ILE A CG2 1 +ATOM 1188 C CD1 . ILE A 1 157 ? 21.165 -40.936 20.517 1.00 100.90 ? 157 ILE A CD1 1 +ATOM 1189 N N . ALA A 1 158 ? 16.511 -39.960 21.763 1.00 50.94 ? 158 ALA A N 1 +ATOM 1190 C CA . ALA A 1 158 ? 15.485 -38.998 21.405 1.00 50.11 ? 158 ALA A CA 1 +ATOM 1191 C C . ALA A 1 158 ? 16.114 -37.624 21.332 1.00 44.40 ? 158 ALA A C 1 +ATOM 1192 O O . ALA A 1 158 ? 17.059 -37.303 22.059 1.00 27.64 ? 158 ALA A O 1 +ATOM 1193 C CB . ALA A 1 158 ? 14.311 -39.024 22.393 1.00 59.59 ? 158 ALA A CB 1 +ATOM 1194 N N . VAL A 1 159 ? 15.530 -36.797 20.493 1.00 46.62 ? 159 VAL A N 1 +ATOM 1195 C CA . VAL A 1 159 ? 16.053 -35.470 20.265 1.00 56.60 ? 159 VAL A CA 1 +ATOM 1196 C C . VAL A 1 159 ? 14.927 -34.434 20.188 1.00 70.70 ? 159 VAL A C 1 +ATOM 1197 O O . VAL A 1 159 ? 13.914 -34.628 19.513 1.00 88.60 ? 159 VAL A O 1 +ATOM 1198 C CB . VAL A 1 159 ? 16.854 -35.451 18.963 1.00 58.02 ? 159 VAL A CB 1 +ATOM 1199 C CG1 . VAL A 1 159 ? 16.993 -34.043 18.425 1.00 63.25 ? 159 VAL A CG1 1 +ATOM 1200 C CG2 . VAL A 1 159 ? 18.203 -36.068 19.176 1.00 54.32 ? 159 VAL A CG2 1 +ATOM 1201 N N . ASN A 1 160 ? 15.083 -33.373 20.955 1.00 66.48 ? 160 ASN A N 1 +ATOM 1202 C CA . ASN A 1 160 ? 14.220 -32.237 20.846 1.00 81.55 ? 160 ASN A CA 1 +ATOM 1203 C C . ASN A 1 160 ? 14.927 -31.228 19.920 1.00 80.36 ? 160 ASN A C 1 +ATOM 1204 O O . ASN A 1 160 ? 16.091 -30.899 20.118 1.00 73.82 ? 160 ASN A O 1 +ATOM 1205 C CB . ASN A 1 160 ? 13.976 -31.630 22.242 1.00 106.27 ? 160 ASN A CB 1 +ATOM 1206 C CG . ASN A 1 160 ? 13.102 -30.357 22.202 1.00 129.66 ? 160 ASN A CG 1 +ATOM 1207 O OD1 . ASN A 1 160 ? 13.409 -29.410 21.480 1.00 104.84 ? 160 ASN A OD1 1 +ATOM 1208 N ND2 . ASN A 1 160 ? 12.134 -30.271 23.107 1.00 134.29 ? 160 ASN A ND2 1 +ATOM 1209 N N . LEU A 1 161 ? 14.194 -30.705 18.950 1.00 70.19 ? 161 LEU A N 1 +ATOM 1210 C CA . LEU A 1 161 ? 14.562 -29.460 18.301 1.00 47.49 ? 161 LEU A CA 1 +ATOM 1211 C C . LEU A 1 161 ? 13.427 -28.482 18.427 1.00 42.84 ? 161 LEU A C 1 +ATOM 1212 O O . LEU A 1 161 ? 12.238 -28.842 18.395 1.00 64.01 ? 161 LEU A O 1 +ATOM 1213 C CB . LEU A 1 161 ? 14.851 -29.729 16.843 1.00 57.28 ? 161 LEU A CB 1 +ATOM 1214 C CG . LEU A 1 161 ? 16.048 -30.637 16.580 1.00 70.81 ? 161 LEU A CG 1 +ATOM 1215 C CD1 . LEU A 1 161 ? 16.110 -30.988 15.096 1.00 94.37 ? 161 LEU A CD1 1 +ATOM 1216 C CD2 . LEU A 1 161 ? 17.320 -29.940 17.035 1.00 73.68 ? 161 LEU A CD2 1 +ATOM 1217 N N . ARG A 1 162 ? 13.741 -27.220 18.449 1.00 44.04 ? 162 ARG A N 1 +ATOM 1218 C CA . ARG A 1 162 ? 12.689 -26.221 18.557 1.00 64.34 ? 162 ARG A CA 1 +ATOM 1219 C C . ARG A 1 162 ? 13.053 -24.859 17.978 1.00 71.05 ? 162 ARG A C 1 +ATOM 1220 O O . ARG A 1 162 ? 14.130 -24.307 18.274 1.00 123.34 ? 162 ARG A O 1 +ATOM 1221 C CB . ARG A 1 162 ? 12.187 -26.104 20.011 1.00 65.01 ? 162 ARG A CB 1 +ATOM 1222 C CG . ARG A 1 162 ? 13.178 -25.629 21.052 1.00 79.52 ? 162 ARG A CG 1 +ATOM 1223 C CD . ARG A 1 162 ? 12.437 -25.167 22.318 1.00 87.66 ? 162 ARG A CD 1 +ATOM 1224 N NE . ARG A 1 162 ? 13.228 -24.490 23.350 1.00 74.46 ? 162 ARG A NE 1 +ATOM 1225 C CZ . ARG A 1 162 ? 13.982 -25.146 24.230 1.00 94.06 ? 162 ARG A CZ 1 +ATOM 1226 N NH1 . ARG A 1 162 ? 14.153 -26.479 24.157 1.00 95.33 ? 162 ARG A NH1 1 +ATOM 1227 N NH2 . ARG A 1 162 ? 14.643 -24.459 25.134 1.00 141.96 ? 162 ARG A NH2 1 +ATOM 1228 N N . VAL A 1 163 ? 12.149 -24.323 17.156 1.00 59.32 ? 163 VAL A N 1 +ATOM 1229 C CA . VAL A 1 163 ? 12.314 -22.999 16.560 1.00 69.06 ? 163 VAL A CA 1 +ATOM 1230 C C . VAL A 1 163 ? 11.833 -21.881 17.464 1.00 58.19 ? 163 VAL A C 1 +ATOM 1231 O O . VAL A 1 163 ? 10.683 -21.882 17.877 1.00 83.52 ? 163 VAL A O 1 +ATOM 1232 C CB . VAL A 1 163 ? 11.492 -22.857 15.282 1.00 84.79 ? 163 VAL A CB 1 +ATOM 1233 C CG1 . VAL A 1 163 ? 11.684 -21.435 14.697 1.00 88.16 ? 163 VAL A CG1 1 +ATOM 1234 C CG2 . VAL A 1 163 ? 11.829 -23.969 14.287 1.00 82.65 ? 163 VAL A CG2 1 +ATOM 1235 N N . VAL A 1 164 ? 12.720 -20.937 17.744 1.00 57.92 ? 164 VAL A N 1 +ATOM 1236 C CA . VAL A 1 164 ? 12.446 -19.811 18.634 1.00 44.70 ? 164 VAL A CA 1 +ATOM 1237 C C . VAL A 1 164 ? 12.492 -18.581 17.831 1.00 41.67 ? 164 VAL A C 1 +ATOM 1238 O O . VAL A 1 164 ? 13.426 -18.386 17.047 1.00 59.54 ? 164 VAL A O 1 +ATOM 1239 C CB . VAL A 1 164 ? 13.510 -19.675 19.742 1.00 34.98 ? 164 VAL A CB 1 +ATOM 1240 C CG1 . VAL A 1 164 ? 13.205 -18.492 20.592 1.00 29.85 ? 164 VAL A CG1 1 +ATOM 1241 C CG2 . VAL A 1 164 ? 13.509 -20.938 20.597 1.00 46.26 ? 164 VAL A CG2 1 +ATOM 1242 N N . ASN A 1 165 ? 11.486 -17.763 18.013 1.00 52.91 ? 165 ASN A N 1 +ATOM 1243 C CA . ASN A 1 165 ? 11.435 -16.475 17.331 1.00 83.76 ? 165 ASN A CA 1 +ATOM 1244 C C . ASN A 1 165 ? 12.260 -15.401 18.064 1.00 82.33 ? 165 ASN A C 1 +ATOM 1245 O O . ASN A 1 165 ? 11.968 -15.063 19.208 1.00 59.02 ? 165 ASN A O 1 +ATOM 1246 C CB . ASN A 1 165 ? 9.994 -15.980 17.172 1.00 75.74 ? 165 ASN A CB 1 +ATOM 1247 C CG . ASN A 1 165 ? 9.892 -14.816 16.215 1.00 80.79 ? 165 ASN A CG 1 +ATOM 1248 O OD1 . ASN A 1 165 ? 10.884 -14.420 15.592 1.00 115.85 ? 165 ASN A OD1 1 +ATOM 1249 N ND2 . ASN A 1 165 ? 8.775 -14.136 16.257 1.00 107.46 ? 165 ASN A ND2 1 +ATOM 1250 N N . VAL A 1 166 ? 13.295 -14.890 17.389 1.00 88.43 ? 166 VAL A N 1 +ATOM 1251 C CA . VAL A 1 166 ? 14.233 -13.937 17.981 1.00 77.08 ? 166 VAL A CA 1 +ATOM 1252 C C . VAL A 1 166 ? 13.482 -12.712 18.395 1.00 61.94 ? 166 VAL A C 1 +ATOM 1253 O O . VAL A 1 166 ? 13.759 -12.142 19.431 1.00 72.49 ? 166 VAL A O 1 +ATOM 1254 C CB . VAL A 1 166 ? 15.350 -13.566 16.980 1.00 88.86 ? 166 VAL A CB 1 +ATOM 1255 C CG1 . VAL A 1 166 ? 15.930 -12.194 17.269 1.00 83.97 ? 166 VAL A CG1 1 +ATOM 1256 C CG2 . VAL A 1 166 ? 16.429 -14.652 16.957 1.00 80.21 ? 166 VAL A CG2 1 +ATOM 1257 N N . SER A 1 167 ? 12.509 -12.327 17.593 1.00 59.80 ? 167 SER A N 1 +ATOM 1258 C CA . SER A 1 167 ? 11.847 -11.053 17.784 1.00 83.89 ? 167 SER A CA 1 +ATOM 1259 C C . SER A 1 167 ? 10.936 -11.045 19.009 1.00 77.29 ? 167 SER A C 1 +ATOM 1260 O O . SER A 1 167 ? 10.468 -9.975 19.418 1.00 80.64 ? 167 SER A O 1 +ATOM 1261 C CB . SER A 1 167 ? 11.068 -10.688 16.512 1.00 111.63 ? 167 SER A CB 1 +ATOM 1262 O OG . SER A 1 167 ? 11.868 -10.896 15.351 1.00 153.56 ? 167 SER A OG 1 +ATOM 1263 N N . THR A 1 168 ? 10.631 -12.226 19.550 1.00 68.93 ? 168 THR A N 1 +ATOM 1264 C CA . THR A 1 168 ? 9.680 -12.315 20.664 1.00 73.25 ? 168 THR A CA 1 +ATOM 1265 C C . THR A 1 168 ? 10.110 -13.252 21.774 1.00 72.11 ? 168 THR A C 1 +ATOM 1266 O O . THR A 1 168 ? 9.821 -13.058 22.969 1.00 60.67 ? 168 THR A O 1 +ATOM 1267 C CB . THR A 1 168 ? 8.279 -12.769 20.189 1.00 70.64 ? 168 THR A CB 1 +ATOM 1268 O OG1 . THR A 1 168 ? 8.403 -13.944 19.400 1.00 46.20 ? 168 THR A OG1 1 +ATOM 1269 C CG2 . THR A 1 168 ? 7.601 -11.657 19.372 1.00 85.39 ? 168 THR A CG2 1 +ATOM 1270 N N . GLY A 1 169 ? 10.707 -14.351 21.374 1.00 73.56 ? 169 GLY A N 1 +ATOM 1271 C CA . GLY A 1 169 ? 11.010 -15.393 22.346 1.00 83.82 ? 169 GLY A CA 1 +ATOM 1272 C C . GLY A 1 169 ? 9.979 -16.508 22.296 1.00 50.40 ? 169 GLY A C 1 +ATOM 1273 O O . GLY A 1 169 ? 10.160 -17.522 22.947 1.00 36.11 ? 169 GLY A O 1 +ATOM 1274 N N . GLU A 1 170 ? 8.875 -16.252 21.613 1.00 41.84 ? 170 GLU A N 1 +ATOM 1275 C CA . GLU A 1 170 ? 7.883 -17.275 21.406 1.00 49.74 ? 170 GLU A CA 1 +ATOM 1276 C C . GLU A 1 170 ? 8.620 -18.395 20.776 1.00 46.00 ? 170 GLU A C 1 +ATOM 1277 O O . GLU A 1 170 ? 9.317 -18.231 19.784 1.00 61.88 ? 170 GLU A O 1 +ATOM 1278 C CB . GLU A 1 170 ? 6.747 -16.791 20.484 1.00 69.93 ? 170 GLU A CB 1 +ATOM 1279 C CG . GLU A 1 170 ? 5.704 -15.905 21.170 1.00 115.39 ? 170 GLU A CG 1 +ATOM 1280 C CD . GLU A 1 170 ? 5.154 -14.767 20.308 1.00 147.11 ? 170 GLU A CD 1 +ATOM 1281 O OE1 . GLU A 1 170 ? 5.719 -14.499 19.236 1.00 156.81 ? 170 GLU A OE1 1 +ATOM 1282 O OE2 . GLU A 1 170 ? 4.194 -14.087 20.741 1.00 173.57 ? 170 GLU A OE2 1 +ATOM 1283 N N . ILE A 1 171 ? 8.455 -19.575 21.321 1.00 60.91 ? 171 ILE A N 1 +ATOM 1284 C CA . ILE A 1 171 ? 8.813 -20.766 20.583 1.00 71.25 ? 171 ILE A CA 1 +ATOM 1285 C C . ILE A 1 171 ? 7.788 -20.967 19.455 1.00 72.20 ? 171 ILE A C 1 +ATOM 1286 O O . ILE A 1 171 ? 6.598 -21.011 19.706 1.00 74.17 ? 171 ILE A O 1 +ATOM 1287 C CB . ILE A 1 171 ? 8.864 -21.998 21.507 1.00 68.94 ? 171 ILE A CB 1 +ATOM 1288 C CG1 . ILE A 1 171 ? 10.062 -21.874 22.469 1.00 55.20 ? 171 ILE A CG1 1 +ATOM 1289 C CG2 . ILE A 1 171 ? 8.936 -23.276 20.668 1.00 61.60 ? 171 ILE A CG2 1 +ATOM 1290 C CD1 . ILE A 1 171 ? 9.967 -22.801 23.641 1.00 48.66 ? 171 ILE A CD1 1 +ATOM 1291 N N . LEU A 1 172 ? 8.256 -21.057 18.212 1.00 76.72 ? 172 LEU A N 1 +ATOM 1292 C CA . LEU A 1 172 ? 7.346 -21.205 17.073 1.00 63.95 ? 172 LEU A CA 1 +ATOM 1293 C C . LEU A 1 172 ? 7.031 -22.675 16.747 1.00 55.51 ? 172 LEU A C 1 +ATOM 1294 O O . LEU A 1 172 ? 6.187 -22.978 15.906 1.00 53.80 ? 172 LEU A O 1 +ATOM 1295 C CB . LEU A 1 172 ? 7.890 -20.454 15.836 1.00 72.58 ? 172 LEU A CB 1 +ATOM 1296 C CG . LEU A 1 172 ? 7.557 -18.965 15.626 1.00 92.22 ? 172 LEU A CG 1 +ATOM 1297 C CD1 . LEU A 1 172 ? 7.278 -18.362 16.985 1.00 100.35 ? 172 LEU A CD1 1 +ATOM 1298 C CD2 . LEU A 1 172 ? 8.521 -18.111 14.808 1.00 102.34 ? 172 LEU A CD2 1 +ATOM 1299 N N . SER A 1 173 ? 7.827 -23.573 17.307 1.00 65.10 ? 173 SER A N 1 +ATOM 1300 C CA . SER A 1 173 ? 7.719 -24.978 17.004 1.00 71.31 ? 173 SER A CA 1 +ATOM 1301 C C . SER A 1 173 ? 8.616 -25.798 17.922 1.00 67.65 ? 173 SER A C 1 +ATOM 1302 O O . SER A 1 173 ? 9.807 -25.566 18.015 1.00 57.34 ? 173 SER A O 1 +ATOM 1303 C CB . SER A 1 173 ? 8.096 -25.286 15.541 1.00 83.15 ? 173 SER A CB 1 +ATOM 1304 O OG . SER A 1 173 ? 8.258 -26.690 15.356 1.00 125.88 ? 173 SER A OG 1 +ATOM 1305 N N . SER A 1 174 ? 8.039 -26.821 18.544 1.00 86.05 ? 174 SER A N 1 +ATOM 1306 C CA . SER A 1 174 ? 8.815 -27.862 19.222 1.00 78.17 ? 174 SER A CA 1 +ATOM 1307 C C . SER A 1 174 ? 8.496 -29.227 18.618 1.00 74.52 ? 174 SER A C 1 +ATOM 1308 O O . SER A 1 174 ? 7.341 -29.546 18.376 1.00 51.67 ? 174 SER A O 1 +ATOM 1309 C CB . SER A 1 174 ? 8.516 -27.876 20.733 1.00 77.44 ? 174 SER A CB 1 +ATOM 1310 O OG . SER A 1 174 ? 9.439 -28.680 21.464 1.00 50.25 ? 174 SER A OG 1 +ATOM 1311 N N . VAL A 1 175 ? 9.540 -30.030 18.404 1.00 84.58 ? 175 VAL A N 1 +ATOM 1312 C CA . VAL A 1 175 ? 9.385 -31.397 17.876 1.00 79.90 ? 175 VAL A CA 1 +ATOM 1313 C C . VAL A 1 175 ? 10.268 -32.407 18.592 1.00 58.92 ? 175 VAL A C 1 +ATOM 1314 O O . VAL A 1 175 ? 11.389 -32.065 19.030 1.00 66.50 ? 175 VAL A O 1 +ATOM 1315 C CB . VAL A 1 175 ? 9.712 -31.441 16.381 1.00 94.94 ? 175 VAL A CB 1 +ATOM 1316 C CG1 . VAL A 1 175 ? 8.751 -30.568 15.593 1.00 108.14 ? 175 VAL A CG1 1 +ATOM 1317 C CG2 . VAL A 1 175 ? 11.133 -30.974 16.113 1.00 98.62 ? 175 VAL A CG2 1 +ATOM 1318 N N . ASN A 1 176 ? 9.757 -33.619 18.734 1.00 48.63 ? 176 ASN A N 1 +ATOM 1319 C CA . ASN A 1 176 ? 10.408 -34.637 19.590 1.00 57.90 ? 176 ASN A CA 1 +ATOM 1320 C C . ASN A 1 176 ? 10.645 -35.980 18.904 1.00 48.62 ? 176 ASN A C 1 +ATOM 1321 O O . ASN A 1 176 ? 9.741 -36.794 18.859 1.00 41.62 ? 176 ASN A O 1 +ATOM 1322 C CB . ASN A 1 176 ? 9.551 -34.868 20.850 1.00 62.17 ? 176 ASN A CB 1 +ATOM 1323 C CG . ASN A 1 176 ? 10.068 -34.081 22.047 1.00 89.31 ? 176 ASN A CG 1 +ATOM 1324 O OD1 . ASN A 1 176 ? 10.859 -33.154 21.864 1.00 79.52 ? 176 ASN A OD1 1 +ATOM 1325 N ND2 . ASN A 1 176 ? 9.624 -34.417 23.280 1.00 124.01 ? 176 ASN A ND2 1 +ATOM 1326 N N . THR A 1 177 ? 11.812 -36.161 18.300 1.00 50.43 ? 177 THR A N 1 +ATOM 1327 C CA . THR A 1 177 ? 12.033 -37.323 17.461 1.00 59.48 ? 177 THR A CA 1 +ATOM 1328 C C . THR A 1 177 ? 12.756 -38.370 18.245 1.00 71.04 ? 177 THR A C 1 +ATOM 1329 O O . THR A 1 177 ? 13.381 -38.085 19.262 1.00 60.21 ? 177 THR A O 1 +ATOM 1330 C CB . THR A 1 177 ? 12.851 -36.997 16.190 1.00 72.44 ? 177 THR A CB 1 +ATOM 1331 O OG1 . THR A 1 177 ? 14.188 -36.635 16.545 1.00 48.49 ? 177 THR A OG1 1 +ATOM 1332 C CG2 . THR A 1 177 ? 12.214 -35.832 15.383 1.00 80.97 ? 177 THR A CG2 1 +ATOM 1333 N N . SER A 1 178 ? 12.654 -39.600 17.766 1.00 87.75 ? 178 SER A N 1 +ATOM 1334 C CA . SER A 1 178 ? 13.212 -40.744 18.479 1.00 82.02 ? 178 SER A CA 1 +ATOM 1335 C C . SER A 1 178 ? 13.683 -41.789 17.503 1.00 68.74 ? 178 SER A C 1 +ATOM 1336 O O . SER A 1 178 ? 13.181 -41.905 16.376 1.00 78.12 ? 178 SER A O 1 +ATOM 1337 C CB . SER A 1 178 ? 12.175 -41.365 19.417 1.00 91.71 ? 178 SER A CB 1 +ATOM 1338 O OG . SER A 1 178 ? 12.580 -42.650 19.858 1.00 74.66 ? 178 SER A OG 1 +ATOM 1339 N N . LYS A 1 179 ? 14.644 -42.573 17.938 1.00 63.56 ? 179 LYS A N 1 +ATOM 1340 C CA . LYS A 1 179 ? 15.263 -43.520 17.032 1.00 78.03 ? 179 LYS A CA 1 +ATOM 1341 C C . LYS A 1 179 ? 15.865 -44.682 17.818 1.00 78.61 ? 179 LYS A C 1 +ATOM 1342 O O . LYS A 1 179 ? 16.356 -44.518 18.941 1.00 58.34 ? 179 LYS A O 1 +ATOM 1343 C CB . LYS A 1 179 ? 16.333 -42.807 16.200 1.00 78.57 ? 179 LYS A CB 1 +ATOM 1344 C CG . LYS A 1 179 ? 16.461 -43.303 14.777 1.00 83.59 ? 179 LYS A CG 1 +ATOM 1345 C CD . LYS A 1 179 ? 17.533 -44.370 14.686 1.00 95.27 ? 179 LYS A CD 1 +ATOM 1346 C CE . LYS A 1 179 ? 17.547 -44.989 13.307 1.00 114.23 ? 179 LYS A CE 1 +ATOM 1347 N NZ . LYS A 1 179 ? 18.370 -46.221 13.268 1.00 130.65 ? 179 LYS A NZ 1 +ATOM 1348 N N . THR A 1 180 ? 15.809 -45.861 17.218 1.00 84.35 ? 180 THR A N 1 +ATOM 1349 C CA . THR A 1 180 ? 16.229 -47.066 17.898 1.00 86.42 ? 180 THR A CA 1 +ATOM 1350 C C . THR A 1 180 ? 17.559 -47.561 17.320 1.00 84.85 ? 180 THR A C 1 +ATOM 1351 O O . THR A 1 180 ? 17.739 -47.660 16.100 1.00 84.03 ? 180 THR A O 1 +ATOM 1352 C CB . THR A 1 180 ? 15.144 -48.167 17.842 1.00 83.21 ? 180 THR A CB 1 +ATOM 1353 O OG1 . THR A 1 180 ? 15.760 -49.453 17.980 1.00 87.70 ? 180 THR A OG1 1 +ATOM 1354 C CG2 . THR A 1 180 ? 14.365 -48.108 16.529 1.00 78.36 ? 180 THR A CG2 1 +ATOM 1355 N N . ILE A 1 181 ? 18.473 -47.906 18.214 1.00 86.46 ? 181 ILE A N 1 +ATOM 1356 C CA . ILE A 1 181 ? 19.766 -48.439 17.817 1.00 94.83 ? 181 ILE A CA 1 +ATOM 1357 C C . ILE A 1 181 ? 19.775 -49.975 17.944 1.00 88.20 ? 181 ILE A C 1 +ATOM 1358 O O . ILE A 1 181 ? 19.652 -50.514 19.051 1.00 95.60 ? 181 ILE A O 1 +ATOM 1359 C CB . ILE A 1 181 ? 20.906 -47.812 18.667 1.00 115.66 ? 181 ILE A CB 1 +ATOM 1360 C CG1 . ILE A 1 181 ? 20.824 -46.283 18.639 1.00 105.07 ? 181 ILE A CG1 1 +ATOM 1361 C CG2 . ILE A 1 181 ? 22.286 -48.242 18.173 1.00 135.47 ? 181 ILE A CG2 1 +ATOM 1362 C CD1 . ILE A 1 181 ? 20.612 -45.661 19.999 1.00 104.48 ? 181 ILE A CD1 1 +ATOM 1363 N N . LEU A 1 182 ? 19.999 -50.656 16.819 1.00 73.60 ? 182 LEU A N 1 +ATOM 1364 C CA . LEU A 1 182 ? 19.992 -52.112 16.767 1.00 77.02 ? 182 LEU A CA 1 +ATOM 1365 C C . LEU A 1 182 ? 21.364 -52.748 16.930 1.00 87.45 ? 182 LEU A C 1 +ATOM 1366 O O . LEU A 1 182 ? 22.356 -52.310 16.335 1.00 81.91 ? 182 LEU A O 1 +ATOM 1367 C CB . LEU A 1 182 ? 19.402 -52.575 15.441 1.00 94.00 ? 182 LEU A CB 1 +ATOM 1368 C CG . LEU A 1 182 ? 19.327 -54.091 15.231 1.00 89.81 ? 182 LEU A CG 1 +ATOM 1369 C CD1 . LEU A 1 182 ? 18.442 -54.795 16.260 1.00 72.51 ? 182 LEU A CD1 1 +ATOM 1370 C CD2 . LEU A 1 182 ? 18.842 -54.353 13.811 1.00 99.99 ? 182 LEU A CD2 1 +ATOM 1371 N N . SER A 1 183 ? 21.397 -53.844 17.689 1.00 127.25 ? 183 SER A N 1 +ATOM 1372 C CA . SER A 1 183 ? 22.602 -54.667 17.832 1.00 139.54 ? 183 SER A CA 1 +ATOM 1373 C C . SER A 1 183 ? 22.248 -56.159 17.804 1.00 128.96 ? 183 SER A C 1 +ATOM 1374 O O . SER A 1 183 ? 21.217 -56.570 18.347 1.00 114.90 ? 183 SER A O 1 +ATOM 1375 C CB . SER A 1 183 ? 23.303 -54.331 19.145 1.00 137.87 ? 183 SER A CB 1 +ATOM 1376 O OG . SER A 1 183 ? 23.223 -52.939 19.420 1.00 140.67 ? 183 SER A OG 1 +ATOM 1377 N N . TYR A 1 184 ? 23.085 -56.958 17.147 1.00 110.33 ? 184 TYR A N 1 +ATOM 1378 C CA . TYR A 1 184 ? 22.869 -58.397 17.115 1.00 114.92 ? 184 TYR A CA 1 +ATOM 1379 C C . TYR A 1 184 ? 24.150 -59.221 16.960 1.00 139.00 ? 184 TYR A C 1 +ATOM 1380 O O . TYR A 1 184 ? 25.170 -58.752 16.443 1.00 138.19 ? 184 TYR A O 1 +ATOM 1381 C CB . TYR A 1 184 ? 21.866 -58.767 16.030 1.00 100.32 ? 184 TYR A CB 1 +ATOM 1382 C CG . TYR A 1 184 ? 22.289 -58.327 14.650 1.00 100.70 ? 184 TYR A CG 1 +ATOM 1383 C CD1 . TYR A 1 184 ? 22.058 -57.028 14.183 1.00 125.76 ? 184 TYR A CD1 1 +ATOM 1384 C CD2 . TYR A 1 184 ? 22.888 -59.218 13.796 1.00 94.98 ? 184 TYR A CD2 1 +ATOM 1385 C CE1 . TYR A 1 184 ? 22.452 -56.642 12.906 1.00 131.92 ? 184 TYR A CE1 1 +ATOM 1386 C CE2 . TYR A 1 184 ? 23.274 -58.847 12.521 1.00 100.46 ? 184 TYR A CE2 1 +ATOM 1387 C CZ . TYR A 1 184 ? 23.063 -57.562 12.078 1.00 99.88 ? 184 TYR A CZ 1 +ATOM 1388 O OH . TYR A 1 184 ? 23.397 -57.212 10.786 1.00 69.46 ? 184 TYR A OH 1 +ATOM 1389 N N . GLU A 1 185 ? 24.073 -60.459 17.448 1.00 160.73 ? 185 GLU A N 1 +ATOM 1390 C CA . GLU A 1 185 ? 25.200 -61.392 17.467 1.00 162.08 ? 185 GLU A CA 1 +ATOM 1391 C C . GLU A 1 185 ? 24.771 -62.750 16.954 1.00 164.00 ? 185 GLU A C 1 +ATOM 1392 O O . GLU A 1 185 ? 24.001 -63.448 17.608 1.00 167.80 ? 185 GLU A O 1 +ATOM 1393 C CB . GLU A 1 185 ? 25.795 -61.584 18.868 1.00 163.93 ? 185 GLU A CB 1 +ATOM 1394 C CG . GLU A 1 185 ? 25.942 -60.333 19.705 1.00 180.61 ? 185 GLU A CG 1 +ATOM 1395 C CD . GLU A 1 185 ? 26.723 -60.609 20.978 1.00 179.47 ? 185 GLU A CD 1 +ATOM 1396 O OE1 . GLU A 1 185 ? 27.103 -61.782 21.206 1.00 124.98 ? 185 GLU A OE1 1 +ATOM 1397 O OE2 . GLU A 1 185 ? 26.989 -59.646 21.727 1.00 208.24 ? 185 GLU A OE2 1 +ATOM 1398 N N . VAL A 1 186 ? 25.298 -63.121 15.794 1.00 154.11 ? 186 VAL A N 1 +ATOM 1399 C CA . VAL A 1 186 ? 25.051 -64.420 15.204 1.00 141.39 ? 186 VAL A CA 1 +ATOM 1400 C C . VAL A 1 186 ? 26.263 -65.322 15.419 1.00 154.13 ? 186 VAL A C 1 +ATOM 1401 O O . VAL A 1 186 ? 27.406 -64.881 15.302 1.00 148.65 ? 186 VAL A O 1 +ATOM 1402 C CB . VAL A 1 186 ? 24.767 -64.288 13.700 1.00 143.64 ? 186 VAL A CB 1 +ATOM 1403 C CG1 . VAL A 1 186 ? 24.309 -65.622 13.133 1.00 167.12 ? 186 VAL A CG1 1 +ATOM 1404 C CG2 . VAL A 1 186 ? 23.715 -63.216 13.447 1.00 142.31 ? 186 VAL A CG2 1 +ATOM 1405 N N . GLN A 1 187 ? 26.006 -66.581 15.760 1.00 181.03 ? 187 GLN A N 1 +ATOM 1406 C CA . GLN A 1 187 ? 27.082 -67.519 16.068 1.00 194.25 ? 187 GLN A CA 1 +ATOM 1407 C C . GLN A 1 187 ? 26.715 -68.934 15.661 1.00 215.07 ? 187 GLN A C 1 +ATOM 1408 O O . GLN A 1 187 ? 25.594 -69.377 15.903 1.00 198.71 ? 187 GLN A O 1 +ATOM 1409 C CB . GLN A 1 187 ? 27.369 -67.500 17.573 1.00 175.77 ? 187 GLN A CB 1 +ATOM 1410 C CG . GLN A 1 187 ? 28.336 -66.431 18.036 1.00 172.13 ? 187 GLN A CG 1 +ATOM 1411 C CD . GLN A 1 187 ? 28.189 -66.139 19.516 1.00 168.40 ? 187 GLN A CD 1 +ATOM 1412 O OE1 . GLN A 1 187 ? 27.975 -67.052 20.316 1.00 145.40 ? 187 GLN A OE1 1 +ATOM 1413 N NE2 . GLN A 1 187 ? 28.276 -64.857 19.889 1.00 165.56 ? 187 GLN A NE2 1 +ATOM 1414 N N . ALA A 1 188 ? 27.678 -69.644 15.075 1.00 203.11 ? 188 ALA A N 1 +ATOM 1415 C CA . ALA A 1 188 ? 27.482 -71.047 14.731 1.00 150.43 ? 188 ALA A CA 1 +ATOM 1416 C C . ALA A 1 188 ? 28.766 -71.831 14.976 1.00 162.90 ? 188 ALA A C 1 +ATOM 1417 O O . ALA A 1 188 ? 29.865 -71.345 14.709 1.00 177.81 ? 188 ALA A O 1 +ATOM 1418 C CB . ALA A 1 188 ? 27.039 -71.177 13.287 1.00 125.29 ? 188 ALA A CB 1 +ATOM 1419 N N . GLY A 1 189 ? 28.630 -73.033 15.514 1.00 171.87 ? 189 GLY A N 1 +ATOM 1420 C CA . GLY A 1 189 ? 29.782 -73.882 15.791 1.00 192.84 ? 189 GLY A CA 1 +ATOM 1421 C C . GLY A 1 189 ? 29.502 -75.359 15.571 1.00 201.50 ? 189 GLY A C 1 +ATOM 1422 O O . GLY A 1 189 ? 28.441 -75.854 15.946 1.00 201.79 ? 189 GLY A O 1 +ATOM 1423 N N . VAL A 1 190 ? 30.468 -76.060 14.978 1.00 188.15 ? 190 VAL A N 1 +ATOM 1424 C CA . VAL A 1 190 ? 30.383 -77.500 14.795 1.00 161.79 ? 190 VAL A CA 1 +ATOM 1425 C C . VAL A 1 190 ? 31.465 -78.206 15.632 1.00 181.38 ? 190 VAL A C 1 +ATOM 1426 O O . VAL A 1 190 ? 32.628 -77.787 15.664 1.00 152.95 ? 190 VAL A O 1 +ATOM 1427 C CB . VAL A 1 190 ? 30.537 -77.878 13.315 1.00 134.60 ? 190 VAL A CB 1 +ATOM 1428 C CG1 . VAL A 1 190 ? 30.177 -79.342 13.110 1.00 135.93 ? 190 VAL A CG1 1 +ATOM 1429 C CG2 . VAL A 1 190 ? 29.679 -76.974 12.441 1.00 115.41 ? 190 VAL A CG2 1 +ATOM 1430 N N . PHE A 1 191 ? 31.073 -79.266 16.332 1.00 199.11 ? 191 PHE A N 1 +ATOM 1431 C CA . PHE A 1 191 ? 31.950 -79.911 17.312 1.00 192.62 ? 191 PHE A CA 1 +ATOM 1432 C C . PHE A 1 191 ? 31.920 -81.418 17.143 1.00 201.16 ? 191 PHE A C 1 +ATOM 1433 O O . PHE A 1 191 ? 30.849 -82.033 17.017 1.00 243.63 ? 191 PHE A O 1 +ATOM 1434 C CB . PHE A 1 191 ? 31.514 -79.551 18.736 1.00 175.28 ? 191 PHE A CB 1 +ATOM 1435 C CG . PHE A 1 191 ? 32.589 -79.744 19.772 1.00 185.39 ? 191 PHE A CG 1 +ATOM 1436 C CD1 . PHE A 1 191 ? 32.967 -81.018 20.177 1.00 173.05 ? 191 PHE A CD1 1 +ATOM 1437 C CD2 . PHE A 1 191 ? 33.219 -78.649 20.349 1.00 195.77 ? 191 PHE A CD2 1 +ATOM 1438 C CE1 . PHE A 1 191 ? 33.952 -81.198 21.135 1.00 148.41 ? 191 PHE A CE1 1 +ATOM 1439 C CE2 . PHE A 1 191 ? 34.195 -78.822 21.316 1.00 182.03 ? 191 PHE A CE2 1 +ATOM 1440 C CZ . PHE A 1 191 ? 34.563 -80.100 21.708 1.00 159.74 ? 191 PHE A CZ 1 +ATOM 1441 N N . ARG A 1 192 ? 33.100 -82.025 17.156 1.00 183.55 ? 192 ARG A N 1 +ATOM 1442 C CA . ARG A 1 192 ? 33.203 -83.441 16.854 1.00 169.56 ? 192 ARG A CA 1 +ATOM 1443 C C . ARG A 1 192 ? 34.554 -84.032 17.203 1.00 137.81 ? 192 ARG A C 1 +ATOM 1444 O O . ARG A 1 192 ? 34.743 -85.240 17.065 1.00 137.54 ? 192 ARG A O 1 +ATOM 1445 C CB . ARG A 1 192 ? 32.906 -83.701 15.369 1.00 161.07 ? 192 ARG A CB 1 +ATOM 1446 C CG . ARG A 1 192 ? 31.613 -84.459 15.108 1.00 156.81 ? 192 ARG A CG 1 +ATOM 1447 C CD . ARG A 1 192 ? 30.932 -84.071 13.798 1.00 137.18 ? 192 ARG A CD 1 +ATOM 1448 N NE . ARG A 1 192 ? 29.493 -84.258 13.947 1.00 154.04 ? 192 ARG A NE 1 +ATOM 1449 C CZ . ARG A 1 192 ? 28.806 -85.332 13.559 1.00 152.96 ? 192 ARG A CZ 1 +ATOM 1450 N NH1 . ARG A 1 192 ? 29.383 -86.309 12.871 1.00 153.81 ? 192 ARG A NH1 1 +ATOM 1451 N NH2 . ARG A 1 192 ? 27.511 -85.403 13.829 1.00 150.58 ? 192 ARG A NH2 1 +ATOM 1452 N N . LEU A 1 200 ? 37.478 -82.566 15.952 1.00 125.30 ? 200 LEU A N 1 +ATOM 1453 C CA . LEU A 1 200 ? 37.013 -81.499 15.067 1.00 138.73 ? 200 LEU A CA 1 +ATOM 1454 C C . LEU A 1 200 ? 36.177 -80.464 15.823 1.00 186.32 ? 200 LEU A C 1 +ATOM 1455 O O . LEU A 1 200 ? 35.062 -80.757 16.275 1.00 181.23 ? 200 LEU A O 1 +ATOM 1456 C CB . LEU A 1 200 ? 36.175 -82.061 13.915 1.00 111.39 ? 200 LEU A CB 1 +ATOM 1457 C CG . LEU A 1 200 ? 35.485 -80.993 13.044 1.00 128.14 ? 200 LEU A CG 1 +ATOM 1458 C CD1 . LEU A 1 200 ? 36.255 -80.770 11.750 1.00 114.82 ? 200 LEU A CD1 1 +ATOM 1459 C CD2 . LEU A 1 200 ? 34.014 -81.311 12.765 1.00 144.52 ? 200 LEU A CD2 1 +ATOM 1460 N N . GLU A 1 201 ? 36.698 -79.239 15.907 1.00 218.25 ? 201 GLU A N 1 +ATOM 1461 C CA . GLU A 1 201 ? 35.883 -78.065 16.221 1.00 196.23 ? 201 GLU A CA 1 +ATOM 1462 C C . GLU A 1 201 ? 35.965 -77.036 15.095 1.00 172.24 ? 201 GLU A C 1 +ATOM 1463 O O . GLU A 1 201 ? 36.987 -76.924 14.425 1.00 177.50 ? 201 GLU A O 1 +ATOM 1464 C CB . GLU A 1 201 ? 36.339 -77.426 17.530 1.00 184.46 ? 201 GLU A CB 1 +ATOM 1465 C CG . GLU A 1 201 ? 35.279 -76.528 18.145 1.00 200.81 ? 201 GLU A CG 1 +ATOM 1466 C CD . GLU A 1 201 ? 35.721 -75.886 19.448 1.00 210.46 ? 201 GLU A CD 1 +ATOM 1467 O OE1 . GLU A 1 201 ? 36.202 -76.611 20.345 1.00 221.47 ? 201 GLU A OE1 1 +ATOM 1468 O OE2 . GLU A 1 201 ? 35.569 -74.653 19.584 1.00 216.96 ? 201 GLU A OE2 1 +ATOM 1469 N N . GLY A 1 202 ? 34.871 -76.317 14.869 1.00 151.55 ? 202 GLY A N 1 +ATOM 1470 C CA . GLY A 1 202 ? 34.856 -75.211 13.924 1.00 172.16 ? 202 GLY A CA 1 +ATOM 1471 C C . GLY A 1 202 ? 33.803 -74.183 14.296 1.00 217.08 ? 202 GLY A C 1 +ATOM 1472 O O . GLY A 1 202 ? 32.629 -74.520 14.469 1.00 276.09 ? 202 GLY A O 1 +ATOM 1473 N N . GLU A 1 203 ? 34.217 -72.924 14.429 1.00 208.37 ? 203 GLU A N 1 +ATOM 1474 C CA . GLU A 1 203 ? 33.307 -71.864 14.863 1.00 167.82 ? 203 GLU A CA 1 +ATOM 1475 C C . GLU A 1 203 ? 33.343 -70.625 13.967 1.00 174.65 ? 203 GLU A C 1 +ATOM 1476 O O . GLU A 1 203 ? 34.415 -70.143 13.585 1.00 136.89 ? 203 GLU A O 1 +ATOM 1477 C CB . GLU A 1 203 ? 33.614 -71.459 16.303 1.00 154.23 ? 203 GLU A CB 1 +ATOM 1478 C CG . GLU A 1 203 ? 33.318 -72.562 17.314 1.00 159.57 ? 203 GLU A CG 1 +ATOM 1479 C CD . GLU A 1 203 ? 33.528 -72.151 18.766 1.00 181.70 ? 203 GLU A CD 1 +ATOM 1480 O OE1 . GLU A 1 203 ? 34.037 -71.034 19.008 1.00 176.37 ? 203 GLU A OE1 1 +ATOM 1481 O OE2 . GLU A 1 203 ? 33.199 -72.962 19.667 1.00 209.94 ? 203 GLU A OE2 1 +ATOM 1482 N N . VAL A 1 204 ? 32.153 -70.107 13.672 1.00 184.00 ? 204 VAL A N 1 +ATOM 1483 C CA . VAL A 1 204 ? 31.989 -68.811 13.023 1.00 145.83 ? 204 VAL A CA 1 +ATOM 1484 C C . VAL A 1 204 ? 31.121 -67.920 13.916 1.00 132.50 ? 204 VAL A C 1 +ATOM 1485 O O . VAL A 1 204 ? 30.106 -68.357 14.469 1.00 122.02 ? 204 VAL A O 1 +ATOM 1486 C CB . VAL A 1 204 ? 31.350 -68.966 11.628 1.00 126.22 ? 204 VAL A CB 1 +ATOM 1487 C CG1 . VAL A 1 204 ? 30.841 -67.632 11.096 1.00 124.41 ? 204 VAL A CG1 1 +ATOM 1488 C CG2 . VAL A 1 204 ? 32.357 -69.578 10.669 1.00 120.22 ? 204 VAL A CG2 1 +ATOM 1489 N N . GLY A 1 205 ? 31.546 -66.674 14.064 1.00 126.89 ? 205 GLY A N 1 +ATOM 1490 C CA . GLY A 1 205 ? 30.782 -65.686 14.807 1.00 139.74 ? 205 GLY A CA 1 +ATOM 1491 C C . GLY A 1 205 ? 30.760 -64.344 14.092 1.00 165.32 ? 205 GLY A C 1 +ATOM 1492 O O . GLY A 1 205 ? 31.712 -63.986 13.385 1.00 226.61 ? 205 GLY A O 1 +ATOM 1493 N N . TYR A 1 206 ? 29.669 -63.605 14.264 1.00 145.06 ? 206 TYR A N 1 +ATOM 1494 C CA . TYR A 1 206 ? 29.549 -62.256 13.712 1.00 119.48 ? 206 TYR A CA 1 +ATOM 1495 C C . TYR A 1 206 ? 28.687 -61.389 14.615 1.00 129.98 ? 206 TYR A C 1 +ATOM 1496 O O . TYR A 1 206 ? 27.711 -61.861 15.172 1.00 115.68 ? 206 TYR A O 1 +ATOM 1497 C CB . TYR A 1 206 ? 28.927 -62.298 12.322 1.00 103.72 ? 206 TYR A CB 1 +ATOM 1498 C CG . TYR A 1 206 ? 28.716 -60.936 11.704 1.00 107.58 ? 206 TYR A CG 1 +ATOM 1499 C CD1 . TYR A 1 206 ? 29.786 -60.206 11.168 1.00 106.06 ? 206 TYR A CD1 1 +ATOM 1500 C CD2 . TYR A 1 206 ? 27.446 -60.377 11.641 1.00 119.14 ? 206 TYR A CD2 1 +ATOM 1501 C CE1 . TYR A 1 206 ? 29.599 -58.955 10.595 1.00 108.56 ? 206 TYR A CE1 1 +ATOM 1502 C CE2 . TYR A 1 206 ? 27.247 -59.135 11.060 1.00 117.34 ? 206 TYR A CE2 1 +ATOM 1503 C CZ . TYR A 1 206 ? 28.316 -58.426 10.535 1.00 120.79 ? 206 TYR A CZ 1 +ATOM 1504 O OH . TYR A 1 206 ? 28.090 -57.190 9.963 1.00 106.99 ? 206 TYR A OH 1 +ATOM 1505 N N . THR A 1 207 ? 29.072 -60.127 14.784 1.00 154.81 ? 207 THR A N 1 +ATOM 1506 C CA . THR A 1 207 ? 28.311 -59.193 15.616 1.00 142.58 ? 207 THR A CA 1 +ATOM 1507 C C . THR A 1 207 ? 28.220 -57.825 14.945 1.00 128.64 ? 207 THR A C 1 +ATOM 1508 O O . THR A 1 207 ? 29.213 -57.317 14.393 1.00 108.83 ? 207 THR A O 1 +ATOM 1509 C CB . THR A 1 207 ? 28.941 -59.010 17.013 1.00 145.53 ? 207 THR A CB 1 +ATOM 1510 O OG1 . THR A 1 207 ? 30.256 -58.460 16.883 1.00 147.10 ? 207 THR A OG1 1 +ATOM 1511 C CG2 . THR A 1 207 ? 29.041 -60.335 17.741 1.00 160.45 ? 207 THR A CG2 1 +ATOM 1512 N N . SER A 1 208 ? 27.025 -57.243 14.970 1.00 118.24 ? 208 SER A N 1 +ATOM 1513 C CA . SER A 1 208 ? 26.829 -55.940 14.337 1.00 130.66 ? 208 SER A CA 1 +ATOM 1514 C C . SER A 1 208 ? 26.071 -54.974 15.232 1.00 135.55 ? 208 SER A C 1 +ATOM 1515 O O . SER A 1 208 ? 24.981 -55.289 15.714 1.00 105.11 ? 208 SER A O 1 +ATOM 1516 C CB . SER A 1 208 ? 26.106 -56.077 12.995 1.00 138.83 ? 208 SER A CB 1 +ATOM 1517 O OG . SER A 1 208 ? 25.787 -54.789 12.467 1.00 129.44 ? 208 SER A OG 1 +ATOM 1518 N N . ASN A 1 209 ? 26.672 -53.799 15.441 1.00 141.49 ? 209 ASN A N 1 +ATOM 1519 C CA . ASN A 1 209 ? 26.043 -52.689 16.159 1.00 106.21 ? 209 ASN A CA 1 +ATOM 1520 C C . ASN A 1 209 ? 25.781 -51.552 15.204 1.00 97.33 ? 209 ASN A C 1 +ATOM 1521 O O . ASN A 1 209 ? 26.636 -51.199 14.395 1.00 90.58 ? 209 ASN A O 1 +ATOM 1522 C CB . ASN A 1 209 ? 26.949 -52.174 17.264 1.00 86.73 ? 209 ASN A CB 1 +ATOM 1523 C CG . ASN A 1 209 ? 27.087 -53.153 18.395 1.00 102.59 ? 209 ASN A CG 1 +ATOM 1524 O OD1 . ASN A 1 209 ? 26.239 -53.226 19.278 1.00 133.46 ? 209 ASN A OD1 1 +ATOM 1525 N ND2 . ASN A 1 209 ? 28.175 -53.912 18.385 1.00 101.10 ? 209 ASN A ND2 1 +ATOM 1526 N N . GLU A 1 210 ? 24.600 -50.972 15.308 1.00 89.08 ? 210 GLU A N 1 +ATOM 1527 C CA . GLU A 1 210 ? 24.360 -49.708 14.657 1.00 84.52 ? 210 GLU A CA 1 +ATOM 1528 C C . GLU A 1 210 ? 25.248 -48.658 15.323 1.00 84.25 ? 210 GLU A C 1 +ATOM 1529 O O . GLU A 1 210 ? 25.428 -48.650 16.542 1.00 104.84 ? 210 GLU A O 1 +ATOM 1530 C CB . GLU A 1 210 ? 22.885 -49.320 14.786 1.00 98.33 ? 210 GLU A CB 1 +ATOM 1531 C CG . GLU A 1 210 ? 22.247 -48.780 13.516 1.00 124.35 ? 210 GLU A CG 1 +ATOM 1532 C CD . GLU A 1 210 ? 20.713 -48.828 13.552 1.00 123.92 ? 210 GLU A CD 1 +ATOM 1533 O OE1 . GLU A 1 210 ? 20.122 -49.660 14.282 1.00 76.37 ? 210 GLU A OE1 1 +ATOM 1534 O OE2 . GLU A 1 210 ? 20.104 -47.999 12.851 1.00 119.21 ? 210 GLU A OE2 1 +ATOM 1535 N N . PRO A 1 211 ? 25.817 -47.757 14.529 1.00 66.75 ? 211 PRO A N 1 +ATOM 1536 C CA . PRO A 1 211 ? 26.453 -46.602 15.132 1.00 66.75 ? 211 PRO A CA 1 +ATOM 1537 C C . PRO A 1 211 ? 25.461 -45.622 15.790 1.00 55.20 ? 211 PRO A C 1 +ATOM 1538 O O . PRO A 1 211 ? 24.549 -45.130 15.120 1.00 62.75 ? 211 PRO A O 1 +ATOM 1539 C CB . PRO A 1 211 ? 27.187 -45.944 13.939 1.00 64.70 ? 211 PRO A CB 1 +ATOM 1540 C CG . PRO A 1 211 ? 27.233 -46.984 12.882 1.00 59.64 ? 211 PRO A CG 1 +ATOM 1541 C CD . PRO A 1 211 ? 25.962 -47.749 13.074 1.00 66.93 ? 211 PRO A CD 1 +ATOM 1542 N N . VAL A 1 212 ? 25.660 -45.352 17.078 1.00 48.90 ? 212 VAL A N 1 +ATOM 1543 C CA . VAL A 1 212 ? 24.861 -44.375 17.793 1.00 62.22 ? 212 VAL A CA 1 +ATOM 1544 C C . VAL A 1 212 ? 25.025 -42.984 17.164 1.00 78.01 ? 212 VAL A C 1 +ATOM 1545 O O . VAL A 1 212 ? 24.050 -42.239 16.992 1.00 113.75 ? 212 VAL A O 1 +ATOM 1546 C CB . VAL A 1 212 ? 25.266 -44.286 19.278 1.00 71.26 ? 212 VAL A CB 1 +ATOM 1547 C CG1 . VAL A 1 212 ? 24.308 -43.387 20.062 1.00 61.26 ? 212 VAL A CG1 1 +ATOM 1548 C CG2 . VAL A 1 212 ? 25.334 -45.674 19.914 1.00 79.21 ? 212 VAL A CG2 1 +ATOM 1549 N N . MET A 1 213 ? 26.270 -42.636 16.884 1.00 89.95 ? 213 MET A N 1 +ATOM 1550 C CA . MET A 1 213 ? 26.642 -41.567 15.968 1.00 102.63 ? 213 MET A CA 1 +ATOM 1551 C C . MET A 1 213 ? 25.660 -41.335 14.799 1.00 100.95 ? 213 MET A C 1 +ATOM 1552 O O . MET A 1 213 ? 25.165 -40.215 14.559 1.00 95.03 ? 213 MET A O 1 +ATOM 1553 C CB . MET A 1 213 ? 28.007 -41.982 15.414 1.00 122.74 ? 213 MET A CB 1 +ATOM 1554 C CG . MET A 1 213 ? 28.725 -41.001 14.531 1.00 122.88 ? 213 MET A CG 1 +ATOM 1555 S SD . MET A 1 213 ? 30.275 -41.780 14.057 1.00 125.09 ? 213 MET A SD 1 +ATOM 1556 C CE . MET A 1 213 ? 29.913 -42.003 12.337 1.00 125.53 ? 213 MET A CE 1 +ATOM 1557 N N . LEU A 1 214 ? 25.361 -42.416 14.089 1.00 93.64 ? 214 LEU A N 1 +ATOM 1558 C CA . LEU A 1 214 ? 24.645 -42.345 12.816 1.00 114.95 ? 214 LEU A CA 1 +ATOM 1559 C C . LEU A 1 214 ? 23.131 -42.267 13.053 1.00 105.53 ? 214 LEU A C 1 +ATOM 1560 O O . LEU A 1 214 ? 22.397 -41.663 12.275 1.00 81.76 ? 214 LEU A O 1 +ATOM 1561 C CB . LEU A 1 214 ? 24.983 -43.577 11.961 1.00 128.96 ? 214 LEU A CB 1 +ATOM 1562 C CG . LEU A 1 214 ? 25.287 -43.402 10.467 1.00 124.29 ? 214 LEU A CG 1 +ATOM 1563 C CD1 . LEU A 1 214 ? 26.474 -42.480 10.222 1.00 109.49 ? 214 LEU A CD1 1 +ATOM 1564 C CD2 . LEU A 1 214 ? 25.537 -44.766 9.831 1.00 115.74 ? 214 LEU A CD2 1 +ATOM 1565 N N . CYS A 1 215 ? 22.688 -42.837 14.168 1.00 111.49 ? 215 CYS A N 1 +ATOM 1566 C CA . CYS A 1 215 ? 21.286 -42.755 14.594 1.00 112.04 ? 215 CYS A CA 1 +ATOM 1567 C C . CYS A 1 215 ? 20.916 -41.366 15.116 1.00 94.24 ? 215 CYS A C 1 +ATOM 1568 O O . CYS A 1 215 ? 19.843 -40.814 14.785 1.00 98.62 ? 215 CYS A O 1 +ATOM 1569 C CB . CYS A 1 215 ? 21.013 -43.738 15.724 1.00 109.06 ? 215 CYS A CB 1 +ATOM 1570 S SG . CYS A 1 215 ? 21.198 -45.451 15.241 1.00 89.11 ? 215 CYS A SG 1 +ATOM 1571 N N . LEU A 1 216 ? 21.819 -40.802 15.905 1.00 59.68 ? 216 LEU A N 1 +ATOM 1572 C CA . LEU A 1 216 ? 21.703 -39.414 16.265 1.00 71.74 ? 216 LEU A CA 1 +ATOM 1573 C C . LEU A 1 216 ? 21.535 -38.531 15.009 1.00 81.80 ? 216 LEU A C 1 +ATOM 1574 O O . LEU A 1 216 ? 20.628 -37.678 14.948 1.00 88.96 ? 216 LEU A O 1 +ATOM 1575 C CB . LEU A 1 216 ? 22.927 -38.945 17.078 1.00 71.07 ? 216 LEU A CB 1 +ATOM 1576 C CG . LEU A 1 216 ? 22.916 -37.479 17.545 1.00 58.74 ? 216 LEU A CG 1 +ATOM 1577 C CD1 . LEU A 1 216 ? 21.686 -37.145 18.370 1.00 69.01 ? 216 LEU A CD1 1 +ATOM 1578 C CD2 . LEU A 1 216 ? 24.149 -37.160 18.333 1.00 48.64 ? 216 LEU A CD2 1 +ATOM 1579 N N . MET A 1 217 ? 22.424 -38.707 14.029 1.00 76.28 ? 217 MET A N 1 +ATOM 1580 C CA . MET A 1 217 ? 22.416 -37.856 12.847 1.00 82.30 ? 217 MET A CA 1 +ATOM 1581 C C . MET A 1 217 ? 21.090 -37.998 12.105 1.00 75.15 ? 217 MET A C 1 +ATOM 1582 O O . MET A 1 217 ? 20.460 -37.011 11.744 1.00 81.98 ? 217 MET A O 1 +ATOM 1583 C CB . MET A 1 217 ? 23.580 -38.193 11.931 1.00 107.42 ? 217 MET A CB 1 +ATOM 1584 C CG . MET A 1 217 ? 24.292 -36.965 11.357 1.00 136.10 ? 217 MET A CG 1 +ATOM 1585 S SD . MET A 1 217 ? 23.278 -36.075 10.154 1.00 161.53 ? 217 MET A SD 1 +ATOM 1586 C CE . MET A 1 217 ? 24.221 -34.573 9.889 1.00 146.43 ? 217 MET A CE 1 +ATOM 1587 N N . SER A 1 218 ? 20.644 -39.233 11.940 1.00 82.08 ? 218 SER A N 1 +ATOM 1588 C CA . SER A 1 218 ? 19.377 -39.532 11.264 1.00 86.14 ? 218 SER A CA 1 +ATOM 1589 C C . SER A 1 218 ? 18.234 -38.814 11.937 1.00 69.69 ? 218 SER A C 1 +ATOM 1590 O O . SER A 1 218 ? 17.415 -38.180 11.278 1.00 72.50 ? 218 SER A O 1 +ATOM 1591 C CB . SER A 1 218 ? 19.124 -41.055 11.273 1.00 111.35 ? 218 SER A CB 1 +ATOM 1592 O OG . SER A 1 218 ? 18.039 -41.417 10.451 1.00 82.90 ? 218 SER A OG 1 +ATOM 1593 N N . ALA A 1 219 ? 18.163 -38.951 13.255 1.00 67.28 ? 219 ALA A N 1 +ATOM 1594 C CA . ALA A 1 219 ? 17.039 -38.419 14.012 1.00 83.86 ? 219 ALA A CA 1 +ATOM 1595 C C . ALA A 1 219 ? 16.993 -36.887 13.958 1.00 64.05 ? 219 ALA A C 1 +ATOM 1596 O O . ALA A 1 219 ? 15.922 -36.276 13.903 1.00 61.42 ? 219 ALA A O 1 +ATOM 1597 C CB . ALA A 1 219 ? 17.110 -38.910 15.453 1.00 108.92 ? 219 ALA A CB 1 +ATOM 1598 N N . ILE A 1 220 ? 18.160 -36.271 13.933 1.00 65.59 ? 220 ILE A N 1 +ATOM 1599 C CA . ILE A 1 220 ? 18.228 -34.819 13.814 1.00 77.82 ? 220 ILE A CA 1 +ATOM 1600 C C . ILE A 1 220 ? 17.734 -34.337 12.439 1.00 88.11 ? 220 ILE A C 1 +ATOM 1601 O O . ILE A 1 220 ? 16.993 -33.363 12.343 1.00 83.92 ? 220 ILE A O 1 +ATOM 1602 C CB . ILE A 1 220 ? 19.660 -34.308 14.059 1.00 80.98 ? 220 ILE A CB 1 +ATOM 1603 C CG1 . ILE A 1 220 ? 20.036 -34.513 15.540 1.00 69.51 ? 220 ILE A CG1 1 +ATOM 1604 C CG2 . ILE A 1 220 ? 19.797 -32.842 13.635 1.00 70.69 ? 220 ILE A CG2 1 +ATOM 1605 C CD1 . ILE A 1 220 ? 21.526 -34.417 15.818 1.00 80.14 ? 220 ILE A CD1 1 +ATOM 1606 N N . GLU A 1 221 ? 18.111 -35.047 11.379 1.00 105.23 ? 221 GLU A N 1 +ATOM 1607 C CA . GLU A 1 221 ? 17.585 -34.764 10.034 1.00 106.74 ? 221 GLU A CA 1 +ATOM 1608 C C . GLU A 1 221 ? 16.040 -34.817 10.001 1.00 79.12 ? 221 GLU A C 1 +ATOM 1609 O O . GLU A 1 221 ? 15.389 -33.873 9.563 1.00 55.01 ? 221 GLU A O 1 +ATOM 1610 C CB . GLU A 1 221 ? 18.162 -35.766 9.017 1.00 128.93 ? 221 GLU A CB 1 +ATOM 1611 C CG . GLU A 1 221 ? 19.629 -35.528 8.693 1.00 142.17 ? 221 GLU A CG 1 +ATOM 1612 C CD . GLU A 1 221 ? 20.308 -36.718 8.031 1.00 139.06 ? 221 GLU A CD 1 +ATOM 1613 O OE1 . GLU A 1 221 ? 19.998 -37.891 8.376 1.00 94.64 ? 221 GLU A OE1 1 +ATOM 1614 O OE2 . GLU A 1 221 ? 21.182 -36.452 7.171 1.00 139.79 ? 221 GLU A OE2 1 +ATOM 1615 N N . THR A 1 222 ? 15.489 -35.926 10.502 1.00 57.38 ? 222 THR A N 1 +ATOM 1616 C CA . THR A 1 222 ? 14.049 -36.141 10.632 1.00 42.69 ? 222 THR A CA 1 +ATOM 1617 C C . THR A 1 222 ? 13.383 -34.998 11.355 1.00 41.09 ? 222 THR A C 1 +ATOM 1618 O O . THR A 1 222 ? 12.389 -34.451 10.878 1.00 45.75 ? 222 THR A O 1 +ATOM 1619 C CB . THR A 1 222 ? 13.773 -37.425 11.431 1.00 44.03 ? 222 THR A CB 1 +ATOM 1620 O OG1 . THR A 1 222 ? 14.122 -38.587 10.640 1.00 45.35 ? 222 THR A OG1 1 +ATOM 1621 C CG2 . THR A 1 222 ? 12.322 -37.484 11.899 1.00 45.62 ? 222 THR A CG2 1 +ATOM 1622 N N . GLY A 1 223 ? 13.961 -34.607 12.479 1.00 48.85 ? 223 GLY A N 1 +ATOM 1623 C CA . GLY A 1 223 ? 13.508 -33.432 13.205 1.00 71.85 ? 223 GLY A CA 1 +ATOM 1624 C C . GLY A 1 223 ? 13.468 -32.149 12.363 1.00 84.68 ? 223 GLY A C 1 +ATOM 1625 O O . GLY A 1 223 ? 12.523 -31.347 12.468 1.00 70.74 ? 223 GLY A O 1 +ATOM 1626 N N . VAL A 1 224 ? 14.496 -31.944 11.546 1.00 82.09 ? 224 VAL A N 1 +ATOM 1627 C CA . VAL A 1 224 ? 14.567 -30.749 10.729 1.00 79.26 ? 224 VAL A CA 1 +ATOM 1628 C C . VAL A 1 224 ? 13.412 -30.756 9.727 1.00 73.63 ? 224 VAL A C 1 +ATOM 1629 O O . VAL A 1 224 ? 12.779 -29.728 9.487 1.00 73.00 ? 224 VAL A O 1 +ATOM 1630 C CB . VAL A 1 224 ? 15.900 -30.649 9.979 1.00 81.10 ? 224 VAL A CB 1 +ATOM 1631 C CG1 . VAL A 1 224 ? 15.864 -29.502 8.978 1.00 85.71 ? 224 VAL A CG1 1 +ATOM 1632 C CG2 . VAL A 1 224 ? 17.046 -30.467 10.951 1.00 74.67 ? 224 VAL A CG2 1 +ATOM 1633 N N . ILE A 1 225 ? 13.133 -31.915 9.153 1.00 64.18 ? 225 ILE A N 1 +ATOM 1634 C CA . ILE A 1 225 ? 12.031 -32.025 8.212 1.00 78.18 ? 225 ILE A CA 1 +ATOM 1635 C C . ILE A 1 225 ? 10.729 -31.635 8.914 1.00 81.25 ? 225 ILE A C 1 +ATOM 1636 O O . ILE A 1 225 ? 9.970 -30.826 8.375 1.00 65.06 ? 225 ILE A O 1 +ATOM 1637 C CB . ILE A 1 225 ? 11.921 -33.446 7.588 1.00 87.16 ? 225 ILE A CB 1 +ATOM 1638 C CG1 . ILE A 1 225 ? 13.112 -33.702 6.668 1.00 85.76 ? 225 ILE A CG1 1 +ATOM 1639 C CG2 . ILE A 1 225 ? 10.644 -33.590 6.782 1.00 82.52 ? 225 ILE A CG2 1 +ATOM 1640 C CD1 . ILE A 1 225 ? 13.336 -35.170 6.364 1.00 93.62 ? 225 ILE A CD1 1 +ATOM 1641 N N . PHE A 1 226 ? 10.444 -32.261 10.069 1.00 86.41 ? 226 PHE A N 1 +ATOM 1642 C CA . PHE A 1 226 ? 9.184 -32.014 10.814 1.00 80.44 ? 226 PHE A CA 1 +ATOM 1643 C C . PHE A 1 226 ? 9.071 -30.536 11.149 1.00 79.87 ? 226 PHE A C 1 +ATOM 1644 O O . PHE A 1 226 ? 7.977 -29.990 11.175 1.00 81.74 ? 226 PHE A O 1 +ATOM 1645 C CB . PHE A 1 226 ? 9.110 -32.837 12.112 1.00 73.77 ? 226 PHE A CB 1 +ATOM 1646 C CG . PHE A 1 226 ? 8.658 -34.264 11.932 1.00 91.79 ? 226 PHE A CG 1 +ATOM 1647 C CD1 . PHE A 1 226 ? 7.442 -34.555 11.318 1.00 97.23 ? 226 PHE A CD1 1 +ATOM 1648 C CD2 . PHE A 1 226 ? 9.425 -35.325 12.422 1.00 84.46 ? 226 PHE A CD2 1 +ATOM 1649 C CE1 . PHE A 1 226 ? 7.024 -35.872 11.146 1.00 81.46 ? 226 PHE A CE1 1 +ATOM 1650 C CE2 . PHE A 1 226 ? 9.002 -36.634 12.246 1.00 78.67 ? 226 PHE A CE2 1 +ATOM 1651 C CZ . PHE A 1 226 ? 7.810 -36.904 11.594 1.00 70.47 ? 226 PHE A CZ 1 +ATOM 1652 N N . LEU A 1 227 ? 10.210 -29.886 11.378 1.00 92.27 ? 227 LEU A N 1 +ATOM 1653 C CA . LEU A 1 227 ? 10.230 -28.447 11.655 1.00 81.28 ? 227 LEU A CA 1 +ATOM 1654 C C . LEU A 1 227 ? 9.813 -27.653 10.421 1.00 68.14 ? 227 LEU A C 1 +ATOM 1655 O O . LEU A 1 227 ? 9.041 -26.727 10.530 1.00 59.06 ? 227 LEU A O 1 +ATOM 1656 C CB . LEU A 1 227 ? 11.619 -28.040 12.141 1.00 67.12 ? 227 LEU A CB 1 +ATOM 1657 C CG . LEU A 1 227 ? 11.970 -28.406 13.582 1.00 67.63 ? 227 LEU A CG 1 +ATOM 1658 C CD1 . LEU A 1 227 ? 13.433 -28.272 13.953 1.00 77.03 ? 227 LEU A CD1 1 +ATOM 1659 C CD2 . LEU A 1 227 ? 11.139 -27.589 14.553 1.00 86.35 ? 227 LEU A CD2 1 +ATOM 1660 N N . ILE A 1 228 ? 10.340 -28.020 9.260 1.00 63.49 ? 228 ILE A N 1 +ATOM 1661 C CA . ILE A 1 228 ? 10.056 -27.289 8.051 1.00 67.30 ? 228 ILE A CA 1 +ATOM 1662 C C . ILE A 1 228 ? 8.590 -27.449 7.744 1.00 65.75 ? 228 ILE A C 1 +ATOM 1663 O O . ILE A 1 228 ? 7.897 -26.498 7.372 1.00 51.49 ? 228 ILE A O 1 +ATOM 1664 C CB . ILE A 1 228 ? 10.903 -27.777 6.856 1.00 90.51 ? 228 ILE A CB 1 +ATOM 1665 C CG1 . ILE A 1 228 ? 12.388 -27.489 7.092 1.00 95.63 ? 228 ILE A CG1 1 +ATOM 1666 C CG2 . ILE A 1 228 ? 10.480 -27.078 5.566 1.00 98.85 ? 228 ILE A CG2 1 +ATOM 1667 C CD1 . ILE A 1 228 ? 13.328 -28.239 6.163 1.00 112.64 ? 228 ILE A CD1 1 +ATOM 1668 N N . ASN A 1 229 ? 8.132 -28.689 7.775 1.00 79.94 ? 229 ASN A N 1 +ATOM 1669 C CA . ASN A 1 229 ? 6.740 -28.996 7.408 1.00 97.11 ? 229 ASN A CA 1 +ATOM 1670 C C . ASN A 1 229 ? 5.820 -28.221 8.347 1.00 75.80 ? 229 ASN A C 1 +ATOM 1671 O O . ASN A 1 229 ? 4.799 -27.680 7.920 1.00 117.74 ? 229 ASN A O 1 +ATOM 1672 C CB . ASN A 1 229 ? 6.494 -30.525 7.496 1.00 101.75 ? 229 ASN A CB 1 +ATOM 1673 C CG . ASN A 1 229 ? 5.212 -30.969 6.822 1.00 79.67 ? 229 ASN A CG 1 +ATOM 1674 O OD1 . ASN A 1 229 ? 4.693 -30.306 5.910 1.00 98.66 ? 229 ASN A OD1 1 +ATOM 1675 N ND2 . ASN A 1 229 ? 4.700 -32.114 7.258 1.00 67.85 ? 229 ASN A ND2 1 +ATOM 1676 N N . ASP A 1 230 ? 6.180 -28.196 9.625 1.00 55.86 ? 230 ASP A N 1 +ATOM 1677 C CA . ASP A 1 230 ? 5.368 -27.543 10.631 1.00 60.69 ? 230 ASP A CA 1 +ATOM 1678 C C . ASP A 1 230 ? 5.321 -26.053 10.347 1.00 52.63 ? 230 ASP A C 1 +ATOM 1679 O O . ASP A 1 230 ? 4.279 -25.418 10.489 1.00 50.84 ? 230 ASP A O 1 +ATOM 1680 C CB . ASP A 1 230 ? 5.952 -27.802 12.029 1.00 80.07 ? 230 ASP A CB 1 +ATOM 1681 C CG . ASP A 1 230 ? 5.097 -27.210 13.151 1.00 85.69 ? 230 ASP A CG 1 +ATOM 1682 O OD1 . ASP A 1 230 ? 4.033 -27.783 13.429 1.00 106.62 ? 230 ASP A OD1 1 +ATOM 1683 O OD2 . ASP A 1 230 ? 5.486 -26.202 13.759 1.00 90.22 ? 230 ASP A OD2 1 +ATOM 1684 N N . GLY A 1 231 ? 6.450 -25.515 9.938 1.00 44.65 ? 231 GLY A N 1 +ATOM 1685 C CA . GLY A 1 231 ? 6.535 -24.106 9.661 1.00 43.76 ? 231 GLY A CA 1 +ATOM 1686 C C . GLY A 1 231 ? 5.720 -23.766 8.440 1.00 51.97 ? 231 GLY A C 1 +ATOM 1687 O O . GLY A 1 231 ? 5.182 -22.657 8.327 1.00 64.68 ? 231 GLY A O 1 +ATOM 1688 N N . ILE A 1 232 ? 5.715 -24.672 7.464 1.00 71.10 ? 232 ILE A N 1 +ATOM 1689 C CA . ILE A 1 232 ? 4.908 -24.484 6.252 1.00 101.32 ? 232 ILE A CA 1 +ATOM 1690 C C . ILE A 1 232 ? 3.439 -24.343 6.651 1.00 109.85 ? 232 ILE A C 1 +ATOM 1691 O O . ILE A 1 232 ? 2.758 -23.422 6.204 1.00 87.81 ? 232 ILE A O 1 +ATOM 1692 C CB . ILE A 1 232 ? 5.095 -25.658 5.230 1.00 112.35 ? 232 ILE A CB 1 +ATOM 1693 C CG1 . ILE A 1 232 ? 6.462 -25.542 4.549 1.00 94.68 ? 232 ILE A CG1 1 +ATOM 1694 C CG2 . ILE A 1 232 ? 3.981 -25.681 4.174 1.00 128.72 ? 232 ILE A CG2 1 +ATOM 1695 C CD1 . ILE A 1 232 ? 6.922 -26.816 3.874 1.00 96.21 ? 232 ILE A CD1 1 +ATOM 1696 N N . ASP A 1 233 ? 2.954 -25.298 7.451 1.00 133.46 ? 233 ASP A N 1 +ATOM 1697 C CA . ASP A 1 233 ? 1.569 -25.299 7.942 1.00 103.90 ? 233 ASP A CA 1 +ATOM 1698 C C . ASP A 1 233 ? 1.253 -24.009 8.679 1.00 91.87 ? 233 ASP A C 1 +ATOM 1699 O O . ASP A 1 233 ? 0.244 -23.359 8.385 1.00 131.19 ? 233 ASP A O 1 +ATOM 1700 C CB . ASP A 1 233 ? 1.312 -26.481 8.886 1.00 94.91 ? 233 ASP A CB 1 +ATOM 1701 C CG . ASP A 1 233 ? 1.372 -27.837 8.182 1.00 106.32 ? 233 ASP A CG 1 +ATOM 1702 O OD1 . ASP A 1 233 ? 1.847 -27.896 6.996 1.00 125.95 ? 233 ASP A OD1 1 +ATOM 1703 O OD2 . ASP A 1 233 ? 1.038 -28.864 8.845 1.00 57.38 ? 233 ASP A OD2 1 +ATOM 1704 N N . ARG A 1 234 ? 2.121 -23.627 9.602 1.00 80.46 ? 234 ARG A N 1 +ATOM 1705 C CA . ARG A 1 234 ? 1.854 -22.474 10.455 1.00 86.28 ? 234 ARG A CA 1 +ATOM 1706 C C . ARG A 1 234 ? 2.121 -21.115 9.805 1.00 87.12 ? 234 ARG A C 1 +ATOM 1707 O O . ARG A 1 234 ? 1.934 -20.067 10.433 1.00 89.08 ? 234 ARG A O 1 +ATOM 1708 C CB . ARG A 1 234 ? 2.642 -22.609 11.755 1.00 78.20 ? 234 ARG A CB 1 +ATOM 1709 C CG . ARG A 1 234 ? 2.052 -23.678 12.636 1.00 87.80 ? 234 ARG A CG 1 +ATOM 1710 C CD . ARG A 1 234 ? 3.046 -24.204 13.645 1.00 101.90 ? 234 ARG A CD 1 +ATOM 1711 N NE . ARG A 1 234 ? 2.459 -25.316 14.406 1.00 126.15 ? 234 ARG A NE 1 +ATOM 1712 C CZ . ARG A 1 234 ? 2.341 -25.358 15.732 1.00 121.52 ? 234 ARG A CZ 1 +ATOM 1713 N NH1 . ARG A 1 234 ? 2.793 -24.344 16.464 1.00 159.20 ? 234 ARG A NH1 1 +ATOM 1714 N NH2 . ARG A 1 234 ? 1.768 -26.407 16.326 1.00 82.63 ? 234 ARG A NH2 1 +ATOM 1715 N N . GLY A 1 235 ? 2.588 -21.117 8.560 1.00 107.06 ? 235 GLY A N 1 +ATOM 1716 C CA . GLY A 1 235 ? 2.866 -19.861 7.850 1.00 119.36 ? 235 GLY A CA 1 +ATOM 1717 C C . GLY A 1 235 ? 4.114 -19.100 8.330 1.00 100.26 ? 235 GLY A C 1 +ATOM 1718 O O . GLY A 1 235 ? 4.148 -17.883 8.266 1.00 57.07 ? 235 GLY A O 1 +ATOM 1719 N N . LEU A 1 236 ? 5.150 -19.828 8.761 1.00 102.75 ? 236 LEU A N 1 +ATOM 1720 C CA . LEU A 1 236 ? 6.487 -19.237 8.956 1.00 65.71 ? 236 LEU A CA 1 +ATOM 1721 C C . LEU A 1 236 ? 7.170 -18.995 7.618 1.00 64.72 ? 236 LEU A C 1 +ATOM 1722 O O . LEU A 1 236 ? 7.585 -17.879 7.326 1.00 85.94 ? 236 LEU A O 1 +ATOM 1723 C CB . LEU A 1 236 ? 7.372 -20.149 9.774 1.00 83.15 ? 236 LEU A CB 1 +ATOM 1724 C CG . LEU A 1 236 ? 7.231 -20.115 11.301 1.00 123.65 ? 236 LEU A CG 1 +ATOM 1725 C CD1 . LEU A 1 236 ? 6.027 -20.935 11.748 1.00 171.06 ? 236 LEU A CD1 1 +ATOM 1726 C CD2 . LEU A 1 236 ? 8.490 -20.653 11.972 1.00 108.14 ? 236 LEU A CD2 1 +ATOM 1727 N N . TRP A 1 237 ? 7.170 -20.007 6.747 1.00 67.61 ? 237 TRP A N 1 +ATOM 1728 C CA . TRP A 1 237 ? 7.732 -19.893 5.377 1.00 75.88 ? 237 TRP A CA 1 +ATOM 1729 C C . TRP A 1 237 ? 6.876 -20.635 4.316 1.00 91.33 ? 237 TRP A C 1 +ATOM 1730 O O . TRP A 1 237 ? 5.897 -21.287 4.665 1.00 125.11 ? 237 TRP A O 1 +ATOM 1731 C CB . TRP A 1 237 ? 9.113 -20.487 5.375 1.00 65.91 ? 237 TRP A CB 1 +ATOM 1732 C CG . TRP A 1 237 ? 9.231 -21.631 6.277 1.00 72.46 ? 237 TRP A CG 1 +ATOM 1733 C CD1 . TRP A 1 237 ? 8.650 -22.846 6.117 1.00 92.57 ? 237 TRP A CD1 1 +ATOM 1734 C CD2 . TRP A 1 237 ? 10.001 -21.713 7.494 1.00 87.71 ? 237 TRP A CD2 1 +ATOM 1735 N NE1 . TRP A 1 237 ? 8.995 -23.678 7.159 1.00 114.06 ? 237 TRP A NE1 1 +ATOM 1736 C CE2 . TRP A 1 237 ? 9.819 -23.001 8.019 1.00 111.37 ? 237 TRP A CE2 1 +ATOM 1737 C CE3 . TRP A 1 237 ? 10.821 -20.823 8.191 1.00 102.83 ? 237 TRP A CE3 1 +ATOM 1738 C CZ2 . TRP A 1 237 ? 10.412 -23.416 9.232 1.00 127.17 ? 237 TRP A CZ2 1 +ATOM 1739 C CZ3 . TRP A 1 237 ? 11.399 -21.229 9.417 1.00 92.29 ? 237 TRP A CZ3 1 +ATOM 1740 C CH2 . TRP A 1 237 ? 11.193 -22.510 9.910 1.00 107.91 ? 237 TRP A CH2 1 +ATOM 1741 N N . ASP A 1 238 ? 7.127 -20.414 3.025 1.00 94.79 ? 238 ASP A N 1 +ATOM 1742 C CA . ASP A 1 238 ? 6.268 -21.020 1.965 1.00 103.34 ? 238 ASP A CA 1 +ATOM 1743 C C . ASP A 1 238 ? 7.044 -21.542 0.785 1.00 94.97 ? 238 ASP A C 1 +ATOM 1744 O O . ASP A 1 238 ? 8.151 -21.057 0.450 1.00 103.32 ? 238 ASP A O 1 +ATOM 1745 C CB . ASP A 1 238 ? 5.033 -20.113 1.516 1.00 129.95 ? 238 ASP A CB 1 +ATOM 1746 C CG . ASP A 1 238 ? 3.644 -20.762 1.921 1.00 134.70 ? 238 ASP A CG 1 +ATOM 1747 O OD1 . ASP A 1 238 ? 3.245 -21.840 1.375 1.00 118.81 ? 238 ASP A OD1 1 +ATOM 1748 O OD2 . ASP A 1 238 ? 3.046 -20.296 2.920 1.00 122.01 ? 238 ASP A OD2 1 +ATOM 1749 N N . LEU A 1 239 ? 6.357 -22.425 0.070 1.00 97.62 ? 239 LEU A N 1 +ATOM 1750 C CA . LEU A 1 239 ? 6.940 -23.143 -1.045 1.00 101.44 ? 239 LEU A CA 1 +ATOM 1751 C C . LEU A 1 239 ? 7.018 -22.318 -2.328 1.00 106.59 ? 239 LEU A C 1 +ATOM 1752 O O . LEU A 1 239 ? 6.121 -21.492 -2.619 1.00 140.65 ? 239 LEU A O 1 +ATOM 1753 C CB . LEU A 1 239 ? 6.130 -24.410 -1.332 1.00 88.03 ? 239 LEU A CB 1 +ATOM 1754 C CG . LEU A 1 239 ? 6.238 -25.585 -0.373 1.00 80.71 ? 239 LEU A CG 1 +ATOM 1755 C CD1 . LEU A 1 239 ? 5.473 -26.775 -0.916 1.00 55.13 ? 239 LEU A CD1 1 +ATOM 1756 C CD2 . LEU A 1 239 ? 7.690 -25.952 -0.166 1.00 102.25 ? 239 LEU A CD2 1 +ATOM 1757 N N . GLN A 1 240 ? 8.082 -22.558 -3.096 1.00 80.30 ? 240 GLN A N 1 +ATOM 1758 C CA . GLN A 1 240 ? 8.224 -21.970 -4.438 1.00 90.39 ? 240 GLN A CA 1 +ATOM 1759 C C . GLN A 1 240 ? 7.077 -22.375 -5.338 1.00 87.67 ? 240 GLN A C 1 +ATOM 1760 O O . GLN A 1 240 ? 6.326 -21.523 -5.832 1.00 106.69 ? 240 GLN A O 1 +ATOM 1761 C CB . GLN A 1 240 ? 9.525 -22.429 -5.086 1.00 105.04 ? 240 GLN A CB 1 +ATOM 1762 C CG . GLN A 1 240 ? 9.844 -21.746 -6.413 1.00 105.63 ? 240 GLN A CG 1 +ATOM 1763 C CD . GLN A 1 240 ? 10.111 -20.254 -6.244 1.00 120.53 ? 240 GLN A CD 1 +ATOM 1764 O OE1 . GLN A 1 240 ? 11.208 -19.851 -5.852 1.00 138.73 ? 240 GLN A OE1 1 +ATOM 1765 N NE2 . GLN A 1 240 ? 9.091 -19.431 -6.488 1.00 107.89 ? 240 GLN A NE2 1 +ATOM 1766 N N . ASN A 1 241 ? 6.873 -23.683 -5.450 1.00 103.29 ? 241 ASN A N 1 +ATOM 1767 C CA . ASN A 1 241 ? 5.745 -24.256 -6.205 1.00 133.68 ? 241 ASN A CA 1 +ATOM 1768 C C . ASN A 1 241 ? 4.614 -24.768 -5.318 1.00 142.28 ? 241 ASN A C 1 +ATOM 1769 O O . ASN A 1 241 ? 4.793 -25.719 -4.539 1.00 163.21 ? 241 ASN A O 1 +ATOM 1770 C CB . ASN A 1 241 ? 6.235 -25.426 -7.027 1.00 147.99 ? 241 ASN A CB 1 +ATOM 1771 C CG . ASN A 1 241 ? 6.477 -25.065 -8.464 1.00 194.35 ? 241 ASN A CG 1 +ATOM 1772 O OD1 . ASN A 1 241 ? 5.653 -25.362 -9.321 1.00 201.05 ? 241 ASN A OD1 1 +ATOM 1773 N ND2 . ASN A 1 241 ? 7.587 -24.373 -8.733 1.00 236.27 ? 241 ASN A ND2 1 +ATOM 1774 N N . LYS A 1 242 ? 3.465 -24.090 -5.390 1.00 129.93 ? 242 LYS A N 1 +ATOM 1775 C CA . LYS A 1 242 ? 2.333 -24.402 -4.520 1.00 112.32 ? 242 LYS A CA 1 +ATOM 1776 C C . LYS A 1 242 ? 1.794 -25.746 -4.972 1.00 85.84 ? 242 LYS A C 1 +ATOM 1777 O O . LYS A 1 242 ? 1.215 -26.483 -4.142 1.00 102.98 ? 242 LYS A O 1 +ATOM 1778 C CB . LYS A 1 242 ? 1.256 -23.316 -4.617 1.00 119.15 ? 242 LYS A CB 1 +ATOM 1779 C CG . LYS A 1 242 ? 1.776 -21.899 -4.390 1.00 151.82 ? 242 LYS A CG 1 +ATOM 1780 C CD . LYS A 1 242 ? 1.017 -21.157 -3.314 1.00 184.60 ? 242 LYS A CD 1 +ATOM 1781 C CE . LYS A 1 242 ? 1.962 -20.465 -2.339 1.00 219.38 ? 242 LYS A CE 1 +ATOM 1782 N NZ . LYS A 1 242 ? 1.234 -19.573 -1.394 1.00 242.90 ? 242 LYS A NZ 1 +ATOM 1783 N N . ALA A 1 243 ? 2.084 -26.092 -6.224 1.00 59.37 ? 243 ALA A N 1 +ATOM 1784 C CA . ALA A 1 243 ? 1.784 -27.407 -6.790 1.00 61.84 ? 243 ALA A CA 1 +ATOM 1785 C C . ALA A 1 243 ? 2.567 -28.529 -6.117 1.00 82.80 ? 243 ALA A C 1 +ATOM 1786 O O . ALA A 1 243 ? 2.143 -29.692 -6.152 1.00 131.78 ? 243 ALA A O 1 +ATOM 1787 C CB . ALA A 1 243 ? 2.099 -27.422 -8.259 1.00 49.38 ? 243 ALA A CB 1 +ATOM 1788 N N . GLU A 1 244 ? 3.636 -28.183 -5.412 1.00 88.79 ? 244 GLU A N 1 +ATOM 1789 C CA . GLU A 1 244 ? 4.432 -29.193 -4.737 1.00 84.79 ? 244 GLU A CA 1 +ATOM 1790 C C . GLU A 1 244 ? 4.015 -29.490 -3.294 1.00 75.01 ? 244 GLU A C 1 +ATOM 1791 O O . GLU A 1 244 ? 4.788 -30.078 -2.538 1.00 96.65 ? 244 GLU A O 1 +ATOM 1792 C CB . GLU A 1 244 ? 5.915 -28.797 -4.813 1.00 110.44 ? 244 GLU A CB 1 +ATOM 1793 C CG . GLU A 1 244 ? 6.513 -28.943 -6.213 1.00 116.07 ? 244 GLU A CG 1 +ATOM 1794 C CD . GLU A 1 244 ? 8.025 -28.807 -6.254 1.00 116.91 ? 244 GLU A CD 1 +ATOM 1795 O OE1 . GLU A 1 244 ? 8.538 -27.676 -6.127 1.00 131.33 ? 244 GLU A OE1 1 +ATOM 1796 O OE2 . GLU A 1 244 ? 8.705 -29.848 -6.327 1.00 128.90 ? 244 GLU A OE2 1 +ATOM 1797 N N . ARG A 1 245 ? 2.871 -28.951 -2.876 1.00 67.76 ? 245 ARG A N 1 +ATOM 1798 C CA . ARG A 1 245 ? 2.306 -29.150 -1.537 1.00 77.22 ? 245 ARG A CA 1 +ATOM 1799 C C . ARG A 1 245 ? 2.156 -30.660 -1.248 1.00 72.07 ? 245 ARG A C 1 +ATOM 1800 O O . ARG A 1 245 ? 2.459 -31.156 -0.109 1.00 109.53 ? 245 ARG A O 1 +ATOM 1801 C CB . ARG A 1 245 ? 0.899 -28.375 -1.475 1.00 90.58 ? 245 ARG A CB 1 +ATOM 1802 C CG . ARG A 1 245 ? 1.000 -26.858 -1.248 1.00 107.73 ? 245 ARG A CG 1 +ATOM 1803 C CD . ARG A 1 245 ? -0.232 -26.090 -1.567 1.00 102.09 ? 245 ARG A CD 1 +ATOM 1804 N NE . ARG A 1 245 ? -0.169 -24.718 -1.132 1.00 139.32 ? 245 ARG A NE 1 +ATOM 1805 C CZ . ARG A 1 245 ? -1.201 -23.884 -1.184 1.00 140.35 ? 245 ARG A CZ 1 +ATOM 1806 N NH1 . ARG A 1 245 ? -2.417 -24.305 -1.520 1.00 156.70 ? 245 ARG A NH1 1 +ATOM 1807 N NH2 . ARG A 1 245 ? -1.021 -22.628 -0.828 1.00 172.01 ? 245 ARG A NH2 1 +ATOM 1808 N N . GLN A 1 246 ? 1.766 -31.407 -2.275 1.00 60.69 ? 246 GLN A N 1 +ATOM 1809 C CA . GLN A 1 246 ? 1.493 -32.824 -2.092 1.00 73.63 ? 246 GLN A CA 1 +ATOM 1810 C C . GLN A 1 246 ? 2.702 -33.680 -2.487 1.00 74.50 ? 246 GLN A C 1 +ATOM 1811 O O . GLN A 1 246 ? 2.573 -34.888 -2.708 1.00 55.20 ? 246 GLN A O 1 +ATOM 1812 C CB . GLN A 1 246 ? 0.282 -33.259 -2.911 1.00 79.89 ? 246 GLN A CB 1 +ATOM 1813 C CG . GLN A 1 246 ? -1.055 -32.740 -2.412 1.00 78.14 ? 246 GLN A CG 1 +ATOM 1814 C CD . GLN A 1 246 ? -1.284 -31.297 -2.766 1.00 94.67 ? 246 GLN A CD 1 +ATOM 1815 O OE1 . GLN A 1 246 ? -0.979 -30.863 -3.868 1.00 114.09 ? 246 GLN A OE1 1 +ATOM 1816 N NE2 . GLN A 1 246 ? -1.769 -30.525 -1.803 1.00 127.02 ? 246 GLN A NE2 1 +ATOM 1817 N N . ASN A 1 247 ? 3.883 -33.081 -2.426 1.00 86.87 ? 247 ASN A N 1 +ATOM 1818 C CA . ASN A 1 247 ? 5.151 -33.811 -2.451 1.00 101.75 ? 247 ASN A CA 1 +ATOM 1819 C C . ASN A 1 247 ? 5.128 -35.090 -1.613 1.00 93.49 ? 247 ASN A C 1 +ATOM 1820 O O . ASN A 1 247 ? 4.630 -35.088 -0.471 1.00 108.34 ? 247 ASN A O 1 +ATOM 1821 C CB . ASN A 1 247 ? 6.270 -32.893 -1.925 1.00 115.50 ? 247 ASN A CB 1 +ATOM 1822 C CG . ASN A 1 247 ? 7.624 -33.225 -2.499 1.00 107.43 ? 247 ASN A CG 1 +ATOM 1823 O OD1 . ASN A 1 247 ? 8.478 -33.776 -1.812 1.00 82.50 ? 247 ASN A OD1 1 +ATOM 1824 N ND2 . ASN A 1 247 ? 7.809 -32.936 -3.780 1.00 100.73 ? 247 ASN A ND2 1 +ATOM 1825 N N . ASP A 1 248 ? 5.693 -36.167 -2.161 1.00 89.62 ? 248 ASP A N 1 +ATOM 1826 C CA . ASP A 1 248 ? 5.684 -37.481 -1.492 1.00 109.98 ? 248 ASP A CA 1 +ATOM 1827 C C . ASP A 1 248 ? 6.230 -37.375 -0.066 1.00 105.02 ? 248 ASP A C 1 +ATOM 1828 O O . ASP A 1 248 ? 5.668 -37.942 0.890 1.00 114.60 ? 248 ASP A O 1 +ATOM 1829 C CB . ASP A 1 248 ? 6.533 -38.496 -2.276 1.00 107.11 ? 248 ASP A CB 1 +ATOM 1830 C CG . ASP A 1 248 ? 5.892 -38.914 -3.579 1.00 115.93 ? 248 ASP A CG 1 +ATOM 1831 O OD1 . ASP A 1 248 ? 4.650 -39.082 -3.625 1.00 145.43 ? 248 ASP A OD1 1 +ATOM 1832 O OD2 . ASP A 1 248 ? 6.631 -39.110 -4.559 1.00 112.90 ? 248 ASP A OD2 1 +ATOM 1833 N N . ILE A 1 249 ? 7.346 -36.669 0.061 1.00 91.34 ? 249 ILE A N 1 +ATOM 1834 C CA . ILE A 1 249 ? 8.056 -36.571 1.324 1.00 95.96 ? 249 ILE A CA 1 +ATOM 1835 C C . ILE A 1 249 ? 7.216 -35.776 2.320 1.00 77.08 ? 249 ILE A C 1 +ATOM 1836 O O . ILE A 1 249 ? 6.997 -36.212 3.453 1.00 82.76 ? 249 ILE A O 1 +ATOM 1837 C CB . ILE A 1 249 ? 9.440 -35.915 1.118 1.00 100.99 ? 249 ILE A CB 1 +ATOM 1838 C CG1 . ILE A 1 249 ? 10.316 -36.789 0.206 1.00 121.84 ? 249 ILE A CG1 1 +ATOM 1839 C CG2 . ILE A 1 249 ? 10.141 -35.720 2.447 1.00 87.81 ? 249 ILE A CG2 1 +ATOM 1840 C CD1 . ILE A 1 249 ? 11.461 -36.048 -0.456 1.00 123.39 ? 249 ILE A CD1 1 +ATOM 1841 N N . LEU A 1 250 ? 6.732 -34.625 1.874 1.00 72.39 ? 250 LEU A N 1 +ATOM 1842 C CA . LEU A 1 250 ? 5.955 -33.727 2.730 1.00 70.84 ? 250 LEU A CA 1 +ATOM 1843 C C . LEU A 1 250 ? 4.682 -34.375 3.271 1.00 75.26 ? 250 LEU A C 1 +ATOM 1844 O O . LEU A 1 250 ? 4.317 -34.155 4.430 1.00 83.60 ? 250 LEU A O 1 +ATOM 1845 C CB . LEU A 1 250 ? 5.596 -32.446 1.979 1.00 60.07 ? 250 LEU A CB 1 +ATOM 1846 C CG . LEU A 1 250 ? 6.711 -31.412 1.912 1.00 60.33 ? 250 LEU A CG 1 +ATOM 1847 C CD1 . LEU A 1 250 ? 6.404 -30.296 0.919 1.00 57.25 ? 250 LEU A CD1 1 +ATOM 1848 C CD2 . LEU A 1 250 ? 6.969 -30.822 3.291 1.00 73.83 ? 250 LEU A CD2 1 +ATOM 1849 N N . VAL A 1 251 ? 4.039 -35.195 2.447 1.00 73.70 ? 251 VAL A N 1 +ATOM 1850 C CA . VAL A 1 251 ? 2.822 -35.894 2.867 1.00 82.96 ? 251 VAL A CA 1 +ATOM 1851 C C . VAL A 1 251 ? 3.151 -37.100 3.743 1.00 88.37 ? 251 VAL A C 1 +ATOM 1852 O O . VAL A 1 251 ? 2.328 -37.534 4.558 1.00 119.90 ? 251 VAL A O 1 +ATOM 1853 C CB . VAL A 1 251 ? 1.947 -36.344 1.661 1.00 87.33 ? 251 VAL A CB 1 +ATOM 1854 C CG1 . VAL A 1 251 ? 1.623 -35.150 0.752 1.00 107.80 ? 251 VAL A CG1 1 +ATOM 1855 C CG2 . VAL A 1 251 ? 2.609 -37.463 0.872 1.00 74.58 ? 251 VAL A CG2 1 +ATOM 1856 N N . LYS A 1 252 ? 4.359 -37.632 3.587 1.00 86.02 ? 252 LYS A N 1 +ATOM 1857 C CA . LYS A 1 252 ? 4.826 -38.743 4.425 1.00 74.33 ? 252 LYS A CA 1 +ATOM 1858 C C . LYS A 1 252 ? 5.054 -38.283 5.873 1.00 68.39 ? 252 LYS A C 1 +ATOM 1859 O O . LYS A 1 252 ? 4.570 -38.905 6.823 1.00 82.48 ? 252 LYS A O 1 +ATOM 1860 C CB . LYS A 1 252 ? 6.105 -39.311 3.831 1.00 82.47 ? 252 LYS A CB 1 +ATOM 1861 C CG . LYS A 1 252 ? 6.728 -40.451 4.606 1.00 99.12 ? 252 LYS A CG 1 +ATOM 1862 C CD . LYS A 1 252 ? 8.028 -40.902 3.942 1.00 111.05 ? 252 LYS A CD 1 +ATOM 1863 C CE . LYS A 1 252 ? 9.158 -41.050 4.954 1.00 125.00 ? 252 LYS A CE 1 +ATOM 1864 N NZ . LYS A 1 252 ? 10.484 -41.234 4.308 1.00 123.25 ? 252 LYS A NZ 1 +ATOM 1865 N N . TYR A 1 253 ? 5.709 -37.138 6.032 1.00 71.75 ? 253 TYR A N 1 +ATOM 1866 C CA . TYR A 1 253 ? 5.969 -36.568 7.366 1.00 80.23 ? 253 TYR A CA 1 +ATOM 1867 C C . TYR A 1 253 ? 4.692 -35.974 7.952 1.00 73.25 ? 253 TYR A C 1 +ATOM 1868 O O . TYR A 1 253 ? 4.517 -35.912 9.163 1.00 53.53 ? 253 TYR A O 1 +ATOM 1869 C CB . TYR A 1 253 ? 7.122 -35.524 7.331 1.00 87.56 ? 253 TYR A CB 1 +ATOM 1870 C CG . TYR A 1 253 ? 8.471 -36.170 7.187 1.00 91.88 ? 253 TYR A CG 1 +ATOM 1871 C CD1 . TYR A 1 253 ? 8.930 -36.497 5.920 1.00 126.45 ? 253 TYR A CD1 1 +ATOM 1872 C CD2 . TYR A 1 253 ? 9.244 -36.544 8.289 1.00 69.25 ? 253 TYR A CD2 1 +ATOM 1873 C CE1 . TYR A 1 253 ? 10.119 -37.176 5.725 1.00 133.53 ? 253 TYR A CE1 1 +ATOM 1874 C CE2 . TYR A 1 253 ? 10.452 -37.201 8.094 1.00 84.15 ? 253 TYR A CE2 1 +ATOM 1875 C CZ . TYR A 1 253 ? 10.874 -37.538 6.814 1.00 109.87 ? 253 TYR A CZ 1 +ATOM 1876 O OH . TYR A 1 253 ? 12.002 -38.326 6.586 1.00 110.71 ? 253 TYR A OH 1 +ATOM 1877 N N . ARG A 1 254 ? 3.853 -35.430 7.074 1.00 91.76 ? 254 ARG A N 1 +ATOM 1878 C CA . ARG A 1 254 ? 2.536 -34.943 7.485 1.00 91.44 ? 254 ARG A CA 1 +ATOM 1879 C C . ARG A 1 254 ? 1.798 -36.098 8.128 1.00 70.14 ? 254 ARG A C 1 +ATOM 1880 O O . ARG A 1 254 ? 1.049 -35.887 9.082 1.00 79.52 ? 254 ARG A O 1 +ATOM 1881 C CB . ARG A 1 254 ? 1.732 -34.353 6.281 1.00 92.53 ? 254 ARG A CB 1 +ATOM 1882 C CG . ARG A 1 254 ? 0.234 -34.109 6.625 1.00 73.91 ? 254 ARG A CG 1 +ATOM 1883 C CD . ARG A 1 254 ? 0.025 -33.020 7.726 1.00 66.50 ? 254 ARG A CD 1 +ATOM 1884 N NE . ARG A 1 254 ? 1.112 -32.035 7.745 1.00 67.06 ? 254 ARG A NE 1 +ATOM 1885 C CZ . ARG A 1 254 ? 1.130 -30.962 6.998 1.00 70.59 ? 254 ARG A CZ 1 +ATOM 1886 N NH1 . ARG A 1 254 ? 0.042 -30.619 6.351 1.00 92.21 ? 254 ARG A NH1 1 +ATOM 1887 N NH2 . ARG A 1 254 ? 2.210 -30.201 6.932 1.00 111.81 ? 254 ARG A NH2 1 +ATOM 1888 N N . HIS A 1 255 ? 1.917 -37.268 7.504 1.00 70.27 ? 255 HIS A N 1 +ATOM 1889 C CA . HIS A 1 255 ? 1.208 -38.467 7.943 1.00 81.27 ? 255 HIS A CA 1 +ATOM 1890 C C . HIS A 1 255 ? 1.741 -38.982 9.269 1.00 74.11 ? 255 HIS A C 1 +ATOM 1891 O O . HIS A 1 255 ? 0.970 -39.470 10.093 1.00 83.07 ? 255 HIS A O 1 +ATOM 1892 C CB . HIS A 1 255 ? 1.256 -39.571 6.880 1.00 94.26 ? 255 HIS A CB 1 +ATOM 1893 C CG . HIS A 1 255 ? -0.057 -39.800 6.184 1.00 123.07 ? 255 HIS A CG 1 +ATOM 1894 N ND1 . HIS A 1 255 ? -1.019 -40.647 6.692 1.00 155.42 ? 255 HIS A ND1 1 +ATOM 1895 C CD2 . HIS A 1 255 ? -0.601 -39.243 5.072 1.00 144.74 ? 255 HIS A CD2 1 +ATOM 1896 C CE1 . HIS A 1 255 ? -2.095 -40.609 5.928 1.00 174.77 ? 255 HIS A CE1 1 +ATOM 1897 N NE2 . HIS A 1 255 ? -1.863 -39.776 4.929 1.00 182.64 ? 255 HIS A NE2 1 +ATOM 1898 N N . MET A 1 256 ? 3.026 -38.775 9.526 1.00 88.12 ? 256 MET A N 1 +ATOM 1899 C CA . MET A 1 256 ? 3.613 -39.207 10.805 1.00 91.38 ? 256 MET A CA 1 +ATOM 1900 C C . MET A 1 256 ? 3.189 -38.317 11.981 1.00 70.60 ? 256 MET A C 1 +ATOM 1901 O O . MET A 1 256 ? 3.053 -38.791 13.118 1.00 67.85 ? 256 MET A O 1 +ATOM 1902 C CB . MET A 1 256 ? 5.138 -39.239 10.729 1.00 97.29 ? 256 MET A CB 1 +ATOM 1903 C CG . MET A 1 256 ? 5.690 -40.045 9.566 1.00 101.35 ? 256 MET A CG 1 +ATOM 1904 S SD . MET A 1 256 ? 7.416 -40.535 9.727 1.00 97.62 ? 256 MET A SD 1 +ATOM 1905 C CE . MET A 1 256 ? 7.275 -41.760 11.050 1.00 98.59 ? 256 MET A CE 1 +ATOM 1906 N N . SER A 1 257 ? 2.843 -37.072 11.703 1.00 61.60 ? 257 SER A N 1 +ATOM 1907 C CA . SER A 1 257 ? 2.296 -36.216 12.758 1.00 68.83 ? 257 SER A CA 1 +ATOM 1908 C C . SER A 1 257 ? 0.926 -36.722 13.250 1.00 79.00 ? 257 SER A C 1 +ATOM 1909 O O . SER A 1 257 ? 0.736 -37.176 14.381 1.00 81.28 ? 257 SER A O 1 +ATOM 1910 C CB . SER A 1 257 ? 2.167 -34.790 12.211 1.00 78.22 ? 257 SER A CB 1 +ATOM 1911 O OG . SER A 1 257 ? 3.324 -34.418 11.527 1.00 103.82 ? 257 SER A OG 1 +ATOM 1912 N N . LEU B 1 2 ? 32.405 -55.517 3.173 1.00 154.04 ? 2 LEU B N 1 +ATOM 1913 C CA . LEU B 1 2 ? 31.788 -55.656 4.534 1.00 157.26 ? 2 LEU B CA 1 +ATOM 1914 C C . LEU B 1 2 ? 32.852 -55.434 5.644 1.00 148.08 ? 2 LEU B C 1 +ATOM 1915 O O . LEU B 1 2 ? 33.271 -56.380 6.365 1.00 63.56 ? 2 LEU B O 1 +ATOM 1916 C CB . LEU B 1 2 ? 31.075 -57.013 4.685 1.00 159.45 ? 2 LEU B CB 1 +ATOM 1917 C CG . LEU B 1 2 ? 29.891 -57.353 3.744 1.00 120.03 ? 2 LEU B CG 1 +ATOM 1918 C CD1 . LEU B 1 2 ? 29.376 -58.758 4.066 1.00 105.71 ? 2 LEU B CD1 1 +ATOM 1919 C CD2 . LEU B 1 2 ? 28.741 -56.342 3.772 1.00 98.78 ? 2 LEU B CD2 1 +ATOM 1920 N N . THR B 1 3 ? 33.354 -54.192 5.650 1.00 160.57 ? 3 THR B N 1 +ATOM 1921 C CA . THR B 1 3 ? 34.095 -53.589 6.758 1.00 153.94 ? 3 THR B CA 1 +ATOM 1922 C C . THR B 1 3 ? 33.727 -52.093 6.924 1.00 155.62 ? 3 THR B C 1 +ATOM 1923 O O . THR B 1 3 ? 34.219 -51.419 7.833 1.00 150.07 ? 3 THR B O 1 +ATOM 1924 C CB . THR B 1 3 ? 35.625 -53.675 6.549 1.00 129.37 ? 3 THR B CB 1 +ATOM 1925 O OG1 . THR B 1 3 ? 36.013 -52.819 5.455 1.00 98.55 ? 3 THR B OG1 1 +ATOM 1926 C CG2 . THR B 1 3 ? 36.074 -55.123 6.301 1.00 124.27 ? 3 THR B CG2 1 +ATOM 1927 N N . ALA B 1 4 ? 32.932 -51.563 5.998 1.00 137.77 ? 4 ALA B N 1 +ATOM 1928 C CA . ALA B 1 4 ? 32.331 -50.233 6.156 1.00 125.95 ? 4 ALA B CA 1 +ATOM 1929 C C . ALA B 1 4 ? 31.135 -50.318 7.138 1.00 113.39 ? 4 ALA B C 1 +ATOM 1930 O O . ALA B 1 4 ? 30.902 -51.373 7.728 1.00 94.26 ? 4 ALA B O 1 +ATOM 1931 C CB . ALA B 1 4 ? 31.935 -49.673 4.783 1.00 117.92 ? 4 ALA B CB 1 +ATOM 1932 N N . PRO B 1 5 ? 30.409 -49.203 7.376 1.00 112.25 ? 5 PRO B N 1 +ATOM 1933 C CA . PRO B 1 5 ? 29.477 -49.344 8.489 1.00 103.59 ? 5 PRO B CA 1 +ATOM 1934 C C . PRO B 1 5 ? 28.198 -50.155 8.165 1.00 118.85 ? 5 PRO B C 1 +ATOM 1935 O O . PRO B 1 5 ? 27.935 -50.483 6.994 1.00 141.70 ? 5 PRO B O 1 +ATOM 1936 C CB . PRO B 1 5 ? 29.123 -47.896 8.819 1.00 101.50 ? 5 PRO B CB 1 +ATOM 1937 C CG . PRO B 1 5 ? 29.268 -47.150 7.524 1.00 112.40 ? 5 PRO B CG 1 +ATOM 1938 C CD . PRO B 1 5 ? 30.164 -47.956 6.615 1.00 118.00 ? 5 PRO B CD 1 +ATOM 1939 N N . PRO B 1 6 ? 27.418 -50.513 9.206 1.00 104.15 ? 6 PRO B N 1 +ATOM 1940 C CA . PRO B 1 6 ? 26.063 -51.071 9.028 1.00 100.11 ? 6 PRO B CA 1 +ATOM 1941 C C . PRO B 1 6 ? 25.017 -50.001 8.716 1.00 95.95 ? 6 PRO B C 1 +ATOM 1942 O O . PRO B 1 6 ? 25.209 -48.847 9.102 1.00 91.50 ? 6 PRO B O 1 +ATOM 1943 C CB . PRO B 1 6 ? 25.767 -51.750 10.377 1.00 87.87 ? 6 PRO B CB 1 +ATOM 1944 C CG . PRO B 1 6 ? 26.747 -51.220 11.348 1.00 75.45 ? 6 PRO B CG 1 +ATOM 1945 C CD . PRO B 1 6 ? 27.894 -50.601 10.597 1.00 91.98 ? 6 PRO B CD 1 +ATOM 1946 N N . LYS B 1 7 ? 23.941 -50.380 8.020 1.00 91.00 ? 7 LYS B N 1 +ATOM 1947 C CA . LYS B 1 7 ? 22.917 -49.411 7.608 1.00 111.80 ? 7 LYS B CA 1 +ATOM 1948 C C . LYS B 1 7 ? 21.737 -49.396 8.565 1.00 91.97 ? 7 LYS B C 1 +ATOM 1949 O O . LYS B 1 7 ? 21.657 -50.262 9.455 1.00 84.73 ? 7 LYS B O 1 +ATOM 1950 C CB . LYS B 1 7 ? 22.418 -49.685 6.191 1.00 124.62 ? 7 LYS B CB 1 +ATOM 1951 C CG . LYS B 1 7 ? 23.434 -49.421 5.104 1.00 148.10 ? 7 LYS B CG 1 +ATOM 1952 C CD . LYS B 1 7 ? 24.036 -50.697 4.522 1.00 134.70 ? 7 LYS B CD 1 +ATOM 1953 C CE . LYS B 1 7 ? 24.794 -50.394 3.239 1.00 153.26 ? 7 LYS B CE 1 +ATOM 1954 N NZ . LYS B 1 7 ? 25.918 -51.343 3.011 1.00 152.35 ? 7 LYS B NZ 1 +ATOM 1955 N N . GLU B 1 8 ? 20.880 -48.378 8.418 1.00 73.07 ? 8 GLU B N 1 +ATOM 1956 C CA . GLU B 1 8 ? 19.922 -48.028 9.467 1.00 77.59 ? 8 GLU B CA 1 +ATOM 1957 C C . GLU B 1 8 ? 18.871 -49.112 9.664 1.00 76.20 ? 8 GLU B C 1 +ATOM 1958 O O . GLU B 1 8 ? 18.129 -49.444 8.750 1.00 64.54 ? 8 GLU B O 1 +ATOM 1959 C CB . GLU B 1 8 ? 19.250 -46.649 9.215 1.00 102.02 ? 8 GLU B CB 1 +ATOM 1960 C CG . GLU B 1 8 ? 18.093 -46.568 8.240 1.00 133.63 ? 8 GLU B CG 1 +ATOM 1961 C CD . GLU B 1 8 ? 17.377 -45.208 8.278 1.00 153.44 ? 8 GLU B CD 1 +ATOM 1962 O OE1 . GLU B 1 8 ? 16.919 -44.767 9.357 1.00 146.56 ? 8 GLU B OE1 1 +ATOM 1963 O OE2 . GLU B 1 8 ? 17.200 -44.593 7.217 1.00 176.46 ? 8 GLU B OE2 1 +ATOM 1964 N N . ALA B 1 9 ? 18.809 -49.643 10.879 1.00 73.56 ? 9 ALA B N 1 +ATOM 1965 C CA . ALA B 1 9 ? 17.776 -50.584 11.263 1.00 71.11 ? 9 ALA B CA 1 +ATOM 1966 C C . ALA B 1 9 ? 16.682 -49.832 12.013 1.00 70.74 ? 9 ALA B C 1 +ATOM 1967 O O . ALA B 1 9 ? 16.897 -49.359 13.128 1.00 59.47 ? 9 ALA B O 1 +ATOM 1968 C CB . ALA B 1 9 ? 18.372 -51.674 12.140 1.00 73.58 ? 9 ALA B CB 1 +ATOM 1969 N N . ALA B 1 10 ? 15.500 -49.769 11.391 1.00 65.41 ? 10 ALA B N 1 +ATOM 1970 C CA . ALA B 1 10 ? 14.342 -48.982 11.857 1.00 61.76 ? 10 ALA B CA 1 +ATOM 1971 C C . ALA B 1 10 ? 14.474 -47.565 11.365 1.00 70.55 ? 10 ALA B C 1 +ATOM 1972 O O . ALA B 1 10 ? 15.569 -47.109 11.030 1.00 62.78 ? 10 ALA B O 1 +ATOM 1973 C CB . ALA B 1 10 ? 14.166 -49.027 13.379 1.00 58.17 ? 10 ALA B CB 1 +ATOM 1974 N N . ARG B 1 11 ? 13.349 -46.867 11.319 1.00 93.33 ? 11 ARG B N 1 +ATOM 1975 C CA . ARG B 1 11 ? 13.316 -45.477 10.845 1.00 108.84 ? 11 ARG B CA 1 +ATOM 1976 C C . ARG B 1 11 ? 13.243 -44.523 12.037 1.00 94.96 ? 11 ARG B C 1 +ATOM 1977 O O . ARG B 1 11 ? 12.698 -44.878 13.070 1.00 103.02 ? 11 ARG B O 1 +ATOM 1978 C CB . ARG B 1 11 ? 12.089 -45.248 9.943 1.00 141.38 ? 11 ARG B CB 1 +ATOM 1979 C CG . ARG B 1 11 ? 10.741 -45.367 10.650 1.00 166.52 ? 11 ARG B CG 1 +ATOM 1980 C CD . ARG B 1 11 ? 9.637 -45.779 9.678 1.00 174.40 ? 11 ARG B CD 1 +ATOM 1981 N NE . ARG B 1 11 ? 9.158 -47.138 9.926 1.00 178.38 ? 11 ARG B NE 1 +ATOM 1982 C CZ . ARG B 1 11 ? 8.191 -47.726 9.227 1.00 154.06 ? 11 ARG B CZ 1 +ATOM 1983 N NH1 . ARG B 1 11 ? 7.571 -47.061 8.260 1.00 134.11 ? 11 ARG B NH1 1 +ATOM 1984 N NH2 . ARG B 1 11 ? 7.834 -48.976 9.501 1.00 145.31 ? 11 ARG B NH2 1 +ATOM 1985 N N . PRO B 1 12 ? 13.750 -43.290 11.882 1.00 92.06 ? 12 PRO B N 1 +ATOM 1986 C CA . PRO B 1 12 ? 13.389 -42.276 12.861 1.00 91.08 ? 12 PRO B CA 1 +ATOM 1987 C C . PRO B 1 12 ? 11.888 -41.974 12.818 1.00 96.12 ? 12 PRO B C 1 +ATOM 1988 O O . PRO B 1 12 ? 11.375 -41.480 11.818 1.00 82.91 ? 12 PRO B O 1 +ATOM 1989 C CB . PRO B 1 12 ? 14.207 -41.050 12.427 1.00 93.66 ? 12 PRO B CB 1 +ATOM 1990 C CG . PRO B 1 12 ? 15.197 -41.541 11.420 1.00 95.17 ? 12 PRO B CG 1 +ATOM 1991 C CD . PRO B 1 12 ? 14.560 -42.731 10.785 1.00 100.97 ? 12 PRO B CD 1 +ATOM 1992 N N . THR B 1 13 ? 11.191 -42.324 13.892 1.00 101.86 ? 13 THR B N 1 +ATOM 1993 C CA . THR B 1 13 ? 9.823 -41.877 14.117 1.00 98.68 ? 13 THR B CA 1 +ATOM 1994 C C . THR B 1 13 ? 9.789 -40.644 15.015 1.00 87.89 ? 13 THR B C 1 +ATOM 1995 O O . THR B 1 13 ? 10.772 -40.352 15.709 1.00 104.65 ? 13 THR B O 1 +ATOM 1996 C CB . THR B 1 13 ? 9.021 -42.978 14.805 1.00 108.95 ? 13 THR B CB 1 +ATOM 1997 O OG1 . THR B 1 13 ? 7.636 -42.627 14.801 1.00 179.54 ? 13 THR B OG1 1 +ATOM 1998 C CG2 . THR B 1 13 ? 9.523 -43.238 16.263 1.00 102.45 ? 13 THR B CG2 1 +ATOM 1999 N N . LEU B 1 14 ? 8.690 -39.899 15.015 1.00 72.40 ? 14 LEU B N 1 +ATOM 2000 C CA . LEU B 1 14 ? 8.590 -38.847 16.020 1.00 83.20 ? 14 LEU B CA 1 +ATOM 2001 C C . LEU B 1 14 ? 8.317 -39.531 17.349 1.00 76.61 ? 14 LEU B C 1 +ATOM 2002 O O . LEU B 1 14 ? 7.841 -40.658 17.373 1.00 68.39 ? 14 LEU B O 1 +ATOM 2003 C CB . LEU B 1 14 ? 7.606 -37.718 15.647 1.00 77.38 ? 14 LEU B CB 1 +ATOM 2004 C CG . LEU B 1 14 ? 6.220 -38.092 15.204 1.00 92.75 ? 14 LEU B CG 1 +ATOM 2005 C CD1 . LEU B 1 14 ? 5.209 -37.036 15.632 1.00 113.50 ? 14 LEU B CD1 1 +ATOM 2006 C CD2 . LEU B 1 14 ? 6.206 -38.231 13.699 1.00 106.25 ? 14 LEU B CD2 1 +ATOM 2007 N N . MET B 1 15 ? 8.679 -38.881 18.450 1.00 82.88 ? 15 MET B N 1 +ATOM 2008 C CA . MET B 1 15 ? 8.604 -39.507 19.769 1.00 98.07 ? 15 MET B CA 1 +ATOM 2009 C C . MET B 1 15 ? 7.334 -40.232 20.211 1.00 95.66 ? 15 MET B C 1 +ATOM 2010 O O . MET B 1 15 ? 6.263 -39.628 20.279 1.00 130.27 ? 15 MET B O 1 +ATOM 2011 C CB . MET B 1 15 ? 8.730 -38.451 20.870 1.00 114.03 ? 15 MET B CB 1 +ATOM 2012 C CG . MET B 1 15 ? 9.484 -38.925 22.102 1.00 120.04 ? 15 MET B CG 1 +ATOM 2013 S SD . MET B 1 15 ? 9.183 -37.886 23.544 1.00 128.68 ? 15 MET B SD 1 +ATOM 2014 C CE . MET B 1 15 ? 8.284 -39.021 24.598 1.00 90.31 ? 15 MET B CE 1 +ATOM 2015 N N . PRO B 1 16 ? 7.452 -41.523 20.517 1.00 88.52 ? 16 PRO B N 1 +ATOM 2016 C CA . PRO B 1 16 ? 6.262 -42.340 20.807 1.00 88.42 ? 16 PRO B CA 1 +ATOM 2017 C C . PRO B 1 16 ? 5.595 -42.037 22.146 1.00 91.46 ? 16 PRO B C 1 +ATOM 2018 O O . PRO B 1 16 ? 5.858 -42.703 23.165 1.00 127.74 ? 16 PRO B O 1 +ATOM 2019 C CB . PRO B 1 16 ? 6.821 -43.765 20.809 1.00 123.27 ? 16 PRO B CB 1 +ATOM 2020 C CG . PRO B 1 16 ? 8.285 -43.612 21.094 1.00 130.18 ? 16 PRO B CG 1 +ATOM 2021 C CD . PRO B 1 16 ? 8.665 -42.351 20.399 1.00 116.59 ? 16 PRO B CD 1 +ATOM 2022 N N . ARG B 1 17 ? 4.755 -41.014 22.158 1.00 84.59 ? 17 ARG B N 1 +ATOM 2023 C CA . ARG B 1 17 ? 3.976 -40.653 23.355 1.00 78.51 ? 17 ARG B CA 1 +ATOM 2024 C C . ARG B 1 17 ? 2.686 -41.415 23.331 1.00 76.60 ? 17 ARG B C 1 +ATOM 2025 O O . ARG B 1 17 ? 2.159 -41.680 22.247 1.00 74.10 ? 17 ARG B O 1 +ATOM 2026 C CB . ARG B 1 17 ? 3.693 -39.150 23.373 1.00 77.58 ? 17 ARG B CB 1 +ATOM 2027 C CG . ARG B 1 17 ? 4.795 -38.351 24.055 1.00 118.39 ? 17 ARG B CG 1 +ATOM 2028 C CD . ARG B 1 17 ? 4.777 -36.862 23.727 1.00 111.27 ? 17 ARG B CD 1 +ATOM 2029 N NE . ARG B 1 17 ? 5.327 -36.589 22.393 1.00 140.31 ? 17 ARG B NE 1 +ATOM 2030 C CZ . ARG B 1 17 ? 5.315 -35.398 21.805 1.00 154.33 ? 17 ARG B CZ 1 +ATOM 2031 N NH1 . ARG B 1 17 ? 4.788 -34.369 22.461 1.00 183.91 ? 17 ARG B NH1 1 +ATOM 2032 N NH2 . ARG B 1 17 ? 5.826 -35.234 20.575 1.00 119.62 ? 17 ARG B NH2 1 +ATOM 2033 N N . ALA B 1 18 ? 2.156 -41.789 24.497 1.00 83.30 ? 18 ALA B N 1 +ATOM 2034 C CA . ALA B 1 18 ? 0.916 -42.597 24.548 1.00 105.39 ? 18 ALA B CA 1 +ATOM 2035 C C . ALA B 1 18 ? -0.299 -41.849 25.136 1.00 101.44 ? 18 ALA B C 1 +ATOM 2036 O O . ALA B 1 18 ? -0.761 -40.854 24.548 1.00 130.41 ? 18 ALA B O 1 +ATOM 2037 C CB . ALA B 1 18 ? 1.147 -43.918 25.274 1.00 99.10 ? 18 ALA B CB 1 +ATOM 2038 N N . GLN B 1 19 ? -0.861 -42.367 26.226 1.00 86.91 ? 19 GLN B N 1 +ATOM 2039 C CA . GLN B 1 19 ? -2.232 -42.021 26.608 1.00 116.58 ? 19 GLN B CA 1 +ATOM 2040 C C . GLN B 1 19 ? -2.319 -40.582 27.111 1.00 116.34 ? 19 GLN B C 1 +ATOM 2041 O O . GLN B 1 19 ? -3.199 -39.800 26.708 1.00 124.72 ? 19 GLN B O 1 +ATOM 2042 C CB . GLN B 1 19 ? -2.739 -42.985 27.688 1.00 130.40 ? 19 GLN B CB 1 +ATOM 2043 C CG . GLN B 1 19 ? -4.205 -42.790 28.074 1.00 141.76 ? 19 GLN B CG 1 +ATOM 2044 C CD . GLN B 1 19 ? -5.149 -42.850 26.884 1.00 148.72 ? 19 GLN B CD 1 +ATOM 2045 O OE1 . GLN B 1 19 ? -5.301 -43.894 26.249 1.00 177.95 ? 19 GLN B OE1 1 +ATOM 2046 N NE2 . GLN B 1 19 ? -5.766 -41.718 26.558 1.00 160.00 ? 19 GLN B NE2 1 +ATOM 2047 N N . SER B 1 20 ? -1.429 -40.269 28.041 1.00 106.95 ? 20 SER B N 1 +ATOM 2048 C CA . SER B 1 20 ? -1.262 -38.922 28.551 1.00 112.39 ? 20 SER B CA 1 +ATOM 2049 C C . SER B 1 20 ? -1.316 -37.889 27.421 1.00 107.70 ? 20 SER B C 1 +ATOM 2050 O O . SER B 1 20 ? -2.064 -36.910 27.498 1.00 98.87 ? 20 SER B O 1 +ATOM 2051 C CB . SER B 1 20 ? 0.082 -38.841 29.286 1.00 128.38 ? 20 SER B CB 1 +ATOM 2052 O OG . SER B 1 20 ? 0.210 -39.900 30.229 1.00 158.94 ? 20 SER B OG 1 +ATOM 2053 N N . TYR B 1 21 ? -0.532 -38.128 26.368 1.00 112.23 ? 21 TYR B N 1 +ATOM 2054 C CA . TYR B 1 21 ? -0.511 -37.265 25.179 1.00 112.95 ? 21 TYR B CA 1 +ATOM 2055 C C . TYR B 1 21 ? -1.890 -37.102 24.535 1.00 130.87 ? 21 TYR B C 1 +ATOM 2056 O O . TYR B 1 21 ? -2.328 -35.975 24.249 1.00 131.92 ? 21 TYR B O 1 +ATOM 2057 C CB . TYR B 1 21 ? 0.464 -37.824 24.137 1.00 108.74 ? 21 TYR B CB 1 +ATOM 2058 C CG . TYR B 1 21 ? 0.580 -36.967 22.900 1.00 93.13 ? 21 TYR B CG 1 +ATOM 2059 C CD1 . TYR B 1 21 ? 1.289 -35.772 22.923 1.00 93.56 ? 21 TYR B CD1 1 +ATOM 2060 C CD2 . TYR B 1 21 ? -0.034 -37.337 21.715 1.00 88.93 ? 21 TYR B CD2 1 +ATOM 2061 C CE1 . TYR B 1 21 ? 1.381 -34.966 21.808 1.00 80.03 ? 21 TYR B CE1 1 +ATOM 2062 C CE2 . TYR B 1 21 ? 0.088 -36.555 20.585 1.00 80.70 ? 21 TYR B CE2 1 +ATOM 2063 C CZ . TYR B 1 21 ? 0.793 -35.374 20.645 1.00 68.28 ? 21 TYR B CZ 1 +ATOM 2064 O OH . TYR B 1 21 ? 0.912 -34.568 19.546 1.00 77.02 ? 21 TYR B OH 1 +ATOM 2065 N N . LYS B 1 22 ? -2.567 -38.226 24.303 1.00 119.07 ? 22 LYS B N 1 +ATOM 2066 C CA . LYS B 1 22 ? -3.874 -38.218 23.652 1.00 105.89 ? 22 LYS B CA 1 +ATOM 2067 C C . LYS B 1 22 ? -4.916 -37.415 24.439 1.00 102.32 ? 22 LYS B C 1 +ATOM 2068 O O . LYS B 1 22 ? -5.712 -36.677 23.860 1.00 105.06 ? 22 LYS B O 1 +ATOM 2069 C CB . LYS B 1 22 ? -4.370 -39.643 23.472 1.00 110.18 ? 22 LYS B CB 1 +ATOM 2070 C CG . LYS B 1 22 ? -3.918 -40.279 22.179 1.00 145.54 ? 22 LYS B CG 1 +ATOM 2071 C CD . LYS B 1 22 ? -4.831 -39.847 21.025 1.00 175.52 ? 22 LYS B CD 1 +ATOM 2072 C CE . LYS B 1 22 ? -5.828 -40.966 20.686 1.00 195.87 ? 22 LYS B CE 1 +ATOM 2073 N NZ . LYS B 1 22 ? -5.139 -42.172 20.156 1.00 184.63 ? 22 LYS B NZ 1 +ATOM 2074 N N . ASP B 1 23 ? -4.896 -37.561 25.761 1.00 91.41 ? 23 ASP B N 1 +ATOM 2075 C CA . ASP B 1 23 ? -5.729 -36.749 26.645 1.00 83.32 ? 23 ASP B CA 1 +ATOM 2076 C C . ASP B 1 23 ? -5.358 -35.271 26.540 1.00 80.12 ? 23 ASP B C 1 +ATOM 2077 O O . ASP B 1 23 ? -6.221 -34.400 26.469 1.00 87.15 ? 23 ASP B O 1 +ATOM 2078 C CB . ASP B 1 23 ? -5.572 -37.218 28.102 1.00 88.12 ? 23 ASP B CB 1 +ATOM 2079 C CG . ASP B 1 23 ? -6.150 -38.582 28.334 1.00 105.31 ? 23 ASP B CG 1 +ATOM 2080 O OD1 . ASP B 1 23 ? -7.224 -38.864 27.755 1.00 116.99 ? 23 ASP B OD1 1 +ATOM 2081 O OD2 . ASP B 1 23 ? -5.504 -39.391 29.038 1.00 119.60 ? 23 ASP B OD2 1 +ATOM 2082 N N . LEU B 1 24 ? -4.056 -35.003 26.585 1.00 96.33 ? 24 LEU B N 1 +ATOM 2083 C CA . LEU B 1 24 ? -3.525 -33.640 26.653 1.00 99.70 ? 24 LEU B CA 1 +ATOM 2084 C C . LEU B 1 24 ? -3.871 -32.840 25.393 1.00 100.75 ? 24 LEU B C 1 +ATOM 2085 O O . LEU B 1 24 ? -4.107 -31.614 25.462 1.00 63.49 ? 24 LEU B O 1 +ATOM 2086 C CB . LEU B 1 24 ? -1.999 -33.688 26.851 1.00 99.92 ? 24 LEU B CB 1 +ATOM 2087 C CG . LEU B 1 24 ? -1.247 -32.352 26.948 1.00 96.42 ? 24 LEU B CG 1 +ATOM 2088 C CD1 . LEU B 1 24 ? -1.241 -31.823 28.374 1.00 85.09 ? 24 LEU B CD1 1 +ATOM 2089 C CD2 . LEU B 1 24 ? 0.179 -32.527 26.443 1.00 118.29 ? 24 LEU B CD2 1 +ATOM 2090 N N . THR B 1 25 ? -3.880 -33.533 24.250 1.00 92.99 ? 25 THR B N 1 +ATOM 2091 C CA . THR B 1 25 ? -4.115 -32.881 22.971 1.00 118.09 ? 25 THR B CA 1 +ATOM 2092 C C . THR B 1 25 ? -5.597 -32.562 22.775 1.00 115.11 ? 25 THR B C 1 +ATOM 2093 O O . THR B 1 25 ? -5.954 -31.434 22.383 1.00 134.28 ? 25 THR B O 1 +ATOM 2094 C CB . THR B 1 25 ? -3.617 -33.745 21.794 1.00 125.12 ? 25 THR B CB 1 +ATOM 2095 O OG1 . THR B 1 25 ? -4.038 -35.097 21.976 1.00 135.64 ? 25 THR B OG1 1 +ATOM 2096 C CG2 . THR B 1 25 ? -2.099 -33.694 21.704 1.00 121.48 ? 25 THR B CG2 1 +ATOM 2097 N N . HIS B 1 26 ? -6.446 -33.545 23.062 1.00 98.89 ? 26 HIS B N 1 +ATOM 2098 C CA . HIS B 1 26 ? -7.887 -33.416 22.865 1.00 96.36 ? 26 HIS B CA 1 +ATOM 2099 C C . HIS B 1 26 ? -8.556 -32.725 24.079 1.00 107.57 ? 26 HIS B C 1 +ATOM 2100 O O . HIS B 1 26 ? -9.676 -33.050 24.450 1.00 119.30 ? 26 HIS B O 1 +ATOM 2101 C CB . HIS B 1 26 ? -8.511 -34.799 22.588 1.00 89.93 ? 26 HIS B CB 1 +ATOM 2102 C CG . HIS B 1 26 ? -8.028 -35.441 21.315 1.00 105.20 ? 26 HIS B CG 1 +ATOM 2103 N ND1 . HIS B 1 26 ? -6.739 -35.902 21.151 1.00 127.32 ? 26 HIS B ND1 1 +ATOM 2104 C CD2 . HIS B 1 26 ? -8.658 -35.685 20.141 1.00 120.44 ? 26 HIS B CD2 1 +ATOM 2105 C CE1 . HIS B 1 26 ? -6.591 -36.386 19.930 1.00 105.59 ? 26 HIS B CE1 1 +ATOM 2106 N NE2 . HIS B 1 26 ? -7.741 -36.267 19.296 1.00 106.60 ? 26 HIS B NE2 1 +ATOM 2107 N N . LEU B 1 27 ? -7.879 -31.743 24.675 1.00 115.42 ? 27 LEU B N 1 +ATOM 2108 C CA . LEU B 1 27 ? -8.469 -30.940 25.753 1.00 99.32 ? 27 LEU B CA 1 +ATOM 2109 C C . LEU B 1 27 ? -9.204 -29.736 25.177 1.00 106.31 ? 27 LEU B C 1 +ATOM 2110 O O . LEU B 1 27 ? -8.698 -29.069 24.274 1.00 116.16 ? 27 LEU B O 1 +ATOM 2111 C CB . LEU B 1 27 ? -7.391 -30.454 26.722 1.00 102.54 ? 27 LEU B CB 1 +ATOM 2112 C CG . LEU B 1 27 ? -7.051 -31.424 27.856 1.00 121.76 ? 27 LEU B CG 1 +ATOM 2113 C CD1 . LEU B 1 27 ? -5.773 -31.007 28.562 1.00 132.68 ? 27 LEU B CD1 1 +ATOM 2114 C CD2 . LEU B 1 27 ? -8.192 -31.526 28.852 1.00 119.36 ? 27 LEU B CD2 1 +ATOM 2115 N N . PRO B 1 28 ? -10.412 -29.453 25.690 1.00 110.77 ? 28 PRO B N 1 +ATOM 2116 C CA . PRO B 1 28 ? -11.233 -28.333 25.199 1.00 109.82 ? 28 PRO B CA 1 +ATOM 2117 C C . PRO B 1 28 ? -10.528 -27.011 25.390 1.00 98.32 ? 28 PRO B C 1 +ATOM 2118 O O . PRO B 1 28 ? -10.036 -26.740 26.465 1.00 107.29 ? 28 PRO B O 1 +ATOM 2119 C CB . PRO B 1 28 ? -12.479 -28.387 26.090 1.00 111.92 ? 28 PRO B CB 1 +ATOM 2120 C CG . PRO B 1 28 ? -12.046 -29.121 27.315 1.00 108.56 ? 28 PRO B CG 1 +ATOM 2121 C CD . PRO B 1 28 ? -11.038 -30.127 26.839 1.00 115.49 ? 28 PRO B CD 1 +ATOM 2122 N N . ALA B 1 29 ? -10.456 -26.207 24.343 1.00 97.68 ? 29 ALA B N 1 +ATOM 2123 C CA . ALA B 1 29 ? -9.575 -25.049 24.346 1.00 94.65 ? 29 ALA B CA 1 +ATOM 2124 C C . ALA B 1 29 ? -10.110 -23.933 25.276 1.00 87.43 ? 29 ALA B C 1 +ATOM 2125 O O . ALA B 1 29 ? -11.316 -23.741 25.403 1.00 72.71 ? 29 ALA B O 1 +ATOM 2126 C CB . ALA B 1 29 ? -9.346 -24.548 22.906 1.00 98.52 ? 29 ALA B CB 1 +ATOM 2127 N N . PRO B 1 30 ? -9.200 -23.171 25.903 1.00 90.60 ? 30 PRO B N 1 +ATOM 2128 C CA . PRO B 1 30 ? -9.545 -21.965 26.653 1.00 93.11 ? 30 PRO B CA 1 +ATOM 2129 C C . PRO B 1 30 ? -9.948 -20.749 25.781 1.00 79.15 ? 30 PRO B C 1 +ATOM 2130 O O . PRO B 1 30 ? -9.811 -20.801 24.556 1.00 59.69 ? 30 PRO B O 1 +ATOM 2131 C CB . PRO B 1 30 ? -8.240 -21.647 27.377 1.00 105.65 ? 30 PRO B CB 1 +ATOM 2132 C CG . PRO B 1 30 ? -7.175 -22.109 26.450 1.00 107.54 ? 30 PRO B CG 1 +ATOM 2133 C CD . PRO B 1 30 ? -7.742 -23.292 25.712 1.00 105.58 ? 30 PRO B CD 1 +ATOM 2134 N N . THR B 1 31 ? -10.366 -19.652 26.426 1.00 77.23 ? 31 THR B N 1 +ATOM 2135 C CA . THR B 1 31 ? -10.776 -18.423 25.715 1.00 93.44 ? 31 THR B CA 1 +ATOM 2136 C C . THR B 1 31 ? -9.619 -17.714 25.008 1.00 85.60 ? 31 THR B C 1 +ATOM 2137 O O . THR B 1 31 ? -9.813 -17.041 24.007 1.00 60.13 ? 31 THR B O 1 +ATOM 2138 C CB . THR B 1 31 ? -11.482 -17.395 26.643 1.00 116.96 ? 31 THR B CB 1 +ATOM 2139 O OG1 . THR B 1 31 ? -10.673 -17.101 27.789 1.00 95.05 ? 31 THR B OG1 1 +ATOM 2140 C CG2 . THR B 1 31 ? -12.836 -17.917 27.099 1.00 138.64 ? 31 THR B CG2 1 +ATOM 2141 N N . GLY B 1 32 ? -8.411 -17.892 25.528 1.00 112.18 ? 32 GLY B N 1 +ATOM 2142 C CA . GLY B 1 32 ? -7.188 -17.548 24.804 1.00 121.33 ? 32 GLY B CA 1 +ATOM 2143 C C . GLY B 1 32 ? -6.057 -18.407 25.346 1.00 121.43 ? 32 GLY B C 1 +ATOM 2144 O O . GLY B 1 32 ? -6.113 -18.836 26.488 1.00 107.60 ? 32 GLY B O 1 +ATOM 2145 N N . LYS B 1 33 ? -5.024 -18.653 24.539 1.00 121.53 ? 33 LYS B N 1 +ATOM 2146 C CA . LYS B 1 33 ? -3.827 -19.399 24.985 1.00 107.95 ? 33 LYS B CA 1 +ATOM 2147 C C . LYS B 1 33 ? -3.014 -18.502 26.039 1.00 93.89 ? 33 LYS B C 1 +ATOM 2148 O O . LYS B 1 33 ? -3.138 -17.252 26.062 1.00 93.28 ? 33 LYS B O 1 +ATOM 2149 C CB . LYS B 1 33 ? -3.058 -19.948 23.705 1.00 105.74 ? 33 LYS B CB 1 +ATOM 2150 C CG . LYS B 1 33 ? -3.869 -19.756 22.413 1.00 124.06 ? 33 LYS B CG 1 +ATOM 2151 C CD . LYS B 1 33 ? -2.988 -19.700 21.182 1.00 123.03 ? 33 LYS B CD 1 +ATOM 2152 C CE . LYS B 1 33 ? -3.616 -18.828 20.110 1.00 98.06 ? 33 LYS B CE 1 +ATOM 2153 N NZ . LYS B 1 33 ? -2.673 -18.608 18.975 1.00 109.41 ? 33 LYS B NZ 1 +ATOM 2154 N N . ILE B 1 34 ? -2.437 -19.137 27.061 1.00 84.64 ? 34 ILE B N 1 +ATOM 2155 C CA . ILE B 1 34 ? -1.808 -18.422 28.178 1.00 95.05 ? 34 ILE B CA 1 +ATOM 2156 C C . ILE B 1 34 ? -0.281 -18.458 27.973 1.00 113.58 ? 34 ILE B C 1 +ATOM 2157 O O . ILE B 1 34 ? 0.246 -19.410 27.389 1.00 137.78 ? 34 ILE B O 1 +ATOM 2158 C CB . ILE B 1 34 ? -2.257 -19.001 29.552 1.00 106.40 ? 34 ILE B CB 1 +ATOM 2159 C CG1 . ILE B 1 34 ? -3.746 -18.720 29.791 1.00 120.22 ? 34 ILE B CG1 1 +ATOM 2160 C CG2 . ILE B 1 34 ? -1.489 -18.385 30.723 1.00 124.13 ? 34 ILE B CG2 1 +ATOM 2161 C CD1 . ILE B 1 34 ? -4.587 -19.969 29.916 1.00 134.09 ? 34 ILE B CD1 1 +ATOM 2162 N N . PHE B 1 35 ? 0.383 -17.350 28.308 1.00 97.61 ? 35 PHE B N 1 +ATOM 2163 C CA . PHE B 1 35 ? 1.816 -17.196 28.140 1.00 97.15 ? 35 PHE B CA 1 +ATOM 2164 C C . PHE B 1 35 ? 2.553 -17.798 29.323 1.00 110.42 ? 35 PHE B C 1 +ATOM 2165 O O . PHE B 1 35 ? 2.296 -17.399 30.462 1.00 157.12 ? 35 PHE B O 1 +ATOM 2166 C CB . PHE B 1 35 ? 2.159 -15.710 28.100 1.00 119.68 ? 35 PHE B CB 1 +ATOM 2167 C CG . PHE B 1 35 ? 2.052 -15.086 26.736 1.00 110.93 ? 35 PHE B CG 1 +ATOM 2168 C CD1 . PHE B 1 35 ? 2.571 -15.718 25.618 1.00 99.19 ? 35 PHE B CD1 1 +ATOM 2169 C CD2 . PHE B 1 35 ? 1.556 -13.800 26.607 1.00 121.75 ? 35 PHE B CD2 1 +ATOM 2170 C CE1 . PHE B 1 35 ? 2.522 -15.109 24.385 1.00 110.00 ? 35 PHE B CE1 1 +ATOM 2171 C CE2 . PHE B 1 35 ? 1.533 -13.174 25.381 1.00 116.67 ? 35 PHE B CE2 1 +ATOM 2172 C CZ . PHE B 1 35 ? 2.007 -13.835 24.266 1.00 118.61 ? 35 PHE B CZ 1 +ATOM 2173 N N . VAL B 1 36 ? 3.501 -18.698 29.065 1.00 85.53 ? 36 VAL B N 1 +ATOM 2174 C CA . VAL B 1 36 ? 4.149 -19.394 30.150 1.00 61.85 ? 36 VAL B CA 1 +ATOM 2175 C C . VAL B 1 36 ? 5.633 -19.444 30.000 1.00 63.73 ? 36 VAL B C 1 +ATOM 2176 O O . VAL B 1 36 ? 6.174 -19.433 28.904 1.00 79.68 ? 36 VAL B O 1 +ATOM 2177 C CB . VAL B 1 36 ? 3.623 -20.818 30.261 1.00 68.34 ? 36 VAL B CB 1 +ATOM 2178 C CG1 . VAL B 1 36 ? 4.182 -21.701 29.157 1.00 72.17 ? 36 VAL B CG1 1 +ATOM 2179 C CG2 . VAL B 1 36 ? 3.950 -21.391 31.623 1.00 71.58 ? 36 VAL B CG2 1 +ATOM 2180 N N . SER B 1 37 ? 6.313 -19.532 31.126 1.00 80.48 ? 37 SER B N 1 +ATOM 2181 C CA . SER B 1 37 ? 7.770 -19.576 31.140 1.00 83.19 ? 37 SER B CA 1 +ATOM 2182 C C . SER B 1 37 ? 8.176 -20.833 31.857 1.00 69.67 ? 37 SER B C 1 +ATOM 2183 O O . SER B 1 37 ? 7.771 -21.043 32.982 1.00 90.59 ? 37 SER B O 1 +ATOM 2184 C CB . SER B 1 37 ? 8.353 -18.351 31.880 1.00 69.69 ? 37 SER B CB 1 +ATOM 2185 O OG . SER B 1 37 ? 8.248 -17.169 31.096 1.00 56.09 ? 37 SER B OG 1 +ATOM 2186 N N . VAL B 1 38 ? 9.103 -21.585 31.284 1.00 82.16 ? 38 VAL B N 1 +ATOM 2187 C CA . VAL B 1 38 ? 9.818 -22.608 32.068 1.00 80.64 ? 38 VAL B CA 1 +ATOM 2188 C C . VAL B 1 38 ? 11.338 -22.378 32.075 1.00 76.10 ? 38 VAL B C 1 +ATOM 2189 O O . VAL B 1 38 ? 11.950 -22.338 30.993 1.00 98.23 ? 38 VAL B O 1 +ATOM 2190 C CB . VAL B 1 38 ? 9.572 -24.006 31.502 1.00 69.05 ? 38 VAL B CB 1 +ATOM 2191 C CG1 . VAL B 1 38 ? 10.340 -25.008 32.319 1.00 61.91 ? 38 VAL B CG1 1 +ATOM 2192 C CG2 . VAL B 1 38 ? 8.093 -24.339 31.474 1.00 64.92 ? 38 VAL B CG2 1 +ATOM 2193 N N . TYR B 1 39 ? 11.920 -22.191 33.270 1.00 69.93 ? 39 TYR B N 1 +ATOM 2194 C CA . TYR B 1 39 ? 13.361 -21.848 33.434 1.00 67.25 ? 39 TYR B CA 1 +ATOM 2195 C C . TYR B 1 39 ? 14.161 -23.128 33.627 1.00 65.82 ? 39 TYR B C 1 +ATOM 2196 O O . TYR B 1 39 ? 15.047 -23.432 32.831 1.00 102.64 ? 39 TYR B O 1 +ATOM 2197 C CB . TYR B 1 39 ? 13.597 -20.879 34.600 1.00 53.83 ? 39 TYR B CB 1 +ATOM 2198 C CG . TYR B 1 39 ? 13.443 -19.426 34.222 1.00 66.59 ? 39 TYR B CG 1 +ATOM 2199 C CD1 . TYR B 1 39 ? 12.174 -18.849 34.019 1.00 71.26 ? 39 TYR B CD1 1 +ATOM 2200 C CD2 . TYR B 1 39 ? 14.559 -18.625 34.012 1.00 93.09 ? 39 TYR B CD2 1 +ATOM 2201 C CE1 . TYR B 1 39 ? 12.042 -17.518 33.664 1.00 79.99 ? 39 TYR B CE1 1 +ATOM 2202 C CE2 . TYR B 1 39 ? 14.448 -17.275 33.669 1.00 108.19 ? 39 TYR B CE2 1 +ATOM 2203 C CZ . TYR B 1 39 ? 13.189 -16.721 33.509 1.00 109.28 ? 39 TYR B CZ 1 +ATOM 2204 O OH . TYR B 1 39 ? 13.087 -15.408 33.070 1.00 96.03 ? 39 TYR B OH 1 +ATOM 2205 N N . ASN B 1 40 ? 13.706 -23.982 34.524 1.00 59.51 ? 40 ASN B N 1 +ATOM 2206 C CA . ASN B 1 40 ? 14.377 -25.248 34.736 1.00 60.68 ? 40 ASN B CA 1 +ATOM 2207 C C . ASN B 1 40 ? 13.613 -26.223 35.645 1.00 66.25 ? 40 ASN B C 1 +ATOM 2208 O O . ASN B 1 40 ? 13.121 -25.852 36.719 1.00 66.77 ? 40 ASN B O 1 +ATOM 2209 C CB . ASN B 1 40 ? 15.728 -24.978 35.356 1.00 72.23 ? 40 ASN B CB 1 +ATOM 2210 C CG . ASN B 1 40 ? 16.668 -26.152 35.206 1.00 113.40 ? 40 ASN B CG 1 +ATOM 2211 O OD1 . ASN B 1 40 ? 16.990 -26.592 34.098 1.00 167.82 ? 40 ASN B OD1 1 +ATOM 2212 N ND2 . ASN B 1 40 ? 17.163 -26.634 36.329 1.00 154.03 ? 40 ASN B ND2 1 +ATOM 2213 N N . ILE B 1 41 ? 13.543 -27.477 35.232 1.00 82.37 ? 41 ILE B N 1 +ATOM 2214 C CA . ILE B 1 41 ? 13.063 -28.556 36.101 1.00 99.19 ? 41 ILE B CA 1 +ATOM 2215 C C . ILE B 1 41 ? 14.203 -29.559 36.336 1.00 115.38 ? 41 ILE B C 1 +ATOM 2216 O O . ILE B 1 41 ? 14.701 -30.185 35.394 1.00 163.59 ? 41 ILE B O 1 +ATOM 2217 C CB . ILE B 1 41 ? 11.850 -29.299 35.483 1.00 86.19 ? 41 ILE B CB 1 +ATOM 2218 C CG1 . ILE B 1 41 ? 10.556 -28.530 35.713 1.00 67.36 ? 41 ILE B CG1 1 +ATOM 2219 C CG2 . ILE B 1 41 ? 11.681 -30.648 36.151 1.00 89.13 ? 41 ILE B CG2 1 +ATOM 2220 C CD1 . ILE B 1 41 ? 10.426 -27.257 34.924 1.00 72.26 ? 41 ILE B CD1 1 +ATOM 2221 N N . GLN B 1 42 ? 14.634 -29.696 37.583 1.00 94.36 ? 42 GLN B N 1 +ATOM 2222 C CA . GLN B 1 42 ? 15.871 -30.423 37.886 1.00 94.80 ? 42 GLN B CA 1 +ATOM 2223 C C . GLN B 1 42 ? 15.631 -31.895 38.109 1.00 79.56 ? 42 GLN B C 1 +ATOM 2224 O O . GLN B 1 42 ? 14.556 -32.293 38.527 1.00 84.78 ? 42 GLN B O 1 +ATOM 2225 C CB . GLN B 1 42 ? 16.561 -29.845 39.129 1.00 126.60 ? 42 GLN B CB 1 +ATOM 2226 C CG . GLN B 1 42 ? 17.073 -28.415 38.981 1.00 166.94 ? 42 GLN B CG 1 +ATOM 2227 C CD . GLN B 1 42 ? 16.406 -27.455 39.976 1.00 179.15 ? 42 GLN B CD 1 +ATOM 2228 O OE1 . GLN B 1 42 ? 16.917 -27.239 41.062 1.00 164.19 ? 42 GLN B OE1 1 +ATOM 2229 N NE2 . GLN B 1 42 ? 15.239 -26.923 39.614 1.00 181.74 ? 42 GLN B NE2 1 +ATOM 2230 N N . ASP B 1 43 ? 16.686 -32.675 37.922 1.00 73.75 ? 43 ASP B N 1 +ATOM 2231 C CA . ASP B 1 43 ? 16.735 -34.049 38.367 1.00 81.35 ? 43 ASP B CA 1 +ATOM 2232 C C . ASP B 1 43 ? 17.040 -34.112 39.866 1.00 90.07 ? 43 ASP B C 1 +ATOM 2233 O O . ASP B 1 43 ? 18.079 -34.644 40.273 1.00 86.77 ? 43 ASP B O 1 +ATOM 2234 C CB . ASP B 1 43 ? 17.815 -34.814 37.595 1.00 98.41 ? 43 ASP B CB 1 +ATOM 2235 C CG . ASP B 1 43 ? 17.749 -36.332 37.826 1.00 112.48 ? 43 ASP B CG 1 +ATOM 2236 O OD1 . ASP B 1 43 ? 16.651 -36.909 37.693 1.00 89.55 ? 43 ASP B OD1 1 +ATOM 2237 O OD2 . ASP B 1 43 ? 18.795 -36.967 38.111 1.00 127.13 ? 43 ASP B OD2 1 +ATOM 2238 N N . GLU B 1 44 ? 16.101 -33.632 40.690 1.00 116.54 ? 44 GLU B N 1 +ATOM 2239 C CA . GLU B 1 44 ? 16.247 -33.621 42.165 1.00 132.13 ? 44 GLU B CA 1 +ATOM 2240 C C . GLU B 1 44 ? 16.151 -35.049 42.783 1.00 104.39 ? 44 GLU B C 1 +ATOM 2241 O O . GLU B 1 44 ? 16.074 -35.203 44.015 1.00 92.42 ? 44 GLU B O 1 +ATOM 2242 C CB . GLU B 1 44 ? 15.189 -32.699 42.820 1.00 142.49 ? 44 GLU B CB 1 +ATOM 2243 C CG . GLU B 1 44 ? 15.571 -31.215 42.924 1.00 120.12 ? 44 GLU B CG 1 +ATOM 2244 C CD . GLU B 1 44 ? 14.472 -30.321 43.545 1.00 130.60 ? 44 GLU B CD 1 +ATOM 2245 O OE1 . GLU B 1 44 ? 13.847 -30.691 44.575 1.00 152.36 ? 44 GLU B OE1 1 +ATOM 2246 O OE2 . GLU B 1 44 ? 14.216 -29.222 43.005 1.00 94.75 ? 44 GLU B OE2 1 +ATOM 2247 N N . THR B 1 45 ? 16.278 -36.066 41.925 1.00 80.70 ? 45 THR B N 1 +ATOM 2248 C CA . THR B 1 45 ? 16.114 -37.454 42.323 1.00 69.01 ? 45 THR B CA 1 +ATOM 2249 C C . THR B 1 45 ? 17.258 -37.992 43.181 1.00 75.65 ? 45 THR B C 1 +ATOM 2250 O O . THR B 1 45 ? 17.016 -38.739 44.127 1.00 90.80 ? 45 THR B O 1 +ATOM 2251 C CB . THR B 1 45 ? 15.814 -38.386 41.106 1.00 58.88 ? 45 THR B CB 1 +ATOM 2252 O OG1 . THR B 1 45 ? 15.320 -39.628 41.584 1.00 67.95 ? 45 THR B OG1 1 +ATOM 2253 C CG2 . THR B 1 45 ? 17.020 -38.655 40.246 1.00 53.55 ? 45 THR B CG2 1 +ATOM 2254 N N . GLY B 1 46 ? 18.499 -37.666 42.827 1.00 94.45 ? 46 GLY B N 1 +ATOM 2255 C CA . GLY B 1 46 ? 19.671 -38.058 43.627 1.00 103.19 ? 46 GLY B CA 1 +ATOM 2256 C C . GLY B 1 46 ? 20.246 -39.433 43.271 1.00 117.31 ? 46 GLY B C 1 +ATOM 2257 O O . GLY B 1 46 ? 20.960 -40.090 44.049 1.00 81.68 ? 46 GLY B O 1 +ATOM 2258 N N . GLN B 1 47 ? 19.925 -39.902 42.086 1.00 105.72 ? 47 GLN B N 1 +ATOM 2259 C CA . GLN B 1 47 ? 20.048 -41.288 41.861 1.00 80.07 ? 47 GLN B CA 1 +ATOM 2260 C C . GLN B 1 47 ? 20.798 -41.553 40.582 1.00 72.81 ? 47 GLN B C 1 +ATOM 2261 O O . GLN B 1 47 ? 20.579 -40.932 39.546 1.00 54.46 ? 47 GLN B O 1 +ATOM 2262 C CB . GLN B 1 47 ? 18.681 -41.925 41.874 1.00 69.55 ? 47 GLN B CB 1 +ATOM 2263 C CG . GLN B 1 47 ? 18.050 -41.922 43.247 1.00 88.14 ? 47 GLN B CG 1 +ATOM 2264 C CD . GLN B 1 47 ? 18.975 -42.452 44.320 1.00 124.16 ? 47 GLN B CD 1 +ATOM 2265 O OE1 . GLN B 1 47 ? 19.215 -43.647 44.409 1.00 154.63 ? 47 GLN B OE1 1 +ATOM 2266 N NE2 . GLN B 1 47 ? 19.468 -41.571 45.175 1.00 167.37 ? 47 GLN B NE2 1 +ATOM 2267 N N . PHE B 1 48 ? 21.688 -42.530 40.688 1.00 85.67 ? 48 PHE B N 1 +ATOM 2268 C CA . PHE B 1 48 ? 22.465 -43.020 39.573 1.00 86.62 ? 48 PHE B CA 1 +ATOM 2269 C C . PHE B 1 48 ? 22.253 -44.528 39.397 1.00 100.43 ? 48 PHE B C 1 +ATOM 2270 O O . PHE B 1 48 ? 21.745 -45.241 40.272 1.00 84.15 ? 48 PHE B O 1 +ATOM 2271 C CB . PHE B 1 48 ? 23.949 -42.746 39.802 1.00 77.54 ? 48 PHE B CB 1 +ATOM 2272 C CG . PHE B 1 48 ? 24.273 -41.327 39.823 1.00 67.19 ? 48 PHE B CG 1 +ATOM 2273 C CD1 . PHE B 1 48 ? 23.995 -40.583 40.957 1.00 77.82 ? 48 PHE B CD1 1 +ATOM 2274 C CD2 . PHE B 1 48 ? 24.806 -40.729 38.730 1.00 58.39 ? 48 PHE B CD2 1 +ATOM 2275 C CE1 . PHE B 1 48 ? 24.219 -39.234 40.984 1.00 90.97 ? 48 PHE B CE1 1 +ATOM 2276 C CE2 . PHE B 1 48 ? 25.080 -39.389 38.759 1.00 75.48 ? 48 PHE B CE2 1 +ATOM 2277 C CZ . PHE B 1 48 ? 24.777 -38.636 39.880 1.00 91.46 ? 48 PHE B CZ 1 +ATOM 2278 N N . LYS B 1 49 ? 22.703 -45.009 38.252 1.00 111.48 ? 49 LYS B N 1 +ATOM 2279 C CA . LYS B 1 49 ? 22.548 -46.403 37.915 1.00 99.64 ? 49 LYS B CA 1 +ATOM 2280 C C . LYS B 1 49 ? 23.580 -47.229 38.677 1.00 107.07 ? 49 LYS B C 1 +ATOM 2281 O O . LYS B 1 49 ? 24.702 -46.772 38.930 1.00 102.25 ? 49 LYS B O 1 +ATOM 2282 C CB . LYS B 1 49 ? 22.675 -46.596 36.399 1.00 105.58 ? 49 LYS B CB 1 +ATOM 2283 C CG . LYS B 1 49 ? 21.545 -45.920 35.628 1.00 103.83 ? 49 LYS B CG 1 +ATOM 2284 C CD . LYS B 1 49 ? 21.453 -46.221 34.139 1.00 99.34 ? 49 LYS B CD 1 +ATOM 2285 C CE . LYS B 1 49 ? 20.157 -45.594 33.633 1.00 97.36 ? 49 LYS B CE 1 +ATOM 2286 N NZ . LYS B 1 49 ? 19.856 -45.828 32.199 1.00 112.97 ? 49 LYS B NZ 1 +ATOM 2287 N N . PRO B 1 50 ? 23.200 -48.461 39.036 1.00 119.29 ? 50 PRO B N 1 +ATOM 2288 C CA . PRO B 1 50 ? 24.088 -49.373 39.755 1.00 117.27 ? 50 PRO B CA 1 +ATOM 2289 C C . PRO B 1 50 ? 25.081 -50.078 38.828 1.00 81.75 ? 50 PRO B C 1 +ATOM 2290 O O . PRO B 1 50 ? 24.938 -50.003 37.595 1.00 71.84 ? 50 PRO B O 1 +ATOM 2291 C CB . PRO B 1 50 ? 23.118 -50.382 40.368 1.00 122.34 ? 50 PRO B CB 1 +ATOM 2292 C CG . PRO B 1 50 ? 21.949 -50.396 39.436 1.00 114.94 ? 50 PRO B CG 1 +ATOM 2293 C CD . PRO B 1 50 ? 21.836 -49.007 38.882 1.00 111.44 ? 50 PRO B CD 1 +ATOM 2294 N N . TYR B 1 51 ? 26.063 -50.748 39.422 1.00 51.97 ? 51 TYR B N 1 +ATOM 2295 C CA . TYR B 1 51 ? 26.947 -51.566 38.652 1.00 50.19 ? 51 TYR B CA 1 +ATOM 2296 C C . TYR B 1 51 ? 26.114 -52.487 37.798 1.00 51.56 ? 51 TYR B C 1 +ATOM 2297 O O . TYR B 1 51 ? 25.144 -53.079 38.288 1.00 39.18 ? 51 TYR B O 1 +ATOM 2298 C CB . TYR B 1 51 ? 27.877 -52.387 39.553 1.00 60.80 ? 51 TYR B CB 1 +ATOM 2299 C CG . TYR B 1 51 ? 29.028 -53.006 38.766 1.00 71.10 ? 51 TYR B CG 1 +ATOM 2300 C CD1 . TYR B 1 51 ? 30.186 -52.279 38.535 1.00 93.23 ? 51 TYR B CD1 1 +ATOM 2301 C CD2 . TYR B 1 51 ? 28.942 -54.282 38.212 1.00 74.76 ? 51 TYR B CD2 1 +ATOM 2302 C CE1 . TYR B 1 51 ? 31.223 -52.775 37.763 1.00 95.72 ? 51 TYR B CE1 1 +ATOM 2303 C CE2 . TYR B 1 51 ? 29.993 -54.810 37.454 1.00 79.61 ? 51 TYR B CE2 1 +ATOM 2304 C CZ . TYR B 1 51 ? 31.123 -54.027 37.217 1.00 101.41 ? 51 TYR B CZ 1 +ATOM 2305 O OH . TYR B 1 51 ? 32.205 -54.475 36.486 1.00 120.62 ? 51 TYR B OH 1 +ATOM 2306 N N . PRO B 1 52 ? 26.485 -52.655 36.506 1.00 63.44 ? 52 PRO B N 1 +ATOM 2307 C CA . PRO B 1 52 ? 27.686 -52.208 35.804 1.00 64.77 ? 52 PRO B CA 1 +ATOM 2308 C C . PRO B 1 52 ? 27.607 -50.900 35.049 1.00 70.91 ? 52 PRO B C 1 +ATOM 2309 O O . PRO B 1 52 ? 28.479 -50.645 34.212 1.00 62.81 ? 52 PRO B O 1 +ATOM 2310 C CB . PRO B 1 52 ? 27.917 -53.321 34.789 1.00 78.32 ? 52 PRO B CB 1 +ATOM 2311 C CG . PRO B 1 52 ? 26.538 -53.755 34.420 1.00 87.40 ? 52 PRO B CG 1 +ATOM 2312 C CD . PRO B 1 52 ? 25.712 -53.609 35.679 1.00 81.20 ? 52 PRO B CD 1 +ATOM 2313 N N . ALA B 1 53 ? 26.650 -50.043 35.386 1.00 79.15 ? 53 ALA B N 1 +ATOM 2314 C CA . ALA B 1 53 ? 26.601 -48.728 34.757 1.00 83.22 ? 53 ALA B CA 1 +ATOM 2315 C C . ALA B 1 53 ? 27.760 -47.872 35.200 1.00 76.07 ? 53 ALA B C 1 +ATOM 2316 O O . ALA B 1 53 ? 28.450 -48.154 36.209 1.00 66.31 ? 53 ALA B O 1 +ATOM 2317 C CB . ALA B 1 53 ? 25.329 -48.008 35.092 1.00 100.16 ? 53 ALA B CB 1 +ATOM 2318 N N . SER B 1 54 ? 28.043 -46.854 34.392 1.00 64.69 ? 54 SER B N 1 +ATOM 2319 C CA . SER B 1 54 ? 29.043 -45.886 34.815 1.00 52.42 ? 54 SER B CA 1 +ATOM 2320 C C . SER B 1 54 ? 28.549 -45.281 36.127 1.00 39.95 ? 54 SER B C 1 +ATOM 2321 O O . SER B 1 54 ? 27.379 -45.035 36.305 1.00 33.11 ? 54 SER B O 1 +ATOM 2322 C CB . SER B 1 54 ? 29.314 -44.811 33.749 1.00 46.62 ? 54 SER B CB 1 +ATOM 2323 O OG . SER B 1 54 ? 29.858 -43.616 34.321 1.00 35.45 ? 54 SER B OG 1 +ATOM 2324 N N . ASN B 1 55 ? 29.502 -45.029 37.009 1.00 39.62 ? 55 ASN B N 1 +ATOM 2325 C CA . ASN B 1 55 ? 29.286 -44.317 38.238 1.00 38.18 ? 55 ASN B CA 1 +ATOM 2326 C C . ASN B 1 55 ? 28.474 -43.056 38.038 1.00 40.14 ? 55 ASN B C 1 +ATOM 2327 O O . ASN B 1 55 ? 27.674 -42.647 38.886 1.00 40.31 ? 55 ASN B O 1 +ATOM 2328 C CB . ASN B 1 55 ? 30.651 -43.954 38.817 1.00 39.10 ? 55 ASN B CB 1 +ATOM 2329 C CG . ASN B 1 55 ? 30.565 -43.547 40.236 1.00 61.24 ? 55 ASN B CG 1 +ATOM 2330 O OD1 . ASN B 1 55 ? 29.583 -43.826 40.947 1.00 108.68 ? 55 ASN B OD1 1 +ATOM 2331 N ND2 . ASN B 1 55 ? 31.644 -42.986 40.717 1.00 72.45 ? 55 ASN B ND2 1 +ATOM 2332 N N . PHE B 1 56 ? 28.629 -42.463 36.855 1.00 48.43 ? 56 PHE B N 1 +ATOM 2333 C CA . PHE B 1 56 ? 28.074 -41.145 36.556 1.00 55.79 ? 56 PHE B CA 1 +ATOM 2334 C C . PHE B 1 56 ? 26.764 -41.200 35.785 1.00 68.64 ? 56 PHE B C 1 +ATOM 2335 O O . PHE B 1 56 ? 26.235 -40.156 35.374 1.00 72.53 ? 56 PHE B O 1 +ATOM 2336 C CB . PHE B 1 56 ? 29.047 -40.339 35.715 1.00 57.79 ? 56 PHE B CB 1 +ATOM 2337 C CG . PHE B 1 56 ? 30.383 -40.147 36.358 1.00 59.19 ? 56 PHE B CG 1 +ATOM 2338 C CD1 . PHE B 1 56 ? 30.521 -39.515 37.591 1.00 46.05 ? 56 PHE B CD1 1 +ATOM 2339 C CD2 . PHE B 1 56 ? 31.507 -40.597 35.712 1.00 81.20 ? 56 PHE B CD2 1 +ATOM 2340 C CE1 . PHE B 1 56 ? 31.750 -39.368 38.180 1.00 47.02 ? 56 PHE B CE1 1 +ATOM 2341 C CE2 . PHE B 1 56 ? 32.756 -40.410 36.281 1.00 82.67 ? 56 PHE B CE2 1 +ATOM 2342 C CZ . PHE B 1 56 ? 32.875 -39.795 37.518 1.00 61.56 ? 56 PHE B CZ 1 +ATOM 2343 N N . SER B 1 57 ? 26.281 -42.400 35.478 1.00 69.37 ? 57 SER B N 1 +ATOM 2344 C CA . SER B 1 57 ? 25.057 -42.508 34.681 1.00 71.80 ? 57 SER B CA 1 +ATOM 2345 C C . SER B 1 57 ? 23.885 -42.226 35.614 1.00 77.94 ? 57 SER B C 1 +ATOM 2346 O O . SER B 1 57 ? 23.632 -42.964 36.557 1.00 58.31 ? 57 SER B O 1 +ATOM 2347 C CB . SER B 1 57 ? 24.931 -43.886 34.008 1.00 68.01 ? 57 SER B CB 1 +ATOM 2348 O OG . SER B 1 57 ? 25.808 -43.970 32.897 1.00 66.21 ? 57 SER B OG 1 +ATOM 2349 N N . THR B 1 58 ? 23.153 -41.155 35.322 1.00 83.38 ? 58 THR B N 1 +ATOM 2350 C CA . THR B 1 58 ? 22.006 -40.785 36.132 1.00 65.42 ? 58 THR B CA 1 +ATOM 2351 C C . THR B 1 58 ? 20.849 -41.723 35.883 1.00 74.15 ? 58 THR B C 1 +ATOM 2352 O O . THR B 1 58 ? 20.696 -42.316 34.821 1.00 48.84 ? 58 THR B O 1 +ATOM 2353 C CB . THR B 1 58 ? 21.506 -39.402 35.771 1.00 49.67 ? 58 THR B CB 1 +ATOM 2354 O OG1 . THR B 1 58 ? 21.105 -39.379 34.401 1.00 41.19 ? 58 THR B OG1 1 +ATOM 2355 C CG2 . THR B 1 58 ? 22.582 -38.438 35.963 1.00 50.87 ? 58 THR B CG2 1 +ATOM 2356 N N . ALA B 1 59 ? 20.016 -41.887 36.879 1.00 80.35 ? 59 ALA B N 1 +ATOM 2357 C CA . ALA B 1 59 ? 18.968 -42.863 36.717 1.00 87.46 ? 59 ALA B CA 1 +ATOM 2358 C C . ALA B 1 59 ? 17.863 -42.298 35.837 1.00 82.21 ? 59 ALA B C 1 +ATOM 2359 O O . ALA B 1 59 ? 17.044 -43.034 35.296 1.00 90.41 ? 59 ALA B O 1 +ATOM 2360 C CB . ALA B 1 59 ? 18.432 -43.282 38.063 1.00 103.39 ? 59 ALA B CB 1 +ATOM 2361 N N . VAL B 1 60 ? 17.821 -40.974 35.739 1.00 84.61 ? 60 VAL B N 1 +ATOM 2362 C CA . VAL B 1 60 ? 16.725 -40.266 35.082 1.00 82.36 ? 60 VAL B CA 1 +ATOM 2363 C C . VAL B 1 60 ? 17.327 -39.246 34.113 1.00 85.74 ? 60 VAL B C 1 +ATOM 2364 O O . VAL B 1 60 ? 18.324 -38.598 34.424 1.00 87.30 ? 60 VAL B O 1 +ATOM 2365 C CB . VAL B 1 60 ? 15.878 -39.522 36.131 1.00 74.12 ? 60 VAL B CB 1 +ATOM 2366 C CG1 . VAL B 1 60 ? 14.745 -38.755 35.480 1.00 79.67 ? 60 VAL B CG1 1 +ATOM 2367 C CG2 . VAL B 1 60 ? 15.339 -40.496 37.143 1.00 89.32 ? 60 VAL B CG2 1 +ATOM 2368 N N . PRO B 1 61 ? 16.743 -39.126 32.917 1.00 82.74 ? 61 PRO B N 1 +ATOM 2369 C CA . PRO B 1 61 ? 17.293 -38.149 31.997 1.00 80.67 ? 61 PRO B CA 1 +ATOM 2370 C C . PRO B 1 61 ? 17.214 -36.734 32.545 1.00 75.98 ? 61 PRO B C 1 +ATOM 2371 O O . PRO B 1 61 ? 16.171 -36.354 33.153 1.00 112.84 ? 61 PRO B O 1 +ATOM 2372 C CB . PRO B 1 61 ? 16.412 -38.329 30.734 1.00 94.69 ? 61 PRO B CB 1 +ATOM 2373 C CG . PRO B 1 61 ? 15.152 -38.994 31.205 1.00 73.79 ? 61 PRO B CG 1 +ATOM 2374 C CD . PRO B 1 61 ? 15.602 -39.869 32.338 1.00 74.65 ? 61 PRO B CD 1 +ATOM 2375 N N . GLN B 1 62 ? 18.214 -35.927 32.190 1.00 66.78 ? 62 GLN B N 1 +ATOM 2376 C CA . GLN B 1 62 ? 18.272 -34.532 32.628 1.00 68.19 ? 62 GLN B CA 1 +ATOM 2377 C C . GLN B 1 62 ? 17.539 -33.607 31.680 1.00 63.15 ? 62 GLN B C 1 +ATOM 2378 O O . GLN B 1 62 ? 17.915 -32.463 31.521 1.00 41.22 ? 62 GLN B O 1 +ATOM 2379 C CB . GLN B 1 62 ? 19.716 -34.078 32.690 1.00 92.23 ? 62 GLN B CB 1 +ATOM 2380 C CG . GLN B 1 62 ? 20.627 -35.043 33.427 1.00 116.78 ? 62 GLN B CG 1 +ATOM 2381 C CD . GLN B 1 62 ? 20.165 -35.276 34.853 1.00 127.79 ? 62 GLN B CD 1 +ATOM 2382 O OE1 . GLN B 1 62 ? 20.391 -34.454 35.735 1.00 117.31 ? 62 GLN B OE1 1 +ATOM 2383 N NE2 . GLN B 1 62 ? 19.498 -36.389 35.078 1.00 141.56 ? 62 GLN B NE2 1 +ATOM 2384 N N . SER B 1 63 ? 16.404 -34.074 31.139 1.00 93.40 ? 63 SER B N 1 +ATOM 2385 C CA . SER B 1 63 ? 15.740 -33.426 29.990 1.00 73.23 ? 63 SER B CA 1 +ATOM 2386 C C . SER B 1 63 ? 14.285 -33.057 30.292 1.00 77.42 ? 63 SER B C 1 +ATOM 2387 O O . SER B 1 63 ? 13.587 -32.529 29.428 1.00 87.58 ? 63 SER B O 1 +ATOM 2388 C CB . SER B 1 63 ? 15.790 -34.356 28.778 1.00 48.40 ? 63 SER B CB 1 +ATOM 2389 O OG . SER B 1 63 ? 15.078 -35.539 29.027 1.00 31.71 ? 63 SER B OG 1 +ATOM 2390 N N . ALA B 1 64 ? 13.904 -33.149 31.566 1.00 90.14 ? 64 ALA B N 1 +ATOM 2391 C CA . ALA B 1 64 ? 12.552 -32.819 31.999 1.00 102.66 ? 64 ALA B CA 1 +ATOM 2392 C C . ALA B 1 64 ? 12.027 -31.427 31.556 1.00 142.69 ? 64 ALA B C 1 +ATOM 2393 O O . ALA B 1 64 ? 10.851 -31.274 31.170 1.00 151.97 ? 64 ALA B O 1 +ATOM 2394 C CB . ALA B 1 64 ? 12.457 -32.942 33.511 1.00 112.11 ? 64 ALA B CB 1 +ATOM 2395 N N . THR B 1 65 ? 12.889 -30.414 31.649 1.00 132.10 ? 65 THR B N 1 +ATOM 2396 C CA . THR B 1 65 ? 12.537 -29.035 31.302 1.00 98.00 ? 65 THR B CA 1 +ATOM 2397 C C . THR B 1 65 ? 11.940 -28.935 29.907 1.00 102.04 ? 65 THR B C 1 +ATOM 2398 O O . THR B 1 65 ? 10.875 -28.350 29.714 1.00 101.24 ? 65 THR B O 1 +ATOM 2399 C CB . THR B 1 65 ? 13.790 -28.174 31.305 1.00 84.22 ? 65 THR B CB 1 +ATOM 2400 O OG1 . THR B 1 65 ? 14.610 -28.572 32.405 1.00 89.47 ? 65 THR B OG1 1 +ATOM 2401 C CG2 . THR B 1 65 ? 13.433 -26.701 31.405 1.00 83.84 ? 65 THR B CG2 1 +ATOM 2402 N N . ALA B 1 66 ? 12.622 -29.539 28.941 1.00 105.90 ? 66 ALA B N 1 +ATOM 2403 C CA . ALA B 1 66 ? 12.176 -29.476 27.572 1.00 100.25 ? 66 ALA B CA 1 +ATOM 2404 C C . ALA B 1 66 ? 10.877 -30.285 27.345 1.00 73.95 ? 66 ALA B C 1 +ATOM 2405 O O . ALA B 1 66 ? 10.018 -29.875 26.550 1.00 52.65 ? 66 ALA B O 1 +ATOM 2406 C CB . ALA B 1 66 ? 13.286 -29.951 26.657 1.00 122.04 ? 66 ALA B CB 1 +ATOM 2407 N N . MET B 1 67 ? 10.750 -31.401 28.062 1.00 55.66 ? 67 MET B N 1 +ATOM 2408 C CA . MET B 1 67 ? 9.564 -32.220 27.983 1.00 61.77 ? 67 MET B CA 1 +ATOM 2409 C C . MET B 1 67 ? 8.378 -31.424 28.515 1.00 71.61 ? 67 MET B C 1 +ATOM 2410 O O . MET B 1 67 ? 7.257 -31.469 27.920 1.00 109.16 ? 67 MET B O 1 +ATOM 2411 C CB . MET B 1 67 ? 9.709 -33.492 28.805 1.00 65.60 ? 67 MET B CB 1 +ATOM 2412 C CG . MET B 1 67 ? 10.670 -34.536 28.242 1.00 56.21 ? 67 MET B CG 1 +ATOM 2413 S SD . MET B 1 67 ? 11.013 -35.824 29.491 1.00 80.87 ? 67 MET B SD 1 +ATOM 2414 C CE . MET B 1 67 ? 11.980 -36.978 28.533 1.00 64.11 ? 67 MET B CE 1 +ATOM 2415 N N . LEU B 1 68 ? 8.596 -30.679 29.606 1.00 48.55 ? 68 LEU B N 1 +ATOM 2416 C CA . LEU B 1 68 ? 7.512 -29.881 30.156 1.00 60.61 ? 68 LEU B CA 1 +ATOM 2417 C C . LEU B 1 68 ? 7.076 -28.776 29.176 1.00 76.25 ? 68 LEU B C 1 +ATOM 2418 O O . LEU B 1 68 ? 5.869 -28.549 28.991 1.00 100.75 ? 68 LEU B O 1 +ATOM 2419 C CB . LEU B 1 68 ? 7.883 -29.241 31.475 1.00 54.47 ? 68 LEU B CB 1 +ATOM 2420 C CG . LEU B 1 68 ? 6.850 -28.201 31.985 1.00 58.53 ? 68 LEU B CG 1 +ATOM 2421 C CD1 . LEU B 1 68 ? 5.513 -28.870 32.347 1.00 55.82 ? 68 LEU B CD1 1 +ATOM 2422 C CD2 . LEU B 1 68 ? 7.368 -27.393 33.171 1.00 53.68 ? 68 LEU B CD2 1 +ATOM 2423 N N . VAL B 1 69 ? 8.038 -28.087 28.575 1.00 70.48 ? 69 VAL B N 1 +ATOM 2424 C CA . VAL B 1 69 ? 7.731 -27.005 27.635 1.00 55.09 ? 69 VAL B CA 1 +ATOM 2425 C C . VAL B 1 69 ? 6.997 -27.554 26.453 1.00 49.96 ? 69 VAL B C 1 +ATOM 2426 O O . VAL B 1 69 ? 5.953 -27.005 26.037 1.00 75.22 ? 69 VAL B O 1 +ATOM 2427 C CB . VAL B 1 69 ? 8.990 -26.329 27.095 1.00 67.91 ? 69 VAL B CB 1 +ATOM 2428 C CG1 . VAL B 1 69 ? 8.633 -25.374 25.985 1.00 56.09 ? 69 VAL B CG1 1 +ATOM 2429 C CG2 . VAL B 1 69 ? 9.744 -25.576 28.205 1.00 80.01 ? 69 VAL B CG2 1 +ATOM 2430 N N . THR B 1 70 ? 7.462 -28.688 25.959 1.00 47.46 ? 70 THR B N 1 +ATOM 2431 C CA . THR B 1 70 ? 6.723 -29.394 24.902 1.00 76.76 ? 70 THR B CA 1 +ATOM 2432 C C . THR B 1 70 ? 5.264 -29.838 25.243 1.00 56.94 ? 70 THR B C 1 +ATOM 2433 O O . THR B 1 70 ? 4.329 -29.585 24.475 1.00 42.47 ? 70 THR B O 1 +ATOM 2434 C CB . THR B 1 70 ? 7.505 -30.626 24.445 1.00 109.26 ? 70 THR B CB 1 +ATOM 2435 O OG1 . THR B 1 70 ? 8.843 -30.219 24.120 1.00 103.39 ? 70 THR B OG1 1 +ATOM 2436 C CG2 . THR B 1 70 ? 6.833 -31.287 23.205 1.00 118.43 ? 70 THR B CG2 1 +ATOM 2437 N N . ALA B 1 71 ? 5.084 -30.422 26.416 1.00 46.53 ? 71 ALA B N 1 +ATOM 2438 C CA . ALA B 1 71 ? 3.752 -30.744 26.895 1.00 47.43 ? 71 ALA B CA 1 +ATOM 2439 C C . ALA B 1 71 ? 2.854 -29.517 27.075 1.00 48.97 ? 71 ALA B C 1 +ATOM 2440 O O . ALA B 1 71 ? 1.681 -29.525 26.660 1.00 56.36 ? 71 ALA B O 1 +ATOM 2441 C CB . ALA B 1 71 ? 3.842 -31.477 28.209 1.00 58.74 ? 71 ALA B CB 1 +ATOM 2442 N N . LEU B 1 72 ? 3.406 -28.452 27.650 1.00 55.18 ? 72 LEU B N 1 +ATOM 2443 C CA . LEU B 1 72 ? 2.690 -27.158 27.714 1.00 67.16 ? 72 LEU B CA 1 +ATOM 2444 C C . LEU B 1 72 ? 2.286 -26.586 26.350 1.00 73.74 ? 72 LEU B C 1 +ATOM 2445 O O . LEU B 1 72 ? 1.260 -25.911 26.237 1.00 88.87 ? 72 LEU B O 1 +ATOM 2446 C CB . LEU B 1 72 ? 3.529 -26.090 28.403 1.00 61.96 ? 72 LEU B CB 1 +ATOM 2447 C CG . LEU B 1 72 ? 3.812 -26.371 29.860 1.00 61.05 ? 72 LEU B CG 1 +ATOM 2448 C CD1 . LEU B 1 72 ? 4.956 -25.506 30.306 1.00 62.89 ? 72 LEU B CD1 1 +ATOM 2449 C CD2 . LEU B 1 72 ? 2.602 -26.108 30.725 1.00 85.42 ? 72 LEU B CD2 1 +ATOM 2450 N N . LYS B 1 73 ? 3.043 -26.912 25.309 1.00 73.20 ? 73 LYS B N 1 +ATOM 2451 C CA . LYS B 1 73 ? 2.659 -26.508 23.974 1.00 92.49 ? 73 LYS B CA 1 +ATOM 2452 C C . LYS B 1 73 ? 1.597 -27.417 23.332 1.00 108.79 ? 73 LYS B C 1 +ATOM 2453 O O . LYS B 1 73 ? 0.641 -26.923 22.718 1.00 108.93 ? 73 LYS B O 1 +ATOM 2454 C CB . LYS B 1 73 ? 3.873 -26.467 23.068 1.00 92.80 ? 73 LYS B CB 1 +ATOM 2455 C CG . LYS B 1 73 ? 3.596 -25.779 21.750 1.00 111.20 ? 73 LYS B CG 1 +ATOM 2456 C CD . LYS B 1 73 ? 4.532 -26.299 20.693 1.00 99.31 ? 73 LYS B CD 1 +ATOM 2457 C CE . LYS B 1 73 ? 4.102 -27.657 20.091 1.00 105.52 ? 73 LYS B CE 1 +ATOM 2458 N NZ . LYS B 1 73 ? 3.516 -27.515 18.724 1.00 106.01 ? 73 LYS B NZ 1 +ATOM 2459 N N . ASP B 1 74 ? 1.800 -28.736 23.421 1.00 107.56 ? 74 ASP B N 1 +ATOM 2460 C CA . ASP B 1 74 ? 0.903 -29.715 22.787 1.00 101.59 ? 74 ASP B CA 1 +ATOM 2461 C C . ASP B 1 74 ? -0.524 -29.617 23.327 1.00 113.16 ? 74 ASP B C 1 +ATOM 2462 O O . ASP B 1 74 ? -1.481 -29.881 22.594 1.00 149.64 ? 74 ASP B O 1 +ATOM 2463 C CB . ASP B 1 74 ? 1.405 -31.134 23.006 1.00 111.01 ? 74 ASP B CB 1 +ATOM 2464 C CG . ASP B 1 74 ? 2.700 -31.429 22.255 1.00 145.25 ? 74 ASP B CG 1 +ATOM 2465 O OD1 . ASP B 1 74 ? 2.959 -30.831 21.176 1.00 168.99 ? 74 ASP B OD1 1 +ATOM 2466 O OD2 . ASP B 1 74 ? 3.456 -32.306 22.741 1.00 163.35 ? 74 ASP B OD2 1 +ATOM 2467 N N . SER B 1 75 ? -0.666 -29.150 24.573 1.00 110.05 ? 75 SER B N 1 +ATOM 2468 C CA . SER B 1 75 ? -1.984 -28.988 25.219 1.00 92.43 ? 75 SER B CA 1 +ATOM 2469 C C . SER B 1 75 ? -2.873 -27.948 24.546 1.00 90.25 ? 75 SER B C 1 +ATOM 2470 O O . SER B 1 75 ? -4.105 -28.028 24.610 1.00 93.53 ? 75 SER B O 1 +ATOM 2471 C CB . SER B 1 75 ? -1.822 -28.579 26.678 1.00 86.28 ? 75 SER B CB 1 +ATOM 2472 O OG . SER B 1 75 ? -1.710 -27.170 26.816 1.00 63.32 ? 75 SER B OG 1 +ATOM 2473 N N . ARG B 1 76 ? -2.240 -26.976 23.895 1.00 90.79 ? 76 ARG B N 1 +ATOM 2474 C CA . ARG B 1 76 ? -2.943 -25.922 23.182 1.00 101.41 ? 76 ARG B CA 1 +ATOM 2475 C C . ARG B 1 76 ? -3.683 -25.017 24.156 1.00 85.57 ? 76 ARG B C 1 +ATOM 2476 O O . ARG B 1 76 ? -4.776 -24.502 23.886 1.00 151.92 ? 76 ARG B O 1 +ATOM 2477 C CB . ARG B 1 76 ? -3.824 -26.493 22.048 1.00 119.10 ? 76 ARG B CB 1 +ATOM 2478 C CG . ARG B 1 76 ? -3.181 -26.313 20.664 1.00 138.64 ? 76 ARG B CG 1 +ATOM 2479 C CD . ARG B 1 76 ? -4.206 -25.861 19.639 1.00 175.90 ? 76 ARG B CD 1 +ATOM 2480 N NE . ARG B 1 76 ? -4.549 -24.427 19.624 1.00 167.41 ? 76 ARG B NE 1 +ATOM 2481 C CZ . ARG B 1 76 ? -4.425 -23.581 18.597 1.00 126.04 ? 76 ARG B CZ 1 +ATOM 2482 N NH1 . ARG B 1 76 ? -3.930 -23.949 17.408 1.00 91.39 ? 76 ARG B NH1 1 +ATOM 2483 N NH2 . ARG B 1 76 ? -4.808 -22.324 18.776 1.00 123.77 ? 76 ARG B NH2 1 +ATOM 2484 N N . TRP B 1 77 ? -3.072 -24.858 25.314 1.00 65.83 ? 77 TRP B N 1 +ATOM 2485 C CA . TRP B 1 77 ? -3.537 -23.925 26.316 1.00 81.75 ? 77 TRP B CA 1 +ATOM 2486 C C . TRP B 1 77 ? -2.504 -22.818 26.537 1.00 90.74 ? 77 TRP B C 1 +ATOM 2487 O O . TRP B 1 77 ? -2.862 -21.673 26.816 1.00 100.98 ? 77 TRP B O 1 +ATOM 2488 C CB . TRP B 1 77 ? -3.780 -24.671 27.630 1.00 92.07 ? 77 TRP B CB 1 +ATOM 2489 C CG . TRP B 1 77 ? -5.181 -25.145 27.809 1.00 101.75 ? 77 TRP B CG 1 +ATOM 2490 C CD1 . TRP B 1 77 ? -5.759 -26.220 27.215 1.00 105.41 ? 77 TRP B CD1 1 +ATOM 2491 C CD2 . TRP B 1 77 ? -6.185 -24.567 28.660 1.00 112.59 ? 77 TRP B CD2 1 +ATOM 2492 N NE1 . TRP B 1 77 ? -7.069 -26.340 27.621 1.00 101.28 ? 77 TRP B NE1 1 +ATOM 2493 C CE2 . TRP B 1 77 ? -7.355 -25.329 28.501 1.00 99.97 ? 77 TRP B CE2 1 +ATOM 2494 C CE3 . TRP B 1 77 ? -6.205 -23.473 29.538 1.00 116.47 ? 77 TRP B CE3 1 +ATOM 2495 C CZ2 . TRP B 1 77 ? -8.527 -25.042 29.190 1.00 100.66 ? 77 TRP B CZ2 1 +ATOM 2496 C CZ3 . TRP B 1 77 ? -7.369 -23.195 30.226 1.00 101.62 ? 77 TRP B CZ3 1 +ATOM 2497 C CH2 . TRP B 1 77 ? -8.513 -23.980 30.051 1.00 103.54 ? 77 TRP B CH2 1 +ATOM 2498 N N . PHE B 1 78 ? -1.226 -23.167 26.372 1.00 105.95 ? 78 PHE B N 1 +ATOM 2499 C CA . PHE B 1 78 ? -0.090 -22.282 26.694 1.00 86.31 ? 78 PHE B CA 1 +ATOM 2500 C C . PHE B 1 78 ? 0.852 -22.026 25.509 1.00 75.73 ? 78 PHE B C 1 +ATOM 2501 O O . PHE B 1 78 ? 1.074 -22.926 24.670 1.00 67.06 ? 78 PHE B O 1 +ATOM 2502 C CB . PHE B 1 78 ? 0.768 -22.908 27.775 1.00 79.47 ? 78 PHE B CB 1 +ATOM 2503 C CG . PHE B 1 78 ? 0.022 -23.274 29.012 1.00 83.55 ? 78 PHE B CG 1 +ATOM 2504 C CD1 . PHE B 1 78 ? -0.365 -22.305 29.915 1.00 96.89 ? 78 PHE B CD1 1 +ATOM 2505 C CD2 . PHE B 1 78 ? -0.227 -24.595 29.307 1.00 82.50 ? 78 PHE B CD2 1 +ATOM 2506 C CE1 . PHE B 1 78 ? -1.014 -22.647 31.083 1.00 102.38 ? 78 PHE B CE1 1 +ATOM 2507 C CE2 . PHE B 1 78 ? -0.892 -24.945 30.464 1.00 94.12 ? 78 PHE B CE2 1 +ATOM 2508 C CZ . PHE B 1 78 ? -1.275 -23.972 31.362 1.00 94.35 ? 78 PHE B CZ 1 +ATOM 2509 N N . ILE B 1 79 ? 1.358 -20.792 25.431 1.00 64.27 ? 79 ILE B N 1 +ATOM 2510 C CA . ILE B 1 79 ? 2.455 -20.438 24.543 1.00 73.30 ? 79 ILE B CA 1 +ATOM 2511 C C . ILE B 1 79 ? 3.689 -20.418 25.420 1.00 86.30 ? 79 ILE B C 1 +ATOM 2512 O O . ILE B 1 79 ? 3.662 -19.743 26.457 1.00 89.89 ? 79 ILE B O 1 +ATOM 2513 C CB . ILE B 1 79 ? 2.296 -19.037 23.949 1.00 76.03 ? 79 ILE B CB 1 +ATOM 2514 C CG1 . ILE B 1 79 ? 0.921 -18.867 23.298 1.00 97.72 ? 79 ILE B CG1 1 +ATOM 2515 C CG2 . ILE B 1 79 ? 3.382 -18.766 22.913 1.00 80.42 ? 79 ILE B CG2 1 +ATOM 2516 C CD1 . ILE B 1 79 ? 0.482 -17.411 23.190 1.00 126.95 ? 79 ILE B CD1 1 +ATOM 2517 N N . PRO B 1 80 ? 4.731 -21.222 25.057 1.00 74.83 ? 80 PRO B N 1 +ATOM 2518 C CA . PRO B 1 80 ? 5.875 -21.205 25.931 1.00 54.05 ? 80 PRO B CA 1 +ATOM 2519 C C . PRO B 1 80 ? 6.870 -20.220 25.443 1.00 53.96 ? 80 PRO B C 1 +ATOM 2520 O O . PRO B 1 80 ? 7.065 -20.107 24.239 1.00 82.14 ? 80 PRO B O 1 +ATOM 2521 C CB . PRO B 1 80 ? 6.424 -22.596 25.798 1.00 51.13 ? 80 PRO B CB 1 +ATOM 2522 C CG . PRO B 1 80 ? 5.268 -23.435 25.400 1.00 60.13 ? 80 PRO B CG 1 +ATOM 2523 C CD . PRO B 1 80 ? 4.564 -22.551 24.436 1.00 66.94 ? 80 PRO B CD 1 +ATOM 2524 N N . LEU B 1 81 ? 7.322 -19.370 26.347 1.00 42.70 ? 81 LEU B N 1 +ATOM 2525 C CA . LEU B 1 81 ? 8.327 -18.443 26.019 1.00 41.49 ? 81 LEU B CA 1 +ATOM 2526 C C . LEU B 1 81 ? 9.647 -19.088 26.338 1.00 66.74 ? 81 LEU B C 1 +ATOM 2527 O O . LEU B 1 81 ? 9.796 -19.809 27.363 1.00 47.38 ? 81 LEU B O 1 +ATOM 2528 C CB . LEU B 1 81 ? 8.136 -17.182 26.797 1.00 41.18 ? 81 LEU B CB 1 +ATOM 2529 C CG . LEU B 1 81 ? 6.763 -16.611 26.541 1.00 42.57 ? 81 LEU B CG 1 +ATOM 2530 C CD1 . LEU B 1 81 ? 6.555 -15.390 27.429 1.00 55.65 ? 81 LEU B CD1 1 +ATOM 2531 C CD2 . LEU B 1 81 ? 6.616 -16.214 25.101 1.00 42.24 ? 81 LEU B CD2 1 +ATOM 2532 N N . GLU B 1 82 ? 10.621 -18.823 25.448 1.00 122.90 ? 82 GLU B N 1 +ATOM 2533 C CA . GLU B 1 82 ? 11.974 -19.406 25.536 1.00 126.30 ? 82 GLU B CA 1 +ATOM 2534 C C . GLU B 1 82 ? 12.854 -18.725 26.600 1.00 87.59 ? 82 GLU B C 1 +ATOM 2535 O O . GLU B 1 82 ? 13.292 -17.591 26.422 1.00 40.50 ? 82 GLU B O 1 +ATOM 2536 C CB . GLU B 1 82 ? 12.693 -19.415 24.170 1.00 89.98 ? 82 GLU B CB 1 +ATOM 2537 C CG . GLU B 1 82 ? 14.080 -20.044 24.208 1.00 102.28 ? 82 GLU B CG 1 +ATOM 2538 C CD . GLU B 1 82 ? 14.088 -21.583 24.424 1.00 125.38 ? 82 GLU B CD 1 +ATOM 2539 O OE1 . GLU B 1 82 ? 13.447 -22.131 25.372 1.00 127.03 ? 82 GLU B OE1 1 +ATOM 2540 O OE2 . GLU B 1 82 ? 14.836 -22.274 23.686 1.00 138.80 ? 82 GLU B OE2 1 +ATOM 2541 N N . ARG B 1 83 ? 13.057 -19.457 27.707 1.00 77.36 ? 83 ARG B N 1 +ATOM 2542 C CA . ARG B 1 83 ? 13.938 -19.046 28.763 1.00 75.58 ? 83 ARG B CA 1 +ATOM 2543 C C . ARG B 1 83 ? 15.045 -20.065 29.067 1.00 77.59 ? 83 ARG B C 1 +ATOM 2544 O O . ARG B 1 83 ? 16.087 -19.698 29.628 1.00 57.83 ? 83 ARG B O 1 +ATOM 2545 C CB . ARG B 1 83 ? 13.142 -18.756 30.028 1.00 85.28 ? 83 ARG B CB 1 +ATOM 2546 C CG . ARG B 1 83 ? 12.038 -17.712 29.841 1.00 84.62 ? 83 ARG B CG 1 +ATOM 2547 C CD . ARG B 1 83 ? 12.587 -16.297 29.586 1.00 68.02 ? 83 ARG B CD 1 +ATOM 2548 N NE . ARG B 1 83 ? 11.531 -15.320 29.685 1.00 68.59 ? 83 ARG B NE 1 +ATOM 2549 C CZ . ARG B 1 83 ? 10.840 -14.845 28.662 1.00 89.26 ? 83 ARG B CZ 1 +ATOM 2550 N NH1 . ARG B 1 83 ? 11.221 -15.080 27.418 1.00 91.39 ? 83 ARG B NH1 1 +ATOM 2551 N NH2 . ARG B 1 83 ? 9.760 -14.099 28.897 1.00 119.27 ? 83 ARG B NH2 1 +ATOM 2552 N N . GLN B 1 84 ? 14.884 -21.315 28.651 1.00 85.28 ? 84 GLN B N 1 +ATOM 2553 C CA . GLN B 1 84 ? 15.972 -22.265 28.896 1.00 92.73 ? 84 GLN B CA 1 +ATOM 2554 C C . GLN B 1 84 ? 17.247 -21.766 28.216 1.00 80.00 ? 84 GLN B C 1 +ATOM 2555 O O . GLN B 1 84 ? 18.328 -21.865 28.771 1.00 91.49 ? 84 GLN B O 1 +ATOM 2556 C CB . GLN B 1 84 ? 15.613 -23.699 28.467 1.00 104.90 ? 84 GLN B CB 1 +ATOM 2557 C CG . GLN B 1 84 ? 16.275 -24.800 29.312 1.00 92.52 ? 84 GLN B CG 1 +ATOM 2558 C CD . GLN B 1 84 ? 15.961 -26.206 28.805 1.00 134.72 ? 84 GLN B CD 1 +ATOM 2559 O OE1 . GLN B 1 84 ? 14.870 -26.471 28.302 1.00 155.94 ? 84 GLN B OE1 1 +ATOM 2560 N NE2 . GLN B 1 84 ? 16.942 -27.099 28.889 1.00 163.68 ? 84 GLN B NE2 1 +ATOM 2561 N N . GLY B 1 85 ? 17.138 -21.251 27.003 1.00 64.74 ? 85 GLY B N 1 +ATOM 2562 C CA . GLY B 1 85 ? 18.331 -20.780 26.323 1.00 74.10 ? 85 GLY B CA 1 +ATOM 2563 C C . GLY B 1 85 ? 18.405 -19.270 26.223 1.00 70.15 ? 85 GLY B C 1 +ATOM 2564 O O . GLY B 1 85 ? 18.764 -18.733 25.165 1.00 62.26 ? 85 GLY B O 1 +ATOM 2565 N N . LEU B 1 86 ? 18.053 -18.575 27.300 1.00 65.43 ? 86 LEU B N 1 +ATOM 2566 C CA . LEU B 1 86 ? 17.731 -17.131 27.198 1.00 64.99 ? 86 LEU B CA 1 +ATOM 2567 C C . LEU B 1 86 ? 18.958 -16.366 26.776 1.00 85.75 ? 86 LEU B C 1 +ATOM 2568 O O . LEU B 1 86 ? 18.869 -15.377 26.040 1.00 110.54 ? 86 LEU B O 1 +ATOM 2569 C CB . LEU B 1 86 ? 17.210 -16.602 28.538 1.00 47.23 ? 86 LEU B CB 1 +ATOM 2570 C CG . LEU B 1 86 ? 17.035 -15.115 28.727 1.00 41.27 ? 86 LEU B CG 1 +ATOM 2571 C CD1 . LEU B 1 86 ? 16.054 -14.481 27.754 1.00 34.51 ? 86 LEU B CD1 1 +ATOM 2572 C CD2 . LEU B 1 86 ? 16.584 -14.843 30.154 1.00 54.52 ? 86 LEU B CD2 1 +ATOM 2573 N N . GLN B 1 87 ? 20.118 -16.857 27.199 1.00 103.60 ? 87 GLN B N 1 +ATOM 2574 C CA . GLN B 1 87 ? 21.365 -16.141 26.947 1.00 112.47 ? 87 GLN B CA 1 +ATOM 2575 C C . GLN B 1 87 ? 21.645 -15.996 25.429 1.00 115.51 ? 87 GLN B C 1 +ATOM 2576 O O . GLN B 1 87 ? 22.020 -14.920 24.929 1.00 90.52 ? 87 GLN B O 1 +ATOM 2577 C CB . GLN B 1 87 ? 22.516 -16.835 27.682 1.00 112.50 ? 87 GLN B CB 1 +ATOM 2578 C CG . GLN B 1 87 ? 23.586 -15.873 28.181 1.00 111.95 ? 87 GLN B CG 1 +ATOM 2579 C CD . GLN B 1 87 ? 23.000 -14.606 28.800 1.00 116.51 ? 87 GLN B CD 1 +ATOM 2580 O OE1 . GLN B 1 87 ? 22.240 -14.667 29.778 1.00 145.42 ? 87 GLN B OE1 1 +ATOM 2581 N NE2 . GLN B 1 87 ? 23.383 -13.446 28.266 1.00 105.29 ? 87 GLN B NE2 1 +ATOM 2582 N N . ASN B 1 88 ? 21.408 -17.078 24.696 1.00 99.71 ? 88 ASN B N 1 +ATOM 2583 C CA . ASN B 1 88 ? 21.603 -17.085 23.254 1.00 96.31 ? 88 ASN B CA 1 +ATOM 2584 C C . ASN B 1 88 ? 20.620 -16.178 22.539 1.00 100.27 ? 88 ASN B C 1 +ATOM 2585 O O . ASN B 1 88 ? 20.964 -15.541 21.523 1.00 155.39 ? 88 ASN B O 1 +ATOM 2586 C CB . ASN B 1 88 ? 21.404 -18.492 22.711 1.00 89.05 ? 88 ASN B CB 1 +ATOM 2587 C CG . ASN B 1 88 ? 22.310 -19.491 23.372 1.00 72.53 ? 88 ASN B CG 1 +ATOM 2588 O OD1 . ASN B 1 88 ? 23.466 -19.186 23.651 1.00 59.37 ? 88 ASN B OD1 1 +ATOM 2589 N ND2 . ASN B 1 88 ? 21.797 -20.698 23.612 1.00 72.08 ? 88 ASN B ND2 1 +ATOM 2590 N N . LEU B 1 89 ? 19.397 -16.155 23.047 1.00 65.82 ? 89 LEU B N 1 +ATOM 2591 C CA . LEU B 1 89 ? 18.385 -15.309 22.494 1.00 72.18 ? 89 LEU B CA 1 +ATOM 2592 C C . LEU B 1 89 ? 18.803 -13.831 22.601 1.00 83.78 ? 89 LEU B C 1 +ATOM 2593 O O . LEU B 1 89 ? 18.713 -13.045 21.641 1.00 124.19 ? 89 LEU B O 1 +ATOM 2594 C CB . LEU B 1 89 ? 17.101 -15.550 23.263 1.00 85.91 ? 89 LEU B CB 1 +ATOM 2595 C CG . LEU B 1 89 ? 15.760 -15.364 22.535 1.00 79.58 ? 89 LEU B CG 1 +ATOM 2596 C CD1 . LEU B 1 89 ? 14.976 -14.240 23.171 1.00 65.49 ? 89 LEU B CD1 1 +ATOM 2597 C CD2 . LEU B 1 89 ? 15.933 -15.112 21.043 1.00 54.98 ? 89 LEU B CD2 1 +ATOM 2598 N N . LEU B 1 90 ? 19.372 -13.474 23.743 1.00 74.74 ? 90 LEU B N 1 +ATOM 2599 C CA . LEU B 1 90 ? 19.796 -12.099 23.977 1.00 64.68 ? 90 LEU B CA 1 +ATOM 2600 C C . LEU B 1 90 ? 21.019 -11.739 23.126 1.00 84.94 ? 90 LEU B C 1 +ATOM 2601 O O . LEU B 1 90 ? 21.205 -10.576 22.716 1.00 108.92 ? 90 LEU B O 1 +ATOM 2602 C CB . LEU B 1 90 ? 20.114 -11.897 25.451 1.00 47.33 ? 90 LEU B CB 1 +ATOM 2603 C CG . LEU B 1 90 ? 18.945 -12.137 26.385 1.00 38.74 ? 90 LEU B CG 1 +ATOM 2604 C CD1 . LEU B 1 90 ? 19.462 -12.363 27.791 1.00 45.38 ? 90 LEU B CD1 1 +ATOM 2605 C CD2 . LEU B 1 90 ? 17.991 -10.979 26.337 1.00 35.70 ? 90 LEU B CD2 1 +ATOM 2606 N N . ASN B 1 91 ? 21.848 -12.742 22.870 1.00 93.45 ? 91 ASN B N 1 +ATOM 2607 C CA . ASN B 1 91 ? 23.015 -12.566 22.031 1.00 102.50 ? 91 ASN B CA 1 +ATOM 2608 C C . ASN B 1 91 ? 22.631 -12.292 20.581 1.00 93.07 ? 91 ASN B C 1 +ATOM 2609 O O . ASN B 1 91 ? 23.140 -11.352 19.954 1.00 108.35 ? 91 ASN B O 1 +ATOM 2610 C CB . ASN B 1 91 ? 23.866 -13.825 22.113 1.00 108.31 ? 91 ASN B CB 1 +ATOM 2611 C CG . ASN B 1 91 ? 25.230 -13.590 22.673 1.00 139.61 ? 91 ASN B CG 1 +ATOM 2612 O OD1 . ASN B 1 91 ? 25.485 -12.630 23.425 1.00 124.46 ? 91 ASN B OD1 1 +ATOM 2613 N ND2 . ASN B 1 91 ? 26.124 -14.513 22.347 1.00 174.91 ? 91 ASN B ND2 1 +ATOM 2614 N N . GLU B 1 92 ? 21.745 -13.115 20.032 1.00 80.42 ? 92 GLU B N 1 +ATOM 2615 C CA . GLU B 1 92 ? 21.252 -12.875 18.667 1.00 75.59 ? 92 GLU B CA 1 +ATOM 2616 C C . GLU B 1 92 ? 20.654 -11.469 18.547 1.00 63.85 ? 92 GLU B C 1 +ATOM 2617 O O . GLU B 1 92 ? 20.758 -10.825 17.495 1.00 46.92 ? 92 GLU B O 1 +ATOM 2618 C CB . GLU B 1 92 ? 20.225 -13.943 18.238 1.00 72.58 ? 92 GLU B CB 1 +ATOM 2619 C CG . GLU B 1 92 ? 20.843 -15.126 17.520 1.00 84.07 ? 92 GLU B CG 1 +ATOM 2620 C CD . GLU B 1 92 ? 21.723 -14.718 16.315 1.00 84.33 ? 92 GLU B CD 1 +ATOM 2621 O OE1 . GLU B 1 92 ? 21.245 -14.069 15.359 1.00 66.69 ? 92 GLU B OE1 1 +ATOM 2622 O OE2 . GLU B 1 92 ? 22.903 -15.124 16.273 1.00 71.48 ? 92 GLU B OE2 1 +ATOM 2623 N N . ARG B 1 93 ? 19.996 -11.017 19.613 1.00 59.11 ? 93 ARG B N 1 +ATOM 2624 C CA . ARG B 1 93 ? 19.353 -9.719 19.590 1.00 70.63 ? 93 ARG B CA 1 +ATOM 2625 C C . ARG B 1 93 ? 20.414 -8.624 19.608 1.00 97.52 ? 93 ARG B C 1 +ATOM 2626 O O . ARG B 1 93 ? 20.246 -7.577 18.974 1.00 120.68 ? 93 ARG B O 1 +ATOM 2627 C CB . ARG B 1 93 ? 18.344 -9.610 20.730 1.00 67.07 ? 93 ARG B CB 1 +ATOM 2628 C CG . ARG B 1 93 ? 17.131 -10.490 20.477 1.00 113.48 ? 93 ARG B CG 1 +ATOM 2629 C CD . ARG B 1 93 ? 16.246 -10.708 21.688 1.00 140.47 ? 93 ARG B CD 1 +ATOM 2630 N NE . ARG B 1 93 ? 15.062 -9.857 21.645 1.00 128.34 ? 93 ARG B NE 1 +ATOM 2631 C CZ . ARG B 1 93 ? 14.968 -8.672 22.226 1.00 119.65 ? 93 ARG B CZ 1 +ATOM 2632 N NH1 . ARG B 1 93 ? 15.960 -8.183 22.983 1.00 105.37 ? 93 ARG B NH1 1 +ATOM 2633 N NH2 . ARG B 1 93 ? 13.829 -8.016 22.108 1.00 109.16 ? 93 ARG B NH2 1 +ATOM 2634 N N . LYS B 1 94 ? 21.544 -8.887 20.270 1.00 93.53 ? 94 LYS B N 1 +ATOM 2635 C CA . LYS B 1 94 ? 22.666 -7.941 20.240 1.00 76.60 ? 94 LYS B CA 1 +ATOM 2636 C C . LYS B 1 94 ? 23.202 -7.827 18.819 1.00 79.42 ? 94 LYS B C 1 +ATOM 2637 O O . LYS B 1 94 ? 23.517 -6.727 18.349 1.00 81.46 ? 94 LYS B O 1 +ATOM 2638 C CB . LYS B 1 94 ? 23.788 -8.408 21.147 1.00 81.09 ? 94 LYS B CB 1 +ATOM 2639 C CG . LYS B 1 94 ? 23.703 -7.948 22.591 1.00 109.83 ? 94 LYS B CG 1 +ATOM 2640 C CD . LYS B 1 94 ? 24.776 -8.642 23.424 1.00 123.52 ? 94 LYS B CD 1 +ATOM 2641 C CE . LYS B 1 94 ? 25.087 -7.911 24.723 1.00 110.85 ? 94 LYS B CE 1 +ATOM 2642 N NZ . LYS B 1 94 ? 25.861 -8.798 25.635 1.00 110.43 ? 94 LYS B NZ 1 +ATOM 2643 N N . ILE B 1 95 ? 23.271 -8.962 18.122 1.00 83.29 ? 95 ILE B N 1 +ATOM 2644 C CA . ILE B 1 95 ? 23.873 -8.987 16.785 1.00 84.66 ? 95 ILE B CA 1 +ATOM 2645 C C . ILE B 1 95 ? 22.968 -8.331 15.770 1.00 82.07 ? 95 ILE B C 1 +ATOM 2646 O O . ILE B 1 95 ? 23.461 -7.602 14.878 1.00 74.88 ? 95 ILE B O 1 +ATOM 2647 C CB . ILE B 1 95 ? 24.175 -10.401 16.271 1.00 89.18 ? 95 ILE B CB 1 +ATOM 2648 C CG1 . ILE B 1 95 ? 24.924 -11.226 17.326 1.00 94.86 ? 95 ILE B CG1 1 +ATOM 2649 C CG2 . ILE B 1 95 ? 25.043 -10.283 15.038 1.00 95.24 ? 95 ILE B CG2 1 +ATOM 2650 C CD1 . ILE B 1 95 ? 25.544 -12.509 16.807 1.00 91.36 ? 95 ILE B CD1 1 +ATOM 2651 N N . ILE B 1 96 ? 21.656 -8.588 15.928 1.00 65.25 ? 96 ILE B N 1 +ATOM 2652 C CA . ILE B 1 96 ? 20.628 -7.901 15.153 1.00 53.31 ? 96 ILE B CA 1 +ATOM 2653 C C . ILE B 1 96 ? 20.753 -6.400 15.315 1.00 67.76 ? 96 ILE B C 1 +ATOM 2654 O O . ILE B 1 96 ? 20.997 -5.680 14.341 1.00 92.06 ? 96 ILE B O 1 +ATOM 2655 C CB . ILE B 1 96 ? 19.233 -8.283 15.566 1.00 38.03 ? 96 ILE B CB 1 +ATOM 2656 C CG1 . ILE B 1 96 ? 18.957 -9.719 15.206 1.00 37.83 ? 96 ILE B CG1 1 +ATOM 2657 C CG2 . ILE B 1 96 ? 18.248 -7.429 14.818 1.00 35.78 ? 96 ILE B CG2 1 +ATOM 2658 C CD1 . ILE B 1 96 ? 17.538 -10.175 15.517 1.00 40.48 ? 96 ILE B CD1 1 +ATOM 2659 N N . ARG B 1 97 ? 20.671 -5.921 16.555 1.00 67.57 ? 97 ARG B N 1 +ATOM 2660 C CA . ARG B 1 97 ? 20.741 -4.470 16.818 1.00 82.25 ? 97 ARG B CA 1 +ATOM 2661 C C . ARG B 1 97 ? 22.054 -3.823 16.316 1.00 83.29 ? 97 ARG B C 1 +ATOM 2662 O O . ARG B 1 97 ? 22.071 -2.662 15.902 1.00 70.86 ? 97 ARG B O 1 +ATOM 2663 C CB . ARG B 1 97 ? 20.563 -4.164 18.313 1.00 99.34 ? 97 ARG B CB 1 +ATOM 2664 C CG . ARG B 1 97 ? 19.169 -3.661 18.702 1.00 82.88 ? 97 ARG B CG 1 +ATOM 2665 C CD . ARG B 1 97 ? 19.110 -3.326 20.183 1.00 86.40 ? 97 ARG B CD 1 +ATOM 2666 N NE . ARG B 1 97 ? 18.930 -4.515 21.015 1.00 83.26 ? 97 ARG B NE 1 +ATOM 2667 C CZ . ARG B 1 97 ? 17.762 -4.927 21.504 1.00 102.33 ? 97 ARG B CZ 1 +ATOM 2668 N NH1 . ARG B 1 97 ? 16.647 -4.228 21.285 1.00 74.15 ? 97 ARG B NH1 1 +ATOM 2669 N NH2 . ARG B 1 97 ? 17.715 -6.056 22.227 1.00 128.16 ? 97 ARG B NH2 1 +ATOM 2670 N N . ALA B 1 98 ? 23.139 -4.585 16.335 1.00 80.11 ? 98 ALA B N 1 +ATOM 2671 C CA . ALA B 1 98 ? 24.404 -4.086 15.851 1.00 81.74 ? 98 ALA B CA 1 +ATOM 2672 C C . ALA B 1 98 ? 24.408 -4.039 14.328 1.00 88.00 ? 98 ALA B C 1 +ATOM 2673 O O . ALA B 1 98 ? 25.117 -3.223 13.722 1.00 65.22 ? 98 ALA B O 1 +ATOM 2674 C CB . ALA B 1 98 ? 25.521 -4.968 16.370 1.00 103.21 ? 98 ALA B CB 1 +ATOM 2675 N N . ALA B 1 99 ? 23.619 -4.930 13.717 1.00 111.36 ? 99 ALA B N 1 +ATOM 2676 C CA . ALA B 1 99 ? 23.521 -5.035 12.251 1.00 124.51 ? 99 ALA B CA 1 +ATOM 2677 C C . ALA B 1 99 ? 22.813 -3.848 11.634 1.00 103.92 ? 99 ALA B C 1 +ATOM 2678 O O . ALA B 1 99 ? 23.320 -3.207 10.715 1.00 117.54 ? 99 ALA B O 1 +ATOM 2679 C CB . ALA B 1 99 ? 22.797 -6.309 11.849 1.00 121.16 ? 99 ALA B CB 1 +ATOM 2680 N N . GLN B 1 100 ? 21.656 -3.526 12.187 1.00 109.12 ? 100 GLN B N 1 +ATOM 2681 C CA . GLN B 1 100 ? 20.726 -2.619 11.520 1.00 120.00 ? 100 GLN B CA 1 +ATOM 2682 C C . GLN B 1 100 ? 20.644 -1.231 12.147 1.00 89.51 ? 100 GLN B C 1 +ATOM 2683 O O . GLN B 1 100 ? 19.822 -0.407 11.724 1.00 121.87 ? 100 GLN B O 1 +ATOM 2684 C CB . GLN B 1 100 ? 19.325 -3.245 11.439 1.00 117.87 ? 100 GLN B CB 1 +ATOM 2685 C CG . GLN B 1 100 ? 18.863 -3.925 12.711 1.00 96.10 ? 100 GLN B CG 1 +ATOM 2686 C CD . GLN B 1 100 ? 17.884 -5.040 12.459 1.00 86.11 ? 100 GLN B CD 1 +ATOM 2687 O OE1 . GLN B 1 100 ? 18.160 -6.035 11.753 1.00 70.75 ? 100 GLN B OE1 1 +ATOM 2688 N NE2 . GLN B 1 100 ? 16.704 -4.881 13.037 1.00 96.98 ? 100 GLN B NE2 1 +ATOM 2689 N N . GLU B 1 101 ? 21.523 -0.945 13.098 1.00 70.61 ? 101 GLU B N 1 +ATOM 2690 C CA . GLU B 1 101 ? 21.500 0.359 13.771 1.00 86.24 ? 101 GLU B CA 1 +ATOM 2691 C C . GLU B 1 101 ? 21.883 1.521 12.846 1.00 83.45 ? 101 GLU B C 1 +ATOM 2692 O O . GLU B 1 101 ? 21.521 2.668 13.098 1.00 82.52 ? 101 GLU B O 1 +ATOM 2693 C CB . GLU B 1 101 ? 22.389 0.349 15.020 1.00 86.56 ? 101 GLU B CB 1 +ATOM 2694 C CG . GLU B 1 101 ? 23.809 -0.124 14.779 1.00 103.91 ? 101 GLU B CG 1 +ATOM 2695 C CD . GLU B 1 101 ? 24.679 -0.021 16.026 1.00 100.21 ? 101 GLU B CD 1 +ATOM 2696 O OE1 . GLU B 1 101 ? 24.111 0.056 17.128 1.00 102.49 ? 101 GLU B OE1 1 +ATOM 2697 O OE2 . GLU B 1 101 ? 25.928 -0.085 15.903 1.00 85.89 ? 101 GLU B OE2 1 +ATOM 2698 N N . ASN B 1 102 ? 22.616 1.226 11.782 1.00 90.03 ? 102 ASN B N 1 +ATOM 2699 C CA . ASN B 1 102 ? 23.086 2.266 10.884 1.00 95.81 ? 102 ASN B CA 1 +ATOM 2700 C C . ASN B 1 102 ? 22.165 2.510 9.710 1.00 91.15 ? 102 ASN B C 1 +ATOM 2701 O O . ASN B 1 102 ? 22.421 3.389 8.885 1.00 90.05 ? 102 ASN B O 1 +ATOM 2702 C CB . ASN B 1 102 ? 24.482 1.926 10.376 1.00 101.83 ? 102 ASN B CB 1 +ATOM 2703 C CG . ASN B 1 102 ? 25.529 2.076 11.456 1.00 103.69 ? 102 ASN B CG 1 +ATOM 2704 O OD1 . ASN B 1 102 ? 25.964 3.197 11.785 1.00 103.07 ? 102 ASN B OD1 1 +ATOM 2705 N ND2 . ASN B 1 102 ? 25.924 0.953 12.036 1.00 93.23 ? 102 ASN B ND2 1 +ATOM 2706 N N . GLY B 1 103 ? 21.097 1.732 9.619 1.00 100.74 ? 103 GLY B N 1 +ATOM 2707 C CA . GLY B 1 103 ? 20.158 1.876 8.507 1.00 128.22 ? 103 GLY B CA 1 +ATOM 2708 C C . GLY B 1 103 ? 20.778 1.681 7.130 1.00 109.79 ? 103 GLY B C 1 +ATOM 2709 O O . GLY B 1 103 ? 20.369 2.328 6.151 1.00 119.25 ? 103 GLY B O 1 +ATOM 2710 N N . THR B 1 104 ? 21.765 0.799 7.049 1.00 77.54 ? 104 THR B N 1 +ATOM 2711 C CA . THR B 1 104 ? 22.245 0.359 5.763 1.00 78.56 ? 104 THR B CA 1 +ATOM 2712 C C . THR B 1 104 ? 21.620 -0.984 5.430 1.00 82.85 ? 104 THR B C 1 +ATOM 2713 O O . THR B 1 104 ? 21.473 -1.309 4.247 1.00 133.02 ? 104 THR B O 1 +ATOM 2714 C CB . THR B 1 104 ? 23.776 0.281 5.701 1.00 73.00 ? 104 THR B CB 1 +ATOM 2715 O OG1 . THR B 1 104 ? 24.261 -0.722 6.614 1.00 102.58 ? 104 THR B OG1 1 +ATOM 2716 C CG2 . THR B 1 104 ? 24.371 1.629 6.054 1.00 73.58 ? 104 THR B CG2 1 +ATOM 2717 N N . VAL B 1 105 ? 21.201 -1.751 6.439 1.00 73.48 ? 105 VAL B N 1 +ATOM 2718 C CA . VAL B 1 105 ? 20.810 -3.166 6.194 1.00 97.73 ? 105 VAL B CA 1 +ATOM 2719 C C . VAL B 1 105 ? 19.595 -3.235 5.278 1.00 90.47 ? 105 VAL B C 1 +ATOM 2720 O O . VAL B 1 105 ? 18.710 -2.370 5.348 1.00 94.28 ? 105 VAL B O 1 +ATOM 2721 C CB . VAL B 1 105 ? 20.574 -3.985 7.501 1.00 110.47 ? 105 VAL B CB 1 +ATOM 2722 C CG1 . VAL B 1 105 ? 19.440 -4.997 7.328 1.00 92.63 ? 105 VAL B CG1 1 +ATOM 2723 C CG2 . VAL B 1 105 ? 21.866 -4.702 7.954 1.00 98.37 ? 105 VAL B CG2 1 +ATOM 2724 N N . ALA B 1 106 ? 19.627 -4.210 4.365 1.00 102.05 ? 106 ALA B N 1 +ATOM 2725 C CA . ALA B 1 106 ? 18.673 -4.305 3.266 1.00 130.06 ? 106 ALA B CA 1 +ATOM 2726 C C . ALA B 1 106 ? 17.261 -4.500 3.807 1.00 157.08 ? 106 ALA B C 1 +ATOM 2727 O O . ALA B 1 106 ? 17.044 -5.311 4.715 1.00 208.30 ? 106 ALA B O 1 +ATOM 2728 C CB . ALA B 1 106 ? 19.057 -5.458 2.351 1.00 120.23 ? 106 ALA B CB 1 +ATOM 2729 N N . ILE B 1 107 ? 16.313 -3.744 3.256 1.00 145.58 ? 107 ILE B N 1 +ATOM 2730 C CA . ILE B 1 107 ? 14.946 -3.709 3.767 1.00 151.78 ? 107 ILE B CA 1 +ATOM 2731 C C . ILE B 1 107 ? 14.273 -5.103 3.779 1.00 136.02 ? 107 ILE B C 1 +ATOM 2732 O O . ILE B 1 107 ? 13.427 -5.397 4.633 1.00 131.13 ? 107 ILE B O 1 +ATOM 2733 C CB . ILE B 1 107 ? 14.096 -2.696 2.961 1.00 141.05 ? 107 ILE B CB 1 +ATOM 2734 C CG1 . ILE B 1 107 ? 12.761 -2.415 3.662 1.00 166.08 ? 107 ILE B CG1 1 +ATOM 2735 C CG2 . ILE B 1 107 ? 13.856 -3.197 1.544 1.00 131.77 ? 107 ILE B CG2 1 +ATOM 2736 C CD1 . ILE B 1 107 ? 12.889 -1.892 5.082 1.00 160.09 ? 107 ILE B CD1 1 +ATOM 2737 N N . ASN B 1 108 ? 14.659 -5.955 2.837 1.00 123.15 ? 108 ASN B N 1 +ATOM 2738 C CA . ASN B 1 108 ? 14.179 -7.340 2.788 1.00 149.07 ? 108 ASN B CA 1 +ATOM 2739 C C . ASN B 1 108 ? 14.768 -8.171 3.929 1.00 152.93 ? 108 ASN B C 1 +ATOM 2740 O O . ASN B 1 108 ? 14.120 -9.073 4.465 1.00 157.50 ? 108 ASN B O 1 +ATOM 2741 C CB . ASN B 1 108 ? 14.564 -8.005 1.456 1.00 157.06 ? 108 ASN B CB 1 +ATOM 2742 C CG . ASN B 1 108 ? 14.636 -7.022 0.305 1.00 153.56 ? 108 ASN B CG 1 +ATOM 2743 O OD1 . ASN B 1 108 ? 13.631 -6.730 -0.336 1.00 174.13 ? 108 ASN B OD1 1 +ATOM 2744 N ND2 . ASN B 1 108 ? 15.827 -6.491 0.051 1.00 161.02 ? 108 ASN B ND2 1 +ATOM 2745 N N . ASN B 1 109 ? 16.015 -7.873 4.261 1.00 129.94 ? 109 ASN B N 1 +ATOM 2746 C CA . ASN B 1 109 ? 16.764 -8.632 5.247 1.00 121.07 ? 109 ASN B CA 1 +ATOM 2747 C C . ASN B 1 109 ? 16.522 -8.166 6.688 1.00 108.95 ? 109 ASN B C 1 +ATOM 2748 O O . ASN B 1 109 ? 16.823 -8.886 7.643 1.00 83.38 ? 109 ASN B O 1 +ATOM 2749 C CB . ASN B 1 109 ? 18.254 -8.543 4.923 1.00 133.38 ? 109 ASN B CB 1 +ATOM 2750 C CG . ASN B 1 109 ? 18.848 -9.887 4.562 1.00 160.94 ? 109 ASN B CG 1 +ATOM 2751 O OD1 . ASN B 1 109 ? 19.682 -10.420 5.295 1.00 224.16 ? 109 ASN B OD1 1 +ATOM 2752 N ND2 . ASN B 1 109 ? 18.387 -10.465 3.459 1.00 158.65 ? 109 ASN B ND2 1 +ATOM 2753 N N . ARG B 1 110 ? 15.947 -6.972 6.829 1.00 108.16 ? 110 ARG B N 1 +ATOM 2754 C CA . ARG B 1 110 ? 15.767 -6.309 8.131 1.00 86.12 ? 110 ARG B CA 1 +ATOM 2755 C C . ARG B 1 110 ? 14.973 -7.192 9.089 1.00 72.27 ? 110 ARG B C 1 +ATOM 2756 O O . ARG B 1 110 ? 13.926 -7.739 8.718 1.00 99.73 ? 110 ARG B O 1 +ATOM 2757 C CB . ARG B 1 110 ? 15.027 -4.966 7.916 1.00 70.23 ? 110 ARG B CB 1 +ATOM 2758 C CG . ARG B 1 110 ? 15.242 -3.941 9.007 1.00 71.77 ? 110 ARG B CG 1 +ATOM 2759 C CD . ARG B 1 110 ? 15.258 -2.522 8.454 1.00 84.17 ? 110 ARG B CD 1 +ATOM 2760 N NE . ARG B 1 110 ? 13.920 -1.922 8.406 1.00 105.61 ? 110 ARG B NE 1 +ATOM 2761 C CZ . ARG B 1 110 ? 13.528 -0.846 9.111 1.00 130.92 ? 110 ARG B CZ 1 +ATOM 2762 N NH1 . ARG B 1 110 ? 14.378 -0.180 9.901 1.00 120.67 ? 110 ARG B NH1 1 +ATOM 2763 N NH2 . ARG B 1 110 ? 12.272 -0.417 9.012 1.00 133.61 ? 110 ARG B NH2 1 +ATOM 2764 N N . ILE B 1 111 ? 15.430 -7.296 10.327 1.00 56.06 ? 111 ILE B N 1 +ATOM 2765 C CA . ILE B 1 111 ? 14.648 -7.985 11.376 1.00 72.54 ? 111 ILE B CA 1 +ATOM 2766 C C . ILE B 1 111 ? 14.090 -7.000 12.394 1.00 69.29 ? 111 ILE B C 1 +ATOM 2767 O O . ILE B 1 111 ? 14.861 -6.346 13.077 1.00 70.10 ? 111 ILE B O 1 +ATOM 2768 C CB . ILE B 1 111 ? 15.490 -9.028 12.145 1.00 77.38 ? 111 ILE B CB 1 +ATOM 2769 C CG1 . ILE B 1 111 ? 15.946 -10.112 11.169 1.00 99.67 ? 111 ILE B CG1 1 +ATOM 2770 C CG2 . ILE B 1 111 ? 14.696 -9.631 13.292 1.00 61.34 ? 111 ILE B CG2 1 +ATOM 2771 C CD1 . ILE B 1 111 ? 17.023 -11.026 11.715 1.00 101.41 ? 111 ILE B CD1 1 +ATOM 2772 N N . PRO B 1 112 ? 12.756 -6.900 12.498 1.00 72.34 ? 112 PRO B N 1 +ATOM 2773 C CA . PRO B 1 112 ? 12.171 -5.924 13.396 1.00 68.52 ? 112 PRO B CA 1 +ATOM 2774 C C . PRO B 1 112 ? 12.176 -6.475 14.814 1.00 75.21 ? 112 PRO B C 1 +ATOM 2775 O O . PRO B 1 112 ? 11.734 -7.612 15.056 1.00 73.71 ? 112 PRO B O 1 +ATOM 2776 C CB . PRO B 1 112 ? 10.756 -5.788 12.862 1.00 85.50 ? 112 PRO B CB 1 +ATOM 2777 C CG . PRO B 1 112 ? 10.436 -7.148 12.277 1.00 78.48 ? 112 PRO B CG 1 +ATOM 2778 C CD . PRO B 1 112 ? 11.736 -7.740 11.832 1.00 68.71 ? 112 PRO B CD 1 +ATOM 2779 N N . LEU B 1 113 ? 12.651 -5.663 15.746 1.00 92.87 ? 113 LEU B N 1 +ATOM 2780 C CA . LEU B 1 113 ? 12.832 -6.098 17.118 1.00 99.75 ? 113 LEU B CA 1 +ATOM 2781 C C . LEU B 1 113 ? 11.802 -5.470 18.052 1.00 95.15 ? 113 LEU B C 1 +ATOM 2782 O O . LEU B 1 113 ? 11.534 -4.255 18.035 1.00 64.43 ? 113 LEU B O 1 +ATOM 2783 C CB . LEU B 1 113 ? 14.256 -5.792 17.614 1.00 114.83 ? 113 LEU B CB 1 +ATOM 2784 C CG . LEU B 1 113 ? 15.304 -6.849 17.296 1.00 126.55 ? 113 LEU B CG 1 +ATOM 2785 C CD1 . LEU B 1 113 ? 16.610 -6.425 17.935 1.00 121.27 ? 113 LEU B CD1 1 +ATOM 2786 C CD2 . LEU B 1 113 ? 14.911 -8.239 17.776 1.00 146.91 ? 113 LEU B CD2 1 +ATOM 2787 N N . GLN B 1 114 ? 11.381 -6.302 18.987 1.00 95.54 ? 114 GLN B N 1 +ATOM 2788 C CA . GLN B 1 114 ? 10.302 -5.983 19.877 1.00 75.08 ? 114 GLN B CA 1 +ATOM 2789 C C . GLN B 1 114 ? 10.697 -6.574 21.228 1.00 75.49 ? 114 GLN B C 1 +ATOM 2790 O O . GLN B 1 114 ? 11.469 -7.525 21.283 1.00 78.32 ? 114 GLN B O 1 +ATOM 2791 C CB . GLN B 1 114 ? 9.061 -6.666 19.355 1.00 68.02 ? 114 GLN B CB 1 +ATOM 2792 C CG . GLN B 1 114 ? 7.813 -5.930 19.667 1.00 75.42 ? 114 GLN B CG 1 +ATOM 2793 C CD . GLN B 1 114 ? 6.675 -6.878 19.741 1.00 89.48 ? 114 GLN B CD 1 +ATOM 2794 O OE1 . GLN B 1 114 ? 6.688 -7.929 19.080 1.00 80.96 ? 114 GLN B OE1 1 +ATOM 2795 N NE2 . GLN B 1 114 ? 5.671 -6.548 20.578 1.00 108.76 ? 114 GLN B NE2 1 +ATOM 2796 N N . SER B 1 115 ? 10.249 -5.946 22.307 1.00 72.69 ? 115 SER B N 1 +ATOM 2797 C CA . SER B 1 115 ? 10.664 -6.317 23.673 1.00 55.05 ? 115 SER B CA 1 +ATOM 2798 C C . SER B 1 115 ? 10.289 -7.738 23.894 1.00 61.07 ? 115 SER B C 1 +ATOM 2799 O O . SER B 1 115 ? 9.399 -8.283 23.188 1.00 103.08 ? 115 SER B O 1 +ATOM 2800 C CB . SER B 1 115 ? 9.955 -5.433 24.706 1.00 64.09 ? 115 SER B CB 1 +ATOM 2801 O OG . SER B 1 115 ? 8.526 -5.370 24.478 1.00 76.44 ? 115 SER B OG 1 +ATOM 2802 N N . LEU B 1 116 ? 10.937 -8.384 24.846 1.00 76.73 ? 116 LEU B N 1 +ATOM 2803 C CA . LEU B 1 116 ? 10.822 -9.849 24.887 1.00 104.51 ? 116 LEU B CA 1 +ATOM 2804 C C . LEU B 1 116 ? 9.489 -10.165 25.494 1.00 92.33 ? 116 LEU B C 1 +ATOM 2805 O O . LEU B 1 116 ? 9.147 -9.538 26.490 1.00 102.06 ? 116 LEU B O 1 +ATOM 2806 C CB . LEU B 1 116 ? 11.928 -10.474 25.727 1.00 106.69 ? 116 LEU B CB 1 +ATOM 2807 C CG . LEU B 1 116 ? 13.359 -10.408 25.168 1.00 86.07 ? 116 LEU B CG 1 +ATOM 2808 C CD1 . LEU B 1 116 ? 14.121 -9.200 25.724 1.00 60.89 ? 116 LEU B CD1 1 +ATOM 2809 C CD2 . LEU B 1 116 ? 14.060 -11.711 25.481 1.00 72.45 ? 116 LEU B CD2 1 +ATOM 2810 N N . THR B 1 117 ? 8.689 -10.977 24.806 1.00 79.14 ? 117 THR B N 1 +ATOM 2811 C CA . THR B 1 117 ? 7.316 -11.240 25.231 1.00 82.53 ? 117 THR B CA 1 +ATOM 2812 C C . THR B 1 117 ? 7.444 -11.799 26.604 1.00 63.42 ? 117 THR B C 1 +ATOM 2813 O O . THR B 1 117 ? 8.274 -12.691 26.813 1.00 38.04 ? 117 THR B O 1 +ATOM 2814 C CB . THR B 1 117 ? 6.604 -12.287 24.330 1.00 95.51 ? 117 THR B CB 1 +ATOM 2815 O OG1 . THR B 1 117 ? 6.614 -11.844 22.972 1.00 106.89 ? 117 THR B OG1 1 +ATOM 2816 C CG2 . THR B 1 117 ? 5.161 -12.497 24.763 1.00 87.14 ? 117 THR B CG2 1 +ATOM 2817 N N . ALA B 1 118 ? 6.604 -11.302 27.519 1.00 52.22 ? 118 ALA B N 1 +ATOM 2818 C CA . ALA B 1 118 ? 6.739 -11.630 28.933 1.00 53.00 ? 118 ALA B CA 1 +ATOM 2819 C C . ALA B 1 118 ? 5.602 -12.436 29.480 1.00 57.11 ? 118 ALA B C 1 +ATOM 2820 O O . ALA B 1 118 ? 4.431 -12.171 29.165 1.00 51.38 ? 118 ALA B O 1 +ATOM 2821 C CB . ALA B 1 118 ? 6.862 -10.368 29.735 1.00 49.83 ? 118 ALA B CB 1 +ATOM 2822 N N . ALA B 1 119 ? 5.953 -13.364 30.367 1.00 62.72 ? 119 ALA B N 1 +ATOM 2823 C CA . ALA B 1 119 ? 4.995 -14.354 30.863 1.00 91.24 ? 119 ALA B CA 1 +ATOM 2824 C C . ALA B 1 119 ? 4.262 -13.843 32.095 1.00 108.97 ? 119 ALA B C 1 +ATOM 2825 O O . ALA B 1 119 ? 4.790 -12.985 32.814 1.00 79.06 ? 119 ALA B O 1 +ATOM 2826 C CB . ALA B 1 119 ? 5.712 -15.648 31.192 1.00 88.28 ? 119 ALA B CB 1 +ATOM 2827 N N . ASN B 1 120 ? 3.049 -14.362 32.341 1.00 122.76 ? 120 ASN B N 1 +ATOM 2828 C CA . ASN B 1 120 ? 2.317 -14.016 33.572 1.00 141.84 ? 120 ASN B CA 1 +ATOM 2829 C C . ASN B 1 120 ? 2.458 -15.053 34.673 1.00 134.19 ? 120 ASN B C 1 +ATOM 2830 O O . ASN B 1 120 ? 2.687 -14.726 35.840 1.00 111.55 ? 120 ASN B O 1 +ATOM 2831 C CB . ASN B 1 120 ? 0.828 -13.807 33.310 1.00 123.36 ? 120 ASN B CB 1 +ATOM 2832 C CG . ASN B 1 120 ? 0.057 -13.434 34.577 1.00 132.52 ? 120 ASN B CG 1 +ATOM 2833 O OD1 . ASN B 1 120 ? 0.563 -12.741 35.480 1.00 83.82 ? 120 ASN B OD1 1 +ATOM 2834 N ND2 . ASN B 1 120 ? -1.174 -13.931 34.664 1.00 168.72 ? 120 ASN B ND2 1 +ATOM 2835 N N . ILE B 1 121 ? 2.275 -16.311 34.307 1.00 145.27 ? 121 ILE B N 1 +ATOM 2836 C CA . ILE B 1 121 ? 2.547 -17.394 35.233 1.00 137.16 ? 121 ILE B CA 1 +ATOM 2837 C C . ILE B 1 121 ? 3.774 -18.127 34.732 1.00 118.72 ? 121 ILE B C 1 +ATOM 2838 O O . ILE B 1 121 ? 4.010 -18.252 33.539 1.00 121.34 ? 121 ILE B O 1 +ATOM 2839 C CB . ILE B 1 121 ? 1.352 -18.366 35.388 1.00 113.55 ? 121 ILE B CB 1 +ATOM 2840 C CG1 . ILE B 1 121 ? 1.185 -19.255 34.157 1.00 92.15 ? 121 ILE B CG1 1 +ATOM 2841 C CG2 . ILE B 1 121 ? 0.078 -17.588 35.682 1.00 122.27 ? 121 ILE B CG2 1 +ATOM 2842 C CD1 . ILE B 1 121 ? 1.536 -20.690 34.410 1.00 82.58 ? 121 ILE B CD1 1 +ATOM 2843 N N . MET B 1 122 ? 4.622 -18.515 35.653 1.00 104.72 ? 122 MET B N 1 +ATOM 2844 C CA . MET B 1 122 ? 5.661 -19.407 35.283 1.00 90.36 ? 122 MET B CA 1 +ATOM 2845 C C . MET B 1 122 ? 5.452 -20.686 36.081 1.00 77.96 ? 122 MET B C 1 +ATOM 2846 O O . MET B 1 122 ? 5.102 -20.651 37.256 1.00 103.02 ? 122 MET B O 1 +ATOM 2847 C CB . MET B 1 122 ? 7.041 -18.734 35.445 1.00 78.71 ? 122 MET B CB 1 +ATOM 2848 C CG . MET B 1 122 ? 7.365 -18.191 36.821 1.00 96.57 ? 122 MET B CG 1 +ATOM 2849 S SD . MET B 1 122 ? 9.164 -18.173 37.067 1.00 123.98 ? 122 MET B SD 1 +ATOM 2850 C CE . MET B 1 122 ? 9.240 -18.787 38.768 1.00 108.37 ? 122 MET B CE 1 +ATOM 2851 N N . VAL B 1 123 ? 5.729 -21.817 35.449 1.00 60.98 ? 123 VAL B N 1 +ATOM 2852 C CA . VAL B 1 123 ? 5.680 -23.109 36.129 1.00 56.15 ? 123 VAL B CA 1 +ATOM 2853 C C . VAL B 1 123 ? 7.034 -23.806 36.228 1.00 60.29 ? 123 VAL B C 1 +ATOM 2854 O O . VAL B 1 123 ? 7.740 -23.954 35.249 1.00 77.59 ? 123 VAL B O 1 +ATOM 2855 C CB . VAL B 1 123 ? 4.739 -24.067 35.411 1.00 47.67 ? 123 VAL B CB 1 +ATOM 2856 C CG1 . VAL B 1 123 ? 4.915 -23.958 33.916 1.00 48.19 ? 123 VAL B CG1 1 +ATOM 2857 C CG2 . VAL B 1 123 ? 4.922 -25.506 35.897 1.00 44.45 ? 123 VAL B CG2 1 +ATOM 2858 N N . GLU B 1 124 ? 7.411 -24.180 37.440 1.00 67.33 ? 124 GLU B N 1 +ATOM 2859 C CA . GLU B 1 124 ? 8.619 -24.942 37.650 1.00 69.92 ? 124 GLU B CA 1 +ATOM 2860 C C . GLU B 1 124 ? 8.304 -26.174 38.450 1.00 76.82 ? 124 GLU B C 1 +ATOM 2861 O O . GLU B 1 124 ? 7.238 -26.307 39.028 1.00 106.22 ? 124 GLU B O 1 +ATOM 2862 C CB . GLU B 1 124 ? 9.712 -24.111 38.347 1.00 63.01 ? 124 GLU B CB 1 +ATOM 2863 C CG . GLU B 1 124 ? 9.220 -23.018 39.274 1.00 57.83 ? 124 GLU B CG 1 +ATOM 2864 C CD . GLU B 1 124 ? 10.285 -21.995 39.546 1.00 64.49 ? 124 GLU B CD 1 +ATOM 2865 O OE1 . GLU B 1 124 ? 11.103 -21.707 38.633 1.00 71.53 ? 124 GLU B OE1 1 +ATOM 2866 O OE2 . GLU B 1 124 ? 10.374 -21.538 40.704 1.00 71.48 ? 124 GLU B OE2 1 +ATOM 2867 N N . GLY B 1 125 ? 9.283 -27.059 38.521 1.00 97.43 ? 125 GLY B N 1 +ATOM 2868 C CA . GLY B 1 125 ? 9.110 -28.319 39.209 1.00 81.29 ? 125 GLY B CA 1 +ATOM 2869 C C . GLY B 1 125 ? 10.425 -29.098 39.283 1.00 61.48 ? 125 GLY B C 1 +ATOM 2870 O O . GLY B 1 125 ? 11.503 -28.528 39.188 1.00 49.89 ? 125 GLY B O 1 +ATOM 2871 N N . SER B 1 126 ? 10.321 -30.395 39.534 1.00 44.19 ? 126 SER B N 1 +ATOM 2872 C CA . SER B 1 126 ? 11.484 -31.206 39.853 1.00 46.47 ? 126 SER B CA 1 +ATOM 2873 C C . SER B 1 126 ? 11.155 -32.648 39.733 1.00 50.74 ? 126 SER B C 1 +ATOM 2874 O O . SER B 1 126 ? 9.987 -33.039 39.885 1.00 95.98 ? 126 SER B O 1 +ATOM 2875 C CB . SER B 1 126 ? 11.940 -30.992 41.297 1.00 58.21 ? 126 SER B CB 1 +ATOM 2876 O OG . SER B 1 126 ? 11.671 -29.669 41.795 1.00 79.09 ? 126 SER B OG 1 +ATOM 2877 N N . ILE B 1 127 ? 12.112 -33.426 39.283 1.00 65.32 ? 127 ILE B N 1 +ATOM 2878 C CA . ILE B 1 127 ? 11.918 -34.879 39.305 1.00 91.89 ? 127 ILE B CA 1 +ATOM 2879 C C . ILE B 1 127 ? 12.193 -35.353 40.722 1.00 99.37 ? 127 ILE B C 1 +ATOM 2880 O O . ILE B 1 127 ? 13.351 -35.283 41.147 1.00 138.60 ? 127 ILE B O 1 +ATOM 2881 C CB . ILE B 1 127 ? 12.847 -35.617 38.315 1.00 114.14 ? 127 ILE B CB 1 +ATOM 2882 C CG1 . ILE B 1 127 ? 12.453 -35.315 36.858 1.00 118.92 ? 127 ILE B CG1 1 +ATOM 2883 C CG2 . ILE B 1 127 ? 12.806 -37.116 38.576 1.00 85.11 ? 127 ILE B CG2 1 +ATOM 2884 C CD1 . ILE B 1 127 ? 13.618 -35.352 35.883 1.00 135.71 ? 127 ILE B CD1 1 +ATOM 2885 N N . ILE B 1 128 ? 11.130 -35.675 41.460 1.00 75.49 ? 128 ILE B N 1 +ATOM 2886 C CA . ILE B 1 128 ? 11.204 -35.893 42.918 1.00 79.46 ? 128 ILE B CA 1 +ATOM 2887 C C . ILE B 1 128 ? 11.322 -37.254 43.484 1.00 81.19 ? 128 ILE B C 1 +ATOM 2888 O O . ILE B 1 128 ? 10.927 -37.467 44.665 1.00 131.64 ? 128 ILE B O 1 +ATOM 2889 C CB . ILE B 1 128 ? 10.018 -35.263 43.664 1.00 80.11 ? 128 ILE B CB 1 +ATOM 2890 C CG1 . ILE B 1 128 ? 8.701 -35.639 43.000 1.00 100.18 ? 128 ILE B CG1 1 +ATOM 2891 C CG2 . ILE B 1 128 ? 10.105 -33.752 43.644 1.00 96.54 ? 128 ILE B CG2 1 +ATOM 2892 C CD1 . ILE B 1 128 ? 7.539 -35.616 43.973 1.00 128.54 ? 128 ILE B CD1 1 +ATOM 2893 N N . GLY B 1 129 ? 12.162 -38.036 42.841 1.00 84.51 ? 129 GLY B N 1 +ATOM 2894 C CA . GLY B 1 129 ? 12.443 -39.412 43.262 1.00 82.87 ? 129 GLY B CA 1 +ATOM 2895 C C . GLY B 1 129 ? 12.432 -40.397 42.122 1.00 84.35 ? 129 GLY B C 1 +ATOM 2896 O O . GLY B 1 129 ? 11.696 -40.256 41.150 1.00 97.53 ? 129 GLY B O 1 +ATOM 2897 N N . TYR B 1 130 ? 13.391 -41.309 42.186 1.00 96.69 ? 130 TYR B N 1 +ATOM 2898 C CA . TYR B 1 130 ? 13.363 -42.513 41.385 1.00 88.26 ? 130 TYR B CA 1 +ATOM 2899 C C . TYR B 1 130 ? 13.837 -43.602 42.324 1.00 115.21 ? 130 TYR B C 1 +ATOM 2900 O O . TYR B 1 130 ? 15.003 -43.641 42.692 1.00 132.06 ? 130 TYR B O 1 +ATOM 2901 C CB . TYR B 1 130 ? 14.292 -42.403 40.174 1.00 87.95 ? 130 TYR B CB 1 +ATOM 2902 C CG . TYR B 1 130 ? 14.395 -43.670 39.348 1.00 76.90 ? 130 TYR B CG 1 +ATOM 2903 C CD1 . TYR B 1 130 ? 15.100 -44.769 39.818 1.00 70.73 ? 130 TYR B CD1 1 +ATOM 2904 C CD2 . TYR B 1 130 ? 13.854 -43.728 38.053 1.00 84.66 ? 130 TYR B CD2 1 +ATOM 2905 C CE1 . TYR B 1 130 ? 15.276 -45.887 39.027 1.00 87.26 ? 130 TYR B CE1 1 +ATOM 2906 C CE2 . TYR B 1 130 ? 14.040 -44.834 37.250 1.00 92.91 ? 130 TYR B CE2 1 +ATOM 2907 C CZ . TYR B 1 130 ? 14.730 -45.917 37.746 1.00 100.57 ? 130 TYR B CZ 1 +ATOM 2908 O OH . TYR B 1 130 ? 14.877 -47.025 36.947 1.00 131.12 ? 130 TYR B OH 1 +ATOM 2909 N N . GLU B 1 131 ? 12.908 -44.422 42.785 1.00 131.29 ? 131 GLU B N 1 +ATOM 2910 C CA . GLU B 1 131 ? 13.276 -45.617 43.560 1.00 145.74 ? 131 GLU B CA 1 +ATOM 2911 C C . GLU B 1 131 ? 13.293 -46.809 42.594 1.00 123.90 ? 131 GLU B C 1 +ATOM 2912 O O . GLU B 1 131 ? 12.573 -46.813 41.583 1.00 130.40 ? 131 GLU B O 1 +ATOM 2913 C CB . GLU B 1 131 ? 12.371 -45.870 44.799 1.00 186.31 ? 131 GLU B CB 1 +ATOM 2914 C CG . GLU B 1 131 ? 12.873 -45.117 46.097 1.00 196.20 ? 131 GLU B CG 1 +ATOM 2915 C CD . GLU B 1 131 ? 13.469 -43.719 45.799 1.00 203.06 ? 131 GLU B CD 1 +ATOM 2916 O OE1 . GLU B 1 131 ? 12.810 -42.808 45.258 1.00 167.19 ? 131 GLU B OE1 1 +ATOM 2917 O OE2 . GLU B 1 131 ? 14.607 -43.466 46.196 1.00 170.29 ? 131 GLU B OE2 1 +ATOM 2918 N N . SER B 1 132 ? 14.194 -47.755 42.837 1.00 106.61 ? 132 SER B N 1 +ATOM 2919 C CA . SER B 1 132 ? 14.454 -48.811 41.865 1.00 98.04 ? 132 SER B CA 1 +ATOM 2920 C C . SER B 1 132 ? 14.140 -50.167 42.464 1.00 104.17 ? 132 SER B C 1 +ATOM 2921 O O . SER B 1 132 ? 14.437 -50.426 43.633 1.00 120.50 ? 132 SER B O 1 +ATOM 2922 C CB . SER B 1 132 ? 15.906 -48.759 41.374 1.00 93.20 ? 132 SER B CB 1 +ATOM 2923 O OG . SER B 1 132 ? 16.648 -49.873 41.830 1.00 82.26 ? 132 SER B OG 1 +ATOM 2924 N N . ASN B 1 133 ? 13.576 -51.045 41.643 1.00 115.64 ? 133 ASN B N 1 +ATOM 2925 C CA . ASN B 1 133 ? 13.035 -52.328 42.116 1.00 130.57 ? 133 ASN B CA 1 +ATOM 2926 C C . ASN B 1 133 ? 12.143 -52.148 43.335 1.00 120.84 ? 133 ASN B C 1 +ATOM 2927 O O . ASN B 1 133 ? 12.383 -52.734 44.389 1.00 120.36 ? 133 ASN B O 1 +ATOM 2928 C CB . ASN B 1 133 ? 14.148 -53.330 42.432 1.00 120.62 ? 133 ASN B CB 1 +ATOM 2929 C CG . ASN B 1 133 ? 15.013 -53.628 41.232 1.00 126.41 ? 133 ASN B CG 1 +ATOM 2930 O OD1 . ASN B 1 133 ? 14.561 -53.576 40.073 1.00 132.27 ? 133 ASN B OD1 1 +ATOM 2931 N ND2 . ASN B 1 133 ? 16.272 -53.923 41.487 1.00 155.15 ? 133 ASN B ND2 1 +ATOM 2932 N N . VAL B 1 134 ? 11.142 -51.294 43.173 1.00 115.10 ? 134 VAL B N 1 +ATOM 2933 C CA . VAL B 1 134 ? 10.195 -51.003 44.227 1.00 114.84 ? 134 VAL B CA 1 +ATOM 2934 C C . VAL B 1 134 ? 9.403 -52.284 44.452 1.00 114.29 ? 134 VAL B C 1 +ATOM 2935 O O . VAL B 1 134 ? 9.031 -52.609 45.585 1.00 115.40 ? 134 VAL B O 1 +ATOM 2936 C CB . VAL B 1 134 ? 9.270 -49.817 43.836 1.00 124.06 ? 134 VAL B CB 1 +ATOM 2937 C CG1 . VAL B 1 134 ? 8.320 -49.469 44.968 1.00 125.33 ? 134 VAL B CG1 1 +ATOM 2938 C CG2 . VAL B 1 134 ? 10.099 -48.594 43.468 1.00 116.62 ? 134 VAL B CG2 1 +ATOM 2939 N N . LYS B 1 135 ? 9.148 -53.012 43.363 1.00 110.38 ? 135 LYS B N 1 +ATOM 2940 C CA . LYS B 1 135 ? 8.702 -54.401 43.465 1.00 104.37 ? 135 LYS B CA 1 +ATOM 2941 C C . LYS B 1 135 ? 9.439 -55.296 42.493 1.00 101.11 ? 135 LYS B C 1 +ATOM 2942 O O . LYS B 1 135 ? 9.966 -54.834 41.467 1.00 140.52 ? 135 LYS B O 1 +ATOM 2943 C CB . LYS B 1 135 ? 7.198 -54.505 43.201 1.00 121.03 ? 135 LYS B CB 1 +ATOM 2944 C CG . LYS B 1 135 ? 6.348 -53.753 44.216 1.00 143.47 ? 135 LYS B CG 1 +ATOM 2945 C CD . LYS B 1 135 ? 4.880 -53.803 43.833 1.00 142.76 ? 135 LYS B CD 1 +ATOM 2946 C CE . LYS B 1 135 ? 4.018 -53.045 44.821 1.00 131.46 ? 135 LYS B CE 1 +ATOM 2947 N NZ . LYS B 1 135 ? 2.610 -53.504 44.731 1.00 131.03 ? 135 LYS B NZ 1 +ATOM 2948 N N . SER B 1 136 ? 9.441 -56.590 42.794 1.00 111.05 ? 136 SER B N 1 +ATOM 2949 C CA . SER B 1 136 ? 10.081 -57.580 41.925 1.00 131.16 ? 136 SER B CA 1 +ATOM 2950 C C . SER B 1 136 ? 9.639 -59.006 42.238 1.00 118.20 ? 136 SER B C 1 +ATOM 2951 O O . SER B 1 136 ? 9.123 -59.275 43.319 1.00 99.56 ? 136 SER B O 1 +ATOM 2952 C CB . SER B 1 136 ? 11.597 -57.495 42.043 1.00 144.75 ? 136 SER B CB 1 +ATOM 2953 O OG . SER B 1 136 ? 12.153 -58.758 42.379 1.00 127.71 ? 136 SER B OG 1 +ATOM 2954 N N . GLY B 1 137 ? 9.755 -59.888 41.245 1.00 125.60 ? 137 GLY B N 1 +ATOM 2955 C CA . GLY B 1 137 ? 9.324 -61.276 41.406 1.00 131.98 ? 137 GLY B CA 1 +ATOM 2956 C C . GLY B 1 137 ? 9.765 -62.188 40.280 1.00 125.14 ? 137 GLY B C 1 +ATOM 2957 O O . GLY B 1 137 ? 10.370 -61.735 39.305 1.00 80.59 ? 137 GLY B O 1 +ATOM 2958 N N . GLY B 1 138 ? 9.488 -63.480 40.435 1.00 125.41 ? 138 GLY B N 1 +ATOM 2959 C CA . GLY B 1 138 ? 9.908 -64.466 39.450 1.00 131.48 ? 138 GLY B CA 1 +ATOM 2960 C C . GLY B 1 138 ? 9.288 -65.828 39.660 1.00 101.90 ? 138 GLY B C 1 +ATOM 2961 O O . GLY B 1 138 ? 9.042 -66.243 40.787 1.00 94.64 ? 138 GLY B O 1 +ATOM 2962 N N . VAL B 1 139 ? 9.007 -66.505 38.556 1.00 100.16 ? 139 VAL B N 1 +ATOM 2963 C CA . VAL B 1 139 ? 8.420 -67.838 38.587 1.00 101.63 ? 139 VAL B CA 1 +ATOM 2964 C C . VAL B 1 139 ? 9.051 -68.693 37.501 1.00 115.59 ? 139 VAL B C 1 +ATOM 2965 O O . VAL B 1 139 ? 9.042 -68.331 36.317 1.00 111.57 ? 139 VAL B O 1 +ATOM 2966 C CB . VAL B 1 139 ? 6.887 -67.820 38.356 1.00 91.16 ? 139 VAL B CB 1 +ATOM 2967 C CG1 . VAL B 1 139 ? 6.356 -69.236 38.268 1.00 82.29 ? 139 VAL B CG1 1 +ATOM 2968 C CG2 . VAL B 1 139 ? 6.172 -67.057 39.466 1.00 93.94 ? 139 VAL B CG2 1 +ATOM 2969 N N . GLY B 1 140 ? 9.563 -69.850 37.903 1.00 130.58 ? 140 GLY B N 1 +ATOM 2970 C CA . GLY B 1 140 ? 10.213 -70.763 36.971 1.00 137.10 ? 140 GLY B CA 1 +ATOM 2971 C C . GLY B 1 140 ? 10.088 -72.219 37.363 1.00 125.39 ? 140 GLY B C 1 +ATOM 2972 O O . GLY B 1 140 ? 10.097 -72.558 38.552 1.00 145.86 ? 140 GLY B O 1 +ATOM 2973 N N . ALA B 1 141 ? 10.022 -73.090 36.362 1.00 110.48 ? 141 ALA B N 1 +ATOM 2974 C CA . ALA B 1 141 ? 10.057 -74.523 36.609 1.00 104.10 ? 141 ALA B CA 1 +ATOM 2975 C C . ALA B 1 141 ? 10.847 -75.269 35.543 1.00 114.55 ? 141 ALA B C 1 +ATOM 2976 O O . ALA B 1 141 ? 10.798 -74.947 34.357 1.00 113.97 ? 141 ALA B O 1 +ATOM 2977 C CB . ALA B 1 141 ? 8.650 -75.078 36.716 1.00 103.73 ? 141 ALA B CB 1 +ATOM 2978 N N . ARG B 1 142 ? 11.614 -76.251 35.989 1.00 164.00 ? 142 ARG B N 1 +ATOM 2979 C CA . ARG B 1 142 ? 12.274 -77.155 35.078 1.00 192.46 ? 142 ARG B CA 1 +ATOM 2980 C C . ARG B 1 142 ? 11.964 -78.578 35.509 1.00 192.24 ? 142 ARG B C 1 +ATOM 2981 O O . ARG B 1 142 ? 11.871 -78.865 36.705 1.00 206.20 ? 142 ARG B O 1 +ATOM 2982 C CB . ARG B 1 142 ? 13.792 -76.906 35.028 1.00 202.64 ? 142 ARG B CB 1 +ATOM 2983 C CG . ARG B 1 142 ? 14.502 -77.785 34.003 1.00 201.67 ? 142 ARG B CG 1 +ATOM 2984 C CD . ARG B 1 142 ? 15.557 -77.031 33.227 1.00 180.69 ? 142 ARG B CD 1 +ATOM 2985 N NE . ARG B 1 142 ? 16.753 -76.898 34.046 1.00 183.80 ? 142 ARG B NE 1 +ATOM 2986 C CZ . ARG B 1 142 ? 17.635 -75.912 33.931 1.00 195.19 ? 142 ARG B CZ 1 +ATOM 2987 N NH1 . ARG B 1 142 ? 17.519 -74.997 32.972 1.00 187.85 ? 142 ARG B NH1 1 +ATOM 2988 N NH2 . ARG B 1 142 ? 18.685 -75.870 34.745 1.00 211.18 ? 142 ARG B NH2 1 +ATOM 2989 N N . TYR B 1 143 ? 11.817 -79.456 34.523 1.00 183.53 ? 143 TYR B N 1 +ATOM 2990 C CA . TYR B 1 143 ? 11.461 -80.840 34.744 1.00 177.37 ? 143 TYR B CA 1 +ATOM 2991 C C . TYR B 1 143 ? 12.416 -81.761 33.959 1.00 154.46 ? 143 TYR B C 1 +ATOM 2992 O O . TYR B 1 143 ? 12.074 -82.299 32.907 1.00 101.97 ? 143 TYR B O 1 +ATOM 2993 C CB . TYR B 1 143 ? 9.993 -81.080 34.336 1.00 189.27 ? 143 TYR B CB 1 +ATOM 2994 C CG . TYR B 1 143 ? 9.541 -82.472 34.681 1.00 204.03 ? 143 TYR B CG 1 +ATOM 2995 C CD1 . TYR B 1 143 ? 9.429 -82.870 36.012 1.00 201.94 ? 143 TYR B CD1 1 +ATOM 2996 C CD2 . TYR B 1 143 ? 9.396 -83.431 33.697 1.00 198.47 ? 143 TYR B CD2 1 +ATOM 2997 C CE1 . TYR B 1 143 ? 9.158 -84.178 36.362 1.00 178.00 ? 143 TYR B CE1 1 +ATOM 2998 C CE2 . TYR B 1 143 ? 9.110 -84.743 34.035 1.00 202.56 ? 143 TYR B CE2 1 +ATOM 2999 C CZ . TYR B 1 143 ? 8.997 -85.110 35.367 1.00 177.48 ? 143 TYR B CZ 1 +ATOM 3000 O OH . TYR B 1 143 ? 8.724 -86.409 35.700 1.00 143.57 ? 143 TYR B OH 1 +ATOM 3001 N N . GLY B 1 145 ? 15.182 -82.576 29.495 1.00 112.67 ? 145 GLY B N 1 +ATOM 3002 C CA . GLY B 1 145 ? 14.781 -81.770 30.646 1.00 134.90 ? 145 GLY B CA 1 +ATOM 3003 C C . GLY B 1 145 ? 14.350 -80.377 30.206 1.00 172.93 ? 145 GLY B C 1 +ATOM 3004 O O . GLY B 1 145 ? 15.107 -79.613 29.600 1.00 177.44 ? 145 GLY B O 1 +ATOM 3005 N N . ILE B 1 146 ? 13.104 -80.039 30.533 1.00 213.51 ? 146 ILE B N 1 +ATOM 3006 C CA . ILE B 1 146 ? 12.405 -78.911 29.893 1.00 188.90 ? 146 ILE B CA 1 +ATOM 3007 C C . ILE B 1 146 ? 12.067 -77.851 30.939 1.00 158.99 ? 146 ILE B C 1 +ATOM 3008 O O . ILE B 1 146 ? 11.633 -78.189 32.041 1.00 129.28 ? 146 ILE B O 1 +ATOM 3009 C CB . ILE B 1 146 ? 11.100 -79.367 29.185 1.00 168.03 ? 146 ILE B CB 1 +ATOM 3010 C CG1 . ILE B 1 146 ? 11.298 -80.733 28.507 1.00 174.66 ? 146 ILE B CG1 1 +ATOM 3011 C CG2 . ILE B 1 146 ? 10.653 -78.327 28.165 1.00 129.33 ? 146 ILE B CG2 1 +ATOM 3012 C CD1 . ILE B 1 146 ? 10.837 -81.924 29.330 1.00 154.15 ? 146 ILE B CD1 1 +ATOM 3013 N N . GLY B 1 147 ? 12.281 -76.578 30.610 1.00 141.52 ? 147 GLY B N 1 +ATOM 3014 C CA . GLY B 1 147 ? 12.081 -75.513 31.591 1.00 145.28 ? 147 GLY B CA 1 +ATOM 3015 C C . GLY B 1 147 ? 11.728 -74.138 31.049 1.00 133.47 ? 147 GLY B C 1 +ATOM 3016 O O . GLY B 1 147 ? 11.988 -73.815 29.891 1.00 98.26 ? 147 GLY B O 1 +ATOM 3017 N N . ALA B 1 148 ? 11.097 -73.338 31.901 1.00 128.95 ? 148 ALA B N 1 +ATOM 3018 C CA . ALA B 1 148 ? 10.822 -71.952 31.584 1.00 118.03 ? 148 ALA B CA 1 +ATOM 3019 C C . ALA B 1 148 ? 10.816 -71.119 32.859 1.00 113.70 ? 148 ALA B C 1 +ATOM 3020 O O . ALA B 1 148 ? 10.772 -71.649 33.972 1.00 79.81 ? 148 ALA B O 1 +ATOM 3021 C CB . ALA B 1 148 ? 9.489 -71.808 30.846 1.00 116.47 ? 148 ALA B CB 1 +ATOM 3022 N N . ASP B 1 149 ? 10.857 -69.804 32.686 1.00 138.81 ? 149 ASP B N 1 +ATOM 3023 C CA . ASP B 1 149 ? 10.804 -68.885 33.818 1.00 145.33 ? 149 ASP B CA 1 +ATOM 3024 C C . ASP B 1 149 ? 10.567 -67.454 33.357 1.00 152.11 ? 149 ASP B C 1 +ATOM 3025 O O . ASP B 1 149 ? 10.980 -67.071 32.254 1.00 176.93 ? 149 ASP B O 1 +ATOM 3026 C CB . ASP B 1 149 ? 12.099 -68.963 34.638 1.00 163.37 ? 149 ASP B CB 1 +ATOM 3027 C CG . ASP B 1 149 ? 13.221 -68.171 34.023 1.00 177.91 ? 149 ASP B CG 1 +ATOM 3028 O OD1 . ASP B 1 149 ? 13.796 -68.656 33.028 1.00 219.24 ? 149 ASP B OD1 1 +ATOM 3029 O OD2 . ASP B 1 149 ? 13.551 -67.103 34.563 1.00 153.69 ? 149 ASP B OD2 1 +ATOM 3030 N N . THR B 1 150 ? 9.875 -66.679 34.182 1.00 147.04 ? 150 THR B N 1 +ATOM 3031 C CA . THR B 1 150 ? 9.848 -65.231 34.004 1.00 141.07 ? 150 THR B CA 1 +ATOM 3032 C C . THR B 1 150 ? 10.337 -64.551 35.269 1.00 128.60 ? 150 THR B C 1 +ATOM 3033 O O . THR B 1 150 ? 10.265 -65.109 36.360 1.00 128.50 ? 150 THR B O 1 +ATOM 3034 C CB . THR B 1 150 ? 8.446 -64.696 33.655 1.00 144.75 ? 150 THR B CB 1 +ATOM 3035 O OG1 . THR B 1 150 ? 7.520 -65.043 34.690 1.00 164.79 ? 150 THR B OG1 1 +ATOM 3036 C CG2 . THR B 1 150 ? 7.960 -65.263 32.330 1.00 155.37 ? 150 THR B CG2 1 +ATOM 3037 N N . GLN B 1 151 ? 10.880 -63.357 35.105 1.00 135.76 ? 151 GLN B N 1 +ATOM 3038 C CA . GLN B 1 151 ? 11.217 -62.506 36.256 1.00 126.64 ? 151 GLN B CA 1 +ATOM 3039 C C . GLN B 1 151 ? 10.838 -61.063 35.910 1.00 115.58 ? 151 GLN B C 1 +ATOM 3040 O O . GLN B 1 151 ? 10.834 -60.667 34.736 1.00 106.25 ? 151 GLN B O 1 +ATOM 3041 C CB . GLN B 1 151 ? 12.688 -62.663 36.733 1.00 138.51 ? 151 GLN B CB 1 +ATOM 3042 C CG . GLN B 1 151 ? 13.734 -62.095 35.795 1.00 165.97 ? 151 GLN B CG 1 +ATOM 3043 C CD . GLN B 1 151 ? 15.074 -61.841 36.477 1.00 168.36 ? 151 GLN B CD 1 +ATOM 3044 O OE1 . GLN B 1 151 ? 15.510 -62.630 37.302 1.00 159.71 ? 151 GLN B OE1 1 +ATOM 3045 N NE2 . GLN B 1 151 ? 15.729 -60.729 36.132 1.00 175.37 ? 151 GLN B NE2 1 +ATOM 3046 N N . TYR B 1 152 ? 10.387 -60.318 36.906 1.00 92.16 ? 152 TYR B N 1 +ATOM 3047 C CA . TYR B 1 152 ? 9.965 -58.948 36.667 1.00 94.47 ? 152 TYR B CA 1 +ATOM 3048 C C . TYR B 1 152 ? 10.429 -58.029 37.762 1.00 103.55 ? 152 TYR B C 1 +ATOM 3049 O O . TYR B 1 152 ? 10.552 -58.432 38.918 1.00 96.14 ? 152 TYR B O 1 +ATOM 3050 C CB . TYR B 1 152 ? 8.446 -58.843 36.514 1.00 94.57 ? 152 TYR B CB 1 +ATOM 3051 C CG . TYR B 1 152 ? 7.679 -58.261 37.693 1.00 81.90 ? 152 TYR B CG 1 +ATOM 3052 C CD1 . TYR B 1 152 ? 7.634 -58.914 38.916 1.00 79.03 ? 152 TYR B CD1 1 +ATOM 3053 C CD2 . TYR B 1 152 ? 6.880 -57.150 37.528 1.00 87.29 ? 152 TYR B CD2 1 +ATOM 3054 C CE1 . TYR B 1 152 ? 6.860 -58.438 39.965 1.00 90.20 ? 152 TYR B CE1 1 +ATOM 3055 C CE2 . TYR B 1 152 ? 6.093 -56.669 38.563 1.00 105.72 ? 152 TYR B CE2 1 +ATOM 3056 C CZ . TYR B 1 152 ? 6.091 -57.306 39.784 1.00 107.43 ? 152 TYR B CZ 1 +ATOM 3057 O OH . TYR B 1 152 ? 5.310 -56.823 40.818 1.00 123.67 ? 152 TYR B OH 1 +ATOM 3058 N N . GLN B 1 153 ? 10.712 -56.791 37.383 1.00 109.15 ? 153 GLN B N 1 +ATOM 3059 C CA . GLN B 1 153 ? 10.997 -55.759 38.355 1.00 104.99 ? 153 GLN B CA 1 +ATOM 3060 C C . GLN B 1 153 ? 10.270 -54.495 37.957 1.00 95.36 ? 153 GLN B C 1 +ATOM 3061 O O . GLN B 1 153 ? 9.997 -54.262 36.773 1.00 123.59 ? 153 GLN B O 1 +ATOM 3062 C CB . GLN B 1 153 ? 12.514 -55.524 38.439 1.00 153.75 ? 153 GLN B CB 1 +ATOM 3063 C CG . GLN B 1 153 ? 13.330 -56.714 38.982 1.00 193.69 ? 153 GLN B CG 1 +ATOM 3064 C CD . GLN B 1 153 ? 14.851 -56.482 38.879 1.00 222.34 ? 153 GLN B CD 1 +ATOM 3065 O OE1 . GLN B 1 153 ? 15.316 -55.616 38.122 1.00 235.72 ? 153 GLN B OE1 1 +ATOM 3066 N NE2 . GLN B 1 153 ? 15.619 -57.186 39.707 1.00 226.95 ? 153 GLN B NE2 1 +ATOM 3067 N N . LEU B 1 154 ? 9.992 -53.645 38.930 1.00 91.20 ? 154 LEU B N 1 +ATOM 3068 C CA . LEU B 1 154 ? 9.445 -52.327 38.617 1.00 109.93 ? 154 LEU B CA 1 +ATOM 3069 C C . LEU B 1 154 ? 9.930 -51.218 39.544 1.00 107.02 ? 154 LEU B C 1 +ATOM 3070 O O . LEU B 1 154 ? 10.120 -51.429 40.757 1.00 85.48 ? 154 LEU B O 1 +ATOM 3071 C CB . LEU B 1 154 ? 7.914 -52.362 38.604 1.00 100.44 ? 154 LEU B CB 1 +ATOM 3072 C CG . LEU B 1 154 ? 7.243 -52.500 39.972 1.00 106.35 ? 154 LEU B CG 1 +ATOM 3073 C CD1 . LEU B 1 154 ? 6.853 -51.150 40.542 1.00 92.60 ? 154 LEU B CD1 1 +ATOM 3074 C CD2 . LEU B 1 154 ? 6.036 -53.414 39.842 1.00 135.23 ? 154 LEU B CD2 1 +ATOM 3075 N N . ASP B 1 155 ? 10.036 -50.026 38.951 1.00 108.62 ? 155 ASP B N 1 +ATOM 3076 C CA . ASP B 1 155 ? 10.677 -48.869 39.557 1.00 110.30 ? 155 ASP B CA 1 +ATOM 3077 C C . ASP B 1 155 ? 9.655 -47.745 39.622 1.00 103.21 ? 155 ASP B C 1 +ATOM 3078 O O . ASP B 1 155 ? 8.677 -47.746 38.887 1.00 83.02 ? 155 ASP B O 1 +ATOM 3079 C CB . ASP B 1 155 ? 11.891 -48.440 38.713 1.00 114.11 ? 155 ASP B CB 1 +ATOM 3080 C CG . ASP B 1 155 ? 12.782 -49.615 38.335 1.00 139.76 ? 155 ASP B CG 1 +ATOM 3081 O OD1 . ASP B 1 155 ? 12.444 -50.346 37.384 1.00 153.88 ? 155 ASP B OD1 1 +ATOM 3082 O OD2 . ASP B 1 155 ? 13.828 -49.815 38.982 1.00 137.26 ? 155 ASP B OD2 1 +ATOM 3083 N N . GLN B 1 156 ? 9.906 -46.753 40.468 1.00 103.19 ? 156 GLN B N 1 +ATOM 3084 C CA . GLN B 1 156 ? 9.019 -45.590 40.553 1.00 86.84 ? 156 GLN B CA 1 +ATOM 3085 C C . GLN B 1 156 ? 9.694 -44.305 40.042 1.00 83.76 ? 156 GLN B C 1 +ATOM 3086 O O . GLN B 1 156 ? 10.921 -44.165 40.117 1.00 109.75 ? 156 GLN B O 1 +ATOM 3087 C CB . GLN B 1 156 ? 8.532 -45.445 41.993 1.00 82.36 ? 156 GLN B CB 1 +ATOM 3088 C CG . GLN B 1 156 ? 7.380 -44.478 42.168 1.00 84.70 ? 156 GLN B CG 1 +ATOM 3089 C CD . GLN B 1 156 ? 6.611 -44.710 43.459 1.00 89.58 ? 156 GLN B CD 1 +ATOM 3090 O OE1 . GLN B 1 156 ? 7.034 -45.487 44.331 1.00 95.18 ? 156 GLN B OE1 1 +ATOM 3091 N NE2 . GLN B 1 156 ? 5.468 -44.041 43.586 1.00 71.65 ? 156 GLN B NE2 1 +ATOM 3092 N N . ILE B 1 157 ? 8.888 -43.349 39.594 1.00 69.63 ? 157 ILE B N 1 +ATOM 3093 C CA . ILE B 1 157 ? 9.386 -41.998 39.270 1.00 67.46 ? 157 ILE B CA 1 +ATOM 3094 C C . ILE B 1 157 ? 8.288 -40.939 39.517 1.00 50.92 ? 157 ILE B C 1 +ATOM 3095 O O . ILE B 1 157 ? 7.104 -41.238 39.409 1.00 40.93 ? 157 ILE B O 1 +ATOM 3096 C CB . ILE B 1 157 ? 9.801 -41.952 37.811 1.00 60.79 ? 157 ILE B CB 1 +ATOM 3097 C CG1 . ILE B 1 157 ? 10.810 -40.861 37.576 1.00 61.21 ? 157 ILE B CG1 1 +ATOM 3098 C CG2 . ILE B 1 157 ? 8.582 -41.740 36.940 1.00 62.03 ? 157 ILE B CG2 1 +ATOM 3099 C CD1 . ILE B 1 157 ? 11.409 -40.872 36.181 1.00 60.42 ? 157 ILE B CD1 1 +ATOM 3100 N N . ALA B 1 158 ? 8.665 -39.822 40.114 1.00 47.04 ? 158 ALA B N 1 +ATOM 3101 C CA . ALA B 1 158 ? 7.670 -38.873 40.535 1.00 66.02 ? 158 ALA B CA 1 +ATOM 3102 C C . ALA B 1 158 ? 8.101 -37.508 40.099 1.00 90.24 ? 158 ALA B C 1 +ATOM 3103 O O . ALA B 1 158 ? 9.300 -37.216 40.018 1.00 73.03 ? 158 ALA B O 1 +ATOM 3104 C CB . ALA B 1 158 ? 7.406 -38.907 42.049 1.00 64.82 ? 158 ALA B CB 1 +ATOM 3105 N N . VAL B 1 159 ? 7.109 -36.662 39.839 1.00 100.64 ? 159 VAL B N 1 +ATOM 3106 C CA . VAL B 1 159 ? 7.368 -35.345 39.315 1.00 116.86 ? 159 VAL B CA 1 +ATOM 3107 C C . VAL B 1 159 ? 6.488 -34.307 39.999 1.00 100.20 ? 159 VAL B C 1 +ATOM 3108 O O . VAL B 1 159 ? 5.280 -34.467 40.105 1.00 129.61 ? 159 VAL B O 1 +ATOM 3109 C CB . VAL B 1 159 ? 7.149 -35.324 37.795 1.00 138.38 ? 159 VAL B CB 1 +ATOM 3110 C CG1 . VAL B 1 159 ? 6.939 -33.908 37.292 1.00 148.92 ? 159 VAL B CG1 1 +ATOM 3111 C CG2 . VAL B 1 159 ? 8.332 -35.958 37.076 1.00 146.63 ? 159 VAL B CG2 1 +ATOM 3112 N N . ASN B 1 160 ? 7.124 -33.247 40.482 1.00 79.89 ? 160 ASN B N 1 +ATOM 3113 C CA . ASN B 1 160 ? 6.431 -32.063 40.958 1.00 81.71 ? 160 ASN B CA 1 +ATOM 3114 C C . ASN B 1 160 ? 6.392 -31.031 39.816 1.00 93.38 ? 160 ASN B C 1 +ATOM 3115 O O . ASN B 1 160 ? 7.402 -30.765 39.169 1.00 93.77 ? 160 ASN B O 1 +ATOM 3116 C CB . ASN B 1 160 ? 7.182 -31.500 42.172 1.00 73.35 ? 160 ASN B CB 1 +ATOM 3117 C CG . ASN B 1 160 ? 6.618 -30.181 42.700 1.00 88.16 ? 160 ASN B CG 1 +ATOM 3118 O OD1 . ASN B 1 160 ? 6.275 -29.254 41.939 1.00 79.30 ? 160 ASN B OD1 1 +ATOM 3119 N ND2 . ASN B 1 160 ? 6.527 -30.091 44.023 1.00 79.65 ? 160 ASN B ND2 1 +ATOM 3120 N N . LEU B 1 161 ? 5.206 -30.506 39.541 1.00 99.68 ? 161 LEU B N 1 +ATOM 3121 C CA . LEU B 1 161 ? 5.066 -29.281 38.761 1.00 88.74 ? 161 LEU B CA 1 +ATOM 3122 C C . LEU B 1 161 ? 4.260 -28.275 39.564 1.00 93.20 ? 161 LEU B C 1 +ATOM 3123 O O . LEU B 1 161 ? 3.380 -28.639 40.345 1.00 138.50 ? 161 LEU B O 1 +ATOM 3124 C CB . LEU B 1 161 ? 4.346 -29.553 37.449 1.00 79.15 ? 161 LEU B CB 1 +ATOM 3125 C CG . LEU B 1 161 ? 5.077 -30.455 36.485 1.00 98.77 ? 161 LEU B CG 1 +ATOM 3126 C CD1 . LEU B 1 161 ? 4.169 -30.790 35.310 1.00 97.28 ? 161 LEU B CD1 1 +ATOM 3127 C CD2 . LEU B 1 161 ? 6.363 -29.779 36.023 1.00 119.70 ? 161 LEU B CD2 1 +ATOM 3128 N N . ARG B 1 162 ? 4.550 -27.004 39.394 1.00 79.13 ? 162 ARG B N 1 +ATOM 3129 C CA . ARG B 1 162 ? 3.845 -25.998 40.179 1.00 59.23 ? 162 ARG B CA 1 +ATOM 3130 C C . ARG B 1 162 ? 3.813 -24.642 39.540 1.00 53.22 ? 162 ARG B C 1 +ATOM 3131 O O . ARG B 1 162 ? 4.820 -24.128 39.027 1.00 83.81 ? 162 ARG B O 1 +ATOM 3132 C CB . ARG B 1 162 ? 4.413 -25.902 41.602 1.00 68.78 ? 162 ARG B CB 1 +ATOM 3133 C CG . ARG B 1 162 ? 5.866 -25.450 41.760 1.00 79.90 ? 162 ARG B CG 1 +ATOM 3134 C CD . ARG B 1 162 ? 6.125 -25.003 43.200 1.00 74.85 ? 162 ARG B CD 1 +ATOM 3135 N NE . ARG B 1 162 ? 7.409 -24.360 43.431 1.00 73.05 ? 162 ARG B NE 1 +ATOM 3136 C CZ . ARG B 1 162 ? 8.545 -25.021 43.598 1.00 93.11 ? 162 ARG B CZ 1 +ATOM 3137 N NH1 . ARG B 1 162 ? 8.596 -26.352 43.475 1.00 103.36 ? 162 ARG B NH1 1 +ATOM 3138 N NH2 . ARG B 1 162 ? 9.658 -24.347 43.843 1.00 109.16 ? 162 ARG B NH2 1 +ATOM 3139 N N . VAL B 1 163 ? 2.619 -24.097 39.482 1.00 62.17 ? 163 VAL B N 1 +ATOM 3140 C CA . VAL B 1 163 ? 2.378 -22.778 38.892 1.00 77.59 ? 163 VAL B CA 1 +ATOM 3141 C C . VAL B 1 163 ? 2.673 -21.715 39.928 1.00 53.24 ? 163 VAL B C 1 +ATOM 3142 O O . VAL B 1 163 ? 1.979 -21.667 40.951 1.00 91.99 ? 163 VAL B O 1 +ATOM 3143 C CB . VAL B 1 163 ? 0.891 -22.606 38.445 1.00 92.43 ? 163 VAL B CB 1 +ATOM 3144 C CG1 . VAL B 1 163 ? 0.674 -21.195 37.871 1.00 98.56 ? 163 VAL B CG1 1 +ATOM 3145 C CG2 . VAL B 1 163 ? 0.488 -23.706 37.457 1.00 78.83 ? 163 VAL B CG2 1 +ATOM 3146 N N . VAL B 1 164 ? 3.523 -20.776 39.560 1.00 35.12 ? 164 VAL B N 1 +ATOM 3147 C CA . VAL B 1 164 ? 3.844 -19.644 40.402 1.00 37.86 ? 164 VAL B CA 1 +ATOM 3148 C C . VAL B 1 164 ? 3.375 -18.396 39.747 1.00 38.80 ? 164 VAL B C 1 +ATOM 3149 O O . VAL B 1 164 ? 3.581 -18.198 38.548 1.00 44.33 ? 164 VAL B O 1 +ATOM 3150 C CB . VAL B 1 164 ? 5.356 -19.504 40.594 1.00 50.51 ? 164 VAL B CB 1 +ATOM 3151 C CG1 . VAL B 1 164 ? 5.697 -18.304 41.455 1.00 35.75 ? 164 VAL B CG1 1 +ATOM 3152 C CG2 . VAL B 1 164 ? 5.890 -20.786 41.231 1.00 80.41 ? 164 VAL B CG2 1 +ATOM 3153 N N . ASN B 1 165 ? 2.738 -17.548 40.534 1.00 49.23 ? 165 ASN B N 1 +ATOM 3154 C CA . ASN B 1 165 ? 2.256 -16.280 40.034 1.00 64.08 ? 165 ASN B CA 1 +ATOM 3155 C C . ASN B 1 165 ? 3.393 -15.232 40.073 1.00 90.99 ? 165 ASN B C 1 +ATOM 3156 O O . ASN B 1 165 ? 3.906 -14.882 41.148 1.00 69.47 ? 165 ASN B O 1 +ATOM 3157 C CB . ASN B 1 165 ? 1.080 -15.771 40.845 1.00 62.73 ? 165 ASN B CB 1 +ATOM 3158 C CG . ASN B 1 165 ? 0.403 -14.587 40.188 1.00 83.87 ? 165 ASN B CG 1 +ATOM 3159 O OD1 . ASN B 1 165 ? 0.757 -14.192 39.073 1.00 90.93 ? 165 ASN B OD1 1 +ATOM 3160 N ND2 . ASN B 1 165 ? -0.414 -13.891 40.954 1.00 105.54 ? 165 ASN B ND2 1 +ATOM 3161 N N . VAL B 1 166 ? 3.753 -14.715 38.890 1.00 86.93 ? 166 VAL B N 1 +ATOM 3162 C CA . VAL B 1 166 ? 4.848 -13.752 38.742 1.00 65.72 ? 166 VAL B CA 1 +ATOM 3163 C C . VAL B 1 166 ? 4.580 -12.529 39.574 1.00 62.63 ? 166 VAL B C 1 +ATOM 3164 O O . VAL B 1 166 ? 5.467 -11.980 40.174 1.00 54.30 ? 166 VAL B O 1 +ATOM 3165 C CB . VAL B 1 166 ? 5.047 -13.361 37.251 1.00 62.07 ? 166 VAL B CB 1 +ATOM 3166 C CG1 . VAL B 1 166 ? 5.704 -11.985 37.098 1.00 49.30 ? 166 VAL B CG1 1 +ATOM 3167 C CG2 . VAL B 1 166 ? 5.840 -14.476 36.541 1.00 74.82 ? 166 VAL B CG2 1 +ATOM 3168 N N . SER B 1 167 ? 3.324 -12.111 39.585 1.00 73.17 ? 167 SER B N 1 +ATOM 3169 C CA . SER B 1 167 ? 2.957 -10.837 40.156 1.00 73.17 ? 167 SER B CA 1 +ATOM 3170 C C . SER B 1 167 ? 3.075 -10.843 41.673 1.00 75.85 ? 167 SER B C 1 +ATOM 3171 O O . SER B 1 167 ? 2.970 -9.774 42.288 1.00 70.00 ? 167 SER B O 1 +ATOM 3172 C CB . SER B 1 167 ? 1.543 -10.461 39.685 1.00 80.45 ? 167 SER B CB 1 +ATOM 3173 O OG . SER B 1 167 ? 1.397 -10.666 38.283 1.00 113.27 ? 167 SER B OG 1 +ATOM 3174 N N . THR B 1 168 ? 3.184 -12.033 42.282 1.00 73.94 ? 168 THR B N 1 +ATOM 3175 C CA . THR B 1 168 ? 3.122 -12.131 43.750 1.00 73.71 ? 168 THR B CA 1 +ATOM 3176 C C . THR B 1 168 ? 4.091 -13.103 44.320 1.00 53.09 ? 168 THR B C 1 +ATOM 3177 O O . THR B 1 168 ? 4.653 -12.908 45.427 1.00 67.61 ? 168 THR B O 1 +ATOM 3178 C CB . THR B 1 168 ? 1.731 -12.561 44.273 1.00 84.35 ? 168 THR B CB 1 +ATOM 3179 O OG1 . THR B 1 168 ? 1.298 -13.733 43.584 1.00 71.18 ? 168 THR B OG1 1 +ATOM 3180 C CG2 . THR B 1 168 ? 0.700 -11.441 44.084 1.00 105.64 ? 168 THR B CG2 1 +ATOM 3181 N N . GLY B 1 169 ? 4.304 -14.177 43.598 1.00 45.18 ? 169 GLY B N 1 +ATOM 3182 C CA . GLY B 1 169 ? 5.163 -15.213 44.150 1.00 75.79 ? 169 GLY B CA 1 +ATOM 3183 C C . GLY B 1 169 ? 4.370 -16.281 44.871 1.00 65.21 ? 169 GLY B C 1 +ATOM 3184 O O . GLY B 1 169 ? 4.910 -17.334 45.180 1.00 58.90 ? 169 GLY B O 1 +ATOM 3185 N N . GLU B 1 170 ? 3.098 -16.007 45.124 1.00 65.87 ? 170 GLU B N 1 +ATOM 3186 C CA . GLU B 1 170 ? 2.165 -17.059 45.516 1.00 64.25 ? 170 GLU B CA 1 +ATOM 3187 C C . GLU B 1 170 ? 2.268 -18.203 44.535 1.00 56.25 ? 170 GLU B C 1 +ATOM 3188 O O . GLU B 1 170 ? 2.205 -18.024 43.301 1.00 67.57 ? 170 GLU B O 1 +ATOM 3189 C CB . GLU B 1 170 ? 0.708 -16.553 45.508 1.00 92.95 ? 170 GLU B CB 1 +ATOM 3190 C CG . GLU B 1 170 ? 0.354 -15.673 46.699 1.00 118.31 ? 170 GLU B CG 1 +ATOM 3191 C CD . GLU B 1 170 ? -0.621 -14.541 46.385 1.00 135.11 ? 170 GLU B CD 1 +ATOM 3192 O OE1 . GLU B 1 170 ? -0.863 -14.263 45.191 1.00 142.16 ? 170 GLU B OE1 1 +ATOM 3193 O OE2 . GLU B 1 170 ? -1.061 -13.849 47.331 1.00 136.85 ? 170 GLU B OE2 1 +ATOM 3194 N N . ILE B 1 171 ? 2.452 -19.392 45.055 1.00 46.56 ? 171 ILE B N 1 +ATOM 3195 C CA . ILE B 1 171 ? 2.283 -20.574 44.222 1.00 56.00 ? 171 ILE B CA 1 +ATOM 3196 C C . ILE B 1 171 ? 0.791 -20.797 44.019 1.00 68.06 ? 171 ILE B C 1 +ATOM 3197 O O . ILE B 1 171 ? 0.026 -20.775 44.976 1.00 98.08 ? 171 ILE B O 1 +ATOM 3198 C CB . ILE B 1 171 ? 2.889 -21.808 44.899 1.00 66.28 ? 171 ILE B CB 1 +ATOM 3199 C CG1 . ILE B 1 171 ? 4.423 -21.709 44.870 1.00 93.82 ? 171 ILE B CG1 1 +ATOM 3200 C CG2 . ILE B 1 171 ? 2.395 -23.074 44.212 1.00 59.12 ? 171 ILE B CG2 1 +ATOM 3201 C CD1 . ILE B 1 171 ? 5.114 -22.642 45.835 1.00 84.41 ? 171 ILE B CD1 1 +ATOM 3202 N N . LEU B 1 172 ? 0.360 -20.908 42.771 1.00 77.63 ? 172 LEU B N 1 +ATOM 3203 C CA . LEU B 1 172 ? -1.070 -20.955 42.473 1.00 64.37 ? 172 LEU B CA 1 +ATOM 3204 C C . LEU B 1 172 ? -1.533 -22.388 42.369 1.00 66.62 ? 172 LEU B C 1 +ATOM 3205 O O . LEU B 1 172 ? -2.751 -22.670 42.348 1.00 120.21 ? 172 LEU B O 1 +ATOM 3206 C CB . LEU B 1 172 ? -1.420 -20.181 41.182 1.00 54.39 ? 172 LEU B CB 1 +ATOM 3207 C CG . LEU B 1 172 ? -1.323 -18.635 41.307 1.00 62.14 ? 172 LEU B CG 1 +ATOM 3208 C CD1 . LEU B 1 172 ? -1.780 -17.798 40.111 1.00 61.85 ? 172 LEU B CD1 1 +ATOM 3209 C CD2 . LEU B 1 172 ? -1.927 -18.103 42.608 1.00 70.17 ? 172 LEU B CD2 1 +ATOM 3210 N N . SER B 1 173 ? -0.576 -23.297 42.296 1.00 58.03 ? 173 SER B N 1 +ATOM 3211 C CA . SER B 1 173 ? -0.887 -24.695 42.202 1.00 78.77 ? 173 SER B CA 1 +ATOM 3212 C C . SER B 1 173 ? 0.373 -25.528 42.347 1.00 87.17 ? 173 SER B C 1 +ATOM 3213 O O . SER B 1 173 ? 1.338 -25.335 41.627 1.00 100.21 ? 173 SER B O 1 +ATOM 3214 C CB . SER B 1 173 ? -1.563 -25.007 40.852 1.00 98.72 ? 173 SER B CB 1 +ATOM 3215 O OG . SER B 1 173 ? -1.578 -26.411 40.598 1.00 161.85 ? 173 SER B OG 1 +ATOM 3216 N N . SER B 1 174 ? 0.305 -26.565 43.174 1.00 114.41 ? 174 SER B N 1 +ATOM 3217 C CA . SER B 1 174 ? 1.330 -27.620 43.184 1.00 108.31 ? 174 SER B CA 1 +ATOM 3218 C C . SER B 1 174 ? 0.689 -28.974 42.932 1.00 73.08 ? 174 SER B C 1 +ATOM 3219 O O . SER B 1 174 ? -0.367 -29.276 43.476 1.00 62.04 ? 174 SER B O 1 +ATOM 3220 C CB . SER B 1 174 ? 2.071 -27.646 44.535 1.00 119.97 ? 174 SER B CB 1 +ATOM 3221 O OG . SER B 1 174 ? 3.232 -28.460 44.497 1.00 112.62 ? 174 SER B OG 1 +ATOM 3222 N N . VAL B 1 175 ? 1.341 -29.785 42.113 1.00 68.61 ? 175 VAL B N 1 +ATOM 3223 C CA . VAL B 1 175 ? 0.852 -31.127 41.812 1.00 91.69 ? 175 VAL B CA 1 +ATOM 3224 C C . VAL B 1 175 ? 1.975 -32.141 41.842 1.00 86.21 ? 175 VAL B C 1 +ATOM 3225 O O . VAL B 1 175 ? 3.099 -31.847 41.387 1.00 127.27 ? 175 VAL B O 1 +ATOM 3226 C CB . VAL B 1 175 ? 0.134 -31.185 40.437 1.00 109.82 ? 175 VAL B CB 1 +ATOM 3227 C CG1 . VAL B 1 175 ? -1.097 -30.301 40.446 1.00 132.93 ? 175 VAL B CG1 1 +ATOM 3228 C CG2 . VAL B 1 175 ? 1.042 -30.740 39.303 1.00 124.44 ? 175 VAL B CG2 1 +ATOM 3229 N N . ASN B 1 176 ? 1.639 -33.355 42.251 1.00 78.80 ? 176 ASN B N 1 +ATOM 3230 C CA . ASN B 1 176 ? 2.633 -34.394 42.442 1.00 99.42 ? 176 ASN B CA 1 +ATOM 3231 C C . ASN B 1 176 ? 2.260 -35.678 41.719 1.00 103.20 ? 176 ASN B C 1 +ATOM 3232 O O . ASN B 1 176 ? 1.586 -36.520 42.298 1.00 141.84 ? 176 ASN B O 1 +ATOM 3233 C CB . ASN B 1 176 ? 2.787 -34.643 43.946 1.00 96.69 ? 176 ASN B CB 1 +ATOM 3234 C CG . ASN B 1 176 ? 3.943 -33.852 44.549 1.00 112.92 ? 176 ASN B CG 1 +ATOM 3235 O OD1 . ASN B 1 176 ? 4.477 -32.976 43.883 1.00 109.93 ? 176 ASN B OD1 1 +ATOM 3236 N ND2 . ASN B 1 176 ? 4.391 -34.190 45.785 1.00 148.55 ? 176 ASN B ND2 1 +ATOM 3237 N N . THR B 1 177 ? 2.780 -35.880 40.508 1.00 100.08 ? 177 THR B N 1 +ATOM 3238 C CA . THR B 1 177 ? 2.460 -37.080 39.732 1.00 99.71 ? 177 THR B CA 1 +ATOM 3239 C C . THR B 1 177 ? 3.530 -38.169 39.865 1.00 91.54 ? 177 THR B C 1 +ATOM 3240 O O . THR B 1 177 ? 4.651 -37.907 40.277 1.00 71.48 ? 177 THR B O 1 +ATOM 3241 C CB . THR B 1 177 ? 2.270 -36.767 38.243 1.00 97.26 ? 177 THR B CB 1 +ATOM 3242 O OG1 . THR B 1 177 ? 3.540 -36.441 37.665 1.00 131.68 ? 177 THR B OG1 1 +ATOM 3243 C CG2 . THR B 1 177 ? 1.306 -35.606 38.051 1.00 84.42 ? 177 THR B CG2 1 +ATOM 3244 N N . SER B 1 178 ? 3.139 -39.402 39.559 1.00 91.00 ? 178 SER B N 1 +ATOM 3245 C CA . SER B 1 178 ? 4.006 -40.554 39.741 1.00 96.52 ? 178 SER B CA 1 +ATOM 3246 C C . SER B 1 178 ? 3.754 -41.577 38.648 1.00 92.04 ? 178 SER B C 1 +ATOM 3247 O O . SER B 1 178 ? 2.634 -41.720 38.145 1.00 100.69 ? 178 SER B O 1 +ATOM 3248 C CB . SER B 1 178 ? 3.802 -41.192 41.128 1.00 112.38 ? 178 SER B CB 1 +ATOM 3249 O OG . SER B 1 178 ? 4.400 -42.489 41.210 1.00 167.73 ? 178 SER B OG 1 +ATOM 3250 N N . LYS B 1 179 ? 4.771 -42.380 38.360 1.00 92.93 ? 179 LYS B N 1 +ATOM 3251 C CA . LYS B 1 179 ? 4.652 -43.369 37.306 1.00 101.00 ? 179 LYS B CA 1 +ATOM 3252 C C . LYS B 1 179 ? 5.606 -44.544 37.542 1.00 121.80 ? 179 LYS B C 1 +ATOM 3253 O O . LYS B 1 179 ? 6.704 -44.387 38.086 1.00 141.72 ? 179 LYS B O 1 +ATOM 3254 C CB . LYS B 1 179 ? 4.944 -42.679 35.989 1.00 103.40 ? 179 LYS B CB 1 +ATOM 3255 C CG . LYS B 1 179 ? 4.117 -43.167 34.822 1.00 118.77 ? 179 LYS B CG 1 +ATOM 3256 C CD . LYS B 1 179 ? 4.872 -44.232 34.061 1.00 129.62 ? 179 LYS B CD 1 +ATOM 3257 C CE . LYS B 1 179 ? 3.994 -44.850 32.994 1.00 125.56 ? 179 LYS B CE 1 +ATOM 3258 N NZ . LYS B 1 179 ? 4.596 -46.092 32.447 1.00 112.44 ? 179 LYS B NZ 1 +ATOM 3259 N N . THR B 1 180 ? 5.160 -45.733 37.151 1.00 116.82 ? 180 THR B N 1 +ATOM 3260 C CA . THR B 1 180 ? 5.920 -46.953 37.396 1.00 109.20 ? 180 THR B CA 1 +ATOM 3261 C C . THR B 1 180 ? 6.570 -47.478 36.105 1.00 114.65 ? 180 THR B C 1 +ATOM 3262 O O . THR B 1 180 ? 5.921 -47.544 35.035 1.00 134.53 ? 180 THR B O 1 +ATOM 3263 C CB . THR B 1 180 ? 5.053 -48.044 38.040 1.00 112.39 ? 180 THR B CB 1 +ATOM 3264 O OG1 . THR B 1 180 ? 5.606 -49.333 37.750 1.00 127.34 ? 180 THR B OG1 1 +ATOM 3265 C CG2 . THR B 1 180 ? 3.611 -47.976 37.525 1.00 132.48 ? 180 THR B CG2 1 +ATOM 3266 N N . ILE B 1 181 ? 7.857 -47.813 36.202 1.00 91.94 ? 181 ILE B N 1 +ATOM 3267 C CA . ILE B 1 181 ? 8.603 -48.340 35.060 1.00 93.81 ? 181 ILE B CA 1 +ATOM 3268 C C . ILE B 1 181 ? 8.735 -49.866 35.133 1.00 110.53 ? 181 ILE B C 1 +ATOM 3269 O O . ILE B 1 181 ? 9.294 -50.411 36.087 1.00 89.88 ? 181 ILE B O 1 +ATOM 3270 C CB . ILE B 1 181 ? 10.006 -47.723 34.976 1.00 90.33 ? 181 ILE B CB 1 +ATOM 3271 C CG1 . ILE B 1 181 ? 9.921 -46.196 34.996 1.00 79.25 ? 181 ILE B CG1 1 +ATOM 3272 C CG2 . ILE B 1 181 ? 10.731 -48.159 33.706 1.00 99.60 ? 181 ILE B CG2 1 +ATOM 3273 C CD1 . ILE B 1 181 ? 10.648 -45.573 36.171 1.00 90.36 ? 181 ILE B CD1 1 +ATOM 3274 N N . LEU B 1 182 ? 8.153 -50.550 34.143 1.00 131.35 ? 182 LEU B N 1 +ATOM 3275 C CA . LEU B 1 182 ? 8.089 -52.021 34.125 1.00 141.25 ? 182 LEU B CA 1 +ATOM 3276 C C . LEU B 1 182 ? 9.241 -52.673 33.363 1.00 125.85 ? 182 LEU B C 1 +ATOM 3277 O O . LEU B 1 182 ? 9.618 -52.225 32.280 1.00 106.81 ? 182 LEU B O 1 +ATOM 3278 C CB . LEU B 1 182 ? 6.768 -52.488 33.507 1.00 139.06 ? 182 LEU B CB 1 +ATOM 3279 C CG . LEU B 1 182 ? 6.584 -54.009 33.398 1.00 126.37 ? 182 LEU B CG 1 +ATOM 3280 C CD1 . LEU B 1 182 ? 6.577 -54.710 34.752 1.00 120.82 ? 182 LEU B CD1 1 +ATOM 3281 C CD2 . LEU B 1 182 ? 5.302 -54.276 32.635 1.00 119.31 ? 182 LEU B CD2 1 +ATOM 3282 N N . SER B 1 183 ? 9.738 -53.773 33.919 1.00 129.89 ? 183 SER B N 1 +ATOM 3283 C CA . SER B 1 183 ? 10.761 -54.579 33.275 1.00 117.92 ? 183 SER B CA 1 +ATOM 3284 C C . SER B 1 183 ? 10.456 -56.068 33.494 1.00 85.05 ? 183 SER B C 1 +ATOM 3285 O O . SER B 1 183 ? 10.058 -56.466 34.588 1.00 51.10 ? 183 SER B O 1 +ATOM 3286 C CB . SER B 1 183 ? 12.148 -54.219 33.846 1.00 143.43 ? 183 SER B CB 1 +ATOM 3287 O OG . SER B 1 183 ? 12.254 -52.825 34.103 1.00 113.16 ? 183 SER B OG 1 +ATOM 3288 N N . TYR B 1 184 ? 10.705 -56.880 32.475 1.00 75.21 ? 184 TYR B N 1 +ATOM 3289 C CA . TYR B 1 184 ? 10.527 -58.321 32.602 1.00 76.39 ? 184 TYR B CA 1 +ATOM 3290 C C . TYR B 1 184 ? 11.381 -59.150 31.645 1.00 82.92 ? 184 TYR B C 1 +ATOM 3291 O O . TYR B 1 184 ? 11.841 -58.696 30.583 1.00 65.72 ? 184 TYR B O 1 +ATOM 3292 C CB . TYR B 1 184 ? 9.051 -58.710 32.434 1.00 92.01 ? 184 TYR B CB 1 +ATOM 3293 C CG . TYR B 1 184 ? 8.422 -58.306 31.115 1.00 88.52 ? 184 TYR B CG 1 +ATOM 3294 C CD1 . TYR B 1 184 ? 8.557 -59.098 29.990 1.00 101.32 ? 184 TYR B CD1 1 +ATOM 3295 C CD2 . TYR B 1 184 ? 7.724 -57.123 30.993 1.00 81.85 ? 184 TYR B CD2 1 +ATOM 3296 C CE1 . TYR B 1 184 ? 8.030 -58.708 28.776 1.00 111.55 ? 184 TYR B CE1 1 +ATOM 3297 C CE2 . TYR B 1 184 ? 7.212 -56.712 29.776 1.00 95.34 ? 184 TYR B CE2 1 +ATOM 3298 C CZ . TYR B 1 184 ? 7.358 -57.511 28.672 1.00 102.16 ? 184 TYR B CZ 1 +ATOM 3299 O OH . TYR B 1 184 ? 6.804 -57.120 27.465 1.00 112.97 ? 184 TYR B OH 1 +ATOM 3300 N N . GLU B 1 185 ? 11.564 -60.399 32.045 1.00 94.79 ? 185 GLU B N 1 +ATOM 3301 C CA . GLU B 1 185 ? 12.453 -61.317 31.376 1.00 118.45 ? 185 GLU B CA 1 +ATOM 3302 C C . GLU B 1 185 ? 11.795 -62.687 31.294 1.00 112.98 ? 185 GLU B C 1 +ATOM 3303 O O . GLU B 1 185 ? 11.681 -63.387 32.291 1.00 121.61 ? 185 GLU B O 1 +ATOM 3304 C CB . GLU B 1 185 ? 13.800 -61.338 32.133 1.00 128.77 ? 185 GLU B CB 1 +ATOM 3305 C CG . GLU B 1 185 ? 14.825 -62.388 31.731 1.00 119.04 ? 185 GLU B CG 1 +ATOM 3306 C CD . GLU B 1 185 ? 16.183 -62.128 32.375 1.00 121.19 ? 185 GLU B CD 1 +ATOM 3307 O OE1 . GLU B 1 185 ? 16.327 -61.115 33.093 1.00 116.50 ? 185 GLU B OE1 1 +ATOM 3308 O OE2 . GLU B 1 185 ? 17.100 -62.946 32.177 1.00 120.00 ? 185 GLU B OE2 1 +ATOM 3309 N N . VAL B 1 186 ? 11.436 -63.075 30.078 1.00 109.32 ? 186 VAL B N 1 +ATOM 3310 C CA . VAL B 1 186 ? 10.878 -64.392 29.812 1.00 113.61 ? 186 VAL B CA 1 +ATOM 3311 C C . VAL B 1 186 ? 11.916 -65.324 29.171 1.00 120.69 ? 186 VAL B C 1 +ATOM 3312 O O . VAL B 1 186 ? 12.711 -64.900 28.330 1.00 94.12 ? 186 VAL B O 1 +ATOM 3313 C CB . VAL B 1 186 ? 9.678 -64.274 28.874 1.00 135.68 ? 186 VAL B CB 1 +ATOM 3314 C CG1 . VAL B 1 186 ? 8.948 -65.604 28.765 1.00 134.49 ? 186 VAL B CG1 1 +ATOM 3315 C CG2 . VAL B 1 186 ? 8.734 -63.182 29.362 1.00 148.37 ? 186 VAL B CG2 1 +ATOM 3316 N N . GLN B 1 187 ? 11.933 -66.581 29.608 1.00 135.48 ? 187 GLN B N 1 +ATOM 3317 C CA . GLN B 1 187 ? 12.939 -67.542 29.147 1.00 137.04 ? 187 GLN B CA 1 +ATOM 3318 C C . GLN B 1 187 ? 12.395 -68.962 29.121 1.00 117.57 ? 187 GLN B C 1 +ATOM 3319 O O . GLN B 1 187 ? 11.708 -69.380 30.049 1.00 93.70 ? 187 GLN B O 1 +ATOM 3320 C CB . GLN B 1 187 ? 14.164 -67.521 30.078 1.00 141.40 ? 187 GLN B CB 1 +ATOM 3321 C CG . GLN B 1 187 ? 15.239 -66.488 29.769 1.00 150.27 ? 187 GLN B CG 1 +ATOM 3322 C CD . GLN B 1 187 ? 16.227 -66.319 30.942 1.00 157.42 ? 187 GLN B CD 1 +ATOM 3323 O OE1 . GLN B 1 187 ? 17.029 -65.363 31.009 1.00 210.85 ? 187 GLN B OE1 1 +ATOM 3324 N NE2 . GLN B 1 187 ? 16.185 -67.275 31.871 1.00 139.12 ? 187 GLN B NE2 1 +ATOM 3325 N N . ALA B 1 188 ? 12.717 -69.691 28.059 1.00 122.07 ? 188 ALA B N 1 +ATOM 3326 C CA . ALA B 1 188 ? 12.335 -71.092 27.955 1.00 125.67 ? 188 ALA B CA 1 +ATOM 3327 C C . ALA B 1 188 ? 13.441 -71.884 27.286 1.00 122.25 ? 188 ALA B C 1 +ATOM 3328 O O . ALA B 1 188 ? 14.072 -71.416 26.334 1.00 97.83 ? 188 ALA B O 1 +ATOM 3329 C CB . ALA B 1 188 ? 11.037 -71.237 27.176 1.00 147.91 ? 188 ALA B CB 1 +ATOM 3330 N N . GLY B 1 189 ? 13.688 -73.081 27.794 1.00 124.24 ? 189 GLY B N 1 +ATOM 3331 C CA . GLY B 1 189 ? 14.768 -73.911 27.278 1.00 139.14 ? 189 GLY B CA 1 +ATOM 3332 C C . GLY B 1 189 ? 14.458 -75.391 27.346 1.00 147.08 ? 189 GLY B C 1 +ATOM 3333 O O . GLY B 1 189 ? 13.890 -75.865 28.331 1.00 134.94 ? 189 GLY B O 1 +ATOM 3334 N N . VAL B 1 190 ? 14.836 -76.116 26.297 1.00 159.78 ? 190 VAL B N 1 +ATOM 3335 C CA . VAL B 1 190 ? 14.678 -77.561 26.262 1.00 166.95 ? 190 VAL B CA 1 +ATOM 3336 C C . VAL B 1 190 ? 16.056 -78.232 26.220 1.00 171.78 ? 190 VAL B C 1 +ATOM 3337 O O . VAL B 1 190 ? 16.940 -77.814 25.462 1.00 138.46 ? 190 VAL B O 1 +ATOM 3338 C CB . VAL B 1 190 ? 13.833 -78.001 25.048 1.00 163.97 ? 190 VAL B CB 1 +ATOM 3339 C CG1 . VAL B 1 190 ? 13.464 -79.470 25.167 1.00 147.57 ? 190 VAL B CG1 1 +ATOM 3340 C CG2 . VAL B 1 190 ? 12.580 -77.133 24.909 1.00 153.62 ? 190 VAL B CG2 1 +ATOM 3341 N N . PHE B 1 191 ? 16.232 -79.268 27.038 1.00 188.84 ? 191 PHE B N 1 +ATOM 3342 C CA . PHE B 1 191 ? 17.545 -79.899 27.235 1.00 209.94 ? 191 PHE B CA 1 +ATOM 3343 C C . PHE B 1 191 ? 17.404 -81.436 27.252 1.00 209.73 ? 191 PHE B C 1 +ATOM 3344 O O . PHE B 1 191 ? 16.507 -81.967 27.877 1.00 203.03 ? 191 PHE B O 1 +ATOM 3345 C CB . PHE B 1 191 ? 18.132 -79.431 28.577 1.00 217.22 ? 191 PHE B CB 1 +ATOM 3346 C CG . PHE B 1 191 ? 19.627 -79.592 28.690 1.00 210.81 ? 191 PHE B CG 1 +ATOM 3347 C CD1 . PHE B 1 191 ? 20.192 -80.846 28.849 1.00 183.08 ? 191 PHE B CD1 1 +ATOM 3348 C CD2 . PHE B 1 191 ? 20.460 -78.485 28.679 1.00 221.34 ? 191 PHE B CD2 1 +ATOM 3349 C CE1 . PHE B 1 191 ? 21.563 -80.998 28.954 1.00 175.84 ? 191 PHE B CE1 1 +ATOM 3350 C CE2 . PHE B 1 191 ? 21.830 -78.629 28.812 1.00 203.81 ? 191 PHE B CE2 1 +ATOM 3351 C CZ . PHE B 1 191 ? 22.383 -79.890 28.940 1.00 180.52 ? 191 PHE B CZ 1 +ATOM 3352 N N . ARG B 1 192 ? 18.324 -82.160 26.615 1.00 199.50 ? 192 ARG B N 1 +ATOM 3353 C CA . ARG B 1 192 ? 18.302 -83.638 26.619 1.00 197.98 ? 192 ARG B CA 1 +ATOM 3354 C C . ARG B 1 192 ? 19.669 -84.267 26.400 1.00 178.63 ? 192 ARG B C 1 +ATOM 3355 O O . ARG B 1 192 ? 19.806 -85.485 26.478 1.00 163.68 ? 192 ARG B O 1 +ATOM 3356 C CB . ARG B 1 192 ? 17.330 -84.191 25.571 1.00 184.78 ? 192 ARG B CB 1 +ATOM 3357 C CG . ARG B 1 192 ? 16.079 -84.849 26.133 1.00 172.02 ? 192 ARG B CG 1 +ATOM 3358 C CD . ARG B 1 192 ? 16.255 -85.468 27.526 1.00 158.05 ? 192 ARG B CD 1 +ATOM 3359 N NE . ARG B 1 192 ? 15.004 -85.382 28.296 1.00 160.00 ? 192 ARG B NE 1 +ATOM 3360 C CZ . ARG B 1 192 ? 14.076 -86.333 28.363 1.00 172.81 ? 192 ARG B CZ 1 +ATOM 3361 N NH1 . ARG B 1 192 ? 14.263 -87.492 27.753 1.00 190.35 ? 192 ARG B NH1 1 +ATOM 3362 N NH2 . ARG B 1 192 ? 12.962 -86.131 29.064 1.00 178.15 ? 192 ARG B NH2 1 +ATOM 3363 N N . LEU B 1 200 ? 20.933 -82.563 22.692 1.00 145.21 ? 200 LEU B N 1 +ATOM 3364 C CA . LEU B 1 200 ? 19.966 -81.551 22.273 1.00 165.73 ? 200 LEU B CA 1 +ATOM 3365 C C . LEU B 1 200 ? 19.780 -80.482 23.343 1.00 216.93 ? 200 LEU B C 1 +ATOM 3366 O O . LEU B 1 200 ? 19.255 -80.756 24.431 1.00 240.72 ? 200 LEU B O 1 +ATOM 3367 C CB . LEU B 1 200 ? 18.601 -82.173 21.972 1.00 148.02 ? 200 LEU B CB 1 +ATOM 3368 C CG . LEU B 1 200 ? 17.481 -81.147 21.733 1.00 140.63 ? 200 LEU B CG 1 +ATOM 3369 C CD1 . LEU B 1 200 ? 17.227 -80.996 20.241 1.00 134.49 ? 200 LEU B CD1 1 +ATOM 3370 C CD2 . LEU B 1 200 ? 16.194 -81.477 22.492 1.00 125.14 ? 200 LEU B CD2 1 +ATOM 3371 N N . GLU B 1 201 ? 20.198 -79.261 23.021 1.00 222.58 ? 201 GLU B N 1 +ATOM 3372 C CA . GLU B 1 201 ? 19.761 -78.083 23.761 1.00 185.80 ? 201 GLU B CA 1 +ATOM 3373 C C . GLU B 1 201 ? 19.056 -77.117 22.817 1.00 157.59 ? 201 GLU B C 1 +ATOM 3374 O O . GLU B 1 201 ? 19.406 -77.026 21.648 1.00 135.18 ? 201 GLU B O 1 +ATOM 3375 C CB . GLU B 1 201 ? 20.950 -77.391 24.435 1.00 171.67 ? 201 GLU B CB 1 +ATOM 3376 C CG . GLU B 1 201 ? 20.529 -76.465 25.565 1.00 176.06 ? 201 GLU B CG 1 +ATOM 3377 C CD . GLU B 1 201 ? 21.698 -75.770 26.249 1.00 174.04 ? 201 GLU B CD 1 +ATOM 3378 O OE1 . GLU B 1 201 ? 22.668 -76.458 26.637 1.00 164.53 ? 201 GLU B OE1 1 +ATOM 3379 O OE2 . GLU B 1 201 ? 21.644 -74.533 26.411 1.00 182.50 ? 201 GLU B OE2 1 +ATOM 3380 N N . GLY B 1 202 ? 18.066 -76.400 23.336 1.00 146.49 ? 202 GLY B N 1 +ATOM 3381 C CA . GLY B 1 202 ? 17.418 -75.323 22.599 1.00 164.00 ? 202 GLY B CA 1 +ATOM 3382 C C . GLY B 1 202 ? 16.831 -74.273 23.525 1.00 179.02 ? 202 GLY B C 1 +ATOM 3383 O O . GLY B 1 202 ? 16.077 -74.602 24.442 1.00 206.41 ? 202 GLY B O 1 +ATOM 3384 N N . GLU B 1 203 ? 17.196 -73.008 23.310 1.00 162.85 ? 203 GLU B N 1 +ATOM 3385 C CA . GLU B 1 203 ? 16.774 -71.929 24.198 1.00 142.03 ? 203 GLU B CA 1 +ATOM 3386 C C . GLU B 1 203 ? 16.179 -70.728 23.464 1.00 127.17 ? 203 GLU B C 1 +ATOM 3387 O O . GLU B 1 203 ? 16.728 -70.260 22.468 1.00 103.95 ? 203 GLU B O 1 +ATOM 3388 C CB . GLU B 1 203 ? 17.948 -71.468 25.069 1.00 146.82 ? 203 GLU B CB 1 +ATOM 3389 C CG . GLU B 1 203 ? 18.415 -72.528 26.072 1.00 176.00 ? 203 GLU B CG 1 +ATOM 3390 C CD . GLU B 1 203 ? 19.514 -72.062 27.024 1.00 182.08 ? 203 GLU B CD 1 +ATOM 3391 O OE1 . GLU B 1 203 ? 20.023 -70.935 26.838 1.00 186.35 ? 203 GLU B OE1 1 +ATOM 3392 O OE2 . GLU B 1 203 ? 19.862 -72.829 27.955 1.00 160.10 ? 203 GLU B OE2 1 +ATOM 3393 N N . VAL B 1 204 ? 15.074 -70.221 24.009 1.00 117.28 ? 204 VAL B N 1 +ATOM 3394 C CA . VAL B 1 204 ? 14.527 -68.930 23.625 1.00 104.88 ? 204 VAL B CA 1 +ATOM 3395 C C . VAL B 1 204 ? 14.438 -68.015 24.838 1.00 116.14 ? 204 VAL B C 1 +ATOM 3396 O O . VAL B 1 204 ? 14.075 -68.437 25.949 1.00 108.33 ? 204 VAL B O 1 +ATOM 3397 C CB . VAL B 1 204 ? 13.134 -69.088 23.030 1.00 107.75 ? 204 VAL B CB 1 +ATOM 3398 C CG1 . VAL B 1 204 ? 12.402 -67.753 22.958 1.00 105.15 ? 204 VAL B CG1 1 +ATOM 3399 C CG2 . VAL B 1 204 ? 13.245 -69.716 21.649 1.00 126.86 ? 204 VAL B CG2 1 +ATOM 3400 N N . GLY B 1 205 ? 14.880 -66.778 24.647 1.00 131.69 ? 205 GLY B N 1 +ATOM 3401 C CA . GLY B 1 205 ? 14.856 -65.780 25.711 1.00 128.28 ? 205 GLY B CA 1 +ATOM 3402 C C . GLY B 1 205 ? 14.400 -64.435 25.181 1.00 120.76 ? 205 GLY B C 1 +ATOM 3403 O O . GLY B 1 205 ? 14.660 -64.098 24.015 1.00 101.86 ? 205 GLY B O 1 +ATOM 3404 N N . TYR B 1 206 ? 13.725 -63.669 26.034 1.00 100.97 ? 206 TYR B N 1 +ATOM 3405 C CA . TYR B 1 206 ? 13.297 -62.321 25.686 1.00 112.89 ? 206 TYR B CA 1 +ATOM 3406 C C . TYR B 1 206 ? 13.270 -61.429 26.925 1.00 112.65 ? 206 TYR B C 1 +ATOM 3407 O O . TYR B 1 206 ? 12.884 -61.880 27.995 1.00 115.99 ? 206 TYR B O 1 +ATOM 3408 C CB . TYR B 1 206 ? 11.904 -62.360 25.047 1.00 127.21 ? 206 TYR B CB 1 +ATOM 3409 C CG . TYR B 1 206 ? 11.357 -60.998 24.701 1.00 140.89 ? 206 TYR B CG 1 +ATOM 3410 C CD1 . TYR B 1 206 ? 11.829 -60.293 23.598 1.00 130.72 ? 206 TYR B CD1 1 +ATOM 3411 C CD2 . TYR B 1 206 ? 10.395 -60.396 25.502 1.00 155.57 ? 206 TYR B CD2 1 +ATOM 3412 C CE1 . TYR B 1 206 ? 11.371 -59.022 23.303 1.00 130.23 ? 206 TYR B CE1 1 +ATOM 3413 C CE2 . TYR B 1 206 ? 9.922 -59.131 25.206 1.00 152.01 ? 206 TYR B CE2 1 +ATOM 3414 C CZ . TYR B 1 206 ? 10.420 -58.442 24.115 1.00 126.38 ? 206 TYR B CZ 1 +ATOM 3415 O OH . TYR B 1 206 ? 9.946 -57.180 23.835 1.00 93.64 ? 206 TYR B OH 1 +ATOM 3416 N N . THR B 1 207 ? 13.663 -60.164 26.774 1.00 111.90 ? 207 THR B N 1 +ATOM 3417 C CA . THR B 1 207 ? 13.640 -59.208 27.887 1.00 108.73 ? 207 THR B CA 1 +ATOM 3418 C C . THR B 1 207 ? 13.156 -57.833 27.444 1.00 94.87 ? 207 THR B C 1 +ATOM 3419 O O . THR B 1 207 ? 13.517 -57.349 26.359 1.00 89.04 ? 207 THR B O 1 +ATOM 3420 C CB . THR B 1 207 ? 15.038 -59.029 28.511 1.00 125.79 ? 207 THR B CB 1 +ATOM 3421 O OG1 . THR B 1 207 ? 15.942 -58.503 27.532 1.00 140.75 ? 207 THR B OG1 1 +ATOM 3422 C CG2 . THR B 1 207 ? 15.583 -60.346 29.010 1.00 134.96 ? 207 THR B CG2 1 +ATOM 3423 N N . SER B 1 208 ? 12.336 -57.200 28.278 1.00 84.41 ? 208 SER B N 1 +ATOM 3424 C CA . SER B 1 208 ? 11.788 -55.884 27.940 1.00 89.42 ? 208 SER B CA 1 +ATOM 3425 C C . SER B 1 208 ? 11.813 -54.916 29.112 1.00 67.34 ? 208 SER B C 1 +ATOM 3426 O O . SER B 1 208 ? 11.287 -55.219 30.178 1.00 40.42 ? 208 SER B O 1 +ATOM 3427 C CB . SER B 1 208 ? 10.343 -56.003 27.401 1.00 100.90 ? 208 SER B CB 1 +ATOM 3428 O OG . SER B 1 208 ? 9.757 -54.732 27.193 1.00 98.58 ? 208 SER B OG 1 +ATOM 3429 N N . ASN B 1 209 ? 12.354 -53.730 28.850 1.00 75.73 ? 209 ASN B N 1 +ATOM 3430 C CA . ASN B 1 209 ? 12.342 -52.620 29.798 1.00 90.26 ? 209 ASN B CA 1 +ATOM 3431 C C . ASN B 1 209 ? 11.526 -51.488 29.229 1.00 86.55 ? 209 ASN B C 1 +ATOM 3432 O O . ASN B 1 209 ? 11.653 -51.138 28.041 1.00 99.13 ? 209 ASN B O 1 +ATOM 3433 C CB . ASN B 1 209 ? 13.757 -52.054 30.050 1.00 91.20 ? 209 ASN B CB 1 +ATOM 3434 C CG . ASN B 1 209 ? 14.637 -52.954 30.872 1.00 98.37 ? 209 ASN B CG 1 +ATOM 3435 O OD1 . ASN B 1 209 ? 14.488 -53.056 32.087 1.00 101.27 ? 209 ASN B OD1 1 +ATOM 3436 N ND2 . ASN B 1 209 ? 15.516 -53.679 30.196 1.00 123.05 ? 209 ASN B ND2 1 +ATOM 3437 N N . GLU B 1 210 ? 10.722 -50.873 30.082 1.00 93.32 ? 210 GLU B N 1 +ATOM 3438 C CA . GLU B 1 210 ? 10.076 -49.610 29.714 1.00 108.81 ? 210 GLU B CA 1 +ATOM 3439 C C . GLU B 1 210 ? 11.144 -48.534 29.660 1.00 94.45 ? 210 GLU B C 1 +ATOM 3440 O O . GLU B 1 210 ? 12.077 -48.564 30.436 1.00 95.85 ? 210 GLU B O 1 +ATOM 3441 C CB . GLU B 1 210 ? 9.010 -49.228 30.743 1.00 119.78 ? 210 GLU B CB 1 +ATOM 3442 C CG . GLU B 1 210 ? 7.701 -48.695 30.163 1.00 116.57 ? 210 GLU B CG 1 +ATOM 3443 C CD . GLU B 1 210 ? 6.550 -48.740 31.169 1.00 102.23 ? 210 GLU B CD 1 +ATOM 3444 O OE1 . GLU B 1 210 ? 6.571 -49.566 32.131 1.00 64.58 ? 210 GLU B OE1 1 +ATOM 3445 O OE2 . GLU B 1 210 ? 5.653 -47.891 31.027 1.00 84.39 ? 210 GLU B OE2 1 +ATOM 3446 N N . PRO B 1 211 ? 11.059 -47.626 28.680 1.00 115.62 ? 211 PRO B N 1 +ATOM 3447 C CA . PRO B 1 211 ? 11.981 -46.504 28.681 1.00 112.98 ? 211 PRO B CA 1 +ATOM 3448 C C . PRO B 1 211 ? 11.645 -45.514 29.793 1.00 97.54 ? 211 PRO B C 1 +ATOM 3449 O O . PRO B 1 211 ? 10.505 -45.046 29.905 1.00 63.25 ? 211 PRO B O 1 +ATOM 3450 C CB . PRO B 1 211 ? 11.776 -45.869 27.302 1.00 128.84 ? 211 PRO B CB 1 +ATOM 3451 C CG . PRO B 1 211 ? 11.106 -46.905 26.476 1.00 140.55 ? 211 PRO B CG 1 +ATOM 3452 C CD . PRO B 1 211 ? 10.249 -47.660 27.450 1.00 148.47 ? 211 PRO B CD 1 +ATOM 3453 N N . VAL B 1 212 ? 12.636 -45.244 30.636 1.00 94.23 ? 212 VAL B N 1 +ATOM 3454 C CA . VAL B 1 212 ? 12.479 -44.305 31.736 1.00 91.43 ? 212 VAL B CA 1 +ATOM 3455 C C . VAL B 1 212 ? 12.149 -42.940 31.111 1.00 87.60 ? 212 VAL B C 1 +ATOM 3456 O O . VAL B 1 212 ? 11.356 -42.153 31.657 1.00 58.67 ? 212 VAL B O 1 +ATOM 3457 C CB . VAL B 1 212 ? 13.771 -44.233 32.620 1.00 82.77 ? 212 VAL B CB 1 +ATOM 3458 C CG1 . VAL B 1 212 ? 13.538 -43.324 33.829 1.00 79.39 ? 212 VAL B CG1 1 +ATOM 3459 C CG2 . VAL B 1 212 ? 14.231 -45.625 33.054 1.00 62.95 ? 212 VAL B CG2 1 +ATOM 3460 N N . MET B 1 213 ? 12.851 -42.657 30.011 1.00 89.98 ? 213 MET B N 1 +ATOM 3461 C CA . MET B 1 213 ? 12.652 -41.451 29.212 1.00 94.88 ? 213 MET B CA 1 +ATOM 3462 C C . MET B 1 213 ? 11.240 -41.216 28.747 1.00 86.55 ? 213 MET B C 1 +ATOM 3463 O O . MET B 1 213 ? 10.890 -40.096 28.435 1.00 46.64 ? 213 MET B O 1 +ATOM 3464 C CB . MET B 1 213 ? 13.596 -41.445 28.085 1.00 100.20 ? 213 MET B CB 1 +ATOM 3465 C CG . MET B 1 213 ? 12.910 -41.542 26.793 1.00 83.69 ? 213 MET B CG 1 +ATOM 3466 S SD . MET B 1 213 ? 14.182 -41.653 25.554 1.00 59.62 ? 213 MET B SD 1 +ATOM 3467 C CE . MET B 1 213 ? 12.989 -41.832 24.229 1.00 84.79 ? 213 MET B CE 1 +ATOM 3468 N N . LEU B 1 214 ? 10.486 -42.307 28.594 1.00 102.91 ? 214 LEU B N 1 +ATOM 3469 C CA . LEU B 1 214 ? 9.116 -42.245 28.076 1.00 99.96 ? 214 LEU B CA 1 +ATOM 3470 C C . LEU B 1 214 ? 8.115 -42.168 29.228 1.00 100.65 ? 214 LEU B C 1 +ATOM 3471 O O . LEU B 1 214 ? 7.047 -41.544 29.106 1.00 97.19 ? 214 LEU B O 1 +ATOM 3472 C CB . LEU B 1 214 ? 8.827 -43.474 27.211 1.00 84.97 ? 214 LEU B CB 1 +ATOM 3473 C CG . LEU B 1 214 ? 8.104 -43.286 25.884 1.00 85.06 ? 214 LEU B CG 1 +ATOM 3474 C CD1 . LEU B 1 214 ? 8.851 -42.379 24.924 1.00 71.62 ? 214 LEU B CD1 1 +ATOM 3475 C CD2 . LEU B 1 214 ? 7.864 -44.655 25.240 1.00 95.24 ? 214 LEU B CD2 1 +ATOM 3476 N N . CYS B 1 215 ? 8.488 -42.757 30.363 1.00 86.25 ? 215 CYS B N 1 +ATOM 3477 C CA . CYS B 1 215 ? 7.689 -42.654 31.586 1.00 93.12 ? 215 CYS B CA 1 +ATOM 3478 C C . CYS B 1 215 ? 7.746 -41.248 32.192 1.00 108.09 ? 215 CYS B C 1 +ATOM 3479 O O . CYS B 1 215 ? 6.721 -40.691 32.659 1.00 107.99 ? 215 CYS B O 1 +ATOM 3480 C CB . CYS B 1 215 ? 8.200 -43.631 32.626 1.00 87.01 ? 215 CYS B CB 1 +ATOM 3481 S SG . CYS B 1 215 ? 8.040 -45.344 32.135 1.00 84.18 ? 215 CYS B SG 1 +ATOM 3482 N N . LEU B 1 216 ? 8.952 -40.678 32.191 1.00 98.40 ? 216 LEU B N 1 +ATOM 3483 C CA . LEU B 1 216 ? 9.114 -39.299 32.578 1.00 84.06 ? 216 LEU B CA 1 +ATOM 3484 C C . LEU B 1 216 ? 8.165 -38.412 31.738 1.00 61.55 ? 216 LEU B C 1 +ATOM 3485 O O . LEU B 1 216 ? 7.451 -37.556 32.275 1.00 44.81 ? 216 LEU B O 1 +ATOM 3486 C CB . LEU B 1 216 ? 10.571 -38.868 32.429 1.00 83.46 ? 216 LEU B CB 1 +ATOM 3487 C CG . LEU B 1 216 ? 10.864 -37.401 32.800 1.00 98.15 ? 216 LEU B CG 1 +ATOM 3488 C CD1 . LEU B 1 216 ? 10.454 -37.057 34.220 1.00 95.66 ? 216 LEU B CD1 1 +ATOM 3489 C CD2 . LEU B 1 216 ? 12.343 -37.084 32.606 1.00 96.62 ? 216 LEU B CD2 1 +ATOM 3490 N N . MET B 1 217 ? 8.173 -38.627 30.432 1.00 56.27 ? 217 MET B N 1 +ATOM 3491 C CA . MET B 1 217 ? 7.441 -37.761 29.523 1.00 80.81 ? 217 MET B CA 1 +ATOM 3492 C C . MET B 1 217 ? 5.963 -37.875 29.852 1.00 77.14 ? 217 MET B C 1 +ATOM 3493 O O . MET B 1 217 ? 5.260 -36.864 29.948 1.00 90.32 ? 217 MET B O 1 +ATOM 3494 C CB . MET B 1 217 ? 7.752 -38.106 28.018 1.00 94.99 ? 217 MET B CB 1 +ATOM 3495 C CG . MET B 1 217 ? 7.924 -36.874 27.136 1.00 99.35 ? 217 MET B CG 1 +ATOM 3496 S SD . MET B 1 217 ? 6.379 -35.950 26.907 1.00 71.06 ? 217 MET B SD 1 +ATOM 3497 C CE . MET B 1 217 ? 6.927 -34.448 26.111 1.00 101.73 ? 217 MET B CE 1 +ATOM 3498 N N . SER B 1 218 ? 5.501 -39.113 29.989 1.00 85.73 ? 218 SER B N 1 +ATOM 3499 C CA . SER B 1 218 ? 4.086 -39.405 30.279 1.00 90.68 ? 218 SER B CA 1 +ATOM 3500 C C . SER B 1 218 ? 3.634 -38.690 31.553 1.00 95.86 ? 218 SER B C 1 +ATOM 3501 O O . SER B 1 218 ? 2.616 -37.997 31.566 1.00 89.33 ? 218 SER B O 1 +ATOM 3502 C CB . SER B 1 218 ? 3.891 -40.919 30.441 1.00 77.47 ? 218 SER B CB 1 +ATOM 3503 O OG . SER B 1 218 ? 2.524 -41.230 30.532 1.00 66.75 ? 218 SER B OG 1 +ATOM 3504 N N . ALA B 1 219 ? 4.443 -38.806 32.599 1.00 92.31 ? 219 ALA B N 1 +ATOM 3505 C CA . ALA B 1 219 ? 4.084 -38.252 33.893 1.00 97.67 ? 219 ALA B CA 1 +ATOM 3506 C C . ALA B 1 219 ? 4.034 -36.717 33.875 1.00 88.07 ? 219 ALA B C 1 +ATOM 3507 O O . ALA B 1 219 ? 3.190 -36.093 34.533 1.00 95.11 ? 219 ALA B O 1 +ATOM 3508 C CB . ALA B 1 219 ? 5.063 -38.746 34.943 1.00 116.24 ? 219 ALA B CB 1 +ATOM 3509 N N . ILE B 1 220 ? 4.908 -36.112 33.086 1.00 78.29 ? 220 ILE B N 1 +ATOM 3510 C CA . ILE B 1 220 ? 4.909 -34.654 32.950 1.00 80.10 ? 220 ILE B CA 1 +ATOM 3511 C C . ILE B 1 220 ? 3.640 -34.163 32.249 1.00 85.90 ? 220 ILE B C 1 +ATOM 3512 O O . ILE B 1 220 ? 3.045 -33.167 32.648 1.00 78.51 ? 220 ILE B O 1 +ATOM 3513 C CB . ILE B 1 220 ? 6.173 -34.150 32.194 1.00 74.06 ? 220 ILE B CB 1 +ATOM 3514 C CG1 . ILE B 1 220 ? 7.420 -34.380 33.085 1.00 82.64 ? 220 ILE B CG1 1 +ATOM 3515 C CG2 . ILE B 1 220 ? 6.043 -32.674 31.815 1.00 46.93 ? 220 ILE B CG2 1 +ATOM 3516 C CD1 . ILE B 1 220 ? 8.736 -34.311 32.354 1.00 75.37 ? 220 ILE B CD1 1 +ATOM 3517 N N . GLU B 1 221 ? 3.233 -34.864 31.199 1.00 90.80 ? 221 GLU B N 1 +ATOM 3518 C CA . GLU B 1 221 ? 1.984 -34.542 30.511 1.00 84.19 ? 221 GLU B CA 1 +ATOM 3519 C C . GLU B 1 221 ? 0.825 -34.560 31.504 1.00 81.30 ? 221 GLU B C 1 +ATOM 3520 O O . GLU B 1 221 ? 0.020 -33.629 31.565 1.00 75.18 ? 221 GLU B O 1 +ATOM 3521 C CB . GLU B 1 221 ? 1.747 -35.547 29.367 1.00 107.10 ? 221 GLU B CB 1 +ATOM 3522 C CG . GLU B 1 221 ? 2.661 -35.327 28.168 1.00 137.48 ? 221 GLU B CG 1 +ATOM 3523 C CD . GLU B 1 221 ? 2.745 -36.524 27.222 1.00 163.64 ? 221 GLU B CD 1 +ATOM 3524 O OE1 . GLU B 1 221 ? 2.706 -37.702 27.686 1.00 91.53 ? 221 GLU B OE1 1 +ATOM 3525 O OE2 . GLU B 1 221 ? 2.848 -36.261 25.995 1.00 194.32 ? 221 GLU B OE2 1 +ATOM 3526 N N . THR B 1 222 ? 0.717 -35.675 32.229 1.00 93.28 ? 222 THR B N 1 +ATOM 3527 C CA . THR B 1 222 ? -0.328 -35.893 33.228 1.00 81.83 ? 222 THR B CA 1 +ATOM 3528 C C . THR B 1 222 ? -0.369 -34.727 34.190 1.00 74.88 ? 222 THR B C 1 +ATOM 3529 O O . THR B 1 222 ? -1.440 -34.187 34.499 1.00 88.60 ? 222 THR B O 1 +ATOM 3530 C CB . THR B 1 222 ? -0.043 -37.192 34.027 1.00 77.42 ? 222 THR B CB 1 +ATOM 3531 O OG1 . THR B 1 222 ? -0.302 -38.348 33.208 1.00 54.67 ? 222 THR B OG1 1 +ATOM 3532 C CG2 . THR B 1 222 ? -0.881 -37.242 35.316 1.00 89.81 ? 222 THR B CG2 1 +ATOM 3533 N N . GLY B 1 223 ? 0.801 -34.361 34.685 1.00 70.92 ? 223 GLY B N 1 +ATOM 3534 C CA . GLY B 1 223 ? 0.925 -33.199 35.554 1.00 98.50 ? 223 GLY B CA 1 +ATOM 3535 C C . GLY B 1 223 ? 0.352 -31.929 34.926 1.00 84.38 ? 223 GLY B C 1 +ATOM 3536 O O . GLY B 1 223 ? -0.255 -31.101 35.635 1.00 73.03 ? 223 GLY B O 1 +ATOM 3537 N N . VAL B 1 224 ? 0.605 -31.733 33.627 1.00 62.55 ? 224 VAL B N 1 +ATOM 3538 C CA . VAL B 1 224 ? 0.178 -30.516 32.971 1.00 68.02 ? 224 VAL B CA 1 +ATOM 3539 C C . VAL B 1 224 ? -1.335 -30.486 32.958 1.00 81.06 ? 224 VAL B C 1 +ATOM 3540 O O . VAL B 1 224 ? -1.949 -29.446 33.201 1.00 88.36 ? 224 VAL B O 1 +ATOM 3541 C CB . VAL B 1 224 ? 0.711 -30.431 31.545 1.00 78.85 ? 224 VAL B CB 1 +ATOM 3542 C CG1 . VAL B 1 224 ? 0.061 -29.269 30.811 1.00 83.40 ? 224 VAL B CG1 1 +ATOM 3543 C CG2 . VAL B 1 224 ? 2.230 -30.270 31.547 1.00 91.98 ? 224 VAL B CG2 1 +ATOM 3544 N N . ILE B 1 225 ? -1.944 -31.641 32.709 1.00 108.91 ? 225 ILE B N 1 +ATOM 3545 C CA . ILE B 1 225 ? -3.407 -31.738 32.712 1.00 99.32 ? 225 ILE B CA 1 +ATOM 3546 C C . ILE B 1 225 ? -3.976 -31.374 34.079 1.00 94.98 ? 225 ILE B C 1 +ATOM 3547 O O . ILE B 1 225 ? -4.833 -30.494 34.169 1.00 80.05 ? 225 ILE B O 1 +ATOM 3548 C CB . ILE B 1 225 ? -3.896 -33.137 32.311 1.00 83.51 ? 225 ILE B CB 1 +ATOM 3549 C CG1 . ILE B 1 225 ? -3.581 -33.394 30.840 1.00 87.56 ? 225 ILE B CG1 1 +ATOM 3550 C CG2 . ILE B 1 225 ? -5.398 -33.241 32.519 1.00 95.37 ? 225 ILE B CG2 1 +ATOM 3551 C CD1 . ILE B 1 225 ? -3.635 -34.855 30.456 1.00 96.98 ? 225 ILE B CD1 1 +ATOM 3552 N N . PHE B 1 226 ? -3.473 -32.021 35.132 1.00 95.96 ? 226 PHE B N 1 +ATOM 3553 C CA . PHE B 1 226 ? -3.898 -31.713 36.502 1.00 101.65 ? 226 PHE B CA 1 +ATOM 3554 C C . PHE B 1 226 ? -3.733 -30.216 36.830 1.00 92.97 ? 226 PHE B C 1 +ATOM 3555 O O . PHE B 1 226 ? -4.528 -29.658 37.597 1.00 121.85 ? 226 PHE B O 1 +ATOM 3556 C CB . PHE B 1 226 ? -3.135 -32.557 37.542 1.00 99.09 ? 226 PHE B CB 1 +ATOM 3557 C CG . PHE B 1 226 ? -3.646 -33.968 37.689 1.00 91.84 ? 226 PHE B CG 1 +ATOM 3558 C CD1 . PHE B 1 226 ? -4.947 -34.217 38.069 1.00 96.20 ? 226 PHE B CD1 1 +ATOM 3559 C CD2 . PHE B 1 226 ? -2.791 -35.052 37.500 1.00 97.26 ? 226 PHE B CD2 1 +ATOM 3560 C CE1 . PHE B 1 226 ? -5.404 -35.520 38.203 1.00 98.44 ? 226 PHE B CE1 1 +ATOM 3561 C CE2 . PHE B 1 226 ? -3.234 -36.356 37.665 1.00 76.11 ? 226 PHE B CE2 1 +ATOM 3562 C CZ . PHE B 1 226 ? -4.543 -36.588 37.995 1.00 83.49 ? 226 PHE B CZ 1 +ATOM 3563 N N . LEU B 1 227 ? -2.709 -29.581 36.270 1.00 60.03 ? 227 LEU B N 1 +ATOM 3564 C CA . LEU B 1 227 ? -2.488 -28.171 36.496 1.00 62.42 ? 227 LEU B CA 1 +ATOM 3565 C C . LEU B 1 227 ? -3.572 -27.350 35.841 1.00 62.02 ? 227 LEU B C 1 +ATOM 3566 O O . LEU B 1 227 ? -4.076 -26.394 36.427 1.00 54.61 ? 227 LEU B O 1 +ATOM 3567 C CB . LEU B 1 227 ? -1.110 -27.779 35.962 1.00 84.35 ? 227 LEU B CB 1 +ATOM 3568 C CG . LEU B 1 227 ? 0.099 -28.142 36.850 1.00 101.25 ? 227 LEU B CG 1 +ATOM 3569 C CD1 . LEU B 1 227 ? 1.453 -28.024 36.187 1.00 122.66 ? 227 LEU B CD1 1 +ATOM 3570 C CD2 . LEU B 1 227 ? 0.110 -27.336 38.126 1.00 96.35 ? 227 LEU B CD2 1 +ATOM 3571 N N . ILE B 1 228 ? -3.923 -27.708 34.614 1.00 76.00 ? 228 ILE B N 1 +ATOM 3572 C CA . ILE B 1 228 ? -4.930 -26.954 33.858 1.00 93.89 ? 228 ILE B CA 1 +ATOM 3573 C C . ILE B 1 228 ? -6.283 -27.095 34.533 1.00 92.27 ? 228 ILE B C 1 +ATOM 3574 O O . ILE B 1 228 ? -6.982 -26.116 34.764 1.00 65.43 ? 228 ILE B O 1 +ATOM 3575 C CB . ILE B 1 228 ? -5.062 -27.436 32.389 1.00 98.35 ? 228 ILE B CB 1 +ATOM 3576 C CG1 . ILE B 1 228 ? -3.773 -27.168 31.605 1.00 103.03 ? 228 ILE B CG1 1 +ATOM 3577 C CG2 . ILE B 1 228 ? -6.190 -26.699 31.701 1.00 102.18 ? 228 ILE B CG2 1 +ATOM 3578 C CD1 . ILE B 1 228 ? -3.665 -27.915 30.294 1.00 85.68 ? 228 ILE B CD1 1 +ATOM 3579 N N . ASN B 1 229 ? -6.634 -28.333 34.857 1.00 100.93 ? 229 ASN B N 1 +ATOM 3580 C CA . ASN B 1 229 ? -7.894 -28.613 35.529 1.00 108.14 ? 229 ASN B CA 1 +ATOM 3581 C C . ASN B 1 229 ? -7.982 -27.849 36.851 1.00 113.30 ? 229 ASN B C 1 +ATOM 3582 O O . ASN B 1 229 ? -9.016 -27.267 37.178 1.00 117.23 ? 229 ASN B O 1 +ATOM 3583 C CB . ASN B 1 229 ? -8.041 -30.121 35.765 1.00 112.29 ? 229 ASN B CB 1 +ATOM 3584 C CG . ASN B 1 229 ? -9.450 -30.519 36.119 1.00 109.70 ? 229 ASN B CG 1 +ATOM 3585 O OD1 . ASN B 1 229 ? -10.418 -29.856 35.717 1.00 137.91 ? 229 ASN B OD1 1 +ATOM 3586 N ND2 . ASN B 1 229 ? -9.588 -31.671 36.771 1.00 93.31 ? 229 ASN B ND2 1 +ATOM 3587 N N . ASP B 1 230 ? -6.882 -27.857 37.605 1.00 126.38 ? 230 ASP B N 1 +ATOM 3588 C CA . ASP B 1 230 ? -6.810 -27.178 38.900 1.00 117.15 ? 230 ASP B CA 1 +ATOM 3589 C C . ASP B 1 230 ? -6.973 -25.677 38.727 1.00 90.33 ? 230 ASP B C 1 +ATOM 3590 O O . ASP B 1 230 ? -7.728 -25.039 39.478 1.00 98.78 ? 230 ASP B O 1 +ATOM 3591 C CB . ASP B 1 230 ? -5.474 -27.461 39.586 1.00 120.52 ? 230 ASP B CB 1 +ATOM 3592 C CG . ASP B 1 230 ? -5.402 -26.871 40.981 1.00 145.04 ? 230 ASP B CG 1 +ATOM 3593 O OD1 . ASP B 1 230 ? -6.063 -27.423 41.882 1.00 213.27 ? 230 ASP B OD1 1 +ATOM 3594 O OD2 . ASP B 1 230 ? -4.719 -25.859 41.184 1.00 147.68 ? 230 ASP B OD2 1 +ATOM 3595 N N . GLY B 1 231 ? -6.357 -25.150 37.683 1.00 71.45 ? 231 GLY B N 1 +ATOM 3596 C CA . GLY B 1 231 ? -6.508 -23.752 37.371 1.00 98.69 ? 231 GLY B CA 1 +ATOM 3597 C C . GLY B 1 231 ? -7.917 -23.356 36.926 1.00 114.90 ? 231 GLY B C 1 +ATOM 3598 O O . GLY B 1 231 ? -8.408 -22.251 37.249 1.00 96.95 ? 231 GLY B O 1 +ATOM 3599 N N . ILE B 1 232 ? -8.588 -24.264 36.218 1.00 123.91 ? 232 ILE B N 1 +ATOM 3600 C CA . ILE B 1 232 ? -10.000 -24.064 35.837 1.00 118.92 ? 232 ILE B CA 1 +ATOM 3601 C C . ILE B 1 232 ? -10.913 -23.954 37.062 1.00 90.77 ? 232 ILE B C 1 +ATOM 3602 O O . ILE B 1 232 ? -11.648 -22.986 37.196 1.00 64.52 ? 232 ILE B O 1 +ATOM 3603 C CB . ILE B 1 232 ? -10.512 -25.216 34.940 1.00 131.20 ? 232 ILE B CB 1 +ATOM 3604 C CG1 . ILE B 1 232 ? -9.885 -25.099 33.546 1.00 135.02 ? 232 ILE B CG1 1 +ATOM 3605 C CG2 . ILE B 1 232 ? -12.041 -25.212 34.859 1.00 132.10 ? 232 ILE B CG2 1 +ATOM 3606 C CD1 . ILE B 1 232 ? -9.974 -26.366 32.728 1.00 132.45 ? 232 ILE B CD1 1 +ATOM 3607 N N . ASP B 1 233 ? -10.809 -24.928 37.967 1.00 86.02 ? 233 ASP B N 1 +ATOM 3608 C CA . ASP B 1 233 ? -11.510 -24.891 39.257 1.00 84.92 ? 233 ASP B CA 1 +ATOM 3609 C C . ASP B 1 233 ? -11.258 -23.578 40.013 1.00 100.06 ? 233 ASP B C 1 +ATOM 3610 O O . ASP B 1 233 ? -12.188 -22.947 40.488 1.00 84.13 ? 233 ASP B O 1 +ATOM 3611 C CB . ASP B 1 233 ? -11.088 -26.082 40.147 1.00 101.08 ? 233 ASP B CB 1 +ATOM 3612 C CG . ASP B 1 233 ? -11.480 -27.434 39.557 1.00 107.96 ? 233 ASP B CG 1 +ATOM 3613 O OD1 . ASP B 1 233 ? -11.876 -27.467 38.365 1.00 122.37 ? 233 ASP B OD1 1 +ATOM 3614 O OD2 . ASP B 1 233 ? -11.314 -28.460 40.257 1.00 70.42 ? 233 ASP B OD2 1 +ATOM 3615 N N . ARG B 1 234 ? -9.988 -23.178 40.143 1.00 112.96 ? 234 ARG B N 1 +ATOM 3616 C CA . ARG B 1 234 ? -9.614 -22.048 41.004 1.00 95.90 ? 234 ARG B CA 1 +ATOM 3617 C C . ARG B 1 234 ? -9.805 -20.686 40.341 1.00 90.80 ? 234 ARG B C 1 +ATOM 3618 O O . ARG B 1 234 ? -9.522 -19.654 40.949 1.00 105.47 ? 234 ARG B O 1 +ATOM 3619 C CB . ARG B 1 234 ? -8.167 -22.221 41.501 1.00 98.04 ? 234 ARG B CB 1 +ATOM 3620 C CG . ARG B 1 234 ? -8.042 -23.289 42.571 1.00 79.23 ? 234 ARG B CG 1 +ATOM 3621 C CD . ARG B 1 234 ? -6.644 -23.817 42.690 1.00 75.74 ? 234 ARG B CD 1 +ATOM 3622 N NE . ARG B 1 234 ? -6.653 -24.886 43.669 1.00 96.76 ? 234 ARG B NE 1 +ATOM 3623 C CZ . ARG B 1 234 ? -5.898 -24.917 44.762 1.00 124.85 ? 234 ARG B CZ 1 +ATOM 3624 N NH1 . ARG B 1 234 ? -5.047 -23.932 45.006 1.00 159.94 ? 234 ARG B NH1 1 +ATOM 3625 N NH2 . ARG B 1 234 ? -5.970 -25.951 45.603 1.00 113.96 ? 234 ARG B NH2 1 +ATOM 3626 N N . GLY B 1 235 ? -10.227 -20.682 39.083 1.00 92.00 ? 235 GLY B N 1 +ATOM 3627 C CA . GLY B 1 235 ? -10.481 -19.434 38.373 1.00 96.13 ? 235 GLY B CA 1 +ATOM 3628 C C . GLY B 1 235 ? -9.218 -18.714 37.926 1.00 112.84 ? 235 GLY B C 1 +ATOM 3629 O O . GLY B 1 235 ? -9.196 -17.486 37.864 1.00 108.47 ? 235 GLY B O 1 +ATOM 3630 N N . LEU B 1 236 ? -8.166 -19.467 37.582 1.00 136.07 ? 236 LEU B N 1 +ATOM 3631 C CA . LEU B 1 236 ? -6.988 -18.870 36.900 1.00 114.38 ? 236 LEU B CA 1 +ATOM 3632 C C . LEU B 1 236 ? -7.342 -18.584 35.452 1.00 112.53 ? 236 LEU B C 1 +ATOM 3633 O O . LEU B 1 236 ? -7.122 -17.481 34.951 1.00 128.20 ? 236 LEU B O 1 +ATOM 3634 C CB . LEU B 1 236 ? -5.762 -19.787 36.936 1.00 110.73 ? 236 LEU B CB 1 +ATOM 3635 C CG . LEU B 1 236 ? -4.883 -19.756 38.195 1.00 120.79 ? 236 LEU B CG 1 +ATOM 3636 C CD1 . LEU B 1 236 ? -5.526 -20.568 39.313 1.00 143.17 ? 236 LEU B CD1 1 +ATOM 3637 C CD2 . LEU B 1 236 ? -3.504 -20.316 37.880 1.00 135.15 ? 236 LEU B CD2 1 +ATOM 3638 N N . TRP B 1 237 ? -7.949 -19.568 34.797 1.00 124.41 ? 237 TRP B N 1 +ATOM 3639 C CA . TRP B 1 237 ? -8.338 -19.441 33.392 1.00 135.23 ? 237 TRP B CA 1 +ATOM 3640 C C . TRP B 1 237 ? -9.719 -20.081 33.152 1.00 127.43 ? 237 TRP B C 1 +ATOM 3641 O O . TRP B 1 237 ? -10.212 -20.839 33.986 1.00 99.55 ? 237 TRP B O 1 +ATOM 3642 C CB . TRP B 1 237 ? -7.262 -20.066 32.494 1.00 124.27 ? 237 TRP B CB 1 +ATOM 3643 C CG . TRP B 1 237 ? -6.600 -21.255 33.114 1.00 109.25 ? 237 TRP B CG 1 +ATOM 3644 C CD1 . TRP B 1 237 ? -7.176 -22.461 33.386 1.00 106.23 ? 237 TRP B CD1 1 +ATOM 3645 C CD2 . TRP B 1 237 ? -5.254 -21.338 33.582 1.00 86.89 ? 237 TRP B CD2 1 +ATOM 3646 N NE1 . TRP B 1 237 ? -6.270 -23.292 33.984 1.00 109.26 ? 237 TRP B NE1 1 +ATOM 3647 C CE2 . TRP B 1 237 ? -5.072 -22.637 34.095 1.00 104.54 ? 237 TRP B CE2 1 +ATOM 3648 C CE3 . TRP B 1 237 ? -4.181 -20.451 33.606 1.00 79.73 ? 237 TRP B CE3 1 +ATOM 3649 C CZ2 . TRP B 1 237 ? -3.854 -23.068 34.633 1.00 100.22 ? 237 TRP B CZ2 1 +ATOM 3650 C CZ3 . TRP B 1 237 ? -2.969 -20.886 34.140 1.00 91.75 ? 237 TRP B CZ3 1 +ATOM 3651 C CH2 . TRP B 1 237 ? -2.824 -22.175 34.659 1.00 89.19 ? 237 TRP B CH2 1 +ATOM 3652 N N . ASP B 1 238 ? -10.324 -19.767 32.010 1.00 120.70 ? 238 ASP B N 1 +ATOM 3653 C CA . ASP B 1 238 ? -11.695 -20.181 31.719 1.00 112.03 ? 238 ASP B CA 1 +ATOM 3654 C C . ASP B 1 238 ? -11.855 -20.854 30.359 1.00 102.09 ? 238 ASP B C 1 +ATOM 3655 O O . ASP B 1 238 ? -11.136 -20.543 29.401 1.00 104.91 ? 238 ASP B O 1 +ATOM 3656 C CB . ASP B 1 238 ? -12.630 -18.987 31.789 1.00 123.84 ? 238 ASP B CB 1 +ATOM 3657 C CG . ASP B 1 238 ? -12.573 -18.286 33.133 1.00 131.93 ? 238 ASP B CG 1 +ATOM 3658 O OD1 . ASP B 1 238 ? -11.638 -17.478 33.323 1.00 121.36 ? 238 ASP B OD1 1 +ATOM 3659 O OD2 . ASP B 1 238 ? -13.482 -18.498 33.972 1.00 132.76 ? 238 ASP B OD2 1 +ATOM 3660 N N . LEU B 1 239 ? -12.794 -21.793 30.294 1.00 88.70 ? 239 LEU B N 1 +ATOM 3661 C CA . LEU B 1 239 ? -13.051 -22.549 29.080 1.00 93.90 ? 239 LEU B CA 1 +ATOM 3662 C C . LEU B 1 239 ? -13.810 -21.693 28.076 1.00 100.33 ? 239 LEU B C 1 +ATOM 3663 O O . LEU B 1 239 ? -14.656 -20.881 28.449 1.00 98.94 ? 239 LEU B O 1 +ATOM 3664 C CB . LEU B 1 239 ? -13.859 -23.817 29.393 1.00 101.91 ? 239 LEU B CB 1 +ATOM 3665 C CG . LEU B 1 239 ? -13.163 -25.030 30.019 1.00 109.74 ? 239 LEU B CG 1 +ATOM 3666 C CD1 . LEU B 1 239 ? -14.124 -26.205 30.142 1.00 104.61 ? 239 LEU B CD1 1 +ATOM 3667 C CD2 . LEU B 1 239 ? -11.958 -25.433 29.200 1.00 122.27 ? 239 LEU B CD2 1 +ATOM 3668 N N . GLN B 1 240 ? -13.515 -21.907 26.799 1.00 108.59 ? 240 GLN B N 1 +ATOM 3669 C CA . GLN B 1 240 ? -14.300 -21.326 25.723 1.00 115.55 ? 240 GLN B CA 1 +ATOM 3670 C C . GLN B 1 240 ? -15.774 -21.694 25.894 1.00 133.39 ? 240 GLN B C 1 +ATOM 3671 O O . GLN B 1 240 ? -16.643 -20.826 25.963 1.00 125.36 ? 240 GLN B O 1 +ATOM 3672 C CB . GLN B 1 240 ? -13.779 -21.822 24.362 1.00 115.61 ? 240 GLN B CB 1 +ATOM 3673 C CG . GLN B 1 240 ? -14.406 -21.114 23.172 1.00 129.67 ? 240 GLN B CG 1 +ATOM 3674 C CD . GLN B 1 240 ? -14.045 -19.635 23.139 1.00 145.15 ? 240 GLN B CD 1 +ATOM 3675 O OE1 . GLN B 1 240 ? -12.964 -19.259 22.683 1.00 147.56 ? 240 GLN B OE1 1 +ATOM 3676 N NE2 . GLN B 1 240 ? -14.948 -18.788 23.632 1.00 151.32 ? 240 GLN B NE2 1 +ATOM 3677 N N . ASN B 1 241 ? -16.034 -22.995 25.952 1.00 163.52 ? 241 ASN B N 1 +ATOM 3678 C CA . ASN B 1 241 ? -17.383 -23.526 26.126 1.00 156.13 ? 241 ASN B CA 1 +ATOM 3679 C C . ASN B 1 241 ? -17.586 -24.022 27.542 1.00 155.39 ? 241 ASN B C 1 +ATOM 3680 O O . ASN B 1 241 ? -17.021 -25.061 27.933 1.00 161.49 ? 241 ASN B O 1 +ATOM 3681 C CB . ASN B 1 241 ? -17.616 -24.685 25.161 1.00 163.37 ? 241 ASN B CB 1 +ATOM 3682 C CG . ASN B 1 241 ? -18.414 -24.272 23.956 1.00 161.48 ? 241 ASN B CG 1 +ATOM 3683 O OD1 . ASN B 1 241 ? -19.604 -24.557 23.871 1.00 134.76 ? 241 ASN B OD1 1 +ATOM 3684 N ND2 . ASN B 1 241 ? -17.763 -23.594 23.007 1.00 192.98 ? 241 ASN B ND2 1 +ATOM 3685 N N . LYS B 1 242 ? -18.411 -23.303 28.295 1.00 119.23 ? 242 LYS B N 1 +ATOM 3686 C CA . LYS B 1 242 ? -18.691 -23.682 29.669 1.00 116.45 ? 242 LYS B CA 1 +ATOM 3687 C C . LYS B 1 242 ? -19.411 -25.029 29.696 1.00 126.95 ? 242 LYS B C 1 +ATOM 3688 O O . LYS B 1 242 ? -19.322 -25.786 30.677 1.00 105.42 ? 242 LYS B O 1 +ATOM 3689 C CB . LYS B 1 242 ? -19.513 -22.596 30.357 1.00 110.16 ? 242 LYS B CB 1 +ATOM 3690 C CG . LYS B 1 242 ? -18.947 -21.196 30.173 1.00 99.18 ? 242 LYS B CG 1 +ATOM 3691 C CD . LYS B 1 242 ? -18.731 -20.492 31.503 1.00 114.14 ? 242 LYS B CD 1 +ATOM 3692 C CE . LYS B 1 242 ? -17.361 -19.837 31.560 1.00 122.93 ? 242 LYS B CE 1 +ATOM 3693 N NZ . LYS B 1 242 ? -17.172 -19.005 32.779 1.00 137.29 ? 242 LYS B NZ 1 +ATOM 3694 N N . ALA B 1 243 ? -20.100 -25.321 28.589 1.00 158.27 ? 243 ALA B N 1 +ATOM 3695 C CA . ALA B 1 243 ? -20.767 -26.604 28.363 1.00 165.16 ? 243 ALA B CA 1 +ATOM 3696 C C . ALA B 1 243 ? -19.770 -27.754 28.330 1.00 160.44 ? 243 ALA B C 1 +ATOM 3697 O O . ALA B 1 243 ? -20.163 -28.919 28.495 1.00 184.16 ? 243 ALA B O 1 +ATOM 3698 C CB . ALA B 1 243 ? -21.559 -26.568 27.057 1.00 150.00 ? 243 ALA B CB 1 +ATOM 3699 N N . GLU B 1 244 ? -18.492 -27.439 28.110 1.00 132.58 ? 244 GLU B N 1 +ATOM 3700 C CA . GLU B 1 244 ? -17.477 -28.478 28.004 1.00 136.40 ? 244 GLU B CA 1 +ATOM 3701 C C . GLU B 1 244 ? -16.791 -28.744 29.331 1.00 110.32 ? 244 GLU B C 1 +ATOM 3702 O O . GLU B 1 244 ? -15.804 -29.471 29.362 1.00 138.93 ? 244 GLU B O 1 +ATOM 3703 C CB . GLU B 1 244 ? -16.435 -28.125 26.943 1.00 144.35 ? 244 GLU B CB 1 +ATOM 3704 C CG . GLU B 1 244 ? -16.935 -28.248 25.512 1.00 148.42 ? 244 GLU B CG 1 +ATOM 3705 C CD . GLU B 1 244 ? -15.821 -28.144 24.490 1.00 155.19 ? 244 GLU B CD 1 +ATOM 3706 O OE1 . GLU B 1 244 ? -15.341 -27.012 24.236 1.00 192.61 ? 244 GLU B OE1 1 +ATOM 3707 O OE2 . GLU B 1 244 ? -15.416 -29.194 23.945 1.00 140.05 ? 244 GLU B OE2 1 +ATOM 3708 N N . ARG B 1 245 ? -17.328 -28.205 30.422 1.00 98.87 ? 245 ARG B N 1 +ATOM 3709 C CA . ARG B 1 245 ? -16.838 -28.554 31.759 1.00 138.20 ? 245 ARG B CA 1 +ATOM 3710 C C . ARG B 1 245 ? -16.857 -30.053 32.058 1.00 148.20 ? 245 ARG B C 1 +ATOM 3711 O O . ARG B 1 245 ? -15.960 -30.565 32.732 1.00 167.54 ? 245 ARG B O 1 +ATOM 3712 C CB . ARG B 1 245 ? -17.615 -27.844 32.855 1.00 151.70 ? 245 ARG B CB 1 +ATOM 3713 C CG . ARG B 1 245 ? -16.994 -28.016 34.244 1.00 150.67 ? 245 ARG B CG 1 +ATOM 3714 C CD . ARG B 1 245 ? -17.729 -27.206 35.322 1.00 173.13 ? 245 ARG B CD 1 +ATOM 3715 N NE . ARG B 1 245 ? -17.051 -25.933 35.584 1.00 192.84 ? 245 ARG B NE 1 +ATOM 3716 C CZ . ARG B 1 245 ? -15.882 -25.810 36.214 1.00 181.36 ? 245 ARG B CZ 1 +ATOM 3717 N NH1 . ARG B 1 245 ? -15.224 -26.878 36.626 1.00 169.11 ? 245 ARG B NH1 1 +ATOM 3718 N NH2 . ARG B 1 245 ? -15.355 -24.609 36.417 1.00 194.93 ? 245 ARG B NH2 1 +ATOM 3719 N N . GLN B 1 246 ? -17.877 -30.756 31.571 1.00 148.22 ? 246 GLN B N 1 +ATOM 3720 C CA . GLN B 1 246 ? -18.021 -32.184 31.864 1.00 154.20 ? 246 GLN B CA 1 +ATOM 3721 C C . GLN B 1 246 ? -17.382 -33.057 30.788 1.00 156.31 ? 246 GLN B C 1 +ATOM 3722 O O . GLN B 1 246 ? -17.733 -34.225 30.634 1.00 176.47 ? 246 GLN B O 1 +ATOM 3723 C CB . GLN B 1 246 ? -19.497 -32.543 32.050 1.00 155.96 ? 246 GLN B CB 1 +ATOM 3724 C CG . GLN B 1 246 ? -20.116 -31.861 33.263 1.00 159.89 ? 246 GLN B CG 1 +ATOM 3725 C CD . GLN B 1 246 ? -19.707 -32.461 34.603 1.00 183.30 ? 246 GLN B CD 1 +ATOM 3726 O OE1 . GLN B 1 246 ? -18.526 -32.680 34.873 1.00 179.02 ? 246 GLN B OE1 1 +ATOM 3727 N NE2 . GLN B 1 246 ? -20.688 -32.670 35.477 1.00 213.40 ? 246 GLN B NE2 1 +ATOM 3728 N N . ASN B 1 247 ? -16.452 -32.470 30.040 1.00 148.80 ? 247 ASN B N 1 +ATOM 3729 C CA . ASN B 1 247 ? -15.564 -33.207 29.137 1.00 147.63 ? 247 ASN B CA 1 +ATOM 3730 C C . ASN B 1 247 ? -15.054 -34.505 29.768 1.00 149.72 ? 247 ASN B C 1 +ATOM 3731 O O . ASN B 1 247 ? -14.701 -34.527 30.949 1.00 152.55 ? 247 ASN B O 1 +ATOM 3732 C CB . ASN B 1 247 ? -14.364 -32.323 28.785 1.00 137.53 ? 247 ASN B CB 1 +ATOM 3733 C CG . ASN B 1 247 ? -13.743 -32.667 27.458 1.00 127.23 ? 247 ASN B CG 1 +ATOM 3734 O OD1 . ASN B 1 247 ? -12.654 -33.254 27.398 1.00 120.26 ? 247 ASN B OD1 1 +ATOM 3735 N ND2 . ASN B 1 247 ? -14.442 -32.327 26.380 1.00 131.05 ? 247 ASN B ND2 1 +ATOM 3736 N N . ASP B 1 248 ? -15.034 -35.585 28.983 1.00 156.87 ? 248 ASP B N 1 +ATOM 3737 C CA . ASP B 1 248 ? -14.634 -36.919 29.481 1.00 164.42 ? 248 ASP B CA 1 +ATOM 3738 C C . ASP B 1 248 ? -13.280 -36.869 30.189 1.00 157.34 ? 248 ASP B C 1 +ATOM 3739 O O . ASP B 1 248 ? -13.095 -37.436 31.273 1.00 171.51 ? 248 ASP B O 1 +ATOM 3740 C CB . ASP B 1 248 ? -14.546 -37.927 28.325 1.00 154.58 ? 248 ASP B CB 1 +ATOM 3741 C CG . ASP B 1 248 ? -15.907 -38.313 27.768 1.00 150.85 ? 248 ASP B CG 1 +ATOM 3742 O OD1 . ASP B 1 248 ? -16.863 -38.465 28.550 1.00 146.48 ? 248 ASP B OD1 1 +ATOM 3743 O OD2 . ASP B 1 248 ? -16.011 -38.487 26.537 1.00 162.02 ? 248 ASP B OD2 1 +ATOM 3744 N N . ILE B 1 249 ? -12.335 -36.192 29.549 1.00 147.54 ? 249 ILE B N 1 +ATOM 3745 C CA . ILE B 1 249 ? -10.973 -36.122 30.038 1.00 144.61 ? 249 ILE B CA 1 +ATOM 3746 C C . ILE B 1 249 ? -10.943 -35.321 31.339 1.00 127.33 ? 249 ILE B C 1 +ATOM 3747 O O . ILE B 1 249 ? -10.376 -35.771 32.351 1.00 171.43 ? 249 ILE B O 1 +ATOM 3748 C CB . ILE B 1 249 ? -10.041 -35.481 28.983 1.00 144.60 ? 249 ILE B CB 1 +ATOM 3749 C CG1 . ILE B 1 249 ? -9.987 -36.354 27.716 1.00 130.01 ? 249 ILE B CG1 1 +ATOM 3750 C CG2 . ILE B 1 249 ? -8.635 -35.315 29.544 1.00 164.30 ? 249 ILE B CG2 1 +ATOM 3751 C CD1 . ILE B 1 249 ? -9.527 -35.620 26.477 1.00 114.15 ? 249 ILE B CD1 1 +ATOM 3752 N N . LEU B 1 250 ? -11.568 -34.149 31.313 1.00 91.80 ? 250 LEU B N 1 +ATOM 3753 C CA . LEU B 1 250 ? -11.563 -33.261 32.470 1.00 102.34 ? 250 LEU B CA 1 +ATOM 3754 C C . LEU B 1 250 ? -12.184 -33.905 33.710 1.00 126.01 ? 250 LEU B C 1 +ATOM 3755 O O . LEU B 1 250 ? -11.716 -33.692 34.834 1.00 111.79 ? 250 LEU B O 1 +ATOM 3756 C CB . LEU B 1 250 ? -12.290 -31.958 32.147 1.00 90.53 ? 250 LEU B CB 1 +ATOM 3757 C CG . LEU B 1 250 ? -11.461 -30.930 31.373 1.00 87.69 ? 250 LEU B CG 1 +ATOM 3758 C CD1 . LEU B 1 250 ? -12.317 -29.788 30.833 1.00 74.39 ? 250 LEU B CD1 1 +ATOM 3759 C CD2 . LEU B 1 250 ? -10.353 -30.373 32.252 1.00 88.21 ? 250 LEU B CD2 1 +ATOM 3760 N N . VAL B 1 251 ? -13.253 -34.671 33.507 1.00 155.46 ? 251 VAL B N 1 +ATOM 3761 C CA . VAL B 1 251 ? -13.914 -35.359 34.623 1.00 163.90 ? 251 VAL B CA 1 +ATOM 3762 C C . VAL B 1 251 ? -13.111 -36.577 35.081 1.00 156.44 ? 251 VAL B C 1 +ATOM 3763 O O . VAL B 1 251 ? -13.239 -37.020 36.227 1.00 156.12 ? 251 VAL B O 1 +ATOM 3764 C CB . VAL B 1 251 ? -15.371 -35.775 34.285 1.00 143.99 ? 251 VAL B CB 1 +ATOM 3765 C CG1 . VAL B 1 251 ? -16.177 -34.560 33.828 1.00 126.29 ? 251 VAL B CG1 1 +ATOM 3766 C CG2 . VAL B 1 251 ? -15.409 -36.893 33.248 1.00 129.80 ? 251 VAL B CG2 1 +ATOM 3767 N N . LYS B 1 252 ? -12.310 -37.130 34.177 1.00 132.43 ? 252 LYS B N 1 +ATOM 3768 C CA . LYS B 1 252 ? -11.453 -38.262 34.513 1.00 137.11 ? 252 LYS B CA 1 +ATOM 3769 C C . LYS B 1 252 ? -10.355 -37.817 35.484 1.00 156.24 ? 252 LYS B C 1 +ATOM 3770 O O . LYS B 1 252 ? -10.116 -38.461 36.515 1.00 178.47 ? 252 LYS B O 1 +ATOM 3771 C CB . LYS B 1 252 ? -10.868 -38.849 33.230 1.00 133.05 ? 252 LYS B CB 1 +ATOM 3772 C CG . LYS B 1 252 ? -9.912 -40.012 33.422 1.00 128.44 ? 252 LYS B CG 1 +ATOM 3773 C CD . LYS B 1 252 ? -9.375 -40.477 32.072 1.00 141.98 ? 252 LYS B CD 1 +ATOM 3774 C CE . LYS B 1 252 ? -7.862 -40.657 32.102 1.00 160.92 ? 252 LYS B CE 1 +ATOM 3775 N NZ . LYS B 1 252 ? -7.280 -40.850 30.744 1.00 150.66 ? 252 LYS B NZ 1 +ATOM 3776 N N . TYR B 1 253 ? -9.732 -36.681 35.180 1.00 179.09 ? 253 TYR B N 1 +ATOM 3777 C CA . TYR B 1 253 ? -8.659 -36.137 36.021 1.00 185.65 ? 253 TYR B CA 1 +ATOM 3778 C C . TYR B 1 253 ? -9.224 -35.471 37.265 1.00 184.62 ? 253 TYR B C 1 +ATOM 3779 O O . TYR B 1 253 ? -8.587 -35.480 38.325 1.00 219.13 ? 253 TYR B O 1 +ATOM 3780 C CB . TYR B 1 253 ? -7.780 -35.160 35.232 1.00 171.71 ? 253 TYR B CB 1 +ATOM 3781 C CG . TYR B 1 253 ? -6.896 -35.885 34.239 1.00 153.89 ? 253 TYR B CG 1 +ATOM 3782 C CD1 . TYR B 1 253 ? -7.360 -36.159 32.960 1.00 141.70 ? 253 TYR B CD1 1 +ATOM 3783 C CD2 . TYR B 1 253 ? -5.633 -36.365 34.596 1.00 144.21 ? 253 TYR B CD2 1 +ATOM 3784 C CE1 . TYR B 1 253 ? -6.592 -36.847 32.036 1.00 114.26 ? 253 TYR B CE1 1 +ATOM 3785 C CE2 . TYR B 1 253 ? -4.858 -37.052 33.673 1.00 149.93 ? 253 TYR B CE2 1 +ATOM 3786 C CZ . TYR B 1 253 ? -5.353 -37.302 32.400 1.00 133.14 ? 253 TYR B CZ 1 +ATOM 3787 O OH . TYR B 1 253 ? -4.593 -37.997 31.485 1.00 130.28 ? 253 TYR B OH 1 +ATOM 3788 N N . ARG B 1 254 ? -10.417 -34.895 37.130 1.00 149.19 ? 254 ARG B N 1 +ATOM 3789 C CA . ARG B 1 254 ? -11.166 -34.410 38.284 1.00 165.63 ? 254 ARG B CA 1 +ATOM 3790 C C . ARG B 1 254 ? -11.414 -35.557 39.268 1.00 183.64 ? 254 ARG B C 1 +ATOM 3791 O O . ARG B 1 254 ? -11.310 -35.374 40.492 1.00 201.96 ? 254 ARG B O 1 +ATOM 3792 C CB . ARG B 1 254 ? -12.509 -33.808 37.852 1.00 161.53 ? 254 ARG B CB 1 +ATOM 3793 C CG . ARG B 1 254 ? -13.297 -33.175 38.993 1.00 156.34 ? 254 ARG B CG 1 +ATOM 3794 C CD . ARG B 1 254 ? -14.402 -32.236 38.515 1.00 146.14 ? 254 ARG B CD 1 +ATOM 3795 N NE . ARG B 1 254 ? -13.923 -31.032 37.830 1.00 154.62 ? 254 ARG B NE 1 +ATOM 3796 C CZ . ARG B 1 254 ? -14.023 -30.792 36.521 1.00 141.97 ? 254 ARG B CZ 1 +ATOM 3797 N NH1 . ARG B 1 254 ? -14.572 -31.682 35.707 1.00 112.19 ? 254 ARG B NH1 1 +ATOM 3798 N NH2 . ARG B 1 254 ? -13.563 -29.647 36.023 1.00 140.99 ? 254 ARG B NH2 1 +ATOM 3799 N N . HIS B 1 255 ? -11.725 -36.736 38.724 1.00 178.45 ? 255 HIS B N 1 +ATOM 3800 C CA . HIS B 1 255 ? -11.988 -37.930 39.537 1.00 201.83 ? 255 HIS B CA 1 +ATOM 3801 C C . HIS B 1 255 ? -10.739 -38.465 40.236 1.00 182.98 ? 255 HIS B C 1 +ATOM 3802 O O . HIS B 1 255 ? -10.819 -38.956 41.364 1.00 199.16 ? 255 HIS B O 1 +ATOM 3803 C CB . HIS B 1 255 ? -12.629 -39.041 38.694 1.00 203.19 ? 255 HIS B CB 1 +ATOM 3804 C CG . HIS B 1 255 ? -14.094 -39.234 38.952 1.00 216.39 ? 255 HIS B CG 1 +ATOM 3805 N ND1 . HIS B 1 255 ? -15.055 -38.362 38.483 1.00 208.02 ? 255 HIS B ND1 1 +ATOM 3806 C CD2 . HIS B 1 255 ? -14.761 -40.198 39.631 1.00 195.13 ? 255 HIS B CD2 1 +ATOM 3807 C CE1 . HIS B 1 255 ? -16.249 -38.780 38.866 1.00 195.14 ? 255 HIS B CE1 1 +ATOM 3808 N NE2 . HIS B 1 255 ? -16.098 -39.891 39.566 1.00 191.64 ? 255 HIS B NE2 1 +ATOM 3809 N N . MET B 1 256 ? -9.586 -38.340 39.591 1.00 165.29 ? 256 MET B N 1 +ATOM 3810 C CA . MET B 1 256 ? -8.338 -38.782 40.213 1.00 154.65 ? 256 MET B CA 1 +ATOM 3811 C C . MET B 1 256 ? -7.945 -37.905 41.421 1.00 124.99 ? 256 MET B C 1 +ATOM 3812 O O . MET B 1 256 ? -7.268 -38.382 42.343 1.00 139.02 ? 256 MET B O 1 +ATOM 3813 C CB . MET B 1 256 ? -7.207 -38.836 39.178 1.00 177.03 ? 256 MET B CB 1 +ATOM 3814 C CG . MET B 1 256 ? -7.548 -39.652 37.934 1.00 182.88 ? 256 MET B CG 1 +ATOM 3815 S SD . MET B 1 256 ? -6.142 -40.198 36.948 1.00 188.79 ? 256 MET B SD 1 +ATOM 3816 C CE . MET B 1 256 ? -5.399 -41.398 38.062 1.00 142.77 ? 256 MET B CE 1 +ATOM 3817 N N . SER B 1 257 ? -8.434 -36.665 41.451 1.00 111.31 ? 257 SER B N 1 +ATOM 3818 C CA . SER B 1 257 ? -8.297 -35.779 42.613 1.00 122.37 ? 257 SER B CA 1 +ATOM 3819 C C . SER B 1 257 ? -9.270 -36.134 43.739 1.00 119.36 ? 257 SER B C 1 +ATOM 3820 O O . SER B 1 257 ? -8.932 -36.953 44.603 1.00 151.40 ? 257 SER B O 1 +ATOM 3821 C CB . SER B 1 257 ? -8.530 -34.327 42.199 1.00 138.66 ? 257 SER B CB 1 +ATOM 3822 O OG . SER B 1 257 ? -7.919 -34.050 40.941 1.00 142.23 ? 257 SER B OG 1 +ATOM 3823 N N . LEU C 1 2 ? 8.901 -55.089 15.897 1.00 101.35 ? 2 LEU C N 1 +ATOM 3824 C CA . LEU C 1 2 ? 9.392 -55.131 17.318 1.00 116.74 ? 2 LEU C CA 1 +ATOM 3825 C C . LEU C 1 2 ? 10.903 -54.809 17.390 1.00 127.42 ? 2 LEU C C 1 +ATOM 3826 O O . LEU C 1 2 ? 11.767 -55.684 17.645 1.00 87.80 ? 2 LEU C O 1 +ATOM 3827 C CB . LEU C 1 2 ? 9.082 -56.484 17.970 1.00 138.26 ? 2 LEU C CB 1 +ATOM 3828 C CG . LEU C 1 2 ? 7.604 -56.926 18.109 1.00 130.68 ? 2 LEU C CG 1 +ATOM 3829 C CD1 . LEU C 1 2 ? 7.549 -58.309 18.756 1.00 140.19 ? 2 LEU C CD1 1 +ATOM 3830 C CD2 . LEU C 1 2 ? 6.717 -55.948 18.879 1.00 120.69 ? 2 LEU C CD2 1 +ATOM 3831 N N . THR C 1 3 ? 11.199 -53.576 16.970 1.00 143.96 ? 3 THR C N 1 +ATOM 3832 C CA . THR C 1 3 ? 12.464 -52.889 17.239 1.00 131.79 ? 3 THR C CA 1 +ATOM 3833 C C . THR C 1 3 ? 12.205 -51.402 17.563 1.00 142.44 ? 3 THR C C 1 +ATOM 3834 O O . THR C 1 3 ? 13.124 -50.664 17.931 1.00 179.06 ? 3 THR C O 1 +ATOM 3835 C CB . THR C 1 3 ? 13.448 -52.939 16.051 1.00 115.73 ? 3 THR C CB 1 +ATOM 3836 O OG1 . THR C 1 3 ? 12.960 -52.129 14.974 1.00 70.94 ? 3 THR C OG1 1 +ATOM 3837 C CG2 . THR C 1 3 ? 13.686 -54.383 15.603 1.00 121.53 ? 3 THR C CG2 1 +ATOM 3838 N N . ALA C 1 4 ? 10.963 -50.952 17.400 1.00 129.26 ? 4 ALA C N 1 +ATOM 3839 C CA . ALA C 1 4 ? 10.517 -49.680 17.978 1.00 139.78 ? 4 ALA C CA 1 +ATOM 3840 C C . ALA C 1 4 ? 10.243 -49.886 19.489 1.00 133.64 ? 4 ALA C C 1 +ATOM 3841 O O . ALA C 1 4 ? 10.535 -50.952 20.026 1.00 123.64 ? 4 ALA C O 1 +ATOM 3842 C CB . ALA C 1 4 ? 9.285 -49.163 17.237 1.00 122.67 ? 4 ALA C CB 1 +ATOM 3843 N N . PRO C 1 5 ? 9.765 -48.853 20.206 1.00 140.98 ? 5 PRO C N 1 +ATOM 3844 C CA . PRO C 1 5 ? 9.884 -49.047 21.646 1.00 125.71 ? 5 PRO C CA 1 +ATOM 3845 C C . PRO C 1 5 ? 8.748 -49.915 22.217 1.00 133.21 ? 5 PRO C C 1 +ATOM 3846 O O . PRO C 1 5 ? 7.806 -50.241 21.503 1.00 153.61 ? 5 PRO C O 1 +ATOM 3847 C CB . PRO C 1 5 ? 9.813 -47.623 22.192 1.00 129.26 ? 5 PRO C CB 1 +ATOM 3848 C CG . PRO C 1 5 ? 9.016 -46.855 21.180 1.00 161.02 ? 5 PRO C CG 1 +ATOM 3849 C CD . PRO C 1 5 ? 9.074 -47.593 19.866 1.00 156.60 ? 5 PRO C CD 1 +ATOM 3850 N N . PRO C 1 6 ? 8.881 -50.355 23.474 1.00 129.34 ? 6 PRO C N 1 +ATOM 3851 C CA . PRO C 1 6 ? 7.771 -50.969 24.198 1.00 113.57 ? 6 PRO C CA 1 +ATOM 3852 C C . PRO C 1 6 ? 6.803 -49.930 24.711 1.00 102.93 ? 6 PRO C C 1 +ATOM 3853 O O . PRO C 1 6 ? 7.202 -48.786 24.994 1.00 113.41 ? 6 PRO C O 1 +ATOM 3854 C CB . PRO C 1 6 ? 8.450 -51.698 25.361 1.00 137.18 ? 6 PRO C CB 1 +ATOM 3855 C CG . PRO C 1 6 ? 9.834 -51.149 25.464 1.00 118.78 ? 6 PRO C CG 1 +ATOM 3856 C CD . PRO C 1 6 ? 10.170 -50.442 24.189 1.00 131.65 ? 6 PRO C CD 1 +ATOM 3857 N N . LYS C 1 7 ? 5.544 -50.315 24.861 1.00 86.82 ? 7 LYS C N 1 +ATOM 3858 C CA . LYS C 1 7 ? 4.540 -49.347 25.294 1.00 108.17 ? 7 LYS C CA 1 +ATOM 3859 C C . LYS C 1 7 ? 4.300 -49.349 26.811 1.00 100.32 ? 7 LYS C C 1 +ATOM 3860 O O . LYS C 1 7 ? 4.766 -50.247 27.529 1.00 53.74 ? 7 LYS C O 1 +ATOM 3861 C CB . LYS C 1 7 ? 3.225 -49.554 24.547 1.00 123.23 ? 7 LYS C CB 1 +ATOM 3862 C CG . LYS C 1 7 ? 3.284 -49.240 23.066 1.00 126.60 ? 7 LYS C CG 1 +ATOM 3863 C CD . LYS C 1 7 ? 3.315 -50.491 22.191 1.00 116.90 ? 7 LYS C CD 1 +ATOM 3864 C CE . LYS C 1 7 ? 3.056 -50.137 20.739 1.00 112.50 ? 7 LYS C CE 1 +ATOM 3865 N NZ . LYS C 1 7 ? 3.725 -51.072 19.799 1.00 106.69 ? 7 LYS C NZ 1 +ATOM 3866 N N . GLU C 1 8 ? 3.569 -48.320 27.268 1.00 107.25 ? 8 GLU C N 1 +ATOM 3867 C CA . GLU C 1 8 ? 3.452 -47.989 28.689 1.00 104.17 ? 8 GLU C CA 1 +ATOM 3868 C C . GLU C 1 8 ? 2.752 -49.086 29.471 1.00 88.16 ? 8 GLU C C 1 +ATOM 3869 O O . GLU C 1 8 ? 1.591 -49.388 29.240 1.00 82.76 ? 8 GLU C O 1 +ATOM 3870 C CB . GLU C 1 8 ? 2.749 -46.603 28.925 1.00 117.40 ? 8 GLU C CB 1 +ATOM 3871 C CG . GLU C 1 8 ? 1.231 -46.533 28.867 1.00 141.34 ? 8 GLU C CG 1 +ATOM 3872 C CD . GLU C 1 8 ? 0.661 -45.184 29.333 1.00 142.29 ? 8 GLU C CD 1 +ATOM 3873 O OE1 . GLU C 1 8 ? 0.959 -44.740 30.457 1.00 144.23 ? 8 GLU C OE1 1 +ATOM 3874 O OE2 . GLU C 1 8 ? -0.133 -44.577 28.600 1.00 126.63 ? 8 GLU C OE2 1 +ATOM 3875 N N . ALA C 1 9 ? 3.475 -49.666 30.414 1.00 81.99 ? 9 ALA C N 1 +ATOM 3876 C CA . ALA C 1 9 ? 2.896 -50.562 31.393 1.00 78.93 ? 9 ALA C CA 1 +ATOM 3877 C C . ALA C 1 9 ? 2.525 -49.786 32.668 1.00 94.14 ? 9 ALA C C 1 +ATOM 3878 O O . ALA C 1 9 ? 3.405 -49.268 33.363 1.00 102.91 ? 9 ALA C O 1 +ATOM 3879 C CB . ALA C 1 9 ? 3.896 -51.649 31.704 1.00 79.23 ? 9 ALA C CB 1 +ATOM 3880 N N . ALA C 1 10 ? 1.224 -49.731 32.967 1.00 85.48 ? 10 ALA C N 1 +ATOM 3881 C CA . ALA C 1 10 ? 0.652 -48.901 34.043 1.00 89.63 ? 10 ALA C CA 1 +ATOM 3882 C C . ALA C 1 10 ? 0.410 -47.477 33.560 1.00 91.52 ? 10 ALA C C 1 +ATOM 3883 O O . ALA C 1 10 ? 1.008 -47.029 32.600 1.00 72.15 ? 10 ALA C O 1 +ATOM 3884 C CB . ALA C 1 10 ? 1.510 -48.909 35.319 1.00 76.75 ? 10 ALA C CB 1 +ATOM 3885 N N . ARG C 1 11 ? -0.477 -46.773 34.253 1.00 115.36 ? 11 ARG C N 1 +ATOM 3886 C CA . ARG C 1 11 ? -0.848 -45.400 33.894 1.00 135.13 ? 11 ARG C CA 1 +ATOM 3887 C C . ARG C 1 11 ? -0.149 -44.415 34.828 1.00 122.80 ? 11 ARG C C 1 +ATOM 3888 O O . ARG C 1 11 ? 0.123 -44.750 35.970 1.00 123.47 ? 11 ARG C O 1 +ATOM 3889 C CB . ARG C 1 11 ? -2.373 -45.204 34.017 1.00 166.65 ? 11 ARG C CB 1 +ATOM 3890 C CG . ARG C 1 11 ? -2.922 -45.308 35.436 1.00 170.67 ? 11 ARG C CG 1 +ATOM 3891 C CD . ARG C 1 11 ? -4.381 -45.767 35.439 1.00 178.87 ? 11 ARG C CD 1 +ATOM 3892 N NE . ARG C 1 11 ? -4.533 -47.131 35.948 1.00 187.76 ? 11 ARG C NE 1 +ATOM 3893 C CZ . ARG C 1 11 ? -5.704 -47.748 36.095 1.00 160.49 ? 11 ARG C CZ 1 +ATOM 3894 N NH1 . ARG C 1 11 ? -6.829 -47.105 35.818 1.00 170.21 ? 11 ARG C NH1 1 +ATOM 3895 N NH2 . ARG C 1 11 ? -5.753 -48.998 36.535 1.00 133.49 ? 11 ARG C NH2 1 +ATOM 3896 N N . PRO C 1 12 ? 0.103 -43.177 34.359 1.00 97.94 ? 12 PRO C N 1 +ATOM 3897 C CA . PRO C 1 12 ? 0.461 -42.142 35.305 1.00 77.81 ? 12 PRO C CA 1 +ATOM 3898 C C . PRO C 1 12 ? -0.701 -41.842 36.245 1.00 78.70 ? 12 PRO C C 1 +ATOM 3899 O O . PRO C 1 12 ? -1.751 -41.377 35.819 1.00 75.78 ? 12 PRO C O 1 +ATOM 3900 C CB . PRO C 1 12 ? 0.771 -40.926 34.412 1.00 82.69 ? 12 PRO C CB 1 +ATOM 3901 C CG . PRO C 1 12 ? 0.879 -41.438 33.028 1.00 89.28 ? 12 PRO C CG 1 +ATOM 3902 C CD . PRO C 1 12 ? -0.002 -42.650 32.989 1.00 106.46 ? 12 PRO C CD 1 +ATOM 3903 N N . THR C 1 13 ? -0.520 -42.155 37.518 1.00 88.96 ? 13 THR C N 1 +ATOM 3904 C CA . THR C 1 13 ? -1.413 -41.683 38.568 1.00 103.40 ? 13 THR C CA 1 +ATOM 3905 C C . THR C 1 13 ? -0.852 -40.417 39.221 1.00 95.28 ? 13 THR C C 1 +ATOM 3906 O O . THR C 1 13 ? 0.355 -40.171 39.141 1.00 125.14 ? 13 THR C O 1 +ATOM 3907 C CB . THR C 1 13 ? -1.562 -42.778 39.634 1.00 132.38 ? 13 THR C CB 1 +ATOM 3908 O OG1 . THR C 1 13 ? -2.606 -42.419 40.543 1.00 209.92 ? 13 THR C OG1 1 +ATOM 3909 C CG2 . THR C 1 13 ? -0.221 -43.045 40.410 1.00 114.34 ? 13 THR C CG2 1 +ATOM 3910 N N . LEU C 1 14 ? -1.672 -39.646 39.923 1.00 79.16 ? 14 LEU C N 1 +ATOM 3911 C CA . LEU C 1 14 ? -1.075 -38.637 40.807 1.00 81.77 ? 14 LEU C CA 1 +ATOM 3912 C C . LEU C 1 14 ? -0.454 -39.311 42.045 1.00 80.80 ? 14 LEU C C 1 +ATOM 3913 O O . LEU C 1 14 ? -0.747 -40.450 42.327 1.00 71.03 ? 14 LEU C O 1 +ATOM 3914 C CB . LEU C 1 14 ? -2.040 -37.508 41.164 1.00 80.09 ? 14 LEU C CB 1 +ATOM 3915 C CG . LEU C 1 14 ? -3.375 -37.868 41.766 1.00 95.32 ? 14 LEU C CG 1 +ATOM 3916 C CD1 . LEU C 1 14 ? -3.834 -36.794 42.740 1.00 97.31 ? 14 LEU C CD1 1 +ATOM 3917 C CD2 . LEU C 1 14 ? -4.376 -38.017 40.646 1.00 116.48 ? 14 LEU C CD2 1 +ATOM 3918 N N . MET C 1 15 ? 0.484 -38.658 42.723 1.00 105.46 ? 15 MET C N 1 +ATOM 3919 C CA . MET C 1 15 ? 1.480 -39.395 43.529 1.00 112.41 ? 15 MET C CA 1 +ATOM 3920 C C . MET C 1 15 ? 0.825 -40.026 44.768 1.00 90.68 ? 15 MET C C 1 +ATOM 3921 O O . MET C 1 15 ? 0.220 -39.320 45.572 1.00 93.94 ? 15 MET C O 1 +ATOM 3922 C CB . MET C 1 15 ? 2.671 -38.486 43.942 1.00 138.85 ? 15 MET C CB 1 +ATOM 3923 C CG . MET C 1 15 ? 3.986 -39.245 44.130 1.00 144.80 ? 15 MET C CG 1 +ATOM 3924 S SD . MET C 1 15 ? 5.200 -38.712 45.367 1.00 158.02 ? 15 MET C SD 1 +ATOM 3925 C CE . MET C 1 15 ? 4.262 -37.780 46.584 1.00 121.52 ? 15 MET C CE 1 +ATOM 3926 N N . PRO C 1 16 ? 0.995 -41.342 44.946 1.00 66.60 ? 16 PRO C N 1 +ATOM 3927 C CA . PRO C 1 16 ? 0.298 -42.145 45.939 1.00 67.08 ? 16 PRO C CA 1 +ATOM 3928 C C . PRO C 1 16 ? 0.688 -41.800 47.373 1.00 80.96 ? 16 PRO C C 1 +ATOM 3929 O O . PRO C 1 16 ? 1.483 -42.493 48.002 1.00 98.33 ? 16 PRO C O 1 +ATOM 3930 C CB . PRO C 1 16 ? 0.703 -43.577 45.590 1.00 71.23 ? 16 PRO C CB 1 +ATOM 3931 C CG . PRO C 1 16 ? 1.990 -43.422 44.859 1.00 87.69 ? 16 PRO C CG 1 +ATOM 3932 C CD . PRO C 1 16 ? 1.846 -42.162 44.077 1.00 79.67 ? 16 PRO C CD 1 +ATOM 3933 N N . ARG C 1 17 ? 0.067 -40.761 47.908 1.00 107.31 ? 17 ARG C N 1 +ATOM 3934 C CA . ARG C 1 17 ? 0.195 -40.428 49.324 1.00 126.88 ? 17 ARG C CA 1 +ATOM 3935 C C . ARG C 1 17 ? -0.860 -41.186 50.128 1.00 146.64 ? 17 ARG C C 1 +ATOM 3936 O O . ARG C 1 17 ? -1.958 -41.423 49.630 1.00 171.72 ? 17 ARG C O 1 +ATOM 3937 C CB . ARG C 1 17 ? 0.018 -38.924 49.507 1.00 148.84 ? 17 ARG C CB 1 +ATOM 3938 C CG . ARG C 1 17 ? 1.305 -38.148 49.331 1.00 159.03 ? 17 ARG C CG 1 +ATOM 3939 C CD . ARG C 1 17 ? 1.066 -36.663 49.088 1.00 150.97 ? 17 ARG C CD 1 +ATOM 3940 N NE . ARG C 1 17 ? 0.614 -36.395 47.723 1.00 121.02 ? 17 ARG C NE 1 +ATOM 3941 C CZ . ARG C 1 17 ? 0.245 -35.193 47.287 1.00 118.25 ? 17 ARG C CZ 1 +ATOM 3942 N NH1 . ARG C 1 17 ? 0.219 -34.162 48.132 1.00 109.65 ? 17 ARG C NH1 1 +ATOM 3943 N NH2 . ARG C 1 17 ? -0.080 -35.018 46.006 1.00 107.89 ? 17 ARG C NH2 1 +ATOM 3944 N N . ALA C 1 18 ? -0.541 -41.569 51.362 1.00 152.51 ? 18 ALA C N 1 +ATOM 3945 C CA . ALA C 1 18 ? -1.469 -42.370 52.175 1.00 144.68 ? 18 ALA C CA 1 +ATOM 3946 C C . ALA C 1 18 ? -2.007 -41.615 53.404 1.00 148.19 ? 18 ALA C C 1 +ATOM 3947 O O . ALA C 1 18 ? -2.706 -40.601 53.256 1.00 176.23 ? 18 ALA C O 1 +ATOM 3948 C CB . ALA C 1 18 ? -0.832 -43.693 52.580 1.00 137.47 ? 18 ALA C CB 1 +ATOM 3949 N N . GLN C 1 19 ? -1.730 -42.125 54.603 1.00 119.33 ? 19 GLN C N 1 +ATOM 3950 C CA . GLN C 1 19 ? -2.530 -41.768 55.777 1.00 147.86 ? 19 GLN C CA 1 +ATOM 3951 C C . GLN C 1 19 ? -2.262 -40.334 56.221 1.00 137.85 ? 19 GLN C C 1 +ATOM 3952 O O . GLN C 1 19 ? -3.189 -39.545 56.473 1.00 98.61 ? 19 GLN C O 1 +ATOM 3953 C CB . GLN C 1 19 ? -2.235 -42.736 56.930 1.00 177.38 ? 19 GLN C CB 1 +ATOM 3954 C CG . GLN C 1 19 ? -3.112 -42.538 58.165 1.00 185.30 ? 19 GLN C CG 1 +ATOM 3955 C CD . GLN C 1 19 ? -4.602 -42.584 57.854 1.00 151.62 ? 19 GLN C CD 1 +ATOM 3956 O OE1 . GLN C 1 19 ? -5.132 -43.622 57.458 1.00 126.95 ? 19 GLN C OE1 1 +ATOM 3957 N NE2 . GLN C 1 19 ? -5.276 -41.451 58.008 1.00 133.89 ? 19 GLN C NE2 1 +ATOM 3958 N N . SER C 1 20 ? -0.975 -40.032 56.361 1.00 135.83 ? 20 SER C N 1 +ATOM 3959 C CA . SER C 1 20 ? -0.510 -38.688 56.651 1.00 138.15 ? 20 SER C CA 1 +ATOM 3960 C C . SER C 1 20 ? -1.274 -37.649 55.818 1.00 147.48 ? 20 SER C C 1 +ATOM 3961 O O . SER C 1 20 ? -1.787 -36.666 56.355 1.00 123.38 ? 20 SER C O 1 +ATOM 3962 C CB . SER C 1 20 ? 0.994 -38.610 56.362 1.00 133.25 ? 20 SER C CB 1 +ATOM 3963 O OG . SER C 1 20 ? 1.691 -39.666 57.007 1.00 136.13 ? 20 SER C OG 1 +ATOM 3964 N N . TYR C 1 21 ? -1.342 -37.884 54.507 1.00 165.47 ? 21 TYR C N 1 +ATOM 3965 C CA . TYR C 1 21 ? -2.076 -37.019 53.581 1.00 163.51 ? 21 TYR C CA 1 +ATOM 3966 C C . TYR C 1 21 ? -3.545 -36.847 53.973 1.00 162.02 ? 21 TYR C C 1 +ATOM 3967 O O . TYR C 1 21 ? -4.062 -35.718 54.031 1.00 162.26 ? 21 TYR C O 1 +ATOM 3968 C CB . TYR C 1 21 ? -1.997 -37.578 52.157 1.00 147.73 ? 21 TYR C CB 1 +ATOM 3969 C CG . TYR C 1 21 ? -2.694 -36.714 51.127 1.00 147.50 ? 21 TYR C CG 1 +ATOM 3970 C CD1 . TYR C 1 21 ? -2.113 -35.530 50.680 1.00 141.53 ? 21 TYR C CD1 1 +ATOM 3971 C CD2 . TYR C 1 21 ? -3.947 -37.063 50.624 1.00 143.17 ? 21 TYR C CD2 1 +ATOM 3972 C CE1 . TYR C 1 21 ? -2.748 -34.730 49.754 1.00 140.58 ? 21 TYR C CE1 1 +ATOM 3973 C CE2 . TYR C 1 21 ? -4.592 -36.268 49.689 1.00 136.28 ? 21 TYR C CE2 1 +ATOM 3974 C CZ . TYR C 1 21 ? -3.988 -35.105 49.259 1.00 143.55 ? 21 TYR C CZ 1 +ATOM 3975 O OH . TYR C 1 21 ? -4.595 -34.294 48.331 1.00 147.78 ? 21 TYR C OH 1 +ATOM 3976 N N . LYS C 1 22 ? -4.218 -37.966 54.224 1.00 142.94 ? 22 LYS C N 1 +ATOM 3977 C CA . LYS C 1 22 ? -5.635 -37.946 54.554 1.00 141.97 ? 22 LYS C CA 1 +ATOM 3978 C C . LYS C 1 22 ? -5.911 -37.127 55.811 1.00 131.23 ? 22 LYS C C 1 +ATOM 3979 O O . LYS C 1 22 ? -6.914 -36.407 55.893 1.00 124.94 ? 22 LYS C O 1 +ATOM 3980 C CB . LYS C 1 22 ? -6.151 -39.374 54.730 1.00 148.93 ? 22 LYS C CB 1 +ATOM 3981 C CG . LYS C 1 22 ? -6.637 -40.008 53.441 1.00 151.77 ? 22 LYS C CG 1 +ATOM 3982 C CD . LYS C 1 22 ? -8.073 -39.559 53.138 1.00 170.73 ? 22 LYS C CD 1 +ATOM 3983 C CE . LYS C 1 22 ? -9.065 -40.671 53.510 1.00 188.90 ? 22 LYS C CE 1 +ATOM 3984 N NZ . LYS C 1 22 ? -8.881 -41.877 52.659 1.00 197.67 ? 22 LYS C NZ 1 +ATOM 3985 N N . ASP C 1 23 ? -5.046 -37.286 56.807 1.00 133.90 ? 23 ASP C N 1 +ATOM 3986 C CA . ASP C 1 23 ? -5.130 -36.490 58.031 1.00 149.48 ? 23 ASP C CA 1 +ATOM 3987 C C . ASP C 1 23 ? -4.903 -35.016 57.718 1.00 134.67 ? 23 ASP C C 1 +ATOM 3988 O O . ASP C 1 23 ? -5.618 -34.144 58.223 1.00 137.93 ? 23 ASP C O 1 +ATOM 3989 C CB . ASP C 1 23 ? -4.089 -36.969 59.053 1.00 151.28 ? 23 ASP C CB 1 +ATOM 3990 C CG . ASP C 1 23 ? -4.392 -38.341 59.582 1.00 162.38 ? 23 ASP C CG 1 +ATOM 3991 O OD1 . ASP C 1 23 ? -5.579 -38.607 59.860 1.00 193.92 ? 23 ASP C OD1 1 +ATOM 3992 O OD2 . ASP C 1 23 ? -3.447 -39.145 59.740 1.00 180.56 ? 23 ASP C OD2 1 +ATOM 3993 N N . LEU C 1 24 ? -3.883 -34.755 56.907 1.00 124.59 ? 24 LEU C N 1 +ATOM 3994 C CA . LEU C 1 24 ? -3.425 -33.396 56.629 1.00 149.87 ? 24 LEU C CA 1 +ATOM 3995 C C . LEU C 1 24 ? -4.487 -32.587 55.880 1.00 159.58 ? 24 LEU C C 1 +ATOM 3996 O O . LEU C 1 24 ? -4.628 -31.367 56.096 1.00 147.30 ? 24 LEU C O 1 +ATOM 3997 C CB . LEU C 1 24 ? -2.126 -33.448 55.811 1.00 148.48 ? 24 LEU C CB 1 +ATOM 3998 C CG . LEU C 1 24 ? -1.473 -32.117 55.402 1.00 137.39 ? 24 LEU C CG 1 +ATOM 3999 C CD1 . LEU C 1 24 ? -0.558 -31.589 56.500 1.00 120.91 ? 24 LEU C CD1 1 +ATOM 4000 C CD2 . LEU C 1 24 ? -0.704 -32.295 54.102 1.00 134.06 ? 24 LEU C CD2 1 +ATOM 4001 N N . THR C 1 25 ? -5.224 -33.266 55.001 1.00 172.90 ? 25 THR C N 1 +ATOM 4002 C CA . THR C 1 25 ? -6.242 -32.609 54.173 1.00 187.16 ? 25 THR C CA 1 +ATOM 4003 C C . THR C 1 25 ? -7.509 -32.287 54.962 1.00 202.63 ? 25 THR C C 1 +ATOM 4004 O O . THR C 1 25 ? -8.017 -31.159 54.906 1.00 196.02 ? 25 THR C O 1 +ATOM 4005 C CB . THR C 1 25 ? -6.623 -33.474 52.956 1.00 170.79 ? 25 THR C CB 1 +ATOM 4006 O OG1 . THR C 1 25 ? -6.831 -34.828 53.369 1.00 153.21 ? 25 THR C OG1 1 +ATOM 4007 C CG2 . THR C 1 25 ? -5.515 -33.434 51.922 1.00 186.29 ? 25 THR C CG2 1 +ATOM 4008 N N . HIS C 1 26 ? -7.980 -33.267 55.732 1.00 210.52 ? 26 HIS C N 1 +ATOM 4009 C CA . HIS C 1 26 ? -9.205 -33.128 56.522 1.00 185.74 ? 26 HIS C CA 1 +ATOM 4010 C C . HIS C 1 26 ? -8.943 -32.452 57.882 1.00 157.98 ? 26 HIS C C 1 +ATOM 4011 O O . HIS C 1 26 ? -9.559 -32.785 58.889 1.00 118.82 ? 26 HIS C O 1 +ATOM 4012 C CB . HIS C 1 26 ? -9.865 -34.505 56.702 1.00 187.51 ? 26 HIS C CB 1 +ATOM 4013 C CG . HIS C 1 26 ? -10.311 -35.128 55.409 1.00 193.36 ? 26 HIS C CG 1 +ATOM 4014 N ND1 . HIS C 1 26 ? -9.425 -35.583 54.454 1.00 179.19 ? 26 HIS C ND1 1 +ATOM 4015 C CD2 . HIS C 1 26 ? -11.550 -35.334 54.899 1.00 199.98 ? 26 HIS C CD2 1 +ATOM 4016 C CE1 . HIS C 1 26 ? -10.098 -36.072 53.427 1.00 186.44 ? 26 HIS C CE1 1 +ATOM 4017 N NE2 . HIS C 1 26 ? -11.389 -35.924 53.667 1.00 195.26 ? 26 HIS C NE2 1 +ATOM 4018 N N . LEU C 1 27 ? -8.033 -31.486 57.905 1.00 148.95 ? 27 LEU C N 1 +ATOM 4019 C CA . LEU C 1 27 ? -7.802 -30.693 59.103 1.00 135.79 ? 27 LEU C CA 1 +ATOM 4020 C C . LEU C 1 27 ? -8.760 -29.503 59.124 1.00 124.99 ? 27 LEU C C 1 +ATOM 4021 O O . LEU C 1 27 ? -8.911 -28.812 58.122 1.00 110.62 ? 27 LEU C O 1 +ATOM 4022 C CB . LEU C 1 27 ? -6.345 -30.207 59.160 1.00 138.06 ? 27 LEU C CB 1 +ATOM 4023 C CG . LEU C 1 27 ? -5.355 -31.178 59.815 1.00 156.61 ? 27 LEU C CG 1 +ATOM 4024 C CD1 . LEU C 1 27 ? -3.921 -30.761 59.540 1.00 170.03 ? 27 LEU C CD1 1 +ATOM 4025 C CD2 . LEU C 1 27 ? -5.594 -31.278 61.315 1.00 165.19 ? 27 LEU C CD2 1 +ATOM 4026 N N . PRO C 1 28 ? -9.379 -29.236 60.284 1.00 130.10 ? 28 PRO C N 1 +ATOM 4027 C CA . PRO C 1 28 ? -10.277 -28.083 60.438 1.00 123.18 ? 28 PRO C CA 1 +ATOM 4028 C C . PRO C 1 28 ? -9.596 -26.763 60.120 1.00 113.55 ? 28 PRO C C 1 +ATOM 4029 O O . PRO C 1 28 ? -8.531 -26.485 60.654 1.00 153.61 ? 28 PRO C O 1 +ATOM 4030 C CB . PRO C 1 28 ? -10.656 -28.128 61.924 1.00 150.44 ? 28 PRO C CB 1 +ATOM 4031 C CG . PRO C 1 28 ? -9.532 -28.866 62.591 1.00 153.56 ? 28 PRO C CG 1 +ATOM 4032 C CD . PRO C 1 28 ? -9.072 -29.877 61.579 1.00 148.07 ? 28 PRO C CD 1 +ATOM 4033 N N . ALA C 1 29 ? -10.212 -25.951 59.274 1.00 112.12 ? 29 ALA C N 1 +ATOM 4034 C CA . ALA C 1 29 ? -9.533 -24.780 58.706 1.00 111.01 ? 29 ALA C CA 1 +ATOM 4035 C C . ALA C 1 29 ? -9.363 -23.643 59.737 1.00 107.83 ? 29 ALA C C 1 +ATOM 4036 O O . ALA C 1 29 ? -10.184 -23.484 60.646 1.00 130.39 ? 29 ALA C O 1 +ATOM 4037 C CB . ALA C 1 29 ? -10.273 -24.291 57.457 1.00 98.16 ? 29 ALA C CB 1 +ATOM 4038 N N . PRO C 1 30 ? -8.261 -22.881 59.635 1.00 94.54 ? 30 PRO C N 1 +ATOM 4039 C CA . PRO C 1 30 ? -8.012 -21.696 60.463 1.00 89.54 ? 30 PRO C CA 1 +ATOM 4040 C C . PRO C 1 30 ? -8.852 -20.487 60.031 1.00 86.32 ? 30 PRO C C 1 +ATOM 4041 O O . PRO C 1 30 ? -9.565 -20.558 59.021 1.00 58.03 ? 30 PRO C O 1 +ATOM 4042 C CB . PRO C 1 30 ? -6.554 -21.392 60.198 1.00 93.83 ? 30 PRO C CB 1 +ATOM 4043 C CG . PRO C 1 30 ? -6.333 -21.855 58.799 1.00 116.46 ? 30 PRO C CG 1 +ATOM 4044 C CD . PRO C 1 30 ? -7.242 -23.037 58.588 1.00 111.61 ? 30 PRO C CD 1 +ATOM 4045 N N . THR C 1 31 ? -8.767 -19.396 60.795 1.00 90.19 ? 31 THR C N 1 +ATOM 4046 C CA . THR C 1 31 ? -9.564 -18.194 60.507 1.00 114.11 ? 31 THR C CA 1 +ATOM 4047 C C . THR C 1 31 ? -9.141 -17.517 59.201 1.00 119.17 ? 31 THR C C 1 +ATOM 4048 O O . THR C 1 31 ? -9.933 -16.827 58.561 1.00 91.69 ? 31 THR C O 1 +ATOM 4049 C CB . THR C 1 31 ? -9.521 -17.154 61.661 1.00 134.91 ? 31 THR C CB 1 +ATOM 4050 O OG1 . THR C 1 31 ? -8.168 -16.851 62.024 1.00 129.43 ? 31 THR C OG1 1 +ATOM 4051 C CG2 . THR C 1 31 ? -10.266 -17.667 62.887 1.00 149.22 ? 31 THR C CG2 1 +ATOM 4052 N N . GLY C 1 32 ? -7.874 -17.681 58.840 1.00 140.38 ? 32 GLY C N 1 +ATOM 4053 C CA . GLY C 1 32 ? -7.389 -17.304 57.514 1.00 152.61 ? 32 GLY C CA 1 +ATOM 4054 C C . GLY C 1 32 ? -6.152 -18.125 57.211 1.00 137.51 ? 32 GLY C C 1 +ATOM 4055 O O . GLY C 1 32 ? -5.483 -18.582 58.136 1.00 131.29 ? 32 GLY C O 1 +ATOM 4056 N N . LYS C 1 33 ? -5.851 -18.344 55.932 1.00 114.66 ? 33 LYS C N 1 +ATOM 4057 C CA . LYS C 1 33 ? -4.623 -19.044 55.590 1.00 115.00 ? 33 LYS C CA 1 +ATOM 4058 C C . LYS C 1 33 ? -3.386 -18.198 55.953 1.00 116.95 ? 33 LYS C C 1 +ATOM 4059 O O . LYS C 1 33 ? -3.458 -16.966 55.964 1.00 118.91 ? 33 LYS C O 1 +ATOM 4060 C CB . LYS C 1 33 ? -4.596 -19.423 54.119 1.00 117.13 ? 33 LYS C CB 1 +ATOM 4061 C CG . LYS C 1 33 ? -5.202 -20.778 53.826 1.00 105.32 ? 33 LYS C CG 1 +ATOM 4062 C CD . LYS C 1 33 ? -5.299 -21.004 52.328 1.00 118.63 ? 33 LYS C CD 1 +ATOM 4063 C CE . LYS C 1 33 ? -6.409 -21.987 52.008 1.00 120.80 ? 33 LYS C CE 1 +ATOM 4064 N NZ . LYS C 1 33 ? -6.635 -22.100 50.547 1.00 158.34 ? 33 LYS C NZ 1 +ATOM 4065 N N . ILE C 1 34 ? -2.279 -18.859 56.283 1.00 103.77 ? 34 ILE C N 1 +ATOM 4066 C CA . ILE C 1 34 ? -1.084 -18.165 56.716 1.00 113.46 ? 34 ILE C CA 1 +ATOM 4067 C C . ILE C 1 34 ? -0.065 -18.213 55.566 1.00 139.94 ? 34 ILE C C 1 +ATOM 4068 O O . ILE C 1 34 ? -0.020 -19.176 54.791 1.00 153.36 ? 34 ILE C O 1 +ATOM 4069 C CB . ILE C 1 34 ? -0.552 -18.751 58.053 1.00 128.91 ? 34 ILE C CB 1 +ATOM 4070 C CG1 . ILE C 1 34 ? -1.540 -18.470 59.182 1.00 147.72 ? 34 ILE C CG1 1 +ATOM 4071 C CG2 . ILE C 1 34 ? 0.785 -18.143 58.459 1.00 148.00 ? 34 ILE C CG2 1 +ATOM 4072 C CD1 . ILE C 1 34 ? -2.110 -19.722 59.810 1.00 171.96 ? 34 ILE C CD1 1 +ATOM 4073 N N . PHE C 1 35 ? 0.663 -17.109 55.397 1.00 142.95 ? 35 PHE C N 1 +ATOM 4074 C CA . PHE C 1 35 ? 1.673 -16.963 54.354 1.00 110.45 ? 35 PHE C CA 1 +ATOM 4075 C C . PHE C 1 35 ? 2.975 -17.591 54.814 1.00 111.60 ? 35 PHE C C 1 +ATOM 4076 O O . PHE C 1 35 ? 3.529 -17.173 55.829 1.00 129.12 ? 35 PHE C O 1 +ATOM 4077 C CB . PHE C 1 35 ? 1.929 -15.477 54.100 1.00 104.89 ? 35 PHE C CB 1 +ATOM 4078 C CG . PHE C 1 35 ? 0.987 -14.850 53.127 1.00 91.04 ? 35 PHE C CG 1 +ATOM 4079 C CD1 . PHE C 1 35 ? 0.636 -15.504 51.947 1.00 75.54 ? 35 PHE C CD1 1 +ATOM 4080 C CD2 . PHE C 1 35 ? 0.527 -13.561 53.349 1.00 85.26 ? 35 PHE C CD2 1 +ATOM 4081 C CE1 . PHE C 1 35 ? -0.214 -14.901 51.042 1.00 91.65 ? 35 PHE C CE1 1 +ATOM 4082 C CE2 . PHE C 1 35 ? -0.324 -12.956 52.443 1.00 100.40 ? 35 PHE C CE2 1 +ATOM 4083 C CZ . PHE C 1 35 ? -0.702 -13.627 51.290 1.00 94.72 ? 35 PHE C CZ 1 +ATOM 4084 N N . VAL C 1 36 ? 3.519 -18.512 54.021 1.00 110.22 ? 36 VAL C N 1 +ATOM 4085 C CA . VAL C 1 36 ? 4.733 -19.206 54.427 1.00 89.31 ? 36 VAL C CA 1 +ATOM 4086 C C . VAL C 1 36 ? 5.800 -19.251 53.342 1.00 100.93 ? 36 VAL C C 1 +ATOM 4087 O O . VAL C 1 36 ? 5.507 -19.218 52.152 1.00 137.25 ? 36 VAL C O 1 +ATOM 4088 C CB . VAL C 1 36 ? 4.400 -20.626 54.842 1.00 85.34 ? 36 VAL C CB 1 +ATOM 4089 C CG1 . VAL C 1 36 ? 4.121 -21.505 53.625 1.00 87.34 ? 36 VAL C CG1 1 +ATOM 4090 C CG2 . VAL C 1 36 ? 5.528 -21.185 55.668 1.00 91.41 ? 36 VAL C CG2 1 +ATOM 4091 N N . SER C 1 37 ? 7.050 -19.294 53.766 1.00 95.81 ? 37 SER C N 1 +ATOM 4092 C CA . SER C 1 37 ? 8.168 -19.346 52.837 1.00 99.61 ? 37 SER C CA 1 +ATOM 4093 C C . SER C 1 37 ? 8.972 -20.604 53.130 1.00 90.40 ? 37 SER C C 1 +ATOM 4094 O O . SER C 1 37 ? 9.343 -20.850 54.257 1.00 55.58 ? 37 SER C O 1 +ATOM 4095 C CB . SER C 1 37 ? 9.074 -18.129 53.026 1.00 86.44 ? 37 SER C CB 1 +ATOM 4096 O OG . SER C 1 37 ? 8.508 -16.959 52.501 1.00 56.36 ? 37 SER C OG 1 +ATOM 4097 N N . VAL C 1 38 ? 9.316 -21.355 52.096 1.00 101.76 ? 38 VAL C N 1 +ATOM 4098 C CA . VAL C 1 38 ? 10.336 -22.392 52.246 1.00 99.51 ? 38 VAL C CA 1 +ATOM 4099 C C . VAL C 1 38 ? 11.485 -22.151 51.269 1.00 93.02 ? 38 VAL C C 1 +ATOM 4100 O O . VAL C 1 38 ? 11.265 -22.150 50.054 1.00 116.35 ? 38 VAL C O 1 +ATOM 4101 C CB . VAL C 1 38 ? 9.776 -23.796 51.961 1.00 92.53 ? 38 VAL C CB 1 +ATOM 4102 C CG1 . VAL C 1 38 ? 10.881 -24.828 52.089 1.00 87.32 ? 38 VAL C CG1 1 +ATOM 4103 C CG2 . VAL C 1 38 ? 8.622 -24.126 52.894 1.00 89.61 ? 38 VAL C CG2 1 +ATOM 4104 N N . TYR C 1 39 ? 12.686 -21.965 51.808 1.00 67.45 ? 39 TYR C N 1 +ATOM 4105 C CA . TYR C 1 39 ? 13.854 -21.679 51.011 1.00 69.91 ? 39 TYR C CA 1 +ATOM 4106 C C . TYR C 1 39 ? 14.534 -22.997 50.647 1.00 88.70 ? 39 TYR C C 1 +ATOM 4107 O O . TYR C 1 39 ? 14.806 -23.265 49.474 1.00 129.86 ? 39 TYR C O 1 +ATOM 4108 C CB . TYR C 1 39 ? 14.803 -20.715 51.757 1.00 72.22 ? 39 TYR C CB 1 +ATOM 4109 C CG . TYR C 1 39 ? 14.440 -19.250 51.550 1.00 73.03 ? 39 TYR C CG 1 +ATOM 4110 C CD1 . TYR C 1 39 ? 13.373 -18.665 52.214 1.00 56.32 ? 39 TYR C CD1 1 +ATOM 4111 C CD2 . TYR C 1 39 ? 15.171 -18.455 50.669 1.00 100.41 ? 39 TYR C CD2 1 +ATOM 4112 C CE1 . TYR C 1 39 ? 13.067 -17.338 52.033 1.00 61.37 ? 39 TYR C CE1 1 +ATOM 4113 C CE2 . TYR C 1 39 ? 14.859 -17.117 50.464 1.00 109.26 ? 39 TYR C CE2 1 +ATOM 4114 C CZ . TYR C 1 39 ? 13.788 -16.564 51.132 1.00 84.34 ? 39 TYR C CZ 1 +ATOM 4115 O OH . TYR C 1 39 ? 13.472 -15.219 50.888 1.00 86.61 ? 39 TYR C OH 1 +ATOM 4116 N N . ASN C 1 40 ? 14.842 -23.821 51.643 1.00 102.53 ? 40 ASN C N 1 +ATOM 4117 C CA . ASN C 1 40 ? 15.542 -25.087 51.386 1.00 97.63 ? 40 ASN C CA 1 +ATOM 4118 C C . ASN C 1 40 ? 15.571 -26.066 52.557 1.00 87.86 ? 40 ASN C C 1 +ATOM 4119 O O . ASN C 1 40 ? 15.839 -25.682 53.698 1.00 90.65 ? 40 ASN C O 1 +ATOM 4120 C CB . ASN C 1 40 ? 16.982 -24.821 50.991 1.00 98.87 ? 40 ASN C CB 1 +ATOM 4121 C CG . ASN C 1 40 ? 17.604 -26.004 50.292 1.00 120.45 ? 40 ASN C CG 1 +ATOM 4122 O OD1 . ASN C 1 40 ? 18.563 -26.590 50.782 1.00 143.92 ? 40 ASN C OD1 1 +ATOM 4123 N ND2 . ASN C 1 40 ? 17.061 -26.355 49.126 1.00 128.63 ? 40 ASN C ND2 1 +ATOM 4124 N N . ILE C 1 41 ? 15.240 -27.323 52.280 1.00 92.04 ? 41 ILE C N 1 +ATOM 4125 C CA . ILE C 1 41 ? 15.401 -28.391 53.259 1.00 97.54 ? 41 ILE C CA 1 +ATOM 4126 C C . ILE C 1 41 ? 16.431 -29.378 52.713 1.00 120.18 ? 41 ILE C C 1 +ATOM 4127 O O . ILE C 1 41 ? 16.188 -30.024 51.687 1.00 119.16 ? 41 ILE C O 1 +ATOM 4128 C CB . ILE C 1 41 ? 14.070 -29.120 53.570 1.00 79.06 ? 41 ILE C CB 1 +ATOM 4129 C CG1 . ILE C 1 41 ? 13.229 -28.341 54.579 1.00 90.05 ? 41 ILE C CG1 1 +ATOM 4130 C CG2 . ILE C 1 41 ? 14.348 -30.465 54.215 1.00 80.00 ? 41 ILE C CG2 1 +ATOM 4131 C CD1 . ILE C 1 41 ? 12.612 -27.063 54.054 1.00 105.20 ? 41 ILE C CD1 1 +ATOM 4132 N N . GLN C 1 42 ? 17.561 -29.513 53.410 1.00 113.01 ? 42 GLN C N 1 +ATOM 4133 C CA . GLN C 1 42 ? 18.696 -30.268 52.875 1.00 110.04 ? 42 GLN C CA 1 +ATOM 4134 C C . GLN C 1 42 ? 18.644 -31.762 53.198 1.00 71.74 ? 42 GLN C C 1 +ATOM 4135 O O . GLN C 1 42 ? 18.071 -32.146 54.196 1.00 51.31 ? 42 GLN C O 1 +ATOM 4136 C CB . GLN C 1 42 ? 20.019 -29.658 53.366 1.00 133.40 ? 42 GLN C CB 1 +ATOM 4137 C CG . GLN C 1 42 ? 20.281 -28.281 52.698 1.00 151.73 ? 42 GLN C CG 1 +ATOM 4138 C CD . GLN C 1 42 ? 20.845 -28.405 51.291 1.00 181.31 ? 42 GLN C CD 1 +ATOM 4139 O OE1 . GLN C 1 42 ? 21.284 -29.472 50.775 1.00 210.47 ? 42 GLN C OE1 1 +ATOM 4140 N NE2 . GLN C 1 42 ? 20.753 -27.291 50.630 1.00 202.56 ? 42 GLN C NE2 1 +ATOM 4141 N N . ASP C 1 43 ? 19.297 -32.562 52.357 1.00 53.32 ? 43 ASP C N 1 +ATOM 4142 C CA . ASP C 1 43 ? 19.626 -33.919 52.670 1.00 50.59 ? 43 ASP C CA 1 +ATOM 4143 C C . ASP C 1 43 ? 20.805 -33.982 53.623 1.00 58.73 ? 43 ASP C C 1 +ATOM 4144 O O . ASP C 1 43 ? 21.866 -34.538 53.285 1.00 57.63 ? 43 ASP C O 1 +ATOM 4145 C CB . ASP C 1 43 ? 19.974 -34.681 51.408 1.00 58.51 ? 43 ASP C CB 1 +ATOM 4146 C CG . ASP C 1 43 ? 20.072 -36.205 51.643 1.00 83.46 ? 43 ASP C CG 1 +ATOM 4147 O OD1 . ASP C 1 43 ? 19.118 -36.779 52.217 1.00 116.64 ? 43 ASP C OD1 1 +ATOM 4148 O OD2 . ASP C 1 43 ? 21.030 -36.860 51.163 1.00 97.71 ? 43 ASP C OD2 1 +ATOM 4149 N N . GLU C 1 44 ? 20.612 -33.480 54.853 1.00 78.37 ? 44 GLU C N 1 +ATOM 4150 C CA . GLU C 1 44 ? 21.659 -33.506 55.903 1.00 109.79 ? 44 GLU C CA 1 +ATOM 4151 C C . GLU C 1 44 ? 21.992 -34.953 56.446 1.00 94.46 ? 44 GLU C C 1 +ATOM 4152 O O . GLU C 1 44 ? 22.733 -35.102 57.450 1.00 45.48 ? 44 GLU C O 1 +ATOM 4153 C CB . GLU C 1 44 ? 21.285 -32.575 57.085 1.00 121.19 ? 44 GLU C CB 1 +ATOM 4154 C CG . GLU C 1 44 ? 21.672 -31.094 56.920 1.00 123.26 ? 44 GLU C CG 1 +ATOM 4155 C CD . GLU C 1 44 ? 21.272 -30.176 58.104 1.00 118.30 ? 44 GLU C CD 1 +ATOM 4156 O OE1 . GLU C 1 44 ? 21.407 -30.554 59.290 1.00 142.75 ? 44 GLU C OE1 1 +ATOM 4157 O OE2 . GLU C 1 44 ? 20.725 -29.091 57.860 1.00 86.06 ? 44 GLU C OE2 1 +ATOM 4158 N N . THR C 1 45 ? 21.571 -35.973 55.682 1.00 85.91 ? 45 THR C N 1 +ATOM 4159 C CA . THR C 1 45 ? 21.667 -37.364 56.103 1.00 85.27 ? 45 THR C CA 1 +ATOM 4160 C C . THR C 1 45 ? 23.063 -37.961 56.017 1.00 89.43 ? 45 THR C C 1 +ATOM 4161 O O . THR C 1 45 ? 23.500 -38.646 56.928 1.00 83.37 ? 45 THR C O 1 +ATOM 4162 C CB . THR C 1 45 ? 20.658 -38.265 55.360 1.00 71.73 ? 45 THR C CB 1 +ATOM 4163 O OG1 . THR C 1 45 ? 20.567 -39.507 56.058 1.00 148.28 ? 45 THR C OG1 1 +ATOM 4164 C CG2 . THR C 1 45 ? 21.040 -38.531 53.928 1.00 51.79 ? 45 THR C CG2 1 +ATOM 4165 N N . GLY C 1 46 ? 23.787 -37.645 54.952 1.00 123.18 ? 46 GLY C N 1 +ATOM 4166 C CA . GLY C 1 46 ? 25.214 -38.002 54.857 1.00 114.20 ? 46 GLY C CA 1 +ATOM 4167 C C . GLY C 1 46 ? 25.388 -39.393 54.270 1.00 115.78 ? 46 GLY C C 1 +ATOM 4168 O O . GLY C 1 46 ? 26.457 -40.030 54.355 1.00 135.50 ? 46 GLY C O 1 +ATOM 4169 N N . GLN C 1 47 ? 24.380 -39.845 53.560 1.00 84.03 ? 47 GLN C N 1 +ATOM 4170 C CA . GLN C 1 47 ? 24.357 -41.209 53.280 1.00 66.13 ? 47 GLN C CA 1 +ATOM 4171 C C . GLN C 1 47 ? 24.124 -41.468 51.808 1.00 68.53 ? 47 GLN C C 1 +ATOM 4172 O O . GLN C 1 47 ? 23.288 -40.842 51.130 1.00 82.85 ? 47 GLN C O 1 +ATOM 4173 C CB . GLN C 1 47 ? 23.317 -41.822 54.152 1.00 64.18 ? 47 GLN C CB 1 +ATOM 4174 C CG . GLN C 1 47 ? 23.704 -41.807 55.602 1.00 72.01 ? 47 GLN C CG 1 +ATOM 4175 C CD . GLN C 1 47 ? 25.093 -42.369 55.826 1.00 114.53 ? 47 GLN C CD 1 +ATOM 4176 O OE1 . GLN C 1 47 ? 25.321 -43.574 55.749 1.00 130.59 ? 47 GLN C OE1 1 +ATOM 4177 N NE2 . GLN C 1 47 ? 26.023 -41.503 56.171 1.00 171.77 ? 47 GLN C NE2 1 +ATOM 4178 N N . PHE C 1 48 ? 24.847 -42.466 51.327 1.00 70.01 ? 48 PHE C N 1 +ATOM 4179 C CA . PHE C 1 48 ? 24.706 -42.959 49.969 1.00 75.01 ? 48 PHE C CA 1 +ATOM 4180 C C . PHE C 1 48 ? 24.365 -44.459 49.963 1.00 84.64 ? 48 PHE C C 1 +ATOM 4181 O O . PHE C 1 48 ? 24.561 -45.185 50.946 1.00 100.79 ? 48 PHE C O 1 +ATOM 4182 C CB . PHE C 1 48 ? 26.005 -42.693 49.189 1.00 65.72 ? 48 PHE C CB 1 +ATOM 4183 C CG . PHE C 1 48 ? 26.268 -41.265 48.997 1.00 52.06 ? 48 PHE C CG 1 +ATOM 4184 C CD1 . PHE C 1 48 ? 26.640 -40.497 50.064 1.00 54.24 ? 48 PHE C CD1 1 +ATOM 4185 C CD2 . PHE C 1 48 ? 26.022 -40.680 47.801 1.00 58.28 ? 48 PHE C CD2 1 +ATOM 4186 C CE1 . PHE C 1 48 ? 26.788 -39.143 49.955 1.00 67.24 ? 48 PHE C CE1 1 +ATOM 4187 C CE2 . PHE C 1 48 ? 26.152 -39.327 47.672 1.00 86.68 ? 48 PHE C CE2 1 +ATOM 4188 C CZ . PHE C 1 48 ? 26.560 -38.556 48.748 1.00 92.09 ? 48 PHE C CZ 1 +ATOM 4189 N N . LYS C 1 49 ? 23.978 -44.933 48.791 1.00 95.49 ? 49 LYS C N 1 +ATOM 4190 C CA . LYS C 1 49 ? 23.657 -46.334 48.618 1.00 93.32 ? 49 LYS C CA 1 +ATOM 4191 C C . LYS C 1 49 ? 24.927 -47.177 48.564 1.00 83.39 ? 49 LYS C C 1 +ATOM 4192 O O . LYS C 1 49 ? 25.962 -46.746 48.034 1.00 86.67 ? 49 LYS C O 1 +ATOM 4193 C CB . LYS C 1 49 ? 22.795 -46.526 47.357 1.00 114.06 ? 49 LYS C CB 1 +ATOM 4194 C CG . LYS C 1 49 ? 21.443 -45.833 47.488 1.00 111.89 ? 49 LYS C CG 1 +ATOM 4195 C CD . LYS C 1 49 ? 20.425 -46.124 46.403 1.00 133.44 ? 49 LYS C CD 1 +ATOM 4196 C CE . LYS C 1 49 ? 19.110 -45.476 46.842 1.00 165.60 ? 49 LYS C CE 1 +ATOM 4197 N NZ . LYS C 1 49 ? 17.953 -45.683 45.927 1.00 197.21 ? 49 LYS C NZ 1 +ATOM 4198 N N . PRO C 1 50 ? 24.832 -48.402 49.079 1.00 82.79 ? 50 PRO C N 1 +ATOM 4199 C CA . PRO C 1 50 ? 25.940 -49.334 49.046 1.00 97.47 ? 50 PRO C CA 1 +ATOM 4200 C C . PRO C 1 50 ? 26.120 -50.023 47.686 1.00 75.68 ? 50 PRO C C 1 +ATOM 4201 O O . PRO C 1 50 ? 25.237 -49.974 46.835 1.00 63.11 ? 50 PRO C O 1 +ATOM 4202 C CB . PRO C 1 50 ? 25.564 -50.358 50.131 1.00 106.76 ? 50 PRO C CB 1 +ATOM 4203 C CG . PRO C 1 50 ? 24.081 -50.353 50.143 1.00 94.53 ? 50 PRO C CG 1 +ATOM 4204 C CD . PRO C 1 50 ? 23.672 -48.945 49.806 1.00 89.49 ? 50 PRO C CD 1 +ATOM 4205 N N . TYR C 1 51 ? 27.272 -50.666 47.517 1.00 75.76 ? 51 TYR C N 1 +ATOM 4206 C CA . TYR C 1 51 ? 27.488 -51.527 46.386 1.00 71.60 ? 51 TYR C CA 1 +ATOM 4207 C C . TYR C 1 51 ? 26.296 -52.469 46.232 1.00 74.32 ? 51 TYR C C 1 +ATOM 4208 O O . TYR C 1 51 ? 25.820 -53.040 47.216 1.00 66.31 ? 51 TYR C O 1 +ATOM 4209 C CB . TYR C 1 51 ? 28.781 -52.336 46.546 1.00 73.26 ? 51 TYR C CB 1 +ATOM 4210 C CG . TYR C 1 51 ? 29.214 -52.948 45.249 1.00 75.23 ? 51 TYR C CG 1 +ATOM 4211 C CD1 . TYR C 1 51 ? 30.007 -52.237 44.383 1.00 91.68 ? 51 TYR C CD1 1 +ATOM 4212 C CD2 . TYR C 1 51 ? 28.819 -54.233 44.871 1.00 86.84 ? 51 TYR C CD2 1 +ATOM 4213 C CE1 . TYR C 1 51 ? 30.385 -52.749 43.151 1.00 101.92 ? 51 TYR C CE1 1 +ATOM 4214 C CE2 . TYR C 1 51 ? 29.240 -54.784 43.654 1.00 100.06 ? 51 TYR C CE2 1 +ATOM 4215 C CZ . TYR C 1 51 ? 29.989 -54.000 42.782 1.00 102.63 ? 51 TYR C CZ 1 +ATOM 4216 O OH . TYR C 1 51 ? 30.388 -54.440 41.546 1.00 95.68 ? 51 TYR C OH 1 +ATOM 4217 N N . PRO C 1 52 ? 25.813 -52.657 44.993 1.00 88.14 ? 52 PRO C N 1 +ATOM 4218 C CA . PRO C 1 52 ? 26.340 -52.189 43.703 1.00 110.50 ? 52 PRO C CA 1 +ATOM 4219 C C . PRO C 1 52 ? 25.807 -50.860 43.160 1.00 128.52 ? 52 PRO C C 1 +ATOM 4220 O O . PRO C 1 52 ? 25.970 -50.600 41.963 1.00 93.99 ? 52 PRO C O 1 +ATOM 4221 C CB . PRO C 1 52 ? 25.909 -53.300 42.747 1.00 114.43 ? 52 PRO C CB 1 +ATOM 4222 C CG . PRO C 1 52 ? 24.591 -53.738 43.299 1.00 114.14 ? 52 PRO C CG 1 +ATOM 4223 C CD . PRO C 1 52 ? 24.693 -53.597 44.802 1.00 99.47 ? 52 PRO C CD 1 +ATOM 4224 N N . ALA C 1 53 ? 25.213 -50.020 44.011 1.00 140.61 ? 53 ALA C N 1 +ATOM 4225 C CA . ALA C 1 53 ? 24.785 -48.700 43.557 1.00 128.27 ? 53 ALA C CA 1 +ATOM 4226 C C . ALA C 1 53 ? 25.989 -47.877 43.128 1.00 130.93 ? 53 ALA C C 1 +ATOM 4227 O O . ALA C 1 53 ? 27.148 -48.137 43.524 1.00 88.41 ? 53 ALA C O 1 +ATOM 4228 C CB . ALA C 1 53 ? 24.016 -47.962 44.638 1.00 136.50 ? 53 ALA C CB 1 +ATOM 4229 N N . SER C 1 54 ? 25.726 -46.855 42.325 1.00 120.38 ? 54 SER C N 1 +ATOM 4230 C CA . SER C 1 54 ? 26.779 -45.897 42.074 1.00 104.71 ? 54 SER C CA 1 +ATOM 4231 C C . SER C 1 54 ? 27.239 -45.337 43.422 1.00 81.27 ? 54 SER C C 1 +ATOM 4232 O O . SER C 1 54 ? 26.415 -45.031 44.304 1.00 68.42 ? 54 SER C O 1 +ATOM 4233 C CB . SER C 1 54 ? 26.316 -44.793 41.111 1.00 113.18 ? 54 SER C CB 1 +ATOM 4234 O OG . SER C 1 54 ? 27.115 -43.609 41.215 1.00 87.88 ? 54 SER C OG 1 +ATOM 4235 N N . ASN C 1 55 ? 28.546 -45.132 43.525 1.00 62.01 ? 55 ASN C N 1 +ATOM 4236 C CA . ASN C 1 55 ? 29.126 -44.377 44.610 1.00 60.46 ? 55 ASN C CA 1 +ATOM 4237 C C . ASN C 1 55 ? 28.367 -43.071 44.970 1.00 74.56 ? 55 ASN C C 1 +ATOM 4238 O O . ASN C 1 55 ? 28.279 -42.640 46.130 1.00 47.29 ? 55 ASN C O 1 +ATOM 4239 C CB . ASN C 1 55 ? 30.548 -44.020 44.246 1.00 48.59 ? 55 ASN C CB 1 +ATOM 4240 C CG . ASN C 1 55 ? 31.356 -43.658 45.439 1.00 74.95 ? 55 ASN C CG 1 +ATOM 4241 O OD1 . ASN C 1 55 ? 31.007 -43.956 46.591 1.00 150.18 ? 55 ASN C OD1 1 +ATOM 4242 N ND2 . ASN C 1 55 ? 32.491 -43.074 45.185 1.00 91.34 ? 55 ASN C ND2 1 +ATOM 4243 N N . PHE C 1 56 ? 27.758 -42.469 43.951 1.00 102.89 ? 56 PHE C N 1 +ATOM 4244 C CA . PHE C 1 56 ? 27.144 -41.142 44.060 1.00 95.79 ? 56 PHE C CA 1 +ATOM 4245 C C . PHE C 1 56 ? 25.629 -41.173 44.248 1.00 98.91 ? 56 PHE C C 1 +ATOM 4246 O O . PHE C 1 56 ? 24.986 -40.124 44.296 1.00 93.77 ? 56 PHE C O 1 +ATOM 4247 C CB . PHE C 1 56 ? 27.416 -40.344 42.797 1.00 88.19 ? 56 PHE C CB 1 +ATOM 4248 C CG . PHE C 1 56 ? 28.886 -40.196 42.490 1.00 76.16 ? 56 PHE C CG 1 +ATOM 4249 C CD1 . PHE C 1 56 ? 29.762 -39.580 43.366 1.00 46.33 ? 56 PHE C CD1 1 +ATOM 4250 C CD2 . PHE C 1 56 ? 29.382 -40.713 41.325 1.00 98.83 ? 56 PHE C CD2 1 +ATOM 4251 C CE1 . PHE C 1 56 ? 31.086 -39.434 43.053 1.00 39.32 ? 56 PHE C CE1 1 +ATOM 4252 C CE2 . PHE C 1 56 ? 30.718 -40.530 40.992 1.00 82.49 ? 56 PHE C CE2 1 +ATOM 4253 C CZ . PHE C 1 56 ? 31.572 -39.897 41.867 1.00 45.33 ? 56 PHE C CZ 1 +ATOM 4254 N N . SER C 1 57 ? 25.042 -42.362 44.295 1.00 81.14 ? 57 SER C N 1 +ATOM 4255 C CA . SER C 1 57 ? 23.600 -42.457 44.491 1.00 64.10 ? 57 SER C CA 1 +ATOM 4256 C C . SER C 1 57 ? 23.253 -42.171 45.944 1.00 58.19 ? 57 SER C C 1 +ATOM 4257 O O . SER C 1 57 ? 23.673 -42.901 46.865 1.00 57.90 ? 57 SER C O 1 +ATOM 4258 C CB . SER C 1 57 ? 23.086 -43.831 44.065 1.00 62.90 ? 57 SER C CB 1 +ATOM 4259 O OG . SER C 1 57 ? 23.073 -43.919 42.651 1.00 64.79 ? 57 SER C OG 1 +ATOM 4260 N N . THR C 1 58 ? 22.537 -41.079 46.172 1.00 51.37 ? 58 THR C N 1 +ATOM 4261 C CA . THR C 1 58 ? 22.189 -40.714 47.533 1.00 67.74 ? 58 THR C CA 1 +ATOM 4262 C C . THR C 1 58 ? 21.168 -41.683 48.106 1.00 75.04 ? 58 THR C C 1 +ATOM 4263 O O . THR C 1 58 ? 20.336 -42.213 47.414 1.00 79.46 ? 58 THR C O 1 +ATOM 4264 C CB . THR C 1 58 ? 21.595 -39.305 47.598 1.00 54.68 ? 58 THR C CB 1 +ATOM 4265 O OG1 . THR C 1 58 ? 20.398 -39.266 46.834 1.00 47.33 ? 58 THR C OG1 1 +ATOM 4266 C CG2 . THR C 1 58 ? 22.566 -38.343 47.036 1.00 45.14 ? 58 THR C CG2 1 +ATOM 4267 N N . ALA C 1 59 ? 21.161 -41.841 49.408 1.00 83.51 ? 59 ALA C N 1 +ATOM 4268 C CA . ALA C 1 59 ? 20.220 -42.765 49.977 1.00 82.28 ? 59 ALA C CA 1 +ATOM 4269 C C . ALA C 1 59 ? 18.823 -42.175 50.026 1.00 79.12 ? 59 ALA C C 1 +ATOM 4270 O O . ALA C 1 59 ? 17.834 -42.904 50.131 1.00 124.31 ? 59 ALA C O 1 +ATOM 4271 C CB . ALA C 1 59 ? 20.667 -43.171 51.360 1.00 106.65 ? 59 ALA C CB 1 +ATOM 4272 N N . VAL C 1 60 ? 18.740 -40.851 49.973 1.00 83.70 ? 60 VAL C N 1 +ATOM 4273 C CA . VAL C 1 60 ? 17.483 -40.140 50.160 1.00 100.33 ? 60 VAL C CA 1 +ATOM 4274 C C . VAL C 1 60 ? 17.326 -39.131 49.031 1.00 100.22 ? 60 VAL C C 1 +ATOM 4275 O O . VAL C 1 60 ? 18.296 -38.472 48.642 1.00 102.05 ? 60 VAL C O 1 +ATOM 4276 C CB . VAL C 1 60 ? 17.499 -39.397 51.508 1.00 101.64 ? 60 VAL C CB 1 +ATOM 4277 C CG1 . VAL C 1 60 ? 16.210 -38.604 51.733 1.00 106.24 ? 60 VAL C CG1 1 +ATOM 4278 C CG2 . VAL C 1 60 ? 17.731 -40.381 52.640 1.00 100.59 ? 60 VAL C CG2 1 +ATOM 4279 N N . PRO C 1 61 ? 16.105 -38.990 48.511 1.00 75.25 ? 61 PRO C N 1 +ATOM 4280 C CA . PRO C 1 61 ? 15.928 -38.000 47.461 1.00 91.59 ? 61 PRO C CA 1 +ATOM 4281 C C . PRO C 1 61 ? 16.182 -36.570 47.918 1.00 97.65 ? 61 PRO C C 1 +ATOM 4282 O O . PRO C 1 61 ? 15.837 -36.206 49.052 1.00 73.37 ? 61 PRO C O 1 +ATOM 4283 C CB . PRO C 1 61 ? 14.465 -38.175 47.051 1.00 92.21 ? 61 PRO C CB 1 +ATOM 4284 C CG . PRO C 1 61 ? 13.820 -38.825 48.225 1.00 72.12 ? 61 PRO C CG 1 +ATOM 4285 C CD . PRO C 1 61 ? 14.869 -39.713 48.806 1.00 59.50 ? 61 PRO C CD 1 +ATOM 4286 N N . GLN C 1 62 ? 16.736 -35.764 47.008 1.00 114.59 ? 62 GLN C N 1 +ATOM 4287 C CA . GLN C 1 62 ? 17.125 -34.390 47.316 1.00 114.02 ? 62 GLN C CA 1 +ATOM 4288 C C . GLN C 1 62 ? 15.955 -33.442 47.086 1.00 117.42 ? 62 GLN C C 1 +ATOM 4289 O O . GLN C 1 62 ? 16.163 -32.294 46.711 1.00 156.28 ? 62 GLN C O 1 +ATOM 4290 C CB . GLN C 1 62 ? 18.301 -33.946 46.433 1.00 94.25 ? 62 GLN C CB 1 +ATOM 4291 C CG . GLN C 1 62 ? 19.450 -34.923 46.392 1.00 79.59 ? 62 GLN C CG 1 +ATOM 4292 C CD . GLN C 1 62 ? 20.014 -35.177 47.764 1.00 85.61 ? 62 GLN C CD 1 +ATOM 4293 O OE1 . GLN C 1 62 ? 20.747 -34.348 48.316 1.00 118.23 ? 62 GLN C OE1 1 +ATOM 4294 N NE2 . GLN C 1 62 ? 19.662 -36.310 48.344 1.00 76.06 ? 62 GLN C NE2 1 +ATOM 4295 N N . SER C 1 63 ? 14.743 -33.903 47.371 1.00 82.96 ? 63 SER C N 1 +ATOM 4296 C CA . SER C 1 63 ? 13.556 -33.228 46.909 1.00 74.28 ? 63 SER C CA 1 +ATOM 4297 C C . SER C 1 63 ? 12.642 -32.769 48.051 1.00 75.55 ? 63 SER C C 1 +ATOM 4298 O O . SER C 1 63 ? 11.503 -32.341 47.838 1.00 80.23 ? 63 SER C O 1 +ATOM 4299 C CB . SER C 1 63 ? 12.820 -34.170 45.955 1.00 81.67 ? 63 SER C CB 1 +ATOM 4300 O OG . SER C 1 63 ? 12.379 -35.366 46.582 1.00 97.22 ? 63 SER C OG 1 +ATOM 4301 N N . ALA C 1 64 ? 13.140 -32.882 49.273 1.00 84.57 ? 64 ALA C N 1 +ATOM 4302 C CA . ALA C 1 64 ? 12.344 -32.625 50.472 1.00 88.81 ? 64 ALA C CA 1 +ATOM 4303 C C . ALA C 1 64 ? 11.652 -31.241 50.463 1.00 102.52 ? 64 ALA C C 1 +ATOM 4304 O O . ALA C 1 64 ? 10.514 -31.086 50.923 1.00 70.13 ? 64 ALA C O 1 +ATOM 4305 C CB . ALA C 1 64 ? 13.231 -32.773 51.696 1.00 91.48 ? 64 ALA C CB 1 +ATOM 4306 N N . THR C 1 65 ? 12.370 -30.243 49.959 1.00 121.80 ? 65 THR C N 1 +ATOM 4307 C CA . THR C 1 65 ? 11.894 -28.870 49.928 1.00 119.22 ? 65 THR C CA 1 +ATOM 4308 C C . THR C 1 65 ? 10.541 -28.794 49.257 1.00 122.72 ? 65 THR C C 1 +ATOM 4309 O O . THR C 1 65 ? 9.609 -28.165 49.774 1.00 204.93 ? 65 THR C O 1 +ATOM 4310 C CB . THR C 1 65 ? 12.864 -28.006 49.124 1.00 118.73 ? 65 THR C CB 1 +ATOM 4311 O OG1 . THR C 1 65 ? 14.201 -28.403 49.447 1.00 150.41 ? 65 THR C OG1 1 +ATOM 4312 C CG2 . THR C 1 65 ? 12.654 -26.525 49.432 1.00 108.45 ? 65 THR C CG2 1 +ATOM 4313 N N . ALA C 1 66 ? 10.433 -29.420 48.096 1.00 92.60 ? 66 ALA C N 1 +ATOM 4314 C CA . ALA C 1 66 ? 9.225 -29.303 47.316 1.00 103.47 ? 66 ALA C CA 1 +ATOM 4315 C C . ALA C 1 66 ? 8.100 -30.079 47.978 1.00 86.49 ? 66 ALA C C 1 +ATOM 4316 O O . ALA C 1 66 ? 6.922 -29.674 47.904 1.00 62.40 ? 66 ALA C O 1 +ATOM 4317 C CB . ALA C 1 66 ? 9.479 -29.786 45.897 1.00 141.43 ? 66 ALA C CB 1 +ATOM 4318 N N . MET C 1 67 ? 8.472 -31.194 48.620 1.00 82.71 ? 67 MET C N 1 +ATOM 4319 C CA . MET C 1 67 ? 7.494 -32.032 49.331 1.00 95.34 ? 67 MET C CA 1 +ATOM 4320 C C . MET C 1 67 ? 6.893 -31.252 50.502 1.00 106.17 ? 67 MET C C 1 +ATOM 4321 O O . MET C 1 67 ? 5.663 -31.261 50.725 1.00 85.25 ? 67 MET C O 1 +ATOM 4322 C CB . MET C 1 67 ? 8.128 -33.312 49.861 1.00 70.81 ? 67 MET C CB 1 +ATOM 4323 C CG . MET C 1 67 ? 8.506 -34.339 48.804 1.00 62.81 ? 67 MET C CG 1 +ATOM 4324 S SD . MET C 1 67 ? 9.552 -35.633 49.537 1.00 98.39 ? 67 MET C SD 1 +ATOM 4325 C CE . MET C 1 67 ? 9.692 -36.787 48.171 1.00 77.59 ? 67 MET C CE 1 +ATOM 4326 N N . LEU C 1 68 ? 7.750 -30.509 51.199 1.00 103.16 ? 68 LEU C N 1 +ATOM 4327 C CA . LEU C 1 68 ? 7.277 -29.670 52.300 1.00 101.47 ? 68 LEU C CA 1 +ATOM 4328 C C . LEU C 1 68 ? 6.334 -28.566 51.814 1.00 82.30 ? 68 LEU C C 1 +ATOM 4329 O O . LEU C 1 68 ? 5.300 -28.338 52.430 1.00 71.43 ? 68 LEU C O 1 +ATOM 4330 C CB . LEU C 1 68 ? 8.438 -29.037 53.071 1.00 85.26 ? 68 LEU C CB 1 +ATOM 4331 C CG . LEU C 1 68 ? 7.964 -27.994 54.098 1.00 76.34 ? 68 LEU C CG 1 +ATOM 4332 C CD1 . LEU C 1 68 ? 7.180 -28.647 55.219 1.00 84.95 ? 68 LEU C CD1 1 +ATOM 4333 C CD2 . LEU C 1 68 ? 9.130 -27.216 54.672 1.00 82.45 ? 68 LEU C CD2 1 +ATOM 4334 N N . VAL C 1 69 ? 6.702 -27.895 50.721 1.00 70.94 ? 69 VAL C N 1 +ATOM 4335 C CA . VAL C 1 69 ? 5.892 -26.820 50.192 1.00 77.90 ? 69 VAL C CA 1 +ATOM 4336 C C . VAL C 1 69 ? 4.530 -27.376 49.782 1.00 104.95 ? 69 VAL C C 1 +ATOM 4337 O O . VAL C 1 69 ? 3.477 -26.791 50.099 1.00 147.52 ? 69 VAL C O 1 +ATOM 4338 C CB . VAL C 1 69 ? 6.527 -26.148 48.974 1.00 76.22 ? 69 VAL C CB 1 +ATOM 4339 C CG1 . VAL C 1 69 ? 5.535 -25.164 48.360 1.00 117.41 ? 69 VAL C CG1 1 +ATOM 4340 C CG2 . VAL C 1 69 ? 7.795 -25.399 49.334 1.00 67.86 ? 69 VAL C CG2 1 +ATOM 4341 N N . THR C 1 70 ? 4.550 -28.524 49.121 1.00 100.83 ? 70 THR C N 1 +ATOM 4342 C CA . THR C 1 70 ? 3.319 -29.185 48.726 1.00 118.14 ? 70 THR C CA 1 +ATOM 4343 C C . THR C 1 70 ? 2.458 -29.576 49.929 1.00 112.55 ? 70 THR C C 1 +ATOM 4344 O O . THR C 1 70 ? 1.229 -29.357 49.932 1.00 118.43 ? 70 THR C O 1 +ATOM 4345 C CB . THR C 1 70 ? 3.632 -30.431 47.892 1.00 149.44 ? 70 THR C CB 1 +ATOM 4346 O OG1 . THR C 1 70 ? 4.464 -30.036 46.794 1.00 159.34 ? 70 THR C OG1 1 +ATOM 4347 C CG2 . THR C 1 70 ? 2.334 -31.085 47.361 1.00 165.24 ? 70 THR C CG2 1 +ATOM 4348 N N . ALA C 1 71 ? 3.086 -30.164 50.948 1.00 103.43 ? 71 ALA C N 1 +ATOM 4349 C CA . ALA C 1 71 ? 2.358 -30.518 52.174 1.00 113.19 ? 71 ALA C CA 1 +ATOM 4350 C C . ALA C 1 71 ? 1.758 -29.280 52.875 1.00 107.26 ? 71 ALA C C 1 +ATOM 4351 O O . ALA C 1 71 ? 0.589 -29.295 53.311 1.00 102.77 ? 71 ALA C O 1 +ATOM 4352 C CB . ALA C 1 71 ? 3.265 -31.261 53.135 1.00 95.84 ? 71 ALA C CB 1 +ATOM 4353 N N . LEU C 1 72 ? 2.539 -28.206 52.934 1.00 96.20 ? 72 LEU C N 1 +ATOM 4354 C CA . LEU C 1 72 ? 2.045 -26.933 53.465 1.00 92.70 ? 72 LEU C CA 1 +ATOM 4355 C C . LEU C 1 72 ? 0.830 -26.399 52.695 1.00 103.52 ? 72 LEU C C 1 +ATOM 4356 O O . LEU C 1 72 ? -0.002 -25.680 53.254 1.00 89.15 ? 72 LEU C O 1 +ATOM 4357 C CB . LEU C 1 72 ? 3.144 -25.868 53.458 1.00 73.27 ? 72 LEU C CB 1 +ATOM 4358 C CG . LEU C 1 72 ? 4.292 -26.160 54.403 1.00 78.53 ? 72 LEU C CG 1 +ATOM 4359 C CD1 . LEU C 1 72 ? 5.455 -25.299 54.015 1.00 92.14 ? 72 LEU C CD1 1 +ATOM 4360 C CD2 . LEU C 1 72 ? 3.916 -25.892 55.848 1.00 106.54 ? 72 LEU C CD2 1 +ATOM 4361 N N . LYS C 1 73 ? 0.729 -26.747 51.415 1.00 108.50 ? 73 LYS C N 1 +ATOM 4362 C CA . LYS C 1 73 ? -0.400 -26.292 50.613 1.00 110.27 ? 73 LYS C CA 1 +ATOM 4363 C C . LYS C 1 73 ? -1.618 -27.182 50.774 1.00 108.37 ? 73 LYS C C 1 +ATOM 4364 O O . LYS C 1 73 ? -2.727 -26.691 50.942 1.00 99.88 ? 73 LYS C O 1 +ATOM 4365 C CB . LYS C 1 73 ? -0.030 -26.242 49.145 1.00 112.98 ? 73 LYS C CB 1 +ATOM 4366 C CG . LYS C 1 73 ? -1.082 -25.546 48.319 1.00 117.26 ? 73 LYS C CG 1 +ATOM 4367 C CD . LYS C 1 73 ? -1.041 -26.075 46.914 1.00 128.27 ? 73 LYS C CD 1 +ATOM 4368 C CE . LYS C 1 73 ? -1.748 -27.439 46.724 1.00 113.54 ? 73 LYS C CE 1 +ATOM 4369 N NZ . LYS C 1 73 ? -3.065 -27.290 46.037 1.00 118.64 ? 73 LYS C NZ 1 +ATOM 4370 N N . ASP C 1 74 ? -1.401 -28.493 50.718 1.00 107.44 ? 74 ASP C N 1 +ATOM 4371 C CA . ASP C 1 74 ? -2.488 -29.460 50.829 1.00 105.89 ? 74 ASP C CA 1 +ATOM 4372 C C . ASP C 1 74 ? -3.247 -29.328 52.155 1.00 112.17 ? 74 ASP C C 1 +ATOM 4373 O O . ASP C 1 74 ? -4.447 -29.628 52.213 1.00 153.03 ? 74 ASP C O 1 +ATOM 4374 C CB . ASP C 1 74 ? -1.960 -30.899 50.681 1.00 108.90 ? 74 ASP C CB 1 +ATOM 4375 C CG . ASP C 1 74 ? -1.456 -31.213 49.265 1.00 113.75 ? 74 ASP C CG 1 +ATOM 4376 O OD1 . ASP C 1 74 ? -1.938 -30.601 48.272 1.00 94.58 ? 74 ASP C OD1 1 +ATOM 4377 O OD2 . ASP C 1 74 ? -0.564 -32.085 49.168 1.00 92.16 ? 74 ASP C OD2 1 +ATOM 4378 N N . SER C 1 75 ? -2.560 -28.866 53.202 1.00 105.22 ? 75 SER C N 1 +ATOM 4379 C CA . SER C 1 75 ? -3.153 -28.728 54.545 1.00 100.66 ? 75 SER C CA 1 +ATOM 4380 C C . SER C 1 75 ? -4.275 -27.697 54.598 1.00 99.11 ? 75 SER C C 1 +ATOM 4381 O O . SER C 1 75 ? -5.157 -27.781 55.454 1.00 118.49 ? 75 SER C O 1 +ATOM 4382 C CB . SER C 1 75 ? -2.088 -28.334 55.571 1.00 94.78 ? 75 SER C CB 1 +ATOM 4383 O OG . SER C 1 75 ? -1.908 -26.928 55.602 1.00 74.44 ? 75 SER C OG 1 +ATOM 4384 N N . ARG C 1 76 ? -4.236 -26.740 53.672 1.00 113.01 ? 76 ARG C N 1 +ATOM 4385 C CA . ARG C 1 76 ? -5.213 -25.648 53.585 1.00 127.88 ? 76 ARG C CA 1 +ATOM 4386 C C . ARG C 1 76 ? -5.141 -24.773 54.811 1.00 123.81 ? 76 ARG C C 1 +ATOM 4387 O O . ARG C 1 76 ? -6.153 -24.278 55.301 1.00 151.08 ? 76 ARG C O 1 +ATOM 4388 C CB . ARG C 1 76 ? -6.633 -26.173 53.374 1.00 134.63 ? 76 ARG C CB 1 +ATOM 4389 C CG . ARG C 1 76 ? -6.836 -26.960 52.085 1.00 146.27 ? 76 ARG C CG 1 +ATOM 4390 C CD . ARG C 1 76 ? -8.288 -27.403 51.957 1.00 158.28 ? 76 ARG C CD 1 +ATOM 4391 N NE . ARG C 1 76 ? -8.639 -28.426 52.944 1.00 158.01 ? 76 ARG C NE 1 +ATOM 4392 C CZ . ARG C 1 76 ? -9.205 -28.192 54.128 1.00 163.26 ? 76 ARG C CZ 1 +ATOM 4393 N NH1 . ARG C 1 76 ? -9.497 -26.955 54.526 1.00 169.25 ? 76 ARG C NH1 1 +ATOM 4394 N NH2 . ARG C 1 76 ? -9.474 -29.212 54.926 1.00 162.64 ? 76 ARG C NH2 1 +ATOM 4395 N N . TRP C 1 77 ? -3.924 -24.623 55.316 1.00 119.06 ? 77 TRP C N 1 +ATOM 4396 C CA . TRP C 1 77 ? -3.632 -23.681 56.380 1.00 126.71 ? 77 TRP C CA 1 +ATOM 4397 C C . TRP C 1 77 ? -2.715 -22.567 55.869 1.00 131.12 ? 77 TRP C C 1 +ATOM 4398 O O . TRP C 1 77 ? -2.785 -21.424 56.328 1.00 107.92 ? 77 TRP C O 1 +ATOM 4399 C CB . TRP C 1 77 ? -2.967 -24.424 57.547 1.00 133.14 ? 77 TRP C CB 1 +ATOM 4400 C CG . TRP C 1 77 ? -3.922 -24.915 58.596 1.00 138.78 ? 77 TRP C CG 1 +ATOM 4401 C CD1 . TRP C 1 77 ? -4.748 -25.992 58.512 1.00 126.17 ? 77 TRP C CD1 1 +ATOM 4402 C CD2 . TRP C 1 77 ? -4.129 -24.349 59.894 1.00 138.39 ? 77 TRP C CD2 1 +ATOM 4403 N NE1 . TRP C 1 77 ? -5.481 -26.116 59.663 1.00 105.52 ? 77 TRP C NE1 1 +ATOM 4404 C CE2 . TRP C 1 77 ? -5.116 -25.117 60.528 1.00 117.70 ? 77 TRP C CE2 1 +ATOM 4405 C CE3 . TRP C 1 77 ? -3.590 -23.247 60.571 1.00 142.52 ? 77 TRP C CE3 1 +ATOM 4406 C CZ2 . TRP C 1 77 ? -5.567 -24.829 61.805 1.00 127.86 ? 77 TRP C CZ2 1 +ATOM 4407 C CZ3 . TRP C 1 77 ? -4.050 -22.959 61.842 1.00 121.48 ? 77 TRP C CZ3 1 +ATOM 4408 C CH2 . TRP C 1 77 ? -5.023 -23.748 62.447 1.00 115.85 ? 77 TRP C CH2 1 +ATOM 4409 N N . PHE C 1 78 ? -1.811 -22.937 54.957 1.00 140.71 ? 78 PHE C N 1 +ATOM 4410 C CA . PHE C 1 78 ? -0.746 -22.053 54.474 1.00 118.35 ? 78 PHE C CA 1 +ATOM 4411 C C . PHE C 1 78 ? -0.838 -21.790 52.960 1.00 121.59 ? 78 PHE C C 1 +ATOM 4412 O O . PHE C 1 78 ? -1.142 -22.700 52.173 1.00 122.56 ? 78 PHE C O 1 +ATOM 4413 C CB . PHE C 1 78 ? 0.622 -22.682 54.743 1.00 104.31 ? 78 PHE C CB 1 +ATOM 4414 C CG . PHE C 1 78 ? 0.865 -23.043 56.174 1.00 101.05 ? 78 PHE C CG 1 +ATOM 4415 C CD1 . PHE C 1 78 ? 1.148 -22.071 57.118 1.00 109.34 ? 78 PHE C CD1 1 +ATOM 4416 C CD2 . PHE C 1 78 ? 0.833 -24.360 56.567 1.00 95.95 ? 78 PHE C CD2 1 +ATOM 4417 C CE1 . PHE C 1 78 ? 1.359 -22.407 58.439 1.00 116.77 ? 78 PHE C CE1 1 +ATOM 4418 C CE2 . PHE C 1 78 ? 1.070 -24.708 57.881 1.00 103.61 ? 78 PHE C CE2 1 +ATOM 4419 C CZ . PHE C 1 78 ? 1.336 -23.732 58.820 1.00 107.60 ? 78 PHE C CZ 1 +ATOM 4420 N N . ILE C 1 79 ? -0.516 -20.557 52.564 1.00 121.92 ? 79 ILE C N 1 +ATOM 4421 C CA . ILE C 1 79 ? -0.176 -20.214 51.179 1.00 108.95 ? 79 ILE C CA 1 +ATOM 4422 C C . ILE C 1 79 ? 1.358 -20.188 51.073 1.00 105.64 ? 79 ILE C C 1 +ATOM 4423 O O . ILE C 1 79 ? 2.005 -19.517 51.880 1.00 73.06 ? 79 ILE C O 1 +ATOM 4424 C CB . ILE C 1 79 ? -0.677 -18.813 50.826 1.00 100.39 ? 79 ILE C CB 1 +ATOM 4425 C CG1 . ILE C 1 79 ? -2.136 -18.643 51.226 1.00 120.59 ? 79 ILE C CG1 1 +ATOM 4426 C CG2 . ILE C 1 79 ? -0.513 -18.545 49.343 1.00 102.76 ? 79 ILE C CG2 1 +ATOM 4427 C CD1 . ILE C 1 79 ? -2.542 -17.195 51.433 1.00 155.24 ? 79 ILE C CD1 1 +ATOM 4428 N N . PRO C 1 80 ? 1.936 -21.003 50.163 1.00 102.55 ? 80 PRO C N 1 +ATOM 4429 C CA . PRO C 1 80 ? 3.379 -20.992 50.094 1.00 90.20 ? 80 PRO C CA 1 +ATOM 4430 C C . PRO C 1 80 ? 3.824 -20.011 49.070 1.00 112.78 ? 80 PRO C C 1 +ATOM 4431 O O . PRO C 1 80 ? 3.184 -19.886 48.013 1.00 114.50 ? 80 PRO C O 1 +ATOM 4432 C CB . PRO C 1 80 ? 3.730 -22.387 49.642 1.00 83.71 ? 80 PRO C CB 1 +ATOM 4433 C CG . PRO C 1 80 ? 2.580 -23.214 50.065 1.00 122.72 ? 80 PRO C CG 1 +ATOM 4434 C CD . PRO C 1 80 ? 1.404 -22.324 49.785 1.00 123.33 ? 80 PRO C CD 1 +ATOM 4435 N N . LEU C 1 81 ? 4.799 -19.196 49.456 1.00 106.84 ? 81 LEU C N 1 +ATOM 4436 C CA . LEU C 1 81 ? 5.363 -18.216 48.565 1.00 79.23 ? 81 LEU C CA 1 +ATOM 4437 C C . LEU C 1 81 ? 6.579 -18.842 47.958 1.00 69.26 ? 81 LEU C C 1 +ATOM 4438 O O . LEU C 1 81 ? 7.287 -19.604 48.651 1.00 59.27 ? 81 LEU C O 1 +ATOM 4439 C CB . LEU C 1 81 ? 5.695 -16.939 49.306 1.00 60.04 ? 81 LEU C CB 1 +ATOM 4440 C CG . LEU C 1 81 ? 4.468 -16.357 49.989 1.00 72.19 ? 81 LEU C CG 1 +ATOM 4441 C CD1 . LEU C 1 81 ? 4.871 -15.146 50.779 1.00 53.10 ? 81 LEU C CD1 1 +ATOM 4442 C CD2 . LEU C 1 81 ? 3.398 -15.974 48.961 1.00 100.26 ? 81 LEU C CD2 1 +ATOM 4443 N N . GLU C 1 82 ? 6.724 -18.614 46.639 1.00 64.20 ? 82 GLU C N 1 +ATOM 4444 C CA . GLU C 1 82 ? 7.774 -19.237 45.837 1.00 62.64 ? 82 GLU C CA 1 +ATOM 4445 C C . GLU C 1 82 ? 9.148 -18.551 46.052 1.00 70.29 ? 82 GLU C C 1 +ATOM 4446 O O . GLU C 1 82 ? 9.360 -17.404 45.676 1.00 35.15 ? 82 GLU C O 1 +ATOM 4447 C CB . GLU C 1 82 ? 7.426 -19.255 44.359 1.00 51.40 ? 82 GLU C CB 1 +ATOM 4448 C CG . GLU C 1 82 ? 8.502 -19.894 43.504 1.00 70.13 ? 82 GLU C CG 1 +ATOM 4449 C CD . GLU C 1 82 ? 8.618 -21.433 43.676 1.00 89.62 ? 82 GLU C CD 1 +ATOM 4450 O OE1 . GLU C 1 82 ? 8.767 -21.965 44.822 1.00 72.83 ? 82 GLU C OE1 1 +ATOM 4451 O OE2 . GLU C 1 82 ? 8.753 -22.120 42.624 1.00 125.51 ? 82 GLU C OE2 1 +ATOM 4452 N N . ARG C 1 83 ? 10.012 -19.265 46.785 1.00 86.67 ? 83 ARG C N 1 +ATOM 4453 C CA . ARG C 1 83 ? 11.364 -18.838 47.041 1.00 68.44 ? 83 ARG C CA 1 +ATOM 4454 C C . ARG C 1 83 ? 12.393 -19.876 46.564 1.00 74.98 ? 83 ARG C C 1 +ATOM 4455 O O . ARG C 1 83 ? 13.544 -19.515 46.322 1.00 109.28 ? 83 ARG C O 1 +ATOM 4456 C CB . ARG C 1 83 ? 11.569 -18.551 48.538 1.00 73.33 ? 83 ARG C CB 1 +ATOM 4457 C CG . ARG C 1 83 ? 10.616 -17.523 49.114 1.00 66.80 ? 83 ARG C CG 1 +ATOM 4458 C CD . ARG C 1 83 ? 10.878 -16.127 48.571 1.00 65.33 ? 83 ARG C CD 1 +ATOM 4459 N NE . ARG C 1 83 ? 10.097 -15.162 49.334 1.00 89.17 ? 83 ARG C NE 1 +ATOM 4460 C CZ . ARG C 1 83 ? 8.917 -14.634 48.962 1.00 124.42 ? 83 ARG C CZ 1 +ATOM 4461 N NH1 . ARG C 1 83 ? 8.413 -14.848 47.747 1.00 107.73 ? 83 ARG C NH1 1 +ATOM 4462 N NH2 . ARG C 1 83 ? 8.267 -13.834 49.809 1.00 136.09 ? 83 ARG C NH2 1 +ATOM 4463 N N . GLN C 1 84 ? 12.020 -21.144 46.404 1.00 67.36 ? 84 GLN C N 1 +ATOM 4464 C CA . GLN C 1 84 ? 12.996 -22.099 45.879 1.00 79.73 ? 84 GLN C CA 1 +ATOM 4465 C C . GLN C 1 84 ? 13.534 -21.626 44.518 1.00 84.68 ? 84 GLN C C 1 +ATOM 4466 O O . GLN C 1 84 ? 14.711 -21.712 44.245 1.00 88.59 ? 84 GLN C O 1 +ATOM 4467 C CB . GLN C 1 84 ? 12.429 -23.524 45.783 1.00 110.94 ? 84 GLN C CB 1 +ATOM 4468 C CG . GLN C 1 84 ? 13.475 -24.630 45.992 1.00 122.78 ? 84 GLN C CG 1 +ATOM 4469 C CD . GLN C 1 84 ? 12.907 -26.039 45.804 1.00 141.50 ? 84 GLN C CD 1 +ATOM 4470 O OE1 . GLN C 1 84 ? 11.756 -26.301 46.130 1.00 110.60 ? 84 GLN C OE1 1 +ATOM 4471 N NE2 . GLN C 1 84 ? 13.709 -26.934 45.237 1.00 156.44 ? 84 GLN C NE2 1 +ATOM 4472 N N . GLY C 1 85 ? 12.671 -21.113 43.654 1.00 93.17 ? 85 GLY C N 1 +ATOM 4473 C CA . GLY C 1 85 ? 13.137 -20.637 42.359 1.00 83.77 ? 85 GLY C CA 1 +ATOM 4474 C C . GLY C 1 85 ? 13.067 -19.118 42.262 1.00 84.99 ? 85 GLY C C 1 +ATOM 4475 O O . GLY C 1 85 ? 12.731 -18.581 41.209 1.00 65.75 ? 85 GLY C O 1 +ATOM 4476 N N . LEU C 1 86 ? 13.465 -18.416 43.323 1.00 81.60 ? 86 LEU C N 1 +ATOM 4477 C CA . LEU C 1 86 ? 13.216 -16.975 43.414 1.00 71.72 ? 86 LEU C CA 1 +ATOM 4478 C C . LEU C 1 86 ? 13.877 -16.242 42.276 1.00 75.25 ? 86 LEU C C 1 +ATOM 4479 O O . LEU C 1 86 ? 13.370 -15.216 41.795 1.00 81.16 ? 86 LEU C O 1 +ATOM 4480 C CB . LEU C 1 86 ? 13.703 -16.412 44.765 1.00 66.23 ? 86 LEU C CB 1 +ATOM 4481 C CG . LEU C 1 86 ? 13.712 -14.900 45.040 1.00 54.42 ? 86 LEU C CG 1 +ATOM 4482 C CD1 . LEU C 1 86 ? 12.341 -14.276 44.903 1.00 62.13 ? 86 LEU C CD1 1 +ATOM 4483 C CD2 . LEU C 1 86 ? 14.250 -14.608 46.432 1.00 53.76 ? 86 LEU C CD2 1 +ATOM 4484 N N . GLN C 1 87 ? 15.044 -16.736 41.872 1.00 84.55 ? 87 GLN C N 1 +ATOM 4485 C CA . GLN C 1 87 ? 15.851 -16.024 40.890 1.00 93.21 ? 87 GLN C CA 1 +ATOM 4486 C C . GLN C 1 87 ? 15.091 -15.885 39.557 1.00 68.77 ? 87 GLN C C 1 +ATOM 4487 O O . GLN C 1 87 ? 15.068 -14.796 38.923 1.00 62.77 ? 87 GLN C O 1 +ATOM 4488 C CB . GLN C 1 87 ? 17.209 -16.718 40.718 1.00 87.36 ? 87 GLN C CB 1 +ATOM 4489 C CG . GLN C 1 87 ? 18.343 -15.741 40.421 1.00 97.39 ? 87 GLN C CG 1 +ATOM 4490 C CD . GLN C 1 87 ? 18.253 -14.451 41.269 1.00 94.08 ? 87 GLN C CD 1 +ATOM 4491 O OE1 . GLN C 1 87 ? 18.349 -14.511 42.500 1.00 98.26 ? 87 GLN C OE1 1 +ATOM 4492 N NE2 . GLN C 1 87 ? 18.176 -13.281 40.606 1.00 64.33 ? 87 GLN C NE2 1 +ATOM 4493 N N . ASN C 1 88 ? 14.433 -16.962 39.166 1.00 51.98 ? 88 ASN C N 1 +ATOM 4494 C CA . ASN C 1 88 ? 13.666 -16.962 37.929 1.00 74.82 ? 88 ASN C CA 1 +ATOM 4495 C C . ASN C 1 88 ? 12.472 -16.027 38.003 1.00 75.68 ? 88 ASN C C 1 +ATOM 4496 O O . ASN C 1 88 ? 12.068 -15.419 36.997 1.00 114.27 ? 88 ASN C O 1 +ATOM 4497 C CB . ASN C 1 88 ? 13.161 -18.361 37.620 1.00 78.77 ? 88 ASN C CB 1 +ATOM 4498 C CG . ASN C 1 88 ? 14.274 -19.369 37.529 1.00 86.89 ? 88 ASN C CG 1 +ATOM 4499 O OD1 . ASN C 1 88 ? 15.344 -19.064 37.027 1.00 77.43 ? 88 ASN C OD1 1 +ATOM 4500 N ND2 . ASN C 1 88 ? 14.038 -20.572 38.064 1.00 121.22 ? 88 ASN C ND2 1 +ATOM 4501 N N . LEU C 1 89 ? 11.900 -15.937 39.190 1.00 62.37 ? 89 LEU C N 1 +ATOM 4502 C CA . LEU C 1 89 ? 10.723 -15.130 39.399 1.00 59.69 ? 89 LEU C CA 1 +ATOM 4503 C C . LEU C 1 89 ? 11.097 -13.683 39.217 1.00 70.55 ? 89 LEU C C 1 +ATOM 4504 O O . LEU C 1 89 ? 10.427 -12.911 38.505 1.00 93.71 ? 89 LEU C O 1 +ATOM 4505 C CB . LEU C 1 89 ? 10.246 -15.372 40.812 1.00 59.18 ? 89 LEU C CB 1 +ATOM 4506 C CG . LEU C 1 89 ? 8.768 -15.205 41.114 1.00 55.36 ? 89 LEU C CG 1 +ATOM 4507 C CD1 . LEU C 1 89 ? 8.568 -14.074 42.088 1.00 48.62 ? 89 LEU C CD1 1 +ATOM 4508 C CD2 . LEU C 1 89 ? 7.942 -14.984 39.861 1.00 53.43 ? 89 LEU C CD2 1 +ATOM 4509 N N . LEU C 1 90 ? 12.266 -13.332 39.739 1.00 76.65 ? 90 LEU C N 1 +ATOM 4510 C CA . LEU C 1 90 ? 12.767 -11.951 39.613 1.00 90.57 ? 90 LEU C CA 1 +ATOM 4511 C C . LEU C 1 90 ? 13.162 -11.603 38.162 1.00 94.08 ? 90 LEU C C 1 +ATOM 4512 O O . LEU C 1 90 ? 13.039 -10.449 37.713 1.00 66.12 ? 90 LEU C O 1 +ATOM 4513 C CB . LEU C 1 90 ? 13.965 -11.741 40.541 1.00 83.42 ? 90 LEU C CB 1 +ATOM 4514 C CG . LEU C 1 90 ? 13.676 -11.976 42.015 1.00 69.82 ? 90 LEU C CG 1 +ATOM 4515 C CD1 . LEU C 1 90 ? 14.979 -12.193 42.754 1.00 51.10 ? 90 LEU C CD1 1 +ATOM 4516 C CD2 . LEU C 1 90 ? 12.891 -10.791 42.564 1.00 96.05 ? 90 LEU C CD2 1 +ATOM 4517 N N . ASN C 1 91 ? 13.632 -12.618 37.443 1.00 83.54 ? 91 ASN C N 1 +ATOM 4518 C CA . ASN C 1 91 ? 13.972 -12.461 36.053 1.00 83.13 ? 91 ASN C CA 1 +ATOM 4519 C C . ASN C 1 91 ? 12.735 -12.158 35.205 1.00 94.69 ? 91 ASN C C 1 +ATOM 4520 O O . ASN C 1 91 ? 12.745 -11.254 34.364 1.00 75.37 ? 91 ASN C O 1 +ATOM 4521 C CB . ASN C 1 91 ? 14.689 -13.718 35.549 1.00 74.10 ? 91 ASN C CB 1 +ATOM 4522 C CG . ASN C 1 91 ? 15.993 -13.385 34.912 1.00 98.53 ? 91 ASN C CG 1 +ATOM 4523 O OD1 . ASN C 1 91 ? 16.764 -12.570 35.484 1.00 134.54 ? 91 ASN C OD1 1 +ATOM 4524 N ND2 . ASN C 1 91 ? 16.153 -13.773 33.632 1.00 101.83 ? 91 ASN C ND2 1 +ATOM 4525 N N . GLU C 1 92 ? 11.695 -12.974 35.360 1.00 113.30 ? 92 GLU C N 1 +ATOM 4526 C CA . GLU C 1 92 ? 10.470 -12.766 34.594 1.00 103.16 ? 92 GLU C CA 1 +ATOM 4527 C C . GLU C 1 92 ? 9.946 -11.358 34.860 1.00 103.98 ? 92 GLU C C 1 +ATOM 4528 O O . GLU C 1 92 ? 9.357 -10.714 33.988 1.00 67.83 ? 92 GLU C O 1 +ATOM 4529 C CB . GLU C 1 92 ? 9.421 -13.834 34.941 1.00 90.30 ? 92 GLU C CB 1 +ATOM 4530 C CG . GLU C 1 92 ? 9.421 -15.029 34.004 1.00 101.43 ? 92 GLU C CG 1 +ATOM 4531 C CD . GLU C 1 92 ? 9.320 -14.644 32.511 1.00 113.10 ? 92 GLU C CD 1 +ATOM 4532 O OE1 . GLU C 1 92 ? 8.334 -13.981 32.072 1.00 76.42 ? 92 GLU C OE1 1 +ATOM 4533 O OE2 . GLU C 1 92 ? 10.211 -15.078 31.743 1.00 127.90 ? 92 GLU C OE2 1 +ATOM 4534 N N . ARG C 1 93 ? 10.113 -10.911 36.098 1.00 106.58 ? 93 ARG C N 1 +ATOM 4535 C CA . ARG C 1 93 ? 9.625 -9.604 36.477 1.00 115.05 ? 93 ARG C CA 1 +ATOM 4536 C C . ARG C 1 93 ? 10.464 -8.518 35.808 1.00 112.54 ? 93 ARG C C 1 +ATOM 4537 O O . ARG C 1 93 ? 9.938 -7.462 35.432 1.00 89.40 ? 93 ARG C O 1 +ATOM 4538 C CB . ARG C 1 93 ? 9.573 -9.488 38.008 1.00 105.89 ? 93 ARG C CB 1 +ATOM 4539 C CG . ARG C 1 93 ? 8.459 -10.360 38.592 1.00 102.64 ? 93 ARG C CG 1 +ATOM 4540 C CD . ARG C 1 93 ? 8.557 -10.558 40.088 1.00 108.72 ? 93 ARG C CD 1 +ATOM 4541 N NE . ARG C 1 93 ? 7.635 -9.693 40.811 1.00 77.63 ? 93 ARG C NE 1 +ATOM 4542 C CZ . ARG C 1 93 ? 7.947 -8.496 41.307 1.00 58.61 ? 93 ARG C CZ 1 +ATOM 4543 N NH1 . ARG C 1 93 ? 9.161 -7.982 41.192 1.00 60.34 ? 93 ARG C NH1 1 +ATOM 4544 N NH2 . ARG C 1 93 ? 7.038 -7.863 42.007 1.00 56.99 ? 93 ARG C NH2 1 +ATOM 4545 N N . LYS C 1 94 ? 11.754 -8.788 35.614 1.00 106.62 ? 94 LYS C N 1 +ATOM 4546 C CA . LYS C 1 94 ? 12.609 -7.858 34.858 1.00 89.27 ? 94 LYS C CA 1 +ATOM 4547 C C . LYS C 1 94 ? 12.133 -7.755 33.408 1.00 74.77 ? 94 LYS C C 1 +ATOM 4548 O O . LYS C 1 94 ? 12.066 -6.648 32.849 1.00 56.47 ? 94 LYS C O 1 +ATOM 4549 C CB . LYS C 1 94 ? 14.052 -8.329 34.845 1.00 85.01 ? 94 LYS C CB 1 +ATOM 4550 C CG . LYS C 1 94 ? 14.918 -7.866 36.001 1.00 87.01 ? 94 LYS C CG 1 +ATOM 4551 C CD . LYS C 1 94 ? 16.263 -8.576 35.953 1.00 97.39 ? 94 LYS C CD 1 +ATOM 4552 C CE . LYS C 1 94 ? 17.344 -7.852 36.737 1.00 101.16 ? 94 LYS C CE 1 +ATOM 4553 N NZ . LYS C 1 94 ? 18.516 -8.749 36.938 1.00 113.18 ? 94 LYS C NZ 1 +ATOM 4554 N N . ILE C 1 95 ? 11.721 -8.895 32.843 1.00 60.27 ? 95 ILE C N 1 +ATOM 4555 C CA . ILE C 1 95 ? 11.332 -8.917 31.441 1.00 51.11 ? 95 ILE C CA 1 +ATOM 4556 C C . ILE C 1 95 ? 10.021 -8.224 31.253 1.00 54.46 ? 95 ILE C C 1 +ATOM 4557 O O . ILE C 1 95 ? 9.809 -7.517 30.224 1.00 31.50 ? 95 ILE C O 1 +ATOM 4558 C CB . ILE C 1 95 ? 11.190 -10.322 30.871 1.00 47.46 ? 95 ILE C CB 1 +ATOM 4559 C CG1 . ILE C 1 95 ? 12.402 -11.190 31.217 1.00 60.92 ? 95 ILE C CG1 1 +ATOM 4560 C CG2 . ILE C 1 95 ? 11.112 -10.192 29.353 1.00 43.72 ? 95 ILE C CG2 1 +ATOM 4561 C CD1 . ILE C 1 95 ? 12.547 -12.494 30.424 1.00 54.26 ? 95 ILE C CD1 1 +ATOM 4562 N N . ILE C 1 96 ? 9.125 -8.460 32.242 1.00 54.70 ? 96 ILE C N 1 +ATOM 4563 C CA . ILE C 1 96 ? 7.837 -7.771 32.296 1.00 51.96 ? 96 ILE C CA 1 +ATOM 4564 C C . ILE C 1 96 ? 8.023 -6.268 32.306 1.00 45.60 ? 96 ILE C C 1 +ATOM 4565 O O . ILE C 1 96 ? 7.574 -5.570 31.387 1.00 38.05 ? 96 ILE C O 1 +ATOM 4566 C CB . ILE C 1 96 ? 7.017 -8.156 33.509 1.00 45.22 ? 96 ILE C CB 1 +ATOM 4567 C CG1 . ILE C 1 96 ? 6.559 -9.612 33.411 1.00 51.48 ? 96 ILE C CG1 1 +ATOM 4568 C CG2 . ILE C 1 96 ? 5.768 -7.281 33.550 1.00 50.62 ? 96 ILE C CG2 1 +ATOM 4569 C CD1 . ILE C 1 96 ? 5.661 -10.056 34.558 1.00 53.11 ? 96 ILE C CD1 1 +ATOM 4570 N N . ARG C 1 97 ? 8.740 -5.792 33.306 1.00 46.14 ? 97 ARG C N 1 +ATOM 4571 C CA . ARG C 1 97 ? 8.959 -4.357 33.446 1.00 60.97 ? 97 ARG C CA 1 +ATOM 4572 C C . ARG C 1 97 ? 9.633 -3.756 32.205 1.00 71.86 ? 97 ARG C C 1 +ATOM 4573 O O . ARG C 1 97 ? 9.419 -2.579 31.877 1.00 99.30 ? 97 ARG C O 1 +ATOM 4574 C CB . ARG C 1 97 ? 9.790 -4.046 34.701 1.00 70.93 ? 97 ARG C CB 1 +ATOM 4575 C CG . ARG C 1 97 ? 8.989 -3.538 35.897 1.00 67.73 ? 97 ARG C CG 1 +ATOM 4576 C CD . ARG C 1 97 ? 9.902 -3.199 37.079 1.00 71.57 ? 97 ARG C CD 1 +ATOM 4577 N NE . ARG C 1 97 ? 10.308 -4.360 37.868 1.00 75.84 ? 97 ARG C NE 1 +ATOM 4578 C CZ . ARG C 1 97 ? 9.717 -4.760 38.989 1.00 83.21 ? 97 ARG C CZ 1 +ATOM 4579 N NH1 . ARG C 1 97 ? 8.711 -4.080 39.501 1.00 65.01 ? 97 ARG C NH1 1 +ATOM 4580 N NH2 . ARG C 1 97 ? 10.129 -5.878 39.583 1.00 112.89 ? 97 ARG C NH2 1 +ATOM 4581 N N . ALA C 1 98 ? 10.473 -4.536 31.534 1.00 69.31 ? 98 ALA C N 1 +ATOM 4582 C CA . ALA C 1 98 ? 11.156 -4.035 30.366 1.00 79.49 ? 98 ALA C CA 1 +ATOM 4583 C C . ALA C 1 98 ? 10.179 -3.978 29.191 1.00 82.95 ? 98 ALA C C 1 +ATOM 4584 O O . ALA C 1 98 ? 10.363 -3.176 28.258 1.00 59.44 ? 98 ALA C O 1 +ATOM 4585 C CB . ALA C 1 98 ? 12.353 -4.919 30.056 1.00 107.17 ? 98 ALA C CB 1 +ATOM 4586 N N . ALA C 1 99 ? 9.171 -4.867 29.220 1.00 87.05 ? 99 ALA C N 1 +ATOM 4587 C CA . ALA C 1 99 ? 8.135 -4.983 28.142 1.00 78.44 ? 99 ALA C CA 1 +ATOM 4588 C C . ALA C 1 99 ? 7.173 -3.839 28.101 1.00 86.02 ? 99 ALA C C 1 +ATOM 4589 O O . ALA C 1 99 ? 7.054 -3.138 27.089 1.00 147.84 ? 99 ALA C O 1 +ATOM 4590 C CB . ALA C 1 99 ? 7.334 -6.222 28.316 1.00 65.57 ? 99 ALA C CB 1 +ATOM 4591 N N . GLN C 1 100 ? 6.665 -3.497 29.274 1.00 106.89 ? 100 GLN C N 1 +ATOM 4592 C CA . GLN C 1 100 ? 5.575 -2.526 29.357 1.00 121.85 ? 100 GLN C CA 1 +ATOM 4593 C C . GLN C 1 100 ? 5.937 -1.114 29.864 1.00 119.50 ? 100 GLN C C 1 +ATOM 4594 O O . GLN C 1 100 ? 5.048 -0.280 30.076 1.00 120.70 ? 100 GLN C O 1 +ATOM 4595 C CB . GLN C 1 100 ? 4.448 -3.111 30.202 1.00 115.25 ? 100 GLN C CB 1 +ATOM 4596 C CG . GLN C 1 100 ? 4.893 -3.784 31.484 1.00 93.22 ? 100 GLN C CG 1 +ATOM 4597 C CD . GLN C 1 100 ? 3.929 -4.862 31.914 1.00 79.36 ? 100 GLN C CD 1 +ATOM 4598 O OE1 . GLN C 1 100 ? 3.725 -5.886 31.216 1.00 70.26 ? 100 GLN C OE1 1 +ATOM 4599 N NE2 . GLN C 1 100 ? 3.393 -4.688 33.105 1.00 70.48 ? 100 GLN C NE2 1 +ATOM 4600 N N . GLU C 1 101 ? 7.229 -0.837 30.037 1.00 107.44 ? 101 GLU C N 1 +ATOM 4601 C CA . GLU C 1 101 ? 7.662 0.457 30.573 1.00 106.81 ? 101 GLU C CA 1 +ATOM 4602 C C . GLU C 1 101 ? 7.396 1.609 29.607 1.00 108.86 ? 101 GLU C C 1 +ATOM 4603 O O . GLU C 1 101 ? 7.283 2.765 30.029 1.00 83.23 ? 101 GLU C O 1 +ATOM 4604 C CB . GLU C 1 101 ? 9.143 0.423 30.956 1.00 114.01 ? 101 GLU C CB 1 +ATOM 4605 C CG . GLU C 1 101 ? 10.074 -0.086 29.861 1.00 110.43 ? 101 GLU C CG 1 +ATOM 4606 C CD . GLU C 1 101 ? 11.537 -0.029 30.272 1.00 116.30 ? 101 GLU C CD 1 +ATOM 4607 O OE1 . GLU C 1 101 ? 11.814 0.100 31.488 1.00 111.16 ? 101 GLU C OE1 1 +ATOM 4608 O OE2 . GLU C 1 101 ? 12.418 -0.070 29.379 1.00 130.49 ? 101 GLU C OE2 1 +ATOM 4609 N N . ASN C 1 102 ? 7.280 1.301 28.317 1.00 110.52 ? 102 ASN C N 1 +ATOM 4610 C CA . ASN C 1 102 ? 7.075 2.338 27.315 1.00 106.47 ? 102 ASN C CA 1 +ATOM 4611 C C . ASN C 1 102 ? 5.612 2.584 26.990 1.00 110.33 ? 102 ASN C C 1 +ATOM 4612 O O . ASN C 1 102 ? 5.296 3.488 26.209 1.00 120.28 ? 102 ASN C O 1 +ATOM 4613 C CB . ASN C 1 102 ? 7.813 1.982 26.042 1.00 103.72 ? 102 ASN C CB 1 +ATOM 4614 C CG . ASN C 1 102 ? 9.305 2.105 26.199 1.00 119.47 ? 102 ASN C CG 1 +ATOM 4615 O OD1 . ASN C 1 102 ? 9.869 3.216 26.158 1.00 124.50 ? 102 ASN C OD1 1 +ATOM 4616 N ND2 . ASN C 1 102 ? 9.961 0.971 26.414 1.00 129.46 ? 102 ASN C ND2 1 +ATOM 4617 N N . GLY C 1 103 ? 4.715 1.816 27.604 1.00 95.13 ? 103 GLY C N 1 +ATOM 4618 C CA . GLY C 1 103 ? 3.289 2.003 27.371 1.00 94.89 ? 103 GLY C CA 1 +ATOM 4619 C C . GLY C 1 103 ? 2.887 1.812 25.918 1.00 98.95 ? 103 GLY C C 1 +ATOM 4620 O O . GLY C 1 103 ? 1.963 2.468 25.409 1.00 112.13 ? 103 GLY C O 1 +ATOM 4621 N N . THR C 1 104 ? 3.581 0.914 25.239 1.00 84.76 ? 104 THR C N 1 +ATOM 4622 C CA . THR C 1 104 ? 3.131 0.470 23.945 1.00 81.76 ? 104 THR C CA 1 +ATOM 4623 C C . THR C 1 104 ? 2.407 -0.866 24.089 1.00 77.74 ? 104 THR C C 1 +ATOM 4624 O O . THR C 1 104 ? 1.543 -1.177 23.281 1.00 100.47 ? 104 THR C O 1 +ATOM 4625 C CB . THR C 1 104 ? 4.291 0.368 22.925 1.00 73.89 ? 104 THR C CB 1 +ATOM 4626 O OG1 . THR C 1 104 ? 5.220 -0.650 23.326 1.00 69.29 ? 104 THR C OG1 1 +ATOM 4627 C CG2 . THR C 1 104 ? 4.994 1.705 22.787 1.00 63.21 ? 104 THR C CG2 1 +ATOM 4628 N N . VAL C 1 105 ? 2.732 -1.640 25.116 1.00 77.46 ? 105 VAL C N 1 +ATOM 4629 C CA . VAL C 1 105 ? 2.234 -3.025 25.202 1.00 104.83 ? 105 VAL C CA 1 +ATOM 4630 C C . VAL C 1 105 ? 0.713 -3.029 25.278 1.00 116.52 ? 105 VAL C C 1 +ATOM 4631 O O . VAL C 1 105 ? 0.105 -2.164 25.927 1.00 100.08 ? 105 VAL C O 1 +ATOM 4632 C CB . VAL C 1 105 ? 2.866 -3.844 26.380 1.00 132.48 ? 105 VAL C CB 1 +ATOM 4633 C CG1 . VAL C 1 105 ? 1.871 -4.832 26.988 1.00 103.04 ? 105 VAL C CG1 1 +ATOM 4634 C CG2 . VAL C 1 105 ? 4.131 -4.591 25.916 1.00 142.84 ? 105 VAL C CG2 1 +ATOM 4635 N N . ALA C 1 106 ? 0.126 -3.998 24.575 1.00 126.38 ? 106 ALA C N 1 +ATOM 4636 C CA . ALA C 1 106 ? -1.313 -4.077 24.366 1.00 125.76 ? 106 ALA C CA 1 +ATOM 4637 C C . ALA C 1 106 ? -2.043 -4.256 25.690 1.00 157.66 ? 106 ALA C C 1 +ATOM 4638 O O . ALA C 1 106 ? -1.644 -5.071 26.526 1.00 155.51 ? 106 ALA C O 1 +ATOM 4639 C CB . ALA C 1 106 ? -1.635 -5.226 23.423 1.00 113.42 ? 106 ALA C CB 1 +ATOM 4640 N N . ILE C 1 107 ? -3.115 -3.487 25.871 1.00 170.99 ? 107 ILE C N 1 +ATOM 4641 C CA . ILE C 1 107 ? -3.834 -3.427 27.150 1.00 160.80 ? 107 ILE C CA 1 +ATOM 4642 C C . ILE C 1 107 ? -4.379 -4.803 27.598 1.00 139.79 ? 107 ILE C C 1 +ATOM 4643 O O . ILE C 1 107 ? -4.471 -5.093 28.790 1.00 110.41 ? 107 ILE C O 1 +ATOM 4644 C CB . ILE C 1 107 ? -4.977 -2.381 27.077 1.00 130.46 ? 107 ILE C CB 1 +ATOM 4645 C CG1 . ILE C 1 107 ? -5.540 -2.087 28.474 1.00 123.85 ? 107 ILE C CG1 1 +ATOM 4646 C CG2 . ILE C 1 107 ? -6.079 -2.853 26.136 1.00 123.21 ? 107 ILE C CG2 1 +ATOM 4647 C CD1 . ILE C 1 107 ? -4.521 -1.592 29.483 1.00 108.22 ? 107 ILE C CD1 1 +ATOM 4648 N N . ASN C 1 108 ? -4.716 -5.648 26.629 1.00 139.11 ? 108 ASN C N 1 +ATOM 4649 C CA . ASN C 1 108 ? -5.136 -7.029 26.900 1.00 139.17 ? 108 ASN C CA 1 +ATOM 4650 C C . ASN C 1 108 ? -3.970 -7.881 27.386 1.00 133.43 ? 108 ASN C C 1 +ATOM 4651 O O . ASN C 1 108 ? -4.137 -8.777 28.214 1.00 146.55 ? 108 ASN C O 1 +ATOM 4652 C CB . ASN C 1 108 ? -5.707 -7.671 25.633 1.00 165.72 ? 108 ASN C CB 1 +ATOM 4653 C CG . ASN C 1 108 ? -6.364 -6.659 24.710 1.00 194.14 ? 108 ASN C CG 1 +ATOM 4654 O OD1 . ASN C 1 108 ? -7.543 -6.350 24.855 1.00 221.37 ? 108 ASN C OD1 1 +ATOM 4655 N ND2 . ASN C 1 108 ? -5.599 -6.141 23.750 1.00 201.00 ? 108 ASN C ND2 1 +ATOM 4656 N N . ASN C 1 109 ? -2.790 -7.601 26.845 1.00 116.14 ? 109 ASN C N 1 +ATOM 4657 C CA . ASN C 1 109 ? -1.596 -8.390 27.112 1.00 135.87 ? 109 ASN C CA 1 +ATOM 4658 C C . ASN C 1 109 ? -0.843 -7.941 28.373 1.00 141.33 ? 109 ASN C C 1 +ATOM 4659 O O . ASN C 1 109 ? -0.011 -8.691 28.912 1.00 120.71 ? 109 ASN C O 1 +ATOM 4660 C CB . ASN C 1 109 ? -0.659 -8.319 25.904 1.00 143.92 ? 109 ASN C CB 1 +ATOM 4661 C CG . ASN C 1 109 ? -0.460 -9.664 25.237 1.00 154.70 ? 109 ASN C CG 1 +ATOM 4662 O OD1 . ASN C 1 109 ? 0.639 -10.225 25.267 1.00 127.28 ? 109 ASN C OD1 1 +ATOM 4663 N ND2 . ASN C 1 109 ? -1.534 -10.217 24.680 1.00 163.41 ? 109 ASN C ND2 1 +ATOM 4664 N N . ARG C 1 110 ? -1.155 -6.729 28.838 1.00 134.60 ? 110 ARG C N 1 +ATOM 4665 C CA . ARG C 1 110 ? -0.446 -6.077 29.958 1.00 115.13 ? 110 ARG C CA 1 +ATOM 4666 C C . ARG C 1 110 ? -0.449 -6.941 31.229 1.00 95.66 ? 110 ARG C C 1 +ATOM 4667 O O . ARG C 1 110 ? -1.482 -7.511 31.592 1.00 100.97 ? 110 ARG C O 1 +ATOM 4668 C CB . ARG C 1 110 ? -1.117 -4.732 30.263 1.00 95.94 ? 110 ARG C CB 1 +ATOM 4669 C CG . ARG C 1 110 ? -0.229 -3.734 30.966 1.00 103.62 ? 110 ARG C CG 1 +ATOM 4670 C CD . ARG C 1 110 ? -0.549 -2.315 30.538 1.00 113.11 ? 110 ARG C CD 1 +ATOM 4671 N NE . ARG C 1 110 ? -1.586 -1.717 31.385 1.00 111.13 ? 110 ARG C NE 1 +ATOM 4672 C CZ . ARG C 1 110 ? -1.431 -0.615 32.127 1.00 125.89 ? 110 ARG C CZ 1 +ATOM 4673 N NH1 . ARG C 1 110 ? -0.270 0.054 32.159 1.00 126.31 ? 110 ARG C NH1 1 +ATOM 4674 N NH2 . ARG C 1 110 ? -2.461 -0.156 32.836 1.00 130.53 ? 110 ARG C NH2 1 +ATOM 4675 N N . ILE C 1 111 ? 0.695 -7.045 31.896 1.00 77.73 ? 111 ILE C N 1 +ATOM 4676 C CA . ILE C 1 111 ? 0.757 -7.763 33.168 1.00 78.02 ? 111 ILE C CA 1 +ATOM 4677 C C . ILE C 1 111 ? 0.991 -6.787 34.290 1.00 85.97 ? 111 ILE C C 1 +ATOM 4678 O O . ILE C 1 111 ? 2.041 -6.161 34.339 1.00 86.88 ? 111 ILE C O 1 +ATOM 4679 C CB . ILE C 1 111 ? 1.882 -8.808 33.207 1.00 77.54 ? 111 ILE C CB 1 +ATOM 4680 C CG1 . ILE C 1 111 ? 1.606 -9.901 32.166 1.00 100.34 ? 111 ILE C CG1 1 +ATOM 4681 C CG2 . ILE C 1 111 ? 1.994 -9.419 34.601 1.00 62.59 ? 111 ILE C CG2 1 +ATOM 4682 C CD1 . ILE C 1 111 ? 2.776 -10.834 31.895 1.00 109.33 ? 111 ILE C CD1 1 +ATOM 4683 N N . PRO C 1 112 ? 0.022 -6.668 35.212 1.00 104.55 ? 112 PRO C N 1 +ATOM 4684 C CA . PRO C 1 112 ? 0.165 -5.718 36.301 1.00 98.96 ? 112 PRO C CA 1 +ATOM 4685 C C . PRO C 1 112 ? 1.079 -6.283 37.393 1.00 91.10 ? 112 PRO C C 1 +ATOM 4686 O O . PRO C 1 112 ? 0.875 -7.414 37.862 1.00 66.67 ? 112 PRO C O 1 +ATOM 4687 C CB . PRO C 1 112 ? -1.274 -5.555 36.792 1.00 99.29 ? 112 PRO C CB 1 +ATOM 4688 C CG . PRO C 1 112 ? -1.900 -6.897 36.543 1.00 92.21 ? 112 PRO C CG 1 +ATOM 4689 C CD . PRO C 1 112 ? -1.186 -7.507 35.369 1.00 97.61 ? 112 PRO C CD 1 +ATOM 4690 N N . LEU C 1 113 ? 2.056 -5.483 37.799 1.00 102.74 ? 113 LEU C N 1 +ATOM 4691 C CA . LEU C 1 113 ? 3.071 -5.926 38.741 1.00 122.50 ? 113 LEU C CA 1 +ATOM 4692 C C . LEU C 1 113 ? 2.904 -5.308 40.114 1.00 110.67 ? 113 LEU C C 1 +ATOM 4693 O O . LEU C 1 113 ? 2.654 -4.105 40.279 1.00 113.31 ? 113 LEU C O 1 +ATOM 4694 C CB . LEU C 1 113 ? 4.477 -5.628 38.215 1.00 130.39 ? 113 LEU C CB 1 +ATOM 4695 C CG . LEU C 1 113 ? 5.064 -6.694 37.299 1.00 125.12 ? 113 LEU C CG 1 +ATOM 4696 C CD1 . LEU C 1 113 ? 6.482 -6.270 36.957 1.00 119.08 ? 113 LEU C CD1 1 +ATOM 4697 C CD2 . LEU C 1 113 ? 5.054 -8.087 37.921 1.00 117.01 ? 113 LEU C CD2 1 +ATOM 4698 N N . GLN C 1 114 ? 3.150 -6.148 41.099 1.00 107.30 ? 114 GLN C N 1 +ATOM 4699 C CA . GLN C 1 114 ? 2.844 -5.843 42.468 1.00 130.57 ? 114 GLN C CA 1 +ATOM 4700 C C . GLN C 1 114 ? 3.977 -6.410 43.275 1.00 127.97 ? 114 GLN C C 1 +ATOM 4701 O O . GLN C 1 114 ? 4.629 -7.359 42.826 1.00 187.62 ? 114 GLN C O 1 +ATOM 4702 C CB . GLN C 1 114 ? 1.551 -6.536 42.846 1.00 119.49 ? 114 GLN C CB 1 +ATOM 4703 C CG . GLN C 1 114 ? 0.757 -5.810 43.887 1.00 112.02 ? 114 GLN C CG 1 +ATOM 4704 C CD . GLN C 1 114 ? -0.080 -6.777 44.657 1.00 128.32 ? 114 GLN C CD 1 +ATOM 4705 O OE1 . GLN C 1 114 ? -0.515 -7.804 44.115 1.00 112.17 ? 114 GLN C OE1 1 +ATOM 4706 N NE2 . GLN C 1 114 ? -0.319 -6.473 45.937 1.00 174.58 ? 114 GLN C NE2 1 +ATOM 4707 N N . SER C 1 115 ? 4.298 -5.758 44.385 1.00 108.23 ? 115 SER C N 1 +ATOM 4708 C CA . SER C 1 115 ? 5.485 -6.109 45.157 1.00 114.96 ? 115 SER C CA 1 +ATOM 4709 C C . SER C 1 115 ? 5.368 -7.551 45.569 1.00 106.36 ? 115 SER C C 1 +ATOM 4710 O O . SER C 1 115 ? 4.249 -8.110 45.616 1.00 111.09 ? 115 SER C O 1 +ATOM 4711 C CB . SER C 1 115 ? 5.604 -5.220 46.397 1.00 128.18 ? 115 SER C CB 1 +ATOM 4712 O OG . SER C 1 115 ? 4.374 -5.177 47.116 1.00 138.82 ? 115 SER C OG 1 +ATOM 4713 N N . LEU C 1 116 ? 6.497 -8.188 45.858 1.00 93.08 ? 116 LEU C N 1 +ATOM 4714 C CA . LEU C 1 116 ? 6.445 -9.644 46.013 1.00 128.21 ? 116 LEU C CA 1 +ATOM 4715 C C . LEU C 1 116 ? 5.821 -9.936 47.359 1.00 121.66 ? 116 LEU C C 1 +ATOM 4716 O O . LEU C 1 116 ? 6.215 -9.323 48.340 1.00 122.32 ? 116 LEU C O 1 +ATOM 4717 C CB . LEU C 1 116 ? 7.831 -10.280 45.953 1.00 147.73 ? 116 LEU C CB 1 +ATOM 4718 C CG . LEU C 1 116 ? 8.571 -10.230 44.608 1.00 123.11 ? 116 LEU C CG 1 +ATOM 4719 C CD1 . LEU C 1 116 ? 9.513 -9.018 44.537 1.00 118.14 ? 116 LEU C CD1 1 +ATOM 4720 C CD2 . LEU C 1 116 ? 9.321 -11.533 44.426 1.00 82.53 ? 116 LEU C CD2 1 +ATOM 4721 N N . THR C 1 117 ? 4.756 -10.733 47.367 1.00 139.19 ? 117 THR C N 1 +ATOM 4722 C CA . THR C 1 117 ? 4.010 -11.016 48.592 1.00 117.81 ? 117 THR C CA 1 +ATOM 4723 C C . THR C 1 117 ? 5.018 -11.579 49.560 1.00 111.62 ? 117 THR C C 1 +ATOM 4724 O O . THR C 1 117 ? 5.781 -12.468 49.188 1.00 92.80 ? 117 THR C O 1 +ATOM 4725 C CB . THR C 1 117 ? 2.880 -12.049 48.359 1.00 114.49 ? 117 THR C CB 1 +ATOM 4726 O OG1 . THR C 1 117 ? 2.002 -11.593 47.322 1.00 89.39 ? 117 THR C OG1 1 +ATOM 4727 C CG2 . THR C 1 117 ? 2.070 -12.250 49.621 1.00 112.74 ? 117 THR C CG2 1 +ATOM 4728 N N . ALA C 1 118 ? 4.969 -11.095 50.799 1.00 94.19 ? 118 ALA C N 1 +ATOM 4729 C CA . ALA C 1 118 ? 5.998 -11.407 51.792 1.00 73.15 ? 118 ALA C CA 1 +ATOM 4730 C C . ALA C 1 118 ? 5.462 -12.207 52.948 1.00 82.05 ? 118 ALA C C 1 +ATOM 4731 O O . ALA C 1 118 ? 4.354 -11.948 53.443 1.00 137.65 ? 118 ALA C O 1 +ATOM 4732 C CB . ALA C 1 118 ? 6.603 -10.140 52.316 1.00 51.90 ? 118 ALA C CB 1 +ATOM 4733 N N . ALA C 1 119 ? 6.281 -13.133 53.418 1.00 94.07 ? 119 ALA C N 1 +ATOM 4734 C CA . ALA C 1 119 ? 5.857 -14.129 54.407 1.00 126.63 ? 119 ALA C CA 1 +ATOM 4735 C C . ALA C 1 119 ? 6.082 -13.616 55.809 1.00 131.20 ? 119 ALA C C 1 +ATOM 4736 O O . ALA C 1 119 ? 6.958 -12.762 56.007 1.00 123.68 ? 119 ALA C O 1 +ATOM 4737 C CB . ALA C 1 119 ? 6.628 -15.424 54.204 1.00 133.37 ? 119 ALA C CB 1 +ATOM 4738 N N . ASN C 1 120 ? 5.311 -14.131 56.775 1.00 111.89 ? 120 ASN C N 1 +ATOM 4739 C CA . ASN C 1 120 ? 5.557 -13.781 58.163 1.00 128.81 ? 120 ASN C CA 1 +ATOM 4740 C C . ASN C 1 120 ? 6.372 -14.825 58.898 1.00 129.04 ? 120 ASN C C 1 +ATOM 4741 O O . ASN C 1 120 ? 7.308 -14.504 59.659 1.00 127.30 ? 120 ASN C O 1 +ATOM 4742 C CB . ASN C 1 120 ? 4.274 -13.539 58.937 1.00 140.57 ? 120 ASN C CB 1 +ATOM 4743 C CG . ASN C 1 120 ? 4.549 -13.063 60.371 1.00 196.00 ? 120 ASN C CG 1 +ATOM 4744 O OD1 . ASN C 1 120 ? 3.889 -13.515 61.299 1.00 267.60 ? 120 ASN C OD1 1 +ATOM 4745 N ND2 . ASN C 1 120 ? 5.585 -12.216 60.567 1.00 186.54 ? 120 ASN C ND2 1 +ATOM 4746 N N . ILE C 1 121 ? 5.982 -16.078 58.740 1.00 104.34 ? 121 ILE C N 1 +ATOM 4747 C CA . ILE C 1 121 ? 6.782 -17.154 59.306 1.00 132.26 ? 121 ILE C CA 1 +ATOM 4748 C C . ILE C 1 121 ? 7.404 -17.898 58.148 1.00 143.15 ? 121 ILE C C 1 +ATOM 4749 O O . ILE C 1 121 ? 6.813 -18.030 57.083 1.00 143.08 ? 121 ILE C O 1 +ATOM 4750 C CB . ILE C 1 121 ? 5.973 -18.122 60.204 1.00 113.31 ? 121 ILE C CB 1 +ATOM 4751 C CG1 . ILE C 1 121 ? 5.047 -19.014 59.374 1.00 125.99 ? 121 ILE C CG1 1 +ATOM 4752 C CG2 . ILE C 1 121 ? 5.191 -17.346 61.249 1.00 105.24 ? 121 ILE C CG2 1 +ATOM 4753 C CD1 . ILE C 1 121 ? 5.467 -20.467 59.353 1.00 128.48 ? 121 ILE C CD1 1 +ATOM 4754 N N . MET C 1 122 ? 8.643 -18.325 58.327 1.00 125.05 ? 122 MET C N 1 +ATOM 4755 C CA . MET C 1 122 ? 9.209 -19.233 57.370 1.00 74.60 ? 122 MET C CA 1 +ATOM 4756 C C . MET C 1 122 ? 9.560 -20.496 58.119 1.00 52.51 ? 122 MET C C 1 +ATOM 4757 O O . MET C 1 122 ? 10.034 -20.449 59.237 1.00 45.20 ? 122 MET C O 1 +ATOM 4758 C CB . MET C 1 122 ? 10.378 -18.557 56.604 1.00 73.01 ? 122 MET C CB 1 +ATOM 4759 C CG . MET C 1 122 ? 11.503 -17.985 57.442 1.00 61.24 ? 122 MET C CG 1 +ATOM 4760 S SD . MET C 1 122 ? 12.997 -17.945 56.446 1.00 84.11 ? 122 MET C SD 1 +ATOM 4761 C CE . MET C 1 122 ? 14.174 -18.606 57.688 1.00 134.53 ? 122 MET C CE 1 +ATOM 4762 N N . VAL C 1 123 ? 9.393 -21.617 57.455 1.00 51.85 ? 123 VAL C N 1 +ATOM 4763 C CA . VAL C 1 123 ? 9.768 -22.898 58.032 1.00 69.62 ? 123 VAL C CA 1 +ATOM 4764 C C . VAL C 1 123 ? 10.852 -23.609 57.239 1.00 75.55 ? 123 VAL C C 1 +ATOM 4765 O O . VAL C 1 123 ? 10.765 -23.754 56.020 1.00 91.59 ? 123 VAL C O 1 +ATOM 4766 C CB . VAL C 1 123 ? 8.568 -23.843 58.088 1.00 100.91 ? 123 VAL C CB 1 +ATOM 4767 C CG1 . VAL C 1 123 ? 7.733 -23.742 56.815 1.00 117.82 ? 123 VAL C CG1 1 +ATOM 4768 C CG2 . VAL C 1 123 ? 9.007 -25.287 58.343 1.00 113.65 ? 123 VAL C CG2 1 +ATOM 4769 N N . GLU C 1 124 ? 11.899 -24.019 57.926 1.00 76.01 ? 124 GLU C N 1 +ATOM 4770 C CA . GLU C 1 124 ? 12.958 -24.778 57.289 1.00 83.64 ? 124 GLU C CA 1 +ATOM 4771 C C . GLU C 1 124 ? 13.223 -26.002 58.100 1.00 83.21 ? 124 GLU C C 1 +ATOM 4772 O O . GLU C 1 124 ? 12.792 -26.114 59.239 1.00 110.86 ? 124 GLU C O 1 +ATOM 4773 C CB . GLU C 1 124 ? 14.256 -23.954 57.116 1.00 102.35 ? 124 GLU C CB 1 +ATOM 4774 C CG . GLU C 1 124 ? 14.504 -22.852 58.137 1.00 114.46 ? 124 GLU C CG 1 +ATOM 4775 C CD . GLU C 1 124 ? 15.543 -21.854 57.660 1.00 110.18 ? 124 GLU C CD 1 +ATOM 4776 O OE1 . GLU C 1 124 ? 15.564 -21.540 56.446 1.00 122.78 ? 124 GLU C OE1 1 +ATOM 4777 O OE2 . GLU C 1 124 ? 16.308 -21.357 58.498 1.00 91.84 ? 124 GLU C OE2 1 +ATOM 4778 N N . GLY C 1 125 ? 14.040 -26.875 57.545 1.00 95.80 ? 125 GLY C N 1 +ATOM 4779 C CA . GLY C 1 125 ? 14.346 -28.131 58.193 1.00 99.17 ? 125 GLY C CA 1 +ATOM 4780 C C . GLY C 1 125 ? 15.400 -28.915 57.436 1.00 92.90 ? 125 GLY C C 1 +ATOM 4781 O O . GLY C 1 125 ? 16.165 -28.361 56.653 1.00 93.35 ? 125 GLY C O 1 +ATOM 4782 N N . SER C 1 126 ? 15.468 -30.206 57.710 1.00 80.89 ? 126 SER C N 1 +ATOM 4783 C CA . SER C 1 126 ? 16.537 -31.020 57.174 1.00 79.85 ? 126 SER C CA 1 +ATOM 4784 C C . SER C 1 126 ? 16.128 -32.458 57.244 1.00 88.81 ? 126 SER C C 1 +ATOM 4785 O O . SER C 1 126 ? 15.420 -32.863 58.164 1.00 124.95 ? 126 SER C O 1 +ATOM 4786 C CB . SER C 1 126 ? 17.818 -30.838 57.975 1.00 87.22 ? 126 SER C CB 1 +ATOM 4787 O OG . SER C 1 126 ? 17.956 -29.524 58.534 1.00 135.23 ? 126 SER C OG 1 +ATOM 4788 N N . ILE C 1 127 ? 16.581 -33.247 56.290 1.00 87.04 ? 127 ILE C N 1 +ATOM 4789 C CA . ILE C 1 127 ? 16.513 -34.683 56.453 1.00 89.01 ? 127 ILE C CA 1 +ATOM 4790 C C . ILE C 1 127 ? 17.654 -35.106 57.370 1.00 98.79 ? 127 ILE C C 1 +ATOM 4791 O O . ILE C 1 127 ? 18.807 -35.139 56.977 1.00 133.47 ? 127 ILE C O 1 +ATOM 4792 C CB . ILE C 1 127 ? 16.599 -35.437 55.124 1.00 94.45 ? 127 ILE C CB 1 +ATOM 4793 C CG1 . ILE C 1 127 ? 15.364 -35.144 54.263 1.00 88.28 ? 127 ILE C CG1 1 +ATOM 4794 C CG2 . ILE C 1 127 ? 16.731 -36.941 55.369 1.00 95.97 ? 127 ILE C CG2 1 +ATOM 4795 C CD1 . ILE C 1 127 ? 15.635 -35.198 52.764 1.00 92.17 ? 127 ILE C CD1 1 +ATOM 4796 N N . ILE C 1 128 ? 17.313 -35.368 58.621 1.00 93.62 ? 128 ILE C N 1 +ATOM 4797 C CA . ILE C 1 128 ? 18.268 -35.738 59.653 1.00 84.18 ? 128 ILE C CA 1 +ATOM 4798 C C . ILE C 1 128 ? 18.231 -37.244 59.621 1.00 72.74 ? 128 ILE C C 1 +ATOM 4799 O O . ILE C 1 128 ? 17.319 -37.907 60.098 1.00 98.88 ? 128 ILE C O 1 +ATOM 4800 C CB . ILE C 1 128 ? 17.873 -35.132 61.031 1.00 106.75 ? 128 ILE C CB 1 +ATOM 4801 C CG1 . ILE C 1 128 ? 16.410 -35.461 61.394 1.00 130.90 ? 128 ILE C CG1 1 +ATOM 4802 C CG2 . ILE C 1 128 ? 17.932 -33.610 60.976 1.00 117.63 ? 128 ILE C CG2 1 +ATOM 4803 C CD1 . ILE C 1 128 ? 16.140 -35.432 62.888 1.00 123.55 ? 128 ILE C CD1 1 +ATOM 4804 N N . GLY C 1 129 ? 19.197 -37.809 58.948 1.00 93.62 ? 129 GLY C N 1 +ATOM 4805 C CA . GLY C 1 129 ? 19.487 -39.231 59.130 1.00 129.39 ? 129 GLY C CA 1 +ATOM 4806 C C . GLY C 1 129 ? 18.704 -40.227 58.280 1.00 123.46 ? 129 GLY C C 1 +ATOM 4807 O O . GLY C 1 129 ? 17.504 -40.103 58.051 1.00 81.20 ? 129 GLY C O 1 +ATOM 4808 N N . TYR C 1 130 ? 19.459 -41.183 57.746 1.00 136.84 ? 130 TYR C N 1 +ATOM 4809 C CA . TYR C 1 130 ? 18.906 -42.394 57.151 1.00 92.90 ? 130 TYR C CA 1 +ATOM 4810 C C . TYR C 1 130 ? 19.850 -43.498 57.563 1.00 109.00 ? 130 TYR C C 1 +ATOM 4811 O O . TYR C 1 130 ? 21.002 -43.523 57.128 1.00 157.13 ? 130 TYR C O 1 +ATOM 4812 C CB . TYR C 1 130 ? 18.845 -42.276 55.622 1.00 94.82 ? 130 TYR C CB 1 +ATOM 4813 C CG . TYR C 1 130 ? 18.404 -43.515 54.901 1.00 77.56 ? 130 TYR C CG 1 +ATOM 4814 C CD1 . TYR C 1 130 ? 19.257 -44.606 54.783 1.00 79.40 ? 130 TYR C CD1 1 +ATOM 4815 C CD2 . TYR C 1 130 ? 17.180 -43.555 54.236 1.00 84.75 ? 130 TYR C CD2 1 +ATOM 4816 C CE1 . TYR C 1 130 ? 18.877 -45.734 54.066 1.00 94.37 ? 130 TYR C CE1 1 +ATOM 4817 C CE2 . TYR C 1 130 ? 16.795 -44.666 53.505 1.00 92.95 ? 130 TYR C CE2 1 +ATOM 4818 C CZ . TYR C 1 130 ? 17.635 -45.754 53.425 1.00 93.74 ? 130 TYR C CZ 1 +ATOM 4819 O OH . TYR C 1 130 ? 17.203 -46.889 52.781 1.00 78.74 ? 130 TYR C OH 1 +ATOM 4820 N N . GLU C 1 131 ? 19.421 -44.316 58.510 1.00 108.86 ? 131 GLU C N 1 +ATOM 4821 C CA . GLU C 1 131 ? 20.201 -45.500 58.896 1.00 108.28 ? 131 GLU C CA 1 +ATOM 4822 C C . GLU C 1 131 ? 19.594 -46.693 58.166 1.00 95.76 ? 131 GLU C C 1 +ATOM 4823 O O . GLU C 1 131 ? 18.408 -46.680 57.822 1.00 70.66 ? 131 GLU C O 1 +ATOM 4824 C CB . GLU C 1 131 ? 20.296 -45.724 60.433 1.00 143.64 ? 131 GLU C CB 1 +ATOM 4825 C CG . GLU C 1 131 ? 21.464 -44.908 61.135 1.00 197.43 ? 131 GLU C CG 1 +ATOM 4826 C CD . GLU C 1 131 ? 21.570 -43.442 60.652 1.00 204.30 ? 131 GLU C CD 1 +ATOM 4827 O OE1 . GLU C 1 131 ? 20.556 -42.746 60.500 1.00 227.34 ? 131 GLU C OE1 1 +ATOM 4828 O OE2 . GLU C 1 131 ? 22.676 -42.935 60.452 1.00 164.02 ? 131 GLU C OE2 1 +ATOM 4829 N N . SER C 1 132 ? 20.451 -47.620 57.744 1.00 114.94 ? 132 SER C N 1 +ATOM 4830 C CA . SER C 1 132 ? 20.029 -48.679 56.833 1.00 118.12 ? 132 SER C CA 1 +ATOM 4831 C C . SER C 1 132 ? 20.158 -50.047 57.496 1.00 148.40 ? 132 SER C C 1 +ATOM 4832 O O . SER C 1 132 ? 21.142 -50.323 58.185 1.00 157.78 ? 132 SER C O 1 +ATOM 4833 C CB . SER C 1 132 ? 20.828 -48.631 55.519 1.00 111.52 ? 132 SER C CB 1 +ATOM 4834 O OG . SER C 1 132 ? 21.682 -49.748 55.393 1.00 103.19 ? 132 SER C OG 1 +ATOM 4835 N N . ASN C 1 133 ? 19.175 -50.914 57.236 1.00 159.27 ? 133 ASN C N 1 +ATOM 4836 C CA . ASN C 1 133 ? 19.051 -52.211 57.923 1.00 140.01 ? 133 ASN C CA 1 +ATOM 4837 C C . ASN C 1 133 ? 19.158 -52.045 59.428 1.00 127.76 ? 133 ASN C C 1 +ATOM 4838 O O . ASN C 1 133 ? 20.038 -52.620 60.073 1.00 113.65 ? 133 ASN C O 1 +ATOM 4839 C CB . ASN C 1 133 ? 20.092 -53.220 57.425 1.00 142.64 ? 133 ASN C CB 1 +ATOM 4840 C CG . ASN C 1 133 ? 19.931 -53.555 55.948 1.00 146.61 ? 133 ASN C CG 1 +ATOM 4841 O OD1 . ASN C 1 133 ? 18.837 -53.472 55.383 1.00 179.74 ? 133 ASN C OD1 1 +ATOM 4842 N ND2 . ASN C 1 133 ? 21.050 -53.859 55.309 1.00 115.52 ? 133 ASN C ND2 1 +ATOM 4843 N N . VAL C 1 134 ? 18.297 -51.180 59.955 1.00 109.11 ? 134 VAL C N 1 +ATOM 4844 C CA . VAL C 1 134 ? 18.265 -50.873 61.374 1.00 102.37 ? 134 VAL C CA 1 +ATOM 4845 C C . VAL C 1 134 ? 17.780 -52.131 62.069 1.00 126.17 ? 134 VAL C C 1 +ATOM 4846 O O . VAL C 1 134 ? 18.253 -52.474 63.159 1.00 189.58 ? 134 VAL C O 1 +ATOM 4847 C CB . VAL C 1 134 ? 17.327 -49.684 61.676 1.00 105.38 ? 134 VAL C CB 1 +ATOM 4848 C CG1 . VAL C 1 134 ? 17.333 -49.330 63.152 1.00 111.71 ? 134 VAL C CG1 1 +ATOM 4849 C CG2 . VAL C 1 134 ? 17.742 -48.462 60.861 1.00 114.26 ? 134 VAL C CG2 1 +ATOM 4850 N N . LYS C 1 135 ? 16.886 -52.857 61.401 1.00 121.21 ? 135 LYS C N 1 +ATOM 4851 C CA . LYS C 1 135 ? 16.618 -54.250 61.764 1.00 112.28 ? 135 LYS C CA 1 +ATOM 4852 C C . LYS C 1 135 ? 16.553 -55.138 60.534 1.00 126.56 ? 135 LYS C C 1 +ATOM 4853 O O . LYS C 1 135 ? 16.289 -54.678 59.411 1.00 159.72 ? 135 LYS C O 1 +ATOM 4854 C CB . LYS C 1 135 ? 15.310 -54.351 62.536 1.00 116.00 ? 135 LYS C CB 1 +ATOM 4855 C CG . LYS C 1 135 ? 15.327 -53.601 63.856 1.00 141.39 ? 135 LYS C CG 1 +ATOM 4856 C CD . LYS C 1 135 ? 13.960 -53.646 64.514 1.00 179.25 ? 135 LYS C CD 1 +ATOM 4857 C CE . LYS C 1 135 ? 13.942 -52.898 65.830 1.00 186.41 ? 135 LYS C CE 1 +ATOM 4858 N NZ . LYS C 1 135 ? 12.808 -53.360 66.674 1.00 177.30 ? 135 LYS C NZ 1 +ATOM 4859 N N . SER C 1 136 ? 16.720 -56.432 60.763 1.00 134.10 ? 136 SER C N 1 +ATOM 4860 C CA . SER C 1 136 ? 16.637 -57.413 59.688 1.00 160.36 ? 136 SER C CA 1 +ATOM 4861 C C . SER C 1 136 ? 16.466 -58.820 60.236 1.00 152.64 ? 136 SER C C 1 +ATOM 4862 O O . SER C 1 136 ? 16.815 -59.095 61.384 1.00 174.74 ? 136 SER C O 1 +ATOM 4863 C CB . SER C 1 136 ? 17.878 -57.341 58.793 1.00 162.18 ? 136 SER C CB 1 +ATOM 4864 O OG . SER C 1 136 ? 18.523 -58.603 58.696 1.00 192.17 ? 136 SER C OG 1 +ATOM 4865 N N . GLY C 1 137 ? 15.923 -59.706 59.411 1.00 139.47 ? 137 GLY C N 1 +ATOM 4866 C CA . GLY C 1 137 ? 15.733 -61.095 59.815 1.00 153.11 ? 137 GLY C CA 1 +ATOM 4867 C C . GLY C 1 137 ? 15.380 -62.015 58.667 1.00 167.85 ? 137 GLY C C 1 +ATOM 4868 O O . GLY C 1 137 ? 15.182 -61.564 57.540 1.00 196.73 ? 137 GLY C O 1 +ATOM 4869 N N . GLY C 1 138 ? 15.329 -63.312 58.946 1.00 182.88 ? 138 GLY C N 1 +ATOM 4870 C CA . GLY C 1 138 ? 15.022 -64.296 57.916 1.00 190.39 ? 138 GLY C CA 1 +ATOM 4871 C C . GLY C 1 138 ? 14.702 -65.657 58.489 1.00 198.86 ? 138 GLY C C 1 +ATOM 4872 O O . GLY C 1 138 ? 15.265 -66.066 59.507 1.00 250.30 ? 138 GLY C O 1 +ATOM 4873 N N . VAL C 1 139 ? 13.774 -66.352 57.840 1.00 193.96 ? 139 VAL C N 1 +ATOM 4874 C CA . VAL C 1 139 ? 13.390 -67.711 58.227 1.00 180.29 ? 139 VAL C CA 1 +ATOM 4875 C C . VAL C 1 139 ? 13.183 -68.576 56.986 1.00 182.45 ? 139 VAL C C 1 +ATOM 4876 O O . VAL C 1 139 ? 12.420 -68.210 56.090 1.00 217.11 ? 139 VAL C O 1 +ATOM 4877 C CB . VAL C 1 139 ? 12.086 -67.730 59.047 1.00 150.32 ? 139 VAL C CB 1 +ATOM 4878 C CG1 . VAL C 1 139 ? 11.661 -69.164 59.310 1.00 133.23 ? 139 VAL C CG1 1 +ATOM 4879 C CG2 . VAL C 1 139 ? 12.254 -66.968 60.358 1.00 151.55 ? 139 VAL C CG2 1 +ATOM 4880 N N . GLY C 1 140 ? 13.866 -69.718 56.941 1.00 181.39 ? 140 GLY C N 1 +ATOM 4881 C CA . GLY C 1 140 ? 13.785 -70.619 55.798 1.00 172.69 ? 140 GLY C CA 1 +ATOM 4882 C C . GLY C 1 140 ? 13.982 -72.076 56.155 1.00 186.45 ? 140 GLY C C 1 +ATOM 4883 O O . GLY C 1 140 ? 14.777 -72.416 57.036 1.00 196.80 ? 140 GLY C O 1 +ATOM 4884 N N . ALA C 1 141 ? 13.234 -72.943 55.482 1.00 200.99 ? 141 ALA C N 1 +ATOM 4885 C CA . ALA C 1 141 ? 13.302 -74.375 55.745 1.00 183.37 ? 141 ALA C CA 1 +ATOM 4886 C C . ALA C 1 141 ? 13.125 -75.190 54.466 1.00 185.98 ? 141 ALA C C 1 +ATOM 4887 O O . ALA C 1 141 ? 12.320 -74.849 53.591 1.00 188.97 ? 141 ALA C O 1 +ATOM 4888 C CB . ALA C 1 141 ? 12.273 -74.775 56.792 1.00 146.81 ? 141 ALA C CB 1 +ATOM 4889 N N . ARG C 1 142 ? 13.930 -76.234 54.345 1.00 186.59 ? 142 ARG C N 1 +ATOM 4890 C CA . ARG C 1 142 ? 13.807 -77.147 53.236 1.00 179.97 ? 142 ARG C CA 1 +ATOM 4891 C C . ARG C 1 142 ? 13.762 -78.569 53.777 1.00 190.34 ? 142 ARG C C 1 +ATOM 4892 O O . ARG C 1 142 ? 14.399 -78.887 54.784 1.00 129.86 ? 142 ARG C O 1 +ATOM 4893 C CB . ARG C 1 142 ? 14.960 -76.975 52.243 1.00 163.56 ? 142 ARG C CB 1 +ATOM 4894 C CG . ARG C 1 142 ? 14.810 -77.864 51.021 1.00 157.56 ? 142 ARG C CG 1 +ATOM 4895 C CD . ARG C 1 142 ? 15.187 -77.141 49.759 1.00 164.02 ? 142 ARG C CD 1 +ATOM 4896 N NE . ARG C 1 142 ? 16.634 -77.043 49.735 1.00 168.17 ? 142 ARG C NE 1 +ATOM 4897 C CZ . ARG C 1 142 ? 17.293 -76.051 49.147 1.00 198.76 ? 142 ARG C CZ 1 +ATOM 4898 N NH1 . ARG C 1 142 ? 16.672 -75.161 48.367 1.00 210.05 ? 142 ARG C NH1 1 +ATOM 4899 N NH2 . ARG C 1 142 ? 18.613 -76.022 49.231 1.00 237.01 ? 142 ARG C NH2 1 +ATOM 4900 N N . TYR C 1 143 ? 12.959 -79.406 53.123 1.00 227.84 ? 143 TYR C N 1 +ATOM 4901 C CA . TYR C 1 143 ? 12.663 -80.757 53.614 1.00 205.12 ? 143 TYR C CA 1 +ATOM 4902 C C . TYR C 1 143 ? 12.849 -81.819 52.520 1.00 178.19 ? 143 TYR C C 1 +ATOM 4903 O O . TYR C 1 143 ? 11.903 -82.204 51.832 1.00 117.15 ? 143 TYR C O 1 +ATOM 4904 C CB . TYR C 1 143 ? 11.233 -80.799 54.167 1.00 178.59 ? 143 TYR C CB 1 +ATOM 4905 C CG . TYR C 1 143 ? 10.879 -82.086 54.832 1.00 168.92 ? 143 TYR C CG 1 +ATOM 4906 C CD1 . TYR C 1 143 ? 11.432 -82.422 56.060 1.00 174.67 ? 143 TYR C CD1 1 +ATOM 4907 C CD2 . TYR C 1 143 ? 10.017 -82.982 54.228 1.00 163.08 ? 143 TYR C CD2 1 +ATOM 4908 C CE1 . TYR C 1 143 ? 11.122 -83.618 56.679 1.00 170.45 ? 143 TYR C CE1 1 +ATOM 4909 C CE2 . TYR C 1 143 ? 9.691 -84.179 54.842 1.00 170.20 ? 143 TYR C CE2 1 +ATOM 4910 C CZ . TYR C 1 143 ? 10.249 -84.491 56.066 1.00 169.25 ? 143 TYR C CZ 1 +ATOM 4911 O OH . TYR C 1 143 ? 9.935 -85.679 56.683 1.00 174.97 ? 143 TYR C OH 1 +ATOM 4912 N N . GLY C 1 145 ? 13.191 -82.119 49.816 1.00 163.57 ? 145 GLY C N 1 +ATOM 4913 C CA . GLY C 1 145 ? 12.988 -81.684 48.435 1.00 174.92 ? 145 GLY C CA 1 +ATOM 4914 C C . GLY C 1 145 ? 12.247 -80.361 48.252 1.00 175.71 ? 145 GLY C C 1 +ATOM 4915 O O . GLY C 1 145 ? 12.457 -79.675 47.253 1.00 126.79 ? 145 GLY C O 1 +ATOM 4916 N N . ILE C 1 146 ? 11.431 -79.975 49.235 1.00 195.86 ? 146 ILE C N 1 +ATOM 4917 C CA . ILE C 1 146 ? 10.562 -78.791 49.125 1.00 178.69 ? 146 ILE C CA 1 +ATOM 4918 C C . ILE C 1 146 ? 11.012 -77.730 50.138 1.00 191.04 ? 146 ILE C C 1 +ATOM 4919 O O . ILE C 1 146 ? 11.333 -78.056 51.277 1.00 213.68 ? 146 ILE C O 1 +ATOM 4920 C CB . ILE C 1 146 ? 9.077 -79.149 49.385 1.00 170.86 ? 146 ILE C CB 1 +ATOM 4921 C CG1 . ILE C 1 146 ? 8.731 -80.503 48.750 1.00 169.88 ? 146 ILE C CG1 1 +ATOM 4922 C CG2 . ILE C 1 146 ? 8.154 -78.064 48.844 1.00 174.77 ? 146 ILE C CG2 1 +ATOM 4923 C CD1 . ILE C 1 146 ? 8.793 -81.672 49.712 1.00 169.02 ? 146 ILE C CD1 1 +ATOM 4924 N N . GLY C 1 147 ? 11.042 -76.461 49.736 1.00 196.20 ? 147 GLY C N 1 +ATOM 4925 C CA . GLY C 1 147 ? 11.541 -75.411 50.629 1.00 177.69 ? 147 GLY C CA 1 +ATOM 4926 C C . GLY C 1 147 ? 10.948 -74.029 50.433 1.00 164.12 ? 147 GLY C C 1 +ATOM 4927 O O . GLY C 1 147 ? 10.468 -73.683 49.355 1.00 163.90 ? 147 GLY C O 1 +ATOM 4928 N N . ALA C 1 148 ? 11.009 -73.226 51.485 1.00 164.49 ? 148 ALA C N 1 +ATOM 4929 C CA . ALA C 1 148 ? 10.639 -71.824 51.390 1.00 181.47 ? 148 ALA C CA 1 +ATOM 4930 C C . ALA C 1 148 ? 11.495 -70.985 52.333 1.00 205.75 ? 148 ALA C C 1 +ATOM 4931 O O . ALA C 1 148 ? 12.208 -71.519 53.191 1.00 185.97 ? 148 ALA C O 1 +ATOM 4932 C CB . ALA C 1 148 ? 9.154 -71.648 51.688 1.00 143.69 ? 148 ALA C CB 1 +ATOM 4933 N N . ASP C 1 149 ? 11.442 -69.671 52.147 1.00 222.44 ? 149 ASP C N 1 +ATOM 4934 C CA . ASP C 1 149 ? 12.135 -68.752 53.037 1.00 188.62 ? 149 ASP C CA 1 +ATOM 4935 C C . ASP C 1 149 ? 11.620 -67.324 52.853 1.00 164.32 ? 149 ASP C C 1 +ATOM 4936 O O . ASP C 1 149 ? 11.205 -66.937 51.758 1.00 145.90 ? 149 ASP C O 1 +ATOM 4937 C CB . ASP C 1 149 ? 13.649 -68.821 52.813 1.00 167.20 ? 149 ASP C CB 1 +ATOM 4938 C CG . ASP C 1 149 ? 14.090 -68.020 51.628 1.00 177.14 ? 149 ASP C CG 1 +ATOM 4939 O OD1 . ASP C 1 149 ? 13.864 -68.481 50.491 1.00 173.40 ? 149 ASP C OD1 1 +ATOM 4940 O OD2 . ASP C 1 149 ? 14.662 -66.930 51.832 1.00 193.33 ? 149 ASP C OD2 1 +ATOM 4941 N N . THR C 1 150 ? 11.608 -66.560 53.937 1.00 146.88 ? 150 THR C N 1 +ATOM 4942 C CA . THR C 1 150 ? 11.456 -65.118 53.825 1.00 152.17 ? 150 THR C CA 1 +ATOM 4943 C C . THR C 1 150 ? 12.666 -64.422 54.438 1.00 158.20 ? 150 THR C C 1 +ATOM 4944 O O . THR C 1 150 ? 13.329 -64.970 55.317 1.00 128.36 ? 150 THR C O 1 +ATOM 4945 C CB . THR C 1 150 ? 10.157 -64.611 54.490 1.00 137.70 ? 150 THR C CB 1 +ATOM 4946 O OG1 . THR C 1 150 ? 10.150 -64.958 55.874 1.00 153.91 ? 150 THR C OG1 1 +ATOM 4947 C CG2 . THR C 1 150 ? 8.935 -65.196 53.816 1.00 130.72 ? 150 THR C CG2 1 +ATOM 4948 N N . GLN C 1 151 ? 12.939 -63.214 53.966 1.00 166.39 ? 151 GLN C N 1 +ATOM 4949 C CA . GLN C 1 151 ? 13.891 -62.337 54.643 1.00 185.48 ? 151 GLN C CA 1 +ATOM 4950 C C . GLN C 1 151 ? 13.335 -60.904 54.634 1.00 190.00 ? 151 GLN C C 1 +ATOM 4951 O O . GLN C 1 151 ? 12.568 -60.512 53.753 1.00 162.75 ? 151 GLN C O 1 +ATOM 4952 C CB . GLN C 1 151 ? 15.328 -62.442 54.077 1.00 183.51 ? 151 GLN C CB 1 +ATOM 4953 C CG . GLN C 1 151 ? 15.514 -61.840 52.707 1.00 200.69 ? 151 GLN C CG 1 +ATOM 4954 C CD . GLN C 1 151 ? 16.975 -61.519 52.406 1.00 204.36 ? 151 GLN C CD 1 +ATOM 4955 O OE1 . GLN C 1 151 ? 17.858 -62.298 52.724 1.00 177.72 ? 151 GLN C OE1 1 +ATOM 4956 N NE2 . GLN C 1 151 ? 17.228 -60.383 51.750 1.00 219.93 ? 151 GLN C NE2 1 +ATOM 4957 N N . TYR C 1 152 ? 13.619 -60.160 55.693 1.00 197.39 ? 152 TYR C N 1 +ATOM 4958 C CA . TYR C 1 152 ? 13.155 -58.779 55.780 1.00 166.17 ? 152 TYR C CA 1 +ATOM 4959 C C . TYR C 1 152 ? 14.242 -57.855 56.285 1.00 154.51 ? 152 TYR C C 1 +ATOM 4960 O O . TYR C 1 152 ? 15.061 -58.270 57.104 1.00 149.94 ? 152 TYR C O 1 +ATOM 4961 C CB . TYR C 1 152 ? 11.901 -58.677 56.653 1.00 140.27 ? 152 TYR C CB 1 +ATOM 4962 C CG . TYR C 1 152 ? 12.087 -58.090 58.041 1.00 108.15 ? 152 TYR C CG 1 +ATOM 4963 C CD1 . TYR C 1 152 ? 12.860 -58.734 58.999 1.00 97.45 ? 152 TYR C CD1 1 +ATOM 4964 C CD2 . TYR C 1 152 ? 11.378 -56.966 58.428 1.00 113.07 ? 152 TYR C CD2 1 +ATOM 4965 C CE1 . TYR C 1 152 ? 12.979 -58.234 60.288 1.00 96.30 ? 152 TYR C CE1 1 +ATOM 4966 C CE2 . TYR C 1 152 ? 11.444 -56.482 59.725 1.00 114.73 ? 152 TYR C CE2 1 +ATOM 4967 C CZ . TYR C 1 152 ? 12.244 -57.119 60.651 1.00 108.50 ? 152 TYR C CZ 1 +ATOM 4968 O OH . TYR C 1 152 ? 12.306 -56.640 61.936 1.00 96.93 ? 152 TYR C OH 1 +ATOM 4969 N N . GLN C 1 153 ? 14.245 -56.622 55.782 1.00 129.51 ? 153 GLN C N 1 +ATOM 4970 C CA . GLN C 1 153 ? 15.095 -55.568 56.345 1.00 128.52 ? 153 GLN C CA 1 +ATOM 4971 C C . GLN C 1 153 ? 14.247 -54.324 56.533 1.00 109.84 ? 153 GLN C C 1 +ATOM 4972 O O . GLN C 1 153 ? 13.282 -54.096 55.794 1.00 92.81 ? 153 GLN C O 1 +ATOM 4973 C CB . GLN C 1 153 ? 16.303 -55.285 55.414 1.00 133.86 ? 153 GLN C CB 1 +ATOM 4974 C CG . GLN C 1 153 ? 16.165 -54.052 54.501 1.00 126.68 ? 153 GLN C CG 1 +ATOM 4975 C CD . GLN C 1 153 ? 17.371 -53.804 53.590 1.00 95.48 ? 153 GLN C CD 1 +ATOM 4976 O OE1 . GLN C 1 153 ? 18.157 -54.708 53.429 1.00 113.23 ? 153 GLN C OE1 1 +ATOM 4977 N NE2 . GLN C 1 153 ? 17.369 -52.701 52.815 1.00 68.82 ? 153 GLN C NE2 1 +ATOM 4978 N N . LEU C 1 154 ? 14.656 -53.478 57.472 1.00 102.54 ? 154 LEU C N 1 +ATOM 4979 C CA . LEU C 1 154 ? 14.057 -52.156 57.573 1.00 116.89 ? 154 LEU C CA 1 +ATOM 4980 C C . LEU C 1 154 ? 15.051 -51.060 57.946 1.00 104.09 ? 154 LEU C C 1 +ATOM 4981 O O . LEU C 1 154 ? 15.970 -51.276 58.765 1.00 114.80 ? 154 LEU C O 1 +ATOM 4982 C CB . LEU C 1 154 ? 12.887 -52.183 58.555 1.00 117.66 ? 154 LEU C CB 1 +ATOM 4983 C CG . LEU C 1 154 ? 13.250 -52.319 60.034 1.00 134.50 ? 154 LEU C CG 1 +ATOM 4984 C CD1 . LEU C 1 154 ? 13.331 -50.962 60.722 1.00 121.23 ? 154 LEU C CD1 1 +ATOM 4985 C CD2 . LEU C 1 154 ? 12.241 -53.231 60.718 1.00 161.11 ? 154 LEU C CD2 1 +ATOM 4986 N N . ASP C 1 155 ? 14.760 -49.866 57.416 1.00 76.55 ? 155 ASP C N 1 +ATOM 4987 C CA . ASP C 1 155 ? 15.637 -48.708 57.465 1.00 79.46 ? 155 ASP C CA 1 +ATOM 4988 C C . ASP C 1 155 ? 14.908 -47.546 58.131 1.00 82.71 ? 155 ASP C C 1 +ATOM 4989 O O . ASP C 1 155 ? 13.696 -47.578 58.264 1.00 82.71 ? 155 ASP C O 1 +ATOM 4990 C CB . ASP C 1 155 ? 16.023 -48.302 56.055 1.00 78.19 ? 155 ASP C CB 1 +ATOM 4991 C CG . ASP C 1 155 ? 16.453 -49.488 55.215 1.00 89.81 ? 155 ASP C CG 1 +ATOM 4992 O OD1 . ASP C 1 155 ? 15.573 -50.199 54.693 1.00 80.93 ? 155 ASP C OD1 1 +ATOM 4993 O OD2 . ASP C 1 155 ? 17.681 -49.679 55.021 1.00 112.43 ? 155 ASP C OD2 1 +ATOM 4994 N N . GLN C 1 156 ? 15.658 -46.550 58.603 1.00 93.33 ? 156 GLN C N 1 +ATOM 4995 C CA . GLN C 1 156 ? 15.056 -45.408 59.296 1.00 92.15 ? 156 GLN C CA 1 +ATOM 4996 C C . GLN C 1 156 ? 15.305 -44.109 58.527 1.00 98.19 ? 156 GLN C C 1 +ATOM 4997 O O . GLN C 1 156 ? 16.241 -44.014 57.754 1.00 79.67 ? 156 GLN C O 1 +ATOM 4998 C CB . GLN C 1 156 ? 15.595 -45.292 60.723 1.00 93.23 ? 156 GLN C CB 1 +ATOM 4999 C CG . GLN C 1 156 ? 14.836 -44.311 61.596 1.00 90.20 ? 156 GLN C CG 1 +ATOM 5000 C CD . GLN C 1 156 ? 15.064 -44.556 63.080 1.00 103.32 ? 156 GLN C CD 1 +ATOM 5001 O OE1 . GLN C 1 156 ? 15.931 -45.351 63.482 1.00 85.52 ? 156 GLN C OE1 1 +ATOM 5002 N NE2 . GLN C 1 156 ? 14.294 -43.854 63.911 1.00 112.01 ? 156 GLN C NE2 1 +ATOM 5003 N N . ILE C 1 157 ? 14.433 -43.129 58.735 1.00 101.52 ? 157 ILE C N 1 +ATOM 5004 C CA . ILE C 1 157 ? 14.579 -41.812 58.123 1.00 79.62 ? 157 ILE C CA 1 +ATOM 5005 C C . ILE C 1 157 ? 13.902 -40.777 59.023 1.00 67.11 ? 157 ILE C C 1 +ATOM 5006 O O . ILE C 1 157 ? 12.878 -41.066 59.664 1.00 65.91 ? 157 ILE C O 1 +ATOM 5007 C CB . ILE C 1 157 ? 13.955 -41.785 56.726 1.00 73.00 ? 157 ILE C CB 1 +ATOM 5008 C CG1 . ILE C 1 157 ? 14.578 -40.692 55.886 1.00 64.83 ? 157 ILE C CG1 1 +ATOM 5009 C CG2 . ILE C 1 157 ? 12.441 -41.578 56.826 1.00 86.85 ? 157 ILE C CG2 1 +ATOM 5010 C CD1 . ILE C 1 157 ? 14.138 -40.708 54.434 1.00 78.95 ? 157 ILE C CD1 1 +ATOM 5011 N N . ALA C 1 158 ? 14.548 -39.643 59.215 1.00 64.12 ? 158 ALA C N 1 +ATOM 5012 C CA . ALA C 1 158 ? 14.036 -38.677 60.165 1.00 71.77 ? 158 ALA C CA 1 +ATOM 5013 C C . ALA C 1 158 ? 14.089 -37.332 59.548 1.00 73.61 ? 158 ALA C C 1 +ATOM 5014 O O . ALA C 1 158 ? 14.947 -37.043 58.710 1.00 131.44 ? 158 ALA C O 1 +ATOM 5015 C CB . ALA C 1 158 ? 14.801 -38.710 61.500 1.00 81.11 ? 158 ALA C CB 1 +ATOM 5016 N N . VAL C 1 159 ? 13.169 -36.490 59.971 1.00 79.68 ? 159 VAL C N 1 +ATOM 5017 C CA . VAL C 1 159 ? 13.041 -35.169 59.400 1.00 122.01 ? 159 VAL C CA 1 +ATOM 5018 C C . VAL C 1 159 ? 12.828 -34.132 60.498 1.00 152.28 ? 159 VAL C C 1 +ATOM 5019 O O . VAL C 1 159 ? 11.949 -34.270 61.347 1.00 205.52 ? 159 VAL C O 1 +ATOM 5020 C CB . VAL C 1 159 ? 11.892 -35.134 58.372 1.00 109.65 ? 159 VAL C CB 1 +ATOM 5021 C CG1 . VAL C 1 159 ? 11.418 -33.713 58.118 1.00 95.46 ? 159 VAL C CG1 1 +ATOM 5022 C CG2 . VAL C 1 159 ? 12.339 -35.776 57.069 1.00 120.35 ? 159 VAL C CG2 1 +ATOM 5023 N N . ASN C 1 160 ? 13.630 -33.073 60.453 1.00 138.97 ? 160 ASN C N 1 +ATOM 5024 C CA . ASN C 1 160 ? 13.386 -31.883 61.243 1.00 120.33 ? 160 ASN C CA 1 +ATOM 5025 C C . ASN C 1 160 ? 12.609 -30.872 60.386 1.00 90.06 ? 160 ASN C C 1 +ATOM 5026 O O . ASN C 1 160 ? 12.997 -30.579 59.257 1.00 84.56 ? 160 ASN C O 1 +ATOM 5027 C CB . ASN C 1 160 ? 14.728 -31.305 61.702 1.00 123.86 ? 160 ASN C CB 1 +ATOM 5028 C CG . ASN C 1 160 ? 14.596 -30.004 62.499 1.00 135.35 ? 160 ASN C CG 1 +ATOM 5029 O OD1 . ASN C 1 160 ? 13.906 -29.061 62.103 1.00 92.98 ? 160 ASN C OD1 1 +ATOM 5030 N ND2 . ASN C 1 160 ? 15.346 -29.918 63.587 1.00 151.53 ? 160 ASN C ND2 1 +ATOM 5031 N N . LEU C 1 161 ? 11.508 -30.347 60.931 1.00 77.83 ? 161 LEU C N 1 +ATOM 5032 C CA . LEU C 1 161 ? 10.902 -29.091 60.448 1.00 71.51 ? 161 LEU C CA 1 +ATOM 5033 C C . LEU C 1 161 ? 10.761 -28.072 61.556 1.00 65.24 ? 161 LEU C C 1 +ATOM 5034 O O . LEU C 1 161 ? 10.660 -28.420 62.728 1.00 104.82 ? 161 LEU C O 1 +ATOM 5035 C CB . LEU C 1 161 ? 9.529 -29.345 59.900 1.00 62.58 ? 161 LEU C CB 1 +ATOM 5036 C CG . LEU C 1 161 ? 9.477 -30.252 58.686 1.00 86.76 ? 161 LEU C CG 1 +ATOM 5037 C CD1 . LEU C 1 161 ? 8.034 -30.584 58.363 1.00 84.65 ? 161 LEU C CD1 1 +ATOM 5038 C CD2 . LEU C 1 161 ? 10.170 -29.581 57.502 1.00 104.79 ? 161 LEU C CD2 1 +ATOM 5039 N N . ARG C 1 162 ? 10.942 -26.812 61.230 1.00 67.21 ? 162 ARG C N 1 +ATOM 5040 C CA . ARG C 1 162 ? 10.931 -25.802 62.278 1.00 79.02 ? 162 ARG C CA 1 +ATOM 5041 C C . ARG C 1 162 ? 10.467 -24.435 61.785 1.00 96.77 ? 162 ARG C C 1 +ATOM 5042 O O . ARG C 1 162 ? 10.952 -23.917 60.776 1.00 120.33 ? 162 ARG C O 1 +ATOM 5043 C CB . ARG C 1 162 ? 12.284 -25.709 63.020 1.00 77.79 ? 162 ARG C CB 1 +ATOM 5044 C CG . ARG C 1 162 ? 13.488 -25.274 62.205 1.00 104.09 ? 162 ARG C CG 1 +ATOM 5045 C CD . ARG C 1 162 ? 14.610 -24.831 63.132 1.00 131.39 ? 162 ARG C CD 1 +ATOM 5046 N NE . ARG C 1 162 ? 15.737 -24.215 62.423 1.00 153.33 ? 162 ARG C NE 1 +ATOM 5047 C CZ . ARG C 1 162 ? 16.722 -24.880 61.829 1.00 133.24 ? 162 ARG C CZ 1 +ATOM 5048 N NH1 . ARG C 1 162 ? 16.689 -26.201 61.751 1.00 115.05 ? 162 ARG C NH1 1 +ATOM 5049 N NH2 . ARG C 1 162 ? 17.729 -24.206 61.285 1.00 137.78 ? 162 ARG C NH2 1 +ATOM 5050 N N . VAL C 1 163 ? 9.537 -23.852 62.541 1.00 114.70 ? 163 VAL C N 1 +ATOM 5051 C CA . VAL C 1 163 ? 8.969 -22.530 62.250 1.00 127.21 ? 163 VAL C CA 1 +ATOM 5052 C C . VAL C 1 163 ? 9.826 -21.449 62.862 1.00 128.67 ? 163 VAL C C 1 +ATOM 5053 O O . VAL C 1 163 ? 10.010 -21.425 64.080 1.00 191.42 ? 163 VAL C O 1 +ATOM 5054 C CB . VAL C 1 163 ? 7.566 -22.349 62.859 1.00 108.65 ? 163 VAL C CB 1 +ATOM 5055 C CG1 . VAL C 1 163 ? 7.047 -20.945 62.544 1.00 81.89 ? 163 VAL C CG1 1 +ATOM 5056 C CG2 . VAL C 1 163 ? 6.628 -23.449 62.364 1.00 116.00 ? 163 VAL C CG2 1 +ATOM 5057 N N . VAL C 1 164 ? 10.293 -20.537 62.017 1.00 90.28 ? 164 VAL C N 1 +ATOM 5058 C CA . VAL C 1 164 ? 11.134 -19.421 62.445 1.00 62.18 ? 164 VAL C CA 1 +ATOM 5059 C C . VAL C 1 164 ? 10.394 -18.137 62.230 1.00 61.64 ? 164 VAL C C 1 +ATOM 5060 O O . VAL C 1 164 ? 9.717 -17.971 61.184 1.00 90.66 ? 164 VAL C O 1 +ATOM 5061 C CB . VAL C 1 164 ? 12.408 -19.333 61.622 1.00 56.52 ? 164 VAL C CB 1 +ATOM 5062 C CG1 . VAL C 1 164 ? 13.218 -18.134 62.041 1.00 53.04 ? 164 VAL C CG1 1 +ATOM 5063 C CG2 . VAL C 1 164 ? 13.208 -20.595 61.780 1.00 58.07 ? 164 VAL C CG2 1 +ATOM 5064 N N . ASN C 1 165 ? 10.459 -17.263 63.227 1.00 48.84 ? 165 ASN C N 1 +ATOM 5065 C CA . ASN C 1 165 ? 9.725 -16.021 63.137 1.00 67.05 ? 165 ASN C CA 1 +ATOM 5066 C C . ASN C 1 165 ? 10.557 -14.991 62.430 1.00 79.49 ? 165 ASN C C 1 +ATOM 5067 O O . ASN C 1 165 ? 11.657 -14.655 62.908 1.00 109.77 ? 165 ASN C O 1 +ATOM 5068 C CB . ASN C 1 165 ? 9.345 -15.499 64.509 1.00 76.12 ? 165 ASN C CB 1 +ATOM 5069 C CG . ASN C 1 165 ? 8.434 -14.274 64.420 1.00 98.62 ? 165 ASN C CG 1 +ATOM 5070 O OD1 . ASN C 1 165 ? 7.925 -13.927 63.350 1.00 51.42 ? 165 ASN C OD1 1 +ATOM 5071 N ND2 . ASN C 1 165 ? 8.255 -13.595 65.544 1.00 125.55 ? 165 ASN C ND2 1 +ATOM 5072 N N . VAL C 1 166 ? 10.050 -14.478 61.302 1.00 86.71 ? 166 VAL C N 1 +ATOM 5073 C CA . VAL C 1 166 ? 10.808 -13.533 60.465 1.00 106.07 ? 166 VAL C CA 1 +ATOM 5074 C C . VAL C 1 166 ? 11.112 -12.253 61.226 1.00 107.58 ? 166 VAL C C 1 +ATOM 5075 O O . VAL C 1 166 ? 12.219 -11.736 61.149 1.00 85.03 ? 166 VAL C O 1 +ATOM 5076 C CB . VAL C 1 166 ? 10.034 -13.166 59.191 1.00 100.73 ? 166 VAL C CB 1 +ATOM 5077 C CG1 . VAL C 1 166 ? 10.458 -11.798 58.642 1.00 80.19 ? 166 VAL C CG1 1 +ATOM 5078 C CG2 . VAL C 1 166 ? 10.187 -14.282 58.161 1.00 114.79 ? 166 VAL C CG2 1 +ATOM 5079 N N . SER C 1 167 ? 10.158 -11.840 62.053 1.00 105.72 ? 167 SER C N 1 +ATOM 5080 C CA . SER C 1 167 ? 10.249 -10.576 62.750 1.00 106.53 ? 167 SER C CA 1 +ATOM 5081 C C . SER C 1 167 ? 11.282 -10.571 63.886 1.00 112.39 ? 167 SER C C 1 +ATOM 5082 O O . SER C 1 167 ? 11.656 -9.504 64.365 1.00 95.40 ? 167 SER C O 1 +ATOM 5083 C CB . SER C 1 167 ? 8.876 -10.202 63.283 1.00 128.89 ? 167 SER C CB 1 +ATOM 5084 O OG . SER C 1 167 ? 7.878 -10.424 62.294 1.00 179.01 ? 167 SER C OG 1 +ATOM 5085 N N . THR C 1 168 ? 11.786 -11.748 64.275 1.00 123.95 ? 168 THR C N 1 +ATOM 5086 C CA . THR C 1 168 ? 12.752 -11.850 65.380 1.00 104.91 ? 168 THR C CA 1 +ATOM 5087 C C . THR C 1 168 ? 13.917 -12.817 65.135 1.00 74.51 ? 168 THR C C 1 +ATOM 5088 O O . THR C 1 168 ? 15.017 -12.644 65.651 1.00 68.25 ? 168 THR C O 1 +ATOM 5089 C CB . THR C 1 168 ? 12.040 -12.271 66.678 1.00 127.51 ? 168 THR C CB 1 +ATOM 5090 O OG1 . THR C 1 168 ? 11.259 -13.452 66.442 1.00 122.48 ? 168 THR C OG1 1 +ATOM 5091 C CG2 . THR C 1 168 ? 11.131 -11.142 67.191 1.00 141.74 ? 168 THR C CG2 1 +ATOM 5092 N N . GLY C 1 169 ? 13.646 -13.894 64.434 1.00 65.91 ? 169 GLY C N 1 +ATOM 5093 C CA . GLY C 1 169 ? 14.614 -14.952 64.353 1.00 84.97 ? 169 GLY C CA 1 +ATOM 5094 C C . GLY C 1 169 ? 14.418 -16.005 65.425 1.00 109.74 ? 169 GLY C C 1 +ATOM 5095 O O . GLY C 1 169 ? 15.023 -17.084 65.363 1.00 125.47 ? 169 GLY C O 1 +ATOM 5096 N N . GLU C 1 170 ? 13.546 -15.731 66.394 1.00 115.57 ? 170 GLU C N 1 +ATOM 5097 C CA . GLU C 1 170 ? 13.112 -16.766 67.335 1.00 137.67 ? 170 GLU C CA 1 +ATOM 5098 C C . GLU C 1 170 ? 12.562 -17.936 66.539 1.00 130.08 ? 170 GLU C C 1 +ATOM 5099 O O . GLU C 1 170 ? 11.718 -17.765 65.677 1.00 106.90 ? 170 GLU C O 1 +ATOM 5100 C CB . GLU C 1 170 ? 12.019 -16.252 68.300 1.00 158.40 ? 170 GLU C CB 1 +ATOM 5101 C CG . GLU C 1 170 ? 12.541 -15.374 69.435 1.00 167.95 ? 170 GLU C CG 1 +ATOM 5102 C CD . GLU C 1 170 ? 11.613 -14.231 69.820 1.00 163.30 ? 170 GLU C CD 1 +ATOM 5103 O OE1 . GLU C 1 170 ? 10.646 -13.962 69.071 1.00 149.55 ? 170 GLU C OE1 1 +ATOM 5104 O OE2 . GLU C 1 170 ? 11.906 -13.536 70.822 1.00 150.53 ? 170 GLU C OE2 1 +ATOM 5105 N N . ILE C 1 171 ? 13.056 -19.135 66.815 1.00 116.56 ? 171 ILE C N 1 +ATOM 5106 C CA . ILE C 1 171 ? 12.367 -20.331 66.358 1.00 129.16 ? 171 ILE C CA 1 +ATOM 5107 C C . ILE C 1 171 ? 11.081 -20.517 67.167 1.00 132.94 ? 171 ILE C C 1 +ATOM 5108 O O . ILE C 1 171 ? 11.128 -20.497 68.389 1.00 189.36 ? 171 ILE C O 1 +ATOM 5109 C CB . ILE C 1 171 ? 13.259 -21.562 66.511 1.00 119.03 ? 171 ILE C CB 1 +ATOM 5110 C CG1 . ILE C 1 171 ? 14.401 -21.476 65.503 1.00 143.67 ? 171 ILE C CG1 1 +ATOM 5111 C CG2 . ILE C 1 171 ? 12.433 -22.824 66.312 1.00 126.02 ? 171 ILE C CG2 1 +ATOM 5112 C CD1 . ILE C 1 171 ? 15.538 -22.419 65.808 1.00 159.70 ? 171 ILE C CD1 1 +ATOM 5113 N N . LEU C 1 172 ? 9.939 -20.614 66.493 1.00 124.32 ? 172 LEU C N 1 +ATOM 5114 C CA . LEU C 1 172 ? 8.657 -20.684 67.189 1.00 105.31 ? 172 LEU C CA 1 +ATOM 5115 C C . LEU C 1 172 ? 8.218 -22.130 67.406 1.00 121.73 ? 172 LEU C C 1 +ATOM 5116 O O . LEU C 1 172 ? 7.273 -22.416 68.174 1.00 150.75 ? 172 LEU C O 1 +ATOM 5117 C CB . LEU C 1 172 ? 7.556 -19.915 66.440 1.00 83.13 ? 172 LEU C CB 1 +ATOM 5118 C CG . LEU C 1 172 ? 7.327 -18.420 66.728 1.00 78.75 ? 172 LEU C CG 1 +ATOM 5119 C CD1 . LEU C 1 172 ? 8.621 -17.820 67.233 1.00 74.75 ? 172 LEU C CD1 1 +ATOM 5120 C CD2 . LEU C 1 172 ? 6.688 -17.579 65.631 1.00 72.02 ? 172 LEU C CD2 1 +ATOM 5121 N N . SER C 1 173 ? 8.903 -23.046 66.736 1.00 108.46 ? 173 SER C N 1 +ATOM 5122 C CA . SER C 1 173 ? 8.602 -24.452 66.881 1.00 129.73 ? 173 SER C CA 1 +ATOM 5123 C C . SER C 1 173 ? 9.659 -25.293 66.185 1.00 130.72 ? 173 SER C C 1 +ATOM 5124 O O . SER C 1 173 ? 9.942 -25.097 65.012 1.00 146.87 ? 173 SER C O 1 +ATOM 5125 C CB . SER C 1 173 ? 7.219 -24.768 66.280 1.00 164.31 ? 173 SER C CB 1 +ATOM 5126 O OG . SER C 1 173 ? 7.041 -26.169 66.094 1.00 208.19 ? 173 SER C OG 1 +ATOM 5127 N N . SER C 1 174 ? 10.138 -26.328 66.866 1.00 155.60 ? 174 SER C N 1 +ATOM 5128 C CA . SER C 1 174 ? 10.930 -27.392 66.219 1.00 155.29 ? 174 SER C CA 1 +ATOM 5129 C C . SER C 1 174 ? 10.295 -28.758 66.449 1.00 144.46 ? 174 SER C C 1 +ATOM 5130 O O . SER C 1 174 ? 9.809 -29.051 67.539 1.00 167.48 ? 174 SER C O 1 +ATOM 5131 C CB . SER C 1 174 ? 12.357 -27.418 66.771 1.00 155.48 ? 174 SER C CB 1 +ATOM 5132 O OG . SER C 1 174 ? 13.214 -28.251 66.006 1.00 134.48 ? 174 SER C OG 1 +ATOM 5133 N N . VAL C 1 175 ? 10.242 -29.565 65.395 1.00 138.36 ? 175 VAL C N 1 +ATOM 5134 C CA . VAL C 1 175 ? 9.653 -30.901 65.472 1.00 131.39 ? 175 VAL C CA 1 +ATOM 5135 C C . VAL C 1 175 ? 10.528 -31.921 64.767 1.00 135.90 ? 175 VAL C C 1 +ATOM 5136 O O . VAL C 1 175 ? 11.105 -31.633 63.707 1.00 250.99 ? 175 VAL C O 1 +ATOM 5137 C CB . VAL C 1 175 ? 8.218 -30.948 64.877 1.00 118.05 ? 175 VAL C CB 1 +ATOM 5138 C CG1 . VAL C 1 175 ? 7.284 -30.059 65.676 1.00 129.59 ? 175 VAL C CG1 1 +ATOM 5139 C CG2 . VAL C 1 175 ? 8.196 -30.509 63.429 1.00 124.23 ? 175 VAL C CG2 1 +ATOM 5140 N N . ASN C 1 176 ? 10.557 -33.129 65.312 1.00 113.58 ? 176 ASN C N 1 +ATOM 5141 C CA . ASN C 1 176 ? 11.441 -34.177 64.824 1.00 133.03 ? 176 ASN C CA 1 +ATOM 5142 C C . ASN C 1 176 ? 10.665 -35.452 64.511 1.00 116.77 ? 176 ASN C C 1 +ATOM 5143 O O . ASN C 1 176 ? 10.509 -36.298 65.397 1.00 188.97 ? 176 ASN C O 1 +ATOM 5144 C CB . ASN C 1 176 ? 12.511 -34.448 65.898 1.00 146.61 ? 176 ASN C CB 1 +ATOM 5145 C CG . ASN C 1 176 ? 13.841 -33.758 65.615 1.00 141.12 ? 176 ASN C CG 1 +ATOM 5146 O OD1 . ASN C 1 176 ? 14.882 -33.995 66.296 1.00 130.52 ? 176 ASN C OD1 1 +ATOM 5147 N ND2 . ASN C 1 176 ? 13.799 -32.840 64.665 1.00 125.33 ? 176 ASN C ND2 1 +ATOM 5148 N N . THR C 1 177 ? 10.269 -35.650 63.252 1.00 83.78 ? 177 THR C N 1 +ATOM 5149 C CA . THR C 1 177 ? 9.534 -36.862 62.867 1.00 86.21 ? 177 THR C CA 1 +ATOM 5150 C C . THR C 1 177 ? 10.436 -37.969 62.310 1.00 79.25 ? 177 THR C C 1 +ATOM 5151 O O . THR C 1 177 ? 11.561 -37.714 61.896 1.00 96.67 ? 177 THR C O 1 +ATOM 5152 C CB . THR C 1 177 ? 8.439 -36.556 61.841 1.00 85.72 ? 177 THR C CB 1 +ATOM 5153 O OG1 . THR C 1 177 ? 9.040 -36.239 60.591 1.00 103.65 ? 177 THR C OG1 1 +ATOM 5154 C CG2 . THR C 1 177 ? 7.586 -35.381 62.305 1.00 86.69 ? 177 THR C CG2 1 +ATOM 5155 N N . SER C 1 178 ? 9.942 -39.202 62.342 1.00 73.93 ? 178 SER C N 1 +ATOM 5156 C CA . SER C 1 178 ? 10.724 -40.367 61.927 1.00 85.30 ? 178 SER C CA 1 +ATOM 5157 C C . SER C 1 178 ? 9.830 -41.419 61.273 1.00 98.75 ? 178 SER C C 1 +ATOM 5158 O O . SER C 1 178 ? 8.633 -41.522 61.572 1.00 116.22 ? 178 SER C O 1 +ATOM 5159 C CB . SER C 1 178 ? 11.465 -40.995 63.108 1.00 77.07 ? 178 SER C CB 1 +ATOM 5160 O OG . SER C 1 178 ? 11.956 -42.298 62.778 1.00 98.83 ? 178 SER C OG 1 +ATOM 5161 N N . LYS C 1 179 ? 10.422 -42.232 60.405 1.00 89.98 ? 179 LYS C N 1 +ATOM 5162 C CA . LYS C 1 179 ? 9.638 -43.183 59.645 1.00 99.12 ? 179 LYS C CA 1 +ATOM 5163 C C . LYS C 1 179 ? 10.505 -44.353 59.202 1.00 102.38 ? 179 LYS C C 1 +ATOM 5164 O O . LYS C 1 179 ? 11.692 -44.206 58.913 1.00 94.69 ? 179 LYS C O 1 +ATOM 5165 C CB . LYS C 1 179 ? 9.013 -42.480 58.444 1.00 106.10 ? 179 LYS C CB 1 +ATOM 5166 C CG . LYS C 1 179 ? 7.621 -42.963 58.072 1.00 114.55 ? 179 LYS C CG 1 +ATOM 5167 C CD . LYS C 1 179 ? 7.682 -44.060 57.025 1.00 138.87 ? 179 LYS C CD 1 +ATOM 5168 C CE . LYS C 1 179 ? 6.279 -44.727 57.043 1.00 155.89 ? 179 LYS C CE 1 +ATOM 5169 N NZ . LYS C 1 179 ? 5.413 -44.073 56.030 1.00 172.03 ? 179 LYS C NZ 1 +ATOM 5170 N N . THR C 1 180 ? 9.892 -45.528 59.167 1.00 129.63 ? 180 THR C N 1 +ATOM 5171 C CA . THR C 1 180 ? 10.617 -46.754 58.882 1.00 148.75 ? 180 THR C CA 1 +ATOM 5172 C C . THR C 1 180 ? 10.279 -47.267 57.479 1.00 153.35 ? 180 THR C C 1 +ATOM 5173 O O . THR C 1 180 ? 9.111 -47.340 57.088 1.00 134.23 ? 180 THR C O 1 +ATOM 5174 C CB . THR C 1 180 ? 10.353 -47.850 59.948 1.00 145.91 ? 180 THR C CB 1 +ATOM 5175 O OG1 . THR C 1 180 ? 10.596 -49.140 59.381 1.00 150.84 ? 180 THR C OG1 1 +ATOM 5176 C CG2 . THR C 1 180 ? 8.925 -47.770 60.481 1.00 118.27 ? 180 THR C CG2 1 +ATOM 5177 N N . ILE C 1 181 ? 11.320 -47.613 56.727 1.00 162.45 ? 181 ILE C N 1 +ATOM 5178 C CA . ILE C 1 181 ? 11.153 -48.161 55.384 1.00 161.99 ? 181 ILE C CA 1 +ATOM 5179 C C . ILE C 1 181 ? 11.255 -49.689 55.421 1.00 127.65 ? 181 ILE C C 1 +ATOM 5180 O O . ILE C 1 181 ? 12.323 -50.241 55.737 1.00 135.86 ? 181 ILE C O 1 +ATOM 5181 C CB . ILE C 1 181 ? 12.201 -47.565 54.404 1.00 163.63 ? 181 ILE C CB 1 +ATOM 5182 C CG1 . ILE C 1 181 ? 12.176 -46.036 54.469 1.00 165.64 ? 181 ILE C CG1 1 +ATOM 5183 C CG2 . ILE C 1 181 ? 11.940 -48.003 52.966 1.00 160.94 ? 181 ILE C CG2 1 +ATOM 5184 C CD1 . ILE C 1 181 ? 13.485 -45.423 54.910 1.00 153.05 ? 181 ILE C CD1 1 +ATOM 5185 N N . LEU C 1 182 ? 10.156 -50.356 55.073 1.00 84.55 ? 182 LEU C N 1 +ATOM 5186 C CA . LEU C 1 182 ? 10.110 -51.821 55.045 1.00 111.55 ? 182 LEU C CA 1 +ATOM 5187 C C . LEU C 1 182 ? 10.498 -52.491 53.706 1.00 122.18 ? 182 LEU C C 1 +ATOM 5188 O O . LEU C 1 182 ? 10.082 -52.052 52.630 1.00 122.05 ? 182 LEU C O 1 +ATOM 5189 C CB . LEU C 1 182 ? 8.709 -52.281 55.418 1.00 108.50 ? 182 LEU C CB 1 +ATOM 5190 C CG . LEU C 1 182 ? 8.487 -53.801 55.465 1.00 98.24 ? 182 LEU C CG 1 +ATOM 5191 C CD1 . LEU C 1 182 ? 9.359 -54.506 56.499 1.00 90.78 ? 182 LEU C CD1 1 +ATOM 5192 C CD2 . LEU C 1 182 ? 7.011 -54.042 55.729 1.00 96.58 ? 182 LEU C CD2 1 +ATOM 5193 N N . SER C 1 183 ? 11.230 -53.601 53.804 1.00 130.36 ? 183 SER C N 1 +ATOM 5194 C CA . SER C 1 183 ? 11.560 -54.429 52.649 1.00 140.31 ? 183 SER C CA 1 +ATOM 5195 C C . SER C 1 183 ? 11.476 -55.912 53.022 1.00 152.94 ? 183 SER C C 1 +ATOM 5196 O O . SER C 1 183 ? 11.874 -56.304 54.122 1.00 153.94 ? 183 SER C O 1 +ATOM 5197 C CB . SER C 1 183 ? 12.974 -54.105 52.155 1.00 154.08 ? 183 SER C CB 1 +ATOM 5198 O OG . SER C 1 183 ? 13.249 -52.720 52.252 1.00 149.32 ? 183 SER C OG 1 +ATOM 5199 N N . TYR C 1 184 ? 10.965 -56.735 52.109 1.00 157.29 ? 184 TYR C N 1 +ATOM 5200 C CA . TYR C 1 184 ? 10.921 -58.186 52.328 1.00 130.47 ? 184 TYR C CA 1 +ATOM 5201 C C . TYR C 1 184 ? 10.977 -59.018 51.044 1.00 132.90 ? 184 TYR C C 1 +ATOM 5202 O O . TYR C 1 184 ? 10.573 -58.571 49.957 1.00 144.85 ? 184 TYR C O 1 +ATOM 5203 C CB . TYR C 1 184 ? 9.706 -58.578 53.175 1.00 104.83 ? 184 TYR C CB 1 +ATOM 5204 C CG . TYR C 1 184 ? 8.376 -58.187 52.588 1.00 117.30 ? 184 TYR C CG 1 +ATOM 5205 C CD1 . TYR C 1 184 ? 7.719 -59.017 51.689 1.00 149.45 ? 184 TYR C CD1 1 +ATOM 5206 C CD2 . TYR C 1 184 ? 7.751 -57.001 52.953 1.00 113.33 ? 184 TYR C CD2 1 +ATOM 5207 C CE1 . TYR C 1 184 ? 6.496 -58.656 51.146 1.00 147.98 ? 184 TYR C CE1 1 +ATOM 5208 C CE2 . TYR C 1 184 ? 6.520 -56.637 52.421 1.00 111.44 ? 184 TYR C CE2 1 +ATOM 5209 C CZ . TYR C 1 184 ? 5.901 -57.460 51.514 1.00 118.51 ? 184 TYR C CZ 1 +ATOM 5210 O OH . TYR C 1 184 ? 4.696 -57.087 50.975 1.00 100.17 ? 184 TYR C OH 1 +ATOM 5211 N N . GLU C 1 185 ? 11.460 -60.247 51.204 1.00 148.47 ? 185 GLU C N 1 +ATOM 5212 C CA . GLU C 1 185 ? 11.645 -61.191 50.100 1.00 166.66 ? 185 GLU C CA 1 +ATOM 5213 C C . GLU C 1 185 ? 11.123 -62.566 50.472 1.00 171.19 ? 185 GLU C C 1 +ATOM 5214 O O . GLU C 1 185 ? 11.684 -63.238 51.331 1.00 192.82 ? 185 GLU C O 1 +ATOM 5215 C CB . GLU C 1 185 ? 13.110 -61.341 49.686 1.00 177.25 ? 185 GLU C CB 1 +ATOM 5216 C CG . GLU C 1 185 ? 13.917 -60.060 49.626 1.00 196.81 ? 185 GLU C CG 1 +ATOM 5217 C CD . GLU C 1 185 ? 15.276 -60.298 48.987 1.00 219.12 ? 185 GLU C CD 1 +ATOM 5218 O OE1 . GLU C 1 185 ? 15.605 -61.475 48.688 1.00 238.59 ? 185 GLU C OE1 1 +ATOM 5219 O OE2 . GLU C 1 185 ? 16.037 -59.324 48.842 1.00 210.59 ? 185 GLU C OE2 1 +ATOM 5220 N N . VAL C 1 186 ? 10.053 -62.976 49.802 1.00 172.50 ? 186 VAL C N 1 +ATOM 5221 C CA . VAL C 1 186 ? 9.460 -64.291 49.986 1.00 147.44 ? 186 VAL C CA 1 +ATOM 5222 C C . VAL C 1 186 ? 9.854 -65.205 48.822 1.00 148.19 ? 186 VAL C C 1 +ATOM 5223 O O . VAL C 1 186 ? 9.880 -64.773 47.674 1.00 127.04 ? 186 VAL C O 1 +ATOM 5224 C CB . VAL C 1 186 ? 7.923 -64.190 50.080 1.00 116.92 ? 186 VAL C CB 1 +ATOM 5225 C CG1 . VAL C 1 186 ? 7.338 -65.535 50.471 1.00 116.72 ? 186 VAL C CG1 1 +ATOM 5226 C CG2 . VAL C 1 186 ? 7.510 -63.112 51.075 1.00 97.14 ? 186 VAL C CG2 1 +ATOM 5227 N N . GLN C 1 187 ? 10.170 -66.459 49.134 1.00 151.21 ? 187 GLN C N 1 +ATOM 5228 C CA . GLN C 1 187 ? 10.653 -67.392 48.126 1.00 155.74 ? 187 GLN C CA 1 +ATOM 5229 C C . GLN C 1 187 ? 10.251 -68.813 48.456 1.00 144.63 ? 187 GLN C C 1 +ATOM 5230 O O . GLN C 1 187 ? 10.353 -69.239 49.603 1.00 124.95 ? 187 GLN C O 1 +ATOM 5231 C CB . GLN C 1 187 ? 12.183 -67.325 48.040 1.00 171.90 ? 187 GLN C CB 1 +ATOM 5232 C CG . GLN C 1 187 ? 12.745 -66.243 47.136 1.00 185.43 ? 187 GLN C CG 1 +ATOM 5233 C CD . GLN C 1 187 ? 14.186 -65.904 47.476 1.00 205.56 ? 187 GLN C CD 1 +ATOM 5234 O OE1 . GLN C 1 187 ? 14.980 -66.795 47.790 1.00 232.80 ? 187 GLN C OE1 1 +ATOM 5235 N NE2 . GLN C 1 187 ? 14.533 -64.614 47.423 1.00 204.42 ? 187 GLN C NE2 1 +ATOM 5236 N N . ALA C 1 188 ? 9.832 -69.551 47.435 1.00 165.19 ? 188 ALA C N 1 +ATOM 5237 C CA . ALA C 1 188 ? 9.489 -70.961 47.612 1.00 166.13 ? 188 ALA C CA 1 +ATOM 5238 C C . ALA C 1 188 ? 9.929 -71.779 46.404 1.00 169.92 ? 188 ALA C C 1 +ATOM 5239 O O . ALA C 1 188 ? 9.839 -71.312 45.275 1.00 174.73 ? 188 ALA C O 1 +ATOM 5240 C CB . ALA C 1 188 ? 7.994 -71.112 47.844 1.00 145.24 ? 188 ALA C CB 1 +ATOM 5241 N N . GLY C 1 189 ? 10.457 -72.974 46.649 1.00 179.58 ? 189 GLY C N 1 +ATOM 5242 C CA . GLY C 1 189 ? 10.982 -73.815 45.579 1.00 202.65 ? 189 GLY C CA 1 +ATOM 5243 C C . GLY C 1 189 ? 10.764 -75.292 45.824 1.00 205.82 ? 189 GLY C C 1 +ATOM 5244 O O . GLY C 1 189 ? 10.918 -75.768 46.949 1.00 226.46 ? 189 GLY C O 1 +ATOM 5245 N N . VAL C 1 190 ? 10.379 -76.011 44.775 1.00 196.35 ? 190 VAL C N 1 +ATOM 5246 C CA . VAL C 1 190 ? 10.163 -77.449 44.861 1.00 192.11 ? 190 VAL C CA 1 +ATOM 5247 C C . VAL C 1 190 ? 11.187 -78.176 43.985 1.00 201.67 ? 190 VAL C C 1 +ATOM 5248 O O . VAL C 1 190 ? 11.444 -77.770 42.849 1.00 178.28 ? 190 VAL C O 1 +ATOM 5249 C CB . VAL C 1 190 ? 8.731 -77.828 44.426 1.00 182.28 ? 190 VAL C CB 1 +ATOM 5250 C CG1 . VAL C 1 190 ? 8.443 -79.280 44.763 1.00 188.84 ? 190 VAL C CG1 1 +ATOM 5251 C CG2 . VAL C 1 190 ? 7.705 -76.906 45.081 1.00 173.06 ? 190 VAL C CG2 1 +ATOM 5252 N N . PHE C 1 191 ? 11.777 -79.246 44.519 1.00 214.44 ? 191 PHE C N 1 +ATOM 5253 C CA . PHE C 1 191 ? 12.904 -79.920 43.860 1.00 193.13 ? 191 PHE C CA 1 +ATOM 5254 C C . PHE C 1 191 ? 12.720 -81.441 43.861 1.00 147.77 ? 191 PHE C C 1 +ATOM 5255 O O . PHE C 1 191 ? 12.384 -82.018 44.893 1.00 87.17 ? 191 PHE C O 1 +ATOM 5256 C CB . PHE C 1 191 ? 14.219 -79.547 44.562 1.00 178.35 ? 191 PHE C CB 1 +ATOM 5257 C CG . PHE C 1 191 ? 15.445 -79.751 43.713 1.00 173.39 ? 191 PHE C CG 1 +ATOM 5258 C CD1 . PHE C 1 191 ? 15.902 -81.029 43.418 1.00 148.92 ? 191 PHE C CD1 1 +ATOM 5259 C CD2 . PHE C 1 191 ? 16.148 -78.663 43.215 1.00 195.57 ? 191 PHE C CD2 1 +ATOM 5260 C CE1 . PHE C 1 191 ? 17.034 -81.221 42.642 1.00 140.91 ? 191 PHE C CE1 1 +ATOM 5261 C CE2 . PHE C 1 191 ? 17.278 -78.848 42.431 1.00 197.98 ? 191 PHE C CE2 1 +ATOM 5262 C CZ . PHE C 1 191 ? 17.727 -80.129 42.153 1.00 166.95 ? 191 PHE C CZ 1 +ATOM 5263 N N . LEU C 1 200 ? 12.728 -82.656 38.320 1.00 108.11 ? 200 LEU C N 1 +ATOM 5264 C CA . LEU C 1 200 ? 11.744 -81.604 38.550 1.00 131.94 ? 200 LEU C CA 1 +ATOM 5265 C C . LEU C 1 200 ? 12.289 -80.530 39.482 1.00 177.44 ? 200 LEU C C 1 +ATOM 5266 O O . LEU C 1 200 ? 12.527 -80.794 40.666 1.00 215.67 ? 200 LEU C O 1 +ATOM 5267 C CB . LEU C 1 200 ? 10.457 -82.171 39.158 1.00 108.84 ? 200 LEU C CB 1 +ATOM 5268 C CG . LEU C 1 200 ? 9.458 -81.098 39.626 1.00 111.13 ? 200 LEU C CG 1 +ATOM 5269 C CD1 . LEU C 1 200 ? 8.350 -80.926 38.598 1.00 109.00 ? 200 LEU C CD1 1 +ATOM 5270 C CD2 . LEU C 1 200 ? 8.888 -81.369 41.015 1.00 98.55 ? 200 LEU C CD2 1 +ATOM 5271 N N . GLU C 1 201 ? 12.460 -79.317 38.950 1.00 184.02 ? 201 GLU C N 1 +ATOM 5272 C CA . GLU C 1 201 ? 12.610 -78.120 39.781 1.00 147.63 ? 201 GLU C CA 1 +ATOM 5273 C C . GLU C 1 201 ? 11.522 -77.109 39.465 1.00 140.86 ? 201 GLU C C 1 +ATOM 5274 O O . GLU C 1 201 ? 11.061 -77.029 38.327 1.00 165.02 ? 201 GLU C O 1 +ATOM 5275 C CB . GLU C 1 201 ? 13.980 -77.487 39.567 1.00 148.53 ? 201 GLU C CB 1 +ATOM 5276 C CG . GLU C 1 201 ? 14.387 -76.563 40.702 1.00 162.55 ? 201 GLU C CG 1 +ATOM 5277 C CD . GLU C 1 201 ? 15.762 -75.943 40.490 1.00 188.93 ? 201 GLU C CD 1 +ATOM 5278 O OE1 . GLU C 1 201 ? 16.732 -76.683 40.231 1.00 222.23 ? 201 GLU C OE1 1 +ATOM 5279 O OE2 . GLU C 1 201 ? 15.895 -74.718 40.632 1.00 181.16 ? 201 GLU C OE2 1 +ATOM 5280 N N . GLY C 1 202 ? 11.110 -76.343 40.470 1.00 142.44 ? 202 GLY C N 1 +ATOM 5281 C CA . GLY C 1 202 ? 10.164 -75.243 40.278 1.00 155.81 ? 202 GLY C CA 1 +ATOM 5282 C C . GLY C 1 202 ? 10.301 -74.185 41.365 1.00 152.27 ? 202 GLY C C 1 +ATOM 5283 O O . GLY C 1 202 ? 10.267 -74.508 42.544 1.00 138.44 ? 202 GLY C O 1 +ATOM 5284 N N . GLU C 1 203 ? 10.449 -72.921 40.970 1.00 148.30 ? 203 GLU C N 1 +ATOM 5285 C CA . GLU C 1 203 ? 10.645 -71.826 41.929 1.00 128.80 ? 203 GLU C CA 1 +ATOM 5286 C C . GLU C 1 203 ? 9.696 -70.645 41.717 1.00 117.12 ? 203 GLU C C 1 +ATOM 5287 O O . GLU C 1 203 ? 9.441 -70.219 40.588 1.00 115.07 ? 203 GLU C O 1 +ATOM 5288 C CB . GLU C 1 203 ? 12.095 -71.321 41.884 1.00 129.79 ? 203 GLU C CB 1 +ATOM 5289 C CG . GLU C 1 203 ? 13.110 -72.374 42.325 1.00 139.53 ? 203 GLU C CG 1 +ATOM 5290 C CD . GLU C 1 203 ? 13.446 -72.401 43.816 1.00 146.38 ? 203 GLU C CD 1 +ATOM 5291 O OE1 . GLU C 1 203 ? 13.578 -71.351 44.463 1.00 146.43 ? 203 GLU C OE1 1 +ATOM 5292 O OE2 . GLU C 1 203 ? 13.633 -73.503 44.361 1.00 164.87 ? 203 GLU C OE2 1 +ATOM 5293 N N . VAL C 1 204 ? 9.186 -70.125 42.828 1.00 109.48 ? 204 VAL C N 1 +ATOM 5294 C CA . VAL C 1 204 ? 8.449 -68.864 42.854 1.00 115.13 ? 204 VAL C CA 1 +ATOM 5295 C C . VAL C 1 204 ? 9.145 -67.921 43.828 1.00 106.12 ? 204 VAL C C 1 +ATOM 5296 O O . VAL C 1 204 ? 9.536 -68.322 44.926 1.00 113.80 ? 204 VAL C O 1 +ATOM 5297 C CB . VAL C 1 204 ? 6.964 -69.076 43.270 1.00 118.50 ? 204 VAL C CB 1 +ATOM 5298 C CG1 . VAL C 1 204 ? 6.286 -67.766 43.682 1.00 95.51 ? 204 VAL C CG1 1 +ATOM 5299 C CG2 . VAL C 1 204 ? 6.195 -69.744 42.134 1.00 109.98 ? 204 VAL C CG2 1 +ATOM 5300 N N . GLY C 1 205 ? 9.288 -66.671 43.415 1.00 115.47 ? 205 GLY C N 1 +ATOM 5301 C CA . GLY C 1 205 ? 9.849 -65.638 44.271 1.00 130.57 ? 205 GLY C CA 1 +ATOM 5302 C C . GLY C 1 205 ? 9.087 -64.322 44.184 1.00 128.69 ? 205 GLY C C 1 +ATOM 5303 O O . GLY C 1 205 ? 8.489 -64.002 43.152 1.00 105.22 ? 205 GLY C O 1 +ATOM 5304 N N . TYR C 1 206 ? 9.104 -63.561 45.275 1.00 117.62 ? 206 TYR C N 1 +ATOM 5305 C CA . TYR C 1 206 ? 8.496 -62.232 45.309 1.00 109.64 ? 206 TYR C CA 1 +ATOM 5306 C C . TYR C 1 206 ? 9.276 -61.330 46.252 1.00 123.48 ? 206 TYR C C 1 +ATOM 5307 O O . TYR C 1 206 ? 9.707 -61.765 47.310 1.00 160.97 ? 206 TYR C O 1 +ATOM 5308 C CB . TYR C 1 206 ? 7.033 -62.308 45.767 1.00 95.73 ? 206 TYR C CB 1 +ATOM 5309 C CG . TYR C 1 206 ? 6.367 -60.964 45.889 1.00 100.80 ? 206 TYR C CG 1 +ATOM 5310 C CD1 . TYR C 1 206 ? 5.967 -60.257 44.747 1.00 110.83 ? 206 TYR C CD1 1 +ATOM 5311 C CD2 . TYR C 1 206 ? 6.164 -60.373 47.132 1.00 88.78 ? 206 TYR C CD2 1 +ATOM 5312 C CE1 . TYR C 1 206 ? 5.392 -58.998 44.845 1.00 114.58 ? 206 TYR C CE1 1 +ATOM 5313 C CE2 . TYR C 1 206 ? 5.590 -59.115 47.238 1.00 108.89 ? 206 TYR C CE2 1 +ATOM 5314 C CZ . TYR C 1 206 ? 5.214 -58.427 46.098 1.00 122.86 ? 206 TYR C CZ 1 +ATOM 5315 O OH . TYR C 1 206 ? 4.619 -57.183 46.209 1.00 149.39 ? 206 TYR C OH 1 +ATOM 5316 N N . THR C 1 207 ? 9.447 -60.064 45.877 1.00 113.90 ? 207 THR C N 1 +ATOM 5317 C CA . THR C 1 207 ? 10.132 -59.097 46.736 1.00 92.25 ? 207 THR C CA 1 +ATOM 5318 C C . THR C 1 207 ? 9.372 -57.768 46.742 1.00 67.37 ? 207 THR C C 1 +ATOM 5319 O O . THR C 1 207 ? 8.957 -57.274 45.692 1.00 44.99 ? 207 THR C O 1 +ATOM 5320 C CB . THR C 1 207 ? 11.594 -58.876 46.284 1.00 110.95 ? 207 THR C CB 1 +ATOM 5321 O OG1 . THR C 1 207 ? 11.611 -58.345 44.956 1.00 137.36 ? 207 THR C OG1 1 +ATOM 5322 C CG2 . THR C 1 207 ? 12.373 -60.174 46.300 1.00 107.83 ? 207 THR C CG2 1 +ATOM 5323 N N . SER C 1 208 ? 9.266 -57.156 47.916 1.00 70.30 ? 208 SER C N 1 +ATOM 5324 C CA . SER C 1 208 ? 8.667 -55.824 48.020 1.00 91.52 ? 208 SER C CA 1 +ATOM 5325 C C . SER C 1 208 ? 9.507 -54.825 48.865 1.00 122.87 ? 208 SER C C 1 +ATOM 5326 O O . SER C 1 208 ? 9.826 -55.094 50.014 1.00 112.78 ? 208 SER C O 1 +ATOM 5327 C CB . SER C 1 208 ? 7.256 -55.933 48.584 1.00 74.76 ? 208 SER C CB 1 +ATOM 5328 O OG . SER C 1 208 ? 6.692 -54.651 48.798 1.00 78.08 ? 208 SER C OG 1 +ATOM 5329 N N . ASN C 1 209 ? 9.810 -53.664 48.276 1.00 132.77 ? 209 ASN C N 1 +ATOM 5330 C CA . ASN C 1 209 ? 10.430 -52.545 48.973 1.00 110.12 ? 209 ASN C CA 1 +ATOM 5331 C C . ASN C 1 209 ? 9.470 -51.376 49.073 1.00 114.67 ? 209 ASN C C 1 +ATOM 5332 O O . ASN C 1 209 ? 8.821 -50.998 48.090 1.00 98.14 ? 209 ASN C O 1 +ATOM 5333 C CB . ASN C 1 209 ? 11.659 -52.061 48.219 1.00 111.81 ? 209 ASN C CB 1 +ATOM 5334 C CG . ASN C 1 209 ? 12.785 -53.039 48.279 1.00 127.51 ? 209 ASN C CG 1 +ATOM 5335 O OD1 . ASN C 1 209 ? 13.552 -53.071 49.243 1.00 126.18 ? 209 ASN C OD1 1 +ATOM 5336 N ND2 . ASN C 1 209 ? 12.914 -53.834 47.228 1.00 149.48 ? 209 ASN C ND2 1 +ATOM 5337 N N . GLU C 1 210 ? 9.446 -50.737 50.237 1.00 129.27 ? 210 GLU C N 1 +ATOM 5338 C CA . GLU C 1 210 ? 8.799 -49.428 50.358 1.00 129.41 ? 210 GLU C CA 1 +ATOM 5339 C C . GLU C 1 210 ? 9.624 -48.374 49.600 1.00 150.69 ? 210 GLU C C 1 +ATOM 5340 O O . GLU C 1 210 ? 10.854 -48.432 49.593 1.00 155.24 ? 210 GLU C O 1 +ATOM 5341 C CB . GLU C 1 210 ? 8.673 -49.030 51.829 1.00 119.47 ? 210 GLU C CB 1 +ATOM 5342 C CG . GLU C 1 210 ? 7.325 -48.458 52.231 1.00 96.61 ? 210 GLU C CG 1 +ATOM 5343 C CD . GLU C 1 210 ? 7.137 -48.465 53.749 1.00 91.23 ? 210 GLU C CD 1 +ATOM 5344 O OE1 . GLU C 1 210 ? 7.726 -49.340 54.464 1.00 56.39 ? 210 GLU C OE1 1 +ATOM 5345 O OE2 . GLU C 1 210 ? 6.338 -47.620 54.204 1.00 79.78 ? 210 GLU C OE2 1 +ATOM 5346 N N . PRO C 1 211 ? 8.949 -47.438 48.909 1.00 149.58 ? 211 PRO C N 1 +ATOM 5347 C CA . PRO C 1 211 ? 9.681 -46.332 48.308 1.00 129.97 ? 211 PRO C CA 1 +ATOM 5348 C C . PRO C 1 211 ? 10.158 -45.341 49.365 1.00 95.52 ? 211 PRO C C 1 +ATOM 5349 O O . PRO C 1 211 ? 9.361 -44.864 50.191 1.00 73.39 ? 211 PRO C O 1 +ATOM 5350 C CB . PRO C 1 211 ? 8.638 -45.685 47.379 1.00 144.45 ? 211 PRO C CB 1 +ATOM 5351 C CG . PRO C 1 211 ? 7.581 -46.710 47.181 1.00 118.47 ? 211 PRO C CG 1 +ATOM 5352 C CD . PRO C 1 211 ? 7.539 -47.446 48.486 1.00 140.13 ? 211 PRO C CD 1 +ATOM 5353 N N . VAL C 1 212 ? 11.450 -45.068 49.359 1.00 75.05 ? 212 VAL C N 1 +ATOM 5354 C CA . VAL C 1 212 ? 12.029 -44.134 50.322 1.00 100.75 ? 212 VAL C CA 1 +ATOM 5355 C C . VAL C 1 212 ? 11.405 -42.775 50.063 1.00 104.43 ? 212 VAL C C 1 +ATOM 5356 O O . VAL C 1 212 ? 11.147 -41.988 50.984 1.00 117.28 ? 212 VAL C O 1 +ATOM 5357 C CB . VAL C 1 212 ? 13.582 -44.056 50.172 1.00 118.60 ? 212 VAL C CB 1 +ATOM 5358 C CG1 . VAL C 1 212 ? 14.193 -43.155 51.251 1.00 90.95 ? 212 VAL C CG1 1 +ATOM 5359 C CG2 . VAL C 1 212 ? 14.214 -45.455 50.218 1.00 136.77 ? 212 VAL C CG2 1 +ATOM 5360 N N . MET C 1 213 ? 11.304 -42.469 48.769 1.00 108.03 ? 213 MET C N 1 +ATOM 5361 C CA . MET C 1 213 ? 10.560 -41.330 48.214 1.00 91.17 ? 213 MET C CA 1 +ATOM 5362 C C . MET C 1 213 ? 9.245 -41.056 48.973 1.00 109.98 ? 213 MET C C 1 +ATOM 5363 O O . MET C 1 213 ? 8.967 -39.937 49.435 1.00 84.93 ? 213 MET C O 1 +ATOM 5364 C CB . MET C 1 213 ? 10.294 -41.742 46.783 1.00 74.06 ? 213 MET C CB 1 +ATOM 5365 C CG . MET C 1 213 ? 9.582 -40.767 45.915 1.00 86.15 ? 213 MET C CG 1 +ATOM 5366 S SD . MET C 1 213 ? 9.432 -41.563 44.297 1.00 105.36 ? 213 MET C SD 1 +ATOM 5367 C CE . MET C 1 213 ? 7.635 -41.805 44.377 1.00 134.54 ? 213 MET C CE 1 +ATOM 5368 N N . LEU C 1 214 ? 8.500 -42.128 49.195 1.00 125.75 ? 214 LEU C N 1 +ATOM 5369 C CA . LEU C 1 214 ? 7.135 -42.028 49.664 1.00 127.72 ? 214 LEU C CA 1 +ATOM 5370 C C . LEU C 1 214 ? 7.133 -41.910 51.192 1.00 136.65 ? 214 LEU C C 1 +ATOM 5371 O O . LEU C 1 214 ? 6.224 -41.322 51.787 1.00 138.05 ? 214 LEU C O 1 +ATOM 5372 C CB . LEU C 1 214 ? 6.350 -43.263 49.200 1.00 135.46 ? 214 LEU C CB 1 +ATOM 5373 C CG . LEU C 1 214 ? 4.942 -43.071 48.644 1.00 131.56 ? 214 LEU C CG 1 +ATOM 5374 C CD1 . LEU C 1 214 ? 4.913 -42.166 47.422 1.00 99.79 ? 214 LEU C CD1 1 +ATOM 5375 C CD2 . LEU C 1 214 ? 4.338 -44.439 48.323 1.00 135.35 ? 214 LEU C CD2 1 +ATOM 5376 N N . CYS C 1 215 ? 8.142 -42.502 51.827 1.00 128.02 ? 215 CYS C N 1 +ATOM 5377 C CA . CYS C 1 215 ? 8.289 -42.428 53.283 1.00 131.57 ? 215 CYS C CA 1 +ATOM 5378 C C . CYS C 1 215 ? 8.701 -41.023 53.702 1.00 137.02 ? 215 CYS C C 1 +ATOM 5379 O O . CYS C 1 215 ? 8.249 -40.488 54.728 1.00 133.87 ? 215 CYS C O 1 +ATOM 5380 C CB . CYS C 1 215 ? 9.349 -43.420 53.757 1.00 112.50 ? 215 CYS C CB 1 +ATOM 5381 S SG . CYS C 1 215 ? 8.904 -45.134 53.500 1.00 134.14 ? 215 CYS C SG 1 +ATOM 5382 N N . LEU C 1 216 ? 9.624 -40.459 52.929 1.00 117.86 ? 216 LEU C N 1 +ATOM 5383 C CA . LEU C 1 216 ? 10.033 -39.093 53.141 1.00 84.46 ? 216 LEU C CA 1 +ATOM 5384 C C . LEU C 1 216 ? 8.801 -38.216 53.095 1.00 79.98 ? 216 LEU C C 1 +ATOM 5385 O O . LEU C 1 216 ? 8.590 -37.363 53.963 1.00 69.67 ? 216 LEU C O 1 +ATOM 5386 C CB . LEU C 1 216 ? 11.054 -38.668 52.082 1.00 94.46 ? 216 LEU C CB 1 +ATOM 5387 C CG . LEU C 1 216 ? 11.541 -37.213 52.167 1.00 106.13 ? 216 LEU C CG 1 +ATOM 5388 C CD1 . LEU C 1 216 ? 12.141 -36.883 53.524 1.00 120.16 ? 216 LEU C CD1 1 +ATOM 5389 C CD2 . LEU C 1 216 ? 12.556 -36.911 51.074 1.00 99.29 ? 216 LEU C CD2 1 +ATOM 5390 N N . MET C 1 217 ? 7.984 -38.411 52.059 1.00 102.97 ? 217 MET C N 1 +ATOM 5391 C CA . MET C 1 217 ? 6.818 -37.545 51.835 1.00 126.78 ? 217 MET C CA 1 +ATOM 5392 C C . MET C 1 217 ? 5.852 -37.667 53.010 1.00 121.49 ? 217 MET C C 1 +ATOM 5393 O O . MET C 1 217 ? 5.413 -36.653 53.564 1.00 117.33 ? 217 MET C O 1 +ATOM 5394 C CB . MET C 1 217 ? 6.112 -37.882 50.508 1.00 120.65 ? 217 MET C CB 1 +ATOM 5395 C CG . MET C 1 217 ? 5.686 -36.650 49.709 1.00 103.06 ? 217 MET C CG 1 +ATOM 5396 S SD . MET C 1 217 ? 4.353 -35.739 50.506 1.00 99.79 ? 217 MET C SD 1 +ATOM 5397 C CE . MET C 1 217 ? 4.273 -34.239 49.528 1.00 117.68 ? 217 MET C CE 1 +ATOM 5398 N N . SER C 1 218 ? 5.601 -38.904 53.427 1.00 107.95 ? 218 SER C N 1 +ATOM 5399 C CA . SER C 1 218 ? 4.730 -39.177 54.556 1.00 119.70 ? 218 SER C CA 1 +ATOM 5400 C C . SER C 1 218 ? 5.204 -38.437 55.811 1.00 128.55 ? 218 SER C C 1 +ATOM 5401 O O . SER C 1 218 ? 4.412 -37.771 56.498 1.00 112.20 ? 218 SER C O 1 +ATOM 5402 C CB . SER C 1 218 ? 4.680 -40.686 54.820 1.00 116.39 ? 218 SER C CB 1 +ATOM 5403 O OG . SER C 1 218 ? 3.659 -41.001 55.762 1.00 162.67 ? 218 SER C OG 1 +ATOM 5404 N N . ALA C 1 219 ? 6.491 -38.575 56.116 1.00 136.58 ? 219 ALA C N 1 +ATOM 5405 C CA . ALA C 1 219 ? 7.052 -38.036 57.359 1.00 131.61 ? 219 ALA C CA 1 +ATOM 5406 C C . ALA C 1 219 ? 7.029 -36.505 57.381 1.00 108.82 ? 219 ALA C C 1 +ATOM 5407 O O . ALA C 1 219 ? 6.768 -35.880 58.410 1.00 98.40 ? 219 ALA C O 1 +ATOM 5408 C CB . ALA C 1 219 ? 8.464 -38.545 57.537 1.00 123.28 ? 219 ALA C CB 1 +ATOM 5409 N N . ILE C 1 220 ? 7.192 -35.905 56.215 1.00 102.99 ? 220 ILE C N 1 +ATOM 5410 C CA . ILE C 1 220 ? 7.092 -34.456 56.104 1.00 104.38 ? 220 ILE C CA 1 +ATOM 5411 C C . ILE C 1 220 ? 5.667 -33.968 56.378 1.00 110.77 ? 220 ILE C C 1 +ATOM 5412 O O . ILE C 1 220 ? 5.464 -32.951 57.051 1.00 98.44 ? 220 ILE C O 1 +ATOM 5413 C CB . ILE C 1 220 ? 7.579 -33.962 54.718 1.00 112.40 ? 220 ILE C CB 1 +ATOM 5414 C CG1 . ILE C 1 220 ? 9.097 -34.183 54.598 1.00 102.13 ? 220 ILE C CG1 1 +ATOM 5415 C CG2 . ILE C 1 220 ? 7.232 -32.489 54.506 1.00 104.09 ? 220 ILE C CG2 1 +ATOM 5416 C CD1 . ILE C 1 220 ? 9.630 -34.116 53.187 1.00 91.55 ? 220 ILE C CD1 1 +ATOM 5417 N N . GLU C 1 221 ? 4.674 -34.683 55.846 1.00 135.96 ? 221 GLU C N 1 +ATOM 5418 C CA . GLU C 1 221 ? 3.253 -34.349 56.092 1.00 137.37 ? 221 GLU C CA 1 +ATOM 5419 C C . GLU C 1 221 ? 2.932 -34.382 57.588 1.00 116.46 ? 221 GLU C C 1 +ATOM 5420 O O . GLU C 1 221 ? 2.433 -33.404 58.153 1.00 79.34 ? 221 GLU C O 1 +ATOM 5421 C CB . GLU C 1 221 ? 2.341 -35.332 55.355 1.00 137.86 ? 221 GLU C CB 1 +ATOM 5422 C CG . GLU C 1 221 ? 2.277 -35.109 53.854 1.00 157.44 ? 221 GLU C CG 1 +ATOM 5423 C CD . GLU C 1 221 ? 1.715 -36.301 53.086 1.00 157.22 ? 221 GLU C CD 1 +ATOM 5424 O OE1 . GLU C 1 221 ? 2.001 -37.474 53.453 1.00 102.70 ? 221 GLU C OE1 1 +ATOM 5425 O OE2 . GLU C 1 221 ? 1.037 -36.036 52.067 1.00 156.15 ? 221 GLU C OE2 1 +ATOM 5426 N N . THR C 1 222 ? 3.316 -35.491 58.218 1.00 99.24 ? 222 THR C N 1 +ATOM 5427 C CA . THR C 1 222 ? 3.208 -35.668 59.657 1.00 86.89 ? 222 THR C CA 1 +ATOM 5428 C C . THR C 1 222 ? 3.808 -34.485 60.408 1.00 95.08 ? 222 THR C C 1 +ATOM 5429 O O . THR C 1 222 ? 3.194 -33.951 61.343 1.00 87.48 ? 222 THR C O 1 +ATOM 5430 C CB . THR C 1 222 ? 3.949 -36.958 60.094 1.00 85.92 ? 222 THR C CB 1 +ATOM 5431 O OG1 . THR C 1 222 ? 3.221 -38.107 59.631 1.00 92.33 ? 222 THR C OG1 1 +ATOM 5432 C CG2 . THR C 1 222 ? 4.145 -37.009 61.627 1.00 81.54 ? 222 THR C CG2 1 +ATOM 5433 N N . GLY C 1 223 ? 5.037 -34.116 60.032 1.00 99.61 ? 223 GLY C N 1 +ATOM 5434 C CA . GLY C 1 223 ? 5.718 -32.957 60.619 1.00 105.49 ? 223 GLY C CA 1 +ATOM 5435 C C . GLY C 1 223 ? 4.933 -31.653 60.489 1.00 102.93 ? 223 GLY C C 1 +ATOM 5436 O O . GLY C 1 223 ? 4.854 -30.867 61.446 1.00 89.43 ? 223 GLY C O 1 +ATOM 5437 N N . VAL C 1 224 ? 4.290 -31.467 59.339 1.00 86.78 ? 224 VAL C N 1 +ATOM 5438 C CA . VAL C 1 224 ? 3.493 -30.282 59.122 1.00 92.83 ? 224 VAL C CA 1 +ATOM 5439 C C . VAL C 1 224 ? 2.318 -30.259 60.091 1.00 122.16 ? 224 VAL C C 1 +ATOM 5440 O O . VAL C 1 224 ? 1.993 -29.209 60.662 1.00 133.91 ? 224 VAL C O 1 +ATOM 5441 C CB . VAL C 1 224 ? 2.973 -30.201 57.683 1.00 90.45 ? 224 VAL C CB 1 +ATOM 5442 C CG1 . VAL C 1 224 ? 2.006 -29.036 57.534 1.00 88.27 ? 224 VAL C CG1 1 +ATOM 5443 C CG2 . VAL C 1 224 ? 4.136 -30.049 56.713 1.00 103.18 ? 224 VAL C CG2 1 +ATOM 5444 N N . ILE C 1 225 ? 1.685 -31.413 60.289 1.00 148.49 ? 225 ILE C N 1 +ATOM 5445 C CA . ILE C 1 225 ? 0.559 -31.500 61.225 1.00 150.73 ? 225 ILE C CA 1 +ATOM 5446 C C . ILE C 1 225 ? 1.000 -31.139 62.638 1.00 139.46 ? 225 ILE C C 1 +ATOM 5447 O O . ILE C 1 225 ? 0.399 -30.252 63.252 1.00 118.30 ? 225 ILE C O 1 +ATOM 5448 C CB . ILE C 1 225 ? -0.094 -32.894 61.233 1.00 145.66 ? 225 ILE C CB 1 +ATOM 5449 C CG1 . ILE C 1 225 ? -0.794 -33.153 59.896 1.00 180.71 ? 225 ILE C CG1 1 +ATOM 5450 C CG2 . ILE C 1 225 ? -1.117 -32.995 62.356 1.00 118.31 ? 225 ILE C CG2 1 +ATOM 5451 C CD1 . ILE C 1 225 ? -1.089 -34.615 59.637 1.00 204.15 ? 225 ILE C CD1 1 +ATOM 5452 N N . PHE C 1 226 ? 2.060 -31.790 63.127 1.00 123.18 ? 226 PHE C N 1 +ATOM 5453 C CA . PHE C 1 226 ? 2.615 -31.479 64.454 1.00 132.01 ? 226 PHE C CA 1 +ATOM 5454 C C . PHE C 1 226 ? 2.975 -29.989 64.605 1.00 147.47 ? 226 PHE C C 1 +ATOM 5455 O O . PHE C 1 226 ? 2.832 -29.415 65.688 1.00 165.20 ? 226 PHE C O 1 +ATOM 5456 C CB . PHE C 1 226 ? 3.855 -32.324 64.759 1.00 131.22 ? 226 PHE C CB 1 +ATOM 5457 C CG . PHE C 1 226 ? 3.554 -33.734 65.199 1.00 113.13 ? 226 PHE C CG 1 +ATOM 5458 C CD1 . PHE C 1 226 ? 2.834 -33.971 66.343 1.00 118.80 ? 226 PHE C CD1 1 +ATOM 5459 C CD2 . PHE C 1 226 ? 4.094 -34.825 64.508 1.00 114.78 ? 226 PHE C CD2 1 +ATOM 5460 C CE1 . PHE C 1 226 ? 2.591 -35.272 66.754 1.00 150.00 ? 226 PHE C CE1 1 +ATOM 5461 C CE2 . PHE C 1 226 ? 3.898 -36.125 64.939 1.00 96.82 ? 226 PHE C CE2 1 +ATOM 5462 C CZ . PHE C 1 226 ? 3.123 -36.349 66.047 1.00 120.79 ? 226 PHE C CZ 1 +ATOM 5463 N N . LEU C 1 227 ? 3.438 -29.365 63.525 1.00 125.05 ? 227 LEU C N 1 +ATOM 5464 C CA . LEU C 1 227 ? 3.725 -27.940 63.538 1.00 117.04 ? 227 LEU C CA 1 +ATOM 5465 C C . LEU C 1 227 ? 2.455 -27.115 63.722 1.00 142.13 ? 227 LEU C C 1 +ATOM 5466 O O . LEU C 1 227 ? 2.443 -26.153 64.494 1.00 146.61 ? 227 LEU C O 1 +ATOM 5467 C CB . LEU C 1 227 ? 4.428 -27.551 62.241 1.00 108.13 ? 227 LEU C CB 1 +ATOM 5468 C CG . LEU C 1 227 ? 5.910 -27.920 62.150 1.00 115.00 ? 227 LEU C CG 1 +ATOM 5469 C CD1 . LEU C 1 227 ? 6.520 -27.802 60.773 1.00 118.55 ? 227 LEU C CD1 1 +ATOM 5470 C CD2 . LEU C 1 227 ? 6.737 -27.110 63.126 1.00 126.63 ? 227 LEU C CD2 1 +ATOM 5471 N N . ILE C 1 228 ? 1.396 -27.463 62.988 1.00 138.87 ? 228 ILE C N 1 +ATOM 5472 C CA . ILE C 1 228 ? 0.139 -26.712 63.056 1.00 123.88 ? 228 ILE C CA 1 +ATOM 5473 C C . ILE C 1 228 ? -0.447 -26.852 64.454 1.00 120.59 ? 228 ILE C C 1 +ATOM 5474 O O . ILE C 1 228 ? -0.856 -25.866 65.074 1.00 86.83 ? 228 ILE C O 1 +ATOM 5475 C CB . ILE C 1 228 ? -0.903 -27.187 62.020 1.00 103.07 ? 228 ILE C CB 1 +ATOM 5476 C CG1 . ILE C 1 228 ? -0.411 -26.924 60.601 1.00 121.93 ? 228 ILE C CG1 1 +ATOM 5477 C CG2 . ILE C 1 228 ? -2.213 -26.444 62.212 1.00 86.71 ? 228 ILE C CG2 1 +ATOM 5478 C CD1 . ILE C 1 228 ? -1.173 -27.673 59.527 1.00 139.66 ? 228 ILE C CD1 1 +ATOM 5479 N N . ASN C 1 229 ? -0.490 -28.085 64.944 1.00 127.67 ? 229 ASN C N 1 +ATOM 5480 C CA . ASN C 1 229 ? -1.058 -28.366 66.259 1.00 144.10 ? 229 ASN C CA 1 +ATOM 5481 C C . ASN C 1 229 ? -0.281 -27.604 67.328 1.00 144.73 ? 229 ASN C C 1 +ATOM 5482 O O . ASN C 1 229 ? -0.871 -27.008 68.234 1.00 130.89 ? 229 ASN C O 1 +ATOM 5483 C CB . ASN C 1 229 ? -1.032 -29.877 66.525 1.00 152.30 ? 229 ASN C CB 1 +ATOM 5484 C CG . ASN C 1 229 ? -1.927 -30.287 67.671 1.00 163.78 ? 229 ASN C CG 1 +ATOM 5485 O OD1 . ASN C 1 229 ? -2.895 -29.596 68.010 1.00 170.63 ? 229 ASN C OD1 1 +ATOM 5486 N ND2 . ASN C 1 229 ? -1.631 -31.441 68.256 1.00 172.28 ? 229 ASN C ND2 1 +ATOM 5487 N N . ASP C 1 230 ? 1.045 -27.610 67.197 1.00 142.29 ? 230 ASP C N 1 +ATOM 5488 C CA . ASP C 1 230 ? 1.925 -26.930 68.146 1.00 147.34 ? 230 ASP C CA 1 +ATOM 5489 C C . ASP C 1 230 ? 1.675 -25.432 68.118 1.00 121.51 ? 230 ASP C C 1 +ATOM 5490 O O . ASP C 1 230 ? 1.601 -24.784 69.170 1.00 146.37 ? 230 ASP C O 1 +ATOM 5491 C CB . ASP C 1 230 ? 3.393 -27.212 67.810 1.00 162.06 ? 230 ASP C CB 1 +ATOM 5492 C CG . ASP C 1 230 ? 4.352 -26.626 68.836 1.00 179.86 ? 230 ASP C CG 1 +ATOM 5493 O OD1 . ASP C 1 230 ? 4.418 -27.174 69.954 1.00 214.46 ? 230 ASP C OD1 1 +ATOM 5494 O OD2 . ASP C 1 230 ? 5.007 -25.612 68.547 1.00 150.37 ? 230 ASP C OD2 1 +ATOM 5495 N N . GLY C 1 231 ? 1.478 -24.902 66.920 1.00 103.02 ? 231 GLY C N 1 +ATOM 5496 C CA . GLY C 1 231 ? 1.176 -23.483 66.762 1.00 134.84 ? 231 GLY C CA 1 +ATOM 5497 C C . GLY C 1 231 ? -0.191 -23.074 67.299 1.00 142.26 ? 231 GLY C C 1 +ATOM 5498 O O . GLY C 1 231 ? -0.343 -21.989 67.884 1.00 105.81 ? 231 GLY C O 1 +ATOM 5499 N N . ILE C 1 232 ? -1.158 -23.988 67.200 1.00 173.44 ? 232 ILE C N 1 +ATOM 5500 C CA . ILE C 1 232 ? -2.476 -23.798 67.823 1.00 168.20 ? 232 ILE C CA 1 +ATOM 5501 C C . ILE C 1 232 ? -2.360 -23.682 69.344 1.00 165.21 ? 232 ILE C C 1 +ATOM 5502 O O . ILE C 1 232 ? -2.863 -22.720 69.926 1.00 156.79 ? 232 ILE C O 1 +ATOM 5503 C CB . ILE C 1 232 ? -3.449 -24.950 67.471 1.00 159.91 ? 232 ILE C CB 1 +ATOM 5504 C CG1 . ILE C 1 232 ? -3.868 -24.835 66.001 1.00 174.18 ? 232 ILE C CG1 1 +ATOM 5505 C CG2 . ILE C 1 232 ? -4.673 -24.939 68.384 1.00 139.38 ? 232 ILE C CG2 1 +ATOM 5506 C CD1 . ILE C 1 232 ? -4.463 -26.104 65.431 1.00 178.20 ? 232 ILE C CD1 1 +ATOM 5507 N N . ASP C 1 233 ? -1.671 -24.644 69.965 1.00 165.17 ? 233 ASP C N 1 +ATOM 5508 C CA . ASP C 1 233 ? -1.399 -24.624 71.413 1.00 153.14 ? 233 ASP C CA 1 +ATOM 5509 C C . ASP C 1 233 ? -0.701 -23.336 71.866 1.00 145.30 ? 233 ASP C C 1 +ATOM 5510 O O . ASP C 1 233 ? -1.152 -22.675 72.792 1.00 166.16 ? 233 ASP C O 1 +ATOM 5511 C CB . ASP C 1 233 ? -0.526 -25.816 71.821 1.00 150.74 ? 233 ASP C CB 1 +ATOM 5512 C CG . ASP C 1 233 ? -1.217 -27.156 71.610 1.00 179.63 ? 233 ASP C CG 1 +ATOM 5513 O OD1 . ASP C 1 233 ? -2.302 -27.196 70.973 1.00 199.02 ? 233 ASP C OD1 1 +ATOM 5514 O OD2 . ASP C 1 233 ? -0.668 -28.181 72.076 1.00 176.77 ? 233 ASP C OD2 1 +ATOM 5515 N N . ARG C 1 234 ? 0.361 -22.949 71.165 1.00 129.53 ? 234 ARG C N 1 +ATOM 5516 C CA . ARG C 1 234 ? 1.173 -21.795 71.569 1.00 98.55 ? 234 ARG C CA 1 +ATOM 5517 C C . ARG C 1 234 ? 0.587 -20.429 71.182 1.00 122.40 ? 234 ARG C C 1 +ATOM 5518 O O . ARG C 1 234 ? 1.199 -19.393 71.441 1.00 135.30 ? 234 ARG C O 1 +ATOM 5519 C CB . ARG C 1 234 ? 2.576 -21.952 71.007 1.00 84.19 ? 234 ARG C CB 1 +ATOM 5520 C CG . ARG C 1 234 ? 3.345 -23.030 71.724 1.00 93.82 ? 234 ARG C CG 1 +ATOM 5521 C CD . ARG C 1 234 ? 4.509 -23.579 70.904 1.00 97.07 ? 234 ARG C CD 1 +ATOM 5522 N NE . ARG C 1 234 ? 5.163 -24.667 71.619 1.00 95.06 ? 234 ARG C NE 1 +ATOM 5523 C CZ . ARG C 1 234 ? 6.414 -24.634 72.053 1.00 100.12 ? 234 ARG C CZ 1 +ATOM 5524 N NH1 . ARG C 1 234 ? 7.197 -23.616 71.739 1.00 107.82 ? 234 ARG C NH1 1 +ATOM 5525 N NH2 . ARG C 1 234 ? 6.897 -25.649 72.758 1.00 108.16 ? 234 ARG C NH2 1 +ATOM 5526 N N . GLY C 1 235 ? -0.555 -20.426 70.491 1.00 133.03 ? 235 GLY C N 1 +ATOM 5527 C CA . GLY C 1 235 ? -1.204 -19.183 70.082 1.00 137.94 ? 235 GLY C CA 1 +ATOM 5528 C C . GLY C 1 235 ? -0.539 -18.462 68.912 1.00 160.72 ? 235 GLY C C 1 +ATOM 5529 O O . GLY C 1 235 ? -0.550 -17.226 68.854 1.00 154.08 ? 235 GLY C O 1 +ATOM 5530 N N . LEU C 1 236 ? 0.056 -19.213 67.983 1.00 158.74 ? 236 LEU C N 1 +ATOM 5531 C CA . LEU C 1 236 ? 0.519 -18.619 66.720 1.00 137.70 ? 236 LEU C CA 1 +ATOM 5532 C C . LEU C 1 236 ? -0.696 -18.319 65.853 1.00 143.59 ? 236 LEU C C 1 +ATOM 5533 O O . LEU C 1 236 ? -0.826 -17.227 65.298 1.00 137.84 ? 236 LEU C O 1 +ATOM 5534 C CB . LEU C 1 236 ? 1.490 -19.546 65.964 1.00 123.73 ? 236 LEU C CB 1 +ATOM 5535 C CG . LEU C 1 236 ? 2.973 -19.512 66.369 1.00 113.75 ? 236 LEU C CG 1 +ATOM 5536 C CD1 . LEU C 1 236 ? 3.204 -20.313 67.632 1.00 127.31 ? 236 LEU C CD1 1 +ATOM 5537 C CD2 . LEU C 1 236 ? 3.831 -20.071 65.244 1.00 125.16 ? 236 LEU C CD2 1 +ATOM 5538 N N . TRP C 1 237 ? -1.581 -19.302 65.732 1.00 163.82 ? 237 TRP C N 1 +ATOM 5539 C CA . TRP C 1 237 ? -2.770 -19.175 64.887 1.00 172.45 ? 237 TRP C CA 1 +ATOM 5540 C C . TRP C 1 237 ? -3.982 -19.805 65.579 1.00 186.40 ? 237 TRP C C 1 +ATOM 5541 O O . TRP C 1 237 ? -3.824 -20.566 66.540 1.00 151.42 ? 237 TRP C O 1 +ATOM 5542 C CB . TRP C 1 237 ? -2.514 -19.813 63.516 1.00 152.94 ? 237 TRP C CB 1 +ATOM 5543 C CG . TRP C 1 237 ? -1.597 -21.000 63.586 1.00 141.74 ? 237 TRP C CG 1 +ATOM 5544 C CD1 . TRP C 1 237 ? -1.856 -22.194 64.182 1.00 142.41 ? 237 TRP C CD1 1 +ATOM 5545 C CD2 . TRP C 1 237 ? -0.267 -21.094 63.061 1.00 130.79 ? 237 TRP C CD2 1 +ATOM 5546 N NE1 . TRP C 1 237 ? -0.781 -23.032 64.049 1.00 137.24 ? 237 TRP C NE1 1 +ATOM 5547 C CE2 . TRP C 1 237 ? 0.203 -22.387 63.349 1.00 124.18 ? 237 TRP C CE2 1 +ATOM 5548 C CE3 . TRP C 1 237 ? 0.561 -20.218 62.356 1.00 142.03 ? 237 TRP C CE3 1 +ATOM 5549 C CZ2 . TRP C 1 237 ? 1.467 -22.830 62.957 1.00 111.95 ? 237 TRP C CZ2 1 +ATOM 5550 C CZ3 . TRP C 1 237 ? 1.822 -20.660 61.976 1.00 141.14 ? 237 TRP C CZ3 1 +ATOM 5551 C CH2 . TRP C 1 237 ? 2.263 -21.953 62.290 1.00 114.68 ? 237 TRP C CH2 1 +ATOM 5552 N N . ASP C 1 238 ? -5.179 -19.494 65.077 1.00 198.61 ? 238 ASP C N 1 +ATOM 5553 C CA . ASP C 1 238 ? -6.427 -19.903 65.731 1.00 183.61 ? 238 ASP C CA 1 +ATOM 5554 C C . ASP C 1 238 ? -7.418 -20.589 64.791 1.00 165.75 ? 238 ASP C C 1 +ATOM 5555 O O . ASP C 1 238 ? -7.478 -20.286 63.590 1.00 163.40 ? 238 ASP C O 1 +ATOM 5556 C CB . ASP C 1 238 ? -7.114 -18.702 66.371 1.00 168.36 ? 238 ASP C CB 1 +ATOM 5557 C CG . ASP C 1 238 ? -6.222 -17.975 67.350 1.00 180.91 ? 238 ASP C CG 1 +ATOM 5558 O OD1 . ASP C 1 238 ? -5.365 -17.194 66.891 1.00 163.76 ? 238 ASP C OD1 1 +ATOM 5559 O OD2 . ASP C 1 238 ? -6.364 -18.187 68.576 1.00 196.60 ? 238 ASP C OD2 1 +ATOM 5560 N N . LEU C 1 239 ? -8.194 -21.517 65.354 1.00 130.79 ? 239 LEU C N 1 +ATOM 5561 C CA . LEU C 1 239 ? -9.165 -22.289 64.587 1.00 125.68 ? 239 LEU C CA 1 +ATOM 5562 C C . LEU C 1 239 ? -10.389 -21.447 64.300 1.00 121.19 ? 239 LEU C C 1 +ATOM 5563 O O . LEU C 1 239 ? -10.795 -20.620 65.121 1.00 150.31 ? 239 LEU C O 1 +ATOM 5564 C CB . LEU C 1 239 ? -9.585 -23.555 65.348 1.00 127.43 ? 239 LEU C CB 1 +ATOM 5565 C CG . LEU C 1 239 ? -8.648 -24.763 65.389 1.00 133.65 ? 239 LEU C CG 1 +ATOM 5566 C CD1 . LEU C 1 239 ? -9.308 -25.934 66.097 1.00 139.32 ? 239 LEU C CD1 1 +ATOM 5567 C CD2 . LEU C 1 239 ? -8.247 -25.174 63.988 1.00 150.74 ? 239 LEU C CD2 1 +ATOM 5568 N N . GLN C 1 240 ? -10.977 -21.665 63.128 1.00 125.56 ? 240 GLN C N 1 +ATOM 5569 C CA . GLN C 1 240 ? -12.275 -21.080 62.800 1.00 148.07 ? 240 GLN C CA 1 +ATOM 5570 C C . GLN C 1 240 ? -13.302 -21.444 63.869 1.00 170.50 ? 240 GLN C C 1 +ATOM 5571 O O . GLN C 1 240 ? -13.917 -20.570 64.487 1.00 158.12 ? 240 GLN C O 1 +ATOM 5572 C CB . GLN C 1 240 ? -12.749 -21.574 61.424 1.00 151.84 ? 240 GLN C CB 1 +ATOM 5573 C CG . GLN C 1 240 ? -13.999 -20.869 60.912 1.00 151.76 ? 240 GLN C CG 1 +ATOM 5574 C CD . GLN C 1 240 ? -13.755 -19.392 60.642 1.00 156.01 ? 240 GLN C CD 1 +ATOM 5575 O OE1 . GLN C 1 240 ? -13.201 -19.024 59.600 1.00 192.76 ? 240 GLN C OE1 1 +ATOM 5576 N NE2 . GLN C 1 240 ? -14.123 -18.542 61.597 1.00 133.28 ? 240 GLN C NE2 1 +ATOM 5577 N N . ASN C 1 241 ? -13.461 -22.746 64.085 1.00 200.66 ? 241 ASN C N 1 +ATOM 5578 C CA . ASN C 1 241 ? -14.382 -23.275 65.084 1.00 196.28 ? 241 ASN C CA 1 +ATOM 5579 C C . ASN C 1 241 ? -13.626 -23.766 66.306 1.00 194.43 ? 241 ASN C C 1 +ATOM 5580 O O . ASN C 1 241 ? -12.947 -24.802 66.252 1.00 194.69 ? 241 ASN C O 1 +ATOM 5581 C CB . ASN C 1 241 ? -15.179 -24.438 64.494 1.00 197.04 ? 241 ASN C CB 1 +ATOM 5582 C CG . ASN C 1 241 ? -16.569 -24.029 64.071 1.00 199.13 ? 241 ASN C CG 1 +ATOM 5583 O OD1 . ASN C 1 241 ? -17.534 -24.304 64.779 1.00 208.28 ? 241 ASN C OD1 1 +ATOM 5584 N ND2 . ASN C 1 241 ? -16.679 -23.343 62.931 1.00 180.84 ? 241 ASN C ND2 1 +ATOM 5585 N N . LYS C 1 242 ? -13.789 -23.053 67.419 1.00 174.56 ? 242 LYS C N 1 +ATOM 5586 C CA . LYS C 1 242 ? -13.121 -23.425 68.665 1.00 167.96 ? 242 LYS C CA 1 +ATOM 5587 C C . LYS C 1 242 ? -13.660 -24.766 69.159 1.00 162.70 ? 242 LYS C C 1 +ATOM 5588 O O . LYS C 1 242 ? -12.956 -25.524 69.839 1.00 93.20 ? 242 LYS C O 1 +ATOM 5589 C CB . LYS C 1 242 ? -13.306 -22.333 69.722 1.00 153.59 ? 242 LYS C CB 1 +ATOM 5590 C CG . LYS C 1 242 ? -12.984 -20.933 69.219 1.00 163.85 ? 242 LYS C CG 1 +ATOM 5591 C CD . LYS C 1 242 ? -11.958 -20.233 70.095 1.00 185.93 ? 242 LYS C CD 1 +ATOM 5592 C CE . LYS C 1 242 ? -10.871 -19.577 69.252 1.00 217.26 ? 242 LYS C CE 1 +ATOM 5593 N NZ . LYS C 1 242 ? -9.934 -18.752 70.063 1.00 228.92 ? 242 LYS C NZ 1 +ATOM 5594 N N . ALA C 1 243 ? -14.897 -25.058 68.749 1.00 194.97 ? 243 ALA C N 1 +ATOM 5595 C CA . ALA C 1 243 ? -15.549 -26.343 68.995 1.00 216.18 ? 243 ALA C CA 1 +ATOM 5596 C C . ALA C 1 243 ? -14.805 -27.494 68.330 1.00 223.90 ? 243 ALA C C 1 +ATOM 5597 O O . ALA C 1 243 ? -15.001 -28.656 68.706 1.00 266.74 ? 243 ALA C O 1 +ATOM 5598 C CB . ALA C 1 243 ? -16.991 -26.306 68.494 1.00 226.39 ? 243 ALA C CB 1 +ATOM 5599 N N . GLU C 1 244 ? -13.974 -27.183 67.333 1.00 201.66 ? 244 GLU C N 1 +ATOM 5600 C CA . GLU C 1 244 ? -13.262 -28.230 66.606 1.00 179.78 ? 244 GLU C CA 1 +ATOM 5601 C C . GLU C 1 244 ? -11.890 -28.517 67.199 1.00 160.17 ? 244 GLU C C 1 +ATOM 5602 O O . GLU C 1 244 ? -11.102 -29.211 66.579 1.00 128.66 ? 244 GLU C O 1 +ATOM 5603 C CB . GLU C 1 244 ? -13.133 -27.870 65.125 1.00 169.75 ? 244 GLU C CB 1 +ATOM 5604 C CG . GLU C 1 244 ? -14.431 -27.989 64.346 1.00 171.55 ? 244 GLU C CG 1 +ATOM 5605 C CD . GLU C 1 244 ? -14.225 -27.886 62.847 1.00 166.03 ? 244 GLU C CD 1 +ATOM 5606 O OE1 . GLU C 1 244 ? -14.030 -26.757 62.343 1.00 180.09 ? 244 GLU C OE1 1 +ATOM 5607 O OE2 . GLU C 1 244 ? -14.277 -28.933 62.166 1.00 144.77 ? 244 GLU C OE2 1 +ATOM 5608 N N . ARG C 1 245 ? -11.601 -27.972 68.383 1.00 159.24 ? 245 ARG C N 1 +ATOM 5609 C CA . ARG C 1 245 ? -10.356 -28.290 69.087 1.00 153.35 ? 245 ARG C CA 1 +ATOM 5610 C C . ARG C 1 245 ? -10.180 -29.790 69.330 1.00 163.39 ? 245 ARG C C 1 +ATOM 5611 O O . ARG C 1 245 ? -9.058 -30.295 69.269 1.00 113.85 ? 245 ARG C O 1 +ATOM 5612 C CB . ARG C 1 245 ? -10.253 -27.569 70.422 1.00 147.95 ? 245 ARG C CB 1 +ATOM 5613 C CG . ARG C 1 245 ? -8.886 -27.734 71.092 1.00 153.85 ? 245 ARG C CG 1 +ATOM 5614 C CD . ARG C 1 245 ? -8.752 -26.924 72.393 1.00 159.62 ? 245 ARG C CD 1 +ATOM 5615 N NE . ARG C 1 245 ? -8.059 -25.655 72.168 1.00 163.80 ? 245 ARG C NE 1 +ATOM 5616 C CZ . ARG C 1 245 ? -6.755 -25.536 71.914 1.00 171.11 ? 245 ARG C CZ 1 +ATOM 5617 N NH1 . ARG C 1 245 ? -5.983 -26.605 71.831 1.00 154.00 ? 245 ARG C NH1 1 +ATOM 5618 N NH2 . ARG C 1 245 ? -6.216 -24.336 71.721 1.00 198.75 ? 245 ARG C NH2 1 +ATOM 5619 N N . GLN C 1 246 ? -11.277 -30.495 69.618 1.00 182.08 ? 246 GLN C N 1 +ATOM 5620 C CA . GLN C 1 246 ? -11.205 -31.928 69.938 1.00 161.21 ? 246 GLN C CA 1 +ATOM 5621 C C . GLN C 1 246 ? -11.422 -32.786 68.696 1.00 152.47 ? 246 GLN C C 1 +ATOM 5622 O O . GLN C 1 246 ? -11.772 -33.955 68.800 1.00 183.47 ? 246 GLN C O 1 +ATOM 5623 C CB . GLN C 1 246 ? -12.215 -32.306 71.026 1.00 149.73 ? 246 GLN C CB 1 +ATOM 5624 C CG . GLN C 1 246 ? -11.883 -31.776 72.409 1.00 155.49 ? 246 GLN C CG 1 +ATOM 5625 C CD . GLN C 1 246 ? -12.176 -30.292 72.542 1.00 191.85 ? 246 GLN C CD 1 +ATOM 5626 O OE1 . GLN C 1 246 ? -13.235 -29.814 72.118 1.00 200.28 ? 246 GLN C OE1 1 +ATOM 5627 N NE2 . GLN C 1 246 ? -11.252 -29.558 73.157 1.00 202.23 ? 246 GLN C NE2 1 +ATOM 5628 N N . ASN C 1 247 ? -11.202 -32.197 67.525 1.00 147.28 ? 247 ASN C N 1 +ATOM 5629 C CA . ASN C 1 247 ? -11.083 -32.945 66.274 1.00 153.15 ? 247 ASN C CA 1 +ATOM 5630 C C . ASN C 1 247 ? -10.291 -34.250 66.441 1.00 162.19 ? 247 ASN C C 1 +ATOM 5631 O O . ASN C 1 247 ? -9.248 -34.266 67.102 1.00 173.06 ? 247 ASN C O 1 +ATOM 5632 C CB . ASN C 1 247 ? -10.385 -32.077 65.226 1.00 155.47 ? 247 ASN C CB 1 +ATOM 5633 C CG . ASN C 1 247 ? -10.765 -32.454 63.820 1.00 148.66 ? 247 ASN C CG 1 +ATOM 5634 O OD1 . ASN C 1 247 ? -9.951 -32.997 63.060 1.00 136.78 ? 247 ASN C OD1 1 +ATOM 5635 N ND2 . ASN C 1 247 ? -11.997 -32.133 63.447 1.00 140.66 ? 247 ASN C ND2 1 +ATOM 5636 N N . ASP C 1 248 ? -10.776 -35.328 65.823 1.00 164.55 ? 248 ASP C N 1 +ATOM 5637 C CA . ASP C 1 248 ? -10.144 -36.656 65.944 1.00 169.97 ? 248 ASP C CA 1 +ATOM 5638 C C . ASP C 1 248 ? -8.650 -36.605 65.616 1.00 187.83 ? 248 ASP C C 1 +ATOM 5639 O O . ASP C 1 248 ? -7.809 -37.176 66.326 1.00 204.15 ? 248 ASP C O 1 +ATOM 5640 C CB . ASP C 1 248 ? -10.815 -37.665 64.998 1.00 168.88 ? 248 ASP C CB 1 +ATOM 5641 C CG . ASP C 1 248 ? -12.214 -38.051 65.440 1.00 176.95 ? 248 ASP C CG 1 +ATOM 5642 O OD1 . ASP C 1 248 ? -12.446 -38.199 66.657 1.00 190.68 ? 248 ASP C OD1 1 +ATOM 5643 O OD2 . ASP C 1 248 ? -13.082 -38.228 64.559 1.00 159.09 ? 248 ASP C OD2 1 +ATOM 5644 N N . ILE C 1 249 ? -8.334 -35.943 64.508 1.00 189.07 ? 249 ILE C N 1 +ATOM 5645 C CA . ILE C 1 249 ? -6.971 -35.873 64.010 1.00 160.80 ? 249 ILE C CA 1 +ATOM 5646 C C . ILE C 1 249 ? -6.109 -35.072 64.991 1.00 143.84 ? 249 ILE C C 1 +ATOM 5647 O O . ILE C 1 249 ? -5.029 -35.516 65.406 1.00 166.24 ? 249 ILE C O 1 +ATOM 5648 C CB . ILE C 1 249 ? -6.937 -35.231 62.606 1.00 154.96 ? 249 ILE C CB 1 +ATOM 5649 C CG1 . ILE C 1 249 ? -7.714 -36.100 61.601 1.00 139.41 ? 249 ILE C CG1 1 +ATOM 5650 C CG2 . ILE C 1 249 ? -5.501 -35.065 62.135 1.00 169.85 ? 249 ILE C CG2 1 +ATOM 5651 C CD1 . ILE C 1 249 ? -8.157 -35.362 60.355 1.00 134.78 ? 249 ILE C CD1 1 +ATOM 5652 N N . LEU C 1 250 ? -6.607 -33.901 65.379 1.00 119.31 ? 250 LEU C N 1 +ATOM 5653 C CA . LEU C 1 250 ? -5.860 -33.005 66.266 1.00 131.91 ? 250 LEU C CA 1 +ATOM 5654 C C . LEU C 1 250 ? -5.546 -33.644 67.615 1.00 151.83 ? 250 LEU C C 1 +ATOM 5655 O O . LEU C 1 250 ? -4.464 -33.430 68.172 1.00 160.71 ? 250 LEU C O 1 +ATOM 5656 C CB . LEU C 1 250 ? -6.622 -31.696 66.475 1.00 119.92 ? 250 LEU C CB 1 +ATOM 5657 C CG . LEU C 1 250 ? -6.490 -30.672 65.339 1.00 131.45 ? 250 LEU C CG 1 +ATOM 5658 C CD1 . LEU C 1 250 ? -7.490 -29.536 65.466 1.00 116.62 ? 250 LEU C CD1 1 +ATOM 5659 C CD2 . LEU C 1 250 ? -5.075 -30.113 65.305 1.00 151.65 ? 250 LEU C CD2 1 +ATOM 5660 N N . VAL C 1 251 ? -6.493 -34.419 68.140 1.00 170.34 ? 251 VAL C N 1 +ATOM 5661 C CA . VAL C 1 251 ? -6.291 -35.098 69.424 1.00 164.65 ? 251 VAL C CA 1 +ATOM 5662 C C . VAL C 1 251 ? -5.397 -36.326 69.268 1.00 162.65 ? 251 VAL C C 1 +ATOM 5663 O O . VAL C 1 251 ? -4.745 -36.757 70.223 1.00 193.36 ? 251 VAL C O 1 +ATOM 5664 C CB . VAL C 1 251 ? -7.622 -35.504 70.094 1.00 149.80 ? 251 VAL C CB 1 +ATOM 5665 C CG1 . VAL C 1 251 ? -8.531 -34.289 70.258 1.00 139.15 ? 251 VAL C CG1 1 +ATOM 5666 C CG2 . VAL C 1 251 ? -8.316 -36.619 69.320 1.00 145.17 ? 251 VAL C CG2 1 +ATOM 5667 N N . LYS C 1 252 ? -5.364 -36.884 68.062 1.00 134.05 ? 252 LYS C N 1 +ATOM 5668 C CA . LYS C 1 252 ? -4.476 -38.008 67.767 1.00 134.87 ? 252 LYS C CA 1 +ATOM 5669 C C . LYS C 1 252 ? -3.004 -37.561 67.812 1.00 141.64 ? 252 LYS C C 1 +ATOM 5670 O O . LYS C 1 252 ? -2.161 -38.205 68.446 1.00 115.30 ? 252 LYS C O 1 +ATOM 5671 C CB . LYS C 1 252 ? -4.845 -38.597 66.403 1.00 139.06 ? 252 LYS C CB 1 +ATOM 5672 C CG . LYS C 1 252 ? -3.984 -39.762 65.938 1.00 131.86 ? 252 LYS C CG 1 +ATOM 5673 C CD . LYS C 1 252 ? -4.441 -40.228 64.560 1.00 147.33 ? 252 LYS C CD 1 +ATOM 5674 C CE . LYS C 1 252 ? -3.264 -40.411 63.613 1.00 150.48 ? 252 LYS C CE 1 +ATOM 5675 N NZ . LYS C 1 252 ? -3.699 -40.602 62.201 1.00 172.70 ? 252 LYS C NZ 1 +ATOM 5676 N N . TYR C 1 253 ? -2.719 -36.422 67.185 1.00 159.87 ? 253 TYR C N 1 +ATOM 5677 C CA . TYR C 1 253 ? -1.356 -35.880 67.138 1.00 151.73 ? 253 TYR C CA 1 +ATOM 5678 C C . TYR C 1 253 ? -0.989 -35.208 68.448 1.00 141.48 ? 253 TYR C C 1 +ATOM 5679 O O . TYR C 1 253 ? 0.175 -35.225 68.858 1.00 179.80 ? 253 TYR C O 1 +ATOM 5680 C CB . TYR C 1 253 ? -1.192 -34.905 65.960 1.00 153.52 ? 253 TYR C CB 1 +ATOM 5681 C CG . TYR C 1 253 ? -1.159 -35.625 64.623 1.00 150.31 ? 253 TYR C CG 1 +ATOM 5682 C CD1 . TYR C 1 253 ? 0.037 -36.109 64.086 1.00 136.74 ? 253 TYR C CD1 1 +ATOM 5683 C CD2 . TYR C 1 253 ? -2.336 -35.895 63.939 1.00 153.52 ? 253 TYR C CD2 1 +ATOM 5684 C CE1 . TYR C 1 253 ? 0.034 -36.803 62.885 1.00 138.47 ? 253 TYR C CE1 1 +ATOM 5685 C CE2 . TYR C 1 253 ? -2.342 -36.599 62.748 1.00 134.70 ? 253 TYR C CE2 1 +ATOM 5686 C CZ . TYR C 1 253 ? -1.159 -37.056 62.229 1.00 131.92 ? 253 TYR C CZ 1 +ATOM 5687 O OH . TYR C 1 253 ? -1.164 -37.756 61.036 1.00 135.74 ? 253 TYR C OH 1 +ATOM 5688 N N . ARG C 1 254 ? -1.988 -34.634 69.108 1.00 156.09 ? 254 ARG C N 1 +ATOM 5689 C CA . ARG C 1 254 ? -1.826 -34.150 70.481 1.00 166.96 ? 254 ARG C CA 1 +ATOM 5690 C C . ARG C 1 254 ? -1.393 -35.293 71.403 1.00 181.78 ? 254 ARG C C 1 +ATOM 5691 O O . ARG C 1 254 ? -0.528 -35.111 72.267 1.00 187.35 ? 254 ARG C O 1 +ATOM 5692 C CB . ARG C 1 254 ? -3.135 -33.546 71.006 1.00 149.40 ? 254 ARG C CB 1 +ATOM 5693 C CG . ARG C 1 254 ? -3.001 -32.915 72.380 1.00 140.35 ? 254 ARG C CG 1 +ATOM 5694 C CD . ARG C 1 254 ? -4.146 -31.973 72.707 1.00 159.59 ? 254 ARG C CD 1 +ATOM 5695 N NE . ARG C 1 254 ? -4.198 -30.780 71.856 1.00 174.85 ? 254 ARG C NE 1 +ATOM 5696 C CZ . ARG C 1 254 ? -5.107 -30.544 70.910 1.00 165.58 ? 254 ARG C CZ 1 +ATOM 5697 N NH1 . ARG C 1 254 ? -6.059 -31.426 70.646 1.00 164.34 ? 254 ARG C NH1 1 +ATOM 5698 N NH2 . ARG C 1 254 ? -5.067 -29.406 70.226 1.00 156.00 ? 254 ARG C NH2 1 +ATOM 5699 N N . HIS C 1 255 ? -1.982 -36.472 71.188 1.00 210.95 ? 255 HIS C N 1 +ATOM 5700 C CA . HIS C 1 255 ? -1.669 -37.666 71.981 1.00 208.78 ? 255 HIS C CA 1 +ATOM 5701 C C . HIS C 1 255 ? -0.265 -38.205 71.723 1.00 170.34 ? 255 HIS C C 1 +ATOM 5702 O O . HIS C 1 255 ? 0.395 -38.694 72.640 1.00 123.86 ? 255 HIS C O 1 +ATOM 5703 C CB . HIS C 1 255 ? -2.701 -38.777 71.731 1.00 223.21 ? 255 HIS C CB 1 +ATOM 5704 C CG . HIS C 1 255 ? -3.667 -38.972 72.857 1.00 229.56 ? 255 HIS C CG 1 +ATOM 5705 N ND1 . HIS C 1 255 ? -4.701 -38.097 73.111 1.00 229.70 ? 255 HIS C ND1 1 +ATOM 5706 C CD2 . HIS C 1 255 ? -3.751 -39.940 73.801 1.00 230.85 ? 255 HIS C CD2 1 +ATOM 5707 C CE1 . HIS C 1 255 ? -5.380 -38.517 74.165 1.00 238.92 ? 255 HIS C CE1 1 +ATOM 5708 N NE2 . HIS C 1 255 ? -4.823 -39.633 74.603 1.00 231.87 ? 255 HIS C NE2 1 +ATOM 5709 N N . MET C 1 256 ? 0.203 -38.097 70.486 1.00 156.30 ? 256 MET C N 1 +ATOM 5710 C CA . MET C 1 256 ? 1.559 -38.546 70.178 1.00 174.27 ? 256 MET C CA 1 +ATOM 5711 C C . MET C 1 256 ? 2.631 -37.689 70.897 1.00 164.44 ? 256 MET C C 1 +ATOM 5712 O O . MET C 1 256 ? 3.752 -38.160 71.131 1.00 126.43 ? 256 MET C O 1 +ATOM 5713 C CB . MET C 1 256 ? 1.777 -38.590 68.649 1.00 180.54 ? 256 MET C CB 1 +ATOM 5714 C CG . MET C 1 256 ? 0.718 -39.395 67.899 1.00 156.74 ? 256 MET C CG 1 +ATOM 5715 S SD . MET C 1 256 ? 1.177 -39.934 66.237 1.00 149.05 ? 256 MET C SD 1 +ATOM 5716 C CE . MET C 1 256 ? 2.443 -41.146 66.625 1.00 163.12 ? 256 MET C CE 1 +ATOM 5717 N N . SER C 1 257 ? 2.285 -36.438 71.219 1.00 153.25 ? 257 SER C N 1 +ATOM 5718 C CA . SER C 1 257 ? 3.177 -35.522 71.945 1.00 130.28 ? 257 SER C CA 1 +ATOM 5719 C C . SER C 1 257 ? 3.222 -35.850 73.432 1.00 115.07 ? 257 SER C C 1 +ATOM 5720 O O . SER C 1 257 ? 4.046 -36.648 73.861 1.00 122.38 ? 257 SER C O 1 +ATOM 5721 C CB . SER C 1 257 ? 2.718 -34.067 71.771 1.00 144.19 ? 257 SER C CB 1 +ATOM 5722 O OG . SER C 1 257 ? 2.357 -33.784 70.433 1.00 133.00 ? 257 SER C OG 1 +ATOM 5723 N N . LEU D 1 2 ? -1.174 -54.832 41.107 1.00 100.19 ? 2 LEU D N 1 +ATOM 5724 C CA . LEU D 1 2 ? 0.085 -54.759 41.911 1.00 109.70 ? 2 LEU D CA 1 +ATOM 5725 C C . LEU D 1 2 ? 1.303 -54.584 40.983 1.00 124.57 ? 2 LEU D C 1 +ATOM 5726 O O . LEU D 1 2 ? 2.146 -55.502 40.805 1.00 95.99 ? 2 LEU D O 1 +ATOM 5727 C CB . LEU D 1 2 ? 0.243 -55.989 42.818 1.00 126.50 ? 2 LEU D CB 1 +ATOM 5728 C CG . LEU D 1 2 ? -0.822 -56.250 43.912 1.00 148.69 ? 2 LEU D CG 1 +ATOM 5729 C CD1 . LEU D 1 2 ? -0.471 -57.531 44.666 1.00 154.58 ? 2 LEU D CD1 1 +ATOM 5730 C CD2 . LEU D 1 2 ? -1.031 -55.101 44.906 1.00 139.92 ? 2 LEU D CD2 1 +ATOM 5731 N N . THR D 1 3 ? 1.289 -53.435 40.301 1.00 140.38 ? 3 THR D N 1 +ATOM 5732 C CA . THR D 1 3 ? 2.471 -52.844 39.659 1.00 127.20 ? 3 THR D CA 1 +ATOM 5733 C C . THR D 1 3 ? 2.485 -51.313 39.856 1.00 110.17 ? 3 THR D C 1 +ATOM 5734 O O . THR D 1 3 ? 3.420 -50.629 39.459 1.00 105.55 ? 3 THR D O 1 +ATOM 5735 C CB . THR D 1 3 ? 2.520 -53.131 38.144 1.00 118.01 ? 3 THR D CB 1 +ATOM 5736 O OG1 . THR D 1 3 ? 1.471 -52.409 37.479 1.00 97.46 ? 3 THR D OG1 1 +ATOM 5737 C CG2 . THR D 1 3 ? 2.423 -54.639 37.863 1.00 106.42 ? 3 THR D CG2 1 +ATOM 5738 N N . ALA D 1 4 ? 1.431 -50.782 40.459 1.00 107.47 ? 4 ALA D N 1 +ATOM 5739 C CA . ALA D 1 4 ? 1.504 -49.495 41.156 1.00 92.49 ? 4 ALA D CA 1 +ATOM 5740 C C . ALA D 1 4 ? 2.260 -49.694 42.496 1.00 87.18 ? 4 ALA D C 1 +ATOM 5741 O O . ALA D 1 4 ? 2.806 -50.762 42.750 1.00 70.62 ? 4 ALA D O 1 +ATOM 5742 C CB . ALA D 1 4 ? 0.103 -48.942 41.374 1.00 98.67 ? 4 ALA D CB 1 +ATOM 5743 N N . PRO D 1 5 ? 2.326 -48.670 43.351 1.00 92.72 ? 5 PRO D N 1 +ATOM 5744 C CA . PRO D 1 5 ? 3.351 -48.878 44.368 1.00 109.07 ? 5 PRO D CA 1 +ATOM 5745 C C . PRO D 1 5 ? 2.842 -49.701 45.545 1.00 122.73 ? 5 PRO D C 1 +ATOM 5746 O O . PRO D 1 5 ? 1.647 -49.967 45.627 1.00 164.64 ? 5 PRO D O 1 +ATOM 5747 C CB . PRO D 1 5 ? 3.675 -47.455 44.811 1.00 158.90 ? 5 PRO D CB 1 +ATOM 5748 C CG . PRO D 1 5 ? 2.433 -46.646 44.524 1.00 148.25 ? 5 PRO D CG 1 +ATOM 5749 C CD . PRO D 1 5 ? 1.630 -47.374 43.489 1.00 108.89 ? 5 PRO D CD 1 +ATOM 5750 N N . PRO D 1 6 ? 3.748 -50.139 46.438 1.00 123.07 ? 6 PRO D N 1 +ATOM 5751 C CA . PRO D 1 6 ? 3.353 -50.672 47.758 1.00 126.13 ? 6 PRO D CA 1 +ATOM 5752 C C . PRO D 1 6 ? 2.999 -49.576 48.752 1.00 128.62 ? 6 PRO D C 1 +ATOM 5753 O O . PRO D 1 6 ? 3.512 -48.461 48.648 1.00 155.44 ? 6 PRO D O 1 +ATOM 5754 C CB . PRO D 1 6 ? 4.582 -51.456 48.231 1.00 102.31 ? 6 PRO D CB 1 +ATOM 5755 C CG . PRO D 1 6 ? 5.712 -50.988 47.390 1.00 98.76 ? 6 PRO D CG 1 +ATOM 5756 C CD . PRO D 1 6 ? 5.185 -50.282 46.171 1.00 103.18 ? 6 PRO D CD 1 +ATOM 5757 N N . LYS D 1 7 ? 2.118 -49.881 49.700 1.00 128.11 ? 7 LYS D N 1 +ATOM 5758 C CA . LYS D 1 7 ? 1.633 -48.858 50.628 1.00 150.88 ? 7 LYS D CA 1 +ATOM 5759 C C . LYS D 1 7 ? 2.416 -48.858 51.939 1.00 146.22 ? 7 LYS D C 1 +ATOM 5760 O O . LYS D 1 7 ? 3.213 -49.784 52.202 1.00 96.55 ? 7 LYS D O 1 +ATOM 5761 C CB . LYS D 1 7 ? 0.120 -48.989 50.865 1.00 157.21 ? 7 LYS D CB 1 +ATOM 5762 C CG . LYS D 1 7 ? -0.683 -48.490 49.621 1.00 166.70 ? 7 LYS D CG 1 +ATOM 5763 C CD . LYS D 1 7 ? -0.658 -46.960 49.486 1.00 172.15 ? 7 LYS D CD 1 +ATOM 5764 C CE . LYS D 1 7 ? -0.871 -46.525 48.038 1.00 165.36 ? 7 LYS D CE 1 +ATOM 5765 N NZ . LYS D 1 7 ? -1.488 -45.172 47.937 1.00 169.59 ? 7 LYS D NZ 1 +ATOM 5766 N N . GLU D 1 8 ? 2.196 -47.798 52.730 1.00 151.29 ? 8 GLU D N 1 +ATOM 5767 C CA . GLU D 1 8 ? 3.017 -47.500 53.909 1.00 142.12 ? 8 GLU D CA 1 +ATOM 5768 C C . GLU D 1 8 ? 2.904 -48.573 54.993 1.00 125.15 ? 8 GLU D C 1 +ATOM 5769 O O . GLU D 1 8 ? 1.841 -48.820 55.528 1.00 103.81 ? 8 GLU D O 1 +ATOM 5770 C CB . GLU D 1 8 ? 2.712 -46.088 54.502 1.00 127.74 ? 8 GLU D CB 1 +ATOM 5771 C CG . GLU D 1 8 ? 1.511 -45.934 55.413 1.00 135.77 ? 8 GLU D CG 1 +ATOM 5772 C CD . GLU D 1 8 ? 1.466 -44.570 56.104 1.00 146.60 ? 8 GLU D CD 1 +ATOM 5773 O OE1 . GLU D 1 8 ? 2.439 -44.192 56.790 1.00 180.11 ? 8 GLU D OE1 1 +ATOM 5774 O OE2 . GLU D 1 8 ? 0.441 -43.877 56.022 1.00 134.68 ? 8 GLU D OE2 1 +ATOM 5775 N N . ALA D 1 9 ? 4.024 -49.223 55.281 1.00 121.43 ? 9 ALA D N 1 +ATOM 5776 C CA . ALA D 1 9 ? 4.137 -50.145 56.397 1.00 93.70 ? 9 ALA D CA 1 +ATOM 5777 C C . ALA D 1 9 ? 4.710 -49.404 57.617 1.00 108.77 ? 9 ALA D C 1 +ATOM 5778 O O . ALA D 1 9 ? 5.870 -48.986 57.612 1.00 127.75 ? 9 ALA D O 1 +ATOM 5779 C CB . ALA D 1 9 ? 5.037 -51.303 56.002 1.00 77.72 ? 9 ALA D CB 1 +ATOM 5780 N N . ALA D 1 10 ? 3.890 -49.280 58.660 1.00 108.15 ? 10 ALA D N 1 +ATOM 5781 C CA . ALA D 1 10 ? 4.177 -48.470 59.862 1.00 108.93 ? 10 ALA D CA 1 +ATOM 5782 C C . ALA D 1 10 ? 3.817 -47.014 59.612 1.00 108.67 ? 10 ALA D C 1 +ATOM 5783 O O . ALA D 1 10 ? 3.696 -46.581 58.468 1.00 94.32 ? 10 ALA D O 1 +ATOM 5784 C CB . ALA D 1 10 ? 5.626 -48.594 60.328 1.00 104.44 ? 10 ALA D CB 1 +ATOM 5785 N N . ARG D 1 11 ? 3.593 -46.278 60.695 1.00 120.25 ? 11 ARG D N 1 +ATOM 5786 C CA . ARG D 1 11 ? 3.177 -44.867 60.618 1.00 132.26 ? 11 ARG D CA 1 +ATOM 5787 C C . ARG D 1 11 ? 4.378 -43.977 60.915 1.00 131.68 ? 11 ARG D C 1 +ATOM 5788 O O . ARG D 1 11 ? 5.279 -44.389 61.634 1.00 102.37 ? 11 ARG D O 1 +ATOM 5789 C CB . ARG D 1 11 ? 2.070 -44.563 61.644 1.00 143.07 ? 11 ARG D CB 1 +ATOM 5790 C CG . ARG D 1 11 ? 2.505 -44.674 63.100 1.00 151.89 ? 11 ARG D CG 1 +ATOM 5791 C CD . ARG D 1 11 ? 1.335 -44.986 64.028 1.00 143.73 ? 11 ARG D CD 1 +ATOM 5792 N NE . ARG D 1 11 ? 1.507 -46.277 64.695 1.00 179.44 ? 11 ARG D NE 1 +ATOM 5793 C CZ . ARG D 1 11 ? 0.676 -46.756 65.617 1.00 184.89 ? 11 ARG D CZ 1 +ATOM 5794 N NH1 . ARG D 1 11 ? -0.397 -46.060 65.960 1.00 211.46 ? 11 ARG D NH1 1 +ATOM 5795 N NH2 . ARG D 1 11 ? 0.904 -47.937 66.185 1.00 145.14 ? 11 ARG D NH2 1 +ATOM 5796 N N . PRO D 1 12 ? 4.395 -42.750 60.367 1.00 119.02 ? 12 PRO D N 1 +ATOM 5797 C CA . PRO D 1 12 ? 5.377 -41.797 60.843 1.00 99.04 ? 12 PRO D CA 1 +ATOM 5798 C C . PRO D 1 12 ? 5.063 -41.451 62.291 1.00 97.97 ? 12 PRO D C 1 +ATOM 5799 O O . PRO D 1 12 ? 4.000 -40.888 62.587 1.00 103.62 ? 12 PRO D O 1 +ATOM 5800 C CB . PRO D 1 12 ? 5.184 -40.579 59.924 1.00 85.45 ? 12 PRO D CB 1 +ATOM 5801 C CG . PRO D 1 12 ? 4.368 -41.051 58.786 1.00 95.38 ? 12 PRO D CG 1 +ATOM 5802 C CD . PRO D 1 12 ? 3.527 -42.174 59.330 1.00 116.34 ? 12 PRO D CD 1 +ATOM 5803 N N . THR D 1 13 ? 5.948 -41.846 63.193 1.00 77.14 ? 13 THR D N 1 +ATOM 5804 C CA . THR D 1 13 ? 5.896 -41.353 64.559 1.00 94.02 ? 13 THR D CA 1 +ATOM 5805 C C . THR D 1 13 ? 6.774 -40.116 64.708 1.00 92.03 ? 13 THR D C 1 +ATOM 5806 O O . THR D 1 13 ? 7.676 -39.904 63.890 1.00 139.89 ? 13 THR D O 1 +ATOM 5807 C CB . THR D 1 13 ? 6.382 -42.439 65.521 1.00 103.05 ? 13 THR D CB 1 +ATOM 5808 O OG1 . THR D 1 13 ? 6.122 -42.027 66.871 1.00 112.00 ? 13 THR D OG1 1 +ATOM 5809 C CG2 . THR D 1 13 ? 7.904 -42.759 65.308 1.00 83.50 ? 13 THR D CG2 1 +ATOM 5810 N N . LEU D 1 14 ? 6.563 -39.310 65.744 1.00 72.29 ? 14 LEU D N 1 +ATOM 5811 C CA . LEU D 1 14 ? 7.586 -38.314 66.039 1.00 64.88 ? 14 LEU D CA 1 +ATOM 5812 C C . LEU D 1 14 ? 8.818 -39.013 66.660 1.00 54.24 ? 14 LEU D C 1 +ATOM 5813 O O . LEU D 1 14 ? 8.746 -40.135 67.092 1.00 41.23 ? 14 LEU D O 1 +ATOM 5814 C CB . LEU D 1 14 ? 7.056 -37.132 66.856 1.00 75.39 ? 14 LEU D CB 1 +ATOM 5815 C CG . LEU D 1 14 ? 6.346 -37.416 68.159 1.00 97.07 ? 14 LEU D CG 1 +ATOM 5816 C CD1 . LEU D 1 14 ? 6.605 -36.305 69.176 1.00 93.69 ? 14 LEU D CD1 1 +ATOM 5817 C CD2 . LEU D 1 14 ? 4.870 -37.536 67.878 1.00 103.26 ? 14 LEU D CD2 1 +ATOM 5818 N N . MET D 1 15 ? 9.977 -38.389 66.598 1.00 69.58 ? 15 MET D N 1 +ATOM 5819 C CA . MET D 1 15 ? 11.244 -39.141 66.597 1.00 92.18 ? 15 MET D CA 1 +ATOM 5820 C C . MET D 1 15 ? 11.518 -39.763 67.961 1.00 79.48 ? 15 MET D C 1 +ATOM 5821 O O . MET D 1 15 ? 11.586 -39.050 68.962 1.00 75.99 ? 15 MET D O 1 +ATOM 5822 C CB . MET D 1 15 ? 12.433 -38.246 66.133 1.00 124.63 ? 15 MET D CB 1 +ATOM 5823 C CG . MET D 1 15 ? 13.551 -39.017 65.425 1.00 128.03 ? 15 MET D CG 1 +ATOM 5824 S SD . MET D 1 15 ? 15.269 -38.466 65.565 1.00 121.12 ? 15 MET D SD 1 +ATOM 5825 C CE . MET D 1 15 ? 15.320 -37.546 67.111 1.00 133.50 ? 15 MET D CE 1 +ATOM 5826 N N . PRO D 1 16 ? 11.731 -41.087 67.989 1.00 93.62 ? 16 PRO D N 1 +ATOM 5827 C CA . PRO D 1 16 ? 11.862 -41.887 69.213 1.00 114.32 ? 16 PRO D CA 1 +ATOM 5828 C C . PRO D 1 16 ? 13.075 -41.561 70.097 1.00 102.47 ? 16 PRO D C 1 +ATOM 5829 O O . PRO D 1 16 ? 14.091 -42.246 70.056 1.00 68.81 ? 16 PRO D O 1 +ATOM 5830 C CB . PRO D 1 16 ? 11.953 -43.326 68.685 1.00 115.79 ? 16 PRO D CB 1 +ATOM 5831 C CG . PRO D 1 16 ? 12.468 -43.185 67.306 1.00 115.03 ? 16 PRO D CG 1 +ATOM 5832 C CD . PRO D 1 16 ? 11.843 -41.924 66.786 1.00 107.60 ? 16 PRO D CD 1 +ATOM 5833 N N . ARG D 1 17 ? 12.942 -40.510 70.901 1.00 116.49 ? 17 ARG D N 1 +ATOM 5834 C CA . ARG D 1 17 ? 13.956 -40.149 71.889 1.00 117.72 ? 17 ARG D CA 1 +ATOM 5835 C C . ARG D 1 17 ? 13.665 -40.877 73.194 1.00 116.32 ? 17 ARG D C 1 +ATOM 5836 O O . ARG D 1 17 ? 12.511 -41.116 73.506 1.00 129.55 ? 17 ARG D O 1 +ATOM 5837 C CB . ARG D 1 17 ? 13.944 -38.633 72.114 1.00 130.21 ? 17 ARG D CB 1 +ATOM 5838 C CG . ARG D 1 17 ? 14.822 -37.868 71.138 1.00 154.51 ? 17 ARG D CG 1 +ATOM 5839 C CD . ARG D 1 17 ? 14.500 -36.380 71.080 1.00 153.11 ? 17 ARG D CD 1 +ATOM 5840 N NE . ARG D 1 17 ? 13.305 -36.110 70.286 1.00 156.37 ? 17 ARG D NE 1 +ATOM 5841 C CZ . ARG D 1 17 ? 12.752 -34.908 70.165 1.00 187.14 ? 17 ARG D CZ 1 +ATOM 5842 N NH1 . ARG D 1 17 ? 13.306 -33.865 70.777 1.00 200.46 ? 17 ARG D NH1 1 +ATOM 5843 N NH2 . ARG D 1 17 ? 11.660 -34.745 69.424 1.00 171.24 ? 17 ARG D NH2 1 +ATOM 5844 N N . ALA D 1 18 ? 14.701 -41.254 73.940 1.00 151.97 ? 18 ALA D N 1 +ATOM 5845 C CA . ALA D 1 18 ? 14.513 -42.048 75.168 1.00 146.95 ? 18 ALA D CA 1 +ATOM 5846 C C . ALA D 1 18 ? 14.887 -41.289 76.450 1.00 143.67 ? 18 ALA D C 1 +ATOM 5847 O O . ALA D 1 18 ? 14.281 -40.260 76.759 1.00 99.36 ? 18 ALA D O 1 +ATOM 5848 C CB . ALA D 1 18 ? 15.260 -43.377 75.077 1.00 140.72 ? 18 ALA D CB 1 +ATOM 5849 N N . GLN D 1 19 ? 15.877 -41.796 77.190 1.00 147.47 ? 19 GLN D N 1 +ATOM 5850 C CA . GLN D 1 19 ? 16.047 -41.418 78.597 1.00 157.42 ? 19 GLN D CA 1 +ATOM 5851 C C . GLN D 1 19 ? 16.541 -39.981 78.744 1.00 146.19 ? 19 GLN D C 1 +ATOM 5852 O O . GLN D 1 19 ? 15.995 -39.181 79.519 1.00 114.98 ? 19 GLN D O 1 +ATOM 5853 C CB . GLN D 1 19 ? 17.022 -42.379 79.291 1.00 150.82 ? 19 GLN D CB 1 +ATOM 5854 C CG . GLN D 1 19 ? 17.151 -42.164 80.792 1.00 164.65 ? 19 GLN D CG 1 +ATOM 5855 C CD . GLN D 1 19 ? 15.809 -42.203 81.505 1.00 179.98 ? 19 GLN D CD 1 +ATOM 5856 O OE1 . GLN D 1 19 ? 15.158 -43.243 81.571 1.00 187.64 ? 19 GLN D OE1 1 +ATOM 5857 N NE2 . GLN D 1 19 ? 15.379 -41.056 82.024 1.00 198.93 ? 19 GLN D NE2 1 +ATOM 5858 N N . SER D 1 20 ? 17.613 -39.688 78.019 1.00 143.38 ? 20 SER D N 1 +ATOM 5859 C CA . SER D 1 20 ? 18.153 -38.350 77.924 1.00 131.39 ? 20 SER D CA 1 +ATOM 5860 C C . SER D 1 20 ? 17.022 -37.324 77.779 1.00 123.56 ? 20 SER D C 1 +ATOM 5861 O O . SER D 1 20 ? 16.992 -36.317 78.494 1.00 96.83 ? 20 SER D O 1 +ATOM 5862 C CB . SER D 1 20 ? 19.116 -38.283 76.726 1.00 146.00 ? 20 SER D CB 1 +ATOM 5863 O OG . SER D 1 20 ? 20.068 -39.338 76.779 1.00 136.41 ? 20 SER D OG 1 +ATOM 5864 N N . TYR D 1 21 ? 16.121 -37.572 76.826 1.00 134.52 ? 21 TYR D N 1 +ATOM 5865 C CA . TYR D 1 21 ? 14.975 -36.690 76.568 1.00 155.28 ? 21 TYR D CA 1 +ATOM 5866 C C . TYR D 1 21 ? 14.100 -36.498 77.808 1.00 153.20 ? 21 TYR D C 1 +ATOM 5867 O O . TYR D 1 21 ? 13.753 -35.366 78.169 1.00 141.48 ? 21 TYR D O 1 +ATOM 5868 C CB . TYR D 1 21 ? 14.120 -37.257 75.435 1.00 160.94 ? 21 TYR D CB 1 +ATOM 5869 C CG . TYR D 1 21 ? 12.927 -36.394 75.097 1.00 159.31 ? 21 TYR D CG 1 +ATOM 5870 C CD1 . TYR D 1 21 ? 13.087 -35.225 74.374 1.00 162.34 ? 21 TYR D CD1 1 +ATOM 5871 C CD2 . TYR D 1 21 ? 11.642 -36.734 75.530 1.00 124.20 ? 21 TYR D CD2 1 +ATOM 5872 C CE1 . TYR D 1 21 ? 11.998 -34.436 74.069 1.00 163.60 ? 21 TYR D CE1 1 +ATOM 5873 C CE2 . TYR D 1 21 ? 10.548 -35.955 75.218 1.00 91.80 ? 21 TYR D CE2 1 +ATOM 5874 C CZ . TYR D 1 21 ? 10.730 -34.812 74.493 1.00 99.71 ? 21 TYR D CZ 1 +ATOM 5875 O OH . TYR D 1 21 ? 9.682 -34.002 74.145 1.00 79.33 ? 21 TYR D OH 1 +ATOM 5876 N N . LYS D 1 22 ? 13.755 -37.607 78.452 1.00 135.91 ? 22 LYS D N 1 +ATOM 5877 C CA . LYS D 1 22 ? 12.885 -37.573 79.614 1.00 145.33 ? 22 LYS D CA 1 +ATOM 5878 C C . LYS D 1 22 ? 13.485 -36.746 80.743 1.00 139.82 ? 22 LYS D C 1 +ATOM 5879 O O . LYS D 1 22 ? 12.774 -36.013 81.441 1.00 124.35 ? 22 LYS D O 1 +ATOM 5880 C CB . LYS D 1 22 ? 12.601 -39.001 80.105 1.00 181.42 ? 22 LYS D CB 1 +ATOM 5881 C CG . LYS D 1 22 ? 11.391 -39.668 79.449 1.00 221.02 ? 22 LYS D CG 1 +ATOM 5882 C CD . LYS D 1 22 ? 10.140 -39.627 80.317 1.00 209.83 ? 22 LYS D CD 1 +ATOM 5883 C CE . LYS D 1 22 ? 8.799 -39.600 79.745 1.00 188.16 ? 22 LYS D CE 1 +ATOM 5884 N NZ . LYS D 1 22 ? 8.109 -40.874 80.023 1.00 192.42 ? 22 LYS D NZ 1 +ATOM 5885 N N . ASP D 1 23 ? 14.791 -36.898 80.944 1.00 141.05 ? 23 ASP D N 1 +ATOM 5886 C CA . ASP D 1 23 ? 15.517 -36.095 81.927 1.00 135.55 ? 23 ASP D CA 1 +ATOM 5887 C C . ASP D 1 23 ? 15.485 -34.625 81.526 1.00 122.27 ? 23 ASP D C 1 +ATOM 5888 O O . ASP D 1 23 ? 15.265 -33.742 82.360 1.00 113.37 ? 23 ASP D O 1 +ATOM 5889 C CB . ASP D 1 23 ? 16.978 -36.571 82.041 1.00 125.51 ? 23 ASP D CB 1 +ATOM 5890 C CG . ASP D 1 23 ? 17.094 -37.928 82.669 1.00 127.28 ? 23 ASP D CG 1 +ATOM 5891 O OD1 . ASP D 1 23 ? 16.347 -38.190 83.640 1.00 138.21 ? 23 ASP D OD1 1 +ATOM 5892 O OD2 . ASP D 1 23 ? 17.901 -38.748 82.180 1.00 129.64 ? 23 ASP D OD2 1 +ATOM 5893 N N . LEU D 1 24 ? 15.747 -34.378 80.247 1.00 118.88 ? 24 LEU D N 1 +ATOM 5894 C CA . LEU D 1 24 ? 15.920 -33.025 79.721 1.00 147.50 ? 24 LEU D CA 1 +ATOM 5895 C C . LEU D 1 24 ? 14.626 -32.216 79.815 1.00 142.31 ? 24 LEU D C 1 +ATOM 5896 O O . LEU D 1 24 ? 14.659 -30.994 80.061 1.00 130.54 ? 24 LEU D O 1 +ATOM 5897 C CB . LEU D 1 24 ? 16.385 -33.096 78.257 1.00 169.86 ? 24 LEU D CB 1 +ATOM 5898 C CG . LEU D 1 24 ? 16.620 -31.776 77.505 1.00 160.62 ? 24 LEU D CG 1 +ATOM 5899 C CD1 . LEU D 1 24 ? 18.029 -31.249 77.749 1.00 143.88 ? 24 LEU D CD1 1 +ATOM 5900 C CD2 . LEU D 1 24 ? 16.369 -31.971 76.018 1.00 145.23 ? 24 LEU D CD2 1 +ATOM 5901 N N . THR D 1 25 ? 13.494 -32.898 79.627 1.00 143.67 ? 25 THR D N 1 +ATOM 5902 C CA . THR D 1 25 ? 12.179 -32.240 79.644 1.00 156.04 ? 25 THR D CA 1 +ATOM 5903 C C . THR D 1 25 ? 11.704 -31.902 81.057 1.00 167.90 ? 25 THR D C 1 +ATOM 5904 O O . THR D 1 25 ? 11.298 -30.763 81.330 1.00 136.96 ? 25 THR D O 1 +ATOM 5905 C CB . THR D 1 25 ? 11.109 -33.111 78.968 1.00 136.96 ? 25 THR D CB 1 +ATOM 5906 O OG1 . THR D 1 25 ? 11.219 -34.458 79.436 1.00 109.49 ? 25 THR D OG1 1 +ATOM 5907 C CG2 . THR D 1 25 ? 11.289 -33.087 77.467 1.00 141.77 ? 25 THR D CG2 1 +ATOM 5908 N N . HIS D 1 26 ? 11.845 -32.869 81.963 1.00 172.57 ? 26 HIS D N 1 +ATOM 5909 C CA . HIS D 1 26 ? 11.432 -32.705 83.357 1.00 167.13 ? 26 HIS D CA 1 +ATOM 5910 C C . HIS D 1 26 ? 12.519 -32.028 84.216 1.00 154.68 ? 26 HIS D C 1 +ATOM 5911 O O . HIS D 1 26 ? 12.686 -32.338 85.388 1.00 151.45 ? 26 HIS D O 1 +ATOM 5912 C CB . HIS D 1 26 ? 11.033 -34.070 83.936 1.00 170.15 ? 26 HIS D CB 1 +ATOM 5913 C CG . HIS D 1 26 ? 9.851 -34.688 83.242 1.00 156.10 ? 26 HIS D CG 1 +ATOM 5914 N ND1 . HIS D 1 26 ? 9.913 -35.167 81.950 1.00 155.60 ? 26 HIS D ND1 1 +ATOM 5915 C CD2 . HIS D 1 26 ? 8.569 -34.868 83.645 1.00 144.18 ? 26 HIS D CD2 1 +ATOM 5916 C CE1 . HIS D 1 26 ? 8.733 -35.651 81.602 1.00 136.67 ? 26 HIS D CE1 1 +ATOM 5917 N NE2 . HIS D 1 26 ? 7.893 -35.458 82.603 1.00 123.91 ? 26 HIS D NE2 1 +ATOM 5918 N N . LEU D 1 27 ? 13.230 -31.068 83.637 1.00 156.91 ? 27 LEU D N 1 +ATOM 5919 C CA . LEU D 1 27 ? 14.187 -30.266 84.392 1.00 136.69 ? 27 LEU D CA 1 +ATOM 5920 C C . LEU D 1 27 ? 13.500 -29.044 84.993 1.00 131.32 ? 27 LEU D C 1 +ATOM 5921 O O . LEU D 1 27 ? 12.699 -28.376 84.329 1.00 103.02 ? 27 LEU D O 1 +ATOM 5922 C CB . LEU D 1 27 ? 15.331 -29.797 83.495 1.00 159.56 ? 27 LEU D CB 1 +ATOM 5923 C CG . LEU D 1 27 ? 16.504 -30.769 83.371 1.00 175.13 ? 27 LEU D CG 1 +ATOM 5924 C CD1 . LEU D 1 27 ? 17.421 -30.365 82.228 1.00 178.06 ? 27 LEU D CD1 1 +ATOM 5925 C CD2 . LEU D 1 27 ? 17.283 -30.850 84.676 1.00 182.05 ? 27 LEU D CD2 1 +ATOM 5926 N N . PRO D 1 28 ? 13.813 -28.742 86.264 1.00 129.50 ? 28 PRO D N 1 +ATOM 5927 C CA . PRO D 1 28 ? 13.172 -27.616 86.969 1.00 140.99 ? 28 PRO D CA 1 +ATOM 5928 C C . PRO D 1 28 ? 13.471 -26.305 86.271 1.00 118.24 ? 28 PRO D C 1 +ATOM 5929 O O . PRO D 1 28 ? 14.620 -26.033 86.001 1.00 139.04 ? 28 PRO D O 1 +ATOM 5930 C CB . PRO D 1 28 ? 13.828 -27.651 88.360 1.00 134.71 ? 28 PRO D CB 1 +ATOM 5931 C CG . PRO D 1 28 ? 15.114 -28.394 88.160 1.00 111.07 ? 28 PRO D CG 1 +ATOM 5932 C CD . PRO D 1 28 ? 14.823 -29.412 87.102 1.00 110.07 ? 28 PRO D CD 1 +ATOM 5933 N N . ALA D 1 29 ? 12.446 -25.503 86.007 1.00 124.64 ? 29 ALA D N 1 +ATOM 5934 C CA . ALA D 1 29 ? 12.590 -24.341 85.141 1.00 125.01 ? 29 ALA D CA 1 +ATOM 5935 C C . ALA D 1 29 ? 13.380 -23.191 85.809 1.00 134.34 ? 29 ALA D C 1 +ATOM 5936 O O . ALA D 1 29 ? 13.344 -23.019 87.032 1.00 124.30 ? 29 ALA D O 1 +ATOM 5937 C CB . ALA D 1 29 ? 11.221 -23.863 84.663 1.00 115.35 ? 29 ALA D CB 1 +ATOM 5938 N N . PRO D 1 30 ? 14.143 -22.429 85.003 1.00 146.16 ? 30 PRO D N 1 +ATOM 5939 C CA . PRO D 1 30 ? 14.880 -21.252 85.474 1.00 146.85 ? 30 PRO D CA 1 +ATOM 5940 C C . PRO D 1 30 ? 13.961 -20.042 85.698 1.00 134.59 ? 30 PRO D C 1 +ATOM 5941 O O . PRO D 1 30 ? 12.772 -20.108 85.364 1.00 92.99 ? 30 PRO D O 1 +ATOM 5942 C CB . PRO D 1 30 ? 15.826 -20.961 84.316 1.00 146.05 ? 30 PRO D CB 1 +ATOM 5943 C CG . PRO D 1 30 ? 15.095 -21.437 83.106 1.00 138.34 ? 30 PRO D CG 1 +ATOM 5944 C CD . PRO D 1 30 ? 14.263 -22.605 83.542 1.00 144.99 ? 30 PRO D CD 1 +ATOM 5945 N N . THR D 1 31 ? 14.526 -18.936 86.197 1.00 125.17 ? 31 THR D N 1 +ATOM 5946 C CA . THR D 1 31 ? 13.743 -17.714 86.474 1.00 140.73 ? 31 THR D CA 1 +ATOM 5947 C C . THR D 1 31 ? 13.235 -17.038 85.198 1.00 134.43 ? 31 THR D C 1 +ATOM 5948 O O . THR D 1 31 ? 12.211 -16.367 85.208 1.00 129.66 ? 31 THR D O 1 +ATOM 5949 C CB . THR D 1 31 ? 14.523 -16.670 87.320 1.00 136.93 ? 31 THR D CB 1 +ATOM 5950 O OG1 . THR D 1 31 ? 15.787 -16.383 86.720 1.00 129.33 ? 31 THR D OG1 1 +ATOM 5951 C CG2 . THR D 1 31 ? 14.742 -17.171 88.742 1.00 142.83 ? 31 THR D CG2 1 +ATOM 5952 N N . GLY D 1 32 ? 13.957 -17.232 84.105 1.00 150.26 ? 32 GLY D N 1 +ATOM 5953 C CA . GLY D 1 32 ? 13.463 -16.886 82.777 1.00 167.77 ? 32 GLY D CA 1 +ATOM 5954 C C . GLY D 1 32 ? 14.214 -17.724 81.759 1.00 166.70 ? 32 GLY D C 1 +ATOM 5955 O O . GLY D 1 32 ? 15.324 -18.178 82.035 1.00 157.30 ? 32 GLY D O 1 +ATOM 5956 N N . LYS D 1 33 ? 13.625 -17.948 80.588 1.00 141.90 ? 33 LYS D N 1 +ATOM 5957 C CA . LYS D 1 33 ? 14.341 -18.665 79.542 1.00 137.17 ? 33 LYS D CA 1 +ATOM 5958 C C . LYS D 1 33 ? 15.518 -17.825 79.023 1.00 154.72 ? 33 LYS D C 1 +ATOM 5959 O O . LYS D 1 33 ? 15.465 -16.596 79.050 1.00 132.03 ? 33 LYS D O 1 +ATOM 5960 C CB . LYS D 1 33 ? 13.414 -19.062 78.396 1.00 132.83 ? 33 LYS D CB 1 +ATOM 5961 C CG . LYS D 1 33 ? 12.762 -20.422 78.573 1.00 121.96 ? 33 LYS D CG 1 +ATOM 5962 C CD . LYS D 1 33 ? 11.724 -20.660 77.493 1.00 129.75 ? 33 LYS D CD 1 +ATOM 5963 C CE . LYS D 1 33 ? 10.664 -21.633 77.971 1.00 135.09 ? 33 LYS D CE 1 +ATOM 5964 N NZ . LYS D 1 33 ? 9.551 -21.749 76.994 1.00 172.19 ? 33 LYS D NZ 1 +ATOM 5965 N N . ILE D 1 34 ? 16.578 -18.494 78.571 1.00 157.95 ? 34 ILE D N 1 +ATOM 5966 C CA . ILE D 1 34 ? 17.777 -17.808 78.113 1.00 130.46 ? 34 ILE D CA 1 +ATOM 5967 C C . ILE D 1 34 ? 17.808 -17.879 76.581 1.00 136.95 ? 34 ILE D C 1 +ATOM 5968 O O . ILE D 1 34 ? 17.337 -18.849 75.968 1.00 163.75 ? 34 ILE D O 1 +ATOM 5969 C CB . ILE D 1 34 ? 19.046 -18.385 78.797 1.00 133.16 ? 34 ILE D CB 1 +ATOM 5970 C CG1 . ILE D 1 34 ? 19.017 -18.085 80.300 1.00 133.30 ? 34 ILE D CG1 1 +ATOM 5971 C CG2 . ILE D 1 34 ? 20.326 -17.787 78.234 1.00 153.22 ? 34 ILE D CG2 1 +ATOM 5972 C CD1 . ILE D 1 34 ? 18.986 -19.325 81.159 1.00 147.34 ? 34 ILE D CD1 1 +ATOM 5973 N N . PHE D 1 35 ? 18.238 -16.780 75.972 1.00 123.93 ? 35 PHE D N 1 +ATOM 5974 C CA . PHE D 1 35 ? 18.330 -16.661 74.524 1.00 103.23 ? 35 PHE D CA 1 +ATOM 5975 C C . PHE D 1 35 ? 19.624 -17.300 74.037 1.00 99.34 ? 35 PHE D C 1 +ATOM 5976 O O . PHE D 1 35 ? 20.711 -16.876 74.455 1.00 133.51 ? 35 PHE D O 1 +ATOM 5977 C CB . PHE D 1 35 ? 18.347 -15.181 74.148 1.00 95.84 ? 35 PHE D CB 1 +ATOM 5978 C CG . PHE D 1 35 ? 16.986 -14.561 74.025 1.00 75.56 ? 35 PHE D CG 1 +ATOM 5979 C CD1 . PHE D 1 35 ? 15.977 -15.199 73.312 1.00 74.18 ? 35 PHE D CD1 1 +ATOM 5980 C CD2 . PHE D 1 35 ? 16.757 -13.284 74.514 1.00 66.49 ? 35 PHE D CD2 1 +ATOM 5981 C CE1 . PHE D 1 35 ? 14.740 -14.597 73.137 1.00 71.24 ? 35 PHE D CE1 1 +ATOM 5982 C CE2 . PHE D 1 35 ? 15.532 -12.673 74.329 1.00 69.46 ? 35 PHE D CE2 1 +ATOM 5983 C CZ . PHE D 1 35 ? 14.514 -13.334 73.648 1.00 69.27 ? 35 PHE D CZ 1 +ATOM 5984 N N . VAL D 1 36 ? 19.528 -18.229 73.087 1.00 69.43 ? 36 VAL D N 1 +ATOM 5985 C CA . VAL D 1 36 ? 20.712 -18.926 72.631 1.00 88.98 ? 36 VAL D CA 1 +ATOM 5986 C C . VAL D 1 36 ? 20.839 -18.973 71.100 1.00 127.15 ? 36 VAL D C 1 +ATOM 5987 O O . VAL D 1 36 ? 19.853 -18.966 70.386 1.00 150.49 ? 36 VAL D O 1 +ATOM 5988 C CB . VAL D 1 36 ? 20.739 -20.348 73.192 1.00 77.92 ? 36 VAL D CB 1 +ATOM 5989 C CG1 . VAL D 1 36 ? 19.751 -21.228 72.448 1.00 75.44 ? 36 VAL D CG1 1 +ATOM 5990 C CG2 . VAL D 1 36 ? 22.147 -20.909 73.105 1.00 85.81 ? 36 VAL D CG2 1 +ATOM 5991 N N . SER D 1 37 ? 22.076 -19.026 70.611 1.00 138.23 ? 37 SER D N 1 +ATOM 5992 C CA . SER D 1 37 ? 22.332 -19.092 69.183 1.00 108.31 ? 37 SER D CA 1 +ATOM 5993 C C . SER D 1 37 ? 23.139 -20.330 68.894 1.00 109.65 ? 37 SER D C 1 +ATOM 5994 O O . SER D 1 37 ? 24.149 -20.596 69.553 1.00 79.83 ? 37 SER D O 1 +ATOM 5995 C CB . SER D 1 37 ? 23.148 -17.894 68.754 1.00 126.26 ? 37 SER D CB 1 +ATOM 5996 O OG . SER D 1 37 ? 22.372 -16.722 68.712 1.00 158.29 ? 37 SER D OG 1 +ATOM 5997 N N . VAL D 1 38 ? 22.731 -21.093 67.894 1.00 103.00 ? 38 VAL D N 1 +ATOM 5998 C CA . VAL D 1 38 ? 23.615 -22.150 67.394 1.00 142.85 ? 38 VAL D CA 1 +ATOM 5999 C C . VAL D 1 38 ? 23.887 -21.902 65.918 1.00 150.34 ? 38 VAL D C 1 +ATOM 6000 O O . VAL D 1 38 ? 22.944 -21.942 65.113 1.00 241.42 ? 38 VAL D O 1 +ATOM 6001 C CB . VAL D 1 38 ? 23.009 -23.568 67.554 1.00 147.37 ? 38 VAL D CB 1 +ATOM 6002 C CG1 . VAL D 1 38 ? 23.946 -24.614 66.962 1.00 128.22 ? 38 VAL D CG1 1 +ATOM 6003 C CG2 . VAL D 1 38 ? 22.725 -23.891 69.010 1.00 158.35 ? 38 VAL D CG2 1 +ATOM 6004 N N . TYR D 1 39 ? 25.167 -21.717 65.565 1.00 103.20 ? 39 TYR D N 1 +ATOM 6005 C CA . TYR D 1 39 ? 25.567 -21.459 64.186 1.00 83.00 ? 39 TYR D CA 1 +ATOM 6006 C C . TYR D 1 39 ? 25.853 -22.794 63.482 1.00 84.02 ? 39 TYR D C 1 +ATOM 6007 O O . TYR D 1 39 ? 25.287 -23.082 62.412 1.00 113.09 ? 39 TYR D O 1 +ATOM 6008 C CB . TYR D 1 39 ? 26.774 -20.503 64.139 1.00 75.42 ? 39 TYR D CB 1 +ATOM 6009 C CG . TYR D 1 39 ? 26.389 -19.026 64.207 1.00 77.45 ? 39 TYR D CG 1 +ATOM 6010 C CD1 . TYR D 1 39 ? 26.010 -18.425 65.400 1.00 76.47 ? 39 TYR D CD1 1 +ATOM 6011 C CD2 . TYR D 1 39 ? 26.386 -18.234 63.078 1.00 96.02 ? 39 TYR D CD2 1 +ATOM 6012 C CE1 . TYR D 1 39 ? 25.595 -17.092 65.454 1.00 69.03 ? 39 TYR D CE1 1 +ATOM 6013 C CE2 . TYR D 1 39 ? 25.991 -16.888 63.126 1.00 106.50 ? 39 TYR D CE2 1 +ATOM 6014 C CZ . TYR D 1 39 ? 25.580 -16.321 64.316 1.00 74.89 ? 39 TYR D CZ 1 +ATOM 6015 O OH . TYR D 1 39 ? 25.184 -14.985 64.334 1.00 43.52 ? 39 TYR D OH 1 +ATOM 6016 N N . ASN D 1 40 ? 26.677 -23.642 64.086 1.00 73.97 ? 40 ASN D N 1 +ATOM 6017 C CA . ASN D 1 40 ? 27.038 -24.908 63.449 1.00 75.00 ? 40 ASN D CA 1 +ATOM 6018 C C . ASN D 1 40 ? 27.774 -25.860 64.362 1.00 84.32 ? 40 ASN D C 1 +ATOM 6019 O O . ASN D 1 40 ? 28.773 -25.487 65.005 1.00 110.55 ? 40 ASN D O 1 +ATOM 6020 C CB . ASN D 1 40 ? 27.912 -24.649 62.211 1.00 94.88 ? 40 ASN D CB 1 +ATOM 6021 C CG . ASN D 1 40 ? 27.955 -25.835 61.268 1.00 106.85 ? 40 ASN D CG 1 +ATOM 6022 O OD1 . ASN D 1 40 ? 29.012 -26.421 61.037 1.00 126.33 ? 40 ASN D OD1 1 +ATOM 6023 N ND2 . ASN D 1 40 ? 26.803 -26.184 60.700 1.00 125.64 ? 40 ASN D ND2 1 +ATOM 6024 N N . ILE D 1 41 ? 27.354 -27.118 64.352 1.00 78.28 ? 41 ILE D N 1 +ATOM 6025 C CA . ILE D 1 41 ? 28.135 -28.201 64.970 1.00 98.54 ? 41 ILE D CA 1 +ATOM 6026 C C . ILE D 1 41 ? 28.581 -29.215 63.907 1.00 80.08 ? 41 ILE D C 1 +ATOM 6027 O O . ILE D 1 41 ? 27.741 -29.851 63.271 1.00 79.47 ? 41 ILE D O 1 +ATOM 6028 C CB . ILE D 1 41 ? 27.320 -28.921 66.073 1.00 103.19 ? 41 ILE D CB 1 +ATOM 6029 C CG1 . ILE D 1 41 ? 27.314 -28.121 67.375 1.00 116.11 ? 41 ILE D CG1 1 +ATOM 6030 C CG2 . ILE D 1 41 ? 27.953 -30.263 66.396 1.00 105.96 ? 41 ILE D CG2 1 +ATOM 6031 C CD1 . ILE D 1 41 ? 26.504 -26.835 67.350 1.00 103.95 ? 41 ILE D CD1 1 +ATOM 6032 N N . GLN D 1 42 ? 29.888 -29.361 63.715 1.00 80.05 ? 42 GLN D N 1 +ATOM 6033 C CA . GLN D 1 42 ? 30.415 -30.106 62.560 1.00 98.75 ? 42 GLN D CA 1 +ATOM 6034 C C . GLN D 1 42 ? 30.635 -31.576 62.853 1.00 85.36 ? 42 GLN D C 1 +ATOM 6035 O O . GLN D 1 42 ? 30.789 -31.974 64.000 1.00 73.97 ? 42 GLN D O 1 +ATOM 6036 C CB . GLN D 1 42 ? 31.756 -29.532 62.095 1.00 129.47 ? 42 GLN D CB 1 +ATOM 6037 C CG . GLN D 1 42 ? 31.683 -28.123 61.548 1.00 147.59 ? 42 GLN D CG 1 +ATOM 6038 C CD . GLN D 1 42 ? 32.521 -27.152 62.358 1.00 167.28 ? 42 GLN D CD 1 +ATOM 6039 O OE1 . GLN D 1 42 ? 33.717 -26.973 62.090 1.00 239.81 ? 42 GLN D OE1 1 +ATOM 6040 N NE2 . GLN D 1 42 ? 31.912 -26.533 63.368 1.00 137.98 ? 42 GLN D NE2 1 +ATOM 6041 N N . ASP D 1 43 ? 30.672 -32.367 61.788 1.00 88.08 ? 43 ASP D N 1 +ATOM 6042 C CA . ASP D 1 43 ? 31.046 -33.781 61.861 1.00 86.09 ? 43 ASP D CA 1 +ATOM 6043 C C . ASP D 1 43 ? 32.534 -33.918 61.849 1.00 61.05 ? 43 ASP D C 1 +ATOM 6044 O O . ASP D 1 43 ? 33.121 -34.412 60.872 1.00 42.56 ? 43 ASP D O 1 +ATOM 6045 C CB . ASP D 1 43 ? 30.448 -34.550 60.665 1.00 140.19 ? 43 ASP D CB 1 +ATOM 6046 C CG . ASP D 1 43 ? 30.637 -36.067 60.782 1.00 153.98 ? 43 ASP D CG 1 +ATOM 6047 O OD1 . ASP D 1 43 ? 30.309 -36.621 61.851 1.00 195.14 ? 43 ASP D OD1 1 +ATOM 6048 O OD2 . ASP D 1 43 ? 31.093 -36.714 59.819 1.00 125.89 ? 43 ASP D OD2 1 +ATOM 6049 N N . GLU D 1 44 ? 33.158 -33.404 62.907 1.00 62.23 ? 44 GLU D N 1 +ATOM 6050 C CA . GLU D 1 44 ? 34.624 -33.371 63.003 1.00 76.96 ? 44 GLU D CA 1 +ATOM 6051 C C . GLU D 1 44 ? 35.232 -34.807 63.136 1.00 79.72 ? 44 GLU D C 1 +ATOM 6052 O O . GLU D 1 44 ? 36.429 -34.951 63.479 1.00 75.65 ? 44 GLU D O 1 +ATOM 6053 C CB . GLU D 1 44 ? 35.094 -32.440 64.167 1.00 69.97 ? 44 GLU D CB 1 +ATOM 6054 C CG . GLU D 1 44 ? 35.279 -30.965 63.791 1.00 102.38 ? 44 GLU D CG 1 +ATOM 6055 C CD . GLU D 1 44 ? 35.699 -30.055 64.963 1.00 126.55 ? 44 GLU D CD 1 +ATOM 6056 O OE1 . GLU D 1 44 ? 36.619 -30.394 65.744 1.00 132.23 ? 44 GLU D OE1 1 +ATOM 6057 O OE2 . GLU D 1 44 ? 35.164 -28.931 65.067 1.00 152.93 ? 44 GLU D OE2 1 +ATOM 6058 N N . THR D 1 45 ? 34.431 -35.833 62.810 1.00 77.74 ? 45 THR D N 1 +ATOM 6059 C CA . THR D 1 45 ? 34.755 -37.226 63.138 1.00 73.60 ? 45 THR D CA 1 +ATOM 6060 C C . THR D 1 45 ? 35.729 -37.870 62.173 1.00 77.65 ? 45 THR D C 1 +ATOM 6061 O O . THR D 1 45 ? 36.685 -38.516 62.608 1.00 93.59 ? 45 THR D O 1 +ATOM 6062 C CB . THR D 1 45 ? 33.511 -38.114 63.258 1.00 57.97 ? 45 THR D CB 1 +ATOM 6063 O OG1 . THR D 1 45 ? 33.884 -39.351 63.864 1.00 96.46 ? 45 THR D OG1 1 +ATOM 6064 C CG2 . THR D 1 45 ? 32.895 -38.391 61.928 1.00 50.69 ? 45 THR D CG2 1 +ATOM 6065 N N . GLY D 1 46 ? 35.585 -37.572 60.892 1.00 93.18 ? 46 GLY D N 1 +ATOM 6066 C CA . GLY D 1 46 ? 36.630 -37.920 59.901 1.00 120.37 ? 46 GLY D CA 1 +ATOM 6067 C C . GLY D 1 46 ? 36.394 -39.301 59.328 1.00 112.09 ? 46 GLY D C 1 +ATOM 6068 O O . GLY D 1 46 ? 37.269 -39.961 58.753 1.00 120.62 ? 46 GLY D O 1 +ATOM 6069 N N . GLN D 1 47 ? 35.179 -39.752 59.447 1.00 93.25 ? 47 GLN D N 1 +ATOM 6070 C CA . GLN D 1 47 ? 34.987 -41.125 59.278 1.00 101.07 ? 47 GLN D CA 1 +ATOM 6071 C C . GLN D 1 47 ? 33.850 -41.417 58.323 1.00 137.79 ? 47 GLN D C 1 +ATOM 6072 O O . GLN D 1 47 ? 32.782 -40.780 58.358 1.00 179.93 ? 47 GLN D O 1 +ATOM 6073 C CB . GLN D 1 47 ? 34.757 -41.718 60.636 1.00 94.55 ? 47 GLN D CB 1 +ATOM 6074 C CG . GLN D 1 47 ? 35.999 -41.699 61.498 1.00 77.24 ? 47 GLN D CG 1 +ATOM 6075 C CD . GLN D 1 47 ? 37.189 -42.267 60.779 1.00 84.61 ? 47 GLN D CD 1 +ATOM 6076 O OE1 . GLN D 1 47 ? 37.304 -43.475 60.588 1.00 70.29 ? 47 GLN D OE1 1 +ATOM 6077 N NE2 . GLN D 1 47 ? 38.117 -41.415 60.437 1.00 111.13 ? 47 GLN D NE2 1 +ATOM 6078 N N . PHE D 1 48 ? 34.073 -42.442 57.512 1.00 142.25 ? 48 PHE D N 1 +ATOM 6079 C CA . PHE D 1 48 ? 33.082 -42.918 56.566 1.00 104.41 ? 48 PHE D CA 1 +ATOM 6080 C C . PHE D 1 48 ? 32.803 -44.399 56.784 1.00 102.29 ? 48 PHE D C 1 +ATOM 6081 O O . PHE D 1 48 ? 33.568 -45.131 57.433 1.00 97.84 ? 48 PHE D O 1 +ATOM 6082 C CB . PHE D 1 48 ? 33.590 -42.689 55.132 1.00 108.77 ? 48 PHE D CB 1 +ATOM 6083 C CG . PHE D 1 48 ? 33.739 -41.265 54.778 1.00 94.89 ? 48 PHE D CG 1 +ATOM 6084 C CD1 . PHE D 1 48 ? 34.816 -40.544 55.248 1.00 77.09 ? 48 PHE D CD1 1 +ATOM 6085 C CD2 . PHE D 1 48 ? 32.738 -40.623 54.085 1.00 97.87 ? 48 PHE D CD2 1 +ATOM 6086 C CE1 . PHE D 1 48 ? 34.877 -39.200 55.052 1.00 79.46 ? 48 PHE D CE1 1 +ATOM 6087 C CE2 . PHE D 1 48 ? 32.778 -39.271 53.900 1.00 93.24 ? 48 PHE D CE2 1 +ATOM 6088 C CZ . PHE D 1 48 ? 33.867 -38.563 54.353 1.00 95.84 ? 48 PHE D CZ 1 +ATOM 6089 N N . LYS D 1 49 ? 31.745 -44.860 56.138 1.00 114.89 ? 49 LYS D N 1 +ATOM 6090 C CA . LYS D 1 49 ? 31.333 -46.249 56.238 1.00 106.09 ? 49 LYS D CA 1 +ATOM 6091 C C . LYS D 1 49 ? 32.237 -47.113 55.370 1.00 99.61 ? 49 LYS D C 1 +ATOM 6092 O O . LYS D 1 49 ? 32.679 -46.693 54.297 1.00 81.08 ? 49 LYS D O 1 +ATOM 6093 C CB . LYS D 1 49 ? 29.848 -46.417 55.856 1.00 95.84 ? 49 LYS D CB 1 +ATOM 6094 C CG . LYS D 1 49 ? 28.916 -45.705 56.832 1.00 99.14 ? 49 LYS D CG 1 +ATOM 6095 C CD . LYS D 1 49 ? 27.422 -45.939 56.666 1.00 97.55 ? 49 LYS D CD 1 +ATOM 6096 C CE . LYS D 1 49 ? 26.716 -45.238 57.835 1.00 100.80 ? 49 LYS D CE 1 +ATOM 6097 N NZ . LYS D 1 49 ? 25.229 -45.370 57.862 1.00 96.50 ? 49 LYS D NZ 1 +ATOM 6098 N N . PRO D 1 50 ? 32.511 -48.329 55.847 1.00 110.58 ? 50 PRO D N 1 +ATOM 6099 C CA . PRO D 1 50 ? 33.326 -49.270 55.106 1.00 110.68 ? 50 PRO D CA 1 +ATOM 6100 C C . PRO D 1 50 ? 32.566 -49.930 53.956 1.00 113.59 ? 50 PRO D C 1 +ATOM 6101 O O . PRO D 1 50 ? 31.313 -49.879 53.901 1.00 154.88 ? 50 PRO D O 1 +ATOM 6102 C CB . PRO D 1 50 ? 33.726 -50.291 56.182 1.00 119.55 ? 50 PRO D CB 1 +ATOM 6103 C CG . PRO D 1 50 ? 32.607 -50.259 57.172 1.00 114.67 ? 50 PRO D CG 1 +ATOM 6104 C CD . PRO D 1 50 ? 32.087 -48.854 57.164 1.00 114.20 ? 50 PRO D CD 1 +ATOM 6105 N N . TYR D 1 51 ? 33.308 -50.592 53.077 1.00 108.70 ? 51 TYR D N 1 +ATOM 6106 C CA . TYR D 1 51 ? 32.694 -51.481 52.112 1.00 109.67 ? 51 TYR D CA 1 +ATOM 6107 C C . TYR D 1 51 ? 31.659 -52.395 52.802 1.00 130.36 ? 51 TYR D C 1 +ATOM 6108 O O . TYR D 1 51 ? 31.937 -52.962 53.859 1.00 123.14 ? 51 TYR D O 1 +ATOM 6109 C CB . TYR D 1 51 ? 33.747 -52.339 51.407 1.00 82.74 ? 51 TYR D CB 1 +ATOM 6110 C CG . TYR D 1 51 ? 33.208 -52.970 50.171 1.00 107.79 ? 51 TYR D CG 1 +ATOM 6111 C CD1 . TYR D 1 51 ? 33.200 -52.267 48.978 1.00 151.45 ? 51 TYR D CD1 1 +ATOM 6112 C CD2 . TYR D 1 51 ? 32.633 -54.251 50.182 1.00 138.05 ? 51 TYR D CD2 1 +ATOM 6113 C CE1 . TYR D 1 51 ? 32.650 -52.810 47.823 1.00 175.78 ? 51 TYR D CE1 1 +ATOM 6114 C CE2 . TYR D 1 51 ? 32.116 -54.829 49.007 1.00 141.89 ? 51 TYR D CE2 1 +ATOM 6115 C CZ . TYR D 1 51 ? 32.104 -54.078 47.839 1.00 155.66 ? 51 TYR D CZ 1 +ATOM 6116 O OH . TYR D 1 51 ? 31.604 -54.557 46.652 1.00 142.27 ? 51 TYR D OH 1 +ATOM 6117 N N . PRO D 1 52 ? 30.451 -52.549 52.210 1.00 148.35 ? 52 PRO D N 1 +ATOM 6118 C CA . PRO D 1 52 ? 30.019 -52.108 50.874 1.00 138.89 ? 52 PRO D CA 1 +ATOM 6119 C C . PRO D 1 52 ? 29.310 -50.758 50.773 1.00 82.70 ? 52 PRO D C 1 +ATOM 6120 O O . PRO D 1 52 ? 28.649 -50.515 49.768 1.00 96.06 ? 52 PRO D O 1 +ATOM 6121 C CB . PRO D 1 52 ? 29.042 -53.218 50.462 1.00 141.09 ? 52 PRO D CB 1 +ATOM 6122 C CG . PRO D 1 52 ? 28.395 -53.616 51.752 1.00 133.01 ? 52 PRO D CG 1 +ATOM 6123 C CD . PRO D 1 52 ? 29.467 -53.478 52.809 1.00 137.37 ? 52 PRO D CD 1 +ATOM 6124 N N . ALA D 1 53 ? 29.392 -49.924 51.795 1.00 53.19 ? 53 ALA D N 1 +ATOM 6125 C CA . ALA D 1 53 ? 28.776 -48.611 51.698 1.00 68.24 ? 53 ALA D CA 1 +ATOM 6126 C C . ALA D 1 53 ? 29.372 -47.824 50.543 1.00 79.50 ? 53 ALA D C 1 +ATOM 6127 O O . ALA D 1 53 ? 30.526 -48.098 50.102 1.00 108.94 ? 53 ALA D O 1 +ATOM 6128 C CB . ALA D 1 53 ? 28.940 -47.841 53.003 1.00 90.27 ? 53 ALA D CB 1 +ATOM 6129 N N . SER D 1 54 ? 28.682 -46.756 50.146 1.00 73.33 ? 54 SER D N 1 +ATOM 6130 C CA . SER D 1 54 ? 29.339 -45.798 49.283 1.00 108.72 ? 54 SER D CA 1 +ATOM 6131 C C . SER D 1 54 ? 30.580 -45.221 49.989 1.00 118.89 ? 54 SER D C 1 +ATOM 6132 O O . SER D 1 54 ? 30.583 -44.950 51.188 1.00 76.02 ? 54 SER D O 1 +ATOM 6133 C CB . SER D 1 54 ? 28.407 -44.672 48.851 1.00 130.78 ? 54 SER D CB 1 +ATOM 6134 O OG . SER D 1 54 ? 29.124 -43.513 48.399 1.00 205.79 ? 54 SER D OG 1 +ATOM 6135 N N . ASN D 1 55 ? 31.653 -45.064 49.213 1.00 98.21 ? 55 ASN D N 1 +ATOM 6136 C CA . ASN D 1 55 ? 32.849 -44.417 49.685 1.00 74.50 ? 55 ASN D CA 1 +ATOM 6137 C C . ASN D 1 55 ? 32.540 -43.093 50.432 1.00 77.55 ? 55 ASN D C 1 +ATOM 6138 O O . ASN D 1 55 ? 33.286 -42.672 51.344 1.00 79.80 ? 55 ASN D O 1 +ATOM 6139 C CB . ASN D 1 55 ? 33.752 -44.130 48.500 1.00 69.33 ? 55 ASN D CB 1 +ATOM 6140 C CG . ASN D 1 55 ? 35.170 -43.841 48.918 1.00 91.95 ? 55 ASN D CG 1 +ATOM 6141 O OD1 . ASN D 1 55 ? 35.604 -44.164 50.013 1.00 126.13 ? 55 ASN D OD1 1 +ATOM 6142 N ND2 . ASN D 1 55 ? 35.906 -43.268 48.018 1.00 101.94 ? 55 ASN D ND2 1 +ATOM 6143 N N . PHE D 1 56 ? 31.440 -42.436 50.034 1.00 60.50 ? 56 PHE D N 1 +ATOM 6144 C CA . PHE D 1 56 ? 31.113 -41.083 50.484 1.00 55.31 ? 56 PHE D CA 1 +ATOM 6145 C C . PHE D 1 56 ? 30.128 -41.108 51.620 1.00 58.97 ? 56 PHE D C 1 +ATOM 6146 O O . PHE D 1 56 ? 29.698 -40.032 52.085 1.00 68.11 ? 56 PHE D O 1 +ATOM 6147 C CB . PHE D 1 56 ? 30.482 -40.253 49.383 1.00 51.13 ? 56 PHE D CB 1 +ATOM 6148 C CG . PHE D 1 56 ? 31.350 -40.061 48.219 1.00 69.26 ? 56 PHE D CG 1 +ATOM 6149 C CD1 . PHE D 1 56 ? 32.569 -39.404 48.317 1.00 85.95 ? 56 PHE D CD1 1 +ATOM 6150 C CD2 . PHE D 1 56 ? 30.991 -40.599 47.007 1.00 116.79 ? 56 PHE D CD2 1 +ATOM 6151 C CE1 . PHE D 1 56 ? 33.417 -39.279 47.215 1.00 107.14 ? 56 PHE D CE1 1 +ATOM 6152 C CE2 . PHE D 1 56 ? 31.815 -40.443 45.894 1.00 158.41 ? 56 PHE D CE2 1 +ATOM 6153 C CZ . PHE D 1 56 ? 33.041 -39.793 46.003 1.00 123.68 ? 56 PHE D CZ 1 +ATOM 6154 N N . SER D 1 57 ? 29.679 -42.288 52.031 1.00 48.60 ? 57 SER D N 1 +ATOM 6155 C CA . SER D 1 57 ? 28.729 -42.323 53.121 1.00 62.10 ? 57 SER D CA 1 +ATOM 6156 C C . SER D 1 57 ? 29.481 -42.020 54.435 1.00 58.90 ? 57 SER D C 1 +ATOM 6157 O O . SER D 1 57 ? 30.308 -42.804 54.892 1.00 62.31 ? 57 SER D O 1 +ATOM 6158 C CB . SER D 1 57 ? 27.993 -43.668 53.154 1.00 81.25 ? 57 SER D CB 1 +ATOM 6159 O OG . SER D 1 57 ? 27.033 -43.726 52.118 1.00 108.01 ? 57 SER D OG 1 +ATOM 6160 N N . THR D 1 58 ? 29.128 -40.921 55.076 1.00 58.18 ? 58 THR D N 1 +ATOM 6161 C CA . THR D 1 58 ? 29.711 -40.583 56.354 1.00 71.16 ? 58 THR D CA 1 +ATOM 6162 C C . THR D 1 58 ? 29.263 -41.547 57.427 1.00 89.90 ? 58 THR D C 1 +ATOM 6163 O O . THR D 1 58 ? 28.137 -42.046 57.456 1.00 114.81 ? 58 THR D O 1 +ATOM 6164 C CB . THR D 1 58 ? 29.295 -39.171 56.787 1.00 68.01 ? 58 THR D CB 1 +ATOM 6165 O OG1 . THR D 1 58 ? 27.859 -39.110 56.936 1.00 41.42 ? 58 THR D OG1 1 +ATOM 6166 C CG2 . THR D 1 58 ? 29.712 -38.221 55.742 1.00 79.55 ? 58 THR D CG2 1 +ATOM 6167 N N . ALA D 1 59 ? 30.091 -41.724 58.414 1.00 97.61 ? 59 ALA D N 1 +ATOM 6168 C CA . ALA D 1 59 ? 29.679 -42.614 59.474 1.00 105.18 ? 59 ALA D CA 1 +ATOM 6169 C C . ALA D 1 59 ? 28.585 -42.019 60.386 1.00 75.02 ? 59 ALA D C 1 +ATOM 6170 O O . ALA D 1 59 ? 27.953 -42.728 61.141 1.00 67.75 ? 59 ALA D O 1 +ATOM 6171 C CB . ALA D 1 59 ? 30.900 -43.040 60.265 1.00 121.34 ? 59 ALA D CB 1 +ATOM 6172 N N . VAL D 1 60 ? 28.476 -40.700 60.390 1.00 69.00 ? 60 VAL D N 1 +ATOM 6173 C CA . VAL D 1 60 ? 27.675 -39.985 61.363 1.00 61.58 ? 60 VAL D CA 1 +ATOM 6174 C C . VAL D 1 60 ? 26.876 -38.958 60.620 1.00 68.06 ? 60 VAL D C 1 +ATOM 6175 O O . VAL D 1 60 ? 27.377 -38.320 59.663 1.00 76.59 ? 60 VAL D O 1 +ATOM 6176 C CB . VAL D 1 60 ? 28.575 -39.233 62.360 1.00 91.28 ? 60 VAL D CB 1 +ATOM 6177 C CG1 . VAL D 1 60 ? 27.758 -38.419 63.362 1.00 84.49 ? 60 VAL D CG1 1 +ATOM 6178 C CG2 . VAL D 1 60 ? 29.496 -40.213 63.095 1.00 133.91 ? 60 VAL D CG2 1 +ATOM 6179 N N . PRO D 1 61 ? 25.629 -38.765 61.033 1.00 77.73 ? 61 PRO D N 1 +ATOM 6180 C CA . PRO D 1 61 ? 24.789 -37.811 60.285 1.00 100.88 ? 61 PRO D CA 1 +ATOM 6181 C C . PRO D 1 61 ? 25.240 -36.371 60.465 1.00 83.43 ? 61 PRO D C 1 +ATOM 6182 O O . PRO D 1 61 ? 25.769 -36.029 61.532 1.00 70.78 ? 61 PRO D O 1 +ATOM 6183 C CB . PRO D 1 61 ? 23.397 -38.004 60.902 1.00 117.18 ? 61 PRO D CB 1 +ATOM 6184 C CG . PRO D 1 61 ? 23.652 -38.642 62.227 1.00 107.73 ? 61 PRO D CG 1 +ATOM 6185 C CD . PRO D 1 61 ? 24.846 -39.529 62.008 1.00 90.09 ? 61 PRO D CD 1 +ATOM 6186 N N . GLN D 1 62 ? 25.033 -35.561 59.427 1.00 71.93 ? 62 GLN D N 1 +ATOM 6187 C CA . GLN D 1 62 ? 25.609 -34.222 59.378 1.00 79.80 ? 62 GLN D CA 1 +ATOM 6188 C C . GLN D 1 62 ? 24.619 -33.274 59.955 1.00 65.72 ? 62 GLN D C 1 +ATOM 6189 O O . GLN D 1 62 ? 24.518 -32.142 59.499 1.00 118.61 ? 62 GLN D O 1 +ATOM 6190 C CB . GLN D 1 62 ? 25.947 -33.791 57.919 1.00 82.66 ? 62 GLN D CB 1 +ATOM 6191 C CG . GLN D 1 62 ? 26.830 -34.769 57.152 1.00 85.02 ? 62 GLN D CG 1 +ATOM 6192 C CD . GLN D 1 62 ? 28.155 -35.021 57.857 1.00 74.48 ? 62 GLN D CD 1 +ATOM 6193 O OE1 . GLN D 1 62 ? 29.056 -34.200 57.801 1.00 53.72 ? 62 GLN D OE1 1 +ATOM 6194 N NE2 . GLN D 1 62 ? 28.261 -36.153 58.550 1.00 67.90 ? 62 GLN D NE2 1 +ATOM 6195 N N . SER D 1 63 ? 23.892 -33.718 60.959 1.00 55.95 ? 63 SER D N 1 +ATOM 6196 C CA . SER D 1 63 ? 22.663 -33.051 61.355 1.00 80.72 ? 63 SER D CA 1 +ATOM 6197 C C . SER D 1 63 ? 22.697 -32.544 62.798 1.00 76.45 ? 63 SER D C 1 +ATOM 6198 O O . SER D 1 63 ? 21.678 -32.151 63.366 1.00 97.89 ? 63 SER D O 1 +ATOM 6199 C CB . SER D 1 63 ? 21.462 -33.999 61.103 1.00 98.55 ? 63 SER D CB 1 +ATOM 6200 O OG . SER D 1 63 ? 21.519 -35.187 61.869 1.00 116.34 ? 63 SER D OG 1 +ATOM 6201 N N . ALA D 1 64 ? 23.872 -32.604 63.394 1.00 70.63 ? 64 ALA D N 1 +ATOM 6202 C CA . ALA D 1 64 ? 24.014 -32.399 64.825 1.00 79.42 ? 64 ALA D CA 1 +ATOM 6203 C C . ALA D 1 64 ? 23.476 -31.038 65.254 1.00 70.68 ? 64 ALA D C 1 +ATOM 6204 O O . ALA D 1 64 ? 22.910 -30.870 66.344 1.00 55.06 ? 64 ALA D O 1 +ATOM 6205 C CB . ALA D 1 64 ? 25.487 -32.560 65.196 1.00 88.35 ? 64 ALA D CB 1 +ATOM 6206 N N . THR D 1 65 ? 23.693 -30.058 64.388 1.00 87.24 ? 65 THR D N 1 +ATOM 6207 C CA . THR D 1 65 ? 23.314 -28.679 64.663 1.00 110.33 ? 65 THR D CA 1 +ATOM 6208 C C . THR D 1 65 ? 21.844 -28.603 65.044 1.00 98.12 ? 65 THR D C 1 +ATOM 6209 O O . THR D 1 65 ? 21.470 -27.950 66.024 1.00 79.33 ? 65 THR D O 1 +ATOM 6210 C CB . THR D 1 65 ? 23.544 -27.821 63.408 1.00 99.48 ? 65 THR D CB 1 +ATOM 6211 O OG1 . THR D 1 65 ? 24.780 -28.222 62.808 1.00 96.74 ? 65 THR D OG1 1 +ATOM 6212 C CG2 . THR D 1 65 ? 23.581 -26.335 63.769 1.00 104.15 ? 65 THR D CG2 1 +ATOM 6213 N N . ALA D 1 66 ? 21.017 -29.243 64.234 1.00 104.52 ? 66 ALA D N 1 +ATOM 6214 C CA . ALA D 1 66 ? 19.584 -29.124 64.396 1.00 113.08 ? 66 ALA D CA 1 +ATOM 6215 C C . ALA D 1 66 ? 19.141 -29.896 65.623 1.00 79.58 ? 66 ALA D C 1 +ATOM 6216 O O . ALA D 1 66 ? 18.217 -29.475 66.330 1.00 70.47 ? 66 ALA D O 1 +ATOM 6217 C CB . ALA D 1 66 ? 18.876 -29.610 63.140 1.00 116.74 ? 66 ALA D CB 1 +ATOM 6218 N N . MET D 1 67 ? 19.855 -30.978 65.905 1.00 87.09 ? 67 MET D N 1 +ATOM 6219 C CA . MET D 1 67 ? 19.575 -31.785 67.086 1.00 118.63 ? 67 MET D CA 1 +ATOM 6220 C C . MET D 1 67 ? 19.863 -30.983 68.354 1.00 123.77 ? 67 MET D C 1 +ATOM 6221 O O . MET D 1 67 ? 19.073 -31.009 69.321 1.00 131.37 ? 67 MET D O 1 +ATOM 6222 C CB . MET D 1 67 ? 20.419 -33.066 67.099 1.00 106.25 ? 67 MET D CB 1 +ATOM 6223 C CG . MET D 1 67 ? 20.042 -34.116 66.065 1.00 102.18 ? 67 MET D CG 1 +ATOM 6224 S SD . MET D 1 67 ? 21.293 -35.414 65.951 1.00 80.37 ? 67 MET D SD 1 +ATOM 6225 C CE . MET D 1 67 ? 20.516 -36.571 64.835 1.00 109.15 ? 67 MET D CE 1 +ATOM 6226 N N . LEU D 1 68 ? 20.957 -30.231 68.326 1.00 96.75 ? 68 LEU D N 1 +ATOM 6227 C CA . LEU D 1 68 ? 21.312 -29.418 69.472 1.00 98.67 ? 68 LEU D CA 1 +ATOM 6228 C C . LEU D 1 68 ? 20.305 -28.316 69.689 1.00 94.95 ? 68 LEU D C 1 +ATOM 6229 O O . LEU D 1 68 ? 19.889 -28.074 70.829 1.00 113.52 ? 68 LEU D O 1 +ATOM 6230 C CB . LEU D 1 68 ? 22.685 -28.785 69.315 1.00 100.39 ? 68 LEU D CB 1 +ATOM 6231 C CG . LEU D 1 68 ? 22.995 -27.727 70.403 1.00 78.53 ? 68 LEU D CG 1 +ATOM 6232 C CD1 . LEU D 1 68 ? 23.124 -28.360 71.770 1.00 68.46 ? 68 LEU D CD1 1 +ATOM 6233 C CD2 . LEU D 1 68 ? 24.258 -26.956 70.077 1.00 90.10 ? 68 LEU D CD2 1 +ATOM 6234 N N . VAL D 1 69 ? 19.908 -27.641 68.613 1.00 99.84 ? 69 VAL D N 1 +ATOM 6235 C CA . VAL D 1 69 ? 18.902 -26.571 68.729 1.00 143.13 ? 69 VAL D CA 1 +ATOM 6236 C C . VAL D 1 69 ? 17.578 -27.112 69.296 1.00 134.45 ? 69 VAL D C 1 +ATOM 6237 O O . VAL D 1 69 ? 16.987 -26.530 70.209 1.00 132.25 ? 69 VAL D O 1 +ATOM 6238 C CB . VAL D 1 69 ? 18.592 -25.900 67.376 1.00 166.86 ? 69 VAL D CB 1 +ATOM 6239 C CG1 . VAL D 1 69 ? 17.432 -24.928 67.535 1.00 180.46 ? 69 VAL D CG1 1 +ATOM 6240 C CG2 . VAL D 1 69 ? 19.803 -25.165 66.823 1.00 156.11 ? 69 VAL D CG2 1 +ATOM 6241 N N . THR D 1 70 ? 17.166 -28.271 68.799 1.00 128.82 ? 70 THR D N 1 +ATOM 6242 C CA . THR D 1 70 ? 15.970 -28.940 69.295 1.00 131.31 ? 70 THR D CA 1 +ATOM 6243 C C . THR D 1 70 ? 16.082 -29.320 70.774 1.00 131.58 ? 70 THR D C 1 +ATOM 6244 O O . THR D 1 70 ? 15.159 -29.080 71.560 1.00 114.09 ? 70 THR D O 1 +ATOM 6245 C CB . THR D 1 70 ? 15.673 -30.198 68.462 1.00 151.70 ? 70 THR D CB 1 +ATOM 6246 O OG1 . THR D 1 70 ? 15.618 -29.819 67.079 1.00 197.59 ? 70 THR D OG1 1 +ATOM 6247 C CG2 . THR D 1 70 ? 14.343 -30.844 68.894 1.00 141.53 ? 70 THR D CG2 1 +ATOM 6248 N N . ALA D 1 71 ? 17.226 -29.887 71.160 1.00 120.17 ? 71 ALA D N 1 +ATOM 6249 C CA . ALA D 1 71 ? 17.461 -30.234 72.561 1.00 132.88 ? 71 ALA D CA 1 +ATOM 6250 C C . ALA D 1 71 ? 17.434 -28.986 73.458 1.00 141.16 ? 71 ALA D C 1 +ATOM 6251 O O . ALA D 1 71 ? 16.848 -28.991 74.552 1.00 156.40 ? 71 ALA D O 1 +ATOM 6252 C CB . ALA D 1 71 ? 18.785 -30.972 72.713 1.00 111.97 ? 71 ALA D CB 1 +ATOM 6253 N N . LEU D 1 72 ? 18.062 -27.913 72.985 1.00 124.18 ? 72 LEU D N 1 +ATOM 6254 C CA . LEU D 1 72 ? 18.049 -26.641 73.715 1.00 103.80 ? 72 LEU D CA 1 +ATOM 6255 C C . LEU D 1 72 ? 16.621 -26.117 73.905 1.00 120.90 ? 72 LEU D C 1 +ATOM 6256 O O . LEU D 1 72 ? 16.363 -25.374 74.852 1.00 111.56 ? 72 LEU D O 1 +ATOM 6257 C CB . LEU D 1 72 ? 18.898 -25.584 73.002 1.00 74.15 ? 72 LEU D CB 1 +ATOM 6258 C CG . LEU D 1 72 ? 20.387 -25.868 72.978 1.00 64.57 ? 72 LEU D CG 1 +ATOM 6259 C CD1 . LEU D 1 72 ? 21.028 -25.019 71.922 1.00 65.87 ? 72 LEU D CD1 1 +ATOM 6260 C CD2 . LEU D 1 72 ? 21.026 -25.589 74.312 1.00 87.90 ? 72 LEU D CD2 1 +ATOM 6261 N N . LYS D 1 73 ? 15.711 -26.480 72.993 1.00 115.20 ? 73 LYS D N 1 +ATOM 6262 C CA . LYS D 1 73 ? 14.326 -26.012 73.083 1.00 103.87 ? 73 LYS D CA 1 +ATOM 6263 C C . LYS D 1 73 ? 13.512 -26.884 73.988 1.00 109.45 ? 73 LYS D C 1 +ATOM 6264 O O . LYS D 1 73 ? 12.790 -26.386 74.848 1.00 117.08 ? 73 LYS D O 1 +ATOM 6265 C CB . LYS D 1 73 ? 13.658 -25.964 71.723 1.00 99.32 ? 73 LYS D CB 1 +ATOM 6266 C CG . LYS D 1 73 ? 12.330 -25.213 71.736 1.00 123.47 ? 73 LYS D CG 1 +ATOM 6267 C CD . LYS D 1 73 ? 11.682 -25.187 70.349 1.00 181.20 ? 73 LYS D CD 1 +ATOM 6268 C CE . LYS D 1 73 ? 10.164 -25.092 70.420 1.00 205.25 ? 73 LYS D CE 1 +ATOM 6269 N NZ . LYS D 1 73 ? 9.631 -23.806 69.883 1.00 226.97 ? 73 LYS D NZ 1 +ATOM 6270 N N . ASP D 1 74 ? 13.659 -28.191 73.822 1.00 124.92 ? 74 ASP D N 1 +ATOM 6271 C CA . ASP D 1 74 ? 12.903 -29.140 74.628 1.00 155.20 ? 74 ASP D CA 1 +ATOM 6272 C C . ASP D 1 74 ? 13.164 -28.983 76.130 1.00 147.12 ? 74 ASP D C 1 +ATOM 6273 O O . ASP D 1 74 ? 12.287 -29.289 76.954 1.00 172.68 ? 74 ASP D O 1 +ATOM 6274 C CB . ASP D 1 74 ? 13.212 -30.578 74.189 1.00 164.73 ? 74 ASP D CB 1 +ATOM 6275 C CG . ASP D 1 74 ? 12.718 -30.882 72.768 1.00 147.93 ? 74 ASP D CG 1 +ATOM 6276 O OD1 . ASP D 1 74 ? 11.676 -30.322 72.338 1.00 131.12 ? 74 ASP D OD1 1 +ATOM 6277 O OD2 . ASP D 1 74 ? 13.303 -31.800 72.151 1.00 98.02 ? 74 ASP D OD2 1 +ATOM 6278 N N . SER D 1 75 ? 14.363 -28.516 76.480 1.00 128.32 ? 75 SER D N 1 +ATOM 6279 C CA . SER D 1 75 ? 14.772 -28.377 77.884 1.00 132.34 ? 75 SER D CA 1 +ATOM 6280 C C . SER D 1 75 ? 13.934 -27.340 78.640 1.00 126.52 ? 75 SER D C 1 +ATOM 6281 O O . SER D 1 75 ? 13.831 -27.409 79.873 1.00 111.25 ? 75 SER D O 1 +ATOM 6282 C CB . SER D 1 75 ? 16.253 -27.986 77.983 1.00 127.82 ? 75 SER D CB 1 +ATOM 6283 O OG . SER D 1 75 ? 16.417 -26.582 77.883 1.00 93.10 ? 75 SER D OG 1 +ATOM 6284 N N . ARG D 1 76 ? 13.368 -26.388 77.894 1.00 107.34 ? 76 ARG D N 1 +ATOM 6285 C CA . ARG D 1 76 ? 12.581 -25.285 78.443 1.00 117.63 ? 76 ARG D CA 1 +ATOM 6286 C C . ARG D 1 76 ? 13.423 -24.392 79.327 1.00 112.41 ? 76 ARG D C 1 +ATOM 6287 O O . ARG D 1 76 ? 12.977 -23.895 80.354 1.00 95.99 ? 76 ARG D O 1 +ATOM 6288 C CB . ARG D 1 76 ? 11.371 -25.801 79.203 1.00 148.72 ? 76 ARG D CB 1 +ATOM 6289 C CG . ARG D 1 76 ? 10.384 -26.598 78.361 1.00 173.84 ? 76 ARG D CG 1 +ATOM 6290 C CD . ARG D 1 76 ? 9.193 -27.033 79.213 1.00 205.06 ? 76 ARG D CD 1 +ATOM 6291 N NE . ARG D 1 76 ? 9.575 -28.049 80.205 1.00 198.15 ? 76 ARG D NE 1 +ATOM 6292 C CZ . ARG D 1 76 ? 9.928 -27.802 81.468 1.00 179.06 ? 76 ARG D CZ 1 +ATOM 6293 N NH1 . ARG D 1 76 ? 9.953 -26.558 81.947 1.00 204.49 ? 76 ARG D NH1 1 +ATOM 6294 N NH2 . ARG D 1 76 ? 10.267 -28.805 82.253 1.00 150.89 ? 76 ARG D NH2 1 +ATOM 6295 N N . TRP D 1 77 ? 14.682 -24.261 78.942 1.00 127.08 ? 77 TRP D N 1 +ATOM 6296 C CA . TRP D 1 77 ? 15.594 -23.315 79.563 1.00 121.25 ? 77 TRP D CA 1 +ATOM 6297 C C . TRP D 1 77 ? 15.972 -22.214 78.568 1.00 136.11 ? 77 TRP D C 1 +ATOM 6298 O O . TRP D 1 77 ? 16.211 -21.065 78.946 1.00 106.31 ? 77 TRP D O 1 +ATOM 6299 C CB . TRP D 1 77 ? 16.859 -24.051 80.031 1.00 120.99 ? 77 TRP D CB 1 +ATOM 6300 C CG . TRP D 1 77 ? 16.807 -24.517 81.443 1.00 122.11 ? 77 TRP D CG 1 +ATOM 6301 C CD1 . TRP D 1 77 ? 16.135 -25.593 81.918 1.00 126.84 ? 77 TRP D CD1 1 +ATOM 6302 C CD2 . TRP D 1 77 ? 17.482 -23.938 82.563 1.00 116.87 ? 77 TRP D CD2 1 +ATOM 6303 N NE1 . TRP D 1 77 ? 16.330 -25.711 83.265 1.00 120.15 ? 77 TRP D NE1 1 +ATOM 6304 C CE2 . TRP D 1 77 ? 17.150 -24.698 83.684 1.00 116.32 ? 77 TRP D CE2 1 +ATOM 6305 C CE3 . TRP D 1 77 ? 18.325 -22.840 82.723 1.00 129.56 ? 77 TRP D CE3 1 +ATOM 6306 C CZ2 . TRP D 1 77 ? 17.618 -24.393 84.953 1.00 137.46 ? 77 TRP D CZ2 1 +ATOM 6307 C CZ3 . TRP D 1 77 ? 18.799 -22.546 83.983 1.00 132.74 ? 77 TRP D CZ3 1 +ATOM 6308 C CH2 . TRP D 1 77 ? 18.447 -23.321 85.082 1.00 131.47 ? 77 TRP D CH2 1 +ATOM 6309 N N . PHE D 1 78 ? 16.069 -22.595 77.292 1.00 160.95 ? 78 PHE D N 1 +ATOM 6310 C CA . PHE D 1 78 ? 16.571 -21.721 76.226 1.00 128.92 ? 78 PHE D CA 1 +ATOM 6311 C C . PHE D 1 78 ? 15.520 -21.472 75.123 1.00 115.92 ? 78 PHE D C 1 +ATOM 6312 O O . PHE D 1 78 ? 14.795 -22.393 74.730 1.00 142.18 ? 78 PHE D O 1 +ATOM 6313 C CB . PHE D 1 78 ? 17.794 -22.362 75.571 1.00 104.13 ? 78 PHE D CB 1 +ATOM 6314 C CG . PHE D 1 78 ? 18.880 -22.708 76.524 1.00 82.80 ? 78 PHE D CG 1 +ATOM 6315 C CD1 . PHE D 1 78 ? 19.684 -21.725 77.078 1.00 84.81 ? 78 PHE D CD1 1 +ATOM 6316 C CD2 . PHE D 1 78 ? 19.099 -24.016 76.862 1.00 91.70 ? 78 PHE D CD2 1 +ATOM 6317 C CE1 . PHE D 1 78 ? 20.695 -22.045 77.962 1.00 93.19 ? 78 PHE D CE1 1 +ATOM 6318 C CE2 . PHE D 1 78 ? 20.120 -24.352 77.731 1.00 117.57 ? 78 PHE D CE2 1 +ATOM 6319 C CZ . PHE D 1 78 ? 20.928 -23.364 78.274 1.00 104.44 ? 78 PHE D CZ 1 +ATOM 6320 N N . ILE D 1 79 ? 15.490 -20.245 74.607 1.00 78.76 ? 79 ILE D N 1 +ATOM 6321 C CA . ILE D 1 79 ? 14.879 -19.939 73.339 1.00 77.71 ? 79 ILE D CA 1 +ATOM 6322 C C . ILE D 1 79 ? 15.991 -19.952 72.299 1.00 95.19 ? 79 ILE D C 1 +ATOM 6323 O O . ILE D 1 79 ? 17.000 -19.247 72.442 1.00 119.73 ? 79 ILE D O 1 +ATOM 6324 C CB . ILE D 1 79 ? 14.275 -18.541 73.364 1.00 98.43 ? 79 ILE D CB 1 +ATOM 6325 C CG1 . ILE D 1 79 ? 13.418 -18.344 74.612 1.00 114.55 ? 79 ILE D CG1 1 +ATOM 6326 C CG2 . ILE D 1 79 ? 13.439 -18.290 72.110 1.00 118.01 ? 79 ILE D CG2 1 +ATOM 6327 C CD1 . ILE D 1 79 ? 13.238 -16.890 75.008 1.00 136.53 ? 79 ILE D CD1 1 +ATOM 6328 N N . PRO D 1 80 ? 15.840 -20.775 71.255 1.00 111.64 ? 80 PRO D N 1 +ATOM 6329 C CA . PRO D 1 80 ? 16.880 -20.734 70.242 1.00 119.81 ? 80 PRO D CA 1 +ATOM 6330 C C . PRO D 1 80 ? 16.556 -19.726 69.156 1.00 133.40 ? 80 PRO D C 1 +ATOM 6331 O O . PRO D 1 80 ? 15.418 -19.649 68.705 1.00 94.18 ? 80 PRO D O 1 +ATOM 6332 C CB . PRO D 1 80 ? 16.879 -22.149 69.675 1.00 107.15 ? 80 PRO D CB 1 +ATOM 6333 C CG . PRO D 1 80 ? 16.274 -22.969 70.740 1.00 125.10 ? 80 PRO D CG 1 +ATOM 6334 C CD . PRO D 1 80 ? 15.186 -22.084 71.277 1.00 124.88 ? 80 PRO D CD 1 +ATOM 6335 N N . LEU D 1 81 ? 17.545 -18.916 68.807 1.00 136.40 ? 81 LEU D N 1 +ATOM 6336 C CA . LEU D 1 81 ? 17.416 -17.988 67.721 1.00 110.76 ? 81 LEU D CA 1 +ATOM 6337 C C . LEU D 1 81 ? 17.994 -18.629 66.474 1.00 103.19 ? 81 LEU D C 1 +ATOM 6338 O O . LEU D 1 81 ? 18.986 -19.384 66.548 1.00 97.38 ? 81 LEU D O 1 +ATOM 6339 C CB . LEU D 1 81 ? 18.140 -16.708 68.067 1.00 116.14 ? 81 LEU D CB 1 +ATOM 6340 C CG . LEU D 1 81 ? 17.641 -16.127 69.382 1.00 130.42 ? 81 LEU D CG 1 +ATOM 6341 C CD1 . LEU D 1 81 ? 18.479 -14.920 69.721 1.00 119.14 ? 81 LEU D CD1 1 +ATOM 6342 C CD2 . LEU D 1 81 ? 16.173 -15.746 69.272 1.00 137.31 ? 81 LEU D CD2 1 +ATOM 6343 N N . GLU D 1 82 ? 17.305 -18.396 65.360 1.00 75.93 ? 82 GLU D N 1 +ATOM 6344 C CA . GLU D 1 82 ? 17.630 -19.053 64.095 1.00 68.61 ? 82 GLU D CA 1 +ATOM 6345 C C . GLU D 1 82 ? 18.821 -18.361 63.443 1.00 63.64 ? 82 GLU D C 1 +ATOM 6346 O O . GLU D 1 82 ? 18.716 -17.228 62.951 1.00 63.34 ? 82 GLU D O 1 +ATOM 6347 C CB . GLU D 1 82 ? 16.413 -19.074 63.128 1.00 73.42 ? 82 GLU D CB 1 +ATOM 6348 C CG . GLU D 1 82 ? 16.677 -19.700 61.751 1.00 71.15 ? 82 GLU D CG 1 +ATOM 6349 C CD . GLU D 1 82 ? 16.921 -21.221 61.773 1.00 91.26 ? 82 GLU D CD 1 +ATOM 6350 O OE1 . GLU D 1 82 ? 17.718 -21.761 62.627 1.00 84.62 ? 82 GLU D OE1 1 +ATOM 6351 O OE2 . GLU D 1 82 ? 16.302 -21.909 60.917 1.00 84.43 ? 82 GLU D OE2 1 +ATOM 6352 N N . ARG D 1 83 ? 19.926 -19.084 63.394 1.00 63.03 ? 83 ARG D N 1 +ATOM 6353 C CA . ARG D 1 83 ? 21.125 -18.636 62.701 1.00 61.41 ? 83 ARG D CA 1 +ATOM 6354 C C . ARG D 1 83 ? 21.611 -19.673 61.672 1.00 86.64 ? 83 ARG D C 1 +ATOM 6355 O O . ARG D 1 83 ? 22.357 -19.331 60.770 1.00 100.37 ? 83 ARG D O 1 +ATOM 6356 C CB . ARG D 1 83 ? 22.239 -18.338 63.706 1.00 63.68 ? 83 ARG D CB 1 +ATOM 6357 C CG . ARG D 1 83 ? 21.860 -17.320 64.767 1.00 67.35 ? 83 ARG D CG 1 +ATOM 6358 C CD . ARG D 1 83 ? 21.703 -15.928 64.207 1.00 70.05 ? 83 ARG D CD 1 +ATOM 6359 N NE . ARG D 1 83 ? 21.587 -14.955 65.300 1.00 83.17 ? 83 ARG D NE 1 +ATOM 6360 C CZ . ARG D 1 83 ? 20.455 -14.379 65.722 1.00 83.21 ? 83 ARG D CZ 1 +ATOM 6361 N NH1 . ARG D 1 83 ? 19.290 -14.636 65.114 1.00 79.77 ? 83 ARG D NH1 1 +ATOM 6362 N NH2 . ARG D 1 83 ? 20.494 -13.552 66.765 1.00 69.74 ? 83 ARG D NH2 1 +ATOM 6363 N N . GLN D 1 84 ? 21.196 -20.939 61.774 1.00 117.59 ? 84 GLN D N 1 +ATOM 6364 C CA . GLN D 1 84 ? 21.622 -21.932 60.766 1.00 109.63 ? 84 GLN D CA 1 +ATOM 6365 C C . GLN D 1 84 ? 21.172 -21.491 59.367 1.00 111.92 ? 84 GLN D C 1 +ATOM 6366 O O . GLN D 1 84 ? 21.926 -21.556 58.425 1.00 170.27 ? 84 GLN D O 1 +ATOM 6367 C CB . GLN D 1 84 ? 21.118 -23.354 61.078 1.00 110.61 ? 84 GLN D CB 1 +ATOM 6368 C CG . GLN D 1 84 ? 22.046 -24.469 60.597 1.00 103.10 ? 84 GLN D CG 1 +ATOM 6369 C CD . GLN D 1 84 ? 21.496 -25.873 60.850 1.00 119.10 ? 84 GLN D CD 1 +ATOM 6370 O OE1 . GLN D 1 84 ? 20.794 -26.110 61.825 1.00 114.93 ? 84 GLN D OE1 1 +ATOM 6371 N NE2 . GLN D 1 84 ? 21.746 -26.790 59.908 1.00 134.39 ? 84 GLN D NE2 1 +ATOM 6372 N N . GLY D 1 85 ? 19.970 -20.963 59.236 1.00 101.41 ? 85 GLY D N 1 +ATOM 6373 C CA . GLY D 1 85 ? 19.545 -20.474 57.927 1.00 86.22 ? 85 GLY D CA 1 +ATOM 6374 C C . GLY D 1 85 ? 19.479 -18.953 57.813 1.00 82.53 ? 85 GLY D C 1 +ATOM 6375 O O . GLY D 1 85 ? 18.488 -18.410 57.305 1.00 112.64 ? 85 GLY D O 1 +ATOM 6376 N N . LEU D 1 86 ? 20.429 -18.249 58.418 1.00 55.08 ? 86 LEU D N 1 +ATOM 6377 C CA . LEU D 1 86 ? 20.234 -16.826 58.716 1.00 64.51 ? 86 LEU D CA 1 +ATOM 6378 C C . LEU D 1 86 ? 19.976 -16.116 57.419 1.00 51.93 ? 86 LEU D C 1 +ATOM 6379 O O . LEU D 1 86 ? 19.331 -15.046 57.393 1.00 62.58 ? 86 LEU D O 1 +ATOM 6380 C CB . LEU D 1 86 ? 21.464 -16.247 59.469 1.00 101.69 ? 86 LEU D CB 1 +ATOM 6381 C CG . LEU D 1 86 ? 21.642 -14.722 59.679 1.00 108.57 ? 86 LEU D CG 1 +ATOM 6382 C CD1 . LEU D 1 86 ? 20.482 -14.092 60.441 1.00 94.41 ? 86 LEU D CD1 1 +ATOM 6383 C CD2 . LEU D 1 86 ? 22.977 -14.433 60.392 1.00 83.99 ? 86 LEU D CD2 1 +ATOM 6384 N N . GLN D 1 87 ? 20.587 -16.634 56.360 1.00 46.13 ? 87 GLN D N 1 +ATOM 6385 C CA . GLN D 1 87 ? 20.656 -15.869 55.124 1.00 76.82 ? 87 GLN D CA 1 +ATOM 6386 C C . GLN D 1 87 ? 19.221 -15.717 54.592 1.00 92.54 ? 87 GLN D C 1 +ATOM 6387 O O . GLN D 1 87 ? 18.826 -14.626 54.099 1.00 88.59 ? 87 GLN D O 1 +ATOM 6388 C CB . GLN D 1 87 ? 21.606 -16.561 54.126 1.00 82.53 ? 87 GLN D CB 1 +ATOM 6389 C CG . GLN D 1 87 ? 22.308 -15.587 53.173 1.00 104.57 ? 87 GLN D CG 1 +ATOM 6390 C CD . GLN D 1 87 ? 22.822 -14.300 53.851 1.00 112.36 ? 87 GLN D CD 1 +ATOM 6391 O OE1 . GLN D 1 87 ? 23.632 -14.350 54.775 1.00 80.96 ? 87 GLN D OE1 1 +ATOM 6392 N NE2 . GLN D 1 87 ? 22.380 -13.142 53.355 1.00 112.63 ? 87 GLN D NE2 1 +ATOM 6393 N N . ASN D 1 88 ? 18.434 -16.791 54.743 1.00 75.77 ? 88 ASN D N 1 +ATOM 6394 C CA . ASN D 1 88 ? 17.057 -16.822 54.232 1.00 57.07 ? 88 ASN D CA 1 +ATOM 6395 C C . ASN D 1 88 ? 16.190 -15.899 55.039 1.00 54.80 ? 88 ASN D C 1 +ATOM 6396 O O . ASN D 1 88 ? 15.277 -15.234 54.507 1.00 58.04 ? 88 ASN D O 1 +ATOM 6397 C CB . ASN D 1 88 ? 16.470 -18.212 54.325 1.00 45.72 ? 88 ASN D CB 1 +ATOM 6398 C CG . ASN D 1 88 ? 17.210 -19.230 53.491 1.00 51.29 ? 88 ASN D CG 1 +ATOM 6399 O OD1 . ASN D 1 88 ? 17.777 -18.901 52.456 1.00 57.60 ? 88 ASN D OD1 1 +ATOM 6400 N ND2 . ASN D 1 88 ? 17.340 -20.436 54.020 1.00 66.20 ? 88 ASN D ND2 1 +ATOM 6401 N N . LEU D 1 89 ? 16.511 -15.828 56.320 1.00 46.98 ? 89 LEU D N 1 +ATOM 6402 C CA . LEU D 1 89 ? 15.778 -14.973 57.229 1.00 58.19 ? 89 LEU D CA 1 +ATOM 6403 C C . LEU D 1 89 ? 15.933 -13.512 56.786 1.00 64.81 ? 89 LEU D C 1 +ATOM 6404 O O . LEU D 1 89 ? 14.973 -12.737 56.724 1.00 65.14 ? 89 LEU D O 1 +ATOM 6405 C CB . LEU D 1 89 ? 16.315 -15.218 58.648 1.00 56.97 ? 89 LEU D CB 1 +ATOM 6406 C CG . LEU D 1 89 ? 15.374 -15.063 59.820 1.00 70.15 ? 89 LEU D CG 1 +ATOM 6407 C CD1 . LEU D 1 89 ? 15.808 -13.929 60.696 1.00 69.39 ? 89 LEU D CD1 1 +ATOM 6408 C CD2 . LEU D 1 89 ? 13.928 -14.832 59.360 1.00 104.00 ? 89 LEU D CD2 1 +ATOM 6409 N N . LEU D 1 90 ? 17.163 -13.147 56.444 1.00 86.10 ? 90 LEU D N 1 +ATOM 6410 C CA . LEU D 1 90 ? 17.486 -11.755 56.083 1.00 78.97 ? 90 LEU D CA 1 +ATOM 6411 C C . LEU D 1 90 ? 16.913 -11.418 54.734 1.00 78.86 ? 90 LEU D C 1 +ATOM 6412 O O . LEU D 1 90 ? 16.514 -10.276 54.475 1.00 86.40 ? 90 LEU D O 1 +ATOM 6413 C CB . LEU D 1 90 ? 18.992 -11.558 56.050 1.00 101.80 ? 90 LEU D CB 1 +ATOM 6414 C CG . LEU D 1 90 ? 19.710 -11.804 57.385 1.00 110.47 ? 90 LEU D CG 1 +ATOM 6415 C CD1 . LEU D 1 90 ? 21.192 -12.043 57.130 1.00 84.64 ? 90 LEU D CD1 1 +ATOM 6416 C CD2 . LEU D 1 90 ? 19.459 -10.615 58.307 1.00 117.27 ? 90 LEU D CD2 1 +ATOM 6417 N N . ASN D 1 91 ? 16.812 -12.441 53.886 1.00 92.57 ? 91 ASN D N 1 +ATOM 6418 C CA . ASN D 1 91 ? 16.207 -12.289 52.574 1.00 101.51 ? 91 ASN D CA 1 +ATOM 6419 C C . ASN D 1 91 ? 14.694 -12.004 52.677 1.00 93.06 ? 91 ASN D C 1 +ATOM 6420 O O . ASN D 1 91 ? 14.182 -11.066 52.052 1.00 54.23 ? 91 ASN D O 1 +ATOM 6421 C CB . ASN D 1 91 ? 16.455 -13.562 51.766 1.00 97.79 ? 91 ASN D CB 1 +ATOM 6422 C CG . ASN D 1 91 ? 17.347 -13.373 50.579 1.00 113.76 ? 91 ASN D CG 1 +ATOM 6423 O OD1 . ASN D 1 91 ? 18.063 -12.377 50.437 1.00 103.91 ? 91 ASN D OD1 1 +ATOM 6424 N ND2 . ASN D 1 91 ? 17.255 -14.332 49.661 1.00 142.62 ? 91 ASN D ND2 1 +ATOM 6425 N N . GLU D 1 92 ? 13.985 -12.803 53.473 1.00 88.92 ? 92 GLU D N 1 +ATOM 6426 C CA . GLU D 1 92 ? 12.553 -12.572 53.658 1.00 96.06 ? 92 GLU D CA 1 +ATOM 6427 C C . GLU D 1 92 ? 12.319 -11.163 54.182 1.00 75.25 ? 92 GLU D C 1 +ATOM 6428 O O . GLU D 1 92 ? 11.315 -10.527 53.891 1.00 62.95 ? 92 GLU D O 1 +ATOM 6429 C CB . GLU D 1 92 ? 11.935 -13.638 54.593 1.00 107.51 ? 92 GLU D CB 1 +ATOM 6430 C CG . GLU D 1 92 ? 11.323 -14.839 53.876 1.00 101.31 ? 92 GLU D CG 1 +ATOM 6431 C CD . GLU D 1 92 ? 10.287 -14.464 52.798 1.00 77.03 ? 92 GLU D CD 1 +ATOM 6432 O OE1 . GLU D 1 92 ? 9.291 -13.766 53.072 1.00 42.48 ? 92 GLU D OE1 1 +ATOM 6433 O OE2 . GLU D 1 92 ? 10.503 -14.864 51.624 1.00 86.13 ? 92 GLU D OE2 1 +ATOM 6434 N N . ARG D 1 93 ? 13.211 -10.724 55.052 1.00 66.02 ? 93 ARG D N 1 +ATOM 6435 C CA . ARG D 1 93 ? 13.068 -9.420 55.652 1.00 72.39 ? 93 ARG D CA 1 +ATOM 6436 C C . ARG D 1 93 ? 13.299 -8.341 54.600 1.00 71.74 ? 93 ARG D C 1 +ATOM 6437 O O . ARG D 1 93 ? 12.687 -7.276 54.642 1.00 71.06 ? 93 ARG D O 1 +ATOM 6438 C CB . ARG D 1 93 ? 13.988 -9.312 56.883 1.00 92.89 ? 93 ARG D CB 1 +ATOM 6439 C CG . ARG D 1 93 ? 13.496 -10.190 58.051 1.00 96.78 ? 93 ARG D CG 1 +ATOM 6440 C CD . ARG D 1 93 ? 14.524 -10.406 59.152 1.00 100.58 ? 93 ARG D CD 1 +ATOM 6441 N NE . ARG D 1 93 ? 14.296 -9.564 60.312 1.00 92.16 ? 93 ARG D NE 1 +ATOM 6442 C CZ . ARG D 1 93 ? 14.905 -8.396 60.530 1.00 113.75 ? 93 ARG D CZ 1 +ATOM 6443 N NH1 . ARG D 1 93 ? 15.805 -7.884 59.680 1.00 103.38 ? 93 ARG D NH1 1 +ATOM 6444 N NH2 . ARG D 1 93 ? 14.616 -7.743 61.636 1.00 147.33 ? 93 ARG D NH2 1 +ATOM 6445 N N . LYS D 1 94 ? 14.164 -8.621 53.632 1.00 84.87 ? 94 LYS D N 1 +ATOM 6446 C CA . LYS D 1 94 ? 14.382 -7.677 52.534 1.00 94.35 ? 94 LYS D CA 1 +ATOM 6447 C C . LYS D 1 94 ? 13.097 -7.570 51.740 1.00 98.09 ? 94 LYS D C 1 +ATOM 6448 O O . LYS D 1 94 ? 12.727 -6.464 51.305 1.00 108.43 ? 94 LYS D O 1 +ATOM 6449 C CB . LYS D 1 94 ? 15.514 -8.146 51.609 1.00 95.08 ? 94 LYS D CB 1 +ATOM 6450 C CG . LYS D 1 94 ? 16.918 -7.679 51.977 1.00 95.29 ? 94 LYS D CG 1 +ATOM 6451 C CD . LYS D 1 94 ? 17.944 -8.385 51.109 1.00 110.05 ? 94 LYS D CD 1 +ATOM 6452 C CE . LYS D 1 94 ? 19.281 -7.664 51.063 1.00 118.19 ? 94 LYS D CE 1 +ATOM 6453 N NZ . LYS D 1 94 ? 20.331 -8.565 50.495 1.00 128.35 ? 94 LYS D NZ 1 +ATOM 6454 N N . ILE D 1 95 ? 12.437 -8.717 51.526 1.00 72.15 ? 95 ILE D N 1 +ATOM 6455 C CA . ILE D 1 95 ? 11.275 -8.735 50.644 1.00 56.63 ? 95 ILE D CA 1 +ATOM 6456 C C . ILE D 1 95 ? 10.153 -8.007 51.330 1.00 67.66 ? 95 ILE D C 1 +ATOM 6457 O O . ILE D 1 95 ? 9.334 -7.328 50.671 1.00 48.21 ? 95 ILE D O 1 +ATOM 6458 C CB . ILE D 1 95 ? 10.815 -10.132 50.292 1.00 55.86 ? 95 ILE D CB 1 +ATOM 6459 C CG1 . ILE D 1 95 ? 11.978 -10.989 49.806 1.00 89.25 ? 95 ILE D CG1 1 +ATOM 6460 C CG2 . ILE D 1 95 ? 9.812 -10.020 49.176 1.00 47.80 ? 95 ILE D CG2 1 +ATOM 6461 C CD1 . ILE D 1 95 ? 11.591 -12.296 49.124 1.00 108.87 ? 95 ILE D CD1 1 +ATOM 6462 N N . ILE D 1 96 ? 10.072 -8.215 52.663 1.00 89.45 ? 96 ILE D N 1 +ATOM 6463 C CA . ILE D 1 96 ? 9.078 -7.536 53.524 1.00 75.19 ? 96 ILE D CA 1 +ATOM 6464 C C . ILE D 1 96 ? 9.245 -6.053 53.410 1.00 66.12 ? 96 ILE D C 1 +ATOM 6465 O O . ILE D 1 96 ? 8.327 -5.364 52.959 1.00 63.56 ? 96 ILE D O 1 +ATOM 6466 C CB . ILE D 1 96 ? 9.198 -7.916 55.011 1.00 55.97 ? 96 ILE D CB 1 +ATOM 6467 C CG1 . ILE D 1 96 ? 8.767 -9.378 55.216 1.00 77.40 ? 96 ILE D CG1 1 +ATOM 6468 C CG2 . ILE D 1 96 ? 8.276 -7.050 55.824 1.00 50.52 ? 96 ILE D CG2 1 +ATOM 6469 C CD1 . ILE D 1 96 ? 8.791 -9.819 56.660 1.00 80.15 ? 96 ILE D CD1 1 +ATOM 6470 N N . ARG D 1 97 ? 10.437 -5.586 53.747 1.00 62.32 ? 97 ARG D N 1 +ATOM 6471 C CA . ARG D 1 97 ? 10.717 -4.159 53.696 1.00 81.71 ? 97 ARG D CA 1 +ATOM 6472 C C . ARG D 1 97 ? 10.486 -3.546 52.303 1.00 101.46 ? 97 ARG D C 1 +ATOM 6473 O O . ARG D 1 97 ? 10.086 -2.379 52.177 1.00 101.06 ? 97 ARG D O 1 +ATOM 6474 C CB . ARG D 1 97 ? 12.148 -3.869 54.138 1.00 94.05 ? 97 ARG D CB 1 +ATOM 6475 C CG . ARG D 1 97 ? 12.273 -3.357 55.563 1.00 102.20 ? 97 ARG D CG 1 +ATOM 6476 C CD . ARG D 1 97 ? 13.721 -3.031 55.913 1.00 98.45 ? 97 ARG D CD 1 +ATOM 6477 N NE . ARG D 1 97 ? 14.486 -4.225 56.276 1.00 86.38 ? 97 ARG D NE 1 +ATOM 6478 C CZ . ARG D 1 97 ? 14.725 -4.615 57.521 1.00 91.21 ? 97 ARG D CZ 1 +ATOM 6479 N NH1 . ARG D 1 97 ? 14.244 -3.923 58.566 1.00 74.09 ? 97 ARG D NH1 1 +ATOM 6480 N NH2 . ARG D 1 97 ? 15.440 -5.718 57.727 1.00 109.47 ? 97 ARG D NH2 1 +ATOM 6481 N N . ALA D 1 98 ? 10.722 -4.329 51.255 1.00 108.38 ? 98 ALA D N 1 +ATOM 6482 C CA . ALA D 1 98 ? 10.488 -3.855 49.900 1.00 101.42 ? 98 ALA D CA 1 +ATOM 6483 C C . ALA D 1 98 ? 8.987 -3.822 49.583 1.00 107.16 ? 98 ALA D C 1 +ATOM 6484 O O . ALA D 1 98 ? 8.544 -3.008 48.765 1.00 100.94 ? 98 ALA D O 1 +ATOM 6485 C CB . ALA D 1 98 ? 11.227 -4.744 48.918 1.00 114.82 ? 98 ALA D CB 1 +ATOM 6486 N N . ALA D 1 99 ? 8.223 -4.704 50.241 1.00 96.81 ? 99 ALA D N 1 +ATOM 6487 C CA . ALA D 1 99 ? 6.766 -4.800 50.051 1.00 86.64 ? 99 ALA D CA 1 +ATOM 6488 C C . ALA D 1 99 ? 6.021 -3.619 50.616 1.00 93.41 ? 99 ALA D C 1 +ATOM 6489 O O . ALA D 1 99 ? 5.245 -2.946 49.918 1.00 158.36 ? 99 ALA D O 1 +ATOM 6490 C CB . ALA D 1 99 ? 6.234 -6.037 50.719 1.00 88.60 ? 99 ALA D CB 1 +ATOM 6491 N N . GLN D 1 100 ? 6.321 -3.297 51.866 1.00 88.92 ? 100 GLN D N 1 +ATOM 6492 C CA . GLN D 1 100 ? 5.517 -2.321 52.608 1.00 95.33 ? 100 GLN D CA 1 +ATOM 6493 C C . GLN D 1 100 ? 6.121 -0.906 52.785 1.00 94.77 ? 100 GLN D C 1 +ATOM 6494 O O . GLN D 1 100 ? 5.557 -0.065 53.488 1.00 92.61 ? 100 GLN D O 1 +ATOM 6495 C CB . GLN D 1 100 ? 5.157 -2.900 53.970 1.00 86.32 ? 100 GLN D CB 1 +ATOM 6496 C CG . GLN D 1 100 ? 6.301 -3.571 54.697 1.00 79.39 ? 100 GLN D CG 1 +ATOM 6497 C CD . GLN D 1 100 ? 5.831 -4.651 55.648 1.00 68.31 ? 100 GLN D CD 1 +ATOM 6498 O OE1 . GLN D 1 100 ? 5.220 -5.664 55.243 1.00 52.54 ? 100 GLN D OE1 1 +ATOM 6499 N NE2 . GLN D 1 100 ? 6.174 -4.473 56.925 1.00 61.91 ? 100 GLN D NE2 1 +ATOM 6500 N N . GLU D 1 101 ? 7.237 -0.637 52.121 1.00 102.15 ? 101 GLU D N 1 +ATOM 6501 C CA . GLU D 1 101 ? 7.896 0.658 52.244 1.00 116.79 ? 101 GLU D CA 1 +ATOM 6502 C C . GLU D 1 101 ? 7.066 1.803 51.654 1.00 124.34 ? 101 GLU D C 1 +ATOM 6503 O O . GLU D 1 101 ? 7.262 2.967 52.023 1.00 135.17 ? 101 GLU D O 1 +ATOM 6504 C CB . GLU D 1 101 ? 9.296 0.617 51.607 1.00 141.47 ? 101 GLU D CB 1 +ATOM 6505 C CG . GLU D 1 101 ? 9.338 0.095 50.170 1.00 148.48 ? 101 GLU D CG 1 +ATOM 6506 C CD . GLU D 1 101 ? 10.735 0.132 49.572 1.00 141.21 ? 101 GLU D CD 1 +ATOM 6507 O OE1 . GLU D 1 101 ? 11.709 0.278 50.348 1.00 134.19 ? 101 GLU D OE1 1 +ATOM 6508 O OE2 . GLU D 1 101 ? 10.858 0.086 48.324 1.00 131.82 ? 101 GLU D OE2 1 +ATOM 6509 N N . ASN D 1 102 ? 6.179 1.492 50.711 1.00 114.79 ? 102 ASN D N 1 +ATOM 6510 C CA . ASN D 1 102 ? 5.413 2.528 50.036 1.00 119.74 ? 102 ASN D CA 1 +ATOM 6511 C C . ASN D 1 102 ? 4.076 2.797 50.701 1.00 134.76 ? 102 ASN D C 1 +ATOM 6512 O O . ASN D 1 102 ? 3.336 3.686 50.272 1.00 174.30 ? 102 ASN D O 1 +ATOM 6513 C CB . ASN D 1 102 ? 5.182 2.155 48.581 1.00 119.52 ? 102 ASN D CB 1 +ATOM 6514 C CG . ASN D 1 102 ? 6.436 2.265 47.756 1.00 146.33 ? 102 ASN D CG 1 +ATOM 6515 O OD1 . ASN D 1 102 ? 6.854 3.369 47.363 1.00 192.64 ? 102 ASN D OD1 1 +ATOM 6516 N ND2 . ASN D 1 102 ? 7.086 1.129 47.533 1.00 166.33 ? 102 ASN D ND2 1 +ATOM 6517 N N . GLY D 1 103 ? 3.759 2.047 51.751 1.00 123.61 ? 103 GLY D N 1 +ATOM 6518 C CA . GLY D 1 103 ? 2.489 2.237 52.452 1.00 118.75 ? 103 GLY D CA 1 +ATOM 6519 C C . GLY D 1 103 ? 1.270 2.041 51.569 1.00 104.79 ? 103 GLY D C 1 +ATOM 6520 O O . GLY D 1 103 ? 0.237 2.692 51.747 1.00 104.77 ? 103 GLY D O 1 +ATOM 6521 N N . THR D 1 104 ? 1.382 1.133 50.610 1.00 103.95 ? 104 THR D N 1 +ATOM 6522 C CA . THR D 1 104 ? 0.217 0.674 49.882 1.00 108.84 ? 104 THR D CA 1 +ATOM 6523 C C . THR D 1 104 ? -0.259 -0.665 50.458 1.00 102.62 ? 104 THR D C 1 +ATOM 6524 O O . THR D 1 104 ? -1.439 -0.978 50.375 1.00 87.12 ? 104 THR D O 1 +ATOM 6525 C CB . THR D 1 104 ? 0.487 0.553 48.361 1.00 111.62 ? 104 THR D CB 1 +ATOM 6526 O OG1 . THR D 1 104 ? 1.465 -0.471 48.111 1.00 97.50 ? 104 THR D OG1 1 +ATOM 6527 C CG2 . THR D 1 104 ? 0.953 1.889 47.794 1.00 91.18 ? 104 THR D CG2 1 +ATOM 6528 N N . VAL D 1 105 ? 0.640 -1.434 51.070 1.00 103.67 ? 105 VAL D N 1 +ATOM 6529 C CA . VAL D 1 105 ? 0.307 -2.816 51.456 1.00 122.33 ? 105 VAL D CA 1 +ATOM 6530 C C . VAL D 1 105 ? -0.841 -2.821 52.453 1.00 115.86 ? 105 VAL D C 1 +ATOM 6531 O O . VAL D 1 105 ? -0.916 -1.957 53.333 1.00 101.60 ? 105 VAL D O 1 +ATOM 6532 C CB . VAL D 1 105 ? 1.535 -3.627 51.987 1.00 138.85 ? 105 VAL D CB 1 +ATOM 6533 C CG1 . VAL D 1 105 ? 1.138 -4.609 53.085 1.00 120.42 ? 105 VAL D CG1 1 +ATOM 6534 C CG2 . VAL D 1 105 ? 2.229 -4.384 50.840 1.00 140.16 ? 105 VAL D CG2 1 +ATOM 6535 N N . ALA D 1 106 ? -1.738 -3.790 52.265 1.00 127.12 ? 106 ALA D N 1 +ATOM 6536 C CA . ALA D 1 106 ? -2.985 -3.875 52.999 1.00 135.26 ? 106 ALA D CA 1 +ATOM 6537 C C . ALA D 1 106 ? -2.726 -4.040 54.495 1.00 163.32 ? 106 ALA D C 1 +ATOM 6538 O O . ALA D 1 106 ? -1.897 -4.855 54.914 1.00 199.80 ? 106 ALA D O 1 +ATOM 6539 C CB . ALA D 1 106 ? -3.816 -5.037 52.475 1.00 124.34 ? 106 ALA D CB 1 +ATOM 6540 N N . ILE D 1 107 ? -3.452 -3.267 55.299 1.00 161.40 ? 107 ILE D N 1 +ATOM 6541 C CA . ILE D 1 107 ? -3.220 -3.202 56.746 1.00 155.52 ? 107 ILE D CA 1 +ATOM 6542 C C . ILE D 1 107 ? -3.357 -4.578 57.444 1.00 149.57 ? 107 ILE D C 1 +ATOM 6543 O O . ILE D 1 107 ? -2.691 -4.853 58.449 1.00 112.05 ? 107 ILE D O 1 +ATOM 6544 C CB . ILE D 1 107 ? -4.166 -2.157 57.393 1.00 147.11 ? 107 ILE D CB 1 +ATOM 6545 C CG1 . ILE D 1 107 ? -3.735 -1.843 58.832 1.00 153.99 ? 107 ILE D CG1 1 +ATOM 6546 C CG2 . ILE D 1 107 ? -5.614 -2.639 57.356 1.00 148.82 ? 107 ILE D CG2 1 +ATOM 6547 C CD1 . ILE D 1 107 ? -2.311 -1.336 58.979 1.00 134.93 ? 107 ILE D CD1 1 +ATOM 6548 N N . ASN D 1 108 ? -4.220 -5.434 56.902 1.00 164.88 ? 108 ASN D N 1 +ATOM 6549 C CA . ASN D 1 108 ? -4.383 -6.809 57.393 1.00 166.51 ? 108 ASN D CA 1 +ATOM 6550 C C . ASN D 1 108 ? -3.160 -7.654 57.064 1.00 155.66 ? 108 ASN D C 1 +ATOM 6551 O O . ASN D 1 108 ? -2.774 -8.542 57.822 1.00 160.24 ? 108 ASN D O 1 +ATOM 6552 C CB . ASN D 1 108 ? -5.617 -7.470 56.760 1.00 166.21 ? 108 ASN D CB 1 +ATOM 6553 C CG . ASN D 1 108 ? -6.718 -6.476 56.438 1.00 175.74 ? 108 ASN D CG 1 +ATOM 6554 O OD1 . ASN D 1 108 ? -7.542 -6.148 57.292 1.00 218.28 ? 108 ASN D OD1 1 +ATOM 6555 N ND2 . ASN D 1 108 ? -6.727 -5.977 55.205 1.00 148.67 ? 108 ASN D ND2 1 +ATOM 6556 N N . ASN D 1 109 ? -2.574 -7.382 55.906 1.00 142.54 ? 109 ASN D N 1 +ATOM 6557 C CA . ASN D 1 109 ? -1.470 -8.173 55.381 1.00 144.35 ? 109 ASN D CA 1 +ATOM 6558 C C . ASN D 1 109 ? -0.103 -7.724 55.910 1.00 137.12 ? 109 ASN D C 1 +ATOM 6559 O O . ASN D 1 109 ? 0.881 -8.458 55.803 1.00 108.00 ? 109 ASN D O 1 +ATOM 6560 C CB . ASN D 1 109 ? -1.486 -8.117 53.849 1.00 148.76 ? 109 ASN D CB 1 +ATOM 6561 C CG . ASN D 1 109 ? -1.732 -9.472 53.222 1.00 158.60 ? 109 ASN D CG 1 +ATOM 6562 O OD1 . ASN D 1 109 ? -0.857 -10.024 52.557 1.00 168.66 ? 109 ASN D OD1 1 +ATOM 6563 N ND2 . ASN D 1 109 ? -2.913 -10.036 53.466 1.00 163.32 ? 109 ASN D ND2 1 +ATOM 6564 N N . ARG D 1 110 ? -0.060 -6.513 56.471 1.00 132.28 ? 110 ARG D N 1 +ATOM 6565 C CA . ARG D 1 110 ? 1.196 -5.842 56.881 1.00 98.27 ? 110 ARG D CA 1 +ATOM 6566 C C . ARG D 1 110 ? 1.978 -6.683 57.887 1.00 85.12 ? 110 ARG D C 1 +ATOM 6567 O O . ARG D 1 110 ? 1.399 -7.235 58.819 1.00 105.44 ? 110 ARG D O 1 +ATOM 6568 C CB . ARG D 1 110 ? 0.858 -4.488 57.516 1.00 90.83 ? 110 ARG D CB 1 +ATOM 6569 C CG . ARG D 1 110 ? 1.979 -3.475 57.490 1.00 104.54 ? 110 ARG D CG 1 +ATOM 6570 C CD . ARG D 1 110 ? 1.458 -2.054 57.325 1.00 116.47 ? 110 ARG D CD 1 +ATOM 6571 N NE . ARG D 1 110 ? 1.160 -1.416 58.609 1.00 140.48 ? 110 ARG D NE 1 +ATOM 6572 C CZ . ARG D 1 110 ? 1.739 -0.299 59.064 1.00 156.67 ? 110 ARG D CZ 1 +ATOM 6573 N NH1 . ARG D 1 110 ? 2.681 0.338 58.360 1.00 134.33 ? 110 ARG D NH1 1 +ATOM 6574 N NH2 . ARG D 1 110 ? 1.365 0.194 60.243 1.00 165.04 ? 110 ARG D NH2 1 +ATOM 6575 N N . ILE D 1 111 ? 3.282 -6.815 57.684 1.00 76.16 ? 111 ILE D N 1 +ATOM 6576 C CA . ILE D 1 111 ? 4.127 -7.515 58.653 1.00 75.42 ? 111 ILE D CA 1 +ATOM 6577 C C . ILE D 1 111 ? 5.029 -6.530 59.381 1.00 82.48 ? 111 ILE D C 1 +ATOM 6578 O O . ILE D 1 111 ? 5.862 -5.909 58.743 1.00 75.03 ? 111 ILE D O 1 +ATOM 6579 C CB . ILE D 1 111 ? 5.016 -8.568 57.986 1.00 69.71 ? 111 ILE D CB 1 +ATOM 6580 C CG1 . ILE D 1 111 ? 4.141 -9.661 57.369 1.00 85.26 ? 111 ILE D CG1 1 +ATOM 6581 C CG2 . ILE D 1 111 ? 5.975 -9.177 59.009 1.00 58.69 ? 111 ILE D CG2 1 +ATOM 6582 C CD1 . ILE D 1 111 ? 4.881 -10.606 56.431 1.00 107.64 ? 111 ILE D CD1 1 +ATOM 6583 N N . PRO D 1 112 ? 4.880 -6.407 60.715 1.00 102.69 ? 112 PRO D N 1 +ATOM 6584 C CA . PRO D 1 112 ? 5.662 -5.446 61.474 1.00 93.32 ? 112 PRO D CA 1 +ATOM 6585 C C . PRO D 1 112 ? 7.037 -6.017 61.761 1.00 114.15 ? 112 PRO D C 1 +ATOM 6586 O O . PRO D 1 112 ? 7.164 -7.165 62.228 1.00 75.59 ? 112 PRO D O 1 +ATOM 6587 C CB . PRO D 1 112 ? 4.864 -5.278 62.759 1.00 85.53 ? 112 PRO D CB 1 +ATOM 6588 C CG . PRO D 1 112 ? 4.212 -6.608 62.958 1.00 105.40 ? 112 PRO D CG 1 +ATOM 6589 C CD . PRO D 1 112 ? 4.019 -7.225 61.592 1.00 122.18 ? 112 PRO D CD 1 +ATOM 6590 N N . LEU D 1 113 ? 8.062 -5.233 61.431 1.00 133.28 ? 113 LEU D N 1 +ATOM 6591 C CA . LEU D 1 113 ? 9.439 -5.698 61.511 1.00 117.78 ? 113 LEU D CA 1 +ATOM 6592 C C . LEU D 1 113 ? 10.175 -5.090 62.679 1.00 104.22 ? 113 LEU D C 1 +ATOM 6593 O O . LEU D 1 113 ? 10.057 -3.895 62.988 1.00 99.05 ? 113 LEU D O 1 +ATOM 6594 C CB . LEU D 1 113 ? 10.199 -5.413 60.224 1.00 114.90 ? 113 LEU D CB 1 +ATOM 6595 C CG . LEU D 1 113 ? 10.068 -6.487 59.150 1.00 116.77 ? 113 LEU D CG 1 +ATOM 6596 C CD1 . LEU D 1 113 ? 10.954 -6.078 57.993 1.00 139.42 ? 113 LEU D CD1 1 +ATOM 6597 C CD2 . LEU D 1 113 ? 10.451 -7.876 59.648 1.00 101.54 ? 113 LEU D CD2 1 +ATOM 6598 N N . GLN D 1 114 ? 10.980 -5.936 63.298 1.00 88.06 ? 114 GLN D N 1 +ATOM 6599 C CA . GLN D 1 114 ? 11.592 -5.628 64.556 1.00 95.97 ? 114 GLN D CA 1 +ATOM 6600 C C . GLN D 1 114 ? 12.989 -6.143 64.410 1.00 99.63 ? 114 GLN D C 1 +ATOM 6601 O O . GLN D 1 114 ? 13.205 -7.148 63.715 1.00 149.07 ? 114 GLN D O 1 +ATOM 6602 C CB . GLN D 1 114 ? 10.845 -6.356 65.672 1.00 89.83 ? 114 GLN D CB 1 +ATOM 6603 C CG . GLN D 1 114 ? 10.901 -5.661 67.009 1.00 89.96 ? 114 GLN D CG 1 +ATOM 6604 C CD . GLN D 1 114 ? 10.789 -6.667 68.119 1.00 105.06 ? 114 GLN D CD 1 +ATOM 6605 O OE1 . GLN D 1 114 ? 10.155 -7.716 67.952 1.00 118.11 ? 114 GLN D OE1 1 +ATOM 6606 N NE2 . GLN D 1 114 ? 11.409 -6.369 69.264 1.00 124.92 ? 114 GLN D NE2 1 +ATOM 6607 N N . SER D 1 115 ? 13.937 -5.460 65.037 1.00 81.83 ? 115 SER D N 1 +ATOM 6608 C CA . SER D 1 115 ? 15.319 -5.875 64.965 1.00 87.97 ? 115 SER D CA 1 +ATOM 6609 C C . SER D 1 115 ? 15.489 -7.352 65.382 1.00 81.81 ? 115 SER D C 1 +ATOM 6610 O O . SER D 1 115 ? 14.681 -7.901 66.137 1.00 51.92 ? 115 SER D O 1 +ATOM 6611 C CB . SER D 1 115 ? 16.195 -4.978 65.845 1.00 90.10 ? 115 SER D CB 1 +ATOM 6612 O OG . SER D 1 115 ? 15.725 -4.949 67.182 1.00 88.46 ? 115 SER D OG 1 +ATOM 6613 N N . LEU D 1 116 ? 16.520 -8.010 64.854 1.00 84.67 ? 116 LEU D N 1 +ATOM 6614 C CA . LEU D 1 116 ? 16.583 -9.434 65.038 1.00 88.46 ? 116 LEU D CA 1 +ATOM 6615 C C . LEU D 1 116 ? 16.914 -9.641 66.497 1.00 99.98 ? 116 LEU D C 1 +ATOM 6616 O O . LEU D 1 116 ? 17.913 -9.093 66.977 1.00 144.26 ? 116 LEU D O 1 +ATOM 6617 C CB . LEU D 1 116 ? 17.639 -10.080 64.140 1.00 93.75 ? 116 LEU D CB 1 +ATOM 6618 C CG . LEU D 1 116 ? 17.369 -10.033 62.648 1.00 88.68 ? 116 LEU D CG 1 +ATOM 6619 C CD1 . LEU D 1 116 ? 18.054 -8.830 61.986 1.00 108.35 ? 116 LEU D CD1 1 +ATOM 6620 C CD2 . LEU D 1 116 ? 17.862 -11.339 62.033 1.00 98.11 ? 116 LEU D CD2 1 +ATOM 6621 N N . THR D 1 117 ? 16.106 -10.442 67.184 1.00 98.56 ? 117 THR D N 1 +ATOM 6622 C CA . THR D 1 117 ? 16.376 -10.791 68.571 1.00 109.65 ? 117 THR D CA 1 +ATOM 6623 C C . THR D 1 117 ? 17.783 -11.365 68.674 1.00 98.12 ? 117 THR D C 1 +ATOM 6624 O O . THR D 1 117 ? 18.146 -12.244 67.901 1.00 116.26 ? 117 THR D O 1 +ATOM 6625 C CB . THR D 1 117 ? 15.375 -11.831 69.117 1.00 96.55 ? 117 THR D CB 1 +ATOM 6626 O OG1 . THR D 1 117 ? 14.041 -11.363 68.893 1.00 138.92 ? 117 THR D OG1 1 +ATOM 6627 C CG2 . THR D 1 117 ? 15.570 -12.030 70.605 1.00 95.43 ? 117 THR D CG2 1 +ATOM 6628 N N . ALA D 1 118 ? 18.550 -10.873 69.641 1.00 77.45 ? 118 ALA D N 1 +ATOM 6629 C CA . ALA D 1 118 ? 19.952 -11.187 69.719 1.00 75.16 ? 118 ALA D CA 1 +ATOM 6630 C C . ALA D 1 118 ? 20.242 -12.012 70.950 1.00 96.91 ? 118 ALA D C 1 +ATOM 6631 O O . ALA D 1 118 ? 19.795 -11.680 72.064 1.00 123.09 ? 118 ALA D O 1 +ATOM 6632 C CB . ALA D 1 118 ? 20.776 -9.915 69.723 1.00 63.73 ? 118 ALA D CB 1 +ATOM 6633 N N . ALA D 1 119 ? 21.151 -12.961 70.770 1.00 94.62 ? 119 ALA D N 1 +ATOM 6634 C CA . ALA D 1 119 ? 21.550 -13.871 71.821 1.00 105.71 ? 119 ALA D CA 1 +ATOM 6635 C C . ALA D 1 119 ? 22.656 -13.332 72.739 1.00 97.58 ? 119 ALA D C 1 +ATOM 6636 O O . ALA D 1 119 ? 23.456 -12.483 72.325 1.00 54.34 ? 119 ALA D O 1 +ATOM 6637 C CB . ALA D 1 119 ? 22.021 -15.159 71.197 1.00 147.46 ? 119 ALA D CB 1 +ATOM 6638 N N . ASN D 1 120 ? 22.708 -13.847 73.980 1.00 97.76 ? 120 ASN D N 1 +ATOM 6639 C CA . ASN D 1 120 ? 23.787 -13.483 74.894 1.00 93.12 ? 120 ASN D CA 1 +ATOM 6640 C C . ASN D 1 120 ? 24.869 -14.516 74.962 1.00 70.02 ? 120 ASN D C 1 +ATOM 6641 O O . ASN D 1 120 ? 26.074 -14.198 74.916 1.00 80.49 ? 120 ASN D O 1 +ATOM 6642 C CB . ASN D 1 120 ? 23.301 -13.223 76.310 1.00 101.93 ? 120 ASN D CB 1 +ATOM 6643 C CG . ASN D 1 120 ? 24.435 -12.735 77.220 1.00 123.58 ? 120 ASN D CG 1 +ATOM 6644 O OD1 . ASN D 1 120 ? 24.525 -13.168 78.363 1.00 190.22 ? 120 ASN D OD1 1 +ATOM 6645 N ND2 . ASN D 1 120 ? 25.354 -11.890 76.691 1.00 102.07 ? 120 ASN D ND2 1 +ATOM 6646 N N . ILE D 1 121 ? 24.464 -15.755 75.104 1.00 63.61 ? 121 ILE D N 1 +ATOM 6647 C CA . ILE D 1 121 ? 25.430 -16.813 75.000 1.00 115.99 ? 121 ILE D CA 1 +ATOM 6648 C C . ILE D 1 121 ? 25.167 -17.530 73.681 1.00 120.32 ? 121 ILE D C 1 +ATOM 6649 O O . ILE D 1 121 ? 24.039 -17.737 73.299 1.00 89.32 ? 121 ILE D O 1 +ATOM 6650 C CB . ILE D 1 121 ? 25.389 -17.780 76.224 1.00 157.14 ? 121 ILE D CB 1 +ATOM 6651 C CG1 . ILE D 1 121 ? 24.145 -18.684 76.200 1.00 168.81 ? 121 ILE D CG1 1 +ATOM 6652 C CG2 . ILE D 1 121 ? 25.479 -16.999 77.528 1.00 140.40 ? 121 ILE D CG2 1 +ATOM 6653 C CD1 . ILE D 1 121 ? 24.457 -20.145 75.928 1.00 190.51 ? 121 ILE D CD1 1 +ATOM 6654 N N . MET D 1 122 ? 26.228 -17.968 73.018 1.00 145.32 ? 122 MET D N 1 +ATOM 6655 C CA . MET D 1 122 ? 26.058 -18.923 71.955 1.00 126.02 ? 122 MET D CA 1 +ATOM 6656 C C . MET D 1 122 ? 26.851 -20.196 72.249 1.00 108.38 ? 122 MET D C 1 +ATOM 6657 O O . MET D 1 122 ? 27.903 -20.159 72.888 1.00 71.77 ? 122 MET D O 1 +ATOM 6658 C CB . MET D 1 122 ? 26.453 -18.282 70.634 1.00 149.56 ? 122 MET D CB 1 +ATOM 6659 C CG . MET D 1 122 ? 27.880 -17.754 70.551 1.00 133.44 ? 122 MET D CG 1 +ATOM 6660 S SD . MET D 1 122 ? 28.439 -17.798 68.840 1.00 106.31 ? 122 MET D SD 1 +ATOM 6661 C CE . MET D 1 122 ? 30.103 -18.386 69.033 1.00 107.36 ? 122 MET D CE 1 +ATOM 6662 N N . VAL D 1 123 ? 26.263 -21.331 71.898 1.00 89.24 ? 123 VAL D N 1 +ATOM 6663 C CA . VAL D 1 123 ? 26.900 -22.608 72.171 1.00 99.08 ? 123 VAL D CA 1 +ATOM 6664 C C . VAL D 1 123 ? 27.233 -23.320 70.887 1.00 87.90 ? 123 VAL D C 1 +ATOM 6665 O O . VAL D 1 123 ? 26.376 -23.494 70.014 1.00 69.75 ? 123 VAL D O 1 +ATOM 6666 C CB . VAL D 1 123 ? 26.014 -23.538 73.010 1.00 120.61 ? 123 VAL D CB 1 +ATOM 6667 C CG1 . VAL D 1 123 ? 24.564 -23.450 72.574 1.00 125.38 ? 123 VAL D CG1 1 +ATOM 6668 C CG2 . VAL D 1 123 ? 26.519 -24.986 72.945 1.00 150.49 ? 123 VAL D CG2 1 +ATOM 6669 N N . GLU D 1 124 ? 28.493 -23.731 70.758 1.00 85.50 ? 124 GLU D N 1 +ATOM 6670 C CA . GLU D 1 124 ? 28.913 -24.527 69.600 1.00 97.34 ? 124 GLU D CA 1 +ATOM 6671 C C . GLU D 1 124 ? 29.671 -25.740 70.056 1.00 72.54 ? 124 GLU D C 1 +ATOM 6672 O O . GLU D 1 124 ? 30.006 -25.855 71.196 1.00 50.29 ? 124 GLU D O 1 +ATOM 6673 C CB . GLU D 1 124 ? 29.777 -23.718 68.609 1.00 121.45 ? 124 GLU D CB 1 +ATOM 6674 C CG . GLU D 1 124 ? 30.614 -22.612 69.214 1.00 121.52 ? 124 GLU D CG 1 +ATOM 6675 C CD . GLU D 1 124 ? 31.100 -21.639 68.161 1.00 133.18 ? 124 GLU D CD 1 +ATOM 6676 O OE1 . GLU D 1 124 ? 30.344 -21.330 67.218 1.00 162.25 ? 124 GLU D OE1 1 +ATOM 6677 O OE2 . GLU D 1 124 ? 32.217 -21.137 68.296 1.00 149.77 ? 124 GLU D OE2 1 +ATOM 6678 N N . GLY D 1 125 ? 29.923 -26.643 69.121 1.00 87.33 ? 125 GLY D N 1 +ATOM 6679 C CA . GLY D 1 125 ? 30.538 -27.906 69.432 1.00 88.06 ? 125 GLY D CA 1 +ATOM 6680 C C . GLY D 1 125 ? 30.875 -28.693 68.185 1.00 89.67 ? 125 GLY D C 1 +ATOM 6681 O O . GLY D 1 125 ? 30.917 -28.158 67.076 1.00 88.86 ? 125 GLY D O 1 +ATOM 6682 N N . SER D 1 126 ? 31.071 -29.985 68.360 1.00 87.62 ? 126 SER D N 1 +ATOM 6683 C CA . SER D 1 126 ? 31.540 -30.808 67.266 1.00 83.48 ? 126 SER D CA 1 +ATOM 6684 C C . SER D 1 126 ? 31.269 -32.254 67.596 1.00 88.51 ? 126 SER D C 1 +ATOM 6685 O O . SER D 1 126 ? 31.310 -32.646 68.754 1.00 93.76 ? 126 SER D O 1 +ATOM 6686 C CB . SER D 1 126 ? 33.047 -30.631 67.039 1.00 66.54 ? 126 SER D CB 1 +ATOM 6687 O OG . SER D 1 126 ? 33.478 -29.314 67.347 1.00 59.28 ? 126 SER D OG 1 +ATOM 6688 N N . ILE D 1 127 ? 31.028 -33.059 66.570 1.00 88.87 ? 127 ILE D N 1 +ATOM 6689 C CA . ILE D 1 127 ? 31.057 -34.495 66.752 1.00 81.52 ? 127 ILE D CA 1 +ATOM 6690 C C . ILE D 1 127 ? 32.505 -34.901 66.733 1.00 102.84 ? 127 ILE D C 1 +ATOM 6691 O O . ILE D 1 127 ? 33.140 -34.963 65.681 1.00 156.59 ? 127 ILE D O 1 +ATOM 6692 C CB . ILE D 1 127 ? 30.268 -35.252 65.674 1.00 90.17 ? 127 ILE D CB 1 +ATOM 6693 C CG1 . ILE D 1 127 ? 28.749 -34.961 65.796 1.00 94.56 ? 127 ILE D CG1 1 +ATOM 6694 C CG2 . ILE D 1 127 ? 30.516 -36.748 65.800 1.00 92.42 ? 127 ILE D CG2 1 +ATOM 6695 C CD1 . ILE D 1 127 ? 27.981 -35.022 64.480 1.00 64.73 ? 127 ILE D CD1 1 +ATOM 6696 N N . ILE D 1 128 ? 33.051 -35.153 67.917 1.00 108.49 ? 128 ILE D N 1 +ATOM 6697 C CA . ILE D 1 128 ? 34.462 -35.492 68.049 1.00 99.04 ? 128 ILE D CA 1 +ATOM 6698 C C . ILE D 1 128 ? 34.669 -36.999 68.117 1.00 96.32 ? 128 ILE D C 1 +ATOM 6699 O O . ILE D 1 128 ? 34.660 -37.588 69.198 1.00 128.07 ? 128 ILE D O 1 +ATOM 6700 C CB . ILE D 1 128 ? 35.083 -34.843 69.300 1.00 93.49 ? 128 ILE D CB 1 +ATOM 6701 C CG1 . ILE D 1 128 ? 35.104 -33.320 69.157 1.00 86.75 ? 128 ILE D CG1 1 +ATOM 6702 C CG2 . ILE D 1 128 ? 36.487 -35.380 69.537 1.00 107.08 ? 128 ILE D CG2 1 +ATOM 6703 C CD1 . ILE D 1 128 ? 35.451 -32.591 70.436 1.00 96.15 ? 128 ILE D CD1 1 +ATOM 6704 N N . GLY D 1 129 ? 34.856 -37.620 66.957 1.00 85.41 ? 129 GLY D N 1 +ATOM 6705 C CA . GLY D 1 129 ? 35.081 -39.054 66.902 1.00 118.48 ? 129 GLY D CA 1 +ATOM 6706 C C . GLY D 1 129 ? 33.902 -40.034 66.754 1.00 132.50 ? 129 GLY D C 1 +ATOM 6707 O O . GLY D 1 129 ? 32.829 -39.906 67.369 1.00 139.42 ? 129 GLY D O 1 +ATOM 6708 N N . TYR D 1 130 ? 34.119 -41.004 65.876 1.00 114.86 ? 130 TYR D N 1 +ATOM 6709 C CA . TYR D 1 130 ? 33.291 -42.201 65.796 1.00 91.21 ? 130 TYR D CA 1 +ATOM 6710 C C . TYR D 1 130 ? 34.234 -43.335 65.500 1.00 85.06 ? 130 TYR D C 1 +ATOM 6711 O O . TYR D 1 130 ? 34.867 -43.374 64.440 1.00 76.42 ? 130 TYR D O 1 +ATOM 6712 C CB . TYR D 1 130 ? 32.263 -42.086 64.676 1.00 98.34 ? 130 TYR D CB 1 +ATOM 6713 C CG . TYR D 1 130 ? 31.473 -43.333 64.414 1.00 100.28 ? 130 TYR D CG 1 +ATOM 6714 C CD1 . TYR D 1 130 ? 32.074 -44.475 63.850 1.00 94.77 ? 130 TYR D CD1 1 +ATOM 6715 C CD2 . TYR D 1 130 ? 30.104 -43.348 64.633 1.00 118.95 ? 130 TYR D CD2 1 +ATOM 6716 C CE1 . TYR D 1 130 ? 31.330 -45.606 63.556 1.00 105.02 ? 130 TYR D CE1 1 +ATOM 6717 C CE2 . TYR D 1 130 ? 29.349 -44.476 64.352 1.00 138.80 ? 130 TYR D CE2 1 +ATOM 6718 C CZ . TYR D 1 130 ? 29.966 -45.604 63.827 1.00 120.83 ? 130 TYR D CZ 1 +ATOM 6719 O OH . TYR D 1 130 ? 29.186 -46.715 63.605 1.00 122.58 ? 130 TYR D OH 1 +ATOM 6720 N N . GLU D 1 131 ? 34.514 -44.133 66.509 1.00 111.42 ? 131 GLU D N 1 +ATOM 6721 C CA . GLU D 1 131 ? 35.354 -45.309 66.305 1.00 138.60 ? 131 GLU D CA 1 +ATOM 6722 C C . GLU D 1 131 ? 34.408 -46.483 66.114 1.00 142.48 ? 131 GLU D C 1 +ATOM 6723 O O . GLU D 1 131 ? 33.323 -46.492 66.685 1.00 106.75 ? 131 GLU D O 1 +ATOM 6724 C CB . GLU D 1 131 ? 36.297 -45.507 67.496 1.00 133.58 ? 131 GLU D CB 1 +ATOM 6725 C CG . GLU D 1 131 ? 37.340 -46.595 67.323 1.00 130.15 ? 131 GLU D CG 1 +ATOM 6726 C CD . GLU D 1 131 ? 38.611 -46.123 66.626 1.00 162.38 ? 131 GLU D CD 1 +ATOM 6727 O OE1 . GLU D 1 131 ? 38.967 -44.923 66.751 1.00 226.93 ? 131 GLU D OE1 1 +ATOM 6728 O OE2 . GLU D 1 131 ? 39.301 -46.969 66.007 1.00 165.04 ? 131 GLU D OE2 1 +ATOM 6729 N N . SER D 1 132 ? 34.812 -47.450 65.292 1.00 150.87 ? 132 SER D N 1 +ATOM 6730 C CA . SER D 1 132 ? 33.916 -48.526 64.897 1.00 135.68 ? 132 SER D CA 1 +ATOM 6731 C C . SER D 1 132 ? 34.427 -49.907 65.344 1.00 162.68 ? 132 SER D C 1 +ATOM 6732 O O . SER D 1 132 ? 35.632 -50.190 65.256 1.00 156.40 ? 132 SER D O 1 +ATOM 6733 C CB . SER D 1 132 ? 33.704 -48.485 63.385 1.00 113.41 ? 132 SER D CB 1 +ATOM 6734 O OG . SER D 1 132 ? 34.285 -49.616 62.762 1.00 96.68 ? 132 SER D OG 1 +ATOM 6735 N N . ASN D 1 133 ? 33.500 -50.761 65.791 1.00 151.19 ? 133 ASN D N 1 +ATOM 6736 C CA . ASN D 1 133 ? 33.844 -52.045 66.420 1.00 149.46 ? 133 ASN D CA 1 +ATOM 6737 C C . ASN D 1 133 ? 34.902 -51.874 67.497 1.00 156.18 ? 133 ASN D C 1 +ATOM 6738 O O . ASN D 1 133 ? 35.980 -52.473 67.445 1.00 105.03 ? 133 ASN D O 1 +ATOM 6739 C CB . ASN D 1 133 ? 34.321 -53.070 65.390 1.00 148.71 ? 133 ASN D CB 1 +ATOM 6740 C CG . ASN D 1 133 ? 33.259 -53.386 64.352 1.00 137.94 ? 133 ASN D CG 1 +ATOM 6741 O OD1 . ASN D 1 133 ? 32.055 -53.307 64.612 1.00 73.53 ? 133 ASN D OD1 1 +ATOM 6742 N ND2 . ASN D 1 133 ? 33.709 -53.742 63.158 1.00 140.73 ? 133 ASN D ND2 1 +ATOM 6743 N N . VAL D 1 134 ? 34.590 -50.997 68.443 1.00 180.79 ? 134 VAL D N 1 +ATOM 6744 C CA . VAL D 1 134 ? 35.487 -50.691 69.549 1.00 163.69 ? 134 VAL D CA 1 +ATOM 6745 C C . VAL D 1 134 ? 35.568 -51.950 70.391 1.00 157.87 ? 134 VAL D C 1 +ATOM 6746 O O . VAL D 1 134 ? 36.611 -52.275 70.953 1.00 126.31 ? 134 VAL D O 1 +ATOM 6747 C CB . VAL D 1 134 ? 34.963 -49.485 70.371 1.00 163.51 ? 134 VAL D CB 1 +ATOM 6748 C CG1 . VAL D 1 134 ? 35.921 -49.121 71.488 1.00 142.04 ? 134 VAL D CG1 1 +ATOM 6749 C CG2 . VAL D 1 134 ? 34.756 -48.274 69.460 1.00 223.27 ? 134 VAL D CG2 1 +ATOM 6750 N N . LYS D 1 135 ? 34.448 -52.663 70.467 1.00 191.49 ? 135 LYS D N 1 +ATOM 6751 C CA . LYS D 1 135 ? 34.457 -54.035 70.973 1.00 180.03 ? 135 LYS D CA 1 +ATOM 6752 C C . LYS D 1 135 ? 33.601 -54.937 70.102 1.00 177.05 ? 135 LYS D C 1 +ATOM 6753 O O . LYS D 1 135 ? 32.689 -54.476 69.386 1.00 238.36 ? 135 LYS D O 1 +ATOM 6754 C CB . LYS D 1 135 ? 33.938 -54.092 72.413 1.00 191.55 ? 135 LYS D CB 1 +ATOM 6755 C CG . LYS D 1 135 ? 34.799 -53.330 73.404 1.00 197.67 ? 135 LYS D CG 1 +ATOM 6756 C CD . LYS D 1 135 ? 34.163 -53.341 74.782 1.00 197.15 ? 135 LYS D CD 1 +ATOM 6757 C CE . LYS D 1 135 ? 34.991 -52.572 75.787 1.00 183.21 ? 135 LYS D CE 1 +ATOM 6758 N NZ . LYS D 1 135 ? 34.654 -52.997 77.168 1.00 171.78 ? 135 LYS D NZ 1 +ATOM 6759 N N . SER D 1 136 ? 33.868 -56.232 70.205 1.00 130.99 ? 136 SER D N 1 +ATOM 6760 C CA . SER D 1 136 ? 33.112 -57.218 69.462 1.00 119.86 ? 136 SER D CA 1 +ATOM 6761 C C . SER D 1 136 ? 33.319 -58.596 70.036 1.00 109.62 ? 136 SER D C 1 +ATOM 6762 O O . SER D 1 136 ? 34.333 -58.874 70.674 1.00 116.44 ? 136 SER D O 1 +ATOM 6763 C CB . SER D 1 136 ? 33.496 -57.186 67.975 1.00 141.46 ? 136 SER D CB 1 +ATOM 6764 O OG . SER D 1 136 ? 33.926 -58.461 67.513 1.00 138.70 ? 136 SER D OG 1 +ATOM 6765 N N . GLY D 1 137 ? 32.375 -59.483 69.763 1.00 127.78 ? 137 GLY D N 1 +ATOM 6766 C CA . GLY D 1 137 ? 32.490 -60.878 70.204 1.00 168.54 ? 137 GLY D CA 1 +ATOM 6767 C C . GLY D 1 137 ? 31.489 -61.812 69.549 1.00 181.70 ? 137 GLY D C 1 +ATOM 6768 O O . GLY D 1 137 ? 30.604 -61.364 68.815 1.00 265.37 ? 137 GLY D O 1 +ATOM 6769 N N . GLY D 1 138 ? 31.601 -63.104 69.842 1.00 135.40 ? 138 GLY D N 1 +ATOM 6770 C CA . GLY D 1 138 ? 30.671 -64.084 69.304 1.00 128.35 ? 138 GLY D CA 1 +ATOM 6771 C C . GLY D 1 138 ? 30.732 -65.410 70.019 1.00 147.84 ? 138 GLY D C 1 +ATOM 6772 O O . GLY D 1 138 ? 31.788 -65.820 70.498 1.00 157.51 ? 138 GLY D O 1 +ATOM 6773 N N . VAL D 1 139 ? 29.578 -66.065 70.132 1.00 180.58 ? 139 VAL D N 1 +ATOM 6774 C CA . VAL D 1 139 ? 29.489 -67.388 70.755 1.00 182.33 ? 139 VAL D CA 1 +ATOM 6775 C C . VAL D 1 139 ? 28.544 -68.280 69.963 1.00 181.95 ? 139 VAL D C 1 +ATOM 6776 O O . VAL D 1 139 ? 27.395 -67.909 69.706 1.00 191.23 ? 139 VAL D O 1 +ATOM 6777 C CB . VAL D 1 139 ? 28.973 -67.316 72.206 1.00 165.11 ? 139 VAL D CB 1 +ATOM 6778 C CG1 . VAL D 1 139 ? 28.773 -68.716 72.755 1.00 159.15 ? 139 VAL D CG1 1 +ATOM 6779 C CG2 . VAL D 1 139 ? 29.936 -66.529 73.082 1.00 173.92 ? 139 VAL D CG2 1 +ATOM 6780 N N . GLY D 1 140 ? 29.034 -69.455 69.576 1.00 178.62 ? 140 GLY D N 1 +ATOM 6781 C CA . GLY D 1 140 ? 28.250 -70.385 68.771 1.00 192.76 ? 140 GLY D CA 1 +ATOM 6782 C C . GLY D 1 140 ? 28.566 -71.846 69.040 1.00 187.89 ? 140 GLY D C 1 +ATOM 6783 O O . GLY D 1 140 ? 29.707 -72.207 69.311 1.00 190.98 ? 140 GLY D O 1 +ATOM 6784 N N . ALA D 1 141 ? 27.543 -72.690 68.956 1.00 178.99 ? 141 ALA D N 1 +ATOM 6785 C CA . ALA D 1 141 ? 27.696 -74.115 69.230 1.00 170.87 ? 141 ALA D CA 1 +ATOM 6786 C C . ALA D 1 141 ? 26.799 -74.974 68.335 1.00 175.86 ? 141 ALA D C 1 +ATOM 6787 O O . ALA D 1 141 ? 25.660 -74.601 68.020 1.00 161.54 ? 141 ALA D O 1 +ATOM 6788 C CB . ALA D 1 141 ? 27.414 -74.387 70.695 1.00 156.92 ? 141 ALA D CB 1 +ATOM 6789 N N . ARG D 1 142 ? 27.351 -76.086 67.871 1.00 179.19 ? 142 ARG D N 1 +ATOM 6790 C CA . ARG D 1 142 ? 26.599 -77.013 67.055 1.00 171.21 ? 142 ARG D CA 1 +ATOM 6791 C C . ARG D 1 142 ? 26.775 -78.418 67.613 1.00 200.63 ? 142 ARG D C 1 +ATOM 6792 O O . ARG D 1 142 ? 27.828 -78.757 68.146 1.00 206.45 ? 142 ARG D O 1 +ATOM 6793 C CB . ARG D 1 142 ? 27.046 -76.948 65.592 1.00 150.37 ? 142 ARG D CB 1 +ATOM 6794 C CG . ARG D 1 142 ? 26.218 -77.838 64.672 1.00 153.67 ? 142 ARG D CG 1 +ATOM 6795 C CD . ARG D 1 142 ? 25.886 -77.164 63.350 1.00 165.29 ? 142 ARG D CD 1 +ATOM 6796 N NE . ARG D 1 142 ? 26.987 -77.291 62.405 1.00 171.14 ? 142 ARG D NE 1 +ATOM 6797 C CZ . ARG D 1 142 ? 27.228 -76.455 61.402 1.00 210.79 ? 142 ARG D CZ 1 +ATOM 6798 N NH1 . ARG D 1 142 ? 26.466 -75.386 61.219 1.00 234.02 ? 142 ARG D NH1 1 +ATOM 6799 N NH2 . ARG D 1 142 ? 28.269 -76.662 60.603 1.00 236.82 ? 142 ARG D NH2 1 +ATOM 6800 N N . TYR D 1 143 ? 25.718 -79.219 67.519 1.00 207.64 ? 143 TYR D N 1 +ATOM 6801 C CA . TYR D 1 143 ? 25.671 -80.541 68.139 1.00 202.63 ? 143 TYR D CA 1 +ATOM 6802 C C . TYR D 1 143 ? 25.185 -81.604 67.151 1.00 176.84 ? 143 TYR D C 1 +ATOM 6803 O O . TYR D 1 143 ? 23.996 -81.940 67.096 1.00 185.24 ? 143 TYR D O 1 +ATOM 6804 C CB . TYR D 1 143 ? 24.764 -80.503 69.370 1.00 222.43 ? 143 TYR D CB 1 +ATOM 6805 C CG . TYR D 1 143 ? 24.748 -81.778 70.147 1.00 232.85 ? 143 TYR D CG 1 +ATOM 6806 C CD1 . TYR D 1 143 ? 25.846 -82.159 70.900 1.00 227.08 ? 143 TYR D CD1 1 +ATOM 6807 C CD2 . TYR D 1 143 ? 23.628 -82.601 70.144 1.00 218.03 ? 143 TYR D CD2 1 +ATOM 6808 C CE1 . TYR D 1 143 ? 25.826 -83.330 71.638 1.00 208.18 ? 143 TYR D CE1 1 +ATOM 6809 C CE2 . TYR D 1 143 ? 23.591 -83.770 70.889 1.00 184.58 ? 143 TYR D CE2 1 +ATOM 6810 C CZ . TYR D 1 143 ? 24.697 -84.134 71.626 1.00 180.80 ? 143 TYR D CZ 1 +ATOM 6811 O OH . TYR D 1 143 ? 24.682 -85.299 72.351 1.00 167.89 ? 143 TYR D OH 1 +ATOM 6812 N N . GLY D 1 145 ? 23.899 -81.980 64.798 1.00 142.86 ? 145 GLY D N 1 +ATOM 6813 C CA . GLY D 1 145 ? 23.076 -81.576 63.663 1.00 128.88 ? 145 GLY D CA 1 +ATOM 6814 C C . GLY D 1 145 ? 22.492 -80.193 63.816 1.00 131.82 ? 145 GLY D C 1 +ATOM 6815 O O . GLY D 1 145 ? 22.170 -79.546 62.818 1.00 129.96 ? 145 GLY D O 1 +ATOM 6816 N N . ILE D 1 146 ? 22.399 -79.713 65.054 1.00 155.16 ? 146 ILE D N 1 +ATOM 6817 C CA . ILE D 1 146 ? 21.697 -78.493 65.360 1.00 169.33 ? 146 ILE D CA 1 +ATOM 6818 C C . ILE D 1 146 ? 22.607 -77.453 65.969 1.00 181.89 ? 146 ILE D C 1 +ATOM 6819 O O . ILE D 1 146 ? 23.433 -77.784 66.796 1.00 178.31 ? 146 ILE D O 1 +ATOM 6820 C CB . ILE D 1 146 ? 20.622 -78.847 66.379 1.00 147.87 ? 146 ILE D CB 1 +ATOM 6821 C CG1 . ILE D 1 146 ? 19.952 -77.641 67.006 1.00 134.85 ? 146 ILE D CG1 1 +ATOM 6822 C CG2 . ILE D 1 146 ? 21.117 -79.850 67.426 1.00 140.01 ? 146 ILE D CG2 1 +ATOM 6823 C CD1 . ILE D 1 146 ? 18.468 -77.790 67.273 1.00 129.41 ? 146 ILE D CD1 1 +ATOM 6824 N N . GLY D 1 147 ? 22.430 -76.193 65.584 1.00 173.44 ? 147 GLY D N 1 +ATOM 6825 C CA . GLY D 1 147 ? 23.371 -75.166 65.988 1.00 157.41 ? 147 GLY D CA 1 +ATOM 6826 C C . GLY D 1 147 ? 22.799 -73.767 66.102 1.00 172.71 ? 147 GLY D C 1 +ATOM 6827 O O . GLY D 1 147 ? 21.793 -73.418 65.485 1.00 207.95 ? 147 GLY D O 1 +ATOM 6828 N N . ALA D 1 148 ? 23.455 -72.957 66.915 1.00 190.07 ? 148 ALA D N 1 +ATOM 6829 C CA . ALA D 1 148 ? 23.094 -71.558 67.049 1.00 184.28 ? 148 ALA D CA 1 +ATOM 6830 C C . ALA D 1 148 ? 24.341 -70.724 67.317 1.00 177.70 ? 148 ALA D C 1 +ATOM 6831 O O . ALA D 1 148 ? 25.414 -71.265 67.629 1.00 229.01 ? 148 ALA D O 1 +ATOM 6832 C CB . ALA D 1 148 ? 22.062 -71.383 68.156 1.00 156.85 ? 148 ALA D CB 1 +ATOM 6833 N N . ASP D 1 149 ? 24.201 -69.412 67.166 1.00 140.64 ? 149 ASP D N 1 +ATOM 6834 C CA . ASP D 1 149 ? 25.303 -68.503 67.453 1.00 139.74 ? 149 ASP D CA 1 +ATOM 6835 C C . ASP D 1 149 ? 24.808 -67.067 67.572 1.00 147.89 ? 149 ASP D C 1 +ATOM 6836 O O . ASP D 1 149 ? 23.816 -66.688 66.943 1.00 171.46 ? 149 ASP D O 1 +ATOM 6837 C CB . ASP D 1 149 ? 26.380 -68.616 66.372 1.00 135.18 ? 149 ASP D CB 1 +ATOM 6838 C CG . ASP D 1 149 ? 26.028 -67.865 65.136 1.00 140.61 ? 149 ASP D CG 1 +ATOM 6839 O OD1 . ASP D 1 149 ? 25.157 -68.346 64.386 1.00 152.13 ? 149 ASP D OD1 1 +ATOM 6840 O OD2 . ASP D 1 149 ? 26.608 -66.784 64.917 1.00 149.25 ? 149 ASP D OD2 1 +ATOM 6841 N N . THR D 1 150 ? 25.462 -66.285 68.423 1.00 163.47 ? 150 THR D N 1 +ATOM 6842 C CA . THR D 1 150 ? 25.274 -64.843 68.394 1.00 172.14 ? 150 THR D CA 1 +ATOM 6843 C C . THR D 1 150 ? 26.610 -64.158 68.150 1.00 186.37 ? 150 THR D C 1 +ATOM 6844 O O . THR D 1 150 ? 27.675 -64.714 68.439 1.00 225.21 ? 150 THR D O 1 +ATOM 6845 C CB . THR D 1 150 ? 24.647 -64.295 69.695 1.00 145.57 ? 150 THR D CB 1 +ATOM 6846 O OG1 . THR D 1 150 ? 25.487 -64.615 70.805 1.00 141.60 ? 150 THR D OG1 1 +ATOM 6847 C CG2 . THR D 1 150 ? 23.261 -64.863 69.911 1.00 124.66 ? 150 THR D CG2 1 +ATOM 6848 N N . GLN D 1 151 ? 26.539 -62.959 67.592 1.00 148.61 ? 151 GLN D N 1 +ATOM 6849 C CA . GLN D 1 151 ? 27.693 -62.115 67.418 1.00 114.67 ? 151 GLN D CA 1 +ATOM 6850 C C . GLN D 1 151 ? 27.300 -60.708 67.792 1.00 111.78 ? 151 GLN D C 1 +ATOM 6851 O O . GLN D 1 151 ? 26.191 -60.291 67.539 1.00 106.18 ? 151 GLN D O 1 +ATOM 6852 C CB . GLN D 1 151 ? 28.144 -62.186 65.971 1.00 116.97 ? 151 GLN D CB 1 +ATOM 6853 C CG . GLN D 1 151 ? 28.793 -63.509 65.629 1.00 141.18 ? 151 GLN D CG 1 +ATOM 6854 C CD . GLN D 1 151 ? 28.758 -63.792 64.147 1.00 165.07 ? 151 GLN D CD 1 +ATOM 6855 O OE1 . GLN D 1 151 ? 28.985 -62.893 63.342 1.00 186.26 ? 151 GLN D OE1 1 +ATOM 6856 N NE2 . GLN D 1 151 ? 28.489 -65.044 63.776 1.00 168.45 ? 151 GLN D NE2 1 +ATOM 6857 N N . TYR D 1 152 ? 28.202 -59.973 68.419 1.00 134.00 ? 152 TYR D N 1 +ATOM 6858 C CA . TYR D 1 152 ? 27.910 -58.582 68.740 1.00 137.46 ? 152 TYR D CA 1 +ATOM 6859 C C . TYR D 1 152 ? 29.084 -57.657 68.429 1.00 153.89 ? 152 TYR D C 1 +ATOM 6860 O O . TYR D 1 152 ? 30.246 -58.069 68.511 1.00 176.72 ? 152 TYR D O 1 +ATOM 6861 C CB . TYR D 1 152 ? 27.490 -58.452 70.192 1.00 105.36 ? 152 TYR D CB 1 +ATOM 6862 C CG . TYR D 1 152 ? 28.534 -57.860 71.133 1.00 114.55 ? 152 TYR D CG 1 +ATOM 6863 C CD1 . TYR D 1 152 ? 29.764 -58.509 71.388 1.00 89.22 ? 152 TYR D CD1 1 +ATOM 6864 C CD2 . TYR D 1 152 ? 28.268 -56.685 71.817 1.00 108.64 ? 152 TYR D CD2 1 +ATOM 6865 C CE1 . TYR D 1 152 ? 30.717 -57.966 72.244 1.00 68.12 ? 152 TYR D CE1 1 +ATOM 6866 C CE2 . TYR D 1 152 ? 29.174 -56.178 72.741 1.00 103.65 ? 152 TYR D CE2 1 +ATOM 6867 C CZ . TYR D 1 152 ? 30.392 -56.823 72.954 1.00 86.26 ? 152 TYR D CZ 1 +ATOM 6868 O OH . TYR D 1 152 ? 31.240 -56.341 73.909 1.00 80.43 ? 152 TYR D OH 1 +ATOM 6869 N N . GLN D 1 153 ? 28.772 -56.436 67.995 1.00 121.25 ? 153 GLN D N 1 +ATOM 6870 C CA . GLN D 1 153 ? 29.783 -55.413 67.843 1.00 95.95 ? 153 GLN D CA 1 +ATOM 6871 C C . GLN D 1 153 ? 29.279 -54.120 68.457 1.00 106.75 ? 153 GLN D C 1 +ATOM 6872 O O . GLN D 1 153 ? 28.065 -53.882 68.549 1.00 125.35 ? 153 GLN D O 1 +ATOM 6873 C CB . GLN D 1 153 ? 30.115 -55.215 66.360 1.00 102.05 ? 153 GLN D CB 1 +ATOM 6874 C CG . GLN D 1 153 ? 30.782 -56.423 65.713 1.00 114.30 ? 153 GLN D CG 1 +ATOM 6875 C CD . GLN D 1 153 ? 29.818 -57.554 65.278 1.00 110.22 ? 153 GLN D CD 1 +ATOM 6876 O OE1 . GLN D 1 153 ? 28.596 -57.415 65.351 1.00 85.59 ? 153 GLN D OE1 1 +ATOM 6877 N NE2 . GLN D 1 153 ? 30.379 -58.634 64.737 1.00 111.17 ? 153 GLN D NE2 1 +ATOM 6878 N N . LEU D 1 154 ? 30.205 -53.267 68.881 1.00 125.89 ? 154 LEU D N 1 +ATOM 6879 C CA . LEU D 1 154 ? 29.816 -51.930 69.340 1.00 141.32 ? 154 LEU D CA 1 +ATOM 6880 C C . LEU D 1 154 ? 30.832 -50.842 68.973 1.00 134.86 ? 154 LEU D C 1 +ATOM 6881 O O . LEU D 1 154 ? 32.049 -51.068 69.026 1.00 118.51 ? 154 LEU D O 1 +ATOM 6882 C CB . LEU D 1 154 ? 29.540 -51.931 70.851 1.00 135.22 ? 154 LEU D CB 1 +ATOM 6883 C CG . LEU D 1 154 ? 30.770 -52.069 71.760 1.00 173.02 ? 154 LEU D CG 1 +ATOM 6884 C CD1 . LEU D 1 154 ? 31.282 -50.711 72.213 1.00 161.90 ? 154 LEU D CD1 1 +ATOM 6885 C CD2 . LEU D 1 154 ? 30.433 -52.954 72.950 1.00 208.14 ? 154 LEU D CD2 1 +ATOM 6886 N N . ASP D 1 155 ? 30.286 -49.645 68.738 1.00 123.15 ? 155 ASP D N 1 +ATOM 6887 C CA . ASP D 1 155 ? 30.995 -48.496 68.189 1.00 93.44 ? 155 ASP D CA 1 +ATOM 6888 C C . ASP D 1 155 ? 30.837 -47.313 69.133 1.00 99.23 ? 155 ASP D C 1 +ATOM 6889 O O . ASP D 1 155 ? 30.000 -47.339 70.049 1.00 87.56 ? 155 ASP D O 1 +ATOM 6890 C CB . ASP D 1 155 ? 30.384 -48.100 66.861 1.00 101.04 ? 155 ASP D CB 1 +ATOM 6891 C CG . ASP D 1 155 ? 30.158 -49.292 65.955 1.00 143.31 ? 155 ASP D CG 1 +ATOM 6892 O OD1 . ASP D 1 155 ? 29.136 -50.007 66.137 1.00 212.05 ? 155 ASP D OD1 1 +ATOM 6893 O OD2 . ASP D 1 155 ? 30.972 -49.503 65.035 1.00 129.58 ? 155 ASP D OD2 1 +ATOM 6894 N N . GLN D 1 156 ? 31.724 -46.327 69.006 1.00 130.20 ? 156 GLN D N 1 +ATOM 6895 C CA . GLN D 1 156 ? 31.727 -45.179 69.941 1.00 142.54 ? 156 GLN D CA 1 +ATOM 6896 C C . GLN D 1 156 ? 31.446 -43.890 69.206 1.00 129.12 ? 156 GLN D C 1 +ATOM 6897 O O . GLN D 1 156 ? 31.654 -43.805 68.004 1.00 116.24 ? 156 GLN D O 1 +ATOM 6898 C CB . GLN D 1 156 ? 33.066 -45.059 70.689 1.00 142.26 ? 156 GLN D CB 1 +ATOM 6899 C CG . GLN D 1 156 ? 33.050 -44.071 71.843 1.00 130.29 ? 156 GLN D CG 1 +ATOM 6900 C CD . GLN D 1 156 ? 34.164 -44.326 72.848 1.00 147.99 ? 156 GLN D CD 1 +ATOM 6901 O OE1 . GLN D 1 156 ? 35.074 -45.135 72.615 1.00 133.46 ? 156 GLN D OE1 1 +ATOM 6902 N NE2 . GLN D 1 156 ? 34.098 -43.632 73.981 1.00 168.27 ? 156 GLN D NE2 1 +ATOM 6903 N N . ILE D 1 157 ? 30.904 -42.917 69.921 1.00 115.68 ? 157 ILE D N 1 +ATOM 6904 C CA . ILE D 1 157 ? 30.643 -41.615 69.346 1.00 124.74 ? 157 ILE D CA 1 +ATOM 6905 C C . ILE D 1 157 ? 30.781 -40.591 70.474 1.00 142.22 ? 157 ILE D C 1 +ATOM 6906 O O . ILE D 1 157 ? 30.326 -40.824 71.603 1.00 176.02 ? 157 ILE D O 1 +ATOM 6907 C CB . ILE D 1 157 ? 29.246 -41.571 68.681 1.00 134.75 ? 157 ILE D CB 1 +ATOM 6908 C CG1 . ILE D 1 157 ? 29.178 -40.486 67.609 1.00 118.55 ? 157 ILE D CG1 1 +ATOM 6909 C CG2 . ILE D 1 157 ? 28.149 -41.347 69.723 1.00 165.67 ? 157 ILE D CG2 1 +ATOM 6910 C CD1 . ILE D 1 157 ? 27.899 -40.500 66.782 1.00 100.17 ? 157 ILE D CD1 1 +ATOM 6911 N N . ALA D 1 158 ? 31.420 -39.464 70.192 1.00 123.03 ? 158 ALA D N 1 +ATOM 6912 C CA . ALA D 1 158 ? 31.588 -38.453 71.226 1.00 100.58 ? 158 ALA D CA 1 +ATOM 6913 C C . ALA D 1 158 ? 31.196 -37.083 70.705 1.00 84.17 ? 158 ALA D C 1 +ATOM 6914 O O . ALA D 1 158 ? 31.302 -36.819 69.504 1.00 90.11 ? 158 ALA D O 1 +ATOM 6915 C CB . ALA D 1 158 ? 33.014 -38.473 71.751 1.00 77.49 ? 158 ALA D CB 1 +ATOM 6916 N N . VAL D 1 159 ? 30.736 -36.232 71.614 1.00 60.66 ? 159 VAL D N 1 +ATOM 6917 C CA . VAL D 1 159 ? 30.268 -34.924 71.241 1.00 75.43 ? 159 VAL D CA 1 +ATOM 6918 C C . VAL D 1 159 ? 30.715 -33.832 72.200 1.00 85.00 ? 159 VAL D C 1 +ATOM 6919 O O . VAL D 1 159 ? 30.712 -34.002 73.425 1.00 134.98 ? 159 VAL D O 1 +ATOM 6920 C CB . VAL D 1 159 ? 28.751 -34.903 71.198 1.00 108.17 ? 159 VAL D CB 1 +ATOM 6921 C CG1 . VAL D 1 159 ? 28.225 -33.478 71.302 1.00 132.35 ? 159 VAL D CG1 1 +ATOM 6922 C CG2 . VAL D 1 159 ? 28.255 -35.548 69.923 1.00 135.86 ? 159 VAL D CG2 1 +ATOM 6923 N N . ASN D 1 160 ? 31.256 -32.752 71.628 1.00 101.09 ? 160 ASN D N 1 +ATOM 6924 C CA . ASN D 1 160 ? 31.703 -31.571 72.406 1.00 100.06 ? 160 ASN D CA 1 +ATOM 6925 C C . ASN D 1 160 ? 30.653 -30.524 72.242 1.00 102.60 ? 160 ASN D C 1 +ATOM 6926 O O . ASN D 1 160 ? 30.170 -30.319 71.122 1.00 128.65 ? 160 ASN D O 1 +ATOM 6927 C CB . ASN D 1 160 ? 33.050 -31.027 71.864 1.00 105.03 ? 160 ASN D CB 1 +ATOM 6928 C CG . ASN D 1 160 ? 33.482 -29.702 72.495 1.00 101.96 ? 160 ASN D CG 1 +ATOM 6929 O OD1 . ASN D 1 160 ? 32.697 -28.787 72.695 1.00 85.75 ? 160 ASN D OD1 1 +ATOM 6930 N ND2 . ASN D 1 160 ? 34.761 -29.620 72.835 1.00 111.23 ? 160 ASN D ND2 1 +ATOM 6931 N N . LEU D 1 161 ? 30.148 -30.037 73.364 1.00 86.96 ? 161 LEU D N 1 +ATOM 6932 C CA . LEU D 1 161 ? 29.382 -28.814 73.346 1.00 78.84 ? 161 LEU D CA 1 +ATOM 6933 C C . LEU D 1 161 ? 30.067 -27.801 74.229 1.00 78.79 ? 161 LEU D C 1 +ATOM 6934 O O . LEU D 1 161 ? 30.636 -28.125 75.257 1.00 74.39 ? 161 LEU D O 1 +ATOM 6935 C CB . LEU D 1 161 ? 27.962 -29.063 73.824 1.00 75.15 ? 161 LEU D CB 1 +ATOM 6936 C CG . LEU D 1 161 ? 27.131 -29.983 72.948 1.00 87.67 ? 161 LEU D CG 1 +ATOM 6937 C CD1 . LEU D 1 161 ? 25.817 -30.304 73.634 1.00 103.16 ? 161 LEU D CD1 1 +ATOM 6938 C CD2 . LEU D 1 161 ? 26.893 -29.320 71.594 1.00 104.84 ? 161 LEU D CD2 1 +ATOM 6939 N N . ARG D 1 162 ? 29.958 -26.535 73.878 1.00 102.95 ? 162 ARG D N 1 +ATOM 6940 C CA . ARG D 1 162 ? 30.579 -25.494 74.702 1.00 111.41 ? 162 ARG D CA 1 +ATOM 6941 C C . ARG D 1 162 ? 29.904 -24.106 74.607 1.00 102.39 ? 162 ARG D C 1 +ATOM 6942 O O . ARG D 1 162 ? 29.587 -23.624 73.524 1.00 84.22 ? 162 ARG D O 1 +ATOM 6943 C CB . ARG D 1 162 ? 32.079 -25.408 74.412 1.00 98.17 ? 162 ARG D CB 1 +ATOM 6944 C CG . ARG D 1 162 ? 32.459 -24.993 73.007 1.00 116.80 ? 162 ARG D CG 1 +ATOM 6945 C CD . ARG D 1 162 ? 33.910 -24.553 72.976 1.00 107.75 ? 162 ARG D CD 1 +ATOM 6946 N NE . ARG D 1 162 ? 34.285 -23.949 71.682 1.00 112.20 ? 162 ARG D NE 1 +ATOM 6947 C CZ . ARG D 1 162 ? 34.598 -24.612 70.570 1.00 85.16 ? 162 ARG D CZ 1 +ATOM 6948 N NH1 . ARG D 1 162 ? 34.588 -25.939 70.582 1.00 100.47 ? 162 ARG D NH1 1 +ATOM 6949 N NH2 . ARG D 1 162 ? 34.894 -23.939 69.448 1.00 61.27 ? 162 ARG D NH2 1 +ATOM 6950 N N . VAL D 1 163 ? 29.660 -23.515 75.776 1.00 98.51 ? 163 VAL D N 1 +ATOM 6951 C CA . VAL D 1 163 ? 29.013 -22.206 75.895 1.00 90.51 ? 163 VAL D CA 1 +ATOM 6952 C C . VAL D 1 163 ? 30.050 -21.141 75.812 1.00 92.08 ? 163 VAL D C 1 +ATOM 6953 O O . VAL D 1 163 ? 30.991 -21.107 76.624 1.00 159.70 ? 163 VAL D O 1 +ATOM 6954 C CB . VAL D 1 163 ? 28.344 -22.012 77.267 1.00 102.49 ? 163 VAL D CB 1 +ATOM 6955 C CG1 . VAL D 1 163 ? 27.751 -20.608 77.363 1.00 73.30 ? 163 VAL D CG1 1 +ATOM 6956 C CG2 . VAL D 1 163 ? 27.305 -23.111 77.511 1.00 125.24 ? 163 VAL D CG2 1 +ATOM 6957 N N . VAL D 1 164 ? 29.860 -20.251 74.862 1.00 87.91 ? 164 VAL D N 1 +ATOM 6958 C CA . VAL D 1 164 ? 30.772 -19.139 74.638 1.00 115.69 ? 164 VAL D CA 1 +ATOM 6959 C C . VAL D 1 164 ? 30.051 -17.846 74.955 1.00 100.34 ? 164 VAL D C 1 +ATOM 6960 O O . VAL D 1 164 ? 28.896 -17.669 74.557 1.00 94.97 ? 164 VAL D O 1 +ATOM 6961 C CB . VAL D 1 164 ? 31.229 -19.060 73.178 1.00 138.68 ? 164 VAL D CB 1 +ATOM 6962 C CG1 . VAL D 1 164 ? 32.127 -17.857 72.969 1.00 144.11 ? 164 VAL D CG1 1 +ATOM 6963 C CG2 . VAL D 1 164 ? 31.963 -20.321 72.803 1.00 148.00 ? 164 VAL D CG2 1 +ATOM 6964 N N . ASN D 1 165 ? 30.743 -16.955 75.664 1.00 71.75 ? 165 ASN D N 1 +ATOM 6965 C CA . ASN D 1 165 ? 30.156 -15.690 76.036 1.00 61.39 ? 165 ASN D CA 1 +ATOM 6966 C C . ASN D 1 165 ? 30.365 -14.669 74.949 1.00 75.52 ? 165 ASN D C 1 +ATOM 6967 O O . ASN D 1 165 ? 31.508 -14.355 74.600 1.00 98.40 ? 165 ASN D O 1 +ATOM 6968 C CB . ASN D 1 165 ? 30.767 -15.163 77.312 1.00 60.30 ? 165 ASN D CB 1 +ATOM 6969 C CG . ASN D 1 165 ? 30.034 -13.946 77.813 1.00 71.08 ? 165 ASN D CG 1 +ATOM 6970 O OD1 . ASN D 1 165 ? 28.941 -13.608 77.333 1.00 44.98 ? 165 ASN D OD1 1 +ATOM 6971 N ND2 . ASN D 1 165 ? 30.623 -13.266 78.779 1.00 93.95 ? 165 ASN D ND2 1 +ATOM 6972 N N . VAL D 1 166 ? 29.262 -14.153 74.400 1.00 84.70 ? 166 VAL D N 1 +ATOM 6973 C CA . VAL D 1 166 ? 29.298 -13.230 73.252 1.00 71.26 ? 166 VAL D CA 1 +ATOM 6974 C C . VAL D 1 166 ? 30.015 -11.971 73.623 1.00 71.67 ? 166 VAL D C 1 +ATOM 6975 O O . VAL D 1 166 ? 30.808 -11.470 72.854 1.00 71.32 ? 166 VAL D O 1 +ATOM 6976 C CB . VAL D 1 166 ? 27.879 -12.861 72.793 1.00 77.86 ? 166 VAL D CB 1 +ATOM 6977 C CG1 . VAL D 1 166 ? 27.842 -11.516 72.094 1.00 63.31 ? 166 VAL D CG1 1 +ATOM 6978 C CG2 . VAL D 1 166 ? 27.310 -13.991 71.909 1.00 119.00 ? 166 VAL D CG2 1 +ATOM 6979 N N . SER D 1 167 ? 29.808 -11.539 74.860 1.00 85.18 ? 167 SER D N 1 +ATOM 6980 C CA . SER D 1 167 ? 30.330 -10.266 75.324 1.00 89.75 ? 167 SER D CA 1 +ATOM 6981 C C . SER D 1 167 ? 31.847 -10.268 75.501 1.00 88.46 ? 167 SER D C 1 +ATOM 6982 O O . SER D 1 167 ? 32.442 -9.201 75.642 1.00 89.45 ? 167 SER D O 1 +ATOM 6983 C CB . SER D 1 167 ? 29.631 -9.876 76.624 1.00 98.00 ? 167 SER D CB 1 +ATOM 6984 O OG . SER D 1 167 ? 28.227 -10.105 76.520 1.00 151.03 ? 167 SER D OG 1 +ATOM 6985 N N . THR D 1 168 ? 32.477 -11.450 75.492 1.00 84.99 ? 168 THR D N 1 +ATOM 6986 C CA . THR D 1 168 ? 33.923 -11.550 75.731 1.00 90.16 ? 168 THR D CA 1 +ATOM 6987 C C . THR D 1 168 ? 34.665 -12.521 74.798 1.00 76.78 ? 168 THR D C 1 +ATOM 6988 O O . THR D 1 168 ? 35.852 -12.363 74.506 1.00 63.22 ? 168 THR D O 1 +ATOM 6989 C CB . THR D 1 168 ? 34.219 -11.949 77.196 1.00 103.95 ? 168 THR D CB 1 +ATOM 6990 O OG1 . THR D 1 168 ? 33.473 -13.128 77.540 1.00 117.01 ? 168 THR D OG1 1 +ATOM 6991 C CG2 . THR D 1 168 ? 33.862 -10.806 78.159 1.00 103.40 ? 168 THR D CG2 1 +ATOM 6992 N N . GLY D 1 169 ? 34.011 -13.603 74.455 1.00 70.49 ? 169 GLY D N 1 +ATOM 6993 C CA . GLY D 1 169 ? 34.722 -14.667 73.798 1.00 79.75 ? 169 GLY D CA 1 +ATOM 6994 C C . GLY D 1 169 ? 35.305 -15.684 74.755 1.00 108.92 ? 169 GLY D C 1 +ATOM 6995 O O . GLY D 1 169 ? 35.662 -16.793 74.334 1.00 182.60 ? 169 GLY D O 1 +ATOM 6996 N N . GLU D 1 170 ? 35.254 -15.400 76.056 1.00 121.48 ? 170 GLU D N 1 +ATOM 6997 C CA . GLU D 1 170 ? 35.472 -16.438 77.071 1.00 133.92 ? 170 GLU D CA 1 +ATOM 6998 C C . GLU D 1 170 ? 34.525 -17.613 76.829 1.00 128.07 ? 170 GLU D C 1 +ATOM 6999 O O . GLU D 1 170 ? 33.332 -17.446 76.710 1.00 73.58 ? 170 GLU D O 1 +ATOM 7000 C CB . GLU D 1 170 ? 35.253 -15.910 78.505 1.00 141.96 ? 170 GLU D CB 1 +ATOM 7001 C CG . GLU D 1 170 ? 36.381 -15.021 79.028 1.00 150.11 ? 170 GLU D CG 1 +ATOM 7002 C CD . GLU D 1 170 ? 35.916 -13.866 79.906 1.00 151.66 ? 170 GLU D CD 1 +ATOM 7003 O OE1 . GLU D 1 170 ? 34.695 -13.604 79.956 1.00 160.51 ? 170 GLU D OE1 1 +ATOM 7004 O OE2 . GLU D 1 170 ? 36.777 -13.170 80.487 1.00 145.65 ? 170 GLU D OE2 1 +ATOM 7005 N N . ILE D 1 171 ? 35.073 -18.815 76.733 1.00 141.59 ? 171 ILE D N 1 +ATOM 7006 C CA . ILE D 1 171 ? 34.257 -20.001 76.835 1.00 135.51 ? 171 ILE D CA 1 +ATOM 7007 C C . ILE D 1 171 ? 33.808 -20.156 78.295 1.00 132.97 ? 171 ILE D C 1 +ATOM 7008 O O . ILE D 1 171 ? 34.628 -20.144 79.200 1.00 114.89 ? 171 ILE D O 1 +ATOM 7009 C CB . ILE D 1 171 ? 35.037 -21.236 76.388 1.00 128.51 ? 171 ILE D CB 1 +ATOM 7010 C CG1 . ILE D 1 171 ? 35.255 -21.166 74.882 1.00 115.91 ? 171 ILE D CG1 1 +ATOM 7011 C CG2 . ILE D 1 171 ? 34.288 -22.498 76.790 1.00 140.30 ? 171 ILE D CG2 1 +ATOM 7012 C CD1 . ILE D 1 171 ? 36.331 -22.118 74.409 1.00 135.89 ? 171 ILE D CD1 1 +ATOM 7013 N N . LEU D 1 172 ? 32.503 -20.243 78.518 1.00 113.90 ? 172 LEU D N 1 +ATOM 7014 C CA . LEU D 1 172 ? 31.976 -20.311 79.873 1.00 90.84 ? 172 LEU D CA 1 +ATOM 7015 C C . LEU D 1 172 ? 31.765 -21.760 80.346 1.00 100.87 ? 172 LEU D C 1 +ATOM 7016 O O . LEU D 1 172 ? 31.555 -22.040 81.549 1.00 89.04 ? 172 LEU D O 1 +ATOM 7017 C CB . LEU D 1 172 ? 30.669 -19.547 79.977 1.00 97.03 ? 172 LEU D CB 1 +ATOM 7018 C CG . LEU D 1 172 ? 30.815 -18.008 79.868 1.00 107.84 ? 172 LEU D CG 1 +ATOM 7019 C CD1 . LEU D 1 172 ? 29.533 -17.170 80.112 1.00 122.86 ? 172 LEU D CD1 1 +ATOM 7020 C CD2 . LEU D 1 172 ? 31.981 -17.464 80.668 1.00 85.86 ? 172 LEU D CD2 1 +ATOM 7021 N N . SER D 1 173 ? 31.850 -22.692 79.404 1.00 91.83 ? 173 SER D N 1 +ATOM 7022 C CA . SER D 1 173 ? 31.721 -24.097 79.724 1.00 105.32 ? 173 SER D CA 1 +ATOM 7023 C C . SER D 1 173 ? 32.088 -24.947 78.519 1.00 108.15 ? 173 SER D C 1 +ATOM 7024 O O . SER D 1 173 ? 31.545 -24.767 77.430 1.00 126.35 ? 173 SER D O 1 +ATOM 7025 C CB . SER D 1 173 ? 30.280 -24.409 80.160 1.00 123.99 ? 173 SER D CB 1 +ATOM 7026 O OG . SER D 1 173 ? 30.027 -25.815 80.139 1.00 160.48 ? 173 SER D OG 1 +ATOM 7027 N N . SER D 1 174 ? 32.884 -25.978 78.746 1.00 117.65 ? 174 SER D N 1 +ATOM 7028 C CA . SER D 1 174 ? 33.055 -27.041 77.746 1.00 140.63 ? 174 SER D CA 1 +ATOM 7029 C C . SER D 1 174 ? 32.666 -28.382 78.356 1.00 139.70 ? 174 SER D C 1 +ATOM 7030 O O . SER D 1 174 ? 33.054 -28.689 79.486 1.00 211.76 ? 174 SER D O 1 +ATOM 7031 C CB . SER D 1 174 ? 34.513 -27.084 77.251 1.00 147.58 ? 174 SER D CB 1 +ATOM 7032 O OG . SER D 1 174 ? 34.691 -27.925 76.117 1.00 119.68 ? 174 SER D OG 1 +ATOM 7033 N N . VAL D 1 175 ? 31.949 -29.202 77.590 1.00 115.75 ? 175 VAL D N 1 +ATOM 7034 C CA . VAL D 1 175 ? 31.585 -30.552 78.032 1.00 107.98 ? 175 VAL D CA 1 +ATOM 7035 C C . VAL D 1 175 ? 31.764 -31.610 76.941 1.00 104.02 ? 175 VAL D C 1 +ATOM 7036 O O . VAL D 1 175 ? 31.584 -31.336 75.744 1.00 109.40 ? 175 VAL D O 1 +ATOM 7037 C CB . VAL D 1 175 ? 30.127 -30.596 78.507 1.00 121.71 ? 175 VAL D CB 1 +ATOM 7038 C CG1 . VAL D 1 175 ? 29.937 -29.689 79.707 1.00 118.70 ? 175 VAL D CG1 1 +ATOM 7039 C CG2 . VAL D 1 175 ? 29.186 -30.178 77.399 1.00 133.45 ? 175 VAL D CG2 1 +ATOM 7040 N N . ASN D 1 176 ? 32.155 -32.817 77.353 1.00 100.82 ? 176 ASN D N 1 +ATOM 7041 C CA . ASN D 1 176 ? 32.564 -33.885 76.413 1.00 108.83 ? 176 ASN D CA 1 +ATOM 7042 C C . ASN D 1 176 ? 31.796 -35.178 76.677 1.00 71.66 ? 176 ASN D C 1 +ATOM 7043 O O . ASN D 1 176 ? 32.233 -35.981 77.470 1.00 83.38 ? 176 ASN D O 1 +ATOM 7044 C CB . ASN D 1 176 ? 34.086 -34.147 76.555 1.00 109.39 ? 176 ASN D CB 1 +ATOM 7045 C CG . ASN D 1 176 ? 34.941 -33.435 75.493 1.00 116.82 ? 176 ASN D CG 1 +ATOM 7046 O OD1 . ASN D 1 176 ? 36.145 -33.729 75.285 1.00 127.65 ? 176 ASN D OD1 1 +ATOM 7047 N ND2 . ASN D 1 176 ? 34.319 -32.495 74.812 1.00 114.32 ? 176 ASN D ND2 1 +ATOM 7048 N N . THR D 1 177 ? 30.683 -35.395 75.985 1.00 72.46 ? 177 THR D N 1 +ATOM 7049 C CA . THR D 1 177 ? 29.857 -36.592 76.197 1.00 81.62 ? 177 THR D CA 1 +ATOM 7050 C C . THR D 1 177 ? 30.222 -37.705 75.218 1.00 96.40 ? 177 THR D C 1 +ATOM 7051 O O . THR D 1 177 ? 30.768 -37.445 74.139 1.00 122.65 ? 177 THR D O 1 +ATOM 7052 C CB . THR D 1 177 ? 28.342 -36.271 76.101 1.00 82.92 ? 177 THR D CB 1 +ATOM 7053 O OG1 . THR D 1 177 ? 27.998 -35.955 74.752 1.00 79.05 ? 177 THR D OG1 1 +ATOM 7054 C CG2 . THR D 1 177 ? 27.986 -35.084 76.984 1.00 93.53 ? 177 THR D CG2 1 +ATOM 7055 N N . SER D 1 178 ? 29.846 -38.932 75.567 1.00 111.57 ? 178 SER D N 1 +ATOM 7056 C CA . SER D 1 178 ? 30.141 -40.108 74.736 1.00 130.38 ? 178 SER D CA 1 +ATOM 7057 C C . SER D 1 178 ? 29.037 -41.166 74.831 1.00 139.17 ? 178 SER D C 1 +ATOM 7058 O O . SER D 1 178 ? 28.296 -41.235 75.808 1.00 103.33 ? 178 SER D O 1 +ATOM 7059 C CB . SER D 1 178 ? 31.462 -40.741 75.154 1.00 122.54 ? 178 SER D CB 1 +ATOM 7060 O OG . SER D 1 178 ? 31.607 -42.041 74.590 1.00 97.93 ? 178 SER D OG 1 +ATOM 7061 N N . LYS D 1 179 ? 28.923 -41.986 73.792 1.00 147.92 ? 179 LYS D N 1 +ATOM 7062 C CA . LYS D 1 179 ? 27.809 -42.918 73.701 1.00 128.36 ? 179 LYS D CA 1 +ATOM 7063 C C . LYS D 1 179 ? 28.193 -44.098 72.808 1.00 121.65 ? 179 LYS D C 1 +ATOM 7064 O O . LYS D 1 179 ? 28.911 -43.954 71.815 1.00 89.73 ? 179 LYS D O 1 +ATOM 7065 C CB . LYS D 1 179 ? 26.560 -42.199 73.175 1.00 103.17 ? 179 LYS D CB 1 +ATOM 7066 C CG . LYS D 1 179 ? 25.259 -42.656 73.778 1.00 87.51 ? 179 LYS D CG 1 +ATOM 7067 C CD . LYS D 1 179 ? 24.635 -43.724 72.914 1.00 98.91 ? 179 LYS D CD 1 +ATOM 7068 C CE . LYS D 1 179 ? 23.425 -44.321 73.600 1.00 127.97 ? 179 LYS D CE 1 +ATOM 7069 N NZ . LYS D 1 179 ? 22.976 -45.571 72.931 1.00 144.16 ? 179 LYS D NZ 1 +ATOM 7070 N N . THR D 1 180 ? 27.706 -45.269 73.190 1.00 116.81 ? 180 THR D N 1 +ATOM 7071 C CA . THR D 1 180 ? 28.061 -46.495 72.516 1.00 132.05 ? 180 THR D CA 1 +ATOM 7072 C C . THR D 1 180 ? 26.890 -47.031 71.664 1.00 167.74 ? 180 THR D C 1 +ATOM 7073 O O . THR D 1 180 ? 25.731 -47.076 72.111 1.00 92.17 ? 180 THR D O 1 +ATOM 7074 C CB . THR D 1 180 ? 28.538 -47.575 73.508 1.00 136.60 ? 180 THR D CB 1 +ATOM 7075 O OG1 . THR D 1 180 ? 28.335 -48.868 72.922 1.00 170.25 ? 180 THR D OG1 1 +ATOM 7076 C CG2 . THR D 1 180 ? 27.790 -47.479 74.830 1.00 122.50 ? 180 THR D CG2 1 +ATOM 7077 N N . ILE D 1 181 ? 27.202 -47.389 70.416 1.00 193.62 ? 181 ILE D N 1 +ATOM 7078 C CA . ILE D 1 181 ? 26.201 -47.928 69.490 1.00 171.19 ? 181 ILE D CA 1 +ATOM 7079 C C . ILE D 1 181 ? 26.293 -49.454 69.449 1.00 142.35 ? 181 ILE D C 1 +ATOM 7080 O O . ILE D 1 181 ? 27.319 -50.011 69.032 1.00 117.57 ? 181 ILE D O 1 +ATOM 7081 C CB . ILE D 1 181 ? 26.377 -47.338 68.069 1.00 172.48 ? 181 ILE D CB 1 +ATOM 7082 C CG1 . ILE D 1 181 ? 26.396 -45.807 68.123 1.00 181.54 ? 181 ILE D CG1 1 +ATOM 7083 C CG2 . ILE D 1 181 ? 25.258 -47.776 67.138 1.00 173.92 ? 181 ILE D CG2 1 +ATOM 7084 C CD1 . ILE D 1 181 ? 27.684 -45.204 67.614 1.00 218.30 ? 181 ILE D CD1 1 +ATOM 7085 N N . LEU D 1 182 ? 25.219 -50.114 69.879 1.00 116.31 ? 182 LEU D N 1 +ATOM 7086 C CA . LEU D 1 182 ? 25.164 -51.585 69.946 1.00 122.64 ? 182 LEU D CA 1 +ATOM 7087 C C . LEU D 1 182 ? 24.595 -52.289 68.696 1.00 96.64 ? 182 LEU D C 1 +ATOM 7088 O O . LEU D 1 182 ? 23.613 -51.819 68.102 1.00 108.05 ? 182 LEU D O 1 +ATOM 7089 C CB . LEU D 1 182 ? 24.319 -52.006 71.135 1.00 120.71 ? 182 LEU D CB 1 +ATOM 7090 C CG . LEU D 1 182 ? 24.166 -53.516 71.324 1.00 128.14 ? 182 LEU D CG 1 +ATOM 7091 C CD1 . LEU D 1 182 ? 25.495 -54.227 71.585 1.00 133.17 ? 182 LEU D CD1 1 +ATOM 7092 C CD2 . LEU D 1 182 ? 23.183 -53.746 72.459 1.00 143.23 ? 182 LEU D CD2 1 +ATOM 7093 N N . SER D 1 183 ? 25.218 -53.408 68.321 1.00 65.71 ? 183 SER D N 1 +ATOM 7094 C CA . SER D 1 183 ? 24.766 -54.215 67.216 1.00 81.18 ? 183 SER D CA 1 +ATOM 7095 C C . SER D 1 183 ? 24.928 -55.678 67.570 1.00 121.07 ? 183 SER D C 1 +ATOM 7096 O O . SER D 1 183 ? 25.922 -56.077 68.177 1.00 140.55 ? 183 SER D O 1 +ATOM 7097 C CB . SER D 1 183 ? 25.557 -53.908 65.935 1.00 106.29 ? 183 SER D CB 1 +ATOM 7098 O OG . SER D 1 183 ? 25.836 -52.513 65.813 1.00 183.22 ? 183 SER D OG 1 +ATOM 7099 N N . TYR D 1 184 ? 23.951 -56.494 67.184 1.00 183.94 ? 184 TYR D N 1 +ATOM 7100 C CA . TYR D 1 184 ? 24.042 -57.939 67.399 1.00 166.80 ? 184 TYR D CA 1 +ATOM 7101 C C . TYR D 1 184 ? 23.289 -58.769 66.361 1.00 164.39 ? 184 TYR D C 1 +ATOM 7102 O O . TYR D 1 184 ? 22.302 -58.324 65.765 1.00 143.19 ? 184 TYR D O 1 +ATOM 7103 C CB . TYR D 1 184 ? 23.603 -58.303 68.820 1.00 154.75 ? 184 TYR D CB 1 +ATOM 7104 C CG . TYR D 1 184 ? 22.189 -57.874 69.147 1.00 142.06 ? 184 TYR D CG 1 +ATOM 7105 C CD1 . TYR D 1 184 ? 21.105 -58.675 68.819 1.00 131.89 ? 184 TYR D CD1 1 +ATOM 7106 C CD2 . TYR D 1 184 ? 21.944 -56.668 69.800 1.00 135.06 ? 184 TYR D CD2 1 +ATOM 7107 C CE1 . TYR D 1 184 ? 19.819 -58.289 69.142 1.00 141.03 ? 184 TYR D CE1 1 +ATOM 7108 C CE2 . TYR D 1 184 ? 20.659 -56.269 70.120 1.00 115.28 ? 184 TYR D CE2 1 +ATOM 7109 C CZ . TYR D 1 184 ? 19.603 -57.074 69.786 1.00 124.05 ? 184 TYR D CZ 1 +ATOM 7110 O OH . TYR D 1 184 ? 18.333 -56.714 70.151 1.00 107.44 ? 184 TYR D OH 1 +ATOM 7111 N N . GLU D 1 185 ? 23.763 -60.001 66.199 1.00 201.18 ? 185 GLU D N 1 +ATOM 7112 C CA . GLU D 1 185 ? 23.227 -60.951 65.233 1.00 213.34 ? 185 GLU D CA 1 +ATOM 7113 C C . GLU D 1 185 ? 23.012 -62.323 65.865 1.00 221.76 ? 185 GLU D C 1 +ATOM 7114 O O . GLU D 1 185 ? 23.965 -63.008 66.216 1.00 231.12 ? 185 GLU D O 1 +ATOM 7115 C CB . GLU D 1 185 ? 24.147 -61.116 64.022 1.00 180.81 ? 185 GLU D CB 1 +ATOM 7116 C CG . GLU D 1 185 ? 24.770 -59.843 63.486 1.00 159.43 ? 185 GLU D CG 1 +ATOM 7117 C CD . GLU D 1 185 ? 25.497 -60.093 62.182 1.00 180.06 ? 185 GLU D CD 1 +ATOM 7118 O OE1 . GLU D 1 185 ? 25.527 -61.265 61.722 1.00 217.78 ? 185 GLU D OE1 1 +ATOM 7119 O OE2 . GLU D 1 185 ? 25.983 -59.118 61.583 1.00 157.85 ? 185 GLU D OE2 1 +ATOM 7120 N N . VAL D 1 186 ? 21.750 -62.705 66.004 1.00 191.74 ? 186 VAL D N 1 +ATOM 7121 C CA . VAL D 1 186 ? 21.379 -64.000 66.532 1.00 176.11 ? 186 VAL D CA 1 +ATOM 7122 C C . VAL D 1 186 ? 20.976 -64.921 65.390 1.00 157.58 ? 186 VAL D C 1 +ATOM 7123 O O . VAL D 1 186 ? 20.298 -64.513 64.448 1.00 161.07 ? 186 VAL D O 1 +ATOM 7124 C CB . VAL D 1 186 ? 20.214 -63.876 67.530 1.00 175.95 ? 186 VAL D CB 1 +ATOM 7125 C CG1 . VAL D 1 186 ? 19.969 -65.209 68.223 1.00 200.27 ? 186 VAL D CG1 1 +ATOM 7126 C CG2 . VAL D 1 186 ? 20.502 -62.790 68.553 1.00 158.69 ? 186 VAL D CG2 1 +ATOM 7127 N N . GLN D 1 187 ? 21.384 -66.176 65.474 1.00 152.99 ? 187 GLN D N 1 +ATOM 7128 C CA . GLN D 1 187 ? 21.148 -67.080 64.381 1.00 160.54 ? 187 GLN D CA 1 +ATOM 7129 C C . GLN D 1 187 ? 21.082 -68.557 64.842 1.00 200.05 ? 187 GLN D C 1 +ATOM 7130 O O . GLN D 1 187 ? 21.804 -68.983 65.761 1.00 266.98 ? 187 GLN D O 1 +ATOM 7131 C CB . GLN D 1 187 ? 22.201 -66.813 63.323 1.00 158.05 ? 187 GLN D CB 1 +ATOM 7132 C CG . GLN D 1 187 ? 22.125 -67.751 62.159 1.00 155.85 ? 187 GLN D CG 1 +ATOM 7133 C CD . GLN D 1 187 ? 23.232 -67.502 61.168 1.00 163.23 ? 187 GLN D CD 1 +ATOM 7134 O OE1 . GLN D 1 187 ? 24.327 -67.096 61.543 1.00 160.87 ? 187 GLN D OE1 1 +ATOM 7135 N NE2 . GLN D 1 187 ? 22.933 -67.678 59.887 1.00 189.98 ? 187 GLN D NE2 1 +ATOM 7136 N N . ALA D 1 188 ? 20.123 -69.303 64.294 1.00 200.42 ? 188 ALA D N 1 +ATOM 7137 C CA . ALA D 1 188 ? 19.950 -70.716 64.651 1.00 186.88 ? 188 ALA D CA 1 +ATOM 7138 C C . ALA D 1 188 ? 19.598 -71.534 63.415 1.00 189.45 ? 188 ALA D C 1 +ATOM 7139 O O . ALA D 1 188 ? 18.836 -71.083 62.567 1.00 213.80 ? 188 ALA D O 1 +ATOM 7140 C CB . ALA D 1 188 ? 18.879 -70.880 65.725 1.00 164.16 ? 188 ALA D CB 1 +ATOM 7141 N N . GLY D 1 189 ? 20.168 -72.728 63.308 1.00 191.03 ? 189 GLY D N 1 +ATOM 7142 C CA . GLY D 1 189 ? 19.921 -73.589 62.155 1.00 190.66 ? 189 GLY D CA 1 +ATOM 7143 C C . GLY D 1 189 ? 19.915 -75.064 62.509 1.00 225.14 ? 189 GLY D C 1 +ATOM 7144 O O . GLY D 1 189 ? 20.723 -75.521 63.321 1.00 287.80 ? 189 GLY D O 1 +ATOM 7145 N N . VAL D 1 190 ? 18.987 -75.809 61.916 1.00 225.76 ? 190 VAL D N 1 +ATOM 7146 C CA . VAL D 1 190 ? 18.924 -77.260 62.098 1.00 193.06 ? 190 VAL D CA 1 +ATOM 7147 C C . VAL D 1 190 ? 19.258 -77.950 60.768 1.00 192.26 ? 190 VAL D C 1 +ATOM 7148 O O . VAL D 1 190 ? 18.744 -77.562 59.709 1.00 184.64 ? 190 VAL D O 1 +ATOM 7149 C CB . VAL D 1 190 ? 17.531 -77.700 62.604 1.00 163.05 ? 190 VAL D CB 1 +ATOM 7150 C CG1 . VAL D 1 190 ? 17.559 -79.156 63.034 1.00 143.20 ? 190 VAL D CG1 1 +ATOM 7151 C CG2 . VAL D 1 190 ? 17.057 -76.795 63.743 1.00 137.74 ? 190 VAL D CG2 1 +ATOM 7152 N N . PHE D 1 191 ? 20.118 -78.968 60.821 1.00 199.20 ? 191 PHE D N 1 +ATOM 7153 C CA . PHE D 1 191 ? 20.628 -79.581 59.581 1.00 203.98 ? 191 PHE D CA 1 +ATOM 7154 C C . PHE D 1 191 ? 20.672 -81.124 59.650 1.00 214.35 ? 191 PHE D C 1 +ATOM 7155 O O . PHE D 1 191 ? 20.909 -81.732 60.703 1.00 203.15 ? 191 PHE D O 1 +ATOM 7156 C CB . PHE D 1 191 ? 21.987 -79.040 59.155 1.00 183.77 ? 191 PHE D CB 1 +ATOM 7157 C CG . PHE D 1 191 ? 22.256 -77.604 59.530 1.00 199.76 ? 191 PHE D CG 1 +ATOM 7158 C CD1 . PHE D 1 191 ? 21.786 -76.557 58.760 1.00 197.34 ? 191 PHE D CD1 1 +ATOM 7159 C CD2 . PHE D 1 191 ? 23.028 -77.306 60.642 1.00 216.02 ? 191 PHE D CD2 1 +ATOM 7160 C CE1 . PHE D 1 191 ? 22.046 -75.240 59.113 1.00 196.19 ? 191 PHE D CE1 1 +ATOM 7161 C CE2 . PHE D 1 191 ? 23.283 -75.992 61.007 1.00 208.84 ? 191 PHE D CE2 1 +ATOM 7162 C CZ . PHE D 1 191 ? 22.780 -74.957 60.247 1.00 199.73 ? 191 PHE D CZ 1 +ATOM 7163 N N . ARG D 1 192 ? 20.380 -81.744 58.514 1.00 222.58 ? 192 ARG D N 1 +ATOM 7164 C CA . ARG D 1 192 ? 20.688 -83.144 58.270 1.00 211.37 ? 192 ARG D CA 1 +ATOM 7165 C C . ARG D 1 192 ? 20.848 -83.403 56.759 1.00 229.81 ? 192 ARG D C 1 +ATOM 7166 O O . ARG D 1 192 ? 19.899 -83.770 56.042 1.00 247.04 ? 192 ARG D O 1 +ATOM 7167 C CB . ARG D 1 192 ? 19.636 -84.067 58.871 1.00 197.97 ? 192 ARG D CB 1 +ATOM 7168 C CG . ARG D 1 192 ? 20.136 -85.501 58.990 1.00 174.26 ? 192 ARG D CG 1 +ATOM 7169 C CD . ARG D 1 192 ? 19.221 -86.356 59.856 1.00 174.42 ? 192 ARG D CD 1 +ATOM 7170 N NE . ARG D 1 192 ? 17.815 -86.360 59.441 1.00 163.82 ? 192 ARG D NE 1 +ATOM 7171 C CZ . ARG D 1 192 ? 17.349 -87.119 58.461 1.00 168.13 ? 192 ARG D CZ 1 +ATOM 7172 N NH1 . ARG D 1 192 ? 18.185 -87.891 57.787 1.00 190.12 ? 192 ARG D NH1 1 +ATOM 7173 N NH2 . ARG D 1 192 ? 16.063 -87.085 58.135 1.00 154.07 ? 192 ARG D NH2 1 +ATOM 7174 N N . LEU D 1 200 ? 17.213 -82.464 55.237 1.00 105.90 ? 200 LEU D N 1 +ATOM 7175 C CA . LEU D 1 200 ? 16.536 -81.459 56.057 1.00 133.81 ? 200 LEU D CA 1 +ATOM 7176 C C . LEU D 1 200 ? 17.488 -80.349 56.475 1.00 175.73 ? 200 LEU D C 1 +ATOM 7177 O O . LEU D 1 200 ? 18.412 -80.573 57.274 1.00 209.12 ? 200 LEU D O 1 +ATOM 7178 C CB . LEU D 1 200 ? 15.927 -82.075 57.327 1.00 120.37 ? 200 LEU D CB 1 +ATOM 7179 C CG . LEU D 1 200 ? 15.375 -81.044 58.333 1.00 115.06 ? 200 LEU D CG 1 +ATOM 7180 C CD1 . LEU D 1 200 ? 13.858 -80.947 58.207 1.00 118.31 ? 200 LEU D CD1 1 +ATOM 7181 C CD2 . LEU D 1 200 ? 15.798 -81.321 59.775 1.00 96.82 ? 200 LEU D CD2 1 +ATOM 7182 N N . GLU D 1 201 ? 17.225 -79.143 55.976 1.00 197.43 ? 201 GLU D N 1 +ATOM 7183 C CA . GLU D 1 201 ? 17.793 -77.930 56.561 1.00 192.46 ? 201 GLU D CA 1 +ATOM 7184 C C . GLU D 1 201 ? 16.684 -76.974 56.998 1.00 169.96 ? 201 GLU D C 1 +ATOM 7185 O O . GLU D 1 201 ? 15.627 -76.931 56.382 1.00 118.65 ? 201 GLU D O 1 +ATOM 7186 C CB . GLU D 1 201 ? 18.714 -77.235 55.558 1.00 188.48 ? 201 GLU D CB 1 +ATOM 7187 C CG . GLU D 1 201 ? 19.685 -76.268 56.209 1.00 186.37 ? 201 GLU D CG 1 +ATOM 7188 C CD . GLU D 1 201 ? 20.598 -75.573 55.207 1.00 191.15 ? 201 GLU D CD 1 +ATOM 7189 O OE1 . GLU D 1 201 ? 21.233 -76.264 54.386 1.00 182.88 ? 201 GLU D OE1 1 +ATOM 7190 O OE2 . GLU D 1 201 ? 20.730 -74.334 55.287 1.00 186.62 ? 201 GLU D OE2 1 +ATOM 7191 N N . GLY D 1 202 ? 16.942 -76.202 58.053 1.00 164.50 ? 202 GLY D N 1 +ATOM 7192 C CA . GLY D 1 202 ? 16.048 -75.122 58.474 1.00 172.39 ? 202 GLY D CA 1 +ATOM 7193 C C . GLY D 1 202 ? 16.785 -74.043 59.256 1.00 177.24 ? 202 GLY D C 1 +ATOM 7194 O O . GLY D 1 202 ? 17.494 -74.347 60.214 1.00 206.84 ? 202 GLY D O 1 +ATOM 7195 N N . GLU D 1 203 ? 16.641 -72.784 58.843 1.00 161.29 ? 203 GLU D N 1 +ATOM 7196 C CA . GLU D 1 203 ? 17.392 -71.685 59.454 1.00 155.50 ? 203 GLU D CA 1 +ATOM 7197 C C . GLU D 1 203 ? 16.537 -70.480 59.840 1.00 137.33 ? 203 GLU D C 1 +ATOM 7198 O O . GLU D 1 203 ? 15.673 -70.044 59.079 1.00 178.33 ? 203 GLU D O 1 +ATOM 7199 C CB . GLU D 1 203 ? 18.504 -71.228 58.513 1.00 167.14 ? 203 GLU D CB 1 +ATOM 7200 C CG . GLU D 1 203 ? 19.598 -72.278 58.313 1.00 194.25 ? 203 GLU D CG 1 +ATOM 7201 C CD . GLU D 1 203 ? 20.767 -71.802 57.456 1.00 214.99 ? 203 GLU D CD 1 +ATOM 7202 O OE1 . GLU D 1 203 ? 20.681 -70.694 56.880 1.00 242.18 ? 203 GLU D OE1 1 +ATOM 7203 O OE2 . GLU D 1 203 ? 21.768 -72.549 57.336 1.00 217.07 ? 203 GLU D OE2 1 +ATOM 7204 N N . VAL D 1 204 ? 16.811 -69.938 61.023 1.00 127.53 ? 204 VAL D N 1 +ATOM 7205 C CA . VAL D 1 204 ? 16.246 -68.668 61.485 1.00 151.78 ? 204 VAL D CA 1 +ATOM 7206 C C . VAL D 1 204 ? 17.391 -67.708 61.832 1.00 170.09 ? 204 VAL D C 1 +ATOM 7207 O O . VAL D 1 204 ? 18.366 -68.102 62.473 1.00 160.23 ? 204 VAL D O 1 +ATOM 7208 C CB . VAL D 1 204 ? 15.310 -68.875 62.712 1.00 125.01 ? 204 VAL D CB 1 +ATOM 7209 C CG1 . VAL D 1 204 ? 15.011 -67.566 63.438 1.00 109.94 ? 204 VAL D CG1 1 +ATOM 7210 C CG2 . VAL D 1 204 ? 14.016 -69.537 62.267 1.00 116.26 ? 204 VAL D CG2 1 +ATOM 7211 N N . GLY D 1 205 ? 17.254 -66.449 61.417 1.00 173.53 ? 205 GLY D N 1 +ATOM 7212 C CA . GLY D 1 205 ? 18.214 -65.405 61.769 1.00 153.04 ? 205 GLY D CA 1 +ATOM 7213 C C . GLY D 1 205 ? 17.549 -64.091 62.172 1.00 128.64 ? 205 GLY D C 1 +ATOM 7214 O O . GLY D 1 205 ? 16.450 -63.778 61.719 1.00 134.64 ? 205 GLY D O 1 +ATOM 7215 N N . TYR D 1 206 ? 18.233 -63.307 63.001 1.00 112.47 ? 206 TYR D N 1 +ATOM 7216 C CA . TYR D 1 206 ? 17.802 -61.951 63.353 1.00 104.70 ? 206 TYR D CA 1 +ATOM 7217 C C . TYR D 1 206 ? 19.011 -61.057 63.610 1.00 121.66 ? 206 TYR D C 1 +ATOM 7218 O O . TYR D 1 206 ? 19.985 -61.496 64.209 1.00 157.11 ? 206 TYR D O 1 +ATOM 7219 C CB . TYR D 1 206 ? 16.924 -61.973 64.607 1.00 84.20 ? 206 TYR D CB 1 +ATOM 7220 C CG . TYR D 1 206 ? 16.493 -60.590 65.089 1.00 79.31 ? 206 TYR D CG 1 +ATOM 7221 C CD1 . TYR D 1 206 ? 15.467 -59.891 64.450 1.00 81.05 ? 206 TYR D CD1 1 +ATOM 7222 C CD2 . TYR D 1 206 ? 17.081 -60.003 66.201 1.00 80.55 ? 206 TYR D CD2 1 +ATOM 7223 C CE1 . TYR D 1 206 ? 15.046 -58.647 64.903 1.00 83.84 ? 206 TYR D CE1 1 +ATOM 7224 C CE2 . TYR D 1 206 ? 16.664 -58.759 66.667 1.00 91.82 ? 206 TYR D CE2 1 +ATOM 7225 C CZ . TYR D 1 206 ? 15.651 -58.075 66.010 1.00 91.97 ? 206 TYR D CZ 1 +ATOM 7226 O OH . TYR D 1 206 ? 15.258 -56.823 66.469 1.00 77.91 ? 206 TYR D OH 1 +ATOM 7227 N N . THR D 1 207 ? 18.940 -59.792 63.194 1.00 121.46 ? 207 THR D N 1 +ATOM 7228 C CA . THR D 1 207 ? 20.026 -58.824 63.458 1.00 101.04 ? 207 THR D CA 1 +ATOM 7229 C C . THR D 1 207 ? 19.462 -57.472 63.900 1.00 83.59 ? 207 THR D C 1 +ATOM 7230 O O . THR D 1 207 ? 18.472 -56.985 63.331 1.00 90.17 ? 207 THR D O 1 +ATOM 7231 C CB . THR D 1 207 ? 20.919 -58.622 62.215 1.00 88.84 ? 207 THR D CB 1 +ATOM 7232 O OG1 . THR D 1 207 ? 20.137 -58.091 61.149 1.00 100.29 ? 207 THR D OG1 1 +ATOM 7233 C CG2 . THR D 1 207 ? 21.513 -59.929 61.766 1.00 96.72 ? 207 THR D CG2 1 +ATOM 7234 N N . SER D 1 208 ? 20.068 -56.870 64.921 1.00 81.03 ? 208 SER D N 1 +ATOM 7235 C CA . SER D 1 208 ? 19.635 -55.536 65.385 1.00 120.90 ? 208 SER D CA 1 +ATOM 7236 C C . SER D 1 208 ? 20.789 -54.549 65.548 1.00 139.15 ? 208 SER D C 1 +ATOM 7237 O O . SER D 1 208 ? 21.762 -54.847 66.229 1.00 147.36 ? 208 SER D O 1 +ATOM 7238 C CB . SER D 1 208 ? 18.861 -55.621 66.700 1.00 108.12 ? 208 SER D CB 1 +ATOM 7239 O OG . SER D 1 208 ? 18.581 -54.312 67.204 1.00 76.37 ? 208 SER D OG 1 +ATOM 7240 N N . ASN D 1 209 ? 20.661 -53.392 64.887 1.00 124.57 ? 209 ASN D N 1 +ATOM 7241 C CA . ASN D 1 209 ? 21.587 -52.287 65.026 1.00 83.15 ? 209 ASN D CA 1 +ATOM 7242 C C . ASN D 1 209 ? 20.896 -51.141 65.721 1.00 89.58 ? 209 ASN D C 1 +ATOM 7243 O O . ASN D 1 209 ? 19.774 -50.763 65.365 1.00 96.95 ? 209 ASN D O 1 +ATOM 7244 C CB . ASN D 1 209 ? 22.063 -51.802 63.661 1.00 70.19 ? 209 ASN D CB 1 +ATOM 7245 C CG . ASN D 1 209 ? 22.959 -52.780 62.986 1.00 71.75 ? 209 ASN D CG 1 +ATOM 7246 O OD1 . ASN D 1 209 ? 24.168 -52.861 63.289 1.00 125.33 ? 209 ASN D OD1 1 +ATOM 7247 N ND2 . ASN D 1 209 ? 22.398 -53.547 62.071 1.00 63.23 ? 209 ASN D ND2 1 +ATOM 7248 N N . GLU D 1 210 ? 21.591 -50.524 66.661 1.00 94.51 ? 210 GLU D N 1 +ATOM 7249 C CA . GLU D 1 210 ? 21.166 -49.218 67.150 1.00 125.64 ? 210 GLU D CA 1 +ATOM 7250 C C . GLU D 1 210 ? 21.298 -48.179 66.011 1.00 128.24 ? 210 GLU D C 1 +ATOM 7251 O O . GLU D 1 210 ? 22.262 -48.209 65.244 1.00 147.12 ? 210 GLU D O 1 +ATOM 7252 C CB . GLU D 1 210 ? 22.015 -48.805 68.360 1.00 135.01 ? 210 GLU D CB 1 +ATOM 7253 C CG . GLU D 1 210 ? 21.233 -48.236 69.530 1.00 115.97 ? 210 GLU D CG 1 +ATOM 7254 C CD . GLU D 1 210 ? 22.045 -48.244 70.819 1.00 114.26 ? 210 GLU D CD 1 +ATOM 7255 O OE1 . GLU D 1 210 ? 22.974 -49.078 70.990 1.00 73.15 ? 210 GLU D OE1 1 +ATOM 7256 O OE2 . GLU D 1 210 ? 21.742 -47.385 71.674 1.00 140.08 ? 210 GLU D OE2 1 +ATOM 7257 N N . PRO D 1 211 ? 20.329 -47.262 65.893 1.00 98.40 ? 211 PRO D N 1 +ATOM 7258 C CA . PRO D 1 211 ? 20.527 -46.133 65.003 1.00 111.97 ? 211 PRO D CA 1 +ATOM 7259 C C . PRO D 1 211 ? 21.613 -45.160 65.524 1.00 130.11 ? 211 PRO D C 1 +ATOM 7260 O O . PRO D 1 211 ? 21.510 -44.643 66.648 1.00 124.37 ? 211 PRO D O 1 +ATOM 7261 C CB . PRO D 1 211 ? 19.136 -45.466 64.958 1.00 79.79 ? 211 PRO D CB 1 +ATOM 7262 C CG . PRO D 1 211 ? 18.214 -46.485 65.477 1.00 76.77 ? 211 PRO D CG 1 +ATOM 7263 C CD . PRO D 1 211 ? 19.003 -47.233 66.508 1.00 81.28 ? 211 PRO D CD 1 +ATOM 7264 N N . VAL D 1 212 ? 22.627 -44.908 64.697 1.00 111.29 ? 212 VAL D N 1 +ATOM 7265 C CA . VAL D 1 212 ? 23.662 -43.941 65.021 1.00 98.09 ? 212 VAL D CA 1 +ATOM 7266 C C . VAL D 1 212 ? 23.038 -42.558 65.182 1.00 88.76 ? 212 VAL D C 1 +ATOM 7267 O O . VAL D 1 212 ? 23.396 -41.774 66.078 1.00 129.80 ? 212 VAL D O 1 +ATOM 7268 C CB . VAL D 1 212 ? 24.729 -43.878 63.905 1.00 110.30 ? 212 VAL D CB 1 +ATOM 7269 C CG1 . VAL D 1 212 ? 25.893 -42.973 64.334 1.00 118.96 ? 212 VAL D CG1 1 +ATOM 7270 C CG2 . VAL D 1 212 ? 25.236 -45.275 63.545 1.00 97.76 ? 212 VAL D CG2 1 +ATOM 7271 N N . MET D 1 213 ? 22.159 -42.238 64.244 1.00 77.49 ? 213 MET D N 1 +ATOM 7272 C CA . MET D 1 213 ? 21.211 -41.138 64.348 1.00 95.65 ? 213 MET D CA 1 +ATOM 7273 C C . MET D 1 213 ? 20.716 -40.855 65.789 1.00 95.38 ? 213 MET D C 1 +ATOM 7274 O O . MET D 1 213 ? 20.747 -39.716 66.294 1.00 77.73 ? 213 MET D O 1 +ATOM 7275 C CB . MET D 1 213 ? 20.046 -41.551 63.445 1.00 104.46 ? 213 MET D CB 1 +ATOM 7276 C CG . MET D 1 213 ? 18.931 -40.564 63.245 1.00 135.18 ? 213 MET D CG 1 +ATOM 7277 S SD . MET D 1 213 ? 17.743 -41.308 62.128 1.00 155.54 ? 213 MET D SD 1 +ATOM 7278 C CE . MET D 1 213 ? 16.442 -41.599 63.318 1.00 189.01 ? 213 MET D CE 1 +ATOM 7279 N N . LEU D 1 214 ? 20.257 -41.912 66.441 1.00 99.96 ? 214 LEU D N 1 +ATOM 7280 C CA . LEU D 1 214 ? 19.495 -41.790 67.670 1.00 108.61 ? 214 LEU D CA 1 +ATOM 7281 C C . LEU D 1 214 ? 20.468 -41.648 68.828 1.00 101.23 ? 214 LEU D C 1 +ATOM 7282 O O . LEU D 1 214 ? 20.151 -41.065 69.867 1.00 117.89 ? 214 LEU D O 1 +ATOM 7283 C CB . LEU D 1 214 ? 18.590 -43.023 67.837 1.00 128.75 ? 214 LEU D CB 1 +ATOM 7284 C CG . LEU D 1 214 ? 17.153 -42.831 68.333 1.00 148.27 ? 214 LEU D CG 1 +ATOM 7285 C CD1 . LEU D 1 214 ? 16.338 -41.932 67.413 1.00 146.73 ? 214 LEU D CD1 1 +ATOM 7286 C CD2 . LEU D 1 214 ? 16.473 -44.191 68.476 1.00 164.97 ? 214 LEU D CD2 1 +ATOM 7287 N N . CYS D 1 215 ? 21.646 -42.243 68.666 1.00 106.04 ? 215 CYS D N 1 +ATOM 7288 C CA . CYS D 1 215 ? 22.695 -42.177 69.693 1.00 128.94 ? 215 CYS D CA 1 +ATOM 7289 C C . CYS D 1 215 ? 23.283 -40.772 69.741 1.00 132.78 ? 215 CYS D C 1 +ATOM 7290 O O . CYS D 1 215 ? 23.598 -40.223 70.808 1.00 85.36 ? 215 CYS D O 1 +ATOM 7291 C CB . CYS D 1 215 ? 23.807 -43.183 69.375 1.00 123.02 ? 215 CYS D CB 1 +ATOM 7292 S SG . CYS D 1 215 ? 23.283 -44.899 69.483 1.00 157.99 ? 215 CYS D SG 1 +ATOM 7293 N N . LEU D 1 216 ? 23.479 -40.219 68.548 1.00 150.48 ? 216 LEU D N 1 +ATOM 7294 C CA . LEU D 1 216 ? 23.935 -38.853 68.427 1.00 134.08 ? 216 LEU D CA 1 +ATOM 7295 C C . LEU D 1 216 ? 22.958 -37.953 69.172 1.00 115.33 ? 216 LEU D C 1 +ATOM 7296 O O . LEU D 1 216 ? 23.371 -37.105 69.970 1.00 149.87 ? 216 LEU D O 1 +ATOM 7297 C CB . LEU D 1 216 ? 24.045 -38.445 66.948 1.00 147.02 ? 216 LEU D CB 1 +ATOM 7298 C CG . LEU D 1 216 ? 24.474 -36.995 66.691 1.00 132.99 ? 216 LEU D CG 1 +ATOM 7299 C CD1 . LEU D 1 216 ? 25.813 -36.661 67.344 1.00 127.62 ? 216 LEU D CD1 1 +ATOM 7300 C CD2 . LEU D 1 216 ? 24.539 -36.715 65.205 1.00 112.37 ? 216 LEU D CD2 1 +ATOM 7301 N N . MET D 1 217 ? 21.666 -38.147 68.913 1.00 95.21 ? 217 MET D N 1 +ATOM 7302 C CA . MET D 1 217 ? 20.652 -37.281 69.478 1.00 92.06 ? 217 MET D CA 1 +ATOM 7303 C C . MET D 1 217 ? 20.667 -37.390 71.003 1.00 126.66 ? 217 MET D C 1 +ATOM 7304 O O . MET D 1 217 ? 20.695 -36.374 71.709 1.00 138.55 ? 217 MET D O 1 +ATOM 7305 C CB . MET D 1 217 ? 19.274 -37.630 68.920 1.00 86.30 ? 217 MET D CB 1 +ATOM 7306 C CG . MET D 1 217 ? 18.441 -36.403 68.574 1.00 86.74 ? 217 MET D CG 1 +ATOM 7307 S SD . MET D 1 217 ? 17.917 -35.474 70.045 1.00 144.42 ? 217 MET D SD 1 +ATOM 7308 C CE . MET D 1 217 ? 17.220 -33.982 69.329 1.00 117.65 ? 217 MET D CE 1 +ATOM 7309 N N . SER D 1 218 ? 20.717 -38.624 71.502 1.00 144.73 ? 218 SER D N 1 +ATOM 7310 C CA . SER D 1 218 ? 20.786 -38.888 72.939 1.00 134.60 ? 218 SER D CA 1 +ATOM 7311 C C . SER D 1 218 ? 21.971 -38.166 73.592 1.00 143.60 ? 218 SER D C 1 +ATOM 7312 O O . SER D 1 218 ? 21.818 -37.471 74.613 1.00 147.74 ? 218 SER D O 1 +ATOM 7313 C CB . SER D 1 218 ? 20.913 -40.390 73.187 1.00 140.81 ? 218 SER D CB 1 +ATOM 7314 O OG . SER D 1 218 ? 20.751 -40.695 74.566 1.00 174.21 ? 218 SER D OG 1 +ATOM 7315 N N . ALA D 1 219 ? 23.154 -38.340 73.009 1.00 125.44 ? 219 ALA D N 1 +ATOM 7316 C CA . ALA D 1 219 ? 24.374 -37.772 73.583 1.00 120.03 ? 219 ALA D CA 1 +ATOM 7317 C C . ALA D 1 219 ? 24.347 -36.221 73.618 1.00 99.62 ? 219 ALA D C 1 +ATOM 7318 O O . ALA D 1 219 ? 24.855 -35.587 74.545 1.00 78.57 ? 219 ALA D O 1 +ATOM 7319 C CB . ALA D 1 219 ? 25.577 -38.280 72.808 1.00 115.92 ? 219 ALA D CB 1 +ATOM 7320 N N . ILE D 1 220 ? 23.718 -35.621 72.616 1.00 99.25 ? 220 ILE D N 1 +ATOM 7321 C CA . ILE D 1 220 ? 23.613 -34.167 72.553 1.00 96.21 ? 220 ILE D CA 1 +ATOM 7322 C C . ILE D 1 220 ? 22.706 -33.670 73.674 1.00 107.24 ? 220 ILE D C 1 +ATOM 7323 O O . ILE D 1 220 ? 22.989 -32.653 74.312 1.00 82.79 ? 220 ILE D O 1 +ATOM 7324 C CB . ILE D 1 220 ? 23.100 -33.689 71.166 1.00 101.16 ? 220 ILE D CB 1 +ATOM 7325 C CG1 . ILE D 1 220 ? 24.189 -33.925 70.108 1.00 94.16 ? 220 ILE D CG1 1 +ATOM 7326 C CG2 . ILE D 1 220 ? 22.695 -32.218 71.208 1.00 84.59 ? 220 ILE D CG2 1 +ATOM 7327 C CD1 . ILE D 1 220 ? 23.688 -33.871 68.687 1.00 109.47 ? 220 ILE D CD1 1 +ATOM 7328 N N . GLU D 1 221 ? 21.603 -34.377 73.906 1.00 138.75 ? 221 GLU D N 1 +ATOM 7329 C CA . GLU D 1 221 ? 20.687 -34.030 75.005 1.00 154.25 ? 221 GLU D CA 1 +ATOM 7330 C C . GLU D 1 221 ? 21.436 -34.037 76.345 1.00 133.55 ? 221 GLU D C 1 +ATOM 7331 O O . GLU D 1 221 ? 21.383 -33.068 77.109 1.00 91.61 ? 221 GLU D O 1 +ATOM 7332 C CB . GLU D 1 221 ? 19.509 -35.016 75.044 1.00 163.99 ? 221 GLU D CB 1 +ATOM 7333 C CG . GLU D 1 221 ? 18.489 -34.805 73.934 1.00 170.96 ? 221 GLU D CG 1 +ATOM 7334 C CD . GLU D 1 221 ? 17.564 -35.998 73.719 1.00 172.71 ? 221 GLU D CD 1 +ATOM 7335 O OE1 . GLU D 1 221 ? 18.015 -37.172 73.837 1.00 118.44 ? 221 GLU D OE1 1 +ATOM 7336 O OE2 . GLU D 1 221 ? 16.386 -35.737 73.383 1.00 150.65 ? 221 GLU D OE2 1 +ATOM 7337 N N . THR D 1 222 ? 22.138 -35.143 76.596 1.00 115.68 ? 222 THR D N 1 +ATOM 7338 C CA . THR D 1 222 ? 22.959 -35.324 77.793 1.00 97.30 ? 222 THR D CA 1 +ATOM 7339 C C . THR D 1 222 ? 23.914 -34.153 77.972 1.00 106.23 ? 222 THR D C 1 +ATOM 7340 O O . THR D 1 222 ? 24.025 -33.601 79.067 1.00 95.15 ? 222 THR D O 1 +ATOM 7341 C CB . THR D 1 222 ? 23.787 -36.619 77.676 1.00 101.05 ? 222 THR D CB 1 +ATOM 7342 O OG1 . THR D 1 222 ? 22.918 -37.762 77.795 1.00 104.60 ? 222 THR D OG1 1 +ATOM 7343 C CG2 . THR D 1 222 ? 24.925 -36.660 78.714 1.00 87.32 ? 222 THR D CG2 1 +ATOM 7344 N N . GLY D 1 223 ? 24.608 -33.795 76.888 1.00 113.43 ? 223 GLY D N 1 +ATOM 7345 C CA . GLY D 1 223 ? 25.503 -32.638 76.879 1.00 99.52 ? 223 GLY D CA 1 +ATOM 7346 C C . GLY D 1 223 ? 24.811 -31.342 77.264 1.00 89.77 ? 223 GLY D C 1 +ATOM 7347 O O . GLY D 1 223 ? 25.362 -30.540 78.036 1.00 96.17 ? 223 GLY D O 1 +ATOM 7348 N N . VAL D 1 224 ? 23.572 -31.164 76.799 1.00 66.37 ? 224 VAL D N 1 +ATOM 7349 C CA . VAL D 1 224 ? 22.818 -29.966 77.130 1.00 82.87 ? 224 VAL D CA 1 +ATOM 7350 C C . VAL D 1 224 ? 22.526 -29.912 78.633 1.00 105.86 ? 224 VAL D C 1 +ATOM 7351 O O . VAL D 1 224 ? 22.662 -28.856 79.269 1.00 92.62 ? 224 VAL D O 1 +ATOM 7352 C CB . VAL D 1 224 ? 21.492 -29.880 76.358 1.00 91.74 ? 224 VAL D CB 1 +ATOM 7353 C CG1 . VAL D 1 224 ? 20.659 -28.703 76.860 1.00 93.07 ? 224 VAL D CG1 1 +ATOM 7354 C CG2 . VAL D 1 224 ? 21.755 -29.744 74.870 1.00 88.28 ? 224 VAL D CG2 1 +ATOM 7355 N N . ILE D 1 225 ? 22.166 -31.054 79.207 1.00 134.24 ? 225 ILE D N 1 +ATOM 7356 C CA . ILE D 1 225 ? 21.918 -31.120 80.645 1.00 139.87 ? 225 ILE D CA 1 +ATOM 7357 C C . ILE D 1 225 ? 23.175 -30.743 81.424 1.00 130.88 ? 225 ILE D C 1 +ATOM 7358 O O . ILE D 1 225 ? 23.112 -29.862 82.285 1.00 101.21 ? 225 ILE D O 1 +ATOM 7359 C CB . ILE D 1 225 ? 21.426 -32.511 81.086 1.00 159.64 ? 225 ILE D CB 1 +ATOM 7360 C CG1 . ILE D 1 225 ? 20.029 -32.780 80.523 1.00 168.80 ? 225 ILE D CG1 1 +ATOM 7361 C CG2 . ILE D 1 225 ? 21.371 -32.595 82.601 1.00 161.03 ? 225 ILE D CG2 1 +ATOM 7362 C CD1 . ILE D 1 225 ? 19.639 -34.242 80.534 1.00 175.41 ? 225 ILE D CD1 1 +ATOM 7363 N N . PHE D 1 226 ? 24.304 -31.401 81.121 1.00 116.61 ? 226 PHE D N 1 +ATOM 7364 C CA . PHE D 1 226 ? 25.577 -31.099 81.785 1.00 116.59 ? 226 PHE D CA 1 +ATOM 7365 C C . PHE D 1 226 ? 25.944 -29.612 81.670 1.00 118.10 ? 226 PHE D C 1 +ATOM 7366 O O . PHE D 1 226 ? 26.542 -29.032 82.577 1.00 115.55 ? 226 PHE D O 1 +ATOM 7367 C CB . PHE D 1 226 ? 26.725 -31.951 81.222 1.00 124.48 ? 226 PHE D CB 1 +ATOM 7368 C CG . PHE D 1 226 ? 26.790 -33.360 81.774 1.00 130.86 ? 226 PHE D CG 1 +ATOM 7369 C CD1 . PHE D 1 226 ? 26.985 -33.589 83.134 1.00 125.05 ? 226 PHE D CD1 1 +ATOM 7370 C CD2 . PHE D 1 226 ? 26.774 -34.453 80.912 1.00 131.75 ? 226 PHE D CD2 1 +ATOM 7371 C CE1 . PHE D 1 226 ? 27.061 -34.876 83.632 1.00 127.09 ? 226 PHE D CE1 1 +ATOM 7372 C CE2 . PHE D 1 226 ? 26.914 -35.740 81.391 1.00 124.97 ? 226 PHE D CE2 1 +ATOM 7373 C CZ . PHE D 1 226 ? 27.014 -35.957 82.760 1.00 154.34 ? 226 PHE D CZ 1 +ATOM 7374 N N . LEU D 1 227 ? 25.596 -29.001 80.547 1.00 127.65 ? 227 LEU D N 1 +ATOM 7375 C CA . LEU D 1 227 ? 25.827 -27.579 80.348 1.00 130.59 ? 227 LEU D CA 1 +ATOM 7376 C C . LEU D 1 227 ? 24.974 -26.742 81.283 1.00 107.55 ? 227 LEU D C 1 +ATOM 7377 O O . LEU D 1 227 ? 25.475 -25.777 81.874 1.00 166.33 ? 227 LEU D O 1 +ATOM 7378 C CB . LEU D 1 227 ? 25.544 -27.205 78.891 1.00 135.65 ? 227 LEU D CB 1 +ATOM 7379 C CG . LEU D 1 227 ? 26.630 -27.588 77.866 1.00 116.02 ? 227 LEU D CG 1 +ATOM 7380 C CD1 . LEU D 1 227 ? 26.206 -27.486 76.420 1.00 114.67 ? 227 LEU D CD1 1 +ATOM 7381 C CD2 . LEU D 1 227 ? 27.885 -26.777 78.071 1.00 117.19 ? 227 LEU D CD2 1 +ATOM 7382 N N . ILE D 1 228 ? 23.703 -27.098 81.416 1.00 92.70 ? 228 ILE D N 1 +ATOM 7383 C CA . ILE D 1 228 ? 22.793 -26.329 82.263 1.00 127.80 ? 228 ILE D CA 1 +ATOM 7384 C C . ILE D 1 228 ? 23.238 -26.454 83.718 1.00 143.30 ? 228 ILE D C 1 +ATOM 7385 O O . ILE D 1 228 ? 23.330 -25.456 84.439 1.00 149.31 ? 228 ILE D O 1 +ATOM 7386 C CB . ILE D 1 228 ? 21.322 -26.794 82.146 1.00 119.80 ? 228 ILE D CB 1 +ATOM 7387 C CG1 . ILE D 1 228 ? 20.784 -26.551 80.739 1.00 128.22 ? 228 ILE D CG1 1 +ATOM 7388 C CG2 . ILE D 1 228 ? 20.446 -26.033 83.131 1.00 94.11 ? 228 ILE D CG2 1 +ATOM 7389 C CD1 . ILE D 1 228 ? 19.509 -27.303 80.420 1.00 127.57 ? 228 ILE D CD1 1 +ATOM 7390 N N . ASN D 1 229 ? 23.533 -27.680 84.134 1.00 138.17 ? 229 ASN D N 1 +ATOM 7391 C CA . ASN D 1 229 ? 23.948 -27.950 85.510 1.00 131.10 ? 229 ASN D CA 1 +ATOM 7392 C C . ASN D 1 229 ? 25.245 -27.225 85.836 1.00 115.67 ? 229 ASN D C 1 +ATOM 7393 O O . ASN D 1 229 ? 25.353 -26.575 86.877 1.00 120.79 ? 229 ASN D O 1 +ATOM 7394 C CB . ASN D 1 229 ? 24.126 -29.456 85.713 1.00 144.45 ? 229 ASN D CB 1 +ATOM 7395 C CG . ASN D 1 229 ? 24.168 -29.852 87.171 1.00 148.69 ? 229 ASN D CG 1 +ATOM 7396 O OD1 . ASN D 1 229 ? 23.658 -29.142 88.042 1.00 150.98 ? 229 ASN D OD1 1 +ATOM 7397 N ND2 . ASN D 1 229 ? 24.768 -31.000 87.445 1.00 162.26 ? 229 ASN D ND2 1 +ATOM 7398 N N . ASP D 1 230 ? 26.195 -27.286 84.906 1.00 103.17 ? 230 ASP D N 1 +ATOM 7399 C CA . ASP D 1 230 ? 27.452 -26.557 85.031 1.00 103.57 ? 230 ASP D CA 1 +ATOM 7400 C C . ASP D 1 230 ? 27.222 -25.041 85.159 1.00 112.31 ? 230 ASP D C 1 +ATOM 7401 O O . ASP D 1 230 ? 27.849 -24.367 85.979 1.00 102.89 ? 230 ASP D O 1 +ATOM 7402 C CB . ASP D 1 230 ? 28.352 -26.834 83.825 1.00 103.27 ? 230 ASP D CB 1 +ATOM 7403 C CG . ASP D 1 230 ? 29.737 -26.236 83.980 1.00 122.63 ? 230 ASP D CG 1 +ATOM 7404 O OD1 . ASP D 1 230 ? 30.514 -26.772 84.796 1.00 185.86 ? 230 ASP D OD1 1 +ATOM 7405 O OD2 . ASP D 1 230 ? 30.054 -25.225 83.321 1.00 122.64 ? 230 ASP D OD2 1 +ATOM 7406 N N . GLY D 1 231 ? 26.294 -24.511 84.368 1.00 138.86 ? 231 GLY D N 1 +ATOM 7407 C CA . GLY D 1 231 ? 25.980 -23.081 84.402 1.00 154.00 ? 231 GLY D CA 1 +ATOM 7408 C C . GLY D 1 231 ? 25.293 -22.665 85.693 1.00 154.34 ? 231 GLY D C 1 +ATOM 7409 O O . GLY D 1 231 ? 25.539 -21.562 86.211 1.00 177.86 ? 231 GLY D O 1 +ATOM 7410 N N . ILE D 1 232 ? 24.478 -23.568 86.243 1.00 145.15 ? 232 ILE D N 1 +ATOM 7411 C CA . ILE D 1 232 ? 23.858 -23.352 87.557 1.00 155.71 ? 232 ILE D CA 1 +ATOM 7412 C C . ILE D 1 232 ? 24.917 -23.225 88.653 1.00 173.26 ? 232 ILE D C 1 +ATOM 7413 O O . ILE D 1 232 ? 24.916 -22.251 89.406 1.00 142.34 ? 232 ILE D O 1 +ATOM 7414 C CB . ILE D 1 232 ? 22.889 -24.495 87.925 1.00 152.92 ? 232 ILE D CB 1 +ATOM 7415 C CG1 . ILE D 1 232 ? 21.625 -24.389 87.067 1.00 166.29 ? 232 ILE D CG1 1 +ATOM 7416 C CG2 . ILE D 1 232 ? 22.540 -24.463 89.416 1.00 134.44 ? 232 ILE D CG2 1 +ATOM 7417 C CD1 . ILE D 1 232 ? 20.802 -25.656 87.029 1.00 169.57 ? 232 ILE D CD1 1 +ATOM 7418 N N . ASP D 1 233 ? 25.843 -24.186 88.692 1.00 211.55 ? 233 ASP D N 1 +ATOM 7419 C CA . ASP D 1 233 ? 26.981 -24.154 89.624 1.00 195.84 ? 233 ASP D CA 1 +ATOM 7420 C C . ASP D 1 233 ? 27.795 -22.859 89.501 1.00 203.91 ? 233 ASP D C 1 +ATOM 7421 O O . ASP D 1 233 ? 28.066 -22.197 90.497 1.00 229.13 ? 233 ASP D O 1 +ATOM 7422 C CB . ASP D 1 233 ? 27.916 -25.354 89.391 1.00 168.28 ? 233 ASP D CB 1 +ATOM 7423 C CG . ASP D 1 233 ? 27.250 -26.694 89.687 1.00 142.88 ? 233 ASP D CG 1 +ATOM 7424 O OD1 . ASP D 1 233 ? 26.016 -26.726 89.899 1.00 129.04 ? 233 ASP D OD1 1 +ATOM 7425 O OD2 . ASP D 1 233 ? 27.968 -27.717 89.704 1.00 131.67 ? 233 ASP D OD2 1 +ATOM 7426 N N . ARG D 1 234 ? 28.155 -22.489 88.275 1.00 216.08 ? 234 ARG D N 1 +ATOM 7427 C CA . ARG D 1 234 ? 29.046 -21.348 88.041 1.00 191.08 ? 234 ARG D CA 1 +ATOM 7428 C C . ARG D 1 234 ? 28.352 -19.980 88.074 1.00 165.65 ? 234 ARG D C 1 +ATOM 7429 O O . ARG D 1 234 ? 29.003 -18.948 87.901 1.00 174.91 ? 234 ARG D O 1 +ATOM 7430 C CB . ARG D 1 234 ? 29.778 -21.535 86.714 1.00 192.58 ? 234 ARG D CB 1 +ATOM 7431 C CG . ARG D 1 234 ? 30.836 -22.611 86.806 1.00 156.33 ? 234 ARG D CG 1 +ATOM 7432 C CD . ARG D 1 234 ? 31.209 -23.181 85.458 1.00 146.78 ? 234 ARG D CD 1 +ATOM 7433 N NE . ARG D 1 234 ? 32.196 -24.232 85.698 1.00 120.83 ? 234 ARG D NE 1 +ATOM 7434 C CZ . ARG D 1 234 ? 33.438 -24.228 85.231 1.00 90.72 ? 234 ARG D CZ 1 +ATOM 7435 N NH1 . ARG D 1 234 ? 33.802 -23.286 84.382 1.00 93.66 ? 234 ARG D NH1 1 +ATOM 7436 N NH2 . ARG D 1 234 ? 34.272 -25.201 85.551 1.00 69.21 ? 234 ARG D NH2 1 +ATOM 7437 N N . GLY D 1 235 ? 27.038 -19.971 88.286 1.00 131.88 ? 235 GLY D N 1 +ATOM 7438 C CA . GLY D 1 235 ? 26.290 -18.727 88.408 1.00 121.85 ? 235 GLY D CA 1 +ATOM 7439 C C . GLY D 1 235 ? 26.049 -18.022 87.086 1.00 126.96 ? 235 GLY D C 1 +ATOM 7440 O O . GLY D 1 235 ? 26.004 -16.788 87.037 1.00 126.46 ? 235 GLY D O 1 +ATOM 7441 N N . LEU D 1 236 ? 25.914 -18.787 86.002 1.00 128.32 ? 236 LEU D N 1 +ATOM 7442 C CA . LEU D 1 236 ? 25.454 -18.206 84.735 1.00 130.15 ? 236 LEU D CA 1 +ATOM 7443 C C . LEU D 1 236 ? 23.963 -17.901 84.845 1.00 130.22 ? 236 LEU D C 1 +ATOM 7444 O O . LEU D 1 236 ? 23.511 -16.811 84.493 1.00 98.93 ? 236 LEU D O 1 +ATOM 7445 C CB . LEU D 1 236 ? 25.711 -19.149 83.542 1.00 136.11 ? 236 LEU D CB 1 +ATOM 7446 C CG . LEU D 1 236 ? 27.105 -19.134 82.890 1.00 114.86 ? 236 LEU D CG 1 +ATOM 7447 C CD1 . LEU D 1 236 ? 28.093 -19.926 83.724 1.00 90.19 ? 236 LEU D CD1 1 +ATOM 7448 C CD2 . LEU D 1 236 ? 27.033 -19.700 81.475 1.00 120.77 ? 236 LEU D CD2 1 +ATOM 7449 N N . TRP D 1 237 ? 23.201 -18.881 85.322 1.00 156.39 ? 237 TRP D N 1 +ATOM 7450 C CA . TRP D 1 237 ? 21.750 -18.747 85.439 1.00 171.93 ? 237 TRP D CA 1 +ATOM 7451 C C . TRP D 1 237 ? 21.267 -19.365 86.752 1.00 188.57 ? 237 TRP D C 1 +ATOM 7452 O O . TRP D 1 237 ? 22.009 -20.117 87.402 1.00 187.02 ? 237 TRP D O 1 +ATOM 7453 C CB . TRP D 1 237 ? 21.059 -19.391 84.234 1.00 162.56 ? 237 TRP D CB 1 +ATOM 7454 C CG . TRP D 1 237 ? 21.804 -20.580 83.710 1.00 169.13 ? 237 TRP D CG 1 +ATOM 7455 C CD1 . TRP D 1 237 ? 21.987 -21.771 84.347 1.00 183.98 ? 237 TRP D CD1 1 +ATOM 7456 C CD2 . TRP D 1 237 ? 22.480 -20.691 82.452 1.00 139.51 ? 237 TRP D CD2 1 +ATOM 7457 N NE1 . TRP D 1 237 ? 22.733 -22.619 83.566 1.00 174.91 ? 237 TRP D NE1 1 +ATOM 7458 C CE2 . TRP D 1 237 ? 23.043 -21.987 82.392 1.00 139.74 ? 237 TRP D CE2 1 +ATOM 7459 C CE3 . TRP D 1 237 ? 22.636 -19.839 81.363 1.00 124.28 ? 237 TRP D CE3 1 +ATOM 7460 C CZ2 . TRP D 1 237 ? 23.784 -22.437 81.302 1.00 111.37 ? 237 TRP D CZ2 1 +ATOM 7461 C CZ3 . TRP D 1 237 ? 23.359 -20.295 80.275 1.00 141.05 ? 237 TRP D CZ3 1 +ATOM 7462 C CH2 . TRP D 1 237 ? 23.925 -21.586 80.257 1.00 123.29 ? 237 TRP D CH2 1 +ATOM 7463 N N . ASP D 1 238 ? 20.031 -19.043 87.137 1.00 181.56 ? 238 ASP D N 1 +ATOM 7464 C CA . ASP D 1 238 ? 19.500 -19.439 88.445 1.00 190.89 ? 238 ASP D CA 1 +ATOM 7465 C C . ASP D 1 238 ? 18.137 -20.128 88.371 1.00 183.95 ? 238 ASP D C 1 +ATOM 7466 O O . ASP D 1 238 ? 17.314 -19.819 87.500 1.00 147.61 ? 238 ASP D O 1 +ATOM 7467 C CB . ASP D 1 238 ? 19.396 -18.229 89.370 1.00 177.48 ? 238 ASP D CB 1 +ATOM 7468 C CG . ASP D 1 238 ? 20.717 -17.511 89.539 1.00 164.44 ? 238 ASP D CG 1 +ATOM 7469 O OD1 . ASP D 1 238 ? 21.072 -16.732 88.636 1.00 152.97 ? 238 ASP D OD1 1 +ATOM 7470 O OD2 . ASP D 1 238 ? 21.396 -17.714 90.571 1.00 177.16 ? 238 ASP D OD2 1 +ATOM 7471 N N . LEU D 1 239 ? 17.904 -21.046 89.314 1.00 164.95 ? 239 LEU D N 1 +ATOM 7472 C CA . LEU D 1 239 ? 16.663 -21.808 89.372 1.00 154.33 ? 239 LEU D CA 1 +ATOM 7473 C C . LEU D 1 239 ? 15.543 -20.954 89.940 1.00 149.64 ? 239 LEU D C 1 +ATOM 7474 O O . LEU D 1 239 ? 15.767 -20.114 90.814 1.00 160.13 ? 239 LEU D O 1 +ATOM 7475 C CB . LEU D 1 239 ? 16.831 -23.059 90.241 1.00 153.47 ? 239 LEU D CB 1 +ATOM 7476 C CG . LEU D 1 239 ? 17.569 -24.272 89.678 1.00 160.17 ? 239 LEU D CG 1 +ATOM 7477 C CD1 . LEU D 1 239 ? 17.518 -25.433 90.662 1.00 176.44 ? 239 LEU D CD1 1 +ATOM 7478 C CD2 . LEU D 1 239 ? 16.975 -24.697 88.353 1.00 156.78 ? 239 LEU D CD2 1 +ATOM 7479 N N . GLN D 1 240 ? 14.339 -21.159 89.416 1.00 145.35 ? 240 GLN D N 1 +ATOM 7480 C CA . GLN D 1 240 ? 13.137 -20.567 89.998 1.00 130.66 ? 240 GLN D CA 1 +ATOM 7481 C C . GLN D 1 240 ? 13.040 -20.917 91.480 1.00 141.58 ? 240 GLN D C 1 +ATOM 7482 O O . GLN D 1 240 ? 12.971 -20.037 92.338 1.00 135.83 ? 240 GLN D O 1 +ATOM 7483 C CB . GLN D 1 240 ? 11.889 -21.065 89.256 1.00 128.33 ? 240 GLN D CB 1 +ATOM 7484 C CG . GLN D 1 240 ? 10.606 -20.352 89.661 1.00 128.06 ? 240 GLN D CG 1 +ATOM 7485 C CD . GLN D 1 240 ? 10.624 -18.882 89.283 1.00 128.76 ? 240 GLN D CD 1 +ATOM 7486 O OE1 . GLN D 1 240 ? 10.372 -18.525 88.129 1.00 132.85 ? 240 GLN D OE1 1 +ATOM 7487 N NE2 . GLN D 1 240 ? 10.971 -18.024 90.240 1.00 128.02 ? 240 GLN D NE2 1 +ATOM 7488 N N . ASN D 1 241 ? 13.060 -22.215 91.763 1.00 174.06 ? 241 ASN D N 1 +ATOM 7489 C CA . ASN D 1 241 ? 12.994 -22.731 93.127 1.00 179.34 ? 241 ASN D CA 1 +ATOM 7490 C C . ASN D 1 241 ? 14.350 -23.228 93.585 1.00 190.95 ? 241 ASN D C 1 +ATOM 7491 O O . ASN D 1 241 ? 14.837 -24.266 93.109 1.00 223.62 ? 241 ASN D O 1 +ATOM 7492 C CB . ASN D 1 241 ? 12.001 -23.885 93.199 1.00 188.37 ? 241 ASN D CB 1 +ATOM 7493 C CG . ASN D 1 241 ? 10.671 -23.464 93.767 1.00 203.27 ? 241 ASN D CG 1 +ATOM 7494 O OD1 . ASN D 1 241 ? 10.381 -23.738 94.926 1.00 220.49 ? 241 ASN D OD1 1 +ATOM 7495 N ND2 . ASN D 1 241 ? 9.853 -22.792 92.955 1.00 213.43 ? 241 ASN D ND2 1 +ATOM 7496 N N . LYS D 1 242 ? 14.940 -22.510 94.533 1.00 168.11 ? 242 LYS D N 1 +ATOM 7497 C CA . LYS D 1 242 ? 16.251 -22.878 95.048 1.00 184.45 ? 242 LYS D CA 1 +ATOM 7498 C C . LYS D 1 242 ? 16.148 -24.210 95.782 1.00 184.61 ? 242 LYS D C 1 +ATOM 7499 O O . LYS D 1 242 ? 17.130 -24.964 95.871 1.00 177.19 ? 242 LYS D O 1 +ATOM 7500 C CB . LYS D 1 242 ? 16.800 -21.777 95.963 1.00 185.14 ? 242 LYS D CB 1 +ATOM 7501 C CG . LYS D 1 242 ? 16.736 -20.380 95.354 1.00 176.40 ? 242 LYS D CG 1 +ATOM 7502 C CD . LYS D 1 242 ? 18.092 -19.686 95.357 1.00 166.95 ? 242 LYS D CD 1 +ATOM 7503 C CE . LYS D 1 242 ? 18.383 -19.048 94.005 1.00 161.45 ? 242 LYS D CE 1 +ATOM 7504 N NZ . LYS D 1 242 ? 19.623 -18.231 94.016 1.00 159.17 ? 242 LYS D NZ 1 +ATOM 7505 N N . ALA D 1 243 ? 14.937 -24.492 96.269 1.00 182.75 ? 243 ALA D N 1 +ATOM 7506 C CA . ALA D 1 243 ? 14.596 -25.765 96.900 1.00 198.19 ? 243 ALA D CA 1 +ATOM 7507 C C . ALA D 1 243 ? 14.745 -26.927 95.927 1.00 215.93 ? 243 ALA D C 1 +ATOM 7508 O O . ALA D 1 243 ? 14.832 -28.085 96.352 1.00 246.17 ? 243 ALA D O 1 +ATOM 7509 C CB . ALA D 1 243 ? 13.170 -25.722 97.442 1.00 178.65 ? 243 ALA D CB 1 +ATOM 7510 N N . GLU D 1 244 ? 14.749 -26.629 94.626 1.00 205.47 ? 244 GLU D N 1 +ATOM 7511 C CA . GLU D 1 244 ? 14.822 -27.685 93.625 1.00 188.43 ? 244 GLU D CA 1 +ATOM 7512 C C . GLU D 1 244 ? 16.250 -27.981 93.204 1.00 150.94 ? 244 GLU D C 1 +ATOM 7513 O O . GLU D 1 244 ? 16.455 -28.688 92.225 1.00 150.54 ? 244 GLU D O 1 +ATOM 7514 C CB . GLU D 1 244 ? 13.969 -27.338 92.399 1.00 187.92 ? 244 GLU D CB 1 +ATOM 7515 C CG . GLU D 1 244 ? 12.470 -27.451 92.632 1.00 180.59 ? 244 GLU D CG 1 +ATOM 7516 C CD . GLU D 1 244 ? 11.669 -27.362 91.343 1.00 160.95 ? 244 GLU D CD 1 +ATOM 7517 O OE1 . GLU D 1 244 ? 11.496 -26.235 90.822 1.00 119.99 ? 244 GLU D OE1 1 +ATOM 7518 O OE2 . GLU D 1 244 ? 11.188 -28.416 90.871 1.00 146.38 ? 244 GLU D OE2 1 +ATOM 7519 N N . ARG D 1 245 ? 17.228 -27.441 93.928 1.00 139.89 ? 245 ARG D N 1 +ATOM 7520 C CA . ARG D 1 245 ? 18.634 -27.759 93.657 1.00 177.08 ? 245 ARG D CA 1 +ATOM 7521 C C . ARG D 1 245 ? 18.928 -29.252 93.745 1.00 189.69 ? 245 ARG D C 1 +ATOM 7522 O O . ARG D 1 245 ? 19.747 -29.771 92.984 1.00 148.82 ? 245 ARG D O 1 +ATOM 7523 C CB . ARG D 1 245 ? 19.576 -27.027 94.599 1.00 182.56 ? 245 ARG D CB 1 +ATOM 7524 C CG . ARG D 1 245 ? 21.055 -27.197 94.231 1.00 179.84 ? 245 ARG D CG 1 +ATOM 7525 C CD . ARG D 1 245 ? 21.997 -26.373 95.130 1.00 186.03 ? 245 ARG D CD 1 +ATOM 7526 N NE . ARG D 1 245 ? 22.389 -25.110 94.500 1.00 180.16 ? 245 ARG D NE 1 +ATOM 7527 C CZ . ARG D 1 245 ? 23.226 -25.006 93.467 1.00 166.09 ? 245 ARG D CZ 1 +ATOM 7528 N NH1 . ARG D 1 245 ? 23.747 -26.084 92.913 1.00 158.86 ? 245 ARG D NH1 1 +ATOM 7529 N NH2 . ARG D 1 245 ? 23.526 -23.814 92.962 1.00 170.50 ? 245 ARG D NH2 1 +ATOM 7530 N N . GLN D 1 246 ? 18.270 -29.938 94.678 1.00 212.54 ? 246 GLN D N 1 +ATOM 7531 C CA . GLN D 1 246 ? 18.525 -31.364 94.891 1.00 206.17 ? 246 GLN D CA 1 +ATOM 7532 C C . GLN D 1 246 ? 17.566 -32.246 94.093 1.00 188.81 ? 246 GLN D C 1 +ATOM 7533 O O . GLN D 1 246 ? 17.365 -33.411 94.419 1.00 177.63 ? 246 GLN D O 1 +ATOM 7534 C CB . GLN D 1 246 ? 18.454 -31.699 96.383 1.00 185.23 ? 246 GLN D CB 1 +ATOM 7535 C CG . GLN D 1 246 ? 19.539 -30.997 97.195 1.00 163.58 ? 246 GLN D CG 1 +ATOM 7536 C CD . GLN D 1 246 ? 20.938 -31.587 97.033 1.00 178.30 ? 246 GLN D CD 1 +ATOM 7537 O OE1 . GLN D 1 246 ? 21.398 -31.839 95.920 1.00 217.24 ? 246 GLN D OE1 1 +ATOM 7538 N NE2 . GLN D 1 246 ? 21.641 -31.758 98.148 1.00 173.05 ? 246 GLN D NE2 1 +ATOM 7539 N N . ASN D 1 247 ? 16.983 -31.673 93.045 1.00 167.01 ? 247 ASN D N 1 +ATOM 7540 C CA . ASN D 1 247 ? 16.263 -32.432 92.029 1.00 156.50 ? 247 ASN D CA 1 +ATOM 7541 C C . ASN D 1 247 ? 16.973 -33.738 91.668 1.00 162.51 ? 247 ASN D C 1 +ATOM 7542 O O . ASN D 1 247 ? 18.200 -33.758 91.498 1.00 176.33 ? 247 ASN D O 1 +ATOM 7543 C CB . ASN D 1 247 ? 16.128 -31.579 90.766 1.00 176.50 ? 247 ASN D CB 1 +ATOM 7544 C CG . ASN D 1 247 ? 14.933 -31.962 89.938 1.00 166.73 ? 247 ASN D CG 1 +ATOM 7545 O OD1 . ASN D 1 247 ? 15.069 -32.514 88.836 1.00 187.44 ? 247 ASN D OD1 1 +ATOM 7546 N ND2 . ASN D 1 247 ? 13.750 -31.634 90.441 1.00 139.83 ? 247 ASN D ND2 1 +ATOM 7547 N N . ASP D 1 248 ? 16.200 -34.813 91.509 1.00 158.58 ? 248 ASP D N 1 +ATOM 7548 C CA . ASP D 1 248 ? 16.761 -36.146 91.210 1.00 182.33 ? 248 ASP D CA 1 +ATOM 7549 C C . ASP D 1 248 ? 17.701 -36.109 89.999 1.00 201.56 ? 248 ASP D C 1 +ATOM 7550 O O . ASP D 1 248 ? 18.803 -36.683 90.012 1.00 187.30 ? 248 ASP D O 1 +ATOM 7551 C CB . ASP D 1 248 ? 15.640 -37.159 90.918 1.00 179.51 ? 248 ASP D CB 1 +ATOM 7552 C CG . ASP D 1 248 ? 14.847 -37.540 92.150 1.00 178.70 ? 248 ASP D CG 1 +ATOM 7553 O OD1 . ASP D 1 248 ? 15.446 -37.676 93.243 1.00 204.54 ? 248 ASP D OD1 1 +ATOM 7554 O OD2 . ASP D 1 248 ? 13.619 -37.723 92.019 1.00 156.30 ? 248 ASP D OD2 1 +ATOM 7555 N N . ILE D 1 249 ? 17.233 -35.458 88.938 1.00 199.35 ? 249 ILE D N 1 +ATOM 7556 C CA . ILE D 1 249 ? 17.957 -35.406 87.679 1.00 176.86 ? 249 ILE D CA 1 +ATOM 7557 C C . ILE D 1 249 ? 19.250 -34.604 87.860 1.00 161.69 ? 249 ILE D C 1 +ATOM 7558 O O . ILE D 1 249 ? 20.342 -35.061 87.496 1.00 163.93 ? 249 ILE D O 1 +ATOM 7559 C CB . ILE D 1 249 ? 17.080 -34.777 86.577 1.00 168.91 ? 249 ILE D CB 1 +ATOM 7560 C CG1 . ILE D 1 249 ? 15.839 -35.644 86.317 1.00 144.36 ? 249 ILE D CG1 1 +ATOM 7561 C CG2 . ILE D 1 249 ? 17.875 -34.630 85.289 1.00 201.27 ? 249 ILE D CG2 1 +ATOM 7562 C CD1 . ILE D 1 249 ? 14.701 -34.913 85.638 1.00 131.58 ? 249 ILE D CD1 1 +ATOM 7563 N N . LEU D 1 250 ? 19.122 -33.424 88.459 1.00 131.88 ? 250 LEU D N 1 +ATOM 7564 C CA . LEU D 1 250 ? 20.267 -32.533 88.650 1.00 137.00 ? 250 LEU D CA 1 +ATOM 7565 C C . LEU D 1 250 ? 21.370 -33.162 89.496 1.00 161.56 ? 250 LEU D C 1 +ATOM 7566 O O . LEU D 1 250 ? 22.556 -32.957 89.225 1.00 183.91 ? 250 LEU D O 1 +ATOM 7567 C CB . LEU D 1 250 ? 19.819 -31.218 89.286 1.00 136.70 ? 250 LEU D CB 1 +ATOM 7568 C CG . LEU D 1 250 ? 19.194 -30.206 88.321 1.00 140.20 ? 250 LEU D CG 1 +ATOM 7569 C CD1 . LEU D 1 250 ? 18.515 -29.061 89.055 1.00 135.05 ? 250 LEU D CD1 1 +ATOM 7570 C CD2 . LEU D 1 250 ? 20.254 -29.662 87.381 1.00 157.52 ? 250 LEU D CD2 1 +ATOM 7571 N N . VAL D 1 251 ? 20.981 -33.914 90.526 1.00 177.74 ? 251 VAL D N 1 +ATOM 7572 C CA . VAL D 1 251 ? 21.960 -34.593 91.383 1.00 178.07 ? 251 VAL D CA 1 +ATOM 7573 C C . VAL D 1 251 ? 22.545 -35.835 90.703 1.00 175.72 ? 251 VAL D C 1 +ATOM 7574 O O . VAL D 1 251 ? 23.658 -36.261 91.024 1.00 172.05 ? 251 VAL D O 1 +ATOM 7575 C CB . VAL D 1 251 ? 21.371 -34.981 92.759 1.00 164.40 ? 251 VAL D CB 1 +ATOM 7576 C CG1 . VAL D 1 251 ? 20.781 -33.757 93.449 1.00 137.02 ? 251 VAL D CG1 1 +ATOM 7577 C CG2 . VAL D 1 251 ? 20.340 -36.098 92.628 1.00 174.87 ? 251 VAL D CG2 1 +ATOM 7578 N N . LYS D 1 252 ? 21.791 -36.412 89.772 1.00 161.69 ? 252 LYS D N 1 +ATOM 7579 C CA . LYS D 1 252 ? 22.275 -37.545 88.990 1.00 154.55 ? 252 LYS D CA 1 +ATOM 7580 C C . LYS D 1 252 ? 23.432 -37.109 88.075 1.00 163.79 ? 252 LYS D C 1 +ATOM 7581 O O . LYS D 1 252 ? 24.485 -37.752 88.026 1.00 129.02 ? 252 LYS D O 1 +ATOM 7582 C CB . LYS D 1 252 ? 21.110 -38.135 88.192 1.00 145.14 ? 252 LYS D CB 1 +ATOM 7583 C CG . LYS D 1 252 ? 21.464 -39.311 87.297 1.00 153.36 ? 252 LYS D CG 1 +ATOM 7584 C CD . LYS D 1 252 ? 20.227 -39.783 86.536 1.00 165.38 ? 252 LYS D CD 1 +ATOM 7585 C CE . LYS D 1 252 ? 20.516 -39.985 85.053 1.00 186.65 ? 252 LYS D CE 1 +ATOM 7586 N NZ . LYS D 1 252 ? 19.279 -40.187 84.249 1.00 178.60 ? 252 LYS D NZ 1 +ATOM 7587 N N . TYR D 1 253 ? 23.248 -35.981 87.391 1.00 192.65 ? 253 TYR D N 1 +ATOM 7588 C CA . TYR D 1 253 ? 24.265 -35.458 86.470 1.00 186.08 ? 253 TYR D CA 1 +ATOM 7589 C C . TYR D 1 253 ? 25.398 -34.790 87.233 1.00 176.23 ? 253 TYR D C 1 +ATOM 7590 O O . TYR D 1 253 ? 26.545 -34.792 86.784 1.00 153.16 ? 253 TYR D O 1 +ATOM 7591 C CB . TYR D 1 253 ? 23.632 -34.495 85.447 1.00 183.25 ? 253 TYR D CB 1 +ATOM 7592 C CG . TYR D 1 253 ? 22.781 -35.235 84.423 1.00 174.67 ? 253 TYR D CG 1 +ATOM 7593 C CD1 . TYR D 1 253 ? 23.363 -35.838 83.311 1.00 150.37 ? 253 TYR D CD1 1 +ATOM 7594 C CD2 . TYR D 1 253 ? 21.405 -35.393 84.605 1.00 184.32 ? 253 TYR D CD2 1 +ATOM 7595 C CE1 . TYR D 1 253 ? 22.593 -36.545 82.400 1.00 144.27 ? 253 TYR D CE1 1 +ATOM 7596 C CE2 . TYR D 1 253 ? 20.627 -36.091 83.685 1.00 160.74 ? 253 TYR D CE2 1 +ATOM 7597 C CZ . TYR D 1 253 ? 21.232 -36.667 82.589 1.00 147.99 ? 253 TYR D CZ 1 +ATOM 7598 O OH . TYR D 1 253 ? 20.481 -37.372 81.683 1.00 133.19 ? 253 TYR D OH 1 +ATOM 7599 N N . ARG D 1 254 ? 25.057 -34.197 88.376 1.00 167.16 ? 254 ARG D N 1 +ATOM 7600 C CA . ARG D 1 254 ? 26.063 -33.683 89.308 1.00 143.99 ? 254 ARG D CA 1 +ATOM 7601 C C . ARG D 1 254 ? 26.987 -34.814 89.749 1.00 142.79 ? 254 ARG D C 1 +ATOM 7602 O O . ARG D 1 254 ? 28.205 -34.626 89.845 1.00 170.00 ? 254 ARG D O 1 +ATOM 7603 C CB . ARG D 1 254 ? 25.399 -33.056 90.538 1.00 123.59 ? 254 ARG D CB 1 +ATOM 7604 C CG . ARG D 1 254 ? 26.386 -32.408 91.494 1.00 121.82 ? 254 ARG D CG 1 +ATOM 7605 C CD . ARG D 1 254 ? 25.721 -31.454 92.474 1.00 130.49 ? 254 ARG D CD 1 +ATOM 7606 N NE . ARG D 1 254 ? 25.133 -30.273 91.848 1.00 136.02 ? 254 ARG D NE 1 +ATOM 7607 C CZ . ARG D 1 254 ? 23.827 -30.044 91.707 1.00 161.77 ? 254 ARG D CZ 1 +ATOM 7608 N NH1 . ARG D 1 254 ? 22.927 -30.914 92.142 1.00 150.85 ? 254 ARG D NH1 1 +ATOM 7609 N NH2 . ARG D 1 254 ? 23.417 -28.921 91.128 1.00 185.76 ? 254 ARG D NH2 1 +ATOM 7610 N N . HIS D 1 255 ? 26.397 -35.986 89.979 1.00 147.41 ? 255 HIS D N 1 +ATOM 7611 C CA . HIS D 1 255 ? 27.149 -37.167 90.397 1.00 169.97 ? 255 HIS D CA 1 +ATOM 7612 C C . HIS D 1 255 ? 28.059 -37.706 89.295 1.00 162.22 ? 255 HIS D C 1 +ATOM 7613 O O . HIS D 1 255 ? 29.153 -38.210 89.577 1.00 142.81 ? 255 HIS D O 1 +ATOM 7614 C CB . HIS D 1 255 ? 26.204 -38.273 90.896 1.00 193.39 ? 255 HIS D CB 1 +ATOM 7615 C CG . HIS D 1 255 ? 26.195 -38.439 92.389 1.00 204.02 ? 255 HIS D CG 1 +ATOM 7616 N ND1 . HIS D 1 255 ? 25.558 -37.556 93.235 1.00 200.25 ? 255 HIS D ND1 1 +ATOM 7617 C CD2 . HIS D 1 255 ? 26.741 -39.391 93.183 1.00 196.19 ? 255 HIS D CD2 1 +ATOM 7618 C CE1 . HIS D 1 255 ? 25.714 -37.955 94.486 1.00 179.03 ? 255 HIS D CE1 1 +ATOM 7619 N NE2 . HIS D 1 255 ? 26.429 -39.066 94.482 1.00 176.95 ? 255 HIS D NE2 1 +ATOM 7620 N N . MET D 1 256 ? 27.626 -37.595 88.043 1.00 143.42 ? 256 MET D N 1 +ATOM 7621 C CA . MET D 1 256 ? 28.451 -38.080 86.933 1.00 162.35 ? 256 MET D CA 1 +ATOM 7622 C C . MET D 1 256 ? 29.713 -37.217 86.728 1.00 195.29 ? 256 MET D C 1 +ATOM 7623 O O . MET D 1 256 ? 30.728 -37.705 86.217 1.00 191.15 ? 256 MET D O 1 +ATOM 7624 C CB . MET D 1 256 ? 27.624 -38.170 85.647 1.00 147.81 ? 256 MET D CB 1 +ATOM 7625 C CG . MET D 1 256 ? 26.341 -38.983 85.802 1.00 150.03 ? 256 MET D CG 1 +ATOM 7626 S SD . MET D 1 256 ? 25.593 -39.579 84.284 1.00 130.49 ? 256 MET D SD 1 +ATOM 7627 C CE . MET D 1 256 ? 26.820 -40.786 83.765 1.00 98.36 ? 256 MET D CE 1 +ATOM 7628 N N . SER D 1 257 ? 29.662 -35.964 87.185 1.00 207.19 ? 257 SER D N 1 +ATOM 7629 C CA . SER D 1 257 ? 30.820 -35.051 87.144 1.00 179.73 ? 257 SER D CA 1 +ATOM 7630 C C . SER D 1 257 ? 31.862 -35.384 88.211 1.00 164.05 ? 257 SER D C 1 +ATOM 7631 O O . SER D 1 257 ? 32.792 -36.146 87.975 1.00 119.85 ? 257 SER D O 1 +ATOM 7632 C CB . SER D 1 257 ? 30.360 -33.598 87.338 1.00 162.15 ? 257 SER D CB 1 +ATOM 7633 O OG . SER D 1 257 ? 29.213 -33.328 86.569 1.00 169.13 ? 257 SER D OG 1 +ATOM 7634 N N . LEU E 1 2 ? 7.056 -54.243 66.401 1.00 138.26 ? 2 LEU E N 1 +ATOM 7635 C CA . LEU E 1 2 ? 8.545 -54.372 66.376 1.00 146.44 ? 2 LEU E CA 1 +ATOM 7636 C C . LEU E 1 2 ? 9.057 -54.312 64.918 1.00 153.62 ? 2 LEU E C 1 +ATOM 7637 O O . LEU E 1 2 ? 9.559 -55.309 64.350 1.00 112.22 ? 2 LEU E O 1 +ATOM 7638 C CB . LEU E 1 2 ? 8.999 -55.655 67.094 1.00 158.33 ? 2 LEU E CB 1 +ATOM 7639 C CG . LEU E 1 2 ? 8.675 -55.833 68.598 1.00 141.65 ? 2 LEU E CG 1 +ATOM 7640 C CD1 . LEU E 1 2 ? 9.192 -57.190 69.078 1.00 123.44 ? 2 LEU E CD1 1 +ATOM 7641 C CD2 . LEU E 1 2 ? 9.208 -54.713 69.498 1.00 123.05 ? 2 LEU E CD2 1 +ATOM 7642 N N . THR E 1 3 ? 8.824 -53.143 64.314 1.00 174.71 ? 3 THR E N 1 +ATOM 7643 C CA . THR E 1 3 ? 9.478 -52.686 63.081 1.00 192.36 ? 3 THR E CA 1 +ATOM 7644 C C . THR E 1 3 ? 9.780 -51.167 63.148 1.00 207.91 ? 3 THR E C 1 +ATOM 7645 O O . THR E 1 3 ? 10.339 -50.575 62.209 1.00 179.73 ? 3 THR E O 1 +ATOM 7646 C CB . THR E 1 3 ? 8.603 -52.941 61.836 1.00 174.89 ? 3 THR E CB 1 +ATOM 7647 O OG1 . THR E 1 3 ? 7.431 -52.099 61.887 1.00 133.39 ? 3 THR E OG1 1 +ATOM 7648 C CG2 . THR E 1 3 ? 8.219 -54.416 61.732 1.00 163.21 ? 3 THR E CG2 1 +ATOM 7649 N N . ALA E 1 4 ? 9.350 -50.527 64.231 1.00 190.59 ? 4 ALA E N 1 +ATOM 7650 C CA . ALA E 1 4 ? 9.889 -49.221 64.621 1.00 143.34 ? 4 ALA E CA 1 +ATOM 7651 C C . ALA E 1 4 ? 11.310 -49.439 65.210 1.00 129.75 ? 4 ALA E C 1 +ATOM 7652 O O . ALA E 1 4 ? 11.831 -50.555 65.163 1.00 88.63 ? 4 ALA E O 1 +ATOM 7653 C CB . ALA E 1 4 ? 8.938 -48.541 65.605 1.00 115.63 ? 4 ALA E CB 1 +ATOM 7654 N N . PRO E 1 5 ? 11.967 -48.381 65.726 1.00 125.76 ? 5 PRO E N 1 +ATOM 7655 C CA . PRO E 1 5 ? 13.377 -48.643 65.963 1.00 107.60 ? 5 PRO E CA 1 +ATOM 7656 C C . PRO E 1 5 ? 13.643 -49.408 67.254 1.00 119.27 ? 5 PRO E C 1 +ATOM 7657 O O . PRO E 1 5 ? 12.732 -49.605 68.062 1.00 139.12 ? 5 PRO E O 1 +ATOM 7658 C CB . PRO E 1 5 ? 13.965 -47.241 66.046 1.00 124.85 ? 5 PRO E CB 1 +ATOM 7659 C CG . PRO E 1 5 ? 12.849 -46.353 66.523 1.00 118.70 ? 5 PRO E CG 1 +ATOM 7660 C CD . PRO E 1 5 ? 11.552 -47.047 66.215 1.00 128.91 ? 5 PRO E CD 1 +ATOM 7661 N N . PRO E 1 6 ? 14.879 -49.890 67.432 1.00 157.26 ? 6 PRO E N 1 +ATOM 7662 C CA . PRO E 1 6 ? 15.329 -50.417 68.733 1.00 188.40 ? 6 PRO E CA 1 +ATOM 7663 C C . PRO E 1 6 ? 15.678 -49.307 69.716 1.00 203.31 ? 6 PRO E C 1 +ATOM 7664 O O . PRO E 1 6 ? 16.072 -48.218 69.294 1.00 229.36 ? 6 PRO E O 1 +ATOM 7665 C CB . PRO E 1 6 ? 16.571 -51.253 68.389 1.00 182.49 ? 6 PRO E CB 1 +ATOM 7666 C CG . PRO E 1 6 ? 16.986 -50.837 67.025 1.00 183.02 ? 6 PRO E CG 1 +ATOM 7667 C CD . PRO E 1 6 ? 15.847 -50.123 66.350 1.00 167.00 ? 6 PRO E CD 1 +ATOM 7668 N N . LYS E 1 7 ? 15.546 -49.581 71.013 1.00 185.80 ? 7 LYS E N 1 +ATOM 7669 C CA . LYS E 1 7 ? 15.786 -48.551 72.028 1.00 171.64 ? 7 LYS E CA 1 +ATOM 7670 C C . LYS E 1 7 ? 17.206 -48.610 72.591 1.00 154.77 ? 7 LYS E C 1 +ATOM 7671 O O . LYS E 1 7 ? 17.954 -49.569 72.328 1.00 109.74 ? 7 LYS E O 1 +ATOM 7672 C CB . LYS E 1 7 ? 14.767 -48.638 73.165 1.00 158.80 ? 7 LYS E CB 1 +ATOM 7673 C CG . LYS E 1 7 ? 13.356 -48.273 72.769 1.00 151.43 ? 7 LYS E CG 1 +ATOM 7674 C CD . LYS E 1 7 ? 12.444 -49.487 72.625 1.00 136.76 ? 7 LYS E CD 1 +ATOM 7675 C CE . LYS E 1 7 ? 10.991 -49.047 72.544 1.00 168.49 ? 7 LYS E CE 1 +ATOM 7676 N NZ . LYS E 1 7 ? 10.159 -49.994 71.753 1.00 186.23 ? 7 LYS E NZ 1 +ATOM 7677 N N . GLU E 1 8 ? 17.567 -47.559 73.336 1.00 148.14 ? 8 GLU E N 1 +ATOM 7678 C CA . GLU E 1 8 ? 18.967 -47.273 73.682 1.00 136.94 ? 8 GLU E CA 1 +ATOM 7679 C C . GLU E 1 8 ? 19.572 -48.322 74.592 1.00 121.28 ? 8 GLU E C 1 +ATOM 7680 O O . GLU E 1 8 ? 19.099 -48.546 75.696 1.00 172.05 ? 8 GLU E O 1 +ATOM 7681 C CB . GLU E 1 8 ? 19.136 -45.852 74.307 1.00 133.40 ? 8 GLU E CB 1 +ATOM 7682 C CG . GLU E 1 8 ? 18.804 -45.668 75.772 1.00 128.92 ? 8 GLU E CG 1 +ATOM 7683 C CD . GLU E 1 8 ? 19.224 -44.296 76.307 1.00 138.30 ? 8 GLU E CD 1 +ATOM 7684 O OE1 . GLU E 1 8 ? 20.414 -43.924 76.183 1.00 128.45 ? 8 GLU E OE1 1 +ATOM 7685 O OE2 . GLU E 1 8 ? 18.379 -43.596 76.898 1.00 118.40 ? 8 GLU E OE2 1 +ATOM 7686 N N . ALA E 1 9 ? 20.607 -48.985 74.098 1.00 110.65 ? 9 ALA E N 1 +ATOM 7687 C CA . ALA E 1 9 ? 21.407 -49.902 74.896 1.00 118.36 ? 9 ALA E CA 1 +ATOM 7688 C C . ALA E 1 9 ? 22.636 -49.174 75.442 1.00 137.01 ? 9 ALA E C 1 +ATOM 7689 O O . ALA E 1 9 ? 23.512 -48.770 74.674 1.00 197.32 ? 9 ALA E O 1 +ATOM 7690 C CB . ALA E 1 9 ? 21.827 -51.085 74.039 1.00 109.14 ? 9 ALA E CB 1 +ATOM 7691 N N . ALA E 1 10 ? 22.688 -49.021 76.764 1.00 118.01 ? 10 ALA E N 1 +ATOM 7692 C CA . ALA E 1 10 ? 23.680 -48.187 77.466 1.00 116.88 ? 10 ALA E CA 1 +ATOM 7693 C C . ALA E 1 10 ? 23.240 -46.721 77.487 1.00 116.70 ? 10 ALA E C 1 +ATOM 7694 O O . ALA E 1 10 ? 22.433 -46.299 76.676 1.00 95.50 ? 10 ALA E O 1 +ATOM 7695 C CB . ALA E 1 10 ? 25.094 -48.332 76.886 1.00 94.90 ? 10 ALA E CB 1 +ATOM 7696 N N . ARG E 1 11 ? 23.744 -45.945 78.439 1.00 136.59 ? 11 ARG E N 1 +ATOM 7697 C CA . ARG E 1 11 ? 23.316 -44.552 78.561 1.00 148.60 ? 11 ARG E CA 1 +ATOM 7698 C C . ARG E 1 11 ? 24.470 -43.664 78.117 1.00 158.93 ? 11 ARG E C 1 +ATOM 7699 O O . ARG E 1 11 ? 25.631 -44.061 78.214 1.00 171.19 ? 11 ARG E O 1 +ATOM 7700 C CB . ARG E 1 11 ? 22.741 -44.289 79.954 1.00 153.98 ? 11 ARG E CB 1 +ATOM 7701 C CG . ARG E 1 11 ? 21.438 -45.019 80.236 1.00 163.92 ? 11 ARG E CG 1 +ATOM 7702 C CD . ARG E 1 11 ? 20.899 -44.675 81.615 1.00 157.32 ? 11 ARG E CD 1 +ATOM 7703 N NE . ARG E 1 11 ? 19.684 -45.422 81.929 1.00 158.42 ? 11 ARG E NE 1 +ATOM 7704 C CZ . ARG E 1 11 ? 19.076 -45.395 83.110 1.00 144.07 ? 11 ARG E CZ 1 +ATOM 7705 N NH1 . ARG E 1 11 ? 19.568 -44.657 84.096 1.00 123.28 ? 11 ARG E NH1 1 +ATOM 7706 N NH2 . ARG E 1 11 ? 17.974 -46.106 83.307 1.00 138.87 ? 11 ARG E NH2 1 +ATOM 7707 N N . PRO E 1 12 ? 24.163 -42.462 77.633 1.00 166.70 ? 12 PRO E N 1 +ATOM 7708 C CA . PRO E 1 12 ? 25.223 -41.502 77.356 1.00 157.96 ? 12 PRO E CA 1 +ATOM 7709 C C . PRO E 1 12 ? 25.940 -41.135 78.645 1.00 139.57 ? 12 PRO E C 1 +ATOM 7710 O O . PRO E 1 12 ? 25.339 -40.575 79.561 1.00 124.72 ? 12 PRO E O 1 +ATOM 7711 C CB . PRO E 1 12 ? 24.476 -40.290 76.783 1.00 186.43 ? 12 PRO E CB 1 +ATOM 7712 C CG . PRO E 1 12 ? 23.097 -40.770 76.460 1.00 192.94 ? 12 PRO E CG 1 +ATOM 7713 C CD . PRO E 1 12 ? 22.827 -41.889 77.414 1.00 167.88 ? 12 PRO E CD 1 +ATOM 7714 N N . THR E 1 13 ? 27.207 -41.509 78.734 1.00 131.53 ? 13 THR E N 1 +ATOM 7715 C CA . THR E 1 13 ? 28.081 -41.026 79.796 1.00 121.64 ? 13 THR E CA 1 +ATOM 7716 C C . THR E 1 13 ? 28.844 -39.788 79.326 1.00 135.58 ? 13 THR E C 1 +ATOM 7717 O O . THR E 1 13 ? 28.982 -39.582 78.116 1.00 174.93 ? 13 THR E O 1 +ATOM 7718 C CB . THR E 1 13 ? 29.080 -42.122 80.194 1.00 101.71 ? 13 THR E CB 1 +ATOM 7719 O OG1 . THR E 1 13 ? 29.780 -41.718 81.376 1.00 121.33 ? 13 THR E OG1 1 +ATOM 7720 C CG2 . THR E 1 13 ? 30.079 -42.441 79.041 1.00 81.28 ? 13 THR E CG2 1 +ATOM 7721 N N . LEU E 1 14 ? 29.382 -38.993 80.249 1.00 114.26 ? 14 LEU E N 1 +ATOM 7722 C CA . LEU E 1 14 ? 30.358 -37.995 79.816 1.00 110.34 ? 14 LEU E CA 1 +ATOM 7723 C C . LEU E 1 14 ? 31.715 -38.686 79.510 1.00 75.50 ? 14 LEU E C 1 +ATOM 7724 O O . LEU E 1 14 ? 31.897 -39.824 79.829 1.00 52.74 ? 14 LEU E O 1 +ATOM 7725 C CB . LEU E 1 14 ? 30.489 -36.820 80.785 1.00 106.38 ? 14 LEU E CB 1 +ATOM 7726 C CG . LEU E 1 14 ? 30.817 -37.120 82.225 1.00 108.35 ? 14 LEU E CG 1 +ATOM 7727 C CD1 . LEU E 1 14 ? 31.681 -36.015 82.814 1.00 104.57 ? 14 LEU E CD1 1 +ATOM 7728 C CD2 . LEU E 1 14 ? 29.527 -37.238 82.985 1.00 113.99 ? 14 LEU E CD2 1 +ATOM 7729 N N . MET E 1 15 ? 32.540 -38.077 78.676 1.00 84.04 ? 15 MET E N 1 +ATOM 7730 C CA . MET E 1 15 ? 33.460 -38.843 77.827 1.00 96.35 ? 15 MET E CA 1 +ATOM 7731 C C . MET E 1 15 ? 34.514 -39.465 78.729 1.00 91.51 ? 15 MET E C 1 +ATOM 7732 O O . MET E 1 15 ? 35.253 -38.740 79.407 1.00 105.11 ? 15 MET E O 1 +ATOM 7733 C CB . MET E 1 15 ? 34.091 -37.963 76.698 1.00 125.94 ? 15 MET E CB 1 +ATOM 7734 C CG . MET E 1 15 ? 34.509 -38.747 75.445 1.00 107.57 ? 15 MET E CG 1 +ATOM 7735 S SD . MET E 1 15 ? 35.957 -38.225 74.475 1.00 115.69 ? 15 MET E SD 1 +ATOM 7736 C CE . MET E 1 15 ? 36.985 -37.265 75.585 1.00 85.75 ? 15 MET E CE 1 +ATOM 7737 N N . PRO E 1 16 ? 34.655 -40.797 78.654 1.00 98.57 ? 16 PRO E N 1 +ATOM 7738 C CA . PRO E 1 16 ? 35.588 -41.578 79.465 1.00 112.66 ? 16 PRO E CA 1 +ATOM 7739 C C . PRO E 1 16 ? 37.088 -41.233 79.347 1.00 108.20 ? 16 PRO E C 1 +ATOM 7740 O O . PRO E 1 16 ? 37.862 -41.943 78.686 1.00 78.90 ? 16 PRO E O 1 +ATOM 7741 C CB . PRO E 1 16 ? 35.328 -43.022 79.003 1.00 115.44 ? 16 PRO E CB 1 +ATOM 7742 C CG . PRO E 1 16 ? 34.839 -42.887 77.616 1.00 115.99 ? 16 PRO E CG 1 +ATOM 7743 C CD . PRO E 1 16 ? 34.027 -41.626 77.608 1.00 100.99 ? 16 PRO E CD 1 +ATOM 7744 N N . ARG E 1 17 ? 37.491 -40.173 80.037 1.00 101.47 ? 17 ARG E N 1 +ATOM 7745 C CA . ARG E 1 17 ? 38.898 -39.834 80.165 1.00 124.53 ? 17 ARG E CA 1 +ATOM 7746 C C . ARG E 1 17 ? 39.487 -40.571 81.372 1.00 110.31 ? 17 ARG E C 1 +ATOM 7747 O O . ARG E 1 17 ? 38.801 -40.767 82.354 1.00 142.59 ? 17 ARG E O 1 +ATOM 7748 C CB . ARG E 1 17 ? 39.050 -38.315 80.319 1.00 128.05 ? 17 ARG E CB 1 +ATOM 7749 C CG . ARG E 1 17 ? 39.123 -37.568 78.990 1.00 132.53 ? 17 ARG E CG 1 +ATOM 7750 C CD . ARG E 1 17 ? 38.856 -36.077 79.125 1.00 137.30 ? 17 ARG E CD 1 +ATOM 7751 N NE . ARG E 1 17 ? 37.438 -35.787 79.269 1.00 144.07 ? 17 ARG E NE 1 +ATOM 7752 C CZ . ARG E 1 17 ? 36.949 -34.586 79.571 1.00 147.32 ? 17 ARG E CZ 1 +ATOM 7753 N NH1 . ARG E 1 17 ? 37.769 -33.552 79.699 1.00 121.92 ? 17 ARG E NH1 1 +ATOM 7754 N NH2 . ARG E 1 17 ? 35.634 -34.418 79.694 1.00 143.27 ? 17 ARG E NH2 1 +ATOM 7755 N N . ALA E 1 18 ? 40.754 -40.967 81.302 1.00 107.64 ? 18 ALA E N 1 +ATOM 7756 C CA . ALA E 1 18 ? 41.373 -41.742 82.388 1.00 106.50 ? 18 ALA E CA 1 +ATOM 7757 C C . ALA E 1 18 ? 42.484 -40.994 83.140 1.00 104.25 ? 18 ALA E C 1 +ATOM 7758 O O . ALA E 1 18 ? 42.231 -39.940 83.727 1.00 59.45 ? 18 ALA E O 1 +ATOM 7759 C CB . ALA E 1 18 ? 41.881 -43.078 81.862 1.00 122.67 ? 18 ALA E CB 1 +ATOM 7760 N N . GLN E 1 19 ? 43.718 -41.504 83.068 1.00 118.90 ? 19 GLN E N 1 +ATOM 7761 C CA . GLN E 1 19 ? 44.756 -41.110 84.025 1.00 141.28 ? 19 GLN E CA 1 +ATOM 7762 C C . GLN E 1 19 ? 45.255 -39.679 83.810 1.00 117.62 ? 19 GLN E C 1 +ATOM 7763 O O . GLN E 1 19 ? 45.316 -38.872 84.748 1.00 77.38 ? 19 GLN E O 1 +ATOM 7764 C CB . GLN E 1 19 ? 45.940 -42.081 83.949 1.00 159.34 ? 19 GLN E CB 1 +ATOM 7765 C CG . GLN E 1 19 ? 46.998 -41.862 85.023 1.00 168.53 ? 19 GLN E CG 1 +ATOM 7766 C CD . GLN E 1 19 ? 46.426 -41.883 86.434 1.00 210.24 ? 19 GLN E CD 1 +ATOM 7767 O OE1 . GLN E 1 19 ? 45.940 -42.918 86.904 1.00 275.98 ? 19 GLN E OE1 1 +ATOM 7768 N NE2 . GLN E 1 19 ? 46.451 -40.734 87.106 1.00 205.95 ? 19 GLN E NE2 1 +ATOM 7769 N N . SER E 1 20 ? 45.616 -39.395 82.560 1.00 116.35 ? 20 SER E N 1 +ATOM 7770 C CA . SER E 1 20 ? 45.982 -38.056 82.119 1.00 107.33 ? 20 SER E CA 1 +ATOM 7771 C C . SER E 1 20 ? 45.028 -37.008 82.691 1.00 108.99 ? 20 SER E C 1 +ATOM 7772 O O . SER E 1 20 ? 45.464 -36.023 83.287 1.00 134.91 ? 20 SER E O 1 +ATOM 7773 C CB . SER E 1 20 ? 45.974 -38.001 80.582 1.00 105.80 ? 20 SER E CB 1 +ATOM 7774 O OG . SER E 1 20 ? 46.741 -39.066 80.041 1.00 131.59 ? 20 SER E OG 1 +ATOM 7775 N N . TYR E 1 21 ? 43.726 -37.237 82.516 1.00 112.10 ? 21 TYR E N 1 +ATOM 7776 C CA . TYR E 1 21 ? 42.677 -36.367 83.071 1.00 107.61 ? 21 TYR E CA 1 +ATOM 7777 C C . TYR E 1 21 ? 42.777 -36.170 84.595 1.00 120.15 ? 21 TYR E C 1 +ATOM 7778 O O . TYR E 1 21 ? 42.764 -35.033 85.089 1.00 106.64 ? 21 TYR E O 1 +ATOM 7779 C CB . TYR E 1 21 ? 41.294 -36.935 82.750 1.00 101.06 ? 21 TYR E CB 1 +ATOM 7780 C CG . TYR E 1 21 ? 40.147 -36.073 83.226 1.00 103.32 ? 21 TYR E CG 1 +ATOM 7781 C CD1 . TYR E 1 21 ? 39.799 -34.919 82.524 1.00 174.19 ? 21 TYR E CD1 1 +ATOM 7782 C CD2 . TYR E 1 21 ? 39.419 -36.391 84.362 1.00 70.59 ? 21 TYR E CD2 1 +ATOM 7783 C CE1 . TYR E 1 21 ? 38.762 -34.111 82.946 1.00 167.94 ? 21 TYR E CE1 1 +ATOM 7784 C CE2 . TYR E 1 21 ? 38.371 -35.601 84.778 1.00 74.13 ? 21 TYR E CE2 1 +ATOM 7785 C CZ . TYR E 1 21 ? 38.050 -34.453 84.068 1.00 122.01 ? 21 TYR E CZ 1 +ATOM 7786 O OH . TYR E 1 21 ? 37.072 -33.576 84.481 1.00 116.73 ? 21 TYR E OH 1 +ATOM 7787 N N . LYS E 1 22 ? 42.897 -37.274 85.325 1.00 135.22 ? 22 LYS E N 1 +ATOM 7788 C CA . LYS E 1 22 ? 42.979 -37.226 86.778 1.00 142.84 ? 22 LYS E CA 1 +ATOM 7789 C C . LYS E 1 22 ? 44.181 -36.417 87.271 1.00 132.48 ? 22 LYS E C 1 +ATOM 7790 O O . LYS E 1 22 ? 44.075 -35.664 88.243 1.00 97.86 ? 22 LYS E O 1 +ATOM 7791 C CB . LYS E 1 22 ? 43.053 -38.645 87.343 1.00 161.87 ? 22 LYS E CB 1 +ATOM 7792 C CG . LYS E 1 22 ? 41.695 -39.265 87.598 1.00 146.44 ? 22 LYS E CG 1 +ATOM 7793 C CD . LYS E 1 22 ? 41.136 -38.782 88.944 1.00 142.99 ? 22 LYS E CD 1 +ATOM 7794 C CE . LYS E 1 22 ? 41.314 -39.873 90.009 1.00 169.75 ? 22 LYS E CE 1 +ATOM 7795 N NZ . LYS E 1 22 ? 40.501 -41.080 89.699 1.00 179.89 ? 22 LYS E NZ 1 +ATOM 7796 N N . ASP E 1 23 ? 45.323 -36.605 86.616 1.00 114.70 ? 23 ASP E N 1 +ATOM 7797 C CA . ASP E 1 23 ? 46.499 -35.792 86.883 1.00 120.55 ? 23 ASP E CA 1 +ATOM 7798 C C . ASP E 1 23 ? 46.244 -34.317 86.572 1.00 127.25 ? 23 ASP E C 1 +ATOM 7799 O O . ASP E 1 23 ? 46.607 -33.430 87.350 1.00 125.81 ? 23 ASP E O 1 +ATOM 7800 C CB . ASP E 1 23 ? 47.686 -36.290 86.048 1.00 126.51 ? 23 ASP E CB 1 +ATOM 7801 C CG . ASP E 1 23 ? 48.135 -37.656 86.465 1.00 139.98 ? 23 ASP E CG 1 +ATOM 7802 O OD1 . ASP E 1 23 ? 48.205 -37.889 87.689 1.00 158.67 ? 23 ASP E OD1 1 +ATOM 7803 O OD2 . ASP E 1 23 ? 48.479 -38.468 85.583 1.00 155.34 ? 23 ASP E OD2 1 +ATOM 7804 N N . LEU E 1 24 ? 45.652 -34.069 85.407 1.00 123.53 ? 24 LEU E N 1 +ATOM 7805 C CA . LEU E 1 24 ? 45.452 -32.717 84.885 1.00 123.88 ? 24 LEU E CA 1 +ATOM 7806 C C . LEU E 1 24 ? 44.511 -31.891 85.770 1.00 143.01 ? 24 LEU E C 1 +ATOM 7807 O O . LEU E 1 24 ? 44.707 -30.675 85.934 1.00 170.62 ? 24 LEU E O 1 +ATOM 7808 C CB . LEU E 1 24 ? 44.883 -32.794 83.465 1.00 133.79 ? 24 LEU E CB 1 +ATOM 7809 C CG . LEU E 1 24 ? 44.596 -31.484 82.728 1.00 140.81 ? 24 LEU E CG 1 +ATOM 7810 C CD1 . LEU E 1 24 ? 45.846 -30.973 82.018 1.00 152.39 ? 24 LEU E CD1 1 +ATOM 7811 C CD2 . LEU E 1 24 ? 43.455 -31.675 81.733 1.00 135.13 ? 24 LEU E CD2 1 +ATOM 7812 N N . THR E 1 25 ? 43.509 -32.557 86.352 1.00 150.53 ? 25 THR E N 1 +ATOM 7813 C CA . THR E 1 25 ? 42.510 -31.883 87.197 1.00 146.14 ? 25 THR E CA 1 +ATOM 7814 C C . THR E 1 25 ? 43.055 -31.539 88.586 1.00 155.03 ? 25 THR E C 1 +ATOM 7815 O O . THR E 1 25 ? 42.917 -30.403 89.050 1.00 135.28 ? 25 THR E O 1 +ATOM 7816 C CB . THR E 1 25 ? 41.244 -32.738 87.363 1.00 131.13 ? 25 THR E CB 1 +ATOM 7817 O OG1 . THR E 1 25 ? 41.611 -34.091 87.664 1.00 132.22 ? 25 THR E OG1 1 +ATOM 7818 C CG2 . THR E 1 25 ? 40.435 -32.719 86.088 1.00 149.28 ? 25 THR E CG2 1 +ATOM 7819 N N . HIS E 1 26 ? 43.734 -32.504 89.205 1.00 159.07 ? 26 HIS E N 1 +ATOM 7820 C CA . HIS E 1 26 ? 44.278 -32.340 90.551 1.00 139.69 ? 26 HIS E CA 1 +ATOM 7821 C C . HIS E 1 26 ? 45.657 -31.669 90.528 1.00 125.85 ? 26 HIS E C 1 +ATOM 7822 O O . HIS E 1 26 ? 46.543 -31.998 91.313 1.00 158.47 ? 26 HIS E O 1 +ATOM 7823 C CB . HIS E 1 26 ? 44.332 -33.709 91.255 1.00 173.00 ? 26 HIS E CB 1 +ATOM 7824 C CG . HIS E 1 26 ? 42.975 -34.328 91.475 1.00 183.01 ? 26 HIS E CG 1 +ATOM 7825 N ND1 . HIS E 1 26 ? 42.201 -34.819 90.442 1.00 185.81 ? 26 HIS E ND1 1 +ATOM 7826 C CD2 . HIS E 1 26 ? 42.251 -34.523 92.606 1.00 156.94 ? 26 HIS E CD2 1 +ATOM 7827 C CE1 . HIS E 1 26 ? 41.070 -35.301 90.928 1.00 146.99 ? 26 HIS E CE1 1 +ATOM 7828 N NE2 . HIS E 1 26 ? 41.071 -35.126 92.237 1.00 132.29 ? 26 HIS E NE2 1 +ATOM 7829 N N . LEU E 1 27 ? 45.847 -30.720 89.625 1.00 129.89 ? 27 LEU E N 1 +ATOM 7830 C CA . LEU E 1 27 ? 47.083 -29.942 89.594 1.00 133.99 ? 27 LEU E CA 1 +ATOM 7831 C C . LEU E 1 27 ? 46.939 -28.725 90.508 1.00 137.35 ? 27 LEU E C 1 +ATOM 7832 O O . LEU E 1 27 ? 45.922 -28.041 90.468 1.00 126.89 ? 27 LEU E O 1 +ATOM 7833 C CB . LEU E 1 27 ? 47.413 -29.488 88.165 1.00 127.63 ? 27 LEU E CB 1 +ATOM 7834 C CG . LEU E 1 27 ? 48.235 -30.471 87.329 1.00 128.73 ? 27 LEU E CG 1 +ATOM 7835 C CD1 . LEU E 1 27 ? 48.226 -30.079 85.858 1.00 144.15 ? 27 LEU E CD1 1 +ATOM 7836 C CD2 . LEU E 1 27 ? 49.664 -30.562 87.839 1.00 133.72 ? 27 LEU E CD2 1 +ATOM 7837 N N . PRO E 1 28 ? 47.979 -28.431 91.306 1.00 135.12 ? 28 PRO E N 1 +ATOM 7838 C CA . PRO E 1 28 ? 47.963 -27.286 92.224 1.00 131.86 ? 28 PRO E CA 1 +ATOM 7839 C C . PRO E 1 28 ? 47.792 -25.968 91.497 1.00 150.49 ? 28 PRO E C 1 +ATOM 7840 O O . PRO E 1 28 ? 48.492 -25.723 90.522 1.00 205.20 ? 28 PRO E O 1 +ATOM 7841 C CB . PRO E 1 28 ? 49.346 -27.333 92.861 1.00 144.13 ? 28 PRO E CB 1 +ATOM 7842 C CG . PRO E 1 28 ? 50.205 -28.082 91.887 1.00 131.51 ? 28 PRO E CG 1 +ATOM 7843 C CD . PRO E 1 28 ? 49.296 -29.095 91.270 1.00 135.93 ? 28 PRO E CD 1 +ATOM 7844 N N . ALA E 1 29 ? 46.844 -25.146 91.937 1.00 152.46 ? 29 ALA E N 1 +ATOM 7845 C CA . ALA E 1 29 ? 46.392 -23.998 91.139 1.00 160.95 ? 29 ALA E CA 1 +ATOM 7846 C C . ALA E 1 29 ? 47.417 -22.845 91.145 1.00 161.07 ? 29 ALA E C 1 +ATOM 7847 O O . ALA E 1 29 ? 48.182 -22.690 92.097 1.00 142.63 ? 29 ALA E O 1 +ATOM 7848 C CB . ALA E 1 29 ? 45.031 -23.511 91.625 1.00 151.48 ? 29 ALA E CB 1 +ATOM 7849 N N . PRO E 1 30 ? 47.506 -22.098 90.027 1.00 162.15 ? 30 PRO E N 1 +ATOM 7850 C CA . PRO E 1 30 ? 48.406 -20.941 89.908 1.00 131.99 ? 30 PRO E CA 1 +ATOM 7851 C C . PRO E 1 30 ? 47.858 -19.731 90.656 1.00 112.53 ? 30 PRO E C 1 +ATOM 7852 O O . PRO E 1 30 ? 46.715 -19.779 91.144 1.00 84.60 ? 30 PRO E O 1 +ATOM 7853 C CB . PRO E 1 30 ? 48.400 -20.662 88.410 1.00 153.34 ? 30 PRO E CB 1 +ATOM 7854 C CG . PRO E 1 30 ? 47.057 -21.135 87.938 1.00 147.44 ? 30 PRO E CG 1 +ATOM 7855 C CD . PRO E 1 30 ? 46.680 -22.290 88.815 1.00 157.41 ? 30 PRO E CD 1 +ATOM 7856 N N . THR E 1 31 ? 48.622 -18.635 90.679 1.00 102.30 ? 31 THR E N 1 +ATOM 7857 C CA . THR E 1 31 ? 48.186 -17.400 91.372 1.00 129.46 ? 31 THR E CA 1 +ATOM 7858 C C . THR E 1 31 ? 46.988 -16.707 90.701 1.00 129.66 ? 31 THR E C 1 +ATOM 7859 O O . THR E 1 31 ? 46.198 -16.033 91.359 1.00 126.04 ? 31 THR E O 1 +ATOM 7860 C CB . THR E 1 31 ? 49.322 -16.360 91.525 1.00 126.82 ? 31 THR E CB 1 +ATOM 7861 O OG1 . THR E 1 31 ? 49.915 -16.079 90.253 1.00 144.34 ? 31 THR E OG1 1 +ATOM 7862 C CG2 . THR E 1 31 ? 50.387 -16.859 92.483 1.00 131.56 ? 31 THR E CG2 1 +ATOM 7863 N N . GLY E 1 32 ? 46.852 -16.899 89.396 1.00 138.74 ? 32 GLY E N 1 +ATOM 7864 C CA . GLY E 1 32 ? 45.627 -16.551 88.679 1.00 135.57 ? 32 GLY E CA 1 +ATOM 7865 C C . GLY E 1 32 ? 45.551 -17.384 87.414 1.00 133.46 ? 32 GLY E C 1 +ATOM 7866 O O . GLY E 1 32 ? 46.582 -17.873 86.939 1.00 163.00 ? 32 GLY E O 1 +ATOM 7867 N N . LYS E 1 33 ? 44.347 -17.604 86.892 1.00 100.92 ? 33 LYS E N 1 +ATOM 7868 C CA . LYS E 1 33 ? 44.233 -18.344 85.647 1.00 110.30 ? 33 LYS E CA 1 +ATOM 7869 C C . LYS E 1 33 ? 44.828 -17.528 84.494 1.00 125.29 ? 33 LYS E C 1 +ATOM 7870 O O . LYS E 1 33 ? 44.818 -16.296 84.534 1.00 114.81 ? 33 LYS E O 1 +ATOM 7871 C CB . LYS E 1 33 ? 42.786 -18.724 85.354 1.00 104.28 ? 33 LYS E CB 1 +ATOM 7872 C CG . LYS E 1 33 ? 42.375 -20.069 85.913 1.00 118.12 ? 33 LYS E CG 1 +ATOM 7873 C CD . LYS E 1 33 ? 40.883 -20.291 85.740 1.00 114.18 ? 33 LYS E CD 1 +ATOM 7874 C CE . LYS E 1 33 ? 40.363 -21.249 86.786 1.00 124.84 ? 33 LYS E CE 1 +ATOM 7875 N NZ . LYS E 1 33 ? 38.887 -21.352 86.737 1.00 140.97 ? 33 LYS E NZ 1 +ATOM 7876 N N . ILE E 1 34 ? 45.355 -18.214 83.479 1.00 138.82 ? 34 ILE E N 1 +ATOM 7877 C CA . ILE E 1 34 ? 45.995 -17.544 82.352 1.00 131.37 ? 34 ILE E CA 1 +ATOM 7878 C C . ILE E 1 34 ? 45.045 -17.608 81.138 1.00 140.85 ? 34 ILE E C 1 +ATOM 7879 O O . ILE E 1 34 ? 44.279 -18.571 80.980 1.00 132.74 ? 34 ILE E O 1 +ATOM 7880 C CB . ILE E 1 34 ? 47.408 -18.139 82.078 1.00 113.23 ? 34 ILE E CB 1 +ATOM 7881 C CG1 . ILE E 1 34 ? 48.336 -17.841 83.248 1.00 98.50 ? 34 ILE E CG1 1 +ATOM 7882 C CG2 . ILE E 1 34 ? 48.039 -17.555 80.824 1.00 129.34 ? 34 ILE E CG2 1 +ATOM 7883 C CD1 . ILE E 1 34 ? 48.840 -19.077 83.936 1.00 107.88 ? 34 ILE E CD1 1 +ATOM 7884 N N . PHE E 1 35 ? 45.012 -16.516 80.373 1.00 117.86 ? 35 PHE E N 1 +ATOM 7885 C CA . PHE E 1 35 ? 44.163 -16.389 79.201 1.00 97.07 ? 35 PHE E CA 1 +ATOM 7886 C C . PHE E 1 35 ? 44.837 -17.032 78.005 1.00 103.46 ? 35 PHE E C 1 +ATOM 7887 O O . PHE E 1 35 ? 45.939 -16.637 77.653 1.00 118.57 ? 35 PHE E O 1 +ATOM 7888 C CB . PHE E 1 35 ? 43.957 -14.917 78.907 1.00 77.19 ? 35 PHE E CB 1 +ATOM 7889 C CG . PHE E 1 35 ? 42.840 -14.294 79.683 1.00 79.63 ? 35 PHE E CG 1 +ATOM 7890 C CD1 . PHE E 1 35 ? 41.590 -14.912 79.771 1.00 84.14 ? 35 PHE E CD1 1 +ATOM 7891 C CD2 . PHE E 1 35 ? 42.984 -13.015 80.199 1.00 90.08 ? 35 PHE E CD2 1 +ATOM 7892 C CE1 . PHE E 1 35 ? 40.535 -14.298 80.429 1.00 91.73 ? 35 PHE E CE1 1 +ATOM 7893 C CE2 . PHE E 1 35 ? 41.913 -12.370 80.810 1.00 95.01 ? 35 PHE E CE2 1 +ATOM 7894 C CZ . PHE E 1 35 ? 40.692 -13.015 80.933 1.00 100.18 ? 35 PHE E CZ 1 +ATOM 7895 N N . VAL E 1 36 ? 44.162 -17.977 77.347 1.00 115.41 ? 36 VAL E N 1 +ATOM 7896 C CA . VAL E 1 36 ? 44.788 -18.705 76.214 1.00 111.44 ? 36 VAL E CA 1 +ATOM 7897 C C . VAL E 1 36 ? 43.879 -18.719 74.966 1.00 89.54 ? 36 VAL E C 1 +ATOM 7898 O O . VAL E 1 36 ? 42.661 -18.719 75.069 1.00 88.59 ? 36 VAL E O 1 +ATOM 7899 C CB . VAL E 1 36 ? 45.181 -20.188 76.548 1.00 98.89 ? 36 VAL E CB 1 +ATOM 7900 C CG1 . VAL E 1 36 ? 46.147 -20.296 77.731 1.00 85.78 ? 36 VAL E CG1 1 +ATOM 7901 C CG2 . VAL E 1 36 ? 43.910 -21.002 76.800 1.00 102.06 ? 36 VAL E CG2 1 +ATOM 7902 N N . SER E 1 37 ? 44.508 -18.796 73.806 1.00 64.20 ? 37 SER E N 1 +ATOM 7903 C CA . SER E 1 37 ? 43.797 -18.884 72.558 1.00 48.29 ? 37 SER E CA 1 +ATOM 7904 C C . SER E 1 37 ? 44.227 -20.074 71.782 1.00 46.21 ? 37 SER E C 1 +ATOM 7905 O O . SER E 1 37 ? 45.422 -20.389 71.689 1.00 53.59 ? 37 SER E O 1 +ATOM 7906 C CB . SER E 1 37 ? 44.159 -17.702 71.718 1.00 58.30 ? 37 SER E CB 1 +ATOM 7907 O OG . SER E 1 37 ? 43.557 -16.511 72.182 1.00 94.41 ? 37 SER E OG 1 +ATOM 7908 N N . VAL E 1 38 ? 43.280 -20.831 71.288 1.00 66.34 ? 38 VAL E N 1 +ATOM 7909 C CA . VAL E 1 38 ? 43.644 -21.928 70.374 1.00 114.48 ? 38 VAL E CA 1 +ATOM 7910 C C . VAL E 1 38 ? 42.891 -21.719 69.069 1.00 131.41 ? 38 VAL E C 1 +ATOM 7911 O O . VAL E 1 38 ? 41.648 -21.748 69.059 1.00 168.35 ? 38 VAL E O 1 +ATOM 7912 C CB . VAL E 1 38 ? 43.280 -23.350 70.905 1.00 138.01 ? 38 VAL E CB 1 +ATOM 7913 C CG1 . VAL E 1 38 ? 43.616 -24.402 69.859 1.00 146.06 ? 38 VAL E CG1 1 +ATOM 7914 C CG2 . VAL E 1 38 ? 43.984 -23.685 72.214 1.00 102.78 ? 38 VAL E CG2 1 +ATOM 7915 N N . TYR E 1 39 ? 43.642 -21.556 67.979 1.00 106.94 ? 39 TYR E N 1 +ATOM 7916 C CA . TYR E 1 39 ? 43.058 -21.281 66.671 1.00 84.71 ? 39 TYR E CA 1 +ATOM 7917 C C . TYR E 1 39 ? 42.825 -22.623 65.964 1.00 75.22 ? 39 TYR E C 1 +ATOM 7918 O O . TYR E 1 39 ? 41.723 -22.900 65.488 1.00 78.49 ? 39 TYR E O 1 +ATOM 7919 C CB . TYR E 1 39 ? 43.957 -20.302 65.856 1.00 84.72 ? 39 TYR E CB 1 +ATOM 7920 C CG . TYR E 1 39 ? 43.716 -18.798 66.151 1.00 78.05 ? 39 TYR E CG 1 +ATOM 7921 C CD1 . TYR E 1 39 ? 44.178 -18.204 67.337 1.00 88.31 ? 39 TYR E CD1 1 +ATOM 7922 C CD2 . TYR E 1 39 ? 43.006 -17.995 65.277 1.00 87.36 ? 39 TYR E CD2 1 +ATOM 7923 C CE1 . TYR E 1 39 ? 43.935 -16.854 67.636 1.00 59.46 ? 39 TYR E CE1 1 +ATOM 7924 C CE2 . TYR E 1 39 ? 42.712 -16.660 65.594 1.00 79.47 ? 39 TYR E CE2 1 +ATOM 7925 C CZ . TYR E 1 39 ? 43.192 -16.091 66.771 1.00 59.18 ? 39 TYR E CZ 1 +ATOM 7926 O OH . TYR E 1 39 ? 42.943 -14.783 67.040 1.00 33.10 ? 39 TYR E OH 1 +ATOM 7927 N N . ASN E 1 40 ? 43.858 -23.456 65.883 1.00 72.76 ? 40 ASN E N 1 +ATOM 7928 C CA . ASN E 1 40 ? 43.743 -24.730 65.149 1.00 83.43 ? 40 ASN E CA 1 +ATOM 7929 C C . ASN E 1 40 ? 44.917 -25.711 65.358 1.00 92.88 ? 40 ASN E C 1 +ATOM 7930 O O . ASN E 1 40 ? 46.087 -25.326 65.268 1.00 94.59 ? 40 ASN E O 1 +ATOM 7931 C CB . ASN E 1 40 ? 43.609 -24.470 63.647 1.00 91.84 ? 40 ASN E CB 1 +ATOM 7932 C CG . ASN E 1 40 ? 43.035 -25.650 62.906 1.00 91.93 ? 40 ASN E CG 1 +ATOM 7933 O OD1 . ASN E 1 40 ? 43.708 -26.265 62.068 1.00 109.47 ? 40 ASN E OD1 1 +ATOM 7934 N ND2 . ASN E 1 40 ? 41.810 -26.014 63.253 1.00 92.46 ? 40 ASN E ND2 1 +ATOM 7935 N N . ILE E 1 41 ? 44.586 -26.971 65.637 1.00 72.68 ? 41 ILE E N 1 +ATOM 7936 C CA . ILE E 1 41 ? 45.570 -28.038 65.655 1.00 72.65 ? 41 ILE E CA 1 +ATOM 7937 C C . ILE E 1 41 ? 45.208 -29.060 64.572 1.00 72.60 ? 41 ILE E C 1 +ATOM 7938 O O . ILE E 1 41 ? 44.158 -29.694 64.630 1.00 52.71 ? 41 ILE E O 1 +ATOM 7939 C CB . ILE E 1 41 ? 45.640 -28.735 67.033 1.00 89.59 ? 41 ILE E CB 1 +ATOM 7940 C CG1 . ILE E 1 41 ? 46.478 -27.925 68.040 1.00 89.08 ? 41 ILE E CG1 1 +ATOM 7941 C CG2 . ILE E 1 41 ? 46.317 -30.093 66.902 1.00 105.70 ? 41 ILE E CG2 1 +ATOM 7942 C CD1 . ILE E 1 41 ? 45.858 -26.631 68.540 1.00 68.37 ? 41 ILE E CD1 1 +ATOM 7943 N N . GLN E 1 42 ? 46.086 -29.228 63.590 1.00 78.15 ? 42 GLN E N 1 +ATOM 7944 C CA . GLN E 1 42 ? 45.733 -29.973 62.362 1.00 81.58 ? 42 GLN E CA 1 +ATOM 7945 C C . GLN E 1 42 ? 46.057 -31.430 62.471 1.00 77.55 ? 42 GLN E C 1 +ATOM 7946 O O . GLN E 1 42 ? 46.950 -31.830 63.254 1.00 108.16 ? 42 GLN E O 1 +ATOM 7947 C CB . GLN E 1 42 ? 46.482 -29.417 61.145 1.00 116.96 ? 42 GLN E CB 1 +ATOM 7948 C CG . GLN E 1 42 ? 46.086 -28.002 60.764 1.00 141.67 ? 42 GLN E CG 1 +ATOM 7949 C CD . GLN E 1 42 ? 47.255 -27.023 60.846 1.00 160.16 ? 42 GLN E CD 1 +ATOM 7950 O OE1 . GLN E 1 42 ? 48.012 -26.863 59.879 1.00 155.45 ? 42 GLN E OE1 1 +ATOM 7951 N NE2 . GLN E 1 42 ? 47.431 -26.385 62.015 1.00 128.34 ? 42 GLN E NE2 1 +ATOM 7952 N N . ASP E 1 43 ? 45.386 -32.225 61.647 1.00 67.32 ? 43 ASP E N 1 +ATOM 7953 C CA . ASP E 1 43 ? 45.747 -33.647 61.453 1.00 80.79 ? 43 ASP E CA 1 +ATOM 7954 C C . ASP E 1 43 ? 46.933 -33.791 60.486 1.00 67.74 ? 43 ASP E C 1 +ATOM 7955 O O . ASP E 1 43 ? 46.763 -34.313 59.383 1.00 43.19 ? 43 ASP E O 1 +ATOM 7956 C CB . ASP E 1 43 ? 44.521 -34.426 60.924 1.00 73.97 ? 43 ASP E CB 1 +ATOM 7957 C CG . ASP E 1 43 ? 44.724 -35.950 60.918 1.00 101.66 ? 43 ASP E CG 1 +ATOM 7958 O OD1 . ASP E 1 43 ? 45.200 -36.489 61.953 1.00 183.06 ? 43 ASP E OD1 1 +ATOM 7959 O OD2 . ASP E 1 43 ? 44.500 -36.611 59.879 1.00 63.23 ? 43 ASP E OD2 1 +ATOM 7960 N N . GLU E 1 44 ? 48.096 -33.279 60.889 1.00 60.84 ? 44 GLU E N 1 +ATOM 7961 C CA . GLU E 1 44 ? 49.253 -33.249 60.014 1.00 70.10 ? 44 GLU E CA 1 +ATOM 7962 C C . GLU E 1 44 ? 49.775 -34.683 59.706 1.00 77.46 ? 44 GLU E C 1 +ATOM 7963 O O . GLU E 1 44 ? 50.951 -34.850 59.277 1.00 61.12 ? 44 GLU E O 1 +ATOM 7964 C CB . GLU E 1 44 ? 50.362 -32.341 60.609 1.00 91.56 ? 44 GLU E CB 1 +ATOM 7965 C CG . GLU E 1 44 ? 50.279 -30.863 60.210 1.00 115.13 ? 44 GLU E CG 1 +ATOM 7966 C CD . GLU E 1 44 ? 51.369 -29.954 60.859 1.00 133.70 ? 44 GLU E CD 1 +ATOM 7967 O OE1 . GLU E 1 44 ? 52.577 -30.309 60.875 1.00 118.42 ? 44 GLU E OE1 1 +ATOM 7968 O OE2 . GLU E 1 44 ? 51.025 -28.817 61.286 1.00 89.65 ? 44 GLU E OE2 1 +ATOM 7969 N N . THR E 1 45 ? 48.953 -35.711 59.993 1.00 60.22 ? 45 THR E N 1 +ATOM 7970 C CA . THR E 1 45 ? 49.445 -37.119 60.085 1.00 56.80 ? 45 THR E CA 1 +ATOM 7971 C C . THR E 1 45 ? 49.597 -37.783 58.747 1.00 48.02 ? 45 THR E C 1 +ATOM 7972 O O . THR E 1 45 ? 50.591 -38.451 58.489 1.00 27.82 ? 45 THR E O 1 +ATOM 7973 C CB . THR E 1 45 ? 48.568 -37.996 60.997 1.00 55.29 ? 45 THR E CB 1 +ATOM 7974 O OG1 . THR E 1 45 ? 49.233 -39.242 61.247 1.00 61.28 ? 45 THR E OG1 1 +ATOM 7975 C CG2 . THR E 1 45 ? 47.242 -38.270 60.375 1.00 57.09 ? 45 THR E CG2 1 +ATOM 7976 N N . GLY E 1 46 ? 48.689 -37.453 57.844 1.00 58.89 ? 46 GLY E N 1 +ATOM 7977 C CA . GLY E 1 46 ? 48.832 -37.859 56.424 1.00 91.89 ? 46 GLY E CA 1 +ATOM 7978 C C . GLY E 1 46 ? 48.274 -39.263 56.148 1.00 118.09 ? 46 GLY E C 1 +ATOM 7979 O O . GLY E 1 46 ? 48.550 -39.920 55.145 1.00 69.81 ? 46 GLY E O 1 +ATOM 7980 N N . GLN E 1 47 ? 47.375 -39.691 56.996 1.00 150.80 ? 47 GLN E N 1 +ATOM 7981 C CA . GLN E 1 47 ? 47.121 -41.073 57.030 1.00 140.06 ? 47 GLN E CA 1 +ATOM 7982 C C . GLN E 1 47 ? 45.637 -41.366 57.064 1.00 127.55 ? 47 GLN E C 1 +ATOM 7983 O O . GLN E 1 47 ? 44.846 -40.690 57.746 1.00 129.46 ? 47 GLN E O 1 +ATOM 7984 C CB . GLN E 1 47 ? 47.837 -41.646 58.224 1.00 147.14 ? 47 GLN E CB 1 +ATOM 7985 C CG . GLN E 1 47 ? 49.361 -41.623 58.101 1.00 104.23 ? 47 GLN E CG 1 +ATOM 7986 C CD . GLN E 1 47 ? 49.858 -42.205 56.807 1.00 88.07 ? 47 GLN E CD 1 +ATOM 7987 O OE1 . GLN E 1 47 ? 49.767 -43.407 56.585 1.00 66.73 ? 47 GLN E OE1 1 +ATOM 7988 N NE2 . GLN E 1 47 ? 50.332 -41.367 55.934 1.00 91.87 ? 47 GLN E NE2 1 +ATOM 7989 N N . PHE E 1 48 ? 45.282 -42.388 56.306 1.00 121.38 ? 48 PHE E N 1 +ATOM 7990 C CA . PHE E 1 48 ? 43.910 -42.841 56.207 1.00 128.61 ? 48 PHE E CA 1 +ATOM 7991 C C . PHE E 1 48 ? 43.834 -44.317 56.546 1.00 136.03 ? 48 PHE E C 1 +ATOM 7992 O O . PHE E 1 48 ? 44.844 -45.039 56.552 1.00 139.77 ? 48 PHE E O 1 +ATOM 7993 C CB . PHE E 1 48 ? 43.363 -42.604 54.785 1.00 131.71 ? 48 PHE E CB 1 +ATOM 7994 C CG . PHE E 1 48 ? 43.236 -41.174 54.439 1.00 124.32 ? 48 PHE E CG 1 +ATOM 7995 C CD1 . PHE E 1 48 ? 44.364 -40.428 54.150 1.00 123.11 ? 48 PHE E CD1 1 +ATOM 7996 C CD2 . PHE E 1 48 ? 42.017 -40.552 54.507 1.00 123.40 ? 48 PHE E CD2 1 +ATOM 7997 C CE1 . PHE E 1 48 ? 44.282 -39.074 53.943 1.00 100.56 ? 48 PHE E CE1 1 +ATOM 7998 C CE2 . PHE E 1 48 ? 41.926 -39.202 54.270 1.00 128.33 ? 48 PHE E CE2 1 +ATOM 7999 C CZ . PHE E 1 48 ? 43.058 -38.465 53.977 1.00 101.62 ? 48 PHE E CZ 1 +ATOM 8000 N N . LYS E 1 49 ? 42.601 -44.788 56.708 1.00 119.58 ? 49 LYS E N 1 +ATOM 8001 C CA . LYS E 1 49 ? 42.358 -46.177 57.081 1.00 79.81 ? 49 LYS E CA 1 +ATOM 8002 C C . LYS E 1 49 ? 42.483 -47.030 55.847 1.00 74.63 ? 49 LYS E C 1 +ATOM 8003 O O . LYS E 1 49 ? 42.126 -46.604 54.745 1.00 83.45 ? 49 LYS E O 1 +ATOM 8004 C CB . LYS E 1 49 ? 40.990 -46.343 57.765 1.00 67.34 ? 49 LYS E CB 1 +ATOM 8005 C CG . LYS E 1 49 ? 40.916 -45.618 59.109 1.00 68.43 ? 49 LYS E CG 1 +ATOM 8006 C CD . LYS E 1 49 ? 39.685 -45.852 59.971 1.00 60.21 ? 49 LYS E CD 1 +ATOM 8007 C CE . LYS E 1 49 ? 39.933 -45.143 61.313 1.00 63.92 ? 49 LYS E CE 1 +ATOM 8008 N NZ . LYS E 1 49 ? 38.875 -45.311 62.342 1.00 68.69 ? 49 LYS E NZ 1 +ATOM 8009 N N . PRO E 1 50 ? 42.999 -48.246 56.024 1.00 94.85 ? 50 PRO E N 1 +ATOM 8010 C CA . PRO E 1 50 ? 43.117 -49.190 54.923 1.00 113.75 ? 50 PRO E CA 1 +ATOM 8011 C C . PRO E 1 50 ? 41.773 -49.849 54.545 1.00 122.60 ? 50 PRO E C 1 +ATOM 8012 O O . PRO E 1 50 ? 40.804 -49.807 55.331 1.00 111.80 ? 50 PRO E O 1 +ATOM 8013 C CB . PRO E 1 50 ? 44.125 -50.217 55.467 1.00 116.43 ? 50 PRO E CB 1 +ATOM 8014 C CG . PRO E 1 50 ? 43.931 -50.186 56.949 1.00 106.78 ? 50 PRO E CG 1 +ATOM 8015 C CD . PRO E 1 50 ? 43.534 -48.783 57.293 1.00 100.86 ? 50 PRO E CD 1 +ATOM 8016 N N . TYR E 1 51 ? 41.749 -50.513 53.394 1.00 116.58 ? 51 TYR E N 1 +ATOM 8017 C CA . TYR E 1 51 ? 40.647 -51.393 53.085 1.00 127.41 ? 51 TYR E CA 1 +ATOM 8018 C C . TYR E 1 51 ? 40.334 -52.323 54.268 1.00 152.08 ? 51 TYR E C 1 +ATOM 8019 O O . TYR E 1 51 ? 41.248 -52.907 54.855 1.00 188.99 ? 51 TYR E O 1 +ATOM 8020 C CB . TYR E 1 51 ? 40.937 -52.234 51.841 1.00 138.33 ? 51 TYR E CB 1 +ATOM 8021 C CG . TYR E 1 51 ? 39.655 -52.833 51.283 1.00 161.48 ? 51 TYR E CG 1 +ATOM 8022 C CD1 . TYR E 1 51 ? 38.833 -52.082 50.446 1.00 147.72 ? 51 TYR E CD1 1 +ATOM 8023 C CD2 . TYR E 1 51 ? 39.236 -54.121 51.626 1.00 184.80 ? 51 TYR E CD2 1 +ATOM 8024 C CE1 . TYR E 1 51 ? 37.649 -52.583 49.927 1.00 127.28 ? 51 TYR E CE1 1 +ATOM 8025 C CE2 . TYR E 1 51 ? 38.047 -54.643 51.088 1.00 174.10 ? 51 TYR E CE2 1 +ATOM 8026 C CZ . TYR E 1 51 ? 37.247 -53.841 50.268 1.00 148.16 ? 51 TYR E CZ 1 +ATOM 8027 O OH . TYR E 1 51 ? 36.068 -54.286 49.722 1.00 170.46 ? 51 TYR E OH 1 +ATOM 8028 N N . PRO E 1 52 ? 39.041 -52.493 54.614 1.00 149.98 ? 52 PRO E N 1 +ATOM 8029 C CA . PRO E 1 52 ? 37.828 -52.034 53.926 1.00 132.34 ? 52 PRO E CA 1 +ATOM 8030 C C . PRO E 1 52 ? 37.251 -50.683 54.316 1.00 118.75 ? 52 PRO E C 1 +ATOM 8031 O O . PRO E 1 52 ? 36.073 -50.439 54.029 1.00 105.75 ? 52 PRO E O 1 +ATOM 8032 C CB . PRO E 1 52 ? 36.824 -53.137 54.270 1.00 137.63 ? 52 PRO E CB 1 +ATOM 8033 C CG . PRO E 1 52 ? 37.216 -53.554 55.653 1.00 131.69 ? 52 PRO E CG 1 +ATOM 8034 C CD . PRO E 1 52 ? 38.719 -53.432 55.713 1.00 130.96 ? 52 PRO E CD 1 +ATOM 8035 N N . ALA E 1 53 ? 38.031 -49.828 54.977 1.00 101.70 ? 53 ALA E N 1 +ATOM 8036 C CA . ALA E 1 53 ? 37.524 -48.502 55.338 1.00 92.27 ? 53 ALA E CA 1 +ATOM 8037 C C . ALA E 1 53 ? 37.291 -47.682 54.100 1.00 84.88 ? 53 ALA E C 1 +ATOM 8038 O O . ALA E 1 53 ? 37.775 -48.014 52.990 1.00 70.13 ? 53 ALA E O 1 +ATOM 8039 C CB . ALA E 1 53 ? 38.479 -47.761 56.228 1.00 89.98 ? 53 ALA E CB 1 +ATOM 8040 N N . SER E 1 54 ? 36.490 -46.637 54.252 1.00 71.84 ? 54 SER E N 1 +ATOM 8041 C CA . SER E 1 54 ? 36.343 -45.745 53.128 1.00 101.42 ? 54 SER E CA 1 +ATOM 8042 C C . SER E 1 54 ? 37.725 -45.183 52.840 1.00 112.85 ? 54 SER E C 1 +ATOM 8043 O O . SER E 1 54 ? 38.498 -44.884 53.750 1.00 102.94 ? 54 SER E O 1 +ATOM 8044 C CB . SER E 1 54 ? 35.333 -44.626 53.411 1.00 131.66 ? 54 SER E CB 1 +ATOM 8045 O OG . SER E 1 54 ? 35.554 -43.464 52.611 1.00 116.58 ? 54 SER E OG 1 +ATOM 8046 N N . ASN E 1 55 ? 38.004 -44.983 51.555 1.00 132.74 ? 55 ASN E N 1 +ATOM 8047 C CA . ASN E 1 55 ? 39.223 -44.324 51.122 1.00 110.56 ? 55 ASN E CA 1 +ATOM 8048 C C . ASN E 1 55 ? 39.481 -42.992 51.856 1.00 105.96 ? 55 ASN E C 1 +ATOM 8049 O O . ASN E 1 55 ? 40.634 -42.603 52.090 1.00 112.66 ? 55 ASN E O 1 +ATOM 8050 C CB . ASN E 1 55 ? 39.139 -44.063 49.634 1.00 88.19 ? 55 ASN E CB 1 +ATOM 8051 C CG . ASN E 1 55 ? 40.486 -43.844 49.028 1.00 122.90 ? 55 ASN E CG 1 +ATOM 8052 O OD1 . ASN E 1 55 ? 41.532 -44.193 49.583 1.00 123.47 ? 55 ASN E OD1 1 +ATOM 8053 N ND2 . ASN E 1 55 ? 40.470 -43.234 47.892 1.00 165.75 ? 55 ASN E ND2 1 +ATOM 8054 N N . PHE E 1 56 ? 38.388 -42.348 52.275 1.00 116.74 ? 56 PHE E N 1 +ATOM 8055 C CA . PHE E 1 56 ? 38.425 -41.011 52.848 1.00 82.53 ? 56 PHE E CA 1 +ATOM 8056 C C . PHE E 1 56 ? 38.439 -41.020 54.356 1.00 88.55 ? 56 PHE E C 1 +ATOM 8057 O O . PHE E 1 56 ? 38.397 -39.961 54.970 1.00 123.14 ? 56 PHE E O 1 +ATOM 8058 C CB . PHE E 1 56 ? 37.174 -40.221 52.449 1.00 98.84 ? 56 PHE E CB 1 +ATOM 8059 C CG . PHE E 1 56 ? 36.968 -40.084 50.969 1.00 111.45 ? 56 PHE E CG 1 +ATOM 8060 C CD1 . PHE E 1 56 ? 37.891 -39.401 50.172 1.00 124.15 ? 56 PHE E CD1 1 +ATOM 8061 C CD2 . PHE E 1 56 ? 35.839 -40.610 50.379 1.00 86.04 ? 56 PHE E CD2 1 +ATOM 8062 C CE1 . PHE E 1 56 ? 37.700 -39.296 48.812 1.00 120.26 ? 56 PHE E CE1 1 +ATOM 8063 C CE2 . PHE E 1 56 ? 35.624 -40.464 49.024 1.00 96.91 ? 56 PHE E CE2 1 +ATOM 8064 C CZ . PHE E 1 56 ? 36.561 -39.821 48.234 1.00 109.35 ? 56 PHE E CZ 1 +ATOM 8065 N N . SER E 1 57 ? 38.370 -42.188 54.980 1.00 95.48 ? 57 SER E N 1 +ATOM 8066 C CA . SER E 1 57 ? 38.347 -42.235 56.437 1.00 89.27 ? 57 SER E CA 1 +ATOM 8067 C C . SER E 1 57 ? 39.766 -41.959 56.933 1.00 95.61 ? 57 SER E C 1 +ATOM 8068 O O . SER E 1 57 ? 40.700 -42.728 56.709 1.00 88.81 ? 57 SER E O 1 +ATOM 8069 C CB . SER E 1 57 ? 37.818 -43.576 56.943 1.00 106.15 ? 57 SER E CB 1 +ATOM 8070 O OG . SER E 1 57 ? 36.417 -43.645 56.781 1.00 135.08 ? 57 SER E OG 1 +ATOM 8071 N N . THR E 1 58 ? 39.918 -40.852 57.637 1.00 113.17 ? 58 THR E N 1 +ATOM 8072 C CA . THR E 1 58 ? 41.199 -40.495 58.205 1.00 139.07 ? 58 THR E CA 1 +ATOM 8073 C C . THR E 1 58 ? 41.566 -41.428 59.328 1.00 160.37 ? 58 THR E C 1 +ATOM 8074 O O . THR E 1 58 ? 40.716 -41.945 60.059 1.00 255.41 ? 58 THR E O 1 +ATOM 8075 C CB . THR E 1 58 ? 41.153 -39.083 58.774 1.00 164.56 ? 58 THR E CB 1 +ATOM 8076 O OG1 . THR E 1 58 ? 40.156 -39.009 59.803 1.00 172.78 ? 58 THR E OG1 1 +ATOM 8077 C CG2 . THR E 1 58 ? 40.774 -38.128 57.693 1.00 198.45 ? 58 THR E CG2 1 +ATOM 8078 N N . ALA E 1 59 ? 42.841 -41.595 59.541 1.00 133.86 ? 59 ALA E N 1 +ATOM 8079 C CA . ALA E 1 59 ? 43.216 -42.499 60.598 1.00 118.43 ? 59 ALA E CA 1 +ATOM 8080 C C . ALA E 1 59 ? 43.014 -41.879 61.983 1.00 94.49 ? 59 ALA E C 1 +ATOM 8081 O O . ALA E 1 59 ? 42.944 -42.580 62.987 1.00 59.79 ? 59 ALA E O 1 +ATOM 8082 C CB . ALA E 1 59 ? 44.636 -42.922 60.410 1.00 122.06 ? 59 ALA E CB 1 +ATOM 8083 N N . VAL E 1 60 ? 42.918 -40.552 62.024 1.00 85.18 ? 60 VAL E N 1 +ATOM 8084 C CA . VAL E 1 60 ? 42.876 -39.824 63.279 1.00 73.67 ? 60 VAL E CA 1 +ATOM 8085 C C . VAL E 1 60 ? 41.742 -38.809 63.201 1.00 93.27 ? 60 VAL E C 1 +ATOM 8086 O O . VAL E 1 60 ? 41.543 -38.165 62.164 1.00 120.59 ? 60 VAL E O 1 +ATOM 8087 C CB . VAL E 1 60 ? 44.203 -39.082 63.489 1.00 76.24 ? 60 VAL E CB 1 +ATOM 8088 C CG1 . VAL E 1 60 ? 44.210 -38.257 64.776 1.00 64.52 ? 60 VAL E CG1 1 +ATOM 8089 C CG2 . VAL E 1 60 ? 45.364 -40.071 63.472 1.00 81.10 ? 60 VAL E CG2 1 +ATOM 8090 N N . PRO E 1 61 ? 40.980 -38.647 64.296 1.00 105.72 ? 61 PRO E N 1 +ATOM 8091 C CA . PRO E 1 61 ? 39.903 -37.635 64.284 1.00 107.73 ? 61 PRO E CA 1 +ATOM 8092 C C . PRO E 1 61 ? 40.395 -36.193 64.131 1.00 102.55 ? 61 PRO E C 1 +ATOM 8093 O O . PRO E 1 61 ? 41.500 -35.856 64.606 1.00 83.68 ? 61 PRO E O 1 +ATOM 8094 C CB . PRO E 1 61 ? 39.234 -37.807 65.640 1.00 111.95 ? 61 PRO E CB 1 +ATOM 8095 C CG . PRO E 1 61 ? 40.278 -38.450 66.496 1.00 150.10 ? 61 PRO E CG 1 +ATOM 8096 C CD . PRO E 1 61 ? 41.056 -39.354 65.581 1.00 125.97 ? 61 PRO E CD 1 +ATOM 8097 N N . GLN E 1 62 ? 39.616 -35.386 63.408 1.00 91.97 ? 62 GLN E N 1 +ATOM 8098 C CA . GLN E 1 62 ? 40.053 -34.035 62.998 1.00 97.41 ? 62 GLN E CA 1 +ATOM 8099 C C . GLN E 1 62 ? 39.696 -33.060 64.074 1.00 119.79 ? 62 GLN E C 1 +ATOM 8100 O O . GLN E 1 62 ? 39.301 -31.942 63.782 1.00 158.38 ? 62 GLN E O 1 +ATOM 8101 C CB . GLN E 1 62 ? 39.401 -33.608 61.669 1.00 74.56 ? 62 GLN E CB 1 +ATOM 8102 C CG . GLN E 1 62 ? 39.560 -34.617 60.538 1.00 74.65 ? 62 GLN E CG 1 +ATOM 8103 C CD . GLN E 1 62 ? 41.006 -34.891 60.214 1.00 88.63 ? 62 GLN E CD 1 +ATOM 8104 O OE1 . GLN E 1 62 ? 41.666 -34.090 59.589 1.00 72.86 ? 62 GLN E OE1 1 +ATOM 8105 N NE2 . GLN E 1 62 ? 41.524 -36.009 60.710 1.00 127.01 ? 62 GLN E NE2 1 +ATOM 8106 N N . SER E 1 63 ? 39.750 -33.512 65.324 1.00 117.02 ? 63 SER E N 1 +ATOM 8107 C CA . SER E 1 63 ? 39.039 -32.840 66.406 1.00 136.23 ? 63 SER E CA 1 +ATOM 8108 C C . SER E 1 63 ? 39.994 -32.345 67.500 1.00 119.90 ? 63 SER E C 1 +ATOM 8109 O O . SER E 1 63 ? 39.553 -31.933 68.582 1.00 119.88 ? 63 SER E O 1 +ATOM 8110 C CB . SER E 1 63 ? 37.944 -33.771 66.977 1.00 141.07 ? 63 SER E CB 1 +ATOM 8111 O OG . SER E 1 63 ? 38.465 -34.964 67.549 1.00 128.19 ? 63 SER E OG 1 +ATOM 8112 N N . ALA E 1 64 ? 41.289 -32.377 67.198 1.00 80.96 ? 64 ALA E N 1 +ATOM 8113 C CA . ALA E 1 64 ? 42.315 -32.183 68.215 1.00 92.68 ? 64 ALA E CA 1 +ATOM 8114 C C . ALA E 1 64 ? 42.216 -30.814 68.864 1.00 85.80 ? 64 ALA E C 1 +ATOM 8115 O O . ALA E 1 64 ? 42.401 -30.660 70.087 1.00 92.24 ? 64 ALA E O 1 +ATOM 8116 C CB . ALA E 1 64 ? 43.664 -32.367 67.574 1.00 99.73 ? 64 ALA E CB 1 +ATOM 8117 N N . THR E 1 65 ? 41.858 -29.827 68.048 1.00 71.65 ? 65 THR E N 1 +ATOM 8118 C CA . THR E 1 65 ? 41.688 -28.442 68.514 1.00 59.21 ? 65 THR E CA 1 +ATOM 8119 C C . THR E 1 65 ? 40.751 -28.311 69.707 1.00 72.47 ? 65 THR E C 1 +ATOM 8120 O O . THR E 1 65 ? 41.095 -27.716 70.725 1.00 103.21 ? 65 THR E O 1 +ATOM 8121 C CB . THR E 1 65 ? 41.089 -27.608 67.422 1.00 58.06 ? 65 THR E CB 1 +ATOM 8122 O OG1 . THR E 1 65 ? 41.631 -28.034 66.161 1.00 65.41 ? 65 THR E OG1 1 +ATOM 8123 C CG2 . THR E 1 65 ? 41.333 -26.138 67.675 1.00 48.82 ? 65 THR E CG2 1 +ATOM 8124 N N . ALA E 1 66 ? 39.589 -28.955 69.615 1.00 101.00 ? 66 ALA E N 1 +ATOM 8125 C CA . ALA E 1 66 ? 38.589 -28.856 70.665 1.00 92.25 ? 66 ALA E CA 1 +ATOM 8126 C C . ALA E 1 66 ? 39.029 -29.643 71.909 1.00 74.62 ? 66 ALA E C 1 +ATOM 8127 O O . ALA E 1 66 ? 38.771 -29.220 73.046 1.00 79.04 ? 66 ALA E O 1 +ATOM 8128 C CB . ALA E 1 66 ? 37.247 -29.339 70.157 1.00 82.95 ? 66 ALA E CB 1 +ATOM 8129 N N . MET E 1 67 ? 39.740 -30.736 71.683 1.00 59.94 ? 67 MET E N 1 +ATOM 8130 C CA . MET E 1 67 ? 40.260 -31.509 72.781 1.00 84.59 ? 67 MET E CA 1 +ATOM 8131 C C . MET E 1 67 ? 41.255 -30.667 73.571 1.00 81.86 ? 67 MET E C 1 +ATOM 8132 O O . MET E 1 67 ? 41.310 -30.752 74.824 1.00 130.50 ? 67 MET E O 1 +ATOM 8133 C CB . MET E 1 67 ? 40.935 -32.808 72.276 1.00 99.87 ? 67 MET E CB 1 +ATOM 8134 C CG . MET E 1 67 ? 39.983 -33.875 71.727 1.00 114.14 ? 67 MET E CG 1 +ATOM 8135 S SD . MET E 1 67 ? 40.884 -35.193 70.855 1.00 59.64 ? 67 MET E SD 1 +ATOM 8136 C CE . MET E 1 67 ? 39.552 -36.332 70.499 1.00 94.35 ? 67 MET E CE 1 +ATOM 8137 N N . LEU E 1 68 ? 42.114 -29.957 72.848 1.00 62.15 ? 68 LEU E N 1 +ATOM 8138 C CA . LEU E 1 68 ? 43.137 -29.169 73.494 1.00 71.62 ? 68 LEU E CA 1 +ATOM 8139 C C . LEU E 1 68 ? 42.517 -28.054 74.301 1.00 73.80 ? 68 LEU E C 1 +ATOM 8140 O O . LEU E 1 68 ? 42.918 -27.822 75.445 1.00 139.03 ? 68 LEU E O 1 +ATOM 8141 C CB . LEU E 1 68 ? 44.101 -28.557 72.494 1.00 80.50 ? 68 LEU E CB 1 +ATOM 8142 C CG . LEU E 1 68 ? 45.048 -27.509 73.122 1.00 102.74 ? 68 LEU E CG 1 +ATOM 8143 C CD1 . LEU E 1 68 ? 46.032 -28.159 74.120 1.00 89.54 ? 68 LEU E CD1 1 +ATOM 8144 C CD2 . LEU E 1 68 ? 45.816 -26.740 72.062 1.00 111.20 ? 68 LEU E CD2 1 +ATOM 8145 N N . VAL E 1 69 ? 41.535 -27.385 73.734 1.00 78.46 ? 69 VAL E N 1 +ATOM 8146 C CA . VAL E 1 69 ? 40.840 -26.319 74.451 1.00 97.22 ? 69 VAL E CA 1 +ATOM 8147 C C . VAL E 1 69 ? 40.229 -26.876 75.739 1.00 97.93 ? 69 VAL E C 1 +ATOM 8148 O O . VAL E 1 69 ? 40.304 -26.255 76.802 1.00 94.26 ? 69 VAL E O 1 +ATOM 8149 C CB . VAL E 1 69 ? 39.710 -25.647 73.591 1.00 91.23 ? 69 VAL E CB 1 +ATOM 8150 C CG1 . VAL E 1 69 ? 38.910 -24.664 74.434 1.00 66.01 ? 69 VAL E CG1 1 +ATOM 8151 C CG2 . VAL E 1 69 ? 40.297 -24.923 72.380 1.00 106.01 ? 69 VAL E CG2 1 +ATOM 8152 N N . THR E 1 70 ? 39.601 -28.040 75.622 1.00 97.75 ? 70 THR E N 1 +ATOM 8153 C CA . THR E 1 70 ? 38.937 -28.671 76.757 1.00 111.77 ? 70 THR E CA 1 +ATOM 8154 C C . THR E 1 70 ? 39.947 -29.019 77.838 1.00 107.28 ? 70 THR E C 1 +ATOM 8155 O O . THR E 1 70 ? 39.729 -28.780 79.025 1.00 107.01 ? 70 THR E O 1 +ATOM 8156 C CB . THR E 1 70 ? 38.161 -29.931 76.310 1.00 105.56 ? 70 THR E CB 1 +ATOM 8157 O OG1 . THR E 1 70 ? 37.239 -29.551 75.277 1.00 156.84 ? 70 THR E OG1 1 +ATOM 8158 C CG2 . THR E 1 70 ? 37.398 -30.549 77.486 1.00 93.28 ? 70 THR E CG2 1 +ATOM 8159 N N . ALA E 1 71 ? 41.061 -29.597 77.422 1.00 104.45 ? 71 ALA E N 1 +ATOM 8160 C CA . ALA E 1 71 ? 42.108 -29.946 78.365 1.00 104.38 ? 71 ALA E CA 1 +ATOM 8161 C C . ALA E 1 71 ? 42.611 -28.684 79.073 1.00 84.82 ? 71 ALA E C 1 +ATOM 8162 O O . ALA E 1 71 ? 42.923 -28.701 80.268 1.00 87.81 ? 71 ALA E O 1 +ATOM 8163 C CB . ALA E 1 71 ? 43.245 -30.701 77.645 1.00 102.15 ? 71 ALA E CB 1 +ATOM 8164 N N . LEU E 1 72 ? 42.812 -27.625 78.299 1.00 91.40 ? 72 LEU E N 1 +ATOM 8165 C CA . LEU E 1 72 ? 43.330 -26.377 78.850 1.00 111.06 ? 72 LEU E CA 1 +ATOM 8166 C C . LEU E 1 72 ? 42.361 -25.848 79.894 1.00 113.88 ? 72 LEU E C 1 +ATOM 8167 O O . LEU E 1 72 ? 42.766 -25.082 80.781 1.00 101.27 ? 72 LEU E O 1 +ATOM 8168 C CB . LEU E 1 72 ? 43.548 -25.330 77.744 1.00 124.23 ? 72 LEU E CB 1 +ATOM 8169 C CG . LEU E 1 72 ? 44.707 -25.617 76.784 1.00 105.99 ? 72 LEU E CG 1 +ATOM 8170 C CD1 . LEU E 1 72 ? 44.513 -24.771 75.535 1.00 130.94 ? 72 LEU E CD1 1 +ATOM 8171 C CD2 . LEU E 1 72 ? 46.059 -25.359 77.408 1.00 60.99 ? 72 LEU E CD2 1 +ATOM 8172 N N . LYS E 1 73 ? 41.086 -26.209 79.768 1.00 96.12 ? 73 LYS E N 1 +ATOM 8173 C CA . LYS E 1 73 ? 40.089 -25.703 80.703 1.00 103.11 ? 73 LYS E CA 1 +ATOM 8174 C C . LYS E 1 73 ? 40.057 -26.568 81.930 1.00 80.90 ? 73 LYS E C 1 +ATOM 8175 O O . LYS E 1 73 ? 39.982 -26.051 83.045 1.00 90.13 ? 73 LYS E O 1 +ATOM 8176 C CB . LYS E 1 73 ? 38.700 -25.642 80.067 1.00 127.31 ? 73 LYS E CB 1 +ATOM 8177 C CG . LYS E 1 73 ? 37.656 -24.875 80.892 1.00 131.91 ? 73 LYS E CG 1 +ATOM 8178 C CD . LYS E 1 73 ? 36.282 -24.848 80.185 1.00 116.62 ? 73 LYS E CD 1 +ATOM 8179 C CE . LYS E 1 73 ? 35.131 -24.736 81.164 1.00 120.74 ? 73 LYS E CE 1 +ATOM 8180 N NZ . LYS E 1 73 ? 34.395 -23.452 81.038 1.00 119.83 ? 73 LYS E NZ 1 +ATOM 8181 N N . ASP E 1 74 ? 40.081 -27.877 81.720 1.00 69.95 ? 74 ASP E N 1 +ATOM 8182 C CA . ASP E 1 74 ? 39.951 -28.816 82.826 1.00 92.88 ? 74 ASP E CA 1 +ATOM 8183 C C . ASP E 1 74 ? 41.100 -28.679 83.829 1.00 77.35 ? 74 ASP E C 1 +ATOM 8184 O O . ASP E 1 74 ? 40.925 -28.941 85.023 1.00 65.17 ? 74 ASP E O 1 +ATOM 8185 C CB . ASP E 1 74 ? 39.894 -30.261 82.307 1.00 104.64 ? 74 ASP E CB 1 +ATOM 8186 C CG . ASP E 1 74 ? 38.589 -30.583 81.556 1.00 118.85 ? 74 ASP E CG 1 +ATOM 8187 O OD1 . ASP E 1 74 ? 37.518 -29.978 81.851 1.00 133.20 ? 74 ASP E OD1 1 +ATOM 8188 O OD2 . ASP E 1 74 ? 38.643 -31.479 80.686 1.00 86.49 ? 74 ASP E OD2 1 +ATOM 8189 N N . SER E 1 75 ? 42.250 -28.230 83.344 1.00 80.56 ? 75 SER E N 1 +ATOM 8190 C CA . SER E 1 75 ? 43.457 -28.078 84.177 1.00 71.72 ? 75 SER E CA 1 +ATOM 8191 C C . SER E 1 75 ? 43.289 -27.030 85.276 1.00 79.47 ? 75 SER E C 1 +ATOM 8192 O O . SER E 1 75 ? 43.981 -27.084 86.287 1.00 89.41 ? 75 SER E O 1 +ATOM 8193 C CB . SER E 1 75 ? 44.666 -27.695 83.311 1.00 64.06 ? 75 SER E CB 1 +ATOM 8194 O OG . SER E 1 75 ? 44.730 -26.292 83.106 1.00 53.51 ? 75 SER E OG 1 +ATOM 8195 N N . ARG E 1 76 ? 42.391 -26.067 85.048 1.00 95.59 ? 76 ARG E N 1 +ATOM 8196 C CA . ARG E 1 76 ? 42.129 -24.945 85.966 1.00 97.19 ? 76 ARG E CA 1 +ATOM 8197 C C . ARG E 1 76 ? 43.352 -24.080 86.106 1.00 99.95 ? 76 ARG E C 1 +ATOM 8198 O O . ARG E 1 76 ? 43.656 -23.564 87.178 1.00 117.98 ? 76 ARG E O 1 +ATOM 8199 C CB . ARG E 1 76 ? 41.663 -25.440 87.327 1.00 107.40 ? 76 ARG E CB 1 +ATOM 8200 C CG . ARG E 1 76 ? 40.359 -26.225 87.304 1.00 121.16 ? 76 ARG E CG 1 +ATOM 8201 C CD . ARG E 1 76 ? 39.967 -26.637 88.717 1.00 152.04 ? 76 ARG E CD 1 +ATOM 8202 N NE . ARG E 1 76 ? 40.880 -27.654 89.254 1.00 224.61 ? 76 ARG E NE 1 +ATOM 8203 C CZ . ARG E 1 76 ? 41.956 -27.412 90.008 1.00 242.13 ? 76 ARG E CZ 1 +ATOM 8204 N NH1 . ARG E 1 76 ? 42.295 -26.171 90.348 1.00 241.88 ? 76 ARG E NH1 1 +ATOM 8205 N NH2 . ARG E 1 76 ? 42.702 -28.428 90.424 1.00 232.36 ? 76 ARG E NH2 1 +ATOM 8206 N N . TRP E 1 77 ? 44.079 -23.967 85.008 1.00 107.36 ? 77 TRP E N 1 +ATOM 8207 C CA . TRP E 1 77 ? 45.177 -23.020 84.902 1.00 131.92 ? 77 TRP E CA 1 +ATOM 8208 C C . TRP E 1 77 ? 44.828 -21.910 83.891 1.00 134.10 ? 77 TRP E C 1 +ATOM 8209 O O . TRP E 1 77 ? 45.283 -20.770 84.014 1.00 139.84 ? 77 TRP E O 1 +ATOM 8210 C CB . TRP E 1 77 ? 46.449 -23.763 84.472 1.00 128.54 ? 77 TRP E CB 1 +ATOM 8211 C CG . TRP E 1 77 ? 47.281 -24.213 85.596 1.00 120.57 ? 77 TRP E CG 1 +ATOM 8212 C CD1 . TRP E 1 77 ? 47.045 -25.270 86.407 1.00 144.43 ? 77 TRP E CD1 1 +ATOM 8213 C CD2 . TRP E 1 77 ? 48.519 -23.640 86.032 1.00 129.04 ? 77 TRP E CD2 1 +ATOM 8214 N NE1 . TRP E 1 77 ? 48.060 -25.401 87.321 1.00 173.49 ? 77 TRP E NE1 1 +ATOM 8215 C CE2 . TRP E 1 77 ? 48.979 -24.409 87.110 1.00 142.83 ? 77 TRP E CE2 1 +ATOM 8216 C CE3 . TRP E 1 77 ? 49.285 -22.556 85.612 1.00 136.44 ? 77 TRP E CE3 1 +ATOM 8217 C CZ2 . TRP E 1 77 ? 50.175 -24.127 87.778 1.00 126.86 ? 77 TRP E CZ2 1 +ATOM 8218 C CZ3 . TRP E 1 77 ? 50.466 -22.268 86.291 1.00 122.00 ? 77 TRP E CZ3 1 +ATOM 8219 C CH2 . TRP E 1 77 ? 50.896 -23.050 87.359 1.00 110.07 ? 77 TRP E CH2 1 +ATOM 8220 N N . PHE E 1 78 ? 44.069 -22.278 82.859 1.00 101.97 ? 78 PHE E N 1 +ATOM 8221 C CA . PHE E 1 78 ? 43.820 -21.415 81.719 1.00 74.47 ? 78 PHE E CA 1 +ATOM 8222 C C . PHE E 1 78 ? 42.323 -21.158 81.545 1.00 88.70 ? 78 PHE E C 1 +ATOM 8223 O O . PHE E 1 78 ? 41.498 -22.086 81.668 1.00 111.81 ? 78 PHE E O 1 +ATOM 8224 C CB . PHE E 1 78 ? 44.350 -22.079 80.435 1.00 78.52 ? 78 PHE E CB 1 +ATOM 8225 C CG . PHE E 1 78 ? 45.807 -22.447 80.483 1.00 67.49 ? 78 PHE E CG 1 +ATOM 8226 C CD1 . PHE E 1 78 ? 46.784 -21.480 80.379 1.00 73.80 ? 78 PHE E CD1 1 +ATOM 8227 C CD2 . PHE E 1 78 ? 46.180 -23.768 80.549 1.00 79.52 ? 78 PHE E CD2 1 +ATOM 8228 C CE1 . PHE E 1 78 ? 48.116 -21.811 80.417 1.00 85.48 ? 78 PHE E CE1 1 +ATOM 8229 C CE2 . PHE E 1 78 ? 47.510 -24.115 80.598 1.00 96.76 ? 78 PHE E CE2 1 +ATOM 8230 C CZ . PHE E 1 78 ? 48.482 -23.135 80.522 1.00 98.95 ? 78 PHE E CZ 1 +ATOM 8231 N N . ILE E 1 79 ? 41.996 -19.939 81.130 1.00 84.17 ? 79 ILE E N 1 +ATOM 8232 C CA . ILE E 1 79 ? 40.710 -19.620 80.517 1.00 99.94 ? 79 ILE E CA 1 +ATOM 8233 C C . ILE E 1 79 ? 40.892 -19.632 79.002 1.00 97.67 ? 79 ILE E C 1 +ATOM 8234 O O . ILE E 1 79 ? 41.784 -18.958 78.476 1.00 104.85 ? 79 ILE E O 1 +ATOM 8235 C CB . ILE E 1 79 ? 40.261 -18.210 80.912 1.00 127.13 ? 79 ILE E CB 1 +ATOM 8236 C CG1 . ILE E 1 79 ? 40.397 -18.005 82.419 1.00 149.65 ? 79 ILE E CG1 1 +ATOM 8237 C CG2 . ILE E 1 79 ? 38.823 -17.957 80.478 1.00 143.29 ? 79 ILE E CG2 1 +ATOM 8238 C CD1 . ILE E 1 79 ? 40.523 -16.550 82.826 1.00 150.34 ? 79 ILE E CD1 1 +ATOM 8239 N N . PRO E 1 80 ? 40.106 -20.459 78.299 1.00 97.65 ? 80 PRO E N 1 +ATOM 8240 C CA . PRO E 1 80 ? 40.274 -20.433 76.868 1.00 91.15 ? 80 PRO E CA 1 +ATOM 8241 C C . PRO E 1 80 ? 39.339 -19.417 76.261 1.00 69.61 ? 80 PRO E C 1 +ATOM 8242 O O . PRO E 1 80 ? 38.179 -19.356 76.627 1.00 51.49 ? 80 PRO E O 1 +ATOM 8243 C CB . PRO E 1 80 ? 39.902 -21.851 76.441 1.00 93.48 ? 80 PRO E CB 1 +ATOM 8244 C CG . PRO E 1 80 ? 40.125 -22.671 77.648 1.00 94.34 ? 80 PRO E CG 1 +ATOM 8245 C CD . PRO E 1 80 ? 39.625 -21.773 78.743 1.00 106.37 ? 80 PRO E CD 1 +ATOM 8246 N N . LEU E 1 81 ? 39.875 -18.616 75.358 1.00 56.95 ? 81 LEU E N 1 +ATOM 8247 C CA . LEU E 1 81 ? 39.081 -17.722 74.593 1.00 50.81 ? 81 LEU E CA 1 +ATOM 8248 C C . LEU E 1 81 ? 38.728 -18.419 73.284 1.00 48.08 ? 81 LEU E C 1 +ATOM 8249 O O . LEU E 1 81 ? 39.533 -19.154 72.691 1.00 35.06 ? 81 LEU E O 1 +ATOM 8250 C CB . LEU E 1 81 ? 39.852 -16.449 74.378 1.00 64.74 ? 81 LEU E CB 1 +ATOM 8251 C CG . LEU E 1 81 ? 40.318 -15.857 75.701 1.00 92.64 ? 81 LEU E CG 1 +ATOM 8252 C CD1 . LEU E 1 81 ? 41.205 -14.662 75.417 1.00 112.26 ? 81 LEU E CD1 1 +ATOM 8253 C CD2 . LEU E 1 81 ? 39.135 -15.447 76.549 1.00 96.35 ? 81 LEU E CD2 1 +ATOM 8254 N N . GLU E 1 82 ? 37.488 -18.195 72.867 1.00 62.29 ? 82 GLU E N 1 +ATOM 8255 C CA . GLU E 1 82 ? 36.913 -18.827 71.659 1.00 64.32 ? 82 GLU E CA 1 +ATOM 8256 C C . GLU E 1 82 ? 37.457 -18.121 70.415 1.00 83.62 ? 82 GLU E C 1 +ATOM 8257 O O . GLU E 1 82 ? 37.040 -16.972 70.084 1.00 109.71 ? 82 GLU E O 1 +ATOM 8258 C CB . GLU E 1 82 ? 35.344 -18.836 71.679 1.00 47.54 ? 82 GLU E CB 1 +ATOM 8259 C CG . GLU E 1 82 ? 34.685 -19.425 70.454 1.00 38.22 ? 82 GLU E CG 1 +ATOM 8260 C CD . GLU E 1 82 ? 34.881 -20.936 70.268 1.00 51.70 ? 82 GLU E CD 1 +ATOM 8261 O OE1 . GLU E 1 82 ? 36.015 -21.503 70.407 1.00 91.23 ? 82 GLU E OE1 1 +ATOM 8262 O OE2 . GLU E 1 82 ? 33.891 -21.635 69.980 1.00 66.78 ? 82 GLU E OE2 1 +ATOM 8263 N N . ARG E 1 83 ? 38.360 -18.822 69.723 1.00 64.24 ? 83 ARG E N 1 +ATOM 8264 C CA . ARG E 1 83 ? 38.794 -18.420 68.397 1.00 67.10 ? 83 ARG E CA 1 +ATOM 8265 C C . ARG E 1 83 ? 38.439 -19.420 67.253 1.00 107.45 ? 83 ARG E C 1 +ATOM 8266 O O . ARG E 1 83 ? 38.456 -19.062 66.075 1.00 140.95 ? 83 ARG E O 1 +ATOM 8267 C CB . ARG E 1 83 ? 40.277 -18.160 68.453 1.00 45.75 ? 83 ARG E CB 1 +ATOM 8268 C CG . ARG E 1 83 ? 40.648 -17.174 69.512 1.00 43.18 ? 83 ARG E CG 1 +ATOM 8269 C CD . ARG E 1 83 ? 40.194 -15.781 69.202 1.00 56.21 ? 83 ARG E CD 1 +ATOM 8270 N NE . ARG E 1 83 ? 40.841 -14.897 70.188 1.00 69.23 ? 83 ARG E NE 1 +ATOM 8271 C CZ . ARG E 1 83 ? 40.242 -14.314 71.241 1.00 68.91 ? 83 ARG E CZ 1 +ATOM 8272 N NH1 . ARG E 1 83 ? 38.928 -14.488 71.456 1.00 80.13 ? 83 ARG E NH1 1 +ATOM 8273 N NH2 . ARG E 1 83 ? 40.966 -13.517 72.046 1.00 53.65 ? 83 ARG E NH2 1 +ATOM 8274 N N . GLN E 1 84 ? 38.102 -20.662 67.580 1.00 134.94 ? 84 GLN E N 1 +ATOM 8275 C CA . GLN E 1 84 ? 37.764 -21.654 66.556 1.00 106.20 ? 84 GLN E CA 1 +ATOM 8276 C C . GLN E 1 84 ? 36.441 -21.421 65.803 1.00 66.95 ? 84 GLN E C 1 +ATOM 8277 O O . GLN E 1 84 ? 36.024 -22.164 64.873 1.00 55.48 ? 84 GLN E O 1 +ATOM 8278 C CB . GLN E 1 84 ? 37.504 -22.971 67.257 1.00 127.59 ? 84 GLN E CB 1 +ATOM 8279 C CG . GLN E 1 84 ? 36.883 -23.938 66.209 1.00 143.17 ? 84 GLN E CG 1 +ATOM 8280 C CD . GLN E 1 84 ? 37.637 -25.214 65.905 1.00 134.91 ? 84 GLN E CD 1 +ATOM 8281 O OE1 . GLN E 1 84 ? 38.771 -25.415 66.313 1.00 132.59 ? 84 GLN E OE1 1 +ATOM 8282 N NE2 . GLN E 1 84 ? 36.988 -26.076 65.143 1.00 129.05 ? 84 GLN E NE2 1 +ATOM 8283 N N . GLY E 1 85 ? 35.633 -20.634 66.413 1.00 54.90 ? 85 GLY E N 1 +ATOM 8284 C CA . GLY E 1 85 ? 34.544 -20.117 65.656 1.00 93.51 ? 85 GLY E CA 1 +ATOM 8285 C C . GLY E 1 85 ? 34.433 -18.602 65.641 1.00 95.81 ? 85 GLY E C 1 +ATOM 8286 O O . GLY E 1 85 ? 33.316 -18.063 65.824 1.00 91.73 ? 85 GLY E O 1 +ATOM 8287 N N . LEU E 1 86 ? 35.563 -17.912 65.517 1.00 57.52 ? 86 LEU E N 1 +ATOM 8288 C CA . LEU E 1 86 ? 35.590 -16.496 65.860 1.00 64.98 ? 86 LEU E CA 1 +ATOM 8289 C C . LEU E 1 86 ? 34.602 -15.749 64.995 1.00 72.74 ? 86 LEU E C 1 +ATOM 8290 O O . LEU E 1 86 ? 34.035 -14.716 65.399 1.00 106.76 ? 86 LEU E O 1 +ATOM 8291 C CB . LEU E 1 86 ? 37.002 -15.929 65.673 1.00 97.93 ? 86 LEU E CB 1 +ATOM 8292 C CG . LEU E 1 86 ? 37.275 -14.396 65.744 1.00 96.35 ? 86 LEU E CG 1 +ATOM 8293 C CD1 . LEU E 1 86 ? 36.889 -13.778 67.078 1.00 55.25 ? 86 LEU E CD1 1 +ATOM 8294 C CD2 . LEU E 1 86 ? 38.752 -14.126 65.441 1.00 108.38 ? 86 LEU E CD2 1 +ATOM 8295 N N . GLN E 1 87 ? 34.438 -16.215 63.761 1.00 88.51 ? 87 GLN E N 1 +ATOM 8296 C CA . GLN E 1 87 ? 33.629 -15.488 62.775 1.00 110.68 ? 87 GLN E CA 1 +ATOM 8297 C C . GLN E 1 87 ? 32.152 -15.359 63.240 1.00 105.31 ? 87 GLN E C 1 +ATOM 8298 O O . GLN E 1 87 ? 31.544 -14.276 63.164 1.00 61.44 ? 87 GLN E O 1 +ATOM 8299 C CB . GLN E 1 87 ? 33.737 -16.169 61.401 1.00 113.87 ? 87 GLN E CB 1 +ATOM 8300 C CG . GLN E 1 87 ? 33.673 -15.200 60.226 1.00 117.65 ? 87 GLN E CG 1 +ATOM 8301 C CD . GLN E 1 87 ? 34.503 -13.927 60.430 1.00 114.17 ? 87 GLN E CD 1 +ATOM 8302 O OE1 . GLN E 1 87 ? 35.714 -13.986 60.649 1.00 95.02 ? 87 GLN E OE1 1 +ATOM 8303 N NE2 . GLN E 1 87 ? 33.848 -12.768 60.336 1.00 101.17 ? 87 GLN E NE2 1 +ATOM 8304 N N . ASN E 1 88 ? 31.633 -16.445 63.814 1.00 103.99 ? 88 ASN E N 1 +ATOM 8305 C CA . ASN E 1 88 ? 30.279 -16.460 64.347 1.00 95.86 ? 88 ASN E CA 1 +ATOM 8306 C C . ASN E 1 88 ? 30.126 -15.564 65.564 1.00 82.71 ? 88 ASN E C 1 +ATOM 8307 O O . ASN E 1 88 ? 29.088 -14.909 65.743 1.00 71.75 ? 88 ASN E O 1 +ATOM 8308 C CB . ASN E 1 88 ? 29.911 -17.866 64.780 1.00 99.56 ? 88 ASN E CB 1 +ATOM 8309 C CG . ASN E 1 88 ? 30.077 -18.856 63.673 1.00 89.48 ? 88 ASN E CG 1 +ATOM 8310 O OD1 . ASN E 1 88 ? 29.737 -18.551 62.518 1.00 128.25 ? 88 ASN E OD1 1 +ATOM 8311 N ND2 . ASN E 1 88 ? 30.561 -20.043 63.998 1.00 56.49 ? 88 ASN E ND2 1 +ATOM 8312 N N . LEU E 1 89 ? 31.162 -15.552 66.401 1.00 64.39 ? 89 LEU E N 1 +ATOM 8313 C CA . LEU E 1 89 ? 31.190 -14.695 67.555 1.00 57.22 ? 89 LEU E CA 1 +ATOM 8314 C C . LEU E 1 89 ? 31.063 -13.207 67.135 1.00 74.28 ? 89 LEU E C 1 +ATOM 8315 O O . LEU E 1 89 ? 30.261 -12.425 67.681 1.00 79.12 ? 89 LEU E O 1 +ATOM 8316 C CB . LEU E 1 89 ? 32.485 -14.933 68.284 1.00 57.33 ? 89 LEU E CB 1 +ATOM 8317 C CG . LEU E 1 89 ? 32.502 -14.747 69.792 1.00 83.37 ? 89 LEU E CG 1 +ATOM 8318 C CD1 . LEU E 1 89 ? 33.410 -13.612 70.204 1.00 83.79 ? 89 LEU E CD1 1 +ATOM 8319 C CD2 . LEU E 1 89 ? 31.117 -14.521 70.375 1.00 89.10 ? 89 LEU E CD2 1 +ATOM 8320 N N . LEU E 1 90 ? 31.782 -12.838 66.078 1.00 93.52 ? 90 LEU E N 1 +ATOM 8321 C CA . LEU E 1 90 ? 31.779 -11.451 65.589 1.00 87.18 ? 90 LEU E CA 1 +ATOM 8322 C C . LEU E 1 90 ? 30.440 -11.110 64.950 1.00 84.20 ? 90 LEU E C 1 +ATOM 8323 O O . LEU E 1 90 ? 29.984 -9.956 64.975 1.00 75.38 ? 90 LEU E O 1 +ATOM 8324 C CB . LEU E 1 90 ? 32.910 -11.234 64.591 1.00 82.40 ? 90 LEU E CB 1 +ATOM 8325 C CG . LEU E 1 90 ? 34.299 -11.464 65.164 1.00 99.18 ? 90 LEU E CG 1 +ATOM 8326 C CD1 . LEU E 1 90 ? 35.293 -11.698 64.030 1.00 117.96 ? 90 LEU E CD1 1 +ATOM 8327 C CD2 . LEU E 1 90 ? 34.699 -10.279 66.044 1.00 95.80 ? 90 LEU E CD2 1 +ATOM 8328 N N . ASN E 1 91 ? 29.809 -12.130 64.386 1.00 74.18 ? 91 ASN E N 1 +ATOM 8329 C CA . ASN E 1 91 ? 28.534 -11.942 63.768 1.00 80.44 ? 91 ASN E CA 1 +ATOM 8330 C C . ASN E 1 91 ? 27.495 -11.639 64.822 1.00 69.73 ? 91 ASN E C 1 +ATOM 8331 O O . ASN E 1 91 ? 26.647 -10.759 64.634 1.00 93.73 ? 91 ASN E O 1 +ATOM 8332 C CB . ASN E 1 91 ? 28.160 -13.163 62.918 1.00 99.62 ? 91 ASN E CB 1 +ATOM 8333 C CG . ASN E 1 91 ? 27.764 -12.749 61.507 1.00 104.44 ? 91 ASN E CG 1 +ATOM 8334 O OD1 . ASN E 1 91 ? 28.523 -12.021 60.868 1.00 84.44 ? 91 ASN E OD1 1 +ATOM 8335 N ND2 . ASN E 1 91 ? 26.519 -13.048 61.090 1.00 102.05 ? 91 ASN E ND2 1 +ATOM 8336 N N . GLU E 1 92 ? 27.465 -12.454 65.866 1.00 62.84 ? 92 GLU E N 1 +ATOM 8337 C CA . GLU E 1 92 ? 26.460 -12.275 66.913 1.00 73.90 ? 92 GLU E CA 1 +ATOM 8338 C C . GLU E 1 92 ? 26.637 -10.891 67.486 1.00 60.49 ? 92 GLU E C 1 +ATOM 8339 O O . GLU E 1 92 ? 25.644 -10.255 67.897 1.00 116.29 ? 92 GLU E O 1 +ATOM 8340 C CB . GLU E 1 92 ? 26.563 -13.352 68.021 1.00 82.91 ? 92 GLU E CB 1 +ATOM 8341 C CG . GLU E 1 92 ? 25.664 -14.566 67.849 1.00 77.15 ? 92 GLU E CG 1 +ATOM 8342 C CD . GLU E 1 92 ? 24.201 -14.197 67.628 1.00 89.67 ? 92 GLU E CD 1 +ATOM 8343 O OE1 . GLU E 1 92 ? 23.577 -13.534 68.513 1.00 119.71 ? 92 GLU E OE1 1 +ATOM 8344 O OE2 . GLU E 1 92 ? 23.643 -14.635 66.576 1.00 66.08 ? 92 GLU E OE2 1 +ATOM 8345 N N . ARG E 1 93 ? 27.874 -10.446 67.567 1.00 40.08 ? 93 ARG E N 1 +ATOM 8346 C CA . ARG E 1 93 ? 28.127 -9.144 68.119 1.00 57.06 ? 93 ARG E CA 1 +ATOM 8347 C C . ARG E 1 93 ? 27.657 -8.039 67.162 1.00 79.64 ? 93 ARG E C 1 +ATOM 8348 O O . ARG E 1 93 ? 27.154 -6.993 67.592 1.00 78.53 ? 93 ARG E O 1 +ATOM 8349 C CB . ARG E 1 93 ? 29.596 -9.025 68.461 1.00 77.75 ? 93 ARG E CB 1 +ATOM 8350 C CG . ARG E 1 93 ? 29.970 -9.900 69.651 1.00 80.26 ? 93 ARG E CG 1 +ATOM 8351 C CD . ARG E 1 93 ? 31.467 -10.102 69.823 1.00 97.65 ? 93 ARG E CD 1 +ATOM 8352 N NE . ARG E 1 93 ? 32.028 -9.242 70.860 1.00 124.56 ? 93 ARG E NE 1 +ATOM 8353 C CZ . ARG E 1 93 ? 32.616 -8.061 70.648 1.00 123.69 ? 93 ARG E CZ 1 +ATOM 8354 N NH1 . ARG E 1 93 ? 32.768 -7.563 69.426 1.00 93.95 ? 93 ARG E NH1 1 +ATOM 8355 N NH2 . ARG E 1 93 ? 33.113 -7.414 71.686 1.00 157.71 ? 93 ARG E NH2 1 +ATOM 8356 N N . LYS E 1 94 ? 27.703 -8.303 65.855 1.00 108.11 ? 94 LYS E N 1 +ATOM 8357 C CA . LYS E 1 94 ? 27.095 -7.382 64.863 1.00 108.74 ? 94 LYS E CA 1 +ATOM 8358 C C . LYS E 1 94 ? 25.583 -7.309 65.029 1.00 81.16 ? 94 LYS E C 1 +ATOM 8359 O O . LYS E 1 94 ? 25.008 -6.197 65.014 1.00 77.87 ? 94 LYS E O 1 +ATOM 8360 C CB . LYS E 1 94 ? 27.356 -7.837 63.438 1.00 123.68 ? 94 LYS E CB 1 +ATOM 8361 C CG . LYS E 1 94 ? 28.658 -7.354 62.826 1.00 148.08 ? 94 LYS E CG 1 +ATOM 8362 C CD . LYS E 1 94 ? 28.881 -8.047 61.489 1.00 166.57 ? 94 LYS E CD 1 +ATOM 8363 C CE . LYS E 1 94 ? 29.867 -7.313 60.596 1.00 174.77 ? 94 LYS E CE 1 +ATOM 8364 N NZ . LYS E 1 94 ? 30.303 -8.193 59.478 1.00 173.49 ? 94 LYS E NZ 1 +ATOM 8365 N N . ILE E 1 95 ? 24.961 -8.470 65.275 1.00 51.39 ? 95 ILE E N 1 +ATOM 8366 C CA . ILE E 1 95 ? 23.524 -8.508 65.464 1.00 56.80 ? 95 ILE E CA 1 +ATOM 8367 C C . ILE E 1 95 ? 23.069 -7.780 66.739 1.00 67.53 ? 95 ILE E C 1 +ATOM 8368 O O . ILE E 1 95 ? 22.011 -7.083 66.738 1.00 66.61 ? 95 ILE E O 1 +ATOM 8369 C CB . ILE E 1 95 ? 22.940 -9.918 65.481 1.00 47.74 ? 95 ILE E CB 1 +ATOM 8370 C CG1 . ILE E 1 95 ? 23.497 -10.711 64.335 1.00 53.98 ? 95 ILE E CG1 1 +ATOM 8371 C CG2 . ILE E 1 95 ? 21.436 -9.823 65.310 1.00 54.64 ? 95 ILE E CG2 1 +ATOM 8372 C CD1 . ILE E 1 95 ? 22.766 -12.010 64.057 1.00 66.31 ? 95 ILE E CD1 1 +ATOM 8373 N N . ILE E 1 96 ? 23.838 -7.990 67.811 1.00 60.00 ? 96 ILE E N 1 +ATOM 8374 C CA . ILE E 1 96 ? 23.635 -7.289 69.069 1.00 60.95 ? 96 ILE E CA 1 +ATOM 8375 C C . ILE E 1 96 ? 23.684 -5.814 68.838 1.00 54.19 ? 96 ILE E C 1 +ATOM 8376 O O . ILE E 1 96 ? 22.716 -5.106 69.111 1.00 48.68 ? 96 ILE E O 1 +ATOM 8377 C CB . ILE E 1 96 ? 24.690 -7.646 70.117 1.00 82.38 ? 96 ILE E CB 1 +ATOM 8378 C CG1 . ILE E 1 96 ? 24.506 -9.105 70.553 1.00 131.28 ? 96 ILE E CG1 1 +ATOM 8379 C CG2 . ILE E 1 96 ? 24.520 -6.775 71.338 1.00 82.52 ? 96 ILE E CG2 1 +ATOM 8380 C CD1 . ILE E 1 96 ? 25.463 -9.541 71.645 1.00 163.72 ? 96 ILE E CD1 1 +ATOM 8381 N N . ARG E 1 97 ? 24.816 -5.341 68.342 1.00 72.16 ? 97 ARG E N 1 +ATOM 8382 C CA . ARG E 1 97 ? 25.004 -3.899 68.127 1.00 93.09 ? 97 ARG E CA 1 +ATOM 8383 C C . ARG E 1 97 ? 23.923 -3.291 67.211 1.00 83.84 ? 97 ARG E C 1 +ATOM 8384 O O . ARG E 1 97 ? 23.540 -2.118 67.368 1.00 72.56 ? 97 ARG E O 1 +ATOM 8385 C CB . ARG E 1 97 ? 26.395 -3.599 67.547 1.00 102.85 ? 97 ARG E CB 1 +ATOM 8386 C CG . ARG E 1 97 ? 27.402 -3.086 68.554 1.00 101.66 ? 97 ARG E CG 1 +ATOM 8387 C CD . ARG E 1 97 ? 28.728 -2.758 67.887 1.00 104.07 ? 97 ARG E CD 1 +ATOM 8388 N NE . ARG E 1 97 ? 29.551 -3.958 67.688 1.00 96.46 ? 97 ARG E NE 1 +ATOM 8389 C CZ . ARG E 1 97 ? 30.583 -4.317 68.467 1.00 75.93 ? 97 ARG E CZ 1 +ATOM 8390 N NH1 . ARG E 1 97 ? 30.939 -3.600 69.536 1.00 54.22 ? 97 ARG E NH1 1 +ATOM 8391 N NH2 . ARG E 1 97 ? 31.241 -5.424 68.189 1.00 81.01 ? 97 ARG E NH2 1 +ATOM 8392 N N . ALA E 1 98 ? 23.430 -4.086 66.262 1.00 77.01 ? 98 ALA E N 1 +ATOM 8393 C CA . ALA E 1 98 ? 22.378 -3.626 65.372 1.00 92.37 ? 98 ALA E CA 1 +ATOM 8394 C C . ALA E 1 98 ? 21.021 -3.612 66.088 1.00 111.02 ? 98 ALA E C 1 +ATOM 8395 O O . ALA E 1 98 ? 20.155 -2.777 65.769 1.00 97.34 ? 98 ALA E O 1 +ATOM 8396 C CB . ALA E 1 98 ? 22.313 -4.509 64.153 1.00 90.52 ? 98 ALA E CB 1 +ATOM 8397 N N . ALA E 1 99 ? 20.867 -4.499 67.079 1.00 105.10 ? 99 ALA E N 1 +ATOM 8398 C CA . ALA E 1 99 ? 19.648 -4.556 67.894 1.00 89.04 ? 99 ALA E CA 1 +ATOM 8399 C C . ALA E 1 99 ? 19.451 -3.332 68.785 1.00 96.74 ? 99 ALA E C 1 +ATOM 8400 O O . ALA E 1 99 ? 18.387 -2.699 68.790 1.00 146.50 ? 99 ALA E O 1 +ATOM 8401 C CB . ALA E 1 99 ? 19.663 -5.782 68.757 1.00 78.95 ? 99 ALA E CB 1 +ATOM 8402 N N . GLN E 1 100 ? 20.490 -2.979 69.533 1.00 93.24 ? 100 GLN E N 1 +ATOM 8403 C CA . GLN E 1 100 ? 20.346 -2.030 70.643 1.00 101.14 ? 100 GLN E CA 1 +ATOM 8404 C C . GLN E 1 100 ? 20.899 -0.635 70.377 1.00 95.05 ? 100 GLN E C 1 +ATOM 8405 O O . GLN E 1 100 ? 20.926 0.205 71.275 1.00 113.97 ? 100 GLN E O 1 +ATOM 8406 C CB . GLN E 1 100 ? 20.969 -2.610 71.923 1.00 97.39 ? 100 GLN E CB 1 +ATOM 8407 C CG . GLN E 1 100 ? 22.315 -3.286 71.736 1.00 88.42 ? 100 GLN E CG 1 +ATOM 8408 C CD . GLN E 1 100 ? 22.587 -4.393 72.750 1.00 86.78 ? 100 GLN E CD 1 +ATOM 8409 O OE1 . GLN E 1 100 ? 21.840 -5.387 72.867 1.00 67.78 ? 100 GLN E OE1 1 +ATOM 8410 N NE2 . GLN E 1 100 ? 23.674 -4.229 73.483 1.00 99.28 ? 100 GLN E NE2 1 +ATOM 8411 N N . GLU E 1 101 ? 21.302 -0.374 69.143 1.00 93.98 ? 101 GLU E N 1 +ATOM 8412 C CA . GLU E 1 101 ? 21.884 0.923 68.805 1.00 105.60 ? 101 GLU E CA 1 +ATOM 8413 C C . GLU E 1 101 ? 20.869 2.064 68.875 1.00 110.86 ? 101 GLU E C 1 +ATOM 8414 O O . GLU E 1 101 ? 21.251 3.230 69.029 1.00 89.81 ? 101 GLU E O 1 +ATOM 8415 C CB . GLU E 1 101 ? 22.540 0.876 67.417 1.00 119.68 ? 101 GLU E CB 1 +ATOM 8416 C CG . GLU E 1 101 ? 21.649 0.341 66.298 1.00 113.37 ? 101 GLU E CG 1 +ATOM 8417 C CD . GLU E 1 101 ? 22.328 0.389 64.934 1.00 110.94 ? 101 GLU E CD 1 +ATOM 8418 O OE1 . GLU E 1 101 ? 23.569 0.526 64.893 1.00 113.88 ? 101 GLU E OE1 1 +ATOM 8419 O OE2 . GLU E 1 101 ? 21.622 0.313 63.902 1.00 126.11 ? 101 GLU E OE2 1 +ATOM 8420 N N . ASN E 1 102 ? 19.581 1.742 68.728 1.00 115.36 ? 102 ASN E N 1 +ATOM 8421 C CA . ASN E 1 102 ? 18.537 2.771 68.693 1.00 115.55 ? 102 ASN E CA 1 +ATOM 8422 C C . ASN E 1 102 ? 17.939 3.039 70.068 1.00 134.53 ? 102 ASN E C 1 +ATOM 8423 O O . ASN E 1 102 ? 17.097 3.924 70.216 1.00 153.42 ? 102 ASN E O 1 +ATOM 8424 C CB . ASN E 1 102 ? 17.410 2.376 67.741 1.00 108.12 ? 102 ASN E CB 1 +ATOM 8425 C CG . ASN E 1 102 ? 17.801 2.482 66.283 1.00 107.90 ? 102 ASN E CG 1 +ATOM 8426 O OD1 . ASN E 1 102 ? 17.893 3.575 65.721 1.00 71.12 ? 102 ASN E OD1 1 +ATOM 8427 N ND2 . ASN E 1 102 ? 18.147 1.340 65.700 1.00 134.61 ? 102 ASN E ND2 1 +ATOM 8428 N N . GLY E 1 103 ? 18.379 2.297 71.081 1.00 141.85 ? 103 GLY E N 1 +ATOM 8429 C CA . GLY E 1 103 ? 17.884 2.508 72.446 1.00 123.19 ? 103 GLY E CA 1 +ATOM 8430 C C . GLY E 1 103 ? 16.392 2.290 72.584 1.00 107.29 ? 103 GLY E C 1 +ATOM 8431 O O . GLY E 1 103 ? 15.715 2.955 73.364 1.00 98.76 ? 103 GLY E O 1 +ATOM 8432 N N . THR E 1 104 ? 15.868 1.366 71.798 1.00 115.36 ? 104 THR E N 1 +ATOM 8433 C CA . THR E 1 104 ? 14.520 0.907 72.005 1.00 113.02 ? 104 THR E CA 1 +ATOM 8434 C C . THR E 1 104 ? 14.558 -0.410 72.771 1.00 119.01 ? 104 THR E C 1 +ATOM 8435 O O . THR E 1 104 ? 13.614 -0.718 73.487 1.00 119.56 ? 104 THR E O 1 +ATOM 8436 C CB . THR E 1 104 ? 13.736 0.750 70.678 1.00 113.11 ? 104 THR E CB 1 +ATOM 8437 O OG1 . THR E 1 104 ? 14.321 -0.277 69.858 1.00 90.38 ? 104 THR E OG1 1 +ATOM 8438 C CG2 . THR E 1 104 ? 13.708 2.072 69.925 1.00 96.24 ? 104 THR E CG2 1 +ATOM 8439 N N . VAL E 1 105 ? 15.644 -1.177 72.649 1.00 131.52 ? 105 VAL E N 1 +ATOM 8440 C CA . VAL E 1 105 ? 15.656 -2.552 73.181 1.00 149.93 ? 105 VAL E CA 1 +ATOM 8441 C C . VAL E 1 105 ? 15.456 -2.548 74.692 1.00 143.97 ? 105 VAL E C 1 +ATOM 8442 O O . VAL E 1 105 ? 15.962 -1.667 75.399 1.00 131.74 ? 105 VAL E O 1 +ATOM 8443 C CB . VAL E 1 105 ? 16.928 -3.362 72.789 1.00 162.94 ? 105 VAL E CB 1 +ATOM 8444 C CG1 . VAL E 1 105 ? 17.342 -4.334 73.891 1.00 151.87 ? 105 VAL E CG1 1 +ATOM 8445 C CG2 . VAL E 1 105 ? 16.705 -4.135 71.477 1.00 163.89 ? 105 VAL E CG2 1 +ATOM 8446 N N . ALA E 1 106 ? 14.656 -3.515 75.153 1.00 146.80 ? 106 ALA E N 1 +ATOM 8447 C CA . ALA E 1 106 ? 14.183 -3.577 76.531 1.00 147.56 ? 106 ALA E CA 1 +ATOM 8448 C C . ALA E 1 106 ? 15.348 -3.736 77.500 1.00 152.61 ? 106 ALA E C 1 +ATOM 8449 O O . ALA E 1 106 ? 16.246 -4.545 77.271 1.00 181.40 ? 106 ALA E O 1 +ATOM 8450 C CB . ALA E 1 106 ? 13.202 -4.730 76.690 1.00 144.92 ? 106 ALA E CB 1 +ATOM 8451 N N . ILE E 1 107 ? 15.328 -2.950 78.575 1.00 139.53 ? 107 ILE E N 1 +ATOM 8452 C CA . ILE E 1 107 ? 16.452 -2.871 79.516 1.00 129.63 ? 107 ILE E CA 1 +ATOM 8453 C C . ILE E 1 107 ? 16.802 -4.238 80.147 1.00 111.96 ? 107 ILE E C 1 +ATOM 8454 O O . ILE E 1 107 ? 17.956 -4.517 80.469 1.00 74.13 ? 107 ILE E O 1 +ATOM 8455 C CB . ILE E 1 107 ? 16.166 -1.813 80.616 1.00 121.95 ? 107 ILE E CB 1 +ATOM 8456 C CG1 . ILE E 1 107 ? 17.435 -1.500 81.427 1.00 108.11 ? 107 ILE E CG1 1 +ATOM 8457 C CG2 . ILE E 1 107 ? 15.038 -2.282 81.532 1.00 119.14 ? 107 ILE E CG2 1 +ATOM 8458 C CD1 . ILE E 1 107 ? 18.608 -1.003 80.609 1.00 99.01 ? 107 ILE E CD1 1 +ATOM 8459 N N . ASN E 1 108 ? 15.794 -5.086 80.302 1.00 136.40 ? 108 ASN E N 1 +ATOM 8460 C CA . ASN E 1 108 ? 15.997 -6.455 80.791 1.00 160.10 ? 108 ASN E CA 1 +ATOM 8461 C C . ASN E 1 108 ? 16.717 -7.307 79.750 1.00 148.20 ? 108 ASN E C 1 +ATOM 8462 O O . ASN E 1 108 ? 17.483 -8.202 80.081 1.00 141.67 ? 108 ASN E O 1 +ATOM 8463 C CB . ASN E 1 108 ? 14.646 -7.106 81.130 1.00 171.14 ? 108 ASN E CB 1 +ATOM 8464 C CG . ASN E 1 108 ? 13.608 -6.096 81.593 1.00 175.56 ? 108 ASN E CG 1 +ATOM 8465 O OD1 . ASN E 1 108 ? 13.532 -5.771 82.779 1.00 215.01 ? 108 ASN E OD1 1 +ATOM 8466 N ND2 . ASN E 1 108 ? 12.798 -5.598 80.658 1.00 146.45 ? 108 ASN E ND2 1 +ATOM 8467 N N . ASN E 1 109 ? 16.397 -7.052 78.490 1.00 130.99 ? 109 ASN E N 1 +ATOM 8468 C CA . ASN E 1 109 ? 16.869 -7.862 77.385 1.00 120.09 ? 109 ASN E CA 1 +ATOM 8469 C C . ASN E 1 109 ? 18.237 -7.419 76.882 1.00 127.58 ? 109 ASN E C 1 +ATOM 8470 O O . ASN E 1 109 ? 18.903 -8.156 76.149 1.00 146.49 ? 109 ASN E O 1 +ATOM 8471 C CB . ASN E 1 109 ? 15.846 -7.821 76.243 1.00 114.79 ? 109 ASN E CB 1 +ATOM 8472 C CG . ASN E 1 109 ? 15.259 -9.185 75.952 1.00 123.34 ? 109 ASN E CG 1 +ATOM 8473 O OD1 . ASN E 1 109 ? 15.470 -9.751 74.878 1.00 130.78 ? 109 ASN E OD1 1 +ATOM 8474 N ND2 . ASN E 1 109 ? 14.543 -9.737 76.922 1.00 140.31 ? 109 ASN E ND2 1 +ATOM 8475 N N . ARG E 1 110 ? 18.627 -6.198 77.253 1.00 114.93 ? 110 ARG E N 1 +ATOM 8476 C CA . ARG E 1 110 ? 19.839 -5.538 76.731 1.00 100.87 ? 110 ARG E CA 1 +ATOM 8477 C C . ARG E 1 110 ? 21.083 -6.386 76.977 1.00 107.00 ? 110 ARG E C 1 +ATOM 8478 O O . ARG E 1 110 ? 21.253 -6.939 78.074 1.00 156.81 ? 110 ARG E O 1 +ATOM 8479 C CB . ARG E 1 110 ? 20.013 -4.184 77.426 1.00 95.39 ? 110 ARG E CB 1 +ATOM 8480 C CG . ARG E 1 110 ? 20.853 -3.180 76.672 1.00 104.35 ? 110 ARG E CG 1 +ATOM 8481 C CD . ARG E 1 110 ? 20.367 -1.759 76.885 1.00 115.69 ? 110 ARG E CD 1 +ATOM 8482 N NE . ARG E 1 110 ? 21.017 -1.141 78.049 1.00 131.92 ? 110 ARG E NE 1 +ATOM 8483 C CZ . ARG E 1 110 ? 21.757 -0.024 78.020 1.00 133.42 ? 110 ARG E CZ 1 +ATOM 8484 N NH1 . ARG E 1 110 ? 21.969 0.645 76.879 1.00 105.27 ? 110 ARG E NH1 1 +ATOM 8485 N NH2 . ARG E 1 110 ? 22.263 0.451 79.158 1.00 129.85 ? 110 ARG E NH2 1 +ATOM 8486 N N . ILE E 1 111 ? 21.940 -6.520 75.967 1.00 83.71 ? 111 ILE E N 1 +ATOM 8487 C CA . ILE E 1 111 ? 23.201 -7.230 76.153 1.00 78.39 ? 111 ILE E CA 1 +ATOM 8488 C C . ILE E 1 111 ? 24.342 -6.254 76.141 1.00 84.62 ? 111 ILE E C 1 +ATOM 8489 O O . ILE E 1 111 ? 24.585 -5.642 75.117 1.00 88.69 ? 111 ILE E O 1 +ATOM 8490 C CB . ILE E 1 111 ? 23.445 -8.280 75.069 1.00 79.82 ? 111 ILE E CB 1 +ATOM 8491 C CG1 . ILE E 1 111 ? 22.373 -9.373 75.164 1.00 106.34 ? 111 ILE E CG1 1 +ATOM 8492 C CG2 . ILE E 1 111 ? 24.830 -8.904 75.236 1.00 76.45 ? 111 ILE E CG2 1 +ATOM 8493 C CD1 . ILE E 1 111 ? 22.323 -10.318 73.975 1.00 113.95 ? 111 ILE E CD1 1 +ATOM 8494 N N . PRO E 1 112 ? 25.082 -6.143 77.265 1.00 108.13 ? 112 PRO E N 1 +ATOM 8495 C CA . PRO E 1 112 ? 26.176 -5.191 77.332 1.00 106.86 ? 112 PRO E CA 1 +ATOM 8496 C C . PRO E 1 112 ? 27.426 -5.756 76.661 1.00 129.63 ? 112 PRO E C 1 +ATOM 8497 O O . PRO E 1 112 ? 27.831 -6.898 76.940 1.00 98.84 ? 112 PRO E O 1 +ATOM 8498 C CB . PRO E 1 112 ? 26.398 -5.026 78.832 1.00 110.73 ? 112 PRO E CB 1 +ATOM 8499 C CG . PRO E 1 112 ? 26.037 -6.359 79.402 1.00 114.41 ? 112 PRO E CG 1 +ATOM 8500 C CD . PRO E 1 112 ? 25.016 -6.978 78.481 1.00 118.03 ? 112 PRO E CD 1 +ATOM 8501 N N . LEU E 1 113 ? 28.006 -4.968 75.756 1.00 137.97 ? 113 LEU E N 1 +ATOM 8502 C CA . LEU E 1 113 ? 29.112 -5.433 74.926 1.00 98.22 ? 113 LEU E CA 1 +ATOM 8503 C C . LEU E 1 113 ? 30.423 -4.827 75.358 1.00 82.71 ? 113 LEU E C 1 +ATOM 8504 O O . LEU E 1 113 ? 30.524 -3.632 75.693 1.00 61.47 ? 113 LEU E O 1 +ATOM 8505 C CB . LEU E 1 113 ? 28.856 -5.138 73.458 1.00 87.62 ? 113 LEU E CB 1 +ATOM 8506 C CG . LEU E 1 113 ? 28.049 -6.199 72.712 1.00 92.01 ? 113 LEU E CG 1 +ATOM 8507 C CD1 . LEU E 1 113 ? 27.966 -5.796 71.253 1.00 92.29 ? 113 LEU E CD1 1 +ATOM 8508 C CD2 . LEU E 1 113 ? 28.668 -7.585 72.852 1.00 101.67 ? 113 LEU E CD2 1 +ATOM 8509 N N . GLN E 1 114 ? 31.430 -5.684 75.334 1.00 70.84 ? 114 GLN E N 1 +ATOM 8510 C CA . GLN E 1 114 ? 32.725 -5.370 75.899 1.00 81.55 ? 114 GLN E CA 1 +ATOM 8511 C C . GLN E 1 114 ? 33.720 -5.903 74.918 1.00 94.30 ? 114 GLN E C 1 +ATOM 8512 O O . GLN E 1 114 ? 33.403 -6.852 74.186 1.00 154.05 ? 114 GLN E O 1 +ATOM 8513 C CB . GLN E 1 114 ? 32.896 -6.084 77.219 1.00 78.83 ? 114 GLN E CB 1 +ATOM 8514 C CG . GLN E 1 114 ? 33.803 -5.376 78.204 1.00 75.44 ? 114 GLN E CG 1 +ATOM 8515 C CD . GLN E 1 114 ? 34.476 -6.347 79.158 1.00 67.24 ? 114 GLN E CD 1 +ATOM 8516 O OE1 . GLN E 1 114 ? 35.550 -6.061 79.698 1.00 60.16 ? 114 GLN E OE1 1 +ATOM 8517 N NE2 . GLN E 1 114 ? 33.812 -7.480 79.415 1.00 64.05 ? 114 GLN E NE2 1 +ATOM 8518 N N . SER E 1 115 ? 34.855 -5.222 74.791 1.00 73.95 ? 115 SER E N 1 +ATOM 8519 C CA . SER E 1 115 ? 35.814 -5.564 73.755 1.00 78.50 ? 115 SER E CA 1 +ATOM 8520 C C . SER E 1 115 ? 36.193 -7.024 73.927 1.00 87.07 ? 115 SER E C 1 +ATOM 8521 O O . SER E 1 115 ? 36.105 -7.564 75.065 1.00 116.45 ? 115 SER E O 1 +ATOM 8522 C CB . SER E 1 115 ? 37.033 -4.651 73.848 1.00 78.33 ? 115 SER E CB 1 +ATOM 8523 O OG . SER E 1 115 ? 37.528 -4.577 75.175 1.00 88.43 ? 115 SER E OG 1 +ATOM 8524 N N . LEU E 1 116 ? 36.611 -7.683 72.840 1.00 66.43 ? 116 LEU E N 1 +ATOM 8525 C CA . LEU E 1 116 ? 36.841 -9.117 72.966 1.00 74.27 ? 116 LEU E CA 1 +ATOM 8526 C C . LEU E 1 116 ? 38.048 -9.348 73.880 1.00 85.20 ? 116 LEU E C 1 +ATOM 8527 O O . LEU E 1 116 ? 39.114 -8.782 73.636 1.00 88.60 ? 116 LEU E O 1 +ATOM 8528 C CB . LEU E 1 116 ? 37.078 -9.775 71.632 1.00 71.67 ? 116 LEU E CB 1 +ATOM 8529 C CG . LEU E 1 116 ? 35.907 -9.710 70.682 1.00 99.58 ? 116 LEU E CG 1 +ATOM 8530 C CD1 . LEU E 1 116 ? 36.001 -8.510 69.734 1.00 115.58 ? 116 LEU E CD1 1 +ATOM 8531 C CD2 . LEU E 1 116 ? 35.879 -11.021 69.907 1.00 130.25 ? 116 LEU E CD2 1 +ATOM 8532 N N . THR E 1 117 ? 37.858 -10.124 74.946 1.00 86.88 ? 117 THR E N 1 +ATOM 8533 C CA . THR E 1 117 ? 38.936 -10.469 75.849 1.00 108.76 ? 117 THR E CA 1 +ATOM 8534 C C . THR E 1 117 ? 40.077 -11.102 75.059 1.00 115.40 ? 117 THR E C 1 +ATOM 8535 O O . THR E 1 117 ? 39.834 -11.968 74.217 1.00 117.96 ? 117 THR E O 1 +ATOM 8536 C CB . THR E 1 117 ? 38.487 -11.494 76.908 1.00 134.39 ? 117 THR E CB 1 +ATOM 8537 O OG1 . THR E 1 117 ? 37.331 -10.998 77.595 1.00 169.95 ? 117 THR E OG1 1 +ATOM 8538 C CG2 . THR E 1 117 ? 39.592 -11.714 77.924 1.00 135.28 ? 117 THR E CG2 1 +ATOM 8539 N N . ALA E 1 118 ? 41.308 -10.662 75.332 1.00 104.49 ? 118 ALA E N 1 +ATOM 8540 C CA . ALA E 1 118 ? 42.449 -10.958 74.459 1.00 86.84 ? 118 ALA E CA 1 +ATOM 8541 C C . ALA E 1 118 ? 43.471 -11.716 75.177 1.00 82.35 ? 118 ALA E C 1 +ATOM 8542 O O . ALA E 1 118 ? 43.779 -11.423 76.353 1.00 82.14 ? 118 ALA E O 1 +ATOM 8543 C CB . ALA E 1 118 ? 43.073 -9.684 73.924 1.00 119.73 ? 118 ALA E CB 1 +ATOM 8544 N N . ALA E 1 119 ? 44.025 -12.687 74.467 1.00 97.73 ? 119 ALA E N 1 +ATOM 8545 C CA . ALA E 1 119 ? 44.953 -13.658 75.058 1.00 107.61 ? 119 ALA E CA 1 +ATOM 8546 C C . ALA E 1 119 ? 46.400 -13.150 75.055 1.00 93.84 ? 119 ALA E C 1 +ATOM 8547 O O . ALA E 1 119 ? 46.749 -12.289 74.243 1.00 63.12 ? 119 ALA E O 1 +ATOM 8548 C CB . ALA E 1 119 ? 44.879 -14.956 74.300 1.00 94.62 ? 119 ALA E CB 1 +ATOM 8549 N N . ASN E 1 120 ? 47.212 -13.637 75.998 1.00 79.90 ? 120 ASN E N 1 +ATOM 8550 C CA . ASN E 1 120 ? 48.624 -13.278 76.016 1.00 89.43 ? 120 ASN E CA 1 +ATOM 8551 C C . ASN E 1 120 ? 49.509 -14.325 75.371 1.00 84.81 ? 120 ASN E C 1 +ATOM 8552 O O . ASN E 1 120 ? 50.400 -14.019 74.586 1.00 96.79 ? 120 ASN E O 1 +ATOM 8553 C CB . ASN E 1 120 ? 49.146 -13.021 77.423 1.00 93.72 ? 120 ASN E CB 1 +ATOM 8554 C CG . ASN E 1 120 ? 50.603 -12.554 77.412 1.00 118.61 ? 120 ASN E CG 1 +ATOM 8555 O OD1 . ASN E 1 120 ? 51.392 -12.998 78.237 1.00 145.81 ? 120 ASN E OD1 1 +ATOM 8556 N ND2 . ASN E 1 120 ? 50.986 -11.710 76.421 1.00 113.03 ? 120 ASN E ND2 1 +ATOM 8557 N N . ILE E 1 121 ? 49.303 -15.566 75.752 1.00 69.76 ? 121 ILE E N 1 +ATOM 8558 C CA . ILE E 1 121 ? 49.946 -16.638 75.058 1.00 76.82 ? 121 ILE E CA 1 +ATOM 8559 C C . ILE E 1 121 ? 48.890 -17.360 74.232 1.00 83.65 ? 121 ILE E C 1 +ATOM 8560 O O . ILE E 1 121 ? 47.761 -17.548 74.644 1.00 94.07 ? 121 ILE E O 1 +ATOM 8561 C CB . ILE E 1 121 ? 50.664 -17.597 76.032 1.00 97.37 ? 121 ILE E CB 1 +ATOM 8562 C CG1 . ILE E 1 121 ? 49.675 -18.493 76.809 1.00 124.49 ? 121 ILE E CG1 1 +ATOM 8563 C CG2 . ILE E 1 121 ? 51.558 -16.815 76.988 1.00 93.13 ? 121 ILE E CG2 1 +ATOM 8564 C CD1 . ILE E 1 121 ? 49.725 -19.959 76.414 1.00 134.49 ? 121 ILE E CD1 1 +ATOM 8565 N N . MET E 1 122 ? 49.270 -17.781 73.056 1.00 91.11 ? 122 MET E N 1 +ATOM 8566 C CA . MET E 1 122 ? 48.468 -18.732 72.387 1.00 103.72 ? 122 MET E CA 1 +ATOM 8567 C C . MET E 1 122 ? 49.273 -20.024 72.211 1.00 86.42 ? 122 MET E C 1 +ATOM 8568 O O . MET E 1 122 ? 50.455 -19.989 71.891 1.00 83.20 ? 122 MET E O 1 +ATOM 8569 C CB . MET E 1 122 ? 47.935 -18.104 71.076 1.00 150.70 ? 122 MET E CB 1 +ATOM 8570 C CG . MET E 1 122 ? 48.966 -17.579 70.080 1.00 132.10 ? 122 MET E CG 1 +ATOM 8571 S SD . MET E 1 122 ? 48.310 -17.706 68.386 1.00 98.91 ? 122 MET E SD 1 +ATOM 8572 C CE . MET E 1 122 ? 49.722 -18.244 67.476 1.00 90.58 ? 122 MET E CE 1 +ATOM 8573 N N . VAL E 1 123 ? 48.589 -21.157 72.299 1.00 59.75 ? 123 VAL E N 1 +ATOM 8574 C CA . VAL E 1 123 ? 49.216 -22.434 72.004 1.00 53.69 ? 123 VAL E CA 1 +ATOM 8575 C C . VAL E 1 123 ? 48.645 -23.165 70.804 1.00 49.84 ? 123 VAL E C 1 +ATOM 8576 O O . VAL E 1 123 ? 47.433 -23.311 70.654 1.00 50.76 ? 123 VAL E O 1 +ATOM 8577 C CB . VAL E 1 123 ? 49.066 -23.351 73.189 1.00 70.19 ? 123 VAL E CB 1 +ATOM 8578 C CG1 . VAL E 1 123 ? 47.670 -23.235 73.795 1.00 65.36 ? 123 VAL E CG1 1 +ATOM 8579 C CG2 . VAL E 1 123 ? 49.404 -24.805 72.819 1.00 85.34 ? 123 VAL E CG2 1 +ATOM 8580 N N . GLU E 1 124 ? 49.520 -23.588 69.904 1.00 70.44 ? 124 GLU E N 1 +ATOM 8581 C CA . GLU E 1 124 ? 49.099 -24.354 68.730 1.00 108.42 ? 124 GLU E CA 1 +ATOM 8582 C C . GLU E 1 124 ? 49.980 -25.566 68.591 1.00 108.49 ? 124 GLU E C 1 +ATOM 8583 O O . GLU E 1 124 ? 50.976 -25.698 69.267 1.00 64.64 ? 124 GLU E O 1 +ATOM 8584 C CB . GLU E 1 124 ? 49.142 -23.545 67.414 1.00 135.84 ? 124 GLU E CB 1 +ATOM 8585 C CG . GLU E 1 124 ? 50.183 -22.440 67.342 1.00 137.51 ? 124 GLU E CG 1 +ATOM 8586 C CD . GLU E 1 124 ? 49.878 -21.432 66.248 1.00 154.41 ? 124 GLU E CD 1 +ATOM 8587 O OE1 . GLU E 1 124 ? 48.687 -21.157 65.986 1.00 122.89 ? 124 GLU E OE1 1 +ATOM 8588 O OE2 . GLU E 1 124 ? 50.844 -20.985 65.604 1.00 203.97 ? 124 GLU E OE2 1 +ATOM 8589 N N . GLY E 1 125 ? 49.564 -26.475 67.719 1.00 139.19 ? 125 GLY E N 1 +ATOM 8590 C CA . GLY E 1 125 ? 50.238 -27.751 67.573 1.00 111.02 ? 125 GLY E CA 1 +ATOM 8591 C C . GLY E 1 125 ? 49.703 -28.554 66.407 1.00 76.08 ? 125 GLY E C 1 +ATOM 8592 O O . GLY E 1 125 ? 49.045 -28.014 65.518 1.00 63.07 ? 125 GLY E O 1 +ATOM 8593 N N . SER E 1 126 ? 49.981 -29.844 66.420 1.00 59.05 ? 126 SER E N 1 +ATOM 8594 C CA . SER E 1 126 ? 49.650 -30.663 65.285 1.00 71.19 ? 126 SER E CA 1 +ATOM 8595 C C . SER E 1 126 ? 49.651 -32.105 65.690 1.00 96.14 ? 126 SER E C 1 +ATOM 8596 O O . SER E 1 126 ? 50.395 -32.499 66.598 1.00 123.90 ? 126 SER E O 1 +ATOM 8597 C CB . SER E 1 126 ? 50.677 -30.503 64.161 1.00 66.93 ? 126 SER E CB 1 +ATOM 8598 O OG . SER E 1 126 ? 51.238 -29.202 64.121 1.00 57.95 ? 126 SER E OG 1 +ATOM 8599 N N . ILE E 1 127 ? 48.795 -32.905 65.051 1.00 88.70 ? 127 ILE E N 1 +ATOM 8600 C CA . ILE E 1 127 ? 48.900 -34.343 65.201 1.00 91.00 ? 127 ILE E CA 1 +ATOM 8601 C C . ILE E 1 127 ? 50.016 -34.743 64.270 1.00 98.57 ? 127 ILE E C 1 +ATOM 8602 O O . ILE E 1 127 ? 49.816 -34.829 63.075 1.00 93.91 ? 127 ILE E O 1 +ATOM 8603 C CB . ILE E 1 127 ? 47.590 -35.109 64.895 1.00 66.73 ? 127 ILE E CB 1 +ATOM 8604 C CG1 . ILE E 1 127 ? 46.536 -34.816 65.990 1.00 55.26 ? 127 ILE E CG1 1 +ATOM 8605 C CG2 . ILE E 1 127 ? 47.850 -36.608 64.849 1.00 66.66 ? 127 ILE E CG2 1 +ATOM 8606 C CD1 . ILE E 1 127 ? 45.123 -34.881 65.474 1.00 59.69 ? 127 ILE E CD1 1 +ATOM 8607 N N . ILE E 1 128 ? 51.190 -35.003 64.852 1.00 97.99 ? 128 ILE E N 1 +ATOM 8608 C CA . ILE E 1 128 ? 52.388 -35.406 64.110 1.00 115.76 ? 128 ILE E CA 1 +ATOM 8609 C C . ILE E 1 128 ? 52.469 -36.926 64.102 1.00 91.51 ? 128 ILE E C 1 +ATOM 8610 O O . ILE E 1 128 ? 52.646 -37.580 65.147 1.00 170.24 ? 128 ILE E O 1 +ATOM 8611 C CB . ILE E 1 128 ? 53.653 -34.785 64.738 1.00 169.87 ? 128 ILE E CB 1 +ATOM 8612 C CG1 . ILE E 1 128 ? 53.744 -35.112 66.231 1.00 211.05 ? 128 ILE E CG1 1 +ATOM 8613 C CG2 . ILE E 1 128 ? 53.598 -33.270 64.642 1.00 183.85 ? 128 ILE E CG2 1 +ATOM 8614 C CD1 . ILE E 1 128 ? 55.168 -35.078 66.759 1.00 239.91 ? 128 ILE E CD1 1 +ATOM 8615 N N . GLY E 1 129 ? 51.995 -37.490 63.009 1.00 93.63 ? 129 GLY E N 1 +ATOM 8616 C CA . GLY E 1 129 ? 52.088 -38.929 62.838 1.00 135.18 ? 129 GLY E CA 1 +ATOM 8617 C C . GLY E 1 129 ? 51.051 -39.885 63.466 1.00 142.09 ? 129 GLY E C 1 +ATOM 8618 O O . GLY E 1 129 ? 50.640 -39.770 64.633 1.00 117.49 ? 129 GLY E O 1 +ATOM 8619 N N . TYR E 1 130 ? 50.648 -40.855 62.654 1.00 123.26 ? 130 TYR E N 1 +ATOM 8620 C CA . TYR E 1 130 ? 50.000 -42.059 63.125 1.00 106.79 ? 130 TYR E CA 1 +ATOM 8621 C C . TYR E 1 130 ? 50.611 -43.177 62.294 1.00 97.70 ? 130 TYR E C 1 +ATOM 8622 O O . TYR E 1 130 ? 50.345 -43.263 61.103 1.00 114.90 ? 130 TYR E O 1 +ATOM 8623 C CB . TYR E 1 130 ? 48.480 -41.951 62.912 1.00 97.15 ? 130 TYR E CB 1 +ATOM 8624 C CG . TYR E 1 130 ? 47.669 -43.188 63.227 1.00 95.76 ? 130 TYR E CG 1 +ATOM 8625 C CD1 . TYR E 1 130 ? 47.759 -44.330 62.429 1.00 87.26 ? 130 TYR E CD1 1 +ATOM 8626 C CD2 . TYR E 1 130 ? 46.744 -43.187 64.279 1.00 105.06 ? 130 TYR E CD2 1 +ATOM 8627 C CE1 . TYR E 1 130 ? 46.994 -45.455 62.708 1.00 110.13 ? 130 TYR E CE1 1 +ATOM 8628 C CE2 . TYR E 1 130 ? 45.956 -44.300 64.557 1.00 131.44 ? 130 TYR E CE2 1 +ATOM 8629 C CZ . TYR E 1 130 ? 46.081 -45.432 63.769 1.00 131.80 ? 130 TYR E CZ 1 +ATOM 8630 O OH . TYR E 1 130 ? 45.368 -46.558 64.123 1.00 110.03 ? 130 TYR E OH 1 +ATOM 8631 N N . GLU E 1 131 ? 51.466 -43.978 62.900 1.00 76.90 ? 131 GLU E N 1 +ATOM 8632 C CA . GLU E 1 131 ? 51.913 -45.194 62.243 1.00 93.26 ? 131 GLU E CA 1 +ATOM 8633 C C . GLU E 1 131 ? 51.031 -46.354 62.724 1.00 115.16 ? 131 GLU E C 1 +ATOM 8634 O O . GLU E 1 131 ? 50.539 -46.355 63.859 1.00 64.15 ? 131 GLU E O 1 +ATOM 8635 C CB . GLU E 1 131 ? 53.418 -45.456 62.425 1.00 133.74 ? 131 GLU E CB 1 +ATOM 8636 C CG . GLU E 1 131 ? 54.279 -44.664 61.385 1.00 155.65 ? 131 GLU E CG 1 +ATOM 8637 C CD . GLU E 1 131 ? 53.672 -44.449 60.044 1.00 150.84 ? 131 GLU E CD 1 +ATOM 8638 O OE1 . GLU E 1 131 ? 53.935 -45.302 59.235 1.00 168.28 ? 131 GLU E OE1 1 +ATOM 8639 O OE2 . GLU E 1 131 ? 53.222 -43.328 59.726 1.00 140.77 ? 131 GLU E OE2 1 +ATOM 8640 N N . SER E 1 132 ? 50.786 -47.318 61.831 1.00 149.33 ? 132 SER E N 1 +ATOM 8641 C CA . SER E 1 132 ? 49.835 -48.398 62.109 1.00 138.13 ? 132 SER E CA 1 +ATOM 8642 C C . SER E 1 132 ? 50.511 -49.783 62.123 1.00 132.51 ? 132 SER E C 1 +ATOM 8643 O O . SER E 1 132 ? 51.384 -50.065 61.295 1.00 106.49 ? 132 SER E O 1 +ATOM 8644 C CB . SER E 1 132 ? 48.699 -48.366 61.093 1.00 123.04 ? 132 SER E CB 1 +ATOM 8645 O OG . SER E 1 132 ? 48.737 -49.506 60.252 1.00 165.17 ? 132 SER E OG 1 +ATOM 8646 N N . ASN E 1 133 ? 50.081 -50.633 63.060 1.00 111.67 ? 133 ASN E N 1 +ATOM 8647 C CA . ASN E 1 133 ? 50.736 -51.916 63.337 1.00 96.90 ? 133 ASN E CA 1 +ATOM 8648 C C . ASN E 1 133 ? 52.223 -51.748 63.515 1.00 116.17 ? 133 ASN E C 1 +ATOM 8649 O O . ASN E 1 133 ? 53.033 -52.342 62.776 1.00 131.04 ? 133 ASN E O 1 +ATOM 8650 C CB . ASN E 1 133 ? 50.465 -52.941 62.230 1.00 89.39 ? 133 ASN E CB 1 +ATOM 8651 C CG . ASN E 1 133 ? 49.001 -53.278 62.091 1.00 95.63 ? 133 ASN E CG 1 +ATOM 8652 O OD1 . ASN E 1 133 ? 48.207 -53.159 63.043 1.00 90.66 ? 133 ASN E OD1 1 +ATOM 8653 N ND2 . ASN E 1 133 ? 48.608 -53.634 60.877 1.00 121.76 ? 133 ASN E ND2 1 +ATOM 8654 N N . VAL E 1 134 ? 52.580 -50.882 64.456 1.00 115.99 ? 134 VAL E N 1 +ATOM 8655 C CA . VAL E 1 134 ? 53.982 -50.577 64.721 1.00 143.65 ? 134 VAL E CA 1 +ATOM 8656 C C . VAL E 1 134 ? 54.584 -51.835 65.316 1.00 142.43 ? 134 VAL E C 1 +ATOM 8657 O O . VAL E 1 134 ? 55.750 -52.172 65.080 1.00 83.34 ? 134 VAL E O 1 +ATOM 8658 C CB . VAL E 1 134 ? 54.113 -49.369 65.678 1.00 138.58 ? 134 VAL E CB 1 +ATOM 8659 C CG1 . VAL E 1 134 ? 55.578 -49.019 65.919 1.00 135.29 ? 134 VAL E CG1 1 +ATOM 8660 C CG2 . VAL E 1 134 ? 53.387 -48.152 65.101 1.00 185.21 ? 134 VAL E CG2 1 +ATOM 8661 N N . LYS E 1 135 ? 53.752 -52.541 66.080 1.00 178.10 ? 135 LYS E N 1 +ATOM 8662 C CA . LYS E 1 135 ? 54.057 -53.915 66.468 1.00 182.29 ? 135 LYS E CA 1 +ATOM 8663 C C . LYS E 1 135 ? 52.824 -54.803 66.345 1.00 153.76 ? 135 LYS E C 1 +ATOM 8664 O O . LYS E 1 135 ? 51.683 -54.332 66.380 1.00 91.76 ? 135 LYS E O 1 +ATOM 8665 C CB . LYS E 1 135 ? 54.582 -53.975 67.908 1.00 219.55 ? 135 LYS E CB 1 +ATOM 8666 C CG . LYS E 1 135 ? 55.891 -53.228 68.125 1.00 227.92 ? 135 LYS E CG 1 +ATOM 8667 C CD . LYS E 1 135 ? 56.283 -53.241 69.594 1.00 211.05 ? 135 LYS E CD 1 +ATOM 8668 C CE . LYS E 1 135 ? 57.570 -52.483 69.838 1.00 191.46 ? 135 LYS E CE 1 +ATOM 8669 N NZ . LYS E 1 135 ? 58.182 -52.911 71.118 1.00 194.18 ? 135 LYS E NZ 1 +ATOM 8670 N N . SER E 1 136 ? 53.076 -56.101 66.244 1.00 162.00 ? 136 SER E N 1 +ATOM 8671 C CA . SER E 1 136 ? 52.008 -57.072 66.137 1.00 140.40 ? 136 SER E CA 1 +ATOM 8672 C C . SER E 1 136 ? 52.518 -58.476 66.411 1.00 145.34 ? 136 SER E C 1 +ATOM 8673 O O . SER E 1 136 ? 53.713 -58.758 66.309 1.00 91.55 ? 136 SER E O 1 +ATOM 8674 C CB . SER E 1 136 ? 51.361 -57.015 64.759 1.00 131.86 ? 136 SER E CB 1 +ATOM 8675 O OG . SER E 1 136 ? 51.396 -58.276 64.122 1.00 147.72 ? 136 SER E OG 1 +ATOM 8676 N N . GLY E 1 137 ? 51.597 -59.350 66.798 1.00 181.36 ? 137 GLY E N 1 +ATOM 8677 C CA . GLY E 1 137 ? 51.938 -60.743 67.072 1.00 197.57 ? 137 GLY E CA 1 +ATOM 8678 C C . GLY E 1 137 ? 50.721 -61.648 67.156 1.00 175.92 ? 137 GLY E C 1 +ATOM 8679 O O . GLY E 1 137 ? 49.589 -61.179 67.182 1.00 91.06 ? 137 GLY E O 1 +ATOM 8680 N N . GLY E 1 138 ? 50.970 -62.949 67.251 1.00 176.03 ? 138 GLY E N 1 +ATOM 8681 C CA . GLY E 1 138 ? 49.899 -63.908 67.437 1.00 172.64 ? 138 GLY E CA 1 +ATOM 8682 C C . GLY E 1 138 ? 50.394 -65.256 67.911 1.00 176.00 ? 138 GLY E C 1 +ATOM 8683 O O . GLY E 1 138 ? 51.495 -65.684 67.562 1.00 158.61 ? 138 GLY E O 1 +ATOM 8684 N N . VAL E 1 139 ? 49.587 -65.909 68.743 1.00 187.34 ? 139 VAL E N 1 +ATOM 8685 C CA . VAL E 1 139 ? 49.882 -67.261 69.216 1.00 168.50 ? 139 VAL E CA 1 +ATOM 8686 C C . VAL E 1 139 ? 48.614 -68.116 69.196 1.00 189.01 ? 139 VAL E C 1 +ATOM 8687 O O . VAL E 1 139 ? 47.587 -67.744 69.773 1.00 201.50 ? 139 VAL E O 1 +ATOM 8688 C CB . VAL E 1 139 ? 50.446 -67.257 70.644 1.00 134.97 ? 139 VAL E CB 1 +ATOM 8689 C CG1 . VAL E 1 139 ? 50.619 -68.682 71.134 1.00 132.60 ? 139 VAL E CG1 1 +ATOM 8690 C CG2 . VAL E 1 139 ? 51.770 -66.505 70.699 1.00 118.90 ? 139 VAL E CG2 1 +ATOM 8691 N N . GLY E 1 140 ? 48.688 -69.262 68.523 1.00 184.99 ? 140 GLY E N 1 +ATOM 8692 C CA . GLY E 1 140 ? 47.534 -70.147 68.387 1.00 167.42 ? 140 GLY E CA 1 +ATOM 8693 C C . GLY E 1 140 ? 47.923 -71.612 68.263 1.00 159.77 ? 140 GLY E C 1 +ATOM 8694 O O . GLY E 1 140 ? 48.938 -71.959 67.653 1.00 134.22 ? 140 GLY E O 1 +ATOM 8695 N N . ALA E 1 141 ? 47.102 -72.479 68.843 1.00 171.76 ? 141 ALA E N 1 +ATOM 8696 C CA . ALA E 1 141 ? 47.327 -73.916 68.751 1.00 169.69 ? 141 ALA E CA 1 +ATOM 8697 C C . ALA E 1 141 ? 46.015 -74.684 68.641 1.00 189.77 ? 141 ALA E C 1 +ATOM 8698 O O . ALA E 1 141 ? 45.006 -74.336 69.266 1.00 157.44 ? 141 ALA E O 1 +ATOM 8699 C CB . ALA E 1 141 ? 48.135 -74.406 69.939 1.00 153.39 ? 141 ALA E CB 1 +ATOM 8700 N N . ARG E 1 142 ? 46.026 -75.700 67.791 1.00 197.08 ? 142 ARG E N 1 +ATOM 8701 C CA . ARG E 1 142 ? 44.906 -76.607 67.701 1.00 184.77 ? 142 ARG E CA 1 +ATOM 8702 C C . ARG E 1 142 ? 45.433 -78.022 67.838 1.00 188.51 ? 142 ARG E C 1 +ATOM 8703 O O . ARG E 1 142 ? 46.536 -78.327 67.388 1.00 134.01 ? 142 ARG E O 1 +ATOM 8704 C CB . ARG E 1 142 ? 44.133 -76.419 66.386 1.00 164.05 ? 142 ARG E CB 1 +ATOM 8705 C CG . ARG E 1 142 ? 42.894 -77.299 66.297 1.00 147.25 ? 142 ARG E CG 1 +ATOM 8706 C CD . ARG E 1 142 ? 41.678 -76.583 65.741 1.00 147.77 ? 142 ARG E CD 1 +ATOM 8707 N NE . ARG E 1 142 ? 41.458 -76.762 64.319 1.00 173.48 ? 142 ARG E NE 1 +ATOM 8708 C CZ . ARG E 1 142 ? 40.671 -75.972 63.591 1.00 182.08 ? 142 ARG E CZ 1 +ATOM 8709 N NH1 . ARG E 1 142 ? 40.199 -74.823 64.084 1.00 199.32 ? 142 ARG E NH1 1 +ATOM 8710 N NH2 . ARG E 1 142 ? 40.442 -76.285 62.329 1.00 157.47 ? 142 ARG E NH2 1 +ATOM 8711 N N . TYR E 1 143 ? 44.647 -78.867 68.496 1.00 218.79 ? 143 TYR E N 1 +ATOM 8712 C CA . TYR E 1 143 ? 45.054 -80.224 68.825 1.00 223.04 ? 143 TYR E CA 1 +ATOM 8713 C C . TYR E 1 143 ? 43.967 -81.221 68.403 1.00 199.26 ? 143 TYR E C 1 +ATOM 8714 O O . TYR E 1 143 ? 43.153 -81.668 69.213 1.00 191.18 ? 143 TYR E O 1 +ATOM 8715 C CB . TYR E 1 143 ? 45.348 -80.332 70.327 1.00 224.13 ? 143 TYR E CB 1 +ATOM 8716 C CG . TYR E 1 143 ? 45.905 -81.668 70.713 1.00 231.02 ? 143 TYR E CG 1 +ATOM 8717 C CD1 . TYR E 1 143 ? 47.178 -82.045 70.315 1.00 215.44 ? 143 TYR E CD1 1 +ATOM 8718 C CD2 . TYR E 1 143 ? 45.128 -82.589 71.400 1.00 243.79 ? 143 TYR E CD2 1 +ATOM 8719 C CE1 . TYR E 1 143 ? 47.679 -83.297 70.615 1.00 236.61 ? 143 TYR E CE1 1 +ATOM 8720 C CE2 . TYR E 1 143 ? 45.619 -83.843 71.715 1.00 248.76 ? 143 TYR E CE2 1 +ATOM 8721 C CZ . TYR E 1 143 ? 46.895 -84.194 71.315 1.00 255.62 ? 143 TYR E CZ 1 +ATOM 8722 O OH . TYR E 1 143 ? 47.391 -85.443 71.614 1.00 269.34 ? 143 TYR E OH 1 +ATOM 8723 N N . GLY E 1 145 ? 41.429 -81.556 67.534 1.00 108.61 ? 145 GLY E N 1 +ATOM 8724 C CA . GLY E 1 145 ? 40.040 -81.121 67.541 1.00 142.88 ? 145 GLY E CA 1 +ATOM 8725 C C . GLY E 1 145 ? 39.749 -79.802 68.260 1.00 198.89 ? 145 GLY E C 1 +ATOM 8726 O O . GLY E 1 145 ? 38.775 -79.128 67.913 1.00 200.84 ? 145 GLY E O 1 +ATOM 8727 N N . ILE E 1 146 ? 40.557 -79.439 69.265 1.00 227.77 ? 146 ILE E N 1 +ATOM 8728 C CA . ILE E 1 146 ? 40.291 -78.270 70.139 1.00 195.52 ? 146 ILE E CA 1 +ATOM 8729 C C . ILE E 1 146 ? 41.378 -77.207 69.921 1.00 208.87 ? 146 ILE E C 1 +ATOM 8730 O O . ILE E 1 146 ? 42.553 -77.543 69.794 1.00 149.57 ? 146 ILE E O 1 +ATOM 8731 C CB . ILE E 1 146 ? 40.257 -78.657 71.643 1.00 145.90 ? 146 ILE E CB 1 +ATOM 8732 C CG1 . ILE E 1 146 ? 39.562 -80.015 71.833 1.00 139.51 ? 146 ILE E CG1 1 +ATOM 8733 C CG2 . ILE E 1 146 ? 39.557 -77.578 72.461 1.00 114.07 ? 146 ILE E CG2 1 +ATOM 8734 C CD1 . ILE E 1 146 ? 40.511 -81.196 71.921 1.00 114.73 ? 146 ILE E CD1 1 +ATOM 8735 N N . GLY E 1 147 ? 40.991 -75.933 69.828 1.00 229.15 ? 147 GLY E N 1 +ATOM 8736 C CA . GLY E 1 147 ? 41.958 -74.881 69.492 1.00 211.16 ? 147 GLY E CA 1 +ATOM 8737 C C . GLY E 1 147 ? 41.671 -73.502 70.049 1.00 215.11 ? 147 GLY E C 1 +ATOM 8738 O O . GLY E 1 147 ? 40.526 -73.156 70.343 1.00 224.95 ? 147 GLY E O 1 +ATOM 8739 N N . ALA E 1 148 ? 42.725 -72.708 70.193 1.00 203.01 ? 148 ALA E N 1 +ATOM 8740 C CA . ALA E 1 148 ? 42.579 -71.306 70.561 1.00 208.30 ? 148 ALA E CA 1 +ATOM 8741 C C . ALA E 1 148 ? 43.678 -70.470 69.910 1.00 200.08 ? 148 ALA E C 1 +ATOM 8742 O O . ALA E 1 148 ? 44.657 -71.014 69.398 1.00 189.05 ? 148 ALA E O 1 +ATOM 8743 C CB . ALA E 1 148 ? 42.583 -71.149 72.081 1.00 181.80 ? 148 ALA E CB 1 +ATOM 8744 N N . ASP E 1 149 ? 43.494 -69.151 69.917 1.00 178.20 ? 149 ASP E N 1 +ATOM 8745 C CA . ASP E 1 149 ? 44.502 -68.232 69.401 1.00 151.22 ? 149 ASP E CA 1 +ATOM 8746 C C . ASP E 1 149 ? 44.256 -66.814 69.886 1.00 168.20 ? 149 ASP E C 1 +ATOM 8747 O O . ASP E 1 149 ? 43.111 -66.427 70.078 1.00 128.61 ? 149 ASP E O 1 +ATOM 8748 C CB . ASP E 1 149 ? 44.532 -68.240 67.873 1.00 132.79 ? 149 ASP E CB 1 +ATOM 8749 C CG . ASP E 1 149 ? 45.711 -67.401 67.321 1.00 125.16 ? 149 ASP E CG 1 +ATOM 8750 O OD1 . ASP E 1 149 ? 46.461 -66.757 68.116 1.00 173.24 ? 149 ASP E OD1 1 +ATOM 8751 O OD2 . ASP E 1 149 ? 45.855 -67.273 66.088 1.00 107.30 ? 149 ASP E OD2 1 +ATOM 8752 N N . THR E 1 150 ? 45.330 -66.064 70.130 1.00 191.49 ? 150 THR E N 1 +ATOM 8753 C CA . THR E 1 150 ? 45.208 -64.616 70.257 1.00 172.74 ? 150 THR E CA 1 +ATOM 8754 C C . THR E 1 150 ? 46.092 -63.930 69.222 1.00 197.70 ? 150 THR E C 1 +ATOM 8755 O O . THR E 1 150 ? 47.070 -64.504 68.730 1.00 218.33 ? 150 THR E O 1 +ATOM 8756 C CB . THR E 1 150 ? 45.598 -64.105 71.652 1.00 142.02 ? 150 THR E CB 1 +ATOM 8757 O OG1 . THR E 1 150 ? 46.958 -64.473 71.935 1.00 165.17 ? 150 THR E OG1 1 +ATOM 8758 C CG2 . THR E 1 150 ? 44.681 -64.670 72.705 1.00 119.18 ? 150 THR E CG2 1 +ATOM 8759 N N . GLN E 1 151 ? 45.695 -62.724 68.856 1.00 200.45 ? 151 GLN E N 1 +ATOM 8760 C CA . GLN E 1 151 ? 46.474 -61.897 67.967 1.00 164.91 ? 151 GLN E CA 1 +ATOM 8761 C C . GLN E 1 151 ? 46.430 -60.488 68.525 1.00 164.03 ? 151 GLN E C 1 +ATOM 8762 O O . GLN E 1 151 ? 45.412 -60.061 69.065 1.00 188.61 ? 151 GLN E O 1 +ATOM 8763 C CB . GLN E 1 151 ? 45.876 -61.956 66.562 1.00 168.42 ? 151 GLN E CB 1 +ATOM 8764 C CG . GLN E 1 151 ? 46.138 -63.282 65.831 1.00 157.94 ? 151 GLN E CG 1 +ATOM 8765 C CD . GLN E 1 151 ? 45.223 -63.491 64.591 1.00 172.25 ? 151 GLN E CD 1 +ATOM 8766 O OE1 . GLN E 1 151 ? 45.412 -64.307 63.591 1.00 176.75 ? 151 GLN E OE1 1 +ATOM 8767 N NE2 . GLN E 1 151 ? 44.176 -62.759 64.667 1.00 177.70 ? 151 GLN E NE2 1 +ATOM 8768 N N . TYR E 1 152 ? 47.535 -59.770 68.443 1.00 139.26 ? 152 TYR E N 1 +ATOM 8769 C CA . TYR E 1 152 ? 47.537 -58.386 68.882 1.00 159.04 ? 152 TYR E CA 1 +ATOM 8770 C C . TYR E 1 152 ? 48.245 -57.472 67.899 1.00 192.13 ? 152 TYR E C 1 +ATOM 8771 O O . TYR E 1 152 ? 49.188 -57.886 67.228 1.00 164.62 ? 152 TYR E O 1 +ATOM 8772 C CB . TYR E 1 152 ? 48.146 -58.274 70.278 1.00 139.19 ? 152 TYR E CB 1 +ATOM 8773 C CG . TYR E 1 152 ? 49.556 -57.718 70.368 1.00 149.29 ? 152 TYR E CG 1 +ATOM 8774 C CD1 . TYR E 1 152 ? 50.643 -58.395 69.821 1.00 162.52 ? 152 TYR E CD1 1 +ATOM 8775 C CD2 . TYR E 1 152 ? 49.814 -56.574 71.104 1.00 138.58 ? 152 TYR E CD2 1 +ATOM 8776 C CE1 . TYR E 1 152 ? 51.940 -57.888 69.925 1.00 139.47 ? 152 TYR E CE1 1 +ATOM 8777 C CE2 . TYR E 1 152 ? 51.106 -56.078 71.241 1.00 133.85 ? 152 TYR E CE2 1 +ATOM 8778 C CZ . TYR E 1 152 ? 52.163 -56.729 70.633 1.00 128.66 ? 152 TYR E CZ 1 +ATOM 8779 O OH . TYR E 1 152 ? 53.433 -56.231 70.766 1.00 107.76 ? 152 TYR E OH 1 +ATOM 8780 N N . GLN E 1 153 ? 47.745 -56.241 67.781 1.00 206.70 ? 153 GLN E N 1 +ATOM 8781 C CA . GLN E 1 153 ? 48.437 -55.211 67.018 1.00 189.15 ? 153 GLN E CA 1 +ATOM 8782 C C . GLN E 1 153 ? 48.444 -53.906 67.804 1.00 159.23 ? 153 GLN E C 1 +ATOM 8783 O O . GLN E 1 153 ? 47.586 -53.680 68.665 1.00 93.07 ? 153 GLN E O 1 +ATOM 8784 C CB . GLN E 1 153 ? 47.757 -54.999 65.659 1.00 207.61 ? 153 GLN E CB 1 +ATOM 8785 C CG . GLN E 1 153 ? 47.857 -56.201 64.728 1.00 202.97 ? 153 GLN E CG 1 +ATOM 8786 C CD . GLN E 1 153 ? 46.801 -57.291 64.976 1.00 177.86 ? 153 GLN E CD 1 +ATOM 8787 O OE1 . GLN E 1 153 ? 45.920 -57.158 65.837 1.00 153.35 ? 153 GLN E OE1 1 +ATOM 8788 N NE2 . GLN E 1 153 ? 46.854 -58.348 64.172 1.00 131.20 ? 153 GLN E NE2 1 +ATOM 8789 N N . LEU E 1 154 ? 49.463 -53.080 67.568 1.00 166.07 ? 154 LEU E N 1 +ATOM 8790 C CA . LEU E 1 154 ? 49.486 -51.748 68.185 1.00 141.97 ? 154 LEU E CA 1 +ATOM 8791 C C . LEU E 1 154 ? 50.073 -50.672 67.266 1.00 144.85 ? 154 LEU E C 1 +ATOM 8792 O O . LEU E 1 154 ? 51.022 -50.919 66.497 1.00 87.25 ? 154 LEU E O 1 +ATOM 8793 C CB . LEU E 1 154 ? 50.222 -51.760 69.527 1.00 107.43 ? 154 LEU E CB 1 +ATOM 8794 C CG . LEU E 1 154 ? 51.744 -51.919 69.428 1.00 166.21 ? 154 LEU E CG 1 +ATOM 8795 C CD1 . LEU E 1 154 ? 52.449 -50.572 69.449 1.00 167.10 ? 154 LEU E CD1 1 +ATOM 8796 C CD2 . LEU E 1 154 ? 52.238 -52.811 70.555 1.00 216.43 ? 154 LEU E CD2 1 +ATOM 8797 N N . ASP E 1 155 ? 49.515 -49.473 67.428 1.00 136.98 ? 155 ASP E N 1 +ATOM 8798 C CA . ASP E 1 155 ? 49.718 -48.346 66.527 1.00 106.40 ? 155 ASP E CA 1 +ATOM 8799 C C . ASP E 1 155 ? 50.239 -47.185 67.319 1.00 76.21 ? 155 ASP E C 1 +ATOM 8800 O O . ASP E 1 155 ? 50.130 -47.177 68.566 1.00 93.19 ? 155 ASP E O 1 +ATOM 8801 C CB . ASP E 1 155 ? 48.384 -47.944 65.897 1.00 134.80 ? 155 ASP E CB 1 +ATOM 8802 C CG . ASP E 1 155 ? 47.604 -49.137 65.343 1.00 161.60 ? 155 ASP E CG 1 +ATOM 8803 O OD1 . ASP E 1 155 ? 46.927 -49.836 66.137 1.00 122.95 ? 155 ASP E OD1 1 +ATOM 8804 O OD2 . ASP E 1 155 ? 47.644 -49.353 64.108 1.00 162.39 ? 155 ASP E OD2 1 +ATOM 8805 N N . GLN E 1 156 ? 50.838 -46.212 66.642 1.00 77.77 ? 156 GLN E N 1 +ATOM 8806 C CA . GLN E 1 156 ? 51.420 -45.042 67.358 1.00 137.29 ? 156 GLN E CA 1 +ATOM 8807 C C . GLN E 1 156 ? 50.762 -43.729 66.952 1.00 140.67 ? 156 GLN E C 1 +ATOM 8808 O O . GLN E 1 156 ? 50.118 -43.657 65.917 1.00 164.41 ? 156 GLN E O 1 +ATOM 8809 C CB . GLN E 1 156 ? 52.918 -44.927 67.098 1.00 147.27 ? 156 GLN E CB 1 +ATOM 8810 C CG . GLN E 1 156 ? 53.638 -43.936 67.995 1.00 131.38 ? 156 GLN E CG 1 +ATOM 8811 C CD . GLN E 1 156 ? 55.131 -44.187 68.042 1.00 140.39 ? 156 GLN E CD 1 +ATOM 8812 O OE1 . GLN E 1 156 ? 55.679 -44.996 67.271 1.00 127.40 ? 156 GLN E OE1 1 +ATOM 8813 N NE2 . GLN E 1 156 ? 55.810 -43.489 68.948 1.00 152.42 ? 156 GLN E NE2 1 +ATOM 8814 N N . ILE E 1 157 ? 50.813 -42.742 67.841 1.00 109.54 ? 157 ILE E N 1 +ATOM 8815 C CA . ILE E 1 157 ? 50.214 -41.452 67.569 1.00 111.49 ? 157 ILE E CA 1 +ATOM 8816 C C . ILE E 1 157 ? 51.023 -40.426 68.350 1.00 137.71 ? 157 ILE E C 1 +ATOM 8817 O O . ILE E 1 157 ? 51.403 -40.661 69.510 1.00 243.02 ? 157 ILE E O 1 +ATOM 8818 C CB . ILE E 1 157 ? 48.708 -41.414 67.950 1.00 102.59 ? 157 ILE E CB 1 +ATOM 8819 C CG1 . ILE E 1 157 ? 47.988 -40.330 67.168 1.00 117.59 ? 157 ILE E CG1 1 +ATOM 8820 C CG2 . ILE E 1 157 ? 48.521 -41.169 69.445 1.00 114.96 ? 157 ILE E CG2 1 +ATOM 8821 C CD1 . ILE E 1 157 ? 46.477 -40.330 67.342 1.00 136.25 ? 157 ILE E CD1 1 +ATOM 8822 N N . ALA E 1 158 ? 51.338 -39.305 67.722 1.00 148.87 ? 158 ALA E N 1 +ATOM 8823 C CA . ALA E 1 158 ? 52.153 -38.300 68.397 1.00 128.27 ? 158 ALA E CA 1 +ATOM 8824 C C . ALA E 1 158 ? 51.545 -36.929 68.202 1.00 112.00 ? 158 ALA E C 1 +ATOM 8825 O O . ALA E 1 158 ? 50.840 -36.670 67.222 1.00 69.52 ? 158 ALA E O 1 +ATOM 8826 C CB . ALA E 1 158 ? 53.596 -38.339 67.905 1.00 99.28 ? 158 ALA E CB 1 +ATOM 8827 N N . VAL E 1 159 ? 51.789 -36.068 69.180 1.00 96.84 ? 159 VAL E N 1 +ATOM 8828 C CA . VAL E 1 159 ? 51.185 -34.754 69.188 1.00 95.12 ? 159 VAL E CA 1 +ATOM 8829 C C . VAL E 1 159 ? 52.213 -33.709 69.582 1.00 91.80 ? 159 VAL E C 1 +ATOM 8830 O O . VAL E 1 159 ? 52.894 -33.849 70.608 1.00 122.21 ? 159 VAL E O 1 +ATOM 8831 C CB . VAL E 1 159 ? 49.967 -34.718 70.145 1.00 99.48 ? 159 VAL E CB 1 +ATOM 8832 C CG1 . VAL E 1 159 ? 49.628 -33.294 70.555 1.00 96.17 ? 159 VAL E CG1 1 +ATOM 8833 C CG2 . VAL E 1 159 ? 48.759 -35.369 69.484 1.00 105.43 ? 159 VAL E CG2 1 +ATOM 8834 N N . ASN E 1 160 ? 52.321 -32.668 68.764 1.00 72.56 ? 160 ASN E N 1 +ATOM 8835 C CA . ASN E 1 160 ? 53.072 -31.482 69.132 1.00 70.49 ? 160 ASN E CA 1 +ATOM 8836 C C . ASN E 1 160 ? 52.121 -30.445 69.717 1.00 76.63 ? 160 ASN E C 1 +ATOM 8837 O O . ASN E 1 160 ? 51.036 -30.177 69.149 1.00 94.68 ? 160 ASN E O 1 +ATOM 8838 C CB . ASN E 1 160 ? 53.758 -30.920 67.898 1.00 63.74 ? 160 ASN E CB 1 +ATOM 8839 C CG . ASN E 1 160 ? 54.533 -29.620 68.175 1.00 65.54 ? 160 ASN E CG 1 +ATOM 8840 O OD1 . ASN E 1 160 ? 53.998 -28.663 68.749 1.00 54.83 ? 160 ASN E OD1 1 +ATOM 8841 N ND2 . ASN E 1 160 ? 55.731 -29.521 67.601 1.00 57.24 ? 160 ASN E ND2 1 +ATOM 8842 N N . LEU E 1 161 ? 52.492 -29.889 70.865 1.00 53.46 ? 161 LEU E N 1 +ATOM 8843 C CA . LEU E 1 161 ? 51.880 -28.672 71.311 1.00 53.75 ? 161 LEU E CA 1 +ATOM 8844 C C . LEU E 1 161 ? 52.952 -27.664 71.503 1.00 50.18 ? 161 LEU E C 1 +ATOM 8845 O O . LEU E 1 161 ? 54.022 -27.979 72.020 1.00 78.53 ? 161 LEU E O 1 +ATOM 8846 C CB . LEU E 1 161 ? 51.071 -28.898 72.600 1.00 61.64 ? 161 LEU E CB 1 +ATOM 8847 C CG . LEU E 1 161 ? 49.843 -29.792 72.477 1.00 71.65 ? 161 LEU E CG 1 +ATOM 8848 C CD1 . LEU E 1 161 ? 49.255 -30.092 73.853 1.00 96.78 ? 161 LEU E CD1 1 +ATOM 8849 C CD2 . LEU E 1 161 ? 48.796 -29.135 71.590 1.00 64.71 ? 161 LEU E CD2 1 +ATOM 8850 N N . ARG E 1 162 ? 52.625 -26.399 71.304 1.00 64.76 ? 162 ARG E N 1 +ATOM 8851 C CA . ARG E 1 162 ? 53.609 -25.355 71.598 1.00 94.82 ? 162 ARG E CA 1 +ATOM 8852 C C . ARG E 1 162 ? 53.034 -23.967 71.971 1.00 68.01 ? 162 ARG E C 1 +ATOM 8853 O O . ARG E 1 162 ? 52.137 -23.470 71.326 1.00 85.18 ? 162 ARG E O 1 +ATOM 8854 C CB . ARG E 1 162 ? 54.590 -25.259 70.424 1.00 108.38 ? 162 ARG E CB 1 +ATOM 8855 C CG . ARG E 1 162 ? 54.000 -24.845 69.086 1.00 117.85 ? 162 ARG E CG 1 +ATOM 8856 C CD . ARG E 1 162 ? 55.117 -24.411 68.138 1.00 123.03 ? 162 ARG E CD 1 +ATOM 8857 N NE . ARG E 1 162 ? 54.651 -23.793 66.886 1.00 92.98 ? 162 ARG E NE 1 +ATOM 8858 C CZ . ARG E 1 162 ? 54.246 -24.460 65.819 1.00 75.96 ? 162 ARG E CZ 1 +ATOM 8859 N NH1 . ARG E 1 162 ? 54.152 -25.787 65.864 1.00 95.77 ? 162 ARG E NH1 1 +ATOM 8860 N NH2 . ARG E 1 162 ? 53.898 -23.798 64.730 1.00 61.05 ? 162 ARG E NH2 1 +ATOM 8861 N N . VAL E 1 163 ? 53.611 -23.366 73.008 1.00 55.20 ? 163 VAL E N 1 +ATOM 8862 C CA . VAL E 1 163 ? 53.216 -22.062 73.493 1.00 55.23 ? 163 VAL E CA 1 +ATOM 8863 C C . VAL E 1 163 ? 53.972 -21.038 72.725 1.00 54.41 ? 163 VAL E C 1 +ATOM 8864 O O . VAL E 1 163 ? 55.201 -20.972 72.811 1.00 63.98 ? 163 VAL E O 1 +ATOM 8865 C CB . VAL E 1 163 ? 53.584 -21.861 74.980 1.00 79.68 ? 163 VAL E CB 1 +ATOM 8866 C CG1 . VAL E 1 163 ? 53.198 -20.460 75.439 1.00 80.28 ? 163 VAL E CG1 1 +ATOM 8867 C CG2 . VAL E 1 163 ? 52.917 -22.942 75.850 1.00 108.22 ? 163 VAL E CG2 1 +ATOM 8868 N N . VAL E 1 164 ? 53.216 -20.146 72.102 1.00 67.44 ? 164 VAL E N 1 +ATOM 8869 C CA . VAL E 1 164 ? 53.752 -19.001 71.372 1.00 80.39 ? 164 VAL E CA 1 +ATOM 8870 C C . VAL E 1 164 ? 53.388 -17.671 72.024 1.00 64.78 ? 164 VAL E C 1 +ATOM 8871 O O . VAL E 1 164 ? 52.292 -17.510 72.530 1.00 45.60 ? 164 VAL E O 1 +ATOM 8872 C CB . VAL E 1 164 ? 53.171 -18.917 69.976 1.00 75.09 ? 164 VAL E CB 1 +ATOM 8873 C CG1 . VAL E 1 164 ? 53.756 -17.718 69.263 1.00 92.91 ? 164 VAL E CG1 1 +ATOM 8874 C CG2 . VAL E 1 164 ? 53.507 -20.177 69.236 1.00 88.21 ? 164 VAL E CG2 1 +ATOM 8875 N N . ASN E 1 165 ? 54.400 -16.814 72.181 1.00 76.95 ? 165 ASN E N 1 +ATOM 8876 C CA . ASN E 1 165 ? 54.234 -15.548 72.885 1.00 80.99 ? 165 ASN E CA 1 +ATOM 8877 C C . ASN E 1 165 ? 53.709 -14.513 71.899 1.00 82.66 ? 165 ASN E C 1 +ATOM 8878 O O . ASN E 1 165 ? 54.380 -14.223 70.905 1.00 90.20 ? 165 ASN E O 1 +ATOM 8879 C CB . ASN E 1 165 ? 55.551 -15.056 73.530 1.00 60.25 ? 165 ASN E CB 1 +ATOM 8880 C CG . ASN E 1 165 ? 55.316 -13.888 74.456 1.00 64.44 ? 165 ASN E CG 1 +ATOM 8881 O OD1 . ASN E 1 165 ? 54.156 -13.470 74.654 1.00 85.34 ? 165 ASN E OD1 1 +ATOM 8882 N ND2 . ASN E 1 165 ? 56.371 -13.194 74.792 1.00 76.96 ? 165 ASN E ND2 1 +ATOM 8883 N N . VAL E 1 166 ? 52.532 -13.962 72.195 1.00 68.69 ? 166 VAL E N 1 +ATOM 8884 C CA . VAL E 1 166 ? 51.836 -13.077 71.269 1.00 62.07 ? 166 VAL E CA 1 +ATOM 8885 C C . VAL E 1 166 ? 52.635 -11.855 71.096 1.00 50.59 ? 166 VAL E C 1 +ATOM 8886 O O . VAL E 1 166 ? 52.769 -11.339 69.998 1.00 44.66 ? 166 VAL E O 1 +ATOM 8887 C CB . VAL E 1 166 ? 50.438 -12.705 71.806 1.00 79.32 ? 166 VAL E CB 1 +ATOM 8888 C CG1 . VAL E 1 166 ? 49.990 -11.353 71.278 1.00 69.83 ? 166 VAL E CG1 1 +ATOM 8889 C CG2 . VAL E 1 166 ? 49.413 -13.831 71.485 1.00 82.13 ? 166 VAL E CG2 1 +ATOM 8890 N N . SER E 1 167 ? 53.236 -11.428 72.188 1.00 67.05 ? 167 SER E N 1 +ATOM 8891 C CA . SER E 1 167 ? 53.969 -10.169 72.197 1.00 94.81 ? 167 SER E CA 1 +ATOM 8892 C C . SER E 1 167 ? 55.262 -10.180 71.340 1.00 73.96 ? 167 SER E C 1 +ATOM 8893 O O . SER E 1 167 ? 55.834 -9.109 71.099 1.00 64.21 ? 167 SER E O 1 +ATOM 8894 C CB . SER E 1 167 ? 54.261 -9.758 73.650 1.00 103.65 ? 167 SER E CB 1 +ATOM 8895 O OG . SER E 1 167 ? 53.110 -9.960 74.462 1.00 111.88 ? 167 SER E OG 1 +ATOM 8896 N N . THR E 1 168 ? 55.721 -11.363 70.922 1.00 52.36 ? 168 THR E N 1 +ATOM 8897 C CA . THR E 1 168 ? 56.997 -11.471 70.238 1.00 60.69 ? 168 THR E CA 1 +ATOM 8898 C C . THR E 1 168 ? 56.997 -12.451 69.075 1.00 59.40 ? 168 THR E C 1 +ATOM 8899 O O . THR E 1 168 ? 57.726 -12.296 68.083 1.00 61.33 ? 168 THR E O 1 +ATOM 8900 C CB . THR E 1 168 ? 58.151 -11.874 71.197 1.00 63.17 ? 168 THR E CB 1 +ATOM 8901 O OG1 . THR E 1 168 ? 57.789 -13.041 71.934 1.00 78.39 ? 168 THR E OG1 1 +ATOM 8902 C CG2 . THR E 1 168 ? 58.506 -10.732 72.172 1.00 62.54 ? 168 THR E CG2 1 +ATOM 8903 N N . GLY E 1 169 ? 56.259 -13.514 69.233 1.00 59.98 ? 169 GLY E N 1 +ATOM 8904 C CA . GLY E 1 169 ? 56.348 -14.563 68.265 1.00 76.82 ? 169 GLY E CA 1 +ATOM 8905 C C . GLY E 1 169 ? 57.403 -15.581 68.624 1.00 100.78 ? 169 GLY E C 1 +ATOM 8906 O O . GLY E 1 169 ? 57.388 -16.696 68.070 1.00 211.70 ? 169 GLY E O 1 +ATOM 8907 N N . GLU E 1 170 ? 58.223 -15.296 69.637 1.00 90.75 ? 170 GLU E N 1 +ATOM 8908 C CA . GLU E 1 170 ? 59.000 -16.359 70.308 1.00 105.79 ? 170 GLU E CA 1 +ATOM 8909 C C . GLU E 1 170 ? 58.090 -17.528 70.728 1.00 86.59 ? 170 GLU E C 1 +ATOM 8910 O O . GLU E 1 170 ? 57.099 -17.342 71.387 1.00 89.59 ? 170 GLU E O 1 +ATOM 8911 C CB . GLU E 1 170 ? 59.748 -15.842 71.557 1.00 105.25 ? 170 GLU E CB 1 +ATOM 8912 C CG . GLU E 1 170 ? 60.962 -14.975 71.229 1.00 111.11 ? 170 GLU E CG 1 +ATOM 8913 C CD . GLU E 1 170 ? 61.184 -13.832 72.198 1.00 112.47 ? 170 GLU E CD 1 +ATOM 8914 O OE1 . GLU E 1 170 ? 60.269 -13.546 73.015 1.00 114.89 ? 170 GLU E OE1 1 +ATOM 8915 O OE2 . GLU E 1 170 ? 62.224 -13.142 72.076 1.00 133.22 ? 170 GLU E OE2 1 +ATOM 8916 N N . ILE E 1 171 ? 58.392 -18.725 70.271 1.00 69.31 ? 171 ILE E N 1 +ATOM 8917 C CA . ILE E 1 171 ? 57.830 -19.876 70.874 1.00 74.74 ? 171 ILE E CA 1 +ATOM 8918 C C . ILE E 1 171 ? 58.415 -20.024 72.296 1.00 127.34 ? 171 ILE E C 1 +ATOM 8919 O O . ILE E 1 171 ? 59.646 -20.049 72.485 1.00 220.70 ? 171 ILE E O 1 +ATOM 8920 C CB . ILE E 1 171 ? 58.156 -21.095 70.040 1.00 73.23 ? 171 ILE E CB 1 +ATOM 8921 C CG1 . ILE E 1 171 ? 57.374 -21.020 68.756 1.00 68.32 ? 171 ILE E CG1 1 +ATOM 8922 C CG2 . ILE E 1 171 ? 57.834 -22.360 70.833 1.00 102.62 ? 171 ILE E CG2 1 +ATOM 8923 C CD1 . ILE E 1 171 ? 57.899 -21.984 67.712 1.00 102.01 ? 171 ILE E CD1 1 +ATOM 8924 N N . LEU E 1 172 ? 57.549 -20.127 73.300 1.00 146.17 ? 172 LEU E N 1 +ATOM 8925 C CA . LEU E 1 172 ? 58.008 -20.199 74.689 1.00 153.10 ? 172 LEU E CA 1 +ATOM 8926 C C . LEU E 1 172 ? 58.148 -21.642 75.205 1.00 133.16 ? 172 LEU E C 1 +ATOM 8927 O O . LEU E 1 172 ? 58.771 -21.920 76.259 1.00 171.17 ? 172 LEU E O 1 +ATOM 8928 C CB . LEU E 1 172 ? 57.073 -19.422 75.608 1.00 158.85 ? 172 LEU E CB 1 +ATOM 8929 C CG . LEU E 1 172 ? 57.132 -17.883 75.420 1.00 185.41 ? 172 LEU E CG 1 +ATOM 8930 C CD1 . LEU E 1 172 ? 56.322 -17.034 76.417 1.00 168.79 ? 172 LEU E CD1 1 +ATOM 8931 C CD2 . LEU E 1 172 ? 58.558 -17.359 75.298 1.00 204.83 ? 172 LEU E CD2 1 +ATOM 8932 N N . SER E 1 173 ? 57.591 -22.566 74.448 1.00 88.52 ? 173 SER E N 1 +ATOM 8933 C CA . SER E 1 173 ? 57.710 -23.965 74.772 1.00 112.46 ? 173 SER E CA 1 +ATOM 8934 C C . SER E 1 173 ? 57.214 -24.835 73.614 1.00 114.62 ? 173 SER E C 1 +ATOM 8935 O O . SER E 1 173 ? 56.117 -24.633 73.105 1.00 188.53 ? 173 SER E O 1 +ATOM 8936 C CB . SER E 1 173 ? 56.877 -24.266 76.017 1.00 151.94 ? 173 SER E CB 1 +ATOM 8937 O OG . SER E 1 173 ? 56.667 -25.663 76.174 1.00 241.01 ? 173 SER E OG 1 +ATOM 8938 N N . SER E 1 174 ? 57.981 -25.853 73.252 1.00 96.39 ? 174 SER E N 1 +ATOM 8939 C CA . SER E 1 174 ? 57.482 -26.905 72.383 1.00 87.75 ? 174 SER E CA 1 +ATOM 8940 C C . SER E 1 174 ? 57.564 -28.245 73.115 1.00 98.22 ? 174 SER E C 1 +ATOM 8941 O O . SER E 1 174 ? 58.577 -28.557 73.746 1.00 152.94 ? 174 SER E O 1 +ATOM 8942 C CB . SER E 1 174 ? 58.294 -26.948 71.075 1.00 76.38 ? 174 SER E CB 1 +ATOM 8943 O OG . SER E 1 174 ? 57.704 -27.787 70.094 1.00 81.40 ? 174 SER E OG 1 +ATOM 8944 N N . VAL E 1 175 ? 56.522 -29.062 72.988 1.00 83.48 ? 175 VAL E N 1 +ATOM 8945 C CA . VAL E 1 175 ? 56.518 -30.406 73.555 1.00 81.36 ? 175 VAL E CA 1 +ATOM 8946 C C . VAL E 1 175 ? 55.996 -31.442 72.574 1.00 78.39 ? 175 VAL E C 1 +ATOM 8947 O O . VAL E 1 175 ? 55.060 -31.191 71.822 1.00 68.13 ? 175 VAL E O 1 +ATOM 8948 C CB . VAL E 1 175 ? 55.680 -30.454 74.857 1.00 104.68 ? 175 VAL E CB 1 +ATOM 8949 C CG1 . VAL E 1 175 ? 56.301 -29.546 75.915 1.00 132.01 ? 175 VAL E CG1 1 +ATOM 8950 C CG2 . VAL E 1 175 ? 54.257 -30.032 74.612 1.00 102.99 ? 175 VAL E CG2 1 +ATOM 8951 N N . ASN E 1 176 ? 56.552 -32.651 72.660 1.00 120.10 ? 176 ASN E N 1 +ATOM 8952 C CA . ASN E 1 176 ? 56.235 -33.750 71.720 1.00 136.86 ? 176 ASN E CA 1 +ATOM 8953 C C . ASN E 1 176 ? 55.781 -35.063 72.398 1.00 117.27 ? 176 ASN E C 1 +ATOM 8954 O O . ASN E 1 176 ? 56.623 -35.862 72.772 1.00 89.95 ? 176 ASN E O 1 +ATOM 8955 C CB . ASN E 1 176 ? 57.492 -34.030 70.877 1.00 130.27 ? 176 ASN E CB 1 +ATOM 8956 C CG . ASN E 1 176 ? 57.468 -33.345 69.515 1.00 156.14 ? 176 ASN E CG 1 +ATOM 8957 O OD1 . ASN E 1 176 ? 58.296 -33.622 68.602 1.00 92.54 ? 176 ASN E OD1 1 +ATOM 8958 N ND2 . ASN E 1 176 ? 56.524 -32.415 69.375 1.00 184.89 ? 176 ASN E ND2 1 +ATOM 8959 N N . THR E 1 177 ? 54.469 -35.266 72.575 1.00 103.07 ? 177 THR E N 1 +ATOM 8960 C CA . THR E 1 177 ? 53.959 -36.433 73.310 1.00 92.11 ? 177 THR E CA 1 +ATOM 8961 C C . THR E 1 177 ? 53.584 -37.540 72.344 1.00 117.73 ? 177 THR E C 1 +ATOM 8962 O O . THR E 1 177 ? 53.359 -37.291 71.156 1.00 129.49 ? 177 THR E O 1 +ATOM 8963 C CB . THR E 1 177 ? 52.743 -36.095 74.201 1.00 73.19 ? 177 THR E CB 1 +ATOM 8964 O OG1 . THR E 1 177 ? 51.623 -35.778 73.379 1.00 66.07 ? 177 THR E OG1 1 +ATOM 8965 C CG2 . THR E 1 177 ? 53.045 -34.897 75.109 1.00 71.01 ? 177 THR E CG2 1 +ATOM 8966 N N . SER E 1 178 ? 53.515 -38.762 72.865 1.00 140.79 ? 178 SER E N 1 +ATOM 8967 C CA . SER E 1 178 ? 53.243 -39.950 72.048 1.00 164.62 ? 178 SER E CA 1 +ATOM 8968 C C . SER E 1 178 ? 52.469 -41.005 72.843 1.00 136.74 ? 178 SER E C 1 +ATOM 8969 O O . SER E 1 178 ? 52.521 -41.051 74.055 1.00 101.16 ? 178 SER E O 1 +ATOM 8970 C CB . SER E 1 178 ? 54.539 -40.586 71.533 1.00 160.52 ? 178 SER E CB 1 +ATOM 8971 O OG . SER E 1 178 ? 54.292 -41.892 71.011 1.00 109.17 ? 178 SER E OG 1 +ATOM 8972 N N . LYS E 1 179 ? 51.730 -41.843 72.130 1.00 140.05 ? 179 LYS E N 1 +ATOM 8973 C CA . LYS E 1 179 ? 50.802 -42.750 72.781 1.00 101.14 ? 179 LYS E CA 1 +ATOM 8974 C C . LYS E 1 179 ? 50.522 -43.920 71.850 1.00 126.94 ? 179 LYS E C 1 +ATOM 8975 O O . LYS E 1 179 ? 50.436 -43.780 70.612 1.00 125.45 ? 179 LYS E O 1 +ATOM 8976 C CB . LYS E 1 179 ? 49.511 -42.019 73.155 1.00 89.53 ? 179 LYS E CB 1 +ATOM 8977 C CG . LYS E 1 179 ? 48.900 -42.455 74.456 1.00 70.06 ? 179 LYS E CG 1 +ATOM 8978 C CD . LYS E 1 179 ? 47.860 -43.512 74.189 1.00 104.40 ? 179 LYS E CD 1 +ATOM 8979 C CE . LYS E 1 179 ? 47.350 -44.091 75.495 1.00 133.96 ? 179 LYS E CE 1 +ATOM 8980 N NZ . LYS E 1 179 ? 46.563 -45.334 75.274 1.00 155.81 ? 179 LYS E NZ 1 +ATOM 8981 N N . THR E 1 180 ? 50.365 -45.082 72.459 1.00 144.12 ? 180 THR E N 1 +ATOM 8982 C CA . THR E 1 180 ? 50.198 -46.313 71.712 1.00 168.60 ? 180 THR E CA 1 +ATOM 8983 C C . THR E 1 180 ? 48.749 -46.822 71.803 1.00 167.06 ? 180 THR E C 1 +ATOM 8984 O O . THR E 1 180 ? 48.152 -46.866 72.885 1.00 104.12 ? 180 THR E O 1 +ATOM 8985 C CB . THR E 1 180 ? 51.190 -47.404 72.173 1.00 177.89 ? 180 THR E CB 1 +ATOM 8986 O OG1 . THR E 1 180 ? 50.657 -48.694 71.858 1.00 199.45 ? 180 THR E OG1 1 +ATOM 8987 C CG2 . THR E 1 180 ? 51.457 -47.302 73.663 1.00 177.81 ? 180 THR E CG2 1 +ATOM 8988 N N . ILE E 1 181 ? 48.189 -47.174 70.647 1.00 161.53 ? 181 ILE E N 1 +ATOM 8989 C CA . ILE E 1 181 ? 46.843 -47.710 70.581 1.00 140.32 ? 181 ILE E CA 1 +ATOM 8990 C C . ILE E 1 181 ? 46.901 -49.245 70.513 1.00 165.93 ? 181 ILE E C 1 +ATOM 8991 O O . ILE E 1 181 ? 47.391 -49.814 69.523 1.00 185.90 ? 181 ILE E O 1 +ATOM 8992 C CB . ILE E 1 181 ? 46.075 -47.124 69.371 1.00 111.60 ? 181 ILE E CB 1 +ATOM 8993 C CG1 . ILE E 1 181 ? 46.129 -45.603 69.399 1.00 86.86 ? 181 ILE E CG1 1 +ATOM 8994 C CG2 . ILE E 1 181 ? 44.614 -47.555 69.373 1.00 121.25 ? 181 ILE E CG2 1 +ATOM 8995 C CD1 . ILE E 1 181 ? 46.795 -45.021 68.180 1.00 121.15 ? 181 ILE E CD1 1 +ATOM 8996 N N . LEU E 1 182 ? 46.336 -49.902 71.533 1.00 143.65 ? 182 LEU E N 1 +ATOM 8997 C CA . LEU E 1 182 ? 46.298 -51.371 71.614 1.00 150.48 ? 182 LEU E CA 1 +ATOM 8998 C C . LEU E 1 182 ? 45.046 -52.049 71.000 1.00 164.92 ? 182 LEU E C 1 +ATOM 8999 O O . LEU E 1 182 ? 43.912 -51.586 71.186 1.00 134.30 ? 182 LEU E O 1 +ATOM 9000 C CB . LEU E 1 182 ? 46.397 -51.796 73.064 1.00 128.15 ? 182 LEU E CB 1 +ATOM 9001 C CG . LEU E 1 182 ? 46.386 -53.303 73.301 1.00 134.96 ? 182 LEU E CG 1 +ATOM 9002 C CD1 . LEU E 1 182 ? 47.565 -54.030 72.647 1.00 118.48 ? 182 LEU E CD1 1 +ATOM 9003 C CD2 . LEU E 1 182 ? 46.357 -53.532 74.799 1.00 151.25 ? 182 LEU E CD2 1 +ATOM 9004 N N . SER E 1 183 ? 45.271 -53.154 70.278 1.00 158.97 ? 183 SER E N 1 +ATOM 9005 C CA . SER E 1 183 ? 44.188 -53.981 69.733 1.00 137.32 ? 183 SER E CA 1 +ATOM 9006 C C . SER E 1 183 ? 44.520 -55.463 69.883 1.00 144.73 ? 183 SER E C 1 +ATOM 9007 O O . SER E 1 183 ? 45.680 -55.864 69.751 1.00 132.43 ? 183 SER E O 1 +ATOM 9008 C CB . SER E 1 183 ? 43.968 -53.677 68.259 1.00 120.05 ? 183 SER E CB 1 +ATOM 9009 O OG . SER E 1 183 ? 44.129 -52.297 67.999 1.00 142.37 ? 183 SER E OG 1 +ATOM 9010 N N . TYR E 1 184 ? 43.518 -56.261 70.250 1.00 153.00 ? 184 TYR E N 1 +ATOM 9011 C CA . TYR E 1 184 ? 43.711 -57.702 70.369 1.00 136.02 ? 184 TYR E CA 1 +ATOM 9012 C C . TYR E 1 184 ? 42.448 -58.519 70.086 1.00 150.75 ? 184 TYR E C 1 +ATOM 9013 O O . TYR E 1 184 ? 41.311 -58.062 70.269 1.00 92.37 ? 184 TYR E O 1 +ATOM 9014 C CB . TYR E 1 184 ? 44.306 -58.078 71.732 1.00 116.65 ? 184 TYR E CB 1 +ATOM 9015 C CG . TYR E 1 184 ? 43.466 -57.650 72.913 1.00 123.61 ? 184 TYR E CG 1 +ATOM 9016 C CD1 . TYR E 1 184 ? 42.437 -58.455 73.384 1.00 156.73 ? 184 TYR E CD1 1 +ATOM 9017 C CD2 . TYR E 1 184 ? 43.724 -56.459 73.585 1.00 102.48 ? 184 TYR E CD2 1 +ATOM 9018 C CE1 . TYR E 1 184 ? 41.686 -58.073 74.482 1.00 142.74 ? 184 TYR E CE1 1 +ATOM 9019 C CE2 . TYR E 1 184 ? 42.984 -56.074 74.689 1.00 94.18 ? 184 TYR E CE2 1 +ATOM 9020 C CZ . TYR E 1 184 ? 41.966 -56.878 75.128 1.00 118.95 ? 184 TYR E CZ 1 +ATOM 9021 O OH . TYR E 1 184 ? 41.210 -56.484 76.194 1.00 126.60 ? 184 TYR E OH 1 +ATOM 9022 N N . GLU E 1 185 ? 42.682 -59.751 69.644 1.00 194.16 ? 185 GLU E N 1 +ATOM 9023 C CA . GLU E 1 185 ? 41.600 -60.666 69.220 1.00 201.17 ? 185 GLU E CA 1 +ATOM 9024 C C . GLU E 1 185 ? 41.837 -62.073 69.804 1.00 232.65 ? 185 GLU E C 1 +ATOM 9025 O O . GLU E 1 185 ? 42.823 -62.739 69.496 1.00 268.98 ? 185 GLU E O 1 +ATOM 9026 C CB . GLU E 1 185 ? 41.414 -60.614 67.680 1.00 156.78 ? 185 GLU E CB 1 +ATOM 9027 C CG . GLU E 1 185 ? 42.753 -60.600 66.956 1.00 141.58 ? 185 GLU E CG 1 +ATOM 9028 C CD . GLU E 1 185 ? 42.819 -59.738 65.702 1.00 139.28 ? 185 GLU E CD 1 +ATOM 9029 O OE1 . GLU E 1 185 ? 42.499 -58.568 65.882 1.00 117.54 ? 185 GLU E OE1 1 +ATOM 9030 O OE2 . GLU E 1 185 ? 43.355 -60.118 64.609 1.00 164.43 ? 185 GLU E OE2 1 +ATOM 9031 N N . VAL E 1 186 ? 40.998 -62.443 70.773 1.00 204.15 ? 186 VAL E N 1 +ATOM 9032 C CA . VAL E 1 186 ? 41.055 -63.746 71.415 1.00 191.28 ? 186 VAL E CA 1 +ATOM 9033 C C . VAL E 1 186 ? 39.983 -64.653 70.816 1.00 212.35 ? 186 VAL E C 1 +ATOM 9034 O O . VAL E 1 186 ? 38.861 -64.216 70.572 1.00 208.25 ? 186 VAL E O 1 +ATOM 9035 C CB . VAL E 1 186 ? 40.837 -63.631 72.938 1.00 180.78 ? 186 VAL E CB 1 +ATOM 9036 C CG1 . VAL E 1 186 ? 41.092 -64.968 73.610 1.00 200.58 ? 186 VAL E CG1 1 +ATOM 9037 C CG2 . VAL E 1 186 ? 41.749 -62.568 73.532 1.00 195.44 ? 186 VAL E CG2 1 +ATOM 9038 N N . GLN E 1 187 ? 40.341 -65.909 70.560 1.00 227.07 ? 187 GLN E N 1 +ATOM 9039 C CA . GLN E 1 187 ? 39.429 -66.845 69.904 1.00 210.99 ? 187 GLN E CA 1 +ATOM 9040 C C . GLN E 1 187 ? 39.658 -68.269 70.384 1.00 198.78 ? 187 GLN E C 1 +ATOM 9041 O O . GLN E 1 187 ? 40.801 -68.705 70.523 1.00 184.83 ? 187 GLN E O 1 +ATOM 9042 C CB . GLN E 1 187 ? 39.642 -66.797 68.385 1.00 206.26 ? 187 GLN E CB 1 +ATOM 9043 C CG . GLN E 1 187 ? 38.864 -65.725 67.634 1.00 210.69 ? 187 GLN E CG 1 +ATOM 9044 C CD . GLN E 1 187 ? 39.421 -65.496 66.219 1.00 225.19 ? 187 GLN E CD 1 +ATOM 9045 O OE1 . GLN E 1 187 ? 39.121 -64.494 65.540 1.00 243.97 ? 187 GLN E OE1 1 +ATOM 9046 N NE2 . GLN E 1 187 ? 40.214 -66.458 65.751 1.00 196.18 ? 187 GLN E NE2 1 +ATOM 9047 N N . ALA E 1 188 ? 38.568 -68.997 70.604 1.00 198.18 ? 188 ALA E N 1 +ATOM 9048 C CA . ALA E 1 188 ? 38.657 -70.407 70.965 1.00 209.96 ? 188 ALA E CA 1 +ATOM 9049 C C . ALA E 1 188 ? 37.556 -71.207 70.277 1.00 208.06 ? 188 ALA E C 1 +ATOM 9050 O O . ALA E 1 188 ? 36.434 -70.734 70.158 1.00 198.96 ? 188 ALA E O 1 +ATOM 9051 C CB . ALA E 1 188 ? 38.586 -70.568 72.477 1.00 205.36 ? 188 ALA E CB 1 +ATOM 9052 N N . GLY E 1 189 ? 37.888 -72.404 69.802 1.00 189.39 ? 189 GLY E N 1 +ATOM 9053 C CA . GLY E 1 189 ? 36.928 -73.243 69.097 1.00 190.48 ? 189 GLY E CA 1 +ATOM 9054 C C . GLY E 1 189 ? 37.115 -74.725 69.361 1.00 206.34 ? 189 GLY E C 1 +ATOM 9055 O O . GLY E 1 189 ? 38.239 -75.215 69.426 1.00 193.59 ? 189 GLY E O 1 +ATOM 9056 N N . VAL E 1 190 ? 36.005 -75.438 69.534 1.00 239.19 ? 190 VAL E N 1 +ATOM 9057 C CA . VAL E 1 190 ? 36.034 -76.887 69.732 1.00 238.47 ? 190 VAL E CA 1 +ATOM 9058 C C . VAL E 1 190 ? 35.366 -77.587 68.542 1.00 242.31 ? 190 VAL E C 1 +ATOM 9059 O O . VAL E 1 190 ? 34.318 -77.144 68.064 1.00 248.20 ? 190 VAL E O 1 +ATOM 9060 C CB . VAL E 1 190 ? 35.325 -77.288 71.041 1.00 212.96 ? 190 VAL E CB 1 +ATOM 9061 C CG1 . VAL E 1 190 ? 35.589 -78.751 71.350 1.00 213.32 ? 190 VAL E CG1 1 +ATOM 9062 C CG2 . VAL E 1 190 ? 35.776 -76.395 72.196 1.00 194.59 ? 190 VAL E CG2 1 +ATOM 9063 N N . PHE E 1 191 ? 35.996 -78.649 68.038 1.00 231.06 ? 191 PHE E N 1 +ATOM 9064 C CA . PHE E 1 191 ? 35.571 -79.264 66.776 1.00 225.85 ? 191 PHE E CA 1 +ATOM 9065 C C . PHE E 1 191 ? 35.488 -80.779 66.920 1.00 206.28 ? 191 PHE E C 1 +ATOM 9066 O O . PHE E 1 191 ? 36.428 -81.401 67.416 1.00 216.09 ? 191 PHE E O 1 +ATOM 9067 C CB . PHE E 1 191 ? 36.537 -78.869 65.643 1.00 222.32 ? 191 PHE E CB 1 +ATOM 9068 C CG . PHE E 1 191 ? 35.953 -79.000 64.261 1.00 240.93 ? 191 PHE E CG 1 +ATOM 9069 C CD1 . PHE E 1 191 ? 35.749 -80.250 63.697 1.00 237.68 ? 191 PHE E CD1 1 +ATOM 9070 C CD2 . PHE E 1 191 ? 35.633 -77.871 63.511 1.00 229.89 ? 191 PHE E CD2 1 +ATOM 9071 C CE1 . PHE E 1 191 ? 35.225 -80.376 62.421 1.00 211.38 ? 191 PHE E CE1 1 +ATOM 9072 C CE2 . PHE E 1 191 ? 35.097 -77.991 62.241 1.00 210.01 ? 191 PHE E CE2 1 +ATOM 9073 C CZ . PHE E 1 191 ? 34.905 -79.246 61.690 1.00 198.36 ? 191 PHE E CZ 1 +ATOM 9074 N N . LEU E 1 200 ? 30.112 -81.951 65.808 1.00 184.28 ? 200 LEU E N 1 +ATOM 9075 C CA . LEU E 1 200 ? 30.139 -80.889 66.807 1.00 197.54 ? 200 LEU E CA 1 +ATOM 9076 C C . LEU E 1 200 ? 31.178 -79.826 66.467 1.00 205.40 ? 200 LEU E C 1 +ATOM 9077 O O . LEU E 1 200 ? 32.378 -80.103 66.473 1.00 173.26 ? 200 LEU E O 1 +ATOM 9078 C CB . LEU E 1 200 ? 30.460 -81.474 68.181 1.00 186.40 ? 200 LEU E CB 1 +ATOM 9079 C CG . LEU E 1 200 ? 30.739 -80.427 69.275 1.00 174.96 ? 200 LEU E CG 1 +ATOM 9080 C CD1 . LEU E 1 200 ? 29.507 -80.250 70.156 1.00 150.90 ? 200 LEU E CD1 1 +ATOM 9081 C CD2 . LEU E 1 200 ? 31.984 -80.750 70.103 1.00 145.66 ? 200 LEU E CD2 1 +ATOM 9082 N N . GLU E 1 201 ? 30.705 -78.607 66.206 1.00 214.78 ? 201 GLU E N 1 +ATOM 9083 C CA . GLU E 1 201 ? 31.551 -77.420 66.267 1.00 211.96 ? 201 GLU E CA 1 +ATOM 9084 C C . GLU E 1 201 ? 31.015 -76.430 67.295 1.00 207.65 ? 201 GLU E C 1 +ATOM 9085 O O . GLU E 1 201 ? 29.808 -76.343 67.513 1.00 189.50 ? 201 GLU E O 1 +ATOM 9086 C CB . GLU E 1 201 ? 31.639 -76.738 64.903 1.00 209.26 ? 201 GLU E CB 1 +ATOM 9087 C CG . GLU E 1 201 ? 32.841 -75.813 64.779 1.00 208.31 ? 201 GLU E CG 1 +ATOM 9088 C CD . GLU E 1 201 ? 32.938 -75.131 63.425 1.00 195.92 ? 201 GLU E CD 1 +ATOM 9089 O OE1 . GLU E 1 201 ? 32.866 -75.832 62.392 1.00 193.52 ? 201 GLU E OE1 1 +ATOM 9090 O OE2 . GLU E 1 201 ? 33.107 -73.894 63.397 1.00 157.88 ? 201 GLU E OE2 1 +ATOM 9091 N N . GLY E 1 202 ? 31.922 -75.699 67.938 1.00 200.28 ? 202 GLY E N 1 +ATOM 9092 C CA . GLY E 1 202 ? 31.547 -74.625 68.850 1.00 189.30 ? 202 GLY E CA 1 +ATOM 9093 C C . GLY E 1 202 ? 32.647 -73.584 68.937 1.00 172.06 ? 202 GLY E C 1 +ATOM 9094 O O . GLY E 1 202 ? 33.797 -73.910 69.243 1.00 219.97 ? 202 GLY E O 1 +ATOM 9095 N N . GLU E 1 203 ? 32.298 -72.320 68.719 1.00 137.11 ? 203 GLU E N 1 +ATOM 9096 C CA . GLU E 1 203 ? 33.295 -71.249 68.728 1.00 138.68 ? 203 GLU E CA 1 +ATOM 9097 C C . GLU E 1 203 ? 32.921 -70.051 69.610 1.00 151.01 ? 203 GLU E C 1 +ATOM 9098 O O . GLU E 1 203 ? 31.776 -69.595 69.612 1.00 127.09 ? 203 GLU E O 1 +ATOM 9099 C CB . GLU E 1 203 ? 33.547 -70.782 67.304 1.00 144.48 ? 203 GLU E CB 1 +ATOM 9100 C CG . GLU E 1 203 ? 34.210 -71.845 66.436 1.00 143.18 ? 203 GLU E CG 1 +ATOM 9101 C CD . GLU E 1 203 ? 34.566 -71.364 65.036 1.00 180.93 ? 203 GLU E CD 1 +ATOM 9102 O OE1 . GLU E 1 203 ? 34.141 -70.250 64.650 1.00 212.04 ? 203 GLU E OE1 1 +ATOM 9103 O OE2 . GLU E 1 203 ? 35.230 -72.131 64.293 1.00 201.54 ? 203 GLU E OE2 1 +ATOM 9104 N N . VAL E 1 204 ? 33.915 -69.542 70.341 1.00 163.35 ? 204 VAL E N 1 +ATOM 9105 C CA . VAL E 1 204 ? 33.819 -68.276 71.063 1.00 164.58 ? 204 VAL E CA 1 +ATOM 9106 C C . VAL E 1 204 ? 34.924 -67.335 70.577 1.00 170.77 ? 204 VAL E C 1 +ATOM 9107 O O . VAL E 1 204 ? 36.069 -67.749 70.402 1.00 146.80 ? 204 VAL E O 1 +ATOM 9108 C CB . VAL E 1 204 ? 33.927 -68.495 72.589 1.00 148.00 ? 204 VAL E CB 1 +ATOM 9109 C CG1 . VAL E 1 204 ? 34.194 -67.189 73.331 1.00 146.71 ? 204 VAL E CG1 1 +ATOM 9110 C CG2 . VAL E 1 204 ? 32.652 -69.143 73.102 1.00 154.41 ? 204 VAL E CG2 1 +ATOM 9111 N N . GLY E 1 205 ? 34.558 -66.075 70.343 1.00 160.00 ? 205 GLY E N 1 +ATOM 9112 C CA . GLY E 1 205 ? 35.516 -65.053 69.952 1.00 126.90 ? 205 GLY E CA 1 +ATOM 9113 C C . GLY E 1 205 ? 35.295 -63.737 70.691 1.00 133.17 ? 205 GLY E C 1 +ATOM 9114 O O . GLY E 1 205 ? 34.171 -63.407 71.078 1.00 120.80 ? 205 GLY E O 1 +ATOM 9115 N N . TYR E 1 206 ? 36.374 -62.980 70.883 1.00 137.89 ? 206 TYR E N 1 +ATOM 9116 C CA . TYR E 1 206 ? 36.307 -61.622 71.446 1.00 130.93 ? 206 TYR E CA 1 +ATOM 9117 C C . TYR E 1 206 ? 37.407 -60.736 70.866 1.00 149.29 ? 206 TYR E C 1 +ATOM 9118 O O . TYR E 1 206 ? 38.512 -61.200 70.640 1.00 149.82 ? 206 TYR E O 1 +ATOM 9119 C CB . TYR E 1 206 ? 36.464 -61.664 72.958 1.00 113.18 ? 206 TYR E CB 1 +ATOM 9120 C CG . TYR E 1 206 ? 36.476 -60.301 73.619 1.00 94.26 ? 206 TYR E CG 1 +ATOM 9121 C CD1 . TYR E 1 206 ? 35.290 -59.609 73.858 1.00 104.27 ? 206 TYR E CD1 1 +ATOM 9122 C CD2 . TYR E 1 206 ? 37.668 -59.732 74.065 1.00 83.31 ? 206 TYR E CD2 1 +ATOM 9123 C CE1 . TYR E 1 206 ? 35.295 -58.373 74.504 1.00 111.39 ? 206 TYR E CE1 1 +ATOM 9124 C CE2 . TYR E 1 206 ? 37.684 -58.521 74.742 1.00 87.71 ? 206 TYR E CE2 1 +ATOM 9125 C CZ . TYR E 1 206 ? 36.504 -57.824 74.940 1.00 112.41 ? 206 TYR E CZ 1 +ATOM 9126 O OH . TYR E 1 206 ? 36.543 -56.561 75.519 1.00 97.57 ? 206 TYR E OH 1 +ATOM 9127 N N . THR E 1 207 ? 37.088 -59.474 70.584 1.00 153.23 ? 207 THR E N 1 +ATOM 9128 C CA . THR E 1 207 ? 38.074 -58.533 70.040 1.00 145.89 ? 207 THR E CA 1 +ATOM 9129 C C . THR E 1 207 ? 37.942 -57.171 70.716 1.00 159.87 ? 207 THR E C 1 +ATOM 9130 O O . THR E 1 207 ? 36.826 -56.671 70.940 1.00 140.60 ? 207 THR E O 1 +ATOM 9131 C CB . THR E 1 207 ? 37.922 -58.343 68.517 1.00 135.11 ? 207 THR E CB 1 +ATOM 9132 O OG1 . THR E 1 207 ? 36.627 -57.794 68.235 1.00 174.40 ? 207 THR E OG1 1 +ATOM 9133 C CG2 . THR E 1 207 ? 38.070 -59.656 67.789 1.00 130.27 ? 207 THR E CG2 1 +ATOM 9134 N N . SER E 1 208 ? 39.079 -56.572 71.063 1.00 166.30 ? 208 SER E N 1 +ATOM 9135 C CA . SER E 1 208 ? 39.067 -55.256 71.709 1.00 188.87 ? 208 SER E CA 1 +ATOM 9136 C C . SER E 1 208 ? 40.072 -54.288 71.086 1.00 204.36 ? 208 SER E C 1 +ATOM 9137 O O . SER E 1 208 ? 41.257 -54.591 70.987 1.00 152.51 ? 208 SER E O 1 +ATOM 9138 C CB . SER E 1 208 ? 39.328 -55.375 73.213 1.00 187.95 ? 208 SER E CB 1 +ATOM 9139 O OG . SER E 1 208 ? 39.438 -54.088 73.802 1.00 154.32 ? 208 SER E OG 1 +ATOM 9140 N N . ASN E 1 209 ? 39.565 -53.131 70.659 1.00 207.81 ? 209 ASN E N 1 +ATOM 9141 C CA . ASN E 1 209 ? 40.387 -52.035 70.152 1.00 146.87 ? 209 ASN E CA 1 +ATOM 9142 C C . ASN E 1 209 ? 40.308 -50.857 71.089 1.00 167.43 ? 209 ASN E C 1 +ATOM 9143 O O . ASN E 1 209 ? 39.227 -50.488 71.551 1.00 188.08 ? 209 ASN E O 1 +ATOM 9144 C CB . ASN E 1 209 ? 39.892 -51.575 68.794 1.00 116.50 ? 209 ASN E CB 1 +ATOM 9145 C CG . ASN E 1 209 ? 40.155 -52.589 67.724 1.00 110.95 ? 209 ASN E CG 1 +ATOM 9146 O OD1 . ASN E 1 209 ? 41.236 -52.635 67.153 1.00 83.56 ? 209 ASN E OD1 1 +ATOM 9147 N ND2 . ASN E 1 209 ? 39.130 -53.365 67.390 1.00 120.73 ? 209 ASN E ND2 1 +ATOM 9148 N N . GLU E 1 210 ? 41.451 -50.246 71.348 1.00 165.56 ? 210 GLU E N 1 +ATOM 9149 C CA . GLU E 1 210 ? 41.451 -48.949 72.001 1.00 148.00 ? 210 GLU E CA 1 +ATOM 9150 C C . GLU E 1 210 ? 40.852 -47.924 71.043 1.00 109.82 ? 210 GLU E C 1 +ATOM 9151 O O . GLU E 1 210 ? 41.094 -47.976 69.835 1.00 110.04 ? 210 GLU E O 1 +ATOM 9152 C CB . GLU E 1 210 ? 42.885 -48.553 72.380 1.00 217.26 ? 210 GLU E CB 1 +ATOM 9153 C CG . GLU E 1 210 ? 43.043 -47.973 73.777 1.00 237.31 ? 210 GLU E CG 1 +ATOM 9154 C CD . GLU E 1 210 ? 44.492 -47.997 74.262 1.00 218.28 ? 210 GLU E CD 1 +ATOM 9155 O OE1 . GLU E 1 210 ? 45.307 -48.853 73.809 1.00 112.49 ? 210 GLU E OE1 1 +ATOM 9156 O OE2 . GLU E 1 210 ? 44.806 -47.136 75.107 1.00 234.68 ? 210 GLU E OE2 1 +ATOM 9157 N N . PRO E 1 211 ? 40.066 -46.994 71.567 1.00 96.88 ? 211 PRO E N 1 +ATOM 9158 C CA . PRO E 1 211 ? 39.639 -45.881 70.740 1.00 111.94 ? 211 PRO E CA 1 +ATOM 9159 C C . PRO E 1 211 ? 40.771 -44.890 70.445 1.00 113.86 ? 211 PRO E C 1 +ATOM 9160 O O . PRO E 1 211 ? 41.425 -44.396 71.365 1.00 95.81 ? 211 PRO E O 1 +ATOM 9161 C CB . PRO E 1 211 ? 38.545 -45.214 71.577 1.00 114.33 ? 211 PRO E CB 1 +ATOM 9162 C CG . PRO E 1 211 ? 38.152 -46.226 72.587 1.00 123.02 ? 211 PRO E CG 1 +ATOM 9163 C CD . PRO E 1 211 ? 39.415 -46.976 72.874 1.00 118.35 ? 211 PRO E CD 1 +ATOM 9164 N N . VAL E 1 212 ? 41.020 -44.645 69.153 1.00 116.77 ? 212 VAL E N 1 +ATOM 9165 C CA . VAL E 1 212 ? 42.055 -43.703 68.699 1.00 85.46 ? 212 VAL E CA 1 +ATOM 9166 C C . VAL E 1 212 ? 41.693 -42.300 69.160 1.00 75.44 ? 212 VAL E C 1 +ATOM 9167 O O . VAL E 1 212 ? 42.531 -41.553 69.675 1.00 95.81 ? 212 VAL E O 1 +ATOM 9168 C CB . VAL E 1 212 ? 42.181 -43.676 67.168 1.00 78.97 ? 212 VAL E CB 1 +ATOM 9169 C CG1 . VAL E 1 212 ? 43.342 -42.784 66.756 1.00 93.96 ? 212 VAL E CG1 1 +ATOM 9170 C CG2 . VAL E 1 212 ? 42.356 -45.089 66.594 1.00 73.88 ? 212 VAL E CG2 1 +ATOM 9171 N N . MET E 1 213 ? 40.416 -42.004 69.035 1.00 67.39 ? 213 MET E N 1 +ATOM 9172 C CA . MET E 1 213 ? 39.756 -40.918 69.728 1.00 99.52 ? 213 MET E CA 1 +ATOM 9173 C C . MET E 1 213 ? 40.314 -40.645 71.146 1.00 124.34 ? 213 MET E C 1 +ATOM 9174 O O . MET E 1 213 ? 40.640 -39.488 71.513 1.00 177.84 ? 213 MET E O 1 +ATOM 9175 C CB . MET E 1 213 ? 38.271 -41.322 69.795 1.00 106.42 ? 213 MET E CB 1 +ATOM 9176 C CG . MET E 1 213 ? 37.272 -40.321 70.338 1.00 116.37 ? 213 MET E CG 1 +ATOM 9177 S SD . MET E 1 213 ? 35.637 -41.069 70.226 1.00 100.48 ? 213 MET E SD 1 +ATOM 9178 C CE . MET E 1 213 ? 35.404 -41.331 71.977 1.00 148.29 ? 213 MET E CE 1 +ATOM 9179 N N . LEU E 1 214 ? 40.373 -41.700 71.952 1.00 106.31 ? 214 LEU E N 1 +ATOM 9180 C CA . LEU E 1 214 ? 40.552 -41.567 73.394 1.00 118.08 ? 214 LEU E CA 1 +ATOM 9181 C C . LEU E 1 214 ? 42.039 -41.444 73.679 1.00 87.60 ? 214 LEU E C 1 +ATOM 9182 O O . LEU E 1 214 ? 42.451 -40.819 74.659 1.00 91.19 ? 214 LEU E O 1 +ATOM 9183 C CB . LEU E 1 214 ? 39.940 -42.780 74.121 1.00 119.57 ? 214 LEU E CB 1 +ATOM 9184 C CG . LEU E 1 214 ? 39.150 -42.563 75.431 1.00 106.19 ? 214 LEU E CG 1 +ATOM 9185 C CD1 . LEU E 1 214 ? 37.942 -41.656 75.228 1.00 96.03 ? 214 LEU E CD1 1 +ATOM 9186 C CD2 . LEU E 1 214 ? 38.709 -43.912 75.986 1.00 108.68 ? 214 LEU E CD2 1 +ATOM 9187 N N . CYS E 1 215 ? 42.835 -42.051 72.816 1.00 65.93 ? 215 CYS E N 1 +ATOM 9188 C CA . CYS E 1 215 ? 44.287 -41.964 72.919 1.00 87.46 ? 215 CYS E CA 1 +ATOM 9189 C C . CYS E 1 215 ? 44.768 -40.556 72.559 1.00 114.13 ? 215 CYS E C 1 +ATOM 9190 O O . CYS E 1 215 ? 45.712 -40.005 73.177 1.00 107.84 ? 215 CYS E O 1 +ATOM 9191 C CB . CYS E 1 215 ? 44.956 -42.971 71.977 1.00 79.42 ? 215 CYS E CB 1 +ATOM 9192 S SG . CYS E 1 215 ? 44.611 -44.669 72.411 1.00 120.08 ? 215 CYS E SG 1 +ATOM 9193 N N . LEU E 1 216 ? 44.151 -40.005 71.514 1.00 125.75 ? 216 LEU E N 1 +ATOM 9194 C CA . LEU E 1 216 ? 44.430 -38.645 71.106 1.00 121.32 ? 216 LEU E CA 1 +ATOM 9195 C C . LEU E 1 216 ? 44.157 -37.719 72.303 1.00 104.00 ? 216 LEU E C 1 +ATOM 9196 O O . LEU E 1 216 ? 45.011 -36.886 72.650 1.00 140.99 ? 216 LEU E O 1 +ATOM 9197 C CB . LEU E 1 216 ? 43.584 -38.254 69.879 1.00 89.79 ? 216 LEU E CB 1 +ATOM 9198 C CG . LEU E 1 216 ? 43.772 -36.811 69.408 1.00 86.36 ? 216 LEU E CG 1 +ATOM 9199 C CD1 . LEU E 1 216 ? 45.226 -36.477 69.047 1.00 93.73 ? 216 LEU E CD1 1 +ATOM 9200 C CD2 . LEU E 1 216 ? 42.896 -36.532 68.227 1.00 80.32 ? 216 LEU E CD2 1 +ATOM 9201 N N . MET E 1 217 ? 43.006 -37.907 72.942 1.00 59.27 ? 217 MET E N 1 +ATOM 9202 C CA . MET E 1 217 ? 42.605 -37.027 74.009 1.00 53.82 ? 217 MET E CA 1 +ATOM 9203 C C . MET E 1 217 ? 43.586 -37.130 75.152 1.00 69.42 ? 217 MET E C 1 +ATOM 9204 O O . MET E 1 217 ? 44.049 -36.124 75.684 1.00 76.61 ? 217 MET E O 1 +ATOM 9205 C CB . MET E 1 217 ? 41.203 -37.377 74.467 1.00 67.02 ? 217 MET E CB 1 +ATOM 9206 C CG . MET E 1 217 ? 40.330 -36.152 74.715 1.00 91.71 ? 217 MET E CG 1 +ATOM 9207 S SD . MET E 1 217 ? 40.849 -35.215 76.169 1.00 113.64 ? 217 MET E SD 1 +ATOM 9208 C CE . MET E 1 217 ? 39.866 -33.712 76.053 1.00 116.16 ? 217 MET E CE 1 +ATOM 9209 N N . SER E 1 218 ? 43.954 -38.365 75.512 1.00 118.98 ? 218 SER E N 1 +ATOM 9210 C CA . SER E 1 218 ? 44.927 -38.647 76.614 1.00 93.86 ? 218 SER E CA 1 +ATOM 9211 C C . SER E 1 218 ? 46.273 -37.998 76.380 1.00 81.90 ? 218 SER E C 1 +ATOM 9212 O O . SER E 1 218 ? 46.749 -37.227 77.233 1.00 91.09 ? 218 SER E O 1 +ATOM 9213 C CB . SER E 1 218 ? 45.164 -40.139 76.737 1.00 85.11 ? 218 SER E CB 1 +ATOM 9214 O OG . SER E 1 218 ? 45.899 -40.427 77.894 1.00 87.87 ? 218 SER E OG 1 +ATOM 9215 N N . ALA E 1 219 ? 46.806 -38.196 75.170 1.00 78.81 ? 219 ALA E N 1 +ATOM 9216 C CA . ALA E 1 219 ? 48.072 -37.582 74.795 1.00 99.29 ? 219 ALA E CA 1 +ATOM 9217 C C . ALA E 1 219 ? 48.067 -36.016 74.817 1.00 103.70 ? 219 ALA E C 1 +ATOM 9218 O O . ALA E 1 219 ? 49.061 -35.376 75.224 1.00 73.63 ? 219 ALA E O 1 +ATOM 9219 C CB . ALA E 1 219 ? 48.502 -38.090 73.435 1.00 90.28 ? 219 ALA E CB 1 +ATOM 9220 N N . ILE E 1 220 ? 46.955 -35.406 74.411 1.00 84.64 ? 220 ILE E N 1 +ATOM 9221 C CA . ILE E 1 220 ? 46.837 -33.955 74.452 1.00 89.02 ? 220 ILE E CA 1 +ATOM 9222 C C . ILE E 1 220 ? 46.828 -33.423 75.894 1.00 121.62 ? 220 ILE E C 1 +ATOM 9223 O O . ILE E 1 220 ? 47.490 -32.426 76.209 1.00 146.39 ? 220 ILE E O 1 +ATOM 9224 C CB . ILE E 1 220 ? 45.584 -33.478 73.723 1.00 93.27 ? 220 ILE E CB 1 +ATOM 9225 C CG1 . ILE E 1 220 ? 45.755 -33.724 72.219 1.00 118.79 ? 220 ILE E CG1 1 +ATOM 9226 C CG2 . ILE E 1 220 ? 45.309 -31.999 74.012 1.00 80.75 ? 220 ILE E CG2 1 +ATOM 9227 C CD1 . ILE E 1 220 ? 44.459 -33.662 71.428 1.00 162.84 ? 220 ILE E CD1 1 +ATOM 9228 N N . GLU E 1 221 ? 46.127 -34.117 76.785 1.00 154.84 ? 221 GLU E N 1 +ATOM 9229 C CA . GLU E 1 221 ? 46.137 -33.774 78.218 1.00 152.16 ? 221 GLU E CA 1 +ATOM 9230 C C . GLU E 1 221 ? 47.559 -33.796 78.778 1.00 121.13 ? 221 GLU E C 1 +ATOM 9231 O O . GLU E 1 221 ? 48.018 -32.825 79.395 1.00 103.49 ? 221 GLU E O 1 +ATOM 9232 C CB . GLU E 1 221 ? 45.252 -34.752 79.013 1.00 168.87 ? 221 GLU E CB 1 +ATOM 9233 C CG . GLU E 1 221 ? 43.762 -34.535 78.810 1.00 182.16 ? 221 GLU E CG 1 +ATOM 9234 C CD . GLU E 1 221 ? 42.916 -35.715 79.270 1.00 159.47 ? 221 GLU E CD 1 +ATOM 9235 O OE1 . GLU E 1 221 ? 43.316 -36.890 79.050 1.00 128.04 ? 221 GLU E OE1 1 +ATOM 9236 O OE2 . GLU E 1 221 ? 41.782 -35.448 79.718 1.00 137.73 ? 221 GLU E OE2 1 +ATOM 9237 N N . THR E 1 222 ? 48.245 -34.913 78.539 1.00 98.07 ? 222 THR E N 1 +ATOM 9238 C CA . THR E 1 222 ? 49.640 -35.098 78.932 1.00 94.40 ? 222 THR E CA 1 +ATOM 9239 C C . THR E 1 222 ? 50.506 -33.930 78.454 1.00 112.45 ? 222 THR E C 1 +ATOM 9240 O O . THR E 1 222 ? 51.300 -33.382 79.231 1.00 101.06 ? 222 THR E O 1 +ATOM 9241 C CB . THR E 1 222 ? 50.199 -36.400 78.328 1.00 89.00 ? 222 THR E CB 1 +ATOM 9242 O OG1 . THR E 1 222 ? 49.602 -37.534 78.986 1.00 93.55 ? 222 THR E OG1 1 +ATOM 9243 C CG2 . THR E 1 222 ? 51.736 -36.452 78.415 1.00 91.62 ? 222 THR E CG2 1 +ATOM 9244 N N . GLY E 1 223 ? 50.365 -33.581 77.172 1.00 105.45 ? 223 GLY E N 1 +ATOM 9245 C CA . GLY E 1 223 ? 51.074 -32.442 76.593 1.00 97.79 ? 223 GLY E CA 1 +ATOM 9246 C C . GLY E 1 223 ? 50.803 -31.158 77.359 1.00 99.40 ? 223 GLY E C 1 +ATOM 9247 O O . GLY E 1 223 ? 51.709 -30.341 77.566 1.00 109.35 ? 223 GLY E O 1 +ATOM 9248 N N . VAL E 1 224 ? 49.549 -30.954 77.769 1.00 103.47 ? 224 VAL E N 1 +ATOM 9249 C CA . VAL E 1 224 ? 49.177 -29.732 78.486 1.00 115.14 ? 224 VAL E CA 1 +ATOM 9250 C C . VAL E 1 224 ? 49.903 -29.682 79.824 1.00 115.71 ? 224 VAL E C 1 +ATOM 9251 O O . VAL E 1 224 ? 50.416 -28.630 80.216 1.00 112.51 ? 224 VAL E O 1 +ATOM 9252 C CB . VAL E 1 224 ? 47.656 -29.630 78.722 1.00 118.31 ? 224 VAL E CB 1 +ATOM 9253 C CG1 . VAL E 1 224 ? 47.341 -28.446 79.633 1.00 101.63 ? 224 VAL E CG1 1 +ATOM 9254 C CG2 . VAL E 1 224 ? 46.914 -29.506 77.390 1.00 113.34 ? 224 VAL E CG2 1 +ATOM 9255 N N . ILE E 1 225 ? 49.975 -30.824 80.502 1.00 111.45 ? 225 ILE E N 1 +ATOM 9256 C CA . ILE E 1 225 ? 50.690 -30.893 81.765 1.00 114.33 ? 225 ILE E CA 1 +ATOM 9257 C C . ILE E 1 225 ? 52.165 -30.537 81.565 1.00 130.32 ? 225 ILE E C 1 +ATOM 9258 O O . ILE E 1 225 ? 52.670 -29.653 82.267 1.00 139.57 ? 225 ILE E O 1 +ATOM 9259 C CB . ILE E 1 225 ? 50.571 -32.270 82.428 1.00 117.80 ? 225 ILE E CB 1 +ATOM 9260 C CG1 . ILE E 1 225 ? 49.131 -32.518 82.888 1.00 116.70 ? 225 ILE E CG1 1 +ATOM 9261 C CG2 . ILE E 1 225 ? 51.495 -32.362 83.634 1.00 136.93 ? 225 ILE E CG2 1 +ATOM 9262 C CD1 . ILE E 1 225 ? 48.824 -33.979 83.158 1.00 133.36 ? 225 ILE E CD1 1 +ATOM 9263 N N . PHE E 1 226 ? 52.836 -31.194 80.608 1.00 121.82 ? 226 PHE E N 1 +ATOM 9264 C CA . PHE E 1 226 ? 54.260 -30.910 80.307 1.00 114.64 ? 226 PHE E CA 1 +ATOM 9265 C C . PHE E 1 226 ? 54.494 -29.444 79.948 1.00 121.68 ? 226 PHE E C 1 +ATOM 9266 O O . PHE E 1 226 ? 55.516 -28.862 80.303 1.00 123.07 ? 226 PHE E O 1 +ATOM 9267 C CB . PHE E 1 226 ? 54.779 -31.769 79.159 1.00 105.28 ? 226 PHE E CB 1 +ATOM 9268 C CG . PHE E 1 226 ? 55.145 -33.190 79.561 1.00 134.08 ? 226 PHE E CG 1 +ATOM 9269 C CD1 . PHE E 1 226 ? 56.138 -33.430 80.505 1.00 140.35 ? 226 PHE E CD1 1 +ATOM 9270 C CD2 . PHE E 1 226 ? 54.561 -34.296 78.919 1.00 124.51 ? 226 PHE E CD2 1 +ATOM 9271 C CE1 . PHE E 1 226 ? 56.513 -34.733 80.824 1.00 125.96 ? 226 PHE E CE1 1 +ATOM 9272 C CE2 . PHE E 1 226 ? 54.957 -35.600 79.205 1.00 83.28 ? 226 PHE E CE2 1 +ATOM 9273 C CZ . PHE E 1 226 ? 55.901 -35.818 80.188 1.00 112.10 ? 226 PHE E CZ 1 +ATOM 9274 N N . LEU E 1 227 ? 53.506 -28.825 79.312 1.00 128.49 ? 227 LEU E N 1 +ATOM 9275 C CA . LEU E 1 227 ? 53.565 -27.395 79.023 1.00 129.13 ? 227 LEU E CA 1 +ATOM 9276 C C . LEU E 1 227 ? 53.513 -26.552 80.297 1.00 120.35 ? 227 LEU E C 1 +ATOM 9277 O O . LEU E 1 227 ? 54.271 -25.591 80.422 1.00 145.59 ? 227 LEU E O 1 +ATOM 9278 C CB . LEU E 1 227 ? 52.418 -27.010 78.083 1.00 137.42 ? 227 LEU E CB 1 +ATOM 9279 C CG . LEU E 1 227 ? 52.606 -27.387 76.606 1.00 126.96 ? 227 LEU E CG 1 +ATOM 9280 C CD1 . LEU E 1 227 ? 51.352 -27.284 75.754 1.00 120.88 ? 227 LEU E CD1 1 +ATOM 9281 C CD2 . LEU E 1 227 ? 53.719 -26.601 75.951 1.00 105.89 ? 227 LEU E CD2 1 +ATOM 9282 N N . ILE E 1 228 ? 52.615 -26.897 81.221 1.00 90.11 ? 228 ILE E N 1 +ATOM 9283 C CA . ILE E 1 228 ? 52.441 -26.112 82.447 1.00 91.97 ? 228 ILE E CA 1 +ATOM 9284 C C . ILE E 1 228 ? 53.691 -26.240 83.295 1.00 96.18 ? 228 ILE E C 1 +ATOM 9285 O O . ILE E 1 228 ? 54.238 -25.244 83.768 1.00 87.01 ? 228 ILE E O 1 +ATOM 9286 C CB . ILE E 1 228 ? 51.228 -26.563 83.287 1.00 91.52 ? 228 ILE E CB 1 +ATOM 9287 C CG1 . ILE E 1 228 ? 49.913 -26.310 82.536 1.00 115.04 ? 228 ILE E CG1 1 +ATOM 9288 C CG2 . ILE E 1 228 ? 51.182 -25.801 84.599 1.00 72.63 ? 228 ILE E CG2 1 +ATOM 9289 C CD1 . ILE E 1 228 ? 48.713 -27.046 83.102 1.00 111.06 ? 228 ILE E CD1 1 +ATOM 9290 N N . ASN E 1 229 ? 54.159 -27.472 83.449 1.00 108.75 ? 229 ASN E N 1 +ATOM 9291 C CA . ASN E 1 229 ? 55.365 -27.745 84.229 1.00 118.36 ? 229 ASN E CA 1 +ATOM 9292 C C . ASN E 1 229 ? 56.588 -27.030 83.650 1.00 105.95 ? 229 ASN E C 1 +ATOM 9293 O O . ASN E 1 229 ? 57.339 -26.385 84.379 1.00 116.92 ? 229 ASN E O 1 +ATOM 9294 C CB . ASN E 1 229 ? 55.625 -29.253 84.276 1.00 138.15 ? 229 ASN E CB 1 +ATOM 9295 C CG . ASN E 1 229 ? 56.600 -29.642 85.362 1.00 150.82 ? 229 ASN E CG 1 +ATOM 9296 O OD1 . ASN E 1 229 ? 56.745 -28.939 86.369 1.00 179.44 ? 229 ASN E OD1 1 +ATOM 9297 N ND2 . ASN E 1 229 ? 57.224 -30.803 85.198 1.00 149.94 ? 229 ASN E ND2 1 +ATOM 9298 N N . ASP E 1 230 ? 56.739 -27.103 82.329 1.00 93.79 ? 230 ASP E N 1 +ATOM 9299 C CA . ASP E 1 230 ? 57.801 -26.399 81.629 1.00 75.49 ? 230 ASP E CA 1 +ATOM 9300 C C . ASP E 1 230 ? 57.701 -24.877 81.861 1.00 90.71 ? 230 ASP E C 1 +ATOM 9301 O O . ASP E 1 230 ? 58.711 -24.205 82.077 1.00 87.19 ? 230 ASP E O 1 +ATOM 9302 C CB . ASP E 1 230 ? 57.743 -26.686 80.136 1.00 73.23 ? 230 ASP E CB 1 +ATOM 9303 C CG . ASP E 1 230 ? 58.923 -26.083 79.385 1.00 74.80 ? 230 ASP E CG 1 +ATOM 9304 O OD1 . ASP E 1 230 ? 60.001 -26.646 79.510 1.00 70.36 ? 230 ASP E OD1 1 +ATOM 9305 O OD2 . ASP E 1 230 ? 58.732 -25.105 78.610 1.00 108.21 ? 230 ASP E OD2 1 +ATOM 9306 N N . GLY E 1 231 ? 56.479 -24.339 81.834 1.00 87.18 ? 231 GLY E N 1 +ATOM 9307 C CA . GLY E 1 231 ? 56.269 -22.913 82.031 1.00 94.69 ? 231 GLY E CA 1 +ATOM 9308 C C . GLY E 1 231 ? 56.567 -22.487 83.457 1.00 110.35 ? 231 GLY E C 1 +ATOM 9309 O O . GLY E 1 231 ? 57.091 -21.375 83.695 1.00 163.07 ? 231 GLY E O 1 +ATOM 9310 N N . ILE E 1 232 ? 56.264 -23.370 84.409 1.00 104.51 ? 232 ILE E N 1 +ATOM 9311 C CA . ILE E 1 232 ? 56.631 -23.139 85.816 1.00 129.80 ? 232 ILE E CA 1 +ATOM 9312 C C . ILE E 1 232 ? 58.152 -23.014 85.986 1.00 118.82 ? 232 ILE E C 1 +ATOM 9313 O O . ILE E 1 232 ? 58.634 -22.044 86.564 1.00 100.90 ? 232 ILE E O 1 +ATOM 9314 C CB . ILE E 1 232 ? 56.105 -24.267 86.733 1.00 148.13 ? 232 ILE E CB 1 +ATOM 9315 C CG1 . ILE E 1 232 ? 54.588 -24.146 86.877 1.00 143.24 ? 232 ILE E CG1 1 +ATOM 9316 C CG2 . ILE E 1 232 ? 56.778 -24.228 88.105 1.00 148.48 ? 232 ILE E CG2 1 +ATOM 9317 C CD1 . ILE E 1 232 ? 53.923 -25.408 87.378 1.00 174.14 ? 232 ILE E CD1 1 +ATOM 9318 N N . ASP E 1 233 ? 58.889 -23.986 85.454 1.00 108.35 ? 233 ASP E N 1 +ATOM 9319 C CA . ASP E 1 233 ? 60.348 -23.954 85.458 1.00 105.60 ? 233 ASP E CA 1 +ATOM 9320 C C . ASP E 1 233 ? 60.876 -22.665 84.833 1.00 119.97 ? 233 ASP E C 1 +ATOM 9321 O O . ASP E 1 233 ? 61.749 -22.013 85.401 1.00 152.59 ? 233 ASP E O 1 +ATOM 9322 C CB . ASP E 1 233 ? 60.926 -25.166 84.701 1.00 116.37 ? 233 ASP E CB 1 +ATOM 9323 C CG . ASP E 1 233 ? 60.617 -26.501 85.385 1.00 116.27 ? 233 ASP E CG 1 +ATOM 9324 O OD1 . ASP E 1 233 ? 59.770 -26.532 86.304 1.00 127.91 ? 233 ASP E OD1 1 +ATOM 9325 O OD2 . ASP E 1 233 ? 61.156 -27.533 84.933 1.00 97.80 ? 233 ASP E OD2 1 +ATOM 9326 N N . ARG E 1 234 ? 60.380 -22.317 83.645 1.00 158.65 ? 234 ARG E N 1 +ATOM 9327 C CA . ARG E 1 234 ? 60.938 -21.199 82.867 1.00 182.88 ? 234 ARG E CA 1 +ATOM 9328 C C . ARG E 1 234 ? 60.431 -19.825 83.299 1.00 152.14 ? 234 ARG E C 1 +ATOM 9329 O O . ARG E 1 234 ? 60.858 -18.805 82.758 1.00 136.13 ? 234 ARG E O 1 +ATOM 9330 C CB . ARG E 1 234 ? 60.662 -21.403 81.377 1.00 200.67 ? 234 ARG E CB 1 +ATOM 9331 C CG . ARG E 1 234 ? 61.525 -22.501 80.782 1.00 203.71 ? 234 ARG E CG 1 +ATOM 9332 C CD . ARG E 1 234 ? 60.936 -23.082 79.501 1.00 175.17 ? 234 ARG E CD 1 +ATOM 9333 N NE . ARG E 1 234 ? 61.748 -24.199 79.032 1.00 156.13 ? 234 ARG E NE 1 +ATOM 9334 C CZ . ARG E 1 234 ? 62.366 -24.242 77.857 1.00 152.28 ? 234 ARG E CZ 1 +ATOM 9335 N NH1 . ARG E 1 234 ? 62.150 -23.278 76.964 1.00 157.39 ? 234 ARG E NH1 1 +ATOM 9336 N NH2 . ARG E 1 234 ? 63.230 -25.222 77.582 1.00 119.37 ? 234 ARG E NH2 1 +ATOM 9337 N N . GLY E 1 235 ? 59.553 -19.798 84.298 1.00 138.29 ? 235 GLY E N 1 +ATOM 9338 C CA . GLY E 1 235 ? 59.080 -18.541 84.866 1.00 117.72 ? 235 GLY E CA 1 +ATOM 9339 C C . GLY E 1 235 ? 58.069 -17.837 83.984 1.00 94.82 ? 235 GLY E C 1 +ATOM 9340 O O . GLY E 1 235 ? 58.019 -16.605 83.957 1.00 75.45 ? 235 GLY E O 1 +ATOM 9341 N N . LEU E 1 236 ? 57.265 -18.604 83.256 1.00 101.14 ? 236 LEU E N 1 +ATOM 9342 C CA . LEU E 1 236 ? 56.101 -18.020 82.574 1.00 115.28 ? 236 LEU E CA 1 +ATOM 9343 C C . LEU E 1 236 ? 55.028 -17.701 83.606 1.00 110.47 ? 236 LEU E C 1 +ATOM 9344 O O . LEU E 1 236 ? 54.469 -16.607 83.619 1.00 105.32 ? 236 LEU E O 1 +ATOM 9345 C CB . LEU E 1 236 ? 55.530 -18.966 81.504 1.00 140.93 ? 236 LEU E CB 1 +ATOM 9346 C CG . LEU E 1 236 ? 56.195 -18.969 80.116 1.00 165.86 ? 236 LEU E CG 1 +ATOM 9347 C CD1 . LEU E 1 236 ? 57.490 -19.781 80.139 1.00 148.22 ? 236 LEU E CD1 1 +ATOM 9348 C CD2 . LEU E 1 236 ? 55.238 -19.533 79.070 1.00 168.69 ? 236 LEU E CD2 1 +ATOM 9349 N N . TRP E 1 237 ? 54.744 -18.668 84.470 1.00 124.35 ? 237 TRP E N 1 +ATOM 9350 C CA . TRP E 1 237 ? 53.700 -18.514 85.481 1.00 134.33 ? 237 TRP E CA 1 +ATOM 9351 C C . TRP E 1 237 ? 54.162 -19.115 86.810 1.00 149.56 ? 237 TRP E C 1 +ATOM 9352 O O . TRP E 1 237 ? 55.142 -19.877 86.850 1.00 120.40 ? 237 TRP E O 1 +ATOM 9353 C CB . TRP E 1 237 ? 52.396 -19.158 84.998 1.00 122.49 ? 237 TRP E CB 1 +ATOM 9354 C CG . TRP E 1 237 ? 52.622 -20.356 84.131 1.00 130.82 ? 237 TRP E CG 1 +ATOM 9355 C CD1 . TRP E 1 237 ? 53.158 -21.545 84.518 1.00 154.97 ? 237 TRP E CD1 1 +ATOM 9356 C CD2 . TRP E 1 237 ? 52.330 -20.484 82.732 1.00 133.48 ? 237 TRP E CD2 1 +ATOM 9357 N NE1 . TRP E 1 237 ? 53.223 -22.408 83.447 1.00 151.09 ? 237 TRP E NE1 1 +ATOM 9358 C CE2 . TRP E 1 237 ? 52.710 -21.790 82.341 1.00 130.93 ? 237 TRP E CE2 1 +ATOM 9359 C CE3 . TRP E 1 237 ? 51.764 -19.636 81.784 1.00 146.32 ? 237 TRP E CE3 1 +ATOM 9360 C CZ2 . TRP E 1 237 ? 52.575 -22.257 81.032 1.00 119.51 ? 237 TRP E CZ2 1 +ATOM 9361 C CZ3 . TRP E 1 237 ? 51.620 -20.104 80.485 1.00 163.14 ? 237 TRP E CZ3 1 +ATOM 9362 C CH2 . TRP E 1 237 ? 52.018 -21.410 80.125 1.00 145.65 ? 237 TRP E CH2 1 +ATOM 9363 N N . ASP E 1 238 ? 53.454 -18.770 87.888 1.00 155.78 ? 238 ASP E N 1 +ATOM 9364 C CA . ASP E 1 238 ? 53.863 -19.147 89.241 1.00 161.92 ? 238 ASP E CA 1 +ATOM 9365 C C . ASP E 1 238 ? 52.751 -19.810 90.063 1.00 155.15 ? 238 ASP E C 1 +ATOM 9366 O O . ASP E 1 238 ? 51.567 -19.523 89.906 1.00 91.09 ? 238 ASP E O 1 +ATOM 9367 C CB . ASP E 1 238 ? 54.377 -17.934 90.014 1.00 149.90 ? 238 ASP E CB 1 +ATOM 9368 C CG . ASP E 1 238 ? 55.509 -17.227 89.303 1.00 145.26 ? 238 ASP E CG 1 +ATOM 9369 O OD1 . ASP E 1 238 ? 55.220 -16.472 88.361 1.00 140.90 ? 238 ASP E OD1 1 +ATOM 9370 O OD2 . ASP E 1 238 ? 56.682 -17.440 89.668 1.00 163.32 ? 238 ASP E OD2 1 +ATOM 9371 N N . LEU E 1 239 ? 53.171 -20.699 90.957 1.00 149.29 ? 239 LEU E N 1 +ATOM 9372 C CA . LEU E 1 239 ? 52.264 -21.483 91.769 1.00 120.75 ? 239 LEU E CA 1 +ATOM 9373 C C . LEU E 1 239 ? 51.773 -20.668 92.949 1.00 132.18 ? 239 LEU E C 1 +ATOM 9374 O O . LEU E 1 239 ? 52.481 -19.793 93.456 1.00 122.76 ? 239 LEU E O 1 +ATOM 9375 C CB . LEU E 1 239 ? 52.966 -22.781 92.177 1.00 114.12 ? 239 LEU E CB 1 +ATOM 9376 C CG . LEU E 1 239 ? 52.087 -23.933 92.687 1.00 129.86 ? 239 LEU E CG 1 +ATOM 9377 C CD1 . LEU E 1 239 ? 50.902 -24.046 91.740 1.00 129.08 ? 239 LEU E CD1 1 +ATOM 9378 C CD2 . LEU E 1 239 ? 52.886 -25.226 92.676 1.00 134.47 ? 239 LEU E CD2 1 +ATOM 9379 N N . GLN E 1 240 ? 50.503 -20.865 93.298 1.00 147.74 ? 240 GLN E N 1 +ATOM 9380 C CA . GLN E 1 240 ? 49.929 -20.250 94.500 1.00 127.30 ? 240 GLN E CA 1 +ATOM 9381 C C . GLN E 1 240 ? 50.777 -20.597 95.721 1.00 132.29 ? 240 GLN E C 1 +ATOM 9382 O O . GLN E 1 240 ? 51.288 -19.707 96.411 1.00 140.99 ? 240 GLN E O 1 +ATOM 9383 C CB . GLN E 1 240 ? 48.491 -20.734 94.714 1.00 116.34 ? 240 GLN E CB 1 +ATOM 9384 C CG . GLN E 1 240 ? 47.763 -20.004 95.833 1.00 125.35 ? 240 GLN E CG 1 +ATOM 9385 C CD . GLN E 1 240 ? 47.554 -18.533 95.514 1.00 116.07 ? 240 GLN E CD 1 +ATOM 9386 O OE1 . GLN E 1 240 ? 46.622 -18.173 94.794 1.00 116.14 ? 240 GLN E OE1 1 +ATOM 9387 N NE2 . GLN E 1 240 ? 48.429 -17.677 96.038 1.00 115.31 ? 240 GLN E NE2 1 +ATOM 9388 N N . ASN E 1 241 ? 50.961 -21.896 95.933 1.00 137.63 ? 241 ASN E N 1 +ATOM 9389 C CA . ASN E 1 241 ? 51.780 -22.407 97.024 1.00 149.25 ? 241 ASN E CA 1 +ATOM 9390 C C . ASN E 1 241 ? 53.116 -22.914 96.516 1.00 143.71 ? 241 ASN E C 1 +ATOM 9391 O O . ASN E 1 241 ? 53.184 -23.954 95.837 1.00 148.89 ? 241 ASN E O 1 +ATOM 9392 C CB . ASN E 1 241 ? 51.052 -23.551 97.717 1.00 161.11 ? 241 ASN E CB 1 +ATOM 9393 C CG . ASN E 1 241 ? 50.384 -23.119 98.997 1.00 172.92 ? 241 ASN E CG 1 +ATOM 9394 O OD1 . ASN E 1 241 ? 50.907 -23.369 100.079 1.00 189.90 ? 241 ASN E OD1 1 +ATOM 9395 N ND2 . ASN E 1 241 ? 49.240 -22.446 98.886 1.00 163.65 ? 241 ASN E ND2 1 +ATOM 9396 N N . LYS E 1 242 ? 54.181 -22.198 96.866 1.00 126.94 ? 242 LYS E N 1 +ATOM 9397 C CA . LYS E 1 242 ? 55.520 -22.576 96.428 1.00 138.23 ? 242 LYS E CA 1 +ATOM 9398 C C . LYS E 1 242 ? 55.899 -23.901 97.071 1.00 152.98 ? 242 LYS E C 1 +ATOM 9399 O O . LYS E 1 242 ? 56.708 -24.665 96.525 1.00 147.07 ? 242 LYS E O 1 +ATOM 9400 C CB . LYS E 1 242 ? 56.534 -21.480 96.774 1.00 156.24 ? 242 LYS E CB 1 +ATOM 9401 C CG . LYS E 1 242 ? 56.105 -20.079 96.338 1.00 161.80 ? 242 LYS E CG 1 +ATOM 9402 C CD . LYS E 1 242 ? 57.157 -19.397 95.473 1.00 171.22 ? 242 LYS E CD 1 +ATOM 9403 C CE . LYS E 1 242 ? 56.528 -18.761 94.242 1.00 166.30 ? 242 LYS E CE 1 +ATOM 9404 N NZ . LYS E 1 242 ? 57.502 -17.959 93.456 1.00 171.08 ? 242 LYS E NZ 1 +ATOM 9405 N N . ALA E 1 243 ? 55.269 -24.170 98.219 1.00 173.15 ? 243 ALA E N 1 +ATOM 9406 C CA . ALA E 1 243 ? 55.398 -25.438 98.937 1.00 186.17 ? 243 ALA E CA 1 +ATOM 9407 C C . ALA E 1 243 ? 54.879 -26.608 98.106 1.00 203.45 ? 243 ALA E C 1 +ATOM 9408 O O . ALA E 1 243 ? 55.218 -27.765 98.388 1.00 247.48 ? 243 ALA E O 1 +ATOM 9409 C CB . ALA E 1 243 ? 54.647 -25.373 100.263 1.00 156.07 ? 243 ALA E CB 1 +ATOM 9410 N N . GLU E 1 244 ? 54.059 -26.314 97.094 1.00 178.25 ? 244 GLU E N 1 +ATOM 9411 C CA . GLU E 1 244 ? 53.477 -27.373 96.281 1.00 146.39 ? 244 GLU E CA 1 +ATOM 9412 C C . GLU E 1 244 ? 54.308 -27.672 95.037 1.00 130.18 ? 244 GLU E C 1 +ATOM 9413 O O . GLU E 1 244 ? 53.838 -28.398 94.173 1.00 144.55 ? 244 GLU E O 1 +ATOM 9414 C CB . GLU E 1 244 ? 52.042 -27.020 95.883 1.00 135.44 ? 244 GLU E CB 1 +ATOM 9415 C CG . GLU E 1 244 ? 51.038 -27.116 97.025 1.00 130.57 ? 244 GLU E CG 1 +ATOM 9416 C CD . GLU E 1 244 ? 49.595 -27.018 96.557 1.00 141.93 ? 244 GLU E CD 1 +ATOM 9417 O OE1 . GLU E 1 244 ? 49.141 -25.893 96.236 1.00 144.10 ? 244 GLU E OE1 1 +ATOM 9418 O OE2 . GLU E 1 244 ? 48.920 -28.071 96.485 1.00 123.77 ? 244 GLU E OE2 1 +ATOM 9419 N N . ARG E 1 245 ? 55.534 -27.141 94.973 1.00 115.19 ? 245 ARG E N 1 +ATOM 9420 C CA . ARG E 1 245 ? 56.503 -27.478 93.917 1.00 147.40 ? 245 ARG E CA 1 +ATOM 9421 C C . ARG E 1 245 ? 56.747 -28.992 93.790 1.00 136.73 ? 245 ARG E C 1 +ATOM 9422 O O . ARG E 1 245 ? 56.842 -29.540 92.676 1.00 104.01 ? 245 ARG E O 1 +ATOM 9423 C CB . ARG E 1 245 ? 57.856 -26.678 94.129 1.00 189.22 ? 245 ARG E CB 1 +ATOM 9424 C CG . ARG E 1 245 ? 57.777 -25.377 93.356 1.00 197.40 ? 245 ARG E CG 1 +ATOM 9425 C CD . ARG E 1 245 ? 59.113 -24.841 92.942 1.00 196.31 ? 245 ARG E CD 1 +ATOM 9426 N NE . ARG E 1 245 ? 59.199 -24.885 91.486 1.00 181.50 ? 245 ARG E NE 1 +ATOM 9427 C CZ . ARG E 1 245 ? 59.454 -25.971 90.748 1.00 146.87 ? 245 ARG E CZ 1 +ATOM 9428 N NH1 . ARG E 1 245 ? 59.757 -27.131 91.304 1.00 107.58 ? 245 ARG E NH1 1 +ATOM 9429 N NH2 . ARG E 1 245 ? 59.442 -25.875 89.425 1.00 154.10 ? 245 ARG E NH2 1 +ATOM 9430 N N . GLN E 1 246 ? 56.808 -29.677 94.929 1.00 144.27 ? 246 GLN E N 1 +ATOM 9431 C CA . GLN E 1 246 ? 57.121 -31.107 94.938 1.00 146.94 ? 246 GLN E CA 1 +ATOM 9432 C C . GLN E 1 246 ? 55.854 -31.970 94.938 1.00 150.52 ? 246 GLN E C 1 +ATOM 9433 O O . GLN E 1 246 ? 55.888 -33.137 95.324 1.00 174.11 ? 246 GLN E O 1 +ATOM 9434 C CB . GLN E 1 246 ? 58.004 -31.463 96.140 1.00 132.31 ? 246 GLN E CB 1 +ATOM 9435 C CG . GLN E 1 246 ? 59.424 -30.937 96.050 1.00 121.83 ? 246 GLN E CG 1 +ATOM 9436 C CD . GLN E 1 246 ? 59.510 -29.448 96.316 1.00 147.23 ? 246 GLN E CD 1 +ATOM 9437 O OE1 . GLN E 1 246 ? 58.896 -28.935 97.256 1.00 166.37 ? 246 GLN E OE1 1 +ATOM 9438 N NE2 . GLN E 1 246 ? 60.287 -28.745 95.500 1.00 177.18 ? 246 GLN E NE2 1 +ATOM 9439 N N . ASN E 1 247 ? 54.746 -31.392 94.483 1.00 139.32 ? 247 ASN E N 1 +ATOM 9440 C CA . ASN E 1 247 ? 53.530 -32.143 94.160 1.00 136.41 ? 247 ASN E CA 1 +ATOM 9441 C C . ASN E 1 247 ? 53.819 -33.454 93.427 1.00 132.53 ? 247 ASN E C 1 +ATOM 9442 O O . ASN E 1 247 ? 54.676 -33.491 92.537 1.00 150.70 ? 247 ASN E O 1 +ATOM 9443 C CB . ASN E 1 247 ? 52.629 -31.288 93.273 1.00 146.69 ? 247 ASN E CB 1 +ATOM 9444 C CG . ASN E 1 247 ? 51.178 -31.663 93.399 1.00 145.43 ? 247 ASN E CG 1 +ATOM 9445 O OD1 . ASN E 1 247 ? 50.579 -32.210 92.466 1.00 130.46 ? 247 ASN E OD1 1 +ATOM 9446 N ND2 . ASN E 1 247 ? 50.583 -31.317 94.538 1.00 142.21 ? 247 ASN E ND2 1 +ATOM 9447 N N . ASP E 1 248 ? 53.115 -34.521 93.806 1.00 137.43 ? 248 ASP E N 1 +ATOM 9448 C CA . ASP E 1 248 ? 53.355 -35.867 93.242 1.00 166.26 ? 248 ASP E CA 1 +ATOM 9449 C C . ASP E 1 248 ? 53.310 -35.844 91.714 1.00 172.11 ? 248 ASP E C 1 +ATOM 9450 O O . ASP E 1 248 ? 54.166 -36.423 91.034 1.00 153.38 ? 248 ASP E O 1 +ATOM 9451 C CB . ASP E 1 248 ? 52.300 -36.868 93.744 1.00 164.80 ? 248 ASP E CB 1 +ATOM 9452 C CG . ASP E 1 248 ? 52.482 -37.245 95.203 1.00 173.41 ? 248 ASP E CG 1 +ATOM 9453 O OD1 . ASP E 1 248 ? 53.635 -37.386 95.658 1.00 183.28 ? 248 ASP E OD1 1 +ATOM 9454 O OD2 . ASP E 1 248 ? 51.457 -37.402 95.898 1.00 187.78 ? 248 ASP E OD2 1 +ATOM 9455 N N . ILE E 1 249 ? 52.286 -35.180 91.190 1.00 168.28 ? 249 ILE E N 1 +ATOM 9456 C CA . ILE E 1 249 ? 52.046 -35.134 89.760 1.00 159.29 ? 249 ILE E CA 1 +ATOM 9457 C C . ILE E 1 249 ? 53.164 -34.350 89.068 1.00 153.80 ? 249 ILE E C 1 +ATOM 9458 O O . ILE E 1 249 ? 53.772 -34.818 88.100 1.00 162.98 ? 249 ILE E O 1 +ATOM 9459 C CB . ILE E 1 249 ? 50.678 -34.490 89.465 1.00 161.07 ? 249 ILE E CB 1 +ATOM 9460 C CG1 . ILE E 1 249 ? 49.545 -35.340 90.060 1.00 152.55 ? 249 ILE E CG1 1 +ATOM 9461 C CG2 . ILE E 1 249 ? 50.475 -34.350 87.964 1.00 194.10 ? 249 ILE E CG2 1 +ATOM 9462 C CD1 . ILE E 1 249 ? 48.239 -34.593 90.254 1.00 143.63 ? 249 ILE E CD1 1 +ATOM 9463 N N . LEU E 1 250 ? 53.463 -33.170 89.605 1.00 141.85 ? 250 LEU E N 1 +ATOM 9464 C CA . LEU E 1 250 ? 54.481 -32.289 89.020 1.00 137.49 ? 250 LEU E CA 1 +ATOM 9465 C C . LEU E 1 250 ? 55.866 -32.929 88.977 1.00 141.53 ? 250 LEU E C 1 +ATOM 9466 O O . LEU E 1 250 ? 56.603 -32.743 88.009 1.00 133.19 ? 250 LEU E O 1 +ATOM 9467 C CB . LEU E 1 250 ? 54.549 -30.965 89.784 1.00 133.32 ? 250 LEU E CB 1 +ATOM 9468 C CG . LEU E 1 250 ? 53.460 -29.945 89.430 1.00 135.89 ? 250 LEU E CG 1 +ATOM 9469 C CD1 . LEU E 1 250 ? 53.410 -28.792 90.424 1.00 129.44 ? 250 LEU E CD1 1 +ATOM 9470 C CD2 . LEU E 1 250 ? 53.682 -29.417 88.025 1.00 139.40 ? 250 LEU E CD2 1 +ATOM 9471 N N . VAL E 1 251 ? 56.207 -33.684 90.021 1.00 153.89 ? 251 VAL E N 1 +ATOM 9472 C CA . VAL E 1 251 ? 57.498 -34.379 90.067 1.00 156.98 ? 251 VAL E CA 1 +ATOM 9473 C C . VAL E 1 251 ? 57.500 -35.629 89.187 1.00 164.64 ? 251 VAL E C 1 +ATOM 9474 O O . VAL E 1 251 ? 58.555 -36.068 88.723 1.00 183.53 ? 251 VAL E O 1 +ATOM 9475 C CB . VAL E 1 251 ? 57.916 -34.763 91.505 1.00 136.81 ? 251 VAL E CB 1 +ATOM 9476 C CG1 . VAL E 1 251 ? 57.916 -33.531 92.401 1.00 138.47 ? 251 VAL E CG1 1 +ATOM 9477 C CG2 . VAL E 1 251 ? 57.023 -35.864 92.067 1.00 127.23 ? 251 VAL E CG2 1 +ATOM 9478 N N . LYS E 1 252 ? 56.320 -36.197 88.960 1.00 148.06 ? 252 LYS E N 1 +ATOM 9479 C CA . LYS E 1 252 ? 56.182 -37.331 88.055 1.00 141.13 ? 252 LYS E CA 1 +ATOM 9480 C C . LYS E 1 252 ? 56.496 -36.909 86.606 1.00 153.87 ? 252 LYS E C 1 +ATOM 9481 O O . LYS E 1 252 ? 57.268 -37.570 85.897 1.00 119.88 ? 252 LYS E O 1 +ATOM 9482 C CB . LYS E 1 252 ? 54.768 -37.901 88.183 1.00 123.01 ? 252 LYS E CB 1 +ATOM 9483 C CG . LYS E 1 252 ? 54.463 -39.080 87.279 1.00 122.71 ? 252 LYS E CG 1 +ATOM 9484 C CD . LYS E 1 252 ? 53.026 -39.531 87.486 1.00 129.65 ? 252 LYS E CD 1 +ATOM 9485 C CE . LYS E 1 252 ? 52.307 -39.735 86.160 1.00 165.44 ? 252 LYS E CE 1 +ATOM 9486 N NZ . LYS E 1 252 ? 50.834 -39.917 86.321 1.00 152.27 ? 252 LYS E NZ 1 +ATOM 9487 N N . TYR E 1 253 ? 55.929 -35.778 86.186 1.00 170.78 ? 253 TYR E N 1 +ATOM 9488 C CA . TYR E 1 253 ? 56.135 -35.265 84.825 1.00 160.07 ? 253 TYR E CA 1 +ATOM 9489 C C . TYR E 1 253 ? 57.497 -34.610 84.681 1.00 152.61 ? 253 TYR E C 1 +ATOM 9490 O O . TYR E 1 253 ? 58.106 -34.641 83.603 1.00 129.06 ? 253 TYR E O 1 +ATOM 9491 C CB . TYR E 1 253 ? 55.016 -34.290 84.430 1.00 157.91 ? 253 TYR E CB 1 +ATOM 9492 C CG . TYR E 1 253 ? 53.702 -35.023 84.189 1.00 186.54 ? 253 TYR E CG 1 +ATOM 9493 C CD1 . TYR E 1 253 ? 53.425 -35.615 82.954 1.00 182.13 ? 253 TYR E CD1 1 +ATOM 9494 C CD2 . TYR E 1 253 ? 52.779 -35.203 85.219 1.00 184.04 ? 253 TYR E CD2 1 +ATOM 9495 C CE1 . TYR E 1 253 ? 52.252 -36.317 82.747 1.00 148.00 ? 253 TYR E CE1 1 +ATOM 9496 C CE2 . TYR E 1 253 ? 51.592 -35.898 85.010 1.00 133.50 ? 253 TYR E CE2 1 +ATOM 9497 C CZ . TYR E 1 253 ? 51.334 -36.442 83.773 1.00 124.20 ? 253 TYR E CZ 1 +ATOM 9498 O OH . TYR E 1 253 ? 50.173 -37.124 83.548 1.00 95.29 ? 253 TYR E OH 1 +ATOM 9499 N N . ARG E 1 254 ? 57.968 -34.011 85.771 1.00 154.64 ? 254 ARG E N 1 +ATOM 9500 C CA . ARG E 1 254 ? 59.342 -33.523 85.843 1.00 152.36 ? 254 ARG E CA 1 +ATOM 9501 C C . ARG E 1 254 ? 60.315 -34.680 85.601 1.00 133.52 ? 254 ARG E C 1 +ATOM 9502 O O . ARG E 1 254 ? 61.329 -34.511 84.910 1.00 125.21 ? 254 ARG E O 1 +ATOM 9503 C CB . ARG E 1 254 ? 59.621 -32.886 87.214 1.00 170.84 ? 254 ARG E CB 1 +ATOM 9504 C CG . ARG E 1 254 ? 61.001 -32.256 87.320 1.00 175.25 ? 254 ARG E CG 1 +ATOM 9505 C CD . ARG E 1 254 ? 61.119 -31.290 88.487 1.00 178.47 ? 254 ARG E CD 1 +ATOM 9506 N NE . ARG E 1 254 ? 60.275 -30.101 88.356 1.00 164.87 ? 254 ARG E NE 1 +ATOM 9507 C CZ . ARG E 1 254 ? 59.173 -29.857 89.063 1.00 163.16 ? 254 ARG E CZ 1 +ATOM 9508 N NH1 . ARG E 1 254 ? 58.727 -30.738 89.955 1.00 170.16 ? 254 ARG E NH1 1 +ATOM 9509 N NH2 . ARG E 1 254 ? 58.505 -28.725 88.874 1.00 160.98 ? 254 ARG E NH2 1 +ATOM 9510 N N . HIS E 1 255 ? 59.992 -35.847 86.166 1.00 131.36 ? 255 HIS E N 1 +ATOM 9511 C CA . HIS E 1 255 ? 60.824 -37.045 86.030 1.00 149.32 ? 255 HIS E CA 1 +ATOM 9512 C C . HIS E 1 255 ? 60.816 -37.617 84.616 1.00 150.28 ? 255 HIS E C 1 +ATOM 9513 O O . HIS E 1 255 ? 61.839 -38.116 84.139 1.00 177.09 ? 255 HIS E O 1 +ATOM 9514 C CB . HIS E 1 255 ? 60.391 -38.130 87.023 1.00 156.41 ? 255 HIS E CB 1 +ATOM 9515 C CG . HIS E 1 255 ? 61.326 -38.306 88.176 1.00 171.07 ? 255 HIS E CG 1 +ATOM 9516 N ND1 . HIS E 1 255 ? 61.390 -37.414 89.225 1.00 161.86 ? 255 HIS E ND1 1 +ATOM 9517 C CD2 . HIS E 1 255 ? 62.238 -39.271 88.444 1.00 179.65 ? 255 HIS E CD2 1 +ATOM 9518 C CE1 . HIS E 1 255 ? 62.310 -37.817 90.084 1.00 184.67 ? 255 HIS E CE1 1 +ATOM 9519 N NE2 . HIS E 1 255 ? 62.839 -38.941 89.634 1.00 187.57 ? 255 HIS E NE2 1 +ATOM 9520 N N . MET E 1 256 ? 59.687 -37.516 83.926 1.00 143.54 ? 256 MET E N 1 +ATOM 9521 C CA . MET E 1 256 ? 59.623 -38.000 82.546 1.00 143.43 ? 256 MET E CA 1 +ATOM 9522 C C . MET E 1 256 ? 60.504 -37.159 81.591 1.00 166.38 ? 256 MET E C 1 +ATOM 9523 O O . MET E 1 256 ? 60.939 -37.661 80.545 1.00 140.55 ? 256 MET E O 1 +ATOM 9524 C CB . MET E 1 256 ? 58.168 -38.056 82.069 1.00 153.13 ? 256 MET E CB 1 +ATOM 9525 C CG . MET E 1 256 ? 57.246 -38.835 83.004 1.00 155.80 ? 256 MET E CG 1 +ATOM 9526 S SD . MET E 1 256 ? 55.684 -39.385 82.283 1.00 169.07 ? 256 MET E SD 1 +ATOM 9527 C CE . MET E 1 256 ? 56.292 -40.642 81.146 1.00 146.30 ? 256 MET E CE 1 +ATOM 9528 N N . SER E 1 257 ? 60.775 -35.901 81.969 1.00 172.08 ? 257 SER E N 1 +ATOM 9529 C CA . SER E 1 257 ? 61.688 -35.017 81.228 1.00 140.14 ? 257 SER E CA 1 +ATOM 9530 C C . SER E 1 257 ? 63.140 -35.378 81.502 1.00 113.46 ? 257 SER E C 1 +ATOM 9531 O O . SER E 1 257 ? 63.707 -36.222 80.798 1.00 142.40 ? 257 SER E O 1 +ATOM 9532 C CB . SER E 1 257 ? 61.457 -33.553 81.610 1.00 121.90 ? 257 SER E CB 1 +ATOM 9533 O OG . SER E 1 257 ? 60.068 -33.270 81.700 1.00 97.17 ? 257 SER E OG 1 +ATOM 9534 N N . LEU F 1 2 ? 28.960 -55.358 80.031 1.00 144.49 ? 2 LEU F N 1 +ATOM 9535 C CA . LEU F 1 2 ? 29.905 -54.413 79.288 1.00 138.92 ? 2 LEU F CA 1 +ATOM 9536 C C . LEU F 1 2 ? 29.819 -54.169 77.758 1.00 139.36 ? 2 LEU F C 1 +ATOM 9537 O O . LEU F 1 2 ? 30.268 -54.994 76.953 1.00 105.87 ? 2 LEU F O 1 +ATOM 9538 C CB . LEU F 1 2 ? 31.350 -54.790 79.579 1.00 134.07 ? 2 LEU F CB 1 +ATOM 9539 C CG . LEU F 1 2 ? 31.893 -54.710 81.016 1.00 125.33 ? 2 LEU F CG 1 +ATOM 9540 C CD1 . LEU F 1 2 ? 33.358 -55.134 81.015 1.00 119.08 ? 2 LEU F CD1 1 +ATOM 9541 C CD2 . LEU F 1 2 ? 31.731 -53.339 81.676 1.00 109.96 ? 2 LEU F CD2 1 +ATOM 9542 N N . THR F 1 3 ? 29.356 -52.966 77.398 1.00 152.83 ? 3 THR F N 1 +ATOM 9543 C CA . THR F 1 3 ? 29.167 -52.507 76.006 1.00 166.11 ? 3 THR F CA 1 +ATOM 9544 C C . THR F 1 3 ? 29.315 -50.966 75.874 1.00 174.06 ? 3 THR F C 1 +ATOM 9545 O O . THR F 1 3 ? 29.166 -50.381 74.780 1.00 118.81 ? 3 THR F O 1 +ATOM 9546 C CB . THR F 1 3 ? 27.763 -52.885 75.501 1.00 165.74 ? 3 THR F CB 1 +ATOM 9547 O OG1 . THR F 1 3 ? 26.769 -52.127 76.220 1.00 165.31 ? 3 THR F OG1 1 +ATOM 9548 C CG2 . THR F 1 3 ? 27.529 -54.391 75.658 1.00 154.81 ? 3 THR F CG2 1 +ATOM 9549 N N . ALA F 1 4 ? 29.551 -50.302 76.999 1.00 174.02 ? 4 ALA F N 1 +ATOM 9550 C CA . ALA F 1 4 ? 30.147 -48.971 76.985 1.00 143.29 ? 4 ALA F CA 1 +ATOM 9551 C C . ALA F 1 4 ? 31.641 -49.126 76.624 1.00 133.90 ? 4 ALA F C 1 +ATOM 9552 O O . ALA F 1 4 ? 32.104 -50.223 76.310 1.00 100.74 ? 4 ALA F O 1 +ATOM 9553 C CB . ALA F 1 4 ? 29.950 -48.287 78.337 1.00 129.02 ? 4 ALA F CB 1 +ATOM 9554 N N . PRO F 1 5 ? 32.409 -48.030 76.622 1.00 141.79 ? 5 PRO F N 1 +ATOM 9555 C CA . PRO F 1 5 ? 33.686 -48.260 75.962 1.00 131.07 ? 5 PRO F CA 1 +ATOM 9556 C C . PRO F 1 5 ? 34.702 -48.998 76.839 1.00 109.65 ? 5 PRO F C 1 +ATOM 9557 O O . PRO F 1 5 ? 34.513 -49.118 78.047 1.00 121.20 ? 5 PRO F O 1 +ATOM 9558 C CB . PRO F 1 5 ? 34.148 -46.834 75.625 1.00 150.98 ? 5 PRO F CB 1 +ATOM 9559 C CG . PRO F 1 5 ? 33.503 -45.944 76.656 1.00 138.45 ? 5 PRO F CG 1 +ATOM 9560 C CD . PRO F 1 5 ? 32.322 -46.682 77.229 1.00 141.89 ? 5 PRO F CD 1 +ATOM 9561 N N . PRO F 1 6 ? 35.810 -49.432 76.246 1.00 96.43 ? 6 PRO F N 1 +ATOM 9562 C CA . PRO F 1 6 ? 36.998 -49.825 77.021 1.00 105.52 ? 6 PRO F CA 1 +ATOM 9563 C C . PRO F 1 6 ? 37.827 -48.654 77.528 1.00 96.19 ? 6 PRO F C 1 +ATOM 9564 O O . PRO F 1 6 ? 37.865 -47.605 76.898 1.00 72.09 ? 6 PRO F O 1 +ATOM 9565 C CB . PRO F 1 6 ? 37.809 -50.674 76.038 1.00 112.95 ? 6 PRO F CB 1 +ATOM 9566 C CG . PRO F 1 6 ? 37.293 -50.335 74.682 1.00 106.73 ? 6 PRO F CG 1 +ATOM 9567 C CD . PRO F 1 6 ? 35.953 -49.673 74.806 1.00 93.16 ? 6 PRO F CD 1 +ATOM 9568 N N . LYS F 1 7 ? 38.551 -48.852 78.624 1.00 123.65 ? 7 LYS F N 1 +ATOM 9569 C CA . LYS F 1 7 ? 39.385 -47.779 79.162 1.00 160.02 ? 7 LYS F CA 1 +ATOM 9570 C C . LYS F 1 7 ? 40.843 -47.879 78.709 1.00 151.65 ? 7 LYS F C 1 +ATOM 9571 O O . LYS F 1 7 ? 41.295 -48.923 78.195 1.00 100.80 ? 7 LYS F O 1 +ATOM 9572 C CB . LYS F 1 7 ? 39.307 -47.724 80.693 1.00 182.88 ? 7 LYS F CB 1 +ATOM 9573 C CG . LYS F 1 7 ? 37.959 -47.302 81.240 1.00 192.26 ? 7 LYS F CG 1 +ATOM 9574 C CD . LYS F 1 7 ? 37.144 -48.468 81.792 1.00 184.89 ? 7 LYS F CD 1 +ATOM 9575 C CE . LYS F 1 7 ? 35.960 -47.962 82.597 1.00 178.02 ? 7 LYS F CE 1 +ATOM 9576 N NZ . LYS F 1 7 ? 34.815 -48.913 82.565 1.00 163.55 ? 7 LYS F NZ 1 +ATOM 9577 N N . GLU F 1 8 ? 41.583 -46.786 78.916 1.00 179.10 ? 8 GLU F N 1 +ATOM 9578 C CA . GLU F 1 8 ? 42.898 -46.612 78.259 1.00 212.17 ? 8 GLU F CA 1 +ATOM 9579 C C . GLU F 1 8 ? 44.009 -47.531 78.760 1.00 174.04 ? 8 GLU F C 1 +ATOM 9580 O O . GLU F 1 8 ? 44.320 -47.583 79.936 1.00 129.00 ? 8 GLU F O 1 +ATOM 9581 C CB . GLU F 1 8 ? 43.359 -45.158 78.086 1.00 240.80 ? 8 GLU F CB 1 +ATOM 9582 C CG . GLU F 1 8 ? 42.569 -44.074 78.739 1.00 242.71 ? 8 GLU F CG 1 +ATOM 9583 C CD . GLU F 1 8 ? 42.990 -42.675 78.264 1.00 188.64 ? 8 GLU F CD 1 +ATOM 9584 O OE1 . GLU F 1 8 ? 44.186 -42.323 78.381 1.00 164.20 ? 8 GLU F OE1 1 +ATOM 9585 O OE2 . GLU F 1 8 ? 42.125 -41.894 77.826 1.00 104.26 ? 8 GLU F OE2 1 +ATOM 9586 N N . ALA F 1 9 ? 44.535 -48.329 77.839 1.00 155.22 ? 9 ALA F N 1 +ATOM 9587 C CA . ALA F 1 9 ? 45.661 -49.228 78.101 1.00 134.62 ? 9 ALA F CA 1 +ATOM 9588 C C . ALA F 1 9 ? 46.991 -48.612 77.644 1.00 144.08 ? 9 ALA F C 1 +ATOM 9589 O O . ALA F 1 9 ? 47.140 -48.333 76.461 1.00 200.30 ? 9 ALA F O 1 +ATOM 9590 C CB . ALA F 1 9 ? 45.421 -50.528 77.360 1.00 128.04 ? 9 ALA F CB 1 +ATOM 9591 N N . ALA F 1 10 ? 47.942 -48.440 78.572 1.00 124.46 ? 10 ALA F N 1 +ATOM 9592 C CA . ALA F 1 10 ? 49.229 -47.764 78.329 1.00 117.31 ? 10 ALA F CA 1 +ATOM 9593 C C . ALA F 1 10 ? 49.142 -46.238 78.427 1.00 132.06 ? 10 ALA F C 1 +ATOM 9594 O O . ALA F 1 10 ? 48.062 -45.652 78.271 1.00 125.13 ? 10 ALA F O 1 +ATOM 9595 C CB . ALA F 1 10 ? 49.846 -48.198 77.006 1.00 86.11 ? 10 ALA F CB 1 +ATOM 9596 N N . ARG F 1 11 ? 50.292 -45.605 78.692 1.00 151.61 ? 11 ARG F N 1 +ATOM 9597 C CA . ARG F 1 11 ? 50.347 -44.190 79.077 1.00 158.33 ? 11 ARG F CA 1 +ATOM 9598 C C . ARG F 1 11 ? 50.915 -43.297 77.971 1.00 151.56 ? 11 ARG F C 1 +ATOM 9599 O O . ARG F 1 11 ? 51.758 -43.724 77.179 1.00 164.99 ? 11 ARG F O 1 +ATOM 9600 C CB . ARG F 1 11 ? 51.227 -44.016 80.325 1.00 179.31 ? 11 ARG F CB 1 +ATOM 9601 C CG . ARG F 1 11 ? 52.713 -44.252 80.098 1.00 185.60 ? 11 ARG F CG 1 +ATOM 9602 C CD . ARG F 1 11 ? 53.398 -44.705 81.380 1.00 181.79 ? 11 ARG F CD 1 +ATOM 9603 N NE . ARG F 1 11 ? 53.863 -46.069 81.256 1.00 191.65 ? 11 ARG F NE 1 +ATOM 9604 C CZ . ARG F 1 11 ? 53.104 -47.171 81.197 1.00 190.88 ? 11 ARG F CZ 1 +ATOM 9605 N NH1 . ARG F 1 11 ? 51.771 -47.143 81.276 1.00 196.30 ? 11 ARG F NH1 1 +ATOM 9606 N NH2 . ARG F 1 11 ? 53.708 -48.348 81.069 1.00 194.80 ? 11 ARG F NH2 1 +ATOM 9607 N N . PRO F 1 12 ? 50.497 -42.026 77.943 1.00 138.95 ? 12 PRO F N 1 +ATOM 9608 C CA . PRO F 1 12 ? 51.212 -41.088 77.096 1.00 144.35 ? 12 PRO F CA 1 +ATOM 9609 C C . PRO F 1 12 ? 52.610 -40.851 77.643 1.00 125.13 ? 12 PRO F C 1 +ATOM 9610 O O . PRO F 1 12 ? 52.771 -40.364 78.768 1.00 167.90 ? 12 PRO F O 1 +ATOM 9611 C CB . PRO F 1 12 ? 50.377 -39.800 77.186 1.00 172.69 ? 12 PRO F CB 1 +ATOM 9612 C CG . PRO F 1 12 ? 49.077 -40.193 77.800 1.00 171.18 ? 12 PRO F CG 1 +ATOM 9613 C CD . PRO F 1 12 ? 49.391 -41.381 78.662 1.00 151.31 ? 12 PRO F CD 1 +ATOM 9614 N N . THR F 1 13 ? 53.610 -41.256 76.876 1.00 102.27 ? 13 THR F N 1 +ATOM 9615 C CA . THR F 1 13 ? 54.983 -40.867 77.144 1.00 103.75 ? 13 THR F CA 1 +ATOM 9616 C C . THR F 1 13 ? 55.331 -39.613 76.338 1.00 112.47 ? 13 THR F C 1 +ATOM 9617 O O . THR F 1 13 ? 54.682 -39.354 75.335 1.00 154.46 ? 13 THR F O 1 +ATOM 9618 C CB . THR F 1 13 ? 55.942 -42.020 76.776 1.00 87.88 ? 13 THR F CB 1 +ATOM 9619 O OG1 . THR F 1 13 ? 57.260 -41.693 77.262 1.00 161.19 ? 13 THR F OG1 1 +ATOM 9620 C CG2 . THR F 1 13 ? 55.967 -42.293 75.249 1.00 54.96 ? 13 THR F CG2 1 +ATOM 9621 N N . LEU F 1 14 ? 56.366 -38.866 76.726 1.00 106.98 ? 14 LEU F N 1 +ATOM 9622 C CA . LEU F 1 14 ? 56.890 -37.877 75.789 1.00 102.74 ? 14 LEU F CA 1 +ATOM 9623 C C . LEU F 1 14 ? 57.678 -38.583 74.654 1.00 114.31 ? 14 LEU F C 1 +ATOM 9624 O O . LEU F 1 14 ? 57.993 -39.752 74.778 1.00 126.78 ? 14 LEU F O 1 +ATOM 9625 C CB . LEU F 1 14 ? 57.693 -36.780 76.460 1.00 83.69 ? 14 LEU F CB 1 +ATOM 9626 C CG . LEU F 1 14 ? 58.878 -37.181 77.298 1.00 98.97 ? 14 LEU F CG 1 +ATOM 9627 C CD1 . LEU F 1 14 ? 59.976 -36.135 77.203 1.00 102.30 ? 14 LEU F CD1 1 +ATOM 9628 C CD2 . LEU F 1 14 ? 58.405 -37.314 78.721 1.00 134.38 ? 14 LEU F CD2 1 +ATOM 9629 N N . MET F 1 15 ? 57.796 -37.946 73.488 1.00 120.93 ? 15 MET F N 1 +ATOM 9630 C CA . MET F 1 15 ? 57.949 -38.688 72.221 1.00 119.78 ? 15 MET F CA 1 +ATOM 9631 C C . MET F 1 15 ? 59.328 -39.324 72.181 1.00 95.51 ? 15 MET F C 1 +ATOM 9632 O O . MET F 1 15 ? 60.330 -38.628 72.301 1.00 76.62 ? 15 MET F O 1 +ATOM 9633 C CB . MET F 1 15 ? 57.699 -37.805 70.980 1.00 125.29 ? 15 MET F CB 1 +ATOM 9634 C CG . MET F 1 15 ? 57.196 -38.602 69.783 1.00 110.05 ? 15 MET F CG 1 +ATOM 9635 S SD . MET F 1 15 ? 57.797 -38.259 68.128 1.00 117.40 ? 15 MET F SD 1 +ATOM 9636 C CE . MET F 1 15 ? 59.200 -37.166 68.267 1.00 84.01 ? 15 MET F CE 1 +ATOM 9637 N N . PRO F 1 16 ? 59.370 -40.652 72.009 1.00 93.29 ? 16 PRO F N 1 +ATOM 9638 C CA . PRO F 1 16 ? 60.585 -41.449 72.091 1.00 105.30 ? 16 PRO F CA 1 +ATOM 9639 C C . PRO F 1 16 ? 61.636 -41.113 71.017 1.00 103.60 ? 16 PRO F C 1 +ATOM 9640 O O . PRO F 1 16 ? 61.809 -41.844 70.047 1.00 92.06 ? 16 PRO F O 1 +ATOM 9641 C CB . PRO F 1 16 ? 60.069 -42.893 71.945 1.00 106.70 ? 16 PRO F CB 1 +ATOM 9642 C CG . PRO F 1 16 ? 58.804 -42.759 71.200 1.00 105.97 ? 16 PRO F CG 1 +ATOM 9643 C CD . PRO F 1 16 ? 58.198 -41.487 71.700 1.00 100.51 ? 16 PRO F CD 1 +ATOM 9644 N N . ARG F 1 17 ? 62.415 -40.067 71.273 1.00 113.34 ? 17 ARG F N 1 +ATOM 9645 C CA . ARG F 1 17 ? 63.584 -39.742 70.459 1.00 97.66 ? 17 ARG F CA 1 +ATOM 9646 C C . ARG F 1 17 ? 64.803 -40.504 70.980 1.00 103.37 ? 17 ARG F C 1 +ATOM 9647 O O . ARG F 1 17 ? 64.936 -40.688 72.188 1.00 99.97 ? 17 ARG F O 1 +ATOM 9648 C CB . ARG F 1 17 ? 63.828 -38.221 70.499 1.00 70.22 ? 17 ARG F CB 1 +ATOM 9649 C CG . ARG F 1 17 ? 63.034 -37.460 69.453 1.00 66.56 ? 17 ARG F CG 1 +ATOM 9650 C CD . ARG F 1 17 ? 62.933 -35.966 69.716 1.00 62.11 ? 17 ARG F CD 1 +ATOM 9651 N NE . ARG F 1 17 ? 61.945 -35.679 70.741 1.00 84.24 ? 17 ARG F NE 1 +ATOM 9652 C CZ . ARG F 1 17 ? 61.736 -34.476 71.255 1.00 117.49 ? 17 ARG F CZ 1 +ATOM 9653 N NH1 . ARG F 1 17 ? 62.430 -33.441 70.800 1.00 126.47 ? 17 ARG F NH1 1 +ATOM 9654 N NH2 . ARG F 1 17 ? 60.805 -34.304 72.204 1.00 143.85 ? 17 ARG F NH2 1 +ATOM 9655 N N . ALA F 1 18 ? 65.708 -40.907 70.091 1.00 102.17 ? 18 ALA F N 1 +ATOM 9656 C CA . ALA F 1 18 ? 66.897 -41.654 70.517 1.00 121.21 ? 18 ALA F CA 1 +ATOM 9657 C C . ALA F 1 18 ? 68.246 -40.899 70.385 1.00 112.10 ? 18 ALA F C 1 +ATOM 9658 O O . ALA F 1 18 ? 68.456 -39.863 71.018 1.00 74.16 ? 18 ALA F O 1 +ATOM 9659 C CB . ALA F 1 18 ? 66.947 -42.987 69.791 1.00 155.92 ? 18 ALA F CB 1 +ATOM 9660 N N . GLN F 1 19 ? 69.150 -41.420 69.560 1.00 125.99 ? 19 GLN F N 1 +ATOM 9661 C CA . GLN F 1 19 ? 70.554 -41.035 69.633 1.00 129.22 ? 19 GLN F CA 1 +ATOM 9662 C C . GLN F 1 19 ? 70.788 -39.610 69.131 1.00 120.53 ? 19 GLN F C 1 +ATOM 9663 O O . GLN F 1 19 ? 71.466 -38.801 69.781 1.00 106.49 ? 19 GLN F O 1 +ATOM 9664 C CB . GLN F 1 19 ? 71.400 -42.012 68.808 1.00 168.51 ? 19 GLN F CB 1 +ATOM 9665 C CG . GLN F 1 19 ? 72.902 -41.793 68.932 1.00 211.87 ? 19 GLN F CG 1 +ATOM 9666 C CD . GLN F 1 19 ? 73.381 -41.799 70.374 1.00 209.87 ? 19 GLN F CD 1 +ATOM 9667 O OE1 . GLN F 1 19 ? 73.335 -42.835 71.045 1.00 244.58 ? 19 GLN F OE1 1 +ATOM 9668 N NE2 . GLN F 1 19 ? 73.842 -40.646 70.857 1.00 162.09 ? 19 GLN F NE2 1 +ATOM 9669 N N . SER F 1 20 ? 70.248 -39.335 67.942 1.00 124.84 ? 20 SER F N 1 +ATOM 9670 C CA . SER F 1 20 ? 70.251 -37.999 67.347 1.00 108.74 ? 20 SER F CA 1 +ATOM 9671 C C . SER F 1 20 ? 69.900 -36.926 68.398 1.00 101.84 ? 20 SER F C 1 +ATOM 9672 O O . SER F 1 20 ? 70.626 -35.954 68.561 1.00 131.45 ? 20 SER F O 1 +ATOM 9673 C CB . SER F 1 20 ? 69.250 -37.957 66.181 1.00 94.00 ? 20 SER F CB 1 +ATOM 9674 O OG . SER F 1 20 ? 69.461 -39.027 65.287 1.00 71.84 ? 20 SER F OG 1 +ATOM 9675 N N . TYR F 1 21 ? 68.819 -37.157 69.140 1.00 77.44 ? 21 TYR F N 1 +ATOM 9676 C CA . TYR F 1 21 ? 68.394 -36.281 70.228 1.00 74.39 ? 21 TYR F CA 1 +ATOM 9677 C C . TYR F 1 21 ? 69.458 -36.077 71.307 1.00 91.96 ? 21 TYR F C 1 +ATOM 9678 O O . TYR F 1 21 ? 69.763 -34.949 71.682 1.00 92.81 ? 21 TYR F O 1 +ATOM 9679 C CB . TYR F 1 21 ? 67.138 -36.862 70.897 1.00 83.18 ? 21 TYR F CB 1 +ATOM 9680 C CG . TYR F 1 21 ? 66.587 -36.002 71.998 1.00 111.71 ? 21 TYR F CG 1 +ATOM 9681 C CD1 . TYR F 1 21 ? 65.902 -34.805 71.683 1.00 188.56 ? 21 TYR F CD1 1 +ATOM 9682 C CD2 . TYR F 1 21 ? 66.771 -36.321 73.328 1.00 74.61 ? 21 TYR F CD2 1 +ATOM 9683 C CE1 . TYR F 1 21 ? 65.403 -33.972 72.665 1.00 163.07 ? 21 TYR F CE1 1 +ATOM 9684 C CE2 . TYR F 1 21 ? 66.273 -35.488 74.313 1.00 109.29 ? 21 TYR F CE2 1 +ATOM 9685 C CZ . TYR F 1 21 ? 65.574 -34.321 73.970 1.00 141.44 ? 21 TYR F CZ 1 +ATOM 9686 O OH . TYR F 1 21 ? 65.071 -33.460 74.919 1.00 138.92 ? 21 TYR F OH 1 +ATOM 9687 N N . LYS F 1 22 ? 70.017 -37.178 71.797 1.00 135.10 ? 22 LYS F N 1 +ATOM 9688 C CA . LYS F 1 22 ? 71.041 -37.131 72.841 1.00 126.67 ? 22 LYS F CA 1 +ATOM 9689 C C . LYS F 1 22 ? 72.284 -36.347 72.427 1.00 108.14 ? 22 LYS F C 1 +ATOM 9690 O O . LYS F 1 22 ? 72.821 -35.572 73.219 1.00 116.37 ? 22 LYS F O 1 +ATOM 9691 C CB . LYS F 1 22 ? 71.465 -38.547 73.222 1.00 148.56 ? 22 LYS F CB 1 +ATOM 9692 C CG . LYS F 1 22 ? 70.609 -39.157 74.309 1.00 149.61 ? 22 LYS F CG 1 +ATOM 9693 C CD . LYS F 1 22 ? 71.071 -38.669 75.690 1.00 121.78 ? 22 LYS F CD 1 +ATOM 9694 C CE . LYS F 1 22 ? 71.904 -39.754 76.377 1.00 131.04 ? 22 LYS F CE 1 +ATOM 9695 N NZ . LYS F 1 22 ? 71.087 -40.965 76.681 1.00 160.27 ? 22 LYS F NZ 1 +ATOM 9696 N N . ASP F 1 23 ? 72.718 -36.541 71.182 1.00 106.65 ? 23 ASP F N 1 +ATOM 9697 C CA . ASP F 1 23 ? 73.781 -35.724 70.591 1.00 114.87 ? 23 ASP F CA 1 +ATOM 9698 C C . ASP F 1 23 ? 73.395 -34.243 70.486 1.00 139.47 ? 23 ASP F C 1 +ATOM 9699 O O . ASP F 1 23 ? 74.157 -33.350 70.873 1.00 141.02 ? 23 ASP F O 1 +ATOM 9700 C CB . ASP F 1 23 ? 74.127 -36.232 69.191 1.00 96.31 ? 23 ASP F CB 1 +ATOM 9701 C CG . ASP F 1 23 ? 74.727 -37.586 69.223 1.00 106.32 ? 23 ASP F CG 1 +ATOM 9702 O OD1 . ASP F 1 23 ? 75.575 -37.818 70.118 1.00 144.14 ? 23 ASP F OD1 1 +ATOM 9703 O OD2 . ASP F 1 23 ? 74.403 -38.404 68.344 1.00 94.74 ? 23 ASP F OD2 1 +ATOM 9704 N N . LEU F 1 24 ? 72.180 -33.997 70.004 1.00 160.76 ? 24 LEU F N 1 +ATOM 9705 C CA . LEU F 1 24 ? 71.683 -32.642 69.754 1.00 150.18 ? 24 LEU F CA 1 +ATOM 9706 C C . LEU F 1 24 ? 71.575 -31.802 71.041 1.00 139.90 ? 24 LEU F C 1 +ATOM 9707 O O . LEU F 1 24 ? 71.800 -30.589 71.028 1.00 136.45 ? 24 LEU F O 1 +ATOM 9708 C CB . LEU F 1 24 ? 70.308 -32.724 69.060 1.00 152.74 ? 24 LEU F CB 1 +ATOM 9709 C CG . LEU F 1 24 ? 69.605 -31.416 68.685 1.00 132.81 ? 24 LEU F CG 1 +ATOM 9710 C CD1 . LEU F 1 24 ? 70.095 -30.916 67.326 1.00 150.02 ? 24 LEU F CD1 1 +ATOM 9711 C CD2 . LEU F 1 24 ? 68.096 -31.604 68.681 1.00 97.00 ? 24 LEU F CD2 1 +ATOM 9712 N N . THR F 1 25 ? 71.185 -32.450 72.136 1.00 137.95 ? 25 THR F N 1 +ATOM 9713 C CA . THR F 1 25 ? 70.971 -31.761 73.412 1.00 137.76 ? 25 THR F CA 1 +ATOM 9714 C C . THR F 1 25 ? 72.287 -31.401 74.080 1.00 112.20 ? 25 THR F C 1 +ATOM 9715 O O . THR F 1 25 ? 72.465 -30.279 74.545 1.00 72.51 ? 25 THR F O 1 +ATOM 9716 C CB . THR F 1 25 ? 70.115 -32.620 74.376 1.00 194.63 ? 25 THR F CB 1 +ATOM 9717 O OG1 . THR F 1 25 ? 70.584 -33.978 74.380 1.00 260.10 ? 25 THR F OG1 1 +ATOM 9718 C CG2 . THR F 1 25 ? 68.656 -32.607 73.939 1.00 218.62 ? 25 THR F CG2 1 +ATOM 9719 N N . HIS F 1 26 ? 73.204 -32.374 74.131 1.00 146.62 ? 26 HIS F N 1 +ATOM 9720 C CA . HIS F 1 26 ? 74.500 -32.223 74.822 1.00 127.45 ? 26 HIS F CA 1 +ATOM 9721 C C . HIS F 1 26 ? 75.544 -31.519 73.941 1.00 89.33 ? 26 HIS F C 1 +ATOM 9722 O O . HIS F 1 26 ? 76.701 -31.893 73.917 1.00 76.08 ? 26 HIS F O 1 +ATOM 9723 C CB . HIS F 1 26 ? 74.999 -33.607 75.316 1.00 128.73 ? 26 HIS F CB 1 +ATOM 9724 C CG . HIS F 1 26 ? 74.120 -34.240 76.366 1.00 145.17 ? 26 HIS F CG 1 +ATOM 9725 N ND1 . HIS F 1 26 ? 72.859 -34.730 76.093 1.00 168.41 ? 26 HIS F ND1 1 +ATOM 9726 C CD2 . HIS F 1 26 ? 74.321 -34.457 77.690 1.00 158.21 ? 26 HIS F CD2 1 +ATOM 9727 C CE1 . HIS F 1 26 ? 72.317 -35.204 77.203 1.00 144.79 ? 26 HIS F CE1 1 +ATOM 9728 N NE2 . HIS F 1 26 ? 73.186 -35.060 78.184 1.00 141.64 ? 26 HIS F NE2 1 +ATOM 9729 N N . LEU F 1 27 ? 75.090 -30.596 73.108 1.00 89.34 ? 27 LEU F N 1 +ATOM 9730 C CA . LEU F 1 27 ? 75.995 -29.850 72.251 1.00 103.82 ? 27 LEU F CA 1 +ATOM 9731 C C . LEU F 1 27 ? 76.479 -28.624 73.018 1.00 108.93 ? 27 LEU F C 1 +ATOM 9732 O O . LEU F 1 27 ? 75.680 -27.939 73.648 1.00 81.14 ? 27 LEU F O 1 +ATOM 9733 C CB . LEU F 1 27 ? 75.304 -29.415 70.947 1.00 122.45 ? 27 LEU F CB 1 +ATOM 9734 C CG . LEU F 1 27 ? 75.379 -30.406 69.779 1.00 130.52 ? 27 LEU F CG 1 +ATOM 9735 C CD1 . LEU F 1 27 ? 74.412 -30.020 68.668 1.00 136.85 ? 27 LEU F CD1 1 +ATOM 9736 C CD2 . LEU F 1 27 ? 76.798 -30.502 69.233 1.00 134.87 ? 27 LEU F CD2 1 +ATOM 9737 N N . PRO F 1 28 ? 77.791 -28.323 72.936 1.00 125.16 ? 28 PRO F N 1 +ATOM 9738 C CA . PRO F 1 28 ? 78.385 -27.171 73.640 1.00 106.90 ? 28 PRO F CA 1 +ATOM 9739 C C . PRO F 1 28 ? 77.765 -25.874 73.192 1.00 143.14 ? 28 PRO F C 1 +ATOM 9740 O O . PRO F 1 28 ? 77.662 -25.638 71.996 1.00 219.12 ? 28 PRO F O 1 +ATOM 9741 C CB . PRO F 1 28 ? 79.843 -27.218 73.224 1.00 94.24 ? 28 PRO F CB 1 +ATOM 9742 C CG . PRO F 1 28 ? 79.856 -27.989 71.935 1.00 99.94 ? 28 PRO F CG 1 +ATOM 9743 C CD . PRO F 1 28 ? 78.767 -29.007 72.063 1.00 119.05 ? 28 PRO F CD 1 +ATOM 9744 N N . ALA F 1 29 ? 77.324 -25.052 74.135 1.00 170.24 ? 29 ALA F N 1 +ATOM 9745 C CA . ALA F 1 29 ? 76.471 -23.902 73.811 1.00 165.15 ? 29 ALA F CA 1 +ATOM 9746 C C . ALA F 1 29 ? 77.262 -22.761 73.132 1.00 162.81 ? 29 ALA F C 1 +ATOM 9747 O O . ALA F 1 29 ? 78.473 -22.594 73.363 1.00 132.43 ? 29 ALA F O 1 +ATOM 9748 C CB . ALA F 1 29 ? 75.765 -23.397 75.061 1.00 164.94 ? 29 ALA F CB 1 +ATOM 9749 N N . PRO F 1 30 ? 76.592 -22.013 72.234 1.00 146.21 ? 30 PRO F N 1 +ATOM 9750 C CA . PRO F 1 30 ? 77.199 -20.859 71.546 1.00 127.93 ? 30 PRO F CA 1 +ATOM 9751 C C . PRO F 1 30 ? 77.266 -19.628 72.450 1.00 100.86 ? 30 PRO F C 1 +ATOM 9752 O O . PRO F 1 30 ? 76.749 -19.675 73.577 1.00 115.21 ? 30 PRO F O 1 +ATOM 9753 C CB . PRO F 1 30 ? 76.219 -20.590 70.413 1.00 128.43 ? 30 PRO F CB 1 +ATOM 9754 C CG . PRO F 1 30 ? 74.900 -21.056 70.938 1.00 113.28 ? 30 PRO F CG 1 +ATOM 9755 C CD . PRO F 1 30 ? 75.179 -22.208 71.857 1.00 121.71 ? 30 PRO F CD 1 +ATOM 9756 N N . THR F 1 31 ? 77.836 -18.528 71.947 1.00 75.87 ? 31 THR F N 1 +ATOM 9757 C CA . THR F 1 31 ? 78.009 -17.298 72.754 1.00 94.85 ? 31 THR F CA 1 +ATOM 9758 C C . THR F 1 31 ? 76.685 -16.606 73.020 1.00 107.74 ? 31 THR F C 1 +ATOM 9759 O O . THR F 1 31 ? 76.523 -15.921 74.029 1.00 142.22 ? 31 THR F O 1 +ATOM 9760 C CB . THR F 1 31 ? 78.981 -16.272 72.113 1.00 106.23 ? 31 THR F CB 1 +ATOM 9761 O OG1 . THR F 1 31 ? 78.609 -16.015 70.758 1.00 115.57 ? 31 THR F OG1 1 +ATOM 9762 C CG2 . THR F 1 31 ? 80.425 -16.778 72.151 1.00 112.96 ? 31 THR F CG2 1 +ATOM 9763 N N . GLY F 1 32 ? 75.722 -16.823 72.132 1.00 133.93 ? 32 GLY F N 1 +ATOM 9764 C CA . GLY F 1 32 ? 74.326 -16.476 72.397 1.00 137.36 ? 32 GLY F CA 1 +ATOM 9765 C C . GLY F 1 32 ? 73.457 -17.356 71.531 1.00 118.03 ? 32 GLY F C 1 +ATOM 9766 O O . GLY F 1 32 ? 73.905 -17.801 70.473 1.00 130.54 ? 32 GLY F O 1 +ATOM 9767 N N . LYS F 1 33 ? 72.210 -17.582 71.933 1.00 103.19 ? 33 LYS F N 1 +ATOM 9768 C CA . LYS F 1 33 ? 71.274 -18.274 71.042 1.00 106.30 ? 33 LYS F CA 1 +ATOM 9769 C C . LYS F 1 33 ? 70.951 -17.449 69.768 1.00 127.04 ? 33 LYS F C 1 +ATOM 9770 O O . LYS F 1 33 ? 70.998 -16.213 69.792 1.00 104.98 ? 33 LYS F O 1 +ATOM 9771 C CB . LYS F 1 33 ? 69.985 -18.644 71.756 1.00 74.73 ? 33 LYS F CB 1 +ATOM 9772 C CG . LYS F 1 33 ? 70.038 -19.968 72.451 1.00 69.74 ? 33 LYS F CG 1 +ATOM 9773 C CD . LYS F 1 33 ? 68.804 -20.178 73.300 1.00 73.36 ? 33 LYS F CD 1 +ATOM 9774 C CE . LYS F 1 33 ? 69.090 -21.130 74.438 1.00 82.54 ? 33 LYS F CE 1 +ATOM 9775 N NZ . LYS F 1 33 ? 67.954 -21.234 75.373 1.00 92.50 ? 33 LYS F NZ 1 +ATOM 9776 N N . ILE F 1 34 ? 70.675 -18.137 68.659 1.00 131.41 ? 34 ILE F N 1 +ATOM 9777 C CA . ILE F 1 34 ? 70.450 -17.471 67.382 1.00 123.05 ? 34 ILE F CA 1 +ATOM 9778 C C . ILE F 1 34 ? 68.947 -17.540 67.072 1.00 137.70 ? 34 ILE F C 1 +ATOM 9779 O O . ILE F 1 34 ? 68.262 -18.501 67.461 1.00 99.99 ? 34 ILE F O 1 +ATOM 9780 C CB . ILE F 1 34 ? 71.343 -18.073 66.265 1.00 119.19 ? 34 ILE F CB 1 +ATOM 9781 C CG1 . ILE F 1 34 ? 72.817 -17.777 66.542 1.00 113.13 ? 34 ILE F CG1 1 +ATOM 9782 C CG2 . ILE F 1 34 ? 71.013 -17.500 64.896 1.00 141.86 ? 34 ILE F CG2 1 +ATOM 9783 C CD1 . ILE F 1 34 ? 73.654 -19.022 66.743 1.00 126.85 ? 34 ILE F CD1 1 +ATOM 9784 N N . PHE F 1 35 ? 68.429 -16.446 66.501 1.00 133.65 ? 35 PHE F N 1 +ATOM 9785 C CA . PHE F 1 35 ? 67.014 -16.297 66.164 1.00 122.86 ? 35 PHE F CA 1 +ATOM 9786 C C . PHE F 1 35 ? 66.700 -16.912 64.809 1.00 124.28 ? 35 PHE F C 1 +ATOM 9787 O O . PHE F 1 35 ? 67.354 -16.581 63.842 1.00 115.86 ? 35 PHE F O 1 +ATOM 9788 C CB . PHE F 1 35 ? 66.676 -14.823 66.071 1.00 96.70 ? 35 PHE F CB 1 +ATOM 9789 C CG . PHE F 1 35 ? 66.327 -14.192 67.381 1.00 107.10 ? 35 PHE F CG 1 +ATOM 9790 C CD1 . PHE F 1 35 ? 65.437 -14.810 68.276 1.00 124.91 ? 35 PHE F CD1 1 +ATOM 9791 C CD2 . PHE F 1 35 ? 66.755 -12.919 67.654 1.00 112.44 ? 35 PHE F CD2 1 +ATOM 9792 C CE1 . PHE F 1 35 ? 65.079 -14.204 69.467 1.00 103.01 ? 35 PHE F CE1 1 +ATOM 9793 C CE2 . PHE F 1 35 ? 66.364 -12.289 68.824 1.00 126.51 ? 35 PHE F CE2 1 +ATOM 9794 C CZ . PHE F 1 35 ? 65.530 -12.934 69.732 1.00 116.52 ? 35 PHE F CZ 1 +ATOM 9795 N N . VAL F 1 36 ? 65.731 -17.828 64.750 1.00 118.32 ? 36 VAL F N 1 +ATOM 9796 C CA . VAL F 1 36 ? 65.518 -18.614 63.539 1.00 97.86 ? 36 VAL F CA 1 +ATOM 9797 C C . VAL F 1 36 ? 64.058 -18.714 63.179 1.00 73.79 ? 36 VAL F C 1 +ATOM 9798 O O . VAL F 1 36 ? 63.196 -18.659 64.038 1.00 65.97 ? 36 VAL F O 1 +ATOM 9799 C CB . VAL F 1 36 ? 66.076 -20.053 63.657 1.00 110.86 ? 36 VAL F CB 1 +ATOM 9800 C CG1 . VAL F 1 36 ? 65.174 -20.937 64.525 1.00 92.16 ? 36 VAL F CG1 1 +ATOM 9801 C CG2 . VAL F 1 36 ? 66.237 -20.645 62.275 1.00 104.44 ? 36 VAL F CG2 1 +ATOM 9802 N N . SER F 1 37 ? 63.798 -18.844 61.891 1.00 69.43 ? 37 SER F N 1 +ATOM 9803 C CA . SER F 1 37 ? 62.444 -18.879 61.401 1.00 79.00 ? 37 SER F CA 1 +ATOM 9804 C C . SER F 1 37 ? 62.308 -20.127 60.594 1.00 72.19 ? 37 SER F C 1 +ATOM 9805 O O . SER F 1 37 ? 63.091 -20.362 59.686 1.00 42.16 ? 37 SER F O 1 +ATOM 9806 C CB . SER F 1 37 ? 62.154 -17.668 60.497 1.00 99.49 ? 37 SER F CB 1 +ATOM 9807 O OG . SER F 1 37 ? 61.977 -16.467 61.236 1.00 153.15 ? 37 SER F OG 1 +ATOM 9808 N N . VAL F 1 38 ? 61.246 -20.887 60.836 1.00 105.18 ? 38 VAL F N 1 +ATOM 9809 C CA . VAL F 1 38 ? 60.859 -21.955 59.884 1.00 111.60 ? 38 VAL F CA 1 +ATOM 9810 C C . VAL F 1 38 ? 59.431 -21.763 59.360 1.00 91.94 ? 38 VAL F C 1 +ATOM 9811 O O . VAL F 1 38 ? 58.488 -21.718 60.159 1.00 93.15 ? 38 VAL F O 1 +ATOM 9812 C CB . VAL F 1 38 ? 60.906 -23.345 60.536 1.00 117.77 ? 38 VAL F CB 1 +ATOM 9813 C CG1 . VAL F 1 38 ? 60.480 -24.387 59.532 1.00 107.35 ? 38 VAL F CG1 1 +ATOM 9814 C CG2 . VAL F 1 38 ? 62.297 -23.650 61.074 1.00 156.72 ? 38 VAL F CG2 1 +ATOM 9815 N N . TYR F 1 39 ? 59.301 -21.586 58.041 1.00 74.23 ? 39 TYR F N 1 +ATOM 9816 C CA . TYR F 1 39 ? 58.013 -21.271 57.406 1.00 82.72 ? 39 TYR F CA 1 +ATOM 9817 C C . TYR F 1 39 ? 57.346 -22.582 56.992 1.00 84.25 ? 39 TYR F C 1 +ATOM 9818 O O . TYR F 1 39 ? 56.220 -22.872 57.396 1.00 92.20 ? 39 TYR F O 1 +ATOM 9819 C CB . TYR F 1 39 ? 58.188 -20.303 56.197 1.00 79.20 ? 39 TYR F CB 1 +ATOM 9820 C CG . TYR F 1 39 ? 58.188 -18.798 56.560 1.00 72.86 ? 39 TYR F CG 1 +ATOM 9821 C CD1 . TYR F 1 39 ? 59.277 -18.214 57.183 1.00 73.16 ? 39 TYR F CD1 1 +ATOM 9822 C CD2 . TYR F 1 39 ? 57.054 -18.005 56.385 1.00 78.20 ? 39 TYR F CD2 1 +ATOM 9823 C CE1 . TYR F 1 39 ? 59.250 -16.880 57.605 1.00 70.04 ? 39 TYR F CE1 1 +ATOM 9824 C CE2 . TYR F 1 39 ? 57.011 -16.684 56.819 1.00 66.12 ? 39 TYR F CE2 1 +ATOM 9825 C CZ . TYR F 1 39 ? 58.121 -16.110 57.424 1.00 62.28 ? 39 TYR F CZ 1 +ATOM 9826 O OH . TYR F 1 39 ? 58.133 -14.759 57.759 1.00 34.82 ? 39 TYR F OH 1 +ATOM 9827 N N . ASN F 1 40 ? 58.078 -23.428 56.271 1.00 84.92 ? 40 ASN F N 1 +ATOM 9828 C CA . ASN F 1 40 ? 57.525 -24.719 55.841 1.00 84.52 ? 40 ASN F CA 1 +ATOM 9829 C C . ASN F 1 40 ? 58.558 -25.710 55.271 1.00 90.46 ? 40 ASN F C 1 +ATOM 9830 O O . ASN F 1 40 ? 59.386 -25.339 54.432 1.00 131.25 ? 40 ASN F O 1 +ATOM 9831 C CB . ASN F 1 40 ? 56.453 -24.468 54.787 1.00 89.33 ? 40 ASN F CB 1 +ATOM 9832 C CG . ASN F 1 40 ? 55.517 -25.639 54.624 1.00 111.35 ? 40 ASN F CG 1 +ATOM 9833 O OD1 . ASN F 1 40 ? 54.846 -26.076 55.580 1.00 158.82 ? 40 ASN F OD1 1 +ATOM 9834 N ND2 . ASN F 1 40 ? 55.480 -26.177 53.416 1.00 96.99 ? 40 ASN F ND2 1 +ATOM 9835 N N . ILE F 1 41 ? 58.505 -26.963 55.723 1.00 81.12 ? 41 ILE F N 1 +ATOM 9836 C CA . ILE F 1 41 ? 59.268 -28.053 55.090 1.00 92.77 ? 41 ILE F CA 1 +ATOM 9837 C C . ILE F 1 41 ? 58.342 -29.121 54.493 1.00 79.56 ? 41 ILE F C 1 +ATOM 9838 O O . ILE F 1 41 ? 57.521 -29.687 55.220 1.00 113.12 ? 41 ILE F O 1 +ATOM 9839 C CB . ILE F 1 41 ? 60.195 -28.742 56.093 1.00 99.76 ? 41 ILE F CB 1 +ATOM 9840 C CG1 . ILE F 1 41 ? 61.481 -27.934 56.297 1.00 114.35 ? 41 ILE F CG1 1 +ATOM 9841 C CG2 . ILE F 1 41 ? 60.611 -30.101 55.555 1.00 114.94 ? 41 ILE F CG2 1 +ATOM 9842 C CD1 . ILE F 1 41 ? 61.328 -26.647 57.072 1.00 135.45 ? 41 ILE F CD1 1 +ATOM 9843 N N . GLN F 1 42 ? 58.384 -29.304 53.172 1.00 62.01 ? 42 GLN F N 1 +ATOM 9844 C CA . GLN F 1 42 ? 57.303 -30.007 52.464 1.00 78.43 ? 42 GLN F CA 1 +ATOM 9845 C C . GLN F 1 42 ? 57.607 -31.459 52.321 1.00 60.94 ? 42 GLN F C 1 +ATOM 9846 O O . GLN F 1 42 ? 58.751 -31.847 52.377 1.00 60.83 ? 42 GLN F O 1 +ATOM 9847 C CB . GLN F 1 42 ? 57.049 -29.441 51.057 1.00 109.83 ? 42 GLN F CB 1 +ATOM 9848 C CG . GLN F 1 42 ? 56.480 -28.028 51.021 1.00 123.94 ? 42 GLN F CG 1 +ATOM 9849 C CD . GLN F 1 42 ? 57.407 -27.050 50.319 1.00 135.43 ? 42 GLN F CD 1 +ATOM 9850 O OE1 . GLN F 1 42 ? 57.362 -26.908 49.087 1.00 142.31 ? 42 GLN F OE1 1 +ATOM 9851 N NE2 . GLN F 1 42 ? 58.301 -26.411 51.087 1.00 113.14 ? 42 GLN F NE2 1 +ATOM 9852 N N . ASP F 1 43 ? 56.549 -32.262 52.177 1.00 69.88 ? 43 ASP F N 1 +ATOM 9853 C CA . ASP F 1 43 ? 56.666 -33.673 51.829 1.00 65.88 ? 43 ASP F CA 1 +ATOM 9854 C C . ASP F 1 43 ? 56.940 -33.834 50.333 1.00 65.48 ? 43 ASP F C 1 +ATOM 9855 O O . ASP F 1 43 ? 56.068 -34.323 49.598 1.00 74.55 ? 43 ASP F O 1 +ATOM 9856 C CB . ASP F 1 43 ? 55.386 -34.420 52.221 1.00 69.51 ? 43 ASP F CB 1 +ATOM 9857 C CG . ASP F 1 43 ? 55.524 -35.946 52.066 1.00 84.18 ? 43 ASP F CG 1 +ATOM 9858 O OD1 . ASP F 1 43 ? 56.519 -36.493 52.565 1.00 77.29 ? 43 ASP F OD1 1 +ATOM 9859 O OD2 . ASP F 1 43 ? 54.649 -36.603 51.448 1.00 98.08 ? 43 ASP F OD2 1 +ATOM 9860 N N . GLU F 1 44 ? 58.094 -33.336 49.872 1.00 57.35 ? 44 GLU F N 1 +ATOM 9861 C CA . GLU F 1 44 ? 58.421 -33.310 48.443 1.00 59.87 ? 44 GLU F CA 1 +ATOM 9862 C C . GLU F 1 44 ? 58.693 -34.735 47.930 1.00 58.96 ? 44 GLU F C 1 +ATOM 9863 O O . GLU F 1 44 ? 59.174 -34.915 46.789 1.00 61.53 ? 44 GLU F O 1 +ATOM 9864 C CB . GLU F 1 44 ? 59.619 -32.392 48.158 1.00 60.21 ? 44 GLU F CB 1 +ATOM 9865 C CG . GLU F 1 44 ? 59.285 -30.924 47.896 1.00 83.74 ? 44 GLU F CG 1 +ATOM 9866 C CD . GLU F 1 44 ? 60.521 -30.021 47.661 1.00 127.96 ? 44 GLU F CD 1 +ATOM 9867 O OE1 . GLU F 1 44 ? 61.459 -30.386 46.899 1.00 175.96 ? 44 GLU F OE1 1 +ATOM 9868 O OE2 . GLU F 1 44 ? 60.553 -28.886 48.201 1.00 158.90 ? 44 GLU F OE2 1 +ATOM 9869 N N . THR F 1 45 ? 58.281 -35.738 48.714 1.00 57.17 ? 45 THR F N 1 +ATOM 9870 C CA . THR F 1 45 ? 58.603 -37.133 48.415 1.00 71.52 ? 45 THR F CA 1 +ATOM 9871 C C . THR F 1 45 ? 57.814 -37.728 47.248 1.00 89.01 ? 45 THR F C 1 +ATOM 9872 O O . THR F 1 45 ? 58.358 -38.493 46.444 1.00 70.33 ? 45 THR F O 1 +ATOM 9873 C CB . THR F 1 45 ? 58.474 -38.021 49.664 1.00 90.46 ? 45 THR F CB 1 +ATOM 9874 O OG1 . THR F 1 45 ? 59.098 -39.289 49.429 1.00 163.83 ? 45 THR F OG1 1 +ATOM 9875 C CG2 . THR F 1 45 ? 57.012 -38.279 50.074 1.00 76.80 ? 45 THR F CG2 1 +ATOM 9876 N N . GLY F 1 46 ? 56.513 -37.433 47.172 1.00 102.44 ? 46 GLY F N 1 +ATOM 9877 C CA . GLY F 1 46 ? 55.673 -37.869 46.020 1.00 82.72 ? 46 GLY F CA 1 +ATOM 9878 C C . GLY F 1 46 ? 55.021 -39.249 46.183 1.00 62.70 ? 46 GLY F C 1 +ATOM 9879 O O . GLY F 1 46 ? 54.607 -39.905 45.236 1.00 40.42 ? 46 GLY F O 1 +ATOM 9880 N N . GLN F 1 47 ? 54.862 -39.672 47.413 1.00 61.59 ? 47 GLN F N 1 +ATOM 9881 C CA . GLN F 1 47 ? 54.691 -41.061 47.612 1.00 67.59 ? 47 GLN F CA 1 +ATOM 9882 C C . GLN F 1 47 ? 53.588 -41.333 48.591 1.00 72.62 ? 47 GLN F C 1 +ATOM 9883 O O . GLN F 1 47 ? 53.451 -40.657 49.612 1.00 52.14 ? 47 GLN F O 1 +ATOM 9884 C CB . GLN F 1 47 ? 55.995 -41.667 48.054 1.00 71.77 ? 47 GLN F CB 1 +ATOM 9885 C CG . GLN F 1 47 ? 57.083 -41.661 46.961 1.00 73.88 ? 47 GLN F CG 1 +ATOM 9886 C CD . GLN F 1 47 ? 56.626 -42.235 45.661 1.00 61.07 ? 47 GLN F CD 1 +ATOM 9887 O OE1 . GLN F 1 47 ? 56.402 -43.434 45.557 1.00 82.54 ? 47 GLN F OE1 1 +ATOM 9888 N NE2 . GLN F 1 47 ? 56.436 -41.397 44.686 1.00 62.78 ? 47 GLN F NE2 1 +ATOM 9889 N N . PHE F 1 48 ? 52.784 -42.323 48.216 1.00 91.79 ? 48 PHE F N 1 +ATOM 9890 C CA . PHE F 1 48 ? 51.654 -42.785 49.013 1.00 84.14 ? 48 PHE F CA 1 +ATOM 9891 C C . PHE F 1 48 ? 51.733 -44.281 49.243 1.00 94.90 ? 48 PHE F C 1 +ATOM 9892 O O . PHE F 1 48 ? 52.582 -44.996 48.660 1.00 99.77 ? 48 PHE F O 1 +ATOM 9893 C CB . PHE F 1 48 ? 50.347 -42.529 48.298 1.00 84.83 ? 48 PHE F CB 1 +ATOM 9894 C CG . PHE F 1 48 ? 50.042 -41.104 48.128 1.00 82.71 ? 48 PHE F CG 1 +ATOM 9895 C CD1 . PHE F 1 48 ? 50.709 -40.377 47.144 1.00 79.31 ? 48 PHE F CD1 1 +ATOM 9896 C CD2 . PHE F 1 48 ? 49.090 -40.495 48.927 1.00 58.65 ? 48 PHE F CD2 1 +ATOM 9897 C CE1 . PHE F 1 48 ? 50.495 -39.035 47.022 1.00 76.02 ? 48 PHE F CE1 1 +ATOM 9898 C CE2 . PHE F 1 48 ? 48.838 -39.166 48.786 1.00 52.53 ? 48 PHE F CE2 1 +ATOM 9899 C CZ . PHE F 1 48 ? 49.568 -38.427 47.857 1.00 72.81 ? 48 PHE F CZ 1 +ATOM 9900 N N . LYS F 1 49 ? 50.888 -44.744 50.158 1.00 94.75 ? 49 LYS F N 1 +ATOM 9901 C CA . LYS F 1 49 ? 50.981 -46.118 50.643 1.00 112.67 ? 49 LYS F CA 1 +ATOM 9902 C C . LYS F 1 49 ? 50.269 -46.981 49.651 1.00 118.89 ? 49 LYS F C 1 +ATOM 9903 O O . LYS F 1 49 ? 49.313 -46.528 49.016 1.00 155.36 ? 49 LYS F O 1 +ATOM 9904 C CB . LYS F 1 49 ? 50.382 -46.273 52.048 1.00 113.91 ? 49 LYS F CB 1 +ATOM 9905 C CG . LYS F 1 49 ? 51.227 -45.574 53.119 1.00 120.19 ? 49 LYS F CG 1 +ATOM 9906 C CD . LYS F 1 49 ? 50.853 -45.831 54.567 1.00 119.63 ? 49 LYS F CD 1 +ATOM 9907 C CE . LYS F 1 49 ? 51.923 -45.163 55.436 1.00 125.03 ? 49 LYS F CE 1 +ATOM 9908 N NZ . LYS F 1 49 ? 51.756 -45.341 56.903 1.00 156.56 ? 49 LYS F NZ 1 +ATOM 9909 N N . PRO F 1 50 ? 50.773 -48.210 49.467 1.00 110.08 ? 50 PRO F N 1 +ATOM 9910 C CA . PRO F 1 50 ? 50.176 -49.131 48.523 1.00 113.99 ? 50 PRO F CA 1 +ATOM 9911 C C . PRO F 1 50 ? 48.917 -49.800 49.090 1.00 103.48 ? 50 PRO F C 1 +ATOM 9912 O O . PRO F 1 50 ? 48.652 -49.734 50.307 1.00 57.60 ? 50 PRO F O 1 +ATOM 9913 C CB . PRO F 1 50 ? 51.298 -50.156 48.290 1.00 121.22 ? 50 PRO F CB 1 +ATOM 9914 C CG . PRO F 1 50 ? 52.097 -50.144 49.551 1.00 98.54 ? 50 PRO F CG 1 +ATOM 9915 C CD . PRO F 1 50 ? 52.018 -48.741 50.059 1.00 97.30 ? 50 PRO F CD 1 +ATOM 9916 N N . TYR F 1 51 ? 48.182 -50.474 48.210 1.00 91.58 ? 51 TYR F N 1 +ATOM 9917 C CA . TYR F 1 51 ? 47.094 -51.315 48.647 1.00 91.33 ? 51 TYR F CA 1 +ATOM 9918 C C . TYR F 1 51 ? 47.560 -52.250 49.748 1.00 98.57 ? 51 TYR F C 1 +ATOM 9919 O O . TYR F 1 51 ? 48.657 -52.820 49.651 1.00 129.89 ? 51 TYR F O 1 +ATOM 9920 C CB . TYR F 1 51 ? 46.551 -52.138 47.487 1.00 95.35 ? 51 TYR F CB 1 +ATOM 9921 C CG . TYR F 1 51 ? 45.207 -52.750 47.823 1.00 103.08 ? 51 TYR F CG 1 +ATOM 9922 C CD1 . TYR F 1 51 ? 44.044 -52.029 47.634 1.00 105.45 ? 51 TYR F CD1 1 +ATOM 9923 C CD2 . TYR F 1 51 ? 45.100 -54.035 48.334 1.00 109.65 ? 51 TYR F CD2 1 +ATOM 9924 C CE1 . TYR F 1 51 ? 42.812 -52.560 47.935 1.00 96.04 ? 51 TYR F CE1 1 +ATOM 9925 C CE2 . TYR F 1 51 ? 43.855 -54.588 48.612 1.00 101.66 ? 51 TYR F CE2 1 +ATOM 9926 C CZ . TYR F 1 51 ? 42.724 -53.818 48.432 1.00 92.45 ? 51 TYR F CZ 1 +ATOM 9927 O OH . TYR F 1 51 ? 41.470 -54.293 48.710 1.00 127.80 ? 51 TYR F OH 1 +ATOM 9928 N N . PRO F 1 52 ? 46.744 -52.423 50.809 1.00 107.76 ? 52 PRO F N 1 +ATOM 9929 C CA . PRO F 1 52 ? 45.379 -51.940 51.031 1.00 106.58 ? 52 PRO F CA 1 +ATOM 9930 C C . PRO F 1 52 ? 45.214 -50.591 51.718 1.00 134.32 ? 52 PRO F C 1 +ATOM 9931 O O . PRO F 1 52 ? 44.128 -50.328 52.252 1.00 146.44 ? 52 PRO F O 1 +ATOM 9932 C CB . PRO F 1 52 ? 44.788 -53.028 51.920 1.00 108.01 ? 52 PRO F CB 1 +ATOM 9933 C CG . PRO F 1 52 ? 45.949 -53.463 52.768 1.00 120.00 ? 52 PRO F CG 1 +ATOM 9934 C CD . PRO F 1 52 ? 47.173 -53.345 51.886 1.00 122.78 ? 52 PRO F CD 1 +ATOM 9935 N N . ALA F 1 53 ? 46.256 -49.752 51.757 1.00 143.90 ? 53 ALA F N 1 +ATOM 9936 C CA . ALA F 1 53 ? 46.119 -48.432 52.396 1.00 152.93 ? 53 ALA F CA 1 +ATOM 9937 C C . ALA F 1 53 ? 45.093 -47.626 51.625 1.00 163.78 ? 53 ALA F C 1 +ATOM 9938 O O . ALA F 1 53 ? 44.810 -47.909 50.458 1.00 158.93 ? 53 ALA F O 1 +ATOM 9939 C CB . ALA F 1 53 ? 47.452 -47.683 52.468 1.00 122.09 ? 53 ALA F CB 1 +ATOM 9940 N N . SER F 1 54 ? 44.545 -46.598 52.263 1.00 192.31 ? 54 SER F N 1 +ATOM 9941 C CA . SER F 1 54 ? 43.783 -45.626 51.499 1.00 172.02 ? 54 SER F CA 1 +ATOM 9942 C C . SER F 1 54 ? 44.675 -45.052 50.404 1.00 165.45 ? 54 SER F C 1 +ATOM 9943 O O . SER F 1 54 ? 45.894 -44.806 50.595 1.00 258.48 ? 54 SER F O 1 +ATOM 9944 C CB . SER F 1 54 ? 43.246 -44.497 52.376 1.00 187.88 ? 54 SER F CB 1 +ATOM 9945 O OG . SER F 1 54 ? 42.943 -43.333 51.616 1.00 164.78 ? 54 SER F OG 1 +ATOM 9946 N N . ASN F 1 55 ? 44.063 -44.840 49.248 1.00 105.87 ? 55 ASN F N 1 +ATOM 9947 C CA . ASN F 1 55 ? 44.741 -44.226 48.120 1.00 81.29 ? 55 ASN F CA 1 +ATOM 9948 C C . ASN F 1 55 ? 45.457 -42.935 48.518 1.00 85.88 ? 55 ASN F C 1 +ATOM 9949 O O . ASN F 1 55 ? 46.521 -42.558 47.963 1.00 111.63 ? 55 ASN F O 1 +ATOM 9950 C CB . ASN F 1 55 ? 43.711 -43.940 47.054 1.00 59.63 ? 55 ASN F CB 1 +ATOM 9951 C CG . ASN F 1 55 ? 44.325 -43.752 45.710 1.00 76.97 ? 55 ASN F CG 1 +ATOM 9952 O OD1 . ASN F 1 55 ? 45.506 -44.038 45.462 1.00 113.53 ? 55 ASN F OD1 1 +ATOM 9953 N ND2 . ASN F 1 55 ? 43.532 -43.251 44.818 1.00 79.60 ? 55 ASN F ND2 1 +ATOM 9954 N N . PHE F 1 56 ? 44.911 -42.291 49.554 1.00 83.71 ? 56 PHE F N 1 +ATOM 9955 C CA . PHE F 1 56 ? 45.326 -40.952 49.967 1.00 87.76 ? 56 PHE F CA 1 +ATOM 9956 C C . PHE F 1 56 ? 46.292 -40.938 51.142 1.00 99.55 ? 56 PHE F C 1 +ATOM 9957 O O . PHE F 1 56 ? 46.688 -39.876 51.621 1.00 118.24 ? 56 PHE F O 1 +ATOM 9958 C CB . PHE F 1 56 ? 44.098 -40.137 50.366 1.00 79.32 ? 56 PHE F CB 1 +ATOM 9959 C CG . PHE F 1 56 ? 43.051 -40.059 49.282 1.00 71.06 ? 56 PHE F CG 1 +ATOM 9960 C CD1 . PHE F 1 56 ? 43.327 -39.493 48.030 1.00 74.82 ? 56 PHE F CD1 1 +ATOM 9961 C CD2 . PHE F 1 56 ? 41.826 -40.586 49.487 1.00 74.17 ? 56 PHE F CD2 1 +ATOM 9962 C CE1 . PHE F 1 56 ? 42.397 -39.516 47.001 1.00 58.80 ? 56 PHE F CE1 1 +ATOM 9963 C CE2 . PHE F 1 56 ? 40.852 -40.504 48.497 1.00 77.99 ? 56 PHE F CE2 1 +ATOM 9964 C CZ . PHE F 1 56 ? 41.144 -39.987 47.242 1.00 54.94 ? 56 PHE F CZ 1 +ATOM 9965 N N . SER F 1 57 ? 46.632 -42.102 51.665 1.00 120.93 ? 57 SER F N 1 +ATOM 9966 C CA . SER F 1 57 ? 47.577 -42.160 52.783 1.00 105.31 ? 57 SER F CA 1 +ATOM 9967 C C . SER F 1 57 ? 48.999 -41.908 52.272 1.00 99.29 ? 57 SER F C 1 +ATOM 9968 O O . SER F 1 57 ? 49.561 -42.662 51.469 1.00 64.58 ? 57 SER F O 1 +ATOM 9969 C CB . SER F 1 57 ? 47.484 -43.510 53.498 1.00 132.93 ? 57 SER F CB 1 +ATOM 9970 O OG . SER F 1 57 ? 46.299 -43.577 54.263 1.00 153.63 ? 57 SER F OG 1 +ATOM 9971 N N . THR F 1 58 ? 49.592 -40.825 52.738 1.00 98.40 ? 58 THR F N 1 +ATOM 9972 C CA . THR F 1 58 ? 50.939 -40.472 52.311 1.00 94.45 ? 58 THR F CA 1 +ATOM 9973 C C . THR F 1 58 ? 51.920 -41.439 52.899 1.00 84.20 ? 58 THR F C 1 +ATOM 9974 O O . THR F 1 58 ? 51.755 -41.922 54.023 1.00 71.18 ? 58 THR F O 1 +ATOM 9975 C CB . THR F 1 58 ? 51.300 -39.050 52.773 1.00 102.59 ? 58 THR F CB 1 +ATOM 9976 O OG1 . THR F 1 58 ? 51.232 -38.958 54.204 1.00 136.14 ? 58 THR F OG1 1 +ATOM 9977 C CG2 . THR F 1 58 ? 50.327 -38.076 52.200 1.00 127.49 ? 58 THR F CG2 1 +ATOM 9978 N N . ALA F 1 59 ? 53.050 -41.593 52.250 1.00 108.20 ? 59 ALA F N 1 +ATOM 9979 C CA . ALA F 1 59 ? 54.041 -42.492 52.817 1.00 143.09 ? 59 ALA F CA 1 +ATOM 9980 C C . ALA F 1 59 ? 54.820 -41.870 53.998 1.00 159.93 ? 59 ALA F C 1 +ATOM 9981 O O . ALA F 1 59 ? 55.372 -42.588 54.837 1.00 90.77 ? 59 ALA F O 1 +ATOM 9982 C CB . ALA F 1 59 ? 54.999 -42.928 51.754 1.00 122.99 ? 59 ALA F CB 1 +ATOM 9983 N N . VAL F 1 60 ? 54.803 -40.534 54.082 1.00 147.37 ? 60 VAL F N 1 +ATOM 9984 C CA . VAL F 1 60 ? 55.575 -39.789 55.074 1.00 113.34 ? 60 VAL F CA 1 +ATOM 9985 C C . VAL F 1 60 ? 54.679 -38.755 55.762 1.00 90.28 ? 60 VAL F C 1 +ATOM 9986 O O . VAL F 1 60 ? 53.848 -38.136 55.108 1.00 96.57 ? 60 VAL F O 1 +ATOM 9987 C CB . VAL F 1 60 ? 56.733 -39.072 54.372 1.00 114.71 ? 60 VAL F CB 1 +ATOM 9988 C CG1 . VAL F 1 60 ? 57.575 -38.257 55.358 1.00 129.58 ? 60 VAL F CG1 1 +ATOM 9989 C CG2 . VAL F 1 60 ? 57.590 -40.078 53.622 1.00 105.35 ? 60 VAL F CG2 1 +ATOM 9990 N N . PRO F 1 61 ? 54.839 -38.558 57.087 1.00 109.42 ? 61 PRO F N 1 +ATOM 9991 C CA . PRO F 1 61 ? 54.006 -37.571 57.767 1.00 138.55 ? 61 PRO F CA 1 +ATOM 9992 C C . PRO F 1 61 ? 54.291 -36.150 57.304 1.00 159.10 ? 61 PRO F C 1 +ATOM 9993 O O . PRO F 1 61 ? 55.436 -35.817 56.981 1.00 117.41 ? 61 PRO F O 1 +ATOM 9994 C CB . PRO F 1 61 ? 54.384 -37.728 59.245 1.00 136.90 ? 61 PRO F CB 1 +ATOM 9995 C CG . PRO F 1 61 ? 55.716 -38.369 59.229 1.00 138.27 ? 61 PRO F CG 1 +ATOM 9996 C CD . PRO F 1 61 ? 55.700 -39.278 58.036 1.00 139.48 ? 61 PRO F CD 1 +ATOM 9997 N N . GLN F 1 62 ? 53.233 -35.338 57.254 1.00 172.95 ? 62 GLN F N 1 +ATOM 9998 C CA . GLN F 1 62 ? 53.307 -33.989 56.694 1.00 145.87 ? 62 GLN F CA 1 +ATOM 9999 C C . GLN F 1 62 ? 53.714 -33.001 57.760 1.00 157.44 ? 62 GLN F C 1 +ATOM 10000 O O . GLN F 1 62 ? 53.253 -31.872 57.768 1.00 85.79 ? 62 GLN F O 1 +ATOM 10001 C CB . GLN F 1 62 ? 51.951 -33.575 56.124 1.00 132.46 ? 62 GLN F CB 1 +ATOM 10002 C CG . GLN F 1 62 ? 51.354 -34.573 55.157 1.00 113.24 ? 62 GLN F CG 1 +ATOM 10003 C CD . GLN F 1 62 ? 52.312 -34.812 54.012 1.00 94.20 ? 62 GLN F CD 1 +ATOM 10004 O OE1 . GLN F 1 62 ? 52.338 -34.055 53.059 1.00 102.59 ? 62 GLN F OE1 1 +ATOM 10005 N NE2 . GLN F 1 62 ? 53.017 -35.916 54.052 1.00 123.38 ? 62 GLN F NE2 1 +ATOM 10006 N N . SER F 1 63 ? 54.560 -33.450 58.680 1.00 174.33 ? 63 SER F N 1 +ATOM 10007 C CA . SER F 1 63 ? 54.729 -32.772 59.956 1.00 153.52 ? 63 SER F CA 1 +ATOM 10008 C C . SER F 1 63 ? 56.173 -32.288 60.152 1.00 130.53 ? 63 SER F C 1 +ATOM 10009 O O . SER F 1 63 ? 56.552 -31.864 61.251 1.00 136.51 ? 63 SER F O 1 +ATOM 10010 C CB . SER F 1 63 ? 54.273 -33.699 61.103 1.00 132.20 ? 63 SER F CB 1 +ATOM 10011 O OG . SER F 1 63 ? 55.049 -34.891 61.204 1.00 106.92 ? 63 SER F OG 1 +ATOM 10012 N N . ALA F 1 64 ? 56.973 -32.388 59.088 1.00 78.10 ? 64 ALA F N 1 +ATOM 10013 C CA . ALA F 1 64 ? 58.399 -32.149 59.164 1.00 71.61 ? 64 ALA F CA 1 +ATOM 10014 C C . ALA F 1 64 ? 58.753 -30.756 59.707 1.00 84.15 ? 64 ALA F C 1 +ATOM 10015 O O . ALA F 1 64 ? 59.699 -30.613 60.522 1.00 114.92 ? 64 ALA F O 1 +ATOM 10016 C CB . ALA F 1 64 ? 58.999 -32.346 57.794 1.00 57.57 ? 64 ALA F CB 1 +ATOM 10017 N N . THR F 1 65 ? 57.961 -29.768 59.299 1.00 79.60 ? 65 THR F N 1 +ATOM 10018 C CA . THR F 1 65 ? 58.124 -28.381 59.709 1.00 82.64 ? 65 THR F CA 1 +ATOM 10019 C C . THR F 1 65 ? 58.181 -28.254 61.249 1.00 84.30 ? 65 THR F C 1 +ATOM 10020 O O . THR F 1 65 ? 59.120 -27.652 61.816 1.00 77.96 ? 65 THR F O 1 +ATOM 10021 C CB . THR F 1 65 ? 56.969 -27.521 59.136 1.00 98.31 ? 65 THR F CB 1 +ATOM 10022 O OG1 . THR F 1 65 ? 57.018 -26.173 59.671 1.00 183.62 ? 65 THR F OG1 1 +ATOM 10023 C CG2 . THR F 1 65 ? 55.660 -28.212 59.509 1.00 79.61 ? 65 THR F CG2 1 +ATOM 10024 N N . ALA F 1 66 ? 57.238 -28.891 61.953 1.00 85.33 ? 66 ALA F N 1 +ATOM 10025 C CA . ALA F 1 66 ? 57.179 -28.784 63.429 1.00 94.50 ? 66 ALA F CA 1 +ATOM 10026 C C . ALA F 1 66 ? 58.305 -29.571 64.127 1.00 94.11 ? 66 ALA F C 1 +ATOM 10027 O O . ALA F 1 66 ? 58.867 -29.125 65.136 1.00 85.19 ? 66 ALA F O 1 +ATOM 10028 C CB . ALA F 1 66 ? 55.837 -29.253 63.927 1.00 94.30 ? 66 ALA F CB 1 +ATOM 10029 N N . MET F 1 67 ? 58.703 -30.678 63.507 1.00 80.80 ? 67 MET F N 1 +ATOM 10030 C CA . MET F 1 67 ? 59.842 -31.439 63.988 1.00 77.97 ? 67 MET F CA 1 +ATOM 10031 C C . MET F 1 67 ? 61.123 -30.601 63.931 1.00 53.46 ? 67 MET F C 1 +ATOM 10032 O O . MET F 1 67 ? 61.962 -30.673 64.836 1.00 67.80 ? 67 MET F O 1 +ATOM 10033 C CB . MET F 1 67 ? 60.017 -32.746 63.170 1.00 93.34 ? 67 MET F CB 1 +ATOM 10034 C CG . MET F 1 67 ? 58.931 -33.806 63.386 1.00 100.00 ? 67 MET F CG 1 +ATOM 10035 S SD . MET F 1 67 ? 59.053 -35.141 62.150 1.00 69.37 ? 67 MET F SD 1 +ATOM 10036 C CE . MET F 1 67 ? 57.791 -36.263 62.752 1.00 100.17 ? 67 MET F CE 1 +ATOM 10037 N N . LEU F 1 68 ? 61.344 -29.950 62.801 1.00 38.72 ? 68 LEU F N 1 +ATOM 10038 C CA . LEU F 1 68 ? 62.531 -29.157 62.643 1.00 41.67 ? 68 LEU F CA 1 +ATOM 10039 C C . LEU F 1 68 ? 62.568 -28.044 63.659 1.00 47.79 ? 68 LEU F C 1 +ATOM 10040 O O . LEU F 1 68 ? 63.602 -27.764 64.234 1.00 77.29 ? 68 LEU F O 1 +ATOM 10041 C CB . LEU F 1 68 ? 62.603 -28.531 61.261 1.00 58.86 ? 68 LEU F CB 1 +ATOM 10042 C CG . LEU F 1 68 ? 63.713 -27.447 61.109 1.00 57.45 ? 68 LEU F CG 1 +ATOM 10043 C CD1 . LEU F 1 68 ? 65.069 -28.118 61.215 1.00 75.78 ? 68 LEU F CD1 1 +ATOM 10044 C CD2 . LEU F 1 68 ? 63.618 -26.704 59.797 1.00 57.05 ? 68 LEU F CD2 1 +ATOM 10045 N N . VAL F 1 69 ? 61.448 -27.355 63.861 1.00 71.71 ? 69 VAL F N 1 +ATOM 10046 C CA . VAL F 1 69 ? 61.377 -26.239 64.841 1.00 69.24 ? 69 VAL F CA 1 +ATOM 10047 C C . VAL F 1 69 ? 61.722 -26.773 66.229 1.00 84.17 ? 69 VAL F C 1 +ATOM 10048 O O . VAL F 1 69 ? 62.504 -26.168 66.963 1.00 76.11 ? 69 VAL F O 1 +ATOM 10049 C CB . VAL F 1 69 ? 59.978 -25.547 64.901 1.00 54.43 ? 69 VAL F CB 1 +ATOM 10050 C CG1 . VAL F 1 69 ? 59.937 -24.568 66.041 1.00 41.36 ? 69 VAL F CG1 1 +ATOM 10051 C CG2 . VAL F 1 69 ? 59.639 -24.832 63.585 1.00 57.13 ? 69 VAL F CG2 1 +ATOM 10052 N N . THR F 1 70 ? 61.181 -27.945 66.546 1.00 106.99 ? 70 THR F N 1 +ATOM 10053 C CA . THR F 1 70 ? 61.433 -28.582 67.836 1.00 116.30 ? 70 THR F CA 1 +ATOM 10054 C C . THR F 1 70 ? 62.903 -28.956 68.004 1.00 91.19 ? 70 THR F C 1 +ATOM 10055 O O . THR F 1 70 ? 63.515 -28.689 69.034 1.00 105.58 ? 70 THR F O 1 +ATOM 10056 C CB . THR F 1 70 ? 60.550 -29.828 68.007 1.00 103.13 ? 70 THR F CB 1 +ATOM 10057 O OG1 . THR F 1 70 ? 59.177 -29.436 67.827 1.00 151.02 ? 70 THR F OG1 1 +ATOM 10058 C CG2 . THR F 1 70 ? 60.756 -30.440 69.406 1.00 79.57 ? 70 THR F CG2 1 +ATOM 10059 N N . ALA F 1 71 ? 63.481 -29.508 66.955 1.00 72.73 ? 71 ALA F N 1 +ATOM 10060 C CA . ALA F 1 71 ? 64.887 -29.851 66.983 1.00 74.44 ? 71 ALA F CA 1 +ATOM 10061 C C . ALA F 1 71 ? 65.734 -28.603 67.178 1.00 61.82 ? 71 ALA F C 1 +ATOM 10062 O O . ALA F 1 71 ? 66.747 -28.623 67.890 1.00 78.32 ? 71 ALA F O 1 +ATOM 10063 C CB . ALA F 1 71 ? 65.283 -30.619 65.704 1.00 84.52 ? 71 ALA F CB 1 +ATOM 10064 N N . LEU F 1 72 ? 65.377 -27.547 66.470 1.00 67.05 ? 72 LEU F N 1 +ATOM 10065 C CA . LEU F 1 72 ? 66.133 -26.293 66.535 1.00 92.60 ? 72 LEU F CA 1 +ATOM 10066 C C . LEU F 1 72 ? 66.077 -25.741 67.937 1.00 101.65 ? 72 LEU F C 1 +ATOM 10067 O O . LEU F 1 72 ? 66.973 -25.002 68.351 1.00 108.67 ? 72 LEU F O 1 +ATOM 10068 C CB . LEU F 1 72 ? 65.573 -25.249 65.553 1.00 99.16 ? 72 LEU F CB 1 +ATOM 10069 C CG . LEU F 1 72 ? 65.816 -25.550 64.072 1.00 96.82 ? 72 LEU F CG 1 +ATOM 10070 C CD1 . LEU F 1 72 ? 64.868 -24.718 63.238 1.00 77.80 ? 72 LEU F CD1 1 +ATOM 10071 C CD2 . LEU F 1 72 ? 67.260 -25.308 63.664 1.00 86.48 ? 72 LEU F CD2 1 +ATOM 10072 N N . LYS F 1 73 ? 65.017 -26.076 68.669 1.00 96.14 ? 73 LYS F N 1 +ATOM 10073 C CA . LYS F 1 73 ? 64.888 -25.594 70.050 1.00 111.39 ? 73 LYS F CA 1 +ATOM 10074 C C . LYS F 1 73 ? 65.677 -26.464 71.021 1.00 107.55 ? 73 LYS F C 1 +ATOM 10075 O O . LYS F 1 73 ? 66.351 -25.943 71.897 1.00 126.60 ? 73 LYS F O 1 +ATOM 10076 C CB . LYS F 1 73 ? 63.420 -25.521 70.487 1.00 91.87 ? 73 LYS F CB 1 +ATOM 10077 C CG . LYS F 1 73 ? 63.182 -24.738 71.788 1.00 67.79 ? 73 LYS F CG 1 +ATOM 10078 C CD . LYS F 1 73 ? 61.696 -24.714 72.166 1.00 65.10 ? 73 LYS F CD 1 +ATOM 10079 C CE . LYS F 1 73 ? 61.477 -24.613 73.667 1.00 64.52 ? 73 LYS F CE 1 +ATOM 10080 N NZ . LYS F 1 73 ? 60.838 -23.345 74.088 1.00 56.39 ? 73 LYS F NZ 1 +ATOM 10081 N N . ASP F 1 74 ? 65.552 -27.775 70.877 1.00 100.71 ? 74 ASP F N 1 +ATOM 10082 C CA . ASP F 1 74 ? 66.170 -28.701 71.802 1.00 112.80 ? 74 ASP F CA 1 +ATOM 10083 C C . ASP F 1 74 ? 67.679 -28.509 71.810 1.00 97.34 ? 74 ASP F C 1 +ATOM 10084 O O . ASP F 1 74 ? 68.337 -28.828 72.804 1.00 121.69 ? 74 ASP F O 1 +ATOM 10085 C CB . ASP F 1 74 ? 65.796 -30.161 71.442 1.00 119.87 ? 74 ASP F CB 1 +ATOM 10086 C CG . ASP F 1 74 ? 64.320 -30.490 71.719 1.00 113.78 ? 74 ASP F CG 1 +ATOM 10087 O OD1 . ASP F 1 74 ? 63.691 -29.869 72.622 1.00 131.58 ? 74 ASP F OD1 1 +ATOM 10088 O OD2 . ASP F 1 74 ? 63.778 -31.372 71.018 1.00 87.43 ? 74 ASP F OD2 1 +ATOM 10089 N N . SER F 1 75 ? 68.229 -28.103 70.668 1.00 83.83 ? 75 SER F N 1 +ATOM 10090 C CA . SER F 1 75 ? 69.691 -27.982 70.500 1.00 97.85 ? 75 SER F CA 1 +ATOM 10091 C C . SER F 1 75 ? 70.293 -26.954 71.442 1.00 88.99 ? 75 SER F C 1 +ATOM 10092 O O . SER F 1 75 ? 71.483 -26.996 71.734 1.00 74.85 ? 75 SER F O 1 +ATOM 10093 C CB . SER F 1 75 ? 70.049 -27.614 69.051 1.00 103.95 ? 75 SER F CB 1 +ATOM 10094 O OG . SER F 1 75 ? 69.971 -26.219 68.838 1.00 107.44 ? 75 SER F OG 1 +ATOM 10095 N N . ARG F 1 76 ? 69.461 -26.005 71.873 1.00 99.39 ? 76 ARG F N 1 +ATOM 10096 C CA . ARG F 1 76 ? 69.883 -24.864 72.698 1.00 93.75 ? 76 ARG F CA 1 +ATOM 10097 C C . ARG F 1 76 ? 70.934 -24.036 71.990 1.00 68.66 ? 76 ARG F C 1 +ATOM 10098 O O . ARG F 1 76 ? 71.833 -23.476 72.603 1.00 56.10 ? 76 ARG F O 1 +ATOM 10099 C CB . ARG F 1 76 ? 70.418 -25.340 74.033 1.00 122.43 ? 76 ARG F CB 1 +ATOM 10100 C CG . ARG F 1 76 ? 69.414 -26.114 74.872 1.00 135.91 ? 76 ARG F CG 1 +ATOM 10101 C CD . ARG F 1 76 ? 70.044 -26.507 76.206 1.00 139.21 ? 76 ARG F CD 1 +ATOM 10102 N NE . ARG F 1 76 ? 71.080 -27.526 76.030 1.00 141.15 ? 76 ARG F NE 1 +ATOM 10103 C CZ . ARG F 1 76 ? 72.383 -27.284 75.908 1.00 124.79 ? 76 ARG F CZ 1 +ATOM 10104 N NH1 . ARG F 1 76 ? 72.863 -26.042 75.943 1.00 106.63 ? 76 ARG F NH1 1 +ATOM 10105 N NH2 . ARG F 1 76 ? 73.210 -28.306 75.718 1.00 119.50 ? 76 ARG F NH2 1 +ATOM 10106 N N . TRP F 1 77 ? 70.773 -23.931 70.682 1.00 80.22 ? 77 TRP F N 1 +ATOM 10107 C CA . TRP F 1 77 ? 71.499 -22.960 69.874 1.00 119.87 ? 77 TRP F CA 1 +ATOM 10108 C C . TRP F 1 77 ? 70.568 -21.838 69.322 1.00 121.34 ? 77 TRP F C 1 +ATOM 10109 O O . TRP F 1 77 ? 70.994 -20.695 69.120 1.00 83.28 ? 77 TRP F O 1 +ATOM 10110 C CB . TRP F 1 77 ? 72.179 -23.703 68.722 1.00 120.16 ? 77 TRP F CB 1 +ATOM 10111 C CG . TRP F 1 77 ? 73.530 -24.158 69.032 1.00 118.10 ? 77 TRP F CG 1 +ATOM 10112 C CD1 . TRP F 1 77 ? 73.876 -25.198 69.825 1.00 139.09 ? 77 TRP F CD1 1 +ATOM 10113 C CD2 . TRP F 1 77 ? 74.749 -23.579 68.566 1.00 115.06 ? 77 TRP F CD2 1 +ATOM 10114 N NE1 . TRP F 1 77 ? 75.238 -25.308 69.885 1.00 163.70 ? 77 TRP F NE1 1 +ATOM 10115 C CE2 . TRP F 1 77 ? 75.797 -24.328 69.108 1.00 126.72 ? 77 TRP F CE2 1 +ATOM 10116 C CE3 . TRP F 1 77 ? 75.055 -22.509 67.729 1.00 141.99 ? 77 TRP F CE3 1 +ATOM 10117 C CZ2 . TRP F 1 77 ? 77.142 -24.058 68.826 1.00 133.11 ? 77 TRP F CZ2 1 +ATOM 10118 C CZ3 . TRP F 1 77 ? 76.393 -22.223 67.473 1.00 170.74 ? 77 TRP F CZ3 1 +ATOM 10119 C CH2 . TRP F 1 77 ? 77.417 -23.000 68.019 1.00 141.00 ? 77 TRP F CH2 1 +ATOM 10120 N N . PHE F 1 78 ? 69.317 -22.201 69.037 1.00 124.03 ? 78 PHE F N 1 +ATOM 10121 C CA . PHE F 1 78 ? 68.374 -21.340 68.332 1.00 92.18 ? 78 PHE F CA 1 +ATOM 10122 C C . PHE F 1 78 ? 67.119 -21.081 69.163 1.00 97.00 ? 78 PHE F C 1 +ATOM 10123 O O . PHE F 1 78 ? 66.598 -21.989 69.836 1.00 80.86 ? 78 PHE F O 1 +ATOM 10124 C CB . PHE F 1 78 ? 67.935 -22.008 67.031 1.00 102.45 ? 78 PHE F CB 1 +ATOM 10125 C CG . PHE F 1 78 ? 69.070 -22.384 66.113 1.00 99.44 ? 78 PHE F CG 1 +ATOM 10126 C CD1 . PHE F 1 78 ? 69.709 -21.415 65.329 1.00 84.10 ? 78 PHE F CD1 1 +ATOM 10127 C CD2 . PHE F 1 78 ? 69.409 -23.723 65.945 1.00 81.32 ? 78 PHE F CD2 1 +ATOM 10128 C CE1 . PHE F 1 78 ? 70.700 -21.767 64.443 1.00 75.03 ? 78 PHE F CE1 1 +ATOM 10129 C CE2 . PHE F 1 78 ? 70.392 -24.079 65.056 1.00 80.26 ? 78 PHE F CE2 1 +ATOM 10130 C CZ . PHE F 1 78 ? 71.060 -23.095 64.325 1.00 78.40 ? 78 PHE F CZ 1 +ATOM 10131 N N . ILE F 1 79 ? 66.598 -19.863 69.039 1.00 103.79 ? 79 ILE F N 1 +ATOM 10132 C CA . ILE F 1 79 ? 65.230 -19.517 69.451 1.00 106.95 ? 79 ILE F CA 1 +ATOM 10133 C C . ILE F 1 79 ? 64.352 -19.506 68.217 1.00 86.76 ? 79 ILE F C 1 +ATOM 10134 O O . ILE F 1 79 ? 64.728 -18.882 67.207 1.00 94.77 ? 79 ILE F O 1 +ATOM 10135 C CB . ILE F 1 79 ? 65.169 -18.100 70.030 1.00 126.10 ? 79 ILE F CB 1 +ATOM 10136 C CG1 . ILE F 1 79 ? 66.262 -17.883 71.076 1.00 146.02 ? 79 ILE F CG1 1 +ATOM 10137 C CG2 . ILE F 1 79 ? 63.803 -17.838 70.635 1.00 150.33 ? 79 ILE F CG2 1 +ATOM 10138 C CD1 . ILE F 1 79 ? 66.628 -16.422 71.287 1.00 116.82 ? 79 ILE F CD1 1 +ATOM 10139 N N . PRO F 1 80 ? 63.299 -20.326 68.228 1.00 87.57 ? 80 PRO F N 1 +ATOM 10140 C CA . PRO F 1 80 ? 62.552 -20.319 67.009 1.00 107.60 ? 80 PRO F CA 1 +ATOM 10141 C C . PRO F 1 80 ? 61.493 -19.291 67.148 1.00 78.78 ? 80 PRO F C 1 +ATOM 10142 O O . PRO F 1 80 ? 60.804 -19.254 68.153 1.00 79.11 ? 80 PRO F O 1 +ATOM 10143 C CB . PRO F 1 80 ? 61.972 -21.745 66.932 1.00 131.93 ? 80 PRO F CB 1 +ATOM 10144 C CG . PRO F 1 80 ? 62.926 -22.570 67.713 1.00 120.59 ? 80 PRO F CG 1 +ATOM 10145 C CD . PRO F 1 80 ? 63.258 -21.655 68.861 1.00 108.64 ? 80 PRO F CD 1 +ATOM 10146 N N . LEU F 1 81 ? 61.310 -18.533 66.094 1.00 59.07 ? 81 LEU F N 1 +ATOM 10147 C CA . LEU F 1 81 ? 60.208 -17.680 66.009 1.00 77.53 ? 81 LEU F CA 1 +ATOM 10148 C C . LEU F 1 81 ? 59.072 -18.399 65.280 1.00 91.00 ? 81 LEU F C 1 +ATOM 10149 O O . LEU F 1 81 ? 59.286 -19.086 64.271 1.00 65.96 ? 81 LEU F O 1 +ATOM 10150 C CB . LEU F 1 81 ? 60.635 -16.385 65.324 1.00 110.11 ? 81 LEU F CB 1 +ATOM 10151 C CG . LEU F 1 81 ? 61.848 -15.771 66.030 1.00 107.97 ? 81 LEU F CG 1 +ATOM 10152 C CD1 . LEU F 1 81 ? 62.317 -14.582 65.221 1.00 112.31 ? 81 LEU F CD1 1 +ATOM 10153 C CD2 . LEU F 1 81 ? 61.488 -15.359 67.441 1.00 91.32 ? 81 LEU F CD2 1 +ATOM 10154 N N . GLU F 1 82 ? 57.852 -18.160 65.784 1.00 113.90 ? 82 GLU F N 1 +ATOM 10155 C CA . GLU F 1 82 ? 56.641 -18.754 65.241 1.00 77.01 ? 82 GLU F CA 1 +ATOM 10156 C C . GLU F 1 82 ? 56.223 -18.052 63.932 1.00 97.37 ? 82 GLU F C 1 +ATOM 10157 O O . GLU F 1 82 ? 55.664 -16.923 63.930 1.00 110.12 ? 82 GLU F O 1 +ATOM 10158 C CB . GLU F 1 82 ? 55.508 -18.760 66.273 1.00 56.04 ? 82 GLU F CB 1 +ATOM 10159 C CG . GLU F 1 82 ? 54.220 -19.403 65.781 1.00 75.43 ? 82 GLU F CG 1 +ATOM 10160 C CD . GLU F 1 82 ? 54.288 -20.942 65.591 1.00 77.52 ? 82 GLU F CD 1 +ATOM 10161 O OE1 . GLU F 1 82 ? 55.198 -21.469 64.913 1.00 71.87 ? 82 GLU F OE1 1 +ATOM 10162 O OE2 . GLU F 1 82 ? 53.319 -21.626 65.989 1.00 72.47 ? 82 GLU F OE2 1 +ATOM 10163 N N . ARG F 1 83 ? 56.426 -18.775 62.824 1.00 88.78 ? 83 ARG F N 1 +ATOM 10164 C CA . ARG F 1 83 ? 55.883 -18.391 61.524 1.00 108.08 ? 83 ARG F CA 1 +ATOM 10165 C C . ARG F 1 83 ? 54.879 -19.421 60.901 1.00 124.62 ? 83 ARG F C 1 +ATOM 10166 O O . ARG F 1 83 ? 54.121 -19.066 59.996 1.00 81.13 ? 83 ARG F O 1 +ATOM 10167 C CB . ARG F 1 83 ? 57.051 -18.112 60.579 1.00 86.38 ? 83 ARG F CB 1 +ATOM 10168 C CG . ARG F 1 83 ? 58.027 -17.111 61.119 1.00 78.98 ? 83 ARG F CG 1 +ATOM 10169 C CD . ARG F 1 83 ? 57.440 -15.717 61.167 1.00 106.24 ? 83 ARG F CD 1 +ATOM 10170 N NE . ARG F 1 83 ? 58.529 -14.794 61.468 1.00 125.47 ? 83 ARG F NE 1 +ATOM 10171 C CZ . ARG F 1 83 ? 58.765 -14.223 62.651 1.00 115.61 ? 83 ARG F CZ 1 +ATOM 10172 N NH1 . ARG F 1 83 ? 57.912 -14.377 63.669 1.00 96.09 ? 83 ARG F NH1 1 +ATOM 10173 N NH2 . ARG F 1 83 ? 59.856 -13.455 62.789 1.00 99.19 ? 83 ARG F NH2 1 +ATOM 10174 N N . GLN F 1 84 ? 54.874 -20.677 61.364 1.00 134.74 ? 84 GLN F N 1 +ATOM 10175 C CA . GLN F 1 84 ? 53.968 -21.673 60.772 1.00 118.67 ? 84 GLN F CA 1 +ATOM 10176 C C . GLN F 1 84 ? 52.542 -21.253 60.988 1.00 87.34 ? 84 GLN F C 1 +ATOM 10177 O O . GLN F 1 84 ? 51.737 -21.269 60.068 1.00 145.27 ? 84 GLN F O 1 +ATOM 10178 C CB . GLN F 1 84 ? 54.177 -23.075 61.321 1.00 129.80 ? 84 GLN F CB 1 +ATOM 10179 C CG . GLN F 1 84 ? 53.825 -24.183 60.325 1.00 136.37 ? 84 GLN F CG 1 +ATOM 10180 C CD . GLN F 1 84 ? 53.892 -25.550 60.977 1.00 186.29 ? 84 GLN F CD 1 +ATOM 10181 O OE1 . GLN F 1 84 ? 54.832 -25.846 61.748 1.00 310.63 ? 84 GLN F OE1 1 +ATOM 10182 N NE2 . GLN F 1 84 ? 52.975 -26.434 60.602 1.00 165.65 ? 84 GLN F NE2 1 +ATOM 10183 N N . GLY F 1 85 ? 52.250 -20.694 62.139 1.00 77.34 ? 85 GLY F N 1 +ATOM 10184 C CA . GLY F 1 85 ? 50.905 -20.147 62.340 1.00 107.39 ? 85 GLY F CA 1 +ATOM 10185 C C . GLY F 1 85 ? 50.880 -18.630 62.433 1.00 106.68 ? 85 GLY F C 1 +ATOM 10186 O O . GLY F 1 85 ? 50.068 -18.076 63.195 1.00 141.07 ? 85 GLY F O 1 +ATOM 10187 N N . LEU F 1 86 ? 51.664 -17.952 61.586 1.00 80.65 ? 86 LEU F N 1 +ATOM 10188 C CA . LEU F 1 86 ? 51.817 -16.501 61.691 1.00 70.51 ? 86 LEU F CA 1 +ATOM 10189 C C . LEU F 1 86 ? 50.472 -15.733 61.613 1.00 84.88 ? 86 LEU F C 1 +ATOM 10190 O O . LEU F 1 86 ? 50.275 -14.713 62.290 1.00 74.30 ? 86 LEU F O 1 +ATOM 10191 C CB . LEU F 1 86 ? 52.739 -15.969 60.600 1.00 77.82 ? 86 LEU F CB 1 +ATOM 10192 C CG . LEU F 1 86 ? 52.954 -14.445 60.433 1.00 99.33 ? 86 LEU F CG 1 +ATOM 10193 C CD1 . LEU F 1 86 ? 53.519 -13.796 61.688 1.00 99.82 ? 86 LEU F CD1 1 +ATOM 10194 C CD2 . LEU F 1 86 ? 53.876 -14.165 59.251 1.00 109.46 ? 86 LEU F CD2 1 +ATOM 10195 N N . GLN F 1 87 ? 49.541 -16.219 60.795 1.00 85.80 ? 87 GLN F N 1 +ATOM 10196 C CA . GLN F 1 87 ? 48.288 -15.498 60.568 1.00 91.19 ? 87 GLN F CA 1 +ATOM 10197 C C . GLN F 1 87 ? 47.461 -15.322 61.872 1.00 62.94 ? 87 GLN F C 1 +ATOM 10198 O O . GLN F 1 87 ? 46.936 -14.257 62.181 1.00 71.15 ? 87 GLN F O 1 +ATOM 10199 C CB . GLN F 1 87 ? 47.484 -16.211 59.463 1.00 123.89 ? 87 GLN F CB 1 +ATOM 10200 C CG . GLN F 1 87 ? 46.677 -15.265 58.578 1.00 147.01 ? 87 GLN F CG 1 +ATOM 10201 C CD . GLN F 1 87 ? 47.442 -14.004 58.175 1.00 150.34 ? 87 GLN F CD 1 +ATOM 10202 O OE1 . GLN F 1 87 ? 48.517 -14.072 57.578 1.00 125.59 ? 87 GLN F OE1 1 +ATOM 10203 N NE2 . GLN F 1 87 ? 46.878 -12.838 58.503 1.00 172.88 ? 87 GLN F NE2 1 +ATOM 10204 N N . ASN F 1 88 ? 47.343 -16.393 62.614 1.00 60.69 ? 88 ASN F N 1 +ATOM 10205 C CA . ASN F 1 88 ? 46.664 -16.367 63.882 1.00 76.43 ? 88 ASN F CA 1 +ATOM 10206 C C . ASN F 1 88 ? 47.344 -15.405 64.850 1.00 84.17 ? 88 ASN F C 1 +ATOM 10207 O O . ASN F 1 88 ? 46.698 -14.824 65.737 1.00 87.04 ? 88 ASN F O 1 +ATOM 10208 C CB . ASN F 1 88 ? 46.680 -17.779 64.508 1.00 114.80 ? 88 ASN F CB 1 +ATOM 10209 C CG . ASN F 1 88 ? 46.036 -18.803 63.620 1.00 94.81 ? 88 ASN F CG 1 +ATOM 10210 O OD1 . ASN F 1 88 ? 45.071 -18.474 62.932 1.00 46.42 ? 88 ASN F OD1 1 +ATOM 10211 N ND2 . ASN F 1 88 ? 46.632 -20.016 63.548 1.00 88.42 ? 88 ASN F ND2 1 +ATOM 10212 N N . LEU F 1 89 ? 48.673 -15.389 64.806 1.00 89.33 ? 89 LEU F N 1 +ATOM 10213 C CA . LEU F 1 89 ? 49.460 -14.603 65.733 1.00 90.84 ? 89 LEU F CA 1 +ATOM 10214 C C . LEU F 1 89 ? 49.070 -13.124 65.490 1.00 109.90 ? 89 LEU F C 1 +ATOM 10215 O O . LEU F 1 89 ? 48.850 -12.350 66.435 1.00 105.34 ? 89 LEU F O 1 +ATOM 10216 C CB . LEU F 1 89 ? 50.963 -14.886 65.493 1.00 64.18 ? 89 LEU F CB 1 +ATOM 10217 C CG . LEU F 1 89 ? 51.967 -14.732 66.621 1.00 53.05 ? 89 LEU F CG 1 +ATOM 10218 C CD1 . LEU F 1 89 ? 52.908 -13.591 66.341 1.00 58.53 ? 89 LEU F CD1 1 +ATOM 10219 C CD2 . LEU F 1 89 ? 51.274 -14.463 67.955 1.00 56.31 ? 89 LEU F CD2 1 +ATOM 10220 N N . LEU F 1 90 ? 48.957 -12.769 64.217 1.00 108.44 ? 90 LEU F N 1 +ATOM 10221 C CA . LEU F 1 90 ? 48.669 -11.392 63.835 1.00 104.87 ? 90 LEU F CA 1 +ATOM 10222 C C . LEU F 1 90 ? 47.239 -11.041 64.206 1.00 109.75 ? 90 LEU F C 1 +ATOM 10223 O O . LEU F 1 90 ? 46.912 -9.887 64.516 1.00 150.75 ? 90 LEU F O 1 +ATOM 10224 C CB . LEU F 1 90 ? 48.885 -11.205 62.340 1.00 85.38 ? 90 LEU F CB 1 +ATOM 10225 C CG . LEU F 1 90 ? 50.307 -11.467 61.902 1.00 93.48 ? 90 LEU F CG 1 +ATOM 10226 C CD1 . LEU F 1 90 ? 50.333 -11.712 60.400 1.00 101.45 ? 90 LEU F CD1 1 +ATOM 10227 C CD2 . LEU F 1 90 ? 51.192 -10.294 62.299 1.00 118.26 ? 90 LEU F CD2 1 +ATOM 10228 N N . ASN F 1 91 ? 46.386 -12.052 64.189 1.00 98.15 ? 91 ASN F N 1 +ATOM 10229 C CA . ASN F 1 91 ? 45.010 -11.860 64.559 1.00 97.41 ? 91 ASN F CA 1 +ATOM 10230 C C . ASN F 1 91 ? 44.860 -11.575 66.036 1.00 115.28 ? 91 ASN F C 1 +ATOM 10231 O O . ASN F 1 91 ? 44.124 -10.660 66.422 1.00 132.20 ? 91 ASN F O 1 +ATOM 10232 C CB . ASN F 1 91 ? 44.168 -13.059 64.158 1.00 102.14 ? 91 ASN F CB 1 +ATOM 10233 C CG . ASN F 1 91 ? 42.959 -12.611 63.381 1.00 82.21 ? 91 ASN F CG 1 +ATOM 10234 O OD1 . ASN F 1 91 ? 43.128 -11.949 62.357 1.00 68.09 ? 91 ASN F OD1 1 +ATOM 10235 N ND2 . ASN F 1 91 ? 41.747 -12.839 63.910 1.00 85.99 ? 91 ASN F ND2 1 +ATOM 10236 N N . GLU F 1 92 ? 45.499 -12.398 66.860 1.00 104.09 ? 92 GLU F N 1 +ATOM 10237 C CA . GLU F 1 92 ? 45.417 -12.192 68.293 1.00 115.01 ? 92 GLU F CA 1 +ATOM 10238 C C . GLU F 1 92 ? 45.927 -10.797 68.619 1.00 102.17 ? 92 GLU F C 1 +ATOM 10239 O O . GLU F 1 92 ? 45.447 -10.137 69.564 1.00 107.40 ? 92 GLU F O 1 +ATOM 10240 C CB . GLU F 1 92 ? 46.214 -13.257 69.055 1.00 117.36 ? 92 GLU F CB 1 +ATOM 10241 C CG . GLU F 1 92 ? 45.392 -14.457 69.492 1.00 91.75 ? 92 GLU F CG 1 +ATOM 10242 C CD . GLU F 1 92 ? 44.125 -14.072 70.267 1.00 85.37 ? 92 GLU F CD 1 +ATOM 10243 O OE1 . GLU F 1 92 ? 44.208 -13.415 71.363 1.00 64.34 ? 92 GLU F OE1 1 +ATOM 10244 O OE2 . GLU F 1 92 ? 43.043 -14.521 69.822 1.00 75.64 ? 92 GLU F OE2 1 +ATOM 10245 N N . ARG F 1 93 ? 46.963 -10.379 67.902 1.00 74.77 ? 93 ARG F N 1 +ATOM 10246 C CA . ARG F 1 93 ? 47.516 -9.054 68.128 1.00 98.09 ? 93 ARG F CA 1 +ATOM 10247 C C . ARG F 1 93 ? 46.519 -7.947 67.694 1.00 125.42 ? 93 ARG F C 1 +ATOM 10248 O O . ARG F 1 93 ? 46.436 -6.892 68.323 1.00 142.66 ? 93 ARG F O 1 +ATOM 10249 C CB . ARG F 1 93 ? 48.871 -8.946 67.444 1.00 86.95 ? 93 ARG F CB 1 +ATOM 10250 C CG . ARG F 1 93 ? 49.908 -9.815 68.119 1.00 72.72 ? 93 ARG F CG 1 +ATOM 10251 C CD . ARG F 1 93 ? 51.160 -10.029 67.280 1.00 86.81 ? 93 ARG F CD 1 +ATOM 10252 N NE . ARG F 1 93 ? 52.268 -9.187 67.712 1.00 91.19 ? 93 ARG F NE 1 +ATOM 10253 C CZ . ARG F 1 93 ? 52.620 -8.038 67.145 1.00 101.85 ? 93 ARG F CZ 1 +ATOM 10254 N NH1 . ARG F 1 93 ? 51.945 -7.539 66.117 1.00 121.26 ? 93 ARG F NH1 1 +ATOM 10255 N NH2 . ARG F 1 93 ? 53.677 -7.393 67.607 1.00 117.37 ? 93 ARG F NH2 1 +ATOM 10256 N N . LYS F 1 94 ? 45.711 -8.210 66.668 1.00 115.73 ? 94 LYS F N 1 +ATOM 10257 C CA . LYS F 1 94 ? 44.650 -7.273 66.292 1.00 90.39 ? 94 LYS F CA 1 +ATOM 10258 C C . LYS F 1 94 ? 43.651 -7.180 67.425 1.00 82.27 ? 94 LYS F C 1 +ATOM 10259 O O . LYS F 1 94 ? 43.145 -6.068 67.728 1.00 77.86 ? 94 LYS F O 1 +ATOM 10260 C CB . LYS F 1 94 ? 43.919 -7.736 65.044 1.00 113.03 ? 94 LYS F CB 1 +ATOM 10261 C CG . LYS F 1 94 ? 44.507 -7.268 63.721 1.00 131.56 ? 94 LYS F CG 1 +ATOM 10262 C CD . LYS F 1 94 ? 43.795 -7.969 62.565 1.00 135.73 ? 94 LYS F CD 1 +ATOM 10263 C CE . LYS F 1 94 ? 43.948 -7.243 61.241 1.00 120.07 ? 94 LYS F CE 1 +ATOM 10264 N NZ . LYS F 1 94 ? 43.540 -8.138 60.123 1.00 132.70 ? 94 LYS F NZ 1 +ATOM 10265 N N . ILE F 1 95 ? 43.365 -8.331 68.059 1.00 60.78 ? 95 ILE F N 1 +ATOM 10266 C CA . ILE F 1 95 ? 42.308 -8.370 69.073 1.00 69.58 ? 95 ILE F CA 1 +ATOM 10267 C C . ILE F 1 95 ? 42.748 -7.652 70.345 1.00 73.32 ? 95 ILE F C 1 +ATOM 10268 O O . ILE F 1 95 ? 41.949 -6.910 70.996 1.00 34.25 ? 95 ILE F O 1 +ATOM 10269 C CB . ILE F 1 95 ? 41.867 -9.779 69.447 1.00 51.74 ? 95 ILE F CB 1 +ATOM 10270 C CG1 . ILE F 1 95 ? 41.550 -10.575 68.221 1.00 60.89 ? 95 ILE F CG1 1 +ATOM 10271 C CG2 . ILE F 1 95 ? 40.583 -9.647 70.267 1.00 69.37 ? 95 ILE F CG2 1 +ATOM 10272 C CD1 . ILE F 1 95 ? 40.778 -11.844 68.471 1.00 88.13 ? 95 ILE F CD1 1 +ATOM 10273 N N . ILE F 1 96 ? 44.032 -7.860 70.657 1.00 82.84 ? 96 ILE F N 1 +ATOM 10274 C CA . ILE F 1 96 ? 44.705 -7.130 71.738 1.00 79.34 ? 96 ILE F CA 1 +ATOM 10275 C C . ILE F 1 96 ? 44.598 -5.645 71.503 1.00 82.32 ? 96 ILE F C 1 +ATOM 10276 O O . ILE F 1 96 ? 44.038 -4.926 72.320 1.00 86.70 ? 96 ILE F O 1 +ATOM 10277 C CB . ILE F 1 96 ? 46.191 -7.506 71.871 1.00 62.35 ? 96 ILE F CB 1 +ATOM 10278 C CG1 . ILE F 1 96 ? 46.296 -8.951 72.330 1.00 83.38 ? 96 ILE F CG1 1 +ATOM 10279 C CG2 . ILE F 1 96 ? 46.850 -6.633 72.898 1.00 47.20 ? 96 ILE F CG2 1 +ATOM 10280 C CD1 . ILE F 1 96 ? 47.721 -9.395 72.552 1.00 113.08 ? 96 ILE F CD1 1 +ATOM 10281 N N . ARG F 1 97 ? 45.113 -5.190 70.362 1.00 80.08 ? 97 ARG F N 1 +ATOM 10282 C CA . ARG F 1 97 ? 45.149 -3.752 70.062 1.00 79.79 ? 97 ARG F CA 1 +ATOM 10283 C C . ARG F 1 97 ? 43.742 -3.131 70.046 1.00 70.09 ? 97 ARG F C 1 +ATOM 10284 O O . ARG F 1 97 ? 43.566 -1.960 70.399 1.00 48.28 ? 97 ARG F O 1 +ATOM 10285 C CB . ARG F 1 97 ? 45.855 -3.478 68.730 1.00 86.40 ? 97 ARG F CB 1 +ATOM 10286 C CG . ARG F 1 97 ? 47.283 -2.970 68.860 1.00 96.85 ? 97 ARG F CG 1 +ATOM 10287 C CD . ARG F 1 97 ? 47.873 -2.655 67.496 1.00 99.06 ? 97 ARG F CD 1 +ATOM 10288 N NE . ARG F 1 97 ? 48.357 -3.858 66.820 1.00 93.62 ? 97 ARG F NE 1 +ATOM 10289 C CZ . ARG F 1 97 ? 49.635 -4.252 66.804 1.00 97.41 ? 97 ARG F CZ 1 +ATOM 10290 N NH1 . ARG F 1 97 ? 50.603 -3.544 67.408 1.00 64.89 ? 97 ARG F NH1 1 +ATOM 10291 N NH2 . ARG F 1 97 ? 49.955 -5.371 66.168 1.00 117.15 ? 97 ARG F NH2 1 +ATOM 10292 N N . ALA F 1 98 ? 42.753 -3.927 69.654 1.00 57.21 ? 98 ALA F N 1 +ATOM 10293 C CA . ALA F 1 98 ? 41.393 -3.456 69.643 1.00 68.05 ? 98 ALA F CA 1 +ATOM 10294 C C . ALA F 1 98 ? 40.839 -3.359 71.072 1.00 82.12 ? 98 ALA F C 1 +ATOM 10295 O O . ALA F 1 98 ? 39.945 -2.539 71.366 1.00 57.06 ? 98 ALA F O 1 +ATOM 10296 C CB . ALA F 1 98 ? 40.541 -4.369 68.777 1.00 58.93 ? 98 ALA F CB 1 +ATOM 10297 N N . ALA F 1 99 ? 41.355 -4.229 71.940 1.00 98.26 ? 99 ALA F N 1 +ATOM 10298 C CA . ALA F 1 99 ? 40.919 -4.277 73.329 1.00 93.80 ? 99 ALA F CA 1 +ATOM 10299 C C . ALA F 1 99 ? 41.325 -2.997 74.072 1.00 76.35 ? 99 ALA F C 1 +ATOM 10300 O O . ALA F 1 99 ? 40.541 -2.404 74.796 1.00 40.80 ? 99 ALA F O 1 +ATOM 10301 C CB . ALA F 1 99 ? 41.478 -5.537 74.017 1.00 78.33 ? 99 ALA F CB 1 +ATOM 10302 N N . GLN F 1 100 ? 42.605 -2.665 73.972 1.00 103.41 ? 100 GLN F N 1 +ATOM 10303 C CA . GLN F 1 100 ? 43.240 -1.759 74.938 1.00 125.28 ? 100 GLN F CA 1 +ATOM 10304 C C . GLN F 1 100 ? 43.520 -0.394 74.359 1.00 116.44 ? 100 GLN F C 1 +ATOM 10305 O O . GLN F 1 100 ? 44.154 0.437 75.013 1.00 127.03 ? 100 GLN F O 1 +ATOM 10306 C CB . GLN F 1 100 ? 44.534 -2.374 75.531 1.00 127.26 ? 100 GLN F CB 1 +ATOM 10307 C CG . GLN F 1 100 ? 45.436 -3.092 74.539 1.00 113.10 ? 100 GLN F CG 1 +ATOM 10308 C CD . GLN F 1 100 ? 46.281 -4.206 75.154 1.00 126.12 ? 100 GLN F CD 1 +ATOM 10309 O OE1 . GLN F 1 100 ? 45.771 -5.173 75.755 1.00 123.34 ? 100 GLN F OE1 1 +ATOM 10310 N NE2 . GLN F 1 100 ? 47.592 -4.065 75.015 1.00 142.86 ? 100 GLN F NE2 1 +ATOM 10311 N N . GLU F 1 101 ? 43.048 -0.158 73.139 1.00 106.30 ? 101 GLU F N 1 +ATOM 10312 C CA . GLU F 1 101 ? 43.291 1.128 72.468 1.00 121.00 ? 101 GLU F CA 1 +ATOM 10313 C C . GLU F 1 101 ? 42.573 2.309 73.151 1.00 117.03 ? 101 GLU F C 1 +ATOM 10314 O O . GLU F 1 101 ? 43.006 3.453 73.027 1.00 102.83 ? 101 GLU F O 1 +ATOM 10315 C CB . GLU F 1 101 ? 42.905 1.054 70.990 1.00 106.12 ? 101 GLU F CB 1 +ATOM 10316 C CG . GLU F 1 101 ? 41.497 0.544 70.733 1.00 138.05 ? 101 GLU F CG 1 +ATOM 10317 C CD . GLU F 1 101 ? 41.124 0.565 69.253 1.00 120.86 ? 101 GLU F CD 1 +ATOM 10318 O OE1 . GLU F 1 101 ? 42.052 0.661 68.424 1.00 91.02 ? 101 GLU F OE1 1 +ATOM 10319 O OE2 . GLU F 1 101 ? 39.901 0.501 68.938 1.00 84.47 ? 101 GLU F OE2 1 +ATOM 10320 N N . ASN F 1 102 ? 41.505 2.024 73.893 1.00 94.44 ? 102 ASN F N 1 +ATOM 10321 C CA . ASN F 1 102 ? 40.741 3.076 74.529 1.00 83.60 ? 102 ASN F CA 1 +ATOM 10322 C C . ASN F 1 102 ? 41.207 3.365 75.959 1.00 112.48 ? 102 ASN F C 1 +ATOM 10323 O O . ASN F 1 102 ? 40.670 4.261 76.619 1.00 122.69 ? 102 ASN F O 1 +ATOM 10324 C CB . ASN F 1 102 ? 39.257 2.709 74.552 1.00 75.80 ? 102 ASN F CB 1 +ATOM 10325 C CG . ASN F 1 102 ? 38.613 2.801 73.208 1.00 71.56 ? 102 ASN F CG 1 +ATOM 10326 O OD1 . ASN F 1 102 ? 38.390 3.905 72.672 1.00 81.76 ? 102 ASN F OD1 1 +ATOM 10327 N ND2 . ASN F 1 102 ? 38.422 1.641 72.586 1.00 75.57 ? 102 ASN F ND2 1 +ATOM 10328 N N . GLY F 1 103 ? 42.169 2.594 76.466 1.00 125.28 ? 103 GLY F N 1 +ATOM 10329 C CA . GLY F 1 103 ? 42.665 2.797 77.836 1.00 113.74 ? 103 GLY F CA 1 +ATOM 10330 C C . GLY F 1 103 ? 41.614 2.620 78.918 1.00 93.99 ? 103 GLY F C 1 +ATOM 10331 O O . GLY F 1 103 ? 41.622 3.318 79.937 1.00 115.91 ? 103 GLY F O 1 +ATOM 10332 N N . THR F 1 104 ? 40.680 1.720 78.679 1.00 71.89 ? 104 THR F N 1 +ATOM 10333 C CA . THR F 1 104 ? 39.775 1.321 79.713 1.00 76.94 ? 104 THR F CA 1 +ATOM 10334 C C . THR F 1 104 ? 40.232 -0.002 80.271 1.00 94.29 ? 104 THR F C 1 +ATOM 10335 O O . THR F 1 104 ? 39.973 -0.284 81.442 1.00 147.36 ? 104 THR F O 1 +ATOM 10336 C CB . THR F 1 104 ? 38.322 1.198 79.221 1.00 91.71 ? 104 THR F CB 1 +ATOM 10337 O OG1 . THR F 1 104 ? 38.193 0.159 78.229 1.00 108.46 ? 104 THR F OG1 1 +ATOM 10338 C CG2 . THR F 1 104 ? 37.857 2.523 78.637 1.00 105.42 ? 104 THR F CG2 1 +ATOM 10339 N N . VAL F 1 105 ? 40.932 -0.811 79.474 1.00 105.01 ? 105 VAL F N 1 +ATOM 10340 C CA . VAL F 1 105 ? 41.267 -2.176 79.911 1.00 134.75 ? 105 VAL F CA 1 +ATOM 10341 C C . VAL F 1 105 ? 42.089 -2.172 81.205 1.00 139.01 ? 105 VAL F C 1 +ATOM 10342 O O . VAL F 1 105 ? 42.955 -1.313 81.411 1.00 147.77 ? 105 VAL F O 1 +ATOM 10343 C CB . VAL F 1 105 ? 41.974 -3.019 78.814 1.00 159.17 ? 105 VAL F CB 1 +ATOM 10344 C CG1 . VAL F 1 105 ? 42.979 -4.011 79.411 1.00 152.91 ? 105 VAL F CG1 1 +ATOM 10345 C CG2 . VAL F 1 105 ? 40.948 -3.779 77.964 1.00 174.22 ? 105 VAL F CG2 1 +ATOM 10346 N N . ALA F 1 106 ? 41.751 -3.114 82.089 1.00 139.60 ? 106 ALA F N 1 +ATOM 10347 C CA . ALA F 1 106 ? 42.273 -3.167 83.447 1.00 128.67 ? 106 ALA F CA 1 +ATOM 10348 C C . ALA F 1 106 ? 43.784 -3.345 83.430 1.00 129.59 ? 106 ALA F C 1 +ATOM 10349 O O . ALA F 1 106 ? 44.310 -4.197 82.707 1.00 168.53 ? 106 ALA F O 1 +ATOM 10350 C CB . ALA F 1 106 ? 41.604 -4.302 84.220 1.00 123.25 ? 106 ALA F CB 1 +ATOM 10351 N N . ILE F 1 107 ? 44.472 -2.550 84.245 1.00 127.96 ? 107 ILE F N 1 +ATOM 10352 C CA . ILE F 1 107 ? 45.938 -2.518 84.261 1.00 136.07 ? 107 ILE F CA 1 +ATOM 10353 C C . ILE F 1 107 ? 46.590 -3.896 84.555 1.00 132.56 ? 107 ILE F C 1 +ATOM 10354 O O . ILE F 1 107 ? 47.674 -4.207 84.062 1.00 97.66 ? 107 ILE F O 1 +ATOM 10355 C CB . ILE F 1 107 ? 46.441 -1.457 85.269 1.00 133.25 ? 107 ILE F CB 1 +ATOM 10356 C CG1 . ILE F 1 107 ? 47.933 -1.177 85.071 1.00 133.36 ? 107 ILE F CG1 1 +ATOM 10357 C CG2 . ILE F 1 107 ? 46.167 -1.897 86.706 1.00 145.66 ? 107 ILE F CG2 1 +ATOM 10358 C CD1 . ILE F 1 107 ? 48.310 -0.714 83.677 1.00 112.28 ? 107 ILE F CD1 1 +ATOM 10359 N N . ASN F 1 108 ? 45.906 -4.723 85.338 1.00 152.30 ? 108 ASN F N 1 +ATOM 10360 C CA . ASN F 1 108 ? 46.342 -6.098 85.606 1.00 147.71 ? 108 ASN F CA 1 +ATOM 10361 C C . ASN F 1 108 ? 46.194 -6.972 84.366 1.00 142.44 ? 108 ASN F C 1 +ATOM 10362 O O . ASN F 1 108 ? 46.986 -7.882 84.127 1.00 150.16 ? 108 ASN F O 1 +ATOM 10363 C CB . ASN F 1 108 ? 45.508 -6.721 86.738 1.00 173.91 ? 108 ASN F CB 1 +ATOM 10364 C CG . ASN F 1 108 ? 45.026 -5.700 87.753 1.00 198.57 ? 108 ASN F CG 1 +ATOM 10365 O OD1 . ASN F 1 108 ? 45.743 -5.356 88.692 1.00 233.78 ? 108 ASN F OD1 1 +ATOM 10366 N ND2 . ASN F 1 108 ? 43.813 -5.191 87.555 1.00 209.91 ? 108 ASN F ND2 1 +ATOM 10367 N N . ASN F 1 109 ? 45.137 -6.715 83.606 1.00 139.69 ? 109 ASN F N 1 +ATOM 10368 C CA . ASN F 1 109 ? 44.782 -7.529 82.450 1.00 144.30 ? 109 ASN F CA 1 +ATOM 10369 C C . ASN F 1 109 ? 45.512 -7.112 81.166 1.00 138.11 ? 109 ASN F C 1 +ATOM 10370 O O . ASN F 1 109 ? 45.563 -7.875 80.194 1.00 124.71 ? 109 ASN F O 1 +ATOM 10371 C CB . ASN F 1 109 ? 43.269 -7.461 82.223 1.00 163.30 ? 109 ASN F CB 1 +ATOM 10372 C CG . ASN F 1 109 ? 42.592 -8.804 82.408 1.00 169.68 ? 109 ASN F CG 1 +ATOM 10373 O OD1 . ASN F 1 109 ? 42.071 -9.381 81.455 1.00 144.48 ? 109 ASN F OD1 1 +ATOM 10374 N ND2 . ASN F 1 109 ? 42.639 -9.330 83.625 1.00 172.68 ? 109 ASN F ND2 1 +ATOM 10375 N N . ARG F 1 110 ? 46.077 -5.905 81.184 1.00 127.62 ? 110 ARG F N 1 +ATOM 10376 C CA . ARG F 1 110 ? 46.703 -5.285 80.005 1.00 104.97 ? 110 ARG F CA 1 +ATOM 10377 C C . ARG F 1 110 ? 47.801 -6.175 79.415 1.00 107.90 ? 110 ARG F C 1 +ATOM 10378 O O . ARG F 1 110 ? 48.635 -6.709 80.152 1.00 120.02 ? 110 ARG F O 1 +ATOM 10379 C CB . ARG F 1 110 ? 47.308 -3.926 80.407 1.00 90.29 ? 110 ARG F CB 1 +ATOM 10380 C CG . ARG F 1 110 ? 47.478 -2.939 79.273 1.00 82.71 ? 110 ARG F CG 1 +ATOM 10381 C CD . ARG F 1 110 ? 47.263 -1.510 79.728 1.00 86.73 ? 110 ARG F CD 1 +ATOM 10382 N NE . ARG F 1 110 ? 48.512 -0.903 80.203 1.00 104.68 ? 110 ARG F NE 1 +ATOM 10383 C CZ . ARG F 1 110 ? 49.100 0.173 79.658 1.00 112.99 ? 110 ARG F CZ 1 +ATOM 10384 N NH1 . ARG F 1 110 ? 48.554 0.822 78.613 1.00 83.07 ? 110 ARG F NH1 1 +ATOM 10385 N NH2 . ARG F 1 110 ? 50.254 0.616 80.168 1.00 108.45 ? 110 ARG F NH2 1 +ATOM 10386 N N . ILE F 1 111 ? 47.808 -6.341 78.092 1.00 91.10 ? 111 ILE F N 1 +ATOM 10387 C CA . ILE F 1 111 ? 48.901 -7.055 77.428 1.00 80.78 ? 111 ILE F CA 1 +ATOM 10388 C C . ILE F 1 111 ? 49.782 -6.104 76.665 1.00 77.83 ? 111 ILE F C 1 +ATOM 10389 O O . ILE F 1 111 ? 49.319 -5.484 75.720 1.00 90.31 ? 111 ILE F O 1 +ATOM 10390 C CB . ILE F 1 111 ? 48.383 -8.105 76.456 1.00 86.07 ? 111 ILE F CB 1 +ATOM 10391 C CG1 . ILE F 1 111 ? 47.601 -9.173 77.233 1.00 127.21 ? 111 ILE F CG1 1 +ATOM 10392 C CG2 . ILE F 1 111 ? 49.544 -8.748 75.710 1.00 77.58 ? 111 ILE F CG2 1 +ATOM 10393 C CD1 . ILE F 1 111 ? 46.792 -10.122 76.365 1.00 156.97 ? 111 ILE F CD1 1 +ATOM 10394 N N . PRO F 1 112 ? 51.061 -5.976 77.068 1.00 87.13 ? 112 PRO F N 1 +ATOM 10395 C CA . PRO F 1 112 ? 51.965 -5.055 76.392 1.00 88.71 ? 112 PRO F CA 1 +ATOM 10396 C C . PRO F 1 112 ? 52.491 -5.655 75.079 1.00 104.22 ? 112 PRO F C 1 +ATOM 10397 O O . PRO F 1 112 ? 52.960 -6.803 75.051 1.00 70.90 ? 112 PRO F O 1 +ATOM 10398 C CB . PRO F 1 112 ? 53.100 -4.886 77.394 1.00 87.12 ? 112 PRO F CB 1 +ATOM 10399 C CG . PRO F 1 112 ? 53.174 -6.208 78.083 1.00 103.44 ? 112 PRO F CG 1 +ATOM 10400 C CD . PRO F 1 112 ? 51.781 -6.806 78.049 1.00 108.09 ? 112 PRO F CD 1 +ATOM 10401 N N . LEU F 1 113 ? 52.372 -4.881 74.003 1.00 109.50 ? 113 LEU F N 1 +ATOM 10402 C CA . LEU F 1 113 ? 52.677 -5.371 72.673 1.00 86.91 ? 113 LEU F CA 1 +ATOM 10403 C C . LEU F 1 113 ? 53.975 -4.801 72.160 1.00 94.46 ? 113 LEU F C 1 +ATOM 10404 O O . LEU F 1 113 ? 54.291 -3.621 72.329 1.00 128.62 ? 113 LEU F O 1 +ATOM 10405 C CB . LEU F 1 113 ? 51.531 -5.065 71.707 1.00 88.30 ? 113 LEU F CB 1 +ATOM 10406 C CG . LEU F 1 113 ? 50.407 -6.111 71.657 1.00 80.45 ? 113 LEU F CG 1 +ATOM 10407 C CD1 . LEU F 1 113 ? 49.431 -5.712 70.592 1.00 67.84 ? 113 LEU F CD1 1 +ATOM 10408 C CD2 . LEU F 1 113 ? 50.958 -7.505 71.372 1.00 96.90 ? 113 LEU F CD2 1 +ATOM 10409 N N . GLN F 1 114 ? 54.717 -5.665 71.502 1.00 96.26 ? 114 GLN F N 1 +ATOM 10410 C CA . GLN F 1 114 ? 56.093 -5.399 71.146 1.00 113.84 ? 114 GLN F CA 1 +ATOM 10411 C C . GLN F 1 114 ? 56.181 -5.874 69.726 1.00 119.93 ? 114 GLN F C 1 +ATOM 10412 O O . GLN F 1 114 ? 55.484 -6.829 69.350 1.00 174.08 ? 114 GLN F O 1 +ATOM 10413 C CB . GLN F 1 114 ? 57.025 -6.202 72.048 1.00 107.43 ? 114 GLN F CB 1 +ATOM 10414 C CG . GLN F 1 114 ? 58.403 -5.604 72.266 1.00 135.28 ? 114 GLN F CG 1 +ATOM 10415 C CD . GLN F 1 114 ? 59.435 -6.685 72.637 1.00 138.58 ? 114 GLN F CD 1 +ATOM 10416 O OE1 . GLN F 1 114 ? 59.065 -7.712 73.194 1.00 95.10 ? 114 GLN F OE1 1 +ATOM 10417 N NE2 . GLN F 1 114 ? 60.711 -6.466 72.290 1.00 113.54 ? 114 GLN F NE2 1 +ATOM 10418 N N . SER F 1 115 ? 57.002 -5.212 68.928 1.00 94.14 ? 115 SER F N 1 +ATOM 10419 C CA . SER F 1 115 ? 57.089 -5.561 67.507 1.00 105.02 ? 115 SER F CA 1 +ATOM 10420 C C . SER F 1 115 ? 57.515 -7.010 67.326 1.00 76.43 ? 115 SER F C 1 +ATOM 10421 O O . SER F 1 115 ? 58.105 -7.598 68.269 1.00 104.78 ? 115 SER F O 1 +ATOM 10422 C CB . SER F 1 115 ? 58.107 -4.658 66.835 1.00 122.62 ? 115 SER F CB 1 +ATOM 10423 O OG . SER F 1 115 ? 59.329 -4.631 67.567 1.00 67.08 ? 115 SER F OG 1 +ATOM 10424 N N . LEU F 1 116 ? 57.200 -7.622 66.182 1.00 46.37 ? 116 LEU F N 1 +ATOM 10425 C CA . LEU F 1 116 ? 57.372 -9.063 66.144 1.00 57.54 ? 116 LEU F CA 1 +ATOM 10426 C C . LEU F 1 116 ? 58.838 -9.338 66.017 1.00 59.03 ? 116 LEU F C 1 +ATOM 10427 O O . LEU F 1 116 ? 59.486 -8.742 65.174 1.00 58.82 ? 116 LEU F O 1 +ATOM 10428 C CB . LEU F 1 116 ? 56.641 -9.712 64.990 1.00 71.82 ? 116 LEU F CB 1 +ATOM 10429 C CG . LEU F 1 116 ? 55.112 -9.661 65.041 1.00 88.58 ? 116 LEU F CG 1 +ATOM 10430 C CD1 . LEU F 1 116 ? 54.572 -8.473 64.262 1.00 78.56 ? 116 LEU F CD1 1 +ATOM 10431 C CD2 . LEU F 1 116 ? 54.588 -10.983 64.487 1.00 106.50 ? 116 LEU F CD2 1 +ATOM 10432 N N . THR F 1 117 ? 59.386 -10.130 66.941 1.00 75.34 ? 117 THR F N 1 +ATOM 10433 C CA . THR F 1 117 ? 60.812 -10.402 66.976 1.00 98.70 ? 117 THR F CA 1 +ATOM 10434 C C . THR F 1 117 ? 61.153 -11.013 65.631 1.00 115.09 ? 117 THR F C 1 +ATOM 10435 O O . THR F 1 117 ? 60.454 -11.911 65.173 1.00 81.66 ? 117 THR F O 1 +ATOM 10436 C CB . THR F 1 117 ? 61.183 -11.403 68.094 1.00 125.74 ? 117 THR F CB 1 +ATOM 10437 O OG1 . THR F 1 117 ? 60.759 -10.889 69.360 1.00 90.84 ? 117 THR F OG1 1 +ATOM 10438 C CG2 . THR F 1 117 ? 62.692 -11.607 68.151 1.00 162.23 ? 117 THR F CG2 1 +ATOM 10439 N N . ALA F 1 118 ? 62.255 -10.553 65.034 1.00 129.45 ? 118 ALA F N 1 +ATOM 10440 C CA . ALA F 1 118 ? 62.580 -10.886 63.646 1.00 106.64 ? 118 ALA F CA 1 +ATOM 10441 C C . ALA F 1 118 ? 63.847 -11.669 63.552 1.00 80.59 ? 118 ALA F C 1 +ATOM 10442 O O . ALA F 1 118 ? 64.844 -11.358 64.233 1.00 65.05 ? 118 ALA F O 1 +ATOM 10443 C CB . ALA F 1 118 ? 62.703 -9.625 62.815 1.00 138.49 ? 118 ALA F CB 1 +ATOM 10444 N N . ALA F 1 119 ? 63.816 -12.643 62.659 1.00 74.98 ? 119 ALA F N 1 +ATOM 10445 C CA . ALA F 1 119 ? 64.916 -13.590 62.510 1.00 92.16 ? 119 ALA F CA 1 +ATOM 10446 C C . ALA F 1 119 ? 66.026 -13.071 61.590 1.00 88.17 ? 119 ALA F C 1 +ATOM 10447 O O . ALA F 1 119 ? 65.773 -12.241 60.726 1.00 66.18 ? 119 ALA F O 1 +ATOM 10448 C CB . ALA F 1 119 ? 64.378 -14.892 61.975 1.00 84.82 ? 119 ALA F CB 1 +ATOM 10449 N N . ASN F 1 120 ? 67.247 -13.581 61.765 1.00 95.14 ? 120 ASN F N 1 +ATOM 10450 C CA . ASN F 1 120 ? 68.326 -13.241 60.848 1.00 115.93 ? 120 ASN F CA 1 +ATOM 10451 C C . ASN F 1 120 ? 68.545 -14.306 59.791 1.00 137.65 ? 120 ASN F C 1 +ATOM 10452 O O . ASN F 1 120 ? 68.765 -14.011 58.614 1.00 161.28 ? 120 ASN F O 1 +ATOM 10453 C CB . ASN F 1 120 ? 69.649 -13.000 61.568 1.00 126.51 ? 120 ASN F CB 1 +ATOM 10454 C CG . ASN F 1 120 ? 70.754 -12.568 60.599 1.00 144.62 ? 120 ASN F CG 1 +ATOM 10455 O OD1 . ASN F 1 120 ? 71.897 -12.990 60.741 1.00 180.59 ? 120 ASN F OD1 1 +ATOM 10456 N ND2 . ASN F 1 120 ? 70.405 -11.753 59.580 1.00 128.38 ? 120 ASN F ND2 1 +ATOM 10457 N N . ILE F 1 121 ? 68.599 -15.556 60.225 1.00 116.36 ? 121 ILE F N 1 +ATOM 10458 C CA . ILE F 1 121 ? 68.688 -16.647 59.278 1.00 80.72 ? 121 ILE F CA 1 +ATOM 10459 C C . ILE F 1 121 ? 67.386 -17.373 59.337 1.00 67.66 ? 121 ILE F C 1 +ATOM 10460 O O . ILE F 1 121 ? 66.790 -17.514 60.391 1.00 58.17 ? 121 ILE F O 1 +ATOM 10461 C CB . ILE F 1 121 ? 69.875 -17.601 59.564 1.00 74.17 ? 121 ILE F CB 1 +ATOM 10462 C CG1 . ILE F 1 121 ? 69.623 -18.496 60.797 1.00 64.40 ? 121 ILE F CG1 1 +ATOM 10463 C CG2 . ILE F 1 121 ? 71.195 -16.813 59.696 1.00 64.59 ? 121 ILE F CG2 1 +ATOM 10464 C CD1 . ILE F 1 121 ? 69.415 -19.962 60.475 1.00 55.08 ? 121 ILE F CD1 1 +ATOM 10465 N N . MET F 1 122 ? 66.910 -17.802 58.186 1.00 83.79 ? 122 MET F N 1 +ATOM 10466 C CA . MET F 1 122 ? 65.802 -18.744 58.183 1.00 110.74 ? 122 MET F CA 1 +ATOM 10467 C C . MET F 1 122 ? 66.183 -20.029 57.459 1.00 105.93 ? 122 MET F C 1 +ATOM 10468 O O . MET F 1 122 ? 67.025 -20.001 56.566 1.00 107.66 ? 122 MET F O 1 +ATOM 10469 C CB . MET F 1 122 ? 64.567 -18.096 57.573 1.00 118.60 ? 122 MET F CB 1 +ATOM 10470 C CG . MET F 1 122 ? 64.737 -17.584 56.157 1.00 121.48 ? 122 MET F CG 1 +ATOM 10471 S SD . MET F 1 122 ? 63.156 -17.647 55.304 1.00 89.88 ? 122 MET F SD 1 +ATOM 10472 C CE . MET F 1 122 ? 63.627 -18.236 53.682 1.00 66.71 ? 122 MET F CE 1 +ATOM 10473 N N . VAL F 1 123 ? 65.727 -21.151 57.986 1.00 97.59 ? 123 VAL F N 1 +ATOM 10474 C CA . VAL F 1 123 ? 66.117 -22.448 57.451 1.00 98.89 ? 123 VAL F CA 1 +ATOM 10475 C C . VAL F 1 123 ? 64.867 -23.120 56.882 1.00 104.33 ? 123 VAL F C 1 +ATOM 10476 O O . VAL F 1 123 ? 63.890 -23.285 57.587 1.00 92.62 ? 123 VAL F O 1 +ATOM 10477 C CB . VAL F 1 123 ? 66.839 -23.357 58.494 1.00 86.37 ? 123 VAL F CB 1 +ATOM 10478 C CG1 . VAL F 1 123 ? 66.167 -23.241 59.862 1.00 106.21 ? 123 VAL F CG1 1 +ATOM 10479 C CG2 . VAL F 1 123 ? 66.860 -24.823 58.016 1.00 114.32 ? 123 VAL F CG2 1 +ATOM 10480 N N . GLU F 1 124 ? 64.972 -23.599 55.664 1.00 121.71 ? 124 GLU F N 1 +ATOM 10481 C CA . GLU F 1 124 ? 63.908 -24.378 55.110 1.00 123.85 ? 124 GLU F CA 1 +ATOM 10482 C C . GLU F 1 124 ? 64.483 -25.603 54.460 1.00 139.45 ? 124 GLU F C 1 +ATOM 10483 O O . GLU F 1 124 ? 65.690 -25.722 54.289 1.00 153.74 ? 124 GLU F O 1 +ATOM 10484 C CB . GLU F 1 124 ? 63.102 -23.573 54.106 1.00 153.72 ? 124 GLU F CB 1 +ATOM 10485 C CG . GLU F 1 124 ? 63.852 -22.483 53.347 1.00 173.99 ? 124 GLU F CG 1 +ATOM 10486 C CD . GLU F 1 124 ? 62.904 -21.482 52.675 1.00 176.55 ? 124 GLU F CD 1 +ATOM 10487 O OE1 . GLU F 1 124 ? 61.833 -21.183 53.227 1.00 113.32 ? 124 GLU F OE1 1 +ATOM 10488 O OE2 . GLU F 1 124 ? 63.220 -21.012 51.564 1.00 197.97 ? 124 GLU F OE2 1 +ATOM 10489 N N . GLY F 1 125 ? 63.608 -26.515 54.078 1.00 147.00 ? 125 GLY F N 1 +ATOM 10490 C CA . GLY F 1 125 ? 64.045 -27.773 53.507 1.00 139.41 ? 125 GLY F CA 1 +ATOM 10491 C C . GLY F 1 125 ? 62.895 -28.568 52.958 1.00 124.36 ? 125 GLY F C 1 +ATOM 10492 O O . GLY F 1 125 ? 61.807 -28.036 52.712 1.00 141.96 ? 125 GLY F O 1 +ATOM 10493 N N . SER F 1 126 ? 63.125 -29.859 52.772 1.00 102.75 ? 126 SER F N 1 +ATOM 10494 C CA . SER F 1 126 ? 62.115 -30.703 52.153 1.00 122.77 ? 126 SER F CA 1 +ATOM 10495 C C . SER F 1 126 ? 62.376 -32.150 52.487 1.00 94.79 ? 126 SER F C 1 +ATOM 10496 O O . SER F 1 126 ? 63.512 -32.546 52.685 1.00 150.60 ? 126 SER F O 1 +ATOM 10497 C CB . SER F 1 126 ? 62.146 -30.550 50.632 1.00 142.43 ? 126 SER F CB 1 +ATOM 10498 O OG . SER F 1 126 ? 62.560 -29.250 50.226 1.00 136.29 ? 126 SER F OG 1 +ATOM 10499 N N . ILE F 1 127 ? 61.321 -32.941 52.599 1.00 76.06 ? 127 ILE F N 1 +ATOM 10500 C CA . ILE F 1 127 ? 61.497 -34.372 52.623 1.00 60.11 ? 127 ILE F CA 1 +ATOM 10501 C C . ILE F 1 127 ? 61.714 -34.738 51.174 1.00 67.75 ? 127 ILE F C 1 +ATOM 10502 O O . ILE F 1 127 ? 60.780 -34.880 50.405 1.00 81.10 ? 127 ILE F O 1 +ATOM 10503 C CB . ILE F 1 127 ? 60.320 -35.138 53.254 1.00 55.50 ? 127 ILE F CB 1 +ATOM 10504 C CG1 . ILE F 1 127 ? 60.204 -34.821 54.755 1.00 54.94 ? 127 ILE F CG1 1 +ATOM 10505 C CG2 . ILE F 1 127 ? 60.469 -36.645 53.063 1.00 50.05 ? 127 ILE F CG2 1 +ATOM 10506 C CD1 . ILE F 1 127 ? 58.763 -34.861 55.276 1.00 73.94 ? 127 ILE F CD1 1 +ATOM 10507 N N . ILE F 1 128 ? 62.966 -34.994 50.850 1.00 92.75 ? 128 ILE F N 1 +ATOM 10508 C CA . ILE F 1 128 ? 63.369 -35.465 49.543 1.00 129.01 ? 128 ILE F CA 1 +ATOM 10509 C C . ILE F 1 128 ? 63.359 -37.004 49.587 1.00 142.62 ? 128 ILE F C 1 +ATOM 10510 O O . ILE F 1 128 ? 64.230 -37.656 50.174 1.00 268.39 ? 128 ILE F O 1 +ATOM 10511 C CB . ILE F 1 128 ? 64.751 -34.881 49.180 1.00 160.00 ? 128 ILE F CB 1 +ATOM 10512 C CG1 . ILE F 1 128 ? 65.791 -35.207 50.262 1.00 158.23 ? 128 ILE F CG1 1 +ATOM 10513 C CG2 . ILE F 1 128 ? 64.666 -33.360 49.122 1.00 158.36 ? 128 ILE F CG2 1 +ATOM 10514 C CD1 . ILE F 1 128 ? 67.211 -35.189 49.736 1.00 190.07 ? 128 ILE F CD1 1 +ATOM 10515 N N . GLY F 1 129 ? 62.276 -37.587 49.091 1.00 108.24 ? 129 GLY F N 1 +ATOM 10516 C CA . GLY F 1 129 ? 62.252 -39.002 48.807 1.00 107.57 ? 129 GLY F CA 1 +ATOM 10517 C C . GLY F 1 129 ? 61.847 -39.924 49.952 1.00 123.13 ? 129 GLY F C 1 +ATOM 10518 O O . GLY F 1 129 ? 62.352 -39.840 51.091 1.00 180.19 ? 129 GLY F O 1 +ATOM 10519 N N . TYR F 1 130 ? 61.024 -40.900 49.590 1.00 126.52 ? 130 TYR F N 1 +ATOM 10520 C CA . TYR F 1 130 ? 60.834 -42.121 50.376 1.00 97.81 ? 130 TYR F CA 1 +ATOM 10521 C C . TYR F 1 130 ? 60.730 -43.272 49.397 1.00 110.09 ? 130 TYR F C 1 +ATOM 10522 O O . TYR F 1 130 ? 59.790 -43.332 48.621 1.00 155.27 ? 130 TYR F O 1 +ATOM 10523 C CB . TYR F 1 130 ? 59.561 -42.011 51.194 1.00 62.73 ? 130 TYR F CB 1 +ATOM 10524 C CG . TYR F 1 130 ? 59.185 -43.242 51.958 1.00 67.34 ? 130 TYR F CG 1 +ATOM 10525 C CD1 . TYR F 1 130 ? 58.817 -44.401 51.308 1.00 70.57 ? 130 TYR F CD1 1 +ATOM 10526 C CD2 . TYR F 1 130 ? 59.112 -43.214 53.359 1.00 98.75 ? 130 TYR F CD2 1 +ATOM 10527 C CE1 . TYR F 1 130 ? 58.397 -45.518 52.032 1.00 92.00 ? 130 TYR F CE1 1 +ATOM 10528 C CE2 . TYR F 1 130 ? 58.712 -44.324 54.089 1.00 102.23 ? 130 TYR F CE2 1 +ATOM 10529 C CZ . TYR F 1 130 ? 58.359 -45.471 53.421 1.00 85.40 ? 130 TYR F CZ 1 +ATOM 10530 O OH . TYR F 1 130 ? 57.963 -46.553 54.166 1.00 69.49 ? 130 TYR F OH 1 +ATOM 10531 N N . GLU F 1 131 ? 61.780 -44.076 49.302 1.00 120.08 ? 131 GLU F N 1 +ATOM 10532 C CA . GLU F 1 131 ? 61.714 -45.290 48.511 1.00 111.09 ? 131 GLU F CA 1 +ATOM 10533 C C . GLU F 1 131 ? 61.340 -46.444 49.439 1.00 116.58 ? 131 GLU F C 1 +ATOM 10534 O O . GLU F 1 131 ? 61.714 -46.443 50.620 1.00 114.70 ? 131 GLU F O 1 +ATOM 10535 C CB . GLU F 1 131 ? 63.047 -45.515 47.819 1.00 110.20 ? 131 GLU F CB 1 +ATOM 10536 C CG . GLU F 1 131 ? 63.048 -46.628 46.789 1.00 139.33 ? 131 GLU F CG 1 +ATOM 10537 C CD . GLU F 1 131 ? 62.606 -46.175 45.402 1.00 146.55 ? 131 GLU F CD 1 +ATOM 10538 O OE1 . GLU F 1 131 ? 62.836 -44.992 45.055 1.00 123.00 ? 131 GLU F OE1 1 +ATOM 10539 O OE2 . GLU F 1 131 ? 62.100 -47.029 44.632 1.00 135.24 ? 131 GLU F OE2 1 +ATOM 10540 N N . SER F 1 132 ? 60.606 -47.422 48.915 1.00 105.30 ? 132 SER F N 1 +ATOM 10541 C CA . SER F 1 132 ? 60.050 -48.475 49.766 1.00 122.74 ? 132 SER F CA 1 +ATOM 10542 C C . SER F 1 132 ? 60.551 -49.872 49.367 1.00 132.79 ? 132 SER F C 1 +ATOM 10543 O O . SER F 1 132 ? 60.696 -50.170 48.182 1.00 147.71 ? 132 SER F O 1 +ATOM 10544 C CB . SER F 1 132 ? 58.524 -48.432 49.726 1.00 124.89 ? 132 SER F CB 1 +ATOM 10545 O OG . SER F 1 132 ? 57.999 -49.584 49.085 1.00 152.10 ? 132 SER F OG 1 +ATOM 10546 N N . ASN F 1 133 ? 60.782 -50.729 50.365 1.00 123.17 ? 133 ASN F N 1 +ATOM 10547 C CA . ASN F 1 133 ? 61.482 -52.015 50.171 1.00 94.32 ? 133 ASN F CA 1 +ATOM 10548 C C . ASN F 1 133 ? 62.740 -51.860 49.345 1.00 107.57 ? 133 ASN F C 1 +ATOM 10549 O O . ASN F 1 133 ? 62.888 -52.474 48.278 1.00 97.48 ? 133 ASN F O 1 +ATOM 10550 C CB . ASN F 1 133 ? 60.569 -53.032 49.526 1.00 89.38 ? 133 ASN F CB 1 +ATOM 10551 C CG . ASN F 1 133 ? 59.343 -53.299 50.360 1.00 123.46 ? 133 ASN F CG 1 +ATOM 10552 O OD1 . ASN F 1 133 ? 59.358 -53.199 51.596 1.00 113.49 ? 133 ASN F OD1 1 +ATOM 10553 N ND2 . ASN F 1 133 ? 58.253 -53.624 49.687 1.00 162.85 ? 133 ASN F ND2 1 +ATOM 10554 N N . VAL F 1 134 ? 63.637 -51.003 49.831 1.00 129.01 ? 134 VAL F N 1 +ATOM 10555 C CA . VAL F 1 134 ? 64.895 -50.717 49.149 1.00 139.21 ? 134 VAL F CA 1 +ATOM 10556 C C . VAL F 1 134 ? 65.739 -51.979 49.253 1.00 141.62 ? 134 VAL F C 1 +ATOM 10557 O O . VAL F 1 134 ? 66.454 -52.345 48.313 1.00 95.73 ? 134 VAL F O 1 +ATOM 10558 C CB . VAL F 1 134 ? 65.619 -49.503 49.785 1.00 108.94 ? 134 VAL F CB 1 +ATOM 10559 C CG1 . VAL F 1 134 ? 66.891 -49.181 49.020 1.00 117.36 ? 134 VAL F CG1 1 +ATOM 10560 C CG2 . VAL F 1 134 ? 64.704 -48.285 49.781 1.00 126.15 ? 134 VAL F CG2 1 +ATOM 10561 N N . LYS F 1 135 ? 65.580 -52.676 50.380 1.00 145.07 ? 135 LYS F N 1 +ATOM 10562 C CA . LYS F 1 135 ? 66.036 -54.063 50.495 1.00 133.46 ? 135 LYS F CA 1 +ATOM 10563 C C . LYS F 1 135 ? 65.042 -54.931 51.248 1.00 94.68 ? 135 LYS F C 1 +ATOM 10564 O O . LYS F 1 135 ? 64.153 -54.438 51.952 1.00 55.92 ? 135 LYS F O 1 +ATOM 10565 C CB . LYS F 1 135 ? 67.358 -54.131 51.245 1.00 210.68 ? 135 LYS F CB 1 +ATOM 10566 C CG . LYS F 1 135 ? 68.500 -53.403 50.558 1.00 255.85 ? 135 LYS F CG 1 +ATOM 10567 C CD . LYS F 1 135 ? 69.743 -53.426 51.429 1.00 254.79 ? 135 LYS F CD 1 +ATOM 10568 C CE . LYS F 1 135 ? 70.894 -52.692 50.774 1.00 225.60 ? 135 LYS F CE 1 +ATOM 10569 N NZ . LYS F 1 135 ? 72.183 -53.130 51.361 1.00 224.61 ? 135 LYS F NZ 1 +ATOM 10570 N N . SER F 1 136 ? 65.153 -56.233 51.015 1.00 101.82 ? 136 SER F N 1 +ATOM 10571 C CA . SER F 1 136 ? 64.228 -57.196 51.601 1.00 114.64 ? 136 SER F CA 1 +ATOM 10572 C C . SER F 1 136 ? 64.752 -58.604 51.489 1.00 115.21 ? 136 SER F C 1 +ATOM 10573 O O . SER F 1 136 ? 65.582 -58.913 50.623 1.00 87.31 ? 136 SER F O 1 +ATOM 10574 C CB . SER F 1 136 ? 62.844 -57.127 50.940 1.00 151.02 ? 136 SER F CB 1 +ATOM 10575 O OG . SER F 1 136 ? 62.416 -58.392 50.452 1.00 154.30 ? 136 SER F OG 1 +ATOM 10576 N N . GLY F 1 137 ? 64.282 -59.453 52.393 1.00 123.33 ? 137 GLY F N 1 +ATOM 10577 C CA . GLY F 1 137 ? 64.715 -60.841 52.401 1.00 137.98 ? 137 GLY F CA 1 +ATOM 10578 C C . GLY F 1 137 ? 63.879 -61.724 53.302 1.00 122.63 ? 137 GLY F C 1 +ATOM 10579 O O . GLY F 1 137 ? 63.004 -61.250 54.014 1.00 73.30 ? 137 GLY F O 1 +ATOM 10580 N N . GLY F 1 138 ? 64.158 -63.020 53.253 1.00 112.48 ? 138 GLY F N 1 +ATOM 10581 C CA . GLY F 1 138 ? 63.447 -63.961 54.079 1.00 106.26 ? 138 GLY F CA 1 +ATOM 10582 C C . GLY F 1 138 ? 64.159 -65.284 54.167 1.00 128.98 ? 138 GLY F C 1 +ATOM 10583 O O . GLY F 1 138 ? 64.812 -65.728 53.212 1.00 107.10 ? 138 GLY F O 1 +ATOM 10584 N N . VAL F 1 139 ? 64.043 -65.915 55.333 1.00 149.40 ? 139 VAL F N 1 +ATOM 10585 C CA . VAL F 1 139 ? 64.605 -67.247 55.549 1.00 142.10 ? 139 VAL F CA 1 +ATOM 10586 C C . VAL F 1 139 ? 63.617 -68.104 56.335 1.00 114.49 ? 139 VAL F C 1 +ATOM 10587 O O . VAL F 1 139 ? 63.176 -67.723 57.413 1.00 77.07 ? 139 VAL F O 1 +ATOM 10588 C CB . VAL F 1 139 ? 65.944 -67.196 56.316 1.00 122.77 ? 139 VAL F CB 1 +ATOM 10589 C CG1 . VAL F 1 139 ? 66.413 -68.602 56.625 1.00 124.56 ? 139 VAL F CG1 1 +ATOM 10590 C CG2 . VAL F 1 139 ? 67.001 -66.437 55.524 1.00 116.06 ? 139 VAL F CG2 1 +ATOM 10591 N N . GLY F 1 140 ? 63.289 -69.260 55.772 1.00 110.04 ? 140 GLY F N 1 +ATOM 10592 C CA . GLY F 1 140 ? 62.331 -70.155 56.376 1.00 114.44 ? 140 GLY F CA 1 +ATOM 10593 C C . GLY F 1 140 ? 62.596 -71.610 56.049 1.00 149.20 ? 140 GLY F C 1 +ATOM 10594 O O . GLY F 1 140 ? 63.045 -71.961 54.948 1.00 127.81 ? 140 GLY F O 1 +ATOM 10595 N N . ALA F 1 141 ? 62.302 -72.472 57.011 1.00 182.49 ? 141 ALA F N 1 +ATOM 10596 C CA . ALA F 1 141 ? 62.417 -73.908 56.790 1.00 190.47 ? 141 ALA F CA 1 +ATOM 10597 C C . ALA F 1 141 ? 61.295 -74.662 57.491 1.00 225.03 ? 141 ALA F C 1 +ATOM 10598 O O . ALA F 1 141 ? 60.887 -74.321 58.603 1.00 203.65 ? 141 ALA F O 1 +ATOM 10599 C CB . ALA F 1 141 ? 63.778 -74.417 57.237 1.00 157.92 ? 141 ALA F CB 1 +ATOM 10600 N N . ARG F 1 142 ? 60.772 -75.668 56.806 1.00 245.68 ? 142 ARG F N 1 +ATOM 10601 C CA . ARG F 1 142 ? 59.841 -76.583 57.424 1.00 225.01 ? 142 ARG F CA 1 +ATOM 10602 C C . ARG F 1 142 ? 60.329 -78.003 57.193 1.00 239.23 ? 142 ARG F C 1 +ATOM 10603 O O . ARG F 1 142 ? 60.920 -78.308 56.154 1.00 221.69 ? 142 ARG F O 1 +ATOM 10604 C CB . ARG F 1 142 ? 58.430 -76.396 56.875 1.00 190.04 ? 142 ARG F CB 1 +ATOM 10605 C CG . ARG F 1 142 ? 57.403 -77.276 57.573 1.00 184.53 ? 142 ARG F CG 1 +ATOM 10606 C CD . ARG F 1 142 ? 56.103 -76.544 57.851 1.00 206.08 ? 142 ARG F CD 1 +ATOM 10607 N NE . ARG F 1 142 ? 55.242 -76.523 56.670 1.00 227.86 ? 142 ARG F NE 1 +ATOM 10608 C CZ . ARG F 1 142 ? 54.301 -75.614 56.427 1.00 226.61 ? 142 ARG F CZ 1 +ATOM 10609 N NH1 . ARG F 1 142 ? 54.088 -74.620 57.280 1.00 218.67 ? 142 ARG F NH1 1 +ATOM 10610 N NH2 . ARG F 1 142 ? 53.571 -75.697 55.318 1.00 221.16 ? 142 ARG F NH2 1 +ATOM 10611 N N . TYR F 1 143 ? 60.130 -78.847 58.198 1.00 248.18 ? 143 TYR F N 1 +ATOM 10612 C CA . TYR F 1 143 ? 60.694 -80.195 58.207 1.00 216.37 ? 143 TYR F CA 1 +ATOM 10613 C C . TYR F 1 143 ? 59.628 -81.243 58.550 1.00 174.57 ? 143 TYR F C 1 +ATOM 10614 O O . TYR F 1 143 ? 59.470 -81.647 59.704 1.00 104.88 ? 143 TYR F O 1 +ATOM 10615 C CB . TYR F 1 143 ? 61.854 -80.259 59.203 1.00 206.63 ? 143 TYR F CB 1 +ATOM 10616 C CG . TYR F 1 143 ? 62.598 -81.555 59.179 1.00 204.48 ? 143 TYR F CG 1 +ATOM 10617 C CD1 . TYR F 1 143 ? 63.431 -81.874 58.118 1.00 186.91 ? 143 TYR F CD1 1 +ATOM 10618 C CD2 . TYR F 1 143 ? 62.473 -82.464 60.220 1.00 223.71 ? 143 TYR F CD2 1 +ATOM 10619 C CE1 . TYR F 1 143 ? 64.123 -83.069 58.088 1.00 207.87 ? 143 TYR F CE1 1 +ATOM 10620 C CE2 . TYR F 1 143 ? 63.171 -83.660 60.210 1.00 222.64 ? 143 TYR F CE2 1 +ATOM 10621 C CZ . TYR F 1 143 ? 63.987 -83.960 59.136 1.00 235.00 ? 143 TYR F CZ 1 +ATOM 10622 O OH . TYR F 1 143 ? 64.670 -85.154 59.110 1.00 294.95 ? 143 TYR F OH 1 +ATOM 10623 N N . GLY F 1 145 ? 57.125 -81.564 59.559 1.00 152.13 ? 145 GLY F N 1 +ATOM 10624 C CA . GLY F 1 145 ? 55.977 -81.140 60.349 1.00 161.83 ? 145 GLY F CA 1 +ATOM 10625 C C . GLY F 1 145 ? 56.172 -79.813 61.077 1.00 218.79 ? 145 GLY F C 1 +ATOM 10626 O O . GLY F 1 145 ? 55.193 -79.134 61.383 1.00 212.08 ? 145 GLY F O 1 +ATOM 10627 N N . ILE F 1 146 ? 57.423 -79.431 61.348 1.00 264.64 ? 146 ILE F N 1 +ATOM 10628 C CA . ILE F 1 146 ? 57.741 -78.256 62.190 1.00 239.26 ? 146 ILE F CA 1 +ATOM 10629 C C . ILE F 1 146 ? 58.426 -77.189 61.332 1.00 232.16 ? 146 ILE F C 1 +ATOM 10630 O O . ILE F 1 146 ? 59.280 -77.518 60.516 1.00 179.28 ? 146 ILE F O 1 +ATOM 10631 C CB . ILE F 1 146 ? 58.664 -78.630 63.387 1.00 193.47 ? 146 ILE F CB 1 +ATOM 10632 C CG1 . ILE F 1 146 ? 58.259 -79.993 63.975 1.00 189.73 ? 146 ILE F CG1 1 +ATOM 10633 C CG2 . ILE F 1 146 ? 58.619 -77.554 64.467 1.00 138.33 ? 146 ILE F CG2 1 +ATOM 10634 C CD1 . ILE F 1 146 ? 59.070 -81.164 63.458 1.00 161.96 ? 146 ILE F CD1 1 +ATOM 10635 N N . GLY F 1 147 ? 58.056 -75.919 61.503 1.00 226.50 ? 147 GLY F N 1 +ATOM 10636 C CA . GLY F 1 147 ? 58.618 -74.862 60.656 1.00 200.28 ? 147 GLY F CA 1 +ATOM 10637 C C . GLY F 1 147 ? 58.728 -73.482 61.281 1.00 181.95 ? 147 GLY F C 1 +ATOM 10638 O O . GLY F 1 147 ? 58.011 -73.142 62.218 1.00 115.62 ? 147 GLY F O 1 +ATOM 10639 N N . ALA F 1 148 ? 59.659 -72.692 60.762 1.00 187.21 ? 148 ALA F N 1 +ATOM 10640 C CA . ALA F 1 148 ? 59.765 -71.291 61.144 1.00 167.94 ? 148 ALA F CA 1 +ATOM 10641 C C . ALA F 1 148 ? 60.260 -70.468 59.966 1.00 158.25 ? 148 ALA F C 1 +ATOM 10642 O O . ALA F 1 148 ? 60.722 -71.015 58.957 1.00 123.38 ? 148 ALA F O 1 +ATOM 10643 C CB . ALA F 1 148 ? 60.687 -71.124 62.344 1.00 152.79 ? 148 ALA F CB 1 +ATOM 10644 N N . ASP F 1 149 ? 60.119 -69.154 60.086 1.00 148.27 ? 149 ASP F N 1 +ATOM 10645 C CA . ASP F 1 149 ? 60.597 -68.258 59.050 1.00 153.36 ? 149 ASP F CA 1 +ATOM 10646 C C . ASP F 1 149 ? 60.650 -66.822 59.558 1.00 135.45 ? 149 ASP F C 1 +ATOM 10647 O O . ASP F 1 149 ? 59.851 -66.419 60.410 1.00 85.73 ? 149 ASP F O 1 +ATOM 10648 C CB . ASP F 1 149 ? 59.714 -68.357 57.800 1.00 181.80 ? 149 ASP F CB 1 +ATOM 10649 C CG . ASP F 1 149 ? 58.444 -67.564 57.925 1.00 198.46 ? 149 ASP F CG 1 +ATOM 10650 O OD1 . ASP F 1 149 ? 57.533 -68.014 58.642 1.00 181.00 ? 149 ASP F OD1 1 +ATOM 10651 O OD2 . ASP F 1 149 ? 58.350 -66.502 57.287 1.00 208.04 ? 149 ASP F OD2 1 +ATOM 10652 N N . THR F 1 150 ? 61.608 -66.057 59.049 1.00 139.85 ? 150 THR F N 1 +ATOM 10653 C CA . THR F 1 150 ? 61.566 -64.605 59.212 1.00 137.88 ? 150 THR F CA 1 +ATOM 10654 C C . THR F 1 150 ? 61.590 -63.941 57.846 1.00 148.71 ? 150 THR F C 1 +ATOM 10655 O O . THR F 1 150 ? 62.055 -64.519 56.855 1.00 97.58 ? 150 THR F O 1 +ATOM 10656 C CB . THR F 1 150 ? 62.734 -64.051 60.055 1.00 123.27 ? 150 THR F CB 1 +ATOM 10657 O OG1 . THR F 1 150 ? 63.977 -64.397 59.431 1.00 157.72 ? 150 THR F OG1 1 +ATOM 10658 C CG2 . THR F 1 150 ? 62.691 -64.594 61.456 1.00 109.15 ? 150 THR F CG2 1 +ATOM 10659 N N . GLN F 1 151 ? 61.033 -62.739 57.798 1.00 152.74 ? 151 GLN F N 1 +ATOM 10660 C CA . GLN F 1 151 ? 61.081 -61.916 56.613 1.00 152.26 ? 151 GLN F CA 1 +ATOM 10661 C C . GLN F 1 151 ? 61.387 -60.498 57.037 1.00 133.83 ? 151 GLN F C 1 +ATOM 10662 O O . GLN F 1 151 ? 60.935 -60.059 58.077 1.00 68.94 ? 151 GLN F O 1 +ATOM 10663 C CB . GLN F 1 151 ? 59.735 -61.982 55.900 1.00 167.20 ? 151 GLN F CB 1 +ATOM 10664 C CG . GLN F 1 151 ? 59.505 -63.309 55.202 1.00 185.53 ? 151 GLN F CG 1 +ATOM 10665 C CD . GLN F 1 151 ? 58.047 -63.579 54.928 1.00 182.68 ? 151 GLN F CD 1 +ATOM 10666 O OE1 . GLN F 1 151 ? 57.306 -62.665 54.579 1.00 170.76 ? 151 GLN F OE1 1 +ATOM 10667 N NE2 . GLN F 1 151 ? 57.615 -64.827 55.134 1.00 185.70 ? 151 GLN F NE2 1 +ATOM 10668 N N . TYR F 1 152 ? 62.192 -59.791 56.256 1.00 140.04 ? 152 TYR F N 1 +ATOM 10669 C CA . TYR F 1 152 ? 62.497 -58.409 56.583 1.00 139.11 ? 152 TYR F CA 1 +ATOM 10670 C C . TYR F 1 152 ? 62.438 -57.515 55.362 1.00 148.37 ? 152 TYR F C 1 +ATOM 10671 O O . TYR F 1 152 ? 62.719 -57.953 54.237 1.00 88.06 ? 152 TYR F O 1 +ATOM 10672 C CB . TYR F 1 152 ? 63.858 -58.315 57.264 1.00 137.74 ? 152 TYR F CB 1 +ATOM 10673 C CG . TYR F 1 152 ? 65.021 -57.806 56.416 1.00 140.09 ? 152 TYR F CG 1 +ATOM 10674 C CD1 . TYR F 1 152 ? 65.494 -58.507 55.312 1.00 127.96 ? 152 TYR F CD1 1 +ATOM 10675 C CD2 . TYR F 1 152 ? 65.687 -56.651 56.775 1.00 138.60 ? 152 TYR F CD2 1 +ATOM 10676 C CE1 . TYR F 1 152 ? 66.542 -58.011 54.540 1.00 133.00 ? 152 TYR F CE1 1 +ATOM 10677 C CE2 . TYR F 1 152 ? 66.783 -56.181 56.056 1.00 129.70 ? 152 TYR F CE2 1 +ATOM 10678 C CZ . TYR F 1 152 ? 67.197 -56.853 54.926 1.00 131.60 ? 152 TYR F CZ 1 +ATOM 10679 O OH . TYR F 1 152 ? 68.272 -56.360 54.197 1.00 111.92 ? 152 TYR F OH 1 +ATOM 10680 N N . GLN F 1 153 ? 62.007 -56.274 55.581 1.00 135.38 ? 153 GLN F N 1 +ATOM 10681 C CA . GLN F 1 153 ? 62.074 -55.266 54.535 1.00 147.51 ? 153 GLN F CA 1 +ATOM 10682 C C . GLN F 1 153 ? 62.597 -53.965 55.107 1.00 107.23 ? 153 GLN F C 1 +ATOM 10683 O O . GLN F 1 153 ? 62.478 -53.720 56.307 1.00 68.85 ? 153 GLN F O 1 +ATOM 10684 C CB . GLN F 1 153 ? 60.691 -55.054 53.912 1.00 179.68 ? 153 GLN F CB 1 +ATOM 10685 C CG . GLN F 1 153 ? 60.125 -56.259 53.147 1.00 194.55 ? 153 GLN F CG 1 +ATOM 10686 C CD . GLN F 1 153 ? 58.693 -55.994 52.650 1.00 188.84 ? 153 GLN F CD 1 +ATOM 10687 O OE1 . GLN F 1 153 ? 57.988 -55.122 53.177 1.00 194.05 ? 153 GLN F OE1 1 +ATOM 10688 N NE2 . GLN F 1 153 ? 58.250 -56.762 51.656 1.00 175.76 ? 153 GLN F NE2 1 +ATOM 10689 N N . LEU F 1 154 ? 63.217 -53.155 54.255 1.00 103.25 ? 154 LEU F N 1 +ATOM 10690 C CA . LEU F 1 154 ? 63.632 -51.836 54.684 1.00 139.82 ? 154 LEU F CA 1 +ATOM 10691 C C . LEU F 1 154 ? 63.497 -50.775 53.598 1.00 159.08 ? 154 LEU F C 1 +ATOM 10692 O O . LEU F 1 154 ? 63.757 -51.023 52.405 1.00 118.15 ? 154 LEU F O 1 +ATOM 10693 C CB . LEU F 1 154 ? 65.064 -51.856 55.228 1.00 164.98 ? 154 LEU F CB 1 +ATOM 10694 C CG . LEU F 1 154 ? 66.178 -52.033 54.189 1.00 200.52 ? 154 LEU F CG 1 +ATOM 10695 C CD1 . LEU F 1 154 ? 66.745 -50.694 53.739 1.00 193.46 ? 154 LEU F CD1 1 +ATOM 10696 C CD2 . LEU F 1 154 ? 67.270 -52.925 54.762 1.00 259.48 ? 154 LEU F CD2 1 +ATOM 10697 N N . ASP F 1 155 ? 63.179 -49.566 54.071 1.00 157.37 ? 155 ASP F N 1 +ATOM 10698 C CA . ASP F 1 155 ? 62.793 -48.423 53.237 1.00 131.68 ? 155 ASP F CA 1 +ATOM 10699 C C . ASP F 1 155 ? 63.790 -47.279 53.466 1.00 102.03 ? 155 ASP F C 1 +ATOM 10700 O O . ASP F 1 155 ? 64.455 -47.249 54.496 1.00 75.22 ? 155 ASP F O 1 +ATOM 10701 C CB . ASP F 1 155 ? 61.359 -47.978 53.599 1.00 125.94 ? 155 ASP F CB 1 +ATOM 10702 C CG . ASP F 1 155 ? 60.381 -49.148 53.702 1.00 152.18 ? 155 ASP F CG 1 +ATOM 10703 O OD1 . ASP F 1 155 ? 60.393 -49.857 54.735 1.00 159.65 ? 155 ASP F OD1 1 +ATOM 10704 O OD2 . ASP F 1 155 ? 59.643 -49.390 52.727 1.00 140.48 ? 155 ASP F OD2 1 +ATOM 10705 N N . GLN F 1 156 ? 63.856 -46.324 52.539 1.00 114.62 ? 156 GLN F N 1 +ATOM 10706 C CA . GLN F 1 156 ? 64.707 -45.136 52.701 1.00 126.69 ? 156 GLN F CA 1 +ATOM 10707 C C . GLN F 1 156 ? 63.910 -43.808 52.820 1.00 134.91 ? 156 GLN F C 1 +ATOM 10708 O O . GLN F 1 156 ? 62.749 -43.729 52.439 1.00 178.92 ? 156 GLN F O 1 +ATOM 10709 C CB . GLN F 1 156 ? 65.653 -45.033 51.522 1.00 101.34 ? 156 GLN F CB 1 +ATOM 10710 C CG . GLN F 1 156 ? 66.766 -44.019 51.705 1.00 123.69 ? 156 GLN F CG 1 +ATOM 10711 C CD . GLN F 1 156 ? 67.890 -44.195 50.693 1.00 111.52 ? 156 GLN F CD 1 +ATOM 10712 O OE1 . GLN F 1 156 ? 67.833 -45.095 49.838 1.00 77.99 ? 156 GLN F OE1 1 +ATOM 10713 N NE2 . GLN F 1 156 ? 68.989 -43.452 50.895 1.00 95.61 ? 156 GLN F NE2 1 +ATOM 10714 N N . ILE F 1 157 ? 64.515 -42.811 53.450 1.00 95.11 ? 157 ILE F N 1 +ATOM 10715 C CA . ILE F 1 157 ? 63.905 -41.524 53.615 1.00 59.19 ? 157 ILE F CA 1 +ATOM 10716 C C . ILE F 1 157 ? 65.037 -40.503 53.673 1.00 60.60 ? 157 ILE F C 1 +ATOM 10717 O O . ILE F 1 157 ? 66.084 -40.734 54.304 1.00 117.54 ? 157 ILE F O 1 +ATOM 10718 C CB . ILE F 1 157 ? 63.016 -41.482 54.877 1.00 52.70 ? 157 ILE F CB 1 +ATOM 10719 C CG1 . ILE F 1 157 ? 61.985 -40.361 54.752 1.00 105.14 ? 157 ILE F CG1 1 +ATOM 10720 C CG2 . ILE F 1 157 ? 63.829 -41.216 56.117 1.00 59.02 ? 157 ILE F CG2 1 +ATOM 10721 C CD1 . ILE F 1 157 ? 60.937 -40.334 55.857 1.00 134.09 ? 157 ILE F CD1 1 +ATOM 10722 N N . ALA F 1 158 ? 64.872 -39.377 53.014 1.00 70.67 ? 158 ALA F N 1 +ATOM 10723 C CA . ALA F 1 158 ? 65.937 -38.374 52.970 1.00 104.92 ? 158 ALA F CA 1 +ATOM 10724 C C . ALA F 1 158 ? 65.381 -36.987 53.168 1.00 89.89 ? 158 ALA F C 1 +ATOM 10725 O O . ALA F 1 158 ? 64.221 -36.732 52.909 1.00 90.84 ? 158 ALA F O 1 +ATOM 10726 C CB . ALA F 1 158 ? 66.718 -38.430 51.657 1.00 116.63 ? 158 ALA F CB 1 +ATOM 10727 N N . VAL F 1 159 ? 66.226 -36.115 53.700 1.00 90.65 ? 159 VAL F N 1 +ATOM 10728 C CA . VAL F 1 159 ? 65.791 -34.805 54.105 1.00 79.53 ? 159 VAL F CA 1 +ATOM 10729 C C . VAL F 1 159 ? 66.859 -33.815 53.672 1.00 62.37 ? 159 VAL F C 1 +ATOM 10730 O O . VAL F 1 159 ? 68.004 -33.911 54.109 1.00 106.59 ? 159 VAL F O 1 +ATOM 10731 C CB . VAL F 1 159 ? 65.473 -34.747 55.653 1.00 89.64 ? 159 VAL F CB 1 +ATOM 10732 C CG1 . VAL F 1 159 ? 65.485 -33.313 56.191 1.00 86.23 ? 159 VAL F CG1 1 +ATOM 10733 C CG2 . VAL F 1 159 ? 64.116 -35.398 55.961 1.00 81.43 ? 159 VAL F CG2 1 +ATOM 10734 N N . ASN F 1 160 ? 66.426 -32.782 52.986 1.00 45.83 ? 160 ASN F N 1 +ATOM 10735 C CA . ASN F 1 160 ? 67.196 -31.589 52.847 1.00 47.87 ? 160 ASN F CA 1 +ATOM 10736 C C . ASN F 1 160 ? 66.834 -30.538 53.928 1.00 49.98 ? 160 ASN F C 1 +ATOM 10737 O O . ASN F 1 160 ? 65.652 -30.217 54.177 1.00 37.60 ? 160 ASN F O 1 +ATOM 10738 C CB . ASN F 1 160 ? 66.968 -31.010 51.468 1.00 53.12 ? 160 ASN F CB 1 +ATOM 10739 C CG . ASN F 1 160 ? 67.958 -29.861 51.151 1.00 62.80 ? 160 ASN F CG 1 +ATOM 10740 O OD1 . ASN F 1 160 ? 68.950 -30.013 50.405 1.00 39.09 ? 160 ASN F OD1 1 +ATOM 10741 N ND2 . ASN F 1 160 ? 67.707 -28.705 51.740 1.00 87.24 ? 160 ASN F ND2 1 +ATOM 10742 N N . LEU F 1 161 ? 67.856 -29.991 54.591 1.00 56.43 ? 161 LEU F N 1 +ATOM 10743 C CA . LEU F 1 161 ? 67.716 -28.715 55.312 1.00 57.85 ? 161 LEU F CA 1 +ATOM 10744 C C . LEU F 1 161 ? 68.709 -27.688 54.770 1.00 46.27 ? 161 LEU F C 1 +ATOM 10745 O O . LEU F 1 161 ? 69.804 -28.025 54.391 1.00 30.91 ? 161 LEU F O 1 +ATOM 10746 C CB . LEU F 1 161 ? 67.926 -28.916 56.809 1.00 57.87 ? 161 LEU F CB 1 +ATOM 10747 C CG . LEU F 1 161 ? 66.908 -29.810 57.497 1.00 73.73 ? 161 LEU F CG 1 +ATOM 10748 C CD1 . LEU F 1 161 ? 67.362 -30.100 58.914 1.00 112.23 ? 161 LEU F CD1 1 +ATOM 10749 C CD2 . LEU F 1 161 ? 65.545 -29.145 57.492 1.00 70.60 ? 161 LEU F CD2 1 +ATOM 10750 N N . ARG F 1 162 ? 68.338 -26.420 54.815 1.00 49.42 ? 162 ARG F N 1 +ATOM 10751 C CA . ARG F 1 162 ? 69.234 -25.399 54.342 1.00 73.11 ? 162 ARG F CA 1 +ATOM 10752 C C . ARG F 1 162 ? 69.048 -24.012 54.986 1.00 71.53 ? 162 ARG F C 1 +ATOM 10753 O O . ARG F 1 162 ? 67.930 -23.501 55.069 1.00 108.24 ? 162 ARG F O 1 +ATOM 10754 C CB . ARG F 1 162 ? 69.186 -25.318 52.805 1.00 91.22 ? 162 ARG F CB 1 +ATOM 10755 C CG . ARG F 1 162 ? 67.863 -24.884 52.155 1.00 89.79 ? 162 ARG F CG 1 +ATOM 10756 C CD . ARG F 1 162 ? 68.099 -24.453 50.689 1.00 74.46 ? 162 ARG F CD 1 +ATOM 10757 N NE . ARG F 1 162 ? 66.927 -23.838 50.047 1.00 69.75 ? 162 ARG F NE 1 +ATOM 10758 C CZ . ARG F 1 162 ? 66.485 -24.068 48.802 1.00 78.33 ? 162 ARG F CZ 1 +ATOM 10759 N NH1 . ARG F 1 162 ? 67.107 -24.886 47.949 1.00 91.73 ? 162 ARG F NH1 1 +ATOM 10760 N NH2 . ARG F 1 162 ? 65.408 -23.413 48.362 1.00 76.28 ? 162 ARG F NH2 1 +ATOM 10761 N N . VAL F 1 163 ? 70.173 -23.405 55.389 1.00 62.11 ? 163 VAL F N 1 +ATOM 10762 C CA . VAL F 1 163 ? 70.195 -22.085 56.008 1.00 58.46 ? 163 VAL F CA 1 +ATOM 10763 C C . VAL F 1 163 ? 70.287 -21.031 54.952 1.00 46.55 ? 163 VAL F C 1 +ATOM 10764 O O . VAL F 1 163 ? 71.235 -21.023 54.179 1.00 41.44 ? 163 VAL F O 1 +ATOM 10765 C CB . VAL F 1 163 ? 71.417 -21.887 56.893 1.00 72.55 ? 163 VAL F CB 1 +ATOM 10766 C CG1 . VAL F 1 163 ? 71.416 -20.475 57.475 1.00 73.71 ? 163 VAL F CG1 1 +ATOM 10767 C CG2 . VAL F 1 163 ? 71.461 -22.961 57.986 1.00 96.94 ? 163 VAL F CG2 1 +ATOM 10768 N N . VAL F 1 164 ? 69.304 -20.134 54.961 1.00 39.34 ? 164 VAL F N 1 +ATOM 10769 C CA . VAL F 1 164 ? 69.244 -19.035 54.052 1.00 44.49 ? 164 VAL F CA 1 +ATOM 10770 C C . VAL F 1 164 ? 69.432 -17.738 54.788 1.00 41.44 ? 164 VAL F C 1 +ATOM 10771 O O . VAL F 1 164 ? 68.860 -17.534 55.843 1.00 35.04 ? 164 VAL F O 1 +ATOM 10772 C CB . VAL F 1 164 ? 67.895 -18.956 53.370 1.00 61.84 ? 164 VAL F CB 1 +ATOM 10773 C CG1 . VAL F 1 164 ? 67.852 -17.753 52.416 1.00 96.48 ? 164 VAL F CG1 1 +ATOM 10774 C CG2 . VAL F 1 164 ? 67.633 -20.225 52.589 1.00 77.61 ? 164 VAL F CG2 1 +ATOM 10775 N N . ASN F 1 165 ? 70.254 -16.869 54.214 1.00 47.26 ? 165 ASN F N 1 +ATOM 10776 C CA . ASN F 1 165 ? 70.549 -15.589 54.832 1.00 70.35 ? 165 ASN F CA 1 +ATOM 10777 C C . ASN F 1 165 ? 69.525 -14.565 54.414 1.00 88.93 ? 165 ASN F C 1 +ATOM 10778 O O . ASN F 1 165 ? 69.403 -14.261 53.229 1.00 92.13 ? 165 ASN F O 1 +ATOM 10779 C CB . ASN F 1 165 ? 71.951 -15.078 54.452 1.00 97.00 ? 165 ASN F CB 1 +ATOM 10780 C CG . ASN F 1 165 ? 72.369 -13.866 55.276 1.00 98.96 ? 165 ASN F CG 1 +ATOM 10781 O OD1 . ASN F 1 165 ? 71.676 -13.491 56.220 1.00 82.24 ? 165 ASN F OD1 1 +ATOM 10782 N ND2 . ASN F 1 165 ? 73.443 -13.210 54.870 1.00 100.59 ? 165 ASN F ND2 1 +ATOM 10783 N N . VAL F 1 166 ? 68.805 -14.035 55.401 1.00 101.75 ? 166 VAL F N 1 +ATOM 10784 C CA . VAL F 1 166 ? 67.717 -13.111 55.158 1.00 80.22 ? 166 VAL F CA 1 +ATOM 10785 C C . VAL F 1 166 ? 68.256 -11.890 54.474 1.00 55.53 ? 166 VAL F C 1 +ATOM 10786 O O . VAL F 1 166 ? 67.618 -11.352 53.583 1.00 66.09 ? 166 VAL F O 1 +ATOM 10787 C CB . VAL F 1 166 ? 67.018 -12.720 56.481 1.00 83.45 ? 166 VAL F CB 1 +ATOM 10788 C CG1 . VAL F 1 166 ? 66.336 -11.361 56.369 1.00 90.85 ? 166 VAL F CG1 1 +ATOM 10789 C CG2 . VAL F 1 166 ? 66.036 -13.827 56.898 1.00 82.98 ? 166 VAL F CG2 1 +ATOM 10790 N N . SER F 1 167 ? 69.431 -11.475 54.885 1.00 48.51 ? 167 SER F N 1 +ATOM 10791 C CA . SER F 1 167 ? 69.956 -10.227 54.438 1.00 70.07 ? 167 SER F CA 1 +ATOM 10792 C C . SER F 1 167 ? 70.373 -10.250 52.961 1.00 61.54 ? 167 SER F C 1 +ATOM 10793 O O . SER F 1 167 ? 70.662 -9.164 52.396 1.00 93.99 ? 167 SER F O 1 +ATOM 10794 C CB . SER F 1 167 ? 71.123 -9.806 55.351 1.00 100.80 ? 167 SER F CB 1 +ATOM 10795 O OG . SER F 1 167 ? 70.780 -9.989 56.723 1.00 136.58 ? 167 SER F OG 1 +ATOM 10796 N N . THR F 1 168 ? 70.466 -11.435 52.359 1.00 44.61 ? 168 THR F N 1 +ATOM 10797 C CA . THR F 1 168 ? 70.990 -11.537 50.990 1.00 55.60 ? 168 THR F CA 1 +ATOM 10798 C C . THR F 1 168 ? 70.303 -12.546 50.121 1.00 60.23 ? 168 THR F C 1 +ATOM 10799 O O . THR F 1 168 ? 70.096 -12.344 48.911 1.00 85.53 ? 168 THR F O 1 +ATOM 10800 C CB . THR F 1 168 ? 72.466 -11.949 50.958 1.00 63.55 ? 168 THR F CB 1 +ATOM 10801 O OG1 . THR F 1 168 ? 72.656 -13.102 51.772 1.00 67.91 ? 168 THR F OG1 1 +ATOM 10802 C CG2 . THR F 1 168 ? 73.373 -10.806 51.462 1.00 72.34 ? 168 THR F CG2 1 +ATOM 10803 N N . GLY F 1 169 ? 69.864 -13.622 50.734 1.00 70.31 ? 169 GLY F N 1 +ATOM 10804 C CA . GLY F 1 169 ? 69.184 -14.645 49.964 1.00 80.61 ? 169 GLY F CA 1 +ATOM 10805 C C . GLY F 1 169 ? 70.184 -15.701 49.633 1.00 103.95 ? 169 GLY F C 1 +ATOM 10806 O O . GLY F 1 169 ? 69.811 -16.773 49.142 1.00 157.54 ? 169 GLY F O 1 +ATOM 10807 N N . GLU F 1 170 ? 71.470 -15.407 49.857 1.00 106.20 ? 170 GLU F N 1 +ATOM 10808 C CA . GLU F 1 170 ? 72.508 -16.454 49.782 1.00 134.19 ? 170 GLU F CA 1 +ATOM 10809 C C . GLU F 1 170 ? 72.091 -17.619 50.693 1.00 96.58 ? 170 GLU F C 1 +ATOM 10810 O O . GLU F 1 170 ? 71.750 -17.408 51.837 1.00 90.60 ? 170 GLU F O 1 +ATOM 10811 C CB . GLU F 1 170 ? 73.889 -15.928 50.218 1.00 139.60 ? 170 GLU F CB 1 +ATOM 10812 C CG . GLU F 1 170 ? 74.590 -15.065 49.178 1.00 134.30 ? 170 GLU F CG 1 +ATOM 10813 C CD . GLU F 1 170 ? 75.390 -13.916 49.770 1.00 159.44 ? 170 GLU F CD 1 +ATOM 10814 O OE1 . GLU F 1 170 ? 75.240 -13.629 50.980 1.00 213.61 ? 170 GLU F OE1 1 +ATOM 10815 O OE2 . GLU F 1 170 ? 76.118 -13.240 49.013 1.00 168.44 ? 170 GLU F OE2 1 +ATOM 10816 N N . ILE F 1 171 ? 72.042 -18.822 50.154 1.00 56.42 ? 171 ILE F N 1 +ATOM 10817 C CA . ILE F 1 171 ? 71.990 -19.953 50.988 1.00 52.61 ? 171 ILE F CA 1 +ATOM 10818 C C . ILE F 1 171 ? 73.331 -20.085 51.679 1.00 70.50 ? 171 ILE F C 1 +ATOM 10819 O O . ILE F 1 171 ? 74.386 -20.130 51.022 1.00 127.39 ? 171 ILE F O 1 +ATOM 10820 C CB . ILE F 1 171 ? 71.679 -21.179 50.166 1.00 63.30 ? 171 ILE F CB 1 +ATOM 10821 C CG1 . ILE F 1 171 ? 70.220 -21.113 49.684 1.00 70.83 ? 171 ILE F CG1 1 +ATOM 10822 C CG2 . ILE F 1 171 ? 71.935 -22.437 50.985 1.00 69.05 ? 171 ILE F CG2 1 +ATOM 10823 C CD1 . ILE F 1 171 ? 69.916 -22.082 48.566 1.00 81.84 ? 171 ILE F CD1 1 +ATOM 10824 N N . LEU F 1 172 ? 73.323 -20.168 53.006 1.00 91.38 ? 172 LEU F N 1 +ATOM 10825 C CA . LEU F 1 172 ? 74.577 -20.253 53.777 1.00 103.30 ? 172 LEU F CA 1 +ATOM 10826 C C . LEU F 1 172 ? 75.016 -21.701 54.094 1.00 118.77 ? 172 LEU F C 1 +ATOM 10827 O O . LEU F 1 172 ? 76.178 -21.988 54.479 1.00 77.74 ? 172 LEU F O 1 +ATOM 10828 C CB . LEU F 1 172 ? 74.471 -19.471 55.082 1.00 86.71 ? 172 LEU F CB 1 +ATOM 10829 C CG . LEU F 1 172 ? 74.417 -17.934 54.868 1.00 108.90 ? 172 LEU F CG 1 +ATOM 10830 C CD1 . LEU F 1 172 ? 74.456 -17.075 56.150 1.00 115.55 ? 172 LEU F CD1 1 +ATOM 10831 C CD2 . LEU F 1 172 ? 75.407 -17.409 53.827 1.00 84.64 ? 172 LEU F CD2 1 +ATOM 10832 N N . SER F 1 173 ? 74.087 -22.625 53.889 1.00 144.40 ? 173 SER F N 1 +ATOM 10833 C CA . SER F 1 173 ? 74.390 -24.043 54.072 1.00 143.48 ? 173 SER F CA 1 +ATOM 10834 C C . SER F 1 173 ? 73.275 -24.920 53.527 1.00 119.75 ? 173 SER F C 1 +ATOM 10835 O O . SER F 1 173 ? 72.107 -24.691 53.830 1.00 178.02 ? 173 SER F O 1 +ATOM 10836 C CB . SER F 1 173 ? 74.571 -24.330 55.558 1.00 152.01 ? 173 SER F CB 1 +ATOM 10837 O OG . SER F 1 173 ? 74.507 -25.719 55.811 1.00 116.23 ? 173 SER F OG 1 +ATOM 10838 N N . SER F 1 174 ? 73.631 -25.938 52.753 1.00 80.57 ? 174 SER F N 1 +ATOM 10839 C CA . SER F 1 174 ? 72.677 -26.979 52.418 1.00 98.73 ? 174 SER F CA 1 +ATOM 10840 C C . SER F 1 174 ? 73.203 -28.317 52.941 1.00 104.75 ? 174 SER F C 1 +ATOM 10841 O O . SER F 1 174 ? 74.378 -28.632 52.751 1.00 127.78 ? 174 SER F O 1 +ATOM 10842 C CB . SER F 1 174 ? 72.445 -27.026 50.897 1.00 93.07 ? 174 SER F CB 1 +ATOM 10843 O OG . SER F 1 174 ? 71.338 -27.867 50.546 1.00 109.40 ? 174 SER F OG 1 +ATOM 10844 N N . VAL F 1 175 ? 72.320 -29.126 53.533 1.00 71.63 ? 175 VAL F N 1 +ATOM 10845 C CA . VAL F 1 175 ? 72.684 -30.466 53.962 1.00 58.10 ? 175 VAL F CA 1 +ATOM 10846 C C . VAL F 1 175 ? 71.634 -31.516 53.582 1.00 83.85 ? 175 VAL F C 1 +ATOM 10847 O O . VAL F 1 175 ? 70.438 -31.255 53.608 1.00 110.19 ? 175 VAL F O 1 +ATOM 10848 C CB . VAL F 1 175 ? 72.890 -30.504 55.479 1.00 64.06 ? 175 VAL F CB 1 +ATOM 10849 C CG1 . VAL F 1 175 ? 74.056 -29.601 55.868 1.00 93.53 ? 175 VAL F CG1 1 +ATOM 10850 C CG2 . VAL F 1 175 ? 71.644 -30.073 56.221 1.00 53.06 ? 175 VAL F CG2 1 +ATOM 10851 N N . ASN F 1 176 ? 72.095 -32.741 53.311 1.00 116.87 ? 176 ASN F N 1 +ATOM 10852 C CA . ASN F 1 176 ? 71.241 -33.831 52.790 1.00 99.85 ? 176 ASN F CA 1 +ATOM 10853 C C . ASN F 1 176 ? 71.333 -35.129 53.597 1.00 79.39 ? 176 ASN F C 1 +ATOM 10854 O O . ASN F 1 176 ? 72.232 -35.922 53.356 1.00 92.81 ? 176 ASN F O 1 +ATOM 10855 C CB . ASN F 1 176 ? 71.660 -34.106 51.332 1.00 112.15 ? 176 ASN F CB 1 +ATOM 10856 C CG . ASN F 1 176 ? 70.784 -33.390 50.300 1.00 127.34 ? 176 ASN F CG 1 +ATOM 10857 O OD1 . ASN F 1 176 ? 70.799 -33.689 49.065 1.00 77.64 ? 176 ASN F OD1 1 +ATOM 10858 N ND2 . ASN F 1 176 ? 69.973 -32.473 50.804 1.00 136.24 ? 176 ASN F ND2 1 +ATOM 10859 N N . THR F 1 177 ? 70.436 -35.330 54.561 1.00 70.13 ? 177 THR F N 1 +ATOM 10860 C CA . THR F 1 177 ? 70.526 -36.480 55.471 1.00 100.64 ? 177 THR F CA 1 +ATOM 10861 C C . THR F 1 177 ? 69.575 -37.595 55.040 1.00 88.16 ? 177 THR F C 1 +ATOM 10862 O O . THR F 1 177 ? 68.685 -37.357 54.257 1.00 77.64 ? 177 THR F O 1 +ATOM 10863 C CB . THR F 1 177 ? 70.210 -36.116 56.937 1.00 111.02 ? 177 THR F CB 1 +ATOM 10864 O OG1 . THR F 1 177 ? 68.826 -35.800 57.053 1.00 116.31 ? 177 THR F OG1 1 +ATOM 10865 C CG2 . THR F 1 177 ? 71.050 -34.926 57.424 1.00 111.14 ? 177 THR F CG2 1 +ATOM 10866 N N . SER F 1 178 ? 69.838 -38.820 55.503 1.00 141.36 ? 178 SER F N 1 +ATOM 10867 C CA . SER F 1 178 ? 69.112 -40.021 55.057 1.00 161.31 ? 178 SER F CA 1 +ATOM 10868 C C . SER F 1 178 ? 69.018 -41.050 56.174 1.00 134.56 ? 178 SER F C 1 +ATOM 10869 O O . SER F 1 178 ? 69.870 -41.118 57.044 1.00 149.84 ? 178 SER F O 1 +ATOM 10870 C CB . SER F 1 178 ? 69.776 -40.683 53.825 1.00 159.54 ? 178 SER F CB 1 +ATOM 10871 O OG . SER F 1 178 ? 69.244 -41.990 53.584 1.00 95.31 ? 178 SER F OG 1 +ATOM 10872 N N . LYS F 1 179 ? 68.006 -41.898 56.097 1.00 109.09 ? 179 LYS F N 1 +ATOM 10873 C CA . LYS F 1 179 ? 67.718 -42.799 57.186 1.00 125.97 ? 179 LYS F CA 1 +ATOM 10874 C C . LYS F 1 179 ? 66.890 -43.978 56.690 1.00 127.51 ? 179 LYS F C 1 +ATOM 10875 O O . LYS F 1 179 ? 66.033 -43.843 55.808 1.00 158.74 ? 179 LYS F O 1 +ATOM 10876 C CB . LYS F 1 179 ? 66.986 -42.045 58.304 1.00 138.91 ? 179 LYS F CB 1 +ATOM 10877 C CG . LYS F 1 179 ? 67.349 -42.490 59.706 1.00 148.24 ? 179 LYS F CG 1 +ATOM 10878 C CD . LYS F 1 179 ? 66.372 -43.540 60.202 1.00 150.26 ? 179 LYS F CD 1 +ATOM 10879 C CE . LYS F 1 179 ? 66.831 -44.111 61.526 1.00 169.20 ? 179 LYS F CE 1 +ATOM 10880 N NZ . LYS F 1 179 ? 66.076 -45.338 61.881 1.00 191.49 ? 179 LYS F NZ 1 +ATOM 10881 N N . THR F 1 180 ? 67.146 -45.134 57.279 1.00 139.72 ? 180 THR F N 1 +ATOM 10882 C CA . THR F 1 180 ? 66.525 -46.365 56.842 1.00 164.31 ? 180 THR F CA 1 +ATOM 10883 C C . THR F 1 180 ? 65.471 -46.841 57.852 1.00 148.40 ? 180 THR F C 1 +ATOM 10884 O O . THR F 1 180 ? 65.721 -46.903 59.058 1.00 142.26 ? 180 THR F O 1 +ATOM 10885 C CB . THR F 1 180 ? 67.572 -47.479 56.577 1.00 198.92 ? 180 THR F CB 1 +ATOM 10886 O OG1 . THR F 1 180 ? 66.949 -48.767 56.708 1.00 239.99 ? 180 THR F OG1 1 +ATOM 10887 C CG2 . THR F 1 180 ? 68.746 -47.378 57.532 1.00 193.42 ? 180 THR F CG2 1 +ATOM 10888 N N . ILE F 1 181 ? 64.299 -47.205 57.336 1.00 159.11 ? 181 ILE F N 1 +ATOM 10889 C CA . ILE F 1 181 ? 63.211 -47.745 58.163 1.00 172.30 ? 181 ILE F CA 1 +ATOM 10890 C C . ILE F 1 181 ? 63.148 -49.294 58.108 1.00 198.47 ? 181 ILE F C 1 +ATOM 10891 O O . ILE F 1 181 ? 62.924 -49.845 57.024 1.00 152.15 ? 181 ILE F O 1 +ATOM 10892 C CB . ILE F 1 181 ? 61.848 -47.139 57.730 1.00 149.78 ? 181 ILE F CB 1 +ATOM 10893 C CG1 . ILE F 1 181 ? 61.936 -45.612 57.686 1.00 125.66 ? 181 ILE F CG1 1 +ATOM 10894 C CG2 . ILE F 1 181 ? 60.730 -47.551 58.674 1.00 136.04 ? 181 ILE F CG2 1 +ATOM 10895 C CD1 . ILE F 1 181 ? 61.671 -45.036 56.320 1.00 144.92 ? 181 ILE F CD1 1 +ATOM 10896 N N . LEU F 1 182 ? 63.351 -49.959 59.267 1.00 212.98 ? 182 LEU F N 1 +ATOM 10897 C CA . LEU F 1 182 ? 63.360 -51.462 59.393 1.00 189.18 ? 182 LEU F CA 1 +ATOM 10898 C C . LEU F 1 182 ? 61.976 -52.024 59.669 1.00 134.52 ? 182 LEU F C 1 +ATOM 10899 O O . LEU F 1 182 ? 61.274 -51.568 60.575 1.00 75.79 ? 182 LEU F O 1 +ATOM 10900 C CB . LEU F 1 182 ? 64.240 -52.035 60.591 1.00 207.96 ? 182 LEU F CB 1 +ATOM 10901 C CG . LEU F 1 182 ? 65.744 -52.419 60.543 1.00 227.44 ? 182 LEU F CG 1 +ATOM 10902 C CD1 . LEU F 1 182 ? 66.625 -51.277 60.041 1.00 204.86 ? 182 LEU F CD1 1 +ATOM 10903 C CD2 . LEU F 1 182 ? 66.215 -52.895 61.926 1.00 221.03 ? 182 LEU F CD2 1 +ATOM 10904 N N . SER F 1 183 ? 61.695 -53.139 59.011 1.00 138.33 ? 183 SER F N 1 +ATOM 10905 C CA . SER F 1 183 ? 60.519 -53.945 59.315 1.00 135.61 ? 183 SER F CA 1 +ATOM 10906 C C . SER F 1 183 ? 60.857 -55.441 59.246 1.00 179.32 ? 183 SER F C 1 +ATOM 10907 O O . SER F 1 183 ? 61.663 -55.864 58.409 1.00 149.39 ? 183 SER F O 1 +ATOM 10908 C CB . SER F 1 183 ? 59.429 -53.635 58.313 1.00 118.78 ? 183 SER F CB 1 +ATOM 10909 O OG . SER F 1 183 ? 59.417 -52.264 57.983 1.00 131.07 ? 183 SER F OG 1 +ATOM 10910 N N . TYR F 1 184 ? 60.271 -56.231 60.151 1.00 185.62 ? 184 TYR F N 1 +ATOM 10911 C CA . TYR F 1 184 ? 60.470 -57.681 60.137 1.00 141.33 ? 184 TYR F CA 1 +ATOM 10912 C C . TYR F 1 184 ? 59.287 -58.491 60.710 1.00 133.05 ? 184 TYR F C 1 +ATOM 10913 O O . TYR F 1 184 ? 58.501 -58.012 61.539 1.00 82.47 ? 184 TYR F O 1 +ATOM 10914 C CB . TYR F 1 184 ? 61.781 -58.056 60.830 1.00 107.16 ? 184 TYR F CB 1 +ATOM 10915 C CG . TYR F 1 184 ? 61.847 -57.620 62.278 1.00 133.24 ? 184 TYR F CG 1 +ATOM 10916 C CD1 . TYR F 1 184 ? 61.273 -58.393 63.298 1.00 144.77 ? 184 TYR F CD1 1 +ATOM 10917 C CD2 . TYR F 1 184 ? 62.507 -56.457 62.640 1.00 156.64 ? 184 TYR F CD2 1 +ATOM 10918 C CE1 . TYR F 1 184 ? 61.340 -58.005 64.628 1.00 119.39 ? 184 TYR F CE1 1 +ATOM 10919 C CE2 . TYR F 1 184 ? 62.576 -56.057 63.964 1.00 166.83 ? 184 TYR F CE2 1 +ATOM 10920 C CZ . TYR F 1 184 ? 62.001 -56.842 64.953 1.00 142.35 ? 184 TYR F CZ 1 +ATOM 10921 O OH . TYR F 1 184 ? 62.059 -56.424 66.260 1.00 132.52 ? 184 TYR F OH 1 +ATOM 10922 N N . GLU F 1 185 ? 59.187 -59.727 60.226 1.00 145.66 ? 185 GLU F N 1 +ATOM 10923 C CA . GLU F 1 185 ? 58.132 -60.660 60.598 1.00 152.46 ? 185 GLU F CA 1 +ATOM 10924 C C . GLU F 1 185 ? 58.725 -62.019 60.941 1.00 179.76 ? 185 GLU F C 1 +ATOM 10925 O O . GLU F 1 185 ? 59.222 -62.729 60.071 1.00 139.28 ? 185 GLU F O 1 +ATOM 10926 C CB . GLU F 1 185 ? 57.108 -60.852 59.481 1.00 160.35 ? 185 GLU F CB 1 +ATOM 10927 C CG . GLU F 1 185 ? 56.692 -59.601 58.743 1.00 178.50 ? 185 GLU F CG 1 +ATOM 10928 C CD . GLU F 1 185 ? 55.533 -59.876 57.800 1.00 205.42 ? 185 GLU F CD 1 +ATOM 10929 O OE1 . GLU F 1 185 ? 55.090 -61.051 57.713 1.00 222.30 ? 185 GLU F OE1 1 +ATOM 10930 O OE2 . GLU F 1 185 ? 55.028 -58.912 57.188 1.00 203.61 ? 185 GLU F OE2 1 +ATOM 10931 N N . VAL F 1 186 ? 58.614 -62.394 62.210 1.00 199.38 ? 186 VAL F N 1 +ATOM 10932 C CA . VAL F 1 186 ? 59.043 -63.704 62.688 1.00 190.15 ? 186 VAL F CA 1 +ATOM 10933 C C . VAL F 1 186 ? 57.837 -64.631 62.895 1.00 188.16 ? 186 VAL F C 1 +ATOM 10934 O O . VAL F 1 186 ? 56.795 -64.188 63.378 1.00 150.57 ? 186 VAL F O 1 +ATOM 10935 C CB . VAL F 1 186 ? 59.813 -63.571 64.009 1.00 169.13 ? 186 VAL F CB 1 +ATOM 10936 C CG1 . VAL F 1 186 ? 60.440 -64.900 64.392 1.00 182.93 ? 186 VAL F CG1 1 +ATOM 10937 C CG2 . VAL F 1 186 ? 60.880 -62.495 63.895 1.00 173.61 ? 186 VAL F CG2 1 +ATOM 10938 N N . GLN F 1 187 ? 57.977 -65.898 62.499 1.00 162.84 ? 187 GLN F N 1 +ATOM 10939 C CA . GLN F 1 187 ? 56.865 -66.839 62.545 1.00 146.50 ? 187 GLN F CA 1 +ATOM 10940 C C . GLN F 1 187 ? 57.351 -68.250 62.792 1.00 155.61 ? 187 GLN F C 1 +ATOM 10941 O O . GLN F 1 187 ? 58.325 -68.690 62.188 1.00 123.55 ? 187 GLN F O 1 +ATOM 10942 C CB . GLN F 1 187 ? 56.098 -66.807 61.215 1.00 160.16 ? 187 GLN F CB 1 +ATOM 10943 C CG . GLN F 1 187 ? 55.030 -65.736 61.098 1.00 179.89 ? 187 GLN F CG 1 +ATOM 10944 C CD . GLN F 1 187 ? 54.679 -65.435 59.651 1.00 191.52 ? 187 GLN F CD 1 +ATOM 10945 O OE1 . GLN F 1 187 ? 54.606 -66.345 58.822 1.00 170.43 ? 187 GLN F OE1 1 +ATOM 10946 N NE2 . GLN F 1 187 ? 54.458 -64.150 59.336 1.00 187.98 ? 187 GLN F NE2 1 +ATOM 10947 N N . ALA F 1 188 ? 56.619 -68.982 63.626 1.00 183.99 ? 188 ALA F N 1 +ATOM 10948 C CA . ALA F 1 188 ? 56.906 -70.397 63.855 1.00 187.51 ? 188 ALA F CA 1 +ATOM 10949 C C . ALA F 1 188 ? 55.613 -71.207 63.987 1.00 190.64 ? 188 ALA F C 1 +ATOM 10950 O O . ALA F 1 188 ? 54.647 -70.735 64.564 1.00 144.21 ? 188 ALA F O 1 +ATOM 10951 C CB . ALA F 1 188 ? 57.772 -70.553 65.092 1.00 156.78 ? 188 ALA F CB 1 +ATOM 10952 N N . GLY F 1 189 ? 55.595 -72.411 63.418 1.00 187.42 ? 189 GLY F N 1 +ATOM 10953 C CA . GLY F 1 189 ? 54.413 -73.267 63.460 1.00 173.97 ? 189 GLY F CA 1 +ATOM 10954 C C . GLY F 1 189 ? 54.740 -74.749 63.547 1.00 185.61 ? 189 GLY F C 1 +ATOM 10955 O O . GLY F 1 189 ? 55.673 -75.230 62.904 1.00 135.66 ? 189 GLY F O 1 +ATOM 10956 N N . VAL F 1 190 ? 53.987 -75.469 64.375 1.00 219.89 ? 190 VAL F N 1 +ATOM 10957 C CA . VAL F 1 190 ? 54.155 -76.917 64.528 1.00 226.53 ? 190 VAL F CA 1 +ATOM 10958 C C . VAL F 1 190 ? 52.898 -77.642 64.041 1.00 228.08 ? 190 VAL F C 1 +ATOM 10959 O O . VAL F 1 190 ? 51.780 -77.214 64.323 1.00 189.60 ? 190 VAL F O 1 +ATOM 10960 C CB . VAL F 1 190 ? 54.431 -77.304 65.995 1.00 211.64 ? 190 VAL F CB 1 +ATOM 10961 C CG1 . VAL F 1 190 ? 54.852 -78.761 66.085 1.00 193.96 ? 190 VAL F CG1 1 +ATOM 10962 C CG2 . VAL F 1 190 ? 55.494 -76.393 66.609 1.00 209.81 ? 190 VAL F CG2 1 +ATOM 10963 N N . PHE F 1 191 ? 53.086 -78.711 63.272 1.00 243.45 ? 191 PHE F N 1 +ATOM 10964 C CA . PHE F 1 191 ? 51.979 -79.352 62.562 1.00 247.87 ? 191 PHE F CA 1 +ATOM 10965 C C . PHE F 1 191 ? 52.055 -80.860 62.755 1.00 220.91 ? 191 PHE F C 1 +ATOM 10966 O O . PHE F 1 191 ? 53.109 -81.458 62.520 1.00 259.78 ? 191 PHE F O 1 +ATOM 10967 C CB . PHE F 1 191 ? 52.009 -78.974 61.062 1.00 245.17 ? 191 PHE F CB 1 +ATOM 10968 C CG . PHE F 1 191 ? 50.687 -79.149 60.357 1.00 248.06 ? 191 PHE F CG 1 +ATOM 10969 C CD1 . PHE F 1 191 ? 50.198 -80.413 60.068 1.00 226.17 ? 191 PHE F CD1 1 +ATOM 10970 C CD2 . PHE F 1 191 ? 49.938 -78.044 59.966 1.00 255.05 ? 191 PHE F CD2 1 +ATOM 10971 C CE1 . PHE F 1 191 ? 48.982 -80.577 59.419 1.00 195.13 ? 191 PHE F CE1 1 +ATOM 10972 C CE2 . PHE F 1 191 ? 48.718 -78.202 59.325 1.00 229.61 ? 191 PHE F CE2 1 +ATOM 10973 C CZ . PHE F 1 191 ? 48.239 -79.471 59.050 1.00 193.31 ? 191 PHE F CZ 1 +ATOM 10974 N N . LEU F 1 200 ? 47.122 -82.058 65.275 1.00 253.01 ? 200 LEU F N 1 +ATOM 10975 C CA . LEU F 1 200 ? 47.789 -80.991 66.022 1.00 256.46 ? 200 LEU F CA 1 +ATOM 10976 C C . LEU F 1 200 ? 48.375 -79.931 65.095 1.00 248.13 ? 200 LEU F C 1 +ATOM 10977 O O . LEU F 1 200 ? 49.314 -80.207 64.344 1.00 171.06 ? 200 LEU F O 1 +ATOM 10978 C CB . LEU F 1 200 ? 48.915 -81.561 66.889 1.00 233.72 ? 200 LEU F CB 1 +ATOM 10979 C CG . LEU F 1 200 ? 49.810 -80.496 67.549 1.00 197.89 ? 200 LEU F CG 1 +ATOM 10980 C CD1 . LEU F 1 200 ? 49.414 -80.313 69.010 1.00 174.17 ? 200 LEU F CD1 1 +ATOM 10981 C CD2 . LEU F 1 200 ? 51.300 -80.802 67.408 1.00 173.27 ? 200 LEU F CD2 1 +ATOM 10982 N N . GLU F 1 201 ? 47.829 -78.718 65.179 1.00 248.64 ? 201 GLU F N 1 +ATOM 10983 C CA . GLU F 1 201 ? 48.508 -77.528 64.677 1.00 217.17 ? 201 GLU F CA 1 +ATOM 10984 C C . GLU F 1 201 ? 48.729 -76.520 65.800 1.00 199.07 ? 201 GLU F C 1 +ATOM 10985 O O . GLU F 1 201 ? 47.929 -76.434 66.730 1.00 128.15 ? 201 GLU F O 1 +ATOM 10986 C CB . GLU F 1 201 ? 47.703 -76.873 63.556 1.00 198.80 ? 201 GLU F CB 1 +ATOM 10987 C CG . GLU F 1 201 ? 48.546 -75.951 62.688 1.00 193.01 ? 201 GLU F CG 1 +ATOM 10988 C CD . GLU F 1 201 ? 47.758 -75.297 61.564 1.00 185.78 ? 201 GLU F CD 1 +ATOM 10989 O OE1 . GLU F 1 201 ? 47.059 -76.016 60.818 1.00 204.30 ? 201 GLU F OE1 1 +ATOM 10990 O OE2 . GLU F 1 201 ? 47.866 -74.063 61.406 1.00 154.83 ? 201 GLU F OE2 1 +ATOM 10991 N N . GLY F 1 202 ? 49.827 -75.773 65.716 1.00 192.52 ? 202 GLY F N 1 +ATOM 10992 C CA . GLY F 1 202 ? 50.099 -74.680 66.645 1.00 168.66 ? 202 GLY F CA 1 +ATOM 10993 C C . GLY F 1 202 ? 51.002 -73.636 66.011 1.00 146.42 ? 202 GLY F C 1 +ATOM 10994 O O . GLY F 1 202 ? 52.080 -73.958 65.520 1.00 105.85 ? 202 GLY F O 1 +ATOM 10995 N N . GLU F 1 203 ? 50.575 -72.378 66.044 1.00 146.39 ? 203 GLU F N 1 +ATOM 10996 C CA . GLU F 1 203 ? 51.326 -71.306 65.403 1.00 156.47 ? 203 GLU F CA 1 +ATOM 10997 C C . GLU F 1 203 ? 51.550 -70.087 66.303 1.00 160.61 ? 203 GLU F C 1 +ATOM 10998 O O . GLU F 1 203 ? 50.633 -69.619 66.986 1.00 118.83 ? 203 GLU F O 1 +ATOM 10999 C CB . GLU F 1 203 ? 50.616 -70.877 64.122 1.00 193.19 ? 203 GLU F CB 1 +ATOM 11000 C CG . GLU F 1 203 ? 50.613 -71.960 63.046 1.00 196.35 ? 203 GLU F CG 1 +ATOM 11001 C CD . GLU F 1 203 ? 50.016 -71.519 61.713 1.00 219.08 ? 203 GLU F CD 1 +ATOM 11002 O OE1 . GLU F 1 203 ? 49.428 -70.409 61.651 1.00 277.11 ? 203 GLU F OE1 1 +ATOM 11003 O OE2 . GLU F 1 203 ? 50.092 -72.311 60.736 1.00 162.68 ? 203 GLU F OE2 1 +ATOM 11004 N N . VAL F 1 204 ? 52.769 -69.558 66.254 1.00 172.99 ? 204 VAL F N 1 +ATOM 11005 C CA . VAL F 1 204 ? 53.124 -68.283 66.875 1.00 187.18 ? 204 VAL F CA 1 +ATOM 11006 C C . VAL F 1 204 ? 53.700 -67.336 65.816 1.00 212.90 ? 204 VAL F C 1 +ATOM 11007 O O . VAL F 1 204 ? 54.502 -67.745 64.976 1.00 196.02 ? 204 VAL F O 1 +ATOM 11008 C CB . VAL F 1 204 ? 54.139 -68.493 68.019 1.00 140.05 ? 204 VAL F CB 1 +ATOM 11009 C CG1 . VAL F 1 204 ? 54.803 -67.184 68.439 1.00 133.96 ? 204 VAL F CG1 1 +ATOM 11010 C CG2 . VAL F 1 204 ? 53.444 -69.142 69.209 1.00 123.60 ? 204 VAL F CG2 1 +ATOM 11011 N N . GLY F 1 205 ? 53.273 -66.072 65.861 1.00 206.84 ? 205 GLY F N 1 +ATOM 11012 C CA . GLY F 1 205 ? 53.790 -65.047 64.964 1.00 177.24 ? 205 GLY F CA 1 +ATOM 11013 C C . GLY F 1 205 ? 54.063 -63.723 65.667 1.00 180.83 ? 205 GLY F C 1 +ATOM 11014 O O . GLY F 1 205 ? 53.416 -63.397 66.662 1.00 140.46 ? 205 GLY F O 1 +ATOM 11015 N N . TYR F 1 206 ? 55.007 -62.948 65.130 1.00 209.85 ? 206 TYR F N 1 +ATOM 11016 C CA . TYR F 1 206 ? 55.288 -61.579 65.599 1.00 226.16 ? 206 TYR F CA 1 +ATOM 11017 C C . TYR F 1 206 ? 55.770 -60.697 64.437 1.00 215.98 ? 206 TYR F C 1 +ATOM 11018 O O . TYR F 1 206 ? 56.530 -61.160 63.600 1.00 193.09 ? 206 TYR F O 1 +ATOM 11019 C CB . TYR F 1 206 ? 56.355 -61.606 66.703 1.00 219.55 ? 206 TYR F CB 1 +ATOM 11020 C CG . TYR F 1 206 ? 56.766 -60.242 67.225 1.00 217.71 ? 206 TYR F CG 1 +ATOM 11021 C CD1 . TYR F 1 206 ? 55.949 -59.533 68.110 1.00 182.29 ? 206 TYR F CD1 1 +ATOM 11022 C CD2 . TYR F 1 206 ? 57.982 -59.672 66.844 1.00 198.81 ? 206 TYR F CD2 1 +ATOM 11023 C CE1 . TYR F 1 206 ? 56.325 -58.289 68.585 1.00 169.36 ? 206 TYR F CE1 1 +ATOM 11024 C CE2 . TYR F 1 206 ? 58.366 -58.430 67.308 1.00 181.04 ? 206 TYR F CE2 1 +ATOM 11025 C CZ . TYR F 1 206 ? 57.540 -57.740 68.176 1.00 192.39 ? 206 TYR F CZ 1 +ATOM 11026 O OH . TYR F 1 206 ? 57.918 -56.477 68.585 1.00 203.60 ? 206 TYR F OH 1 +ATOM 11027 N N . THR F 1 207 ? 55.351 -59.429 64.408 1.00 169.11 ? 207 THR F N 1 +ATOM 11028 C CA . THR F 1 207 ? 55.804 -58.480 63.376 1.00 143.62 ? 207 THR F CA 1 +ATOM 11029 C C . THR F 1 207 ? 56.108 -57.086 63.945 1.00 136.06 ? 207 THR F C 1 +ATOM 11030 O O . THR F 1 207 ? 55.384 -56.593 64.819 1.00 107.22 ? 207 THR F O 1 +ATOM 11031 C CB . THR F 1 207 ? 54.747 -58.306 62.285 1.00 149.34 ? 207 THR F CB 1 +ATOM 11032 O OG1 . THR F 1 207 ? 53.551 -57.770 62.864 1.00 115.87 ? 207 THR F OG1 1 +ATOM 11033 C CG2 . THR F 1 207 ? 54.421 -59.633 61.635 1.00 162.76 ? 207 THR F CG2 1 +ATOM 11034 N N . SER F 1 208 ? 57.210 -56.474 63.495 1.00 147.46 ? 208 SER F N 1 +ATOM 11035 C CA . SER F 1 208 ? 57.615 -55.153 64.022 1.00 123.92 ? 208 SER F CA 1 +ATOM 11036 C C . SER F 1 208 ? 58.065 -54.189 62.924 1.00 147.82 ? 208 SER F C 1 +ATOM 11037 O O . SER F 1 208 ? 58.957 -54.511 62.122 1.00 132.02 ? 208 SER F O 1 +ATOM 11038 C CB . SER F 1 208 ? 58.732 -55.289 65.060 1.00 115.34 ? 208 SER F CB 1 +ATOM 11039 O OG . SER F 1 208 ? 59.203 -54.017 65.476 1.00 78.93 ? 208 SER F OG 1 +ATOM 11040 N N . ASN F 1 209 ? 57.464 -53.002 62.924 1.00 149.09 ? 209 ASN F N 1 +ATOM 11041 C CA . ASN F 1 209 ? 57.841 -51.929 62.009 1.00 147.66 ? 209 ASN F CA 1 +ATOM 11042 C C . ASN F 1 209 ? 58.417 -50.750 62.762 1.00 156.52 ? 209 ASN F C 1 +ATOM 11043 O O . ASN F 1 209 ? 57.896 -50.370 63.806 1.00 103.21 ? 209 ASN F O 1 +ATOM 11044 C CB . ASN F 1 209 ? 56.624 -51.436 61.252 1.00 132.82 ? 209 ASN F CB 1 +ATOM 11045 C CG . ASN F 1 209 ? 56.120 -52.444 60.263 1.00 145.32 ? 209 ASN F CG 1 +ATOM 11046 O OD1 . ASN F 1 209 ? 56.616 -52.536 59.142 1.00 172.60 ? 209 ASN F OD1 1 +ATOM 11047 N ND2 . ASN F 1 209 ? 55.096 -53.179 60.653 1.00 167.37 ? 209 ASN F ND2 1 +ATOM 11048 N N . GLU F 1 210 ? 59.494 -50.168 62.227 1.00 172.85 ? 210 GLU F N 1 +ATOM 11049 C CA . GLU F 1 210 ? 59.983 -48.886 62.730 1.00 134.35 ? 210 GLU F CA 1 +ATOM 11050 C C . GLU F 1 210 ? 58.944 -47.844 62.373 1.00 122.97 ? 210 GLU F C 1 +ATOM 11051 O O . GLU F 1 210 ? 58.341 -47.898 61.298 1.00 132.20 ? 210 GLU F O 1 +ATOM 11052 C CB . GLU F 1 210 ? 61.331 -48.521 62.100 1.00 129.56 ? 210 GLU F CB 1 +ATOM 11053 C CG . GLU F 1 210 ? 62.357 -47.952 63.067 1.00 132.33 ? 210 GLU F CG 1 +ATOM 11054 C CD . GLU F 1 210 ? 63.781 -47.990 62.505 1.00 158.38 ? 210 GLU F CD 1 +ATOM 11055 O OE1 . GLU F 1 210 ? 64.108 -48.845 61.629 1.00 130.06 ? 210 GLU F OE1 1 +ATOM 11056 O OE2 . GLU F 1 210 ? 64.591 -47.129 62.921 1.00 209.63 ? 210 GLU F OE2 1 +ATOM 11057 N N . PRO F 1 211 ? 58.717 -46.894 63.271 1.00 123.28 ? 211 PRO F N 1 +ATOM 11058 C CA . PRO F 1 211 ? 57.854 -45.789 62.912 1.00 144.34 ? 211 PRO F CA 1 +ATOM 11059 C C . PRO F 1 211 ? 58.555 -44.827 61.930 1.00 161.03 ? 211 PRO F C 1 +ATOM 11060 O O . PRO F 1 211 ? 59.662 -44.342 62.214 1.00 121.23 ? 211 PRO F O 1 +ATOM 11061 C CB . PRO F 1 211 ? 57.580 -45.108 64.255 1.00 155.20 ? 211 PRO F CB 1 +ATOM 11062 C CG . PRO F 1 211 ? 57.927 -46.110 65.293 1.00 156.92 ? 211 PRO F CG 1 +ATOM 11063 C CD . PRO F 1 211 ? 59.056 -46.891 64.696 1.00 146.23 ? 211 PRO F CD 1 +ATOM 11064 N N . VAL F 1 212 ? 57.906 -44.566 60.787 1.00 118.91 ? 212 VAL F N 1 +ATOM 11065 C CA . VAL F 1 212 ? 58.429 -43.640 59.764 1.00 76.80 ? 212 VAL F CA 1 +ATOM 11066 C C . VAL F 1 212 ? 58.475 -42.225 60.329 1.00 60.85 ? 212 VAL F C 1 +ATOM 11067 O O . VAL F 1 212 ? 59.456 -41.502 60.187 1.00 38.44 ? 212 VAL F O 1 +ATOM 11068 C CB . VAL F 1 212 ? 57.532 -43.614 58.529 1.00 104.68 ? 212 VAL F CB 1 +ATOM 11069 C CG1 . VAL F 1 212 ? 58.157 -42.749 57.445 1.00 102.47 ? 212 VAL F CG1 1 +ATOM 11070 C CG2 . VAL F 1 212 ? 57.252 -45.025 58.009 1.00 140.19 ? 212 VAL F CG2 1 +ATOM 11071 N N . MET F 1 213 ? 57.422 -41.902 61.063 1.00 58.81 ? 213 MET F N 1 +ATOM 11072 C CA . MET F 1 213 ? 57.397 -40.820 62.041 1.00 87.26 ? 213 MET F CA 1 +ATOM 11073 C C . MET F 1 213 ? 58.742 -40.553 62.766 1.00 95.97 ? 213 MET F C 1 +ATOM 11074 O O . MET F 1 213 ? 59.247 -39.415 62.814 1.00 116.23 ? 213 MET F O 1 +ATOM 11075 C CB . MET F 1 213 ? 56.308 -41.202 63.060 1.00 89.50 ? 213 MET F CB 1 +ATOM 11076 C CG . MET F 1 213 ? 55.935 -40.183 64.107 1.00 95.74 ? 213 MET F CG 1 +ATOM 11077 S SD . MET F 1 213 ? 54.624 -40.879 65.092 1.00 102.65 ? 213 MET F SD 1 +ATOM 11078 C CE . MET F 1 213 ? 55.566 -41.180 66.579 1.00 160.22 ? 213 MET F CE 1 +ATOM 11079 N N . LEU F 1 214 ? 59.303 -41.612 63.338 1.00 133.65 ? 214 LEU F N 1 +ATOM 11080 C CA . LEU F 1 214 ? 60.397 -41.517 64.315 1.00 135.43 ? 214 LEU F CA 1 +ATOM 11081 C C . LEU F 1 214 ? 61.736 -41.476 63.592 1.00 118.63 ? 214 LEU F C 1 +ATOM 11082 O O . LEU F 1 214 ? 62.664 -40.791 64.030 1.00 106.09 ? 214 LEU F O 1 +ATOM 11083 C CB . LEU F 1 214 ? 60.372 -42.722 65.259 1.00 113.98 ? 214 LEU F CB 1 +ATOM 11084 C CG . LEU F 1 214 ? 60.607 -42.476 66.753 1.00 129.27 ? 214 LEU F CG 1 +ATOM 11085 C CD1 . LEU F 1 214 ? 59.568 -41.522 67.391 1.00 136.26 ? 214 LEU F CD1 1 +ATOM 11086 C CD2 . LEU F 1 214 ? 60.616 -43.829 67.463 1.00 130.05 ? 214 LEU F CD2 1 +ATOM 11087 N N . CYS F 1 215 ? 61.765 -42.078 62.415 1.00 104.49 ? 215 CYS F N 1 +ATOM 11088 C CA . CYS F 1 215 ? 62.913 -41.956 61.533 1.00 117.48 ? 215 CYS F CA 1 +ATOM 11089 C C . CYS F 1 215 ? 63.041 -40.551 60.925 1.00 115.38 ? 215 CYS F C 1 +ATOM 11090 O O . CYS F 1 215 ? 64.161 -39.998 60.781 1.00 99.14 ? 215 CYS F O 1 +ATOM 11091 C CB . CYS F 1 215 ? 62.777 -42.960 60.401 1.00 158.18 ? 215 CYS F CB 1 +ATOM 11092 S SG . CYS F 1 215 ? 62.751 -44.658 60.974 1.00 207.77 ? 215 CYS F SG 1 +ATOM 11093 N N . LEU F 1 216 ? 61.899 -39.996 60.501 1.00 89.79 ? 216 LEU F N 1 +ATOM 11094 C CA . LEU F 1 216 ? 61.866 -38.628 60.010 1.00 82.37 ? 216 LEU F CA 1 +ATOM 11095 C C . LEU F 1 216 ? 62.429 -37.667 61.070 1.00 90.56 ? 216 LEU F C 1 +ATOM 11096 O O . LEU F 1 216 ? 63.328 -36.865 60.806 1.00 94.43 ? 216 LEU F O 1 +ATOM 11097 C CB . LEU F 1 216 ? 60.451 -38.226 59.648 1.00 63.12 ? 216 LEU F CB 1 +ATOM 11098 C CG . LEU F 1 216 ? 60.309 -36.782 59.166 1.00 68.98 ? 216 LEU F CG 1 +ATOM 11099 C CD1 . LEU F 1 216 ? 61.166 -36.471 57.940 1.00 77.00 ? 216 LEU F CD1 1 +ATOM 11100 C CD2 . LEU F 1 216 ? 58.856 -36.492 58.818 1.00 88.70 ? 216 LEU F CD2 1 +ATOM 11101 N N . MET F 1 217 ? 61.959 -37.828 62.297 1.00 96.46 ? 217 MET F N 1 +ATOM 11102 C CA . MET F 1 217 ? 62.398 -36.975 63.389 1.00 76.72 ? 217 MET F CA 1 +ATOM 11103 C C . MET F 1 217 ? 63.901 -37.081 63.582 1.00 49.60 ? 217 MET F C 1 +ATOM 11104 O O . MET F 1 217 ? 64.597 -36.090 63.722 1.00 36.39 ? 217 MET F O 1 +ATOM 11105 C CB . MET F 1 217 ? 61.620 -37.308 64.687 1.00 91.83 ? 217 MET F CB 1 +ATOM 11106 C CG . MET F 1 217 ? 61.132 -36.075 65.434 1.00 112.40 ? 217 MET F CG 1 +ATOM 11107 S SD . MET F 1 217 ? 62.488 -35.137 66.176 1.00 151.73 ? 217 MET F SD 1 +ATOM 11108 C CE . MET F 1 217 ? 61.675 -33.631 66.719 1.00 161.72 ? 217 MET F CE 1 +ATOM 11109 N N . SER F 1 218 ? 64.388 -38.304 63.616 1.00 61.86 ? 218 SER F N 1 +ATOM 11110 C CA . SER F 1 218 ? 65.818 -38.570 63.857 1.00 93.49 ? 218 SER F CA 1 +ATOM 11111 C C . SER F 1 218 ? 66.653 -37.858 62.817 1.00 73.16 ? 218 SER F C 1 +ATOM 11112 O O . SER F 1 218 ? 67.637 -37.201 63.147 1.00 66.95 ? 218 SER F O 1 +ATOM 11113 C CB . SER F 1 218 ? 66.092 -40.100 63.823 1.00 109.39 ? 218 SER F CB 1 +ATOM 11114 O OG . SER F 1 218 ? 67.437 -40.402 64.222 1.00 57.09 ? 218 SER F OG 1 +ATOM 11115 N N . ALA F 1 219 ? 66.244 -38.014 61.562 1.00 71.25 ? 219 ALA F N 1 +ATOM 11116 C CA . ALA F 1 219 ? 67.041 -37.537 60.445 1.00 76.74 ? 219 ALA F CA 1 +ATOM 11117 C C . ALA F 1 219 ? 67.068 -35.986 60.442 1.00 72.64 ? 219 ALA F C 1 +ATOM 11118 O O . ALA F 1 219 ? 68.076 -35.370 60.101 1.00 73.50 ? 219 ALA F O 1 +ATOM 11119 C CB . ALA F 1 219 ? 66.492 -38.094 59.135 1.00 67.61 ? 219 ALA F CB 1 +ATOM 11120 N N . ILE F 1 220 ? 66.000 -35.376 60.913 1.00 61.59 ? 220 ILE F N 1 +ATOM 11121 C CA . ILE F 1 220 ? 65.935 -33.923 60.967 1.00 78.99 ? 220 ILE F CA 1 +ATOM 11122 C C . ILE F 1 220 ? 66.854 -33.390 62.054 1.00 75.98 ? 220 ILE F C 1 +ATOM 11123 O O . ILE F 1 220 ? 67.546 -32.402 61.864 1.00 87.88 ? 220 ILE F O 1 +ATOM 11124 C CB . ILE F 1 220 ? 64.477 -33.432 61.222 1.00 134.07 ? 220 ILE F CB 1 +ATOM 11125 C CG1 . ILE F 1 220 ? 63.598 -33.684 59.977 1.00 127.61 ? 220 ILE F CG1 1 +ATOM 11126 C CG2 . ILE F 1 220 ? 64.453 -31.951 61.604 1.00 132.95 ? 220 ILE F CG2 1 +ATOM 11127 C CD1 . ILE F 1 220 ? 62.100 -33.621 60.230 1.00 77.04 ? 220 ILE F CD1 1 +ATOM 11128 N N . GLU F 1 221 ? 66.891 -34.074 63.189 1.00 88.12 ? 221 GLU F N 1 +ATOM 11129 C CA . GLU F 1 221 ? 67.827 -33.718 64.266 1.00 99.46 ? 221 GLU F CA 1 +ATOM 11130 C C . GLU F 1 221 ? 69.267 -33.745 63.755 1.00 95.07 ? 221 GLU F C 1 +ATOM 11131 O O . GLU F 1 221 ? 70.027 -32.787 63.929 1.00 87.05 ? 221 GLU F O 1 +ATOM 11132 C CB . GLU F 1 221 ? 67.672 -34.695 65.454 1.00 124.28 ? 221 GLU F CB 1 +ATOM 11133 C CG . GLU F 1 221 ? 66.403 -34.464 66.269 1.00 139.55 ? 221 GLU F CG 1 +ATOM 11134 C CD . GLU F 1 221 ? 66.009 -35.635 67.150 1.00 128.70 ? 221 GLU F CD 1 +ATOM 11135 O OE1 . GLU F 1 221 ? 66.225 -36.820 66.759 1.00 120.57 ? 221 GLU F OE1 1 +ATOM 11136 O OE2 . GLU F 1 221 ? 65.504 -35.365 68.258 1.00 113.90 ? 221 GLU F OE2 1 +ATOM 11137 N N . THR F 1 222 ? 69.635 -34.879 63.153 1.00 91.20 ? 222 THR F N 1 +ATOM 11138 C CA . THR F 1 222 ? 70.952 -35.078 62.541 1.00 78.68 ? 222 THR F CA 1 +ATOM 11139 C C . THR F 1 222 ? 71.310 -33.928 61.602 1.00 79.28 ? 222 THR F C 1 +ATOM 11140 O O . THR F 1 222 ? 72.406 -33.376 61.675 1.00 74.80 ? 222 THR F O 1 +ATOM 11141 C CB . THR F 1 222 ? 70.973 -36.396 61.731 1.00 77.65 ? 222 THR F CB 1 +ATOM 11142 O OG1 . THR F 1 222 ? 70.948 -37.519 62.629 1.00 66.95 ? 222 THR F OG1 1 +ATOM 11143 C CG2 . THR F 1 222 ? 72.194 -36.461 60.793 1.00 81.81 ? 222 THR F CG2 1 +ATOM 11144 N N . GLY F 1 223 ? 70.374 -33.585 60.720 1.00 99.09 ? 223 GLY F N 1 +ATOM 11145 C CA . GLY F 1 223 ? 70.529 -32.441 59.823 1.00 113.03 ? 223 GLY F CA 1 +ATOM 11146 C C . GLY F 1 223 ? 70.802 -31.134 60.557 1.00 111.47 ? 223 GLY F C 1 +ATOM 11147 O O . GLY F 1 223 ? 71.638 -30.343 60.125 1.00 105.69 ? 223 GLY F O 1 +ATOM 11148 N N . VAL F 1 224 ? 70.107 -30.916 61.679 1.00 112.57 ? 224 VAL F N 1 +ATOM 11149 C CA . VAL F 1 224 ? 70.296 -29.709 62.457 1.00 112.22 ? 224 VAL F CA 1 +ATOM 11150 C C . VAL F 1 224 ? 71.731 -29.664 62.995 1.00 124.33 ? 224 VAL F C 1 +ATOM 11151 O O . VAL F 1 224 ? 72.388 -28.610 62.961 1.00 107.84 ? 224 VAL F O 1 +ATOM 11152 C CB . VAL F 1 224 ? 69.303 -29.611 63.627 1.00 107.60 ? 224 VAL F CB 1 +ATOM 11153 C CG1 . VAL F 1 224 ? 69.668 -28.417 64.512 1.00 136.39 ? 224 VAL F CG1 1 +ATOM 11154 C CG2 . VAL F 1 224 ? 67.884 -29.488 63.115 1.00 77.40 ? 224 VAL F CG2 1 +ATOM 11155 N N . ILE F 1 225 ? 72.227 -30.805 63.473 1.00 109.68 ? 225 ILE F N 1 +ATOM 11156 C CA . ILE F 1 225 ? 73.599 -30.873 63.963 1.00 103.98 ? 225 ILE F CA 1 +ATOM 11157 C C . ILE F 1 225 ? 74.595 -30.519 62.857 1.00 99.66 ? 225 ILE F C 1 +ATOM 11158 O O . ILE F 1 225 ? 75.436 -29.634 63.056 1.00 82.30 ? 225 ILE F O 1 +ATOM 11159 C CB . ILE F 1 225 ? 73.938 -32.245 64.553 1.00 87.36 ? 225 ILE F CB 1 +ATOM 11160 C CG1 . ILE F 1 225 ? 73.148 -32.471 65.846 1.00 82.93 ? 225 ILE F CG1 1 +ATOM 11161 C CG2 . ILE F 1 225 ? 75.428 -32.323 64.871 1.00 106.51 ? 225 ILE F CG2 1 +ATOM 11162 C CD1 . ILE F 1 225 ? 73.090 -33.921 66.266 1.00 108.94 ? 225 ILE F CD1 1 +ATOM 11163 N N . PHE F 1 226 ? 74.479 -31.183 61.702 1.00 98.56 ? 226 PHE F N 1 +ATOM 11164 C CA . PHE F 1 226 ? 75.361 -30.907 60.551 1.00 109.07 ? 226 PHE F CA 1 +ATOM 11165 C C . PHE F 1 226 ? 75.313 -29.443 60.144 1.00 110.61 ? 226 PHE F C 1 +ATOM 11166 O O . PHE F 1 226 ? 76.314 -28.881 59.710 1.00 124.80 ? 226 PHE F O 1 +ATOM 11167 C CB . PHE F 1 226 ? 75.002 -31.780 59.345 1.00 111.80 ? 226 PHE F CB 1 +ATOM 11168 C CG . PHE F 1 226 ? 75.540 -33.198 59.427 1.00 141.55 ? 226 PHE F CG 1 +ATOM 11169 C CD1 . PHE F 1 226 ? 76.912 -33.441 59.527 1.00 154.99 ? 226 PHE F CD1 1 +ATOM 11170 C CD2 . PHE F 1 226 ? 74.682 -34.296 59.361 1.00 116.72 ? 226 PHE F CD2 1 +ATOM 11171 C CE1 . PHE F 1 226 ? 77.406 -34.742 59.576 1.00 123.64 ? 226 PHE F CE1 1 +ATOM 11172 C CE2 . PHE F 1 226 ? 75.175 -35.594 59.391 1.00 86.75 ? 226 PHE F CE2 1 +ATOM 11173 C CZ . PHE F 1 226 ? 76.531 -35.818 59.507 1.00 97.30 ? 226 PHE F CZ 1 +ATOM 11174 N N . LEU F 1 227 ? 74.154 -28.813 60.325 1.00 134.02 ? 227 LEU F N 1 +ATOM 11175 C CA . LEU F 1 227 ? 73.992 -27.388 60.018 1.00 135.13 ? 227 LEU F CA 1 +ATOM 11176 C C . LEU F 1 227 ? 74.751 -26.521 60.999 1.00 137.73 ? 227 LEU F C 1 +ATOM 11177 O O . LEU F 1 227 ? 75.454 -25.598 60.582 1.00 181.88 ? 227 LEU F O 1 +ATOM 11178 C CB . LEU F 1 227 ? 72.517 -27.012 60.043 1.00 125.34 ? 227 LEU F CB 1 +ATOM 11179 C CG . LEU F 1 227 ? 71.698 -27.405 58.807 1.00 161.79 ? 227 LEU F CG 1 +ATOM 11180 C CD1 . LEU F 1 227 ? 70.191 -27.306 58.971 1.00 174.21 ? 227 LEU F CD1 1 +ATOM 11181 C CD2 . LEU F 1 227 ? 72.124 -26.620 57.576 1.00 132.33 ? 227 LEU F CD2 1 +ATOM 11182 N N . ILE F 1 228 ? 74.670 -26.859 62.285 1.00 106.78 ? 228 ILE F N 1 +ATOM 11183 C CA . ILE F 1 228 ? 75.370 -26.094 63.315 1.00 104.98 ? 228 ILE F CA 1 +ATOM 11184 C C . ILE F 1 228 ? 76.878 -26.235 63.151 1.00 109.46 ? 228 ILE F C 1 +ATOM 11185 O O . ILE F 1 228 ? 77.610 -25.238 63.135 1.00 110.61 ? 228 ILE F O 1 +ATOM 11186 C CB . ILE F 1 228 ? 75.005 -26.539 64.742 1.00 96.16 ? 228 ILE F CB 1 +ATOM 11187 C CG1 . ILE F 1 228 ? 73.522 -26.283 65.029 1.00 94.68 ? 228 ILE F CG1 1 +ATOM 11188 C CG2 . ILE F 1 228 ? 75.836 -25.768 65.755 1.00 89.88 ? 228 ILE F CG2 1 +ATOM 11189 C CD1 . ILE F 1 228 ? 72.976 -27.004 66.248 1.00 80.77 ? 228 ILE F CD1 1 +ATOM 11190 N N . ASN F 1 229 ? 77.332 -27.469 62.965 1.00 110.98 ? 229 ASN F N 1 +ATOM 11191 C CA . ASN F 1 229 ? 78.757 -27.745 62.772 1.00 125.60 ? 229 ASN F CA 1 +ATOM 11192 C C . ASN F 1 229 ? 79.308 -27.030 61.536 1.00 122.23 ? 229 ASN F C 1 +ATOM 11193 O O . ASN F 1 229 ? 80.360 -26.395 61.587 1.00 139.27 ? 229 ASN F O 1 +ATOM 11194 C CB . ASN F 1 229 ? 78.985 -29.259 62.654 1.00 125.28 ? 229 ASN F CB 1 +ATOM 11195 C CG . ASN F 1 229 ? 80.429 -29.660 62.878 1.00 132.99 ? 229 ASN F CG 1 +ATOM 11196 O OD1 . ASN F 1 229 ? 81.208 -28.929 63.501 1.00 107.82 ? 229 ASN F OD1 1 +ATOM 11197 N ND2 . ASN F 1 229 ? 80.800 -30.823 62.353 1.00 154.38 ? 229 ASN F ND2 1 +ATOM 11198 N N . ASP F 1 230 ? 78.557 -27.097 60.442 1.00 123.34 ? 230 ASP F N 1 +ATOM 11199 C CA . ASP F 1 230 ? 78.923 -26.419 59.209 1.00 116.15 ? 230 ASP F CA 1 +ATOM 11200 C C . ASP F 1 230 ? 79.018 -24.910 59.444 1.00 130.40 ? 230 ASP F C 1 +ATOM 11201 O O . ASP F 1 230 ? 79.912 -24.246 58.930 1.00 127.22 ? 230 ASP F O 1 +ATOM 11202 C CB . ASP F 1 230 ? 77.896 -26.728 58.114 1.00 131.53 ? 230 ASP F CB 1 +ATOM 11203 C CG . ASP F 1 230 ? 78.307 -26.185 56.765 1.00 139.03 ? 230 ASP F CG 1 +ATOM 11204 O OD1 . ASP F 1 230 ? 79.262 -26.757 56.191 1.00 74.06 ? 230 ASP F OD1 1 +ATOM 11205 O OD2 . ASP F 1 230 ? 77.663 -25.177 56.300 1.00 227.29 ? 230 ASP F OD2 1 +ATOM 11206 N N . GLY F 1 231 ? 78.066 -24.360 60.196 1.00 142.89 ? 231 GLY F N 1 +ATOM 11207 C CA . GLY F 1 231 ? 78.044 -22.926 60.470 1.00 138.83 ? 231 GLY F CA 1 +ATOM 11208 C C . GLY F 1 231 ? 79.220 -22.508 61.335 1.00 131.19 ? 231 GLY F C 1 +ATOM 11209 O O . GLY F 1 231 ? 79.749 -21.395 61.185 1.00 145.77 ? 231 GLY F O 1 +ATOM 11210 N N . ILE F 1 232 ? 79.612 -23.390 62.258 1.00 110.53 ? 232 ILE F N 1 +ATOM 11211 C CA . ILE F 1 232 ? 80.783 -23.150 63.102 1.00 104.26 ? 232 ILE F CA 1 +ATOM 11212 C C . ILE F 1 232 ? 82.032 -23.038 62.246 1.00 108.53 ? 232 ILE F C 1 +ATOM 11213 O O . ILE F 1 232 ? 82.783 -22.066 62.360 1.00 106.58 ? 232 ILE F O 1 +ATOM 11214 C CB . ILE F 1 232 ? 80.971 -24.267 64.138 1.00 113.96 ? 232 ILE F CB 1 +ATOM 11215 C CG1 . ILE F 1 232 ? 79.907 -24.137 65.238 1.00 126.83 ? 232 ILE F CG1 1 +ATOM 11216 C CG2 . ILE F 1 232 ? 82.379 -24.226 64.740 1.00 130.20 ? 232 ILE F CG2 1 +ATOM 11217 C CD1 . ILE F 1 232 ? 79.723 -25.387 66.074 1.00 130.68 ? 232 ILE F CD1 1 +ATOM 11218 N N . ASP F 1 233 ? 82.216 -24.008 61.352 1.00 124.78 ? 233 ASP F N 1 +ATOM 11219 C CA . ASP F 1 233 ? 83.338 -24.005 60.408 1.00 132.66 ? 233 ASP F CA 1 +ATOM 11220 C C . ASP F 1 233 ? 83.354 -22.728 59.565 1.00 121.31 ? 233 ASP F C 1 +ATOM 11221 O O . ASP F 1 233 ? 84.391 -22.076 59.437 1.00 122.27 ? 233 ASP F O 1 +ATOM 11222 C CB . ASP F 1 233 ? 83.273 -25.226 59.474 1.00 149.65 ? 233 ASP F CB 1 +ATOM 11223 C CG . ASP F 1 233 ? 83.459 -26.554 60.211 1.00 143.23 ? 233 ASP F CG 1 +ATOM 11224 O OD1 . ASP F 1 233 ? 83.453 -26.561 61.457 1.00 132.91 ? 233 ASP F OD1 1 +ATOM 11225 O OD2 . ASP F 1 233 ? 83.597 -27.595 59.528 1.00 104.40 ? 233 ASP F OD2 1 +ATOM 11226 N N . ARG F 1 234 ? 82.204 -22.365 59.005 1.00 133.68 ? 234 ARG F N 1 +ATOM 11227 C CA . ARG F 1 234 ? 82.127 -21.248 58.047 1.00 159.09 ? 234 ARG F CA 1 +ATOM 11228 C C . ARG F 1 234 ? 82.029 -19.870 58.693 1.00 143.51 ? 234 ARG F C 1 +ATOM 11229 O O . ARG F 1 234 ? 81.996 -18.857 57.997 1.00 113.77 ? 234 ARG F O 1 +ATOM 11230 C CB . ARG F 1 234 ? 80.946 -21.454 57.104 1.00 183.50 ? 234 ARG F CB 1 +ATOM 11231 C CG . ARG F 1 234 ? 81.211 -22.558 56.101 1.00 192.40 ? 234 ARG F CG 1 +ATOM 11232 C CD . ARG F 1 234 ? 79.942 -23.135 55.517 1.00 151.48 ? 234 ARG F CD 1 +ATOM 11233 N NE . ARG F 1 234 ? 80.301 -24.227 54.622 1.00 121.05 ? 234 ARG F NE 1 +ATOM 11234 C CZ . ARG F 1 234 ? 79.989 -24.271 53.334 1.00 134.04 ? 234 ARG F CZ 1 +ATOM 11235 N NH1 . ARG F 1 234 ? 79.198 -23.333 52.806 1.00 108.43 ? 234 ARG F NH1 1 +ATOM 11236 N NH2 . ARG F 1 234 ? 80.407 -25.296 52.590 1.00 140.08 ? 234 ARG F NH2 1 +ATOM 11237 N N . GLY F 1 235 ? 82.015 -19.833 60.023 1.00 141.51 ? 235 GLY F N 1 +ATOM 11238 C CA . GLY F 1 235 ? 82.037 -18.573 60.756 1.00 111.94 ? 235 GLY F CA 1 +ATOM 11239 C C . GLY F 1 235 ? 80.697 -17.869 60.751 1.00 110.95 ? 235 GLY F C 1 +ATOM 11240 O O . GLY F 1 235 ? 80.649 -16.634 60.757 1.00 106.49 ? 235 GLY F O 1 +ATOM 11241 N N . LEU F 1 236 ? 79.605 -18.634 60.720 1.00 110.48 ? 236 LEU F N 1 +ATOM 11242 C CA . LEU F 1 236 ? 78.281 -18.048 60.958 1.00 123.77 ? 236 LEU F CA 1 +ATOM 11243 C C . LEU F 1 236 ? 78.129 -17.712 62.440 1.00 111.90 ? 236 LEU F C 1 +ATOM 11244 O O . LEU F 1 236 ? 77.723 -16.605 62.804 1.00 103.43 ? 236 LEU F O 1 +ATOM 11245 C CB . LEU F 1 236 ? 77.149 -18.990 60.527 1.00 147.24 ? 236 LEU F CB 1 +ATOM 11246 C CG . LEU F 1 236 ? 76.741 -19.000 59.045 1.00 160.47 ? 236 LEU F CG 1 +ATOM 11247 C CD1 . LEU F 1 236 ? 77.733 -19.818 58.231 1.00 163.42 ? 236 LEU F CD1 1 +ATOM 11248 C CD2 . LEU F 1 236 ? 75.331 -19.558 58.879 1.00 142.80 ? 236 LEU F CD2 1 +ATOM 11249 N N . TRP F 1 237 ? 78.473 -18.671 63.287 1.00 108.23 ? 237 TRP F N 1 +ATOM 11250 C CA . TRP F 1 237 ? 78.345 -18.508 64.731 1.00 130.22 ? 237 TRP F CA 1 +ATOM 11251 C C . TRP F 1 237 ? 79.553 -19.130 65.443 1.00 158.18 ? 237 TRP F C 1 +ATOM 11252 O O . TRP F 1 237 ? 80.329 -19.874 64.834 1.00 144.90 ? 237 TRP F O 1 +ATOM 11253 C CB . TRP F 1 237 ? 77.038 -19.134 65.222 1.00 118.40 ? 237 TRP F CB 1 +ATOM 11254 C CG . TRP F 1 237 ? 76.638 -20.335 64.441 1.00 127.86 ? 237 TRP F CG 1 +ATOM 11255 C CD1 . TRP F 1 237 ? 77.292 -21.531 64.392 1.00 150.66 ? 237 TRP F CD1 1 +ATOM 11256 C CD2 . TRP F 1 237 ? 75.500 -20.467 63.577 1.00 134.58 ? 237 TRP F CD2 1 +ATOM 11257 N NE1 . TRP F 1 237 ? 76.636 -22.401 63.555 1.00 160.24 ? 237 TRP F NE1 1 +ATOM 11258 C CE2 . TRP F 1 237 ? 75.523 -21.781 63.051 1.00 150.49 ? 237 TRP F CE2 1 +ATOM 11259 C CE3 . TRP F 1 237 ? 74.469 -19.609 63.196 1.00 118.42 ? 237 TRP F CE3 1 +ATOM 11260 C CZ2 . TRP F 1 237 ? 74.563 -22.249 62.144 1.00 130.91 ? 237 TRP F CZ2 1 +ATOM 11261 C CZ3 . TRP F 1 237 ? 73.508 -20.083 62.310 1.00 121.71 ? 237 TRP F CZ3 1 +ATOM 11262 C CH2 . TRP F 1 237 ? 73.560 -21.394 61.800 1.00 120.27 ? 237 TRP F CH2 1 +ATOM 11263 N N . ASP F 1 238 ? 79.725 -18.792 66.720 1.00 176.00 ? 238 ASP F N 1 +ATOM 11264 C CA . ASP F 1 238 ? 80.931 -19.161 67.463 1.00 171.00 ? 238 ASP F CA 1 +ATOM 11265 C C . ASP F 1 238 ? 80.611 -19.829 68.796 1.00 155.22 ? 238 ASP F C 1 +ATOM 11266 O O . ASP F 1 238 ? 79.624 -19.486 69.460 1.00 113.16 ? 238 ASP F O 1 +ATOM 11267 C CB . ASP F 1 238 ? 81.830 -17.939 67.701 1.00 178.59 ? 238 ASP F CB 1 +ATOM 11268 C CG . ASP F 1 238 ? 82.229 -17.237 66.409 1.00 166.48 ? 238 ASP F CG 1 +ATOM 11269 O OD1 . ASP F 1 238 ? 81.400 -16.467 65.889 1.00 171.35 ? 238 ASP F OD1 1 +ATOM 11270 O OD2 . ASP F 1 238 ? 83.361 -17.449 65.922 1.00 116.42 ? 238 ASP F OD2 1 +ATOM 11271 N N . LEU F 1 239 ? 81.497 -20.737 69.207 1.00 156.95 ? 239 LEU F N 1 +ATOM 11272 C CA . LEU F 1 239 ? 81.346 -21.462 70.461 1.00 153.47 ? 239 LEU F CA 1 +ATOM 11273 C C . LEU F 1 239 ? 81.723 -20.582 71.645 1.00 159.43 ? 239 LEU F C 1 +ATOM 11274 O O . LEU F 1 239 ? 82.628 -19.745 71.557 1.00 161.19 ? 239 LEU F O 1 +ATOM 11275 C CB . LEU F 1 239 ? 82.228 -22.714 70.471 1.00 168.07 ? 239 LEU F CB 1 +ATOM 11276 C CG . LEU F 1 239 ? 81.796 -23.943 69.675 1.00 168.63 ? 239 LEU F CG 1 +ATOM 11277 C CD1 . LEU F 1 239 ? 82.754 -25.102 69.916 1.00 180.94 ? 239 LEU F CD1 1 +ATOM 11278 C CD2 . LEU F 1 239 ? 80.387 -24.351 70.045 1.00 164.53 ? 239 LEU F CD2 1 +ATOM 11279 N N . GLN F 1 240 ? 81.004 -20.764 72.750 1.00 152.15 ? 240 GLN F N 1 +ATOM 11280 C CA . GLN F 1 240 ? 81.381 -20.146 74.024 1.00 134.84 ? 240 GLN F CA 1 +ATOM 11281 C C . GLN F 1 240 ? 82.824 -20.497 74.390 1.00 141.70 ? 240 GLN F C 1 +ATOM 11282 O O . GLN F 1 240 ? 83.659 -19.613 74.572 1.00 153.78 ? 240 GLN F O 1 +ATOM 11283 C CB . GLN F 1 240 ? 80.434 -20.614 75.137 1.00 132.13 ? 240 GLN F CB 1 +ATOM 11284 C CG . GLN F 1 240 ? 80.619 -19.874 76.454 1.00 117.67 ? 240 GLN F CG 1 +ATOM 11285 C CD . GLN F 1 240 ? 80.256 -18.405 76.338 1.00 132.22 ? 240 GLN F CD 1 +ATOM 11286 O OE1 . GLN F 1 240 ? 79.074 -18.040 76.381 1.00 158.23 ? 240 GLN F OE1 1 +ATOM 11287 N NE2 . GLN F 1 240 ? 81.262 -17.556 76.143 1.00 134.63 ? 240 GLN F NE2 1 +ATOM 11288 N N . ASN F 1 241 ? 83.096 -21.798 74.464 1.00 128.97 ? 241 ASN F N 1 +ATOM 11289 C CA . ASN F 1 241 ? 84.421 -22.309 74.757 1.00 106.09 ? 241 ASN F CA 1 +ATOM 11290 C C . ASN F 1 241 ? 85.097 -22.825 73.502 1.00 142.63 ? 241 ASN F C 1 +ATOM 11291 O O . ASN F 1 241 ? 84.712 -23.878 72.955 1.00 179.42 ? 241 ASN F O 1 +ATOM 11292 C CB . ASN F 1 241 ? 84.314 -23.440 75.753 1.00 90.00 ? 241 ASN F CB 1 +ATOM 11293 C CG . ASN F 1 241 ? 84.651 -22.997 77.147 1.00 105.40 ? 241 ASN F CG 1 +ATOM 11294 O OD1 . ASN F 1 241 ? 85.746 -23.261 77.638 1.00 119.97 ? 241 ASN F OD1 1 +ATOM 11295 N ND2 . ASN F 1 241 ? 83.719 -22.309 77.801 1.00 132.93 ? 241 ASN F ND2 1 +ATOM 11296 N N . LYS F 1 242 ? 86.130 -22.113 73.059 1.00 143.28 ? 242 LYS F N 1 +ATOM 11297 C CA . LYS F 1 242 ? 86.872 -22.519 71.863 1.00 157.62 ? 242 LYS F CA 1 +ATOM 11298 C C . LYS F 1 242 ? 87.587 -23.848 72.114 1.00 166.03 ? 242 LYS F C 1 +ATOM 11299 O O . LYS F 1 242 ? 87.828 -24.626 71.181 1.00 151.21 ? 242 LYS F O 1 +ATOM 11300 C CB . LYS F 1 242 ? 87.870 -21.433 71.453 1.00 161.66 ? 242 LYS F CB 1 +ATOM 11301 C CG . LYS F 1 242 ? 87.263 -20.036 71.386 1.00 166.47 ? 242 LYS F CG 1 +ATOM 11302 C CD . LYS F 1 242 ? 87.499 -19.370 70.040 1.00 160.51 ? 242 LYS F CD 1 +ATOM 11303 C CE . LYS F 1 242 ? 86.222 -18.736 69.510 1.00 154.57 ? 242 LYS F CE 1 +ATOM 11304 N NZ . LYS F 1 242 ? 86.449 -17.943 68.272 1.00 159.41 ? 242 LYS F NZ 1 +ATOM 11305 N N . ALA F 1 243 ? 87.861 -24.109 73.395 1.00 192.42 ? 243 ALA F N 1 +ATOM 11306 C CA . ALA F 1 243 ? 88.406 -25.384 73.871 1.00 202.15 ? 243 ALA F CA 1 +ATOM 11307 C C . ALA F 1 243 ? 87.461 -26.548 73.593 1.00 197.90 ? 243 ALA F C 1 +ATOM 11308 O O . ALA F 1 243 ? 87.891 -27.704 73.594 1.00 222.87 ? 243 ALA F O 1 +ATOM 11309 C CB . ALA F 1 243 ? 88.698 -25.308 75.367 1.00 198.53 ? 243 ALA F CB 1 +ATOM 11310 N N . GLU F 1 244 ? 86.180 -26.251 73.363 1.00 178.36 ? 244 GLU F N 1 +ATOM 11311 C CA . GLU F 1 244 ? 85.200 -27.307 73.133 1.00 150.75 ? 244 GLU F CA 1 +ATOM 11312 C C . GLU F 1 244 ? 85.024 -27.629 71.655 1.00 140.94 ? 244 GLU F C 1 +ATOM 11313 O O . GLU F 1 244 ? 84.098 -28.335 71.301 1.00 102.48 ? 244 GLU F O 1 +ATOM 11314 C CB . GLU F 1 244 ? 83.852 -26.935 73.750 1.00 157.52 ? 244 GLU F CB 1 +ATOM 11315 C CG . GLU F 1 244 ? 83.822 -27.016 75.262 1.00 168.13 ? 244 GLU F CG 1 +ATOM 11316 C CD . GLU F 1 244 ? 82.413 -26.910 75.819 1.00 177.63 ? 244 GLU F CD 1 +ATOM 11317 O OE1 . GLU F 1 244 ? 81.884 -25.770 75.887 1.00 146.19 ? 244 GLU F OE1 1 +ATOM 11318 O OE2 . GLU F 1 244 ? 81.869 -27.963 76.247 1.00 137.84 ? 244 GLU F OE2 1 +ATOM 11319 N N . ARG F 1 245 ? 85.898 -27.100 70.797 1.00 158.28 ? 245 ARG F N 1 +ATOM 11320 C CA . ARG F 1 245 ? 85.881 -27.452 69.377 1.00 162.70 ? 245 ARG F CA 1 +ATOM 11321 C C . ARG F 1 245 ? 86.022 -28.955 69.137 1.00 182.37 ? 245 ARG F C 1 +ATOM 11322 O O . ARG F 1 245 ? 85.406 -29.488 68.215 1.00 199.39 ? 245 ARG F O 1 +ATOM 11323 C CB . ARG F 1 245 ? 86.979 -26.739 68.604 1.00 162.48 ? 245 ARG F CB 1 +ATOM 11324 C CG . ARG F 1 245 ? 86.873 -26.932 67.089 1.00 180.01 ? 245 ARG F CG 1 +ATOM 11325 C CD . ARG F 1 245 ? 87.922 -26.123 66.296 1.00 185.19 ? 245 ARG F CD 1 +ATOM 11326 N NE . ARG F 1 245 ? 87.379 -24.865 65.774 1.00 177.91 ? 245 ARG F NE 1 +ATOM 11327 C CZ . ARG F 1 245 ? 86.501 -24.774 64.774 1.00 170.06 ? 245 ARG F CZ 1 +ATOM 11328 N NH1 . ARG F 1 245 ? 86.042 -25.863 64.185 1.00 176.54 ? 245 ARG F NH1 1 +ATOM 11329 N NH2 . ARG F 1 245 ? 86.052 -23.591 64.375 1.00 150.14 ? 245 ARG F NH2 1 +ATOM 11330 N N . GLN F 1 246 ? 86.832 -29.631 69.953 1.00 181.24 ? 246 GLN F N 1 +ATOM 11331 C CA . GLN F 1 246 ? 87.079 -31.066 69.765 1.00 160.48 ? 246 GLN F CA 1 +ATOM 11332 C C . GLN F 1 246 ? 86.110 -31.919 70.586 1.00 147.39 ? 246 GLN F C 1 +ATOM 11333 O O . GLN F 1 246 ? 86.389 -33.077 70.875 1.00 133.74 ? 246 GLN F O 1 +ATOM 11334 C CB . GLN F 1 246 ? 88.528 -31.426 70.108 1.00 155.24 ? 246 GLN F CB 1 +ATOM 11335 C CG . GLN F 1 246 ? 89.554 -30.910 69.115 1.00 170.34 ? 246 GLN F CG 1 +ATOM 11336 C CD . GLN F 1 246 ? 89.796 -29.424 69.264 1.00 202.88 ? 246 GLN F CD 1 +ATOM 11337 O OE1 . GLN F 1 246 ? 89.962 -28.917 70.379 1.00 238.04 ? 246 GLN F OE1 1 +ATOM 11338 N NE2 . GLN F 1 246 ? 89.854 -28.718 68.140 1.00 230.11 ? 246 GLN F NE2 1 +ATOM 11339 N N . ASN F 1 247 ? 84.975 -31.333 70.957 1.00 139.66 ? 247 ASN F N 1 +ATOM 11340 C CA . ASN F 1 247 ? 83.844 -32.072 71.519 1.00 138.28 ? 247 ASN F CA 1 +ATOM 11341 C C . ASN F 1 247 ? 83.603 -33.394 70.784 1.00 145.80 ? 247 ASN F C 1 +ATOM 11342 O O . ASN F 1 247 ? 83.655 -33.437 69.552 1.00 153.17 ? 247 ASN F O 1 +ATOM 11343 C CB . ASN F 1 247 ? 82.585 -31.208 71.420 1.00 155.00 ? 247 ASN F CB 1 +ATOM 11344 C CG . ASN F 1 247 ? 81.551 -31.550 72.465 1.00 164.57 ? 247 ASN F CG 1 +ATOM 11345 O OD1 . ASN F 1 247 ? 80.502 -32.127 72.159 1.00 157.12 ? 247 ASN F OD1 1 +ATOM 11346 N ND2 . ASN F 1 247 ? 81.837 -31.187 73.710 1.00 181.61 ? 247 ASN F ND2 1 +ATOM 11347 N N . ASP F 1 248 ? 83.322 -34.460 71.540 1.00 155.19 ? 248 ASP F N 1 +ATOM 11348 C CA . ASP F 1 248 ? 83.112 -35.806 70.966 1.00 171.08 ? 248 ASP F CA 1 +ATOM 11349 C C . ASP F 1 248 ? 82.078 -35.795 69.838 1.00 174.08 ? 248 ASP F C 1 +ATOM 11350 O O . ASP F 1 248 ? 82.283 -36.375 68.764 1.00 177.65 ? 248 ASP F O 1 +ATOM 11351 C CB . ASP F 1 248 ? 82.632 -36.792 72.042 1.00 174.52 ? 248 ASP F CB 1 +ATOM 11352 C CG . ASP F 1 248 ? 83.714 -37.153 73.039 1.00 195.17 ? 248 ASP F CG 1 +ATOM 11353 O OD1 . ASP F 1 248 ? 84.890 -37.300 72.637 1.00 202.10 ? 248 ASP F OD1 1 +ATOM 11354 O OD2 . ASP F 1 248 ? 83.383 -37.306 74.233 1.00 231.42 ? 248 ASP F OD2 1 +ATOM 11355 N N . ILE F 1 249 ? 80.957 -35.138 70.106 1.00 163.29 ? 249 ILE F N 1 +ATOM 11356 C CA . ILE F 1 249 ? 79.852 -35.085 69.173 1.00 143.99 ? 249 ILE F CA 1 +ATOM 11357 C C . ILE F 1 249 ? 80.263 -34.308 67.919 1.00 134.53 ? 249 ILE F C 1 +ATOM 11358 O O . ILE F 1 249 ? 80.078 -34.778 66.786 1.00 159.36 ? 249 ILE F O 1 +ATOM 11359 C CB . ILE F 1 249 ? 78.620 -34.430 69.835 1.00 157.74 ? 249 ILE F CB 1 +ATOM 11360 C CG1 . ILE F 1 249 ? 78.144 -35.270 71.033 1.00 123.70 ? 249 ILE F CG1 1 +ATOM 11361 C CG2 . ILE F 1 249 ? 77.486 -34.293 68.828 1.00 206.69 ? 249 ILE F CG2 1 +ATOM 11362 C CD1 . ILE F 1 249 ? 77.282 -34.515 72.027 1.00 97.90 ? 249 ILE F CD1 1 +ATOM 11363 N N . LEU F 1 250 ? 80.827 -33.121 68.127 1.00 123.92 ? 250 LEU F N 1 +ATOM 11364 C CA . LEU F 1 250 ? 81.221 -32.250 67.019 1.00 140.48 ? 250 LEU F CA 1 +ATOM 11365 C C . LEU F 1 250 ? 82.246 -32.897 66.081 1.00 154.95 ? 250 LEU F C 1 +ATOM 11366 O O . LEU F 1 250 ? 82.172 -32.722 64.858 1.00 132.01 ? 250 LEU F O 1 +ATOM 11367 C CB . LEU F 1 250 ? 81.774 -30.927 67.544 1.00 127.35 ? 250 LEU F CB 1 +ATOM 11368 C CG . LEU F 1 250 ? 80.714 -29.909 67.971 1.00 136.28 ? 250 LEU F CG 1 +ATOM 11369 C CD1 . LEU F 1 250 ? 81.327 -28.750 68.736 1.00 148.34 ? 250 LEU F CD1 1 +ATOM 11370 C CD2 . LEU F 1 250 ? 79.970 -29.384 66.755 1.00 158.32 ? 250 LEU F CD2 1 +ATOM 11371 N N . VAL F 1 251 ? 83.182 -33.650 66.653 1.00 169.94 ? 251 VAL F N 1 +ATOM 11372 C CA . VAL F 1 251 ? 84.188 -34.351 65.847 1.00 164.62 ? 251 VAL F CA 1 +ATOM 11373 C C . VAL F 1 251 ? 83.614 -35.603 65.181 1.00 150.96 ? 251 VAL F C 1 +ATOM 11374 O O . VAL F 1 251 ? 84.118 -36.049 64.148 1.00 142.67 ? 251 VAL F O 1 +ATOM 11375 C CB . VAL F 1 251 ? 85.441 -34.732 66.671 1.00 146.71 ? 251 VAL F CB 1 +ATOM 11376 C CG1 . VAL F 1 251 ? 86.031 -33.497 67.345 1.00 137.44 ? 251 VAL F CG1 1 +ATOM 11377 C CG2 . VAL F 1 251 ? 85.126 -35.828 67.687 1.00 133.40 ? 251 VAL F CG2 1 +ATOM 11378 N N . LYS F 1 252 ? 82.571 -36.168 65.779 1.00 130.75 ? 252 LYS F N 1 +ATOM 11379 C CA . LYS F 1 252 ? 81.875 -37.303 65.185 1.00 131.57 ? 252 LYS F CA 1 +ATOM 11380 C C . LYS F 1 252 ? 81.164 -36.891 63.885 1.00 143.77 ? 252 LYS F C 1 +ATOM 11381 O O . LYS F 1 252 ? 81.303 -37.554 62.849 1.00 141.60 ? 252 LYS F O 1 +ATOM 11382 C CB . LYS F 1 252 ? 80.881 -37.862 66.203 1.00 140.51 ? 252 LYS F CB 1 +ATOM 11383 C CG . LYS F 1 252 ? 80.050 -39.040 65.723 1.00 138.94 ? 252 LYS F CG 1 +ATOM 11384 C CD . LYS F 1 252 ? 79.081 -39.484 66.817 1.00 129.03 ? 252 LYS F CD 1 +ATOM 11385 C CE . LYS F 1 252 ? 77.670 -39.680 66.275 1.00 121.85 ? 252 LYS F CE 1 +ATOM 11386 N NZ . LYS F 1 252 ? 76.668 -39.857 67.354 1.00 130.43 ? 252 LYS F NZ 1 +ATOM 11387 N N . TYR F 1 253 ? 80.461 -35.757 63.927 1.00 158.88 ? 253 TYR F N 1 +ATOM 11388 C CA . TYR F 1 253 ? 79.730 -35.239 62.756 1.00 144.05 ? 253 TYR F CA 1 +ATOM 11389 C C . TYR F 1 253 ? 80.668 -34.572 61.759 1.00 168.92 ? 253 TYR F C 1 +ATOM 11390 O O . TYR F 1 253 ? 80.441 -34.636 60.548 1.00 148.76 ? 253 TYR F O 1 +ATOM 11391 C CB . TYR F 1 253 ? 78.624 -34.269 63.182 1.00 123.08 ? 253 TYR F CB 1 +ATOM 11392 C CG . TYR F 1 253 ? 77.469 -34.998 63.854 1.00 147.58 ? 253 TYR F CG 1 +ATOM 11393 C CD1 . TYR F 1 253 ? 76.461 -35.601 63.099 1.00 136.19 ? 253 TYR F CD1 1 +ATOM 11394 C CD2 . TYR F 1 253 ? 77.424 -35.155 65.247 1.00 154.21 ? 253 TYR F CD2 1 +ATOM 11395 C CE1 . TYR F 1 253 ? 75.438 -36.308 63.717 1.00 132.94 ? 253 TYR F CE1 1 +ATOM 11396 C CE2 . TYR F 1 253 ? 76.395 -35.861 65.874 1.00 110.53 ? 253 TYR F CE2 1 +ATOM 11397 C CZ . TYR F 1 253 ? 75.417 -36.446 65.107 1.00 116.50 ? 253 TYR F CZ 1 +ATOM 11398 O OH . TYR F 1 253 ? 74.362 -37.084 65.698 1.00 93.21 ? 253 TYR F OH 1 +ATOM 11399 N N . ARG F 1 254 ? 81.742 -33.974 62.275 1.00 172.85 ? 254 ARG F N 1 +ATOM 11400 C CA . ARG F 1 254 ? 82.849 -33.505 61.435 1.00 146.88 ? 254 ARG F CA 1 +ATOM 11401 C C . ARG F 1 254 ? 83.458 -34.659 60.625 1.00 124.90 ? 254 ARG F C 1 +ATOM 11402 O O . ARG F 1 254 ? 83.746 -34.505 59.436 1.00 97.87 ? 254 ARG F O 1 +ATOM 11403 C CB . ARG F 1 254 ? 83.946 -32.872 62.296 1.00 155.60 ? 254 ARG F CB 1 +ATOM 11404 C CG . ARG F 1 254 ? 85.065 -32.248 61.479 1.00 179.27 ? 254 ARG F CG 1 +ATOM 11405 C CD . ARG F 1 254 ? 85.927 -31.288 62.284 1.00 167.09 ? 254 ARG F CD 1 +ATOM 11406 N NE . ARG F 1 254 ? 85.211 -30.097 62.728 1.00 175.63 ? 254 ARG F NE 1 +ATOM 11407 C CZ . ARG F 1 254 ? 84.825 -29.854 63.976 1.00 172.62 ? 254 ARG F CZ 1 +ATOM 11408 N NH1 . ARG F 1 254 ? 85.076 -30.717 64.946 1.00 168.02 ? 254 ARG F NH1 1 +ATOM 11409 N NH2 . ARG F 1 254 ? 84.169 -28.729 64.254 1.00 179.23 ? 254 ARG F NH2 1 +ATOM 11410 N N . HIS F 1 255 ? 83.602 -35.818 61.275 1.00 108.12 ? 255 HIS F N 1 +ATOM 11411 C CA . HIS F 1 255 ? 84.113 -37.018 60.624 1.00 124.47 ? 255 HIS F CA 1 +ATOM 11412 C C . HIS F 1 255 ? 83.175 -37.585 59.546 1.00 159.47 ? 255 HIS F C 1 +ATOM 11413 O O . HIS F 1 255 ? 83.636 -38.114 58.535 1.00 193.15 ? 255 HIS F O 1 +ATOM 11414 C CB . HIS F 1 255 ? 84.434 -38.103 61.662 1.00 151.98 ? 255 HIS F CB 1 +ATOM 11415 C CG . HIS F 1 255 ? 85.899 -38.268 61.913 1.00 197.41 ? 255 HIS F CG 1 +ATOM 11416 N ND1 . HIS F 1 255 ? 86.633 -37.357 62.639 1.00 220.59 ? 255 HIS F ND1 1 +ATOM 11417 C CD2 . HIS F 1 255 ? 86.778 -39.207 61.487 1.00 213.73 ? 255 HIS F CD2 1 +ATOM 11418 C CE1 . HIS F 1 255 ? 87.897 -37.744 62.677 1.00 209.56 ? 255 HIS F CE1 1 +ATOM 11419 N NE2 . HIS F 1 255 ? 88.012 -38.861 61.983 1.00 209.34 ? 255 HIS F NE2 1 +ATOM 11420 N N . MET F 1 256 ? 81.863 -37.500 59.760 1.00 153.10 ? 256 MET F N 1 +ATOM 11421 C CA . MET F 1 256 ? 80.911 -38.014 58.769 1.00 112.43 ? 256 MET F CA 1 +ATOM 11422 C C . MET F 1 256 ? 80.968 -37.191 57.468 1.00 128.97 ? 256 MET F C 1 +ATOM 11423 O O . MET F 1 256 ? 80.607 -37.698 56.401 1.00 113.66 ? 256 MET F O 1 +ATOM 11424 C CB . MET F 1 256 ? 79.494 -38.057 59.358 1.00 131.81 ? 256 MET F CB 1 +ATOM 11425 C CG . MET F 1 256 ? 79.401 -38.828 60.673 1.00 150.58 ? 256 MET F CG 1 +ATOM 11426 S SD . MET F 1 256 ? 77.749 -39.380 61.153 1.00 181.45 ? 256 MET F SD 1 +ATOM 11427 C CE . MET F 1 256 ? 77.454 -40.632 59.902 1.00 179.54 ? 256 MET F CE 1 +ATOM 11428 N N . SER F 1 257 ? 81.413 -35.926 57.569 1.00 147.43 ? 257 SER F N 1 +ATOM 11429 C CA . SER F 1 257 ? 81.592 -35.030 56.398 1.00 117.58 ? 257 SER F CA 1 +ATOM 11430 C C . SER F 1 257 ? 82.838 -35.355 55.579 1.00 107.49 ? 257 SER F C 1 +ATOM 11431 O O . SER F 1 257 ? 82.815 -36.242 54.735 1.00 67.13 ? 257 SER F O 1 +ATOM 11432 C CB . SER F 1 257 ? 81.673 -33.565 56.845 1.00 90.24 ? 257 SER F CB 1 +ATOM 11433 O OG . SER F 1 257 ? 80.694 -33.282 57.833 1.00 67.61 ? 257 SER F OG 1 +ATOM 11434 N N . LEU G 1 2 ? 56.382 -54.429 76.312 1.00 123.50 ? 2 LEU G N 1 +ATOM 11435 C CA . LEU G 1 2 ? 56.639 -54.340 74.831 1.00 141.09 ? 2 LEU G CA 1 +ATOM 11436 C C . LEU G 1 2 ? 55.311 -54.164 74.049 1.00 162.18 ? 2 LEU G C 1 +ATOM 11437 O O . LEU G 1 2 ? 54.835 -55.080 73.347 1.00 144.47 ? 2 LEU G O 1 +ATOM 11438 C CB . LEU G 1 2 ? 57.437 -55.556 74.338 1.00 138.84 ? 2 LEU G CB 1 +ATOM 11439 C CG . LEU G 1 2 ? 58.853 -55.814 74.915 1.00 136.44 ? 2 LEU G CG 1 +ATOM 11440 C CD1 . LEU G 1 2 ? 59.427 -57.086 74.300 1.00 128.56 ? 2 LEU G CD1 1 +ATOM 11441 C CD2 . LEU G 1 2 ? 59.833 -54.648 74.740 1.00 117.20 ? 2 LEU G CD2 1 +ATOM 11442 N N . THR G 1 3 ? 54.656 -53.037 74.341 1.00 192.06 ? 3 THR G N 1 +ATOM 11443 C CA . THR G 1 3 ? 53.540 -52.476 73.558 1.00 166.90 ? 3 THR G CA 1 +ATOM 11444 C C . THR G 1 3 ? 53.650 -50.931 73.490 1.00 134.21 ? 3 THR G C 1 +ATOM 11445 O O . THR G 1 3 ? 52.840 -50.249 72.863 1.00 81.39 ? 3 THR G O 1 +ATOM 11446 C CB . THR G 1 3 ? 52.161 -52.836 74.165 1.00 158.78 ? 3 THR G CB 1 +ATOM 11447 O OG1 . THR G 1 3 ? 51.992 -52.156 75.422 1.00 136.98 ? 3 THR G OG1 1 +ATOM 11448 C CG2 . THR G 1 3 ? 51.999 -54.359 74.326 1.00 120.11 ? 3 THR G CG2 1 +ATOM 11449 N N . ALA G 1 4 ? 54.636 -50.390 74.188 1.00 129.53 ? 4 ALA G N 1 +ATOM 11450 C CA . ALA G 1 4 ? 55.180 -49.079 73.861 1.00 120.09 ? 4 ALA G CA 1 +ATOM 11451 C C . ALA G 1 4 ? 56.011 -49.197 72.554 1.00 92.66 ? 4 ALA G C 1 +ATOM 11452 O O . ALA G 1 4 ? 56.022 -50.233 71.908 1.00 71.29 ? 4 ALA G O 1 +ATOM 11453 C CB . ALA G 1 4 ? 56.006 -48.554 75.042 1.00 121.46 ? 4 ALA G CB 1 +ATOM 11454 N N . PRO G 1 5 ? 56.681 -48.127 72.131 1.00 84.68 ? 5 PRO G N 1 +ATOM 11455 C CA . PRO G 1 5 ? 57.159 -48.279 70.768 1.00 76.33 ? 5 PRO G CA 1 +ATOM 11456 C C . PRO G 1 5 ? 58.405 -49.176 70.669 1.00 80.19 ? 5 PRO G C 1 +ATOM 11457 O O . PRO G 1 5 ? 59.070 -49.429 71.667 1.00 75.26 ? 5 PRO G O 1 +ATOM 11458 C CB . PRO G 1 5 ? 57.442 -46.814 70.349 1.00 90.55 ? 5 PRO G CB 1 +ATOM 11459 C CG . PRO G 1 5 ? 57.740 -46.066 71.628 1.00 93.51 ? 5 PRO G CG 1 +ATOM 11460 C CD . PRO G 1 5 ? 57.158 -46.874 72.772 1.00 100.58 ? 5 PRO G CD 1 +ATOM 11461 N N . PRO G 1 6 ? 58.818 -49.509 69.451 1.00 73.72 ? 6 PRO G N 1 +ATOM 11462 C CA . PRO G 1 6 ? 60.194 -49.951 69.160 1.00 70.95 ? 6 PRO G CA 1 +ATOM 11463 C C . PRO G 1 6 ? 61.271 -48.842 69.112 1.00 70.29 ? 6 PRO G C 1 +ATOM 11464 O O . PRO G 1 6 ? 60.985 -47.714 68.787 1.00 63.45 ? 6 PRO G O 1 +ATOM 11465 C CB . PRO G 1 6 ? 60.071 -50.618 67.796 1.00 70.80 ? 6 PRO G CB 1 +ATOM 11466 C CG . PRO G 1 6 ? 58.824 -50.080 67.195 1.00 80.61 ? 6 PRO G CG 1 +ATOM 11467 C CD . PRO G 1 6 ? 57.961 -49.475 68.265 1.00 70.24 ? 6 PRO G CD 1 +ATOM 11468 N N . LYS G 1 7 ? 62.513 -49.188 69.418 1.00 98.25 ? 7 LYS G N 1 +ATOM 11469 C CA . LYS G 1 7 ? 63.617 -48.213 69.446 1.00 127.80 ? 7 LYS G CA 1 +ATOM 11470 C C . LYS G 1 7 ? 64.412 -48.190 68.136 1.00 129.07 ? 7 LYS G C 1 +ATOM 11471 O O . LYS G 1 7 ? 64.222 -49.063 67.281 1.00 98.11 ? 7 LYS G O 1 +ATOM 11472 C CB . LYS G 1 7 ? 64.554 -48.496 70.634 1.00 158.78 ? 7 LYS G CB 1 +ATOM 11473 C CG . LYS G 1 7 ? 63.946 -48.215 71.993 1.00 179.90 ? 7 LYS G CG 1 +ATOM 11474 C CD . LYS G 1 7 ? 63.558 -49.484 72.756 1.00 170.53 ? 7 LYS G CD 1 +ATOM 11475 C CE . LYS G 1 7 ? 63.254 -49.164 74.208 1.00 156.16 ? 7 LYS G CE 1 +ATOM 11476 N NZ . LYS G 1 7 ? 62.267 -50.107 74.792 1.00 137.06 ? 7 LYS G NZ 1 +ATOM 11477 N N . GLU G 1 8 ? 65.322 -47.216 68.025 1.00 131.53 ? 8 GLU G N 1 +ATOM 11478 C CA . GLU G 1 8 ? 66.011 -46.908 66.769 1.00 149.35 ? 8 GLU G CA 1 +ATOM 11479 C C . GLU G 1 8 ? 66.850 -48.069 66.232 1.00 125.94 ? 8 GLU G C 1 +ATOM 11480 O O . GLU G 1 8 ? 67.843 -48.458 66.832 1.00 126.97 ? 8 GLU G O 1 +ATOM 11481 C CB . GLU G 1 8 ? 66.878 -45.596 66.879 1.00 186.39 ? 8 GLU G CB 1 +ATOM 11482 C CG . GLU G 1 8 ? 68.247 -45.699 67.528 1.00 203.33 ? 8 GLU G CG 1 +ATOM 11483 C CD . GLU G 1 8 ? 69.057 -44.401 67.456 1.00 202.32 ? 8 GLU G CD 1 +ATOM 11484 O OE1 . GLU G 1 8 ? 69.245 -43.834 66.364 1.00 191.38 ? 8 GLU G OE1 1 +ATOM 11485 O OE2 . GLU G 1 8 ? 69.562 -43.952 68.490 1.00 167.07 ? 8 GLU G OE2 1 +ATOM 11486 N N . ALA G 1 9 ? 66.454 -48.574 65.065 1.00 121.95 ? 9 ALA G N 1 +ATOM 11487 C CA . ALA G 1 9 ? 67.261 -49.471 64.259 1.00 106.32 ? 9 ALA G CA 1 +ATOM 11488 C C . ALA G 1 9 ? 67.958 -48.720 63.101 1.00 113.82 ? 9 ALA G C 1 +ATOM 11489 O O . ALA G 1 9 ? 67.314 -48.298 62.131 1.00 134.99 ? 9 ALA G O 1 +ATOM 11490 C CB . ALA G 1 9 ? 66.380 -50.577 63.702 1.00 98.35 ? 9 ALA G CB 1 +ATOM 11491 N N . ALA G 1 10 ? 69.280 -48.598 63.212 1.00 113.53 ? 10 ALA G N 1 +ATOM 11492 C CA . ALA G 1 10 ? 70.138 -47.850 62.271 1.00 114.90 ? 10 ALA G CA 1 +ATOM 11493 C C . ALA G 1 10 ? 70.181 -46.379 62.638 1.00 113.73 ? 10 ALA G C 1 +ATOM 11494 O O . ALA G 1 10 ? 69.293 -45.888 63.346 1.00 77.09 ? 10 ALA G O 1 +ATOM 11495 C CB . ALA G 1 10 ? 69.707 -48.037 60.813 1.00 125.76 ? 10 ALA G CB 1 +ATOM 11496 N N . ARG G 1 11 ? 71.221 -45.690 62.153 1.00 131.33 ? 11 ARG G N 1 +ATOM 11497 C CA . ARG G 1 11 ? 71.396 -44.254 62.414 1.00 132.84 ? 11 ARG G CA 1 +ATOM 11498 C C . ARG G 1 11 ? 71.186 -43.398 61.148 1.00 113.71 ? 11 ARG G C 1 +ATOM 11499 O O . ARG G 1 11 ? 71.352 -43.861 60.002 1.00 123.42 ? 11 ARG G O 1 +ATOM 11500 C CB . ARG G 1 11 ? 72.703 -43.942 63.142 1.00 124.68 ? 11 ARG G CB 1 +ATOM 11501 C CG . ARG G 1 11 ? 72.657 -44.199 64.648 1.00 139.02 ? 11 ARG G CG 1 +ATOM 11502 C CD . ARG G 1 11 ? 74.014 -44.212 65.311 1.00 159.38 ? 11 ARG G CD 1 +ATOM 11503 N NE . ARG G 1 11 ? 73.861 -44.212 66.765 1.00 178.27 ? 11 ARG G NE 1 +ATOM 11504 C CZ . ARG G 1 11 ? 74.877 -44.315 67.616 1.00 199.58 ? 11 ARG G CZ 1 +ATOM 11505 N NH1 . ARG G 1 11 ? 76.120 -44.390 67.161 1.00 215.34 ? 11 ARG G NH1 1 +ATOM 11506 N NH2 . ARG G 1 11 ? 74.651 -44.326 68.921 1.00 189.87 ? 11 ARG G NH2 1 +ATOM 11507 N N . PRO G 1 12 ? 70.698 -42.170 61.337 1.00 97.79 ? 12 PRO G N 1 +ATOM 11508 C CA . PRO G 1 12 ? 70.705 -41.261 60.217 1.00 101.43 ? 12 PRO G CA 1 +ATOM 11509 C C . PRO G 1 12 ? 72.158 -40.988 59.794 1.00 99.62 ? 12 PRO G C 1 +ATOM 11510 O O . PRO G 1 12 ? 72.934 -40.419 60.557 1.00 140.27 ? 12 PRO G O 1 +ATOM 11511 C CB . PRO G 1 12 ? 70.033 -39.977 60.776 1.00 106.48 ? 12 PRO G CB 1 +ATOM 11512 C CG . PRO G 1 12 ? 69.393 -40.362 62.066 1.00 94.25 ? 12 PRO G CG 1 +ATOM 11513 C CD . PRO G 1 12 ? 70.222 -41.519 62.571 1.00 116.41 ? 12 PRO G CD 1 +ATOM 11514 N N . THR G 1 13 ? 72.503 -41.393 58.589 1.00 80.92 ? 13 THR G N 1 +ATOM 11515 C CA . THR G 1 13 ? 73.702 -40.916 57.932 1.00 85.50 ? 13 THR G CA 1 +ATOM 11516 C C . THR G 1 13 ? 73.395 -39.674 57.080 1.00 96.45 ? 13 THR G C 1 +ATOM 11517 O O . THR G 1 13 ? 72.248 -39.452 56.707 1.00 158.25 ? 13 THR G O 1 +ATOM 11518 C CB . THR G 1 13 ? 74.253 -42.030 57.032 1.00 93.63 ? 13 THR G CB 1 +ATOM 11519 O OG1 . THR G 1 13 ? 75.549 -41.668 56.546 1.00 87.70 ? 13 THR G OG1 1 +ATOM 11520 C CG2 . THR G 1 13 ? 73.294 -42.336 55.828 1.00 91.07 ? 13 THR G CG2 1 +ATOM 11521 N N . LEU G 1 14 ? 74.403 -38.897 56.701 1.00 105.30 ? 14 LEU G N 1 +ATOM 11522 C CA . LEU G 1 14 ? 74.164 -37.907 55.641 1.00 106.18 ? 14 LEU G CA 1 +ATOM 11523 C C . LEU G 1 14 ? 74.048 -38.620 54.276 1.00 106.45 ? 14 LEU G C 1 +ATOM 11524 O O . LEU G 1 14 ? 74.436 -39.770 54.158 1.00 93.51 ? 14 LEU G O 1 +ATOM 11525 C CB . LEU G 1 14 ? 75.188 -36.773 55.634 1.00 114.16 ? 14 LEU G CB 1 +ATOM 11526 C CG . LEU G 1 14 ? 76.666 -37.127 55.564 1.00 121.32 ? 14 LEU G CG 1 +ATOM 11527 C CD1 . LEU G 1 14 ? 77.437 -36.067 54.786 1.00 140.04 ? 14 LEU G CD1 1 +ATOM 11528 C CD2 . LEU G 1 14 ? 77.202 -37.236 56.971 1.00 95.48 ? 14 LEU G CD2 1 +ATOM 11529 N N . MET G 1 15 ? 73.416 -37.989 53.289 1.00 132.14 ? 15 MET G N 1 +ATOM 11530 C CA . MET G 1 15 ? 72.746 -38.741 52.204 1.00 137.64 ? 15 MET G CA 1 +ATOM 11531 C C . MET G 1 15 ? 73.765 -39.384 51.263 1.00 120.60 ? 15 MET G C 1 +ATOM 11532 O O . MET G 1 15 ? 74.636 -38.707 50.732 1.00 80.64 ? 15 MET G O 1 +ATOM 11533 C CB . MET G 1 15 ? 71.765 -37.865 51.408 1.00 126.24 ? 15 MET G CB 1 +ATOM 11534 C CG . MET G 1 15 ? 70.610 -38.662 50.827 1.00 99.51 ? 15 MET G CG 1 +ATOM 11535 S SD . MET G 1 15 ? 70.011 -38.322 49.181 1.00 110.96 ? 15 MET G SD 1 +ATOM 11536 C CE . MET G 1 15 ? 71.225 -37.260 48.373 1.00 83.20 ? 15 MET G CE 1 +ATOM 11537 N N . PRO G 1 16 ? 73.688 -40.716 51.118 1.00 104.99 ? 16 PRO G N 1 +ATOM 11538 C CA . PRO G 1 16 ? 74.699 -41.524 50.433 1.00 108.31 ? 16 PRO G CA 1 +ATOM 11539 C C . PRO G 1 16 ? 74.827 -41.210 48.948 1.00 94.80 ? 16 PRO G C 1 +ATOM 11540 O O . PRO G 1 16 ? 74.328 -41.946 48.100 1.00 122.67 ? 16 PRO G O 1 +ATOM 11541 C CB . PRO G 1 16 ? 74.213 -42.964 50.664 1.00 121.20 ? 16 PRO G CB 1 +ATOM 11542 C CG . PRO G 1 16 ? 72.755 -42.822 50.917 1.00 126.53 ? 16 PRO G CG 1 +ATOM 11543 C CD . PRO G 1 16 ? 72.614 -41.551 51.683 1.00 99.24 ? 16 PRO G CD 1 +ATOM 11544 N N . ARG G 1 17 ? 75.585 -40.173 48.640 1.00 118.76 ? 17 ARG G N 1 +ATOM 11545 C CA . ARG G 1 17 ? 75.961 -39.885 47.264 1.00 151.73 ? 17 ARG G CA 1 +ATOM 11546 C C . ARG G 1 17 ? 77.210 -40.693 46.866 1.00 119.19 ? 17 ARG G C 1 +ATOM 11547 O O . ARG G 1 17 ? 78.095 -40.857 47.692 1.00 127.72 ? 17 ARG G O 1 +ATOM 11548 C CB . ARG G 1 17 ? 76.177 -38.368 47.112 1.00 154.66 ? 17 ARG G CB 1 +ATOM 11549 C CG . ARG G 1 17 ? 74.889 -37.604 46.824 1.00 155.58 ? 17 ARG G CG 1 +ATOM 11550 C CD . ARG G 1 17 ? 75.006 -36.119 47.094 1.00 155.25 ? 17 ARG G CD 1 +ATOM 11551 N NE . ARG G 1 17 ? 74.926 -35.823 48.519 1.00 139.68 ? 17 ARG G NE 1 +ATOM 11552 C CZ . ARG G 1 17 ? 75.145 -34.619 49.038 1.00 93.17 ? 17 ARG G CZ 1 +ATOM 11553 N NH1 . ARG G 1 17 ? 75.471 -33.604 48.232 1.00 75.12 ? 17 ARG G NH1 1 +ATOM 11554 N NH2 . ARG G 1 17 ? 75.033 -34.428 50.350 1.00 62.68 ? 17 ARG G NH2 1 +ATOM 11555 N N . ALA G 1 18 ? 77.304 -41.122 45.603 1.00 83.29 ? 18 ALA G N 1 +ATOM 11556 C CA . ALA G 1 18 ? 78.466 -41.849 45.137 1.00 93.31 ? 18 ALA G CA 1 +ATOM 11557 C C . ALA G 1 18 ? 79.359 -41.064 44.135 1.00 110.99 ? 18 ALA G C 1 +ATOM 11558 O O . ALA G 1 18 ? 80.007 -40.065 44.511 1.00 150.57 ? 18 ALA G O 1 +ATOM 11559 C CB . ALA G 1 18 ? 78.035 -43.171 44.558 1.00 96.29 ? 18 ALA G CB 1 +ATOM 11560 N N . GLN G 1 19 ? 79.524 -41.591 42.923 1.00 123.45 ? 19 GLN G N 1 +ATOM 11561 C CA . GLN G 1 19 ? 80.702 -41.264 42.093 1.00 171.23 ? 19 GLN G CA 1 +ATOM 11562 C C . GLN G 1 19 ? 80.603 -39.848 41.554 1.00 165.09 ? 19 GLN G C 1 +ATOM 11563 O O . GLN G 1 19 ? 81.559 -39.048 41.632 1.00 194.73 ? 19 GLN G O 1 +ATOM 11564 C CB . GLN G 1 19 ? 80.831 -42.248 40.919 1.00 207.77 ? 19 GLN G CB 1 +ATOM 11565 C CG . GLN G 1 19 ? 82.074 -42.052 40.056 1.00 207.23 ? 19 GLN G CG 1 +ATOM 11566 C CD . GLN G 1 19 ? 83.351 -42.076 40.879 1.00 213.48 ? 19 GLN G CD 1 +ATOM 11567 O OE1 . GLN G 1 19 ? 83.736 -43.115 41.420 1.00 226.36 ? 19 GLN G OE1 1 +ATOM 11568 N NE2 . GLN G 1 19 ? 84.019 -40.933 40.975 1.00 213.15 ? 19 GLN G NE2 1 +ATOM 11569 N N . SER G 1 20 ? 79.439 -39.560 40.988 1.00 117.48 ? 20 SER G N 1 +ATOM 11570 C CA . SER G 1 20 ? 79.111 -38.235 40.535 1.00 110.02 ? 20 SER G CA 1 +ATOM 11571 C C . SER G 1 20 ? 79.555 -37.185 41.572 1.00 123.08 ? 20 SER G C 1 +ATOM 11572 O O . SER G 1 20 ? 80.189 -36.181 41.229 1.00 100.45 ? 20 SER G O 1 +ATOM 11573 C CB . SER G 1 20 ? 77.600 -38.174 40.302 1.00 125.60 ? 20 SER G CB 1 +ATOM 11574 O OG . SER G 1 20 ? 77.165 -39.250 39.480 1.00 84.87 ? 20 SER G OG 1 +ATOM 11575 N N . TYR G 1 21 ? 79.169 -37.399 42.832 1.00 130.92 ? 21 TYR G N 1 +ATOM 11576 C CA . TYR G 1 21 ? 79.521 -36.492 43.931 1.00 134.77 ? 21 TYR G CA 1 +ATOM 11577 C C . TYR G 1 21 ? 81.035 -36.299 44.030 1.00 128.73 ? 21 TYR G C 1 +ATOM 11578 O O . TYR G 1 21 ? 81.520 -35.175 44.171 1.00 98.09 ? 21 TYR G O 1 +ATOM 11579 C CB . TYR G 1 21 ? 78.963 -37.034 45.265 1.00 161.64 ? 21 TYR G CB 1 +ATOM 11580 C CG . TYR G 1 21 ? 79.252 -36.144 46.460 1.00 201.10 ? 21 TYR G CG 1 +ATOM 11581 C CD1 . TYR G 1 21 ? 78.547 -34.956 46.655 1.00 203.24 ? 21 TYR G CD1 1 +ATOM 11582 C CD2 . TYR G 1 21 ? 80.262 -36.466 47.366 1.00 203.55 ? 21 TYR G CD2 1 +ATOM 11583 C CE1 . TYR G 1 21 ? 78.826 -34.119 47.719 1.00 190.09 ? 21 TYR G CE1 1 +ATOM 11584 C CE2 . TYR G 1 21 ? 80.549 -35.628 48.438 1.00 178.74 ? 21 TYR G CE2 1 +ATOM 11585 C CZ . TYR G 1 21 ? 79.824 -34.454 48.610 1.00 156.49 ? 21 TYR G CZ 1 +ATOM 11586 O OH . TYR G 1 21 ? 80.050 -33.621 49.679 1.00 85.80 ? 21 TYR G OH 1 +ATOM 11587 N N . LYS G 1 22 ? 81.766 -37.416 44.051 1.00 173.54 ? 22 LYS G N 1 +ATOM 11588 C CA . LYS G 1 22 ? 83.221 -37.407 44.254 1.00 165.73 ? 22 LYS G CA 1 +ATOM 11589 C C . LYS G 1 22 ? 83.927 -36.625 43.150 1.00 166.97 ? 22 LYS G C 1 +ATOM 11590 O O . LYS G 1 22 ? 84.849 -35.853 43.416 1.00 158.92 ? 22 LYS G O 1 +ATOM 11591 C CB . LYS G 1 22 ? 83.762 -38.842 44.275 1.00 153.73 ? 22 LYS G CB 1 +ATOM 11592 C CG . LYS G 1 22 ? 83.776 -39.498 45.620 1.00 144.22 ? 22 LYS G CG 1 +ATOM 11593 C CD . LYS G 1 22 ? 85.195 -39.804 46.051 1.00 150.88 ? 22 LYS G CD 1 +ATOM 11594 C CE . LYS G 1 22 ? 86.374 -39.001 45.641 1.00 147.25 ? 22 LYS G CE 1 +ATOM 11595 N NZ . LYS G 1 22 ? 86.976 -38.624 46.926 1.00 124.91 ? 22 LYS G NZ 1 +ATOM 11596 N N . ASP G 1 23 ? 83.440 -36.781 41.919 1.00 159.14 ? 23 ASP G N 1 +ATOM 11597 C CA . ASP G 1 23 ? 83.908 -35.979 40.786 1.00 155.98 ? 23 ASP G CA 1 +ATOM 11598 C C . ASP G 1 23 ? 83.557 -34.496 40.959 1.00 154.74 ? 23 ASP G C 1 +ATOM 11599 O O . ASP G 1 23 ? 84.399 -33.619 40.748 1.00 128.63 ? 23 ASP G O 1 +ATOM 11600 C CB . ASP G 1 23 ? 83.284 -36.484 39.482 1.00 164.24 ? 23 ASP G CB 1 +ATOM 11601 C CG . ASP G 1 23 ? 83.766 -37.850 39.100 1.00 151.57 ? 23 ASP G CG 1 +ATOM 11602 O OD1 . ASP G 1 23 ? 84.972 -38.101 39.266 1.00 116.18 ? 23 ASP G OD1 1 +ATOM 11603 O OD2 . ASP G 1 23 ? 82.929 -38.670 38.653 1.00 184.65 ? 23 ASP G OD2 1 +ATOM 11604 N N . LEU G 1 24 ? 82.313 -34.239 41.362 1.00 151.06 ? 24 LEU G N 1 +ATOM 11605 C CA . LEU G 1 24 ? 81.778 -32.882 41.472 1.00 157.42 ? 24 LEU G CA 1 +ATOM 11606 C C . LEU G 1 24 ? 82.501 -32.049 42.536 1.00 175.19 ? 24 LEU G C 1 +ATOM 11607 O O . LEU G 1 24 ? 82.711 -30.838 42.366 1.00 200.62 ? 24 LEU G O 1 +ATOM 11608 C CB . LEU G 1 24 ? 80.286 -32.952 41.810 1.00 157.19 ? 24 LEU G CB 1 +ATOM 11609 C CG . LEU G 1 24 ? 79.525 -31.630 41.956 1.00 166.95 ? 24 LEU G CG 1 +ATOM 11610 C CD1 . LEU G 1 24 ? 79.032 -31.127 40.604 1.00 185.29 ? 24 LEU G CD1 1 +ATOM 11611 C CD2 . LEU G 1 24 ? 78.357 -31.799 42.913 1.00 162.51 ? 24 LEU G CD2 1 +ATOM 11612 N N . THR G 1 25 ? 82.879 -32.702 43.634 1.00 198.22 ? 25 THR G N 1 +ATOM 11613 C CA . THR G 1 25 ? 83.569 -32.025 44.737 1.00 189.90 ? 25 THR G CA 1 +ATOM 11614 C C . THR G 1 25 ? 85.033 -31.688 44.411 1.00 170.19 ? 25 THR G C 1 +ATOM 11615 O O . THR G 1 25 ? 85.487 -30.563 44.645 1.00 104.85 ? 25 THR G O 1 +ATOM 11616 C CB . THR G 1 25 ? 83.517 -32.872 46.026 1.00 201.30 ? 25 THR G CB 1 +ATOM 11617 O OG1 . THR G 1 25 ? 83.880 -34.235 45.728 1.00 251.83 ? 25 THR G OG1 1 +ATOM 11618 C CG2 . THR G 1 25 ? 82.119 -32.828 46.620 1.00 166.00 ? 25 THR G CG2 1 +ATOM 11619 N N . HIS G 1 26 ? 85.756 -32.670 43.866 1.00 180.30 ? 26 HIS G N 1 +ATOM 11620 C CA . HIS G 1 26 ? 87.186 -32.533 43.560 1.00 159.46 ? 26 HIS G CA 1 +ATOM 11621 C C . HIS G 1 26 ? 87.401 -31.866 42.192 1.00 142.80 ? 26 HIS G C 1 +ATOM 11622 O O . HIS G 1 26 ? 88.317 -32.205 41.456 1.00 163.39 ? 26 HIS G O 1 +ATOM 11623 C CB . HIS G 1 26 ? 87.884 -33.912 43.629 1.00 153.44 ? 26 HIS G CB 1 +ATOM 11624 C CG . HIS G 1 26 ? 87.880 -34.524 45.002 1.00 172.90 ? 26 HIS G CG 1 +ATOM 11625 N ND1 . HIS G 1 26 ? 86.726 -34.968 45.611 1.00 174.43 ? 26 HIS G ND1 1 +ATOM 11626 C CD2 . HIS G 1 26 ? 88.873 -34.696 45.912 1.00 167.51 ? 26 HIS G CD2 1 +ATOM 11627 C CE1 . HIS G 1 26 ? 87.008 -35.387 46.833 1.00 160.19 ? 26 HIS G CE1 1 +ATOM 11628 N NE2 . HIS G 1 26 ? 88.306 -35.245 47.037 1.00 144.71 ? 26 HIS G NE2 1 +ATOM 11629 N N . LEU G 1 27 ? 86.543 -30.916 41.848 1.00 133.53 ? 27 LEU G N 1 +ATOM 11630 C CA . LEU G 1 27 ? 86.721 -30.146 40.623 1.00 130.05 ? 27 LEU G CA 1 +ATOM 11631 C C . LEU G 1 27 ? 87.607 -28.937 40.909 1.00 106.50 ? 27 LEU G C 1 +ATOM 11632 O O . LEU G 1 27 ? 87.401 -28.235 41.898 1.00 101.51 ? 27 LEU G O 1 +ATOM 11633 C CB . LEU G 1 27 ? 85.362 -29.686 40.062 1.00 159.91 ? 27 LEU G CB 1 +ATOM 11634 C CG . LEU G 1 27 ? 84.661 -30.675 39.123 1.00 165.79 ? 27 LEU G CG 1 +ATOM 11635 C CD1 . LEU G 1 27 ? 83.215 -30.276 38.885 1.00 159.70 ? 27 LEU G CD1 1 +ATOM 11636 C CD2 . LEU G 1 27 ? 85.407 -30.780 37.797 1.00 184.32 ? 27 LEU G CD2 1 +ATOM 11637 N N . PRO G 1 28 ? 88.557 -28.652 40.011 1.00 103.96 ? 28 PRO G N 1 +ATOM 11638 C CA . PRO G 1 28 ? 89.456 -27.499 40.168 1.00 109.24 ? 28 PRO G CA 1 +ATOM 11639 C C . PRO G 1 28 ? 88.706 -26.188 40.224 1.00 90.54 ? 28 PRO G C 1 +ATOM 11640 O O . PRO G 1 28 ? 87.886 -25.936 39.360 1.00 120.05 ? 28 PRO G O 1 +ATOM 11641 C CB . PRO G 1 28 ? 90.325 -27.553 38.907 1.00 123.97 ? 28 PRO G CB 1 +ATOM 11642 C CG . PRO G 1 28 ? 89.510 -28.318 37.909 1.00 119.77 ? 28 PRO G CG 1 +ATOM 11643 C CD . PRO G 1 28 ? 88.743 -29.326 38.713 1.00 118.89 ? 28 PRO G CD 1 +ATOM 11644 N N . ALA G 1 29 ? 88.969 -25.376 41.244 1.00 88.22 ? 29 ALA G N 1 +ATOM 11645 C CA . ALA G 1 29 ? 88.138 -24.202 41.540 1.00 82.86 ? 29 ALA G CA 1 +ATOM 11646 C C . ALA G 1 29 ? 88.324 -23.060 40.491 1.00 92.02 ? 29 ALA G C 1 +ATOM 11647 O O . ALA G 1 29 ? 89.392 -22.901 39.901 1.00 58.19 ? 29 ALA G O 1 +ATOM 11648 C CB . ALA G 1 29 ? 88.394 -23.699 42.963 1.00 56.92 ? 29 ALA G CB 1 +ATOM 11649 N N . PRO G 1 30 ? 87.248 -22.298 40.214 1.00 101.52 ? 30 PRO G N 1 +ATOM 11650 C CA . PRO G 1 30 ? 87.280 -21.144 39.310 1.00 97.95 ? 30 PRO G CA 1 +ATOM 11651 C C . PRO G 1 30 ? 87.888 -19.922 39.989 1.00 89.57 ? 30 PRO G C 1 +ATOM 11652 O O . PRO G 1 30 ? 88.220 -19.976 41.176 1.00 69.55 ? 30 PRO G O 1 +ATOM 11653 C CB . PRO G 1 30 ? 85.813 -20.867 39.057 1.00 118.39 ? 30 PRO G CB 1 +ATOM 11654 C CG . PRO G 1 30 ? 85.129 -21.323 40.307 1.00 127.37 ? 30 PRO G CG 1 +ATOM 11655 C CD . PRO G 1 30 ? 85.924 -22.479 40.836 1.00 106.86 ? 30 PRO G CD 1 +ATOM 11656 N N . THR G 1 31 ? 88.057 -18.841 39.231 1.00 97.13 ? 31 THR G N 1 +ATOM 11657 C CA . THR G 1 31 ? 88.707 -17.627 39.750 1.00 113.03 ? 31 THR G CA 1 +ATOM 11658 C C . THR G 1 31 ? 87.863 -16.970 40.839 1.00 129.40 ? 31 THR G C 1 +ATOM 11659 O O . THR G 1 31 ? 88.381 -16.238 41.681 1.00 173.81 ? 31 THR G O 1 +ATOM 11660 C CB . THR G 1 31 ? 89.055 -16.592 38.634 1.00 107.89 ? 31 THR G CB 1 +ATOM 11661 O OG1 . THR G 1 31 ? 87.907 -16.306 37.825 1.00 95.71 ? 31 THR G OG1 1 +ATOM 11662 C CG2 . THR G 1 31 ? 90.173 -17.111 37.737 1.00 120.75 ? 31 THR G CG2 1 +ATOM 11663 N N . GLY G 1 32 ? 86.554 -17.170 40.762 1.00 138.19 ? 32 GLY G N 1 +ATOM 11664 C CA . GLY G 1 32 ? 85.643 -16.761 41.823 1.00 147.62 ? 32 GLY G CA 1 +ATOM 11665 C C . GLY G 1 32 ? 84.390 -17.593 41.688 1.00 158.85 ? 32 GLY G C 1 +ATOM 11666 O O . GLY G 1 32 ? 84.073 -18.054 40.585 1.00 189.84 ? 32 GLY G O 1 +ATOM 11667 N N . LYS G 1 33 ? 83.671 -17.804 42.785 1.00 133.93 ? 33 LYS G N 1 +ATOM 11668 C CA . LYS G 1 33 ? 82.402 -18.509 42.679 1.00 115.31 ? 33 LYS G CA 1 +ATOM 11669 C C . LYS G 1 33 ? 81.373 -17.685 41.880 1.00 151.39 ? 33 LYS G C 1 +ATOM 11670 O O . LYS G 1 33 ? 81.416 -16.448 41.899 1.00 152.50 ? 33 LYS G O 1 +ATOM 11671 C CB . LYS G 1 33 ? 81.858 -18.874 44.051 1.00 94.68 ? 33 LYS G CB 1 +ATOM 11672 C CG . LYS G 1 33 ? 82.316 -20.218 44.565 1.00 99.32 ? 33 LYS G CG 1 +ATOM 11673 C CD . LYS G 1 33 ? 81.881 -20.451 46.004 1.00 96.53 ? 33 LYS G CD 1 +ATOM 11674 C CE . LYS G 1 33 ? 82.818 -21.410 46.704 1.00 93.74 ? 33 LYS G CE 1 +ATOM 11675 N NZ . LYS G 1 33 ? 82.516 -21.512 48.139 1.00 101.27 ? 33 LYS G NZ 1 +ATOM 11676 N N . ILE G 1 34 ? 80.449 -18.370 41.199 1.00 155.46 ? 34 ILE G N 1 +ATOM 11677 C CA . ILE G 1 34 ? 79.442 -17.702 40.374 1.00 127.29 ? 34 ILE G CA 1 +ATOM 11678 C C . ILE G 1 34 ? 78.071 -17.764 41.075 1.00 110.28 ? 34 ILE G C 1 +ATOM 11679 O O . ILE G 1 34 ? 77.798 -18.699 41.836 1.00 64.09 ? 34 ILE G O 1 +ATOM 11680 C CB . ILE G 1 34 ? 79.414 -18.299 38.953 1.00 119.29 ? 34 ILE G CB 1 +ATOM 11681 C CG1 . ILE G 1 34 ? 80.733 -17.998 38.239 1.00 126.67 ? 34 ILE G CG1 1 +ATOM 11682 C CG2 . ILE G 1 34 ? 78.296 -17.712 38.112 1.00 146.33 ? 34 ILE G CG2 1 +ATOM 11683 C CD1 . ILE G 1 34 ? 81.495 -19.249 37.866 1.00 171.06 ? 34 ILE G CD1 1 +ATOM 11684 N N . PHE G 1 35 ? 77.319 -16.655 40.972 1.00 113.16 ? 35 PHE G N 1 +ATOM 11685 C CA . PHE G 1 35 ? 76.009 -16.478 41.623 1.00 81.95 ? 35 PHE G CA 1 +ATOM 11686 C C . PHE G 1 35 ? 74.893 -17.074 40.784 1.00 67.17 ? 35 PHE G C 1 +ATOM 11687 O O . PHE G 1 35 ? 74.805 -16.750 39.615 1.00 56.55 ? 35 PHE G O 1 +ATOM 11688 C CB . PHE G 1 35 ? 75.707 -15.001 41.745 1.00 69.64 ? 35 PHE G CB 1 +ATOM 11689 C CG . PHE G 1 35 ? 76.254 -14.364 42.983 1.00 80.18 ? 35 PHE G CG 1 +ATOM 11690 C CD1 . PHE G 1 35 ? 76.121 -14.979 44.244 1.00 67.46 ? 35 PHE G CD1 1 +ATOM 11691 C CD2 . PHE G 1 35 ? 76.792 -13.088 42.917 1.00 83.04 ? 35 PHE G CD2 1 +ATOM 11692 C CE1 . PHE G 1 35 ? 76.592 -14.360 45.384 1.00 61.31 ? 35 PHE G CE1 1 +ATOM 11693 C CE2 . PHE G 1 35 ? 77.225 -12.449 44.066 1.00 80.88 ? 35 PHE G CE2 1 +ATOM 11694 C CZ . PHE G 1 35 ? 77.147 -13.094 45.297 1.00 70.72 ? 35 PHE G CZ 1 +ATOM 11695 N N . VAL G 1 36 ? 74.121 -18.006 41.350 1.00 52.21 ? 36 VAL G N 1 +ATOM 11696 C CA . VAL G 1 36 ? 73.195 -18.784 40.550 1.00 47.03 ? 36 VAL G CA 1 +ATOM 11697 C C . VAL G 1 36 ? 71.843 -18.915 41.192 1.00 53.62 ? 36 VAL G C 1 +ATOM 11698 O O . VAL G 1 36 ? 71.705 -18.802 42.419 1.00 65.15 ? 36 VAL G O 1 +ATOM 11699 C CB . VAL G 1 36 ? 73.694 -20.203 40.304 1.00 48.69 ? 36 VAL G CB 1 +ATOM 11700 C CG1 . VAL G 1 36 ? 73.550 -21.081 41.545 1.00 37.37 ? 36 VAL G CG1 1 +ATOM 11701 C CG2 . VAL G 1 36 ? 72.930 -20.786 39.134 1.00 63.66 ? 36 VAL G CG2 1 +ATOM 11702 N N . SER G 1 37 ? 70.814 -18.984 40.357 1.00 54.32 ? 37 SER G N 1 +ATOM 11703 C CA . SER G 1 37 ? 69.434 -18.995 40.858 1.00 64.78 ? 37 SER G CA 1 +ATOM 11704 C C . SER G 1 37 ? 68.785 -20.244 40.342 1.00 60.41 ? 37 SER G C 1 +ATOM 11705 O O . SER G 1 37 ? 68.840 -20.494 39.146 1.00 63.17 ? 37 SER G O 1 +ATOM 11706 C CB . SER G 1 37 ? 68.642 -17.769 40.351 1.00 64.82 ? 37 SER G CB 1 +ATOM 11707 O OG . SER G 1 37 ? 68.983 -16.569 41.020 1.00 50.45 ? 37 SER G OG 1 +ATOM 11708 N N . VAL G 1 38 ? 68.127 -20.994 41.213 1.00 55.15 ? 38 VAL G N 1 +ATOM 11709 C CA . VAL G 1 38 ? 67.248 -22.041 40.738 1.00 64.70 ? 38 VAL G CA 1 +ATOM 11710 C C . VAL G 1 38 ? 65.836 -21.808 41.241 1.00 85.23 ? 38 VAL G C 1 +ATOM 11711 O O . VAL G 1 38 ? 65.605 -21.793 42.459 1.00 70.43 ? 38 VAL G O 1 +ATOM 11712 C CB . VAL G 1 38 ? 67.682 -23.418 41.223 1.00 66.38 ? 38 VAL G CB 1 +ATOM 11713 C CG1 . VAL G 1 38 ? 66.709 -24.460 40.723 1.00 89.60 ? 38 VAL G CG1 1 +ATOM 11714 C CG2 . VAL G 1 38 ? 69.075 -23.754 40.726 1.00 82.48 ? 38 VAL G CG2 1 +ATOM 11715 N N . TYR G 1 39 ? 64.893 -21.623 40.298 1.00 109.32 ? 39 TYR G N 1 +ATOM 11716 C CA . TYR G 1 39 ? 63.483 -21.340 40.617 1.00 101.83 ? 39 TYR G CA 1 +ATOM 11717 C C . TYR G 1 39 ? 62.687 -22.653 40.734 1.00 86.25 ? 39 TYR G C 1 +ATOM 11718 O O . TYR G 1 39 ? 62.080 -22.932 41.772 1.00 78.49 ? 39 TYR G O 1 +ATOM 11719 C CB . TYR G 1 39 ? 62.862 -20.384 39.566 1.00 103.22 ? 39 TYR G CB 1 +ATOM 11720 C CG . TYR G 1 39 ? 63.100 -18.881 39.837 1.00 113.09 ? 39 TYR G CG 1 +ATOM 11721 C CD1 . TYR G 1 39 ? 64.308 -18.290 39.553 1.00 86.40 ? 39 TYR G CD1 1 +ATOM 11722 C CD2 . TYR G 1 39 ? 62.103 -18.080 40.428 1.00 116.03 ? 39 TYR G CD2 1 +ATOM 11723 C CE1 . TYR G 1 39 ? 64.533 -16.963 39.879 1.00 82.91 ? 39 TYR G CE1 1 +ATOM 11724 C CE2 . TYR G 1 39 ? 62.325 -16.756 40.759 1.00 78.40 ? 39 TYR G CE2 1 +ATOM 11725 C CZ . TYR G 1 39 ? 63.542 -16.201 40.479 1.00 74.20 ? 39 TYR G CZ 1 +ATOM 11726 O OH . TYR G 1 39 ? 63.768 -14.876 40.775 1.00 71.14 ? 39 TYR G OH 1 +ATOM 11727 N N . ASN G 1 40 ? 62.772 -23.502 39.718 1.00 88.84 ? 40 ASN G N 1 +ATOM 11728 C CA . ASN G 1 40 ? 62.074 -24.788 39.760 1.00 98.38 ? 40 ASN G CA 1 +ATOM 11729 C C . ASN G 1 40 ? 62.497 -25.780 38.671 1.00 100.12 ? 40 ASN G C 1 +ATOM 11730 O O . ASN G 1 40 ? 62.604 -25.425 37.492 1.00 117.90 ? 40 ASN G O 1 +ATOM 11731 C CB . ASN G 1 40 ? 60.579 -24.538 39.626 1.00 108.80 ? 40 ASN G CB 1 +ATOM 11732 C CG . ASN G 1 40 ? 59.750 -25.713 40.083 1.00 128.53 ? 40 ASN G CG 1 +ATOM 11733 O OD1 . ASN G 1 40 ? 59.045 -26.333 39.289 1.00 147.00 ? 40 ASN G OD1 1 +ATOM 11734 N ND2 . ASN G 1 40 ? 59.851 -26.045 41.364 1.00 145.07 ? 40 ASN G ND2 1 +ATOM 11735 N N . ILE G 1 41 ? 62.723 -27.029 39.065 1.00 94.87 ? 41 ILE G N 1 +ATOM 11736 C CA . ILE G 1 41 ? 62.900 -28.123 38.106 1.00 111.38 ? 41 ILE G CA 1 +ATOM 11737 C C . ILE G 1 41 ? 61.765 -29.140 38.272 1.00 113.99 ? 41 ILE G C 1 +ATOM 11738 O O . ILE G 1 41 ? 61.632 -29.750 39.337 1.00 142.77 ? 41 ILE G O 1 +ATOM 11739 C CB . ILE G 1 41 ? 64.259 -28.836 38.291 1.00 106.27 ? 41 ILE G CB 1 +ATOM 11740 C CG1 . ILE G 1 41 ? 65.385 -28.048 37.619 1.00 113.07 ? 41 ILE G CG1 1 +ATOM 11741 C CG2 . ILE G 1 41 ? 64.231 -30.196 37.623 1.00 94.53 ? 41 ILE G CG2 1 +ATOM 11742 C CD1 . ILE G 1 41 ? 65.769 -26.757 38.301 1.00 117.33 ? 41 ILE G CD1 1 +ATOM 11743 N N . GLN G 1 42 ? 60.943 -29.309 37.236 1.00 106.21 ? 42 GLN G N 1 +ATOM 11744 C CA . GLN G 1 42 ? 59.674 -30.051 37.372 1.00 115.84 ? 42 GLN G CA 1 +ATOM 11745 C C . GLN G 1 42 ? 59.834 -31.528 37.090 1.00 115.56 ? 42 GLN G C 1 +ATOM 11746 O O . GLN G 1 42 ? 60.749 -31.938 36.379 1.00 114.68 ? 42 GLN G O 1 +ATOM 11747 C CB . GLN G 1 42 ? 58.595 -29.506 36.433 1.00 108.19 ? 42 GLN G CB 1 +ATOM 11748 C CG . GLN G 1 42 ? 58.154 -28.097 36.748 1.00 107.60 ? 42 GLN G CG 1 +ATOM 11749 C CD . GLN G 1 42 ? 58.436 -27.144 35.596 1.00 121.21 ? 42 GLN G CD 1 +ATOM 11750 O OE1 . GLN G 1 42 ? 57.615 -26.990 34.688 1.00 144.07 ? 42 GLN G OE1 1 +ATOM 11751 N NE2 . GLN G 1 42 ? 59.610 -26.509 35.614 1.00 126.89 ? 42 GLN G NE2 1 +ATOM 11752 N N . ASP G 1 43 ? 58.907 -32.315 37.635 1.00 110.93 ? 43 ASP G N 1 +ATOM 11753 C CA . ASP G 1 43 ? 58.761 -33.725 37.291 1.00 111.93 ? 43 ASP G CA 1 +ATOM 11754 C C . ASP G 1 43 ? 57.987 -33.863 35.982 1.00 88.95 ? 43 ASP G C 1 +ATOM 11755 O O . ASP G 1 43 ? 56.880 -34.398 35.971 1.00 64.42 ? 43 ASP G O 1 +ATOM 11756 C CB . ASP G 1 43 ? 58.025 -34.476 38.411 1.00 120.25 ? 43 ASP G CB 1 +ATOM 11757 C CG . ASP G 1 43 ? 58.043 -36.001 38.220 1.00 145.55 ? 43 ASP G CG 1 +ATOM 11758 O OD1 . ASP G 1 43 ? 59.134 -36.559 37.980 1.00 132.72 ? 43 ASP G OD1 1 +ATOM 11759 O OD2 . ASP G 1 43 ? 56.973 -36.654 38.317 1.00 144.43 ? 43 ASP G OD2 1 +ATOM 11760 N N . GLU G 1 44 ? 58.588 -33.395 34.885 1.00 91.33 ? 44 GLU G N 1 +ATOM 11761 C CA . GLU G 1 44 ? 57.944 -33.407 33.570 1.00 97.15 ? 44 GLU G CA 1 +ATOM 11762 C C . GLU G 1 44 ? 57.809 -34.842 33.012 1.00 92.98 ? 44 GLU G C 1 +ATOM 11763 O O . GLU G 1 44 ? 57.481 -35.030 31.826 1.00 90.64 ? 44 GLU G O 1 +ATOM 11764 C CB . GLU G 1 44 ? 58.707 -32.495 32.574 1.00 105.41 ? 44 GLU G CB 1 +ATOM 11765 C CG . GLU G 1 44 ? 58.290 -31.016 32.576 1.00 109.75 ? 44 GLU G CG 1 +ATOM 11766 C CD . GLU G 1 44 ? 59.085 -30.124 31.595 1.00 143.74 ? 44 GLU G CD 1 +ATOM 11767 O OE1 . GLU G 1 44 ? 59.336 -30.505 30.423 1.00 160.41 ? 44 GLU G OE1 1 +ATOM 11768 O OE2 . GLU G 1 44 ? 59.481 -29.002 31.988 1.00 170.16 ? 44 GLU G OE2 1 +ATOM 11769 N N . THR G 1 45 ? 57.990 -35.840 33.883 1.00 92.25 ? 45 THR G N 1 +ATOM 11770 C CA . THR G 1 45 ? 58.062 -37.247 33.468 1.00 118.83 ? 45 THR G CA 1 +ATOM 11771 C C . THR G 1 45 ? 56.710 -37.861 33.085 1.00 103.40 ? 45 THR G C 1 +ATOM 11772 O O . THR G 1 45 ? 56.616 -38.609 32.122 1.00 95.12 ? 45 THR G O 1 +ATOM 11773 C CB . THR G 1 45 ? 58.779 -38.131 34.516 1.00 126.93 ? 45 THR G CB 1 +ATOM 11774 O OG1 . THR G 1 45 ? 59.104 -39.395 33.944 1.00 180.27 ? 45 THR G OG1 1 +ATOM 11775 C CG2 . THR G 1 45 ? 57.922 -38.382 35.750 1.00 134.21 ? 45 THR G CG2 1 +ATOM 11776 N N . GLY G 1 46 ? 55.672 -37.569 33.850 1.00 102.66 ? 46 GLY G N 1 +ATOM 11777 C CA . GLY G 1 46 ? 54.305 -37.989 33.498 1.00 105.77 ? 46 GLY G CA 1 +ATOM 11778 C C . GLY G 1 46 ? 53.955 -39.377 34.017 1.00 95.24 ? 46 GLY G C 1 +ATOM 11779 O O . GLY G 1 46 ? 52.984 -40.031 33.597 1.00 133.30 ? 46 GLY G O 1 +ATOM 11780 N N . GLN G 1 47 ? 54.655 -39.801 35.034 1.00 83.76 ? 47 GLN G N 1 +ATOM 11781 C CA . GLN G 1 47 ? 54.601 -41.172 35.333 1.00 90.26 ? 47 GLN G CA 1 +ATOM 11782 C C . GLN G 1 47 ? 54.353 -41.442 36.804 1.00 107.14 ? 47 GLN G C 1 +ATOM 11783 O O . GLN G 1 47 ? 54.894 -40.741 37.703 1.00 132.87 ? 47 GLN G O 1 +ATOM 11784 C CB . GLN G 1 47 ? 55.882 -41.767 34.861 1.00 104.99 ? 47 GLN G CB 1 +ATOM 11785 C CG . GLN G 1 47 ? 56.013 -41.777 33.346 1.00 96.03 ? 47 GLN G CG 1 +ATOM 11786 C CD . GLN G 1 47 ? 54.822 -42.369 32.649 1.00 111.04 ? 47 GLN G CD 1 +ATOM 11787 O OE1 . GLN G 1 47 ? 54.574 -43.564 32.729 1.00 140.36 ? 47 GLN G OE1 1 +ATOM 11788 N NE2 . GLN G 1 47 ? 54.050 -41.537 31.995 1.00 163.70 ? 47 GLN G NE2 1 +ATOM 11789 N N . PHE G 1 48 ? 53.518 -42.455 37.039 1.00 68.63 ? 48 PHE G N 1 +ATOM 11790 C CA . PHE G 1 48 ? 53.201 -42.885 38.393 1.00 86.32 ? 48 PHE G CA 1 +ATOM 11791 C C . PHE G 1 48 ? 53.531 -44.352 38.590 1.00 88.79 ? 48 PHE G C 1 +ATOM 11792 O O . PHE G 1 48 ? 53.692 -45.101 37.620 1.00 85.59 ? 48 PHE G O 1 +ATOM 11793 C CB . PHE G 1 48 ? 51.713 -42.629 38.689 1.00 107.44 ? 48 PHE G CB 1 +ATOM 11794 C CG . PHE G 1 48 ? 51.362 -41.190 38.738 1.00 89.39 ? 48 PHE G CG 1 +ATOM 11795 C CD1 . PHE G 1 48 ? 51.263 -40.475 37.559 1.00 70.41 ? 48 PHE G CD1 1 +ATOM 11796 C CD2 . PHE G 1 48 ? 51.232 -40.539 39.958 1.00 73.38 ? 48 PHE G CD2 1 +ATOM 11797 C CE1 . PHE G 1 48 ? 51.074 -39.125 37.584 1.00 75.01 ? 48 PHE G CE1 1 +ATOM 11798 C CE2 . PHE G 1 48 ? 51.026 -39.192 39.991 1.00 84.34 ? 48 PHE G CE2 1 +ATOM 11799 C CZ . PHE G 1 48 ? 50.921 -38.485 38.798 1.00 97.01 ? 48 PHE G CZ 1 +ATOM 11800 N N . LYS G 1 49 ? 53.496 -44.776 39.855 1.00 107.23 ? 49 LYS G N 1 +ATOM 11801 C CA . LYS G 1 49 ? 53.764 -46.159 40.210 1.00 111.98 ? 49 LYS G CA 1 +ATOM 11802 C C . LYS G 1 49 ? 52.571 -47.048 39.896 1.00 119.65 ? 49 LYS G C 1 +ATOM 11803 O O . LYS G 1 49 ? 51.411 -46.615 40.003 1.00 121.61 ? 49 LYS G O 1 +ATOM 11804 C CB . LYS G 1 49 ? 54.154 -46.276 41.688 1.00 99.20 ? 49 LYS G CB 1 +ATOM 11805 C CG . LYS G 1 49 ? 55.456 -45.548 41.966 1.00 115.11 ? 49 LYS G CG 1 +ATOM 11806 C CD . LYS G 1 49 ? 56.068 -45.770 43.334 1.00 140.89 ? 49 LYS G CD 1 +ATOM 11807 C CE . LYS G 1 49 ? 57.451 -45.096 43.316 1.00 177.55 ? 49 LYS G CE 1 +ATOM 11808 N NZ . LYS G 1 49 ? 58.249 -45.231 44.565 1.00 214.62 ? 49 LYS G NZ 1 +ATOM 11809 N N . PRO G 1 50 ? 52.857 -48.283 39.458 1.00 118.56 ? 50 PRO G N 1 +ATOM 11810 C CA . PRO G 1 50 ? 51.825 -49.267 39.161 1.00 123.79 ? 50 PRO G CA 1 +ATOM 11811 C C . PRO G 1 50 ? 51.259 -49.956 40.412 1.00 106.40 ? 50 PRO G C 1 +ATOM 11812 O O . PRO G 1 50 ? 51.782 -49.798 41.526 1.00 61.13 ? 50 PRO G O 1 +ATOM 11813 C CB . PRO G 1 50 ? 52.556 -50.292 38.295 1.00 130.10 ? 50 PRO G CB 1 +ATOM 11814 C CG . PRO G 1 50 ? 53.967 -50.218 38.766 1.00 144.61 ? 50 PRO G CG 1 +ATOM 11815 C CD . PRO G 1 50 ? 54.206 -48.793 39.165 1.00 120.63 ? 50 PRO G CD 1 +ATOM 11816 N N . TYR G 1 51 ? 50.162 -50.685 40.212 1.00 87.70 ? 51 TYR G N 1 +ATOM 11817 C CA . TYR G 1 51 ? 49.588 -51.472 41.278 1.00 74.37 ? 51 TYR G CA 1 +ATOM 11818 C C . TYR G 1 51 ? 50.683 -52.306 41.881 1.00 61.47 ? 51 TYR G C 1 +ATOM 11819 O O . TYR G 1 51 ? 51.484 -52.897 41.140 1.00 74.40 ? 51 TYR G O 1 +ATOM 11820 C CB . TYR G 1 51 ? 48.464 -52.373 40.738 1.00 78.40 ? 51 TYR G CB 1 +ATOM 11821 C CG . TYR G 1 51 ? 47.641 -52.970 41.854 1.00 76.22 ? 51 TYR G CG 1 +ATOM 11822 C CD1 . TYR G 1 51 ? 46.572 -52.262 42.386 1.00 97.15 ? 51 TYR G CD1 1 +ATOM 11823 C CD2 . TYR G 1 51 ? 47.935 -54.208 42.395 1.00 75.78 ? 51 TYR G CD2 1 +ATOM 11824 C CE1 . TYR G 1 51 ? 45.816 -52.758 43.431 1.00 98.25 ? 51 TYR G CE1 1 +ATOM 11825 C CE2 . TYR G 1 51 ? 47.163 -54.736 43.435 1.00 92.76 ? 51 TYR G CE2 1 +ATOM 11826 C CZ . TYR G 1 51 ? 46.128 -53.975 43.972 1.00 104.60 ? 51 TYR G CZ 1 +ATOM 11827 O OH . TYR G 1 51 ? 45.334 -54.424 45.006 1.00 109.78 ? 51 TYR G OH 1 +ATOM 11828 N N . PRO G 1 52 ? 50.713 -52.409 43.212 1.00 61.75 ? 52 PRO G N 1 +ATOM 11829 C CA . PRO G 1 52 ? 49.740 -51.951 44.211 1.00 70.29 ? 52 PRO G CA 1 +ATOM 11830 C C . PRO G 1 52 ? 49.975 -50.580 44.798 1.00 89.83 ? 52 PRO G C 1 +ATOM 11831 O O . PRO G 1 52 ? 49.447 -50.292 45.889 1.00 74.91 ? 52 PRO G O 1 +ATOM 11832 C CB . PRO G 1 52 ? 49.866 -53.000 45.323 1.00 70.95 ? 52 PRO G CB 1 +ATOM 11833 C CG . PRO G 1 52 ? 51.310 -53.386 45.274 1.00 89.74 ? 52 PRO G CG 1 +ATOM 11834 C CD . PRO G 1 52 ? 51.729 -53.294 43.816 1.00 76.25 ? 52 PRO G CD 1 +ATOM 11835 N N . ALA G 1 53 ? 50.795 -49.746 44.149 1.00 102.75 ? 53 ALA G N 1 +ATOM 11836 C CA . ALA G 1 53 ? 51.057 -48.406 44.696 1.00 115.32 ? 53 ALA G CA 1 +ATOM 11837 C C . ALA G 1 53 ? 49.745 -47.627 44.721 1.00 91.16 ? 53 ALA G C 1 +ATOM 11838 O O . ALA G 1 53 ? 48.823 -47.935 43.952 1.00 88.57 ? 53 ALA G O 1 +ATOM 11839 C CB . ALA G 1 53 ? 52.142 -47.663 43.894 1.00 113.80 ? 53 ALA G CB 1 +ATOM 11840 N N . SER G 1 54 ? 49.675 -46.598 45.561 1.00 65.91 ? 54 SER G N 1 +ATOM 11841 C CA . SER G 1 54 ? 48.610 -45.633 45.392 1.00 49.57 ? 54 SER G CA 1 +ATOM 11842 C C . SER G 1 54 ? 48.646 -45.040 43.992 1.00 56.11 ? 54 SER G C 1 +ATOM 11843 O O . SER G 1 54 ? 49.717 -44.827 43.343 1.00 75.42 ? 54 SER G O 1 +ATOM 11844 C CB . SER G 1 54 ? 48.720 -44.500 46.369 1.00 58.25 ? 54 SER G CB 1 +ATOM 11845 O OG . SER G 1 54 ? 48.006 -43.333 45.932 1.00 41.23 ? 54 SER G OG 1 +ATOM 11846 N N . ASN G 1 55 ? 47.451 -44.812 43.477 1.00 57.94 ? 55 ASN G N 1 +ATOM 11847 C CA . ASN G 1 55 ? 47.291 -44.226 42.161 1.00 54.58 ? 55 ASN G CA 1 +ATOM 11848 C C . ASN G 1 55 ? 48.185 -42.988 42.006 1.00 52.15 ? 55 ASN G C 1 +ATOM 11849 O O . ASN G 1 55 ? 48.590 -42.602 40.895 1.00 32.48 ? 55 ASN G O 1 +ATOM 11850 C CB . ASN G 1 55 ? 45.814 -43.875 41.979 1.00 45.38 ? 55 ASN G CB 1 +ATOM 11851 C CG . ASN G 1 55 ? 45.500 -43.531 40.560 1.00 76.14 ? 55 ASN G CG 1 +ATOM 11852 O OD1 . ASN G 1 55 ? 46.184 -43.948 39.606 1.00 116.54 ? 55 ASN G OD1 1 +ATOM 11853 N ND2 . ASN G 1 55 ? 44.428 -42.826 40.389 1.00 100.63 ? 55 ASN G ND2 1 +ATOM 11854 N N . PHE G 1 56 ? 48.391 -42.316 43.148 1.00 59.78 ? 56 PHE G N 1 +ATOM 11855 C CA . PHE G 1 56 ? 48.940 -40.957 43.197 1.00 66.47 ? 56 PHE G CA 1 +ATOM 11856 C C . PHE G 1 56 ? 50.413 -40.930 43.508 1.00 65.53 ? 56 PHE G C 1 +ATOM 11857 O O . PHE G 1 56 ? 51.013 -39.867 43.578 1.00 71.50 ? 56 PHE G O 1 +ATOM 11858 C CB . PHE G 1 56 ? 48.261 -40.123 44.285 1.00 59.61 ? 56 PHE G CB 1 +ATOM 11859 C CG . PHE G 1 56 ? 46.786 -39.966 44.099 1.00 51.70 ? 56 PHE G CG 1 +ATOM 11860 C CD1 . PHE G 1 56 ? 46.249 -39.363 42.964 1.00 43.84 ? 56 PHE G CD1 1 +ATOM 11861 C CD2 . PHE G 1 56 ? 45.949 -40.428 45.046 1.00 62.51 ? 56 PHE G CD2 1 +ATOM 11862 C CE1 . PHE G 1 56 ? 44.898 -39.265 42.789 1.00 47.34 ? 56 PHE G CE1 1 +ATOM 11863 C CE2 . PHE G 1 56 ? 44.577 -40.277 44.905 1.00 74.34 ? 56 PHE G CE2 1 +ATOM 11864 C CZ . PHE G 1 56 ? 44.051 -39.719 43.764 1.00 56.30 ? 56 PHE G CZ 1 +ATOM 11865 N N . SER G 1 57 ? 50.988 -42.087 43.749 1.00 60.16 ? 57 SER G N 1 +ATOM 11866 C CA . SER G 1 57 ? 52.422 -42.140 43.967 1.00 56.23 ? 57 SER G CA 1 +ATOM 11867 C C . SER G 1 57 ? 53.202 -41.906 42.635 1.00 59.97 ? 57 SER G C 1 +ATOM 11868 O O . SER G 1 57 ? 53.129 -42.675 41.674 1.00 52.44 ? 57 SER G O 1 +ATOM 11869 C CB . SER G 1 57 ? 52.787 -43.476 44.600 1.00 63.09 ? 57 SER G CB 1 +ATOM 11870 O OG . SER G 1 57 ? 52.312 -43.516 45.942 1.00 49.96 ? 57 SER G OG 1 +ATOM 11871 N N . THR G 1 58 ? 53.932 -40.817 42.581 1.00 71.66 ? 58 THR G N 1 +ATOM 11872 C CA . THR G 1 58 ? 54.702 -40.495 41.398 1.00 90.46 ? 58 THR G CA 1 +ATOM 11873 C C . THR G 1 58 ? 55.859 -41.430 41.240 1.00 89.25 ? 58 THR G C 1 +ATOM 11874 O O . THR G 1 58 ? 56.432 -41.904 42.218 1.00 92.20 ? 58 THR G O 1 +ATOM 11875 C CB . THR G 1 58 ? 55.272 -39.076 41.504 1.00 119.44 ? 58 THR G CB 1 +ATOM 11876 O OG1 . THR G 1 58 ? 56.125 -38.965 42.654 1.00 79.74 ? 58 THR G OG1 1 +ATOM 11877 C CG2 . THR G 1 58 ? 54.147 -38.099 41.673 1.00 155.38 ? 58 THR G CG2 1 +ATOM 11878 N N . ALA G 1 59 ? 56.324 -41.580 40.023 1.00 88.10 ? 59 ALA G N 1 +ATOM 11879 C CA . ALA G 1 59 ? 57.409 -42.506 39.839 1.00 110.55 ? 59 ALA G CA 1 +ATOM 11880 C C . ALA G 1 59 ? 58.735 -41.887 40.232 1.00 113.07 ? 59 ALA G C 1 +ATOM 11881 O O . ALA G 1 59 ? 59.699 -42.605 40.528 1.00 152.82 ? 59 ALA G O 1 +ATOM 11882 C CB . ALA G 1 59 ? 57.464 -42.966 38.413 1.00 115.71 ? 59 ALA G CB 1 +ATOM 11883 N N . VAL G 1 60 ? 58.771 -40.558 40.287 1.00 103.43 ? 60 VAL G N 1 +ATOM 11884 C CA . VAL G 1 60 ? 60.011 -39.811 40.537 1.00 95.72 ? 60 VAL G CA 1 +ATOM 11885 C C . VAL G 1 60 ? 59.772 -38.765 41.611 1.00 100.48 ? 60 VAL G C 1 +ATOM 11886 O O . VAL G 1 60 ? 58.701 -38.160 41.657 1.00 169.88 ? 60 VAL G O 1 +ATOM 11887 C CB . VAL G 1 60 ? 60.444 -39.096 39.254 1.00 80.18 ? 60 VAL G CB 1 +ATOM 11888 C CG1 . VAL G 1 60 ? 61.702 -38.302 39.464 1.00 65.28 ? 60 VAL G CG1 1 +ATOM 11889 C CG2 . VAL G 1 60 ? 60.624 -40.128 38.143 1.00 124.33 ? 60 VAL G CG2 1 +ATOM 11890 N N . PRO G 1 61 ? 60.726 -38.606 42.537 1.00 105.12 ? 61 PRO G N 1 +ATOM 11891 C CA . PRO G 1 61 ? 60.501 -37.625 43.583 1.00 127.61 ? 61 PRO G CA 1 +ATOM 11892 C C . PRO G 1 61 ? 60.393 -36.207 43.009 1.00 144.14 ? 61 PRO G C 1 +ATOM 11893 O O . PRO G 1 61 ? 61.117 -35.861 42.061 1.00 157.41 ? 61 PRO G O 1 +ATOM 11894 C CB . PRO G 1 61 ? 61.735 -37.782 44.485 1.00 116.80 ? 61 PRO G CB 1 +ATOM 11895 C CG . PRO G 1 61 ? 62.759 -38.436 43.624 1.00 92.36 ? 61 PRO G CG 1 +ATOM 11896 C CD . PRO G 1 61 ? 61.985 -39.335 42.731 1.00 92.90 ? 61 PRO G CD 1 +ATOM 11897 N N . GLN G 1 62 ? 59.560 -35.383 43.644 1.00 125.18 ? 62 GLN G N 1 +ATOM 11898 C CA . GLN G 1 62 ? 59.309 -34.025 43.176 1.00 114.63 ? 62 GLN G CA 1 +ATOM 11899 C C . GLN G 1 62 ? 60.328 -33.018 43.690 1.00 110.32 ? 62 GLN G C 1 +ATOM 11900 O O . GLN G 1 62 ? 59.980 -31.906 44.032 1.00 90.83 ? 62 GLN G O 1 +ATOM 11901 C CB . GLN G 1 62 ? 57.902 -33.597 43.617 1.00 132.36 ? 62 GLN G CB 1 +ATOM 11902 C CG . GLN G 1 62 ? 56.807 -34.593 43.284 1.00 122.34 ? 62 GLN G CG 1 +ATOM 11903 C CD . GLN G 1 62 ? 56.753 -34.876 41.798 1.00 127.72 ? 62 GLN G CD 1 +ATOM 11904 O OE1 . GLN G 1 62 ? 56.226 -34.085 41.021 1.00 160.10 ? 62 GLN G OE1 1 +ATOM 11905 N NE2 . GLN G 1 62 ? 57.335 -35.979 41.389 1.00 149.40 ? 62 GLN G NE2 1 +ATOM 11906 N N . SER G 1 63 ? 61.568 -33.452 43.850 1.00 130.71 ? 63 SER G N 1 +ATOM 11907 C CA . SER G 1 63 ? 62.509 -32.781 44.749 1.00 128.01 ? 63 SER G CA 1 +ATOM 11908 C C . SER G 1 63 ? 63.749 -32.323 43.995 1.00 103.98 ? 63 SER G C 1 +ATOM 11909 O O . SER G 1 63 ? 64.738 -31.915 44.597 1.00 115.64 ? 63 SER G O 1 +ATOM 11910 C CB . SER G 1 63 ? 62.881 -33.710 45.940 1.00 138.89 ? 63 SER G CB 1 +ATOM 11911 O OG . SER G 1 63 ? 63.526 -34.922 45.549 1.00 120.20 ? 63 SER G OG 1 +ATOM 11912 N N . ALA G 1 64 ? 63.699 -32.462 42.678 1.00 87.46 ? 64 ALA G N 1 +ATOM 11913 C CA . ALA G 1 64 ? 64.854 -32.236 41.816 1.00 76.77 ? 64 ALA G CA 1 +ATOM 11914 C C . ALA G 1 64 ? 65.472 -30.847 41.986 1.00 76.79 ? 64 ALA G C 1 +ATOM 11915 O O . ALA G 1 64 ? 66.700 -30.701 42.016 1.00 103.72 ? 64 ALA G O 1 +ATOM 11916 C CB . ALA G 1 64 ? 64.440 -32.428 40.382 1.00 79.04 ? 64 ALA G CB 1 +ATOM 11917 N N . THR G 1 65 ? 64.618 -29.863 42.225 1.00 89.49 ? 65 THR G N 1 +ATOM 11918 C CA . THR G 1 65 ? 65.035 -28.492 42.442 1.00 100.56 ? 65 THR G CA 1 +ATOM 11919 C C . THR G 1 65 ? 66.054 -28.355 43.559 1.00 102.11 ? 65 THR G C 1 +ATOM 11920 O O . THR G 1 65 ? 67.126 -27.752 43.372 1.00 125.23 ? 65 THR G O 1 +ATOM 11921 C CB . THR G 1 65 ? 63.836 -27.640 42.854 1.00 116.60 ? 65 THR G CB 1 +ATOM 11922 O OG1 . THR G 1 65 ? 62.701 -28.060 42.094 1.00 163.64 ? 65 THR G OG1 1 +ATOM 11923 C CG2 . THR G 1 65 ? 64.117 -26.154 42.620 1.00 120.92 ? 65 THR G CG2 1 +ATOM 11924 N N . ALA G 1 66 ? 65.738 -28.935 44.709 1.00 80.55 ? 66 ALA G N 1 +ATOM 11925 C CA . ALA G 1 66 ? 66.626 -28.838 45.846 1.00 90.98 ? 66 ALA G CA 1 +ATOM 11926 C C . ALA G 1 66 ? 67.938 -29.623 45.642 1.00 91.90 ? 66 ALA G C 1 +ATOM 11927 O O . ALA G 1 66 ? 69.022 -29.203 46.085 1.00 82.18 ? 66 ALA G O 1 +ATOM 11928 C CB . ALA G 1 66 ? 65.903 -29.313 47.090 1.00 108.14 ? 66 ALA G CB 1 +ATOM 11929 N N . MET G 1 67 ? 67.838 -30.756 44.948 1.00 96.45 ? 67 MET G N 1 +ATOM 11930 C CA . MET G 1 67 ? 69.024 -31.552 44.593 1.00 109.52 ? 67 MET G CA 1 +ATOM 11931 C C . MET G 1 67 ? 69.991 -30.756 43.695 1.00 97.71 ? 67 MET G C 1 +ATOM 11932 O O . MET G 1 67 ? 71.206 -30.795 43.890 1.00 70.06 ? 67 MET G O 1 +ATOM 11933 C CB . MET G 1 67 ? 68.622 -32.856 43.875 1.00 113.32 ? 67 MET G CB 1 +ATOM 11934 C CG . MET G 1 67 ? 67.915 -33.888 44.746 1.00 131.36 ? 67 MET G CG 1 +ATOM 11935 S SD . MET G 1 67 ? 67.190 -35.208 43.741 1.00 136.93 ? 67 MET G SD 1 +ATOM 11936 C CE . MET G 1 67 ? 66.604 -36.332 45.016 1.00 130.14 ? 67 MET G CE 1 +ATOM 11937 N N . LEU G 1 68 ? 69.434 -30.060 42.708 1.00 101.29 ? 68 LEU G N 1 +ATOM 11938 C CA . LEU G 1 68 ? 70.240 -29.262 41.811 1.00 87.98 ? 68 LEU G CA 1 +ATOM 11939 C C . LEU G 1 68 ? 70.922 -28.148 42.565 1.00 106.20 ? 68 LEU G C 1 +ATOM 11940 O O . LEU G 1 68 ? 72.098 -27.905 42.360 1.00 93.21 ? 68 LEU G O 1 +ATOM 11941 C CB . LEU G 1 68 ? 69.394 -28.654 40.705 1.00 112.63 ? 68 LEU G CB 1 +ATOM 11942 C CG . LEU G 1 68 ? 70.166 -27.613 39.869 1.00 139.72 ? 68 LEU G CG 1 +ATOM 11943 C CD1 . LEU G 1 68 ? 71.292 -28.281 39.098 1.00 148.53 ? 68 LEU G CD1 1 +ATOM 11944 C CD2 . LEU G 1 68 ? 69.257 -26.845 38.915 1.00 136.40 ? 68 LEU G CD2 1 +ATOM 11945 N N . VAL G 1 69 ? 70.181 -27.448 43.432 1.00 150.68 ? 69 VAL G N 1 +ATOM 11946 C CA . VAL G 1 69 ? 70.770 -26.356 44.225 1.00 141.37 ? 69 VAL G CA 1 +ATOM 11947 C C . VAL G 1 69 ? 71.923 -26.899 45.071 1.00 140.03 ? 69 VAL G C 1 +ATOM 11948 O O . VAL G 1 69 ? 72.999 -26.300 45.153 1.00 125.30 ? 69 VAL G O 1 +ATOM 11949 C CB . VAL G 1 69 ? 69.748 -25.668 45.156 1.00 121.78 ? 69 VAL G CB 1 +ATOM 11950 C CG1 . VAL G 1 69 ? 70.467 -24.676 46.060 1.00 101.40 ? 69 VAL G CG1 1 +ATOM 11951 C CG2 . VAL G 1 69 ? 68.654 -24.954 44.362 1.00 102.71 ? 69 VAL G CG2 1 +ATOM 11952 N N . THR G 1 70 ? 71.693 -28.057 45.683 1.00 133.36 ? 70 THR G N 1 +ATOM 11953 C CA . THR G 1 70 ? 72.704 -28.694 46.516 1.00 125.90 ? 70 THR G CA 1 +ATOM 11954 C C . THR G 1 70 ? 73.934 -29.082 45.700 1.00 102.90 ? 70 THR G C 1 +ATOM 11955 O O . THR G 1 70 ? 75.081 -28.831 46.114 1.00 104.79 ? 70 THR G O 1 +ATOM 11956 C CB . THR G 1 70 ? 72.123 -29.929 47.224 1.00 112.56 ? 70 THR G CB 1 +ATOM 11957 O OG1 . THR G 1 70 ? 70.966 -29.524 47.970 1.00 80.68 ? 70 THR G OG1 1 +ATOM 11958 C CG2 . THR G 1 70 ? 73.170 -30.554 48.174 1.00 127.67 ? 70 THR G CG2 1 +ATOM 11959 N N . ALA G 1 71 ? 73.698 -29.670 44.536 1.00 86.77 ? 71 ALA G N 1 +ATOM 11960 C CA . ALA G 1 71 ? 74.807 -30.027 43.653 1.00 107.61 ? 71 ALA G CA 1 +ATOM 11961 C C . ALA G 1 71 ? 75.601 -28.789 43.219 1.00 93.81 ? 71 ALA G C 1 +ATOM 11962 O O . ALA G 1 71 ? 76.839 -28.804 43.165 1.00 76.85 ? 71 ALA G O 1 +ATOM 11963 C CB . ALA G 1 71 ? 74.293 -30.791 42.436 1.00 104.97 ? 71 ALA G CB 1 +ATOM 11964 N N . LEU G 1 72 ? 74.878 -27.725 42.902 1.00 103.05 ? 72 LEU G N 1 +ATOM 11965 C CA . LEU G 1 72 ? 75.512 -26.468 42.496 1.00 116.50 ? 72 LEU G CA 1 +ATOM 11966 C C . LEU G 1 72 ? 76.382 -25.921 43.610 1.00 114.21 ? 72 LEU G C 1 +ATOM 11967 O O . LEU G 1 72 ? 77.329 -25.185 43.354 1.00 118.68 ? 72 LEU G O 1 +ATOM 11968 C CB . LEU G 1 72 ? 74.459 -25.414 42.095 1.00 104.77 ? 72 LEU G CB 1 +ATOM 11969 C CG . LEU G 1 72 ? 73.698 -25.717 40.811 1.00 81.86 ? 72 LEU G CG 1 +ATOM 11970 C CD1 . LEU G 1 72 ? 72.468 -24.883 40.767 1.00 70.62 ? 72 LEU G CD1 1 +ATOM 11971 C CD2 . LEU G 1 72 ? 74.545 -25.472 39.581 1.00 101.08 ? 72 LEU G CD2 1 +ATOM 11972 N N . LYS G 1 73 ? 76.038 -26.252 44.852 1.00 93.76 ? 73 LYS G N 1 +ATOM 11973 C CA . LYS G 1 73 ? 76.817 -25.761 45.977 1.00 104.68 ? 73 LYS G CA 1 +ATOM 11974 C C . LYS G 1 73 ? 78.038 -26.643 46.186 1.00 103.94 ? 73 LYS G C 1 +ATOM 11975 O O . LYS G 1 73 ? 79.117 -26.141 46.452 1.00 105.45 ? 73 LYS G O 1 +ATOM 11976 C CB . LYS G 1 73 ? 75.979 -25.676 47.271 1.00 121.18 ? 73 LYS G CB 1 +ATOM 11977 C CG . LYS G 1 73 ? 76.675 -24.887 48.396 1.00 113.99 ? 73 LYS G CG 1 +ATOM 11978 C CD . LYS G 1 73 ? 75.841 -24.805 49.680 1.00 104.04 ? 73 LYS G CD 1 +ATOM 11979 C CE . LYS G 1 73 ? 76.724 -24.642 50.915 1.00 82.27 ? 73 LYS G CE 1 +ATOM 11980 N NZ . LYS G 1 73 ? 76.590 -23.319 51.582 1.00 56.87 ? 73 LYS G NZ 1 +ATOM 11981 N N . ASP G 1 74 ? 77.832 -27.958 46.180 1.00 104.49 ? 74 ASP G N 1 +ATOM 11982 C CA . ASP G 1 74 ? 78.892 -28.905 46.532 1.00 96.48 ? 74 ASP G CA 1 +ATOM 11983 C C . ASP G 1 74 ? 80.047 -28.761 45.564 1.00 91.78 ? 74 ASP G C 1 +ATOM 11984 O O . ASP G 1 74 ? 81.193 -29.059 45.919 1.00 135.75 ? 74 ASP G O 1 +ATOM 11985 C CB . ASP G 1 74 ? 78.362 -30.347 46.526 1.00 100.34 ? 74 ASP G CB 1 +ATOM 11986 C CG . ASP G 1 74 ? 77.396 -30.647 47.686 1.00 85.44 ? 74 ASP G CG 1 +ATOM 11987 O OD1 . ASP G 1 74 ? 77.498 -30.020 48.775 1.00 52.46 ? 74 ASP G OD1 1 +ATOM 11988 O OD2 . ASP G 1 74 ? 76.522 -31.528 47.482 1.00 68.76 ? 74 ASP G OD2 1 +ATOM 11989 N N . SER G 1 75 ? 79.744 -28.318 44.345 1.00 79.46 ? 75 SER G N 1 +ATOM 11990 C CA . SER G 1 75 ? 80.762 -28.204 43.293 1.00 122.13 ? 75 SER G CA 1 +ATOM 11991 C C . SER G 1 75 ? 81.844 -27.180 43.626 1.00 116.26 ? 75 SER G C 1 +ATOM 11992 O O . SER G 1 75 ? 82.957 -27.235 43.093 1.00 90.59 ? 75 SER G O 1 +ATOM 11993 C CB . SER G 1 75 ? 80.114 -27.837 41.957 1.00 144.18 ? 75 SER G CB 1 +ATOM 11994 O OG . SER G 1 75 ? 79.938 -26.434 41.836 1.00 171.99 ? 75 SER G OG 1 +ATOM 11995 N N . ARG G 1 76 ? 81.485 -26.236 44.486 1.00 112.08 ? 76 ARG G N 1 +ATOM 11996 C CA . ARG G 1 76 ? 82.353 -25.124 44.840 1.00 133.89 ? 76 ARG G CA 1 +ATOM 11997 C C . ARG G 1 76 ? 82.723 -24.313 43.611 1.00 121.51 ? 76 ARG G C 1 +ATOM 11998 O O . ARG G 1 76 ? 83.795 -23.724 43.543 1.00 110.13 ? 76 ARG G O 1 +ATOM 11999 C CB . ARG G 1 76 ? 83.610 -25.610 45.540 1.00 144.44 ? 76 ARG G CB 1 +ATOM 12000 C CG . ARG G 1 76 ? 83.357 -26.378 46.828 1.00 133.45 ? 76 ARG G CG 1 +ATOM 12001 C CD . ARG G 1 76 ? 84.678 -26.788 47.449 1.00 151.34 ? 76 ARG G CD 1 +ATOM 12002 N NE . ARG G 1 76 ? 85.342 -27.813 46.637 1.00 149.15 ? 76 ARG G NE 1 +ATOM 12003 C CZ . ARG G 1 76 ? 86.278 -27.576 45.717 1.00 165.61 ? 76 ARG G CZ 1 +ATOM 12004 N NH1 . ARG G 1 76 ? 86.688 -26.334 45.438 1.00 157.01 ? 76 ARG G NH1 1 +ATOM 12005 N NH2 . ARG G 1 76 ? 86.805 -28.598 45.061 1.00 166.35 ? 76 ARG G NH2 1 +ATOM 12006 N N . TRP G 1 77 ? 81.745 -24.160 42.728 1.00 139.09 ? 77 TRP G N 1 +ATOM 12007 C CA . TRP G 1 77 ? 81.791 -23.191 41.638 1.00 153.85 ? 77 TRP G CA 1 +ATOM 12008 C C . TRP G 1 77 ? 80.716 -22.072 41.775 1.00 161.43 ? 77 TRP G C 1 +ATOM 12009 O O . TRP G 1 77 ? 80.945 -20.922 41.379 1.00 90.93 ? 77 TRP G O 1 +ATOM 12010 C CB . TRP G 1 77 ? 81.582 -23.941 40.329 1.00 142.37 ? 77 TRP G CB 1 +ATOM 12011 C CG . TRP G 1 77 ? 82.819 -24.418 39.707 1.00 114.00 ? 77 TRP G CG 1 +ATOM 12012 C CD1 . TRP G 1 77 ? 83.569 -25.481 40.088 1.00 92.83 ? 77 TRP G CD1 1 +ATOM 12013 C CD2 . TRP G 1 77 ? 83.448 -23.861 38.546 1.00 96.17 ? 77 TRP G CD2 1 +ATOM 12014 N NE1 . TRP G 1 77 ? 84.638 -25.608 39.251 1.00 110.39 ? 77 TRP G NE1 1 +ATOM 12015 C CE2 . TRP G 1 77 ? 84.586 -24.618 38.299 1.00 91.87 ? 77 TRP G CE2 1 +ATOM 12016 C CE3 . TRP G 1 77 ? 83.161 -22.782 37.703 1.00 90.37 ? 77 TRP G CE3 1 +ATOM 12017 C CZ2 . TRP G 1 77 ? 85.446 -24.340 37.238 1.00 93.95 ? 77 TRP G CZ2 1 +ATOM 12018 C CZ3 . TRP G 1 77 ? 84.026 -22.499 36.667 1.00 89.03 ? 77 TRP G CZ3 1 +ATOM 12019 C CH2 . TRP G 1 77 ? 85.150 -23.277 36.440 1.00 87.02 ? 77 TRP G CH2 1 +ATOM 12020 N N . PHE G 1 78 ? 79.579 -22.417 42.382 1.00 178.03 ? 78 PHE G N 1 +ATOM 12021 C CA . PHE G 1 78 ? 78.405 -21.545 42.443 1.00 146.95 ? 78 PHE G CA 1 +ATOM 12022 C C . PHE G 1 78 ? 77.949 -21.275 43.874 1.00 132.13 ? 78 PHE G C 1 +ATOM 12023 O O . PHE G 1 78 ? 77.994 -22.171 44.713 1.00 98.31 ? 78 PHE G O 1 +ATOM 12024 C CB . PHE G 1 78 ? 77.240 -22.200 41.716 1.00 138.86 ? 78 PHE G CB 1 +ATOM 12025 C CG . PHE G 1 78 ? 77.541 -22.577 40.297 1.00 141.37 ? 78 PHE G CG 1 +ATOM 12026 C CD1 . PHE G 1 78 ? 77.638 -21.599 39.298 1.00 111.04 ? 78 PHE G CD1 1 +ATOM 12027 C CD2 . PHE G 1 78 ? 77.701 -23.916 39.954 1.00 114.13 ? 78 PHE G CD2 1 +ATOM 12028 C CE1 . PHE G 1 78 ? 77.847 -21.956 37.989 1.00 83.54 ? 78 PHE G CE1 1 +ATOM 12029 C CE2 . PHE G 1 78 ? 77.920 -24.280 38.645 1.00 94.74 ? 78 PHE G CE2 1 +ATOM 12030 C CZ . PHE G 1 78 ? 77.991 -23.296 37.662 1.00 94.60 ? 78 PHE G CZ 1 +ATOM 12031 N N . ILE G 1 79 ? 77.490 -20.044 44.113 1.00 132.27 ? 79 ILE G N 1 +ATOM 12032 C CA . ILE G 1 79 ? 76.699 -19.683 45.296 1.00 108.04 ? 79 ILE G CA 1 +ATOM 12033 C C . ILE G 1 79 ? 75.236 -19.654 44.901 1.00 112.07 ? 79 ILE G C 1 +ATOM 12034 O O . ILE G 1 79 ? 74.901 -19.035 43.884 1.00 107.36 ? 79 ILE G O 1 +ATOM 12035 C CB . ILE G 1 79 ? 77.030 -18.281 45.771 1.00 94.80 ? 79 ILE G CB 1 +ATOM 12036 C CG1 . ILE G 1 79 ? 78.541 -18.086 45.890 1.00 114.19 ? 79 ILE G CG1 1 +ATOM 12037 C CG2 . ILE G 1 79 ? 76.367 -18.015 47.112 1.00 110.35 ? 79 ILE G CG2 1 +ATOM 12038 C CD1 . ILE G 1 79 ? 78.988 -16.631 45.820 1.00 112.50 ? 79 ILE G CD1 1 +ATOM 12039 N N . PRO G 1 80 ? 74.413 -20.478 45.568 1.00 132.17 ? 80 PRO G N 1 +ATOM 12040 C CA . PRO G 1 80 ? 73.038 -20.491 45.117 1.00 131.30 ? 80 PRO G CA 1 +ATOM 12041 C C . PRO G 1 80 ? 72.266 -19.500 45.902 1.00 114.83 ? 80 PRO G C 1 +ATOM 12042 O O . PRO G 1 80 ? 72.458 -19.384 47.113 1.00 135.66 ? 80 PRO G O 1 +ATOM 12043 C CB . PRO G 1 80 ? 72.560 -21.910 45.435 1.00 116.60 ? 80 PRO G CB 1 +ATOM 12044 C CG . PRO G 1 80 ? 73.794 -22.723 45.441 1.00 162.06 ? 80 PRO G CG 1 +ATOM 12045 C CD . PRO G 1 80 ? 74.801 -21.800 46.093 1.00 163.15 ? 80 PRO G CD 1 +ATOM 12046 N N . LEU G 1 81 ? 71.472 -18.724 45.198 1.00 91.51 ? 81 LEU G N 1 +ATOM 12047 C CA . LEU G 1 81 ? 70.610 -17.786 45.828 1.00 104.09 ? 81 LEU G CA 1 +ATOM 12048 C C . LEU G 1 81 ? 69.263 -18.420 45.977 1.00 96.37 ? 81 LEU G C 1 +ATOM 12049 O O . LEU G 1 81 ? 68.808 -19.150 45.090 1.00 95.65 ? 81 LEU G O 1 +ATOM 12050 C CB . LEU G 1 81 ? 70.545 -16.499 45.015 1.00 130.15 ? 81 LEU G CB 1 +ATOM 12051 C CG . LEU G 1 81 ? 71.941 -15.898 44.784 1.00 145.97 ? 81 LEU G CG 1 +ATOM 12052 C CD1 . LEU G 1 81 ? 71.810 -14.704 43.868 1.00 103.02 ? 81 LEU G CD1 1 +ATOM 12053 C CD2 . LEU G 1 81 ? 72.579 -15.490 46.102 1.00 157.93 ? 81 LEU G CD2 1 +ATOM 12054 N N . GLU G 1 82 ? 68.660 -18.178 47.142 1.00 139.22 ? 82 GLU G N 1 +ATOM 12055 C CA . GLU G 1 82 ? 67.376 -18.778 47.497 1.00 174.86 ? 82 GLU G CA 1 +ATOM 12056 C C . GLU G 1 82 ? 66.195 -18.095 46.786 1.00 143.64 ? 82 GLU G C 1 +ATOM 12057 O O . GLU G 1 82 ? 65.803 -16.970 47.116 1.00 91.08 ? 82 GLU G O 1 +ATOM 12058 C CB . GLU G 1 82 ? 67.153 -18.789 49.023 1.00 188.75 ? 82 GLU G CB 1 +ATOM 12059 C CG . GLU G 1 82 ? 65.833 -19.427 49.481 1.00 189.51 ? 82 GLU G CG 1 +ATOM 12060 C CD . GLU G 1 82 ? 65.762 -20.957 49.304 1.00 150.25 ? 82 GLU G CD 1 +ATOM 12061 O OE1 . GLU G 1 82 ? 66.058 -21.501 48.210 1.00 113.10 ? 82 GLU G OE1 1 +ATOM 12062 O OE2 . GLU G 1 82 ? 65.311 -21.635 50.250 1.00 123.81 ? 82 GLU G OE2 1 +ATOM 12063 N N . ARG G 1 83 ? 65.612 -18.836 45.852 1.00 125.09 ? 83 ARG G N 1 +ATOM 12064 C CA . ARG G 1 83 ? 64.409 -18.430 45.172 1.00 109.43 ? 83 ARG G CA 1 +ATOM 12065 C C . ARG G 1 83 ? 63.267 -19.456 45.331 1.00 94.31 ? 83 ARG G C 1 +ATOM 12066 O O . ARG G 1 83 ? 62.114 -19.113 45.094 1.00 100.15 ? 83 ARG G O 1 +ATOM 12067 C CB . ARG G 1 83 ? 64.727 -18.162 43.691 1.00 116.09 ? 83 ARG G CB 1 +ATOM 12068 C CG . ARG G 1 83 ? 65.836 -17.150 43.465 1.00 97.85 ? 83 ARG G CG 1 +ATOM 12069 C CD . ARG G 1 83 ? 65.411 -15.757 43.857 1.00 102.17 ? 83 ARG G CD 1 +ATOM 12070 N NE . ARG G 1 83 ? 66.433 -14.829 43.397 1.00 120.29 ? 83 ARG G NE 1 +ATOM 12071 C CZ . ARG G 1 83 ? 67.371 -14.258 44.159 1.00 138.48 ? 83 ARG G CZ 1 +ATOM 12072 N NH1 . ARG G 1 83 ? 67.395 -14.420 45.482 1.00 90.10 ? 83 ARG G NH1 1 +ATOM 12073 N NH2 . ARG G 1 83 ? 68.274 -13.464 43.576 1.00 188.68 ? 83 ARG G NH2 1 +ATOM 12074 N N . GLN G 1 84 ? 63.564 -20.705 45.701 1.00 77.75 ? 84 GLN G N 1 +ATOM 12075 C CA . GLN G 1 84 ? 62.486 -21.702 45.818 1.00 84.94 ? 84 GLN G CA 1 +ATOM 12076 C C . GLN G 1 84 ? 61.507 -21.256 46.880 1.00 86.74 ? 84 GLN G C 1 +ATOM 12077 O O . GLN G 1 84 ? 60.310 -21.308 46.685 1.00 129.90 ? 84 GLN G O 1 +ATOM 12078 C CB . GLN G 1 84 ? 62.990 -23.125 46.117 1.00 71.62 ? 84 GLN G CB 1 +ATOM 12079 C CG . GLN G 1 84 ? 62.104 -24.246 45.541 1.00 58.66 ? 84 GLN G CG 1 +ATOM 12080 C CD . GLN G 1 84 ? 62.587 -25.627 45.908 1.00 64.62 ? 84 GLN G CD 1 +ATOM 12081 O OE1 . GLN G 1 84 ? 63.788 -25.882 46.009 1.00 79.96 ? 84 GLN G OE1 1 +ATOM 12082 N NE2 . GLN G 1 84 ? 61.653 -26.524 46.169 1.00 90.91 ? 84 GLN G NE2 1 +ATOM 12083 N N . GLY G 1 85 ? 62.001 -20.681 47.950 1.00 100.66 ? 85 GLY G N 1 +ATOM 12084 C CA . GLY G 1 85 ? 61.087 -20.160 48.971 1.00 113.43 ? 85 GLY G CA 1 +ATOM 12085 C C . GLY G 1 85 ? 61.055 -18.646 49.056 1.00 110.86 ? 85 GLY G C 1 +ATOM 12086 O O . GLY G 1 85 ? 61.025 -18.091 50.155 1.00 124.59 ? 85 GLY G O 1 +ATOM 12087 N N . LEU G 1 86 ? 61.085 -17.963 47.908 1.00 97.84 ? 86 LEU G N 1 +ATOM 12088 C CA . LEU G 1 86 ? 61.371 -16.505 47.882 1.00 86.00 ? 86 LEU G CA 1 +ATOM 12089 C C . LEU G 1 86 ? 60.332 -15.717 48.662 1.00 86.64 ? 86 LEU G C 1 +ATOM 12090 O O . LEU G 1 86 ? 60.654 -14.729 49.323 1.00 64.87 ? 86 LEU G O 1 +ATOM 12091 C CB . LEU G 1 86 ? 61.418 -15.964 46.452 1.00 82.51 ? 86 LEU G CB 1 +ATOM 12092 C CG . LEU G 1 86 ? 61.483 -14.433 46.196 1.00 56.98 ? 86 LEU G CG 1 +ATOM 12093 C CD1 . LEU G 1 86 ? 62.718 -13.819 46.776 1.00 54.12 ? 86 LEU G CD1 1 +ATOM 12094 C CD2 . LEU G 1 86 ? 61.460 -14.183 44.693 1.00 70.08 ? 86 LEU G CD2 1 +ATOM 12095 N N . GLN G 1 87 ? 59.095 -16.204 48.639 1.00 96.68 ? 87 GLN G N 1 +ATOM 12096 C CA . GLN G 1 87 ? 58.007 -15.491 49.298 1.00 109.77 ? 87 GLN G CA 1 +ATOM 12097 C C . GLN G 1 87 ? 58.248 -15.331 50.827 1.00 104.09 ? 87 GLN G C 1 +ATOM 12098 O O . GLN G 1 87 ? 58.048 -14.248 51.408 1.00 123.56 ? 87 GLN G O 1 +ATOM 12099 C CB . GLN G 1 87 ? 56.675 -16.186 48.998 1.00 107.73 ? 87 GLN G CB 1 +ATOM 12100 C CG . GLN G 1 87 ? 55.500 -15.225 48.871 1.00 119.53 ? 87 GLN G CG 1 +ATOM 12101 C CD . GLN G 1 87 ? 55.820 -13.968 48.065 1.00 139.77 ? 87 GLN G CD 1 +ATOM 12102 O OE1 . GLN G 1 87 ? 56.242 -14.041 46.905 1.00 177.39 ? 87 GLN G OE1 1 +ATOM 12103 N NE2 . GLN G 1 87 ? 55.611 -12.802 48.674 1.00 146.11 ? 87 GLN G NE2 1 +ATOM 12104 N N . ASN G 1 88 ? 58.698 -16.406 51.468 1.00 68.71 ? 88 ASN G N 1 +ATOM 12105 C CA . ASN G 1 88 ? 58.955 -16.386 52.893 1.00 49.52 ? 88 ASN G CA 1 +ATOM 12106 C C . ASN G 1 88 ? 60.069 -15.421 53.161 1.00 47.30 ? 88 ASN G C 1 +ATOM 12107 O O . ASN G 1 88 ? 60.174 -14.837 54.264 1.00 70.36 ? 88 ASN G O 1 +ATOM 12108 C CB . ASN G 1 88 ? 59.355 -17.768 53.388 1.00 61.43 ? 88 ASN G CB 1 +ATOM 12109 C CG . ASN G 1 88 ? 58.294 -18.793 53.166 1.00 74.51 ? 88 ASN G CG 1 +ATOM 12110 O OD1 . ASN G 1 88 ? 57.109 -18.459 53.188 1.00 67.39 ? 88 ASN G OD1 1 +ATOM 12111 N ND2 . ASN G 1 88 ? 58.707 -20.036 52.796 1.00 86.12 ? 88 ASN G ND2 1 +ATOM 12112 N N . LEU G 1 89 ? 61.005 -15.352 52.230 1.00 52.52 ? 89 LEU G N 1 +ATOM 12113 C CA . LEU G 1 89 ? 62.247 -14.614 52.470 1.00 98.91 ? 89 LEU G CA 1 +ATOM 12114 C C . LEU G 1 89 ? 61.834 -13.140 52.532 1.00 97.11 ? 89 LEU G C 1 +ATOM 12115 O O . LEU G 1 89 ? 62.286 -12.373 53.406 1.00 85.51 ? 89 LEU G O 1 +ATOM 12116 C CB . LEU G 1 89 ? 63.258 -14.910 51.334 1.00 102.58 ? 89 LEU G CB 1 +ATOM 12117 C CG . LEU G 1 89 ? 64.772 -14.779 51.564 1.00 81.93 ? 89 LEU G CG 1 +ATOM 12118 C CD1 . LEU G 1 89 ? 65.295 -13.639 50.723 1.00 83.05 ? 89 LEU G CD1 1 +ATOM 12119 C CD2 . LEU G 1 89 ? 65.111 -14.530 53.021 1.00 78.80 ? 89 LEU G CD2 1 +ATOM 12120 N N . LEU G 1 90 ? 60.911 -12.792 51.647 1.00 81.55 ? 90 LEU G N 1 +ATOM 12121 C CA . LEU G 1 90 ? 60.460 -11.407 51.543 1.00 85.98 ? 90 LEU G CA 1 +ATOM 12122 C C . LEU G 1 90 ? 59.599 -11.041 52.759 1.00 87.02 ? 90 LEU G C 1 +ATOM 12123 O O . LEU G 1 90 ? 59.582 -9.893 53.197 1.00 94.49 ? 90 LEU G O 1 +ATOM 12124 C CB . LEU G 1 90 ? 59.680 -11.213 50.251 1.00 77.25 ? 90 LEU G CB 1 +ATOM 12125 C CG . LEU G 1 90 ? 60.462 -11.494 48.983 1.00 77.07 ? 90 LEU G CG 1 +ATOM 12126 C CD1 . LEU G 1 90 ? 59.520 -11.735 47.829 1.00 72.46 ? 90 LEU G CD1 1 +ATOM 12127 C CD2 . LEU G 1 90 ? 61.392 -10.325 48.722 1.00 100.87 ? 90 LEU G CD2 1 +ATOM 12128 N N . ASN G 1 91 ? 58.901 -12.036 53.303 1.00 69.83 ? 91 ASN G N 1 +ATOM 12129 C CA . ASN G 1 91 ? 58.097 -11.847 54.499 1.00 54.79 ? 91 ASN G CA 1 +ATOM 12130 C C . ASN G 1 91 ? 58.920 -11.595 55.723 1.00 62.34 ? 91 ASN G C 1 +ATOM 12131 O O . ASN G 1 91 ? 58.673 -10.648 56.450 1.00 74.07 ? 91 ASN G O 1 +ATOM 12132 C CB . ASN G 1 91 ? 57.230 -13.046 54.730 1.00 73.89 ? 91 ASN G CB 1 +ATOM 12133 C CG . ASN G 1 91 ? 55.806 -12.636 54.907 1.00 118.25 ? 91 ASN G CG 1 +ATOM 12134 O OD1 . ASN G 1 91 ? 55.272 -11.944 54.031 1.00 186.79 ? 91 ASN G OD1 1 +ATOM 12135 N ND2 . ASN G 1 91 ? 55.214 -12.919 56.075 1.00 138.30 ? 91 ASN G ND2 1 +ATOM 12136 N N . GLU G 1 92 ? 59.954 -12.417 55.935 1.00 97.00 ? 92 GLU G N 1 +ATOM 12137 C CA . GLU G 1 92 ? 60.900 -12.201 57.048 1.00 90.07 ? 92 GLU G CA 1 +ATOM 12138 C C . GLU G 1 92 ? 61.591 -10.832 56.964 1.00 73.55 ? 92 GLU G C 1 +ATOM 12139 O O . GLU G 1 92 ? 61.749 -10.131 57.983 1.00 48.75 ? 92 GLU G O 1 +ATOM 12140 C CB . GLU G 1 92 ? 61.979 -13.280 57.102 1.00 69.30 ? 92 GLU G CB 1 +ATOM 12141 C CG . GLU G 1 92 ? 61.620 -14.478 57.960 1.00 66.39 ? 92 GLU G CG 1 +ATOM 12142 C CD . GLU G 1 92 ? 61.150 -14.110 59.377 1.00 81.20 ? 92 GLU G CD 1 +ATOM 12143 O OE1 . GLU G 1 92 ? 61.917 -13.426 60.160 1.00 95.36 ? 92 GLU G OE1 1 +ATOM 12144 O OE2 . GLU G 1 92 ? 60.001 -14.517 59.716 1.00 66.36 ? 92 GLU G OE2 1 +ATOM 12145 N N . ARG G 1 93 ? 61.883 -10.414 55.742 1.00 58.23 ? 93 ARG G N 1 +ATOM 12146 C CA . ARG G 1 93 ? 62.391 -9.078 55.536 1.00 73.19 ? 93 ARG G CA 1 +ATOM 12147 C C . ARG G 1 93 ? 61.354 -7.952 55.840 1.00 78.21 ? 93 ARG G C 1 +ATOM 12148 O O . ARG G 1 93 ? 61.703 -6.887 56.365 1.00 54.58 ? 93 ARG G O 1 +ATOM 12149 C CB . ARG G 1 93 ? 62.972 -8.979 54.124 1.00 79.10 ? 93 ARG G CB 1 +ATOM 12150 C CG . ARG G 1 93 ? 64.207 -9.853 53.960 1.00 72.87 ? 93 ARG G CG 1 +ATOM 12151 C CD . ARG G 1 93 ? 64.622 -10.089 52.512 1.00 66.25 ? 93 ARG G CD 1 +ATOM 12152 N NE . ARG G 1 93 ? 65.755 -9.257 52.127 1.00 61.43 ? 93 ARG G NE 1 +ATOM 12153 C CZ . ARG G 1 93 ? 65.659 -8.115 51.471 1.00 78.32 ? 93 ARG G CZ 1 +ATOM 12154 N NH1 . ARG G 1 93 ? 64.472 -7.613 51.109 1.00 110.51 ? 93 ARG G NH1 1 +ATOM 12155 N NH2 . ARG G 1 93 ? 66.758 -7.467 51.154 1.00 81.02 ? 93 ARG G NH2 1 +ATOM 12156 N N . LYS G 1 94 ? 60.074 -8.205 55.573 1.00 81.81 ? 94 LYS G N 1 +ATOM 12157 C CA . LYS G 1 94 ? 59.020 -7.261 55.985 1.00 86.11 ? 94 LYS G CA 1 +ATOM 12158 C C . LYS G 1 94 ? 58.977 -7.133 57.511 1.00 80.55 ? 94 LYS G C 1 +ATOM 12159 O O . LYS G 1 94 ? 58.820 -6.028 58.044 1.00 63.89 ? 94 LYS G O 1 +ATOM 12160 C CB . LYS G 1 94 ? 57.648 -7.725 55.504 1.00 93.15 ? 94 LYS G CB 1 +ATOM 12161 C CG . LYS G 1 94 ? 57.246 -7.274 54.109 1.00 104.66 ? 94 LYS G CG 1 +ATOM 12162 C CD . LYS G 1 94 ? 55.957 -7.974 53.694 1.00 107.91 ? 94 LYS G CD 1 +ATOM 12163 C CE . LYS G 1 94 ? 55.234 -7.262 52.565 1.00 114.95 ? 94 LYS G CE 1 +ATOM 12164 N NZ . LYS G 1 94 ? 54.197 -8.160 51.983 1.00 136.14 ? 94 LYS G NZ 1 +ATOM 12165 N N . ILE G 1 95 ? 59.133 -8.271 58.199 1.00 69.87 ? 95 ILE G N 1 +ATOM 12166 C CA . ILE G 1 95 ? 59.017 -8.301 59.650 1.00 66.36 ? 95 ILE G CA 1 +ATOM 12167 C C . ILE G 1 95 ? 60.210 -7.625 60.314 1.00 85.03 ? 95 ILE G C 1 +ATOM 12168 O O . ILE G 1 95 ? 60.033 -6.852 61.299 1.00 81.99 ? 95 ILE G O 1 +ATOM 12169 C CB . ILE G 1 95 ? 58.916 -9.707 60.237 1.00 52.06 ? 95 ILE G CB 1 +ATOM 12170 C CG1 . ILE G 1 95 ? 57.870 -10.521 59.510 1.00 69.31 ? 95 ILE G CG1 1 +ATOM 12171 C CG2 . ILE G 1 95 ? 58.490 -9.575 61.682 1.00 60.48 ? 95 ILE G CG2 1 +ATOM 12172 C CD1 . ILE G 1 95 ? 57.440 -11.790 60.206 1.00 82.88 ? 95 ILE G CD1 1 +ATOM 12173 N N . ILE G 1 96 ? 61.391 -7.879 59.739 1.00 76.33 ? 96 ILE G N 1 +ATOM 12174 C CA . ILE G 1 96 ? 62.580 -7.132 60.088 1.00 78.75 ? 96 ILE G CA 1 +ATOM 12175 C C . ILE G 1 96 ? 62.342 -5.629 59.952 1.00 90.91 ? 96 ILE G C 1 +ATOM 12176 O O . ILE G 1 96 ? 62.489 -4.882 60.929 1.00 118.30 ? 96 ILE G O 1 +ATOM 12177 C CB . ILE G 1 96 ? 63.798 -7.520 59.230 1.00 74.54 ? 96 ILE G CB 1 +ATOM 12178 C CG1 . ILE G 1 96 ? 64.176 -8.960 59.506 1.00 91.86 ? 96 ILE G CG1 1 +ATOM 12179 C CG2 . ILE G 1 96 ? 64.991 -6.632 59.577 1.00 63.62 ? 96 ILE G CG2 1 +ATOM 12180 C CD1 . ILE G 1 96 ? 65.413 -9.400 58.754 1.00 123.27 ? 96 ILE G CD1 1 +ATOM 12181 N N . ARG G 1 97 ? 62.006 -5.179 58.744 1.00 79.23 ? 97 ARG G N 1 +ATOM 12182 C CA . ARG G 1 97 ? 61.884 -3.745 58.480 1.00 89.97 ? 97 ARG G CA 1 +ATOM 12183 C C . ARG G 1 97 ? 60.820 -3.106 59.374 1.00 100.92 ? 97 ARG G C 1 +ATOM 12184 O O . ARG G 1 97 ? 60.925 -1.922 59.738 1.00 120.66 ? 97 ARG G O 1 +ATOM 12185 C CB . ARG G 1 97 ? 61.551 -3.483 57.012 1.00 97.74 ? 97 ARG G CB 1 +ATOM 12186 C CG . ARG G 1 97 ? 62.716 -2.983 56.178 1.00 103.36 ? 97 ARG G CG 1 +ATOM 12187 C CD . ARG G 1 97 ? 62.273 -2.684 54.753 1.00 108.17 ? 97 ARG G CD 1 +ATOM 12188 N NE . ARG G 1 97 ? 62.196 -3.898 53.942 1.00 92.50 ? 97 ARG G NE 1 +ATOM 12189 C CZ . ARG G 1 97 ? 63.148 -4.293 53.092 1.00 116.52 ? 97 ARG G CZ 1 +ATOM 12190 N NH1 . ARG G 1 97 ? 64.290 -3.600 52.931 1.00 111.78 ? 97 ARG G NH1 1 +ATOM 12191 N NH2 . ARG G 1 97 ? 62.968 -5.402 52.397 1.00 147.41 ? 97 ARG G NH2 1 +ATOM 12192 N N . ALA G 1 98 ? 59.784 -3.873 59.707 1.00 75.41 ? 98 ALA G N 1 +ATOM 12193 C CA . ALA G 1 98 ? 58.753 -3.373 60.587 1.00 72.71 ? 98 ALA G CA 1 +ATOM 12194 C C . ALA G 1 98 ? 59.259 -3.254 62.029 1.00 90.11 ? 98 ALA G C 1 +ATOM 12195 O O . ALA G 1 98 ? 58.791 -2.413 62.818 1.00 74.51 ? 98 ALA G O 1 +ATOM 12196 C CB . ALA G 1 98 ? 57.551 -4.272 60.508 1.00 59.30 ? 98 ALA G CB 1 +ATOM 12197 N N . ALA G 1 99 ? 60.218 -4.110 62.364 1.00 111.35 ? 99 ALA G N 1 +ATOM 12198 C CA . ALA G 1 99 ? 60.775 -4.146 63.708 1.00 107.31 ? 99 ALA G CA 1 +ATOM 12199 C C . ALA G 1 99 ? 61.582 -2.888 63.991 1.00 61.25 ? 99 ALA G C 1 +ATOM 12200 O O . ALA G 1 99 ? 61.457 -2.279 65.042 1.00 32.60 ? 99 ALA G O 1 +ATOM 12201 C CB . ALA G 1 99 ? 61.626 -5.419 63.901 1.00 134.59 ? 99 ALA G CB 1 +ATOM 12202 N N . GLN G 1 100 ? 62.485 -2.581 63.074 1.00 64.60 ? 100 GLN G N 1 +ATOM 12203 C CA . GLN G 1 100 ? 63.615 -1.693 63.390 1.00 107.67 ? 100 GLN G CA 1 +ATOM 12204 C C . GLN G 1 100 ? 63.497 -0.337 62.724 1.00 101.39 ? 100 GLN G C 1 +ATOM 12205 O O . GLN G 1 100 ? 64.404 0.498 62.836 1.00 85.66 ? 100 GLN G O 1 +ATOM 12206 C CB . GLN G 1 100 ? 64.979 -2.329 63.029 1.00 120.82 ? 100 GLN G CB 1 +ATOM 12207 C CG . GLN G 1 100 ? 65.016 -3.064 61.701 1.00 106.31 ? 100 GLN G CG 1 +ATOM 12208 C CD . GLN G 1 100 ? 66.045 -4.191 61.644 1.00 96.27 ? 100 GLN G CD 1 +ATOM 12209 O OE1 . GLN G 1 100 ? 66.028 -5.153 62.445 1.00 52.81 ? 100 GLN G OE1 1 +ATOM 12210 N NE2 . GLN G 1 100 ? 66.953 -4.071 60.686 1.00 101.73 ? 100 GLN G NE2 1 +ATOM 12211 N N . GLU G 1 101 ? 62.349 -0.093 62.099 1.00 101.00 ? 101 GLU G N 1 +ATOM 12212 C CA . GLU G 1 101 ? 62.112 1.194 61.432 1.00 106.27 ? 101 GLU G CA 1 +ATOM 12213 C C . GLU G 1 101 ? 62.045 2.403 62.389 1.00 92.20 ? 101 GLU G C 1 +ATOM 12214 O O . GLU G 1 101 ? 62.291 3.522 61.985 1.00 86.95 ? 101 GLU G O 1 +ATOM 12215 C CB . GLU G 1 101 ? 60.852 1.119 60.563 1.00 99.76 ? 101 GLU G CB 1 +ATOM 12216 C CG . GLU G 1 101 ? 59.606 0.639 61.291 1.00 105.42 ? 101 GLU G CG 1 +ATOM 12217 C CD . GLU G 1 101 ? 58.369 0.657 60.410 1.00 110.18 ? 101 GLU G CD 1 +ATOM 12218 O OE1 . GLU G 1 101 ? 58.528 0.724 59.171 1.00 134.55 ? 101 GLU G OE1 1 +ATOM 12219 O OE2 . GLU G 1 101 ? 57.237 0.612 60.943 1.00 89.34 ? 101 GLU G OE2 1 +ATOM 12220 N N . ASN G 1 102 ? 61.717 2.166 63.650 1.00 80.72 ? 102 ASN G N 1 +ATOM 12221 C CA . ASN G 1 102 ? 61.551 3.251 64.596 1.00 64.65 ? 102 ASN G CA 1 +ATOM 12222 C C . ASN G 1 102 ? 62.817 3.565 65.356 1.00 78.35 ? 102 ASN G C 1 +ATOM 12223 O O . ASN G 1 102 ? 62.823 4.427 66.236 1.00 107.02 ? 102 ASN G O 1 +ATOM 12224 C CB . ASN G 1 102 ? 60.415 2.918 65.556 1.00 62.11 ? 102 ASN G CB 1 +ATOM 12225 C CG . ASN G 1 102 ? 59.085 3.010 64.879 1.00 80.15 ? 102 ASN G CG 1 +ATOM 12226 O OD1 . ASN G 1 102 ? 58.546 4.107 64.658 1.00 106.09 ? 102 ASN G OD1 1 +ATOM 12227 N ND2 . ASN G 1 102 ? 58.545 1.856 64.501 1.00 103.78 ? 102 ASN G ND2 1 +ATOM 12228 N N . GLY G 1 103 ? 63.868 2.783 65.133 1.00 93.20 ? 103 GLY G N 1 +ATOM 12229 C CA . GLY G 1 103 ? 65.108 2.943 65.923 1.00 120.06 ? 103 GLY G CA 1 +ATOM 12230 C C . GLY G 1 103 ? 64.986 2.802 67.447 1.00 90.47 ? 103 GLY G C 1 +ATOM 12231 O O . GLY G 1 103 ? 65.655 3.476 68.208 1.00 81.25 ? 103 GLY G O 1 +ATOM 12232 N N . THR G 1 104 ? 64.119 1.911 67.873 1.00 93.61 ? 104 THR G N 1 +ATOM 12233 C CA . THR G 1 104 ? 64.088 1.508 69.240 1.00 101.26 ? 104 THR G CA 1 +ATOM 12234 C C . THR G 1 104 ? 64.800 0.183 69.386 1.00 98.70 ? 104 THR G C 1 +ATOM 12235 O O . THR G 1 104 ? 65.333 -0.091 70.449 1.00 130.99 ? 104 THR G O 1 +ATOM 12236 C CB . THR G 1 104 ? 62.637 1.405 69.782 1.00 139.34 ? 104 THR G CB 1 +ATOM 12237 O OG1 . THR G 1 104 ? 61.895 0.371 69.115 1.00 130.32 ? 104 THR G OG1 1 +ATOM 12238 C CG2 . THR G 1 104 ? 61.905 2.741 69.608 1.00 158.30 ? 104 THR G CG2 1 +ATOM 12239 N N . VAL G 1 105 ? 64.786 -0.652 68.350 1.00 91.55 ? 105 VAL G N 1 +ATOM 12240 C CA . VAL G 1 105 ? 65.292 -2.006 68.487 1.00 108.01 ? 105 VAL G CA 1 +ATOM 12241 C C . VAL G 1 105 ? 66.754 -1.992 68.966 1.00 134.60 ? 105 VAL G C 1 +ATOM 12242 O O . VAL G 1 105 ? 67.584 -1.183 68.521 1.00 138.13 ? 105 VAL G O 1 +ATOM 12243 C CB . VAL G 1 105 ? 65.117 -2.866 67.200 1.00 132.01 ? 105 VAL G CB 1 +ATOM 12244 C CG1 . VAL G 1 105 ? 66.260 -3.881 67.014 1.00 168.95 ? 105 VAL G CG1 1 +ATOM 12245 C CG2 . VAL G 1 105 ? 63.784 -3.612 67.216 1.00 119.76 ? 105 VAL G CG2 1 +ATOM 12246 N N . ALA G 1 106 ? 67.053 -2.932 69.866 1.00 139.89 ? 106 ALA G N 1 +ATOM 12247 C CA . ALA G 1 106 ? 68.337 -3.016 70.544 1.00 117.95 ? 106 ALA G CA 1 +ATOM 12248 C C . ALA G 1 106 ? 69.472 -3.222 69.540 1.00 106.36 ? 106 ALA G C 1 +ATOM 12249 O O . ALA G 1 106 ? 69.407 -4.106 68.680 1.00 112.22 ? 106 ALA G O 1 +ATOM 12250 C CB . ALA G 1 106 ? 68.303 -4.148 71.582 1.00 111.31 ? 106 ALA G CB 1 +ATOM 12251 N N . ILE G 1 107 ? 70.535 -2.447 69.697 1.00 104.27 ? 107 ILE G N 1 +ATOM 12252 C CA . ILE G 1 107 ? 71.648 -2.521 68.755 1.00 110.85 ? 107 ILE G CA 1 +ATOM 12253 C C . ILE G 1 107 ? 72.313 -3.899 68.605 1.00 120.17 ? 107 ILE G C 1 +ATOM 12254 O O . ILE G 1 107 ? 72.848 -4.214 67.551 1.00 112.85 ? 107 ILE G O 1 +ATOM 12255 C CB . ILE G 1 107 ? 72.672 -1.406 68.870 1.00 109.49 ? 107 ILE G CB 1 +ATOM 12256 C CG1 . ILE G 1 107 ? 72.540 -0.644 70.184 1.00 115.07 ? 107 ILE G CG1 1 +ATOM 12257 C CG2 . ILE G 1 107 ? 72.455 -0.494 67.664 1.00 98.60 ? 107 ILE G CG2 1 +ATOM 12258 C CD1 . ILE G 1 107 ? 72.842 -1.421 71.468 1.00 102.88 ? 107 ILE G CD1 1 +ATOM 12259 N N . ASN G 1 108 ? 72.296 -4.690 69.676 1.00 129.69 ? 108 ASN G N 1 +ATOM 12260 C CA . ASN G 1 108 ? 72.774 -6.077 69.633 1.00 142.43 ? 108 ASN G CA 1 +ATOM 12261 C C . ASN G 1 108 ? 71.843 -6.956 68.801 1.00 139.99 ? 108 ASN G C 1 +ATOM 12262 O O . ASN G 1 108 ? 72.290 -7.874 68.108 1.00 175.08 ? 108 ASN G O 1 +ATOM 12263 C CB . ASN G 1 108 ? 72.858 -6.669 71.043 1.00 143.48 ? 108 ASN G CB 1 +ATOM 12264 C CG . ASN G 1 108 ? 73.163 -5.626 72.095 1.00 163.46 ? 108 ASN G CG 1 +ATOM 12265 O OD1 . ASN G 1 108 ? 74.325 -5.314 72.357 1.00 222.41 ? 108 ASN G OD1 1 +ATOM 12266 N ND2 . ASN G 1 108 ? 72.119 -5.069 72.697 1.00 170.27 ? 108 ASN G ND2 1 +ATOM 12267 N N . ASN G 1 109 ? 70.552 -6.659 68.879 1.00 103.97 ? 109 ASN G N 1 +ATOM 12268 C CA . ASN G 1 109 ? 69.536 -7.461 68.234 1.00 103.91 ? 109 ASN G CA 1 +ATOM 12269 C C . ASN G 1 109 ? 69.302 -7.072 66.770 1.00 102.48 ? 109 ASN G C 1 +ATOM 12270 O O . ASN G 1 109 ? 68.691 -7.832 65.996 1.00 144.89 ? 109 ASN G O 1 +ATOM 12271 C CB . ASN G 1 109 ? 68.233 -7.345 69.023 1.00 123.92 ? 109 ASN G CB 1 +ATOM 12272 C CG . ASN G 1 109 ? 67.803 -8.662 69.617 1.00 148.83 ? 109 ASN G CG 1 +ATOM 12273 O OD1 . ASN G 1 109 ? 66.775 -9.219 69.229 1.00 192.57 ? 109 ASN G OD1 1 +ATOM 12274 N ND2 . ASN G 1 109 ? 68.611 -9.198 70.525 1.00 152.76 ? 109 ASN G ND2 1 +ATOM 12275 N N . ARG G 1 110 ? 69.765 -5.877 66.402 1.00 89.18 ? 110 ARG G N 1 +ATOM 12276 C CA . ARG G 1 110 ? 69.484 -5.265 65.087 1.00 78.52 ? 110 ARG G CA 1 +ATOM 12277 C C . ARG G 1 110 ? 69.930 -6.172 63.930 1.00 71.98 ? 110 ARG G C 1 +ATOM 12278 O O . ARG G 1 110 ? 71.031 -6.728 63.972 1.00 111.56 ? 110 ARG G O 1 +ATOM 12279 C CB . ARG G 1 110 ? 70.225 -3.920 64.993 1.00 78.65 ? 110 ARG G CB 1 +ATOM 12280 C CG . ARG G 1 110 ? 69.652 -2.943 63.989 1.00 88.99 ? 110 ARG G CG 1 +ATOM 12281 C CD . ARG G 1 110 ? 69.820 -1.507 64.444 1.00 110.14 ? 110 ARG G CD 1 +ATOM 12282 N NE . ARG G 1 110 ? 71.095 -0.967 63.959 1.00 111.17 ? 110 ARG G NE 1 +ATOM 12283 C CZ . ARG G 1 110 ? 71.225 0.097 63.164 1.00 133.61 ? 110 ARG G CZ 1 +ATOM 12284 N NH1 . ARG G 1 110 ? 70.155 0.784 62.735 1.00 152.35 ? 110 ARG G NH1 1 +ATOM 12285 N NH2 . ARG G 1 110 ? 72.439 0.495 62.798 1.00 116.33 ? 110 ARG G NH2 1 +ATOM 12286 N N . ILE G 1 111 ? 69.092 -6.325 62.909 1.00 59.01 ? 111 ILE G N 1 +ATOM 12287 C CA . ILE G 1 111 ? 69.489 -7.059 61.714 1.00 65.68 ? 111 ILE G CA 1 +ATOM 12288 C C . ILE G 1 111 ? 69.670 -6.110 60.563 1.00 84.56 ? 111 ILE G C 1 +ATOM 12289 O O . ILE G 1 111 ? 68.703 -5.497 60.127 1.00 101.00 ? 111 ILE G O 1 +ATOM 12290 C CB . ILE G 1 111 ? 68.452 -8.099 61.305 1.00 84.31 ? 111 ILE G CB 1 +ATOM 12291 C CG1 . ILE G 1 111 ? 68.341 -9.174 62.403 1.00 103.69 ? 111 ILE G CG1 1 +ATOM 12292 C CG2 . ILE G 1 111 ? 68.845 -8.747 59.980 1.00 97.17 ? 111 ILE G CG2 1 +ATOM 12293 C CD1 . ILE G 1 111 ? 67.151 -10.129 62.265 1.00 75.84 ? 111 ILE G CD1 1 +ATOM 12294 N N . PRO G 1 112 ? 70.917 -5.972 60.061 1.00 106.33 ? 112 PRO G N 1 +ATOM 12295 C CA . PRO G 1 112 ? 71.170 -5.062 58.954 1.00 95.67 ? 112 PRO G CA 1 +ATOM 12296 C C . PRO G 1 112 ? 70.699 -5.658 57.611 1.00 107.51 ? 112 PRO G C 1 +ATOM 12297 O O . PRO G 1 112 ? 71.048 -6.798 57.259 1.00 84.69 ? 112 PRO G O 1 +ATOM 12298 C CB . PRO G 1 112 ? 72.681 -4.904 58.986 1.00 87.79 ? 112 PRO G CB 1 +ATOM 12299 C CG . PRO G 1 112 ? 73.176 -6.233 59.461 1.00 99.70 ? 112 PRO G CG 1 +ATOM 12300 C CD . PRO G 1 112 ? 72.093 -6.822 60.334 1.00 113.66 ? 112 PRO G CD 1 +ATOM 12301 N N . LEU G 1 113 ? 69.892 -4.884 56.887 1.00 104.76 ? 113 LEU G N 1 +ATOM 12302 C CA . LEU G 1 113 ? 69.270 -5.343 55.654 1.00 81.89 ? 113 LEU G CA 1 +ATOM 12303 C C . LEU G 1 113 ? 69.896 -4.685 54.435 1.00 78.59 ? 113 LEU G C 1 +ATOM 12304 O O . LEU G 1 113 ? 70.203 -3.478 54.427 1.00 82.16 ? 113 LEU G O 1 +ATOM 12305 C CB . LEU G 1 113 ? 67.764 -5.056 55.662 1.00 64.76 ? 113 LEU G CB 1 +ATOM 12306 C CG . LEU G 1 113 ? 66.922 -6.124 56.334 1.00 62.30 ? 113 LEU G CG 1 +ATOM 12307 C CD1 . LEU G 1 113 ? 65.492 -5.715 56.134 1.00 85.88 ? 113 LEU G CD1 1 +ATOM 12308 C CD2 . LEU G 1 113 ? 67.137 -7.519 55.757 1.00 61.63 ? 113 LEU G CD2 1 +ATOM 12309 N N . GLN G 1 114 ? 69.953 -5.448 53.363 1.00 67.58 ? 114 GLN G N 1 +ATOM 12310 C CA . GLN G 1 114 ? 70.259 -4.846 52.080 1.00 83.83 ? 114 GLN G CA 1 +ATOM 12311 C C . GLN G 1 114 ? 69.420 -5.603 51.097 1.00 91.67 ? 114 GLN G C 1 +ATOM 12312 O O . GLN G 1 114 ? 69.213 -6.806 51.265 1.00 147.21 ? 114 GLN G O 1 +ATOM 12313 C CB . GLN G 1 114 ? 71.736 -4.974 51.731 1.00 104.24 ? 114 GLN G CB 1 +ATOM 12314 C CG . GLN G 1 114 ? 72.269 -3.919 50.769 1.00 100.48 ? 114 GLN G CG 1 +ATOM 12315 C CD . GLN G 1 114 ? 73.174 -4.544 49.734 1.00 116.48 ? 114 GLN G CD 1 +ATOM 12316 O OE1 . GLN G 1 114 ? 73.025 -4.262 48.557 1.00 68.98 ? 114 GLN G OE1 1 +ATOM 12317 N NE2 . GLN G 1 114 ? 74.005 -5.516 50.154 1.00 150.66 ? 114 GLN G NE2 1 +ATOM 12318 N N . SER G 1 115 ? 68.980 -4.923 50.049 1.00 101.37 ? 115 SER G N 1 +ATOM 12319 C CA . SER G 1 115 ? 68.188 -5.559 49.006 1.00 99.52 ? 115 SER G CA 1 +ATOM 12320 C C . SER G 1 115 ? 69.004 -6.801 48.501 1.00 70.27 ? 115 SER G C 1 +ATOM 12321 O O . SER G 1 115 ? 70.140 -6.817 48.460 1.00 39.11 ? 115 SER G O 1 +ATOM 12322 C CB . SER G 1 115 ? 67.800 -4.513 47.915 1.00 85.61 ? 115 SER G CB 1 +ATOM 12323 O OG . SER G 1 115 ? 68.944 -3.903 47.380 1.00 115.65 ? 115 SER G OG 1 +ATOM 12324 N N . LEU G 1 116 ? 68.331 -7.733 47.927 1.00 67.75 ? 116 LEU G N 1 +ATOM 12325 C CA . LEU G 1 116 ? 68.675 -9.125 47.775 1.00 64.61 ? 116 LEU G CA 1 +ATOM 12326 C C . LEU G 1 116 ? 69.806 -9.280 46.770 1.00 69.09 ? 116 LEU G C 1 +ATOM 12327 O O . LEU G 1 116 ? 69.682 -8.863 45.618 1.00 83.64 ? 116 LEU G O 1 +ATOM 12328 C CB . LEU G 1 116 ? 67.386 -9.854 47.302 1.00 75.21 ? 116 LEU G CB 1 +ATOM 12329 C CG . LEU G 1 116 ? 66.211 -9.790 48.294 1.00 76.76 ? 116 LEU G CG 1 +ATOM 12330 C CD1 . LEU G 1 116 ? 65.282 -8.587 48.013 1.00 76.25 ? 116 LEU G CD1 1 +ATOM 12331 C CD2 . LEU G 1 116 ? 65.436 -11.100 48.228 1.00 70.72 ? 116 LEU G CD2 1 +ATOM 12332 N N . THR G 1 117 ? 70.784 -10.101 47.126 1.00 85.24 ? 117 THR G N 1 +ATOM 12333 C CA . THR G 1 117 ? 71.828 -10.510 46.190 1.00 111.94 ? 117 THR G CA 1 +ATOM 12334 C C . THR G 1 117 ? 71.234 -11.131 44.935 1.00 102.95 ? 117 THR G C 1 +ATOM 12335 O O . THR G 1 117 ? 70.390 -12.023 45.013 1.00 85.94 ? 117 THR G O 1 +ATOM 12336 C CB . THR G 1 117 ? 72.801 -11.556 46.799 1.00 144.95 ? 117 THR G CB 1 +ATOM 12337 O OG1 . THR G 1 117 ? 73.280 -11.097 48.063 1.00 160.37 ? 117 THR G OG1 1 +ATOM 12338 C CG2 . THR G 1 117 ? 73.997 -11.768 45.889 1.00 166.58 ? 117 THR G CG2 1 +ATOM 12339 N N . ALA G 1 118 ? 71.713 -10.681 43.778 1.00 127.79 ? 118 ALA G N 1 +ATOM 12340 C CA . ALA G 1 118 ? 71.090 -11.021 42.500 1.00 108.04 ? 118 ALA G CA 1 +ATOM 12341 C C . ALA G 1 118 ? 72.030 -11.856 41.662 1.00 69.55 ? 118 ALA G C 1 +ATOM 12342 O O . ALA G 1 118 ? 73.189 -11.517 41.483 1.00 55.43 ? 118 ALA G O 1 +ATOM 12343 C CB . ALA G 1 118 ? 70.663 -9.753 41.752 1.00 106.96 ? 118 ALA G CB 1 +ATOM 12344 N N . ALA G 1 119 ? 71.439 -12.831 41.015 1.00 66.71 ? 119 ALA G N 1 +ATOM 12345 C CA . ALA G 1 119 ? 72.152 -13.732 40.154 1.00 80.77 ? 119 ALA G CA 1 +ATOM 12346 C C . ALA G 1 119 ? 72.435 -13.158 38.742 1.00 78.32 ? 119 ALA G C 1 +ATOM 12347 O O . ALA G 1 119 ? 71.631 -12.397 38.201 1.00 96.65 ? 119 ALA G O 1 +ATOM 12348 C CB . ALA G 1 119 ? 71.351 -15.028 40.059 1.00 94.53 ? 119 ALA G CB 1 +ATOM 12349 N N . ASN G 1 120 ? 73.463 -13.675 38.088 1.00 80.49 ? 120 ASN G N 1 +ATOM 12350 C CA . ASN G 1 120 ? 73.664 -13.379 36.686 1.00 81.32 ? 120 ASN G CA 1 +ATOM 12351 C C . ASN G 1 120 ? 73.114 -14.468 35.759 1.00 70.04 ? 120 ASN G C 1 +ATOM 12352 O O . ASN G 1 120 ? 72.566 -14.180 34.677 1.00 88.37 ? 120 ASN G O 1 +ATOM 12353 C CB . ASN G 1 120 ? 75.150 -13.159 36.392 1.00 102.48 ? 120 ASN G CB 1 +ATOM 12354 C CG . ASN G 1 120 ? 75.419 -12.787 34.929 1.00 132.52 ? 120 ASN G CG 1 +ATOM 12355 O OD1 . ASN G 1 120 ? 74.628 -12.082 34.264 1.00 85.48 ? 120 ASN G OD1 1 +ATOM 12356 N ND2 . ASN G 1 120 ? 76.536 -13.301 34.405 1.00 150.84 ? 120 ASN G ND2 1 +ATOM 12357 N N . ILE G 1 121 ? 73.439 -15.713 36.060 1.00 57.09 ? 121 ILE G N 1 +ATOM 12358 C CA . ILE G 1 121 ? 72.934 -16.787 35.255 1.00 62.95 ? 121 ILE G CA 1 +ATOM 12359 C C . ILE G 1 121 ? 71.933 -17.505 36.140 1.00 80.62 ? 121 ILE G C 1 +ATOM 12360 O O . ILE G 1 121 ? 72.165 -17.671 37.328 1.00 65.79 ? 121 ILE G O 1 +ATOM 12361 C CB . ILE G 1 121 ? 74.048 -17.751 34.720 1.00 58.83 ? 121 ILE G CB 1 +ATOM 12362 C CG1 . ILE G 1 121 ? 74.638 -18.645 35.835 1.00 51.97 ? 121 ILE G CG1 1 +ATOM 12363 C CG2 . ILE G 1 121 ? 75.143 -16.982 33.984 1.00 45.26 ? 121 ILE G CG2 1 +ATOM 12364 C CD1 . ILE G 1 121 ? 74.252 -20.116 35.724 1.00 55.00 ? 121 ILE G CD1 1 +ATOM 12365 N N . MET G 1 122 ? 70.828 -17.957 35.550 1.00 71.47 ? 122 MET G N 1 +ATOM 12366 C CA . MET G 1 122 ? 69.974 -18.891 36.258 1.00 54.22 ? 122 MET G CA 1 +ATOM 12367 C C . MET G 1 122 ? 69.782 -20.154 35.462 1.00 50.00 ? 122 MET G C 1 +ATOM 12368 O O . MET G 1 122 ? 69.901 -20.156 34.234 1.00 43.39 ? 122 MET G O 1 +ATOM 12369 C CB . MET G 1 122 ? 68.656 -18.238 36.556 1.00 67.59 ? 122 MET G CB 1 +ATOM 12370 C CG . MET G 1 122 ? 67.890 -17.716 35.347 1.00 77.13 ? 122 MET G CG 1 +ATOM 12371 S SD . MET G 1 122 ? 66.118 -17.727 35.682 1.00 105.60 ? 122 MET G SD 1 +ATOM 12372 C CE . MET G 1 122 ? 65.459 -18.370 34.143 1.00 52.57 ? 122 MET G CE 1 +ATOM 12373 N N . VAL G 1 123 ? 69.740 -21.271 36.166 1.00 63.46 ? 123 VAL G N 1 +ATOM 12374 C CA . VAL G 1 123 ? 69.722 -22.578 35.507 1.00 83.25 ? 123 VAL G CA 1 +ATOM 12375 C C . VAL G 1 123 ? 68.431 -23.251 35.887 1.00 88.39 ? 123 VAL G C 1 +ATOM 12376 O O . VAL G 1 123 ? 68.147 -23.445 37.054 1.00 61.61 ? 123 VAL G O 1 +ATOM 12377 C CB . VAL G 1 123 ? 70.916 -23.506 35.876 1.00 80.93 ? 123 VAL G CB 1 +ATOM 12378 C CG1 . VAL G 1 123 ? 71.260 -23.403 37.343 1.00 89.04 ? 123 VAL G CG1 1 +ATOM 12379 C CG2 . VAL G 1 123 ? 70.618 -24.963 35.511 1.00 98.06 ? 123 VAL G CG2 1 +ATOM 12380 N N . GLU G 1 124 ? 67.677 -23.653 34.873 1.00 106.64 ? 124 GLU G N 1 +ATOM 12381 C CA . GLU G 1 124 ? 66.492 -24.475 35.092 1.00 120.16 ? 124 GLU G CA 1 +ATOM 12382 C C . GLU G 1 124 ? 66.503 -25.705 34.213 1.00 118.69 ? 124 GLU G C 1 +ATOM 12383 O O . GLU G 1 124 ? 67.370 -25.869 33.364 1.00 139.11 ? 124 GLU G O 1 +ATOM 12384 C CB . GLU G 1 124 ? 65.227 -23.684 34.814 1.00 123.96 ? 124 GLU G CB 1 +ATOM 12385 C CG . GLU G 1 124 ? 65.373 -22.595 33.766 1.00 123.43 ? 124 GLU G CG 1 +ATOM 12386 C CD . GLU G 1 124 ? 64.261 -21.571 33.860 1.00 129.19 ? 124 GLU G CD 1 +ATOM 12387 O OE1 . GLU G 1 124 ? 63.790 -21.283 34.983 1.00 70.89 ? 124 GLU G OE1 1 +ATOM 12388 O OE2 . GLU G 1 124 ? 63.778 -21.148 32.789 1.00 207.40 ? 124 GLU G OE2 1 +ATOM 12389 N N . GLY G 1 125 ? 65.569 -26.605 34.476 1.00 105.97 ? 125 GLY G N 1 +ATOM 12390 C CA . GLY G 1 125 ? 65.567 -27.892 33.814 1.00 99.13 ? 125 GLY G CA 1 +ATOM 12391 C C . GLY G 1 125 ? 64.312 -28.674 34.096 1.00 100.68 ? 125 GLY G C 1 +ATOM 12392 O O . GLY G 1 125 ? 63.344 -28.149 34.648 1.00 108.85 ? 125 GLY G O 1 +ATOM 12393 N N . SER G 1 126 ? 64.364 -29.972 33.831 1.00 101.99 ? 126 SER G N 1 +ATOM 12394 C CA . SER G 1 126 ? 63.196 -30.821 34.034 1.00 101.03 ? 126 SER G CA 1 +ATOM 12395 C C . SER G 1 126 ? 63.595 -32.279 34.128 1.00 75.01 ? 126 SER G C 1 +ATOM 12396 O O . SER G 1 126 ? 64.601 -32.674 33.572 1.00 63.32 ? 126 SER G O 1 +ATOM 12397 C CB . SER G 1 126 ? 62.257 -30.678 32.853 1.00 131.19 ? 126 SER G CB 1 +ATOM 12398 O OG . SER G 1 126 ? 62.323 -29.378 32.271 1.00 173.50 ? 126 SER G OG 1 +ATOM 12399 N N . ILE G 1 127 ? 62.863 -33.052 34.916 1.00 65.31 ? 127 ILE G N 1 +ATOM 12400 C CA . ILE G 1 127 ? 63.003 -34.464 34.839 1.00 70.79 ? 127 ILE G CA 1 +ATOM 12401 C C . ILE G 1 127 ? 62.238 -34.831 33.576 1.00 90.58 ? 127 ILE G C 1 +ATOM 12402 O O . ILE G 1 127 ? 61.029 -34.995 33.577 1.00 75.84 ? 127 ILE G O 1 +ATOM 12403 C CB . ILE G 1 127 ? 62.466 -35.208 36.074 1.00 91.33 ? 127 ILE G CB 1 +ATOM 12404 C CG1 . ILE G 1 127 ? 63.329 -34.897 37.297 1.00 117.42 ? 127 ILE G CG1 1 +ATOM 12405 C CG2 . ILE G 1 127 ? 62.453 -36.726 35.846 1.00 121.46 ? 127 ILE G CG2 1 +ATOM 12406 C CD1 . ILE G 1 127 ? 62.561 -34.925 38.611 1.00 139.89 ? 127 ILE G CD1 1 +ATOM 12407 N N . ILE G 1 128 ? 62.997 -35.085 32.526 1.00 117.26 ? 128 ILE G N 1 +ATOM 12408 C CA . ILE G 1 128 ? 62.474 -35.610 31.300 1.00 109.83 ? 128 ILE G CA 1 +ATOM 12409 C C . ILE G 1 128 ? 62.487 -37.150 31.417 1.00 89.16 ? 128 ILE G C 1 +ATOM 12410 O O . ILE G 1 128 ? 63.527 -37.803 31.235 1.00 123.65 ? 128 ILE G O 1 +ATOM 12411 C CB . ILE G 1 128 ? 63.464 -35.378 30.141 1.00 125.85 ? 128 ILE G CB 1 +ATOM 12412 C CG1 . ILE G 1 128 ? 64.113 -33.986 30.005 1.00 113.40 ? 128 ILE G CG1 1 +ATOM 12413 C CG2 . ILE G 1 128 ? 62.754 -35.651 28.857 1.00 128.65 ? 128 ILE G CG2 1 +ATOM 12414 C CD1 . ILE G 1 128 ? 65.480 -34.078 29.328 1.00 127.94 ? 128 ILE G CD1 1 +ATOM 12415 N N . GLY G 1 129 ? 61.351 -37.734 31.715 1.00 59.20 ? 129 GLY G N 1 +ATOM 12416 C CA . GLY G 1 129 ? 61.154 -39.133 31.447 1.00 63.03 ? 129 GLY G CA 1 +ATOM 12417 C C . GLY G 1 129 ? 61.570 -40.049 32.574 1.00 78.84 ? 129 GLY G C 1 +ATOM 12418 O O . GLY G 1 129 ? 62.666 -39.959 33.142 1.00 76.77 ? 129 GLY G O 1 +ATOM 12419 N N . TYR G 1 130 ? 60.702 -41.023 32.826 1.00 131.53 ? 130 TYR G N 1 +ATOM 12420 C CA . TYR G 1 130 ? 61.050 -42.235 33.574 1.00 131.92 ? 130 TYR G CA 1 +ATOM 12421 C C . TYR G 1 130 ? 60.343 -43.387 32.899 1.00 127.08 ? 130 TYR G C 1 +ATOM 12422 O O . TYR G 1 130 ? 59.119 -43.448 32.907 1.00 144.63 ? 130 TYR G O 1 +ATOM 12423 C CB . TYR G 1 130 ? 60.590 -42.109 35.031 1.00 121.70 ? 130 TYR G CB 1 +ATOM 12424 C CG . TYR G 1 130 ? 60.767 -43.338 35.894 1.00 113.32 ? 130 TYR G CG 1 +ATOM 12425 C CD1 . TYR G 1 130 ? 60.023 -44.490 35.655 1.00 114.38 ? 130 TYR G CD1 1 +ATOM 12426 C CD2 . TYR G 1 130 ? 61.651 -43.323 36.982 1.00 119.90 ? 130 TYR G CD2 1 +ATOM 12427 C CE1 . TYR G 1 130 ? 60.159 -45.600 36.470 1.00 147.35 ? 130 TYR G CE1 1 +ATOM 12428 C CE2 . TYR G 1 130 ? 61.820 -44.430 37.778 1.00 122.13 ? 130 TYR G CE2 1 +ATOM 12429 C CZ . TYR G 1 130 ? 61.081 -45.567 37.521 1.00 156.70 ? 130 TYR G CZ 1 +ATOM 12430 O OH . TYR G 1 130 ? 61.226 -46.648 38.360 1.00 196.69 ? 130 TYR G OH 1 +ATOM 12431 N N . GLU G 1 131 ? 61.092 -44.212 32.181 1.00 115.76 ? 131 GLU G N 1 +ATOM 12432 C CA . GLU G 1 131 ? 60.520 -45.433 31.616 1.00 139.60 ? 131 GLU G CA 1 +ATOM 12433 C C . GLU G 1 131 ? 60.823 -46.586 32.562 1.00 122.56 ? 131 GLU G C 1 +ATOM 12434 O O . GLU G 1 131 ? 61.846 -46.574 33.231 1.00 118.49 ? 131 GLU G O 1 +ATOM 12435 C CB . GLU G 1 131 ? 61.090 -45.682 30.219 1.00 138.56 ? 131 GLU G CB 1 +ATOM 12436 C CG . GLU G 1 131 ? 60.419 -46.798 29.425 1.00 115.26 ? 131 GLU G CG 1 +ATOM 12437 C CD . GLU G 1 131 ? 59.218 -46.340 28.602 1.00 113.97 ? 131 GLU G CD 1 +ATOM 12438 O OE1 . GLU G 1 131 ? 59.179 -45.155 28.176 1.00 83.72 ? 131 GLU G OE1 1 +ATOM 12439 O OE2 . GLU G 1 131 ? 58.311 -47.174 28.382 1.00 127.39 ? 131 GLU G OE2 1 +ATOM 12440 N N . SER G 1 132 ? 59.913 -47.552 32.642 1.00 114.64 ? 132 SER G N 1 +ATOM 12441 C CA . SER G 1 132 ? 60.006 -48.595 33.660 1.00 108.17 ? 132 SER G CA 1 +ATOM 12442 C C . SER G 1 132 ? 60.117 -49.998 33.038 1.00 139.78 ? 132 SER G C 1 +ATOM 12443 O O . SER G 1 132 ? 59.465 -50.299 32.038 1.00 161.03 ? 132 SER G O 1 +ATOM 12444 C CB . SER G 1 132 ? 58.808 -48.536 34.605 1.00 92.50 ? 132 SER G CB 1 +ATOM 12445 O OG . SER G 1 132 ? 57.984 -49.694 34.460 1.00 84.81 ? 132 SER G OG 1 +ATOM 12446 N N . ASN G 1 133 ? 60.917 -50.859 33.666 1.00 144.96 ? 133 ASN G N 1 +ATOM 12447 C CA . ASN G 1 133 ? 61.318 -52.146 33.068 1.00 118.51 ? 133 ASN G CA 1 +ATOM 12448 C C . ASN G 1 133 ? 61.737 -51.980 31.615 1.00 116.35 ? 133 ASN G C 1 +ATOM 12449 O O . ASN G 1 133 ? 61.191 -52.618 30.721 1.00 95.65 ? 133 ASN G O 1 +ATOM 12450 C CB . ASN G 1 133 ? 60.202 -53.171 33.166 1.00 93.40 ? 133 ASN G CB 1 +ATOM 12451 C CG . ASN G 1 133 ? 59.801 -53.445 34.592 1.00 114.41 ? 133 ASN G CG 1 +ATOM 12452 O OD1 . ASN G 1 133 ? 60.611 -53.326 35.533 1.00 137.21 ? 133 ASN G OD1 1 +ATOM 12453 N ND2 . ASN G 1 133 ? 58.537 -53.773 34.778 1.00 128.17 ? 133 ASN G ND2 1 +ATOM 12454 N N . VAL G 1 134 ? 62.730 -51.121 31.404 1.00 122.27 ? 134 VAL G N 1 +ATOM 12455 C CA . VAL G 1 134 ? 63.276 -50.877 30.084 1.00 124.78 ? 134 VAL G CA 1 +ATOM 12456 C C . VAL G 1 134 ? 63.993 -52.151 29.642 1.00 132.94 ? 134 VAL G C 1 +ATOM 12457 O O . VAL G 1 134 ? 63.952 -52.523 28.465 1.00 141.39 ? 134 VAL G O 1 +ATOM 12458 C CB . VAL G 1 134 ? 64.245 -49.673 30.097 1.00 144.46 ? 134 VAL G CB 1 +ATOM 12459 C CG1 . VAL G 1 134 ? 64.752 -49.362 28.692 1.00 143.71 ? 134 VAL G CG1 1 +ATOM 12460 C CG2 . VAL G 1 134 ? 63.559 -48.441 30.686 1.00 152.74 ? 134 VAL G CG2 1 +ATOM 12461 N N . LYS G 1 135 ? 64.599 -52.842 30.605 1.00 136.14 ? 135 LYS G N 1 +ATOM 12462 C CA . LYS G 1 135 ? 65.011 -54.228 30.401 1.00 140.76 ? 135 LYS G CA 1 +ATOM 12463 C C . LYS G 1 135 ? 64.661 -55.088 31.602 1.00 152.45 ? 135 LYS G C 1 +ATOM 12464 O O . LYS G 1 135 ? 64.498 -54.592 32.732 1.00 151.92 ? 135 LYS G O 1 +ATOM 12465 C CB . LYS G 1 135 ? 66.514 -54.305 30.145 1.00 171.28 ? 135 LYS G CB 1 +ATOM 12466 C CG . LYS G 1 135 ? 66.950 -53.584 28.882 1.00 192.08 ? 135 LYS G CG 1 +ATOM 12467 C CD . LYS G 1 135 ? 68.459 -53.605 28.753 1.00 235.33 ? 135 LYS G CD 1 +ATOM 12468 C CE . LYS G 1 135 ? 68.920 -52.879 27.505 1.00 238.03 ? 135 LYS G CE 1 +ATOM 12469 N NZ . LYS G 1 135 ? 70.287 -53.322 27.127 1.00 292.56 ? 135 LYS G NZ 1 +ATOM 12470 N N . SER G 1 136 ? 64.603 -56.395 31.366 1.00 180.39 ? 136 SER G N 1 +ATOM 12471 C CA . SER G 1 136 ? 64.320 -57.354 32.431 1.00 206.86 ? 136 SER G CA 1 +ATOM 12472 C C . SER G 1 136 ? 64.710 -58.775 32.035 1.00 178.05 ? 136 SER G C 1 +ATOM 12473 O O . SER G 1 136 ? 64.793 -59.091 30.851 1.00 167.88 ? 136 SER G O 1 +ATOM 12474 C CB . SER G 1 136 ? 62.843 -57.295 32.823 1.00 219.21 ? 136 SER G CB 1 +ATOM 12475 O OG . SER G 1 136 ? 62.231 -58.572 32.734 1.00 221.99 ? 136 SER G OG 1 +ATOM 12476 N N . GLY G 1 137 ? 64.960 -59.617 33.037 1.00 132.11 ? 137 GLY G N 1 +ATOM 12477 C CA . GLY G 1 137 ? 65.296 -61.010 32.782 1.00 145.80 ? 137 GLY G CA 1 +ATOM 12478 C C . GLY G 1 137 ? 65.278 -61.885 34.019 1.00 150.68 ? 137 GLY G C 1 +ATOM 12479 O O . GLY G 1 137 ? 65.009 -61.416 35.122 1.00 123.66 ? 137 GLY G O 1 +ATOM 12480 N N . GLY G 1 138 ? 65.500 -63.182 33.820 1.00 177.19 ? 138 GLY G N 1 +ATOM 12481 C CA . GLY G 1 138 ? 65.480 -64.136 34.921 1.00 189.53 ? 138 GLY G CA 1 +ATOM 12482 C C . GLY G 1 138 ? 66.086 -65.474 34.556 1.00 197.40 ? 138 GLY G C 1 +ATOM 12483 O O . GLY G 1 138 ? 65.960 -65.933 33.417 1.00 179.01 ? 138 GLY G O 1 +ATOM 12484 N N . VAL G 1 139 ? 66.747 -66.097 35.530 1.00 188.38 ? 139 VAL G N 1 +ATOM 12485 C CA . VAL G 1 139 ? 67.323 -67.429 35.353 1.00 157.64 ? 139 VAL G CA 1 +ATOM 12486 C C . VAL G 1 139 ? 67.094 -68.269 36.605 1.00 118.81 ? 139 VAL G C 1 +ATOM 12487 O O . VAL G 1 139 ? 67.454 -67.865 37.708 1.00 93.17 ? 139 VAL G O 1 +ATOM 12488 C CB . VAL G 1 139 ? 68.838 -67.366 35.072 1.00 147.33 ? 139 VAL G CB 1 +ATOM 12489 C CG1 . VAL G 1 139 ? 69.410 -68.767 35.023 1.00 157.45 ? 139 VAL G CG1 1 +ATOM 12490 C CG2 . VAL G 1 139 ? 69.124 -66.627 33.769 1.00 139.15 ? 139 VAL G CG2 1 +ATOM 12491 N N . GLY G 1 140 ? 66.495 -69.442 36.417 1.00 123.19 ? 140 GLY G N 1 +ATOM 12492 C CA . GLY G 1 140 ? 66.188 -70.336 37.527 1.00 146.32 ? 140 GLY G CA 1 +ATOM 12493 C C . GLY G 1 140 ? 66.178 -71.811 37.167 1.00 162.44 ? 140 GLY G C 1 +ATOM 12494 O O . GLY G 1 140 ? 65.801 -72.194 36.058 1.00 182.29 ? 140 GLY G O 1 +ATOM 12495 N N . ALA G 1 141 ? 66.581 -72.645 38.121 1.00 149.61 ? 141 ALA G N 1 +ATOM 12496 C CA . ALA G 1 141 ? 66.588 -74.089 37.915 1.00 116.85 ? 141 ALA G CA 1 +ATOM 12497 C C . ALA G 1 141 ? 66.245 -74.837 39.195 1.00 119.82 ? 141 ALA G C 1 +ATOM 12498 O O . ALA G 1 141 ? 66.634 -74.445 40.300 1.00 130.43 ? 141 ALA G O 1 +ATOM 12499 C CB . ALA G 1 141 ? 67.933 -74.542 37.379 1.00 106.77 ? 141 ALA G CB 1 +ATOM 12500 N N . ARG G 1 142 ? 65.473 -75.901 39.045 1.00 131.37 ? 142 ARG G N 1 +ATOM 12501 C CA . ARG G 1 142 ? 65.236 -76.809 40.152 1.00 139.89 ? 142 ARG G CA 1 +ATOM 12502 C C . ARG G 1 142 ? 65.565 -78.217 39.701 1.00 166.24 ? 142 ARG G C 1 +ATOM 12503 O O . ARG G 1 142 ? 65.362 -78.570 38.537 1.00 177.96 ? 142 ARG G O 1 +ATOM 12504 C CB . ARG G 1 142 ? 63.793 -76.724 40.664 1.00 126.90 ? 142 ARG G CB 1 +ATOM 12505 C CG . ARG G 1 142 ? 63.546 -77.601 41.884 1.00 123.85 ? 142 ARG G CG 1 +ATOM 12506 C CD . ARG G 1 142 ? 62.693 -76.913 42.928 1.00 147.12 ? 142 ARG G CD 1 +ATOM 12507 N NE . ARG G 1 142 ? 61.277 -77.007 42.591 1.00 162.81 ? 142 ARG G NE 1 +ATOM 12508 C CZ . ARG G 1 142 ? 60.341 -76.154 42.994 1.00 173.50 ? 142 ARG G CZ 1 +ATOM 12509 N NH1 . ARG G 1 142 ? 60.651 -75.129 43.780 1.00 200.62 ? 142 ARG G NH1 1 +ATOM 12510 N NH2 . ARG G 1 142 ? 59.074 -76.340 42.633 1.00 149.45 ? 142 ARG G NH2 1 +ATOM 12511 N N . TYR G 1 143 ? 66.142 -78.989 40.615 1.00 181.34 ? 143 TYR G N 1 +ATOM 12512 C CA . TYR G 1 143 ? 66.664 -80.307 40.293 1.00 162.99 ? 143 TYR G CA 1 +ATOM 12513 C C . TYR G 1 143 ? 66.116 -81.263 41.343 1.00 114.92 ? 143 TYR G C 1 +ATOM 12514 O O . TYR G 1 143 ? 66.821 -82.179 41.774 1.00 87.18 ? 143 TYR G O 1 +ATOM 12515 C CB . TYR G 1 143 ? 68.205 -80.274 40.303 1.00 154.99 ? 143 TYR G CB 1 +ATOM 12516 C CG . TYR G 1 143 ? 68.888 -81.527 39.838 1.00 164.20 ? 143 TYR G CG 1 +ATOM 12517 C CD1 . TYR G 1 143 ? 68.798 -81.920 38.518 1.00 175.95 ? 143 TYR G CD1 1 +ATOM 12518 C CD2 . TYR G 1 143 ? 69.669 -82.293 40.705 1.00 160.25 ? 143 TYR G CD2 1 +ATOM 12519 C CE1 . TYR G 1 143 ? 69.454 -83.054 38.060 1.00 170.10 ? 143 TYR G CE1 1 +ATOM 12520 C CE2 . TYR G 1 143 ? 70.282 -83.460 40.271 1.00 167.75 ? 143 TYR G CE2 1 +ATOM 12521 C CZ . TYR G 1 143 ? 70.173 -83.833 38.947 1.00 164.31 ? 143 TYR G CZ 1 +ATOM 12522 O OH . TYR G 1 143 ? 70.799 -84.973 38.510 1.00 165.91 ? 143 TYR G OH 1 +ATOM 12523 N N . GLY G 1 145 ? 64.913 -81.715 43.727 1.00 142.39 ? 145 GLY G N 1 +ATOM 12524 C CA . GLY G 1 145 ? 64.571 -81.278 45.069 1.00 166.08 ? 145 GLY G CA 1 +ATOM 12525 C C . GLY G 1 145 ? 65.117 -79.913 45.470 1.00 199.64 ? 145 GLY G C 1 +ATOM 12526 O O . GLY G 1 145 ? 64.518 -79.235 46.292 1.00 168.43 ? 145 GLY G O 1 +ATOM 12527 N N . ILE G 1 146 ? 66.198 -79.469 44.833 1.00 242.13 ? 146 ILE G N 1 +ATOM 12528 C CA . ILE G 1 146 ? 66.887 -78.227 45.208 1.00 230.13 ? 146 ILE G CA 1 +ATOM 12529 C C . ILE G 1 146 ? 66.747 -77.200 44.084 1.00 206.10 ? 146 ILE G C 1 +ATOM 12530 O O . ILE G 1 146 ? 66.898 -77.554 42.902 1.00 276.60 ? 146 ILE G O 1 +ATOM 12531 C CB . ILE G 1 146 ? 68.387 -78.484 45.502 1.00 242.72 ? 146 ILE G CB 1 +ATOM 12532 C CG1 . ILE G 1 146 ? 68.566 -79.814 46.251 1.00 243.68 ? 146 ILE G CG1 1 +ATOM 12533 C CG2 . ILE G 1 146 ? 68.985 -77.338 46.308 1.00 228.42 ? 146 ILE G CG2 1 +ATOM 12534 C CD1 . ILE G 1 146 ? 68.922 -80.987 45.361 1.00 217.59 ? 146 ILE G CD1 1 +ATOM 12535 N N . GLY G 1 147 ? 66.468 -75.939 44.425 1.00 122.63 ? 147 GLY G N 1 +ATOM 12536 C CA . GLY G 1 147 ? 66.283 -74.930 43.378 1.00 121.80 ? 147 GLY G CA 1 +ATOM 12537 C C . GLY G 1 147 ? 66.683 -73.511 43.728 1.00 121.91 ? 147 GLY G C 1 +ATOM 12538 O O . GLY G 1 147 ? 66.719 -73.130 44.886 1.00 82.93 ? 147 GLY G O 1 +ATOM 12539 N N . ALA G 1 148 ? 67.030 -72.733 42.705 1.00 153.41 ? 148 ALA G N 1 +ATOM 12540 C CA . ALA G 1 148 ? 67.333 -71.315 42.883 1.00 143.80 ? 148 ALA G CA 1 +ATOM 12541 C C . ALA G 1 148 ? 66.966 -70.538 41.635 1.00 152.19 ? 148 ALA G C 1 +ATOM 12542 O O . ALA G 1 148 ? 66.653 -71.118 40.578 1.00 121.88 ? 148 ALA G O 1 +ATOM 12543 C CB . ALA G 1 148 ? 68.803 -71.105 43.205 1.00 133.73 ? 148 ALA G CB 1 +ATOM 12544 N N . ASP G 1 149 ? 66.929 -69.219 41.783 1.00 167.58 ? 149 ASP G N 1 +ATOM 12545 C CA . ASP G 1 149 ? 66.587 -68.351 40.665 1.00 174.40 ? 149 ASP G CA 1 +ATOM 12546 C C . ASP G 1 149 ? 66.942 -66.911 40.993 1.00 127.60 ? 149 ASP G C 1 +ATOM 12547 O O . ASP G 1 149 ? 66.838 -66.490 42.139 1.00 73.36 ? 149 ASP G O 1 +ATOM 12548 C CB . ASP G 1 149 ? 65.091 -68.483 40.279 1.00 204.21 ? 149 ASP G CB 1 +ATOM 12549 C CG . ASP G 1 149 ? 64.180 -67.682 41.173 1.00 190.85 ? 149 ASP G CG 1 +ATOM 12550 O OD1 . ASP G 1 149 ? 63.943 -68.127 42.306 1.00 239.17 ? 149 ASP G OD1 1 +ATOM 12551 O OD2 . ASP G 1 149 ? 63.677 -66.645 40.720 1.00 124.93 ? 149 ASP G OD2 1 +ATOM 12552 N N . THR G 1 150 ? 67.323 -66.156 39.970 1.00 138.05 ? 150 THR G N 1 +ATOM 12553 C CA . THR G 1 150 ? 67.350 -64.707 40.083 1.00 149.46 ? 150 THR G CA 1 +ATOM 12554 C C . THR G 1 150 ? 66.474 -64.071 39.014 1.00 182.09 ? 150 THR G C 1 +ATOM 12555 O O . THR G 1 150 ? 66.192 -64.666 37.969 1.00 191.71 ? 150 THR G O 1 +ATOM 12556 C CB . THR G 1 150 ? 68.769 -64.136 39.960 1.00 127.59 ? 150 THR G CB 1 +ATOM 12557 O OG1 . THR G 1 150 ? 69.316 -64.496 38.687 1.00 120.87 ? 150 THR G OG1 1 +ATOM 12558 C CG2 . THR G 1 150 ? 69.649 -64.653 41.076 1.00 118.47 ? 150 THR G CG2 1 +ATOM 12559 N N . GLN G 1 151 ? 66.000 -62.870 39.317 1.00 193.77 ? 151 GLN G N 1 +ATOM 12560 C CA . GLN G 1 151 ? 65.243 -62.069 38.376 1.00 186.97 ? 151 GLN G CA 1 +ATOM 12561 C C . GLN G 1 151 ? 65.706 -60.631 38.484 1.00 156.35 ? 151 GLN G C 1 +ATOM 12562 O O . GLN G 1 151 ? 66.052 -60.191 39.562 1.00 120.92 ? 151 GLN G O 1 +ATOM 12563 C CB . GLN G 1 151 ? 63.756 -62.167 38.707 1.00 169.33 ? 151 GLN G CB 1 +ATOM 12564 C CG . GLN G 1 151 ? 63.161 -63.510 38.327 1.00 159.84 ? 151 GLN G CG 1 +ATOM 12565 C CD . GLN G 1 151 ? 61.875 -63.803 39.051 1.00 169.81 ? 151 GLN G CD 1 +ATOM 12566 O OE1 . GLN G 1 151 ? 61.067 -62.900 39.267 1.00 187.09 ? 151 GLN G OE1 1 +ATOM 12567 N NE2 . GLN G 1 151 ? 61.703 -65.049 39.489 1.00 172.17 ? 151 GLN G NE2 1 +ATOM 12568 N N . TYR G 1 152 ? 65.770 -59.920 37.363 1.00 135.56 ? 152 TYR G N 1 +ATOM 12569 C CA . TYR G 1 152 ? 66.197 -58.536 37.403 1.00 106.53 ? 152 TYR G CA 1 +ATOM 12570 C C . TYR G 1 152 ? 65.368 -57.659 36.499 1.00 139.47 ? 152 TYR G C 1 +ATOM 12571 O O . TYR G 1 152 ? 64.878 -58.101 35.454 1.00 159.19 ? 152 TYR G O 1 +ATOM 12572 C CB . TYR G 1 152 ? 67.655 -58.418 37.030 1.00 90.73 ? 152 TYR G CB 1 +ATOM 12573 C CG . TYR G 1 152 ? 67.926 -57.869 35.633 1.00 88.52 ? 152 TYR G CG 1 +ATOM 12574 C CD1 . TYR G 1 152 ? 67.610 -58.584 34.486 1.00 69.43 ? 152 TYR G CD1 1 +ATOM 12575 C CD2 . TYR G 1 152 ? 68.649 -56.691 35.473 1.00 98.85 ? 152 TYR G CD2 1 +ATOM 12576 C CE1 . TYR G 1 152 ? 67.955 -58.110 33.228 1.00 71.79 ? 152 TYR G CE1 1 +ATOM 12577 C CE2 . TYR G 1 152 ? 69.062 -56.244 34.209 1.00 77.44 ? 152 TYR G CE2 1 +ATOM 12578 C CZ . TYR G 1 152 ? 68.719 -56.949 33.093 1.00 67.71 ? 152 TYR G CZ 1 +ATOM 12579 O OH . TYR G 1 152 ? 69.139 -56.510 31.843 1.00 67.37 ? 152 TYR G OH 1 +ATOM 12580 N N . GLN G 1 153 ? 65.192 -56.411 36.915 1.00 174.28 ? 153 GLN G N 1 +ATOM 12581 C CA . GLN G 1 153 ? 64.577 -55.405 36.061 1.00 178.07 ? 153 GLN G CA 1 +ATOM 12582 C C . GLN G 1 153 ? 65.352 -54.100 36.155 1.00 146.43 ? 153 GLN G C 1 +ATOM 12583 O O . GLN G 1 153 ? 66.027 -53.844 37.155 1.00 135.52 ? 153 GLN G O 1 +ATOM 12584 C CB . GLN G 1 153 ? 63.118 -55.189 36.470 1.00 195.27 ? 153 GLN G CB 1 +ATOM 12585 C CG . GLN G 1 153 ? 62.194 -56.398 36.257 1.00 212.02 ? 153 GLN G CG 1 +ATOM 12586 C CD . GLN G 1 153 ? 60.778 -56.134 36.799 1.00 225.30 ? 153 GLN G CD 1 +ATOM 12587 O OE1 . GLN G 1 153 ? 60.574 -55.251 37.644 1.00 257.98 ? 153 GLN G OE1 1 +ATOM 12588 N NE2 . GLN G 1 153 ? 59.800 -56.891 36.313 1.00 214.94 ? 153 GLN G NE2 1 +ATOM 12589 N N . LEU G 1 154 ? 65.285 -53.297 35.101 1.00 118.35 ? 154 LEU G N 1 +ATOM 12590 C CA . LEU G 1 154 ? 65.881 -51.981 35.166 1.00 121.05 ? 154 LEU G CA 1 +ATOM 12591 C C . LEU G 1 154 ? 65.077 -50.922 34.420 1.00 146.48 ? 154 LEU G C 1 +ATOM 12592 O O . LEU G 1 154 ? 64.514 -51.169 33.337 1.00 166.49 ? 154 LEU G O 1 +ATOM 12593 C CB . LEU G 1 154 ? 67.326 -52.005 34.661 1.00 117.30 ? 154 LEU G CB 1 +ATOM 12594 C CG . LEU G 1 154 ? 67.510 -52.185 33.151 1.00 126.46 ? 154 LEU G CG 1 +ATOM 12595 C CD1 . LEU G 1 154 ? 67.665 -50.852 32.430 1.00 110.81 ? 154 LEU G CD1 1 +ATOM 12596 C CD2 . LEU G 1 154 ? 68.711 -53.080 32.894 1.00 159.55 ? 154 LEU G CD2 1 +ATOM 12597 N N . ASP G 1 155 ? 65.143 -49.707 34.971 1.00 158.62 ? 155 ASP G N 1 +ATOM 12598 C CA . ASP G 1 155 ? 64.323 -48.564 34.562 1.00 121.04 ? 155 ASP G CA 1 +ATOM 12599 C C . ASP G 1 155 ? 65.249 -47.437 34.079 1.00 95.14 ? 155 ASP G C 1 +ATOM 12600 O O . ASP G 1 155 ? 66.419 -47.395 34.467 1.00 125.44 ? 155 ASP G O 1 +ATOM 12601 C CB . ASP G 1 155 ? 63.464 -48.101 35.761 1.00 126.23 ? 155 ASP G CB 1 +ATOM 12602 C CG . ASP G 1 155 ? 62.771 -49.261 36.481 1.00 136.21 ? 155 ASP G CG 1 +ATOM 12603 O OD1 . ASP G 1 155 ? 63.436 -49.971 37.262 1.00 121.60 ? 155 ASP G OD1 1 +ATOM 12604 O OD2 . ASP G 1 155 ? 61.580 -49.505 36.198 1.00 172.73 ? 155 ASP G OD2 1 +ATOM 12605 N N . GLN G 1 156 ? 64.721 -46.497 33.307 1.00 72.77 ? 156 GLN G N 1 +ATOM 12606 C CA . GLN G 1 156 ? 65.495 -45.312 32.910 1.00 80.34 ? 156 GLN G CA 1 +ATOM 12607 C C . GLN G 1 156 ? 64.977 -43.976 33.534 1.00 99.39 ? 156 GLN G C 1 +ATOM 12608 O O . GLN G 1 156 ? 63.819 -43.860 33.947 1.00 128.18 ? 156 GLN G O 1 +ATOM 12609 C CB . GLN G 1 156 ? 65.493 -45.206 31.409 1.00 66.25 ? 156 GLN G CB 1 +ATOM 12610 C CG . GLN G 1 156 ? 66.480 -44.212 30.843 1.00 70.79 ? 156 GLN G CG 1 +ATOM 12611 C CD . GLN G 1 156 ? 66.769 -44.468 29.374 1.00 97.83 ? 156 GLN G CD 1 +ATOM 12612 O OE1 . GLN G 1 156 ? 66.152 -45.347 28.744 1.00 123.95 ? 156 GLN G OE1 1 +ATOM 12613 N NE2 . GLN G 1 156 ? 67.729 -43.728 28.817 1.00 111.20 ? 156 GLN G NE2 1 +ATOM 12614 N N . ILE G 1 157 ? 65.857 -42.982 33.623 1.00 75.97 ? 157 ILE G N 1 +ATOM 12615 C CA . ILE G 1 157 ? 65.503 -41.667 34.110 1.00 64.53 ? 157 ILE G CA 1 +ATOM 12616 C C . ILE G 1 157 ? 66.430 -40.631 33.456 1.00 55.36 ? 157 ILE G C 1 +ATOM 12617 O O . ILE G 1 157 ? 67.592 -40.889 33.230 1.00 44.96 ? 157 ILE G O 1 +ATOM 12618 C CB . ILE G 1 157 ? 65.615 -41.593 35.647 1.00 73.72 ? 157 ILE G CB 1 +ATOM 12619 C CG1 . ILE G 1 157 ? 64.719 -40.466 36.213 1.00 102.86 ? 157 ILE G CG1 1 +ATOM 12620 C CG2 . ILE G 1 157 ? 67.051 -41.348 36.067 1.00 69.01 ? 157 ILE G CG2 1 +ATOM 12621 C CD1 . ILE G 1 157 ? 64.617 -40.429 37.736 1.00 79.81 ? 157 ILE G CD1 1 +ATOM 12622 N N . ALA G 1 158 ? 65.887 -39.488 33.071 1.00 73.90 ? 158 ALA G N 1 +ATOM 12623 C CA . ALA G 1 158 ? 66.672 -38.519 32.325 1.00 100.85 ? 158 ALA G CA 1 +ATOM 12624 C C . ALA G 1 158 ? 66.389 -37.149 32.845 1.00 78.49 ? 158 ALA G C 1 +ATOM 12625 O O . ALA G 1 158 ? 65.286 -36.873 33.333 1.00 127.80 ? 158 ALA G O 1 +ATOM 12626 C CB . ALA G 1 158 ? 66.398 -38.590 30.805 1.00 141.92 ? 158 ALA G CB 1 +ATOM 12627 N N . VAL G 1 159 ? 67.354 -36.266 32.657 1.00 61.35 ? 159 VAL G N 1 +ATOM 12628 C CA . VAL G 1 159 ? 67.277 -34.953 33.244 1.00 76.72 ? 159 VAL G CA 1 +ATOM 12629 C C . VAL G 1 159 ? 67.870 -33.929 32.291 1.00 66.47 ? 159 VAL G C 1 +ATOM 12630 O O . VAL G 1 159 ? 68.966 -34.071 31.808 1.00 58.21 ? 159 VAL G O 1 +ATOM 12631 C CB . VAL G 1 159 ? 67.993 -34.893 34.628 1.00 94.77 ? 159 VAL G CB 1 +ATOM 12632 C CG1 . VAL G 1 159 ? 68.354 -33.459 35.005 1.00 94.85 ? 159 VAL G CG1 1 +ATOM 12633 C CG2 . VAL G 1 159 ? 67.133 -35.520 35.736 1.00 89.36 ? 159 VAL G CG2 1 +ATOM 12634 N N . ASN G 1 160 ? 67.112 -32.868 32.066 1.00 90.10 ? 160 ASN G N 1 +ATOM 12635 C CA . ASN G 1 160 ? 67.595 -31.689 31.374 1.00 71.89 ? 160 ASN G CA 1 +ATOM 12636 C C . ASN G 1 160 ? 68.015 -30.681 32.440 1.00 58.70 ? 160 ASN G C 1 +ATOM 12637 O O . ASN G 1 160 ? 67.240 -30.350 33.346 1.00 47.18 ? 160 ASN G O 1 +ATOM 12638 C CB . ASN G 1 160 ? 66.476 -31.123 30.468 1.00 66.68 ? 160 ASN G CB 1 +ATOM 12639 C CG . ASN G 1 160 ? 66.885 -29.843 29.742 1.00 72.05 ? 160 ASN G CG 1 +ATOM 12640 O OD1 . ASN G 1 160 ? 67.350 -28.883 30.341 1.00 113.06 ? 160 ASN G OD1 1 +ATOM 12641 N ND2 . ASN G 1 160 ? 66.582 -29.776 28.466 1.00 95.33 ? 160 ASN G ND2 1 +ATOM 12642 N N . LEU G 1 161 ? 69.217 -30.165 32.308 1.00 60.16 ? 161 LEU G N 1 +ATOM 12643 C CA . LEU G 1 161 ? 69.560 -28.873 32.924 1.00 70.19 ? 161 LEU G CA 1 +ATOM 12644 C C . LEU G 1 161 ? 70.027 -27.832 31.876 1.00 61.58 ? 161 LEU G C 1 +ATOM 12645 O O . LEU G 1 161 ? 70.591 -28.198 30.847 1.00 69.47 ? 161 LEU G O 1 +ATOM 12646 C CB . LEU G 1 161 ? 70.670 -29.089 33.927 1.00 69.97 ? 161 LEU G CB 1 +ATOM 12647 C CG . LEU G 1 161 ? 70.310 -29.995 35.097 1.00 76.21 ? 161 LEU G CG 1 +ATOM 12648 C CD1 . LEU G 1 161 ? 71.556 -30.284 35.899 1.00 97.32 ? 161 LEU G CD1 1 +ATOM 12649 C CD2 . LEU G 1 161 ? 69.269 -29.303 35.945 1.00 91.78 ? 161 LEU G CD2 1 +ATOM 12650 N N . ARG G 1 162 ? 69.784 -26.556 32.125 1.00 42.92 ? 162 ARG G N 1 +ATOM 12651 C CA . ARG G 1 162 ? 70.172 -25.566 31.160 1.00 56.38 ? 162 ARG G CA 1 +ATOM 12652 C C . ARG G 1 162 ? 70.430 -24.197 31.762 1.00 67.31 ? 162 ARG G C 1 +ATOM 12653 O O . ARG G 1 162 ? 69.615 -23.668 32.524 1.00 89.78 ? 162 ARG G O 1 +ATOM 12654 C CB . ARG G 1 162 ? 69.163 -25.482 30.002 1.00 84.08 ? 162 ARG G CB 1 +ATOM 12655 C CG . ARG G 1 162 ? 67.735 -25.036 30.333 1.00 114.53 ? 162 ARG G CG 1 +ATOM 12656 C CD . ARG G 1 162 ? 66.990 -24.613 29.061 1.00 100.39 ? 162 ARG G CD 1 +ATOM 12657 N NE . ARG G 1 162 ? 65.693 -23.996 29.322 1.00 91.29 ? 162 ARG G NE 1 +ATOM 12658 C CZ . ARG G 1 162 ? 64.575 -24.671 29.582 1.00 125.92 ? 162 ARG G CZ 1 +ATOM 12659 N NH1 . ARG G 1 162 ? 64.580 -26.006 29.667 1.00 155.22 ? 162 ARG G NH1 1 +ATOM 12660 N NH2 . ARG G 1 162 ? 63.441 -24.011 29.784 1.00 122.78 ? 162 ARG G NH2 1 +ATOM 12661 N N . VAL G 1 163 ? 71.556 -23.606 31.350 1.00 77.06 ? 163 VAL G N 1 +ATOM 12662 C CA . VAL G 1 163 ? 71.986 -22.270 31.797 1.00 83.72 ? 163 VAL G CA 1 +ATOM 12663 C C . VAL G 1 163 ? 71.413 -21.198 30.920 1.00 85.92 ? 163 VAL G C 1 +ATOM 12664 O O . VAL G 1 163 ? 71.617 -21.210 29.710 1.00 115.42 ? 163 VAL G O 1 +ATOM 12665 C CB . VAL G 1 163 ? 73.499 -22.069 31.697 1.00 75.23 ? 163 VAL G CB 1 +ATOM 12666 C CG1 . VAL G 1 163 ? 73.866 -20.653 32.136 1.00 55.19 ? 163 VAL G CG1 1 +ATOM 12667 C CG2 . VAL G 1 163 ? 74.209 -23.149 32.518 1.00 95.69 ? 163 VAL G CG2 1 +ATOM 12668 N N . VAL G 1 164 ? 70.685 -20.285 31.551 1.00 73.19 ? 164 VAL G N 1 +ATOM 12669 C CA . VAL G 1 164 ? 70.043 -19.205 30.858 1.00 83.17 ? 164 VAL G CA 1 +ATOM 12670 C C . VAL G 1 164 ? 70.734 -17.943 31.310 1.00 73.21 ? 164 VAL G C 1 +ATOM 12671 O O . VAL G 1 164 ? 70.870 -17.710 32.498 1.00 42.36 ? 164 VAL G O 1 +ATOM 12672 C CB . VAL G 1 164 ? 68.535 -19.117 31.185 1.00 129.82 ? 164 VAL G CB 1 +ATOM 12673 C CG1 . VAL G 1 164 ? 67.896 -17.921 30.482 1.00 143.21 ? 164 VAL G CG1 1 +ATOM 12674 C CG2 . VAL G 1 164 ? 67.826 -20.399 30.766 1.00 153.24 ? 164 VAL G CG2 1 +ATOM 12675 N N . ASN G 1 165 ? 71.020 -17.080 30.339 1.00 75.67 ? 165 ASN G N 1 +ATOM 12676 C CA . ASN G 1 165 ? 71.558 -15.771 30.621 1.00 68.16 ? 165 ASN G CA 1 +ATOM 12677 C C . ASN G 1 165 ? 70.482 -14.754 30.959 1.00 90.27 ? 165 ASN G C 1 +ATOM 12678 O O . ASN G 1 165 ? 69.611 -14.447 30.123 1.00 129.51 ? 165 ASN G O 1 +ATOM 12679 C CB . ASN G 1 165 ? 72.334 -15.251 29.440 1.00 73.72 ? 165 ASN G CB 1 +ATOM 12680 C CG . ASN G 1 165 ? 73.069 -13.986 29.776 1.00 109.40 ? 165 ASN G CG 1 +ATOM 12681 O OD1 . ASN G 1 165 ? 73.262 -13.669 30.958 1.00 139.75 ? 165 ASN G OD1 1 +ATOM 12682 N ND2 . ASN G 1 165 ? 73.617 -13.340 28.758 1.00 152.08 ? 165 ASN G ND2 1 +ATOM 12683 N N . VAL G 1 166 ? 70.536 -14.237 32.184 1.00 97.44 ? 166 VAL G N 1 +ATOM 12684 C CA . VAL G 1 166 ? 69.539 -13.301 32.683 1.00 93.80 ? 166 VAL G CA 1 +ATOM 12685 C C . VAL G 1 166 ? 69.529 -12.075 31.806 1.00 90.71 ? 166 VAL G C 1 +ATOM 12686 O O . VAL G 1 166 ? 68.451 -11.530 31.530 1.00 158.01 ? 166 VAL G O 1 +ATOM 12687 C CB . VAL G 1 166 ? 69.828 -12.895 34.141 1.00 119.24 ? 166 VAL G CB 1 +ATOM 12688 C CG1 . VAL G 1 166 ? 69.237 -11.527 34.493 1.00 118.34 ? 166 VAL G CG1 1 +ATOM 12689 C CG2 . VAL G 1 166 ? 69.343 -13.988 35.090 1.00 129.45 ? 166 VAL G CG2 1 +ATOM 12690 N N . SER G 1 167 ? 70.704 -11.672 31.334 1.00 66.18 ? 167 SER G N 1 +ATOM 12691 C CA . SER G 1 167 ? 70.837 -10.404 30.667 1.00 75.45 ? 167 SER G CA 1 +ATOM 12692 C C . SER G 1 167 ? 70.265 -10.421 29.250 1.00 66.57 ? 167 SER G C 1 +ATOM 12693 O O . SER G 1 167 ? 70.023 -9.347 28.658 1.00 63.35 ? 167 SER G O 1 +ATOM 12694 C CB . SER G 1 167 ? 72.302 -9.998 30.633 1.00 103.62 ? 167 SER G CB 1 +ATOM 12695 O OG . SER G 1 167 ? 72.903 -10.171 31.910 1.00 116.37 ? 167 SER G OG 1 +ATOM 12696 N N . THR G 1 168 ? 70.000 -11.613 28.718 1.00 63.77 ? 168 THR G N 1 +ATOM 12697 C CA . THR G 1 168 ? 69.426 -11.730 27.351 1.00 85.20 ? 168 THR G CA 1 +ATOM 12698 C C . THR G 1 168 ? 68.279 -12.752 27.159 1.00 80.19 ? 168 THR G C 1 +ATOM 12699 O O . THR G 1 168 ? 67.355 -12.552 26.353 1.00 82.43 ? 168 THR G O 1 +ATOM 12700 C CB . THR G 1 168 ? 70.511 -12.145 26.380 1.00 90.96 ? 168 THR G CB 1 +ATOM 12701 O OG1 . THR G 1 168 ? 71.165 -13.302 26.906 1.00 63.02 ? 168 THR G OG1 1 +ATOM 12702 C CG2 . THR G 1 168 ? 71.509 -11.003 26.193 1.00 113.53 ? 168 THR G CG2 1 +ATOM 12703 N N . GLY G 1 169 ? 68.302 -13.815 27.942 1.00 62.75 ? 169 GLY G N 1 +ATOM 12704 C CA . GLY G 1 169 ? 67.327 -14.842 27.779 1.00 63.04 ? 169 GLY G CA 1 +ATOM 12705 C C . GLY G 1 169 ? 67.910 -15.916 26.898 1.00 98.01 ? 169 GLY G C 1 +ATOM 12706 O O . GLY G 1 169 ? 67.300 -16.972 26.723 1.00 156.74 ? 169 GLY G O 1 +ATOM 12707 N N . GLU G 1 170 ? 69.034 -15.623 26.236 1.00 106.97 ? 170 GLU G N 1 +ATOM 12708 C CA . GLU G 1 170 ? 69.764 -16.660 25.490 1.00 108.58 ? 170 GLU G CA 1 +ATOM 12709 C C . GLU G 1 170 ? 69.998 -17.801 26.459 1.00 89.60 ? 170 GLU G C 1 +ATOM 12710 O O . GLU G 1 170 ? 70.521 -17.603 27.550 1.00 109.76 ? 170 GLU G O 1 +ATOM 12711 C CB . GLU G 1 170 ? 71.108 -16.136 24.935 1.00 103.69 ? 170 GLU G CB 1 +ATOM 12712 C CG . GLU G 1 170 ? 70.969 -15.282 23.683 1.00 87.93 ? 170 GLU G CG 1 +ATOM 12713 C CD . GLU G 1 170 ? 71.926 -14.108 23.624 1.00 89.43 ? 170 GLU G CD 1 +ATOM 12714 O OE1 . GLU G 1 170 ? 72.623 -13.832 24.639 1.00 111.23 ? 170 GLU G OE1 1 +ATOM 12715 O OE2 . GLU G 1 170 ? 71.982 -13.444 22.560 1.00 85.51 ? 170 GLU G OE2 1 +ATOM 12716 N N . ILE G 1 171 ? 69.644 -19.001 26.058 1.00 69.82 ? 171 ILE G N 1 +ATOM 12717 C CA . ILE G 1 171 ? 70.157 -20.146 26.738 1.00 87.88 ? 171 ILE G CA 1 +ATOM 12718 C C . ILE G 1 171 ? 71.656 -20.292 26.420 1.00 82.32 ? 171 ILE G C 1 +ATOM 12719 O O . ILE G 1 171 ? 72.031 -20.344 25.260 1.00 67.74 ? 171 ILE G O 1 +ATOM 12720 C CB . ILE G 1 171 ? 69.381 -21.395 26.319 1.00 101.89 ? 171 ILE G CB 1 +ATOM 12721 C CG1 . ILE G 1 171 ? 67.963 -21.323 26.877 1.00 92.74 ? 171 ILE G CG1 1 +ATOM 12722 C CG2 . ILE G 1 171 ? 70.102 -22.647 26.808 1.00 113.06 ? 171 ILE G CG2 1 +ATOM 12723 C CD1 . ILE G 1 171 ? 67.019 -22.284 26.209 1.00 95.38 ? 171 ILE G CD1 1 +ATOM 12724 N N . LEU G 1 172 ? 72.498 -20.381 27.452 1.00 101.25 ? 172 LEU G N 1 +ATOM 12725 C CA . LEU G 1 172 ? 73.942 -20.471 27.249 1.00 118.19 ? 172 LEU G CA 1 +ATOM 12726 C C . LEU G 1 172 ? 74.454 -21.921 27.231 1.00 150.45 ? 172 LEU G C 1 +ATOM 12727 O O . LEU G 1 172 ? 75.600 -22.210 26.828 1.00 165.21 ? 172 LEU G O 1 +ATOM 12728 C CB . LEU G 1 172 ? 74.710 -19.683 28.316 1.00 108.12 ? 172 LEU G CB 1 +ATOM 12729 C CG . LEU G 1 172 ? 75.019 -18.199 28.082 1.00 117.43 ? 172 LEU G CG 1 +ATOM 12730 C CD1 . LEU G 1 172 ? 73.977 -17.630 27.144 1.00 96.06 ? 172 LEU G CD1 1 +ATOM 12731 C CD2 . LEU G 1 172 ? 75.228 -17.331 29.321 1.00 134.56 ? 172 LEU G CD2 1 +ATOM 12732 N N . SER G 1 173 ? 73.602 -22.842 27.662 1.00 156.59 ? 173 SER G N 1 +ATOM 12733 C CA . SER G 1 173 ? 73.949 -24.265 27.628 1.00 148.20 ? 173 SER G CA 1 +ATOM 12734 C C . SER G 1 173 ? 72.767 -25.155 27.949 1.00 119.26 ? 173 SER G C 1 +ATOM 12735 O O . SER G 1 173 ? 72.033 -24.892 28.912 1.00 164.41 ? 173 SER G O 1 +ATOM 12736 C CB . SER G 1 173 ? 75.030 -24.551 28.660 1.00 190.05 ? 173 SER G CB 1 +ATOM 12737 O OG . SER G 1 173 ? 75.133 -25.940 28.908 1.00 176.86 ? 173 SER G OG 1 +ATOM 12738 N N . SER G 1 174 ? 72.574 -26.204 27.159 1.00 79.37 ? 174 SER G N 1 +ATOM 12739 C CA . SER G 1 174 ? 71.566 -27.219 27.501 1.00 99.01 ? 174 SER G CA 1 +ATOM 12740 C C . SER G 1 174 ? 72.248 -28.545 27.547 1.00 111.47 ? 174 SER G C 1 +ATOM 12741 O O . SER G 1 174 ? 73.059 -28.858 26.664 1.00 162.70 ? 174 SER G O 1 +ATOM 12742 C CB . SER G 1 174 ? 70.405 -27.267 26.473 1.00 107.68 ? 174 SER G CB 1 +ATOM 12743 O OG . SER G 1 174 ? 69.323 -28.098 26.905 1.00 72.21 ? 174 SER G OG 1 +ATOM 12744 N N . VAL G 1 175 ? 71.902 -29.348 28.545 1.00 103.99 ? 175 VAL G N 1 +ATOM 12745 C CA . VAL G 1 175 ? 72.491 -30.683 28.686 1.00 110.67 ? 175 VAL G CA 1 +ATOM 12746 C C . VAL G 1 175 ? 71.454 -31.721 29.085 1.00 116.23 ? 175 VAL G C 1 +ATOM 12747 O O . VAL G 1 175 ? 70.542 -31.441 29.851 1.00 141.33 ? 175 VAL G O 1 +ATOM 12748 C CB . VAL G 1 175 ? 73.642 -30.711 29.723 1.00 112.24 ? 175 VAL G CB 1 +ATOM 12749 C CG1 . VAL G 1 175 ? 74.787 -29.819 29.271 1.00 125.50 ? 175 VAL G CG1 1 +ATOM 12750 C CG2 . VAL G 1 175 ? 73.168 -30.264 31.088 1.00 113.51 ? 175 VAL G CG2 1 +ATOM 12751 N N . ASN G 1 176 ? 71.638 -32.938 28.589 1.00 129.64 ? 176 ASN G N 1 +ATOM 12752 C CA . ASN G 1 176 ? 70.655 -34.004 28.736 1.00 157.80 ? 176 ASN G CA 1 +ATOM 12753 C C . ASN G 1 176 ? 71.317 -35.281 29.304 1.00 111.57 ? 176 ASN G C 1 +ATOM 12754 O O . ASN G 1 176 ? 71.746 -36.126 28.539 1.00 115.65 ? 176 ASN G O 1 +ATOM 12755 C CB . ASN G 1 176 ? 70.031 -34.292 27.341 1.00 169.52 ? 176 ASN G CB 1 +ATOM 12756 C CG . ASN G 1 176 ? 68.714 -33.548 27.083 1.00 142.38 ? 176 ASN G CG 1 +ATOM 12757 O OD1 . ASN G 1 176 ? 67.912 -33.899 26.167 1.00 88.98 ? 176 ASN G OD1 1 +ATOM 12758 N ND2 . ASN G 1 176 ? 68.413 -32.608 27.966 1.00 170.85 ? 176 ASN G ND2 1 +ATOM 12759 N N . THR G 1 177 ? 71.241 -35.485 30.613 1.00 92.85 ? 177 THR G N 1 +ATOM 12760 C CA . THR G 1 177 ? 71.802 -36.676 31.246 1.00 100.30 ? 177 THR G CA 1 +ATOM 12761 C C . THR G 1 177 ? 70.771 -37.786 31.500 1.00 113.41 ? 177 THR G C 1 +ATOM 12762 O O . THR G 1 177 ? 69.568 -37.531 31.500 1.00 154.91 ? 177 THR G O 1 +ATOM 12763 C CB . THR G 1 177 ? 72.466 -36.321 32.582 1.00 123.04 ? 177 THR G CB 1 +ATOM 12764 O OG1 . THR G 1 177 ? 71.468 -35.986 33.552 1.00 126.17 ? 177 THR G OG1 1 +ATOM 12765 C CG2 . THR G 1 177 ? 73.417 -35.128 32.414 1.00 142.66 ? 177 THR G CG2 1 +ATOM 12766 N N . SER G 1 178 ? 71.255 -39.014 31.707 1.00 135.89 ? 178 SER G N 1 +ATOM 12767 C CA . SER G 1 178 ? 70.397 -40.207 31.848 1.00 126.60 ? 178 SER G CA 1 +ATOM 12768 C C . SER G 1 178 ? 71.034 -41.258 32.754 1.00 98.92 ? 178 SER G C 1 +ATOM 12769 O O . SER G 1 178 ? 72.244 -41.309 32.914 1.00 135.70 ? 178 SER G O 1 +ATOM 12770 C CB . SER G 1 178 ? 70.113 -40.861 30.488 1.00 110.10 ? 178 SER G CB 1 +ATOM 12771 O OG . SER G 1 178 ? 69.550 -42.154 30.662 1.00 99.13 ? 178 SER G OG 1 +ATOM 12772 N N . LYS G 1 179 ? 70.206 -42.084 33.367 1.00 89.39 ? 179 LYS G N 1 +ATOM 12773 C CA . LYS G 1 179 ? 70.676 -42.980 34.407 1.00 101.78 ? 179 LYS G CA 1 +ATOM 12774 C C . LYS G 1 179 ? 69.719 -44.141 34.568 1.00 121.11 ? 179 LYS G C 1 +ATOM 12775 O O . LYS G 1 179 ? 68.489 -43.996 34.443 1.00 209.75 ? 179 LYS G O 1 +ATOM 12776 C CB . LYS G 1 179 ? 70.817 -42.220 35.732 1.00 126.65 ? 179 LYS G CB 1 +ATOM 12777 C CG . LYS G 1 179 ? 71.991 -42.669 36.586 1.00 133.90 ? 179 LYS G CG 1 +ATOM 12778 C CD . LYS G 1 179 ? 71.547 -43.708 37.596 1.00 116.17 ? 179 LYS G CD 1 +ATOM 12779 C CE . LYS G 1 179 ? 72.749 -44.271 38.321 1.00 125.57 ? 179 LYS G CE 1 +ATOM 12780 N NZ . LYS G 1 179 ? 72.388 -45.486 39.087 1.00 127.32 ? 179 LYS G NZ 1 +ATOM 12781 N N . THR G 1 180 ? 70.281 -45.297 34.855 1.00 102.92 ? 180 THR G N 1 +ATOM 12782 C CA . THR G 1 180 ? 69.505 -46.517 34.925 1.00 127.75 ? 180 THR G CA 1 +ATOM 12783 C C . THR G 1 180 ? 69.339 -46.985 36.382 1.00 131.21 ? 180 THR G C 1 +ATOM 12784 O O . THR G 1 180 ? 70.305 -47.044 37.158 1.00 166.89 ? 180 THR G O 1 +ATOM 12785 C CB . THR G 1 180 ? 70.120 -47.637 34.058 1.00 155.89 ? 180 THR G CB 1 +ATOM 12786 O OG1 . THR G 1 180 ? 69.729 -48.922 34.566 1.00 185.94 ? 180 THR G OG1 1 +ATOM 12787 C CG2 . THR G 1 180 ? 71.642 -47.546 34.048 1.00 193.20 ? 180 THR G CG2 1 +ATOM 12788 N N . ILE G 1 181 ? 68.111 -47.355 36.733 1.00 132.72 ? 181 ILE G N 1 +ATOM 12789 C CA . ILE G 1 181 ? 67.801 -47.867 38.076 1.00 158.71 ? 181 ILE G CA 1 +ATOM 12790 C C . ILE G 1 181 ? 67.699 -49.402 38.081 1.00 173.11 ? 181 ILE G C 1 +ATOM 12791 O O . ILE G 1 181 ? 66.846 -49.972 37.405 1.00 187.67 ? 181 ILE G O 1 +ATOM 12792 C CB . ILE G 1 181 ? 66.485 -47.255 38.618 1.00 161.62 ? 181 ILE G CB 1 +ATOM 12793 C CG1 . ILE G 1 181 ? 66.523 -45.728 38.514 1.00 180.36 ? 181 ILE G CG1 1 +ATOM 12794 C CG2 . ILE G 1 181 ? 66.232 -47.656 40.066 1.00 124.29 ? 181 ILE G CG2 1 +ATOM 12795 C CD1 . ILE G 1 181 ? 65.440 -45.149 37.627 1.00 196.09 ? 181 ILE G CD1 1 +ATOM 12796 N N . LEU G 1 182 ? 68.581 -50.050 38.845 1.00 186.77 ? 182 LEU G N 1 +ATOM 12797 C CA . LEU G 1 182 ? 68.668 -51.515 38.908 1.00 175.30 ? 182 LEU G CA 1 +ATOM 12798 C C . LEU G 1 182 ? 67.840 -52.138 40.038 1.00 147.24 ? 182 LEU G C 1 +ATOM 12799 O O . LEU G 1 182 ? 67.851 -51.661 41.175 1.00 98.43 ? 182 LEU G O 1 +ATOM 12800 C CB . LEU G 1 182 ? 70.130 -51.944 39.071 1.00 172.88 ? 182 LEU G CB 1 +ATOM 12801 C CG . LEU G 1 182 ? 70.370 -53.452 39.167 1.00 171.50 ? 182 LEU G CG 1 +ATOM 12802 C CD1 . LEU G 1 182 ? 69.934 -54.201 37.912 1.00 136.41 ? 182 LEU G CD1 1 +ATOM 12803 C CD2 . LEU G 1 182 ? 71.840 -53.678 39.471 1.00 199.84 ? 182 LEU G CD2 1 +ATOM 12804 N N . SER G 1 183 ? 67.203 -53.260 39.721 1.00 146.50 ? 183 SER G N 1 +ATOM 12805 C CA . SER G 1 183 ? 66.490 -54.056 40.710 1.00 152.06 ? 183 SER G CA 1 +ATOM 12806 C C . SER G 1 183 ? 66.722 -55.546 40.460 1.00 140.84 ? 183 SER G C 1 +ATOM 12807 O O . SER G 1 183 ? 66.760 -55.983 39.303 1.00 150.63 ? 183 SER G O 1 +ATOM 12808 C CB . SER G 1 183 ? 64.991 -53.746 40.640 1.00 197.87 ? 183 SER G CB 1 +ATOM 12809 O OG . SER G 1 183 ? 64.759 -52.367 40.391 1.00 238.70 ? 183 SER G OG 1 +ATOM 12810 N N . TYR G 1 184 ? 66.860 -56.326 41.533 1.00 135.97 ? 184 TYR G N 1 +ATOM 12811 C CA . TYR G 1 184 ? 67.034 -57.787 41.410 1.00 136.65 ? 184 TYR G CA 1 +ATOM 12812 C C . TYR G 1 184 ? 66.573 -58.604 42.631 1.00 112.24 ? 184 TYR G C 1 +ATOM 12813 O O . TYR G 1 184 ? 66.466 -58.090 43.750 1.00 81.52 ? 184 TYR G O 1 +ATOM 12814 C CB . TYR G 1 184 ? 68.486 -58.164 41.063 1.00 120.06 ? 184 TYR G CB 1 +ATOM 12815 C CG . TYR G 1 184 ? 69.510 -57.733 42.074 1.00 113.22 ? 184 TYR G CG 1 +ATOM 12816 C CD1 . TYR G 1 184 ? 69.713 -58.458 43.251 1.00 111.23 ? 184 TYR G CD1 1 +ATOM 12817 C CD2 . TYR G 1 184 ? 70.242 -56.570 41.883 1.00 111.03 ? 184 TYR G CD2 1 +ATOM 12818 C CE1 . TYR G 1 184 ? 70.641 -58.056 44.193 1.00 134.92 ? 184 TYR G CE1 1 +ATOM 12819 C CE2 . TYR G 1 184 ? 71.135 -56.134 42.841 1.00 123.54 ? 184 TYR G CE2 1 +ATOM 12820 C CZ . TYR G 1 184 ? 71.347 -56.888 43.982 1.00 145.25 ? 184 TYR G CZ 1 +ATOM 12821 O OH . TYR G 1 184 ? 72.219 -56.430 44.952 1.00 172.01 ? 184 TYR G OH 1 +ATOM 12822 N N . GLU G 1 185 ? 66.203 -59.850 42.344 1.00 115.42 ? 185 GLU G N 1 +ATOM 12823 C CA . GLU G 1 185 ? 65.599 -60.749 43.328 1.00 126.94 ? 185 GLU G CA 1 +ATOM 12824 C C . GLU G 1 185 ? 66.242 -62.102 43.239 1.00 142.76 ? 185 GLU G C 1 +ATOM 12825 O O . GLU G 1 185 ? 66.081 -62.813 42.246 1.00 159.80 ? 185 GLU G O 1 +ATOM 12826 C CB . GLU G 1 185 ? 64.085 -60.946 43.136 1.00 157.24 ? 185 GLU G CB 1 +ATOM 12827 C CG . GLU G 1 185 ? 63.268 -59.707 42.826 1.00 174.38 ? 185 GLU G CG 1 +ATOM 12828 C CD . GLU G 1 185 ? 61.774 -59.992 42.880 1.00 163.21 ? 185 GLU G CD 1 +ATOM 12829 O OE1 . GLU G 1 185 ? 61.392 -61.163 43.108 1.00 142.71 ? 185 GLU G OE1 1 +ATOM 12830 O OE2 . GLU G 1 185 ? 60.982 -59.043 42.707 1.00 179.39 ? 185 GLU G OE2 1 +ATOM 12831 N N . VAL G 1 186 ? 66.983 -62.446 44.277 1.00 158.50 ? 186 VAL G N 1 +ATOM 12832 C CA . VAL G 1 186 ? 67.650 -63.730 44.368 1.00 161.90 ? 186 VAL G CA 1 +ATOM 12833 C C . VAL G 1 186 ? 66.887 -64.625 45.324 1.00 149.09 ? 186 VAL G C 1 +ATOM 12834 O O . VAL G 1 186 ? 66.378 -64.180 46.353 1.00 121.74 ? 186 VAL G O 1 +ATOM 12835 C CB . VAL G 1 186 ? 69.092 -63.577 44.874 1.00 178.48 ? 186 VAL G CB 1 +ATOM 12836 C CG1 . VAL G 1 186 ? 69.827 -64.905 44.783 1.00 214.03 ? 186 VAL G CG1 1 +ATOM 12837 C CG2 . VAL G 1 186 ? 69.829 -62.510 44.080 1.00 178.19 ? 186 VAL G CG2 1 +ATOM 12838 N N . GLN G 1 187 ? 66.767 -65.892 44.963 1.00 166.90 ? 187 GLN G N 1 +ATOM 12839 C CA . GLN G 1 187 ? 65.930 -66.774 45.732 1.00 171.66 ? 187 GLN G CA 1 +ATOM 12840 C C . GLN G 1 187 ? 66.390 -68.244 45.611 1.00 177.64 ? 187 GLN G C 1 +ATOM 12841 O O . GLN G 1 187 ? 66.822 -68.699 44.539 1.00 163.76 ? 187 GLN G O 1 +ATOM 12842 C CB . GLN G 1 187 ? 64.480 -66.538 45.335 1.00 155.38 ? 187 GLN G CB 1 +ATOM 12843 C CG . GLN G 1 187 ? 63.520 -67.476 46.005 1.00 133.17 ? 187 GLN G CG 1 +ATOM 12844 C CD . GLN G 1 187 ? 62.108 -67.281 45.514 1.00 136.46 ? 187 GLN G CD 1 +ATOM 12845 O OE1 . GLN G 1 187 ? 61.892 -66.932 44.358 1.00 143.63 ? 187 GLN G OE1 1 +ATOM 12846 N NE2 . GLN G 1 187 ? 61.139 -67.447 46.406 1.00 124.87 ? 187 GLN G NE2 1 +ATOM 12847 N N . ALA G 1 188 ? 66.400 -68.946 46.745 1.00 161.56 ? 188 ALA G N 1 +ATOM 12848 C CA . ALA G 1 188 ? 66.835 -70.344 46.774 1.00 135.45 ? 188 ALA G CA 1 +ATOM 12849 C C . ALA G 1 188 ? 65.985 -71.159 47.744 1.00 131.09 ? 188 ALA G C 1 +ATOM 12850 O O . ALA G 1 188 ? 65.598 -70.670 48.792 1.00 96.98 ? 188 ALA G O 1 +ATOM 12851 C CB . ALA G 1 188 ? 68.303 -70.436 47.161 1.00 144.57 ? 188 ALA G CB 1 +ATOM 12852 N N . GLY G 1 189 ? 65.677 -72.394 47.371 1.00 152.21 ? 189 GLY G N 1 +ATOM 12853 C CA . GLY G 1 189 ? 64.884 -73.276 48.214 1.00 161.19 ? 189 GLY G CA 1 +ATOM 12854 C C . GLY G 1 189 ? 65.319 -74.729 48.106 1.00 198.39 ? 189 GLY G C 1 +ATOM 12855 O O . GLY G 1 189 ? 65.597 -75.230 47.013 1.00 172.06 ? 189 GLY G O 1 +ATOM 12856 N N . VAL G 1 190 ? 65.347 -75.416 49.243 1.00 212.43 ? 190 VAL G N 1 +ATOM 12857 C CA . VAL G 1 190 ? 65.653 -76.848 49.282 1.00 196.50 ? 190 VAL G CA 1 +ATOM 12858 C C . VAL G 1 190 ? 64.435 -77.642 49.764 1.00 177.90 ? 190 VAL G C 1 +ATOM 12859 O O . VAL G 1 190 ? 63.740 -77.221 50.691 1.00 113.41 ? 190 VAL G O 1 +ATOM 12860 C CB . VAL G 1 190 ? 66.842 -77.132 50.213 1.00 191.90 ? 190 VAL G CB 1 +ATOM 12861 C CG1 . VAL G 1 190 ? 67.307 -78.566 50.047 1.00 180.69 ? 190 VAL G CG1 1 +ATOM 12862 C CG2 . VAL G 1 190 ? 67.982 -76.149 49.947 1.00 181.40 ? 190 VAL G CG2 1 +ATOM 12863 N N . PHE G 1 191 ? 64.136 -78.745 49.082 1.00 196.62 ? 191 PHE G N 1 +ATOM 12864 C CA . PHE G 1 191 ? 62.870 -79.455 49.285 1.00 220.44 ? 191 PHE G CA 1 +ATOM 12865 C C . PHE G 1 191 ? 63.124 -80.952 49.418 1.00 211.98 ? 191 PHE G C 1 +ATOM 12866 O O . PHE G 1 191 ? 63.822 -81.535 48.584 1.00 217.48 ? 191 PHE G O 1 +ATOM 12867 C CB . PHE G 1 191 ? 61.896 -79.167 48.122 1.00 220.40 ? 191 PHE G CB 1 +ATOM 12868 C CG . PHE G 1 191 ? 60.450 -79.408 48.456 1.00 197.94 ? 191 PHE G CG 1 +ATOM 12869 C CD1 . PHE G 1 191 ? 59.962 -80.698 48.592 1.00 175.36 ? 191 PHE G CD1 1 +ATOM 12870 C CD2 . PHE G 1 191 ? 59.568 -78.342 48.607 1.00 195.21 ? 191 PHE G CD2 1 +ATOM 12871 C CE1 . PHE G 1 191 ? 58.629 -80.924 48.886 1.00 180.16 ? 191 PHE G CE1 1 +ATOM 12872 C CE2 . PHE G 1 191 ? 58.236 -78.562 48.912 1.00 199.02 ? 191 PHE G CE2 1 +ATOM 12873 C CZ . PHE G 1 191 ? 57.762 -79.856 49.041 1.00 185.16 ? 191 PHE G CZ 1 +ATOM 12874 N N . LEU G 1 200 ? 61.103 -82.121 54.574 1.00 155.94 ? 200 LEU G N 1 +ATOM 12875 C CA . LEU G 1 200 ? 62.037 -81.000 54.670 1.00 204.34 ? 200 LEU G CA 1 +ATOM 12876 C C . LEU G 1 200 ? 61.812 -79.986 53.558 1.00 210.57 ? 200 LEU G C 1 +ATOM 12877 O O . LEU G 1 200 ? 62.061 -80.277 52.385 1.00 153.96 ? 200 LEU G O 1 +ATOM 12878 C CB . LEU G 1 200 ? 63.494 -81.480 54.608 1.00 215.86 ? 200 LEU G CB 1 +ATOM 12879 C CG . LEU G 1 200 ? 64.540 -80.350 54.496 1.00 200.18 ? 200 LEU G CG 1 +ATOM 12880 C CD1 . LEU G 1 200 ? 65.173 -80.090 55.858 1.00 189.10 ? 200 LEU G CD1 1 +ATOM 12881 C CD2 . LEU G 1 200 ? 65.604 -80.615 53.430 1.00 161.00 ? 200 LEU G CD2 1 +ATOM 12882 N N . GLU G 1 201 ? 61.380 -78.785 53.945 1.00 210.54 ? 201 GLU G N 1 +ATOM 12883 C CA . GLU G 1 201 ? 61.505 -77.605 53.095 1.00 183.94 ? 201 GLU G CA 1 +ATOM 12884 C C . GLU G 1 201 ? 62.349 -76.532 53.781 1.00 162.92 ? 201 GLU G C 1 +ATOM 12885 O O . GLU G 1 201 ? 62.331 -76.412 55.002 1.00 110.15 ? 201 GLU G O 1 +ATOM 12886 C CB . GLU G 1 201 ? 60.128 -77.036 52.745 1.00 166.77 ? 201 GLU G CB 1 +ATOM 12887 C CG . GLU G 1 201 ? 60.152 -76.144 51.508 1.00 153.96 ? 201 GLU G CG 1 +ATOM 12888 C CD . GLU G 1 201 ? 58.795 -75.578 51.135 1.00 157.97 ? 201 GLU G CD 1 +ATOM 12889 O OE1 . GLU G 1 201 ? 57.817 -76.355 51.061 1.00 187.73 ? 201 GLU G OE1 1 +ATOM 12890 O OE2 . GLU G 1 201 ? 58.702 -74.345 50.937 1.00 141.32 ? 201 GLU G OE2 1 +ATOM 12891 N N . GLY G 1 202 ? 63.086 -75.758 52.987 1.00 157.19 ? 202 GLY G N 1 +ATOM 12892 C CA . GLY G 1 202 ? 63.825 -74.601 53.490 1.00 150.20 ? 202 GLY G CA 1 +ATOM 12893 C C . GLY G 1 202 ? 63.997 -73.563 52.384 1.00 152.38 ? 202 GLY G C 1 +ATOM 12894 O O . GLY G 1 202 ? 64.542 -73.884 51.321 1.00 108.78 ? 202 GLY G O 1 +ATOM 12895 N N . GLU G 1 203 ? 63.613 -72.318 52.661 1.00 156.85 ? 203 GLU G N 1 +ATOM 12896 C CA . GLU G 1 203 ? 63.671 -71.265 51.629 1.00 150.71 ? 203 GLU G CA 1 +ATOM 12897 C C . GLU G 1 203 ? 64.337 -69.968 52.106 1.00 130.79 ? 203 GLU G C 1 +ATOM 12898 O O . GLU G 1 203 ? 64.042 -69.449 53.181 1.00 77.43 ? 203 GLU G O 1 +ATOM 12899 C CB . GLU G 1 203 ? 62.300 -70.850 51.067 1.00 162.39 ? 203 GLU G CB 1 +ATOM 12900 C CG . GLU G 1 203 ? 61.270 -70.429 52.110 1.00 172.21 ? 203 GLU G CG 1 +ATOM 12901 C CD . GLU G 1 203 ? 59.965 -69.865 51.520 1.00 165.92 ? 203 GLU G CD 1 +ATOM 12902 O OE1 . GLU G 1 203 ? 59.909 -69.592 50.303 1.00 171.01 ? 203 GLU G OE1 1 +ATOM 12903 O OE2 . GLU G 1 203 ? 58.986 -69.659 52.285 1.00 176.18 ? 203 GLU G OE2 1 +ATOM 12904 N N . VAL G 1 204 ? 65.204 -69.422 51.260 1.00 143.29 ? 204 VAL G N 1 +ATOM 12905 C CA . VAL G 1 204 ? 65.837 -68.121 51.478 1.00 172.48 ? 204 VAL G CA 1 +ATOM 12906 C C . VAL G 1 204 ? 65.550 -67.223 50.275 1.00 178.85 ? 204 VAL G C 1 +ATOM 12907 O O . VAL G 1 204 ? 65.647 -67.662 49.125 1.00 157.84 ? 204 VAL G O 1 +ATOM 12908 C CB . VAL G 1 204 ? 67.367 -68.280 51.694 1.00 173.50 ? 204 VAL G CB 1 +ATOM 12909 C CG1 . VAL G 1 204 ? 68.113 -66.956 51.545 1.00 165.32 ? 204 VAL G CG1 1 +ATOM 12910 C CG2 . VAL G 1 204 ? 67.631 -68.888 53.064 1.00 155.07 ? 204 VAL G CG2 1 +ATOM 12911 N N . GLY G 1 205 ? 65.225 -65.960 50.550 1.00 158.04 ? 205 GLY G N 1 +ATOM 12912 C CA . GLY G 1 205 ? 65.040 -64.965 49.501 1.00 136.82 ? 205 GLY G CA 1 +ATOM 12913 C C . GLY G 1 205 ? 65.671 -63.619 49.839 1.00 106.70 ? 205 GLY G C 1 +ATOM 12914 O O . GLY G 1 205 ? 65.806 -63.260 51.003 1.00 73.71 ? 205 GLY G O 1 +ATOM 12915 N N . TYR G 1 206 ? 66.074 -62.881 48.814 1.00 108.06 ? 206 TYR G N 1 +ATOM 12916 C CA . TYR G 1 206 ? 66.598 -61.524 48.985 1.00 126.64 ? 206 TYR G CA 1 +ATOM 12917 C C . TYR G 1 206 ? 66.220 -60.679 47.784 1.00 135.69 ? 206 TYR G C 1 +ATOM 12918 O O . TYR G 1 206 ? 66.300 -61.152 46.651 1.00 145.18 ? 206 TYR G O 1 +ATOM 12919 C CB . TYR G 1 206 ? 68.137 -61.541 49.142 1.00 149.92 ? 206 TYR G CB 1 +ATOM 12920 C CG . TYR G 1 206 ? 68.779 -60.147 49.240 1.00 136.94 ? 206 TYR G CG 1 +ATOM 12921 C CD1 . TYR G 1 206 ? 68.703 -59.393 50.421 1.00 91.19 ? 206 TYR G CD1 1 +ATOM 12922 C CD2 . TYR G 1 206 ? 69.466 -59.599 48.153 1.00 139.75 ? 206 TYR G CD2 1 +ATOM 12923 C CE1 . TYR G 1 206 ? 69.282 -58.146 50.521 1.00 65.06 ? 206 TYR G CE1 1 +ATOM 12924 C CE2 . TYR G 1 206 ? 70.058 -58.351 48.244 1.00 120.11 ? 206 TYR G CE2 1 +ATOM 12925 C CZ . TYR G 1 206 ? 69.951 -57.628 49.428 1.00 93.33 ? 206 TYR G CZ 1 +ATOM 12926 O OH . TYR G 1 206 ? 70.506 -56.366 49.471 1.00 124.60 ? 206 TYR G OH 1 +ATOM 12927 N N . THR G 1 207 ? 65.903 -59.409 48.015 1.00 118.13 ? 207 THR G N 1 +ATOM 12928 C CA . THR G 1 207 ? 65.616 -58.490 46.913 1.00 130.03 ? 207 THR G CA 1 +ATOM 12929 C C . THR G 1 207 ? 66.271 -57.114 47.130 1.00 93.07 ? 207 THR G C 1 +ATOM 12930 O O . THR G 1 207 ? 66.243 -56.571 48.242 1.00 46.96 ? 207 THR G O 1 +ATOM 12931 C CB . THR G 1 207 ? 64.093 -58.308 46.746 1.00 160.93 ? 207 THR G CB 1 +ATOM 12932 O OG1 . THR G 1 207 ? 63.547 -57.740 47.941 1.00 180.60 ? 207 THR G OG1 1 +ATOM 12933 C CG2 . THR G 1 207 ? 63.414 -59.639 46.488 1.00 170.13 ? 207 THR G CG2 1 +ATOM 12934 N N . SER G 1 208 ? 66.825 -56.538 46.059 1.00 81.03 ? 208 SER G N 1 +ATOM 12935 C CA . SER G 1 208 ? 67.401 -55.192 46.150 1.00 103.90 ? 208 SER G CA 1 +ATOM 12936 C C . SER G 1 208 ? 66.962 -54.266 45.018 1.00 132.38 ? 208 SER G C 1 +ATOM 12937 O O . SER G 1 208 ? 67.113 -54.594 43.836 1.00 103.05 ? 208 SER G O 1 +ATOM 12938 C CB . SER G 1 208 ? 68.924 -55.267 46.185 1.00 111.20 ? 208 SER G CB 1 +ATOM 12939 O OG . SER G 1 208 ? 69.530 -53.980 46.126 1.00 86.72 ? 208 SER G OG 1 +ATOM 12940 N N . ASN G 1 209 ? 66.473 -53.088 45.406 1.00 159.89 ? 209 ASN G N 1 +ATOM 12941 C CA . ASN G 1 209 ? 66.157 -52.012 44.472 1.00 156.21 ? 209 ASN G CA 1 +ATOM 12942 C C . ASN G 1 209 ? 67.088 -50.835 44.680 1.00 141.24 ? 209 ASN G C 1 +ATOM 12943 O O . ASN G 1 209 ? 67.348 -50.442 45.816 1.00 94.60 ? 209 ASN G O 1 +ATOM 12944 C CB . ASN G 1 209 ? 64.730 -51.517 44.689 1.00 143.33 ? 209 ASN G CB 1 +ATOM 12945 C CG . ASN G 1 209 ? 63.699 -52.524 44.267 1.00 146.52 ? 209 ASN G CG 1 +ATOM 12946 O OD1 . ASN G 1 209 ? 63.366 -52.636 43.087 1.00 161.92 ? 209 ASN G OD1 1 +ATOM 12947 N ND2 . ASN G 1 209 ? 63.180 -53.263 45.231 1.00 141.96 ? 209 ASN G ND2 1 +ATOM 12948 N N . GLU G 1 210 ? 67.564 -50.258 43.580 1.00 133.98 ? 210 GLU G N 1 +ATOM 12949 C CA . GLU G 1 210 ? 68.241 -48.978 43.654 1.00 116.04 ? 210 GLU G CA 1 +ATOM 12950 C C . GLU G 1 210 ? 67.208 -47.944 44.049 1.00 118.18 ? 210 GLU G C 1 +ATOM 12951 O O . GLU G 1 210 ? 66.061 -47.985 43.602 1.00 142.74 ? 210 GLU G O 1 +ATOM 12952 C CB . GLU G 1 210 ? 68.874 -48.605 42.318 1.00 103.15 ? 210 GLU G CB 1 +ATOM 12953 C CG . GLU G 1 210 ? 70.287 -48.035 42.417 1.00 90.91 ? 210 GLU G CG 1 +ATOM 12954 C CD . GLU G 1 210 ? 71.026 -48.093 41.080 1.00 133.93 ? 210 GLU G CD 1 +ATOM 12955 O OE1 . GLU G 1 210 ? 70.709 -48.960 40.190 1.00 231.30 ? 210 GLU G OE1 1 +ATOM 12956 O OE2 . GLU G 1 210 ? 71.906 -47.230 40.866 1.00 87.74 ? 210 GLU G OE2 1 +ATOM 12957 N N . PRO G 1 211 ? 67.596 -47.017 44.912 1.00 113.47 ? 211 PRO G N 1 +ATOM 12958 C CA . PRO G 1 211 ? 66.731 -45.880 45.142 1.00 131.66 ? 211 PRO G CA 1 +ATOM 12959 C C . PRO G 1 211 ? 66.653 -44.929 43.922 1.00 157.91 ? 211 PRO G C 1 +ATOM 12960 O O . PRO G 1 211 ? 67.672 -44.431 43.440 1.00 132.42 ? 211 PRO G O 1 +ATOM 12961 C CB . PRO G 1 211 ? 67.379 -45.186 46.346 1.00 140.68 ? 211 PRO G CB 1 +ATOM 12962 C CG . PRO G 1 211 ? 68.302 -46.186 46.932 1.00 129.00 ? 211 PRO G CG 1 +ATOM 12963 C CD . PRO G 1 211 ? 68.786 -46.977 45.763 1.00 127.86 ? 211 PRO G CD 1 +ATOM 12964 N N . VAL G 1 212 ? 65.434 -44.665 43.460 1.00 163.74 ? 212 VAL G N 1 +ATOM 12965 C CA . VAL G 1 212 ? 65.204 -43.741 42.352 1.00 137.64 ? 212 VAL G CA 1 +ATOM 12966 C C . VAL G 1 212 ? 65.713 -42.358 42.779 1.00 115.70 ? 212 VAL G C 1 +ATOM 12967 O O . VAL G 1 212 ? 66.262 -41.595 42.000 1.00 75.44 ? 212 VAL G O 1 +ATOM 12968 C CB . VAL G 1 212 ? 63.687 -43.687 41.972 1.00 123.77 ? 212 VAL G CB 1 +ATOM 12969 C CG1 . VAL G 1 212 ? 63.484 -42.830 40.724 1.00 106.07 ? 212 VAL G CG1 1 +ATOM 12970 C CG2 . VAL G 1 212 ? 63.115 -45.086 41.763 1.00 114.77 ? 212 VAL G CG2 1 +ATOM 12971 N N . MET G 1 213 ? 65.352 -42.016 44.008 1.00 108.59 ? 213 MET G N 1 +ATOM 12972 C CA . MET G 1 213 ? 65.873 -40.876 44.744 1.00 90.84 ? 213 MET G CA 1 +ATOM 12973 C C . MET G 1 213 ? 67.334 -40.617 44.413 1.00 79.30 ? 213 MET G C 1 +ATOM 12974 O O . MET G 1 213 ? 67.752 -39.497 44.142 1.00 86.93 ? 213 MET G O 1 +ATOM 12975 C CB . MET G 1 213 ? 65.668 -41.257 46.223 1.00 104.98 ? 213 MET G CB 1 +ATOM 12976 C CG . MET G 1 213 ? 66.038 -40.267 47.294 1.00 110.99 ? 213 MET G CG 1 +ATOM 12977 S SD . MET G 1 213 ? 65.659 -41.117 48.883 1.00 177.40 ? 213 MET G SD 1 +ATOM 12978 C CE . MET G 1 213 ? 67.337 -41.272 49.422 1.00 193.36 ? 213 MET G CE 1 +ATOM 12979 N N . LEU G 1 214 ? 68.117 -41.676 44.491 1.00 105.32 ? 214 LEU G N 1 +ATOM 12980 C CA . LEU G 1 214 ? 69.574 -41.575 44.573 1.00 128.63 ? 214 LEU G CA 1 +ATOM 12981 C C . LEU G 1 214 ? 70.096 -41.497 43.161 1.00 108.79 ? 214 LEU G C 1 +ATOM 12982 O O . LEU G 1 214 ? 71.148 -40.896 42.908 1.00 109.86 ? 214 LEU G O 1 +ATOM 12983 C CB . LEU G 1 214 ? 70.167 -42.795 45.320 1.00 126.36 ? 214 LEU G CB 1 +ATOM 12984 C CG . LEU G 1 214 ? 71.300 -42.579 46.325 1.00 112.08 ? 214 LEU G CG 1 +ATOM 12985 C CD1 . LEU G 1 214 ? 70.910 -41.618 47.474 1.00 115.95 ? 214 LEU G CD1 1 +ATOM 12986 C CD2 . LEU G 1 214 ? 71.756 -43.933 46.874 1.00 98.61 ? 214 LEU G CD2 1 +ATOM 12987 N N . CYS G 1 215 ? 69.323 -42.062 42.243 1.00 79.10 ? 215 CYS G N 1 +ATOM 12988 C CA . CYS G 1 215 ? 69.707 -42.038 40.844 1.00 105.16 ? 215 CYS G CA 1 +ATOM 12989 C C . CYS G 1 215 ? 69.458 -40.645 40.291 1.00 86.45 ? 215 CYS G C 1 +ATOM 12990 O O . CYS G 1 215 ? 70.229 -40.121 39.437 1.00 76.74 ? 215 CYS G O 1 +ATOM 12991 C CB . CYS G 1 215 ? 68.895 -43.069 40.058 1.00 124.33 ? 215 CYS G CB 1 +ATOM 12992 S SG . CYS G 1 215 ? 69.242 -44.769 40.505 1.00 126.90 ? 215 CYS G SG 1 +ATOM 12993 N N . LEU G 1 216 ? 68.344 -40.076 40.725 1.00 69.55 ? 216 LEU G N 1 +ATOM 12994 C CA . LEU G 1 216 ? 68.009 -38.732 40.305 1.00 103.85 ? 216 LEU G CA 1 +ATOM 12995 C C . LEU G 1 216 ? 69.127 -37.796 40.747 1.00 117.73 ? 216 LEU G C 1 +ATOM 12996 O O . LEU G 1 216 ? 69.630 -36.986 39.964 1.00 89.90 ? 216 LEU G O 1 +ATOM 12997 C CB . LEU G 1 216 ? 66.672 -38.305 40.916 1.00 124.10 ? 216 LEU G CB 1 +ATOM 12998 C CG . LEU G 1 216 ? 66.238 -36.853 40.609 1.00 106.87 ? 216 LEU G CG 1 +ATOM 12999 C CD1 . LEU G 1 216 ? 66.142 -36.553 39.109 1.00 71.50 ? 216 LEU G CD1 1 +ATOM 13000 C CD2 . LEU G 1 216 ? 64.915 -36.552 41.307 1.00 82.93 ? 216 LEU G CD2 1 +ATOM 13001 N N . MET G 1 217 ? 69.546 -37.955 42.001 1.00 147.07 ? 217 MET G N 1 +ATOM 13002 C CA . MET G 1 217 ? 70.575 -37.089 42.575 1.00 141.51 ? 217 MET G CA 1 +ATOM 13003 C C . MET G 1 217 ? 71.897 -37.212 41.815 1.00 115.26 ? 217 MET G C 1 +ATOM 13004 O O . MET G 1 217 ? 72.471 -36.221 41.402 1.00 78.48 ? 217 MET G O 1 +ATOM 13005 C CB . MET G 1 217 ? 70.779 -37.414 44.060 1.00 156.94 ? 217 MET G CB 1 +ATOM 13006 C CG . MET G 1 217 ? 70.893 -36.176 44.931 1.00 174.09 ? 217 MET G CG 1 +ATOM 13007 S SD . MET G 1 217 ? 72.416 -35.260 44.628 1.00 180.68 ? 217 MET G SD 1 +ATOM 13008 C CE . MET G 1 217 ? 72.142 -33.747 45.551 1.00 198.15 ? 217 MET G CE 1 +ATOM 13009 N N . SER G 1 218 ? 72.304 -38.453 41.558 1.00 106.70 ? 218 SER G N 1 +ATOM 13010 C CA . SER G 1 218 ? 73.490 -38.743 40.776 1.00 94.24 ? 218 SER G CA 1 +ATOM 13011 C C . SER G 1 218 ? 73.462 -38.036 39.414 1.00 104.95 ? 218 SER G C 1 +ATOM 13012 O O . SER G 1 218 ? 74.424 -37.378 39.009 1.00 99.41 ? 218 SER G O 1 +ATOM 13013 C CB . SER G 1 218 ? 73.628 -40.269 40.587 1.00 79.44 ? 218 SER G CB 1 +ATOM 13014 O OG . SER G 1 218 ? 74.906 -40.586 40.048 1.00 122.41 ? 218 SER G OG 1 +ATOM 13015 N N . ALA G 1 219 ? 72.368 -38.224 38.682 1.00 115.00 ? 219 ALA G N 1 +ATOM 13016 C CA . ALA G 1 219 ? 72.274 -37.724 37.319 1.00 110.03 ? 219 ALA G CA 1 +ATOM 13017 C C . ALA G 1 219 ? 72.328 -36.180 37.309 1.00 133.74 ? 219 ALA G C 1 +ATOM 13018 O O . ALA G 1 219 ? 72.856 -35.557 36.373 1.00 110.87 ? 219 ALA G O 1 +ATOM 13019 C CB . ALA G 1 219 ? 71.002 -38.251 36.670 1.00 94.70 ? 219 ALA G CB 1 +ATOM 13020 N N . ILE G 1 220 ? 71.769 -35.557 38.344 1.00 155.42 ? 220 ILE G N 1 +ATOM 13021 C CA . ILE G 1 220 ? 71.751 -34.090 38.418 1.00 154.65 ? 220 ILE G CA 1 +ATOM 13022 C C . ILE G 1 220 ? 73.177 -33.587 38.616 1.00 133.11 ? 220 ILE G C 1 +ATOM 13023 O O . ILE G 1 220 ? 73.578 -32.582 38.039 1.00 84.31 ? 220 ILE G O 1 +ATOM 13024 C CB . ILE G 1 220 ? 70.800 -33.583 39.538 1.00 147.24 ? 220 ILE G CB 1 +ATOM 13025 C CG1 . ILE G 1 220 ? 69.343 -33.835 39.132 1.00 153.98 ? 220 ILE G CG1 1 +ATOM 13026 C CG2 . ILE G 1 220 ? 71.028 -32.098 39.818 1.00 123.01 ? 220 ILE G CG2 1 +ATOM 13027 C CD1 . ILE G 1 220 ? 68.358 -33.756 40.270 1.00 154.62 ? 220 ILE G CD1 1 +ATOM 13028 N N . GLU G 1 221 ? 73.929 -34.282 39.465 1.00 133.49 ? 221 GLU G N 1 +ATOM 13029 C CA . GLU G 1 221 ? 75.319 -33.918 39.714 1.00 114.07 ? 221 GLU G CA 1 +ATOM 13030 C C . GLU G 1 221 ? 76.085 -33.945 38.398 1.00 106.17 ? 221 GLU G C 1 +ATOM 13031 O O . GLU G 1 221 ? 76.796 -32.994 38.048 1.00 93.00 ? 221 GLU G O 1 +ATOM 13032 C CB . GLU G 1 221 ? 75.935 -34.891 40.732 1.00 106.94 ? 221 GLU G CB 1 +ATOM 13033 C CG . GLU G 1 221 ? 75.477 -34.648 42.165 1.00 129.95 ? 221 GLU G CG 1 +ATOM 13034 C CD . GLU G 1 221 ? 75.715 -35.817 43.113 1.00 131.55 ? 221 GLU G CD 1 +ATOM 13035 O OE1 . GLU G 1 221 ? 75.636 -36.995 42.685 1.00 79.66 ? 221 GLU G OE1 1 +ATOM 13036 O OE2 . GLU G 1 221 ? 76.058 -35.534 44.290 1.00 158.11 ? 221 GLU G OE2 1 +ATOM 13037 N N . THR G 1 222 ? 75.960 -35.072 37.698 1.00 104.40 ? 222 THR G N 1 +ATOM 13038 C CA . THR G 1 222 ? 76.605 -35.289 36.401 1.00 101.85 ? 222 THR G CA 1 +ATOM 13039 C C . THR G 1 222 ? 76.292 -34.139 35.462 1.00 104.18 ? 222 THR G C 1 +ATOM 13040 O O . THR G 1 222 ? 77.188 -33.599 34.798 1.00 81.00 ? 222 THR G O 1 +ATOM 13041 C CB . THR G 1 222 ? 76.102 -36.607 35.764 1.00 106.41 ? 222 THR G CB 1 +ATOM 13042 O OG1 . THR G 1 222 ? 76.634 -37.740 36.474 1.00 89.20 ? 222 THR G OG1 1 +ATOM 13043 C CG2 . THR G 1 222 ? 76.454 -36.671 34.263 1.00 93.40 ? 222 THR G CG2 1 +ATOM 13044 N N . GLY G 1 223 ? 75.010 -33.774 35.409 1.00 111.55 ? 223 GLY G N 1 +ATOM 13045 C CA . GLY G 1 223 ? 74.571 -32.646 34.597 1.00 136.23 ? 223 GLY G CA 1 +ATOM 13046 C C . GLY G 1 223 ? 75.296 -31.357 34.967 1.00 147.15 ? 223 GLY G C 1 +ATOM 13047 O O . GLY G 1 223 ? 75.633 -30.547 34.086 1.00 104.41 ? 223 GLY G O 1 +ATOM 13048 N N . VAL G 1 224 ? 75.500 -31.140 36.271 1.00 126.66 ? 224 VAL G N 1 +ATOM 13049 C CA . VAL G 1 224 ? 76.121 -29.904 36.741 1.00 101.07 ? 224 VAL G CA 1 +ATOM 13050 C C . VAL G 1 224 ? 77.553 -29.859 36.242 1.00 116.70 ? 224 VAL G C 1 +ATOM 13051 O O . VAL G 1 224 ? 78.032 -28.821 35.780 1.00 94.34 ? 224 VAL G O 1 +ATOM 13052 C CB . VAL G 1 224 ? 76.106 -29.803 38.267 1.00 81.86 ? 224 VAL G CB 1 +ATOM 13053 C CG1 . VAL G 1 224 ? 76.942 -28.613 38.703 1.00 87.33 ? 224 VAL G CG1 1 +ATOM 13054 C CG2 . VAL G 1 224 ? 74.686 -29.665 38.773 1.00 90.30 ? 224 VAL G CG2 1 +ATOM 13055 N N . ILE G 1 225 ? 78.223 -31.009 36.281 1.00 132.79 ? 225 ILE G N 1 +ATOM 13056 C CA . ILE G 1 225 ? 79.596 -31.096 35.781 1.00 118.19 ? 225 ILE G CA 1 +ATOM 13057 C C . ILE G 1 225 ? 79.645 -30.747 34.298 1.00 108.76 ? 225 ILE G C 1 +ATOM 13058 O O . ILE G 1 225 ? 80.433 -29.874 33.912 1.00 103.93 ? 225 ILE G O 1 +ATOM 13059 C CB . ILE G 1 225 ? 80.227 -32.480 36.017 1.00 97.29 ? 225 ILE G CB 1 +ATOM 13060 C CG1 . ILE G 1 225 ? 80.434 -32.712 37.517 1.00 97.01 ? 225 ILE G CG1 1 +ATOM 13061 C CG2 . ILE G 1 225 ? 81.570 -32.575 35.308 1.00 87.30 ? 225 ILE G CG2 1 +ATOM 13062 C CD1 . ILE G 1 225 ? 80.631 -34.168 37.881 1.00 106.26 ? 225 ILE G CD1 1 +ATOM 13063 N N . PHE G 1 226 ? 78.797 -31.401 33.489 1.00 79.50 ? 226 PHE G N 1 +ATOM 13064 C CA . PHE G 1 226 ? 78.759 -31.143 32.043 1.00 81.53 ? 226 PHE G CA 1 +ATOM 13065 C C . PHE G 1 226 ? 78.490 -29.664 31.758 1.00 110.47 ? 226 PHE G C 1 +ATOM 13066 O O . PHE G 1 226 ? 78.982 -29.108 30.775 1.00 97.53 ? 226 PHE G O 1 +ATOM 13067 C CB . PHE G 1 226 ? 77.715 -32.006 31.346 1.00 67.78 ? 226 PHE G CB 1 +ATOM 13068 C CG . PHE G 1 226 ? 78.163 -33.415 31.064 1.00 81.95 ? 226 PHE G CG 1 +ATOM 13069 C CD1 . PHE G 1 226 ? 79.253 -33.665 30.236 1.00 100.84 ? 226 PHE G CD1 1 +ATOM 13070 C CD2 . PHE G 1 226 ? 77.451 -34.505 31.567 1.00 95.58 ? 226 PHE G CD2 1 +ATOM 13071 C CE1 . PHE G 1 226 ? 79.674 -34.967 29.974 1.00 111.78 ? 226 PHE G CE1 1 +ATOM 13072 C CE2 . PHE G 1 226 ? 77.825 -35.803 31.262 1.00 113.43 ? 226 PHE G CE2 1 +ATOM 13073 C CZ . PHE G 1 226 ? 78.949 -36.037 30.475 1.00 130.84 ? 226 PHE G CZ 1 +ATOM 13074 N N . LEU G 1 227 ? 77.708 -29.026 32.626 1.00 143.28 ? 227 LEU G N 1 +ATOM 13075 C CA . LEU G 1 227 ? 77.401 -27.601 32.481 1.00 143.99 ? 227 LEU G CA 1 +ATOM 13076 C C . LEU G 1 227 ? 78.621 -26.745 32.736 1.00 131.30 ? 227 LEU G C 1 +ATOM 13077 O O . LEU G 1 227 ? 78.897 -25.822 31.979 1.00 123.27 ? 227 LEU G O 1 +ATOM 13078 C CB . LEU G 1 227 ? 76.283 -27.220 33.446 1.00 138.10 ? 227 LEU G CB 1 +ATOM 13079 C CG . LEU G 1 227 ? 74.856 -27.617 33.022 1.00 136.95 ? 227 LEU G CG 1 +ATOM 13080 C CD1 . LEU G 1 227 ? 73.803 -27.499 34.105 1.00 116.46 ? 227 LEU G CD1 1 +ATOM 13081 C CD2 . LEU G 1 227 ? 74.407 -26.832 31.804 1.00 136.16 ? 227 LEU G CD2 1 +ATOM 13082 N N . ILE G 1 228 ? 79.374 -27.080 33.780 1.00 130.49 ? 228 ILE G N 1 +ATOM 13083 C CA . ILE G 1 228 ? 80.577 -26.318 34.131 1.00 126.74 ? 228 ILE G CA 1 +ATOM 13084 C C . ILE G 1 228 ? 81.619 -26.469 33.037 1.00 121.69 ? 228 ILE G C 1 +ATOM 13085 O O . ILE G 1 228 ? 82.193 -25.484 32.574 1.00 88.37 ? 228 ILE G O 1 +ATOM 13086 C CB . ILE G 1 228 ? 81.207 -26.767 35.471 1.00 123.38 ? 228 ILE G CB 1 +ATOM 13087 C CG1 . ILE G 1 228 ? 80.249 -26.510 36.636 1.00 125.25 ? 228 ILE G CG1 1 +ATOM 13088 C CG2 . ILE G 1 228 ? 82.497 -26.006 35.728 1.00 102.69 ? 228 ILE G CG2 1 +ATOM 13089 C CD1 . ILE G 1 228 ? 80.606 -27.238 37.913 1.00 100.27 ? 228 ILE G CD1 1 +ATOM 13090 N N . ASN G 1 229 ? 81.842 -27.711 32.612 1.00 142.83 ? 229 ASN G N 1 +ATOM 13091 C CA . ASN G 1 229 ? 82.821 -28.006 31.567 1.00 163.57 ? 229 ASN G CA 1 +ATOM 13092 C C . ASN G 1 229 ? 82.458 -27.299 30.258 1.00 176.27 ? 229 ASN G C 1 +ATOM 13093 O O . ASN G 1 229 ? 83.309 -26.657 29.631 1.00 158.90 ? 229 ASN G O 1 +ATOM 13094 C CB . ASN G 1 229 ? 82.910 -29.520 31.345 1.00 153.43 ? 229 ASN G CB 1 +ATOM 13095 C CG . ASN G 1 229 ? 84.168 -29.938 30.608 1.00 165.79 ? 229 ASN G CG 1 +ATOM 13096 O OD1 . ASN G 1 229 ? 85.158 -29.208 30.567 1.00 142.17 ? 229 ASN G OD1 1 +ATOM 13097 N ND2 . ASN G 1 229 ? 84.106 -31.096 29.964 1.00 203.22 ? 229 ASN G ND2 1 +ATOM 13098 N N . ASP G 1 230 ? 81.176 -27.356 29.902 1.00 184.10 ? 230 ASP G N 1 +ATOM 13099 C CA . ASP G 1 230 ? 80.673 -26.674 28.724 1.00 184.58 ? 230 ASP G CA 1 +ATOM 13100 C C . ASP G 1 230 ? 80.911 -25.159 28.837 1.00 209.41 ? 230 ASP G C 1 +ATOM 13101 O O . ASP G 1 230 ? 81.282 -24.497 27.864 1.00 210.78 ? 230 ASP G O 1 +ATOM 13102 C CB . ASP G 1 230 ? 79.184 -26.977 28.543 1.00 163.58 ? 230 ASP G CB 1 +ATOM 13103 C CG . ASP G 1 230 ? 78.637 -26.450 27.236 1.00 188.01 ? 230 ASP G CG 1 +ATOM 13104 O OD1 . ASP G 1 230 ? 79.030 -27.011 26.180 1.00 103.81 ? 230 ASP G OD1 1 +ATOM 13105 O OD2 . ASP G 1 230 ? 77.878 -25.414 27.267 1.00 276.30 ? 230 ASP G OD2 1 +ATOM 13106 N N . GLY G 1 231 ? 80.668 -24.604 30.021 1.00 206.41 ? 231 GLY G N 1 +ATOM 13107 C CA . GLY G 1 231 ? 80.847 -23.170 30.239 1.00 198.12 ? 231 GLY G CA 1 +ATOM 13108 C C . GLY G 1 231 ? 82.309 -22.760 30.150 1.00 175.15 ? 231 GLY G C 1 +ATOM 13109 O O . GLY G 1 231 ? 82.629 -21.650 29.699 1.00 117.58 ? 231 GLY G O 1 +ATOM 13110 N N . ILE G 1 232 ? 83.191 -23.641 30.622 1.00 176.43 ? 232 ILE G N 1 +ATOM 13111 C CA . ILE G 1 232 ? 84.631 -23.413 30.524 1.00 161.47 ? 232 ILE G CA 1 +ATOM 13112 C C . ILE G 1 232 ? 85.024 -23.298 29.059 1.00 155.90 ? 232 ILE G C 1 +ATOM 13113 O O . ILE G 1 232 ? 85.707 -22.349 28.671 1.00 126.44 ? 232 ILE G O 1 +ATOM 13114 C CB . ILE G 1 232 ? 85.436 -24.542 31.207 1.00 159.35 ? 232 ILE G CB 1 +ATOM 13115 C CG1 . ILE G 1 232 ? 85.322 -24.410 32.732 1.00 150.38 ? 232 ILE G CG1 1 +ATOM 13116 C CG2 . ILE G 1 232 ? 86.902 -24.516 30.771 1.00 178.10 ? 232 ILE G CG2 1 +ATOM 13117 C CD1 . ILE G 1 232 ? 85.701 -25.665 33.489 1.00 143.47 ? 232 ILE G CD1 1 +ATOM 13118 N N . ASP G 1 233 ? 84.592 -24.273 28.259 1.00 167.52 ? 233 ASP G N 1 +ATOM 13119 C CA . ASP G 1 233 ? 84.869 -24.283 26.826 1.00 162.92 ? 233 ASP G CA 1 +ATOM 13120 C C . ASP G 1 233 ? 84.367 -22.994 26.184 1.00 151.74 ? 233 ASP G C 1 +ATOM 13121 O O . ASP G 1 233 ? 85.083 -22.362 25.401 1.00 168.96 ? 233 ASP G O 1 +ATOM 13122 C CB . ASP G 1 233 ? 84.205 -25.498 26.149 1.00 172.21 ? 233 ASP G CB 1 +ATOM 13123 C CG . ASP G 1 233 ? 84.794 -26.835 26.606 1.00 162.16 ? 233 ASP G CG 1 +ATOM 13124 O OD1 . ASP G 1 233 ? 85.598 -26.848 27.559 1.00 141.17 ? 233 ASP G OD1 1 +ATOM 13125 O OD2 . ASP G 1 233 ? 84.469 -27.870 25.979 1.00 147.25 ? 233 ASP G OD2 1 +ATOM 13126 N N . ARG G 1 234 ? 83.126 -22.618 26.488 1.00 154.91 ? 234 ARG G N 1 +ATOM 13127 C CA . ARG G 1 234 ? 82.459 -21.507 25.791 1.00 164.50 ? 234 ARG G CA 1 +ATOM 13128 C C . ARG G 1 234 ? 82.796 -20.125 26.359 1.00 125.17 ? 234 ARG G C 1 +ATOM 13129 O O . ARG G 1 234 ? 82.356 -19.104 25.813 1.00 77.50 ? 234 ARG G O 1 +ATOM 13130 C CB . ARG G 1 234 ? 80.943 -21.704 25.800 1.00 158.79 ? 234 ARG G CB 1 +ATOM 13131 C CG . ARG G 1 234 ? 80.502 -22.796 24.858 1.00 149.29 ? 234 ARG G CG 1 +ATOM 13132 C CD . ARG G 1 234 ? 79.141 -23.329 25.215 1.00 143.11 ? 234 ARG G CD 1 +ATOM 13133 N NE . ARG G 1 234 ? 78.796 -24.414 24.298 1.00 192.47 ? 234 ARG G NE 1 +ATOM 13134 C CZ . ARG G 1 234 ? 77.702 -24.446 23.534 1.00 207.92 ? 234 ARG G CZ 1 +ATOM 13135 N NH1 . ARG G 1 234 ? 76.791 -23.481 23.612 1.00 146.56 ? 234 ARG G NH1 1 +ATOM 13136 N NH2 . ARG G 1 234 ? 77.516 -25.477 22.706 1.00 248.43 ? 234 ARG G NH2 1 +ATOM 13137 N N . GLY G 1 235 ? 83.624 -20.099 27.399 1.00 102.55 ? 235 GLY G N 1 +ATOM 13138 C CA . GLY G 1 235 ? 84.140 -18.841 27.922 1.00 116.07 ? 235 GLY G CA 1 +ATOM 13139 C C . GLY G 1 235 ? 83.122 -18.119 28.770 1.00 123.65 ? 235 GLY G C 1 +ATOM 13140 O O . GLY G 1 235 ? 83.090 -16.885 28.791 1.00 106.29 ? 235 GLY G O 1 +ATOM 13141 N N . LEU G 1 236 ? 82.264 -18.880 29.451 1.00 143.14 ? 236 LEU G N 1 +ATOM 13142 C CA . LEU G 1 236 ? 81.378 -18.284 30.466 1.00 148.53 ? 236 LEU G CA 1 +ATOM 13143 C C . LEU G 1 236 ? 82.204 -17.958 31.697 1.00 126.20 ? 236 LEU G C 1 +ATOM 13144 O O . LEU G 1 236 ? 82.136 -16.851 32.229 1.00 139.36 ? 236 LEU G O 1 +ATOM 13145 C CB . LEU G 1 236 ? 80.217 -19.220 30.854 1.00 144.74 ? 236 LEU G CB 1 +ATOM 13146 C CG . LEU G 1 236 ? 78.961 -19.222 29.963 1.00 129.40 ? 236 LEU G CG 1 +ATOM 13147 C CD1 . LEU G 1 236 ? 79.193 -20.043 28.702 1.00 143.04 ? 236 LEU G CD1 1 +ATOM 13148 C CD2 . LEU G 1 236 ? 77.774 -19.775 30.729 1.00 114.83 ? 236 LEU G CD2 1 +ATOM 13149 N N . TRP G 1 237 ? 83.004 -18.922 32.124 1.00 114.10 ? 237 TRP G N 1 +ATOM 13150 C CA . TRP G 1 237 ? 83.823 -18.761 33.316 1.00 152.79 ? 237 TRP G CA 1 +ATOM 13151 C C . TRP G 1 237 ? 85.207 -19.377 33.097 1.00 198.59 ? 237 TRP G C 1 +ATOM 13152 O O . TRP G 1 237 ? 85.407 -20.149 32.147 1.00 245.96 ? 237 TRP G O 1 +ATOM 13153 C CB . TRP G 1 237 ? 83.125 -19.390 34.524 1.00 132.47 ? 237 TRP G CB 1 +ATOM 13154 C CG . TRP G 1 237 ? 82.312 -20.583 34.170 1.00 128.80 ? 237 TRP G CG 1 +ATOM 13155 C CD1 . TRP G 1 237 ? 82.778 -21.793 33.749 1.00 149.18 ? 237 TRP G CD1 1 +ATOM 13156 C CD2 . TRP G 1 237 ? 80.888 -20.690 34.194 1.00 142.49 ? 237 TRP G CD2 1 +ATOM 13157 N NE1 . TRP G 1 237 ? 81.733 -22.653 33.521 1.00 142.86 ? 237 TRP G NE1 1 +ATOM 13158 C CE2 . TRP G 1 237 ? 80.560 -22.007 33.800 1.00 142.50 ? 237 TRP G CE2 1 +ATOM 13159 C CE3 . TRP G 1 237 ? 79.856 -19.812 34.533 1.00 148.66 ? 237 TRP G CE3 1 +ATOM 13160 C CZ2 . TRP G 1 237 ? 79.242 -22.460 33.719 1.00 133.67 ? 237 TRP G CZ2 1 +ATOM 13161 C CZ3 . TRP G 1 237 ? 78.546 -20.274 34.468 1.00 144.28 ? 237 TRP G CZ3 1 +ATOM 13162 C CH2 . TRP G 1 237 ? 78.254 -21.581 34.055 1.00 128.12 ? 237 TRP G CH2 1 +ATOM 13163 N N . ASP G 1 238 ? 86.152 -19.037 33.977 1.00 189.01 ? 238 ASP G N 1 +ATOM 13164 C CA . ASP G 1 238 ? 87.548 -19.427 33.799 1.00 152.71 ? 238 ASP G CA 1 +ATOM 13165 C C . ASP G 1 238 ? 88.145 -20.101 35.029 1.00 154.22 ? 238 ASP G C 1 +ATOM 13166 O O . ASP G 1 238 ? 87.815 -19.769 36.168 1.00 126.74 ? 238 ASP G O 1 +ATOM 13167 C CB . ASP G 1 238 ? 88.395 -18.220 33.411 1.00 118.63 ? 238 ASP G CB 1 +ATOM 13168 C CG . ASP G 1 238 ? 87.881 -17.531 32.160 1.00 122.59 ? 238 ASP G CG 1 +ATOM 13169 O OD1 . ASP G 1 238 ? 86.918 -16.753 32.273 1.00 92.03 ? 238 ASP G OD1 1 +ATOM 13170 O OD2 . ASP G 1 238 ? 88.445 -17.745 31.062 1.00 165.75 ? 238 ASP G OD2 1 +ATOM 13171 N N . LEU G 1 239 ? 89.057 -21.031 34.767 1.00 155.97 ? 239 LEU G N 1 +ATOM 13172 C CA . LEU G 1 239 ? 89.710 -21.819 35.796 1.00 152.36 ? 239 LEU G CA 1 +ATOM 13173 C C . LEU G 1 239 ? 90.829 -20.980 36.474 1.00 170.47 ? 239 LEU G C 1 +ATOM 13174 O O . LEU G 1 239 ? 91.454 -20.091 35.854 1.00 173.99 ? 239 LEU G O 1 +ATOM 13175 C CB . LEU G 1 239 ? 90.151 -23.190 35.188 1.00 138.65 ? 239 LEU G CB 1 +ATOM 13176 C CG . LEU G 1 239 ? 89.777 -24.420 36.017 1.00 126.34 ? 239 LEU G CG 1 +ATOM 13177 C CD1 . LEU G 1 239 ? 90.227 -25.698 35.336 1.00 108.69 ? 239 LEU G CD1 1 +ATOM 13178 C CD2 . LEU G 1 239 ? 90.395 -24.333 37.412 1.00 116.86 ? 239 LEU G CD2 1 +ATOM 13179 N N . GLN G 1 240 ? 90.953 -21.132 37.794 1.00 154.97 ? 240 GLN G N 1 +ATOM 13180 C CA . GLN G 1 240 ? 92.051 -20.506 38.537 1.00 152.91 ? 240 GLN G CA 1 +ATOM 13181 C C . GLN G 1 240 ? 93.385 -20.861 37.884 1.00 151.24 ? 240 GLN G C 1 +ATOM 13182 O O . GLN G 1 240 ? 94.166 -19.983 37.509 1.00 148.44 ? 240 GLN G O 1 +ATOM 13183 C CB . GLN G 1 240 ? 92.040 -20.975 40.004 1.00 157.09 ? 240 GLN G CB 1 +ATOM 13184 C CG . GLN G 1 240 ? 93.032 -20.241 40.898 1.00 148.08 ? 240 GLN G CG 1 +ATOM 13185 C CD . GLN G 1 240 ? 92.680 -18.768 41.025 1.00 141.77 ? 240 GLN G CD 1 +ATOM 13186 O OE1 . GLN G 1 240 ? 91.827 -18.392 41.837 1.00 184.74 ? 240 GLN G OE1 1 +ATOM 13187 N NE2 . GLN G 1 240 ? 93.323 -17.925 40.216 1.00 112.64 ? 240 GLN G NE2 1 +ATOM 13188 N N . ASN G 1 241 ? 93.630 -22.162 37.764 1.00 150.54 ? 241 ASN G N 1 +ATOM 13189 C CA . ASN G 1 241 ? 94.844 -22.680 37.150 1.00 144.10 ? 241 ASN G CA 1 +ATOM 13190 C C . ASN G 1 241 ? 94.550 -23.187 35.752 1.00 151.96 ? 241 ASN G C 1 +ATOM 13191 O O . ASN G 1 241 ? 93.907 -24.240 35.586 1.00 178.05 ? 241 ASN G O 1 +ATOM 13192 C CB . ASN G 1 241 ? 95.405 -23.826 37.993 1.00 146.87 ? 241 ASN G CB 1 +ATOM 13193 C CG . ASN G 1 241 ? 96.563 -23.395 38.862 1.00 162.48 ? 241 ASN G CG 1 +ATOM 13194 O OD1 . ASN G 1 241 ? 97.717 -23.651 38.528 1.00 155.73 ? 241 ASN G OD1 1 +ATOM 13195 N ND2 . ASN G 1 241 ? 96.267 -22.706 39.967 1.00 178.11 ? 241 ASN G ND2 1 +ATOM 13196 N N . LYS G 1 242 ? 95.060 -22.472 34.753 1.00 135.07 ? 242 LYS G N 1 +ATOM 13197 C CA . LYS G 1 242 ? 94.880 -22.882 33.365 1.00 143.74 ? 242 LYS G CA 1 +ATOM 13198 C C . LYS G 1 242 ? 95.586 -24.220 33.105 1.00 169.66 ? 242 LYS G C 1 +ATOM 13199 O O . LYS G 1 242 ? 95.175 -24.999 32.233 1.00 132.14 ? 242 LYS G O 1 +ATOM 13200 C CB . LYS G 1 242 ? 95.399 -21.799 32.419 1.00 135.35 ? 242 LYS G CB 1 +ATOM 13201 C CG . LYS G 1 242 ? 94.911 -20.400 32.764 1.00 132.87 ? 242 LYS G CG 1 +ATOM 13202 C CD . LYS G 1 242 ? 94.243 -19.724 31.579 1.00 149.36 ? 242 LYS G CD 1 +ATOM 13203 C CE . LYS G 1 242 ? 92.929 -19.076 31.991 1.00 164.84 ? 242 LYS G CE 1 +ATOM 13204 N NZ . LYS G 1 242 ? 92.321 -18.269 30.898 1.00 173.16 ? 242 LYS G NZ 1 +ATOM 13205 N N . ALA G 1 243 ? 96.618 -24.484 33.912 1.00 202.86 ? 243 ALA G N 1 +ATOM 13206 C CA . ALA G 1 243 ? 97.339 -25.759 33.924 1.00 190.66 ? 243 ALA G CA 1 +ATOM 13207 C C . ALA G 1 243 ? 96.429 -26.926 34.315 1.00 195.18 ? 243 ALA G C 1 +ATOM 13208 O O . ALA G 1 243 ? 96.759 -28.084 34.046 1.00 208.32 ? 243 ALA G O 1 +ATOM 13209 C CB . ALA G 1 243 ? 98.522 -25.685 34.886 1.00 157.47 ? 243 ALA G CB 1 +ATOM 13210 N N . GLU G 1 244 ? 95.297 -26.624 34.956 1.00 165.69 ? 244 GLU G N 1 +ATOM 13211 C CA . GLU G 1 244 ? 94.390 -27.669 35.414 1.00 142.69 ? 244 GLU G CA 1 +ATOM 13212 C C . GLU G 1 244 ? 93.294 -27.959 34.401 1.00 146.07 ? 244 GLU G C 1 +ATOM 13213 O O . GLU G 1 244 ? 92.371 -28.700 34.709 1.00 129.17 ? 244 GLU G O 1 +ATOM 13214 C CB . GLU G 1 244 ? 93.757 -27.297 36.754 1.00 139.01 ? 244 GLU G CB 1 +ATOM 13215 C CG . GLU G 1 244 ? 94.708 -27.382 37.933 1.00 154.81 ? 244 GLU G CG 1 +ATOM 13216 C CD . GLU G 1 244 ? 94.004 -27.264 39.274 1.00 153.20 ? 244 GLU G CD 1 +ATOM 13217 O OE1 . GLU G 1 244 ? 93.628 -26.140 39.658 1.00 136.38 ? 244 GLU G OE1 1 +ATOM 13218 O OE2 . GLU G 1 244 ? 93.822 -28.304 39.944 1.00 144.87 ? 244 GLU G OE2 1 +ATOM 13219 N N . ARG G 1 245 ? 93.427 -27.437 33.180 1.00 137.12 ? 245 ARG G N 1 +ATOM 13220 C CA . ARG G 1 245 ? 92.520 -27.808 32.092 1.00 142.17 ? 245 ARG G CA 1 +ATOM 13221 C C . ARG G 1 245 ? 92.455 -29.315 31.832 1.00 159.74 ? 245 ARG G C 1 +ATOM 13222 O O . ARG G 1 245 ? 91.390 -29.837 31.505 1.00 154.55 ? 245 ARG G O 1 +ATOM 13223 C CB . ARG G 1 245 ? 92.878 -27.107 30.790 1.00 137.94 ? 245 ARG G CB 1 +ATOM 13224 C CG . ARG G 1 245 ? 91.828 -27.294 29.691 1.00 141.37 ? 245 ARG G CG 1 +ATOM 13225 C CD . ARG G 1 245 ? 92.137 -26.488 28.413 1.00 158.50 ? 245 ARG G CD 1 +ATOM 13226 N NE . ARG G 1 245 ? 91.399 -25.220 28.366 1.00 173.44 ? 245 ARG G NE 1 +ATOM 13227 C CZ . ARG G 1 245 ? 90.084 -25.111 28.160 1.00 171.01 ? 245 ARG G CZ 1 +ATOM 13228 N NH1 . ARG G 1 245 ? 89.337 -26.192 27.997 1.00 154.53 ? 245 ARG G NH1 1 +ATOM 13229 N NH2 . ARG G 1 245 ? 89.502 -23.918 28.141 1.00 159.07 ? 245 ARG G NH2 1 +ATOM 13230 N N . GLN G 1 246 ? 93.591 -30.003 31.944 1.00 166.93 ? 246 GLN G N 1 +ATOM 13231 C CA . GLN G 1 246 ? 93.642 -31.435 31.636 1.00 151.12 ? 246 GLN G CA 1 +ATOM 13232 C C . GLN G 1 246 ? 93.397 -32.288 32.875 1.00 135.48 ? 246 GLN G C 1 +ATOM 13233 O O . GLN G 1 246 ? 93.809 -33.445 32.931 1.00 156.00 ? 246 GLN G O 1 +ATOM 13234 C CB . GLN G 1 246 ? 94.976 -31.807 30.972 1.00 153.70 ? 246 GLN G CB 1 +ATOM 13235 C CG . GLN G 1 246 ? 95.138 -31.297 29.547 1.00 152.04 ? 246 GLN G CG 1 +ATOM 13236 C CD . GLN G 1 246 ? 95.435 -29.814 29.502 1.00 166.22 ? 246 GLN G CD 1 +ATOM 13237 O OE1 . GLN G 1 246 ? 96.281 -29.313 30.255 1.00 165.90 ? 246 GLN G OE1 1 +ATOM 13238 N NE2 . GLN G 1 246 ? 94.769 -29.104 28.597 1.00 171.38 ? 246 GLN G NE2 1 +ATOM 13239 N N . ASN G 1 247 ? 92.767 -31.690 33.883 1.00 128.54 ? 247 ASN G N 1 +ATOM 13240 C CA . ASN G 1 247 ? 92.268 -32.418 35.053 1.00 154.43 ? 247 ASN G CA 1 +ATOM 13241 C C . ASN G 1 247 ? 91.603 -33.737 34.648 1.00 169.30 ? 247 ASN G C 1 +ATOM 13242 O O . ASN G 1 247 ? 90.861 -33.777 33.661 1.00 172.15 ? 247 ASN G O 1 +ATOM 13243 C CB . ASN G 1 247 ? 91.248 -31.540 35.783 1.00 153.87 ? 247 ASN G CB 1 +ATOM 13244 C CG . ASN G 1 247 ? 91.120 -31.878 37.246 1.00 155.64 ? 247 ASN G CG 1 +ATOM 13245 O OD1 . ASN G 1 247 ? 90.116 -32.454 37.680 1.00 165.16 ? 247 ASN G OD1 1 +ATOM 13246 N ND2 . ASN G 1 247 ? 92.142 -31.530 38.015 1.00 149.18 ? 247 ASN G ND2 1 +ATOM 13247 N N . ASP G 1 248 ? 91.857 -34.801 35.416 1.00 178.38 ? 248 ASP G N 1 +ATOM 13248 C CA . ASP G 1 248 ? 91.325 -36.143 35.106 1.00 207.99 ? 248 ASP G CA 1 +ATOM 13249 C C . ASP G 1 248 ? 89.807 -36.118 34.896 1.00 231.30 ? 248 ASP G C 1 +ATOM 13250 O O . ASP G 1 248 ? 89.273 -36.698 33.937 1.00 268.75 ? 248 ASP G O 1 +ATOM 13251 C CB . ASP G 1 248 ? 91.635 -37.130 36.243 1.00 180.83 ? 248 ASP G CB 1 +ATOM 13252 C CG . ASP G 1 248 ? 93.101 -37.501 36.325 1.00 162.50 ? 248 ASP G CG 1 +ATOM 13253 O OD1 . ASP G 1 248 ? 93.749 -37.661 35.266 1.00 175.11 ? 248 ASP G OD1 1 +ATOM 13254 O OD2 . ASP G 1 248 ? 93.597 -37.660 37.456 1.00 128.14 ? 248 ASP G OD2 1 +ATOM 13255 N N . ILE G 1 249 ? 89.122 -35.450 35.818 1.00 213.31 ? 249 ILE G N 1 +ATOM 13256 C CA . ILE G 1 249 ? 87.671 -35.387 35.809 1.00 183.10 ? 249 ILE G CA 1 +ATOM 13257 C C . ILE G 1 249 ? 87.190 -34.606 34.579 1.00 180.30 ? 249 ILE G C 1 +ATOM 13258 O O . ILE G 1 249 ? 86.327 -35.072 33.821 1.00 216.42 ? 249 ILE G O 1 +ATOM 13259 C CB . ILE G 1 249 ? 87.152 -34.730 37.107 1.00 144.02 ? 249 ILE G CB 1 +ATOM 13260 C CG1 . ILE G 1 249 ? 87.539 -35.574 38.324 1.00 134.74 ? 249 ILE G CG1 1 +ATOM 13261 C CG2 . ILE G 1 249 ? 85.646 -34.585 37.058 1.00 135.39 ? 249 ILE G CG2 1 +ATOM 13262 C CD1 . ILE G 1 249 ? 87.521 -34.817 39.634 1.00 136.54 ? 249 ILE G CD1 1 +ATOM 13263 N N . LEU G 1 250 ? 87.768 -33.425 34.374 1.00 142.23 ? 250 LEU G N 1 +ATOM 13264 C CA . LEU G 1 250 ? 87.372 -32.556 33.266 1.00 152.22 ? 250 LEU G CA 1 +ATOM 13265 C C . LEU G 1 250 ? 87.559 -33.208 31.894 1.00 158.93 ? 250 LEU G C 1 +ATOM 13266 O O . LEU G 1 250 ? 86.728 -33.022 31.001 1.00 176.66 ? 250 LEU G O 1 +ATOM 13267 C CB . LEU G 1 250 ? 88.146 -31.240 33.314 1.00 153.05 ? 250 LEU G CB 1 +ATOM 13268 C CG . LEU G 1 250 ? 87.615 -30.213 34.317 1.00 166.21 ? 250 LEU G CG 1 +ATOM 13269 C CD1 . LEU G 1 250 ? 88.596 -29.067 34.515 1.00 188.30 ? 250 LEU G CD1 1 +ATOM 13270 C CD2 . LEU G 1 250 ? 86.270 -29.673 33.859 1.00 175.26 ? 250 LEU G CD2 1 +ATOM 13271 N N . VAL G 1 251 ? 88.644 -33.964 31.732 1.00 164.53 ? 251 VAL G N 1 +ATOM 13272 C CA . VAL G 1 251 ? 88.898 -34.669 30.469 1.00 153.83 ? 251 VAL G CA 1 +ATOM 13273 C C . VAL G 1 251 ? 88.017 -35.912 30.325 1.00 155.98 ? 251 VAL G C 1 +ATOM 13274 O O . VAL G 1 251 ? 87.738 -36.359 29.210 1.00 126.16 ? 251 VAL G O 1 +ATOM 13275 C CB . VAL G 1 251 ? 90.382 -35.066 30.305 1.00 132.09 ? 251 VAL G CB 1 +ATOM 13276 C CG1 . VAL G 1 251 ? 91.274 -33.841 30.452 1.00 112.49 ? 251 VAL G CG1 1 +ATOM 13277 C CG2 . VAL G 1 251 ? 90.778 -36.165 31.288 1.00 124.81 ? 251 VAL G CG2 1 +ATOM 13278 N N . LYS G 1 252 ? 87.577 -36.461 31.456 1.00 152.60 ? 252 LYS G N 1 +ATOM 13279 C CA . LYS G 1 252 ? 86.657 -37.593 31.453 1.00 138.30 ? 252 LYS G CA 1 +ATOM 13280 C C . LYS G 1 252 ? 85.287 -37.167 30.897 1.00 159.99 ? 252 LYS G C 1 +ATOM 13281 O O . LYS G 1 252 ? 84.722 -37.830 30.013 1.00 142.01 ? 252 LYS G O 1 +ATOM 13282 C CB . LYS G 1 252 ? 86.541 -38.150 32.876 1.00 111.91 ? 252 LYS G CB 1 +ATOM 13283 C CG . LYS G 1 252 ? 85.588 -39.318 33.039 1.00 115.68 ? 252 LYS G CG 1 +ATOM 13284 C CD . LYS G 1 252 ? 85.547 -39.764 34.496 1.00 108.19 ? 252 LYS G CD 1 +ATOM 13285 C CE . LYS G 1 252 ? 84.119 -39.958 34.982 1.00 118.12 ? 252 LYS G CE 1 +ATOM 13286 N NZ . LYS G 1 252 ? 84.035 -40.140 36.457 1.00 119.43 ? 252 LYS G NZ 1 +ATOM 13287 N N . TYR G 1 253 ? 84.785 -36.028 31.375 1.00 174.66 ? 253 TYR G N 1 +ATOM 13288 C CA . TYR G 1 253 ? 83.477 -35.502 30.938 1.00 149.38 ? 253 TYR G CA 1 +ATOM 13289 C C . TYR G 1 253 ? 83.573 -34.840 29.573 1.00 150.83 ? 253 TYR G C 1 +ATOM 13290 O O . TYR G 1 253 ? 82.623 -34.885 28.786 1.00 166.64 ? 253 TYR G O 1 +ATOM 13291 C CB . TYR G 1 253 ? 82.906 -34.528 31.971 1.00 118.71 ? 253 TYR G CB 1 +ATOM 13292 C CG . TYR G 1 253 ? 82.437 -35.250 33.223 1.00 136.04 ? 253 TYR G CG 1 +ATOM 13293 C CD1 . TYR G 1 253 ? 81.183 -35.853 33.281 1.00 119.66 ? 253 TYR G CD1 1 +ATOM 13294 C CD2 . TYR G 1 253 ? 83.294 -35.424 34.315 1.00 158.59 ? 253 TYR G CD2 1 +ATOM 13295 C CE1 . TYR G 1 253 ? 80.782 -36.546 34.413 1.00 110.99 ? 253 TYR G CE1 1 +ATOM 13296 C CE2 . TYR G 1 253 ? 82.895 -36.128 35.449 1.00 126.14 ? 253 TYR G CE2 1 +ATOM 13297 C CZ . TYR G 1 253 ? 81.629 -36.668 35.495 1.00 104.54 ? 253 TYR G CZ 1 +ATOM 13298 O OH . TYR G 1 253 ? 81.212 -37.329 36.637 1.00 103.86 ? 253 TYR G OH 1 +ATOM 13299 N N . ARG G 1 254 ? 84.735 -34.256 29.285 1.00 140.14 ? 254 ARG G N 1 +ATOM 13300 C CA . ARG G 1 254 ? 85.048 -33.781 27.933 1.00 120.54 ? 254 ARG G CA 1 +ATOM 13301 C C . ARG G 1 254 ? 84.968 -34.930 26.932 1.00 118.09 ? 254 ARG G C 1 +ATOM 13302 O O . ARG G 1 254 ? 84.455 -34.768 25.822 1.00 96.90 ? 254 ARG G O 1 +ATOM 13303 C CB . ARG G 1 254 ? 86.448 -33.168 27.888 1.00 128.89 ? 254 ARG G CB 1 +ATOM 13304 C CG . ARG G 1 254 ? 86.781 -32.546 26.546 1.00 138.56 ? 254 ARG G CG 1 +ATOM 13305 C CD . ARG G 1 254 ? 87.964 -31.596 26.623 1.00 163.62 ? 254 ARG G CD 1 +ATOM 13306 N NE . ARG G 1 254 ? 87.700 -30.405 27.429 1.00 161.82 ? 254 ARG G NE 1 +ATOM 13307 C CZ . ARG G 1 254 ? 88.227 -30.156 28.624 1.00 168.18 ? 254 ARG G CZ 1 +ATOM 13308 N NH1 . ARG G 1 254 ? 89.043 -31.026 29.207 1.00 163.68 ? 254 ARG G NH1 1 +ATOM 13309 N NH2 . ARG G 1 254 ? 87.925 -29.024 29.246 1.00 167.37 ? 254 ARG G NH2 1 +ATOM 13310 N N . HIS G 1 255 ? 85.454 -36.103 27.352 1.00 141.74 ? 255 HIS G N 1 +ATOM 13311 C CA . HIS G 1 255 ? 85.444 -37.303 26.508 1.00 151.60 ? 255 HIS G CA 1 +ATOM 13312 C C . HIS G 1 255 ? 84.041 -37.836 26.260 1.00 135.16 ? 255 HIS G C 1 +ATOM 13313 O O . HIS G 1 255 ? 83.750 -38.351 25.184 1.00 109.06 ? 255 HIS G O 1 +ATOM 13314 C CB . HIS G 1 255 ? 86.343 -38.405 27.102 1.00 167.17 ? 255 HIS G CB 1 +ATOM 13315 C CG . HIS G 1 255 ? 87.629 -38.592 26.359 1.00 183.13 ? 255 HIS G CG 1 +ATOM 13316 N ND1 . HIS G 1 255 ? 88.675 -37.698 26.451 1.00 202.52 ? 255 HIS G ND1 1 +ATOM 13317 C CD2 . HIS G 1 255 ? 88.017 -39.539 25.472 1.00 162.88 ? 255 HIS G CD2 1 +ATOM 13318 C CE1 . HIS G 1 255 ? 89.660 -38.098 25.665 1.00 196.10 ? 255 HIS G CE1 1 +ATOM 13319 N NE2 . HIS G 1 255 ? 89.286 -39.213 25.062 1.00 174.59 ? 255 HIS G NE2 1 +ATOM 13320 N N . MET G 1 256 ? 83.174 -37.732 27.262 1.00 148.54 ? 256 MET G N 1 +ATOM 13321 C CA . MET G 1 256 ? 81.803 -38.215 27.104 1.00 136.52 ? 256 MET G CA 1 +ATOM 13322 C C . MET G 1 256 ? 81.037 -37.379 26.064 1.00 137.48 ? 256 MET G C 1 +ATOM 13323 O O . MET G 1 256 ? 80.066 -37.872 25.471 1.00 136.21 ? 256 MET G O 1 +ATOM 13324 C CB . MET G 1 256 ? 81.092 -38.268 28.466 1.00 137.66 ? 256 MET G CB 1 +ATOM 13325 C CG . MET G 1 256 ? 81.862 -39.063 29.526 1.00 145.85 ? 256 MET G CG 1 +ATOM 13326 S SD . MET G 1 256 ? 80.904 -39.626 30.941 1.00 173.89 ? 256 MET G SD 1 +ATOM 13327 C CE . MET G 1 256 ? 79.849 -40.857 30.158 1.00 170.98 ? 256 MET G CE 1 +ATOM 13328 N N . SER G 1 257 ? 81.493 -36.137 25.837 1.00 142.61 ? 257 SER G N 1 +ATOM 13329 C CA . SER G 1 257 ? 80.922 -35.235 24.807 1.00 122.25 ? 257 SER G CA 1 +ATOM 13330 C C . SER G 1 257 ? 81.422 -35.560 23.411 1.00 99.62 ? 257 SER G C 1 +ATOM 13331 O O . SER G 1 257 ? 80.880 -36.461 22.772 1.00 119.70 ? 257 SER G O 1 +ATOM 13332 C CB . SER G 1 257 ? 81.246 -33.774 25.122 1.00 100.52 ? 257 SER G CB 1 +ATOM 13333 O OG . SER G 1 257 ? 81.092 -33.501 26.521 1.00 121.49 ? 257 SER G OG 1 +ATOM 13334 N N . LEU H 1 2 ? 74.701 -54.538 56.152 1.00 111.27 ? 2 LEU H N 1 +ATOM 13335 C CA . LEU H 1 2 ? 73.849 -54.413 54.919 1.00 120.07 ? 2 LEU H CA 1 +ATOM 13336 C C . LEU H 1 2 ? 72.368 -54.189 55.305 1.00 134.62 ? 2 LEU H C 1 +ATOM 13337 O O . LEU H 1 2 ? 71.495 -55.073 55.131 1.00 94.67 ? 2 LEU H O 1 +ATOM 13338 C CB . LEU H 1 2 ? 74.013 -55.633 53.994 1.00 122.39 ? 2 LEU H CB 1 +ATOM 13339 C CG . LEU H 1 2 ? 75.408 -55.936 53.394 1.00 115.06 ? 2 LEU H CG 1 +ATOM 13340 C CD1 . LEU H 1 2 ? 75.326 -57.205 52.549 1.00 109.36 ? 2 LEU H CD1 1 +ATOM 13341 C CD2 . LEU H 1 2 ? 76.025 -54.786 52.584 1.00 86.95 ? 2 LEU H CD2 1 +ATOM 13342 N N . THR H 1 3 ? 72.153 -53.048 55.970 1.00 177.19 ? 3 THR H N 1 +ATOM 13343 C CA . THR H 1 3 ? 70.832 -52.412 56.118 1.00 167.04 ? 3 THR H CA 1 +ATOM 13344 C C . THR H 1 3 ? 70.951 -50.882 55.950 1.00 120.40 ? 3 THR H C 1 +ATOM 13345 O O . THR H 1 3 ? 69.960 -50.167 55.968 1.00 88.43 ? 3 THR H O 1 +ATOM 13346 C CB . THR H 1 3 ? 70.191 -52.703 57.490 1.00 165.82 ? 3 THR H CB 1 +ATOM 13347 O OG1 . THR H 1 3 ? 70.927 -52.026 58.518 1.00 179.84 ? 3 THR H OG1 1 +ATOM 13348 C CG2 . THR H 1 3 ? 70.129 -54.217 57.760 1.00 151.21 ? 3 THR H CG2 1 +ATOM 13349 N N . ALA H 1 4 ? 72.178 -50.397 55.805 1.00 98.80 ? 4 ALA H N 1 +ATOM 13350 C CA . ALA H 1 4 ? 72.428 -49.133 55.132 1.00 112.42 ? 4 ALA H CA 1 +ATOM 13351 C C . ALA H 1 4 ? 72.230 -49.320 53.606 1.00 114.30 ? 4 ALA H C 1 +ATOM 13352 O O . ALA H 1 4 ? 71.786 -50.367 53.157 1.00 75.49 ? 4 ALA H O 1 +ATOM 13353 C CB . ALA H 1 4 ? 73.832 -48.632 55.451 1.00 130.07 ? 4 ALA H CB 1 +ATOM 13354 N N . PRO H 1 5 ? 72.461 -48.272 52.802 1.00 154.99 ? 5 PRO H N 1 +ATOM 13355 C CA . PRO H 1 5 ? 71.868 -48.441 51.479 1.00 157.27 ? 5 PRO H CA 1 +ATOM 13356 C C . PRO H 1 5 ? 72.752 -49.279 50.556 1.00 158.86 ? 5 PRO H C 1 +ATOM 13357 O O . PRO H 1 5 ? 73.900 -49.566 50.895 1.00 83.16 ? 5 PRO H O 1 +ATOM 13358 C CB . PRO H 1 5 ? 71.747 -47.002 50.973 1.00 172.72 ? 5 PRO H CB 1 +ATOM 13359 C CG . PRO H 1 5 ? 72.821 -46.229 51.691 1.00 185.33 ? 5 PRO H CG 1 +ATOM 13360 C CD . PRO H 1 5 ? 73.191 -46.994 52.936 1.00 172.46 ? 5 PRO H CD 1 +ATOM 13361 N N . PRO H 1 6 ? 72.222 -49.655 49.384 1.00 165.20 ? 6 PRO H N 1 +ATOM 13362 C CA . PRO H 1 6 ? 73.049 -50.168 48.283 1.00 148.65 ? 6 PRO H CA 1 +ATOM 13363 C C . PRO H 1 6 ? 73.732 -49.064 47.479 1.00 132.21 ? 6 PRO H C 1 +ATOM 13364 O O . PRO H 1 6 ? 73.217 -47.958 47.397 1.00 141.52 ? 6 PRO H O 1 +ATOM 13365 C CB . PRO H 1 6 ? 72.054 -50.934 47.414 1.00 155.84 ? 6 PRO H CB 1 +ATOM 13366 C CG . PRO H 1 6 ? 70.698 -50.449 47.797 1.00 156.29 ? 6 PRO H CG 1 +ATOM 13367 C CD . PRO H 1 6 ? 70.775 -49.766 49.129 1.00 142.59 ? 6 PRO H CD 1 +ATOM 13368 N N . LYS H 1 7 ? 74.891 -49.355 46.900 1.00 129.34 ? 7 LYS H N 1 +ATOM 13369 C CA . LYS H 1 7 ? 75.616 -48.354 46.090 1.00 142.44 ? 7 LYS H CA 1 +ATOM 13370 C C . LYS H 1 7 ? 75.307 -48.492 44.582 1.00 140.17 ? 7 LYS H C 1 +ATOM 13371 O O . LYS H 1 7 ? 74.673 -49.468 44.149 1.00 115.61 ? 7 LYS H O 1 +ATOM 13372 C CB . LYS H 1 7 ? 77.126 -48.424 46.343 1.00 138.58 ? 7 LYS H CB 1 +ATOM 13373 C CG . LYS H 1 7 ? 77.544 -47.727 47.645 1.00 136.38 ? 7 LYS H CG 1 +ATOM 13374 C CD . LYS H 1 7 ? 77.675 -46.276 47.243 1.00 133.93 ? 7 LYS H CD 1 +ATOM 13375 C CE . LYS H 1 7 ? 76.654 -45.365 47.869 1.00 142.02 ? 7 LYS H CE 1 +ATOM 13376 N NZ . LYS H 1 7 ? 77.006 -43.917 47.661 1.00 134.30 ? 7 LYS H NZ 1 +ATOM 13377 N N . GLU H 1 8 ? 75.729 -47.485 43.809 1.00 129.53 ? 8 GLU H N 1 +ATOM 13378 C CA . GLU H 1 8 ? 75.238 -47.279 42.442 1.00 154.03 ? 8 GLU H CA 1 +ATOM 13379 C C . GLU H 1 8 ? 75.685 -48.385 41.492 1.00 145.66 ? 8 GLU H C 1 +ATOM 13380 O O . GLU H 1 8 ? 76.865 -48.582 41.276 1.00 177.47 ? 8 GLU H O 1 +ATOM 13381 C CB . GLU H 1 8 ? 75.635 -45.875 41.880 1.00 177.46 ? 8 GLU H CB 1 +ATOM 13382 C CG . GLU H 1 8 ? 77.026 -45.695 41.308 1.00 197.90 ? 8 GLU H CG 1 +ATOM 13383 C CD . GLU H 1 8 ? 77.204 -44.364 40.574 1.00 205.77 ? 8 GLU H CD 1 +ATOM 13384 O OE1 . GLU H 1 8 ? 76.425 -44.070 39.634 1.00 188.96 ? 8 GLU H OE1 1 +ATOM 13385 O OE2 . GLU H 1 8 ? 78.151 -43.619 40.916 1.00 203.59 ? 8 GLU H OE2 1 +ATOM 13386 N N . ALA H 1 9 ? 74.717 -49.116 40.953 1.00 128.59 ? 9 ALA H N 1 +ATOM 13387 C CA . ALA H 1 9 ? 74.952 -50.081 39.894 1.00 102.25 ? 9 ALA H CA 1 +ATOM 13388 C C . ALA H 1 9 ? 74.671 -49.433 38.523 1.00 102.77 ? 9 ALA H C 1 +ATOM 13389 O O . ALA H 1 9 ? 73.523 -49.099 38.207 1.00 95.37 ? 9 ALA H O 1 +ATOM 13390 C CB . ALA H 1 9 ? 74.058 -51.287 40.112 1.00 85.42 ? 9 ALA H CB 1 +ATOM 13391 N N . ALA H 1 10 ? 75.732 -49.244 37.744 1.00 82.19 ? 10 ALA H N 1 +ATOM 13392 C CA . ALA H 1 10 ? 75.714 -48.482 36.489 1.00 88.84 ? 10 ALA H CA 1 +ATOM 13393 C C . ALA H 1 10 ? 75.951 -47.001 36.762 1.00 95.98 ? 10 ALA H C 1 +ATOM 13394 O O . ALA H 1 10 ? 75.680 -46.519 37.855 1.00 70.53 ? 10 ALA H O 1 +ATOM 13395 C CB . ALA H 1 10 ? 74.438 -48.722 35.666 1.00 67.33 ? 10 ALA H CB 1 +ATOM 13396 N N . ARG H 1 11 ? 76.458 -46.305 35.740 1.00 117.65 ? 11 ARG H N 1 +ATOM 13397 C CA . ARG H 1 11 ? 76.868 -44.909 35.886 1.00 123.95 ? 11 ARG H CA 1 +ATOM 13398 C C . ARG H 1 11 ? 75.950 -43.921 35.121 1.00 83.30 ? 11 ARG H C 1 +ATOM 13399 O O . ARG H 1 11 ? 75.334 -44.257 34.095 1.00 108.49 ? 11 ARG H O 1 +ATOM 13400 C CB . ARG H 1 11 ? 78.366 -44.755 35.598 1.00 144.22 ? 11 ARG H CB 1 +ATOM 13401 C CG . ARG H 1 11 ? 79.227 -45.228 36.788 1.00 152.60 ? 11 ARG H CG 1 +ATOM 13402 C CD . ARG H 1 11 ? 80.252 -46.272 36.417 1.00 160.74 ? 11 ARG H CD 1 +ATOM 13403 N NE . ARG H 1 11 ? 80.655 -47.131 37.542 1.00 156.14 ? 11 ARG H NE 1 +ATOM 13404 C CZ . ARG H 1 11 ? 81.358 -48.255 37.407 1.00 148.94 ? 11 ARG H CZ 1 +ATOM 13405 N NH1 . ARG H 1 11 ? 81.768 -48.645 36.206 1.00 132.44 ? 11 ARG H NH1 1 +ATOM 13406 N NH2 . ARG H 1 11 ? 81.658 -48.990 38.471 1.00 140.04 ? 11 ARG H NH2 1 +ATOM 13407 N N . PRO H 1 12 ? 75.811 -42.702 35.636 1.00 56.84 ? 12 PRO H N 1 +ATOM 13408 C CA . PRO H 1 12 ? 75.240 -41.673 34.792 1.00 69.87 ? 12 PRO H CA 1 +ATOM 13409 C C . PRO H 1 12 ? 76.035 -41.415 33.493 1.00 79.36 ? 12 PRO H C 1 +ATOM 13410 O O . PRO H 1 12 ? 77.146 -40.908 33.536 1.00 86.04 ? 12 PRO H O 1 +ATOM 13411 C CB . PRO H 1 12 ? 75.242 -40.405 35.694 1.00 63.84 ? 12 PRO H CB 1 +ATOM 13412 C CG . PRO H 1 12 ? 75.589 -40.883 37.048 1.00 64.73 ? 12 PRO H CG 1 +ATOM 13413 C CD . PRO H 1 12 ? 76.397 -42.130 36.846 1.00 66.88 ? 12 PRO H CD 1 +ATOM 13414 N N . THR H 1 13 ? 75.416 -41.712 32.355 1.00 97.30 ? 13 THR H N 1 +ATOM 13415 C CA . THR H 1 13 ? 75.861 -41.221 31.057 1.00 113.28 ? 13 THR H CA 1 +ATOM 13416 C C . THR H 1 13 ? 75.076 -39.975 30.625 1.00 106.47 ? 13 THR H C 1 +ATOM 13417 O O . THR H 1 13 ? 73.973 -39.741 31.128 1.00 198.84 ? 13 THR H O 1 +ATOM 13418 C CB . THR H 1 13 ? 75.663 -42.322 30.011 1.00 134.24 ? 13 THR H CB 1 +ATOM 13419 O OG1 . THR H 1 13 ? 76.318 -41.940 28.795 1.00 165.30 ? 13 THR H OG1 1 +ATOM 13420 C CG2 . THR H 1 13 ? 74.141 -42.615 29.754 1.00 116.95 ? 13 THR H CG2 1 +ATOM 13421 N N . LEU H 1 14 ? 75.578 -39.196 29.673 1.00 85.31 ? 14 LEU H N 1 +ATOM 13422 C CA . LEU H 1 14 ? 74.694 -38.184 29.057 1.00 123.45 ? 14 LEU H CA 1 +ATOM 13423 C C . LEU H 1 14 ? 73.713 -38.880 28.086 1.00 138.03 ? 14 LEU H C 1 +ATOM 13424 O O . LEU H 1 14 ? 73.916 -40.032 27.756 1.00 129.17 ? 14 LEU H O 1 +ATOM 13425 C CB . LEU H 1 14 ? 75.447 -37.022 28.415 1.00 114.87 ? 14 LEU H CB 1 +ATOM 13426 C CG . LEU H 1 14 ? 76.507 -37.351 27.399 1.00 122.83 ? 14 LEU H CG 1 +ATOM 13427 C CD1 . LEU H 1 14 ? 76.576 -36.261 26.346 1.00 114.22 ? 14 LEU H CD1 1 +ATOM 13428 C CD2 . LEU H 1 14 ? 77.837 -37.467 28.111 1.00 138.63 ? 14 LEU H CD2 1 +ATOM 13429 N N . MET H 1 15 ? 72.578 -38.256 27.766 1.00 151.99 ? 15 MET H N 1 +ATOM 13430 C CA . MET H 1 15 ? 71.374 -39.023 27.375 1.00 129.96 ? 15 MET H CA 1 +ATOM 13431 C C . MET H 1 15 ? 71.560 -39.665 26.000 1.00 109.22 ? 15 MET H C 1 +ATOM 13432 O O . MET H 1 15 ? 71.860 -38.974 25.037 1.00 64.96 ? 15 MET H O 1 +ATOM 13433 C CB . MET H 1 15 ? 70.098 -38.152 27.389 1.00 125.31 ? 15 MET H CB 1 +ATOM 13434 C CG . MET H 1 15 ? 68.819 -38.944 27.676 1.00 113.91 ? 15 MET H CG 1 +ATOM 13435 S SD . MET H 1 15 ? 67.255 -38.446 26.923 1.00 111.27 ? 15 MET H SD 1 +ATOM 13436 C CE . MET H 1 15 ? 67.715 -37.512 25.445 1.00 102.97 ? 15 MET H CE 1 +ATOM 13437 N N . PRO H 1 16 ? 71.407 -41.008 25.930 1.00 109.31 ? 16 PRO H N 1 +ATOM 13438 C CA . PRO H 1 16 ? 71.727 -41.840 24.755 1.00 98.21 ? 16 PRO H CA 1 +ATOM 13439 C C . PRO H 1 16 ? 70.922 -41.570 23.487 1.00 82.63 ? 16 PRO H C 1 +ATOM 13440 O O . PRO H 1 16 ? 69.926 -42.249 23.198 1.00 87.09 ? 16 PRO H O 1 +ATOM 13441 C CB . PRO H 1 16 ? 71.470 -43.268 25.259 1.00 112.92 ? 16 PRO H CB 1 +ATOM 13442 C CG . PRO H 1 16 ? 70.509 -43.109 26.383 1.00 112.35 ? 16 PRO H CG 1 +ATOM 13443 C CD . PRO H 1 16 ? 70.910 -41.834 27.052 1.00 106.71 ? 16 PRO H CD 1 +ATOM 13444 N N . ARG H 1 17 ? 71.295 -40.511 22.789 1.00 90.00 ? 17 ARG H N 1 +ATOM 13445 C CA . ARG H 1 17 ? 70.666 -40.181 21.523 1.00 123.13 ? 17 ARG H CA 1 +ATOM 13446 C C . ARG H 1 17 ? 71.385 -40.967 20.425 1.00 105.68 ? 17 ARG H C 1 +ATOM 13447 O O . ARG H 1 17 ? 72.585 -41.128 20.502 1.00 91.70 ? 17 ARG H O 1 +ATOM 13448 C CB . ARG H 1 17 ? 70.723 -38.650 21.289 1.00 138.90 ? 17 ARG H CB 1 +ATOM 13449 C CG . ARG H 1 17 ? 69.544 -37.883 21.892 1.00 117.05 ? 17 ARG H CG 1 +ATOM 13450 C CD . ARG H 1 17 ? 69.807 -36.401 22.028 1.00 115.87 ? 17 ARG H CD 1 +ATOM 13451 N NE . ARG H 1 17 ? 70.641 -36.095 23.180 1.00 115.93 ? 17 ARG H NE 1 +ATOM 13452 C CZ . ARG H 1 17 ? 71.151 -34.889 23.425 1.00 127.44 ? 17 ARG H CZ 1 +ATOM 13453 N NH1 . ARG H 1 17 ? 70.888 -33.870 22.602 1.00 110.24 ? 17 ARG H NH1 1 +ATOM 13454 N NH2 . ARG H 1 17 ? 71.918 -34.688 24.487 1.00 122.61 ? 17 ARG H NH2 1 +ATOM 13455 N N . ALA H 1 18 ? 70.667 -41.374 19.378 1.00 117.28 ? 18 ALA H N 1 +ATOM 13456 C CA . ALA H 1 18 ? 71.273 -42.138 18.292 1.00 103.03 ? 18 ALA H CA 1 +ATOM 13457 C C . ALA H 1 18 ? 71.305 -41.365 16.957 1.00 94.25 ? 18 ALA H C 1 +ATOM 13458 O O . ALA H 1 18 ? 72.011 -40.348 16.836 1.00 75.51 ? 18 ALA H O 1 +ATOM 13459 C CB . ALA H 1 18 ? 70.573 -43.475 18.137 1.00 93.45 ? 18 ALA H CB 1 +ATOM 13460 N N . GLN H 1 19 ? 70.656 -41.913 15.932 1.00 84.97 ? 19 GLN H N 1 +ATOM 13461 C CA . GLN H 1 19 ? 71.006 -41.575 14.551 1.00 119.18 ? 19 GLN H CA 1 +ATOM 13462 C C . GLN H 1 19 ? 70.580 -40.144 14.216 1.00 118.00 ? 19 GLN H C 1 +ATOM 13463 O O . GLN H 1 19 ? 71.352 -39.352 13.634 1.00 128.72 ? 19 GLN H O 1 +ATOM 13464 C CB . GLN H 1 19 ? 70.352 -42.565 13.574 1.00 123.67 ? 19 GLN H CB 1 +ATOM 13465 C CG . GLN H 1 19 ? 70.744 -42.374 12.108 1.00 135.50 ? 19 GLN H CG 1 +ATOM 13466 C CD . GLN H 1 19 ? 72.245 -42.406 11.882 1.00 134.85 ? 19 GLN H CD 1 +ATOM 13467 O OE1 . GLN H 1 19 ? 72.893 -43.432 12.087 1.00 144.40 ? 19 GLN H OE1 1 +ATOM 13468 N NE2 . GLN H 1 19 ? 72.812 -41.266 11.496 1.00 141.15 ? 19 GLN H NE2 1 +ATOM 13469 N N . SER H 1 20 ? 69.327 -39.854 14.531 1.00 91.68 ? 20 SER H N 1 +ATOM 13470 C CA . SER H 1 20 ? 68.777 -38.541 14.367 1.00 91.33 ? 20 SER H CA 1 +ATOM 13471 C C . SER H 1 20 ? 69.783 -37.498 14.863 1.00 109.11 ? 20 SER H C 1 +ATOM 13472 O O . SER H 1 20 ? 70.039 -36.486 14.189 1.00 92.27 ? 20 SER H O 1 +ATOM 13473 C CB . SER H 1 20 ? 67.462 -38.468 15.150 1.00 100.46 ? 20 SER H CB 1 +ATOM 13474 O OG . SER H 1 20 ? 66.594 -39.536 14.792 1.00 85.88 ? 20 SER H OG 1 +ATOM 13475 N N . TYR H 1 21 ? 70.301 -37.714 16.076 1.00 133.94 ? 21 TYR H N 1 +ATOM 13476 C CA . TYR H 1 21 ? 71.271 -36.791 16.702 1.00 148.83 ? 21 TYR H CA 1 +ATOM 13477 C C . TYR H 1 21 ? 72.515 -36.599 15.836 1.00 126.23 ? 21 TYR H C 1 +ATOM 13478 O O . TYR H 1 21 ? 72.953 -35.467 15.596 1.00 66.76 ? 21 TYR H O 1 +ATOM 13479 C CB . TYR H 1 21 ? 71.683 -37.318 18.085 1.00 157.55 ? 21 TYR H CB 1 +ATOM 13480 C CG . TYR H 1 21 ? 72.664 -36.429 18.824 1.00 157.85 ? 21 TYR H CG 1 +ATOM 13481 C CD1 . TYR H 1 21 ? 72.246 -35.250 19.431 1.00 169.91 ? 21 TYR H CD1 1 +ATOM 13482 C CD2 . TYR H 1 21 ? 74.004 -36.760 18.897 1.00 176.54 ? 21 TYR H CD2 1 +ATOM 13483 C CE1 . TYR H 1 21 ? 73.131 -34.422 20.087 1.00 173.65 ? 21 TYR H CE1 1 +ATOM 13484 C CE2 . TYR H 1 21 ? 74.898 -35.934 19.561 1.00 183.72 ? 21 TYR H CE2 1 +ATOM 13485 C CZ . TYR H 1 21 ? 74.449 -34.767 20.158 1.00 168.53 ? 21 TYR H CZ 1 +ATOM 13486 O OH . TYR H 1 21 ? 75.320 -33.906 20.782 1.00 140.73 ? 21 TYR H OH 1 +ATOM 13487 N N . LYS H 1 22 ? 73.066 -37.718 15.369 1.00 137.09 ? 22 LYS H N 1 +ATOM 13488 C CA . LYS H 1 22 ? 74.288 -37.702 14.578 1.00 152.00 ? 22 LYS H CA 1 +ATOM 13489 C C . LYS H 1 22 ? 74.118 -36.914 13.283 1.00 168.44 ? 22 LYS H C 1 +ATOM 13490 O O . LYS H 1 22 ? 75.011 -36.162 12.879 1.00 193.55 ? 22 LYS H O 1 +ATOM 13491 C CB . LYS H 1 22 ? 74.730 -39.129 14.259 1.00 126.35 ? 22 LYS H CB 1 +ATOM 13492 C CG . LYS H 1 22 ? 75.631 -39.733 15.311 1.00 137.63 ? 22 LYS H CG 1 +ATOM 13493 C CD . LYS H 1 22 ? 77.082 -39.264 15.100 1.00 174.94 ? 22 LYS H CD 1 +ATOM 13494 C CE . LYS H 1 22 ? 77.908 -40.369 14.429 1.00 188.91 ? 22 LYS H CE 1 +ATOM 13495 N NZ . LYS H 1 22 ? 78.045 -41.560 15.311 1.00 201.00 ? 22 LYS H NZ 1 +ATOM 13496 N N . ASP H 1 23 ? 72.965 -37.087 12.644 1.00 156.94 ? 23 ASP H N 1 +ATOM 13497 C CA . ASP H 1 23 ? 72.609 -36.298 11.463 1.00 160.44 ? 23 ASP H CA 1 +ATOM 13498 C C . ASP H 1 23 ? 72.459 -34.817 11.810 1.00 166.05 ? 23 ASP H C 1 +ATOM 13499 O O . ASP H 1 23 ? 72.967 -33.946 11.103 1.00 144.36 ? 23 ASP H O 1 +ATOM 13500 C CB . ASP H 1 23 ? 71.297 -36.807 10.869 1.00 158.82 ? 23 ASP H CB 1 +ATOM 13501 C CG . ASP H 1 23 ? 71.424 -38.183 10.287 1.00 162.94 ? 23 ASP H CG 1 +ATOM 13502 O OD1 . ASP H 1 23 ? 72.451 -38.436 9.627 1.00 137.02 ? 23 ASP H OD1 1 +ATOM 13503 O OD2 . ASP H 1 23 ? 70.489 -38.997 10.470 1.00 199.45 ? 23 ASP H OD2 1 +ATOM 13504 N N . LEU H 1 24 ? 71.763 -34.554 12.915 1.00 165.48 ? 24 LEU H N 1 +ATOM 13505 C CA . LEU H 1 24 ? 71.425 -33.193 13.333 1.00 152.78 ? 24 LEU H CA 1 +ATOM 13506 C C . LEU H 1 24 ? 72.667 -32.368 13.667 1.00 150.09 ? 24 LEU H C 1 +ATOM 13507 O O . LEU H 1 24 ? 72.711 -31.149 13.412 1.00 130.55 ? 24 LEU H O 1 +ATOM 13508 C CB . LEU H 1 24 ? 70.491 -33.246 14.554 1.00 160.78 ? 24 LEU H CB 1 +ATOM 13509 C CG . LEU H 1 24 ? 69.995 -31.916 15.149 1.00 153.56 ? 24 LEU H CG 1 +ATOM 13510 C CD1 . LEU H 1 24 ? 68.755 -31.418 14.421 1.00 172.79 ? 24 LEU H CD1 1 +ATOM 13511 C CD2 . LEU H 1 24 ? 69.710 -32.082 16.630 1.00 142.15 ? 24 LEU H CD2 1 +ATOM 13512 N N . THR H 1 25 ? 73.659 -33.023 14.270 1.00 152.99 ? 25 THR H N 1 +ATOM 13513 C CA . THR H 1 25 ? 74.882 -32.340 14.688 1.00 154.78 ? 25 THR H CA 1 +ATOM 13514 C C . THR H 1 25 ? 75.783 -32.008 13.492 1.00 148.72 ? 25 THR H C 1 +ATOM 13515 O O . THR H 1 25 ? 76.297 -30.882 13.382 1.00 120.98 ? 25 THR H O 1 +ATOM 13516 C CB . THR H 1 25 ? 75.666 -33.179 15.719 1.00 148.88 ? 25 THR H CB 1 +ATOM 13517 O OG1 . THR H 1 25 ? 75.756 -34.540 15.271 1.00 165.03 ? 25 THR H OG1 1 +ATOM 13518 C CG2 . THR H 1 25 ? 74.977 -33.129 17.073 1.00 118.08 ? 25 THR H CG2 1 +ATOM 13519 N N . HIS H 1 26 ? 75.984 -32.995 12.617 1.00 151.52 ? 26 HIS H N 1 +ATOM 13520 C CA . HIS H 1 26 ? 76.901 -32.866 11.480 1.00 151.68 ? 26 HIS H CA 1 +ATOM 13521 C C . HIS H 1 26 ? 76.205 -32.192 10.288 1.00 124.46 ? 26 HIS H C 1 +ATOM 13522 O O . HIS H 1 26 ? 76.432 -32.549 9.133 1.00 159.99 ? 26 HIS H O 1 +ATOM 13523 C CB . HIS H 1 26 ? 77.475 -34.249 11.089 1.00 145.41 ? 26 HIS H CB 1 +ATOM 13524 C CG . HIS H 1 26 ? 78.341 -34.875 12.146 1.00 149.66 ? 26 HIS H CG 1 +ATOM 13525 N ND1 . HIS H 1 26 ? 77.838 -35.354 13.338 1.00 143.01 ? 26 HIS H ND1 1 +ATOM 13526 C CD2 . HIS H 1 26 ? 79.677 -35.100 12.187 1.00 165.49 ? 26 HIS H CD2 1 +ATOM 13527 C CE1 . HIS H 1 26 ? 78.826 -35.827 14.077 1.00 140.28 ? 26 HIS H CE1 1 +ATOM 13528 N NE2 . HIS H 1 26 ? 79.952 -35.689 13.400 1.00 172.79 ? 26 HIS H NE2 1 +ATOM 13529 N N . LEU H 1 27 ? 75.337 -31.232 10.568 1.00 93.91 ? 27 LEU H N 1 +ATOM 13530 C CA . LEU H 1 27 ? 74.684 -30.478 9.504 1.00 116.86 ? 27 LEU H CA 1 +ATOM 13531 C C . LEU H 1 27 ? 75.549 -29.282 9.141 1.00 101.07 ? 27 LEU H C 1 +ATOM 13532 O O . LEU H 1 27 ? 76.019 -28.573 10.027 1.00 101.66 ? 27 LEU H O 1 +ATOM 13533 C CB . LEU H 1 27 ? 73.275 -30.013 9.935 1.00 138.81 ? 27 LEU H CB 1 +ATOM 13534 C CG . LEU H 1 27 ? 72.135 -31.003 9.666 1.00 141.97 ? 27 LEU H CG 1 +ATOM 13535 C CD1 . LEU H 1 27 ? 70.875 -30.602 10.407 1.00 143.46 ? 27 LEU H CD1 1 +ATOM 13536 C CD2 . LEU H 1 27 ? 71.853 -31.120 8.174 1.00 146.20 ? 27 LEU H CD2 1 +ATOM 13537 N N . PRO H 1 28 ? 75.701 -29.009 7.836 1.00 98.60 ? 28 PRO H N 1 +ATOM 13538 C CA . PRO H 1 28 ? 76.486 -27.860 7.370 1.00 112.64 ? 28 PRO H CA 1 +ATOM 13539 C C . PRO H 1 28 ? 75.944 -26.540 7.879 1.00 101.94 ? 28 PRO H C 1 +ATOM 13540 O O . PRO H 1 28 ? 74.764 -26.290 7.747 1.00 103.64 ? 28 PRO H O 1 +ATOM 13541 C CB . PRO H 1 28 ? 76.342 -27.926 5.843 1.00 130.19 ? 28 PRO H CB 1 +ATOM 13542 C CG . PRO H 1 28 ? 75.085 -28.686 5.608 1.00 118.95 ? 28 PRO H CG 1 +ATOM 13543 C CD . PRO H 1 28 ? 75.012 -29.687 6.724 1.00 111.20 ? 28 PRO H CD 1 +ATOM 13544 N N . ALA H 1 29 ? 76.804 -25.709 8.469 1.00 127.07 ? 29 ALA H N 1 +ATOM 13545 C CA . ALA H 1 29 ? 76.354 -24.527 9.226 1.00 121.21 ? 29 ALA H CA 1 +ATOM 13546 C C . ALA H 1 29 ? 75.848 -23.385 8.307 1.00 102.27 ? 29 ALA H C 1 +ATOM 13547 O O . ALA H 1 29 ? 76.275 -23.261 7.162 1.00 96.37 ? 29 ALA H O 1 +ATOM 13548 C CB . ALA H 1 29 ? 77.464 -24.028 10.149 1.00 105.94 ? 29 ALA H CB 1 +ATOM 13549 N N . PRO H 1 30 ? 74.858 -22.618 8.783 1.00 92.81 ? 30 PRO H N 1 +ATOM 13550 C CA . PRO H 1 30 ? 74.292 -21.493 8.043 1.00 95.36 ? 30 PRO H CA 1 +ATOM 13551 C C . PRO H 1 30 ? 75.206 -20.288 8.124 1.00 87.29 ? 30 PRO H C 1 +ATOM 13552 O O . PRO H 1 30 ? 76.198 -20.322 8.869 1.00 64.96 ? 30 PRO H O 1 +ATOM 13553 C CB . PRO H 1 30 ? 72.994 -21.203 8.796 1.00 125.27 ? 30 PRO H CB 1 +ATOM 13554 C CG . PRO H 1 30 ? 73.261 -21.652 10.200 1.00 130.24 ? 30 PRO H CG 1 +ATOM 13555 C CD . PRO H 1 30 ? 74.212 -22.807 10.100 1.00 112.19 ? 30 PRO H CD 1 +ATOM 13556 N N . THR H 1 31 ? 74.829 -19.203 7.445 1.00 89.66 ? 31 THR H N 1 +ATOM 13557 C CA . THR H 1 31 ? 75.647 -17.975 7.443 1.00 128.91 ? 31 THR H CA 1 +ATOM 13558 C C . THR H 1 31 ? 75.683 -17.281 8.810 1.00 149.58 ? 31 THR H C 1 +ATOM 13559 O O . THR H 1 31 ? 76.641 -16.579 9.137 1.00 171.97 ? 31 THR H O 1 +ATOM 13560 C CB . THR H 1 31 ? 75.202 -16.949 6.361 1.00 114.63 ? 31 THR H CB 1 +ATOM 13561 O OG1 . THR H 1 31 ? 73.807 -16.669 6.483 1.00 115.55 ? 31 THR H OG1 1 +ATOM 13562 C CG2 . THR H 1 31 ? 75.491 -17.475 4.961 1.00 119.74 ? 31 THR H CG2 1 +ATOM 13563 N N . GLY H 1 32 ? 74.619 -17.454 9.586 1.00 155.94 ? 32 GLY H N 1 +ATOM 13564 C CA . GLY H 1 32 ? 74.607 -17.059 10.994 1.00 155.47 ? 32 GLY H CA 1 +ATOM 13565 C C . GLY H 1 32 ? 73.540 -17.853 11.713 1.00 135.23 ? 32 GLY H C 1 +ATOM 13566 O O . GLY H 1 32 ? 72.627 -18.375 11.065 1.00 185.89 ? 32 GLY H O 1 +ATOM 13567 N N . LYS H 1 33 ? 73.693 -18.049 13.020 1.00 110.93 ? 33 LYS H N 1 +ATOM 13568 C CA . LYS H 1 33 ? 72.680 -18.796 13.760 1.00 102.74 ? 33 LYS H CA 1 +ATOM 13569 C C . LYS H 1 33 ? 71.385 -17.978 13.837 1.00 125.04 ? 33 LYS H C 1 +ATOM 13570 O O . LYS H 1 33 ? 71.433 -16.747 13.770 1.00 111.83 ? 33 LYS H O 1 +ATOM 13571 C CB . LYS H 1 33 ? 73.158 -19.163 15.153 1.00 83.83 ? 33 LYS H CB 1 +ATOM 13572 C CG . LYS H 1 33 ? 73.842 -20.507 15.250 1.00 76.25 ? 33 LYS H CG 1 +ATOM 13573 C CD . LYS H 1 33 ? 74.423 -20.720 16.643 1.00 85.47 ? 33 LYS H CD 1 +ATOM 13574 C CE . LYS H 1 33 ? 75.593 -21.686 16.613 1.00 95.56 ? 33 LYS H CE 1 +ATOM 13575 N NZ . LYS H 1 33 ? 76.278 -21.784 17.929 1.00 78.63 ? 33 LYS H NZ 1 +ATOM 13576 N N . ILE H 1 34 ? 70.240 -18.664 13.916 1.00 132.39 ? 34 ILE H N 1 +ATOM 13577 C CA . ILE H 1 34 ? 68.945 -17.994 13.889 1.00 130.94 ? 34 ILE H CA 1 +ATOM 13578 C C . ILE H 1 34 ? 68.367 -18.043 15.305 1.00 125.77 ? 34 ILE H C 1 +ATOM 13579 O O . ILE H 1 34 ? 68.621 -18.989 16.055 1.00 81.42 ? 34 ILE H O 1 +ATOM 13580 C CB . ILE H 1 34 ? 68.008 -18.606 12.810 1.00 151.30 ? 34 ILE H CB 1 +ATOM 13581 C CG1 . ILE H 1 34 ? 68.560 -18.328 11.406 1.00 147.22 ? 34 ILE H CG1 1 +ATOM 13582 C CG2 . ILE H 1 34 ? 66.602 -18.020 12.867 1.00 166.13 ? 34 ILE H CG2 1 +ATOM 13583 C CD1 . ILE H 1 34 ? 68.908 -19.586 10.639 1.00 155.28 ? 34 ILE H CD1 1 +ATOM 13584 N N . PHE H 1 35 ? 67.735 -16.932 15.703 1.00 127.29 ? 35 PHE H N 1 +ATOM 13585 C CA . PHE H 1 35 ? 67.134 -16.760 17.039 1.00 85.35 ? 35 PHE H CA 1 +ATOM 13586 C C . PHE H 1 35 ? 65.747 -17.374 17.095 1.00 80.10 ? 35 PHE H C 1 +ATOM 13587 O O . PHE H 1 35 ? 64.894 -17.044 16.243 1.00 90.05 ? 35 PHE H O 1 +ATOM 13588 C CB . PHE H 1 35 ? 66.974 -15.287 17.317 1.00 67.95 ? 35 PHE H CB 1 +ATOM 13589 C CG . PHE H 1 35 ? 68.171 -14.644 17.890 1.00 64.39 ? 35 PHE H CG 1 +ATOM 13590 C CD1 . PHE H 1 35 ? 68.880 -15.252 18.921 1.00 70.85 ? 35 PHE H CD1 1 +ATOM 13591 C CD2 . PHE H 1 35 ? 68.528 -13.372 17.483 1.00 63.89 ? 35 PHE H CD2 1 +ATOM 13592 C CE1 . PHE H 1 35 ? 69.981 -14.630 19.482 1.00 78.24 ? 35 PHE H CE1 1 +ATOM 13593 C CE2 . PHE H 1 35 ? 69.606 -12.730 18.059 1.00 75.29 ? 35 PHE H CE2 1 +ATOM 13594 C CZ . PHE H 1 35 ? 70.342 -13.361 19.052 1.00 83.73 ? 35 PHE H CZ 1 +ATOM 13595 N N . VAL H 1 36 ? 65.519 -18.273 18.045 1.00 54.26 ? 36 VAL H N 1 +ATOM 13596 C CA . VAL H 1 36 ? 64.284 -19.020 18.021 1.00 62.27 ? 36 VAL H CA 1 +ATOM 13597 C C . VAL H 1 36 ? 63.649 -19.092 19.380 1.00 73.81 ? 36 VAL H C 1 +ATOM 13598 O O . VAL H 1 36 ? 64.316 -19.031 20.397 1.00 82.81 ? 36 VAL H O 1 +ATOM 13599 C CB . VAL H 1 36 ? 64.482 -20.451 17.526 1.00 82.88 ? 36 VAL H CB 1 +ATOM 13600 C CG1 . VAL H 1 36 ? 65.156 -21.321 18.587 1.00 73.19 ? 36 VAL H CG1 1 +ATOM 13601 C CG2 . VAL H 1 36 ? 63.139 -21.060 17.117 1.00 111.22 ? 36 VAL H CG2 1 +ATOM 13602 N N . SER H 1 37 ? 62.322 -19.180 19.398 1.00 88.56 ? 37 SER H N 1 +ATOM 13603 C CA . SER H 1 37 ? 61.580 -19.216 20.650 1.00 76.19 ? 37 SER H CA 1 +ATOM 13604 C C . SER H 1 37 ? 60.774 -20.484 20.671 1.00 58.13 ? 37 SER H C 1 +ATOM 13605 O O . SER H 1 37 ? 60.020 -20.739 19.730 1.00 43.92 ? 37 SER H O 1 +ATOM 13606 C CB . SER H 1 37 ? 60.637 -17.997 20.746 1.00 79.96 ? 37 SER H CB 1 +ATOM 13607 O OG . SER H 1 37 ? 61.330 -16.787 21.036 1.00 49.46 ? 37 SER H OG 1 +ATOM 13608 N N . VAL H 1 38 ? 60.846 -21.223 21.762 1.00 49.80 ? 38 VAL H N 1 +ATOM 13609 C CA . VAL H 1 38 ? 59.835 -22.241 21.974 1.00 78.58 ? 38 VAL H CA 1 +ATOM 13610 C C . VAL H 1 38 ? 59.068 -21.958 23.271 1.00 96.54 ? 38 VAL H C 1 +ATOM 13611 O O . VAL H 1 38 ? 59.657 -21.986 24.347 1.00 99.95 ? 38 VAL H O 1 +ATOM 13612 C CB . VAL H 1 38 ? 60.450 -23.644 22.066 1.00 87.19 ? 38 VAL H CB 1 +ATOM 13613 C CG1 . VAL H 1 38 ? 59.380 -24.695 22.338 1.00 84.71 ? 38 VAL H CG1 1 +ATOM 13614 C CG2 . VAL H 1 38 ? 61.209 -23.989 20.793 1.00 89.76 ? 38 VAL H CG2 1 +ATOM 13615 N N . TYR H 1 39 ? 57.738 -21.791 23.162 1.00 94.63 ? 39 TYR H N 1 +ATOM 13616 C CA . TYR H 1 39 ? 56.873 -21.540 24.315 1.00 73.30 ? 39 TYR H CA 1 +ATOM 13617 C C . TYR H 1 39 ? 56.340 -22.860 24.924 1.00 75.05 ? 39 TYR H C 1 +ATOM 13618 O O . TYR H 1 39 ? 56.530 -23.128 26.111 1.00 65.26 ? 39 TYR H O 1 +ATOM 13619 C CB . TYR H 1 39 ? 55.738 -20.596 23.912 1.00 72.65 ? 39 TYR H CB 1 +ATOM 13620 C CG . TYR H 1 39 ? 56.138 -19.100 23.958 1.00 66.83 ? 39 TYR H CG 1 +ATOM 13621 C CD1 . TYR H 1 39 ? 56.856 -18.502 22.922 1.00 40.27 ? 39 TYR H CD1 1 +ATOM 13622 C CD2 . TYR H 1 39 ? 55.742 -18.291 25.043 1.00 74.03 ? 39 TYR H CD2 1 +ATOM 13623 C CE1 . TYR H 1 39 ? 57.141 -17.157 22.941 1.00 30.50 ? 39 TYR H CE1 1 +ATOM 13624 C CE2 . TYR H 1 39 ? 56.077 -16.947 25.101 1.00 53.09 ? 39 TYR H CE2 1 +ATOM 13625 C CZ . TYR H 1 39 ? 56.781 -16.397 24.035 1.00 38.61 ? 39 TYR H CZ 1 +ATOM 13626 O OH . TYR H 1 39 ? 57.150 -15.084 24.172 1.00 40.18 ? 39 TYR H OH 1 +ATOM 13627 N N . ASN H 1 40 ? 55.756 -23.722 24.099 1.00 73.29 ? 40 ASN H N 1 +ATOM 13628 C CA . ASN H 1 40 ? 55.239 -24.997 24.596 1.00 74.00 ? 40 ASN H CA 1 +ATOM 13629 C C . ASN H 1 40 ? 54.840 -25.990 23.510 1.00 76.26 ? 40 ASN H C 1 +ATOM 13630 O O . ASN H 1 40 ? 54.176 -25.634 22.517 1.00 92.92 ? 40 ASN H O 1 +ATOM 13631 C CB . ASN H 1 40 ? 54.016 -24.740 25.449 1.00 103.84 ? 40 ASN H CB 1 +ATOM 13632 C CG . ASN H 1 40 ? 53.677 -25.915 26.332 1.00 127.31 ? 40 ASN H CG 1 +ATOM 13633 O OD1 . ASN H 1 40 ? 52.609 -26.520 26.197 1.00 150.31 ? 40 ASN H OD1 1 +ATOM 13634 N ND2 . ASN H 1 40 ? 54.578 -26.238 27.251 1.00 136.02 ? 40 ASN H ND2 1 +ATOM 13635 N N . ILE H 1 41 ? 55.248 -27.239 23.692 1.00 62.69 ? 41 ILE H N 1 +ATOM 13636 C CA . ILE H 1 41 ? 54.784 -28.326 22.843 1.00 71.12 ? 41 ILE H CA 1 +ATOM 13637 C C . ILE H 1 41 ? 54.009 -29.304 23.719 1.00 71.93 ? 41 ILE H C 1 +ATOM 13638 O O . ILE H 1 41 ? 54.600 -29.948 24.590 1.00 68.29 ? 41 ILE H O 1 +ATOM 13639 C CB . ILE H 1 41 ? 55.953 -29.053 22.109 1.00 68.15 ? 41 ILE H CB 1 +ATOM 13640 C CG1 . ILE H 1 41 ? 56.389 -28.281 20.855 1.00 75.00 ? 41 ILE H CG1 1 +ATOM 13641 C CG2 . ILE H 1 41 ? 55.498 -30.417 21.615 1.00 80.81 ? 41 ILE H CG2 1 +ATOM 13642 C CD1 . ILE H 1 41 ? 57.116 -26.987 21.111 1.00 78.30 ? 41 ILE H CD1 1 +ATOM 13643 N N . GLN H 1 42 ? 52.705 -29.461 23.452 1.00 84.61 ? 42 GLN H N 1 +ATOM 13644 C CA . GLN H 1 42 ? 51.805 -30.220 24.350 1.00 80.10 ? 42 GLN H CA 1 +ATOM 13645 C C . GLN H 1 42 ? 51.676 -31.694 24.025 1.00 68.55 ? 42 GLN H C 1 +ATOM 13646 O O . GLN H 1 42 ? 52.012 -32.133 22.909 1.00 72.27 ? 42 GLN H O 1 +ATOM 13647 C CB . GLN H 1 42 ? 50.401 -29.666 24.314 1.00 83.36 ? 42 GLN H CB 1 +ATOM 13648 C CG . GLN H 1 42 ? 50.284 -28.250 24.829 1.00 99.11 ? 42 GLN H CG 1 +ATOM 13649 C CD . GLN H 1 42 ? 49.770 -27.299 23.769 1.00 130.40 ? 42 GLN H CD 1 +ATOM 13650 O OE1 . GLN H 1 42 ? 48.553 -27.156 23.585 1.00 176.91 ? 42 GLN H OE1 1 +ATOM 13651 N NE2 . GLN H 1 42 ? 50.687 -26.691 23.013 1.00 120.13 ? 42 GLN H NE2 1 +ATOM 13652 N N . ASP H 1 43 ? 51.316 -32.465 25.050 1.00 52.24 ? 43 ASP H N 1 +ATOM 13653 C CA . ASP H 1 43 ? 51.059 -33.893 24.883 1.00 63.93 ? 43 ASP H CA 1 +ATOM 13654 C C . ASP H 1 43 ? 49.663 -34.094 24.352 1.00 58.76 ? 43 ASP H C 1 +ATOM 13655 O O . ASP H 1 43 ? 48.792 -34.559 25.091 1.00 49.92 ? 43 ASP H O 1 +ATOM 13656 C CB . ASP H 1 43 ? 51.230 -34.633 26.232 1.00 78.31 ? 43 ASP H CB 1 +ATOM 13657 C CG . ASP H 1 43 ? 51.135 -36.171 26.094 1.00 94.90 ? 43 ASP H CG 1 +ATOM 13658 O OD1 . ASP H 1 43 ? 51.800 -36.737 25.199 1.00 113.74 ? 43 ASP H OD1 1 +ATOM 13659 O OD2 . ASP H 1 43 ? 50.371 -36.819 26.845 1.00 92.90 ? 43 ASP H OD2 1 +ATOM 13660 N N . GLU H 1 44 ? 49.427 -33.649 23.119 1.00 61.27 ? 44 GLU H N 1 +ATOM 13661 C CA . GLU H 1 44 ? 48.063 -33.596 22.571 1.00 73.39 ? 44 GLU H CA 1 +ATOM 13662 C C . GLU H 1 44 ? 47.551 -35.014 22.282 1.00 80.69 ? 44 GLU H C 1 +ATOM 13663 O O . GLU H 1 44 ? 46.576 -35.199 21.533 1.00 91.79 ? 44 GLU H O 1 +ATOM 13664 C CB . GLU H 1 44 ? 48.014 -32.689 21.306 1.00 87.20 ? 44 GLU H CB 1 +ATOM 13665 C CG . GLU H 1 44 ? 47.708 -31.199 21.550 1.00 103.38 ? 44 GLU H CG 1 +ATOM 13666 C CD . GLU H 1 44 ? 47.704 -30.320 20.271 1.00 126.50 ? 44 GLU H CD 1 +ATOM 13667 O OE1 . GLU H 1 44 ? 47.126 -30.707 19.213 1.00 99.62 ? 44 GLU H OE1 1 +ATOM 13668 O OE2 . GLU H 1 44 ? 48.250 -29.189 20.327 1.00 133.80 ? 44 GLU H OE2 1 +ATOM 13669 N N . THR H 1 45 ? 48.242 -36.012 22.841 1.00 90.84 ? 45 THR H N 1 +ATOM 13670 C CA . THR H 1 45 ? 48.050 -37.422 22.449 1.00 106.94 ? 45 THR H CA 1 +ATOM 13671 C C . THR H 1 45 ? 46.794 -38.032 23.034 1.00 94.32 ? 45 THR H C 1 +ATOM 13672 O O . THR H 1 45 ? 46.079 -38.755 22.360 1.00 126.42 ? 45 THR H O 1 +ATOM 13673 C CB . THR H 1 45 ? 49.270 -38.307 22.786 1.00 91.63 ? 45 THR H CB 1 +ATOM 13674 O OG1 . THR H 1 45 ? 49.147 -39.563 22.135 1.00 114.49 ? 45 THR H OG1 1 +ATOM 13675 C CG2 . THR H 1 45 ? 49.407 -38.556 24.273 1.00 78.08 ? 45 THR H CG2 1 +ATOM 13676 N N . GLY H 1 46 ? 46.516 -37.737 24.291 1.00 93.12 ? 46 GLY H N 1 +ATOM 13677 C CA . GLY H 1 46 ? 45.237 -38.122 24.918 1.00 100.55 ? 46 GLY H CA 1 +ATOM 13678 C C . GLY H 1 46 ? 45.302 -39.493 25.571 1.00 90.13 ? 46 GLY H C 1 +ATOM 13679 O O . GLY H 1 46 ? 44.272 -40.134 25.874 1.00 91.10 ? 46 GLY H O 1 +ATOM 13680 N N . GLN H 1 47 ? 46.503 -39.924 25.886 1.00 76.10 ? 47 GLN H N 1 +ATOM 13681 C CA . GLN H 1 47 ? 46.663 -41.304 26.131 1.00 67.24 ? 47 GLN H CA 1 +ATOM 13682 C C . GLN H 1 47 ? 47.432 -41.585 27.412 1.00 55.24 ? 47 GLN H C 1 +ATOM 13683 O O . GLN H 1 47 ? 48.379 -40.879 27.744 1.00 63.29 ? 47 GLN H O 1 +ATOM 13684 C CB . GLN H 1 47 ? 47.307 -41.888 24.938 1.00 52.60 ? 47 GLN H CB 1 +ATOM 13685 C CG . GLN H 1 47 ? 46.413 -41.899 23.723 1.00 60.70 ? 47 GLN H CG 1 +ATOM 13686 C CD . GLN H 1 47 ? 45.035 -42.484 24.014 1.00 81.45 ? 47 GLN H CD 1 +ATOM 13687 O OE1 . GLN H 1 47 ? 44.873 -43.686 24.205 1.00 72.06 ? 47 GLN H OE1 1 +ATOM 13688 N NE2 . GLN H 1 47 ? 44.029 -41.640 24.012 1.00 137.90 ? 47 GLN H NE2 1 +ATOM 13689 N N . PHE H 1 48 ? 46.917 -42.547 28.164 1.00 45.38 ? 48 PHE H N 1 +ATOM 13690 C CA . PHE H 1 48 ? 47.511 -42.992 29.390 1.00 57.85 ? 48 PHE H CA 1 +ATOM 13691 C C . PHE H 1 48 ? 47.820 -44.478 29.355 1.00 79.01 ? 48 PHE H C 1 +ATOM 13692 O O . PHE H 1 48 ? 47.348 -45.208 28.481 1.00 128.12 ? 48 PHE H O 1 +ATOM 13693 C CB . PHE H 1 48 ? 46.577 -42.726 30.562 1.00 55.10 ? 48 PHE H CB 1 +ATOM 13694 C CG . PHE H 1 48 ? 46.376 -41.287 30.820 1.00 41.97 ? 48 PHE H CG 1 +ATOM 13695 C CD1 . PHE H 1 48 ? 45.675 -40.562 29.970 1.00 37.05 ? 48 PHE H CD1 1 +ATOM 13696 C CD2 . PHE H 1 48 ? 47.000 -40.682 31.888 1.00 53.71 ? 48 PHE H CD2 1 +ATOM 13697 C CE1 . PHE H 1 48 ? 45.541 -39.230 30.144 1.00 52.12 ? 48 PHE H CE1 1 +ATOM 13698 C CE2 . PHE H 1 48 ? 46.860 -39.361 32.086 1.00 55.77 ? 48 PHE H CE2 1 +ATOM 13699 C CZ . PHE H 1 48 ? 46.134 -38.626 31.203 1.00 62.08 ? 48 PHE H CZ 1 +ATOM 13700 N N . LYS H 1 49 ? 48.612 -44.918 30.326 1.00 77.96 ? 49 LYS H N 1 +ATOM 13701 C CA . LYS H 1 49 ? 49.069 -46.284 30.353 1.00 90.80 ? 49 LYS H CA 1 +ATOM 13702 C C . LYS H 1 49 ? 47.942 -47.148 30.886 1.00 72.94 ? 49 LYS H C 1 +ATOM 13703 O O . LYS H 1 49 ? 47.202 -46.722 31.773 1.00 51.53 ? 49 LYS H O 1 +ATOM 13704 C CB . LYS H 1 49 ? 50.375 -46.422 31.194 1.00 115.25 ? 49 LYS H CB 1 +ATOM 13705 C CG . LYS H 1 49 ? 51.565 -45.705 30.550 1.00 112.49 ? 49 LYS H CG 1 +ATOM 13706 C CD . LYS H 1 49 ? 52.928 -45.946 31.167 1.00 99.41 ? 49 LYS H CD 1 +ATOM 13707 C CE . LYS H 1 49 ? 53.952 -45.284 30.240 1.00 115.70 ? 49 LYS H CE 1 +ATOM 13708 N NZ . LYS H 1 49 ? 55.382 -45.444 30.630 1.00 153.74 ? 49 LYS H NZ 1 +ATOM 13709 N N . PRO H 1 50 ? 47.840 -48.384 30.365 1.00 67.76 ? 50 PRO H N 1 +ATOM 13710 C CA . PRO H 1 50 ? 46.916 -49.392 30.882 1.00 67.21 ? 50 PRO H CA 1 +ATOM 13711 C C . PRO H 1 50 ? 47.327 -50.030 32.200 1.00 84.18 ? 50 PRO H C 1 +ATOM 13712 O O . PRO H 1 50 ? 48.487 -49.898 32.640 1.00 128.90 ? 50 PRO H O 1 +ATOM 13713 C CB . PRO H 1 50 ? 46.896 -50.434 29.760 1.00 63.86 ? 50 PRO H CB 1 +ATOM 13714 C CG . PRO H 1 50 ? 48.233 -50.338 29.129 1.00 59.61 ? 50 PRO H CG 1 +ATOM 13715 C CD . PRO H 1 50 ? 48.672 -48.908 29.262 1.00 57.81 ? 50 PRO H CD 1 +ATOM 13716 N N . TYR H 1 51 ? 46.416 -50.782 32.808 1.00 92.99 ? 51 TYR H N 1 +ATOM 13717 C CA . TYR H 1 51 ? 46.801 -51.627 33.948 1.00 117.31 ? 51 TYR H CA 1 +ATOM 13718 C C . TYR H 1 51 ? 48.059 -52.442 33.605 1.00 122.15 ? 51 TYR H C 1 +ATOM 13719 O O . TYR H 1 51 ? 48.120 -53.021 32.513 1.00 166.83 ? 51 TYR H O 1 +ATOM 13720 C CB . TYR H 1 51 ? 45.666 -52.582 34.341 1.00 98.21 ? 51 TYR H CB 1 +ATOM 13721 C CG . TYR H 1 51 ? 45.908 -53.188 35.702 1.00 92.10 ? 51 TYR H CG 1 +ATOM 13722 C CD1 . TYR H 1 51 ? 45.515 -52.514 36.844 1.00 99.62 ? 51 TYR H CD1 1 +ATOM 13723 C CD2 . TYR H 1 51 ? 46.549 -54.414 35.857 1.00 104.33 ? 51 TYR H CD2 1 +ATOM 13724 C CE1 . TYR H 1 51 ? 45.747 -53.031 38.107 1.00 106.37 ? 51 TYR H CE1 1 +ATOM 13725 C CE2 . TYR H 1 51 ? 46.763 -54.960 37.129 1.00 105.88 ? 51 TYR H CE2 1 +ATOM 13726 C CZ . TYR H 1 51 ? 46.386 -54.233 38.248 1.00 107.81 ? 51 TYR H CZ 1 +ATOM 13727 O OH . TYR H 1 51 ? 46.551 -54.709 39.529 1.00 140.68 ? 51 TYR H OH 1 +ATOM 13728 N N . PRO H 1 52 ? 49.062 -52.495 34.517 1.00 89.33 ? 52 PRO H N 1 +ATOM 13729 C CA . PRO H 1 52 ? 49.043 -52.086 35.919 1.00 103.07 ? 52 PRO H CA 1 +ATOM 13730 C C . PRO H 1 52 ? 49.606 -50.729 36.211 1.00 127.72 ? 52 PRO H C 1 +ATOM 13731 O O . PRO H 1 52 ? 49.883 -50.438 37.391 1.00 170.65 ? 52 PRO H O 1 +ATOM 13732 C CB . PRO H 1 52 ? 49.948 -53.115 36.589 1.00 111.69 ? 52 PRO H CB 1 +ATOM 13733 C CG . PRO H 1 52 ? 50.968 -53.412 35.540 1.00 110.45 ? 52 PRO H CG 1 +ATOM 13734 C CD . PRO H 1 52 ? 50.237 -53.330 34.220 1.00 95.68 ? 52 PRO H CD 1 +ATOM 13735 N N . ALA H 1 53 ? 49.710 -49.876 35.195 1.00 115.36 ? 53 ALA H N 1 +ATOM 13736 C CA . ALA H 1 53 ? 50.176 -48.524 35.451 1.00 129.84 ? 53 ALA H CA 1 +ATOM 13737 C C . ALA H 1 53 ? 49.212 -47.735 36.356 1.00 103.48 ? 53 ALA H C 1 +ATOM 13738 O O . ALA H 1 53 ? 48.014 -48.082 36.478 1.00 82.75 ? 53 ALA H O 1 +ATOM 13739 C CB . ALA H 1 53 ? 50.394 -47.791 34.145 1.00 122.51 ? 53 ALA H CB 1 +ATOM 13740 N N . SER H 1 54 ? 49.737 -46.688 36.993 1.00 80.49 ? 54 SER H N 1 +ATOM 13741 C CA . SER H 1 54 ? 48.861 -45.730 37.631 1.00 82.71 ? 54 SER H CA 1 +ATOM 13742 C C . SER H 1 54 ? 47.927 -45.126 36.587 1.00 84.73 ? 54 SER H C 1 +ATOM 13743 O O . SER H 1 54 ? 48.271 -44.912 35.415 1.00 60.18 ? 54 SER H O 1 +ATOM 13744 C CB . SER H 1 54 ? 49.617 -44.611 38.318 1.00 86.48 ? 54 SER H CB 1 +ATOM 13745 O OG . SER H 1 54 ? 48.800 -43.450 38.500 1.00 74.95 ? 54 SER H OG 1 +ATOM 13746 N N . ASN H 1 55 ? 46.688 -44.924 37.015 1.00 79.99 ? 55 ASN H N 1 +ATOM 13747 C CA . ASN H 1 55 ? 45.670 -44.335 36.168 1.00 71.32 ? 55 ASN H CA 1 +ATOM 13748 C C . ASN H 1 55 ? 46.179 -43.073 35.497 1.00 69.99 ? 55 ASN H C 1 +ATOM 13749 O O . ASN H 1 55 ? 45.750 -42.696 34.376 1.00 59.12 ? 55 ASN H O 1 +ATOM 13750 C CB . ASN H 1 55 ? 44.459 -44.019 37.021 1.00 71.95 ? 55 ASN H CB 1 +ATOM 13751 C CG . ASN H 1 55 ? 43.242 -43.732 36.204 1.00 111.40 ? 55 ASN H CG 1 +ATOM 13752 O OD1 . ASN H 1 55 ? 43.123 -44.120 35.038 1.00 171.62 ? 55 ASN H OD1 1 +ATOM 13753 N ND2 . ASN H 1 55 ? 42.286 -43.116 36.839 1.00 133.35 ? 55 ASN H ND2 1 +ATOM 13754 N N . PHE H 1 56 ? 47.109 -42.423 36.197 1.00 91.80 ? 56 PHE H N 1 +ATOM 13755 C CA . PHE H 1 56 ? 47.545 -41.073 35.849 1.00 103.29 ? 56 PHE H CA 1 +ATOM 13756 C C . PHE H 1 56 ? 48.809 -41.097 35.045 1.00 96.24 ? 56 PHE H C 1 +ATOM 13757 O O . PHE H 1 56 ? 49.345 -40.025 34.717 1.00 121.08 ? 56 PHE H O 1 +ATOM 13758 C CB . PHE H 1 56 ? 47.846 -40.211 37.093 1.00 80.51 ? 56 PHE H CB 1 +ATOM 13759 C CG . PHE H 1 56 ? 46.686 -40.009 37.991 1.00 59.59 ? 56 PHE H CG 1 +ATOM 13760 C CD1 . PHE H 1 56 ? 45.533 -39.413 37.554 1.00 48.99 ? 56 PHE H CD1 1 +ATOM 13761 C CD2 . PHE H 1 56 ? 46.739 -40.492 39.263 1.00 70.36 ? 56 PHE H CD2 1 +ATOM 13762 C CE1 . PHE H 1 56 ? 44.433 -39.356 38.370 1.00 59.58 ? 56 PHE H CE1 1 +ATOM 13763 C CE2 . PHE H 1 56 ? 45.665 -40.355 40.121 1.00 76.56 ? 56 PHE H CE2 1 +ATOM 13764 C CZ . PHE H 1 56 ? 44.500 -39.800 39.664 1.00 69.46 ? 56 PHE H CZ 1 +ATOM 13765 N N . SER H 1 57 ? 49.355 -42.273 34.800 1.00 71.27 ? 57 SER H N 1 +ATOM 13766 C CA . SER H 1 57 ? 50.596 -42.305 34.056 1.00 97.29 ? 57 SER H CA 1 +ATOM 13767 C C . SER H 1 57 ? 50.298 -42.042 32.571 1.00 61.97 ? 57 SER H C 1 +ATOM 13768 O O . SER H 1 57 ? 49.631 -42.838 31.905 1.00 66.08 ? 57 SER H O 1 +ATOM 13769 C CB . SER H 1 57 ? 51.333 -43.634 34.287 1.00 137.35 ? 57 SER H CB 1 +ATOM 13770 O OG . SER H 1 57 ? 51.936 -43.657 35.587 1.00 103.12 ? 57 SER H OG 1 +ATOM 13771 N N . THR H 1 58 ? 50.796 -40.925 32.070 1.00 45.00 ? 58 THR H N 1 +ATOM 13772 C CA . THR H 1 58 ? 50.653 -40.632 30.677 1.00 66.46 ? 58 THR H CA 1 +ATOM 13773 C C . THR H 1 58 ? 51.441 -41.585 29.797 1.00 70.58 ? 58 THR H C 1 +ATOM 13774 O O . THR H 1 58 ? 52.484 -42.079 30.142 1.00 61.60 ? 58 THR H O 1 +ATOM 13775 C CB . THR H 1 58 ? 51.141 -39.232 30.382 1.00 78.77 ? 58 THR H CB 1 +ATOM 13776 O OG1 . THR H 1 58 ? 52.530 -39.141 30.693 1.00 111.16 ? 58 THR H OG1 1 +ATOM 13777 C CG2 . THR H 1 58 ? 50.408 -38.265 31.249 1.00 90.95 ? 58 THR H CG2 1 +ATOM 13778 N N . ALA H 1 59 ? 50.983 -41.757 28.588 1.00 99.75 ? 59 ALA H N 1 +ATOM 13779 C CA . ALA H 1 59 ? 51.678 -42.683 27.740 1.00 99.22 ? 59 ALA H CA 1 +ATOM 13780 C C . ALA H 1 59 ? 52.946 -42.060 27.208 1.00 65.78 ? 59 ALA H C 1 +ATOM 13781 O O . ALA H 1 59 ? 53.833 -42.772 26.743 1.00 87.63 ? 59 ALA H O 1 +ATOM 13782 C CB . ALA H 1 59 ? 50.787 -43.144 26.609 1.00 113.23 ? 59 ALA H CB 1 +ATOM 13783 N N . VAL H 1 60 ? 53.031 -40.749 27.273 1.00 46.02 ? 60 VAL H N 1 +ATOM 13784 C CA . VAL H 1 60 ? 54.107 -40.049 26.644 1.00 65.19 ? 60 VAL H CA 1 +ATOM 13785 C C . VAL H 1 60 ? 54.620 -39.036 27.654 1.00 79.32 ? 60 VAL H C 1 +ATOM 13786 O O . VAL H 1 60 ? 53.835 -38.348 28.291 1.00 99.57 ? 60 VAL H O 1 +ATOM 13787 C CB . VAL H 1 60 ? 53.612 -39.327 25.352 1.00 70.37 ? 60 VAL H CB 1 +ATOM 13788 C CG1 . VAL H 1 60 ? 54.726 -38.504 24.670 1.00 57.69 ? 60 VAL H CG1 1 +ATOM 13789 C CG2 . VAL H 1 60 ? 53.025 -40.345 24.372 1.00 62.85 ? 60 VAL H CG2 1 +ATOM 13790 N N . PRO H 1 61 ? 55.938 -38.824 27.691 1.00 87.54 ? 61 PRO H N 1 +ATOM 13791 C CA . PRO H 1 61 ? 56.458 -37.817 28.607 1.00 109.31 ? 61 PRO H CA 1 +ATOM 13792 C C . PRO H 1 61 ? 56.057 -36.392 28.232 1.00 106.79 ? 61 PRO H C 1 +ATOM 13793 O O . PRO H 1 61 ? 55.950 -36.063 27.038 1.00 98.78 ? 61 PRO H O 1 +ATOM 13794 C CB . PRO H 1 61 ? 57.979 -37.987 28.498 1.00 119.11 ? 61 PRO H CB 1 +ATOM 13795 C CG . PRO H 1 61 ? 58.197 -38.642 27.181 1.00 107.54 ? 61 PRO H CG 1 +ATOM 13796 C CD . PRO H 1 61 ? 57.014 -39.538 26.992 1.00 99.45 ? 61 PRO H CD 1 +ATOM 13797 N N . GLN H 1 62 ? 55.858 -35.559 29.253 1.00 81.60 ? 62 GLN H N 1 +ATOM 13798 C CA . GLN H 1 62 ? 55.327 -34.216 29.051 1.00 94.41 ? 62 GLN H CA 1 +ATOM 13799 C C . GLN H 1 62 ? 56.426 -33.230 28.796 1.00 71.83 ? 62 GLN H C 1 +ATOM 13800 O O . GLN H 1 62 ? 56.368 -32.106 29.272 1.00 109.98 ? 62 GLN H O 1 +ATOM 13801 C CB . GLN H 1 62 ? 54.512 -33.769 30.289 1.00 126.08 ? 62 GLN H CB 1 +ATOM 13802 C CG . GLN H 1 62 ? 53.440 -34.752 30.743 1.00 123.59 ? 62 GLN H CG 1 +ATOM 13803 C CD . GLN H 1 62 ? 52.429 -35.042 29.653 1.00 108.05 ? 62 GLN H CD 1 +ATOM 13804 O OE1 . GLN H 1 62 ? 51.544 -34.247 29.388 1.00 103.80 ? 62 GLN H OE1 1 +ATOM 13805 N NE2 . GLN H 1 62 ? 52.603 -36.164 28.974 1.00 116.94 ? 62 GLN H NE2 1 +ATOM 13806 N N . SER H 1 63 ? 57.451 -33.662 28.102 1.00 59.32 ? 63 SER H N 1 +ATOM 13807 C CA . SER H 1 63 ? 58.736 -32.995 28.184 1.00 83.26 ? 63 SER H CA 1 +ATOM 13808 C C . SER H 1 63 ? 59.209 -32.546 26.818 1.00 78.54 ? 63 SER H C 1 +ATOM 13809 O O . SER H 1 63 ? 60.356 -32.132 26.639 1.00 84.63 ? 63 SER H O 1 +ATOM 13810 C CB . SER H 1 63 ? 59.785 -33.926 28.859 1.00 125.68 ? 63 SER H CB 1 +ATOM 13811 O OG . SER H 1 63 ? 60.026 -35.142 28.161 1.00 92.58 ? 63 SER H OG 1 +ATOM 13812 N N . ALA H 1 64 ? 58.324 -32.683 25.852 1.00 83.89 ? 64 ALA H N 1 +ATOM 13813 C CA . ALA H 1 64 ? 58.664 -32.464 24.459 1.00 109.81 ? 64 ALA H CA 1 +ATOM 13814 C C . ALA H 1 64 ? 59.292 -31.084 24.208 1.00 108.46 ? 64 ALA H C 1 +ATOM 13815 O O . ALA H 1 64 ? 60.215 -30.931 23.394 1.00 83.21 ? 64 ALA H O 1 +ATOM 13816 C CB . ALA H 1 64 ? 57.411 -32.647 23.618 1.00 117.91 ? 64 ALA H CB 1 +ATOM 13817 N N . THR H 1 65 ? 58.782 -30.087 24.921 1.00 114.04 ? 65 THR H N 1 +ATOM 13818 C CA . THR H 1 65 ? 59.220 -28.711 24.772 1.00 116.24 ? 65 THR H CA 1 +ATOM 13819 C C . THR H 1 65 ? 60.724 -28.601 24.944 1.00 127.77 ? 65 THR H C 1 +ATOM 13820 O O . THR H 1 65 ? 61.409 -27.978 24.130 1.00 115.76 ? 65 THR H O 1 +ATOM 13821 C CB . THR H 1 65 ? 58.562 -27.844 25.848 1.00 118.12 ? 65 THR H CB 1 +ATOM 13822 O OG1 . THR H 1 65 ? 57.202 -28.258 26.004 1.00 163.37 ? 65 THR H OG1 1 +ATOM 13823 C CG2 . THR H 1 65 ? 58.626 -26.361 25.468 1.00 125.34 ? 65 THR H CG2 1 +ATOM 13824 N N . ALA H 1 66 ? 61.225 -29.180 26.030 1.00 112.59 ? 66 ALA H N 1 +ATOM 13825 C CA . ALA H 1 66 ? 62.621 -29.053 26.352 1.00 90.14 ? 66 ALA H CA 1 +ATOM 13826 C C . ALA H 1 66 ? 63.473 -29.851 25.352 1.00 109.07 ? 66 ALA H C 1 +ATOM 13827 O O . ALA H 1 66 ? 64.593 -29.437 25.005 1.00 166.21 ? 66 ALA H O 1 +ATOM 13828 C CB . ALA H 1 66 ? 62.851 -29.514 27.768 1.00 86.72 ? 66 ALA H CB 1 +ATOM 13829 N N . MET H 1 67 ? 62.940 -30.985 24.885 1.00 114.34 ? 67 MET H N 1 +ATOM 13830 C CA . MET H 1 67 ? 63.628 -31.816 23.883 1.00 113.42 ? 67 MET H CA 1 +ATOM 13831 C C . MET H 1 67 ? 63.777 -31.055 22.566 1.00 117.83 ? 67 MET H C 1 +ATOM 13832 O O . MET H 1 67 ? 64.852 -31.057 21.944 1.00 105.98 ? 67 MET H O 1 +ATOM 13833 C CB . MET H 1 67 ? 62.862 -33.106 23.609 1.00 101.90 ? 67 MET H CB 1 +ATOM 13834 C CG . MET H 1 67 ? 62.871 -34.120 24.735 1.00 100.35 ? 67 MET H CG 1 +ATOM 13835 S SD . MET H 1 67 ? 61.668 -35.435 24.434 1.00 111.29 ? 67 MET H SD 1 +ATOM 13836 C CE . MET H 1 67 ? 62.030 -36.560 25.790 1.00 94.91 ? 67 MET H CE 1 +ATOM 13837 N N . LEU H 1 68 ? 62.720 -30.338 22.187 1.00 113.55 ? 68 LEU H N 1 +ATOM 13838 C CA . LEU H 1 68 ? 62.780 -29.526 20.983 1.00 135.98 ? 68 LEU H CA 1 +ATOM 13839 C C . LEU H 1 68 ? 63.810 -28.409 21.111 1.00 149.55 ? 68 LEU H C 1 +ATOM 13840 O O . LEU H 1 68 ? 64.567 -28.161 20.179 1.00 118.02 ? 68 LEU H O 1 +ATOM 13841 C CB . LEU H 1 68 ? 61.422 -28.906 20.653 1.00 147.46 ? 68 LEU H CB 1 +ATOM 13842 C CG . LEU H 1 68 ? 61.482 -27.873 19.504 1.00 138.32 ? 68 LEU H CG 1 +ATOM 13843 C CD1 . LEU H 1 68 ? 61.856 -28.545 18.193 1.00 125.82 ? 68 LEU H CD1 1 +ATOM 13844 C CD2 . LEU H 1 68 ? 60.178 -27.101 19.348 1.00 122.24 ? 68 LEU H CD2 1 +ATOM 13845 N N . VAL H 1 69 ? 63.800 -27.698 22.242 1.00 138.44 ? 69 VAL H N 1 +ATOM 13846 C CA . VAL H 1 69 ? 64.748 -26.597 22.447 1.00 113.49 ? 69 VAL H CA 1 +ATOM 13847 C C . VAL H 1 69 ? 66.166 -27.151 22.349 1.00 143.86 ? 69 VAL H C 1 +ATOM 13848 O O . VAL H 1 69 ? 67.044 -26.550 21.733 1.00 195.43 ? 69 VAL H O 1 +ATOM 13849 C CB . VAL H 1 69 ? 64.565 -25.901 23.811 1.00 100.18 ? 69 VAL H CB 1 +ATOM 13850 C CG1 . VAL H 1 69 ? 65.686 -24.905 24.044 1.00 100.27 ? 69 VAL H CG1 1 +ATOM 13851 C CG2 . VAL H 1 69 ? 63.231 -25.182 23.898 1.00 99.65 ? 69 VAL H CG2 1 +ATOM 13852 N N . THR H 1 70 ? 66.386 -28.303 22.981 1.00 146.91 ? 70 THR H N 1 +ATOM 13853 C CA . THR H 1 70 ? 67.698 -28.945 22.985 1.00 112.15 ? 70 THR H CA 1 +ATOM 13854 C C . THR H 1 70 ? 68.109 -29.348 21.575 1.00 88.61 ? 70 THR H C 1 +ATOM 13855 O O . THR H 1 70 ? 69.257 -29.095 21.158 1.00 79.16 ? 70 THR H O 1 +ATOM 13856 C CB . THR H 1 70 ? 67.709 -30.168 23.910 1.00 100.86 ? 70 THR H CB 1 +ATOM 13857 O OG1 . THR H 1 70 ? 67.297 -29.750 25.220 1.00 100.86 ? 70 THR H OG1 1 +ATOM 13858 C CG2 . THR H 1 70 ? 69.112 -30.789 23.981 1.00 118.23 ? 70 THR H CG2 1 +ATOM 13859 N N . ALA H 1 71 ? 67.177 -29.938 20.838 1.00 75.17 ? 71 ALA H N 1 +ATOM 13860 C CA . ALA H 1 71 ? 67.455 -30.301 19.455 1.00 107.25 ? 71 ALA H CA 1 +ATOM 13861 C C . ALA H 1 71 ? 67.763 -29.071 18.591 1.00 96.61 ? 71 ALA H C 1 +ATOM 13862 O O . ALA H 1 71 ? 68.712 -29.085 17.769 1.00 89.85 ? 71 ALA H O 1 +ATOM 13863 C CB . ALA H 1 71 ? 66.289 -31.069 18.864 1.00 129.18 ? 71 ALA H CB 1 +ATOM 13864 N N . LEU H 1 72 ? 67.001 -28.000 18.805 1.00 80.14 ? 72 LEU H N 1 +ATOM 13865 C CA . LEU H 1 72 ? 67.248 -26.729 18.098 1.00 102.91 ? 72 LEU H CA 1 +ATOM 13866 C C . LEU H 1 72 ? 68.629 -26.148 18.408 1.00 126.59 ? 72 LEU H C 1 +ATOM 13867 O O . LEU H 1 72 ? 69.223 -25.458 17.580 1.00 101.04 ? 72 LEU H O 1 +ATOM 13868 C CB . LEU H 1 72 ? 66.203 -25.680 18.454 1.00 80.53 ? 72 LEU H CB 1 +ATOM 13869 C CG . LEU H 1 72 ? 64.811 -25.990 17.959 1.00 80.96 ? 72 LEU H CG 1 +ATOM 13870 C CD1 . LEU H 1 72 ? 63.825 -25.132 18.706 1.00 75.44 ? 72 LEU H CD1 1 +ATOM 13871 C CD2 . LEU H 1 72 ? 64.678 -25.756 16.463 1.00 97.77 ? 72 LEU H CD2 1 +ATOM 13872 N N . LYS H 1 73 ? 69.168 -26.482 19.579 1.00 136.53 ? 73 LYS H N 1 +ATOM 13873 C CA . LYS H 1 73 ? 70.505 -26.021 19.943 1.00 126.15 ? 73 LYS H CA 1 +ATOM 13874 C C . LYS H 1 73 ? 71.594 -26.914 19.360 1.00 112.36 ? 73 LYS H C 1 +ATOM 13875 O O . LYS H 1 73 ? 72.584 -26.410 18.833 1.00 103.45 ? 73 LYS H O 1 +ATOM 13876 C CB . LYS H 1 73 ? 70.674 -25.940 21.463 1.00 146.47 ? 73 LYS H CB 1 +ATOM 13877 C CG . LYS H 1 73 ? 71.923 -25.169 21.905 1.00 156.15 ? 73 LYS H CG 1 +ATOM 13878 C CD . LYS H 1 73 ? 72.059 -25.115 23.431 1.00 150.94 ? 73 LYS H CD 1 +ATOM 13879 C CE . LYS H 1 73 ? 73.514 -25.001 23.872 1.00 149.87 ? 73 LYS H CE 1 +ATOM 13880 N NZ . LYS H 1 73 ? 73.838 -23.705 24.524 1.00 143.27 ? 73 LYS H NZ 1 +ATOM 13881 N N . ASP H 1 74 ? 71.437 -28.228 19.511 1.00 95.80 ? 74 ASP H N 1 +ATOM 13882 C CA . ASP H 1 74 ? 72.459 -29.178 19.069 1.00 100.95 ? 74 ASP H CA 1 +ATOM 13883 C C . ASP H 1 74 ? 72.737 -29.030 17.579 1.00 93.22 ? 74 ASP H C 1 +ATOM 13884 O O . ASP H 1 74 ? 73.836 -29.343 17.115 1.00 112.49 ? 74 ASP H O 1 +ATOM 13885 C CB . ASP H 1 74 ? 72.042 -30.617 19.398 1.00 102.59 ? 74 ASP H CB 1 +ATOM 13886 C CG . ASP H 1 74 ? 72.058 -30.918 20.903 1.00 112.74 ? 74 ASP H CG 1 +ATOM 13887 O OD1 . ASP H 1 74 ? 72.823 -30.273 21.670 1.00 82.37 ? 74 ASP H OD1 1 +ATOM 13888 O OD2 . ASP H 1 74 ? 71.247 -31.789 21.314 1.00 111.07 ? 74 ASP H OD2 1 +ATOM 13889 N N . SER H 1 75 ? 71.724 -28.601 16.825 1.00 98.26 ? 75 SER H N 1 +ATOM 13890 C CA . SER H 1 75 ? 71.821 -28.502 15.362 1.00 131.01 ? 75 SER H CA 1 +ATOM 13891 C C . SER H 1 75 ? 72.867 -27.478 14.924 1.00 132.25 ? 75 SER H C 1 +ATOM 13892 O O . SER H 1 75 ? 73.379 -27.545 13.798 1.00 127.34 ? 75 SER H O 1 +ATOM 13893 C CB . SER H 1 75 ? 70.461 -28.137 14.745 1.00 142.29 ? 75 SER H CB 1 +ATOM 13894 O OG . SER H 1 75 ? 70.254 -26.731 14.751 1.00 140.41 ? 75 SER H OG 1 +ATOM 13895 N N . ARG H 1 76 ? 73.139 -26.518 15.803 1.00 120.28 ? 76 ARG H N 1 +ATOM 13896 C CA . ARG H 1 76 ? 74.038 -25.407 15.511 1.00 146.79 ? 76 ARG H CA 1 +ATOM 13897 C C . ARG H 1 76 ? 73.534 -24.581 14.336 1.00 146.01 ? 76 ARG H C 1 +ATOM 13898 O O . ARG H 1 76 ? 74.314 -24.028 13.567 1.00 145.94 ? 76 ARG H O 1 +ATOM 13899 C CB . ARG H 1 76 ? 75.453 -25.898 15.240 1.00 156.26 ? 76 ARG H CB 1 +ATOM 13900 C CG . ARG H 1 76 ? 76.092 -26.661 16.396 1.00 156.27 ? 76 ARG H CG 1 +ATOM 13901 C CD . ARG H 1 76 ? 77.510 -27.076 16.033 1.00 139.18 ? 76 ARG H CD 1 +ATOM 13902 N NE . ARG H 1 76 ? 77.522 -28.106 14.996 1.00 149.04 ? 76 ARG H NE 1 +ATOM 13903 C CZ . ARG H 1 76 ? 77.627 -27.880 13.685 1.00 167.73 ? 76 ARG H CZ 1 +ATOM 13904 N NH1 . ARG H 1 76 ? 77.735 -26.646 13.194 1.00 160.04 ? 76 ARG H NH1 1 +ATOM 13905 N NH2 . ARG H 1 76 ? 77.616 -28.910 12.851 1.00 181.17 ? 76 ARG H NH2 1 +ATOM 13906 N N . TRP H 1 77 ? 72.216 -24.432 14.278 1.00 147.87 ? 77 TRP H N 1 +ATOM 13907 C CA . TRP H 1 77 ? 71.562 -23.483 13.389 1.00 139.18 ? 77 TRP H CA 1 +ATOM 13908 C C . TRP H 1 77 ? 70.832 -22.365 14.172 1.00 149.03 ? 77 TRP H C 1 +ATOM 13909 O O . TRP H 1 77 ? 70.743 -21.226 13.708 1.00 102.13 ? 77 TRP H O 1 +ATOM 13910 C CB . TRP H 1 77 ? 70.564 -24.242 12.524 1.00 130.96 ? 77 TRP H CB 1 +ATOM 13911 C CG . TRP H 1 77 ? 71.127 -24.724 11.246 1.00 117.71 ? 77 TRP H CG 1 +ATOM 13912 C CD1 . TRP H 1 77 ? 71.919 -25.814 11.057 1.00 108.25 ? 77 TRP H CD1 1 +ATOM 13913 C CD2 . TRP H 1 77 ? 70.875 -24.176 9.952 1.00 109.79 ? 77 TRP H CD2 1 +ATOM 13914 N NE1 . TRP H 1 77 ? 72.168 -25.986 9.724 1.00 113.75 ? 77 TRP H NE1 1 +ATOM 13915 C CE2 . TRP H 1 77 ? 71.556 -24.974 9.028 1.00 108.47 ? 77 TRP H CE2 1 +ATOM 13916 C CE3 . TRP H 1 77 ? 70.130 -23.086 9.484 1.00 118.24 ? 77 TRP H CE3 1 +ATOM 13917 C CZ2 . TRP H 1 77 ? 71.541 -24.704 7.664 1.00 122.86 ? 77 TRP H CZ2 1 +ATOM 13918 C CZ3 . TRP H 1 77 ? 70.117 -22.820 8.126 1.00 109.05 ? 77 TRP H CZ3 1 +ATOM 13919 C CH2 . TRP H 1 77 ? 70.812 -23.625 7.235 1.00 112.19 ? 77 TRP H CH2 1 +ATOM 13920 N N . PHE H 1 78 ? 70.307 -22.720 15.352 1.00 148.06 ? 78 PHE H N 1 +ATOM 13921 C CA . PHE H 1 78 ? 69.451 -21.841 16.161 1.00 99.82 ? 78 PHE H CA 1 +ATOM 13922 C C . PHE H 1 78 ? 69.989 -21.579 17.563 1.00 84.34 ? 78 PHE H C 1 +ATOM 13923 O O . PHE H 1 78 ? 70.598 -22.447 18.183 1.00 59.19 ? 78 PHE H O 1 +ATOM 13924 C CB . PHE H 1 78 ? 68.108 -22.490 16.358 1.00 97.47 ? 78 PHE H CB 1 +ATOM 13925 C CG . PHE H 1 78 ? 67.439 -22.876 15.087 1.00 100.61 ? 78 PHE H CG 1 +ATOM 13926 C CD1 . PHE H 1 78 ? 66.878 -21.901 14.253 1.00 89.91 ? 78 PHE H CD1 1 +ATOM 13927 C CD2 . PHE H 1 78 ? 67.347 -24.213 14.733 1.00 78.64 ? 78 PHE H CD2 1 +ATOM 13928 C CE1 . PHE H 1 78 ? 66.235 -22.263 13.096 1.00 114.57 ? 78 PHE H CE1 1 +ATOM 13929 C CE2 . PHE H 1 78 ? 66.719 -24.580 13.568 1.00 101.12 ? 78 PHE H CE2 1 +ATOM 13930 C CZ . PHE H 1 78 ? 66.160 -23.605 12.744 1.00 130.01 ? 78 PHE H CZ 1 +ATOM 13931 N N . ILE H 1 79 ? 69.807 -20.342 18.023 1.00 102.58 ? 79 ILE H N 1 +ATOM 13932 C CA . ILE H 1 79 ? 69.989 -19.963 19.436 1.00 89.78 ? 79 ILE H CA 1 +ATOM 13933 C C . ILE H 1 79 ? 68.593 -19.950 20.036 1.00 85.79 ? 79 ILE H C 1 +ATOM 13934 O O . ILE H 1 79 ? 67.701 -19.293 19.486 1.00 63.43 ? 79 ILE H O 1 +ATOM 13935 C CB . ILE H 1 79 ? 70.566 -18.541 19.589 1.00 85.02 ? 79 ILE H CB 1 +ATOM 13936 C CG1 . ILE H 1 79 ? 71.803 -18.354 18.708 1.00 97.48 ? 79 ILE H CG1 1 +ATOM 13937 C CG2 . ILE H 1 79 ? 70.909 -18.248 21.039 1.00 73.18 ? 79 ILE H CG2 1 +ATOM 13938 C CD1 . ILE H 1 79 ? 72.099 -16.902 18.351 1.00 87.56 ? 79 ILE H CD1 1 +ATOM 13939 N N . PRO H 1 80 ? 68.376 -20.765 21.080 1.00 83.38 ? 80 PRO H N 1 +ATOM 13940 C CA . PRO H 1 80 ? 67.069 -20.751 21.654 1.00 69.92 ? 80 PRO H CA 1 +ATOM 13941 C C . PRO H 1 80 ? 66.985 -19.714 22.742 1.00 74.73 ? 80 PRO H C 1 +ATOM 13942 O O . PRO H 1 80 ? 67.899 -19.605 23.542 1.00 57.36 ? 80 PRO H O 1 +ATOM 13943 C CB . PRO H 1 80 ? 66.916 -22.159 22.230 1.00 57.63 ? 80 PRO H CB 1 +ATOM 13944 C CG . PRO H 1 80 ? 67.841 -22.976 21.440 1.00 77.89 ? 80 PRO H CG 1 +ATOM 13945 C CD . PRO H 1 80 ? 69.025 -22.070 21.284 1.00 97.04 ? 80 PRO H CD 1 +ATOM 13946 N N . LEU H 1 81 ? 65.934 -18.888 22.679 1.00 77.75 ? 81 LEU H N 1 +ATOM 13947 C CA . LEU H 1 81 ? 65.633 -17.926 23.716 1.00 58.93 ? 81 LEU H CA 1 +ATOM 13948 C C . LEU H 1 81 ? 64.637 -18.498 24.679 1.00 70.37 ? 81 LEU H C 1 +ATOM 13949 O O . LEU H 1 81 ? 63.798 -19.346 24.296 1.00 81.24 ? 81 LEU H O 1 +ATOM 13950 C CB . LEU H 1 81 ? 65.079 -16.691 23.113 1.00 59.66 ? 81 LEU H CB 1 +ATOM 13951 C CG . LEU H 1 81 ? 66.001 -16.124 22.035 1.00 94.72 ? 81 LEU H CG 1 +ATOM 13952 C CD1 . LEU H 1 81 ? 65.330 -14.936 21.398 1.00 88.92 ? 81 LEU H CD1 1 +ATOM 13953 C CD2 . LEU H 1 81 ? 67.334 -15.709 22.632 1.00 133.47 ? 81 LEU H CD2 1 +ATOM 13954 N N . GLU H 1 82 ? 64.915 -18.255 25.960 1.00 102.13 ? 82 GLU H N 1 +ATOM 13955 C CA . GLU H 1 82 ? 64.221 -18.956 27.060 1.00 109.93 ? 82 GLU H CA 1 +ATOM 13956 C C . GLU H 1 82 ? 62.891 -18.305 27.312 1.00 95.65 ? 82 GLU H C 1 +ATOM 13957 O O . GLU H 1 82 ? 62.824 -17.155 27.745 1.00 60.38 ? 82 GLU H O 1 +ATOM 13958 C CB . GLU H 1 82 ? 65.043 -18.986 28.362 1.00 113.53 ? 82 GLU H CB 1 +ATOM 13959 C CG . GLU H 1 82 ? 64.319 -19.624 29.557 1.00 91.76 ? 82 GLU H CG 1 +ATOM 13960 C CD . GLU H 1 82 ? 64.125 -21.162 29.461 1.00 82.73 ? 82 GLU H CD 1 +ATOM 13961 O OE1 . GLU H 1 82 ? 63.695 -21.698 28.424 1.00 74.33 ? 82 GLU H OE1 1 +ATOM 13962 O OE2 . GLU H 1 82 ? 64.411 -21.868 30.446 1.00 54.39 ? 82 GLU H OE2 1 +ATOM 13963 N N . ARG H 1 83 ? 61.845 -19.044 26.934 1.00 100.02 ? 83 ARG H N 1 +ATOM 13964 C CA . ARG H 1 83 ? 60.472 -18.624 27.151 1.00 72.80 ? 83 ARG H CA 1 +ATOM 13965 C C . ARG H 1 83 ? 59.682 -19.648 27.973 1.00 64.97 ? 83 ARG H C 1 +ATOM 13966 O O . ARG H 1 83 ? 58.684 -19.289 28.589 1.00 56.35 ? 83 ARG H O 1 +ATOM 13967 C CB . ARG H 1 83 ? 59.773 -18.344 25.825 1.00 50.65 ? 83 ARG H CB 1 +ATOM 13968 C CG . ARG H 1 83 ? 60.467 -17.326 24.956 1.00 36.43 ? 83 ARG H CG 1 +ATOM 13969 C CD . ARG H 1 83 ? 60.416 -15.968 25.504 1.00 29.69 ? 83 ARG H CD 1 +ATOM 13970 N NE . ARG H 1 83 ? 60.889 -15.105 24.432 1.00 38.66 ? 83 ARG H NE 1 +ATOM 13971 C CZ . ARG H 1 83 ? 62.060 -14.487 24.426 1.00 71.26 ? 83 ARG H CZ 1 +ATOM 13972 N NH1 . ARG H 1 83 ? 62.943 -14.649 25.432 1.00 88.81 ? 83 ARG H NH1 1 +ATOM 13973 N NH2 . ARG H 1 83 ? 62.389 -13.703 23.386 1.00 84.82 ? 83 ARG H NH2 1 +ATOM 13974 N N . GLN H 1 84 ? 60.139 -20.894 28.051 1.00 70.61 ? 84 GLN H N 1 +ATOM 13975 C CA . GLN H 1 84 ? 59.413 -21.870 28.888 1.00 110.37 ? 84 GLN H CA 1 +ATOM 13976 C C . GLN H 1 84 ? 59.346 -21.398 30.340 1.00 97.25 ? 84 GLN H C 1 +ATOM 13977 O O . GLN H 1 84 ? 58.308 -21.471 30.974 1.00 118.31 ? 84 GLN H O 1 +ATOM 13978 C CB . GLN H 1 84 ? 60.001 -23.293 28.810 1.00 117.20 ? 84 GLN H CB 1 +ATOM 13979 C CG . GLN H 1 84 ? 58.974 -24.418 28.979 1.00 100.04 ? 84 GLN H CG 1 +ATOM 13980 C CD . GLN H 1 84 ? 59.630 -25.793 29.013 1.00 107.21 ? 84 GLN H CD 1 +ATOM 13981 O OE1 . GLN H 1 84 ? 60.583 -26.060 28.281 1.00 81.30 ? 84 GLN H OE1 1 +ATOM 13982 N NE2 . GLN H 1 84 ? 59.074 -26.693 29.817 1.00 134.06 ? 84 GLN H NE2 1 +ATOM 13983 N N . GLY H 1 85 ? 60.425 -20.846 30.850 1.00 81.88 ? 85 GLY H N 1 +ATOM 13984 C CA . GLY H 1 85 ? 60.378 -20.334 32.209 1.00 84.09 ? 85 GLY H CA 1 +ATOM 13985 C C . GLY H 1 85 ? 60.415 -18.818 32.287 1.00 80.39 ? 85 GLY H C 1 +ATOM 13986 O O . GLY H 1 85 ? 61.105 -18.269 33.154 1.00 90.92 ? 85 GLY H O 1 +ATOM 13987 N N . LEU H 1 86 ? 59.720 -18.136 31.369 1.00 66.02 ? 86 LEU H N 1 +ATOM 13988 C CA . LEU H 1 86 ? 59.925 -16.692 31.166 1.00 64.97 ? 86 LEU H CA 1 +ATOM 13989 C C . LEU H 1 86 ? 59.642 -15.897 32.434 1.00 73.92 ? 86 LEU H C 1 +ATOM 13990 O O . LEU H 1 86 ? 60.335 -14.910 32.733 1.00 70.66 ? 86 LEU H O 1 +ATOM 13991 C CB . LEU H 1 86 ? 59.040 -16.161 30.047 1.00 62.67 ? 86 LEU H CB 1 +ATOM 13992 C CG . LEU H 1 86 ? 58.962 -14.637 29.793 1.00 66.71 ? 86 LEU H CG 1 +ATOM 13993 C CD1 . LEU H 1 86 ? 60.291 -14.003 29.447 1.00 53.68 ? 86 LEU H CD1 1 +ATOM 13994 C CD2 . LEU H 1 86 ? 57.957 -14.376 28.663 1.00 84.68 ? 86 LEU H CD2 1 +ATOM 13995 N N . GLN H 1 87 ? 58.701 -16.387 33.229 1.00 75.40 ? 87 GLN H N 1 +ATOM 13996 C CA . GLN H 1 87 ? 58.308 -15.667 34.420 1.00 93.52 ? 87 GLN H CA 1 +ATOM 13997 C C . GLN H 1 87 ? 59.490 -15.517 35.410 1.00 95.78 ? 87 GLN H C 1 +ATOM 13998 O O . GLN H 1 87 ? 59.711 -14.434 36.004 1.00 71.01 ? 87 GLN H O 1 +ATOM 13999 C CB . GLN H 1 87 ? 57.090 -16.351 35.060 1.00 105.50 ? 87 GLN H CB 1 +ATOM 14000 C CG . GLN H 1 87 ? 56.108 -15.381 35.723 1.00 118.01 ? 87 GLN H CG 1 +ATOM 14001 C CD . GLN H 1 87 ? 55.829 -14.115 34.899 1.00 122.26 ? 87 GLN H CD 1 +ATOM 14002 O OE1 . GLN H 1 87 ? 55.414 -14.185 33.737 1.00 83.08 ? 87 GLN H OE1 1 +ATOM 14003 N NE2 . GLN H 1 87 ? 56.066 -12.951 35.501 1.00 130.79 ? 87 GLN H NE2 1 +ATOM 14004 N N . ASN H 1 88 ? 60.241 -16.606 35.600 1.00 92.72 ? 88 ASN H N 1 +ATOM 14005 C CA . ASN H 1 88 ? 61.387 -16.608 36.537 1.00 86.81 ? 88 ASN H CA 1 +ATOM 14006 C C . ASN H 1 88 ? 62.493 -15.686 36.061 1.00 74.60 ? 88 ASN H C 1 +ATOM 14007 O O . ASN H 1 88 ? 63.190 -15.052 36.837 1.00 57.28 ? 88 ASN H O 1 +ATOM 14008 C CB . ASN H 1 88 ? 61.959 -18.001 36.652 1.00 88.36 ? 88 ASN H CB 1 +ATOM 14009 C CG . ASN H 1 88 ? 60.937 -18.991 37.079 1.00 107.70 ? 88 ASN H CG 1 +ATOM 14010 O OD1 . ASN H 1 88 ? 60.098 -18.684 37.937 1.00 140.18 ? 88 ASN H OD1 1 +ATOM 14011 N ND2 . ASN H 1 88 ? 60.989 -20.196 36.510 1.00 119.36 ? 88 ASN H ND2 1 +ATOM 14012 N N . LEU H 1 89 ? 62.623 -15.615 34.748 1.00 72.99 ? 89 LEU H N 1 +ATOM 14013 C CA . LEU H 1 89 ? 63.646 -14.821 34.132 1.00 73.76 ? 89 LEU H CA 1 +ATOM 14014 C C . LEU H 1 89 ? 63.337 -13.365 34.469 1.00 68.44 ? 89 LEU H C 1 +ATOM 14015 O O . LEU H 1 89 ? 64.237 -12.580 34.808 1.00 73.66 ? 89 LEU H O 1 +ATOM 14016 C CB . LEU H 1 89 ? 63.643 -15.104 32.613 1.00 99.41 ? 89 LEU H CB 1 +ATOM 14017 C CG . LEU H 1 89 ? 64.940 -14.976 31.815 1.00 109.09 ? 89 LEU H CG 1 +ATOM 14018 C CD1 . LEU H 1 89 ? 64.802 -13.845 30.814 1.00 123.99 ? 89 LEU H CD1 1 +ATOM 14019 C CD2 . LEU H 1 89 ? 66.135 -14.736 32.716 1.00 108.32 ? 89 LEU H CD2 1 +ATOM 14020 N N . LEU H 1 90 ? 62.059 -13.007 34.372 1.00 70.32 ? 90 LEU H N 1 +ATOM 14021 C CA . LEU H 1 90 ? 61.652 -11.611 34.564 1.00 71.59 ? 90 LEU H CA 1 +ATOM 14022 C C . LEU H 1 90 ? 61.775 -11.239 36.038 1.00 74.32 ? 90 LEU H C 1 +ATOM 14023 O O . LEU H 1 90 ? 62.041 -10.094 36.387 1.00 64.81 ? 90 LEU H O 1 +ATOM 14024 C CB . LEU H 1 90 ? 60.225 -11.420 34.081 1.00 65.10 ? 90 LEU H CB 1 +ATOM 14025 C CG . LEU H 1 90 ? 60.001 -11.697 32.606 1.00 67.23 ? 90 LEU H CG 1 +ATOM 14026 C CD1 . LEU H 1 90 ? 58.535 -11.917 32.330 1.00 65.74 ? 90 LEU H CD1 1 +ATOM 14027 C CD2 . LEU H 1 90 ? 60.543 -10.520 31.805 1.00 85.73 ? 90 LEU H CD2 1 +ATOM 14028 N N . ASN H 1 91 ? 61.586 -12.238 36.897 1.00 76.12 ? 91 ASN H N 1 +ATOM 14029 C CA . ASN H 1 91 ? 61.710 -12.064 38.342 1.00 68.42 ? 91 ASN H CA 1 +ATOM 14030 C C . ASN H 1 91 ? 63.154 -11.822 38.775 1.00 61.65 ? 91 ASN H C 1 +ATOM 14031 O O . ASN H 1 91 ? 63.439 -10.856 39.467 1.00 58.38 ? 91 ASN H O 1 +ATOM 14032 C CB . ASN H 1 91 ? 61.188 -13.317 39.026 1.00 91.46 ? 91 ASN H CB 1 +ATOM 14033 C CG . ASN H 1 91 ? 59.979 -13.090 39.887 1.00 106.63 ? 91 ASN H CG 1 +ATOM 14034 O OD1 . ASN H 1 91 ? 59.217 -12.146 39.712 1.00 106.26 ? 91 ASN H OD1 1 +ATOM 14035 N ND2 . ASN H 1 91 ? 59.769 -14.028 40.797 1.00 138.23 ? 91 ASN H ND2 1 +ATOM 14036 N N . GLU H 1 92 ? 64.082 -12.644 38.284 1.00 64.20 ? 92 GLU H N 1 +ATOM 14037 C CA . GLU H 1 92 ? 65.527 -12.385 38.509 1.00 70.07 ? 92 GLU H CA 1 +ATOM 14038 C C . GLU H 1 92 ? 65.985 -11.007 37.999 1.00 70.10 ? 92 GLU H C 1 +ATOM 14039 O O . GLU H 1 92 ? 66.778 -10.320 38.646 1.00 72.96 ? 92 GLU H O 1 +ATOM 14040 C CB . GLU H 1 92 ? 66.422 -13.453 37.859 1.00 60.01 ? 92 GLU H CB 1 +ATOM 14041 C CG . GLU H 1 92 ? 66.726 -14.661 38.733 1.00 47.32 ? 92 GLU H CG 1 +ATOM 14042 C CD . GLU H 1 92 ? 67.307 -14.334 40.099 1.00 41.18 ? 92 GLU H CD 1 +ATOM 14043 O OE1 . GLU H 1 92 ? 68.330 -13.617 40.191 1.00 48.44 ? 92 GLU H OE1 1 +ATOM 14044 O OE2 . GLU H 1 92 ? 66.661 -14.682 41.115 1.00 37.43 ? 92 GLU H OE2 1 +ATOM 14045 N N . ARG H 1 93 ? 65.405 -10.576 36.887 1.00 66.54 ? 93 ARG H N 1 +ATOM 14046 C CA . ARG H 1 93 ? 65.672 -9.251 36.366 1.00 71.54 ? 93 ARG H CA 1 +ATOM 14047 C C . ARG H 1 93 ? 65.065 -8.130 37.248 1.00 70.13 ? 93 ARG H C 1 +ATOM 14048 O O . ARG H 1 93 ? 65.675 -7.078 37.440 1.00 51.30 ? 93 ARG H O 1 +ATOM 14049 C CB . ARG H 1 93 ? 65.210 -9.168 34.904 1.00 73.92 ? 93 ARG H CB 1 +ATOM 14050 C CG . ARG H 1 93 ? 66.065 -10.049 33.972 1.00 74.60 ? 93 ARG H CG 1 +ATOM 14051 C CD . ARG H 1 93 ? 65.468 -10.310 32.573 1.00 55.06 ? 93 ARG H CD 1 +ATOM 14052 N NE . ARG H 1 93 ? 66.063 -9.535 31.493 1.00 40.34 ? 93 ARG H NE 1 +ATOM 14053 C CZ . ARG H 1 93 ? 65.621 -8.346 31.132 1.00 56.41 ? 93 ARG H CZ 1 +ATOM 14054 N NH1 . ARG H 1 93 ? 64.492 -7.810 31.658 1.00 105.13 ? 93 ARG H NH1 1 +ATOM 14055 N NH2 . ARG H 1 93 ? 66.215 -7.718 30.161 1.00 56.70 ? 93 ARG H NH2 1 +ATOM 14056 N N . LYS H 1 94 ? 63.923 -8.390 37.869 1.00 84.47 ? 94 LYS H N 1 +ATOM 14057 C CA . LYS H 1 94 ? 63.398 -7.458 38.870 1.00 90.44 ? 94 LYS H CA 1 +ATOM 14058 C C . LYS H 1 94 ? 64.377 -7.323 40.037 1.00 74.95 ? 94 LYS H C 1 +ATOM 14059 O O . LYS H 1 94 ? 64.562 -6.224 40.575 1.00 59.19 ? 94 LYS H O 1 +ATOM 14060 C CB . LYS H 1 94 ? 62.038 -7.931 39.396 1.00 101.73 ? 94 LYS H CB 1 +ATOM 14061 C CG . LYS H 1 94 ? 60.838 -7.474 38.584 1.00 112.79 ? 94 LYS H CG 1 +ATOM 14062 C CD . LYS H 1 94 ? 59.577 -8.166 39.081 1.00 133.73 ? 94 LYS H CD 1 +ATOM 14063 C CE . LYS H 1 94 ? 58.298 -7.440 38.678 1.00 142.55 ? 94 LYS H CE 1 +ATOM 14064 N NZ . LYS H 1 94 ? 57.116 -8.324 38.878 1.00 143.51 ? 94 LYS H NZ 1 +ATOM 14065 N N . ILE H 1 95 ? 64.932 -8.457 40.471 1.00 69.43 ? 95 ILE H N 1 +ATOM 14066 C CA . ILE H 1 95 ? 65.768 -8.474 41.671 1.00 91.72 ? 95 ILE H CA 1 +ATOM 14067 C C . ILE H 1 95 ? 67.086 -7.788 41.412 1.00 86.94 ? 95 ILE H C 1 +ATOM 14068 O O . ILE H 1 95 ? 67.586 -7.025 42.284 1.00 120.23 ? 95 ILE H O 1 +ATOM 14069 C CB . ILE H 1 95 ? 66.077 -9.890 42.203 1.00 102.05 ? 95 ILE H CB 1 +ATOM 14070 C CG1 . ILE H 1 95 ? 64.790 -10.729 42.312 1.00 92.87 ? 95 ILE H CG1 1 +ATOM 14071 C CG2 . ILE H 1 95 ? 66.704 -9.750 43.582 1.00 100.78 ? 95 ILE H CG2 1 +ATOM 14072 C CD1 . ILE H 1 95 ? 64.930 -11.996 43.121 1.00 84.19 ? 95 ILE H CD1 1 +ATOM 14073 N N . ILE H 1 96 ? 67.630 -8.059 40.225 1.00 64.72 ? 96 ILE H N 1 +ATOM 14074 C CA . ILE H 1 96 ? 68.748 -7.301 39.725 1.00 65.42 ? 96 ILE H CA 1 +ATOM 14075 C C . ILE H 1 96 ? 68.471 -5.788 39.776 1.00 70.34 ? 96 ILE H C 1 +ATOM 14076 O O . ILE H 1 96 ? 69.210 -5.035 40.417 1.00 80.55 ? 96 ILE H O 1 +ATOM 14077 C CB . ILE H 1 96 ? 69.124 -7.684 38.289 1.00 67.23 ? 96 ILE H CB 1 +ATOM 14078 C CG1 . ILE H 1 96 ? 69.599 -9.119 38.253 1.00 73.50 ? 96 ILE H CG1 1 +ATOM 14079 C CG2 . ILE H 1 96 ? 70.243 -6.781 37.776 1.00 67.52 ? 96 ILE H CG2 1 +ATOM 14080 C CD1 . ILE H 1 96 ? 70.060 -9.553 36.872 1.00 88.61 ? 96 ILE H CD1 1 +ATOM 14081 N N . ARG H 1 97 ? 67.447 -5.343 39.070 1.00 79.74 ? 97 ARG H N 1 +ATOM 14082 C CA . ARG H 1 97 ? 67.188 -3.915 38.946 1.00 93.41 ? 97 ARG H CA 1 +ATOM 14083 C C . ARG H 1 97 ? 66.989 -3.297 40.326 1.00 88.45 ? 97 ARG H C 1 +ATOM 14084 O O . ARG H 1 97 ? 67.231 -2.099 40.522 1.00 90.84 ? 97 ARG H O 1 +ATOM 14085 C CB . ARG H 1 97 ? 65.966 -3.656 38.040 1.00 97.62 ? 97 ARG H CB 1 +ATOM 14086 C CG . ARG H 1 97 ? 66.304 -3.164 36.636 1.00 100.79 ? 97 ARG H CG 1 +ATOM 14087 C CD . ARG H 1 97 ? 65.044 -2.858 35.823 1.00 110.22 ? 97 ARG H CD 1 +ATOM 14088 N NE . ARG H 1 97 ? 64.438 -4.049 35.237 1.00 111.98 ? 97 ARG H NE 1 +ATOM 14089 C CZ . ARG H 1 97 ? 64.637 -4.464 33.987 1.00 125.10 ? 97 ARG H CZ 1 +ATOM 14090 N NH1 . ARG H 1 97 ? 65.417 -3.781 33.143 1.00 119.72 ? 97 ARG H NH1 1 +ATOM 14091 N NH2 . ARG H 1 97 ? 64.073 -5.596 33.580 1.00 137.72 ? 97 ARG H NH2 1 +ATOM 14092 N N . ALA H 1 98 ? 66.448 -4.084 41.251 1.00 72.97 ? 98 ALA H N 1 +ATOM 14093 C CA . ALA H 1 98 ? 66.166 -3.571 42.570 1.00 86.63 ? 98 ALA H CA 1 +ATOM 14094 C C . ALA H 1 98 ? 67.449 -3.465 43.358 1.00 72.47 ? 98 ALA H C 1 +ATOM 14095 O O . ALA H 1 98 ? 67.590 -2.605 44.253 1.00 66.24 ? 98 ALA H O 1 +ATOM 14096 C CB . ALA H 1 98 ? 65.174 -4.470 43.282 1.00 107.47 ? 98 ALA H CB 1 +ATOM 14097 N N . ALA H 1 99 ? 68.392 -4.319 42.997 1.00 73.77 ? 99 ALA H N 1 +ATOM 14098 C CA . ALA H 1 99 ? 69.715 -4.331 43.642 1.00 104.80 ? 99 ALA H CA 1 +ATOM 14099 C C . ALA H 1 99 ? 70.577 -3.075 43.326 1.00 82.58 ? 99 ALA H C 1 +ATOM 14100 O O . ALA H 1 99 ? 71.085 -2.415 44.218 1.00 41.76 ? 99 ALA H O 1 +ATOM 14101 C CB . ALA H 1 99 ? 70.486 -5.595 43.250 1.00 106.73 ? 99 ALA H CB 1 +ATOM 14102 N N . GLN H 1 100 ? 70.672 -2.749 42.050 1.00 76.09 ? 100 GLN H N 1 +ATOM 14103 C CA . GLN H 1 100 ? 71.681 -1.823 41.592 1.00 72.96 ? 100 GLN H CA 1 +ATOM 14104 C C . GLN H 1 100 ? 71.128 -0.468 41.198 1.00 86.16 ? 100 GLN H C 1 +ATOM 14105 O O . GLN H 1 100 ? 71.858 0.367 40.661 1.00 95.83 ? 100 GLN H O 1 +ATOM 14106 C CB . GLN H 1 100 ? 72.467 -2.441 40.428 1.00 90.71 ? 100 GLN H CB 1 +ATOM 14107 C CG . GLN H 1 100 ? 71.637 -3.184 39.384 1.00 95.47 ? 100 GLN H CG 1 +ATOM 14108 C CD . GLN H 1 100 ? 72.426 -4.286 38.669 1.00 105.09 ? 100 GLN H CD 1 +ATOM 14109 O OE1 . GLN H 1 100 ? 72.902 -5.274 39.286 1.00 63.62 ? 100 GLN H OE1 1 +ATOM 14110 N NE2 . GLN H 1 100 ? 72.498 -4.162 37.351 1.00 100.14 ? 100 GLN H NE2 1 +ATOM 14111 N N . GLU H 1 101 ? 69.839 -0.241 41.447 1.00 101.22 ? 101 GLU H N 1 +ATOM 14112 C CA . GLU H 1 101 ? 69.193 1.035 41.068 1.00 95.74 ? 101 GLU H CA 1 +ATOM 14113 C C . GLU H 1 101 ? 69.719 2.245 41.860 1.00 92.73 ? 101 GLU H C 1 +ATOM 14114 O O . GLU H 1 101 ? 69.650 3.373 41.398 1.00 57.68 ? 101 GLU H O 1 +ATOM 14115 C CB . GLU H 1 101 ? 67.670 0.942 41.208 1.00 88.04 ? 101 GLU H CB 1 +ATOM 14116 C CG . GLU H 1 101 ? 67.187 0.447 42.565 1.00 95.35 ? 101 GLU H CG 1 +ATOM 14117 C CD . GLU H 1 101 ? 65.668 0.461 42.689 1.00 101.80 ? 101 GLU H CD 1 +ATOM 14118 O OE1 . GLU H 1 101 ? 64.995 0.519 41.644 1.00 103.01 ? 101 GLU H OE1 1 +ATOM 14119 O OE2 . GLU H 1 101 ? 65.147 0.399 43.825 1.00 95.97 ? 101 GLU H OE2 1 +ATOM 14120 N N . ASN H 1 102 ? 70.282 1.995 43.037 1.00 102.78 ? 102 ASN H N 1 +ATOM 14121 C CA . ASN H 1 102 ? 70.779 3.078 43.876 1.00 96.83 ? 102 ASN H CA 1 +ATOM 14122 C C . ASN H 1 102 ? 72.254 3.399 43.670 1.00 102.74 ? 102 ASN H C 1 +ATOM 14123 O O . ASN H 1 102 ? 72.795 4.281 44.322 1.00 87.88 ? 102 ASN H O 1 +ATOM 14124 C CB . ASN H 1 102 ? 70.522 2.745 45.336 1.00 104.41 ? 102 ASN H CB 1 +ATOM 14125 C CG . ASN H 1 102 ? 69.052 2.826 45.678 1.00 105.95 ? 102 ASN H CG 1 +ATOM 14126 O OD1 . ASN H 1 102 ? 68.487 3.919 45.847 1.00 62.64 ? 102 ASN H OD1 1 +ATOM 14127 N ND2 . ASN H 1 102 ? 68.412 1.658 45.748 1.00 116.95 ? 102 ASN H ND2 1 +ATOM 14128 N N . GLY H 1 103 ? 72.919 2.651 42.797 1.00 122.87 ? 103 GLY H N 1 +ATOM 14129 C CA . GLY H 1 103 ? 74.353 2.845 42.576 1.00 129.74 ? 103 GLY H CA 1 +ATOM 14130 C C . GLY H 1 103 ? 75.231 2.688 43.819 1.00 133.92 ? 103 GLY H C 1 +ATOM 14131 O O . GLY H 1 103 ? 76.237 3.373 43.986 1.00 104.16 ? 103 GLY H O 1 +ATOM 14132 N N . THR H 1 104 ? 74.847 1.771 44.695 1.00 155.25 ? 104 THR H N 1 +ATOM 14133 C CA . THR H 1 104 ? 75.717 1.361 45.773 1.00 150.30 ? 104 THR H CA 1 +ATOM 14134 C C . THR H 1 104 ? 76.387 0.041 45.427 1.00 102.43 ? 104 THR H C 1 +ATOM 14135 O O . THR H 1 104 ? 77.480 -0.215 45.881 1.00 103.94 ? 104 THR H O 1 +ATOM 14136 C CB . THR H 1 104 ? 74.957 1.248 47.121 1.00 191.08 ? 104 THR H CB 1 +ATOM 14137 O OG1 . THR H 1 104 ? 73.972 0.209 47.067 1.00 184.35 ? 104 THR H OG1 1 +ATOM 14138 C CG2 . THR H 1 104 ? 74.273 2.577 47.474 1.00 190.31 ? 104 THR H CG2 1 +ATOM 14139 N N . VAL H 1 105 ? 75.733 -0.783 44.623 1.00 84.15 ? 105 VAL H N 1 +ATOM 14140 C CA . VAL H 1 105 ? 76.223 -2.127 44.391 1.00 112.28 ? 105 VAL H CA 1 +ATOM 14141 C C . VAL H 1 105 ? 77.650 -2.091 43.819 1.00 132.10 ? 105 VAL H C 1 +ATOM 14142 O O . VAL H 1 105 ? 77.983 -1.276 42.941 1.00 82.46 ? 105 VAL H O 1 +ATOM 14143 C CB . VAL H 1 105 ? 75.258 -2.999 43.513 1.00 142.21 ? 105 VAL H CB 1 +ATOM 14144 C CG1 . VAL H 1 105 ? 76.017 -4.004 42.629 1.00 159.47 ? 105 VAL H CG1 1 +ATOM 14145 C CG2 . VAL H 1 105 ? 74.257 -3.752 44.385 1.00 107.29 ? 105 VAL H CG2 1 +ATOM 14146 N N . ALA H 1 106 ? 78.458 -3.044 44.298 1.00 157.43 ? 106 ALA H N 1 +ATOM 14147 C CA . ALA H 1 106 ? 79.884 -3.128 43.996 1.00 135.15 ? 106 ALA H CA 1 +ATOM 14148 C C . ALA H 1 106 ? 80.126 -3.346 42.505 1.00 154.76 ? 106 ALA H C 1 +ATOM 14149 O O . ALA H 1 106 ? 79.494 -4.202 41.881 1.00 222.89 ? 106 ALA H O 1 +ATOM 14150 C CB . ALA H 1 106 ? 80.524 -4.249 44.808 1.00 105.35 ? 106 ALA H CB 1 +ATOM 14151 N N . ILE H 1 107 ? 81.048 -2.570 41.946 1.00 147.63 ? 107 ILE H N 1 +ATOM 14152 C CA . ILE H 1 107 ? 81.300 -2.564 40.506 1.00 137.26 ? 107 ILE H CA 1 +ATOM 14153 C C . ILE H 1 107 ? 81.695 -3.955 39.951 1.00 133.85 ? 107 ILE H C 1 +ATOM 14154 O O . ILE H 1 107 ? 81.399 -4.290 38.802 1.00 122.07 ? 107 ILE H O 1 +ATOM 14155 C CB . ILE H 1 107 ? 82.384 -1.516 40.161 1.00 143.63 ? 107 ILE H CB 1 +ATOM 14156 C CG1 . ILE H 1 107 ? 82.447 -1.268 38.653 1.00 150.95 ? 107 ILE H CG1 1 +ATOM 14157 C CG2 . ILE H 1 107 ? 83.752 -1.946 40.693 1.00 143.98 ? 107 ILE H CG2 1 +ATOM 14158 C CD1 . ILE H 1 107 ? 81.137 -0.816 38.036 1.00 146.77 ? 107 ILE H CD1 1 +ATOM 14159 N N . ASN H 1 108 ? 82.346 -4.766 40.781 1.00 132.87 ? 108 ASN H N 1 +ATOM 14160 C CA . ASN H 1 108 ? 82.687 -6.151 40.429 1.00 124.78 ? 108 ASN H CA 1 +ATOM 14161 C C . ASN H 1 108 ? 81.443 -7.028 40.378 1.00 135.35 ? 108 ASN H C 1 +ATOM 14162 O O . ASN H 1 108 ? 81.347 -7.953 39.573 1.00 176.38 ? 108 ASN H O 1 +ATOM 14163 C CB . ASN H 1 108 ? 83.662 -6.749 41.455 1.00 130.36 ? 108 ASN H CB 1 +ATOM 14164 C CG . ASN H 1 108 ? 84.577 -5.706 42.074 1.00 162.88 ? 108 ASN H CG 1 +ATOM 14165 O OD1 . ASN H 1 108 ? 85.631 -5.386 41.524 1.00 197.41 ? 108 ASN H OD1 1 +ATOM 14166 N ND2 . ASN H 1 108 ? 84.167 -5.156 43.213 1.00 164.62 ? 108 ASN H ND2 1 +ATOM 14167 N N . ASN H 1 109 ? 80.503 -6.740 41.269 1.00 151.18 ? 109 ASN H N 1 +ATOM 14168 C CA . ASN H 1 109 ? 79.306 -7.557 41.442 1.00 146.69 ? 109 ASN H CA 1 +ATOM 14169 C C . ASN H 1 109 ? 78.182 -7.178 40.481 1.00 133.54 ? 109 ASN H C 1 +ATOM 14170 O O . ASN H 1 109 ? 77.230 -7.940 40.284 1.00 137.31 ? 109 ASN H O 1 +ATOM 14171 C CB . ASN H 1 109 ? 78.824 -7.444 42.890 1.00 156.58 ? 109 ASN H CB 1 +ATOM 14172 C CG . ASN H 1 109 ? 78.886 -8.764 43.619 1.00 183.70 ? 109 ASN H CG 1 +ATOM 14173 O OD1 . ASN H 1 109 ? 77.855 -9.326 43.985 1.00 247.59 ? 109 ASN H OD1 1 +ATOM 14174 N ND2 . ASN H 1 109 ? 80.094 -9.297 43.792 1.00 170.90 ? 109 ASN H ND2 1 +ATOM 14175 N N . ARG H 1 110 ? 78.301 -5.988 39.892 1.00 127.91 ? 110 ARG H N 1 +ATOM 14176 C CA . ARG H 1 110 ? 77.238 -5.379 39.073 1.00 109.42 ? 110 ARG H CA 1 +ATOM 14177 C C . ARG H 1 110 ? 76.836 -6.303 37.919 1.00 93.37 ? 110 ARG H C 1 +ATOM 14178 O O . ARG H 1 110 ? 77.709 -6.835 37.229 1.00 73.03 ? 110 ARG H O 1 +ATOM 14179 C CB . ARG H 1 110 ? 77.740 -4.025 38.516 1.00 99.02 ? 110 ARG H CB 1 +ATOM 14180 C CG . ARG H 1 110 ? 76.649 -3.043 38.125 1.00 102.74 ? 110 ARG H CG 1 +ATOM 14181 C CD . ARG H 1 110 ? 77.064 -1.604 38.380 1.00 112.06 ? 110 ARG H CD 1 +ATOM 14182 N NE . ARG H 1 110 ? 77.768 -1.010 37.235 1.00 108.49 ? 110 ARG H NE 1 +ATOM 14183 C CZ . ARG H 1 110 ? 77.364 0.078 36.568 1.00 127.40 ? 110 ARG H CZ 1 +ATOM 14184 N NH1 . ARG H 1 110 ? 76.236 0.721 36.904 1.00 140.34 ? 110 ARG H NH1 1 +ATOM 14185 N NH2 . ARG H 1 110 ? 78.096 0.543 35.559 1.00 103.02 ? 110 ARG H NH2 1 +ATOM 14186 N N . ILE H 1 111 ? 75.532 -6.464 37.691 1.00 80.77 ? 111 ILE H N 1 +ATOM 14187 C CA . ILE H 1 111 ? 75.061 -7.179 36.502 1.00 88.30 ? 111 ILE H CA 1 +ATOM 14188 C C . ILE H 1 111 ? 74.437 -6.235 35.492 1.00 92.82 ? 111 ILE H C 1 +ATOM 14189 O O . ILE H 1 111 ? 73.433 -5.615 35.786 1.00 96.95 ? 111 ILE H O 1 +ATOM 14190 C CB . ILE H 1 111 ? 74.016 -8.237 36.856 1.00 94.88 ? 111 ILE H CB 1 +ATOM 14191 C CG1 . ILE H 1 111 ? 74.655 -9.302 37.770 1.00 110.88 ? 111 ILE H CG1 1 +ATOM 14192 C CG2 . ILE H 1 111 ? 73.464 -8.880 35.584 1.00 89.00 ? 111 ILE H CG2 1 +ATOM 14193 C CD1 . ILE H 1 111 ? 73.680 -10.268 38.431 1.00 80.01 ? 111 ILE H CD1 1 +ATOM 14194 N N . PRO H 1 112 ? 75.045 -6.111 34.300 1.00 91.39 ? 112 PRO H N 1 +ATOM 14195 C CA . PRO H 1 112 ? 74.528 -5.189 33.299 1.00 87.95 ? 112 PRO H CA 1 +ATOM 14196 C C . PRO H 1 112 ? 73.331 -5.774 32.559 1.00 99.99 ? 112 PRO H C 1 +ATOM 14197 O O . PRO H 1 112 ? 73.386 -6.925 32.096 1.00 117.91 ? 112 PRO H O 1 +ATOM 14198 C CB . PRO H 1 112 ? 75.709 -5.018 32.357 1.00 98.73 ? 112 PRO H CB 1 +ATOM 14199 C CG . PRO H 1 112 ? 76.419 -6.336 32.412 1.00 111.51 ? 112 PRO H CG 1 +ATOM 14200 C CD . PRO H 1 112 ? 76.156 -6.926 33.773 1.00 101.33 ? 112 PRO H CD 1 +ATOM 14201 N N . LEU H 1 113 ? 72.246 -5.002 32.497 1.00 125.65 ? 113 LEU H N 1 +ATOM 14202 C CA . LEU H 1 113 ? 70.967 -5.483 31.979 1.00 116.95 ? 113 LEU H CA 1 +ATOM 14203 C C . LEU H 1 113 ? 70.582 -4.844 30.666 1.00 82.93 ? 113 LEU H C 1 +ATOM 14204 O O . LEU H 1 113 ? 70.742 -3.637 30.425 1.00 61.08 ? 113 LEU H O 1 +ATOM 14205 C CB . LEU H 1 113 ? 69.831 -5.230 32.965 1.00 131.16 ? 113 LEU H CB 1 +ATOM 14206 C CG . LEU H 1 113 ? 69.623 -6.296 34.038 1.00 119.45 ? 113 LEU H CG 1 +ATOM 14207 C CD1 . LEU H 1 113 ? 68.397 -5.894 34.823 1.00 123.16 ? 113 LEU H CD1 1 +ATOM 14208 C CD2 . LEU H 1 113 ? 69.453 -7.690 33.466 1.00 104.97 ? 113 LEU H CD2 1 +ATOM 14209 N N . GLN H 1 114 ? 70.047 -5.696 29.826 1.00 75.89 ? 114 GLN H N 1 +ATOM 14210 C CA . GLN H 1 114 ? 69.843 -5.366 28.451 1.00 103.62 ? 114 GLN H CA 1 +ATOM 14211 C C . GLN H 1 114 ? 68.525 -6.012 28.111 1.00 92.53 ? 114 GLN H C 1 +ATOM 14212 O O . GLN H 1 114 ? 68.185 -7.052 28.679 1.00 91.16 ? 114 GLN H O 1 +ATOM 14213 C CB . GLN H 1 114 ? 70.975 -5.944 27.584 1.00 127.77 ? 114 GLN H CB 1 +ATOM 14214 C CG . GLN H 1 114 ? 71.311 -5.111 26.347 1.00 101.72 ? 114 GLN H CG 1 +ATOM 14215 C CD . GLN H 1 114 ? 71.936 -5.954 25.263 1.00 119.69 ? 114 GLN H CD 1 +ATOM 14216 O OE1 . GLN H 1 114 ? 72.570 -6.987 25.554 1.00 153.41 ? 114 GLN H OE1 1 +ATOM 14217 N NE2 . GLN H 1 114 ? 71.662 -5.605 24.008 1.00 103.71 ? 114 GLN H NE2 1 +ATOM 14218 N N . SER H 1 115 ? 67.792 -5.381 27.201 1.00 74.38 ? 115 SER H N 1 +ATOM 14219 C CA . SER H 1 115 ? 66.476 -5.817 26.851 1.00 74.42 ? 115 SER H CA 1 +ATOM 14220 C C . SER H 1 115 ? 66.539 -7.274 26.422 1.00 71.47 ? 115 SER H C 1 +ATOM 14221 O O . SER H 1 115 ? 67.572 -7.754 25.926 1.00 46.29 ? 115 SER H O 1 +ATOM 14222 C CB . SER H 1 115 ? 65.877 -4.927 25.754 1.00 88.42 ? 115 SER H CB 1 +ATOM 14223 O OG . SER H 1 115 ? 66.759 -4.807 24.637 1.00 157.74 ? 115 SER H OG 1 +ATOM 14224 N N . LEU H 1 116 ? 65.408 -7.968 26.552 1.00 94.80 ? 116 LEU H N 1 +ATOM 14225 C CA . LEU H 1 116 ? 65.420 -9.398 26.345 1.00 99.39 ? 116 LEU H CA 1 +ATOM 14226 C C . LEU H 1 116 ? 65.567 -9.642 24.860 1.00 123.42 ? 116 LEU H C 1 +ATOM 14227 O O . LEU H 1 116 ? 64.814 -9.078 24.067 1.00 103.01 ? 116 LEU H O 1 +ATOM 14228 C CB . LEU H 1 116 ? 64.149 -10.063 26.856 1.00 82.13 ? 116 LEU H CB 1 +ATOM 14229 C CG . LEU H 1 116 ? 63.944 -10.000 28.360 1.00 77.67 ? 116 LEU H CG 1 +ATOM 14230 C CD1 . LEU H 1 116 ? 63.070 -8.787 28.743 1.00 72.73 ? 116 LEU H CD1 1 +ATOM 14231 C CD2 . LEU H 1 116 ? 63.302 -11.311 28.800 1.00 72.05 ? 116 LEU H CD2 1 +ATOM 14232 N N . THR H 1 117 ? 66.586 -10.418 24.493 1.00 143.51 ? 117 THR H N 1 +ATOM 14233 C CA . THR H 1 117 ? 66.848 -10.759 23.098 1.00 140.50 ? 117 THR H CA 1 +ATOM 14234 C C . THR H 1 117 ? 65.606 -11.387 22.503 1.00 104.44 ? 117 THR H C 1 +ATOM 14235 O O . THR H 1 117 ? 64.974 -12.230 23.149 1.00 80.13 ? 117 THR H O 1 +ATOM 14236 C CB . THR H 1 117 ? 67.991 -11.780 22.962 1.00 153.08 ? 117 THR H CB 1 +ATOM 14237 O OG1 . THR H 1 117 ? 69.164 -11.292 23.627 1.00 163.60 ? 117 THR H OG1 1 +ATOM 14238 C CG2 . THR H 1 117 ? 68.312 -12.005 21.501 1.00 161.41 ? 117 THR H CG2 1 +ATOM 14239 N N . ALA H 1 118 ? 65.226 -10.919 21.317 1.00 99.19 ? 118 ALA H N 1 +ATOM 14240 C CA . ALA H 1 118 ? 63.911 -11.222 20.758 1.00 102.06 ? 118 ALA H CA 1 +ATOM 14241 C C . ALA H 1 118 ? 64.053 -12.061 19.506 1.00 105.36 ? 118 ALA H C 1 +ATOM 14242 O O . ALA H 1 118 ? 64.881 -11.769 18.651 1.00 72.34 ? 118 ALA H O 1 +ATOM 14243 C CB . ALA H 1 118 ? 63.114 -9.947 20.455 1.00 66.92 ? 118 ALA H CB 1 +ATOM 14244 N N . ALA H 1 119 ? 63.133 -13.020 19.372 1.00 108.32 ? 119 ALA H N 1 +ATOM 14245 C CA . ALA H 1 119 ? 63.151 -14.005 18.297 1.00 86.85 ? 119 ALA H CA 1 +ATOM 14246 C C . ALA H 1 119 ? 62.441 -13.519 17.045 1.00 71.85 ? 119 ALA H C 1 +ATOM 14247 O O . ALA H 1 119 ? 61.538 -12.671 17.135 1.00 64.66 ? 119 ALA H O 1 +ATOM 14248 C CB . ALA H 1 119 ? 62.506 -15.287 18.779 1.00 81.20 ? 119 ALA H CB 1 +ATOM 14249 N N . ASN H 1 120 ? 62.824 -14.058 15.892 1.00 72.69 ? 120 ASN H N 1 +ATOM 14250 C CA . ASN H 1 120 ? 62.117 -13.722 14.669 1.00 108.96 ? 120 ASN H CA 1 +ATOM 14251 C C . ASN H 1 120 ? 61.117 -14.794 14.277 1.00 114.06 ? 120 ASN H C 1 +ATOM 14252 O O . ASN H 1 120 ? 59.991 -14.497 13.848 1.00 147.74 ? 120 ASN H O 1 +ATOM 14253 C CB . ASN H 1 120 ? 63.060 -13.473 13.494 1.00 131.90 ? 120 ASN H CB 1 +ATOM 14254 C CG . ASN H 1 120 ? 62.303 -13.023 12.225 1.00 131.21 ? 120 ASN H CG 1 +ATOM 14255 O OD1 . ASN H 1 120 ? 62.631 -13.498 11.134 1.00 189.63 ? 120 ASN H OD1 1 +ATOM 14256 N ND2 . ASN H 1 120 ? 61.246 -12.175 12.368 1.00 66.01 ? 120 ASN H ND2 1 +ATOM 14257 N N . ILE H 1 121 ? 61.549 -16.041 14.333 1.00 92.19 ? 121 ILE H N 1 +ATOM 14258 C CA . ILE H 1 121 ? 60.626 -17.126 14.069 1.00 97.19 ? 121 ILE H CA 1 +ATOM 14259 C C . ILE H 1 121 ? 60.451 -17.834 15.385 1.00 97.02 ? 121 ILE H C 1 +ATOM 14260 O O . ILE H 1 121 ? 61.386 -17.955 16.174 1.00 100.71 ? 121 ILE H O 1 +ATOM 14261 C CB . ILE H 1 121 ? 61.116 -18.099 12.966 1.00 107.98 ? 121 ILE H CB 1 +ATOM 14262 C CG1 . ILE H 1 121 ? 62.299 -18.969 13.447 1.00 127.17 ? 121 ILE H CG1 1 +ATOM 14263 C CG2 . ILE H 1 121 ? 61.488 -17.337 11.700 1.00 108.45 ? 121 ILE H CG2 1 +ATOM 14264 C CD1 . ILE H 1 121 ? 61.949 -20.429 13.627 1.00 112.28 ? 121 ILE H CD1 1 +ATOM 14265 N N . MET H 1 122 ? 59.240 -18.279 15.646 1.00 78.37 ? 122 MET H N 1 +ATOM 14266 C CA . MET H 1 122 ? 59.056 -19.172 16.757 1.00 60.05 ? 122 MET H CA 1 +ATOM 14267 C C . MET H 1 122 ? 58.422 -20.443 16.262 1.00 59.04 ? 122 MET H C 1 +ATOM 14268 O O . MET H 1 122 ? 57.667 -20.450 15.271 1.00 77.48 ? 122 MET H O 1 +ATOM 14269 C CB . MET H 1 122 ? 58.214 -18.500 17.828 1.00 71.00 ? 122 MET H CB 1 +ATOM 14270 C CG . MET H 1 122 ? 56.843 -17.988 17.385 1.00 66.51 ? 122 MET H CG 1 +ATOM 14271 S SD . MET H 1 122 ? 55.717 -18.102 18.788 1.00 82.83 ? 122 MET H SD 1 +ATOM 14272 C CE . MET H 1 122 ? 54.211 -18.645 18.039 1.00 73.89 ? 122 MET H CE 1 +ATOM 14273 N N . VAL H 1 123 ? 58.809 -21.549 16.864 1.00 69.05 ? 123 VAL H N 1 +ATOM 14274 C CA . VAL H 1 123 ? 58.353 -22.855 16.393 1.00 98.00 ? 123 VAL H CA 1 +ATOM 14275 C C . VAL H 1 123 ? 57.606 -23.516 17.515 1.00 102.89 ? 123 VAL H C 1 +ATOM 14276 O O . VAL H 1 123 ? 58.132 -23.693 18.596 1.00 109.13 ? 123 VAL H O 1 +ATOM 14277 C CB . VAL H 1 123 ? 59.507 -23.792 15.924 1.00 122.74 ? 123 VAL H CB 1 +ATOM 14278 C CG1 . VAL H 1 123 ? 60.725 -23.671 16.830 1.00 127.78 ? 123 VAL H CG1 1 +ATOM 14279 C CG2 . VAL H 1 123 ? 59.036 -25.246 15.834 1.00 129.93 ? 123 VAL H CG2 1 +ATOM 14280 N N . GLU H 1 124 ? 56.383 -23.934 17.228 1.00 126.91 ? 124 GLU H N 1 +ATOM 14281 C CA . GLU H 1 124 ? 55.618 -24.741 18.179 1.00 108.39 ? 124 GLU H CA 1 +ATOM 14282 C C . GLU H 1 124 ? 55.100 -25.985 17.512 1.00 91.44 ? 124 GLU H C 1 +ATOM 14283 O O . GLU H 1 124 ? 55.165 -26.142 16.286 1.00 102.17 ? 124 GLU H O 1 +ATOM 14284 C CB . GLU H 1 124 ? 54.461 -23.943 18.765 1.00 126.61 ? 124 GLU H CB 1 +ATOM 14285 C CG . GLU H 1 124 ? 53.883 -22.866 17.851 1.00 146.16 ? 124 GLU H CG 1 +ATOM 14286 C CD . GLU H 1 124 ? 53.074 -21.849 18.627 1.00 152.54 ? 124 GLU H CD 1 +ATOM 14287 O OE1 . GLU H 1 124 ? 53.460 -21.527 19.777 1.00 143.59 ? 124 GLU H OE1 1 +ATOM 14288 O OE2 . GLU H 1 124 ? 52.036 -21.411 18.094 1.00 160.61 ? 124 GLU H OE2 1 +ATOM 14289 N N . GLY H 1 125 ? 54.557 -26.866 18.323 1.00 78.80 ? 125 GLY H N 1 +ATOM 14290 C CA . GLY H 1 125 ? 54.094 -28.144 17.816 1.00 77.68 ? 125 GLY H CA 1 +ATOM 14291 C C . GLY H 1 125 ? 53.353 -28.929 18.874 1.00 70.34 ? 125 GLY H C 1 +ATOM 14292 O O . GLY H 1 125 ? 52.911 -28.376 19.888 1.00 70.13 ? 125 GLY H O 1 +ATOM 14293 N N . SER H 1 126 ? 53.236 -30.230 18.658 1.00 64.76 ? 126 SER H N 1 +ATOM 14294 C CA . SER H 1 126 ? 52.459 -31.058 19.552 1.00 78.48 ? 126 SER H CA 1 +ATOM 14295 C C . SER H 1 126 ? 52.894 -32.502 19.391 1.00 57.60 ? 126 SER H C 1 +ATOM 14296 O O . SER H 1 126 ? 53.185 -32.906 18.284 1.00 39.17 ? 126 SER H O 1 +ATOM 14297 C CB . SER H 1 126 ? 50.954 -30.903 19.236 1.00 108.03 ? 126 SER H CB 1 +ATOM 14298 O OG . SER H 1 126 ? 50.606 -29.607 18.733 1.00 141.50 ? 126 SER H OG 1 +ATOM 14299 N N . ILE H 1 127 ? 52.795 -33.273 20.470 1.00 44.00 ? 127 ILE H N 1 +ATOM 14300 C CA . ILE H 1 127 ? 52.752 -34.677 20.323 1.00 57.88 ? 127 ILE H CA 1 +ATOM 14301 C C . ILE H 1 127 ? 51.376 -35.104 19.851 1.00 73.97 ? 127 ILE H C 1 +ATOM 14302 O O . ILE H 1 127 ? 50.432 -35.191 20.608 1.00 81.14 ? 127 ILE H O 1 +ATOM 14303 C CB . ILE H 1 127 ? 53.110 -35.413 21.603 1.00 75.24 ? 127 ILE H CB 1 +ATOM 14304 C CG1 . ILE H 1 127 ? 54.572 -35.096 21.985 1.00 94.00 ? 127 ILE H CG1 1 +ATOM 14305 C CG2 . ILE H 1 127 ? 52.940 -36.933 21.425 1.00 83.79 ? 127 ILE H CG2 1 +ATOM 14306 C CD1 . ILE H 1 127 ? 54.845 -35.127 23.483 1.00 85.96 ? 127 ILE H CD1 1 +ATOM 14307 N N . ILE H 1 128 ? 51.275 -35.376 18.550 1.00 104.39 ? 128 ILE H N 1 +ATOM 14308 C CA . ILE H 1 128 ? 50.028 -35.832 17.895 1.00 80.94 ? 128 ILE H CA 1 +ATOM 14309 C C . ILE H 1 128 ? 50.061 -37.361 17.920 1.00 86.26 ? 128 ILE H C 1 +ATOM 14310 O O . ILE H 1 128 ? 50.807 -38.011 17.188 1.00 118.57 ? 128 ILE H O 1 +ATOM 14311 C CB . ILE H 1 128 ? 49.917 -35.259 16.460 1.00 63.64 ? 128 ILE H CB 1 +ATOM 14312 C CG1 . ILE H 1 128 ? 51.169 -35.581 15.626 1.00 86.23 ? 128 ILE H CG1 1 +ATOM 14313 C CG2 . ILE H 1 128 ? 49.891 -33.741 16.514 1.00 65.89 ? 128 ILE H CG2 1 +ATOM 14314 C CD1 . ILE H 1 128 ? 50.927 -35.576 14.127 1.00 74.79 ? 128 ILE H CD1 1 +ATOM 14315 N N . GLY H 1 129 ? 49.404 -37.918 18.912 1.00 78.28 ? 129 GLY H N 1 +ATOM 14316 C CA . GLY H 1 129 ? 49.093 -39.318 18.878 1.00 76.68 ? 129 GLY H CA 1 +ATOM 14317 C C . GLY H 1 129 ? 50.124 -40.233 19.483 1.00 81.21 ? 129 GLY H C 1 +ATOM 14318 O O . GLY H 1 129 ? 51.358 -40.138 19.229 1.00 70.25 ? 129 GLY H O 1 +ATOM 14319 N N . TYR H 1 130 ? 49.591 -41.207 20.219 1.00 78.32 ? 130 TYR H N 1 +ATOM 14320 C CA . TYR H 1 130 ? 50.342 -42.394 20.579 1.00 99.30 ? 130 TYR H CA 1 +ATOM 14321 C C . TYR H 1 130 ? 49.329 -43.489 20.495 1.00 95.14 ? 130 TYR H C 1 +ATOM 14322 O O . TYR H 1 130 ? 48.452 -43.589 21.333 1.00 104.93 ? 130 TYR H O 1 +ATOM 14323 C CB . TYR H 1 130 ? 50.948 -42.274 22.002 1.00 110.50 ? 130 TYR H CB 1 +ATOM 14324 C CG . TYR H 1 130 ? 51.643 -43.508 22.566 1.00 92.65 ? 130 TYR H CG 1 +ATOM 14325 C CD1 . TYR H 1 130 ? 50.909 -44.647 22.912 1.00 76.22 ? 130 TYR H CD1 1 +ATOM 14326 C CD2 . TYR H 1 130 ? 53.018 -43.503 22.809 1.00 100.22 ? 130 TYR H CD2 1 +ATOM 14327 C CE1 . TYR H 1 130 ? 51.529 -45.756 23.438 1.00 74.98 ? 130 TYR H CE1 1 +ATOM 14328 C CE2 . TYR H 1 130 ? 53.656 -44.630 23.286 1.00 102.67 ? 130 TYR H CE2 1 +ATOM 14329 C CZ . TYR H 1 130 ? 52.910 -45.748 23.608 1.00 81.35 ? 130 TYR H CZ 1 +ATOM 14330 O OH . TYR H 1 130 ? 53.566 -46.848 24.118 1.00 81.72 ? 130 TYR H OH 1 +ATOM 14331 N N . GLU H 1 131 ? 49.466 -44.333 19.481 1.00 119.88 ? 131 GLU H N 1 +ATOM 14332 C CA . GLU H 1 131 ? 48.684 -45.564 19.412 1.00 138.04 ? 131 GLU H CA 1 +ATOM 14333 C C . GLU H 1 131 ? 49.513 -46.744 19.902 1.00 95.08 ? 131 GLU H C 1 +ATOM 14334 O O . GLU H 1 131 ? 50.734 -46.726 19.796 1.00 72.97 ? 131 GLU H O 1 +ATOM 14335 C CB . GLU H 1 131 ? 48.229 -45.788 17.981 1.00 159.13 ? 131 GLU H CB 1 +ATOM 14336 C CG . GLU H 1 131 ? 47.191 -46.878 17.801 1.00 148.00 ? 131 GLU H CG 1 +ATOM 14337 C CD . GLU H 1 131 ? 45.760 -46.387 17.982 1.00 125.74 ? 131 GLU H CD 1 +ATOM 14338 O OE1 . GLU H 1 131 ? 45.485 -45.183 17.704 1.00 76.63 ? 131 GLU H OE1 1 +ATOM 14339 O OE2 . GLU H 1 131 ? 44.903 -47.231 18.349 1.00 154.43 ? 131 GLU H OE2 1 +ATOM 14340 N N . SER H 1 132 ? 48.857 -47.708 20.539 1.00 84.30 ? 132 SER H N 1 +ATOM 14341 C CA . SER H 1 132 ? 49.575 -48.751 21.265 1.00 96.30 ? 132 SER H CA 1 +ATOM 14342 C C . SER H 1 132 ? 49.258 -50.134 20.718 1.00 102.18 ? 132 SER H C 1 +ATOM 14343 O O . SER H 1 132 ? 48.105 -50.427 20.388 1.00 132.60 ? 132 SER H O 1 +ATOM 14344 C CB . SER H 1 132 ? 49.262 -48.694 22.772 1.00 102.73 ? 132 SER H CB 1 +ATOM 14345 O OG . SER H 1 132 ? 48.538 -49.849 23.192 1.00 96.74 ? 132 SER H OG 1 +ATOM 14346 N N . ASN H 1 133 ? 50.272 -50.997 20.675 1.00 101.74 ? 133 ASN H N 1 +ATOM 14347 C CA . ASN H 1 133 ? 50.177 -52.283 19.962 1.00 108.59 ? 133 ASN H CA 1 +ATOM 14348 C C . ASN H 1 133 ? 49.569 -52.122 18.574 1.00 92.14 ? 133 ASN H C 1 +ATOM 14349 O O . ASN H 1 133 ? 48.552 -52.736 18.247 1.00 77.20 ? 133 ASN H O 1 +ATOM 14350 C CB . ASN H 1 133 ? 49.365 -53.307 20.754 1.00 109.13 ? 133 ASN H CB 1 +ATOM 14351 C CG . ASN H 1 133 ? 49.968 -53.599 22.101 1.00 126.44 ? 133 ASN H CG 1 +ATOM 14352 O OD1 . ASN H 1 133 ? 51.194 -53.499 22.303 1.00 159.76 ? 133 ASN H OD1 1 +ATOM 14353 N ND2 . ASN H 1 133 ? 49.112 -53.935 23.050 1.00 118.16 ? 133 ASN H ND2 1 +ATOM 14354 N N . VAL H 1 134 ? 50.184 -51.251 17.790 1.00 81.08 ? 134 VAL H N 1 +ATOM 14355 C CA . VAL H 1 134 ? 49.742 -50.989 16.442 1.00 95.64 ? 134 VAL H CA 1 +ATOM 14356 C C . VAL H 1 134 ? 49.980 -52.265 15.636 1.00 123.95 ? 134 VAL H C 1 +ATOM 14357 O O . VAL H 1 134 ? 49.195 -52.618 14.750 1.00 202.12 ? 134 VAL H O 1 +ATOM 14358 C CB . VAL H 1 134 ? 50.513 -49.793 15.833 1.00 106.46 ? 134 VAL H CB 1 +ATOM 14359 C CG1 . VAL H 1 134 ? 50.010 -49.465 14.437 1.00 108.55 ? 134 VAL H CG1 1 +ATOM 14360 C CG2 . VAL H 1 134 ? 50.382 -48.566 16.733 1.00 116.35 ? 134 VAL H CG2 1 +ATOM 14361 N N . LYS H 1 135 ? 51.055 -52.977 15.971 1.00 133.24 ? 135 LYS H N 1 +ATOM 14362 C CA . LYS H 1 135 ? 51.219 -54.370 15.532 1.00 99.26 ? 135 LYS H CA 1 +ATOM 14363 C C . LYS H 1 135 ? 51.698 -55.242 16.686 1.00 91.85 ? 135 LYS H C 1 +ATOM 14364 O O . LYS H 1 135 ? 52.335 -54.754 17.642 1.00 90.19 ? 135 LYS H O 1 +ATOM 14365 C CB . LYS H 1 135 ? 52.206 -54.449 14.359 1.00 83.01 ? 135 LYS H CB 1 +ATOM 14366 C CG . LYS H 1 135 ? 51.738 -53.698 13.132 1.00 69.68 ? 135 LYS H CG 1 +ATOM 14367 C CD . LYS H 1 135 ? 52.807 -53.713 12.070 1.00 79.91 ? 135 LYS H CD 1 +ATOM 14368 C CE . LYS H 1 135 ? 52.358 -52.967 10.828 1.00 93.57 ? 135 LYS H CE 1 +ATOM 14369 N NZ . LYS H 1 135 ? 53.143 -53.408 9.640 1.00 96.33 ? 135 LYS H NZ 1 +ATOM 14370 N N . SER H 1 136 ? 51.500 -56.542 16.527 1.00 84.88 ? 136 SER H N 1 +ATOM 14371 C CA . SER H 1 136 ? 51.977 -57.504 17.504 1.00 101.71 ? 136 SER H CA 1 +ATOM 14372 C C . SER H 1 136 ? 52.024 -58.926 16.937 1.00 119.30 ? 136 SER H C 1 +ATOM 14373 O O . SER H 1 136 ? 51.321 -59.236 15.988 1.00 152.42 ? 136 SER H O 1 +ATOM 14374 C CB . SER H 1 136 ? 51.099 -57.445 18.755 1.00 95.38 ? 136 SER H CB 1 +ATOM 14375 O OG . SER H 1 136 ? 50.564 -58.721 19.080 1.00 89.17 ? 136 SER H OG 1 +ATOM 14376 N N . GLY H 1 137 ? 52.844 -59.783 17.544 1.00 131.75 ? 137 GLY H N 1 +ATOM 14377 C CA . GLY H 1 137 ? 52.915 -61.186 17.147 1.00 149.38 ? 137 GLY H CA 1 +ATOM 14378 C C . GLY H 1 137 ? 53.650 -62.075 18.137 1.00 175.03 ? 137 GLY H C 1 +ATOM 14379 O O . GLY H 1 137 ? 54.187 -61.604 19.141 1.00 203.30 ? 137 GLY H O 1 +ATOM 14380 N N . GLY H 1 138 ? 53.662 -63.375 17.861 1.00 186.26 ? 138 GLY H N 1 +ATOM 14381 C CA . GLY H 1 138 ? 54.375 -64.331 18.705 1.00 185.36 ? 138 GLY H CA 1 +ATOM 14382 C C . GLY H 1 138 ? 54.589 -65.673 18.037 1.00 186.85 ? 138 GLY H C 1 +ATOM 14383 O O . GLY H 1 138 ? 53.757 -66.120 17.248 1.00 216.84 ? 138 GLY H O 1 +ATOM 14384 N N . VAL H 1 139 ? 55.730 -66.295 18.323 1.00 174.02 ? 139 VAL H N 1 +ATOM 14385 C CA . VAL H 1 139 ? 56.049 -67.618 17.794 1.00 151.63 ? 139 VAL H CA 1 +ATOM 14386 C C . VAL H 1 139 ? 56.701 -68.468 18.875 1.00 148.30 ? 139 VAL H C 1 +ATOM 14387 O O . VAL H 1 139 ? 57.702 -68.062 19.478 1.00 151.27 ? 139 VAL H O 1 +ATOM 14388 C CB . VAL H 1 139 ? 57.010 -67.542 16.590 1.00 151.69 ? 139 VAL H CB 1 +ATOM 14389 C CG1 . VAL H 1 139 ? 57.413 -68.943 16.160 1.00 158.13 ? 139 VAL H CG1 1 +ATOM 14390 C CG2 . VAL H 1 139 ? 56.375 -66.789 15.429 1.00 147.19 ? 139 VAL H CG2 1 +ATOM 14391 N N . GLY H 1 140 ? 56.142 -69.653 19.110 1.00 147.45 ? 140 GLY H N 1 +ATOM 14392 C CA . GLY H 1 140 ? 56.658 -70.557 20.135 1.00 163.01 ? 140 GLY H CA 1 +ATOM 14393 C C . GLY H 1 140 ? 56.474 -72.027 19.819 1.00 172.12 ? 140 GLY H C 1 +ATOM 14394 O O . GLY H 1 140 ? 55.487 -72.422 19.205 1.00 181.14 ? 140 GLY H O 1 +ATOM 14395 N N . ALA H 1 141 ? 57.438 -72.841 20.241 1.00 190.24 ? 141 ALA H N 1 +ATOM 14396 C CA . ALA H 1 141 ? 57.355 -74.284 20.048 1.00 179.27 ? 141 ALA H CA 1 +ATOM 14397 C C . ALA H 1 141 ? 57.925 -75.054 21.241 1.00 182.08 ? 141 ALA H C 1 +ATOM 14398 O O . ALA H 1 141 ? 58.923 -74.654 21.845 1.00 171.64 ? 141 ALA H O 1 +ATOM 14399 C CB . ALA H 1 141 ? 58.057 -74.684 18.761 1.00 143.96 ? 141 ALA H CB 1 +ATOM 14400 N N . ARG H 1 142 ? 57.238 -76.122 21.616 1.00 175.81 ? 142 ARG H N 1 +ATOM 14401 C CA . ARG H 1 142 ? 57.745 -77.020 22.624 1.00 172.59 ? 142 ARG H CA 1 +ATOM 14402 C C . ARG H 1 142 ? 57.716 -78.437 22.076 1.00 212.93 ? 142 ARG H C 1 +ATOM 14403 O O . ARG H 1 142 ? 56.827 -78.797 21.300 1.00 250.16 ? 142 ARG H O 1 +ATOM 14404 C CB . ARG H 1 142 ? 56.937 -76.921 23.920 1.00 160.95 ? 142 ARG H CB 1 +ATOM 14405 C CG . ARG H 1 142 ? 57.506 -77.788 25.039 1.00 169.21 ? 142 ARG H CG 1 +ATOM 14406 C CD . ARG H 1 142 ? 57.502 -77.089 26.385 1.00 161.06 ? 142 ARG H CD 1 +ATOM 14407 N NE . ARG H 1 142 ? 56.200 -77.194 27.031 1.00 169.97 ? 142 ARG H NE 1 +ATOM 14408 C CZ . ARG H 1 142 ? 55.726 -76.342 27.936 1.00 178.93 ? 142 ARG H CZ 1 +ATOM 14409 N NH1 . ARG H 1 142 ? 56.448 -75.293 28.313 1.00 203.52 ? 142 ARG H NH1 1 +ATOM 14410 N NH2 . ARG H 1 142 ? 54.516 -76.529 28.461 1.00 148.99 ? 142 ARG H NH2 1 +ATOM 14411 N N . TYR H 1 143 ? 58.730 -79.218 22.441 1.00 229.15 ? 143 TYR H N 1 +ATOM 14412 C CA . TYR H 1 143 ? 58.945 -80.546 21.859 1.00 181.17 ? 143 TYR H CA 1 +ATOM 14413 C C . TYR H 1 143 ? 59.175 -81.600 22.943 1.00 132.45 ? 143 TYR H C 1 +ATOM 14414 O O . TYR H 1 143 ? 60.313 -81.909 23.301 1.00 85.93 ? 143 TYR H O 1 +ATOM 14415 C CB . TYR H 1 143 ? 60.134 -80.490 20.906 1.00 184.80 ? 143 TYR H CB 1 +ATOM 14416 C CG . TYR H 1 143 ? 60.363 -81.728 20.115 1.00 199.54 ? 143 TYR H CG 1 +ATOM 14417 C CD1 . TYR H 1 143 ? 59.522 -82.060 19.055 1.00 206.65 ? 143 TYR H CD1 1 +ATOM 14418 C CD2 . TYR H 1 143 ? 61.470 -82.521 20.354 1.00 201.68 ? 143 TYR H CD2 1 +ATOM 14419 C CE1 . TYR H 1 143 ? 59.767 -83.166 18.265 1.00 201.62 ? 143 TYR H CE1 1 +ATOM 14420 C CE2 . TYR H 1 143 ? 61.727 -83.632 19.566 1.00 220.23 ? 143 TYR H CE2 1 +ATOM 14421 C CZ . TYR H 1 143 ? 60.870 -83.951 18.527 1.00 211.30 ? 143 TYR H CZ 1 +ATOM 14422 O OH . TYR H 1 143 ? 61.118 -85.058 17.749 1.00 195.25 ? 143 TYR H OH 1 +ATOM 14423 N N . GLY H 1 145 ? 59.674 -81.898 25.635 1.00 99.43 ? 145 GLY H N 1 +ATOM 14424 C CA . GLY H 1 145 ? 60.266 -81.437 26.888 1.00 141.11 ? 145 GLY H CA 1 +ATOM 14425 C C . GLY H 1 145 ? 60.953 -80.078 26.846 1.00 164.10 ? 145 GLY H C 1 +ATOM 14426 O O . GLY H 1 145 ? 61.027 -79.396 27.867 1.00 184.14 ? 145 GLY H O 1 +ATOM 14427 N N . ILE H 1 146 ? 61.399 -79.652 25.660 1.00 168.64 ? 146 ILE H N 1 +ATOM 14428 C CA . ILE H 1 146 ? 62.198 -78.418 25.512 1.00 169.32 ? 146 ILE H CA 1 +ATOM 14429 C C . ILE H 1 146 ? 61.410 -77.397 24.690 1.00 172.84 ? 146 ILE H C 1 +ATOM 14430 O O . ILE H 1 146 ? 60.759 -77.755 23.717 1.00 194.22 ? 146 ILE H O 1 +ATOM 14431 C CB . ILE H 1 146 ? 63.552 -78.682 24.809 1.00 174.95 ? 146 ILE H CB 1 +ATOM 14432 C CG1 . ILE H 1 146 ? 64.161 -80.002 25.295 1.00 190.47 ? 146 ILE H CG1 1 +ATOM 14433 C CG2 . ILE H 1 146 ? 64.524 -77.536 25.055 1.00 168.28 ? 146 ILE H CG2 1 +ATOM 14434 C CD1 . ILE H 1 146 ? 63.884 -81.182 24.382 1.00 193.44 ? 146 ILE H CD1 1 +ATOM 14435 N N . GLY H 1 147 ? 61.423 -76.133 25.100 1.00 181.89 ? 147 GLY H N 1 +ATOM 14436 C CA . GLY H 1 147 ? 60.588 -75.132 24.430 1.00 178.65 ? 147 GLY H CA 1 +ATOM 14437 C C . GLY H 1 147 ? 61.128 -73.720 24.445 1.00 165.38 ? 147 GLY H C 1 +ATOM 14438 O O . GLY H 1 147 ? 61.874 -73.338 25.341 1.00 154.21 ? 147 GLY H O 1 +ATOM 14439 N N . ALA H 1 148 ? 60.733 -72.944 23.444 1.00 153.52 ? 148 ALA H N 1 +ATOM 14440 C CA . ALA H 1 148 ? 61.056 -71.532 23.405 1.00 145.69 ? 148 ALA H CA 1 +ATOM 14441 C C . ALA H 1 148 ? 59.943 -70.754 22.710 1.00 143.47 ? 148 ALA H C 1 +ATOM 14442 O O . ALA H 1 148 ? 59.040 -71.326 22.109 1.00 135.08 ? 148 ALA H O 1 +ATOM 14443 C CB . ALA H 1 148 ? 62.390 -71.304 22.707 1.00 123.08 ? 148 ALA H CB 1 +ATOM 14444 N N . ASP H 1 149 ? 59.967 -69.441 22.890 1.00 168.47 ? 149 ASP H N 1 +ATOM 14445 C CA . ASP H 1 149 ? 58.966 -68.574 22.280 1.00 142.78 ? 149 ASP H CA 1 +ATOM 14446 C C . ASP H 1 149 ? 59.413 -67.120 22.326 1.00 127.90 ? 149 ASP H C 1 +ATOM 14447 O O . ASP H 1 149 ? 60.135 -66.713 23.246 1.00 112.07 ? 149 ASP H O 1 +ATOM 14448 C CB . ASP H 1 149 ? 57.605 -68.732 22.967 1.00 157.74 ? 149 ASP H CB 1 +ATOM 14449 C CG . ASP H 1 149 ? 57.504 -67.943 24.243 1.00 179.81 ? 149 ASP H CG 1 +ATOM 14450 O OD1 . ASP H 1 149 ? 58.085 -68.385 25.253 1.00 205.31 ? 149 ASP H OD1 1 +ATOM 14451 O OD2 . ASP H 1 149 ? 56.833 -66.892 24.235 1.00 179.68 ? 149 ASP H OD2 1 +ATOM 14452 N N . THR H 1 150 ? 59.054 -66.364 21.296 1.00 138.04 ? 150 THR H N 1 +ATOM 14453 C CA . THR H 1 150 ? 59.179 -64.918 21.363 1.00 158.62 ? 150 THR H CA 1 +ATOM 14454 C C . THR H 1 150 ? 57.822 -64.275 21.131 1.00 189.95 ? 150 THR H C 1 +ATOM 14455 O O . THR H 1 150 ? 56.928 -64.870 20.525 1.00 235.04 ? 150 THR H O 1 +ATOM 14456 C CB . THR H 1 150 ? 60.184 -64.353 20.335 1.00 151.27 ? 150 THR H CB 1 +ATOM 14457 O OG1 . THR H 1 150 ? 59.766 -64.704 19.015 1.00 117.75 ? 150 THR H OG1 1 +ATOM 14458 C CG2 . THR H 1 150 ? 61.585 -64.878 20.600 1.00 143.31 ? 150 THR H CG2 1 +ATOM 14459 N N . GLN H 1 151 ? 57.666 -63.077 21.673 1.00 191.15 ? 151 GLN H N 1 +ATOM 14460 C CA . GLN H 1 151 ? 56.480 -62.269 21.457 1.00 161.21 ? 151 GLN H CA 1 +ATOM 14461 C C . GLN H 1 151 ? 56.906 -60.839 21.246 1.00 150.46 ? 151 GLN H C 1 +ATOM 14462 O O . GLN H 1 151 ? 57.883 -60.405 21.840 1.00 196.43 ? 151 GLN H O 1 +ATOM 14463 C CB . GLN H 1 151 ? 55.582 -62.359 22.675 1.00 138.78 ? 151 GLN H CB 1 +ATOM 14464 C CG . GLN H 1 151 ? 54.897 -63.701 22.793 1.00 153.29 ? 151 GLN H CG 1 +ATOM 14465 C CD . GLN H 1 151 ? 54.460 -63.981 24.206 1.00 171.25 ? 151 GLN H CD 1 +ATOM 14466 O OE1 . GLN H 1 151 ? 53.966 -63.086 24.888 1.00 186.81 ? 151 GLN H OE1 1 +ATOM 14467 N NE2 . GLN H 1 151 ? 54.631 -65.224 24.657 1.00 171.41 ? 151 GLN H NE2 1 +ATOM 14468 N N . TYR H 1 152 ? 56.239 -60.129 20.343 1.00 128.31 ? 152 TYR H N 1 +ATOM 14469 C CA . TYR H 1 152 ? 56.610 -58.751 20.079 1.00 111.39 ? 152 TYR H CA 1 +ATOM 14470 C C . TYR H 1 152 ? 55.394 -57.871 19.958 1.00 107.52 ? 152 TYR H C 1 +ATOM 14471 O O . TYR H 1 152 ? 54.353 -58.293 19.460 1.00 131.12 ? 152 TYR H O 1 +ATOM 14472 C CB . TYR H 1 152 ? 57.515 -58.643 18.838 1.00 89.32 ? 152 TYR H CB 1 +ATOM 14473 C CG . TYR H 1 152 ? 56.886 -58.111 17.573 1.00 72.65 ? 152 TYR H CG 1 +ATOM 14474 C CD1 . TYR H 1 152 ? 55.873 -58.807 16.917 1.00 84.66 ? 152 TYR H CD1 1 +ATOM 14475 C CD2 . TYR H 1 152 ? 57.374 -56.958 16.972 1.00 64.07 ? 152 TYR H CD2 1 +ATOM 14476 C CE1 . TYR H 1 152 ? 55.319 -58.324 15.721 1.00 94.95 ? 152 TYR H CE1 1 +ATOM 14477 C CE2 . TYR H 1 152 ? 56.844 -56.468 15.771 1.00 68.79 ? 152 TYR H CE2 1 +ATOM 14478 C CZ . TYR H 1 152 ? 55.820 -57.154 15.138 1.00 90.61 ? 152 TYR H CZ 1 +ATOM 14479 O OH . TYR H 1 152 ? 55.292 -56.684 13.947 1.00 87.07 ? 152 TYR H OH 1 +ATOM 14480 N N . GLN H 1 153 ? 55.528 -56.632 20.417 1.00 115.81 ? 153 GLN H N 1 +ATOM 14481 C CA . GLN H 1 153 ? 54.528 -55.606 20.139 1.00 114.30 ? 153 GLN H CA 1 +ATOM 14482 C C . GLN H 1 153 ? 55.209 -54.313 19.684 1.00 93.73 ? 153 GLN H C 1 +ATOM 14483 O O . GLN H 1 153 ? 56.368 -54.057 20.046 1.00 121.67 ? 153 GLN H O 1 +ATOM 14484 C CB . GLN H 1 153 ? 53.682 -55.378 21.389 1.00 118.19 ? 153 GLN H CB 1 +ATOM 14485 C CG . GLN H 1 153 ? 52.831 -56.578 21.815 1.00 143.39 ? 153 GLN H CG 1 +ATOM 14486 C CD . GLN H 1 153 ? 52.089 -56.302 23.130 1.00 188.23 ? 153 GLN H CD 1 +ATOM 14487 O OE1 . GLN H 1 153 ? 52.502 -55.448 23.924 1.00 225.29 ? 153 GLN H OE1 1 +ATOM 14488 N NE2 . GLN H 1 153 ? 51.020 -57.054 23.384 1.00 213.75 ? 153 GLN H NE2 1 +ATOM 14489 N N . LEU H 1 154 ? 54.510 -53.511 18.889 1.00 64.93 ? 154 LEU H N 1 +ATOM 14490 C CA . LEU H 1 154 ? 55.005 -52.182 18.597 1.00 84.68 ? 154 LEU H CA 1 +ATOM 14491 C C . LEU H 1 154 ? 53.926 -51.093 18.554 1.00 107.24 ? 154 LEU H C 1 +ATOM 14492 O O . LEU H 1 154 ? 52.788 -51.331 18.125 1.00 106.41 ? 154 LEU H O 1 +ATOM 14493 C CB . LEU H 1 154 ? 55.786 -52.192 17.303 1.00 76.50 ? 154 LEU H CB 1 +ATOM 14494 C CG . LEU H 1 154 ? 54.949 -52.362 16.052 1.00 92.57 ? 154 LEU H CG 1 +ATOM 14495 C CD1 . LEU H 1 154 ? 54.625 -51.016 15.415 1.00 82.36 ? 154 LEU H CD1 1 +ATOM 14496 C CD2 . LEU H 1 154 ? 55.686 -53.264 15.073 1.00 133.03 ? 154 LEU H CD2 1 +ATOM 14497 N N . ASP H 1 155 ? 54.348 -49.883 18.950 1.00 121.71 ? 155 ASP H N 1 +ATOM 14498 C CA . ASP H 1 155 ? 53.479 -48.729 19.199 1.00 95.80 ? 155 ASP H CA 1 +ATOM 14499 C C . ASP H 1 155 ? 53.924 -47.569 18.302 1.00 83.20 ? 155 ASP H C 1 +ATOM 14500 O O . ASP H 1 155 ? 55.032 -47.583 17.794 1.00 54.96 ? 155 ASP H O 1 +ATOM 14501 C CB . ASP H 1 155 ? 53.588 -48.299 20.669 1.00 92.37 ? 155 ASP H CB 1 +ATOM 14502 C CG . ASP H 1 155 ? 53.495 -49.478 21.636 1.00 102.77 ? 155 ASP H CG 1 +ATOM 14503 O OD1 . ASP H 1 155 ? 54.508 -50.174 21.832 1.00 104.31 ? 155 ASP H OD1 1 +ATOM 14504 O OD2 . ASP H 1 155 ? 52.410 -49.693 22.212 1.00 125.34 ? 155 ASP H OD2 1 +ATOM 14505 N N . GLN H 1 156 ? 53.054 -46.582 18.102 1.00 102.47 ? 156 GLN H N 1 +ATOM 14506 C CA . GLN H 1 156 ? 53.378 -45.442 17.237 1.00 89.25 ? 156 GLN H CA 1 +ATOM 14507 C C . GLN H 1 156 ? 53.379 -44.150 18.020 1.00 92.28 ? 156 GLN H C 1 +ATOM 14508 O O . GLN H 1 156 ? 52.745 -44.037 19.084 1.00 113.44 ? 156 GLN H O 1 +ATOM 14509 C CB . GLN H 1 156 ? 52.386 -45.346 16.092 1.00 97.66 ? 156 GLN H CB 1 +ATOM 14510 C CG . GLN H 1 156 ? 52.798 -44.380 15.007 1.00 95.51 ? 156 GLN H CG 1 +ATOM 14511 C CD . GLN H 1 156 ? 52.100 -44.670 13.679 1.00 132.73 ? 156 GLN H CD 1 +ATOM 14512 O OE1 . GLN H 1 156 ? 51.165 -45.491 13.600 1.00 141.81 ? 156 GLN H OE1 1 +ATOM 14513 N NE2 . GLN H 1 156 ? 52.530 -43.980 12.625 1.00 126.16 ? 156 GLN H NE2 1 +ATOM 14514 N N . ILE H 1 157 ? 54.111 -43.175 17.513 1.00 85.73 ? 157 ILE H N 1 +ATOM 14515 C CA . ILE H 1 157 ? 54.162 -41.855 18.135 1.00 95.57 ? 157 ILE H CA 1 +ATOM 14516 C C . ILE H 1 157 ? 54.477 -40.815 17.051 1.00 87.80 ? 157 ILE H C 1 +ATOM 14517 O O . ILE H 1 157 ? 55.221 -41.093 16.114 1.00 52.25 ? 157 ILE H O 1 +ATOM 14518 C CB . ILE H 1 157 ? 55.228 -41.789 19.245 1.00 103.70 ? 157 ILE H CB 1 +ATOM 14519 C CG1 . ILE H 1 157 ? 54.897 -40.675 20.248 1.00 134.33 ? 157 ILE H CG1 1 +ATOM 14520 C CG2 . ILE H 1 157 ? 56.607 -41.554 18.638 1.00 109.01 ? 157 ILE H CG2 1 +ATOM 14521 C CD1 . ILE H 1 157 ? 55.801 -40.647 21.471 1.00 145.70 ? 157 ILE H CD1 1 +ATOM 14522 N N . ALA H 1 158 ? 53.779 -39.680 17.092 1.00 93.23 ? 158 ALA H N 1 +ATOM 14523 C CA . ALA H 1 158 ? 53.899 -38.717 16.004 1.00 84.59 ? 158 ALA H CA 1 +ATOM 14524 C C . ALA H 1 158 ? 54.014 -37.357 16.578 1.00 63.68 ? 158 ALA H C 1 +ATOM 14525 O O . ALA H 1 158 ? 53.509 -37.092 17.675 1.00 71.25 ? 158 ALA H O 1 +ATOM 14526 C CB . ALA H 1 158 ? 52.726 -38.794 15.016 1.00 87.75 ? 158 ALA H CB 1 +ATOM 14527 N N . VAL H 1 159 ? 54.713 -36.501 15.844 1.00 54.28 ? 159 VAL H N 1 +ATOM 14528 C CA . VAL H 1 159 ? 55.027 -35.182 16.338 1.00 67.56 ? 159 VAL H CA 1 +ATOM 14529 C C . VAL H 1 159 ? 54.881 -34.159 15.245 1.00 74.90 ? 159 VAL H C 1 +ATOM 14530 O O . VAL H 1 159 ? 55.389 -34.333 14.137 1.00 77.19 ? 159 VAL H O 1 +ATOM 14531 C CB . VAL H 1 159 ? 56.444 -35.122 16.917 1.00 93.53 ? 159 VAL H CB 1 +ATOM 14532 C CG1 . VAL H 1 159 ? 56.960 -33.694 16.974 1.00 98.24 ? 159 VAL H CG1 1 +ATOM 14533 C CG2 . VAL H 1 159 ? 56.488 -35.749 18.314 1.00 104.16 ? 159 VAL H CG2 1 +ATOM 14534 N N . ASN H 1 160 ? 54.125 -33.107 15.553 1.00 90.35 ? 160 ASN H N 1 +ATOM 14535 C CA . ASN H 1 160 ? 54.037 -31.947 14.684 1.00 81.57 ? 160 ASN H CA 1 +ATOM 14536 C C . ASN H 1 160 ? 55.002 -30.891 15.199 1.00 75.08 ? 160 ASN H C 1 +ATOM 14537 O O . ASN H 1 160 ? 55.044 -30.605 16.394 1.00 82.54 ? 160 ASN H O 1 +ATOM 14538 C CB . ASN H 1 160 ? 52.619 -31.406 14.685 1.00 92.34 ? 160 ASN H CB 1 +ATOM 14539 C CG . ASN H 1 160 ? 52.468 -30.139 13.835 1.00 131.51 ? 160 ASN H CG 1 +ATOM 14540 O OD1 . ASN H 1 160 ? 53.206 -29.167 14.000 1.00 171.47 ? 160 ASN H OD1 1 +ATOM 14541 N ND2 . ASN H 1 160 ? 51.400 -30.081 13.056 1.00 146.34 ? 160 ASN H ND2 1 +ATOM 14542 N N . LEU H 1 161 ? 55.831 -30.377 14.307 1.00 66.49 ? 161 LEU H N 1 +ATOM 14543 C CA . LEU H 1 161 ? 56.527 -29.138 14.562 1.00 67.16 ? 161 LEU H CA 1 +ATOM 14544 C C . LEU H 1 161 ? 56.225 -28.138 13.453 1.00 74.67 ? 161 LEU H C 1 +ATOM 14545 O O . LEU H 1 161 ? 56.030 -28.498 12.302 1.00 73.32 ? 161 LEU H O 1 +ATOM 14546 C CB . LEU H 1 161 ? 58.029 -29.376 14.614 1.00 67.84 ? 161 LEU H CB 1 +ATOM 14547 C CG . LEU H 1 161 ? 58.513 -30.262 15.735 1.00 71.66 ? 161 LEU H CG 1 +ATOM 14548 C CD1 . LEU H 1 161 ? 59.994 -30.555 15.557 1.00 99.09 ? 161 LEU H CD1 1 +ATOM 14549 C CD2 . LEU H 1 161 ? 58.265 -29.559 17.061 1.00 91.98 ? 161 LEU H CD2 1 +ATOM 14550 N N . ARG H 1 162 ? 56.198 -26.864 13.787 1.00 91.41 ? 162 ARG H N 1 +ATOM 14551 C CA . ARG H 1 162 ? 55.881 -25.864 12.781 1.00 109.35 ? 162 ARG H CA 1 +ATOM 14552 C C . ARG H 1 162 ? 56.458 -24.486 13.072 1.00 90.18 ? 162 ARG H C 1 +ATOM 14553 O O . ARG H 1 162 ? 56.346 -23.958 14.174 1.00 106.13 ? 162 ARG H O 1 +ATOM 14554 C CB . ARG H 1 162 ? 54.363 -25.790 12.536 1.00 139.03 ? 162 ARG H CB 1 +ATOM 14555 C CG . ARG H 1 162 ? 53.493 -25.348 13.704 1.00 150.27 ? 162 ARG H CG 1 +ATOM 14556 C CD . ARG H 1 162 ? 52.109 -24.944 13.203 1.00 139.78 ? 162 ARG H CD 1 +ATOM 14557 N NE . ARG H 1 162 ? 51.283 -24.333 14.250 1.00 130.31 ? 162 ARG H NE 1 +ATOM 14558 C CZ . ARG H 1 162 ? 50.583 -25.006 15.170 1.00 116.35 ? 162 ARG H CZ 1 +ATOM 14559 N NH1 . ARG H 1 162 ? 50.619 -26.331 15.219 1.00 100.87 ? 162 ARG H NH1 1 +ATOM 14560 N NH2 . ARG H 1 162 ? 49.870 -24.338 16.064 1.00 103.06 ? 162 ARG H NH2 1 +ATOM 14561 N N . VAL H 1 163 ? 57.086 -23.931 12.048 1.00 91.34 ? 163 VAL H N 1 +ATOM 14562 C CA . VAL H 1 163 ? 57.682 -22.604 12.109 1.00 110.63 ? 163 VAL H CA 1 +ATOM 14563 C C . VAL H 1 163 ? 56.610 -21.580 11.810 1.00 115.91 ? 163 VAL H C 1 +ATOM 14564 O O . VAL H 1 163 ? 56.076 -21.539 10.702 1.00 147.67 ? 163 VAL H O 1 +ATOM 14565 C CB . VAL H 1 163 ? 58.809 -22.404 11.051 1.00 110.05 ? 163 VAL H CB 1 +ATOM 14566 C CG1 . VAL H 1 163 ? 59.384 -20.983 11.129 1.00 90.12 ? 163 VAL H CG1 1 +ATOM 14567 C CG2 . VAL H 1 163 ? 59.877 -23.482 11.220 1.00 109.36 ? 163 VAL H CG2 1 +ATOM 14568 N N . VAL H 1 164 ? 56.449 -20.657 12.743 1.00 101.42 ? 164 VAL H N 1 +ATOM 14569 C CA . VAL H 1 164 ? 55.558 -19.545 12.566 1.00 85.45 ? 164 VAL H CA 1 +ATOM 14570 C C . VAL H 1 164 ? 56.376 -18.284 12.449 1.00 71.97 ? 164 VAL H C 1 +ATOM 14571 O O . VAL H 1 164 ? 57.273 -18.022 13.278 1.00 87.84 ? 164 VAL H O 1 +ATOM 14572 C CB . VAL H 1 164 ? 54.630 -19.433 13.774 1.00 128.56 ? 164 VAL H CB 1 +ATOM 14573 C CG1 . VAL H 1 164 ? 53.704 -18.230 13.633 1.00 163.97 ? 164 VAL H CG1 1 +ATOM 14574 C CG2 . VAL H 1 164 ? 53.828 -20.719 13.923 1.00 107.17 ? 164 VAL H CG2 1 +ATOM 14575 N N . ASN H 1 165 ? 55.997 -17.455 11.495 1.00 64.32 ? 165 ASN H N 1 +ATOM 14576 C CA . ASN H 1 165 ? 56.596 -16.137 11.393 1.00 95.72 ? 165 ASN H CA 1 +ATOM 14577 C C . ASN H 1 165 ? 55.986 -15.115 12.360 1.00 104.80 ? 165 ASN H C 1 +ATOM 14578 O O . ASN H 1 165 ? 54.806 -14.764 12.228 1.00 139.74 ? 165 ASN H O 1 +ATOM 14579 C CB . ASN H 1 165 ? 56.457 -15.592 9.975 1.00 103.41 ? 165 ASN H CB 1 +ATOM 14580 C CG . ASN H 1 165 ? 57.180 -14.274 9.802 1.00 94.91 ? 165 ASN H CG 1 +ATOM 14581 O OD1 . ASN H 1 165 ? 58.157 -14.008 10.543 1.00 142.38 ? 165 ASN H OD1 1 +ATOM 14582 N ND2 . ASN H 1 165 ? 56.929 -13.629 8.672 1.00 88.58 ? 165 ASN H ND2 1 +ATOM 14583 N N . VAL H 1 166 ? 56.811 -14.594 13.268 1.00 83.94 ? 166 VAL H N 1 +ATOM 14584 C CA . VAL H 1 166 ? 56.372 -13.628 14.238 1.00 66.09 ? 166 VAL H CA 1 +ATOM 14585 C C . VAL H 1 166 ? 55.813 -12.414 13.536 1.00 74.42 ? 166 VAL H C 1 +ATOM 14586 O O . VAL H 1 166 ? 54.824 -11.828 14.015 1.00 159.38 ? 166 VAL H O 1 +ATOM 14587 C CB . VAL H 1 166 ? 57.527 -13.213 15.155 1.00 88.70 ? 166 VAL H CB 1 +ATOM 14588 C CG1 . VAL H 1 166 ? 57.307 -11.828 15.792 1.00 101.16 ? 166 VAL H CG1 1 +ATOM 14589 C CG2 . VAL H 1 166 ? 57.763 -14.294 16.210 1.00 95.41 ? 166 VAL H CG2 1 +ATOM 14590 N N . SER H 1 167 ? 56.417 -12.024 12.409 1.00 63.79 ? 167 SER H N 1 +ATOM 14591 C CA . SER H 1 167 ? 56.130 -10.728 11.804 1.00 72.73 ? 167 SER H CA 1 +ATOM 14592 C C . SER H 1 167 ? 54.796 -10.725 11.062 1.00 99.93 ? 167 SER H C 1 +ATOM 14593 O O . SER H 1 167 ? 54.237 -9.651 10.773 1.00 83.13 ? 167 SER H O 1 +ATOM 14594 C CB . SER H 1 167 ? 57.244 -10.340 10.853 1.00 65.17 ? 167 SER H CB 1 +ATOM 14595 O OG . SER H 1 167 ? 58.512 -10.500 11.470 1.00 70.05 ? 167 SER H OG 1 +ATOM 14596 N N . THR H 1 168 ? 54.227 -11.918 10.854 1.00 118.43 ? 168 THR H N 1 +ATOM 14597 C CA . THR H 1 168 ? 52.922 -12.038 10.168 1.00 101.48 ? 168 THR H CA 1 +ATOM 14598 C C . THR H 1 168 ? 51.918 -13.010 10.818 1.00 88.08 ? 168 THR H C 1 +ATOM 14599 O O . THR H 1 168 ? 50.698 -12.846 10.715 1.00 100.24 ? 168 THR H O 1 +ATOM 14600 C CB . THR H 1 168 ? 53.157 -12.479 8.721 1.00 88.75 ? 168 THR H CB 1 +ATOM 14601 O OG1 . THR H 1 168 ? 53.989 -13.635 8.731 1.00 55.55 ? 168 THR H OG1 1 +ATOM 14602 C CG2 . THR H 1 168 ? 53.823 -11.349 7.933 1.00 100.99 ? 168 THR H CG2 1 +ATOM 14603 N N . GLY H 1 169 ? 52.426 -14.067 11.423 1.00 76.53 ? 169 GLY H N 1 +ATOM 14604 C CA . GLY H 1 169 ? 51.566 -15.133 11.853 1.00 78.57 ? 169 GLY H CA 1 +ATOM 14605 C C . GLY H 1 169 ? 51.428 -16.215 10.802 1.00 88.76 ? 169 GLY H C 1 +ATOM 14606 O O . GLY H 1 169 ? 50.861 -17.280 11.080 1.00 125.44 ? 169 GLY H O 1 +ATOM 14607 N N . GLU H 1 170 ? 51.909 -15.952 9.581 1.00 82.30 ? 170 GLU H N 1 +ATOM 14608 C CA . GLU H 1 170 ? 52.002 -17.009 8.543 1.00 71.95 ? 170 GLU H CA 1 +ATOM 14609 C C . GLU H 1 170 ? 52.794 -18.150 9.136 1.00 62.70 ? 170 GLU H C 1 +ATOM 14610 O O . GLU H 1 170 ? 53.867 -17.941 9.695 1.00 63.17 ? 170 GLU H O 1 +ATOM 14611 C CB . GLU H 1 170 ? 52.699 -16.508 7.259 1.00 72.52 ? 170 GLU H CB 1 +ATOM 14612 C CG . GLU H 1 170 ? 51.837 -15.650 6.342 1.00 76.07 ? 170 GLU H CG 1 +ATOM 14613 C CD . GLU H 1 170 ? 52.579 -14.504 5.652 1.00 77.30 ? 170 GLU H CD 1 +ATOM 14614 O OE1 . GLU H 1 170 ? 53.710 -14.191 6.058 1.00 78.41 ? 170 GLU H OE1 1 +ATOM 14615 O OE2 . GLU H 1 170 ? 51.983 -13.826 4.796 1.00 56.94 ? 170 GLU H OE2 1 +ATOM 14616 N N . ILE H 1 171 ? 52.240 -19.348 9.088 1.00 60.41 ? 171 ILE H N 1 +ATOM 14617 C CA . ILE H 1 171 ? 53.049 -20.507 9.323 1.00 81.94 ? 171 ILE H CA 1 +ATOM 14618 C C . ILE H 1 171 ? 54.006 -20.655 8.131 1.00 98.74 ? 171 ILE H C 1 +ATOM 14619 O O . ILE H 1 171 ? 53.558 -20.715 6.992 1.00 99.16 ? 171 ILE H O 1 +ATOM 14620 C CB . ILE H 1 171 ? 52.173 -21.753 9.485 1.00 80.03 ? 171 ILE H CB 1 +ATOM 14621 C CG1 . ILE H 1 171 ? 51.451 -21.663 10.821 1.00 97.26 ? 171 ILE H CG1 1 +ATOM 14622 C CG2 . ILE H 1 171 ? 53.039 -23.002 9.426 1.00 91.10 ? 171 ILE H CG2 1 +ATOM 14623 C CD1 . ILE H 1 171 ? 50.298 -22.626 10.930 1.00 101.33 ? 171 ILE H CD1 1 +ATOM 14624 N N . LEU H 1 172 ? 55.314 -20.702 8.392 1.00 89.12 ? 172 LEU H N 1 +ATOM 14625 C CA . LEU H 1 172 ? 56.280 -20.813 7.311 1.00 77.41 ? 172 LEU H CA 1 +ATOM 14626 C C . LEU H 1 172 ? 56.621 -22.283 6.950 1.00 100.43 ? 172 LEU H C 1 +ATOM 14627 O O . LEU H 1 172 ? 57.284 -22.572 5.930 1.00 91.87 ? 172 LEU H O 1 +ATOM 14628 C CB . LEU H 1 172 ? 57.557 -20.026 7.640 1.00 72.00 ? 172 LEU H CB 1 +ATOM 14629 C CG . LEU H 1 172 ? 57.663 -18.540 7.244 1.00 73.00 ? 172 LEU H CG 1 +ATOM 14630 C CD1 . LEU H 1 172 ? 56.277 -17.979 7.192 1.00 69.41 ? 172 LEU H CD1 1 +ATOM 14631 C CD2 . LEU H 1 172 ? 58.614 -17.679 8.056 1.00 93.95 ? 172 LEU H CD2 1 +ATOM 14632 N N . SER H 1 173 ? 56.222 -23.213 7.818 1.00 88.54 ? 173 SER H N 1 +ATOM 14633 C CA . SER H 1 173 ? 56.514 -24.640 7.608 1.00 62.68 ? 173 SER H CA 1 +ATOM 14634 C C . SER H 1 173 ? 55.831 -25.501 8.644 1.00 64.66 ? 173 SER H C 1 +ATOM 14635 O O . SER H 1 173 ? 55.888 -25.224 9.856 1.00 113.24 ? 173 SER H O 1 +ATOM 14636 C CB . SER H 1 173 ? 58.015 -24.903 7.721 1.00 73.20 ? 173 SER H CB 1 +ATOM 14637 O OG . SER H 1 173 ? 58.267 -26.284 7.877 1.00 70.39 ? 173 SER H OG 1 +ATOM 14638 N N . SER H 1 174 ? 55.194 -26.556 8.190 1.00 72.60 ? 174 SER H N 1 +ATOM 14639 C CA . SER H 1 174 ? 54.637 -27.552 9.109 1.00 86.73 ? 174 SER H CA 1 +ATOM 14640 C C . SER H 1 174 ? 55.203 -28.877 8.701 1.00 102.78 ? 174 SER H C 1 +ATOM 14641 O O . SER H 1 174 ? 55.236 -29.208 7.506 1.00 150.25 ? 174 SER H O 1 +ATOM 14642 C CB . SER H 1 174 ? 53.082 -27.600 9.060 1.00 93.14 ? 174 SER H CB 1 +ATOM 14643 O OG . SER H 1 174 ? 52.523 -28.415 10.088 1.00 67.06 ? 174 SER H OG 1 +ATOM 14644 N N . VAL H 1 175 ? 55.598 -29.665 9.688 1.00 100.87 ? 175 VAL H N 1 +ATOM 14645 C CA . VAL H 1 175 ? 56.103 -31.006 9.427 1.00 103.59 ? 175 VAL H CA 1 +ATOM 14646 C C . VAL H 1 175 ? 55.517 -32.022 10.391 1.00 103.91 ? 175 VAL H C 1 +ATOM 14647 O O . VAL H 1 175 ? 55.339 -31.736 11.588 1.00 169.21 ? 175 VAL H O 1 +ATOM 14648 C CB . VAL H 1 175 ? 57.648 -31.038 9.497 1.00 115.14 ? 175 VAL H CB 1 +ATOM 14649 C CG1 . VAL H 1 175 ? 58.244 -30.155 8.412 1.00 110.74 ? 175 VAL H CG1 1 +ATOM 14650 C CG2 . VAL H 1 175 ? 58.149 -30.577 10.849 1.00 136.35 ? 175 VAL H CG2 1 +ATOM 14651 N N . ASN H 1 176 ? 55.289 -33.228 9.882 1.00 100.83 ? 176 ASN H N 1 +ATOM 14652 C CA . ASN H 1 176 ? 54.684 -34.306 10.665 1.00 133.19 ? 176 ASN H CA 1 +ATOM 14653 C C . ASN H 1 176 ? 55.529 -35.599 10.724 1.00 131.07 ? 176 ASN H C 1 +ATOM 14654 O O . ASN H 1 176 ? 55.402 -36.435 9.847 1.00 118.98 ? 176 ASN H O 1 +ATOM 14655 C CB . ASN H 1 176 ? 53.310 -34.592 10.055 1.00 122.64 ? 176 ASN H CB 1 +ATOM 14656 C CG . ASN H 1 176 ? 52.190 -33.864 10.796 1.00 110.73 ? 176 ASN H CG 1 +ATOM 14657 O OD1 . ASN H 1 176 ? 52.485 -32.935 11.537 1.00 120.16 ? 176 ASN H OD1 1 +ATOM 14658 N ND2 . ASN H 1 176 ? 50.915 -34.232 10.567 1.00 105.07 ? 176 ASN H ND2 1 +ATOM 14659 N N . THR H 1 177 ? 56.319 -35.784 11.789 1.00 108.98 ? 177 THR H N 1 +ATOM 14660 C CA . THR H 1 177 ? 57.185 -36.953 11.904 1.00 84.87 ? 177 THR H CA 1 +ATOM 14661 C C . THR H 1 177 ? 56.580 -38.032 12.781 1.00 86.63 ? 177 THR H C 1 +ATOM 14662 O O . THR H 1 177 ? 55.638 -37.778 13.532 1.00 114.82 ? 177 THR H O 1 +ATOM 14663 C CB . THR H 1 177 ? 58.548 -36.588 12.495 1.00 96.52 ? 177 THR H CB 1 +ATOM 14664 O OG1 . THR H 1 177 ? 58.413 -36.248 13.877 1.00 90.21 ? 177 THR H OG1 1 +ATOM 14665 C CG2 . THR H 1 177 ? 59.183 -35.403 11.743 1.00 97.52 ? 177 THR H CG2 1 +ATOM 14666 N N . SER H 1 178 ? 57.077 -39.253 12.624 1.00 92.91 ? 178 SER H N 1 +ATOM 14667 C CA . SER H 1 178 ? 56.489 -40.421 13.275 1.00 99.16 ? 178 SER H CA 1 +ATOM 14668 C C . SER H 1 178 ? 57.558 -41.435 13.590 1.00 92.24 ? 178 SER H C 1 +ATOM 14669 O O . SER H 1 178 ? 58.571 -41.553 12.894 1.00 80.02 ? 178 SER H O 1 +ATOM 14670 C CB . SER H 1 178 ? 55.404 -41.083 12.397 1.00 108.76 ? 178 SER H CB 1 +ATOM 14671 O OG . SER H 1 178 ? 55.058 -42.374 12.887 1.00 102.19 ? 178 SER H OG 1 +ATOM 14672 N N . LYS H 1 179 ? 57.306 -42.225 14.616 1.00 109.99 ? 179 LYS H N 1 +ATOM 14673 C CA . LYS H 1 179 ? 58.311 -43.168 15.068 1.00 125.47 ? 179 LYS H CA 1 +ATOM 14674 C C . LYS H 1 179 ? 57.668 -44.337 15.797 1.00 104.81 ? 179 LYS H C 1 +ATOM 14675 O O . LYS H 1 179 ? 56.642 -44.205 16.468 1.00 157.70 ? 179 LYS H O 1 +ATOM 14676 C CB . LYS H 1 179 ? 59.288 -42.439 15.985 1.00 159.17 ? 179 LYS H CB 1 +ATOM 14677 C CG . LYS H 1 179 ? 60.729 -42.902 15.876 1.00 164.79 ? 179 LYS H CG 1 +ATOM 14678 C CD . LYS H 1 179 ? 61.032 -43.947 16.931 1.00 129.78 ? 179 LYS H CD 1 +ATOM 14679 C CE . LYS H 1 179 ? 62.409 -44.525 16.716 1.00 113.43 ? 179 LYS H CE 1 +ATOM 14680 N NZ . LYS H 1 179 ? 62.605 -45.745 17.530 1.00 101.89 ? 179 LYS H NZ 1 +ATOM 14681 N N . THR H 1 180 ? 58.293 -45.486 15.670 1.00 60.09 ? 180 THR H N 1 +ATOM 14682 C CA . THR H 1 180 ? 57.751 -46.681 16.201 1.00 73.50 ? 180 THR H CA 1 +ATOM 14683 C C . THR H 1 180 ? 58.529 -47.143 17.424 1.00 83.29 ? 180 THR H C 1 +ATOM 14684 O O . THR H 1 180 ? 59.749 -47.271 17.373 1.00 83.57 ? 180 THR H O 1 +ATOM 14685 C CB . THR H 1 180 ? 57.968 -47.791 15.166 1.00 86.84 ? 180 THR H CB 1 +ATOM 14686 O OG1 . THR H 1 180 ? 57.607 -47.308 13.874 1.00 58.91 ? 180 THR H OG1 1 +ATOM 14687 C CG2 . THR H 1 180 ? 57.198 -49.064 15.504 1.00 81.69 ? 180 THR H CG2 1 +ATOM 14688 N N . ILE H 1 181 ? 57.799 -47.557 18.455 1.00 99.57 ? 181 ILE H N 1 +ATOM 14689 C CA . ILE H 1 181 ? 58.404 -48.091 19.676 1.00 97.97 ? 181 ILE H CA 1 +ATOM 14690 C C . ILE H 1 181 ? 58.309 -49.630 19.688 1.00 87.71 ? 181 ILE H C 1 +ATOM 14691 O O . ILE H 1 181 ? 57.216 -50.191 19.755 1.00 86.48 ? 181 ILE H O 1 +ATOM 14692 C CB . ILE H 1 181 ? 57.735 -47.473 20.952 1.00 93.46 ? 181 ILE H CB 1 +ATOM 14693 C CG1 . ILE H 1 181 ? 57.715 -45.944 20.860 1.00 83.89 ? 181 ILE H CG1 1 +ATOM 14694 C CG2 . ILE H 1 181 ? 58.460 -47.879 22.223 1.00 86.11 ? 181 ILE H CG2 1 +ATOM 14695 C CD1 . ILE H 1 181 ? 56.324 -45.353 20.871 1.00 82.89 ? 181 ILE H CD1 1 +ATOM 14696 N N . LEU H 1 182 ? 59.466 -50.282 19.678 1.00 84.55 ? 182 LEU H N 1 +ATOM 14697 C CA . LEU H 1 182 ? 59.546 -51.737 19.695 1.00 103.08 ? 182 LEU H CA 1 +ATOM 14698 C C . LEU H 1 182 ? 59.623 -52.368 21.092 1.00 106.22 ? 182 LEU H C 1 +ATOM 14699 O O . LEU H 1 182 ? 60.372 -51.909 21.966 1.00 97.93 ? 182 LEU H O 1 +ATOM 14700 C CB . LEU H 1 182 ? 60.765 -52.183 18.887 1.00 110.28 ? 182 LEU H CB 1 +ATOM 14701 C CG . LEU H 1 182 ? 60.997 -53.700 18.800 1.00 94.04 ? 182 LEU H CG 1 +ATOM 14702 C CD1 . LEU H 1 182 ? 59.853 -54.434 18.120 1.00 96.39 ? 182 LEU H CD1 1 +ATOM 14703 C CD2 . LEU H 1 182 ? 62.303 -53.917 18.066 1.00 93.08 ? 182 LEU H CD2 1 +ATOM 14704 N N . SER H 1 183 ? 58.923 -53.487 21.249 1.00 131.89 ? 183 SER H N 1 +ATOM 14705 C CA . SER H 1 183 ? 59.002 -54.296 22.460 1.00 155.39 ? 183 SER H CA 1 +ATOM 14706 C C . SER H 1 183 ? 59.017 -55.780 22.096 1.00 161.43 ? 183 SER H C 1 +ATOM 14707 O O . SER H 1 183 ? 58.294 -56.210 21.198 1.00 165.30 ? 183 SER H O 1 +ATOM 14708 C CB . SER H 1 183 ? 57.812 -53.992 23.381 1.00 135.92 ? 183 SER H CB 1 +ATOM 14709 O OG . SER H 1 183 ? 57.499 -52.608 23.351 1.00 152.40 ? 183 SER H OG 1 +ATOM 14710 N N . TYR H 1 184 ? 59.819 -56.563 22.814 1.00 176.70 ? 184 TYR H N 1 +ATOM 14711 C CA . TYR H 1 184 ? 59.841 -58.015 22.620 1.00 157.04 ? 184 TYR H CA 1 +ATOM 14712 C C . TYR H 1 184 ? 60.243 -58.824 23.861 1.00 135.77 ? 184 TYR H C 1 +ATOM 14713 O O . TYR H 1 184 ? 60.924 -58.337 24.773 1.00 126.95 ? 184 TYR H O 1 +ATOM 14714 C CB . TYR H 1 184 ? 60.734 -58.394 21.432 1.00 145.32 ? 184 TYR H CB 1 +ATOM 14715 C CG . TYR H 1 184 ? 62.177 -57.957 21.562 1.00 138.57 ? 184 TYR H CG 1 +ATOM 14716 C CD1 . TYR H 1 184 ? 63.109 -58.724 22.271 1.00 90.87 ? 184 TYR H CD1 1 +ATOM 14717 C CD2 . TYR H 1 184 ? 62.613 -56.780 20.968 1.00 133.74 ? 184 TYR H CD2 1 +ATOM 14718 C CE1 . TYR H 1 184 ? 64.422 -58.329 22.379 1.00 69.26 ? 184 TYR H CE1 1 +ATOM 14719 C CE2 . TYR H 1 184 ? 63.930 -56.383 21.075 1.00 117.25 ? 184 TYR H CE2 1 +ATOM 14720 C CZ . TYR H 1 184 ? 64.831 -57.173 21.763 1.00 84.52 ? 184 TYR H CZ 1 +ATOM 14721 O OH . TYR H 1 184 ? 66.112 -56.706 21.946 1.00 106.96 ? 184 TYR H OH 1 +ATOM 14722 N N . GLU H 1 185 ? 59.777 -60.066 23.875 1.00 136.55 ? 185 GLU H N 1 +ATOM 14723 C CA . GLU H 1 185 ? 59.982 -60.988 24.990 1.00 170.80 ? 185 GLU H CA 1 +ATOM 14724 C C . GLU H 1 185 ? 60.432 -62.337 24.469 1.00 200.30 ? 185 GLU H C 1 +ATOM 14725 O O . GLU H 1 185 ? 59.654 -63.046 23.835 1.00 250.92 ? 185 GLU H O 1 +ATOM 14726 C CB . GLU H 1 185 ? 58.718 -61.201 25.840 1.00 165.45 ? 185 GLU H CB 1 +ATOM 14727 C CG . GLU H 1 185 ? 57.905 -59.962 26.153 1.00 171.55 ? 185 GLU H CG 1 +ATOM 14728 C CD . GLU H 1 185 ? 56.817 -60.256 27.177 1.00 167.30 ? 185 GLU H CD 1 +ATOM 14729 O OE1 . GLU H 1 185 ? 56.671 -61.431 27.581 1.00 145.48 ? 185 GLU H OE1 1 +ATOM 14730 O OE2 . GLU H 1 185 ? 56.105 -59.311 27.568 1.00 148.89 ? 185 GLU H OE2 1 +ATOM 14731 N N . VAL H 1 186 ? 61.679 -62.686 24.766 1.00 197.22 ? 186 VAL H N 1 +ATOM 14732 C CA . VAL H 1 186 ? 62.239 -63.981 24.407 1.00 163.42 ? 186 VAL H CA 1 +ATOM 14733 C C . VAL H 1 186 ? 62.279 -64.890 25.633 1.00 141.02 ? 186 VAL H C 1 +ATOM 14734 O O . VAL H 1 186 ? 62.574 -64.442 26.741 1.00 142.07 ? 186 VAL H O 1 +ATOM 14735 C CB . VAL H 1 186 ? 63.661 -63.831 23.848 1.00 144.18 ? 186 VAL H CB 1 +ATOM 14736 C CG1 . VAL H 1 186 ? 64.146 -65.157 23.288 1.00 139.86 ? 186 VAL H CG1 1 +ATOM 14737 C CG2 . VAL H 1 186 ? 63.694 -62.753 22.777 1.00 138.89 ? 186 VAL H CG2 1 +ATOM 14738 N N . GLN H 1 187 ? 61.937 -66.157 25.436 1.00 123.85 ? 187 GLN H N 1 +ATOM 14739 C CA . GLN H 1 187 ? 61.816 -67.084 26.547 1.00 151.63 ? 187 GLN H CA 1 +ATOM 14740 C C . GLN H 1 187 ? 62.178 -68.477 26.114 1.00 164.93 ? 187 GLN H C 1 +ATOM 14741 O O . GLN H 1 187 ? 61.737 -68.931 25.058 1.00 240.64 ? 187 GLN H O 1 +ATOM 14742 C CB . GLN H 1 187 ? 60.376 -67.091 27.085 1.00 154.47 ? 187 GLN H CB 1 +ATOM 14743 C CG . GLN H 1 187 ? 60.059 -66.021 28.101 1.00 157.94 ? 187 GLN H CG 1 +ATOM 14744 C CD . GLN H 1 187 ? 58.577 -65.738 28.132 1.00 172.28 ? 187 GLN H CD 1 +ATOM 14745 O OE1 . GLN H 1 187 ? 58.171 -64.624 28.431 1.00 202.30 ? 187 GLN H OE1 1 +ATOM 14746 N NE2 . GLN H 1 187 ? 57.759 -66.737 27.771 1.00 169.30 ? 187 GLN H NE2 1 +ATOM 14747 N N . ALA H 1 188 ? 62.906 -69.180 26.973 1.00 170.75 ? 188 ALA H N 1 +ATOM 14748 C CA . ALA H 1 188 ? 63.225 -70.576 26.716 1.00 149.77 ? 188 ALA H CA 1 +ATOM 14749 C C . ALA H 1 188 ? 63.166 -71.388 28.010 1.00 148.76 ? 188 ALA H C 1 +ATOM 14750 O O . ALA H 1 188 ? 63.535 -70.899 29.070 1.00 142.37 ? 188 ALA H O 1 +ATOM 14751 C CB . ALA H 1 188 ? 64.593 -70.679 26.067 1.00 116.88 ? 188 ALA H CB 1 +ATOM 14752 N N . GLY H 1 189 ? 62.647 -72.605 27.927 1.00 146.89 ? 189 GLY H N 1 +ATOM 14753 C CA . GLY H 1 189 ? 62.537 -73.468 29.089 1.00 157.29 ? 189 GLY H CA 1 +ATOM 14754 C C . GLY H 1 189 ? 62.794 -74.921 28.753 1.00 193.08 ? 189 GLY H C 1 +ATOM 14755 O O . GLY H 1 189 ? 62.329 -75.422 27.732 1.00 204.98 ? 189 GLY H O 1 +ATOM 14756 N N . VAL H 1 190 ? 63.536 -75.599 29.622 1.00 225.18 ? 190 VAL H N 1 +ATOM 14757 C CA . VAL H 1 190 ? 63.801 -77.023 29.469 1.00 209.43 ? 190 VAL H CA 1 +ATOM 14758 C C . VAL H 1 190 ? 63.138 -77.802 30.617 1.00 214.82 ? 190 VAL H C 1 +ATOM 14759 O O . VAL H 1 190 ? 63.222 -77.395 31.784 1.00 232.65 ? 190 VAL H O 1 +ATOM 14760 C CB . VAL H 1 190 ? 65.320 -77.299 29.440 1.00 171.58 ? 190 VAL H CB 1 +ATOM 14761 C CG1 . VAL H 1 190 ? 65.578 -78.734 29.029 1.00 172.83 ? 190 VAL H CG1 1 +ATOM 14762 C CG2 . VAL H 1 190 ? 66.035 -76.321 28.508 1.00 133.12 ? 190 VAL H CG2 1 +ATOM 14763 N N . PHE H 1 191 ? 62.478 -78.910 30.282 1.00 202.08 ? 191 PHE H N 1 +ATOM 14764 C CA . PHE H 1 191 ? 61.648 -79.644 31.248 1.00 212.72 ? 191 PHE H CA 1 +ATOM 14765 C C . PHE H 1 191 ? 61.883 -81.172 31.124 1.00 261.31 ? 191 PHE H C 1 +ATOM 14766 O O . PHE H 1 191 ? 61.944 -81.692 30.041 1.00 299.14 ? 191 PHE H O 1 +ATOM 14767 C CB . PHE H 1 191 ? 60.167 -79.334 30.975 1.00 175.87 ? 191 PHE H CB 1 +ATOM 14768 C CG . PHE H 1 191 ? 59.255 -79.604 32.146 1.00 178.75 ? 191 PHE H CG 1 +ATOM 14769 C CD1 . PHE H 1 191 ? 58.939 -80.910 32.520 1.00 140.81 ? 191 PHE H CD1 1 +ATOM 14770 C CD2 . PHE H 1 191 ? 58.687 -78.557 32.852 1.00 202.15 ? 191 PHE H CD2 1 +ATOM 14771 C CE1 . PHE H 1 191 ? 58.111 -81.164 33.594 1.00 118.00 ? 191 PHE H CE1 1 +ATOM 14772 C CE2 . PHE H 1 191 ? 57.821 -78.808 33.907 1.00 194.35 ? 191 PHE H CE2 1 +ATOM 14773 C CZ . PHE H 1 191 ? 57.541 -80.113 34.282 1.00 152.57 ? 191 PHE H CZ 1 +ATOM 14774 N N . ARG H 1 192 ? 61.948 -81.905 32.233 1.00 251.60 ? 192 ARG H N 1 +ATOM 14775 C CA . ARG H 1 192 ? 62.089 -83.375 32.187 1.00 193.49 ? 192 ARG H CA 1 +ATOM 14776 C C . ARG H 1 192 ? 61.627 -84.011 33.505 1.00 159.62 ? 192 ARG H C 1 +ATOM 14777 O O . ARG H 1 192 ? 61.373 -85.210 33.581 1.00 110.71 ? 192 ARG H O 1 +ATOM 14778 C CB . ARG H 1 192 ? 63.544 -83.757 31.867 1.00 171.43 ? 192 ARG H CB 1 +ATOM 14779 C CG . ARG H 1 192 ? 63.793 -84.180 30.422 1.00 154.84 ? 192 ARG H CG 1 +ATOM 14780 C CD . ARG H 1 192 ? 65.142 -83.712 29.904 1.00 158.11 ? 192 ARG H CD 1 +ATOM 14781 N NE . ARG H 1 192 ? 65.222 -83.754 28.447 1.00 169.31 ? 192 ARG H NE 1 +ATOM 14782 C CZ . ARG H 1 192 ? 65.749 -82.807 27.671 1.00 144.24 ? 192 ARG H CZ 1 +ATOM 14783 N NH1 . ARG H 1 192 ? 66.202 -81.681 28.200 1.00 142.02 ? 192 ARG H NH1 1 +ATOM 14784 N NH2 . ARG H 1 192 ? 65.876 -83.015 26.365 1.00 113.99 ? 192 ARG H NH2 1 +ATOM 14785 N N . LEU H 1 200 ? 63.775 -82.185 36.607 1.00 88.13 ? 200 LEU H N 1 +ATOM 14786 C CA . LEU H 1 200 ? 64.537 -81.087 36.023 1.00 138.98 ? 200 LEU H CA 1 +ATOM 14787 C C . LEU H 1 200 ? 63.631 -80.101 35.296 1.00 173.64 ? 200 LEU H C 1 +ATOM 14788 O O . LEU H 1 200 ? 63.079 -80.409 34.230 1.00 196.86 ? 200 LEU H O 1 +ATOM 14789 C CB . LEU H 1 200 ? 65.617 -81.572 35.036 1.00 149.84 ? 200 LEU H CB 1 +ATOM 14790 C CG . LEU H 1 200 ? 66.328 -80.440 34.249 1.00 147.62 ? 200 LEU H CG 1 +ATOM 14791 C CD1 . LEU H 1 200 ? 67.686 -80.143 34.873 1.00 135.71 ? 200 LEU H CD1 1 +ATOM 14792 C CD2 . LEU H 1 200 ? 66.456 -80.727 32.749 1.00 124.28 ? 200 LEU H CD2 1 +ATOM 14793 N N . GLU H 1 201 ? 63.532 -78.895 35.843 1.00 195.51 ? 201 GLU H N 1 +ATOM 14794 C CA . GLU H 1 201 ? 63.062 -77.747 35.080 1.00 207.55 ? 201 GLU H CA 1 +ATOM 14795 C C . GLU H 1 201 ? 64.131 -76.664 35.057 1.00 207.67 ? 201 GLU H C 1 +ATOM 14796 O O . GLU H 1 201 ? 64.895 -76.511 36.011 1.00 177.64 ? 201 GLU H O 1 +ATOM 14797 C CB . GLU H 1 201 ? 61.777 -77.185 35.681 1.00 216.54 ? 201 GLU H CB 1 +ATOM 14798 C CG . GLU H 1 201 ? 61.002 -76.307 34.710 1.00 211.54 ? 201 GLU H CG 1 +ATOM 14799 C CD . GLU H 1 201 ? 59.720 -75.743 35.307 1.00 217.59 ? 201 GLU H CD 1 +ATOM 14800 O OE1 . GLU H 1 201 ? 58.913 -76.526 35.861 1.00 260.46 ? 201 GLU H OE1 1 +ATOM 14801 O OE2 . GLU H 1 201 ? 59.489 -74.526 35.182 1.00 185.23 ? 201 GLU H OE2 1 +ATOM 14802 N N . GLY H 1 202 ? 64.185 -75.914 33.959 1.00 224.62 ? 202 GLY H N 1 +ATOM 14803 C CA . GLY H 1 202 ? 65.074 -74.757 33.861 1.00 227.31 ? 202 GLY H CA 1 +ATOM 14804 C C . GLY H 1 202 ? 64.551 -73.728 32.879 1.00 218.67 ? 202 GLY H C 1 +ATOM 14805 O O . GLY H 1 202 ? 64.240 -74.059 31.735 1.00 241.83 ? 202 GLY H O 1 +ATOM 14806 N N . GLU H 1 203 ? 64.420 -72.484 33.331 1.00 199.70 ? 203 GLU H N 1 +ATOM 14807 C CA . GLU H 1 203 ? 63.830 -71.440 32.502 1.00 172.67 ? 203 GLU H CA 1 +ATOM 14808 C C . GLU H 1 203 ? 64.675 -70.172 32.442 1.00 142.75 ? 203 GLU H C 1 +ATOM 14809 O O . GLU H 1 203 ? 65.173 -69.685 33.457 1.00 108.21 ? 203 GLU H O 1 +ATOM 14810 C CB . GLU H 1 203 ? 62.424 -71.102 32.994 1.00 182.62 ? 203 GLU H CB 1 +ATOM 14811 C CG . GLU H 1 203 ? 61.425 -72.247 32.812 1.00 189.81 ? 203 GLU H CG 1 +ATOM 14812 C CD . GLU H 1 203 ? 59.992 -71.900 33.202 1.00 197.49 ? 203 GLU H CD 1 +ATOM 14813 O OE1 . GLU H 1 203 ? 59.773 -70.807 33.767 1.00 173.72 ? 203 GLU H OE1 1 +ATOM 14814 O OE2 . GLU H 1 203 ? 59.088 -72.728 32.946 1.00 198.28 ? 203 GLU H OE2 1 +ATOM 14815 N N . VAL H 1 204 ? 64.824 -69.657 31.228 1.00 130.51 ? 204 VAL H N 1 +ATOM 14816 C CA . VAL H 1 204 ? 65.488 -68.388 30.989 1.00 140.15 ? 204 VAL H CA 1 +ATOM 14817 C C . VAL H 1 204 ? 64.527 -67.479 30.239 1.00 164.03 ? 204 VAL H C 1 +ATOM 14818 O O . VAL H 1 204 ? 63.843 -67.906 29.300 1.00 198.35 ? 204 VAL H O 1 +ATOM 14819 C CB . VAL H 1 204 ? 66.791 -68.584 30.183 1.00 138.22 ? 204 VAL H CB 1 +ATOM 14820 C CG1 . VAL H 1 204 ? 67.290 -67.268 29.586 1.00 149.57 ? 204 VAL H CG1 1 +ATOM 14821 C CG2 . VAL H 1 204 ? 67.857 -69.212 31.073 1.00 124.90 ? 204 VAL H CG2 1 +ATOM 14822 N N . GLY H 1 205 ? 64.467 -66.222 30.667 1.00 183.39 ? 205 GLY H N 1 +ATOM 14823 C CA . GLY H 1 205 ? 63.645 -65.225 29.999 1.00 183.82 ? 205 GLY H CA 1 +ATOM 14824 C C . GLY H 1 205 ? 64.355 -63.889 29.837 1.00 175.71 ? 205 GLY H C 1 +ATOM 14825 O O . GLY H 1 205 ? 65.223 -63.532 30.638 1.00 138.03 ? 205 GLY H O 1 +ATOM 14826 N N . TYR H 1 206 ? 63.986 -63.151 28.792 1.00 167.41 ? 206 TYR H N 1 +ATOM 14827 C CA . TYR H 1 206 ? 64.486 -61.791 28.589 1.00 141.85 ? 206 TYR H CA 1 +ATOM 14828 C C . TYR H 1 206 ? 63.418 -60.941 27.916 1.00 160.96 ? 206 TYR H C 1 +ATOM 14829 O O . TYR H 1 206 ? 62.710 -61.420 27.039 1.00 190.10 ? 206 TYR H O 1 +ATOM 14830 C CB . TYR H 1 206 ? 65.737 -61.805 27.720 1.00 128.90 ? 206 TYR H CB 1 +ATOM 14831 C CG . TYR H 1 206 ? 66.268 -60.422 27.406 1.00 128.49 ? 206 TYR H CG 1 +ATOM 14832 C CD1 . TYR H 1 206 ? 66.958 -59.670 28.374 1.00 104.00 ? 206 TYR H CD1 1 +ATOM 14833 C CD2 . TYR H 1 206 ? 66.085 -59.868 26.138 1.00 134.87 ? 206 TYR H CD2 1 +ATOM 14834 C CE1 . TYR H 1 206 ? 67.487 -58.429 28.073 1.00 101.72 ? 206 TYR H CE1 1 +ATOM 14835 C CE2 . TYR H 1 206 ? 66.602 -58.625 25.831 1.00 140.57 ? 206 TYR H CE2 1 +ATOM 14836 C CZ . TYR H 1 206 ? 67.300 -57.914 26.798 1.00 138.03 ? 206 TYR H CZ 1 +ATOM 14837 O OH . TYR H 1 206 ? 67.748 -56.656 26.477 1.00 193.91 ? 206 TYR H OH 1 +ATOM 14838 N N . THR H 1 207 ? 63.311 -59.677 28.318 1.00 173.17 ? 207 THR H N 1 +ATOM 14839 C CA . THR H 1 207 ? 62.342 -58.758 27.714 1.00 151.16 ? 207 THR H CA 1 +ATOM 14840 C C . THR H 1 207 ? 62.954 -57.371 27.480 1.00 128.64 ? 207 THR H C 1 +ATOM 14841 O O . THR H 1 207 ? 63.685 -56.850 28.335 1.00 109.94 ? 207 THR H O 1 +ATOM 14842 C CB . THR H 1 207 ? 61.087 -58.600 28.599 1.00 149.48 ? 207 THR H CB 1 +ATOM 14843 O OG1 . THR H 1 207 ? 61.460 -58.047 29.866 1.00 141.55 ? 207 THR H OG1 1 +ATOM 14844 C CG2 . THR H 1 207 ? 60.412 -59.933 28.831 1.00 143.80 ? 207 THR H CG2 1 +ATOM 14845 N N . SER H 1 208 ? 62.672 -56.784 26.319 1.00 107.54 ? 208 SER H N 1 +ATOM 14846 C CA . SER H 1 208 ? 63.211 -55.460 26.001 1.00 118.16 ? 208 SER H CA 1 +ATOM 14847 C C . SER H 1 208 ? 62.154 -54.531 25.430 1.00 123.29 ? 208 SER H C 1 +ATOM 14848 O O . SER H 1 208 ? 61.500 -54.859 24.445 1.00 116.15 ? 208 SER H O 1 +ATOM 14849 C CB . SER H 1 208 ? 64.393 -55.551 25.030 1.00 120.23 ? 208 SER H CB 1 +ATOM 14850 O OG . SER H 1 208 ? 64.814 -54.259 24.597 1.00 111.75 ? 208 SER H OG 1 +ATOM 14851 N N . ASN H 1 209 ? 62.029 -53.362 26.056 1.00 147.28 ? 209 ASN H N 1 +ATOM 14852 C CA . ASN H 1 209 ? 61.187 -52.269 25.573 1.00 122.76 ? 209 ASN H CA 1 +ATOM 14853 C C . ASN H 1 209 ? 62.026 -51.083 25.165 1.00 109.41 ? 209 ASN H C 1 +ATOM 14854 O O . ASN H 1 209 ? 62.986 -50.724 25.861 1.00 159.08 ? 209 ASN H O 1 +ATOM 14855 C CB . ASN H 1 209 ? 60.242 -51.798 26.668 1.00 99.91 ? 209 ASN H CB 1 +ATOM 14856 C CG . ASN H 1 209 ? 59.188 -52.823 26.993 1.00 94.57 ? 209 ASN H CG 1 +ATOM 14857 O OD1 . ASN H 1 209 ? 58.171 -52.918 26.310 1.00 128.77 ? 209 ASN H OD1 1 +ATOM 14858 N ND2 . ASN H 1 209 ? 59.417 -53.584 28.033 1.00 74.65 ? 209 ASN H ND2 1 +ATOM 14859 N N . GLU H 1 210 ? 61.703 -50.510 24.018 1.00 83.14 ? 210 GLU H N 1 +ATOM 14860 C CA . GLU H 1 210 ? 62.307 -49.245 23.651 1.00 89.06 ? 210 GLU H CA 1 +ATOM 14861 C C . GLU H 1 210 ? 61.791 -48.207 24.619 1.00 99.94 ? 210 GLU H C 1 +ATOM 14862 O O . GLU H 1 210 ? 60.626 -48.240 25.026 1.00 117.06 ? 210 GLU H O 1 +ATOM 14863 C CB . GLU H 1 210 ? 61.938 -48.868 22.224 1.00 91.20 ? 210 GLU H CB 1 +ATOM 14864 C CG . GLU H 1 210 ? 63.069 -48.307 21.391 1.00 100.68 ? 210 GLU H CG 1 +ATOM 14865 C CD . GLU H 1 210 ? 62.759 -48.348 19.894 1.00 143.78 ? 210 GLU H CD 1 +ATOM 14866 O OE1 . GLU H 1 210 ? 61.971 -49.222 19.416 1.00 159.92 ? 210 GLU H OE1 1 +ATOM 14867 O OE2 . GLU H 1 210 ? 63.344 -47.517 19.169 1.00 198.04 ? 210 GLU H OE2 1 +ATOM 14868 N N . PRO H 1 211 ? 62.651 -47.265 25.001 1.00 123.92 ? 211 PRO H N 1 +ATOM 14869 C CA . PRO H 1 211 ? 62.148 -46.133 25.772 1.00 155.50 ? 211 PRO H CA 1 +ATOM 14870 C C . PRO H 1 211 ? 61.321 -45.157 24.918 1.00 157.60 ? 211 PRO H C 1 +ATOM 14871 O O . PRO H 1 211 ? 61.796 -44.686 23.882 1.00 111.96 ? 211 PRO H O 1 +ATOM 14872 C CB . PRO H 1 211 ? 63.429 -45.458 26.285 1.00 161.21 ? 211 PRO H CB 1 +ATOM 14873 C CG . PRO H 1 211 ? 64.504 -46.481 26.133 1.00 130.89 ? 211 PRO H CG 1 +ATOM 14874 C CD . PRO H 1 211 ? 64.114 -47.256 24.917 1.00 128.36 ? 211 PRO H CD 1 +ATOM 14875 N N . VAL H 1 212 ? 60.099 -44.866 25.369 1.00 134.42 ? 212 VAL H N 1 +ATOM 14876 C CA . VAL H 1 212 ? 59.203 -43.959 24.661 1.00 111.10 ? 212 VAL H CA 1 +ATOM 14877 C C . VAL H 1 212 ? 59.823 -42.580 24.684 1.00 105.50 ? 212 VAL H C 1 +ATOM 14878 O O . VAL H 1 212 ? 59.801 -41.833 23.703 1.00 109.01 ? 212 VAL H O 1 +ATOM 14879 C CB . VAL H 1 212 ? 57.822 -43.902 25.337 1.00 99.95 ? 212 VAL H CB 1 +ATOM 14880 C CG1 . VAL H 1 212 ? 56.875 -43.040 24.504 1.00 102.18 ? 212 VAL H CG1 1 +ATOM 14881 C CG2 . VAL H 1 212 ? 57.235 -45.306 25.520 1.00 119.86 ? 212 VAL H CG2 1 +ATOM 14882 N N . MET H 1 213 ? 60.367 -42.258 25.849 1.00 111.90 ? 213 MET H N 1 +ATOM 14883 C CA . MET H 1 213 ? 61.289 -41.129 26.075 1.00 121.15 ? 213 MET H CA 1 +ATOM 14884 C C . MET H 1 213 ? 62.267 -40.848 24.914 1.00 90.13 ? 213 MET H C 1 +ATOM 14885 O O . MET H 1 213 ? 62.354 -39.741 24.383 1.00 56.80 ? 213 MET H O 1 +ATOM 14886 C CB . MET H 1 213 ? 62.060 -41.522 27.334 1.00 156.91 ? 213 MET H CB 1 +ATOM 14887 C CG . MET H 1 213 ? 63.029 -40.532 27.908 1.00 212.84 ? 213 MET H CG 1 +ATOM 14888 S SD . MET H 1 213 ? 63.752 -41.352 29.365 1.00 228.28 ? 213 MET H SD 1 +ATOM 14889 C CE . MET H 1 213 ? 65.391 -41.541 28.695 1.00 252.37 ? 213 MET H CE 1 +ATOM 14890 N N . LEU H 1 214 ? 62.890 -41.912 24.452 1.00 96.46 ? 214 LEU H N 1 +ATOM 14891 C CA . LEU H 1 214 ? 64.015 -41.806 23.558 1.00 119.04 ? 214 LEU H CA 1 +ATOM 14892 C C . LEU H 1 214 ? 63.487 -41.689 22.148 1.00 101.51 ? 214 LEU H C 1 +ATOM 14893 O O . LEU H 1 214 ? 64.146 -41.137 21.267 1.00 109.04 ? 214 LEU H O 1 +ATOM 14894 C CB . LEU H 1 214 ? 64.935 -43.043 23.732 1.00 171.55 ? 214 LEU H CB 1 +ATOM 14895 C CG . LEU H 1 214 ? 66.457 -42.855 23.764 1.00 186.51 ? 214 LEU H CG 1 +ATOM 14896 C CD1 . LEU H 1 214 ? 66.897 -41.923 24.896 1.00 210.03 ? 214 LEU H CD1 1 +ATOM 14897 C CD2 . LEU H 1 214 ? 67.155 -44.206 23.894 1.00 159.66 ? 214 LEU H CD2 1 +ATOM 14898 N N . CYS H 1 215 ? 62.336 -42.311 21.911 1.00 105.50 ? 215 CYS H N 1 +ATOM 14899 C CA . CYS H 1 215 ? 61.710 -42.289 20.587 1.00 132.66 ? 215 CYS H CA 1 +ATOM 14900 C C . CYS H 1 215 ? 61.144 -40.903 20.315 1.00 153.38 ? 215 CYS H C 1 +ATOM 14901 O O . CYS H 1 215 ? 61.225 -40.373 19.185 1.00 163.79 ? 215 CYS H O 1 +ATOM 14902 C CB . CYS H 1 215 ? 60.579 -43.311 20.511 1.00 119.46 ? 215 CYS H CB 1 +ATOM 14903 S SG . CYS H 1 215 ? 61.121 -45.019 20.631 1.00 101.18 ? 215 CYS H SG 1 +ATOM 14904 N N . LEU H 1 216 ? 60.543 -40.330 21.354 1.00 137.10 ? 216 LEU H N 1 +ATOM 14905 C CA . LEU H 1 216 ? 60.063 -38.965 21.278 1.00 124.49 ? 216 LEU H CA 1 +ATOM 14906 C C . LEU H 1 216 ? 61.221 -38.045 20.911 1.00 125.87 ? 216 LEU H C 1 +ATOM 14907 O O . LEU H 1 216 ? 61.113 -37.235 19.977 1.00 122.29 ? 216 LEU H O 1 +ATOM 14908 C CB . LEU H 1 216 ? 59.445 -38.537 22.600 1.00 111.90 ? 216 LEU H CB 1 +ATOM 14909 C CG . LEU H 1 216 ? 58.954 -37.085 22.637 1.00 96.43 ? 216 LEU H CG 1 +ATOM 14910 C CD1 . LEU H 1 216 ? 57.926 -36.785 21.566 1.00 89.24 ? 216 LEU H CD1 1 +ATOM 14911 C CD2 . LEU H 1 216 ? 58.370 -36.787 24.013 1.00 114.40 ? 216 LEU H CD2 1 +ATOM 14912 N N . MET H 1 217 ? 62.353 -38.232 21.593 1.00 98.44 ? 217 MET H N 1 +ATOM 14913 C CA . MET H 1 217 ? 63.498 -37.360 21.383 1.00 117.13 ? 217 MET H CA 1 +ATOM 14914 C C . MET H 1 217 ? 64.011 -37.489 19.954 1.00 113.52 ? 217 MET H C 1 +ATOM 14915 O O . MET H 1 217 ? 64.218 -36.487 19.262 1.00 91.11 ? 217 MET H O 1 +ATOM 14916 C CB . MET H 1 217 ? 64.608 -37.671 22.385 1.00 135.62 ? 217 MET H CB 1 +ATOM 14917 C CG . MET H 1 217 ? 65.258 -36.422 22.974 1.00 135.85 ? 217 MET H CG 1 +ATOM 14918 S SD . MET H 1 217 ? 66.240 -35.514 21.765 1.00 139.52 ? 217 MET H SD 1 +ATOM 14919 C CE . MET H 1 217 ? 66.620 -33.998 22.643 1.00 164.96 ? 217 MET H CE 1 +ATOM 14920 N N . SER H 1 218 ? 64.146 -38.731 19.499 1.00 115.69 ? 218 SER H N 1 +ATOM 14921 C CA . SER H 1 218 ? 64.581 -39.022 18.135 1.00 135.90 ? 218 SER H CA 1 +ATOM 14922 C C . SER H 1 218 ? 63.688 -38.325 17.090 1.00 149.49 ? 218 SER H C 1 +ATOM 14923 O O . SER H 1 218 ? 64.183 -37.656 16.173 1.00 138.28 ? 218 SER H O 1 +ATOM 14924 C CB . SER H 1 218 ? 64.577 -40.540 17.896 1.00 122.90 ? 218 SER H CB 1 +ATOM 14925 O OG . SER H 1 218 ? 65.210 -40.867 16.671 1.00 138.97 ? 218 SER H OG 1 +ATOM 14926 N N . ALA H 1 219 ? 62.379 -38.505 17.227 1.00 119.36 ? 219 ALA H N 1 +ATOM 14927 C CA . ALA H 1 219 ? 61.445 -37.993 16.252 1.00 107.87 ? 219 ALA H CA 1 +ATOM 14928 C C . ALA H 1 219 ? 61.478 -36.452 16.207 1.00 124.53 ? 219 ALA H C 1 +ATOM 14929 O O . ALA H 1 219 ? 61.297 -35.828 15.146 1.00 110.34 ? 219 ALA H O 1 +ATOM 14930 C CB . ALA H 1 219 ? 60.055 -38.503 16.579 1.00 112.34 ? 219 ALA H CB 1 +ATOM 14931 N N . ILE H 1 220 ? 61.682 -35.825 17.361 1.00 123.29 ? 220 ILE H N 1 +ATOM 14932 C CA . ILE H 1 220 ? 61.745 -34.361 17.415 1.00 118.46 ? 220 ILE H CA 1 +ATOM 14933 C C . ILE H 1 220 ? 62.985 -33.849 16.667 1.00 128.81 ? 220 ILE H C 1 +ATOM 14934 O O . ILE H 1 220 ? 62.923 -32.853 15.947 1.00 74.81 ? 220 ILE H O 1 +ATOM 14935 C CB . ILE H 1 220 ? 61.737 -33.849 18.874 1.00 120.82 ? 220 ILE H CB 1 +ATOM 14936 C CG1 . ILE H 1 220 ? 60.356 -34.107 19.503 1.00 99.69 ? 220 ILE H CG1 1 +ATOM 14937 C CG2 . ILE H 1 220 ? 62.116 -32.356 18.930 1.00 102.70 ? 220 ILE H CG2 1 +ATOM 14938 C CD1 . ILE H 1 220 ? 60.332 -34.019 21.011 1.00 98.94 ? 220 ILE H CD1 1 +ATOM 14939 N N . GLU H 1 221 ? 64.111 -34.546 16.840 1.00 134.57 ? 221 GLU H N 1 +ATOM 14940 C CA . GLU H 1 221 ? 65.347 -34.204 16.126 1.00 108.22 ? 221 GLU H CA 1 +ATOM 14941 C C . GLU H 1 221 ? 65.107 -34.248 14.621 1.00 118.27 ? 221 GLU H C 1 +ATOM 14942 O O . GLU H 1 221 ? 65.404 -33.289 13.895 1.00 81.31 ? 221 GLU H O 1 +ATOM 14943 C CB . GLU H 1 221 ? 66.466 -35.171 16.519 1.00 85.54 ? 221 GLU H CB 1 +ATOM 14944 C CG . GLU H 1 221 ? 67.032 -34.920 17.909 1.00 83.46 ? 221 GLU H CG 1 +ATOM 14945 C CD . GLU H 1 221 ? 67.811 -36.098 18.490 1.00 81.55 ? 221 GLU H CD 1 +ATOM 14946 O OE1 . GLU H 1 221 ? 67.470 -37.284 18.224 1.00 53.27 ? 221 GLU H OE1 1 +ATOM 14947 O OE2 . GLU H 1 221 ? 68.823 -35.815 19.179 1.00 83.79 ? 221 GLU H OE2 1 +ATOM 14948 N N . THR H 1 222 ? 64.543 -35.371 14.175 1.00 135.30 ? 222 THR H N 1 +ATOM 14949 C CA . THR H 1 222 ? 64.191 -35.591 12.772 1.00 126.86 ? 222 THR H CA 1 +ATOM 14950 C C . THR H 1 222 ? 63.360 -34.432 12.245 1.00 111.94 ? 222 THR H C 1 +ATOM 14951 O O . THR H 1 222 ? 63.619 -33.908 11.157 1.00 88.89 ? 222 THR H O 1 +ATOM 14952 C CB . THR H 1 222 ? 63.387 -36.907 12.622 1.00 113.70 ? 222 THR H CB 1 +ATOM 14953 O OG1 . THR H 1 222 ? 64.249 -38.040 12.828 1.00 106.32 ? 222 THR H OG1 1 +ATOM 14954 C CG2 . THR H 1 222 ? 62.703 -36.982 11.242 1.00 111.26 ? 222 THR H CG2 1 +ATOM 14955 N N . GLY H 1 223 ? 62.337 -34.066 13.015 1.00 103.66 ? 223 GLY H N 1 +ATOM 14956 C CA . GLY H 1 223 ? 61.483 -32.941 12.667 1.00 128.48 ? 223 GLY H CA 1 +ATOM 14957 C C . GLY H 1 223 ? 62.280 -31.656 12.483 1.00 122.21 ? 223 GLY H C 1 +ATOM 14958 O O . GLY H 1 223 ? 61.976 -30.852 11.581 1.00 88.33 ? 223 GLY H O 1 +ATOM 14959 N N . VAL H 1 224 ? 63.264 -31.435 13.355 1.00 106.12 ? 224 VAL H N 1 +ATOM 14960 C CA . VAL H 1 224 ? 64.043 -30.205 13.300 1.00 128.08 ? 224 VAL H CA 1 +ATOM 14961 C C . VAL H 1 224 ? 64.830 -30.176 12.001 1.00 141.00 ? 224 VAL H C 1 +ATOM 14962 O O . VAL H 1 224 ? 64.907 -29.139 11.334 1.00 142.20 ? 224 VAL H O 1 +ATOM 14963 C CB . VAL H 1 224 ? 65.010 -30.083 14.481 1.00 131.69 ? 224 VAL H CB 1 +ATOM 14964 C CG1 . VAL H 1 224 ? 65.945 -28.899 14.273 1.00 119.27 ? 224 VAL H CG1 1 +ATOM 14965 C CG2 . VAL H 1 224 ? 64.235 -29.936 15.783 1.00 148.36 ? 224 VAL H CG2 1 +ATOM 14966 N N . ILE H 1 225 ? 65.365 -31.329 11.611 1.00 137.49 ? 225 ILE H N 1 +ATOM 14967 C CA . ILE H 1 225 ? 66.102 -31.417 10.353 1.00 125.92 ? 225 ILE H CA 1 +ATOM 14968 C C . ILE H 1 225 ? 65.192 -31.065 9.182 1.00 121.03 ? 225 ILE H C 1 +ATOM 14969 O O . ILE H 1 225 ? 65.547 -30.208 8.372 1.00 95.92 ? 225 ILE H O 1 +ATOM 14970 C CB . ILE H 1 225 ? 66.730 -32.810 10.134 1.00 114.55 ? 225 ILE H CB 1 +ATOM 14971 C CG1 . ILE H 1 225 ? 67.844 -33.045 11.156 1.00 123.50 ? 225 ILE H CG1 1 +ATOM 14972 C CG2 . ILE H 1 225 ? 67.313 -32.920 8.727 1.00 93.35 ? 225 ILE H CG2 1 +ATOM 14973 C CD1 . ILE H 1 225 ? 68.230 -34.499 11.319 1.00 117.41 ? 225 ILE H CD1 1 +ATOM 14974 N N . PHE H 1 226 ? 64.028 -31.721 9.104 1.00 111.06 ? 226 PHE H N 1 +ATOM 14975 C CA . PHE H 1 226 ? 63.067 -31.471 8.018 1.00 111.53 ? 226 PHE H CA 1 +ATOM 14976 C C . PHE H 1 226 ? 62.667 -29.997 7.961 1.00 115.59 ? 226 PHE H C 1 +ATOM 14977 O O . PHE H 1 226 ? 62.421 -29.450 6.888 1.00 118.79 ? 226 PHE H O 1 +ATOM 14978 C CB . PHE H 1 226 ? 61.807 -32.342 8.166 1.00 103.75 ? 226 PHE H CB 1 +ATOM 14979 C CG . PHE H 1 226 ? 61.961 -33.762 7.672 1.00 96.97 ? 226 PHE H CG 1 +ATOM 14980 C CD1 . PHE H 1 226 ? 62.262 -34.021 6.339 1.00 107.79 ? 226 PHE H CD1 1 +ATOM 14981 C CD2 . PHE H 1 226 ? 61.711 -34.844 8.516 1.00 93.31 ? 226 PHE H CD2 1 +ATOM 14982 C CE1 . PHE H 1 226 ? 62.403 -35.329 5.880 1.00 109.60 ? 226 PHE H CE1 1 +ATOM 14983 C CE2 . PHE H 1 226 ? 61.820 -36.148 8.059 1.00 94.67 ? 226 PHE H CE2 1 +ATOM 14984 C CZ . PHE H 1 226 ? 62.181 -36.392 6.742 1.00 112.28 ? 226 PHE H CZ 1 +ATOM 14985 N N . LEU H 1 227 ? 62.601 -29.360 9.121 1.00 117.21 ? 227 LEU H N 1 +ATOM 14986 C CA . LEU H 1 227 ? 62.293 -27.936 9.188 1.00 126.34 ? 227 LEU H CA 1 +ATOM 14987 C C . LEU H 1 227 ? 63.404 -27.082 8.596 1.00 118.38 ? 227 LEU H C 1 +ATOM 14988 O O . LEU H 1 227 ? 63.135 -26.160 7.840 1.00 85.25 ? 227 LEU H O 1 +ATOM 14989 C CB . LEU H 1 227 ? 62.051 -27.545 10.642 1.00 139.25 ? 227 LEU H CB 1 +ATOM 14990 C CG . LEU H 1 227 ? 60.685 -27.934 11.233 1.00 128.64 ? 227 LEU H CG 1 +ATOM 14991 C CD1 . LEU H 1 227 ? 60.576 -27.799 12.736 1.00 121.78 ? 227 LEU H CD1 1 +ATOM 14992 C CD2 . LEU H 1 227 ? 59.562 -27.155 10.582 1.00 129.28 ? 227 LEU H CD2 1 +ATOM 14993 N N . ILE H 1 228 ? 64.651 -27.405 8.932 1.00 139.74 ? 228 ILE H N 1 +ATOM 14994 C CA . ILE H 1 228 ? 65.794 -26.653 8.426 1.00 134.72 ? 228 ILE H CA 1 +ATOM 14995 C C . ILE H 1 228 ? 65.879 -26.820 6.917 1.00 138.39 ? 228 ILE H C 1 +ATOM 14996 O O . ILE H 1 228 ? 66.043 -25.841 6.184 1.00 131.24 ? 228 ILE H O 1 +ATOM 14997 C CB . ILE H 1 228 ? 67.132 -27.104 9.053 1.00 133.36 ? 228 ILE H CB 1 +ATOM 14998 C CG1 . ILE H 1 228 ? 67.147 -26.831 10.557 1.00 158.80 ? 228 ILE H CG1 1 +ATOM 14999 C CG2 . ILE H 1 228 ? 68.290 -26.353 8.418 1.00 110.90 ? 228 ILE H CG2 1 +ATOM 15000 C CD1 . ILE H 1 228 ? 68.240 -27.556 11.316 1.00 153.22 ? 228 ILE H CD1 1 +ATOM 15001 N N . ASN H 1 229 ? 65.771 -28.065 6.456 1.00 135.07 ? 229 ASN H N 1 +ATOM 15002 C CA . ASN H 1 229 ? 65.865 -28.370 5.029 1.00 128.21 ? 229 ASN H CA 1 +ATOM 15003 C C . ASN H 1 229 ? 64.758 -27.664 4.251 1.00 122.96 ? 229 ASN H C 1 +ATOM 15004 O O . ASN H 1 229 ? 65.012 -27.031 3.219 1.00 87.73 ? 229 ASN H O 1 +ATOM 15005 C CB . ASN H 1 229 ? 65.788 -29.885 4.816 1.00 117.95 ? 229 ASN H CB 1 +ATOM 15006 C CG . ASN H 1 229 ? 66.284 -30.314 3.450 1.00 160.25 ? 229 ASN H CG 1 +ATOM 15007 O OD1 . ASN H 1 229 ? 67.027 -29.590 2.780 1.00 179.72 ? 229 ASN H OD1 1 +ATOM 15008 N ND2 . ASN H 1 229 ? 65.827 -31.476 3.003 1.00 181.40 ? 229 ASN H ND2 1 +ATOM 15009 N N . ASP H 1 230 ? 63.551 -27.706 4.805 1.00 126.13 ? 230 ASP H N 1 +ATOM 15010 C CA . ASP H 1 230 ? 62.415 -27.027 4.213 1.00 138.83 ? 230 ASP H CA 1 +ATOM 15011 C C . ASP H 1 230 ? 62.667 -25.521 4.130 1.00 161.48 ? 230 ASP H C 1 +ATOM 15012 O O . ASP H 1 230 ? 62.337 -24.867 3.137 1.00 178.67 ? 230 ASP H O 1 +ATOM 15013 C CB . ASP H 1 230 ? 61.156 -27.309 5.028 1.00 136.89 ? 230 ASP H CB 1 +ATOM 15014 C CG . ASP H 1 230 ? 59.909 -26.753 4.375 1.00 173.24 ? 230 ASP H CG 1 +ATOM 15015 O OD1 . ASP H 1 230 ? 59.479 -27.320 3.352 1.00 216.25 ? 230 ASP H OD1 1 +ATOM 15016 O OD2 . ASP H 1 230 ? 59.350 -25.745 4.866 1.00 228.13 ? 230 ASP H OD2 1 +ATOM 15017 N N . GLY H 1 231 ? 63.234 -24.961 5.192 1.00 164.23 ? 231 GLY H N 1 +ATOM 15018 C CA . GLY H 1 231 ? 63.519 -23.528 5.231 1.00 175.95 ? 231 GLY H CA 1 +ATOM 15019 C C . GLY H 1 231 ? 64.591 -23.123 4.229 1.00 167.35 ? 231 GLY H C 1 +ATOM 15020 O O . GLY H 1 231 ? 64.549 -22.020 3.662 1.00 104.00 ? 231 GLY H O 1 +ATOM 15021 N N . ILE H 1 232 ? 65.563 -24.011 4.029 1.00 167.02 ? 232 ILE H N 1 +ATOM 15022 C CA . ILE H 1 232 ? 66.601 -23.793 3.031 1.00 157.60 ? 232 ILE H CA 1 +ATOM 15023 C C . ILE H 1 232 ? 65.952 -23.687 1.662 1.00 147.34 ? 232 ILE H C 1 +ATOM 15024 O O . ILE H 1 232 ? 66.246 -22.746 0.910 1.00 145.22 ? 232 ILE H O 1 +ATOM 15025 C CB . ILE H 1 232 ? 67.654 -24.923 3.048 1.00 154.60 ? 232 ILE H CB 1 +ATOM 15026 C CG1 . ILE H 1 232 ? 68.543 -24.780 4.287 1.00 159.12 ? 232 ILE H CG1 1 +ATOM 15027 C CG2 . ILE H 1 232 ? 68.505 -24.909 1.782 1.00 171.42 ? 232 ILE H CG2 1 +ATOM 15028 C CD1 . ILE H 1 232 ? 69.318 -26.034 4.639 1.00 175.46 ? 232 ILE H CD1 1 +ATOM 15029 N N . ASP H 1 233 ? 65.097 -24.662 1.342 1.00 112.50 ? 233 ASP H N 1 +ATOM 15030 C CA . ASP H 1 233 ? 64.406 -24.691 0.060 1.00 117.79 ? 233 ASP H CA 1 +ATOM 15031 C C . ASP H 1 233 ? 63.600 -23.416 -0.149 1.00 126.35 ? 233 ASP H C 1 +ATOM 15032 O O . ASP H 1 233 ? 63.680 -22.778 -1.210 1.00 174.06 ? 233 ASP H O 1 +ATOM 15033 C CB . ASP H 1 233 ? 63.467 -25.903 -0.022 1.00 120.19 ? 233 ASP H CB 1 +ATOM 15034 C CG . ASP H 1 233 ? 64.209 -27.246 -0.010 1.00 113.02 ? 233 ASP H CG 1 +ATOM 15035 O OD1 . ASP H 1 233 ? 65.438 -27.255 0.178 1.00 84.86 ? 233 ASP H OD1 1 +ATOM 15036 O OD2 . ASP H 1 233 ? 63.560 -28.279 -0.313 1.00 118.06 ? 233 ASP H OD2 1 +ATOM 15037 N N . ARG H 1 234 ? 62.838 -23.034 0.865 1.00 128.57 ? 234 ARG H N 1 +ATOM 15038 C CA . ARG H 1 234 ? 61.908 -21.909 0.745 1.00 156.41 ? 234 ARG H CA 1 +ATOM 15039 C C . ARG H 1 234 ? 62.542 -20.520 0.942 1.00 146.62 ? 234 ARG H C 1 +ATOM 15040 O O . ARG H 1 234 ? 61.855 -19.495 0.824 1.00 106.97 ? 234 ARG H O 1 +ATOM 15041 C CB . ARG H 1 234 ? 60.757 -22.088 1.728 1.00 167.94 ? 234 ARG H CB 1 +ATOM 15042 C CG . ARG H 1 234 ? 59.814 -23.183 1.300 1.00 169.45 ? 234 ARG H CG 1 +ATOM 15043 C CD . ARG H 1 234 ? 59.004 -23.723 2.456 1.00 168.81 ? 234 ARG H CD 1 +ATOM 15044 N NE . ARG H 1 234 ? 58.174 -24.814 1.971 1.00 194.50 ? 234 ARG H NE 1 +ATOM 15045 C CZ . ARG H 1 234 ? 56.848 -24.832 2.027 1.00 181.44 ? 234 ARG H CZ 1 +ATOM 15046 N NH1 . ARG H 1 234 ? 56.187 -23.853 2.643 1.00 124.97 ? 234 ARG H NH1 1 +ATOM 15047 N NH2 . ARG H 1 234 ? 56.182 -25.864 1.499 1.00 204.57 ? 234 ARG H NH2 1 +ATOM 15048 N N . GLY H 1 235 ? 63.843 -20.487 1.219 1.00 119.02 ? 235 GLY H N 1 +ATOM 15049 C CA . GLY H 1 235 ? 64.563 -19.228 1.305 1.00 118.06 ? 235 GLY H CA 1 +ATOM 15050 C C . GLY H 1 235 ? 64.296 -18.498 2.604 1.00 114.34 ? 235 GLY H C 1 +ATOM 15051 O O . GLY H 1 235 ? 64.312 -17.265 2.639 1.00 95.22 ? 235 GLY H O 1 +ATOM 15052 N N . LEU H 1 236 ? 64.084 -19.250 3.686 1.00 120.55 ? 236 LEU H N 1 +ATOM 15053 C CA . LEU H 1 236 ? 64.068 -18.641 5.035 1.00 118.01 ? 236 LEU H CA 1 +ATOM 15054 C C . LEU H 1 236 ? 65.497 -18.315 5.448 1.00 128.76 ? 236 LEU H C 1 +ATOM 15055 O O . LEU H 1 236 ? 65.789 -17.204 5.885 1.00 112.01 ? 236 LEU H O 1 +ATOM 15056 C CB . LEU H 1 236 ? 63.438 -19.570 6.084 1.00 102.91 ? 236 LEU H CB 1 +ATOM 15057 C CG . LEU H 1 236 ? 61.919 -19.577 6.210 1.00 95.00 ? 236 LEU H CG 1 +ATOM 15058 C CD1 . LEU H 1 236 ? 61.286 -20.406 5.090 1.00 117.40 ? 236 LEU H CD1 1 +ATOM 15059 C CD2 . LEU H 1 236 ? 61.497 -20.128 7.560 1.00 81.06 ? 236 LEU H CD2 1 +ATOM 15060 N N . TRP H 1 237 ? 66.389 -19.288 5.272 1.00 129.96 ? 237 TRP H N 1 +ATOM 15061 C CA . TRP H 1 237 ? 67.787 -19.132 5.655 1.00 146.31 ? 237 TRP H CA 1 +ATOM 15062 C C . TRP H 1 237 ? 68.711 -19.767 4.611 1.00 175.20 ? 237 TRP H C 1 +ATOM 15063 O O . TRP H 1 237 ? 68.249 -20.524 3.751 1.00 180.74 ? 237 TRP H O 1 +ATOM 15064 C CB . TRP H 1 237 ? 68.023 -19.747 7.031 1.00 135.17 ? 237 TRP H CB 1 +ATOM 15065 C CG . TRP H 1 237 ? 67.168 -20.931 7.287 1.00 124.98 ? 237 TRP H CG 1 +ATOM 15066 C CD1 . TRP H 1 237 ? 67.261 -22.141 6.682 1.00 155.66 ? 237 TRP H CD1 1 +ATOM 15067 C CD2 . TRP H 1 237 ? 66.090 -21.033 8.225 1.00 121.49 ? 237 TRP H CD2 1 +ATOM 15068 N NE1 . TRP H 1 237 ? 66.317 -23.000 7.190 1.00 172.58 ? 237 TRP H NE1 1 +ATOM 15069 C CE2 . TRP H 1 237 ? 65.604 -22.354 8.161 1.00 138.07 ? 237 TRP H CE2 1 +ATOM 15070 C CE3 . TRP H 1 237 ? 65.515 -20.152 9.134 1.00 142.62 ? 237 TRP H CE3 1 +ATOM 15071 C CZ2 . TRP H 1 237 ? 64.552 -22.810 8.955 1.00 140.84 ? 237 TRP H CZ2 1 +ATOM 15072 C CZ3 . TRP H 1 237 ? 64.461 -20.606 9.919 1.00 170.29 ? 237 TRP H CZ3 1 +ATOM 15073 C CH2 . TRP H 1 237 ? 63.984 -21.919 9.811 1.00 160.33 ? 237 TRP H CH2 1 +ATOM 15074 N N . ASP H 1 238 ? 70.002 -19.426 4.673 1.00 183.21 ? 238 ASP H N 1 +ATOM 15075 C CA . ASP H 1 238 ? 70.958 -19.809 3.630 1.00 159.70 ? 238 ASP H CA 1 +ATOM 15076 C C . ASP H 1 238 ? 72.207 -20.475 4.185 1.00 168.08 ? 238 ASP H C 1 +ATOM 15077 O O . ASP H 1 238 ? 72.675 -20.144 5.285 1.00 180.97 ? 238 ASP H O 1 +ATOM 15078 C CB . ASP H 1 238 ? 71.368 -18.599 2.791 1.00 113.99 ? 238 ASP H CB 1 +ATOM 15079 C CG . ASP H 1 238 ? 70.181 -17.892 2.164 1.00 124.26 ? 238 ASP H CG 1 +ATOM 15080 O OD1 . ASP H 1 238 ? 69.514 -17.126 2.868 1.00 102.52 ? 238 ASP H OD1 1 +ATOM 15081 O OD2 . ASP H 1 238 ? 69.886 -18.116 0.970 1.00 165.71 ? 238 ASP H OD2 1 +ATOM 15082 N N . LEU H 1 239 ? 72.750 -21.409 3.403 1.00 147.07 ? 239 LEU H N 1 +ATOM 15083 C CA . LEU H 1 239 ? 73.942 -22.142 3.797 1.00 169.36 ? 239 LEU H CA 1 +ATOM 15084 C C . LEU H 1 239 ? 75.177 -21.259 3.647 1.00 189.16 ? 239 LEU H C 1 +ATOM 15085 O O . LEU H 1 239 ? 75.269 -20.455 2.716 1.00 172.58 ? 239 LEU H O 1 +ATOM 15086 C CB . LEU H 1 239 ? 74.102 -23.416 2.950 1.00 166.54 ? 239 LEU H CB 1 +ATOM 15087 C CG . LEU H 1 239 ? 73.237 -24.642 3.247 1.00 147.27 ? 239 LEU H CG 1 +ATOM 15088 C CD1 . LEU H 1 239 ? 73.634 -25.814 2.364 1.00 157.11 ? 239 LEU H CD1 1 +ATOM 15089 C CD2 . LEU H 1 239 ? 73.349 -25.036 4.703 1.00 141.85 ? 239 LEU H CD2 1 +ATOM 15090 N N . GLN H 1 240 ? 76.131 -21.438 4.559 1.00 185.39 ? 240 GLN H N 1 +ATOM 15091 C CA . GLN H 1 240 ? 77.463 -20.856 4.408 1.00 168.26 ? 240 GLN H CA 1 +ATOM 15092 C C . GLN H 1 240 ? 78.074 -21.223 3.057 1.00 176.26 ? 240 GLN H C 1 +ATOM 15093 O O . GLN H 1 240 ? 78.407 -20.352 2.245 1.00 142.75 ? 240 GLN H O 1 +ATOM 15094 C CB . GLN H 1 240 ? 78.386 -21.333 5.541 1.00 153.88 ? 240 GLN H CB 1 +ATOM 15095 C CG . GLN H 1 240 ? 79.725 -20.609 5.585 1.00 145.62 ? 240 GLN H CG 1 +ATOM 15096 C CD . GLN H 1 240 ? 79.566 -19.130 5.906 1.00 162.52 ? 240 GLN H CD 1 +ATOM 15097 O OE1 . GLN H 1 240 ? 79.394 -18.750 7.070 1.00 180.73 ? 240 GLN H OE1 1 +ATOM 15098 N NE2 . GLN H 1 240 ? 79.573 -18.289 4.871 1.00 155.98 ? 240 GLN H NE2 1 +ATOM 15099 N N . ASN H 1 241 ? 78.175 -22.526 2.818 1.00 197.67 ? 241 ASN H N 1 +ATOM 15100 C CA . ASN H 1 241 ? 78.674 -23.051 1.563 1.00 205.28 ? 241 ASN H CA 1 +ATOM 15101 C C . ASN H 1 241 ? 77.547 -23.567 0.688 1.00 197.59 ? 241 ASN H C 1 +ATOM 15102 O O . ASN H 1 241 ? 76.973 -24.631 0.966 1.00 190.08 ? 241 ASN H O 1 +ATOM 15103 C CB . ASN H 1 241 ? 79.651 -24.181 1.839 1.00 220.32 ? 241 ASN H CB 1 +ATOM 15104 C CG . ASN H 1 241 ? 81.081 -23.721 1.739 1.00 270.87 ? 241 ASN H CG 1 +ATOM 15105 O OD1 . ASN H 1 241 ? 81.765 -24.027 0.758 1.00 380.62 ? 241 ASN H OD1 1 +ATOM 15106 N ND2 . ASN H 1 241 ? 81.563 -23.021 2.767 1.00 331.15 ? 241 ASN H ND2 1 +ATOM 15107 N N . LYS H 1 242 ? 77.300 -22.867 -0.420 1.00 156.48 ? 242 LYS H N 1 +ATOM 15108 C CA . LYS H 1 242 ? 76.266 -23.287 -1.365 1.00 128.97 ? 242 LYS H CA 1 +ATOM 15109 C C . LYS H 1 242 ? 76.627 -24.635 -1.993 1.00 145.59 ? 242 LYS H C 1 +ATOM 15110 O O . LYS H 1 242 ? 75.751 -25.413 -2.385 1.00 101.48 ? 242 LYS H O 1 +ATOM 15111 C CB . LYS H 1 242 ? 76.058 -22.219 -2.437 1.00 112.08 ? 242 LYS H CB 1 +ATOM 15112 C CG . LYS H 1 242 ? 75.913 -20.816 -1.878 1.00 113.82 ? 242 LYS H CG 1 +ATOM 15113 C CD . LYS H 1 242 ? 74.639 -20.144 -2.360 1.00 130.81 ? 242 LYS H CD 1 +ATOM 15114 C CE . LYS H 1 242 ? 73.901 -19.478 -1.204 1.00 157.99 ? 242 LYS H CE 1 +ATOM 15115 N NZ . LYS H 1 242 ? 72.733 -18.669 -1.654 1.00 149.81 ? 242 LYS H NZ 1 +ATOM 15116 N N . ALA H 1 243 ? 77.936 -24.898 -2.055 1.00 206.77 ? 243 ALA H N 1 +ATOM 15117 C CA . ALA H 1 243 ? 78.487 -26.181 -2.496 1.00 211.81 ? 243 ALA H CA 1 +ATOM 15118 C C . ALA H 1 243 ? 78.039 -27.329 -1.602 1.00 181.90 ? 243 ALA H C 1 +ATOM 15119 O O . ALA H 1 243 ? 78.132 -28.495 -2.004 1.00 202.94 ? 243 ALA H O 1 +ATOM 15120 C CB . ALA H 1 243 ? 80.013 -26.115 -2.525 1.00 235.94 ? 243 ALA H CB 1 +ATOM 15121 N N . GLU H 1 244 ? 77.596 -27.014 -0.384 1.00 140.80 ? 244 GLU H N 1 +ATOM 15122 C CA . GLU H 1 244 ? 77.209 -28.060 0.553 1.00 155.78 ? 244 GLU H CA 1 +ATOM 15123 C C . GLU H 1 244 ? 75.724 -28.391 0.462 1.00 158.57 ? 244 GLU H C 1 +ATOM 15124 O O . GLU H 1 244 ? 75.213 -29.075 1.334 1.00 123.89 ? 244 GLU H O 1 +ATOM 15125 C CB . GLU H 1 244 ? 77.589 -27.677 1.987 1.00 163.90 ? 244 GLU H CB 1 +ATOM 15126 C CG . GLU H 1 244 ? 79.081 -27.764 2.279 1.00 162.38 ? 244 GLU H CG 1 +ATOM 15127 C CD . GLU H 1 244 ? 79.399 -27.641 3.763 1.00 158.07 ? 244 GLU H CD 1 +ATOM 15128 O OE1 . GLU H 1 244 ? 79.364 -26.502 4.292 1.00 134.75 ? 244 GLU H OE1 1 +ATOM 15129 O OE2 . GLU H 1 244 ? 79.694 -28.683 4.394 1.00 115.78 ? 244 GLU H OE2 1 +ATOM 15130 N N . ARG H 1 245 ? 75.039 -27.872 -0.564 1.00 166.73 ? 245 ARG H N 1 +ATOM 15131 C CA . ARG H 1 245 ? 73.629 -28.209 -0.825 1.00 153.09 ? 245 ARG H CA 1 +ATOM 15132 C C . ARG H 1 245 ? 73.420 -29.720 -0.919 1.00 132.07 ? 245 ARG H C 1 +ATOM 15133 O O . ARG H 1 245 ? 72.405 -30.250 -0.475 1.00 134.94 ? 245 ARG H O 1 +ATOM 15134 C CB . ARG H 1 245 ? 73.080 -27.436 -2.087 1.00 149.94 ? 245 ARG H CB 1 +ATOM 15135 C CG . ARG H 1 245 ? 72.479 -26.156 -1.592 1.00 153.03 ? 245 ARG H CG 1 +ATOM 15136 C CD . ARG H 1 245 ? 71.749 -25.609 -2.848 1.00 180.42 ? 245 ARG H CD 1 +ATOM 15137 N NE . ARG H 1 245 ? 70.800 -26.592 -3.350 1.00 199.67 ? 245 ARG H NE 1 +ATOM 15138 C CZ . ARG H 1 245 ? 69.609 -26.903 -2.847 1.00 191.46 ? 245 ARG H CZ 1 +ATOM 15139 N NH1 . ARG H 1 245 ? 69.094 -26.281 -1.800 1.00 178.58 ? 245 ARG H NH1 1 +ATOM 15140 N NH2 . ARG H 1 245 ? 68.883 -27.853 -3.442 1.00 189.76 ? 245 ARG H NH2 1 +ATOM 15141 N N . GLN H 1 246 ? 74.374 -30.410 -1.538 1.00 126.96 ? 246 GLN H N 1 +ATOM 15142 C CA . GLN H 1 246 ? 74.210 -31.838 -1.828 1.00 130.15 ? 246 GLN H CA 1 +ATOM 15143 C C . GLN H 1 246 ? 74.827 -32.683 -0.723 1.00 113.67 ? 246 GLN H C 1 +ATOM 15144 O O . GLN H 1 246 ? 75.171 -33.846 -0.940 1.00 109.42 ? 246 GLN H O 1 +ATOM 15145 C CB . GLN H 1 246 ? 74.803 -32.206 -3.204 1.00 139.42 ? 246 GLN H CB 1 +ATOM 15146 C CG . GLN H 1 246 ? 74.006 -31.700 -4.407 1.00 156.78 ? 246 GLN H CG 1 +ATOM 15147 C CD . GLN H 1 246 ? 74.196 -30.217 -4.684 1.00 167.33 ? 246 GLN H CD 1 +ATOM 15148 O OE1 . GLN H 1 246 ? 75.306 -29.700 -4.591 1.00 143.33 ? 246 GLN H OE1 1 +ATOM 15149 N NE2 . GLN H 1 246 ? 73.094 -29.510 -4.938 1.00 170.42 ? 246 GLN H NE2 1 +ATOM 15150 N N . ASN H 1 247 ? 74.999 -32.075 0.449 1.00 93.40 ? 247 ASN H N 1 +ATOM 15151 C CA . ASN H 1 247 ? 75.361 -32.800 1.666 1.00 111.07 ? 247 ASN H CA 1 +ATOM 15152 C C . ASN H 1 247 ? 74.598 -34.126 1.768 1.00 107.23 ? 247 ASN H C 1 +ATOM 15153 O O . ASN H 1 247 ? 73.386 -34.164 1.516 1.00 135.56 ? 247 ASN H O 1 +ATOM 15154 C CB . ASN H 1 247 ? 75.041 -31.916 2.881 1.00 124.94 ? 247 ASN H CB 1 +ATOM 15155 C CG . ASN H 1 247 ? 75.878 -32.244 4.092 1.00 152.00 ? 247 ASN H CG 1 +ATOM 15156 O OD1 . ASN H 1 247 ? 75.389 -32.820 5.073 1.00 142.51 ? 247 ASN H OD1 1 +ATOM 15157 N ND2 . ASN H 1 247 ? 77.155 -31.885 4.030 1.00 176.10 ? 247 ASN H ND2 1 +ATOM 15158 N N . ASP H 1 248 ? 75.283 -35.186 2.196 1.00 130.85 ? 248 ASP H N 1 +ATOM 15159 C CA . ASP H 1 248 ? 74.664 -36.524 2.333 1.00 182.31 ? 248 ASP H CA 1 +ATOM 15160 C C . ASP H 1 248 ? 73.366 -36.492 3.154 1.00 223.00 ? 248 ASP H C 1 +ATOM 15161 O O . ASP H 1 248 ? 72.339 -37.076 2.768 1.00 240.40 ? 248 ASP H O 1 +ATOM 15162 C CB . ASP H 1 248 ? 75.630 -37.508 3.015 1.00 172.13 ? 248 ASP H CB 1 +ATOM 15163 C CG . ASP H 1 248 ? 76.799 -37.892 2.136 1.00 171.57 ? 248 ASP H CG 1 +ATOM 15164 O OD1 . ASP H 1 248 ? 76.611 -38.054 0.910 1.00 207.28 ? 248 ASP H OD1 1 +ATOM 15165 O OD2 . ASP H 1 248 ? 77.911 -38.044 2.678 1.00 141.17 ? 248 ASP H OD2 1 +ATOM 15166 N N . ILE H 1 249 ? 73.433 -35.819 4.299 1.00 214.57 ? 249 ILE H N 1 +ATOM 15167 C CA . ILE H 1 249 ? 72.313 -35.750 5.225 1.00 170.20 ? 249 ILE H CA 1 +ATOM 15168 C C . ILE H 1 249 ? 71.156 -34.969 4.594 1.00 144.49 ? 249 ILE H C 1 +ATOM 15169 O O . ILE H 1 249 ? 70.007 -35.438 4.561 1.00 184.20 ? 249 ILE H O 1 +ATOM 15170 C CB . ILE H 1 249 ? 72.747 -35.084 6.546 1.00 158.05 ? 249 ILE H CB 1 +ATOM 15171 C CG1 . ILE H 1 249 ? 73.821 -35.926 7.238 1.00 144.62 ? 249 ILE H CG1 1 +ATOM 15172 C CG2 . ILE H 1 249 ? 71.556 -34.929 7.474 1.00 190.09 ? 249 ILE H CG2 1 +ATOM 15173 C CD1 . ILE H 1 249 ? 74.643 -35.163 8.253 1.00 147.62 ? 249 ILE H CD1 1 +ATOM 15174 N N . LEU H 1 250 ? 71.468 -33.782 4.078 1.00 103.63 ? 250 LEU H N 1 +ATOM 15175 C CA . LEU H 1 250 ? 70.455 -32.928 3.458 1.00 114.42 ? 250 LEU H CA 1 +ATOM 15176 C C . LEU H 1 250 ? 69.714 -33.596 2.289 1.00 138.48 ? 250 LEU H C 1 +ATOM 15177 O O . LEU H 1 250 ? 68.504 -33.403 2.130 1.00 168.53 ? 250 LEU H O 1 +ATOM 15178 C CB . LEU H 1 250 ? 71.075 -31.615 2.989 1.00 104.49 ? 250 LEU H CB 1 +ATOM 15179 C CG . LEU H 1 250 ? 71.318 -30.581 4.087 1.00 114.22 ? 250 LEU H CG 1 +ATOM 15180 C CD1 . LEU H 1 250 ? 72.194 -29.436 3.606 1.00 135.72 ? 250 LEU H CD1 1 +ATOM 15181 C CD2 . LEU H 1 250 ? 69.999 -30.037 4.592 1.00 135.99 ? 250 LEU H CD2 1 +ATOM 15182 N N . VAL H 1 251 ? 70.437 -34.361 1.470 1.00 156.70 ? 251 VAL H N 1 +ATOM 15183 C CA . VAL H 1 251 ? 69.820 -35.063 0.335 1.00 141.55 ? 251 VAL H CA 1 +ATOM 15184 C C . VAL H 1 251 ? 69.064 -36.306 0.798 1.00 158.61 ? 251 VAL H C 1 +ATOM 15185 O O . VAL H 1 251 ? 68.127 -36.751 0.130 1.00 219.98 ? 251 VAL H O 1 +ATOM 15186 C CB . VAL H 1 251 ? 70.845 -35.465 -0.741 1.00 134.02 ? 251 VAL H CB 1 +ATOM 15187 C CG1 . VAL H 1 251 ? 71.623 -34.243 -1.210 1.00 129.21 ? 251 VAL H CG1 1 +ATOM 15188 C CG2 . VAL H 1 251 ? 71.785 -36.562 -0.233 1.00 142.31 ? 251 VAL H CG2 1 +ATOM 15189 N N . LYS H 1 252 ? 69.453 -36.849 1.952 1.00 133.31 ? 252 LYS H N 1 +ATOM 15190 C CA . LYS H 1 252 ? 68.737 -37.974 2.552 1.00 120.78 ? 252 LYS H CA 1 +ATOM 15191 C C . LYS H 1 252 ? 67.327 -37.554 3.015 1.00 142.83 ? 252 LYS H C 1 +ATOM 15192 O O . LYS H 1 252 ? 66.330 -38.211 2.689 1.00 144.09 ? 252 LYS H O 1 +ATOM 15193 C CB . LYS H 1 252 ? 69.560 -38.526 3.716 1.00 109.65 ? 252 LYS H CB 1 +ATOM 15194 C CG . LYS H 1 252 ? 68.926 -39.692 4.453 1.00 116.36 ? 252 LYS H CG 1 +ATOM 15195 C CD . LYS H 1 252 ? 69.826 -40.128 5.603 1.00 120.22 ? 252 LYS H CD 1 +ATOM 15196 C CE . LYS H 1 252 ? 69.043 -40.311 6.900 1.00 126.69 ? 252 LYS H CE 1 +ATOM 15197 N NZ . LYS H 1 252 ? 69.924 -40.485 8.092 1.00 110.93 ? 252 LYS H NZ 1 +ATOM 15198 N N . TYR H 1 253 ? 67.248 -36.408 3.695 1.00 150.90 ? 253 TYR H N 1 +ATOM 15199 C CA . TYR H 1 253 ? 65.970 -35.874 4.196 1.00 111.79 ? 253 TYR H CA 1 +ATOM 15200 C C . TYR H 1 253 ? 65.168 -35.226 3.077 1.00 120.30 ? 253 TYR H C 1 +ATOM 15201 O O . TYR H 1 253 ? 63.937 -35.271 3.077 1.00 150.50 ? 253 TYR H O 1 +ATOM 15202 C CB . TYR H 1 253 ? 66.205 -34.877 5.340 1.00 89.43 ? 253 TYR H CB 1 +ATOM 15203 C CG . TYR H 1 253 ? 66.647 -35.567 6.610 1.00 112.49 ? 253 TYR H CG 1 +ATOM 15204 C CD1 . TYR H 1 253 ? 65.726 -36.181 7.456 1.00 130.86 ? 253 TYR H CD1 1 +ATOM 15205 C CD2 . TYR H 1 253 ? 67.992 -35.725 6.906 1.00 139.57 ? 253 TYR H CD2 1 +ATOM 15206 C CE1 . TYR H 1 253 ? 66.137 -36.866 8.592 1.00 126.57 ? 253 TYR H CE1 1 +ATOM 15207 C CE2 . TYR H 1 253 ? 68.408 -36.430 8.034 1.00 145.44 ? 253 TYR H CE2 1 +ATOM 15208 C CZ . TYR H 1 253 ? 67.470 -36.985 8.878 1.00 120.90 ? 253 TYR H CZ 1 +ATOM 15209 O OH . TYR H 1 253 ? 67.880 -37.658 10.011 1.00 114.77 ? 253 TYR H OH 1 +ATOM 15210 N N . ARG H 1 254 ? 65.868 -34.622 2.120 1.00 119.50 ? 254 ARG H N 1 +ATOM 15211 C CA . ARG H 1 254 ? 65.236 -34.173 0.877 1.00 119.68 ? 254 ARG H CA 1 +ATOM 15212 C C . ARG H 1 254 ? 64.521 -35.342 0.192 1.00 124.36 ? 254 ARG H C 1 +ATOM 15213 O O . ARG H 1 254 ? 63.439 -35.180 -0.367 1.00 127.18 ? 254 ARG H O 1 +ATOM 15214 C CB . ARG H 1 254 ? 66.278 -33.566 -0.075 1.00 124.74 ? 254 ARG H CB 1 +ATOM 15215 C CG . ARG H 1 254 ? 65.672 -32.951 -1.324 1.00 126.07 ? 254 ARG H CG 1 +ATOM 15216 C CD . ARG H 1 254 ? 66.624 -32.005 -2.023 1.00 143.54 ? 254 ARG H CD 1 +ATOM 15217 N NE . ARG H 1 254 ? 66.930 -30.821 -1.219 1.00 135.95 ? 254 ARG H NE 1 +ATOM 15218 C CZ . ARG H 1 254 ? 68.105 -30.569 -0.643 1.00 174.77 ? 254 ARG H CZ 1 +ATOM 15219 N NH1 . ARG H 1 254 ? 69.123 -31.420 -0.754 1.00 205.00 ? 254 ARG H NH1 1 +ATOM 15220 N NH2 . ARG H 1 254 ? 68.270 -29.458 0.063 1.00 160.10 ? 254 ARG H NH2 1 +ATOM 15221 N N . HIS H 1 255 ? 65.167 -36.507 0.196 1.00 138.53 ? 255 HIS H N 1 +ATOM 15222 C CA . HIS H 1 255 ? 64.631 -37.700 -0.455 1.00 154.83 ? 255 HIS H CA 1 +ATOM 15223 C C . HIS H 1 255 ? 63.410 -38.234 0.266 1.00 143.39 ? 255 HIS H C 1 +ATOM 15224 O O . HIS H 1 255 ? 62.503 -38.775 -0.375 1.00 198.46 ? 255 HIS H O 1 +ATOM 15225 C CB . HIS H 1 255 ? 65.709 -38.800 -0.584 1.00 184.68 ? 255 HIS H CB 1 +ATOM 15226 C CG . HIS H 1 255 ? 66.212 -38.983 -1.984 1.00 182.47 ? 255 HIS H CG 1 +ATOM 15227 N ND1 . HIS H 1 255 ? 67.054 -38.078 -2.595 1.00 186.31 ? 255 HIS H ND1 1 +ATOM 15228 C CD2 . HIS H 1 255 ? 65.956 -39.942 -2.905 1.00 166.42 ? 255 HIS H CD2 1 +ATOM 15229 C CE1 . HIS H 1 255 ? 67.311 -38.484 -3.826 1.00 189.96 ? 255 HIS H CE1 1 +ATOM 15230 N NE2 . HIS H 1 255 ? 66.653 -39.610 -4.040 1.00 184.16 ? 255 HIS H NE2 1 +ATOM 15231 N N . MET H 1 256 ? 63.396 -38.120 1.588 1.00 105.63 ? 256 MET H N 1 +ATOM 15232 C CA . MET H 1 256 ? 62.251 -38.616 2.343 1.00 126.38 ? 256 MET H CA 1 +ATOM 15233 C C . MET H 1 256 ? 60.998 -37.778 2.043 1.00 140.85 ? 256 MET H C 1 +ATOM 15234 O O . MET H 1 256 ? 59.861 -38.267 2.192 1.00 120.85 ? 256 MET H O 1 +ATOM 15235 C CB . MET H 1 256 ? 62.567 -38.656 3.839 1.00 142.95 ? 256 MET H CB 1 +ATOM 15236 C CG . MET H 1 256 ? 63.830 -39.444 4.178 1.00 160.63 ? 256 MET H CG 1 +ATOM 15237 S SD . MET H 1 256 ? 63.983 -39.996 5.892 1.00 149.00 ? 256 MET H SD 1 +ATOM 15238 C CE . MET H 1 256 ? 62.678 -41.241 5.951 1.00 85.78 ? 256 MET H CE 1 +ATOM 15239 N N . SER H 1 257 ? 61.210 -36.542 1.577 1.00 149.66 ? 257 SER H N 1 +ATOM 15240 C CA . SER H 1 257 ? 60.127 -35.668 1.112 1.00 144.15 ? 257 SER H CA 1 +ATOM 15241 C C . SER H 1 257 ? 59.704 -36.077 -0.302 1.00 149.91 ? 257 SER H C 1 +ATOM 15242 O O . SER H 1 257 ? 58.798 -36.902 -0.454 1.00 165.65 ? 257 SER H O 1 +ATOM 15243 C CB . SER H 1 257 ? 60.559 -34.192 1.131 1.00 123.18 ? 257 SER H CB 1 +ATOM 15244 O OG . SER H 1 257 ? 61.308 -33.892 2.309 1.00 110.02 ? 257 SER H OG 1 +ATOM 15245 N N . LEU I 1 2 ? 74.414 -54.680 30.781 1.00 144.50 ? 2 LEU I N 1 +ATOM 15246 C CA . LEU I 1 2 ? 72.980 -54.525 30.376 1.00 124.60 ? 2 LEU I CA 1 +ATOM 15247 C C . LEU I 1 2 ? 72.215 -53.683 31.414 1.00 136.13 ? 2 LEU I C 1 +ATOM 15248 O O . LEU I 1 2 ? 71.367 -54.199 32.186 1.00 122.18 ? 2 LEU I O 1 +ATOM 15249 C CB . LEU I 1 2 ? 72.315 -55.887 30.158 1.00 119.56 ? 2 LEU I CB 1 +ATOM 15250 C CG . LEU I 1 2 ? 72.872 -56.802 29.044 1.00 128.32 ? 2 LEU I CG 1 +ATOM 15251 C CD1 . LEU I 1 2 ? 72.066 -58.098 29.014 1.00 133.54 ? 2 LEU I CD1 1 +ATOM 15252 C CD2 . LEU I 1 2 ? 72.915 -56.182 27.641 1.00 121.68 ? 2 LEU I CD2 1 +ATOM 15253 N N . THR I 1 3 ? 72.659 -52.423 31.528 1.00 152.32 ? 3 THR I N 1 +ATOM 15254 C CA . THR I 1 3 ? 71.902 -51.344 32.180 1.00 146.50 ? 3 THR I CA 1 +ATOM 15255 C C . THR I 1 3 ? 72.084 -50.045 31.398 1.00 178.22 ? 3 THR I C 1 +ATOM 15256 O O . THR I 1 3 ? 71.429 -49.030 31.673 1.00 263.63 ? 3 THR I O 1 +ATOM 15257 C CB . THR I 1 3 ? 72.357 -51.059 33.620 1.00 127.24 ? 3 THR I CB 1 +ATOM 15258 O OG1 . THR I 1 3 ? 73.671 -50.484 33.601 1.00 112.17 ? 3 THR I OG1 1 +ATOM 15259 C CG2 . THR I 1 3 ? 72.314 -52.328 34.466 1.00 128.15 ? 3 THR I CG2 1 +ATOM 15260 N N . ALA I 1 4 ? 72.926 -50.078 30.372 1.00 164.28 ? 4 ALA I N 1 +ATOM 15261 C CA . ALA I 1 4 ? 72.780 -49.128 29.281 1.00 180.75 ? 4 ALA I CA 1 +ATOM 15262 C C . ALA I 1 4 ? 71.453 -49.372 28.537 1.00 185.36 ? 4 ALA I C 1 +ATOM 15263 O O . ALA I 1 4 ? 70.789 -50.412 28.705 1.00 203.99 ? 4 ALA I O 1 +ATOM 15264 C CB . ALA I 1 4 ? 74.030 -49.115 28.389 1.00 144.69 ? 4 ALA I CB 1 +ATOM 15265 N N . PRO I 1 5 ? 70.915 -48.306 27.962 1.00 137.40 ? 5 PRO I N 1 +ATOM 15266 C CA . PRO I 1 5 ? 69.579 -48.498 27.458 1.00 109.28 ? 5 PRO I CA 1 +ATOM 15267 C C . PRO I 1 5 ? 69.634 -49.275 26.158 1.00 126.96 ? 5 PRO I C 1 +ATOM 15268 O O . PRO I 1 5 ? 70.726 -49.518 25.637 1.00 123.73 ? 5 PRO I O 1 +ATOM 15269 C CB . PRO I 1 5 ? 69.098 -47.076 27.217 1.00 140.53 ? 5 PRO I CB 1 +ATOM 15270 C CG . PRO I 1 5 ? 70.331 -46.240 27.037 1.00 134.73 ? 5 PRO I CG 1 +ATOM 15271 C CD . PRO I 1 5 ? 71.477 -46.972 27.667 1.00 135.45 ? 5 PRO I CD 1 +ATOM 15272 N N . PRO I 1 6 ? 68.477 -49.755 25.695 1.00 135.65 ? 6 PRO I N 1 +ATOM 15273 C CA . PRO I 1 6 ? 68.391 -50.271 24.336 1.00 132.54 ? 6 PRO I CA 1 +ATOM 15274 C C . PRO I 1 6 ? 68.340 -49.148 23.302 1.00 116.74 ? 6 PRO I C 1 +ATOM 15275 O O . PRO I 1 6 ? 67.828 -48.060 23.559 1.00 105.54 ? 6 PRO I O 1 +ATOM 15276 C CB . PRO I 1 6 ? 67.098 -51.081 24.329 1.00 125.17 ? 6 PRO I CB 1 +ATOM 15277 C CG . PRO I 1 6 ? 66.329 -50.645 25.525 1.00 116.59 ? 6 PRO I CG 1 +ATOM 15278 C CD . PRO I 1 6 ? 67.243 -49.941 26.473 1.00 118.95 ? 6 PRO I CD 1 +ATOM 15279 N N . LYS I 1 7 ? 68.898 -49.413 22.134 1.00 130.84 ? 7 LYS I N 1 +ATOM 15280 C CA . LYS I 1 7 ? 68.972 -48.401 21.079 1.00 136.07 ? 7 LYS I CA 1 +ATOM 15281 C C . LYS I 1 7 ? 67.834 -48.544 20.068 1.00 141.69 ? 7 LYS I C 1 +ATOM 15282 O O . LYS I 1 7 ? 67.104 -49.547 20.074 1.00 99.13 ? 7 LYS I O 1 +ATOM 15283 C CB . LYS I 1 7 ? 70.348 -48.442 20.384 1.00 132.45 ? 7 LYS I CB 1 +ATOM 15284 C CG . LYS I 1 7 ? 71.506 -47.959 21.239 1.00 110.99 ? 7 LYS I CG 1 +ATOM 15285 C CD . LYS I 1 7 ? 72.368 -49.088 21.782 1.00 97.14 ? 7 LYS I CD 1 +ATOM 15286 C CE . LYS I 1 7 ? 73.641 -48.535 22.380 1.00 107.28 ? 7 LYS I CE 1 +ATOM 15287 N NZ . LYS I 1 7 ? 74.154 -49.385 23.493 1.00 128.03 ? 7 LYS I NZ 1 +ATOM 15288 N N . GLU I 1 8 ? 67.727 -47.545 19.183 1.00 170.38 ? 8 GLU I N 1 +ATOM 15289 C CA . GLU I 1 8 ? 66.570 -47.366 18.294 1.00 164.00 ? 8 GLU I CA 1 +ATOM 15290 C C . GLU I 1 8 ? 66.390 -48.487 17.270 1.00 157.54 ? 8 GLU I C 1 +ATOM 15291 O O . GLU I 1 8 ? 67.247 -48.725 16.442 1.00 140.37 ? 8 GLU I O 1 +ATOM 15292 C CB . GLU I 1 8 ? 66.610 -45.984 17.569 1.00 147.09 ? 8 GLU I CB 1 +ATOM 15293 C CG . GLU I 1 8 ? 67.464 -45.855 16.325 1.00 134.61 ? 8 GLU I CG 1 +ATOM 15294 C CD . GLU I 1 8 ? 67.274 -44.518 15.614 1.00 149.89 ? 8 GLU I CD 1 +ATOM 15295 O OE1 . GLU I 1 8 ? 66.108 -44.181 15.243 1.00 187.53 ? 8 GLU I OE1 1 +ATOM 15296 O OE2 . GLU I 1 8 ? 68.295 -43.828 15.369 1.00 137.26 ? 8 GLU I OE2 1 +ATOM 15297 N N . ALA I 1 9 ? 65.271 -49.191 17.384 1.00 159.61 ? 9 ALA I N 1 +ATOM 15298 C CA . ALA I 1 9 ? 64.857 -50.180 16.405 1.00 131.40 ? 9 ALA I CA 1 +ATOM 15299 C C . ALA I 1 9 ? 63.861 -49.541 15.438 1.00 105.18 ? 9 ALA I C 1 +ATOM 15300 O O . ALA I 1 9 ? 62.747 -49.185 15.820 1.00 92.52 ? 9 ALA I O 1 +ATOM 15301 C CB . ALA I 1 9 ? 64.225 -51.361 17.117 1.00 137.75 ? 9 ALA I CB 1 +ATOM 15302 N N . ALA I 1 10 ? 64.284 -49.398 14.188 1.00 97.70 ? 10 ALA I N 1 +ATOM 15303 C CA . ALA I 1 10 ? 63.564 -48.648 13.139 1.00 92.00 ? 10 ALA I CA 1 +ATOM 15304 C C . ALA I 1 10 ? 63.900 -47.168 13.216 1.00 90.26 ? 10 ALA I C 1 +ATOM 15305 O O . ALA I 1 10 ? 64.334 -46.665 14.251 1.00 79.51 ? 10 ALA I O 1 +ATOM 15306 C CB . ALA I 1 10 ? 62.052 -48.870 13.175 1.00 82.03 ? 10 ALA I CB 1 +ATOM 15307 N N . ARG I 1 11 ? 63.766 -46.497 12.073 1.00 115.09 ? 11 ARG I N 1 +ATOM 15308 C CA . ARG I 1 11 ? 64.244 -45.120 11.896 1.00 136.12 ? 11 ARG I CA 1 +ATOM 15309 C C . ARG I 1 11 ? 63.044 -44.168 11.994 1.00 122.28 ? 11 ARG I C 1 +ATOM 15310 O O . ARG I 1 11 ? 61.896 -44.541 11.679 1.00 150.21 ? 11 ARG I O 1 +ATOM 15311 C CB . ARG I 1 11 ? 64.973 -44.951 10.524 1.00 152.28 ? 11 ARG I CB 1 +ATOM 15312 C CG . ARG I 1 11 ? 65.492 -46.291 9.978 1.00 160.66 ? 11 ARG I CG 1 +ATOM 15313 C CD . ARG I 1 11 ? 67.019 -46.134 9.803 1.00 152.01 ? 11 ARG I CD 1 +ATOM 15314 N NE . ARG I 1 11 ? 67.525 -44.797 9.453 1.00 146.56 ? 11 ARG I NE 1 +ATOM 15315 C CZ . ARG I 1 11 ? 68.774 -44.394 9.701 1.00 158.84 ? 11 ARG I CZ 1 +ATOM 15316 N NH1 . ARG I 1 11 ? 69.670 -45.224 10.235 1.00 176.59 ? 11 ARG I NH1 1 +ATOM 15317 N NH2 . ARG I 1 11 ? 69.163 -43.161 9.378 1.00 140.17 ? 11 ARG I NH2 1 +ATOM 15318 N N . PRO I 1 12 ? 63.299 -42.936 12.427 1.00 108.88 ? 12 PRO I N 1 +ATOM 15319 C CA . PRO I 1 12 ? 62.283 -41.929 12.237 1.00 123.43 ? 12 PRO I CA 1 +ATOM 15320 C C . PRO I 1 12 ? 61.995 -41.698 10.742 1.00 119.09 ? 12 PRO I C 1 +ATOM 15321 O O . PRO I 1 12 ? 62.844 -41.199 10.012 1.00 81.33 ? 12 PRO I O 1 +ATOM 15322 C CB . PRO I 1 12 ? 62.891 -40.668 12.894 1.00 124.15 ? 12 PRO I CB 1 +ATOM 15323 C CG . PRO I 1 12 ? 64.081 -41.138 13.653 1.00 119.16 ? 12 PRO I CG 1 +ATOM 15324 C CD . PRO I 1 12 ? 64.547 -42.366 12.943 1.00 123.90 ? 12 PRO I CD 1 +ATOM 15325 N N . THR I 1 13 ? 60.769 -42.018 10.331 1.00 127.19 ? 13 THR I N 1 +ATOM 15326 C CA . THR I 1 13 ? 60.222 -41.552 9.067 1.00 122.72 ? 13 THR I CA 1 +ATOM 15327 C C . THR I 1 13 ? 59.323 -40.321 9.246 1.00 113.47 ? 13 THR I C 1 +ATOM 15328 O O . THR I 1 13 ? 58.858 -40.051 10.352 1.00 162.82 ? 13 THR I O 1 +ATOM 15329 C CB . THR I 1 13 ? 59.383 -42.660 8.441 1.00 122.13 ? 13 THR I CB 1 +ATOM 15330 O OG1 . THR I 1 13 ? 59.078 -42.306 7.087 1.00 170.18 ? 13 THR I OG1 1 +ATOM 15331 C CG2 . THR I 1 13 ? 58.075 -42.932 9.265 1.00 93.14 ? 13 THR I CG2 1 +ATOM 15332 N N . LEU I 1 14 ? 59.072 -39.563 8.185 1.00 100.25 ? 14 LEU I N 1 +ATOM 15333 C CA . LEU I 1 14 ? 58.032 -38.526 8.297 1.00 107.81 ? 14 LEU I CA 1 +ATOM 15334 C C . LEU I 1 14 ? 56.672 -39.218 8.228 1.00 110.28 ? 14 LEU I C 1 +ATOM 15335 O O . LEU I 1 14 ? 56.615 -40.374 7.848 1.00 111.19 ? 14 LEU I O 1 +ATOM 15336 C CB . LEU I 1 14 ? 58.191 -37.391 7.289 1.00 101.17 ? 14 LEU I CB 1 +ATOM 15337 C CG . LEU I 1 14 ? 58.333 -37.743 5.829 1.00 106.93 ? 14 LEU I CG 1 +ATOM 15338 C CD1 . LEU I 1 14 ? 57.708 -36.663 4.964 1.00 114.76 ? 14 LEU I CD1 1 +ATOM 15339 C CD2 . LEU I 1 14 ? 59.801 -37.865 5.497 1.00 129.96 ? 14 LEU I CD2 1 +ATOM 15340 N N . MET I 1 15 ? 55.607 -38.583 8.715 1.00 108.60 ? 15 MET I N 1 +ATOM 15341 C CA . MET I 1 15 ? 54.434 -39.345 9.184 1.00 108.01 ? 15 MET I CA 1 +ATOM 15342 C C . MET I 1 15 ? 53.702 -40.003 8.010 1.00 101.82 ? 15 MET I C 1 +ATOM 15343 O O . MET I 1 15 ? 53.313 -39.325 7.057 1.00 85.99 ? 15 MET I O 1 +ATOM 15344 C CB . MET I 1 15 ? 53.461 -38.472 9.981 1.00 122.68 ? 15 MET I CB 1 +ATOM 15345 C CG . MET I 1 15 ? 52.668 -39.267 11.013 1.00 122.93 ? 15 MET I CG 1 +ATOM 15346 S SD . MET I 1 15 ? 50.944 -38.911 11.332 1.00 127.05 ? 15 MET I SD 1 +ATOM 15347 C CE . MET I 1 15 ? 50.381 -37.854 9.996 1.00 144.69 ? 15 MET I CE 1 +ATOM 15348 N N . PRO I 1 16 ? 53.522 -41.341 8.075 1.00 100.56 ? 16 PRO I N 1 +ATOM 15349 C CA . PRO I 1 16 ? 53.015 -42.172 6.965 1.00 92.10 ? 16 PRO I CA 1 +ATOM 15350 C C . PRO I 1 16 ? 51.577 -41.880 6.534 1.00 101.16 ? 16 PRO I C 1 +ATOM 15351 O O . PRO I 1 16 ? 50.641 -42.579 6.922 1.00 87.56 ? 16 PRO I O 1 +ATOM 15352 C CB . PRO I 1 16 ? 53.137 -43.598 7.516 1.00 91.90 ? 16 PRO I CB 1 +ATOM 15353 C CG . PRO I 1 16 ? 53.122 -43.439 8.994 1.00 94.76 ? 16 PRO I CG 1 +ATOM 15354 C CD . PRO I 1 16 ? 53.860 -42.165 9.251 1.00 95.38 ? 16 PRO I CD 1 +ATOM 15355 N N . ARG I 1 17 ? 51.418 -40.855 5.705 1.00 126.43 ? 17 ARG I N 1 +ATOM 15356 C CA . ARG I 1 17 ? 50.120 -40.528 5.112 1.00 145.79 ? 17 ARG I CA 1 +ATOM 15357 C C . ARG I 1 17 ? 49.980 -41.281 3.800 1.00 121.82 ? 17 ARG I C 1 +ATOM 15358 O O . ARG I 1 17 ? 50.968 -41.503 3.121 1.00 95.88 ? 17 ARG I O 1 +ATOM 15359 C CB . ARG I 1 17 ? 50.019 -39.015 4.873 1.00 178.05 ? 17 ARG I CB 1 +ATOM 15360 C CG . ARG I 1 17 ? 49.503 -38.236 6.075 1.00 172.76 ? 17 ARG I CG 1 +ATOM 15361 C CD . ARG I 1 17 ? 49.794 -36.742 5.990 1.00 145.13 ? 17 ARG I CD 1 +ATOM 15362 N NE . ARG I 1 17 ? 51.182 -36.434 6.337 1.00 152.87 ? 17 ARG I NE 1 +ATOM 15363 C CZ . ARG I 1 17 ? 51.737 -35.235 6.196 1.00 153.12 ? 17 ARG I CZ 1 +ATOM 15364 N NH1 . ARG I 1 17 ? 51.006 -34.233 5.726 1.00 155.21 ? 17 ARG I NH1 1 +ATOM 15365 N NH2 . ARG I 1 17 ? 53.005 -35.032 6.545 1.00 132.10 ? 17 ARG I NH2 1 +ATOM 15366 N N . ALA I 1 18 ? 48.764 -41.698 3.460 1.00 130.31 ? 18 ALA I N 1 +ATOM 15367 C CA . ALA I 1 18 ? 48.554 -42.515 2.259 1.00 126.15 ? 18 ALA I CA 1 +ATOM 15368 C C . ALA I 1 18 ? 47.743 -41.792 1.170 1.00 111.82 ? 18 ALA I C 1 +ATOM 15369 O O . ALA I 1 18 ? 48.180 -40.763 0.650 1.00 76.49 ? 18 ALA I O 1 +ATOM 15370 C CB . ALA I 1 18 ? 47.924 -43.857 2.617 1.00 119.34 ? 18 ALA I CB 1 +ATOM 15371 N N . GLN I 1 19 ? 46.589 -42.351 0.807 1.00 100.63 ? 19 GLN I N 1 +ATOM 15372 C CA . GLN I 1 19 ? 45.943 -42.003 -0.451 1.00 111.74 ? 19 GLN I CA 1 +ATOM 15373 C C . GLN I 1 19 ? 45.415 -40.565 -0.431 1.00 112.75 ? 19 GLN I C 1 +ATOM 15374 O O . GLN I 1 19 ? 45.610 -39.791 -1.386 1.00 105.11 ? 19 GLN I O 1 +ATOM 15375 C CB . GLN I 1 19 ? 44.806 -42.990 -0.754 1.00 111.15 ? 19 GLN I CB 1 +ATOM 15376 C CG . GLN I 1 19 ? 44.164 -42.814 -2.127 1.00 122.61 ? 19 GLN I CG 1 +ATOM 15377 C CD . GLN I 1 19 ? 45.178 -42.854 -3.258 1.00 137.93 ? 19 GLN I CD 1 +ATOM 15378 O OE1 . GLN I 1 19 ? 45.799 -43.890 -3.519 1.00 169.47 ? 19 GLN I OE1 1 +ATOM 15379 N NE2 . GLN I 1 19 ? 45.365 -41.723 -3.928 1.00 145.11 ? 19 GLN I NE2 1 +ATOM 15380 N N . SER I 1 20 ? 44.669 -40.260 0.627 1.00 92.16 ? 20 SER I N 1 +ATOM 15381 C CA . SER I 1 20 ? 44.124 -38.942 0.849 1.00 78.69 ? 20 SER I CA 1 +ATOM 15382 C C . SER I 1 20 ? 45.184 -37.888 0.600 1.00 78.40 ? 20 SER I C 1 +ATOM 15383 O O . SER I 1 20 ? 44.955 -36.912 -0.142 1.00 66.69 ? 20 SER I O 1 +ATOM 15384 C CB . SER I 1 20 ? 43.617 -38.864 2.285 1.00 75.00 ? 20 SER I CB 1 +ATOM 15385 O OG . SER I 1 20 ? 42.713 -39.933 2.568 1.00 75.23 ? 20 SER I OG 1 +ATOM 15386 N N . TYR I 1 21 ? 46.356 -38.112 1.183 1.00 92.06 ? 21 TYR I N 1 +ATOM 15387 C CA . TYR I 1 21 ? 47.504 -37.211 1.001 1.00 137.11 ? 21 TYR I CA 1 +ATOM 15388 C C . TYR I 1 21 ? 47.886 -37.035 -0.478 1.00 125.05 ? 21 TYR I C 1 +ATOM 15389 O O . TYR I 1 21 ? 48.087 -35.904 -0.958 1.00 64.60 ? 21 TYR I O 1 +ATOM 15390 C CB . TYR I 1 21 ? 48.714 -37.732 1.795 1.00 149.94 ? 21 TYR I CB 1 +ATOM 15391 C CG . TYR I 1 21 ? 49.941 -36.845 1.719 1.00 159.22 ? 21 TYR I CG 1 +ATOM 15392 C CD1 . TYR I 1 21 ? 50.028 -35.676 2.465 1.00 147.14 ? 21 TYR I CD1 1 +ATOM 15393 C CD2 . TYR I 1 21 ? 51.012 -37.177 0.896 1.00 189.49 ? 21 TYR I CD2 1 +ATOM 15394 C CE1 . TYR I 1 21 ? 51.131 -34.852 2.374 1.00 160.60 ? 21 TYR I CE1 1 +ATOM 15395 C CE2 . TYR I 1 21 ? 52.128 -36.356 0.809 1.00 184.58 ? 21 TYR I CE2 1 +ATOM 15396 C CZ . TYR I 1 21 ? 52.175 -35.192 1.552 1.00 164.35 ? 21 TYR I CZ 1 +ATOM 15397 O OH . TYR I 1 21 ? 53.244 -34.338 1.460 1.00 178.68 ? 21 TYR I OH 1 +ATOM 15398 N N . LYS I 1 22 ? 48.013 -38.160 -1.180 1.00 122.13 ? 22 LYS I N 1 +ATOM 15399 C CA . LYS I 1 22 ? 48.455 -38.153 -2.572 1.00 113.70 ? 22 LYS I CA 1 +ATOM 15400 C C . LYS I 1 22 ? 47.499 -37.367 -3.455 1.00 116.23 ? 22 LYS I C 1 +ATOM 15401 O O . LYS I 1 22 ? 47.920 -36.636 -4.357 1.00 90.58 ? 22 LYS I O 1 +ATOM 15402 C CB . LYS I 1 22 ? 48.591 -39.584 -3.088 1.00 96.66 ? 22 LYS I CB 1 +ATOM 15403 C CG . LYS I 1 22 ? 49.965 -40.188 -2.853 1.00 101.69 ? 22 LYS I CG 1 +ATOM 15404 C CD . LYS I 1 22 ? 50.936 -39.733 -3.951 1.00 119.81 ? 22 LYS I CD 1 +ATOM 15405 C CE . LYS I 1 22 ? 51.126 -40.850 -4.984 1.00 149.48 ? 22 LYS I CE 1 +ATOM 15406 N NZ . LYS I 1 22 ? 51.792 -42.036 -4.385 1.00 163.80 ? 22 LYS I NZ 1 +ATOM 15407 N N . ASP I 1 23 ? 46.205 -37.537 -3.193 1.00 123.24 ? 23 ASP I N 1 +ATOM 15408 C CA . ASP I 1 23 ? 45.169 -36.767 -3.885 1.00 120.33 ? 23 ASP I CA 1 +ATOM 15409 C C . ASP I 1 23 ? 45.285 -35.288 -3.543 1.00 105.69 ? 23 ASP I C 1 +ATOM 15410 O O . ASP I 1 23 ? 45.210 -34.429 -4.426 1.00 110.47 ? 23 ASP I O 1 +ATOM 15411 C CB . ASP I 1 23 ? 43.779 -37.273 -3.490 1.00 115.26 ? 23 ASP I CB 1 +ATOM 15412 C CG . ASP I 1 23 ? 43.496 -38.660 -4.007 1.00 111.93 ? 23 ASP I CG 1 +ATOM 15413 O OD1 . ASP I 1 23 ? 43.858 -38.925 -5.168 1.00 106.45 ? 23 ASP I OD1 1 +ATOM 15414 O OD2 . ASP I 1 23 ? 42.905 -39.465 -3.251 1.00 99.57 ? 23 ASP I OD2 1 +ATOM 15415 N N . LEU I 1 24 ? 45.467 -35.012 -2.253 1.00 94.44 ? 24 LEU I N 1 +ATOM 15416 C CA . LEU I 1 24 ? 45.467 -33.648 -1.732 1.00 104.90 ? 24 LEU I CA 1 +ATOM 15417 C C . LEU I 1 24 ? 46.636 -32.825 -2.279 1.00 102.40 ? 24 LEU I C 1 +ATOM 15418 O O . LEU I 1 24 ? 46.500 -31.608 -2.530 1.00 68.70 ? 24 LEU I O 1 +ATOM 15419 C CB . LEU I 1 24 ? 45.528 -33.683 -0.200 1.00 120.61 ? 24 LEU I CB 1 +ATOM 15420 C CG . LEU I 1 24 ? 45.531 -32.341 0.559 1.00 133.41 ? 24 LEU I CG 1 +ATOM 15421 C CD1 . LEU I 1 24 ? 44.119 -31.840 0.790 1.00 129.86 ? 24 LEU I CD1 1 +ATOM 15422 C CD2 . LEU I 1 24 ? 46.267 -32.488 1.883 1.00 136.90 ? 24 LEU I CD2 1 +ATOM 15423 N N . THR I 1 25 ? 47.782 -33.486 -2.450 1.00 100.31 ? 25 THR I N 1 +ATOM 15424 C CA . THR I 1 25 ? 48.983 -32.809 -2.930 1.00 102.36 ? 25 THR I CA 1 +ATOM 15425 C C . THR I 1 25 ? 48.912 -32.494 -4.435 1.00 121.15 ? 25 THR I C 1 +ATOM 15426 O O . THR I 1 25 ? 49.226 -31.369 -4.864 1.00 83.12 ? 25 THR I O 1 +ATOM 15427 C CB . THR I 1 25 ? 50.239 -33.644 -2.633 1.00 88.30 ? 25 THR I CB 1 +ATOM 15428 O OG1 . THR I 1 25 ? 50.020 -35.005 -3.021 1.00 70.71 ? 25 THR I OG1 1 +ATOM 15429 C CG2 . THR I 1 25 ? 50.583 -33.575 -1.160 1.00 71.45 ? 25 THR I CG2 1 +ATOM 15430 N N . HIS I 1 26 ? 48.505 -33.490 -5.226 1.00 144.28 ? 26 HIS I N 1 +ATOM 15431 C CA . HIS I 1 26 ? 48.463 -33.372 -6.691 1.00 145.30 ? 26 HIS I CA 1 +ATOM 15432 C C . HIS I 1 26 ? 47.161 -32.704 -7.167 1.00 117.74 ? 26 HIS I C 1 +ATOM 15433 O O . HIS I 1 26 ? 46.588 -33.076 -8.184 1.00 107.84 ? 26 HIS I O 1 +ATOM 15434 C CB . HIS I 1 26 ? 48.652 -34.759 -7.341 1.00 139.24 ? 26 HIS I CB 1 +ATOM 15435 C CG . HIS I 1 26 ? 49.998 -35.368 -7.088 1.00 134.97 ? 26 HIS I CG 1 +ATOM 15436 N ND1 . HIS I 1 26 ? 50.379 -35.834 -5.848 1.00 147.14 ? 26 HIS I ND1 1 +ATOM 15437 C CD2 . HIS I 1 26 ? 51.064 -35.557 -7.903 1.00 135.84 ? 26 HIS I CD2 1 +ATOM 15438 C CE1 . HIS I 1 26 ? 51.622 -36.279 -5.909 1.00 150.81 ? 26 HIS I CE1 1 +ATOM 15439 N NE2 . HIS I 1 26 ? 52.060 -36.126 -7.145 1.00 147.34 ? 26 HIS I NE2 1 +ATOM 15440 N N . LEU I 1 27 ? 46.675 -31.737 -6.403 1.00 105.34 ? 27 LEU I N 1 +ATOM 15441 C CA . LEU I 1 27 ? 45.496 -30.995 -6.803 1.00 106.45 ? 27 LEU I CA 1 +ATOM 15442 C C . LEU I 1 27 ? 45.945 -29.830 -7.668 1.00 86.99 ? 27 LEU I C 1 +ATOM 15443 O O . LEU I 1 27 ? 46.855 -29.097 -7.283 1.00 87.17 ? 27 LEU I O 1 +ATOM 15444 C CB . LEU I 1 27 ? 44.703 -30.504 -5.565 1.00 105.90 ? 27 LEU I CB 1 +ATOM 15445 C CG . LEU I 1 27 ? 43.655 -31.487 -5.028 1.00 110.73 ? 27 LEU I CG 1 +ATOM 15446 C CD1 . LEU I 1 27 ? 43.167 -31.071 -3.657 1.00 104.81 ? 27 LEU I CD1 1 +ATOM 15447 C CD2 . LEU I 1 27 ? 42.473 -31.624 -5.986 1.00 120.00 ? 27 LEU I CD2 1 +ATOM 15448 N N . PRO I 1 28 ? 45.241 -29.591 -8.787 1.00 82.36 ? 28 PRO I N 1 +ATOM 15449 C CA . PRO I 1 28 ? 45.507 -28.417 -9.633 1.00 88.44 ? 28 PRO I CA 1 +ATOM 15450 C C . PRO I 1 28 ? 45.409 -27.086 -8.906 1.00 93.25 ? 28 PRO I C 1 +ATOM 15451 O O . PRO I 1 28 ? 44.427 -26.822 -8.245 1.00 99.41 ? 28 PRO I O 1 +ATOM 15452 C CB . PRO I 1 28 ? 44.419 -28.490 -10.704 1.00 94.04 ? 28 PRO I CB 1 +ATOM 15453 C CG . PRO I 1 28 ? 43.303 -29.249 -10.058 1.00 99.51 ? 28 PRO I CG 1 +ATOM 15454 C CD . PRO I 1 28 ? 43.966 -30.243 -9.144 1.00 92.44 ? 28 PRO I CD 1 +ATOM 15455 N N . ALA I 1 29 ? 46.441 -26.261 -9.015 1.00 132.93 ? 29 ALA I N 1 +ATOM 15456 C CA . ALA I 1 29 ? 46.577 -25.083 -8.151 1.00 144.61 ? 29 ALA I CA 1 +ATOM 15457 C C . ALA I 1 29 ? 45.576 -23.966 -8.532 1.00 131.35 ? 29 ALA I C 1 +ATOM 15458 O O . ALA I 1 29 ? 45.205 -23.818 -9.701 1.00 101.58 ? 29 ALA I O 1 +ATOM 15459 C CB . ALA I 1 29 ? 48.027 -24.571 -8.169 1.00 153.52 ? 29 ALA I CB 1 +ATOM 15460 N N . PRO I 1 30 ? 45.136 -23.182 -7.536 1.00 123.14 ? 30 PRO I N 1 +ATOM 15461 C CA . PRO I 1 30 ? 44.260 -22.028 -7.758 1.00 120.05 ? 30 PRO I CA 1 +ATOM 15462 C C . PRO I 1 30 ? 45.024 -20.820 -8.314 1.00 95.53 ? 30 PRO I C 1 +ATOM 15463 O O . PRO I 1 30 ? 46.248 -20.857 -8.387 1.00 75.42 ? 30 PRO I O 1 +ATOM 15464 C CB . PRO I 1 30 ? 43.756 -21.713 -6.351 1.00 135.30 ? 30 PRO I CB 1 +ATOM 15465 C CG . PRO I 1 30 ? 44.863 -22.150 -5.448 1.00 133.34 ? 30 PRO I CG 1 +ATOM 15466 C CD . PRO I 1 30 ? 45.523 -23.323 -6.118 1.00 124.41 ? 30 PRO I CD 1 +ATOM 15467 N N . THR I 1 31 ? 44.306 -19.738 -8.617 1.00 106.92 ? 31 THR I N 1 +ATOM 15468 C CA . THR I 1 31 ? 44.923 -18.511 -9.157 1.00 121.23 ? 31 THR I CA 1 +ATOM 15469 C C . THR I 1 31 ? 45.815 -17.793 -8.137 1.00 123.53 ? 31 THR I C 1 +ATOM 15470 O O . THR I 1 31 ? 46.758 -17.108 -8.508 1.00 124.59 ? 31 THR I O 1 +ATOM 15471 C CB . THR I 1 31 ? 43.877 -17.499 -9.708 1.00 129.08 ? 31 THR I CB 1 +ATOM 15472 O OG1 . THR I 1 31 ? 42.881 -17.208 -8.718 1.00 134.78 ? 31 THR I OG1 1 +ATOM 15473 C CG2 . THR I 1 31 ? 43.197 -18.043 -10.959 1.00 133.61 ? 31 THR I CG2 1 +ATOM 15474 N N . GLY I 1 32 ? 45.505 -17.956 -6.858 1.00 130.95 ? 32 GLY I N 1 +ATOM 15475 C CA . GLY I 1 32 ? 46.407 -17.562 -5.777 1.00 127.94 ? 32 GLY I CA 1 +ATOM 15476 C C . GLY I 1 32 ? 46.061 -18.364 -4.536 1.00 135.08 ? 32 GLY I C 1 +ATOM 15477 O O . GLY I 1 32 ? 44.938 -18.864 -4.424 1.00 151.77 ? 32 GLY I O 1 +ATOM 15478 N N . LYS I 1 33 ? 47.016 -18.537 -3.620 1.00 123.83 ? 33 LYS I N 1 +ATOM 15479 C CA . LYS I 1 33 ? 46.722 -19.257 -2.380 1.00 113.61 ? 33 LYS I CA 1 +ATOM 15480 C C . LYS I 1 33 ? 45.781 -18.429 -1.493 1.00 131.85 ? 33 LYS I C 1 +ATOM 15481 O O . LYS I 1 33 ? 45.767 -17.201 -1.596 1.00 118.53 ? 33 LYS I O 1 +ATOM 15482 C CB . LYS I 1 33 ? 47.993 -19.604 -1.612 1.00 86.20 ? 33 LYS I CB 1 +ATOM 15483 C CG . LYS I 1 33 ? 48.571 -20.947 -1.965 1.00 91.01 ? 33 LYS I CG 1 +ATOM 15484 C CD . LYS I 1 33 ? 49.909 -21.151 -1.293 1.00 109.28 ? 33 LYS I CD 1 +ATOM 15485 C CE . LYS I 1 33 ? 50.776 -22.130 -2.078 1.00 139.92 ? 33 LYS I CE 1 +ATOM 15486 N NZ . LYS I 1 33 ? 52.158 -22.212 -1.529 1.00 135.11 ? 33 LYS I NZ 1 +ATOM 15487 N N . ILE I 1 34 ? 44.951 -19.106 -0.693 1.00 135.71 ? 34 ILE I N 1 +ATOM 15488 C CA . ILE I 1 34 ? 43.937 -18.436 0.110 1.00 117.22 ? 34 ILE I CA 1 +ATOM 15489 C C . ILE I 1 34 ? 44.384 -18.484 1.571 1.00 99.60 ? 34 ILE I C 1 +ATOM 15490 O O . ILE I 1 34 ? 45.079 -19.407 1.986 1.00 60.00 ? 34 ILE I O 1 +ATOM 15491 C CB . ILE I 1 34 ? 42.527 -19.047 -0.112 1.00 131.67 ? 34 ILE I CB 1 +ATOM 15492 C CG1 . ILE I 1 34 ? 42.042 -18.779 -1.544 1.00 133.57 ? 34 ILE I CG1 1 +ATOM 15493 C CG2 . ILE I 1 34 ? 41.493 -18.450 0.830 1.00 159.26 ? 34 ILE I CG2 1 +ATOM 15494 C CD1 . ILE I 1 34 ? 41.813 -20.045 -2.341 1.00 159.61 ? 34 ILE I CD1 1 +ATOM 15495 N N . PHE I 1 35 ? 44.160 -17.367 2.266 1.00 115.08 ? 35 PHE I N 1 +ATOM 15496 C CA . PHE I 1 35 ? 44.566 -17.184 3.659 1.00 101.41 ? 35 PHE I CA 1 +ATOM 15497 C C . PHE I 1 35 ? 43.528 -17.802 4.564 1.00 102.76 ? 35 PHE I C 1 +ATOM 15498 O O . PHE I 1 35 ? 42.357 -17.427 4.504 1.00 103.30 ? 35 PHE I O 1 +ATOM 15499 C CB . PHE I 1 35 ? 44.636 -15.698 3.988 1.00 96.06 ? 35 PHE I CB 1 +ATOM 15500 C CG . PHE I 1 35 ? 45.952 -15.055 3.684 1.00 73.52 ? 35 PHE I CG 1 +ATOM 15501 C CD1 . PHE I 1 35 ? 47.135 -15.631 4.080 1.00 53.79 ? 35 PHE I CD1 1 +ATOM 15502 C CD2 . PHE I 1 35 ? 45.973 -13.782 3.112 1.00 72.28 ? 35 PHE I CD2 1 +ATOM 15503 C CE1 . PHE I 1 35 ? 48.318 -15.022 3.759 1.00 61.62 ? 35 PHE I CE1 1 +ATOM 15504 C CE2 . PHE I 1 35 ? 47.161 -13.133 2.866 1.00 61.42 ? 35 PHE I CE2 1 +ATOM 15505 C CZ . PHE I 1 35 ? 48.336 -13.757 3.178 1.00 62.20 ? 35 PHE I CZ 1 +ATOM 15506 N N . VAL I 1 36 ? 43.961 -18.694 5.443 1.00 92.48 ? 36 VAL I N 1 +ATOM 15507 C CA . VAL I 1 36 ? 43.006 -19.406 6.266 1.00 89.64 ? 36 VAL I CA 1 +ATOM 15508 C C . VAL I 1 36 ? 43.403 -19.409 7.747 1.00 87.18 ? 36 VAL I C 1 +ATOM 15509 O O . VAL I 1 36 ? 44.588 -19.391 8.084 1.00 100.34 ? 36 VAL I O 1 +ATOM 15510 C CB . VAL I 1 36 ? 42.833 -20.842 5.764 1.00 78.28 ? 36 VAL I CB 1 +ATOM 15511 C CG1 . VAL I 1 36 ? 44.036 -21.693 6.154 1.00 103.69 ? 36 VAL I CG1 1 +ATOM 15512 C CG2 . VAL I 1 36 ? 41.568 -21.436 6.326 1.00 71.78 ? 36 VAL I CG2 1 +ATOM 15513 N N . SER I 1 37 ? 42.403 -19.452 8.625 1.00 65.60 ? 37 SER I N 1 +ATOM 15514 C CA . SER I 1 37 ? 42.645 -19.517 10.042 1.00 52.46 ? 37 SER I CA 1 +ATOM 15515 C C . SER I 1 37 ? 42.043 -20.765 10.591 1.00 46.85 ? 37 SER I C 1 +ATOM 15516 O O . SER I 1 37 ? 40.872 -21.052 10.348 1.00 52.30 ? 37 SER I O 1 +ATOM 15517 C CB . SER I 1 37 ? 41.985 -18.334 10.701 1.00 54.29 ? 37 SER I CB 1 +ATOM 15518 O OG . SER I 1 37 ? 42.722 -17.145 10.473 1.00 80.71 ? 37 SER I OG 1 +ATOM 15519 N N . VAL I 1 38 ? 42.792 -21.503 11.391 1.00 39.05 ? 38 VAL I N 1 +ATOM 15520 C CA . VAL I 1 38 ? 42.144 -22.526 12.193 1.00 51.99 ? 38 VAL I CA 1 +ATOM 15521 C C . VAL I 1 38 ? 42.377 -22.222 13.673 1.00 68.31 ? 38 VAL I C 1 +ATOM 15522 O O . VAL I 1 38 ? 43.543 -22.268 14.136 1.00 112.21 ? 38 VAL I O 1 +ATOM 15523 C CB . VAL I 1 38 ? 42.668 -23.943 11.870 1.00 51.49 ? 38 VAL I CB 1 +ATOM 15524 C CG1 . VAL I 1 38 ? 42.024 -24.982 12.789 1.00 55.00 ? 38 VAL I CG1 1 +ATOM 15525 C CG2 . VAL I 1 38 ? 42.451 -24.316 10.404 1.00 37.15 ? 38 VAL I CG2 1 +ATOM 15526 N N . TYR I 1 39 ? 41.278 -22.025 14.433 1.00 56.15 ? 39 TYR I N 1 +ATOM 15527 C CA . TYR I 1 39 ? 41.360 -21.781 15.878 1.00 51.19 ? 39 TYR I CA 1 +ATOM 15528 C C . TYR I 1 39 ? 41.337 -23.086 16.719 1.00 63.30 ? 39 TYR I C 1 +ATOM 15529 O O . TYR I 1 39 ? 42.261 -23.360 17.509 1.00 60.40 ? 39 TYR I O 1 +ATOM 15530 C CB . TYR I 1 39 ? 40.262 -20.852 16.292 1.00 45.77 ? 39 TYR I CB 1 +ATOM 15531 C CG . TYR I 1 39 ? 40.637 -19.418 16.070 1.00 48.65 ? 39 TYR I CG 1 +ATOM 15532 C CD1 . TYR I 1 39 ? 40.584 -18.853 14.825 1.00 47.42 ? 39 TYR I CD1 1 +ATOM 15533 C CD2 . TYR I 1 39 ? 40.985 -18.591 17.149 1.00 63.68 ? 39 TYR I CD2 1 +ATOM 15534 C CE1 . TYR I 1 39 ? 40.900 -17.511 14.641 1.00 55.45 ? 39 TYR I CE1 1 +ATOM 15535 C CE2 . TYR I 1 39 ? 41.282 -17.236 16.976 1.00 59.08 ? 39 TYR I CE2 1 +ATOM 15536 C CZ . TYR I 1 39 ? 41.250 -16.706 15.714 1.00 53.49 ? 39 TYR I CZ 1 +ATOM 15537 O OH . TYR I 1 39 ? 41.531 -15.375 15.546 1.00 50.51 ? 39 TYR I OH 1 +ATOM 15538 N N . ASN I 1 40 ? 40.370 -23.954 16.455 1.00 69.94 ? 40 ASN I N 1 +ATOM 15539 C CA . ASN I 1 40 ? 40.292 -25.210 17.186 1.00 72.46 ? 40 ASN I CA 1 +ATOM 15540 C C . ASN I 1 40 ? 39.305 -26.210 16.582 1.00 77.14 ? 40 ASN I C 1 +ATOM 15541 O O . ASN I 1 40 ? 38.159 -25.868 16.284 1.00 73.30 ? 40 ASN I O 1 +ATOM 15542 C CB . ASN I 1 40 ? 39.892 -24.934 18.630 1.00 76.25 ? 40 ASN I CB 1 +ATOM 15543 C CG . ASN I 1 40 ? 40.202 -26.099 19.543 1.00 104.84 ? 40 ASN I CG 1 +ATOM 15544 O OD1 . ASN I 1 40 ? 39.300 -26.699 20.123 1.00 107.01 ? 40 ASN I OD1 1 +ATOM 15545 N ND2 . ASN I 1 40 ? 41.488 -26.431 19.671 1.00 116.62 ? 40 ASN I ND2 1 +ATOM 15546 N N . ILE I 1 41 ? 39.743 -27.462 16.456 1.00 68.41 ? 41 ILE I N 1 +ATOM 15547 C CA . ILE I 1 41 ? 38.849 -28.554 16.162 1.00 65.57 ? 41 ILE I CA 1 +ATOM 15548 C C . ILE I 1 41 ? 38.810 -29.523 17.349 1.00 77.43 ? 41 ILE I C 1 +ATOM 15549 O O . ILE I 1 41 ? 39.820 -30.158 17.661 1.00 110.00 ? 41 ILE I O 1 +ATOM 15550 C CB . ILE I 1 41 ? 39.278 -29.292 14.876 1.00 61.73 ? 41 ILE I CB 1 +ATOM 15551 C CG1 . ILE I 1 41 ? 38.819 -28.534 13.627 1.00 66.65 ? 41 ILE I CG1 1 +ATOM 15552 C CG2 . ILE I 1 41 ? 38.597 -30.668 14.808 1.00 87.78 ? 41 ILE I CG2 1 +ATOM 15553 C CD1 . ILE I 1 41 ? 39.536 -27.248 13.340 1.00 54.98 ? 41 ILE I CD1 1 +ATOM 15554 N N . GLN I 1 42 ? 37.635 -29.698 17.966 1.00 75.70 ? 42 GLN I N 1 +ATOM 15555 C CA . GLN I 1 42 ? 37.540 -30.423 19.245 1.00 84.06 ? 42 GLN I CA 1 +ATOM 15556 C C . GLN I 1 42 ? 37.281 -31.909 19.072 1.00 74.28 ? 42 GLN I C 1 +ATOM 15557 O O . GLN I 1 42 ? 36.753 -32.337 18.055 1.00 60.62 ? 42 GLN I O 1 +ATOM 15558 C CB . GLN I 1 42 ? 36.428 -29.856 20.124 1.00 105.17 ? 42 GLN I CB 1 +ATOM 15559 C CG . GLN I 1 42 ? 36.650 -28.426 20.582 1.00 123.54 ? 42 GLN I CG 1 +ATOM 15560 C CD . GLN I 1 42 ? 35.561 -27.478 20.081 1.00 142.90 ? 42 GLN I CD 1 +ATOM 15561 O OE1 . GLN I 1 42 ? 34.520 -27.319 20.727 1.00 136.01 ? 42 GLN I OE1 1 +ATOM 15562 N NE2 . GLN I 1 42 ? 35.777 -26.881 18.906 1.00 120.16 ? 42 GLN I NE2 1 +ATOM 15563 N N . ASP I 1 43 ? 37.658 -32.679 20.091 1.00 67.84 ? 43 ASP I N 1 +ATOM 15564 C CA . ASP I 1 43 ? 37.297 -34.085 20.190 1.00 64.07 ? 43 ASP I CA 1 +ATOM 15565 C C . ASP I 1 43 ? 35.889 -34.217 20.732 1.00 56.56 ? 43 ASP I C 1 +ATOM 15566 O O . ASP I 1 43 ? 35.685 -34.700 21.840 1.00 45.45 ? 43 ASP I O 1 +ATOM 15567 C CB . ASP I 1 43 ? 38.273 -34.811 21.127 1.00 93.48 ? 43 ASP I CB 1 +ATOM 15568 C CG . ASP I 1 43 ? 38.083 -36.339 21.114 1.00 108.56 ? 43 ASP I CG 1 +ATOM 15569 O OD1 . ASP I 1 43 ? 38.042 -36.919 20.012 1.00 160.30 ? 43 ASP I OD1 1 +ATOM 15570 O OD2 . ASP I 1 43 ? 38.007 -36.976 22.192 1.00 99.12 ? 43 ASP I OD2 1 +ATOM 15571 N N . GLU I 1 44 ? 34.910 -33.754 19.953 1.00 82.63 ? 44 GLU I N 1 +ATOM 15572 C CA . GLU I 1 44 ? 33.474 -33.743 20.365 1.00 78.54 ? 44 GLU I CA 1 +ATOM 15573 C C . GLU I 1 44 ? 32.897 -35.170 20.469 1.00 59.55 ? 44 GLU I C 1 +ATOM 15574 O O . GLU I 1 44 ? 31.683 -35.346 20.549 1.00 37.83 ? 44 GLU I O 1 +ATOM 15575 C CB . GLU I 1 44 ? 32.616 -32.858 19.406 1.00 66.05 ? 44 GLU I CB 1 +ATOM 15576 C CG . GLU I 1 44 ? 32.562 -31.369 19.770 1.00 75.02 ? 44 GLU I CG 1 +ATOM 15577 C CD . GLU I 1 44 ? 31.757 -30.509 18.770 1.00 83.29 ? 44 GLU I CD 1 +ATOM 15578 O OE1 . GLU I 1 44 ? 30.640 -30.888 18.346 1.00 66.92 ? 44 GLU I OE1 1 +ATOM 15579 O OE2 . GLU I 1 44 ? 32.199 -29.383 18.459 1.00 98.94 ? 44 GLU I OE2 1 +ATOM 15580 N N . THR I 1 45 ? 33.791 -36.170 20.491 1.00 56.71 ? 45 THR I N 1 +ATOM 15581 C CA . THR I 1 45 ? 33.400 -37.564 20.337 1.00 77.03 ? 45 THR I CA 1 +ATOM 15582 C C . THR I 1 45 ? 32.786 -38.120 21.619 1.00 67.83 ? 45 THR I C 1 +ATOM 15583 O O . THR I 1 45 ? 31.837 -38.893 21.555 1.00 86.31 ? 45 THR I O 1 +ATOM 15584 C CB . THR I 1 45 ? 34.556 -38.471 19.804 1.00 95.34 ? 45 THR I CB 1 +ATOM 15585 O OG1 . THR I 1 45 ? 34.044 -39.739 19.409 1.00 97.30 ? 45 THR I OG1 1 +ATOM 15586 C CG2 . THR I 1 45 ? 35.630 -38.717 20.861 1.00 99.49 ? 45 THR I CG2 1 +ATOM 15587 N N . GLY I 1 46 ? 33.378 -37.805 22.760 1.00 65.27 ? 46 GLY I N 1 +ATOM 15588 C CA . GLY I 1 46 ? 32.839 -38.222 24.075 1.00 89.90 ? 46 GLY I CA 1 +ATOM 15589 C C . GLY I 1 46 ? 33.337 -39.570 24.612 1.00 90.60 ? 46 GLY I C 1 +ATOM 15590 O O . GLY I 1 46 ? 32.700 -40.251 25.416 1.00 83.35 ? 46 GLY I O 1 +ATOM 15591 N N . GLN I 1 47 ? 34.441 -40.030 24.083 1.00 90.64 ? 47 GLN I N 1 +ATOM 15592 C CA . GLN I 1 47 ? 34.678 -41.424 24.144 1.00 79.19 ? 47 GLN I CA 1 +ATOM 15593 C C . GLN I 1 47 ? 36.082 -41.707 24.616 1.00 77.12 ? 47 GLN I C 1 +ATOM 15594 O O . GLN I 1 47 ? 37.037 -41.033 24.225 1.00 63.46 ? 47 GLN I O 1 +ATOM 15595 C CB . GLN I 1 47 ? 34.401 -42.035 22.783 1.00 83.29 ? 47 GLN I CB 1 +ATOM 15596 C CG . GLN I 1 47 ? 32.929 -42.051 22.391 1.00 66.95 ? 47 GLN I CG 1 +ATOM 15597 C CD . GLN I 1 47 ? 32.031 -42.617 23.479 1.00 80.11 ? 47 GLN I CD 1 +ATOM 15598 O OE1 . GLN I 1 47 ? 32.060 -43.806 23.764 1.00 81.94 ? 47 GLN I OE1 1 +ATOM 15599 N NE2 . GLN I 1 47 ? 31.254 -41.768 24.115 1.00 92.67 ? 47 GLN I NE2 1 +ATOM 15600 N N . PHE I 1 48 ? 36.176 -42.713 25.480 1.00 93.24 ? 48 PHE I N 1 +ATOM 15601 C CA . PHE I 1 48 ? 37.446 -43.154 26.060 1.00 102.83 ? 48 PHE I CA 1 +ATOM 15602 C C . PHE I 1 48 ? 37.662 -44.644 25.822 1.00 141.08 ? 48 PHE I C 1 +ATOM 15603 O O . PHE I 1 48 ? 36.723 -45.379 25.449 1.00 220.18 ? 48 PHE I O 1 +ATOM 15604 C CB . PHE I 1 48 ? 37.480 -42.897 27.578 1.00 82.12 ? 48 PHE I CB 1 +ATOM 15605 C CG . PHE I 1 48 ? 37.463 -41.465 27.930 1.00 67.42 ? 48 PHE I CG 1 +ATOM 15606 C CD1 . PHE I 1 48 ? 36.300 -40.740 27.790 1.00 95.18 ? 48 PHE I CD1 1 +ATOM 15607 C CD2 . PHE I 1 48 ? 38.612 -40.817 28.243 1.00 60.61 ? 48 PHE I CD2 1 +ATOM 15608 C CE1 . PHE I 1 48 ? 36.280 -39.387 27.991 1.00 105.79 ? 48 PHE I CE1 1 +ATOM 15609 C CE2 . PHE I 1 48 ? 38.611 -39.471 28.450 1.00 71.05 ? 48 PHE I CE2 1 +ATOM 15610 C CZ . PHE I 1 48 ? 37.442 -38.755 28.343 1.00 93.10 ? 48 PHE I CZ 1 +ATOM 15611 N N . LYS I 1 49 ? 38.894 -45.090 26.084 1.00 113.78 ? 49 LYS I N 1 +ATOM 15612 C CA . LYS I 1 49 ? 39.292 -46.468 25.825 1.00 79.79 ? 49 LYS I CA 1 +ATOM 15613 C C . LYS I 1 49 ? 38.830 -47.342 26.954 1.00 74.35 ? 49 LYS I C 1 +ATOM 15614 O O . LYS I 1 49 ? 38.713 -46.879 28.097 1.00 65.92 ? 49 LYS I O 1 +ATOM 15615 C CB . LYS I 1 49 ? 40.794 -46.581 25.642 1.00 78.98 ? 49 LYS I CB 1 +ATOM 15616 C CG . LYS I 1 49 ? 41.290 -45.861 24.390 1.00 92.13 ? 49 LYS I CG 1 +ATOM 15617 C CD . LYS I 1 49 ? 42.740 -46.097 23.994 1.00 98.70 ? 49 LYS I CD 1 +ATOM 15618 C CE . LYS I 1 49 ? 42.943 -45.450 22.622 1.00 94.60 ? 49 LYS I CE 1 +ATOM 15619 N NZ . LYS I 1 49 ? 44.295 -45.618 22.023 1.00 111.42 ? 49 LYS I NZ 1 +ATOM 15620 N N . PRO I 1 50 ? 38.449 -48.585 26.618 1.00 89.70 ? 50 PRO I N 1 +ATOM 15621 C CA . PRO I 1 50 ? 37.916 -49.535 27.608 1.00 109.25 ? 50 PRO I CA 1 +ATOM 15622 C C . PRO I 1 50 ? 39.044 -50.210 28.360 1.00 134.83 ? 50 PRO I C 1 +ATOM 15623 O O . PRO I 1 50 ? 40.233 -50.064 27.993 1.00 166.51 ? 50 PRO I O 1 +ATOM 15624 C CB . PRO I 1 50 ? 37.162 -50.567 26.761 1.00 107.80 ? 50 PRO I CB 1 +ATOM 15625 C CG . PRO I 1 50 ? 37.848 -50.515 25.430 1.00 130.60 ? 50 PRO I CG 1 +ATOM 15626 C CD . PRO I 1 50 ? 38.316 -49.095 25.241 1.00 104.48 ? 50 PRO I CD 1 +ATOM 15627 N N . TYR I 1 51 ? 38.689 -50.930 29.419 1.00 129.70 ? 51 TYR I N 1 +ATOM 15628 C CA . TYR I 1 51 ? 39.669 -51.736 30.133 1.00 124.06 ? 51 TYR I CA 1 +ATOM 15629 C C . TYR I 1 51 ? 40.421 -52.606 29.128 1.00 144.32 ? 51 TYR I C 1 +ATOM 15630 O O . TYR I 1 51 ? 39.795 -53.177 28.228 1.00 132.97 ? 51 TYR I O 1 +ATOM 15631 C CB . TYR I 1 51 ? 38.992 -52.624 31.174 1.00 99.07 ? 51 TYR I CB 1 +ATOM 15632 C CG . TYR I 1 51 ? 39.990 -53.221 32.122 1.00 125.48 ? 51 TYR I CG 1 +ATOM 15633 C CD1 . TYR I 1 51 ? 40.417 -52.504 33.228 1.00 153.55 ? 51 TYR I CD1 1 +ATOM 15634 C CD2 . TYR I 1 51 ? 40.553 -54.480 31.899 1.00 149.95 ? 51 TYR I CD2 1 +ATOM 15635 C CE1 . TYR I 1 51 ? 41.352 -53.023 34.109 1.00 182.02 ? 51 TYR I CE1 1 +ATOM 15636 C CE2 . TYR I 1 51 ? 41.485 -55.023 32.795 1.00 179.44 ? 51 TYR I CE2 1 +ATOM 15637 C CZ . TYR I 1 51 ? 41.905 -54.264 33.878 1.00 190.54 ? 51 TYR I CZ 1 +ATOM 15638 O OH . TYR I 1 51 ? 42.822 -54.731 34.799 1.00 208.43 ? 51 TYR I OH 1 +ATOM 15639 N N . PRO I 1 52 ? 41.770 -52.699 29.256 1.00 136.79 ? 52 PRO I N 1 +ATOM 15640 C CA . PRO I 1 52 ? 42.644 -52.223 30.337 1.00 108.69 ? 52 PRO I CA 1 +ATOM 15641 C C . PRO I 1 52 ? 43.286 -50.866 30.155 1.00 123.97 ? 52 PRO I C 1 +ATOM 15642 O O . PRO I 1 52 ? 44.249 -50.568 30.873 1.00 155.14 ? 52 PRO I O 1 +ATOM 15643 C CB . PRO I 1 52 ? 43.746 -53.266 30.351 1.00 106.12 ? 52 PRO I CB 1 +ATOM 15644 C CG . PRO I 1 52 ? 43.897 -53.634 28.907 1.00 118.98 ? 52 PRO I CG 1 +ATOM 15645 C CD . PRO I 1 52 ? 42.509 -53.566 28.317 1.00 134.79 ? 52 PRO I CD 1 +ATOM 15646 N N . ALA I 1 53 ? 42.764 -50.031 29.253 1.00 120.52 ? 53 ALA I N 1 +ATOM 15647 C CA . ALA I 1 53 ? 43.307 -48.678 29.114 1.00 116.48 ? 53 ALA I CA 1 +ATOM 15648 C C . ALA I 1 53 ? 43.108 -47.862 30.397 1.00 107.22 ? 53 ALA I C 1 +ATOM 15649 O O . ALA I 1 53 ? 42.256 -48.201 31.251 1.00 72.39 ? 53 ALA I O 1 +ATOM 15650 C CB . ALA I 1 53 ? 42.679 -47.956 27.944 1.00 123.43 ? 53 ALA I CB 1 +ATOM 15651 N N . SER I 1 54 ? 43.897 -46.793 30.538 1.00 111.15 ? 54 SER I N 1 +ATOM 15652 C CA . SER I 1 54 ? 43.622 -45.827 31.588 1.00 97.86 ? 54 SER I CA 1 +ATOM 15653 C C . SER I 1 54 ? 42.232 -45.258 31.369 1.00 117.57 ? 54 SER I C 1 +ATOM 15654 O O . SER I 1 54 ? 41.759 -45.074 30.235 1.00 141.22 ? 54 SER I O 1 +ATOM 15655 C CB . SER I 1 54 ? 44.628 -44.694 31.617 1.00 71.19 ? 54 SER I CB 1 +ATOM 15656 O OG . SER I 1 54 ? 44.088 -43.547 32.268 1.00 62.49 ? 54 SER I OG 1 +ATOM 15657 N N . ASN I 1 55 ? 41.531 -45.064 32.476 1.00 107.07 ? 55 ASN I N 1 +ATOM 15658 C CA . ASN I 1 55 ? 40.194 -44.497 32.443 1.00 100.60 ? 55 ASN I CA 1 +ATOM 15659 C C . ASN I 1 55 ? 40.156 -43.221 31.603 1.00 97.35 ? 55 ASN I C 1 +ATOM 15660 O O . ASN I 1 55 ? 39.131 -42.857 31.000 1.00 101.41 ? 55 ASN I O 1 +ATOM 15661 C CB . ASN I 1 55 ? 39.777 -44.189 33.868 1.00 95.74 ? 55 ASN I CB 1 +ATOM 15662 C CG . ASN I 1 55 ? 38.307 -43.939 33.993 1.00 128.72 ? 55 ASN I CG 1 +ATOM 15663 O OD1 . ASN I 1 55 ? 37.499 -44.316 33.145 1.00 139.03 ? 55 ASN I OD1 1 +ATOM 15664 N ND2 . ASN I 1 55 ? 37.949 -43.325 35.082 1.00 150.08 ? 55 ASN I ND2 1 +ATOM 15665 N N . PHE I 1 56 ? 41.301 -42.537 31.575 1.00 97.51 ? 56 PHE I N 1 +ATOM 15666 C CA . PHE I 1 56 ? 41.405 -41.188 31.016 1.00 88.16 ? 56 PHE I CA 1 +ATOM 15667 C C . PHE I 1 56 ? 41.925 -41.200 29.590 1.00 101.18 ? 56 PHE I C 1 +ATOM 15668 O O . PHE I 1 56 ? 42.155 -40.138 29.003 1.00 88.51 ? 56 PHE I O 1 +ATOM 15669 C CB . PHE I 1 56 ? 42.376 -40.338 31.837 1.00 98.12 ? 56 PHE I CB 1 +ATOM 15670 C CG . PHE I 1 56 ? 41.989 -40.189 33.268 1.00 109.90 ? 56 PHE I CG 1 +ATOM 15671 C CD1 . PHE I 1 56 ? 40.771 -39.629 33.635 1.00 107.60 ? 56 PHE I CD1 1 +ATOM 15672 C CD2 . PHE I 1 56 ? 42.815 -40.667 34.247 1.00 131.75 ? 56 PHE I CD2 1 +ATOM 15673 C CE1 . PHE I 1 56 ? 40.380 -39.573 34.962 1.00 87.32 ? 56 PHE I CE1 1 +ATOM 15674 C CE2 . PHE I 1 56 ? 42.445 -40.568 35.579 1.00 136.50 ? 56 PHE I CE2 1 +ATOM 15675 C CZ . PHE I 1 56 ? 41.223 -40.015 35.936 1.00 87.62 ? 56 PHE I CZ 1 +ATOM 15676 N N . SER I 1 57 ? 42.250 -42.373 29.059 1.00 108.61 ? 57 SER I N 1 +ATOM 15677 C CA . SER I 1 57 ? 42.750 -42.433 27.689 1.00 115.96 ? 57 SER I CA 1 +ATOM 15678 C C . SER I 1 57 ? 41.599 -42.192 26.716 1.00 108.82 ? 57 SER I C 1 +ATOM 15679 O O . SER I 1 57 ? 40.643 -42.978 26.631 1.00 148.39 ? 57 SER I O 1 +ATOM 15680 C CB . SER I 1 57 ? 43.446 -43.774 27.418 1.00 154.26 ? 57 SER I CB 1 +ATOM 15681 O OG . SER I 1 57 ? 44.713 -43.802 28.060 1.00 165.35 ? 57 SER I OG 1 +ATOM 15682 N N . THR I 1 58 ? 41.667 -41.083 26.005 1.00 78.56 ? 58 THR I N 1 +ATOM 15683 C CA . THR I 1 58 ? 40.648 -40.788 25.025 1.00 91.45 ? 58 THR I CA 1 +ATOM 15684 C C . THR I 1 58 ? 40.682 -41.757 23.867 1.00 83.39 ? 58 THR I C 1 +ATOM 15685 O O . THR I 1 58 ? 41.729 -42.236 23.456 1.00 100.53 ? 58 THR I O 1 +ATOM 15686 C CB . THR I 1 58 ? 40.845 -39.384 24.464 1.00 102.70 ? 58 THR I CB 1 +ATOM 15687 O OG1 . THR I 1 58 ? 42.110 -39.296 23.812 1.00 85.74 ? 58 THR I OG1 1 +ATOM 15688 C CG2 . THR I 1 58 ? 40.824 -38.400 25.587 1.00 116.08 ? 58 THR I CG2 1 +ATOM 15689 N N . ALA I 1 59 ? 39.552 -41.951 23.242 1.00 80.60 ? 59 ALA I N 1 +ATOM 15690 C CA . ALA I 1 59 ? 39.556 -42.853 22.124 1.00 102.20 ? 59 ALA I CA 1 +ATOM 15691 C C . ALA I 1 59 ? 40.208 -42.244 20.883 1.00 81.96 ? 59 ALA I C 1 +ATOM 15692 O O . ALA I 1 59 ? 40.599 -42.972 19.975 1.00 75.99 ? 59 ALA I O 1 +ATOM 15693 C CB . ALA I 1 59 ? 38.148 -43.316 21.820 1.00 121.91 ? 59 ALA I CB 1 +ATOM 15694 N N . VAL I 1 60 ? 40.319 -40.926 20.853 1.00 69.29 ? 60 VAL I N 1 +ATOM 15695 C CA . VAL I 1 60 ? 40.738 -40.234 19.666 1.00 82.13 ? 60 VAL I CA 1 +ATOM 15696 C C . VAL I 1 60 ? 41.738 -39.189 20.068 1.00 68.96 ? 60 VAL I C 1 +ATOM 15697 O O . VAL I 1 60 ? 41.577 -38.541 21.099 1.00 77.54 ? 60 VAL I O 1 +ATOM 15698 C CB . VAL I 1 60 ? 39.541 -39.528 19.001 1.00 128.22 ? 60 VAL I CB 1 +ATOM 15699 C CG1 . VAL I 1 60 ? 39.956 -38.743 17.755 1.00 127.97 ? 60 VAL I CG1 1 +ATOM 15700 C CG2 . VAL I 1 60 ? 38.447 -40.532 18.640 1.00 161.49 ? 60 VAL I CG2 1 +ATOM 15701 N N . PRO I 1 61 ? 42.737 -38.954 19.222 1.00 60.14 ? 61 PRO I N 1 +ATOM 15702 C CA . PRO I 1 61 ? 43.775 -38.021 19.637 1.00 71.15 ? 61 PRO I CA 1 +ATOM 15703 C C . PRO I 1 61 ? 43.258 -36.603 19.588 1.00 75.35 ? 61 PRO I C 1 +ATOM 15704 O O . PRO I 1 61 ? 42.404 -36.285 18.747 1.00 43.34 ? 61 PRO I O 1 +ATOM 15705 C CB . PRO I 1 61 ? 44.870 -38.206 18.595 1.00 74.54 ? 61 PRO I CB 1 +ATOM 15706 C CG . PRO I 1 61 ? 44.184 -38.865 17.440 1.00 71.47 ? 61 PRO I CG 1 +ATOM 15707 C CD . PRO I 1 61 ? 43.157 -39.745 18.068 1.00 73.50 ? 61 PRO I CD 1 +ATOM 15708 N N . GLN I 1 62 ? 43.777 -35.766 20.494 1.00 69.58 ? 62 GLN I N 1 +ATOM 15709 C CA . GLN I 1 62 ? 43.252 -34.421 20.682 1.00 65.63 ? 62 GLN I CA 1 +ATOM 15710 C C . GLN I 1 62 ? 44.012 -33.481 19.802 1.00 53.41 ? 62 GLN I C 1 +ATOM 15711 O O . GLN I 1 62 ? 44.210 -32.334 20.162 1.00 87.65 ? 62 GLN I O 1 +ATOM 15712 C CB . GLN I 1 62 ? 43.411 -33.968 22.148 1.00 87.91 ? 62 GLN I CB 1 +ATOM 15713 C CG . GLN I 1 62 ? 42.871 -34.940 23.193 1.00 86.05 ? 62 GLN I CG 1 +ATOM 15714 C CD . GLN I 1 62 ? 41.399 -35.218 23.004 1.00 80.08 ? 62 GLN I CD 1 +ATOM 15715 O OE1 . GLN I 1 62 ? 40.549 -34.402 23.347 1.00 78.30 ? 62 GLN I OE1 1 +ATOM 15716 N NE2 . GLN I 1 62 ? 41.091 -36.347 22.396 1.00 89.67 ? 62 GLN I NE2 1 +ATOM 15717 N N . SER I 1 63 ? 44.365 -33.933 18.625 1.00 53.50 ? 63 SER I N 1 +ATOM 15718 C CA . SER I 1 63 ? 45.352 -33.256 17.827 1.00 69.42 ? 63 SER I CA 1 +ATOM 15719 C C . SER I 1 63 ? 44.800 -32.844 16.455 1.00 93.26 ? 63 SER I C 1 +ATOM 15720 O O . SER I 1 63 ? 45.552 -32.403 15.569 1.00 104.54 ? 63 SER I O 1 +ATOM 15721 C CB . SER I 1 63 ? 46.563 -34.178 17.666 1.00 95.80 ? 63 SER I CB 1 +ATOM 15722 O OG . SER I 1 63 ? 46.270 -35.391 16.981 1.00 109.30 ? 63 SER I OG 1 +ATOM 15723 N N . ALA I 1 64 ? 43.481 -32.940 16.299 1.00 81.54 ? 64 ALA I N 1 +ATOM 15724 C CA . ALA I 1 64 ? 42.849 -32.722 15.011 1.00 91.37 ? 64 ALA I CA 1 +ATOM 15725 C C . ALA I 1 64 ? 43.169 -31.346 14.389 1.00 74.99 ? 64 ALA I C 1 +ATOM 15726 O O . ALA I 1 64 ? 43.362 -31.212 13.163 1.00 77.26 ? 64 ALA I O 1 +ATOM 15727 C CB . ALA I 1 64 ? 41.350 -32.902 15.159 1.00 109.98 ? 64 ALA I CB 1 +ATOM 15728 N N . THR I 1 65 ? 43.165 -30.330 15.230 1.00 60.74 ? 65 THR I N 1 +ATOM 15729 C CA . THR I 1 65 ? 43.446 -28.981 14.801 1.00 67.10 ? 65 THR I CA 1 +ATOM 15730 C C . THR I 1 65 ? 44.706 -28.917 13.952 1.00 64.52 ? 65 THR I C 1 +ATOM 15731 O O . THR I 1 65 ? 44.745 -28.265 12.917 1.00 45.58 ? 65 THR I O 1 +ATOM 15732 C CB . THR I 1 65 ? 43.641 -28.091 16.035 1.00 91.53 ? 65 THR I CB 1 +ATOM 15733 O OG1 . THR I 1 65 ? 42.710 -28.489 17.051 1.00 116.96 ? 65 THR I OG1 1 +ATOM 15734 C CG2 . THR I 1 65 ? 43.460 -26.605 15.690 1.00 78.41 ? 65 THR I CG2 1 +ATOM 15735 N N . ALA I 1 66 ? 45.782 -29.492 14.471 1.00 100.82 ? 66 ALA I N 1 +ATOM 15736 C CA . ALA I 1 66 ? 47.070 -29.339 13.838 1.00 123.74 ? 66 ALA I CA 1 +ATOM 15737 C C . ALA I 1 66 ? 47.055 -30.130 12.529 1.00 99.78 ? 66 ALA I C 1 +ATOM 15738 O O . ALA I 1 66 ? 47.734 -29.743 11.555 1.00 114.41 ? 66 ALA I O 1 +ATOM 15739 C CB . ALA I 1 66 ? 48.185 -29.789 14.789 1.00 126.33 ? 66 ALA I CB 1 +ATOM 15740 N N . MET I 1 67 ? 46.338 -31.258 12.537 1.00 66.43 ? 67 MET I N 1 +ATOM 15741 C CA . MET I 1 67 ? 46.266 -32.112 11.350 1.00 91.21 ? 67 MET I CA 1 +ATOM 15742 C C . MET I 1 67 ? 45.556 -31.357 10.227 1.00 93.83 ? 67 MET I C 1 +ATOM 15743 O O . MET I 1 67 ? 45.973 -31.386 9.061 1.00 77.89 ? 67 MET I O 1 +ATOM 15744 C CB . MET I 1 67 ? 45.514 -33.408 11.647 1.00 98.41 ? 67 MET I CB 1 +ATOM 15745 C CG . MET I 1 67 ? 46.242 -34.419 12.516 1.00 98.36 ? 67 MET I CG 1 +ATOM 15746 S SD . MET I 1 67 ? 45.123 -35.724 13.067 1.00 128.10 ? 67 MET I SD 1 +ATOM 15747 C CE . MET I 1 67 ? 46.261 -36.841 13.886 1.00 143.35 ? 67 MET I CE 1 +ATOM 15748 N N . LEU I 1 68 ? 44.510 -30.631 10.598 1.00 89.15 ? 68 LEU I N 1 +ATOM 15749 C CA . LEU I 1 68 ? 43.776 -29.847 9.622 1.00 81.57 ? 68 LEU I CA 1 +ATOM 15750 C C . LEU I 1 68 ? 44.652 -28.750 9.058 1.00 96.73 ? 68 LEU I C 1 +ATOM 15751 O O . LEU I 1 68 ? 44.625 -28.506 7.860 1.00 109.61 ? 68 LEU I O 1 +ATOM 15752 C CB . LEU I 1 68 ? 42.527 -29.211 10.232 1.00 95.57 ? 68 LEU I CB 1 +ATOM 15753 C CG . LEU I 1 68 ? 41.838 -28.186 9.314 1.00 89.37 ? 68 LEU I CG 1 +ATOM 15754 C CD1 . LEU I 1 68 ? 41.271 -28.876 8.084 1.00 94.87 ? 68 LEU I CD1 1 +ATOM 15755 C CD2 . LEU I 1 68 ? 40.739 -27.420 10.028 1.00 95.30 ? 68 LEU I CD2 1 +ATOM 15756 N N . VAL I 1 69 ? 45.385 -28.044 9.925 1.00 103.29 ? 69 VAL I N 1 +ATOM 15757 C CA . VAL I 1 69 ? 46.233 -26.943 9.467 1.00 85.24 ? 69 VAL I CA 1 +ATOM 15758 C C . VAL I 1 69 ? 47.241 -27.502 8.478 1.00 90.57 ? 69 VAL I C 1 +ATOM 15759 O O . VAL I 1 69 ? 47.519 -26.906 7.432 1.00 91.41 ? 69 VAL I O 1 +ATOM 15760 C CB . VAL I 1 69 ? 46.974 -26.245 10.625 1.00 65.56 ? 69 VAL I CB 1 +ATOM 15761 C CG1 . VAL I 1 69 ? 47.965 -25.238 10.066 1.00 60.74 ? 69 VAL I CG1 1 +ATOM 15762 C CG2 . VAL I 1 69 ? 46.009 -25.507 11.539 1.00 102.09 ? 69 VAL I CG2 1 +ATOM 15763 N N . THR I 1 70 ? 47.810 -28.648 8.830 1.00 88.58 ? 70 THR I N 1 +ATOM 15764 C CA . THR I 1 70 ? 48.826 -29.273 7.999 1.00 83.86 ? 70 THR I CA 1 +ATOM 15765 C C . THR I 1 70 ? 48.226 -29.661 6.661 1.00 98.58 ? 70 THR I C 1 +ATOM 15766 O O . THR I 1 70 ? 48.852 -29.462 5.603 1.00 112.51 ? 70 THR I O 1 +ATOM 15767 C CB . THR I 1 70 ? 49.416 -30.497 8.713 1.00 78.08 ? 70 THR I CB 1 +ATOM 15768 O OG1 . THR I 1 70 ? 49.937 -30.078 9.981 1.00 90.51 ? 70 THR I OG1 1 +ATOM 15769 C CG2 . THR I 1 70 ? 50.537 -31.128 7.886 1.00 88.96 ? 70 THR I CG2 1 +ATOM 15770 N N . ALA I 1 71 ? 47.040 -30.273 6.698 1.00 92.45 ? 71 ALA I N 1 +ATOM 15771 C CA . ALA I 1 71 ? 46.377 -30.684 5.452 1.00 97.63 ? 71 ALA I CA 1 +ATOM 15772 C C . ALA I 1 71 ? 46.089 -29.453 4.572 1.00 94.69 ? 71 ALA I C 1 +ATOM 15773 O O . ALA I 1 71 ? 46.257 -29.483 3.350 1.00 57.60 ? 71 ALA I O 1 +ATOM 15774 C CB . ALA I 1 71 ? 45.103 -31.448 5.759 1.00 90.80 ? 71 ALA I CB 1 +ATOM 15775 N N . LEU I 1 72 ? 45.661 -28.366 5.211 1.00 110.22 ? 72 LEU I N 1 +ATOM 15776 C CA . LEU I 1 72 ? 45.363 -27.123 4.489 1.00 128.01 ? 72 LEU I CA 1 +ATOM 15777 C C . LEU I 1 72 ? 46.615 -26.579 3.829 1.00 148.82 ? 72 LEU I C 1 +ATOM 15778 O O . LEU I 1 72 ? 46.529 -25.869 2.833 1.00 144.14 ? 72 LEU I O 1 +ATOM 15779 C CB . LEU I 1 72 ? 44.783 -26.064 5.431 1.00 123.60 ? 72 LEU I CB 1 +ATOM 15780 C CG . LEU I 1 72 ? 43.385 -26.353 5.970 1.00 115.82 ? 72 LEU I CG 1 +ATOM 15781 C CD1 . LEU I 1 72 ? 43.110 -25.480 7.183 1.00 89.45 ? 72 LEU I CD1 1 +ATOM 15782 C CD2 . LEU I 1 72 ? 42.325 -26.136 4.907 1.00 133.53 ? 72 LEU I CD2 1 +ATOM 15783 N N . LYS I 1 73 ? 47.779 -26.896 4.399 1.00 141.41 ? 73 LYS I N 1 +ATOM 15784 C CA . LYS I 1 73 ? 49.043 -26.424 3.831 1.00 124.33 ? 73 LYS I CA 1 +ATOM 15785 C C . LYS I 1 73 ? 49.522 -27.316 2.717 1.00 114.76 ? 73 LYS I C 1 +ATOM 15786 O O . LYS I 1 73 ? 49.923 -26.828 1.656 1.00 127.72 ? 73 LYS I O 1 +ATOM 15787 C CB . LYS I 1 73 ? 50.136 -26.334 4.887 1.00 129.30 ? 73 LYS I CB 1 +ATOM 15788 C CG . LYS I 1 73 ? 51.373 -25.566 4.419 1.00 128.74 ? 73 LYS I CG 1 +ATOM 15789 C CD . LYS I 1 73 ? 52.444 -25.486 5.514 1.00 142.09 ? 73 LYS I CD 1 +ATOM 15790 C CE . LYS I 1 73 ? 53.848 -25.365 4.935 1.00 162.41 ? 73 LYS I CE 1 +ATOM 15791 N NZ . LYS I 1 73 ? 54.502 -24.057 5.223 1.00 165.57 ? 73 LYS I NZ 1 +ATOM 15792 N N . ASP I 1 74 ? 49.466 -28.625 2.945 1.00 111.62 ? 74 ASP I N 1 +ATOM 15793 C CA . ASP I 1 74 ? 49.945 -29.589 1.952 1.00 132.78 ? 74 ASP I CA 1 +ATOM 15794 C C . ASP I 1 74 ? 49.188 -29.486 0.622 1.00 140.03 ? 74 ASP I C 1 +ATOM 15795 O O . ASP I 1 74 ? 49.749 -29.785 -0.442 1.00 139.30 ? 74 ASP I O 1 +ATOM 15796 C CB . ASP I 1 74 ? 49.839 -31.017 2.493 1.00 122.34 ? 74 ASP I CB 1 +ATOM 15797 C CG . ASP I 1 74 ? 50.814 -31.299 3.641 1.00 117.16 ? 74 ASP I CG 1 +ATOM 15798 O OD1 . ASP I 1 74 ? 51.903 -30.678 3.717 1.00 114.38 ? 74 ASP I OD1 1 +ATOM 15799 O OD2 . ASP I 1 74 ? 50.475 -32.171 4.475 1.00 120.73 ? 74 ASP I OD2 1 +ATOM 15800 N N . SER I 1 75 ? 47.928 -29.046 0.688 1.00 132.20 ? 75 SER I N 1 +ATOM 15801 C CA . SER I 1 75 ? 47.068 -28.941 -0.499 1.00 135.24 ? 75 SER I CA 1 +ATOM 15802 C C . SER I 1 75 ? 47.583 -27.920 -1.521 1.00 126.84 ? 75 SER I C 1 +ATOM 15803 O O . SER I 1 75 ? 47.269 -28.010 -2.708 1.00 104.88 ? 75 SER I O 1 +ATOM 15804 C CB . SER I 1 75 ? 45.637 -28.568 -0.096 1.00 126.21 ? 75 SER I CB 1 +ATOM 15805 O OG . SER I 1 75 ? 45.490 -27.163 0.023 1.00 107.84 ? 75 SER I OG 1 +ATOM 15806 N N . ARG I 1 76 ? 48.352 -26.949 -1.036 1.00 132.02 ? 76 ARG I N 1 +ATOM 15807 C CA . ARG I 1 76 ? 48.878 -25.853 -1.845 1.00 127.19 ? 76 ARG I CA 1 +ATOM 15808 C C . ARG I 1 76 ? 47.744 -25.036 -2.421 1.00 102.54 ? 76 ARG I C 1 +ATOM 15809 O O . ARG I 1 76 ? 47.839 -24.503 -3.528 1.00 95.11 ? 76 ARG I O 1 +ATOM 15810 C CB . ARG I 1 76 ? 49.788 -26.362 -2.953 1.00 143.60 ? 76 ARG I CB 1 +ATOM 15811 C CG . ARG I 1 76 ? 51.023 -27.122 -2.470 1.00 148.19 ? 76 ARG I CG 1 +ATOM 15812 C CD . ARG I 1 76 ? 51.877 -27.553 -3.663 1.00 155.63 ? 76 ARG I CD 1 +ATOM 15813 N NE . ARG I 1 76 ? 51.231 -28.593 -4.465 1.00 150.68 ? 76 ARG I NE 1 +ATOM 15814 C CZ . ARG I 1 76 ? 50.463 -28.383 -5.537 1.00 139.00 ? 76 ARG I CZ 1 +ATOM 15815 N NH1 . ARG I 1 76 ? 50.241 -27.155 -6.007 1.00 125.24 ? 76 ARG I NH1 1 +ATOM 15816 N NH2 . ARG I 1 76 ? 49.896 -29.419 -6.141 1.00 137.67 ? 76 ARG I NH2 1 +ATOM 15817 N N . TRP I 1 77 ? 46.699 -24.882 -1.613 1.00 90.86 ? 77 TRP I N 1 +ATOM 15818 C CA . TRP I 1 77 ? 45.621 -23.938 -1.890 1.00 99.09 ? 77 TRP I CA 1 +ATOM 15819 C C . TRP I 1 77 ? 45.556 -22.819 -0.841 1.00 88.51 ? 77 TRP I C 1 +ATOM 15820 O O . TRP I 1 77 ? 45.200 -21.677 -1.154 1.00 59.47 ? 77 TRP I O 1 +ATOM 15821 C CB . TRP I 1 77 ? 44.298 -24.690 -1.911 1.00 111.02 ? 77 TRP I CB 1 +ATOM 15822 C CG . TRP I 1 77 ? 43.907 -25.177 -3.258 1.00 112.33 ? 77 TRP I CG 1 +ATOM 15823 C CD1 . TRP I 1 77 ? 44.404 -26.267 -3.911 1.00 125.99 ? 77 TRP I CD1 1 +ATOM 15824 C CD2 . TRP I 1 77 ? 42.891 -24.633 -4.098 1.00 96.69 ? 77 TRP I CD2 1 +ATOM 15825 N NE1 . TRP I 1 77 ? 43.757 -26.434 -5.105 1.00 124.98 ? 77 TRP I NE1 1 +ATOM 15826 C CE2 . TRP I 1 77 ? 42.822 -25.441 -5.243 1.00 107.28 ? 77 TRP I CE2 1 +ATOM 15827 C CE3 . TRP I 1 77 ? 42.025 -23.546 -3.989 1.00 96.66 ? 77 TRP I CE3 1 +ATOM 15828 C CZ2 . TRP I 1 77 ? 41.933 -25.187 -6.279 1.00 110.99 ? 77 TRP I CZ2 1 +ATOM 15829 C CZ3 . TRP I 1 77 ? 41.124 -23.312 -5.012 1.00 108.36 ? 77 TRP I CZ3 1 +ATOM 15830 C CH2 . TRP I 1 77 ? 41.091 -24.121 -6.144 1.00 105.55 ? 77 TRP I CH2 1 +ATOM 15831 N N . PHE I 1 78 ? 45.920 -23.163 0.395 1.00 100.22 ? 78 PHE I N 1 +ATOM 15832 C CA . PHE I 1 78 ? 45.798 -22.263 1.541 1.00 108.26 ? 78 PHE I CA 1 +ATOM 15833 C C . PHE I 1 78 ? 47.144 -21.983 2.241 1.00 120.41 ? 78 PHE I C 1 +ATOM 15834 O O . PHE I 1 78 ? 47.985 -22.864 2.366 1.00 101.44 ? 78 PHE I O 1 +ATOM 15835 C CB . PHE I 1 78 ? 44.889 -22.896 2.569 1.00 97.23 ? 78 PHE I CB 1 +ATOM 15836 C CG . PHE I 1 78 ? 43.572 -23.292 2.030 1.00 92.71 ? 78 PHE I CG 1 +ATOM 15837 C CD1 . PHE I 1 78 ? 42.607 -22.325 1.750 1.00 95.49 ? 78 PHE I CD1 1 +ATOM 15838 C CD2 . PHE I 1 78 ? 43.268 -24.632 1.835 1.00 76.31 ? 78 PHE I CD2 1 +ATOM 15839 C CE1 . PHE I 1 78 ? 41.362 -22.696 1.268 1.00 102.70 ? 78 PHE I CE1 1 +ATOM 15840 C CE2 . PHE I 1 78 ? 42.022 -25.007 1.362 1.00 74.11 ? 78 PHE I CE2 1 +ATOM 15841 C CZ . PHE I 1 78 ? 41.069 -24.042 1.073 1.00 76.75 ? 78 PHE I CZ 1 +ATOM 15842 N N . ILE I 1 79 ? 47.307 -20.749 2.701 1.00 112.05 ? 79 ILE I N 1 +ATOM 15843 C CA . ILE I 1 79 ? 48.323 -20.388 3.665 1.00 79.12 ? 79 ILE I CA 1 +ATOM 15844 C C . ILE I 1 79 ? 47.619 -20.374 5.008 1.00 86.68 ? 79 ILE I C 1 +ATOM 15845 O O . ILE I 1 79 ? 46.599 -19.684 5.202 1.00 86.55 ? 79 ILE I O 1 +ATOM 15846 C CB . ILE I 1 79 ? 48.842 -18.969 3.415 1.00 99.21 ? 79 ILE I CB 1 +ATOM 15847 C CG1 . ILE I 1 79 ? 49.217 -18.784 1.946 1.00 101.67 ? 79 ILE I CG1 1 +ATOM 15848 C CG2 . ILE I 1 79 ? 50.042 -18.661 4.305 1.00 121.28 ? 79 ILE I CG2 1 +ATOM 15849 C CD1 . ILE I 1 79 ? 49.208 -17.331 1.479 1.00 93.05 ? 79 ILE I CD1 1 +ATOM 15850 N N . PRO I 1 80 ? 48.114 -21.177 5.936 1.00 99.37 ? 80 PRO I N 1 +ATOM 15851 C CA . PRO I 1 80 ? 47.500 -21.103 7.244 1.00 107.84 ? 80 PRO I CA 1 +ATOM 15852 C C . PRO I 1 80 ? 48.143 -20.030 8.107 1.00 89.98 ? 80 PRO I C 1 +ATOM 15853 O O . PRO I 1 80 ? 49.355 -19.960 8.194 1.00 59.25 ? 80 PRO I O 1 +ATOM 15854 C CB . PRO I 1 80 ? 47.732 -22.516 7.820 1.00 91.80 ? 80 PRO I CB 1 +ATOM 15855 C CG . PRO I 1 80 ? 47.936 -23.362 6.623 1.00 82.28 ? 80 PRO I CG 1 +ATOM 15856 C CD . PRO I 1 80 ? 48.750 -22.478 5.727 1.00 93.15 ? 80 PRO I CD 1 +ATOM 15857 N N . LEU I 1 81 ? 47.308 -19.223 8.747 1.00 93.06 ? 81 LEU I N 1 +ATOM 15858 C CA . LEU I 1 81 ? 47.765 -18.284 9.749 1.00 86.86 ? 81 LEU I CA 1 +ATOM 15859 C C . LEU I 1 81 ? 47.642 -18.877 11.140 1.00 87.55 ? 81 LEU I C 1 +ATOM 15860 O O . LEU I 1 81 ? 46.719 -19.694 11.415 1.00 121.79 ? 81 LEU I O 1 +ATOM 15861 C CB . LEU I 1 81 ? 46.944 -17.034 9.653 1.00 99.08 ? 81 LEU I CB 1 +ATOM 15862 C CG . LEU I 1 81 ? 46.948 -16.490 8.227 1.00 135.32 ? 81 LEU I CG 1 +ATOM 15863 C CD1 . LEU I 1 81 ? 46.021 -15.308 8.174 1.00 127.82 ? 81 LEU I CD1 1 +ATOM 15864 C CD2 . LEU I 1 81 ? 48.347 -16.083 7.834 1.00 172.11 ? 81 LEU I CD2 1 +ATOM 15865 N N . GLU I 1 82 ? 48.640 -18.575 11.960 1.00 75.04 ? 82 GLU I N 1 +ATOM 15866 C CA . GLU I 1 82 ? 48.795 -19.252 13.253 1.00 113.56 ? 82 GLU I CA 1 +ATOM 15867 C C . GLU I 1 82 ? 47.887 -18.578 14.250 1.00 125.13 ? 82 GLU I C 1 +ATOM 15868 O O . GLU I 1 82 ? 48.148 -17.448 14.686 1.00 143.02 ? 82 GLU I O 1 +ATOM 15869 C CB . GLU I 1 82 ? 50.268 -19.262 13.762 1.00 133.30 ? 82 GLU I CB 1 +ATOM 15870 C CG . GLU I 1 82 ? 50.499 -19.879 15.159 1.00 111.28 ? 82 GLU I CG 1 +ATOM 15871 C CD . GLU I 1 82 ? 50.326 -21.410 15.230 1.00 113.13 ? 82 GLU I CD 1 +ATOM 15872 O OE1 . GLU I 1 82 ? 49.300 -21.973 14.722 1.00 191.41 ? 82 GLU I OE1 1 +ATOM 15873 O OE2 . GLU I 1 82 ? 51.191 -22.072 15.836 1.00 69.15 ? 82 GLU I OE2 1 +ATOM 15874 N N . ARG I 1 83 ? 46.873 -19.332 14.665 1.00 109.95 ? 83 ARG I N 1 +ATOM 15875 C CA . ARG I 1 83 ? 45.985 -18.913 15.728 1.00 95.95 ? 83 ARG I CA 1 +ATOM 15876 C C . ARG I 1 83 ? 45.903 -19.924 16.885 1.00 84.48 ? 83 ARG I C 1 +ATOM 15877 O O . ARG I 1 83 ? 45.511 -19.561 17.991 1.00 92.93 ? 83 ARG I O 1 +ATOM 15878 C CB . ARG I 1 83 ? 44.593 -18.639 15.153 1.00 91.76 ? 83 ARG I CB 1 +ATOM 15879 C CG . ARG I 1 83 ? 44.561 -17.615 14.031 1.00 70.70 ? 83 ARG I CG 1 +ATOM 15880 C CD . ARG I 1 83 ? 44.874 -16.212 14.505 1.00 55.10 ? 83 ARG I CD 1 +ATOM 15881 N NE . ARG I 1 83 ? 44.567 -15.291 13.429 1.00 50.72 ? 83 ARG I NE 1 +ATOM 15882 C CZ . ARG I 1 83 ? 45.454 -14.744 12.619 1.00 61.97 ? 83 ARG I CZ 1 +ATOM 15883 N NH1 . ARG I 1 83 ? 46.766 -14.940 12.816 1.00 77.62 ? 83 ARG I NH1 1 +ATOM 15884 N NH2 . ARG I 1 83 ? 45.037 -14.016 11.574 1.00 51.99 ? 83 ARG I NH2 1 +ATOM 15885 N N . GLN I 1 84 ? 46.256 -21.183 16.665 1.00 86.02 ? 84 GLN I N 1 +ATOM 15886 C CA . GLN I 1 84 ? 46.233 -22.133 17.796 1.00 99.11 ? 84 GLN I CA 1 +ATOM 15887 C C . GLN I 1 84 ? 47.105 -21.626 18.948 1.00 91.34 ? 84 GLN I C 1 +ATOM 15888 O O . GLN I 1 84 ? 46.732 -21.712 20.097 1.00 82.28 ? 84 GLN I O 1 +ATOM 15889 C CB . GLN I 1 84 ? 46.646 -23.557 17.379 1.00 120.13 ? 84 GLN I CB 1 +ATOM 15890 C CG . GLN I 1 84 ? 45.965 -24.667 18.172 1.00 115.80 ? 84 GLN I CG 1 +ATOM 15891 C CD . GLN I 1 84 ? 46.472 -26.052 17.788 1.00 164.39 ? 84 GLN I CD 1 +ATOM 15892 O OE1 . GLN I 1 84 ? 46.759 -26.324 16.620 1.00 220.49 ? 84 GLN I OE1 1 +ATOM 15893 N NE2 . GLN I 1 84 ? 46.555 -26.947 18.768 1.00 176.06 ? 84 GLN I NE2 1 +ATOM 15894 N N . GLY I 1 85 ? 48.269 -21.072 18.646 1.00 100.51 ? 85 GLY I N 1 +ATOM 15895 C CA . GLY I 1 85 ? 49.120 -20.582 19.717 1.00 104.51 ? 85 GLY I CA 1 +ATOM 15896 C C . GLY I 1 85 ? 49.204 -19.074 19.720 1.00 97.23 ? 85 GLY I C 1 +ATOM 15897 O O . GLY I 1 85 ? 50.277 -18.517 19.971 1.00 95.03 ? 85 GLY I O 1 +ATOM 15898 N N . LEU I 1 86 ? 48.081 -18.406 19.456 1.00 87.81 ? 86 LEU I N 1 +ATOM 15899 C CA . LEU I 1 86 ? 48.092 -16.962 19.177 1.00 96.11 ? 86 LEU I CA 1 +ATOM 15900 C C . LEU I 1 86 ? 48.695 -16.162 20.344 1.00 87.68 ? 86 LEU I C 1 +ATOM 15901 O O . LEU I 1 86 ? 49.392 -15.166 20.125 1.00 78.19 ? 86 LEU I O 1 +ATOM 15902 C CB . LEU I 1 86 ? 46.679 -16.446 18.861 1.00 83.38 ? 86 LEU I CB 1 +ATOM 15903 C CG . LEU I 1 86 ? 46.440 -14.943 18.718 1.00 92.09 ? 86 LEU I CG 1 +ATOM 15904 C CD1 . LEU I 1 86 ? 47.258 -14.317 17.598 1.00 117.33 ? 86 LEU I CD1 1 +ATOM 15905 C CD2 . LEU I 1 86 ? 44.959 -14.685 18.486 1.00 84.32 ? 86 LEU I CD2 1 +ATOM 15906 N N . GLN I 1 87 ? 48.491 -16.648 21.562 1.00 81.24 ? 87 GLN I N 1 +ATOM 15907 C CA . GLN I 1 87 ? 48.906 -15.903 22.736 1.00 103.58 ? 87 GLN I CA 1 +ATOM 15908 C C . GLN I 1 87 ? 50.438 -15.746 22.778 1.00 113.05 ? 87 GLN I C 1 +ATOM 15909 O O . GLN I 1 87 ? 50.983 -14.658 23.049 1.00 107.16 ? 87 GLN I O 1 +ATOM 15910 C CB . GLN I 1 87 ? 48.360 -16.579 24.000 1.00 112.91 ? 87 GLN I CB 1 +ATOM 15911 C CG . GLN I 1 87 ? 48.022 -15.603 25.126 1.00 121.49 ? 87 GLN I CG 1 +ATOM 15912 C CD . GLN I 1 87 ? 47.277 -14.346 24.663 1.00 124.64 ? 87 GLN I CD 1 +ATOM 15913 O OE1 . GLN I 1 87 ? 46.220 -14.426 24.028 1.00 121.31 ? 87 GLN I OE1 1 +ATOM 15914 N NE2 . GLN I 1 87 ? 47.842 -13.176 24.961 1.00 120.71 ? 87 GLN I NE2 1 +ATOM 15915 N N . ASN I 1 88 ? 51.135 -16.829 22.452 1.00 96.72 ? 88 ASN I N 1 +ATOM 15916 C CA . ASN I 1 88 ? 52.595 -16.812 22.426 1.00 85.20 ? 88 ASN I CA 1 +ATOM 15917 C C . ASN I 1 88 ? 53.138 -15.884 21.356 1.00 79.43 ? 88 ASN I C 1 +ATOM 15918 O O . ASN I 1 88 ? 54.204 -15.272 21.490 1.00 60.08 ? 88 ASN I O 1 +ATOM 15919 C CB . ASN I 1 88 ? 53.108 -18.213 22.163 1.00 82.39 ? 88 ASN I CB 1 +ATOM 15920 C CG . ASN I 1 88 ? 52.580 -19.196 23.161 1.00 91.72 ? 88 ASN I CG 1 +ATOM 15921 O OD1 . ASN I 1 88 ? 52.497 -18.880 24.354 1.00 61.56 ? 88 ASN I OD1 1 +ATOM 15922 N ND2 . ASN I 1 88 ? 52.278 -20.416 22.705 1.00 106.82 ? 88 ASN I ND2 1 +ATOM 15923 N N . LEU I 1 89 ? 52.428 -15.862 20.242 1.00 87.64 ? 89 LEU I N 1 +ATOM 15924 C CA . LEU I 1 89 ? 52.831 -15.072 19.101 1.00 81.27 ? 89 LEU I CA 1 +ATOM 15925 C C . LEU I 1 89 ? 52.817 -13.608 19.561 1.00 66.17 ? 89 LEU I C 1 +ATOM 15926 O O . LEU I 1 89 ? 53.710 -12.828 19.231 1.00 48.78 ? 89 LEU I O 1 +ATOM 15927 C CB . LEU I 1 89 ? 51.868 -15.374 17.920 1.00 89.77 ? 89 LEU I CB 1 +ATOM 15928 C CG . LEU I 1 89 ? 52.351 -15.253 16.482 1.00 90.26 ? 89 LEU I CG 1 +ATOM 15929 C CD1 . LEU I 1 89 ? 51.613 -14.124 15.791 1.00 101.55 ? 89 LEU I CD1 1 +ATOM 15930 C CD2 . LEU I 1 89 ? 53.849 -14.998 16.424 1.00 122.95 ? 89 LEU I CD2 1 +ATOM 15931 N N . LEU I 1 90 ? 51.769 -13.248 20.300 1.00 79.61 ? 90 LEU I N 1 +ATOM 15932 C CA . LEU I 1 90 ? 51.556 -11.857 20.686 1.00 74.62 ? 90 LEU I CA 1 +ATOM 15933 C C . LEU I 1 90 ? 52.570 -11.482 21.741 1.00 71.34 ? 90 LEU I C 1 +ATOM 15934 O O . LEU I 1 90 ? 53.014 -10.327 21.826 1.00 53.49 ? 90 LEU I O 1 +ATOM 15935 C CB . LEU I 1 90 ? 50.145 -11.674 21.209 1.00 69.73 ? 90 LEU I CB 1 +ATOM 15936 C CG . LEU I 1 90 ? 49.043 -11.973 20.190 1.00 69.78 ? 90 LEU I CG 1 +ATOM 15937 C CD1 . LEU I 1 90 ? 47.737 -12.184 20.923 1.00 90.97 ? 90 LEU I CD1 1 +ATOM 15938 C CD2 . LEU I 1 90 ? 48.939 -10.812 19.218 1.00 80.32 ? 90 LEU I CD2 1 +ATOM 15939 N N . ASN I 1 91 ? 52.974 -12.484 22.518 1.00 70.68 ? 91 ASN I N 1 +ATOM 15940 C CA . ASN I 1 91 ? 54.000 -12.296 23.544 1.00 87.84 ? 91 ASN I CA 1 +ATOM 15941 C C . ASN I 1 91 ? 55.392 -12.036 22.944 1.00 73.30 ? 91 ASN I C 1 +ATOM 15942 O O . ASN I 1 91 ? 56.065 -11.072 23.310 1.00 56.28 ? 91 ASN I O 1 +ATOM 15943 C CB . ASN I 1 91 ? 54.050 -13.538 24.425 1.00 110.52 ? 91 ASN I CB 1 +ATOM 15944 C CG . ASN I 1 91 ? 53.664 -13.301 25.863 1.00 113.95 ? 91 ASN I CG 1 +ATOM 15945 O OD1 . ASN I 1 91 ? 52.965 -12.347 26.208 1.00 88.09 ? 91 ASN I OD1 1 +ATOM 15946 N ND2 . ASN I 1 91 ? 54.090 -14.234 26.709 1.00 117.98 ? 91 ASN I ND2 1 +ATOM 15947 N N . GLU I 1 92 ? 55.800 -12.872 21.991 1.00 74.40 ? 92 GLU I N 1 +ATOM 15948 C CA . GLU I 1 92 ? 57.059 -12.621 21.262 1.00 71.64 ? 92 GLU I CA 1 +ATOM 15949 C C . GLU I 1 92 ? 57.074 -11.234 20.596 1.00 66.80 ? 92 GLU I C 1 +ATOM 15950 O O . GLU I 1 92 ? 58.102 -10.557 20.542 1.00 68.61 ? 92 GLU I O 1 +ATOM 15951 C CB . GLU I 1 92 ? 57.330 -13.702 20.209 1.00 57.42 ? 92 GLU I CB 1 +ATOM 15952 C CG . GLU I 1 92 ? 58.143 -14.881 20.725 1.00 59.25 ? 92 GLU I CG 1 +ATOM 15953 C CD . GLU I 1 92 ? 59.519 -14.491 21.355 1.00 64.58 ? 92 GLU I CD 1 +ATOM 15954 O OE1 . GLU I 1 92 ? 60.336 -13.798 20.752 1.00 57.18 ? 92 GLU I OE1 1 +ATOM 15955 O OE2 . GLU I 1 92 ? 59.780 -14.818 22.499 1.00 45.32 ? 92 GLU I OE2 1 +ATOM 15956 N N . ARG I 1 93 ? 55.910 -10.794 20.134 1.00 76.20 ? 93 ARG I N 1 +ATOM 15957 C CA . ARG I 1 93 ? 55.787 -9.488 19.510 1.00 80.83 ? 93 ARG I CA 1 +ATOM 15958 C C . ARG I 1 93 ? 55.875 -8.361 20.547 1.00 82.95 ? 93 ARG I C 1 +ATOM 15959 O O . ARG I 1 93 ? 56.492 -7.317 20.284 1.00 94.78 ? 93 ARG I O 1 +ATOM 15960 C CB . ARG I 1 93 ? 54.500 -9.422 18.670 1.00 64.74 ? 93 ARG I CB 1 +ATOM 15961 C CG . ARG I 1 93 ? 54.585 -10.318 17.429 1.00 46.11 ? 93 ARG I CG 1 +ATOM 15962 C CD . ARG I 1 93 ? 53.280 -10.553 16.762 1.00 36.97 ? 93 ARG I CD 1 +ATOM 15963 N NE . ARG I 1 93 ? 53.154 -9.688 15.587 1.00 39.37 ? 93 ARG I NE 1 +ATOM 15964 C CZ . ARG I 1 93 ? 52.486 -8.532 15.546 1.00 46.21 ? 93 ARG I CZ 1 +ATOM 15965 N NH1 . ARG I 1 93 ? 51.910 -8.008 16.646 1.00 48.27 ? 93 ARG I NH1 1 +ATOM 15966 N NH2 . ARG I 1 93 ? 52.361 -7.899 14.392 1.00 50.41 ? 93 ARG I NH2 1 +ATOM 15967 N N . LYS I 1 94 ? 55.394 -8.617 21.752 1.00 79.68 ? 94 LYS I N 1 +ATOM 15968 C CA . LYS I 1 94 ? 55.643 -7.684 22.849 1.00 107.81 ? 94 LYS I CA 1 +ATOM 15969 C C . LYS I 1 94 ? 57.143 -7.539 23.129 1.00 99.62 ? 94 LYS I C 1 +ATOM 15970 O O . LYS I 1 94 ? 57.637 -6.432 23.400 1.00 84.21 ? 94 LYS I O 1 +ATOM 15971 C CB . LYS I 1 94 ? 54.941 -8.146 24.127 1.00 126.31 ? 94 LYS I CB 1 +ATOM 15972 C CG . LYS I 1 94 ? 53.497 -7.690 24.265 1.00 149.47 ? 94 LYS I CG 1 +ATOM 15973 C CD . LYS I 1 94 ? 52.843 -8.369 25.460 1.00 146.94 ? 94 LYS I CD 1 +ATOM 15974 C CE . LYS I 1 94 ? 51.602 -7.637 25.954 1.00 138.23 ? 94 LYS I CE 1 +ATOM 15975 N NZ . LYS I 1 94 ? 50.820 -8.514 26.865 1.00 135.99 ? 94 LYS I NZ 1 +ATOM 15976 N N . ILE I 1 95 ? 57.851 -8.668 23.123 1.00 87.01 ? 95 ILE I N 1 +ATOM 15977 C CA . ILE I 1 95 ? 59.259 -8.665 23.506 1.00 75.87 ? 95 ILE I CA 1 +ATOM 15978 C C . ILE I 1 95 ? 60.085 -7.954 22.459 1.00 64.92 ? 95 ILE I C 1 +ATOM 15979 O O . ILE I 1 95 ? 61.052 -7.249 22.785 1.00 61.95 ? 95 ILE I O 1 +ATOM 15980 C CB . ILE I 1 95 ? 59.841 -10.080 23.725 1.00 77.53 ? 95 ILE I CB 1 +ATOM 15981 C CG1 . ILE I 1 95 ? 58.938 -10.912 24.629 1.00 65.22 ? 95 ILE I CG1 1 +ATOM 15982 C CG2 . ILE I 1 95 ? 61.201 -9.942 24.390 1.00 98.67 ? 95 ILE I CG2 1 +ATOM 15983 C CD1 . ILE I 1 95 ? 59.580 -12.167 25.171 1.00 67.09 ? 95 ILE I CD1 1 +ATOM 15984 N N . ILE I 1 96 ? 59.734 -8.222 21.205 1.00 68.65 ? 96 ILE I N 1 +ATOM 15985 C CA . ILE I 1 96 ? 60.322 -7.538 20.076 1.00 79.02 ? 96 ILE I CA 1 +ATOM 15986 C C . ILE I 1 96 ? 60.153 -6.047 20.283 1.00 73.63 ? 96 ILE I C 1 +ATOM 15987 O O . ILE I 1 96 ? 61.139 -5.313 20.277 1.00 103.52 ? 96 ILE I O 1 +ATOM 15988 C CB . ILE I 1 96 ? 59.690 -7.948 18.713 1.00 84.22 ? 96 ILE I CB 1 +ATOM 15989 C CG1 . ILE I 1 96 ? 60.021 -9.405 18.379 1.00 76.55 ? 96 ILE I CG1 1 +ATOM 15990 C CG2 . ILE I 1 96 ? 60.234 -7.071 17.599 1.00 73.17 ? 96 ILE I CG2 1 +ATOM 15991 C CD1 . ILE I 1 96 ? 59.483 -9.849 17.040 1.00 60.46 ? 96 ILE I CD1 1 +ATOM 15992 N N . ARG I 1 97 ? 58.912 -5.593 20.400 1.00 63.77 ? 97 ARG I N 1 +ATOM 15993 C CA . ARG I 1 97 ? 58.635 -4.150 20.441 1.00 76.46 ? 97 ARG I CA 1 +ATOM 15994 C C . ARG I 1 97 ? 59.338 -3.505 21.636 1.00 90.07 ? 97 ARG I C 1 +ATOM 15995 O O . ARG I 1 97 ? 59.723 -2.327 21.589 1.00 81.02 ? 97 ARG I O 1 +ATOM 15996 C CB . ARG I 1 97 ? 57.129 -3.878 20.517 1.00 75.82 ? 97 ARG I CB 1 +ATOM 15997 C CG . ARG I 1 97 ? 56.499 -3.393 19.228 1.00 72.62 ? 97 ARG I CG 1 +ATOM 15998 C CD . ARG I 1 97 ? 55.019 -3.099 19.408 1.00 76.62 ? 97 ARG I CD 1 +ATOM 15999 N NE . ARG I 1 97 ? 54.201 -4.323 19.343 1.00 93.90 ? 97 ARG I NE 1 +ATOM 16000 C CZ . ARG I 1 97 ? 53.527 -4.738 18.265 1.00 109.64 ? 97 ARG I CZ 1 +ATOM 16001 N NH1 . ARG I 1 97 ? 53.567 -4.049 17.115 1.00 96.98 ? 97 ARG I NH1 1 +ATOM 16002 N NH2 . ARG I 1 97 ? 52.807 -5.858 18.331 1.00 120.34 ? 97 ARG I NH2 1 +ATOM 16003 N N . ALA I 1 98 ? 59.510 -4.279 22.704 1.00 80.12 ? 98 ALA I N 1 +ATOM 16004 C CA . ALA I 1 98 ? 60.189 -3.774 23.878 1.00 87.32 ? 98 ALA I CA 1 +ATOM 16005 C C . ALA I 1 98 ? 61.695 -3.705 23.652 1.00 80.89 ? 98 ALA I C 1 +ATOM 16006 O O . ALA I 1 98 ? 62.390 -2.854 24.234 1.00 75.25 ? 98 ALA I O 1 +ATOM 16007 C CB . ALA I 1 98 ? 59.871 -4.654 25.067 1.00 97.77 ? 98 ALA I CB 1 +ATOM 16008 N N . ALA I 1 99 ? 62.178 -4.574 22.772 1.00 75.12 ? 99 ALA I N 1 +ATOM 16009 C CA . ALA I 1 99 ? 63.597 -4.627 22.437 1.00 82.66 ? 99 ALA I CA 1 +ATOM 16010 C C . ALA I 1 99 ? 64.057 -3.413 21.640 1.00 72.57 ? 99 ALA I C 1 +ATOM 16011 O O . ALA I 1 99 ? 65.058 -2.773 21.971 1.00 85.68 ? 99 ALA I O 1 +ATOM 16012 C CB . ALA I 1 99 ? 63.907 -5.897 21.652 1.00 115.61 ? 99 ALA I CB 1 +ATOM 16013 N N . GLN I 1 100 ? 63.326 -3.103 20.585 1.00 64.08 ? 100 GLN I N 1 +ATOM 16014 C CA . GLN I 1 100 ? 63.830 -2.191 19.567 1.00 79.76 ? 100 GLN I CA 1 +ATOM 16015 C C . GLN I 1 100 ? 63.184 -0.818 19.584 1.00 82.54 ? 100 GLN I C 1 +ATOM 16016 O O . GLN I 1 100 ? 63.437 0.004 18.698 1.00 102.23 ? 100 GLN I O 1 +ATOM 16017 C CB . GLN I 1 100 ? 63.686 -2.820 18.171 1.00 100.89 ? 100 GLN I CB 1 +ATOM 16018 C CG . GLN I 1 100 ? 62.367 -3.528 17.905 1.00 108.29 ? 100 GLN I CG 1 +ATOM 16019 C CD . GLN I 1 100 ? 62.485 -4.639 16.866 1.00 102.07 ? 100 GLN I CD 1 +ATOM 16020 O OE1 . GLN I 1 100 ? 63.239 -5.626 17.040 1.00 70.03 ? 100 GLN I OE1 1 +ATOM 16021 N NE2 . GLN I 1 100 ? 61.697 -4.506 15.805 1.00 83.03 ? 100 GLN I NE2 1 +ATOM 16022 N N . GLU I 1 101 ? 62.369 -0.554 20.595 1.00 101.43 ? 101 GLU I N 1 +ATOM 16023 C CA . GLU I 1 101 ? 61.677 0.734 20.691 1.00 117.26 ? 101 GLU I CA 1 +ATOM 16024 C C . GLU I 1 101 ? 62.629 1.913 20.927 1.00 112.53 ? 101 GLU I C 1 +ATOM 16025 O O . GLU I 1 101 ? 62.298 3.055 20.600 1.00 86.94 ? 101 GLU I O 1 +ATOM 16026 C CB . GLU I 1 101 ? 60.597 0.695 21.780 1.00 121.42 ? 101 GLU I CB 1 +ATOM 16027 C CG . GLU I 1 101 ? 61.085 0.218 23.143 1.00 125.33 ? 101 GLU I CG 1 +ATOM 16028 C CD . GLU I 1 101 ? 60.002 0.283 24.208 1.00 114.39 ? 101 GLU I CD 1 +ATOM 16029 O OE1 . GLU I 1 101 ? 58.817 0.359 23.835 1.00 125.04 ? 101 GLU I OE1 1 +ATOM 16030 O OE2 . GLU I 1 101 ? 60.329 0.232 25.416 1.00 103.86 ? 101 GLU I OE2 1 +ATOM 16031 N N . ASN I 1 102 ? 63.807 1.642 21.483 1.00 102.17 ? 102 ASN I N 1 +ATOM 16032 C CA . ASN I 1 102 ? 64.750 2.712 21.791 1.00 112.68 ? 102 ASN I CA 1 +ATOM 16033 C C . ASN I 1 102 ? 65.751 2.996 20.673 1.00 138.92 ? 102 ASN I C 1 +ATOM 16034 O O . ASN I 1 102 ? 66.612 3.859 20.812 1.00 142.72 ? 102 ASN I O 1 +ATOM 16035 C CB . ASN I 1 102 ? 65.487 2.389 23.082 1.00 118.34 ? 102 ASN I CB 1 +ATOM 16036 C CG . ASN I 1 102 ? 64.596 2.514 24.282 1.00 134.01 ? 102 ASN I CG 1 +ATOM 16037 O OD1 . ASN I 1 102 ? 64.325 3.624 24.766 1.00 132.66 ? 102 ASN I OD1 1 +ATOM 16038 N ND2 . ASN I 1 102 ? 64.090 1.372 24.757 1.00 149.44 ? 102 ASN I ND2 1 +ATOM 16039 N N . GLY I 1 103 ? 65.697 2.212 19.602 1.00 147.29 ? 103 GLY I N 1 +ATOM 16040 C CA . GLY I 1 103 ? 66.662 2.353 18.508 1.00 131.66 ? 103 GLY I CA 1 +ATOM 16041 C C . GLY I 1 103 ? 68.123 2.146 18.888 1.00 117.33 ? 103 GLY I C 1 +ATOM 16042 O O . GLY I 1 103 ? 69.017 2.817 18.376 1.00 146.65 ? 103 GLY I O 1 +ATOM 16043 N N . THR I 1 104 ? 68.364 1.248 19.829 1.00 119.63 ? 104 THR I N 1 +ATOM 16044 C CA . THR I 1 104 ? 69.716 0.834 20.139 1.00 130.47 ? 104 THR I CA 1 +ATOM 16045 C C . THR I 1 104 ? 69.979 -0.506 19.502 1.00 120.30 ? 104 THR I C 1 +ATOM 16046 O O . THR I 1 104 ? 71.110 -0.799 19.159 1.00 93.08 ? 104 THR I O 1 +ATOM 16047 C CB . THR I 1 104 ? 69.988 0.751 21.667 1.00 154.20 ? 104 THR I CB 1 +ATOM 16048 O OG1 . THR I 1 104 ? 69.174 -0.260 22.278 1.00 138.33 ? 104 THR I OG1 1 +ATOM 16049 C CG2 . THR I 1 104 ? 69.723 2.108 22.341 1.00 144.45 ? 104 THR I CG2 1 +ATOM 16050 N N . VAL I 1 105 ? 68.930 -1.299 19.291 1.00 158.99 ? 105 VAL I N 1 +ATOM 16051 C CA . VAL I 1 105 ? 69.120 -2.673 18.803 1.00 191.41 ? 105 VAL I CA 1 +ATOM 16052 C C . VAL I 1 105 ? 69.843 -2.673 17.451 1.00 208.22 ? 105 VAL I C 1 +ATOM 16053 O O . VAL I 1 105 ? 69.582 -1.816 16.584 1.00 120.68 ? 105 VAL I O 1 +ATOM 16054 C CB . VAL I 1 105 ? 67.797 -3.503 18.748 1.00 170.21 ? 105 VAL I CB 1 +ATOM 16055 C CG1 . VAL I 1 105 ? 67.794 -4.505 17.593 1.00 140.34 ? 105 VAL I CG1 1 +ATOM 16056 C CG2 . VAL I 1 105 ? 67.570 -4.236 20.067 1.00 135.45 ? 105 VAL I CG2 1 +ATOM 16057 N N . ALA I 1 106 ? 70.758 -3.637 17.309 1.00 216.54 ? 106 ALA I N 1 +ATOM 16058 C CA . ALA I 1 106 ? 71.671 -3.721 16.174 1.00 193.48 ? 106 ALA I CA 1 +ATOM 16059 C C . ALA I 1 106 ? 70.901 -3.911 14.872 1.00 196.94 ? 106 ALA I C 1 +ATOM 16060 O O . ALA I 1 106 ? 69.983 -4.735 14.794 1.00 286.57 ? 106 ALA I O 1 +ATOM 16061 C CB . ALA I 1 106 ? 72.656 -4.865 16.378 1.00 154.55 ? 106 ALA I CB 1 +ATOM 16062 N N . ILE I 1 107 ? 71.268 -3.129 13.861 1.00 156.00 ? 107 ILE I N 1 +ATOM 16063 C CA . ILE I 1 107 ? 70.529 -3.087 12.599 1.00 134.38 ? 107 ILE I CA 1 +ATOM 16064 C C . ILE I 1 107 ? 70.431 -4.472 11.920 1.00 113.36 ? 107 ILE I C 1 +ATOM 16065 O O . ILE I 1 107 ? 69.462 -4.768 11.213 1.00 88.92 ? 107 ILE I O 1 +ATOM 16066 C CB . ILE I 1 107 ? 71.161 -2.041 11.645 1.00 137.21 ? 107 ILE I CB 1 +ATOM 16067 C CG1 . ILE I 1 107 ? 70.240 -1.754 10.452 1.00 144.48 ? 107 ILE I CG1 1 +ATOM 16068 C CG2 . ILE I 1 107 ? 72.537 -2.502 11.165 1.00 144.01 ? 107 ILE I CG2 1 +ATOM 16069 C CD1 . ILE I 1 107 ? 68.848 -1.268 10.819 1.00 117.84 ? 107 ILE I CD1 1 +ATOM 16070 N N . ASN I 1 108 ? 71.446 -5.310 12.124 1.00 137.53 ? 108 ASN I N 1 +ATOM 16071 C CA . ASN I 1 108 ? 71.452 -6.694 11.610 1.00 146.65 ? 108 ASN I CA 1 +ATOM 16072 C C . ASN I 1 108 ? 70.452 -7.561 12.367 1.00 147.10 ? 108 ASN I C 1 +ATOM 16073 O O . ASN I 1 108 ? 69.824 -8.451 11.801 1.00 147.72 ? 108 ASN I O 1 +ATOM 16074 C CB . ASN I 1 108 ? 72.841 -7.327 11.755 1.00 142.47 ? 108 ASN I CB 1 +ATOM 16075 C CG . ASN I 1 108 ? 73.962 -6.307 11.651 1.00 165.78 ? 108 ASN I CG 1 +ATOM 16076 O OD1 . ASN I 1 108 ? 74.421 -5.986 10.558 1.00 170.34 ? 108 ASN I OD1 1 +ATOM 16077 N ND2 . ASN I 1 108 ? 74.395 -5.778 12.797 1.00 161.25 ? 108 ASN I ND2 1 +ATOM 16078 N N . ASN I 1 109 ? 70.307 -7.271 13.655 1.00 141.23 ? 109 ASN I N 1 +ATOM 16079 C CA . ASN I 1 109 ? 69.476 -8.067 14.551 1.00 128.82 ? 109 ASN I CA 1 +ATOM 16080 C C . ASN I 1 109 ? 68.007 -7.637 14.558 1.00 117.25 ? 109 ASN I C 1 +ATOM 16081 O O . ASN I 1 109 ? 67.139 -8.382 15.007 1.00 116.00 ? 109 ASN I O 1 +ATOM 16082 C CB . ASN I 1 109 ? 70.042 -7.991 15.970 1.00 139.99 ? 109 ASN I CB 1 +ATOM 16083 C CG . ASN I 1 109 ? 70.518 -9.337 16.470 1.00 157.49 ? 109 ASN I CG 1 +ATOM 16084 O OD1 . ASN I 1 109 ? 69.953 -9.893 17.406 1.00 162.62 ? 109 ASN I OD1 1 +ATOM 16085 N ND2 . ASN I 1 109 ? 71.539 -9.886 15.820 1.00 179.67 ? 109 ASN I ND2 1 +ATOM 16086 N N . ARG I 1 110 ? 67.745 -6.432 14.049 1.00 97.68 ? 110 ARG I N 1 +ATOM 16087 C CA . ARG I 1 110 ? 66.422 -5.800 14.105 1.00 77.58 ? 110 ARG I CA 1 +ATOM 16088 C C . ARG I 1 110 ? 65.363 -6.692 13.468 1.00 91.53 ? 110 ARG I C 1 +ATOM 16089 O O . ARG I 1 110 ? 65.567 -7.227 12.363 1.00 98.92 ? 110 ARG I O 1 +ATOM 16090 C CB . ARG I 1 110 ? 66.479 -4.453 13.351 1.00 87.44 ? 110 ARG I CB 1 +ATOM 16091 C CG . ARG I 1 110 ? 65.419 -3.440 13.752 1.00 94.52 ? 110 ARG I CG 1 +ATOM 16092 C CD . ARG I 1 110 ? 65.935 -2.006 13.685 1.00 92.54 ? 110 ARG I CD 1 +ATOM 16093 N NE . ARG I 1 110 ? 65.757 -1.389 12.360 1.00 96.74 ? 110 ARG I NE 1 +ATOM 16094 C CZ . ARG I 1 110 ? 65.024 -0.287 12.113 1.00 114.13 ? 110 ARG I CZ 1 +ATOM 16095 N NH1 . ARG I 1 110 ? 64.395 0.362 13.095 1.00 111.01 ? 110 ARG I NH1 1 +ATOM 16096 N NH2 . ARG I 1 110 ? 64.935 0.187 10.876 1.00 102.91 ? 110 ARG I NH2 1 +ATOM 16097 N N . ILE I 1 111 ? 64.214 -6.831 14.128 1.00 105.69 ? 111 ILE I N 1 +ATOM 16098 C CA . ILE I 1 111 ? 63.061 -7.546 13.524 1.00 104.69 ? 111 ILE I CA 1 +ATOM 16099 C C . ILE I 1 111 ? 61.944 -6.583 13.145 1.00 96.09 ? 111 ILE I C 1 +ATOM 16100 O O . ILE I 1 111 ? 61.395 -5.946 14.015 1.00 76.08 ? 111 ILE I O 1 +ATOM 16101 C CB . ILE I 1 111 ? 62.474 -8.599 14.476 1.00 89.10 ? 111 ILE I CB 1 +ATOM 16102 C CG1 . ILE I 1 111 ? 63.543 -9.667 14.750 1.00 121.06 ? 111 ILE I CG1 1 +ATOM 16103 C CG2 . ILE I 1 111 ? 61.234 -9.230 13.865 1.00 70.56 ? 111 ILE I CG2 1 +ATOM 16104 C CD1 . ILE I 1 111 ? 63.214 -10.603 15.890 1.00 134.29 ? 111 ILE I CD1 1 +ATOM 16105 N N . PRO I 1 112 ? 61.624 -6.469 11.842 1.00 98.46 ? 112 PRO I N 1 +ATOM 16106 C CA . PRO I 1 112 ? 60.618 -5.510 11.397 1.00 93.49 ? 112 PRO I CA 1 +ATOM 16107 C C . PRO I 1 112 ? 59.221 -6.077 11.595 1.00 113.59 ? 112 PRO I C 1 +ATOM 16108 O O . PRO I 1 112 ? 58.972 -7.250 11.234 1.00 107.60 ? 112 PRO I O 1 +ATOM 16109 C CB . PRO I 1 112 ? 60.919 -5.358 9.917 1.00 101.74 ? 112 PRO I CB 1 +ATOM 16110 C CG . PRO I 1 112 ? 61.474 -6.693 9.513 1.00 120.73 ? 112 PRO I CG 1 +ATOM 16111 C CD . PRO I 1 112 ? 62.134 -7.293 10.727 1.00 115.96 ? 112 PRO I CD 1 +ATOM 16112 N N . LEU I 1 113 ? 58.352 -5.292 12.244 1.00 129.59 ? 113 LEU I N 1 +ATOM 16113 C CA . LEU I 1 113 ? 57.038 -5.784 12.697 1.00 112.36 ? 113 LEU I CA 1 +ATOM 16114 C C . LEU I 1 113 ? 55.907 -5.189 11.922 1.00 103.45 ? 113 LEU I C 1 +ATOM 16115 O O . LEU I 1 113 ? 55.921 -4.011 11.533 1.00 94.84 ? 113 LEU I O 1 +ATOM 16116 C CB . LEU I 1 113 ? 56.791 -5.500 14.166 1.00 106.14 ? 113 LEU I CB 1 +ATOM 16117 C CG . LEU I 1 113 ? 57.314 -6.561 15.132 1.00 128.57 ? 113 LEU I CG 1 +ATOM 16118 C CD1 . LEU I 1 113 ? 56.897 -6.154 16.524 1.00 123.20 ? 113 LEU I CD1 1 +ATOM 16119 C CD2 . LEU I 1 113 ? 56.821 -7.968 14.820 1.00 113.49 ? 113 LEU I CD2 1 +ATOM 16120 N N . GLN I 1 114 ? 54.973 -6.070 11.608 1.00 92.87 ? 114 GLN I N 1 +ATOM 16121 C CA . GLN I 1 114 ? 53.989 -5.819 10.574 1.00 96.94 ? 114 GLN I CA 1 +ATOM 16122 C C . GLN I 1 114 ? 52.766 -6.417 11.166 1.00 83.38 ? 114 GLN I C 1 +ATOM 16123 O O . GLN I 1 114 ? 52.851 -7.380 11.932 1.00 80.19 ? 114 GLN I O 1 +ATOM 16124 C CB . GLN I 1 114 ? 54.346 -6.514 9.239 1.00 105.56 ? 114 GLN I CB 1 +ATOM 16125 C CG . GLN I 1 114 ? 53.860 -5.795 7.957 1.00 94.07 ? 114 GLN I CG 1 +ATOM 16126 C CD . GLN I 1 114 ? 53.811 -6.719 6.678 1.00 111.92 ? 114 GLN I CD 1 +ATOM 16127 O OE1 . GLN I 1 114 ? 53.221 -6.406 5.602 1.00 66.32 ? 114 GLN I OE1 1 +ATOM 16128 N NE2 . GLN I 1 114 ? 54.476 -7.855 6.798 1.00 111.24 ? 114 GLN I NE2 1 +ATOM 16129 N N . SER I 1 115 ? 51.634 -5.796 10.868 1.00 80.14 ? 115 SER I N 1 +ATOM 16130 C CA . SER I 1 115 ? 50.381 -6.180 11.484 1.00 87.32 ? 115 SER I CA 1 +ATOM 16131 C C . SER I 1 115 ? 50.121 -7.645 11.202 1.00 82.10 ? 115 SER I C 1 +ATOM 16132 O O . SER I 1 115 ? 50.647 -8.189 10.194 1.00 85.26 ? 115 SER I O 1 +ATOM 16133 C CB . SER I 1 115 ? 49.241 -5.319 10.935 1.00 107.94 ? 115 SER I CB 1 +ATOM 16134 O OG . SER I 1 115 ? 49.225 -5.319 9.493 1.00 86.28 ? 115 SER I OG 1 +ATOM 16135 N N . LEU I 1 116 ? 49.346 -8.303 12.074 1.00 63.62 ? 116 LEU I N 1 +ATOM 16136 C CA . LEU I 1 116 ? 49.226 -9.743 11.930 1.00 73.35 ? 116 LEU I CA 1 +ATOM 16137 C C . LEU I 1 116 ? 48.377 -10.039 10.691 1.00 92.95 ? 116 LEU I C 1 +ATOM 16138 O O . LEU I 1 116 ? 47.319 -9.447 10.531 1.00 82.72 ? 116 LEU I O 1 +ATOM 16139 C CB . LEU I 1 116 ? 48.590 -10.383 13.127 1.00 60.59 ? 116 LEU I CB 1 +ATOM 16140 C CG . LEU I 1 116 ? 49.385 -10.317 14.404 1.00 55.58 ? 116 LEU I CG 1 +ATOM 16141 C CD1 . LEU I 1 116 ? 48.936 -9.087 15.231 1.00 66.20 ? 116 LEU I CD1 1 +ATOM 16142 C CD2 . LEU I 1 116 ? 49.182 -11.607 15.181 1.00 42.62 ? 116 LEU I CD2 1 +ATOM 16143 N N . THR I 1 117 ? 48.923 -10.835 9.761 1.00 112.32 ? 117 THR I N 1 +ATOM 16144 C CA . THR I 1 117 ? 48.254 -11.153 8.489 1.00 88.75 ? 117 THR I CA 1 +ATOM 16145 C C . THR I 1 117 ? 46.939 -11.778 8.812 1.00 87.63 ? 117 THR I C 1 +ATOM 16146 O O . THR I 1 117 ? 46.864 -12.593 9.735 1.00 82.29 ? 117 THR I O 1 +ATOM 16147 C CB . THR I 1 117 ? 49.032 -12.178 7.665 1.00 81.76 ? 117 THR I CB 1 +ATOM 16148 O OG1 . THR I 1 117 ? 50.368 -11.716 7.452 1.00 108.60 ? 117 THR I OG1 1 +ATOM 16149 C CG2 . THR I 1 117 ? 48.360 -12.393 6.330 1.00 85.67 ? 117 THR I CG2 1 +ATOM 16150 N N . ALA I 1 118 ? 45.893 -11.309 8.142 1.00 93.01 ? 118 ALA I N 1 +ATOM 16151 C CA . ALA I 1 118 ? 44.535 -11.610 8.567 1.00 110.50 ? 118 ALA I CA 1 +ATOM 16152 C C . ALA I 1 118 ? 43.839 -12.442 7.526 1.00 101.02 ? 118 ALA I C 1 +ATOM 16153 O O . ALA I 1 118 ? 43.908 -12.141 6.333 1.00 82.63 ? 118 ALA I O 1 +ATOM 16154 C CB . ALA I 1 118 ? 43.737 -10.336 8.839 1.00 119.43 ? 118 ALA I CB 1 +ATOM 16155 N N . ALA I 1 119 ? 43.050 -13.394 8.016 1.00 86.45 ? 119 ALA I N 1 +ATOM 16156 C CA . ALA I 1 119 ? 42.369 -14.372 7.170 1.00 78.34 ? 119 ALA I CA 1 +ATOM 16157 C C . ALA I 1 119 ? 41.043 -13.880 6.665 1.00 71.63 ? 119 ALA I C 1 +ATOM 16158 O O . ALA I 1 119 ? 40.391 -13.030 7.317 1.00 68.30 ? 119 ALA I O 1 +ATOM 16159 C CB . ALA I 1 119 ? 42.168 -15.650 7.951 1.00 87.54 ? 119 ALA I CB 1 +ATOM 16160 N N . ASN I 1 120 ? 40.594 -14.435 5.542 1.00 95.79 ? 120 ASN I N 1 +ATOM 16161 C CA . ASN I 1 120 ? 39.238 -14.113 5.057 1.00 137.73 ? 120 ASN I CA 1 +ATOM 16162 C C . ASN I 1 120 ? 38.192 -15.174 5.407 1.00 98.79 ? 120 ASN I C 1 +ATOM 16163 O O . ASN I 1 120 ? 37.081 -14.862 5.822 1.00 77.08 ? 120 ASN I O 1 +ATOM 16164 C CB . ASN I 1 120 ? 39.200 -13.875 3.549 1.00 145.57 ? 120 ASN I CB 1 +ATOM 16165 C CG . ASN I 1 120 ? 37.814 -13.426 3.071 1.00 141.23 ? 120 ASN I CG 1 +ATOM 16166 O OD1 . ASN I 1 120 ? 37.346 -13.897 2.034 1.00 171.85 ? 120 ASN I OD1 1 +ATOM 16167 N ND2 . ASN I 1 120 ? 37.123 -12.562 3.856 1.00 105.44 ? 120 ASN I ND2 1 +ATOM 16168 N N . ILE I 1 121 ? 38.546 -16.421 5.192 1.00 69.22 ? 121 ILE I N 1 +ATOM 16169 C CA . ILE I 1 121 ? 37.689 -17.488 5.609 1.00 54.93 ? 121 ILE I CA 1 +ATOM 16170 C C . ILE I 1 121 ? 38.407 -18.151 6.735 1.00 52.46 ? 121 ILE I C 1 +ATOM 16171 O O . ILE I 1 121 ? 39.628 -18.308 6.727 1.00 70.08 ? 121 ILE I O 1 +ATOM 16172 C CB . ILE I 1 121 ? 37.360 -18.484 4.453 1.00 63.63 ? 121 ILE I CB 1 +ATOM 16173 C CG1 . ILE I 1 121 ? 38.562 -19.357 4.056 1.00 56.88 ? 121 ILE I CG1 1 +ATOM 16174 C CG2 . ILE I 1 121 ? 36.832 -17.731 3.232 1.00 71.48 ? 121 ILE I CG2 1 +ATOM 16175 C CD1 . ILE I 1 121 ? 38.397 -20.797 4.432 1.00 55.41 ? 121 ILE I CD1 1 +ATOM 16176 N N . MET I 1 122 ? 37.654 -18.594 7.705 1.00 51.86 ? 122 MET I N 1 +ATOM 16177 C CA . MET I 1 122 ? 38.225 -19.487 8.697 1.00 58.20 ? 122 MET I CA 1 +ATOM 16178 C C . MET I 1 122 ? 37.396 -20.769 8.744 1.00 49.31 ? 122 MET I C 1 +ATOM 16179 O O . MET I 1 122 ? 36.198 -20.777 8.462 1.00 46.48 ? 122 MET I O 1 +ATOM 16180 C CB . MET I 1 122 ? 38.313 -18.809 10.066 1.00 67.24 ? 122 MET I CB 1 +ATOM 16181 C CG . MET I 1 122 ? 36.992 -18.282 10.615 1.00 89.36 ? 122 MET I CG 1 +ATOM 16182 S SD . MET I 1 122 ? 37.049 -18.175 12.406 1.00 70.90 ? 122 MET I SD 1 +ATOM 16183 C CE . MET I 1 122 ? 35.410 -18.889 12.799 1.00 124.29 ? 122 MET I CE 1 +ATOM 16184 N N . VAL I 1 123 ? 38.070 -21.877 8.971 1.00 51.10 ? 123 VAL I N 1 +ATOM 16185 C CA . VAL I 1 123 ? 37.425 -23.176 8.892 1.00 62.85 ? 123 VAL I CA 1 +ATOM 16186 C C . VAL I 1 123 ? 37.568 -23.821 10.226 1.00 61.91 ? 123 VAL I C 1 +ATOM 16187 O O . VAL I 1 123 ? 38.681 -23.994 10.726 1.00 48.05 ? 123 VAL I O 1 +ATOM 16188 C CB . VAL I 1 123 ? 38.016 -24.130 7.788 1.00 73.00 ? 123 VAL I CB 1 +ATOM 16189 C CG1 . VAL I 1 123 ? 39.526 -24.013 7.691 1.00 78.79 ? 123 VAL I CG1 1 +ATOM 16190 C CG2 . VAL I 1 123 ? 37.597 -25.583 8.037 1.00 83.46 ? 123 VAL I CG2 1 +ATOM 16191 N N . GLU I 1 124 ? 36.443 -24.241 10.784 1.00 83.60 ? 124 GLU I N 1 +ATOM 16192 C CA . GLU I 1 124 ? 36.475 -25.042 12.011 1.00 98.39 ? 124 GLU I CA 1 +ATOM 16193 C C . GLU I 1 124 ? 35.698 -26.312 11.826 1.00 61.26 ? 124 GLU I C 1 +ATOM 16194 O O . GLU I 1 124 ? 34.929 -26.442 10.884 1.00 75.04 ? 124 GLU I O 1 +ATOM 16195 C CB . GLU I 1 124 ? 35.954 -24.233 13.212 1.00 115.66 ? 124 GLU I CB 1 +ATOM 16196 C CG . GLU I 1 124 ? 34.927 -23.158 12.886 1.00 102.33 ? 124 GLU I CG 1 +ATOM 16197 C CD . GLU I 1 124 ? 34.797 -22.171 14.021 1.00 98.14 ? 124 GLU I CD 1 +ATOM 16198 O OE1 . GLU I 1 124 ? 35.831 -21.816 14.648 1.00 144.66 ? 124 GLU I OE1 1 +ATOM 16199 O OE2 . GLU I 1 124 ? 33.689 -21.681 14.249 1.00 93.09 ? 124 GLU I OE2 1 +ATOM 16200 N N . GLY I 1 125 ? 35.792 -27.173 12.813 1.00 42.22 ? 125 GLY I N 1 +ATOM 16201 C CA . GLY I 1 125 ? 35.105 -28.428 12.752 1.00 40.46 ? 125 GLY I CA 1 +ATOM 16202 C C . GLY I 1 125 ? 35.170 -29.178 14.046 1.00 44.95 ? 125 GLY I C 1 +ATOM 16203 O O . GLY I 1 125 ? 35.497 -28.614 15.114 1.00 55.47 ? 125 GLY I O 1 +ATOM 16204 N N . SER I 1 126 ? 34.976 -30.485 13.967 1.00 47.71 ? 126 SER I N 1 +ATOM 16205 C CA . SER I 1 126 ? 34.946 -31.281 15.188 1.00 63.82 ? 126 SER I CA 1 +ATOM 16206 C C . SER I 1 126 ? 35.165 -32.716 14.813 1.00 62.46 ? 126 SER I C 1 +ATOM 16207 O O . SER I 1 126 ? 34.670 -33.156 13.779 1.00 57.45 ? 126 SER I O 1 +ATOM 16208 C CB . SER I 1 126 ? 33.587 -31.113 15.921 1.00 83.14 ? 126 SER I CB 1 +ATOM 16209 O OG . SER I 1 126 ? 32.999 -29.817 15.742 1.00 70.28 ? 126 SER I OG 1 +ATOM 16210 N N . ILE I 1 127 ? 35.789 -33.475 15.697 1.00 63.54 ? 127 ILE I N 1 +ATOM 16211 C CA . ILE I 1 127 ? 35.646 -34.911 15.625 1.00 92.72 ? 127 ILE I CA 1 +ATOM 16212 C C . ILE I 1 127 ? 34.258 -35.319 16.156 1.00 106.44 ? 127 ILE I C 1 +ATOM 16213 O O . ILE I 1 127 ? 34.040 -35.397 17.353 1.00 160.33 ? 127 ILE I O 1 +ATOM 16214 C CB . ILE I 1 127 ? 36.757 -35.652 16.384 1.00 84.75 ? 127 ILE I CB 1 +ATOM 16215 C CG1 . ILE I 1 127 ? 38.105 -35.328 15.735 1.00 85.43 ? 127 ILE I CG1 1 +ATOM 16216 C CG2 . ILE I 1 127 ? 36.500 -37.174 16.381 1.00 71.71 ? 127 ILE I CG2 1 +ATOM 16217 C CD1 . ILE I 1 127 ? 39.264 -35.345 16.714 1.00 103.74 ? 127 ILE I CD1 1 +ATOM 16218 N N . ILE I 1 128 ? 33.334 -35.594 15.234 1.00 88.69 ? 128 ILE I N 1 +ATOM 16219 C CA . ILE I 1 128 ? 31.958 -36.046 15.547 1.00 63.24 ? 128 ILE I CA 1 +ATOM 16220 C C . ILE I 1 128 ? 31.959 -37.564 15.578 1.00 74.50 ? 128 ILE I C 1 +ATOM 16221 O O . ILE I 1 128 ? 32.121 -38.244 14.537 1.00 124.00 ? 128 ILE I O 1 +ATOM 16222 C CB . ILE I 1 128 ? 30.969 -35.501 14.522 1.00 45.95 ? 128 ILE I CB 1 +ATOM 16223 C CG1 . ILE I 1 128 ? 31.411 -35.837 13.098 1.00 48.63 ? 128 ILE I CG1 1 +ATOM 16224 C CG2 . ILE I 1 128 ? 30.990 -33.985 14.561 1.00 49.39 ? 128 ILE I CG2 1 +ATOM 16225 C CD1 . ILE I 1 128 ? 30.269 -35.829 12.103 1.00 49.18 ? 128 ILE I CD1 1 +ATOM 16226 N N . GLY I 1 129 ? 32.122 -38.092 16.781 1.00 71.33 ? 129 GLY I N 1 +ATOM 16227 C CA . GLY I 1 129 ? 31.938 -39.504 16.981 1.00 81.89 ? 129 GLY I CA 1 +ATOM 16228 C C . GLY I 1 129 ? 33.179 -40.379 16.823 1.00 80.19 ? 129 GLY I C 1 +ATOM 16229 O O . GLY I 1 129 ? 33.865 -40.365 15.771 1.00 79.50 ? 129 GLY I O 1 +ATOM 16230 N N . TYR I 1 130 ? 33.271 -41.337 17.743 1.00 77.64 ? 130 TYR I N 1 +ATOM 16231 C CA . TYR I 1 130 ? 33.997 -42.574 17.499 1.00 93.43 ? 130 TYR I CA 1 +ATOM 16232 C C . TYR I 1 130 ? 33.166 -43.691 18.090 1.00 104.03 ? 130 TYR I C 1 +ATOM 16233 O O . TYR I 1 130 ? 32.994 -43.766 19.293 1.00 92.73 ? 130 TYR I O 1 +ATOM 16234 C CB . TYR I 1 130 ? 35.345 -42.478 18.186 1.00 112.14 ? 130 TYR I CB 1 +ATOM 16235 C CG . TYR I 1 130 ? 36.217 -43.734 18.166 1.00 112.45 ? 130 TYR I CG 1 +ATOM 16236 C CD1 . TYR I 1 130 ? 35.962 -44.805 19.028 1.00 109.68 ? 130 TYR I CD1 1 +ATOM 16237 C CD2 . TYR I 1 130 ? 37.371 -43.778 17.390 1.00 96.53 ? 130 TYR I CD2 1 +ATOM 16238 C CE1 . TYR I 1 130 ? 36.764 -45.932 19.035 1.00 81.98 ? 130 TYR I CE1 1 +ATOM 16239 C CE2 . TYR I 1 130 ? 38.183 -44.891 17.399 1.00 89.88 ? 130 TYR I CE2 1 +ATOM 16240 C CZ . TYR I 1 130 ? 37.854 -45.971 18.198 1.00 84.52 ? 130 TYR I CZ 1 +ATOM 16241 O OH . TYR I 1 130 ? 38.683 -47.051 18.186 1.00 134.11 ? 130 TYR I OH 1 +ATOM 16242 N N . GLU I 1 131 ? 32.586 -44.532 17.238 1.00 118.73 ? 131 GLU I N 1 +ATOM 16243 C CA . GLU I 1 131 ? 31.923 -45.742 17.717 1.00 118.51 ? 131 GLU I CA 1 +ATOM 16244 C C . GLU I 1 131 ? 32.880 -46.915 17.590 1.00 88.67 ? 131 GLU I C 1 +ATOM 16245 O O . GLU I 1 131 ? 33.734 -46.930 16.695 1.00 62.70 ? 131 GLU I O 1 +ATOM 16246 C CB . GLU I 1 131 ? 30.652 -45.984 16.917 1.00 158.31 ? 131 GLU I CB 1 +ATOM 16247 C CG . GLU I 1 131 ? 29.743 -47.078 17.452 1.00 173.11 ? 131 GLU I CG 1 +ATOM 16248 C CD . GLU I 1 131 ? 28.757 -46.593 18.507 1.00 159.61 ? 131 GLU I CD 1 +ATOM 16249 O OE1 . GLU I 1 131 ? 28.379 -45.388 18.481 1.00 147.56 ? 131 GLU I OE1 1 +ATOM 16250 O OE2 . GLU I 1 131 ? 28.338 -47.434 19.340 1.00 136.64 ? 131 GLU I OE2 1 +ATOM 16251 N N . SER I 1 132 ? 32.801 -47.855 18.531 1.00 80.03 ? 132 SER I N 1 +ATOM 16252 C CA . SER I 1 132 ? 33.802 -48.927 18.614 1.00 87.04 ? 132 SER I CA 1 +ATOM 16253 C C . SER I 1 132 ? 33.209 -50.321 18.413 1.00 88.63 ? 132 SER I C 1 +ATOM 16254 O O . SER I 1 132 ? 32.101 -50.605 18.889 1.00 99.80 ? 132 SER I O 1 +ATOM 16255 C CB . SER I 1 132 ? 34.523 -48.861 19.952 1.00 78.45 ? 132 SER I CB 1 +ATOM 16256 O OG . SER I 1 132 ? 34.216 -49.987 20.754 1.00 75.01 ? 132 SER I OG 1 +ATOM 16257 N N . ASN I 1 133 ? 33.951 -51.181 17.718 1.00 75.43 ? 133 ASN I N 1 +ATOM 16258 C CA . ASN I 1 133 ? 33.416 -52.457 17.258 1.00 91.30 ? 133 ASN I CA 1 +ATOM 16259 C C . ASN I 1 133 ? 32.050 -52.282 16.622 1.00 103.18 ? 133 ASN I C 1 +ATOM 16260 O O . ASN I 1 133 ? 31.069 -52.940 17.000 1.00 105.29 ? 133 ASN I O 1 +ATOM 16261 C CB . ASN I 1 133 ? 33.318 -53.463 18.396 1.00 94.52 ? 133 ASN I CB 1 +ATOM 16262 C CG . ASN I 1 133 ? 34.662 -53.712 19.046 1.00 120.73 ? 133 ASN I CG 1 +ATOM 16263 O OD1 . ASN I 1 133 ? 35.717 -53.679 18.389 1.00 89.94 ? 133 ASN I OD1 1 +ATOM 16264 N ND2 . ASN I 1 133 ? 34.633 -54.022 20.331 1.00 153.13 ? 133 ASN I ND2 1 +ATOM 16265 N N . VAL I 1 134 ? 32.017 -51.440 15.597 1.00 109.92 ? 134 VAL I N 1 +ATOM 16266 C CA . VAL I 1 134 ? 30.807 -51.210 14.816 1.00 115.09 ? 134 VAL I CA 1 +ATOM 16267 C C . VAL I 1 134 ? 30.474 -52.497 14.048 1.00 126.55 ? 134 VAL I C 1 +ATOM 16268 O O . VAL I 1 134 ? 29.304 -52.863 13.898 1.00 122.50 ? 134 VAL I O 1 +ATOM 16269 C CB . VAL I 1 134 ? 30.997 -50.028 13.842 1.00 108.03 ? 134 VAL I CB 1 +ATOM 16270 C CG1 . VAL I 1 134 ? 29.718 -49.713 13.101 1.00 109.49 ? 134 VAL I CG1 1 +ATOM 16271 C CG2 . VAL I 1 134 ? 31.475 -48.797 14.602 1.00 116.19 ? 134 VAL I CG2 1 +ATOM 16272 N N . LYS I 1 135 ? 31.515 -53.211 13.620 1.00 138.32 ? 135 LYS I N 1 +ATOM 16273 C CA . LYS I 1 135 ? 31.368 -54.605 13.197 1.00 128.09 ? 135 LYS I CA 1 +ATOM 16274 C C . LYS I 1 135 ? 32.484 -55.473 13.748 1.00 117.78 ? 135 LYS I C 1 +ATOM 16275 O O . LYS I 1 135 ? 33.572 -54.983 14.109 1.00 109.33 ? 135 LYS I O 1 +ATOM 16276 C CB . LYS I 1 135 ? 31.370 -54.709 11.677 1.00 127.51 ? 135 LYS I CB 1 +ATOM 16277 C CG . LYS I 1 135 ? 30.211 -53.982 11.019 1.00 125.14 ? 135 LYS I CG 1 +ATOM 16278 C CD . LYS I 1 135 ? 30.346 -54.034 9.510 1.00 119.00 ? 135 LYS I CD 1 +ATOM 16279 C CE . LYS I 1 135 ? 29.215 -53.313 8.818 1.00 120.42 ? 135 LYS I CE 1 +ATOM 16280 N NZ . LYS I 1 135 ? 29.086 -53.779 7.413 1.00 102.01 ? 135 LYS I NZ 1 +ATOM 16281 N N . SER I 1 136 ? 32.218 -56.772 13.788 1.00 117.02 ? 136 SER I N 1 +ATOM 16282 C CA . SER I 1 136 ? 33.203 -57.733 14.264 1.00 124.73 ? 136 SER I CA 1 +ATOM 16283 C C . SER I 1 136 ? 32.853 -59.145 13.833 1.00 137.59 ? 136 SER I C 1 +ATOM 16284 O O . SER I 1 136 ? 31.689 -59.447 13.564 1.00 183.26 ? 136 SER I O 1 +ATOM 16285 C CB . SER I 1 136 ? 33.339 -57.656 15.786 1.00 108.11 ? 136 SER I CB 1 +ATOM 16286 O OG . SER I 1 136 ? 33.132 -58.923 16.395 1.00 113.78 ? 136 SER I OG 1 +ATOM 16287 N N . GLY I 1 137 ? 33.864 -60.006 13.768 1.00 120.74 ? 137 GLY I N 1 +ATOM 16288 C CA . GLY I 1 137 ? 33.636 -61.399 13.411 1.00 144.85 ? 137 GLY I CA 1 +ATOM 16289 C C . GLY I 1 137 ? 34.829 -62.294 13.652 1.00 163.80 ? 137 GLY I C 1 +ATOM 16290 O O . GLY I 1 137 ? 35.881 -61.840 14.095 1.00 167.73 ? 137 GLY I O 1 +ATOM 16291 N N . GLY I 1 138 ? 34.641 -63.593 13.432 1.00 206.37 ? 138 GLY I N 1 +ATOM 16292 C CA . GLY I 1 138 ? 35.706 -64.566 13.664 1.00 211.07 ? 138 GLY I CA 1 +ATOM 16293 C C . GLY I 1 138 ? 35.414 -65.921 13.052 1.00 201.84 ? 138 GLY I C 1 +ATOM 16294 O O . GLY I 1 138 ? 34.260 -66.360 13.016 1.00 226.26 ? 138 GLY I O 1 +ATOM 16295 N N . VAL I 1 139 ? 36.470 -66.585 12.586 1.00 160.66 ? 139 VAL I N 1 +ATOM 16296 C CA . VAL I 1 139 ? 36.363 -67.933 12.047 1.00 143.67 ? 139 VAL I CA 1 +ATOM 16297 C C . VAL I 1 139 ? 37.547 -68.768 12.502 1.00 146.77 ? 139 VAL I C 1 +ATOM 16298 O O . VAL I 1 139 ? 38.706 -68.386 12.297 1.00 174.07 ? 139 VAL I O 1 +ATOM 16299 C CB . VAL I 1 139 ? 36.334 -67.933 10.513 1.00 135.43 ? 139 VAL I CB 1 +ATOM 16300 C CG1 . VAL I 1 139 ? 36.350 -69.357 9.993 1.00 125.10 ? 139 VAL I CG1 1 +ATOM 16301 C CG2 . VAL I 1 139 ? 35.107 -67.190 9.996 1.00 161.73 ? 139 VAL I CG2 1 +ATOM 16302 N N . GLY I 1 140 ? 37.253 -69.917 13.105 1.00 155.12 ? 140 GLY I N 1 +ATOM 16303 C CA . GLY I 1 140 ? 38.295 -70.794 13.634 1.00 165.99 ? 140 GLY I CA 1 +ATOM 16304 C C . GLY I 1 140 ? 37.927 -72.267 13.637 1.00 157.98 ? 140 GLY I C 1 +ATOM 16305 O O . GLY I 1 140 ? 36.777 -72.636 13.871 1.00 165.77 ? 140 GLY I O 1 +ATOM 16306 N N . ALA I 1 141 ? 38.921 -73.112 13.396 1.00 158.55 ? 141 ALA I N 1 +ATOM 16307 C CA . ALA I 1 141 ? 38.720 -74.553 13.403 1.00 164.73 ? 141 ALA I CA 1 +ATOM 16308 C C . ALA I 1 141 ? 39.939 -75.295 13.945 1.00 187.05 ? 141 ALA I C 1 +ATOM 16309 O O . ALA I 1 141 ? 41.087 -74.916 13.698 1.00 200.29 ? 141 ALA I O 1 +ATOM 16310 C CB . ALA I 1 141 ? 38.381 -75.041 12.006 1.00 149.50 ? 141 ALA I CB 1 +ATOM 16311 N N . ARG I 1 142 ? 39.678 -76.338 14.716 1.00 203.58 ? 142 ARG I N 1 +ATOM 16312 C CA . ARG I 1 142 ? 40.733 -77.240 15.127 1.00 207.87 ? 142 ARG I CA 1 +ATOM 16313 C C . ARG I 1 142 ? 40.317 -78.660 14.796 1.00 202.61 ? 142 ARG I C 1 +ATOM 16314 O O . ARG I 1 142 ? 39.136 -79.001 14.879 1.00 164.31 ? 142 ARG I O 1 +ATOM 16315 C CB . ARG I 1 142 ? 41.052 -77.093 16.621 1.00 219.31 ? 142 ARG I CB 1 +ATOM 16316 C CG . ARG I 1 142 ? 42.224 -77.961 17.072 1.00 213.21 ? 142 ARG I CG 1 +ATOM 16317 C CD . ARG I 1 142 ? 43.145 -77.237 18.028 1.00 199.51 ? 142 ARG I CD 1 +ATOM 16318 N NE . ARG I 1 142 ? 42.545 -77.225 19.358 1.00 195.44 ? 142 ARG I NE 1 +ATOM 16319 C CZ . ARG I 1 142 ? 42.769 -76.292 20.277 1.00 179.98 ? 142 ARG I CZ 1 +ATOM 16320 N NH1 . ARG I 1 142 ? 43.661 -75.327 20.065 1.00 181.22 ? 142 ARG I NH1 1 +ATOM 16321 N NH2 . ARG I 1 142 ? 42.137 -76.354 21.442 1.00 156.22 ? 142 ARG I NH2 1 +ATOM 16322 N N . TYR I 1 143 ? 41.296 -79.473 14.405 1.00 218.56 ? 143 TYR I N 1 +ATOM 16323 C CA . TYR I 1 143 ? 41.039 -80.824 13.911 1.00 199.61 ? 143 TYR I CA 1 +ATOM 16324 C C . TYR I 1 143 ? 41.949 -81.859 14.582 1.00 183.50 ? 143 TYR I C 1 +ATOM 16325 O O . TYR I 1 143 ? 43.018 -82.210 14.065 1.00 162.20 ? 143 TYR I O 1 +ATOM 16326 C CB . TYR I 1 143 ? 41.228 -80.848 12.395 1.00 200.65 ? 143 TYR I CB 1 +ATOM 16327 C CG . TYR I 1 143 ? 40.824 -82.135 11.746 1.00 206.87 ? 143 TYR I CG 1 +ATOM 16328 C CD1 . TYR I 1 143 ? 39.478 -82.483 11.626 1.00 189.20 ? 143 TYR I CD1 1 +ATOM 16329 C CD2 . TYR I 1 143 ? 41.777 -82.987 11.220 1.00 214.23 ? 143 TYR I CD2 1 +ATOM 16330 C CE1 . TYR I 1 143 ? 39.082 -83.655 11.016 1.00 158.36 ? 143 TYR I CE1 1 +ATOM 16331 C CE2 . TYR I 1 143 ? 41.390 -84.162 10.599 1.00 211.30 ? 143 TYR I CE2 1 +ATOM 16332 C CZ . TYR I 1 143 ? 40.044 -84.491 10.504 1.00 179.51 ? 143 TYR I CZ 1 +ATOM 16333 O OH . TYR I 1 143 ? 39.667 -85.660 9.892 1.00 169.96 ? 143 TYR I OH 1 +ATOM 16334 N N . GLY I 1 145 ? 44.192 -82.136 16.147 1.00 119.90 ? 145 GLY I N 1 +ATOM 16335 C CA . GLY I 1 145 ? 45.482 -81.661 16.619 1.00 126.61 ? 145 GLY I CA 1 +ATOM 16336 C C . GLY I 1 145 ? 45.915 -80.297 16.092 1.00 137.89 ? 145 GLY I C 1 +ATOM 16337 O O . GLY I 1 145 ? 46.721 -79.619 16.739 1.00 153.59 ? 145 GLY I O 1 +ATOM 16338 N N . ILE I 1 146 ? 45.446 -79.921 14.904 1.00 146.63 ? 146 ILE I N 1 +ATOM 16339 C CA . ILE I 1 146 ? 45.941 -78.726 14.205 1.00 157.51 ? 146 ILE I CA 1 +ATOM 16340 C C . ILE I 1 146 ? 44.808 -77.702 14.152 1.00 193.37 ? 146 ILE I C 1 +ATOM 16341 O O . ILE I 1 146 ? 43.662 -78.060 13.885 1.00 247.98 ? 146 ILE I O 1 +ATOM 16342 C CB . ILE I 1 146 ? 46.427 -79.047 12.761 1.00 129.07 ? 146 ILE I CB 1 +ATOM 16343 C CG1 . ILE I 1 146 ? 47.186 -80.381 12.728 1.00 110.96 ? 146 ILE I CG1 1 +ATOM 16344 C CG2 . ILE I 1 146 ? 47.306 -77.924 12.217 1.00 97.26 ? 146 ILE I CG2 1 +ATOM 16345 C CD1 . ILE I 1 146 ? 46.336 -81.566 12.316 1.00 101.81 ? 146 ILE I CD1 1 +ATOM 16346 N N . GLY I 1 147 ? 45.111 -76.432 14.404 1.00 185.33 ? 147 GLY I N 1 +ATOM 16347 C CA . GLY I 1 147 ? 44.062 -75.414 14.435 1.00 169.54 ? 147 GLY I CA 1 +ATOM 16348 C C . GLY I 1 147 ? 44.480 -74.020 14.018 1.00 167.62 ? 147 GLY I C 1 +ATOM 16349 O O . GLY I 1 147 ? 45.642 -73.645 14.124 1.00 180.52 ? 147 GLY I O 1 +ATOM 16350 N N . ALA I 1 148 ? 43.509 -73.244 13.555 1.00 166.07 ? 148 ALA I N 1 +ATOM 16351 C CA . ALA I 1 148 ? 43.730 -71.840 13.256 1.00 144.56 ? 148 ALA I CA 1 +ATOM 16352 C C . ALA I 1 148 ? 42.456 -71.033 13.516 1.00 138.53 ? 148 ALA I C 1 +ATOM 16353 O O . ALA I 1 148 ? 41.374 -71.593 13.714 1.00 138.62 ? 148 ALA I O 1 +ATOM 16354 C CB . ALA I 1 148 ? 44.211 -71.669 11.818 1.00 112.43 ? 148 ALA I CB 1 +ATOM 16355 N N . ASP I 1 149 ? 42.608 -69.714 13.541 1.00 142.02 ? 149 ASP I N 1 +ATOM 16356 C CA . ASP I 1 149 ? 41.495 -68.803 13.761 1.00 156.91 ? 149 ASP I CA 1 +ATOM 16357 C C . ASP I 1 149 ? 41.866 -67.398 13.350 1.00 161.17 ? 149 ASP I C 1 +ATOM 16358 O O . ASP I 1 149 ? 43.006 -66.997 13.528 1.00 128.19 ? 149 ASP I O 1 +ATOM 16359 C CB . ASP I 1 149 ? 41.154 -68.841 15.269 1.00 145.31 ? 149 ASP I CB 1 +ATOM 16360 C CG . ASP I 1 149 ? 40.233 -67.714 15.748 1.00 154.53 ? 149 ASP I CG 1 +ATOM 16361 O OD1 . ASP I 1 149 ? 40.742 -66.584 15.920 1.00 154.22 ? 149 ASP I OD1 1 +ATOM 16362 O OD2 . ASP I 1 149 ? 39.071 -68.004 16.161 1.00 159.29 ? 149 ASP I OD2 1 +ATOM 16363 N N . THR I 1 150 ? 40.927 -66.669 12.750 1.00 165.25 ? 150 THR I N 1 +ATOM 16364 C CA . THR I 1 150 ? 41.071 -65.220 12.673 1.00 145.30 ? 150 THR I CA 1 +ATOM 16365 C C . THR I 1 150 ? 39.898 -64.574 13.394 1.00 150.84 ? 150 THR I C 1 +ATOM 16366 O O . THR I 1 150 ? 38.818 -65.160 13.487 1.00 137.13 ? 150 THR I O 1 +ATOM 16367 C CB . THR I 1 150 ? 41.170 -64.688 11.224 1.00 117.71 ? 150 THR I CB 1 +ATOM 16368 O OG1 . THR I 1 150 ? 40.001 -65.077 10.495 1.00 161.77 ? 150 THR I OG1 1 +ATOM 16369 C CG2 . THR I 1 150 ? 42.406 -65.226 10.531 1.00 110.31 ? 150 THR I CG2 1 +ATOM 16370 N N . GLN I 1 151 ? 40.133 -63.382 13.923 1.00 144.93 ? 151 GLN I N 1 +ATOM 16371 C CA . GLN I 1 151 ? 39.045 -62.554 14.444 1.00 130.93 ? 151 GLN I CA 1 +ATOM 16372 C C . GLN I 1 151 ? 39.297 -61.091 14.018 1.00 146.44 ? 151 GLN I C 1 +ATOM 16373 O O . GLN I 1 151 ? 40.438 -60.675 13.789 1.00 182.32 ? 151 GLN I O 1 +ATOM 16374 C CB . GLN I 1 151 ? 38.823 -62.742 15.960 1.00 101.86 ? 151 GLN I CB 1 +ATOM 16375 C CG . GLN I 1 151 ? 39.922 -62.164 16.815 1.00 125.15 ? 151 GLN I CG 1 +ATOM 16376 C CD . GLN I 1 151 ? 39.513 -61.973 18.265 1.00 143.12 ? 151 GLN I CD 1 +ATOM 16377 O OE1 . GLN I 1 151 ? 38.762 -62.776 18.813 1.00 152.91 ? 151 GLN I OE1 1 +ATOM 16378 N NE2 . GLN I 1 151 ? 39.960 -60.869 18.879 1.00 156.15 ? 151 GLN I NE2 1 +ATOM 16379 N N . TYR I 1 152 ? 38.228 -60.371 13.714 1.00 139.12 ? 152 TYR I N 1 +ATOM 16380 C CA . TYR I 1 152 ? 38.375 -58.999 13.254 1.00 117.45 ? 152 TYR I CA 1 +ATOM 16381 C C . TYR I 1 152 ? 37.380 -58.108 13.936 1.00 117.46 ? 152 TYR I C 1 +ATOM 16382 O O . TYR I 1 152 ? 36.253 -58.531 14.233 1.00 113.84 ? 152 TYR I O 1 +ATOM 16383 C CB . TYR I 1 152 ? 38.266 -58.903 11.728 1.00 110.82 ? 152 TYR I CB 1 +ATOM 16384 C CG . TYR I 1 152 ? 36.965 -58.369 11.175 1.00 106.60 ? 152 TYR I CG 1 +ATOM 16385 C CD1 . TYR I 1 152 ? 35.751 -59.070 11.325 1.00 98.94 ? 152 TYR I CD1 1 +ATOM 16386 C CD2 . TYR I 1 152 ? 36.961 -57.227 10.395 1.00 95.09 ? 152 TYR I CD2 1 +ATOM 16387 C CE1 . TYR I 1 152 ? 34.563 -58.593 10.772 1.00 88.40 ? 152 TYR I CE1 1 +ATOM 16388 C CE2 . TYR I 1 152 ? 35.786 -56.768 9.796 1.00 108.91 ? 152 TYR I CE2 1 +ATOM 16389 C CZ . TYR I 1 152 ? 34.591 -57.458 9.979 1.00 96.96 ? 152 TYR I CZ 1 +ATOM 16390 O OH . TYR I 1 152 ? 33.446 -56.979 9.393 1.00 74.11 ? 152 TYR I OH 1 +ATOM 16391 N N . GLN I 1 153 ? 37.796 -56.872 14.196 1.00 110.24 ? 153 GLN I N 1 +ATOM 16392 C CA . GLN I 1 153 ? 36.861 -55.840 14.628 1.00 116.78 ? 153 GLN I CA 1 +ATOM 16393 C C . GLN I 1 153 ? 37.103 -54.531 13.870 1.00 107.91 ? 153 GLN I C 1 +ATOM 16394 O O . GLN I 1 153 ? 38.197 -54.309 13.339 1.00 107.35 ? 153 GLN I O 1 +ATOM 16395 C CB . GLN I 1 153 ? 37.014 -55.609 16.120 1.00 117.93 ? 153 GLN I CB 1 +ATOM 16396 C CG . GLN I 1 153 ? 36.635 -56.801 17.003 1.00 129.65 ? 153 GLN I CG 1 +ATOM 16397 C CD . GLN I 1 153 ? 36.960 -56.535 18.481 1.00 147.97 ? 153 GLN I CD 1 +ATOM 16398 O OE1 . GLN I 1 153 ? 37.756 -55.646 18.809 1.00 153.05 ? 153 GLN I OE1 1 +ATOM 16399 N NE2 . GLN I 1 153 ? 36.317 -57.278 19.375 1.00 163.73 ? 153 GLN I NE2 1 +ATOM 16400 N N . LEU I 1 154 ? 36.055 -53.718 13.727 1.00 90.30 ? 154 LEU I N 1 +ATOM 16401 C CA . LEU I 1 154 ? 36.235 -52.405 13.117 1.00 84.31 ? 154 LEU I CA 1 +ATOM 16402 C C . LEU I 1 154 ? 35.386 -51.331 13.766 1.00 89.86 ? 154 LEU I C 1 +ATOM 16403 O O . LEU I 1 154 ? 34.228 -51.565 14.153 1.00 86.67 ? 154 LEU I O 1 +ATOM 16404 C CB . LEU I 1 154 ? 35.988 -52.445 11.612 1.00 77.36 ? 154 LEU I CB 1 +ATOM 16405 C CG . LEU I 1 154 ? 34.540 -52.630 11.187 1.00 97.80 ? 154 LEU I CG 1 +ATOM 16406 C CD1 . LEU I 1 154 ? 33.878 -51.295 10.892 1.00 111.82 ? 154 LEU I CD1 1 +ATOM 16407 C CD2 . LEU I 1 154 ? 34.471 -53.544 9.973 1.00 123.79 ? 154 LEU I CD2 1 +ATOM 16408 N N . ASP I 1 155 ? 35.965 -50.130 13.784 1.00 109.64 ? 155 ASP I N 1 +ATOM 16409 C CA . ASP I 1 155 ? 35.463 -48.966 14.525 1.00 98.25 ? 155 ASP I CA 1 +ATOM 16410 C C . ASP I 1 155 ? 35.245 -47.809 13.536 1.00 101.00 ? 155 ASP I C 1 +ATOM 16411 O O . ASP I 1 155 ? 35.737 -47.846 12.408 1.00 77.20 ? 155 ASP I O 1 +ATOM 16412 C CB . ASP I 1 155 ? 36.483 -48.517 15.570 1.00 98.71 ? 155 ASP I CB 1 +ATOM 16413 C CG . ASP I 1 155 ? 37.036 -49.675 16.380 1.00 134.05 ? 155 ASP I CG 1 +ATOM 16414 O OD1 . ASP I 1 155 ? 37.924 -50.397 15.866 1.00 187.06 ? 155 ASP I OD1 1 +ATOM 16415 O OD2 . ASP I 1 155 ? 36.563 -49.887 17.508 1.00 126.35 ? 155 ASP I OD2 1 +ATOM 16416 N N . GLN I 1 156 ? 34.454 -46.816 13.935 1.00 97.00 ? 156 GLN I N 1 +ATOM 16417 C CA . GLN I 1 156 ? 34.136 -45.706 13.034 1.00 78.95 ? 156 GLN I CA 1 +ATOM 16418 C C . GLN I 1 156 ? 34.665 -44.406 13.600 1.00 61.02 ? 156 GLN I C 1 +ATOM 16419 O O . GLN I 1 156 ? 34.816 -44.269 14.823 1.00 52.22 ? 156 GLN I O 1 +ATOM 16420 C CB . GLN I 1 156 ? 32.617 -45.625 12.794 1.00 96.91 ? 156 GLN I CB 1 +ATOM 16421 C CG . GLN I 1 156 ? 32.225 -44.683 11.670 1.00 101.91 ? 156 GLN I CG 1 +ATOM 16422 C CD . GLN I 1 156 ? 30.881 -45.023 11.054 1.00 90.70 ? 156 GLN I CD 1 +ATOM 16423 O OE1 . GLN I 1 156 ? 30.097 -45.803 11.620 1.00 88.87 ? 156 GLN I OE1 1 +ATOM 16424 N NE2 . GLN I 1 156 ? 30.558 -44.353 9.942 1.00 70.97 ? 156 GLN I NE2 1 +ATOM 16425 N N . ILE I 1 157 ? 34.934 -43.458 12.719 1.00 45.90 ? 157 ILE I N 1 +ATOM 16426 C CA . ILE I 1 157 ? 35.300 -42.133 13.142 1.00 63.14 ? 157 ILE I CA 1 +ATOM 16427 C C . ILE I 1 157 ? 34.803 -41.126 12.113 1.00 71.43 ? 157 ILE I C 1 +ATOM 16428 O O . ILE I 1 157 ? 34.810 -41.385 10.916 1.00 56.68 ? 157 ILE I O 1 +ATOM 16429 C CB . ILE I 1 157 ? 36.830 -42.037 13.294 1.00 84.87 ? 157 ILE I CB 1 +ATOM 16430 C CG1 . ILE I 1 157 ? 37.222 -40.908 14.266 1.00 117.20 ? 157 ILE I CG1 1 +ATOM 16431 C CG2 . ILE I 1 157 ? 37.497 -41.825 11.952 1.00 76.39 ? 157 ILE I CG2 1 +ATOM 16432 C CD1 . ILE I 1 157 ? 38.700 -40.886 14.626 1.00 128.57 ? 157 ILE I CD1 1 +ATOM 16433 N N . ALA I 1 158 ? 34.290 -39.989 12.574 1.00 87.06 ? 158 ALA I N 1 +ATOM 16434 C CA . ALA I 1 158 ? 33.720 -39.015 11.639 1.00 77.79 ? 158 ALA I CA 1 +ATOM 16435 C C . ALA I 1 158 ? 34.207 -37.636 11.978 1.00 61.13 ? 158 ALA I C 1 +ATOM 16436 O O . ALA I 1 158 ? 34.516 -37.348 13.150 1.00 78.29 ? 158 ALA I O 1 +ATOM 16437 C CB . ALA I 1 158 ? 32.197 -39.079 11.642 1.00 77.06 ? 158 ALA I CB 1 +ATOM 16438 N N . VAL I 1 159 ? 34.268 -36.795 10.961 1.00 42.63 ? 159 VAL I N 1 +ATOM 16439 C CA . VAL I 1 159 ? 34.828 -35.489 11.115 1.00 48.17 ? 159 VAL I CA 1 +ATOM 16440 C C . VAL I 1 159 ? 34.034 -34.461 10.366 1.00 60.95 ? 159 VAL I C 1 +ATOM 16441 O O . VAL I 1 159 ? 33.685 -34.647 9.203 1.00 74.29 ? 159 VAL I O 1 +ATOM 16442 C CB . VAL I 1 159 ? 36.276 -35.443 10.624 1.00 52.61 ? 159 VAL I CB 1 +ATOM 16443 C CG1 . VAL I 1 159 ? 36.716 -34.022 10.315 1.00 54.31 ? 159 VAL I CG1 1 +ATOM 16444 C CG2 . VAL I 1 159 ? 37.200 -36.044 11.689 1.00 70.23 ? 159 VAL I CG2 1 +ATOM 16445 N N . ASN I 1 160 ? 33.677 -33.390 11.077 1.00 79.11 ? 160 ASN I N 1 +ATOM 16446 C CA . ASN I 1 160 ? 33.033 -32.236 10.461 1.00 83.79 ? 160 ASN I CA 1 +ATOM 16447 C C . ASN I 1 160 ? 34.117 -31.204 10.212 1.00 67.63 ? 160 ASN I C 1 +ATOM 16448 O O . ASN I 1 160 ? 34.902 -30.900 11.115 1.00 46.19 ? 160 ASN I O 1 +ATOM 16449 C CB . ASN I 1 160 ? 31.938 -31.678 11.390 1.00 89.46 ? 160 ASN I CB 1 +ATOM 16450 C CG . ASN I 1 160 ? 31.279 -30.405 10.852 1.00 106.03 ? 160 ASN I CG 1 +ATOM 16451 O OD1 . ASN I 1 160 ? 31.947 -29.461 10.443 1.00 115.83 ? 160 ASN I OD1 1 +ATOM 16452 N ND2 . ASN I 1 160 ? 29.958 -30.352 10.925 1.00 122.70 ? 160 ASN I ND2 1 +ATOM 16453 N N . LEU I 1 161 ? 34.167 -30.700 8.980 1.00 49.78 ? 161 LEU I N 1 +ATOM 16454 C CA . LEU I 1 161 ? 34.848 -29.454 8.710 1.00 52.76 ? 161 LEU I CA 1 +ATOM 16455 C C . LEU I 1 161 ? 33.901 -28.466 8.057 1.00 46.26 ? 161 LEU I C 1 +ATOM 16456 O O . LEU I 1 161 ? 33.018 -28.830 7.322 1.00 42.41 ? 161 LEU I O 1 +ATOM 16457 C CB . LEU I 1 161 ? 36.038 -29.695 7.799 1.00 61.84 ? 161 LEU I CB 1 +ATOM 16458 C CG . LEU I 1 161 ? 37.146 -30.565 8.370 1.00 66.55 ? 161 LEU I CG 1 +ATOM 16459 C CD1 . LEU I 1 161 ? 38.155 -30.882 7.280 1.00 75.03 ? 161 LEU I CD1 1 +ATOM 16460 C CD2 . LEU I 1 161 ? 37.807 -29.851 9.543 1.00 60.93 ? 161 LEU I CD2 1 +ATOM 16461 N N . ARG I 1 162 ? 34.093 -27.193 8.319 1.00 60.47 ? 162 ARG I N 1 +ATOM 16462 C CA . ARG I 1 162 ? 33.208 -26.200 7.748 1.00 74.44 ? 162 ARG I CA 1 +ATOM 16463 C C . ARG I 1 162 ? 33.849 -24.815 7.588 1.00 74.50 ? 162 ARG I C 1 +ATOM 16464 O O . ARG I 1 162 ? 34.470 -24.276 8.506 1.00 70.28 ? 162 ARG I O 1 +ATOM 16465 C CB . ARG I 1 162 ? 31.892 -26.121 8.540 1.00 92.42 ? 162 ARG I CB 1 +ATOM 16466 C CG . ARG I 1 162 ? 31.981 -25.657 9.989 1.00 118.46 ? 162 ARG I CG 1 +ATOM 16467 C CD . ARG I 1 162 ? 30.600 -25.240 10.491 1.00 124.69 ? 162 ARG I CD 1 +ATOM 16468 N NE . ARG I 1 162 ? 30.624 -24.612 11.813 1.00 128.52 ? 162 ARG I NE 1 +ATOM 16469 C CZ . ARG I 1 162 ? 30.696 -25.275 12.972 1.00 126.87 ? 162 ARG I CZ 1 +ATOM 16470 N NH1 . ARG I 1 162 ? 30.815 -26.603 13.006 1.00 82.38 ? 162 ARG I NH1 1 +ATOM 16471 N NH2 . ARG I 1 162 ? 30.693 -24.588 14.110 1.00 154.29 ? 162 ARG I NH2 1 +ATOM 16472 N N . VAL I 1 163 ? 33.682 -24.268 6.390 1.00 85.56 ? 163 VAL I N 1 +ATOM 16473 C CA . VAL I 1 163 ? 34.178 -22.934 6.042 1.00 96.75 ? 163 VAL I CA 1 +ATOM 16474 C C . VAL I 1 163 ? 33.191 -21.864 6.451 1.00 88.27 ? 163 VAL I C 1 +ATOM 16475 O O . VAL I 1 163 ? 32.045 -21.873 6.003 1.00 121.16 ? 163 VAL I O 1 +ATOM 16476 C CB . VAL I 1 163 ? 34.358 -22.764 4.522 1.00 112.13 ? 163 VAL I CB 1 +ATOM 16477 C CG1 . VAL I 1 163 ? 34.857 -21.345 4.207 1.00 95.12 ? 163 VAL I CG1 1 +ATOM 16478 C CG2 . VAL I 1 163 ? 35.281 -23.854 3.971 1.00 130.80 ? 163 VAL I CG2 1 +ATOM 16479 N N . VAL I 1 164 ? 33.667 -20.933 7.264 1.00 72.76 ? 164 VAL I N 1 +ATOM 16480 C CA . VAL I 1 164 ? 32.859 -19.831 7.741 1.00 47.69 ? 164 VAL I CA 1 +ATOM 16481 C C . VAL I 1 164 ? 33.391 -18.583 7.180 1.00 38.03 ? 164 VAL I C 1 +ATOM 16482 O O . VAL I 1 164 ? 34.619 -18.357 7.174 1.00 54.26 ? 164 VAL I O 1 +ATOM 16483 C CB . VAL I 1 164 ? 32.943 -19.723 9.255 1.00 44.28 ? 164 VAL I CB 1 +ATOM 16484 C CG1 . VAL I 1 164 ? 32.148 -18.535 9.723 1.00 40.70 ? 164 VAL I CG1 1 +ATOM 16485 C CG2 . VAL I 1 164 ? 32.426 -21.004 9.906 1.00 50.19 ? 164 VAL I CG2 1 +ATOM 16486 N N . ASN I 1 165 ? 32.498 -17.769 6.698 1.00 39.97 ? 165 ASN I N 1 +ATOM 16487 C CA . ASN I 1 165 ? 32.902 -16.479 6.168 1.00 73.83 ? 165 ASN I CA 1 +ATOM 16488 C C . ASN I 1 165 ? 33.059 -15.430 7.270 1.00 71.61 ? 165 ASN I C 1 +ATOM 16489 O O . ASN I 1 165 ? 32.085 -15.089 7.933 1.00 94.01 ? 165 ASN I O 1 +ATOM 16490 C CB . ASN I 1 165 ? 31.894 -15.963 5.136 1.00 102.07 ? 165 ASN I CB 1 +ATOM 16491 C CG . ASN I 1 165 ? 32.355 -14.690 4.468 1.00 100.55 ? 165 ASN I CG 1 +ATOM 16492 O OD1 . ASN I 1 165 ? 33.562 -14.371 4.475 1.00 157.59 ? 165 ASN I OD1 1 +ATOM 16493 N ND2 . ASN I 1 165 ? 31.444 -14.040 3.772 1.00 99.75 ? 165 ASN I ND2 1 +ATOM 16494 N N . VAL I 1 166 ? 34.269 -14.885 7.408 1.00 72.87 ? 166 VAL I N 1 +ATOM 16495 C CA . VAL I 1 166 ? 34.589 -13.934 8.454 1.00 60.59 ? 166 VAL I CA 1 +ATOM 16496 C C . VAL I 1 166 ? 33.750 -12.700 8.272 1.00 65.60 ? 166 VAL I C 1 +ATOM 16497 O O . VAL I 1 166 ? 33.257 -12.148 9.268 1.00 121.10 ? 166 VAL I O 1 +ATOM 16498 C CB . VAL I 1 166 ? 36.070 -13.550 8.422 1.00 61.69 ? 166 VAL I CB 1 +ATOM 16499 C CG1 . VAL I 1 166 ? 36.310 -12.169 9.028 1.00 74.02 ? 166 VAL I CG1 1 +ATOM 16500 C CG2 . VAL I 1 166 ? 36.919 -14.629 9.102 1.00 49.24 ? 166 VAL I CG2 1 +ATOM 16501 N N . SER I 1 167 ? 33.529 -12.298 7.020 1.00 58.04 ? 167 SER I N 1 +ATOM 16502 C CA . SER I 1 167 ? 32.866 -11.041 6.741 1.00 65.84 ? 167 SER I CA 1 +ATOM 16503 C C . SER I 1 167 ? 31.355 -11.060 7.024 1.00 87.77 ? 167 SER I C 1 +ATOM 16504 O O . SER I 1 167 ? 30.729 -9.990 7.147 1.00 100.99 ? 167 SER I O 1 +ATOM 16505 C CB . SER I 1 167 ? 33.091 -10.672 5.296 1.00 72.14 ? 167 SER I CB 1 +ATOM 16506 O OG . SER I 1 167 ? 34.447 -10.850 4.944 1.00 72.54 ? 167 SER I OG 1 +ATOM 16507 N N . THR I 1 168 ? 30.771 -12.253 7.201 1.00 96.29 ? 168 THR I N 1 +ATOM 16508 C CA . THR I 1 168 ? 29.319 -12.366 7.517 1.00 75.38 ? 168 THR I CA 1 +ATOM 16509 C C . THR I 1 168 ? 28.913 -13.358 8.639 1.00 61.88 ? 168 THR I C 1 +ATOM 16510 O O . THR I 1 168 ? 27.955 -13.153 9.401 1.00 43.15 ? 168 THR I O 1 +ATOM 16511 C CB . THR I 1 168 ? 28.581 -12.814 6.276 1.00 77.28 ? 168 THR I CB 1 +ATOM 16512 O OG1 . THR I 1 168 ? 29.220 -13.979 5.775 1.00 45.57 ? 168 THR I OG1 1 +ATOM 16513 C CG2 . THR I 1 168 ? 28.590 -11.698 5.247 1.00 97.36 ? 168 THR I CG2 1 +ATOM 16514 N N . GLY I 1 169 ? 29.685 -14.415 8.786 1.00 59.83 ? 169 GLY I N 1 +ATOM 16515 C CA . GLY I 1 169 ? 29.338 -15.440 9.744 1.00 55.67 ? 169 GLY I CA 1 +ATOM 16516 C C . GLY I 1 169 ? 28.588 -16.537 9.026 1.00 53.88 ? 169 GLY I C 1 +ATOM 16517 O O . GLY I 1 169 ? 28.329 -17.587 9.632 1.00 52.57 ? 169 GLY I O 1 +ATOM 16518 N N . GLU I 1 170 ? 28.189 -16.288 7.760 1.00 42.53 ? 170 GLU I N 1 +ATOM 16519 C CA . GLU I 1 170 ? 27.583 -17.339 6.939 1.00 40.16 ? 170 GLU I CA 1 +ATOM 16520 C C . GLU I 1 170 ? 28.575 -18.466 6.971 1.00 34.53 ? 170 GLU I C 1 +ATOM 16521 O O . GLU I 1 170 ? 29.725 -18.274 6.640 1.00 43.46 ? 170 GLU I O 1 +ATOM 16522 C CB . GLU I 1 170 ? 27.309 -16.856 5.518 1.00 45.63 ? 170 GLU I CB 1 +ATOM 16523 C CG . GLU I 1 170 ? 26.065 -15.989 5.390 1.00 84.32 ? 170 GLU I CG 1 +ATOM 16524 C CD . GLU I 1 170 ? 26.180 -14.826 4.395 1.00 115.27 ? 170 GLU I CD 1 +ATOM 16525 O OE1 . GLU I 1 170 ? 27.289 -14.547 3.923 1.00 84.20 ? 170 GLU I OE1 1 +ATOM 16526 O OE2 . GLU I 1 170 ? 25.144 -14.174 4.086 1.00 162.60 ? 170 GLU I OE2 1 +ATOM 16527 N N . ILE I 1 171 ? 28.143 -19.648 7.355 1.00 35.65 ? 171 ILE I N 1 +ATOM 16528 C CA . ILE I 1 171 ? 28.848 -20.828 6.941 1.00 47.37 ? 171 ILE I CA 1 +ATOM 16529 C C . ILE I 1 171 ? 28.799 -21.024 5.398 1.00 70.04 ? 171 ILE I C 1 +ATOM 16530 O O . ILE I 1 171 ? 27.720 -21.052 4.800 1.00 59.96 ? 171 ILE I O 1 +ATOM 16531 C CB . ILE I 1 171 ? 28.288 -22.080 7.622 1.00 37.73 ? 171 ILE I CB 1 +ATOM 16532 C CG1 . ILE I 1 171 ? 28.583 -21.974 9.106 1.00 30.97 ? 171 ILE I CG1 1 +ATOM 16533 C CG2 . ILE I 1 171 ? 28.905 -23.341 6.992 1.00 33.02 ? 171 ILE I CG2 1 +ATOM 16534 C CD1 . ILE I 1 171 ? 27.781 -22.941 9.928 1.00 26.30 ? 171 ILE I CD1 1 +ATOM 16535 N N . LEU I 1 172 ? 29.973 -21.101 4.746 1.00 80.34 ? 172 LEU I N 1 +ATOM 16536 C CA . LEU I 1 172 ? 30.031 -21.186 3.281 1.00 76.14 ? 172 LEU I CA 1 +ATOM 16537 C C . LEU I 1 172 ? 30.079 -22.646 2.784 1.00 87.73 ? 172 LEU I C 1 +ATOM 16538 O O . LEU I 1 172 ? 29.890 -22.944 1.569 1.00 70.23 ? 172 LEU I O 1 +ATOM 16539 C CB . LEU I 1 172 ? 31.212 -20.397 2.721 1.00 79.74 ? 172 LEU I CB 1 +ATOM 16540 C CG . LEU I 1 172 ? 31.093 -18.852 2.843 1.00 95.73 ? 172 LEU I CG 1 +ATOM 16541 C CD1 . LEU I 1 172 ? 32.171 -17.996 2.160 1.00 98.05 ? 172 LEU I CD1 1 +ATOM 16542 C CD2 . LEU I 1 172 ? 29.707 -18.360 2.450 1.00 108.85 ? 172 LEU I CD2 1 +ATOM 16543 N N . SER I 1 173 ? 30.322 -23.561 3.730 1.00 68.72 ? 173 SER I N 1 +ATOM 16544 C CA . SER I 1 173 ? 30.408 -24.979 3.415 1.00 59.03 ? 173 SER I CA 1 +ATOM 16545 C C . SER I 1 173 ? 30.510 -25.807 4.675 1.00 58.50 ? 173 SER I C 1 +ATOM 16546 O O . SER I 1 173 ? 31.349 -25.563 5.515 1.00 81.64 ? 173 SER I O 1 +ATOM 16547 C CB . SER I 1 173 ? 31.637 -25.261 2.525 1.00 60.09 ? 173 SER I CB 1 +ATOM 16548 O OG . SER I 1 173 ? 31.906 -26.648 2.477 1.00 69.94 ? 173 SER I OG 1 +ATOM 16549 N N . SER I 1 174 ? 29.718 -26.858 4.752 1.00 77.60 ? 174 SER I N 1 +ATOM 16550 C CA . SER I 1 174 ? 29.893 -27.881 5.785 1.00 73.89 ? 174 SER I CA 1 +ATOM 16551 C C . SER I 1 174 ? 30.056 -29.218 5.098 1.00 88.57 ? 174 SER I C 1 +ATOM 16552 O O . SER I 1 174 ? 29.321 -29.550 4.156 1.00 105.94 ? 174 SER I O 1 +ATOM 16553 C CB . SER I 1 174 ? 28.674 -27.937 6.740 1.00 81.11 ? 174 SER I CB 1 +ATOM 16554 O OG . SER I 1 174 ? 28.900 -28.749 7.879 1.00 42.69 ? 174 SER I OG 1 +ATOM 16555 N N . VAL I 1 175 ? 30.994 -30.011 5.603 1.00 100.38 ? 175 VAL I N 1 +ATOM 16556 C CA . VAL I 1 175 ? 31.221 -31.372 5.092 1.00 86.58 ? 175 VAL I CA 1 +ATOM 16557 C C . VAL I 1 175 ? 31.409 -32.385 6.214 1.00 61.46 ? 175 VAL I C 1 +ATOM 16558 O O . VAL I 1 175 ? 32.022 -32.070 7.250 1.00 57.02 ? 175 VAL I O 1 +ATOM 16559 C CB . VAL I 1 175 ? 32.442 -31.406 4.155 1.00 105.07 ? 175 VAL I CB 1 +ATOM 16560 C CG1 . VAL I 1 175 ? 32.200 -30.530 2.936 1.00 132.87 ? 175 VAL I CG1 1 +ATOM 16561 C CG2 . VAL I 1 175 ? 33.697 -30.932 4.864 1.00 117.00 ? 175 VAL I CG2 1 +ATOM 16562 N N . ASN I 1 176 ? 30.909 -33.590 5.987 1.00 56.04 ? 176 ASN I N 1 +ATOM 16563 C CA . ASN I 1 176 ? 30.920 -34.644 7.003 1.00 74.36 ? 176 ASN I CA 1 +ATOM 16564 C C . ASN I 1 176 ? 31.583 -35.951 6.554 1.00 75.51 ? 176 ASN I C 1 +ATOM 16565 O O . ASN I 1 176 ? 30.923 -36.775 5.951 1.00 88.51 ? 176 ASN I O 1 +ATOM 16566 C CB . ASN I 1 176 ? 29.474 -34.914 7.423 1.00 81.78 ? 176 ASN I CB 1 +ATOM 16567 C CG . ASN I 1 176 ? 29.108 -34.181 8.728 1.00 96.34 ? 176 ASN I CG 1 +ATOM 16568 O OD1 . ASN I 1 176 ? 29.800 -33.224 9.071 1.00 61.32 ? 176 ASN I OD1 1 +ATOM 16569 N ND2 . ASN I 1 176 ? 27.980 -34.551 9.400 1.00 99.11 ? 176 ASN I ND2 1 +ATOM 16570 N N . THR I 1 177 ? 32.874 -36.137 6.858 1.00 61.44 ? 177 THR I N 1 +ATOM 16571 C CA . THR I 1 177 ? 33.622 -37.298 6.368 1.00 50.30 ? 177 THR I CA 1 +ATOM 16572 C C . THR I 1 177 ? 33.704 -38.365 7.446 1.00 55.89 ? 177 THR I C 1 +ATOM 16573 O O . THR I 1 177 ? 33.476 -38.095 8.627 1.00 45.75 ? 177 THR I O 1 +ATOM 16574 C CB . THR I 1 177 ? 35.050 -36.933 5.936 1.00 49.79 ? 177 THR I CB 1 +ATOM 16575 O OG1 . THR I 1 177 ? 35.838 -36.581 7.079 1.00 54.48 ? 177 THR I OG1 1 +ATOM 16576 C CG2 . THR I 1 177 ? 35.067 -35.769 4.954 1.00 48.66 ? 177 THR I CG2 1 +ATOM 16577 N N . SER I 1 178 ? 33.980 -39.590 7.022 1.00 66.13 ? 178 SER I N 1 +ATOM 16578 C CA . SER I 1 178 ? 33.963 -40.743 7.921 1.00 68.58 ? 178 SER I CA 1 +ATOM 16579 C C . SER I 1 178 ? 34.992 -41.745 7.489 1.00 76.26 ? 178 SER I C 1 +ATOM 16580 O O . SER I 1 178 ? 35.307 -41.880 6.295 1.00 106.02 ? 178 SER I O 1 +ATOM 16581 C CB . SER I 1 178 ? 32.574 -41.412 7.952 1.00 67.08 ? 178 SER I CB 1 +ATOM 16582 O OG . SER I 1 178 ? 32.619 -42.701 8.560 1.00 42.73 ? 178 SER I OG 1 +ATOM 16583 N N . LYS I 1 179 ? 35.464 -42.521 8.446 1.00 73.93 ? 179 LYS I N 1 +ATOM 16584 C CA . LYS I 1 179 ? 36.514 -43.481 8.153 1.00 92.88 ? 179 LYS I CA 1 +ATOM 16585 C C . LYS I 1 179 ? 36.504 -44.654 9.147 1.00 88.00 ? 179 LYS I C 1 +ATOM 16586 O O . LYS I 1 179 ? 36.123 -44.500 10.315 1.00 65.63 ? 179 LYS I O 1 +ATOM 16587 C CB . LYS I 1 179 ? 37.842 -42.755 8.198 1.00 102.48 ? 179 LYS I CB 1 +ATOM 16588 C CG . LYS I 1 179 ? 38.861 -43.236 7.189 1.00 117.32 ? 179 LYS I CG 1 +ATOM 16589 C CD . LYS I 1 179 ? 39.768 -44.284 7.816 1.00 145.52 ? 179 LYS I CD 1 +ATOM 16590 C CE . LYS I 1 179 ? 40.688 -44.883 6.775 1.00 159.20 ? 179 LYS I CE 1 +ATOM 16591 N NZ . LYS I 1 179 ? 41.357 -46.100 7.284 1.00 149.86 ? 179 LYS I NZ 1 +ATOM 16592 N N . THR I 1 180 ? 36.865 -45.832 8.650 1.00 67.94 ? 180 THR I N 1 +ATOM 16593 C CA . THR I 1 180 ? 36.739 -47.035 9.434 1.00 77.04 ? 180 THR I CA 1 +ATOM 16594 C C . THR I 1 180 ? 38.128 -47.511 9.847 1.00 104.75 ? 180 THR I C 1 +ATOM 16595 O O . THR I 1 180 ? 39.058 -47.582 9.030 1.00 83.08 ? 180 THR I O 1 +ATOM 16596 C CB . THR I 1 180 ? 35.968 -48.149 8.695 1.00 77.59 ? 180 THR I CB 1 +ATOM 16597 O OG1 . THR I 1 180 ? 36.362 -49.435 9.193 1.00 66.92 ? 180 THR I OG1 1 +ATOM 16598 C CG2 . THR I 1 180 ? 36.225 -48.089 7.198 1.00 83.25 ? 180 THR I CG2 1 +ATOM 16599 N N . ILE I 1 181 ? 38.254 -47.860 11.129 1.00 133.50 ? 181 ILE I N 1 +ATOM 16600 C CA . ILE I 1 181 ? 39.518 -48.371 11.682 1.00 115.21 ? 181 ILE I CA 1 +ATOM 16601 C C . ILE I 1 181 ? 39.489 -49.902 11.812 1.00 120.64 ? 181 ILE I C 1 +ATOM 16602 O O . ILE I 1 181 ? 38.656 -50.456 12.532 1.00 140.82 ? 181 ILE I O 1 +ATOM 16603 C CB . ILE I 1 181 ? 39.821 -47.744 13.064 1.00 105.71 ? 181 ILE I CB 1 +ATOM 16604 C CG1 . ILE I 1 181 ? 39.754 -46.218 12.988 1.00 102.73 ? 181 ILE I CG1 1 +ATOM 16605 C CG2 . ILE I 1 181 ? 41.198 -48.152 13.565 1.00 136.95 ? 181 ILE I CG2 1 +ATOM 16606 C CD1 . ILE I 1 181 ? 38.706 -45.613 13.896 1.00 100.95 ? 181 ILE I CD1 1 +ATOM 16607 N N . LEU I 1 182 ? 40.376 -50.569 11.071 1.00 106.69 ? 182 LEU I N 1 +ATOM 16608 C CA . LEU I 1 182 ? 40.405 -52.026 11.001 1.00 99.05 ? 182 LEU I CA 1 +ATOM 16609 C C . LEU I 1 182 ? 41.347 -52.649 12.023 1.00 104.54 ? 182 LEU I C 1 +ATOM 16610 O O . LEU I 1 182 ? 42.484 -52.193 12.200 1.00 101.80 ? 182 LEU I O 1 +ATOM 16611 C CB . LEU I 1 182 ? 40.811 -52.467 9.594 1.00 97.80 ? 182 LEU I CB 1 +ATOM 16612 C CG . LEU I 1 182 ? 40.921 -53.979 9.384 1.00 98.16 ? 182 LEU I CG 1 +ATOM 16613 C CD1 . LEU I 1 182 ? 39.592 -54.716 9.610 1.00 96.12 ? 182 LEU I CD1 1 +ATOM 16614 C CD2 . LEU I 1 182 ? 41.461 -54.222 7.986 1.00 84.35 ? 182 LEU I CD2 1 +ATOM 16615 N N . SER I 1 183 ? 40.894 -53.747 12.626 1.00 110.64 ? 183 SER I N 1 +ATOM 16616 C CA . SER I 1 183 ? 41.732 -54.560 13.495 1.00 132.23 ? 183 SER I CA 1 +ATOM 16617 C C . SER I 1 183 ? 41.500 -56.050 13.237 1.00 134.15 ? 183 SER I C 1 +ATOM 16618 O O . SER I 1 183 ? 40.376 -56.478 13.002 1.00 120.70 ? 183 SER I O 1 +ATOM 16619 C CB . SER I 1 183 ? 41.429 -54.236 14.954 1.00 129.50 ? 183 SER I CB 1 +ATOM 16620 O OG . SER I 1 183 ? 41.184 -52.847 15.118 1.00 147.19 ? 183 SER I OG 1 +ATOM 16621 N N . TYR I 1 184 ? 42.577 -56.835 13.251 1.00 146.99 ? 184 TYR I N 1 +ATOM 16622 C CA . TYR I 1 184 ? 42.459 -58.285 13.100 1.00 134.83 ? 184 TYR I CA 1 +ATOM 16623 C C . TYR I 1 184 ? 43.557 -59.097 13.784 1.00 124.78 ? 184 TYR I C 1 +ATOM 16624 O O . TYR I 1 184 ? 44.668 -58.617 14.039 1.00 128.01 ? 184 TYR I O 1 +ATOM 16625 C CB . TYR I 1 184 ? 42.387 -58.674 11.627 1.00 120.44 ? 184 TYR I CB 1 +ATOM 16626 C CG . TYR I 1 184 ? 43.595 -58.232 10.823 1.00 97.55 ? 184 TYR I CG 1 +ATOM 16627 C CD1 . TYR I 1 184 ? 44.728 -59.029 10.731 1.00 69.87 ? 184 TYR I CD1 1 +ATOM 16628 C CD2 . TYR I 1 184 ? 43.582 -57.023 10.136 1.00 97.79 ? 184 TYR I CD2 1 +ATOM 16629 C CE1 . TYR I 1 184 ? 45.808 -58.640 9.966 1.00 63.38 ? 184 TYR I CE1 1 +ATOM 16630 C CE2 . TYR I 1 184 ? 44.653 -56.634 9.349 1.00 90.48 ? 184 TYR I CE2 1 +ATOM 16631 C CZ . TYR I 1 184 ? 45.760 -57.454 9.258 1.00 71.92 ? 184 TYR I CZ 1 +ATOM 16632 O OH . TYR I 1 184 ? 46.836 -57.027 8.518 1.00 53.81 ? 184 TYR I OH 1 +ATOM 16633 N N . GLU I 1 185 ? 43.203 -60.343 14.076 1.00 119.56 ? 185 GLU I N 1 +ATOM 16634 C CA . GLU I 1 185 ? 44.024 -61.246 14.835 1.00 137.44 ? 185 GLU I CA 1 +ATOM 16635 C C . GLU I 1 185 ? 44.032 -62.626 14.203 1.00 159.85 ? 185 GLU I C 1 +ATOM 16636 O O . GLU I 1 185 ? 43.033 -63.328 14.205 1.00 174.08 ? 185 GLU I O 1 +ATOM 16637 C CB . GLU I 1 185 ? 43.502 -61.274 16.268 1.00 136.49 ? 185 GLU I CB 1 +ATOM 16638 C CG . GLU I 1 185 ? 44.092 -62.316 17.198 1.00 149.06 ? 185 GLU I CG 1 +ATOM 16639 C CD . GLU I 1 185 ? 43.649 -62.084 18.636 1.00 156.91 ? 185 GLU I CD 1 +ATOM 16640 O OE1 . GLU I 1 185 ? 42.967 -61.073 18.901 1.00 169.93 ? 185 GLU I OE1 1 +ATOM 16641 O OE2 . GLU I 1 185 ? 44.043 -62.876 19.511 1.00 166.61 ? 185 GLU I OE2 1 +ATOM 16642 N N . VAL I 1 186 ? 45.171 -62.985 13.621 1.00 174.51 ? 186 VAL I N 1 +ATOM 16643 C CA . VAL I 1 186 ? 45.357 -64.284 12.995 1.00 154.31 ? 186 VAL I CA 1 +ATOM 16644 C C . VAL I 1 186 ? 46.169 -65.178 13.917 1.00 173.52 ? 186 VAL I C 1 +ATOM 16645 O O . VAL I 1 186 ? 47.124 -64.743 14.568 1.00 186.47 ? 186 VAL I O 1 +ATOM 16646 C CB . VAL I 1 186 ? 46.086 -64.160 11.647 1.00 126.49 ? 186 VAL I CB 1 +ATOM 16647 C CG1 . VAL I 1 186 ? 46.097 -65.497 10.928 1.00 117.23 ? 186 VAL I CG1 1 +ATOM 16648 C CG2 . VAL I 1 186 ? 45.429 -63.092 10.789 1.00 116.00 ? 186 VAL I CG2 1 +ATOM 16649 N N . GLN I 1 187 ? 45.772 -66.435 14.001 1.00 170.55 ? 187 GLN I N 1 +ATOM 16650 C CA . GLN I 1 187 ? 46.407 -67.313 14.937 1.00 176.92 ? 187 GLN I CA 1 +ATOM 16651 C C . GLN I 1 187 ? 46.344 -68.777 14.453 1.00 206.06 ? 187 GLN I C 1 +ATOM 16652 O O . GLN I 1 187 ? 45.337 -69.234 13.903 1.00 245.11 ? 187 GLN I O 1 +ATOM 16653 C CB . GLN I 1 187 ? 45.816 -67.075 16.317 1.00 143.97 ? 187 GLN I CB 1 +ATOM 16654 C CG . GLN I 1 187 ? 46.349 -68.026 17.346 1.00 146.74 ? 187 GLN I CG 1 +ATOM 16655 C CD . GLN I 1 187 ? 45.645 -67.877 18.665 1.00 139.53 ? 187 GLN I CD 1 +ATOM 16656 O OE1 . GLN I 1 187 ? 44.478 -67.517 18.703 1.00 116.57 ? 187 GLN I OE1 1 +ATOM 16657 N NE2 . GLN I 1 187 ? 46.379 -68.068 19.759 1.00 156.26 ? 187 GLN I NE2 1 +ATOM 16658 N N . ALA I 1 188 ? 47.473 -69.475 14.556 1.00 216.38 ? 188 ALA I N 1 +ATOM 16659 C CA . ALA I 1 188 ? 47.547 -70.875 14.147 1.00 188.16 ? 188 ALA I CA 1 +ATOM 16660 C C . ALA I 1 188 ? 48.401 -71.664 15.137 1.00 180.66 ? 188 ALA I C 1 +ATOM 16661 O O . ALA I 1 188 ? 49.422 -71.180 15.609 1.00 175.60 ? 188 ALA I O 1 +ATOM 16662 C CB . ALA I 1 188 ? 48.097 -70.998 12.732 1.00 160.60 ? 188 ALA I CB 1 +ATOM 16663 N N . GLY I 1 189 ? 47.971 -72.874 15.462 1.00 170.78 ? 189 GLY I N 1 +ATOM 16664 C CA . GLY I 1 189 ? 48.704 -73.722 16.385 1.00 181.85 ? 189 GLY I CA 1 +ATOM 16665 C C . GLY I 1 189 ? 48.651 -75.187 16.002 1.00 207.24 ? 189 GLY I C 1 +ATOM 16666 O O . GLY I 1 189 ? 47.604 -75.698 15.605 1.00 254.88 ? 189 GLY I O 1 +ATOM 16667 N N . VAL I 1 190 ? 49.789 -75.863 16.117 1.00 197.86 ? 190 VAL I N 1 +ATOM 16668 C CA . VAL I 1 190 ? 49.864 -77.291 15.862 1.00 166.74 ? 190 VAL I CA 1 +ATOM 16669 C C . VAL I 1 190 ? 50.177 -78.023 17.178 1.00 159.00 ? 190 VAL I C 1 +ATOM 16670 O O . VAL I 1 190 ? 51.051 -77.608 17.950 1.00 206.41 ? 190 VAL I O 1 +ATOM 16671 C CB . VAL I 1 190 ? 50.929 -77.608 14.788 1.00 137.17 ? 190 VAL I CB 1 +ATOM 16672 C CG1 . VAL I 1 190 ? 50.817 -79.064 14.360 1.00 133.28 ? 190 VAL I CG1 1 +ATOM 16673 C CG2 . VAL I 1 190 ? 50.799 -76.663 13.597 1.00 101.43 ? 190 VAL I CG2 1 +ATOM 16674 N N . PHE I 1 191 ? 49.477 -79.124 17.428 1.00 130.06 ? 191 PHE I N 1 +ATOM 16675 C CA . PHE I 1 191 ? 49.563 -79.813 18.720 1.00 145.88 ? 191 PHE I CA 1 +ATOM 16676 C C . PHE I 1 191 ? 49.717 -81.323 18.501 1.00 150.28 ? 191 PHE I C 1 +ATOM 16677 O O . PHE I 1 191 ? 48.941 -81.917 17.736 1.00 185.47 ? 191 PHE I O 1 +ATOM 16678 C CB . PHE I 1 191 ? 48.305 -79.502 19.555 1.00 148.94 ? 191 PHE I CB 1 +ATOM 16679 C CG . PHE I 1 191 ? 48.483 -79.711 21.031 1.00 146.12 ? 191 PHE I CG 1 +ATOM 16680 C CD1 . PHE I 1 191 ? 48.570 -80.991 21.558 1.00 155.84 ? 191 PHE I CD1 1 +ATOM 16681 C CD2 . PHE I 1 191 ? 48.548 -78.628 21.896 1.00 148.45 ? 191 PHE I CD2 1 +ATOM 16682 C CE1 . PHE I 1 191 ? 48.724 -81.188 22.920 1.00 148.39 ? 191 PHE I CE1 1 +ATOM 16683 C CE2 . PHE I 1 191 ? 48.717 -78.817 23.258 1.00 143.00 ? 191 PHE I CE2 1 +ATOM 16684 C CZ . PHE I 1 191 ? 48.797 -80.100 23.772 1.00 134.29 ? 191 PHE I CZ 1 +ATOM 16685 N N . LEU I 1 200 ? 54.771 -82.350 21.121 1.00 133.61 ? 200 LEU I N 1 +ATOM 16686 C CA . LEU I 1 200 ? 54.925 -81.256 20.169 1.00 165.32 ? 200 LEU I CA 1 +ATOM 16687 C C . LEU I 1 200 ? 53.765 -80.268 20.266 1.00 216.36 ? 200 LEU I C 1 +ATOM 16688 O O . LEU I 1 200 ? 52.628 -80.588 19.886 1.00 267.43 ? 200 LEU I O 1 +ATOM 16689 C CB . LEU I 1 200 ? 55.026 -81.768 18.721 1.00 151.40 ? 200 LEU I CB 1 +ATOM 16690 C CG . LEU I 1 200 ? 54.997 -80.662 17.638 1.00 126.91 ? 200 LEU I CG 1 +ATOM 16691 C CD1 . LEU I 1 200 ? 56.400 -80.374 17.141 1.00 121.18 ? 200 LEU I CD1 1 +ATOM 16692 C CD2 . LEU I 1 200 ? 54.053 -80.988 16.481 1.00 125.01 ? 200 LEU I CD2 1 +ATOM 16693 N N . GLU I 1 201 ? 54.073 -79.052 20.711 1.00 239.00 ? 201 GLU I N 1 +ATOM 16694 C CA . GLU I 1 201 ? 53.218 -77.896 20.457 1.00 235.64 ? 201 GLU I CA 1 +ATOM 16695 C C . GLU I 1 201 ? 53.978 -76.833 19.669 1.00 262.47 ? 201 GLU I C 1 +ATOM 16696 O O . GLU I 1 201 ? 55.194 -76.689 19.812 1.00 316.77 ? 201 GLU I O 1 +ATOM 16697 C CB . GLU I 1 201 ? 52.716 -77.299 21.764 1.00 190.21 ? 201 GLU I CB 1 +ATOM 16698 C CG . GLU I 1 201 ? 51.488 -76.425 21.574 1.00 193.15 ? 201 GLU I CG 1 +ATOM 16699 C CD . GLU I 1 201 ? 50.978 -75.826 22.871 1.00 228.04 ? 201 GLU I CD 1 +ATOM 16700 O OE1 . GLU I 1 201 ? 50.790 -76.580 23.852 1.00 285.82 ? 201 GLU I OE1 1 +ATOM 16701 O OE2 . GLU I 1 201 ? 50.753 -74.596 22.910 1.00 245.84 ? 201 GLU I OE2 1 +ATOM 16702 N N . GLY I 1 202 ? 53.262 -76.114 18.810 1.00 260.15 ? 202 GLY I N 1 +ATOM 16703 C CA . GLY I 1 202 ? 53.840 -74.988 18.081 1.00 244.05 ? 202 GLY I CA 1 +ATOM 16704 C C . GLY I 1 202 ? 52.782 -73.967 17.717 1.00 242.05 ? 202 GLY I C 1 +ATOM 16705 O O . GLY I 1 202 ? 51.767 -74.307 17.110 1.00 285.27 ? 202 GLY I O 1 +ATOM 16706 N N . GLU I 1 203 ? 53.006 -72.712 18.098 1.00 212.27 ? 203 GLU I N 1 +ATOM 16707 C CA . GLU I 1 203 ? 52.012 -71.667 17.876 1.00 161.97 ? 203 GLU I CA 1 +ATOM 16708 C C . GLU I 1 203 ? 52.583 -70.422 17.205 1.00 135.25 ? 203 GLU I C 1 +ATOM 16709 O O . GLU I 1 203 ? 53.661 -69.937 17.565 1.00 136.15 ? 203 GLU I O 1 +ATOM 16710 C CB . GLU I 1 203 ? 51.351 -71.285 19.193 1.00 151.33 ? 203 GLU I CB 1 +ATOM 16711 C CG . GLU I 1 203 ? 50.502 -72.407 19.783 1.00 167.19 ? 203 GLU I CG 1 +ATOM 16712 C CD . GLU I 1 203 ? 49.741 -72.017 21.043 1.00 202.48 ? 203 GLU I CD 1 +ATOM 16713 O OE1 . GLU I 1 203 ? 49.992 -70.916 21.581 1.00 258.53 ? 203 GLU I OE1 1 +ATOM 16714 O OE2 . GLU I 1 203 ? 48.913 -72.833 21.520 1.00 241.23 ? 203 GLU I OE2 1 +ATOM 16715 N N . VAL I 1 204 ? 51.846 -69.927 16.219 1.00 103.66 ? 204 VAL I N 1 +ATOM 16716 C CA . VAL I 1 204 ? 52.113 -68.641 15.610 1.00 109.70 ? 204 VAL I CA 1 +ATOM 16717 C C . VAL I 1 204 ? 50.879 -67.762 15.778 1.00 135.87 ? 204 VAL I C 1 +ATOM 16718 O O . VAL I 1 204 ? 49.746 -68.203 15.589 1.00 141.72 ? 204 VAL I O 1 +ATOM 16719 C CB . VAL I 1 204 ? 52.468 -68.783 14.115 1.00 94.65 ? 204 VAL I CB 1 +ATOM 16720 C CG1 . VAL I 1 204 ? 52.381 -67.442 13.385 1.00 86.43 ? 204 VAL I CG1 1 +ATOM 16721 C CG2 . VAL I 1 204 ? 53.861 -69.378 13.978 1.00 100.64 ? 204 VAL I CG2 1 +ATOM 16722 N N . GLY I 1 205 ? 51.114 -66.517 16.176 1.00 172.53 ? 205 GLY I N 1 +ATOM 16723 C CA . GLY I 1 205 ? 50.049 -65.533 16.306 1.00 162.82 ? 205 GLY I CA 1 +ATOM 16724 C C . GLY I 1 205 ? 50.482 -64.191 15.734 1.00 149.53 ? 205 GLY I C 1 +ATOM 16725 O O . GLY I 1 205 ? 51.665 -63.828 15.796 1.00 183.22 ? 205 GLY I O 1 +ATOM 16726 N N . TYR I 1 206 ? 49.527 -63.454 15.184 1.00 112.06 ? 206 TYR I N 1 +ATOM 16727 C CA . TYR I 1 206 ? 49.779 -62.107 14.681 1.00 100.97 ? 206 TYR I CA 1 +ATOM 16728 C C . TYR I 1 206 ? 48.543 -61.244 14.833 1.00 111.31 ? 206 TYR I C 1 +ATOM 16729 O O . TYR I 1 206 ? 47.437 -61.722 14.661 1.00 106.20 ? 206 TYR I O 1 +ATOM 16730 C CB . TYR I 1 206 ? 50.170 -62.146 13.209 1.00 92.17 ? 206 TYR I CB 1 +ATOM 16731 C CG . TYR I 1 206 ? 50.378 -60.773 12.607 1.00 93.54 ? 206 TYR I CG 1 +ATOM 16732 C CD1 . TYR I 1 206 ? 51.533 -60.035 12.883 1.00 117.00 ? 206 TYR I CD1 1 +ATOM 16733 C CD2 . TYR I 1 206 ? 49.422 -60.207 11.788 1.00 96.54 ? 206 TYR I CD2 1 +ATOM 16734 C CE1 . TYR I 1 206 ? 51.730 -58.777 12.341 1.00 124.92 ? 206 TYR I CE1 1 +ATOM 16735 C CE2 . TYR I 1 206 ? 49.607 -58.953 11.238 1.00 107.77 ? 206 TYR I CE2 1 +ATOM 16736 C CZ . TYR I 1 206 ? 50.758 -58.246 11.511 1.00 130.93 ? 206 TYR I CZ 1 +ATOM 16737 O OH . TYR I 1 206 ? 50.958 -57.020 10.924 1.00 173.59 ? 206 TYR I OH 1 +ATOM 16738 N N . THR I 1 207 ? 48.731 -59.977 15.202 1.00 136.48 ? 207 THR I N 1 +ATOM 16739 C CA . THR I 1 207 ? 47.609 -59.040 15.373 1.00 111.13 ? 207 THR I CA 1 +ATOM 16740 C C . THR I 1 207 ? 47.958 -57.672 14.793 1.00 95.48 ? 207 THR I C 1 +ATOM 16741 O O . THR I 1 207 ? 49.076 -57.170 14.972 1.00 100.21 ? 207 THR I O 1 +ATOM 16742 C CB . THR I 1 207 ? 47.218 -58.858 16.858 1.00 97.25 ? 207 THR I CB 1 +ATOM 16743 O OG1 . THR I 1 207 ? 48.320 -58.300 17.580 1.00 104.02 ? 207 THR I OG1 1 +ATOM 16744 C CG2 . THR I 1 207 ? 46.848 -60.184 17.493 1.00 93.89 ? 207 THR I CG2 1 +ATOM 16745 N N . SER I 1 208 ? 47.009 -57.080 14.084 1.00 90.52 ? 208 SER I N 1 +ATOM 16746 C CA . SER I 1 208 ? 47.243 -55.772 13.478 1.00 90.48 ? 208 SER I CA 1 +ATOM 16747 C C . SER I 1 208 ? 46.078 -54.829 13.710 1.00 99.54 ? 208 SER I C 1 +ATOM 16748 O O . SER I 1 208 ? 44.933 -55.147 13.388 1.00 145.84 ? 208 SER I O 1 +ATOM 16749 C CB . SER I 1 208 ? 47.523 -55.889 11.975 1.00 89.78 ? 208 SER I CB 1 +ATOM 16750 O OG . SER I 1 208 ? 47.605 -54.595 11.377 1.00 68.67 ? 208 SER I OG 1 +ATOM 16751 N N . ASN I 1 209 ? 46.391 -53.657 14.255 1.00 100.58 ? 209 ASN I N 1 +ATOM 16752 C CA . ASN I 1 209 ? 45.432 -52.560 14.414 1.00 92.82 ? 209 ASN I CA 1 +ATOM 16753 C C . ASN I 1 209 ? 45.816 -51.399 13.539 1.00 101.45 ? 209 ASN I C 1 +ATOM 16754 O O . ASN I 1 209 ? 46.999 -51.031 13.452 1.00 158.33 ? 209 ASN I O 1 +ATOM 16755 C CB . ASN I 1 209 ? 45.414 -52.075 15.849 1.00 89.56 ? 209 ASN I CB 1 +ATOM 16756 C CG . ASN I 1 209 ? 44.814 -53.093 16.775 1.00 86.91 ? 209 ASN I CG 1 +ATOM 16757 O OD1 . ASN I 1 209 ? 43.605 -53.149 16.937 1.00 116.86 ? 209 ASN I OD1 1 +ATOM 16758 N ND2 . ASN I 1 209 ? 45.658 -53.864 17.432 1.00 88.60 ? 209 ASN I ND2 1 +ATOM 16759 N N . GLU I 1 210 ? 44.828 -50.815 12.889 1.00 86.49 ? 210 GLU I N 1 +ATOM 16760 C CA . GLU I 1 210 ? 45.060 -49.556 12.208 1.00 96.76 ? 210 GLU I CA 1 +ATOM 16761 C C . GLU I 1 210 ? 45.289 -48.495 13.267 1.00 77.61 ? 210 GLU I C 1 +ATOM 16762 O O . GLU I 1 210 ? 44.666 -48.513 14.329 1.00 65.64 ? 210 GLU I O 1 +ATOM 16763 C CB . GLU I 1 210 ? 43.852 -49.186 11.348 1.00 125.10 ? 210 GLU I CB 1 +ATOM 16764 C CG . GLU I 1 210 ? 44.175 -48.643 9.967 1.00 125.38 ? 210 GLU I CG 1 +ATOM 16765 C CD . GLU I 1 210 ? 42.972 -48.690 9.020 1.00 124.96 ? 210 GLU I CD 1 +ATOM 16766 O OE1 . GLU I 1 210 ? 42.063 -49.546 9.183 1.00 73.36 ? 210 GLU I OE1 1 +ATOM 16767 O OE2 . GLU I 1 210 ? 42.958 -47.862 8.084 1.00 145.31 ? 210 GLU I OE2 1 +ATOM 16768 N N . PRO I 1 211 ? 46.173 -47.558 12.974 1.00 78.32 ? 211 PRO I N 1 +ATOM 16769 C CA . PRO I 1 211 ? 46.282 -46.435 13.881 1.00 120.40 ? 211 PRO I CA 1 +ATOM 16770 C C . PRO I 1 211 ? 45.088 -45.473 13.744 1.00 117.20 ? 211 PRO I C 1 +ATOM 16771 O O . PRO I 1 211 ? 44.827 -44.975 12.652 1.00 52.81 ? 211 PRO I O 1 +ATOM 16772 C CB . PRO I 1 211 ? 47.605 -45.759 13.454 1.00 142.39 ? 211 PRO I CB 1 +ATOM 16773 C CG . PRO I 1 211 ? 48.333 -46.787 12.650 1.00 112.74 ? 211 PRO I CG 1 +ATOM 16774 C CD . PRO I 1 211 ? 47.244 -47.561 11.974 1.00 86.00 ? 211 PRO I CD 1 +ATOM 16775 N N . VAL I 1 212 ? 44.444 -45.171 14.876 1.00 133.85 ? 212 VAL I N 1 +ATOM 16776 C CA . VAL I 1 212 ? 43.333 -44.223 14.927 1.00 102.32 ? 212 VAL I CA 1 +ATOM 16777 C C . VAL I 1 212 ? 43.829 -42.834 14.569 1.00 85.45 ? 212 VAL I C 1 +ATOM 16778 O O . VAL I 1 212 ? 43.202 -42.104 13.792 1.00 92.63 ? 212 VAL I O 1 +ATOM 16779 C CB . VAL I 1 212 ? 42.716 -44.149 16.334 1.00 91.60 ? 212 VAL I CB 1 +ATOM 16780 C CG1 . VAL I 1 212 ? 41.475 -43.281 16.299 1.00 89.09 ? 212 VAL I CG1 1 +ATOM 16781 C CG2 . VAL I 1 212 ? 42.380 -45.547 16.862 1.00 103.47 ? 212 VAL I CG2 1 +ATOM 16782 N N . MET I 1 213 ? 44.989 -42.511 15.118 1.00 64.25 ? 213 MET I N 1 +ATOM 16783 C CA . MET I 1 213 ? 45.842 -41.419 14.659 1.00 82.02 ? 213 MET I CA 1 +ATOM 16784 C C . MET I 1 213 ? 45.845 -41.163 13.138 1.00 82.95 ? 213 MET I C 1 +ATOM 16785 O O . MET I 1 213 ? 45.595 -40.039 12.653 1.00 79.72 ? 213 MET I O 1 +ATOM 16786 C CB . MET I 1 213 ? 47.245 -41.814 15.121 1.00 99.76 ? 213 MET I CB 1 +ATOM 16787 C CG . MET I 1 213 ? 48.363 -40.823 14.931 1.00 121.95 ? 213 MET I CG 1 +ATOM 16788 S SD . MET I 1 213 ? 49.845 -41.641 15.606 1.00 140.83 ? 213 MET I SD 1 +ATOM 16789 C CE . MET I 1 213 ? 50.676 -41.835 14.036 1.00 166.21 ? 213 MET I CE 1 +ATOM 16790 N N . LEU I 1 214 ? 46.064 -42.235 12.391 1.00 89.36 ? 214 LEU I N 1 +ATOM 16791 C CA . LEU I 1 214 ? 46.344 -42.147 10.961 1.00 113.02 ? 214 LEU I CA 1 +ATOM 16792 C C . LEU I 1 214 ? 45.038 -42.083 10.176 1.00 118.84 ? 214 LEU I C 1 +ATOM 16793 O O . LEU I 1 214 ? 44.965 -41.468 9.113 1.00 108.73 ? 214 LEU I O 1 +ATOM 16794 C CB . LEU I 1 214 ? 47.166 -43.367 10.518 1.00 138.55 ? 214 LEU I CB 1 +ATOM 16795 C CG . LEU I 1 214 ? 48.362 -43.166 9.566 1.00 140.81 ? 214 LEU I CG 1 +ATOM 16796 C CD1 . LEU I 1 214 ? 49.420 -42.209 10.158 1.00 162.26 ? 214 LEU I CD1 1 +ATOM 16797 C CD2 . LEU I 1 214 ? 48.967 -44.535 9.222 1.00 103.53 ? 214 LEU I CD2 1 +ATOM 16798 N N . CYS I 1 215 ? 43.996 -42.694 10.733 1.00 122.62 ? 215 CYS I N 1 +ATOM 16799 C CA . CYS I 1 215 ? 42.648 -42.620 10.157 1.00 114.75 ? 215 CYS I CA 1 +ATOM 16800 C C . CYS I 1 215 ? 42.029 -41.220 10.309 1.00 95.97 ? 215 CYS I C 1 +ATOM 16801 O O . CYS I 1 215 ? 41.385 -40.687 9.390 1.00 54.88 ? 215 CYS I O 1 +ATOM 16802 C CB . CYS I 1 215 ? 41.732 -43.620 10.850 1.00 119.14 ? 215 CYS I CB 1 +ATOM 16803 S SG . CYS I 1 215 ? 42.219 -45.329 10.607 1.00 138.20 ? 215 CYS I SG 1 +ATOM 16804 N N . LEU I 1 216 ? 42.239 -40.636 11.485 1.00 97.93 ? 216 LEU I N 1 +ATOM 16805 C CA . LEU I 1 216 ? 41.857 -39.263 11.719 1.00 97.31 ? 216 LEU I CA 1 +ATOM 16806 C C . LEU I 1 216 ? 42.513 -38.362 10.676 1.00 99.71 ? 216 LEU I C 1 +ATOM 16807 O O . LEU I 1 216 ? 41.831 -37.547 10.033 1.00 121.50 ? 216 LEU I O 1 +ATOM 16808 C CB . LEU I 1 216 ? 42.248 -38.817 13.131 1.00 80.95 ? 216 LEU I CB 1 +ATOM 16809 C CG . LEU I 1 216 ? 41.906 -37.357 13.457 1.00 70.44 ? 216 LEU I CG 1 +ATOM 16810 C CD1 . LEU I 1 216 ? 40.425 -37.052 13.302 1.00 69.35 ? 216 LEU I CD1 1 +ATOM 16811 C CD2 . LEU I 1 216 ? 42.332 -37.046 14.882 1.00 93.64 ? 216 LEU I CD2 1 +ATOM 16812 N N . MET I 1 217 ? 43.816 -38.554 10.472 1.00 78.84 ? 217 MET I N 1 +ATOM 16813 C CA . MET I 1 217 ? 44.564 -37.690 9.584 1.00 91.47 ? 217 MET I CA 1 +ATOM 16814 C C . MET I 1 217 ? 44.041 -37.836 8.159 1.00 104.17 ? 217 MET I C 1 +ATOM 16815 O O . MET I 1 217 ? 43.752 -36.837 7.480 1.00 146.17 ? 217 MET I O 1 +ATOM 16816 C CB . MET I 1 217 ? 46.053 -37.995 9.645 1.00 96.21 ? 217 MET I CB 1 +ATOM 16817 C CG . MET I 1 217 ? 46.927 -36.738 9.673 1.00 90.44 ? 217 MET I CG 1 +ATOM 16818 S SD . MET I 1 217 ? 46.915 -35.853 8.092 1.00 137.78 ? 217 MET I SD 1 +ATOM 16819 C CE . MET I 1 217 ? 47.768 -34.329 8.501 1.00 106.52 ? 217 MET I CE 1 +ATOM 16820 N N . SER I 1 218 ? 43.830 -39.078 7.742 1.00 101.52 ? 218 SER I N 1 +ATOM 16821 C CA . SER I 1 218 ? 43.279 -39.374 6.409 1.00 111.65 ? 218 SER I CA 1 +ATOM 16822 C C . SER I 1 218 ? 41.933 -38.684 6.162 1.00 85.98 ? 218 SER I C 1 +ATOM 16823 O O . SER I 1 218 ? 41.735 -38.019 5.146 1.00 51.82 ? 218 SER I O 1 +ATOM 16824 C CB . SER I 1 218 ? 43.112 -40.895 6.242 1.00 125.20 ? 218 SER I CB 1 +ATOM 16825 O OG . SER I 1 218 ? 42.812 -41.237 4.900 1.00 109.79 ? 218 SER I OG 1 +ATOM 16826 N N . ALA I 1 219 ? 41.027 -38.846 7.117 1.00 83.82 ? 219 ALA I N 1 +ATOM 16827 C CA . ALA I 1 219 ? 39.691 -38.326 6.972 1.00 90.89 ? 219 ALA I CA 1 +ATOM 16828 C C . ALA I 1 219 ? 39.691 -36.791 6.895 1.00 87.86 ? 219 ALA I C 1 +ATOM 16829 O O . ALA I 1 219 ? 38.868 -36.177 6.196 1.00 78.76 ? 219 ALA I O 1 +ATOM 16830 C CB . ALA I 1 219 ? 38.834 -38.825 8.125 1.00 100.59 ? 219 ALA I CB 1 +ATOM 16831 N N . ILE I 1 220 ? 40.593 -36.163 7.643 1.00 85.79 ? 220 ILE I N 1 +ATOM 16832 C CA . ILE I 1 220 ? 40.695 -34.701 7.633 1.00 90.41 ? 220 ILE I CA 1 +ATOM 16833 C C . ILE I 1 220 ? 41.186 -34.194 6.265 1.00 91.80 ? 220 ILE I C 1 +ATOM 16834 O O . ILE I 1 220 ? 40.646 -33.216 5.727 1.00 76.81 ? 220 ILE I O 1 +ATOM 16835 C CB . ILE I 1 220 ? 41.619 -34.169 8.760 1.00 74.51 ? 220 ILE I CB 1 +ATOM 16836 C CG1 . ILE I 1 220 ? 40.962 -34.410 10.129 1.00 61.67 ? 220 ILE I CG1 1 +ATOM 16837 C CG2 . ILE I 1 220 ? 41.946 -32.679 8.535 1.00 59.03 ? 220 ILE I CG2 1 +ATOM 16838 C CD1 . ILE I 1 220 ? 41.907 -34.313 11.295 1.00 50.15 ? 220 ILE I CD1 1 +ATOM 16839 N N . GLU I 1 221 ? 42.153 -34.898 5.685 1.00 93.27 ? 221 GLU I N 1 +ATOM 16840 C CA . GLU I 1 221 ? 42.621 -34.583 4.337 1.00 115.54 ? 221 GLU I CA 1 +ATOM 16841 C C . GLU I 1 221 ? 41.454 -34.651 3.331 1.00 131.07 ? 221 GLU I C 1 +ATOM 16842 O O . GLU I 1 221 ? 41.217 -33.694 2.567 1.00 124.22 ? 221 GLU I O 1 +ATOM 16843 C CB . GLU I 1 221 ? 43.734 -35.550 3.925 1.00 106.52 ? 221 GLU I CB 1 +ATOM 16844 C CG . GLU I 1 221 ? 45.054 -35.287 4.621 1.00 93.47 ? 221 GLU I CG 1 +ATOM 16845 C CD . GLU I 1 221 ? 46.019 -36.463 4.561 1.00 106.38 ? 221 GLU I CD 1 +ATOM 16846 O OE1 . GLU I 1 221 ? 45.581 -37.648 4.597 1.00 106.61 ? 221 GLU I OE1 1 +ATOM 16847 O OE2 . GLU I 1 221 ? 47.234 -36.189 4.450 1.00 99.57 ? 221 GLU I OE2 1 +ATOM 16848 N N . THR I 1 222 ? 40.727 -35.773 3.363 1.00 101.79 ? 222 THR I N 1 +ATOM 16849 C CA . THR I 1 222 ? 39.557 -35.996 2.516 1.00 85.54 ? 222 THR I CA 1 +ATOM 16850 C C . THR I 1 222 ? 38.548 -34.850 2.635 1.00 81.29 ? 222 THR I C 1 +ATOM 16851 O O . THR I 1 222 ? 38.080 -34.313 1.626 1.00 61.33 ? 222 THR I O 1 +ATOM 16852 C CB . THR I 1 222 ? 38.852 -37.296 2.930 1.00 89.99 ? 222 THR I CB 1 +ATOM 16853 O OG1 . THR I 1 222 ? 39.641 -38.432 2.541 1.00 89.36 ? 222 THR I OG1 1 +ATOM 16854 C CG2 . THR I 1 222 ? 37.428 -37.374 2.322 1.00 93.09 ? 222 THR I CG2 1 +ATOM 16855 N N . GLY I 1 223 ? 38.237 -34.479 3.878 1.00 73.17 ? 223 GLY I N 1 +ATOM 16856 C CA . GLY I 1 223 ? 37.401 -33.318 4.154 1.00 72.10 ? 223 GLY I CA 1 +ATOM 16857 C C . GLY I 1 223 ? 37.898 -32.014 3.518 1.00 79.20 ? 223 GLY I C 1 +ATOM 16858 O O . GLY I 1 223 ? 37.106 -31.236 2.977 1.00 83.62 ? 223 GLY I O 1 +ATOM 16859 N N . VAL I 1 224 ? 39.210 -31.787 3.549 1.00 81.06 ? 224 VAL I N 1 +ATOM 16860 C CA . VAL I 1 224 ? 39.777 -30.586 2.957 1.00 91.34 ? 224 VAL I CA 1 +ATOM 16861 C C . VAL I 1 224 ? 39.547 -30.584 1.452 1.00 95.27 ? 224 VAL I C 1 +ATOM 16862 O O . VAL I 1 224 ? 39.191 -29.552 0.877 1.00 95.21 ? 224 VAL I O 1 +ATOM 16863 C CB . VAL I 1 224 ? 41.282 -30.468 3.230 1.00 118.01 ? 224 VAL I CB 1 +ATOM 16864 C CG1 . VAL I 1 224 ? 41.877 -29.296 2.457 1.00 113.63 ? 224 VAL I CG1 1 +ATOM 16865 C CG2 . VAL I 1 224 ? 41.538 -30.307 4.722 1.00 137.62 ? 224 VAL I CG2 1 +ATOM 16866 N N . ILE I 1 225 ? 39.734 -31.738 0.817 1.00 86.75 ? 225 ILE I N 1 +ATOM 16867 C CA . ILE I 1 225 ? 39.485 -31.841 -0.616 1.00 85.34 ? 225 ILE I CA 1 +ATOM 16868 C C . ILE I 1 225 ? 38.037 -31.484 -0.917 1.00 87.27 ? 225 ILE I C 1 +ATOM 16869 O O . ILE I 1 225 ? 37.778 -30.646 -1.787 1.00 73.29 ? 225 ILE I O 1 +ATOM 16870 C CB . ILE I 1 225 ? 39.817 -33.245 -1.167 1.00 90.83 ? 225 ILE I CB 1 +ATOM 16871 C CG1 . ILE I 1 225 ? 41.324 -33.477 -1.102 1.00 113.44 ? 225 ILE I CG1 1 +ATOM 16872 C CG2 . ILE I 1 225 ? 39.362 -33.381 -2.609 1.00 77.02 ? 225 ILE I CG2 1 +ATOM 16873 C CD1 . ILE I 1 225 ? 41.721 -34.932 -1.209 1.00 136.69 ? 225 ILE I CD1 1 +ATOM 16874 N N . PHE I 1 226 ? 37.093 -32.148 -0.234 1.00 83.60 ? 226 PHE I N 1 +ATOM 16875 C CA . PHE I 1 226 ? 35.654 -31.890 -0.452 1.00 85.59 ? 226 PHE I CA 1 +ATOM 16876 C C . PHE I 1 226 ? 35.318 -30.394 -0.266 1.00 84.93 ? 226 PHE I C 1 +ATOM 16877 O O . PHE I 1 226 ? 34.430 -29.869 -0.926 1.00 79.47 ? 226 PHE I O 1 +ATOM 16878 C CB . PHE I 1 226 ? 34.772 -32.752 0.478 1.00 79.88 ? 226 PHE I CB 1 +ATOM 16879 C CG . PHE I 1 226 ? 34.570 -34.178 0.025 1.00 80.91 ? 226 PHE I CG 1 +ATOM 16880 C CD1 . PHE I 1 226 ? 33.957 -34.457 -1.192 1.00 101.83 ? 226 PHE I CD1 1 +ATOM 16881 C CD2 . PHE I 1 226 ? 34.902 -35.243 0.856 1.00 80.34 ? 226 PHE I CD2 1 +ATOM 16882 C CE1 . PHE I 1 226 ? 33.750 -35.769 -1.612 1.00 81.52 ? 226 PHE I CE1 1 +ATOM 16883 C CE2 . PHE I 1 226 ? 34.672 -36.545 0.459 1.00 83.22 ? 226 PHE I CE2 1 +ATOM 16884 C CZ . PHE I 1 226 ? 34.111 -36.807 -0.791 1.00 85.14 ? 226 PHE I CZ 1 +ATOM 16885 N N . LEU I 1 227 ? 36.000 -29.741 0.670 1.00 77.13 ? 227 LEU I N 1 +ATOM 16886 C CA . LEU I 1 227 ? 35.801 -28.321 0.915 1.00 72.36 ? 227 LEU I CA 1 +ATOM 16887 C C . LEU I 1 227 ? 36.284 -27.482 -0.253 1.00 78.19 ? 227 LEU I C 1 +ATOM 16888 O O . LEU I 1 227 ? 35.598 -26.579 -0.683 1.00 65.93 ? 227 LEU I O 1 +ATOM 16889 C CB . LEU I 1 227 ? 36.553 -27.929 2.168 1.00 88.67 ? 227 LEU I CB 1 +ATOM 16890 C CG . LEU I 1 227 ? 35.896 -28.303 3.501 1.00 92.61 ? 227 LEU I CG 1 +ATOM 16891 C CD1 . LEU I 1 227 ? 36.790 -28.162 4.728 1.00 79.79 ? 227 LEU I CD1 1 +ATOM 16892 C CD2 . LEU I 1 227 ? 34.619 -27.516 3.708 1.00 94.88 ? 227 LEU I CD2 1 +ATOM 16893 N N . ILE I 1 228 ? 37.441 -27.834 -0.811 1.00 101.04 ? 228 ILE I N 1 +ATOM 16894 C CA . ILE I 1 228 ? 37.993 -27.098 -1.943 1.00 100.93 ? 228 ILE I CA 1 +ATOM 16895 C C . ILE I 1 228 ? 37.081 -27.281 -3.139 1.00 99.29 ? 228 ILE I C 1 +ATOM 16896 O O . ILE I 1 228 ? 36.749 -26.312 -3.832 1.00 111.04 ? 228 ILE I O 1 +ATOM 16897 C CB . ILE I 1 228 ? 39.424 -27.566 -2.328 1.00 99.44 ? 228 ILE I CB 1 +ATOM 16898 C CG1 . ILE I 1 228 ? 40.409 -27.275 -1.196 1.00 107.64 ? 228 ILE I CG1 1 +ATOM 16899 C CG2 . ILE I 1 228 ? 39.905 -26.832 -3.566 1.00 90.12 ? 228 ILE I CG2 1 +ATOM 16900 C CD1 . ILE I 1 228 ? 41.733 -27.996 -1.309 1.00 96.22 ? 228 ILE I CD1 1 +ATOM 16901 N N . ASN I 1 229 ? 36.697 -28.526 -3.401 1.00 77.95 ? 229 ASN I N 1 +ATOM 16902 C CA . ASN I 1 229 ? 35.872 -28.832 -4.560 1.00 96.14 ? 229 ASN I CA 1 +ATOM 16903 C C . ASN I 1 229 ? 34.546 -28.092 -4.444 1.00 84.68 ? 229 ASN I C 1 +ATOM 16904 O O . ASN I 1 229 ? 34.046 -27.512 -5.424 1.00 74.17 ? 229 ASN I O 1 +ATOM 16905 C CB . ASN I 1 229 ? 35.663 -30.358 -4.664 1.00 121.34 ? 229 ASN I CB 1 +ATOM 16906 C CG . ASN I 1 229 ? 35.161 -30.815 -6.033 1.00 130.14 ? 229 ASN I CG 1 +ATOM 16907 O OD1 . ASN I 1 229 ? 35.300 -30.099 -7.029 1.00 166.45 ? 229 ASN I OD1 1 +ATOM 16908 N ND2 . ASN I 1 229 ? 34.534 -31.992 -6.070 1.00 94.63 ? 229 ASN I ND2 1 +ATOM 16909 N N . ASP I 1 230 ? 33.971 -28.140 -3.251 1.00 64.93 ? 230 ASP I N 1 +ATOM 16910 C CA . ASP I 1 230 ? 32.712 -27.475 -3.007 1.00 70.83 ? 230 ASP I CA 1 +ATOM 16911 C C . ASP I 1 230 ? 32.852 -25.983 -3.276 1.00 74.73 ? 230 ASP I C 1 +ATOM 16912 O O . ASP I 1 230 ? 31.952 -25.329 -3.799 1.00 81.34 ? 230 ASP I O 1 +ATOM 16913 C CB . ASP I 1 230 ? 32.267 -27.729 -1.576 1.00 83.89 ? 230 ASP I CB 1 +ATOM 16914 C CG . ASP I 1 230 ? 30.889 -27.156 -1.287 1.00 117.67 ? 230 ASP I CG 1 +ATOM 16915 O OD1 . ASP I 1 230 ? 29.900 -27.755 -1.755 1.00 131.80 ? 230 ASP I OD1 1 +ATOM 16916 O OD2 . ASP I 1 230 ? 30.787 -26.154 -0.530 1.00 209.06 ? 230 ASP I OD2 1 +ATOM 16917 N N . GLY I 1 231 ? 33.962 -25.419 -2.831 1.00 112.41 ? 231 GLY I N 1 +ATOM 16918 C CA . GLY I 1 231 ? 34.193 -23.986 -2.975 1.00 126.71 ? 231 GLY I CA 1 +ATOM 16919 C C . GLY I 1 231 ? 34.329 -23.627 -4.445 1.00 99.28 ? 231 GLY I C 1 +ATOM 16920 O O . GLY I 1 231 ? 33.983 -22.502 -4.847 1.00 81.76 ? 231 GLY I O 1 +ATOM 16921 N N . ILE I 1 232 ? 34.901 -24.554 -5.219 1.00 77.99 ? 232 ILE I N 1 +ATOM 16922 C CA . ILE I 1 232 ? 35.124 -24.317 -6.634 1.00 101.27 ? 232 ILE I CA 1 +ATOM 16923 C C . ILE I 1 232 ? 33.765 -24.210 -7.279 1.00 125.39 ? 232 ILE I C 1 +ATOM 16924 O O . ILE I 1 232 ? 33.508 -23.268 -8.040 1.00 132.98 ? 232 ILE I O 1 +ATOM 16925 C CB . ILE I 1 232 ? 35.950 -25.450 -7.283 1.00 112.89 ? 232 ILE I CB 1 +ATOM 16926 C CG1 . ILE I 1 232 ? 37.432 -25.300 -6.909 1.00 117.54 ? 232 ILE I CG1 1 +ATOM 16927 C CG2 . ILE I 1 232 ? 35.788 -25.453 -8.808 1.00 137.38 ? 232 ILE I CG2 1 +ATOM 16928 C CD1 . ILE I 1 232 ? 38.253 -26.553 -7.126 1.00 116.11 ? 232 ILE I CD1 1 +ATOM 16929 N N . ASP I 1 233 ? 32.901 -25.178 -6.976 1.00 141.96 ? 233 ASP I N 1 +ATOM 16930 C CA . ASP I 1 233 ? 31.527 -25.195 -7.501 1.00 165.70 ? 233 ASP I CA 1 +ATOM 16931 C C . ASP I 1 233 ? 30.767 -23.918 -7.145 1.00 143.87 ? 233 ASP I C 1 +ATOM 16932 O O . ASP I 1 233 ? 30.174 -23.278 -8.008 1.00 142.36 ? 233 ASP I O 1 +ATOM 16933 C CB . ASP I 1 233 ? 30.753 -26.399 -6.952 1.00 181.20 ? 233 ASP I CB 1 +ATOM 16934 C CG . ASP I 1 233 ? 31.302 -27.740 -7.437 1.00 180.45 ? 233 ASP I CG 1 +ATOM 16935 O OD1 . ASP I 1 233 ? 32.401 -27.764 -8.037 1.00 177.49 ? 233 ASP I OD1 1 +ATOM 16936 O OD2 . ASP I 1 233 ? 30.637 -28.774 -7.183 1.00 139.93 ? 233 ASP I OD2 1 +ATOM 16937 N N . ARG I 1 234 ? 30.836 -23.529 -5.880 1.00 137.72 ? 234 ARG I N 1 +ATOM 16938 C CA . ARG I 1 234 ? 30.068 -22.398 -5.391 1.00 143.48 ? 234 ARG I CA 1 +ATOM 16939 C C . ARG I 1 234 ? 30.684 -21.018 -5.678 1.00 155.85 ? 234 ARG I C 1 +ATOM 16940 O O . ARG I 1 234 ? 30.107 -19.981 -5.317 1.00 198.73 ? 234 ARG I O 1 +ATOM 16941 C CB . ARG I 1 234 ? 29.837 -22.561 -3.893 1.00 159.06 ? 234 ARG I CB 1 +ATOM 16942 C CG . ARG I 1 234 ? 28.837 -23.656 -3.599 1.00 151.57 ? 234 ARG I CG 1 +ATOM 16943 C CD . ARG I 1 234 ? 28.959 -24.192 -2.188 1.00 157.73 ? 234 ARG I CD 1 +ATOM 16944 N NE . ARG I 1 234 ? 28.005 -25.290 -2.043 1.00 161.87 ? 234 ARG I NE 1 +ATOM 16945 C CZ . ARG I 1 234 ? 27.016 -25.324 -1.158 1.00 175.12 ? 234 ARG I CZ 1 +ATOM 16946 N NH1 . ARG I 1 234 ? 26.916 -24.356 -0.248 1.00 220.40 ? 234 ARG I NH1 1 +ATOM 16947 N NH2 . ARG I 1 234 ? 26.145 -26.335 -1.163 1.00 123.05 ? 234 ARG I NH2 1 +ATOM 16948 N N . GLY I 1 235 ? 31.851 -20.996 -6.313 1.00 147.73 ? 235 GLY I N 1 +ATOM 16949 C CA . GLY I 1 235 ? 32.483 -19.737 -6.709 1.00 132.24 ? 235 GLY I CA 1 +ATOM 16950 C C . GLY I 1 235 ? 33.152 -18.985 -5.575 1.00 96.14 ? 235 GLY I C 1 +ATOM 16951 O O . GLY I 1 235 ? 33.176 -17.755 -5.583 1.00 50.54 ? 235 GLY I O 1 +ATOM 16952 N N . LEU I 1 236 ? 33.672 -19.724 -4.588 1.00 102.68 ? 236 LEU I N 1 +ATOM 16953 C CA . LEU I 1 236 ? 34.506 -19.112 -3.545 1.00 107.38 ? 236 LEU I CA 1 +ATOM 16954 C C . LEU I 1 236 ? 35.860 -18.803 -4.148 1.00 106.19 ? 236 LEU I C 1 +ATOM 16955 O O . LEU I 1 236 ? 36.372 -17.687 -4.008 1.00 138.02 ? 236 LEU I O 1 +ATOM 16956 C CB . LEU I 1 236 ? 34.689 -20.026 -2.317 1.00 115.06 ? 236 LEU I CB 1 +ATOM 16957 C CG . LEU I 1 236 ? 33.592 -20.015 -1.242 1.00 126.41 ? 236 LEU I CG 1 +ATOM 16958 C CD1 . LEU I 1 236 ? 32.392 -20.856 -1.667 1.00 126.63 ? 236 LEU I CD1 1 +ATOM 16959 C CD2 . LEU I 1 236 ? 34.144 -20.538 0.070 1.00 129.64 ? 236 LEU I CD2 1 +ATOM 16960 N N . TRP I 1 237 ? 36.428 -19.786 -4.838 1.00 89.40 ? 237 TRP I N 1 +ATOM 16961 C CA . TRP I 1 237 ? 37.745 -19.632 -5.447 1.00 91.87 ? 237 TRP I CA 1 +ATOM 16962 C C . TRP I 1 237 ? 37.774 -20.282 -6.829 1.00 112.84 ? 237 TRP I C 1 +ATOM 16963 O O . TRP I 1 237 ? 36.872 -21.046 -7.182 1.00 106.50 ? 237 TRP I O 1 +ATOM 16964 C CB . TRP I 1 237 ? 38.812 -20.227 -4.538 1.00 84.24 ? 237 TRP I CB 1 +ATOM 16965 C CG . TRP I 1 237 ? 38.322 -21.402 -3.773 1.00 88.41 ? 237 TRP I CG 1 +ATOM 16966 C CD1 . TRP I 1 237 ? 38.017 -22.624 -4.276 1.00 101.14 ? 237 TRP I CD1 1 +ATOM 16967 C CD2 . TRP I 1 237 ? 38.115 -21.488 -2.356 1.00 102.39 ? 237 TRP I CD2 1 +ATOM 16968 N NE1 . TRP I 1 237 ? 37.640 -23.479 -3.264 1.00 105.92 ? 237 TRP I NE1 1 +ATOM 16969 C CE2 . TRP I 1 237 ? 37.704 -22.812 -2.074 1.00 102.91 ? 237 TRP I CE2 1 +ATOM 16970 C CE3 . TRP I 1 237 ? 38.235 -20.579 -1.300 1.00 120.44 ? 237 TRP I CE3 1 +ATOM 16971 C CZ2 . TRP I 1 237 ? 37.399 -23.247 -0.789 1.00 115.62 ? 237 TRP I CZ2 1 +ATOM 16972 C CZ3 . TRP I 1 237 ? 37.914 -21.006 -0.021 1.00 131.20 ? 237 TRP I CZ3 1 +ATOM 16973 C CH2 . TRP I 1 237 ? 37.502 -22.331 0.222 1.00 147.03 ? 237 TRP I CH2 1 +ATOM 16974 N N . ASP I 1 238 ? 38.800 -19.953 -7.614 1.00 135.52 ? 238 ASP I N 1 +ATOM 16975 C CA . ASP I 1 238 ? 38.864 -20.365 -9.018 1.00 149.44 ? 238 ASP I CA 1 +ATOM 16976 C C . ASP I 1 238 ? 40.184 -21.036 -9.387 1.00 136.39 ? 238 ASP I C 1 +ATOM 16977 O O . ASP I 1 238 ? 41.247 -20.687 -8.863 1.00 96.75 ? 238 ASP I O 1 +ATOM 16978 C CB . ASP I 1 238 ? 38.627 -19.173 -9.949 1.00 145.47 ? 238 ASP I CB 1 +ATOM 16979 C CG . ASP I 1 238 ? 37.304 -18.477 -9.678 1.00 140.13 ? 238 ASP I CG 1 +ATOM 16980 O OD1 . ASP I 1 238 ? 37.253 -17.681 -8.724 1.00 124.30 ? 238 ASP I OD1 1 +ATOM 16981 O OD2 . ASP I 1 238 ? 36.320 -18.714 -10.412 1.00 124.09 ? 238 ASP I OD2 1 +ATOM 16982 N N . LEU I 1 239 ? 40.102 -21.971 -10.333 1.00 147.31 ? 239 LEU I N 1 +ATOM 16983 C CA . LEU I 1 239 ? 41.266 -22.711 -10.798 1.00 167.94 ? 239 LEU I CA 1 +ATOM 16984 C C . LEU I 1 239 ? 42.111 -21.852 -11.731 1.00 182.80 ? 239 LEU I C 1 +ATOM 16985 O O . LEU I 1 239 ? 41.585 -21.044 -12.499 1.00 138.66 ? 239 LEU I O 1 +ATOM 16986 C CB . LEU I 1 239 ? 40.842 -23.992 -11.533 1.00 166.55 ? 239 LEU I CB 1 +ATOM 16987 C CG . LEU I 1 239 ? 40.364 -25.203 -10.733 1.00 154.83 ? 239 LEU I CG 1 +ATOM 16988 C CD1 . LEU I 1 239 ? 40.099 -26.389 -11.651 1.00 155.95 ? 239 LEU I CD1 1 +ATOM 16989 C CD2 . LEU I 1 239 ? 41.385 -25.581 -9.680 1.00 162.70 ? 239 LEU I CD2 1 +ATOM 16990 N N . GLN I 1 240 ? 43.427 -22.039 -11.648 1.00 184.96 ? 240 GLN I N 1 +ATOM 16991 C CA . GLN I 1 240 ? 44.350 -21.451 -12.611 1.00 162.43 ? 240 GLN I CA 1 +ATOM 16992 C C . GLN I 1 240 ? 43.936 -21.841 -14.031 1.00 159.39 ? 240 GLN I C 1 +ATOM 16993 O O . GLN I 1 240 ? 43.693 -20.980 -14.880 1.00 154.60 ? 240 GLN I O 1 +ATOM 16994 C CB . GLN I 1 240 ? 45.788 -21.917 -12.325 1.00 142.59 ? 240 GLN I CB 1 +ATOM 16995 C CG . GLN I 1 240 ? 46.846 -21.205 -13.160 1.00 136.97 ? 240 GLN I CG 1 +ATOM 16996 C CD . GLN I 1 240 ? 46.936 -19.724 -12.836 1.00 151.59 ? 240 GLN I CD 1 +ATOM 16997 O OE1 . GLN I 1 240 ? 47.542 -19.332 -11.835 1.00 178.81 ? 240 GLN I OE1 1 +ATOM 16998 N NE2 . GLN I 1 240 ? 46.275 -18.894 -13.644 1.00 148.79 ? 240 GLN I NE2 1 +ATOM 16999 N N . ASN I 1 241 ? 43.851 -23.147 -14.266 1.00 167.80 ? 241 ASN I N 1 +ATOM 17000 C CA . ASN I 1 241 ? 43.459 -23.699 -15.558 1.00 158.01 ? 241 ASN I CA 1 +ATOM 17001 C C . ASN I 1 241 ? 42.036 -24.223 -15.517 1.00 151.45 ? 241 ASN I C 1 +ATOM 17002 O O . ASN I 1 241 ? 41.764 -25.254 -14.888 1.00 148.30 ? 241 ASN I O 1 +ATOM 17003 C CB . ASN I 1 241 ? 44.393 -24.845 -15.942 1.00 157.36 ? 241 ASN I CB 1 +ATOM 17004 C CG . ASN I 1 241 ? 45.444 -24.423 -16.937 1.00 175.64 ? 241 ASN I CG 1 +ATOM 17005 O OD1 . ASN I 1 241 ? 45.320 -24.707 -18.124 1.00 186.11 ? 241 ASN I OD1 1 +ATOM 17006 N ND2 . ASN I 1 241 ? 46.476 -23.720 -16.466 1.00 187.21 ? 241 ASN I ND2 1 +ATOM 17007 N N . LYS I 1 242 ? 41.138 -23.530 -16.212 1.00 133.37 ? 242 LYS I N 1 +ATOM 17008 C CA . LYS I 1 242 ? 39.737 -23.930 -16.256 1.00 114.95 ? 242 LYS I CA 1 +ATOM 17009 C C . LYS I 1 242 ? 39.607 -25.275 -16.964 1.00 128.79 ? 242 LYS I C 1 +ATOM 17010 O O . LYS I 1 242 ? 38.678 -26.049 -16.692 1.00 109.54 ? 242 LYS I O 1 +ATOM 17011 C CB . LYS I 1 242 ? 38.895 -22.860 -16.949 1.00 109.32 ? 242 LYS I CB 1 +ATOM 17012 C CG . LYS I 1 242 ? 39.144 -21.450 -16.427 1.00 113.38 ? 242 LYS I CG 1 +ATOM 17013 C CD . LYS I 1 242 ? 37.858 -20.774 -15.986 1.00 134.57 ? 242 LYS I CD 1 +ATOM 17014 C CE . LYS I 1 242 ? 38.026 -20.104 -14.629 1.00 144.33 ? 242 LYS I CE 1 +ATOM 17015 N NZ . LYS I 1 242 ? 36.834 -19.300 -14.235 1.00 152.26 ? 242 LYS I NZ 1 +ATOM 17016 N N . ALA I 1 243 ? 40.590 -25.556 -17.825 1.00 154.92 ? 243 ALA I N 1 +ATOM 17017 C CA . ALA I 1 243 ? 40.729 -26.843 -18.504 1.00 168.44 ? 243 ALA I CA 1 +ATOM 17018 C C . ALA I 1 243 ? 40.953 -27.982 -17.516 1.00 179.04 ? 243 ALA I C 1 +ATOM 17019 O O . ALA I 1 243 ? 40.747 -29.153 -17.861 1.00 188.58 ? 243 ALA I O 1 +ATOM 17020 C CB . ALA I 1 243 ? 41.883 -26.791 -19.501 1.00 151.81 ? 243 ALA I CB 1 +ATOM 17021 N N . GLU I 1 244 ? 41.393 -27.651 -16.300 1.00 173.23 ? 244 GLU I N 1 +ATOM 17022 C CA . GLU I 1 244 ? 41.681 -28.680 -15.306 1.00 172.02 ? 244 GLU I CA 1 +ATOM 17023 C C . GLU I 1 244 ? 40.486 -28.981 -14.406 1.00 149.79 ? 244 GLU I C 1 +ATOM 17024 O O . GLU I 1 244 ? 40.640 -29.670 -13.410 1.00 130.86 ? 244 GLU I O 1 +ATOM 17025 C CB . GLU I 1 244 ? 42.894 -28.290 -14.455 1.00 155.45 ? 244 GLU I CB 1 +ATOM 17026 C CG . GLU I 1 244 ? 44.218 -28.389 -15.185 1.00 138.54 ? 244 GLU I CG 1 +ATOM 17027 C CD . GLU I 1 244 ? 45.402 -28.257 -14.250 1.00 142.17 ? 244 GLU I CD 1 +ATOM 17028 O OE1 . GLU I 1 244 ? 45.724 -27.117 -13.843 1.00 137.67 ? 244 GLU I OE1 1 +ATOM 17029 O OE2 . GLU I 1 244 ? 46.040 -29.294 -13.949 1.00 162.68 ? 244 GLU I OE2 1 +ATOM 17030 N N . ARG I 1 245 ? 39.309 -28.469 -14.755 1.00 130.77 ? 245 ARG I N 1 +ATOM 17031 C CA . ARG I 1 245 ? 38.097 -28.810 -14.027 1.00 128.61 ? 245 ARG I CA 1 +ATOM 17032 C C . ARG I 1 245 ? 37.850 -30.317 -13.977 1.00 127.75 ? 245 ARG I C 1 +ATOM 17033 O O . ARG I 1 245 ? 37.319 -30.822 -12.984 1.00 136.78 ? 245 ARG I O 1 +ATOM 17034 C CB . ARG I 1 245 ? 36.872 -28.123 -14.618 1.00 130.32 ? 245 ARG I CB 1 +ATOM 17035 C CG . ARG I 1 245 ? 35.608 -28.300 -13.774 1.00 141.13 ? 245 ARG I CG 1 +ATOM 17036 C CD . ARG I 1 245 ? 34.401 -27.520 -14.316 1.00 162.13 ? 245 ARG I CD 1 +ATOM 17037 N NE . ARG I 1 245 ? 34.239 -26.244 -13.613 1.00 203.38 ? 245 ARG I NE 1 +ATOM 17038 C CZ . ARG I 1 245 ? 33.815 -26.115 -12.355 1.00 195.04 ? 245 ARG I CZ 1 +ATOM 17039 N NH1 . ARG I 1 245 ? 33.527 -27.181 -11.634 1.00 174.75 ? 245 ARG I NH1 1 +ATOM 17040 N NH2 . ARG I 1 245 ? 33.683 -24.911 -11.811 1.00 193.17 ? 245 ARG I NH2 1 +ATOM 17041 N N . GLN I 1 246 ? 38.157 -31.021 -15.065 1.00 130.75 ? 246 GLN I N 1 +ATOM 17042 C CA . GLN I 1 246 ? 37.845 -32.453 -15.148 1.00 146.29 ? 246 GLN I CA 1 +ATOM 17043 C C . GLN I 1 246 ? 39.018 -33.297 -14.673 1.00 134.48 ? 246 GLN I C 1 +ATOM 17044 O O . GLN I 1 246 ? 39.144 -34.465 -15.051 1.00 150.16 ? 246 GLN I O 1 +ATOM 17045 C CB . GLN I 1 246 ? 37.421 -32.858 -16.573 1.00 156.62 ? 246 GLN I CB 1 +ATOM 17046 C CG . GLN I 1 246 ? 36.045 -32.362 -16.991 1.00 156.97 ? 246 GLN I CG 1 +ATOM 17047 C CD . GLN I 1 246 ? 36.046 -30.886 -17.324 1.00 186.07 ? 246 GLN I CD 1 +ATOM 17048 O OE1 . GLN I 1 246 ? 36.937 -30.396 -18.028 1.00 173.00 ? 246 GLN I OE1 1 +ATOM 17049 N NE2 . GLN I 1 246 ? 35.034 -30.169 -16.842 1.00 204.70 ? 246 GLN I NE2 1 +ATOM 17050 N N . ASN I 1 247 ? 39.892 -32.683 -13.880 1.00 116.67 ? 247 ASN I N 1 +ATOM 17051 C CA . ASN I 1 247 ? 40.964 -33.396 -13.173 1.00 126.72 ? 247 ASN I CA 1 +ATOM 17052 C C . ASN I 1 247 ? 40.458 -34.699 -12.556 1.00 107.26 ? 247 ASN I C 1 +ATOM 17053 O O . ASN I 1 247 ? 39.352 -34.738 -12.014 1.00 128.97 ? 247 ASN I O 1 +ATOM 17054 C CB . ASN I 1 247 ? 41.508 -32.496 -12.068 1.00 136.63 ? 247 ASN I CB 1 +ATOM 17055 C CG . ASN I 1 247 ? 42.926 -32.826 -11.688 1.00 154.97 ? 247 ASN I CG 1 +ATOM 17056 O OD1 . ASN I 1 247 ? 43.181 -33.382 -10.612 1.00 179.25 ? 247 ASN I OD1 1 +ATOM 17057 N ND2 . ASN I 1 247 ? 43.862 -32.496 -12.573 1.00 155.77 ? 247 ASN I ND2 1 +ATOM 17058 N N . ASP I 1 248 ? 41.255 -35.762 -12.659 1.00 106.02 ? 248 ASP I N 1 +ATOM 17059 C CA . ASP I 1 248 ? 40.852 -37.100 -12.181 1.00 144.22 ? 248 ASP I CA 1 +ATOM 17060 C C . ASP I 1 248 ? 40.390 -37.057 -10.724 1.00 166.30 ? 248 ASP I C 1 +ATOM 17061 O O . ASP I 1 248 ? 39.356 -37.634 -10.354 1.00 179.65 ? 248 ASP I O 1 +ATOM 17062 C CB . ASP I 1 248 ? 42.024 -38.088 -12.289 1.00 156.22 ? 248 ASP I CB 1 +ATOM 17063 C CG . ASP I 1 248 ? 42.341 -38.482 -13.724 1.00 157.49 ? 248 ASP I CG 1 +ATOM 17064 O OD1 . ASP I 1 248 ? 41.406 -38.661 -14.524 1.00 133.56 ? 248 ASP I OD1 1 +ATOM 17065 O OD2 . ASP I 1 248 ? 43.537 -38.638 -14.039 1.00 168.44 ? 248 ASP I OD2 1 +ATOM 17066 N N . ILE I 1 249 ? 41.175 -36.369 -9.901 1.00 170.49 ? 249 ILE I N 1 +ATOM 17067 C CA . ILE I 1 249 ? 40.915 -36.281 -8.472 1.00 142.34 ? 249 ILE I CA 1 +ATOM 17068 C C . ILE I 1 249 ? 39.619 -35.498 -8.227 1.00 122.00 ? 249 ILE I C 1 +ATOM 17069 O O . ILE I 1 249 ? 38.728 -35.956 -7.505 1.00 132.05 ? 249 ILE I O 1 +ATOM 17070 C CB . ILE I 1 249 ? 42.103 -35.609 -7.747 1.00 133.66 ? 249 ILE I CB 1 +ATOM 17071 C CG1 . ILE I 1 249 ? 43.374 -36.455 -7.904 1.00 124.05 ? 249 ILE I CG1 1 +ATOM 17072 C CG2 . ILE I 1 249 ? 41.791 -35.432 -6.277 1.00 138.91 ? 249 ILE I CG2 1 +ATOM 17073 C CD1 . ILE I 1 249 ? 44.657 -35.686 -7.669 1.00 117.73 ? 249 ILE I CD1 1 +ATOM 17074 N N . LEU I 1 250 ? 39.511 -34.328 -8.855 1.00 109.10 ? 250 LEU I N 1 +ATOM 17075 C CA . LEU I 1 250 ? 38.348 -33.453 -8.676 1.00 103.39 ? 250 LEU I CA 1 +ATOM 17076 C C . LEU I 1 250 ? 37.030 -34.101 -9.093 1.00 108.27 ? 250 LEU I C 1 +ATOM 17077 O O . LEU I 1 250 ? 36.012 -33.927 -8.424 1.00 136.16 ? 250 LEU I O 1 +ATOM 17078 C CB . LEU I 1 250 ? 38.534 -32.154 -9.449 1.00 103.25 ? 250 LEU I CB 1 +ATOM 17079 C CG . LEU I 1 250 ? 39.433 -31.112 -8.773 1.00 102.94 ? 250 LEU I CG 1 +ATOM 17080 C CD1 . LEU I 1 250 ? 39.793 -29.980 -9.721 1.00 106.33 ? 250 LEU I CD1 1 +ATOM 17081 C CD2 . LEU I 1 250 ? 38.744 -30.557 -7.546 1.00 110.01 ? 250 LEU I CD2 1 +ATOM 17082 N N . VAL I 1 251 ? 37.060 -34.878 -10.170 1.00 117.00 ? 251 VAL I N 1 +ATOM 17083 C CA . VAL I 1 251 ? 35.869 -35.604 -10.613 1.00 121.83 ? 251 VAL I CA 1 +ATOM 17084 C C . VAL I 1 251 ? 35.582 -36.834 -9.741 1.00 134.15 ? 251 VAL I C 1 +ATOM 17085 O O . VAL I 1 251 ? 34.436 -37.298 -9.657 1.00 196.37 ? 251 VAL I O 1 +ATOM 17086 C CB . VAL I 1 251 ? 35.961 -36.032 -12.095 1.00 125.86 ? 251 VAL I CB 1 +ATOM 17087 C CG1 . VAL I 1 251 ? 36.256 -34.824 -12.974 1.00 113.10 ? 251 VAL I CG1 1 +ATOM 17088 C CG2 . VAL I 1 251 ? 37.001 -37.138 -12.301 1.00 129.78 ? 251 VAL I CG2 1 +ATOM 17089 N N . LYS I 1 252 ? 36.621 -37.376 -9.111 1.00 117.65 ? 252 LYS I N 1 +ATOM 17090 C CA . LYS I 1 252 ? 36.455 -38.499 -8.188 1.00 113.82 ? 252 LYS I CA 1 +ATOM 17091 C C . LYS I 1 252 ? 35.666 -38.054 -6.936 1.00 107.93 ? 252 LYS I C 1 +ATOM 17092 O O . LYS I 1 252 ? 34.714 -38.712 -6.521 1.00 83.06 ? 252 LYS I O 1 +ATOM 17093 C CB . LYS I 1 252 ? 37.832 -39.054 -7.824 1.00 115.98 ? 252 LYS I CB 1 +ATOM 17094 C CG . LYS I 1 252 ? 37.826 -40.207 -6.835 1.00 121.04 ? 252 LYS I CG 1 +ATOM 17095 C CD . LYS I 1 252 ? 39.261 -40.639 -6.534 1.00 133.99 ? 252 LYS I CD 1 +ATOM 17096 C CE . LYS I 1 252 ? 39.506 -40.803 -5.041 1.00 141.96 ? 252 LYS I CE 1 +ATOM 17097 N NZ . LYS I 1 252 ? 40.948 -40.970 -4.698 1.00 127.72 ? 252 LYS I NZ 1 +ATOM 17098 N N . TYR I 1 253 ? 36.037 -36.897 -6.386 1.00 123.42 ? 253 TYR I N 1 +ATOM 17099 C CA . TYR I 1 253 ? 35.391 -36.352 -5.174 1.00 101.46 ? 253 TYR I CA 1 +ATOM 17100 C C . TYR I 1 253 ? 34.063 -35.712 -5.519 1.00 88.80 ? 253 TYR I C 1 +ATOM 17101 O O . TYR I 1 253 ? 33.130 -35.743 -4.728 1.00 102.11 ? 253 TYR I O 1 +ATOM 17102 C CB . TYR I 1 253 ? 36.315 -35.343 -4.456 1.00 88.75 ? 253 TYR I CB 1 +ATOM 17103 C CG . TYR I 1 253 ? 37.483 -36.008 -3.749 1.00 91.15 ? 253 TYR I CG 1 +ATOM 17104 C CD1 . TYR I 1 253 ? 37.332 -36.578 -2.506 1.00 83.25 ? 253 TYR I CD1 1 +ATOM 17105 C CD2 . TYR I 1 253 ? 38.704 -36.187 -4.396 1.00 114.71 ? 253 TYR I CD2 1 +ATOM 17106 C CE1 . TYR I 1 253 ? 38.374 -37.265 -1.906 1.00 96.71 ? 253 TYR I CE1 1 +ATOM 17107 C CE2 . TYR I 1 253 ? 39.745 -36.890 -3.802 1.00 112.48 ? 253 TYR I CE2 1 +ATOM 17108 C CZ . TYR I 1 253 ? 39.570 -37.420 -2.549 1.00 95.55 ? 253 TYR I CZ 1 +ATOM 17109 O OH . TYR I 1 253 ? 40.611 -38.109 -1.940 1.00 111.30 ? 253 TYR I OH 1 +ATOM 17110 N N . ARG I 1 254 ? 33.982 -35.138 -6.712 1.00 94.52 ? 254 ARG I N 1 +ATOM 17111 C CA . ARG I 1 254 ? 32.709 -34.686 -7.257 1.00 95.08 ? 254 ARG I CA 1 +ATOM 17112 C C . ARG I 1 254 ? 31.722 -35.855 -7.306 1.00 83.68 ? 254 ARG I C 1 +ATOM 17113 O O . ARG I 1 254 ? 30.530 -35.689 -7.040 1.00 81.87 ? 254 ARG I O 1 +ATOM 17114 C CB . ARG I 1 254 ? 32.899 -34.095 -8.667 1.00 116.65 ? 254 ARG I CB 1 +ATOM 17115 C CG . ARG I 1 254 ? 31.633 -33.490 -9.250 1.00 121.63 ? 254 ARG I CG 1 +ATOM 17116 C CD . ARG I 1 254 ? 31.907 -32.562 -10.419 1.00 123.87 ? 254 ARG I CD 1 +ATOM 17117 N NE . ARG I 1 254 ? 32.649 -31.368 -10.035 1.00 112.80 ? 254 ARG I NE 1 +ATOM 17118 C CZ . ARG I 1 254 ? 33.922 -31.132 -10.329 1.00 135.42 ? 254 ARG I CZ 1 +ATOM 17119 N NH1 . ARG I 1 254 ? 34.645 -32.015 -11.011 1.00 136.13 ? 254 ARG I NH1 1 +ATOM 17120 N NH2 . ARG I 1 254 ? 34.485 -29.988 -9.943 1.00 147.60 ? 254 ARG I NH2 1 +ATOM 17121 N N . HIS I 1 255 ? 32.218 -37.026 -7.691 1.00 90.43 ? 255 HIS I N 1 +ATOM 17122 C CA . HIS I 1 255 ? 31.377 -38.217 -7.832 1.00 120.70 ? 255 HIS I CA 1 +ATOM 17123 C C . HIS I 1 255 ? 30.896 -38.721 -6.482 1.00 117.67 ? 255 HIS I C 1 +ATOM 17124 O O . HIS I 1 255 ? 29.800 -39.266 -6.375 1.00 135.35 ? 255 HIS I O 1 +ATOM 17125 C CB . HIS I 1 255 ? 32.123 -39.333 -8.598 1.00 150.00 ? 255 HIS I CB 1 +ATOM 17126 C CG . HIS I 1 255 ? 31.623 -39.551 -9.992 1.00 159.25 ? 255 HIS I CG 1 +ATOM 17127 N ND1 . HIS I 1 255 ? 31.914 -38.690 -11.030 1.00 160.48 ? 255 HIS I ND1 1 +ATOM 17128 C CD2 . HIS I 1 255 ? 30.862 -40.538 -10.521 1.00 163.42 ? 255 HIS I CD2 1 +ATOM 17129 C CE1 . HIS I 1 255 ? 31.354 -39.139 -12.138 1.00 175.32 ? 255 HIS I CE1 1 +ATOM 17130 N NE2 . HIS I 1 255 ? 30.707 -40.257 -11.856 1.00 183.15 ? 255 HIS I NE2 1 +ATOM 17131 N N . MET I 1 256 ? 31.735 -38.589 -5.459 1.00 129.27 ? 256 MET I N 1 +ATOM 17132 C CA . MET I 1 256 ? 31.356 -39.066 -4.124 1.00 132.17 ? 256 MET I CA 1 +ATOM 17133 C C . MET I 1 256 ? 30.221 -38.218 -3.532 1.00 131.49 ? 256 MET I C 1 +ATOM 17134 O O . MET I 1 256 ? 29.461 -38.701 -2.695 1.00 123.86 ? 256 MET I O 1 +ATOM 17135 C CB . MET I 1 256 ? 32.579 -39.102 -3.199 1.00 134.65 ? 256 MET I CB 1 +ATOM 17136 C CG . MET I 1 256 ? 33.763 -39.899 -3.761 1.00 132.73 ? 256 MET I CG 1 +ATOM 17137 S SD . MET I 1 256 ? 35.000 -40.435 -2.562 1.00 106.72 ? 256 MET I SD 1 +ATOM 17138 C CE . MET I 1 256 ? 34.054 -41.664 -1.639 1.00 89.83 ? 256 MET I CE 1 +ATOM 17139 N N . SER I 1 257 ? 30.070 -36.988 -4.036 1.00 145.82 ? 257 SER I N 1 +ATOM 17140 C CA . SER I 1 257 ? 28.958 -36.090 -3.659 1.00 124.58 ? 257 SER I CA 1 +ATOM 17141 C C . SER I 1 257 ? 27.635 -36.446 -4.341 1.00 98.41 ? 257 SER I C 1 +ATOM 17142 O O . SER I 1 257 ? 26.904 -37.294 -3.849 1.00 74.00 ? 257 SER I O 1 +ATOM 17143 C CB . SER I 1 257 ? 29.305 -34.632 -3.998 1.00 116.88 ? 257 SER I CB 1 +ATOM 17144 O OG . SER I 1 257 ? 30.644 -34.318 -3.648 1.00 103.50 ? 257 SER I OG 1 +ATOM 17145 N N . LEU J 1 2 ? 24.473 55.453 3.734 1.00 129.33 ? 2 LEU J N 1 +ATOM 17146 C CA . LEU J 1 2 ? 25.669 55.301 4.626 1.00 126.24 ? 2 LEU J CA 1 +ATOM 17147 C C . LEU J 1 2 ? 25.224 55.025 6.078 1.00 140.10 ? 2 LEU J C 1 +ATOM 17148 O O . LEU J 1 2 ? 25.364 55.877 6.989 1.00 113.69 ? 2 LEU J O 1 +ATOM 17149 C CB . LEU J 1 2 ? 26.594 56.529 4.545 1.00 122.00 ? 2 LEU J CB 1 +ATOM 17150 C CG . LEU J 1 2 ? 27.255 56.881 3.186 1.00 122.32 ? 2 LEU J CG 1 +ATOM 17151 C CD1 . LEU J 1 2 ? 28.094 58.150 3.349 1.00 100.48 ? 2 LEU J CD1 1 +ATOM 17152 C CD2 . LEU J 1 2 ? 28.093 55.753 2.555 1.00 94.36 ? 2 LEU J CD2 1 +ATOM 17153 N N . THR J 1 3 ? 24.566 53.868 6.228 1.00 177.08 ? 3 THR J N 1 +ATOM 17154 C CA . THR J 1 3 ? 24.374 53.185 7.520 1.00 160.32 ? 3 THR J CA 1 +ATOM 17155 C C . THR J 1 3 ? 24.543 51.662 7.354 1.00 134.85 ? 3 THR J C 1 +ATOM 17156 O O . THR J 1 3 ? 24.488 50.910 8.325 1.00 113.79 ? 3 THR J O 1 +ATOM 17157 C CB . THR J 1 3 ? 22.979 53.450 8.132 1.00 130.04 ? 3 THR J CB 1 +ATOM 17158 O OG1 . THR J 1 3 ? 21.976 52.793 7.345 1.00 142.83 ? 3 THR J OG1 1 +ATOM 17159 C CG2 . THR J 1 3 ? 22.702 54.959 8.242 1.00 108.13 ? 3 THR J CG2 1 +ATOM 17160 N N . ALA J 1 4 ? 24.722 51.219 6.113 1.00 117.83 ? 4 ALA J N 1 +ATOM 17161 C CA . ALA J 1 4 ? 25.355 49.936 5.852 1.00 112.66 ? 4 ALA J CA 1 +ATOM 17162 C C . ALA J 1 4 ? 26.866 50.073 6.115 1.00 107.12 ? 4 ALA J C 1 +ATOM 17163 O O . ALA J 1 4 ? 27.326 51.108 6.584 1.00 92.31 ? 4 ALA J O 1 +ATOM 17164 C CB . ALA J 1 4 ? 25.083 49.485 4.424 1.00 134.42 ? 4 ALA J CB 1 +ATOM 17165 N N . PRO J 1 5 ? 27.651 49.012 5.886 1.00 128.56 ? 5 PRO J N 1 +ATOM 17166 C CA . PRO J 1 5 ? 28.944 49.123 6.554 1.00 141.72 ? 5 PRO J CA 1 +ATOM 17167 C C . PRO J 1 5 ? 29.949 49.918 5.726 1.00 136.00 ? 5 PRO J C 1 +ATOM 17168 O O . PRO J 1 5 ? 29.670 50.235 4.569 1.00 77.56 ? 5 PRO J O 1 +ATOM 17169 C CB . PRO J 1 5 ? 29.392 47.669 6.689 1.00 150.47 ? 5 PRO J CB 1 +ATOM 17170 C CG . PRO J 1 5 ? 28.703 46.933 5.574 1.00 157.57 ? 5 PRO J CG 1 +ATOM 17171 C CD . PRO J 1 5 ? 27.508 47.744 5.146 1.00 143.67 ? 5 PRO J CD 1 +ATOM 17172 N N . PRO J 1 6 ? 31.098 50.260 6.333 1.00 115.76 ? 6 PRO J N 1 +ATOM 17173 C CA . PRO J 1 6 ? 32.248 50.765 5.582 1.00 107.48 ? 6 PRO J CA 1 +ATOM 17174 C C . PRO J 1 6 ? 33.077 49.654 4.969 1.00 103.34 ? 6 PRO J C 1 +ATOM 17175 O O . PRO J 1 6 ? 33.102 48.544 5.488 1.00 102.60 ? 6 PRO J O 1 +ATOM 17176 C CB . PRO J 1 6 ? 33.062 51.524 6.629 1.00 119.53 ? 6 PRO J CB 1 +ATOM 17177 C CG . PRO J 1 6 ? 32.590 51.049 7.957 1.00 113.31 ? 6 PRO J CG 1 +ATOM 17178 C CD . PRO J 1 6 ? 31.260 50.378 7.793 1.00 97.56 ? 6 PRO J CD 1 +ATOM 17179 N N . LYS J 1 7 ? 33.741 49.934 3.853 1.00 114.07 ? 7 LYS J N 1 +ATOM 17180 C CA . LYS J 1 7 ? 34.564 48.912 3.188 1.00 133.21 ? 7 LYS J CA 1 +ATOM 17181 C C . LYS J 1 7 ? 36.037 49.008 3.574 1.00 137.50 ? 7 LYS J C 1 +ATOM 17182 O O . LYS J 1 7 ? 36.471 49.975 4.213 1.00 77.01 ? 7 LYS J O 1 +ATOM 17183 C CB . LYS J 1 7 ? 34.427 48.973 1.668 1.00 125.33 ? 7 LYS J CB 1 +ATOM 17184 C CG . LYS J 1 7 ? 33.069 48.577 1.149 1.00 128.22 ? 7 LYS J CG 1 +ATOM 17185 C CD . LYS J 1 7 ? 32.226 49.777 0.728 1.00 147.09 ? 7 LYS J CD 1 +ATOM 17186 C CE . LYS J 1 7 ? 31.023 49.324 -0.083 1.00 165.54 ? 7 LYS J CE 1 +ATOM 17187 N NZ . LYS J 1 7 ? 29.869 50.252 0.054 1.00 168.32 ? 7 LYS J NZ 1 +ATOM 17188 N N . GLU J 1 8 ? 36.794 47.975 3.199 1.00 171.47 ? 8 GLU J N 1 +ATOM 17189 C CA . GLU J 1 8 ? 38.153 47.782 3.714 1.00 182.38 ? 8 GLU J CA 1 +ATOM 17190 C C . GLU J 1 8 ? 39.158 48.831 3.207 1.00 151.75 ? 8 GLU J C 1 +ATOM 17191 O O . GLU J 1 8 ? 39.363 48.974 2.019 1.00 153.43 ? 8 GLU J O 1 +ATOM 17192 C CB . GLU J 1 8 ? 38.637 46.357 3.460 1.00 191.75 ? 8 GLU J CB 1 +ATOM 17193 C CG . GLU J 1 8 ? 38.705 45.523 4.774 1.00 209.11 ? 8 GLU J CG 1 +ATOM 17194 C CD . GLU J 1 8 ? 37.712 44.357 4.861 1.00 185.81 ? 8 GLU J CD 1 +ATOM 17195 O OE1 . GLU J 1 8 ? 36.540 44.582 4.471 1.00 209.55 ? 8 GLU J OE1 1 +ATOM 17196 O OE2 . GLU J 1 8 ? 38.076 43.262 5.404 1.00 99.10 ? 8 GLU J OE2 1 +ATOM 17197 N N . ALA J 1 9 ? 39.694 49.626 4.128 1.00 125.21 ? 9 ALA J N 1 +ATOM 17198 C CA . ALA J 1 9 ? 40.728 50.607 3.833 1.00 90.99 ? 9 ALA J CA 1 +ATOM 17199 C C . ALA J 1 9 ? 42.116 50.028 4.171 1.00 92.93 ? 9 ALA J C 1 +ATOM 17200 O O . ALA J 1 9 ? 42.428 49.769 5.334 1.00 89.80 ? 9 ALA J O 1 +ATOM 17201 C CB . ALA J 1 9 ? 40.474 51.862 4.642 1.00 79.94 ? 9 ALA J CB 1 +ATOM 17202 N N . ALA J 1 10 ? 42.921 49.803 3.138 1.00 86.70 ? 10 ALA J N 1 +ATOM 17203 C CA . ALA J 1 10 ? 44.216 49.099 3.221 1.00 89.23 ? 10 ALA J CA 1 +ATOM 17204 C C . ALA J 1 10 ? 44.024 47.594 3.110 1.00 95.50 ? 10 ALA J C 1 +ATOM 17205 O O . ALA J 1 10 ? 42.940 47.074 3.373 1.00 99.32 ? 10 ALA J O 1 +ATOM 17206 C CB . ALA J 1 10 ? 45.012 49.470 4.474 1.00 77.21 ? 10 ALA J CB 1 +ATOM 17207 N N . ARG J 1 11 ? 45.080 46.904 2.678 1.00 106.96 ? 11 ARG J N 1 +ATOM 17208 C CA . ARG J 1 11 ? 44.979 45.509 2.219 1.00 118.01 ? 11 ARG J CA 1 +ATOM 17209 C C . ARG J 1 11 ? 45.594 44.546 3.222 1.00 89.07 ? 11 ARG J C 1 +ATOM 17210 O O . ARG J 1 11 ? 46.556 44.888 3.906 1.00 117.49 ? 11 ARG J O 1 +ATOM 17211 C CB . ARG J 1 11 ? 45.698 45.340 0.864 1.00 141.37 ? 11 ARG J CB 1 +ATOM 17212 C CG . ARG J 1 11 ? 47.213 45.497 0.921 1.00 158.80 ? 11 ARG J CG 1 +ATOM 17213 C CD . ARG J 1 11 ? 47.786 46.004 -0.404 1.00 175.63 ? 11 ARG J CD 1 +ATOM 17214 N NE . ARG J 1 11 ? 48.338 47.357 -0.282 1.00 187.16 ? 11 ARG J NE 1 +ATOM 17215 C CZ . ARG J 1 11 ? 48.946 48.010 -1.268 1.00 195.23 ? 11 ARG J CZ 1 +ATOM 17216 N NH1 . ARG J 1 11 ? 49.089 47.429 -2.451 1.00 235.85 ? 11 ARG J NH1 1 +ATOM 17217 N NH2 . ARG J 1 11 ? 49.416 49.238 -1.077 1.00 174.08 ? 11 ARG J NH2 1 +ATOM 17218 N N . PRO J 1 12 ? 45.081 43.321 3.285 1.00 64.87 ? 12 PRO J N 1 +ATOM 17219 C CA . PRO J 1 12 ? 45.880 42.301 3.927 1.00 80.46 ? 12 PRO J CA 1 +ATOM 17220 C C . PRO J 1 12 ? 47.216 42.053 3.205 1.00 83.11 ? 12 PRO J C 1 +ATOM 17221 O O . PRO J 1 12 ? 47.237 41.555 2.091 1.00 78.33 ? 12 PRO J O 1 +ATOM 17222 C CB . PRO J 1 12 ? 44.977 41.033 3.874 1.00 76.28 ? 12 PRO J CB 1 +ATOM 17223 C CG . PRO J 1 12 ? 43.646 41.508 3.439 1.00 71.42 ? 12 PRO J CG 1 +ATOM 17224 C CD . PRO J 1 12 ? 43.908 42.745 2.630 1.00 71.43 ? 12 PRO J CD 1 +ATOM 17225 N N . THR J 1 13 ? 48.315 42.364 3.880 1.00 97.18 ? 13 THR J N 1 +ATOM 17226 C CA . THR J 1 13 ? 49.634 41.881 3.496 1.00 116.67 ? 13 THR J CA 1 +ATOM 17227 C C . THR J 1 13 ? 50.028 40.626 4.299 1.00 105.17 ? 13 THR J C 1 +ATOM 17228 O O . THR J 1 13 ? 49.485 40.396 5.380 1.00 189.00 ? 13 THR J O 1 +ATOM 17229 C CB . THR J 1 13 ? 50.669 42.989 3.742 1.00 127.87 ? 13 THR J CB 1 +ATOM 17230 O OG1 . THR J 1 13 ? 51.918 42.608 3.151 1.00 125.50 ? 13 THR J OG1 1 +ATOM 17231 C CG2 . THR J 1 13 ? 50.854 43.278 5.275 1.00 126.46 ? 13 THR J CG2 1 +ATOM 17232 N N . LEU J 1 14 ? 51.006 39.850 3.846 1.00 82.08 ? 14 LEU J N 1 +ATOM 17233 C CA . LEU J 1 14 ? 51.588 38.848 4.764 1.00 118.54 ? 14 LEU J CA 1 +ATOM 17234 C C . LEU J 1 14 ? 52.503 39.553 5.790 1.00 138.42 ? 14 LEU J C 1 +ATOM 17235 O O . LEU J 1 14 ? 52.851 40.703 5.597 1.00 132.45 ? 14 LEU J O 1 +ATOM 17236 C CB . LEU J 1 14 ? 52.269 37.681 4.049 1.00 99.34 ? 14 LEU J CB 1 +ATOM 17237 C CG . LEU J 1 14 ? 53.334 38.007 3.040 1.00 105.86 ? 14 LEU J CG 1 +ATOM 17238 C CD1 . LEU J 1 14 ? 54.387 36.920 3.020 1.00 94.60 ? 14 LEU J CD1 1 +ATOM 17239 C CD2 . LEU J 1 14 ? 52.682 38.121 1.679 1.00 130.19 ? 14 LEU J CD2 1 +ATOM 17240 N N . MET J 1 15 ? 52.764 38.934 6.942 1.00 151.82 ? 15 MET J N 1 +ATOM 17241 C CA . MET J 1 15 ? 53.107 39.702 8.158 1.00 119.81 ? 15 MET J CA 1 +ATOM 17242 C C . MET J 1 15 ? 54.489 40.343 8.031 1.00 93.43 ? 15 MET J C 1 +ATOM 17243 O O . MET J 1 15 ? 55.472 39.654 7.788 1.00 56.94 ? 15 MET J O 1 +ATOM 17244 C CB . MET J 1 15 ? 53.034 38.836 9.435 1.00 117.28 ? 15 MET J CB 1 +ATOM 17245 C CG . MET J 1 15 ? 52.679 39.629 10.696 1.00 99.67 ? 15 MET J CG 1 +ATOM 17246 S SD . MET J 1 15 ? 53.343 39.132 12.297 1.00 102.14 ? 15 MET J SD 1 +ATOM 17247 C CE . MET J 1 15 ? 54.859 38.205 11.911 1.00 123.00 ? 15 MET J CE 1 +ATOM 17248 N N . PRO J 1 16 ? 54.546 41.681 8.170 1.00 93.48 ? 16 PRO J N 1 +ATOM 17249 C CA . PRO J 1 16 ? 55.741 42.503 7.918 1.00 105.76 ? 16 PRO J CA 1 +ATOM 17250 C C . PRO J 1 16 ? 56.966 42.228 8.797 1.00 106.64 ? 16 PRO J C 1 +ATOM 17251 O O . PRO J 1 16 ? 57.209 42.917 9.799 1.00 139.40 ? 16 PRO J O 1 +ATOM 17252 C CB . PRO J 1 16 ? 55.230 43.932 8.145 1.00 120.26 ? 16 PRO J CB 1 +ATOM 17253 C CG . PRO J 1 16 ? 54.060 43.782 9.050 1.00 108.45 ? 16 PRO J CG 1 +ATOM 17254 C CD . PRO J 1 16 ? 53.409 42.507 8.622 1.00 92.73 ? 16 PRO J CD 1 +ATOM 17255 N N . ARG J 1 17 ? 57.700 41.187 8.449 1.00 107.65 ? 17 ARG J N 1 +ATOM 17256 C CA . ARG J 1 17 ? 58.934 40.864 9.142 1.00 128.97 ? 17 ARG J CA 1 +ATOM 17257 C C . ARG J 1 17 ? 60.061 41.652 8.475 1.00 109.55 ? 17 ARG J C 1 +ATOM 17258 O O . ARG J 1 17 ? 60.044 41.805 7.272 1.00 108.93 ? 17 ARG J O 1 +ATOM 17259 C CB . ARG J 1 17 ? 59.175 39.335 9.098 1.00 143.38 ? 17 ARG J CB 1 +ATOM 17260 C CG . ARG J 1 17 ? 58.513 38.568 10.245 1.00 123.21 ? 17 ARG J CG 1 +ATOM 17261 C CD . ARG J 1 17 ? 58.392 37.085 9.980 1.00 117.69 ? 17 ARG J CD 1 +ATOM 17262 N NE . ARG J 1 17 ? 57.280 36.781 9.093 1.00 118.55 ? 17 ARG J NE 1 +ATOM 17263 C CZ . ARG J 1 17 ? 57.055 35.576 8.579 1.00 143.58 ? 17 ARG J CZ 1 +ATOM 17264 N NH1 . ARG J 1 17 ? 57.856 34.556 8.897 1.00 160.91 ? 17 ARG J NH1 1 +ATOM 17265 N NH2 . ARG J 1 17 ? 56.035 35.372 7.759 1.00 128.72 ? 17 ARG J NH2 1 +ATOM 17266 N N . ALA J 1 18 ? 61.076 42.057 9.236 1.00 107.78 ? 18 ALA J N 1 +ATOM 17267 C CA . ALA J 1 18 ? 62.195 42.813 8.671 1.00 94.97 ? 18 ALA J CA 1 +ATOM 17268 C C . ALA J 1 18 ? 63.538 42.041 8.704 1.00 94.51 ? 18 ALA J C 1 +ATOM 17269 O O . ALA J 1 18 ? 63.693 41.019 8.024 1.00 71.48 ? 18 ALA J O 1 +ATOM 17270 C CB . ALA J 1 18 ? 62.320 44.151 9.365 1.00 88.14 ? 18 ALA J CB 1 +ATOM 17271 N N . GLN J 1 19 ? 64.531 42.589 9.400 1.00 91.02 ? 19 GLN J N 1 +ATOM 17272 C CA . GLN J 1 19 ? 65.926 42.240 9.133 1.00 114.86 ? 19 GLN J CA 1 +ATOM 17273 C C . GLN J 1 19 ? 66.226 40.804 9.574 1.00 109.00 ? 19 GLN J C 1 +ATOM 17274 O O . GLN J 1 19 ? 66.860 40.021 8.847 1.00 108.44 ? 19 GLN J O 1 +ATOM 17275 C CB . GLN J 1 19 ? 66.869 43.232 9.841 1.00 129.52 ? 19 GLN J CB 1 +ATOM 17276 C CG . GLN J 1 19 ? 68.353 43.043 9.525 1.00 137.81 ? 19 GLN J CG 1 +ATOM 17277 C CD . GLN J 1 19 ? 68.633 43.064 8.034 1.00 125.98 ? 19 GLN J CD 1 +ATOM 17278 O OE1 . GLN J 1 19 ? 68.482 44.095 7.378 1.00 134.86 ? 19 GLN J OE1 1 +ATOM 17279 N NE2 . GLN J 1 19 ? 69.033 41.921 7.489 1.00 113.45 ? 19 GLN J NE2 1 +ATOM 17280 N N . SER J 1 20 ? 65.851 40.518 10.815 1.00 86.65 ? 20 SER J N 1 +ATOM 17281 C CA . SER J 1 20 ? 66.001 39.211 11.389 1.00 80.26 ? 20 SER J CA 1 +ATOM 17282 C C . SER J 1 20 ? 65.556 38.172 10.363 1.00 114.59 ? 20 SER J C 1 +ATOM 17283 O O . SER J 1 20 ? 66.240 37.160 10.142 1.00 99.68 ? 20 SER J O 1 +ATOM 17284 C CB . SER J 1 20 ? 65.154 39.145 12.661 1.00 81.83 ? 20 SER J CB 1 +ATOM 17285 O OG . SER J 1 20 ? 65.464 40.218 13.543 1.00 68.50 ? 20 SER J OG 1 +ATOM 17286 N N . TYR J 1 21 ? 64.380 38.400 9.772 1.00 141.89 ? 21 TYR J N 1 +ATOM 17287 C CA . TYR J 1 21 ? 63.800 37.471 8.784 1.00 151.30 ? 21 TYR J CA 1 +ATOM 17288 C C . TYR J 1 21 ? 64.732 37.274 7.599 1.00 122.91 ? 21 TYR J C 1 +ATOM 17289 O O . TYR J 1 21 ? 64.977 36.140 7.166 1.00 69.14 ? 21 TYR J O 1 +ATOM 17290 C CB . TYR J 1 21 ? 62.439 37.997 8.298 1.00 163.91 ? 21 TYR J CB 1 +ATOM 17291 C CG . TYR J 1 21 ? 61.762 37.099 7.280 1.00 163.06 ? 21 TYR J CG 1 +ATOM 17292 C CD1 . TYR J 1 21 ? 61.136 35.920 7.670 1.00 173.91 ? 21 TYR J CD1 1 +ATOM 17293 C CD2 . TYR J 1 21 ? 61.752 37.430 5.937 1.00 170.18 ? 21 TYR J CD2 1 +ATOM 17294 C CE1 . TYR J 1 21 ? 60.531 35.089 6.753 1.00 173.01 ? 21 TYR J CE1 1 +ATOM 17295 C CE2 . TYR J 1 21 ? 61.134 36.602 5.014 1.00 182.32 ? 21 TYR J CE2 1 +ATOM 17296 C CZ . TYR J 1 21 ? 60.515 35.437 5.438 1.00 174.55 ? 21 TYR J CZ 1 +ATOM 17297 O OH . TYR J 1 21 ? 59.922 34.581 4.542 1.00 155.25 ? 21 TYR J OH 1 +ATOM 17298 N N . LYS J 1 22 ? 65.233 38.391 7.076 1.00 124.82 ? 22 LYS J N 1 +ATOM 17299 C CA . LYS J 1 22 ? 66.069 38.375 5.883 1.00 144.27 ? 22 LYS J CA 1 +ATOM 17300 C C . LYS J 1 22 ? 67.348 37.582 6.122 1.00 148.39 ? 22 LYS J C 1 +ATOM 17301 O O . LYS J 1 22 ? 67.799 36.827 5.246 1.00 196.21 ? 22 LYS J O 1 +ATOM 17302 C CB . LYS J 1 22 ? 66.414 39.806 5.445 1.00 123.95 ? 22 LYS J CB 1 +ATOM 17303 C CG . LYS J 1 22 ? 65.416 40.438 4.483 1.00 139.86 ? 22 LYS J CG 1 +ATOM 17304 C CD . LYS J 1 22 ? 65.889 40.391 3.033 1.00 159.14 ? 22 LYS J CD 1 +ATOM 17305 C CE . LYS J 1 22 ? 64.957 40.340 1.907 1.00 172.04 ? 22 LYS J CE 1 +ATOM 17306 N NZ . LYS J 1 22 ? 65.001 41.600 1.136 1.00 153.58 ? 22 LYS J NZ 1 +ATOM 17307 N N . ASP J 1 23 ? 67.921 37.752 7.309 1.00 116.44 ? 23 ASP J N 1 +ATOM 17308 C CA . ASP J 1 23 ? 69.088 36.970 7.717 1.00 128.63 ? 23 ASP J CA 1 +ATOM 17309 C C . ASP J 1 23 ? 68.738 35.490 7.854 1.00 133.87 ? 23 ASP J C 1 +ATOM 17310 O O . ASP J 1 23 ? 69.470 34.614 7.380 1.00 107.71 ? 23 ASP J O 1 +ATOM 17311 C CB . ASP J 1 23 ? 69.619 37.480 9.055 1.00 139.47 ? 23 ASP J CB 1 +ATOM 17312 C CG . ASP J 1 23 ? 70.210 38.854 8.954 1.00 134.77 ? 23 ASP J CG 1 +ATOM 17313 O OD1 . ASP J 1 23 ? 70.919 39.104 7.962 1.00 117.40 ? 23 ASP J OD1 1 +ATOM 17314 O OD2 . ASP J 1 23 ? 69.979 39.669 9.875 1.00 166.55 ? 23 ASP J OD2 1 +ATOM 17315 N N . LEU J 1 24 ? 67.597 35.229 8.490 1.00 144.81 ? 24 LEU J N 1 +ATOM 17316 C CA . LEU J 1 24 ? 67.160 33.866 8.807 1.00 155.10 ? 24 LEU J CA 1 +ATOM 17317 C C . LEU J 1 24 ? 66.886 33.033 7.551 1.00 163.80 ? 24 LEU J C 1 +ATOM 17318 O O . LEU J 1 24 ? 67.149 31.819 7.520 1.00 134.34 ? 24 LEU J O 1 +ATOM 17319 C CB . LEU J 1 24 ? 65.893 33.922 9.678 1.00 150.99 ? 24 LEU J CB 1 +ATOM 17320 C CG . LEU J 1 24 ? 65.273 32.593 10.143 1.00 135.45 ? 24 LEU J CG 1 +ATOM 17321 C CD1 . LEU J 1 24 ? 65.937 32.096 11.419 1.00 146.82 ? 24 LEU J CD1 1 +ATOM 17322 C CD2 . LEU J 1 24 ? 63.781 32.762 10.354 1.00 128.76 ? 24 LEU J CD2 1 +ATOM 17323 N N . THR J 1 25 ? 66.332 33.684 6.528 1.00 172.44 ? 25 THR J N 1 +ATOM 17324 C CA . THR J 1 25 ? 65.979 33.004 5.281 1.00 148.34 ? 25 THR J CA 1 +ATOM 17325 C C . THR J 1 25 ? 67.220 32.671 4.439 1.00 142.70 ? 25 THR J C 1 +ATOM 17326 O O . THR J 1 25 ? 67.361 31.544 3.943 1.00 86.77 ? 25 THR J O 1 +ATOM 17327 C CB . THR J 1 25 ? 64.991 33.847 4.446 1.00 136.69 ? 25 THR J CB 1 +ATOM 17328 O OG1 . THR J 1 25 ? 65.447 35.207 4.380 1.00 146.80 ? 25 THR J OG1 1 +ATOM 17329 C CG2 . THR J 1 25 ? 63.605 33.801 5.067 1.00 108.76 ? 25 THR J CG2 1 +ATOM 17330 N N . HIS J 1 26 ? 68.103 33.661 4.276 1.00 168.50 ? 26 HIS J N 1 +ATOM 17331 C CA . HIS J 1 26 ? 69.295 33.534 3.430 1.00 163.78 ? 26 HIS J CA 1 +ATOM 17332 C C . HIS J 1 26 ? 70.452 32.873 4.205 1.00 129.04 ? 26 HIS J C 1 +ATOM 17333 O O . HIS J 1 26 ? 71.615 33.212 4.022 1.00 124.55 ? 26 HIS J O 1 +ATOM 17334 C CB . HIS J 1 26 ? 69.715 34.918 2.878 1.00 150.49 ? 26 HIS J CB 1 +ATOM 17335 C CG . HIS J 1 26 ? 68.704 35.546 1.962 1.00 157.09 ? 26 HIS J CG 1 +ATOM 17336 N ND1 . HIS J 1 26 ? 67.485 36.019 2.402 1.00 147.19 ? 26 HIS J ND1 1 +ATOM 17337 C CD2 . HIS J 1 26 ? 68.734 35.777 0.626 1.00 173.31 ? 26 HIS J CD2 1 +ATOM 17338 C CE1 . HIS J 1 26 ? 66.797 36.491 1.378 1.00 149.44 ? 26 HIS J CE1 1 +ATOM 17339 N NE2 . HIS J 1 26 ? 67.537 36.366 0.290 1.00 184.97 ? 26 HIS J NE2 1 +ATOM 17340 N N . LEU J 1 27 ? 70.128 31.921 5.068 1.00 106.90 ? 27 LEU J N 1 +ATOM 17341 C CA . LEU J 1 27 ? 71.154 31.153 5.759 1.00 116.69 ? 27 LEU J CA 1 +ATOM 17342 C C . LEU J 1 27 ? 71.558 29.954 4.907 1.00 95.11 ? 27 LEU J C 1 +ATOM 17343 O O . LEU J 1 27 ? 70.696 29.238 4.394 1.00 109.28 ? 27 LEU J O 1 +ATOM 17344 C CB . LEU J 1 27 ? 70.649 30.687 7.140 1.00 139.34 ? 27 LEU J CB 1 +ATOM 17345 C CG . LEU J 1 27 ? 70.858 31.678 8.290 1.00 133.36 ? 27 LEU J CG 1 +ATOM 17346 C CD1 . LEU J 1 27 ? 70.055 31.276 9.509 1.00 135.07 ? 27 LEU J CD1 1 +ATOM 17347 C CD2 . LEU J 1 27 ? 72.336 31.790 8.646 1.00 139.64 ? 27 LEU J CD2 1 +ATOM 17348 N N . PRO J 1 28 ? 72.863 29.683 4.819 1.00 78.29 ? 28 PRO J N 1 +ATOM 17349 C CA . PRO J 1 28 ? 73.361 28.528 4.064 1.00 99.07 ? 28 PRO J CA 1 +ATOM 17350 C C . PRO J 1 28 ? 72.825 27.209 4.581 1.00 96.99 ? 28 PRO J C 1 +ATOM 17351 O O . PRO J 1 28 ? 72.905 26.954 5.764 1.00 104.74 ? 28 PRO J O 1 +ATOM 17352 C CB . PRO J 1 28 ? 74.884 28.590 4.281 1.00 124.35 ? 28 PRO J CB 1 +ATOM 17353 C CG . PRO J 1 28 ? 75.061 29.354 5.546 1.00 108.79 ? 28 PRO J CG 1 +ATOM 17354 C CD . PRO J 1 28 ? 73.939 30.358 5.561 1.00 92.53 ? 28 PRO J CD 1 +ATOM 17355 N N . ALA J 1 29 ? 72.287 26.374 3.694 1.00 139.27 ? 29 ALA J N 1 +ATOM 17356 C CA . ALA J 1 29 ? 71.505 25.196 4.109 1.00 138.53 ? 29 ALA J CA 1 +ATOM 17357 C C . ALA J 1 29 ? 72.396 24.056 4.667 1.00 114.42 ? 29 ALA J C 1 +ATOM 17358 O O . ALA J 1 29 ? 73.563 23.925 4.288 1.00 101.51 ? 29 ALA J O 1 +ATOM 17359 C CB . ALA J 1 29 ? 70.638 24.694 2.953 1.00 129.86 ? 29 ALA J CB 1 +ATOM 17360 N N . PRO J 1 30 ? 71.859 23.277 5.623 1.00 90.75 ? 30 PRO J N 1 +ATOM 17361 C CA . PRO J 1 30 ? 72.569 22.150 6.235 1.00 100.62 ? 30 PRO J CA 1 +ATOM 17362 C C . PRO J 1 30 ? 72.517 20.936 5.331 1.00 89.40 ? 30 PRO J C 1 +ATOM 17363 O O . PRO J 1 30 ? 71.847 20.983 4.288 1.00 67.27 ? 30 PRO J O 1 +ATOM 17364 C CB . PRO J 1 30 ? 71.755 21.870 7.489 1.00 119.88 ? 30 PRO J CB 1 +ATOM 17365 C CG . PRO J 1 30 ? 70.372 22.317 7.148 1.00 116.53 ? 30 PRO J CG 1 +ATOM 17366 C CD . PRO J 1 30 ? 70.518 23.471 6.202 1.00 99.70 ? 30 PRO J CD 1 +ATOM 17367 N N . THR J 1 31 ? 73.192 19.858 5.735 1.00 89.63 ? 31 THR J N 1 +ATOM 17368 C CA . THR J 1 31 ? 73.247 18.635 4.914 1.00 127.72 ? 31 THR J CA 1 +ATOM 17369 C C . THR J 1 31 ? 71.884 17.946 4.814 1.00 146.80 ? 31 THR J C 1 +ATOM 17370 O O . THR J 1 31 ? 71.605 17.240 3.838 1.00 193.89 ? 31 THR J O 1 +ATOM 17371 C CB . THR J 1 31 ? 74.303 17.610 5.410 1.00 115.04 ? 31 THR J CB 1 +ATOM 17372 O OG1 . THR J 1 31 ? 74.115 17.334 6.799 1.00 131.63 ? 31 THR J OG1 1 +ATOM 17373 C CG2 . THR J 1 31 ? 75.713 18.135 5.188 1.00 131.52 ? 31 THR J CG2 1 +ATOM 17374 N N . GLY J 1 32 ? 71.055 18.127 5.835 1.00 140.12 ? 32 GLY J N 1 +ATOM 17375 C CA . GLY J 1 32 ? 69.650 17.726 5.777 1.00 149.56 ? 32 GLY J CA 1 +ATOM 17376 C C . GLY J 1 32 ? 68.876 18.518 6.802 1.00 134.45 ? 32 GLY J C 1 +ATOM 17377 O O . GLY J 1 32 ? 69.476 19.045 7.741 1.00 175.61 ? 32 GLY J O 1 +ATOM 17378 N N . LYS J 1 33 ? 67.579 18.716 6.580 1.00 114.78 ? 33 LYS J N 1 +ATOM 17379 C CA . LYS J 1 33 ? 66.789 19.470 7.551 1.00 106.52 ? 33 LYS J CA 1 +ATOM 17380 C C . LYS J 1 33 ? 66.641 18.658 8.840 1.00 124.96 ? 33 LYS J C 1 +ATOM 17381 O O . LYS J 1 33 ? 66.711 17.423 8.795 1.00 101.46 ? 33 LYS J O 1 +ATOM 17382 C CB . LYS J 1 33 ? 65.425 19.841 7.002 1.00 92.88 ? 33 LYS J CB 1 +ATOM 17383 C CG . LYS J 1 33 ? 65.365 21.187 6.309 1.00 78.32 ? 33 LYS J CG 1 +ATOM 17384 C CD . LYS J 1 33 ? 64.005 21.399 5.658 1.00 90.35 ? 33 LYS J CD 1 +ATOM 17385 C CE . LYS J 1 33 ? 64.097 22.359 4.493 1.00 104.57 ? 33 LYS J CE 1 +ATOM 17386 N NZ . LYS J 1 33 ? 62.819 22.454 3.744 1.00 97.89 ? 33 LYS J NZ 1 +ATOM 17387 N N . ILE J 1 34 ? 66.498 19.348 9.979 1.00 127.03 ? 34 ILE J N 1 +ATOM 17388 C CA . ILE J 1 34 ? 66.461 18.682 11.275 1.00 126.34 ? 34 ILE J CA 1 +ATOM 17389 C C . ILE J 1 34 ? 65.019 18.735 11.789 1.00 131.29 ? 34 ILE J C 1 +ATOM 17390 O O . ILE J 1 34 ? 64.285 19.671 11.480 1.00 86.57 ? 34 ILE J O 1 +ATOM 17391 C CB . ILE J 1 34 ? 67.491 19.290 12.263 1.00 132.89 ? 34 ILE J CB 1 +ATOM 17392 C CG1 . ILE J 1 34 ? 68.920 19.004 11.786 1.00 133.40 ? 34 ILE J CG1 1 +ATOM 17393 C CG2 . ILE J 1 34 ? 67.363 18.700 13.659 1.00 144.90 ? 34 ILE J CG2 1 +ATOM 17394 C CD1 . ILE J 1 34 ? 69.708 20.261 11.476 1.00 145.76 ? 34 ILE J CD1 1 +ATOM 17395 N N . PHE J 1 35 ? 64.586 17.624 12.405 1.00 141.71 ? 35 PHE J N 1 +ATOM 17396 C CA . PHE J 1 35 ? 63.214 17.440 12.926 1.00 86.38 ? 35 PHE J CA 1 +ATOM 17397 C C . PHE J 1 35 ? 63.079 18.047 14.305 1.00 73.15 ? 35 PHE J C 1 +ATOM 17398 O O . PHE J 1 35 ? 63.901 17.725 15.197 1.00 72.52 ? 35 PHE J O 1 +ATOM 17399 C CB . PHE J 1 35 ? 62.929 15.963 13.079 1.00 72.23 ? 35 PHE J CB 1 +ATOM 17400 C CG . PHE J 1 35 ? 62.390 15.312 11.867 1.00 70.45 ? 35 PHE J CG 1 +ATOM 17401 C CD1 . PHE J 1 35 ? 61.407 15.928 11.101 1.00 71.28 ? 35 PHE J CD1 1 +ATOM 17402 C CD2 . PHE J 1 35 ? 62.806 14.031 11.537 1.00 70.91 ? 35 PHE J CD2 1 +ATOM 17403 C CE1 . PHE J 1 35 ? 60.916 15.311 9.971 1.00 87.14 ? 35 PHE J CE1 1 +ATOM 17404 C CE2 . PHE J 1 35 ? 62.309 13.400 10.420 1.00 82.75 ? 35 PHE J CE2 1 +ATOM 17405 C CZ . PHE J 1 35 ? 61.366 14.041 9.629 1.00 99.87 ? 35 PHE J CZ 1 +ATOM 17406 N N . VAL J 1 36 ? 62.116 18.951 14.482 1.00 45.08 ? 36 VAL J N 1 +ATOM 17407 C CA . VAL J 1 36 ? 62.088 19.706 15.712 1.00 56.54 ? 36 VAL J CA 1 +ATOM 17408 C C . VAL J 1 36 ? 60.711 19.781 16.280 1.00 66.79 ? 36 VAL J C 1 +ATOM 17409 O O . VAL J 1 36 ? 59.728 19.726 15.558 1.00 91.96 ? 36 VAL J O 1 +ATOM 17410 C CB . VAL J 1 36 ? 62.601 21.137 15.538 1.00 76.17 ? 36 VAL J CB 1 +ATOM 17411 C CG1 . VAL J 1 36 ? 61.583 22.008 14.811 1.00 69.24 ? 36 VAL J CG1 1 +ATOM 17412 C CG2 . VAL J 1 36 ? 62.947 21.748 16.896 1.00 102.40 ? 36 VAL J CG2 1 +ATOM 17413 N N . SER J 1 37 ? 60.629 19.867 17.605 1.00 75.12 ? 37 SER J N 1 +ATOM 17414 C CA . SER J 1 37 ? 59.342 19.916 18.281 1.00 74.07 ? 37 SER J CA 1 +ATOM 17415 C C . SER J 1 37 ? 59.289 21.185 19.077 1.00 61.50 ? 37 SER J C 1 +ATOM 17416 O O . SER J 1 37 ? 60.181 21.436 19.881 1.00 44.85 ? 37 SER J O 1 +ATOM 17417 C CB . SER J 1 37 ? 59.190 18.704 19.218 1.00 83.89 ? 37 SER J CB 1 +ATOM 17418 O OG . SER J 1 37 ? 58.930 17.494 18.510 1.00 64.84 ? 37 SER J OG 1 +ATOM 17419 N N . VAL J 1 38 ? 58.200 21.924 18.956 1.00 60.27 ? 38 VAL J N 1 +ATOM 17420 C CA . VAL J 1 38 ? 57.934 22.948 19.956 1.00 96.59 ? 38 VAL J CA 1 +ATOM 17421 C C . VAL J 1 38 ? 56.600 22.673 20.656 1.00 109.42 ? 38 VAL J C 1 +ATOM 17422 O O . VAL J 1 38 ? 55.551 22.693 20.011 1.00 105.50 ? 38 VAL J O 1 +ATOM 17423 C CB . VAL J 1 38 ? 57.875 24.347 19.334 1.00 108.61 ? 38 VAL J CB 1 +ATOM 17424 C CG1 . VAL J 1 38 ? 57.555 25.394 20.391 1.00 124.00 ? 38 VAL J CG1 1 +ATOM 17425 C CG2 . VAL J 1 38 ? 59.186 24.688 18.640 1.00 110.64 ? 38 VAL J CG2 1 +ATOM 17426 N N . TYR J 1 39 ? 56.646 22.496 21.988 1.00 97.07 ? 39 TYR J N 1 +ATOM 17427 C CA . TYR J 1 39 ? 55.449 22.246 22.792 1.00 77.39 ? 39 TYR J CA 1 +ATOM 17428 C C . TYR J 1 39 ? 54.814 23.582 23.278 1.00 77.51 ? 39 TYR J C 1 +ATOM 17429 O O . TYR J 1 39 ? 53.639 23.842 23.049 1.00 56.78 ? 39 TYR J O 1 +ATOM 17430 C CB . TYR J 1 39 ? 55.792 21.299 23.957 1.00 77.81 ? 39 TYR J CB 1 +ATOM 17431 C CG . TYR J 1 39 ? 55.774 19.803 23.582 1.00 76.13 ? 39 TYR J CG 1 +ATOM 17432 C CD1 . TYR J 1 39 ? 56.825 19.212 22.907 1.00 49.17 ? 39 TYR J CD1 1 +ATOM 17433 C CD2 . TYR J 1 39 ? 54.675 18.989 23.931 1.00 104.53 ? 39 TYR J CD2 1 +ATOM 17434 C CE1 . TYR J 1 39 ? 56.794 17.866 22.594 1.00 41.65 ? 39 TYR J CE1 1 +ATOM 17435 C CE2 . TYR J 1 39 ? 54.614 17.641 23.582 1.00 74.66 ? 39 TYR J CE2 1 +ATOM 17436 C CZ . TYR J 1 39 ? 55.687 17.094 22.918 1.00 52.70 ? 39 TYR J CZ 1 +ATOM 17437 O OH . TYR J 1 39 ? 55.578 15.791 22.532 1.00 57.27 ? 39 TYR J OH 1 +ATOM 17438 N N . ASN J 1 40 ? 55.607 24.442 23.905 1.00 79.22 ? 40 ASN J N 1 +ATOM 17439 C CA . ASN J 1 40 ? 55.090 25.708 24.409 1.00 74.78 ? 40 ASN J CA 1 +ATOM 17440 C C . ASN J 1 40 ? 56.172 26.700 24.870 1.00 87.49 ? 40 ASN J C 1 +ATOM 17441 O O . ASN J 1 40 ? 57.122 26.343 25.581 1.00 84.01 ? 40 ASN J O 1 +ATOM 17442 C CB . ASN J 1 40 ? 54.177 25.447 25.583 1.00 93.95 ? 40 ASN J CB 1 +ATOM 17443 C CG . ASN J 1 40 ? 53.265 26.617 25.868 1.00 118.03 ? 40 ASN J CG 1 +ATOM 17444 O OD1 . ASN J 1 40 ? 52.467 27.031 25.027 1.00 140.98 ? 40 ASN J OD1 1 +ATOM 17445 N ND2 . ASN J 1 40 ? 53.361 27.138 27.083 1.00 144.98 ? 40 ASN J ND2 1 +ATOM 17446 N N . ILE J 1 41 ? 56.024 27.950 24.451 1.00 83.34 ? 41 ILE J N 1 +ATOM 17447 C CA . ILE J 1 41 ? 56.850 29.038 24.963 1.00 75.64 ? 41 ILE J CA 1 +ATOM 17448 C C . ILE J 1 41 ? 55.943 30.034 25.679 1.00 88.24 ? 41 ILE J C 1 +ATOM 17449 O O . ILE J 1 41 ? 55.079 30.653 25.048 1.00 126.04 ? 41 ILE J O 1 +ATOM 17450 C CB . ILE J 1 41 ? 57.627 29.757 23.835 1.00 66.00 ? 41 ILE J CB 1 +ATOM 17451 C CG1 . ILE J 1 41 ? 58.895 28.977 23.462 1.00 69.36 ? 41 ILE J CG1 1 +ATOM 17452 C CG2 . ILE J 1 41 ? 58.089 31.123 24.304 1.00 70.39 ? 41 ILE J CG2 1 +ATOM 17453 C CD1 . ILE J 1 41 ? 58.675 27.684 22.721 1.00 70.99 ? 41 ILE J CD1 1 +ATOM 17454 N N . GLN J 1 42 ? 56.142 30.197 26.988 1.00 96.56 ? 42 GLN J N 1 +ATOM 17455 C CA . GLN J 1 42 ? 55.192 30.944 27.837 1.00 87.65 ? 42 GLN J CA 1 +ATOM 17456 C C . GLN J 1 42 ? 55.506 32.411 27.954 1.00 74.37 ? 42 GLN J C 1 +ATOM 17457 O O . GLN J 1 42 ? 56.639 32.843 27.707 1.00 111.94 ? 42 GLN J O 1 +ATOM 17458 C CB . GLN J 1 42 ? 55.165 30.394 29.254 1.00 92.19 ? 42 GLN J CB 1 +ATOM 17459 C CG . GLN J 1 42 ? 54.644 28.973 29.358 1.00 112.68 ? 42 GLN J CG 1 +ATOM 17460 C CD . GLN J 1 42 ? 55.680 28.020 29.927 1.00 120.80 ? 42 GLN J CD 1 +ATOM 17461 O OE1 . GLN J 1 42 ? 55.797 27.874 31.145 1.00 152.77 ? 42 GLN J OE1 1 +ATOM 17462 N NE2 . GLN J 1 42 ? 56.468 27.401 29.050 1.00 112.17 ? 42 GLN J NE2 1 +ATOM 17463 N N . ASP J 1 43 ? 54.475 33.185 28.259 1.00 59.71 ? 43 ASP J N 1 +ATOM 17464 C CA . ASP J 1 43 ? 54.633 34.611 28.548 1.00 65.31 ? 43 ASP J CA 1 +ATOM 17465 C C . ASP J 1 43 ? 55.101 34.822 29.966 1.00 52.53 ? 43 ASP J C 1 +ATOM 17466 O O . ASP J 1 43 ? 54.312 35.269 30.809 1.00 59.06 ? 43 ASP J O 1 +ATOM 17467 C CB . ASP J 1 43 ? 53.285 35.343 28.318 1.00 87.86 ? 43 ASP J CB 1 +ATOM 17468 C CG . ASP J 1 43 ? 53.409 36.879 28.419 1.00 97.73 ? 43 ASP J CG 1 +ATOM 17469 O OD1 . ASP J 1 43 ? 54.337 37.443 27.803 1.00 112.65 ? 43 ASP J OD1 1 +ATOM 17470 O OD2 . ASP J 1 43 ? 52.622 37.523 29.149 1.00 75.26 ? 43 ASP J OD2 1 +ATOM 17471 N N . GLU J 1 44 ? 56.306 34.361 30.273 1.00 56.06 ? 44 GLU J N 1 +ATOM 17472 C CA . GLU J 1 44 ? 56.792 34.312 31.668 1.00 74.15 ? 44 GLU J CA 1 +ATOM 17473 C C . GLU J 1 44 ? 57.079 35.735 32.176 1.00 80.07 ? 44 GLU J C 1 +ATOM 17474 O O . GLU J 1 44 ? 57.752 35.919 33.206 1.00 66.66 ? 44 GLU J O 1 +ATOM 17475 C CB . GLU J 1 44 ? 58.049 33.404 31.788 1.00 83.80 ? 44 GLU J CB 1 +ATOM 17476 C CG . GLU J 1 44 ? 57.784 31.920 32.083 1.00 98.05 ? 44 GLU J CG 1 +ATOM 17477 C CD . GLU J 1 44 ? 59.063 31.043 32.152 1.00 127.73 ? 44 GLU J CD 1 +ATOM 17478 O OE1 . GLU J 1 44 ? 60.092 31.430 32.779 1.00 94.48 ? 44 GLU J OE1 1 +ATOM 17479 O OE2 . GLU J 1 44 ? 59.034 29.910 31.605 1.00 156.60 ? 44 GLU J OE2 1 +ATOM 17480 N N . THR J 1 45 ? 56.554 36.731 31.451 1.00 91.00 ? 45 THR J N 1 +ATOM 17481 C CA . THR J 1 45 ? 56.911 38.142 31.671 1.00 104.48 ? 45 THR J CA 1 +ATOM 17482 C C . THR J 1 45 ? 56.253 38.764 32.890 1.00 94.51 ? 45 THR J C 1 +ATOM 17483 O O . THR J 1 45 ? 56.892 39.476 33.651 1.00 129.09 ? 45 THR J O 1 +ATOM 17484 C CB . THR J 1 45 ? 56.628 39.018 30.440 1.00 102.65 ? 45 THR J CB 1 +ATOM 17485 O OG1 . THR J 1 45 ? 57.263 40.276 30.597 1.00 154.62 ? 45 THR J OG1 1 +ATOM 17486 C CG2 . THR J 1 45 ? 55.143 39.267 30.233 1.00 91.51 ? 45 THR J CG2 1 +ATOM 17487 N N . GLY J 1 46 ? 54.985 38.461 33.112 1.00 97.34 ? 46 GLY J N 1 +ATOM 17488 C CA . GLY J 1 46 ? 54.299 38.840 34.368 1.00 102.50 ? 46 GLY J CA 1 +ATOM 17489 C C . GLY J 1 46 ? 53.655 40.214 34.276 1.00 85.39 ? 46 GLY J C 1 +ATOM 17490 O O . GLY J 1 46 ? 53.289 40.847 35.286 1.00 83.34 ? 46 GLY J O 1 +ATOM 17491 N N . GLN J 1 47 ? 53.388 40.641 33.064 1.00 78.16 ? 47 GLN J N 1 +ATOM 17492 C CA . GLN J 1 47 ? 53.138 42.016 32.897 1.00 75.20 ? 47 GLN J CA 1 +ATOM 17493 C C . GLN J 1 47 ? 51.892 42.285 32.072 1.00 64.68 ? 47 GLN J C 1 +ATOM 17494 O O . GLN J 1 47 ? 51.616 41.581 31.093 1.00 69.33 ? 47 GLN J O 1 +ATOM 17495 C CB . GLN J 1 47 ? 54.362 42.606 32.308 1.00 64.50 ? 47 GLN J CB 1 +ATOM 17496 C CG . GLN J 1 47 ? 55.541 42.619 33.258 1.00 73.02 ? 47 GLN J CG 1 +ATOM 17497 C CD . GLN J 1 47 ? 55.201 43.206 34.616 1.00 97.06 ? 47 GLN J CD 1 +ATOM 17498 O OE1 . GLN J 1 47 ? 54.980 44.404 34.759 1.00 78.42 ? 47 GLN J OE1 1 +ATOM 17499 N NE2 . GLN J 1 47 ? 55.157 42.365 35.624 1.00 153.87 ? 47 GLN J NE2 1 +ATOM 17500 N N . PHE J 1 48 ? 51.120 43.255 32.540 1.00 50.31 ? 48 PHE J N 1 +ATOM 17501 C CA . PHE J 1 48 ? 49.925 43.693 31.873 1.00 70.64 ? 48 PHE J CA 1 +ATOM 17502 C C . PHE J 1 48 ? 49.978 45.170 31.550 1.00 90.27 ? 48 PHE J C 1 +ATOM 17503 O O . PHE J 1 48 ? 50.813 45.907 32.075 1.00 146.80 ? 48 PHE J O 1 +ATOM 17504 C CB . PHE J 1 48 ? 48.696 43.432 32.750 1.00 78.46 ? 48 PHE J CB 1 +ATOM 17505 C CG . PHE J 1 48 ? 48.423 41.988 32.955 1.00 61.92 ? 48 PHE J CG 1 +ATOM 17506 C CD1 . PHE J 1 48 ? 49.251 41.258 33.717 1.00 46.48 ? 48 PHE J CD1 1 +ATOM 17507 C CD2 . PHE J 1 48 ? 47.385 41.370 32.269 1.00 64.80 ? 48 PHE J CD2 1 +ATOM 17508 C CE1 . PHE J 1 48 ? 49.083 39.922 33.829 1.00 57.32 ? 48 PHE J CE1 1 +ATOM 17509 C CE2 . PHE J 1 48 ? 47.180 40.051 32.417 1.00 63.33 ? 48 PHE J CE2 1 +ATOM 17510 C CZ . PHE J 1 48 ? 48.045 39.318 33.187 1.00 73.40 ? 48 PHE J CZ 1 +ATOM 17511 N N . LYS J 1 49 ? 49.052 45.603 30.700 1.00 96.42 ? 49 LYS J N 1 +ATOM 17512 C CA . LYS J 1 49 ? 49.027 46.975 30.253 1.00 108.20 ? 49 LYS J CA 1 +ATOM 17513 C C . LYS J 1 49 ? 48.438 47.835 31.360 1.00 88.62 ? 49 LYS J C 1 +ATOM 17514 O O . LYS J 1 49 ? 47.510 47.408 32.056 1.00 69.61 ? 49 LYS J O 1 +ATOM 17515 C CB . LYS J 1 49 ? 48.249 47.109 28.916 1.00 126.59 ? 49 LYS J CB 1 +ATOM 17516 C CG . LYS J 1 49 ? 48.957 46.395 27.765 1.00 112.50 ? 49 LYS J CG 1 +ATOM 17517 C CD . LYS J 1 49 ? 48.404 46.638 26.374 1.00 102.74 ? 49 LYS J CD 1 +ATOM 17518 C CE . LYS J 1 49 ? 49.375 45.978 25.396 1.00 120.32 ? 49 LYS J CE 1 +ATOM 17519 N NZ . LYS J 1 49 ? 49.050 46.135 23.947 1.00 160.35 ? 49 LYS J NZ 1 +ATOM 17520 N N . PRO J 1 50 ? 48.969 49.058 31.502 1.00 70.87 ? 50 PRO J N 1 +ATOM 17521 C CA . PRO J 1 50 ? 48.392 50.059 32.382 1.00 77.10 ? 50 PRO J CA 1 +ATOM 17522 C C . PRO J 1 50 ? 47.078 50.700 31.903 1.00 91.78 ? 50 PRO J C 1 +ATOM 17523 O O . PRO J 1 50 ? 46.685 50.573 30.734 1.00 98.76 ? 50 PRO J O 1 +ATOM 17524 C CB . PRO J 1 50 ? 49.500 51.114 32.461 1.00 75.29 ? 50 PRO J CB 1 +ATOM 17525 C CG . PRO J 1 50 ? 50.182 51.033 31.151 1.00 65.40 ? 50 PRO J CG 1 +ATOM 17526 C CD . PRO J 1 50 ? 50.086 49.598 30.706 1.00 58.20 ? 50 PRO J CD 1 +ATOM 17527 N N . TYR J 1 51 ? 46.414 51.425 32.799 1.00 101.93 ? 51 TYR J N 1 +ATOM 17528 C CA . TYR J 1 51 ? 45.273 52.252 32.392 1.00 105.43 ? 51 TYR J CA 1 +ATOM 17529 C C . TYR J 1 51 ? 45.653 53.090 31.169 1.00 100.28 ? 51 TYR J C 1 +ATOM 17530 O O . TYR J 1 51 ? 46.750 53.683 31.163 1.00 148.42 ? 51 TYR J O 1 +ATOM 17531 C CB . TYR J 1 51 ? 44.831 53.172 33.536 1.00 89.43 ? 51 TYR J CB 1 +ATOM 17532 C CG . TYR J 1 51 ? 43.481 53.769 33.267 1.00 75.12 ? 51 TYR J CG 1 +ATOM 17533 C CD1 . TYR J 1 51 ? 42.344 53.092 33.625 1.00 80.57 ? 51 TYR J CD1 1 +ATOM 17534 C CD2 . TYR J 1 51 ? 43.340 55.008 32.652 1.00 97.45 ? 51 TYR J CD2 1 +ATOM 17535 C CE1 . TYR J 1 51 ? 41.088 53.607 33.362 1.00 103.12 ? 51 TYR J CE1 1 +ATOM 17536 C CE2 . TYR J 1 51 ? 42.077 55.557 32.411 1.00 108.54 ? 51 TYR J CE2 1 +ATOM 17537 C CZ . TYR J 1 51 ? 40.956 54.824 32.744 1.00 105.89 ? 51 TYR J CZ 1 +ATOM 17538 O OH . TYR J 1 51 ? 39.679 55.297 32.543 1.00 119.19 ? 51 TYR J OH 1 +ATOM 17539 N N . PRO J 1 52 ? 44.776 53.158 30.141 1.00 73.04 ? 52 PRO J N 1 +ATOM 17540 C CA . PRO J 1 52 ? 43.384 52.742 30.102 1.00 92.02 ? 52 PRO J CA 1 +ATOM 17541 C C . PRO J 1 52 ? 43.135 51.388 29.493 1.00 130.91 ? 52 PRO J C 1 +ATOM 17542 O O . PRO J 1 52 ? 41.980 51.087 29.150 1.00 156.62 ? 52 PRO J O 1 +ATOM 17543 C CB . PRO J 1 52 ? 42.738 53.784 29.198 1.00 97.43 ? 52 PRO J CB 1 +ATOM 17544 C CG . PRO J 1 52 ? 43.818 54.113 28.225 1.00 99.53 ? 52 PRO J CG 1 +ATOM 17545 C CD . PRO J 1 52 ? 45.107 54.023 28.998 1.00 83.79 ? 52 PRO J CD 1 +ATOM 17546 N N . ALA J 1 53 ? 44.161 50.542 29.418 1.00 143.87 ? 53 ALA J N 1 +ATOM 17547 C CA . ALA J 1 53 ? 43.946 49.190 28.914 1.00 150.94 ? 53 ALA J CA 1 +ATOM 17548 C C . ALA J 1 53 ? 42.995 48.394 29.822 1.00 115.24 ? 53 ALA J C 1 +ATOM 17549 O O . ALA J 1 53 ? 42.830 48.724 31.018 1.00 85.82 ? 53 ALA J O 1 +ATOM 17550 C CB . ALA J 1 53 ? 45.274 48.466 28.756 1.00 145.42 ? 53 ALA J CB 1 +ATOM 17551 N N . SER J 1 54 ? 42.382 47.353 29.260 1.00 83.02 ? 54 SER J N 1 +ATOM 17552 C CA . SER J 1 54 ? 41.729 46.378 30.108 1.00 74.86 ? 54 SER J CA 1 +ATOM 17553 C C . SER J 1 54 ? 42.725 45.763 31.084 1.00 76.32 ? 54 SER J C 1 +ATOM 17554 O O . SER J 1 54 ? 43.926 45.577 30.808 1.00 58.61 ? 54 SER J O 1 +ATOM 17555 C CB . SER J 1 54 ? 41.098 45.258 29.323 1.00 77.78 ? 54 SER J CB 1 +ATOM 17556 O OG . SER J 1 54 ? 40.882 44.100 30.134 1.00 71.16 ? 54 SER J OG 1 +ATOM 17557 N N . ASN J 1 55 ? 42.232 45.545 32.296 1.00 72.14 ? 55 ASN J N 1 +ATOM 17558 C CA . ASN J 1 55 ? 43.047 44.991 33.364 1.00 64.01 ? 55 ASN J CA 1 +ATOM 17559 C C . ASN J 1 55 ? 43.751 43.750 32.886 1.00 61.67 ? 55 ASN J C 1 +ATOM 17560 O O . ASN J 1 55 ? 44.852 43.378 33.374 1.00 65.72 ? 55 ASN J O 1 +ATOM 17561 C CB . ASN J 1 55 ? 42.143 44.670 34.536 1.00 70.58 ? 55 ASN J CB 1 +ATOM 17562 C CG . ASN J 1 55 ? 42.910 44.372 35.789 1.00 109.26 ? 55 ASN J CG 1 +ATOM 17563 O OD1 . ASN J 1 55 ? 44.056 44.783 35.970 1.00 187.36 ? 55 ASN J OD1 1 +ATOM 17564 N ND2 . ASN J 1 55 ? 42.241 43.737 36.704 1.00 128.68 ? 55 ASN J ND2 1 +ATOM 17565 N N . PHE J 1 56 ? 43.096 43.092 31.931 1.00 79.38 ? 56 PHE J N 1 +ATOM 17566 C CA . PHE J 1 56 ? 43.469 41.734 31.513 1.00 100.80 ? 56 PHE J CA 1 +ATOM 17567 C C . PHE J 1 56 ? 44.333 41.756 30.287 1.00 98.62 ? 56 PHE J C 1 +ATOM 17568 O O . PHE J 1 56 ? 44.696 40.689 29.780 1.00 111.81 ? 56 PHE J O 1 +ATOM 17569 C CB . PHE J 1 56 ? 42.237 40.863 31.166 1.00 76.62 ? 56 PHE J CB 1 +ATOM 17570 C CG . PHE J 1 56 ? 41.291 40.678 32.293 1.00 58.54 ? 56 PHE J CG 1 +ATOM 17571 C CD1 . PHE J 1 56 ? 41.705 40.114 33.489 1.00 47.01 ? 56 PHE J CD1 1 +ATOM 17572 C CD2 . PHE J 1 56 ? 40.036 41.193 32.203 1.00 64.40 ? 56 PHE J CD2 1 +ATOM 17573 C CE1 . PHE J 1 56 ? 40.872 40.083 34.572 1.00 50.21 ? 56 PHE J CE1 1 +ATOM 17574 C CE2 . PHE J 1 56 ? 39.167 41.112 33.269 1.00 77.24 ? 56 PHE J CE2 1 +ATOM 17575 C CZ . PHE J 1 56 ? 39.592 40.563 34.464 1.00 69.04 ? 56 PHE J CZ 1 +ATOM 17576 N N . SER J 1 57 ? 44.600 42.934 29.747 1.00 76.76 ? 57 SER J N 1 +ATOM 17577 C CA . SER J 1 57 ? 45.410 42.975 28.555 1.00 87.85 ? 57 SER J CA 1 +ATOM 17578 C C . SER J 1 57 ? 46.874 42.716 28.943 1.00 59.62 ? 57 SER J C 1 +ATOM 17579 O O . SER J 1 57 ? 47.508 43.521 29.632 1.00 73.67 ? 57 SER J O 1 +ATOM 17580 C CB . SER J 1 57 ? 45.213 44.302 27.810 1.00 120.31 ? 57 SER J CB 1 +ATOM 17581 O OG . SER J 1 57 ? 43.947 44.320 27.138 1.00 94.17 ? 57 SER J OG 1 +ATOM 17582 N N . THR J 1 58 ? 47.406 41.598 28.482 1.00 44.53 ? 58 THR J N 1 +ATOM 17583 C CA . THR J 1 58 ? 48.796 41.318 28.678 1.00 63.28 ? 58 THR J CA 1 +ATOM 17584 C C . THR J 1 58 ? 49.718 42.269 27.925 1.00 73.10 ? 58 THR J C 1 +ATOM 17585 O O . THR J 1 58 ? 49.419 42.765 26.866 1.00 62.93 ? 58 THR J O 1 +ATOM 17586 C CB . THR J 1 58 ? 49.118 39.919 28.202 1.00 69.00 ? 58 THR J CB 1 +ATOM 17587 O OG1 . THR J 1 58 ? 48.881 39.831 26.804 1.00 65.18 ? 58 THR J OG1 1 +ATOM 17588 C CG2 . THR J 1 58 ? 48.218 38.948 28.891 1.00 76.22 ? 58 THR J CG2 1 +ATOM 17589 N N . ALA J 1 59 ? 50.898 42.457 28.451 1.00 92.57 ? 59 ALA J N 1 +ATOM 17590 C CA . ALA J 1 59 ? 51.779 43.379 27.797 1.00 89.11 ? 59 ALA J CA 1 +ATOM 17591 C C . ALA J 1 59 ? 52.387 42.752 26.567 1.00 61.29 ? 59 ALA J C 1 +ATOM 17592 O O . ALA J 1 59 ? 52.882 43.469 25.694 1.00 83.20 ? 59 ALA J O 1 +ATOM 17593 C CB . ALA J 1 59 ? 52.860 43.842 28.740 1.00 112.35 ? 59 ALA J CB 1 +ATOM 17594 N N . VAL J 1 60 ? 52.316 41.440 26.472 1.00 45.17 ? 60 VAL J N 1 +ATOM 17595 C CA . VAL J 1 60 ? 52.997 40.739 25.427 1.00 61.82 ? 60 VAL J CA 1 +ATOM 17596 C C . VAL J 1 60 ? 52.022 39.727 24.868 1.00 78.50 ? 60 VAL J C 1 +ATOM 17597 O O . VAL J 1 60 ? 51.344 39.043 25.619 1.00 116.43 ? 60 VAL J O 1 +ATOM 17598 C CB . VAL J 1 60 ? 54.254 40.021 25.982 1.00 68.23 ? 60 VAL J CB 1 +ATOM 17599 C CG1 . VAL J 1 60 ? 54.987 39.204 24.905 1.00 56.27 ? 60 VAL J CG1 1 +ATOM 17600 C CG2 . VAL J 1 60 ? 55.210 41.044 26.617 1.00 77.11 ? 60 VAL J CG2 1 +ATOM 17601 N N . PRO J 1 61 ? 52.038 39.522 23.548 1.00 83.63 ? 61 PRO J N 1 +ATOM 17602 C CA . PRO J 1 61 ? 51.149 38.513 22.980 1.00 99.10 ? 61 PRO J CA 1 +ATOM 17603 C C . PRO J 1 61 ? 51.506 37.088 23.388 1.00 107.15 ? 61 PRO J C 1 +ATOM 17604 O O . PRO J 1 61 ? 52.700 36.759 23.566 1.00 102.45 ? 61 PRO J O 1 +ATOM 17605 C CB . PRO J 1 61 ? 51.334 38.683 21.473 1.00 105.83 ? 61 PRO J CB 1 +ATOM 17606 C CG . PRO J 1 61 ? 52.661 39.336 21.322 1.00 92.79 ? 61 PRO J CG 1 +ATOM 17607 C CD . PRO J 1 61 ? 52.791 40.232 22.510 1.00 87.73 ? 61 PRO J CD 1 +ATOM 17608 N N . GLN J 1 62 ? 50.472 36.263 23.543 1.00 81.89 ? 62 GLN J N 1 +ATOM 17609 C CA . GLN J 1 62 ? 50.647 34.919 24.087 1.00 108.68 ? 62 GLN J CA 1 +ATOM 17610 C C . GLN J 1 62 ? 50.938 33.938 22.987 1.00 85.42 ? 62 GLN J C 1 +ATOM 17611 O O . GLN J 1 62 ? 50.479 32.806 23.036 1.00 117.14 ? 62 GLN J O 1 +ATOM 17612 C CB . GLN J 1 62 ? 49.376 34.469 24.846 1.00 132.47 ? 62 GLN J CB 1 +ATOM 17613 C CG . GLN J 1 62 ? 48.873 35.455 25.895 1.00 127.01 ? 62 GLN J CG 1 +ATOM 17614 C CD . GLN J 1 62 ? 49.908 35.753 26.966 1.00 102.18 ? 62 GLN J CD 1 +ATOM 17615 O OE1 . GLN J 1 62 ? 50.147 34.945 27.853 1.00 103.41 ? 62 GLN J OE1 1 +ATOM 17616 N NE2 . GLN J 1 62 ? 50.578 36.877 26.832 1.00 93.43 ? 62 GLN J NE2 1 +ATOM 17617 N N . SER J 1 63 ? 51.688 34.370 21.999 1.00 68.38 ? 63 SER J N 1 +ATOM 17618 C CA . SER J 1 63 ? 51.682 33.698 20.722 1.00 93.98 ? 63 SER J CA 1 +ATOM 17619 C C . SER J 1 63 ? 53.078 33.252 20.329 1.00 97.04 ? 63 SER J C 1 +ATOM 17620 O O . SER J 1 63 ? 53.315 32.829 19.190 1.00 110.85 ? 63 SER J O 1 +ATOM 17621 C CB . SER J 1 63 ? 51.064 34.623 19.639 1.00 139.58 ? 63 SER J CB 1 +ATOM 17622 O OG . SER J 1 63 ? 51.776 35.836 19.436 1.00 118.75 ? 63 SER J OG 1 +ATOM 17623 N N . ALA J 1 64 ? 54.004 33.395 21.267 1.00 85.35 ? 64 ALA J N 1 +ATOM 17624 C CA . ALA J 1 64 ? 55.415 33.167 21.004 1.00 100.06 ? 64 ALA J CA 1 +ATOM 17625 C C . ALA J 1 64 ? 55.712 31.780 20.404 1.00 111.66 ? 64 ALA J C 1 +ATOM 17626 O O . ALA J 1 64 ? 56.552 31.627 19.498 1.00 95.99 ? 64 ALA J O 1 +ATOM 17627 C CB . ALA J 1 64 ? 56.187 33.350 22.288 1.00 95.91 ? 64 ALA J CB 1 +ATOM 17628 N N . THR J 1 65 ? 54.978 30.785 20.882 1.00 119.51 ? 65 THR J N 1 +ATOM 17629 C CA . THR J 1 65 ? 55.133 29.414 20.432 1.00 119.62 ? 65 THR J CA 1 +ATOM 17630 C C . THR J 1 65 ? 55.036 29.308 18.919 1.00 128.35 ? 65 THR J C 1 +ATOM 17631 O O . THR J 1 65 ? 55.876 28.676 18.274 1.00 97.02 ? 65 THR J O 1 +ATOM 17632 C CB . THR J 1 65 ? 54.019 28.548 21.034 1.00 127.86 ? 65 THR J CB 1 +ATOM 17633 O OG1 . THR J 1 65 ? 53.791 28.964 22.383 1.00 147.24 ? 65 THR J OG1 1 +ATOM 17634 C CG2 . THR J 1 65 ? 54.397 27.061 20.991 1.00 128.35 ? 65 THR J CG2 1 +ATOM 17635 N N . ALA J 1 66 ? 53.969 29.879 18.362 1.00 126.14 ? 66 ALA J N 1 +ATOM 17636 C CA . ALA J 1 66 ? 53.712 29.753 16.944 1.00 108.76 ? 66 ALA J CA 1 +ATOM 17637 C C . ALA J 1 66 ? 54.752 30.551 16.138 1.00 146.31 ? 66 ALA J C 1 +ATOM 17638 O O . ALA J 1 66 ? 55.159 30.131 15.044 1.00 186.09 ? 66 ALA J O 1 +ATOM 17639 C CB . ALA J 1 66 ? 52.311 30.213 16.642 1.00 94.53 ? 66 ALA J CB 1 +ATOM 17640 N N . MET J 1 67 ? 55.204 31.679 16.700 1.00 156.65 ? 67 MET J N 1 +ATOM 17641 C CA . MET J 1 67 ? 56.245 32.512 16.066 1.00 129.36 ? 67 MET J CA 1 +ATOM 17642 C C . MET J 1 67 ? 57.564 31.760 15.992 1.00 105.21 ? 67 MET J C 1 +ATOM 17643 O O . MET J 1 67 ? 58.230 31.750 14.939 1.00 93.67 ? 67 MET J O 1 +ATOM 17644 C CB . MET J 1 67 ? 56.478 33.806 16.842 1.00 112.04 ? 67 MET J CB 1 +ATOM 17645 C CG . MET J 1 67 ? 55.345 34.819 16.775 1.00 108.60 ? 67 MET J CG 1 +ATOM 17646 S SD . MET J 1 67 ? 55.585 36.130 17.986 1.00 110.68 ? 67 MET J SD 1 +ATOM 17647 C CE . MET J 1 67 ? 54.241 37.249 17.551 1.00 101.22 ? 67 MET J CE 1 +ATOM 17648 N N . LEU J 1 68 ? 57.883 31.043 17.070 1.00 94.90 ? 68 LEU J N 1 +ATOM 17649 C CA . LEU J 1 68 ? 59.082 30.219 17.066 1.00 131.73 ? 68 LEU J CA 1 +ATOM 17650 C C . LEU J 1 68 ? 59.008 29.095 16.028 1.00 146.84 ? 68 LEU J C 1 +ATOM 17651 O O . LEU J 1 68 ? 59.976 28.850 15.314 1.00 116.34 ? 68 LEU J O 1 +ATOM 17652 C CB . LEU J 1 68 ? 59.349 29.599 18.436 1.00 137.09 ? 68 LEU J CB 1 +ATOM 17653 C CG . LEU J 1 68 ? 60.504 28.561 18.432 1.00 116.04 ? 68 LEU J CG 1 +ATOM 17654 C CD1 . LEU J 1 68 ? 61.830 29.238 18.122 1.00 106.63 ? 68 LEU J CD1 1 +ATOM 17655 C CD2 . LEU J 1 68 ? 60.593 27.787 19.739 1.00 86.68 ? 68 LEU J CD2 1 +ATOM 17656 N N . VAL J 1 69 ? 57.882 28.382 15.980 1.00 132.99 ? 69 VAL J N 1 +ATOM 17657 C CA . VAL J 1 69 ? 57.727 27.282 15.022 1.00 106.98 ? 69 VAL J CA 1 +ATOM 17658 C C . VAL J 1 69 ? 57.899 27.841 13.614 1.00 137.27 ? 69 VAL J C 1 +ATOM 17659 O O . VAL J 1 69 ? 58.547 27.238 12.764 1.00 161.28 ? 69 VAL J O 1 +ATOM 17660 C CB . VAL J 1 69 ? 56.351 26.591 15.136 1.00 115.55 ? 69 VAL J CB 1 +ATOM 17661 C CG1 . VAL J 1 69 ? 56.169 25.596 14.006 1.00 109.34 ? 69 VAL J CG1 1 +ATOM 17662 C CG2 . VAL J 1 69 ? 56.192 25.875 16.468 1.00 126.39 ? 69 VAL J CG2 1 +ATOM 17663 N N . THR J 1 70 ? 57.279 28.994 13.361 1.00 155.18 ? 70 THR J N 1 +ATOM 17664 C CA . THR J 1 70 ? 57.336 29.632 12.043 1.00 116.95 ? 70 THR J CA 1 +ATOM 17665 C C . THR J 1 70 ? 58.761 30.023 11.701 1.00 85.93 ? 70 THR J C 1 +ATOM 17666 O O . THR J 1 70 ? 59.232 29.776 10.578 1.00 73.63 ? 70 THR J O 1 +ATOM 17667 C CB . THR J 1 70 ? 56.414 30.860 11.985 1.00 107.84 ? 70 THR J CB 1 +ATOM 17668 O OG1 . THR J 1 70 ? 55.081 30.447 12.335 1.00 126.75 ? 70 THR J OG1 1 +ATOM 17669 C CG2 . THR J 1 70 ? 56.414 31.478 10.583 1.00 111.74 ? 70 THR J CG2 1 +ATOM 17670 N N . ALA J 1 71 ? 59.447 30.627 12.663 1.00 83.26 ? 71 ALA J N 1 +ATOM 17671 C CA . ALA J 1 71 ? 60.844 30.993 12.457 1.00 105.81 ? 71 ALA J CA 1 +ATOM 17672 C C . ALA J 1 71 ? 61.711 29.754 12.190 1.00 97.39 ? 71 ALA J C 1 +ATOM 17673 O O . ALA J 1 71 ? 62.589 29.767 11.292 1.00 91.74 ? 71 ALA J O 1 +ATOM 17674 C CB . ALA J 1 71 ? 61.379 31.760 13.654 1.00 111.78 ? 71 ALA J CB 1 +ATOM 17675 N N . LEU J 1 72 ? 61.457 28.686 12.944 1.00 78.67 ? 72 LEU J N 1 +ATOM 17676 C CA . LEU J 1 72 ? 62.185 27.418 12.737 1.00 105.57 ? 72 LEU J CA 1 +ATOM 17677 C C . LEU J 1 72 ? 61.952 26.850 11.336 1.00 127.57 ? 72 LEU J C 1 +ATOM 17678 O O . LEU J 1 72 ? 62.801 26.141 10.795 1.00 98.63 ? 72 LEU J O 1 +ATOM 17679 C CB . LEU J 1 72 ? 61.778 26.365 13.767 1.00 82.76 ? 72 LEU J CB 1 +ATOM 17680 C CG . LEU J 1 72 ? 62.203 26.672 15.184 1.00 82.96 ? 72 LEU J CG 1 +ATOM 17681 C CD1 . LEU J 1 72 ? 61.410 25.821 16.133 1.00 78.66 ? 72 LEU J CD1 1 +ATOM 17682 C CD2 . LEU J 1 72 ? 63.688 26.438 15.393 1.00 102.18 ? 72 LEU J CD2 1 +ATOM 17683 N N . LYS J 1 73 ? 60.810 27.187 10.737 1.00 132.04 ? 73 LYS J N 1 +ATOM 17684 C CA . LYS J 1 73 ? 60.505 26.710 9.388 1.00 117.27 ? 73 LYS J CA 1 +ATOM 17685 C C . LYS J 1 73 ? 61.135 27.594 8.332 1.00 101.26 ? 73 LYS J C 1 +ATOM 17686 O O . LYS J 1 73 ? 61.715 27.088 7.375 1.00 102.53 ? 73 LYS J O 1 +ATOM 17687 C CB . LYS J 1 73 ? 58.995 26.627 9.147 1.00 132.56 ? 73 LYS J CB 1 +ATOM 17688 C CG . LYS J 1 73 ? 58.614 25.850 7.881 1.00 134.23 ? 73 LYS J CG 1 +ATOM 17689 C CD . LYS J 1 73 ? 57.097 25.795 7.675 1.00 134.71 ? 73 LYS J CD 1 +ATOM 17690 C CE . LYS J 1 73 ? 56.724 25.681 6.202 1.00 138.53 ? 73 LYS J CE 1 +ATOM 17691 N NZ . LYS J 1 73 ? 56.087 24.384 5.852 1.00 131.01 ? 73 LYS J NZ 1 +ATOM 17692 N N . ASP J 1 74 ? 60.986 28.908 8.487 1.00 90.51 ? 74 ASP J N 1 +ATOM 17693 C CA . ASP J 1 74 ? 61.482 29.861 7.489 1.00 95.17 ? 74 ASP J CA 1 +ATOM 17694 C C . ASP J 1 74 ? 62.990 29.711 7.289 1.00 94.37 ? 74 ASP J C 1 +ATOM 17695 O O . ASP J 1 74 ? 63.507 30.015 6.209 1.00 107.14 ? 74 ASP J O 1 +ATOM 17696 C CB . ASP J 1 74 ? 61.137 31.309 7.880 1.00 87.17 ? 74 ASP J CB 1 +ATOM 17697 C CG . ASP J 1 74 ? 59.646 31.630 7.759 1.00 97.44 ? 74 ASP J CG 1 +ATOM 17698 O OD1 . ASP J 1 74 ? 58.908 30.962 6.983 1.00 67.42 ? 74 ASP J OD1 1 +ATOM 17699 O OD2 . ASP J 1 74 ? 59.184 32.475 8.576 1.00 115.72 ? 74 ASP J OD2 1 +ATOM 17700 N N . SER J 1 75 ? 63.690 29.288 8.343 1.00 93.36 ? 75 SER J N 1 +ATOM 17701 C CA . SER J 1 75 ? 65.152 29.179 8.317 1.00 120.15 ? 75 SER J CA 1 +ATOM 17702 C C . SER J 1 75 ? 65.643 28.152 7.297 1.00 118.71 ? 75 SER J C 1 +ATOM 17703 O O . SER J 1 75 ? 66.793 28.217 6.840 1.00 120.22 ? 75 SER J O 1 +ATOM 17704 C CB . SER J 1 75 ? 65.697 28.813 9.706 1.00 129.32 ? 75 SER J CB 1 +ATOM 17705 O OG . SER J 1 75 ? 65.680 27.407 9.911 1.00 120.07 ? 75 SER J OG 1 +ATOM 17706 N N . ARG J 1 76 ? 64.780 27.194 6.983 1.00 116.97 ? 76 ARG J N 1 +ATOM 17707 C CA . ARG J 1 76 ? 65.114 26.082 6.099 1.00 148.75 ? 76 ARG J CA 1 +ATOM 17708 C C . ARG J 1 76 ? 66.267 25.261 6.662 1.00 133.52 ? 76 ARG J C 1 +ATOM 17709 O O . ARG J 1 76 ? 67.069 24.701 5.922 1.00 134.65 ? 76 ARG J O 1 +ATOM 17710 C CB . ARG J 1 76 ? 65.450 26.571 4.695 1.00 166.47 ? 76 ARG J CB 1 +ATOM 17711 C CG . ARG J 1 76 ? 64.328 27.334 3.993 1.00 150.59 ? 76 ARG J CG 1 +ATOM 17712 C CD . ARG J 1 76 ? 64.763 27.743 2.594 1.00 135.38 ? 76 ARG J CD 1 +ATOM 17713 N NE . ARG J 1 76 ? 65.805 28.772 2.632 1.00 164.03 ? 76 ARG J NE 1 +ATOM 17714 C CZ . ARG J 1 76 ? 67.124 28.547 2.603 1.00 162.18 ? 76 ARG J CZ 1 +ATOM 17715 N NH1 . ARG J 1 76 ? 67.619 27.311 2.525 1.00 156.45 ? 76 ARG J NH1 1 +ATOM 17716 N NH2 . ARG J 1 76 ? 67.959 29.577 2.668 1.00 134.78 ? 76 ARG J NH2 1 +ATOM 17717 N N . TRP J 1 77 ? 66.258 25.113 7.980 1.00 131.79 ? 77 TRP J N 1 +ATOM 17718 C CA . TRP J 1 77 ? 67.107 24.155 8.676 1.00 133.50 ? 77 TRP J CA 1 +ATOM 17719 C C . TRP J 1 77 ? 66.291 23.038 9.369 1.00 147.53 ? 77 TRP J C 1 +ATOM 17720 O O . TRP J 1 77 ? 66.746 21.900 9.484 1.00 92.34 ? 77 TRP J O 1 +ATOM 17721 C CB . TRP J 1 77 ? 67.921 24.910 9.711 1.00 139.03 ? 77 TRP J CB 1 +ATOM 17722 C CG . TRP J 1 77 ? 69.226 25.380 9.208 1.00 124.11 ? 77 TRP J CG 1 +ATOM 17723 C CD1 . TRP J 1 77 ? 69.455 26.471 8.424 1.00 116.51 ? 77 TRP J CD1 1 +ATOM 17724 C CD2 . TRP J 1 77 ? 70.507 24.840 9.539 1.00 111.73 ? 77 TRP J CD2 1 +ATOM 17725 N NE1 . TRP J 1 77 ? 70.800 26.644 8.251 1.00 130.07 ? 77 TRP J NE1 1 +ATOM 17726 C CE2 . TRP J 1 77 ? 71.467 25.643 8.914 1.00 118.05 ? 77 TRP J CE2 1 +ATOM 17727 C CE3 . TRP J 1 77 ? 70.936 23.753 10.309 1.00 108.46 ? 77 TRP J CE3 1 +ATOM 17728 C CZ2 . TRP J 1 77 ? 72.828 25.372 8.998 1.00 119.59 ? 77 TRP J CZ2 1 +ATOM 17729 C CZ3 . TRP J 1 77 ? 72.290 23.496 10.400 1.00 101.75 ? 77 TRP J CZ3 1 +ATOM 17730 C CH2 . TRP J 1 77 ? 73.216 24.294 9.744 1.00 100.63 ? 77 TRP J CH2 1 +ATOM 17731 N N . PHE J 1 78 ? 65.085 23.392 9.824 1.00 156.36 ? 78 PHE J N 1 +ATOM 17732 C CA . PHE J 1 78 ? 64.236 22.510 10.629 1.00 107.30 ? 78 PHE J CA 1 +ATOM 17733 C C . PHE J 1 78 ? 62.870 22.240 9.996 1.00 92.70 ? 78 PHE J C 1 +ATOM 17734 O O . PHE J 1 78 ? 62.266 23.129 9.390 1.00 63.41 ? 78 PHE J O 1 +ATOM 17735 C CB . PHE J 1 78 ? 63.973 23.164 11.961 1.00 98.59 ? 78 PHE J CB 1 +ATOM 17736 C CG . PHE J 1 78 ? 65.208 23.545 12.684 1.00 84.44 ? 78 PHE J CG 1 +ATOM 17737 C CD1 . PHE J 1 78 ? 66.013 22.564 13.282 1.00 70.48 ? 78 PHE J CD1 1 +ATOM 17738 C CD2 . PHE J 1 78 ? 65.559 24.891 12.789 1.00 66.96 ? 78 PHE J CD2 1 +ATOM 17739 C CE1 . PHE J 1 78 ? 67.123 22.931 14.008 1.00 94.01 ? 78 PHE J CE1 1 +ATOM 17740 C CE2 . PHE J 1 78 ? 66.681 25.261 13.497 1.00 84.17 ? 78 PHE J CE2 1 +ATOM 17741 C CZ . PHE J 1 78 ? 67.474 24.280 14.102 1.00 106.00 ? 78 PHE J CZ 1 +ATOM 17742 N N . ILE J 1 79 ? 62.395 21.008 10.160 1.00 95.77 ? 79 ILE J N 1 +ATOM 17743 C CA . ILE J 1 79 ? 60.992 20.643 9.935 1.00 96.87 ? 79 ILE J CA 1 +ATOM 17744 C C . ILE J 1 79 ? 60.311 20.632 11.297 1.00 104.59 ? 79 ILE J C 1 +ATOM 17745 O O . ILE J 1 79 ? 60.814 19.982 12.225 1.00 77.75 ? 79 ILE J O 1 +ATOM 17746 C CB . ILE J 1 79 ? 60.864 19.224 9.362 1.00 102.62 ? 79 ILE J CB 1 +ATOM 17747 C CG1 . ILE J 1 79 ? 61.813 19.034 8.178 1.00 133.43 ? 79 ILE J CG1 1 +ATOM 17748 C CG2 . ILE J 1 79 ? 59.427 18.936 8.945 1.00 81.58 ? 79 ILE J CG2 1 +ATOM 17749 C CD1 . ILE J 1 79 ? 62.182 17.585 7.903 1.00 127.39 ? 79 ILE J CD1 1 +ATOM 17750 N N . PRO J 1 80 ? 59.248 21.440 11.448 1.00 98.97 ? 80 PRO J N 1 +ATOM 17751 C CA . PRO J 1 80 ? 58.622 21.425 12.733 1.00 78.43 ? 80 PRO J CA 1 +ATOM 17752 C C . PRO J 1 80 ? 57.553 20.380 12.744 1.00 67.73 ? 80 PRO J C 1 +ATOM 17753 O O . PRO J 1 80 ? 56.777 20.297 11.817 1.00 44.34 ? 80 PRO J O 1 +ATOM 17754 C CB . PRO J 1 80 ? 58.033 22.837 12.865 1.00 68.68 ? 80 PRO J CB 1 +ATOM 17755 C CG . PRO J 1 80 ? 58.871 23.659 11.979 1.00 97.56 ? 80 PRO J CG 1 +ATOM 17756 C CD . PRO J 1 80 ? 59.084 22.751 10.800 1.00 110.89 ? 80 PRO J CD 1 +ATOM 17757 N N . LEU J 1 81 ? 57.563 19.558 13.790 1.00 74.09 ? 81 LEU J N 1 +ATOM 17758 C CA . LEU J 1 81 ? 56.491 18.624 14.054 1.00 66.66 ? 81 LEU J CA 1 +ATOM 17759 C C . LEU J 1 81 ? 55.462 19.216 15.003 1.00 84.07 ? 81 LEU J C 1 +ATOM 17760 O O . LEU J 1 81 ? 55.805 20.047 15.882 1.00 79.34 ? 81 LEU J O 1 +ATOM 17761 C CB . LEU J 1 81 ? 57.050 17.381 14.648 1.00 66.08 ? 81 LEU J CB 1 +ATOM 17762 C CG . LEU J 1 81 ? 58.173 16.817 13.784 1.00 92.64 ? 81 LEU J CG 1 +ATOM 17763 C CD1 . LEU J 1 81 ? 58.770 15.631 14.494 1.00 89.17 ? 81 LEU J CD1 1 +ATOM 17764 C CD2 . LEU J 1 81 ? 57.643 16.405 12.429 1.00 129.12 ? 81 LEU J CD2 1 +ATOM 17765 N N . GLU J 1 82 ? 54.192 18.966 14.666 1.00 104.58 ? 82 GLU J N 1 +ATOM 17766 C CA . GLU J 1 82 ? 53.058 19.650 15.314 1.00 109.40 ? 82 GLU J CA 1 +ATOM 17767 C C . GLU J 1 82 ? 52.741 18.999 16.635 1.00 113.83 ? 82 GLU J C 1 +ATOM 17768 O O . GLU J 1 82 ? 52.302 17.847 16.687 1.00 75.87 ? 82 GLU J O 1 +ATOM 17769 C CB . GLU J 1 82 ? 51.801 19.678 14.437 1.00 100.81 ? 82 GLU J CB 1 +ATOM 17770 C CG . GLU J 1 82 ? 50.571 20.309 15.104 1.00 87.41 ? 82 GLU J CG 1 +ATOM 17771 C CD . GLU J 1 82 ? 50.650 21.840 15.305 1.00 79.58 ? 82 GLU J CD 1 +ATOM 17772 O OE1 . GLU J 1 82 ? 51.658 22.383 15.782 1.00 94.05 ? 82 GLU J OE1 1 +ATOM 17773 O OE2 . GLU J 1 82 ? 49.681 22.545 14.975 1.00 66.28 ? 82 GLU J OE2 1 +ATOM 17774 N N . ARG J 1 83 ? 53.059 19.739 17.697 1.00 128.65 ? 83 ARG J N 1 +ATOM 17775 C CA . ARG J 1 83 ? 52.769 19.319 19.057 1.00 94.43 ? 83 ARG J CA 1 +ATOM 17776 C C . ARG J 1 83 ? 51.894 20.335 19.796 1.00 73.74 ? 83 ARG J C 1 +ATOM 17777 O O . ARG J 1 83 ? 51.261 19.986 20.784 1.00 59.63 ? 83 ARG J O 1 +ATOM 17778 C CB . ARG J 1 83 ? 54.068 19.045 19.825 1.00 77.07 ? 83 ARG J CB 1 +ATOM 17779 C CG . ARG J 1 83 ? 54.982 18.029 19.171 1.00 51.63 ? 83 ARG J CG 1 +ATOM 17780 C CD . ARG J 1 83 ? 54.425 16.668 19.203 1.00 37.92 ? 83 ARG J CD 1 +ATOM 17781 N NE . ARG J 1 83 ? 55.513 15.802 18.776 1.00 47.89 ? 83 ARG J NE 1 +ATOM 17782 C CZ . ARG J 1 83 ? 55.582 15.191 17.601 1.00 78.25 ? 83 ARG J CZ 1 +ATOM 17783 N NH1 . ARG J 1 83 ? 54.634 15.365 16.665 1.00 90.91 ? 83 ARG J NH1 1 +ATOM 17784 N NH2 . ARG J 1 83 ? 56.620 14.384 17.337 1.00 88.14 ? 83 ARG J NH2 1 +ATOM 17785 N N . GLN J 1 84 ? 51.832 21.582 19.332 1.00 81.89 ? 84 GLN J N 1 +ATOM 17786 C CA . GLN J 1 84 ? 50.984 22.574 20.032 1.00 110.77 ? 84 GLN J CA 1 +ATOM 17787 C C . GLN J 1 84 ? 49.531 22.113 20.029 1.00 97.20 ? 84 GLN J C 1 +ATOM 17788 O O . GLN J 1 84 ? 48.856 22.179 21.032 1.00 96.95 ? 84 GLN J O 1 +ATOM 17789 C CB . GLN J 1 84 ? 51.103 23.993 19.448 1.00 102.33 ? 84 GLN J CB 1 +ATOM 17790 C CG . GLN J 1 84 ? 50.891 25.114 20.462 1.00 82.05 ? 84 GLN J CG 1 +ATOM 17791 C CD . GLN J 1 84 ? 50.890 26.485 19.798 1.00 94.01 ? 84 GLN J CD 1 +ATOM 17792 O OE1 . GLN J 1 84 ? 51.682 26.757 18.890 1.00 76.66 ? 84 GLN J OE1 1 +ATOM 17793 N NE2 . GLN J 1 84 ? 50.067 27.391 20.317 1.00 121.52 ? 84 GLN J NE2 1 +ATOM 17794 N N . GLY J 1 85 ? 49.082 21.538 18.937 1.00 87.36 ? 85 GLY J N 1 +ATOM 17795 C CA . GLY J 1 85 ? 47.718 21.024 18.922 1.00 92.38 ? 85 GLY J CA 1 +ATOM 17796 C C . GLY J 1 85 ? 47.621 19.512 18.900 1.00 85.20 ? 85 GLY J C 1 +ATOM 17797 O O . GLY J 1 85 ? 46.813 18.961 18.137 1.00 88.00 ? 85 GLY J O 1 +ATOM 17798 N N . LEU J 1 86 ? 48.498 18.831 19.646 1.00 66.43 ? 86 LEU J N 1 +ATOM 17799 C CA . LEU J 1 86 ? 48.733 17.384 19.426 1.00 70.20 ? 86 LEU J CA 1 +ATOM 17800 C C . LEU J 1 86 ? 47.463 16.584 19.645 1.00 78.88 ? 86 LEU J C 1 +ATOM 17801 O O . LEU J 1 86 ? 47.199 15.600 18.933 1.00 73.73 ? 86 LEU J O 1 +ATOM 17802 C CB . LEU J 1 86 ? 49.815 16.850 20.354 1.00 75.38 ? 86 LEU J CB 1 +ATOM 17803 C CG . LEU J 1 86 ? 50.065 15.326 20.449 1.00 70.26 ? 86 LEU J CG 1 +ATOM 17804 C CD1 . LEU J 1 86 ? 50.479 14.700 19.143 1.00 58.61 ? 86 LEU J CD1 1 +ATOM 17805 C CD2 . LEU J 1 86 ? 51.149 15.075 21.503 1.00 97.71 ? 86 LEU J CD2 1 +ATOM 17806 N N . GLN J 1 87 ? 46.622 17.077 20.542 1.00 86.02 ? 87 GLN J N 1 +ATOM 17807 C CA . GLN J 1 87 ? 45.411 16.361 20.875 1.00 105.09 ? 87 GLN J CA 1 +ATOM 17808 C C . GLN J 1 87 ? 44.480 16.205 19.644 1.00 108.85 ? 87 GLN J C 1 +ATOM 17809 O O . GLN J 1 87 ? 43.904 15.122 19.395 1.00 86.67 ? 87 GLN J O 1 +ATOM 17810 C CB . GLN J 1 87 ? 44.715 17.052 22.056 1.00 104.23 ? 87 GLN J CB 1 +ATOM 17811 C CG . GLN J 1 87 ? 44.012 16.080 22.999 1.00 116.42 ? 87 GLN J CG 1 +ATOM 17812 C CD . GLN J 1 87 ? 44.829 14.815 23.302 1.00 109.29 ? 87 GLN J CD 1 +ATOM 17813 O OE1 . GLN J 1 87 ? 45.955 14.889 23.795 1.00 95.48 ? 87 GLN J OE1 1 +ATOM 17814 N NE2 . GLN J 1 87 ? 44.244 13.650 23.036 1.00 105.49 ? 87 GLN J NE2 1 +ATOM 17815 N N . ASN J 1 88 ? 44.327 17.290 18.880 1.00 105.21 ? 88 ASN J N 1 +ATOM 17816 C CA . ASN J 1 88 ? 43.448 17.288 17.696 1.00 98.40 ? 88 ASN J CA 1 +ATOM 17817 C C . ASN J 1 88 ? 43.983 16.352 16.635 1.00 86.97 ? 88 ASN J C 1 +ATOM 17818 O O . ASN J 1 88 ? 43.245 15.727 15.884 1.00 73.47 ? 88 ASN J O 1 +ATOM 17819 C CB . ASN J 1 88 ? 43.363 18.682 17.102 1.00 97.07 ? 88 ASN J CB 1 +ATOM 17820 C CG . ASN J 1 88 ? 42.860 19.684 18.077 1.00 109.98 ? 88 ASN J CG 1 +ATOM 17821 O OD1 . ASN J 1 88 ? 41.982 19.372 18.890 1.00 163.62 ? 88 ASN J OD1 1 +ATOM 17822 N ND2 . ASN J 1 88 ? 43.428 20.891 18.048 1.00 120.26 ? 88 ASN J ND2 1 +ATOM 17823 N N . LEU J 1 89 ? 45.299 16.282 16.571 1.00 90.81 ? 89 LEU J N 1 +ATOM 17824 C CA . LEU J 1 89 ? 45.967 15.495 15.565 1.00 92.03 ? 89 LEU J CA 1 +ATOM 17825 C C . LEU J 1 89 ? 45.622 14.042 15.861 1.00 77.73 ? 89 LEU J C 1 +ATOM 17826 O O . LEU J 1 89 ? 45.326 13.257 14.941 1.00 103.14 ? 89 LEU J O 1 +ATOM 17827 C CB . LEU J 1 89 ? 47.486 15.785 15.634 1.00 120.73 ? 89 LEU J CB 1 +ATOM 17828 C CG . LEU J 1 89 ? 48.350 15.658 14.383 1.00 103.44 ? 89 LEU J CG 1 +ATOM 17829 C CD1 . LEU J 1 89 ? 49.341 14.528 14.572 1.00 113.23 ? 89 LEU J CD1 1 +ATOM 17830 C CD2 . LEU J 1 89 ? 47.503 15.412 13.150 1.00 102.80 ? 89 LEU J CD2 1 +ATOM 17831 N N . LEU J 1 90 ? 45.650 13.693 17.146 1.00 63.72 ? 90 LEU J N 1 +ATOM 17832 C CA . LEU J 1 90 ? 45.447 12.293 17.542 1.00 67.91 ? 90 LEU J CA 1 +ATOM 17833 C C . LEU J 1 90 ? 43.980 11.915 17.348 1.00 80.65 ? 90 LEU J C 1 +ATOM 17834 O O . LEU J 1 90 ? 43.643 10.771 17.060 1.00 82.12 ? 90 LEU J O 1 +ATOM 17835 C CB . LEU J 1 90 ? 45.858 12.098 18.981 1.00 52.44 ? 90 LEU J CB 1 +ATOM 17836 C CG . LEU J 1 90 ? 47.312 12.385 19.274 1.00 55.93 ? 90 LEU J CG 1 +ATOM 17837 C CD1 . LEU J 1 90 ? 47.524 12.612 20.754 1.00 64.56 ? 90 LEU J CD1 1 +ATOM 17838 C CD2 . LEU J 1 90 ? 48.137 11.211 18.783 1.00 71.24 ? 90 LEU J CD2 1 +ATOM 17839 N N . ASN J 1 91 ? 43.113 12.911 17.486 1.00 83.17 ? 91 ASN J N 1 +ATOM 17840 C CA . ASN J 1 91 ? 41.683 12.724 17.291 1.00 69.27 ? 91 ASN J CA 1 +ATOM 17841 C C . ASN J 1 91 ? 41.351 12.456 15.828 1.00 61.01 ? 91 ASN J C 1 +ATOM 17842 O O . ASN J 1 91 ? 40.642 11.522 15.512 1.00 66.38 ? 91 ASN J O 1 +ATOM 17843 C CB . ASN J 1 91 ? 40.967 13.987 17.773 1.00 94.47 ? 91 ASN J CB 1 +ATOM 17844 C CG . ASN J 1 91 ? 40.066 13.776 18.956 1.00 109.13 ? 91 ASN J CG 1 +ATOM 17845 O OD1 . ASN J 1 91 ? 40.196 12.823 19.721 1.00 121.30 ? 91 ASN J OD1 1 +ATOM 17846 N ND2 . ASN J 1 91 ? 39.149 14.716 19.126 1.00 136.54 ? 91 ASN J ND2 1 +ATOM 17847 N N . GLU J 1 92 ? 41.878 13.276 14.922 1.00 68.89 ? 92 GLU J N 1 +ATOM 17848 C CA . GLU J 1 92 ? 41.694 13.039 13.472 1.00 65.70 ? 92 GLU J CA 1 +ATOM 17849 C C . GLU J 1 92 ? 42.215 11.665 13.058 1.00 65.75 ? 92 GLU J C 1 +ATOM 17850 O O . GLU J 1 92 ? 41.618 10.987 12.219 1.00 75.60 ? 92 GLU J O 1 +ATOM 17851 C CB . GLU J 1 92 ? 42.384 14.110 12.609 1.00 57.08 ? 92 GLU J CB 1 +ATOM 17852 C CG . GLU J 1 92 ? 41.522 15.323 12.263 1.00 47.89 ? 92 GLU J CG 1 +ATOM 17853 C CD . GLU J 1 92 ? 40.188 15.001 11.624 1.00 43.27 ? 92 GLU J CD 1 +ATOM 17854 O OE1 . GLU J 1 92 ? 40.150 14.283 10.586 1.00 71.24 ? 92 GLU J OE1 1 +ATOM 17855 O OE2 . GLU J 1 92 ? 39.146 15.358 12.230 1.00 38.06 ? 92 GLU J OE2 1 +ATOM 17856 N N . ARG J 1 93 ? 43.293 11.233 13.698 1.00 65.01 ? 93 ARG J N 1 +ATOM 17857 C CA . ARG J 1 93 ? 43.843 9.911 13.438 1.00 74.78 ? 93 ARG J CA 1 +ATOM 17858 C C . ARG J 1 93 ? 42.948 8.786 14.001 1.00 74.23 ? 93 ARG J C 1 +ATOM 17859 O O . ARG J 1 93 ? 42.774 7.747 13.374 1.00 52.53 ? 93 ARG J O 1 +ATOM 17860 C CB . ARG J 1 93 ? 45.279 9.835 13.967 1.00 74.71 ? 93 ARG J CB 1 +ATOM 17861 C CG . ARG J 1 93 ? 46.246 10.720 13.164 1.00 77.96 ? 93 ARG J CG 1 +ATOM 17862 C CD . ARG J 1 93 ? 47.609 10.988 13.835 1.00 56.93 ? 93 ARG J CD 1 +ATOM 17863 N NE . ARG J 1 93 ? 48.715 10.207 13.292 1.00 47.62 ? 93 ARG J NE 1 +ATOM 17864 C CZ . ARG J 1 93 ? 49.057 9.016 13.744 1.00 57.65 ? 93 ARG J CZ 1 +ATOM 17865 N NH1 . ARG J 1 93 ? 48.480 8.481 14.845 1.00 97.68 ? 93 ARG J NH1 1 +ATOM 17866 N NH2 . ARG J 1 93 ? 50.044 8.383 13.180 1.00 51.86 ? 93 ARG J NH2 1 +ATOM 17867 N N . LYS J 1 94 ? 42.266 9.051 15.108 1.00 92.56 ? 94 LYS J N 1 +ATOM 17868 C CA . LYS J 1 94 ? 41.233 8.122 15.579 1.00 105.29 ? 94 LYS J CA 1 +ATOM 17869 C C . LYS J 1 94 ? 40.109 7.985 14.540 1.00 90.29 ? 94 LYS J C 1 +ATOM 17870 O O . LYS J 1 94 ? 39.583 6.893 14.331 1.00 66.69 ? 94 LYS J O 1 +ATOM 17871 C CB . LYS J 1 94 ? 40.640 8.595 16.913 1.00 118.59 ? 94 LYS J CB 1 +ATOM 17872 C CG . LYS J 1 94 ? 41.391 8.142 18.154 1.00 128.53 ? 94 LYS J CG 1 +ATOM 17873 C CD . LYS J 1 94 ? 40.833 8.835 19.388 1.00 135.51 ? 94 LYS J CD 1 +ATOM 17874 C CE . LYS J 1 94 ? 41.174 8.109 20.682 1.00 138.91 ? 94 LYS J CE 1 +ATOM 17875 N NZ . LYS J 1 94 ? 40.918 8.993 21.851 1.00 150.50 ? 94 LYS J NZ 1 +ATOM 17876 N N . ILE J 1 95 ? 39.702 9.116 13.960 1.00 79.27 ? 95 ILE J N 1 +ATOM 17877 C CA . ILE J 1 95 ? 38.544 9.134 13.083 1.00 82.76 ? 95 ILE J CA 1 +ATOM 17878 C C . ILE J 1 95 ? 38.881 8.426 11.803 1.00 90.42 ? 95 ILE J C 1 +ATOM 17879 O O . ILE J 1 95 ? 38.026 7.701 11.233 1.00 128.44 ? 95 ILE J O 1 +ATOM 17880 C CB . ILE J 1 95 ? 38.036 10.555 12.744 1.00 86.20 ? 95 ILE J CB 1 +ATOM 17881 C CG1 . ILE J 1 95 ? 37.867 11.400 14.022 1.00 78.98 ? 95 ILE J CG1 1 +ATOM 17882 C CG2 . ILE J 1 95 ? 36.686 10.422 12.050 1.00 82.28 ? 95 ILE J CG2 1 +ATOM 17883 C CD1 . ILE J 1 95 ? 37.070 12.671 13.847 1.00 75.33 ? 95 ILE J CD1 1 +ATOM 17884 N N . ILE J 1 96 ? 40.102 8.683 11.332 1.00 76.92 ? 96 ILE J N 1 +ATOM 17885 C CA . ILE J 1 96 ? 40.643 7.959 10.205 1.00 84.95 ? 96 ILE J CA 1 +ATOM 17886 C C . ILE J 1 96 ? 40.577 6.460 10.472 1.00 83.36 ? 96 ILE J C 1 +ATOM 17887 O O . ILE J 1 96 ? 39.969 5.714 9.696 1.00 122.95 ? 96 ILE J O 1 +ATOM 17888 C CB . ILE J 1 96 ? 42.093 8.349 9.887 1.00 88.40 ? 96 ILE J CB 1 +ATOM 17889 C CG1 . ILE J 1 96 ? 42.148 9.789 9.400 1.00 100.69 ? 96 ILE J CG1 1 +ATOM 17890 C CG2 . ILE J 1 96 ? 42.656 7.453 8.791 1.00 82.72 ? 96 ILE J CG2 1 +ATOM 17891 C CD1 . ILE J 1 96 ? 43.546 10.231 9.010 1.00 121.40 ? 96 ILE J CD1 1 +ATOM 17892 N N . ARG J 1 97 ? 41.238 6.016 11.526 1.00 77.66 ? 97 ARG J N 1 +ATOM 17893 C CA . ARG J 1 97 ? 41.345 4.585 11.793 1.00 90.96 ? 97 ARG J CA 1 +ATOM 17894 C C . ARG J 1 97 ? 39.956 3.962 11.933 1.00 93.88 ? 97 ARG J C 1 +ATOM 17895 O O . ARG J 1 97 ? 39.763 2.768 11.663 1.00 94.48 ? 97 ARG J O 1 +ATOM 17896 C CB . ARG J 1 97 ? 42.191 4.325 13.051 1.00 86.05 ? 97 ARG J CB 1 +ATOM 17897 C CG . ARG J 1 97 ? 43.598 3.837 12.776 1.00 82.07 ? 97 ARG J CG 1 +ATOM 17898 C CD . ARG J 1 97 ? 44.346 3.541 14.068 1.00 93.91 ? 97 ARG J CD 1 +ATOM 17899 N NE . ARG J 1 97 ? 44.891 4.752 14.675 1.00 98.16 ? 97 ARG J NE 1 +ATOM 17900 C CZ . ARG J 1 97 ? 46.162 5.148 14.566 1.00 108.30 ? 97 ARG J CZ 1 +ATOM 17901 N NH1 . ARG J 1 97 ? 47.060 4.441 13.871 1.00 89.42 ? 97 ARG J NH1 1 +ATOM 17902 N NH2 . ARG J 1 97 ? 46.542 6.283 15.146 1.00 125.80 ? 97 ARG J NH2 1 +ATOM 17903 N N . ALA J 1 98 ? 39.005 4.752 12.422 1.00 78.84 ? 98 ALA J N 1 +ATOM 17904 C CA . ALA J 1 98 ? 37.670 4.241 12.630 1.00 80.00 ? 98 ALA J CA 1 +ATOM 17905 C C . ALA J 1 98 ? 36.962 4.122 11.303 1.00 72.46 ? 98 ALA J C 1 +ATOM 17906 O O . ALA J 1 98 ? 36.052 3.294 11.126 1.00 72.11 ? 98 ALA J O 1 +ATOM 17907 C CB . ALA J 1 98 ? 36.907 5.146 13.584 1.00 81.51 ? 98 ALA J CB 1 +ATOM 17908 N N . ALA J 1 99 ? 37.369 4.979 10.375 1.00 72.54 ? 99 ALA J N 1 +ATOM 17909 C CA . ALA J 1 99 ? 36.775 5.019 9.030 1.00 93.95 ? 99 ALA J CA 1 +ATOM 17910 C C . ALA J 1 99 ? 37.123 3.775 8.190 1.00 81.91 ? 99 ALA J C 1 +ATOM 17911 O O . ALA J 1 99 ? 36.249 3.120 7.636 1.00 57.90 ? 99 ALA J O 1 +ATOM 17912 C CB . ALA J 1 99 ? 37.207 6.285 8.286 1.00 86.51 ? 99 ALA J CB 1 +ATOM 17913 N N . GLN J 1 100 ? 38.397 3.434 8.168 1.00 71.63 ? 100 GLN J N 1 +ATOM 17914 C CA . GLN J 1 100 ? 38.895 2.512 7.171 1.00 74.58 ? 100 GLN J CA 1 +ATOM 17915 C C . GLN J 1 100 ? 39.248 1.152 7.730 1.00 83.68 ? 100 GLN J C 1 +ATOM 17916 O O . GLN J 1 100 ? 39.823 0.317 7.028 1.00 91.21 ? 100 GLN J O 1 +ATOM 17917 C CB . GLN J 1 100 ? 40.102 3.127 6.442 1.00 98.78 ? 100 GLN J CB 1 +ATOM 17918 C CG . GLN J 1 100 ? 41.111 3.860 7.321 1.00 100.44 ? 100 GLN J CG 1 +ATOM 17919 C CD . GLN J 1 100 ? 41.867 4.962 6.574 1.00 106.82 ? 100 GLN J CD 1 +ATOM 17920 O OE1 . GLN J 1 100 ? 41.275 5.951 6.064 1.00 63.55 ? 100 GLN J OE1 1 +ATOM 17921 N NE2 . GLN J 1 100 ? 43.190 4.841 6.576 1.00 98.97 ? 100 GLN J NE2 1 +ATOM 17922 N N . GLU J 1 101 ? 38.946 0.925 9.007 1.00 101.32 ? 101 GLU J N 1 +ATOM 17923 C CA . GLU J 1 101 ? 39.284 -0.361 9.667 1.00 97.34 ? 101 GLU J CA 1 +ATOM 17924 C C . GLU J 1 101 ? 38.511 -1.566 9.090 1.00 98.78 ? 101 GLU J C 1 +ATOM 17925 O O . GLU J 1 101 ? 38.955 -2.696 9.189 1.00 62.65 ? 101 GLU J O 1 +ATOM 17926 C CB . GLU J 1 101 ? 39.073 -0.268 11.185 1.00 81.08 ? 101 GLU J CB 1 +ATOM 17927 C CG . GLU J 1 101 ? 37.699 0.246 11.600 1.00 84.43 ? 101 GLU J CG 1 +ATOM 17928 C CD . GLU J 1 101 ? 37.504 0.257 13.103 1.00 88.84 ? 101 GLU J CD 1 +ATOM 17929 O OE1 . GLU J 1 101 ? 38.515 0.154 13.826 1.00 114.48 ? 101 GLU J OE1 1 +ATOM 17930 O OE2 . GLU J 1 101 ? 36.339 0.291 13.569 1.00 87.70 ? 101 GLU J OE2 1 +ATOM 17931 N N . ASN J 1 102 ? 37.369 -1.303 8.458 1.00 112.06 ? 102 ASN J N 1 +ATOM 17932 C CA . ASN J 1 102 ? 36.536 -2.376 7.931 1.00 91.09 ? 102 ASN J CA 1 +ATOM 17933 C C . ASN J 1 102 ? 36.819 -2.696 6.478 1.00 87.48 ? 102 ASN J C 1 +ATOM 17934 O O . ASN J 1 102 ? 36.199 -3.572 5.902 1.00 74.97 ? 102 ASN J O 1 +ATOM 17935 C CB . ASN J 1 102 ? 35.064 -2.021 8.111 1.00 94.45 ? 102 ASN J CB 1 +ATOM 17936 C CG . ASN J 1 102 ? 34.630 -2.102 9.564 1.00 108.10 ? 102 ASN J CG 1 +ATOM 17937 O OD1 . ASN J 1 102 ? 34.424 -3.193 10.121 1.00 66.01 ? 102 ASN J OD1 1 +ATOM 17938 N ND2 . ASN J 1 102 ? 34.544 -0.936 10.205 1.00 115.48 ? 102 ASN J ND2 1 +ATOM 17939 N N . GLY J 1 103 ? 37.721 -1.945 5.860 1.00 116.20 ? 103 GLY J N 1 +ATOM 17940 C CA . GLY J 1 103 ? 38.019 -2.139 4.435 1.00 126.61 ? 103 GLY J CA 1 +ATOM 17941 C C . GLY J 1 103 ? 36.829 -1.973 3.493 1.00 112.33 ? 103 GLY J C 1 +ATOM 17942 O O . GLY J 1 103 ? 36.713 -2.654 2.482 1.00 95.84 ? 103 GLY J O 1 +ATOM 17943 N N . THR J 1 104 ? 35.938 -1.055 3.835 1.00 138.16 ? 104 THR J N 1 +ATOM 17944 C CA . THR J 1 104 ? 34.907 -0.643 2.914 1.00 136.94 ? 104 THR J CA 1 +ATOM 17945 C C . THR J 1 104 ? 35.288 0.678 2.272 1.00 99.48 ? 104 THR J C 1 +ATOM 17946 O O . THR J 1 104 ? 34.889 0.935 1.155 1.00 107.04 ? 104 THR J O 1 +ATOM 17947 C CB . THR J 1 104 ? 33.523 -0.530 3.604 1.00 171.84 ? 104 THR J CB 1 +ATOM 17948 O OG1 . THR J 1 104 ? 33.529 0.509 4.593 1.00 196.02 ? 104 THR J OG1 1 +ATOM 17949 C CG2 . THR J 1 104 ? 33.132 -1.859 4.266 1.00 160.60 ? 104 THR J CG2 1 +ATOM 17950 N N . VAL J 1 105 ? 36.065 1.498 2.967 1.00 78.82 ? 105 VAL J N 1 +ATOM 17951 C CA . VAL J 1 105 ? 36.329 2.838 2.493 1.00 106.05 ? 105 VAL J CA 1 +ATOM 17952 C C . VAL J 1 105 ? 36.971 2.800 1.100 1.00 132.20 ? 105 VAL J C 1 +ATOM 17953 O O . VAL J 1 105 ? 37.859 1.977 0.812 1.00 96.81 ? 105 VAL J O 1 +ATOM 17954 C CB . VAL J 1 105 ? 37.166 3.699 3.499 1.00 150.02 ? 105 VAL J CB 1 +ATOM 17955 C CG1 . VAL J 1 105 ? 38.090 4.700 2.784 1.00 178.59 ? 105 VAL J CG1 1 +ATOM 17956 C CG2 . VAL J 1 105 ? 36.252 4.459 4.458 1.00 133.59 ? 105 VAL J CG2 1 +ATOM 17957 N N . ALA J 1 106 ? 36.536 3.749 0.266 1.00 163.01 ? 106 ALA J N 1 +ATOM 17958 C CA . ALA J 1 106 ? 36.914 3.824 -1.142 1.00 150.76 ? 106 ALA J CA 1 +ATOM 17959 C C . ALA J 1 106 ? 38.417 4.036 -1.312 1.00 163.11 ? 106 ALA J C 1 +ATOM 17960 O O . ALA J 1 106 ? 39.015 4.884 -0.650 1.00 210.65 ? 106 ALA J O 1 +ATOM 17961 C CB . ALA J 1 106 ? 36.143 4.946 -1.828 1.00 130.23 ? 106 ALA J CB 1 +ATOM 17962 N N . ILE J 1 107 ? 39.018 3.257 -2.205 1.00 160.54 ? 107 ILE J N 1 +ATOM 17963 C CA . ILE J 1 107 ? 40.473 3.233 -2.377 1.00 148.58 ? 107 ILE J CA 1 +ATOM 17964 C C . ILE J 1 107 ? 41.056 4.617 -2.740 1.00 128.85 ? 107 ILE J C 1 +ATOM 17965 O O . ILE J 1 107 ? 42.190 4.942 -2.394 1.00 96.78 ? 107 ILE J O 1 +ATOM 17966 C CB . ILE J 1 107 ? 40.869 2.175 -3.437 1.00 147.25 ? 107 ILE J CB 1 +ATOM 17967 C CG1 . ILE J 1 107 ? 42.377 1.916 -3.419 1.00 137.23 ? 107 ILE J CG1 1 +ATOM 17968 C CG2 . ILE J 1 107 ? 40.411 2.600 -4.832 1.00 154.42 ? 107 ILE J CG2 1 +ATOM 17969 C CD1 . ILE J 1 107 ? 42.922 1.467 -2.078 1.00 127.06 ? 107 ILE J CD1 1 +ATOM 17970 N N . ASN J 1 108 ? 40.264 5.426 -3.434 1.00 129.88 ? 108 ASN J N 1 +ATOM 17971 C CA . ASN J 1 108 ? 40.648 6.801 -3.764 1.00 138.40 ? 108 ASN J CA 1 +ATOM 17972 C C . ASN J 1 108 ? 40.642 7.685 -2.523 1.00 140.84 ? 108 ASN J C 1 +ATOM 17973 O O . ASN J 1 108 ? 41.442 8.609 -2.394 1.00 144.86 ? 108 ASN J O 1 +ATOM 17974 C CB . ASN J 1 108 ? 39.679 7.396 -4.798 1.00 158.91 ? 108 ASN J CB 1 +ATOM 17975 C CG . ASN J 1 108 ? 39.104 6.346 -5.735 1.00 174.91 ? 108 ASN J CG 1 +ATOM 17976 O OD1 . ASN J 1 108 ? 39.697 6.032 -6.766 1.00 203.08 ? 108 ASN J OD1 1 +ATOM 17977 N ND2 . ASN J 1 108 ? 37.942 5.804 -5.381 1.00 161.55 ? 108 ASN J ND2 1 +ATOM 17978 N N . ASN J 1 109 ? 39.700 7.409 -1.633 1.00 151.95 ? 109 ASN J N 1 +ATOM 17979 C CA . ASN J 1 109 ? 39.466 8.231 -0.452 1.00 149.31 ? 109 ASN J CA 1 +ATOM 17980 C C . ASN J 1 109 ? 40.356 7.846 0.727 1.00 135.85 ? 109 ASN J C 1 +ATOM 17981 O O . ASN J 1 109 ? 40.511 8.613 1.682 1.00 130.87 ? 109 ASN J O 1 +ATOM 17982 C CB . ASN J 1 109 ? 37.993 8.135 -0.047 1.00 149.33 ? 109 ASN J CB 1 +ATOM 17983 C CG . ASN J 1 109 ? 37.284 9.463 -0.150 1.00 164.73 ? 109 ASN J CG 1 +ATOM 17984 O OD1 . ASN J 1 109 ? 36.866 10.031 0.855 1.00 210.46 ? 109 ASN J OD1 1 +ATOM 17985 N ND2 . ASN J 1 109 ? 37.183 9.992 -1.366 1.00 161.84 ? 109 ASN J ND2 1 +ATOM 17986 N N . ARG J 1 110 ? 40.938 6.651 0.644 1.00 116.43 ? 110 ARG J N 1 +ATOM 17987 C CA . ARG J 1 110 ? 41.700 6.051 1.747 1.00 99.50 ? 110 ARG J CA 1 +ATOM 17988 C C . ARG J 1 110 ? 42.826 6.989 2.202 1.00 78.23 ? 110 ARG J C 1 +ATOM 17989 O O . ARG J 1 110 ? 43.575 7.494 1.369 1.00 76.60 ? 110 ARG J O 1 +ATOM 17990 C CB . ARG J 1 110 ? 42.278 4.692 1.278 1.00 97.79 ? 110 ARG J CB 1 +ATOM 17991 C CG . ARG J 1 110 ? 42.606 3.705 2.386 1.00 102.70 ? 110 ARG J CG 1 +ATOM 17992 C CD . ARG J 1 110 ? 42.362 2.263 1.962 1.00 114.25 ? 110 ARG J CD 1 +ATOM 17993 N NE . ARG J 1 110 ? 43.537 1.651 1.325 1.00 124.18 ? 110 ARG J NE 1 +ATOM 17994 C CZ . ARG J 1 110 ? 44.178 0.563 1.775 1.00 127.44 ? 110 ARG J CZ 1 +ATOM 17995 N NH1 . ARG J 1 110 ? 43.771 -0.077 2.877 1.00 125.29 ? 110 ARG J NH1 1 +ATOM 17996 N NH2 . ARG J 1 110 ? 45.232 0.099 1.113 1.00 108.31 ? 110 ARG J NH2 1 +ATOM 17997 N N . ILE J 1 111 ? 42.988 7.158 3.509 1.00 64.71 ? 111 ILE J N 1 +ATOM 17998 C CA . ILE J 1 111 ? 44.158 7.854 4.029 1.00 73.40 ? 111 ILE J CA 1 +ATOM 17999 C C . ILE J 1 111 ? 45.132 6.901 4.690 1.00 80.36 ? 111 ILE J C 1 +ATOM 18000 O O . ILE J 1 111 ? 44.800 6.291 5.699 1.00 88.26 ? 111 ILE J O 1 +ATOM 18001 C CB . ILE J 1 111 ? 43.756 8.908 5.058 1.00 89.85 ? 111 ILE J CB 1 +ATOM 18002 C CG1 . ILE J 1 111 ? 42.871 9.968 4.377 1.00 98.41 ? 111 ILE J CG1 1 +ATOM 18003 C CG2 . ILE J 1 111 ? 45.000 9.554 5.675 1.00 93.85 ? 111 ILE J CG2 1 +ATOM 18004 C CD1 . ILE J 1 111 ? 42.166 10.924 5.325 1.00 80.87 ? 111 ILE J CD1 1 +ATOM 18005 N N . PRO J 1 112 ? 46.350 6.783 4.142 1.00 92.63 ? 112 PRO J N 1 +ATOM 18006 C CA . PRO J 1 112 ? 47.334 5.876 4.724 1.00 102.41 ? 112 PRO J CA 1 +ATOM 18007 C C . PRO J 1 112 ? 48.014 6.465 5.966 1.00 122.82 ? 112 PRO J C 1 +ATOM 18008 O O . PRO J 1 112 ? 48.482 7.613 5.933 1.00 136.73 ? 112 PRO J O 1 +ATOM 18009 C CB . PRO J 1 112 ? 48.343 5.707 3.596 1.00 109.85 ? 112 PRO J CB 1 +ATOM 18010 C CG . PRO J 1 112 ? 48.320 7.027 2.885 1.00 119.06 ? 112 PRO J CG 1 +ATOM 18011 C CD . PRO J 1 112 ? 46.943 7.614 3.078 1.00 107.95 ? 112 PRO J CD 1 +ATOM 18012 N N . LEU J 1 113 ? 48.030 5.691 7.052 1.00 148.04 ? 113 LEU J N 1 +ATOM 18013 C CA . LEU J 1 113 ? 48.484 6.174 8.354 1.00 116.51 ? 113 LEU J CA 1 +ATOM 18014 C C . LEU J 1 113 ? 49.784 5.546 8.787 1.00 87.67 ? 113 LEU J C 1 +ATOM 18015 O O . LEU J 1 113 ? 50.045 4.347 8.619 1.00 62.45 ? 113 LEU J O 1 +ATOM 18016 C CB . LEU J 1 113 ? 47.451 5.910 9.443 1.00 114.12 ? 113 LEU J CB 1 +ATOM 18017 C CG . LEU J 1 113 ? 46.364 6.973 9.595 1.00 109.10 ? 113 LEU J CG 1 +ATOM 18018 C CD1 . LEU J 1 113 ? 45.519 6.569 10.780 1.00 128.07 ? 113 LEU J CD1 1 +ATOM 18019 C CD2 . LEU J 1 113 ? 46.920 8.370 9.796 1.00 93.30 ? 113 LEU J CD2 1 +ATOM 18020 N N . GLN J 1 114 ? 50.595 6.401 9.369 1.00 93.78 ? 114 GLN J N 1 +ATOM 18021 C CA . GLN J 1 114 ? 51.968 6.089 9.628 1.00 118.07 ? 114 GLN J CA 1 +ATOM 18022 C C . GLN J 1 114 ? 52.230 6.706 10.970 1.00 105.98 ? 114 GLN J C 1 +ATOM 18023 O O . GLN J 1 114 ? 51.637 7.738 11.299 1.00 109.47 ? 114 GLN J O 1 +ATOM 18024 C CB . GLN J 1 114 ? 52.873 6.706 8.550 1.00 139.81 ? 114 GLN J CB 1 +ATOM 18025 C CG . GLN J 1 114 ? 54.140 5.906 8.254 1.00 126.25 ? 114 GLN J CG 1 +ATOM 18026 C CD . GLN J 1 114 ? 55.231 6.786 7.669 1.00 159.37 ? 114 GLN J CD 1 +ATOM 18027 O OE1 . GLN J 1 114 ? 54.935 7.823 7.061 1.00 203.84 ? 114 GLN J OE1 1 +ATOM 18028 N NE2 . GLN J 1 114 ? 56.488 6.445 7.942 1.00 142.03 ? 114 GLN J NE2 1 +ATOM 18029 N N . SER J 1 115 ? 53.098 6.064 11.740 1.00 90.96 ? 115 SER J N 1 +ATOM 18030 C CA . SER J 1 115 ? 53.383 6.496 13.083 1.00 88.64 ? 115 SER J CA 1 +ATOM 18031 C C . SER J 1 115 ? 53.827 7.962 13.061 1.00 79.41 ? 115 SER J C 1 +ATOM 18032 O O . SER J 1 115 ? 54.362 8.453 12.049 1.00 57.26 ? 115 SER J O 1 +ATOM 18033 C CB . SER J 1 115 ? 54.451 5.606 13.722 1.00 104.27 ? 115 SER J CB 1 +ATOM 18034 O OG . SER J 1 115 ? 55.616 5.504 12.891 1.00 181.75 ? 115 SER J OG 1 +ATOM 18035 N N . LEU J 1 116 ? 53.649 8.654 14.185 1.00 82.21 ? 116 LEU J N 1 +ATOM 18036 C CA . LEU J 1 116 ? 53.842 10.088 14.176 1.00 86.57 ? 116 LEU J CA 1 +ATOM 18037 C C . LEU J 1 116 ? 55.326 10.339 14.105 1.00 107.79 ? 116 LEU J C 1 +ATOM 18038 O O . LEU J 1 116 ? 56.078 9.769 14.885 1.00 112.83 ? 116 LEU J O 1 +ATOM 18039 C CB . LEU J 1 116 ? 53.265 10.754 15.412 1.00 82.19 ? 116 LEU J CB 1 +ATOM 18040 C CG . LEU J 1 116 ? 51.749 10.696 15.549 1.00 85.66 ? 116 LEU J CG 1 +ATOM 18041 C CD1 . LEU J 1 116 ? 51.324 9.482 16.412 1.00 89.21 ? 116 LEU J CD1 1 +ATOM 18042 C CD2 . LEU J 1 116 ? 51.275 12.002 16.165 1.00 71.69 ? 116 LEU J CD2 1 +ATOM 18043 N N . THR J 1 117 ? 55.741 11.119 13.108 1.00 147.82 ? 117 THR J N 1 +ATOM 18044 C CA . THR J 1 117 ? 57.150 11.455 12.905 1.00 136.59 ? 117 THR J CA 1 +ATOM 18045 C C . THR J 1 117 ? 57.680 12.085 14.165 1.00 100.62 ? 117 THR J C 1 +ATOM 18046 O O . THR J 1 117 ? 56.996 12.926 14.769 1.00 85.06 ? 117 THR J O 1 +ATOM 18047 C CB . THR J 1 117 ? 57.343 12.476 11.769 1.00 147.75 ? 117 THR J CB 1 +ATOM 18048 O OG1 . THR J 1 117 ? 56.729 11.994 10.565 1.00 152.23 ? 117 THR J OG1 1 +ATOM 18049 C CG2 . THR J 1 117 ? 58.821 12.698 11.520 1.00 150.18 ? 117 THR J CG2 1 +ATOM 18050 N N . ALA J 1 118 ? 58.849 11.626 14.598 1.00 88.60 ? 118 ALA J N 1 +ATOM 18051 C CA . ALA J 1 118 ? 59.329 11.929 15.941 1.00 97.37 ? 118 ALA J CA 1 +ATOM 18052 C C . ALA J 1 118 ? 60.577 12.769 15.862 1.00 101.44 ? 118 ALA J C 1 +ATOM 18053 O O . ALA J 1 118 ? 61.479 12.461 15.092 1.00 76.46 ? 118 ALA J O 1 +ATOM 18054 C CB . ALA J 1 118 ? 59.591 10.653 16.758 1.00 72.46 ? 118 ALA J CB 1 +ATOM 18055 N N . ALA J 1 119 ? 60.668 13.723 16.794 1.00 109.93 ? 119 ALA J N 1 +ATOM 18056 C CA . ALA J 1 119 ? 61.751 14.704 16.835 1.00 91.65 ? 119 ALA J CA 1 +ATOM 18057 C C . ALA J 1 119 ? 62.964 14.214 17.607 1.00 71.61 ? 119 ALA J C 1 +ATOM 18058 O O . ALA J 1 119 ? 62.821 13.363 18.506 1.00 72.50 ? 119 ALA J O 1 +ATOM 18059 C CB . ALA J 1 119 ? 61.239 15.985 17.455 1.00 83.74 ? 119 ALA J CB 1 +ATOM 18060 N N . ASN J 1 120 ? 64.135 14.746 17.279 1.00 66.32 ? 120 ASN J N 1 +ATOM 18061 C CA . ASN J 1 120 ? 65.317 14.405 18.049 1.00 107.04 ? 120 ASN J CA 1 +ATOM 18062 C C . ASN J 1 120 ? 65.673 15.480 19.061 1.00 121.80 ? 120 ASN J C 1 +ATOM 18063 O O . ASN J 1 120 ? 66.026 15.184 20.216 1.00 161.45 ? 120 ASN J O 1 +ATOM 18064 C CB . ASN J 1 120 ? 66.536 14.147 17.173 1.00 134.06 ? 120 ASN J CB 1 +ATOM 18065 C CG . ASN J 1 120 ? 67.758 13.702 17.998 1.00 129.07 ? 120 ASN J CG 1 +ATOM 18066 O OD1 . ASN J 1 120 ? 68.869 14.169 17.724 1.00 185.82 ? 120 ASN J OD1 1 +ATOM 18067 N ND2 . ASN J 1 120 ? 67.553 12.872 19.054 1.00 70.37 ? 120 ASN J ND2 1 +ATOM 18068 N N . ILE J 1 121 ? 65.655 16.728 18.621 1.00 99.55 ? 121 ILE J N 1 +ATOM 18069 C CA . ILE J 1 121 ? 65.858 17.814 19.558 1.00 95.89 ? 121 ILE J CA 1 +ATOM 18070 C C . ILE J 1 121 ? 64.540 18.530 19.668 1.00 95.94 ? 121 ILE J C 1 +ATOM 18071 O O . ILE J 1 121 ? 63.792 18.644 18.700 1.00 105.85 ? 121 ILE J O 1 +ATOM 18072 C CB . ILE J 1 121 ? 66.979 18.779 19.129 1.00 98.92 ? 121 ILE J CB 1 +ATOM 18073 C CG1 . ILE J 1 121 ? 66.557 19.645 17.924 1.00 113.53 ? 121 ILE J CG1 1 +ATOM 18074 C CG2 . ILE J 1 121 ? 68.259 18.011 18.824 1.00 92.91 ? 121 ILE J CG2 1 +ATOM 18075 C CD1 . ILE J 1 121 ? 66.363 21.106 18.266 1.00 111.68 ? 121 ILE J CD1 1 +ATOM 18076 N N . MET J 1 122 ? 64.213 18.967 20.869 1.00 81.37 ? 122 MET J N 1 +ATOM 18077 C CA . MET J 1 122 ? 63.089 19.862 21.004 1.00 66.99 ? 122 MET J CA 1 +ATOM 18078 C C . MET J 1 122 ? 63.556 21.142 21.665 1.00 70.50 ? 122 MET J C 1 +ATOM 18079 O O . MET J 1 122 ? 64.510 21.144 22.464 1.00 93.72 ? 122 MET J O 1 +ATOM 18080 C CB . MET J 1 122 ? 61.970 19.195 21.784 1.00 68.43 ? 122 MET J CB 1 +ATOM 18081 C CG . MET J 1 122 ? 62.348 18.686 23.173 1.00 66.73 ? 122 MET J CG 1 +ATOM 18082 S SD . MET J 1 122 ? 60.903 18.795 24.227 1.00 84.71 ? 122 MET J SD 1 +ATOM 18083 C CE . MET J 1 122 ? 61.563 19.348 25.769 1.00 73.31 ? 122 MET J CE 1 +ATOM 18084 N N . VAL J 1 123 ? 62.993 22.256 21.229 1.00 75.30 ? 123 VAL J N 1 +ATOM 18085 C CA . VAL J 1 123 ? 63.441 23.561 21.709 1.00 97.78 ? 123 VAL J CA 1 +ATOM 18086 C C . VAL J 1 123 ? 62.287 24.236 22.395 1.00 107.19 ? 123 VAL J C 1 +ATOM 18087 O O . VAL J 1 123 ? 61.225 24.391 21.824 1.00 106.13 ? 123 VAL J O 1 +ATOM 18088 C CB . VAL J 1 123 ? 63.970 24.485 20.584 1.00 119.23 ? 123 VAL J CB 1 +ATOM 18089 C CG1 . VAL J 1 123 ? 63.122 24.362 19.327 1.00 131.12 ? 123 VAL J CG1 1 +ATOM 18090 C CG2 . VAL J 1 123 ? 64.038 25.937 21.061 1.00 144.14 ? 123 VAL J CG2 1 +ATOM 18091 N N . GLU J 1 124 ? 62.513 24.649 23.633 1.00 131.47 ? 124 GLU J N 1 +ATOM 18092 C CA . GLU J 1 124 ? 61.526 25.447 24.353 1.00 119.41 ? 124 GLU J CA 1 +ATOM 18093 C C . GLU J 1 124 ? 62.170 26.691 24.909 1.00 105.25 ? 124 GLU J C 1 +ATOM 18094 O O . GLU J 1 124 ? 63.392 26.841 24.902 1.00 120.59 ? 124 GLU J O 1 +ATOM 18095 C CB . GLU J 1 124 ? 60.877 24.646 25.482 1.00 139.85 ? 124 GLU J CB 1 +ATOM 18096 C CG . GLU J 1 124 ? 61.753 23.571 26.112 1.00 146.99 ? 124 GLU J CG 1 +ATOM 18097 C CD . GLU J 1 124 ? 60.927 22.565 26.885 1.00 159.63 ? 124 GLU J CD 1 +ATOM 18098 O OE1 . GLU J 1 124 ? 59.798 22.238 26.438 1.00 123.74 ? 124 GLU J OE1 1 +ATOM 18099 O OE2 . GLU J 1 124 ? 61.410 22.119 27.945 1.00 184.57 ? 124 GLU J OE2 1 +ATOM 18100 N N . GLY J 1 125 ? 61.340 27.574 25.425 1.00 83.75 ? 125 GLY J N 1 +ATOM 18101 C CA . GLY J 1 125 ? 61.830 28.847 25.910 1.00 67.58 ? 125 GLY J CA 1 +ATOM 18102 C C . GLY J 1 125 ? 60.745 29.624 26.604 1.00 63.74 ? 125 GLY J C 1 +ATOM 18103 O O . GLY J 1 125 ? 59.695 29.082 26.970 1.00 64.95 ? 125 GLY J O 1 +ATOM 18104 N N . SER J 1 126 ? 60.950 30.928 26.712 1.00 65.26 ? 126 SER J N 1 +ATOM 18105 C CA . SER J 1 126 ? 60.014 31.765 27.430 1.00 74.75 ? 126 SER J CA 1 +ATOM 18106 C C . SER J 1 126 ? 60.195 33.200 26.983 1.00 53.18 ? 126 SER J C 1 +ATOM 18107 O O . SER J 1 126 ? 61.311 33.614 26.770 1.00 45.00 ? 126 SER J O 1 +ATOM 18108 C CB . SER J 1 126 ? 60.253 31.618 28.951 1.00 107.96 ? 126 SER J CB 1 +ATOM 18109 O OG . SER J 1 126 ? 60.735 30.319 29.328 1.00 146.61 ? 126 SER J OG 1 +ATOM 18110 N N . ILE J 1 127 ? 59.118 33.967 27.007 1.00 46.76 ? 127 ILE J N 1 +ATOM 18111 C CA . ILE J 1 127 ? 59.266 35.383 27.084 1.00 62.50 ? 127 ILE J CA 1 +ATOM 18112 C C . ILE J 1 127 ? 59.667 35.804 28.498 1.00 74.38 ? 127 ILE J C 1 +ATOM 18113 O O . ILE J 1 127 ? 58.860 35.906 29.400 1.00 77.78 ? 127 ILE J O 1 +ATOM 18114 C CB . ILE J 1 127 ? 58.000 36.126 26.664 1.00 75.54 ? 127 ILE J CB 1 +ATOM 18115 C CG1 . ILE J 1 127 ? 57.690 35.804 25.194 1.00 87.94 ? 127 ILE J CG1 1 +ATOM 18116 C CG2 . ILE J 1 127 ? 58.166 37.644 26.847 1.00 80.97 ? 127 ILE J CG2 1 +ATOM 18117 C CD1 . ILE J 1 127 ? 56.205 35.834 24.853 1.00 93.06 ? 127 ILE J CD1 1 +ATOM 18118 N N . ILE J 1 128 ? 60.957 36.078 28.667 1.00 103.37 ? 128 ILE J N 1 +ATOM 18119 C CA . ILE J 1 128 ? 61.548 36.543 29.940 1.00 82.19 ? 128 ILE J CA 1 +ATOM 18120 C C . ILE J 1 128 ? 61.515 38.076 29.896 1.00 82.16 ? 128 ILE J C 1 +ATOM 18121 O O . ILE J 1 128 ? 62.294 38.726 29.189 1.00 146.54 ? 128 ILE J O 1 +ATOM 18122 C CB . ILE J 1 128 ? 62.984 35.971 30.121 1.00 65.04 ? 128 ILE J CB 1 +ATOM 18123 C CG1 . ILE J 1 128 ? 63.877 36.296 28.909 1.00 78.93 ? 128 ILE J CG1 1 +ATOM 18124 C CG2 . ILE J 1 128 ? 62.927 34.453 30.146 1.00 64.96 ? 128 ILE J CG2 1 +ATOM 18125 C CD1 . ILE J 1 128 ? 65.356 36.293 29.223 1.00 65.81 ? 128 ILE J CD1 1 +ATOM 18126 N N . GLY J 1 129 ? 60.482 38.637 30.484 1.00 59.71 ? 129 GLY J N 1 +ATOM 18127 C CA . GLY J 1 129 ? 60.512 40.034 30.807 1.00 56.79 ? 129 GLY J CA 1 +ATOM 18128 C C . GLY J 1 129 ? 59.973 40.957 29.749 1.00 59.82 ? 129 GLY J C 1 +ATOM 18129 O O . GLY J 1 129 ? 60.275 40.852 28.534 1.00 56.68 ? 129 GLY J O 1 +ATOM 18130 N N . TYR J 1 130 ? 59.214 41.935 30.244 1.00 65.01 ? 130 TYR J N 1 +ATOM 18131 C CA . TYR J 1 130 ? 58.866 43.113 29.470 1.00 86.99 ? 130 TYR J CA 1 +ATOM 18132 C C . TYR J 1 130 ? 58.886 44.217 30.480 1.00 89.76 ? 130 TYR J C 1 +ATOM 18133 O O . TYR J 1 130 ? 58.019 44.301 31.327 1.00 83.24 ? 130 TYR J O 1 +ATOM 18134 C CB . TYR J 1 130 ? 57.471 42.978 28.799 1.00 105.90 ? 130 TYR J CB 1 +ATOM 18135 C CG . TYR J 1 130 ? 56.926 44.206 28.081 1.00 98.91 ? 130 TYR J CG 1 +ATOM 18136 C CD1 . TYR J 1 130 ? 56.527 45.340 28.800 1.00 81.40 ? 130 TYR J CD1 1 +ATOM 18137 C CD2 . TYR J 1 130 ? 56.755 44.200 26.697 1.00 99.54 ? 130 TYR J CD2 1 +ATOM 18138 C CE1 . TYR J 1 130 ? 56.029 46.448 28.159 1.00 81.19 ? 130 TYR J CE1 1 +ATOM 18139 C CE2 . TYR J 1 130 ? 56.299 45.321 26.039 1.00 104.11 ? 130 TYR J CE2 1 +ATOM 18140 C CZ . TYR J 1 130 ? 55.926 46.438 26.769 1.00 91.34 ? 130 TYR J CZ 1 +ATOM 18141 O OH . TYR J 1 130 ? 55.468 47.550 26.086 1.00 80.02 ? 130 TYR J OH 1 +ATOM 18142 N N . GLU J 1 131 ? 59.910 45.057 30.405 1.00 130.10 ? 131 GLU J N 1 +ATOM 18143 C CA . GLU J 1 131 ? 59.943 46.279 31.199 1.00 129.64 ? 131 GLU J CA 1 +ATOM 18144 C C . GLU J 1 131 ? 59.481 47.449 30.341 1.00 87.95 ? 131 GLU J C 1 +ATOM 18145 O O . GLU J 1 131 ? 59.655 47.435 29.128 1.00 61.11 ? 131 GLU J O 1 +ATOM 18146 C CB . GLU J 1 131 ? 61.353 46.504 31.724 1.00 145.68 ? 131 GLU J CB 1 +ATOM 18147 C CG . GLU J 1 131 ? 61.482 47.599 32.765 1.00 148.46 ? 131 GLU J CG 1 +ATOM 18148 C CD . GLU J 1 131 ? 61.244 47.121 34.192 1.00 148.90 ? 131 GLU J CD 1 +ATOM 18149 O OE1 . GLU J 1 131 ? 61.498 45.920 34.484 1.00 119.53 ? 131 GLU J OE1 1 +ATOM 18150 O OE2 . GLU J 1 131 ? 60.822 47.963 35.023 1.00 166.18 ? 131 GLU J OE2 1 +ATOM 18151 N N . SER J 1 132 ? 58.807 48.404 30.964 1.00 76.98 ? 132 SER J N 1 +ATOM 18152 C CA . SER J 1 132 ? 58.117 49.447 30.215 1.00 87.12 ? 132 SER J CA 1 +ATOM 18153 C C . SER J 1 132 ? 58.657 50.830 30.566 1.00 92.32 ? 132 SER J C 1 +ATOM 18154 O O . SER J 1 132 ? 58.920 51.124 31.732 1.00 109.21 ? 132 SER J O 1 +ATOM 18155 C CB . SER J 1 132 ? 56.595 49.386 30.454 1.00 85.08 ? 132 SER J CB 1 +ATOM 18156 O OG . SER J 1 132 ? 56.138 50.534 31.163 1.00 75.23 ? 132 SER J OG 1 +ATOM 18157 N N . ASN J 1 133 ? 58.742 51.696 29.562 1.00 95.39 ? 133 ASN J N 1 +ATOM 18158 C CA . ASN J 1 133 ? 59.436 52.982 29.703 1.00 93.83 ? 133 ASN J CA 1 +ATOM 18159 C C . ASN J 1 133 ? 60.776 52.800 30.390 1.00 89.88 ? 133 ASN J C 1 +ATOM 18160 O O . ASN J 1 133 ? 61.064 53.446 31.396 1.00 80.66 ? 133 ASN J O 1 +ATOM 18161 C CB . ASN J 1 133 ? 58.599 53.999 30.474 1.00 87.74 ? 133 ASN J CB 1 +ATOM 18162 C CG . ASN J 1 133 ? 57.271 54.273 29.804 1.00 116.19 ? 133 ASN J CG 1 +ATOM 18163 O OD1 . ASN J 1 133 ? 57.138 54.192 28.563 1.00 184.34 ? 133 ASN J OD1 1 +ATOM 18164 N ND2 . ASN J 1 133 ? 56.275 54.599 30.607 1.00 99.58 ? 133 ASN J ND2 1 +ATOM 18165 N N . VAL J 1 134 ? 61.599 51.937 29.803 1.00 87.86 ? 134 VAL J N 1 +ATOM 18166 C CA . VAL J 1 134 ? 62.944 51.701 30.285 1.00 98.79 ? 134 VAL J CA 1 +ATOM 18167 C C . VAL J 1 134 ? 63.768 52.976 30.079 1.00 114.76 ? 134 VAL J C 1 +ATOM 18168 O O . VAL J 1 134 ? 64.594 53.343 30.919 1.00 150.08 ? 134 VAL J O 1 +ATOM 18169 C CB . VAL J 1 134 ? 63.592 50.511 29.545 1.00 120.14 ? 134 VAL J CB 1 +ATOM 18170 C CG1 . VAL J 1 134 ? 64.965 50.194 30.120 1.00 132.70 ? 134 VAL J CG1 1 +ATOM 18171 C CG2 . VAL J 1 134 ? 62.691 49.282 29.632 1.00 140.53 ? 134 VAL J CG2 1 +ATOM 18172 N N . LYS J 1 135 ? 63.488 53.685 28.985 1.00 129.30 ? 135 LYS J N 1 +ATOM 18173 C CA . LYS J 1 135 ? 63.918 55.085 28.840 1.00 102.36 ? 135 LYS J CA 1 +ATOM 18174 C C . LYS J 1 135 ? 62.798 55.955 28.282 1.00 98.68 ? 135 LYS J C 1 +ATOM 18175 O O . LYS J 1 135 ? 61.850 55.465 27.639 1.00 108.53 ? 135 LYS J O 1 +ATOM 18176 C CB . LYS J 1 135 ? 65.132 55.175 27.921 1.00 84.65 ? 135 LYS J CB 1 +ATOM 18177 C CG . LYS J 1 135 ? 66.335 54.432 28.454 1.00 78.91 ? 135 LYS J CG 1 +ATOM 18178 C CD . LYS J 1 135 ? 67.448 54.447 27.444 1.00 84.67 ? 135 LYS J CD 1 +ATOM 18179 C CE . LYS J 1 135 ? 68.660 53.698 27.962 1.00 100.47 ? 135 LYS J CE 1 +ATOM 18180 N NZ . LYS J 1 135 ? 69.883 54.136 27.234 1.00 123.30 ? 135 LYS J NZ 1 +ATOM 18181 N N . SER J 1 136 ? 62.932 57.253 28.503 1.00 98.35 ? 136 SER J N 1 +ATOM 18182 C CA . SER J 1 136 ? 61.960 58.211 28.005 1.00 125.50 ? 136 SER J CA 1 +ATOM 18183 C C . SER J 1 136 ? 62.528 59.631 27.994 1.00 150.52 ? 136 SER J C 1 +ATOM 18184 O O . SER J 1 136 ? 63.432 59.945 28.760 1.00 162.15 ? 136 SER J O 1 +ATOM 18185 C CB . SER J 1 136 ? 60.662 58.142 28.829 1.00 109.24 ? 136 SER J CB 1 +ATOM 18186 O OG . SER J 1 136 ? 60.306 59.415 29.354 1.00 112.77 ? 136 SER J OG 1 +ATOM 18187 N N . GLY J 1 137 ? 61.965 60.488 27.144 1.00 159.04 ? 137 GLY J N 1 +ATOM 18188 C CA . GLY J 1 137 ? 62.367 61.888 27.101 1.00 173.26 ? 137 GLY J CA 1 +ATOM 18189 C C . GLY J 1 137 ? 61.443 62.777 26.289 1.00 187.09 ? 137 GLY J C 1 +ATOM 18190 O O . GLY J 1 137 ? 60.445 62.318 25.732 1.00 158.76 ? 137 GLY J O 1 +ATOM 18191 N N . GLY J 1 138 ? 61.741 64.075 26.276 1.00 199.34 ? 138 GLY J N 1 +ATOM 18192 C CA . GLY J 1 138 ? 60.929 65.041 25.544 1.00 179.69 ? 138 GLY J CA 1 +ATOM 18193 C C . GLY J 1 138 ? 61.629 66.373 25.359 1.00 171.93 ? 138 GLY J C 1 +ATOM 18194 O O . GLY J 1 138 ? 62.368 66.822 26.234 1.00 200.66 ? 138 GLY J O 1 +ATOM 18195 N N . VAL J 1 139 ? 61.382 67.007 24.215 1.00 152.92 ? 139 VAL J N 1 +ATOM 18196 C CA . VAL J 1 139 ? 61.912 68.342 23.925 1.00 117.66 ? 139 VAL J CA 1 +ATOM 18197 C C . VAL J 1 139 ? 60.865 69.208 23.225 1.00 101.62 ? 139 VAL J C 1 +ATOM 18198 O O . VAL J 1 139 ? 60.278 68.797 22.216 1.00 81.77 ? 139 VAL J O 1 +ATOM 18199 C CB . VAL J 1 139 ? 63.146 68.271 23.015 1.00 109.94 ? 139 VAL J CB 1 +ATOM 18200 C CG1 . VAL J 1 139 ? 63.587 69.677 22.640 1.00 114.06 ? 139 VAL J CG1 1 +ATOM 18201 C CG2 . VAL J 1 139 ? 64.276 67.504 23.686 1.00 102.30 ? 139 VAL J CG2 1 +ATOM 18202 N N . GLY J 1 140 ? 60.614 70.394 23.776 1.00 111.13 ? 140 GLY J N 1 +ATOM 18203 C CA . GLY J 1 140 ? 59.585 71.291 23.241 1.00 147.11 ? 140 GLY J CA 1 +ATOM 18204 C C . GLY J 1 140 ? 59.878 72.765 23.444 1.00 161.72 ? 140 GLY J C 1 +ATOM 18205 O O . GLY J 1 140 ? 60.468 73.155 24.446 1.00 177.40 ? 140 GLY J O 1 +ATOM 18206 N N . ALA J 1 141 ? 59.449 73.587 22.489 1.00 187.13 ? 141 ALA J N 1 +ATOM 18207 C CA . ALA J 1 141 ? 59.582 75.035 22.611 1.00 183.72 ? 141 ALA J CA 1 +ATOM 18208 C C . ALA J 1 141 ? 58.371 75.774 22.034 1.00 199.07 ? 141 ALA J C 1 +ATOM 18209 O O . ALA J 1 141 ? 57.805 75.380 21.014 1.00 214.56 ? 141 ALA J O 1 +ATOM 18210 C CB . ALA J 1 141 ? 60.867 75.507 21.949 1.00 140.86 ? 141 ALA J CB 1 +ATOM 18211 N N . ARG J 1 142 ? 57.949 76.822 22.728 1.00 192.68 ? 142 ARG J N 1 +ATOM 18212 C CA . ARG J 1 142 ? 56.957 77.726 22.187 1.00 171.50 ? 142 ARG J CA 1 +ATOM 18213 C C . ARG J 1 142 ? 57.488 79.149 22.264 1.00 210.24 ? 142 ARG J C 1 +ATOM 18214 O O . ARG J 1 142 ? 58.215 79.498 23.197 1.00 228.80 ? 142 ARG J O 1 +ATOM 18215 C CB . ARG J 1 142 ? 55.624 77.606 22.924 1.00 141.20 ? 142 ARG J CB 1 +ATOM 18216 C CG . ARG J 1 142 ? 54.527 78.476 22.316 1.00 145.22 ? 142 ARG J CG 1 +ATOM 18217 C CD . ARG J 1 142 ? 53.183 77.776 22.243 1.00 149.08 ? 142 ARG J CD 1 +ATOM 18218 N NE . ARG J 1 142 ? 52.442 77.889 23.495 1.00 144.91 ? 142 ARG J NE 1 +ATOM 18219 C CZ . ARG J 1 142 ? 51.502 77.043 23.901 1.00 168.42 ? 142 ARG J CZ 1 +ATOM 18220 N NH1 . ARG J 1 142 ? 51.187 75.984 23.160 1.00 200.71 ? 142 ARG J NH1 1 +ATOM 18221 N NH2 . ARG J 1 142 ? 50.887 77.242 25.062 1.00 163.35 ? 142 ARG J NH2 1 +ATOM 18222 N N . TYR J 1 143 ? 57.160 79.944 21.246 1.00 237.70 ? 143 TYR J N 1 +ATOM 18223 C CA . TYR J 1 143 ? 57.713 81.286 21.085 1.00 197.52 ? 143 TYR J CA 1 +ATOM 18224 C C . TYR J 1 143 ? 56.605 82.304 20.812 1.00 167.86 ? 143 TYR J C 1 +ATOM 18225 O O . TYR J 1 143 ? 56.313 82.658 19.670 1.00 136.35 ? 143 TYR J O 1 +ATOM 18226 C CB . TYR J 1 143 ? 58.739 81.285 19.952 1.00 187.46 ? 143 TYR J CB 1 +ATOM 18227 C CG . TYR J 1 143 ? 59.489 82.567 19.806 1.00 200.17 ? 143 TYR J CG 1 +ATOM 18228 C CD1 . TYR J 1 143 ? 60.452 82.936 20.736 1.00 198.38 ? 143 TYR J CD1 1 +ATOM 18229 C CD2 . TYR J 1 143 ? 59.247 83.412 18.738 1.00 211.03 ? 143 TYR J CD2 1 +ATOM 18230 C CE1 . TYR J 1 143 ? 61.158 84.116 20.605 1.00 186.86 ? 143 TYR J CE1 1 +ATOM 18231 C CE2 . TYR J 1 143 ? 59.951 84.595 18.593 1.00 211.80 ? 143 TYR J CE2 1 +ATOM 18232 C CZ . TYR J 1 143 ? 60.903 84.940 19.530 1.00 188.44 ? 143 TYR J CZ 1 +ATOM 18233 O OH . TYR J 1 143 ? 61.598 86.115 19.393 1.00 182.74 ? 143 TYR J OH 1 +ATOM 18234 N N . GLY J 1 145 ? 53.908 82.610 20.220 1.00 82.00 ? 145 GLY J N 1 +ATOM 18235 C CA . GLY J 1 145 ? 52.734 82.132 19.488 1.00 121.20 ? 145 GLY J CA 1 +ATOM 18236 C C . GLY J 1 145 ? 52.844 80.786 18.773 1.00 152.59 ? 145 GLY J C 1 +ATOM 18237 O O . GLY J 1 145 ? 51.841 80.077 18.637 1.00 145.68 ? 145 GLY J O 1 +ATOM 18238 N N . ILE J 1 146 ? 54.066 80.386 18.394 1.00 175.58 ? 146 ILE J N 1 +ATOM 18239 C CA . ILE J 1 146 ? 54.290 79.163 17.596 1.00 174.78 ? 146 ILE J CA 1 +ATOM 18240 C C . ILE J 1 146 ? 55.075 78.141 18.424 1.00 187.46 ? 146 ILE J C 1 +ATOM 18241 O O . ILE J 1 146 ? 56.010 78.503 19.132 1.00 241.76 ? 146 ILE J O 1 +ATOM 18242 C CB . ILE J 1 146 ? 55.075 79.458 16.295 1.00 168.08 ? 146 ILE J CB 1 +ATOM 18243 C CG1 . ILE J 1 146 ? 54.608 80.785 15.674 1.00 199.06 ? 146 ILE J CG1 1 +ATOM 18244 C CG2 . ILE J 1 146 ? 54.907 78.319 15.297 1.00 160.03 ? 146 ILE J CG2 1 +ATOM 18245 C CD1 . ILE J 1 146 ? 55.472 81.973 16.024 1.00 198.68 ? 146 ILE J CD1 1 +ATOM 18246 N N . GLY J 1 147 ? 54.677 76.872 18.377 1.00 199.26 ? 147 GLY J N 1 +ATOM 18247 C CA . GLY J 1 147 ? 55.307 75.861 19.233 1.00 194.98 ? 147 GLY J CA 1 +ATOM 18248 C C . GLY J 1 147 ? 55.332 74.451 18.682 1.00 187.53 ? 147 GLY J C 1 +ATOM 18249 O O . GLY J 1 147 ? 54.485 74.070 17.879 1.00 193.30 ? 147 GLY J O 1 +ATOM 18250 N N . ALA J 1 148 ? 56.326 73.682 19.113 1.00 171.60 ? 148 ALA J N 1 +ATOM 18251 C CA . ALA J 1 148 ? 56.405 72.276 18.771 1.00 153.47 ? 148 ALA J CA 1 +ATOM 18252 C C . ALA J 1 148 ? 57.076 71.495 19.896 1.00 164.41 ? 148 ALA J C 1 +ATOM 18253 O O . ALA J 1 148 ? 57.647 72.063 20.826 1.00 175.10 ? 148 ALA J O 1 +ATOM 18254 C CB . ALA J 1 148 ? 57.162 72.080 17.469 1.00 136.17 ? 148 ALA J CB 1 +ATOM 18255 N N . ASP J 1 149 ? 56.932 70.178 19.841 1.00 184.37 ? 149 ASP J N 1 +ATOM 18256 C CA . ASP J 1 149 ? 57.519 69.307 20.856 1.00 146.98 ? 149 ASP J CA 1 +ATOM 18257 C C . ASP J 1 149 ? 57.506 67.858 20.389 1.00 121.11 ? 149 ASP J C 1 +ATOM 18258 O O . ASP J 1 149 ? 56.607 67.443 19.647 1.00 113.81 ? 149 ASP J O 1 +ATOM 18259 C CB . ASP J 1 149 ? 56.783 69.451 22.201 1.00 147.37 ? 149 ASP J CB 1 +ATOM 18260 C CG . ASP J 1 149 ? 55.504 68.661 22.253 1.00 152.75 ? 149 ASP J CG 1 +ATOM 18261 O OD1 . ASP J 1 149 ? 54.520 69.098 21.635 1.00 189.87 ? 149 ASP J OD1 1 +ATOM 18262 O OD2 . ASP J 1 149 ? 55.483 67.609 22.910 1.00 129.25 ? 149 ASP J OD2 1 +ATOM 18263 N N . THR J 1 150 ? 58.518 67.104 20.791 1.00 114.06 ? 150 THR J N 1 +ATOM 18264 C CA . THR J 1 150 ? 58.451 65.660 20.665 1.00 135.58 ? 150 THR J CA 1 +ATOM 18265 C C . THR J 1 150 ? 58.624 65.013 22.027 1.00 151.40 ? 150 THR J C 1 +ATOM 18266 O O . THR J 1 150 ? 59.189 65.603 22.949 1.00 142.54 ? 150 THR J O 1 +ATOM 18267 C CB . THR J 1 150 ? 59.519 65.090 19.704 1.00 131.79 ? 150 THR J CB 1 +ATOM 18268 O OG1 . THR J 1 150 ? 60.820 65.431 20.179 1.00 99.49 ? 150 THR J OG1 1 +ATOM 18269 C CG2 . THR J 1 150 ? 59.312 65.617 18.300 1.00 120.50 ? 150 THR J CG2 1 +ATOM 18270 N N . GLN J 1 151 ? 58.102 63.798 22.141 1.00 168.56 ? 151 GLN J N 1 +ATOM 18271 C CA . GLN J 1 151 ? 58.246 62.995 23.329 1.00 158.98 ? 151 GLN J CA 1 +ATOM 18272 C C . GLN J 1 151 ? 58.452 61.546 22.932 1.00 142.49 ? 151 GLN J C 1 +ATOM 18273 O O . GLN J 1 151 ? 57.922 61.119 21.919 1.00 140.02 ? 151 GLN J O 1 +ATOM 18274 C CB . GLN J 1 151 ? 56.968 63.188 24.097 1.00 135.42 ? 151 GLN J CB 1 +ATOM 18275 C CG . GLN J 1 151 ? 57.054 62.829 25.557 1.00 155.40 ? 151 GLN J CG 1 +ATOM 18276 C CD . GLN J 1 151 ? 56.711 63.994 26.464 1.00 162.90 ? 151 GLN J CD 1 +ATOM 18277 O OE1 . GLN J 1 151 ? 55.667 64.623 26.303 1.00 182.46 ? 151 GLN J OE1 1 +ATOM 18278 N NE2 . GLN J 1 151 ? 57.537 64.228 27.485 1.00 141.47 ? 151 GLN J NE2 1 +ATOM 18279 N N . TYR J 1 152 ? 59.334 60.837 23.635 1.00 114.67 ? 152 TYR J N 1 +ATOM 18280 C CA . TYR J 1 152 ? 59.612 59.458 23.278 1.00 92.11 ? 152 TYR J CA 1 +ATOM 18281 C C . TYR J 1 152 ? 59.676 58.577 24.487 1.00 107.80 ? 152 TYR J C 1 +ATOM 18282 O O . TYR J 1 152 ? 60.119 59.003 25.554 1.00 133.06 ? 152 TYR J O 1 +ATOM 18283 C CB . TYR J 1 152 ? 60.891 59.346 22.451 1.00 66.62 ? 152 TYR J CB 1 +ATOM 18284 C CG . TYR J 1 152 ? 62.093 58.799 23.156 1.00 62.03 ? 152 TYR J CG 1 +ATOM 18285 C CD1 . TYR J 1 152 ? 62.717 59.507 24.194 1.00 84.13 ? 152 TYR J CD1 1 +ATOM 18286 C CD2 . TYR J 1 152 ? 62.717 57.653 22.694 1.00 56.56 ? 152 TYR J CD2 1 +ATOM 18287 C CE1 . TYR J 1 152 ? 63.888 59.030 24.803 1.00 91.11 ? 152 TYR J CE1 1 +ATOM 18288 C CE2 . TYR J 1 152 ? 63.909 57.182 23.270 1.00 69.68 ? 152 TYR J CE2 1 +ATOM 18289 C CZ . TYR J 1 152 ? 64.506 57.877 24.316 1.00 87.30 ? 152 TYR J CZ 1 +ATOM 18290 O OH . TYR J 1 152 ? 65.688 57.413 24.874 1.00 83.76 ? 152 TYR J OH 1 +ATOM 18291 N N . GLN J 1 153 ? 59.231 57.335 24.322 1.00 129.33 ? 153 GLN J N 1 +ATOM 18292 C CA . GLN J 1 153 ? 59.455 56.308 25.331 1.00 138.01 ? 153 GLN J CA 1 +ATOM 18293 C C . GLN J 1 153 ? 59.929 55.010 24.681 1.00 109.30 ? 153 GLN J C 1 +ATOM 18294 O O . GLN J 1 153 ? 59.646 54.763 23.500 1.00 156.73 ? 153 GLN J O 1 +ATOM 18295 C CB . GLN J 1 153 ? 58.166 56.079 26.114 1.00 151.56 ? 153 GLN J CB 1 +ATOM 18296 C CG . GLN J 1 153 ? 57.694 57.279 26.949 1.00 180.91 ? 153 GLN J CG 1 +ATOM 18297 C CD . GLN J 1 153 ? 56.337 57.004 27.618 1.00 211.29 ? 153 GLN J CD 1 +ATOM 18298 O OE1 . GLN J 1 153 ? 55.576 56.135 27.175 1.00 258.62 ? 153 GLN J OE1 1 +ATOM 18299 N NE2 . GLN J 1 153 ? 56.026 57.753 28.671 1.00 204.32 ? 153 GLN J NE2 1 +ATOM 18300 N N . LEU J 1 154 ? 60.687 54.210 25.422 1.00 71.09 ? 154 LEU J N 1 +ATOM 18301 C CA . LEU J 1 154 ? 61.031 52.889 24.934 1.00 91.29 ? 154 LEU J CA 1 +ATOM 18302 C C . LEU J 1 154 ? 61.026 51.803 26.012 1.00 116.16 ? 154 LEU J C 1 +ATOM 18303 O O . LEU J 1 154 ? 61.405 52.043 27.165 1.00 128.63 ? 154 LEU J O 1 +ATOM 18304 C CB . LEU J 1 154 ? 62.372 52.910 24.214 1.00 72.39 ? 154 LEU J CB 1 +ATOM 18305 C CG . LEU J 1 154 ? 63.573 53.082 25.108 1.00 86.55 ? 154 LEU J CG 1 +ATOM 18306 C CD1 . LEU J 1 154 ? 64.199 51.739 25.455 1.00 81.08 ? 154 LEU J CD1 1 +ATOM 18307 C CD2 . LEU J 1 154 ? 64.583 53.985 24.423 1.00 126.32 ? 154 LEU J CD2 1 +ATOM 18308 N N . ASP J 1 155 ? 60.662 50.592 25.571 1.00 130.47 ? 155 ASP J N 1 +ATOM 18309 C CA . ASP J 1 155 ? 60.382 49.439 26.428 1.00 93.05 ? 155 ASP J CA 1 +ATOM 18310 C C . ASP J 1 155 ? 61.311 48.291 26.033 1.00 85.78 ? 155 ASP J C 1 +ATOM 18311 O O . ASP J 1 155 ? 61.862 48.299 24.938 1.00 73.06 ? 155 ASP J O 1 +ATOM 18312 C CB . ASP J 1 155 ? 58.924 49.007 26.240 1.00 98.59 ? 155 ASP J CB 1 +ATOM 18313 C CG . ASP J 1 155 ? 57.949 50.188 26.289 1.00 104.76 ? 155 ASP J CG 1 +ATOM 18314 O OD1 . ASP J 1 155 ? 57.795 50.879 25.264 1.00 116.47 ? 155 ASP J OD1 1 +ATOM 18315 O OD2 . ASP J 1 155 ? 57.312 50.395 27.341 1.00 92.64 ? 155 ASP J OD2 1 +ATOM 18316 N N . GLN J 1 156 ? 61.475 47.306 26.912 1.00 97.81 ? 156 GLN J N 1 +ATOM 18317 C CA . GLN J 1 156 ? 62.356 46.167 26.626 1.00 90.00 ? 156 GLN J CA 1 +ATOM 18318 C C . GLN J 1 156 ? 61.584 44.863 26.594 1.00 90.38 ? 156 GLN J C 1 +ATOM 18319 O O . GLN J 1 156 ? 60.479 44.750 27.154 1.00 91.61 ? 156 GLN J O 1 +ATOM 18320 C CB . GLN J 1 156 ? 63.449 46.074 27.667 1.00 97.30 ? 156 GLN J CB 1 +ATOM 18321 C CG . GLN J 1 156 ? 64.557 45.113 27.302 1.00 107.63 ? 156 GLN J CG 1 +ATOM 18322 C CD . GLN J 1 156 ? 65.862 45.419 28.041 1.00 137.58 ? 156 GLN J CD 1 +ATOM 18323 O OE1 . GLN J 1 156 ? 65.893 46.241 28.972 1.00 132.89 ? 156 GLN J OE1 1 +ATOM 18324 N NE2 . GLN J 1 156 ? 66.941 44.725 27.661 1.00 110.91 ? 156 GLN J NE2 1 +ATOM 18325 N N . ILE J 1 157 ? 62.135 43.887 25.893 1.00 84.53 ? 157 ILE J N 1 +ATOM 18326 C CA . ILE J 1 157 ? 61.512 42.568 25.801 1.00 93.52 ? 157 ILE J CA 1 +ATOM 18327 C C . ILE J 1 157 ? 62.619 41.537 25.546 1.00 80.39 ? 157 ILE J C 1 +ATOM 18328 O O . ILE J 1 157 ? 63.577 41.810 24.836 1.00 45.51 ? 157 ILE J O 1 +ATOM 18329 C CB . ILE J 1 157 ? 60.448 42.498 24.678 1.00 95.98 ? 157 ILE J CB 1 +ATOM 18330 C CG1 . ILE J 1 157 ? 59.431 41.380 24.953 1.00 117.03 ? 157 ILE J CG1 1 +ATOM 18331 C CG2 . ILE J 1 157 ? 61.118 42.265 23.326 1.00 102.26 ? 157 ILE J CG2 1 +ATOM 18332 C CD1 . ILE J 1 157 ? 58.251 41.350 23.987 1.00 126.50 ? 157 ILE J CD1 1 +ATOM 18333 N N . ALA J 1 158 ? 62.541 40.399 26.224 1.00 89.11 ? 158 ALA J N 1 +ATOM 18334 C CA . ALA J 1 158 ? 63.631 39.437 26.150 1.00 86.40 ? 158 ALA J CA 1 +ATOM 18335 C C . ALA J 1 158 ? 63.053 38.077 25.984 1.00 68.18 ? 158 ALA J C 1 +ATOM 18336 O O . ALA J 1 158 ? 61.939 37.803 26.462 1.00 100.48 ? 158 ALA J O 1 +ATOM 18337 C CB . ALA J 1 158 ? 64.559 39.507 27.380 1.00 84.60 ? 158 ALA J CB 1 +ATOM 18338 N N . VAL J 1 159 ? 63.824 37.219 25.333 1.00 50.49 ? 159 VAL J N 1 +ATOM 18339 C CA . VAL J 1 159 ? 63.353 35.903 25.017 1.00 65.35 ? 159 VAL J CA 1 +ATOM 18340 C C . VAL J 1 159 ? 64.444 34.877 25.237 1.00 68.08 ? 159 VAL J C 1 +ATOM 18341 O O . VAL J 1 159 ? 65.564 35.038 24.770 1.00 64.16 ? 159 VAL J O 1 +ATOM 18342 C CB . VAL J 1 159 ? 62.834 35.836 23.575 1.00 90.92 ? 159 VAL J CB 1 +ATOM 18343 C CG1 . VAL J 1 159 ? 62.800 34.402 23.063 1.00 105.30 ? 159 VAL J CG1 1 +ATOM 18344 C CG2 . VAL J 1 159 ? 61.441 36.459 23.463 1.00 94.82 ? 159 VAL J CG2 1 +ATOM 18345 N N . ASN J 1 160 ? 64.102 33.823 25.984 1.00 78.15 ? 160 ASN J N 1 +ATOM 18346 C CA . ASN J 1 160 ? 64.948 32.651 26.107 1.00 67.13 ? 160 ASN J CA 1 +ATOM 18347 C C . ASN J 1 160 ? 64.482 31.599 25.117 1.00 66.52 ? 160 ASN J C 1 +ATOM 18348 O O . ASN J 1 160 ? 63.286 31.309 25.012 1.00 73.83 ? 160 ASN J O 1 +ATOM 18349 C CB . ASN J 1 160 ? 64.864 32.112 27.521 1.00 75.90 ? 160 ASN J CB 1 +ATOM 18350 C CG . ASN J 1 160 ? 65.693 30.834 27.726 1.00 120.30 ? 160 ASN J CG 1 +ATOM 18351 O OD1 . ASN J 1 160 ? 65.581 29.868 26.971 1.00 156.90 ? 160 ASN J OD1 1 +ATOM 18352 N ND2 . ASN J 1 160 ? 66.423 30.778 28.833 1.00 124.88 ? 160 ASN J ND2 1 +ATOM 18353 N N . LEU J 1 161 ? 65.414 31.088 24.331 1.00 64.03 ? 161 LEU J N 1 +ATOM 18354 C CA . LEU J 1 161 ? 65.193 29.839 23.623 1.00 71.66 ? 161 LEU J CA 1 +ATOM 18355 C C . LEU J 1 161 ? 66.281 28.833 23.994 1.00 81.63 ? 161 LEU J C 1 +ATOM 18356 O O . LEU J 1 161 ? 67.420 29.192 24.242 1.00 57.98 ? 161 LEU J O 1 +ATOM 18357 C CB . LEU J 1 161 ? 65.209 30.066 22.119 1.00 65.57 ? 161 LEU J CB 1 +ATOM 18358 C CG . LEU J 1 161 ? 64.112 30.950 21.579 1.00 69.75 ? 161 LEU J CG 1 +ATOM 18359 C CD1 . LEU J 1 161 ? 64.364 31.246 20.108 1.00 97.84 ? 161 LEU J CD1 1 +ATOM 18360 C CD2 . LEU J 1 161 ? 62.776 30.255 21.763 1.00 77.20 ? 161 LEU J CD2 1 +ATOM 18361 N N . ARG J 1 162 ? 65.939 27.558 24.008 1.00 100.17 ? 162 ARG J N 1 +ATOM 18362 C CA . ARG J 1 162 ? 66.920 26.553 24.376 1.00 117.50 ? 162 ARG J CA 1 +ATOM 18363 C C . ARG J 1 162 ? 66.656 25.168 23.795 1.00 99.06 ? 162 ARG J C 1 +ATOM 18364 O O . ARG J 1 162 ? 65.547 24.652 23.835 1.00 106.21 ? 162 ARG J O 1 +ATOM 18365 C CB . ARG J 1 162 ? 67.087 26.484 25.898 1.00 148.13 ? 162 ARG J CB 1 +ATOM 18366 C CG . ARG J 1 162 ? 65.876 26.044 26.708 1.00 160.09 ? 162 ARG J CG 1 +ATOM 18367 C CD . ARG J 1 162 ? 66.308 25.639 28.118 1.00 153.55 ? 162 ARG J CD 1 +ATOM 18368 N NE . ARG J 1 162 ? 65.229 25.029 28.901 1.00 136.85 ? 162 ARG J NE 1 +ATOM 18369 C CZ . ARG J 1 162 ? 64.284 25.705 29.562 1.00 124.23 ? 162 ARG J CZ 1 +ATOM 18370 N NH1 . ARG J 1 162 ? 64.245 27.031 29.519 1.00 123.89 ? 162 ARG J NH1 1 +ATOM 18371 N NH2 . ARG J 1 162 ? 63.347 25.044 30.225 1.00 104.70 ? 162 ARG J NH2 1 +ATOM 18372 N N . VAL J 1 163 ? 67.711 24.609 23.214 1.00 106.78 ? 163 VAL J N 1 +ATOM 18373 C CA . VAL J 1 163 ? 67.679 23.283 22.604 1.00 113.46 ? 163 VAL J CA 1 +ATOM 18374 C C . VAL J 1 163 ? 67.924 22.249 23.672 1.00 113.52 ? 163 VAL J C 1 +ATOM 18375 O O . VAL J 1 163 ? 68.993 22.219 24.279 1.00 166.00 ? 163 VAL J O 1 +ATOM 18376 C CB . VAL J 1 163 ? 68.790 23.087 21.539 1.00 99.62 ? 163 VAL J CB 1 +ATOM 18377 C CG1 . VAL J 1 163 ? 68.734 21.669 20.962 1.00 87.69 ? 163 VAL J CG1 1 +ATOM 18378 C CG2 . VAL J 1 163 ? 68.671 24.162 20.460 1.00 111.69 ? 163 VAL J CG2 1 +ATOM 18379 N N . VAL J 1 164 ? 66.978 21.336 23.793 1.00 90.54 ? 164 VAL J N 1 +ATOM 18380 C CA . VAL J 1 164 ? 67.105 20.236 24.691 1.00 80.32 ? 164 VAL J CA 1 +ATOM 18381 C C . VAL J 1 164 ? 67.280 18.994 23.858 1.00 67.15 ? 164 VAL J C 1 +ATOM 18382 O O . VAL J 1 164 ? 66.472 18.713 22.952 1.00 73.99 ? 164 VAL J O 1 +ATOM 18383 C CB . VAL J 1 164 ? 65.844 20.128 25.559 1.00 130.73 ? 164 VAL J CB 1 +ATOM 18384 C CG1 . VAL J 1 164 ? 65.930 18.929 26.499 1.00 172.61 ? 164 VAL J CG1 1 +ATOM 18385 C CG2 . VAL J 1 164 ? 65.658 21.409 26.357 1.00 124.07 ? 164 VAL J CG2 1 +ATOM 18386 N N . ASN J 1 165 ? 68.204 18.159 24.292 1.00 63.32 ? 165 ASN J N 1 +ATOM 18387 C CA . ASN J 1 165 ? 68.318 16.823 23.722 1.00 82.95 ? 165 ASN J CA 1 +ATOM 18388 C C . ASN J 1 165 ? 67.311 15.800 24.292 1.00 87.50 ? 165 ASN J C 1 +ATOM 18389 O O . ASN J 1 165 ? 67.375 15.449 25.479 1.00 87.39 ? 165 ASN J O 1 +ATOM 18390 C CB . ASN J 1 165 ? 69.727 16.276 23.936 1.00 86.00 ? 165 ASN J CB 1 +ATOM 18391 C CG . ASN J 1 165 ? 69.951 14.985 23.199 1.00 76.45 ? 165 ASN J CG 1 +ATOM 18392 O OD1 . ASN J 1 165 ? 69.229 14.687 22.219 1.00 143.97 ? 165 ASN J OD1 1 +ATOM 18393 N ND2 . ASN J 1 165 ? 71.043 14.325 23.516 1.00 64.90 ? 165 ASN J ND2 1 +ATOM 18394 N N . VAL J 1 166 ? 66.435 15.289 23.426 1.00 78.59 ? 166 VAL J N 1 +ATOM 18395 C CA . VAL J 1 166 ? 65.440 14.331 23.817 1.00 70.31 ? 166 VAL J CA 1 +ATOM 18396 C C . VAL J 1 166 ? 66.111 13.118 24.424 1.00 79.97 ? 166 VAL J C 1 +ATOM 18397 O O . VAL J 1 166 ? 65.571 12.528 25.376 1.00 159.59 ? 166 VAL J O 1 +ATOM 18398 C CB . VAL J 1 166 ? 64.581 13.912 22.613 1.00 90.66 ? 166 VAL J CB 1 +ATOM 18399 C CG1 . VAL J 1 166 ? 63.930 12.527 22.803 1.00 100.72 ? 166 VAL J CG1 1 +ATOM 18400 C CG2 . VAL J 1 166 ? 63.544 14.997 22.321 1.00 86.65 ? 166 VAL J CG2 1 +ATOM 18401 N N . SER J 1 167 ? 67.255 12.714 23.868 1.00 58.41 ? 167 SER J N 1 +ATOM 18402 C CA . SER J 1 167 ? 67.829 11.421 24.184 1.00 62.99 ? 167 SER J CA 1 +ATOM 18403 C C . SER J 1 167 ? 68.487 11.424 25.563 1.00 83.55 ? 167 SER J C 1 +ATOM 18404 O O . SER J 1 167 ? 68.763 10.341 26.136 1.00 79.44 ? 167 SER J O 1 +ATOM 18405 C CB . SER J 1 167 ? 68.837 11.018 23.120 1.00 59.18 ? 167 SER J CB 1 +ATOM 18406 O OG . SER J 1 167 ? 68.301 11.186 21.820 1.00 49.93 ? 167 SER J OG 1 +ATOM 18407 N N . THR J 1 168 ? 68.671 12.618 26.134 1.00 85.27 ? 168 THR J N 1 +ATOM 18408 C CA . THR J 1 168 ? 69.295 12.730 27.467 1.00 93.04 ? 168 THR J CA 1 +ATOM 18409 C C . THR J 1 168 ? 68.592 13.701 28.438 1.00 87.19 ? 168 THR J C 1 +ATOM 18410 O O . THR J 1 168 ? 68.643 13.540 29.663 1.00 102.15 ? 168 THR J O 1 +ATOM 18411 C CB . THR J 1 168 ? 70.761 13.158 27.311 1.00 82.51 ? 168 THR J CB 1 +ATOM 18412 O OG1 . THR J 1 168 ? 70.812 14.312 26.480 1.00 54.00 ? 168 THR J OG1 1 +ATOM 18413 C CG2 . THR J 1 168 ? 71.582 12.024 26.695 1.00 92.25 ? 168 THR J CG2 1 +ATOM 18414 N N . GLY J 1 169 ? 68.021 14.760 27.899 1.00 69.05 ? 169 GLY J N 1 +ATOM 18415 C CA . GLY J 1 169 ? 67.567 15.835 28.736 1.00 66.33 ? 169 GLY J CA 1 +ATOM 18416 C C . GLY J 1 169 ? 68.614 16.923 28.906 1.00 78.90 ? 169 GLY J C 1 +ATOM 18417 O O . GLY J 1 169 ? 68.321 17.980 29.471 1.00 109.86 ? 169 GLY J O 1 +ATOM 18418 N N . GLU J 1 170 ? 69.864 16.649 28.513 1.00 77.02 ? 170 GLU J N 1 +ATOM 18419 C CA . GLU J 1 170 ? 70.908 17.697 28.484 1.00 68.45 ? 170 GLU J CA 1 +ATOM 18420 C C . GLU J 1 170 ? 70.336 18.827 27.674 1.00 65.31 ? 170 GLU J C 1 +ATOM 18421 O O . GLU J 1 170 ? 69.870 18.625 26.548 1.00 82.68 ? 170 GLU J O 1 +ATOM 18422 C CB . GLU J 1 170 ? 72.222 17.187 27.843 1.00 74.26 ? 170 GLU J CB 1 +ATOM 18423 C CG . GLU J 1 170 ? 73.082 16.319 28.756 1.00 86.10 ? 170 GLU J CG 1 +ATOM 18424 C CD . GLU J 1 170 ? 73.799 15.155 28.058 1.00 81.41 ? 170 GLU J CD 1 +ATOM 18425 O OE1 . GLU J 1 170 ? 73.467 14.854 26.899 1.00 65.43 ? 170 GLU J OE1 1 +ATOM 18426 O OE2 . GLU J 1 170 ? 74.616 14.469 28.718 1.00 50.02 ? 170 GLU J OE2 1 +ATOM 18427 N N . ILE J 1 171 ? 70.364 20.023 28.223 1.00 62.65 ? 171 ILE J N 1 +ATOM 18428 C CA . ILE J 1 171 ? 70.207 21.185 27.388 1.00 88.50 ? 171 ILE J CA 1 +ATOM 18429 C C . ILE J 1 171 ? 71.445 21.334 26.480 1.00 98.12 ? 171 ILE J C 1 +ATOM 18430 O O . ILE J 1 171 ? 72.564 21.389 26.981 1.00 85.67 ? 171 ILE J O 1 +ATOM 18431 C CB . ILE J 1 171 ? 70.010 22.440 28.248 1.00 79.48 ? 171 ILE J CB 1 +ATOM 18432 C CG1 . ILE J 1 171 ? 68.643 22.355 28.894 1.00 91.57 ? 171 ILE J CG1 1 +ATOM 18433 C CG2 . ILE J 1 171 ? 70.123 23.685 27.382 1.00 87.12 ? 171 ILE J CG2 1 +ATOM 18434 C CD1 . ILE J 1 171 ? 68.482 23.318 30.036 1.00 104.97 ? 171 ILE J CD1 1 +ATOM 18435 N N . LEU J 1 172 ? 71.244 21.372 25.157 1.00 86.45 ? 172 LEU J N 1 +ATOM 18436 C CA . LEU J 1 172 ? 72.362 21.485 24.239 1.00 86.08 ? 172 LEU J CA 1 +ATOM 18437 C C . LEU J 1 172 ? 72.747 22.954 23.901 1.00 111.70 ? 172 LEU J C 1 +ATOM 18438 O O . LEU J 1 172 ? 73.809 23.239 23.302 1.00 101.13 ? 172 LEU J O 1 +ATOM 18439 C CB . LEU J 1 172 ? 72.092 20.693 22.955 1.00 68.38 ? 172 LEU J CB 1 +ATOM 18440 C CG . LEU J 1 172 ? 72.489 19.208 22.877 1.00 72.49 ? 172 LEU J CG 1 +ATOM 18441 C CD1 . LEU J 1 172 ? 72.478 18.647 24.266 1.00 68.44 ? 172 LEU J CD1 1 +ATOM 18442 C CD2 . LEU J 1 172 ? 71.736 18.345 21.888 1.00 93.84 ? 172 LEU J CD2 1 +ATOM 18443 N N . SER J 1 173 ? 71.868 23.885 24.261 1.00 95.00 ? 173 SER J N 1 +ATOM 18444 C CA . SER J 1 173 ? 72.100 25.306 23.991 1.00 66.24 ? 173 SER J CA 1 +ATOM 18445 C C . SER J 1 173 ? 71.035 26.166 24.642 1.00 66.01 ? 173 SER J C 1 +ATOM 18446 O O . SER J 1 173 ? 69.837 25.907 24.506 1.00 110.08 ? 173 SER J O 1 +ATOM 18447 C CB . SER J 1 173 ? 72.067 25.573 22.482 1.00 64.21 ? 173 SER J CB 1 +ATOM 18448 O OG . SER J 1 173 ? 71.935 26.956 22.225 1.00 59.56 ? 173 SER J OG 1 +ATOM 18449 N N . SER J 1 174 ? 71.456 27.210 25.321 1.00 77.85 ? 174 SER J N 1 +ATOM 18450 C CA . SER J 1 174 ? 70.520 28.228 25.807 1.00 88.90 ? 174 SER J CA 1 +ATOM 18451 C C . SER J 1 174 ? 70.960 29.561 25.263 1.00 116.09 ? 174 SER J C 1 +ATOM 18452 O O . SER J 1 174 ? 72.161 29.890 25.275 1.00 156.88 ? 174 SER J O 1 +ATOM 18453 C CB . SER J 1 174 ? 70.493 28.282 27.353 1.00 95.54 ? 174 SER J CB 1 +ATOM 18454 O OG . SER J 1 174 ? 69.448 29.098 27.858 1.00 64.76 ? 174 SER J OG 1 +ATOM 18455 N N . VAL J 1 175 ? 69.996 30.347 24.806 1.00 108.51 ? 175 VAL J N 1 +ATOM 18456 C CA . VAL J 1 175 ? 70.289 31.691 24.302 1.00 109.62 ? 175 VAL J CA 1 +ATOM 18457 C C . VAL J 1 175 ? 69.299 32.722 24.811 1.00 100.79 ? 175 VAL J C 1 +ATOM 18458 O O . VAL J 1 175 ? 68.099 32.434 24.954 1.00 159.85 ? 175 VAL J O 1 +ATOM 18459 C CB . VAL J 1 175 ? 70.300 31.720 22.758 1.00 125.58 ? 175 VAL J CB 1 +ATOM 18460 C CG1 . VAL J 1 175 ? 71.413 30.833 22.222 1.00 125.63 ? 175 VAL J CG1 1 +ATOM 18461 C CG2 . VAL J 1 175 ? 68.972 31.262 22.190 1.00 152.35 ? 175 VAL J CG2 1 +ATOM 18462 N N . ASN J 1 176 ? 69.797 33.933 25.043 1.00 86.64 ? 176 ASN J N 1 +ATOM 18463 C CA . ASN J 1 176 ? 68.997 35.007 25.629 1.00 110.89 ? 176 ASN J CA 1 +ATOM 18464 C C . ASN J 1 176 ? 68.994 36.291 24.775 1.00 102.77 ? 176 ASN J C 1 +ATOM 18465 O O . ASN J 1 176 ? 69.856 37.124 24.960 1.00 123.65 ? 176 ASN J O 1 +ATOM 18466 C CB . ASN J 1 176 ? 69.542 35.293 27.042 1.00 108.34 ? 176 ASN J CB 1 +ATOM 18467 C CG . ASN J 1 176 ? 68.741 34.573 28.134 1.00 92.37 ? 176 ASN J CG 1 +ATOM 18468 O OD1 . ASN J 1 176 ? 68.019 33.638 27.808 1.00 106.73 ? 176 ASN J OD1 1 +ATOM 18469 N ND2 . ASN J 1 176 ? 68.908 34.947 29.420 1.00 82.72 ? 176 ASN J ND2 1 +ATOM 18470 N N . THR J 1 177 ? 67.967 36.486 23.944 1.00 94.80 ? 177 THR J N 1 +ATOM 18471 C CA . THR J 1 177 ? 67.893 37.658 23.078 1.00 80.19 ? 177 THR J CA 1 +ATOM 18472 C C . THR J 1 177 ? 66.993 38.738 23.639 1.00 78.28 ? 177 THR J C 1 +ATOM 18473 O O . THR J 1 177 ? 66.189 38.486 24.544 1.00 109.61 ? 177 THR J O 1 +ATOM 18474 C CB . THR J 1 177 ? 67.366 37.290 21.689 1.00 104.45 ? 177 THR J CB 1 +ATOM 18475 O OG1 . THR J 1 177 ? 65.975 36.951 21.760 1.00 106.61 ? 177 THR J OG1 1 +ATOM 18476 C CG2 . THR J 1 177 ? 68.145 36.100 21.095 1.00 108.19 ? 177 THR J CG2 1 +ATOM 18477 N N . SER J 1 178 ? 67.163 39.953 23.139 1.00 83.55 ? 178 SER J N 1 +ATOM 18478 C CA . SER J 1 178 ? 66.475 41.122 23.688 1.00 103.70 ? 178 SER J CA 1 +ATOM 18479 C C . SER J 1 178 ? 66.190 42.124 22.598 1.00 92.36 ? 178 SER J C 1 +ATOM 18480 O O . SER J 1 178 ? 66.946 42.257 21.634 1.00 86.00 ? 178 SER J O 1 +ATOM 18481 C CB . SER J 1 178 ? 67.299 41.797 24.818 1.00 123.67 ? 178 SER J CB 1 +ATOM 18482 O OG . SER J 1 178 ? 66.789 43.091 25.144 1.00 123.38 ? 178 SER J OG 1 +ATOM 18483 N N . LYS J 1 179 ? 65.162 42.924 22.809 1.00 110.08 ? 179 LYS J N 1 +ATOM 18484 C CA . LYS J 1 179 ? 64.758 43.877 21.793 1.00 128.02 ? 179 LYS J CA 1 +ATOM 18485 C C . LYS J 1 179 ? 63.995 45.053 22.402 1.00 104.76 ? 179 LYS J C 1 +ATOM 18486 O O . LYS J 1 179 ? 63.280 44.923 23.393 1.00 131.71 ? 179 LYS J O 1 +ATOM 18487 C CB . LYS J 1 179 ? 63.893 43.148 20.773 1.00 150.26 ? 179 LYS J CB 1 +ATOM 18488 C CG . LYS J 1 179 ? 64.073 43.613 19.342 1.00 155.38 ? 179 LYS J CG 1 +ATOM 18489 C CD . LYS J 1 179 ? 63.033 44.657 18.989 1.00 123.85 ? 179 LYS J CD 1 +ATOM 18490 C CE . LYS J 1 179 ? 63.315 45.234 17.624 1.00 109.65 ? 179 LYS J CE 1 +ATOM 18491 N NZ . LYS J 1 179 ? 62.509 46.454 17.387 1.00 114.90 ? 179 LYS J NZ 1 +ATOM 18492 N N . THR J 1 180 ? 64.153 46.203 21.785 1.00 65.45 ? 180 THR J N 1 +ATOM 18493 C CA . THR J 1 180 ? 63.590 47.399 22.289 1.00 77.45 ? 180 THR J CA 1 +ATOM 18494 C C . THR J 1 180 ? 62.394 47.835 21.452 1.00 87.28 ? 180 THR J C 1 +ATOM 18495 O O . THR J 1 180 ? 62.515 47.982 20.242 1.00 81.33 ? 180 THR J O 1 +ATOM 18496 C CB . THR J 1 180 ? 64.626 48.527 22.100 1.00 86.03 ? 180 THR J CB 1 +ATOM 18497 O OG1 . THR J 1 180 ? 65.905 48.057 22.493 1.00 52.79 ? 180 THR J OG1 1 +ATOM 18498 C CG2 . THR J 1 180 ? 64.260 49.803 22.872 1.00 80.06 ? 180 THR J CG2 1 +ATOM 18499 N N . ILE J 1 181 ? 61.328 48.252 22.133 1.00 100.60 ? 181 ILE J N 1 +ATOM 18500 C CA . ILE J 1 181 ? 60.140 48.796 21.476 1.00 102.51 ? 181 ILE J CA 1 +ATOM 18501 C C . ILE J 1 181 ? 60.111 50.332 21.570 1.00 85.05 ? 181 ILE J C 1 +ATOM 18502 O O . ILE J 1 181 ? 59.998 50.899 22.659 1.00 101.98 ? 181 ILE J O 1 +ATOM 18503 C CB . ILE J 1 181 ? 58.839 48.183 22.084 1.00 109.50 ? 181 ILE J CB 1 +ATOM 18504 C CG1 . ILE J 1 181 ? 58.938 46.657 22.104 1.00 118.20 ? 181 ILE J CG1 1 +ATOM 18505 C CG2 . ILE J 1 181 ? 57.610 48.584 21.295 1.00 105.32 ? 181 ILE J CG2 1 +ATOM 18506 C CD1 . ILE J 1 181 ? 58.861 46.068 23.491 1.00 123.45 ? 181 ILE J CD1 1 +ATOM 18507 N N . LEU J 1 182 ? 60.197 50.986 20.417 1.00 78.68 ? 182 LEU J N 1 +ATOM 18508 C CA . LEU J 1 182 ? 60.173 52.451 20.337 1.00 93.25 ? 182 LEU J CA 1 +ATOM 18509 C C . LEU J 1 182 ? 58.780 53.081 20.188 1.00 98.77 ? 182 LEU J C 1 +ATOM 18510 O O . LEU J 1 182 ? 57.945 52.617 19.394 1.00 100.22 ? 182 LEU J O 1 +ATOM 18511 C CB . LEU J 1 182 ? 61.040 52.908 19.164 1.00 93.91 ? 182 LEU J CB 1 +ATOM 18512 C CG . LEU J 1 182 ? 61.127 54.428 18.944 1.00 77.65 ? 182 LEU J CG 1 +ATOM 18513 C CD1 . LEU J 1 182 ? 61.746 55.157 20.114 1.00 74.62 ? 182 LEU J CD1 1 +ATOM 18514 C CD2 . LEU J 1 182 ? 61.924 54.646 17.677 1.00 89.81 ? 182 LEU J CD2 1 +ATOM 18515 N N . SER J 1 183 ? 58.584 54.197 20.882 1.00 112.10 ? 183 SER J N 1 +ATOM 18516 C CA . SER J 1 183 ? 57.380 55.000 20.745 1.00 147.48 ? 183 SER J CA 1 +ATOM 18517 C C . SER J 1 183 ? 57.743 56.488 20.753 1.00 156.86 ? 183 SER J C 1 +ATOM 18518 O O . SER J 1 183 ? 58.590 56.920 21.527 1.00 174.20 ? 183 SER J O 1 +ATOM 18519 C CB . SER J 1 183 ? 56.399 54.686 21.885 1.00 146.05 ? 183 SER J CB 1 +ATOM 18520 O OG . SER J 1 183 ? 56.413 53.299 22.195 1.00 151.46 ? 183 SER J OG 1 +ATOM 18521 N N . TYR J 1 184 ? 57.075 57.275 19.911 1.00 166.35 ? 184 TYR J N 1 +ATOM 18522 C CA . TYR J 1 184 ? 57.267 58.731 19.902 1.00 127.93 ? 184 TYR J CA 1 +ATOM 18523 C C . TYR J 1 184 ? 56.069 59.545 19.412 1.00 109.88 ? 184 TYR J C 1 +ATOM 18524 O O . TYR J 1 184 ? 55.169 59.043 18.716 1.00 94.82 ? 184 TYR J O 1 +ATOM 18525 C CB . TYR J 1 184 ? 58.496 59.120 19.082 1.00 118.07 ? 184 TYR J CB 1 +ATOM 18526 C CG . TYR J 1 184 ? 58.453 58.698 17.639 1.00 112.95 ? 184 TYR J CG 1 +ATOM 18527 C CD1 . TYR J 1 184 ? 57.771 59.461 16.679 1.00 90.19 ? 184 TYR J CD1 1 +ATOM 18528 C CD2 . TYR J 1 184 ? 59.088 57.538 17.227 1.00 100.00 ? 184 TYR J CD2 1 +ATOM 18529 C CE1 . TYR J 1 184 ? 57.713 59.071 15.354 1.00 64.46 ? 184 TYR J CE1 1 +ATOM 18530 C CE2 . TYR J 1 184 ? 59.037 57.149 15.901 1.00 95.27 ? 184 TYR J CE2 1 +ATOM 18531 C CZ . TYR J 1 184 ? 58.361 57.929 14.973 1.00 70.30 ? 184 TYR J CZ 1 +ATOM 18532 O OH . TYR J 1 184 ? 58.240 57.473 13.685 1.00 83.68 ? 184 TYR J OH 1 +ATOM 18533 N N . GLU J 1 185 ? 56.045 60.790 19.865 1.00 115.18 ? 185 GLU J N 1 +ATOM 18534 C CA . GLU J 1 185 ? 54.914 61.673 19.687 1.00 153.73 ? 185 GLU J CA 1 +ATOM 18535 C C . GLU J 1 185 ? 55.389 63.058 19.292 1.00 186.13 ? 185 GLU J C 1 +ATOM 18536 O O . GLU J 1 185 ? 56.003 63.766 20.083 1.00 257.16 ? 185 GLU J O 1 +ATOM 18537 C CB . GLU J 1 185 ? 54.088 61.691 20.979 1.00 157.49 ? 185 GLU J CB 1 +ATOM 18538 C CG . GLU J 1 185 ? 52.977 62.720 21.075 1.00 155.27 ? 185 GLU J CG 1 +ATOM 18539 C CD . GLU J 1 185 ? 52.085 62.465 22.281 1.00 153.88 ? 185 GLU J CD 1 +ATOM 18540 O OE1 . GLU J 1 185 ? 52.310 61.464 23.001 1.00 122.83 ? 185 GLU J OE1 1 +ATOM 18541 O OE2 . GLU J 1 185 ? 51.163 63.268 22.515 1.00 170.26 ? 185 GLU J OE2 1 +ATOM 18542 N N . VAL J 1 186 ? 55.155 63.405 18.032 1.00 189.95 ? 186 VAL J N 1 +ATOM 18543 C CA . VAL J 1 186 ? 55.543 64.700 17.488 1.00 167.43 ? 186 VAL J CA 1 +ATOM 18544 C C . VAL J 1 186 ? 54.322 65.596 17.382 1.00 146.21 ? 186 VAL J C 1 +ATOM 18545 O O . VAL J 1 186 ? 53.222 65.148 17.053 1.00 131.55 ? 186 VAL J O 1 +ATOM 18546 C CB . VAL J 1 186 ? 56.165 64.564 16.092 1.00 159.45 ? 186 VAL J CB 1 +ATOM 18547 C CG1 . VAL J 1 186 ? 56.734 65.899 15.635 1.00 150.47 ? 186 VAL J CG1 1 +ATOM 18548 C CG2 . VAL J 1 186 ? 57.245 63.497 16.097 1.00 145.58 ? 186 VAL J CG2 1 +ATOM 18549 N N . GLN J 1 187 ? 54.500 66.861 17.725 1.00 133.80 ? 187 GLN J N 1 +ATOM 18550 C CA . GLN J 1 187 ? 53.364 67.731 17.826 1.00 148.24 ? 187 GLN J CA 1 +ATOM 18551 C C . GLN J 1 187 ? 53.758 69.198 17.580 1.00 155.97 ? 187 GLN J C 1 +ATOM 18552 O O . GLN J 1 187 ? 54.832 69.655 17.999 1.00 209.19 ? 187 GLN J O 1 +ATOM 18553 C CB . GLN J 1 187 ? 52.668 67.484 19.158 1.00 146.09 ? 187 GLN J CB 1 +ATOM 18554 C CG . GLN J 1 187 ? 51.515 68.411 19.399 1.00 145.00 ? 187 GLN J CG 1 +ATOM 18555 C CD . GLN J 1 187 ? 50.904 68.203 20.759 1.00 162.36 ? 187 GLN J CD 1 +ATOM 18556 O OE1 . GLN J 1 187 ? 51.596 67.836 21.702 1.00 156.17 ? 187 GLN J OE1 1 +ATOM 18557 N NE2 . GLN J 1 187 ? 49.586 68.369 20.853 1.00 182.36 ? 187 GLN J NE2 1 +ATOM 18558 N N . ALA J 1 188 ? 52.944 69.894 16.787 1.00 177.80 ? 188 ALA J N 1 +ATOM 18559 C CA . ALA J 1 188 ? 53.212 71.296 16.462 1.00 157.45 ? 188 ALA J CA 1 +ATOM 18560 C C . ALA J 1 188 ? 51.910 72.092 16.446 1.00 164.80 ? 188 ALA J C 1 +ATOM 18561 O O . ALA J 1 188 ? 50.876 71.595 16.008 1.00 164.99 ? 188 ALA J O 1 +ATOM 18562 C CB . ALA J 1 188 ? 53.927 71.411 15.123 1.00 112.49 ? 188 ALA J CB 1 +ATOM 18563 N N . GLY J 1 189 ? 51.956 73.314 16.959 1.00 176.44 ? 189 GLY J N 1 +ATOM 18564 C CA . GLY J 1 189 ? 50.784 74.175 16.982 1.00 189.17 ? 189 GLY J CA 1 +ATOM 18565 C C . GLY J 1 189 ? 51.129 75.631 16.753 1.00 210.93 ? 189 GLY J C 1 +ATOM 18566 O O . GLY J 1 189 ? 52.117 76.135 17.285 1.00 230.67 ? 189 GLY J O 1 +ATOM 18567 N N . VAL J 1 190 ? 50.308 76.307 15.957 1.00 230.42 ? 190 VAL J N 1 +ATOM 18568 C CA . VAL J 1 190 ? 50.464 77.732 15.717 1.00 209.51 ? 190 VAL J CA 1 +ATOM 18569 C C . VAL J 1 190 ? 49.263 78.487 16.311 1.00 212.22 ? 190 VAL J C 1 +ATOM 18570 O O . VAL J 1 190 ? 48.113 78.068 16.134 1.00 211.97 ? 190 VAL J O 1 +ATOM 18571 C CB . VAL J 1 190 ? 50.595 78.028 14.207 1.00 169.53 ? 190 VAL J CB 1 +ATOM 18572 C CG1 . VAL J 1 190 ? 50.997 79.474 14.000 1.00 184.86 ? 190 VAL J CG1 1 +ATOM 18573 C CG2 . VAL J 1 190 ? 51.587 77.076 13.542 1.00 117.34 ? 190 VAL J CG2 1 +ATOM 18574 N N . PHE J 1 191 ? 49.536 79.587 17.013 1.00 204.09 ? 191 PHE J N 1 +ATOM 18575 C CA . PHE J 1 191 ? 48.508 80.303 17.781 1.00 215.39 ? 191 PHE J CA 1 +ATOM 18576 C C . PHE J 1 191 ? 48.631 81.835 17.605 1.00 243.62 ? 191 PHE J C 1 +ATOM 18577 O O . PHE J 1 191 ? 49.708 82.361 17.601 1.00 234.13 ? 191 PHE J O 1 +ATOM 18578 C CB . PHE J 1 191 ? 48.666 79.965 19.271 1.00 190.97 ? 191 PHE J CB 1 +ATOM 18579 C CG . PHE J 1 191 ? 47.419 80.215 20.095 1.00 186.08 ? 191 PHE J CG 1 +ATOM 18580 C CD1 . PHE J 1 191 ? 47.019 81.509 20.407 1.00 160.96 ? 191 PHE J CD1 1 +ATOM 18581 C CD2 . PHE J 1 191 ? 46.661 79.161 20.574 1.00 188.02 ? 191 PHE J CD2 1 +ATOM 18582 C CE1 . PHE J 1 191 ? 45.877 81.750 21.154 1.00 135.41 ? 191 PHE J CE1 1 +ATOM 18583 C CE2 . PHE J 1 191 ? 45.532 79.396 21.346 1.00 171.05 ? 191 PHE J CE2 1 +ATOM 18584 C CZ . PHE J 1 191 ? 45.139 80.692 21.633 1.00 145.27 ? 191 PHE J CZ 1 +ATOM 18585 N N . ARG J 1 192 ? 47.523 82.570 17.536 1.00 236.62 ? 192 ARG J N 1 +ATOM 18586 C CA . ARG J 1 192 ? 47.564 84.047 17.505 1.00 182.76 ? 192 ARG J CA 1 +ATOM 18587 C C . ARG J 1 192 ? 46.243 84.650 17.994 1.00 146.16 ? 192 ARG J C 1 +ATOM 18588 O O . ARG J 1 192 ? 46.179 85.818 18.360 1.00 114.71 ? 192 ARG J O 1 +ATOM 18589 C CB . ARG J 1 192 ? 47.904 84.544 16.085 1.00 167.67 ? 192 ARG J CB 1 +ATOM 18590 C CG . ARG J 1 192 ? 49.362 84.942 15.873 1.00 143.89 ? 192 ARG J CG 1 +ATOM 18591 C CD . ARG J 1 192 ? 49.888 84.518 14.517 1.00 128.27 ? 192 ARG J CD 1 +ATOM 18592 N NE . ARG J 1 192 ? 51.342 84.495 14.540 1.00 140.65 ? 192 ARG J NE 1 +ATOM 18593 C CZ . ARG J 1 192 ? 52.105 83.512 14.065 1.00 146.55 ? 192 ARG J CZ 1 +ATOM 18594 N NH1 . ARG J 1 192 ? 51.563 82.490 13.420 1.00 162.43 ? 192 ARG J NH1 1 +ATOM 18595 N NH2 . ARG J 1 192 ? 53.431 83.615 14.143 1.00 146.38 ? 192 ARG J NH2 1 +ATOM 18596 N N . LEU J 1 200 ? 43.649 82.950 15.765 1.00 96.81 ? 200 LEU J N 1 +ATOM 18597 C CA . LEU J 1 200 ? 43.883 81.911 14.770 1.00 125.38 ? 200 LEU J CA 1 +ATOM 18598 C C . LEU J 1 200 ? 44.731 80.780 15.343 1.00 166.07 ? 200 LEU J C 1 +ATOM 18599 O O . LEU J 1 200 ? 45.900 80.974 15.675 1.00 215.46 ? 200 LEU J O 1 +ATOM 18600 C CB . LEU J 1 200 ? 44.561 82.499 13.531 1.00 123.09 ? 200 LEU J CB 1 +ATOM 18601 C CG . LEU J 1 200 ? 45.448 81.547 12.726 1.00 134.98 ? 200 LEU J CG 1 +ATOM 18602 C CD1 . LEU J 1 200 ? 45.516 81.977 11.269 1.00 123.01 ? 200 LEU J CD1 1 +ATOM 18603 C CD2 . LEU J 1 200 ? 46.841 81.469 13.332 1.00 126.32 ? 200 LEU J CD2 1 +ATOM 18604 N N . GLU J 1 201 ? 44.133 79.598 15.456 1.00 187.72 ? 201 GLU J N 1 +ATOM 18605 C CA . GLU J 1 201 ? 44.833 78.431 15.990 1.00 195.67 ? 201 GLU J CA 1 +ATOM 18606 C C . GLU J 1 201 ? 44.947 77.351 14.921 1.00 207.57 ? 201 GLU J C 1 +ATOM 18607 O O . GLU J 1 201 ? 44.077 77.230 14.065 1.00 181.52 ? 201 GLU J O 1 +ATOM 18608 C CB . GLU J 1 201 ? 44.107 77.862 17.208 1.00 185.27 ? 201 GLU J CB 1 +ATOM 18609 C CG . GLU J 1 201 ? 44.997 76.968 18.062 1.00 173.15 ? 201 GLU J CG 1 +ATOM 18610 C CD . GLU J 1 201 ? 44.278 76.390 19.271 1.00 178.65 ? 201 GLU J CD 1 +ATOM 18611 O OE1 . GLU J 1 201 ? 43.662 77.170 20.038 1.00 206.62 ? 201 GLU J OE1 1 +ATOM 18612 O OE2 . GLU J 1 201 ? 44.380 75.168 19.497 1.00 136.30 ? 201 GLU J OE2 1 +ATOM 18613 N N . GLY J 1 202 ? 46.038 76.593 14.964 1.00 221.25 ? 202 GLY J N 1 +ATOM 18614 C CA . GLY J 1 202 ? 46.209 75.435 14.088 1.00 214.74 ? 202 GLY J CA 1 +ATOM 18615 C C . GLY J 1 202 ? 47.149 74.412 14.694 1.00 216.14 ? 202 GLY J C 1 +ATOM 18616 O O . GLY J 1 202 ? 48.265 74.749 15.091 1.00 240.32 ? 202 GLY J O 1 +ATOM 18617 N N . GLU J 1 203 ? 46.692 73.166 14.803 1.00 201.51 ? 203 GLU J N 1 +ATOM 18618 C CA . GLU J 1 203 ? 47.476 72.125 15.463 1.00 165.46 ? 203 GLU J CA 1 +ATOM 18619 C C . GLU J 1 203 ? 47.595 70.845 14.639 1.00 138.12 ? 203 GLU J C 1 +ATOM 18620 O O . GLU J 1 203 ? 46.616 70.348 14.076 1.00 109.25 ? 203 GLU J O 1 +ATOM 18621 C CB . GLU J 1 203 ? 46.882 71.795 16.832 1.00 177.15 ? 203 GLU J CB 1 +ATOM 18622 C CG . GLU J 1 203 ? 46.985 72.947 17.832 1.00 180.02 ? 203 GLU J CG 1 +ATOM 18623 C CD . GLU J 1 203 ? 46.479 72.613 19.229 1.00 164.14 ? 203 GLU J CD 1 +ATOM 18624 O OE1 . GLU J 1 203 ? 45.926 71.506 19.414 1.00 140.75 ? 203 GLU J OE1 1 +ATOM 18625 O OE2 . GLU J 1 203 ? 46.647 73.458 20.137 1.00 136.89 ? 203 GLU J OE2 1 +ATOM 18626 N N . VAL J 1 204 ? 48.817 70.331 14.581 1.00 129.95 ? 204 VAL J N 1 +ATOM 18627 C CA . VAL J 1 204 ? 49.105 69.057 13.941 1.00 132.65 ? 204 VAL J CA 1 +ATOM 18628 C C . VAL J 1 204 ? 49.804 68.160 14.954 1.00 174.71 ? 204 VAL J C 1 +ATOM 18629 O O . VAL J 1 204 ? 50.693 68.602 15.696 1.00 232.78 ? 204 VAL J O 1 +ATOM 18630 C CB . VAL J 1 204 ? 49.994 69.249 12.693 1.00 114.98 ? 204 VAL J CB 1 +ATOM 18631 C CG1 . VAL J 1 204 ? 50.637 67.936 12.246 1.00 109.99 ? 204 VAL J CG1 1 +ATOM 18632 C CG2 . VAL J 1 204 ? 49.171 69.865 11.570 1.00 97.91 ? 204 VAL J CG2 1 +ATOM 18633 N N . GLY J 1 205 ? 49.388 66.899 14.991 1.00 202.41 ? 205 GLY J N 1 +ATOM 18634 C CA . GLY J 1 205 ? 50.013 65.909 15.859 1.00 200.96 ? 205 GLY J CA 1 +ATOM 18635 C C . GLY J 1 205 ? 50.213 64.576 15.148 1.00 185.91 ? 205 GLY J C 1 +ATOM 18636 O O . GLY J 1 205 ? 49.447 64.213 14.253 1.00 147.54 ? 205 GLY J O 1 +ATOM 18637 N N . TYR J 1 206 ? 51.248 63.847 15.550 1.00 168.41 ? 206 TYR J N 1 +ATOM 18638 C CA . TYR J 1 206 ? 51.487 62.497 15.044 1.00 147.64 ? 206 TYR J CA 1 +ATOM 18639 C C . TYR J 1 206 ? 52.122 61.641 16.123 1.00 170.66 ? 206 TYR J C 1 +ATOM 18640 O O . TYR J 1 206 ? 52.954 62.122 16.882 1.00 190.65 ? 206 TYR J O 1 +ATOM 18641 C CB . TYR J 1 206 ? 52.413 62.531 13.836 1.00 131.52 ? 206 TYR J CB 1 +ATOM 18642 C CG . TYR J 1 206 ? 52.758 61.151 13.320 1.00 127.77 ? 206 TYR J CG 1 +ATOM 18643 C CD1 . TYR J 1 206 ? 51.823 60.394 12.584 1.00 114.89 ? 206 TYR J CD1 1 +ATOM 18644 C CD2 . TYR J 1 206 ? 54.014 60.601 13.565 1.00 123.23 ? 206 TYR J CD2 1 +ATOM 18645 C CE1 . TYR J 1 206 ? 52.147 59.154 12.072 1.00 108.17 ? 206 TYR J CE1 1 +ATOM 18646 C CE2 . TYR J 1 206 ? 54.344 59.354 13.071 1.00 145.87 ? 206 TYR J CE2 1 +ATOM 18647 C CZ . TYR J 1 206 ? 53.409 58.639 12.327 1.00 151.76 ? 206 TYR J CZ 1 +ATOM 18648 O OH . TYR J 1 206 ? 53.762 57.395 11.858 1.00 213.80 ? 206 TYR J OH 1 +ATOM 18649 N N . THR J 1 207 ? 51.730 60.371 16.193 1.00 177.87 ? 207 THR J N 1 +ATOM 18650 C CA . THR J 1 207 ? 52.297 59.447 17.179 1.00 152.48 ? 207 THR J CA 1 +ATOM 18651 C C . THR J 1 207 ? 52.567 58.071 16.565 1.00 129.58 ? 207 THR J C 1 +ATOM 18652 O O . THR J 1 207 ? 51.755 57.560 15.780 1.00 110.63 ? 207 THR J O 1 +ATOM 18653 C CB . THR J 1 207 ? 51.357 59.261 18.388 1.00 157.65 ? 207 THR J CB 1 +ATOM 18654 O OG1 . THR J 1 207 ? 50.117 58.692 17.955 1.00 145.29 ? 207 THR J OG1 1 +ATOM 18655 C CG2 . THR J 1 207 ? 51.077 60.582 19.069 1.00 151.43 ? 207 THR J CG2 1 +ATOM 18656 N N . SER J 1 208 ? 53.718 57.486 16.900 1.00 100.15 ? 208 SER J N 1 +ATOM 18657 C CA . SER J 1 208 ? 54.070 56.167 16.375 1.00 101.85 ? 208 SER J CA 1 +ATOM 18658 C C . SER J 1 208 ? 54.577 55.239 17.452 1.00 97.33 ? 208 SER J C 1 +ATOM 18659 O O . SER J 1 208 ? 55.523 55.564 18.155 1.00 99.44 ? 208 SER J O 1 +ATOM 18660 C CB . SER J 1 208 ? 55.104 56.266 15.248 1.00 104.89 ? 208 SER J CB 1 +ATOM 18661 O OG . SER J 1 208 ? 55.563 54.976 14.845 1.00 109.05 ? 208 SER J OG 1 +ATOM 18662 N N . ASN J 1 209 ? 53.941 54.071 17.539 1.00 131.41 ? 209 ASN J N 1 +ATOM 18663 C CA . ASN J 1 209 ? 54.385 52.975 18.394 1.00 122.18 ? 209 ASN J CA 1 +ATOM 18664 C C . ASN J 1 209 ? 54.856 51.801 17.560 1.00 113.24 ? 209 ASN J C 1 +ATOM 18665 O O . ASN J 1 209 ? 54.202 51.426 16.577 1.00 152.50 ? 209 ASN J O 1 +ATOM 18666 C CB . ASN J 1 209 ? 53.238 52.485 19.276 1.00 102.32 ? 209 ASN J CB 1 +ATOM 18667 C CG . ASN J 1 209 ? 52.846 53.491 20.322 1.00 88.62 ? 209 ASN J CG 1 +ATOM 18668 O OD1 . ASN J 1 209 ? 53.490 53.597 21.366 1.00 133.16 ? 209 ASN J OD1 1 +ATOM 18669 N ND2 . ASN J 1 209 ? 51.815 54.240 20.047 1.00 66.42 ? 209 ASN J ND2 1 +ATOM 18670 N N . GLU J 1 210 ? 55.984 51.226 17.943 1.00 82.25 ? 210 GLU J N 1 +ATOM 18671 C CA . GLU J 1 210 ? 56.370 49.949 17.377 1.00 93.45 ? 210 GLU J CA 1 +ATOM 18672 C C . GLU J 1 210 ? 55.376 48.907 17.845 1.00 101.77 ? 210 GLU J C 1 +ATOM 18673 O O . GLU J 1 210 ? 54.917 48.936 18.985 1.00 122.61 ? 210 GLU J O 1 +ATOM 18674 C CB . GLU J 1 210 ? 57.779 49.573 17.820 1.00 107.69 ? 210 GLU J CB 1 +ATOM 18675 C CG . GLU J 1 210 ? 58.673 49.012 16.733 1.00 128.11 ? 210 GLU J CG 1 +ATOM 18676 C CD . GLU J 1 210 ? 60.150 49.053 17.119 1.00 173.49 ? 210 GLU J CD 1 +ATOM 18677 O OE1 . GLU J 1 210 ? 60.585 49.934 17.926 1.00 194.35 ? 210 GLU J OE1 1 +ATOM 18678 O OE2 . GLU J 1 210 ? 60.904 48.227 16.566 1.00 254.05 ? 210 GLU J OE2 1 +ATOM 18679 N N . PRO J 1 211 ? 55.031 47.965 16.968 1.00 137.14 ? 211 PRO J N 1 +ATOM 18680 C CA . PRO J 1 211 ? 54.244 46.828 17.431 1.00 161.86 ? 211 PRO J CA 1 +ATOM 18681 C C . PRO J 1 211 ? 55.056 45.851 18.297 1.00 176.29 ? 211 PRO J C 1 +ATOM 18682 O O . PRO J 1 211 ? 56.125 45.385 17.877 1.00 175.64 ? 211 PRO J O 1 +ATOM 18683 C CB . PRO J 1 211 ? 53.804 46.150 16.127 1.00 171.79 ? 211 PRO J CB 1 +ATOM 18684 C CG . PRO J 1 211 ? 54.010 47.168 15.058 1.00 142.11 ? 211 PRO J CG 1 +ATOM 18685 C CD . PRO J 1 211 ? 55.202 47.947 15.510 1.00 147.47 ? 211 PRO J CD 1 +ATOM 18686 N N . VAL J 1 212 ? 54.540 45.550 19.489 1.00 136.46 ? 212 VAL J N 1 +ATOM 18687 C CA . VAL J 1 212 ? 55.217 44.653 20.425 1.00 109.08 ? 212 VAL J CA 1 +ATOM 18688 C C . VAL J 1 212 ? 55.242 43.288 19.793 1.00 91.60 ? 212 VAL J C 1 +ATOM 18689 O O . VAL J 1 212 ? 56.217 42.532 19.882 1.00 75.69 ? 212 VAL J O 1 +ATOM 18690 C CB . VAL J 1 212 ? 54.470 44.589 21.773 1.00 93.72 ? 212 VAL J CB 1 +ATOM 18691 C CG1 . VAL J 1 212 ? 55.261 43.734 22.762 1.00 92.40 ? 212 VAL J CG1 1 +ATOM 18692 C CG2 . VAL J 1 212 ? 54.259 45.993 22.352 1.00 128.12 ? 212 VAL J CG2 1 +ATOM 18693 N N . MET J 1 213 ? 54.111 42.979 19.179 1.00 88.55 ? 213 MET J N 1 +ATOM 18694 C CA . MET J 1 213 ? 53.925 41.829 18.272 1.00 104.75 ? 213 MET J CA 1 +ATOM 18695 C C . MET J 1 213 ? 55.134 41.547 17.364 1.00 85.31 ? 213 MET J C 1 +ATOM 18696 O O . MET J 1 213 ? 55.661 40.439 17.303 1.00 56.45 ? 213 MET J O 1 +ATOM 18697 C CB . MET J 1 213 ? 52.700 42.213 17.443 1.00 137.61 ? 213 MET J CB 1 +ATOM 18698 C CG . MET J 1 213 ? 52.171 41.223 16.449 1.00 180.56 ? 213 MET J CG 1 +ATOM 18699 S SD . MET J 1 213 ? 50.750 42.056 15.655 1.00 204.02 ? 213 MET J SD 1 +ATOM 18700 C CE . MET J 1 213 ? 51.497 42.235 14.054 1.00 206.58 ? 213 MET J CE 1 +ATOM 18701 N N . LEU J 1 214 ? 55.631 42.614 16.769 1.00 111.73 ? 214 LEU J N 1 +ATOM 18702 C CA . LEU J 1 214 ? 56.577 42.515 15.678 1.00 136.20 ? 214 LEU J CA 1 +ATOM 18703 C C . LEU J 1 214 ? 57.963 42.425 16.260 1.00 120.55 ? 214 LEU J C 1 +ATOM 18704 O O . LEU J 1 214 ? 58.865 41.837 15.663 1.00 137.40 ? 214 LEU J O 1 +ATOM 18705 C CB . LEU J 1 214 ? 56.438 43.743 14.752 1.00 186.47 ? 214 LEU J CB 1 +ATOM 18706 C CG . LEU J 1 214 ? 56.479 43.543 13.232 1.00 210.21 ? 214 LEU J CG 1 +ATOM 18707 C CD1 . LEU J 1 214 ? 55.372 42.608 12.741 1.00 246.85 ? 214 LEU J CD1 1 +ATOM 18708 C CD2 . LEU J 1 214 ? 56.378 44.892 12.526 1.00 192.32 ? 214 LEU J CD2 1 +ATOM 18709 N N . CYS J 1 215 ? 58.138 43.039 17.423 1.00 116.26 ? 215 CYS J N 1 +ATOM 18710 C CA . CYS J 1 215 ? 59.420 42.996 18.123 1.00 151.59 ? 215 CYS J CA 1 +ATOM 18711 C C . CYS J 1 215 ? 59.659 41.602 18.691 1.00 152.87 ? 215 CYS J C 1 +ATOM 18712 O O . CYS J 1 215 ? 60.800 41.076 18.684 1.00 114.03 ? 215 CYS J O 1 +ATOM 18713 C CB . CYS J 1 215 ? 59.438 44.017 19.260 1.00 159.76 ? 215 CYS J CB 1 +ATOM 18714 S SG . CYS J 1 215 ? 59.338 45.727 18.711 1.00 146.81 ? 215 CYS J SG 1 +ATOM 18715 N N . LEU J 1 216 ? 58.587 41.028 19.238 1.00 136.01 ? 216 LEU J N 1 +ATOM 18716 C CA . LEU J 1 216 ? 58.646 39.668 19.740 1.00 132.86 ? 216 LEU J CA 1 +ATOM 18717 C C . LEU J 1 216 ? 59.078 38.741 18.606 1.00 137.74 ? 216 LEU J C 1 +ATOM 18718 O O . LEU J 1 216 ? 60.008 37.934 18.761 1.00 129.96 ? 216 LEU J O 1 +ATOM 18719 C CB . LEU J 1 216 ? 57.298 39.246 20.297 1.00 114.34 ? 216 LEU J CB 1 +ATOM 18720 C CG . LEU J 1 216 ? 57.241 37.793 20.790 1.00 118.95 ? 216 LEU J CG 1 +ATOM 18721 C CD1 . LEU J 1 216 ? 58.264 37.493 21.869 1.00 104.82 ? 216 LEU J CD1 1 +ATOM 18722 C CD2 . LEU J 1 216 ? 55.838 37.484 21.305 1.00 132.65 ? 216 LEU J CD2 1 +ATOM 18723 N N . MET J 1 217 ? 58.467 38.935 17.436 1.00 121.81 ? 217 MET J N 1 +ATOM 18724 C CA . MET J 1 217 ? 58.728 38.057 16.299 1.00 132.15 ? 217 MET J CA 1 +ATOM 18725 C C . MET J 1 217 ? 60.170 38.189 15.836 1.00 112.39 ? 217 MET J C 1 +ATOM 18726 O O . MET J 1 217 ? 60.878 37.185 15.696 1.00 94.84 ? 217 MET J O 1 +ATOM 18727 C CB . MET J 1 217 ? 57.777 38.366 15.144 1.00 152.05 ? 217 MET J CB 1 +ATOM 18728 C CG . MET J 1 217 ? 57.219 37.116 14.469 1.00 147.00 ? 217 MET J CG 1 +ATOM 18729 S SD . MET J 1 217 ? 58.477 36.210 13.553 1.00 137.65 ? 217 MET J SD 1 +ATOM 18730 C CE . MET J 1 217 ? 57.622 34.691 13.131 1.00 179.77 ? 217 MET J CE 1 +ATOM 18731 N N . SER J 1 218 ? 60.626 39.431 15.719 1.00 102.07 ? 218 SER J N 1 +ATOM 18732 C CA . SER J 1 218 ? 62.018 39.718 15.382 1.00 139.69 ? 218 SER J CA 1 +ATOM 18733 C C . SER J 1 218 ? 63.024 39.022 16.330 1.00 153.87 ? 218 SER J C 1 +ATOM 18734 O O . SER J 1 218 ? 63.963 38.349 15.886 1.00 130.62 ? 218 SER J O 1 +ATOM 18735 C CB . SER J 1 218 ? 62.262 41.233 15.400 1.00 130.29 ? 218 SER J CB 1 +ATOM 18736 O OG . SER J 1 218 ? 63.523 41.558 14.831 1.00 136.05 ? 218 SER J OG 1 +ATOM 18737 N N . ALA J 1 219 ? 62.823 39.204 17.631 1.00 120.26 ? 219 ALA J N 1 +ATOM 18738 C CA . ALA J 1 219 ? 63.753 38.693 18.615 1.00 93.91 ? 219 ALA J CA 1 +ATOM 18739 C C . ALA J 1 219 ? 63.799 37.152 18.583 1.00 106.56 ? 219 ALA J C 1 +ATOM 18740 O O . ALA J 1 219 ? 64.845 36.528 18.821 1.00 94.54 ? 219 ALA J O 1 +ATOM 18741 C CB . ALA J 1 219 ? 63.356 39.209 19.985 1.00 87.61 ? 219 ALA J CB 1 +ATOM 18742 N N . ILE J 1 220 ? 62.656 36.523 18.319 1.00 111.80 ? 220 ILE J N 1 +ATOM 18743 C CA . ILE J 1 220 ? 62.602 35.058 18.260 1.00 115.87 ? 220 ILE J CA 1 +ATOM 18744 C C . ILE J 1 220 ? 63.413 34.550 17.064 1.00 117.74 ? 220 ILE J C 1 +ATOM 18745 O O . ILE J 1 220 ? 64.123 33.545 17.164 1.00 80.91 ? 220 ILE J O 1 +ATOM 18746 C CB . ILE J 1 220 ? 61.144 34.542 18.200 1.00 132.09 ? 220 ILE J CB 1 +ATOM 18747 C CG1 . ILE J 1 220 ? 60.447 34.802 19.549 1.00 110.37 ? 220 ILE J CG1 1 +ATOM 18748 C CG2 . ILE J 1 220 ? 61.107 33.048 17.825 1.00 109.68 ? 220 ILE J CG2 1 +ATOM 18749 C CD1 . ILE J 1 220 ? 58.940 34.715 19.493 1.00 114.23 ? 220 ILE J CD1 1 +ATOM 18750 N N . GLU J 1 221 ? 63.302 35.252 15.933 1.00 114.26 ? 221 GLU J N 1 +ATOM 18751 C CA . GLU J 1 221 ? 64.066 34.899 14.731 1.00 100.85 ? 221 GLU J CA 1 +ATOM 18752 C C . GLU J 1 221 ? 65.554 34.941 15.051 1.00 113.71 ? 221 GLU J C 1 +ATOM 18753 O O . GLU J 1 221 ? 66.296 33.974 14.789 1.00 83.22 ? 221 GLU J O 1 +ATOM 18754 C CB . GLU J 1 221 ? 63.731 35.862 13.590 1.00 78.77 ? 221 GLU J CB 1 +ATOM 18755 C CG . GLU J 1 221 ? 62.368 35.607 12.960 1.00 82.13 ? 221 GLU J CG 1 +ATOM 18756 C CD . GLU J 1 221 ? 61.808 36.784 12.164 1.00 78.52 ? 221 GLU J CD 1 +ATOM 18757 O OE1 . GLU J 1 221 ? 62.076 37.968 12.499 1.00 52.99 ? 221 GLU J OE1 1 +ATOM 18758 O OE2 . GLU J 1 221 ? 61.189 36.501 11.107 1.00 98.45 ? 221 GLU J OE2 1 +ATOM 18759 N N . THR J 1 222 ? 65.971 36.065 15.637 1.00 121.41 ? 222 THR J N 1 +ATOM 18760 C CA . THR J 1 222 ? 67.359 36.280 16.056 1.00 116.56 ? 222 THR J CA 1 +ATOM 18761 C C . THR J 1 222 ? 67.853 35.125 16.922 1.00 107.91 ? 222 THR J C 1 +ATOM 18762 O O . THR J 1 222 ? 68.947 34.593 16.709 1.00 80.51 ? 222 THR J O 1 +ATOM 18763 C CB . THR J 1 222 ? 67.468 37.591 16.857 1.00 110.43 ? 222 THR J CB 1 +ATOM 18764 O OG1 . THR J 1 222 ? 67.307 38.720 15.985 1.00 96.64 ? 222 THR J OG1 1 +ATOM 18765 C CG2 . THR J 1 222 ? 68.817 37.665 17.612 1.00 123.05 ? 222 THR J CG2 1 +ATOM 18766 N N . GLY J 1 223 ? 67.034 34.757 17.904 1.00 112.82 ? 223 GLY J N 1 +ATOM 18767 C CA . GLY J 1 223 ? 67.333 33.626 18.775 1.00 126.01 ? 223 GLY J CA 1 +ATOM 18768 C C . GLY J 1 223 ? 67.550 32.336 17.995 1.00 123.85 ? 223 GLY J C 1 +ATOM 18769 O O . GLY J 1 223 ? 68.437 31.536 18.333 1.00 80.53 ? 223 GLY J O 1 +ATOM 18770 N N . VAL J 1 224 ? 66.730 32.116 16.965 1.00 114.91 ? 224 VAL J N 1 +ATOM 18771 C CA . VAL J 1 224 ? 66.823 30.887 16.186 1.00 120.97 ? 224 VAL J CA 1 +ATOM 18772 C C . VAL J 1 224 ? 68.160 30.855 15.470 1.00 134.46 ? 224 VAL J C 1 +ATOM 18773 O O . VAL J 1 224 ? 68.827 29.819 15.422 1.00 136.96 ? 224 VAL J O 1 +ATOM 18774 C CB . VAL J 1 224 ? 65.692 30.767 15.161 1.00 114.49 ? 224 VAL J CB 1 +ATOM 18775 C CG1 . VAL J 1 224 ? 65.944 29.581 14.238 1.00 106.38 ? 224 VAL J CG1 1 +ATOM 18776 C CG2 . VAL J 1 224 ? 64.351 30.623 15.867 1.00 126.07 ? 224 VAL J CG2 1 +ATOM 18777 N N . ILE J 1 225 ? 68.577 32.006 14.953 1.00 134.10 ? 225 ILE J N 1 +ATOM 18778 C CA . ILE J 1 225 ? 69.871 32.088 14.278 1.00 129.41 ? 225 ILE J CA 1 +ATOM 18779 C C . ILE J 1 225 ? 70.996 31.737 15.247 1.00 114.96 ? 225 ILE J C 1 +ATOM 18780 O O . ILE J 1 225 ? 71.824 30.882 14.930 1.00 80.49 ? 225 ILE J O 1 +ATOM 18781 C CB . ILE J 1 225 ? 70.119 33.480 13.655 1.00 127.49 ? 225 ILE J CB 1 +ATOM 18782 C CG1 . ILE J 1 225 ? 69.161 33.714 12.488 1.00 127.85 ? 225 ILE J CG1 1 +ATOM 18783 C CG2 . ILE J 1 225 ? 71.550 33.591 13.144 1.00 123.19 ? 225 ILE J CG2 1 +ATOM 18784 C CD1 . ILE J 1 225 ? 69.021 35.170 12.093 1.00 130.31 ? 225 ILE J CD1 1 +ATOM 18785 N N . PHE J 1 226 ? 71.017 32.396 16.413 1.00 91.81 ? 226 PHE J N 1 +ATOM 18786 C CA . PHE J 1 226 ? 72.053 32.149 17.417 1.00 99.06 ? 226 PHE J CA 1 +ATOM 18787 C C . PHE J 1 226 ? 72.086 30.673 17.817 1.00 116.36 ? 226 PHE J C 1 +ATOM 18788 O O . PHE J 1 226 ? 73.144 30.125 18.128 1.00 110.60 ? 226 PHE J O 1 +ATOM 18789 C CB . PHE J 1 226 ? 71.845 33.019 18.662 1.00 96.26 ? 226 PHE J CB 1 +ATOM 18790 C CG . PHE J 1 226 ? 72.348 34.438 18.526 1.00 97.12 ? 226 PHE J CG 1 +ATOM 18791 C CD1 . PHE J 1 226 ? 73.705 34.695 18.329 1.00 99.69 ? 226 PHE J CD1 1 +ATOM 18792 C CD2 . PHE J 1 226 ? 71.486 35.525 18.722 1.00 96.07 ? 226 PHE J CD2 1 +ATOM 18793 C CE1 . PHE J 1 226 ? 74.175 36.003 18.224 1.00 98.10 ? 226 PHE J CE1 1 +ATOM 18794 C CE2 . PHE J 1 226 ? 71.955 36.828 18.658 1.00 99.15 ? 226 PHE J CE2 1 +ATOM 18795 C CZ . PHE J 1 226 ? 73.297 37.068 18.378 1.00 109.02 ? 226 PHE J CZ 1 +ATOM 18796 N N . LEU J 1 227 ? 70.922 30.036 17.820 1.00 129.01 ? 227 LEU J N 1 +ATOM 18797 C CA . LEU J 1 227 ? 70.832 28.610 18.133 1.00 133.99 ? 227 LEU J CA 1 +ATOM 18798 C C . LEU J 1 227 ? 71.474 27.750 17.059 1.00 116.80 ? 227 LEU J C 1 +ATOM 18799 O O . LEU J 1 227 ? 72.218 26.832 17.370 1.00 82.55 ? 227 LEU J O 1 +ATOM 18800 C CB . LEU J 1 227 ? 69.366 28.223 18.306 1.00 136.97 ? 227 LEU J CB 1 +ATOM 18801 C CG . LEU J 1 227 ? 68.708 28.612 19.641 1.00 125.78 ? 227 LEU J CG 1 +ATOM 18802 C CD1 . LEU J 1 227 ? 67.204 28.481 19.676 1.00 124.81 ? 227 LEU J CD1 1 +ATOM 18803 C CD2 . LEU J 1 227 ? 69.299 27.834 20.797 1.00 125.03 ? 227 LEU J CD2 1 +ATOM 18804 N N . ILE J 1 228 ? 71.213 28.083 15.798 1.00 132.87 ? 228 ILE J N 1 +ATOM 18805 C CA . ILE J 1 228 ? 71.774 27.331 14.681 1.00 130.66 ? 228 ILE J CA 1 +ATOM 18806 C C . ILE J 1 228 ? 73.282 27.497 14.666 1.00 127.84 ? 228 ILE J C 1 +ATOM 18807 O O . ILE J 1 228 ? 74.021 26.511 14.553 1.00 119.18 ? 228 ILE J O 1 +ATOM 18808 C CB . ILE J 1 228 ? 71.216 27.782 13.311 1.00 129.21 ? 228 ILE J CB 1 +ATOM 18809 C CG1 . ILE J 1 228 ? 69.711 27.512 13.224 1.00 126.96 ? 228 ILE J CG1 1 +ATOM 18810 C CG2 . ILE J 1 228 ? 71.910 27.027 12.186 1.00 113.99 ? 228 ILE J CG2 1 +ATOM 18811 C CD1 . ILE J 1 228 ? 69.009 28.236 12.097 1.00 106.34 ? 228 ILE J CD1 1 +ATOM 18812 N N . ASN J 1 229 ? 73.737 28.742 14.794 1.00 121.84 ? 229 ASN J N 1 +ATOM 18813 C CA . ASN J 1 229 ? 75.170 29.043 14.785 1.00 140.79 ? 229 ASN J CA 1 +ATOM 18814 C C . ASN J 1 229 ? 75.894 28.333 15.935 1.00 138.84 ? 229 ASN J C 1 +ATOM 18815 O O . ASN J 1 229 ? 76.936 27.697 15.736 1.00 78.65 ? 229 ASN J O 1 +ATOM 18816 C CB . ASN J 1 229 ? 75.386 30.557 14.874 1.00 135.66 ? 229 ASN J CB 1 +ATOM 18817 C CG . ASN J 1 229 ? 76.784 30.980 14.460 1.00 176.12 ? 229 ASN J CG 1 +ATOM 18818 O OD1 . ASN J 1 229 ? 77.484 30.259 13.740 1.00 224.24 ? 229 ASN J OD1 1 +ATOM 18819 N ND2 . ASN J 1 229 ? 77.206 32.146 14.935 1.00 172.34 ? 229 ASN J ND2 1 +ATOM 18820 N N . ASP J 1 230 ? 75.278 28.374 17.113 1.00 148.57 ? 230 ASP J N 1 +ATOM 18821 C CA . ASP J 1 230 ? 75.806 27.690 18.279 1.00 156.24 ? 230 ASP J CA 1 +ATOM 18822 C C . ASP J 1 230 ? 75.899 26.181 18.028 1.00 179.03 ? 230 ASP J C 1 +ATOM 18823 O O . ASP J 1 230 ? 76.871 25.529 18.412 1.00 175.28 ? 230 ASP J O 1 +ATOM 18824 C CB . ASP J 1 230 ? 74.925 27.976 19.494 1.00 148.58 ? 230 ASP J CB 1 +ATOM 18825 C CG . ASP J 1 230 ? 75.510 27.422 20.775 1.00 194.70 ? 230 ASP J CG 1 +ATOM 18826 O OD1 . ASP J 1 230 ? 76.515 27.984 21.250 1.00 238.54 ? 230 ASP J OD1 1 +ATOM 18827 O OD2 . ASP J 1 230 ? 74.994 26.414 21.305 1.00 239.85 ? 230 ASP J OD2 1 +ATOM 18828 N N . GLY J 1 231 ? 74.866 25.622 17.407 1.00 194.03 ? 231 GLY J N 1 +ATOM 18829 C CA . GLY J 1 231 ? 74.832 24.191 17.122 1.00 198.36 ? 231 GLY J CA 1 +ATOM 18830 C C . GLY J 1 231 ? 75.882 23.784 16.102 1.00 183.37 ? 231 GLY J C 1 +ATOM 18831 O O . GLY J 1 231 ? 76.453 22.686 16.177 1.00 141.33 ? 231 GLY J O 1 +ATOM 18832 N N . ILE J 1 232 ? 76.132 24.673 15.145 1.00 178.94 ? 232 ILE J N 1 +ATOM 18833 C CA . ILE J 1 232 ? 77.186 24.456 14.165 1.00 168.36 ? 232 ILE J CA 1 +ATOM 18834 C C . ILE J 1 232 ? 78.513 24.344 14.892 1.00 143.78 ? 232 ILE J C 1 +ATOM 18835 O O . ILE J 1 232 ? 79.290 23.409 14.626 1.00 144.34 ? 232 ILE J O 1 +ATOM 18836 C CB . ILE J 1 232 ? 77.234 25.589 13.109 1.00 172.30 ? 232 ILE J CB 1 +ATOM 18837 C CG1 . ILE J 1 232 ? 76.042 25.452 12.154 1.00 172.58 ? 232 ILE J CG1 1 +ATOM 18838 C CG2 . ILE J 1 232 ? 78.549 25.573 12.326 1.00 182.91 ? 232 ILE J CG2 1 +ATOM 18839 C CD1 . ILE J 1 232 ? 75.734 26.707 11.360 1.00 165.66 ? 232 ILE J CD1 1 +ATOM 18840 N N . ASP J 1 233 ? 78.786 25.317 15.765 1.00 106.56 ? 233 ASP J N 1 +ATOM 18841 C CA . ASP J 1 233 ? 80.040 25.349 16.508 1.00 130.90 ? 233 ASP J CA 1 +ATOM 18842 C C . ASP J 1 233 ? 80.201 24.070 17.315 1.00 129.16 ? 233 ASP J C 1 +ATOM 18843 O O . ASP J 1 233 ? 81.271 23.433 17.299 1.00 174.42 ? 233 ASP J O 1 +ATOM 18844 C CB . ASP J 1 233 ? 80.088 26.563 17.446 1.00 143.53 ? 233 ASP J CB 1 +ATOM 18845 C CG . ASP J 1 233 ? 80.124 27.906 16.701 1.00 133.72 ? 233 ASP J CG 1 +ATOM 18846 O OD1 . ASP J 1 233 ? 79.997 27.917 15.465 1.00 96.42 ? 233 ASP J OD1 1 +ATOM 18847 O OD2 . ASP J 1 233 ? 80.388 28.940 17.366 1.00 141.18 ? 233 ASP J OD2 1 +ATOM 18848 N N . ARG J 1 234 ? 79.144 23.689 18.014 1.00 122.65 ? 234 ARG J N 1 +ATOM 18849 C CA . ARG J 1 234 ? 79.219 22.568 18.953 1.00 166.13 ? 234 ARG J CA 1 +ATOM 18850 C C . ARG J 1 234 ? 79.053 21.181 18.311 1.00 152.34 ? 234 ARG J C 1 +ATOM 18851 O O . ARG J 1 234 ? 79.142 20.157 19.007 1.00 125.47 ? 234 ARG J O 1 +ATOM 18852 C CB . ARG J 1 234 ? 78.182 22.750 20.058 1.00 171.70 ? 234 ARG J CB 1 +ATOM 18853 C CG . ARG J 1 234 ? 78.562 23.845 21.026 1.00 169.33 ? 234 ARG J CG 1 +ATOM 18854 C CD . ARG J 1 234 ? 77.360 24.380 21.777 1.00 154.79 ? 234 ARG J CD 1 +ATOM 18855 N NE . ARG J 1 234 ? 77.777 25.475 22.633 1.00 180.27 ? 234 ARG J NE 1 +ATOM 18856 C CZ . ARG J 1 234 ? 77.635 25.487 23.953 1.00 172.63 ? 234 ARG J CZ 1 +ATOM 18857 N NH1 . ARG J 1 234 ? 76.962 24.513 24.568 1.00 113.65 ? 234 ARG J NH1 1 +ATOM 18858 N NH2 . ARG J 1 234 ? 78.133 26.513 24.656 1.00 214.42 ? 234 ARG J NH2 1 +ATOM 18859 N N . GLY J 1 235 ? 78.848 21.149 16.998 1.00 117.70 ? 235 GLY J N 1 +ATOM 18860 C CA . GLY J 1 235 ? 78.807 19.894 16.276 1.00 113.34 ? 235 GLY J CA 1 +ATOM 18861 C C . GLY J 1 235 ? 77.500 19.164 16.471 1.00 115.37 ? 235 GLY J C 1 +ATOM 18862 O O . GLY J 1 235 ? 77.463 17.928 16.458 1.00 98.82 ? 235 GLY J O 1 +ATOM 18863 N N . LEU J 1 236 ? 76.410 19.915 16.631 1.00 141.27 ? 236 LEU J N 1 +ATOM 18864 C CA . LEU J 1 236 ? 75.060 19.307 16.582 1.00 142.32 ? 236 LEU J CA 1 +ATOM 18865 C C . LEU J 1 236 ? 74.722 18.981 15.133 1.00 140.03 ? 236 LEU J C 1 +ATOM 18866 O O . LEU J 1 236 ? 74.292 17.871 14.822 1.00 119.54 ? 236 LEU J O 1 +ATOM 18867 C CB . LEU J 1 236 ? 73.976 20.231 17.164 1.00 117.31 ? 236 LEU J CB 1 +ATOM 18868 C CG . LEU J 1 236 ? 73.772 20.230 18.676 1.00 90.25 ? 236 LEU J CG 1 +ATOM 18869 C CD1 . LEU J 1 236 ? 74.858 21.063 19.364 1.00 109.10 ? 236 LEU J CD1 1 +ATOM 18870 C CD2 . LEU J 1 236 ? 72.405 20.785 19.022 1.00 81.96 ? 236 LEU J CD2 1 +ATOM 18871 N N . TRP J 1 237 ? 74.949 19.951 14.252 1.00 134.04 ? 237 TRP J N 1 +ATOM 18872 C CA . TRP J 1 237 ? 74.635 19.797 12.839 1.00 144.86 ? 237 TRP J CA 1 +ATOM 18873 C C . TRP J 1 237 ? 75.729 20.425 11.975 1.00 178.45 ? 237 TRP J C 1 +ATOM 18874 O O . TRP J 1 237 ? 76.559 21.190 12.477 1.00 193.09 ? 237 TRP J O 1 +ATOM 18875 C CB . TRP J 1 237 ? 73.270 20.416 12.535 1.00 121.50 ? 237 TRP J CB 1 +ATOM 18876 C CG . TRP J 1 237 ? 72.972 21.600 13.374 1.00 117.92 ? 237 TRP J CG 1 +ATOM 18877 C CD1 . TRP J 1 237 ? 73.599 22.805 13.328 1.00 143.00 ? 237 TRP J CD1 1 +ATOM 18878 C CD2 . TRP J 1 237 ? 71.977 21.705 14.402 1.00 140.01 ? 237 TRP J CD2 1 +ATOM 18879 N NE1 . TRP J 1 237 ? 73.055 23.661 14.257 1.00 165.35 ? 237 TRP J NE1 1 +ATOM 18880 C CE2 . TRP J 1 237 ? 72.039 23.020 14.912 1.00 157.17 ? 237 TRP J CE2 1 +ATOM 18881 C CE3 . TRP J 1 237 ? 71.033 20.826 14.931 1.00 148.98 ? 237 TRP J CE3 1 +ATOM 18882 C CZ2 . TRP J 1 237 ? 71.187 23.478 15.926 1.00 141.22 ? 237 TRP J CZ2 1 +ATOM 18883 C CZ3 . TRP J 1 237 ? 70.202 21.280 15.956 1.00 142.34 ? 237 TRP J CZ3 1 +ATOM 18884 C CH2 . TRP J 1 237 ? 70.291 22.590 16.440 1.00 130.32 ? 237 TRP J CH2 1 +ATOM 18885 N N . ASP J 1 238 ? 75.734 20.086 10.684 1.00 191.72 ? 238 ASP J N 1 +ATOM 18886 C CA . ASP J 1 238 ? 76.823 20.477 9.781 1.00 169.76 ? 238 ASP J CA 1 +ATOM 18887 C C . ASP J 1 238 ? 76.329 21.147 8.503 1.00 171.47 ? 238 ASP J C 1 +ATOM 18888 O O . ASP J 1 238 ? 75.255 20.811 7.980 1.00 162.51 ? 238 ASP J O 1 +ATOM 18889 C CB . ASP J 1 238 ? 77.688 19.271 9.415 1.00 123.32 ? 238 ASP J CB 1 +ATOM 18890 C CG . ASP J 1 238 ? 78.252 18.566 10.630 1.00 127.51 ? 238 ASP J CG 1 +ATOM 18891 O OD1 . ASP J 1 238 ? 77.507 17.795 11.259 1.00 123.82 ? 238 ASP J OD1 1 +ATOM 18892 O OD2 . ASP J 1 238 ? 79.433 18.794 10.982 1.00 142.86 ? 238 ASP J OD2 1 +ATOM 18893 N N . LEU J 1 239 ? 77.139 22.076 7.996 1.00 147.60 ? 239 LEU J N 1 +ATOM 18894 C CA . LEU J 1 239 ? 76.806 22.807 6.785 1.00 167.13 ? 239 LEU J CA 1 +ATOM 18895 C C . LEU J 1 239 ? 77.017 21.924 5.562 1.00 189.73 ? 239 LEU J C 1 +ATOM 18896 O O . LEU J 1 239 ? 77.953 21.116 5.517 1.00 187.24 ? 239 LEU J O 1 +ATOM 18897 C CB . LEU J 1 239 ? 77.663 24.075 6.663 1.00 164.27 ? 239 LEU J CB 1 +ATOM 18898 C CG . LEU J 1 239 ? 77.322 25.298 7.511 1.00 153.65 ? 239 LEU J CG 1 +ATOM 18899 C CD1 . LEU J 1 239 ? 78.223 26.471 7.160 1.00 164.87 ? 239 LEU J CD1 1 +ATOM 18900 C CD2 . LEU J 1 239 ? 75.873 25.695 7.326 1.00 135.90 ? 239 LEU J CD2 1 +ATOM 18901 N N . GLN J 1 240 ? 76.151 22.101 4.567 1.00 183.01 ? 240 GLN J N 1 +ATOM 18902 C CA . GLN J 1 240 ? 76.368 21.516 3.248 1.00 176.59 ? 240 GLN J CA 1 +ATOM 18903 C C . GLN J 1 240 ? 77.753 21.882 2.710 1.00 195.53 ? 240 GLN J C 1 +ATOM 18904 O O . GLN J 1 240 ? 78.577 21.008 2.407 1.00 148.21 ? 240 GLN J O 1 +ATOM 18905 C CB . GLN J 1 240 ? 75.282 21.992 2.267 1.00 157.00 ? 240 GLN J CB 1 +ATOM 18906 C CG . GLN J 1 240 ? 75.302 21.265 0.927 1.00 149.77 ? 240 GLN J CG 1 +ATOM 18907 C CD . GLN J 1 240 ? 74.973 19.786 1.070 1.00 159.17 ? 240 GLN J CD 1 +ATOM 18908 O OE1 . GLN J 1 240 ? 73.803 19.408 1.187 1.00 175.37 ? 240 GLN J OE1 1 +ATOM 18909 N NE2 . GLN J 1 240 ? 76.007 18.943 1.115 1.00 144.51 ? 240 GLN J NE2 1 +ATOM 18910 N N . ASN J 1 241 ? 78.001 23.183 2.622 1.00 211.52 ? 241 ASN J N 1 +ATOM 18911 C CA . ASN J 1 241 ? 79.274 23.707 2.174 1.00 184.38 ? 241 ASN J CA 1 +ATOM 18912 C C . ASN J 1 241 ? 80.095 24.223 3.338 1.00 162.87 ? 241 ASN J C 1 +ATOM 18913 O O . ASN J 1 241 ? 79.792 25.289 3.895 1.00 134.60 ? 241 ASN J O 1 +ATOM 18914 C CB . ASN J 1 241 ? 79.042 24.836 1.182 1.00 182.81 ? 241 ASN J CB 1 +ATOM 18915 C CG . ASN J 1 241 ? 79.210 24.373 -0.242 1.00 235.78 ? 241 ASN J CG 1 +ATOM 18916 O OD1 . ASN J 1 241 ? 80.223 24.680 -0.880 1.00 500.00 ? 241 ASN J OD1 1 +ATOM 18917 N ND2 . ASN J 1 241 ? 78.207 23.675 -0.772 1.00 293.05 ? 241 ASN J ND2 1 +ATOM 18918 N N . LYS J 1 242 ? 81.188 23.521 3.637 1.00 133.00 ? 242 LYS J N 1 +ATOM 18919 C CA . LYS J 1 242 ? 82.091 23.944 4.709 1.00 119.31 ? 242 LYS J CA 1 +ATOM 18920 C C . LYS J 1 242 ? 82.742 25.288 4.377 1.00 128.82 ? 242 LYS J C 1 +ATOM 18921 O O . LYS J 1 242 ? 83.092 26.068 5.263 1.00 90.46 ? 242 LYS J O 1 +ATOM 18922 C CB . LYS J 1 242 ? 83.153 22.873 4.967 1.00 111.18 ? 242 LYS J CB 1 +ATOM 18923 C CG . LYS J 1 242 ? 82.582 21.468 5.093 1.00 125.30 ? 242 LYS J CG 1 +ATOM 18924 C CD . LYS J 1 242 ? 83.003 20.799 6.395 1.00 126.04 ? 242 LYS J CD 1 +ATOM 18925 C CE . LYS J 1 242 ? 81.808 20.141 7.076 1.00 146.76 ? 242 LYS J CE 1 +ATOM 18926 N NZ . LYS J 1 242 ? 82.198 19.341 8.266 1.00 138.23 ? 242 LYS J NZ 1 +ATOM 18927 N N . ALA J 1 243 ? 82.858 25.552 3.075 1.00 197.71 ? 243 ALA J N 1 +ATOM 18928 C CA . ALA J 1 243 ? 83.318 26.837 2.547 1.00 215.84 ? 243 ALA J CA 1 +ATOM 18929 C C . ALA J 1 243 ? 82.405 27.987 2.961 1.00 182.84 ? 243 ALA J C 1 +ATOM 18930 O O . ALA J 1 243 ? 82.809 29.152 2.876 1.00 201.73 ? 243 ALA J O 1 +ATOM 18931 C CB . ALA J 1 243 ? 83.419 26.772 1.023 1.00 239.70 ? 243 ALA J CB 1 +ATOM 18932 N N . GLU J 1 244 ? 81.166 27.672 3.340 1.00 142.90 ? 244 GLU J N 1 +ATOM 18933 C CA . GLU J 1 244 ? 80.210 28.718 3.672 1.00 167.43 ? 244 GLU J CA 1 +ATOM 18934 C C . GLU J 1 244 ? 80.228 29.048 5.156 1.00 173.18 ? 244 GLU J C 1 +ATOM 18935 O O . GLU J 1 244 ? 79.336 29.732 5.633 1.00 123.83 ? 244 GLU J O 1 +ATOM 18936 C CB . GLU J 1 244 ? 78.798 28.334 3.224 1.00 181.51 ? 244 GLU J CB 1 +ATOM 18937 C CG . GLU J 1 244 ? 78.579 28.418 1.722 1.00 176.88 ? 244 GLU J CG 1 +ATOM 18938 C CD . GLU J 1 244 ? 77.114 28.295 1.336 1.00 181.59 ? 244 GLU J CD 1 +ATOM 18939 O OE1 . GLU J 1 244 ? 76.584 27.158 1.344 1.00 172.57 ? 244 GLU J OE1 1 +ATOM 18940 O OE2 . GLU J 1 244 ? 76.499 29.335 1.006 1.00 150.52 ? 244 GLU J OE2 1 +ATOM 18941 N N . ARG J 1 245 ? 81.214 28.528 5.888 1.00 182.44 ? 245 ARG J N 1 +ATOM 18942 C CA . ARG J 1 245 ? 81.366 28.867 7.304 1.00 171.05 ? 245 ARG J CA 1 +ATOM 18943 C C . ARG J 1 245 ? 81.501 30.372 7.527 1.00 167.68 ? 245 ARG J C 1 +ATOM 18944 O O . ARG J 1 245 ? 81.020 30.891 8.529 1.00 169.37 ? 245 ARG J O 1 +ATOM 18945 C CB . ARG J 1 245 ? 82.568 28.169 7.929 1.00 154.76 ? 245 ARG J CB 1 +ATOM 18946 C CG . ARG J 1 245 ? 82.659 28.358 9.443 1.00 161.63 ? 245 ARG J CG 1 +ATOM 18947 C CD . ARG J 1 245 ? 83.813 27.569 10.082 1.00 174.96 ? 245 ARG J CD 1 +ATOM 18948 N NE . ARG J 1 245 ? 83.348 26.304 10.652 1.00 183.43 ? 245 ARG J NE 1 +ATOM 18949 C CZ . ARG J 1 245 ? 82.603 26.197 11.752 1.00 189.12 ? 245 ARG J CZ 1 +ATOM 18950 N NH1 . ARG J 1 245 ? 82.216 27.273 12.411 1.00 173.32 ? 245 ARG J NH1 1 +ATOM 18951 N NH2 . ARG J 1 245 ? 82.226 25.001 12.194 1.00 208.25 ? 245 ARG J NH2 1 +ATOM 18952 N N . GLN J 1 246 ? 82.184 31.063 6.617 1.00 173.05 ? 246 GLN J N 1 +ATOM 18953 C CA . GLN J 1 246 ? 82.449 32.498 6.792 1.00 151.37 ? 246 GLN J CA 1 +ATOM 18954 C C . GLN J 1 246 ? 81.369 33.346 6.134 1.00 133.45 ? 246 GLN J C 1 +ATOM 18955 O O . GLN J 1 246 ? 81.607 34.502 5.782 1.00 140.82 ? 246 GLN J O 1 +ATOM 18956 C CB . GLN J 1 246 ? 83.842 32.876 6.257 1.00 154.24 ? 246 GLN J CB 1 +ATOM 18957 C CG . GLN J 1 246 ? 84.999 32.369 7.103 1.00 169.73 ? 246 GLN J CG 1 +ATOM 18958 C CD . GLN J 1 246 ? 85.246 30.883 6.917 1.00 183.52 ? 246 GLN J CD 1 +ATOM 18959 O OE1 . GLN J 1 246 ? 85.267 30.385 5.788 1.00 159.64 ? 246 GLN J OE1 1 +ATOM 18960 N NE2 . GLN J 1 246 ? 85.463 30.172 8.021 1.00 180.84 ? 246 GLN J NE2 1 +ATOM 18961 N N . ASN J 1 247 ? 80.208 32.736 5.903 1.00 101.49 ? 247 ASN J N 1 +ATOM 18962 C CA . ASN J 1 247 ? 79.016 33.459 5.463 1.00 116.13 ? 247 ASN J CA 1 +ATOM 18963 C C . ASN J 1 247 ? 78.896 34.791 6.216 1.00 99.25 ? 247 ASN J C 1 +ATOM 18964 O O . ASN J 1 247 ? 79.068 34.823 7.441 1.00 147.29 ? 247 ASN J O 1 +ATOM 18965 C CB . ASN J 1 247 ? 77.783 32.569 5.725 1.00 137.61 ? 247 ASN J CB 1 +ATOM 18966 C CG . ASN J 1 247 ? 76.610 32.882 4.826 1.00 150.58 ? 247 ASN J CG 1 +ATOM 18967 O OD1 . ASN J 1 247 ? 75.614 33.479 5.264 1.00 142.82 ? 247 ASN J OD1 1 +ATOM 18968 N ND2 . ASN J 1 247 ? 76.734 32.515 3.555 1.00 142.73 ? 247 ASN J ND2 1 +ATOM 18969 N N . ASP J 1 248 ? 78.504 35.852 5.509 1.00 114.09 ? 248 ASP J N 1 +ATOM 18970 C CA . ASP J 1 248 ? 78.320 37.189 6.118 1.00 157.48 ? 248 ASP J CA 1 +ATOM 18971 C C . ASP J 1 248 ? 77.429 37.164 7.372 1.00 191.10 ? 248 ASP J C 1 +ATOM 18972 O O . ASP J 1 248 ? 77.767 37.737 8.418 1.00 204.75 ? 248 ASP J O 1 +ATOM 18973 C CB . ASP J 1 248 ? 77.685 38.168 5.117 1.00 156.02 ? 248 ASP J CB 1 +ATOM 18974 C CG . ASP J 1 248 ? 78.619 38.546 3.991 1.00 170.56 ? 248 ASP J CG 1 +ATOM 18975 O OD1 . ASP J 1 248 ? 79.834 38.708 4.237 1.00 214.32 ? 248 ASP J OD1 1 +ATOM 18976 O OD2 . ASP J 1 248 ? 78.134 38.690 2.854 1.00 160.03 ? 248 ASP J OD2 1 +ATOM 18977 N N . ILE J 1 249 ? 76.287 36.492 7.250 1.00 189.06 ? 249 ILE J N 1 +ATOM 18978 C CA . ILE J 1 249 ? 75.309 36.417 8.325 1.00 150.70 ? 249 ILE J CA 1 +ATOM 18979 C C . ILE J 1 249 ? 75.874 35.633 9.517 1.00 143.17 ? 249 ILE J C 1 +ATOM 18980 O O . ILE J 1 249 ? 75.858 36.106 10.661 1.00 173.14 ? 249 ILE J O 1 +ATOM 18981 C CB . ILE J 1 249 ? 74.012 35.752 7.826 1.00 135.20 ? 249 ILE J CB 1 +ATOM 18982 C CG1 . ILE J 1 249 ? 73.375 36.592 6.716 1.00 132.35 ? 249 ILE J CG1 1 +ATOM 18983 C CG2 . ILE J 1 249 ? 73.026 35.599 8.969 1.00 164.92 ? 249 ILE J CG2 1 +ATOM 18984 C CD1 . ILE J 1 249 ? 72.401 35.830 5.843 1.00 140.38 ? 249 ILE J CD1 1 +ATOM 18985 N N . LEU J 1 250 ? 76.399 34.442 9.236 1.00 115.91 ? 250 LEU J N 1 +ATOM 18986 C CA . LEU J 1 250 ? 76.979 33.592 10.278 1.00 124.15 ? 250 LEU J CA 1 +ATOM 18987 C C . LEU J 1 250 ? 78.113 34.258 11.072 1.00 144.31 ? 250 LEU J C 1 +ATOM 18988 O O . LEU J 1 250 ? 78.210 34.070 12.287 1.00 184.82 ? 250 LEU J O 1 +ATOM 18989 C CB . LEU J 1 250 ? 77.481 32.275 9.683 1.00 125.43 ? 250 LEU J CB 1 +ATOM 18990 C CG . LEU J 1 250 ? 76.395 31.239 9.388 1.00 139.07 ? 250 LEU J CG 1 +ATOM 18991 C CD1 . LEU J 1 250 ? 76.921 30.096 8.535 1.00 167.36 ? 250 LEU J CD1 1 +ATOM 18992 C CD2 . LEU J 1 250 ? 75.825 30.697 10.681 1.00 151.30 ? 250 LEU J CD2 1 +ATOM 18993 N N . VAL J 1 251 ? 78.969 35.018 10.387 1.00 164.09 ? 251 VAL J N 1 +ATOM 18994 C CA . VAL J 1 251 ? 80.070 35.725 11.056 1.00 152.35 ? 251 VAL J CA 1 +ATOM 18995 C C . VAL J 1 251 ? 79.572 36.977 11.781 1.00 177.31 ? 251 VAL J C 1 +ATOM 18996 O O . VAL J 1 251 ? 80.189 37.420 12.756 1.00 249.75 ? 251 VAL J O 1 +ATOM 18997 C CB . VAL J 1 251 ? 81.196 36.122 10.086 1.00 138.77 ? 251 VAL J CB 1 +ATOM 18998 C CG1 . VAL J 1 251 ? 81.702 34.899 9.334 1.00 129.73 ? 251 VAL J CG1 1 +ATOM 18999 C CG2 . VAL J 1 251 ? 80.737 37.219 9.123 1.00 148.85 ? 251 VAL J CG2 1 +ATOM 19000 N N . LYS J 1 252 ? 78.447 37.529 11.325 1.00 141.64 ? 252 LYS J N 1 +ATOM 19001 C CA . LYS J 1 252 ? 77.808 38.648 12.013 1.00 129.27 ? 252 LYS J CA 1 +ATOM 19002 C C . LYS J 1 252 ? 77.278 38.220 13.402 1.00 161.29 ? 252 LYS J C 1 +ATOM 19003 O O . LYS J 1 252 ? 77.544 38.883 14.418 1.00 151.66 ? 252 LYS J O 1 +ATOM 19004 C CB . LYS J 1 252 ? 76.687 39.198 11.137 1.00 112.40 ? 252 LYS J CB 1 +ATOM 19005 C CG . LYS J 1 252 ? 75.917 40.361 11.732 1.00 118.08 ? 252 LYS J CG 1 +ATOM 19006 C CD . LYS J 1 252 ? 74.809 40.797 10.780 1.00 130.53 ? 252 LYS J CD 1 +ATOM 19007 C CE . LYS J 1 252 ? 73.476 40.981 11.497 1.00 137.66 ? 252 LYS J CE 1 +ATOM 19008 N NZ . LYS J 1 252 ? 72.330 41.154 10.558 1.00 138.30 ? 252 LYS J NZ 1 +ATOM 19009 N N . TYR J 1 253 ? 76.591 37.075 13.448 1.00 169.97 ? 253 TYR J N 1 +ATOM 19010 C CA . TYR J 1 253 ? 76.027 36.541 14.702 1.00 127.12 ? 253 TYR J CA 1 +ATOM 19011 C C . TYR J 1 253 ? 77.097 35.888 15.565 1.00 126.71 ? 253 TYR J C 1 +ATOM 19012 O O . TYR J 1 253 ? 77.037 35.946 16.796 1.00 172.00 ? 253 TYR J O 1 +ATOM 19013 C CB . TYR J 1 253 ? 74.893 35.550 14.411 1.00 92.33 ? 253 TYR J CB 1 +ATOM 19014 C CG . TYR J 1 253 ? 73.652 36.254 13.903 1.00 117.13 ? 253 TYR J CG 1 +ATOM 19015 C CD1 . TYR J 1 253 ? 72.754 36.862 14.784 1.00 142.98 ? 253 TYR J CD1 1 +ATOM 19016 C CD2 . TYR J 1 253 ? 73.425 36.416 12.544 1.00 133.11 ? 253 TYR J CD2 1 +ATOM 19017 C CE1 . TYR J 1 253 ? 71.634 37.538 14.315 1.00 141.37 ? 253 TYR J CE1 1 +ATOM 19018 C CE2 . TYR J 1 253 ? 72.317 37.117 12.071 1.00 133.85 ? 253 TYR J CE2 1 +ATOM 19019 C CZ . TYR J 1 253 ? 71.418 37.657 12.965 1.00 129.60 ? 253 TYR J CZ 1 +ATOM 19020 O OH . TYR J 1 253 ? 70.306 38.332 12.504 1.00 131.62 ? 253 TYR J OH 1 +ATOM 19021 N N . ARG J 1 254 ? 78.089 35.289 14.917 1.00 116.28 ? 254 ARG J N 1 +ATOM 19022 C CA . ARG J 1 254 ? 79.300 34.850 15.609 1.00 124.44 ? 254 ARG J CA 1 +ATOM 19023 C C . ARG J 1 254 ? 79.950 36.023 16.353 1.00 123.16 ? 254 ARG J C 1 +ATOM 19024 O O . ARG J 1 254 ? 80.455 35.864 17.464 1.00 113.27 ? 254 ARG J O 1 +ATOM 19025 C CB . ARG J 1 254 ? 80.303 34.240 14.615 1.00 140.79 ? 254 ARG J CB 1 +ATOM 19026 C CG . ARG J 1 254 ? 81.523 33.629 15.282 1.00 141.84 ? 254 ARG J CG 1 +ATOM 19027 C CD . ARG J 1 254 ? 82.270 32.681 14.367 1.00 159.80 ? 254 ARG J CD 1 +ATOM 19028 N NE . ARG J 1 254 ? 81.497 31.486 14.018 1.00 166.58 ? 254 ARG J NE 1 +ATOM 19029 C CZ . ARG J 1 254 ? 80.977 31.228 12.818 1.00 160.63 ? 254 ARG J CZ 1 +ATOM 19030 N NH1 . ARG J 1 254 ? 81.112 32.089 11.816 1.00 171.94 ? 254 ARG J NH1 1 +ATOM 19031 N NH2 . ARG J 1 254 ? 80.318 30.090 12.615 1.00 127.62 ? 254 ARG J NH2 1 +ATOM 19032 N N . HIS J 1 255 ? 79.969 37.189 15.708 1.00 129.90 ? 255 HIS J N 1 +ATOM 19033 C CA . HIS J 1 255 ? 80.596 38.385 16.272 1.00 150.31 ? 255 HIS J CA 1 +ATOM 19034 C C . HIS J 1 255 ? 79.817 38.929 17.452 1.00 137.10 ? 255 HIS J C 1 +ATOM 19035 O O . HIS J 1 255 ? 80.412 39.462 18.390 1.00 172.93 ? 255 HIS J O 1 +ATOM 19036 C CB . HIS J 1 255 ? 80.776 39.481 15.198 1.00 175.29 ? 255 HIS J CB 1 +ATOM 19037 C CG . HIS J 1 255 ? 82.198 39.666 14.761 1.00 172.68 ? 255 HIS J CG 1 +ATOM 19038 N ND1 . HIS J 1 255 ? 82.850 38.763 13.947 1.00 173.04 ? 255 HIS J ND1 1 +ATOM 19039 C CD2 . HIS J 1 255 ? 83.102 40.632 15.052 1.00 159.28 ? 255 HIS J CD2 1 +ATOM 19040 C CE1 . HIS J 1 255 ? 84.091 39.171 13.749 1.00 173.73 ? 255 HIS J CE1 1 +ATOM 19041 N NE2 . HIS J 1 255 ? 84.270 40.301 14.411 1.00 174.53 ? 255 HIS J NE2 1 +ATOM 19042 N N . MET J 1 256 ? 78.496 38.818 17.401 1.00 111.94 ? 256 MET J N 1 +ATOM 19043 C CA . MET J 1 256 ? 77.685 39.303 18.510 1.00 122.04 ? 256 MET J CA 1 +ATOM 19044 C C . MET J 1 256 ? 77.923 38.464 19.777 1.00 145.21 ? 256 MET J C 1 +ATOM 19045 O O . MET J 1 256 ? 77.720 38.952 20.904 1.00 152.75 ? 256 MET J O 1 +ATOM 19046 C CB . MET J 1 256 ? 76.209 39.340 18.118 1.00 136.53 ? 256 MET J CB 1 +ATOM 19047 C CG . MET J 1 256 ? 75.937 40.125 16.837 1.00 154.39 ? 256 MET J CG 1 +ATOM 19048 S SD . MET J 1 256 ? 74.231 40.670 16.591 1.00 158.65 ? 256 MET J SD 1 +ATOM 19049 C CE . MET J 1 256 ? 74.103 41.921 17.887 1.00 105.20 ? 256 MET J CE 1 +ATOM 19050 N N . SER J 1 257 ? 78.404 37.229 19.592 1.00 160.33 ? 257 SER J N 1 +ATOM 19051 C CA . SER J 1 257 ? 78.826 36.356 20.699 1.00 139.61 ? 257 SER J CA 1 +ATOM 19052 C C . SER J 1 257 ? 80.221 36.765 21.185 1.00 127.66 ? 257 SER J C 1 +ATOM 19053 O O . SER J 1 257 ? 80.328 37.598 22.090 1.00 135.43 ? 257 SER J O 1 +ATOM 19054 C CB . SER J 1 257 ? 78.823 34.878 20.268 1.00 114.07 ? 257 SER J CB 1 +ATOM 19055 O OG . SER J 1 257 ? 77.674 34.577 19.464 1.00 112.44 ? 257 SER J OG 1 +ATOM 19056 N N . LEU K 1 2 ? 50.256 56.072 5.027 1.00 155.14 ? 2 LEU K N 1 +ATOM 19057 C CA . LEU K 1 2 ? 50.444 55.917 6.506 1.00 147.52 ? 2 LEU K CA 1 +ATOM 19058 C C . LEU K 1 2 ? 49.180 55.320 7.150 1.00 141.03 ? 2 LEU K C 1 +ATOM 19059 O O . LEU K 1 2 ? 48.423 56.006 7.886 1.00 78.80 ? 2 LEU K O 1 +ATOM 19060 C CB . LEU K 1 2 ? 50.829 57.254 7.162 1.00 144.62 ? 2 LEU K CB 1 +ATOM 19061 C CG . LEU K 1 2 ? 52.144 57.938 6.732 1.00 143.74 ? 2 LEU K CG 1 +ATOM 19062 C CD1 . LEU K 1 2 ? 52.305 59.243 7.500 1.00 141.30 ? 2 LEU K CD1 1 +ATOM 19063 C CD2 . LEU K 1 2 ? 53.401 57.077 6.893 1.00 157.15 ? 2 LEU K CD2 1 +ATOM 19064 N N . THR K 1 3 ? 48.897 54.082 6.729 1.00 180.81 ? 3 THR K N 1 +ATOM 19065 C CA . THR K 1 3 ? 47.966 53.176 7.408 1.00 202.52 ? 3 THR K CA 1 +ATOM 19066 C C . THR K 1 3 ? 48.497 51.745 7.361 1.00 180.65 ? 3 THR K C 1 +ATOM 19067 O O . THR K 1 3 ? 47.941 50.846 8.003 1.00 190.70 ? 3 THR K O 1 +ATOM 19068 C CB . THR K 1 3 ? 46.559 53.151 6.779 1.00 210.88 ? 3 THR K CB 1 +ATOM 19069 O OG1 . THR K 1 3 ? 46.619 52.527 5.489 1.00 227.20 ? 3 THR K OG1 1 +ATOM 19070 C CG2 . THR K 1 3 ? 45.974 54.560 6.688 1.00 226.51 ? 3 THR K CG2 1 +ATOM 19071 N N . ALA K 1 4 ? 49.586 51.523 6.626 1.00 162.04 ? 4 ALA K N 1 +ATOM 19072 C CA . ALA K 1 4 ? 50.340 50.283 6.796 1.00 164.48 ? 4 ALA K CA 1 +ATOM 19073 C C . ALA K 1 4 ? 51.271 50.392 8.035 1.00 166.05 ? 4 ALA K C 1 +ATOM 19074 O O . ALA K 1 4 ? 51.166 51.381 8.773 1.00 148.02 ? 4 ALA K O 1 +ATOM 19075 C CB . ALA K 1 4 ? 51.126 49.955 5.542 1.00 127.20 ? 4 ALA K CB 1 +ATOM 19076 N N . PRO K 1 5 ? 52.106 49.356 8.321 1.00 151.22 ? 5 PRO K N 1 +ATOM 19077 C CA . PRO K 1 5 ? 52.693 49.413 9.651 1.00 121.83 ? 5 PRO K CA 1 +ATOM 19078 C C . PRO K 1 5 ? 54.033 50.143 9.696 1.00 139.23 ? 5 PRO K C 1 +ATOM 19079 O O . PRO K 1 5 ? 54.605 50.470 8.654 1.00 136.49 ? 5 PRO K O 1 +ATOM 19080 C CB . PRO K 1 5 ? 52.904 47.943 9.998 1.00 122.63 ? 5 PRO K CB 1 +ATOM 19081 C CG . PRO K 1 5 ? 53.092 47.237 8.690 1.00 128.24 ? 5 PRO K CG 1 +ATOM 19082 C CD . PRO K 1 5 ? 52.482 48.108 7.616 1.00 148.42 ? 5 PRO K CD 1 +ATOM 19083 N N . PRO K 1 6 ? 54.502 50.459 10.908 1.00 137.54 ? 6 PRO K N 1 +ATOM 19084 C CA . PRO K 1 6 ? 55.883 50.903 11.088 1.00 130.84 ? 6 PRO K CA 1 +ATOM 19085 C C . PRO K 1 6 ? 56.871 49.733 11.129 1.00 119.04 ? 6 PRO K C 1 +ATOM 19086 O O . PRO K 1 6 ? 56.526 48.635 11.540 1.00 105.93 ? 6 PRO K O 1 +ATOM 19087 C CB . PRO K 1 6 ? 55.857 51.646 12.422 1.00 113.55 ? 6 PRO K CB 1 +ATOM 19088 C CG . PRO K 1 6 ? 54.613 51.219 13.114 1.00 103.35 ? 6 PRO K CG 1 +ATOM 19089 C CD . PRO K 1 6 ? 53.679 50.606 12.120 1.00 113.26 ? 6 PRO K CD 1 +ATOM 19090 N N . LYS K 1 7 ? 58.088 49.968 10.668 1.00 125.82 ? 7 LYS K N 1 +ATOM 19091 C CA . LYS K 1 7 ? 59.114 48.920 10.636 1.00 134.92 ? 7 LYS K CA 1 +ATOM 19092 C C . LYS K 1 7 ? 60.029 49.007 11.845 1.00 134.08 ? 7 LYS K C 1 +ATOM 19093 O O . LYS K 1 7 ? 60.001 49.990 12.591 1.00 105.02 ? 7 LYS K O 1 +ATOM 19094 C CB . LYS K 1 7 ? 59.928 48.972 9.329 1.00 127.17 ? 7 LYS K CB 1 +ATOM 19095 C CG . LYS K 1 7 ? 59.153 48.560 8.096 1.00 115.93 ? 7 LYS K CG 1 +ATOM 19096 C CD . LYS K 1 7 ? 58.712 49.737 7.241 1.00 114.93 ? 7 LYS K CD 1 +ATOM 19097 C CE . LYS K 1 7 ? 58.192 49.255 5.903 1.00 136.63 ? 7 LYS K CE 1 +ATOM 19098 N NZ . LYS K 1 7 ? 57.156 50.164 5.337 1.00 149.24 ? 7 LYS K NZ 1 +ATOM 19099 N N . GLU K 1 8 ? 60.856 47.981 12.016 1.00 178.61 ? 8 GLU K N 1 +ATOM 19100 C CA . GLU K 1 8 ? 61.613 47.793 13.251 1.00 205.82 ? 8 GLU K CA 1 +ATOM 19101 C C . GLU K 1 8 ? 62.716 48.847 13.496 1.00 195.25 ? 8 GLU K C 1 +ATOM 19102 O O . GLU K 1 8 ? 63.620 49.016 12.701 1.00 176.07 ? 8 GLU K O 1 +ATOM 19103 C CB . GLU K 1 8 ? 62.133 46.365 13.336 1.00 209.11 ? 8 GLU K CB 1 +ATOM 19104 C CG . GLU K 1 8 ? 61.280 45.513 14.324 1.00 211.51 ? 8 GLU K CG 1 +ATOM 19105 C CD . GLU K 1 8 ? 60.348 44.500 13.650 1.00 177.45 ? 8 GLU K CD 1 +ATOM 19106 O OE1 . GLU K 1 8 ? 59.713 44.896 12.649 1.00 140.01 ? 8 GLU K OE1 1 +ATOM 19107 O OE2 . GLU K 1 8 ? 60.194 43.346 14.160 1.00 147.63 ? 8 GLU K OE2 1 +ATOM 19108 N N . ALA K 1 9 ? 62.557 49.623 14.565 1.00 187.02 ? 9 ALA K N 1 +ATOM 19109 C CA . ALA K 1 9 ? 63.531 50.637 14.973 1.00 141.33 ? 9 ALA K CA 1 +ATOM 19110 C C . ALA K 1 9 ? 64.442 50.074 16.062 1.00 107.66 ? 9 ALA K C 1 +ATOM 19111 O O . ALA K 1 9 ? 63.989 49.774 17.166 1.00 109.87 ? 9 ALA K O 1 +ATOM 19112 C CB . ALA K 1 9 ? 62.802 51.862 15.491 1.00 140.56 ? 9 ALA K CB 1 +ATOM 19113 N N . ALA K 1 10 ? 65.719 49.937 15.734 1.00 91.83 ? 10 ALA K N 1 +ATOM 19114 C CA . ALA K 1 10 ? 66.727 49.270 16.576 1.00 84.47 ? 10 ALA K CA 1 +ATOM 19115 C C . ALA K 1 10 ? 66.700 47.770 16.355 1.00 81.08 ? 10 ALA K C 1 +ATOM 19116 O O . ALA K 1 10 ? 65.727 47.211 15.877 1.00 88.04 ? 10 ALA K O 1 +ATOM 19117 C CB . ALA K 1 10 ? 66.582 49.615 18.052 1.00 79.52 ? 10 ALA K CB 1 +ATOM 19118 N N . ARG K 1 11 ? 67.830 47.134 16.620 1.00 103.52 ? 11 ARG K N 1 +ATOM 19119 C CA . ARG K 1 11 ? 68.086 45.759 16.162 1.00 139.60 ? 11 ARG K CA 1 +ATOM 19120 C C . ARG K 1 11 ? 67.906 44.776 17.316 1.00 125.21 ? 11 ARG K C 1 +ATOM 19121 O O . ARG K 1 11 ? 68.171 45.128 18.472 1.00 160.66 ? 11 ARG K O 1 +ATOM 19122 C CB . ARG K 1 11 ? 69.535 45.658 15.660 1.00 172.31 ? 11 ARG K CB 1 +ATOM 19123 C CG . ARG K 1 11 ? 70.499 45.844 16.851 1.00 205.44 ? 11 ARG K CG 1 +ATOM 19124 C CD . ARG K 1 11 ? 71.589 46.860 16.631 1.00 206.40 ? 11 ARG K CD 1 +ATOM 19125 N NE . ARG K 1 11 ? 71.737 47.747 17.805 1.00 217.15 ? 11 ARG K NE 1 +ATOM 19126 C CZ . ARG K 1 11 ? 71.002 48.820 18.169 1.00 181.61 ? 11 ARG K CZ 1 +ATOM 19127 N NH1 . ARG K 1 11 ? 70.010 49.297 17.420 1.00 184.42 ? 11 ARG K NH1 1 +ATOM 19128 N NH2 . ARG K 1 11 ? 71.273 49.437 19.322 1.00 127.54 ? 11 ARG K NH2 1 +ATOM 19129 N N . PRO K 1 12 ? 67.542 43.526 17.007 1.00 101.10 ? 12 PRO K N 1 +ATOM 19130 C CA . PRO K 1 12 ? 67.727 42.515 18.016 1.00 115.89 ? 12 PRO K CA 1 +ATOM 19131 C C . PRO K 1 12 ? 69.208 42.316 18.379 1.00 112.27 ? 12 PRO K C 1 +ATOM 19132 O O . PRO K 1 12 ? 69.998 41.866 17.553 1.00 87.98 ? 12 PRO K O 1 +ATOM 19133 C CB . PRO K 1 12 ? 67.142 41.242 17.359 1.00 117.04 ? 12 PRO K CB 1 +ATOM 19134 C CG . PRO K 1 12 ? 66.434 41.696 16.134 1.00 98.95 ? 12 PRO K CG 1 +ATOM 19135 C CD . PRO K 1 12 ? 67.135 42.945 15.722 1.00 102.57 ? 12 PRO K CD 1 +ATOM 19136 N N . THR K 1 13 ? 69.558 42.652 19.618 1.00 125.00 ? 13 THR K N 1 +ATOM 19137 C CA . THR K 1 13 ? 70.813 42.216 20.215 1.00 140.04 ? 13 THR K CA 1 +ATOM 19138 C C . THR K 1 13 ? 70.618 40.971 21.100 1.00 130.40 ? 13 THR K C 1 +ATOM 19139 O O . THR K 1 13 ? 69.499 40.684 21.519 1.00 180.49 ? 13 THR K O 1 +ATOM 19140 C CB . THR K 1 13 ? 71.385 43.336 21.082 1.00 145.31 ? 13 THR K CB 1 +ATOM 19141 O OG1 . THR K 1 13 ? 72.729 43.001 21.451 1.00 182.82 ? 13 THR K OG1 1 +ATOM 19142 C CG2 . THR K 1 13 ? 70.504 43.590 22.350 1.00 125.18 ? 13 THR K CG2 1 +ATOM 19143 N N . LEU K 1 14 ? 71.680 40.230 21.401 1.00 105.45 ? 14 LEU K N 1 +ATOM 19144 C CA . LEU K 1 14 ? 71.538 39.196 22.441 1.00 112.90 ? 14 LEU K CA 1 +ATOM 19145 C C . LEU K 1 14 ? 71.537 39.886 23.803 1.00 105.74 ? 14 LEU K C 1 +ATOM 19146 O O . LEU K 1 14 ? 71.885 41.046 23.879 1.00 94.27 ? 14 LEU K O 1 +ATOM 19147 C CB . LEU K 1 14 ? 72.571 38.078 22.337 1.00 104.15 ? 14 LEU K CB 1 +ATOM 19148 C CG . LEU K 1 14 ? 74.028 38.455 22.276 1.00 128.13 ? 14 LEU K CG 1 +ATOM 19149 C CD1 . LEU K 1 14 ? 74.878 37.396 22.953 1.00 140.74 ? 14 LEU K CD1 1 +ATOM 19150 C CD2 . LEU K 1 14 ? 74.434 38.588 20.825 1.00 161.77 ? 14 LEU K CD2 1 +ATOM 19151 N N . MET K 1 15 ? 71.003 39.248 24.840 1.00 125.83 ? 15 MET K N 1 +ATOM 19152 C CA . MET K 1 15 ? 70.462 40.005 25.984 1.00 127.48 ? 15 MET K CA 1 +ATOM 19153 C C . MET K 1 15 ? 71.591 40.658 26.778 1.00 110.54 ? 15 MET K C 1 +ATOM 19154 O O . MET K 1 15 ? 72.521 39.975 27.214 1.00 75.53 ? 15 MET K O 1 +ATOM 19155 C CB . MET K 1 15 ? 69.605 39.126 26.920 1.00 146.46 ? 15 MET K CB 1 +ATOM 19156 C CG . MET K 1 15 ? 68.522 39.909 27.671 1.00 124.22 ? 15 MET K CG 1 +ATOM 19157 S SD . MET K 1 15 ? 68.017 39.417 29.328 1.00 128.23 ? 15 MET K SD 1 +ATOM 19158 C CE . MET K 1 15 ? 69.424 38.496 29.995 1.00 157.37 ? 15 MET K CE 1 +ATOM 19159 N N . PRO K 1 16 ? 71.505 41.992 26.970 1.00 107.18 ? 16 PRO K N 1 +ATOM 19160 C CA . PRO K 1 16 ? 72.588 42.821 27.524 1.00 90.81 ? 16 PRO K CA 1 +ATOM 19161 C C . PRO K 1 16 ? 72.940 42.516 28.983 1.00 93.89 ? 16 PRO K C 1 +ATOM 19162 O O . PRO K 1 16 ? 72.524 43.228 29.892 1.00 74.13 ? 16 PRO K O 1 +ATOM 19163 C CB . PRO K 1 16 ? 72.046 44.252 27.375 1.00 88.89 ? 16 PRO K CB 1 +ATOM 19164 C CG . PRO K 1 16 ? 70.568 44.091 27.324 1.00 103.72 ? 16 PRO K CG 1 +ATOM 19165 C CD . PRO K 1 16 ? 70.345 42.815 26.574 1.00 104.66 ? 16 PRO K CD 1 +ATOM 19166 N N . ARG K 1 17 ? 73.762 41.489 29.182 1.00 113.47 ? 17 ARG K N 1 +ATOM 19167 C CA . ARG K 1 17 ? 74.310 41.161 30.503 1.00 124.61 ? 17 ARG K CA 1 +ATOM 19168 C C . ARG K 1 17 ? 75.627 41.894 30.704 1.00 115.12 ? 17 ARG K C 1 +ATOM 19169 O O . ARG K 1 17 ? 76.341 42.142 29.741 1.00 97.37 ? 17 ARG K O 1 +ATOM 19170 C CB . ARG K 1 17 ? 74.541 39.654 30.613 1.00 148.55 ? 17 ARG K CB 1 +ATOM 19171 C CG . ARG K 1 17 ? 73.314 38.882 31.069 1.00 144.56 ? 17 ARG K CG 1 +ATOM 19172 C CD . ARG K 1 17 ? 73.408 37.391 30.778 1.00 136.43 ? 17 ARG K CD 1 +ATOM 19173 N NE . ARG K 1 17 ? 73.113 37.082 29.378 1.00 141.18 ? 17 ARG K NE 1 +ATOM 19174 C CZ . ARG K 1 17 ? 73.282 35.885 28.831 1.00 141.56 ? 17 ARG K CZ 1 +ATOM 19175 N NH1 . ARG K 1 17 ? 73.714 34.880 29.587 1.00 138.85 ? 17 ARG K NH1 1 +ATOM 19176 N NH2 . ARG K 1 17 ? 72.994 35.683 27.550 1.00 117.32 ? 17 ARG K NH2 1 +ATOM 19177 N N . ALA K 1 18 ? 75.911 42.309 31.933 1.00 129.24 ? 18 ALA K N 1 +ATOM 19178 C CA . ALA K 1 18 ? 77.092 43.146 32.196 1.00 134.41 ? 18 ALA K CA 1 +ATOM 19179 C C . ALA K 1 18 ? 78.130 42.419 33.065 1.00 126.00 ? 18 ALA K C 1 +ATOM 19180 O O . ALA K 1 18 ? 78.676 41.401 32.647 1.00 86.86 ? 18 ALA K O 1 +ATOM 19181 C CB . ALA K 1 18 ? 76.702 44.499 32.804 1.00 108.90 ? 18 ALA K CB 1 +ATOM 19182 N N . GLN K 1 19 ? 78.435 42.979 34.236 1.00 108.37 ? 19 GLN K N 1 +ATOM 19183 C CA . GLN K 1 19 ? 79.669 42.646 34.930 1.00 94.29 ? 19 GLN K CA 1 +ATOM 19184 C C . GLN K 1 19 ? 79.615 41.212 35.440 1.00 89.22 ? 19 GLN K C 1 +ATOM 19185 O O . GLN K 1 19 ? 80.589 40.439 35.307 1.00 111.00 ? 19 GLN K O 1 +ATOM 19186 C CB . GLN K 1 19 ? 79.921 43.635 36.077 1.00 93.60 ? 19 GLN K CB 1 +ATOM 19187 C CG . GLN K 1 19 ? 81.263 43.466 36.786 1.00 112.85 ? 19 GLN K CG 1 +ATOM 19188 C CD . GLN K 1 19 ? 82.445 43.509 35.830 1.00 136.38 ? 19 GLN K CD 1 +ATOM 19189 O OE1 . GLN K 1 19 ? 82.726 44.539 35.215 1.00 130.12 ? 19 GLN K OE1 1 +ATOM 19190 N NE2 . GLN K 1 19 ? 83.127 42.376 35.680 1.00 155.85 ? 19 GLN K NE2 1 +ATOM 19191 N N . SER K 1 20 ? 78.522 40.910 36.132 1.00 72.20 ? 20 SER K N 1 +ATOM 19192 C CA . SER K 1 20 ? 78.283 39.596 36.684 1.00 63.26 ? 20 SER K CA 1 +ATOM 19193 C C . SER K 1 20 ? 78.594 38.548 35.633 1.00 70.25 ? 20 SER K C 1 +ATOM 19194 O O . SER K 1 20 ? 79.317 37.560 35.905 1.00 60.14 ? 20 SER K O 1 +ATOM 19195 C CB . SER K 1 20 ? 76.826 39.514 37.130 1.00 54.11 ? 20 SER K CB 1 +ATOM 19196 O OG . SER K 1 20 ? 76.506 40.582 38.018 1.00 44.35 ? 20 SER K OG 1 +ATOM 19197 N N . TYR K 1 21 ? 78.084 38.785 34.428 1.00 80.30 ? 21 TYR K N 1 +ATOM 19198 C CA . TYR K 1 21 ? 78.298 37.864 33.298 1.00 137.75 ? 21 TYR K CA 1 +ATOM 19199 C C . TYR K 1 21 ? 79.792 37.676 32.986 1.00 128.23 ? 21 TYR K C 1 +ATOM 19200 O O . TYR K 1 21 ? 80.280 36.546 32.818 1.00 60.84 ? 21 TYR K O 1 +ATOM 19201 C CB . TYR K 1 21 ? 77.557 38.388 32.053 1.00 149.19 ? 21 TYR K CB 1 +ATOM 19202 C CG . TYR K 1 21 ? 77.679 37.507 30.827 1.00 159.58 ? 21 TYR K CG 1 +ATOM 19203 C CD1 . TYR K 1 21 ? 76.931 36.339 30.704 1.00 164.62 ? 21 TYR K CD1 1 +ATOM 19204 C CD2 . TYR K 1 21 ? 78.550 37.832 29.802 1.00 168.19 ? 21 TYR K CD2 1 +ATOM 19205 C CE1 . TYR K 1 21 ? 77.064 35.515 29.607 1.00 149.75 ? 21 TYR K CE1 1 +ATOM 19206 C CE2 . TYR K 1 21 ? 78.678 37.007 28.695 1.00 168.47 ? 21 TYR K CE2 1 +ATOM 19207 C CZ . TYR K 1 21 ? 77.925 35.853 28.609 1.00 136.51 ? 21 TYR K CZ 1 +ATOM 19208 O OH . TYR K 1 21 ? 78.088 34.981 27.564 1.00 166.54 ? 21 TYR K OH 1 +ATOM 19209 N N . LYS K 1 22 ? 80.500 38.797 32.888 1.00 140.09 ? 22 LYS K N 1 +ATOM 19210 C CA . LYS K 1 22 ? 81.915 38.785 32.521 1.00 134.12 ? 22 LYS K CA 1 +ATOM 19211 C C . LYS K 1 22 ? 82.732 37.983 33.522 1.00 129.94 ? 22 LYS K C 1 +ATOM 19212 O O . LYS K 1 22 ? 83.667 37.274 33.147 1.00 113.82 ? 22 LYS K O 1 +ATOM 19213 C CB . LYS K 1 22 ? 82.450 40.224 32.419 1.00 117.16 ? 22 LYS K CB 1 +ATOM 19214 C CG . LYS K 1 22 ? 82.282 40.865 31.049 1.00 119.53 ? 22 LYS K CG 1 +ATOM 19215 C CD . LYS K 1 22 ? 83.524 40.887 30.189 1.00 121.24 ? 22 LYS K CD 1 +ATOM 19216 C CE . LYS K 1 22 ? 83.083 40.836 28.726 1.00 136.05 ? 22 LYS K CE 1 +ATOM 19217 N NZ . LYS K 1 22 ? 82.582 39.486 28.366 1.00 154.70 ? 22 LYS K NZ 1 +ATOM 19218 N N . ASP K 1 23 ? 82.411 38.162 34.802 1.00 129.28 ? 23 ASP K N 1 +ATOM 19219 C CA . ASP K 1 23 ? 83.061 37.409 35.876 1.00 123.50 ? 23 ASP K CA 1 +ATOM 19220 C C . ASP K 1 23 ? 82.719 35.938 35.749 1.00 105.09 ? 23 ASP K C 1 +ATOM 19221 O O . ASP K 1 23 ? 83.599 35.071 35.862 1.00 106.26 ? 23 ASP K O 1 +ATOM 19222 C CB . ASP K 1 23 ? 82.600 37.917 37.247 1.00 122.32 ? 23 ASP K CB 1 +ATOM 19223 C CG . ASP K 1 23 ? 83.113 39.302 37.562 1.00 119.86 ? 23 ASP K CG 1 +ATOM 19224 O OD1 . ASP K 1 23 ? 84.286 39.568 37.238 1.00 105.48 ? 23 ASP K OD1 1 +ATOM 19225 O OD2 . ASP K 1 23 ? 82.326 40.114 38.100 1.00 91.24 ? 23 ASP K OD2 1 +ATOM 19226 N N . LEU K 1 24 ? 81.439 35.668 35.500 1.00 86.76 ? 24 LEU K N 1 +ATOM 19227 C CA . LEU K 1 24 ? 80.916 34.301 35.479 1.00 99.49 ? 24 LEU K CA 1 +ATOM 19228 C C . LEU K 1 24 ? 81.521 33.474 34.340 1.00 111.13 ? 24 LEU K C 1 +ATOM 19229 O O . LEU K 1 24 ? 81.763 32.250 34.489 1.00 76.19 ? 24 LEU K O 1 +ATOM 19230 C CB . LEU K 1 24 ? 79.392 34.335 35.338 1.00 104.81 ? 24 LEU K CB 1 +ATOM 19231 C CG . LEU K 1 24 ? 78.637 32.994 35.300 1.00 114.17 ? 24 LEU K CG 1 +ATOM 19232 C CD1 . LEU K 1 24 ? 78.336 32.493 36.699 1.00 126.25 ? 24 LEU K CD1 1 +ATOM 19233 C CD2 . LEU K 1 24 ? 77.349 33.141 34.505 1.00 118.99 ? 24 LEU K CD2 1 +ATOM 19234 N N . THR K 1 25 ? 81.761 34.135 33.203 1.00 117.31 ? 25 THR K N 1 +ATOM 19235 C CA . THR K 1 25 ? 82.292 33.452 32.019 1.00 112.34 ? 25 THR K CA 1 +ATOM 19236 C C . THR K 1 25 ? 83.785 33.130 32.161 1.00 104.79 ? 25 THR K C 1 +ATOM 19237 O O . THR K 1 25 ? 84.217 31.997 31.884 1.00 61.68 ? 25 THR K O 1 +ATOM 19238 C CB . THR K 1 25 ? 82.058 34.285 30.744 1.00 100.99 ? 25 THR K CB 1 +ATOM 19239 O OG1 . THR K 1 25 ? 82.434 35.643 30.985 1.00 78.49 ? 25 THR K OG1 1 +ATOM 19240 C CG2 . THR K 1 25 ? 80.600 34.218 30.329 1.00 85.75 ? 25 THR K CG2 1 +ATOM 19241 N N . HIS K 1 26 ? 84.559 34.126 32.602 1.00 125.87 ? 26 HIS K N 1 +ATOM 19242 C CA . HIS K 1 26 ? 86.018 34.000 32.731 1.00 134.72 ? 26 HIS K CA 1 +ATOM 19243 C C . HIS K 1 26 ? 86.421 33.341 34.062 1.00 119.43 ? 26 HIS K C 1 +ATOM 19244 O O . HIS K 1 26 ? 87.416 33.707 34.670 1.00 121.20 ? 26 HIS K O 1 +ATOM 19245 C CB . HIS K 1 26 ? 86.686 35.378 32.559 1.00 130.55 ? 26 HIS K CB 1 +ATOM 19246 C CG . HIS K 1 26 ? 86.503 35.967 31.193 1.00 144.73 ? 26 HIS K CG 1 +ATOM 19247 N ND1 . HIS K 1 26 ? 85.283 36.437 30.750 1.00 162.07 ? 26 HIS K ND1 1 +ATOM 19248 C CD2 . HIS K 1 26 ? 87.364 36.122 30.157 1.00 133.32 ? 26 HIS K CD2 1 +ATOM 19249 C CE1 . HIS K 1 26 ? 85.406 36.860 29.504 1.00 152.41 ? 26 HIS K CE1 1 +ATOM 19250 N NE2 . HIS K 1 26 ? 86.660 36.693 29.124 1.00 135.73 ? 26 HIS K NE2 1 +ATOM 19251 N N . LEU K 1 27 ? 85.631 32.375 34.516 1.00 114.12 ? 27 LEU K N 1 +ATOM 19252 C CA . LEU K 1 27 ? 85.971 31.624 35.716 1.00 105.23 ? 27 LEU K CA 1 +ATOM 19253 C C . LEU K 1 27 ? 86.836 30.443 35.328 1.00 95.68 ? 27 LEU K C 1 +ATOM 19254 O O . LEU K 1 27 ? 86.515 29.725 34.372 1.00 109.91 ? 27 LEU K O 1 +ATOM 19255 C CB . LEU K 1 27 ? 84.702 31.139 36.442 1.00 108.63 ? 27 LEU K CB 1 +ATOM 19256 C CG . LEU K 1 27 ? 84.116 32.127 37.457 1.00 119.70 ? 27 LEU K CG 1 +ATOM 19257 C CD1 . LEU K 1 27 ? 82.721 31.715 37.879 1.00 105.96 ? 27 LEU K CD1 1 +ATOM 19258 C CD2 . LEU K 1 27 ? 85.019 32.264 38.679 1.00 128.48 ? 27 LEU K CD2 1 +ATOM 19259 N N . PRO K 1 28 ? 87.925 30.212 36.081 1.00 81.38 ? 28 PRO K N 1 +ATOM 19260 C CA . PRO K 1 28 ? 88.804 29.050 35.835 1.00 90.49 ? 28 PRO K CA 1 +ATOM 19261 C C . PRO K 1 28 ? 88.080 27.711 35.901 1.00 94.68 ? 28 PRO K C 1 +ATOM 19262 O O . PRO K 1 28 ? 87.364 27.451 36.843 1.00 74.35 ? 28 PRO K O 1 +ATOM 19263 C CB . PRO K 1 28 ? 89.822 29.128 36.968 1.00 95.03 ? 28 PRO K CB 1 +ATOM 19264 C CG . PRO K 1 28 ? 89.124 29.887 38.052 1.00 89.59 ? 28 PRO K CG 1 +ATOM 19265 C CD . PRO K 1 28 ? 88.243 30.878 37.351 1.00 77.49 ? 28 PRO K CD 1 +ATOM 19266 N N . ALA K 1 29 ? 88.230 26.891 34.870 1.00 134.58 ? 29 ALA K N 1 +ATOM 19267 C CA . ALA K 1 29 ? 87.373 25.716 34.694 1.00 143.85 ? 29 ALA K CA 1 +ATOM 19268 C C . ALA K 1 29 ? 87.705 24.596 35.709 1.00 116.73 ? 29 ALA K C 1 +ATOM 19269 O O . ALA K 1 29 ? 88.852 24.447 36.137 1.00 71.45 ? 29 ALA K O 1 +ATOM 19270 C CB . ALA K 1 29 ? 87.460 25.203 33.248 1.00 164.47 ? 29 ALA K CB 1 +ATOM 19271 N N . PRO K 1 30 ? 86.688 23.809 36.093 1.00 115.91 ? 30 PRO K N 1 +ATOM 19272 C CA . PRO K 1 30 ? 86.866 22.663 36.987 1.00 110.83 ? 30 PRO K CA 1 +ATOM 19273 C C . PRO K 1 30 ? 87.466 21.462 36.258 1.00 84.70 ? 30 PRO K C 1 +ATOM 19274 O O . PRO K 1 30 ? 87.581 21.490 35.036 1.00 62.74 ? 30 PRO K O 1 +ATOM 19275 C CB . PRO K 1 30 ? 85.432 22.351 37.426 1.00 123.14 ? 30 PRO K CB 1 +ATOM 19276 C CG . PRO K 1 30 ? 84.583 22.789 36.280 1.00 120.64 ? 30 PRO K CG 1 +ATOM 19277 C CD . PRO K 1 30 ? 85.287 23.957 35.649 1.00 118.14 ? 30 PRO K CD 1 +ATOM 19278 N N . THR K 1 31 ? 87.732 20.383 36.994 1.00 93.59 ? 31 THR K N 1 +ATOM 19279 C CA . THR K 1 31 ? 88.284 19.146 36.404 1.00 125.14 ? 31 THR K CA 1 +ATOM 19280 C C . THR K 1 31 ? 87.306 18.431 35.459 1.00 126.30 ? 31 THR K C 1 +ATOM 19281 O O . THR K 1 31 ? 87.722 17.739 34.538 1.00 147.09 ? 31 THR K O 1 +ATOM 19282 C CB . THR K 1 31 ? 88.782 18.131 37.473 1.00 131.92 ? 31 THR K CB 1 +ATOM 19283 O OG1 . THR K 1 31 ? 87.748 17.842 38.419 1.00 136.63 ? 31 THR K OG1 1 +ATOM 19284 C CG2 . THR K 1 31 ? 90.000 18.673 38.212 1.00 142.30 ? 31 THR K CG2 1 +ATOM 19285 N N . GLY K 1 32 ? 86.013 18.601 35.701 1.00 135.45 ? 32 GLY K N 1 +ATOM 19286 C CA . GLY K 1 32 ? 84.979 18.203 34.752 1.00 133.45 ? 32 GLY K CA 1 +ATOM 19287 C C . GLY K 1 32 ? 83.726 19.007 35.037 1.00 142.66 ? 32 GLY K C 1 +ATOM 19288 O O . GLY K 1 32 ? 83.559 19.503 36.155 1.00 160.15 ? 32 GLY K O 1 +ATOM 19289 N N . LYS K 1 33 ? 82.861 19.185 34.039 1.00 133.24 ? 33 LYS K N 1 +ATOM 19290 C CA . LYS K 1 33 ? 81.604 19.899 34.275 1.00 133.75 ? 33 LYS K CA 1 +ATOM 19291 C C . LYS K 1 33 ? 80.666 19.075 35.163 1.00 151.74 ? 33 LYS K C 1 +ATOM 19292 O O . LYS K 1 33 ? 80.770 17.847 35.189 1.00 139.55 ? 33 LYS K O 1 +ATOM 19293 C CB . LYS K 1 33 ? 80.900 20.247 32.973 1.00 112.13 ? 33 LYS K CB 1 +ATOM 19294 C CG . LYS K 1 33 ? 81.289 21.594 32.405 1.00 111.71 ? 33 LYS K CG 1 +ATOM 19295 C CD . LYS K 1 33 ? 80.686 21.797 31.029 1.00 116.03 ? 33 LYS K CD 1 +ATOM 19296 C CE . LYS K 1 33 ? 81.514 22.773 30.206 1.00 118.13 ? 33 LYS K CE 1 +ATOM 19297 N NZ . LYS K 1 33 ? 81.037 22.853 28.801 1.00 112.37 ? 33 LYS K NZ 1 +ATOM 19298 N N . ILE K 1 34 ? 79.823 19.754 35.947 1.00 152.63 ? 34 ILE K N 1 +ATOM 19299 C CA . ILE K 1 34 ? 78.978 19.083 36.928 1.00 136.37 ? 34 ILE K CA 1 +ATOM 19300 C C . ILE K 1 34 ? 77.539 19.132 36.419 1.00 103.28 ? 34 ILE K C 1 +ATOM 19301 O O . ILE K 1 34 ? 77.166 20.053 35.699 1.00 58.80 ? 34 ILE K O 1 +ATOM 19302 C CB . ILE K 1 34 ? 79.136 19.697 38.349 1.00 156.54 ? 34 ILE K CB 1 +ATOM 19303 C CG1 . ILE K 1 34 ? 80.544 19.432 38.904 1.00 156.05 ? 34 ILE K CG1 1 +ATOM 19304 C CG2 . ILE K 1 34 ? 78.144 19.098 39.339 1.00 198.48 ? 34 ILE K CG2 1 +ATOM 19305 C CD1 . ILE K 1 34 ? 81.332 20.694 39.175 1.00 172.69 ? 34 ILE K CD1 1 +ATOM 19306 N N . PHE K 1 35 ? 76.828 18.019 36.621 1.00 113.06 ? 35 PHE K N 1 +ATOM 19307 C CA . PHE K 1 35 ? 75.454 17.826 36.134 1.00 105.03 ? 35 PHE K CA 1 +ATOM 19308 C C . PHE K 1 35 ? 74.496 18.434 37.127 1.00 95.35 ? 35 PHE K C 1 +ATOM 19309 O O . PHE K 1 35 ? 74.514 18.076 38.299 1.00 83.80 ? 35 PHE K O 1 +ATOM 19310 C CB . PHE K 1 35 ? 75.124 16.335 36.050 1.00 105.89 ? 35 PHE K CB 1 +ATOM 19311 C CG . PHE K 1 35 ? 75.469 15.681 34.747 1.00 80.82 ? 35 PHE K CG 1 +ATOM 19312 C CD1 . PHE K 1 35 ? 75.111 16.251 33.542 1.00 61.73 ? 35 PHE K CD1 1 +ATOM 19313 C CD2 . PHE K 1 35 ? 76.054 14.410 34.756 1.00 72.64 ? 35 PHE K CD2 1 +ATOM 19314 C CE1 . PHE K 1 35 ? 75.508 15.650 32.367 1.00 68.56 ? 35 PHE K CE1 1 +ATOM 19315 C CE2 . PHE K 1 35 ? 76.392 13.782 33.582 1.00 66.52 ? 35 PHE K CE2 1 +ATOM 19316 C CZ . PHE K 1 35 ? 76.133 14.409 32.384 1.00 70.59 ? 35 PHE K CZ 1 +ATOM 19317 N N . VAL K 1 36 ? 73.631 19.315 36.651 1.00 88.11 ? 36 VAL K N 1 +ATOM 19318 C CA . VAL K 1 36 ? 72.786 20.047 37.561 1.00 84.42 ? 36 VAL K CA 1 +ATOM 19319 C C . VAL K 1 36 ? 71.331 20.034 37.096 1.00 72.55 ? 36 VAL K C 1 +ATOM 19320 O O . VAL K 1 36 ? 71.052 20.047 35.895 1.00 91.15 ? 36 VAL K O 1 +ATOM 19321 C CB . VAL K 1 36 ? 73.290 21.494 37.752 1.00 79.06 ? 36 VAL K CB 1 +ATOM 19322 C CG1 . VAL K 1 36 ? 72.958 22.349 36.538 1.00 97.96 ? 36 VAL K CG1 1 +ATOM 19323 C CG2 . VAL K 1 36 ? 72.667 22.094 38.990 1.00 86.05 ? 36 VAL K CG2 1 +ATOM 19324 N N . SER K 1 37 ? 70.408 20.080 38.052 1.00 52.12 ? 37 SER K N 1 +ATOM 19325 C CA . SER K 1 37 ? 69.003 20.178 37.744 1.00 44.36 ? 37 SER K CA 1 +ATOM 19326 C C . SER K 1 37 ? 68.433 21.436 38.312 1.00 41.35 ? 37 SER K C 1 +ATOM 19327 O O . SER K 1 37 ? 68.612 21.722 39.488 1.00 47.22 ? 37 SER K O 1 +ATOM 19328 C CB . SER K 1 37 ? 68.304 18.998 38.362 1.00 40.35 ? 37 SER K CB 1 +ATOM 19329 O OG . SER K 1 37 ? 68.570 17.806 37.638 1.00 45.66 ? 37 SER K OG 1 +ATOM 19330 N N . VAL K 1 38 ? 67.661 22.163 37.530 1.00 38.17 ? 38 VAL K N 1 +ATOM 19331 C CA . VAL K 1 38 ? 66.828 23.187 38.135 1.00 52.88 ? 38 VAL K CA 1 +ATOM 19332 C C . VAL K 1 38 ? 65.356 22.878 37.826 1.00 67.85 ? 38 VAL K C 1 +ATOM 19333 O O . VAL K 1 38 ? 64.954 22.939 36.639 1.00 105.11 ? 38 VAL K O 1 +ATOM 19334 C CB . VAL K 1 38 ? 67.181 24.608 37.625 1.00 52.78 ? 38 VAL K CB 1 +ATOM 19335 C CG1 . VAL K 1 38 ? 66.239 25.650 38.224 1.00 55.81 ? 38 VAL K CG1 1 +ATOM 19336 C CG2 . VAL K 1 38 ? 68.629 24.975 37.916 1.00 40.37 ? 38 VAL K CG2 1 +ATOM 19337 N N . TYR K 1 39 ? 64.540 22.685 38.883 1.00 55.14 ? 39 TYR K N 1 +ATOM 19338 C CA . TYR K 1 39 ? 63.097 22.449 38.731 1.00 51.61 ? 39 TYR K CA 1 +ATOM 19339 C C . TYR K 1 39 ? 62.257 23.752 38.717 1.00 71.96 ? 39 TYR K C 1 +ATOM 19340 O O . TYR K 1 39 ? 61.524 24.034 37.755 1.00 75.27 ? 39 TYR K O 1 +ATOM 19341 C CB . TYR K 1 39 ? 62.629 21.526 39.808 1.00 43.37 ? 39 TYR K CB 1 +ATOM 19342 C CG . TYR K 1 39 ? 62.866 20.087 39.444 1.00 44.45 ? 39 TYR K CG 1 +ATOM 19343 C CD1 . TYR K 1 39 ? 64.105 19.514 39.569 1.00 40.44 ? 39 TYR K CD1 1 +ATOM 19344 C CD2 . TYR K 1 39 ? 61.813 19.271 39.021 1.00 53.30 ? 39 TYR K CD2 1 +ATOM 19345 C CE1 . TYR K 1 39 ? 64.307 18.174 39.274 1.00 41.09 ? 39 TYR K CE1 1 +ATOM 19346 C CE2 . TYR K 1 39 ? 62.003 17.912 38.769 1.00 54.62 ? 39 TYR K CE2 1 +ATOM 19347 C CZ . TYR K 1 39 ? 63.267 17.373 38.905 1.00 43.39 ? 39 TYR K CZ 1 +ATOM 19348 O OH . TYR K 1 39 ? 63.456 16.044 38.596 1.00 43.50 ? 39 TYR K OH 1 +ATOM 19349 N N . ASN K 1 40 ? 62.482 24.625 39.690 1.00 84.54 ? 40 ASN K N 1 +ATOM 19350 C CA . ASN K 1 40 ? 61.752 25.888 39.730 1.00 79.77 ? 40 ASN K CA 1 +ATOM 19351 C C . ASN K 1 40 ? 62.316 26.886 40.748 1.00 87.11 ? 40 ASN K C 1 +ATOM 19352 O O . ASN K 1 40 ? 62.557 26.546 41.911 1.00 109.39 ? 40 ASN K O 1 +ATOM 19353 C CB . ASN K 1 40 ? 60.290 25.610 40.056 1.00 81.85 ? 40 ASN K CB 1 +ATOM 19354 C CG . ASN K 1 40 ? 59.394 26.769 39.705 1.00 117.48 ? 40 ASN K CG 1 +ATOM 19355 O OD1 . ASN K 1 40 ? 58.778 27.377 40.583 1.00 139.81 ? 40 ASN K OD1 1 +ATOM 19356 N ND2 . ASN K 1 40 ? 59.339 27.108 38.420 1.00 125.47 ? 40 ASN K ND2 1 +ATOM 19357 N N . ILE K 1 41 ? 62.471 28.134 40.322 1.00 85.36 ? 41 ILE K N 1 +ATOM 19358 C CA . ILE K 1 41 ? 62.721 29.228 41.240 1.00 91.20 ? 41 ILE K CA 1 +ATOM 19359 C C . ILE K 1 41 ? 61.534 30.204 41.220 1.00 90.47 ? 41 ILE K C 1 +ATOM 19360 O O . ILE K 1 41 ? 61.274 30.834 40.194 1.00 117.28 ? 41 ILE K O 1 +ATOM 19361 C CB . ILE K 1 41 ? 64.028 29.967 40.881 1.00 90.70 ? 41 ILE K CB 1 +ATOM 19362 C CG1 . ILE K 1 41 ? 65.252 29.207 41.405 1.00 92.99 ? 41 ILE K CG1 1 +ATOM 19363 C CG2 . ILE K 1 41 ? 64.062 31.339 41.556 1.00 121.85 ? 41 ILE K CG2 1 +ATOM 19364 C CD1 . ILE K 1 41 ? 65.565 27.921 40.692 1.00 79.47 ? 41 ILE K CD1 1 +ATOM 19365 N N . GLN K 1 42 ? 60.855 30.376 42.361 1.00 73.29 ? 42 GLN K N 1 +ATOM 19366 C CA . GLN K 1 42 ? 59.573 31.098 42.396 1.00 75.56 ? 42 GLN K CA 1 +ATOM 19367 C C . GLN K 1 42 ? 59.730 32.579 42.680 1.00 70.52 ? 42 GLN K C 1 +ATOM 19368 O O . GLN K 1 42 ? 60.737 33.011 43.242 1.00 75.84 ? 42 GLN K O 1 +ATOM 19369 C CB . GLN K 1 42 ? 58.642 30.531 43.455 1.00 97.79 ? 42 GLN K CB 1 +ATOM 19370 C CG . GLN K 1 42 ? 58.187 29.108 43.205 1.00 111.19 ? 42 GLN K CG 1 +ATOM 19371 C CD . GLN K 1 42 ? 58.629 28.153 44.312 1.00 145.85 ? 42 GLN K CD 1 +ATOM 19372 O OE1 . GLN K 1 42 ? 57.939 28.003 45.328 1.00 143.85 ? 42 GLN K OE1 1 +ATOM 19373 N NE2 . GLN K 1 42 ? 59.820 27.563 44.160 1.00 129.54 ? 42 GLN K NE2 1 +ATOM 19374 N N . ASP K 1 43 ? 58.726 33.352 42.259 1.00 60.29 ? 43 ASP K N 1 +ATOM 19375 C CA . ASP K 1 43 ? 58.629 34.766 42.602 1.00 55.63 ? 43 ASP K CA 1 +ATOM 19376 C C . ASP K 1 43 ? 58.033 34.917 43.982 1.00 55.89 ? 43 ASP K C 1 +ATOM 19377 O O . ASP K 1 43 ? 56.914 35.380 44.131 1.00 40.98 ? 43 ASP K O 1 +ATOM 19378 C CB . ASP K 1 43 ? 57.746 35.488 41.590 1.00 81.59 ? 43 ASP K CB 1 +ATOM 19379 C CG . ASP K 1 43 ? 57.753 37.014 41.786 1.00 106.56 ? 43 ASP K CG 1 +ATOM 19380 O OD1 . ASP K 1 43 ? 58.854 37.593 41.863 1.00 151.22 ? 43 ASP K OD1 1 +ATOM 19381 O OD2 . ASP K 1 43 ? 56.671 37.654 41.796 1.00 89.90 ? 43 ASP K OD2 1 +ATOM 19382 N N . GLU K 1 44 ? 58.765 34.456 45.002 1.00 89.25 ? 44 GLU K N 1 +ATOM 19383 C CA . GLU K 1 44 ? 58.268 34.425 46.407 1.00 78.70 ? 44 GLU K CA 1 +ATOM 19384 C C . GLU K 1 44 ? 58.095 35.845 46.978 1.00 59.05 ? 44 GLU K C 1 +ATOM 19385 O O . GLU K 1 44 ? 58.003 36.024 48.184 1.00 39.38 ? 44 GLU K O 1 +ATOM 19386 C CB . GLU K 1 44 ? 59.194 33.537 47.297 1.00 67.34 ? 44 GLU K CB 1 +ATOM 19387 C CG . GLU K 1 44 ? 58.830 32.048 47.340 1.00 78.31 ? 44 GLU K CG 1 +ATOM 19388 C CD . GLU K 1 44 ? 59.786 31.179 48.195 1.00 83.71 ? 44 GLU K CD 1 +ATOM 19389 O OE1 . GLU K 1 44 ? 60.153 31.554 49.334 1.00 65.78 ? 44 GLU K OE1 1 +ATOM 19390 O OE2 . GLU K 1 44 ? 60.115 30.053 47.765 1.00 86.08 ? 44 GLU K OE2 1 +ATOM 19391 N N . THR K 1 45 ? 58.143 36.842 46.090 1.00 56.47 ? 45 THR K N 1 +ATOM 19392 C CA . THR K 1 45 ? 58.308 38.225 46.495 1.00 76.44 ? 45 THR K CA 1 +ATOM 19393 C C . THR K 1 45 ? 56.999 38.753 47.066 1.00 73.53 ? 45 THR K C 1 +ATOM 19394 O O . THR K 1 45 ? 57.022 39.564 47.988 1.00 99.18 ? 45 THR K O 1 +ATOM 19395 C CB . THR K 1 45 ? 58.896 39.138 45.357 1.00 90.79 ? 45 THR K CB 1 +ATOM 19396 O OG1 . THR K 1 45 ? 59.272 40.410 45.882 1.00 98.65 ? 45 THR K OG1 1 +ATOM 19397 C CG2 . THR K 1 45 ? 57.893 39.392 44.230 1.00 91.52 ? 45 THR K CG2 1 +ATOM 19398 N N . GLY K 1 46 ? 55.888 38.443 46.414 1.00 71.92 ? 46 GLY K N 1 +ATOM 19399 C CA . GLY K 1 46 ? 54.557 38.888 46.872 1.00 91.21 ? 46 GLY K CA 1 +ATOM 19400 C C . GLY K 1 46 ? 54.065 40.248 46.356 1.00 88.70 ? 46 GLY K C 1 +ATOM 19401 O O . GLY K 1 46 ? 53.210 40.925 46.943 1.00 83.84 ? 46 GLY K O 1 +ATOM 19402 N N . GLN K 1 47 ? 54.650 40.705 45.277 1.00 83.07 ? 47 GLN K N 1 +ATOM 19403 C CA . GLN K 1 47 ? 54.589 42.094 45.023 1.00 79.29 ? 47 GLN K CA 1 +ATOM 19404 C C . GLN K 1 47 ? 54.177 42.385 43.592 1.00 76.07 ? 47 GLN K C 1 +ATOM 19405 O O . GLN K 1 47 ? 54.605 41.707 42.665 1.00 62.67 ? 47 GLN K O 1 +ATOM 19406 C CB . GLN K 1 47 ? 55.924 42.705 45.366 1.00 74.13 ? 47 GLN K CB 1 +ATOM 19407 C CG . GLN K 1 47 ? 56.239 42.718 46.857 1.00 64.84 ? 47 GLN K CG 1 +ATOM 19408 C CD . GLN K 1 47 ? 55.122 43.288 47.711 1.00 73.69 ? 47 GLN K CD 1 +ATOM 19409 O OE1 . GLN K 1 47 ? 54.831 44.479 47.660 1.00 66.27 ? 47 GLN K OE1 1 +ATOM 19410 N NE2 . GLN K 1 47 ? 54.457 42.439 48.465 1.00 87.43 ? 47 GLN K NE2 1 +ATOM 19411 N N . PHE K 1 48 ? 53.322 43.394 43.453 1.00 77.68 ? 48 PHE K N 1 +ATOM 19412 C CA . PHE K 1 48 ? 52.806 43.832 42.166 1.00 81.87 ? 48 PHE K CA 1 +ATOM 19413 C C . PHE K 1 48 ? 53.048 45.318 41.962 1.00 116.66 ? 48 PHE K C 1 +ATOM 19414 O O . PHE K 1 48 ? 53.370 46.056 42.916 1.00 190.55 ? 48 PHE K O 1 +ATOM 19415 C CB . PHE K 1 48 ? 51.290 43.579 42.069 1.00 78.64 ? 48 PHE K CB 1 +ATOM 19416 C CG . PHE K 1 48 ? 50.935 42.147 42.079 1.00 67.31 ? 48 PHE K CG 1 +ATOM 19417 C CD1 . PHE K 1 48 ? 51.016 41.433 43.235 1.00 67.44 ? 48 PHE K CD1 1 +ATOM 19418 C CD2 . PHE K 1 48 ? 50.674 41.496 40.905 1.00 78.49 ? 48 PHE K CD2 1 +ATOM 19419 C CE1 . PHE K 1 48 ? 50.829 40.087 43.240 1.00 80.96 ? 48 PHE K CE1 1 +ATOM 19420 C CE2 . PHE K 1 48 ? 50.458 40.154 40.898 1.00 85.29 ? 48 PHE K CE2 1 +ATOM 19421 C CZ . PHE K 1 48 ? 50.506 39.452 42.074 1.00 88.34 ? 48 PHE K CZ 1 +ATOM 19422 N N . LYS K 1 49 ? 52.831 45.768 40.724 1.00 101.62 ? 49 LYS K N 1 +ATOM 19423 C CA . LYS K 1 49 ? 53.118 47.147 40.341 1.00 76.48 ? 49 LYS K CA 1 +ATOM 19424 C C . LYS K 1 49 ? 51.969 48.019 40.751 1.00 66.22 ? 49 LYS K C 1 +ATOM 19425 O O . LYS K 1 49 ? 50.824 47.558 40.788 1.00 61.06 ? 49 LYS K O 1 +ATOM 19426 C CB . LYS K 1 49 ? 53.384 47.259 38.842 1.00 78.21 ? 49 LYS K CB 1 +ATOM 19427 C CG . LYS K 1 49 ? 54.664 46.539 38.412 1.00 85.67 ? 49 LYS K CG 1 +ATOM 19428 C CD . LYS K 1 49 ? 55.130 46.772 36.985 1.00 96.82 ? 49 LYS K CD 1 +ATOM 19429 C CE . LYS K 1 49 ? 56.505 46.124 36.848 1.00 101.55 ? 49 LYS K CE 1 +ATOM 19430 N NZ . LYS K 1 49 ? 57.171 46.290 35.526 1.00 131.80 ? 49 LYS K NZ 1 +ATOM 19431 N N . PRO K 1 50 ? 52.281 49.262 41.142 1.00 78.78 ? 50 PRO K N 1 +ATOM 19432 C CA . PRO K 1 50 ? 51.268 50.228 41.593 1.00 106.19 ? 50 PRO K CA 1 +ATOM 19433 C C . PRO K 1 50 ? 50.581 50.897 40.424 1.00 122.52 ? 50 PRO K C 1 +ATOM 19434 O O . PRO K 1 50 ? 51.008 50.742 39.261 1.00 167.71 ? 50 PRO K O 1 +ATOM 19435 C CB . PRO K 1 50 ? 52.075 51.269 42.385 1.00 104.71 ? 50 PRO K CB 1 +ATOM 19436 C CG . PRO K 1 50 ? 53.435 51.206 41.778 1.00 125.00 ? 50 PRO K CG 1 +ATOM 19437 C CD . PRO K 1 50 ? 53.649 49.774 41.337 1.00 98.39 ? 50 PRO K CD 1 +ATOM 19438 N N . TYR K 1 51 ? 49.506 51.623 40.717 1.00 125.80 ? 51 TYR K N 1 +ATOM 19439 C CA . TYR K 1 51 ? 48.846 52.423 39.692 1.00 115.08 ? 51 TYR K CA 1 +ATOM 19440 C C . TYR K 1 51 ? 49.886 53.293 38.998 1.00 142.50 ? 51 TYR K C 1 +ATOM 19441 O O . TYR K 1 51 ? 50.754 53.858 39.670 1.00 149.16 ? 51 TYR K O 1 +ATOM 19442 C CB . TYR K 1 51 ? 47.771 53.310 40.301 1.00 84.48 ? 51 TYR K CB 1 +ATOM 19443 C CG . TYR K 1 51 ? 46.889 53.892 39.243 1.00 103.03 ? 51 TYR K CG 1 +ATOM 19444 C CD1 . TYR K 1 51 ? 45.802 53.175 38.769 1.00 131.89 ? 51 TYR K CD1 1 +ATOM 19445 C CD2 . TYR K 1 51 ? 47.134 55.149 38.696 1.00 130.21 ? 51 TYR K CD2 1 +ATOM 19446 C CE1 . TYR K 1 51 ? 44.969 53.691 37.792 1.00 168.42 ? 51 TYR K CE1 1 +ATOM 19447 C CE2 . TYR K 1 51 ? 46.285 55.693 37.723 1.00 168.36 ? 51 TYR K CE2 1 +ATOM 19448 C CZ . TYR K 1 51 ? 45.227 54.931 37.248 1.00 184.88 ? 51 TYR K CZ 1 +ATOM 19449 O OH . TYR K 1 51 ? 44.360 55.393 36.275 1.00 206.10 ? 51 TYR K OH 1 +ATOM 19450 N N . PRO K 1 52 ? 49.830 53.387 37.648 1.00 146.93 ? 52 PRO K N 1 +ATOM 19451 C CA . PRO K 1 52 ? 48.814 52.899 36.715 1.00 124.88 ? 52 PRO K CA 1 +ATOM 19452 C C . PRO K 1 52 ? 49.044 51.541 36.081 1.00 156.95 ? 52 PRO K C 1 +ATOM 19453 O O . PRO K 1 52 ? 48.365 51.232 35.089 1.00 223.46 ? 52 PRO K O 1 +ATOM 19454 C CB . PRO K 1 52 ? 48.860 53.938 35.606 1.00 131.98 ? 52 PRO K CB 1 +ATOM 19455 C CG . PRO K 1 52 ? 50.307 54.308 35.537 1.00 153.09 ? 52 PRO K CG 1 +ATOM 19456 C CD . PRO K 1 52 ? 50.817 54.242 36.958 1.00 167.55 ? 52 PRO K CD 1 +ATOM 19457 N N . ALA K 1 53 ? 49.920 50.710 36.651 1.00 139.21 ? 53 ALA K N 1 +ATOM 19458 C CA . ALA K 1 53 ? 50.069 49.350 36.136 1.00 125.10 ? 53 ALA K CA 1 +ATOM 19459 C C . ALA K 1 53 ? 48.765 48.530 36.265 1.00 119.45 ? 53 ALA K C 1 +ATOM 19460 O O . ALA K 1 53 ? 47.862 48.865 37.072 1.00 63.26 ? 53 ALA K O 1 +ATOM 19461 C CB . ALA K 1 53 ? 51.196 48.629 36.833 1.00 114.16 ? 53 ALA K CB 1 +ATOM 19462 N N . SER K 1 54 ? 48.665 47.468 35.457 1.00 117.05 ? 54 SER K N 1 +ATOM 19463 C CA . SER K 1 54 ? 47.615 46.488 35.672 1.00 95.77 ? 54 SER K CA 1 +ATOM 19464 C C . SER K 1 54 ? 47.748 45.924 37.079 1.00 114.64 ? 54 SER K C 1 +ATOM 19465 O O . SER K 1 54 ? 48.850 45.744 37.622 1.00 130.38 ? 54 SER K O 1 +ATOM 19466 C CB . SER K 1 54 ? 47.654 45.353 34.661 1.00 59.47 ? 54 SER K CB 1 +ATOM 19467 O OG . SER K 1 54 ? 46.992 44.206 35.161 1.00 46.75 ? 54 SER K OG 1 +ATOM 19468 N N . ASN K 1 55 ? 46.597 45.726 37.711 1.00 106.44 ? 55 ASN K N 1 +ATOM 19469 C CA . ASN K 1 55 ? 46.533 45.148 39.045 1.00 83.18 ? 55 ASN K CA 1 +ATOM 19470 C C . ASN K 1 55 ? 47.366 43.881 39.142 1.00 77.71 ? 55 ASN K C 1 +ATOM 19471 O O . ASN K 1 55 ? 47.936 43.542 40.206 1.00 87.02 ? 55 ASN K O 1 +ATOM 19472 C CB . ASN K 1 55 ? 45.089 44.831 39.360 1.00 73.08 ? 55 ASN K CB 1 +ATOM 19473 C CG . ASN K 1 55 ? 44.867 44.577 40.814 1.00 103.30 ? 55 ASN K CG 1 +ATOM 19474 O OD1 . ASN K 1 55 ? 45.656 44.958 41.680 1.00 121.84 ? 55 ASN K OD1 1 +ATOM 19475 N ND2 . ASN K 1 55 ? 43.758 43.953 41.098 1.00 142.06 ? 55 ASN K ND2 1 +ATOM 19476 N N . PHE K 1 56 ? 47.469 43.200 38.002 1.00 80.12 ? 56 PHE K N 1 +ATOM 19477 C CA . PHE K 1 56 ? 48.042 41.856 37.941 1.00 79.58 ? 56 PHE K CA 1 +ATOM 19478 C C . PHE K 1 56 ? 49.499 41.875 37.512 1.00 94.88 ? 56 PHE K C 1 +ATOM 19479 O O . PHE K 1 56 ? 50.102 40.811 37.320 1.00 91.18 ? 56 PHE K O 1 +ATOM 19480 C CB . PHE K 1 56 ? 47.301 41.000 36.919 1.00 87.30 ? 56 PHE K CB 1 +ATOM 19481 C CG . PHE K 1 56 ? 45.856 40.834 37.199 1.00 88.97 ? 56 PHE K CG 1 +ATOM 19482 C CD1 . PHE K 1 56 ? 45.412 40.255 38.369 1.00 96.03 ? 56 PHE K CD1 1 +ATOM 19483 C CD2 . PHE K 1 56 ? 44.937 41.292 36.295 1.00 104.74 ? 56 PHE K CD2 1 +ATOM 19484 C CE1 . PHE K 1 56 ? 44.062 40.171 38.652 1.00 99.09 ? 56 PHE K CE1 1 +ATOM 19485 C CE2 . PHE K 1 56 ? 43.584 41.182 36.558 1.00 111.89 ? 56 PHE K CE2 1 +ATOM 19486 C CZ . PHE K 1 56 ? 43.147 40.623 37.743 1.00 95.28 ? 56 PHE K CZ 1 +ATOM 19487 N N . SER K 1 57 ? 50.047 43.049 37.218 1.00 98.63 ? 57 SER K N 1 +ATOM 19488 C CA . SER K 1 57 ? 51.435 43.101 36.791 1.00 108.50 ? 57 SER K CA 1 +ATOM 19489 C C . SER K 1 57 ? 52.331 42.854 37.995 1.00 94.56 ? 57 SER K C 1 +ATOM 19490 O O . SER K 1 57 ? 52.385 43.655 38.944 1.00 131.68 ? 57 SER K O 1 +ATOM 19491 C CB . SER K 1 57 ? 51.750 44.438 36.107 1.00 157.27 ? 57 SER K CB 1 +ATOM 19492 O OG . SER K 1 57 ? 51.190 44.462 34.802 1.00 182.26 ? 57 SER K OG 1 +ATOM 19493 N N . THR K 1 58 ? 53.034 41.739 37.967 1.00 79.82 ? 58 THR K N 1 +ATOM 19494 C CA . THR K 1 58 ? 53.982 41.452 39.019 1.00 112.15 ? 58 THR K CA 1 +ATOM 19495 C C . THR K 1 58 ? 55.162 42.404 39.031 1.00 108.16 ? 58 THR K C 1 +ATOM 19496 O O . THR K 1 58 ? 55.609 42.907 38.012 1.00 111.74 ? 58 THR K O 1 +ATOM 19497 C CB . THR K 1 58 ? 54.547 40.053 38.852 1.00 126.97 ? 58 THR K CB 1 +ATOM 19498 O OG1 . THR K 1 58 ? 55.258 39.971 37.617 1.00 101.17 ? 58 THR K OG1 1 +ATOM 19499 C CG2 . THR K 1 58 ? 53.422 39.071 38.825 1.00 139.33 ? 58 THR K CG2 1 +ATOM 19500 N N . ALA K 1 59 ? 55.739 42.595 40.190 1.00 102.76 ? 59 ALA K N 1 +ATOM 19501 C CA . ALA K 1 59 ? 56.832 43.526 40.244 1.00 111.10 ? 59 ALA K CA 1 +ATOM 19502 C C . ALA K 1 59 ? 58.092 42.919 39.651 1.00 82.28 ? 59 ALA K C 1 +ATOM 19503 O O . ALA K 1 59 ? 59.023 43.642 39.316 1.00 78.61 ? 59 ALA K O 1 +ATOM 19504 C CB . ALA K 1 59 ? 57.062 43.989 41.666 1.00 135.71 ? 59 ALA K CB 1 +ATOM 19505 N N . VAL K 1 60 ? 58.115 41.601 39.527 1.00 67.04 ? 60 VAL K N 1 +ATOM 19506 C CA . VAL K 1 60 ? 59.326 40.902 39.182 1.00 78.56 ? 60 VAL K CA 1 +ATOM 19507 C C . VAL K 1 60 ? 58.971 39.858 38.161 1.00 68.69 ? 60 VAL K C 1 +ATOM 19508 O O . VAL K 1 60 ? 57.936 39.211 38.279 1.00 74.65 ? 60 VAL K O 1 +ATOM 19509 C CB . VAL K 1 60 ? 59.934 40.196 40.415 1.00 99.50 ? 60 VAL K CB 1 +ATOM 19510 C CG1 . VAL K 1 60 ? 61.196 39.409 40.062 1.00 102.76 ? 60 VAL K CG1 1 +ATOM 19511 C CG2 . VAL K 1 60 ? 60.248 41.201 41.519 1.00 113.27 ? 60 VAL K CG2 1 +ATOM 19512 N N . PRO K 1 61 ? 59.866 39.624 37.195 1.00 53.99 ? 61 PRO K N 1 +ATOM 19513 C CA . PRO K 1 61 ? 59.505 38.691 36.146 1.00 61.12 ? 61 PRO K CA 1 +ATOM 19514 C C . PRO K 1 61 ? 59.514 37.272 36.682 1.00 67.73 ? 61 PRO K C 1 +ATOM 19515 O O . PRO K 1 61 ? 60.321 36.954 37.567 1.00 41.33 ? 61 PRO K O 1 +ATOM 19516 C CB . PRO K 1 61 ? 60.601 38.877 35.103 1.00 51.48 ? 61 PRO K CB 1 +ATOM 19517 C CG . PRO K 1 61 ? 61.708 39.526 35.839 1.00 46.88 ? 61 PRO K CG 1 +ATOM 19518 C CD . PRO K 1 61 ? 61.040 40.410 36.827 1.00 52.15 ? 61 PRO K CD 1 +ATOM 19519 N N . GLN K 1 62 ? 58.619 36.437 36.133 1.00 58.52 ? 62 GLN K N 1 +ATOM 19520 C CA . GLN K 1 62 ? 58.422 35.094 36.640 1.00 56.69 ? 62 GLN K CA 1 +ATOM 19521 C C . GLN K 1 62 ? 59.339 34.153 35.924 1.00 47.90 ? 62 GLN K C 1 +ATOM 19522 O O . GLN K 1 62 ? 58.990 33.007 35.704 1.00 78.39 ? 62 GLN K O 1 +ATOM 19523 C CB . GLN K 1 62 ? 56.973 34.644 36.409 1.00 90.67 ? 62 GLN K CB 1 +ATOM 19524 C CG . GLN K 1 62 ? 55.900 35.617 36.892 1.00 89.74 ? 62 GLN K CG 1 +ATOM 19525 C CD . GLN K 1 62 ? 56.009 35.898 38.369 1.00 85.87 ? 62 GLN K CD 1 +ATOM 19526 O OE1 . GLN K 1 62 ? 55.628 35.082 39.204 1.00 80.23 ? 62 GLN K OE1 1 +ATOM 19527 N NE2 . GLN K 1 62 ? 56.602 37.027 38.702 1.00 105.47 ? 62 GLN K NE2 1 +ATOM 19528 N N . SER K 1 63 ? 60.536 34.599 35.629 1.00 51.98 ? 63 SER K N 1 +ATOM 19529 C CA . SER K 1 63 ? 61.378 33.920 34.675 1.00 69.46 ? 63 SER K CA 1 +ATOM 19530 C C . SER K 1 63 ? 62.719 33.495 35.283 1.00 88.16 ? 63 SER K C 1 +ATOM 19531 O O . SER K 1 63 ? 63.641 33.065 34.572 1.00 99.07 ? 63 SER K O 1 +ATOM 19532 C CB . SER K 1 63 ? 61.596 34.841 33.468 1.00 96.59 ? 63 SER K CB 1 +ATOM 19533 O OG . SER K 1 63 ? 62.266 36.055 33.789 1.00 95.17 ? 63 SER K OG 1 +ATOM 19534 N N . ALA K 1 64 ? 62.816 33.594 36.607 1.00 85.32 ? 64 ALA K N 1 +ATOM 19535 C CA . ALA K 1 64 ? 64.076 33.380 37.308 1.00 109.20 ? 64 ALA K CA 1 +ATOM 19536 C C . ALA K 1 64 ? 64.711 32.005 37.035 1.00 84.49 ? 64 ALA K C 1 +ATOM 19537 O O . ALA K 1 64 ? 65.939 31.877 36.878 1.00 108.33 ? 64 ALA K O 1 +ATOM 19538 C CB . ALA K 1 64 ? 63.853 33.569 38.797 1.00 118.09 ? 64 ALA K CB 1 +ATOM 19539 N N . THR K 1 65 ? 63.870 30.996 36.987 1.00 64.78 ? 65 THR K N 1 +ATOM 19540 C CA . THR K 1 65 ? 64.305 29.656 36.707 1.00 76.87 ? 65 THR K CA 1 +ATOM 19541 C C . THR K 1 65 ? 65.217 29.589 35.489 1.00 71.14 ? 65 THR K C 1 +ATOM 19542 O O . THR K 1 65 ? 66.249 28.933 35.499 1.00 55.65 ? 65 THR K O 1 +ATOM 19543 C CB . THR K 1 65 ? 63.076 28.766 36.445 1.00 108.72 ? 65 THR K CB 1 +ATOM 19544 O OG1 . THR K 1 65 ? 62.018 29.163 37.331 1.00 145.22 ? 65 THR K OG1 1 +ATOM 19545 C CG2 . THR K 1 65 ? 63.407 27.274 36.640 1.00 89.11 ? 65 THR K CG2 1 +ATOM 19546 N N . ALA K 1 66 ? 64.750 30.155 34.388 1.00 104.93 ? 66 ALA K N 1 +ATOM 19547 C CA . ALA K 1 66 ? 65.448 29.997 33.133 1.00 120.14 ? 66 ALA K CA 1 +ATOM 19548 C C . ALA K 1 66 ? 66.751 30.783 33.215 1.00 90.21 ? 66 ALA K C 1 +ATOM 19549 O O . ALA K 1 66 ? 67.753 30.404 32.579 1.00 124.39 ? 66 ALA K O 1 +ATOM 19550 C CB . ALA K 1 66 ? 64.555 30.453 31.973 1.00 140.66 ? 66 ALA K CB 1 +ATOM 19551 N N . MET K 1 67 ? 66.704 31.917 33.917 1.00 63.36 ? 67 MET K N 1 +ATOM 19552 C CA . MET K 1 67 ? 67.891 32.768 34.050 1.00 84.29 ? 67 MET K CA 1 +ATOM 19553 C C . MET K 1 67 ? 68.982 32.007 34.809 1.00 81.29 ? 67 MET K C 1 +ATOM 19554 O O . MET K 1 67 ? 70.163 32.044 34.459 1.00 56.80 ? 67 MET K O 1 +ATOM 19555 C CB . MET K 1 67 ? 67.558 34.066 34.789 1.00 88.35 ? 67 MET K CB 1 +ATOM 19556 C CG . MET K 1 67 ? 66.720 35.075 34.022 1.00 83.36 ? 67 MET K CG 1 +ATOM 19557 S SD . MET K 1 67 ? 66.123 36.384 35.116 1.00 100.32 ? 67 MET K SD 1 +ATOM 19558 C CE . MET K 1 67 ? 65.358 37.499 33.941 1.00 122.93 ? 67 MET K CE 1 +ATOM 19559 N N . LEU K 1 68 ? 68.562 31.284 35.837 1.00 82.91 ? 68 LEU K N 1 +ATOM 19560 C CA . LEU K 1 68 ? 69.499 30.517 36.624 1.00 76.44 ? 68 LEU K CA 1 +ATOM 19561 C C . LEU K 1 68 ? 70.105 29.430 35.766 1.00 91.32 ? 68 LEU K C 1 +ATOM 19562 O O . LEU K 1 68 ? 71.295 29.166 35.866 1.00 84.86 ? 68 LEU K O 1 +ATOM 19563 C CB . LEU K 1 68 ? 68.823 29.885 37.845 1.00 89.76 ? 68 LEU K CB 1 +ATOM 19564 C CG . LEU K 1 68 ? 69.702 28.862 38.583 1.00 89.52 ? 68 LEU K CG 1 +ATOM 19565 C CD1 . LEU K 1 68 ? 70.906 29.547 39.205 1.00 87.89 ? 68 LEU K CD1 1 +ATOM 19566 C CD2 . LEU K 1 68 ? 68.935 28.089 39.648 1.00 95.94 ? 68 LEU K CD2 1 +ATOM 19567 N N . VAL K 1 69 ? 69.270 28.724 34.997 1.00 102.88 ? 69 VAL K N 1 +ATOM 19568 C CA . VAL K 1 69 ? 69.768 27.611 34.185 1.00 90.20 ? 69 VAL K CA 1 +ATOM 19569 C C . VAL K 1 69 ? 70.815 28.170 33.233 1.00 86.53 ? 69 VAL K C 1 +ATOM 19570 O O . VAL K 1 69 ? 71.862 27.561 32.997 1.00 80.99 ? 69 VAL K O 1 +ATOM 19571 C CB . VAL K 1 69 ? 68.644 26.903 33.392 1.00 66.61 ? 69 VAL K CB 1 +ATOM 19572 C CG1 . VAL K 1 69 ? 69.250 25.897 32.420 1.00 64.62 ? 69 VAL K CG1 1 +ATOM 19573 C CG2 . VAL K 1 69 ? 67.682 26.167 34.311 1.00 83.74 ? 69 VAL K CG2 1 +ATOM 19574 N N . THR K 1 70 ? 70.496 29.319 32.654 1.00 68.55 ? 70 THR K N 1 +ATOM 19575 C CA . THR K 1 70 ? 71.360 29.923 31.667 1.00 65.77 ? 70 THR K CA 1 +ATOM 19576 C C . THR K 1 70 ? 72.669 30.282 32.337 1.00 78.41 ? 70 THR K C 1 +ATOM 19577 O O . THR K 1 70 ? 73.754 30.109 31.752 1.00 86.56 ? 70 THR K O 1 +ATOM 19578 C CB . THR K 1 70 ? 70.672 31.152 31.034 1.00 66.30 ? 70 THR K CB 1 +ATOM 19579 O OG1 . THR K 1 70 ? 69.429 30.737 30.450 1.00 88.51 ? 70 THR K OG1 1 +ATOM 19580 C CG2 . THR K 1 70 ? 71.549 31.781 29.949 1.00 77.84 ? 70 THR K CG2 1 +ATOM 19581 N N . ALA K 1 71 ? 72.575 30.897 33.515 1.00 84.92 ? 71 ALA K N 1 +ATOM 19582 C CA . ALA K 1 71 ? 73.788 31.327 34.225 1.00 100.73 ? 71 ALA K CA 1 +ATOM 19583 C C . ALA K 1 71 ? 74.650 30.098 34.558 1.00 100.71 ? 71 ALA K C 1 +ATOM 19584 O O . ALA K 1 71 ? 75.878 30.131 34.454 1.00 59.01 ? 71 ALA K O 1 +ATOM 19585 C CB . ALA K 1 71 ? 73.419 32.101 35.485 1.00 102.20 ? 71 ALA K CB 1 +ATOM 19586 N N . LEU K 1 72 ? 73.989 29.014 34.959 1.00 120.40 ? 72 LEU K N 1 +ATOM 19587 C CA . LEU K 1 72 ? 74.691 27.773 35.292 1.00 135.69 ? 72 LEU K CA 1 +ATOM 19588 C C . LEU K 1 72 ? 75.407 27.222 34.074 1.00 165.39 ? 72 LEU K C 1 +ATOM 19589 O O . LEU K 1 72 ? 76.403 26.518 34.208 1.00 152.18 ? 72 LEU K O 1 +ATOM 19590 C CB . LEU K 1 72 ? 73.717 26.721 35.826 1.00 119.47 ? 72 LEU K CB 1 +ATOM 19591 C CG . LEU K 1 72 ? 73.119 27.016 37.196 1.00 96.85 ? 72 LEU K CG 1 +ATOM 19592 C CD1 . LEU K 1 72 ? 71.897 26.144 37.408 1.00 77.25 ? 72 LEU K CD1 1 +ATOM 19593 C CD2 . LEU K 1 72 ? 74.130 26.795 38.311 1.00 100.90 ? 72 LEU K CD2 1 +ATOM 19594 N N . LYS K 1 73 ? 74.891 27.531 32.884 1.00 164.46 ? 73 LYS K N 1 +ATOM 19595 C CA . LYS K 1 73 ? 75.526 27.067 31.647 1.00 145.53 ? 73 LYS K CA 1 +ATOM 19596 C C . LYS K 1 73 ? 76.670 27.960 31.219 1.00 138.24 ? 73 LYS K C 1 +ATOM 19597 O O . LYS K 1 73 ? 77.745 27.470 30.870 1.00 115.35 ? 73 LYS K O 1 +ATOM 19598 C CB . LYS K 1 73 ? 74.527 26.978 30.502 1.00 126.48 ? 73 LYS K CB 1 +ATOM 19599 C CG . LYS K 1 73 ? 75.056 26.206 29.291 1.00 113.76 ? 73 LYS K CG 1 +ATOM 19600 C CD . LYS K 1 73 ? 74.010 26.125 28.172 1.00 129.99 ? 73 LYS K CD 1 +ATOM 19601 C CE . LYS K 1 73 ? 74.649 25.996 26.798 1.00 156.58 ? 73 LYS K CE 1 +ATOM 19602 N NZ . LYS K 1 73 ? 74.384 24.687 26.137 1.00 165.31 ? 73 LYS K NZ 1 +ATOM 19603 N N . ASP K 1 74 ? 76.442 29.271 31.256 1.00 139.10 ? 74 ASP K N 1 +ATOM 19604 C CA . ASP K 1 74 ? 77.458 30.239 30.828 1.00 139.72 ? 74 ASP K CA 1 +ATOM 19605 C C . ASP K 1 74 ? 78.749 30.133 31.651 1.00 154.52 ? 74 ASP K C 1 +ATOM 19606 O O . ASP K 1 74 ? 79.835 30.428 31.143 1.00 148.46 ? 74 ASP K O 1 +ATOM 19607 C CB . ASP K 1 74 ? 76.915 31.666 30.911 1.00 111.38 ? 74 ASP K CB 1 +ATOM 19608 C CG . ASP K 1 74 ? 75.817 31.950 29.883 1.00 111.48 ? 74 ASP K CG 1 +ATOM 19609 O OD1 . ASP K 1 74 ? 75.787 31.322 28.792 1.00 92.75 ? 74 ASP K OD1 1 +ATOM 19610 O OD2 . ASP K 1 74 ? 74.959 32.819 30.185 1.00 108.40 ? 74 ASP K OD2 1 +ATOM 19611 N N . SER K 1 75 ? 78.624 29.687 32.907 1.00 157.40 ? 75 SER K N 1 +ATOM 19612 C CA . SER K 1 75 ? 79.766 29.585 33.830 1.00 139.62 ? 75 SER K CA 1 +ATOM 19613 C C . SER K 1 75 ? 80.803 28.562 33.374 1.00 114.09 ? 75 SER K C 1 +ATOM 19614 O O . SER K 1 75 ? 81.972 28.652 33.734 1.00 86.22 ? 75 SER K O 1 +ATOM 19615 C CB . SER K 1 75 ? 79.290 29.215 35.235 1.00 145.79 ? 75 SER K CB 1 +ATOM 19616 O OG . SER K 1 75 ? 79.160 27.810 35.379 1.00 149.44 ? 75 SER K OG 1 +ATOM 19617 N N . ARG K 1 76 ? 80.352 27.590 32.584 1.00 138.09 ? 76 ARG K N 1 +ATOM 19618 C CA . ARG K 1 76 ? 81.186 26.489 32.092 1.00 140.14 ? 76 ARG K CA 1 +ATOM 19619 C C . ARG K 1 76 ? 81.701 25.663 33.247 1.00 105.80 ? 76 ARG K C 1 +ATOM 19620 O O . ARG K 1 76 ? 82.814 25.140 33.209 1.00 86.45 ? 76 ARG K O 1 +ATOM 19621 C CB . ARG K 1 76 ? 82.341 26.997 31.234 1.00 151.44 ? 76 ARG K CB 1 +ATOM 19622 C CG . ARG K 1 76 ? 81.923 27.758 29.975 1.00 151.66 ? 76 ARG K CG 1 +ATOM 19623 C CD . ARG K 1 76 ? 83.153 28.184 29.180 1.00 137.61 ? 76 ARG K CD 1 +ATOM 19624 N NE . ARG K 1 76 ? 83.916 29.221 29.868 1.00 130.43 ? 76 ARG K NE 1 +ATOM 19625 C CZ . ARG K 1 76 ? 84.939 29.007 30.698 1.00 135.08 ? 76 ARG K CZ 1 +ATOM 19626 N NH1 . ARG K 1 76 ? 85.395 27.781 30.946 1.00 137.09 ? 76 ARG K NH1 1 +ATOM 19627 N NH2 . ARG K 1 76 ? 85.510 30.040 31.301 1.00 132.00 ? 76 ARG K NH2 1 +ATOM 19628 N N . TRP K 1 77 ? 80.848 25.521 34.255 1.00 94.84 ? 77 TRP K N 1 +ATOM 19629 C CA . TRP K 1 77 ? 81.073 24.583 35.341 1.00 105.49 ? 77 TRP K CA 1 +ATOM 19630 C C . TRP K 1 77 ? 80.021 23.462 35.344 1.00 99.86 ? 77 TRP K C 1 +ATOM 19631 O O . TRP K 1 77 ? 80.309 22.320 35.730 1.00 68.80 ? 77 TRP K O 1 +ATOM 19632 C CB . TRP K 1 77 ? 81.031 25.338 36.662 1.00 114.97 ? 77 TRP K CB 1 +ATOM 19633 C CG . TRP K 1 77 ? 82.361 25.823 37.122 1.00 121.41 ? 77 TRP K CG 1 +ATOM 19634 C CD1 . TRP K 1 77 ? 83.036 26.909 36.660 1.00 142.15 ? 77 TRP K CD1 1 +ATOM 19635 C CD2 . TRP K 1 77 ? 83.150 25.278 38.182 1.00 102.11 ? 77 TRP K CD2 1 +ATOM 19636 N NE1 . TRP K 1 77 ? 84.201 27.072 37.361 1.00 137.16 ? 77 TRP K NE1 1 +ATOM 19637 C CE2 . TRP K 1 77 ? 84.290 26.085 38.307 1.00 105.66 ? 77 TRP K CE2 1 +ATOM 19638 C CE3 . TRP K 1 77 ? 82.998 24.192 39.040 1.00 99.98 ? 77 TRP K CE3 1 +ATOM 19639 C CZ2 . TRP K 1 77 ? 85.279 25.828 39.233 1.00 92.29 ? 77 TRP K CZ2 1 +ATOM 19640 C CZ3 . TRP K 1 77 ? 83.971 23.954 39.978 1.00 108.16 ? 77 TRP K CZ3 1 +ATOM 19641 C CH2 . TRP K 1 77 ? 85.103 24.763 40.063 1.00 103.07 ? 77 TRP K CH2 1 +ATOM 19642 N N . PHE K 1 78 ? 78.803 23.811 34.932 1.00 109.61 ? 78 PHE K N 1 +ATOM 19643 C CA . PHE K 1 78 ? 77.653 22.912 35.004 1.00 123.29 ? 78 PHE K CA 1 +ATOM 19644 C C . PHE K 1 78 ? 77.018 22.631 33.631 1.00 139.23 ? 78 PHE K C 1 +ATOM 19645 O O . PHE K 1 78 ? 76.936 23.510 32.782 1.00 129.75 ? 78 PHE K O 1 +ATOM 19646 C CB . PHE K 1 78 ? 76.582 23.545 35.863 1.00 113.25 ? 78 PHE K CB 1 +ATOM 19647 C CG . PHE K 1 78 ? 77.058 23.944 37.202 1.00 96.69 ? 78 PHE K CG 1 +ATOM 19648 C CD1 . PHE K 1 78 ? 77.284 22.976 38.189 1.00 101.65 ? 78 PHE K CD1 1 +ATOM 19649 C CD2 . PHE K 1 78 ? 77.238 25.282 37.507 1.00 68.37 ? 78 PHE K CD2 1 +ATOM 19650 C CE1 . PHE K 1 78 ? 77.731 23.337 39.451 1.00 95.79 ? 78 PHE K CE1 1 +ATOM 19651 C CE2 . PHE K 1 78 ? 77.650 25.649 38.776 1.00 83.27 ? 78 PHE K CE2 1 +ATOM 19652 C CZ . PHE K 1 78 ? 77.915 24.679 39.748 1.00 78.31 ? 78 PHE K CZ 1 +ATOM 19653 N N . ILE K 1 79 ? 76.561 21.399 33.448 1.00 126.49 ? 79 ILE K N 1 +ATOM 19654 C CA . ILE K 1 79 ? 75.641 21.043 32.384 1.00 80.90 ? 79 ILE K CA 1 +ATOM 19655 C C . ILE K 1 79 ? 74.270 21.030 33.024 1.00 76.16 ? 79 ILE K C 1 +ATOM 19656 O O . ILE K 1 79 ? 74.023 20.336 34.024 1.00 89.69 ? 79 ILE K O 1 +ATOM 19657 C CB . ILE K 1 79 ? 75.917 19.619 31.875 1.00 106.14 ? 79 ILE K CB 1 +ATOM 19658 C CG1 . ILE K 1 79 ? 77.411 19.427 31.573 1.00 104.85 ? 79 ILE K CG1 1 +ATOM 19659 C CG2 . ILE K 1 79 ? 75.082 19.307 30.636 1.00 121.43 ? 79 ILE K CG2 1 +ATOM 19660 C CD1 . ILE K 1 79 ? 77.876 17.977 31.604 1.00 93.61 ? 79 ILE K CD1 1 +ATOM 19661 N N . PRO K 1 80 ? 73.383 21.850 32.515 1.00 78.96 ? 80 PRO K N 1 +ATOM 19662 C CA . PRO K 1 80 ? 72.035 21.768 33.034 1.00 95.98 ? 80 PRO K CA 1 +ATOM 19663 C C . PRO K 1 80 ? 71.182 20.709 32.349 1.00 92.38 ? 80 PRO K C 1 +ATOM 19664 O O . PRO K 1 80 ? 71.164 20.623 31.130 1.00 72.81 ? 80 PRO K O 1 +ATOM 19665 C CB . PRO K 1 80 ? 71.476 23.176 32.772 1.00 83.63 ? 80 PRO K CB 1 +ATOM 19666 C CG . PRO K 1 80 ? 72.692 24.023 32.636 1.00 71.33 ? 80 PRO K CG 1 +ATOM 19667 C CD . PRO K 1 80 ? 73.624 23.137 31.875 1.00 77.28 ? 80 PRO K CD 1 +ATOM 19668 N N . LEU K 1 81 ? 70.493 19.906 33.154 1.00 93.26 ? 81 LEU K N 1 +ATOM 19669 C CA . LEU K 1 81 ? 69.514 18.950 32.655 1.00 82.52 ? 81 LEU K CA 1 +ATOM 19670 C C . LEU K 1 81 ? 68.111 19.514 32.726 1.00 71.48 ? 81 LEU K C 1 +ATOM 19671 O O . LEU K 1 81 ? 67.816 20.356 33.605 1.00 86.28 ? 81 LEU K O 1 +ATOM 19672 C CB . LEU K 1 81 ? 69.586 17.696 33.473 1.00 91.52 ? 81 LEU K CB 1 +ATOM 19673 C CG . LEU K 1 81 ? 71.015 17.147 33.529 1.00 139.23 ? 81 LEU K CG 1 +ATOM 19674 C CD1 . LEU K 1 81 ? 71.024 15.964 34.454 1.00 138.82 ? 81 LEU K CD1 1 +ATOM 19675 C CD2 . LEU K 1 81 ? 71.477 16.740 32.148 1.00 175.65 ? 81 LEU K CD2 1 +ATOM 19676 N N . GLU K 1 82 ? 67.344 19.227 31.680 1.00 71.23 ? 82 GLU K N 1 +ATOM 19677 C CA . GLU K 1 82 ? 66.069 19.917 31.443 1.00 101.93 ? 82 GLU K CA 1 +ATOM 19678 C C . GLU K 1 82 ? 65.020 19.247 32.288 1.00 124.27 ? 82 GLU K C 1 +ATOM 19679 O O . GLU K 1 82 ? 64.614 18.113 32.014 1.00 160.56 ? 82 GLU K O 1 +ATOM 19680 C CB . GLU K 1 82 ? 65.640 19.922 29.941 1.00 111.27 ? 82 GLU K CB 1 +ATOM 19681 C CG . GLU K 1 82 ? 64.252 20.537 29.640 1.00 92.94 ? 82 GLU K CG 1 +ATOM 19682 C CD . GLU K 1 82 ? 64.164 22.069 29.809 1.00 101.26 ? 82 GLU K CD 1 +ATOM 19683 O OE1 . GLU K 1 82 ? 64.636 22.637 30.857 1.00 179.19 ? 82 GLU K OE1 1 +ATOM 19684 O OE2 . GLU K 1 82 ? 63.604 22.728 28.904 1.00 53.73 ? 82 GLU K OE2 1 +ATOM 19685 N N . ARG K 1 83 ? 64.559 19.995 33.284 1.00 110.79 ? 83 ARG K N 1 +ATOM 19686 C CA . ARG K 1 83 ? 63.459 19.565 34.120 1.00 80.61 ? 83 ARG K CA 1 +ATOM 19687 C C . ARG K 1 83 ? 62.308 20.571 34.127 1.00 69.85 ? 83 ARG K C 1 +ATOM 19688 O O . ARG K 1 83 ? 61.194 20.224 34.486 1.00 94.72 ? 83 ARG K O 1 +ATOM 19689 C CB . ARG K 1 83 ? 63.975 19.305 35.543 1.00 82.24 ? 83 ARG K CB 1 +ATOM 19690 C CG . ARG K 1 83 ? 65.102 18.287 35.633 1.00 65.80 ? 83 ARG K CG 1 +ATOM 19691 C CD . ARG K 1 83 ? 64.638 16.879 35.292 1.00 56.41 ? 83 ARG K CD 1 +ATOM 19692 N NE . ARG K 1 83 ? 65.685 15.937 35.639 1.00 54.16 ? 83 ARG K NE 1 +ATOM 19693 C CZ . ARG K 1 83 ? 66.556 15.415 34.792 1.00 59.91 ? 83 ARG K CZ 1 +ATOM 19694 N NH1 . ARG K 1 83 ? 66.419 15.605 33.475 1.00 59.89 ? 83 ARG K NH1 1 +ATOM 19695 N NH2 . ARG K 1 83 ? 67.589 14.696 35.264 1.00 54.58 ? 83 ARG K NH2 1 +ATOM 19696 N N . GLN K 1 84 ? 62.546 21.834 33.787 1.00 77.23 ? 84 GLN K N 1 +ATOM 19697 C CA . GLN K 1 84 ? 61.420 22.805 33.765 1.00 92.21 ? 84 GLN K CA 1 +ATOM 19698 C C . GLN K 1 84 ? 60.312 22.320 32.836 1.00 99.06 ? 84 GLN K C 1 +ATOM 19699 O O . GLN K 1 84 ? 59.145 22.389 33.169 1.00 99.69 ? 84 GLN K O 1 +ATOM 19700 C CB . GLN K 1 84 ? 61.860 24.228 33.374 1.00 104.04 ? 84 GLN K CB 1 +ATOM 19701 C CG . GLN K 1 84 ? 61.038 25.339 34.007 1.00 97.16 ? 84 GLN K CG 1 +ATOM 19702 C CD . GLN K 1 84 ? 61.451 26.714 33.500 1.00 129.39 ? 84 GLN K CD 1 +ATOM 19703 O OE1 . GLN K 1 84 ? 62.639 26.992 33.304 1.00 182.34 ? 84 GLN K OE1 1 +ATOM 19704 N NE2 . GLN K 1 84 ? 60.483 27.613 33.380 1.00 152.03 ? 84 GLN K NE2 1 +ATOM 19705 N N . GLY K 1 85 ? 60.674 21.756 31.695 1.00 107.56 ? 85 GLY K N 1 +ATOM 19706 C CA . GLY K 1 85 ? 59.649 21.254 30.802 1.00 111.35 ? 85 GLY K CA 1 +ATOM 19707 C C . GLY K 1 85 ? 59.670 19.748 30.710 1.00 105.62 ? 85 GLY K C 1 +ATOM 19708 O O . GLY K 1 85 ? 59.448 19.198 29.629 1.00 107.18 ? 85 GLY K O 1 +ATOM 19709 N N . LEU K 1 86 ? 59.870 19.076 31.844 1.00 100.72 ? 86 LEU K N 1 +ATOM 19710 C CA . LEU K 1 86 ? 60.129 17.634 31.846 1.00 106.53 ? 86 LEU K CA 1 +ATOM 19711 C C . LEU K 1 86 ? 58.990 16.841 31.189 1.00 92.97 ? 86 LEU K C 1 +ATOM 19712 O O . LEU K 1 86 ? 59.236 15.850 30.497 1.00 89.84 ? 86 LEU K O 1 +ATOM 19713 C CB . LEU K 1 86 ? 60.369 17.113 33.270 1.00 97.98 ? 86 LEU K CB 1 +ATOM 19714 C CG . LEU K 1 86 ? 60.493 15.605 33.515 1.00 101.59 ? 86 LEU K CG 1 +ATOM 19715 C CD1 . LEU K 1 86 ? 61.655 14.983 32.754 1.00 121.75 ? 86 LEU K CD1 1 +ATOM 19716 C CD2 . LEU K 1 86 ? 60.656 15.343 35.004 1.00 98.93 ? 86 LEU K CD2 1 +ATOM 19717 N N . GLN K 1 87 ? 57.767 17.324 31.341 1.00 81.22 ? 87 GLN K N 1 +ATOM 19718 C CA . GLN K 1 87 ? 56.614 16.589 30.855 1.00 101.19 ? 87 GLN K CA 1 +ATOM 19719 C C . GLN K 1 87 ? 56.654 16.443 29.326 1.00 100.83 ? 87 GLN K C 1 +ATOM 19720 O O . GLN K 1 87 ? 56.392 15.358 28.759 1.00 93.63 ? 87 GLN K O 1 +ATOM 19721 C CB . GLN K 1 87 ? 55.319 17.268 31.332 1.00 114.71 ? 87 GLN K CB 1 +ATOM 19722 C CG . GLN K 1 87 ? 54.168 16.297 31.612 1.00 114.20 ? 87 GLN K CG 1 +ATOM 19723 C CD . GLN K 1 87 ? 54.586 15.035 32.376 1.00 113.15 ? 87 GLN K CD 1 +ATOM 19724 O OE1 . GLN K 1 87 ? 55.172 15.109 33.463 1.00 116.76 ? 87 GLN K OE1 1 +ATOM 19725 N NE2 . GLN K 1 87 ? 54.313 13.869 31.792 1.00 104.81 ? 87 GLN K NE2 1 +ATOM 19726 N N . ASN K 1 88 ? 57.007 17.533 28.653 1.00 83.63 ? 88 ASN K N 1 +ATOM 19727 C CA . ASN K 1 88 ? 57.102 17.519 27.192 1.00 79.95 ? 88 ASN K CA 1 +ATOM 19728 C C . ASN K 1 88 ? 58.191 16.573 26.708 1.00 79.63 ? 88 ASN K C 1 +ATOM 19729 O O . ASN K 1 88 ? 58.113 15.972 25.621 1.00 55.33 ? 88 ASN K O 1 +ATOM 19730 C CB . ASN K 1 88 ? 57.401 18.915 26.693 1.00 68.49 ? 88 ASN K CB 1 +ATOM 19731 C CG . ASN K 1 88 ? 56.398 19.893 27.183 1.00 75.15 ? 88 ASN K CG 1 +ATOM 19732 O OD1 . ASN K 1 88 ? 55.196 19.593 27.197 1.00 67.46 ? 88 ASN K OD1 1 +ATOM 19733 N ND2 . ASN K 1 88 ? 56.848 21.107 27.498 1.00 97.01 ? 88 ASN K ND2 1 +ATOM 19734 N N . LEU K 1 89 ? 59.258 16.522 27.491 1.00 73.88 ? 89 LEU K N 1 +ATOM 19735 C CA . LEU K 1 89 ? 60.419 15.755 27.126 1.00 68.63 ? 89 LEU K CA 1 +ATOM 19736 C C . LEU K 1 89 ? 59.951 14.302 27.100 1.00 56.47 ? 89 LEU K C 1 +ATOM 19737 O O . LEU K 1 89 ? 60.332 13.521 26.218 1.00 47.19 ? 89 LEU K O 1 +ATOM 19738 C CB . LEU K 1 89 ? 61.554 16.055 28.138 1.00 73.02 ? 89 LEU K CB 1 +ATOM 19739 C CG . LEU K 1 89 ? 63.012 15.932 27.713 1.00 77.22 ? 89 LEU K CG 1 +ATOM 19740 C CD1 . LEU K 1 89 ? 63.666 14.799 28.486 1.00 92.20 ? 89 LEU K CD1 1 +ATOM 19741 C CD2 . LEU K 1 89 ? 63.152 15.688 26.218 1.00 87.31 ? 89 LEU K CD2 1 +ATOM 19742 N N . LEU K 1 90 ? 59.149 13.948 28.097 1.00 63.74 ? 90 LEU K N 1 +ATOM 19743 C CA . LEU K 1 90 ? 58.765 12.550 28.289 1.00 70.50 ? 90 LEU K CA 1 +ATOM 19744 C C . LEU K 1 90 ? 57.759 12.178 27.224 1.00 70.28 ? 90 LEU K C 1 +ATOM 19745 O O . LEU K 1 90 ? 57.695 11.028 26.775 1.00 62.19 ? 90 LEU K O 1 +ATOM 19746 C CB . LEU K 1 90 ? 58.176 12.359 29.675 1.00 67.97 ? 90 LEU K CB 1 +ATOM 19747 C CG . LEU K 1 90 ? 59.125 12.651 30.834 1.00 68.85 ? 90 LEU K CG 1 +ATOM 19748 C CD1 . LEU K 1 90 ? 58.342 12.871 32.108 1.00 66.92 ? 90 LEU K CD1 1 +ATOM 19749 C CD2 . LEU K 1 90 ? 60.093 11.483 30.972 1.00 93.02 ? 90 LEU K CD2 1 +ATOM 19750 N N . ASN K 1 91 ? 57.005 13.181 26.784 1.00 71.71 ? 91 ASN K N 1 +ATOM 19751 C CA . ASN K 1 91 ? 56.038 13.004 25.700 1.00 84.69 ? 91 ASN K CA 1 +ATOM 19752 C C . ASN K 1 91 ? 56.714 12.749 24.346 1.00 71.68 ? 91 ASN K C 1 +ATOM 19753 O O . ASN K 1 91 ? 56.377 11.789 23.650 1.00 55.65 ? 91 ASN K O 1 +ATOM 19754 C CB . ASN K 1 91 ? 55.169 14.252 25.607 1.00 107.99 ? 91 ASN K CB 1 +ATOM 19755 C CG . ASN K 1 91 ? 53.712 14.011 25.882 1.00 116.41 ? 91 ASN K CG 1 +ATOM 19756 O OD1 . ASN K 1 91 ? 53.320 13.060 26.563 1.00 106.63 ? 91 ASN K OD1 1 +ATOM 19757 N ND2 . ASN K 1 91 ? 52.900 14.945 25.404 1.00 124.19 ? 91 ASN K ND2 1 +ATOM 19758 N N . GLU K 1 92 ? 57.698 13.576 23.998 1.00 71.07 ? 92 GLU K N 1 +ATOM 19759 C CA . GLU K 1 92 ? 58.485 13.331 22.773 1.00 70.20 ? 92 GLU K CA 1 +ATOM 19760 C C . GLU K 1 92 ? 59.151 11.952 22.781 1.00 58.19 ? 92 GLU K C 1 +ATOM 19761 O O . GLU K 1 92 ? 59.242 11.277 21.755 1.00 53.83 ? 92 GLU K O 1 +ATOM 19762 C CB . GLU K 1 92 ? 59.553 14.410 22.561 1.00 60.81 ? 92 GLU K CB 1 +ATOM 19763 C CG . GLU K 1 92 ? 59.080 15.586 21.721 1.00 65.00 ? 92 GLU K CG 1 +ATOM 19764 C CD . GLU K 1 92 ? 58.508 15.190 20.324 1.00 65.23 ? 92 GLU K CD 1 +ATOM 19765 O OE1 . GLU K 1 92 ? 59.160 14.519 19.526 1.00 55.47 ? 92 GLU K OE1 1 +ATOM 19766 O OE2 . GLU K 1 92 ? 57.382 15.542 20.007 1.00 43.37 ? 92 GLU K OE2 1 +ATOM 19767 N N . ARG K 1 93 ? 59.548 11.509 23.964 1.00 61.82 ? 93 ARG K N 1 +ATOM 19768 C CA . ARG K 1 93 ? 60.148 10.195 24.112 1.00 75.30 ? 93 ARG K CA 1 +ATOM 19769 C C . ARG K 1 93 ? 59.120 9.064 23.965 1.00 77.42 ? 93 ARG K C 1 +ATOM 19770 O O . ARG K 1 93 ? 59.405 8.029 23.356 1.00 64.33 ? 93 ARG K O 1 +ATOM 19771 C CB . ARG K 1 93 ? 60.919 10.123 25.441 1.00 72.49 ? 93 ARG K CB 1 +ATOM 19772 C CG . ARG K 1 93 ? 62.171 11.023 25.424 1.00 57.31 ? 93 ARG K CG 1 +ATOM 19773 C CD . ARG K 1 93 ? 62.783 11.248 26.764 1.00 44.68 ? 93 ARG K CD 1 +ATOM 19774 N NE . ARG K 1 93 ? 63.950 10.376 26.928 1.00 43.14 ? 93 ARG K NE 1 +ATOM 19775 C CZ . ARG K 1 93 ? 63.944 9.206 27.560 1.00 53.49 ? 93 ARG K CZ 1 +ATOM 19776 N NH1 . ARG K 1 93 ? 62.820 8.704 28.122 1.00 63.49 ? 93 ARG K NH1 1 +ATOM 19777 N NH2 . ARG K 1 93 ? 65.081 8.558 27.716 1.00 62.32 ? 93 ARG K NH2 1 +ATOM 19778 N N . LYS K 1 94 ? 57.891 9.319 24.381 1.00 94.96 ? 94 LYS K N 1 +ATOM 19779 C CA . LYS K 1 94 ? 56.805 8.391 24.073 1.00 107.55 ? 94 LYS K CA 1 +ATOM 19780 C C . LYS K 1 94 ? 56.608 8.258 22.561 1.00 90.90 ? 94 LYS K C 1 +ATOM 19781 O O . LYS K 1 94 ? 56.349 7.156 22.050 1.00 73.15 ? 94 LYS K O 1 +ATOM 19782 C CB . LYS K 1 94 ? 55.495 8.857 24.713 1.00 120.34 ? 94 LYS K CB 1 +ATOM 19783 C CG . LYS K 1 94 ? 55.278 8.398 26.147 1.00 138.07 ? 94 LYS K CG 1 +ATOM 19784 C CD . LYS K 1 94 ? 54.051 9.081 26.738 1.00 140.00 ? 94 LYS K CD 1 +ATOM 19785 C CE . LYS K 1 94 ? 53.484 8.353 27.951 1.00 132.77 ? 94 LYS K CE 1 +ATOM 19786 N NZ . LYS K 1 94 ? 52.538 9.236 28.687 1.00 125.61 ? 94 LYS K NZ 1 +ATOM 19787 N N . ILE K 1 95 ? 56.655 9.393 21.861 1.00 76.69 ? 95 ILE K N 1 +ATOM 19788 C CA . ILE K 1 95 ? 56.340 9.406 20.428 1.00 74.52 ? 95 ILE K CA 1 +ATOM 19789 C C . ILE K 1 95 ? 57.421 8.703 19.634 1.00 64.26 ? 95 ILE K C 1 +ATOM 19790 O O . ILE K 1 95 ? 57.129 7.987 18.668 1.00 53.31 ? 95 ILE K O 1 +ATOM 19791 C CB . ILE K 1 95 ? 56.150 10.826 19.848 1.00 72.06 ? 95 ILE K CB 1 +ATOM 19792 C CG1 . ILE K 1 95 ? 55.209 11.653 20.715 1.00 66.74 ? 95 ILE K CG1 1 +ATOM 19793 C CG2 . ILE K 1 95 ? 55.550 10.689 18.458 1.00 86.71 ? 95 ILE K CG2 1 +ATOM 19794 C CD1 . ILE K 1 95 ? 54.704 12.909 20.057 1.00 72.49 ? 95 ILE K CD1 1 +ATOM 19795 N N . ILE K 1 96 ? 58.662 8.966 20.044 1.00 65.92 ? 96 ILE K N 1 +ATOM 19796 C CA . ILE K 1 96 ? 59.808 8.276 19.518 1.00 66.67 ? 96 ILE K CA 1 +ATOM 19797 C C . ILE K 1 96 ? 59.587 6.783 19.681 1.00 66.01 ? 96 ILE K C 1 +ATOM 19798 O O . ILE K 1 96 ? 59.635 6.047 18.701 1.00 82.93 ? 96 ILE K O 1 +ATOM 19799 C CB . ILE K 1 96 ? 61.125 8.681 20.225 1.00 81.14 ? 96 ILE K CB 1 +ATOM 19800 C CG1 . ILE K 1 96 ? 61.475 10.141 19.926 1.00 67.03 ? 96 ILE K CG1 1 +ATOM 19801 C CG2 . ILE K 1 96 ? 62.267 7.799 19.739 1.00 80.11 ? 96 ILE K CG2 1 +ATOM 19802 C CD1 . ILE K 1 96 ? 62.790 10.572 20.541 1.00 60.66 ? 96 ILE K CD1 1 +ATOM 19803 N N . ARG K 1 97 ? 59.402 6.324 20.916 1.00 68.21 ? 97 ARG K N 1 +ATOM 19804 C CA . ARG K 1 97 ? 59.341 4.875 21.190 1.00 88.27 ? 97 ARG K CA 1 +ATOM 19805 C C . ARG K 1 97 ? 58.182 4.232 20.427 1.00 99.78 ? 97 ARG K C 1 +ATOM 19806 O O . ARG K 1 97 ? 58.249 3.053 20.039 1.00 81.96 ? 97 ARG K O 1 +ATOM 19807 C CB . ARG K 1 97 ? 59.190 4.598 22.692 1.00 88.80 ? 97 ARG K CB 1 +ATOM 19808 C CG . ARG K 1 97 ? 60.449 4.105 23.378 1.00 87.88 ? 97 ARG K CG 1 +ATOM 19809 C CD . ARG K 1 97 ? 60.195 3.805 24.849 1.00 100.38 ? 97 ARG K CD 1 +ATOM 19810 N NE . ARG K 1 97 ? 60.221 5.021 25.676 1.00 115.22 ? 97 ARG K NE 1 +ATOM 19811 C CZ . ARG K 1 97 ? 61.269 5.438 26.394 1.00 105.69 ? 97 ARG K CZ 1 +ATOM 19812 N NH1 . ARG K 1 97 ? 62.418 4.748 26.399 1.00 80.06 ? 97 ARG K NH1 1 +ATOM 19813 N NH2 . ARG K 1 97 ? 61.179 6.566 27.103 1.00 105.61 ? 97 ARG K NH2 1 +ATOM 19814 N N . ALA K 1 98 ? 57.123 5.007 20.208 1.00 85.27 ? 98 ALA K N 1 +ATOM 19815 C CA . ALA K 1 98 ? 55.981 4.509 19.468 1.00 90.15 ? 98 ALA K CA 1 +ATOM 19816 C C . ALA K 1 98 ? 56.276 4.449 17.977 1.00 82.52 ? 98 ALA K C 1 +ATOM 19817 O O . ALA K 1 98 ? 55.738 3.593 17.250 1.00 72.70 ? 98 ALA K O 1 +ATOM 19818 C CB . ALA K 1 98 ? 54.786 5.389 19.731 1.00 99.76 ? 98 ALA K CB 1 +ATOM 19819 N N . ALA K 1 99 ? 57.188 5.314 17.543 1.00 85.69 ? 99 ALA K N 1 +ATOM 19820 C CA . ALA K 1 99 ? 57.599 5.362 16.140 1.00 94.64 ? 99 ALA K CA 1 +ATOM 19821 C C . ALA K 1 99 ? 58.406 4.132 15.723 1.00 73.94 ? 99 ALA K C 1 +ATOM 19822 O O . ALA K 1 99 ? 58.136 3.514 14.700 1.00 82.17 ? 99 ALA K O 1 +ATOM 19823 C CB . ALA K 1 99 ? 58.402 6.635 15.867 1.00 121.03 ? 99 ALA K CB 1 +ATOM 19824 N N . GLN K 1 100 ? 59.406 3.800 16.512 1.00 66.94 ? 100 GLN K N 1 +ATOM 19825 C CA . GLN K 1 100 ? 60.458 2.918 16.043 1.00 92.50 ? 100 GLN K CA 1 +ATOM 19826 C C . GLN K 1 100 ? 60.397 1.537 16.653 1.00 97.03 ? 100 GLN K C 1 +ATOM 19827 O O . GLN K 1 100 ? 61.319 0.731 16.467 1.00 137.93 ? 100 GLN K O 1 +ATOM 19828 C CB . GLN K 1 100 ? 61.857 3.554 16.261 1.00 109.17 ? 100 GLN K CB 1 +ATOM 19829 C CG . GLN K 1 100 ? 62.059 4.260 17.592 1.00 102.44 ? 100 GLN K CG 1 +ATOM 19830 C CD . GLN K 1 100 ? 63.097 5.382 17.532 1.00 107.82 ? 100 GLN K CD 1 +ATOM 19831 O OE1 . GLN K 1 100 ? 62.971 6.366 16.765 1.00 66.25 ? 100 GLN K OE1 1 +ATOM 19832 N NE2 . GLN K 1 100 ? 64.117 5.244 18.369 1.00 95.53 ? 100 GLN K NE2 1 +ATOM 19833 N N . GLU K 1 101 ? 59.344 1.271 17.409 1.00 99.42 ? 101 GLU K N 1 +ATOM 19834 C CA . GLU K 1 101 ? 59.238 -0.007 18.119 1.00 113.64 ? 101 GLU K CA 1 +ATOM 19835 C C . GLU K 1 101 ? 59.056 -1.180 17.159 1.00 113.22 ? 101 GLU K C 1 +ATOM 19836 O O . GLU K 1 101 ? 59.365 -2.325 17.503 1.00 78.35 ? 101 GLU K O 1 +ATOM 19837 C CB . GLU K 1 101 ? 58.101 0.033 19.144 1.00 122.67 ? 101 GLU K CB 1 +ATOM 19838 C CG . GLU K 1 101 ? 56.764 0.509 18.589 1.00 134.94 ? 101 GLU K CG 1 +ATOM 19839 C CD . GLU K 1 101 ? 55.644 0.428 19.617 1.00 124.35 ? 101 GLU K CD 1 +ATOM 19840 O OE1 . GLU K 1 101 ? 55.959 0.363 20.822 1.00 122.62 ? 101 GLU K OE1 1 +ATOM 19841 O OE2 . GLU K 1 101 ? 54.454 0.497 19.229 1.00 103.67 ? 101 GLU K OE2 1 +ATOM 19842 N N . ASN K 1 102 ? 58.560 -0.904 15.956 1.00 114.30 ? 102 ASN K N 1 +ATOM 19843 C CA . ASN K 1 102 ? 58.296 -1.976 14.993 1.00 141.57 ? 102 ASN K CA 1 +ATOM 19844 C C . ASN K 1 102 ? 59.465 -2.257 14.047 1.00 172.07 ? 102 ASN K C 1 +ATOM 19845 O O . ASN K 1 102 ? 59.370 -3.118 13.181 1.00 160.05 ? 102 ASN K O 1 +ATOM 19846 C CB . ASN K 1 102 ? 57.043 -1.648 14.189 1.00 142.70 ? 102 ASN K CB 1 +ATOM 19847 C CG . ASN K 1 102 ? 55.796 -1.773 15.013 1.00 134.19 ? 102 ASN K CG 1 +ATOM 19848 O OD1 . ASN K 1 102 ? 55.300 -2.882 15.258 1.00 116.07 ? 102 ASN K OD1 1 +ATOM 19849 N ND2 . ASN K 1 102 ? 55.304 -0.631 15.503 1.00 133.91 ? 102 ASN K ND2 1 +ATOM 19850 N N . GLY K 1 103 ? 60.532 -1.472 14.157 1.00 180.28 ? 103 GLY K N 1 +ATOM 19851 C CA . GLY K 1 103 ? 61.678 -1.611 13.250 1.00 150.01 ? 103 GLY K CA 1 +ATOM 19852 C C . GLY K 1 103 ? 61.379 -1.396 11.772 1.00 125.44 ? 103 GLY K C 1 +ATOM 19853 O O . GLY K 1 103 ? 61.928 -2.069 10.906 1.00 145.40 ? 103 GLY K O 1 +ATOM 19854 N N . THR K 1 104 ? 60.442 -0.505 11.486 1.00 145.08 ? 104 THR K N 1 +ATOM 19855 C CA . THR K 1 104 ? 60.199 -0.088 10.121 1.00 150.87 ? 104 THR K CA 1 +ATOM 19856 C C . THR K 1 104 ? 60.856 1.250 9.896 1.00 137.37 ? 104 THR K C 1 +ATOM 19857 O O . THR K 1 104 ? 61.253 1.544 8.783 1.00 114.65 ? 104 THR K O 1 +ATOM 19858 C CB . THR K 1 104 ? 58.685 -0.004 9.773 1.00 165.42 ? 104 THR K CB 1 +ATOM 19859 O OG1 . THR K 1 104 ? 58.035 1.006 10.556 1.00 128.25 ? 104 THR K OG1 1 +ATOM 19860 C CG2 . THR K 1 104 ? 57.995 -1.358 10.001 1.00 149.11 ? 104 THR K CG2 1 +ATOM 19861 N N . VAL K 1 105 ? 61.008 2.043 10.955 1.00 160.34 ? 105 VAL K N 1 +ATOM 19862 C CA . VAL K 1 105 ? 61.500 3.419 10.795 1.00 190.14 ? 105 VAL K CA 1 +ATOM 19863 C C . VAL K 1 105 ? 62.886 3.432 10.144 1.00 201.38 ? 105 VAL K C 1 +ATOM 19864 O O . VAL K 1 105 ? 63.744 2.575 10.441 1.00 132.12 ? 105 VAL K O 1 +ATOM 19865 C CB . VAL K 1 105 ? 61.487 4.240 12.119 1.00 190.21 ? 105 VAL K CB 1 +ATOM 19866 C CG1 . VAL K 1 105 ? 62.641 5.245 12.183 1.00 176.51 ? 105 VAL K CG1 1 +ATOM 19867 C CG2 . VAL K 1 105 ? 60.157 4.970 12.283 1.00 168.26 ? 105 VAL K CG2 1 +ATOM 19868 N N . ALA K 1 106 ? 63.066 4.402 9.240 1.00 187.14 ? 106 ALA K N 1 +ATOM 19869 C CA . ALA K 1 106 ? 64.241 4.492 8.382 1.00 174.51 ? 106 ALA K CA 1 +ATOM 19870 C C . ALA K 1 106 ? 65.509 4.684 9.209 1.00 194.14 ? 106 ALA K C 1 +ATOM 19871 O O . ALA K 1 106 ? 65.541 5.501 10.135 1.00 291.16 ? 106 ALA K O 1 +ATOM 19872 C CB . ALA K 1 106 ? 64.076 5.636 7.395 1.00 148.47 ? 106 ALA K CB 1 +ATOM 19873 N N . ILE K 1 107 ? 66.541 3.909 8.886 1.00 163.48 ? 107 ILE K N 1 +ATOM 19874 C CA . ILE K 1 107 ? 67.771 3.867 9.682 1.00 148.64 ? 107 ILE K CA 1 +ATOM 19875 C C . ILE K 1 107 ? 68.442 5.253 9.816 1.00 127.28 ? 107 ILE K C 1 +ATOM 19876 O O . ILE K 1 107 ? 69.094 5.551 10.820 1.00 108.47 ? 107 ILE K O 1 +ATOM 19877 C CB . ILE K 1 107 ? 68.760 2.829 9.090 1.00 148.30 ? 107 ILE K CB 1 +ATOM 19878 C CG1 . ILE K 1 107 ? 69.912 2.549 10.062 1.00 150.28 ? 107 ILE K CG1 1 +ATOM 19879 C CG2 . ILE K 1 107 ? 69.299 3.296 7.740 1.00 144.22 ? 107 ILE K CG2 1 +ATOM 19880 C CD1 . ILE K 1 107 ? 69.480 2.056 11.432 1.00 137.32 ? 107 ILE K CD1 1 +ATOM 19881 N N . ASN K 1 108 ? 68.272 6.098 8.801 1.00 142.37 ? 108 ASN K N 1 +ATOM 19882 C CA . ASN K 1 108 ? 68.778 7.482 8.825 1.00 145.64 ? 108 ASN K CA 1 +ATOM 19883 C C . ASN K 1 108 ? 67.975 8.340 9.791 1.00 143.25 ? 108 ASN K C 1 +ATOM 19884 O O . ASN K 1 108 ? 68.507 9.233 10.445 1.00 138.83 ? 108 ASN K O 1 +ATOM 19885 C CB . ASN K 1 108 ? 68.692 8.118 7.433 1.00 153.56 ? 108 ASN K CB 1 +ATOM 19886 C CG . ASN K 1 108 ? 68.850 7.103 6.315 1.00 180.11 ? 108 ASN K CG 1 +ATOM 19887 O OD1 . ASN K 1 108 ? 69.966 6.792 5.899 1.00 196.09 ? 108 ASN K OD1 1 +ATOM 19888 N ND2 . ASN K 1 108 ? 67.728 6.571 5.829 1.00 169.36 ? 108 ASN K ND2 1 +ATOM 19889 N N . ASN K 1 109 ? 66.685 8.042 9.877 1.00 132.49 ? 109 ASN K N 1 +ATOM 19890 C CA . ASN K 1 109 ? 65.751 8.830 10.667 1.00 130.96 ? 109 ASN K CA 1 +ATOM 19891 C C . ASN K 1 109 ? 65.679 8.392 12.131 1.00 126.11 ? 109 ASN K C 1 +ATOM 19892 O O . ASN K 1 109 ? 65.189 9.135 12.985 1.00 151.81 ? 109 ASN K O 1 +ATOM 19893 C CB . ASN K 1 109 ? 64.357 8.752 10.036 1.00 140.89 ? 109 ASN K CB 1 +ATOM 19894 C CG . ASN K 1 109 ? 63.874 10.100 9.544 1.00 145.07 ? 109 ASN K CG 1 +ATOM 19895 O OD1 . ASN K 1 109 ? 62.912 10.651 10.071 1.00 139.08 ? 109 ASN K OD1 1 +ATOM 19896 N ND2 . ASN K 1 109 ? 64.568 10.658 8.557 1.00 147.45 ? 109 ASN K ND2 1 +ATOM 19897 N N . ARG K 1 110 ? 66.180 7.187 12.410 1.00 103.90 ? 110 ARG K N 1 +ATOM 19898 C CA . ARG K 1 110 ? 66.068 6.543 13.731 1.00 88.68 ? 110 ARG K CA 1 +ATOM 19899 C C . ARG K 1 110 ? 66.657 7.414 14.833 1.00 100.70 ? 110 ARG K C 1 +ATOM 19900 O O . ARG K 1 110 ? 67.764 7.970 14.678 1.00 107.61 ? 110 ARG K O 1 +ATOM 19901 C CB . ARG K 1 110 ? 66.823 5.202 13.704 1.00 95.75 ? 110 ARG K CB 1 +ATOM 19902 C CG . ARG K 1 110 ? 66.371 4.191 14.743 1.00 104.81 ? 110 ARG K CG 1 +ATOM 19903 C CD . ARG K 1 110 ? 66.469 2.763 14.228 1.00 110.36 ? 110 ARG K CD 1 +ATOM 19904 N NE . ARG K 1 110 ? 67.791 2.169 14.478 1.00 114.80 ? 110 ARG K NE 1 +ATOM 19905 C CZ . ARG K 1 110 ? 68.016 1.063 15.205 1.00 126.72 ? 110 ARG K CZ 1 +ATOM 19906 N NH1 . ARG K 1 110 ? 67.010 0.392 15.772 1.00 119.03 ? 110 ARG K NH1 1 +ATOM 19907 N NH2 . ARG K 1 110 ? 69.257 0.606 15.354 1.00 118.13 ? 110 ARG K NH2 1 +ATOM 19908 N N . ILE K 1 111 ? 65.935 7.551 15.947 1.00 105.80 ? 111 ILE K N 1 +ATOM 19909 C CA . ILE K 1 111 ? 66.479 8.266 17.122 1.00 115.66 ? 111 ILE K CA 1 +ATOM 19910 C C . ILE K 1 111 ? 66.802 7.297 18.253 1.00 118.92 ? 111 ILE K C 1 +ATOM 19911 O O . ILE K 1 111 ? 65.901 6.667 18.760 1.00 102.88 ? 111 ILE K O 1 +ATOM 19912 C CB . ILE K 1 111 ? 65.503 9.324 17.661 1.00 93.11 ? 111 ILE K CB 1 +ATOM 19913 C CG1 . ILE K 1 111 ? 65.293 10.407 16.597 1.00 97.95 ? 111 ILE K CG1 1 +ATOM 19914 C CG2 . ILE K 1 111 ? 66.057 9.948 18.934 1.00 90.44 ? 111 ILE K CG2 1 +ATOM 19915 C CD1 . ILE K 1 111 ? 64.150 11.348 16.880 1.00 95.51 ? 111 ILE K CD1 1 +ATOM 19916 N N . PRO K 1 112 ? 68.091 7.187 18.655 1.00 109.96 ? 112 PRO K N 1 +ATOM 19917 C CA . PRO K 1 112 ? 68.484 6.214 19.672 1.00 88.93 ? 112 PRO K CA 1 +ATOM 19918 C C . PRO K 1 112 ? 68.212 6.772 21.058 1.00 106.00 ? 112 PRO K C 1 +ATOM 19919 O O . PRO K 1 112 ? 68.564 7.944 21.329 1.00 105.11 ? 112 PRO K O 1 +ATOM 19920 C CB . PRO K 1 112 ? 69.977 6.057 19.444 1.00 88.47 ? 112 PRO K CB 1 +ATOM 19921 C CG . PRO K 1 112 ? 70.413 7.392 18.918 1.00 109.51 ? 112 PRO K CG 1 +ATOM 19922 C CD . PRO K 1 112 ? 69.236 8.002 18.199 1.00 117.23 ? 112 PRO K CD 1 +ATOM 19923 N N . LEU K 1 113 ? 67.512 5.984 21.885 1.00 116.37 ? 113 LEU K N 1 +ATOM 19924 C CA . LEU K 1 113 ? 66.992 6.462 23.178 1.00 101.93 ? 113 LEU K CA 1 +ATOM 19925 C C . LEU K 1 113 ? 67.678 5.837 24.349 1.00 91.34 ? 113 LEU K C 1 +ATOM 19926 O O . LEU K 1 113 ? 68.051 4.650 24.348 1.00 65.58 ? 113 LEU K O 1 +ATOM 19927 C CB . LEU K 1 113 ? 65.512 6.198 23.340 1.00 105.22 ? 113 LEU K CB 1 +ATOM 19928 C CG . LEU K 1 113 ? 64.584 7.272 22.777 1.00 119.93 ? 113 LEU K CG 1 +ATOM 19929 C CD1 . LEU K 1 113 ? 63.174 6.864 23.125 1.00 116.88 ? 113 LEU K CD1 1 +ATOM 19930 C CD2 . LEU K 1 113 ? 64.877 8.672 23.298 1.00 105.37 ? 113 LEU K CD2 1 +ATOM 19931 N N . GLN K 1 114 ? 67.959 6.711 25.301 1.00 100.60 ? 114 GLN K N 1 +ATOM 19932 C CA . GLN K 1 114 ? 68.921 6.442 26.345 1.00 115.12 ? 114 GLN K CA 1 +ATOM 19933 C C . GLN K 1 114 ? 68.300 7.062 27.545 1.00 93.67 ? 114 GLN K C 1 +ATOM 19934 O O . GLN K 1 114 ? 67.573 8.053 27.420 1.00 92.11 ? 114 GLN K O 1 +ATOM 19935 C CB . GLN K 1 114 ? 70.282 7.098 26.049 1.00 127.32 ? 114 GLN K CB 1 +ATOM 19936 C CG . GLN K 1 114 ? 71.494 6.336 26.593 1.00 120.64 ? 114 GLN K CG 1 +ATOM 19937 C CD . GLN K 1 114 ? 72.720 7.247 26.748 1.00 150.35 ? 114 GLN K CD 1 +ATOM 19938 O OE1 . GLN K 1 114 ? 72.807 8.279 26.083 1.00 144.05 ? 114 GLN K OE1 1 +ATOM 19939 N NE2 . GLN K 1 114 ? 73.590 6.937 27.710 1.00 143.63 ? 114 GLN K NE2 1 +ATOM 19940 N N . SER K 1 115 ? 68.520 6.430 28.690 1.00 88.73 ? 115 SER K N 1 +ATOM 19941 C CA . SER K 1 115 ? 67.861 6.831 29.919 1.00 106.78 ? 115 SER K CA 1 +ATOM 19942 C C . SER K 1 115 ? 68.173 8.293 30.209 1.00 97.91 ? 115 SER K C 1 +ATOM 19943 O O . SER K 1 115 ? 69.200 8.822 29.718 1.00 94.90 ? 115 SER K O 1 +ATOM 19944 C CB . SER K 1 115 ? 68.322 5.954 31.083 1.00 120.36 ? 115 SER K CB 1 +ATOM 19945 O OG . SER K 1 115 ? 69.752 5.916 31.168 1.00 120.57 ? 115 SER K OG 1 +ATOM 19946 N N . LEU K 1 116 ? 67.290 8.961 30.963 1.00 72.89 ? 116 LEU K N 1 +ATOM 19947 C CA . LEU K 1 116 ? 67.414 10.405 31.065 1.00 77.85 ? 116 LEU K CA 1 +ATOM 19948 C C . LEU K 1 116 ? 68.605 10.690 31.968 1.00 95.89 ? 116 LEU K C 1 +ATOM 19949 O O . LEU K 1 116 ? 68.707 10.095 33.031 1.00 70.52 ? 116 LEU K O 1 +ATOM 19950 C CB . LEU K 1 116 ? 66.181 11.051 31.636 1.00 63.38 ? 116 LEU K CB 1 +ATOM 19951 C CG . LEU K 1 116 ? 64.936 10.998 30.784 1.00 62.80 ? 116 LEU K CG 1 +ATOM 19952 C CD1 . LEU K 1 116 ? 64.077 9.763 31.179 1.00 77.09 ? 116 LEU K CD1 1 +ATOM 19953 C CD2 . LEU K 1 116 ? 64.155 12.288 30.947 1.00 44.75 ? 116 LEU K CD2 1 +ATOM 19954 N N . THR K 1 117 ? 69.563 11.481 31.465 1.00 114.69 ? 117 THR K N 1 +ATOM 19955 C CA . THR K 1 117 ? 70.796 11.804 32.195 1.00 93.43 ? 117 THR K CA 1 +ATOM 19956 C C . THR K 1 117 ? 70.405 12.417 33.498 1.00 98.04 ? 117 THR K C 1 +ATOM 19957 O O . THR K 1 117 ? 69.491 13.247 33.530 1.00 113.14 ? 117 THR K O 1 +ATOM 19958 C CB . THR K 1 117 ? 71.654 12.834 31.463 1.00 81.40 ? 117 THR K CB 1 +ATOM 19959 O OG1 . THR K 1 117 ? 71.932 12.372 30.141 1.00 98.90 ? 117 THR K OG1 1 +ATOM 19960 C CG2 . THR K 1 117 ? 72.959 13.048 32.199 1.00 92.79 ? 117 THR K CG2 1 +ATOM 19961 N N . ALA K 1 118 ? 71.026 11.946 34.573 1.00 100.86 ? 118 ALA K N 1 +ATOM 19962 C CA . ALA K 1 118 ? 70.552 12.256 35.912 1.00 112.78 ? 118 ALA K CA 1 +ATOM 19963 C C . ALA K 1 118 ? 71.573 13.092 36.658 1.00 96.01 ? 118 ALA K C 1 +ATOM 19964 O O . ALA K 1 118 ? 72.757 12.787 36.652 1.00 60.58 ? 118 ALA K O 1 +ATOM 19965 C CB . ALA K 1 118 ? 70.236 10.985 36.698 1.00 116.90 ? 118 ALA K CB 1 +ATOM 19966 N N . ALA K 1 119 ? 71.050 14.051 37.421 1.00 82.48 ? 119 ALA K N 1 +ATOM 19967 C CA . ALA K 1 119 ? 71.860 15.025 38.147 1.00 66.08 ? 119 ALA K CA 1 +ATOM 19968 C C . ALA K 1 119 ? 72.294 14.528 39.494 1.00 67.41 ? 119 ALA K C 1 +ATOM 19969 O O . ALA K 1 119 ? 71.595 13.686 40.116 1.00 85.71 ? 119 ALA K O 1 +ATOM 19970 C CB . ALA K 1 119 ? 71.065 16.307 38.310 1.00 73.27 ? 119 ALA K CB 1 +ATOM 19971 N N . ASN K 1 120 ? 73.389 15.085 40.007 1.00 92.12 ? 120 ASN K N 1 +ATOM 19972 C CA . ASN K 1 120 ? 73.797 14.766 41.387 1.00 124.44 ? 120 ASN K CA 1 +ATOM 19973 C C . ASN K 1 120 ? 73.409 15.826 42.416 1.00 85.42 ? 120 ASN K C 1 +ATOM 19974 O O . ASN K 1 120 ? 72.918 15.518 43.499 1.00 81.14 ? 120 ASN K O 1 +ATOM 19975 C CB . ASN K 1 120 ? 75.293 14.519 41.509 1.00 128.43 ? 120 ASN K CB 1 +ATOM 19976 C CG . ASN K 1 120 ? 75.683 14.076 42.921 1.00 139.98 ? 120 ASN K CG 1 +ATOM 19977 O OD1 . ASN K 1 120 ? 76.704 14.532 43.443 1.00 170.20 ? 120 ASN K OD1 1 +ATOM 19978 N ND2 . ASN K 1 120 ? 74.846 13.222 43.569 1.00 101.24 ? 120 ASN K ND2 1 +ATOM 19979 N N . ILE K 1 121 ? 73.648 17.068 42.074 1.00 56.39 ? 121 ILE K N 1 +ATOM 19980 C CA . ILE K 1 121 ? 73.186 18.134 42.908 1.00 49.06 ? 121 ILE K CA 1 +ATOM 19981 C C . ILE K 1 121 ? 72.098 18.805 42.147 1.00 43.20 ? 121 ILE K C 1 +ATOM 19982 O O . ILE K 1 121 ? 72.163 18.964 40.916 1.00 68.59 ? 121 ILE K O 1 +ATOM 19983 C CB . ILE K 1 121 ? 74.329 19.134 43.291 1.00 63.81 ? 121 ILE K CB 1 +ATOM 19984 C CG1 . ILE K 1 121 ? 74.790 20.011 42.109 1.00 55.00 ? 121 ILE K CG1 1 +ATOM 19985 C CG2 . ILE K 1 121 ? 75.513 18.380 43.885 1.00 76.56 ? 121 ILE K CG2 1 +ATOM 19986 C CD1 . ILE K 1 121 ? 74.405 21.455 42.256 1.00 50.88 ? 121 ILE K CD1 1 +ATOM 19987 N N . MET K 1 122 ? 71.112 19.275 42.857 1.00 38.20 ? 122 MET K N 1 +ATOM 19988 C CA . MET K 1 122 ? 70.151 20.157 42.224 1.00 53.43 ? 122 MET K CA 1 +ATOM 19989 C C . MET K 1 122 ? 70.070 21.440 43.039 1.00 49.74 ? 122 MET K C 1 +ATOM 19990 O O . MET K 1 122 ? 70.268 21.444 44.253 1.00 57.69 ? 122 MET K O 1 +ATOM 19991 C CB . MET K 1 122 ? 68.770 19.483 42.059 1.00 65.09 ? 122 MET K CB 1 +ATOM 19992 C CG . MET K 1 122 ? 68.151 18.968 43.347 1.00 88.19 ? 122 MET K CG 1 +ATOM 19993 S SD . MET K 1 122 ? 66.371 18.903 43.206 1.00 68.42 ? 122 MET K SD 1 +ATOM 19994 C CE . MET K 1 122 ? 65.888 19.577 44.830 1.00 104.17 ? 122 MET K CE 1 +ATOM 19995 N N . VAL K 1 123 ? 69.866 22.548 42.353 1.00 49.90 ? 123 VAL K N 1 +ATOM 19996 C CA . VAL K 1 123 ? 69.901 23.845 43.000 1.00 58.68 ? 123 VAL K CA 1 +ATOM 19997 C C . VAL K 1 123 ? 68.566 24.462 42.794 1.00 54.10 ? 123 VAL K C 1 +ATOM 19998 O O . VAL K 1 123 ? 68.138 24.662 41.664 1.00 52.98 ? 123 VAL K O 1 +ATOM 19999 C CB . VAL K 1 123 ? 71.034 24.803 42.467 1.00 63.91 ? 123 VAL K CB 1 +ATOM 20000 C CG1 . VAL K 1 123 ? 71.201 24.678 40.965 1.00 74.33 ? 123 VAL K CG1 1 +ATOM 20001 C CG2 . VAL K 1 123 ? 70.773 26.256 42.873 1.00 59.13 ? 123 VAL K CG2 1 +ATOM 20002 N N . GLU K 1 124 ? 67.949 24.870 43.892 1.00 68.13 ? 124 GLU K N 1 +ATOM 20003 C CA . GLU K 1 124 ? 66.741 25.700 43.806 1.00 83.81 ? 124 GLU K CA 1 +ATOM 20004 C C . GLU K 1 124 ? 66.892 26.978 44.600 1.00 57.57 ? 124 GLU K C 1 +ATOM 20005 O O . GLU K 1 124 ? 67.799 27.114 45.409 1.00 61.25 ? 124 GLU K O 1 +ATOM 20006 C CB . GLU K 1 124 ? 65.508 24.903 44.260 1.00 95.43 ? 124 GLU K CB 1 +ATOM 20007 C CG . GLU K 1 124 ? 65.782 23.830 45.296 1.00 91.85 ? 124 GLU K CG 1 +ATOM 20008 C CD . GLU K 1 124 ? 64.635 22.855 45.372 1.00 85.65 ? 124 GLU K CD 1 +ATOM 20009 O OE1 . GLU K 1 124 ? 64.065 22.503 44.313 1.00 111.47 ? 124 GLU K OE1 1 +ATOM 20010 O OE2 . GLU K 1 124 ? 64.360 22.361 46.473 1.00 95.81 ? 124 GLU K OE2 1 +ATOM 20011 N N . GLY K 1 125 ? 65.920 27.848 44.452 1.00 48.19 ? 125 GLY K N 1 +ATOM 20012 C CA . GLY K 1 125 ? 65.945 29.095 45.157 1.00 51.56 ? 125 GLY K CA 1 +ATOM 20013 C C . GLY K 1 125 ? 64.649 29.846 45.028 1.00 60.27 ? 125 GLY K C 1 +ATOM 20014 O O . GLY K 1 125 ? 63.607 29.292 44.629 1.00 83.90 ? 125 GLY K O 1 +ATOM 20015 N N . SER K 1 126 ? 64.721 31.149 45.237 1.00 62.34 ? 126 SER K N 1 +ATOM 20016 C CA . SER K 1 126 ? 63.518 31.953 45.188 1.00 74.30 ? 126 SER K CA 1 +ATOM 20017 C C . SER K 1 126 ? 63.929 33.394 44.966 1.00 66.86 ? 126 SER K C 1 +ATOM 20018 O O . SER K 1 126 ? 64.919 33.832 45.522 1.00 43.83 ? 126 SER K O 1 +ATOM 20019 C CB . SER K 1 126 ? 62.714 31.790 46.505 1.00 85.69 ? 126 SER K CB 1 +ATOM 20020 O OG . SER K 1 126 ? 62.867 30.492 47.097 1.00 62.84 ? 126 SER K OG 1 +ATOM 20021 N N . ILE K 1 127 ? 63.067 34.157 44.313 1.00 76.01 ? 127 ILE K N 1 +ATOM 20022 C CA . ILE K 1 127 ? 63.130 35.591 44.465 1.00 92.61 ? 127 ILE K CA 1 +ATOM 20023 C C . ILE K 1 127 ? 62.523 35.979 45.831 1.00 100.98 ? 127 ILE K C 1 +ATOM 20024 O O . ILE K 1 127 ? 61.316 36.070 45.986 1.00 130.65 ? 127 ILE K O 1 +ATOM 20025 C CB . ILE K 1 127 ? 62.419 36.333 43.317 1.00 90.38 ? 127 ILE K CB 1 +ATOM 20026 C CG1 . ILE K 1 127 ? 63.121 36.007 41.995 1.00 92.54 ? 127 ILE K CG1 1 +ATOM 20027 C CG2 . ILE K 1 127 ? 62.413 37.848 43.570 1.00 79.64 ? 127 ILE K CG2 1 +ATOM 20028 C CD1 . ILE K 1 127 ? 62.194 36.015 40.792 1.00 90.11 ? 127 ILE K CD1 1 +ATOM 20029 N N . ILE K 1 128 ? 63.398 36.247 46.803 1.00 81.26 ? 128 ILE K N 1 +ATOM 20030 C CA . ILE K 1 128 ? 63.017 36.710 48.163 1.00 52.00 ? 128 ILE K CA 1 +ATOM 20031 C C . ILE K 1 128 ? 62.990 38.236 48.164 1.00 64.19 ? 128 ILE K C 1 +ATOM 20032 O O . ILE K 1 128 ? 64.042 38.917 48.037 1.00 116.28 ? 128 ILE K O 1 +ATOM 20033 C CB . ILE K 1 128 ? 63.985 36.166 49.193 1.00 37.41 ? 128 ILE K CB 1 +ATOM 20034 C CG1 . ILE K 1 128 ? 65.438 36.509 48.824 1.00 44.49 ? 128 ILE K CG1 1 +ATOM 20035 C CG2 . ILE K 1 128 ? 63.951 34.657 49.167 1.00 36.45 ? 128 ILE K CG2 1 +ATOM 20036 C CD1 . ILE K 1 128 ? 66.391 36.505 50.014 1.00 42.96 ? 128 ILE K CD1 1 +ATOM 20037 N N . GLY K 1 129 ? 61.799 38.768 47.935 1.00 65.61 ? 129 GLY K N 1 +ATOM 20038 C CA . GLY K 1 129 ? 61.596 40.180 48.107 1.00 73.39 ? 129 GLY K CA 1 +ATOM 20039 C C . GLY K 1 129 ? 61.813 41.051 46.874 1.00 74.27 ? 129 GLY K C 1 +ATOM 20040 O O . GLY K 1 129 ? 62.895 41.034 46.231 1.00 73.13 ? 129 GLY K O 1 +ATOM 20041 N N . TYR K 1 130 ? 60.909 42.019 46.753 1.00 76.08 ? 130 TYR K N 1 +ATOM 20042 C CA . TYR K 1 130 ? 61.180 43.249 46.034 1.00 94.59 ? 130 TYR K CA 1 +ATOM 20043 C C . TYR K 1 130 ? 60.555 44.353 46.846 1.00 101.17 ? 130 TYR K C 1 +ATOM 20044 O O . TYR K 1 130 ? 59.343 44.438 46.942 1.00 96.01 ? 130 TYR K O 1 +ATOM 20045 C CB . TYR K 1 130 ? 60.554 43.150 44.651 1.00 113.42 ? 130 TYR K CB 1 +ATOM 20046 C CG . TYR K 1 130 ? 60.619 44.402 43.779 1.00 126.85 ? 130 TYR K CG 1 +ATOM 20047 C CD1 . TYR K 1 130 ? 59.760 45.475 43.999 1.00 127.64 ? 130 TYR K CD1 1 +ATOM 20048 C CD2 . TYR K 1 130 ? 61.440 44.441 42.648 1.00 114.61 ? 130 TYR K CD2 1 +ATOM 20049 C CE1 . TYR K 1 130 ? 59.802 46.604 43.197 1.00 104.28 ? 130 TYR K CE1 1 +ATOM 20050 C CE2 . TYR K 1 130 ? 61.471 45.554 41.830 1.00 99.84 ? 130 TYR K CE2 1 +ATOM 20051 C CZ . TYR K 1 130 ? 60.674 46.639 42.128 1.00 89.81 ? 130 TYR K CZ 1 +ATOM 20052 O OH . TYR K 1 130 ? 60.717 47.714 41.303 1.00 78.87 ? 130 TYR K OH 1 +ATOM 20053 N N . GLU K 1 131 ? 61.378 45.195 47.467 1.00 114.22 ? 131 GLU K N 1 +ATOM 20054 C CA . GLU K 1 131 ? 60.869 46.421 48.090 1.00 122.44 ? 131 GLU K CA 1 +ATOM 20055 C C . GLU K 1 131 ? 61.045 47.604 47.144 1.00 94.31 ? 131 GLU K C 1 +ATOM 20056 O O . GLU K 1 131 ? 61.967 47.607 46.319 1.00 85.54 ? 131 GLU K O 1 +ATOM 20057 C CB . GLU K 1 131 ? 61.601 46.668 49.395 1.00 157.39 ? 131 GLU K CB 1 +ATOM 20058 C CG . GLU K 1 131 ? 61.019 47.766 50.274 1.00 155.53 ? 131 GLU K CG 1 +ATOM 20059 C CD . GLU K 1 131 ? 59.925 47.286 51.215 1.00 138.81 ? 131 GLU K CD 1 +ATOM 20060 O OE1 . GLU K 1 131 ? 59.935 46.084 51.600 1.00 140.03 ? 131 GLU K OE1 1 +ATOM 20061 O OE2 . GLU K 1 131 ? 59.074 48.122 51.586 1.00 127.73 ? 131 GLU K OE2 1 +ATOM 20062 N N . SER K 1 132 ? 60.104 48.545 47.177 1.00 80.69 ? 132 SER K N 1 +ATOM 20063 C CA . SER K 1 132 ? 60.059 49.599 46.160 1.00 91.45 ? 132 SER K CA 1 +ATOM 20064 C C . SER K 1 132 ? 60.233 50.992 46.760 1.00 96.41 ? 132 SER K C 1 +ATOM 20065 O O . SER K 1 132 ? 59.690 51.276 47.838 1.00 131.03 ? 132 SER K O 1 +ATOM 20066 C CB . SER K 1 132 ? 58.750 49.521 45.375 1.00 93.96 ? 132 SER K CB 1 +ATOM 20067 O OG . SER K 1 132 ? 57.925 50.642 45.639 1.00 103.09 ? 132 SER K OG 1 +ATOM 20068 N N . ASN K 1 133 ? 60.963 51.853 46.050 1.00 83.85 ? 133 ASN K N 1 +ATOM 20069 C CA . ASN K 1 133 ? 61.385 53.144 46.595 1.00 102.13 ? 133 ASN K CA 1 +ATOM 20070 C C . ASN K 1 133 ? 61.969 52.986 47.989 1.00 107.24 ? 133 ASN K C 1 +ATOM 20071 O O . ASN K 1 133 ? 61.523 53.622 48.953 1.00 102.02 ? 133 ASN K O 1 +ATOM 20072 C CB . ASN K 1 133 ? 60.233 54.147 46.639 1.00 107.30 ? 133 ASN K CB 1 +ATOM 20073 C CG . ASN K 1 133 ? 59.660 54.432 45.264 1.00 126.01 ? 133 ASN K CG 1 +ATOM 20074 O OD1 . ASN K 1 133 ? 60.351 54.341 44.242 1.00 109.94 ? 133 ASN K OD1 1 +ATOM 20075 N ND2 . ASN K 1 133 ? 58.373 54.743 45.233 1.00 134.60 ? 133 ASN K ND2 1 +ATOM 20076 N N . VAL K 1 134 ? 62.990 52.139 48.075 1.00 102.17 ? 134 VAL K N 1 +ATOM 20077 C CA . VAL K 1 134 ? 63.703 51.896 49.323 1.00 101.20 ? 134 VAL K CA 1 +ATOM 20078 C C . VAL K 1 134 ? 64.462 53.177 49.695 1.00 117.95 ? 134 VAL K C 1 +ATOM 20079 O O . VAL K 1 134 ? 64.539 53.549 50.868 1.00 115.14 ? 134 VAL K O 1 +ATOM 20080 C CB . VAL K 1 134 ? 64.681 50.714 49.177 1.00 100.16 ? 134 VAL K CB 1 +ATOM 20081 C CG1 . VAL K 1 134 ? 65.362 50.401 50.490 1.00 111.89 ? 134 VAL K CG1 1 +ATOM 20082 C CG2 . VAL K 1 134 ? 63.949 49.481 48.666 1.00 111.02 ? 134 VAL K CG2 1 +ATOM 20083 N N . LYS K 1 135 ? 64.948 53.889 48.678 1.00 132.38 ? 135 LYS K N 1 +ATOM 20084 C CA . LYS K 1 135 ? 65.342 55.290 48.847 1.00 115.74 ? 135 LYS K CA 1 +ATOM 20085 C C . LYS K 1 135 ? 64.820 56.152 47.712 1.00 117.65 ? 135 LYS K C 1 +ATOM 20086 O O . LYS K 1 135 ? 64.521 55.662 46.597 1.00 144.00 ? 135 LYS K O 1 +ATOM 20087 C CB . LYS K 1 135 ? 66.854 55.401 48.909 1.00 110.33 ? 135 LYS K CB 1 +ATOM 20088 C CG . LYS K 1 135 ? 67.453 54.673 50.095 1.00 118.58 ? 135 LYS K CG 1 +ATOM 20089 C CD . LYS K 1 135 ? 68.969 54.722 50.030 1.00 123.65 ? 135 LYS K CD 1 +ATOM 20090 C CE . LYS K 1 135 ? 69.610 54.002 51.197 1.00 123.36 ? 135 LYS K CE 1 +ATOM 20091 N NZ . LYS K 1 135 ? 71.009 54.469 51.393 1.00 100.30 ? 135 LYS K NZ 1 +ATOM 20092 N N . SER K 1 136 ? 64.751 57.450 47.979 1.00 104.88 ? 136 SER K N 1 +ATOM 20093 C CA . SER K 1 136 ? 64.332 58.406 46.963 1.00 115.17 ? 136 SER K CA 1 +ATOM 20094 C C . SER K 1 136 ? 64.740 59.823 47.323 1.00 128.65 ? 136 SER K C 1 +ATOM 20095 O O . SER K 1 136 ? 64.957 60.131 48.493 1.00 172.97 ? 136 SER K O 1 +ATOM 20096 C CB . SER K 1 136 ? 62.823 58.321 46.748 1.00 99.46 ? 136 SER K CB 1 +ATOM 20097 O OG . SER K 1 136 ? 62.201 59.582 46.920 1.00 99.27 ? 136 SER K OG 1 +ATOM 20098 N N . GLY K 1 137 ? 64.856 60.679 46.312 1.00 120.82 ? 137 GLY K N 1 +ATOM 20099 C CA . GLY K 1 137 ? 65.180 62.077 46.547 1.00 137.43 ? 137 GLY K CA 1 +ATOM 20100 C C . GLY K 1 137 ? 64.954 62.966 45.345 1.00 143.66 ? 137 GLY K C 1 +ATOM 20101 O O . GLY K 1 137 ? 64.596 62.498 44.267 1.00 159.67 ? 137 GLY K O 1 +ATOM 20102 N N . GLY K 1 138 ? 65.130 64.271 45.541 1.00 173.66 ? 138 GLY K N 1 +ATOM 20103 C CA . GLY K 1 138 ? 64.984 65.237 44.452 1.00 175.73 ? 138 GLY K CA 1 +ATOM 20104 C C . GLY K 1 138 ? 65.581 66.597 44.757 1.00 163.36 ? 138 GLY K C 1 +ATOM 20105 O O . GLY K 1 138 ? 65.577 67.037 45.908 1.00 177.15 ? 138 GLY K O 1 +ATOM 20106 N N . VAL K 1 139 ? 66.134 67.236 43.728 1.00 136.61 ? 139 VAL K N 1 +ATOM 20107 C CA . VAL K 1 139 ? 66.727 68.563 43.868 1.00 133.07 ? 139 VAL K CA 1 +ATOM 20108 C C . VAL K 1 139 ? 66.388 69.413 42.660 1.00 134.05 ? 139 VAL K C 1 +ATOM 20109 O O . VAL K 1 139 ? 66.638 69.012 41.521 1.00 155.04 ? 139 VAL K O 1 +ATOM 20110 C CB . VAL K 1 139 ? 68.262 68.506 43.993 1.00 125.15 ? 139 VAL K CB 1 +ATOM 20111 C CG1 . VAL K 1 139 ? 68.840 69.911 44.005 1.00 109.32 ? 139 VAL K CG1 1 +ATOM 20112 C CG2 . VAL K 1 139 ? 68.679 67.756 45.253 1.00 154.83 ? 139 VAL K CG2 1 +ATOM 20113 N N . GLY K 1 140 ? 65.834 70.598 42.907 1.00 143.61 ? 140 GLY K N 1 +ATOM 20114 C CA . GLY K 1 140 ? 65.435 71.509 41.829 1.00 157.51 ? 140 GLY K CA 1 +ATOM 20115 C C . GLY K 1 140 ? 65.531 72.988 42.168 1.00 148.53 ? 140 GLY K C 1 +ATOM 20116 O O . GLY K 1 140 ? 65.284 73.389 43.300 1.00 157.31 ? 140 GLY K O 1 +ATOM 20117 N N . ALA K 1 141 ? 65.876 73.798 41.172 1.00 143.34 ? 141 ALA K N 1 +ATOM 20118 C CA . ALA K 1 141 ? 65.998 75.237 41.355 1.00 132.79 ? 141 ALA K CA 1 +ATOM 20119 C C . ALA K 1 141 ? 65.560 76.021 40.109 1.00 147.16 ? 141 ALA K C 1 +ATOM 20120 O O . ALA K 1 141 ? 65.805 75.611 38.970 1.00 173.00 ? 141 ALA K O 1 +ATOM 20121 C CB . ALA K 1 141 ? 67.427 75.586 41.730 1.00 115.21 ? 141 ALA K CB 1 +ATOM 20122 N N . ARG K 1 142 ? 64.867 77.127 40.338 1.00 163.28 ? 142 ARG K N 1 +ATOM 20123 C CA . ARG K 1 142 ? 64.505 78.022 39.259 1.00 170.18 ? 142 ARG K CA 1 +ATOM 20124 C C . ARG K 1 142 ? 64.918 79.437 39.630 1.00 190.39 ? 142 ARG K C 1 +ATOM 20125 O O . ARG K 1 142 ? 64.884 79.819 40.800 1.00 189.13 ? 142 ARG K O 1 +ATOM 20126 C CB . ARG K 1 142 ? 63.005 77.951 38.961 1.00 182.22 ? 142 ARG K CB 1 +ATOM 20127 C CG . ARG K 1 142 ? 62.585 78.806 37.769 1.00 193.19 ? 142 ARG K CG 1 +ATOM 20128 C CD . ARG K 1 142 ? 61.582 78.110 36.862 1.00 189.16 ? 142 ARG K CD 1 +ATOM 20129 N NE . ARG K 1 142 ? 60.200 78.296 37.293 1.00 187.90 ? 142 ARG K NE 1 +ATOM 20130 C CZ . ARG K 1 142 ? 59.190 77.490 36.981 1.00 176.62 ? 142 ARG K CZ 1 +ATOM 20131 N NH1 . ARG K 1 142 ? 59.404 76.385 36.280 1.00 188.13 ? 142 ARG K NH1 1 +ATOM 20132 N NH2 . ARG K 1 142 ? 57.962 77.769 37.405 1.00 163.35 ? 142 ARG K NH2 1 +ATOM 20133 N N . TYR K 1 143 ? 65.352 80.195 38.626 1.00 206.13 ? 143 TYR K N 1 +ATOM 20134 C CA . TYR K 1 143 ? 65.949 81.515 38.842 1.00 195.59 ? 143 TYR K CA 1 +ATOM 20135 C C . TYR K 1 143 ? 65.333 82.570 37.918 1.00 166.86 ? 143 TYR K C 1 +ATOM 20136 O O . TYR K 1 143 ? 65.851 82.858 36.835 1.00 105.04 ? 143 TYR K O 1 +ATOM 20137 C CB . TYR K 1 143 ? 67.455 81.427 38.619 1.00 209.05 ? 143 TYR K CB 1 +ATOM 20138 C CG . TYR K 1 143 ? 68.235 82.649 38.976 1.00 206.29 ? 143 TYR K CG 1 +ATOM 20139 C CD1 . TYR K 1 143 ? 68.490 82.963 40.309 1.00 187.09 ? 143 TYR K CD1 1 +ATOM 20140 C CD2 . TYR K 1 143 ? 68.850 83.405 37.986 1.00 190.16 ? 143 TYR K CD2 1 +ATOM 20141 C CE1 . TYR K 1 143 ? 69.287 84.038 40.647 1.00 169.19 ? 143 TYR K CE1 1 +ATOM 20142 C CE2 . TYR K 1 143 ? 69.659 84.479 38.316 1.00 171.40 ? 143 TYR K CE2 1 +ATOM 20143 C CZ . TYR K 1 143 ? 69.868 84.793 39.645 1.00 163.93 ? 143 TYR K CZ 1 +ATOM 20144 O OH . TYR K 1 143 ? 70.654 85.870 39.976 1.00 169.76 ? 143 TYR K OH 1 +ATOM 20145 N N . GLY K 1 145 ? 63.741 82.880 35.709 1.00 105.70 ? 145 GLY K N 1 +ATOM 20146 C CA . GLY K 1 145 ? 63.181 82.386 34.455 1.00 124.62 ? 145 GLY K CA 1 +ATOM 20147 C C . GLY K 1 145 ? 63.637 80.989 34.034 1.00 136.55 ? 145 GLY K C 1 +ATOM 20148 O O . GLY K 1 145 ? 62.942 80.328 33.260 1.00 130.18 ? 145 GLY K O 1 +ATOM 20149 N N . ILE K 1 146 ? 64.813 80.560 34.490 1.00 152.03 ? 146 ILE K N 1 +ATOM 20150 C CA . ILE K 1 146 ? 65.441 79.319 34.007 1.00 154.09 ? 146 ILE K CA 1 +ATOM 20151 C C . ILE K 1 146 ? 65.472 78.319 35.161 1.00 179.62 ? 146 ILE K C 1 +ATOM 20152 O O . ILE K 1 146 ? 65.766 78.689 36.294 1.00 220.04 ? 146 ILE K O 1 +ATOM 20153 C CB . ILE K 1 146 ? 66.885 79.561 33.476 1.00 140.70 ? 146 ILE K CB 1 +ATOM 20154 C CG1 . ILE K 1 146 ? 66.963 80.879 32.681 1.00 124.51 ? 146 ILE K CG1 1 +ATOM 20155 C CG2 . ILE K 1 146 ? 67.348 78.393 32.612 1.00 104.72 ? 146 ILE K CG2 1 +ATOM 20156 C CD1 . ILE K 1 146 ? 67.459 82.059 33.489 1.00 107.00 ? 146 ILE K CD1 1 +ATOM 20157 N N . GLY K 1 147 ? 65.152 77.059 34.894 1.00 174.06 ? 147 GLY K N 1 +ATOM 20158 C CA . GLY K 1 147 ? 65.071 76.076 35.976 1.00 174.04 ? 147 GLY K CA 1 +ATOM 20159 C C . GLY K 1 147 ? 65.412 74.656 35.591 1.00 162.39 ? 147 GLY K C 1 +ATOM 20160 O O . GLY K 1 147 ? 65.283 74.261 34.443 1.00 177.71 ? 147 GLY K O 1 +ATOM 20161 N N . ALA K 1 148 ? 65.837 73.877 36.577 1.00 160.41 ? 148 ALA K N 1 +ATOM 20162 C CA . ALA K 1 148 ? 66.066 72.456 36.381 1.00 132.08 ? 148 ALA K CA 1 +ATOM 20163 C C . ALA K 1 148 ? 65.753 71.690 37.664 1.00 133.45 ? 148 ALA K C 1 +ATOM 20164 O O . ALA K 1 148 ? 65.577 72.276 38.739 1.00 166.74 ? 148 ALA K O 1 +ATOM 20165 C CB . ALA K 1 148 ? 67.495 72.199 35.914 1.00 95.94 ? 148 ALA K CB 1 +ATOM 20166 N N . ASP K 1 149 ? 65.635 70.378 37.532 1.00 145.98 ? 149 ASP K N 1 +ATOM 20167 C CA . ASP K 1 149 ? 65.429 69.511 38.684 1.00 154.50 ? 149 ASP K CA 1 +ATOM 20168 C C . ASP K 1 149 ? 65.732 68.057 38.327 1.00 158.15 ? 149 ASP K C 1 +ATOM 20169 O O . ASP K 1 149 ? 65.553 67.645 37.178 1.00 131.35 ? 149 ASP K O 1 +ATOM 20170 C CB . ASP K 1 149 ? 64.002 69.655 39.223 1.00 127.93 ? 149 ASP K CB 1 +ATOM 20171 C CG . ASP K 1 149 ? 63.017 68.860 38.445 1.00 129.89 ? 149 ASP K CG 1 +ATOM 20172 O OD1 . ASP K 1 149 ? 62.670 69.295 37.325 1.00 166.96 ? 149 ASP K OD1 1 +ATOM 20173 O OD2 . ASP K 1 149 ? 62.587 67.799 38.941 1.00 114.14 ? 149 ASP K OD2 1 +ATOM 20174 N N . THR K 1 150 ? 66.262 67.307 39.289 1.00 156.08 ? 150 THR K N 1 +ATOM 20175 C CA . THR K 1 150 ? 66.322 65.862 39.146 1.00 144.41 ? 150 THR K CA 1 +ATOM 20176 C C . THR K 1 150 ? 65.570 65.209 40.287 1.00 141.52 ? 150 THR K C 1 +ATOM 20177 O O . THR K 1 150 ? 65.383 65.803 41.354 1.00 123.83 ? 150 THR K O 1 +ATOM 20178 C CB . THR K 1 150 ? 67.765 65.318 39.111 1.00 121.44 ? 150 THR K CB 1 +ATOM 20179 O OG1 . THR K 1 150 ? 68.430 65.684 40.319 1.00 155.88 ? 150 THR K OG1 1 +ATOM 20180 C CG2 . THR K 1 150 ? 68.518 65.860 37.915 1.00 102.62 ? 150 THR K CG2 1 +ATOM 20181 N N . GLN K 1 151 ? 65.082 64.003 40.020 1.00 142.18 ? 151 GLN K N 1 +ATOM 20182 C CA . GLN K 1 151 ? 64.444 63.171 41.024 1.00 133.99 ? 151 GLN K CA 1 +ATOM 20183 C C . GLN K 1 151 ? 64.911 61.740 40.847 1.00 131.89 ? 151 GLN K C 1 +ATOM 20184 O O . GLN K 1 151 ? 65.157 61.316 39.728 1.00 187.56 ? 151 GLN K O 1 +ATOM 20185 C CB . GLN K 1 151 ? 62.936 63.236 40.857 1.00 104.20 ? 151 GLN K CB 1 +ATOM 20186 C CG . GLN K 1 151 ? 62.359 64.562 41.283 1.00 110.85 ? 151 GLN K CG 1 +ATOM 20187 C CD . GLN K 1 151 ? 61.023 64.823 40.641 1.00 139.17 ? 151 GLN K CD 1 +ATOM 20188 O OE1 . GLN K 1 151 ? 60.206 63.916 40.531 1.00 138.89 ? 151 GLN K OE1 1 +ATOM 20189 N NE2 . GLN K 1 151 ? 60.790 66.066 40.210 1.00 156.44 ? 151 GLN K NE2 1 +ATOM 20190 N N . TYR K 1 152 ? 65.125 61.025 41.943 1.00 109.81 ? 152 TYR K N 1 +ATOM 20191 C CA . TYR K 1 152 ? 65.592 59.655 41.826 1.00 96.54 ? 152 TYR K CA 1 +ATOM 20192 C C . TYR K 1 152 ? 64.871 58.766 42.791 1.00 107.55 ? 152 TYR K C 1 +ATOM 20193 O O . TYR K 1 152 ? 64.519 59.191 43.902 1.00 119.78 ? 152 TYR K O 1 +ATOM 20194 C CB . TYR K 1 152 ? 67.107 59.569 42.010 1.00 89.08 ? 152 TYR K CB 1 +ATOM 20195 C CG . TYR K 1 152 ? 67.588 59.037 43.340 1.00 90.29 ? 152 TYR K CG 1 +ATOM 20196 C CD1 . TYR K 1 152 ? 67.387 59.755 44.550 1.00 84.66 ? 152 TYR K CD1 1 +ATOM 20197 C CD2 . TYR K 1 152 ? 68.368 57.897 43.382 1.00 80.30 ? 152 TYR K CD2 1 +ATOM 20198 C CE1 . TYR K 1 152 ? 67.893 59.293 45.766 1.00 68.99 ? 152 TYR K CE1 1 +ATOM 20199 C CE2 . TYR K 1 152 ? 68.926 57.455 44.588 1.00 87.28 ? 152 TYR K CE2 1 +ATOM 20200 C CZ . TYR K 1 152 ? 68.697 58.157 45.774 1.00 76.22 ? 152 TYR K CZ 1 +ATOM 20201 O OH . TYR K 1 152 ? 69.234 57.673 46.938 1.00 56.57 ? 152 TYR K OH 1 +ATOM 20202 N N . GLN K 1 153 ? 64.641 57.529 42.369 1.00 104.48 ? 153 GLN K N 1 +ATOM 20203 C CA . GLN K 1 153 ? 64.159 56.502 43.284 1.00 113.28 ? 153 GLN K CA 1 +ATOM 20204 C C . GLN K 1 153 ? 64.924 55.200 43.083 1.00 113.48 ? 153 GLN K C 1 +ATOM 20205 O O . GLN K 1 153 ? 65.517 54.980 42.011 1.00 166.50 ? 153 GLN K O 1 +ATOM 20206 C CB . GLN K 1 153 ? 62.679 56.265 43.053 1.00 112.64 ? 153 GLN K CB 1 +ATOM 20207 C CG . GLN K 1 153 ? 61.775 57.455 43.390 1.00 129.00 ? 153 GLN K CG 1 +ATOM 20208 C CD . GLN K 1 153 ? 60.311 57.179 43.004 1.00 145.60 ? 153 GLN K CD 1 +ATOM 20209 O OE1 . GLN K 1 153 ? 60.026 56.296 42.187 1.00 148.24 ? 153 GLN K OE1 1 +ATOM 20210 N NE2 . GLN K 1 153 ? 59.386 57.932 43.591 1.00 157.96 ? 153 GLN K NE2 1 +ATOM 20211 N N . LEU K 1 154 ? 65.011 54.387 44.137 1.00 83.59 ? 154 LEU K N 1 +ATOM 20212 C CA . LEU K 1 154 ? 65.638 53.081 43.986 1.00 80.16 ? 154 LEU K CA 1 +ATOM 20213 C C . LEU K 1 154 ? 64.956 52.009 44.799 1.00 89.17 ? 154 LEU K C 1 +ATOM 20214 O O . LEU K 1 154 ? 64.520 52.245 45.938 1.00 97.42 ? 154 LEU K O 1 +ATOM 20215 C CB . LEU K 1 154 ? 67.132 53.127 44.307 1.00 75.08 ? 154 LEU K CB 1 +ATOM 20216 C CG . LEU K 1 154 ? 67.489 53.321 45.777 1.00 92.26 ? 154 LEU K CG 1 +ATOM 20217 C CD1 . LEU K 1 154 ? 67.759 51.986 46.449 1.00 97.98 ? 154 LEU K CD1 1 +ATOM 20218 C CD2 . LEU K 1 154 ? 68.698 54.235 45.898 1.00 116.09 ? 154 LEU K CD2 1 +ATOM 20219 N N . ASP K 1 155 ? 64.975 50.804 44.222 1.00 105.74 ? 155 ASP K N 1 +ATOM 20220 C CA . ASP K 1 155 ? 64.217 49.636 44.690 1.00 94.03 ? 155 ASP K CA 1 +ATOM 20221 C C . ASP K 1 155 ? 65.199 48.496 44.974 1.00 95.40 ? 155 ASP K C 1 +ATOM 20222 O O . ASP K 1 155 ? 66.346 48.527 44.520 1.00 84.48 ? 155 ASP K O 1 +ATOM 20223 C CB . ASP K 1 155 ? 63.225 49.177 43.619 1.00 89.29 ? 155 ASP K CB 1 +ATOM 20224 C CG . ASP K 1 155 ? 62.436 50.334 43.025 1.00 130.82 ? 155 ASP K CG 1 +ATOM 20225 O OD1 . ASP K 1 155 ? 62.991 51.065 42.166 1.00 196.65 ? 155 ASP K OD1 1 +ATOM 20226 O OD2 . ASP K 1 155 ? 61.287 50.554 43.449 1.00 123.77 ? 155 ASP K OD2 1 +ATOM 20227 N N . GLN K 1 156 ? 64.765 47.511 45.754 1.00 101.96 ? 156 GLN K N 1 +ATOM 20228 C CA . GLN K 1 156 ? 65.639 46.393 46.107 1.00 90.90 ? 156 GLN K CA 1 +ATOM 20229 C C . GLN K 1 156 ? 65.089 45.078 45.552 1.00 68.14 ? 156 GLN K C 1 +ATOM 20230 O O . GLN K 1 156 ? 63.887 44.945 45.324 1.00 53.96 ? 156 GLN K O 1 +ATOM 20231 C CB . GLN K 1 156 ? 65.812 46.313 47.628 1.00 99.99 ? 156 GLN K CB 1 +ATOM 20232 C CG . GLN K 1 156 ? 66.913 45.370 48.064 1.00 110.17 ? 156 GLN K CG 1 +ATOM 20233 C CD . GLN K 1 156 ? 67.450 45.700 49.439 1.00 99.61 ? 156 GLN K CD 1 +ATOM 20234 O OE1 . GLN K 1 156 ? 66.865 46.498 50.181 1.00 71.71 ? 156 GLN K OE1 1 +ATOM 20235 N NE2 . GLN K 1 156 ? 68.528 45.015 49.826 1.00 99.29 ? 156 GLN K NE2 1 +ATOM 20236 N N . ILE K 1 157 ? 65.980 44.127 45.317 1.00 49.94 ? 157 ILE K N 1 +ATOM 20237 C CA . ILE K 1 157 ? 65.585 42.801 44.922 1.00 63.64 ? 157 ILE K CA 1 +ATOM 20238 C C . ILE K 1 157 ? 66.599 41.798 45.482 1.00 65.01 ? 157 ILE K C 1 +ATOM 20239 O O . ILE K 1 157 ? 67.792 42.060 45.519 1.00 46.15 ? 157 ILE K O 1 +ATOM 20240 C CB . ILE K 1 157 ? 65.509 42.709 43.381 1.00 92.42 ? 157 ILE K CB 1 +ATOM 20241 C CG1 . ILE K 1 157 ? 64.553 41.579 42.947 1.00 118.61 ? 157 ILE K CG1 1 +ATOM 20242 C CG2 . ILE K 1 157 ? 66.890 42.503 42.776 1.00 78.53 ? 157 ILE K CG2 1 +ATOM 20243 C CD1 . ILE K 1 157 ? 64.265 41.554 41.454 1.00 118.22 ? 157 ILE K CD1 1 +ATOM 20244 N N . ALA K 1 158 ? 66.116 40.661 45.979 1.00 76.83 ? 158 ALA K N 1 +ATOM 20245 C CA . ALA K 1 158 ? 67.023 39.684 46.606 1.00 61.19 ? 158 ALA K CA 1 +ATOM 20246 C C . ALA K 1 158 ? 66.695 38.292 46.127 1.00 46.91 ? 158 ALA K C 1 +ATOM 20247 O O . ALA K 1 158 ? 65.544 38.022 45.711 1.00 60.79 ? 158 ALA K O 1 +ATOM 20248 C CB . ALA K 1 158 ? 66.945 39.760 48.118 1.00 52.64 ? 158 ALA K CB 1 +ATOM 20249 N N . VAL K 1 159 ? 67.705 37.442 46.120 1.00 31.80 ? 159 VAL K N 1 +ATOM 20250 C CA . VAL K 1 159 ? 67.581 36.158 45.515 1.00 37.25 ? 159 VAL K CA 1 +ATOM 20251 C C . VAL K 1 159 ? 68.286 35.140 46.347 1.00 50.46 ? 159 VAL K C 1 +ATOM 20252 O O . VAL K 1 159 ? 69.440 35.319 46.726 1.00 65.35 ? 159 VAL K O 1 +ATOM 20253 C CB . VAL K 1 159 ? 68.150 36.120 44.082 1.00 41.32 ? 159 VAL K CB 1 +ATOM 20254 C CG1 . VAL K 1 159 ? 68.474 34.703 43.647 1.00 43.06 ? 159 VAL K CG1 1 +ATOM 20255 C CG2 . VAL K 1 159 ? 67.142 36.713 43.097 1.00 57.66 ? 159 VAL K CG2 1 +ATOM 20256 N N . ASN K 1 160 ? 67.562 34.068 46.676 1.00 73.27 ? 160 ASN K N 1 +ATOM 20257 C CA . ASN K 1 160 ? 68.146 32.905 47.341 1.00 73.45 ? 160 ASN K CA 1 +ATOM 20258 C C . ASN K 1 160 ? 68.437 31.861 46.274 1.00 58.33 ? 160 ASN K C 1 +ATOM 20259 O O . ASN K 1 160 ? 67.583 31.567 45.429 1.00 38.30 ? 160 ASN K O 1 +ATOM 20260 C CB . ASN K 1 160 ? 67.166 32.353 48.381 1.00 86.94 ? 160 ASN K CB 1 +ATOM 20261 C CG . ASN K 1 160 ? 67.661 31.080 49.060 1.00 112.65 ? 160 ASN K CG 1 +ATOM 20262 O OD1 . ASN K 1 160 ? 68.106 30.132 48.409 1.00 145.68 ? 160 ASN K OD1 1 +ATOM 20263 N ND2 . ASN K 1 160 ? 67.507 31.023 50.368 1.00 122.31 ? 160 ASN K ND2 1 +ATOM 20264 N N . LEU K 1 161 ? 69.669 31.360 46.280 1.00 48.60 ? 161 LEU K N 1 +ATOM 20265 C CA . LEU K 1 161 ? 69.979 30.119 45.597 1.00 51.85 ? 161 LEU K CA 1 +ATOM 20266 C C . LEU K 1 161 ? 70.595 29.119 46.571 1.00 43.15 ? 161 LEU K C 1 +ATOM 20267 O O . LEU K 1 161 ? 71.272 29.493 47.488 1.00 40.02 ? 161 LEU K O 1 +ATOM 20268 C CB . LEU K 1 161 ? 70.948 30.369 44.447 1.00 56.95 ? 161 LEU K CB 1 +ATOM 20269 C CG . LEU K 1 161 ? 70.427 31.244 43.314 1.00 60.69 ? 161 LEU K CG 1 +ATOM 20270 C CD1 . LEU K 1 161 ? 71.564 31.559 42.360 1.00 71.39 ? 161 LEU K CD1 1 +ATOM 20271 C CD2 . LEU K 1 161 ? 69.279 30.525 42.594 1.00 55.02 ? 161 LEU K CD2 1 +ATOM 20272 N N . ARG K 1 162 ? 70.343 27.845 46.366 1.00 49.06 ? 162 ARG K N 1 +ATOM 20273 C CA . ARG K 1 162 ? 70.861 26.860 47.278 1.00 59.33 ? 162 ARG K CA 1 +ATOM 20274 C C . ARG K 1 162 ? 71.031 25.476 46.663 1.00 61.97 ? 162 ARG K C 1 +ATOM 20275 O O . ARG K 1 162 ? 70.150 24.945 45.979 1.00 65.97 ? 162 ARG K O 1 +ATOM 20276 C CB . ARG K 1 162 ? 70.003 26.786 48.545 1.00 92.28 ? 162 ARG K CB 1 +ATOM 20277 C CG . ARG K 1 162 ? 68.552 26.324 48.391 1.00 129.44 ? 162 ARG K CG 1 +ATOM 20278 C CD . ARG K 1 162 ? 67.982 25.909 49.751 1.00 135.98 ? 162 ARG K CD 1 +ATOM 20279 N NE . ARG K 1 162 ? 66.662 25.283 49.670 1.00 124.26 ? 162 ARG K NE 1 +ATOM 20280 C CZ . ARG K 1 162 ? 65.510 25.951 49.555 1.00 123.03 ? 162 ARG K CZ 1 +ATOM 20281 N NH1 . ARG K 1 162 ? 65.488 27.279 49.456 1.00 82.91 ? 162 ARG K NH1 1 +ATOM 20282 N NH2 . ARG K 1 162 ? 64.368 25.270 49.501 1.00 149.24 ? 162 ARG K NH2 1 +ATOM 20283 N N . VAL K 1 163 ? 72.217 24.927 46.879 1.00 75.96 ? 163 VAL K N 1 +ATOM 20284 C CA . VAL K 1 163 ? 72.585 23.593 46.389 1.00 84.17 ? 163 VAL K CA 1 +ATOM 20285 C C . VAL K 1 163 ? 72.123 22.527 47.358 1.00 72.33 ? 163 VAL K C 1 +ATOM 20286 O O . VAL K 1 163 ? 72.530 22.528 48.523 1.00 98.40 ? 163 VAL K O 1 +ATOM 20287 C CB . VAL K 1 163 ? 74.113 23.417 46.270 1.00 98.66 ? 163 VAL K CB 1 +ATOM 20288 C CG1 . VAL K 1 163 ? 74.452 21.995 45.788 1.00 75.48 ? 163 VAL K CG1 1 +ATOM 20289 C CG2 . VAL K 1 163 ? 74.715 24.508 45.380 1.00 109.22 ? 163 VAL K CG2 1 +ATOM 20290 N N . VAL K 1 164 ? 71.326 21.602 46.844 1.00 56.67 ? 164 VAL K N 1 +ATOM 20291 C CA . VAL K 1 164 ? 70.815 20.499 47.615 1.00 38.48 ? 164 VAL K CA 1 +ATOM 20292 C C . VAL K 1 164 ? 71.400 19.245 47.118 1.00 36.99 ? 164 VAL K C 1 +ATOM 20293 O O . VAL K 1 164 ? 71.463 19.019 45.888 1.00 49.27 ? 164 VAL K O 1 +ATOM 20294 C CB . VAL K 1 164 ? 69.317 20.402 47.449 1.00 32.14 ? 164 VAL K CB 1 +ATOM 20295 C CG1 . VAL K 1 164 ? 68.807 19.217 48.227 1.00 31.88 ? 164 VAL K CG1 1 +ATOM 20296 C CG2 . VAL K 1 164 ? 68.648 21.686 47.944 1.00 34.03 ? 164 VAL K CG2 1 +ATOM 20297 N N . ASN K 1 165 ? 71.862 18.437 48.040 1.00 41.17 ? 165 ASN K N 1 +ATOM 20298 C CA . ASN K 1 165 ? 72.376 17.133 47.664 1.00 75.90 ? 165 ASN K CA 1 +ATOM 20299 C C . ASN K 1 165 ? 71.272 16.090 47.445 1.00 80.74 ? 165 ASN K C 1 +ATOM 20300 O O . ASN K 1 165 ? 70.548 15.755 48.379 1.00 126.54 ? 165 ASN K O 1 +ATOM 20301 C CB . ASN K 1 165 ? 73.334 16.600 48.722 1.00 96.60 ? 165 ASN K CB 1 +ATOM 20302 C CG . ASN K 1 165 ? 73.955 15.291 48.306 1.00 102.45 ? 165 ASN K CG 1 +ATOM 20303 O OD1 . ASN K 1 165 ? 74.065 15.007 47.082 1.00 149.21 ? 165 ASN K OD1 1 +ATOM 20304 N ND2 . ASN K 1 165 ? 74.599 14.638 49.259 1.00 106.23 ? 165 ASN K ND2 1 +ATOM 20305 N N . VAL K 1 166 ? 71.181 15.554 46.226 1.00 84.80 ? 166 VAL K N 1 +ATOM 20306 C CA . VAL K 1 166 ? 70.128 14.612 45.847 1.00 63.87 ? 166 VAL K CA 1 +ATOM 20307 C C . VAL K 1 166 ? 70.260 13.378 46.689 1.00 68.03 ? 166 VAL K C 1 +ATOM 20308 O O . VAL K 1 166 ? 69.238 12.834 47.126 1.00 107.06 ? 166 VAL K O 1 +ATOM 20309 C CB . VAL K 1 166 ? 70.241 14.220 44.362 1.00 74.92 ? 166 VAL K CB 1 +ATOM 20310 C CG1 . VAL K 1 166 ? 69.646 12.844 44.088 1.00 89.26 ? 166 VAL K CG1 1 +ATOM 20311 C CG2 . VAL K 1 166 ? 69.629 15.300 43.472 1.00 57.23 ? 166 VAL K CG2 1 +ATOM 20312 N N . SER K 1 167 ? 71.503 12.961 46.970 1.00 60.22 ? 167 SER K N 1 +ATOM 20313 C CA . SER K 1 167 ? 71.740 11.698 47.640 1.00 59.22 ? 167 SER K CA 1 +ATOM 20314 C C . SER K 1 167 ? 71.374 11.716 49.141 1.00 72.33 ? 167 SER K C 1 +ATOM 20315 O O . SER K 1 167 ? 71.192 10.644 49.757 1.00 61.46 ? 167 SER K O 1 +ATOM 20316 C CB . SER K 1 167 ? 73.187 11.316 47.492 1.00 60.05 ? 167 SER K CB 1 +ATOM 20317 O OG . SER K 1 167 ? 73.608 11.495 46.167 1.00 56.80 ? 167 SER K OG 1 +ATOM 20318 N N . THR K 1 168 ? 71.195 12.912 49.720 1.00 73.22 ? 168 THR K N 1 +ATOM 20319 C CA . THR K 1 168 ? 70.787 13.022 51.145 1.00 63.42 ? 168 THR K CA 1 +ATOM 20320 C C . THR K 1 168 ? 69.634 14.013 51.481 1.00 65.40 ? 168 THR K C 1 +ATOM 20321 O O . THR K 1 168 ? 68.845 13.826 52.421 1.00 52.37 ? 168 THR K O 1 +ATOM 20322 C CB . THR K 1 168 ? 71.996 13.461 51.955 1.00 63.96 ? 168 THR K CB 1 +ATOM 20323 O OG1 . THR K 1 168 ? 72.543 14.615 51.346 1.00 32.93 ? 168 THR K OG1 1 +ATOM 20324 C CG2 . THR K 1 168 ? 73.008 12.326 52.003 1.00 82.58 ? 168 THR K CG2 1 +ATOM 20325 N N . GLY K 1 169 ? 69.531 15.080 50.706 1.00 64.87 ? 169 GLY K N 1 +ATOM 20326 C CA . GLY K 1 169 ? 68.590 16.131 51.020 1.00 49.47 ? 169 GLY K CA 1 +ATOM 20327 C C . GLY K 1 169 ? 69.288 17.218 51.811 1.00 51.23 ? 169 GLY K C 1 +ATOM 20328 O O . GLY K 1 169 ? 68.694 18.266 52.046 1.00 59.35 ? 169 GLY K O 1 +ATOM 20329 N N . GLU K 1 170 ? 70.519 16.954 52.294 1.00 43.34 ? 170 GLU K N 1 +ATOM 20330 C CA . GLU K 1 170 ? 71.326 17.996 52.943 1.00 39.46 ? 170 GLU K CA 1 +ATOM 20331 C C . GLU K 1 170 ? 71.378 19.122 51.959 1.00 37.12 ? 170 GLU K C 1 +ATOM 20332 O O . GLU K 1 170 ? 71.764 18.927 50.808 1.00 58.19 ? 170 GLU K O 1 +ATOM 20333 C CB . GLU K 1 170 ? 72.727 17.491 53.280 1.00 47.25 ? 170 GLU K CB 1 +ATOM 20334 C CG . GLU K 1 170 ? 72.778 16.600 54.521 1.00 88.18 ? 170 GLU K CG 1 +ATOM 20335 C CD . GLU K 1 170 ? 73.738 15.398 54.445 1.00 98.09 ? 170 GLU K CD 1 +ATOM 20336 O OE1 . GLU K 1 170 ? 74.287 15.147 53.373 1.00 70.42 ? 170 GLU K OE1 1 +ATOM 20337 O OE2 . GLU K 1 170 ? 74.005 14.761 55.501 1.00 112.24 ? 170 GLU K OE2 1 +ATOM 20338 N N . ILE K 1 171 ? 70.962 20.302 52.365 1.00 34.76 ? 171 ILE K N 1 +ATOM 20339 C CA . ILE K 1 171 ? 71.430 21.485 51.675 1.00 43.22 ? 171 ILE K CA 1 +ATOM 20340 C C . ILE K 1 171 ? 72.979 21.667 51.788 1.00 60.52 ? 171 ILE K C 1 +ATOM 20341 O O . ILE K 1 171 ? 73.517 21.695 52.894 1.00 57.65 ? 171 ILE K O 1 +ATOM 20342 C CB . ILE K 1 171 ? 70.730 22.742 52.197 1.00 30.45 ? 171 ILE K CB 1 +ATOM 20343 C CG1 . ILE K 1 171 ? 69.270 22.629 51.832 1.00 25.32 ? 171 ILE K CG1 1 +ATOM 20344 C CG2 . ILE K 1 171 ? 71.397 24.000 51.619 1.00 25.41 ? 171 ILE K CG2 1 +ATOM 20345 C CD1 . ILE K 1 171 ? 68.417 23.603 52.592 1.00 25.38 ? 171 ILE K CD1 1 +ATOM 20346 N N . LEU K 1 172 ? 73.692 21.733 50.649 1.00 69.31 ? 172 LEU K N 1 +ATOM 20347 C CA . LEU K 1 172 ? 75.161 21.838 50.669 1.00 79.36 ? 172 LEU K CA 1 +ATOM 20348 C C . LEU K 1 172 ? 75.666 23.303 50.632 1.00 96.24 ? 172 LEU K C 1 +ATOM 20349 O O . LEU K 1 172 ? 76.861 23.603 50.880 1.00 66.39 ? 172 LEU K O 1 +ATOM 20350 C CB . LEU K 1 172 ? 75.791 21.043 49.526 1.00 84.99 ? 172 LEU K CB 1 +ATOM 20351 C CG . LEU K 1 172 ? 76.129 19.549 49.695 1.00 104.19 ? 172 LEU K CG 1 +ATOM 20352 C CD1 . LEU K 1 172 ? 75.219 18.977 50.746 1.00 102.93 ? 172 LEU K CD1 1 +ATOM 20353 C CD2 . LEU K 1 172 ? 76.192 18.684 48.441 1.00 98.59 ? 172 LEU K CD2 1 +ATOM 20354 N N . SER K 1 173 ? 74.734 24.217 50.340 1.00 84.16 ? 173 SER K N 1 +ATOM 20355 C CA . SER K 1 173 ? 75.056 25.636 50.265 1.00 67.41 ? 173 SER K CA 1 +ATOM 20356 C C . SER K 1 173 ? 73.814 26.481 50.087 1.00 59.47 ? 173 SER K C 1 +ATOM 20357 O O . SER K 1 173 ? 72.994 26.222 49.236 1.00 65.12 ? 173 SER K O 1 +ATOM 20358 C CB . SER K 1 173 ? 76.004 25.915 49.090 1.00 67.09 ? 173 SER K CB 1 +ATOM 20359 O OG . SER K 1 173 ? 76.054 27.303 48.826 1.00 86.25 ? 173 SER K OG 1 +ATOM 20360 N N . SER K 1 174 ? 73.691 27.521 50.891 1.00 76.85 ? 174 SER K N 1 +ATOM 20361 C CA . SER K 1 174 ? 72.664 28.549 50.679 1.00 79.01 ? 174 SER K CA 1 +ATOM 20362 C C . SER K 1 174 ? 73.353 29.891 50.551 1.00 92.83 ? 174 SER K C 1 +ATOM 20363 O O . SER K 1 174 ? 74.256 30.220 51.330 1.00 106.24 ? 174 SER K O 1 +ATOM 20364 C CB . SER K 1 174 ? 71.646 28.598 51.852 1.00 79.42 ? 174 SER K CB 1 +ATOM 20365 O OG . SER K 1 174 ? 70.520 29.412 51.572 1.00 40.43 ? 174 SER K OG 1 +ATOM 20366 N N . VAL K 1 175 ? 72.893 30.682 49.591 1.00 104.84 ? 175 VAL K N 1 +ATOM 20367 C CA . VAL K 1 175 ? 73.417 32.033 49.385 1.00 86.07 ? 175 VAL K CA 1 +ATOM 20368 C C . VAL K 1 175 ? 72.307 33.049 49.134 1.00 66.32 ? 175 VAL K C 1 +ATOM 20369 O O . VAL K 1 175 ? 71.301 32.737 48.480 1.00 48.70 ? 175 VAL K O 1 +ATOM 20370 C CB . VAL K 1 175 ? 74.410 32.062 48.214 1.00 98.40 ? 175 VAL K CB 1 +ATOM 20371 C CG1 . VAL K 1 175 ? 75.616 31.184 48.514 1.00 114.73 ? 175 VAL K CG1 1 +ATOM 20372 C CG2 . VAL K 1 175 ? 73.760 31.593 46.924 1.00 112.39 ? 175 VAL K CG2 1 +ATOM 20373 N N . ASN K 1 176 ? 72.519 34.257 49.641 1.00 61.38 ? 176 ASN K N 1 +ATOM 20374 C CA . ASN K 1 176 ? 71.521 35.309 49.584 1.00 76.74 ? 176 ASN K CA 1 +ATOM 20375 C C . ASN K 1 176 ? 72.041 36.596 48.932 1.00 77.73 ? 176 ASN K C 1 +ATOM 20376 O O . ASN K 1 176 ? 72.581 37.436 49.629 1.00 91.70 ? 176 ASN K O 1 +ATOM 20377 C CB . ASN K 1 176 ? 71.035 35.586 51.007 1.00 76.17 ? 176 ASN K CB 1 +ATOM 20378 C CG . ASN K 1 176 ? 69.717 34.857 51.309 1.00 93.51 ? 176 ASN K CG 1 +ATOM 20379 O OD1 . ASN K 1 176 ? 69.394 33.906 50.600 1.00 60.69 ? 176 ASN K OD1 1 +ATOM 20380 N ND2 . ASN K 1 176 ? 69.007 35.219 52.411 1.00 116.64 ? 176 ASN K ND2 1 +ATOM 20381 N N . THR K 1 177 ? 71.797 36.780 47.625 1.00 62.88 ? 177 THR K N 1 +ATOM 20382 C CA . THR K 1 177 ? 72.281 37.960 46.900 1.00 49.38 ? 177 THR K CA 1 +ATOM 20383 C C . THR K 1 177 ? 71.193 39.031 46.761 1.00 56.80 ? 177 THR K C 1 +ATOM 20384 O O . THR K 1 177 ? 70.012 38.767 46.968 1.00 49.88 ? 177 THR K O 1 +ATOM 20385 C CB . THR K 1 177 ? 72.777 37.605 45.505 1.00 42.37 ? 177 THR K CB 1 +ATOM 20386 O OG1 . THR K 1 177 ? 71.668 37.254 44.677 1.00 45.60 ? 177 THR K OG1 1 +ATOM 20387 C CG2 . THR K 1 177 ? 73.749 36.437 45.543 1.00 43.97 ? 177 THR K CG2 1 +ATOM 20388 N N . SER K 1 178 ? 71.622 40.258 46.491 1.00 68.42 ? 178 SER K N 1 +ATOM 20389 C CA . SER K 1 178 ? 70.726 41.419 46.494 1.00 64.50 ? 178 SER K CA 1 +ATOM 20390 C C . SER K 1 178 ? 71.215 42.433 45.502 1.00 67.79 ? 178 SER K C 1 +ATOM 20391 O O . SER K 1 178 ? 72.424 42.556 45.237 1.00 88.94 ? 178 SER K O 1 +ATOM 20392 C CB . SER K 1 178 ? 70.633 42.087 47.890 1.00 65.64 ? 178 SER K CB 1 +ATOM 20393 O OG . SER K 1 178 ? 70.040 43.386 47.815 1.00 41.53 ? 178 SER K OG 1 +ATOM 20394 N N . LYS K 1 179 ? 70.291 43.225 45.006 1.00 70.19 ? 179 LYS K N 1 +ATOM 20395 C CA . LYS K 1 179 ? 70.630 44.168 43.950 1.00 89.69 ? 179 LYS K CA 1 +ATOM 20396 C C . LYS K 1 179 ? 69.624 45.323 43.877 1.00 76.89 ? 179 LYS K C 1 +ATOM 20397 O O . LYS K 1 179 ? 68.454 45.179 44.227 1.00 63.93 ? 179 LYS K O 1 +ATOM 20398 C CB . LYS K 1 179 ? 70.652 43.429 42.619 1.00 115.29 ? 179 LYS K CB 1 +ATOM 20399 C CG . LYS K 1 179 ? 71.712 43.905 41.643 1.00 101.98 ? 179 LYS K CG 1 +ATOM 20400 C CD . LYS K 1 179 ? 71.121 44.949 40.710 1.00 110.94 ? 179 LYS K CD 1 +ATOM 20401 C CE . LYS K 1 179 ? 72.198 45.545 39.841 1.00 121.53 ? 179 LYS K CE 1 +ATOM 20402 N NZ . LYS K 1 179 ? 71.720 46.763 39.146 1.00 118.83 ? 179 LYS K NZ 1 +ATOM 20403 N N . THR K 1 180 ? 70.119 46.479 43.475 1.00 55.76 ? 180 THR K N 1 +ATOM 20404 C CA . THR K 1 180 ? 69.358 47.675 43.575 1.00 62.10 ? 180 THR K CA 1 +ATOM 20405 C C . THR K 1 180 ? 68.987 48.084 42.187 1.00 86.04 ? 180 THR K C 1 +ATOM 20406 O O . THR K 1 180 ? 69.868 48.242 41.342 1.00 84.88 ? 180 THR K O 1 +ATOM 20407 C CB . THR K 1 180 ? 70.260 48.820 44.092 1.00 62.41 ? 180 THR K CB 1 +ATOM 20408 O OG1 . THR K 1 180 ? 71.017 48.368 45.209 1.00 83.67 ? 180 THR K OG1 1 +ATOM 20409 C CG2 . THR K 1 180 ? 69.467 50.067 44.457 1.00 52.68 ? 180 THR K CG2 1 +ATOM 20410 N N . ILE K 1 181 ? 67.731 48.490 42.027 1.00 123.76 ? 181 ILE K N 1 +ATOM 20411 C CA . ILE K 1 181 ? 67.242 49.030 40.758 1.00 115.59 ? 181 ILE K CA 1 +ATOM 20412 C C . ILE K 1 181 ? 67.125 50.567 40.794 1.00 117.63 ? 181 ILE K C 1 +ATOM 20413 O O . ILE K 1 181 ? 66.358 51.126 41.588 1.00 153.27 ? 181 ILE K O 1 +ATOM 20414 C CB . ILE K 1 181 ? 65.872 48.407 40.396 1.00 101.55 ? 181 ILE K CB 1 +ATOM 20415 C CG1 . ILE K 1 181 ? 65.951 46.884 40.474 1.00 102.82 ? 181 ILE K CG1 1 +ATOM 20416 C CG2 . ILE K 1 181 ? 65.441 48.815 39.003 1.00 123.21 ? 181 ILE K CG2 1 +ATOM 20417 C CD1 . ILE K 1 181 ? 65.000 46.284 41.480 1.00 113.82 ? 181 ILE K CD1 1 +ATOM 20418 N N . LEU K 1 182 ? 67.909 51.232 39.950 1.00 92.37 ? 182 LEU K N 1 +ATOM 20419 C CA . LEU K 1 182 ? 67.966 52.684 39.921 1.00 88.52 ? 182 LEU K CA 1 +ATOM 20420 C C . LEU K 1 182 ? 66.987 53.298 38.926 1.00 89.50 ? 182 LEU K C 1 +ATOM 20421 O O . LEU K 1 182 ? 66.873 52.851 37.780 1.00 82.17 ? 182 LEU K O 1 +ATOM 20422 C CB . LEU K 1 182 ? 69.389 53.137 39.585 1.00 93.03 ? 182 LEU K CB 1 +ATOM 20423 C CG . LEU K 1 182 ? 69.604 54.651 39.483 1.00 89.35 ? 182 LEU K CG 1 +ATOM 20424 C CD1 . LEU K 1 182 ? 69.312 55.392 40.792 1.00 82.54 ? 182 LEU K CD1 1 +ATOM 20425 C CD2 . LEU K 1 182 ? 71.028 54.888 39.016 1.00 82.99 ? 182 LEU K CD2 1 +ATOM 20426 N N . SER K 1 183 ? 66.377 54.406 39.338 1.00 105.94 ? 183 SER K N 1 +ATOM 20427 C CA . SER K 1 183 ? 65.551 55.215 38.453 1.00 150.38 ? 183 SER K CA 1 +ATOM 20428 C C . SER K 1 183 ? 65.807 56.707 38.695 1.00 157.89 ? 183 SER K C 1 +ATOM 20429 O O . SER K 1 183 ? 65.965 57.137 39.837 1.00 161.15 ? 183 SER K O 1 +ATOM 20430 C CB . SER K 1 183 ? 64.072 54.892 38.686 1.00 158.20 ? 183 SER K CB 1 +ATOM 20431 O OG . SER K 1 183 ? 63.896 53.504 38.930 1.00 146.67 ? 183 SER K OG 1 +ATOM 20432 N N . TYR K 1 184 ? 65.843 57.493 37.619 1.00 137.79 ? 184 TYR K N 1 +ATOM 20433 C CA . TYR K 1 184 ? 65.979 58.946 37.746 1.00 112.55 ? 184 TYR K CA 1 +ATOM 20434 C C . TYR K 1 184 ? 65.352 59.753 36.613 1.00 102.09 ? 184 TYR K C 1 +ATOM 20435 O O . TYR K 1 184 ? 65.135 59.264 35.498 1.00 118.99 ? 184 TYR K O 1 +ATOM 20436 C CB . TYR K 1 184 ? 67.444 59.347 37.903 1.00 87.21 ? 184 TYR K CB 1 +ATOM 20437 C CG . TYR K 1 184 ? 68.318 58.918 36.755 1.00 76.52 ? 184 TYR K CG 1 +ATOM 20438 C CD1 . TYR K 1 184 ? 68.459 59.705 35.625 1.00 63.29 ? 184 TYR K CD1 1 +ATOM 20439 C CD2 . TYR K 1 184 ? 68.992 57.699 36.793 1.00 87.16 ? 184 TYR K CD2 1 +ATOM 20440 C CE1 . TYR K 1 184 ? 69.255 59.300 34.566 1.00 62.90 ? 184 TYR K CE1 1 +ATOM 20441 C CE2 . TYR K 1 184 ? 69.831 57.303 35.758 1.00 84.57 ? 184 TYR K CE2 1 +ATOM 20442 C CZ . TYR K 1 184 ? 69.977 58.117 34.652 1.00 73.87 ? 184 TYR K CZ 1 +ATOM 20443 O OH . TYR K 1 184 ? 70.772 57.687 33.607 1.00 53.68 ? 184 TYR K OH 1 +ATOM 20444 N N . GLU K 1 185 ? 65.030 60.995 36.951 1.00 108.00 ? 185 GLU K N 1 +ATOM 20445 C CA . GLU K 1 185 ? 64.289 61.890 36.101 1.00 129.40 ? 185 GLU K CA 1 +ATOM 20446 C C . GLU K 1 185 ? 64.905 63.276 36.116 1.00 154.11 ? 185 GLU K C 1 +ATOM 20447 O O . GLU K 1 185 ? 64.863 63.973 37.116 1.00 166.52 ? 185 GLU K O 1 +ATOM 20448 C CB . GLU K 1 185 ? 62.831 61.903 36.560 1.00 131.25 ? 185 GLU K CB 1 +ATOM 20449 C CG . GLU K 1 185 ? 61.921 62.934 35.927 1.00 140.55 ? 185 GLU K CG 1 +ATOM 20450 C CD . GLU K 1 185 ? 60.465 62.677 36.280 1.00 145.13 ? 185 GLU K CD 1 +ATOM 20451 O OE1 . GLU K 1 185 ? 60.177 61.668 36.961 1.00 148.77 ? 185 GLU K OE1 1 +ATOM 20452 O OE2 . GLU K 1 185 ? 59.603 63.472 35.864 1.00 156.57 ? 185 GLU K OE2 1 +ATOM 20453 N N . VAL K 1 186 ? 65.545 63.631 35.007 1.00 168.58 ? 186 VAL K N 1 +ATOM 20454 C CA . VAL K 1 186 ? 66.184 64.928 34.849 1.00 141.07 ? 186 VAL K CA 1 +ATOM 20455 C C . VAL K 1 186 ? 65.292 65.815 34.000 1.00 148.56 ? 186 VAL K C 1 +ATOM 20456 O O . VAL K 1 186 ? 64.691 65.374 33.016 1.00 167.45 ? 186 VAL K O 1 +ATOM 20457 C CB . VAL K 1 186 ? 67.566 64.804 34.181 1.00 112.47 ? 186 VAL K CB 1 +ATOM 20458 C CG1 . VAL K 1 186 ? 68.282 66.140 34.206 1.00 109.83 ? 186 VAL K CG1 1 +ATOM 20459 C CG2 . VAL K 1 186 ? 68.398 63.743 34.877 1.00 107.43 ? 186 VAL K CG2 1 +ATOM 20460 N N . GLN K 1 187 ? 65.182 67.070 34.395 1.00 136.59 ? 187 GLN K N 1 +ATOM 20461 C CA . GLN K 1 187 ? 64.273 67.947 33.717 1.00 150.37 ? 187 GLN K CA 1 +ATOM 20462 C C . GLN K 1 187 ? 64.766 69.405 33.784 1.00 175.30 ? 187 GLN K C 1 +ATOM 20463 O O . GLN K 1 187 ? 65.303 69.863 34.801 1.00 223.74 ? 187 GLN K O 1 +ATOM 20464 C CB . GLN K 1 187 ? 62.873 67.718 34.259 1.00 131.78 ? 187 GLN K CB 1 +ATOM 20465 C CG . GLN K 1 187 ? 61.854 68.692 33.705 1.00 135.57 ? 187 GLN K CG 1 +ATOM 20466 C CD . GLN K 1 187 ? 60.520 68.687 34.480 1.00 135.34 ? 187 GLN K CD 1 +ATOM 20467 O OE1 . GLN K 1 187 ? 59.520 69.355 34.126 1.00 139.89 ? 187 GLN K OE1 1 +ATOM 20468 N NE2 . GLN K 1 187 ? 60.512 67.934 35.558 1.00 142.81 ? 187 GLN K NE2 1 +ATOM 20469 N N . ALA K 1 188 ? 64.716 70.088 32.645 1.00 192.10 ? 188 ALA K N 1 +ATOM 20470 C CA . ALA K 1 188 ? 65.171 71.473 32.570 1.00 177.44 ? 188 ALA K CA 1 +ATOM 20471 C C . ALA K 1 188 ? 64.209 72.286 31.705 1.00 166.03 ? 188 ALA K C 1 +ATOM 20472 O O . ALA K 1 188 ? 63.721 71.808 30.697 1.00 161.51 ? 188 ALA K O 1 +ATOM 20473 C CB . ALA K 1 188 ? 66.596 71.546 32.036 1.00 141.22 ? 188 ALA K CB 1 +ATOM 20474 N N . GLY K 1 189 ? 63.909 73.503 32.130 1.00 144.81 ? 189 GLY K N 1 +ATOM 20475 C CA . GLY K 1 189 ? 62.998 74.361 31.401 1.00 144.08 ? 189 GLY K CA 1 +ATOM 20476 C C . GLY K 1 189 ? 63.444 75.808 31.414 1.00 171.46 ? 189 GLY K C 1 +ATOM 20477 O O . GLY K 1 189 ? 63.868 76.329 32.443 1.00 195.48 ? 189 GLY K O 1 +ATOM 20478 N N . VAL K 1 190 ? 63.325 76.465 30.267 1.00 181.00 ? 190 VAL K N 1 +ATOM 20479 C CA . VAL K 1 190 ? 63.620 77.881 30.162 1.00 165.55 ? 190 VAL K CA 1 +ATOM 20480 C C . VAL K 1 190 ? 62.317 78.654 29.883 1.00 165.56 ? 190 VAL K C 1 +ATOM 20481 O O . VAL K 1 190 ? 61.503 78.247 29.050 1.00 168.54 ? 190 VAL K O 1 +ATOM 20482 C CB . VAL K 1 190 ? 64.666 78.142 29.059 1.00 122.25 ? 190 VAL K CB 1 +ATOM 20483 C CG1 . VAL K 1 190 ? 65.145 79.586 29.134 1.00 121.88 ? 190 VAL K CG1 1 +ATOM 20484 C CG2 . VAL K 1 190 ? 65.826 77.155 29.174 1.00 83.53 ? 190 VAL K CG2 1 +ATOM 20485 N N . PHE K 1 191 ? 62.124 79.772 30.581 1.00 152.61 ? 191 PHE K N 1 +ATOM 20486 C CA . PHE K 1 191 ? 60.850 80.491 30.538 1.00 147.51 ? 191 PHE K CA 1 +ATOM 20487 C C . PHE K 1 191 ? 61.083 81.992 30.355 1.00 157.85 ? 191 PHE K C 1 +ATOM 20488 O O . PHE K 1 191 ? 61.908 82.588 31.056 1.00 182.92 ? 191 PHE K O 1 +ATOM 20489 C CB . PHE K 1 191 ? 60.063 80.227 31.827 1.00 152.03 ? 191 PHE K CB 1 +ATOM 20490 C CG . PHE K 1 191 ? 58.587 80.465 31.700 1.00 148.72 ? 191 PHE K CG 1 +ATOM 20491 C CD1 . PHE K 1 191 ? 58.083 81.757 31.623 1.00 151.97 ? 191 PHE K CD1 1 +ATOM 20492 C CD2 . PHE K 1 191 ? 57.696 79.399 31.686 1.00 163.55 ? 191 PHE K CD2 1 +ATOM 20493 C CE1 . PHE K 1 191 ? 56.717 81.984 31.527 1.00 145.23 ? 191 PHE K CE1 1 +ATOM 20494 C CE2 . PHE K 1 191 ? 56.330 79.619 31.585 1.00 171.51 ? 191 PHE K CE2 1 +ATOM 20495 C CZ . PHE K 1 191 ? 55.839 80.914 31.511 1.00 148.23 ? 191 PHE K CZ 1 +ATOM 20496 N N . LEU K 1 200 ? 58.328 83.048 25.457 1.00 119.38 ? 200 LEU K N 1 +ATOM 20497 C CA . LEU K 1 200 ? 59.242 81.936 25.255 1.00 159.68 ? 200 LEU K CA 1 +ATOM 20498 C C . LEU K 1 200 ? 59.163 80.953 26.416 1.00 214.24 ? 200 LEU K C 1 +ATOM 20499 O O . LEU K 1 200 ? 59.596 81.265 27.532 1.00 267.83 ? 200 LEU K O 1 +ATOM 20500 C CB . LEU K 1 200 ? 60.701 82.414 25.096 1.00 140.35 ? 200 LEU K CB 1 +ATOM 20501 C CG . LEU K 1 200 ? 61.755 81.279 25.079 1.00 121.49 ? 200 LEU K CG 1 +ATOM 20502 C CD1 . LEU K 1 200 ? 62.183 80.971 23.657 1.00 107.58 ? 200 LEU K CD1 1 +ATOM 20503 C CD2 . LEU K 1 200 ? 62.963 81.567 25.973 1.00 111.55 ? 200 LEU K CD2 1 +ATOM 20504 N N . GLU K 1 201 ? 58.672 79.747 26.131 1.00 242.48 ? 201 GLU K N 1 +ATOM 20505 C CA . GLU K 1 201 ? 58.925 78.584 26.982 1.00 229.82 ? 201 GLU K CA 1 +ATOM 20506 C C . GLU K 1 201 ? 59.646 77.490 26.204 1.00 223.99 ? 201 GLU K C 1 +ATOM 20507 O O . GLU K 1 201 ? 59.463 77.354 24.992 1.00 267.89 ? 201 GLU K O 1 +ATOM 20508 C CB . GLU K 1 201 ? 57.626 78.025 27.540 1.00 197.94 ? 201 GLU K CB 1 +ATOM 20509 C CG . GLU K 1 201 ? 57.842 77.153 28.765 1.00 192.63 ? 201 GLU K CG 1 +ATOM 20510 C CD . GLU K 1 201 ? 56.552 76.596 29.336 1.00 217.87 ? 201 GLU K CD 1 +ATOM 20511 O OE1 . GLU K 1 201 ? 55.599 77.377 29.556 1.00 264.01 ? 201 GLU K OE1 1 +ATOM 20512 O OE2 . GLU K 1 201 ? 56.486 75.371 29.570 1.00 221.96 ? 201 GLU K OE2 1 +ATOM 20513 N N . GLY K 1 202 ? 60.511 76.751 26.893 1.00 200.97 ? 202 GLY K N 1 +ATOM 20514 C CA . GLY K 1 202 ? 61.195 75.611 26.292 1.00 196.80 ? 202 GLY K CA 1 +ATOM 20515 C C . GLY K 1 202 ? 61.572 74.589 27.344 1.00 201.09 ? 202 GLY K C 1 +ATOM 20516 O O . GLY K 1 202 ? 62.220 74.918 28.336 1.00 245.26 ? 202 GLY K O 1 +ATOM 20517 N N . GLU K 1 203 ? 61.166 73.339 27.141 1.00 187.39 ? 203 GLU K N 1 +ATOM 20518 C CA . GLU K 1 203 ? 61.408 72.297 28.141 1.00 150.72 ? 203 GLU K CA 1 +ATOM 20519 C C . GLU K 1 203 ? 62.065 71.045 27.570 1.00 145.03 ? 203 GLU K C 1 +ATOM 20520 O O . GLU K 1 203 ? 61.704 70.568 26.497 1.00 147.14 ? 203 GLU K O 1 +ATOM 20521 C CB . GLU K 1 203 ? 60.107 71.935 28.831 1.00 144.38 ? 203 GLU K CB 1 +ATOM 20522 C CG . GLU K 1 203 ? 59.548 73.074 29.682 1.00 171.43 ? 203 GLU K CG 1 +ATOM 20523 C CD . GLU K 1 203 ? 58.307 72.704 30.482 1.00 198.82 ? 203 GLU K CD 1 +ATOM 20524 O OE1 . GLU K 1 203 ? 57.732 71.625 30.233 1.00 249.08 ? 203 GLU K OE1 1 +ATOM 20525 O OE2 . GLU K 1 203 ? 57.865 73.528 31.321 1.00 207.71 ? 203 GLU K OE2 1 +ATOM 20526 N N . VAL K 1 204 ? 63.068 70.555 28.289 1.00 132.46 ? 204 VAL K N 1 +ATOM 20527 C CA . VAL K 1 204 ? 63.705 69.285 28.000 1.00 134.84 ? 204 VAL K CA 1 +ATOM 20528 C C . VAL K 1 204 ? 63.546 68.383 29.218 1.00 169.20 ? 204 VAL K C 1 +ATOM 20529 O O . VAL K 1 204 ? 63.723 68.819 30.352 1.00 191.89 ? 204 VAL K O 1 +ATOM 20530 C CB . VAL K 1 204 ? 65.200 69.466 27.646 1.00 90.57 ? 204 VAL K CB 1 +ATOM 20531 C CG1 . VAL K 1 204 ? 65.953 68.137 27.718 1.00 82.80 ? 204 VAL K CG1 1 +ATOM 20532 C CG2 . VAL K 1 204 ? 65.317 70.082 26.261 1.00 88.58 ? 204 VAL K CG2 1 +ATOM 20533 N N . GLY K 1 205 ? 63.166 67.134 28.971 1.00 194.68 ? 205 GLY K N 1 +ATOM 20534 C CA . GLY K 1 205 ? 63.041 66.144 30.029 1.00 182.44 ? 205 GLY K CA 1 +ATOM 20535 C C . GLY K 1 205 ? 63.649 64.810 29.617 1.00 178.11 ? 205 GLY K C 1 +ATOM 20536 O O . GLY K 1 205 ? 63.652 64.452 28.434 1.00 232.18 ? 205 GLY K O 1 +ATOM 20537 N N . TYR K 1 206 ? 64.176 64.078 30.590 1.00 131.92 ? 206 TYR K N 1 +ATOM 20538 C CA . TYR K 1 206 ? 64.700 62.731 30.357 1.00 96.31 ? 206 TYR K CA 1 +ATOM 20539 C C . TYR K 1 206 ? 64.495 61.874 31.582 1.00 105.72 ? 206 TYR K C 1 +ATOM 20540 O O . TYR K 1 206 ? 64.623 62.354 32.698 1.00 114.76 ? 206 TYR K O 1 +ATOM 20541 C CB . TYR K 1 206 ? 66.184 62.774 30.041 1.00 78.56 ? 206 TYR K CB 1 +ATOM 20542 C CG . TYR K 1 206 ? 66.799 61.402 29.872 1.00 71.38 ? 206 TYR K CG 1 +ATOM 20543 C CD1 . TYR K 1 206 ? 66.619 60.675 28.694 1.00 82.07 ? 206 TYR K CD1 1 +ATOM 20544 C CD2 . TYR K 1 206 ? 67.581 60.842 30.876 1.00 74.19 ? 206 TYR K CD2 1 +ATOM 20545 C CE1 . TYR K 1 206 ? 67.219 59.438 28.518 1.00 101.69 ? 206 TYR K CE1 1 +ATOM 20546 C CE2 . TYR K 1 206 ? 68.183 59.607 30.718 1.00 81.01 ? 206 TYR K CE2 1 +ATOM 20547 C CZ . TYR K 1 206 ? 68.012 58.912 29.539 1.00 107.31 ? 206 TYR K CZ 1 +ATOM 20548 O OH . TYR K 1 206 ? 68.616 57.683 29.380 1.00 125.25 ? 206 TYR K OH 1 +ATOM 20549 N N . THR K 1 207 ? 64.138 60.608 31.378 1.00 117.65 ? 207 THR K N 1 +ATOM 20550 C CA . THR K 1 207 ? 63.921 59.674 32.494 1.00 99.23 ? 207 THR K CA 1 +ATOM 20551 C C . THR K 1 207 ? 64.513 58.300 32.184 1.00 87.19 ? 207 THR K C 1 +ATOM 20552 O O . THR K 1 207 ? 64.403 57.798 31.059 1.00 81.65 ? 207 THR K O 1 +ATOM 20553 C CB . THR K 1 207 ? 62.426 59.490 32.814 1.00 87.24 ? 207 THR K CB 1 +ATOM 20554 O OG1 . THR K 1 207 ? 61.759 58.927 31.679 1.00 121.83 ? 207 THR K OG1 1 +ATOM 20555 C CG2 . THR K 1 207 ? 61.771 60.811 33.152 1.00 83.35 ? 207 THR K CG2 1 +ATOM 20556 N N . SER K 1 208 ? 65.198 57.724 33.159 1.00 90.48 ? 208 SER K N 1 +ATOM 20557 C CA . SER K 1 208 ? 65.829 56.427 32.956 1.00 91.97 ? 208 SER K CA 1 +ATOM 20558 C C . SER K 1 208 ? 65.542 55.486 34.110 1.00 111.42 ? 208 SER K C 1 +ATOM 20559 O O . SER K 1 208 ? 65.814 55.801 35.269 1.00 134.75 ? 208 SER K O 1 +ATOM 20560 C CB . SER K 1 208 ? 67.343 56.552 32.748 1.00 82.19 ? 208 SER K CB 1 +ATOM 20561 O OG . SER K 1 208 ? 67.952 55.259 32.703 1.00 67.95 ? 208 SER K OG 1 +ATOM 20562 N N . ASN K 1 209 ? 65.015 54.314 33.767 1.00 120.60 ? 209 ASN K N 1 +ATOM 20563 C CA . ASN K 1 209 ? 64.826 53.219 34.710 1.00 104.55 ? 209 ASN K CA 1 +ATOM 20564 C C . ASN K 1 209 ? 65.747 52.075 34.364 1.00 96.33 ? 209 ASN K C 1 +ATOM 20565 O O . ASN K 1 209 ? 65.857 51.687 33.201 1.00 120.63 ? 209 ASN K O 1 +ATOM 20566 C CB . ASN K 1 209 ? 63.388 52.729 34.660 1.00 94.37 ? 209 ASN K CB 1 +ATOM 20567 C CG . ASN K 1 209 ? 62.433 53.749 35.218 1.00 92.80 ? 209 ASN K CG 1 +ATOM 20568 O OD1 . ASN K 1 209 ? 62.202 53.799 36.419 1.00 112.07 ? 209 ASN K OD1 1 +ATOM 20569 N ND2 . ASN K 1 209 ? 61.817 54.517 34.341 1.00 96.92 ? 209 ASN K ND2 1 +ATOM 20570 N N . GLU K 1 210 ? 66.363 51.500 35.379 1.00 77.50 ? 210 GLU K N 1 +ATOM 20571 C CA . GLU K 1 210 ? 67.005 50.217 35.196 1.00 92.37 ? 210 GLU K CA 1 +ATOM 20572 C C . GLU K 1 210 ? 65.943 49.160 34.911 1.00 82.13 ? 210 GLU K C 1 +ATOM 20573 O O . GLU K 1 210 ? 64.852 49.169 35.496 1.00 75.04 ? 210 GLU K O 1 +ATOM 20574 C CB . GLU K 1 210 ? 67.794 49.840 36.451 1.00 121.43 ? 210 GLU K CB 1 +ATOM 20575 C CG . GLU K 1 210 ? 69.183 49.286 36.201 1.00 128.79 ? 210 GLU K CG 1 +ATOM 20576 C CD . GLU K 1 210 ? 70.059 49.327 37.453 1.00 139.10 ? 210 GLU K CD 1 +ATOM 20577 O OE1 . GLU K 1 210 ? 69.863 50.205 38.340 1.00 96.83 ? 210 GLU K OE1 1 +ATOM 20578 O OE2 . GLU K 1 210 ? 71.005 48.518 37.499 1.00 185.55 ? 210 GLU K OE2 1 +ATOM 20579 N N . PRO K 1 211 ? 66.277 48.209 34.057 1.00 83.03 ? 211 PRO K N 1 +ATOM 20580 C CA . PRO K 1 211 ? 65.367 47.088 33.904 1.00 127.13 ? 211 PRO K CA 1 +ATOM 20581 C C . PRO K 1 211 ? 65.441 46.123 35.094 1.00 127.54 ? 211 PRO K C 1 +ATOM 20582 O O . PRO K 1 211 ? 66.521 45.632 35.418 1.00 82.55 ? 211 PRO K O 1 +ATOM 20583 C CB . PRO K 1 211 ? 65.856 46.411 32.608 1.00 157.34 ? 211 PRO K CB 1 +ATOM 20584 C CG . PRO K 1 211 ? 66.697 47.440 31.918 1.00 128.53 ? 211 PRO K CG 1 +ATOM 20585 C CD . PRO K 1 211 ? 67.325 48.212 33.036 1.00 90.39 ? 211 PRO K CD 1 +ATOM 20586 N N . VAL K 1 212 ? 64.282 45.830 35.690 1.00 131.73 ? 212 VAL K N 1 +ATOM 20587 C CA . VAL K 1 212 ? 64.185 44.886 36.801 1.00 108.14 ? 212 VAL K CA 1 +ATOM 20588 C C . VAL K 1 212 ? 64.571 43.489 36.328 1.00 97.36 ? 212 VAL K C 1 +ATOM 20589 O O . VAL K 1 212 ? 65.312 42.764 36.993 1.00 102.66 ? 212 VAL K O 1 +ATOM 20590 C CB . VAL K 1 212 ? 62.754 44.813 37.353 1.00 102.37 ? 212 VAL K CB 1 +ATOM 20591 C CG1 . VAL K 1 212 ? 62.729 43.947 38.600 1.00 106.50 ? 212 VAL K CG1 1 +ATOM 20592 C CG2 . VAL K 1 212 ? 62.212 46.209 37.663 1.00 128.87 ? 212 VAL K CG2 1 +ATOM 20593 N N . MET K 1 213 ? 64.076 43.159 35.148 1.00 80.63 ? 213 MET K N 1 +ATOM 20594 C CA . MET K 1 213 ? 64.569 42.069 34.315 1.00 84.93 ? 213 MET K CA 1 +ATOM 20595 C C . MET K 1 213 ? 66.086 41.819 34.387 1.00 84.88 ? 213 MET K C 1 +ATOM 20596 O O . MET K 1 213 ? 66.560 40.698 34.660 1.00 89.97 ? 213 MET K O 1 +ATOM 20597 C CB . MET K 1 213 ? 64.171 42.465 32.893 1.00 95.77 ? 213 MET K CB 1 +ATOM 20598 C CG . MET K 1 213 ? 64.414 41.472 31.789 1.00 119.34 ? 213 MET K CG 1 +ATOM 20599 S SD . MET K 1 213 ? 63.798 42.274 30.273 1.00 132.00 ? 213 MET K SD 1 +ATOM 20600 C CE . MET K 1 213 ? 65.412 42.480 29.517 1.00 184.19 ? 213 MET K CE 1 +ATOM 20601 N N . LEU K 1 214 ? 66.843 42.893 34.202 1.00 89.58 ? 214 LEU K N 1 +ATOM 20602 C CA . LEU K 1 214 ? 68.283 42.805 33.988 1.00 119.53 ? 214 LEU K CA 1 +ATOM 20603 C C . LEU K 1 214 ? 69.002 42.738 35.329 1.00 136.83 ? 214 LEU K C 1 +ATOM 20604 O O . LEU K 1 214 ? 70.067 42.125 35.454 1.00 165.82 ? 214 LEU K O 1 +ATOM 20605 C CB . LEU K 1 214 ? 68.768 44.027 33.196 1.00 145.00 ? 214 LEU K CB 1 +ATOM 20606 C CG . LEU K 1 214 ? 69.781 43.833 32.061 1.00 159.37 ? 214 LEU K CG 1 +ATOM 20607 C CD1 . LEU K 1 214 ? 69.244 42.895 30.977 1.00 180.47 ? 214 LEU K CD1 1 +ATOM 20608 C CD2 . LEU K 1 214 ? 70.151 45.186 31.462 1.00 134.01 ? 214 LEU K CD2 1 +ATOM 20609 N N . CYS K 1 215 ? 68.398 43.352 36.341 1.00 121.98 ? 215 CYS K N 1 +ATOM 20610 C CA . CYS K 1 215 ? 68.917 43.282 37.710 1.00 112.56 ? 215 CYS K CA 1 +ATOM 20611 C C . CYS K 1 215 ? 68.740 41.879 38.312 1.00 102.89 ? 215 CYS K C 1 +ATOM 20612 O O . CYS K 1 215 ? 69.625 41.352 39.016 1.00 66.99 ? 215 CYS K O 1 +ATOM 20613 C CB . CYS K 1 215 ? 68.186 44.281 38.597 1.00 117.92 ? 215 CYS K CB 1 +ATOM 20614 S SG . CYS K 1 215 ? 68.450 45.988 38.120 1.00 127.15 ? 215 CYS K SG 1 +ATOM 20615 N N . LEU K 1 216 ? 67.573 41.293 38.046 1.00 98.74 ? 216 LEU K N 1 +ATOM 20616 C CA . LEU K 1 216 ? 67.315 39.925 38.431 1.00 92.36 ? 216 LEU K CA 1 +ATOM 20617 C C . LEU K 1 216 ? 68.384 39.015 37.826 1.00 86.46 ? 216 LEU K C 1 +ATOM 20618 O O . LEU K 1 216 ? 69.000 38.210 38.544 1.00 110.11 ? 216 LEU K O 1 +ATOM 20619 C CB . LEU K 1 216 ? 65.921 39.486 37.985 1.00 73.41 ? 216 LEU K CB 1 +ATOM 20620 C CG . LEU K 1 216 ? 65.584 38.024 38.316 1.00 64.48 ? 216 LEU K CG 1 +ATOM 20621 C CD1 . LEU K 1 216 ? 65.664 37.720 39.797 1.00 60.83 ? 216 LEU K CD1 1 +ATOM 20622 C CD2 . LEU K 1 216 ? 64.183 37.713 37.823 1.00 91.59 ? 216 LEU K CD2 1 +ATOM 20623 N N . MET K 1 217 ? 68.657 39.211 36.538 1.00 67.45 ? 217 MET K N 1 +ATOM 20624 C CA . MET K 1 217 ? 69.581 38.350 35.833 1.00 86.99 ? 217 MET K CA 1 +ATOM 20625 C C . MET K 1 217 ? 70.986 38.495 36.414 1.00 112.15 ? 217 MET K C 1 +ATOM 20626 O O . MET K 1 217 ? 71.641 37.494 36.746 1.00 181.67 ? 217 MET K O 1 +ATOM 20627 C CB . MET K 1 217 ? 69.588 38.655 34.343 1.00 87.75 ? 217 MET K CB 1 +ATOM 20628 C CG . MET K 1 217 ? 69.602 37.396 33.469 1.00 87.07 ? 217 MET K CG 1 +ATOM 20629 S SD . MET K 1 217 ? 71.175 36.505 33.559 1.00 137.24 ? 217 MET K SD 1 +ATOM 20630 C CE . MET K 1 217 ? 70.802 34.982 32.688 1.00 89.66 ? 217 MET K CE 1 +ATOM 20631 N N . SER K 1 218 ? 71.404 39.735 36.631 1.00 107.01 ? 218 SER K N 1 +ATOM 20632 C CA . SER K 1 218 ? 72.703 40.027 37.256 1.00 101.56 ? 218 SER K CA 1 +ATOM 20633 C C . SER K 1 218 ? 72.880 39.340 38.612 1.00 90.25 ? 218 SER K C 1 +ATOM 20634 O O . SER K 1 218 ? 73.879 38.674 38.866 1.00 60.65 ? 218 SER K O 1 +ATOM 20635 C CB . SER K 1 218 ? 72.858 41.543 37.440 1.00 111.06 ? 218 SER K CB 1 +ATOM 20636 O OG . SER K 1 218 ? 74.181 41.890 37.802 1.00 97.56 ? 218 SER K OG 1 +ATOM 20637 N N . ALA K 1 219 ? 71.890 39.518 39.479 1.00 96.80 ? 219 ALA K N 1 +ATOM 20638 C CA . ALA K 1 219 ? 71.967 38.990 40.824 1.00 101.25 ? 219 ALA K CA 1 +ATOM 20639 C C . ALA K 1 219 ? 72.054 37.452 40.820 1.00 89.66 ? 219 ALA K C 1 +ATOM 20640 O O . ALA K 1 219 ? 72.695 36.841 41.686 1.00 74.98 ? 219 ALA K O 1 +ATOM 20641 C CB . ALA K 1 219 ? 70.767 39.485 41.630 1.00 115.14 ? 219 ALA K CB 1 +ATOM 20642 N N . ILE K 1 220 ? 71.345 36.822 39.889 1.00 79.70 ? 220 ILE K N 1 +ATOM 20643 C CA . ILE K 1 220 ? 71.349 35.361 39.801 1.00 80.81 ? 220 ILE K CA 1 +ATOM 20644 C C . ILE K 1 220 ? 72.738 34.855 39.386 1.00 83.93 ? 220 ILE K C 1 +ATOM 20645 O O . ILE K 1 220 ? 73.239 33.875 39.940 1.00 68.01 ? 220 ILE K O 1 +ATOM 20646 C CB . ILE K 1 220 ? 70.263 34.833 38.825 1.00 73.26 ? 220 ILE K CB 1 +ATOM 20647 C CG1 . ILE K 1 220 ? 68.857 35.079 39.416 1.00 64.68 ? 220 ILE K CG1 1 +ATOM 20648 C CG2 . ILE K 1 220 ? 70.497 33.342 38.509 1.00 58.63 ? 220 ILE K CG2 1 +ATOM 20649 C CD1 . ILE K 1 220 ? 67.730 34.981 38.419 1.00 49.55 ? 220 ILE K CD1 1 +ATOM 20650 N N . GLU K 1 221 ? 73.366 35.556 38.445 1.00 99.29 ? 221 GLU K N 1 +ATOM 20651 C CA . GLU K 1 221 ? 74.729 35.232 38.030 1.00 110.01 ? 221 GLU K CA 1 +ATOM 20652 C C . GLU K 1 221 ? 75.670 35.299 39.243 1.00 132.51 ? 221 GLU K C 1 +ATOM 20653 O O . GLU K 1 221 ? 76.422 34.347 39.516 1.00 128.60 ? 221 GLU K O 1 +ATOM 20654 C CB . GLU K 1 221 ? 75.195 36.201 36.938 1.00 98.88 ? 221 GLU K CB 1 +ATOM 20655 C CG . GLU K 1 221 ? 74.563 35.938 35.586 1.00 92.18 ? 221 GLU K CG 1 +ATOM 20656 C CD . GLU K 1 221 ? 74.668 37.111 34.624 1.00 101.48 ? 221 GLU K CD 1 +ATOM 20657 O OE1 . GLU K 1 221 ? 74.608 38.299 35.056 1.00 118.81 ? 221 GLU K OE1 1 +ATOM 20658 O OE2 . GLU K 1 221 ? 74.831 36.835 33.412 1.00 83.52 ? 221 GLU K OE2 1 +ATOM 20659 N N . THR K 1 222 ? 75.599 36.419 39.970 1.00 115.99 ? 222 THR K N 1 +ATOM 20660 C CA . THR K 1 222 ? 76.397 36.647 41.177 1.00 85.96 ? 222 THR K CA 1 +ATOM 20661 C C . THR K 1 222 ? 76.227 35.503 42.170 1.00 84.02 ? 222 THR K C 1 +ATOM 20662 O O . THR K 1 222 ? 77.212 34.967 42.692 1.00 69.55 ? 222 THR K O 1 +ATOM 20663 C CB . THR K 1 222 ? 75.952 37.946 41.856 1.00 79.64 ? 222 THR K CB 1 +ATOM 20664 O OG1 . THR K 1 222 ? 76.382 39.082 41.084 1.00 85.57 ? 222 THR K OG1 1 +ATOM 20665 C CG2 . THR K 1 222 ? 76.490 38.027 43.299 1.00 86.00 ? 222 THR K CG2 1 +ATOM 20666 N N . GLY K 1 223 ? 74.970 35.134 42.415 1.00 73.30 ? 223 GLY K N 1 +ATOM 20667 C CA . GLY K 1 223 ? 74.655 33.978 43.244 1.00 75.97 ? 223 GLY K CA 1 +ATOM 20668 C C . GLY K 1 223 ? 75.308 32.672 42.784 1.00 78.01 ? 223 GLY K C 1 +ATOM 20669 O O . GLY K 1 223 ? 75.812 31.894 43.607 1.00 79.81 ? 223 GLY K O 1 +ATOM 20670 N N . VAL K 1 224 ? 75.331 32.441 41.474 1.00 72.01 ? 224 VAL K N 1 +ATOM 20671 C CA . VAL K 1 224 ? 75.952 31.242 40.940 1.00 83.49 ? 224 VAL K CA 1 +ATOM 20672 C C . VAL K 1 224 ? 77.451 31.242 41.235 1.00 95.89 ? 224 VAL K C 1 +ATOM 20673 O O . VAL K 1 224 ? 78.007 30.207 41.627 1.00 121.01 ? 224 VAL K O 1 +ATOM 20674 C CB . VAL K 1 224 ? 75.751 31.121 39.428 1.00 109.43 ? 224 VAL K CB 1 +ATOM 20675 C CG1 . VAL K 1 224 ? 76.554 29.947 38.872 1.00 108.90 ? 224 VAL K CG1 1 +ATOM 20676 C CG2 . VAL K 1 224 ? 74.277 30.964 39.103 1.00 117.49 ? 224 VAL K CG2 1 +ATOM 20677 N N . ILE K 1 225 ? 78.098 32.396 41.080 1.00 82.45 ? 225 ILE K N 1 +ATOM 20678 C CA . ILE K 1 225 ? 79.514 32.497 41.398 1.00 82.12 ? 225 ILE K CA 1 +ATOM 20679 C C . ILE K 1 225 ? 79.751 32.146 42.863 1.00 88.74 ? 225 ILE K C 1 +ATOM 20680 O O . ILE K 1 225 ? 80.602 31.298 43.163 1.00 62.58 ? 225 ILE K O 1 +ATOM 20681 C CB . ILE K 1 225 ? 80.078 33.895 41.093 1.00 94.54 ? 225 ILE K CB 1 +ATOM 20682 C CG1 . ILE K 1 225 ? 80.088 34.126 39.585 1.00 125.78 ? 225 ILE K CG1 1 +ATOM 20683 C CG2 . ILE K 1 225 ? 81.501 34.031 41.620 1.00 84.48 ? 225 ILE K CG2 1 +ATOM 20684 C CD1 . ILE K 1 225 ? 80.218 35.583 39.190 1.00 161.40 ? 225 ILE K CD1 1 +ATOM 20685 N N . PHE K 1 226 ? 79.021 32.810 43.774 1.00 89.25 ? 226 PHE K N 1 +ATOM 20686 C CA . PHE K 1 226 ? 79.158 32.551 45.229 1.00 88.31 ? 226 PHE K CA 1 +ATOM 20687 C C . PHE K 1 226 ? 78.937 31.060 45.574 1.00 77.81 ? 226 PHE K C 1 +ATOM 20688 O O . PHE K 1 226 ? 79.574 30.528 46.471 1.00 55.86 ? 226 PHE K O 1 +ATOM 20689 C CB . PHE K 1 226 ? 78.186 33.415 46.057 1.00 85.05 ? 226 PHE K CB 1 +ATOM 20690 C CG . PHE K 1 226 ? 78.632 34.839 46.284 1.00 97.70 ? 226 PHE K CG 1 +ATOM 20691 C CD1 . PHE K 1 226 ? 79.849 35.119 46.921 1.00 131.12 ? 226 PHE K CD1 1 +ATOM 20692 C CD2 . PHE K 1 226 ? 77.805 35.901 45.952 1.00 91.26 ? 226 PHE K CD2 1 +ATOM 20693 C CE1 . PHE K 1 226 ? 80.278 36.434 47.125 1.00 95.91 ? 226 PHE K CE1 1 +ATOM 20694 C CE2 . PHE K 1 226 ? 78.215 37.209 46.178 1.00 101.80 ? 226 PHE K CE2 1 +ATOM 20695 C CZ . PHE K 1 226 ? 79.459 37.473 46.761 1.00 95.27 ? 226 PHE K CZ 1 +ATOM 20696 N N . LEU K 1 227 ? 78.033 30.412 44.852 1.00 71.24 ? 227 LEU K N 1 +ATOM 20697 C CA . LEU K 1 227 ? 77.800 28.991 45.017 1.00 74.62 ? 227 LEU K CA 1 +ATOM 20698 C C . LEU K 1 227 ? 79.001 28.157 44.593 1.00 80.68 ? 227 LEU K C 1 +ATOM 20699 O O . LEU K 1 227 ? 79.387 27.237 45.294 1.00 67.10 ? 227 LEU K O 1 +ATOM 20700 C CB . LEU K 1 227 ? 76.584 28.591 44.199 1.00 94.19 ? 227 LEU K CB 1 +ATOM 20701 C CG . LEU K 1 227 ? 75.217 28.966 44.787 1.00 95.78 ? 227 LEU K CG 1 +ATOM 20702 C CD1 . LEU K 1 227 ? 74.035 28.822 43.839 1.00 81.27 ? 227 LEU K CD1 1 +ATOM 20703 C CD2 . LEU K 1 227 ? 74.949 28.174 46.053 1.00 109.92 ? 227 LEU K CD2 1 +ATOM 20704 N N . ILE K 1 228 ? 79.615 28.507 43.463 1.00 96.25 ? 228 ILE K N 1 +ATOM 20705 C CA . ILE K 1 228 ? 80.763 27.759 42.959 1.00 106.05 ? 228 ILE K CA 1 +ATOM 20706 C C . ILE K 1 228 ? 81.922 27.939 43.916 1.00 106.13 ? 228 ILE K C 1 +ATOM 20707 O O . ILE K 1 228 ? 82.586 26.963 44.297 1.00 107.44 ? 228 ILE K O 1 +ATOM 20708 C CB . ILE K 1 228 ? 81.214 28.217 41.548 1.00 107.91 ? 228 ILE K CB 1 +ATOM 20709 C CG1 . ILE K 1 228 ? 80.131 27.926 40.512 1.00 114.55 ? 228 ILE K CG1 1 +ATOM 20710 C CG2 . ILE K 1 228 ? 82.473 27.474 41.127 1.00 98.85 ? 228 ILE K CG2 1 +ATOM 20711 C CD1 . ILE K 1 228 ? 80.309 28.646 39.196 1.00 97.42 ? 228 ILE K CD1 1 +ATOM 20712 N N . ASN K 1 229 ? 82.170 29.187 44.301 1.00 77.54 ? 229 ASN K N 1 +ATOM 20713 C CA . ASN K 1 229 ? 83.275 29.488 45.195 1.00 91.43 ? 229 ASN K CA 1 +ATOM 20714 C C . ASN K 1 229 ? 83.089 28.740 46.518 1.00 76.89 ? 229 ASN K C 1 +ATOM 20715 O O . ASN K 1 229 ? 84.043 28.169 47.069 1.00 85.38 ? 229 ASN K O 1 +ATOM 20716 C CB . ASN K 1 229 ? 83.371 31.015 45.408 1.00 110.22 ? 229 ASN K CB 1 +ATOM 20717 C CG . ASN K 1 229 ? 84.719 31.473 45.968 1.00 124.14 ? 229 ASN K CG 1 +ATOM 20718 O OD1 . ASN K 1 229 ? 85.717 30.750 45.891 1.00 158.19 ? 229 ASN K OD1 1 +ATOM 20719 N ND2 . ASN K 1 229 ? 84.730 32.655 46.589 1.00 96.53 ? 229 ASN K ND2 1 +ATOM 20720 N N . ASP K 1 230 ? 81.874 28.790 47.040 1.00 56.20 ? 230 ASP K N 1 +ATOM 20721 C CA . ASP K 1 230 ? 81.576 28.139 48.285 1.00 63.62 ? 230 ASP K CA 1 +ATOM 20722 C C . ASP K 1 230 ? 81.857 26.649 48.155 1.00 69.48 ? 230 ASP K C 1 +ATOM 20723 O O . ASP K 1 230 ? 82.320 25.990 49.086 1.00 67.12 ? 230 ASP K O 1 +ATOM 20724 C CB . ASP K 1 230 ? 80.119 28.395 48.658 1.00 84.08 ? 230 ASP K CB 1 +ATOM 20725 C CG . ASP K 1 230 ? 79.757 27.821 50.024 1.00 115.16 ? 230 ASP K CG 1 +ATOM 20726 O OD1 . ASP K 1 230 ? 80.175 28.419 51.033 1.00 133.62 ? 230 ASP K OD1 1 +ATOM 20727 O OD2 . ASP K 1 230 ? 78.999 26.819 50.090 1.00 189.02 ? 230 ASP K OD2 1 +ATOM 20728 N N . GLY K 1 231 ? 81.462 26.082 47.025 1.00 108.26 ? 231 GLY K N 1 +ATOM 20729 C CA . GLY K 1 231 ? 81.601 24.644 46.808 1.00 128.20 ? 231 GLY K CA 1 +ATOM 20730 C C . GLY K 1 231 ? 83.071 24.275 46.728 1.00 107.48 ? 231 GLY K C 1 +ATOM 20731 O O . GLY K 1 231 ? 83.458 23.158 47.114 1.00 98.81 ? 231 GLY K O 1 +ATOM 20732 N N . ILE K 1 232 ? 83.869 25.190 46.171 1.00 78.33 ? 232 ILE K N 1 +ATOM 20733 C CA . ILE K 1 232 ? 85.295 24.961 46.047 1.00 100.46 ? 232 ILE K CA 1 +ATOM 20734 C C . ILE K 1 232 ? 85.869 24.857 47.449 1.00 122.70 ? 232 ILE K C 1 +ATOM 20735 O O . ILE K 1 232 ? 86.624 23.922 47.743 1.00 129.27 ? 232 ILE K O 1 +ATOM 20736 C CB . ILE K 1 232 ? 85.990 26.092 45.256 1.00 115.30 ? 232 ILE K CB 1 +ATOM 20737 C CG1 . ILE K 1 232 ? 85.690 25.943 43.763 1.00 121.80 ? 232 ILE K CG1 1 +ATOM 20738 C CG2 . ILE K 1 232 ? 87.508 26.098 45.496 1.00 137.33 ? 232 ILE K CG2 1 +ATOM 20739 C CD1 . ILE K 1 232 ? 85.949 27.197 42.951 1.00 123.24 ? 232 ILE K CD1 1 +ATOM 20740 N N . ASP K 1 233 ? 85.530 25.830 48.296 1.00 137.08 ? 233 ASP K N 1 +ATOM 20741 C CA . ASP K 1 233 ? 85.989 25.855 49.690 1.00 149.59 ? 233 ASP K CA 1 +ATOM 20742 C C . ASP K 1 233 ? 85.595 24.583 50.435 1.00 142.55 ? 233 ASP K C 1 +ATOM 20743 O O . ASP K 1 233 ? 86.432 23.942 51.068 1.00 176.09 ? 233 ASP K O 1 +ATOM 20744 C CB . ASP K 1 233 ? 85.405 27.062 50.432 1.00 150.88 ? 233 ASP K CB 1 +ATOM 20745 C CG . ASP K 1 233 ? 85.912 28.404 49.896 1.00 151.27 ? 233 ASP K CG 1 +ATOM 20746 O OD1 . ASP K 1 233 ? 86.575 28.424 48.836 1.00 139.05 ? 233 ASP K OD1 1 +ATOM 20747 O OD2 . ASP K 1 233 ? 85.636 29.442 50.546 1.00 129.43 ? 233 ASP K OD2 1 +ATOM 20748 N N . ARG K 1 234 ? 84.334 24.200 50.311 1.00 138.25 ? 234 ARG K N 1 +ATOM 20749 C CA . ARG K 1 234 ? 83.810 23.066 51.052 1.00 156.87 ? 234 ARG K CA 1 +ATOM 20750 C C . ARG K 1 234 ? 84.129 21.685 50.455 1.00 178.28 ? 234 ARG K C 1 +ATOM 20751 O O . ARG K 1 234 ? 83.740 20.650 51.018 1.00 240.88 ? 234 ARG K O 1 +ATOM 20752 C CB . ARG K 1 234 ? 82.304 23.227 51.211 1.00 172.86 ? 234 ARG K CB 1 +ATOM 20753 C CG . ARG K 1 234 ? 81.968 24.325 52.194 1.00 156.31 ? 234 ARG K CG 1 +ATOM 20754 C CD . ARG K 1 234 ? 80.568 24.866 52.005 1.00 162.33 ? 234 ARG K CD 1 +ATOM 20755 N NE . ARG K 1 234 ? 80.386 25.968 52.946 1.00 148.37 ? 234 ARG K NE 1 +ATOM 20756 C CZ . ARG K 1 234 ? 79.442 26.018 53.876 1.00 164.26 ? 234 ARG K CZ 1 +ATOM 20757 N NH1 . ARG K 1 234 ? 78.518 25.052 53.928 1.00 207.56 ? 234 ARG K NH1 1 +ATOM 20758 N NH2 . ARG K 1 234 ? 79.405 27.030 54.745 1.00 107.74 ? 234 ARG K NH2 1 +ATOM 20759 N N . GLY K 1 235 ? 84.823 21.658 49.324 1.00 167.26 ? 235 GLY K N 1 +ATOM 20760 C CA . GLY K 1 235 ? 85.246 20.399 48.716 1.00 140.19 ? 235 GLY K CA 1 +ATOM 20761 C C . GLY K 1 235 ? 84.135 19.648 48.008 1.00 97.08 ? 235 GLY K C 1 +ATOM 20762 O O . GLY K 1 235 ? 84.143 18.419 47.974 1.00 56.83 ? 235 GLY K O 1 +ATOM 20763 N N . LEU K 1 236 ? 83.179 20.384 47.440 1.00 98.07 ? 236 LEU K N 1 +ATOM 20764 C CA . LEU K 1 236 ? 82.194 19.767 46.547 1.00 118.18 ? 236 LEU K CA 1 +ATOM 20765 C C . LEU K 1 236 ? 82.884 19.448 45.227 1.00 110.86 ? 236 LEU K C 1 +ATOM 20766 O O . LEU K 1 236 ? 82.741 18.338 44.697 1.00 141.17 ? 236 LEU K O 1 +ATOM 20767 C CB . LEU K 1 236 ? 80.970 20.677 46.295 1.00 122.44 ? 236 LEU K CB 1 +ATOM 20768 C CG . LEU K 1 236 ? 79.846 20.671 47.332 1.00 108.67 ? 236 LEU K CG 1 +ATOM 20769 C CD1 . LEU K 1 236 ? 80.211 21.514 48.549 1.00 109.57 ? 236 LEU K CD1 1 +ATOM 20770 C CD2 . LEU K 1 236 ? 78.564 21.190 46.712 1.00 94.76 ? 236 LEU K CD2 1 +ATOM 20771 N N . TRP K 1 237 ? 83.612 20.426 44.693 1.00 81.73 ? 237 TRP K N 1 +ATOM 20772 C CA . TRP K 1 237 ? 84.255 20.282 43.390 1.00 88.33 ? 237 TRP K CA 1 +ATOM 20773 C C . TRP K 1 237 ? 85.623 20.938 43.419 1.00 108.74 ? 237 TRP K C 1 +ATOM 20774 O O . TRP K 1 237 ? 85.932 21.693 44.343 1.00 106.11 ? 237 TRP K O 1 +ATOM 20775 C CB . TRP K 1 237 ? 83.389 20.878 42.275 1.00 84.96 ? 237 TRP K CB 1 +ATOM 20776 C CG . TRP K 1 237 ? 82.599 22.054 42.713 1.00 97.02 ? 237 TRP K CG 1 +ATOM 20777 C CD1 . TRP K 1 237 ? 83.085 23.276 43.048 1.00 110.25 ? 237 TRP K CD1 1 +ATOM 20778 C CD2 . TRP K 1 237 ? 81.169 22.135 42.863 1.00 121.44 ? 237 TRP K CD2 1 +ATOM 20779 N NE1 . TRP K 1 237 ? 82.054 24.129 43.380 1.00 106.24 ? 237 TRP K NE1 1 +ATOM 20780 C CE2 . TRP K 1 237 ? 80.868 23.457 43.272 1.00 121.07 ? 237 TRP K CE2 1 +ATOM 20781 C CE3 . TRP K 1 237 ? 80.119 21.224 42.693 1.00 127.56 ? 237 TRP K CE3 1 +ATOM 20782 C CZ2 . TRP K 1 237 ? 79.567 23.887 43.523 1.00 133.53 ? 237 TRP K CZ2 1 +ATOM 20783 C CZ3 . TRP K 1 237 ? 78.823 21.653 42.948 1.00 136.45 ? 237 TRP K CZ3 1 +ATOM 20784 C CH2 . TRP K 1 237 ? 78.562 22.975 43.355 1.00 153.49 ? 237 TRP K CH2 1 +ATOM 20785 N N . ASP K 1 238 ? 86.456 20.606 42.434 1.00 131.61 ? 238 ASP K N 1 +ATOM 20786 C CA . ASP K 1 238 ? 87.864 21.008 42.444 1.00 135.33 ? 238 ASP K CA 1 +ATOM 20787 C C . ASP K 1 238 ? 88.294 21.675 41.147 1.00 128.31 ? 238 ASP K C 1 +ATOM 20788 O O . ASP K 1 238 ? 87.822 21.323 40.055 1.00 112.81 ? 238 ASP K O 1 +ATOM 20789 C CB . ASP K 1 238 ? 88.781 19.811 42.721 1.00 123.52 ? 238 ASP K CB 1 +ATOM 20790 C CG . ASP K 1 238 ? 88.449 19.108 44.023 1.00 122.41 ? 238 ASP K CG 1 +ATOM 20791 O OD1 . ASP K 1 238 ? 87.485 18.315 44.025 1.00 99.42 ? 238 ASP K OD1 1 +ATOM 20792 O OD2 . ASP K 1 238 ? 89.134 19.351 45.045 1.00 113.35 ? 238 ASP K OD2 1 +ATOM 20793 N N . LEU K 1 239 ? 89.236 22.608 41.274 1.00 126.25 ? 239 LEU K N 1 +ATOM 20794 C CA . LEU K 1 239 ? 89.760 23.340 40.130 1.00 137.98 ? 239 LEU K CA 1 +ATOM 20795 C C . LEU K 1 239 ? 90.730 22.475 39.328 1.00 140.48 ? 239 LEU K C 1 +ATOM 20796 O O . LEU K 1 239 ? 91.471 21.672 39.891 1.00 102.09 ? 239 LEU K O 1 +ATOM 20797 C CB . LEU K 1 239 ? 90.474 24.622 40.584 1.00 129.26 ? 239 LEU K CB 1 +ATOM 20798 C CG . LEU K 1 239 ? 89.654 25.835 41.020 1.00 126.10 ? 239 LEU K CG 1 +ATOM 20799 C CD1 . LEU K 1 239 ? 90.560 27.021 41.324 1.00 138.21 ? 239 LEU K CD1 1 +ATOM 20800 C CD2 . LEU K 1 239 ? 88.652 26.215 39.950 1.00 143.36 ? 239 LEU K CD2 1 +ATOM 20801 N N . GLN K 1 240 ? 90.705 22.653 38.009 1.00 143.36 ? 240 GLN K N 1 +ATOM 20802 C CA . GLN K 1 240 ? 91.709 22.070 37.138 1.00 129.49 ? 240 GLN K CA 1 +ATOM 20803 C C . GLN K 1 240 ? 93.106 22.459 37.626 1.00 133.90 ? 240 GLN K C 1 +ATOM 20804 O O . GLN K 1 240 ? 93.947 21.600 37.900 1.00 129.52 ? 240 GLN K O 1 +ATOM 20805 C CB . GLN K 1 240 ? 91.494 22.539 35.688 1.00 125.64 ? 240 GLN K CB 1 +ATOM 20806 C CG . GLN K 1 240 ? 92.375 21.825 34.669 1.00 125.77 ? 240 GLN K CG 1 +ATOM 20807 C CD . GLN K 1 240 ? 92.050 20.345 34.570 1.00 134.73 ? 240 GLN K CD 1 +ATOM 20808 O OE1 . GLN K 1 240 ? 91.085 19.954 33.910 1.00 145.27 ? 240 GLN K OE1 1 +ATOM 20809 N NE2 . GLN K 1 240 ? 92.822 19.515 35.271 1.00 136.97 ? 240 GLN K NE2 1 +ATOM 20810 N N . ASN K 1 241 ? 93.338 23.766 37.716 1.00 151.94 ? 241 ASN K N 1 +ATOM 20811 C CA . ASN K 1 241 ? 94.612 24.319 38.166 1.00 153.12 ? 241 ASN K CA 1 +ATOM 20812 C C . ASN K 1 241 ? 94.502 24.847 39.583 1.00 134.51 ? 241 ASN K C 1 +ATOM 20813 O O . ASN K 1 241 ? 93.869 25.881 39.819 1.00 111.23 ? 241 ASN K O 1 +ATOM 20814 C CB . ASN K 1 241 ? 95.043 25.463 37.248 1.00 166.41 ? 241 ASN K CB 1 +ATOM 20815 C CG . ASN K 1 241 ? 96.089 25.037 36.244 1.00 197.03 ? 241 ASN K CG 1 +ATOM 20816 O OD1 . ASN K 1 241 ? 97.271 25.319 36.426 1.00 187.68 ? 241 ASN K OD1 1 +ATOM 20817 N ND2 . ASN K 1 241 ? 95.666 24.341 35.187 1.00 217.43 ? 241 ASN K ND2 1 +ATOM 20818 N N . LYS K 1 242 ? 95.146 24.150 40.516 1.00 125.81 ? 242 LYS K N 1 +ATOM 20819 C CA . LYS K 1 242 ? 95.128 24.556 41.917 1.00 109.65 ? 242 LYS K CA 1 +ATOM 20820 C C . LYS K 1 242 ? 95.828 25.904 42.074 1.00 125.88 ? 242 LYS K C 1 +ATOM 20821 O O . LYS K 1 242 ? 95.518 26.678 42.988 1.00 90.22 ? 242 LYS K O 1 +ATOM 20822 C CB . LYS K 1 242 ? 95.786 23.487 42.790 1.00 110.62 ? 242 LYS K CB 1 +ATOM 20823 C CG . LYS K 1 242 ? 95.280 22.075 42.519 1.00 120.72 ? 242 LYS K CG 1 +ATOM 20824 C CD . LYS K 1 242 ? 94.780 21.398 43.784 1.00 148.31 ? 242 LYS K CD 1 +ATOM 20825 C CE . LYS K 1 242 ? 93.433 20.728 43.552 1.00 166.62 ? 242 LYS K CE 1 +ATOM 20826 N NZ . LYS K 1 242 ? 92.982 19.925 44.722 1.00 170.51 ? 242 LYS K NZ 1 +ATOM 20827 N N . ALA K 1 243 ? 96.741 26.179 41.134 1.00 159.15 ? 243 ALA K N 1 +ATOM 20828 C CA . ALA K 1 243 ? 97.432 27.463 41.024 1.00 160.48 ? 243 ALA K CA 1 +ATOM 20829 C C . ALA K 1 243 ? 96.460 28.604 40.747 1.00 176.13 ? 243 ALA K C 1 +ATOM 20830 O O . ALA K 1 243 ? 96.797 29.773 40.967 1.00 175.84 ? 243 ALA K O 1 +ATOM 20831 C CB . ALA K 1 243 ? 98.485 27.404 39.920 1.00 142.53 ? 243 ALA K CB 1 +ATOM 20832 N N . GLU K 1 244 ? 95.266 28.274 40.248 1.00 177.08 ? 244 GLU K N 1 +ATOM 20833 C CA . GLU K 1 244 ? 94.285 29.302 39.913 1.00 173.38 ? 244 GLU K CA 1 +ATOM 20834 C C . GLU K 1 244 ? 93.326 29.599 41.063 1.00 159.04 ? 244 GLU K C 1 +ATOM 20835 O O . GLU K 1 244 ? 92.345 30.298 40.862 1.00 140.74 ? 244 GLU K O 1 +ATOM 20836 C CB . GLU K 1 244 ? 93.492 28.912 38.665 1.00 150.74 ? 244 GLU K CB 1 +ATOM 20837 C CG . GLU K 1 244 ? 94.283 29.010 37.377 1.00 152.41 ? 244 GLU K CG 1 +ATOM 20838 C CD . GLU K 1 244 ? 93.405 28.878 36.148 1.00 164.04 ? 244 GLU K CD 1 +ATOM 20839 O OE1 . GLU K 1 244 ? 93.015 27.737 35.809 1.00 164.38 ? 244 GLU K OE1 1 +ATOM 20840 O OE2 . GLU K 1 244 ? 93.140 29.913 35.494 1.00 174.14 ? 244 GLU K OE2 1 +ATOM 20841 N N . ARG K 1 245 ? 93.620 29.091 42.258 1.00 139.22 ? 245 ARG K N 1 +ATOM 20842 C CA . ARG K 1 245 ? 92.838 29.438 43.435 1.00 131.66 ? 245 ARG K CA 1 +ATOM 20843 C C . ARG K 1 245 ? 92.785 30.947 43.677 1.00 134.85 ? 245 ARG K C 1 +ATOM 20844 O O . ARG K 1 245 ? 91.766 31.457 44.159 1.00 173.38 ? 245 ARG K O 1 +ATOM 20845 C CB . ARG K 1 245 ? 93.365 28.753 44.688 1.00 139.04 ? 245 ARG K CB 1 +ATOM 20846 C CG . ARG K 1 245 ? 92.459 28.939 45.908 1.00 143.49 ? 245 ARG K CG 1 +ATOM 20847 C CD . ARG K 1 245 ? 92.941 28.160 47.138 1.00 180.04 ? 245 ARG K CD 1 +ATOM 20848 N NE . ARG K 1 245 ? 92.226 26.887 47.267 1.00 228.43 ? 245 ARG K NE 1 +ATOM 20849 C CZ . ARG K 1 245 ? 90.951 26.763 47.635 1.00 213.02 ? 245 ARG K CZ 1 +ATOM 20850 N NH1 . ARG K 1 245 ? 90.221 27.830 47.888 1.00 176.49 ? 245 ARG K NH1 1 +ATOM 20851 N NH2 . ARG K 1 245 ? 90.399 25.559 47.747 1.00 219.98 ? 245 ARG K NH2 1 +ATOM 20852 N N . GLN K 1 246 ? 93.889 31.650 43.412 1.00 113.56 ? 246 GLN K N 1 +ATOM 20853 C CA . GLN K 1 246 ? 93.963 33.082 43.725 1.00 116.99 ? 246 GLN K CA 1 +ATOM 20854 C C . GLN K 1 246 ? 93.553 33.925 42.533 1.00 110.05 ? 246 GLN K C 1 +ATOM 20855 O O . GLN K 1 246 ? 93.929 35.093 42.427 1.00 114.97 ? 246 GLN K O 1 +ATOM 20856 C CB . GLN K 1 246 ? 95.364 33.481 44.212 1.00 125.45 ? 246 GLN K CB 1 +ATOM 20857 C CG . GLN K 1 246 ? 95.711 32.984 45.608 1.00 153.95 ? 246 GLN K CG 1 +ATOM 20858 C CD . GLN K 1 246 ? 96.032 31.504 45.624 1.00 186.23 ? 246 GLN K CD 1 +ATOM 20859 O OE1 . GLN K 1 246 ? 96.784 31.013 44.777 1.00 188.04 ? 246 GLN K OE1 1 +ATOM 20860 N NE2 . GLN K 1 246 ? 95.502 30.792 46.615 1.00 216.77 ? 246 GLN K NE2 1 +ATOM 20861 N N . ASN K 1 247 ? 92.800 33.314 41.622 1.00 111.89 ? 247 ASN K N 1 +ATOM 20862 C CA . ASN K 1 247 ? 92.144 34.027 40.520 1.00 117.92 ? 247 ASN K CA 1 +ATOM 20863 C C . ASN K 1 247 ? 91.526 35.337 41.004 1.00 112.94 ? 247 ASN K C 1 +ATOM 20864 O O . ASN K 1 247 ? 90.906 35.374 42.073 1.00 129.26 ? 247 ASN K O 1 +ATOM 20865 C CB . ASN K 1 247 ? 91.054 33.128 39.928 1.00 122.10 ? 247 ASN K CB 1 +ATOM 20866 C CG . ASN K 1 247 ? 90.740 33.454 38.494 1.00 134.39 ? 247 ASN K CG 1 +ATOM 20867 O OD1 . ASN K 1 247 ? 89.680 34.012 38.187 1.00 137.90 ? 247 ASN K OD1 1 +ATOM 20868 N ND2 . ASN K 1 247 ? 91.666 33.120 37.602 1.00 140.97 ? 247 ASN K ND2 1 +ATOM 20869 N N . ASP K 1 248 ? 91.669 36.395 40.211 1.00 120.36 ? 248 ASP K N 1 +ATOM 20870 C CA . ASP K 1 248 ? 91.151 37.727 40.580 1.00 150.19 ? 248 ASP K CA 1 +ATOM 20871 C C . ASP K 1 248 ? 89.671 37.681 40.976 1.00 153.85 ? 248 ASP K C 1 +ATOM 20872 O O . ASP K 1 248 ? 89.251 38.270 41.983 1.00 133.95 ? 248 ASP K O 1 +ATOM 20873 C CB . ASP K 1 248 ? 91.312 38.709 39.410 1.00 166.07 ? 248 ASP K CB 1 +ATOM 20874 C CG . ASP K 1 248 ? 92.762 39.091 39.152 1.00 169.27 ? 248 ASP K CG 1 +ATOM 20875 O OD1 . ASP K 1 248 ? 93.524 39.275 40.121 1.00 141.16 ? 248 ASP K OD1 1 +ATOM 20876 O OD2 . ASP K 1 248 ? 93.123 39.251 37.969 1.00 199.84 ? 248 ASP K OD2 1 +ATOM 20877 N N . ILE K 1 249 ? 88.884 36.993 40.153 1.00 164.45 ? 249 ILE K N 1 +ATOM 20878 C CA . ILE K 1 249 ? 87.443 36.914 40.338 1.00 150.29 ? 249 ILE K CA 1 +ATOM 20879 C C . ILE K 1 249 ? 87.121 36.131 41.616 1.00 140.28 ? 249 ILE K C 1 +ATOM 20880 O O . ILE K 1 249 ? 86.368 36.600 42.478 1.00 184.38 ? 249 ILE K O 1 +ATOM 20881 C CB . ILE K 1 249 ? 86.774 36.245 39.119 1.00 142.25 ? 249 ILE K CB 1 +ATOM 20882 C CG1 . ILE K 1 249 ? 86.994 37.088 37.855 1.00 133.24 ? 249 ILE K CG1 1 +ATOM 20883 C CG2 . ILE K 1 249 ? 85.287 36.075 39.363 1.00 154.34 ? 249 ILE K CG2 1 +ATOM 20884 C CD1 . ILE K 1 249 ? 86.817 36.321 36.563 1.00 125.62 ? 249 ILE K CD1 1 +ATOM 20885 N N . LEU K 1 250 ? 87.732 34.957 41.749 1.00 112.40 ? 250 LEU K N 1 +ATOM 20886 C CA . LEU K 1 250 ? 87.506 34.094 42.912 1.00 108.44 ? 250 LEU K CA 1 +ATOM 20887 C C . LEU K 1 250 ? 87.860 34.761 44.244 1.00 126.04 ? 250 LEU K C 1 +ATOM 20888 O O . LEU K 1 250 ? 87.154 34.577 45.236 1.00 155.51 ? 250 LEU K O 1 +ATOM 20889 C CB . LEU K 1 250 ? 88.291 32.793 42.777 1.00 106.68 ? 250 LEU K CB 1 +ATOM 20890 C CG . LEU K 1 250 ? 87.662 31.751 41.853 1.00 109.82 ? 250 LEU K CG 1 +ATOM 20891 C CD1 . LEU K 1 250 ? 88.626 30.619 41.536 1.00 104.28 ? 250 LEU K CD1 1 +ATOM 20892 C CD2 . LEU K 1 250 ? 86.400 31.200 42.480 1.00 118.23 ? 250 LEU K CD2 1 +ATOM 20893 N N . VAL K 1 251 ? 88.945 35.534 44.264 1.00 131.05 ? 251 VAL K N 1 +ATOM 20894 C CA . VAL K 1 251 ? 89.338 36.253 45.477 1.00 135.69 ? 251 VAL K CA 1 +ATOM 20895 C C . VAL K 1 251 ? 88.457 37.485 45.724 1.00 146.25 ? 251 VAL K C 1 +ATOM 20896 O O . VAL K 1 251 ? 88.321 37.945 46.864 1.00 178.38 ? 251 VAL K O 1 +ATOM 20897 C CB . VAL K 1 251 ? 90.822 36.675 45.454 1.00 140.92 ? 251 VAL K CB 1 +ATOM 20898 C CG1 . VAL K 1 251 ? 91.712 35.464 45.207 1.00 133.37 ? 251 VAL K CG1 1 +ATOM 20899 C CG2 . VAL K 1 251 ? 91.079 37.776 44.424 1.00 133.27 ? 251 VAL K CG2 1 +ATOM 20900 N N . LYS K 1 252 ? 87.876 38.027 44.656 1.00 125.04 ? 252 LYS K N 1 +ATOM 20901 C CA . LYS K 1 252 ? 86.948 39.151 44.774 1.00 107.30 ? 252 LYS K CA 1 +ATOM 20902 C C . LYS K 1 252 ? 85.663 38.707 45.494 1.00 124.41 ? 252 LYS K C 1 +ATOM 20903 O O . LYS K 1 252 ? 85.205 39.365 46.436 1.00 143.42 ? 252 LYS K O 1 +ATOM 20904 C CB . LYS K 1 252 ? 86.653 39.702 43.384 1.00 103.68 ? 252 LYS K CB 1 +ATOM 20905 C CG . LYS K 1 252 ? 85.672 40.854 43.340 1.00 113.15 ? 252 LYS K CG 1 +ATOM 20906 C CD . LYS K 1 252 ? 85.438 41.286 41.890 1.00 133.43 ? 252 LYS K CD 1 +ATOM 20907 C CE . LYS K 1 252 ? 83.952 41.454 41.571 1.00 140.01 ? 252 LYS K CE 1 +ATOM 20908 N NZ . LYS K 1 252 ? 83.673 41.620 40.111 1.00 107.86 ? 252 LYS K NZ 1 +ATOM 20909 N N . TYR K 1 253 ? 85.126 37.550 45.096 1.00 151.57 ? 253 TYR K N 1 +ATOM 20910 C CA . TYR K 1 253 ? 83.883 37.003 45.689 1.00 134.01 ? 253 TYR K CA 1 +ATOM 20911 C C . TYR K 1 253 ? 84.156 36.348 47.032 1.00 124.17 ? 253 TYR K C 1 +ATOM 20912 O O . TYR K 1 253 ? 83.329 36.401 47.935 1.00 130.98 ? 253 TYR K O 1 +ATOM 20913 C CB . TYR K 1 253 ? 83.206 36.001 44.738 1.00 113.90 ? 253 TYR K CB 1 +ATOM 20914 C CG . TYR K 1 253 ? 82.564 36.667 43.541 1.00 110.72 ? 253 TYR K CG 1 +ATOM 20915 C CD1 . TYR K 1 253 ? 81.309 37.247 43.635 1.00 106.95 ? 253 TYR K CD1 1 +ATOM 20916 C CD2 . TYR K 1 253 ? 83.264 36.827 42.346 1.00 123.24 ? 253 TYR K CD2 1 +ATOM 20917 C CE1 . TYR K 1 253 ? 80.749 37.920 42.558 1.00 109.58 ? 253 TYR K CE1 1 +ATOM 20918 C CE2 . TYR K 1 253 ? 82.716 37.524 41.275 1.00 131.62 ? 253 TYR K CE2 1 +ATOM 20919 C CZ . TYR K 1 253 ? 81.446 38.058 41.388 1.00 116.76 ? 253 TYR K CZ 1 +ATOM 20920 O OH . TYR K 1 253 ? 80.899 38.760 40.327 1.00 112.49 ? 253 TYR K OH 1 +ATOM 20921 N N . ARG K 1 254 ? 85.348 35.778 47.173 1.00 115.51 ? 254 ARG K N 1 +ATOM 20922 C CA . ARG K 1 254 ? 85.837 35.340 48.476 1.00 106.05 ? 254 ARG K CA 1 +ATOM 20923 C C . ARG K 1 254 ? 85.834 36.513 49.462 1.00 98.49 ? 254 ARG K C 1 +ATOM 20924 O O . ARG K 1 254 ? 85.512 36.350 50.643 1.00 93.04 ? 254 ARG K O 1 +ATOM 20925 C CB . ARG K 1 254 ? 87.257 34.751 48.358 1.00 109.31 ? 254 ARG K CB 1 +ATOM 20926 C CG . ARG K 1 254 ? 87.779 34.148 49.649 1.00 98.30 ? 254 ARG K CG 1 +ATOM 20927 C CD . ARG K 1 254 ? 88.957 33.219 49.433 1.00 94.49 ? 254 ARG K CD 1 +ATOM 20928 N NE . ARG K 1 254 ? 88.610 32.021 48.682 1.00 99.00 ? 254 ARG K NE 1 +ATOM 20929 C CZ . ARG K 1 254 ? 88.975 31.774 47.429 1.00 142.21 ? 254 ARG K CZ 1 +ATOM 20930 N NH1 . ARG K 1 254 ? 89.702 32.647 46.741 1.00 142.60 ? 254 ARG K NH1 1 +ATOM 20931 N NH2 . ARG K 1 254 ? 88.616 30.629 46.852 1.00 166.93 ? 254 ARG K NH2 1 +ATOM 20932 N N . HIS K 1 255 ? 86.261 37.679 48.986 1.00 110.26 ? 255 HIS K N 1 +ATOM 20933 C CA . HIS K 1 255 ? 86.355 38.874 49.825 1.00 138.79 ? 255 HIS K CA 1 +ATOM 20934 C C . HIS K 1 255 ? 84.982 39.383 50.240 1.00 130.22 ? 255 HIS K C 1 +ATOM 20935 O O . HIS K 1 255 ? 84.825 39.933 51.329 1.00 162.61 ? 255 HIS K O 1 +ATOM 20936 C CB . HIS K 1 255 ? 87.164 39.985 49.117 1.00 156.10 ? 255 HIS K CB 1 +ATOM 20937 C CG . HIS K 1 255 ? 88.533 40.188 49.686 1.00 155.79 ? 255 HIS K CG 1 +ATOM 20938 N ND1 . HIS K 1 255 ? 89.568 39.298 49.478 1.00 141.80 ? 255 HIS K ND1 1 +ATOM 20939 C CD2 . HIS K 1 255 ? 89.029 41.165 50.482 1.00 168.23 ? 255 HIS K CD2 1 +ATOM 20940 C CE1 . HIS K 1 255 ? 90.646 39.729 50.109 1.00 165.49 ? 255 HIS K CE1 1 +ATOM 20941 N NE2 . HIS K 1 255 ? 90.345 40.859 50.727 1.00 184.99 ? 255 HIS K NE2 1 +ATOM 20942 N N . MET K 1 256 ? 83.999 39.249 49.355 1.00 121.34 ? 256 MET K N 1 +ATOM 20943 C CA . MET K 1 256 ? 82.654 39.732 49.669 1.00 128.45 ? 256 MET K CA 1 +ATOM 20944 C C . MET K 1 256 ? 82.014 38.886 50.784 1.00 144.23 ? 256 MET K C 1 +ATOM 20945 O O . MET K 1 256 ? 81.136 39.367 51.504 1.00 121.91 ? 256 MET K O 1 +ATOM 20946 C CB . MET K 1 256 ? 81.786 39.762 48.405 1.00 123.70 ? 256 MET K CB 1 +ATOM 20947 C CG . MET K 1 256 ? 82.398 40.555 47.248 1.00 115.53 ? 256 MET K CG 1 +ATOM 20948 S SD . MET K 1 256 ? 81.254 41.086 45.952 1.00 107.11 ? 256 MET K SD 1 +ATOM 20949 C CE . MET K 1 256 ? 80.282 42.309 46.859 1.00 89.49 ? 256 MET K CE 1 +ATOM 20950 N N . SER K 1 257 ? 82.506 37.654 50.955 1.00 161.74 ? 257 SER K N 1 +ATOM 20951 C CA . SER K 1 257 ? 82.073 36.758 52.043 1.00 147.09 ? 257 SER K CA 1 +ATOM 20952 C C . SER K 1 257 ? 82.704 37.145 53.382 1.00 123.32 ? 257 SER K C 1 +ATOM 20953 O O . SER K 1 257 ? 82.129 37.937 54.122 1.00 99.18 ? 257 SER K O 1 +ATOM 20954 C CB . SER K 1 257 ? 82.428 35.296 51.718 1.00 134.96 ? 257 SER K CB 1 +ATOM 20955 O OG . SER K 1 257 ? 82.136 34.976 50.368 1.00 118.05 ? 257 SER K OG 1 +ATOM 20956 N N . LEU L 1 2 ? 70.889 56.148 21.773 1.00 129.91 ? 2 LEU L N 1 +ATOM 20957 C CA . LEU L 1 2 ? 70.405 56.218 23.183 1.00 110.92 ? 2 LEU L CA 1 +ATOM 20958 C C . LEU L 1 2 ? 68.868 56.061 23.214 1.00 108.19 ? 2 LEU L C 1 +ATOM 20959 O O . LEU L 1 2 ? 68.109 57.004 23.539 1.00 67.44 ? 2 LEU L O 1 +ATOM 20960 C CB . LEU L 1 2 ? 70.853 57.519 23.861 1.00 118.04 ? 2 LEU L CB 1 +ATOM 20961 C CG . LEU L 1 2 ? 72.371 57.787 24.013 1.00 137.42 ? 2 LEU L CG 1 +ATOM 20962 C CD1 . LEU L 1 2 ? 72.577 59.145 24.688 1.00 149.76 ? 2 LEU L CD1 1 +ATOM 20963 C CD2 . LEU L 1 2 ? 73.153 56.702 24.768 1.00 121.88 ? 2 LEU L CD2 1 +ATOM 20964 N N . THR L 1 3 ? 68.452 54.863 22.787 1.00 111.42 ? 3 THR L N 1 +ATOM 20965 C CA . THR L 1 3 ? 67.131 54.284 23.048 1.00 120.33 ? 3 THR L CA 1 +ATOM 20966 C C . THR L 1 3 ? 67.221 52.738 23.290 1.00 159.02 ? 3 THR L C 1 +ATOM 20967 O O . THR L 1 3 ? 66.209 52.077 23.576 1.00 156.27 ? 3 THR L O 1 +ATOM 20968 C CB . THR L 1 3 ? 66.168 54.494 21.873 1.00 91.13 ? 3 THR L CB 1 +ATOM 20969 O OG1 . THR L 1 3 ? 66.609 53.693 20.753 1.00 151.45 ? 3 THR L OG1 1 +ATOM 20970 C CG2 . THR L 1 3 ? 66.069 55.960 21.502 1.00 79.06 ? 3 THR L CG2 1 +ATOM 20971 N N . ALA L 1 4 ? 68.415 52.164 23.142 1.00 162.15 ? 4 ALA L N 1 +ATOM 20972 C CA . ALA L 1 4 ? 68.696 50.808 23.643 1.00 144.07 ? 4 ALA L CA 1 +ATOM 20973 C C . ALA L 1 4 ? 68.839 50.835 25.187 1.00 148.08 ? 4 ALA L C 1 +ATOM 20974 O O . ALA L 1 4 ? 68.628 51.877 25.814 1.00 149.09 ? 4 ALA L O 1 +ATOM 20975 C CB . ALA L 1 4 ? 69.950 50.246 22.982 1.00 140.90 ? 4 ALA L CB 1 +ATOM 20976 N N . PRO L 1 5 ? 69.170 49.696 25.826 1.00 136.21 ? 5 PRO L N 1 +ATOM 20977 C CA . PRO L 1 5 ? 68.886 49.766 27.264 1.00 137.82 ? 5 PRO L CA 1 +ATOM 20978 C C . PRO L 1 5 ? 69.997 50.434 28.040 1.00 142.41 ? 5 PRO L C 1 +ATOM 20979 O O . PRO L 1 5 ? 71.077 50.677 27.483 1.00 167.15 ? 5 PRO L O 1 +ATOM 20980 C CB . PRO L 1 5 ? 68.766 48.299 27.668 1.00 142.37 ? 5 PRO L CB 1 +ATOM 20981 C CG . PRO L 1 5 ? 69.586 47.538 26.657 1.00 136.03 ? 5 PRO L CG 1 +ATOM 20982 C CD . PRO L 1 5 ? 69.745 48.396 25.428 1.00 110.51 ? 5 PRO L CD 1 +ATOM 20983 N N . PRO L 1 6 ? 69.736 50.752 29.314 1.00 142.41 ? 6 PRO L N 1 +ATOM 20984 C CA . PRO L 1 6 ? 70.823 51.111 30.241 1.00 158.70 ? 6 PRO L CA 1 +ATOM 20985 C C . PRO L 1 6 ? 71.567 49.913 30.864 1.00 145.90 ? 6 PRO L C 1 +ATOM 20986 O O . PRO L 1 6 ? 71.014 48.825 30.966 1.00 102.71 ? 6 PRO L O 1 +ATOM 20987 C CB . PRO L 1 6 ? 70.115 51.893 31.341 1.00 135.32 ? 6 PRO L CB 1 +ATOM 20988 C CG . PRO L 1 6 ? 68.673 51.541 31.235 1.00 127.89 ? 6 PRO L CG 1 +ATOM 20989 C CD . PRO L 1 6 ? 68.397 50.954 29.885 1.00 111.45 ? 6 PRO L CD 1 +ATOM 20990 N N . LYS L 1 7 ? 72.836 50.115 31.215 1.00 144.26 ? 7 LYS L N 1 +ATOM 20991 C CA . LYS L 1 7 ? 73.642 49.093 31.911 1.00 141.62 ? 7 LYS L CA 1 +ATOM 20992 C C . LYS L 1 7 ? 73.710 49.410 33.395 1.00 131.76 ? 7 LYS L C 1 +ATOM 20993 O O . LYS L 1 7 ? 73.224 50.449 33.842 1.00 79.08 ? 7 LYS L O 1 +ATOM 20994 C CB . LYS L 1 7 ? 75.069 48.994 31.348 1.00 133.75 ? 7 LYS L CB 1 +ATOM 20995 C CG . LYS L 1 7 ? 75.170 48.362 29.975 1.00 125.30 ? 7 LYS L CG 1 +ATOM 20996 C CD . LYS L 1 7 ? 75.378 49.375 28.849 1.00 112.39 ? 7 LYS L CD 1 +ATOM 20997 C CE . LYS L 1 7 ? 75.757 48.664 27.559 1.00 97.00 ? 7 LYS L CE 1 +ATOM 20998 N NZ . LYS L 1 7 ? 75.304 49.420 26.361 1.00 98.76 ? 7 LYS L NZ 1 +ATOM 20999 N N . GLU L 1 8 ? 74.248 48.463 34.162 1.00 143.65 ? 8 GLU L N 1 +ATOM 21000 C CA . GLU L 1 8 ? 74.000 48.393 35.606 1.00 136.35 ? 8 GLU L CA 1 +ATOM 21001 C C . GLU L 1 8 ? 74.589 49.522 36.392 1.00 109.58 ? 8 GLU L C 1 +ATOM 21002 O O . GLU L 1 8 ? 75.789 49.694 36.421 1.00 101.07 ? 8 GLU L O 1 +ATOM 21003 C CB . GLU L 1 8 ? 74.488 47.089 36.201 1.00 136.77 ? 8 GLU L CB 1 +ATOM 21004 C CG . GLU L 1 8 ? 73.292 46.382 36.857 1.00 152.37 ? 8 GLU L CG 1 +ATOM 21005 C CD . GLU L 1 8 ? 72.806 45.136 36.113 1.00 166.74 ? 8 GLU L CD 1 +ATOM 21006 O OE1 . GLU L 1 8 ? 72.783 45.178 34.854 1.00 244.70 ? 8 GLU L OE1 1 +ATOM 21007 O OE2 . GLU L 1 8 ? 72.379 44.144 36.773 1.00 128.34 ? 8 GLU L OE2 1 +ATOM 21008 N N . ALA L 1 9 ? 73.708 50.276 37.034 1.00 118.68 ? 9 ALA L N 1 +ATOM 21009 C CA . ALA L 1 9 ? 74.082 51.273 38.005 1.00 120.21 ? 9 ALA L CA 1 +ATOM 21010 C C . ALA L 1 9 ? 73.963 50.660 39.411 1.00 97.00 ? 9 ALA L C 1 +ATOM 21011 O O . ALA L 1 9 ? 72.861 50.423 39.909 1.00 71.52 ? 9 ALA L O 1 +ATOM 21012 C CB . ALA L 1 9 ? 73.183 52.496 37.855 1.00 119.52 ? 9 ALA L CB 1 +ATOM 21013 N N . ALA L 1 10 ? 75.118 50.479 40.051 1.00 84.63 ? 10 ALA L N 1 +ATOM 21014 C CA . ALA L 1 10 ? 75.270 49.781 41.333 1.00 72.47 ? 10 ALA L CA 1 +ATOM 21015 C C . ALA L 1 10 ? 75.412 48.317 41.075 1.00 64.53 ? 10 ALA L C 1 +ATOM 21016 O O . ALA L 1 10 ? 74.968 47.806 40.035 1.00 78.27 ? 10 ALA L O 1 +ATOM 21017 C CB . ALA L 1 10 ? 74.133 50.082 42.318 1.00 74.18 ? 10 ALA L CB 1 +ATOM 21018 N N . ARG L 1 11 ? 76.048 47.636 42.012 1.00 63.35 ? 11 ARG L N 1 +ATOM 21019 C CA . ARG L 1 11 ? 76.482 46.256 41.790 1.00 99.36 ? 11 ARG L CA 1 +ATOM 21020 C C . ARG L 1 11 ? 75.595 45.248 42.552 1.00 97.31 ? 11 ARG L C 1 +ATOM 21021 O O . ARG L 1 11 ? 75.090 45.564 43.629 1.00 115.51 ? 11 ARG L O 1 +ATOM 21022 C CB . ARG L 1 11 ? 77.913 46.117 42.304 1.00 140.26 ? 11 ARG L CB 1 +ATOM 21023 C CG . ARG L 1 11 ? 77.883 46.234 43.835 1.00 164.87 ? 11 ARG L CG 1 +ATOM 21024 C CD . ARG L 1 11 ? 78.823 47.237 44.416 1.00 161.26 ? 11 ARG L CD 1 +ATOM 21025 N NE . ARG L 1 11 ? 78.083 47.979 45.449 1.00 144.41 ? 11 ARG L NE 1 +ATOM 21026 C CZ . ARG L 1 11 ? 77.201 48.984 45.289 1.00 111.73 ? 11 ARG L CZ 1 +ATOM 21027 N NH1 . ARG L 1 11 ? 76.988 49.585 44.119 1.00 84.80 ? 11 ARG L NH1 1 +ATOM 21028 N NH2 . ARG L 1 11 ? 76.569 49.448 46.366 1.00 109.27 ? 11 ARG L NH2 1 +ATOM 21029 N N . PRO L 1 12 ? 75.502 43.996 42.065 1.00 89.20 ? 12 PRO L N 1 +ATOM 21030 C CA . PRO L 1 12 ? 74.973 42.950 42.921 1.00 89.53 ? 12 PRO L CA 1 +ATOM 21031 C C . PRO L 1 12 ? 75.897 42.666 44.108 1.00 116.30 ? 12 PRO L C 1 +ATOM 21032 O O . PRO L 1 12 ? 77.050 42.249 43.932 1.00 111.52 ? 12 PRO L O 1 +ATOM 21033 C CB . PRO L 1 12 ? 74.910 41.731 42.003 1.00 91.34 ? 12 PRO L CB 1 +ATOM 21034 C CG . PRO L 1 12 ? 75.138 42.240 40.629 1.00 107.17 ? 12 PRO L CG 1 +ATOM 21035 C CD . PRO L 1 12 ? 75.974 43.463 40.782 1.00 100.76 ? 12 PRO L CD 1 +ATOM 21036 N N . THR L 1 13 ? 75.410 42.972 45.308 1.00 118.37 ? 13 THR L N 1 +ATOM 21037 C CA . THR L 1 13 ? 76.045 42.522 46.542 1.00 109.64 ? 13 THR L CA 1 +ATOM 21038 C C . THR L 1 13 ? 75.334 41.275 47.091 1.00 90.33 ? 13 THR L C 1 +ATOM 21039 O O . THR L 1 13 ? 74.204 41.008 46.714 1.00 69.95 ? 13 THR L O 1 +ATOM 21040 C CB . THR L 1 13 ? 75.973 43.622 47.599 1.00 111.60 ? 13 THR L CB 1 +ATOM 21041 O OG1 . THR L 1 13 ? 76.803 43.253 48.709 1.00 152.61 ? 13 THR L OG1 1 +ATOM 21042 C CG2 . THR L 1 13 ? 74.502 43.893 48.052 1.00 88.20 ? 13 THR L CG2 1 +ATOM 21043 N N . LEU L 1 14 ? 75.970 40.518 47.982 1.00 84.34 ? 14 LEU L N 1 +ATOM 21044 C CA . LEU L 1 14 ? 75.211 39.471 48.697 1.00 79.23 ? 14 LEU L CA 1 +ATOM 21045 C C . LEU L 1 14 ? 74.396 40.152 49.806 1.00 66.02 ? 14 LEU L C 1 +ATOM 21046 O O . LEU L 1 14 ? 74.613 41.312 50.074 1.00 56.30 ? 14 LEU L O 1 +ATOM 21047 C CB . LEU L 1 14 ? 76.080 38.319 49.205 1.00 74.96 ? 14 LEU L CB 1 +ATOM 21048 C CG . LEU L 1 14 ? 77.284 38.662 50.042 1.00 86.53 ? 14 LEU L CG 1 +ATOM 21049 C CD1 . LEU L 1 14 ? 77.527 37.575 51.072 1.00 97.95 ? 14 LEU L CD1 1 +ATOM 21050 C CD2 . LEU L 1 14 ? 78.493 38.795 49.152 1.00 89.96 ? 14 LEU L CD2 1 +ATOM 21051 N N . MET L 1 15 ? 73.331 39.521 50.284 1.00 73.67 ? 15 MET L N 1 +ATOM 21052 C CA . MET L 1 15 ? 72.172 40.277 50.806 1.00 84.33 ? 15 MET L CA 1 +ATOM 21053 C C . MET L 1 15 ? 72.531 40.944 52.135 1.00 92.04 ? 15 MET L C 1 +ATOM 21054 O O . MET L 1 15 ? 72.980 40.269 53.064 1.00 125.29 ? 15 MET L O 1 +ATOM 21055 C CB . MET L 1 15 ? 70.935 39.381 50.973 1.00 90.88 ? 15 MET L CB 1 +ATOM 21056 C CG . MET L 1 15 ? 69.635 40.161 50.857 1.00 102.30 ? 15 MET L CG 1 +ATOM 21057 S SD . MET L 1 15 ? 68.236 39.793 51.914 1.00 140.95 ? 15 MET L SD 1 +ATOM 21058 C CE . MET L 1 15 ? 68.855 38.741 53.225 1.00 124.03 ? 15 MET L CE 1 +ATOM 21059 N N . PRO L 1 16 ? 72.355 42.277 52.220 1.00 81.05 ? 16 PRO L N 1 +ATOM 21060 C CA . PRO L 1 16 ? 72.805 43.085 53.339 1.00 88.92 ? 16 PRO L CA 1 +ATOM 21061 C C . PRO L 1 16 ? 72.104 42.739 54.667 1.00 98.29 ? 16 PRO L C 1 +ATOM 21062 O O . PRO L 1 16 ? 71.226 43.475 55.115 1.00 109.70 ? 16 PRO L O 1 +ATOM 21063 C CB . PRO L 1 16 ? 72.470 44.518 52.887 1.00 79.72 ? 16 PRO L CB 1 +ATOM 21064 C CG . PRO L 1 16 ? 71.376 44.361 51.914 1.00 66.61 ? 16 PRO L CG 1 +ATOM 21065 C CD . PRO L 1 16 ? 71.701 43.098 51.193 1.00 72.38 ? 16 PRO L CD 1 +ATOM 21066 N N . ARG L 1 17 ? 72.625 41.724 55.354 1.00 84.89 ? 17 ARG L N 1 +ATOM 21067 C CA . ARG L 1 17 ? 72.230 41.420 56.730 1.00 81.78 ? 17 ARG L CA 1 +ATOM 21068 C C . ARG L 1 17 ? 73.100 42.150 57.754 1.00 74.92 ? 17 ARG L C 1 +ATOM 21069 O O . ARG L 1 17 ? 74.244 42.456 57.469 1.00 58.40 ? 17 ARG L O 1 +ATOM 21070 C CB . ARG L 1 17 ? 72.347 39.935 56.970 1.00 79.28 ? 17 ARG L CB 1 +ATOM 21071 C CG . ARG L 1 17 ? 71.114 39.145 56.530 1.00 84.46 ? 17 ARG L CG 1 +ATOM 21072 C CD . ARG L 1 17 ? 71.371 37.649 56.380 1.00 71.56 ? 17 ARG L CD 1 +ATOM 21073 N NE . ARG L 1 17 ? 71.993 37.343 55.098 1.00 93.07 ? 17 ARG L NE 1 +ATOM 21074 C CZ . ARG L 1 17 ? 72.548 36.176 54.801 1.00 112.94 ? 17 ARG L CZ 1 +ATOM 21075 N NH1 . ARG L 1 17 ? 72.459 35.188 55.675 1.00 102.62 ? 17 ARG L NH1 1 +ATOM 21076 N NH2 . ARG L 1 17 ? 73.180 35.989 53.628 1.00 131.55 ? 17 ARG L NH2 1 +ATOM 21077 N N . ALA L 1 18 ? 72.494 42.590 58.859 1.00 87.47 ? 18 ALA L N 1 +ATOM 21078 C CA . ALA L 1 18 ? 73.191 43.455 59.822 1.00 105.89 ? 18 ALA L CA 1 +ATOM 21079 C C . ALA L 1 18 ? 73.444 42.757 61.159 1.00 121.66 ? 18 ALA L C 1 +ATOM 21080 O O . ALA L 1 18 ? 74.146 41.741 61.193 1.00 169.48 ? 18 ALA L O 1 +ATOM 21081 C CB . ALA L 1 18 ? 72.463 44.782 60.034 1.00 109.77 ? 18 ALA L CB 1 +ATOM 21082 N N . GLN L 1 19 ? 72.904 43.301 62.254 1.00 98.35 ? 19 GLN L N 1 +ATOM 21083 C CA . GLN L 1 19 ? 73.396 42.962 63.594 1.00 88.36 ? 19 GLN L CA 1 +ATOM 21084 C C . GLN L 1 19 ? 73.050 41.526 64.000 1.00 78.85 ? 19 GLN L C 1 +ATOM 21085 O O . GLN L 1 19 ? 73.907 40.755 64.458 1.00 63.28 ? 19 GLN L O 1 +ATOM 21086 C CB . GLN L 1 19 ? 72.832 43.941 64.625 1.00 93.58 ? 19 GLN L CB 1 +ATOM 21087 C CG . GLN L 1 19 ? 73.405 43.776 66.030 1.00 119.52 ? 19 GLN L CG 1 +ATOM 21088 C CD . GLN L 1 19 ? 74.926 43.850 66.072 1.00 127.11 ? 19 GLN L CD 1 +ATOM 21089 O OE1 . GLN L 1 19 ? 75.515 44.892 65.783 1.00 112.38 ? 19 GLN L OE1 1 +ATOM 21090 N NE2 . GLN L 1 19 ? 75.567 42.724 66.390 1.00 122.67 ? 19 GLN L NE2 1 +ATOM 21091 N N . SER L 1 20 ? 71.773 41.193 63.837 1.00 95.02 ? 20 SER L N 1 +ATOM 21092 C CA . SER L 1 20 ? 71.250 39.834 64.029 1.00 90.27 ? 20 SER L CA 1 +ATOM 21093 C C . SER L 1 20 ? 72.159 38.768 63.398 1.00 77.58 ? 20 SER L C 1 +ATOM 21094 O O . SER L 1 20 ? 72.603 37.841 64.078 1.00 69.26 ? 20 SER L O 1 +ATOM 21095 C CB . SER L 1 20 ? 69.840 39.742 63.424 1.00 72.80 ? 20 SER L CB 1 +ATOM 21096 O OG . SER L 1 20 ? 69.028 40.805 63.906 1.00 58.46 ? 20 SER L OG 1 +ATOM 21097 N N . TYR L 1 21 ? 72.511 38.988 62.137 1.00 70.20 ? 21 TYR L N 1 +ATOM 21098 C CA . TYR L 1 21 ? 73.474 38.151 61.445 1.00 75.66 ? 21 TYR L CA 1 +ATOM 21099 C C . TYR L 1 21 ? 74.815 38.012 62.187 1.00 75.91 ? 21 TYR L C 1 +ATOM 21100 O O . TYR L 1 21 ? 75.344 36.895 62.342 1.00 54.83 ? 21 TYR L O 1 +ATOM 21101 C CB . TYR L 1 21 ? 73.722 38.696 60.033 1.00 86.54 ? 21 TYR L CB 1 +ATOM 21102 C CG . TYR L 1 21 ? 74.645 37.823 59.210 1.00 106.59 ? 21 TYR L CG 1 +ATOM 21103 C CD1 . TYR L 1 21 ? 74.188 36.633 58.649 1.00 118.08 ? 21 TYR L CD1 1 +ATOM 21104 C CD2 . TYR L 1 21 ? 75.972 38.175 58.996 1.00 113.52 ? 21 TYR L CD2 1 +ATOM 21105 C CE1 . TYR L 1 21 ? 75.023 35.825 57.903 1.00 124.61 ? 21 TYR L CE1 1 +ATOM 21106 C CE2 . TYR L 1 21 ? 76.811 37.369 58.239 1.00 121.37 ? 21 TYR L CE2 1 +ATOM 21107 C CZ . TYR L 1 21 ? 76.323 36.197 57.695 1.00 121.42 ? 21 TYR L CZ 1 +ATOM 21108 O OH . TYR L 1 21 ? 77.113 35.390 56.909 1.00 186.31 ? 21 TYR L OH 1 +ATOM 21109 N N . LYS L 1 22 ? 75.407 39.153 62.566 1.00 88.39 ? 22 LYS L N 1 +ATOM 21110 C CA . LYS L 1 22 ? 76.743 39.183 63.183 1.00 82.73 ? 22 LYS L CA 1 +ATOM 21111 C C . LYS L 1 22 ? 76.766 38.420 64.487 1.00 78.79 ? 22 LYS L C 1 +ATOM 21112 O O . LYS L 1 22 ? 77.709 37.671 64.767 1.00 75.88 ? 22 LYS L O 1 +ATOM 21113 C CB . LYS L 1 22 ? 77.183 40.614 63.431 1.00 87.68 ? 22 LYS L CB 1 +ATOM 21114 C CG . LYS L 1 22 ? 77.937 41.228 62.269 1.00 123.57 ? 22 LYS L CG 1 +ATOM 21115 C CD . LYS L 1 22 ? 79.416 40.799 62.297 1.00 152.63 ? 22 LYS L CD 1 +ATOM 21116 C CE . LYS L 1 22 ? 80.286 41.933 62.859 1.00 175.31 ? 22 LYS L CE 1 +ATOM 21117 N NZ . LYS L 1 22 ? 80.279 43.124 61.965 1.00 184.79 ? 22 LYS L NZ 1 +ATOM 21118 N N . ASP L 1 23 ? 75.687 38.565 65.248 1.00 87.79 ? 23 ASP L N 1 +ATOM 21119 C CA . ASP L 1 23 ? 75.481 37.762 66.453 1.00 96.36 ? 23 ASP L CA 1 +ATOM 21120 C C . ASP L 1 23 ? 75.336 36.274 66.129 1.00 107.18 ? 23 ASP L C 1 +ATOM 21121 O O . ASP L 1 23 ? 75.953 35.418 66.782 1.00 136.86 ? 23 ASP L O 1 +ATOM 21122 C CB . ASP L 1 23 ? 74.238 38.240 67.207 1.00 73.41 ? 23 ASP L CB 1 +ATOM 21123 C CG . ASP L 1 23 ? 74.404 39.624 67.743 1.00 72.68 ? 23 ASP L CG 1 +ATOM 21124 O OD1 . ASP L 1 23 ? 75.496 39.902 68.289 1.00 83.00 ? 23 ASP L OD1 1 +ATOM 21125 O OD2 . ASP L 1 23 ? 73.433 40.404 67.696 1.00 69.88 ? 23 ASP L OD2 1 +ATOM 21126 N N . LEU L 1 24 ? 74.513 35.983 65.125 1.00 95.39 ? 24 LEU L N 1 +ATOM 21127 C CA . LEU L 1 24 ? 74.163 34.611 64.764 1.00 102.48 ? 24 LEU L CA 1 +ATOM 21128 C C . LEU L 1 24 ? 75.379 33.807 64.269 1.00 105.87 ? 24 LEU L C 1 +ATOM 21129 O O . LEU L 1 24 ? 75.492 32.592 64.539 1.00 81.18 ? 24 LEU L O 1 +ATOM 21130 C CB . LEU L 1 24 ? 73.080 34.630 63.689 1.00 92.75 ? 24 LEU L CB 1 +ATOM 21131 C CG . LEU L 1 24 ? 72.562 33.278 63.178 1.00 89.38 ? 24 LEU L CG 1 +ATOM 21132 C CD1 . LEU L 1 24 ? 71.439 32.759 64.049 1.00 82.91 ? 24 LEU L CD1 1 +ATOM 21133 C CD2 . LEU L 1 24 ? 72.090 33.421 61.738 1.00 107.27 ? 24 LEU L CD2 1 +ATOM 21134 N N . THR L 1 25 ? 76.292 34.493 63.578 1.00 108.11 ? 25 THR L N 1 +ATOM 21135 C CA . THR L 1 25 ? 77.469 33.839 63.002 1.00 126.23 ? 25 THR L CA 1 +ATOM 21136 C C . THR L 1 25 ? 78.534 33.553 64.047 1.00 137.36 ? 25 THR L C 1 +ATOM 21137 O O . THR L 1 25 ? 79.059 32.426 64.117 1.00 135.43 ? 25 THR L O 1 +ATOM 21138 C CB . THR L 1 25 ? 78.099 34.691 61.885 1.00 123.25 ? 25 THR L CB 1 +ATOM 21139 O OG1 . THR L 1 25 ? 78.199 36.052 62.310 1.00 92.25 ? 25 THR L OG1 1 +ATOM 21140 C CG2 . THR L 1 25 ? 77.244 34.612 60.624 1.00 131.22 ? 25 THR L CG2 1 +ATOM 21141 N N . HIS L 1 26 ? 78.817 34.558 64.879 1.00 132.14 ? 26 HIS L N 1 +ATOM 21142 C CA . HIS L 1 26 ? 79.834 34.453 65.925 1.00 129.31 ? 26 HIS L CA 1 +ATOM 21143 C C . HIS L 1 26 ? 79.272 33.798 67.206 1.00 119.63 ? 26 HIS L C 1 +ATOM 21144 O O . HIS L 1 26 ? 79.667 34.138 68.306 1.00 108.24 ? 26 HIS L O 1 +ATOM 21145 C CB . HIS L 1 26 ? 80.425 35.840 66.231 1.00 115.27 ? 26 HIS L CB 1 +ATOM 21146 C CG . HIS L 1 26 ? 81.149 36.449 65.071 1.00 130.95 ? 26 HIS L CG 1 +ATOM 21147 N ND1 . HIS L 1 26 ? 80.493 36.888 63.942 1.00 163.78 ? 26 HIS L ND1 1 +ATOM 21148 C CD2 . HIS L 1 26 ? 82.471 36.623 64.828 1.00 127.73 ? 26 HIS L CD2 1 +ATOM 21149 C CE1 . HIS L 1 26 ? 81.376 37.339 63.068 1.00 175.17 ? 26 HIS L CE1 1 +ATOM 21150 N NE2 . HIS L 1 26 ? 82.585 37.178 63.577 1.00 154.71 ? 26 HIS L NE2 1 +ATOM 21151 N N . LEU L 1 27 ? 78.396 32.810 67.048 1.00 125.32 ? 27 LEU L N 1 +ATOM 21152 C CA . LEU L 1 27 ? 77.920 32.019 68.178 1.00 105.05 ? 27 LEU L CA 1 +ATOM 21153 C C . LEU L 1 27 ? 78.851 30.842 68.417 1.00 102.00 ? 27 LEU L C 1 +ATOM 21154 O O . LEU L 1 27 ? 79.240 30.146 67.472 1.00 127.88 ? 27 LEU L O 1 +ATOM 21155 C CB . LEU L 1 27 ? 76.501 31.501 67.927 1.00 102.45 ? 27 LEU L CB 1 +ATOM 21156 C CG . LEU L 1 27 ? 75.383 32.462 68.337 1.00 105.36 ? 27 LEU L CG 1 +ATOM 21157 C CD1 . LEU L 1 27 ? 74.046 32.016 67.765 1.00 88.94 ? 27 LEU L CD1 1 +ATOM 21158 C CD2 . LEU L 1 27 ? 75.295 32.590 69.847 1.00 116.35 ? 27 LEU L CD2 1 +ATOM 21159 N N . PRO L 1 28 ? 79.239 30.628 69.681 1.00 85.12 ? 28 PRO L N 1 +ATOM 21160 C CA . PRO L 1 28 ? 80.102 29.504 70.032 1.00 77.04 ? 28 PRO L CA 1 +ATOM 21161 C C . PRO L 1 28 ? 79.525 28.165 69.614 1.00 80.78 ? 28 PRO L C 1 +ATOM 21162 O O . PRO L 1 28 ? 78.377 27.861 69.908 1.00 115.13 ? 28 PRO L O 1 +ATOM 21163 C CB . PRO L 1 28 ? 80.176 29.582 71.546 1.00 80.79 ? 28 PRO L CB 1 +ATOM 21164 C CG . PRO L 1 28 ? 78.933 30.297 71.963 1.00 84.94 ? 28 PRO L CG 1 +ATOM 21165 C CD . PRO L 1 28 ? 78.664 31.280 70.869 1.00 87.88 ? 28 PRO L CD 1 +ATOM 21166 N N . ALA L 1 29 ? 80.320 27.349 68.947 1.00 83.97 ? 29 ALA L N 1 +ATOM 21167 C CA . ALA L 1 29 ? 79.780 26.166 68.270 1.00 90.08 ? 29 ALA L CA 1 +ATOM 21168 C C . ALA L 1 29 ? 79.389 25.059 69.272 1.00 63.21 ? 29 ALA L C 1 +ATOM 21169 O O . ALA L 1 29 ? 80.034 24.890 70.301 1.00 56.56 ? 29 ALA L O 1 +ATOM 21170 C CB . ALA L 1 29 ? 80.783 25.658 67.204 1.00 123.92 ? 29 ALA L CB 1 +ATOM 21171 N N . PRO L 1 30 ? 78.344 24.301 68.959 1.00 54.93 ? 30 PRO L N 1 +ATOM 21172 C CA . PRO L 1 30 ? 78.008 23.097 69.710 1.00 69.09 ? 30 PRO L CA 1 +ATOM 21173 C C . PRO L 1 30 ? 78.985 21.917 69.545 1.00 62.63 ? 30 PRO L C 1 +ATOM 21174 O O . PRO L 1 30 ? 79.817 21.935 68.640 1.00 67.36 ? 30 PRO L O 1 +ATOM 21175 C CB . PRO L 1 30 ? 76.633 22.725 69.128 1.00 83.84 ? 30 PRO L CB 1 +ATOM 21176 C CG . PRO L 1 30 ? 76.691 23.175 67.705 1.00 75.57 ? 30 PRO L CG 1 +ATOM 21177 C CD . PRO L 1 30 ? 77.603 24.379 67.686 1.00 64.97 ? 30 PRO L CD 1 +ATOM 21178 N N . THR L 1 31 ? 78.740 20.829 70.273 1.00 68.63 ? 31 THR L N 1 +ATOM 21179 C CA . THR L 1 31 ? 79.556 19.617 70.144 1.00 86.66 ? 31 THR L CA 1 +ATOM 21180 C C . THR L 1 31 ? 79.412 18.918 68.784 1.00 96.67 ? 31 THR L C 1 +ATOM 21181 O O . THR L 1 31 ? 80.322 18.199 68.339 1.00 114.60 ? 31 THR L O 1 +ATOM 21182 C CB . THR L 1 31 ? 79.291 18.588 71.278 1.00 105.00 ? 31 THR L CB 1 +ATOM 21183 O OG1 . THR L 1 31 ? 77.893 18.261 71.362 1.00 141.62 ? 31 THR L OG1 1 +ATOM 21184 C CG2 . THR L 1 31 ? 79.760 19.135 72.614 1.00 105.15 ? 31 THR L CG2 1 +ATOM 21185 N N . GLY L 1 32 ? 78.253 19.070 68.156 1.00 101.29 ? 32 GLY L N 1 +ATOM 21186 C CA . GLY L 1 32 ? 78.063 18.629 66.771 1.00 115.86 ? 32 GLY L CA 1 +ATOM 21187 C C . GLY L 1 32 ? 76.899 19.392 66.188 1.00 114.56 ? 32 GLY L C 1 +ATOM 21188 O O . GLY L 1 32 ? 76.043 19.866 66.940 1.00 118.23 ? 32 GLY L O 1 +ATOM 21189 N N . LYS L 1 33 ? 76.868 19.557 64.868 1.00 101.67 ? 33 LYS L N 1 +ATOM 21190 C CA . LYS L 1 33 ? 75.741 20.258 64.252 1.00 99.60 ? 33 LYS L CA 1 +ATOM 21191 C C . LYS L 1 33 ? 74.466 19.408 64.348 1.00 102.03 ? 33 LYS L C 1 +ATOM 21192 O O . LYS L 1 33 ? 74.553 18.180 64.410 1.00 97.37 ? 33 LYS L O 1 +ATOM 21193 C CB . LYS L 1 33 ? 76.029 20.624 62.801 1.00 88.62 ? 33 LYS L CB 1 +ATOM 21194 C CG . LYS L 1 33 ? 76.665 21.987 62.622 1.00 88.79 ? 33 LYS L CG 1 +ATOM 21195 C CD . LYS L 1 33 ? 77.083 22.195 61.177 1.00 114.54 ? 33 LYS L CD 1 +ATOM 21196 C CE . LYS L 1 33 ? 78.234 23.187 61.083 1.00 121.01 ? 33 LYS L CE 1 +ATOM 21197 N NZ . LYS L 1 33 ? 78.771 23.281 59.704 1.00 136.68 ? 33 LYS L NZ 1 +ATOM 21198 N N . ILE L 1 34 ? 73.304 20.064 64.412 1.00 88.01 ? 34 ILE L N 1 +ATOM 21199 C CA . ILE L 1 34 ? 72.054 19.362 64.584 1.00 76.68 ? 34 ILE L CA 1 +ATOM 21200 C C . ILE L 1 34 ? 71.320 19.385 63.242 1.00 82.38 ? 34 ILE L C 1 +ATOM 21201 O O . ILE L 1 34 ? 71.418 20.334 62.472 1.00 62.96 ? 34 ILE L O 1 +ATOM 21202 C CB . ILE L 1 34 ? 71.242 19.958 65.765 1.00 99.63 ? 34 ILE L CB 1 +ATOM 21203 C CG1 . ILE L 1 34 ? 71.963 19.712 67.096 1.00 104.04 ? 34 ILE L CG1 1 +ATOM 21204 C CG2 . ILE L 1 34 ? 69.851 19.338 65.888 1.00 124.94 ? 34 ILE L CG2 1 +ATOM 21205 C CD1 . ILE L 1 34 ? 72.371 20.985 67.808 1.00 104.97 ? 34 ILE L CD1 1 +ATOM 21206 N N . PHE L 1 35 ? 70.654 18.271 62.936 1.00 115.97 ? 35 PHE L N 1 +ATOM 21207 C CA . PHE L 1 35 ? 69.869 18.095 61.699 1.00 99.50 ? 35 PHE L CA 1 +ATOM 21208 C C . PHE L 1 35 ? 68.485 18.711 61.848 1.00 59.30 ? 35 PHE L C 1 +ATOM 21209 O O . PHE L 1 35 ? 67.741 18.291 62.733 1.00 72.22 ? 35 PHE L O 1 +ATOM 21210 C CB . PHE L 1 35 ? 69.692 16.586 61.424 1.00 107.21 ? 35 PHE L CB 1 +ATOM 21211 C CG . PHE L 1 35 ? 70.827 15.945 60.662 1.00 98.25 ? 35 PHE L CG 1 +ATOM 21212 C CD1 . PHE L 1 35 ? 71.385 16.559 59.556 1.00 79.51 ? 35 PHE L CD1 1 +ATOM 21213 C CD2 . PHE L 1 35 ? 71.255 14.665 61.003 1.00 99.28 ? 35 PHE L CD2 1 +ATOM 21214 C CE1 . PHE L 1 35 ? 72.421 15.961 58.883 1.00 79.97 ? 35 PHE L CE1 1 +ATOM 21215 C CE2 . PHE L 1 35 ? 72.287 14.053 60.313 1.00 83.30 ? 35 PHE L CE2 1 +ATOM 21216 C CZ . PHE L 1 35 ? 72.860 14.698 59.243 1.00 81.02 ? 35 PHE L CZ 1 +ATOM 21217 N N . VAL L 1 36 ? 68.154 19.651 60.993 1.00 36.64 ? 36 VAL L N 1 +ATOM 21218 C CA . VAL L 1 36 ? 66.885 20.280 61.098 1.00 41.15 ? 36 VAL L CA 1 +ATOM 21219 C C . VAL L 1 36 ? 66.054 20.308 59.790 1.00 55.27 ? 36 VAL L C 1 +ATOM 21220 O O . VAL L 1 36 ? 66.601 20.251 58.691 1.00 91.17 ? 36 VAL L O 1 +ATOM 21221 C CB . VAL L 1 36 ? 67.093 21.685 61.548 1.00 38.40 ? 36 VAL L CB 1 +ATOM 21222 C CG1 . VAL L 1 36 ? 67.601 22.546 60.410 1.00 43.60 ? 36 VAL L CG1 1 +ATOM 21223 C CG2 . VAL L 1 36 ? 65.789 22.256 62.066 1.00 41.56 ? 36 VAL L CG2 1 +ATOM 21224 N N . SER L 1 37 ? 64.719 20.325 59.912 1.00 57.12 ? 37 SER L N 1 +ATOM 21225 C CA . SER L 1 37 ? 63.777 20.313 58.753 1.00 46.87 ? 37 SER L CA 1 +ATOM 21226 C C . SER L 1 37 ? 62.856 21.503 58.795 1.00 45.58 ? 37 SER L C 1 +ATOM 21227 O O . SER L 1 37 ? 62.367 21.839 59.862 1.00 70.08 ? 37 SER L O 1 +ATOM 21228 C CB . SER L 1 37 ? 62.878 19.093 58.793 1.00 29.72 ? 37 SER L CB 1 +ATOM 21229 O OG . SER L 1 37 ? 63.604 17.946 58.424 1.00 29.08 ? 37 SER L OG 1 +ATOM 21230 N N . VAL L 1 38 ? 62.778 22.253 57.714 1.00 40.93 ? 38 VAL L N 1 +ATOM 21231 C CA . VAL L 1 38 ? 61.808 23.323 57.675 1.00 48.23 ? 38 VAL L CA 1 +ATOM 21232 C C . VAL L 1 38 ? 60.913 23.078 56.488 1.00 72.75 ? 38 VAL L C 1 +ATOM 21233 O O . VAL L 1 38 ? 61.399 23.065 55.339 1.00 136.34 ? 38 VAL L O 1 +ATOM 21234 C CB . VAL L 1 38 ? 62.428 24.730 57.500 1.00 56.88 ? 38 VAL L CB 1 +ATOM 21235 C CG1 . VAL L 1 38 ? 61.310 25.762 57.363 1.00 62.56 ? 38 VAL L CG1 1 +ATOM 21236 C CG2 . VAL L 1 38 ? 63.361 25.116 58.648 1.00 51.55 ? 38 VAL L CG2 1 +ATOM 21237 N N . TYR L 1 39 ? 59.619 22.872 56.747 1.00 68.82 ? 39 TYR L N 1 +ATOM 21238 C CA . TYR L 1 39 ? 58.634 22.529 55.694 1.00 45.49 ? 39 TYR L CA 1 +ATOM 21239 C C . TYR L 1 39 ? 58.002 23.824 55.177 1.00 60.13 ? 39 TYR L C 1 +ATOM 21240 O O . TYR L 1 39 ? 58.052 24.115 53.978 1.00 110.86 ? 39 TYR L O 1 +ATOM 21241 C CB . TYR L 1 39 ? 57.594 21.571 56.226 1.00 35.27 ? 39 TYR L CB 1 +ATOM 21242 C CG . TYR L 1 39 ? 58.002 20.158 56.136 1.00 33.56 ? 39 TYR L CG 1 +ATOM 21243 C CD1 . TYR L 1 39 ? 58.856 19.595 57.049 1.00 39.23 ? 39 TYR L CD1 1 +ATOM 21244 C CD2 . TYR L 1 39 ? 57.484 19.339 55.156 1.00 53.53 ? 39 TYR L CD2 1 +ATOM 21245 C CE1 . TYR L 1 39 ? 59.256 18.267 56.938 1.00 57.86 ? 39 TYR L CE1 1 +ATOM 21246 C CE2 . TYR L 1 39 ? 57.856 17.991 55.027 1.00 62.00 ? 39 TYR L CE2 1 +ATOM 21247 C CZ . TYR L 1 39 ? 58.728 17.445 55.917 1.00 56.89 ? 39 TYR L CZ 1 +ATOM 21248 O OH . TYR L 1 39 ? 59.094 16.114 55.800 1.00 31.64 ? 39 TYR L OH 1 +ATOM 21249 N N . ASN L 1 40 ? 57.557 24.693 56.076 1.00 63.76 ? 40 ASN L N 1 +ATOM 21250 C CA . ASN L 1 40 ? 56.935 25.938 55.653 1.00 68.06 ? 40 ASN L CA 1 +ATOM 21251 C C . ASN L 1 40 ? 56.684 26.927 56.790 1.00 66.16 ? 40 ASN L C 1 +ATOM 21252 O O . ASN L 1 40 ? 56.114 26.573 57.823 1.00 62.68 ? 40 ASN L O 1 +ATOM 21253 C CB . ASN L 1 40 ? 55.606 25.640 54.949 1.00 70.42 ? 40 ASN L CB 1 +ATOM 21254 C CG . ASN L 1 40 ? 55.142 26.792 54.082 1.00 93.70 ? 40 ASN L CG 1 +ATOM 21255 O OD1 . ASN L 1 40 ? 55.838 27.246 53.151 1.00 110.83 ? 40 ASN L OD1 1 +ATOM 21256 N ND2 . ASN L 1 40 ? 53.949 27.265 54.371 1.00 105.97 ? 40 ASN L ND2 1 +ATOM 21257 N N . ILE L 1 41 ? 57.054 28.183 56.567 1.00 69.83 ? 41 ILE L N 1 +ATOM 21258 C CA . ILE L 1 41 ? 56.627 29.274 57.432 1.00 81.09 ? 41 ILE L CA 1 +ATOM 21259 C C . ILE L 1 41 ? 55.724 30.236 56.637 1.00 90.63 ? 41 ILE L C 1 +ATOM 21260 O O . ILE L 1 41 ? 56.185 30.890 55.694 1.00 113.59 ? 41 ILE L O 1 +ATOM 21261 C CB . ILE L 1 41 ? 57.838 30.045 58.036 1.00 75.71 ? 41 ILE L CB 1 +ATOM 21262 C CG1 . ILE L 1 41 ? 58.450 29.285 59.220 1.00 62.44 ? 41 ILE L CG1 1 +ATOM 21263 C CG2 . ILE L 1 41 ? 57.402 31.413 58.569 1.00 61.36 ? 41 ILE L CG2 1 +ATOM 21264 C CD1 . ILE L 1 41 ? 59.174 28.015 58.848 1.00 62.88 ? 41 ILE L CD1 1 +ATOM 21265 N N . GLN L 1 42 ? 54.456 30.356 57.043 1.00 79.53 ? 42 GLN L N 1 +ATOM 21266 C CA . GLN L 1 42 ? 53.461 31.092 56.252 1.00 75.37 ? 42 GLN L CA 1 +ATOM 21267 C C . GLN L 1 42 ? 53.442 32.592 56.553 1.00 67.73 ? 42 GLN L C 1 +ATOM 21268 O O . GLN L 1 42 ? 53.766 33.008 57.664 1.00 58.52 ? 42 GLN L O 1 +ATOM 21269 C CB . GLN L 1 42 ? 52.060 30.507 56.459 1.00 81.17 ? 42 GLN L CB 1 +ATOM 21270 C CG . GLN L 1 42 ? 51.893 29.100 55.918 1.00 97.47 ? 42 GLN L CG 1 +ATOM 21271 C CD . GLN L 1 42 ? 51.387 28.050 56.893 1.00 115.83 ? 42 GLN L CD 1 +ATOM 21272 O OE1 . GLN L 1 42 ? 52.107 27.098 57.183 1.00 92.51 ? 42 GLN L OE1 1 +ATOM 21273 N NE2 . GLN L 1 42 ? 50.085 28.095 57.222 1.00 120.41 ? 42 GLN L NE2 1 +ATOM 21274 N N . ASP L 1 43 ? 52.986 33.377 55.570 1.00 63.35 ? 43 ASP L N 1 +ATOM 21275 C CA . ASP L 1 43 ? 52.560 34.746 55.789 1.00 58.30 ? 43 ASP L CA 1 +ATOM 21276 C C . ASP L 1 43 ? 51.159 34.801 56.443 1.00 64.45 ? 43 ASP L C 1 +ATOM 21277 O O . ASP L 1 43 ? 50.224 35.339 55.875 1.00 53.22 ? 43 ASP L O 1 +ATOM 21278 C CB . ASP L 1 43 ? 52.513 35.493 54.477 1.00 59.11 ? 43 ASP L CB 1 +ATOM 21279 C CG . ASP L 1 43 ? 52.354 37.009 54.672 1.00 84.37 ? 43 ASP L CG 1 +ATOM 21280 O OD1 . ASP L 1 43 ? 53.138 37.606 55.446 1.00 106.59 ? 43 ASP L OD1 1 +ATOM 21281 O OD2 . ASP L 1 43 ? 51.513 37.651 53.991 1.00 109.57 ? 43 ASP L OD2 1 +ATOM 21282 N N . GLU L 1 44 ? 51.054 34.331 57.695 1.00 78.87 ? 44 GLU L N 1 +ATOM 21283 C CA . GLU L 1 44 ? 49.770 34.318 58.450 1.00 59.56 ? 44 GLU L CA 1 +ATOM 21284 C C . GLU L 1 44 ? 49.246 35.733 58.786 1.00 55.74 ? 44 GLU L C 1 +ATOM 21285 O O . GLU L 1 44 ? 48.438 35.904 59.691 1.00 68.56 ? 44 GLU L O 1 +ATOM 21286 C CB . GLU L 1 44 ? 49.932 33.433 59.721 1.00 68.82 ? 44 GLU L CB 1 +ATOM 21287 C CG . GLU L 1 44 ? 49.658 31.945 59.515 1.00 65.73 ? 44 GLU L CG 1 +ATOM 21288 C CD . GLU L 1 44 ? 49.858 31.071 60.782 1.00 75.59 ? 44 GLU L CD 1 +ATOM 21289 O OE1 . GLU L 1 44 ? 49.396 31.436 61.905 1.00 80.09 ? 44 GLU L OE1 1 +ATOM 21290 O OE2 . GLU L 1 44 ? 50.427 29.956 60.660 1.00 74.60 ? 44 GLU L OE2 1 +ATOM 21291 N N . THR L 1 45 ? 49.876 36.754 58.199 1.00 56.66 ? 45 THR L N 1 +ATOM 21292 C CA . THR L 1 45 ? 49.731 38.146 58.649 1.00 74.68 ? 45 THR L CA 1 +ATOM 21293 C C . THR L 1 45 ? 48.356 38.682 58.260 1.00 77.05 ? 45 THR L C 1 +ATOM 21294 O O . THR L 1 45 ? 47.766 39.450 59.012 1.00 69.49 ? 45 THR L O 1 +ATOM 21295 C CB . THR L 1 45 ? 50.906 39.092 58.166 1.00 88.49 ? 45 THR L CB 1 +ATOM 21296 O OG1 . THR L 1 45 ? 50.832 40.355 58.831 1.00 90.66 ? 45 THR L OG1 1 +ATOM 21297 C CG2 . THR L 1 45 ? 50.862 39.351 56.670 1.00 104.39 ? 45 THR L CG2 1 +ATOM 21298 N N . GLY L 1 46 ? 47.919 38.391 57.041 1.00 83.55 ? 46 GLY L N 1 +ATOM 21299 C CA . GLY L 1 46 ? 46.574 38.784 56.591 1.00 87.87 ? 46 GLY L CA 1 +ATOM 21300 C C . GLY L 1 46 ? 46.513 40.155 55.935 1.00 80.96 ? 46 GLY L C 1 +ATOM 21301 O O . GLY L 1 46 ? 45.467 40.811 55.819 1.00 49.41 ? 46 GLY L O 1 +ATOM 21302 N N . GLN L 1 47 ? 47.659 40.619 55.489 1.00 88.92 ? 47 GLN L N 1 +ATOM 21303 C CA . GLN L 1 47 ? 47.765 42.007 55.237 1.00 80.72 ? 47 GLN L CA 1 +ATOM 21304 C C . GLN L 1 47 ? 48.360 42.302 53.874 1.00 72.91 ? 47 GLN L C 1 +ATOM 21305 O O . GLN L 1 47 ? 49.304 41.648 53.413 1.00 55.01 ? 47 GLN L O 1 +ATOM 21306 C CB . GLN L 1 47 ? 48.575 42.634 56.330 1.00 69.25 ? 47 GLN L CB 1 +ATOM 21307 C CG . GLN L 1 47 ? 47.844 42.633 57.637 1.00 76.21 ? 47 GLN L CG 1 +ATOM 21308 C CD . GLN L 1 47 ? 46.422 43.166 57.500 1.00 87.41 ? 47 GLN L CD 1 +ATOM 21309 O OE1 . GLN L 1 47 ? 46.217 44.371 57.399 1.00 83.04 ? 47 GLN L OE1 1 +ATOM 21310 N NE2 . GLN L 1 47 ? 45.441 42.287 57.650 1.00 78.20 ? 47 GLN L NE2 1 +ATOM 21311 N N . PHE L 1 48 ? 47.760 43.301 53.236 1.00 58.92 ? 48 PHE L N 1 +ATOM 21312 C CA . PHE L 1 48 ? 48.196 43.770 51.946 1.00 53.26 ? 48 PHE L CA 1 +ATOM 21313 C C . PHE L 1 48 ? 48.487 45.261 52.005 1.00 65.97 ? 48 PHE L C 1 +ATOM 21314 O O . PHE L 1 48 ? 48.076 45.976 52.939 1.00 62.84 ? 48 PHE L O 1 +ATOM 21315 C CB . PHE L 1 48 ? 47.113 43.500 50.909 1.00 53.24 ? 48 PHE L CB 1 +ATOM 21316 C CG . PHE L 1 48 ? 46.884 42.062 50.686 1.00 43.58 ? 48 PHE L CG 1 +ATOM 21317 C CD1 . PHE L 1 48 ? 46.178 41.307 51.617 1.00 34.54 ? 48 PHE L CD1 1 +ATOM 21318 C CD2 . PHE L 1 48 ? 47.427 41.465 49.597 1.00 46.76 ? 48 PHE L CD2 1 +ATOM 21319 C CE1 . PHE L 1 48 ? 46.004 39.973 51.470 1.00 34.38 ? 48 PHE L CE1 1 +ATOM 21320 C CE2 . PHE L 1 48 ? 47.288 40.121 49.448 1.00 55.95 ? 48 PHE L CE2 1 +ATOM 21321 C CZ . PHE L 1 48 ? 46.581 39.371 50.388 1.00 47.51 ? 48 PHE L CZ 1 +ATOM 21322 N N . LYS L 1 49 ? 49.135 45.741 50.948 1.00 78.42 ? 49 LYS L N 1 +ATOM 21323 C CA . LYS L 1 49 ? 49.529 47.141 50.853 1.00 80.78 ? 49 LYS L CA 1 +ATOM 21324 C C . LYS L 1 49 ? 48.330 48.000 50.481 1.00 79.47 ? 49 LYS L C 1 +ATOM 21325 O O . LYS L 1 49 ? 47.436 47.540 49.760 1.00 96.22 ? 49 LYS L O 1 +ATOM 21326 C CB . LYS L 1 49 ? 50.674 47.322 49.856 1.00 75.67 ? 49 LYS L CB 1 +ATOM 21327 C CG . LYS L 1 49 ? 51.954 46.626 50.303 1.00 86.66 ? 49 LYS L CG 1 +ATOM 21328 C CD . LYS L 1 49 ? 53.211 46.913 49.495 1.00 93.51 ? 49 LYS L CD 1 +ATOM 21329 C CE . LYS L 1 49 ? 54.391 46.269 50.235 1.00 102.94 ? 49 LYS L CE 1 +ATOM 21330 N NZ . LYS L 1 49 ? 55.736 46.479 49.635 1.00 96.08 ? 49 LYS L NZ 1 +ATOM 21331 N N . PRO L 1 50 ? 48.271 49.211 51.049 1.00 78.93 ? 50 PRO L N 1 +ATOM 21332 C CA . PRO L 1 50 ? 47.188 50.133 50.808 1.00 85.84 ? 50 PRO L CA 1 +ATOM 21333 C C . PRO L 1 50 ? 47.389 50.871 49.501 1.00 85.64 ? 50 PRO L C 1 +ATOM 21334 O O . PRO L 1 50 ? 48.461 50.756 48.849 1.00 74.58 ? 50 PRO L O 1 +ATOM 21335 C CB . PRO L 1 50 ? 47.286 51.114 51.969 1.00 99.45 ? 50 PRO L CB 1 +ATOM 21336 C CG . PRO L 1 50 ? 48.723 51.100 52.352 1.00 110.94 ? 50 PRO L CG 1 +ATOM 21337 C CD . PRO L 1 50 ? 49.211 49.713 52.070 1.00 104.77 ? 50 PRO L CD 1 +ATOM 21338 N N . TYR L 1 51 ? 46.341 51.569 49.074 1.00 80.40 ? 51 TYR L N 1 +ATOM 21339 C CA . TYR L 1 51 ? 46.446 52.383 47.880 1.00 83.29 ? 51 TYR L CA 1 +ATOM 21340 C C . TYR L 1 51 ? 47.678 53.275 48.033 1.00 91.59 ? 51 TYR L C 1 +ATOM 21341 O O . TYR L 1 51 ? 47.897 53.826 49.108 1.00 66.10 ? 51 TYR L O 1 +ATOM 21342 C CB . TYR L 1 51 ? 45.193 53.230 47.702 1.00 73.15 ? 51 TYR L CB 1 +ATOM 21343 C CG . TYR L 1 51 ? 45.137 53.852 46.337 1.00 90.11 ? 51 TYR L CG 1 +ATOM 21344 C CD1 . TYR L 1 51 ? 44.603 53.150 45.263 1.00 93.79 ? 51 TYR L CD1 1 +ATOM 21345 C CD2 . TYR L 1 51 ? 45.644 55.127 46.098 1.00 115.96 ? 51 TYR L CD2 1 +ATOM 21346 C CE1 . TYR L 1 51 ? 44.576 53.677 43.987 1.00 94.85 ? 51 TYR L CE1 1 +ATOM 21347 C CE2 . TYR L 1 51 ? 45.593 55.683 44.815 1.00 132.74 ? 51 TYR L CE2 1 +ATOM 21348 C CZ . TYR L 1 51 ? 45.085 54.926 43.761 1.00 119.83 ? 51 TYR L CZ 1 +ATOM 21349 O OH . TYR L 1 51 ? 45.005 55.419 42.475 1.00 149.99 ? 51 TYR L OH 1 +ATOM 21350 N N . PRO L 1 52 ? 48.484 53.434 46.954 1.00 102.08 ? 52 PRO L N 1 +ATOM 21351 C CA . PRO L 1 52 ? 48.284 53.002 45.558 1.00 104.29 ? 52 PRO L CA 1 +ATOM 21352 C C . PRO L 1 52 ? 48.905 51.679 45.134 1.00 104.23 ? 52 PRO L C 1 +ATOM 21353 O O . PRO L 1 52 ? 49.019 51.428 43.938 1.00 126.19 ? 52 PRO L O 1 +ATOM 21354 C CB . PRO L 1 52 ? 48.970 54.109 44.772 1.00 120.95 ? 52 PRO L CB 1 +ATOM 21355 C CG . PRO L 1 52 ? 50.118 54.499 45.648 1.00 128.44 ? 52 PRO L CG 1 +ATOM 21356 C CD . PRO L 1 52 ? 49.633 54.353 47.069 1.00 111.21 ? 52 PRO L CD 1 +ATOM 21357 N N . ALA L 1 53 ? 49.220 50.808 46.082 1.00 112.03 ? 53 ALA L N 1 +ATOM 21358 C CA . ALA L 1 53 ? 49.707 49.476 45.725 1.00 94.11 ? 53 ALA L CA 1 +ATOM 21359 C C . ALA L 1 53 ? 48.642 48.662 45.006 1.00 77.02 ? 53 ALA L C 1 +ATOM 21360 O O . ALA L 1 53 ? 47.428 48.960 45.076 1.00 55.25 ? 53 ALA L O 1 +ATOM 21361 C CB . ALA L 1 53 ? 50.169 48.731 46.955 1.00 90.97 ? 53 ALA L CB 1 +ATOM 21362 N N . SER L 1 54 ? 49.097 47.632 44.302 1.00 74.89 ? 54 SER L N 1 +ATOM 21363 C CA . SER L 1 54 ? 48.157 46.654 43.783 1.00 83.04 ? 54 SER L CA 1 +ATOM 21364 C C . SER L 1 54 ? 47.389 46.065 44.981 1.00 75.45 ? 54 SER L C 1 +ATOM 21365 O O . SER L 1 54 ? 47.934 45.818 46.040 1.00 46.90 ? 54 SER L O 1 +ATOM 21366 C CB . SER L 1 54 ? 48.843 45.543 42.947 1.00 66.60 ? 54 SER L CB 1 +ATOM 21367 O OG . SER L 1 54 ? 48.049 44.363 42.875 1.00 44.15 ? 54 SER L OG 1 +ATOM 21368 N N . ASN L 1 55 ? 46.113 45.810 44.752 1.00 66.15 ? 55 ASN L N 1 +ATOM 21369 C CA . ASN L 1 55 ? 45.273 45.148 45.709 1.00 54.69 ? 55 ASN L CA 1 +ATOM 21370 C C . ASN L 1 55 ? 45.915 43.893 46.257 1.00 55.27 ? 55 ASN L C 1 +ATOM 21371 O O . ASN L 1 55 ? 45.672 43.469 47.384 1.00 45.22 ? 55 ASN L O 1 +ATOM 21372 C CB . ASN L 1 55 ? 43.959 44.793 45.021 1.00 55.81 ? 55 ASN L CB 1 +ATOM 21373 C CG . ASN L 1 55 ? 42.885 44.452 46.002 1.00 78.49 ? 55 ASN L CG 1 +ATOM 21374 O OD1 . ASN L 1 55 ? 42.936 44.805 47.183 1.00 109.29 ? 55 ASN L OD1 1 +ATOM 21375 N ND2 . ASN L 1 55 ? 41.858 43.838 45.501 1.00 102.80 ? 55 ASN L ND2 1 +ATOM 21376 N N . PHE L 1 56 ? 46.716 43.254 45.406 1.00 68.78 ? 56 PHE L N 1 +ATOM 21377 C CA . PHE L 1 56 ? 47.251 41.907 45.676 1.00 64.59 ? 56 PHE L CA 1 +ATOM 21378 C C . PHE L 1 56 ? 48.647 41.942 46.265 1.00 77.38 ? 56 PHE L C 1 +ATOM 21379 O O . PHE L 1 56 ? 49.270 40.899 46.439 1.00 73.40 ? 56 PHE L O 1 +ATOM 21380 C CB . PHE L 1 56 ? 47.331 41.080 44.399 1.00 56.16 ? 56 PHE L CB 1 +ATOM 21381 C CG . PHE L 1 56 ? 46.030 40.873 43.759 1.00 56.35 ? 56 PHE L CG 1 +ATOM 21382 C CD1 . PHE L 1 56 ? 44.990 40.272 44.415 1.00 55.66 ? 56 PHE L CD1 1 +ATOM 21383 C CD2 . PHE L 1 56 ? 45.816 41.401 42.522 1.00 91.96 ? 56 PHE L CD2 1 +ATOM 21384 C CE1 . PHE L 1 56 ? 43.754 40.161 43.827 1.00 75.81 ? 56 PHE L CE1 1 +ATOM 21385 C CE2 . PHE L 1 56 ? 44.590 41.255 41.897 1.00 116.21 ? 56 PHE L CE2 1 +ATOM 21386 C CZ . PHE L 1 56 ? 43.553 40.638 42.557 1.00 103.07 ? 56 PHE L CZ 1 +ATOM 21387 N N . SER L 1 57 ? 49.216 43.130 46.418 1.00 93.23 ? 57 SER L N 1 +ATOM 21388 C CA . SER L 1 57 ? 50.573 43.217 46.941 1.00 92.97 ? 57 SER L CA 1 +ATOM 21389 C C . SER L 1 57 ? 50.523 42.945 48.444 1.00 84.87 ? 57 SER L C 1 +ATOM 21390 O O . SER L 1 57 ? 49.926 43.699 49.208 1.00 64.90 ? 57 SER L O 1 +ATOM 21391 C CB . SER L 1 57 ? 51.199 44.591 46.630 1.00 108.58 ? 57 SER L CB 1 +ATOM 21392 O OG . SER L 1 57 ? 51.568 44.670 45.262 1.00 108.85 ? 57 SER L OG 1 +ATOM 21393 N N . THR L 1 58 ? 51.135 41.848 48.849 1.00 83.20 ? 58 THR L N 1 +ATOM 21394 C CA . THR L 1 58 ? 51.179 41.502 50.243 1.00 79.58 ? 58 THR L CA 1 +ATOM 21395 C C . THR L 1 58 ? 52.067 42.417 51.002 1.00 80.32 ? 58 THR L C 1 +ATOM 21396 O O . THR L 1 58 ? 53.032 42.996 50.499 1.00 106.76 ? 58 THR L O 1 +ATOM 21397 C CB . THR L 1 58 ? 51.759 40.118 50.434 1.00 91.60 ? 58 THR L CB 1 +ATOM 21398 O OG1 . THR L 1 58 ? 53.096 40.067 49.927 1.00 68.89 ? 58 THR L OG1 1 +ATOM 21399 C CG2 . THR L 1 58 ? 50.928 39.128 49.669 1.00 117.45 ? 58 THR L CG2 1 +ATOM 21400 N N . ALA L 1 59 ? 51.769 42.567 52.257 1.00 92.27 ? 59 ALA L N 1 +ATOM 21401 C CA . ALA L 1 59 ? 52.545 43.540 52.984 1.00 99.39 ? 59 ALA L CA 1 +ATOM 21402 C C . ALA L 1 59 ? 53.923 42.981 53.272 1.00 64.25 ? 59 ALA L C 1 +ATOM 21403 O O . ALA L 1 59 ? 54.818 43.711 53.675 1.00 54.92 ? 59 ALA L O 1 +ATOM 21404 C CB . ALA L 1 59 ? 51.805 43.972 54.239 1.00 117.59 ? 59 ALA L CB 1 +ATOM 21405 N N . VAL L 1 60 ? 54.039 41.663 53.191 1.00 57.60 ? 60 VAL L N 1 +ATOM 21406 C CA . VAL L 1 60 ? 55.192 40.950 53.739 1.00 61.15 ? 60 VAL L CA 1 +ATOM 21407 C C . VAL L 1 60 ? 55.590 39.879 52.744 1.00 41.91 ? 60 VAL L C 1 +ATOM 21408 O O . VAL L 1 60 ? 54.735 39.272 52.131 1.00 35.01 ? 60 VAL L O 1 +ATOM 21409 C CB . VAL L 1 60 ? 54.856 40.233 55.088 1.00 81.38 ? 60 VAL L CB 1 +ATOM 21410 C CG1 . VAL L 1 60 ? 56.058 39.463 55.617 1.00 76.96 ? 60 VAL L CG1 1 +ATOM 21411 C CG2 . VAL L 1 60 ? 54.368 41.224 56.146 1.00 96.71 ? 60 VAL L CG2 1 +ATOM 21412 N N . PRO L 1 61 ? 56.888 39.672 52.570 1.00 31.52 ? 61 PRO L N 1 +ATOM 21413 C CA . PRO L 1 61 ? 57.296 38.776 51.507 1.00 28.15 ? 61 PRO L CA 1 +ATOM 21414 C C . PRO L 1 61 ? 56.987 37.393 51.901 1.00 26.82 ? 61 PRO L C 1 +ATOM 21415 O O . PRO L 1 61 ? 57.042 37.052 53.090 1.00 19.07 ? 61 PRO L O 1 +ATOM 21416 C CB . PRO L 1 61 ? 58.811 38.989 51.414 1.00 29.78 ? 61 PRO L CB 1 +ATOM 21417 C CG . PRO L 1 61 ? 59.191 39.681 52.705 1.00 35.06 ? 61 PRO L CG 1 +ATOM 21418 C CD . PRO L 1 61 ? 58.004 40.533 53.031 1.00 35.09 ? 61 PRO L CD 1 +ATOM 21419 N N . GLN L 1 62 ? 56.722 36.574 50.893 1.00 40.19 ? 62 GLN L N 1 +ATOM 21420 C CA . GLN L 1 62 ? 56.269 35.211 51.118 1.00 52.85 ? 62 GLN L CA 1 +ATOM 21421 C C . GLN L 1 62 ? 57.444 34.295 51.137 1.00 41.61 ? 62 GLN L C 1 +ATOM 21422 O O . GLN L 1 62 ? 57.337 33.165 50.736 1.00 48.84 ? 62 GLN L O 1 +ATOM 21423 C CB . GLN L 1 62 ? 55.301 34.755 49.997 1.00 67.36 ? 62 GLN L CB 1 +ATOM 21424 C CG . GLN L 1 62 ? 54.141 35.712 49.697 1.00 70.73 ? 62 GLN L CG 1 +ATOM 21425 C CD . GLN L 1 62 ? 53.259 35.975 50.889 1.00 67.88 ? 62 GLN L CD 1 +ATOM 21426 O OE1 . GLN L 1 62 ? 52.451 35.127 51.290 1.00 87.23 ? 62 GLN L OE1 1 +ATOM 21427 N NE2 . GLN L 1 62 ? 53.477 37.114 51.535 1.00 60.18 ? 62 GLN L NE2 1 +ATOM 21428 N N . SER L 1 63 ? 58.516 34.739 51.735 1.00 54.82 ? 63 SER L N 1 +ATOM 21429 C CA . SER L 1 63 ? 59.808 34.091 51.559 1.00 81.35 ? 63 SER L CA 1 +ATOM 21430 C C . SER L 1 63 ? 60.453 33.691 52.894 1.00 113.25 ? 63 SER L C 1 +ATOM 21431 O O . SER L 1 63 ? 61.593 33.235 52.938 1.00 68.71 ? 63 SER L O 1 +ATOM 21432 C CB . SER L 1 63 ? 60.749 35.027 50.790 1.00 85.05 ? 63 SER L CB 1 +ATOM 21433 O OG . SER L 1 63 ? 61.004 36.236 51.472 1.00 47.40 ? 63 SER L OG 1 +ATOM 21434 N N . ALA L 1 64 ? 59.664 33.762 53.963 1.00 153.29 ? 64 ALA L N 1 +ATOM 21435 C CA . ALA L 1 64 ? 60.167 33.526 55.310 1.00 144.02 ? 64 ALA L CA 1 +ATOM 21436 C C . ALA L 1 64 ? 60.874 32.156 55.449 1.00 109.28 ? 64 ALA L C 1 +ATOM 21437 O O . ALA L 1 64 ? 61.864 32.019 56.173 1.00 85.74 ? 64 ALA L O 1 +ATOM 21438 C CB . ALA L 1 64 ? 59.017 33.671 56.310 1.00 147.18 ? 64 ALA L CB 1 +ATOM 21439 N N . THR L 1 65 ? 60.290 31.132 54.832 1.00 80.54 ? 65 THR L N 1 +ATOM 21440 C CA . THR L 1 65 ? 60.769 29.764 54.959 1.00 64.27 ? 65 THR L CA 1 +ATOM 21441 C C . THR L 1 65 ? 62.228 29.674 54.581 1.00 55.48 ? 65 THR L C 1 +ATOM 21442 O O . THR L 1 65 ? 63.028 29.085 55.307 1.00 82.29 ? 65 THR L O 1 +ATOM 21443 C CB . THR L 1 65 ? 59.994 28.870 54.003 1.00 82.86 ? 65 THR L CB 1 +ATOM 21444 O OG1 . THR L 1 65 ? 58.613 29.261 53.995 1.00 83.49 ? 65 THR L OG1 1 +ATOM 21445 C CG2 . THR L 1 65 ? 60.142 27.389 54.370 1.00 67.27 ? 65 THR L CG2 1 +ATOM 21446 N N . ALA L 1 66 ? 62.575 30.265 53.453 1.00 52.70 ? 66 ALA L N 1 +ATOM 21447 C CA . ALA L 1 66 ? 63.917 30.169 52.963 1.00 71.38 ? 66 ALA L CA 1 +ATOM 21448 C C . ALA L 1 66 ? 64.875 30.996 53.851 1.00 87.96 ? 66 ALA L C 1 +ATOM 21449 O O . ALA L 1 66 ? 66.044 30.613 54.053 1.00 89.79 ? 66 ALA L O 1 +ATOM 21450 C CB . ALA L 1 66 ? 63.972 30.630 51.520 1.00 84.64 ? 66 ALA L CB 1 +ATOM 21451 N N . MET L 1 67 ? 64.384 32.120 54.373 1.00 85.33 ? 67 MET L N 1 +ATOM 21452 C CA . MET L 1 67 ? 65.191 32.960 55.272 1.00 87.25 ? 67 MET L CA 1 +ATOM 21453 C C . MET L 1 67 ? 65.546 32.182 56.545 1.00 68.75 ? 67 MET L C 1 +ATOM 21454 O O . MET L 1 67 ? 66.643 32.247 57.051 1.00 61.63 ? 67 MET L O 1 +ATOM 21455 C CB . MET L 1 67 ? 64.418 34.238 55.645 1.00 107.46 ? 67 MET L CB 1 +ATOM 21456 C CG . MET L 1 67 ? 64.246 35.268 54.536 1.00 110.45 ? 67 MET L CG 1 +ATOM 21457 S SD . MET L 1 67 ? 63.059 36.560 54.986 1.00 89.60 ? 67 MET L SD 1 +ATOM 21458 C CE . MET L 1 67 ? 63.221 37.692 53.616 1.00 126.37 ? 67 MET L CE 1 +ATOM 21459 N N . LEU L 1 68 ? 64.569 31.463 57.075 1.00 58.37 ? 68 LEU L N 1 +ATOM 21460 C CA . LEU L 1 68 ? 64.785 30.696 58.269 1.00 49.59 ? 68 LEU L CA 1 +ATOM 21461 C C . LEU L 1 68 ? 65.828 29.649 57.986 1.00 59.32 ? 68 LEU L C 1 +ATOM 21462 O O . LEU L 1 68 ? 66.649 29.368 58.844 1.00 73.55 ? 68 LEU L O 1 +ATOM 21463 C CB . LEU L 1 68 ? 63.472 30.036 58.760 1.00 60.30 ? 68 LEU L CB 1 +ATOM 21464 C CG . LEU L 1 68 ? 63.680 29.013 59.884 1.00 73.62 ? 68 LEU L CG 1 +ATOM 21465 C CD1 . LEU L 1 68 ? 64.199 29.688 61.145 1.00 85.30 ? 68 LEU L CD1 1 +ATOM 21466 C CD2 . LEU L 1 68 ? 62.421 28.220 60.206 1.00 75.61 ? 68 LEU L CD2 1 +ATOM 21467 N N . VAL L 1 69 ? 65.695 28.931 56.862 1.00 79.37 ? 69 VAL L N 1 +ATOM 21468 C CA . VAL L 1 69 ? 66.606 27.804 56.553 1.00 76.23 ? 69 VAL L CA 1 +ATOM 21469 C C . VAL L 1 69 ? 68.012 28.358 56.428 1.00 56.45 ? 69 VAL L C 1 +ATOM 21470 O O . VAL L 1 69 ? 68.960 27.802 56.995 1.00 44.16 ? 69 VAL L O 1 +ATOM 21471 C CB . VAL L 1 69 ? 66.256 27.083 55.233 1.00 83.21 ? 69 VAL L CB 1 +ATOM 21472 C CG1 . VAL L 1 69 ? 67.365 26.111 54.870 1.00 87.64 ? 69 VAL L CG1 1 +ATOM 21473 C CG2 . VAL L 1 69 ? 64.936 26.332 55.325 1.00 87.43 ? 69 VAL L CG2 1 +ATOM 21474 N N . THR L 1 70 ? 68.108 29.513 55.787 1.00 45.62 ? 70 THR L N 1 +ATOM 21475 C CA . THR L 1 70 ? 69.377 30.180 55.657 1.00 67.81 ? 70 THR L CA 1 +ATOM 21476 C C . THR L 1 70 ? 69.974 30.620 57.016 1.00 72.99 ? 70 THR L C 1 +ATOM 21477 O O . THR L 1 70 ? 71.164 30.404 57.295 1.00 86.33 ? 70 THR L O 1 +ATOM 21478 C CB . THR L 1 70 ? 69.235 31.397 54.751 1.00 87.88 ? 70 THR L CB 1 +ATOM 21479 O OG1 . THR L 1 70 ? 68.687 30.970 53.505 1.00 98.18 ? 70 THR L OG1 1 +ATOM 21480 C CG2 . THR L 1 70 ? 70.611 32.054 54.505 1.00 125.35 ? 70 THR L CG2 1 +ATOM 21481 N N . ALA L 1 71 ? 69.153 31.220 57.865 1.00 59.39 ? 71 ALA L N 1 +ATOM 21482 C CA . ALA L 1 71 ? 69.611 31.596 59.203 1.00 48.65 ? 71 ALA L CA 1 +ATOM 21483 C C . ALA L 1 71 ? 70.070 30.359 60.015 1.00 44.05 ? 71 ALA L C 1 +ATOM 21484 O O . ALA L 1 71 ? 71.047 30.400 60.726 1.00 39.34 ? 71 ALA L O 1 +ATOM 21485 C CB . ALA L 1 71 ? 68.491 32.339 59.932 1.00 60.45 ? 71 ALA L CB 1 +ATOM 21486 N N . LEU L 1 72 ? 69.300 29.278 59.947 1.00 48.25 ? 72 LEU L N 1 +ATOM 21487 C CA . LEU L 1 72 ? 69.652 28.041 60.627 1.00 51.24 ? 72 LEU L CA 1 +ATOM 21488 C C . LEU L 1 72 ? 70.993 27.515 60.143 1.00 64.65 ? 72 LEU L C 1 +ATOM 21489 O O . LEU L 1 72 ? 71.671 26.801 60.863 1.00 58.84 ? 72 LEU L O 1 +ATOM 21490 C CB . LEU L 1 72 ? 68.585 26.968 60.385 1.00 53.40 ? 72 LEU L CB 1 +ATOM 21491 C CG . LEU L 1 72 ? 67.242 27.258 61.041 1.00 50.14 ? 72 LEU L CG 1 +ATOM 21492 C CD1 . LEU L 1 72 ? 66.186 26.358 60.403 1.00 66.68 ? 72 LEU L CD1 1 +ATOM 21493 C CD2 . LEU L 1 72 ? 67.288 27.015 62.526 1.00 57.11 ? 72 LEU L CD2 1 +ATOM 21494 N N . LYS L 1 73 ? 71.355 27.826 58.894 1.00 80.71 ? 73 LYS L N 1 +ATOM 21495 C CA . LYS L 1 73 ? 72.641 27.375 58.341 1.00 75.96 ? 73 LYS L CA 1 +ATOM 21496 C C . LYS L 1 73 ? 73.772 28.297 58.743 1.00 86.83 ? 73 LYS L C 1 +ATOM 21497 O O . LYS L 1 73 ? 74.826 27.823 59.181 1.00 117.93 ? 73 LYS L O 1 +ATOM 21498 C CB . LYS L 1 73 ? 72.615 27.286 56.824 1.00 62.42 ? 73 LYS L CB 1 +ATOM 21499 C CG . LYS L 1 73 ? 73.818 26.552 56.250 1.00 67.15 ? 73 LYS L CG 1 +ATOM 21500 C CD . LYS L 1 73 ? 73.758 26.482 54.724 1.00 90.74 ? 73 LYS L CD 1 +ATOM 21501 C CE . LYS L 1 73 ? 75.143 26.392 54.094 1.00 114.79 ? 73 LYS L CE 1 +ATOM 21502 N NZ . LYS L 1 73 ? 75.397 25.091 53.407 1.00 126.93 ? 73 LYS L NZ 1 +ATOM 21503 N N . ASP L 1 74 ? 73.541 29.609 58.647 1.00 80.88 ? 74 ASP L N 1 +ATOM 21504 C CA . ASP L 1 74 ? 74.577 30.598 58.979 1.00 102.61 ? 74 ASP L CA 1 +ATOM 21505 C C . ASP L 1 74 ? 75.029 30.538 60.443 1.00 121.82 ? 74 ASP L C 1 +ATOM 21506 O O . ASP L 1 74 ? 76.197 30.805 60.745 1.00 118.75 ? 74 ASP L O 1 +ATOM 21507 C CB . ASP L 1 74 ? 74.081 32.001 58.686 1.00 107.98 ? 74 ASP L CB 1 +ATOM 21508 C CG . ASP L 1 74 ? 73.875 32.257 57.195 1.00 122.34 ? 74 ASP L CG 1 +ATOM 21509 O OD1 . ASP L 1 74 ? 74.599 31.671 56.344 1.00 174.26 ? 74 ASP L OD1 1 +ATOM 21510 O OD2 . ASP L 1 74 ? 73.044 33.135 56.883 1.00 111.44 ? 74 ASP L OD2 1 +ATOM 21511 N N . SER L 1 75 ? 74.133 30.075 61.322 1.00 123.09 ? 75 SER L N 1 +ATOM 21512 C CA . SER L 1 75 ? 74.429 29.940 62.752 1.00 95.13 ? 75 SER L CA 1 +ATOM 21513 C C . SER L 1 75 ? 75.544 28.919 63.063 1.00 102.73 ? 75 SER L C 1 +ATOM 21514 O O . SER L 1 75 ? 76.208 29.013 64.093 1.00 81.87 ? 75 SER L O 1 +ATOM 21515 C CB . SER L 1 75 ? 73.172 29.530 63.510 1.00 84.33 ? 75 SER L CB 1 +ATOM 21516 O OG . SER L 1 75 ? 73.007 28.113 63.536 1.00 73.60 ? 75 SER L OG 1 +ATOM 21517 N N . ARG L 1 76 ? 75.705 27.930 62.178 1.00 91.26 ? 76 ARG L N 1 +ATOM 21518 C CA . ARG L 1 76 ? 76.688 26.856 62.319 1.00 73.18 ? 76 ARG L CA 1 +ATOM 21519 C C . ARG L 1 76 ? 76.359 26.016 63.516 1.00 61.75 ? 76 ARG L C 1 +ATOM 21520 O O . ARG L 1 76 ? 77.244 25.523 64.206 1.00 49.05 ? 76 ARG L O 1 +ATOM 21521 C CB . ARG L 1 76 ? 78.112 27.397 62.401 1.00 79.83 ? 76 ARG L CB 1 +ATOM 21522 C CG . ARG L 1 76 ? 78.587 28.164 61.168 1.00 96.35 ? 76 ARG L CG 1 +ATOM 21523 C CD . ARG L 1 76 ? 80.027 28.631 61.343 1.00 116.67 ? 76 ARG L CD 1 +ATOM 21524 N NE . ARG L 1 76 ? 80.135 29.679 62.372 1.00 141.70 ? 76 ARG L NE 1 +ATOM 21525 C CZ . ARG L 1 76 ? 80.427 29.473 63.660 1.00 151.64 ? 76 ARG L CZ 1 +ATOM 21526 N NH1 . ARG L 1 76 ? 80.671 28.250 64.131 1.00 155.29 ? 76 ARG L NH1 1 +ATOM 21527 N NH2 . ARG L 1 76 ? 80.485 30.506 64.486 1.00 124.55 ? 76 ARG L NH2 1 +ATOM 21528 N N . TRP L 1 77 ? 75.063 25.845 63.734 1.00 67.59 ? 77 TRP L N 1 +ATOM 21529 C CA . TRP L 1 77 ? 74.545 24.910 64.730 1.00 85.72 ? 77 TRP L CA 1 +ATOM 21530 C C . TRP L 1 77 ? 73.747 23.778 64.063 1.00 74.30 ? 77 TRP L C 1 +ATOM 21531 O O . TRP L 1 77 ? 73.760 22.636 64.530 1.00 57.88 ? 77 TRP L O 1 +ATOM 21532 C CB . TRP L 1 77 ? 73.641 25.659 65.725 1.00 82.21 ? 77 TRP L CB 1 +ATOM 21533 C CG . TRP L 1 77 ? 74.347 26.181 66.952 1.00 75.51 ? 77 TRP L CG 1 +ATOM 21534 C CD1 . TRP L 1 77 ? 75.157 27.260 67.025 1.00 83.01 ? 77 TRP L CD1 1 +ATOM 21535 C CD2 . TRP L 1 77 ? 74.303 25.626 68.259 1.00 73.56 ? 77 TRP L CD2 1 +ATOM 21536 N NE1 . TRP L 1 77 ? 75.632 27.410 68.297 1.00 76.16 ? 77 TRP L NE1 1 +ATOM 21537 C CE2 . TRP L 1 77 ? 75.125 26.413 69.076 1.00 67.63 ? 77 TRP L CE2 1 +ATOM 21538 C CE3 . TRP L 1 77 ? 73.646 24.531 68.817 1.00 100.74 ? 77 TRP L CE3 1 +ATOM 21539 C CZ2 . TRP L 1 77 ? 75.293 26.163 70.425 1.00 80.23 ? 77 TRP L CZ2 1 +ATOM 21540 C CZ3 . TRP L 1 77 ? 73.818 24.274 70.167 1.00 109.51 ? 77 TRP L CZ3 1 +ATOM 21541 C CH2 . TRP L 1 77 ? 74.646 25.081 70.955 1.00 98.61 ? 77 TRP L CH2 1 +ATOM 21542 N N . PHE L 1 78 ? 73.089 24.116 62.958 1.00 67.38 ? 78 PHE L N 1 +ATOM 21543 C CA . PHE L 1 78 ? 72.186 23.213 62.278 1.00 75.78 ? 78 PHE L CA 1 +ATOM 21544 C C . PHE L 1 78 ? 72.607 22.933 60.825 1.00 77.05 ? 78 PHE L C 1 +ATOM 21545 O O . PHE L 1 78 ? 73.055 23.830 60.110 1.00 58.59 ? 78 PHE L O 1 +ATOM 21546 C CB . PHE L 1 78 ? 70.789 23.824 62.239 1.00 82.89 ? 78 PHE L CB 1 +ATOM 21547 C CG . PHE L 1 78 ? 70.257 24.207 63.580 1.00 71.48 ? 78 PHE L CG 1 +ATOM 21548 C CD1 . PHE L 1 78 ? 69.781 23.245 64.445 1.00 82.34 ? 78 PHE L CD1 1 +ATOM 21549 C CD2 . PHE L 1 78 ? 70.184 25.517 63.948 1.00 60.17 ? 78 PHE L CD2 1 +ATOM 21550 C CE1 . PHE L 1 78 ? 69.271 23.601 65.674 1.00 75.61 ? 78 PHE L CE1 1 +ATOM 21551 C CE2 . PHE L 1 78 ? 69.677 25.876 65.176 1.00 54.10 ? 78 PHE L CE2 1 +ATOM 21552 C CZ . PHE L 1 78 ? 69.187 24.927 66.022 1.00 57.20 ? 78 PHE L CZ 1 +ATOM 21553 N N . ILE L 1 79 ? 72.381 21.691 60.387 1.00 67.87 ? 79 ILE L N 1 +ATOM 21554 C CA . ILE L 1 79 ? 72.365 21.333 58.980 1.00 56.26 ? 79 ILE L CA 1 +ATOM 21555 C C . ILE L 1 79 ? 70.922 21.293 58.546 1.00 52.73 ? 79 ILE L C 1 +ATOM 21556 O O . ILE L 1 79 ? 70.083 20.604 59.185 1.00 74.84 ? 79 ILE L O 1 +ATOM 21557 C CB . ILE L 1 79 ? 72.925 19.926 58.768 1.00 65.77 ? 79 ILE L CB 1 +ATOM 21558 C CG1 . ILE L 1 79 ? 74.256 19.768 59.485 1.00 63.47 ? 79 ILE L CG1 1 +ATOM 21559 C CG2 . ILE L 1 79 ? 73.094 19.631 57.275 1.00 88.62 ? 79 ILE L CG2 1 +ATOM 21560 C CD1 . ILE L 1 79 ? 74.609 18.325 59.798 1.00 67.81 ? 79 ILE L CD1 1 +ATOM 21561 N N . PRO L 1 80 ? 70.598 22.069 57.515 1.00 41.49 ? 80 PRO L N 1 +ATOM 21562 C CA . PRO L 1 80 ? 69.205 21.992 57.146 1.00 48.49 ? 80 PRO L CA 1 +ATOM 21563 C C . PRO L 1 80 ? 69.027 20.898 56.114 1.00 51.67 ? 80 PRO L C 1 +ATOM 21564 O O . PRO L 1 80 ? 69.764 20.881 55.139 1.00 79.71 ? 80 PRO L O 1 +ATOM 21565 C CB . PRO L 1 80 ? 68.908 23.410 56.591 1.00 40.05 ? 80 PRO L CB 1 +ATOM 21566 C CG . PRO L 1 80 ? 69.898 24.274 57.240 1.00 36.00 ? 80 PRO L CG 1 +ATOM 21567 C CD . PRO L 1 80 ? 71.137 23.395 57.232 1.00 37.60 ? 80 PRO L CD 1 +ATOM 21568 N N . LEU L 1 81 ? 67.994 20.087 56.286 1.00 45.27 ? 81 LEU L N 1 +ATOM 21569 C CA . LEU L 1 81 ? 67.561 19.192 55.271 1.00 60.82 ? 81 LEU L CA 1 +ATOM 21570 C C . LEU L 1 81 ? 66.445 19.757 54.399 1.00 75.03 ? 81 LEU L C 1 +ATOM 21571 O O . LEU L 1 81 ? 65.610 20.555 54.880 1.00 77.82 ? 81 LEU L O 1 +ATOM 21572 C CB . LEU L 1 81 ? 67.095 17.927 55.914 1.00 70.88 ? 81 LEU L CB 1 +ATOM 21573 C CG . LEU L 1 81 ? 68.171 17.396 56.868 1.00 83.70 ? 81 LEU L CG 1 +ATOM 21574 C CD1 . LEU L 1 81 ? 67.596 16.190 57.566 1.00 95.89 ? 81 LEU L CD1 1 +ATOM 21575 C CD2 . LEU L 1 81 ? 69.418 17.013 56.117 1.00 87.38 ? 81 LEU L CD2 1 +ATOM 21576 N N . GLU L 1 82 ? 66.537 19.463 53.088 1.00 90.35 ? 82 GLU L N 1 +ATOM 21577 C CA . GLU L 1 82 ? 65.692 20.119 52.067 1.00 85.86 ? 82 GLU L CA 1 +ATOM 21578 C C . GLU L 1 82 ? 64.360 19.464 52.007 1.00 74.36 ? 82 GLU L C 1 +ATOM 21579 O O . GLU L 1 82 ? 64.245 18.299 51.585 1.00 78.13 ? 82 GLU L O 1 +ATOM 21580 C CB . GLU L 1 82 ? 66.330 20.128 50.664 1.00 85.06 ? 82 GLU L CB 1 +ATOM 21581 C CG . GLU L 1 82 ? 65.452 20.744 49.565 1.00 76.75 ? 82 GLU L CG 1 +ATOM 21582 C CD . GLU L 1 82 ? 65.257 22.273 49.660 1.00 92.90 ? 82 GLU L CD 1 +ATOM 21583 O OE1 . GLU L 1 82 ? 64.929 22.831 50.750 1.00 113.98 ? 82 GLU L OE1 1 +ATOM 21584 O OE2 . GLU L 1 82 ? 65.408 22.953 48.612 1.00 115.75 ? 82 GLU L OE2 1 +ATOM 21585 N N . ARG L 1 83 ? 63.359 20.199 52.504 1.00 80.28 ? 83 ARG L N 1 +ATOM 21586 C CA . ARG L 1 83 ? 61.971 19.750 52.472 1.00 84.52 ? 83 ARG L CA 1 +ATOM 21587 C C . ARG L 1 83 ? 61.053 20.753 51.761 1.00 76.85 ? 83 ARG L C 1 +ATOM 21588 O O . ARG L 1 83 ? 59.989 20.368 51.283 1.00 79.98 ? 83 ARG L O 1 +ATOM 21589 C CB . ARG L 1 83 ? 61.447 19.455 53.881 1.00 74.28 ? 83 ARG L CB 1 +ATOM 21590 C CG . ARG L 1 83 ? 62.271 18.441 54.664 1.00 73.93 ? 83 ARG L CG 1 +ATOM 21591 C CD . ARG L 1 83 ? 62.162 17.017 54.103 1.00 70.54 ? 83 ARG L CD 1 +ATOM 21592 N NE . ARG L 1 83 ? 62.773 16.065 55.033 1.00 58.64 ? 83 ARG L NE 1 +ATOM 21593 C CZ . ARG L 1 83 ? 63.992 15.555 54.932 1.00 51.82 ? 83 ARG L CZ 1 +ATOM 21594 N NH1 . ARG L 1 83 ? 64.755 15.816 53.885 1.00 61.42 ? 83 ARG L NH1 1 +ATOM 21595 N NH2 . ARG L 1 83 ? 64.470 14.830 55.920 1.00 48.87 ? 83 ARG L NH2 1 +ATOM 21596 N N . GLN L 1 84 ? 61.467 22.006 51.616 1.00 74.59 ? 84 GLN L N 1 +ATOM 21597 C CA . GLN L 1 84 ? 60.607 22.942 50.883 1.00 88.46 ? 84 GLN L CA 1 +ATOM 21598 C C . GLN L 1 84 ? 60.353 22.416 49.477 1.00 86.04 ? 84 GLN L C 1 +ATOM 21599 O O . GLN L 1 84 ? 59.249 22.495 48.954 1.00 92.15 ? 84 GLN L O 1 +ATOM 21600 C CB . GLN L 1 84 ? 61.159 24.377 50.867 1.00 89.00 ? 84 GLN L CB 1 +ATOM 21601 C CG . GLN L 1 84 ? 60.075 25.466 50.832 1.00 89.84 ? 84 GLN L CG 1 +ATOM 21602 C CD . GLN L 1 84 ? 60.658 26.871 50.743 1.00 135.96 ? 84 GLN L CD 1 +ATOM 21603 O OE1 . GLN L 1 84 ? 61.718 27.153 51.308 1.00 185.77 ? 84 GLN L OE1 1 +ATOM 21604 N NE2 . GLN L 1 84 ? 59.974 27.759 50.027 1.00 144.55 ? 84 GLN L NE2 1 +ATOM 21605 N N . GLY L 1 85 ? 61.376 21.876 48.847 1.00 86.87 ? 85 GLY L N 1 +ATOM 21606 C CA . GLY L 1 85 ? 61.195 21.397 47.496 1.00 87.10 ? 85 GLY L CA 1 +ATOM 21607 C C . GLY L 1 85 ? 61.356 19.895 47.466 1.00 61.06 ? 85 GLY L C 1 +ATOM 21608 O O . GLY L 1 85 ? 61.848 19.361 46.465 1.00 57.03 ? 85 GLY L O 1 +ATOM 21609 N N . LEU L 1 86 ? 60.771 19.221 48.452 1.00 49.78 ? 86 LEU L N 1 +ATOM 21610 C CA . LEU L 1 86 ? 60.943 17.775 48.601 1.00 54.58 ? 86 LEU L CA 1 +ATOM 21611 C C . LEU L 1 86 ? 60.466 16.985 47.375 1.00 88.49 ? 86 LEU L C 1 +ATOM 21612 O O . LEU L 1 86 ? 61.112 16.005 46.969 1.00 126.73 ? 86 LEU L O 1 +ATOM 21613 C CB . LEU L 1 86 ? 60.200 17.265 49.823 1.00 45.90 ? 86 LEU L CB 1 +ATOM 21614 C CG . LEU L 1 86 ? 60.147 15.786 50.082 1.00 55.07 ? 86 LEU L CG 1 +ATOM 21615 C CD1 . LEU L 1 86 ? 61.539 15.161 50.246 1.00 69.30 ? 86 LEU L CD1 1 +ATOM 21616 C CD2 . LEU L 1 86 ? 59.297 15.517 51.322 1.00 57.96 ? 86 LEU L CD2 1 +ATOM 21617 N N . GLN L 1 87 ? 59.395 17.455 46.725 1.00 91.67 ? 87 GLN L N 1 +ATOM 21618 C CA . GLN L 1 87 ? 58.822 16.729 45.599 1.00 84.80 ? 87 GLN L CA 1 +ATOM 21619 C C . GLN L 1 87 ? 59.812 16.585 44.405 1.00 100.95 ? 87 GLN L C 1 +ATOM 21620 O O . GLN L 1 87 ? 60.000 15.492 43.826 1.00 95.17 ? 87 GLN L O 1 +ATOM 21621 C CB . GLN L 1 87 ? 57.521 17.398 45.170 1.00 81.84 ? 87 GLN L CB 1 +ATOM 21622 C CG . GLN L 1 87 ? 56.464 16.411 44.662 1.00 92.31 ? 87 GLN L CG 1 +ATOM 21623 C CD . GLN L 1 87 ? 56.345 15.149 45.517 1.00 85.87 ? 87 GLN L CD 1 +ATOM 21624 O OE1 . GLN L 1 87 ? 56.096 15.224 46.721 1.00 130.04 ? 87 GLN L OE1 1 +ATOM 21625 N NE2 . GLN L 1 87 ? 56.518 13.983 44.897 1.00 88.32 ? 87 GLN L NE2 1 +ATOM 21626 N N . ASN L 1 88 ? 60.500 17.678 44.093 1.00 86.83 ? 88 ASN L N 1 +ATOM 21627 C CA . ASN L 1 88 ? 61.524 17.669 43.055 1.00 74.24 ? 88 ASN L CA 1 +ATOM 21628 C C . ASN L 1 88 ? 62.707 16.778 43.393 1.00 77.71 ? 88 ASN L C 1 +ATOM 21629 O O . ASN L 1 88 ? 63.309 16.137 42.505 1.00 85.17 ? 88 ASN L O 1 +ATOM 21630 C CB . ASN L 1 88 ? 62.050 19.072 42.858 1.00 65.86 ? 88 ASN L CB 1 +ATOM 21631 C CG . ASN L 1 88 ? 60.941 20.054 42.570 1.00 73.65 ? 88 ASN L CG 1 +ATOM 21632 O OD1 . ASN L 1 88 ? 60.003 19.721 41.848 1.00 67.78 ? 88 ASN L OD1 1 +ATOM 21633 N ND2 . ASN L 1 88 ? 61.068 21.283 43.084 1.00 61.71 ? 88 ASN L ND2 1 +ATOM 21634 N N . LEU L 1 89 ? 63.093 16.800 44.668 1.00 62.14 ? 89 LEU L N 1 +ATOM 21635 C CA . LEU L 1 89 ? 64.179 15.988 45.141 1.00 59.28 ? 89 LEU L CA 1 +ATOM 21636 C C . LEU L 1 89 ? 63.839 14.491 44.860 1.00 65.03 ? 89 LEU L C 1 +ATOM 21637 O O . LEU L 1 89 ? 64.678 13.695 44.384 1.00 62.40 ? 89 LEU L O 1 +ATOM 21638 C CB . LEU L 1 89 ? 64.386 16.264 46.617 1.00 64.86 ? 89 LEU L CB 1 +ATOM 21639 C CG . LEU L 1 89 ? 65.783 16.111 47.210 1.00 88.70 ? 89 LEU L CG 1 +ATOM 21640 C CD1 . LEU L 1 89 ? 65.810 14.985 48.245 1.00 96.75 ? 89 LEU L CD1 1 +ATOM 21641 C CD2 . LEU L 1 89 ? 66.845 15.862 46.147 1.00 78.86 ? 89 LEU L CD2 1 +ATOM 21642 N N . LEU L 1 90 ? 62.589 14.125 45.108 1.00 69.92 ? 90 LEU L N 1 +ATOM 21643 C CA . LEU L 1 90 ? 62.181 12.735 44.987 1.00 74.92 ? 90 LEU L CA 1 +ATOM 21644 C C . LEU L 1 90 ? 62.115 12.356 43.520 1.00 68.28 ? 90 LEU L C 1 +ATOM 21645 O O . LEU L 1 90 ? 62.320 11.178 43.144 1.00 50.34 ? 90 LEU L O 1 +ATOM 21646 C CB . LEU L 1 90 ? 60.825 12.522 45.675 1.00 69.47 ? 90 LEU L CB 1 +ATOM 21647 C CG . LEU L 1 90 ? 60.844 12.796 47.178 1.00 57.96 ? 90 LEU L CG 1 +ATOM 21648 C CD1 . LEU L 1 90 ? 59.410 12.995 47.628 1.00 65.06 ? 90 LEU L CD1 1 +ATOM 21649 C CD2 . LEU L 1 90 ? 61.521 11.647 47.925 1.00 49.84 ? 90 LEU L CD2 1 +ATOM 21650 N N . ASN L 1 91 ? 61.806 13.355 42.703 1.00 64.65 ? 91 ASN L N 1 +ATOM 21651 C CA . ASN L 1 91 ? 61.719 13.148 41.279 1.00 84.11 ? 91 ASN L CA 1 +ATOM 21652 C C . ASN L 1 91 ? 63.094 12.896 40.668 1.00 76.18 ? 91 ASN L C 1 +ATOM 21653 O O . ASN L 1 91 ? 63.277 11.921 39.904 1.00 57.71 ? 91 ASN L O 1 +ATOM 21654 C CB . ASN L 1 91 ? 61.061 14.350 40.615 1.00 102.80 ? 91 ASN L CB 1 +ATOM 21655 C CG . ASN L 1 91 ? 59.898 13.938 39.742 1.00 120.44 ? 91 ASN L CG 1 +ATOM 21656 O OD1 . ASN L 1 91 ? 59.052 13.156 40.198 1.00 124.98 ? 91 ASN L OD1 1 +ATOM 21657 N ND2 . ASN L 1 91 ? 59.985 14.238 38.429 1.00 126.05 ? 91 ASN L ND2 1 +ATOM 21658 N N . GLU L 1 92 ? 64.054 13.759 40.995 1.00 55.15 ? 92 GLU L N 1 +ATOM 21659 C CA . GLU L 1 92 ? 65.437 13.511 40.554 1.00 61.69 ? 92 GLU L CA 1 +ATOM 21660 C C . GLU L 1 92 ? 65.994 12.133 41.002 1.00 61.30 ? 92 GLU L C 1 +ATOM 21661 O O . GLU L 1 92 ? 66.710 11.452 40.253 1.00 42.31 ? 92 GLU L O 1 +ATOM 21662 C CB . GLU L 1 92 ? 66.378 14.587 41.055 1.00 61.59 ? 92 GLU L CB 1 +ATOM 21663 C CG . GLU L 1 92 ? 66.521 15.751 40.119 1.00 65.89 ? 92 GLU L CG 1 +ATOM 21664 C CD . GLU L 1 92 ? 66.896 15.336 38.682 1.00 76.31 ? 92 GLU L CD 1 +ATOM 21665 O OE1 . GLU L 1 92 ? 67.970 14.722 38.459 1.00 75.79 ? 92 GLU L OE1 1 +ATOM 21666 O OE2 . GLU L 1 92 ? 66.178 15.743 37.755 1.00 77.86 ? 92 GLU L OE2 1 +ATOM 21667 N N . ARG L 1 93 ? 65.595 11.709 42.197 1.00 61.18 ? 93 ARG L N 1 +ATOM 21668 C CA . ARG L 1 93 ? 65.950 10.390 42.675 1.00 69.00 ? 93 ARG L CA 1 +ATOM 21669 C C . ARG L 1 93 ? 65.244 9.247 41.870 1.00 77.28 ? 93 ARG L C 1 +ATOM 21670 O O . ARG L 1 93 ? 65.851 8.201 41.605 1.00 59.66 ? 93 ARG L O 1 +ATOM 21671 C CB . ARG L 1 93 ? 65.687 10.294 44.178 1.00 57.23 ? 93 ARG L CB 1 +ATOM 21672 C CG . ARG L 1 93 ? 66.615 11.174 44.944 1.00 51.88 ? 93 ARG L CG 1 +ATOM 21673 C CD . ARG L 1 93 ? 66.201 11.409 46.384 1.00 64.73 ? 93 ARG L CD 1 +ATOM 21674 N NE . ARG L 1 93 ? 66.964 10.587 47.327 1.00 71.07 ? 93 ARG L NE 1 +ATOM 21675 C CZ . ARG L 1 93 ? 66.598 9.397 47.764 1.00 61.94 ? 93 ARG L CZ 1 +ATOM 21676 N NH1 . ARG L 1 93 ? 65.427 8.864 47.408 1.00 56.55 ? 93 ARG L NH1 1 +ATOM 21677 N NH2 . ARG L 1 93 ? 67.390 8.777 48.628 1.00 64.14 ? 93 ARG L NH2 1 +ATOM 21678 N N . LYS L 1 94 ? 64.014 9.471 41.426 1.00 69.85 ? 94 LYS L N 1 +ATOM 21679 C CA . LYS L 1 94 ? 63.387 8.533 40.517 1.00 82.88 ? 94 LYS L CA 1 +ATOM 21680 C C . LYS L 1 94 ? 64.208 8.410 39.235 1.00 74.38 ? 94 LYS L C 1 +ATOM 21681 O O . LYS L 1 94 ? 64.338 7.308 38.663 1.00 62.12 ? 94 LYS L O 1 +ATOM 21682 C CB . LYS L 1 94 ? 61.965 8.981 40.173 1.00 110.82 ? 94 LYS L CB 1 +ATOM 21683 C CG . LYS L 1 94 ? 60.891 8.516 41.146 1.00 142.07 ? 94 LYS L CG 1 +ATOM 21684 C CD . LYS L 1 94 ? 59.561 9.187 40.819 1.00 162.66 ? 94 LYS L CD 1 +ATOM 21685 C CE . LYS L 1 94 ? 58.362 8.447 41.400 1.00 163.63 ? 94 LYS L CE 1 +ATOM 21686 N NZ . LYS L 1 94 ? 57.153 9.312 41.355 1.00 165.48 ? 94 LYS L NZ 1 +ATOM 21687 N N . ILE L 1 95 ? 64.680 9.551 38.728 1.00 65.88 ? 95 ILE L N 1 +ATOM 21688 C CA . ILE L 1 95 ? 65.343 9.568 37.419 1.00 65.23 ? 95 ILE L CA 1 +ATOM 21689 C C . ILE L 1 95 ? 66.697 8.909 37.488 1.00 56.77 ? 95 ILE L C 1 +ATOM 21690 O O . ILE L 1 95 ? 67.093 8.169 36.558 1.00 39.31 ? 95 ILE L O 1 +ATOM 21691 C CB . ILE L 1 95 ? 65.538 10.980 36.849 1.00 66.08 ? 95 ILE L CB 1 +ATOM 21692 C CG1 . ILE L 1 95 ? 64.233 11.785 36.903 1.00 56.77 ? 95 ILE L CG1 1 +ATOM 21693 C CG2 . ILE L 1 95 ? 65.968 10.846 35.393 1.00 97.67 ? 95 ILE L CG2 1 +ATOM 21694 C CD1 . ILE L 1 95 ? 64.220 13.049 36.060 1.00 53.12 ? 95 ILE L CD1 1 +ATOM 21695 N N . ILE L 1 96 ? 67.383 9.188 38.602 1.00 59.43 ? 96 ILE L N 1 +ATOM 21696 C CA . ILE L 1 96 ? 68.606 8.482 38.953 1.00 55.12 ? 96 ILE L CA 1 +ATOM 21697 C C . ILE L 1 96 ? 68.368 6.973 38.951 1.00 53.77 ? 96 ILE L C 1 +ATOM 21698 O O . ILE L 1 96 ? 69.023 6.252 38.194 1.00 74.43 ? 96 ILE L O 1 +ATOM 21699 C CB . ILE L 1 96 ? 69.184 8.898 40.313 1.00 41.29 ? 96 ILE L CB 1 +ATOM 21700 C CG1 . ILE L 1 96 ? 69.610 10.350 40.275 1.00 37.49 ? 96 ILE L CG1 1 +ATOM 21701 C CG2 . ILE L 1 96 ? 70.384 8.033 40.657 1.00 30.98 ? 96 ILE L CG2 1 +ATOM 21702 C CD1 . ILE L 1 96 ? 70.237 10.802 41.568 1.00 44.13 ? 96 ILE L CD1 1 +ATOM 21703 N N . ARG L 1 97 ? 67.438 6.506 39.768 1.00 51.24 ? 97 ARG L N 1 +ATOM 21704 C CA . ARG L 1 97 ? 67.221 5.060 39.924 1.00 78.21 ? 97 ARG L CA 1 +ATOM 21705 C C . ARG L 1 97 ? 66.807 4.404 38.606 1.00 84.13 ? 97 ARG L C 1 +ATOM 21706 O O . ARG L 1 97 ? 67.127 3.244 38.343 1.00 64.83 ? 97 ARG L O 1 +ATOM 21707 C CB . ARG L 1 97 ? 66.155 4.772 40.983 1.00 98.86 ? 97 ARG L CB 1 +ATOM 21708 C CG . ARG L 1 97 ? 66.701 4.296 42.325 1.00 100.16 ? 97 ARG L CG 1 +ATOM 21709 C CD . ARG L 1 97 ? 65.568 3.981 43.291 1.00 105.06 ? 97 ARG L CD 1 +ATOM 21710 N NE . ARG L 1 97 ? 65.034 5.183 43.938 1.00 101.92 ? 97 ARG L NE 1 +ATOM 21711 C CZ . ARG L 1 97 ? 65.395 5.623 45.145 1.00 114.81 ? 97 ARG L CZ 1 +ATOM 21712 N NH1 . ARG L 1 97 ? 66.304 4.953 45.875 1.00 105.60 ? 97 ARG L NH1 1 +ATOM 21713 N NH2 . ARG L 1 97 ? 64.852 6.748 45.628 1.00 102.62 ? 97 ARG L NH2 1 +ATOM 21714 N N . ALA L 1 98 ? 66.129 5.167 37.759 1.00 92.54 ? 98 ALA L N 1 +ATOM 21715 C CA . ALA L 1 98 ? 65.742 4.662 36.453 1.00 99.66 ? 98 ALA L CA 1 +ATOM 21716 C C . ALA L 1 98 ? 66.937 4.605 35.502 1.00 75.17 ? 98 ALA L C 1 +ATOM 21717 O O . ALA L 1 98 ? 66.988 3.772 34.590 1.00 43.27 ? 98 ALA L O 1 +ATOM 21718 C CB . ALA L 1 98 ? 64.642 5.533 35.879 1.00 119.68 ? 98 ALA L CB 1 +ATOM 21719 N N . ALA L 1 99 ? 67.902 5.487 35.745 1.00 78.31 ? 99 ALA L N 1 +ATOM 21720 C CA . ALA L 1 99 ? 69.113 5.561 34.926 1.00 97.92 ? 99 ALA L CA 1 +ATOM 21721 C C . ALA L 1 99 ? 70.001 4.333 35.128 1.00 86.24 ? 99 ALA L C 1 +ATOM 21722 O O . ALA L 1 99 ? 70.469 3.724 34.169 1.00 117.51 ? 99 ALA L O 1 +ATOM 21723 C CB . ALA L 1 99 ? 69.896 6.845 35.222 1.00 99.78 ? 99 ALA L CB 1 +ATOM 21724 N N . GLN L 1 100 ? 70.259 4.003 36.379 1.00 70.62 ? 100 GLN L N 1 +ATOM 21725 C CA . GLN L 1 100 ? 71.387 3.141 36.705 1.00 87.39 ? 100 GLN L CA 1 +ATOM 21726 C C . GLN L 1 100 ? 70.955 1.771 37.158 1.00 84.37 ? 100 GLN L C 1 +ATOM 21727 O O . GLN L 1 100 ? 71.793 0.966 37.597 1.00 138.51 ? 100 GLN L O 1 +ATOM 21728 C CB . GLN L 1 100 ? 72.323 3.795 37.760 1.00 89.48 ? 100 GLN L CB 1 +ATOM 21729 C CG . GLN L 1 100 ? 71.624 4.503 38.899 1.00 69.26 ? 100 GLN L CG 1 +ATOM 21730 C CD . GLN L 1 100 ? 72.455 5.615 39.493 1.00 52.20 ? 100 GLN L CD 1 +ATOM 21731 O OE1 . GLN L 1 100 ? 72.822 6.610 38.832 1.00 29.41 ? 100 GLN L OE1 1 +ATOM 21732 N NE2 . GLN L 1 100 ? 72.734 5.463 40.784 1.00 55.34 ? 100 GLN L NE2 1 +ATOM 21733 N N . GLU L 1 101 ? 69.666 1.495 37.054 1.00 80.65 ? 101 GLU L N 1 +ATOM 21734 C CA . GLU L 1 101 ? 69.138 0.210 37.527 1.00 100.96 ? 101 GLU L CA 1 +ATOM 21735 C C . GLU L 1 101 ? 69.619 -0.969 36.679 1.00 104.43 ? 101 GLU L C 1 +ATOM 21736 O O . GLU L 1 101 ? 69.661 -2.115 37.156 1.00 69.81 ? 101 GLU L O 1 +ATOM 21737 C CB . GLU L 1 101 ? 67.611 0.234 37.575 1.00 106.76 ? 101 GLU L CB 1 +ATOM 21738 C CG . GLU L 1 101 ? 66.944 0.700 36.290 1.00 99.09 ? 101 GLU L CG 1 +ATOM 21739 C CD . GLU L 1 101 ? 65.429 0.619 36.363 1.00 93.81 ? 101 GLU L CD 1 +ATOM 21740 O OE1 . GLU L 1 101 ? 64.892 0.531 37.480 1.00 111.47 ? 101 GLU L OE1 1 +ATOM 21741 O OE2 . GLU L 1 101 ? 64.765 0.651 35.305 1.00 117.98 ? 101 GLU L OE2 1 +ATOM 21742 N N . ASN L 1 102 ? 70.008 -0.689 35.436 1.00 104.60 ? 102 ASN L N 1 +ATOM 21743 C CA . ASN L 1 102 ? 70.453 -1.749 34.541 1.00 112.75 ? 102 ASN L CA 1 +ATOM 21744 C C . ASN L 1 102 ? 71.959 -2.010 34.573 1.00 123.89 ? 102 ASN L C 1 +ATOM 21745 O O . ASN L 1 102 ? 72.448 -2.896 33.878 1.00 116.97 ? 102 ASN L O 1 +ATOM 21746 C CB . ASN L 1 102 ? 70.009 -1.434 33.125 1.00 106.49 ? 102 ASN L CB 1 +ATOM 21747 C CG . ASN L 1 102 ? 68.513 -1.578 32.958 1.00 108.03 ? 102 ASN L CG 1 +ATOM 21748 O OD1 . ASN L 1 102 ? 67.991 -2.693 32.814 1.00 99.53 ? 102 ASN L OD1 1 +ATOM 21749 N ND2 . ASN L 1 102 ? 67.809 -0.452 33.008 1.00 97.58 ? 102 ASN L ND2 1 +ATOM 21750 N N . GLY L 1 103 ? 72.696 -1.223 35.350 1.00 131.18 ? 103 GLY L N 1 +ATOM 21751 C CA . GLY L 1 103 ? 74.150 -1.363 35.422 1.00 112.71 ? 103 GLY L CA 1 +ATOM 21752 C C . GLY L 1 103 ? 74.880 -1.162 34.103 1.00 116.24 ? 103 GLY L C 1 +ATOM 21753 O O . GLY L 1 103 ? 75.871 -1.838 33.809 1.00 158.08 ? 103 GLY L O 1 +ATOM 21754 N N . THR L 1 104 ? 74.353 -0.286 33.264 1.00 100.91 ? 104 THR L N 1 +ATOM 21755 C CA . THR L 1 104 ? 75.067 0.110 32.075 1.00 101.57 ? 104 THR L CA 1 +ATOM 21756 C C . THR L 1 104 ? 75.729 1.433 32.344 1.00 99.79 ? 104 THR L C 1 +ATOM 21757 O O . THR L 1 104 ? 76.724 1.745 31.715 1.00 115.24 ? 104 THR L O 1 +ATOM 21758 C CB . THR L 1 104 ? 74.150 0.186 30.823 1.00 128.32 ? 104 THR L CB 1 +ATOM 21759 O OG1 . THR L 1 104 ? 73.129 1.187 30.974 1.00 110.46 ? 104 THR L OG1 1 +ATOM 21760 C CG2 . THR L 1 104 ? 73.484 -1.176 30.565 1.00 148.84 ? 104 THR L CG2 1 +ATOM 21761 N N . VAL L 1 105 ? 75.163 2.235 33.250 1.00 97.63 ? 105 VAL L N 1 +ATOM 21762 C CA . VAL L 1 105 ? 75.590 3.649 33.385 1.00 110.99 ? 105 VAL L CA 1 +ATOM 21763 C C . VAL L 1 105 ? 77.063 3.687 33.790 1.00 139.62 ? 105 VAL L C 1 +ATOM 21764 O O . VAL L 1 105 ? 77.533 2.834 34.559 1.00 111.95 ? 105 VAL L O 1 +ATOM 21765 C CB . VAL L 1 105 ? 74.701 4.496 34.359 1.00 95.74 ? 105 VAL L CB 1 +ATOM 21766 C CG1 . VAL L 1 105 ? 75.533 5.502 35.148 1.00 94.75 ? 105 VAL L CG1 1 +ATOM 21767 C CG2 . VAL L 1 105 ? 73.571 5.219 33.607 1.00 65.42 ? 105 VAL L CG2 1 +ATOM 21768 N N . ALA L 1 106 ? 77.781 4.652 33.207 1.00 161.73 ? 106 ALA L N 1 +ATOM 21769 C CA . ALA L 1 106 ? 79.235 4.744 33.307 1.00 145.87 ? 106 ALA L CA 1 +ATOM 21770 C C . ALA L 1 106 ? 79.657 4.949 34.752 1.00 151.27 ? 106 ALA L C 1 +ATOM 21771 O O . ALA L 1 106 ? 79.078 5.773 35.461 1.00 183.45 ? 106 ALA L O 1 +ATOM 21772 C CB . ALA L 1 106 ? 79.745 5.884 32.433 1.00 124.86 ? 106 ALA L CB 1 +ATOM 21773 N N . ILE L 1 107 ? 80.659 4.183 35.182 1.00 155.51 ? 107 ILE L N 1 +ATOM 21774 C CA . ILE L 1 107 ? 81.092 4.164 36.584 1.00 143.91 ? 107 ILE L CA 1 +ATOM 21775 C C . ILE L 1 107 ? 81.510 5.557 37.107 1.00 134.16 ? 107 ILE L C 1 +ATOM 21776 O O . ILE L 1 107 ? 81.341 5.867 38.287 1.00 108.34 ? 107 ILE L O 1 +ATOM 21777 C CB . ILE L 1 107 ? 82.244 3.142 36.787 1.00 140.67 ? 107 ILE L CB 1 +ATOM 21778 C CG1 . ILE L 1 107 ? 82.494 2.878 38.277 1.00 126.20 ? 107 ILE L CG1 1 +ATOM 21779 C CG2 . ILE L 1 107 ? 83.522 3.617 36.101 1.00 133.83 ? 107 ILE L CG2 1 +ATOM 21780 C CD1 . ILE L 1 107 ? 81.281 2.375 39.036 1.00 119.40 ? 107 ILE L CD1 1 +ATOM 21781 N N . ASN L 1 108 ? 82.041 6.394 36.221 1.00 141.85 ? 108 ASN L N 1 +ATOM 21782 C CA . ASN L 1 108 ? 82.378 7.783 36.556 1.00 138.44 ? 108 ASN L CA 1 +ATOM 21783 C C . ASN L 1 108 ? 81.123 8.621 36.770 1.00 141.20 ? 108 ASN L C 1 +ATOM 21784 O O . ASN L 1 108 ? 81.099 9.533 37.593 1.00 133.67 ? 108 ASN L O 1 +ATOM 21785 C CB . ASN L 1 108 ? 83.206 8.416 35.433 1.00 151.61 ? 108 ASN L CB 1 +ATOM 21786 C CG . ASN L 1 108 ? 84.060 7.402 34.697 1.00 182.09 ? 108 ASN L CG 1 +ATOM 21787 O OD1 . ASN L 1 108 ? 85.186 7.113 35.103 1.00 192.85 ? 108 ASN L OD1 1 +ATOM 21788 N ND2 . ASN L 1 108 ? 83.530 6.862 33.599 1.00 198.36 ? 108 ASN L ND2 1 +ATOM 21789 N N . ASN L 1 109 ? 80.095 8.323 35.984 1.00 139.07 ? 109 ASN L N 1 +ATOM 21790 C CA . ASN L 1 109 ? 78.864 9.097 35.967 1.00 119.19 ? 109 ASN L CA 1 +ATOM 21791 C C . ASN L 1 109 ? 77.856 8.653 37.024 1.00 109.07 ? 109 ASN L C 1 +ATOM 21792 O O . ASN L 1 109 ? 76.930 9.400 37.356 1.00 148.04 ? 109 ASN L O 1 +ATOM 21793 C CB . ASN L 1 109 ? 78.219 9.006 34.589 1.00 125.99 ? 109 ASN L CB 1 +ATOM 21794 C CG . ASN L 1 109 ? 78.153 10.351 33.899 1.00 151.38 ? 109 ASN L CG 1 +ATOM 21795 O OD1 . ASN L 1 109 ? 77.071 10.882 33.650 1.00 150.17 ? 109 ASN L OD1 1 +ATOM 21796 N ND2 . ASN L 1 109 ? 79.317 10.919 33.596 1.00 173.05 ? 109 ASN L ND2 1 +ATOM 21797 N N . ARG L 1 110 ? 78.060 7.452 37.560 1.00 89.72 ? 110 ARG L N 1 +ATOM 21798 C CA . ARG L 1 110 ? 77.145 6.827 38.509 1.00 69.50 ? 110 ARG L CA 1 +ATOM 21799 C C . ARG L 1 110 ? 76.899 7.728 39.719 1.00 72.45 ? 110 ARG L C 1 +ATOM 21800 O O . ARG L 1 110 ? 77.830 8.286 40.307 1.00 68.86 ? 110 ARG L O 1 +ATOM 21801 C CB . ARG L 1 110 ? 77.751 5.495 38.996 1.00 83.45 ? 110 ARG L CB 1 +ATOM 21802 C CG . ARG L 1 110 ? 76.748 4.474 39.503 1.00 99.51 ? 110 ARG L CG 1 +ATOM 21803 C CD . ARG L 1 110 ? 77.160 3.042 39.175 1.00 101.60 ? 110 ARG L CD 1 +ATOM 21804 N NE . ARG L 1 110 ? 77.997 2.433 40.212 1.00 108.76 ? 110 ARG L NE 1 +ATOM 21805 C CZ . ARG L 1 110 ? 77.685 1.324 40.905 1.00 122.48 ? 110 ARG L CZ 1 +ATOM 21806 N NH1 . ARG L 1 110 ? 76.541 0.665 40.683 1.00 107.11 ? 110 ARG L NH1 1 +ATOM 21807 N NH2 . ARG L 1 110 ? 78.534 0.860 41.823 1.00 100.13 ? 110 ARG L NH2 1 +ATOM 21808 N N . ILE L 1 111 ? 75.639 7.846 40.127 1.00 91.49 ? 111 ILE L N 1 +ATOM 21809 C CA . ILE L 1 111 ? 75.287 8.583 41.372 1.00 85.86 ? 111 ILE L CA 1 +ATOM 21810 C C . ILE L 1 111 ? 74.834 7.590 42.432 1.00 81.00 ? 111 ILE L C 1 +ATOM 21811 O O . ILE L 1 111 ? 73.806 6.957 42.244 1.00 91.80 ? 111 ILE L O 1 +ATOM 21812 C CB . ILE L 1 111 ? 74.157 9.628 41.152 1.00 70.64 ? 111 ILE L CB 1 +ATOM 21813 C CG1 . ILE L 1 111 ? 74.653 10.690 40.179 1.00 80.67 ? 111 ILE L CG1 1 +ATOM 21814 C CG2 . ILE L 1 111 ? 73.757 10.262 42.463 1.00 53.56 ? 111 ILE L CG2 1 +ATOM 21815 C CD1 . ILE L 1 111 ? 73.575 11.601 39.636 1.00 70.04 ? 111 ILE L CD1 1 +ATOM 21816 N N . PRO L 1 112 ? 75.579 7.480 43.549 1.00 81.53 ? 112 PRO L N 1 +ATOM 21817 C CA . PRO L 1 112 ? 75.232 6.529 44.595 1.00 77.96 ? 112 PRO L CA 1 +ATOM 21818 C C . PRO L 1 112 ? 74.128 7.085 45.489 1.00 91.84 ? 112 PRO L C 1 +ATOM 21819 O O . PRO L 1 112 ? 74.195 8.257 45.914 1.00 83.42 ? 112 PRO L O 1 +ATOM 21820 C CB . PRO L 1 112 ? 76.519 6.396 45.378 1.00 72.82 ? 112 PRO L CB 1 +ATOM 21821 C CG . PRO L 1 112 ? 77.165 7.748 45.248 1.00 87.39 ? 112 PRO L CG 1 +ATOM 21822 C CD . PRO L 1 112 ? 76.713 8.342 43.940 1.00 89.08 ? 112 PRO L CD 1 +ATOM 21823 N N . LEU L 1 113 ? 73.071 6.289 45.665 1.00 102.37 ? 113 LEU L N 1 +ATOM 21824 C CA . LEU L 1 113 ? 71.853 6.753 46.325 1.00 91.99 ? 113 LEU L CA 1 +ATOM 21825 C C . LEU L 1 113 ? 71.711 6.141 47.685 1.00 98.91 ? 113 LEU L C 1 +ATOM 21826 O O . LEU L 1 113 ? 71.968 4.945 47.909 1.00 88.71 ? 113 LEU L O 1 +ATOM 21827 C CB . LEU L 1 113 ? 70.597 6.452 45.513 1.00 82.99 ? 113 LEU L CB 1 +ATOM 21828 C CG . LEU L 1 113 ? 70.213 7.506 44.484 1.00 85.76 ? 113 LEU L CG 1 +ATOM 21829 C CD1 . LEU L 1 113 ? 68.916 7.083 43.854 1.00 97.79 ? 113 LEU L CD1 1 +ATOM 21830 C CD2 . LEU L 1 113 ? 70.084 8.900 45.061 1.00 86.13 ? 113 LEU L CD2 1 +ATOM 21831 N N . GLN L 1 114 ? 71.274 6.997 48.589 1.00 97.92 ? 114 GLN L N 1 +ATOM 21832 C CA . GLN L 1 114 ? 71.327 6.721 49.997 1.00 90.86 ? 114 GLN L CA 1 +ATOM 21833 C C . GLN L 1 114 ? 70.050 7.322 50.512 1.00 78.36 ? 114 GLN L C 1 +ATOM 21834 O O . GLN L 1 114 ? 69.538 8.280 49.935 1.00 60.36 ? 114 GLN L O 1 +ATOM 21835 C CB . GLN L 1 114 ? 72.546 7.395 50.643 1.00 87.44 ? 114 GLN L CB 1 +ATOM 21836 C CG . GLN L 1 114 ? 73.131 6.630 51.826 1.00 82.38 ? 114 GLN L CG 1 +ATOM 21837 C CD . GLN L 1 114 ? 74.009 7.488 52.751 1.00 91.93 ? 114 GLN L CD 1 +ATOM 21838 O OE1 . GLN L 1 114 ? 74.297 7.139 53.936 1.00 86.20 ? 114 GLN L OE1 1 +ATOM 21839 N NE2 . GLN L 1 114 ? 74.438 8.633 52.222 1.00 81.12 ? 114 GLN L NE2 1 +ATOM 21840 N N . SER L 1 115 ? 69.516 6.714 51.567 1.00 77.03 ? 115 SER L N 1 +ATOM 21841 C CA . SER L 1 115 ? 68.201 7.075 52.083 1.00 69.60 ? 115 SER L CA 1 +ATOM 21842 C C . SER L 1 115 ? 68.233 8.516 52.515 1.00 65.24 ? 115 SER L C 1 +ATOM 21843 O O . SER L 1 115 ? 69.334 9.074 52.744 1.00 66.79 ? 115 SER L O 1 +ATOM 21844 C CB . SER L 1 115 ? 67.834 6.197 53.268 1.00 75.70 ? 115 SER L CB 1 +ATOM 21845 O OG . SER L 1 115 ? 68.898 6.172 54.237 1.00 80.58 ? 115 SER L OG 1 +ATOM 21846 N N . LEU L 1 116 ? 67.066 9.164 52.544 1.00 63.20 ? 116 LEU L N 1 +ATOM 21847 C CA . LEU L 1 116 ? 67.095 10.609 52.655 1.00 72.38 ? 116 LEU L CA 1 +ATOM 21848 C C . LEU L 1 116 ? 67.448 10.920 54.096 1.00 83.08 ? 116 LEU L C 1 +ATOM 21849 O O . LEU L 1 116 ? 66.838 10.321 54.970 1.00 88.56 ? 116 LEU L O 1 +ATOM 21850 C CB . LEU L 1 116 ? 65.764 11.219 52.286 1.00 60.72 ? 116 LEU L CB 1 +ATOM 21851 C CG . LEU L 1 116 ? 65.345 11.148 50.812 1.00 62.06 ? 116 LEU L CG 1 +ATOM 21852 C CD1 . LEU L 1 116 ? 64.448 9.934 50.577 1.00 66.80 ? 116 LEU L CD1 1 +ATOM 21853 C CD2 . LEU L 1 116 ? 64.621 12.442 50.438 1.00 63.54 ? 116 LEU L CD2 1 +ATOM 21854 N N . THR L 1 117 ? 68.501 11.727 54.322 1.00 68.08 ? 117 THR L N 1 +ATOM 21855 C CA . THR L 1 117 ? 68.971 12.062 55.672 1.00 60.45 ? 117 THR L CA 1 +ATOM 21856 C C . THR L 1 117 ? 67.840 12.674 56.418 1.00 61.20 ? 117 THR L C 1 +ATOM 21857 O O . THR L 1 117 ? 67.083 13.479 55.851 1.00 42.77 ? 117 THR L O 1 +ATOM 21858 C CB . THR L 1 117 ? 70.068 13.117 55.666 1.00 69.14 ? 117 THR L CB 1 +ATOM 21859 O OG1 . THR L 1 117 ? 71.140 12.667 54.835 1.00 129.59 ? 117 THR L OG1 1 +ATOM 21860 C CG2 . THR L 1 117 ? 70.587 13.346 57.056 1.00 75.96 ? 117 THR L CG2 1 +ATOM 21861 N N . ALA L 1 118 ? 67.616 12.171 57.635 1.00 73.99 ? 118 ALA L N 1 +ATOM 21862 C CA . ALA L 1 118 ? 66.369 12.457 58.368 1.00 85.81 ? 118 ALA L CA 1 +ATOM 21863 C C . ALA L 1 118 ? 66.612 13.274 59.606 1.00 60.15 ? 118 ALA L C 1 +ATOM 21864 O O . ALA L 1 118 ? 67.554 12.995 60.348 1.00 52.11 ? 118 ALA L O 1 +ATOM 21865 C CB . ALA L 1 118 ? 65.645 11.172 58.754 1.00 116.30 ? 118 ALA L CB 1 +ATOM 21866 N N . ALA L 1 119 ? 65.704 14.218 59.840 1.00 43.25 ? 119 ALA L N 1 +ATOM 21867 C CA . ALA L 1 119 ? 65.858 15.199 60.888 1.00 54.04 ? 119 ALA L CA 1 +ATOM 21868 C C . ALA L 1 119 ? 65.332 14.686 62.220 1.00 77.76 ? 119 ALA L C 1 +ATOM 21869 O O . ALA L 1 119 ? 64.426 13.822 62.258 1.00 65.36 ? 119 ALA L O 1 +ATOM 21870 C CB . ALA L 1 119 ? 65.131 16.465 60.507 1.00 55.28 ? 119 ALA L CB 1 +ATOM 21871 N N . ASN L 1 120 ? 65.848 15.243 63.325 1.00 98.97 ? 120 ASN L N 1 +ATOM 21872 C CA . ASN L 1 120 ? 65.296 14.915 64.655 1.00 122.55 ? 120 ASN L CA 1 +ATOM 21873 C C . ASN L 1 120 ? 64.293 15.953 65.140 1.00 87.09 ? 120 ASN L C 1 +ATOM 21874 O O . ASN L 1 120 ? 63.248 15.621 65.709 1.00 74.07 ? 120 ASN L O 1 +ATOM 21875 C CB . ASN L 1 120 ? 66.408 14.741 65.710 1.00 132.91 ? 120 ASN L CB 1 +ATOM 21876 C CG . ASN L 1 120 ? 65.863 14.403 67.106 1.00 131.15 ? 120 ASN L CG 1 +ATOM 21877 O OD1 . ASN L 1 120 ? 64.855 13.684 67.255 1.00 121.27 ? 120 ASN L OD1 1 +ATOM 21878 N ND2 . ASN L 1 120 ? 66.528 14.933 68.133 1.00 109.70 ? 120 ASN L ND2 1 +ATOM 21879 N N . ILE L 1 121 ? 64.669 17.212 65.014 1.00 65.37 ? 121 ILE L N 1 +ATOM 21880 C CA . ILE L 1 121 ? 63.762 18.280 65.382 1.00 59.79 ? 121 ILE L CA 1 +ATOM 21881 C C . ILE L 1 121 ? 63.401 18.933 64.106 1.00 48.98 ? 121 ILE L C 1 +ATOM 21882 O O . ILE L 1 121 ? 64.241 19.111 63.234 1.00 66.31 ? 121 ILE L O 1 +ATOM 21883 C CB . ILE L 1 121 ? 64.370 19.287 66.419 1.00 58.72 ? 121 ILE L CB 1 +ATOM 21884 C CG1 . ILE L 1 121 ? 65.446 20.177 65.815 1.00 46.41 ? 121 ILE L CG1 1 +ATOM 21885 C CG2 . ILE L 1 121 ? 64.928 18.532 67.644 1.00 76.57 ? 121 ILE L CG2 1 +ATOM 21886 C CD1 . ILE L 1 121 ? 65.015 21.596 65.681 1.00 39.30 ? 121 ILE L CD1 1 +ATOM 21887 N N . MET L 1 122 ? 62.152 19.277 63.973 1.00 45.67 ? 122 MET L N 1 +ATOM 21888 C CA . MET L 1 122 ? 61.808 20.210 62.944 1.00 66.95 ? 122 MET L CA 1 +ATOM 21889 C C . MET L 1 122 ? 61.201 21.504 63.521 1.00 67.97 ? 122 MET L C 1 +ATOM 21890 O O . MET L 1 122 ? 60.593 21.500 64.579 1.00 128.54 ? 122 MET L O 1 +ATOM 21891 C CB . MET L 1 122 ? 60.879 19.540 61.946 1.00 81.39 ? 122 MET L CB 1 +ATOM 21892 C CG . MET L 1 122 ? 59.590 19.003 62.531 1.00 120.08 ? 122 MET L CG 1 +ATOM 21893 S SD . MET L 1 122 ? 58.318 18.891 61.239 1.00 100.51 ? 122 MET L SD 1 +ATOM 21894 C CE . MET L 1 122 ? 56.917 19.562 62.197 1.00 152.27 ? 122 MET L CE 1 +ATOM 21895 N N . VAL L 1 123 ? 61.514 22.635 62.896 1.00 62.89 ? 123 VAL L N 1 +ATOM 21896 C CA . VAL L 1 123 ? 61.082 23.943 63.383 1.00 50.83 ? 123 VAL L CA 1 +ATOM 21897 C C . VAL L 1 123 ? 60.169 24.535 62.375 1.00 49.96 ? 123 VAL L C 1 +ATOM 21898 O O . VAL L 1 123 ? 60.570 24.753 61.229 1.00 52.04 ? 123 VAL L O 1 +ATOM 21899 C CB . VAL L 1 123 ? 62.274 24.944 63.676 1.00 37.06 ? 123 VAL L CB 1 +ATOM 21900 C CG1 . VAL L 1 123 ? 63.359 24.816 62.652 1.00 31.22 ? 123 VAL L CG1 1 +ATOM 21901 C CG2 . VAL L 1 123 ? 61.783 26.383 63.825 1.00 26.13 ? 123 VAL L CG2 1 +ATOM 21902 N N . GLU L 1 124 ? 58.967 24.872 62.818 1.00 55.24 ? 124 GLU L N 1 +ATOM 21903 C CA . GLU L 1 124 ? 58.084 25.684 61.994 1.00 75.21 ? 124 GLU L CA 1 +ATOM 21904 C C . GLU L 1 124 ? 57.584 26.922 62.709 1.00 75.16 ? 124 GLU L C 1 +ATOM 21905 O O . GLU L 1 124 ? 57.849 27.120 63.882 1.00 94.64 ? 124 GLU L O 1 +ATOM 21906 C CB . GLU L 1 124 ? 56.894 24.868 61.541 1.00 72.77 ? 124 GLU L CB 1 +ATOM 21907 C CG . GLU L 1 124 ? 56.483 23.790 62.500 1.00 60.78 ? 124 GLU L CG 1 +ATOM 21908 C CD . GLU L 1 124 ? 55.602 22.782 61.812 1.00 75.77 ? 124 GLU L CD 1 +ATOM 21909 O OE1 . GLU L 1 124 ? 55.826 22.478 60.625 1.00 64.05 ? 124 GLU L OE1 1 +ATOM 21910 O OE2 . GLU L 1 124 ? 54.649 22.301 62.452 1.00 127.93 ? 124 GLU L OE2 1 +ATOM 21911 N N . GLY L 1 125 ? 56.964 27.817 61.945 1.00 78.44 ? 125 GLY L N 1 +ATOM 21912 C CA . GLY L 1 125 ? 56.560 29.096 62.471 1.00 89.28 ? 125 GLY L CA 1 +ATOM 21913 C C . GLY L 1 125 ? 55.715 29.857 61.486 1.00 88.84 ? 125 GLY L C 1 +ATOM 21914 O O . GLY L 1 125 ? 55.114 29.276 60.573 1.00 112.64 ? 125 GLY L O 1 +ATOM 21915 N N . SER L 1 126 ? 55.609 31.162 61.696 1.00 64.18 ? 126 SER L N 1 +ATOM 21916 C CA . SER L 1 126 ? 54.638 31.938 60.949 1.00 73.63 ? 126 SER L CA 1 +ATOM 21917 C C . SER L 1 126 ? 54.992 33.370 61.077 1.00 63.51 ? 126 SER L C 1 +ATOM 21918 O O . SER L 1 126 ? 55.451 33.805 62.123 1.00 74.81 ? 126 SER L O 1 +ATOM 21919 C CB . SER L 1 126 ? 53.177 31.726 61.448 1.00 87.86 ? 126 SER L CB 1 +ATOM 21920 O OG . SER L 1 126 ? 52.929 30.414 61.990 1.00 75.13 ? 126 SER L OG 1 +ATOM 21921 N N . ILE L 1 127 ? 54.721 34.137 60.038 1.00 74.67 ? 127 ILE L N 1 +ATOM 21922 C CA . ILE L 1 127 ? 54.726 35.580 60.191 1.00 91.12 ? 127 ILE L CA 1 +ATOM 21923 C C . ILE L 1 127 ? 53.391 35.916 60.840 1.00 81.91 ? 127 ILE L C 1 +ATOM 21924 O O . ILE L 1 127 ? 52.379 36.015 60.173 1.00 103.56 ? 127 ILE L O 1 +ATOM 21925 C CB . ILE L 1 127 ? 54.943 36.346 58.851 1.00 92.10 ? 127 ILE L CB 1 +ATOM 21926 C CG1 . ILE L 1 127 ? 56.343 36.050 58.283 1.00 93.80 ? 127 ILE L CG1 1 +ATOM 21927 C CG2 . ILE L 1 127 ? 54.759 37.855 59.044 1.00 71.51 ? 127 ILE L CG2 1 +ATOM 21928 C CD1 . ILE L 1 127 ? 56.413 36.068 56.772 1.00 94.67 ? 127 ILE L CD1 1 +ATOM 21929 N N . ILE L 1 128 ? 53.439 36.185 62.132 1.00 79.44 ? 128 ILE L N 1 +ATOM 21930 C CA . ILE L 1 128 ? 52.280 36.615 62.900 1.00 75.19 ? 128 ILE L CA 1 +ATOM 21931 C C . ILE L 1 128 ? 52.271 38.153 62.894 1.00 94.28 ? 128 ILE L C 1 +ATOM 21932 O O . ILE L 1 128 ? 53.105 38.848 63.507 1.00 106.42 ? 128 ILE L O 1 +ATOM 21933 C CB . ILE L 1 128 ? 52.372 36.052 64.320 1.00 78.95 ? 128 ILE L CB 1 +ATOM 21934 C CG1 . ILE L 1 128 ? 53.716 36.412 64.992 1.00 70.08 ? 128 ILE L CG1 1 +ATOM 21935 C CG2 . ILE L 1 128 ? 52.358 34.544 64.273 1.00 99.38 ? 128 ILE L CG2 1 +ATOM 21936 C CD1 . ILE L 1 128 ? 53.650 36.407 66.510 1.00 63.04 ? 128 ILE L CD1 1 +ATOM 21937 N N . GLY L 1 129 ? 51.463 38.694 62.010 1.00 114.68 ? 129 GLY L N 1 +ATOM 21938 C CA . GLY L 1 129 ? 51.181 40.118 62.062 1.00 133.21 ? 129 GLY L CA 1 +ATOM 21939 C C . GLY L 1 129 ? 52.125 41.085 61.355 1.00 124.86 ? 129 GLY L C 1 +ATOM 21940 O O . GLY L 1 129 ? 53.360 41.009 61.446 1.00 103.06 ? 129 GLY L O 1 +ATOM 21941 N N . TYR L 1 130 ? 51.501 42.022 60.653 1.00 126.35 ? 130 TYR L N 1 +ATOM 21942 C CA . TYR L 1 130 ? 52.152 43.243 60.216 1.00 118.25 ? 130 TYR L CA 1 +ATOM 21943 C C . TYR L 1 130 ? 51.124 44.340 60.410 1.00 96.18 ? 130 TYR L C 1 +ATOM 21944 O O . TYR L 1 130 ? 50.137 44.384 59.730 1.00 102.36 ? 130 TYR L O 1 +ATOM 21945 C CB . TYR L 1 130 ? 52.565 43.127 58.741 1.00 114.33 ? 130 TYR L CB 1 +ATOM 21946 C CG . TYR L 1 130 ? 53.153 44.385 58.114 1.00 98.40 ? 130 TYR L CG 1 +ATOM 21947 C CD1 . TYR L 1 130 ? 52.360 45.490 57.835 1.00 98.82 ? 130 TYR L CD1 1 +ATOM 21948 C CD2 . TYR L 1 130 ? 54.494 44.432 57.733 1.00 94.45 ? 130 TYR L CD2 1 +ATOM 21949 C CE1 . TYR L 1 130 ? 52.895 46.625 57.236 1.00 104.25 ? 130 TYR L CE1 1 +ATOM 21950 C CE2 . TYR L 1 130 ? 55.034 45.556 57.134 1.00 101.95 ? 130 TYR L CE2 1 +ATOM 21951 C CZ . TYR L 1 130 ? 54.233 46.652 56.893 1.00 101.88 ? 130 TYR L CZ 1 +ATOM 21952 O OH . TYR L 1 130 ? 54.795 47.766 56.313 1.00 101.43 ? 130 TYR L OH 1 +ATOM 21953 N N . GLU L 1 131 ? 51.333 45.186 61.398 1.00 91.34 ? 131 GLU L N 1 +ATOM 21954 C CA . GLU L 1 131 ? 50.528 46.391 61.543 1.00 82.72 ? 131 GLU L CA 1 +ATOM 21955 C C . GLU L 1 131 ? 51.275 47.562 60.929 1.00 73.15 ? 131 GLU L C 1 +ATOM 21956 O O . GLU L 1 131 ? 52.509 47.594 60.943 1.00 69.64 ? 131 GLU L O 1 +ATOM 21957 C CB . GLU L 1 131 ? 50.248 46.633 63.027 1.00 110.94 ? 131 GLU L CB 1 +ATOM 21958 C CG . GLU L 1 131 ? 49.231 47.713 63.339 1.00 100.16 ? 131 GLU L CG 1 +ATOM 21959 C CD . GLU L 1 131 ? 47.786 47.203 63.333 1.00 111.89 ? 131 GLU L CD 1 +ATOM 21960 O OE1 . GLU L 1 131 ? 47.557 46.001 63.619 1.00 126.09 ? 131 GLU L OE1 1 +ATOM 21961 O OE2 . GLU L 1 131 ? 46.874 48.022 63.074 1.00 97.37 ? 131 GLU L OE2 1 +ATOM 21962 N N . SER L 1 132 ? 50.538 48.513 60.374 1.00 89.13 ? 132 SER L N 1 +ATOM 21963 C CA . SER L 1 132 ? 51.148 49.585 59.597 1.00 104.05 ? 132 SER L CA 1 +ATOM 21964 C C . SER L 1 132 ? 50.883 50.972 60.196 1.00 111.43 ? 132 SER L C 1 +ATOM 21965 O O . SER L 1 132 ? 49.775 51.261 60.658 1.00 150.60 ? 132 SER L O 1 +ATOM 21966 C CB . SER L 1 132 ? 50.652 49.516 58.150 1.00 100.67 ? 132 SER L CB 1 +ATOM 21967 O OG . SER L 1 132 ? 49.851 50.640 57.830 1.00 126.34 ? 132 SER L OG 1 +ATOM 21968 N N . ASN L 1 133 ? 51.889 51.842 60.134 1.00 102.89 ? 133 ASN L N 1 +ATOM 21969 C CA . ASN L 1 133 ? 51.853 53.133 60.832 1.00 117.02 ? 133 ASN L CA 1 +ATOM 21970 C C . ASN L 1 133 ? 51.389 52.949 62.268 1.00 130.63 ? 133 ASN L C 1 +ATOM 21971 O O . ASN L 1 133 ? 50.435 53.589 62.719 1.00 147.77 ? 133 ASN L O 1 +ATOM 21972 C CB . ASN L 1 133 ? 50.954 54.149 60.120 1.00 98.33 ? 133 ASN L CB 1 +ATOM 21973 C CG . ASN L 1 133 ? 51.421 54.434 58.702 1.00 100.48 ? 133 ASN L CG 1 +ATOM 21974 O OD1 . ASN L 1 133 ? 52.618 54.385 58.388 1.00 108.40 ? 133 ASN L OD1 1 +ATOM 21975 N ND2 . ASN L 1 133 ? 50.477 54.728 57.839 1.00 110.63 ? 133 ASN L ND2 1 +ATOM 21976 N N . VAL L 1 134 ? 52.121 52.108 62.987 1.00 129.74 ? 134 VAL L N 1 +ATOM 21977 C CA . VAL L 1 134 ? 51.862 51.856 64.396 1.00 117.72 ? 134 VAL L CA 1 +ATOM 21978 C C . VAL L 1 134 ? 52.190 53.137 65.177 1.00 97.34 ? 134 VAL L C 1 +ATOM 21979 O O . VAL L 1 134 ? 51.495 53.492 66.128 1.00 68.92 ? 134 VAL L O 1 +ATOM 21980 C CB . VAL L 1 134 ? 52.711 50.670 64.907 1.00 120.76 ? 134 VAL L CB 1 +ATOM 21981 C CG1 . VAL L 1 134 ? 52.379 50.344 66.345 1.00 111.57 ? 134 VAL L CG1 1 +ATOM 21982 C CG2 . VAL L 1 134 ? 52.488 49.442 64.030 1.00 123.83 ? 134 VAL L CG2 1 +ATOM 21983 N N . LYS L 1 135 ? 53.208 53.860 64.716 1.00 90.71 ? 135 LYS L N 1 +ATOM 21984 C CA . LYS L 1 135 ? 53.400 55.249 65.124 1.00 92.39 ? 135 LYS L CA 1 +ATOM 21985 C C . LYS L 1 135 ? 53.751 56.134 63.949 1.00 96.62 ? 135 LYS L C 1 +ATOM 21986 O O . LYS L 1 135 ? 54.240 55.661 62.900 1.00 93.58 ? 135 LYS L O 1 +ATOM 21987 C CB . LYS L 1 135 ? 54.518 55.348 66.158 1.00 111.60 ? 135 LYS L CB 1 +ATOM 21988 C CG . LYS L 1 135 ? 54.224 54.602 67.448 1.00 123.48 ? 135 LYS L CG 1 +ATOM 21989 C CD . LYS L 1 135 ? 55.421 54.646 68.384 1.00 118.85 ? 135 LYS L CD 1 +ATOM 21990 C CE . LYS L 1 135 ? 55.152 53.900 69.677 1.00 133.44 ? 135 LYS L CE 1 +ATOM 21991 N NZ . LYS L 1 135 ? 56.081 54.343 70.744 1.00 131.50 ? 135 LYS L NZ 1 +ATOM 21992 N N . SER L 1 136 ? 53.542 57.435 64.137 1.00 113.38 ? 136 SER L N 1 +ATOM 21993 C CA . SER L 1 136 ? 53.865 58.422 63.103 1.00 132.43 ? 136 SER L CA 1 +ATOM 21994 C C . SER L 1 136 ? 53.942 59.844 63.666 1.00 104.84 ? 136 SER L C 1 +ATOM 21995 O O . SER L 1 136 ? 53.334 60.135 64.686 1.00 85.31 ? 136 SER L O 1 +ATOM 21996 C CB . SER L 1 136 ? 52.850 58.351 61.952 1.00 125.20 ? 136 SER L CB 1 +ATOM 21997 O OG . SER L 1 136 ? 52.266 59.623 61.701 1.00 140.38 ? 136 SER L OG 1 +ATOM 21998 N N . GLY L 1 137 ? 54.704 60.710 62.994 1.00 91.65 ? 137 GLY L N 1 +ATOM 21999 C CA . GLY L 1 137 ? 54.804 62.107 63.398 1.00 95.44 ? 137 GLY L CA 1 +ATOM 22000 C C . GLY L 1 137 ? 55.479 63.014 62.386 1.00 105.81 ? 137 GLY L C 1 +ATOM 22001 O O . GLY L 1 137 ? 55.885 62.574 61.317 1.00 85.10 ? 137 GLY L O 1 +ATOM 22002 N N . GLY L 1 138 ? 55.510 64.313 62.683 1.00 145.98 ? 138 GLY L N 1 +ATOM 22003 C CA . GLY L 1 138 ? 56.065 65.307 61.757 1.00 160.09 ? 138 GLY L CA 1 +ATOM 22004 C C . GLY L 1 138 ? 56.333 66.664 62.398 1.00 138.29 ? 138 GLY L C 1 +ATOM 22005 O O . GLY L 1 138 ? 55.582 67.100 63.271 1.00 82.34 ? 138 GLY L O 1 +ATOM 22006 N N . VAL L 1 139 ? 57.393 67.328 61.933 1.00 118.96 ? 139 VAL L N 1 +ATOM 22007 C CA . VAL L 1 139 ? 57.726 68.669 62.379 1.00 110.34 ? 139 VAL L CA 1 +ATOM 22008 C C . VAL L 1 139 ? 58.205 69.514 61.204 1.00 115.43 ? 139 VAL L C 1 +ATOM 22009 O O . VAL L 1 139 ? 59.133 69.135 60.482 1.00 105.42 ? 139 VAL L O 1 +ATOM 22010 C CB . VAL L 1 139 ? 58.835 68.646 63.438 1.00 122.34 ? 139 VAL L CB 1 +ATOM 22011 C CG1 . VAL L 1 139 ? 59.255 70.065 63.792 1.00 118.02 ? 139 VAL L CG1 1 +ATOM 22012 C CG2 . VAL L 1 139 ? 58.382 67.893 64.687 1.00 129.81 ? 139 VAL L CG2 1 +ATOM 22013 N N . GLY L 1 140 ? 57.598 70.688 61.038 1.00 126.74 ? 140 GLY L N 1 +ATOM 22014 C CA . GLY L 1 140 ? 57.969 71.605 59.952 1.00 135.27 ? 140 GLY L CA 1 +ATOM 22015 C C . GLY L 1 140 ? 57.794 73.074 60.278 1.00 128.77 ? 140 GLY L C 1 +ATOM 22016 O O . GLY L 1 140 ? 56.873 73.449 61.004 1.00 122.46 ? 140 GLY L O 1 +ATOM 22017 N N . ALA L 1 141 ? 58.653 73.912 59.700 1.00 126.87 ? 141 ALA L N 1 +ATOM 22018 C CA . ALA L 1 141 ? 58.501 75.357 59.818 1.00 129.08 ? 141 ALA L CA 1 +ATOM 22019 C C . ALA L 1 141 ? 58.875 76.089 58.526 1.00 130.73 ? 141 ALA L C 1 +ATOM 22020 O O . ALA L 1 141 ? 59.826 75.726 57.837 1.00 115.42 ? 141 ALA L O 1 +ATOM 22021 C CB . ALA L 1 141 ? 59.320 75.875 60.988 1.00 117.95 ? 141 ALA L CB 1 +ATOM 22022 N N . ARG L 1 142 ? 58.098 77.111 58.195 1.00 134.41 ? 142 ARG L N 1 +ATOM 22023 C CA . ARG L 1 142 ? 58.472 78.017 57.135 1.00 158.94 ? 142 ARG L CA 1 +ATOM 22024 C C . ARG L 1 142 ? 58.421 79.446 57.656 1.00 210.27 ? 142 ARG L C 1 +ATOM 22025 O O . ARG L 1 142 ? 57.585 79.781 58.499 1.00 202.86 ? 142 ARG L O 1 +ATOM 22026 C CB . ARG L 1 142 ? 57.565 77.854 55.917 1.00 152.25 ? 142 ARG L CB 1 +ATOM 22027 C CG . ARG L 1 142 ? 57.987 78.725 54.735 1.00 167.71 ? 142 ARG L CG 1 +ATOM 22028 C CD . ARG L 1 142 ? 57.905 77.997 53.401 1.00 178.90 ? 142 ARG L CD 1 +ATOM 22029 N NE . ARG L 1 142 ? 56.572 78.052 52.807 1.00 178.75 ? 142 ARG L NE 1 +ATOM 22030 C CZ . ARG L 1 142 ? 56.087 77.173 51.931 1.00 165.65 ? 142 ARG L CZ 1 +ATOM 22031 N NH1 . ARG L 1 142 ? 56.810 76.126 51.559 1.00 178.68 ? 142 ARG L NH1 1 +ATOM 22032 N NH2 . ARG L 1 142 ? 54.861 77.330 51.444 1.00 137.58 ? 142 ARG L NH2 1 +ATOM 22033 N N . TYR L 1 143 ? 59.360 80.265 57.186 1.00 244.25 ? 143 TYR L N 1 +ATOM 22034 C CA . TYR L 1 143 ? 59.556 81.613 57.716 1.00 220.08 ? 143 TYR L CA 1 +ATOM 22035 C C . TYR L 1 143 ? 59.642 82.646 56.590 1.00 180.00 ? 143 TYR L C 1 +ATOM 22036 O O . TYR L 1 143 ? 60.729 83.018 56.133 1.00 143.49 ? 143 TYR L O 1 +ATOM 22037 C CB . TYR L 1 143 ? 60.823 81.647 58.566 1.00 230.00 ? 143 TYR L CB 1 +ATOM 22038 C CG . TYR L 1 143 ? 61.040 82.934 59.291 1.00 224.19 ? 143 TYR L CG 1 +ATOM 22039 C CD1 . TYR L 1 143 ? 60.256 83.272 60.388 1.00 200.00 ? 143 TYR L CD1 1 +ATOM 22040 C CD2 . TYR L 1 143 ? 62.065 83.791 58.916 1.00 215.14 ? 143 TYR L CD2 1 +ATOM 22041 C CE1 . TYR L 1 143 ? 60.476 84.439 61.087 1.00 191.81 ? 143 TYR L CE1 1 +ATOM 22042 C CE2 . TYR L 1 143 ? 62.301 84.959 59.615 1.00 211.96 ? 143 TYR L CE2 1 +ATOM 22043 C CZ . TYR L 1 143 ? 61.500 85.279 60.694 1.00 206.15 ? 143 TYR L CZ 1 +ATOM 22044 O OH . TYR L 1 143 ? 61.720 86.448 61.380 1.00 238.75 ? 143 TYR L OH 1 +ATOM 22045 N N . GLY L 1 145 ? 60.039 82.926 53.930 1.00 199.40 ? 145 GLY L N 1 +ATOM 22046 C CA . GLY L 1 145 ? 60.445 82.495 52.598 1.00 189.60 ? 145 GLY L CA 1 +ATOM 22047 C C . GLY L 1 145 ? 61.160 81.155 52.594 1.00 196.01 ? 145 GLY L C 1 +ATOM 22048 O O . GLY L 1 145 ? 61.161 80.469 51.567 1.00 228.78 ? 145 GLY L O 1 +ATOM 22049 N N . ILE L 1 146 ? 61.728 80.764 53.737 1.00 183.13 ? 146 ILE L N 1 +ATOM 22050 C CA . ILE L 1 146 ? 62.578 79.569 53.828 1.00 178.98 ? 146 ILE L CA 1 +ATOM 22051 C C . ILE L 1 146 ? 61.910 78.529 54.735 1.00 162.03 ? 146 ILE L C 1 +ATOM 22052 O O . ILE L 1 146 ? 61.342 78.878 55.765 1.00 128.87 ? 146 ILE L O 1 +ATOM 22053 C CB . ILE L 1 146 ? 63.978 79.908 54.396 1.00 184.24 ? 146 ILE L CB 1 +ATOM 22054 C CG1 . ILE L 1 146 ? 64.480 81.247 53.838 1.00 163.27 ? 146 ILE L CG1 1 +ATOM 22055 C CG2 . ILE L 1 146 ? 64.974 78.799 54.079 1.00 178.33 ? 146 ILE L CG2 1 +ATOM 22056 C CD1 . ILE L 1 146 ? 64.223 82.428 54.752 1.00 157.87 ? 146 ILE L CD1 1 +ATOM 22057 N N . GLY L 1 147 ? 61.950 77.255 54.351 1.00 149.65 ? 147 GLY L N 1 +ATOM 22058 C CA . GLY L 1 147 ? 61.238 76.228 55.121 1.00 140.30 ? 147 GLY L CA 1 +ATOM 22059 C C . GLY L 1 147 ? 61.840 74.841 55.083 1.00 125.01 ? 147 GLY L C 1 +ATOM 22060 O O . GLY L 1 147 ? 62.507 74.465 54.121 1.00 102.92 ? 147 GLY L O 1 +ATOM 22061 N N . ALA L 1 148 ? 61.545 74.064 56.114 1.00 132.67 ? 148 ALA L N 1 +ATOM 22062 C CA . ALA L 1 148 ? 61.881 72.655 56.116 1.00 147.68 ? 148 ALA L CA 1 +ATOM 22063 C C . ALA L 1 148 ? 60.853 71.859 56.914 1.00 156.53 ? 148 ALA L C 1 +ATOM 22064 O O . ALA L 1 148 ? 60.020 72.417 57.636 1.00 142.78 ? 148 ALA L O 1 +ATOM 22065 C CB . ALA L 1 148 ? 63.275 72.446 56.683 1.00 144.86 ? 148 ALA L CB 1 +ATOM 22066 N N . ASP L 1 149 ? 60.907 70.542 56.767 1.00 156.30 ? 149 ASP L N 1 +ATOM 22067 C CA . ASP L 1 149 ? 60.032 69.659 57.529 1.00 155.57 ? 149 ASP L CA 1 +ATOM 22068 C C . ASP L 1 149 ? 60.537 68.222 57.467 1.00 140.62 ? 149 ASP L C 1 +ATOM 22069 O O . ASP L 1 149 ? 61.102 67.807 56.448 1.00 119.65 ? 149 ASP L O 1 +ATOM 22070 C CB . ASP L 1 149 ? 58.575 69.771 57.032 1.00 152.48 ? 149 ASP L CB 1 +ATOM 22071 C CG . ASP L 1 149 ? 58.316 68.973 55.787 1.00 151.84 ? 149 ASP L CG 1 +ATOM 22072 O OD1 . ASP L 1 149 ? 58.764 69.406 54.708 1.00 165.18 ? 149 ASP L OD1 1 +ATOM 22073 O OD2 . ASP L 1 149 ? 57.682 67.907 55.894 1.00 133.95 ? 149 ASP L OD2 1 +ATOM 22074 N N . THR L 1 150 ? 60.322 67.469 58.543 1.00 117.67 ? 150 THR L N 1 +ATOM 22075 C CA . THR L 1 150 ? 60.440 66.026 58.459 1.00 127.72 ? 150 THR L CA 1 +ATOM 22076 C C . THR L 1 150 ? 59.142 65.350 58.881 1.00 149.57 ? 150 THR L C 1 +ATOM 22077 O O . THR L 1 150 ? 58.311 65.927 59.585 1.00 124.71 ? 150 THR L O 1 +ATOM 22078 C CB . THR L 1 150 ? 61.569 65.484 59.334 1.00 125.86 ? 150 THR L CB 1 +ATOM 22079 O OG1 . THR L 1 150 ? 61.324 65.843 60.696 1.00 145.09 ? 150 THR L OG1 1 +ATOM 22080 C CG2 . THR L 1 150 ? 62.906 66.031 58.881 1.00 122.50 ? 150 THR L CG2 1 +ATOM 22081 N N . GLN L 1 151 ? 58.948 64.138 58.372 1.00 169.33 ? 151 GLN L N 1 +ATOM 22082 C CA . GLN L 1 151 ? 57.819 63.303 58.742 1.00 150.38 ? 151 GLN L CA 1 +ATOM 22083 C C . GLN L 1 151 ? 58.310 61.881 58.911 1.00 134.60 ? 151 GLN L C 1 +ATOM 22084 O O . GLN L 1 151 ? 59.181 61.459 58.173 1.00 116.35 ? 151 GLN L O 1 +ATOM 22085 C CB . GLN L 1 151 ? 56.754 63.375 57.648 1.00 149.26 ? 151 GLN L CB 1 +ATOM 22086 C CG . GLN L 1 151 ? 56.017 64.698 57.626 1.00 148.52 ? 151 GLN L CG 1 +ATOM 22087 C CD . GLN L 1 151 ? 55.367 64.963 56.292 1.00 165.77 ? 151 GLN L CD 1 +ATOM 22088 O OE1 . GLN L 1 151 ? 54.815 64.051 55.678 1.00 131.94 ? 151 GLN L OE1 1 +ATOM 22089 N NE2 . GLN L 1 151 ? 55.440 66.211 55.824 1.00 189.46 ? 151 GLN L NE2 1 +ATOM 22090 N N . TYR L 1 152 ? 57.767 61.145 59.877 1.00 110.27 ? 152 TYR L N 1 +ATOM 22091 C CA . TYR L 1 152 ? 58.157 59.756 60.046 1.00 100.97 ? 152 TYR L CA 1 +ATOM 22092 C C . TYR L 1 152 ? 56.985 58.844 60.319 1.00 110.17 ? 152 TYR L C 1 +ATOM 22093 O O . TYR L 1 152 ? 55.982 59.260 60.901 1.00 112.54 ? 152 TYR L O 1 +ATOM 22094 C CB . TYR L 1 152 ? 59.179 59.641 61.149 1.00 95.59 ? 152 TYR L CB 1 +ATOM 22095 C CG . TYR L 1 152 ? 58.672 59.074 62.457 1.00 91.23 ? 152 TYR L CG 1 +ATOM 22096 C CD1 . TYR L 1 152 ? 57.730 59.751 63.239 1.00 77.58 ? 152 TYR L CD1 1 +ATOM 22097 C CD2 . TYR L 1 152 ? 59.257 57.941 62.986 1.00 89.07 ? 152 TYR L CD2 1 +ATOM 22098 C CE1 . TYR L 1 152 ? 57.314 59.251 64.460 1.00 73.20 ? 152 TYR L CE1 1 +ATOM 22099 C CE2 . TYR L 1 152 ? 58.906 57.478 64.239 1.00 90.13 ? 152 TYR L CE2 1 +ATOM 22100 C CZ . TYR L 1 152 ? 57.921 58.125 64.962 1.00 84.43 ? 152 TYR L CZ 1 +ATOM 22101 O OH . TYR L 1 152 ? 57.575 57.638 66.208 1.00 124.89 ? 152 TYR L OH 1 +ATOM 22102 N N . GLN L 1 153 ? 57.091 57.608 59.841 1.00 127.22 ? 153 GLN L N 1 +ATOM 22103 C CA . GLN L 1 153 ? 56.130 56.574 60.190 1.00 133.46 ? 153 GLN L CA 1 +ATOM 22104 C C . GLN L 1 153 ? 56.862 55.283 60.529 1.00 120.30 ? 153 GLN L C 1 +ATOM 22105 O O . GLN L 1 153 ? 57.976 55.053 60.050 1.00 141.72 ? 153 GLN L O 1 +ATOM 22106 C CB . GLN L 1 153 ? 55.148 56.350 59.034 1.00 144.12 ? 153 GLN L CB 1 +ATOM 22107 C CG . GLN L 1 153 ? 54.234 57.542 58.716 1.00 143.87 ? 153 GLN L CG 1 +ATOM 22108 C CD . GLN L 1 153 ? 53.381 57.284 57.465 1.00 161.95 ? 153 GLN L CD 1 +ATOM 22109 O OE1 . GLN L 1 153 ? 53.691 56.401 56.649 1.00 167.72 ? 153 GLN L OE1 1 +ATOM 22110 N NE2 . GLN L 1 153 ? 52.277 58.011 57.337 1.00 171.72 ? 153 GLN L NE2 1 +ATOM 22111 N N . LEU L 1 154 ? 56.249 54.449 61.362 1.00 98.88 ? 154 LEU L N 1 +ATOM 22112 C CA . LEU L 1 154 ? 56.811 53.129 61.606 1.00 103.68 ? 154 LEU L CA 1 +ATOM 22113 C C . LEU L 1 154 ? 55.757 52.036 61.770 1.00 118.87 ? 154 LEU L C 1 +ATOM 22114 O O . LEU L 1 154 ? 54.678 52.251 62.352 1.00 115.15 ? 154 LEU L O 1 +ATOM 22115 C CB . LEU L 1 154 ? 57.744 53.155 62.811 1.00 83.14 ? 154 LEU L CB 1 +ATOM 22116 C CG . LEU L 1 154 ? 57.054 53.308 64.159 1.00 92.86 ? 154 LEU L CG 1 +ATOM 22117 C CD1 . LEU L 1 154 ? 56.825 51.969 64.827 1.00 87.30 ? 154 LEU L CD1 1 +ATOM 22118 C CD2 . LEU L 1 154 ? 57.887 54.214 65.049 1.00 135.60 ? 154 LEU L CD2 1 +ATOM 22119 N N . ASP L 1 155 ? 56.146 50.837 61.328 1.00 124.73 ? 155 ASP L N 1 +ATOM 22120 C CA . ASP L 1 155 ? 55.266 49.668 61.200 1.00 98.18 ? 155 ASP L CA 1 +ATOM 22121 C C . ASP L 1 155 ? 55.829 48.534 62.056 1.00 88.89 ? 155 ASP L C 1 +ATOM 22122 O O . ASP L 1 155 ? 57.004 48.544 62.409 1.00 94.36 ? 155 ASP L O 1 +ATOM 22123 C CB . ASP L 1 155 ? 55.200 49.228 59.735 1.00 93.99 ? 155 ASP L CB 1 +ATOM 22124 C CG . ASP L 1 155 ? 54.971 50.396 58.789 1.00 113.82 ? 155 ASP L CG 1 +ATOM 22125 O OD1 . ASP L 1 155 ? 55.952 51.118 58.475 1.00 142.86 ? 155 ASP L OD1 1 +ATOM 22126 O OD2 . ASP L 1 155 ? 53.823 50.581 58.341 1.00 123.24 ? 155 ASP L OD2 1 +ATOM 22127 N N . GLN L 1 156 ? 55.000 47.550 62.379 1.00 78.34 ? 156 GLN L N 1 +ATOM 22128 C CA . GLN L 1 156 ? 55.462 46.398 63.158 1.00 76.78 ? 156 GLN L CA 1 +ATOM 22129 C C . GLN L 1 156 ? 55.451 45.095 62.320 1.00 70.09 ? 156 GLN L C 1 +ATOM 22130 O O . GLN L 1 156 ? 54.647 44.943 61.405 1.00 74.09 ? 156 GLN L O 1 +ATOM 22131 C CB . GLN L 1 156 ? 54.612 46.279 64.428 1.00 79.09 ? 156 GLN L CB 1 +ATOM 22132 C CG . GLN L 1 156 ? 55.169 45.326 65.470 1.00 97.37 ? 156 GLN L CG 1 +ATOM 22133 C CD . GLN L 1 156 ? 54.672 45.631 66.883 1.00 103.77 ? 156 GLN L CD 1 +ATOM 22134 O OE1 . GLN L 1 156 ? 53.753 46.426 67.065 1.00 122.32 ? 156 GLN L OE1 1 +ATOM 22135 N NE2 . GLN L 1 156 ? 55.217 44.922 67.871 1.00 78.50 ? 156 GLN L NE2 1 +ATOM 22136 N N . ILE L 1 157 ? 56.303 44.150 62.682 1.00 56.23 ? 157 ILE L N 1 +ATOM 22137 C CA . ILE L 1 157 ? 56.252 42.811 62.121 1.00 49.78 ? 157 ILE L CA 1 +ATOM 22138 C C . ILE L 1 157 ? 56.697 41.769 63.187 1.00 54.35 ? 157 ILE L C 1 +ATOM 22139 O O . ILE L 1 157 ? 57.528 42.058 64.044 1.00 58.17 ? 157 ILE L O 1 +ATOM 22140 C CB . ILE L 1 157 ? 57.170 42.757 60.920 1.00 48.81 ? 157 ILE L CB 1 +ATOM 22141 C CG1 . ILE L 1 157 ? 56.746 41.633 59.986 1.00 91.09 ? 157 ILE L CG1 1 +ATOM 22142 C CG2 . ILE L 1 157 ? 58.594 42.544 61.354 1.00 47.64 ? 157 ILE L CG2 1 +ATOM 22143 C CD1 . ILE L 1 157 ? 57.484 41.616 58.661 1.00 109.64 ? 157 ILE L CD1 1 +ATOM 22144 N N . ALA L 1 158 ? 56.012 40.634 63.260 1.00 53.26 ? 158 ALA L N 1 +ATOM 22145 C CA . ALA L 1 158 ? 56.320 39.677 64.304 1.00 44.09 ? 158 ALA L CA 1 +ATOM 22146 C C . ALA L 1 158 ? 56.386 38.307 63.697 1.00 36.34 ? 158 ALA L C 1 +ATOM 22147 O O . ALA L 1 158 ? 55.746 37.998 62.689 1.00 23.82 ? 158 ALA L O 1 +ATOM 22148 C CB . ALA L 1 158 ? 55.282 39.716 65.425 1.00 54.49 ? 158 ALA L CB 1 +ATOM 22149 N N . VAL L 1 159 ? 57.170 37.475 64.332 1.00 35.53 ? 159 VAL L N 1 +ATOM 22150 C CA . VAL L 1 159 ? 57.440 36.154 63.804 1.00 41.08 ? 159 VAL L CA 1 +ATOM 22151 C C . VAL L 1 159 ? 57.438 35.135 64.948 1.00 45.14 ? 159 VAL L C 1 +ATOM 22152 O O . VAL L 1 159 ? 58.117 35.309 65.966 1.00 55.79 ? 159 VAL L O 1 +ATOM 22153 C CB . VAL L 1 159 ? 58.802 36.134 63.053 1.00 42.15 ? 159 VAL L CB 1 +ATOM 22154 C CG1 . VAL L 1 159 ? 59.352 34.728 62.939 1.00 47.53 ? 159 VAL L CG1 1 +ATOM 22155 C CG2 . VAL L 1 159 ? 58.670 36.736 61.692 1.00 36.78 ? 159 VAL L CG2 1 +ATOM 22156 N N . ASN L 1 160 ? 56.682 34.081 64.764 1.00 46.17 ? 160 ASN L N 1 +ATOM 22157 C CA . ASN L 1 160 ? 56.784 32.934 65.608 1.00 63.79 ? 160 ASN L CA 1 +ATOM 22158 C C . ASN L 1 160 ? 57.753 31.923 64.945 1.00 63.62 ? 160 ASN L C 1 +ATOM 22159 O O . ASN L 1 160 ? 57.604 31.579 63.772 1.00 64.15 ? 160 ASN L O 1 +ATOM 22160 C CB . ASN L 1 160 ? 55.384 32.322 65.783 1.00 83.53 ? 160 ASN L CB 1 +ATOM 22161 C CG . ASN L 1 160 ? 55.382 31.047 66.655 1.00 107.49 ? 160 ASN L CG 1 +ATOM 22162 O OD1 . ASN L 1 160 ? 56.117 30.097 66.386 1.00 84.27 ? 160 ASN L OD1 1 +ATOM 22163 N ND2 . ASN L 1 160 ? 54.420 30.958 67.564 1.00 122.39 ? 160 ASN L ND2 1 +ATOM 22164 N N . LEU L 1 161 ? 58.693 31.404 65.722 1.00 51.71 ? 161 LEU L N 1 +ATOM 22165 C CA . LEU L 1 161 ? 59.344 30.154 65.391 1.00 40.28 ? 161 LEU L CA 1 +ATOM 22166 C C . LEU L 1 161 ? 59.149 29.170 66.518 1.00 42.29 ? 161 LEU L C 1 +ATOM 22167 O O . LEU L 1 161 ? 59.137 29.527 67.703 1.00 72.67 ? 161 LEU L O 1 +ATOM 22168 C CB . LEU L 1 161 ? 60.809 30.415 65.170 1.00 44.90 ? 161 LEU L CB 1 +ATOM 22169 C CG . LEU L 1 161 ? 61.132 31.316 63.985 1.00 53.26 ? 161 LEU L CG 1 +ATOM 22170 C CD1 . LEU L 1 161 ? 62.619 31.665 63.994 1.00 73.01 ? 161 LEU L CD1 1 +ATOM 22171 C CD2 . LEU L 1 161 ? 60.745 30.611 62.691 1.00 52.09 ? 161 LEU L CD2 1 +ATOM 22172 N N . ARG L 1 162 ? 59.143 27.903 66.205 1.00 47.21 ? 162 ARG L N 1 +ATOM 22173 C CA . ARG L 1 162 ? 59.000 26.911 67.253 1.00 61.26 ? 162 ARG L CA 1 +ATOM 22174 C C . ARG L 1 162 ? 59.604 25.562 66.908 1.00 63.19 ? 162 ARG L C 1 +ATOM 22175 O O . ARG L 1 162 ? 59.342 24.987 65.826 1.00 114.04 ? 162 ARG L O 1 +ATOM 22176 C CB . ARG L 1 162 ? 57.526 26.788 67.679 1.00 69.00 ? 162 ARG L CB 1 +ATOM 22177 C CG . ARG L 1 162 ? 56.530 26.309 66.631 1.00 84.60 ? 162 ARG L CG 1 +ATOM 22178 C CD . ARG L 1 162 ? 55.237 25.852 67.325 1.00 101.85 ? 162 ARG L CD 1 +ATOM 22179 N NE . ARG L 1 162 ? 54.213 25.182 66.525 1.00 90.05 ? 162 ARG L NE 1 +ATOM 22180 C CZ . ARG L 1 162 ? 53.312 25.849 65.803 1.00 90.46 ? 162 ARG L CZ 1 +ATOM 22181 N NH1 . ARG L 1 162 ? 53.443 27.168 65.543 1.00 87.88 ? 162 ARG L NH1 1 +ATOM 22182 N NH2 . ARG L 1 162 ? 52.336 25.173 65.253 1.00 95.77 ? 162 ARG L NH2 1 +ATOM 22183 N N . VAL L 1 163 ? 60.399 25.046 67.839 1.00 52.01 ? 163 VAL L N 1 +ATOM 22184 C CA . VAL L 1 163 ? 60.969 23.694 67.713 1.00 61.16 ? 163 VAL L CA 1 +ATOM 22185 C C . VAL L 1 163 ? 60.012 22.583 68.148 1.00 47.10 ? 163 VAL L C 1 +ATOM 22186 O O . VAL L 1 163 ? 59.565 22.568 69.287 1.00 68.86 ? 163 VAL L O 1 +ATOM 22187 C CB . VAL L 1 163 ? 62.211 23.531 68.602 1.00 72.58 ? 163 VAL L CB 1 +ATOM 22188 C CG1 . VAL L 1 163 ? 62.798 22.108 68.438 1.00 68.66 ? 163 VAL L CG1 1 +ATOM 22189 C CG2 . VAL L 1 163 ? 63.218 24.640 68.319 1.00 74.39 ? 163 VAL L CG2 1 +ATOM 22190 N N . VAL L 1 164 ? 59.801 21.623 67.269 1.00 40.74 ? 164 VAL L N 1 +ATOM 22191 C CA . VAL L 1 164 ? 58.910 20.497 67.513 1.00 37.09 ? 164 VAL L CA 1 +ATOM 22192 C C . VAL L 1 164 ? 59.731 19.280 67.510 1.00 36.33 ? 164 VAL L C 1 +ATOM 22193 O O . VAL L 1 164 ? 60.524 19.066 66.598 1.00 40.32 ? 164 VAL L O 1 +ATOM 22194 C CB . VAL L 1 164 ? 57.833 20.347 66.398 1.00 34.33 ? 164 VAL L CB 1 +ATOM 22195 C CG1 . VAL L 1 164 ? 56.969 19.159 66.656 1.00 25.16 ? 164 VAL L CG1 1 +ATOM 22196 C CG2 . VAL L 1 164 ? 56.968 21.623 66.352 1.00 47.14 ? 164 VAL L CG2 1 +ATOM 22197 N N . ASN L 1 165 ? 59.479 18.448 68.489 1.00 56.66 ? 165 ASN L N 1 +ATOM 22198 C CA . ASN L 1 165 ? 60.142 17.155 68.572 1.00 87.95 ? 165 ASN L CA 1 +ATOM 22199 C C . ASN L 1 165 ? 59.446 16.084 67.721 1.00 86.00 ? 165 ASN L C 1 +ATOM 22200 O O . ASN L 1 165 ? 58.291 15.750 67.961 1.00 61.54 ? 165 ASN L O 1 +ATOM 22201 C CB . ASN L 1 165 ? 60.220 16.665 70.015 1.00 88.64 ? 165 ASN L CB 1 +ATOM 22202 C CG . ASN L 1 165 ? 61.160 15.494 70.169 1.00 100.57 ? 165 ASN L CG 1 +ATOM 22203 O OD1 . ASN L 1 165 ? 61.851 15.109 69.219 1.00 131.55 ? 165 ASN L OD1 1 +ATOM 22204 N ND2 . ASN L 1 165 ? 61.082 14.832 71.298 1.00 124.06 ? 165 ASN L ND2 1 +ATOM 22205 N N . VAL L 1 166 ? 60.170 15.575 66.719 1.00 94.22 ? 166 VAL L N 1 +ATOM 22206 C CA . VAL L 1 166 ? 59.634 14.615 65.760 1.00 84.48 ? 166 VAL L CA 1 +ATOM 22207 C C . VAL L 1 166 ? 59.186 13.386 66.482 1.00 66.28 ? 166 VAL L C 1 +ATOM 22208 O O . VAL L 1 166 ? 58.158 12.829 66.167 1.00 83.80 ? 166 VAL L O 1 +ATOM 22209 C CB . VAL L 1 166 ? 60.695 14.240 64.705 1.00 101.28 ? 166 VAL L CB 1 +ATOM 22210 C CG1 . VAL L 1 166 ? 60.433 12.863 64.115 1.00 96.83 ? 166 VAL L CG1 1 +ATOM 22211 C CG2 . VAL L 1 166 ? 60.772 15.321 63.622 1.00 104.03 ? 166 VAL L CG2 1 +ATOM 22212 N N . SER L 1 167 ? 59.945 12.994 67.485 1.00 65.61 ? 167 SER L N 1 +ATOM 22213 C CA . SER L 1 167 ? 59.706 11.741 68.158 1.00 82.33 ? 167 SER L CA 1 +ATOM 22214 C C . SER L 1 167 ? 58.427 11.752 69.008 1.00 80.12 ? 167 SER L C 1 +ATOM 22215 O O . SER L 1 167 ? 57.994 10.680 69.466 1.00 89.34 ? 167 SER L O 1 +ATOM 22216 C CB . SER L 1 167 ? 60.932 11.376 69.008 1.00 97.28 ? 167 SER L CB 1 +ATOM 22217 O OG . SER L 1 167 ? 62.131 11.579 68.266 1.00 139.93 ? 167 SER L OG 1 +ATOM 22218 N N . THR L 1 168 ? 57.870 12.941 69.282 1.00 64.05 ? 168 THR L N 1 +ATOM 22219 C CA . THR L 1 168 ? 56.714 13.034 70.184 1.00 65.30 ? 168 THR L CA 1 +ATOM 22220 C C . THR L 1 168 ? 55.638 13.978 69.725 1.00 70.34 ? 168 THR L C 1 +ATOM 22221 O O . THR L 1 168 ? 54.422 13.774 69.937 1.00 62.48 ? 168 THR L O 1 +ATOM 22222 C CB . THR L 1 168 ? 57.116 13.488 71.597 1.00 69.24 ? 168 THR L CB 1 +ATOM 22223 O OG1 . THR L 1 168 ? 57.924 14.657 71.509 1.00 47.11 ? 168 THR L OG1 1 +ATOM 22224 C CG2 . THR L 1 168 ? 57.894 12.372 72.323 1.00 101.29 ? 168 THR L CG2 1 +ATOM 22225 N N . GLY L 1 169 ? 56.072 15.069 69.143 1.00 77.29 ? 169 GLY L N 1 +ATOM 22226 C CA . GLY L 1 169 ? 55.106 16.091 68.766 1.00 95.98 ? 169 GLY L CA 1 +ATOM 22227 C C . GLY L 1 169 ? 55.092 17.200 69.793 1.00 61.50 ? 169 GLY L C 1 +ATOM 22228 O O . GLY L 1 169 ? 54.457 18.214 69.576 1.00 50.29 ? 169 GLY L O 1 +ATOM 22229 N N . GLU L 1 170 ? 55.732 16.957 70.929 1.00 51.55 ? 170 GLU L N 1 +ATOM 22230 C CA . GLU L 1 170 ? 55.898 17.990 71.937 1.00 51.36 ? 170 GLU L CA 1 +ATOM 22231 C C . GLU L 1 170 ? 56.570 19.101 71.227 1.00 43.14 ? 170 GLU L C 1 +ATOM 22232 O O . GLU L 1 170 ? 57.587 18.927 70.570 1.00 49.04 ? 170 GLU L O 1 +ATOM 22233 C CB . GLU L 1 170 ? 56.765 17.516 73.120 1.00 70.49 ? 170 GLU L CB 1 +ATOM 22234 C CG . GLU L 1 170 ? 56.030 16.638 74.134 1.00 99.80 ? 170 GLU L CG 1 +ATOM 22235 C CD . GLU L 1 170 ? 56.872 15.500 74.727 1.00 133.95 ? 170 GLU L CD 1 +ATOM 22236 O OE1 . GLU L 1 170 ? 57.965 15.218 74.203 1.00 144.81 ? 170 GLU L OE1 1 +ATOM 22237 O OE2 . GLU L 1 170 ? 56.392 14.814 75.659 1.00 148.70 ? 170 GLU L OE2 1 +ATOM 22238 N N . ILE L 1 171 ? 56.022 20.283 71.368 1.00 52.99 ? 171 ILE L N 1 +ATOM 22239 C CA . ILE L 1 171 ? 56.774 21.475 71.035 1.00 57.73 ? 171 ILE L CA 1 +ATOM 22240 C C . ILE L 1 171 ? 57.846 21.700 72.098 1.00 59.75 ? 171 ILE L C 1 +ATOM 22241 O O . ILE L 1 171 ? 57.549 21.711 73.284 1.00 82.39 ? 171 ILE L O 1 +ATOM 22242 C CB . ILE L 1 171 ? 55.854 22.699 70.942 1.00 53.38 ? 171 ILE L CB 1 +ATOM 22243 C CG1 . ILE L 1 171 ? 54.944 22.565 69.705 1.00 43.17 ? 171 ILE L CG1 1 +ATOM 22244 C CG2 . ILE L 1 171 ? 56.706 23.971 70.908 1.00 47.11 ? 171 ILE L CG2 1 +ATOM 22245 C CD1 . ILE L 1 171 ? 53.780 23.491 69.751 1.00 37.56 ? 171 ILE L CD1 1 +ATOM 22246 N N . LEU L 1 172 ? 59.106 21.785 71.682 1.00 61.88 ? 172 LEU L N 1 +ATOM 22247 C CA . LEU L 1 172 ? 60.207 21.893 72.643 1.00 58.16 ? 172 LEU L CA 1 +ATOM 22248 C C . LEU L 1 172 ? 60.533 23.354 72.977 1.00 54.05 ? 172 LEU L C 1 +ATOM 22249 O O . LEU L 1 172 ? 61.320 23.651 73.884 1.00 56.74 ? 172 LEU L O 1 +ATOM 22250 C CB . LEU L 1 172 ? 61.447 21.130 72.153 1.00 63.47 ? 172 LEU L CB 1 +ATOM 22251 C CG . LEU L 1 172 ? 61.307 19.584 72.152 1.00 80.57 ? 172 LEU L CG 1 +ATOM 22252 C CD1 . LEU L 1 172 ? 62.557 18.748 71.817 1.00 79.32 ? 172 LEU L CD1 1 +ATOM 22253 C CD2 . LEU L 1 172 ? 60.652 19.075 73.425 1.00 108.17 ? 172 LEU L CD2 1 +ATOM 22254 N N . SER L 1 173 ? 59.995 24.259 72.170 1.00 60.94 ? 173 SER L N 1 +ATOM 22255 C CA . SER L 1 173 ? 60.295 25.672 72.295 1.00 66.04 ? 173 SER L CA 1 +ATOM 22256 C C . SER L 1 173 ? 59.433 26.498 71.355 1.00 60.37 ? 173 SER L C 1 +ATOM 22257 O O . SER L 1 173 ? 59.396 26.257 70.155 1.00 57.96 ? 173 SER L O 1 +ATOM 22258 C CB . SER L 1 173 ? 61.779 25.975 71.986 1.00 81.82 ? 173 SER L CB 1 +ATOM 22259 O OG . SER L 1 173 ? 61.979 27.377 71.830 1.00 105.90 ? 173 SER L OG 1 +ATOM 22260 N N . SER L 1 174 ? 58.805 27.530 71.897 1.00 70.42 ? 174 SER L N 1 +ATOM 22261 C CA . SER L 1 174 ? 58.152 28.558 71.083 1.00 80.08 ? 174 SER L CA 1 +ATOM 22262 C C . SER L 1 174 ? 58.724 29.923 71.430 1.00 76.47 ? 174 SER L C 1 +ATOM 22263 O O . SER L 1 174 ? 58.932 30.230 72.589 1.00 70.56 ? 174 SER L O 1 +ATOM 22264 C CB . SER L 1 174 ? 56.628 28.570 71.307 1.00 88.76 ? 174 SER L CB 1 +ATOM 22265 O OG . SER L 1 174 ? 55.940 29.373 70.350 1.00 62.70 ? 174 SER L OG 1 +ATOM 22266 N N . VAL L 1 175 ? 58.976 30.733 70.401 1.00 87.76 ? 175 VAL L N 1 +ATOM 22267 C CA . VAL L 1 175 ? 59.518 32.097 70.579 1.00 73.74 ? 175 VAL L CA 1 +ATOM 22268 C C . VAL L 1 175 ? 58.846 33.103 69.661 1.00 55.85 ? 175 VAL L C 1 +ATOM 22269 O O . VAL L 1 175 ? 58.470 32.755 68.517 1.00 73.30 ? 175 VAL L O 1 +ATOM 22270 C CB . VAL L 1 175 ? 61.033 32.127 70.324 1.00 89.11 ? 175 VAL L CB 1 +ATOM 22271 C CG1 . VAL L 1 175 ? 61.776 31.248 71.321 1.00 93.66 ? 175 VAL L CG1 1 +ATOM 22272 C CG2 . VAL L 1 175 ? 61.372 31.653 68.915 1.00 99.12 ? 175 VAL L CG2 1 +ATOM 22273 N N . ASN L 1 176 ? 58.683 34.315 70.154 1.00 49.48 ? 176 ASN L N 1 +ATOM 22274 C CA . ASN L 1 176 ? 57.853 35.330 69.458 1.00 57.80 ? 176 ASN L CA 1 +ATOM 22275 C C . ASN L 1 176 ? 58.559 36.670 69.265 1.00 59.94 ? 176 ASN L C 1 +ATOM 22276 O O . ASN L 1 176 ? 58.574 37.480 70.174 1.00 62.20 ? 176 ASN L O 1 +ATOM 22277 C CB . ASN L 1 176 ? 56.574 35.580 70.265 1.00 61.09 ? 176 ASN L CB 1 +ATOM 22278 C CG . ASN L 1 176 ? 55.353 34.850 69.704 1.00 81.06 ? 176 ASN L CG 1 +ATOM 22279 O OD1 . ASN L 1 176 ? 54.177 35.077 70.142 1.00 125.19 ? 176 ASN L OD1 1 +ATOM 22280 N ND2 . ASN L 1 176 ? 55.615 33.915 68.797 1.00 70.95 ? 176 ASN L ND2 1 +ATOM 22281 N N . THR L 1 177 ? 59.234 36.850 68.134 1.00 63.96 ? 177 THR L N 1 +ATOM 22282 C CA . THR L 1 177 ? 60.094 38.016 67.938 1.00 59.59 ? 177 THR L CA 1 +ATOM 22283 C C . THR L 1 177 ? 59.363 39.057 67.151 1.00 65.40 ? 177 THR L C 1 +ATOM 22284 O O . THR L 1 177 ? 58.360 38.776 66.499 1.00 57.29 ? 177 THR L O 1 +ATOM 22285 C CB . THR L 1 177 ? 61.397 37.681 67.187 1.00 72.16 ? 177 THR L CB 1 +ATOM 22286 O OG1 . THR L 1 177 ? 61.104 37.316 65.835 1.00 55.69 ? 177 THR L OG1 1 +ATOM 22287 C CG2 . THR L 1 177 ? 62.162 36.512 67.860 1.00 81.64 ? 177 THR L CG2 1 +ATOM 22288 N N . SER L 1 178 ? 59.825 40.284 67.293 1.00 82.04 ? 178 SER L N 1 +ATOM 22289 C CA . SER L 1 178 ? 59.134 41.424 66.707 1.00 85.16 ? 178 SER L CA 1 +ATOM 22290 C C . SER L 1 178 ? 60.133 42.468 66.281 1.00 79.51 ? 178 SER L C 1 +ATOM 22291 O O . SER L 1 178 ? 61.232 42.592 66.843 1.00 95.37 ? 178 SER L O 1 +ATOM 22292 C CB . SER L 1 178 ? 58.149 42.048 67.696 1.00 91.63 ? 178 SER L CB 1 +ATOM 22293 O OG . SER L 1 178 ? 57.721 43.335 67.266 1.00 87.08 ? 178 SER L OG 1 +ATOM 22294 N N . LYS L 1 179 ? 59.744 43.250 65.293 1.00 68.59 ? 179 LYS L N 1 +ATOM 22295 C CA . LYS L 1 179 ? 60.672 44.199 64.722 1.00 82.06 ? 179 LYS L CA 1 +ATOM 22296 C C . LYS L 1 179 ? 59.908 45.367 64.094 1.00 86.85 ? 179 LYS L C 1 +ATOM 22297 O O . LYS L 1 179 ? 58.823 45.200 63.532 1.00 64.92 ? 179 LYS L O 1 +ATOM 22298 C CB . LYS L 1 179 ? 61.559 43.485 63.695 1.00 81.52 ? 179 LYS L CB 1 +ATOM 22299 C CG . LYS L 1 179 ? 62.990 43.975 63.637 1.00 87.91 ? 179 LYS L CG 1 +ATOM 22300 C CD . LYS L 1 179 ? 63.136 45.039 62.566 1.00 99.70 ? 179 LYS L CD 1 +ATOM 22301 C CE . LYS L 1 179 ? 64.515 45.655 62.623 1.00 109.38 ? 179 LYS L CE 1 +ATOM 22302 N NZ . LYS L 1 179 ? 64.593 46.883 61.800 1.00 128.23 ? 179 LYS L NZ 1 +ATOM 22303 N N . THR L 1 180 ? 60.505 46.549 64.179 1.00 90.78 ? 180 THR L N 1 +ATOM 22304 C CA . THR L 1 180 ? 59.857 47.750 63.706 1.00 84.59 ? 180 THR L CA 1 +ATOM 22305 C C . THR L 1 180 ? 60.503 48.235 62.403 1.00 84.71 ? 180 THR L C 1 +ATOM 22306 O O . THR L 1 180 ? 61.735 48.333 62.285 1.00 99.87 ? 180 THR L O 1 +ATOM 22307 C CB . THR L 1 180 ? 59.862 48.849 64.781 1.00 81.20 ? 180 THR L CB 1 +ATOM 22308 O OG1 . THR L 1 180 ? 59.767 50.132 64.157 1.00 79.12 ? 180 THR L OG1 1 +ATOM 22309 C CG2 . THR L 1 180 ? 61.138 48.790 65.625 1.00 88.85 ? 180 THR L CG2 1 +ATOM 22310 N N . ILE L 1 181 ? 59.660 48.564 61.436 1.00 82.60 ? 181 ILE L N 1 +ATOM 22311 C CA . ILE L 1 181 ? 60.124 49.102 60.163 1.00 91.86 ? 181 ILE L CA 1 +ATOM 22312 C C . ILE L 1 181 ? 60.002 50.642 60.128 1.00 95.28 ? 181 ILE L C 1 +ATOM 22313 O O . ILE L 1 181 ? 58.892 51.193 60.216 1.00 104.40 ? 181 ILE L O 1 +ATOM 22314 C CB . ILE L 1 181 ? 59.331 48.481 58.988 1.00 113.84 ? 181 ILE L CB 1 +ATOM 22315 C CG1 . ILE L 1 181 ? 59.349 46.957 59.079 1.00 105.37 ? 181 ILE L CG1 1 +ATOM 22316 C CG2 . ILE L 1 181 ? 59.893 48.911 57.635 1.00 135.83 ? 181 ILE L CG2 1 +ATOM 22317 C CD1 . ILE L 1 181 ? 57.976 46.342 59.221 1.00 102.42 ? 181 ILE L CD1 1 +ATOM 22318 N N . LEU L 1 182 ? 61.140 51.321 59.965 1.00 81.78 ? 182 LEU L N 1 +ATOM 22319 C CA . LEU L 1 182 ? 61.201 52.779 59.993 1.00 82.00 ? 182 LEU L CA 1 +ATOM 22320 C C . LEU L 1 182 ? 61.111 53.418 58.619 1.00 94.06 ? 182 LEU L C 1 +ATOM 22321 O O . LEU L 1 182 ? 61.746 52.974 57.658 1.00 78.35 ? 182 LEU L O 1 +ATOM 22322 C CB . LEU L 1 182 ? 62.497 53.232 60.650 1.00 87.54 ? 182 LEU L CB 1 +ATOM 22323 C CG . LEU L 1 182 ? 62.711 54.749 60.730 1.00 90.17 ? 182 LEU L CG 1 +ATOM 22324 C CD1 . LEU L 1 182 ? 61.649 55.465 61.563 1.00 78.91 ? 182 LEU L CD1 1 +ATOM 22325 C CD2 . LEU L 1 182 ? 64.104 55.001 61.291 1.00 105.66 ? 182 LEU L CD2 1 +ATOM 22326 N N . SER L 1 183 ? 60.361 54.517 58.551 1.00 129.78 ? 183 SER L N 1 +ATOM 22327 C CA . SER L 1 183 ? 60.282 55.342 57.345 1.00 142.05 ? 183 SER L CA 1 +ATOM 22328 C C . SER L 1 183 ? 60.318 56.838 57.718 1.00 124.47 ? 183 SER L C 1 +ATOM 22329 O O . SER L 1 183 ? 59.705 57.250 58.698 1.00 96.51 ? 183 SER L O 1 +ATOM 22330 C CB . SER L 1 183 ? 59.000 55.012 56.570 1.00 129.91 ? 183 SER L CB 1 +ATOM 22331 O OG . SER L 1 183 ? 58.713 53.618 56.636 1.00 140.83 ? 183 SER L OG 1 +ATOM 22332 N N . TYR L 1 184 ? 61.027 57.637 56.927 1.00 110.23 ? 184 TYR L N 1 +ATOM 22333 C CA . TYR L 1 184 ? 61.034 59.078 57.132 1.00 102.92 ? 184 TYR L CA 1 +ATOM 22334 C C . TYR L 1 184 ? 61.249 59.890 55.850 1.00 135.90 ? 184 TYR L C 1 +ATOM 22335 O O . TYR L 1 184 ? 61.828 59.421 54.861 1.00 130.89 ? 184 TYR L O 1 +ATOM 22336 C CB . TYR L 1 184 ? 62.062 59.465 58.184 1.00 93.38 ? 184 TYR L CB 1 +ATOM 22337 C CG . TYR L 1 184 ? 63.469 59.043 57.846 1.00 92.90 ? 184 TYR L CG 1 +ATOM 22338 C CD1 . TYR L 1 184 ? 64.310 59.844 57.085 1.00 79.68 ? 184 TYR L CD1 1 +ATOM 22339 C CD2 . TYR L 1 184 ? 63.963 57.835 58.296 1.00 124.37 ? 184 TYR L CD2 1 +ATOM 22340 C CE1 . TYR L 1 184 ? 65.597 59.442 56.767 1.00 86.30 ? 184 TYR L CE1 1 +ATOM 22341 C CE2 . TYR L 1 184 ? 65.262 57.425 57.989 1.00 139.27 ? 184 TYR L CE2 1 +ATOM 22342 C CZ . TYR L 1 184 ? 66.078 58.232 57.222 1.00 102.56 ? 184 TYR L CZ 1 +ATOM 22343 O OH . TYR L 1 184 ? 67.379 57.821 56.957 1.00 67.39 ? 184 TYR L OH 1 +ATOM 22344 N N . GLU L 1 185 ? 60.757 61.127 55.895 1.00 158.38 ? 185 GLU L N 1 +ATOM 22345 C CA . GLU L 1 185 ? 60.806 62.061 54.772 1.00 171.00 ? 185 GLU L CA 1 +ATOM 22346 C C . GLU L 1 185 ? 61.298 63.424 55.225 1.00 165.72 ? 185 GLU L C 1 +ATOM 22347 O O . GLU L 1 185 ? 60.605 64.125 55.955 1.00 165.95 ? 185 GLU L O 1 +ATOM 22348 C CB . GLU L 1 185 ? 59.439 62.250 54.100 1.00 171.48 ? 185 GLU L CB 1 +ATOM 22349 C CG . GLU L 1 185 ? 58.614 60.997 53.909 1.00 183.13 ? 185 GLU L CG 1 +ATOM 22350 C CD . GLU L 1 185 ? 57.387 61.269 53.054 1.00 184.12 ? 185 GLU L CD 1 +ATOM 22351 O OE1 . GLU L 1 185 ? 57.178 62.439 52.663 1.00 164.23 ? 185 GLU L OE1 1 +ATOM 22352 O OE2 . GLU L 1 185 ? 56.651 60.310 52.751 1.00 208.57 ? 185 GLU L OE2 1 +ATOM 22353 N N . VAL L 1 186 ? 62.484 63.795 54.759 1.00 154.04 ? 186 VAL L N 1 +ATOM 22354 C CA . VAL L 1 186 ? 63.063 65.097 55.036 1.00 134.62 ? 186 VAL L CA 1 +ATOM 22355 C C . VAL L 1 186 ? 62.917 65.993 53.813 1.00 137.47 ? 186 VAL L C 1 +ATOM 22356 O O . VAL L 1 186 ? 63.085 65.547 52.679 1.00 149.62 ? 186 VAL L O 1 +ATOM 22357 C CB . VAL L 1 186 ? 64.549 64.966 55.396 1.00 129.80 ? 186 VAL L CB 1 +ATOM 22358 C CG1 . VAL L 1 186 ? 65.092 66.300 55.879 1.00 148.12 ? 186 VAL L CG1 1 +ATOM 22359 C CG2 . VAL L 1 186 ? 64.745 63.896 56.463 1.00 141.80 ? 186 VAL L CG2 1 +ATOM 22360 N N . GLN L 1 187 ? 62.577 67.254 54.048 1.00 148.42 ? 187 GLN L N 1 +ATOM 22361 C CA . GLN L 1 187 ? 62.321 68.184 52.959 1.00 161.35 ? 187 GLN L CA 1 +ATOM 22362 C C . GLN L 1 187 ? 62.721 69.594 53.352 1.00 178.98 ? 187 GLN L C 1 +ATOM 22363 O O . GLN L 1 187 ? 62.405 70.044 54.451 1.00 167.12 ? 187 GLN L O 1 +ATOM 22364 C CB . GLN L 1 187 ? 60.827 68.170 52.598 1.00 155.21 ? 187 GLN L CB 1 +ATOM 22365 C CG . GLN L 1 187 ? 60.407 67.097 51.613 1.00 155.25 ? 187 GLN L CG 1 +ATOM 22366 C CD . GLN L 1 187 ? 58.920 66.804 51.688 1.00 155.59 ? 187 GLN L CD 1 +ATOM 22367 O OE1 . GLN L 1 187 ? 58.107 67.718 51.858 1.00 111.77 ? 187 GLN L OE1 1 +ATOM 22368 N NE2 . GLN L 1 187 ? 58.554 65.522 51.575 1.00 162.51 ? 187 GLN L NE2 1 +ATOM 22369 N N . ALA L 1 188 ? 63.355 70.299 52.420 1.00 185.34 ? 188 ALA L N 1 +ATOM 22370 C CA . ALA L 1 188 ? 63.707 71.697 52.638 1.00 152.07 ? 188 ALA L CA 1 +ATOM 22371 C C . ALA L 1 188 ? 63.537 72.502 51.354 1.00 175.39 ? 188 ALA L C 1 +ATOM 22372 O O . ALA L 1 188 ? 63.806 72.009 50.259 1.00 208.22 ? 188 ALA L O 1 +ATOM 22373 C CB . ALA L 1 188 ? 65.129 71.795 53.140 1.00 123.58 ? 188 ALA L CB 1 +ATOM 22374 N N . GLY L 1 189 ? 63.023 73.716 51.480 1.00 181.43 ? 189 GLY L N 1 +ATOM 22375 C CA . GLY L 1 189 ? 62.778 74.568 50.324 1.00 202.27 ? 189 GLY L CA 1 +ATOM 22376 C C . GLY L 1 189 ? 63.031 76.035 50.617 1.00 203.54 ? 189 GLY L C 1 +ATOM 22377 O O . GLY L 1 189 ? 62.634 76.534 51.666 1.00 186.90 ? 189 GLY L O 1 +ATOM 22378 N N . VAL L 1 190 ? 63.662 76.724 49.670 1.00 193.07 ? 190 VAL L N 1 +ATOM 22379 C CA . VAL L 1 190 ? 63.879 78.159 49.766 1.00 165.55 ? 190 VAL L CA 1 +ATOM 22380 C C . VAL L 1 190 ? 63.088 78.895 48.667 1.00 169.76 ? 190 VAL L C 1 +ATOM 22381 O O . VAL L 1 190 ? 63.069 78.478 47.507 1.00 143.97 ? 190 VAL L O 1 +ATOM 22382 C CB . VAL L 1 190 ? 65.374 78.494 49.650 1.00 142.75 ? 190 VAL L CB 1 +ATOM 22383 C CG1 . VAL L 1 190 ? 65.615 79.947 50.026 1.00 141.32 ? 190 VAL L CG1 1 +ATOM 22384 C CG2 . VAL L 1 190 ? 66.200 77.560 50.522 1.00 129.24 ? 190 VAL L CG2 1 +ATOM 22385 N N . PHE L 1 191 ? 62.423 79.988 49.039 1.00 176.28 ? 191 PHE L N 1 +ATOM 22386 C CA . PHE L 1 191 ? 61.489 80.676 48.137 1.00 166.44 ? 191 PHE L CA 1 +ATOM 22387 C C . PHE L 1 191 ? 61.730 82.187 48.161 1.00 151.50 ? 191 PHE L C 1 +ATOM 22388 O O . PHE L 1 191 ? 61.815 82.776 49.251 1.00 200.13 ? 191 PHE L O 1 +ATOM 22389 C CB . PHE L 1 191 ? 60.038 80.351 48.543 1.00 172.42 ? 191 PHE L CB 1 +ATOM 22390 C CG . PHE L 1 191 ? 59.034 80.562 47.439 1.00 192.23 ? 191 PHE L CG 1 +ATOM 22391 C CD1 . PHE L 1 191 ? 58.699 81.841 47.021 1.00 179.81 ? 191 PHE L CD1 1 +ATOM 22392 C CD2 . PHE L 1 191 ? 58.429 79.480 46.814 1.00 207.52 ? 191 PHE L CD2 1 +ATOM 22393 C CE1 . PHE L 1 191 ? 57.775 82.039 46.008 1.00 158.66 ? 191 PHE L CE1 1 +ATOM 22394 C CE2 . PHE L 1 191 ? 57.517 79.671 45.788 1.00 190.51 ? 191 PHE L CE2 1 +ATOM 22395 C CZ . PHE L 1 191 ? 57.181 80.954 45.391 1.00 157.87 ? 191 PHE L CZ 1 +ATOM 22396 N N . LEU L 1 200 ? 63.010 83.253 42.670 1.00 148.99 ? 200 LEU L N 1 +ATOM 22397 C CA . LEU L 1 200 ? 63.860 82.179 43.159 1.00 153.15 ? 200 LEU L CA 1 +ATOM 22398 C C . LEU L 1 200 ? 63.057 81.171 43.970 1.00 199.12 ? 200 LEU L C 1 +ATOM 22399 O O . LEU L 1 200 ? 62.589 81.475 45.076 1.00 185.20 ? 200 LEU L O 1 +ATOM 22400 C CB . LEU L 1 200 ? 65.000 82.720 44.030 1.00 148.27 ? 200 LEU L CB 1 +ATOM 22401 C CG . LEU L 1 200 ? 65.833 81.635 44.737 1.00 151.82 ? 200 LEU L CG 1 +ATOM 22402 C CD1 . LEU L 1 200 ? 67.141 81.392 43.992 1.00 139.28 ? 200 LEU L CD1 1 +ATOM 22403 C CD2 . LEU L 1 200 ? 66.082 81.946 46.214 1.00 144.02 ? 200 LEU L CD2 1 +ATOM 22404 N N . GLU L 1 201 ? 62.956 79.953 43.439 1.00 232.28 ? 201 GLU L N 1 +ATOM 22405 C CA . GLU L 1 201 ? 62.595 78.785 44.241 1.00 229.82 ? 201 GLU L CA 1 +ATOM 22406 C C . GLU L 1 201 ? 63.695 77.729 44.181 1.00 213.00 ? 201 GLU L C 1 +ATOM 22407 O O . GLU L 1 201 ? 64.388 77.605 43.175 1.00 214.35 ? 201 GLU L O 1 +ATOM 22408 C CB . GLU L 1 201 ? 61.282 78.180 43.754 1.00 208.35 ? 201 GLU L CB 1 +ATOM 22409 C CG . GLU L 1 201 ? 60.619 77.296 44.796 1.00 214.79 ? 201 GLU L CG 1 +ATOM 22410 C CD . GLU L 1 201 ? 59.311 76.691 44.318 1.00 218.73 ? 201 GLU L CD 1 +ATOM 22411 O OE1 . GLU L 1 201 ? 58.442 77.445 43.826 1.00 219.03 ? 201 GLU L OE1 1 +ATOM 22412 O OE2 . GLU L 1 201 ? 59.135 75.461 44.470 1.00 218.96 ? 201 GLU L OE2 1 +ATOM 22413 N N . GLY L 1 202 ? 63.869 76.993 45.275 1.00 194.09 ? 202 GLY L N 1 +ATOM 22414 C CA . GLY L 1 202 ? 64.791 75.864 45.308 1.00 212.65 ? 202 GLY L CA 1 +ATOM 22415 C C . GLY L 1 202 ? 64.373 74.841 46.347 1.00 234.10 ? 202 GLY L C 1 +ATOM 22416 O O . GLY L 1 202 ? 64.180 75.179 47.515 1.00 265.15 ? 202 GLY L O 1 +ATOM 22417 N N . GLU L 1 203 ? 64.220 73.587 45.925 1.00 223.76 ? 203 GLU L N 1 +ATOM 22418 C CA . GLU L 1 203 ? 63.742 72.534 46.819 1.00 174.59 ? 203 GLU L CA 1 +ATOM 22419 C C . GLU L 1 203 ? 64.613 71.280 46.801 1.00 184.52 ? 203 GLU L C 1 +ATOM 22420 O O . GLU L 1 203 ? 65.012 70.790 45.740 1.00 188.00 ? 203 GLU L O 1 +ATOM 22421 C CB . GLU L 1 203 ? 62.304 72.160 46.475 1.00 147.28 ? 203 GLU L CB 1 +ATOM 22422 C CG . GLU L 1 203 ? 61.312 73.287 46.747 1.00 164.17 ? 203 GLU L CG 1 +ATOM 22423 C CD . GLU L 1 203 ? 59.852 72.907 46.509 1.00 190.19 ? 203 GLU L CD 1 +ATOM 22424 O OE1 . GLU L 1 203 ? 59.598 71.805 45.980 1.00 181.46 ? 203 GLU L OE1 1 +ATOM 22425 O OE2 . GLU L 1 203 ? 58.961 73.738 46.813 1.00 210.44 ? 203 GLU L OE2 1 +ATOM 22426 N N . VAL L 1 204 ? 64.884 70.764 47.995 1.00 179.04 ? 204 VAL L N 1 +ATOM 22427 C CA . VAL L 1 204 ? 65.539 69.471 48.170 1.00 145.04 ? 204 VAL L CA 1 +ATOM 22428 C C . VAL L 1 204 ? 64.633 68.571 49.011 1.00 142.81 ? 204 VAL L C 1 +ATOM 22429 O O . VAL L 1 204 ? 64.043 69.009 50.004 1.00 116.66 ? 204 VAL L O 1 +ATOM 22430 C CB . VAL L 1 204 ? 66.914 69.635 48.845 1.00 115.61 ? 204 VAL L CB 1 +ATOM 22431 C CG1 . VAL L 1 204 ? 67.443 68.306 49.377 1.00 117.05 ? 204 VAL L CG1 1 +ATOM 22432 C CG2 . VAL L 1 204 ? 67.893 70.253 47.864 1.00 104.35 ? 204 VAL L CG2 1 +ATOM 22433 N N . GLY L 1 205 ? 64.511 67.319 48.587 1.00 142.03 ? 205 GLY L N 1 +ATOM 22434 C CA . GLY L 1 205 ? 63.743 66.332 49.326 1.00 141.38 ? 205 GLY L CA 1 +ATOM 22435 C C . GLY L 1 205 ? 64.465 64.994 49.389 1.00 151.53 ? 205 GLY L C 1 +ATOM 22436 O O . GLY L 1 205 ? 65.217 64.634 48.478 1.00 183.06 ? 205 GLY L O 1 +ATOM 22437 N N . TYR L 1 206 ? 64.243 64.259 50.474 1.00 133.43 ? 206 TYR L N 1 +ATOM 22438 C CA . TYR L 1 206 ? 64.791 62.911 50.626 1.00 104.12 ? 206 TYR L CA 1 +ATOM 22439 C C . TYR L 1 206 ? 63.857 62.043 51.450 1.00 118.06 ? 206 TYR L C 1 +ATOM 22440 O O . TYR L 1 206 ? 63.235 62.523 52.387 1.00 122.48 ? 206 TYR L O 1 +ATOM 22441 C CB . TYR L 1 206 ? 66.139 62.956 51.321 1.00 97.23 ? 206 TYR L CB 1 +ATOM 22442 C CG . TYR L 1 206 ? 66.720 61.587 51.576 1.00 97.80 ? 206 TYR L CG 1 +ATOM 22443 C CD1 . TYR L 1 206 ? 67.312 60.850 50.548 1.00 108.46 ? 206 TYR L CD1 1 +ATOM 22444 C CD2 . TYR L 1 206 ? 66.674 61.020 52.838 1.00 97.62 ? 206 TYR L CD2 1 +ATOM 22445 C CE1 . TYR L 1 206 ? 67.848 59.590 50.780 1.00 103.85 ? 206 TYR L CE1 1 +ATOM 22446 C CE2 . TYR L 1 206 ? 67.221 59.765 53.082 1.00 101.35 ? 206 TYR L CE2 1 +ATOM 22447 C CZ . TYR L 1 206 ? 67.809 59.053 52.058 1.00 94.15 ? 206 TYR L CZ 1 +ATOM 22448 O OH . TYR L 1 206 ? 68.405 57.834 52.329 1.00 72.86 ? 206 TYR L OH 1 +ATOM 22449 N N . THR L 1 207 ? 63.711 60.779 51.062 1.00 144.94 ? 207 THR L N 1 +ATOM 22450 C CA . THR L 1 207 ? 62.832 59.851 51.782 1.00 135.77 ? 207 THR L CA 1 +ATOM 22451 C C . THR L 1 207 ? 63.511 58.499 51.919 1.00 133.97 ? 207 THR L C 1 +ATOM 22452 O O . THR L 1 207 ? 64.122 57.992 50.959 1.00 137.00 ? 207 THR L O 1 +ATOM 22453 C CB . THR L 1 207 ? 61.469 59.660 51.075 1.00 121.29 ? 207 THR L CB 1 +ATOM 22454 O OG1 . THR L 1 207 ? 61.674 59.109 49.771 1.00 118.85 ? 207 THR L OG1 1 +ATOM 22455 C CG2 . THR L 1 207 ? 60.742 60.983 50.925 1.00 138.63 ? 207 THR L CG2 1 +ATOM 22456 N N . SER L 1 208 ? 63.401 57.907 53.105 1.00 114.07 ? 208 SER L N 1 +ATOM 22457 C CA . SER L 1 208 ? 64.009 56.593 53.334 1.00 127.83 ? 208 SER L CA 1 +ATOM 22458 C C . SER L 1 208 ? 63.076 55.629 54.039 1.00 118.09 ? 208 SER L C 1 +ATOM 22459 O O . SER L 1 208 ? 62.515 55.953 55.084 1.00 93.16 ? 208 SER L O 1 +ATOM 22460 C CB . SER L 1 208 ? 65.301 56.712 54.137 1.00 148.20 ? 208 SER L CB 1 +ATOM 22461 O OG . SER L 1 208 ? 65.795 55.421 54.474 1.00 155.65 ? 208 SER L OG 1 +ATOM 22462 N N . ASN L 1 209 ? 62.895 54.458 53.421 1.00 126.00 ? 209 ASN L N 1 +ATOM 22463 C CA . ASN L 1 209 ? 62.127 53.358 53.998 1.00 100.14 ? 209 ASN L CA 1 +ATOM 22464 C C . ASN L 1 209 ? 63.066 52.225 54.312 1.00 90.41 ? 209 ASN L C 1 +ATOM 22465 O O . ASN L 1 209 ? 63.901 51.860 53.490 1.00 99.96 ? 209 ASN L O 1 +ATOM 22466 C CB . ASN L 1 209 ? 61.065 52.845 53.022 1.00 84.08 ? 209 ASN L CB 1 +ATOM 22467 C CG . ASN L 1 209 ? 59.936 53.820 52.825 1.00 93.58 ? 209 ASN L CG 1 +ATOM 22468 O OD1 . ASN L 1 209 ? 59.014 53.907 53.634 1.00 101.09 ? 209 ASN L OD1 1 +ATOM 22469 N ND2 . ASN L 1 209 ? 59.997 54.565 51.733 1.00 90.01 ? 209 ASN L ND2 1 +ATOM 22470 N N . GLU L 1 210 ? 62.891 51.637 55.477 1.00 75.83 ? 210 GLU L N 1 +ATOM 22471 C CA . GLU L 1 210 ? 63.513 50.364 55.744 1.00 81.16 ? 210 GLU L CA 1 +ATOM 22472 C C . GLU L 1 210 ? 62.891 49.307 54.834 1.00 86.81 ? 210 GLU L C 1 +ATOM 22473 O O . GLU L 1 210 ? 61.681 49.313 54.581 1.00 120.78 ? 210 GLU L O 1 +ATOM 22474 C CB . GLU L 1 210 ? 63.304 49.976 57.210 1.00 101.57 ? 210 GLU L CB 1 +ATOM 22475 C CG . GLU L 1 210 ? 64.540 49.432 57.912 1.00 121.95 ? 210 GLU L CG 1 +ATOM 22476 C CD . GLU L 1 210 ? 64.423 49.478 59.437 1.00 110.13 ? 210 GLU L CD 1 +ATOM 22477 O OE1 . GLU L 1 210 ? 63.675 50.322 59.990 1.00 75.59 ? 210 GLU L OE1 1 +ATOM 22478 O OE2 . GLU L 1 210 ? 65.100 48.658 60.081 1.00 106.32 ? 210 GLU L OE2 1 +ATOM 22479 N N . PRO L 1 211 ? 63.708 48.383 54.337 1.00 70.57 ? 211 PRO L N 1 +ATOM 22480 C CA . PRO L 1 211 ? 63.133 47.250 53.640 1.00 73.83 ? 211 PRO L CA 1 +ATOM 22481 C C . PRO L 1 211 ? 62.434 46.268 54.576 1.00 74.92 ? 211 PRO L C 1 +ATOM 22482 O O . PRO L 1 211 ? 63.052 45.788 55.538 1.00 66.74 ? 211 PRO L O 1 +ATOM 22483 C CB . PRO L 1 211 ? 64.353 46.596 52.969 1.00 70.98 ? 211 PRO L CB 1 +ATOM 22484 C CG . PRO L 1 211 ? 65.411 47.636 52.975 1.00 68.51 ? 211 PRO L CG 1 +ATOM 22485 C CD . PRO L 1 211 ? 65.165 48.395 54.237 1.00 69.51 ? 211 PRO L CD 1 +ATOM 22486 N N . VAL L 1 212 ? 61.154 45.989 54.296 1.00 76.58 ? 212 VAL L N 1 +ATOM 22487 C CA . VAL L 1 212 ? 60.378 45.029 55.078 1.00 88.17 ? 212 VAL L CA 1 +ATOM 22488 C C . VAL L 1 212 ? 60.988 43.631 54.951 1.00 100.90 ? 212 VAL L C 1 +ATOM 22489 O O . VAL L 1 212 ? 61.142 42.903 55.944 1.00 148.03 ? 212 VAL L O 1 +ATOM 22490 C CB . VAL L 1 212 ? 58.928 44.947 54.595 1.00 97.71 ? 212 VAL L CB 1 +ATOM 22491 C CG1 . VAL L 1 212 ? 58.110 44.053 55.521 1.00 102.50 ? 212 VAL L CG1 1 +ATOM 22492 C CG2 . VAL L 1 212 ? 58.298 46.338 54.502 1.00 109.57 ? 212 VAL L CG2 1 +ATOM 22493 N N . MET L 1 213 ? 61.349 43.292 53.722 1.00 98.58 ? 213 MET L N 1 +ATOM 22494 C CA . MET L 1 213 ? 62.298 42.225 53.394 1.00 109.51 ? 213 MET L CA 1 +ATOM 22495 C C . MET L 1 213 ? 63.439 41.988 54.411 1.00 104.04 ? 213 MET L C 1 +ATOM 22496 O O . MET L 1 213 ? 63.627 40.876 54.945 1.00 90.36 ? 213 MET L O 1 +ATOM 22497 C CB . MET L 1 213 ? 62.906 42.640 52.059 1.00 134.06 ? 213 MET L CB 1 +ATOM 22498 C CG . MET L 1 213 ? 63.821 41.664 51.375 1.00 144.45 ? 213 MET L CG 1 +ATOM 22499 S SD . MET L 1 213 ? 64.348 42.458 49.838 1.00 136.67 ? 213 MET L SD 1 +ATOM 22500 C CE . MET L 1 213 ? 66.050 42.702 50.281 1.00 110.80 ? 213 MET L CE 1 +ATOM 22501 N N . LEU L 1 214 ? 64.122 43.074 54.759 1.00 102.62 ? 214 LEU L N 1 +ATOM 22502 C CA . LEU L 1 214 ? 65.345 43.007 55.547 1.00 120.93 ? 214 LEU L CA 1 +ATOM 22503 C C . LEU L 1 214 ? 65.034 42.936 57.050 1.00 108.49 ? 214 LEU L C 1 +ATOM 22504 O O . LEU L 1 214 ? 65.771 42.320 57.826 1.00 95.12 ? 214 LEU L O 1 +ATOM 22505 C CB . LEU L 1 214 ? 66.214 44.232 55.252 1.00 134.25 ? 214 LEU L CB 1 +ATOM 22506 C CG . LEU L 1 214 ? 67.723 44.033 55.012 1.00 146.96 ? 214 LEU L CG 1 +ATOM 22507 C CD1 . LEU L 1 214 ? 68.024 43.093 53.828 1.00 135.26 ? 214 LEU L CD1 1 +ATOM 22508 C CD2 . LEU L 1 214 ? 68.373 45.402 54.811 1.00 136.90 ? 214 LEU L CD2 1 +ATOM 22509 N N . CYS L 1 215 ? 63.903 43.511 57.441 1.00 115.12 ? 215 CYS L N 1 +ATOM 22510 C CA . CYS L 1 215 ? 63.401 43.421 58.826 1.00 122.36 ? 215 CYS L CA 1 +ATOM 22511 C C . CYS L 1 215 ? 62.852 42.032 59.182 1.00 99.54 ? 215 CYS L C 1 +ATOM 22512 O O . CYS L 1 215 ? 63.141 41.482 60.261 1.00 101.23 ? 215 CYS L O 1 +ATOM 22513 C CB . CYS L 1 215 ? 62.263 44.408 59.045 1.00 118.15 ? 215 CYS L CB 1 +ATOM 22514 S SG . CYS L 1 215 ? 62.761 46.121 58.879 1.00 82.02 ? 215 CYS L SG 1 +ATOM 22515 N N . LEU L 1 216 ? 62.091 41.471 58.254 1.00 63.73 ? 216 LEU L N 1 +ATOM 22516 C CA . LEU L 1 216 ? 61.739 40.082 58.348 1.00 66.63 ? 216 LEU L CA 1 +ATOM 22517 C C . LEU L 1 216 ? 62.992 39.212 58.578 1.00 73.31 ? 216 LEU L C 1 +ATOM 22518 O O . LEU L 1 216 ? 63.010 38.348 59.474 1.00 96.56 ? 216 LEU L O 1 +ATOM 22519 C CB . LEU L 1 216 ? 60.992 39.613 57.082 1.00 64.72 ? 216 LEU L CB 1 +ATOM 22520 C CG . LEU L 1 216 ? 60.542 38.154 57.072 1.00 54.62 ? 216 LEU L CG 1 +ATOM 22521 C CD1 . LEU L 1 216 ? 59.654 37.824 58.253 1.00 74.43 ? 216 LEU L CD1 1 +ATOM 22522 C CD2 . LEU L 1 216 ? 59.820 37.835 55.807 1.00 51.19 ? 216 LEU L CD2 1 +ATOM 22523 N N . MET L 1 217 ? 64.018 39.392 57.737 1.00 71.15 ? 217 MET L N 1 +ATOM 22524 C CA . MET L 1 217 ? 65.198 38.538 57.784 1.00 80.03 ? 217 MET L CA 1 +ATOM 22525 C C . MET L 1 217 ? 65.876 38.674 59.145 1.00 74.43 ? 217 MET L C 1 +ATOM 22526 O O . MET L 1 217 ? 66.200 37.678 59.798 1.00 73.48 ? 217 MET L O 1 +ATOM 22527 C CB . MET L 1 217 ? 66.166 38.868 56.651 1.00 89.18 ? 217 MET L CB 1 +ATOM 22528 C CG . MET L 1 217 ? 66.764 37.630 55.988 1.00 126.07 ? 217 MET L CG 1 +ATOM 22529 S SD . MET L 1 217 ? 67.922 36.735 57.061 1.00 174.55 ? 217 MET L SD 1 +ATOM 22530 C CE . MET L 1 217 ? 68.231 35.219 56.143 1.00 135.08 ? 217 MET L CE 1 +ATOM 22531 N N . SER L 1 218 ? 66.012 39.908 59.598 1.00 81.85 ? 218 SER L N 1 +ATOM 22532 C CA . SER L 1 218 ? 66.630 40.203 60.892 1.00 88.85 ? 218 SER L CA 1 +ATOM 22533 C C . SER L 1 218 ? 65.903 39.487 62.007 1.00 68.97 ? 218 SER L C 1 +ATOM 22534 O O . SER L 1 218 ? 66.520 38.847 62.859 1.00 83.15 ? 218 SER L O 1 +ATOM 22535 C CB . SER L 1 218 ? 66.615 41.721 61.141 1.00 110.77 ? 218 SER L CB 1 +ATOM 22536 O OG . SER L 1 218 ? 67.386 42.081 62.263 1.00 88.77 ? 218 SER L OG 1 +ATOM 22537 N N . ALA L 1 219 ? 64.589 39.637 62.025 1.00 63.82 ? 219 ALA L N 1 +ATOM 22538 C CA . ALA L 1 219 ? 63.785 39.095 63.111 1.00 87.87 ? 219 ALA L CA 1 +ATOM 22539 C C . ALA L 1 219 ? 63.850 37.559 63.163 1.00 72.76 ? 219 ALA L C 1 +ATOM 22540 O O . ALA L 1 219 ? 63.822 36.948 64.233 1.00 49.78 ? 219 ALA L O 1 +ATOM 22541 C CB . ALA L 1 219 ? 62.342 39.577 62.966 1.00 121.41 ? 219 ALA L CB 1 +ATOM 22542 N N . ILE L 1 220 ? 63.949 36.940 61.996 1.00 82.81 ? 220 ILE L N 1 +ATOM 22543 C CA . ILE L 1 220 ? 64.041 35.483 61.923 1.00 87.28 ? 220 ILE L CA 1 +ATOM 22544 C C . ILE L 1 220 ? 65.381 34.991 62.476 1.00 89.01 ? 220 ILE L C 1 +ATOM 22545 O O . ILE L 1 220 ? 65.426 34.029 63.238 1.00 76.90 ? 220 ILE L O 1 +ATOM 22546 C CB . ILE L 1 220 ? 63.862 34.977 60.475 1.00 84.89 ? 220 ILE L CB 1 +ATOM 22547 C CG1 . ILE L 1 220 ? 62.397 35.180 60.029 1.00 78.29 ? 220 ILE L CG1 1 +ATOM 22548 C CG2 . ILE L 1 220 ? 64.274 33.511 60.366 1.00 84.27 ? 220 ILE L CG2 1 +ATOM 22549 C CD1 . ILE L 1 220 ? 62.184 35.087 58.534 1.00 74.63 ? 220 ILE L CD1 1 +ATOM 22550 N N . GLU L 1 221 ? 66.458 35.695 62.148 1.00 99.73 ? 221 GLU L N 1 +ATOM 22551 C CA . GLU L 1 221 ? 67.768 35.419 62.751 1.00 96.81 ? 221 GLU L CA 1 +ATOM 22552 C C . GLU L 1 221 ? 67.720 35.477 64.297 1.00 71.16 ? 221 GLU L C 1 +ATOM 22553 O O . GLU L 1 221 ? 68.122 34.534 64.972 1.00 47.96 ? 221 GLU L O 1 +ATOM 22554 C CB . GLU L 1 221 ? 68.810 36.420 62.225 1.00 123.37 ? 221 GLU L CB 1 +ATOM 22555 C CG . GLU L 1 221 ? 69.205 36.183 60.777 1.00 138.79 ? 221 GLU L CG 1 +ATOM 22556 C CD . GLU L 1 221 ? 69.908 37.374 60.133 1.00 143.23 ? 221 GLU L CD 1 +ATOM 22557 O OE1 . GLU L 1 221 ? 69.544 38.548 60.417 1.00 100.00 ? 221 GLU L OE1 1 +ATOM 22558 O OE2 . GLU L 1 221 ? 70.801 37.106 59.296 1.00 131.80 ? 221 GLU L OE2 1 +ATOM 22559 N N . THR L 1 222 ? 67.216 36.598 64.822 1.00 53.34 ? 222 THR L N 1 +ATOM 22560 C CA . THR L 1 222 ? 67.006 36.808 66.247 1.00 42.39 ? 222 THR L CA 1 +ATOM 22561 C C . THR L 1 222 ? 66.240 35.659 66.883 1.00 41.21 ? 222 THR L C 1 +ATOM 22562 O O . THR L 1 222 ? 66.667 35.118 67.903 1.00 44.31 ? 222 THR L O 1 +ATOM 22563 C CB . THR L 1 222 ? 66.199 38.096 66.480 1.00 46.97 ? 222 THR L CB 1 +ATOM 22564 O OG1 . THR L 1 222 ? 67.014 39.250 66.179 1.00 47.36 ? 222 THR L OG1 1 +ATOM 22565 C CG2 . THR L 1 222 ? 65.656 38.161 67.916 1.00 51.38 ? 222 THR L CG2 1 +ATOM 22566 N N . GLY L 1 223 ? 65.117 35.292 66.277 1.00 47.52 ? 223 GLY L N 1 +ATOM 22567 C CA . GLY L 1 223 ? 64.382 34.113 66.684 1.00 65.86 ? 223 GLY L CA 1 +ATOM 22568 C C . GLY L 1 223 ? 65.225 32.824 66.759 1.00 88.48 ? 223 GLY L C 1 +ATOM 22569 O O . GLY L 1 223 ? 65.075 32.020 67.696 1.00 79.97 ? 223 GLY L O 1 +ATOM 22570 N N . VAL L 1 224 ? 66.089 32.611 65.769 1.00 87.71 ? 224 VAL L N 1 +ATOM 22571 C CA . VAL L 1 224 ? 66.912 31.417 65.741 1.00 82.64 ? 224 VAL L CA 1 +ATOM 22572 C C . VAL L 1 224 ? 67.871 31.417 66.931 1.00 77.42 ? 224 VAL L C 1 +ATOM 22573 O O . VAL L 1 224 ? 68.064 30.393 67.589 1.00 93.22 ? 224 VAL L O 1 +ATOM 22574 C CB . VAL L 1 224 ? 67.726 31.315 64.451 1.00 87.58 ? 224 VAL L CB 1 +ATOM 22575 C CG1 . VAL L 1 224 ? 68.726 30.167 64.538 1.00 87.97 ? 224 VAL L CG1 1 +ATOM 22576 C CG2 . VAL L 1 224 ? 66.807 31.134 63.259 1.00 80.52 ? 224 VAL L CG2 1 +ATOM 22577 N N . ILE L 1 225 ? 68.439 32.571 67.236 1.00 70.80 ? 225 ILE L N 1 +ATOM 22578 C CA . ILE L 1 225 ? 69.318 32.682 68.398 1.00 81.98 ? 225 ILE L CA 1 +ATOM 22579 C C . ILE L 1 225 ? 68.554 32.296 69.666 1.00 79.61 ? 225 ILE L C 1 +ATOM 22580 O O . ILE L 1 225 ? 69.044 31.486 70.448 1.00 60.32 ? 225 ILE L O 1 +ATOM 22581 C CB . ILE L 1 225 ? 69.936 34.100 68.537 1.00 85.14 ? 225 ILE L CB 1 +ATOM 22582 C CG1 . ILE L 1 225 ? 70.910 34.356 67.384 1.00 92.38 ? 225 ILE L CG1 1 +ATOM 22583 C CG2 . ILE L 1 225 ? 70.671 34.248 69.853 1.00 68.07 ? 225 ILE L CG2 1 +ATOM 22584 C CD1 . ILE L 1 225 ? 71.227 35.823 67.170 1.00 109.96 ? 225 ILE L CD1 1 +ATOM 22585 N N . PHE L 1 226 ? 67.387 32.920 69.889 1.00 83.81 ? 226 PHE L N 1 +ATOM 22586 C CA . PHE L 1 226 ? 66.585 32.671 71.107 1.00 75.10 ? 226 PHE L CA 1 +ATOM 22587 C C . PHE L 1 226 ? 66.252 31.194 71.210 1.00 69.50 ? 226 PHE L C 1 +ATOM 22588 O O . PHE L 1 226 ? 66.148 30.654 72.306 1.00 73.26 ? 226 PHE L O 1 +ATOM 22589 C CB . PHE L 1 226 ? 65.292 33.506 71.121 1.00 69.12 ? 226 PHE L CB 1 +ATOM 22590 C CG . PHE L 1 226 ? 65.473 34.931 71.569 1.00 79.02 ? 226 PHE L CG 1 +ATOM 22591 C CD1 . PHE L 1 226 ? 66.031 35.221 72.808 1.00 95.54 ? 226 PHE L CD1 1 +ATOM 22592 C CD2 . PHE L 1 226 ? 65.075 35.993 70.760 1.00 78.04 ? 226 PHE L CD2 1 +ATOM 22593 C CE1 . PHE L 1 226 ? 66.212 36.539 73.222 1.00 92.46 ? 226 PHE L CE1 1 +ATOM 22594 C CE2 . PHE L 1 226 ? 65.249 37.305 71.180 1.00 79.23 ? 226 PHE L CE2 1 +ATOM 22595 C CZ . PHE L 1 226 ? 65.814 37.576 72.411 1.00 77.23 ? 226 PHE L CZ 1 +ATOM 22596 N N . LEU L 1 227 ? 66.081 30.547 70.064 1.00 76.79 ? 227 LEU L N 1 +ATOM 22597 C CA . LEU L 1 227 ? 65.783 29.111 70.033 1.00 81.28 ? 227 LEU L CA 1 +ATOM 22598 C C . LEU L 1 227 ? 66.981 28.302 70.492 1.00 64.65 ? 227 LEU L C 1 +ATOM 22599 O O . LEU L 1 227 ? 66.835 27.387 71.268 1.00 65.03 ? 227 LEU L O 1 +ATOM 22600 C CB . LEU L 1 227 ? 65.354 28.712 68.624 1.00 82.14 ? 227 LEU L CB 1 +ATOM 22601 C CG . LEU L 1 227 ? 63.922 29.084 68.204 1.00 75.82 ? 227 LEU L CG 1 +ATOM 22602 C CD1 . LEU L 1 227 ? 63.631 28.947 66.726 1.00 82.62 ? 227 LEU L CD1 1 +ATOM 22603 C CD2 . LEU L 1 227 ? 62.912 28.269 68.989 1.00 88.11 ? 227 LEU L CD2 1 +ATOM 22604 N N . ILE L 1 228 ? 68.163 28.675 70.030 1.00 63.02 ? 228 ILE L N 1 +ATOM 22605 C CA . ILE L 1 228 ? 69.358 27.945 70.377 1.00 71.73 ? 228 ILE L CA 1 +ATOM 22606 C C . ILE L 1 228 ? 69.584 28.106 71.859 1.00 69.85 ? 228 ILE L C 1 +ATOM 22607 O O . ILE L 1 228 ? 69.934 27.156 72.569 1.00 59.06 ? 228 ILE L O 1 +ATOM 22608 C CB . ILE L 1 228 ? 70.600 28.439 69.589 1.00 99.33 ? 228 ILE L CB 1 +ATOM 22609 C CG1 . ILE L 1 228 ? 70.442 28.150 68.094 1.00 103.89 ? 228 ILE L CG1 1 +ATOM 22610 C CG2 . ILE L 1 228 ? 71.866 27.739 70.076 1.00 113.49 ? 228 ILE L CG2 1 +ATOM 22611 C CD1 . ILE L 1 228 ? 71.413 28.895 67.204 1.00 109.20 ? 228 ILE L CD1 1 +ATOM 22612 N N . ASN L 1 229 ? 69.533 29.349 72.315 1.00 79.29 ? 229 ASN L N 1 +ATOM 22613 C CA . ASN L 1 229 ? 69.841 29.654 73.721 1.00 86.67 ? 229 ASN L CA 1 +ATOM 22614 C C . ASN L 1 229 ? 68.868 28.865 74.586 1.00 65.13 ? 229 ASN L C 1 +ATOM 22615 O O . ASN L 1 229 ? 69.246 28.338 75.638 1.00 86.96 ? 229 ASN L O 1 +ATOM 22616 C CB . ASN L 1 229 ? 69.746 31.179 73.971 1.00 86.65 ? 229 ASN L CB 1 +ATOM 22617 C CG . ASN L 1 229 ? 70.329 31.603 75.300 1.00 64.30 ? 229 ASN L CG 1 +ATOM 22618 O OD1 . ASN L 1 229 ? 71.247 30.961 75.835 1.00 53.31 ? 229 ASN L OD1 1 +ATOM 22619 N ND2 . ASN L 1 229 ? 69.860 32.746 75.790 1.00 58.44 ? 229 ASN L ND2 1 +ATOM 22620 N N . ASP L 1 230 ? 67.612 28.841 74.159 1.00 50.31 ? 230 ASP L N 1 +ATOM 22621 C CA . ASP L 1 230 ? 66.571 28.200 74.932 1.00 62.84 ? 230 ASP L CA 1 +ATOM 22622 C C . ASP L 1 230 ? 66.859 26.712 75.004 1.00 54.77 ? 230 ASP L C 1 +ATOM 22623 O O . ASP L 1 230 ? 66.660 26.078 76.037 1.00 55.40 ? 230 ASP L O 1 +ATOM 22624 C CB . ASP L 1 230 ? 65.204 28.462 74.286 1.00 73.10 ? 230 ASP L CB 1 +ATOM 22625 C CG . ASP L 1 230 ? 64.048 27.873 75.089 1.00 76.86 ? 230 ASP L CG 1 +ATOM 22626 O OD1 . ASP L 1 230 ? 63.715 28.448 76.144 1.00 85.19 ? 230 ASP L OD1 1 +ATOM 22627 O OD2 . ASP L 1 230 ? 63.461 26.861 74.670 1.00 76.42 ? 230 ASP L OD2 1 +ATOM 22628 N N . GLY L 1 231 ? 67.328 26.178 73.900 1.00 50.34 ? 231 GLY L N 1 +ATOM 22629 C CA . GLY L 1 231 ? 67.595 24.766 73.819 1.00 54.99 ? 231 GLY L CA 1 +ATOM 22630 C C . GLY L 1 231 ? 68.783 24.416 74.677 1.00 64.71 ? 231 GLY L C 1 +ATOM 22631 O O . GLY L 1 231 ? 68.851 23.309 75.238 1.00 90.63 ? 231 GLY L O 1 +ATOM 22632 N N . ILE L 1 232 ? 69.748 25.332 74.755 1.00 74.93 ? 232 ILE L N 1 +ATOM 22633 C CA . ILE L 1 232 ? 70.924 25.139 75.616 1.00 98.32 ? 232 ILE L CA 1 +ATOM 22634 C C . ILE L 1 232 ? 70.468 25.000 77.066 1.00 111.85 ? 232 ILE L C 1 +ATOM 22635 O O . ILE L 1 232 ? 70.863 24.066 77.762 1.00 78.54 ? 232 ILE L O 1 +ATOM 22636 C CB . ILE L 1 232 ? 71.949 26.311 75.476 1.00 109.31 ? 232 ILE L CB 1 +ATOM 22637 C CG1 . ILE L 1 232 ? 72.694 26.196 74.144 1.00 98.51 ? 232 ILE L CG1 1 +ATOM 22638 C CG2 . ILE L 1 232 ? 72.950 26.330 76.636 1.00 129.88 ? 232 ILE L CG2 1 +ATOM 22639 C CD1 . ILE L 1 232 ? 73.390 27.472 73.716 1.00 97.51 ? 232 ILE L CD1 1 +ATOM 22640 N N . ASP L 1 233 ? 69.647 25.954 77.514 1.00 141.13 ? 233 ASP L N 1 +ATOM 22641 C CA . ASP L 1 233 ? 69.086 25.941 78.869 1.00 111.95 ? 233 ASP L CA 1 +ATOM 22642 C C . ASP L 1 233 ? 68.340 24.644 79.148 1.00 102.70 ? 233 ASP L C 1 +ATOM 22643 O O . ASP L 1 233 ? 68.570 24.000 80.171 1.00 140.22 ? 233 ASP L O 1 +ATOM 22644 C CB . ASP L 1 233 ? 68.130 27.120 79.077 1.00 89.75 ? 233 ASP L CB 1 +ATOM 22645 C CG . ASP L 1 233 ? 68.836 28.462 79.052 1.00 96.96 ? 233 ASP L CG 1 +ATOM 22646 O OD1 . ASP L 1 233 ? 70.039 28.544 78.637 1.00 96.01 ? 233 ASP L OD1 1 +ATOM 22647 O OD2 . ASP L 1 233 ? 68.155 29.488 79.355 1.00 89.52 ? 233 ASP L OD2 1 +ATOM 22648 N N . ARG L 1 234 ? 67.448 24.269 78.246 1.00 90.98 ? 234 ARG L N 1 +ATOM 22649 C CA . ARG L 1 234 ? 66.578 23.129 78.482 1.00 88.36 ? 234 ARG L CA 1 +ATOM 22650 C C . ARG L 1 234 ? 67.245 21.767 78.279 1.00 83.10 ? 234 ARG L C 1 +ATOM 22651 O O . ARG L 1 234 ? 66.590 20.723 78.396 1.00 73.68 ? 234 ARG L O 1 +ATOM 22652 C CB . ARG L 1 234 ? 65.316 23.270 77.625 1.00 80.30 ? 234 ARG L CB 1 +ATOM 22653 C CG . ARG L 1 234 ? 64.407 24.345 78.173 1.00 92.05 ? 234 ARG L CG 1 +ATOM 22654 C CD . ARG L 1 234 ? 63.449 24.879 77.130 1.00 111.61 ? 234 ARG L CD 1 +ATOM 22655 N NE . ARG L 1 234 ? 62.680 26.027 77.632 1.00 115.30 ? 234 ARG L NE 1 +ATOM 22656 C CZ . ARG L 1 234 ? 61.352 26.108 77.645 1.00 105.44 ? 234 ARG L CZ 1 +ATOM 22657 N NH1 . ARG L 1 234 ? 60.617 25.074 77.220 1.00 128.71 ? 234 ARG L NH1 1 +ATOM 22658 N NH2 . ARG L 1 234 ? 60.760 27.214 78.088 1.00 70.31 ? 234 ARG L NH2 1 +ATOM 22659 N N . GLY L 1 235 ? 68.512 21.765 77.871 1.00 94.43 ? 235 GLY L N 1 +ATOM 22660 C CA . GLY L 1 235 ? 69.212 20.505 77.585 1.00 108.02 ? 235 GLY L CA 1 +ATOM 22661 C C . GLY L 1 235 ? 68.772 19.745 76.314 1.00 87.47 ? 235 GLY L C 1 +ATOM 22662 O O . GLY L 1 235 ? 68.837 18.531 76.272 1.00 50.32 ? 235 GLY L O 1 +ATOM 22663 N N . LEU L 1 236 ? 68.397 20.474 75.261 1.00 83.45 ? 236 LEU L N 1 +ATOM 22664 C CA . LEU L 1 236 ? 68.275 19.887 73.923 1.00 66.01 ? 236 LEU L CA 1 +ATOM 22665 C C . LEU L 1 236 ? 69.655 19.636 73.319 1.00 65.42 ? 236 LEU L C 1 +ATOM 22666 O O . LEU L 1 236 ? 69.951 18.530 72.889 1.00 70.70 ? 236 LEU L O 1 +ATOM 22667 C CB . LEU L 1 236 ? 67.492 20.807 72.987 1.00 87.85 ? 236 LEU L CB 1 +ATOM 22668 C CG . LEU L 1 236 ? 65.954 20.778 73.051 1.00 104.10 ? 236 LEU L CG 1 +ATOM 22669 C CD1 . LEU L 1 236 ? 65.462 21.603 74.233 1.00 134.66 ? 236 LEU L CD1 1 +ATOM 22670 C CD2 . LEU L 1 236 ? 65.357 21.318 71.767 1.00 91.06 ? 236 LEU L CD2 1 +ATOM 22671 N N . TRP L 1 237 ? 70.527 20.648 73.359 1.00 67.00 ? 237 TRP L N 1 +ATOM 22672 C CA . TRP L 1 237 ? 71.910 20.540 72.851 1.00 71.28 ? 237 TRP L CA 1 +ATOM 22673 C C . TRP L 1 237 ? 72.928 21.275 73.755 1.00 82.98 ? 237 TRP L C 1 +ATOM 22674 O O . TRP L 1 237 ? 72.539 21.938 74.707 1.00 90.41 ? 237 TRP L O 1 +ATOM 22675 C CB . TRP L 1 237 ? 71.969 21.143 71.473 1.00 62.37 ? 237 TRP L CB 1 +ATOM 22676 C CG . TRP L 1 237 ? 71.073 22.289 71.317 1.00 63.08 ? 237 TRP L CG 1 +ATOM 22677 C CD1 . TRP L 1 237 ? 71.206 23.503 71.907 1.00 75.29 ? 237 TRP L CD1 1 +ATOM 22678 C CD2 . TRP L 1 237 ? 69.893 22.368 70.499 1.00 76.91 ? 237 TRP L CD2 1 +ATOM 22679 N NE1 . TRP L 1 237 ? 70.177 24.336 71.519 1.00 81.14 ? 237 TRP L NE1 1 +ATOM 22680 C CE2 . TRP L 1 237 ? 69.357 23.659 70.657 1.00 88.19 ? 237 TRP L CE2 1 +ATOM 22681 C CE3 . TRP L 1 237 ? 69.229 21.472 69.655 1.00 98.11 ? 237 TRP L CE3 1 +ATOM 22682 C CZ2 . TRP L 1 237 ? 68.173 24.074 70.005 1.00 106.17 ? 237 TRP L CZ2 1 +ATOM 22683 C CZ3 . TRP L 1 237 ? 68.030 21.883 69.012 1.00 89.63 ? 237 TRP L CZ3 1 +ATOM 22684 C CH2 . TRP L 1 237 ? 67.525 23.165 69.198 1.00 94.59 ? 237 TRP L CH2 1 +ATOM 22685 N N . ASP L 1 238 ? 74.228 21.040 73.565 1.00 96.87 ? 238 ASP L N 1 +ATOM 22686 C CA . ASP L 1 238 ? 75.266 21.654 74.462 1.00 100.51 ? 238 ASP L CA 1 +ATOM 22687 C C . ASP L 1 238 ? 76.482 22.174 73.757 1.00 85.51 ? 238 ASP L C 1 +ATOM 22688 O O . ASP L 1 238 ? 76.838 21.713 72.660 1.00 89.66 ? 238 ASP L O 1 +ATOM 22689 C CB . ASP L 1 238 ? 75.645 20.796 75.695 1.00 107.35 ? 238 ASP L CB 1 +ATOM 22690 C CG . ASP L 1 238 ? 75.353 21.524 76.990 1.00 102.05 ? 238 ASP L CG 1 +ATOM 22691 O OD1 . ASP L 1 238 ? 75.648 22.736 77.185 1.00 79.31 ? 238 ASP L OD1 1 +ATOM 22692 O OD2 . ASP L 1 238 ? 74.843 20.837 77.813 1.00 110.04 ? 238 ASP L OD2 1 +ATOM 22693 N N . LEU L 1 239 ? 77.154 23.067 74.475 1.00 75.52 ? 239 LEU L N 1 +ATOM 22694 C CA . LEU L 1 239 ? 78.279 23.796 73.945 1.00 80.89 ? 239 LEU L CA 1 +ATOM 22695 C C . LEU L 1 239 ? 79.549 22.963 73.928 1.00 87.21 ? 239 LEU L C 1 +ATOM 22696 O O . LEU L 1 239 ? 79.786 22.140 74.829 1.00 114.28 ? 239 LEU L O 1 +ATOM 22697 C CB . LEU L 1 239 ? 78.534 25.066 74.762 1.00 69.08 ? 239 LEU L CB 1 +ATOM 22698 C CG . LEU L 1 239 ? 77.585 26.242 74.607 1.00 64.53 ? 239 LEU L CG 1 +ATOM 22699 C CD1 . LEU L 1 239 ? 78.092 27.435 75.400 1.00 48.74 ? 239 LEU L CD1 1 +ATOM 22700 C CD2 . LEU L 1 239 ? 77.451 26.608 73.149 1.00 77.60 ? 239 LEU L CD2 1 +ATOM 22701 N N . GLN L 1 240 ? 80.367 23.184 72.905 1.00 79.55 ? 240 GLN L N 1 +ATOM 22702 C CA . GLN L 1 240 ? 81.707 22.599 72.852 1.00 87.39 ? 240 GLN L CA 1 +ATOM 22703 C C . GLN L 1 240 ? 82.536 23.008 74.066 1.00 76.13 ? 240 GLN L C 1 +ATOM 22704 O O . GLN L 1 240 ? 83.001 22.154 74.830 1.00 75.78 ? 240 GLN L O 1 +ATOM 22705 C CB . GLN L 1 240 ? 82.429 23.049 71.585 1.00 108.45 ? 240 GLN L CB 1 +ATOM 22706 C CG . GLN L 1 240 ? 83.768 22.356 71.340 1.00 112.40 ? 240 GLN L CG 1 +ATOM 22707 C CD . GLN L 1 240 ? 83.592 20.869 71.075 1.00 121.75 ? 240 GLN L CD 1 +ATOM 22708 O OE1 . GLN L 1 240 ? 83.279 20.465 69.955 1.00 116.89 ? 240 GLN L OE1 1 +ATOM 22709 N NE2 . GLN L 1 240 ? 83.769 20.048 72.111 1.00 130.74 ? 240 GLN L NE2 1 +ATOM 22710 N N . ASN L 1 241 ? 82.640 24.314 74.274 1.00 78.83 ? 241 ASN L N 1 +ATOM 22711 C CA . ASN L 1 241 ? 83.351 24.879 75.424 1.00 111.58 ? 241 ASN L CA 1 +ATOM 22712 C C . ASN L 1 241 ? 82.406 25.397 76.499 1.00 139.21 ? 241 ASN L C 1 +ATOM 22713 O O . ASN L 1 241 ? 81.661 26.375 76.267 1.00 176.49 ? 241 ASN L O 1 +ATOM 22714 C CB . ASN L 1 241 ? 84.206 26.040 74.968 1.00 133.46 ? 241 ASN L CB 1 +ATOM 22715 C CG . ASN L 1 241 ? 85.646 25.662 74.813 1.00 167.00 ? 241 ASN L CG 1 +ATOM 22716 O OD1 . ASN L 1 241 ? 86.466 25.978 75.671 1.00 176.85 ? 241 ASN L OD1 1 +ATOM 22717 N ND2 . ASN L 1 241 ? 85.970 24.962 73.727 1.00 202.99 ? 241 ASN L ND2 1 +ATOM 22718 N N . LYS L 1 242 ? 82.394 24.731 77.658 1.00 133.42 ? 242 LYS L N 1 +ATOM 22719 C CA . LYS L 1 242 ? 81.443 25.133 78.716 1.00 113.02 ? 242 LYS L CA 1 +ATOM 22720 C C . LYS L 1 242 ? 81.879 26.471 79.200 1.00 89.74 ? 242 LYS L C 1 +ATOM 22721 O O . LYS L 1 242 ? 81.066 27.164 79.806 1.00 110.39 ? 242 LYS L O 1 +ATOM 22722 C CB . LYS L 1 242 ? 81.426 24.274 79.969 1.00 113.46 ? 242 LYS L CB 1 +ATOM 22723 C CG . LYS L 1 242 ? 82.434 23.162 79.951 1.00 116.36 ? 242 LYS L CG 1 +ATOM 22724 C CD . LYS L 1 242 ? 81.937 21.903 80.645 1.00 133.10 ? 242 LYS L CD 1 +ATOM 22725 C CE . LYS L 1 242 ? 82.257 20.670 79.818 1.00 160.31 ? 242 LYS L CE 1 +ATOM 22726 N NZ . LYS L 1 242 ? 81.935 19.413 80.542 1.00 192.33 ? 242 LYS L NZ 1 +ATOM 22727 N N . ALA L 1 243 ? 83.174 26.766 79.030 1.00 66.97 ? 243 ALA L N 1 +ATOM 22728 C CA . ALA L 1 243 ? 83.759 28.077 79.378 1.00 69.74 ? 243 ALA L CA 1 +ATOM 22729 C C . ALA L 1 243 ? 83.140 29.197 78.561 1.00 94.55 ? 243 ALA L C 1 +ATOM 22730 O O . ALA L 1 243 ? 83.159 30.359 78.981 1.00 112.62 ? 243 ALA L O 1 +ATOM 22731 C CB . ALA L 1 243 ? 85.242 28.076 79.140 1.00 48.74 ? 243 ALA L CB 1 +ATOM 22732 N N . GLU L 1 244 ? 82.476 28.839 77.462 1.00 99.28 ? 244 GLU L N 1 +ATOM 22733 C CA . GLU L 1 244 ? 81.844 29.842 76.619 1.00 91.71 ? 244 GLU L CA 1 +ATOM 22734 C C . GLU L 1 244 ? 80.377 30.117 76.947 1.00 70.02 ? 244 GLU L C 1 +ATOM 22735 O O . GLU L 1 244 ? 79.675 30.735 76.156 1.00 94.90 ? 244 GLU L O 1 +ATOM 22736 C CB . GLU L 1 244 ? 82.002 29.441 75.146 1.00 128.16 ? 244 GLU L CB 1 +ATOM 22737 C CG . GLU L 1 244 ? 83.433 29.580 74.617 1.00 129.77 ? 244 GLU L CG 1 +ATOM 22738 C CD . GLU L 1 244 ? 83.543 29.445 73.110 1.00 120.21 ? 244 GLU L CD 1 +ATOM 22739 O OE1 . GLU L 1 244 ? 83.439 28.302 72.601 1.00 129.47 ? 244 GLU L OE1 1 +ATOM 22740 O OE2 . GLU L 1 244 ? 83.658 30.494 72.441 1.00 106.09 ? 244 GLU L OE2 1 +ATOM 22741 N N . ARG L 1 245 ? 79.902 29.579 78.060 1.00 65.95 ? 245 ARG L N 1 +ATOM 22742 C CA . ARG L 1 245 ? 78.547 29.807 78.578 1.00 82.31 ? 245 ARG L CA 1 +ATOM 22743 C C . ARG L 1 245 ? 78.256 31.328 78.720 1.00 74.96 ? 245 ARG L C 1 +ATOM 22744 O O . ARG L 1 245 ? 77.133 31.824 78.362 1.00 95.57 ? 245 ARG L O 1 +ATOM 22745 C CB . ARG L 1 245 ? 78.414 29.024 79.982 1.00 94.17 ? 245 ARG L CB 1 +ATOM 22746 C CG . ARG L 1 245 ? 78.232 27.501 79.861 1.00 93.58 ? 245 ARG L CG 1 +ATOM 22747 C CD . ARG L 1 245 ? 78.524 26.735 81.093 1.00 93.85 ? 245 ARG L CD 1 +ATOM 22748 N NE . ARG L 1 245 ? 78.244 25.328 80.977 1.00 104.77 ? 245 ARG L NE 1 +ATOM 22749 C CZ . ARG L 1 245 ? 78.303 24.472 81.988 1.00 126.15 ? 245 ARG L CZ 1 +ATOM 22750 N NH1 . ARG L 1 245 ? 78.464 24.900 83.235 1.00 142.36 ? 245 ARG L NH1 1 +ATOM 22751 N NH2 . ARG L 1 245 ? 78.119 23.192 81.761 1.00 123.04 ? 245 ARG L NH2 1 +ATOM 22752 N N . GLN L 1 246 ? 79.269 32.078 79.149 1.00 64.44 ? 246 GLN L N 1 +ATOM 22753 C CA . GLN L 1 246 ? 79.072 33.494 79.424 1.00 74.57 ? 246 GLN L CA 1 +ATOM 22754 C C . GLN L 1 246 ? 79.508 34.347 78.241 1.00 71.56 ? 246 GLN L C 1 +ATOM 22755 O O . GLN L 1 246 ? 79.733 35.549 78.381 1.00 58.49 ? 246 GLN L O 1 +ATOM 22756 C CB . GLN L 1 246 ? 79.842 33.926 80.673 1.00 76.98 ? 246 GLN L CB 1 +ATOM 22757 C CG . GLN L 1 246 ? 79.278 33.403 81.983 1.00 78.81 ? 246 GLN L CG 1 +ATOM 22758 C CD . GLN L 1 246 ? 79.615 31.957 82.227 1.00 91.72 ? 246 GLN L CD 1 +ATOM 22759 O OE1 . GLN L 1 246 ? 80.724 31.522 81.975 1.00 97.64 ? 246 GLN L OE1 1 +ATOM 22760 N NE2 . GLN L 1 246 ? 78.623 31.184 82.662 1.00 121.90 ? 246 GLN L NE2 1 +ATOM 22761 N N . ASN L 1 247 ? 79.509 33.746 77.060 1.00 91.62 ? 247 ASN L N 1 +ATOM 22762 C CA . ASN L 1 247 ? 79.602 34.474 75.788 1.00 105.72 ? 247 ASN L CA 1 +ATOM 22763 C C . ASN L 1 247 ? 78.762 35.750 75.758 1.00 95.48 ? 247 ASN L C 1 +ATOM 22764 O O . ASN L 1 247 ? 77.604 35.751 76.213 1.00 118.61 ? 247 ASN L O 1 +ATOM 22765 C CB . ASN L 1 247 ? 79.140 33.558 74.646 1.00 108.30 ? 247 ASN L CB 1 +ATOM 22766 C CG . ASN L 1 247 ? 79.783 33.901 73.334 1.00 100.13 ? 247 ASN L CG 1 +ATOM 22767 O OD1 . ASN L 1 247 ? 79.141 34.435 72.439 1.00 83.65 ? 247 ASN L OD1 1 +ATOM 22768 N ND2 . ASN L 1 247 ? 81.073 33.615 73.219 1.00 110.10 ? 247 ASN L ND2 1 +ATOM 22769 N N . ASP L 1 248 ? 79.339 36.828 75.230 1.00 83.72 ? 248 ASP L N 1 +ATOM 22770 C CA . ASP L 1 248 ? 78.673 38.145 75.214 1.00 95.96 ? 248 ASP L CA 1 +ATOM 22771 C C . ASP L 1 248 ? 77.273 38.039 74.596 1.00 93.12 ? 248 ASP L C 1 +ATOM 22772 O O . ASP L 1 248 ? 76.298 38.606 75.104 1.00 94.37 ? 248 ASP L O 1 +ATOM 22773 C CB . ASP L 1 248 ? 79.500 39.161 74.408 1.00 98.32 ? 248 ASP L CB 1 +ATOM 22774 C CG . ASP L 1 248 ? 80.770 39.577 75.111 1.00 102.60 ? 248 ASP L CG 1 +ATOM 22775 O OD1 . ASP L 1 248 ? 80.750 39.751 76.352 1.00 134.96 ? 248 ASP L OD1 1 +ATOM 22776 O OD2 . ASP L 1 248 ? 81.791 39.763 74.419 1.00 99.10 ? 248 ASP L OD2 1 +ATOM 22777 N N . ILE L 1 249 ? 77.199 37.327 73.479 1.00 89.96 ? 249 ILE L N 1 +ATOM 22778 C CA . ILE L 1 249 ? 75.979 37.236 72.696 1.00 91.93 ? 249 ILE L CA 1 +ATOM 22779 C C . ILE L 1 249 ? 74.946 36.441 73.479 1.00 84.56 ? 249 ILE L C 1 +ATOM 22780 O O . ILE L 1 249 ? 73.807 36.875 73.647 1.00 93.23 ? 249 ILE L O 1 +ATOM 22781 C CB . ILE L 1 249 ? 76.259 36.576 71.325 1.00 96.03 ? 249 ILE L CB 1 +ATOM 22782 C CG1 . ILE L 1 249 ? 77.219 37.449 70.490 1.00 107.89 ? 249 ILE L CG1 1 +ATOM 22783 C CG2 . ILE L 1 249 ? 74.968 36.378 70.562 1.00 85.27 ? 249 ILE L CG2 1 +ATOM 22784 C CD1 . ILE L 1 249 ? 77.938 36.705 69.381 1.00 107.21 ? 249 ILE L CD1 1 +ATOM 22785 N N . LEU L 1 250 ? 75.372 35.296 73.997 1.00 89.02 ? 250 LEU L N 1 +ATOM 22786 C CA . LEU L 1 250 ? 74.475 34.396 74.727 1.00 83.32 ? 250 LEU L CA 1 +ATOM 22787 C C . LEU L 1 250 ? 73.864 35.055 75.959 1.00 81.09 ? 250 LEU L C 1 +ATOM 22788 O O . LEU L 1 250 ? 72.696 34.820 76.277 1.00 83.90 ? 250 LEU L O 1 +ATOM 22789 C CB . LEU L 1 250 ? 75.212 33.111 75.123 1.00 72.14 ? 250 LEU L CB 1 +ATOM 22790 C CG . LEU L 1 250 ? 75.336 32.072 74.006 1.00 71.68 ? 250 LEU L CG 1 +ATOM 22791 C CD1 . LEU L 1 250 ? 76.315 30.962 74.365 1.00 63.37 ? 250 LEU L CD1 1 +ATOM 22792 C CD2 . LEU L 1 250 ? 73.965 31.480 73.679 1.00 81.77 ? 250 LEU L CD2 1 +ATOM 22793 N N . VAL L 1 251 ? 74.654 35.874 76.646 1.00 84.09 ? 251 VAL L N 1 +ATOM 22794 C CA . VAL L 1 251 ? 74.172 36.562 77.854 1.00 91.68 ? 251 VAL L CA 1 +ATOM 22795 C C . VAL L 1 251 ? 73.303 37.750 77.476 1.00 91.85 ? 251 VAL L C 1 +ATOM 22796 O O . VAL L 1 251 ? 72.471 38.205 78.263 1.00 121.57 ? 251 VAL L O 1 +ATOM 22797 C CB . VAL L 1 251 ? 75.332 37.013 78.788 1.00 91.47 ? 251 VAL L CB 1 +ATOM 22798 C CG1 . VAL L 1 251 ? 76.231 35.818 79.153 1.00 116.23 ? 251 VAL L CG1 1 +ATOM 22799 C CG2 . VAL L 1 251 ? 76.159 38.125 78.164 1.00 85.49 ? 251 VAL L CG2 1 +ATOM 22800 N N . LYS L 1 252 ? 73.521 38.274 76.274 1.00 87.53 ? 252 LYS L N 1 +ATOM 22801 C CA . LYS L 1 252 ? 72.721 39.395 75.773 1.00 76.28 ? 252 LYS L CA 1 +ATOM 22802 C C . LYS L 1 252 ? 71.290 38.925 75.499 1.00 66.38 ? 252 LYS L C 1 +ATOM 22803 O O . LYS L 1 252 ? 70.323 39.569 75.910 1.00 73.43 ? 252 LYS L O 1 +ATOM 22804 C CB . LYS L 1 252 ? 73.383 39.965 74.516 1.00 81.92 ? 252 LYS L CB 1 +ATOM 22805 C CG . LYS L 1 252 ? 72.643 41.105 73.852 1.00 96.03 ? 252 LYS L CG 1 +ATOM 22806 C CD . LYS L 1 252 ? 73.376 41.555 72.590 1.00 104.40 ? 252 LYS L CD 1 +ATOM 22807 C CE . LYS L 1 252 ? 72.426 41.709 71.409 1.00 112.15 ? 252 LYS L CE 1 +ATOM 22808 N NZ . LYS L 1 252 ? 73.140 41.894 70.118 1.00 109.26 ? 252 LYS L NZ 1 +ATOM 22809 N N . TYR L 1 253 ? 71.163 37.766 74.859 1.00 73.38 ? 253 TYR L N 1 +ATOM 22810 C CA . TYR L 1 253 ? 69.842 37.208 74.496 1.00 81.21 ? 253 TYR L CA 1 +ATOM 22811 C C . TYR L 1 253 ? 69.205 36.606 75.719 1.00 73.38 ? 253 TYR L C 1 +ATOM 22812 O O . TYR L 1 253 ? 67.984 36.573 75.844 1.00 63.68 ? 253 TYR L O 1 +ATOM 22813 C CB . TYR L 1 253 ? 69.938 36.174 73.344 1.00 92.21 ? 253 TYR L CB 1 +ATOM 22814 C CG . TYR L 1 253 ? 70.152 36.825 71.997 1.00 98.32 ? 253 TYR L CG 1 +ATOM 22815 C CD1 . TYR L 1 253 ? 71.454 37.130 71.584 1.00 129.48 ? 253 TYR L CD1 1 +ATOM 22816 C CD2 . TYR L 1 253 ? 69.090 37.231 71.186 1.00 68.64 ? 253 TYR L CD2 1 +ATOM 22817 C CE1 . TYR L 1 253 ? 71.709 37.809 70.409 1.00 129.51 ? 253 TYR L CE1 1 +ATOM 22818 C CE2 . TYR L 1 253 ? 69.349 37.901 70.000 1.00 83.04 ? 253 TYR L CE2 1 +ATOM 22819 C CZ . TYR L 1 253 ? 70.652 38.208 69.624 1.00 114.76 ? 253 TYR L CZ 1 +ATOM 22820 O OH . TYR L 1 253 ? 70.939 38.985 68.495 1.00 139.70 ? 253 TYR L OH 1 +ATOM 22821 N N . ARG L 1 254 ? 70.013 36.128 76.688 1.00 88.02 ? 254 ARG L N 1 +ATOM 22822 C CA . ARG L 1 254 ? 69.545 35.604 77.907 1.00 96.99 ? 254 ARG L CA 1 +ATOM 22823 C C . ARG L 1 254 ? 68.955 36.771 78.723 1.00 82.21 ? 254 ARG L C 1 +ATOM 22824 O O . ARG L 1 254 ? 67.986 36.517 79.442 1.00 85.55 ? 254 ARG L O 1 +ATOM 22825 C CB . ARG L 1 254 ? 70.815 35.141 78.622 1.00 96.89 ? 254 ARG L CB 1 +ATOM 22826 C CG . ARG L 1 254 ? 70.751 35.254 80.137 1.00 84.82 ? 254 ARG L CG 1 +ATOM 22827 C CD . ARG L 1 254 ? 70.052 34.052 80.751 1.00 74.12 ? 254 ARG L CD 1 +ATOM 22828 N NE . ARG L 1 254 ? 69.379 33.237 79.744 1.00 70.43 ? 254 ARG L NE 1 +ATOM 22829 C CZ . ARG L 1 254 ? 69.535 31.923 79.619 1.00 68.53 ? 254 ARG L CZ 1 +ATOM 22830 N NH1 . ARG L 1 254 ? 70.345 31.269 80.441 1.00 62.72 ? 254 ARG L NH1 1 +ATOM 22831 N NH2 . ARG L 1 254 ? 68.882 31.262 78.673 1.00 91.33 ? 254 ARG L NH2 1 +ATOM 22832 N N . HIS L 1 255 ? 69.515 37.930 78.560 1.00 79.22 ? 255 HIS L N 1 +ATOM 22833 C CA . HIS L 1 255 ? 69.025 39.130 79.222 1.00 80.29 ? 255 HIS L CA 1 +ATOM 22834 C C . HIS L 1 255 ? 67.717 39.632 78.619 1.00 81.65 ? 255 HIS L C 1 +ATOM 22835 O O . HIS L 1 255 ? 66.864 40.139 79.338 1.00 89.27 ? 255 HIS L O 1 +ATOM 22836 C CB . HIS L 1 255 ? 70.094 40.237 79.230 1.00 87.93 ? 255 HIS L CB 1 +ATOM 22837 C CG . HIS L 1 255 ? 70.714 40.462 80.585 1.00 122.18 ? 255 HIS L CG 1 +ATOM 22838 N ND1 . HIS L 1 255 ? 70.152 41.307 81.520 1.00 151.92 ? 255 HIS L ND1 1 +ATOM 22839 C CD2 . HIS L 1 255 ? 71.777 39.882 81.203 1.00 138.25 ? 255 HIS L CD2 1 +ATOM 22840 C CE1 . HIS L 1 255 ? 70.847 41.261 82.643 1.00 144.40 ? 255 HIS L CE1 1 +ATOM 22841 N NE2 . HIS L 1 255 ? 71.845 40.412 82.474 1.00 159.65 ? 255 HIS L NE2 1 +ATOM 22842 N N . MET L 1 256 ? 67.533 39.446 77.316 1.00 99.67 ? 256 MET L N 1 +ATOM 22843 C CA . MET L 1 256 ? 66.295 39.889 76.664 1.00 99.21 ? 256 MET L CA 1 +ATOM 22844 C C . MET L 1 256 ? 65.094 39.026 77.072 1.00 89.48 ? 256 MET L C 1 +ATOM 22845 O O . MET L 1 256 ? 63.954 39.508 77.076 1.00 96.74 ? 256 MET L O 1 +ATOM 22846 C CB . MET L 1 256 ? 66.447 39.899 75.137 1.00 103.31 ? 256 MET L CB 1 +ATOM 22847 C CG . MET L 1 256 ? 67.642 40.697 74.630 1.00 113.02 ? 256 MET L CG 1 +ATOM 22848 S SD . MET L 1 256 ? 67.572 41.171 72.880 1.00 104.10 ? 256 MET L SD 1 +ATOM 22849 C CE . MET L 1 256 ? 66.248 42.400 72.951 1.00 105.42 ? 256 MET L CE 1 +ATOM 22850 N N . SER L 1 257 ? 65.354 37.783 77.470 1.00 80.39 ? 257 SER L N 1 +ATOM 22851 C CA . SER L 1 257 ? 64.289 36.894 77.948 1.00 88.18 ? 257 SER L CA 1 +ATOM 22852 C C . SER L 1 257 ? 63.760 37.321 79.313 1.00 110.51 ? 257 SER L C 1 +ATOM 22853 O O . SER L 1 257 ? 62.776 38.044 79.437 1.00 85.05 ? 257 SER L O 1 +ATOM 22854 C CB . SER L 1 257 ? 64.811 35.465 78.060 1.00 87.58 ? 257 SER L CB 1 +ATOM 22855 O OG . SER L 1 257 ? 65.534 35.110 76.922 1.00 103.86 ? 257 SER L OG 1 +ATOM 22856 N N . LEU M 1 2 ? 75.412 56.180 48.116 1.00 147.49 ? 2 LEU M N 1 +ATOM 22857 C CA . LEU M 1 2 ? 74.033 56.348 48.686 1.00 156.49 ? 2 LEU M CA 1 +ATOM 22858 C C . LEU M 1 2 ? 72.954 56.119 47.595 1.00 137.32 ? 2 LEU M C 1 +ATOM 22859 O O . LEU M 1 2 ? 72.256 57.062 47.147 1.00 71.57 ? 2 LEU M O 1 +ATOM 22860 C CB . LEU M 1 2 ? 73.880 57.721 49.366 1.00 165.16 ? 2 LEU M CB 1 +ATOM 22861 C CG . LEU M 1 2 ? 74.793 58.073 50.569 1.00 130.74 ? 2 LEU M CG 1 +ATOM 22862 C CD1 . LEU M 1 2 ? 74.476 59.492 51.043 1.00 109.89 ? 2 LEU M CD1 1 +ATOM 22863 C CD2 . LEU M 1 2 ? 74.714 57.085 51.739 1.00 109.67 ? 2 LEU M CD2 1 +ATOM 22864 N N . THR M 1 3 ? 72.949 54.871 47.113 1.00 141.21 ? 3 THR M N 1 +ATOM 22865 C CA . THR M 1 3 ? 71.867 54.268 46.341 1.00 148.62 ? 3 THR M CA 1 +ATOM 22866 C C . THR M 1 3 ? 71.674 52.773 46.711 1.00 157.55 ? 3 THR M C 1 +ATOM 22867 O O . THR M 1 3 ? 70.778 52.102 46.187 1.00 172.63 ? 3 THR M O 1 +ATOM 22868 C CB . THR M 1 3 ? 72.136 54.332 44.822 1.00 140.23 ? 3 THR M CB 1 +ATOM 22869 O OG1 . THR M 1 3 ? 73.240 53.465 44.487 1.00 119.75 ? 3 THR M OG1 1 +ATOM 22870 C CG2 . THR M 1 3 ? 72.410 55.773 44.363 1.00 139.50 ? 3 THR M CG2 1 +ATOM 22871 N N . ALA M 1 4 ? 72.560 52.237 47.544 1.00 141.00 ? 4 ALA M N 1 +ATOM 22872 C CA . ALA M 1 4 ? 72.376 50.902 48.135 1.00 123.06 ? 4 ALA M CA 1 +ATOM 22873 C C . ALA M 1 4 ? 71.341 50.982 49.286 1.00 115.77 ? 4 ALA M C 1 +ATOM 22874 O O . ALA M 1 4 ? 70.733 52.032 49.493 1.00 108.48 ? 4 ALA M O 1 +ATOM 22875 C CB . ALA M 1 4 ? 73.726 50.342 48.592 1.00 111.05 ? 4 ALA M CB 1 +ATOM 22876 N N . PRO M 1 5 ? 71.072 49.865 49.994 1.00 119.47 ? 5 PRO M N 1 +ATOM 22877 C CA . PRO M 1 5 ? 69.909 49.992 50.868 1.00 111.85 ? 5 PRO M CA 1 +ATOM 22878 C C . PRO M 1 5 ? 70.174 50.791 52.161 1.00 139.47 ? 5 PRO M C 1 +ATOM 22879 O O . PRO M 1 5 ? 71.328 51.133 52.476 1.00 192.07 ? 5 PRO M O 1 +ATOM 22880 C CB . PRO M 1 5 ? 69.572 48.543 51.201 1.00 109.92 ? 5 PRO M CB 1 +ATOM 22881 C CG . PRO M 1 5 ? 70.879 47.806 51.115 1.00 129.64 ? 5 PRO M CG 1 +ATOM 22882 C CD . PRO M 1 5 ? 71.826 48.620 50.264 1.00 133.07 ? 5 PRO M CD 1 +ATOM 22883 N N . PRO M 1 6 ? 69.102 51.141 52.887 1.00 125.41 ? 6 PRO M N 1 +ATOM 22884 C CA . PRO M 1 6 ? 69.225 51.713 54.233 1.00 114.42 ? 6 PRO M CA 1 +ATOM 22885 C C . PRO M 1 6 ? 69.518 50.649 55.282 1.00 107.02 ? 6 PRO M C 1 +ATOM 22886 O O . PRO M 1 6 ? 69.126 49.494 55.097 1.00 97.34 ? 6 PRO M O 1 +ATOM 22887 C CB . PRO M 1 6 ? 67.853 52.375 54.478 1.00 114.14 ? 6 PRO M CB 1 +ATOM 22888 C CG . PRO M 1 6 ? 66.927 51.835 53.460 1.00 99.95 ? 6 PRO M CG 1 +ATOM 22889 C CD . PRO M 1 6 ? 67.734 51.221 52.347 1.00 123.66 ? 6 PRO M CD 1 +ATOM 22890 N N . LYS M 1 7 ? 70.161 51.044 56.383 1.00 103.91 ? 7 LYS M N 1 +ATOM 22891 C CA . LYS M 1 7 ? 70.527 50.089 57.433 1.00 109.80 ? 7 LYS M CA 1 +ATOM 22892 C C . LYS M 1 7 ? 69.506 50.037 58.565 1.00 83.47 ? 7 LYS M C 1 +ATOM 22893 O O . LYS M 1 7 ? 68.620 50.907 58.633 1.00 64.46 ? 7 LYS M O 1 +ATOM 22894 C CB . LYS M 1 7 ? 71.919 50.391 57.993 1.00 118.64 ? 7 LYS M CB 1 +ATOM 22895 C CG . LYS M 1 7 ? 73.052 50.157 57.014 1.00 147.15 ? 7 LYS M CG 1 +ATOM 22896 C CD . LYS M 1 7 ? 73.633 51.449 56.441 1.00 133.18 ? 7 LYS M CD 1 +ATOM 22897 C CE . LYS M 1 7 ? 74.951 51.178 55.731 1.00 139.90 ? 7 LYS M CE 1 +ATOM 22898 N NZ . LYS M 1 7 ? 75.203 52.142 54.626 1.00 131.04 ? 7 LYS M NZ 1 +ATOM 22899 N N . GLU M 1 8 ? 69.628 49.000 59.407 1.00 74.60 ? 8 GLU M N 1 +ATOM 22900 C CA . GLU M 1 8 ? 68.551 48.598 60.339 1.00 80.19 ? 8 GLU M CA 1 +ATOM 22901 C C . GLU M 1 8 ? 68.325 49.639 61.451 1.00 67.60 ? 8 GLU M C 1 +ATOM 22902 O O . GLU M 1 8 ? 69.225 50.055 62.174 1.00 52.88 ? 8 GLU M O 1 +ATOM 22903 C CB . GLU M 1 8 ? 68.668 47.112 60.840 1.00 95.94 ? 8 GLU M CB 1 +ATOM 22904 C CG . GLU M 1 8 ? 68.620 46.011 59.699 1.00 144.37 ? 8 GLU M CG 1 +ATOM 22905 C CD . GLU M 1 8 ? 67.176 45.869 59.054 1.00 154.23 ? 8 GLU M CD 1 +ATOM 22906 O OE1 . GLU M 1 8 ? 66.757 46.878 58.460 1.00 166.34 ? 8 GLU M OE1 1 +ATOM 22907 O OE2 . GLU M 1 8 ? 66.427 44.816 59.033 1.00 87.14 ? 8 GLU M OE2 1 +ATOM 22908 N N . ALA M 1 9 ? 67.123 50.190 61.455 1.00 75.10 ? 9 ALA M N 1 +ATOM 22909 C CA . ALA M 1 9 ? 66.701 51.124 62.481 1.00 73.63 ? 9 ALA M CA 1 +ATOM 22910 C C . ALA M 1 9 ? 65.938 50.334 63.540 1.00 66.26 ? 9 ALA M C 1 +ATOM 22911 O O . ALA M 1 9 ? 64.840 49.842 63.268 1.00 58.49 ? 9 ALA M O 1 +ATOM 22912 C CB . ALA M 1 9 ? 65.814 52.212 61.869 1.00 79.68 ? 9 ALA M CB 1 +ATOM 22913 N N . ALA M 1 10 ? 66.494 50.302 64.754 1.00 56.13 ? 10 ALA M N 1 +ATOM 22914 C CA . ALA M 1 10 ? 65.954 49.559 65.900 1.00 55.56 ? 10 ALA M CA 1 +ATOM 22915 C C . ALA M 1 10 ? 66.413 48.130 65.836 1.00 66.68 ? 10 ALA M C 1 +ATOM 22916 O O . ALA M 1 10 ? 66.831 47.638 64.782 1.00 71.78 ? 10 ALA M O 1 +ATOM 22917 C CB . ALA M 1 10 ? 64.430 49.637 65.986 1.00 57.89 ? 10 ALA M CB 1 +ATOM 22918 N N . ARG M 1 11 ? 66.370 47.466 66.980 1.00 82.58 ? 11 ARG M N 1 +ATOM 22919 C CA . ARG M 1 11 ? 66.828 46.075 67.086 1.00 111.08 ? 11 ARG M CA 1 +ATOM 22920 C C . ARG M 1 11 ? 65.618 45.136 67.078 1.00 94.26 ? 11 ARG M C 1 +ATOM 22921 O O . ARG M 1 11 ? 64.562 45.514 67.550 1.00 87.27 ? 11 ARG M O 1 +ATOM 22922 C CB . ARG M 1 11 ? 67.638 45.871 68.391 1.00 144.40 ? 11 ARG M CB 1 +ATOM 22923 C CG . ARG M 1 11 ? 66.832 46.023 69.676 1.00 161.72 ? 11 ARG M CG 1 +ATOM 22924 C CD . ARG M 1 11 ? 67.701 46.442 70.856 1.00 169.49 ? 11 ARG M CD 1 +ATOM 22925 N NE . ARG M 1 11 ? 67.319 47.755 71.371 1.00 187.36 ? 11 ARG M NE 1 +ATOM 22926 C CZ . ARG M 1 11 ? 67.877 48.326 72.435 1.00 192.17 ? 11 ARG M CZ 1 +ATOM 22927 N NH1 . ARG M 1 11 ? 68.849 47.707 73.090 1.00 183.31 ? 11 ARG M NH1 1 +ATOM 22928 N NH2 . ARG M 1 11 ? 67.479 49.527 72.836 1.00 201.78 ? 11 ARG M NH2 1 +ATOM 22929 N N . PRO M 1 12 ? 65.787 43.892 66.590 1.00 90.25 ? 12 PRO M N 1 +ATOM 22930 C CA . PRO M 1 12 ? 64.790 42.899 66.925 1.00 91.98 ? 12 PRO M CA 1 +ATOM 22931 C C . PRO M 1 12 ? 64.734 42.655 68.433 1.00 103.89 ? 12 PRO M C 1 +ATOM 22932 O O . PRO M 1 12 ? 65.684 42.145 69.036 1.00 99.81 ? 12 PRO M O 1 +ATOM 22933 C CB . PRO M 1 12 ? 65.269 41.642 66.185 1.00 94.89 ? 12 PRO M CB 1 +ATOM 22934 C CG . PRO M 1 12 ? 66.354 42.093 65.262 1.00 89.15 ? 12 PRO M CG 1 +ATOM 22935 C CD . PRO M 1 12 ? 66.946 43.287 65.911 1.00 93.53 ? 12 PRO M CD 1 +ATOM 22936 N N . THR M 1 13 ? 63.610 43.023 69.034 1.00 104.15 ? 13 THR M N 1 +ATOM 22937 C CA . THR M 1 13 ? 63.290 42.610 70.388 1.00 107.61 ? 13 THR M CA 1 +ATOM 22938 C C . THR M 1 13 ? 62.387 41.389 70.387 1.00 95.33 ? 13 THR M C 1 +ATOM 22939 O O . THR M 1 13 ? 61.768 41.046 69.382 1.00 88.25 ? 13 THR M O 1 +ATOM 22940 C CB . THR M 1 13 ? 62.544 43.720 71.126 1.00 108.60 ? 13 THR M CB 1 +ATOM 22941 O OG1 . THR M 1 13 ? 62.467 43.397 72.522 1.00 205.02 ? 13 THR M OG1 1 +ATOM 22942 C CG2 . THR M 1 13 ? 61.129 43.961 70.526 1.00 83.97 ? 13 THR M CG2 1 +ATOM 22943 N N . LEU M 1 14 ? 62.312 40.695 71.509 1.00 79.97 ? 14 LEU M N 1 +ATOM 22944 C CA . LEU M 1 14 ? 61.314 39.661 71.587 1.00 79.52 ? 14 LEU M CA 1 +ATOM 22945 C C . LEU M 1 14 ? 59.970 40.309 71.695 1.00 65.88 ? 14 LEU M C 1 +ATOM 22946 O O . LEU M 1 14 ? 59.934 41.408 72.195 1.00 52.80 ? 14 LEU M O 1 +ATOM 22947 C CB . LEU M 1 14 ? 61.600 38.843 72.813 1.00 69.32 ? 14 LEU M CB 1 +ATOM 22948 C CG . LEU M 1 14 ? 62.802 37.923 72.829 1.00 80.32 ? 14 LEU M CG 1 +ATOM 22949 C CD1 . LEU M 1 14 ? 63.318 37.785 74.248 1.00 76.17 ? 14 LEU M CD1 1 +ATOM 22950 C CD2 . LEU M 1 14 ? 62.347 36.577 72.276 1.00 103.75 ? 14 LEU M CD2 1 +ATOM 22951 N N . MET M 1 15 ? 58.883 39.603 71.384 1.00 74.74 ? 15 MET M N 1 +ATOM 22952 C CA . MET M 1 15 ? 57.612 40.292 71.160 1.00 90.42 ? 15 MET M CA 1 +ATOM 22953 C C . MET M 1 15 ? 57.022 40.933 72.446 1.00 85.52 ? 15 MET M C 1 +ATOM 22954 O O . MET M 1 15 ? 56.773 40.247 73.440 1.00 119.48 ? 15 MET M O 1 +ATOM 22955 C CB . MET M 1 15 ? 56.581 39.366 70.501 1.00 99.49 ? 15 MET M CB 1 +ATOM 22956 C CG . MET M 1 15 ? 55.658 40.134 69.584 1.00 113.57 ? 15 MET M CG 1 +ATOM 22957 S SD . MET M 1 15 ? 53.922 39.755 69.488 1.00 124.62 ? 15 MET M SD 1 +ATOM 22958 C CE . MET M 1 15 ? 53.551 38.683 70.868 1.00 93.27 ? 15 MET M CE 1 +ATOM 22959 N N . PRO M 1 16 ? 56.818 42.248 72.428 1.00 71.92 ? 16 PRO M N 1 +ATOM 22960 C CA . PRO M 1 16 ? 56.450 43.044 73.583 1.00 75.83 ? 16 PRO M CA 1 +ATOM 22961 C C . PRO M 1 16 ? 55.073 42.708 74.158 1.00 86.01 ? 16 PRO M C 1 +ATOM 22962 O O . PRO M 1 16 ? 54.079 43.407 73.887 1.00 130.56 ? 16 PRO M O 1 +ATOM 22963 C CB . PRO M 1 16 ? 56.475 44.473 73.034 1.00 91.64 ? 16 PRO M CB 1 +ATOM 22964 C CG . PRO M 1 16 ? 56.262 44.329 71.565 1.00 99.32 ? 16 PRO M CG 1 +ATOM 22965 C CD . PRO M 1 16 ? 56.976 43.070 71.216 1.00 92.34 ? 16 PRO M CD 1 +ATOM 22966 N N . ARG M 1 17 ? 55.023 41.687 75.004 1.00 73.65 ? 17 ARG M N 1 +ATOM 22967 C CA . ARG M 1 17 ? 53.801 41.345 75.743 1.00 74.96 ? 17 ARG M CA 1 +ATOM 22968 C C . ARG M 1 17 ? 53.770 42.096 77.049 1.00 73.53 ? 17 ARG M C 1 +ATOM 22969 O O . ARG M 1 17 ? 54.820 42.361 77.622 1.00 76.83 ? 17 ARG M O 1 +ATOM 22970 C CB . ARG M 1 17 ? 53.760 39.845 76.007 1.00 86.78 ? 17 ARG M CB 1 +ATOM 22971 C CG . ARG M 1 17 ? 53.123 39.052 74.873 1.00 121.71 ? 17 ARG M CG 1 +ATOM 22972 C CD . ARG M 1 17 ? 53.450 37.564 74.914 1.00 108.30 ? 17 ARG M CD 1 +ATOM 22973 N NE . ARG M 1 17 ? 54.811 37.303 74.443 1.00 132.14 ? 17 ARG M NE 1 +ATOM 22974 C CZ . ARG M 1 17 ? 55.401 36.113 74.493 1.00 154.25 ? 17 ARG M CZ 1 +ATOM 22975 N NH1 . ARG M 1 17 ? 54.732 35.081 74.998 1.00 177.68 ? 17 ARG M NH1 1 +ATOM 22976 N NH2 . ARG M 1 17 ? 56.647 35.952 74.032 1.00 134.64 ? 17 ARG M NH2 1 +ATOM 22977 N N . ALA M 1 18 ? 52.584 42.474 77.524 1.00 93.58 ? 18 ALA M N 1 +ATOM 22978 C CA . ALA M 1 18 ? 52.478 43.290 78.757 1.00 106.27 ? 18 ALA M CA 1 +ATOM 22979 C C . ALA M 1 18 ? 51.817 42.554 79.928 1.00 95.75 ? 18 ALA M C 1 +ATOM 22980 O O . ALA M 1 18 ? 52.360 41.541 80.406 1.00 104.61 ? 18 ALA M O 1 +ATOM 22981 C CB . ALA M 1 18 ? 51.771 44.611 78.487 1.00 112.26 ? 18 ALA M CB 1 +ATOM 22982 N N . GLN M 1 19 ? 50.693 43.077 80.421 1.00 80.40 ? 19 GLN M N 1 +ATOM 22983 C CA . GLN M 1 19 ? 50.227 42.720 81.764 1.00 118.30 ? 19 GLN M CA 1 +ATOM 22984 C C . GLN M 1 19 ? 49.718 41.275 81.831 1.00 118.57 ? 19 GLN M C 1 +ATOM 22985 O O . GLN M 1 19 ? 50.082 40.492 82.734 1.00 106.28 ? 19 GLN M O 1 +ATOM 22986 C CB . GLN M 1 19 ? 49.122 43.682 82.218 1.00 118.89 ? 19 GLN M CB 1 +ATOM 22987 C CG . GLN M 1 19 ? 48.672 43.484 83.665 1.00 117.22 ? 19 GLN M CG 1 +ATOM 22988 C CD . GLN M 1 19 ? 49.836 43.534 84.651 1.00 117.44 ? 19 GLN M CD 1 +ATOM 22989 O OE1 . GLN M 1 19 ? 50.451 44.582 84.848 1.00 126.12 ? 19 GLN M OE1 1 +ATOM 22990 N NE2 . GLN M 1 19 ? 50.133 42.400 85.282 1.00 106.51 ? 19 GLN M NE2 1 +ATOM 22991 N N . SER M 1 20 ? 48.835 40.961 80.896 1.00 109.30 ? 20 SER M N 1 +ATOM 22992 C CA . SER M 1 20 ? 48.339 39.617 80.708 1.00 109.26 ? 20 SER M CA 1 +ATOM 22993 C C . SER M 1 20 ? 49.469 38.589 80.823 1.00 121.70 ? 20 SER M C 1 +ATOM 22994 O O . SER M 1 20 ? 49.350 37.605 81.558 1.00 129.89 ? 20 SER M O 1 +ATOM 22995 C CB . SER M 1 20 ? 47.675 39.535 79.330 1.00 127.42 ? 20 SER M CB 1 +ATOM 22996 O OG . SER M 1 20 ? 46.735 40.590 79.150 1.00 154.31 ? 20 SER M OG 1 +ATOM 22997 N N . TYR M 1 21 ? 50.562 38.829 80.092 1.00 129.35 ? 21 TYR M N 1 +ATOM 22998 C CA . TYR M 1 21 ? 51.751 37.966 80.127 1.00 112.31 ? 21 TYR M CA 1 +ATOM 22999 C C . TYR M 1 21 ? 52.324 37.795 81.535 1.00 124.21 ? 21 TYR M C 1 +ATOM 23000 O O . TYR M 1 21 ? 52.581 36.669 81.988 1.00 125.20 ? 21 TYR M O 1 +ATOM 23001 C CB . TYR M 1 21 ? 52.840 38.529 79.207 1.00 96.38 ? 21 TYR M CB 1 +ATOM 23002 C CG . TYR M 1 21 ? 54.082 37.673 79.153 1.00 103.16 ? 21 TYR M CG 1 +ATOM 23003 C CD1 . TYR M 1 21 ? 54.104 36.485 78.410 1.00 114.20 ? 21 TYR M CD1 1 +ATOM 23004 C CD2 . TYR M 1 21 ? 55.226 38.026 79.844 1.00 99.36 ? 21 TYR M CD2 1 +ATOM 23005 C CE1 . TYR M 1 21 ? 55.225 35.677 78.368 1.00 91.13 ? 21 TYR M CE1 1 +ATOM 23006 C CE2 . TYR M 1 21 ? 56.358 37.229 79.794 1.00 97.77 ? 21 TYR M CE2 1 +ATOM 23007 C CZ . TYR M 1 21 ? 56.343 36.058 79.058 1.00 81.35 ? 21 TYR M CZ 1 +ATOM 23008 O OH . TYR M 1 21 ? 57.443 35.251 78.997 1.00 81.25 ? 21 TYR M OH 1 +ATOM 23009 N N . LYS M 1 22 ? 52.517 38.914 82.226 1.00 126.10 ? 22 LYS M N 1 +ATOM 23010 C CA . LYS M 1 22 ? 53.104 38.903 83.569 1.00 111.92 ? 22 LYS M CA 1 +ATOM 23011 C C . LYS M 1 22 ? 52.266 38.099 84.559 1.00 112.08 ? 22 LYS M C 1 +ATOM 23012 O O . LYS M 1 22 ? 52.800 37.370 85.390 1.00 122.69 ? 22 LYS M O 1 +ATOM 23013 C CB . LYS M 1 22 ? 53.267 40.329 84.081 1.00 104.11 ? 22 LYS M CB 1 +ATOM 23014 C CG . LYS M 1 22 ? 54.545 41.008 83.616 1.00 117.37 ? 22 LYS M CG 1 +ATOM 23015 C CD . LYS M 1 22 ? 55.781 40.981 84.410 1.00 139.94 ? 22 LYS M CD 1 +ATOM 23016 C CE . LYS M 1 22 ? 56.429 42.233 84.024 1.00 145.64 ? 22 LYS M CE 1 +ATOM 23017 N NZ . LYS M 1 22 ? 57.135 43.015 85.054 1.00 163.55 ? 22 LYS M NZ 1 +ATOM 23018 N N . ASP M 1 23 ? 50.947 38.251 84.469 1.00 106.44 ? 23 ASP M N 1 +ATOM 23019 C CA . ASP M 1 23 ? 50.018 37.442 85.263 1.00 102.08 ? 23 ASP M CA 1 +ATOM 23020 C C . ASP M 1 23 ? 50.150 35.963 84.897 1.00 87.49 ? 23 ASP M C 1 +ATOM 23021 O O . ASP M 1 23 ? 50.166 35.091 85.763 1.00 83.35 ? 23 ASP M O 1 +ATOM 23022 C CB . ASP M 1 23 ? 48.565 37.908 85.033 1.00 105.36 ? 23 ASP M CB 1 +ATOM 23023 C CG . ASP M 1 23 ? 48.293 39.267 85.607 1.00 125.35 ? 23 ASP M CG 1 +ATOM 23024 O OD1 . ASP M 1 23 ? 48.829 39.554 86.700 1.00 130.51 ? 23 ASP M OD1 1 +ATOM 23025 O OD2 . ASP M 1 23 ? 47.638 40.083 84.918 1.00 147.41 ? 23 ASP M OD2 1 +ATOM 23026 N N . LEU M 1 24 ? 50.179 35.698 83.594 1.00 93.06 ? 24 LEU M N 1 +ATOM 23027 C CA . LEU M 1 24 ? 50.124 34.336 83.056 1.00 95.81 ? 24 LEU M CA 1 +ATOM 23028 C C . LEU M 1 24 ? 51.361 33.534 83.465 1.00 96.24 ? 24 LEU M C 1 +ATOM 23029 O O . LEU M 1 24 ? 51.277 32.310 83.699 1.00 65.98 ? 24 LEU M O 1 +ATOM 23030 C CB . LEU M 1 24 ? 49.998 34.388 81.523 1.00 93.10 ? 24 LEU M CB 1 +ATOM 23031 C CG . LEU M 1 24 ? 49.940 33.052 80.772 1.00 99.51 ? 24 LEU M CG 1 +ATOM 23032 C CD1 . LEU M 1 24 ? 48.519 32.522 80.690 1.00 101.99 ? 24 LEU M CD1 1 +ATOM 23033 C CD2 . LEU M 1 24 ? 50.515 33.223 79.374 1.00 128.35 ? 24 LEU M CD2 1 +ATOM 23034 N N . THR M 1 25 ? 52.500 34.226 83.545 1.00 93.83 ? 25 THR M N 1 +ATOM 23035 C CA . THR M 1 25 ? 53.770 33.570 83.840 1.00 110.81 ? 25 THR M CA 1 +ATOM 23036 C C . THR M 1 25 ? 53.896 33.250 85.326 1.00 113.38 ? 25 THR M C 1 +ATOM 23037 O O . THR M 1 25 ? 54.256 32.118 85.704 1.00 105.43 ? 25 THR M O 1 +ATOM 23038 C CB . THR M 1 25 ? 54.970 34.435 83.403 1.00 108.12 ? 25 THR M CB 1 +ATOM 23039 O OG1 . THR M 1 25 ? 54.763 35.787 83.813 1.00 101.78 ? 25 THR M OG1 1 +ATOM 23040 C CG2 . THR M 1 25 ? 55.135 34.386 81.891 1.00 100.27 ? 25 THR M CG2 1 +ATOM 23041 N N . HIS M 1 26 ? 53.566 34.232 86.160 1.00 112.95 ? 26 HIS M N 1 +ATOM 23042 C CA . HIS M 1 26 ? 53.678 34.097 87.612 1.00 116.24 ? 26 HIS M CA 1 +ATOM 23043 C C . HIS M 1 26 ? 52.418 33.415 88.216 1.00 116.62 ? 26 HIS M C 1 +ATOM 23044 O O . HIS M 1 26 ? 52.001 33.736 89.319 1.00 95.77 ? 26 HIS M O 1 +ATOM 23045 C CB . HIS M 1 26 ? 53.926 35.479 88.252 1.00 109.16 ? 26 HIS M CB 1 +ATOM 23046 C CG . HIS M 1 26 ? 55.219 36.123 87.833 1.00 110.82 ? 26 HIS M CG 1 +ATOM 23047 N ND1 . HIS M 1 26 ? 55.449 36.578 86.552 1.00 122.64 ? 26 HIS M ND1 1 +ATOM 23048 C CD2 . HIS M 1 26 ? 56.347 36.394 88.531 1.00 117.86 ? 26 HIS M CD2 1 +ATOM 23049 C CE1 . HIS M 1 26 ? 56.664 37.091 86.475 1.00 108.16 ? 26 HIS M CE1 1 +ATOM 23050 N NE2 . HIS M 1 26 ? 57.232 36.987 87.661 1.00 116.57 ? 26 HIS M NE2 1 +ATOM 23051 N N . LEU M 1 27 ? 51.845 32.445 87.504 1.00 118.82 ? 27 LEU M N 1 +ATOM 23052 C CA . LEU M 1 27 ? 50.750 31.630 88.043 1.00 90.98 ? 27 LEU M CA 1 +ATOM 23053 C C . LEU M 1 27 ? 51.286 30.420 88.802 1.00 100.50 ? 27 LEU M C 1 +ATOM 23054 O O . LEU M 1 27 ? 52.218 29.756 88.345 1.00 110.47 ? 27 LEU M O 1 +ATOM 23055 C CB . LEU M 1 27 ? 49.845 31.143 86.921 1.00 88.70 ? 27 LEU M CB 1 +ATOM 23056 C CG . LEU M 1 27 ? 48.734 32.118 86.524 1.00 110.52 ? 27 LEU M CG 1 +ATOM 23057 C CD1 . LEU M 1 27 ? 48.092 31.700 85.209 1.00 129.14 ? 27 LEU M CD1 1 +ATOM 23058 C CD2 . LEU M 1 27 ? 47.683 32.222 87.606 1.00 108.41 ? 27 LEU M CD2 1 +ATOM 23059 N N . PRO M 1 28 ? 50.731 30.147 89.992 1.00 104.43 ? 28 PRO M N 1 +ATOM 23060 C CA . PRO M 1 28 ? 51.176 29.023 90.840 1.00 101.41 ? 28 PRO M CA 1 +ATOM 23061 C C . PRO M 1 28 ? 51.018 27.698 90.133 1.00 94.57 ? 28 PRO M C 1 +ATOM 23062 O O . PRO M 1 28 ? 49.970 27.432 89.575 1.00 113.49 ? 28 PRO M O 1 +ATOM 23063 C CB . PRO M 1 28 ? 50.221 29.078 92.033 1.00 113.52 ? 28 PRO M CB 1 +ATOM 23064 C CG . PRO M 1 28 ? 49.019 29.812 91.535 1.00 113.45 ? 28 PRO M CG 1 +ATOM 23065 C CD . PRO M 1 28 ? 49.550 30.819 90.555 1.00 114.36 ? 28 PRO M CD 1 +ATOM 23066 N N . ALA M 1 29 ? 52.064 26.887 90.122 1.00 104.88 ? 29 ALA M N 1 +ATOM 23067 C CA . ALA M 1 29 ? 52.116 25.725 89.231 1.00 104.88 ? 29 ALA M CA 1 +ATOM 23068 C C . ALA M 1 29 ? 51.177 24.595 89.718 1.00 90.63 ? 29 ALA M C 1 +ATOM 23069 O O . ALA M 1 29 ? 50.965 24.430 90.908 1.00 89.92 ? 29 ALA M O 1 +ATOM 23070 C CB . ALA M 1 29 ? 53.568 25.239 89.070 1.00 95.27 ? 29 ALA M CB 1 +ATOM 23071 N N . PRO M 1 30 ? 50.582 23.847 88.781 1.00 88.67 ? 30 PRO M N 1 +ATOM 23072 C CA . PRO M 1 30 ? 49.803 22.657 89.087 1.00 85.76 ? 30 PRO M CA 1 +ATOM 23073 C C . PRO M 1 30 ? 50.656 21.459 89.557 1.00 77.37 ? 30 PRO M C 1 +ATOM 23074 O O . PRO M 1 30 ? 51.887 21.501 89.456 1.00 62.52 ? 30 PRO M O 1 +ATOM 23075 C CB . PRO M 1 30 ? 49.148 22.336 87.743 1.00 101.76 ? 30 PRO M CB 1 +ATOM 23076 C CG . PRO M 1 30 ? 50.130 22.797 86.721 1.00 117.09 ? 30 PRO M CG 1 +ATOM 23077 C CD . PRO M 1 30 ? 50.840 23.978 87.331 1.00 112.59 ? 30 PRO M CD 1 +ATOM 23078 N N . THR M 1 31 ? 49.993 20.361 89.929 1.00 80.97 ? 31 THR M N 1 +ATOM 23079 C CA . THR M 1 31 ? 50.684 19.129 90.354 1.00 99.68 ? 31 THR M CA 1 +ATOM 23080 C C . THR M 1 31 ? 51.454 18.419 89.233 1.00 90.70 ? 31 THR M C 1 +ATOM 23081 O O . THR M 1 31 ? 52.448 17.748 89.478 1.00 80.68 ? 31 THR M O 1 +ATOM 23082 C CB . THR M 1 31 ? 49.725 18.096 91.003 1.00 123.88 ? 31 THR M CB 1 +ATOM 23083 O OG1 . THR M 1 31 ? 48.624 17.799 90.131 1.00 115.38 ? 31 THR M OG1 1 +ATOM 23084 C CG2 . THR M 1 31 ? 49.191 18.612 92.331 1.00 144.12 ? 31 THR M CG2 1 +ATOM 23085 N N . GLY M 1 32 ? 51.000 18.592 88.001 1.00 101.75 ? 32 GLY M N 1 +ATOM 23086 C CA . GLY M 1 32 ? 51.795 18.250 86.821 1.00 116.85 ? 32 GLY M CA 1 +ATOM 23087 C C . GLY M 1 32 ? 51.318 19.098 85.655 1.00 118.31 ? 32 GLY M C 1 +ATOM 23088 O O . GLY M 1 32 ? 50.162 19.526 85.650 1.00 120.53 ? 32 GLY M O 1 +ATOM 23089 N N . LYS M 1 33 ? 52.163 19.315 84.646 1.00 102.37 ? 33 LYS M N 1 +ATOM 23090 C CA . LYS M 1 33 ? 51.690 19.985 83.437 1.00 85.77 ? 33 LYS M CA 1 +ATOM 23091 C C . LYS M 1 33 ? 50.648 19.138 82.671 1.00 74.51 ? 33 LYS M C 1 +ATOM 23092 O O . LYS M 1 33 ? 50.691 17.903 82.724 1.00 58.79 ? 33 LYS M O 1 +ATOM 23093 C CB . LYS M 1 33 ? 52.844 20.359 82.522 1.00 91.75 ? 33 LYS M CB 1 +ATOM 23094 C CG . LYS M 1 33 ? 53.438 21.719 82.824 1.00 102.35 ? 33 LYS M CG 1 +ATOM 23095 C CD . LYS M 1 33 ? 54.693 21.946 82.001 1.00 131.70 ? 33 LYS M CD 1 +ATOM 23096 C CE . LYS M 1 33 ? 55.623 22.926 82.697 1.00 129.41 ? 33 LYS M CE 1 +ATOM 23097 N NZ . LYS M 1 33 ? 56.928 23.041 81.999 1.00 141.20 ? 33 LYS M NZ 1 +ATOM 23098 N N . ILE M 1 34 ? 49.706 19.802 81.993 1.00 74.11 ? 34 ILE M N 1 +ATOM 23099 C CA . ILE M 1 34 ? 48.652 19.108 81.275 1.00 85.32 ? 34 ILE M CA 1 +ATOM 23100 C C . ILE M 1 34 ? 48.959 19.148 79.764 1.00 108.60 ? 34 ILE M C 1 +ATOM 23101 O O . ILE M 1 34 ? 49.560 20.107 79.261 1.00 105.09 ? 34 ILE M O 1 +ATOM 23102 C CB . ILE M 1 34 ? 47.269 19.689 81.649 1.00 92.71 ? 34 ILE M CB 1 +ATOM 23103 C CG1 . ILE M 1 34 ? 46.963 19.410 83.123 1.00 116.43 ? 34 ILE M CG1 1 +ATOM 23104 C CG2 . ILE M 1 34 ? 46.145 19.073 80.825 1.00 107.69 ? 34 ILE M CG2 1 +ATOM 23105 C CD1 . ILE M 1 34 ? 46.804 20.661 83.958 1.00 134.16 ? 34 ILE M CD1 1 +ATOM 23106 N N . PHE M 1 35 ? 48.680 18.031 79.089 1.00 107.59 ? 35 PHE M N 1 +ATOM 23107 C CA . PHE M 1 35 ? 48.909 17.887 77.661 1.00 107.81 ? 35 PHE M CA 1 +ATOM 23108 C C . PHE M 1 35 ? 47.758 18.512 76.882 1.00 115.21 ? 35 PHE M C 1 +ATOM 23109 O O . PHE M 1 35 ? 46.607 18.095 77.057 1.00 168.31 ? 35 PHE M O 1 +ATOM 23110 C CB . PHE M 1 35 ? 48.956 16.398 77.309 1.00 127.65 ? 35 PHE M CB 1 +ATOM 23111 C CG . PHE M 1 35 ? 50.306 15.768 77.469 1.00 114.75 ? 35 PHE M CG 1 +ATOM 23112 C CD1 . PHE M 1 35 ? 51.443 16.399 77.014 1.00 99.62 ? 35 PHE M CD1 1 +ATOM 23113 C CD2 . PHE M 1 35 ? 50.410 14.485 77.976 1.00 125.21 ? 35 PHE M CD2 1 +ATOM 23114 C CE1 . PHE M 1 35 ? 52.673 15.798 77.144 1.00 112.03 ? 35 PHE M CE1 1 +ATOM 23115 C CE2 . PHE M 1 35 ? 51.635 13.864 78.075 1.00 114.07 ? 35 PHE M CE2 1 +ATOM 23116 C CZ . PHE M 1 35 ? 52.771 14.530 77.670 1.00 112.22 ? 35 PHE M CZ 1 +ATOM 23117 N N . VAL M 1 36 ? 48.060 19.431 75.966 1.00 76.05 ? 36 VAL M N 1 +ATOM 23118 C CA . VAL M 1 36 ? 47.009 20.102 75.238 1.00 56.71 ? 36 VAL M CA 1 +ATOM 23119 C C . VAL M 1 36 ? 47.229 20.152 73.747 1.00 63.86 ? 36 VAL M C 1 +ATOM 23120 O O . VAL M 1 36 ? 48.358 20.125 73.261 1.00 79.88 ? 36 VAL M O 1 +ATOM 23121 C CB . VAL M 1 36 ? 46.876 21.518 75.745 1.00 63.95 ? 36 VAL M CB 1 +ATOM 23122 C CG1 . VAL M 1 36 ? 48.016 22.403 75.247 1.00 62.14 ? 36 VAL M CG1 1 +ATOM 23123 C CG2 . VAL M 1 36 ? 45.528 22.082 75.334 1.00 73.40 ? 36 VAL M CG2 1 +ATOM 23124 N N . SER M 1 37 ? 46.137 20.227 73.003 1.00 78.03 ? 37 SER M N 1 +ATOM 23125 C CA . SER M 1 37 ? 46.192 20.254 71.536 1.00 85.39 ? 37 SER M CA 1 +ATOM 23126 C C . SER M 1 37 ? 45.486 21.492 71.061 1.00 65.74 ? 37 SER M C 1 +ATOM 23127 O O . SER M 1 37 ? 44.370 21.735 71.451 1.00 64.36 ? 37 SER M O 1 +ATOM 23128 C CB . SER M 1 37 ? 45.484 19.028 70.923 1.00 68.88 ? 37 SER M CB 1 +ATOM 23129 O OG . SER M 1 37 ? 46.271 17.851 71.076 1.00 69.57 ? 37 SER M OG 1 +ATOM 23130 N N . VAL M 1 38 ? 46.119 22.250 70.180 1.00 70.79 ? 38 VAL M N 1 +ATOM 23131 C CA . VAL M 1 38 ? 45.397 23.278 69.449 1.00 73.35 ? 38 VAL M CA 1 +ATOM 23132 C C . VAL M 1 38 ? 45.472 23.026 67.943 1.00 80.36 ? 38 VAL M C 1 +ATOM 23133 O O . VAL M 1 38 ? 46.578 23.031 67.386 1.00 97.29 ? 38 VAL M O 1 +ATOM 23134 C CB . VAL M 1 38 ? 45.964 24.683 69.724 1.00 66.06 ? 38 VAL M CB 1 +ATOM 23135 C CG1 . VAL M 1 38 ? 45.191 25.707 68.917 1.00 70.09 ? 38 VAL M CG1 1 +ATOM 23136 C CG2 . VAL M 1 38 ? 45.906 25.025 71.203 1.00 60.94 ? 38 VAL M CG2 1 +ATOM 23137 N N . TYR M 1 39 ? 44.303 22.835 67.302 1.00 80.54 ? 39 TYR M N 1 +ATOM 23138 C CA . TYR M 1 39 ? 44.201 22.527 65.857 1.00 67.21 ? 39 TYR M CA 1 +ATOM 23139 C C . TYR M 1 39 ? 44.056 23.820 65.057 1.00 63.92 ? 39 TYR M C 1 +ATOM 23140 O O . TYR M 1 39 ? 44.899 24.120 64.203 1.00 113.70 ? 39 TYR M O 1 +ATOM 23141 C CB . TYR M 1 39 ? 43.042 21.568 65.571 1.00 58.58 ? 39 TYR M CB 1 +ATOM 23142 C CG . TYR M 1 39 ? 43.393 20.108 65.746 1.00 73.78 ? 39 TYR M CG 1 +ATOM 23143 C CD1 . TYR M 1 39 ? 43.499 19.525 67.012 1.00 72.54 ? 39 TYR M CD1 1 +ATOM 23144 C CD2 . TYR M 1 39 ? 43.697 19.316 64.638 1.00 112.21 ? 39 TYR M CD2 1 +ATOM 23145 C CE1 . TYR M 1 39 ? 43.854 18.199 67.155 1.00 85.75 ? 39 TYR M CE1 1 +ATOM 23146 C CE2 . TYR M 1 39 ? 44.046 17.974 64.757 1.00 116.79 ? 39 TYR M CE2 1 +ATOM 23147 C CZ . TYR M 1 39 ? 44.114 17.415 66.012 1.00 118.94 ? 39 TYR M CZ 1 +ATOM 23148 O OH . TYR M 1 39 ? 44.558 16.104 66.128 1.00 114.88 ? 39 TYR M OH 1 +ATOM 23149 N N . ASN M 1 40 ? 43.140 24.682 65.465 1.00 53.74 ? 40 ASN M N 1 +ATOM 23150 C CA . ASN M 1 40 ? 42.955 25.944 64.774 1.00 59.76 ? 40 ASN M CA 1 +ATOM 23151 C C . ASN M 1 40 ? 42.016 26.920 65.469 1.00 67.08 ? 40 ASN M C 1 +ATOM 23152 O O . ASN M 1 40 ? 40.921 26.547 65.913 1.00 92.86 ? 40 ASN M O 1 +ATOM 23153 C CB . ASN M 1 40 ? 42.395 25.673 63.392 1.00 76.12 ? 40 ASN M CB 1 +ATOM 23154 C CG . ASN M 1 40 ? 42.572 26.855 62.467 1.00 136.12 ? 40 ASN M CG 1 +ATOM 23155 O OD1 . ASN M 1 40 ? 41.597 27.429 61.979 1.00 185.80 ? 40 ASN M OD1 1 +ATOM 23156 N ND2 . ASN M 1 40 ? 43.829 27.206 62.188 1.00 182.62 ? 40 ASN M ND2 1 +ATOM 23157 N N . ILE M 1 41 ? 42.428 28.177 65.560 1.00 85.43 ? 41 ILE M N 1 +ATOM 23158 C CA . ILE M 1 41 ? 41.537 29.261 65.999 1.00 96.21 ? 41 ILE M CA 1 +ATOM 23159 C C . ILE M 1 41 ? 41.353 30.262 64.854 1.00 113.45 ? 41 ILE M C 1 +ATOM 23160 O O . ILE M 1 41 ? 42.322 30.886 64.404 1.00 175.31 ? 41 ILE M O 1 +ATOM 23161 C CB . ILE M 1 41 ? 42.096 30.003 67.240 1.00 77.33 ? 41 ILE M CB 1 +ATOM 23162 C CG1 . ILE M 1 41 ? 41.805 29.233 68.521 1.00 73.51 ? 41 ILE M CG1 1 +ATOM 23163 C CG2 . ILE M 1 41 ? 41.412 31.344 67.377 1.00 81.71 ? 41 ILE M CG2 1 +ATOM 23164 C CD1 . ILE M 1 41 ? 42.585 27.955 68.700 1.00 77.79 ? 41 ILE M CD1 1 +ATOM 23165 N N . GLN M 1 42 ? 40.132 30.388 64.354 1.00 100.87 ? 42 GLN M N 1 +ATOM 23166 C CA . GLN M 1 42 ? 39.893 31.117 63.100 1.00 98.05 ? 42 GLN M CA 1 +ATOM 23167 C C . GLN M 1 42 ? 39.661 32.595 63.334 1.00 81.28 ? 42 GLN M C 1 +ATOM 23168 O O . GLN M 1 42 ? 39.187 32.995 64.388 1.00 86.13 ? 42 GLN M O 1 +ATOM 23169 C CB . GLN M 1 42 ? 38.687 30.539 62.345 1.00 123.98 ? 42 GLN M CB 1 +ATOM 23170 C CG . GLN M 1 42 ? 38.878 29.116 61.845 1.00 162.64 ? 42 GLN M CG 1 +ATOM 23171 C CD . GLN M 1 42 ? 37.872 28.143 62.451 1.00 200.22 ? 42 GLN M CD 1 +ATOM 23172 O OE1 . GLN M 1 42 ? 36.779 27.953 61.916 1.00 211.12 ? 42 GLN M OE1 1 +ATOM 23173 N NE2 . GLN M 1 42 ? 38.227 27.544 63.587 1.00 215.51 ? 42 GLN M NE2 1 +ATOM 23174 N N . ASP M 1 43 ? 39.893 33.378 62.289 1.00 70.31 ? 43 ASP M N 1 +ATOM 23175 C CA . ASP M 1 43 ? 39.454 34.756 62.220 1.00 73.07 ? 43 ASP M CA 1 +ATOM 23176 C C . ASP M 1 43 ? 37.973 34.820 61.839 1.00 84.16 ? 43 ASP M C 1 +ATOM 23177 O O . ASP M 1 43 ? 37.617 35.358 60.787 1.00 86.08 ? 43 ASP M O 1 +ATOM 23178 C CB . ASP M 1 43 ? 40.283 35.523 61.184 1.00 83.60 ? 43 ASP M CB 1 +ATOM 23179 C CG . ASP M 1 43 ? 40.057 37.042 61.242 1.00 101.76 ? 43 ASP M CG 1 +ATOM 23180 O OD1 . ASP M 1 43 ? 40.118 37.618 62.348 1.00 94.23 ? 43 ASP M OD1 1 +ATOM 23181 O OD2 . ASP M 1 43 ? 39.811 37.680 60.190 1.00 125.94 ? 43 ASP M OD2 1 +ATOM 23182 N N . GLU M 1 44 ? 37.100 34.335 62.730 1.00 113.40 ? 44 GLU M N 1 +ATOM 23183 C CA . GLU M 1 44 ? 35.630 34.327 62.508 1.00 118.32 ? 44 GLU M CA 1 +ATOM 23184 C C . GLU M 1 44 ? 35.005 35.752 62.556 1.00 89.68 ? 44 GLU M C 1 +ATOM 23185 O O . GLU M 1 44 ? 33.776 35.904 62.590 1.00 75.17 ? 44 GLU M O 1 +ATOM 23186 C CB . GLU M 1 44 ? 34.925 33.404 63.533 1.00 124.48 ? 44 GLU M CB 1 +ATOM 23187 C CG . GLU M 1 44 ? 34.848 31.920 63.144 1.00 108.94 ? 44 GLU M CG 1 +ATOM 23188 C CD . GLU M 1 44 ? 34.174 31.019 64.206 1.00 126.21 ? 44 GLU M CD 1 +ATOM 23189 O OE1 . GLU M 1 44 ? 33.111 31.389 64.782 1.00 152.08 ? 44 GLU M OE1 1 +ATOM 23190 O OE2 . GLU M 1 44 ? 34.703 29.920 64.483 1.00 95.97 ? 44 GLU M OE2 1 +ATOM 23191 N N . THR M 1 45 ? 35.868 36.772 62.480 1.00 68.13 ? 45 THR M N 1 +ATOM 23192 C CA . THR M 1 45 ? 35.464 38.164 62.643 1.00 68.55 ? 45 THR M CA 1 +ATOM 23193 C C . THR M 1 45 ? 34.661 38.702 61.454 1.00 80.95 ? 45 THR M C 1 +ATOM 23194 O O . THR M 1 45 ? 33.703 39.444 61.650 1.00 75.83 ? 45 THR M O 1 +ATOM 23195 C CB . THR M 1 45 ? 36.665 39.102 63.012 1.00 58.65 ? 45 THR M CB 1 +ATOM 23196 O OG1 . THR M 1 45 ? 36.160 40.342 63.477 1.00 50.30 ? 45 THR M OG1 1 +ATOM 23197 C CG2 . THR M 1 45 ? 37.583 39.370 61.850 1.00 59.03 ? 45 THR M CG2 1 +ATOM 23198 N N . GLY M 1 46 ? 35.089 38.390 60.233 1.00 112.54 ? 46 GLY M N 1 +ATOM 23199 C CA . GLY M 1 46 ? 34.344 38.773 59.023 1.00 117.97 ? 46 GLY M CA 1 +ATOM 23200 C C . GLY M 1 46 ? 34.733 40.142 58.468 1.00 124.51 ? 46 GLY M C 1 +ATOM 23201 O O . GLY M 1 46 ? 33.984 40.808 57.725 1.00 81.65 ? 46 GLY M O 1 +ATOM 23202 N N . GLN M 1 47 ? 35.891 40.615 58.880 1.00 104.98 ? 47 GLN M N 1 +ATOM 23203 C CA . GLN M 1 47 ? 36.127 42.001 58.767 1.00 83.50 ? 47 GLN M CA 1 +ATOM 23204 C C . GLN M 1 47 ? 37.446 42.277 58.094 1.00 71.99 ? 47 GLN M C 1 +ATOM 23205 O O . GLN M 1 47 ? 38.464 41.646 58.346 1.00 46.93 ? 47 GLN M O 1 +ATOM 23206 C CB . GLN M 1 47 ? 36.045 42.635 60.126 1.00 75.95 ? 47 GLN M CB 1 +ATOM 23207 C CG . GLN M 1 47 ? 34.636 42.631 60.677 1.00 106.09 ? 47 GLN M CG 1 +ATOM 23208 C CD . GLN M 1 47 ? 33.611 43.167 59.691 1.00 141.51 ? 47 GLN M CD 1 +ATOM 23209 O OE1 . GLN M 1 47 ? 33.534 44.361 59.453 1.00 144.69 ? 47 GLN M OE1 1 +ATOM 23210 N NE2 . GLN M 1 47 ? 32.779 42.288 59.158 1.00 181.00 ? 47 GLN M NE2 1 +ATOM 23211 N N . PHE M 1 48 ? 37.385 43.260 57.205 1.00 86.27 ? 48 PHE M N 1 +ATOM 23212 C CA . PHE M 1 48 ? 38.535 43.741 56.486 1.00 77.76 ? 48 PHE M CA 1 +ATOM 23213 C C . PHE M 1 48 ? 38.692 45.240 56.701 1.00 84.56 ? 48 PHE M C 1 +ATOM 23214 O O . PHE M 1 48 ? 37.784 45.951 57.154 1.00 81.98 ? 48 PHE M O 1 +ATOM 23215 C CB . PHE M 1 48 ? 38.375 43.461 54.992 1.00 81.39 ? 48 PHE M CB 1 +ATOM 23216 C CG . PHE M 1 48 ? 38.369 42.031 54.669 1.00 72.93 ? 48 PHE M CG 1 +ATOM 23217 C CD1 . PHE M 1 48 ? 37.211 41.293 54.856 1.00 76.99 ? 48 PHE M CD1 1 +ATOM 23218 C CD2 . PHE M 1 48 ? 39.491 41.427 54.202 1.00 61.42 ? 48 PHE M CD2 1 +ATOM 23219 C CE1 . PHE M 1 48 ? 37.188 39.948 54.613 1.00 82.61 ? 48 PHE M CE1 1 +ATOM 23220 C CE2 . PHE M 1 48 ? 39.469 40.087 53.926 1.00 75.55 ? 48 PHE M CE2 1 +ATOM 23221 C CZ . PHE M 1 48 ? 38.325 39.343 54.133 1.00 82.17 ? 48 PHE M CZ 1 +ATOM 23222 N N . LYS M 1 49 ? 39.847 45.724 56.287 1.00 92.76 ? 49 LYS M N 1 +ATOM 23223 C CA . LYS M 1 49 ? 40.171 47.119 56.452 1.00 91.39 ? 49 LYS M CA 1 +ATOM 23224 C C . LYS M 1 49 ? 39.443 47.937 55.393 1.00 91.97 ? 49 LYS M C 1 +ATOM 23225 O O . LYS M 1 49 ? 39.260 47.485 54.267 1.00 87.87 ? 49 LYS M O 1 +ATOM 23226 C CB . LYS M 1 49 ? 41.696 47.321 56.405 1.00 89.01 ? 49 LYS M CB 1 +ATOM 23227 C CG . LYS M 1 49 ? 42.411 46.646 57.576 1.00 92.18 ? 49 LYS M CG 1 +ATOM 23228 C CD . LYS M 1 49 ? 43.884 46.951 57.755 1.00 91.05 ? 49 LYS M CD 1 +ATOM 23229 C CE . LYS M 1 49 ? 44.315 46.325 59.086 1.00 86.56 ? 49 LYS M CE 1 +ATOM 23230 N NZ . LYS M 1 49 ? 45.732 46.562 59.467 1.00 109.12 ? 49 LYS M NZ 1 +ATOM 23231 N N . PRO M 1 50 ? 39.031 49.152 55.766 1.00 108.84 ? 50 PRO M N 1 +ATOM 23232 C CA . PRO M 1 50 ? 38.382 50.071 54.847 1.00 108.56 ? 50 PRO M CA 1 +ATOM 23233 C C . PRO M 1 50 ? 39.365 50.783 53.906 1.00 80.09 ? 50 PRO M C 1 +ATOM 23234 O O . PRO M 1 50 ? 40.596 50.708 54.105 1.00 57.75 ? 50 PRO M O 1 +ATOM 23235 C CB . PRO M 1 50 ? 37.722 51.081 55.789 1.00 120.36 ? 50 PRO M CB 1 +ATOM 23236 C CG . PRO M 1 50 ? 38.591 51.099 57.001 1.00 113.78 ? 50 PRO M CG 1 +ATOM 23237 C CD . PRO M 1 50 ? 39.143 49.709 57.131 1.00 115.41 ? 50 PRO M CD 1 +ATOM 23238 N N . TYR M 1 51 ? 38.816 51.471 52.908 1.00 50.35 ? 51 TYR M N 1 +ATOM 23239 C CA . TYR M 1 51 ? 39.632 52.279 52.056 1.00 49.38 ? 51 TYR M CA 1 +ATOM 23240 C C . TYR M 1 51 ? 40.454 53.187 52.931 1.00 47.45 ? 51 TYR M C 1 +ATOM 23241 O O . TYR M 1 51 ? 39.926 53.772 53.880 1.00 42.75 ? 51 TYR M O 1 +ATOM 23242 C CB . TYR M 1 51 ? 38.768 53.100 51.097 1.00 59.68 ? 51 TYR M CB 1 +ATOM 23243 C CG . TYR M 1 51 ? 39.597 53.717 49.984 1.00 68.63 ? 51 TYR M CG 1 +ATOM 23244 C CD1 . TYR M 1 51 ? 39.858 52.998 48.825 1.00 70.44 ? 51 TYR M CD1 1 +ATOM 23245 C CD2 . TYR M 1 51 ? 40.142 54.998 50.098 1.00 75.71 ? 51 TYR M CD2 1 +ATOM 23246 C CE1 . TYR M 1 51 ? 40.664 53.499 47.824 1.00 79.53 ? 51 TYR M CE1 1 +ATOM 23247 C CE2 . TYR M 1 51 ? 40.931 55.534 49.076 1.00 87.88 ? 51 TYR M CE2 1 +ATOM 23248 C CZ . TYR M 1 51 ? 41.222 54.749 47.958 1.00 98.28 ? 51 TYR M CZ 1 +ATOM 23249 O OH . TYR M 1 51 ? 42.010 55.200 46.912 1.00 101.93 ? 51 TYR M OH 1 +ATOM 23250 N N . PRO M 1 52 ? 41.755 53.357 52.617 1.00 59.80 ? 52 PRO M N 1 +ATOM 23251 C CA . PRO M 1 52 ? 42.501 52.921 51.438 1.00 69.46 ? 52 PRO M CA 1 +ATOM 23252 C C . PRO M 1 52 ? 43.247 51.609 51.534 1.00 79.97 ? 52 PRO M C 1 +ATOM 23253 O O . PRO M 1 52 ? 44.130 51.359 50.703 1.00 70.20 ? 52 PRO M O 1 +ATOM 23254 C CB . PRO M 1 52 ? 43.532 54.032 51.258 1.00 82.52 ? 52 PRO M CB 1 +ATOM 23255 C CG . PRO M 1 52 ? 43.844 54.453 52.657 1.00 88.55 ? 52 PRO M CG 1 +ATOM 23256 C CD . PRO M 1 52 ? 42.553 54.303 53.431 1.00 78.22 ? 52 PRO M CD 1 +ATOM 23257 N N . ALA M 1 53 ? 42.867 50.747 52.473 1.00 89.99 ? 53 ALA M N 1 +ATOM 23258 C CA . ALA M 1 53 ? 43.516 49.443 52.561 1.00 93.10 ? 53 ALA M CA 1 +ATOM 23259 C C . ALA M 1 53 ? 43.147 48.591 51.375 1.00 78.04 ? 53 ALA M C 1 +ATOM 23260 O O . ALA M 1 53 ? 42.162 48.863 50.647 1.00 67.58 ? 53 ALA M O 1 +ATOM 23261 C CB . ALA M 1 53 ? 43.121 48.725 53.823 1.00 116.02 ? 53 ALA M CB 1 +ATOM 23262 N N . SER M 1 54 ? 43.977 47.583 51.123 1.00 66.39 ? 54 SER M N 1 +ATOM 23263 C CA . SER M 1 54 ? 43.591 46.601 50.116 1.00 55.07 ? 54 SER M CA 1 +ATOM 23264 C C . SER M 1 54 ? 42.244 46.014 50.540 1.00 43.41 ? 54 SER M C 1 +ATOM 23265 O O . SER M 1 54 ? 42.018 45.752 51.722 1.00 40.39 ? 54 SER M O 1 +ATOM 23266 C CB . SER M 1 54 ? 44.668 45.511 49.917 1.00 45.04 ? 54 SER M CB 1 +ATOM 23267 O OG . SER M 1 54 ? 44.123 44.317 49.352 1.00 30.01 ? 54 SER M OG 1 +ATOM 23268 N N . ASN M 1 55 ? 41.410 45.752 49.545 1.00 36.21 ? 55 ASN M N 1 +ATOM 23269 C CA . ASN M 1 55 ? 40.193 45.022 49.736 1.00 39.29 ? 55 ASN M CA 1 +ATOM 23270 C C . ASN M 1 55 ? 40.360 43.763 50.589 1.00 43.63 ? 55 ASN M C 1 +ATOM 23271 O O . ASN M 1 55 ? 39.479 43.337 51.330 1.00 35.53 ? 55 ASN M O 1 +ATOM 23272 C CB . ASN M 1 55 ? 39.659 44.622 48.379 1.00 40.96 ? 55 ASN M CB 1 +ATOM 23273 C CG . ASN M 1 55 ? 38.249 44.143 48.459 1.00 67.90 ? 55 ASN M CG 1 +ATOM 23274 O OD1 . ASN M 1 55 ? 37.487 44.497 49.372 1.00 109.68 ? 55 ASN M OD1 1 +ATOM 23275 N ND2 . ASN M 1 55 ? 37.821 43.510 47.404 1.00 96.44 ? 55 ASN M ND2 1 +ATOM 23276 N N . PHE M 1 56 ? 41.538 43.166 50.482 1.00 57.10 ? 56 PHE M N 1 +ATOM 23277 C CA . PHE M 1 56 ? 41.795 41.856 51.055 1.00 54.68 ? 56 PHE M CA 1 +ATOM 23278 C C . PHE M 1 56 ? 42.492 41.919 52.404 1.00 67.36 ? 56 PHE M C 1 +ATOM 23279 O O . PHE M 1 56 ? 42.912 40.881 52.933 1.00 77.59 ? 56 PHE M O 1 +ATOM 23280 C CB . PHE M 1 56 ? 42.685 41.050 50.118 1.00 55.36 ? 56 PHE M CB 1 +ATOM 23281 C CG . PHE M 1 56 ? 42.101 40.849 48.765 1.00 46.36 ? 56 PHE M CG 1 +ATOM 23282 C CD1 . PHE M 1 56 ? 40.897 40.189 48.584 1.00 37.54 ? 56 PHE M CD1 1 +ATOM 23283 C CD2 . PHE M 1 56 ? 42.788 41.293 47.667 1.00 56.26 ? 56 PHE M CD2 1 +ATOM 23284 C CE1 . PHE M 1 56 ? 40.379 39.986 47.328 1.00 39.16 ? 56 PHE M CE1 1 +ATOM 23285 C CE2 . PHE M 1 56 ? 42.294 41.047 46.392 1.00 61.02 ? 56 PHE M CE2 1 +ATOM 23286 C CZ . PHE M 1 56 ? 41.078 40.402 46.223 1.00 44.98 ? 56 PHE M CZ 1 +ATOM 23287 N N . SER M 1 57 ? 42.788 43.120 52.890 1.00 69.28 ? 57 SER M N 1 +ATOM 23288 C CA . SER M 1 57 ? 43.542 43.236 54.145 1.00 71.60 ? 57 SER M CA 1 +ATOM 23289 C C . SER M 1 57 ? 42.564 42.964 55.272 1.00 81.34 ? 57 SER M C 1 +ATOM 23290 O O . SER M 1 57 ? 41.601 43.691 55.467 1.00 70.49 ? 57 SER M O 1 +ATOM 23291 C CB . SER M 1 57 ? 44.208 44.615 54.297 1.00 66.12 ? 57 SER M CB 1 +ATOM 23292 O OG . SER M 1 57 ? 45.354 44.704 53.466 1.00 66.40 ? 57 SER M OG 1 +ATOM 23293 N N . THR M 1 58 ? 42.814 41.888 56.010 1.00 89.82 ? 58 THR M N 1 +ATOM 23294 C CA . THR M 1 58 ? 41.950 41.515 57.110 1.00 65.51 ? 58 THR M CA 1 +ATOM 23295 C C . THR M 1 58 ? 42.143 42.457 58.266 1.00 68.51 ? 58 THR M C 1 +ATOM 23296 O O . THR M 1 58 ? 43.186 43.043 58.479 1.00 40.14 ? 58 THR M O 1 +ATOM 23297 C CB . THR M 1 58 ? 42.288 40.130 57.628 1.00 49.28 ? 58 THR M CB 1 +ATOM 23298 O OG1 . THR M 1 58 ? 43.635 40.101 58.088 1.00 34.66 ? 58 THR M OG1 1 +ATOM 23299 C CG2 . THR M 1 58 ? 42.147 39.163 56.534 1.00 56.42 ? 58 THR M CG2 1 +ATOM 23300 N N . ALA M 1 59 ? 41.104 42.625 59.032 1.00 92.19 ? 59 ALA M N 1 +ATOM 23301 C CA . ALA M 1 59 ? 41.218 43.587 60.097 1.00 99.71 ? 59 ALA M CA 1 +ATOM 23302 C C . ALA M 1 59 ? 42.064 43.019 61.233 1.00 79.74 ? 59 ALA M C 1 +ATOM 23303 O O . ALA M 1 59 ? 42.528 43.746 62.092 1.00 85.86 ? 59 ALA M O 1 +ATOM 23304 C CB . ALA M 1 59 ? 39.837 43.995 60.573 1.00 124.90 ? 59 ALA M CB 1 +ATOM 23305 N N . VAL M 1 60 ? 42.179 41.696 61.271 1.00 71.68 ? 60 VAL M N 1 +ATOM 23306 C CA . VAL M 1 60 ? 42.754 40.983 62.407 1.00 63.94 ? 60 VAL M CA 1 +ATOM 23307 C C . VAL M 1 60 ? 43.749 39.972 61.848 1.00 63.30 ? 60 VAL M C 1 +ATOM 23308 O O . VAL M 1 60 ? 43.470 39.309 60.851 1.00 88.47 ? 60 VAL M O 1 +ATOM 23309 C CB . VAL M 1 60 ? 41.650 40.233 63.193 1.00 65.63 ? 60 VAL M CB 1 +ATOM 23310 C CG1 . VAL M 1 60 ? 42.231 39.457 64.360 1.00 70.05 ? 60 VAL M CG1 1 +ATOM 23311 C CG2 . VAL M 1 60 ? 40.602 41.204 63.689 1.00 85.04 ? 60 VAL M CG2 1 +ATOM 23312 N N . PRO M 1 61 ? 44.912 39.850 62.476 1.00 52.15 ? 61 PRO M N 1 +ATOM 23313 C CA . PRO M 1 61 ? 45.845 38.855 61.995 1.00 54.57 ? 61 PRO M CA 1 +ATOM 23314 C C . PRO M 1 61 ? 45.306 37.441 62.060 1.00 59.21 ? 61 PRO M C 1 +ATOM 23315 O O . PRO M 1 61 ? 44.631 37.062 63.059 1.00 97.99 ? 61 PRO M O 1 +ATOM 23316 C CB . PRO M 1 61 ? 47.060 39.032 62.938 1.00 62.70 ? 61 PRO M CB 1 +ATOM 23317 C CG . PRO M 1 61 ? 46.524 39.691 64.165 1.00 52.51 ? 61 PRO M CG 1 +ATOM 23318 C CD . PRO M 1 61 ? 45.418 40.574 63.657 1.00 54.46 ? 61 PRO M CD 1 +ATOM 23319 N N . GLN M 1 62 ? 45.707 36.632 61.082 1.00 57.33 ? 62 GLN M N 1 +ATOM 23320 C CA . GLN M 1 62 ? 45.254 35.245 60.998 1.00 64.10 ? 62 GLN M CA 1 +ATOM 23321 C C . GLN M 1 62 ? 46.123 34.308 61.798 1.00 61.69 ? 62 GLN M C 1 +ATOM 23322 O O . GLN M 1 62 ? 46.320 33.166 61.410 1.00 53.48 ? 62 GLN M O 1 +ATOM 23323 C CB . GLN M 1 62 ? 45.276 34.786 59.547 1.00 82.04 ? 62 GLN M CB 1 +ATOM 23324 C CG . GLN M 1 62 ? 44.584 35.751 58.601 1.00 106.91 ? 62 GLN M CG 1 +ATOM 23325 C CD . GLN M 1 62 ? 43.134 35.985 58.992 1.00 111.47 ? 62 GLN M CD 1 +ATOM 23326 O OE1 . GLN M 1 62 ? 42.263 35.168 58.708 1.00 101.16 ? 62 GLN M OE1 1 +ATOM 23327 N NE2 . GLN M 1 62 ? 42.874 37.099 59.649 1.00 110.97 ? 62 GLN M NE2 1 +ATOM 23328 N N . SER M 1 63 ? 46.626 34.782 62.941 1.00 77.87 ? 63 SER M N 1 +ATOM 23329 C CA . SER M 1 63 ? 47.749 34.135 63.636 1.00 75.86 ? 63 SER M CA 1 +ATOM 23330 C C . SER M 1 63 ? 47.383 33.752 65.079 1.00 93.81 ? 63 SER M C 1 +ATOM 23331 O O . SER M 1 63 ? 48.218 33.233 65.824 1.00 101.69 ? 63 SER M O 1 +ATOM 23332 C CB . SER M 1 63 ? 48.966 35.065 63.635 1.00 53.71 ? 63 SER M CB 1 +ATOM 23333 O OG . SER M 1 63 ? 48.700 36.249 64.348 1.00 41.33 ? 63 SER M OG 1 +ATOM 23334 N N . ALA M 1 64 ? 46.092 33.838 65.397 1.00 112.93 ? 64 ALA M N 1 +ATOM 23335 C CA . ALA M 1 64 ? 45.598 33.518 66.729 1.00 127.63 ? 64 ALA M CA 1 +ATOM 23336 C C . ALA M 1 64 ? 46.026 32.129 67.274 1.00 158.70 ? 64 ALA M C 1 +ATOM 23337 O O . ALA M 1 64 ? 46.341 31.973 68.467 1.00 164.30 ? 64 ALA M O 1 +ATOM 23338 C CB . ALA M 1 64 ? 44.081 33.644 66.748 1.00 144.19 ? 64 ALA M CB 1 +ATOM 23339 N N . THR M 1 65 ? 45.989 31.118 66.407 1.00 153.76 ? 65 THR M N 1 +ATOM 23340 C CA . THR M 1 65 ? 46.311 29.735 66.775 1.00 119.26 ? 65 THR M CA 1 +ATOM 23341 C C . THR M 1 65 ? 47.669 29.636 67.445 1.00 101.15 ? 65 THR M C 1 +ATOM 23342 O O . THR M 1 65 ? 47.803 29.047 68.518 1.00 102.88 ? 65 THR M O 1 +ATOM 23343 C CB . THR M 1 65 ? 46.365 28.867 65.519 1.00 107.66 ? 65 THR M CB 1 +ATOM 23344 O OG1 . THR M 1 65 ? 45.305 29.263 64.646 1.00 112.10 ? 65 THR M OG1 1 +ATOM 23345 C CG2 . THR M 1 65 ? 46.245 27.390 65.879 1.00 103.42 ? 65 THR M CG2 1 +ATOM 23346 N N . ALA M 1 66 ? 48.665 30.241 66.814 1.00 93.26 ? 66 ALA M N 1 +ATOM 23347 C CA . ALA M 1 66 ? 50.007 30.174 67.325 1.00 88.45 ? 66 ALA M CA 1 +ATOM 23348 C C . ALA M 1 66 ? 50.167 30.984 68.625 1.00 68.31 ? 66 ALA M C 1 +ATOM 23349 O O . ALA M 1 66 ? 50.914 30.569 69.535 1.00 54.24 ? 66 ALA M O 1 +ATOM 23350 C CB . ALA M 1 66 ? 50.975 30.652 66.265 1.00 105.04 ? 66 ALA M CB 1 +ATOM 23351 N N . MET M 1 67 ? 49.455 32.108 68.708 1.00 52.02 ? 67 MET M N 1 +ATOM 23352 C CA . MET M 1 67 ? 49.460 32.917 69.916 1.00 63.07 ? 67 MET M CA 1 +ATOM 23353 C C . MET M 1 67 ? 48.864 32.129 71.085 1.00 62.54 ? 67 MET M C 1 +ATOM 23354 O O . MET M 1 67 ? 49.405 32.165 72.226 1.00 68.28 ? 67 MET M O 1 +ATOM 23355 C CB . MET M 1 67 ? 48.644 34.190 69.731 1.00 84.80 ? 67 MET M CB 1 +ATOM 23356 C CG . MET M 1 67 ? 49.244 35.233 68.792 1.00 75.96 ? 67 MET M CG 1 +ATOM 23357 S SD . MET M 1 67 ? 48.014 36.523 68.388 1.00 93.70 ? 67 MET M SD 1 +ATOM 23358 C CE . MET M 1 67 ? 49.025 37.676 67.469 1.00 92.41 ? 67 MET M CE 1 +ATOM 23359 N N . LEU M 1 68 ? 47.775 31.394 70.817 1.00 45.26 ? 68 LEU M N 1 +ATOM 23360 C CA . LEU M 1 68 ? 47.182 30.584 71.861 1.00 53.27 ? 68 LEU M CA 1 +ATOM 23361 C C . LEU M 1 68 ? 48.144 29.476 72.346 1.00 66.18 ? 68 LEU M C 1 +ATOM 23362 O O . LEU M 1 68 ? 48.264 29.245 73.559 1.00 77.92 ? 68 LEU M O 1 +ATOM 23363 C CB . LEU M 1 68 ? 45.888 29.943 71.419 1.00 52.53 ? 68 LEU M CB 1 +ATOM 23364 C CG . LEU M 1 68 ? 45.318 28.903 72.423 1.00 65.77 ? 68 LEU M CG 1 +ATOM 23365 C CD1 . LEU M 1 68 ? 44.887 29.567 73.737 1.00 62.36 ? 68 LEU M CD1 1 +ATOM 23366 C CD2 . LEU M 1 68 ? 44.158 28.095 71.847 1.00 63.82 ? 68 LEU M CD2 1 +ATOM 23367 N N . VAL M 1 69 ? 48.781 28.775 71.417 1.00 62.73 ? 69 VAL M N 1 +ATOM 23368 C CA . VAL M 1 69 ? 49.698 27.697 71.775 1.00 51.73 ? 69 VAL M CA 1 +ATOM 23369 C C . VAL M 1 69 ? 50.813 28.269 72.593 1.00 52.82 ? 69 VAL M C 1 +ATOM 23370 O O . VAL M 1 69 ? 51.213 27.699 73.631 1.00 77.73 ? 69 VAL M O 1 +ATOM 23371 C CB . VAL M 1 69 ? 50.314 27.026 70.543 1.00 62.02 ? 69 VAL M CB 1 +ATOM 23372 C CG1 . VAL M 1 69 ? 51.401 26.068 70.958 1.00 57.99 ? 69 VAL M CG1 1 +ATOM 23373 C CG2 . VAL M 1 69 ? 49.254 26.272 69.730 1.00 68.16 ? 69 VAL M CG2 1 +ATOM 23374 N N . THR M 1 70 ? 51.318 29.417 72.161 1.00 50.89 ? 70 THR M N 1 +ATOM 23375 C CA . THR M 1 70 ? 52.371 30.103 72.922 1.00 77.72 ? 70 THR M CA 1 +ATOM 23376 C C . THR M 1 70 ? 51.961 30.545 74.352 1.00 57.83 ? 70 THR M C 1 +ATOM 23377 O O . THR M 1 70 ? 52.690 30.283 75.329 1.00 48.90 ? 70 THR M O 1 +ATOM 23378 C CB . THR M 1 70 ? 52.885 31.323 72.156 1.00 95.24 ? 70 THR M CB 1 +ATOM 23379 O OG1 . THR M 1 70 ? 53.279 30.905 70.840 1.00 89.83 ? 70 THR M OG1 1 +ATOM 23380 C CG2 . THR M 1 70 ? 54.098 31.983 72.890 1.00 89.55 ? 70 THR M CG2 1 +ATOM 23381 N N . ALA M 1 71 ? 50.789 31.141 74.465 1.00 45.34 ? 71 ALA M N 1 +ATOM 23382 C CA . ALA M 1 71 ? 50.250 31.455 75.774 1.00 52.54 ? 71 ALA M CA 1 +ATOM 23383 C C . ALA M 1 71 ? 50.028 30.212 76.665 1.00 57.22 ? 71 ALA M C 1 +ATOM 23384 O O . ALA M 1 71 ? 50.377 30.224 77.861 1.00 62.11 ? 71 ALA M O 1 +ATOM 23385 C CB . ALA M 1 71 ? 48.939 32.184 75.623 1.00 68.84 ? 71 ALA M CB 1 +ATOM 23386 N N . LEU M 1 72 ? 49.468 29.145 76.088 1.00 54.78 ? 72 LEU M N 1 +ATOM 23387 C CA . LEU M 1 72 ? 49.365 27.861 76.797 1.00 61.36 ? 72 LEU M CA 1 +ATOM 23388 C C . LEU M 1 72 ? 50.712 27.294 77.277 1.00 74.51 ? 72 LEU M C 1 +ATOM 23389 O O . LEU M 1 72 ? 50.774 26.609 78.309 1.00 90.83 ? 72 LEU M O 1 +ATOM 23390 C CB . LEU M 1 72 ? 48.725 26.795 75.925 1.00 56.76 ? 72 LEU M CB 1 +ATOM 23391 C CG . LEU M 1 72 ? 47.291 27.080 75.572 1.00 52.65 ? 72 LEU M CG 1 +ATOM 23392 C CD1 . LEU M 1 72 ? 46.906 26.205 74.408 1.00 64.53 ? 72 LEU M CD1 1 +ATOM 23393 C CD2 . LEU M 1 72 ? 46.363 26.808 76.729 1.00 64.17 ? 72 LEU M CD2 1 +ATOM 23394 N N . LYS M 1 73 ? 51.796 27.613 76.573 1.00 74.30 ? 73 LYS M N 1 +ATOM 23395 C CA . LYS M 1 73 ? 53.116 27.201 77.022 1.00 89.25 ? 73 LYS M CA 1 +ATOM 23396 C C . LYS M 1 73 ? 53.711 28.112 78.108 1.00 118.20 ? 73 LYS M C 1 +ATOM 23397 O O . LYS M 1 73 ? 54.259 27.623 79.103 1.00 126.27 ? 73 LYS M O 1 +ATOM 23398 C CB . LYS M 1 73 ? 54.076 27.154 75.860 1.00 83.87 ? 73 LYS M CB 1 +ATOM 23399 C CG . LYS M 1 73 ? 55.371 26.467 76.213 1.00 98.45 ? 73 LYS M CG 1 +ATOM 23400 C CD . LYS M 1 73 ? 56.477 26.991 75.343 1.00 106.37 ? 73 LYS M CD 1 +ATOM 23401 C CE . LYS M 1 73 ? 57.051 28.356 75.803 1.00 115.55 ? 73 LYS M CE 1 +ATOM 23402 N NZ . LYS M 1 73 ? 58.383 28.221 76.458 1.00 118.40 ? 73 LYS M NZ 1 +ATOM 23403 N N . ASP M 1 74 ? 53.627 29.429 77.903 1.00 128.38 ? 74 ASP M N 1 +ATOM 23404 C CA . ASP M 1 74 ? 54.206 30.408 78.838 1.00 124.70 ? 74 ASP M CA 1 +ATOM 23405 C C . ASP M 1 74 ? 53.596 30.310 80.243 1.00 123.99 ? 74 ASP M C 1 +ATOM 23406 O O . ASP M 1 74 ? 54.280 30.574 81.233 1.00 139.48 ? 74 ASP M O 1 +ATOM 23407 C CB . ASP M 1 74 ? 54.013 31.830 78.321 1.00 134.56 ? 74 ASP M CB 1 +ATOM 23408 C CG . ASP M 1 74 ? 54.831 32.126 77.063 1.00 162.24 ? 74 ASP M CG 1 +ATOM 23409 O OD1 . ASP M 1 74 ? 55.918 31.529 76.861 1.00 155.21 ? 74 ASP M OD1 1 +ATOM 23410 O OD2 . ASP M 1 74 ? 54.386 33.003 76.286 1.00 187.68 ? 74 ASP M OD2 1 +ATOM 23411 N N . SER M 1 75 ? 52.346 29.843 80.324 1.00 108.32 ? 75 SER M N 1 +ATOM 23412 C CA . SER M 1 75 ? 51.637 29.683 81.605 1.00 86.94 ? 75 SER M CA 1 +ATOM 23413 C C . SER M 1 75 ? 52.270 28.646 82.533 1.00 85.13 ? 75 SER M C 1 +ATOM 23414 O O . SER M 1 75 ? 52.114 28.728 83.750 1.00 91.39 ? 75 SER M O 1 +ATOM 23415 C CB . SER M 1 75 ? 50.183 29.277 81.366 1.00 87.35 ? 75 SER M CB 1 +ATOM 23416 O OG . SER M 1 75 ? 50.047 27.865 81.243 1.00 69.05 ? 75 SER M OG 1 +ATOM 23417 N N . ARG M 1 76 ? 52.964 27.668 81.942 1.00 84.99 ? 76 ARG M N 1 +ATOM 23418 C CA . ARG M 1 76 ? 53.626 26.581 82.664 1.00 91.04 ? 76 ARG M CA 1 +ATOM 23419 C C . ARG M 1 76 ? 52.620 25.684 83.333 1.00 84.32 ? 76 ARG M C 1 +ATOM 23420 O O . ARG M 1 76 ? 52.826 25.219 84.464 1.00 155.66 ? 76 ARG M O 1 +ATOM 23421 C CB . ARG M 1 76 ? 54.650 27.120 83.677 1.00 117.61 ? 76 ARG M CB 1 +ATOM 23422 C CG . ARG M 1 76 ? 55.819 27.908 83.076 1.00 142.23 ? 76 ARG M CG 1 +ATOM 23423 C CD . ARG M 1 76 ? 56.797 28.353 84.168 1.00 143.36 ? 76 ARG M CD 1 +ATOM 23424 N NE . ARG M 1 76 ? 56.223 29.375 85.049 1.00 150.87 ? 76 ARG M NE 1 +ATOM 23425 C CZ . ARG M 1 76 ? 55.577 29.141 86.197 1.00 126.67 ? 76 ARG M CZ 1 +ATOM 23426 N NH1 . ARG M 1 76 ? 55.433 27.908 86.676 1.00 123.46 ? 76 ARG M NH1 1 +ATOM 23427 N NH2 . ARG M 1 76 ? 55.077 30.158 86.874 1.00 97.92 ? 76 ARG M NH2 1 +ATOM 23428 N N . TRP M 1 77 ? 51.494 25.531 82.669 1.00 67.31 ? 77 TRP M N 1 +ATOM 23429 C CA . TRP M 1 77 ? 50.472 24.608 83.096 1.00 76.66 ? 77 TRP M CA 1 +ATOM 23430 C C . TRP M 1 77 ? 50.320 23.496 82.057 1.00 86.55 ? 77 TRP M C 1 +ATOM 23431 O O . TRP M 1 77 ? 49.991 22.361 82.392 1.00 90.60 ? 77 TRP M O 1 +ATOM 23432 C CB . TRP M 1 77 ? 49.141 25.357 83.265 1.00 88.92 ? 77 TRP M CB 1 +ATOM 23433 C CG . TRP M 1 77 ? 48.886 25.829 84.657 1.00 99.65 ? 77 TRP M CG 1 +ATOM 23434 C CD1 . TRP M 1 77 ? 49.436 26.911 85.261 1.00 107.90 ? 77 TRP M CD1 1 +ATOM 23435 C CD2 . TRP M 1 77 ? 47.981 25.250 85.613 1.00 110.65 ? 77 TRP M CD2 1 +ATOM 23436 N NE1 . TRP M 1 77 ? 48.950 27.040 86.539 1.00 107.54 ? 77 TRP M NE1 1 +ATOM 23437 C CE2 . TRP M 1 77 ? 48.061 26.027 86.780 1.00 96.64 ? 77 TRP M CE2 1 +ATOM 23438 C CE3 . TRP M 1 77 ? 47.113 24.151 85.591 1.00 110.98 ? 77 TRP M CE3 1 +ATOM 23439 C CZ2 . TRP M 1 77 ? 47.321 25.738 87.913 1.00 97.71 ? 77 TRP M CZ2 1 +ATOM 23440 C CZ3 . TRP M 1 77 ? 46.360 23.884 86.707 1.00 102.48 ? 77 TRP M CZ3 1 +ATOM 23441 C CH2 . TRP M 1 77 ? 46.470 24.673 87.857 1.00 107.02 ? 77 TRP M CH2 1 +ATOM 23442 N N . PHE M 1 78 ? 50.512 23.856 80.786 1.00 93.61 ? 78 PHE M N 1 +ATOM 23443 C CA . PHE M 1 78 ? 50.244 22.972 79.644 1.00 71.70 ? 78 PHE M CA 1 +ATOM 23444 C C . PHE M 1 78 ? 51.492 22.713 78.796 1.00 75.58 ? 78 PHE M C 1 +ATOM 23445 O O . PHE M 1 78 ? 52.329 23.622 78.583 1.00 85.64 ? 78 PHE M O 1 +ATOM 23446 C CB . PHE M 1 78 ? 49.220 23.608 78.720 1.00 72.80 ? 78 PHE M CB 1 +ATOM 23447 C CG . PHE M 1 78 ? 47.942 23.981 79.390 1.00 79.71 ? 78 PHE M CG 1 +ATOM 23448 C CD1 . PHE M 1 78 ? 47.015 23.007 79.737 1.00 97.48 ? 78 PHE M CD1 1 +ATOM 23449 C CD2 . PHE M 1 78 ? 47.648 25.296 79.644 1.00 67.01 ? 78 PHE M CD2 1 +ATOM 23450 C CE1 . PHE M 1 78 ? 45.818 23.346 80.329 1.00 93.44 ? 78 PHE M CE1 1 +ATOM 23451 C CE2 . PHE M 1 78 ? 46.463 25.640 80.258 1.00 76.55 ? 78 PHE M CE2 1 +ATOM 23452 C CZ . PHE M 1 78 ? 45.538 24.671 80.582 1.00 86.17 ? 78 PHE M CZ 1 +ATOM 23453 N N . ILE M 1 79 ? 51.592 21.486 78.288 1.00 69.95 ? 79 ILE M N 1 +ATOM 23454 C CA . ILE M 1 79 ? 52.526 21.141 77.223 1.00 72.79 ? 79 ILE M CA 1 +ATOM 23455 C C . ILE M 1 79 ? 51.701 21.121 75.942 1.00 72.45 ? 79 ILE M C 1 +ATOM 23456 O O . ILE M 1 79 ? 50.675 20.437 75.903 1.00 58.88 ? 79 ILE M O 1 +ATOM 23457 C CB . ILE M 1 79 ? 53.116 19.740 77.414 1.00 74.94 ? 79 ILE M CB 1 +ATOM 23458 C CG1 . ILE M 1 79 ? 53.681 19.570 78.821 1.00 82.34 ? 79 ILE M CG1 1 +ATOM 23459 C CG2 . ILE M 1 79 ? 54.215 19.467 76.386 1.00 81.52 ? 79 ILE M CG2 1 +ATOM 23460 C CD1 . ILE M 1 79 ? 53.757 18.114 79.272 1.00 101.24 ? 79 ILE M CD1 1 +ATOM 23461 N N . PRO M 1 80 ? 52.113 21.919 74.922 1.00 63.64 ? 80 PRO M N 1 +ATOM 23462 C CA . PRO M 1 80 ? 51.309 21.898 73.728 1.00 57.87 ? 80 PRO M CA 1 +ATOM 23463 C C . PRO M 1 80 ? 51.841 20.911 72.752 1.00 56.67 ? 80 PRO M C 1 +ATOM 23464 O O . PRO M 1 80 ? 53.059 20.797 72.617 1.00 81.37 ? 80 PRO M O 1 +ATOM 23465 C CB . PRO M 1 80 ? 51.467 23.295 73.182 1.00 56.03 ? 80 PRO M CB 1 +ATOM 23466 C CG . PRO M 1 80 ? 51.803 24.133 74.351 1.00 64.18 ? 80 PRO M CG 1 +ATOM 23467 C CD . PRO M 1 80 ? 52.730 23.243 75.113 1.00 66.40 ? 80 PRO M CD 1 +ATOM 23468 N N . LEU M 1 81 ? 50.955 20.068 72.248 1.00 43.89 ? 81 LEU M N 1 +ATOM 23469 C CA . LEU M 1 81 ? 51.332 19.132 71.269 1.00 53.97 ? 81 LEU M CA 1 +ATOM 23470 C C . LEU M 1 81 ? 51.079 19.749 69.913 1.00 92.38 ? 81 LEU M C 1 +ATOM 23471 O O . LEU M 1 81 ? 50.079 20.491 69.722 1.00 82.97 ? 81 LEU M O 1 +ATOM 23472 C CB . LEU M 1 81 ? 50.551 17.860 71.438 1.00 53.83 ? 81 LEU M CB 1 +ATOM 23473 C CG . LEU M 1 81 ? 50.736 17.288 72.823 1.00 48.74 ? 81 LEU M CG 1 +ATOM 23474 C CD1 . LEU M 1 81 ? 49.856 16.068 72.970 1.00 55.57 ? 81 LEU M CD1 1 +ATOM 23475 C CD2 . LEU M 1 81 ? 52.170 16.896 73.039 1.00 58.81 ? 81 LEU M CD2 1 +ATOM 23476 N N . GLU M 1 82 ? 52.018 19.478 68.989 1.00 119.99 ? 82 GLU M N 1 +ATOM 23477 C CA . GLU M 1 82 ? 52.009 20.086 67.659 1.00 113.54 ? 82 GLU M CA 1 +ATOM 23478 C C . GLU M 1 82 ? 50.991 19.397 66.758 1.00 84.50 ? 82 GLU M C 1 +ATOM 23479 O O . GLU M 1 82 ? 51.210 18.279 66.288 1.00 43.78 ? 82 GLU M O 1 +ATOM 23480 C CB . GLU M 1 82 ? 53.408 20.113 67.010 1.00 90.75 ? 82 GLU M CB 1 +ATOM 23481 C CG . GLU M 1 82 ? 53.451 20.752 65.622 1.00 102.61 ? 82 GLU M CG 1 +ATOM 23482 C CD . GLU M 1 82 ? 53.244 22.287 65.611 1.00 110.30 ? 82 GLU M CD 1 +ATOM 23483 O OE1 . GLU M 1 82 ? 52.261 22.828 66.193 1.00 120.26 ? 82 GLU M OE1 1 +ATOM 23484 O OE2 . GLU M 1 82 ? 54.012 22.976 64.902 1.00 136.63 ? 82 GLU M OE2 1 +ATOM 23485 N N . ARG M 1 83 ? 49.894 20.129 66.505 1.00 85.76 ? 83 ARG M N 1 +ATOM 23486 C CA . ARG M 1 83 ? 48.894 19.737 65.532 1.00 82.58 ? 83 ARG M CA 1 +ATOM 23487 C C . ARG M 1 83 ? 48.657 20.771 64.403 1.00 77.02 ? 83 ARG M C 1 +ATOM 23488 O O . ARG M 1 83 ? 48.150 20.404 63.330 1.00 57.12 ? 83 ARG M O 1 +ATOM 23489 C CB . ARG M 1 83 ? 47.590 19.437 66.241 1.00 81.88 ? 83 ARG M CB 1 +ATOM 23490 C CG . ARG M 1 83 ? 47.727 18.393 67.350 1.00 81.39 ? 83 ARG M CG 1 +ATOM 23491 C CD . ARG M 1 83 ? 48.006 16.973 66.812 1.00 63.49 ? 83 ARG M CD 1 +ATOM 23492 N NE . ARG M 1 83 ? 47.851 15.976 67.853 1.00 57.49 ? 83 ARG M NE 1 +ATOM 23493 C CZ . ARG M 1 83 ? 48.831 15.518 68.611 1.00 76.72 ? 83 ARG M CZ 1 +ATOM 23494 N NH1 . ARG M 1 83 ? 50.100 15.769 68.306 1.00 99.17 ? 83 ARG M NH1 1 +ATOM 23495 N NH2 . ARG M 1 83 ? 48.541 14.778 69.680 1.00 93.99 ? 83 ARG M NH2 1 +ATOM 23496 N N . GLN M 1 84 ? 49.076 22.020 64.580 1.00 68.98 ? 84 GLN M N 1 +ATOM 23497 C CA . GLN M 1 84 ? 48.881 22.962 63.489 1.00 84.35 ? 84 GLN M CA 1 +ATOM 23498 C C . GLN M 1 84 ? 49.621 22.453 62.247 1.00 94.08 ? 84 GLN M C 1 +ATOM 23499 O O . GLN M 1 84 ? 49.126 22.566 61.133 1.00 109.30 ? 84 GLN M O 1 +ATOM 23500 C CB . GLN M 1 84 ? 49.290 24.394 63.865 1.00 97.23 ? 84 GLN M CB 1 +ATOM 23501 C CG . GLN M 1 84 ? 48.477 25.499 63.157 1.00 94.02 ? 84 GLN M CG 1 +ATOM 23502 C CD . GLN M 1 84 ? 48.957 26.912 63.496 1.00 129.33 ? 84 GLN M CD 1 +ATOM 23503 O OE1 . GLN M 1 84 ? 49.416 27.172 64.604 1.00 167.61 ? 84 GLN M OE1 1 +ATOM 23504 N NE2 . GLN M 1 84 ? 48.920 27.804 62.515 1.00 146.33 ? 84 GLN M NE2 1 +ATOM 23505 N N . GLY M 1 85 ? 50.830 21.945 62.417 1.00 85.11 ? 85 GLY M N 1 +ATOM 23506 C CA . GLY M 1 85 ? 51.579 21.493 61.252 1.00 90.49 ? 85 GLY M CA 1 +ATOM 23507 C C . GLY M 1 85 ? 51.681 19.989 61.176 1.00 82.00 ? 85 GLY M C 1 +ATOM 23508 O O . GLY M 1 85 ? 52.752 19.453 60.874 1.00 61.61 ? 85 GLY M O 1 +ATOM 23509 N N . LEU M 1 86 ? 50.581 19.293 61.461 1.00 79.21 ? 86 LEU M N 1 +ATOM 23510 C CA . LEU M 1 86 ? 50.657 17.844 61.787 1.00 79.73 ? 86 LEU M CA 1 +ATOM 23511 C C . LEU M 1 86 ? 51.121 17.075 60.581 1.00 90.07 ? 86 LEU M C 1 +ATOM 23512 O O . LEU M 1 86 ? 51.869 16.096 60.705 1.00 113.57 ? 86 LEU M O 1 +ATOM 23513 C CB . LEU M 1 86 ? 49.299 17.310 62.243 1.00 53.11 ? 86 LEU M CB 1 +ATOM 23514 C CG . LEU M 1 86 ? 49.103 15.823 62.394 1.00 44.54 ? 86 LEU M CG 1 +ATOM 23515 C CD1 . LEU M 1 86 ? 50.026 15.194 63.424 1.00 38.48 ? 86 LEU M CD1 1 +ATOM 23516 C CD2 . LEU M 1 86 ? 47.653 15.546 62.781 1.00 62.70 ? 86 LEU M CD2 1 +ATOM 23517 N N . GLN M 1 87 ? 50.765 17.578 59.406 1.00 90.91 ? 87 GLN M N 1 +ATOM 23518 C CA . GLN M 1 87 ? 51.084 16.869 58.170 1.00 105.20 ? 87 GLN M CA 1 +ATOM 23519 C C . GLN M 1 87 ? 52.614 16.724 57.956 1.00 108.70 ? 87 GLN M C 1 +ATOM 23520 O O . GLN M 1 87 ? 53.128 15.645 57.608 1.00 88.67 ? 87 GLN M O 1 +ATOM 23521 C CB . GLN M 1 87 ? 50.405 17.565 56.987 1.00 110.01 ? 87 GLN M CB 1 +ATOM 23522 C CG . GLN M 1 87 ? 49.951 16.606 55.889 1.00 108.36 ? 87 GLN M CG 1 +ATOM 23523 C CD . GLN M 1 87 ? 49.289 15.337 56.423 1.00 106.90 ? 87 GLN M CD 1 +ATOM 23524 O OE1 . GLN M 1 87 ? 48.293 15.399 57.156 1.00 123.19 ? 87 GLN M OE1 1 +ATOM 23525 N NE2 . GLN M 1 87 ? 49.845 14.178 56.071 1.00 97.76 ? 87 GLN M NE2 1 +ATOM 23526 N N . ASN M 1 88 ? 53.340 17.804 58.234 1.00 103.71 ? 88 ASN M N 1 +ATOM 23527 C CA . ASN M 1 88 ? 54.794 17.812 58.106 1.00 89.01 ? 88 ASN M CA 1 +ATOM 23528 C C . ASN M 1 88 ? 55.449 16.902 59.127 1.00 90.12 ? 88 ASN M C 1 +ATOM 23529 O O . ASN M 1 88 ? 56.481 16.260 58.834 1.00 138.26 ? 88 ASN M O 1 +ATOM 23530 C CB . ASN M 1 88 ? 55.337 19.213 58.332 1.00 84.19 ? 88 ASN M CB 1 +ATOM 23531 C CG . ASN M 1 88 ? 54.749 20.218 57.383 1.00 84.80 ? 88 ASN M CG 1 +ATOM 23532 O OD1 . ASN M 1 88 ? 54.502 19.907 56.230 1.00 73.49 ? 88 ASN M OD1 1 +ATOM 23533 N ND2 . ASN M 1 88 ? 54.461 21.423 57.888 1.00 97.63 ? 88 ASN M ND2 1 +ATOM 23534 N N . LEU M 1 89 ? 54.873 16.873 60.322 1.00 52.50 ? 89 LEU M N 1 +ATOM 23535 C CA . LEU M 1 89 ? 55.380 16.034 61.353 1.00 60.34 ? 89 LEU M CA 1 +ATOM 23536 C C . LEU M 1 89 ? 55.309 14.563 60.912 1.00 69.65 ? 89 LEU M C 1 +ATOM 23537 O O . LEU M 1 89 ? 56.252 13.765 61.073 1.00 115.26 ? 89 LEU M O 1 +ATOM 23538 C CB . LEU M 1 89 ? 54.550 16.273 62.605 1.00 70.95 ? 89 LEU M CB 1 +ATOM 23539 C CG . LEU M 1 89 ? 55.214 16.081 63.981 1.00 72.67 ? 89 LEU M CG 1 +ATOM 23540 C CD1 . LEU M 1 89 ? 54.548 14.953 64.734 1.00 62.85 ? 89 LEU M CD1 1 +ATOM 23541 C CD2 . LEU M 1 89 ? 56.718 15.824 63.889 1.00 53.02 ? 89 LEU M CD2 1 +ATOM 23542 N N . LEU M 1 90 ? 54.196 14.204 60.301 1.00 67.47 ? 90 LEU M N 1 +ATOM 23543 C CA . LEU M 1 90 ? 53.984 12.825 59.872 1.00 66.37 ? 90 LEU M CA 1 +ATOM 23544 C C . LEU M 1 90 ? 54.918 12.466 58.709 1.00 73.01 ? 90 LEU M C 1 +ATOM 23545 O O . LEU M 1 90 ? 55.306 11.298 58.526 1.00 58.89 ? 90 LEU M O 1 +ATOM 23546 C CB . LEU M 1 90 ? 52.512 12.621 59.476 1.00 49.75 ? 90 LEU M CB 1 +ATOM 23547 C CG . LEU M 1 90 ? 51.531 12.865 60.608 1.00 39.10 ? 90 LEU M CG 1 +ATOM 23548 C CD1 . LEU M 1 90 ? 50.159 13.084 60.028 1.00 48.45 ? 90 LEU M CD1 1 +ATOM 23549 C CD2 . LEU M 1 90 ? 51.532 11.697 61.565 1.00 38.28 ? 90 LEU M CD2 1 +ATOM 23550 N N . ASN M 1 91 ? 55.208 13.471 57.894 1.00 86.89 ? 91 ASN M N 1 +ATOM 23551 C CA . ASN M 1 91 ? 56.081 13.297 56.759 1.00 101.79 ? 91 ASN M CA 1 +ATOM 23552 C C . ASN M 1 91 ? 57.510 13.030 57.218 1.00 97.42 ? 91 ASN M C 1 +ATOM 23553 O O . ASN M 1 91 ? 58.162 12.085 56.739 1.00 122.79 ? 91 ASN M O 1 +ATOM 23554 C CB . ASN M 1 91 ? 56.029 14.556 55.906 1.00 106.53 ? 91 ASN M CB 1 +ATOM 23555 C CG . ASN M 1 91 ? 55.521 14.324 54.515 1.00 137.72 ? 91 ASN M CG 1 +ATOM 23556 O OD1 . ASN M 1 91 ? 54.800 13.359 54.221 1.00 122.04 ? 91 ASN M OD1 1 +ATOM 23557 N ND2 . ASN M 1 91 ? 55.883 15.250 53.637 1.00 172.41 ? 91 ASN M ND2 1 +ATOM 23558 N N . GLU M 1 92 ? 58.007 13.850 58.135 1.00 74.04 ? 92 GLU M N 1 +ATOM 23559 C CA . GLU M 1 92 ? 59.342 13.614 58.690 1.00 76.54 ? 92 GLU M CA 1 +ATOM 23560 C C . GLU M 1 92 ? 59.433 12.202 59.283 1.00 70.98 ? 92 GLU M C 1 +ATOM 23561 O O . GLU M 1 92 ? 60.496 11.563 59.236 1.00 63.65 ? 92 GLU M O 1 +ATOM 23562 C CB . GLU M 1 92 ? 59.717 14.676 59.743 1.00 71.88 ? 92 GLU M CB 1 +ATOM 23563 C CG . GLU M 1 92 ? 60.466 15.863 59.172 1.00 87.15 ? 92 GLU M CG 1 +ATOM 23564 C CD . GLU M 1 92 ? 61.725 15.472 58.361 1.00 80.10 ? 92 GLU M CD 1 +ATOM 23565 O OE1 . GLU M 1 92 ? 62.648 14.814 58.878 1.00 57.30 ? 92 GLU M OE1 1 +ATOM 23566 O OE2 . GLU M 1 92 ? 61.830 15.877 57.183 1.00 67.66 ? 92 GLU M OE2 1 +ATOM 23567 N N . ARG M 1 93 ? 58.333 11.738 59.877 1.00 61.01 ? 93 ARG M N 1 +ATOM 23568 C CA . ARG M 1 93 ? 58.331 10.438 60.525 1.00 67.25 ? 93 ARG M CA 1 +ATOM 23569 C C . ARG M 1 93 ? 58.349 9.338 59.472 1.00 96.12 ? 93 ARG M C 1 +ATOM 23570 O O . ARG M 1 93 ? 59.002 8.307 59.659 1.00 122.91 ? 93 ARG M O 1 +ATOM 23571 C CB . ARG M 1 93 ? 57.149 10.330 61.478 1.00 63.26 ? 93 ARG M CB 1 +ATOM 23572 C CG . ARG M 1 93 ? 57.333 11.204 62.704 1.00 99.19 ? 93 ARG M CG 1 +ATOM 23573 C CD . ARG M 1 93 ? 56.078 11.424 63.532 1.00 111.80 ? 93 ARG M CD 1 +ATOM 23574 N NE . ARG M 1 93 ? 56.059 10.576 64.721 1.00 111.24 ? 93 ARG M NE 1 +ATOM 23575 C CZ . ARG M 1 93 ? 55.491 9.383 64.784 1.00 105.49 ? 93 ARG M CZ 1 +ATOM 23576 N NH1 . ARG M 1 93 ? 54.780 8.895 63.753 1.00 103.03 ? 93 ARG M NH1 1 +ATOM 23577 N NH2 . ARG M 1 93 ? 55.568 8.723 65.927 1.00 82.53 ? 93 ARG M NH2 1 +ATOM 23578 N N . LYS M 1 94 ? 57.729 9.591 58.318 1.00 93.39 ? 94 LYS M N 1 +ATOM 23579 C CA . LYS M 1 94 ? 57.846 8.660 57.185 1.00 74.81 ? 94 LYS M CA 1 +ATOM 23580 C C . LYS M 1 94 ? 59.299 8.565 56.713 1.00 79.47 ? 94 LYS M C 1 +ATOM 23581 O O . LYS M 1 94 ? 59.799 7.468 56.421 1.00 66.35 ? 94 LYS M O 1 +ATOM 23582 C CB . LYS M 1 94 ? 57.005 9.131 56.019 1.00 85.55 ? 94 LYS M CB 1 +ATOM 23583 C CG . LYS M 1 94 ? 55.565 8.668 56.022 1.00 117.26 ? 94 LYS M CG 1 +ATOM 23584 C CD . LYS M 1 94 ? 54.791 9.366 54.905 1.00 132.92 ? 94 LYS M CD 1 +ATOM 23585 C CE . LYS M 1 94 ? 53.517 8.631 54.518 1.00 134.54 ? 94 LYS M CE 1 +ATOM 23586 N NZ . LYS M 1 94 ? 52.641 9.517 53.701 1.00 144.68 ? 94 LYS M NZ 1 +ATOM 23587 N N . ILE M 1 95 ? 59.989 9.711 56.670 1.00 79.73 ? 95 ILE M N 1 +ATOM 23588 C CA . ILE M 1 95 ? 61.356 9.742 56.152 1.00 83.59 ? 95 ILE M CA 1 +ATOM 23589 C C . ILE M 1 95 ? 62.332 9.082 57.104 1.00 79.74 ? 95 ILE M C 1 +ATOM 23590 O O . ILE M 1 95 ? 63.256 8.359 56.649 1.00 86.31 ? 95 ILE M O 1 +ATOM 23591 C CB . ILE M 1 95 ? 61.880 11.160 55.884 1.00 90.85 ? 95 ILE M CB 1 +ATOM 23592 C CG1 . ILE M 1 95 ? 60.858 11.987 55.092 1.00 87.70 ? 95 ILE M CG1 1 +ATOM 23593 C CG2 . ILE M 1 95 ? 63.166 11.049 55.077 1.00 104.10 ? 95 ILE M CG2 1 +ATOM 23594 C CD1 . ILE M 1 95 ? 61.410 13.275 54.502 1.00 93.75 ? 95 ILE M CD1 1 +ATOM 23595 N N . ILE M 1 96 ? 62.116 9.337 58.408 1.00 57.03 ? 96 ILE M N 1 +ATOM 23596 C CA . ILE M 1 96 ? 62.843 8.652 59.465 1.00 41.70 ? 96 ILE M CA 1 +ATOM 23597 C C . ILE M 1 96 ? 62.694 7.146 59.306 1.00 52.65 ? 96 ILE M C 1 +ATOM 23598 O O . ILE M 1 96 ? 63.682 6.427 59.129 1.00 55.00 ? 96 ILE M O 1 +ATOM 23599 C CB . ILE M 1 96 ? 62.364 9.031 60.834 1.00 29.72 ? 96 ILE M CB 1 +ATOM 23600 C CG1 . ILE M 1 96 ? 62.700 10.455 61.126 1.00 29.07 ? 96 ILE M CG1 1 +ATOM 23601 C CG2 . ILE M 1 96 ? 63.067 8.179 61.854 1.00 26.90 ? 96 ILE M CG2 1 +ATOM 23602 C CD1 . ILE M 1 96 ? 62.313 10.892 62.529 1.00 34.92 ? 96 ILE M CD1 1 +ATOM 23603 N N . ARG M 1 97 ? 61.451 6.662 59.294 1.00 53.84 ? 97 ARG M N 1 +ATOM 23604 C CA . ARG M 1 97 ? 61.200 5.204 59.244 1.00 67.38 ? 97 ARG M CA 1 +ATOM 23605 C C . ARG M 1 97 ? 61.761 4.563 57.965 1.00 63.48 ? 97 ARG M C 1 +ATOM 23606 O O . ARG M 1 97 ? 62.185 3.402 57.968 1.00 49.97 ? 97 ARG M O 1 +ATOM 23607 C CB . ARG M 1 97 ? 59.696 4.892 59.363 1.00 88.78 ? 97 ARG M CB 1 +ATOM 23608 C CG . ARG M 1 97 ? 59.233 4.387 60.737 1.00 67.38 ? 97 ARG M CG 1 +ATOM 23609 C CD . ARG M 1 97 ? 57.750 4.049 60.715 1.00 69.65 ? 97 ARG M CD 1 +ATOM 23610 N NE . ARG M 1 97 ? 56.896 5.230 60.856 1.00 71.49 ? 97 ARG M NE 1 +ATOM 23611 C CZ . ARG M 1 97 ? 56.336 5.631 61.999 1.00 88.51 ? 97 ARG M CZ 1 +ATOM 23612 N NH1 . ARG M 1 97 ? 56.489 4.919 63.122 1.00 66.34 ? 97 ARG M NH1 1 +ATOM 23613 N NH2 . ARG M 1 97 ? 55.600 6.754 62.014 1.00 101.70 ? 97 ARG M NH2 1 +ATOM 23614 N N . ALA M 1 98 ? 61.783 5.332 56.886 1.00 65.52 ? 98 ALA M N 1 +ATOM 23615 C CA . ALA M 1 98 ? 62.343 4.844 55.643 1.00 91.43 ? 98 ALA M CA 1 +ATOM 23616 C C . ALA M 1 98 ? 63.874 4.802 55.707 1.00 95.36 ? 98 ALA M C 1 +ATOM 23617 O O . ALA M 1 98 ? 64.514 3.983 55.032 1.00 58.29 ? 98 ALA M O 1 +ATOM 23618 C CB . ALA M 1 98 ? 61.879 5.727 54.503 1.00 126.72 ? 98 ALA M CB 1 +ATOM 23619 N N . ALA M 1 99 ? 64.440 5.685 56.538 1.00 118.81 ? 99 ALA M N 1 +ATOM 23620 C CA . ALA M 1 99 ? 65.895 5.794 56.703 1.00 113.97 ? 99 ALA M CA 1 +ATOM 23621 C C . ALA M 1 99 ? 66.474 4.603 57.432 1.00 99.82 ? 99 ALA M C 1 +ATOM 23622 O O . ALA M 1 99 ? 67.426 3.973 56.974 1.00 99.06 ? 99 ALA M O 1 +ATOM 23623 C CB . ALA M 1 99 ? 66.255 7.067 57.451 1.00 113.23 ? 99 ALA M CB 1 +ATOM 23624 N N . GLN M 1 100 ? 65.867 4.278 58.561 1.00 113.26 ? 100 GLN M N 1 +ATOM 23625 C CA . GLN M 1 100 ? 66.499 3.377 59.521 1.00 124.20 ? 100 GLN M CA 1 +ATOM 23626 C C . GLN M 1 100 ? 65.876 1.984 59.571 1.00 99.68 ? 100 GLN M C 1 +ATOM 23627 O O . GLN M 1 100 ? 66.263 1.161 60.417 1.00 130.10 ? 100 GLN M O 1 +ATOM 23628 C CB . GLN M 1 100 ? 66.503 4.003 60.922 1.00 117.82 ? 100 GLN M CB 1 +ATOM 23629 C CG . GLN M 1 100 ? 65.195 4.680 61.318 1.00 81.52 ? 100 GLN M CG 1 +ATOM 23630 C CD . GLN M 1 100 ? 65.374 5.801 62.305 1.00 64.69 ? 100 GLN M CD 1 +ATOM 23631 O OE1 . GLN M 1 100 ? 66.117 6.780 62.088 1.00 58.40 ? 100 GLN M OE1 1 +ATOM 23632 N NE2 . GLN M 1 100 ? 64.761 5.618 63.464 1.00 71.00 ? 100 GLN M NE2 1 +ATOM 23633 N N . GLU M 1 101 ? 64.965 1.698 58.646 1.00 73.82 ? 101 GLU M N 1 +ATOM 23634 C CA . GLU M 1 101 ? 64.298 0.389 58.631 1.00 89.08 ? 101 GLU M CA 1 +ATOM 23635 C C . GLU M 1 101 ? 65.238 -0.771 58.289 1.00 88.98 ? 101 GLU M C 1 +ATOM 23636 O O . GLU M 1 101 ? 64.982 -1.915 58.652 1.00 68.84 ? 101 GLU M O 1 +ATOM 23637 C CB . GLU M 1 101 ? 63.104 0.395 57.680 1.00 93.47 ? 101 GLU M CB 1 +ATOM 23638 C CG . GLU M 1 101 ? 63.419 0.869 56.274 1.00 109.74 ? 101 GLU M CG 1 +ATOM 23639 C CD . GLU M 1 101 ? 62.219 0.750 55.340 1.00 109.44 ? 101 GLU M CD 1 +ATOM 23640 O OE1 . GLU M 1 101 ? 61.086 0.684 55.847 1.00 101.22 ? 101 GLU M OE1 1 +ATOM 23641 O OE2 . GLU M 1 101 ? 62.406 0.836 54.104 1.00 106.45 ? 101 GLU M OE2 1 +ATOM 23642 N N . ASN M 1 102 ? 66.341 -0.473 57.613 1.00 109.68 ? 102 ASN M N 1 +ATOM 23643 C CA . ASN M 1 102 ? 67.277 -1.516 57.204 1.00 105.25 ? 102 ASN M CA 1 +ATOM 23644 C C . ASN M 1 102 ? 68.402 -1.762 58.196 1.00 98.22 ? 102 ASN M C 1 +ATOM 23645 O O . ASN M 1 102 ? 69.249 -2.624 57.974 1.00 100.02 ? 102 ASN M O 1 +ATOM 23646 C CB . ASN M 1 102 ? 67.861 -1.175 55.837 1.00 104.51 ? 102 ASN M CB 1 +ATOM 23647 C CG . ASN M 1 102 ? 66.844 -1.331 54.737 1.00 100.70 ? 102 ASN M CG 1 +ATOM 23648 O OD1 . ASN M 1 102 ? 66.531 -2.456 54.300 1.00 75.53 ? 102 ASN M OD1 1 +ATOM 23649 N ND2 . ASN M 1 102 ? 66.271 -0.207 54.317 1.00 99.62 ? 102 ASN M ND2 1 +ATOM 23650 N N . GLY M 1 103 ? 68.447 -0.976 59.262 1.00 102.62 ? 103 GLY M N 1 +ATOM 23651 C CA . GLY M 1 103 ? 69.514 -1.108 60.251 1.00 114.85 ? 103 GLY M CA 1 +ATOM 23652 C C . GLY M 1 103 ? 70.920 -0.901 59.706 1.00 102.97 ? 103 GLY M C 1 +ATOM 23653 O O . GLY M 1 103 ? 71.877 -1.549 60.152 1.00 117.68 ? 103 GLY M O 1 +ATOM 23654 N N . THR M 1 104 ? 71.050 -0.007 58.733 1.00 78.46 ? 104 THR M N 1 +ATOM 23655 C CA . THR M 1 104 ? 72.363 0.431 58.302 1.00 73.76 ? 104 THR M CA 1 +ATOM 23656 C C . THR M 1 104 ? 72.655 1.770 58.933 1.00 72.38 ? 104 THR M C 1 +ATOM 23657 O O . THR M 1 104 ? 73.817 2.105 59.136 1.00 108.53 ? 104 THR M O 1 +ATOM 23658 C CB . THR M 1 104 ? 72.496 0.511 56.771 1.00 76.12 ? 104 THR M CB 1 +ATOM 23659 O OG1 . THR M 1 104 ? 71.593 1.503 56.238 1.00 105.54 ? 104 THR M OG1 1 +ATOM 23660 C CG2 . THR M 1 104 ? 72.182 -0.846 56.156 1.00 89.03 ? 104 THR M CG2 1 +ATOM 23661 N N . VAL M 1 105 ? 71.621 2.530 59.297 1.00 79.21 ? 105 VAL M N 1 +ATOM 23662 C CA . VAL M 1 105 ? 71.830 3.950 59.698 1.00 104.68 ? 105 VAL M CA 1 +ATOM 23663 C C . VAL M 1 105 ? 72.694 4.009 60.953 1.00 91.47 ? 105 VAL M C 1 +ATOM 23664 O O . VAL M 1 105 ? 72.568 3.150 61.836 1.00 86.39 ? 105 VAL M O 1 +ATOM 23665 C CB . VAL M 1 105 ? 70.496 4.766 59.872 1.00 109.53 ? 105 VAL M CB 1 +ATOM 23666 C CG1 . VAL M 1 105 ? 70.605 5.773 61.017 1.00 96.98 ? 105 VAL M CG1 1 +ATOM 23667 C CG2 . VAL M 1 105 ? 70.100 5.485 58.562 1.00 79.26 ? 105 VAL M CG2 1 +ATOM 23668 N N . ALA M 1 106 ? 73.602 4.988 60.971 1.00 93.36 ? 106 ALA M N 1 +ATOM 23669 C CA . ALA M 1 106 ? 74.636 5.095 61.985 1.00 117.34 ? 106 ALA M CA 1 +ATOM 23670 C C . ALA M 1 106 ? 74.014 5.278 63.370 1.00 146.98 ? 106 ALA M C 1 +ATOM 23671 O O . ALA M 1 106 ? 73.097 6.085 63.546 1.00 202.84 ? 106 ALA M O 1 +ATOM 23672 C CB . ALA M 1 106 ? 75.561 6.255 61.659 1.00 109.67 ? 106 ALA M CB 1 +ATOM 23673 N N . ILE M 1 107 ? 74.520 4.522 64.343 1.00 145.88 ? 107 ILE M N 1 +ATOM 23674 C CA . ILE M 1 107 ? 73.938 4.480 65.684 1.00 146.42 ? 107 ILE M CA 1 +ATOM 23675 C C . ILE M 1 107 ? 73.880 5.874 66.357 1.00 125.24 ? 107 ILE M C 1 +ATOM 23676 O O . ILE M 1 107 ? 72.990 6.153 67.166 1.00 85.02 ? 107 ILE M O 1 +ATOM 23677 C CB . ILE M 1 107 ? 74.705 3.464 66.572 1.00 142.27 ? 107 ILE M CB 1 +ATOM 23678 C CG1 . ILE M 1 107 ? 73.935 3.171 67.868 1.00 150.20 ? 107 ILE M CG1 1 +ATOM 23679 C CG2 . ILE M 1 107 ? 76.113 3.967 66.882 1.00 137.14 ? 107 ILE M CG2 1 +ATOM 23680 C CD1 . ILE M 1 107 ? 72.524 2.640 67.661 1.00 132.14 ? 107 ILE M CD1 1 +ATOM 23681 N N . ASN M 1 108 ? 74.840 6.732 66.024 1.00 113.70 ? 108 ASN M N 1 +ATOM 23682 C CA . ASN M 1 108 ? 74.868 8.112 66.520 1.00 129.26 ? 108 ASN M CA 1 +ATOM 23683 C C . ASN M 1 108 ? 73.760 8.939 65.880 1.00 128.30 ? 108 ASN M C 1 +ATOM 23684 O O . ASN M 1 108 ? 73.189 9.832 66.504 1.00 130.49 ? 108 ASN M O 1 +ATOM 23685 C CB . ASN M 1 108 ? 76.217 8.778 66.203 1.00 148.08 ? 108 ASN M CB 1 +ATOM 23686 C CG . ASN M 1 108 ? 77.372 7.793 66.184 1.00 155.14 ? 108 ASN M CG 1 +ATOM 23687 O OD1 . ASN M 1 108 ? 77.966 7.501 67.218 1.00 204.49 ? 108 ASN M OD1 1 +ATOM 23688 N ND2 . ASN M 1 108 ? 77.686 7.265 65.006 1.00 156.86 ? 108 ASN M ND2 1 +ATOM 23689 N N . ASN M 1 109 ? 73.486 8.641 64.618 1.00 123.85 ? 109 ASN M N 1 +ATOM 23690 C CA . ASN M 1 109 ? 72.534 9.402 63.821 1.00 121.04 ? 109 ASN M CA 1 +ATOM 23691 C C . ASN M 1 109 ? 71.085 8.927 63.987 1.00 108.76 ? 109 ASN M C 1 +ATOM 23692 O O . ASN M 1 109 ? 70.149 9.647 63.646 1.00 97.78 ? 109 ASN M O 1 +ATOM 23693 C CB . ASN M 1 109 ? 72.932 9.325 62.346 1.00 138.78 ? 109 ASN M CB 1 +ATOM 23694 C CG . ASN M 1 109 ? 73.312 10.676 61.781 1.00 166.25 ? 109 ASN M CG 1 +ATOM 23695 O OD1 . ASN M 1 109 ? 72.623 11.205 60.912 1.00 220.75 ? 109 ASN M OD1 1 +ATOM 23696 N ND2 . ASN M 1 109 ? 74.385 11.260 62.302 1.00 170.33 ? 109 ASN M ND2 1 +ATOM 23697 N N . ARG M 1 110 ? 70.920 7.723 64.533 1.00 103.87 ? 110 ARG M N 1 +ATOM 23698 C CA . ARG M 1 110 ? 69.618 7.057 64.640 1.00 79.62 ? 110 ARG M CA 1 +ATOM 23699 C C . ARG M 1 110 ? 68.620 7.932 65.394 1.00 75.83 ? 110 ARG M C 1 +ATOM 23700 O O . ARG M 1 110 ? 68.930 8.469 66.470 1.00 96.19 ? 110 ARG M O 1 +ATOM 23701 C CB . ARG M 1 110 ? 69.804 5.717 65.385 1.00 77.42 ? 110 ARG M CB 1 +ATOM 23702 C CG . ARG M 1 110 ? 68.732 4.684 65.112 1.00 92.20 ? 110 ARG M CG 1 +ATOM 23703 C CD . ARG M 1 110 ? 69.296 3.263 65.109 1.00 113.35 ? 110 ARG M CD 1 +ATOM 23704 N NE . ARG M 1 110 ? 69.287 2.636 66.430 1.00 132.75 ? 110 ARG M NE 1 +ATOM 23705 C CZ . ARG M 1 110 ? 68.581 1.542 66.756 1.00 162.42 ? 110 ARG M CZ 1 +ATOM 23706 N NH1 . ARG M 1 110 ? 67.825 0.894 65.855 1.00 119.87 ? 110 ARG M NH1 1 +ATOM 23707 N NH2 . ARG M 1 110 ? 68.634 1.084 68.006 1.00 184.36 ? 110 ARG M NH2 1 +ATOM 23708 N N . ILE M 1 111 ? 67.406 8.035 64.880 1.00 65.10 ? 111 ILE M N 1 +ATOM 23709 C CA . ILE M 1 111 ? 66.316 8.711 65.620 1.00 77.85 ? 111 ILE M CA 1 +ATOM 23710 C C . ILE M 1 111 ? 65.279 7.713 66.125 1.00 71.03 ? 111 ILE M C 1 +ATOM 23711 O O . ILE M 1 111 ? 64.631 7.066 65.321 1.00 92.17 ? 111 ILE M O 1 +ATOM 23712 C CB . ILE M 1 111 ? 65.585 9.751 64.744 1.00 73.34 ? 111 ILE M CB 1 +ATOM 23713 C CG1 . ILE M 1 111 ? 66.576 10.837 64.344 1.00 95.41 ? 111 ILE M CG1 1 +ATOM 23714 C CG2 . ILE M 1 111 ? 64.399 10.344 65.484 1.00 58.66 ? 111 ILE M CG2 1 +ATOM 23715 C CD1 . ILE M 1 111 ? 66.085 11.756 63.245 1.00 102.25 ? 111 ILE M CD1 1 +ATOM 23716 N N . PRO M 1 112 ? 65.118 7.601 67.445 1.00 69.97 ? 112 PRO M N 1 +ATOM 23717 C CA . PRO M 1 112 ? 64.181 6.647 67.976 1.00 77.54 ? 112 PRO M CA 1 +ATOM 23718 C C . PRO M 1 112 ? 62.758 7.197 67.897 1.00 83.97 ? 112 PRO M C 1 +ATOM 23719 O O . PRO M 1 112 ? 62.489 8.318 68.353 1.00 91.29 ? 112 PRO M O 1 +ATOM 23720 C CB . PRO M 1 112 ? 64.641 6.503 69.424 1.00 104.64 ? 112 PRO M CB 1 +ATOM 23721 C CG . PRO M 1 112 ? 65.206 7.859 69.781 1.00 89.46 ? 112 PRO M CG 1 +ATOM 23722 C CD . PRO M 1 112 ? 65.716 8.447 68.500 1.00 81.28 ? 112 PRO M CD 1 +ATOM 23723 N N . LEU M 1 113 ? 61.848 6.378 67.386 1.00 103.10 ? 113 LEU M N 1 +ATOM 23724 C CA . LEU M 1 113 ? 60.484 6.803 67.146 1.00 110.63 ? 113 LEU M CA 1 +ATOM 23725 C C . LEU M 1 113 ? 59.493 6.164 68.115 1.00 99.31 ? 113 LEU M C 1 +ATOM 23726 O O . LEU M 1 113 ? 59.501 4.951 68.374 1.00 76.25 ? 113 LEU M O 1 +ATOM 23727 C CB . LEU M 1 113 ? 60.069 6.503 65.700 1.00 132.53 ? 113 LEU M CB 1 +ATOM 23728 C CG . LEU M 1 113 ? 60.440 7.567 64.675 1.00 146.27 ? 113 LEU M CG 1 +ATOM 23729 C CD1 . LEU M 1 113 ? 59.865 7.145 63.336 1.00 138.85 ? 113 LEU M CD1 1 +ATOM 23730 C CD2 . LEU M 1 113 ? 59.935 8.954 65.050 1.00 155.87 ? 113 LEU M CD2 1 +ATOM 23731 N N . GLN M 1 114 ? 58.531 6.988 68.492 1.00 97.93 ? 114 GLN M N 1 +ATOM 23732 C CA . GLN M 1 114 ? 57.584 6.661 69.517 1.00 77.00 ? 114 GLN M CA 1 +ATOM 23733 C C . GLN M 1 114 ? 56.263 7.260 69.066 1.00 76.27 ? 114 GLN M C 1 +ATOM 23734 O O . GLN M 1 114 ? 56.251 8.228 68.316 1.00 76.65 ? 114 GLN M O 1 +ATOM 23735 C CB . GLN M 1 114 ? 58.037 7.322 70.801 1.00 72.08 ? 114 GLN M CB 1 +ATOM 23736 C CG . GLN M 1 114 ? 57.656 6.552 72.021 1.00 83.60 ? 114 GLN M CG 1 +ATOM 23737 C CD . GLN M 1 114 ? 57.512 7.461 73.190 1.00 98.36 ? 114 GLN M CD 1 +ATOM 23738 O OE1 . GLN M 1 114 ? 58.173 8.512 73.255 1.00 103.22 ? 114 GLN M OE1 1 +ATOM 23739 N NE2 . GLN M 1 114 ? 56.607 7.102 74.121 1.00 104.40 ? 114 GLN M NE2 1 +ATOM 23740 N N . SER M 1 115 ? 55.162 6.631 69.454 1.00 79.87 ? 115 SER M N 1 +ATOM 23741 C CA . SER M 1 115 ? 53.821 7.015 68.987 1.00 59.70 ? 115 SER M CA 1 +ATOM 23742 C C . SER M 1 115 ? 53.597 8.443 69.360 1.00 68.48 ? 115 SER M C 1 +ATOM 23743 O O . SER M 1 115 ? 54.240 8.968 70.299 1.00 100.70 ? 115 SER M O 1 +ATOM 23744 C CB . SER M 1 115 ? 52.741 6.129 69.628 1.00 59.28 ? 115 SER M CB 1 +ATOM 23745 O OG . SER M 1 115 ? 52.890 6.046 71.061 1.00 74.14 ? 115 SER M OG 1 +ATOM 23746 N N . LEU M 1 116 ? 52.692 9.104 68.656 1.00 97.15 ? 116 LEU M N 1 +ATOM 23747 C CA . LEU M 1 116 ? 52.625 10.561 68.797 1.00 115.95 ? 116 LEU M CA 1 +ATOM 23748 C C . LEU M 1 116 ? 51.941 10.863 70.110 1.00 97.13 ? 116 LEU M C 1 +ATOM 23749 O O . LEU M 1 116 ? 50.928 10.238 70.395 1.00 89.09 ? 116 LEU M O 1 +ATOM 23750 C CB . LEU M 1 116 ? 51.845 11.187 67.652 1.00 111.92 ? 116 LEU M CB 1 +ATOM 23751 C CG . LEU M 1 116 ? 52.475 11.119 66.251 1.00 87.25 ? 116 LEU M CG 1 +ATOM 23752 C CD1 . LEU M 1 116 ? 51.959 9.912 65.456 1.00 57.36 ? 116 LEU M CD1 1 +ATOM 23753 C CD2 . LEU M 1 116 ? 52.191 12.423 65.537 1.00 70.82 ? 116 LEU M CD2 1 +ATOM 23754 N N . THR M 1 117 ? 52.589 11.661 70.958 1.00 79.03 ? 117 THR M N 1 +ATOM 23755 C CA . THR M 1 117 ? 52.095 11.923 72.306 1.00 81.58 ? 117 THR M CA 1 +ATOM 23756 C C . THR M 1 117 ? 50.729 12.481 72.117 1.00 68.66 ? 117 THR M C 1 +ATOM 23757 O O . THR M 1 117 ? 50.560 13.378 71.279 1.00 52.81 ? 117 THR M O 1 +ATOM 23758 C CB . THR M 1 117 ? 52.956 12.971 73.062 1.00 97.31 ? 117 THR M CB 1 +ATOM 23759 O OG1 . THR M 1 117 ? 54.312 12.521 73.124 1.00 109.52 ? 117 THR M OG1 1 +ATOM 23760 C CG2 . THR M 1 117 ? 52.450 13.191 74.485 1.00 89.14 ? 117 THR M CG2 1 +ATOM 23761 N N . ALA M 1 118 ? 49.773 11.980 72.911 1.00 55.73 ? 118 ALA M N 1 +ATOM 23762 C CA . ALA M 1 118 ? 48.359 12.302 72.717 1.00 50.84 ? 118 ALA M CA 1 +ATOM 23763 C C . ALA M 1 118 ? 47.732 13.095 73.817 1.00 47.97 ? 118 ALA M C 1 +ATOM 23764 O O . ALA M 1 118 ? 48.016 12.857 74.999 1.00 40.97 ? 118 ALA M O 1 +ATOM 23765 C CB . ALA M 1 118 ? 47.579 11.042 72.558 1.00 49.21 ? 118 ALA M CB 1 +ATOM 23766 N N . ALA M 1 119 ? 46.865 14.027 73.418 1.00 49.38 ? 119 ALA M N 1 +ATOM 23767 C CA . ALA M 1 119 ? 46.343 15.033 74.348 1.00 76.87 ? 119 ALA M CA 1 +ATOM 23768 C C . ALA M 1 119 ? 45.086 14.527 75.026 1.00 112.44 ? 119 ALA M C 1 +ATOM 23769 O O . ALA M 1 119 ? 44.392 13.671 74.462 1.00 110.19 ? 119 ALA M O 1 +ATOM 23770 C CB . ALA M 1 119 ? 46.051 16.328 73.612 1.00 69.25 ? 119 ALA M CB 1 +ATOM 23771 N N . ASN M 1 120 ? 44.780 15.049 76.223 1.00 126.61 ? 120 ASN M N 1 +ATOM 23772 C CA . ASN M 1 120 ? 43.511 14.711 76.873 1.00 143.87 ? 120 ASN M CA 1 +ATOM 23773 C C . ASN M 1 120 ? 42.422 15.754 76.665 1.00 131.91 ? 120 ASN M C 1 +ATOM 23774 O O . ASN M 1 120 ? 41.265 15.430 76.385 1.00 115.18 ? 120 ASN M O 1 +ATOM 23775 C CB . ASN M 1 120 ? 43.664 14.484 78.369 1.00 143.06 ? 120 ASN M CB 1 +ATOM 23776 C CG . ASN M 1 120 ? 42.344 14.034 79.017 1.00 152.34 ? 120 ASN M CG 1 +ATOM 23777 O OD1 . ASN M 1 120 ? 42.022 14.476 80.108 1.00 209.50 ? 120 ASN M OD1 1 +ATOM 23778 N ND2 . ASN M 1 120 ? 41.553 13.196 78.317 1.00 121.04 ? 120 ASN M ND2 1 +ATOM 23779 N N . ILE M 1 121 ? 42.777 17.010 76.873 1.00 128.44 ? 121 ILE M N 1 +ATOM 23780 C CA . ILE M 1 121 ? 41.862 18.092 76.554 1.00 123.84 ? 121 ILE M CA 1 +ATOM 23781 C C . ILE M 1 121 ? 42.423 18.817 75.353 1.00 112.89 ? 121 ILE M C 1 +ATOM 23782 O O . ILE M 1 121 ? 43.625 18.947 75.187 1.00 142.02 ? 121 ILE M O 1 +ATOM 23783 C CB . ILE M 1 121 ? 41.645 19.070 77.736 1.00 108.30 ? 121 ILE M CB 1 +ATOM 23784 C CG1 . ILE M 1 121 ? 42.864 19.958 77.970 1.00 85.70 ? 121 ILE M CG1 1 +ATOM 23785 C CG2 . ILE M 1 121 ? 41.284 18.297 78.996 1.00 135.47 ? 121 ILE M CG2 1 +ATOM 23786 C CD1 . ILE M 1 121 ? 42.630 21.394 77.609 1.00 77.24 ? 121 ILE M CD1 1 +ATOM 23787 N N . MET M 1 122 ? 41.550 19.196 74.452 1.00 95.46 ? 122 MET M N 1 +ATOM 23788 C CA . MET M 1 122 ? 41.968 20.093 73.437 1.00 77.13 ? 122 MET M CA 1 +ATOM 23789 C C . MET M 1 122 ? 41.160 21.375 73.593 1.00 74.46 ? 122 MET M C 1 +ATOM 23790 O O . MET M 1 122 ? 39.971 21.350 73.900 1.00 91.44 ? 122 MET M O 1 +ATOM 23791 C CB . MET M 1 122 ? 41.877 19.419 72.062 1.00 61.74 ? 122 MET M CB 1 +ATOM 23792 C CG . MET M 1 122 ? 40.518 18.877 71.677 1.00 71.46 ? 122 MET M CG 1 +ATOM 23793 S SD . MET M 1 122 ? 40.360 18.798 69.873 1.00 110.81 ? 122 MET M SD 1 +ATOM 23794 C CE . MET M 1 122 ? 38.679 19.467 69.699 1.00 99.18 ? 122 MET M CE 1 +ATOM 23795 N N . VAL M 1 123 ? 41.809 22.505 73.350 1.00 70.51 ? 123 VAL M N 1 +ATOM 23796 C CA . VAL M 1 123 ? 41.131 23.804 73.372 1.00 70.59 ? 123 VAL M CA 1 +ATOM 23797 C C . VAL M 1 123 ? 41.101 24.514 72.013 1.00 68.36 ? 123 VAL M C 1 +ATOM 23798 O O . VAL M 1 123 ? 42.110 24.653 71.361 1.00 60.76 ? 123 VAL M O 1 +ATOM 23799 C CB . VAL M 1 123 ? 41.805 24.763 74.355 1.00 62.45 ? 123 VAL M CB 1 +ATOM 23800 C CG1 . VAL M 1 123 ? 43.307 24.652 74.256 1.00 55.66 ? 123 VAL M CG1 1 +ATOM 23801 C CG2 . VAL M 1 123 ? 41.324 26.205 74.143 1.00 59.56 ? 123 VAL M CG2 1 +ATOM 23802 N N . GLU M 1 124 ? 39.906 24.887 71.575 1.00 82.23 ? 124 GLU M N 1 +ATOM 23803 C CA . GLU M 1 124 ? 39.753 25.642 70.353 1.00 78.35 ? 124 GLU M CA 1 +ATOM 23804 C C . GLU M 1 124 ? 38.923 26.859 70.621 1.00 81.28 ? 124 GLU M C 1 +ATOM 23805 O O . GLU M 1 124 ? 38.308 27.001 71.668 1.00 118.31 ? 124 GLU M O 1 +ATOM 23806 C CB . GLU M 1 124 ? 39.107 24.807 69.234 1.00 70.77 ? 124 GLU M CB 1 +ATOM 23807 C CG . GLU M 1 124 ? 38.154 23.709 69.687 1.00 55.21 ? 124 GLU M CG 1 +ATOM 23808 C CD . GLU M 1 124 ? 37.939 22.684 68.611 1.00 58.94 ? 124 GLU M CD 1 +ATOM 23809 O OE1 . GLU M 1 124 ? 38.887 22.400 67.831 1.00 61.41 ? 124 GLU M OE1 1 +ATOM 23810 O OE2 . GLU M 1 124 ? 36.797 22.226 68.462 1.00 64.35 ? 124 GLU M OE2 1 +ATOM 23811 N N . GLY M 1 125 ? 38.905 27.743 69.641 1.00 94.26 ? 125 GLY M N 1 +ATOM 23812 C CA . GLY M 1 125 ? 38.231 29.014 69.787 1.00 83.47 ? 125 GLY M CA 1 +ATOM 23813 C C . GLY M 1 125 ? 38.255 29.801 68.475 1.00 66.61 ? 125 GLY M C 1 +ATOM 23814 O O . GLY M 1 125 ? 38.378 29.228 67.400 1.00 45.55 ? 125 GLY M O 1 +ATOM 23815 N N . SER M 1 126 ? 38.006 31.099 68.569 1.00 47.30 ? 126 SER M N 1 +ATOM 23816 C CA . SER M 1 126 ? 37.734 31.898 67.389 1.00 44.68 ? 126 SER M CA 1 +ATOM 23817 C C . SER M 1 126 ? 37.871 33.325 67.739 1.00 48.74 ? 126 SER M C 1 +ATOM 23818 O O . SER M 1 126 ? 37.591 33.733 68.881 1.00 93.78 ? 126 SER M O 1 +ATOM 23819 C CB . SER M 1 126 ? 36.300 31.690 66.859 1.00 52.02 ? 126 SER M CB 1 +ATOM 23820 O OG . SER M 1 126 ? 35.779 30.369 67.093 1.00 69.11 ? 126 SER M OG 1 +ATOM 23821 N N . ILE M 1 127 ? 38.361 34.108 66.812 1.00 59.64 ? 127 ILE M N 1 +ATOM 23822 C CA . ILE M 1 127 ? 38.288 35.558 66.983 1.00 83.62 ? 127 ILE M CA 1 +ATOM 23823 C C . ILE M 1 127 ? 36.878 35.982 66.631 1.00 93.88 ? 127 ILE M C 1 +ATOM 23824 O O . ILE M 1 127 ? 36.501 35.985 65.459 1.00 119.35 ? 127 ILE M O 1 +ATOM 23825 C CB . ILE M 1 127 ? 39.306 36.319 66.110 1.00 98.17 ? 127 ILE M CB 1 +ATOM 23826 C CG1 . ILE M 1 127 ? 40.743 36.011 66.577 1.00 106.00 ? 127 ILE M CG1 1 +ATOM 23827 C CG2 . ILE M 1 127 ? 39.027 37.822 66.141 1.00 62.52 ? 127 ILE M CG2 1 +ATOM 23828 C CD1 . ILE M 1 127 ? 41.776 36.050 65.465 1.00 116.60 ? 127 ILE M CD1 1 +ATOM 23829 N N . ILE M 1 128 ? 36.085 36.256 67.661 1.00 86.03 ? 128 ILE M N 1 +ATOM 23830 C CA . ILE M 1 128 ? 34.666 36.599 67.510 1.00 80.92 ? 128 ILE M CA 1 +ATOM 23831 C C . ILE M 1 128 ? 34.630 38.110 67.515 1.00 86.27 ? 128 ILE M C 1 +ATOM 23832 O O . ILE M 1 128 ? 34.881 38.773 68.513 1.00 116.86 ? 128 ILE M O 1 +ATOM 23833 C CB . ILE M 1 128 ? 33.812 35.997 68.642 1.00 85.64 ? 128 ILE M CB 1 +ATOM 23834 C CG1 . ILE M 1 128 ? 34.402 36.336 70.008 1.00 122.39 ? 128 ILE M CG1 1 +ATOM 23835 C CG2 . ILE M 1 128 ? 33.832 34.478 68.568 1.00 103.00 ? 128 ILE M CG2 1 +ATOM 23836 C CD1 . ILE M 1 128 ? 33.368 36.312 71.118 1.00 165.51 ? 128 ILE M CD1 1 +ATOM 23837 N N . GLY M 1 129 ? 34.578 38.667 66.323 1.00 100.67 ? 129 GLY M N 1 +ATOM 23838 C CA . GLY M 1 129 ? 34.311 40.100 66.196 1.00 80.59 ? 129 GLY M CA 1 +ATOM 23839 C C . GLY M 1 129 ? 35.445 41.106 66.325 1.00 79.58 ? 129 GLY M C 1 +ATOM 23840 O O . GLY M 1 129 ? 36.400 40.957 67.121 1.00 81.52 ? 129 GLY M O 1 +ATOM 23841 N N . TYR M 1 130 ? 35.436 42.025 65.374 1.00 85.75 ? 130 TYR M N 1 +ATOM 23842 C CA . TYR M 1 130 ? 36.254 43.215 65.444 1.00 84.74 ? 130 TYR M CA 1 +ATOM 23843 C C . TYR M 1 130 ? 35.354 44.313 64.925 1.00 100.73 ? 130 TYR M C 1 +ATOM 23844 O O . TYR M 1 130 ? 35.034 44.354 63.751 1.00 100.26 ? 130 TYR M O 1 +ATOM 23845 C CB . TYR M 1 130 ? 37.524 43.101 64.581 1.00 72.86 ? 130 TYR M CB 1 +ATOM 23846 C CG . TYR M 1 130 ? 38.363 44.358 64.516 1.00 56.88 ? 130 TYR M CG 1 +ATOM 23847 C CD1 . TYR M 1 130 ? 37.948 45.447 63.770 1.00 64.28 ? 130 TYR M CD1 1 +ATOM 23848 C CD2 . TYR M 1 130 ? 39.616 44.415 65.115 1.00 65.91 ? 130 TYR M CD2 1 +ATOM 23849 C CE1 . TYR M 1 130 ? 38.736 46.576 63.651 1.00 86.63 ? 130 TYR M CE1 1 +ATOM 23850 C CE2 . TYR M 1 130 ? 40.435 45.521 64.967 1.00 90.90 ? 130 TYR M CE2 1 +ATOM 23851 C CZ . TYR M 1 130 ? 39.982 46.608 64.257 1.00 100.37 ? 130 TYR M CZ 1 +ATOM 23852 O OH . TYR M 1 130 ? 40.780 47.723 64.161 1.00 115.10 ? 130 TYR M OH 1 +ATOM 23853 N N . GLU M 1 131 ? 34.858 45.129 65.832 1.00 112.58 ? 131 GLU M N 1 +ATOM 23854 C CA . GLU M 1 131 ? 34.124 46.324 65.440 1.00 129.29 ? 131 GLU M CA 1 +ATOM 23855 C C . GLU M 1 131 ? 35.083 47.503 65.455 1.00 101.29 ? 131 GLU M C 1 +ATOM 23856 O O . GLU M 1 131 ? 36.034 47.520 66.243 1.00 90.96 ? 131 GLU M O 1 +ATOM 23857 C CB . GLU M 1 131 ? 32.951 46.537 66.399 1.00 171.48 ? 131 GLU M CB 1 +ATOM 23858 C CG . GLU M 1 131 ? 31.958 47.622 66.003 1.00 128.74 ? 131 GLU M CG 1 +ATOM 23859 C CD . GLU M 1 131 ? 30.830 47.132 65.112 1.00 134.94 ? 131 GLU M CD 1 +ATOM 23860 O OE1 . GLU M 1 131 ? 30.495 45.917 65.151 1.00 172.01 ? 131 GLU M OE1 1 +ATOM 23861 O OE2 . GLU M 1 131 ? 30.334 47.946 64.307 1.00 119.75 ? 131 GLU M OE2 1 +ATOM 23862 N N . SER M 1 132 ? 34.880 48.437 64.539 1.00 87.63 ? 132 SER M N 1 +ATOM 23863 C CA . SER M 1 132 ? 35.847 49.501 64.331 1.00 93.98 ? 132 SER M CA 1 +ATOM 23864 C C . SER M 1 132 ? 35.242 50.878 64.607 1.00 113.34 ? 132 SER M C 1 +ATOM 23865 O O . SER M 1 132 ? 34.086 51.143 64.273 1.00 108.30 ? 132 SER M O 1 +ATOM 23866 C CB . SER M 1 132 ? 36.400 49.442 62.912 1.00 87.34 ? 132 SER M CB 1 +ATOM 23867 O OG . SER M 1 132 ? 35.976 50.555 62.152 1.00 84.54 ? 132 SER M OG 1 +ATOM 23868 N N . ASN M 1 133 ? 36.045 51.759 65.198 1.00 136.84 ? 133 ASN M N 1 +ATOM 23869 C CA . ASN M 1 133 ? 35.552 53.042 65.724 1.00 147.86 ? 133 ASN M CA 1 +ATOM 23870 C C . ASN M 1 133 ? 34.285 52.861 66.555 1.00 138.27 ? 133 ASN M C 1 +ATOM 23871 O O . ASN M 1 133 ? 33.252 53.465 66.275 1.00 114.02 ? 133 ASN M O 1 +ATOM 23872 C CB . ASN M 1 133 ? 35.302 54.043 64.599 1.00 130.09 ? 133 ASN M CB 1 +ATOM 23873 C CG . ASN M 1 133 ? 36.556 54.347 63.802 1.00 141.85 ? 133 ASN M CG 1 +ATOM 23874 O OD1 . ASN M 1 133 ? 37.681 54.269 64.310 1.00 145.75 ? 133 ASN M OD1 1 +ATOM 23875 N ND2 . ASN M 1 133 ? 36.366 54.649 62.535 1.00 155.12 ? 133 ASN M ND2 1 +ATOM 23876 N N . VAL M 1 134 ? 34.396 52.012 67.572 1.00 133.08 ? 134 VAL M N 1 +ATOM 23877 C CA . VAL M 1 134 ? 33.301 51.734 68.476 1.00 122.61 ? 134 VAL M CA 1 +ATOM 23878 C C . VAL M 1 134 ? 33.040 53.015 69.257 1.00 119.54 ? 134 VAL M C 1 +ATOM 23879 O O . VAL M 1 134 ? 31.889 53.351 69.568 1.00 106.00 ? 134 VAL M O 1 +ATOM 23880 C CB . VAL M 1 134 ? 33.642 50.551 69.420 1.00 131.07 ? 134 VAL M CB 1 +ATOM 23881 C CG1 . VAL M 1 134 ? 32.463 50.213 70.318 1.00 148.05 ? 134 VAL M CG1 1 +ATOM 23882 C CG2 . VAL M 1 134 ? 34.042 49.323 68.609 1.00 122.02 ? 134 VAL M CG2 1 +ATOM 23883 N N . LYS M 1 135 ? 34.116 53.742 69.560 1.00 127.24 ? 135 LYS M N 1 +ATOM 23884 C CA . LYS M 1 135 ? 33.999 55.135 69.999 1.00 125.38 ? 135 LYS M CA 1 +ATOM 23885 C C . LYS M 1 135 ? 35.016 56.022 69.306 1.00 127.19 ? 135 LYS M C 1 +ATOM 23886 O O . LYS M 1 135 ? 36.061 55.551 68.831 1.00 131.21 ? 135 LYS M O 1 +ATOM 23887 C CB . LYS M 1 135 ? 34.187 55.243 71.514 1.00 123.00 ? 135 LYS M CB 1 +ATOM 23888 C CG . LYS M 1 135 ? 33.126 54.500 72.313 1.00 126.06 ? 135 LYS M CG 1 +ATOM 23889 C CD . LYS M 1 135 ? 33.438 54.556 73.795 1.00 113.16 ? 135 LYS M CD 1 +ATOM 23890 C CE . LYS M 1 135 ? 32.401 53.810 74.605 1.00 110.44 ? 135 LYS M CE 1 +ATOM 23891 N NZ . LYS M 1 135 ? 32.424 54.278 76.013 1.00 118.98 ? 135 LYS M NZ 1 +ATOM 23892 N N . SER M 1 136 ? 34.718 57.317 69.281 1.00 138.36 ? 136 SER M N 1 +ATOM 23893 C CA . SER M 1 136 ? 35.624 58.293 68.681 1.00 153.42 ? 136 SER M CA 1 +ATOM 23894 C C . SER M 1 136 ? 35.297 59.719 69.108 1.00 138.97 ? 136 SER M C 1 +ATOM 23895 O O . SER M 1 136 ? 34.188 60.000 69.556 1.00 103.89 ? 136 SER M O 1 +ATOM 23896 C CB . SER M 1 136 ? 35.583 58.199 67.162 1.00 148.50 ? 136 SER M CB 1 +ATOM 23897 O OG . SER M 1 136 ? 35.278 59.453 66.579 1.00 113.25 ? 136 SER M OG 1 +ATOM 23898 N N . GLY M 1 137 ? 36.301 60.593 69.040 1.00 136.33 ? 137 GLY M N 1 +ATOM 23899 C CA . GLY M 1 137 ? 36.120 61.988 69.429 1.00 144.29 ? 137 GLY M CA 1 +ATOM 23900 C C . GLY M 1 137 ? 37.266 62.891 69.009 1.00 141.44 ? 137 GLY M C 1 +ATOM 23901 O O . GLY M 1 137 ? 38.273 62.429 68.478 1.00 93.35 ? 137 GLY M O 1 +ATOM 23902 N N . GLY M 1 138 ? 37.091 64.192 69.223 1.00 142.57 ? 138 GLY M N 1 +ATOM 23903 C CA . GLY M 1 138 ? 38.108 65.172 68.867 1.00 134.83 ? 138 GLY M CA 1 +ATOM 23904 C C . GLY M 1 138 ? 37.879 66.519 69.508 1.00 105.85 ? 138 GLY M C 1 +ATOM 23905 O O . GLY M 1 138 ? 36.741 66.931 69.706 1.00 95.88 ? 138 GLY M O 1 +ATOM 23906 N N . VAL M 1 139 ? 38.970 67.179 69.877 1.00 108.84 ? 139 VAL M N 1 +ATOM 23907 C CA . VAL M 1 139 ? 38.904 68.498 70.490 1.00 105.15 ? 139 VAL M CA 1 +ATOM 23908 C C . VAL M 1 139 ? 40.023 69.365 69.943 1.00 112.61 ? 139 VAL M C 1 +ATOM 23909 O O . VAL M 1 139 ? 41.203 69.000 70.014 1.00 104.13 ? 139 VAL M O 1 +ATOM 23910 C CB . VAL M 1 139 ? 39.035 68.449 72.032 1.00 102.86 ? 139 VAL M CB 1 +ATOM 23911 C CG1 . VAL M 1 139 ? 39.094 69.860 72.597 1.00 97.56 ? 139 VAL M CG1 1 +ATOM 23912 C CG2 . VAL M 1 139 ? 37.884 67.666 72.661 1.00 98.25 ? 139 VAL M CG2 1 +ATOM 23913 N N . GLY M 1 140 ? 39.657 70.538 69.440 1.00 131.21 ? 140 GLY M N 1 +ATOM 23914 C CA . GLY M 1 140 ? 40.633 71.460 68.866 1.00 134.45 ? 140 GLY M CA 1 +ATOM 23915 C C . GLY M 1 140 ? 40.256 72.915 69.015 1.00 116.56 ? 140 GLY M C 1 +ATOM 23916 O O . GLY M 1 140 ? 39.075 73.269 68.961 1.00 132.43 ? 140 GLY M O 1 +ATOM 23917 N N . ALA M 1 141 ? 41.267 73.769 69.128 1.00 101.31 ? 141 ALA M N 1 +ATOM 23918 C CA . ALA M 1 141 ? 41.036 75.206 69.123 1.00 107.78 ? 141 ALA M CA 1 +ATOM 23919 C C . ALA M 1 141 ? 42.137 75.958 68.383 1.00 118.06 ? 141 ALA M C 1 +ATOM 23920 O O . ALA M 1 141 ? 43.322 75.623 68.471 1.00 129.64 ? 141 ALA M O 1 +ATOM 23921 C CB . ALA M 1 141 ? 40.893 75.717 70.547 1.00 109.33 ? 141 ALA M CB 1 +ATOM 23922 N N . ARG M 1 142 ? 41.734 76.976 67.642 1.00 136.56 ? 142 ARG M N 1 +ATOM 23923 C CA . ARG M 1 142 ? 42.688 77.891 67.056 1.00 175.77 ? 142 ARG M CA 1 +ATOM 23924 C C . ARG M 1 142 ? 42.286 79.313 67.414 1.00 187.45 ? 142 ARG M C 1 +ATOM 23925 O O . ARG M 1 142 ? 41.098 79.627 67.508 1.00 221.53 ? 142 ARG M O 1 +ATOM 23926 C CB . ARG M 1 142 ? 42.775 77.707 65.536 1.00 184.55 ? 142 ARG M CB 1 +ATOM 23927 C CG . ARG M 1 142 ? 43.836 78.593 64.891 1.00 182.73 ? 142 ARG M CG 1 +ATOM 23928 C CD . ARG M 1 142 ? 44.619 77.864 63.826 1.00 165.86 ? 142 ARG M CD 1 +ATOM 23929 N NE . ARG M 1 142 ? 43.808 77.784 62.619 1.00 157.98 ? 142 ARG M NE 1 +ATOM 23930 C CZ . ARG M 1 142 ? 43.914 76.822 61.709 1.00 185.04 ? 142 ARG M CZ 1 +ATOM 23931 N NH1 . ARG M 1 142 ? 44.868 75.897 61.795 1.00 195.41 ? 142 ARG M NH1 1 +ATOM 23932 N NH2 . ARG M 1 142 ? 43.106 76.826 60.657 1.00 210.16 ? 142 ARG M NH2 1 +ATOM 23933 N N . TYR M 1 143 ? 43.288 80.161 67.625 1.00 176.52 ? 143 TYR M N 1 +ATOM 23934 C CA . TYR M 1 143 ? 43.075 81.518 68.105 1.00 168.16 ? 143 TYR M CA 1 +ATOM 23935 C C . TYR M 1 143 ? 43.870 82.501 67.239 1.00 147.76 ? 143 TYR M C 1 +ATOM 23936 O O . TYR M 1 143 ? 44.955 82.964 67.611 1.00 136.53 ? 143 TYR M O 1 +ATOM 23937 C CB . TYR M 1 143 ? 43.495 81.610 69.571 1.00 182.24 ? 143 TYR M CB 1 +ATOM 23938 C CG . TYR M 1 143 ? 43.172 82.918 70.229 1.00 201.44 ? 143 TYR M CG 1 +ATOM 23939 C CD1 . TYR M 1 143 ? 41.862 83.250 70.542 1.00 201.20 ? 143 TYR M CD1 1 +ATOM 23940 C CD2 . TYR M 1 143 ? 44.178 83.808 70.570 1.00 205.49 ? 143 TYR M CD2 1 +ATOM 23941 C CE1 . TYR M 1 143 ? 41.558 84.438 71.178 1.00 193.80 ? 143 TYR M CE1 1 +ATOM 23942 C CE2 . TYR M 1 143 ? 43.887 84.998 71.215 1.00 205.43 ? 143 TYR M CE2 1 +ATOM 23943 C CZ . TYR M 1 143 ? 42.574 85.309 71.511 1.00 191.56 ? 143 TYR M CZ 1 +ATOM 23944 O OH . TYR M 1 143 ? 42.277 86.496 72.133 1.00 184.99 ? 143 TYR M OH 1 +ATOM 23945 N N . GLY M 1 145 ? 45.792 82.837 65.382 1.00 167.06 ? 145 GLY M N 1 +ATOM 23946 C CA . GLY M 1 145 ? 47.013 82.401 64.712 1.00 172.51 ? 145 GLY M CA 1 +ATOM 23947 C C . GLY M 1 145 ? 47.588 81.080 65.204 1.00 195.71 ? 145 GLY M C 1 +ATOM 23948 O O . GLY M 1 145 ? 48.283 80.399 64.449 1.00 176.58 ? 145 GLY M O 1 +ATOM 23949 N N . ILE M 1 146 ? 47.296 80.711 66.457 1.00 224.33 ? 146 ILE M N 1 +ATOM 23950 C CA . ILE M 1 146 ? 47.922 79.544 67.115 1.00 179.48 ? 146 ILE M CA 1 +ATOM 23951 C C . ILE M 1 146 ? 46.846 78.490 67.393 1.00 142.85 ? 146 ILE M C 1 +ATOM 23952 O O . ILE M 1 146 ? 45.744 78.828 67.811 1.00 127.00 ? 146 ILE M O 1 +ATOM 23953 C CB . ILE M 1 146 ? 48.617 79.927 68.455 1.00 144.70 ? 146 ILE M CB 1 +ATOM 23954 C CG1 . ILE M 1 146 ? 49.333 81.284 68.329 1.00 146.10 ? 146 ILE M CG1 1 +ATOM 23955 C CG2 . ILE M 1 146 ? 49.603 78.851 68.877 1.00 104.87 ? 146 ILE M CG2 1 +ATOM 23956 C CD1 . ILE M 1 146 ? 48.524 82.467 68.836 1.00 131.53 ? 146 ILE M CD1 1 +ATOM 23957 N N . GLY M 1 147 ? 47.149 77.223 67.131 1.00 119.61 ? 147 GLY M N 1 +ATOM 23958 C CA . GLY M 1 147 ? 46.137 76.176 67.281 1.00 125.46 ? 147 GLY M CA 1 +ATOM 23959 C C . GLY M 1 147 ? 46.648 74.792 67.634 1.00 124.45 ? 147 GLY M C 1 +ATOM 23960 O O . GLY M 1 147 ? 47.796 74.450 67.356 1.00 112.91 ? 147 GLY M O 1 +ATOM 23961 N N . ALA M 1 148 ? 45.775 73.997 68.241 1.00 128.98 ? 148 ALA M N 1 +ATOM 23962 C CA . ALA M 1 148 ? 46.067 72.601 68.494 1.00 120.74 ? 148 ALA M CA 1 +ATOM 23963 C C . ALA M 1 148 ? 44.784 71.779 68.454 1.00 114.48 ? 148 ALA M C 1 +ATOM 23964 O O . ALA M 1 148 ? 43.673 72.318 68.466 1.00 82.96 ? 148 ALA M O 1 +ATOM 23965 C CB . ALA M 1 148 ? 46.773 72.436 69.835 1.00 109.45 ? 148 ALA M CB 1 +ATOM 23966 N N . ASP M 1 149 ? 44.951 70.466 68.387 1.00 129.72 ? 149 ASP M N 1 +ATOM 23967 C CA . ASP M 1 149 ? 43.806 69.560 68.381 1.00 152.58 ? 149 ASP M CA 1 +ATOM 23968 C C . ASP M 1 149 ? 44.246 68.122 68.632 1.00 152.16 ? 149 ASP M C 1 +ATOM 23969 O O . ASP M 1 149 ? 45.358 67.735 68.261 1.00 153.38 ? 149 ASP M O 1 +ATOM 23970 C CB . ASP M 1 149 ? 43.036 69.661 67.054 1.00 166.13 ? 149 ASP M CB 1 +ATOM 23971 C CG . ASP M 1 149 ? 43.675 68.873 65.954 1.00 168.88 ? 149 ASP M CG 1 +ATOM 23972 O OD1 . ASP M 1 149 ? 44.710 69.336 65.423 1.00 177.67 ? 149 ASP M OD1 1 +ATOM 23973 O OD2 . ASP M 1 149 ? 43.145 67.801 65.601 1.00 152.69 ? 149 ASP M OD2 1 +ATOM 23974 N N . THR M 1 150 ? 43.387 67.347 69.282 1.00 139.61 ? 150 THR M N 1 +ATOM 23975 C CA . THR M 1 150 ? 43.564 65.905 69.319 1.00 128.74 ? 150 THR M CA 1 +ATOM 23976 C C . THR M 1 150 ? 42.321 65.221 68.802 1.00 107.22 ? 150 THR M C 1 +ATOM 23977 O O . THR M 1 150 ? 41.229 65.794 68.765 1.00 112.60 ? 150 THR M O 1 +ATOM 23978 C CB . THR M 1 150 ? 43.846 65.370 70.731 1.00 142.76 ? 150 THR M CB 1 +ATOM 23979 O OG1 . THR M 1 150 ? 42.757 65.712 71.597 1.00 176.61 ? 150 THR M OG1 1 +ATOM 23980 C CG2 . THR M 1 150 ? 45.141 65.935 71.279 1.00 137.66 ? 150 THR M CG2 1 +ATOM 23981 N N . GLN M 1 151 ? 42.515 63.998 68.346 1.00 112.32 ? 151 GLN M N 1 +ATOM 23982 C CA . GLN M 1 151 ? 41.433 63.166 67.871 1.00 115.02 ? 151 GLN M CA 1 +ATOM 23983 C C . GLN M 1 151 ? 41.707 61.754 68.282 1.00 118.45 ? 151 GLN M C 1 +ATOM 23984 O O . GLN M 1 151 ? 42.858 61.345 68.290 1.00 133.70 ? 151 GLN M O 1 +ATOM 23985 C CB . GLN M 1 151 ? 41.415 63.266 66.362 1.00 128.22 ? 151 GLN M CB 1 +ATOM 23986 C CG . GLN M 1 151 ? 40.293 62.614 65.592 1.00 138.34 ? 151 GLN M CG 1 +ATOM 23987 C CD . GLN M 1 151 ? 40.334 63.081 64.153 1.00 148.24 ? 151 GLN M CD 1 +ATOM 23988 O OE1 . GLN M 1 151 ? 41.416 63.339 63.622 1.00 111.95 ? 151 GLN M OE1 1 +ATOM 23989 N NE2 . GLN M 1 151 ? 39.167 63.331 63.567 1.00 176.53 ? 151 GLN M NE2 1 +ATOM 23990 N N . TYR M 1 152 ? 40.672 61.015 68.648 1.00 102.32 ? 152 TYR M N 1 +ATOM 23991 C CA . TYR M 1 152 ? 40.870 59.641 69.075 1.00 96.18 ? 152 TYR M CA 1 +ATOM 23992 C C . TYR M 1 152 ? 39.796 58.722 68.558 1.00 109.32 ? 152 TYR M C 1 +ATOM 23993 O O . TYR M 1 152 ? 38.654 59.129 68.359 1.00 99.03 ? 152 TYR M O 1 +ATOM 23994 C CB . TYR M 1 152 ? 40.943 59.554 70.595 1.00 87.32 ? 152 TYR M CB 1 +ATOM 23995 C CG . TYR M 1 152 ? 39.727 58.991 71.300 1.00 78.47 ? 152 TYR M CG 1 +ATOM 23996 C CD1 . TYR M 1 152 ? 38.506 59.643 71.265 1.00 74.66 ? 152 TYR M CD1 1 +ATOM 23997 C CD2 . TYR M 1 152 ? 39.845 57.879 72.110 1.00 89.46 ? 152 TYR M CD2 1 +ATOM 23998 C CE1 . TYR M 1 152 ? 37.412 59.160 71.970 1.00 87.62 ? 152 TYR M CE1 1 +ATOM 23999 C CE2 . TYR M 1 152 ? 38.771 57.404 72.843 1.00 102.08 ? 152 TYR M CE2 1 +ATOM 24000 C CZ . TYR M 1 152 ? 37.552 58.038 72.759 1.00 99.37 ? 152 TYR M CZ 1 +ATOM 24001 O OH . TYR M 1 152 ? 36.482 57.560 73.488 1.00 126.87 ? 152 TYR M OH 1 +ATOM 24002 N N . GLN M 1 153 ? 40.188 57.485 68.294 1.00 128.16 ? 153 GLN M N 1 +ATOM 24003 C CA . GLN M 1 153 ? 39.228 56.455 67.961 1.00 137.57 ? 153 GLN M CA 1 +ATOM 24004 C C . GLN M 1 153 ? 39.582 55.194 68.722 1.00 115.29 ? 153 GLN M C 1 +ATOM 24005 O O . GLN M 1 153 ? 40.751 54.957 69.045 1.00 125.54 ? 153 GLN M O 1 +ATOM 24006 C CB . GLN M 1 153 ? 39.222 56.207 66.442 1.00 191.55 ? 153 GLN M CB 1 +ATOM 24007 C CG . GLN M 1 153 ? 38.719 57.386 65.591 1.00 222.09 ? 153 GLN M CG 1 +ATOM 24008 C CD . GLN M 1 153 ? 38.842 57.097 64.080 1.00 261.18 ? 153 GLN M CD 1 +ATOM 24009 O OE1 . GLN M 1 153 ? 39.630 56.241 63.655 1.00 265.44 ? 153 GLN M OE1 1 +ATOM 24010 N NE2 . GLN M 1 153 ? 38.078 57.825 63.268 1.00 283.50 ? 153 GLN M NE2 1 +ATOM 24011 N N . LEU M 1 154 ? 38.589 54.352 68.965 1.00 91.79 ? 154 LEU M N 1 +ATOM 24012 C CA . LEU M 1 154 ? 38.870 53.031 69.518 1.00 93.39 ? 154 LEU M CA 1 +ATOM 24013 C C . LEU M 1 154 ? 37.965 51.925 68.994 1.00 91.52 ? 154 LEU M C 1 +ATOM 24014 O O . LEU M 1 154 ? 36.764 52.145 68.723 1.00 74.40 ? 154 LEU M O 1 +ATOM 24015 C CB . LEU M 1 154 ? 38.806 53.066 71.038 1.00 83.95 ? 154 LEU M CB 1 +ATOM 24016 C CG . LEU M 1 154 ? 37.405 53.211 71.632 1.00 101.14 ? 154 LEU M CG 1 +ATOM 24017 C CD1 . LEU M 1 154 ? 36.809 51.867 72.000 1.00 84.75 ? 154 LEU M CD1 1 +ATOM 24018 C CD2 . LEU M 1 154 ? 37.475 54.133 72.840 1.00 147.67 ? 154 LEU M CD2 1 +ATOM 24019 N N . ASP M 1 155 ? 38.561 50.730 68.906 1.00 91.78 ? 155 ASP M N 1 +ATOM 24020 C CA . ASP M 1 155 ? 37.983 49.574 68.224 1.00 94.88 ? 155 ASP M CA 1 +ATOM 24021 C C . ASP M 1 155 ? 37.866 48.440 69.225 1.00 92.58 ? 155 ASP M C 1 +ATOM 24022 O O . ASP M 1 155 ? 38.538 48.453 70.257 1.00 77.07 ? 155 ASP M O 1 +ATOM 24023 C CB . ASP M 1 155 ? 38.881 49.142 67.054 1.00 95.65 ? 155 ASP M CB 1 +ATOM 24024 C CG . ASP M 1 155 ? 39.304 50.313 66.180 1.00 126.11 ? 155 ASP M CG 1 +ATOM 24025 O OD1 . ASP M 1 155 ? 40.238 51.047 66.574 1.00 139.80 ? 155 ASP M OD1 1 +ATOM 24026 O OD2 . ASP M 1 155 ? 38.700 50.510 65.102 1.00 121.83 ? 155 ASP M OD2 1 +ATOM 24027 N N . GLN M 1 156 ? 37.021 47.453 68.928 1.00 86.65 ? 156 GLN M N 1 +ATOM 24028 C CA . GLN M 1 156 ? 36.878 46.291 69.811 1.00 85.21 ? 156 GLN M CA 1 +ATOM 24029 C C . GLN M 1 156 ? 37.394 44.997 69.169 1.00 81.87 ? 156 GLN M C 1 +ATOM 24030 O O . GLN M 1 156 ? 37.401 44.868 67.950 1.00 115.19 ? 156 GLN M O 1 +ATOM 24031 C CB . GLN M 1 156 ? 35.417 46.160 70.238 1.00 84.06 ? 156 GLN M CB 1 +ATOM 24032 C CG . GLN M 1 156 ? 35.187 45.191 71.389 1.00 87.94 ? 156 GLN M CG 1 +ATOM 24033 C CD . GLN M 1 156 ? 33.879 45.454 72.121 1.00 93.96 ? 156 GLN M CD 1 +ATOM 24034 O OE1 . GLN M 1 156 ? 33.025 46.237 71.658 1.00 94.14 ? 156 GLN M OE1 1 +ATOM 24035 N NE2 . GLN M 1 156 ? 33.701 44.779 73.254 1.00 72.27 ? 156 GLN M NE2 1 +ATOM 24036 N N . ILE M 1 157 ? 37.784 44.034 69.995 1.00 67.46 ? 157 ILE M N 1 +ATOM 24037 C CA . ILE M 1 157 ? 38.148 42.692 69.518 1.00 62.49 ? 157 ILE M CA 1 +ATOM 24038 C C . ILE M 1 157 ? 37.825 41.645 70.598 1.00 51.69 ? 157 ILE M C 1 +ATOM 24039 O O . ILE M 1 157 ? 37.910 41.937 71.792 1.00 58.18 ? 157 ILE M O 1 +ATOM 24040 C CB . ILE M 1 157 ? 39.639 42.654 69.187 1.00 59.38 ? 157 ILE M CB 1 +ATOM 24041 C CG1 . ILE M 1 157 ? 39.936 41.558 68.189 1.00 65.48 ? 157 ILE M CG1 1 +ATOM 24042 C CG2 . ILE M 1 157 ? 40.454 42.440 70.447 1.00 58.50 ? 157 ILE M CG2 1 +ATOM 24043 C CD1 . ILE M 1 157 ? 41.364 41.564 67.659 1.00 60.87 ? 157 ILE M CD1 1 +ATOM 24044 N N . ALA M 1 158 ? 37.255 40.528 70.195 1.00 48.38 ? 158 ALA M N 1 +ATOM 24045 C CA . ALA M 1 158 ? 36.802 39.569 71.175 1.00 64.49 ? 158 ALA M CA 1 +ATOM 24046 C C . ALA M 1 158 ? 37.245 38.199 70.754 1.00 87.15 ? 158 ALA M C 1 +ATOM 24047 O O . ALA M 1 158 ? 37.422 37.910 69.567 1.00 62.78 ? 158 ALA M O 1 +ATOM 24048 C CB . ALA M 1 158 ? 35.288 39.600 71.373 1.00 62.37 ? 158 ALA M CB 1 +ATOM 24049 N N . VAL M 1 159 ? 37.458 37.353 71.754 1.00 97.19 ? 159 VAL M N 1 +ATOM 24050 C CA . VAL M 1 159 ? 38.012 36.035 71.523 1.00 99.20 ? 159 VAL M CA 1 +ATOM 24051 C C . VAL M 1 159 ? 37.256 35.013 72.364 1.00 83.71 ? 159 VAL M C 1 +ATOM 24052 O O . VAL M 1 159 ? 37.127 35.161 73.569 1.00 112.16 ? 159 VAL M O 1 +ATOM 24053 C CB . VAL M 1 159 ? 39.535 36.011 71.823 1.00 100.75 ? 159 VAL M CB 1 +ATOM 24054 C CG1 . VAL M 1 159 ? 40.033 34.598 72.056 1.00 94.11 ? 159 VAL M CG1 1 +ATOM 24055 C CG2 . VAL M 1 159 ? 40.315 36.645 70.680 1.00 97.25 ? 159 VAL M CG2 1 +ATOM 24056 N N . ASN M 1 160 ? 36.791 33.961 71.707 1.00 69.16 ? 160 ASN M N 1 +ATOM 24057 C CA . ASN M 1 160 ? 36.324 32.763 72.374 1.00 73.81 ? 160 ASN M CA 1 +ATOM 24058 C C . ASN M 1 160 ? 37.476 31.732 72.471 1.00 83.27 ? 160 ASN M C 1 +ATOM 24059 O O . ASN M 1 160 ? 38.175 31.459 71.496 1.00 72.11 ? 160 ASN M O 1 +ATOM 24060 C CB . ASN M 1 160 ? 35.161 32.187 71.568 1.00 72.64 ? 160 ASN M CB 1 +ATOM 24061 C CG . ASN M 1 160 ? 34.611 30.875 72.118 1.00 89.51 ? 160 ASN M CG 1 +ATOM 24062 O OD1 . ASN M 1 160 ? 35.351 29.947 72.473 1.00 75.21 ? 160 ASN M OD1 1 +ATOM 24063 N ND2 . ASN M 1 160 ? 33.287 30.785 72.155 1.00 92.83 ? 160 ASN M ND2 1 +ATOM 24064 N N . LEU M 1 161 ? 37.696 31.207 73.671 1.00 88.23 ? 161 LEU M N 1 +ATOM 24065 C CA . LEU M 1 161 ? 38.470 29.973 73.853 1.00 77.87 ? 161 LEU M CA 1 +ATOM 24066 C C . LEU M 1 161 ? 37.634 28.969 74.620 1.00 79.50 ? 161 LEU M C 1 +ATOM 24067 O O . LEU M 1 161 ? 36.785 29.341 75.437 1.00 143.19 ? 161 LEU M O 1 +ATOM 24068 C CB . LEU M 1 161 ? 39.740 30.243 74.636 1.00 73.12 ? 161 LEU M CB 1 +ATOM 24069 C CG . LEU M 1 161 ? 40.747 31.143 73.957 1.00 94.12 ? 161 LEU M CG 1 +ATOM 24070 C CD1 . LEU M 1 161 ? 41.873 31.476 74.924 1.00 88.51 ? 161 LEU M CD1 1 +ATOM 24071 C CD2 . LEU M 1 161 ? 41.271 30.471 72.699 1.00 110.76 ? 161 LEU M CD2 1 +ATOM 24072 N N . ARG M 1 162 ? 37.819 27.698 74.342 1.00 69.70 ? 162 ARG M N 1 +ATOM 24073 C CA . ARG M 1 162 ? 36.987 26.693 75.001 1.00 60.45 ? 162 ARG M CA 1 +ATOM 24074 C C . ARG M 1 162 ? 37.617 25.336 75.072 1.00 55.94 ? 162 ARG M C 1 +ATOM 24075 O O . ARG M 1 162 ? 38.187 24.825 74.089 1.00 115.22 ? 162 ARG M O 1 +ATOM 24076 C CB . ARG M 1 162 ? 35.594 26.597 74.358 1.00 63.87 ? 162 ARG M CB 1 +ATOM 24077 C CG . ARG M 1 162 ? 35.511 26.149 72.903 1.00 78.56 ? 162 ARG M CG 1 +ATOM 24078 C CD . ARG M 1 162 ? 34.080 25.696 72.568 1.00 84.63 ? 162 ARG M CD 1 +ATOM 24079 N NE . ARG M 1 162 ? 33.898 25.046 71.265 1.00 84.25 ? 162 ARG M NE 1 +ATOM 24080 C CZ . ARG M 1 162 ? 33.823 25.711 70.114 1.00 98.80 ? 162 ARG M CZ 1 +ATOM 24081 N NH1 . ARG M 1 162 ? 33.982 27.041 70.068 1.00 100.67 ? 162 ARG M NH1 1 +ATOM 24082 N NH2 . ARG M 1 162 ? 33.655 25.038 68.988 1.00 102.93 ? 162 ARG M NH2 1 +ATOM 24083 N N . VAL M 1 163 ? 37.621 24.799 76.267 1.00 54.26 ? 163 VAL M N 1 +ATOM 24084 C CA . VAL M 1 163 ? 38.198 23.487 76.534 1.00 71.34 ? 163 VAL M CA 1 +ATOM 24085 C C . VAL M 1 163 ? 37.184 22.421 76.198 1.00 57.12 ? 163 VAL M C 1 +ATOM 24086 O O . VAL M 1 163 ? 36.120 22.368 76.829 1.00 99.24 ? 163 VAL M O 1 +ATOM 24087 C CB . VAL M 1 163 ? 38.572 23.313 78.037 1.00 86.25 ? 163 VAL M CB 1 +ATOM 24088 C CG1 . VAL M 1 163 ? 39.131 21.897 78.289 1.00 82.30 ? 163 VAL M CG1 1 +ATOM 24089 C CG2 . VAL M 1 163 ? 39.533 24.422 78.494 1.00 75.65 ? 163 VAL M CG2 1 +ATOM 24090 N N . VAL M 1 164 ? 37.604 21.476 75.377 1.00 40.22 ? 164 VAL M N 1 +ATOM 24091 C CA . VAL M 1 164 ? 36.781 20.341 75.004 1.00 42.14 ? 164 VAL M CA 1 +ATOM 24092 C C . VAL M 1 164 ? 37.413 19.090 75.509 1.00 43.02 ? 164 VAL M C 1 +ATOM 24093 O O . VAL M 1 164 ? 38.607 18.896 75.358 1.00 51.17 ? 164 VAL M O 1 +ATOM 24094 C CB . VAL M 1 164 ? 36.661 20.206 73.481 1.00 48.35 ? 164 VAL M CB 1 +ATOM 24095 C CG1 . VAL M 1 164 ? 35.822 19.010 73.097 1.00 36.29 ? 164 VAL M CG1 1 +ATOM 24096 C CG2 . VAL M 1 164 ? 36.044 21.481 72.912 1.00 74.50 ? 164 VAL M CG2 1 +ATOM 24097 N N . ASN M 1 165 ? 36.594 18.240 76.106 1.00 60.24 ? 165 ASN M N 1 +ATOM 24098 C CA . ASN M 1 165 ? 37.058 16.967 76.599 1.00 72.88 ? 165 ASN M CA 1 +ATOM 24099 C C . ASN M 1 165 ? 37.077 15.921 75.469 1.00 101.80 ? 165 ASN M C 1 +ATOM 24100 O O . ASN M 1 165 ? 36.033 15.574 74.903 1.00 78.72 ? 165 ASN M O 1 +ATOM 24101 C CB . ASN M 1 165 ? 36.186 16.460 77.731 1.00 69.19 ? 165 ASN M CB 1 +ATOM 24102 C CG . ASN M 1 165 ? 36.814 15.281 78.442 1.00 94.73 ? 165 ASN M CG 1 +ATOM 24103 O OD1 . ASN M 1 165 ? 37.947 14.894 78.155 1.00 94.21 ? 165 ASN M OD1 1 +ATOM 24104 N ND2 . ASN M 1 165 ? 36.017 14.594 79.232 1.00 135.23 ? 165 ASN M ND2 1 +ATOM 24105 N N . VAL M 1 166 ? 38.278 15.411 75.165 1.00 104.27 ? 166 VAL M N 1 +ATOM 24106 C CA . VAL M 1 166 ? 38.486 14.445 74.077 1.00 74.42 ? 166 VAL M CA 1 +ATOM 24107 C C . VAL M 1 166 ? 37.662 13.210 74.315 1.00 67.40 ? 166 VAL M C 1 +ATOM 24108 O O . VAL M 1 166 ? 37.092 12.664 73.403 1.00 58.62 ? 166 VAL M O 1 +ATOM 24109 C CB . VAL M 1 166 ? 39.985 14.062 73.952 1.00 70.37 ? 166 VAL M CB 1 +ATOM 24110 C CG1 . VAL M 1 166 ? 40.172 12.690 73.306 1.00 58.70 ? 166 VAL M CG1 1 +ATOM 24111 C CG2 . VAL M 1 166 ? 40.731 15.172 73.203 1.00 82.66 ? 166 VAL M CG2 1 +ATOM 24112 N N . SER M 1 167 ? 37.594 12.801 75.574 1.00 74.51 ? 167 SER M N 1 +ATOM 24113 C CA . SER M 1 167 ? 37.004 11.536 75.927 1.00 83.23 ? 167 SER M CA 1 +ATOM 24114 C C . SER M 1 167 ? 35.481 11.536 75.760 1.00 88.22 ? 167 SER M C 1 +ATOM 24115 O O . SER M 1 167 ? 34.866 10.461 75.809 1.00 78.50 ? 167 SER M O 1 +ATOM 24116 C CB . SER M 1 167 ? 37.409 11.168 77.359 1.00 96.67 ? 167 SER M CB 1 +ATOM 24117 O OG . SER M 1 167 ? 38.802 11.379 77.569 1.00 119.85 ? 167 SER M OG 1 +ATOM 24118 N N . THR M 1 168 ? 34.873 12.721 75.605 1.00 79.71 ? 168 THR M N 1 +ATOM 24119 C CA . THR M 1 168 ? 33.411 12.811 75.559 1.00 74.58 ? 168 THR M CA 1 +ATOM 24120 C C . THR M 1 168 ? 32.904 13.768 74.532 1.00 59.91 ? 168 THR M C 1 +ATOM 24121 O O . THR M 1 168 ? 31.817 13.577 73.929 1.00 74.97 ? 168 THR M O 1 +ATOM 24122 C CB . THR M 1 168 ? 32.810 13.247 76.912 1.00 83.90 ? 168 THR M CB 1 +ATOM 24123 O OG1 . THR M 1 168 ? 33.471 14.423 77.379 1.00 74.96 ? 168 THR M OG1 1 +ATOM 24124 C CG2 . THR M 1 168 ? 32.949 12.130 77.957 1.00 101.67 ? 168 THR M CG2 1 +ATOM 24125 N N . GLY M 1 169 ? 33.622 14.855 74.364 1.00 50.25 ? 169 GLY M N 1 +ATOM 24126 C CA . GLY M 1 169 ? 33.101 15.892 73.485 1.00 77.51 ? 169 GLY M CA 1 +ATOM 24127 C C . GLY M 1 169 ? 32.340 16.961 74.239 1.00 65.34 ? 169 GLY M C 1 +ATOM 24128 O O . GLY M 1 169 ? 32.049 18.013 73.688 1.00 56.70 ? 169 GLY M O 1 +ATOM 24129 N N . GLU M 1 170 ? 32.057 16.699 75.506 1.00 69.65 ? 170 GLU M N 1 +ATOM 24130 C CA . GLU M 1 170 ? 31.594 17.748 76.407 1.00 68.38 ? 170 GLU M CA 1 +ATOM 24131 C C . GLU M 1 170 ? 32.565 18.894 76.351 1.00 54.01 ? 170 GLU M C 1 +ATOM 24132 O O . GLU M 1 170 ? 33.788 18.716 76.486 1.00 65.80 ? 170 GLU M O 1 +ATOM 24133 C CB . GLU M 1 170 ? 31.520 17.242 77.866 1.00 101.19 ? 170 GLU M CB 1 +ATOM 24134 C CG . GLU M 1 170 ? 30.312 16.357 78.161 1.00 125.12 ? 170 GLU M CG 1 +ATOM 24135 C CD . GLU M 1 170 ? 30.579 15.226 79.153 1.00 137.49 ? 170 GLU M CD 1 +ATOM 24136 O OE1 . GLU M 1 170 ? 31.757 14.955 79.458 1.00 125.34 ? 170 GLU M OE1 1 +ATOM 24137 O OE2 . GLU M 1 170 ? 29.613 14.531 79.544 1.00 148.16 ? 170 GLU M OE2 1 +ATOM 24138 N N . ILE M 1 171 ? 32.051 20.080 76.132 1.00 45.55 ? 171 ILE M N 1 +ATOM 24139 C CA . ILE M 1 171 ? 32.864 21.262 76.346 1.00 59.91 ? 171 ILE M CA 1 +ATOM 24140 C C . ILE M 1 171 ? 32.992 21.493 77.840 1.00 80.63 ? 171 ILE M C 1 +ATOM 24141 O O . ILE M 1 171 ? 31.992 21.469 78.561 1.00 142.08 ? 171 ILE M O 1 +ATOM 24142 C CB . ILE M 1 171 ? 32.213 22.488 75.712 1.00 75.53 ? 171 ILE M CB 1 +ATOM 24143 C CG1 . ILE M 1 171 ? 32.332 22.391 74.181 1.00 105.17 ? 171 ILE M CG1 1 +ATOM 24144 C CG2 . ILE M 1 171 ? 32.870 23.754 76.238 1.00 74.63 ? 171 ILE M CG2 1 +ATOM 24145 C CD1 . ILE M 1 171 ? 31.408 23.325 73.440 1.00 97.90 ? 171 ILE M CD1 1 +ATOM 24146 N N . LEU M 1 172 ? 34.220 21.603 78.336 1.00 82.75 ? 172 LEU M N 1 +ATOM 24147 C CA . LEU M 1 172 ? 34.438 21.664 79.786 1.00 70.46 ? 172 LEU M CA 1 +ATOM 24148 C C . LEU M 1 172 ? 34.472 23.100 80.266 1.00 63.41 ? 172 LEU M C 1 +ATOM 24149 O O . LEU M 1 172 ? 34.466 23.371 81.476 1.00 114.53 ? 172 LEU M O 1 +ATOM 24150 C CB . LEU M 1 172 ? 35.711 20.889 80.210 1.00 62.48 ? 172 LEU M CB 1 +ATOM 24151 C CG . LEU M 1 172 ? 35.598 19.336 80.113 1.00 72.49 ? 172 LEU M CG 1 +ATOM 24152 C CD1 . LEU M 1 172 ? 36.768 18.498 80.637 1.00 64.76 ? 172 LEU M CD1 1 +ATOM 24153 C CD2 . LEU M 1 172 ? 34.272 18.796 80.647 1.00 80.93 ? 172 LEU M CD2 1 +ATOM 24154 N N . SER M 1 173 ? 34.584 24.014 79.322 1.00 55.74 ? 173 SER M N 1 +ATOM 24155 C CA . SER M 1 173 ? 34.705 25.408 79.642 1.00 73.25 ? 173 SER M CA 1 +ATOM 24156 C C . SER M 1 173 ? 34.652 26.252 78.382 1.00 94.44 ? 173 SER M C 1 +ATOM 24157 O O . SER M 1 173 ? 35.410 26.036 77.433 1.00 130.42 ? 173 SER M O 1 +ATOM 24158 C CB . SER M 1 173 ? 36.032 25.705 80.373 1.00 100.41 ? 173 SER M CB 1 +ATOM 24159 O OG . SER M 1 173 ? 36.285 27.104 80.399 1.00 168.01 ? 173 SER M OG 1 +ATOM 24160 N N . SER M 1 174 ? 33.828 27.292 78.406 1.00 115.28 ? 174 SER M N 1 +ATOM 24161 C CA . SER M 1 174 ? 33.857 28.327 77.358 1.00 110.42 ? 174 SER M CA 1 +ATOM 24162 C C . SER M 1 174 ? 34.059 29.677 77.996 1.00 80.24 ? 174 SER M C 1 +ATOM 24163 O O . SER M 1 174 ? 33.473 29.973 79.036 1.00 80.36 ? 174 SER M O 1 +ATOM 24164 C CB . SER M 1 174 ? 32.546 28.344 76.547 1.00 130.29 ? 174 SER M CB 1 +ATOM 24165 O OG . SER M 1 174 ? 32.641 29.159 75.385 1.00 115.42 ? 174 SER M OG 1 +ATOM 24166 N N . VAL M 1 175 ? 34.909 30.485 77.384 1.00 77.08 ? 175 VAL M N 1 +ATOM 24167 C CA . VAL M 1 175 ? 35.197 31.825 77.896 1.00 103.84 ? 175 VAL M CA 1 +ATOM 24168 C C . VAL M 1 175 ? 35.226 32.839 76.766 1.00 91.42 ? 175 VAL M C 1 +ATOM 24169 O O . VAL M 1 175 ? 35.739 32.543 75.678 1.00 133.24 ? 175 VAL M O 1 +ATOM 24170 C CB . VAL M 1 175 ? 36.536 31.880 78.690 1.00 117.67 ? 175 VAL M CB 1 +ATOM 24171 C CG1 . VAL M 1 175 ? 36.463 30.994 79.924 1.00 131.91 ? 175 VAL M CG1 1 +ATOM 24172 C CG2 . VAL M 1 175 ? 37.714 31.444 77.840 1.00 135.96 ? 175 VAL M CG2 1 +ATOM 24173 N N . ASN M 1 176 ? 34.792 34.053 77.074 1.00 75.39 ? 176 ASN M N 1 +ATOM 24174 C CA . ASN M 1 176 ? 34.646 35.088 76.076 1.00 84.28 ? 176 ASN M CA 1 +ATOM 24175 C C . ASN M 1 176 ? 35.355 36.367 76.495 1.00 89.52 ? 176 ASN M C 1 +ATOM 24176 O O . ASN M 1 176 ? 34.749 37.214 77.144 1.00 129.40 ? 176 ASN M O 1 +ATOM 24177 C CB . ASN M 1 176 ? 33.153 35.353 75.882 1.00 79.99 ? 176 ASN M CB 1 +ATOM 24178 C CG . ASN M 1 176 ? 32.559 34.599 74.704 1.00 97.12 ? 176 ASN M CG 1 +ATOM 24179 O OD1 . ASN M 1 176 ? 31.417 34.890 74.216 1.00 146.16 ? 176 ASN M OD1 1 +ATOM 24180 N ND2 . ASN M 1 176 ? 33.334 33.659 74.181 1.00 95.59 ? 176 ASN M ND2 1 +ATOM 24181 N N . THR M 1 177 ? 36.600 36.565 76.054 1.00 88.07 ? 177 THR M N 1 +ATOM 24182 C CA . THR M 1 177 ? 37.356 37.771 76.410 1.00 88.41 ? 177 THR M CA 1 +ATOM 24183 C C . THR M 1 177 ? 37.275 38.869 75.340 1.00 83.58 ? 177 THR M C 1 +ATOM 24184 O O . THR M 1 177 ? 36.929 38.607 74.194 1.00 70.64 ? 177 THR M O 1 +ATOM 24185 C CB . THR M 1 177 ? 38.837 37.455 76.672 1.00 91.41 ? 177 THR M CB 1 +ATOM 24186 O OG1 . THR M 1 177 ? 39.479 37.132 75.436 1.00 113.19 ? 177 THR M OG1 1 +ATOM 24187 C CG2 . THR M 1 177 ? 38.980 36.286 77.642 1.00 80.46 ? 177 THR M CG2 1 +ATOM 24188 N N . SER M 1 178 ? 37.564 40.101 75.747 1.00 83.43 ? 178 SER M N 1 +ATOM 24189 C CA . SER M 1 178 ? 37.426 41.257 74.871 1.00 93.17 ? 178 SER M CA 1 +ATOM 24190 C C . SER M 1 178 ? 38.483 42.294 75.184 1.00 83.58 ? 178 SER M C 1 +ATOM 24191 O O . SER M 1 178 ? 38.948 42.414 76.322 1.00 107.06 ? 178 SER M O 1 +ATOM 24192 C CB . SER M 1 178 ? 36.033 41.892 75.002 1.00 117.72 ? 178 SER M CB 1 +ATOM 24193 O OG . SER M 1 178 ? 35.984 43.191 74.404 1.00 129.92 ? 178 SER M OG 1 +ATOM 24194 N N . LYS M 1 179 ? 38.814 43.103 74.188 1.00 78.46 ? 179 LYS M N 1 +ATOM 24195 C CA . LYS M 1 179 ? 39.876 44.070 74.351 1.00 89.54 ? 179 LYS M CA 1 +ATOM 24196 C C . LYS M 1 179 ? 39.695 45.243 73.391 1.00 118.20 ? 179 LYS M C 1 +ATOM 24197 O O . LYS M 1 179 ? 39.222 45.087 72.265 1.00 149.27 ? 179 LYS M O 1 +ATOM 24198 C CB . LYS M 1 179 ? 41.209 43.369 74.117 1.00 88.81 ? 179 LYS M CB 1 +ATOM 24199 C CG . LYS M 1 179 ? 42.339 43.855 75.004 1.00 113.94 ? 179 LYS M CG 1 +ATOM 24200 C CD . LYS M 1 179 ? 43.140 44.923 74.294 1.00 122.36 ? 179 LYS M CD 1 +ATOM 24201 C CE . LYS M 1 179 ? 44.158 45.535 75.232 1.00 128.50 ? 179 LYS M CE 1 +ATOM 24202 N NZ . LYS M 1 179 ? 44.739 46.776 74.660 1.00 122.36 ? 179 LYS M NZ 1 +ATOM 24203 N N . THR M 1 180 ? 40.072 46.429 73.854 1.00 133.24 ? 180 THR M N 1 +ATOM 24204 C CA . THR M 1 180 ? 39.877 47.653 73.083 1.00 119.93 ? 180 THR M CA 1 +ATOM 24205 C C . THR M 1 180 ? 41.202 48.173 72.503 1.00 127.17 ? 180 THR M C 1 +ATOM 24206 O O . THR M 1 180 ? 42.237 48.236 73.205 1.00 148.09 ? 180 THR M O 1 +ATOM 24207 C CB . THR M 1 180 ? 39.192 48.748 73.918 1.00 122.98 ? 180 THR M CB 1 +ATOM 24208 O OG1 . THR M 1 180 ? 39.519 50.035 73.383 1.00 137.86 ? 180 THR M OG1 1 +ATOM 24209 C CG2 . THR M 1 180 ? 39.628 48.674 75.385 1.00 136.05 ? 180 THR M CG2 1 +ATOM 24210 N N . ILE M 1 181 ? 41.173 48.518 71.218 1.00 102.12 ? 181 ILE M N 1 +ATOM 24211 C CA . ILE M 1 181 ? 42.361 49.036 70.534 1.00 99.72 ? 181 ILE M CA 1 +ATOM 24212 C C . ILE M 1 181 ? 42.300 50.560 70.402 1.00 119.58 ? 181 ILE M C 1 +ATOM 24213 O O . ILE M 1 181 ? 41.374 51.107 69.789 1.00 114.46 ? 181 ILE M O 1 +ATOM 24214 C CB . ILE M 1 181 ? 42.518 48.420 69.136 1.00 100.83 ? 181 ILE M CB 1 +ATOM 24215 C CG1 . ILE M 1 181 ? 42.485 46.893 69.211 1.00 94.32 ? 181 ILE M CG1 1 +ATOM 24216 C CG2 . ILE M 1 181 ? 43.824 48.849 68.480 1.00 98.76 ? 181 ILE M CG2 1 +ATOM 24217 C CD1 . ILE M 1 181 ? 41.340 46.273 68.427 1.00 100.02 ? 181 ILE M CD1 1 +ATOM 24218 N N . LEU M 1 182 ? 43.265 51.243 71.030 1.00 134.68 ? 182 LEU M N 1 +ATOM 24219 C CA . LEU M 1 182 ? 43.290 52.719 71.096 1.00 136.15 ? 182 LEU M CA 1 +ATOM 24220 C C . LEU M 1 182 ? 44.118 53.372 69.990 1.00 120.30 ? 182 LEU M C 1 +ATOM 24221 O O . LEU M 1 182 ? 45.209 52.913 69.665 1.00 86.03 ? 182 LEU M O 1 +ATOM 24222 C CB . LEU M 1 182 ? 43.837 53.183 72.445 1.00 116.18 ? 182 LEU M CB 1 +ATOM 24223 C CG . LEU M 1 182 ? 43.940 54.702 72.630 1.00 104.02 ? 182 LEU M CG 1 +ATOM 24224 C CD1 . LEU M 1 182 ? 42.588 55.407 72.563 1.00 98.37 ? 182 LEU M CD1 1 +ATOM 24225 C CD2 . LEU M 1 182 ? 44.637 54.970 73.951 1.00 97.69 ? 182 LEU M CD2 1 +ATOM 24226 N N . SER M 1 183 ? 43.585 54.466 69.451 1.00 131.73 ? 183 SER M N 1 +ATOM 24227 C CA . SER M 1 183 ? 44.283 55.263 68.458 1.00 134.84 ? 183 SER M CA 1 +ATOM 24228 C C . SER M 1 183 ? 44.058 56.749 68.741 1.00 106.42 ? 183 SER M C 1 +ATOM 24229 O O . SER M 1 183 ? 42.943 57.151 69.090 1.00 71.11 ? 183 SER M O 1 +ATOM 24230 C CB . SER M 1 183 ? 43.785 54.904 67.046 1.00 161.66 ? 183 SER M CB 1 +ATOM 24231 O OG . SER M 1 183 ? 43.528 53.514 66.928 1.00 135.08 ? 183 SER M OG 1 +ATOM 24232 N N . TYR M 1 184 ? 45.097 57.555 68.546 1.00 88.34 ? 184 TYR M N 1 +ATOM 24233 C CA . TYR M 1 184 ? 44.968 58.995 68.709 1.00 90.50 ? 184 TYR M CA 1 +ATOM 24234 C C . TYR M 1 184 ? 45.949 59.815 67.868 1.00 106.63 ? 184 TYR M C 1 +ATOM 24235 O O . TYR M 1 184 ? 47.036 59.362 67.495 1.00 88.81 ? 184 TYR M O 1 +ATOM 24236 C CB . TYR M 1 184 ? 45.059 59.393 70.195 1.00 82.95 ? 184 TYR M CB 1 +ATOM 24237 C CG . TYR M 1 184 ? 46.333 58.991 70.892 1.00 73.93 ? 184 TYR M CG 1 +ATOM 24238 C CD1 . TYR M 1 184 ? 47.461 59.779 70.823 1.00 85.64 ? 184 TYR M CD1 1 +ATOM 24239 C CD2 . TYR M 1 184 ? 46.409 57.821 71.618 1.00 81.43 ? 184 TYR M CD2 1 +ATOM 24240 C CE1 . TYR M 1 184 ? 48.648 59.388 71.424 1.00 105.06 ? 184 TYR M CE1 1 +ATOM 24241 C CE2 . TYR M 1 184 ? 47.593 57.412 72.217 1.00 99.49 ? 184 TYR M CE2 1 +ATOM 24242 C CZ . TYR M 1 184 ? 48.713 58.196 72.117 1.00 104.23 ? 184 TYR M CZ 1 +ATOM 24243 O OH . TYR M 1 184 ? 49.891 57.794 72.720 1.00 109.64 ? 184 TYR M OH 1 +ATOM 24244 N N . GLU M 1 185 ? 45.546 61.056 67.606 1.00 123.70 ? 185 GLU M N 1 +ATOM 24245 C CA . GLU M 1 185 ? 46.312 62.004 66.795 1.00 142.32 ? 185 GLU M CA 1 +ATOM 24246 C C . GLU M 1 185 ? 46.358 63.350 67.494 1.00 139.50 ? 185 GLU M C 1 +ATOM 24247 O O . GLU M 1 185 ? 45.353 64.049 67.561 1.00 148.23 ? 185 GLU M O 1 +ATOM 24248 C CB . GLU M 1 185 ? 45.730 62.204 65.381 1.00 149.97 ? 185 GLU M CB 1 +ATOM 24249 C CG . GLU M 1 185 ? 45.240 60.953 64.678 1.00 179.88 ? 185 GLU M CG 1 +ATOM 24250 C CD . GLU M 1 185 ? 44.867 61.241 63.229 1.00 170.67 ? 185 GLU M CD 1 +ATOM 24251 O OE1 . GLU M 1 185 ? 44.967 62.407 62.802 1.00 113.14 ? 185 GLU M OE1 1 +ATOM 24252 O OE2 . GLU M 1 185 ? 44.526 60.283 62.511 1.00 185.12 ? 185 GLU M OE2 1 +ATOM 24253 N N . VAL M 1 186 ? 47.557 63.740 67.905 1.00 140.38 ? 186 VAL M N 1 +ATOM 24254 C CA . VAL M 1 186 ? 47.792 65.049 68.482 1.00 135.61 ? 186 VAL M CA 1 +ATOM 24255 C C . VAL M 1 186 ? 48.469 65.962 67.458 1.00 147.56 ? 186 VAL M C 1 +ATOM 24256 O O . VAL M 1 186 ? 49.355 65.533 66.717 1.00 108.13 ? 186 VAL M O 1 +ATOM 24257 C CB . VAL M 1 186 ? 48.675 64.932 69.729 1.00 155.53 ? 186 VAL M CB 1 +ATOM 24258 C CG1 . VAL M 1 186 ? 48.750 66.265 70.454 1.00 168.74 ? 186 VAL M CG1 1 +ATOM 24259 C CG2 . VAL M 1 186 ? 48.140 63.850 70.656 1.00 168.19 ? 186 VAL M CG2 1 +ATOM 24260 N N . GLN M 1 187 ? 48.039 67.222 67.415 1.00 172.01 ? 187 GLN M N 1 +ATOM 24261 C CA . GLN M 1 187 ? 48.551 68.172 66.423 1.00 160.33 ? 187 GLN M CA 1 +ATOM 24262 C C . GLN M 1 187 ? 48.564 69.593 66.955 1.00 135.62 ? 187 GLN M C 1 +ATOM 24263 O O . GLN M 1 187 ? 47.614 70.020 67.611 1.00 108.51 ? 187 GLN M O 1 +ATOM 24264 C CB . GLN M 1 187 ? 47.670 68.139 65.172 1.00 154.51 ? 187 GLN M CB 1 +ATOM 24265 C CG . GLN M 1 187 ? 48.024 67.078 64.154 1.00 170.53 ? 187 GLN M CG 1 +ATOM 24266 C CD . GLN M 1 187 ? 46.864 66.775 63.224 1.00 213.61 ? 187 GLN M CD 1 +ATOM 24267 O OE1 . GLN M 1 187 ? 46.131 67.684 62.820 1.00 178.77 ? 187 GLN M OE1 1 +ATOM 24268 N NE2 . GLN M 1 187 ? 46.668 65.491 62.904 1.00 246.44 ? 187 GLN M NE2 1 +ATOM 24269 N N . ALA M 1 188 ? 49.636 70.317 66.653 1.00 124.41 ? 188 ALA M N 1 +ATOM 24270 C CA . ALA M 1 188 ? 49.733 71.716 67.034 1.00 140.71 ? 188 ALA M CA 1 +ATOM 24271 C C . ALA M 1 188 ? 50.420 72.516 65.939 1.00 132.27 ? 188 ALA M C 1 +ATOM 24272 O O . ALA M 1 188 ? 51.367 72.045 65.323 1.00 93.87 ? 188 ALA M O 1 +ATOM 24273 C CB . ALA M 1 188 ? 50.481 71.858 68.352 1.00 156.51 ? 188 ALA M CB 1 +ATOM 24274 N N . GLY M 1 189 ? 49.921 73.720 65.689 1.00 140.33 ? 189 GLY M N 1 +ATOM 24275 C CA . GLY M 1 189 ? 50.477 74.573 64.652 1.00 151.25 ? 189 GLY M CA 1 +ATOM 24276 C C . GLY M 1 189 ? 50.430 76.050 64.996 1.00 150.13 ? 189 GLY M C 1 +ATOM 24277 O O . GLY M 1 189 ? 49.442 76.532 65.543 1.00 118.86 ? 189 GLY M O 1 +ATOM 24278 N N . VAL M 1 190 ? 51.508 76.761 64.675 1.00 167.36 ? 190 VAL M N 1 +ATOM 24279 C CA . VAL M 1 190 ? 51.580 78.200 64.884 1.00 174.97 ? 190 VAL M CA 1 +ATOM 24280 C C . VAL M 1 190 ? 51.683 78.911 63.532 1.00 190.22 ? 190 VAL M C 1 +ATOM 24281 O O . VAL M 1 190 ? 52.444 78.494 62.651 1.00 152.65 ? 190 VAL M O 1 +ATOM 24282 C CB . VAL M 1 190 ? 52.784 78.582 65.770 1.00 176.63 ? 190 VAL M CB 1 +ATOM 24283 C CG1 . VAL M 1 190 ? 52.692 80.042 66.186 1.00 156.21 ? 190 VAL M CG1 1 +ATOM 24284 C CG2 . VAL M 1 190 ? 52.870 77.668 66.991 1.00 163.61 ? 190 VAL M CG2 1 +ATOM 24285 N N . PHE M 1 191 ? 50.910 79.980 63.368 1.00 214.69 ? 191 PHE M N 1 +ATOM 24286 C CA . PHE M 1 191 ? 50.774 80.638 62.065 1.00 222.88 ? 191 PHE M CA 1 +ATOM 24287 C C . PHE M 1 191 ? 50.889 82.156 62.221 1.00 185.07 ? 191 PHE M C 1 +ATOM 24288 O O . PHE M 1 191 ? 50.230 82.738 63.086 1.00 146.04 ? 191 PHE M O 1 +ATOM 24289 C CB . PHE M 1 191 ? 49.423 80.261 61.429 1.00 227.49 ? 191 PHE M CB 1 +ATOM 24290 C CG . PHE M 1 191 ? 49.382 80.438 59.932 1.00 215.38 ? 191 PHE M CG 1 +ATOM 24291 C CD1 . PHE M 1 191 ? 49.357 81.705 59.373 1.00 197.57 ? 191 PHE M CD1 1 +ATOM 24292 C CD2 . PHE M 1 191 ? 49.365 79.337 59.084 1.00 201.31 ? 191 PHE M CD2 1 +ATOM 24293 C CE1 . PHE M 1 191 ? 49.308 81.871 57.999 1.00 173.94 ? 191 PHE M CE1 1 +ATOM 24294 C CE2 . PHE M 1 191 ? 49.325 79.499 57.709 1.00 173.80 ? 191 PHE M CE2 1 +ATOM 24295 C CZ . PHE M 1 191 ? 49.291 80.768 57.165 1.00 150.52 ? 191 PHE M CZ 1 +ATOM 24296 N N . LEU M 1 200 ? 55.451 83.224 58.800 1.00 139.12 ? 200 LEU M N 1 +ATOM 24297 C CA . LEU M 1 200 ? 55.799 82.211 59.789 1.00 149.33 ? 200 LEU M CA 1 +ATOM 24298 C C . LEU M 1 200 ? 54.690 81.176 59.923 1.00 193.92 ? 200 LEU M C 1 +ATOM 24299 O O . LEU M 1 200 ? 53.596 81.472 60.436 1.00 193.31 ? 200 LEU M O 1 +ATOM 24300 C CB . LEU M 1 200 ? 56.077 82.806 61.179 1.00 139.76 ? 200 LEU M CB 1 +ATOM 24301 C CG . LEU M 1 200 ? 56.269 81.751 62.284 1.00 131.24 ? 200 LEU M CG 1 +ATOM 24302 C CD1 . LEU M 1 200 ? 57.752 81.564 62.570 1.00 118.37 ? 200 LEU M CD1 1 +ATOM 24303 C CD2 . LEU M 1 200 ? 55.485 82.057 63.564 1.00 110.81 ? 200 LEU M CD2 1 +ATOM 24304 N N . GLU M 1 201 ? 54.989 79.957 59.482 1.00 199.80 ? 201 GLU M N 1 +ATOM 24305 C CA . GLU M 1 201 ? 54.213 78.786 59.873 1.00 167.10 ? 201 GLU M CA 1 +ATOM 24306 C C . GLU M 1 201 ? 55.116 77.784 60.573 1.00 137.91 ? 201 GLU M C 1 +ATOM 24307 O O . GLU M 1 201 ? 56.296 77.673 60.248 1.00 120.57 ? 201 GLU M O 1 +ATOM 24308 C CB . GLU M 1 201 ? 53.550 78.141 58.654 1.00 170.51 ? 201 GLU M CB 1 +ATOM 24309 C CG . GLU M 1 201 ? 52.386 77.237 59.027 1.00 180.27 ? 201 GLU M CG 1 +ATOM 24310 C CD . GLU M 1 201 ? 51.713 76.591 57.827 1.00 191.95 ? 201 GLU M CD 1 +ATOM 24311 O OE1 . GLU M 1 201 ? 51.365 77.314 56.869 1.00 217.55 ? 201 GLU M OE1 1 +ATOM 24312 O OE2 . GLU M 1 201 ? 51.527 75.356 57.843 1.00 203.82 ? 201 GLU M OE2 1 +ATOM 24313 N N . GLY M 1 202 ? 54.558 77.057 61.532 1.00 123.72 ? 202 GLY M N 1 +ATOM 24314 C CA . GLY M 1 202 ? 55.256 75.945 62.164 1.00 153.06 ? 202 GLY M CA 1 +ATOM 24315 C C . GLY M 1 202 ? 54.290 74.900 62.691 1.00 167.53 ? 202 GLY M C 1 +ATOM 24316 O O . GLY M 1 202 ? 53.367 75.228 63.440 1.00 204.56 ? 202 GLY M O 1 +ATOM 24317 N N . GLU M 1 203 ? 54.487 73.640 62.296 1.00 142.95 ? 203 GLU M N 1 +ATOM 24318 C CA . GLU M 1 203 ? 53.568 72.574 62.675 1.00 113.47 ? 203 GLU M CA 1 +ATOM 24319 C C . GLU M 1 203 ? 54.261 71.343 63.253 1.00 110.71 ? 203 GLU M C 1 +ATOM 24320 O O . GLU M 1 203 ? 55.269 70.870 62.726 1.00 87.42 ? 203 GLU M O 1 +ATOM 24321 C CB . GLU M 1 203 ? 52.716 72.162 61.478 1.00 122.35 ? 203 GLU M CB 1 +ATOM 24322 C CG . GLU M 1 203 ? 51.754 73.255 61.013 1.00 132.15 ? 203 GLU M CG 1 +ATOM 24323 C CD . GLU M 1 203 ? 50.811 72.831 59.889 1.00 145.39 ? 203 GLU M CD 1 +ATOM 24324 O OE1 . GLU M 1 203 ? 50.985 71.715 59.353 1.00 149.77 ? 203 GLU M OE1 1 +ATOM 24325 O OE2 . GLU M 1 203 ? 49.911 73.629 59.533 1.00 138.78 ? 203 GLU M OE2 1 +ATOM 24326 N N . VAL M 1 204 ? 53.694 70.836 64.347 1.00 118.91 ? 204 VAL M N 1 +ATOM 24327 C CA . VAL M 1 204 ? 54.100 69.565 64.941 1.00 110.10 ? 204 VAL M CA 1 +ATOM 24328 C C . VAL M 1 204 ? 52.898 68.641 65.023 1.00 115.11 ? 204 VAL M C 1 +ATOM 24329 O O . VAL M 1 204 ? 51.780 69.061 65.355 1.00 118.21 ? 204 VAL M O 1 +ATOM 24330 C CB . VAL M 1 204 ? 54.677 69.769 66.349 1.00 107.17 ? 204 VAL M CB 1 +ATOM 24331 C CG1 . VAL M 1 204 ? 54.754 68.457 67.115 1.00 110.80 ? 204 VAL M CG1 1 +ATOM 24332 C CG2 . VAL M 1 204 ? 56.053 70.411 66.243 1.00 116.45 ? 204 VAL M CG2 1 +ATOM 24333 N N . GLY M 1 205 ? 53.115 67.392 64.632 1.00 125.37 ? 205 GLY M N 1 +ATOM 24334 C CA . GLY M 1 205 ? 52.061 66.384 64.664 1.00 134.55 ? 205 GLY M CA 1 +ATOM 24335 C C . GLY M 1 205 ? 52.582 65.056 65.187 1.00 122.12 ? 205 GLY M C 1 +ATOM 24336 O O . GLY M 1 205 ? 53.759 64.724 64.999 1.00 97.78 ? 205 GLY M O 1 +ATOM 24337 N N . TYR M 1 206 ? 51.700 64.292 65.821 1.00 109.86 ? 206 TYR M N 1 +ATOM 24338 C CA . TYR M 1 206 ? 52.033 62.946 66.274 1.00 120.89 ? 206 TYR M CA 1 +ATOM 24339 C C . TYR M 1 206 ? 50.791 62.064 66.245 1.00 131.21 ? 206 TYR M C 1 +ATOM 24340 O O . TYR M 1 206 ? 49.703 62.522 66.579 1.00 130.00 ? 206 TYR M O 1 +ATOM 24341 C CB . TYR M 1 206 ? 52.598 62.988 67.699 1.00 135.76 ? 206 TYR M CB 1 +ATOM 24342 C CG . TYR M 1 206 ? 52.902 61.626 68.274 1.00 134.25 ? 206 TYR M CG 1 +ATOM 24343 C CD1 . TYR M 1 206 ? 54.016 60.912 67.868 1.00 125.23 ? 206 TYR M CD1 1 +ATOM 24344 C CD2 . TYR M 1 206 ? 52.050 61.040 69.207 1.00 144.34 ? 206 TYR M CD2 1 +ATOM 24345 C CE1 . TYR M 1 206 ? 54.272 59.646 68.366 1.00 129.53 ? 206 TYR M CE1 1 +ATOM 24346 C CE2 . TYR M 1 206 ? 52.299 59.777 69.709 1.00 126.46 ? 206 TYR M CE2 1 +ATOM 24347 C CZ . TYR M 1 206 ? 53.403 59.082 69.285 1.00 114.28 ? 206 TYR M CZ 1 +ATOM 24348 O OH . TYR M 1 206 ? 53.670 57.847 69.819 1.00 97.04 ? 206 TYR M OH 1 +ATOM 24349 N N . THR M 1 207 ? 50.954 60.797 65.869 1.00 135.58 ? 207 THR M N 1 +ATOM 24350 C CA . THR M 1 207 ? 49.831 59.852 65.839 1.00 135.26 ? 207 THR M CA 1 +ATOM 24351 C C . THR M 1 207 ? 50.243 58.478 66.359 1.00 113.53 ? 207 THR M C 1 +ATOM 24352 O O . THR M 1 207 ? 51.340 57.987 66.054 1.00 109.14 ? 207 THR M O 1 +ATOM 24353 C CB . THR M 1 207 ? 49.271 59.673 64.414 1.00 162.32 ? 207 THR M CB 1 +ATOM 24354 O OG1 . THR M 1 207 ? 50.287 59.133 63.562 1.00 206.22 ? 207 THR M OG1 1 +ATOM 24355 C CG2 . THR M 1 207 ? 48.806 60.996 63.838 1.00 178.72 ? 207 THR M CG2 1 +ATOM 24356 N N . SER M 1 208 ? 49.370 57.861 67.151 1.00 95.98 ? 208 SER M N 1 +ATOM 24357 C CA . SER M 1 208 ? 49.678 56.551 67.729 1.00 99.84 ? 208 SER M CA 1 +ATOM 24358 C C . SER M 1 208 ? 48.507 55.585 67.655 1.00 77.31 ? 208 SER M C 1 +ATOM 24359 O O . SER M 1 208 ? 47.412 55.895 68.118 1.00 49.80 ? 208 SER M O 1 +ATOM 24360 C CB . SER M 1 208 ? 50.146 56.679 69.193 1.00 108.67 ? 208 SER M CB 1 +ATOM 24361 O OG . SER M 1 208 ? 50.312 55.406 69.792 1.00 113.74 ? 208 SER M OG 1 +ATOM 24362 N N . ASN M 1 209 ? 48.782 54.405 67.101 1.00 86.42 ? 209 ASN M N 1 +ATOM 24363 C CA . ASN M 1 209 ? 47.830 53.292 67.068 1.00 97.55 ? 209 ASN M CA 1 +ATOM 24364 C C . ASN M 1 209 ? 48.352 52.163 67.925 1.00 91.35 ? 209 ASN M C 1 +ATOM 24365 O O . ASN M 1 209 ? 49.540 51.813 67.867 1.00 85.19 ? 209 ASN M O 1 +ATOM 24366 C CB . ASN M 1 209 ? 47.652 52.721 65.646 1.00 90.80 ? 209 ASN M CB 1 +ATOM 24367 C CG . ASN M 1 209 ? 46.884 53.618 64.724 1.00 94.96 ? 209 ASN M CG 1 +ATOM 24368 O OD1 . ASN M 1 209 ? 45.663 53.725 64.807 1.00 101.04 ? 209 ASN M OD1 1 +ATOM 24369 N ND2 . ASN M 1 209 ? 47.610 54.350 63.889 1.00 122.53 ? 209 ASN M ND2 1 +ATOM 24370 N N . GLU M 1 210 ? 47.455 51.552 68.683 1.00 97.00 ? 210 GLU M N 1 +ATOM 24371 C CA . GLU M 1 210 ? 47.779 50.288 69.342 1.00 105.70 ? 210 GLU M CA 1 +ATOM 24372 C C . GLU M 1 210 ? 47.881 49.216 68.274 1.00 92.81 ? 210 GLU M C 1 +ATOM 24373 O O . GLU M 1 210 ? 47.150 49.249 67.303 1.00 73.45 ? 210 GLU M O 1 +ATOM 24374 C CB . GLU M 1 210 ? 46.692 49.908 70.352 1.00 113.01 ? 210 GLU M CB 1 +ATOM 24375 C CG . GLU M 1 210 ? 47.203 49.369 71.688 1.00 104.12 ? 210 GLU M CG 1 +ATOM 24376 C CD . GLU M 1 210 ? 46.141 49.425 72.785 1.00 94.53 ? 210 GLU M CD 1 +ATOM 24377 O OE1 . GLU M 1 210 ? 45.180 50.253 72.712 1.00 58.31 ? 210 GLU M OE1 1 +ATOM 24378 O OE2 . GLU M 1 210 ? 46.228 48.571 73.687 1.00 85.81 ? 210 GLU M OE2 1 +ATOM 24379 N N . PRO M 1 211 ? 48.842 48.294 68.415 1.00 113.01 ? 211 PRO M N 1 +ATOM 24380 C CA . PRO M 1 211 ? 48.893 47.180 67.484 1.00 109.25 ? 211 PRO M CA 1 +ATOM 24381 C C . PRO M 1 211 ? 47.770 46.190 67.757 1.00 92.60 ? 211 PRO M C 1 +ATOM 24382 O O . PRO M 1 211 ? 47.598 45.729 68.891 1.00 70.33 ? 211 PRO M O 1 +ATOM 24383 C CB . PRO M 1 211 ? 50.260 46.548 67.754 1.00 128.81 ? 211 PRO M CB 1 +ATOM 24384 C CG . PRO M 1 211 ? 51.051 47.585 68.470 1.00 149.21 ? 211 PRO M CG 1 +ATOM 24385 C CD . PRO M 1 211 ? 50.034 48.338 69.278 1.00 149.88 ? 211 PRO M CD 1 +ATOM 24386 N N . VAL M 1 212 ? 46.970 45.930 66.726 1.00 96.97 ? 212 VAL M N 1 +ATOM 24387 C CA . VAL M 1 212 ? 45.857 44.991 66.818 1.00 107.21 ? 212 VAL M CA 1 +ATOM 24388 C C . VAL M 1 212 ? 46.437 43.606 67.147 1.00 111.56 ? 212 VAL M C 1 +ATOM 24389 O O . VAL M 1 212 ? 45.882 42.848 67.944 1.00 73.28 ? 212 VAL M O 1 +ATOM 24390 C CB . VAL M 1 212 ? 45.045 44.927 65.489 1.00 94.46 ? 212 VAL M CB 1 +ATOM 24391 C CG1 . VAL M 1 212 ? 43.827 44.017 65.660 1.00 82.57 ? 212 VAL M CG1 1 +ATOM 24392 C CG2 . VAL M 1 212 ? 44.633 46.324 65.012 1.00 67.13 ? 212 VAL M CG2 1 +ATOM 24393 N N . MET M 1 213 ? 47.542 43.300 66.471 1.00 127.83 ? 213 MET M N 1 +ATOM 24394 C CA . MET M 1 213 ? 48.460 42.192 66.775 1.00 116.29 ? 213 MET M CA 1 +ATOM 24395 C C . MET M 1 213 ? 48.653 41.933 68.270 1.00 118.28 ? 213 MET M C 1 +ATOM 24396 O O . MET M 1 213 ? 48.443 40.819 68.779 1.00 108.76 ? 213 MET M O 1 +ATOM 24397 C CB . MET M 1 213 ? 49.788 42.611 66.151 1.00 98.15 ? 213 MET M CB 1 +ATOM 24398 C CG . MET M 1 213 ? 50.922 41.626 66.205 1.00 78.84 ? 213 MET M CG 1 +ATOM 24399 S SD . MET M 1 213 ? 52.296 42.411 65.324 1.00 58.99 ? 213 MET M SD 1 +ATOM 24400 C CE . MET M 1 213 ? 53.289 42.677 66.797 1.00 99.39 ? 213 MET M CE 1 +ATOM 24401 N N . LEU M 1 214 ? 48.927 43.015 68.983 1.00 121.65 ? 214 LEU M N 1 +ATOM 24402 C CA . LEU M 1 214 ? 49.356 42.934 70.371 1.00 120.18 ? 214 LEU M CA 1 +ATOM 24403 C C . LEU M 1 214 ? 48.147 42.854 71.306 1.00 101.41 ? 214 LEU M C 1 +ATOM 24404 O O . LEU M 1 214 ? 48.206 42.228 72.378 1.00 101.89 ? 214 LEU M O 1 +ATOM 24405 C CB . LEU M 1 214 ? 50.206 44.156 70.717 1.00 126.01 ? 214 LEU M CB 1 +ATOM 24406 C CG . LEU M 1 214 ? 51.513 43.950 71.503 1.00 103.63 ? 214 LEU M CG 1 +ATOM 24407 C CD1 . LEU M 1 214 ? 52.512 43.021 70.799 1.00 67.28 ? 214 LEU M CD1 1 +ATOM 24408 C CD2 . LEU M 1 214 ? 52.120 45.334 71.782 1.00 105.94 ? 214 LEU M CD2 1 +ATOM 24409 N N . CYS M 1 215 ? 47.038 43.455 70.878 1.00 78.01 ? 215 CYS M N 1 +ATOM 24410 C CA . CYS M 1 215 ? 45.768 43.344 71.606 1.00 92.65 ? 215 CYS M CA 1 +ATOM 24411 C C . CYS M 1 215 ? 45.166 41.931 71.518 1.00 103.48 ? 215 CYS M C 1 +ATOM 24412 O O . CYS M 1 215 ? 44.637 41.382 72.520 1.00 104.42 ? 215 CYS M O 1 +ATOM 24413 C CB . CYS M 1 215 ? 44.748 44.322 71.051 1.00 81.76 ? 215 CYS M CB 1 +ATOM 24414 S SG . CYS M 1 215 ? 45.224 46.031 71.244 1.00 82.80 ? 215 CYS M SG 1 +ATOM 24415 N N . LEU M 1 216 ? 45.230 41.362 70.314 1.00 83.41 ? 216 LEU M N 1 +ATOM 24416 C CA . LEU M 1 216 ? 44.843 39.990 70.124 1.00 68.68 ? 216 LEU M CA 1 +ATOM 24417 C C . LEU M 1 216 ? 45.634 39.108 71.102 1.00 57.30 ? 216 LEU M C 1 +ATOM 24418 O O . LEU M 1 216 ? 45.062 38.254 71.806 1.00 57.19 ? 216 LEU M O 1 +ATOM 24419 C CB . LEU M 1 216 ? 45.067 39.561 68.683 1.00 66.91 ? 216 LEU M CB 1 +ATOM 24420 C CG . LEU M 1 216 ? 44.722 38.098 68.375 1.00 76.56 ? 216 LEU M CG 1 +ATOM 24421 C CD1 . LEU M 1 216 ? 43.278 37.760 68.708 1.00 88.43 ? 216 LEU M CD1 1 +ATOM 24422 C CD2 . LEU M 1 216 ? 44.988 37.784 66.912 1.00 77.00 ? 216 LEU M CD2 1 +ATOM 24423 N N . MET M 1 217 ? 46.939 39.322 71.157 1.00 55.86 ? 217 MET M N 1 +ATOM 24424 C CA . MET M 1 217 ? 47.793 38.458 71.948 1.00 88.61 ? 217 MET M CA 1 +ATOM 24425 C C . MET M 1 217 ? 47.393 38.574 73.412 1.00 77.54 ? 217 MET M C 1 +ATOM 24426 O O . MET M 1 217 ? 47.272 37.559 74.117 1.00 93.86 ? 217 MET M O 1 +ATOM 24427 C CB . MET M 1 217 ? 49.285 38.790 71.728 1.00 108.13 ? 217 MET M CB 1 +ATOM 24428 C CG . MET M 1 217 ? 50.187 37.551 71.598 1.00 118.25 ? 217 MET M CG 1 +ATOM 24429 S SD . MET M 1 217 ? 50.367 36.637 73.148 1.00 96.79 ? 217 MET M SD 1 +ATOM 24430 C CE . MET M 1 217 ? 51.187 35.141 72.635 1.00 116.26 ? 217 MET M CE 1 +ATOM 24431 N N . SER M 1 218 ? 47.215 39.808 73.861 1.00 71.49 ? 218 SER M N 1 +ATOM 24432 C CA . SER M 1 218 ? 46.867 40.095 75.259 1.00 75.48 ? 218 SER M CA 1 +ATOM 24433 C C . SER M 1 218 ? 45.586 39.366 75.641 1.00 72.12 ? 218 SER M C 1 +ATOM 24434 O O . SER M 1 218 ? 45.520 38.687 76.674 1.00 63.05 ? 218 SER M O 1 +ATOM 24435 C CB . SER M 1 218 ? 46.695 41.611 75.457 1.00 62.93 ? 218 SER M CB 1 +ATOM 24436 O OG . SER M 1 218 ? 46.538 41.917 76.822 1.00 56.39 ? 218 SER M OG 1 +ATOM 24437 N N . ALA M 1 219 ? 44.588 39.481 74.779 1.00 73.86 ? 219 ALA M N 1 +ATOM 24438 C CA . ALA M 1 219 ? 43.272 38.938 75.083 1.00 94.23 ? 219 ALA M CA 1 +ATOM 24439 C C . ALA M 1 219 ? 43.286 37.406 75.137 1.00 78.77 ? 219 ALA M C 1 +ATOM 24440 O O . ALA M 1 219 ? 42.588 36.785 75.948 1.00 86.59 ? 219 ALA M O 1 +ATOM 24441 C CB . ALA M 1 219 ? 42.269 39.437 74.056 1.00 110.34 ? 219 ALA M CB 1 +ATOM 24442 N N . ILE M 1 220 ? 44.131 36.802 74.317 1.00 68.82 ? 220 ILE M N 1 +ATOM 24443 C CA . ILE M 1 220 ? 44.263 35.345 74.314 1.00 69.75 ? 220 ILE M CA 1 +ATOM 24444 C C . ILE M 1 220 ? 44.903 34.854 75.614 1.00 75.70 ? 220 ILE M C 1 +ATOM 24445 O O . ILE M 1 220 ? 44.468 33.860 76.188 1.00 69.11 ? 220 ILE M O 1 +ATOM 24446 C CB . ILE M 1 220 ? 45.083 34.846 73.090 1.00 66.76 ? 220 ILE M CB 1 +ATOM 24447 C CG1 . ILE M 1 220 ? 44.259 35.074 71.801 1.00 77.38 ? 220 ILE M CG1 1 +ATOM 24448 C CG2 . ILE M 1 220 ? 45.453 33.374 73.238 1.00 48.85 ? 220 ILE M CG2 1 +ATOM 24449 C CD1 . ILE M 1 220 ? 45.057 35.009 70.521 1.00 66.97 ? 220 ILE M CD1 1 +ATOM 24450 N N . GLU M 1 221 ? 45.919 35.566 76.084 1.00 81.03 ? 221 GLU M N 1 +ATOM 24451 C CA . GLU M 1 221 ? 46.549 35.243 77.369 1.00 81.48 ? 221 GLU M CA 1 +ATOM 24452 C C . GLU M 1 221 ? 45.518 35.271 78.491 1.00 80.06 ? 221 GLU M C 1 +ATOM 24453 O O . GLU M 1 221 ? 45.395 34.325 79.269 1.00 80.53 ? 221 GLU M O 1 +ATOM 24454 C CB . GLU M 1 221 ? 47.677 36.242 77.664 1.00 100.03 ? 221 GLU M CB 1 +ATOM 24455 C CG . GLU M 1 221 ? 48.921 36.025 76.812 1.00 133.23 ? 221 GLU M CG 1 +ATOM 24456 C CD . GLU M 1 221 ? 49.873 37.222 76.793 1.00 152.01 ? 221 GLU M CD 1 +ATOM 24457 O OE1 . GLU M 1 221 ? 49.405 38.397 76.784 1.00 92.63 ? 221 GLU M OE1 1 +ATOM 24458 O OE2 . GLU M 1 221 ? 51.098 36.957 76.728 1.00 172.79 ? 221 GLU M OE2 1 +ATOM 24459 N N . THR M 1 222 ? 44.782 36.380 78.558 1.00 81.66 ? 222 THR M N 1 +ATOM 24460 C CA . THR M 1 222 ? 43.714 36.581 79.539 1.00 72.82 ? 222 THR M CA 1 +ATOM 24461 C C . THR M 1 222 ? 42.743 35.414 79.528 1.00 70.62 ? 222 THR M C 1 +ATOM 24462 O O . THR M 1 222 ? 42.386 34.873 80.574 1.00 75.65 ? 222 THR M O 1 +ATOM 24463 C CB . THR M 1 222 ? 42.928 37.873 79.212 1.00 71.61 ? 222 THR M CB 1 +ATOM 24464 O OG1 . THR M 1 222 ? 43.730 39.032 79.505 1.00 61.21 ? 222 THR M OG1 1 +ATOM 24465 C CG2 . THR M 1 222 ? 41.595 37.921 79.986 1.00 76.40 ? 222 THR M CG2 1 +ATOM 24466 N N . GLY M 1 223 ? 42.298 35.052 78.335 1.00 77.10 ? 223 GLY M N 1 +ATOM 24467 C CA . GLY M 1 223 ? 41.443 33.883 78.154 1.00 102.92 ? 223 GLY M CA 1 +ATOM 24468 C C . GLY M 1 223 ? 42.038 32.600 78.737 1.00 98.02 ? 223 GLY M C 1 +ATOM 24469 O O . GLY M 1 223 ? 41.312 31.785 79.323 1.00 95.47 ? 223 GLY M O 1 +ATOM 24470 N N . VAL M 1 224 ? 43.346 32.409 78.556 1.00 76.37 ? 224 VAL M N 1 +ATOM 24471 C CA . VAL M 1 224 ? 43.986 31.204 79.030 1.00 74.51 ? 224 VAL M CA 1 +ATOM 24472 C C . VAL M 1 224 ? 43.913 31.176 80.543 1.00 85.26 ? 224 VAL M C 1 +ATOM 24473 O O . VAL M 1 224 ? 43.658 30.137 81.148 1.00 102.06 ? 224 VAL M O 1 +ATOM 24474 C CB . VAL M 1 224 ? 45.449 31.131 78.578 1.00 80.58 ? 224 VAL M CB 1 +ATOM 24475 C CG1 . VAL M 1 224 ? 46.153 29.972 79.265 1.00 83.30 ? 224 VAL M CG1 1 +ATOM 24476 C CG2 . VAL M 1 224 ? 45.530 30.972 77.061 1.00 97.90 ? 224 VAL M CG2 1 +ATOM 24477 N N . ILE M 1 225 ? 44.137 32.331 81.165 1.00 101.64 ? 225 ILE M N 1 +ATOM 24478 C CA . ILE M 1 225 ? 44.067 32.426 82.627 1.00 95.11 ? 225 ILE M CA 1 +ATOM 24479 C C . ILE M 1 225 ? 42.674 32.057 83.121 1.00 92.48 ? 225 ILE M C 1 +ATOM 24480 O O . ILE M 1 225 ? 42.542 31.185 83.972 1.00 76.61 ? 225 ILE M O 1 +ATOM 24481 C CB . ILE M 1 225 ? 44.444 33.827 83.139 1.00 78.54 ? 225 ILE M CB 1 +ATOM 24482 C CG1 . ILE M 1 225 ? 45.930 34.084 82.906 1.00 77.10 ? 225 ILE M CG1 1 +ATOM 24483 C CG2 . ILE M 1 225 ? 44.158 33.933 84.622 1.00 85.19 ? 225 ILE M CG2 1 +ATOM 24484 C CD1 . ILE M 1 225 ? 46.314 35.544 82.978 1.00 86.99 ? 225 ILE M CD1 1 +ATOM 24485 N N . PHE M 1 226 ? 41.648 32.705 82.569 1.00 108.39 ? 226 PHE M N 1 +ATOM 24486 C CA . PHE M 1 226 ? 40.252 32.398 82.924 1.00 120.13 ? 226 PHE M CA 1 +ATOM 24487 C C . PHE M 1 226 ? 39.962 30.897 82.749 1.00 114.50 ? 226 PHE M C 1 +ATOM 24488 O O . PHE M 1 226 ? 39.140 30.344 83.491 1.00 151.26 ? 226 PHE M O 1 +ATOM 24489 C CB . PHE M 1 226 ? 39.237 33.235 82.104 1.00 107.28 ? 226 PHE M CB 1 +ATOM 24490 C CG . PHE M 1 226 ? 39.036 34.644 82.600 1.00 96.22 ? 226 PHE M CG 1 +ATOM 24491 C CD1 . PHE M 1 226 ? 38.587 34.893 83.873 1.00 93.45 ? 226 PHE M CD1 1 +ATOM 24492 C CD2 . PHE M 1 226 ? 39.279 35.733 81.754 1.00 105.13 ? 226 PHE M CD2 1 +ATOM 24493 C CE1 . PHE M 1 226 ? 38.440 36.200 84.324 1.00 98.62 ? 226 PHE M CE1 1 +ATOM 24494 C CE2 . PHE M 1 226 ? 39.113 37.039 82.192 1.00 85.70 ? 226 PHE M CE2 1 +ATOM 24495 C CZ . PHE M 1 226 ? 38.712 37.272 83.485 1.00 92.14 ? 226 PHE M CZ 1 +ATOM 24496 N N . LEU M 1 227 ? 40.597 30.252 81.763 1.00 78.02 ? 227 LEU M N 1 +ATOM 24497 C CA . LEU M 1 227 ? 40.375 28.818 81.525 1.00 74.19 ? 227 LEU M CA 1 +ATOM 24498 C C . LEU M 1 227 ? 40.943 28.039 82.654 1.00 72.57 ? 227 LEU M C 1 +ATOM 24499 O O . LEU M 1 227 ? 40.328 27.081 83.118 1.00 84.49 ? 227 LEU M O 1 +ATOM 24500 C CB . LEU M 1 227 ? 41.059 28.316 80.258 1.00 89.96 ? 227 LEU M CB 1 +ATOM 24501 C CG . LEU M 1 227 ? 40.193 27.746 79.134 1.00 105.39 ? 227 LEU M CG 1 +ATOM 24502 C CD1 . LEU M 1 227 ? 38.882 28.441 79.189 1.00 103.03 ? 227 LEU M CD1 1 +ATOM 24503 C CD2 . LEU M 1 227 ? 40.718 27.782 77.699 1.00 126.69 ? 227 LEU M CD2 1 +ATOM 24504 N N . ILE M 1 228 ? 42.152 28.403 83.058 1.00 72.97 ? 228 ILE M N 1 +ATOM 24505 C CA . ILE M 1 228 ? 42.854 27.653 84.094 1.00 93.65 ? 228 ILE M CA 1 +ATOM 24506 C C . ILE M 1 228 ? 42.105 27.796 85.408 1.00 87.75 ? 228 ILE M C 1 +ATOM 24507 O O . ILE M 1 228 ? 41.838 26.815 86.096 1.00 68.50 ? 228 ILE M O 1 +ATOM 24508 C CB . ILE M 1 228 ? 44.310 28.133 84.297 1.00 102.60 ? 228 ILE M CB 1 +ATOM 24509 C CG1 . ILE M 1 228 ? 45.156 27.864 83.048 1.00 116.31 ? 228 ILE M CG1 1 +ATOM 24510 C CG2 . ILE M 1 228 ? 44.940 27.398 85.461 1.00 99.75 ? 228 ILE M CG2 1 +ATOM 24511 C CD1 . ILE M 1 228 ? 46.471 28.612 83.010 1.00 108.93 ? 228 ILE M CD1 1 +ATOM 24512 N N . ASN M 1 229 ? 41.757 29.028 85.737 1.00 96.39 ? 229 ASN M N 1 +ATOM 24513 C CA . ASN M 1 229 ? 41.028 29.308 86.964 1.00 106.02 ? 229 ASN M CA 1 +ATOM 24514 C C . ASN M 1 229 ? 39.703 28.547 86.981 1.00 112.45 ? 229 ASN M C 1 +ATOM 24515 O O . ASN M 1 229 ? 39.319 27.965 87.998 1.00 135.89 ? 229 ASN M O 1 +ATOM 24516 C CB . ASN M 1 229 ? 40.794 30.822 87.096 1.00 109.53 ? 229 ASN M CB 1 +ATOM 24517 C CG . ASN M 1 229 ? 40.412 31.237 88.493 1.00 98.43 ? 229 ASN M CG 1 +ATOM 24518 O OD1 . ASN M 1 229 ? 40.718 30.545 89.472 1.00 101.91 ? 229 ASN M OD1 1 +ATOM 24519 N ND2 . ASN M 1 229 ? 39.758 32.390 88.602 1.00 82.37 ? 229 ASN M ND2 1 +ATOM 24520 N N . ASP M 1 230 ? 39.000 28.564 85.848 1.00 116.07 ? 230 ASP M N 1 +ATOM 24521 C CA . ASP M 1 230 ? 37.712 27.882 85.714 1.00 112.97 ? 230 ASP M CA 1 +ATOM 24522 C C . ASP M 1 230 ? 37.884 26.385 85.893 1.00 98.54 ? 230 ASP M C 1 +ATOM 24523 O O . ASP M 1 230 ? 37.088 25.741 86.598 1.00 104.03 ? 230 ASP M O 1 +ATOM 24524 C CB . ASP M 1 230 ? 37.100 28.156 84.342 1.00 122.97 ? 230 ASP M CB 1 +ATOM 24525 C CG . ASP M 1 230 ? 35.711 27.572 84.201 1.00 144.17 ? 230 ASP M CG 1 +ATOM 24526 O OD1 . ASP M 1 230 ? 34.779 28.128 84.809 1.00 182.30 ? 230 ASP M OD1 1 +ATOM 24527 O OD2 . ASP M 1 230 ? 35.540 26.560 83.504 1.00 161.96 ? 230 ASP M OD2 1 +ATOM 24528 N N . GLY M 1 231 ? 38.963 25.854 85.331 1.00 74.88 ? 231 GLY M N 1 +ATOM 24529 C CA . GLY M 1 231 ? 39.261 24.453 85.488 1.00 90.96 ? 231 GLY M CA 1 +ATOM 24530 C C . GLY M 1 231 ? 39.627 24.057 86.917 1.00 107.21 ? 231 GLY M C 1 +ATOM 24531 O O . GLY M 1 231 ? 39.280 22.950 87.389 1.00 126.37 ? 231 GLY M O 1 +ATOM 24532 N N . ILE M 1 232 ? 40.296 24.964 87.624 1.00 117.41 ? 232 ILE M N 1 +ATOM 24533 C CA . ILE M 1 232 ? 40.610 24.760 89.046 1.00 115.98 ? 232 ILE M CA 1 +ATOM 24534 C C . ILE M 1 232 ? 39.336 24.649 89.889 1.00 105.94 ? 232 ILE M C 1 +ATOM 24535 O O . ILE M 1 232 ? 39.166 23.684 90.627 1.00 105.22 ? 232 ILE M O 1 +ATOM 24536 C CB . ILE M 1 232 ? 41.479 25.910 89.596 1.00 119.69 ? 232 ILE M CB 1 +ATOM 24537 C CG1 . ILE M 1 232 ? 42.904 25.790 89.050 1.00 108.80 ? 232 ILE M CG1 1 +ATOM 24538 C CG2 . ILE M 1 232 ? 41.484 25.905 91.119 1.00 137.60 ? 232 ILE M CG2 1 +ATOM 24539 C CD1 . ILE M 1 232 ? 43.713 27.057 89.180 1.00 105.47 ? 232 ILE M CD1 1 +ATOM 24540 N N . ASP M 1 233 ? 38.430 25.614 89.727 1.00 110.63 ? 233 ASP M N 1 +ATOM 24541 C CA . ASP M 1 233 ? 37.114 25.582 90.377 1.00 100.27 ? 233 ASP M CA 1 +ATOM 24542 C C . ASP M 1 233 ? 36.373 24.268 90.086 1.00 100.63 ? 233 ASP M C 1 +ATOM 24543 O O . ASP M 1 233 ? 35.855 23.633 90.992 1.00 83.76 ? 233 ASP M O 1 +ATOM 24544 C CB . ASP M 1 233 ? 36.242 26.766 89.907 1.00 119.72 ? 233 ASP M CB 1 +ATOM 24545 C CG . ASP M 1 233 ? 36.796 28.119 90.332 1.00 125.51 ? 233 ASP M CG 1 +ATOM 24546 O OD1 . ASP M 1 233 ? 37.976 28.167 90.780 1.00 170.78 ? 233 ASP M OD1 1 +ATOM 24547 O OD2 . ASP M 1 233 ? 36.089 29.137 90.126 1.00 80.12 ? 233 ASP M OD2 1 +ATOM 24548 N N . ARG M 1 234 ? 36.302 23.877 88.812 1.00 98.11 ? 234 ARG M N 1 +ATOM 24549 C CA . ARG M 1 234 ? 35.466 22.747 88.398 1.00 95.13 ? 234 ARG M CA 1 +ATOM 24550 C C . ARG M 1 234 ? 36.107 21.382 88.628 1.00 90.03 ? 234 ARG M C 1 +ATOM 24551 O O . ARG M 1 234 ? 35.522 20.352 88.297 1.00 104.15 ? 234 ARG M O 1 +ATOM 24552 C CB . ARG M 1 234 ? 35.049 22.918 86.926 1.00 95.42 ? 234 ARG M CB 1 +ATOM 24553 C CG . ARG M 1 234 ? 33.995 23.994 86.750 1.00 80.33 ? 234 ARG M CG 1 +ATOM 24554 C CD . ARG M 1 234 ? 33.940 24.527 85.352 1.00 73.76 ? 234 ARG M CD 1 +ATOM 24555 N NE . ARG M 1 234 ? 32.964 25.604 85.303 1.00 94.45 ? 234 ARG M NE 1 +ATOM 24556 C CZ . ARG M 1 234 ? 31.905 25.633 84.499 1.00 116.99 ? 234 ARG M CZ 1 +ATOM 24557 N NH1 . ARG M 1 234 ? 31.688 24.635 83.653 1.00 150.13 ? 234 ARG M NH1 1 +ATOM 24558 N NH2 . ARG M 1 234 ? 31.073 26.675 84.514 1.00 99.14 ? 234 ARG M NH2 1 +ATOM 24559 N N . GLY M 1 235 ? 37.333 21.376 89.132 1.00 97.66 ? 235 GLY M N 1 +ATOM 24560 C CA . GLY M 1 235 ? 38.036 20.128 89.399 1.00 103.96 ? 235 GLY M CA 1 +ATOM 24561 C C . GLY M 1 235 ? 38.538 19.408 88.150 1.00 122.10 ? 235 GLY M C 1 +ATOM 24562 O O . GLY M 1 235 ? 38.620 18.182 88.141 1.00 121.52 ? 235 GLY M O 1 +ATOM 24563 N N . LEU M 1 236 ? 38.933 20.157 87.113 1.00 135.80 ? 236 LEU M N 1 +ATOM 24564 C CA . LEU M 1 236 ? 39.689 19.566 85.985 1.00 112.69 ? 236 LEU M CA 1 +ATOM 24565 C C . LEU M 1 236 ? 41.119 19.279 86.419 1.00 119.22 ? 236 LEU M C 1 +ATOM 24566 O O . LEU M 1 236 ? 41.636 18.175 86.222 1.00 151.57 ? 236 LEU M O 1 +ATOM 24567 C CB . LEU M 1 236 ? 39.726 20.487 84.765 1.00 120.17 ? 236 LEU M CB 1 +ATOM 24568 C CG . LEU M 1 236 ? 38.516 20.464 83.821 1.00 151.53 ? 236 LEU M CG 1 +ATOM 24569 C CD1 . LEU M 1 236 ? 37.366 21.274 84.407 1.00 179.33 ? 236 LEU M CD1 1 +ATOM 24570 C CD2 . LEU M 1 236 ? 38.903 21.022 82.459 1.00 160.70 ? 236 LEU M CD2 1 +ATOM 24571 N N . TRP M 1 237 ? 41.745 20.261 87.056 1.00 120.76 ? 237 TRP M N 1 +ATOM 24572 C CA . TRP M 1 237 ? 43.130 20.131 87.514 1.00 131.80 ? 237 TRP M CA 1 +ATOM 24573 C C . TRP M 1 237 ? 43.299 20.773 88.907 1.00 134.64 ? 237 TRP M C 1 +ATOM 24574 O O . TRP M 1 237 ? 42.441 21.531 89.358 1.00 107.94 ? 237 TRP M O 1 +ATOM 24575 C CB . TRP M 1 237 ? 44.086 20.756 86.487 1.00 117.32 ? 237 TRP M CB 1 +ATOM 24576 C CG . TRP M 1 237 ? 43.510 21.935 85.798 1.00 99.73 ? 237 TRP M CG 1 +ATOM 24577 C CD1 . TRP M 1 237 ? 43.221 23.142 86.357 1.00 103.73 ? 237 TRP M CD1 1 +ATOM 24578 C CD2 . TRP M 1 237 ? 43.114 22.021 84.431 1.00 88.51 ? 237 TRP M CD2 1 +ATOM 24579 N NE1 . TRP M 1 237 ? 42.665 23.972 85.424 1.00 127.22 ? 237 TRP M NE1 1 +ATOM 24580 C CE2 . TRP M 1 237 ? 42.613 23.315 84.224 1.00 110.18 ? 237 TRP M CE2 1 +ATOM 24581 C CE3 . TRP M 1 237 ? 43.128 21.133 83.362 1.00 91.68 ? 237 TRP M CE3 1 +ATOM 24582 C CZ2 . TRP M 1 237 ? 42.137 23.750 82.983 1.00 103.74 ? 237 TRP M CZ2 1 +ATOM 24583 C CZ3 . TRP M 1 237 ? 42.653 21.572 82.122 1.00 100.68 ? 237 TRP M CZ3 1 +ATOM 24584 C CH2 . TRP M 1 237 ? 42.162 22.865 81.950 1.00 94.55 ? 237 TRP M CH2 1 +ATOM 24585 N N . ASP M 1 238 ? 44.410 20.464 89.571 1.00 125.45 ? 238 ASP M N 1 +ATOM 24586 C CA . ASP M 1 238 ? 44.623 20.884 90.954 1.00 105.58 ? 238 ASP M CA 1 +ATOM 24587 C C . ASP M 1 238 ? 45.960 21.580 91.166 1.00 95.37 ? 238 ASP M C 1 +ATOM 24588 O O . ASP M 1 238 ? 46.973 21.241 90.517 1.00 100.96 ? 238 ASP M O 1 +ATOM 24589 C CB . ASP M 1 238 ? 44.516 19.685 91.885 1.00 120.78 ? 238 ASP M CB 1 +ATOM 24590 C CG . ASP M 1 238 ? 43.184 18.968 91.757 1.00 130.38 ? 238 ASP M CG 1 +ATOM 24591 O OD1 . ASP M 1 238 ? 43.047 18.160 90.812 1.00 142.83 ? 238 ASP M OD1 1 +ATOM 24592 O OD2 . ASP M 1 238 ? 42.292 19.177 92.614 1.00 129.78 ? 238 ASP M OD2 1 +ATOM 24593 N N . LEU M 1 239 ? 45.967 22.529 92.099 1.00 75.54 ? 239 LEU M N 1 +ATOM 24594 C CA . LEU M 1 239 ? 47.176 23.253 92.440 1.00 84.32 ? 239 LEU M CA 1 +ATOM 24595 C C . LEU M 1 239 ? 48.143 22.394 93.262 1.00 102.21 ? 239 LEU M C 1 +ATOM 24596 O O . LEU M 1 239 ? 47.731 21.572 94.085 1.00 102.39 ? 239 LEU M O 1 +ATOM 24597 C CB . LEU M 1 239 ? 46.833 24.510 93.232 1.00 91.07 ? 239 LEU M CB 1 +ATOM 24598 C CG . LEU M 1 239 ? 46.253 25.722 92.507 1.00 105.01 ? 239 LEU M CG 1 +ATOM 24599 C CD1 . LEU M 1 239 ? 46.082 26.900 93.458 1.00 100.19 ? 239 LEU M CD1 1 +ATOM 24600 C CD2 . LEU M 1 239 ? 47.138 26.124 91.349 1.00 121.61 ? 239 LEU M CD2 1 +ATOM 24601 N N . GLN M 1 240 ? 49.437 22.605 93.038 1.00 113.59 ? 240 GLN M N 1 +ATOM 24602 C CA . GLN M 1 240 ? 50.471 22.017 93.878 1.00 107.66 ? 240 GLN M CA 1 +ATOM 24603 C C . GLN M 1 240 ? 50.221 22.386 95.336 1.00 113.84 ? 240 GLN M C 1 +ATOM 24604 O O . GLN M 1 240 ? 50.105 21.519 96.198 1.00 110.00 ? 240 GLN M O 1 +ATOM 24605 C CB . GLN M 1 240 ? 51.860 22.509 93.432 1.00 112.13 ? 240 GLN M CB 1 +ATOM 24606 C CG . GLN M 1 240 ? 53.014 21.800 94.124 1.00 114.18 ? 240 GLN M CG 1 +ATOM 24607 C CD . GLN M 1 240 ? 53.065 20.323 93.760 1.00 126.82 ? 240 GLN M CD 1 +ATOM 24608 O OE1 . GLN M 1 240 ? 53.584 19.950 92.708 1.00 139.43 ? 240 GLN M OE1 1 +ATOM 24609 N NE2 . GLN M 1 240 ? 52.528 19.476 94.632 1.00 135.27 ? 240 GLN M NE2 1 +ATOM 24610 N N . ASN M 1 241 ? 50.158 23.688 95.595 1.00 149.45 ? 241 ASN M N 1 +ATOM 24611 C CA . ASN M 1 241 ? 49.917 24.220 96.936 1.00 160.78 ? 241 ASN M CA 1 +ATOM 24612 C C . ASN M 1 241 ? 48.494 24.719 97.069 1.00 159.48 ? 241 ASN M C 1 +ATOM 24613 O O . ASN M 1 241 ? 48.128 25.751 96.472 1.00 179.17 ? 241 ASN M O 1 +ATOM 24614 C CB . ASN M 1 241 ? 50.867 25.384 97.213 1.00 183.30 ? 241 ASN M CB 1 +ATOM 24615 C CG . ASN M 1 241 ? 52.037 24.983 98.071 1.00 183.50 ? 241 ASN M CG 1 +ATOM 24616 O OD1 . ASN M 1 241 ? 52.048 25.256 99.268 1.00 167.70 ? 241 ASN M OD1 1 +ATOM 24617 N ND2 . ASN M 1 241 ? 53.020 24.306 97.473 1.00 189.90 ? 241 ASN M ND2 1 +ATOM 24618 N N . LYS M 1 242 ? 47.699 24.005 97.860 1.00 128.77 ? 242 LYS M N 1 +ATOM 24619 C CA . LYS M 1 242 ? 46.301 24.377 98.052 1.00 120.59 ? 242 LYS M CA 1 +ATOM 24620 C C . LYS M 1 242 ? 46.234 25.723 98.762 1.00 133.40 ? 242 LYS M C 1 +ATOM 24621 O O . LYS M 1 242 ? 45.261 26.476 98.616 1.00 104.08 ? 242 LYS M O 1 +ATOM 24622 C CB . LYS M 1 242 ? 45.563 23.294 98.839 1.00 116.58 ? 242 LYS M CB 1 +ATOM 24623 C CG . LYS M 1 242 ? 45.773 21.890 98.289 1.00 120.43 ? 242 LYS M CG 1 +ATOM 24624 C CD . LYS M 1 242 ? 44.455 21.190 97.998 1.00 139.99 ? 242 LYS M CD 1 +ATOM 24625 C CE . LYS M 1 242 ? 44.472 20.532 96.625 1.00 151.43 ? 242 LYS M CE 1 +ATOM 24626 N NZ . LYS M 1 242 ? 43.261 19.706 96.370 1.00 155.64 ? 242 LYS M NZ 1 +ATOM 24627 N N . ALA M 1 243 ? 47.301 26.016 99.512 1.00 172.74 ? 243 ALA M N 1 +ATOM 24628 C CA . ALA M 1 243 ? 47.485 27.298 100.189 1.00 179.59 ? 243 ALA M CA 1 +ATOM 24629 C C . ALA M 1 243 ? 47.563 28.445 99.191 1.00 184.06 ? 243 ALA M C 1 +ATOM 24630 O O . ALA M 1 243 ? 47.386 29.611 99.574 1.00 243.93 ? 243 ALA M O 1 +ATOM 24631 C CB . ALA M 1 243 ? 48.749 27.266 101.049 1.00 163.87 ? 243 ALA M CB 1 +ATOM 24632 N N . GLU M 1 244 ? 47.855 28.129 97.927 1.00 148.55 ? 244 GLU M N 1 +ATOM 24633 C CA . GLU M 1 244 ? 48.022 29.168 96.918 1.00 142.25 ? 244 GLU M CA 1 +ATOM 24634 C C . GLU M 1 244 ? 46.731 29.445 96.164 1.00 126.07 ? 244 GLU M C 1 +ATOM 24635 O O . GLU M 1 244 ? 46.763 30.163 95.178 1.00 134.33 ? 244 GLU M O 1 +ATOM 24636 C CB . GLU M 1 244 ? 49.142 28.814 95.937 1.00 130.33 ? 244 GLU M CB 1 +ATOM 24637 C CG . GLU M 1 244 ? 50.546 28.937 96.517 1.00 136.29 ? 244 GLU M CG 1 +ATOM 24638 C CD . GLU M 1 244 ? 51.633 28.829 95.465 1.00 155.17 ? 244 GLU M CD 1 +ATOM 24639 O OE1 . GLU M 1 244 ? 51.910 27.701 94.993 1.00 179.55 ? 244 GLU M OE1 1 +ATOM 24640 O OE2 . GLU M 1 244 ? 52.199 29.877 95.085 1.00 170.67 ? 244 GLU M OE2 1 +ATOM 24641 N N . ARG M 1 245 ? 45.606 28.913 96.646 1.00 120.35 ? 245 ARG M N 1 +ATOM 24642 C CA . ARG M 1 245 ? 44.285 29.240 96.080 1.00 144.31 ? 245 ARG M CA 1 +ATOM 24643 C C . ARG M 1 245 ? 43.974 30.742 96.089 1.00 158.88 ? 245 ARG M C 1 +ATOM 24644 O O . ARG M 1 245 ? 43.378 31.253 95.142 1.00 166.25 ? 245 ARG M O 1 +ATOM 24645 C CB . ARG M 1 245 ? 43.167 28.504 96.820 1.00 149.33 ? 245 ARG M CB 1 +ATOM 24646 C CG . ARG M 1 245 ? 41.738 28.636 96.301 1.00 156.46 ? 245 ARG M CG 1 +ATOM 24647 C CD . ARG M 1 245 ? 41.614 28.093 94.938 1.00 159.96 ? 245 ARG M CD 1 +ATOM 24648 N NE . ARG M 1 245 ? 40.459 28.571 94.136 1.00 165.94 ? 245 ARG M NE 1 +ATOM 24649 C CZ . ARG M 1 245 ? 39.263 27.970 94.114 1.00 162.97 ? 245 ARG M CZ 1 +ATOM 24650 N NH1 . ARG M 1 245 ? 39.033 26.801 94.718 1.00 141.72 ? 245 ARG M NH1 1 +ATOM 24651 N NH2 . ARG M 1 245 ? 38.286 28.503 93.402 1.00 157.70 ? 245 ARG M NH2 1 +ATOM 24652 N N . GLN M 1 246 ? 44.416 31.443 97.133 1.00 169.38 ? 246 GLN M N 1 +ATOM 24653 C CA . GLN M 1 246 ? 44.130 32.876 97.260 1.00 163.69 ? 246 GLN M CA 1 +ATOM 24654 C C . GLN M 1 246 ? 45.259 33.739 96.686 1.00 148.97 ? 246 GLN M C 1 +ATOM 24655 O O . GLN M 1 246 ? 45.397 34.905 97.039 1.00 151.64 ? 246 GLN M O 1 +ATOM 24656 C CB . GLN M 1 246 ? 43.862 33.251 98.724 1.00 170.25 ? 246 GLN M CB 1 +ATOM 24657 C CG . GLN M 1 246 ? 42.551 32.720 99.280 1.00 178.91 ? 246 GLN M CG 1 +ATOM 24658 C CD . GLN M 1 246 ? 42.615 31.240 99.596 1.00 226.61 ? 246 GLN M CD 1 +ATOM 24659 O OE1 . GLN M 1 246 ? 43.588 30.763 100.191 1.00 272.18 ? 246 GLN M OE1 1 +ATOM 24660 N NE2 . GLN M 1 246 ? 41.571 30.504 99.221 1.00 239.14 ? 246 GLN M NE2 1 +ATOM 24661 N N . ASN M 1 247 ? 46.063 33.152 95.805 1.00 142.61 ? 247 ASN M N 1 +ATOM 24662 C CA . ASN M 1 247 ? 47.006 33.896 94.966 1.00 149.82 ? 247 ASN M CA 1 +ATOM 24663 C C . ASN M 1 247 ? 46.408 35.195 94.421 1.00 164.35 ? 247 ASN M C 1 +ATOM 24664 O O . ASN M 1 247 ? 45.248 35.218 93.999 1.00 180.95 ? 247 ASN M O 1 +ATOM 24665 C CB . ASN M 1 247 ? 47.429 33.028 93.785 1.00 138.70 ? 247 ASN M CB 1 +ATOM 24666 C CG . ASN M 1 247 ? 48.783 33.403 93.247 1.00 133.40 ? 247 ASN M CG 1 +ATOM 24667 O OD1 . ASN M 1 247 ? 48.905 33.947 92.142 1.00 159.00 ? 247 ASN M OD1 1 +ATOM 24668 N ND2 . ASN M 1 247 ? 49.819 33.081 94.009 1.00 140.99 ? 247 ASN M ND2 1 +ATOM 24669 N N . ASP M 1 248 ? 47.199 36.268 94.430 1.00 168.64 ? 248 ASP M N 1 +ATOM 24670 C CA . ASP M 1 248 ? 46.724 37.604 94.009 1.00 172.48 ? 248 ASP M CA 1 +ATOM 24671 C C . ASP M 1 248 ? 46.087 37.563 92.620 1.00 160.71 ? 248 ASP M C 1 +ATOM 24672 O O . ASP M 1 248 ? 45.012 38.130 92.379 1.00 154.11 ? 248 ASP M O 1 +ATOM 24673 C CB . ASP M 1 248 ? 47.887 38.606 93.983 1.00 159.05 ? 248 ASP M CB 1 +ATOM 24674 C CG . ASP M 1 248 ? 48.380 38.980 95.373 1.00 148.42 ? 248 ASP M CG 1 +ATOM 24675 O OD1 . ASP M 1 248 ? 47.548 39.151 96.285 1.00 135.95 ? 248 ASP M OD1 1 +ATOM 24676 O OD2 . ASP M 1 248 ? 49.605 39.149 95.540 1.00 140.50 ? 248 ASP M OD2 1 +ATOM 24677 N N . ILE M 1 249 ? 46.775 36.886 91.710 1.00 146.43 ? 249 ILE M N 1 +ATOM 24678 C CA . ILE M 1 249 ? 46.356 36.817 90.326 1.00 143.74 ? 249 ILE M CA 1 +ATOM 24679 C C . ILE M 1 249 ? 45.061 36.014 90.224 1.00 119.16 ? 249 ILE M C 1 +ATOM 24680 O O . ILE M 1 249 ? 44.075 36.461 89.607 1.00 151.03 ? 249 ILE M O 1 +ATOM 24681 C CB . ILE M 1 249 ? 47.459 36.173 89.452 1.00 150.07 ? 249 ILE M CB 1 +ATOM 24682 C CG1 . ILE M 1 249 ? 48.726 37.044 89.459 1.00 133.25 ? 249 ILE M CG1 1 +ATOM 24683 C CG2 . ILE M 1 249 ? 46.975 36.007 88.019 1.00 189.22 ? 249 ILE M CG2 1 +ATOM 24684 C CD1 . ILE M 1 249 ? 49.985 36.310 89.061 1.00 113.76 ? 249 ILE M CD1 1 +ATOM 24685 N N . LEU M 1 250 ? 45.061 34.836 90.835 1.00 93.96 ? 250 LEU M N 1 +ATOM 24686 C CA . LEU M 1 250 ? 43.900 33.954 90.777 1.00 108.31 ? 250 LEU M CA 1 +ATOM 24687 C C . LEU M 1 250 ? 42.629 34.605 91.334 1.00 134.80 ? 250 LEU M C 1 +ATOM 24688 O O . LEU M 1 250 ? 41.525 34.372 90.824 1.00 120.29 ? 250 LEU M O 1 +ATOM 24689 C CB . LEU M 1 250 ? 44.186 32.652 91.517 1.00 94.15 ? 250 LEU M CB 1 +ATOM 24690 C CG . LEU M 1 250 ? 45.001 31.626 90.731 1.00 92.10 ? 250 LEU M CG 1 +ATOM 24691 C CD1 . LEU M 1 250 ? 45.494 30.488 91.613 1.00 91.57 ? 250 LEU M CD1 1 +ATOM 24692 C CD2 . LEU M 1 250 ? 44.181 31.069 89.583 1.00 97.26 ? 250 LEU M CD2 1 +ATOM 24693 N N . VAL M 1 251 ? 42.774 35.369 92.417 1.00 157.19 ? 251 VAL M N 1 +ATOM 24694 C CA . VAL M 1 251 ? 41.625 36.053 93.029 1.00 160.09 ? 251 VAL M CA 1 +ATOM 24695 C C . VAL M 1 251 ? 41.209 37.279 92.220 1.00 152.17 ? 251 VAL M C 1 +ATOM 24696 O O . VAL M 1 251 ? 40.050 37.701 92.270 1.00 135.04 ? 251 VAL M O 1 +ATOM 24697 C CB . VAL M 1 251 ? 41.887 36.471 94.500 1.00 146.02 ? 251 VAL M CB 1 +ATOM 24698 C CG1 . VAL M 1 251 ? 42.298 35.258 95.325 1.00 140.22 ? 251 VAL M CG1 1 +ATOM 24699 C CG2 . VAL M 1 251 ? 42.919 37.584 94.589 1.00 137.32 ? 251 VAL M CG2 1 +ATOM 24700 N N . LYS M 1 252 ? 42.150 37.835 91.467 1.00 145.64 ? 252 LYS M N 1 +ATOM 24701 C CA . LYS M 1 252 ? 41.855 38.954 90.583 1.00 147.48 ? 252 LYS M CA 1 +ATOM 24702 C C . LYS M 1 252 ? 40.934 38.502 89.437 1.00 156.08 ? 252 LYS M C 1 +ATOM 24703 O O . LYS M 1 252 ? 39.918 39.145 89.142 1.00 150.39 ? 252 LYS M O 1 +ATOM 24704 C CB . LYS M 1 252 ? 43.171 39.540 90.061 1.00 141.41 ? 252 LYS M CB 1 +ATOM 24705 C CG . LYS M 1 252 ? 43.028 40.702 89.094 1.00 138.30 ? 252 LYS M CG 1 +ATOM 24706 C CD . LYS M 1 252 ? 44.404 41.165 88.628 1.00 144.07 ? 252 LYS M CD 1 +ATOM 24707 C CE . LYS M 1 252 ? 44.453 41.342 87.117 1.00 166.86 ? 252 LYS M CE 1 +ATOM 24708 N NZ . LYS M 1 252 ? 45.839 41.534 86.606 1.00 161.02 ? 252 LYS M NZ 1 +ATOM 24709 N N . TYR M 1 253 ? 41.271 37.365 88.830 1.00 178.70 ? 253 TYR M N 1 +ATOM 24710 C CA . TYR M 1 253 ? 40.493 36.822 87.711 1.00 185.98 ? 253 TYR M CA 1 +ATOM 24711 C C . TYR M 1 253 ? 39.222 36.146 88.206 1.00 180.73 ? 253 TYR M C 1 +ATOM 24712 O O . TYR M 1 253 ? 38.195 36.162 87.513 1.00 223.66 ? 253 TYR M O 1 +ATOM 24713 C CB . TYR M 1 253 ? 41.337 35.846 86.867 1.00 169.41 ? 253 TYR M CB 1 +ATOM 24714 C CG . TYR M 1 253 ? 42.390 36.561 86.040 1.00 146.41 ? 253 TYR M CG 1 +ATOM 24715 C CD1 . TYR M 1 253 ? 42.077 37.125 84.807 1.00 147.34 ? 253 TYR M CD1 1 +ATOM 24716 C CD2 . TYR M 1 253 ? 43.678 36.759 86.540 1.00 128.84 ? 253 TYR M CD2 1 +ATOM 24717 C CE1 . TYR M 1 253 ? 43.026 37.836 84.093 1.00 157.30 ? 253 TYR M CE1 1 +ATOM 24718 C CE2 . TYR M 1 253 ? 44.636 37.477 85.828 1.00 104.16 ? 253 TYR M CE2 1 +ATOM 24719 C CZ . TYR M 1 253 ? 44.303 38.007 84.611 1.00 129.49 ? 253 TYR M CZ 1 +ATOM 24720 O OH . TYR M 1 253 ? 45.241 38.692 83.881 1.00 130.11 ? 253 TYR M OH 1 +ATOM 24721 N N . ARG M 1 254 ? 39.274 35.611 89.421 1.00 132.41 ? 254 ARG M N 1 +ATOM 24722 C CA . ARG M 1 254 ? 38.085 35.081 90.072 1.00 146.81 ? 254 ARG M CA 1 +ATOM 24723 C C . ARG M 1 254 ? 37.102 36.216 90.357 1.00 161.34 ? 254 ARG M C 1 +ATOM 24724 O O . ARG M 1 254 ? 35.888 36.013 90.351 1.00 170.10 ? 254 ARG M O 1 +ATOM 24725 C CB . ARG M 1 254 ? 38.456 34.365 91.371 1.00 148.05 ? 254 ARG M CB 1 +ATOM 24726 C CG . ARG M 1 254 ? 37.277 33.725 92.086 1.00 145.68 ? 254 ARG M CG 1 +ATOM 24727 C CD . ARG M 1 254 ? 37.706 32.490 92.862 1.00 134.54 ? 254 ARG M CD 1 +ATOM 24728 N NE . ARG M 1 254 ? 38.483 32.832 94.049 1.00 140.85 ? 254 ARG M NE 1 +ATOM 24729 C CZ . ARG M 1 254 ? 39.749 32.477 94.241 1.00 144.84 ? 254 ARG M CZ 1 +ATOM 24730 N NH1 . ARG M 1 254 ? 40.387 31.766 93.322 1.00 99.11 ? 254 ARG M NH1 1 +ATOM 24731 N NH2 . ARG M 1 254 ? 40.378 32.832 95.353 1.00 192.17 ? 254 ARG M NH2 1 +ATOM 24732 N N . HIS M 1 255 ? 37.636 37.410 90.603 1.00 172.85 ? 255 HIS M N 1 +ATOM 24733 C CA . HIS M 1 255 ? 36.802 38.593 90.848 1.00 183.58 ? 255 HIS M CA 1 +ATOM 24734 C C . HIS M 1 255 ? 36.169 39.133 89.574 1.00 170.46 ? 255 HIS M C 1 +ATOM 24735 O O . HIS M 1 255 ? 35.035 39.618 89.599 1.00 209.80 ? 255 HIS M O 1 +ATOM 24736 C CB . HIS M 1 255 ? 37.602 39.704 91.542 1.00 185.87 ? 255 HIS M CB 1 +ATOM 24737 C CG . HIS M 1 255 ? 37.247 39.887 92.987 1.00 224.00 ? 255 HIS M CG 1 +ATOM 24738 N ND1 . HIS M 1 255 ? 37.649 39.004 93.968 1.00 241.51 ? 255 HIS M ND1 1 +ATOM 24739 C CD2 . HIS M 1 255 ? 36.495 40.826 93.611 1.00 217.98 ? 255 HIS M CD2 1 +ATOM 24740 C CE1 . HIS M 1 255 ? 37.176 39.404 95.137 1.00 230.59 ? 255 HIS M CE1 1 +ATOM 24741 N NE2 . HIS M 1 255 ? 36.469 40.504 94.947 1.00 210.47 ? 255 HIS M NE2 1 +ATOM 24742 N N . MET M 1 256 ? 36.875 39.013 88.457 1.00 150.81 ? 256 MET M N 1 +ATOM 24743 C CA . MET M 1 256 ? 36.317 39.461 87.184 1.00 161.29 ? 256 MET M CA 1 +ATOM 24744 C C . MET M 1 256 ? 35.125 38.588 86.730 1.00 133.30 ? 256 MET M C 1 +ATOM 24745 O O . MET M 1 256 ? 34.243 39.069 86.001 1.00 112.11 ? 256 MET M O 1 +ATOM 24746 C CB . MET M 1 256 ? 37.409 39.522 86.104 1.00 191.31 ? 256 MET M CB 1 +ATOM 24747 C CG . MET M 1 256 ? 38.633 40.337 86.513 1.00 185.71 ? 256 MET M CG 1 +ATOM 24748 S SD . MET M 1 256 ? 39.689 40.889 85.163 1.00 180.63 ? 256 MET M SD 1 +ATOM 24749 C CE . MET M 1 256 ? 38.611 42.094 84.371 1.00 149.02 ? 256 MET M CE 1 +ATOM 24750 N N . SER M 1 257 ? 35.070 37.346 87.216 1.00 124.61 ? 257 SER M N 1 +ATOM 24751 C CA . SER M 1 257 ? 33.921 36.453 87.009 1.00 128.13 ? 257 SER M CA 1 +ATOM 24752 C C . SER M 1 257 ? 32.730 36.785 87.914 1.00 129.99 ? 257 SER M C 1 +ATOM 24753 O O . SER M 1 257 ? 31.905 37.629 87.545 1.00 156.17 ? 257 SER M O 1 +ATOM 24754 C CB . SER M 1 257 ? 34.329 35.004 87.257 1.00 132.45 ? 257 SER M CB 1 +ATOM 24755 O OG . SER M 1 257 ? 35.615 34.734 86.709 1.00 129.63 ? 257 SER M OG 1 +ATOM 24756 N N . LEU N 1 2 ? 61.604 55.583 71.629 1.00 104.15 ? 2 LEU N N 1 +ATOM 24757 C CA . LEU N 1 2 ? 60.161 55.686 71.222 1.00 120.35 ? 2 LEU N CA 1 +ATOM 24758 C C . LEU N 1 2 ? 60.011 55.579 69.685 1.00 129.43 ? 2 LEU N C 1 +ATOM 24759 O O . LEU N 1 2 ? 59.702 56.563 68.978 1.00 100.17 ? 2 LEU N O 1 +ATOM 24760 C CB . LEU N 1 2 ? 59.525 56.975 71.767 1.00 138.46 ? 2 LEU N CB 1 +ATOM 24761 C CG . LEU N 1 2 ? 59.452 57.194 73.299 1.00 123.42 ? 2 LEU N CG 1 +ATOM 24762 C CD1 . LEU N 1 2 ? 58.811 58.549 73.588 1.00 114.75 ? 2 LEU N CD1 1 +ATOM 24763 C CD2 . LEU N 1 2 ? 58.717 56.085 74.062 1.00 112.31 ? 2 LEU N CD2 1 +ATOM 24764 N N . THR N 1 3 ? 60.406 54.404 69.192 1.00 159.39 ? 3 THR N N 1 +ATOM 24765 C CA . THR N 1 3 ? 60.093 53.913 67.847 1.00 143.60 ? 3 THR N CA 1 +ATOM 24766 C C . THR N 1 3 ? 59.776 52.403 67.885 1.00 152.24 ? 3 THR N C 1 +ATOM 24767 O O . THR N 1 3 ? 59.470 51.786 66.853 1.00 181.78 ? 3 THR N O 1 +ATOM 24768 C CB . THR N 1 3 ? 61.259 54.142 66.848 1.00 115.98 ? 3 THR N CB 1 +ATOM 24769 O OG1 . THR N 1 3 ? 62.374 53.292 67.183 1.00 67.39 ? 3 THR N OG1 1 +ATOM 24770 C CG2 . THR N 1 3 ? 61.668 55.624 66.813 1.00 100.55 ? 3 THR N CG2 1 +ATOM 24771 N N . ALA N 1 4 ? 59.933 51.797 69.060 1.00 145.08 ? 4 ALA N N 1 +ATOM 24772 C CA . ALA N 1 4 ? 59.305 50.510 69.350 1.00 128.92 ? 4 ALA N CA 1 +ATOM 24773 C C . ALA N 1 4 ? 57.799 50.764 69.563 1.00 127.76 ? 4 ALA N C 1 +ATOM 24774 O O . ALA N 1 4 ? 57.325 51.890 69.368 1.00 129.58 ? 4 ALA N O 1 +ATOM 24775 C CB . ALA N 1 4 ? 59.959 49.845 70.563 1.00 109.47 ? 4 ALA N CB 1 +ATOM 24776 N N . PRO N 1 5 ? 57.014 49.715 69.865 1.00 136.48 ? 5 PRO N N 1 +ATOM 24777 C CA . PRO N 1 5 ? 55.595 49.994 69.717 1.00 127.73 ? 5 PRO N CA 1 +ATOM 24778 C C . PRO N 1 5 ? 55.009 50.803 70.895 1.00 121.43 ? 5 PRO N C 1 +ATOM 24779 O O . PRO N 1 5 ? 55.667 50.988 71.912 1.00 147.37 ? 5 PRO N O 1 +ATOM 24780 C CB . PRO N 1 5 ? 54.979 48.594 69.629 1.00 128.08 ? 5 PRO N CB 1 +ATOM 24781 C CG . PRO N 1 5 ? 55.908 47.709 70.394 1.00 159.62 ? 5 PRO N CG 1 +ATOM 24782 C CD . PRO N 1 5 ? 57.258 48.387 70.465 1.00 164.94 ? 5 PRO N CD 1 +ATOM 24783 N N . PRO N 1 6 ? 53.782 51.314 70.739 1.00 125.21 ? 6 PRO N N 1 +ATOM 24784 C CA . PRO N 1 6 ? 53.005 51.844 71.859 1.00 119.20 ? 6 PRO N CA 1 +ATOM 24785 C C . PRO N 1 6 ? 52.398 50.746 72.709 1.00 112.02 ? 6 PRO N C 1 +ATOM 24786 O O . PRO N 1 6 ? 52.087 49.661 72.206 1.00 98.46 ? 6 PRO N O 1 +ATOM 24787 C CB . PRO N 1 6 ? 51.917 52.688 71.187 1.00 139.69 ? 6 PRO N CB 1 +ATOM 24788 C CG . PRO N 1 6 ? 51.869 52.258 69.763 1.00 130.52 ? 6 PRO N CG 1 +ATOM 24789 C CD . PRO N 1 6 ? 53.133 51.525 69.432 1.00 140.87 ? 6 PRO N CD 1 +ATOM 24790 N N . LYS N 1 7 ? 52.206 51.026 73.997 1.00 111.50 ? 7 LYS N N 1 +ATOM 24791 C CA . LYS N 1 7 ? 51.820 49.983 74.933 1.00 110.50 ? 7 LYS N CA 1 +ATOM 24792 C C . LYS N 1 7 ? 50.319 49.923 75.022 1.00 104.74 ? 7 LYS N C 1 +ATOM 24793 O O . LYS N 1 7 ? 49.557 50.652 74.341 1.00 89.31 ? 7 LYS N O 1 +ATOM 24794 C CB . LYS N 1 7 ? 52.378 50.230 76.367 1.00 123.83 ? 7 LYS N CB 1 +ATOM 24795 C CG . LYS N 1 7 ? 53.478 51.308 76.374 1.00 124.69 ? 7 LYS N CG 1 +ATOM 24796 C CD . LYS N 1 7 ? 54.808 50.693 75.974 1.00 119.93 ? 7 LYS N CD 1 +ATOM 24797 C CE . LYS N 1 7 ? 55.826 51.768 75.637 1.00 106.64 ? 7 LYS N CE 1 +ATOM 24798 N NZ . LYS N 1 7 ? 57.218 51.330 75.919 1.00 102.82 ? 7 LYS N NZ 1 +ATOM 24799 N N . GLU N 1 8 ? 49.935 49.063 75.942 1.00 100.75 ? 8 GLU N N 1 +ATOM 24800 C CA . GLU N 1 8 ? 48.553 48.706 76.134 1.00 97.04 ? 8 GLU N CA 1 +ATOM 24801 C C . GLU N 1 8 ? 47.714 49.886 76.559 1.00 82.36 ? 8 GLU N C 1 +ATOM 24802 O O . GLU N 1 8 ? 47.908 50.437 77.642 1.00 77.81 ? 8 GLU N O 1 +ATOM 24803 C CB . GLU N 1 8 ? 48.421 47.634 77.201 1.00 120.09 ? 8 GLU N CB 1 +ATOM 24804 C CG . GLU N 1 8 ? 47.723 46.355 76.855 1.00 145.13 ? 8 GLU N CG 1 +ATOM 24805 C CD . GLU N 1 8 ? 47.622 45.424 78.067 1.00 155.26 ? 8 GLU N CD 1 +ATOM 24806 O OE1 . GLU N 1 8 ? 48.643 45.114 78.716 1.00 133.88 ? 8 GLU N OE1 1 +ATOM 24807 O OE2 . GLU N 1 8 ? 46.560 44.870 78.312 1.00 168.02 ? 8 GLU N OE2 1 +ATOM 24808 N N . ALA N 1 9 ? 46.743 50.216 75.727 1.00 86.51 ? 9 ALA N N 1 +ATOM 24809 C CA . ALA N 1 9 ? 45.673 51.105 76.097 1.00 100.15 ? 9 ALA N CA 1 +ATOM 24810 C C . ALA N 1 9 ? 44.423 50.291 76.513 1.00 112.57 ? 9 ALA N C 1 +ATOM 24811 O O . ALA N 1 9 ? 43.760 49.667 75.664 1.00 101.31 ? 9 ALA N O 1 +ATOM 24812 C CB . ALA N 1 9 ? 45.353 52.014 74.927 1.00 104.99 ? 9 ALA N CB 1 +ATOM 24813 N N . ALA N 1 10 ? 44.092 50.350 77.808 1.00 89.03 ? 10 ALA N N 1 +ATOM 24814 C CA . ALA N 1 10 ? 43.006 49.561 78.423 1.00 86.22 ? 10 ALA N CA 1 +ATOM 24815 C C . ALA N 1 10 ? 43.484 48.161 78.780 1.00 88.46 ? 10 ALA N C 1 +ATOM 24816 O O . ALA N 1 10 ? 44.492 47.706 78.277 1.00 71.68 ? 10 ALA N O 1 +ATOM 24817 C CB . ALA N 1 10 ? 41.756 49.498 77.528 1.00 80.64 ? 10 ALA N CB 1 +ATOM 24818 N N . ARG N 1 11 ? 42.731 47.479 79.633 1.00 111.67 ? 11 ARG N N 1 +ATOM 24819 C CA . ARG N 1 11 ? 43.048 46.104 80.029 1.00 136.56 ? 11 ARG N CA 1 +ATOM 24820 C C . ARG N 1 11 ? 42.160 45.131 79.256 1.00 116.34 ? 11 ARG N C 1 +ATOM 24821 O O . ARG N 1 11 ? 41.033 45.468 78.950 1.00 99.17 ? 11 ARG N O 1 +ATOM 24822 C CB . ARG N 1 11 ? 42.838 45.904 81.550 1.00 176.72 ? 11 ARG N CB 1 +ATOM 24823 C CG . ARG N 1 11 ? 41.395 46.027 82.018 1.00 183.97 ? 11 ARG N CG 1 +ATOM 24824 C CD . ARG N 1 11 ? 41.322 46.489 83.473 1.00 192.34 ? 11 ARG N CD 1 +ATOM 24825 N NE . ARG N 1 11 ? 40.878 47.877 83.591 1.00 207.04 ? 11 ARG N NE 1 +ATOM 24826 C CZ . ARG N 1 11 ? 40.703 48.504 84.752 1.00 208.14 ? 11 ARG N CZ 1 +ATOM 24827 N NH1 . ARG N 1 11 ? 40.862 47.848 85.896 1.00 226.41 ? 11 ARG N NH1 1 +ATOM 24828 N NH2 . ARG N 1 11 ? 40.337 49.778 84.773 1.00 191.73 ? 11 ARG N NH2 1 +ATOM 24829 N N . PRO N 1 12 ? 42.640 43.894 79.008 1.00 96.48 ? 12 PRO N N 1 +ATOM 24830 C CA . PRO N 1 12 ? 41.702 42.855 78.633 1.00 76.52 ? 12 PRO N CA 1 +ATOM 24831 C C . PRO N 1 12 ? 40.694 42.571 79.750 1.00 68.31 ? 12 PRO N C 1 +ATOM 24832 O O . PRO N 1 12 ? 41.052 42.096 80.814 1.00 61.76 ? 12 PRO N O 1 +ATOM 24833 C CB . PRO N 1 12 ? 42.602 41.629 78.371 1.00 74.99 ? 12 PRO N CB 1 +ATOM 24834 C CG . PRO N 1 12 ? 44.002 42.137 78.346 1.00 79.21 ? 12 PRO N CG 1 +ATOM 24835 C CD . PRO N 1 12 ? 43.986 43.343 79.232 1.00 105.37 ? 12 PRO N CD 1 +ATOM 24836 N N . THR N 1 13 ? 39.438 42.895 79.501 1.00 81.72 ? 13 THR N N 1 +ATOM 24837 C CA . THR N 1 13 ? 38.338 42.424 80.324 1.00 105.82 ? 13 THR N CA 1 +ATOM 24838 C C . THR N 1 13 ? 37.712 41.158 79.730 1.00 104.10 ? 13 THR N C 1 +ATOM 24839 O O . THR N 1 13 ? 37.864 40.904 78.529 1.00 133.87 ? 13 THR N O 1 +ATOM 24840 C CB . THR N 1 13 ? 37.265 43.519 80.409 1.00 140.16 ? 13 THR N CB 1 +ATOM 24841 O OG1 . THR N 1 13 ? 36.298 43.162 81.402 1.00 245.30 ? 13 THR N OG1 1 +ATOM 24842 C CG2 . THR N 1 13 ? 36.567 43.778 79.027 1.00 107.22 ? 13 THR N CG2 1 +ATOM 24843 N N . LEU N 1 14 ? 36.970 40.385 80.516 1.00 79.96 ? 14 LEU N N 1 +ATOM 24844 C CA . LEU N 1 14 ? 36.133 39.372 79.873 1.00 81.60 ? 14 LEU N CA 1 +ATOM 24845 C C . LEU N 1 14 ? 34.946 40.049 79.163 1.00 83.34 ? 14 LEU N C 1 +ATOM 24846 O O . LEU N 1 14 ? 34.633 41.181 79.455 1.00 77.12 ? 14 LEU N O 1 +ATOM 24847 C CB . LEU N 1 14 ? 35.719 38.247 80.818 1.00 80.64 ? 14 LEU N CB 1 +ATOM 24848 C CG . LEU N 1 14 ? 35.044 38.611 82.114 1.00 103.69 ? 14 LEU N CG 1 +ATOM 24849 C CD1 . LEU N 1 14 ? 34.039 37.537 82.519 1.00 115.30 ? 14 LEU N CD1 1 +ATOM 24850 C CD2 . LEU N 1 14 ? 36.106 38.764 83.178 1.00 117.59 ? 14 LEU N CD2 1 +ATOM 24851 N N . MET N 1 15 ? 34.316 39.387 78.193 1.00 101.70 ? 15 MET N N 1 +ATOM 24852 C CA . MET N 1 15 ? 33.545 40.112 77.166 1.00 98.64 ? 15 MET N CA 1 +ATOM 24853 C C . MET N 1 15 ? 32.275 40.745 77.761 1.00 100.63 ? 15 MET N C 1 +ATOM 24854 O O . MET N 1 15 ? 31.438 40.039 78.337 1.00 133.21 ? 15 MET N O 1 +ATOM 24855 C CB . MET N 1 15 ? 33.184 39.201 75.966 1.00 111.63 ? 15 MET N CB 1 +ATOM 24856 C CG . MET N 1 15 ? 33.057 39.960 74.644 1.00 118.41 ? 15 MET N CG 1 +ATOM 24857 S SD . MET N 1 15 ? 31.879 39.427 73.374 1.00 140.29 ? 15 MET N SD 1 +ATOM 24858 C CE . MET N 1 15 ? 30.613 38.495 74.255 1.00 109.84 ? 15 MET N CE 1 +ATOM 24859 N N . PRO N 1 16 ? 32.115 42.068 77.592 1.00 79.51 ? 16 PRO N N 1 +ATOM 24860 C CA . PRO N 1 16 ? 31.084 42.865 78.246 1.00 75.86 ? 16 PRO N CA 1 +ATOM 24861 C C . PRO N 1 16 ? 29.667 42.515 77.803 1.00 79.85 ? 16 PRO N C 1 +ATOM 24862 O O . PRO N 1 16 ? 29.071 43.207 76.972 1.00 105.69 ? 16 PRO N O 1 +ATOM 24863 C CB . PRO N 1 16 ? 31.451 44.298 77.852 1.00 81.53 ? 16 PRO N CB 1 +ATOM 24864 C CG . PRO N 1 16 ? 32.238 44.145 76.601 1.00 88.44 ? 16 PRO N CG 1 +ATOM 24865 C CD . PRO N 1 16 ? 33.016 42.894 76.782 1.00 83.20 ? 16 PRO N CD 1 +ATOM 24866 N N . ARG N 1 17 ? 29.098 41.486 78.415 1.00 87.77 ? 17 ARG N N 1 +ATOM 24867 C CA . ARG N 1 17 ? 27.689 41.144 78.200 1.00 122.12 ? 17 ARG N CA 1 +ATOM 24868 C C . ARG N 1 17 ? 26.829 41.898 79.212 1.00 150.13 ? 17 ARG N C 1 +ATOM 24869 O O . ARG N 1 17 ? 27.274 42.140 80.331 1.00 188.30 ? 17 ARG N O 1 +ATOM 24870 C CB . ARG N 1 17 ? 27.493 39.639 78.358 1.00 132.68 ? 17 ARG N CB 1 +ATOM 24871 C CG . ARG N 1 17 ? 27.726 38.865 77.078 1.00 145.01 ? 17 ARG N CG 1 +ATOM 24872 C CD . ARG N 1 17 ? 27.955 37.379 77.319 1.00 152.63 ? 17 ARG N CD 1 +ATOM 24873 N NE . ARG N 1 17 ? 29.308 37.101 77.801 1.00 167.87 ? 17 ARG N NE 1 +ATOM 24874 C CZ . ARG N 1 17 ? 29.728 35.903 78.198 1.00 174.74 ? 17 ARG N CZ 1 +ATOM 24875 N NH1 . ARG N 1 17 ? 28.877 34.880 78.202 1.00 168.56 ? 17 ARG N NH1 1 +ATOM 24876 N NH2 . ARG N 1 17 ? 30.993 35.729 78.588 1.00 160.44 ? 17 ARG N NH2 1 +ATOM 24877 N N . ALA N 1 18 ? 25.611 42.285 78.830 1.00 148.62 ? 18 ALA N N 1 +ATOM 24878 C CA . ALA N 1 18 ? 24.752 43.087 79.718 1.00 127.81 ? 18 ALA N CA 1 +ATOM 24879 C C . ALA N 1 18 ? 23.495 42.332 80.184 1.00 139.53 ? 18 ALA N C 1 +ATOM 24880 O O . ALA N 1 18 ? 23.607 41.321 80.892 1.00 135.75 ? 18 ALA N O 1 +ATOM 24881 C CB . ALA N 1 18 ? 24.384 44.413 79.068 1.00 122.19 ? 18 ALA N CB 1 +ATOM 24882 N N . GLN N 1 19 ? 22.312 42.847 79.847 1.00 133.27 ? 19 GLN N N 1 +ATOM 24883 C CA . GLN N 1 19 ? 21.096 42.498 80.586 1.00 158.47 ? 19 GLN N CA 1 +ATOM 24884 C C . GLN N 1 19 ? 20.665 41.067 80.295 1.00 146.90 ? 19 GLN N C 1 +ATOM 24885 O O . GLN N 1 19 ? 20.366 40.275 81.214 1.00 121.12 ? 19 GLN N O 1 +ATOM 24886 C CB . GLN N 1 19 ? 19.961 43.466 80.231 1.00 178.19 ? 19 GLN N CB 1 +ATOM 24887 C CG . GLN N 1 19 ? 18.686 43.268 81.044 1.00 199.00 ? 19 GLN N CG 1 +ATOM 24888 C CD . GLN N 1 19 ? 18.929 43.316 82.548 1.00 172.94 ? 19 GLN N CD 1 +ATOM 24889 O OE1 . GLN N 1 19 ? 19.285 44.358 83.096 1.00 156.77 ? 19 GLN N OE1 1 +ATOM 24890 N NE2 . GLN N 1 19 ? 18.747 42.180 83.216 1.00 147.15 ? 19 GLN N NE2 1 +ATOM 24891 N N . SER N 1 20 ? 20.585 40.769 79.004 1.00 122.13 ? 20 SER N N 1 +ATOM 24892 C CA . SER N 1 20 ? 20.321 39.426 78.535 1.00 142.31 ? 20 SER N CA 1 +ATOM 24893 C C . SER N 1 20 ? 21.114 38.388 79.351 1.00 165.51 ? 20 SER N C 1 +ATOM 24894 O O . SER N 1 20 ? 20.552 37.393 79.826 1.00 141.96 ? 20 SER N O 1 +ATOM 24895 C CB . SER N 1 20 ? 20.688 39.342 77.049 1.00 139.59 ? 20 SER N CB 1 +ATOM 24896 O OG . SER N 1 20 ? 20.080 40.396 76.320 1.00 123.39 ? 20 SER N OG 1 +ATOM 24897 N N . TYR N 1 21 ? 22.420 38.622 79.485 1.00 173.24 ? 21 TYR N N 1 +ATOM 24898 C CA . TYR N 1 21 ? 23.304 37.747 80.256 1.00 166.24 ? 21 TYR N CA 1 +ATOM 24899 C C . TYR N 1 21 ? 22.836 37.575 81.699 1.00 150.45 ? 21 TYR N C 1 +ATOM 24900 O O . TYR N 1 21 ? 22.761 36.446 82.213 1.00 151.53 ? 21 TYR N O 1 +ATOM 24901 C CB . TYR N 1 21 ? 24.732 38.297 80.247 1.00 165.50 ? 21 TYR N CB 1 +ATOM 24902 C CG . TYR N 1 21 ? 25.718 37.422 80.998 1.00 163.02 ? 21 TYR N CG 1 +ATOM 24903 C CD1 . TYR N 1 21 ? 26.196 36.236 80.434 1.00 144.51 ? 21 TYR N CD1 1 +ATOM 24904 C CD2 . TYR N 1 21 ? 26.158 37.772 82.274 1.00 146.26 ? 21 TYR N CD2 1 +ATOM 24905 C CE1 . TYR N 1 21 ? 27.085 35.438 81.109 1.00 126.04 ? 21 TYR N CE1 1 +ATOM 24906 C CE2 . TYR N 1 21 ? 27.063 36.981 82.959 1.00 131.22 ? 21 TYR N CE2 1 +ATOM 24907 C CZ . TYR N 1 21 ? 27.523 35.821 82.369 1.00 132.69 ? 21 TYR N CZ 1 +ATOM 24908 O OH . TYR N 1 21 ? 28.427 35.018 83.019 1.00 146.95 ? 21 TYR N OH 1 +ATOM 24909 N N . LYS N 1 22 ? 22.548 38.695 82.354 1.00 124.81 ? 22 LYS N N 1 +ATOM 24910 C CA . LYS N 1 22 ? 22.152 38.679 83.757 1.00 132.91 ? 22 LYS N CA 1 +ATOM 24911 C C . LYS N 1 22 ? 20.881 37.868 83.975 1.00 133.55 ? 22 LYS N C 1 +ATOM 24912 O O . LYS N 1 22 ? 20.758 37.138 84.967 1.00 132.62 ? 22 LYS N O 1 +ATOM 24913 C CB . LYS N 1 22 ? 21.952 40.106 84.262 1.00 144.46 ? 22 LYS N CB 1 +ATOM 24914 C CG . LYS N 1 22 ? 23.217 40.738 84.812 1.00 157.28 ? 22 LYS N CG 1 +ATOM 24915 C CD . LYS N 1 22 ? 23.449 40.291 86.261 1.00 171.14 ? 22 LYS N CD 1 +ATOM 24916 C CE . LYS N 1 22 ? 23.033 41.404 87.229 1.00 179.39 ? 22 LYS N CE 1 +ATOM 24917 N NZ . LYS N 1 22 ? 23.899 42.604 87.083 1.00 181.50 ? 22 LYS N NZ 1 +ATOM 24918 N N . ASP N 1 23 ? 19.933 38.017 83.056 1.00 140.38 ? 23 ASP N N 1 +ATOM 24919 C CA . ASP N 1 23 ? 18.707 37.218 83.076 1.00 148.61 ? 23 ASP N CA 1 +ATOM 24920 C C . ASP N 1 23 ? 19.024 35.745 82.858 1.00 136.23 ? 23 ASP N C 1 +ATOM 24921 O O . ASP N 1 23 ? 18.495 34.872 83.559 1.00 162.81 ? 23 ASP N O 1 +ATOM 24922 C CB . ASP N 1 23 ? 17.742 37.696 81.988 1.00 140.81 ? 23 ASP N CB 1 +ATOM 24923 C CG . ASP N 1 23 ? 17.197 39.066 82.265 1.00 162.01 ? 23 ASP N CG 1 +ATOM 24924 O OD1 . ASP N 1 23 ? 16.861 39.335 83.438 1.00 187.58 ? 23 ASP N OD1 1 +ATOM 24925 O OD2 . ASP N 1 23 ? 17.088 39.873 81.313 1.00 186.91 ? 23 ASP N OD2 1 +ATOM 24926 N N . LEU N 1 24 ? 19.882 35.486 81.877 1.00 118.32 ? 24 LEU N N 1 +ATOM 24927 C CA . LEU N 1 24 ? 20.194 34.127 81.446 1.00 139.10 ? 24 LEU N CA 1 +ATOM 24928 C C . LEU N 1 24 ? 20.888 33.318 82.548 1.00 153.23 ? 24 LEU N C 1 +ATOM 24929 O O . LEU N 1 24 ? 20.670 32.094 82.678 1.00 140.41 ? 24 LEU N O 1 +ATOM 24930 C CB . LEU N 1 24 ? 21.080 34.177 80.194 1.00 134.16 ? 24 LEU N CB 1 +ATOM 24931 C CG . LEU N 1 24 ? 21.520 32.846 79.566 1.00 132.84 ? 24 LEU N CG 1 +ATOM 24932 C CD1 . LEU N 1 24 ? 20.472 32.315 78.595 1.00 122.10 ? 24 LEU N CD1 1 +ATOM 24933 C CD2 . LEU N 1 24 ? 22.855 33.022 78.860 1.00 142.35 ? 24 LEU N CD2 1 +ATOM 24934 N N . THR N 1 25 ? 21.728 33.999 83.330 1.00 164.97 ? 25 THR N N 1 +ATOM 24935 C CA . THR N 1 25 ? 22.511 33.341 84.389 1.00 169.04 ? 25 THR N CA 1 +ATOM 24936 C C . THR N 1 25 ? 21.664 33.022 85.620 1.00 177.41 ? 25 THR N C 1 +ATOM 24937 O O . THR N 1 25 ? 21.689 31.892 86.128 1.00 170.73 ? 25 THR N O 1 +ATOM 24938 C CB . THR N 1 25 ? 23.709 34.205 84.826 1.00 140.68 ? 25 THR N CB 1 +ATOM 24939 O OG1 . THR N 1 25 ? 23.284 35.557 85.010 1.00 142.84 ? 25 THR N OG1 1 +ATOM 24940 C CG2 . THR N 1 25 ? 24.793 34.164 83.770 1.00 146.23 ? 25 THR N CG2 1 +ATOM 24941 N N . HIS N 1 26 ? 20.868 33.999 86.048 1.00 186.39 ? 26 HIS N N 1 +ATOM 24942 C CA . HIS N 1 26 ? 20.018 33.861 87.234 1.00 187.59 ? 26 HIS N CA 1 +ATOM 24943 C C . HIS N 1 26 ? 18.674 33.176 86.911 1.00 156.91 ? 26 HIS N C 1 +ATOM 24944 O O . HIS N 1 26 ? 17.633 33.514 87.467 1.00 125.49 ? 26 HIS N O 1 +ATOM 24945 C CB . HIS N 1 26 ? 19.799 35.241 87.880 1.00 201.29 ? 26 HIS N CB 1 +ATOM 24946 C CG . HIS N 1 26 ? 21.064 35.875 88.391 1.00 200.13 ? 26 HIS N CG 1 +ATOM 24947 N ND1 . HIS N 1 26 ? 22.059 36.338 87.554 1.00 198.46 ? 26 HIS N ND1 1 +ATOM 24948 C CD2 . HIS N 1 26 ? 21.503 36.104 89.652 1.00 192.49 ? 26 HIS N CD2 1 +ATOM 24949 C CE1 . HIS N 1 26 ? 23.048 36.835 88.276 1.00 186.08 ? 26 HIS N CE1 1 +ATOM 24950 N NE2 . HIS N 1 26 ? 22.738 36.701 89.553 1.00 187.53 ? 26 HIS N NE2 1 +ATOM 24951 N N . LEU N 1 27 ? 18.698 32.209 86.004 1.00 131.93 ? 27 LEU N N 1 +ATOM 24952 C CA . LEU N 1 27 ? 17.508 31.426 85.708 1.00 120.61 ? 27 LEU N CA 1 +ATOM 24953 C C . LEU N 1 27 ? 17.441 30.248 86.678 1.00 115.58 ? 27 LEU N C 1 +ATOM 24954 O O . LEU N 1 27 ? 18.432 29.543 86.863 1.00 134.92 ? 27 LEU N O 1 +ATOM 24955 C CB . LEU N 1 27 ? 17.524 30.935 84.245 1.00 122.52 ? 27 LEU N CB 1 +ATOM 24956 C CG . LEU N 1 27 ? 16.919 31.900 83.222 1.00 138.80 ? 27 LEU N CG 1 +ATOM 24957 C CD1 . LEU N 1 27 ? 17.266 31.481 81.804 1.00 156.42 ? 27 LEU N CD1 1 +ATOM 24958 C CD2 . LEU N 1 27 ? 15.409 31.998 83.385 1.00 144.90 ? 27 LEU N CD2 1 +ATOM 24959 N N . PRO N 1 28 ? 16.253 29.980 87.235 1.00 107.63 ? 28 PRO N N 1 +ATOM 24960 C CA . PRO N 1 28 ? 16.058 28.817 88.103 1.00 105.84 ? 28 PRO N CA 1 +ATOM 24961 C C . PRO N 1 28 ? 16.420 27.497 87.432 1.00 100.90 ? 28 PRO N C 1 +ATOM 24962 O O . PRO N 1 28 ? 15.927 27.208 86.349 1.00 127.95 ? 28 PRO N O 1 +ATOM 24963 C CB . PRO N 1 28 ? 14.553 28.853 88.403 1.00 134.23 ? 28 PRO N CB 1 +ATOM 24964 C CG . PRO N 1 28 ? 13.942 29.589 87.249 1.00 129.37 ? 28 PRO N CG 1 +ATOM 24965 C CD . PRO N 1 28 ? 14.973 30.603 86.845 1.00 122.19 ? 28 PRO N CD 1 +ATOM 24966 N N . ALA N 1 29 ? 17.237 26.684 88.088 1.00 106.78 ? 29 ALA N N 1 +ATOM 24967 C CA . ALA N 1 29 ? 17.828 25.505 87.442 1.00 106.56 ? 29 ALA N CA 1 +ATOM 24968 C C . ALA N 1 29 ? 16.800 24.368 87.217 1.00 111.69 ? 29 ALA N C 1 +ATOM 24969 O O . ALA N 1 29 ? 15.854 24.203 87.997 1.00 135.93 ? 29 ALA N O 1 +ATOM 24970 C CB . ALA N 1 29 ? 19.039 25.013 88.240 1.00 95.02 ? 29 ALA N CB 1 +ATOM 24971 N N . PRO N 1 30 ? 16.954 23.609 86.119 1.00 103.21 ? 30 PRO N N 1 +ATOM 24972 C CA . PRO N 1 30 ? 16.142 22.419 85.837 1.00 104.66 ? 30 PRO N CA 1 +ATOM 24973 C C . PRO N 1 30 ? 16.521 21.210 86.704 1.00 97.02 ? 30 PRO N C 1 +ATOM 24974 O O . PRO N 1 30 ? 17.505 21.274 87.456 1.00 64.92 ? 30 PRO N O 1 +ATOM 24975 C CB . PRO N 1 30 ? 16.483 22.111 84.392 1.00 108.75 ? 30 PRO N CB 1 +ATOM 24976 C CG . PRO N 1 30 ? 17.888 22.579 84.241 1.00 130.83 ? 30 PRO N CG 1 +ATOM 24977 C CD . PRO N 1 30 ? 18.055 23.759 85.156 1.00 118.77 ? 30 PRO N CD 1 +ATOM 24978 N N . THR N 1 31 ? 15.765 20.116 86.573 1.00 97.75 ? 31 THR N N 1 +ATOM 24979 C CA . THR N 1 31 ? 16.017 18.907 87.374 1.00 132.34 ? 31 THR N CA 1 +ATOM 24980 C C . THR N 1 31 ? 17.340 18.218 87.012 1.00 133.66 ? 31 THR N C 1 +ATOM 24981 O O . THR N 1 31 ? 17.946 17.537 87.838 1.00 106.64 ? 31 THR N O 1 +ATOM 24982 C CB . THR N 1 31 ? 14.866 17.867 87.274 1.00 143.09 ? 31 THR N CB 1 +ATOM 24983 O OG1 . THR N 1 31 ? 14.574 17.565 85.907 1.00 122.23 ? 31 THR N OG1 1 +ATOM 24984 C CG2 . THR N 1 31 ? 13.607 18.380 87.958 1.00 152.29 ? 31 THR N CG2 1 +ATOM 24985 N N . GLY N 1 32 ? 17.765 18.380 85.767 1.00 147.39 ? 32 GLY N N 1 +ATOM 24986 C CA . GLY N 1 32 ? 19.116 18.009 85.352 1.00 157.62 ? 32 GLY N CA 1 +ATOM 24987 C C . GLY N 1 32 ? 19.483 18.818 84.123 1.00 153.21 ? 32 GLY N C 1 +ATOM 24988 O O . GLY N 1 32 ? 18.594 19.297 83.421 1.00 168.27 ? 32 GLY N O 1 +ATOM 24989 N N . LYS N 1 33 ? 20.775 19.035 83.885 1.00 122.53 ? 33 LYS N N 1 +ATOM 24990 C CA . LYS N 1 33 ? 21.173 19.754 82.690 1.00 103.08 ? 33 LYS N CA 1 +ATOM 24991 C C . LYS N 1 33 ? 20.865 18.914 81.445 1.00 110.71 ? 33 LYS N C 1 +ATOM 24992 O O . LYS N 1 33 ? 20.866 17.682 81.505 1.00 107.70 ? 33 LYS N O 1 +ATOM 24993 C CB . LYS N 1 33 ? 22.643 20.145 82.741 1.00 109.43 ? 33 LYS N CB 1 +ATOM 24994 C CG . LYS N 1 33 ? 22.868 21.519 83.364 1.00 102.11 ? 33 LYS N CG 1 +ATOM 24995 C CD . LYS N 1 33 ? 24.320 21.806 83.388 1.00 107.44 ? 33 LYS N CD 1 +ATOM 24996 C CE . LYS N 1 33 ? 24.925 21.154 84.581 1.00 113.05 ? 33 LYS N CE 1 +ATOM 24997 N NZ . LYS N 1 33 ? 26.284 20.667 84.273 1.00 130.26 ? 33 LYS N NZ 1 +ATOM 24998 N N . ILE N 1 34 ? 20.597 19.578 80.323 1.00 113.23 ? 34 ILE N N 1 +ATOM 24999 C CA . ILE N 1 34 ? 20.235 18.882 79.098 1.00 121.86 ? 34 ILE N CA 1 +ATOM 25000 C C . ILE N 1 34 ? 21.437 18.926 78.135 1.00 137.99 ? 34 ILE N C 1 +ATOM 25001 O O . ILE N 1 34 ? 22.209 19.895 78.131 1.00 128.57 ? 34 ILE N O 1 +ATOM 25002 C CB . ILE N 1 34 ? 18.924 19.468 78.503 1.00 132.93 ? 34 ILE N CB 1 +ATOM 25003 C CG1 . ILE N 1 34 ? 17.746 19.186 79.440 1.00 133.85 ? 34 ILE N CG1 1 +ATOM 25004 C CG2 . ILE N 1 34 ? 18.586 18.861 77.145 1.00 156.50 ? 34 ILE N CG2 1 +ATOM 25005 C CD1 . ILE N 1 34 ? 17.094 20.438 79.977 1.00 144.43 ? 34 ILE N CD1 1 +ATOM 25006 N N . PHE N 1 35 ? 21.644 17.820 77.416 1.00 129.68 ? 35 PHE N N 1 +ATOM 25007 C CA . PHE N 1 35 ? 22.732 17.679 76.455 1.00 105.03 ? 35 PHE N CA 1 +ATOM 25008 C C . PHE N 1 35 ? 22.337 18.304 75.133 1.00 109.54 ? 35 PHE N C 1 +ATOM 25009 O O . PHE N 1 35 ? 21.344 17.890 74.528 1.00 133.65 ? 35 PHE N O 1 +ATOM 25010 C CB . PHE N 1 35 ? 22.996 16.198 76.204 1.00 110.20 ? 35 PHE N CB 1 +ATOM 25011 C CG . PHE N 1 35 ? 23.930 15.566 77.186 1.00 99.67 ? 35 PHE N CG 1 +ATOM 25012 C CD1 . PHE N 1 35 ? 25.085 16.217 77.590 1.00 75.47 ? 35 PHE N CD1 1 +ATOM 25013 C CD2 . PHE N 1 35 ? 23.690 14.265 77.629 1.00 92.78 ? 35 PHE N CD2 1 +ATOM 25014 C CE1 . PHE N 1 35 ? 25.954 15.602 78.463 1.00 93.16 ? 35 PHE N CE1 1 +ATOM 25015 C CE2 . PHE N 1 35 ? 24.565 13.643 78.492 1.00 92.03 ? 35 PHE N CE2 1 +ATOM 25016 C CZ . PHE N 1 35 ? 25.696 14.314 78.918 1.00 100.40 ? 35 PHE N CZ 1 +ATOM 25017 N N . VAL N 1 36 ? 23.152 19.230 74.631 1.00 102.05 ? 36 VAL N N 1 +ATOM 25018 C CA . VAL N 1 36 ? 22.800 19.929 73.400 1.00 84.44 ? 36 VAL N CA 1 +ATOM 25019 C C . VAL N 1 36 ? 23.933 19.989 72.388 1.00 102.53 ? 36 VAL N C 1 +ATOM 25020 O O . VAL N 1 36 ? 25.113 19.944 72.737 1.00 142.24 ? 36 VAL N O 1 +ATOM 25021 C CB . VAL N 1 36 ? 22.365 21.342 73.715 1.00 79.45 ? 36 VAL N CB 1 +ATOM 25022 C CG1 . VAL N 1 36 ? 23.566 22.221 74.053 1.00 81.13 ? 36 VAL N CG1 1 +ATOM 25023 C CG2 . VAL N 1 36 ? 21.597 21.905 72.549 1.00 90.61 ? 36 VAL N CG2 1 +ATOM 25024 N N . SER N 1 37 ? 23.569 20.035 71.120 1.00 93.50 ? 37 SER N N 1 +ATOM 25025 C CA . SER N 1 37 ? 24.554 20.082 70.059 1.00 104.18 ? 37 SER N CA 1 +ATOM 25026 C C . SER N 1 37 ? 24.296 21.354 69.274 1.00 92.71 ? 37 SER N C 1 +ATOM 25027 O O . SER N 1 37 ? 23.196 21.576 68.814 1.00 68.49 ? 37 SER N O 1 +ATOM 25028 C CB . SER N 1 37 ? 24.405 18.862 69.133 1.00 94.98 ? 37 SER N CB 1 +ATOM 25029 O OG . SER N 1 37 ? 24.911 17.688 69.718 1.00 65.63 ? 37 SER N OG 1 +ATOM 25030 N N . VAL N 1 38 ? 25.345 22.104 68.980 1.00 93.67 ? 38 VAL N N 1 +ATOM 25031 C CA . VAL N 1 38 ? 25.247 23.121 67.930 1.00 88.14 ? 38 VAL N CA 1 +ATOM 25032 C C . VAL N 1 38 ? 26.285 22.874 66.821 1.00 95.29 ? 38 VAL N C 1 +ATOM 25033 O O . VAL N 1 38 ? 27.491 22.875 67.092 1.00 121.84 ? 38 VAL N O 1 +ATOM 25034 C CB . VAL N 1 38 ? 25.497 24.522 68.491 1.00 71.68 ? 38 VAL N CB 1 +ATOM 25035 C CG1 . VAL N 1 38 ? 25.428 25.547 67.380 1.00 60.13 ? 38 VAL N CG1 1 +ATOM 25036 C CG2 . VAL N 1 38 ? 24.515 24.848 69.596 1.00 71.75 ? 38 VAL N CG2 1 +ATOM 25037 N N . TYR N 1 39 ? 25.804 22.684 65.594 1.00 84.58 ? 39 TYR N N 1 +ATOM 25038 C CA . TYR N 1 39 ? 26.656 22.401 64.455 1.00 83.05 ? 39 TYR N CA 1 +ATOM 25039 C C . TYR N 1 39 ? 27.050 23.721 63.796 1.00 90.70 ? 39 TYR N C 1 +ATOM 25040 O O . TYR N 1 39 ? 28.230 23.989 63.582 1.00 112.31 ? 39 TYR N O 1 +ATOM 25041 C CB . TYR N 1 39 ? 25.949 21.440 63.470 1.00 87.24 ? 39 TYR N CB 1 +ATOM 25042 C CG . TYR N 1 39 ? 26.132 19.974 63.839 1.00 98.16 ? 39 TYR N CG 1 +ATOM 25043 C CD1 . TYR N 1 39 ? 25.410 19.386 64.872 1.00 71.76 ? 39 TYR N CD1 1 +ATOM 25044 C CD2 . TYR N 1 39 ? 27.065 19.178 63.158 1.00 148.77 ? 39 TYR N CD2 1 +ATOM 25045 C CE1 . TYR N 1 39 ? 25.594 18.059 65.196 1.00 83.16 ? 39 TYR N CE1 1 +ATOM 25046 C CE2 . TYR N 1 39 ? 27.266 17.835 63.479 1.00 155.36 ? 39 TYR N CE2 1 +ATOM 25047 C CZ . TYR N 1 39 ? 26.537 17.280 64.512 1.00 120.61 ? 39 TYR N CZ 1 +ATOM 25048 O OH . TYR N 1 39 ? 26.771 15.942 64.838 1.00 100.96 ? 39 TYR N OH 1 +ATOM 25049 N N . ASN N 1 40 ? 26.069 24.546 63.447 1.00 99.70 ? 40 ASN N N 1 +ATOM 25050 C CA . ASN N 1 40 ? 26.358 25.811 62.762 1.00 98.15 ? 40 ASN N CA 1 +ATOM 25051 C C . ASN N 1 40 ? 25.190 26.793 62.684 1.00 93.92 ? 40 ASN N C 1 +ATOM 25052 O O . ASN N 1 40 ? 24.061 26.412 62.351 1.00 78.29 ? 40 ASN N O 1 +ATOM 25053 C CB . ASN N 1 40 ? 26.813 25.543 61.338 1.00 105.99 ? 40 ASN N CB 1 +ATOM 25054 C CG . ASN N 1 40 ? 27.544 26.724 60.745 1.00 134.54 ? 40 ASN N CG 1 +ATOM 25055 O OD1 . ASN N 1 40 ? 27.101 27.316 59.764 1.00 139.14 ? 40 ASN N OD1 1 +ATOM 25056 N ND2 . ASN N 1 40 ? 28.681 27.075 61.343 1.00 163.28 ? 40 ASN N ND2 1 +ATOM 25057 N N . ILE N 1 41 ? 25.455 28.053 63.024 1.00 95.76 ? 41 ILE N N 1 +ATOM 25058 C CA . ILE N 1 41 ? 24.483 29.126 62.816 1.00 97.91 ? 41 ILE N CA 1 +ATOM 25059 C C . ILE N 1 41 ? 25.072 30.120 61.821 1.00 114.61 ? 41 ILE N C 1 +ATOM 25060 O O . ILE N 1 41 ? 26.095 30.750 62.102 1.00 119.65 ? 41 ILE N O 1 +ATOM 25061 C CB . ILE N 1 41 ? 24.116 29.855 64.129 1.00 77.63 ? 41 ILE N CB 1 +ATOM 25062 C CG1 . ILE N 1 41 ? 23.067 29.074 64.921 1.00 89.33 ? 41 ILE N CG1 1 +ATOM 25063 C CG2 . ILE N 1 41 ? 23.488 31.199 63.818 1.00 75.58 ? 41 ILE N CG2 1 +ATOM 25064 C CD1 . ILE N 1 41 ? 23.554 27.792 65.558 1.00 102.08 ? 41 ILE N CD1 1 +ATOM 25065 N N . GLN N 1 42 ? 24.431 30.264 60.660 1.00 116.46 ? 42 GLN N N 1 +ATOM 25066 C CA . GLN N 1 42 ? 25.034 31.005 59.540 1.00 105.01 ? 42 GLN N CA 1 +ATOM 25067 C C . GLN N 1 42 ? 24.698 32.489 59.560 1.00 74.72 ? 42 GLN N C 1 +ATOM 25068 O O . GLN N 1 42 ? 23.682 32.878 60.100 1.00 58.88 ? 42 GLN N O 1 +ATOM 25069 C CB . GLN N 1 42 ? 24.594 30.431 58.194 1.00 113.35 ? 42 GLN N CB 1 +ATOM 25070 C CG . GLN N 1 42 ? 25.029 29.013 57.925 1.00 129.10 ? 42 GLN N CG 1 +ATOM 25071 C CD . GLN N 1 42 ? 23.798 28.116 57.749 1.00 147.48 ? 42 GLN N CD 1 +ATOM 25072 O OE1 . GLN N 1 42 ? 23.394 27.848 56.631 1.00 144.98 ? 42 GLN N OE1 1 +ATOM 25073 N NE2 . GLN N 1 42 ? 23.286 27.561 58.857 1.00 141.56 ? 42 GLN N NE2 1 +ATOM 25074 N N . ASP N 1 43 ? 25.571 33.285 58.944 1.00 60.82 ? 43 ASP N N 1 +ATOM 25075 C CA . ASP N 1 43 ? 25.287 34.651 58.624 1.00 56.35 ? 43 ASP N CA 1 +ATOM 25076 C C . ASP N 1 43 ? 24.396 34.704 57.393 1.00 70.29 ? 43 ASP N C 1 +ATOM 25077 O O . ASP N 1 43 ? 24.790 35.268 56.352 1.00 67.30 ? 43 ASP N O 1 +ATOM 25078 C CB . ASP N 1 43 ? 26.569 35.411 58.341 1.00 60.61 ? 43 ASP N CB 1 +ATOM 25079 C CG . ASP N 1 43 ? 26.339 36.933 58.230 1.00 84.22 ? 43 ASP N CG 1 +ATOM 25080 O OD1 . ASP N 1 43 ? 25.714 37.510 59.156 1.00 121.66 ? 43 ASP N OD1 1 +ATOM 25081 O OD2 . ASP N 1 43 ? 26.864 37.591 57.298 1.00 68.62 ? 43 ASP N OD2 1 +ATOM 25082 N N . GLU N 1 44 ? 23.157 34.199 57.525 1.00 83.10 ? 44 GLU N N 1 +ATOM 25083 C CA . GLU N 1 44 ? 22.157 34.228 56.430 1.00 100.33 ? 44 GLU N CA 1 +ATOM 25084 C C . GLU N 1 44 ? 21.637 35.679 56.069 1.00 85.74 ? 44 GLU N C 1 +ATOM 25085 O O . GLU N 1 44 ? 20.670 35.830 55.284 1.00 45.68 ? 44 GLU N O 1 +ATOM 25086 C CB . GLU N 1 44 ? 20.956 33.301 56.755 1.00 101.71 ? 44 GLU N CB 1 +ATOM 25087 C CG . GLU N 1 44 ? 21.138 31.824 56.383 1.00 100.69 ? 44 GLU N CG 1 +ATOM 25088 C CD . GLU N 1 44 ? 19.939 30.906 56.734 1.00 96.65 ? 44 GLU N CD 1 +ATOM 25089 O OE1 . GLU N 1 44 ? 18.760 31.282 56.526 1.00 135.57 ? 44 GLU N OE1 1 +ATOM 25090 O OE2 . GLU N 1 44 ? 20.166 29.814 57.287 1.00 74.93 ? 44 GLU N OE2 1 +ATOM 25091 N N . THR N 1 45 ? 22.375 36.702 56.532 1.00 79.07 ? 45 THR N N 1 +ATOM 25092 C CA . THR N 1 45 ? 21.966 38.096 56.418 1.00 83.14 ? 45 THR N CA 1 +ATOM 25093 C C . THR N 1 45 ? 22.128 38.696 55.027 1.00 87.68 ? 45 THR N C 1 +ATOM 25094 O O . THR N 1 45 ? 21.230 39.377 54.543 1.00 88.44 ? 45 THR N O 1 +ATOM 25095 C CB . THR N 1 45 ? 22.658 39.001 57.466 1.00 71.90 ? 45 THR N CB 1 +ATOM 25096 O OG1 . THR N 1 45 ? 21.950 40.239 57.520 1.00 146.77 ? 45 THR N OG1 1 +ATOM 25097 C CG2 . THR N 1 45 ? 24.108 39.274 57.158 1.00 50.73 ? 45 THR N CG2 1 +ATOM 25098 N N . GLY N 1 46 ? 23.232 38.384 54.358 1.00 107.94 ? 46 GLY N N 1 +ATOM 25099 C CA . GLY N 1 46 ? 23.404 38.728 52.934 1.00 103.89 ? 46 GLY N CA 1 +ATOM 25100 C C . GLY N 1 46 ? 24.023 40.109 52.782 1.00 117.69 ? 46 GLY N C 1 +ATOM 25101 O O . GLY N 1 46 ? 23.952 40.763 51.723 1.00 142.93 ? 46 GLY N O 1 +ATOM 25102 N N . GLN N 1 47 ? 24.638 40.580 53.842 1.00 90.41 ? 47 GLN N N 1 +ATOM 25103 C CA . GLN N 1 47 ? 24.912 41.956 53.885 1.00 67.40 ? 47 GLN N CA 1 +ATOM 25104 C C . GLN N 1 47 ? 26.358 42.227 54.208 1.00 77.60 ? 47 GLN N C 1 +ATOM 25105 O O . GLN N 1 47 ? 27.007 41.580 55.057 1.00 91.59 ? 47 GLN N O 1 +ATOM 25106 C CB . GLN N 1 47 ? 23.999 42.567 54.873 1.00 59.18 ? 47 GLN N CB 1 +ATOM 25107 C CG . GLN N 1 47 ? 22.567 42.552 54.410 1.00 78.47 ? 47 GLN N CG 1 +ATOM 25108 C CD . GLN N 1 47 ? 22.387 43.114 53.016 1.00 116.40 ? 47 GLN N CD 1 +ATOM 25109 O OE1 . GLN N 1 47 ? 22.493 44.308 52.793 1.00 124.42 ? 47 GLN N OE1 1 +ATOM 25110 N NE2 . GLN N 1 47 ? 22.085 42.251 52.068 1.00 184.10 ? 47 GLN N NE2 1 +ATOM 25111 N N . PHE N 1 48 ? 26.881 43.214 53.499 1.00 83.71 ? 48 PHE N N 1 +ATOM 25112 C CA . PHE N 1 48 ? 28.245 43.686 53.696 1.00 79.88 ? 48 PHE N CA 1 +ATOM 25113 C C . PHE N 1 48 ? 28.243 45.181 54.016 1.00 82.18 ? 48 PHE N C 1 +ATOM 25114 O O . PHE N 1 48 ? 27.269 45.904 53.777 1.00 82.52 ? 48 PHE N O 1 +ATOM 25115 C CB . PHE N 1 48 ? 29.087 43.400 52.441 1.00 71.85 ? 48 PHE N CB 1 +ATOM 25116 C CG . PHE N 1 48 ? 29.283 41.961 52.206 1.00 57.01 ? 48 PHE N CG 1 +ATOM 25117 C CD1 . PHE N 1 48 ? 28.233 41.195 51.781 1.00 53.62 ? 48 PHE N CD1 1 +ATOM 25118 C CD2 . PHE N 1 48 ? 30.458 41.375 52.505 1.00 66.83 ? 48 PHE N CD2 1 +ATOM 25119 C CE1 . PHE N 1 48 ? 28.345 39.848 51.642 1.00 61.57 ? 48 PHE N CE1 1 +ATOM 25120 C CE2 . PHE N 1 48 ? 30.591 40.023 52.373 1.00 97.21 ? 48 PHE N CE2 1 +ATOM 25121 C CZ . PHE N 1 48 ? 29.537 39.259 51.912 1.00 89.15 ? 48 PHE N CZ 1 +ATOM 25122 N N . LYS N 1 49 ? 29.399 45.650 54.446 1.00 92.20 ? 49 LYS N N 1 +ATOM 25123 C CA . LYS N 1 49 ? 29.556 47.048 54.774 1.00 97.09 ? 49 LYS N CA 1 +ATOM 25124 C C . LYS N 1 49 ? 29.674 47.884 53.506 1.00 94.24 ? 49 LYS N C 1 +ATOM 25125 O O . LYS N 1 49 ? 30.239 47.442 52.495 1.00 89.15 ? 49 LYS N O 1 +ATOM 25126 C CB . LYS N 1 49 ? 30.773 47.240 55.690 1.00 116.91 ? 49 LYS N CB 1 +ATOM 25127 C CG . LYS N 1 49 ? 30.579 46.557 57.039 1.00 110.37 ? 49 LYS N CG 1 +ATOM 25128 C CD . LYS N 1 49 ? 31.618 46.846 58.107 1.00 123.50 ? 49 LYS N CD 1 +ATOM 25129 C CE . LYS N 1 49 ? 31.112 46.202 59.403 1.00 140.17 ? 49 LYS N CE 1 +ATOM 25130 N NZ . LYS N 1 49 ? 31.970 46.405 60.598 1.00 156.07 ? 49 LYS N NZ 1 +ATOM 25131 N N . PRO N 1 50 ? 29.151 49.111 53.568 1.00 95.79 ? 50 PRO N N 1 +ATOM 25132 C CA . PRO N 1 50 ? 29.224 50.033 52.448 1.00 113.77 ? 50 PRO N CA 1 +ATOM 25133 C C . PRO N 1 50 ? 30.589 50.720 52.319 1.00 97.57 ? 50 PRO N C 1 +ATOM 25134 O O . PRO N 1 50 ? 31.408 50.668 53.240 1.00 85.73 ? 50 PRO N O 1 +ATOM 25135 C CB . PRO N 1 50 ? 28.124 51.057 52.771 1.00 117.89 ? 50 PRO N CB 1 +ATOM 25136 C CG . PRO N 1 50 ? 28.049 51.061 54.253 1.00 103.58 ? 50 PRO N CG 1 +ATOM 25137 C CD . PRO N 1 50 ? 28.369 49.659 54.689 1.00 95.31 ? 50 PRO N CD 1 +ATOM 25138 N N . TYR N 1 51 ? 30.805 51.367 51.175 1.00 87.14 ? 51 TYR N N 1 +ATOM 25139 C CA . TYR N 1 51 ? 31.952 52.222 51.010 1.00 73.51 ? 51 TYR N CA 1 +ATOM 25140 C C . TYR N 1 51 ? 32.055 53.164 52.203 1.00 70.69 ? 51 TYR N C 1 +ATOM 25141 O O . TYR N 1 51 ? 31.054 53.738 52.634 1.00 65.33 ? 51 TYR N O 1 +ATOM 25142 C CB . TYR N 1 51 ? 31.859 53.028 49.716 1.00 73.46 ? 51 TYR N CB 1 +ATOM 25143 C CG . TYR N 1 51 ? 33.185 53.639 49.353 1.00 68.35 ? 51 TYR N CG 1 +ATOM 25144 C CD1 . TYR N 1 51 ? 34.073 52.942 48.594 1.00 78.81 ? 51 TYR N CD1 1 +ATOM 25145 C CD2 . TYR N 1 51 ? 33.534 54.926 49.757 1.00 81.83 ? 51 TYR N CD2 1 +ATOM 25146 C CE1 . TYR N 1 51 ? 35.312 53.462 48.278 1.00 103.03 ? 51 TYR N CE1 1 +ATOM 25147 C CE2 . TYR N 1 51 ? 34.761 55.487 49.398 1.00 95.35 ? 51 TYR N CE2 1 +ATOM 25148 C CZ . TYR N 1 51 ? 35.664 54.714 48.693 1.00 105.78 ? 51 TYR N CZ 1 +ATOM 25149 O OH . TYR N 1 51 ? 36.918 55.170 48.342 1.00 115.06 ? 51 TYR N OH 1 +ATOM 25150 N N . PRO N 1 52 ? 33.265 53.338 52.750 1.00 83.38 ? 52 PRO N N 1 +ATOM 25151 C CA . PRO N 1 52 ? 34.575 52.868 52.270 1.00 110.43 ? 52 PRO N CA 1 +ATOM 25152 C C . PRO N 1 52 ? 35.084 51.532 52.798 1.00 129.45 ? 52 PRO N C 1 +ATOM 25153 O O . PRO N 1 52 ? 36.295 51.276 52.704 1.00 117.21 ? 52 PRO N O 1 +ATOM 25154 C CB . PRO N 1 52 ? 35.519 53.974 52.748 1.00 117.30 ? 52 PRO N CB 1 +ATOM 25155 C CG . PRO N 1 52 ? 34.906 54.416 54.043 1.00 113.81 ? 52 PRO N CG 1 +ATOM 25156 C CD . PRO N 1 52 ? 33.411 54.281 53.875 1.00 88.97 ? 52 PRO N CD 1 +ATOM 25157 N N . ALA N 1 53 ? 34.204 50.691 53.348 1.00 122.93 ? 53 ALA N N 1 +ATOM 25158 C CA . ALA N 1 53 ? 34.644 49.386 53.827 1.00 117.04 ? 53 ALA N CA 1 +ATOM 25159 C C . ALA N 1 53 ? 35.117 48.553 52.657 1.00 120.95 ? 53 ALA N C 1 +ATOM 25160 O O . ALA N 1 53 ? 34.771 48.810 51.485 1.00 86.41 ? 53 ALA N O 1 +ATOM 25161 C CB . ALA N 1 53 ? 33.536 48.658 54.565 1.00 125.10 ? 53 ALA N CB 1 +ATOM 25162 N N . SER N 1 54 ? 35.921 47.543 52.961 1.00 116.11 ? 54 SER N N 1 +ATOM 25163 C CA . SER N 1 54 ? 36.219 46.572 51.928 1.00 90.77 ? 54 SER N CA 1 +ATOM 25164 C C . SER N 1 54 ? 34.900 45.990 51.421 1.00 72.48 ? 54 SER N C 1 +ATOM 25165 O O . SER N 1 54 ? 33.976 45.703 52.217 1.00 73.14 ? 54 SER N O 1 +ATOM 25166 C CB . SER N 1 54 ? 37.162 45.476 52.438 1.00 96.43 ? 54 SER N CB 1 +ATOM 25167 O OG . SER N 1 54 ? 37.093 44.288 51.634 1.00 62.76 ? 54 SER N OG 1 +ATOM 25168 N N . ASN N 1 55 ? 34.856 45.767 50.111 1.00 49.97 ? 55 ASN N N 1 +ATOM 25169 C CA . ASN N 1 55 ? 33.797 45.017 49.484 1.00 48.63 ? 55 ASN N CA 1 +ATOM 25170 C C . ASN N 1 55 ? 33.407 43.721 50.239 1.00 65.21 ? 55 ASN N C 1 +ATOM 25171 O O . ASN N 1 55 ? 32.239 43.295 50.292 1.00 47.19 ? 55 ASN N O 1 +ATOM 25172 C CB . ASN N 1 55 ? 34.219 44.651 48.094 1.00 42.24 ? 55 ASN N CB 1 +ATOM 25173 C CG . ASN N 1 55 ? 33.069 44.254 47.250 1.00 73.99 ? 55 ASN N CG 1 +ATOM 25174 O OD1 . ASN N 1 55 ? 31.897 44.566 47.533 1.00 161.77 ? 55 ASN N OD1 1 +ATOM 25175 N ND2 . ASN N 1 55 ? 33.377 43.658 46.133 1.00 100.59 ? 55 ASN N ND2 1 +ATOM 25176 N N . PHE N 1 56 ? 34.394 43.133 50.907 1.00 93.12 ? 56 PHE N N 1 +ATOM 25177 C CA . PHE N 1 56 ? 34.257 41.814 51.539 1.00 90.55 ? 56 PHE N CA 1 +ATOM 25178 C C . PHE N 1 56 ? 34.007 41.862 53.042 1.00 97.93 ? 56 PHE N C 1 +ATOM 25179 O O . PHE N 1 56 ? 33.923 40.822 53.690 1.00 105.83 ? 56 PHE N O 1 +ATOM 25180 C CB . PHE N 1 56 ? 35.524 41.005 51.328 1.00 80.66 ? 56 PHE N CB 1 +ATOM 25181 C CG . PHE N 1 56 ? 35.883 40.836 49.872 1.00 72.69 ? 56 PHE N CG 1 +ATOM 25182 C CD1 . PHE N 1 56 ? 35.027 40.228 48.968 1.00 43.95 ? 56 PHE N CD1 1 +ATOM 25183 C CD2 . PHE N 1 56 ? 37.055 41.366 49.412 1.00 90.72 ? 56 PHE N CD2 1 +ATOM 25184 C CE1 . PHE N 1 56 ? 35.367 40.097 47.655 1.00 35.27 ? 56 PHE N CE1 1 +ATOM 25185 C CE2 . PHE N 1 56 ? 37.422 41.183 48.092 1.00 72.33 ? 56 PHE N CE2 1 +ATOM 25186 C CZ . PHE N 1 56 ? 36.559 40.569 47.209 1.00 43.24 ? 56 PHE N CZ 1 +ATOM 25187 N N . SER N 1 57 ? 33.935 43.053 53.615 1.00 84.21 ? 57 SER N N 1 +ATOM 25188 C CA . SER N 1 57 ? 33.670 43.151 55.042 1.00 70.07 ? 57 SER N CA 1 +ATOM 25189 C C . SER N 1 57 ? 32.193 42.860 55.310 1.00 64.99 ? 57 SER N C 1 +ATOM 25190 O O . SER N 1 57 ? 31.296 43.607 54.859 1.00 79.40 ? 57 SER N O 1 +ATOM 25191 C CB . SER N 1 57 ? 34.075 44.532 55.571 1.00 69.35 ? 57 SER N CB 1 +ATOM 25192 O OG . SER N 1 57 ? 35.487 44.627 55.639 1.00 60.33 ? 57 SER N OG 1 +ATOM 25193 N N . THR N 1 58 ? 31.924 41.777 56.023 1.00 46.48 ? 58 THR N N 1 +ATOM 25194 C CA . THR N 1 58 ? 30.552 41.432 56.315 1.00 57.19 ? 58 THR N CA 1 +ATOM 25195 C C . THR N 1 58 ? 29.935 42.413 57.295 1.00 72.81 ? 58 THR N C 1 +ATOM 25196 O O . THR N 1 58 ? 30.584 42.940 58.166 1.00 77.05 ? 58 THR N O 1 +ATOM 25197 C CB . THR N 1 58 ? 30.451 40.030 56.918 1.00 44.99 ? 58 THR N CB 1 +ATOM 25198 O OG1 . THR N 1 58 ? 31.153 39.995 58.151 1.00 35.76 ? 58 THR N OG1 1 +ATOM 25199 C CG2 . THR N 1 58 ? 31.058 39.069 55.982 1.00 39.48 ? 58 THR N CG2 1 +ATOM 25200 N N . ALA N 1 59 ? 28.629 42.578 57.237 1.00 103.95 ? 59 ALA N N 1 +ATOM 25201 C CA . ALA N 1 59 ? 27.997 43.505 58.166 1.00 97.82 ? 59 ALA N CA 1 +ATOM 25202 C C . ALA N 1 59 ? 27.875 42.914 59.566 1.00 83.34 ? 59 ALA N C 1 +ATOM 25203 O O . ALA N 1 59 ? 27.747 43.641 60.540 1.00 95.28 ? 59 ALA N O 1 +ATOM 25204 C CB . ALA N 1 59 ? 26.636 43.917 57.656 1.00 116.75 ? 59 ALA N CB 1 +ATOM 25205 N N . VAL N 1 60 ? 27.935 41.588 59.658 1.00 93.45 ? 60 VAL N N 1 +ATOM 25206 C CA . VAL N 1 60 ? 27.687 40.874 60.901 1.00 92.81 ? 60 VAL N CA 1 +ATOM 25207 C C . VAL N 1 60 ? 28.798 39.863 61.114 1.00 82.84 ? 60 VAL N C 1 +ATOM 25208 O O . VAL N 1 60 ? 29.245 39.205 60.159 1.00 94.59 ? 60 VAL N O 1 +ATOM 25209 C CB . VAL N 1 60 ? 26.345 40.129 60.807 1.00 109.20 ? 60 VAL N CB 1 +ATOM 25210 C CG1 . VAL N 1 60 ? 26.054 39.337 62.082 1.00 129.54 ? 60 VAL N CG1 1 +ATOM 25211 C CG2 . VAL N 1 60 ? 25.221 41.109 60.514 1.00 111.23 ? 60 VAL N CG2 1 +ATOM 25212 N N . PRO N 1 61 ? 29.226 39.696 62.360 1.00 60.23 ? 61 PRO N N 1 +ATOM 25213 C CA . PRO N 1 61 ? 30.293 38.732 62.581 1.00 77.40 ? 61 PRO N CA 1 +ATOM 25214 C C . PRO N 1 61 ? 29.862 37.300 62.316 1.00 84.57 ? 61 PRO N C 1 +ATOM 25215 O O . PRO N 1 61 ? 28.712 36.937 62.592 1.00 53.24 ? 61 PRO N O 1 +ATOM 25216 C CB . PRO N 1 61 ? 30.634 38.909 64.061 1.00 76.78 ? 61 PRO N CB 1 +ATOM 25217 C CG . PRO N 1 61 ? 29.433 39.553 64.648 1.00 61.83 ? 61 PRO N CG 1 +ATOM 25218 C CD . PRO N 1 61 ? 28.901 40.438 63.567 1.00 53.91 ? 61 PRO N CD 1 +ATOM 25219 N N . GLN N 1 62 ? 30.805 36.495 61.806 1.00 105.27 ? 62 GLN N N 1 +ATOM 25220 C CA . GLN N 1 62 ? 30.523 35.124 61.397 1.00 98.36 ? 62 GLN N CA 1 +ATOM 25221 C C . GLN N 1 62 ? 30.722 34.189 62.577 1.00 98.13 ? 62 GLN N C 1 +ATOM 25222 O O . GLN N 1 62 ? 31.077 33.028 62.383 1.00 156.11 ? 62 GLN N O 1 +ATOM 25223 C CB . GLN N 1 62 ? 31.463 34.683 60.269 1.00 83.74 ? 62 GLN N CB 1 +ATOM 25224 C CG . GLN N 1 62 ? 31.560 35.658 59.125 1.00 72.95 ? 62 GLN N CG 1 +ATOM 25225 C CD . GLN N 1 62 ? 30.219 35.914 58.498 1.00 70.14 ? 62 GLN N CD 1 +ATOM 25226 O OE1 . GLN N 1 62 ? 29.694 35.077 57.737 1.00 113.62 ? 62 GLN N OE1 1 +ATOM 25227 N NE2 . GLN N 1 62 ? 29.646 37.070 58.786 1.00 53.88 ? 62 GLN N NE2 1 +ATOM 25228 N N . SER N 1 63 ? 30.381 34.654 63.772 1.00 68.34 ? 63 SER N N 1 +ATOM 25229 C CA . SER N 1 63 ? 30.760 33.962 64.971 1.00 64.46 ? 63 SER N CA 1 +ATOM 25230 C C . SER N 1 63 ? 29.568 33.483 65.818 1.00 72.96 ? 63 SER N C 1 +ATOM 25231 O O . SER N 1 63 ? 29.719 33.061 66.970 1.00 79.30 ? 63 SER N O 1 +ATOM 25232 C CB . SER N 1 63 ? 31.668 34.900 65.757 1.00 71.11 ? 63 SER N CB 1 +ATOM 25233 O OG . SER N 1 63 ? 31.019 36.093 66.163 1.00 90.12 ? 63 SER N OG 1 +ATOM 25234 N N . ALA N 1 64 ? 28.367 33.599 65.261 1.00 85.36 ? 64 ALA N N 1 +ATOM 25235 C CA . ALA N 1 64 ? 27.128 33.350 65.997 1.00 89.64 ? 64 ALA N CA 1 +ATOM 25236 C C . ALA N 1 64 ? 27.099 31.964 66.684 1.00 107.95 ? 64 ALA N C 1 +ATOM 25237 O O . ALA N 1 64 ? 26.585 31.809 67.801 1.00 75.96 ? 64 ALA N O 1 +ATOM 25238 C CB . ALA N 1 64 ? 25.950 33.501 65.054 1.00 88.72 ? 64 ALA N CB 1 +ATOM 25239 N N . THR N 1 65 ? 27.642 30.966 65.994 1.00 128.21 ? 65 THR N N 1 +ATOM 25240 C CA . THR N 1 65 ? 27.648 29.591 66.472 1.00 125.16 ? 65 THR N CA 1 +ATOM 25241 C C . THR N 1 65 ? 28.255 29.508 67.858 1.00 125.86 ? 65 THR N C 1 +ATOM 25242 O O . THR N 1 65 ? 27.688 28.884 68.763 1.00 191.71 ? 65 THR N O 1 +ATOM 25243 C CB . THR N 1 65 ? 28.495 28.724 65.540 1.00 118.16 ? 65 THR N CB 1 +ATOM 25244 O OG1 . THR N 1 65 ? 28.235 29.124 64.192 1.00 143.88 ? 65 THR N OG1 1 +ATOM 25245 C CG2 . THR N 1 65 ? 28.174 27.244 65.732 1.00 106.39 ? 65 THR N CG2 1 +ATOM 25246 N N . ALA N 1 66 ? 29.413 30.127 68.021 1.00 96.43 ? 66 ALA N N 1 +ATOM 25247 C CA . ALA N 1 66 ? 30.126 30.013 69.266 1.00 95.37 ? 66 ALA N CA 1 +ATOM 25248 C C . ALA N 1 66 ? 29.406 30.788 70.354 1.00 80.03 ? 66 ALA N C 1 +ATOM 25249 O O . ALA N 1 66 ? 29.428 30.391 71.539 1.00 59.60 ? 66 ALA N O 1 +ATOM 25250 C CB . ALA N 1 66 ? 31.553 30.501 69.083 1.00 125.72 ? 66 ALA N CB 1 +ATOM 25251 N N . MET N 1 67 ? 28.778 31.901 69.952 1.00 74.49 ? 67 MET N N 1 +ATOM 25252 C CA . MET N 1 67 ? 28.026 32.748 70.898 1.00 87.69 ? 67 MET N CA 1 +ATOM 25253 C C . MET N 1 67 ? 26.825 31.969 71.448 1.00 97.93 ? 67 MET N C 1 +ATOM 25254 O O . MET N 1 67 ? 26.543 31.983 72.660 1.00 80.25 ? 67 MET N O 1 +ATOM 25255 C CB . MET N 1 67 ? 27.533 34.032 70.241 1.00 66.73 ? 67 MET N CB 1 +ATOM 25256 C CG . MET N 1 67 ? 28.610 35.057 69.909 1.00 57.94 ? 67 MET N CG 1 +ATOM 25257 S SD . MET N 1 67 ? 27.926 36.351 68.833 1.00 96.37 ? 67 MET N SD 1 +ATOM 25258 C CE . MET N 1 67 ? 29.295 37.506 68.770 1.00 79.70 ? 67 MET N CE 1 +ATOM 25259 N N . LEU N 1 68 ? 26.187 31.205 70.566 1.00 98.50 ? 68 LEU N N 1 +ATOM 25260 C CA . LEU N 1 68 ? 25.051 30.382 70.979 1.00 94.22 ? 68 LEU N CA 1 +ATOM 25261 C C . LEU N 1 68 ? 25.484 29.280 71.932 1.00 84.26 ? 68 LEU N C 1 +ATOM 25262 O O . LEU N 1 68 ? 24.823 29.061 72.941 1.00 95.33 ? 68 LEU N O 1 +ATOM 25263 C CB . LEU N 1 68 ? 24.340 29.751 69.781 1.00 74.85 ? 68 LEU N CB 1 +ATOM 25264 C CG . LEU N 1 68 ? 23.294 28.710 70.199 1.00 60.67 ? 68 LEU N CG 1 +ATOM 25265 C CD1 . LEU N 1 68 ? 22.135 29.373 70.923 1.00 75.37 ? 68 LEU N CD1 1 +ATOM 25266 C CD2 . LEU N 1 68 ? 22.772 27.936 69.008 1.00 65.49 ? 68 LEU N CD2 1 +ATOM 25267 N N . VAL N 1 69 ? 26.586 28.601 71.611 1.00 79.62 ? 69 VAL N N 1 +ATOM 25268 C CA . VAL N 1 69 ? 27.086 27.528 72.461 1.00 87.38 ? 69 VAL N CA 1 +ATOM 25269 C C . VAL N 1 69 ? 27.438 28.082 73.840 1.00 102.58 ? 69 VAL N C 1 +ATOM 25270 O O . VAL N 1 69 ? 27.059 27.510 74.875 1.00 133.53 ? 69 VAL N O 1 +ATOM 25271 C CB . VAL N 1 69 ? 28.334 26.852 71.890 1.00 96.56 ? 69 VAL N CB 1 +ATOM 25272 C CG1 . VAL N 1 69 ? 28.898 25.879 72.913 1.00 128.52 ? 69 VAL N CG1 1 +ATOM 25273 C CG2 . VAL N 1 69 ? 28.036 26.109 70.600 1.00 84.27 ? 69 VAL N CG2 1 +ATOM 25274 N N . THR N 1 70 ? 28.095 29.234 73.851 1.00 101.65 ? 70 THR N N 1 +ATOM 25275 C CA . THR N 1 70 ? 28.420 29.907 75.100 1.00 115.09 ? 70 THR N CA 1 +ATOM 25276 C C . THR N 1 70 ? 27.177 30.306 75.903 1.00 113.21 ? 70 THR N C 1 +ATOM 25277 O O . THR N 1 70 ? 27.114 30.079 77.129 1.00 140.18 ? 70 THR N O 1 +ATOM 25278 C CB . THR N 1 70 ? 29.273 31.148 74.830 1.00 127.39 ? 70 THR N CB 1 +ATOM 25279 O OG1 . THR N 1 70 ? 30.410 30.750 74.052 1.00 135.66 ? 70 THR N OG1 1 +ATOM 25280 C CG2 . THR N 1 70 ? 29.738 31.800 76.152 1.00 131.32 ? 70 THR N CG2 1 +ATOM 25281 N N . ALA N 1 71 ? 26.191 30.898 75.227 1.00 100.24 ? 71 ALA N N 1 +ATOM 25282 C CA . ALA N 1 71 ? 24.929 31.244 75.889 1.00 109.95 ? 71 ALA N CA 1 +ATOM 25283 C C . ALA N 1 71 ? 24.186 30.010 76.449 1.00 102.75 ? 71 ALA N C 1 +ATOM 25284 O O . ALA N 1 71 ? 23.708 30.019 77.603 1.00 133.07 ? 71 ALA N O 1 +ATOM 25285 C CB . ALA N 1 71 ? 24.021 31.987 74.940 1.00 103.71 ? 71 ALA N CB 1 +ATOM 25286 N N . LEU N 1 72 ? 24.154 28.939 75.664 1.00 85.70 ? 72 LEU N N 1 +ATOM 25287 C CA . LEU N 1 72 ? 23.614 27.659 76.141 1.00 91.22 ? 72 LEU N CA 1 +ATOM 25288 C C . LEU N 1 72 ? 24.330 27.118 77.393 1.00 109.24 ? 72 LEU N C 1 +ATOM 25289 O O . LEU N 1 72 ? 23.735 26.400 78.195 1.00 89.08 ? 72 LEU N O 1 +ATOM 25290 C CB . LEU N 1 72 ? 23.676 26.589 75.049 1.00 75.09 ? 72 LEU N CB 1 +ATOM 25291 C CG . LEU N 1 72 ? 22.790 26.878 73.852 1.00 76.25 ? 72 LEU N CG 1 +ATOM 25292 C CD1 . LEU N 1 72 ? 23.237 26.017 72.708 1.00 85.89 ? 72 LEU N CD1 1 +ATOM 25293 C CD2 . LEU N 1 72 ? 21.334 26.611 74.153 1.00 102.48 ? 72 LEU N CD2 1 +ATOM 25294 N N . LYS N 1 73 ? 25.603 27.466 77.559 1.00 118.72 ? 73 LYS N N 1 +ATOM 25295 C CA . LYS N 1 73 ? 26.350 27.009 78.728 1.00 111.32 ? 73 LYS N CA 1 +ATOM 25296 C C . LYS N 1 73 ? 26.132 27.901 79.934 1.00 110.46 ? 73 LYS N C 1 +ATOM 25297 O O . LYS N 1 73 ? 25.904 27.409 81.033 1.00 103.29 ? 73 LYS N O 1 +ATOM 25298 C CB . LYS N 1 73 ? 27.835 26.961 78.433 1.00 116.94 ? 73 LYS N CB 1 +ATOM 25299 C CG . LYS N 1 73 ? 28.605 26.268 79.522 1.00 114.46 ? 73 LYS N CG 1 +ATOM 25300 C CD . LYS N 1 73 ? 30.007 26.798 79.554 1.00 134.51 ? 73 LYS N CD 1 +ATOM 25301 C CE . LYS N 1 73 ? 30.154 28.160 80.272 1.00 126.22 ? 73 LYS N CE 1 +ATOM 25302 N NZ . LYS N 1 73 ? 30.766 28.013 81.626 1.00 135.55 ? 73 LYS N NZ 1 +ATOM 25303 N N . ASP N 1 74 ? 26.201 29.216 79.717 1.00 108.97 ? 74 ASP N N 1 +ATOM 25304 C CA . ASP N 1 74 ? 26.036 30.192 80.793 1.00 112.19 ? 74 ASP N CA 1 +ATOM 25305 C C . ASP N 1 74 ? 24.672 30.067 81.485 1.00 124.58 ? 74 ASP N C 1 +ATOM 25306 O O . ASP N 1 74 ? 24.557 30.356 82.684 1.00 183.58 ? 74 ASP N O 1 +ATOM 25307 C CB . ASP N 1 74 ? 26.210 31.631 80.277 1.00 103.03 ? 74 ASP N CB 1 +ATOM 25308 C CG . ASP N 1 74 ? 27.645 31.944 79.851 1.00 112.79 ? 74 ASP N CG 1 +ATOM 25309 O OD1 . ASP N 1 74 ? 28.613 31.324 80.374 1.00 100.01 ? 74 ASP N OD1 1 +ATOM 25310 O OD2 . ASP N 1 74 ? 27.791 32.807 78.959 1.00 106.30 ? 74 ASP N OD2 1 +ATOM 25311 N N . SER N 1 75 ? 23.661 29.598 80.749 1.00 106.66 ? 75 SER N N 1 +ATOM 25312 C CA . SER N 1 75 ? 22.291 29.458 81.281 1.00 96.95 ? 75 SER N CA 1 +ATOM 25313 C C . SER N 1 75 ? 22.189 28.426 82.410 1.00 108.12 ? 75 SER N C 1 +ATOM 25314 O O . SER N 1 75 ? 21.288 28.505 83.241 1.00 108.82 ? 75 SER N O 1 +ATOM 25315 C CB . SER N 1 75 ? 21.321 29.063 80.171 1.00 85.02 ? 75 SER N CB 1 +ATOM 25316 O OG . SER N 1 75 ? 21.301 27.654 79.987 1.00 72.59 ? 75 SER N OG 1 +ATOM 25317 N N . ARG N 1 76 ? 23.133 27.484 82.440 1.00 129.42 ? 76 ARG N N 1 +ATOM 25318 C CA . ARG N 1 76 ? 23.176 26.413 83.449 1.00 131.44 ? 76 ARG N CA 1 +ATOM 25319 C C . ARG N 1 76 ? 21.927 25.524 83.269 1.00 117.28 ? 76 ARG N C 1 +ATOM 25320 O O . ARG N 1 76 ? 21.391 24.989 84.230 1.00 156.20 ? 76 ARG N O 1 +ATOM 25321 C CB . ARG N 1 76 ? 23.356 26.970 84.915 1.00 131.98 ? 76 ARG N CB 1 +ATOM 25322 C CG . ARG N 1 76 ? 23.112 25.933 85.975 1.00 156.54 ? 76 ARG N CG 1 +ATOM 25323 C CD . ARG N 1 76 ? 23.796 24.583 85.835 1.00 158.49 ? 76 ARG N CD 1 +ATOM 25324 N NE . ARG N 1 76 ? 25.193 24.560 86.372 1.00 159.70 ? 76 ARG N NE 1 +ATOM 25325 C CZ . ARG N 1 76 ? 26.270 24.616 85.579 1.00 145.97 ? 76 ARG N CZ 1 +ATOM 25326 N NH1 . ARG N 1 76 ? 26.136 24.714 84.249 1.00 143.84 ? 76 ARG N NH1 1 +ATOM 25327 N NH2 . ARG N 1 76 ? 27.492 24.633 86.110 1.00 109.86 ? 76 ARG N NH2 1 +ATOM 25328 N N . TRP N 1 77 ? 21.496 25.360 82.026 1.00 99.85 ? 77 TRP N N 1 +ATOM 25329 C CA . TRP N 1 77 ? 20.458 24.406 81.679 1.00 103.27 ? 77 TRP N CA 1 +ATOM 25330 C C . TRP N 1 77 ? 20.997 23.294 80.767 1.00 118.46 ? 77 TRP N C 1 +ATOM 25331 O O . TRP N 1 77 ? 20.542 22.146 80.823 1.00 99.21 ? 77 TRP N O 1 +ATOM 25332 C CB . TRP N 1 77 ? 19.321 25.144 80.966 1.00 118.16 ? 77 TRP N CB 1 +ATOM 25333 C CG . TRP N 1 77 ? 18.240 25.617 81.884 1.00 114.93 ? 77 TRP N CG 1 +ATOM 25334 C CD1 . TRP N 1 77 ? 18.274 26.702 82.691 1.00 94.46 ? 77 TRP N CD1 1 +ATOM 25335 C CD2 . TRP N 1 77 ? 16.930 25.050 82.021 1.00 123.13 ? 77 TRP N CD2 1 +ATOM 25336 N NE1 . TRP N 1 77 ? 17.083 26.836 83.346 1.00 99.60 ? 77 TRP N NE1 1 +ATOM 25337 C CE2 . TRP N 1 77 ? 16.248 25.819 82.966 1.00 112.22 ? 77 TRP N CE2 1 +ATOM 25338 C CE3 . TRP N 1 77 ? 16.275 23.953 81.438 1.00 140.61 ? 77 TRP N CE3 1 +ATOM 25339 C CZ2 . TRP N 1 77 ? 14.944 25.531 83.355 1.00 136.51 ? 77 TRP N CZ2 1 +ATOM 25340 C CZ3 . TRP N 1 77 ? 14.979 23.669 81.826 1.00 131.81 ? 77 TRP N CZ3 1 +ATOM 25341 C CH2 . TRP N 1 77 ? 14.327 24.453 82.776 1.00 127.97 ? 77 TRP N CH2 1 +ATOM 25342 N N . PHE N 1 78 ? 21.969 23.653 79.926 1.00 142.71 ? 78 PHE N N 1 +ATOM 25343 C CA . PHE N 1 78 ? 22.500 22.768 78.881 1.00 116.78 ? 78 PHE N CA 1 +ATOM 25344 C C . PHE N 1 78 ? 24.004 22.508 79.022 1.00 114.02 ? 78 PHE N C 1 +ATOM 25345 O O . PHE N 1 78 ? 24.767 23.417 79.385 1.00 104.69 ? 78 PHE N O 1 +ATOM 25346 C CB . PHE N 1 78 ? 22.282 23.402 77.520 1.00 99.37 ? 78 PHE N CB 1 +ATOM 25347 C CG . PHE N 1 78 ? 20.862 23.765 77.246 1.00 102.87 ? 78 PHE N CG 1 +ATOM 25348 C CD1 . PHE N 1 78 ? 19.926 22.786 76.935 1.00 123.01 ? 78 PHE N CD1 1 +ATOM 25349 C CD2 . PHE N 1 78 ? 20.465 25.081 77.262 1.00 94.60 ? 78 PHE N CD2 1 +ATOM 25350 C CE1 . PHE N 1 78 ? 18.620 23.122 76.638 1.00 132.70 ? 78 PHE N CE1 1 +ATOM 25351 C CE2 . PHE N 1 78 ? 19.162 25.428 76.951 1.00 113.00 ? 78 PHE N CE2 1 +ATOM 25352 C CZ . PHE N 1 78 ? 18.238 24.448 76.644 1.00 123.30 ? 78 PHE N CZ 1 +ATOM 25353 N N . ILE N 1 79 ? 24.411 21.274 78.721 1.00 100.40 ? 79 ILE N N 1 +ATOM 25354 C CA . ILE N 1 79 ? 25.807 20.931 78.463 1.00 96.27 ? 79 ILE N CA 1 +ATOM 25355 C C . ILE N 1 79 ? 25.983 20.913 76.943 1.00 112.14 ? 79 ILE N C 1 +ATOM 25356 O O . ILE N 1 79 ? 25.212 20.239 76.249 1.00 96.64 ? 79 ILE N O 1 +ATOM 25357 C CB . ILE N 1 79 ? 26.137 19.531 78.974 1.00 96.16 ? 79 ILE N CB 1 +ATOM 25358 C CG1 . ILE N 1 79 ? 25.665 19.353 80.408 1.00 111.86 ? 79 ILE N CG1 1 +ATOM 25359 C CG2 . ILE N 1 79 ? 27.629 19.266 78.884 1.00 94.02 ? 79 ILE N CG2 1 +ATOM 25360 C CD1 . ILE N 1 79 ? 25.436 17.904 80.802 1.00 131.92 ? 79 ILE N CD1 1 +ATOM 25361 N N . PRO N 1 80 ? 26.911 21.738 76.415 1.00 118.28 ? 80 PRO N N 1 +ATOM 25362 C CA . PRO N 1 80 ? 27.062 21.719 74.976 1.00 99.61 ? 80 PRO N CA 1 +ATOM 25363 C C . PRO N 1 80 ? 28.109 20.728 74.576 1.00 114.05 ? 80 PRO N C 1 +ATOM 25364 O O . PRO N 1 80 ? 29.138 20.609 75.251 1.00 123.61 ? 80 PRO N O 1 +ATOM 25365 C CB . PRO N 1 80 ? 27.529 23.122 74.648 1.00 89.57 ? 80 PRO N CB 1 +ATOM 25366 C CG . PRO N 1 80 ? 27.049 23.948 75.773 1.00 128.19 ? 80 PRO N CG 1 +ATOM 25367 C CD . PRO N 1 80 ? 27.271 23.057 76.962 1.00 138.58 ? 80 PRO N CD 1 +ATOM 25368 N N . LEU N 1 81 ? 27.770 19.908 73.590 1.00 104.65 ? 81 LEU N N 1 +ATOM 25369 C CA . LEU N 1 81 ? 28.693 18.944 73.066 1.00 88.17 ? 81 LEU N CA 1 +ATOM 25370 C C . LEU N 1 81 ? 29.362 19.579 71.878 1.00 92.80 ? 81 LEU N C 1 +ATOM 25371 O O . LEU N 1 81 ? 28.700 20.322 71.117 1.00 79.09 ? 81 LEU N O 1 +ATOM 25372 C CB . LEU N 1 81 ? 27.974 17.664 72.691 1.00 70.78 ? 81 LEU N CB 1 +ATOM 25373 C CG . LEU N 1 81 ? 27.230 17.082 73.878 1.00 77.68 ? 81 LEU N CG 1 +ATOM 25374 C CD1 . LEU N 1 81 ? 26.459 15.870 73.434 1.00 57.20 ? 81 LEU N CD1 1 +ATOM 25375 C CD2 . LEU N 1 81 ? 28.204 16.698 74.989 1.00 105.53 ? 81 LEU N CD2 1 +ATOM 25376 N N . GLU N 1 82 ? 30.686 19.341 71.786 1.00 84.71 ? 82 GLU N N 1 +ATOM 25377 C CA . GLU N 1 82 ? 31.544 19.953 70.764 1.00 67.96 ? 82 GLU N CA 1 +ATOM 25378 C C . GLU N 1 82 ? 31.394 19.277 69.387 1.00 65.83 ? 82 GLU N C 1 +ATOM 25379 O O . GLU N 1 82 ? 31.782 18.129 69.194 1.00 34.86 ? 82 GLU N O 1 +ATOM 25380 C CB . GLU N 1 82 ? 33.009 19.966 71.178 1.00 53.94 ? 82 GLU N CB 1 +ATOM 25381 C CG . GLU N 1 82 ? 33.918 20.602 70.150 1.00 70.85 ? 82 GLU N CG 1 +ATOM 25382 C CD . GLU N 1 82 ? 33.753 22.143 70.025 1.00 101.39 ? 82 GLU N CD 1 +ATOM 25383 O OE1 . GLU N 1 82 ? 32.617 22.684 69.825 1.00 95.64 ? 82 GLU N OE1 1 +ATOM 25384 O OE2 . GLU N 1 82 ? 34.807 22.833 69.941 1.00 153.27 ? 82 GLU N OE2 1 +ATOM 25385 N N . ARG N 1 83 ? 30.687 19.986 68.497 1.00 71.80 ? 83 ARG N N 1 +ATOM 25386 C CA . ARG N 1 83 ? 30.508 19.559 67.137 1.00 63.50 ? 83 ARG N CA 1 +ATOM 25387 C C . ARG N 1 83 ? 31.042 20.590 66.130 1.00 75.48 ? 83 ARG N C 1 +ATOM 25388 O O . ARG N 1 83 ? 31.346 20.228 64.990 1.00 85.45 ? 83 ARG N O 1 +ATOM 25389 C CB . ARG N 1 83 ? 29.028 19.274 66.857 1.00 64.61 ? 83 ARG N CB 1 +ATOM 25390 C CG . ARG N 1 83 ? 28.409 18.245 67.778 1.00 56.38 ? 83 ARG N CG 1 +ATOM 25391 C CD . ARG N 1 83 ? 28.959 16.851 67.542 1.00 51.31 ? 83 ARG N CD 1 +ATOM 25392 N NE . ARG N 1 83 ? 28.154 15.891 68.283 1.00 66.14 ? 83 ARG N NE 1 +ATOM 25393 C CZ . ARG N 1 83 ? 28.469 15.360 69.474 1.00 100.13 ? 83 ARG N CZ 1 +ATOM 25394 N NH1 . ARG N 1 83 ? 29.655 15.570 70.035 1.00 104.91 ? 83 ARG N NH1 1 +ATOM 25395 N NH2 . ARG N 1 83 ? 27.591 14.569 70.085 1.00 124.96 ? 83 ARG N NH2 1 +ATOM 25396 N N . GLN N 1 84 ? 31.168 21.861 66.507 1.00 77.66 ? 84 GLN N N 1 +ATOM 25397 C CA . GLN N 1 84 ? 31.750 22.819 65.558 1.00 86.49 ? 84 GLN N CA 1 +ATOM 25398 C C . GLN N 1 84 ? 33.133 22.338 65.081 1.00 87.68 ? 84 GLN N C 1 +ATOM 25399 O O . GLN N 1 84 ? 33.460 22.430 63.919 1.00 89.25 ? 84 GLN N O 1 +ATOM 25400 C CB . GLN N 1 84 ? 31.817 24.247 66.123 1.00 100.55 ? 84 GLN N CB 1 +ATOM 25401 C CG . GLN N 1 84 ? 31.647 25.350 65.070 1.00 99.39 ? 84 GLN N CG 1 +ATOM 25402 C CD . GLN N 1 84 ? 31.792 26.760 65.646 1.00 122.07 ? 84 GLN N CD 1 +ATOM 25403 O OE1 . GLN N 1 84 ? 31.425 27.016 66.787 1.00 122.61 ? 84 GLN N OE1 1 +ATOM 25404 N NE2 . GLN N 1 84 ? 32.394 27.661 64.873 1.00 133.27 ? 84 GLN N NE2 1 +ATOM 25405 N N . GLY N 1 85 ? 33.960 21.825 65.979 1.00 103.92 ? 85 GLY N N 1 +ATOM 25406 C CA . GLY N 1 85 ? 35.281 21.347 65.564 1.00 98.48 ? 85 GLY N CA 1 +ATOM 25407 C C . GLY N 1 85 ? 35.389 19.832 65.614 1.00 91.53 ? 85 GLY N C 1 +ATOM 25408 O O . GLY N 1 85 ? 36.421 19.297 66.028 1.00 51.98 ? 85 GLY N O 1 +ATOM 25409 N N . LEU N 1 86 ? 34.331 19.132 65.193 1.00 83.87 ? 86 LEU N N 1 +ATOM 25410 C CA . LEU N 1 86 ? 34.224 17.689 65.452 1.00 76.12 ? 86 LEU N CA 1 +ATOM 25411 C C . LEU N 1 86 ? 35.403 16.938 64.850 1.00 78.41 ? 86 LEU N C 1 +ATOM 25412 O O . LEU N 1 86 ? 35.864 15.933 65.390 1.00 67.56 ? 86 LEU N O 1 +ATOM 25413 C CB . LEU N 1 86 ? 32.898 17.135 64.908 1.00 66.03 ? 86 LEU N CB 1 +ATOM 25414 C CG . LEU N 1 86 ? 32.631 15.621 64.887 1.00 59.76 ? 86 LEU N CG 1 +ATOM 25415 C CD1 . LEU N 1 86 ? 32.696 15.005 66.272 1.00 69.93 ? 86 LEU N CD1 1 +ATOM 25416 C CD2 . LEU N 1 86 ? 31.277 15.319 64.277 1.00 55.72 ? 86 LEU N CD2 1 +ATOM 25417 N N . GLN N 1 87 ? 35.878 17.423 63.712 1.00 99.68 ? 87 GLN N N 1 +ATOM 25418 C CA . GLN N 1 87 ? 36.897 16.709 62.969 1.00 103.22 ? 87 GLN N CA 1 +ATOM 25419 C C . GLN N 1 87 ? 38.167 16.577 63.815 1.00 85.92 ? 87 GLN N C 1 +ATOM 25420 O O . GLN N 1 87 ? 38.821 15.508 63.849 1.00 95.26 ? 87 GLN N O 1 +ATOM 25421 C CB . GLN N 1 87 ? 37.151 17.407 61.619 1.00 103.79 ? 87 GLN N CB 1 +ATOM 25422 C CG . GLN N 1 87 ? 37.512 16.435 60.500 1.00 107.00 ? 87 GLN N CG 1 +ATOM 25423 C CD . GLN N 1 87 ? 36.663 15.152 60.532 1.00 95.36 ? 87 GLN N CD 1 +ATOM 25424 O OE1 . GLN N 1 87 ? 35.439 15.210 60.376 1.00 95.14 ? 87 GLN N OE1 1 +ATOM 25425 N NE2 . GLN N 1 87 ? 37.320 13.992 60.627 1.00 74.53 ? 87 GLN N NE2 1 +ATOM 25426 N N . ASN N 1 88 ? 38.523 17.661 64.490 1.00 69.40 ? 88 ASN N N 1 +ATOM 25427 C CA . ASN N 1 88 ? 39.748 17.677 65.304 1.00 97.23 ? 88 ASN N CA 1 +ATOM 25428 C C . ASN N 1 88 ? 39.622 16.745 66.495 1.00 86.85 ? 88 ASN N C 1 +ATOM 25429 O O . ASN N 1 88 ? 40.597 16.141 66.941 1.00 96.68 ? 88 ASN N O 1 +ATOM 25430 C CB . ASN N 1 88 ? 40.027 19.084 65.820 1.00 102.58 ? 88 ASN N CB 1 +ATOM 25431 C CG . ASN N 1 88 ? 40.160 20.088 64.711 1.00 106.75 ? 88 ASN N CG 1 +ATOM 25432 O OD1 . ASN N 1 88 ? 40.729 19.786 63.670 1.00 94.23 ? 88 ASN N OD1 1 +ATOM 25433 N ND2 . ASN N 1 88 ? 39.595 21.283 64.910 1.00 136.81 ? 88 ASN N ND2 1 +ATOM 25434 N N . LEU N 1 89 ? 38.406 16.655 67.003 1.00 69.26 ? 89 LEU N N 1 +ATOM 25435 C CA . LEU N 1 89 ? 38.139 15.860 68.169 1.00 60.66 ? 89 LEU N CA 1 +ATOM 25436 C C . LEU N 1 89 ? 38.354 14.414 67.794 1.00 77.91 ? 89 LEU N C 1 +ATOM 25437 O O . LEU N 1 89 ? 39.005 13.638 68.506 1.00 94.64 ? 89 LEU N O 1 +ATOM 25438 C CB . LEU N 1 89 ? 36.697 16.105 68.574 1.00 57.02 ? 89 LEU N CB 1 +ATOM 25439 C CG . LEU N 1 89 ? 36.318 15.945 70.034 1.00 46.95 ? 89 LEU N CG 1 +ATOM 25440 C CD1 . LEU N 1 89 ? 35.336 14.812 70.182 1.00 44.57 ? 89 LEU N CD1 1 +ATOM 25441 C CD2 . LEU N 1 89 ? 37.522 15.722 70.917 1.00 43.72 ? 89 LEU N CD2 1 +ATOM 25442 N N . LEU N 1 90 ? 37.885 14.058 66.601 1.00 97.95 ? 90 LEU N N 1 +ATOM 25443 C CA . LEU N 1 90 ? 38.018 12.670 66.110 1.00 98.26 ? 90 LEU N CA 1 +ATOM 25444 C C . LEU N 1 90 ? 39.483 12.321 65.790 1.00 93.24 ? 90 LEU N C 1 +ATOM 25445 O O . LEU N 1 90 ? 39.921 11.171 65.938 1.00 63.47 ? 90 LEU N O 1 +ATOM 25446 C CB . LEU N 1 90 ? 37.147 12.457 64.869 1.00 71.63 ? 90 LEU N CB 1 +ATOM 25447 C CG . LEU N 1 90 ? 35.667 12.697 65.086 1.00 50.37 ? 90 LEU N CG 1 +ATOM 25448 C CD1 . LEU N 1 90 ? 34.995 12.909 63.751 1.00 40.65 ? 90 LEU N CD1 1 +ATOM 25449 C CD2 . LEU N 1 90 ? 35.078 11.519 65.838 1.00 61.01 ? 90 LEU N CD2 1 +ATOM 25450 N N . ASN N 1 91 ? 40.229 13.343 65.379 1.00 81.71 ? 91 ASN N N 1 +ATOM 25451 C CA . ASN N 1 91 ? 41.628 13.182 65.103 1.00 87.53 ? 91 ASN N CA 1 +ATOM 25452 C C . ASN N 1 91 ? 42.407 12.878 66.380 1.00 97.63 ? 91 ASN N C 1 +ATOM 25453 O O . ASN N 1 91 ? 43.253 11.974 66.405 1.00 94.93 ? 91 ASN N O 1 +ATOM 25454 C CB . ASN N 1 91 ? 42.174 14.429 64.397 1.00 78.65 ? 91 ASN N CB 1 +ATOM 25455 C CG . ASN N 1 91 ? 42.880 14.072 63.123 1.00 103.14 ? 91 ASN N CG 1 +ATOM 25456 O OD1 . ASN N 1 91 ? 42.329 13.279 62.324 1.00 125.58 ? 91 ASN N OD1 1 +ATOM 25457 N ND2 . ASN N 1 91 ? 44.173 14.430 63.028 1.00 105.87 ? 91 ASN N ND2 1 +ATOM 25458 N N . GLU N 1 92 ? 42.195 13.688 67.412 1.00 108.17 ? 92 GLU N N 1 +ATOM 25459 C CA . GLU N 1 92 ? 42.913 13.484 68.673 1.00 93.07 ? 92 GLU N CA 1 +ATOM 25460 C C . GLU N 1 92 ? 42.619 12.082 69.184 1.00 89.95 ? 92 GLU N C 1 +ATOM 25461 O O . GLU N 1 92 ? 43.458 11.438 69.807 1.00 56.48 ? 92 GLU N O 1 +ATOM 25462 C CB . GLU N 1 92 ? 42.520 14.555 69.699 1.00 82.21 ? 92 GLU N CB 1 +ATOM 25463 C CG . GLU N 1 92 ? 43.456 15.749 69.744 1.00 83.81 ? 92 GLU N CG 1 +ATOM 25464 C CD . GLU N 1 92 ? 44.935 15.355 69.922 1.00 95.92 ? 92 GLU N CD 1 +ATOM 25465 O OE1 . GLU N 1 92 ? 45.320 14.700 70.927 1.00 73.07 ? 92 GLU N OE1 1 +ATOM 25466 O OE2 . GLU N 1 92 ? 45.753 15.789 69.085 1.00 122.44 ? 92 GLU N OE2 1 +ATOM 25467 N N . ARG N 1 93 ? 41.388 11.640 68.957 1.00 90.60 ? 93 ARG N N 1 +ATOM 25468 C CA . ARG N 1 93 ? 40.985 10.332 69.420 1.00 94.85 ? 93 ARG N CA 1 +ATOM 25469 C C . ARG N 1 93 ? 41.698 9.246 68.617 1.00 95.41 ? 93 ARG N C 1 +ATOM 25470 O O . ARG N 1 93 ? 42.035 8.189 69.152 1.00 74.27 ? 93 ARG N O 1 +ATOM 25471 C CB . ARG N 1 93 ? 39.451 10.217 69.389 1.00 90.39 ? 93 ARG N CB 1 +ATOM 25472 C CG . ARG N 1 93 ? 38.811 11.090 70.471 1.00 94.61 ? 93 ARG N CG 1 +ATOM 25473 C CD . ARG N 1 93 ? 37.322 11.290 70.298 1.00 104.90 ? 93 ARG N CD 1 +ATOM 25474 N NE . ARG N 1 93 ? 36.553 10.427 71.184 1.00 80.12 ? 93 ARG N NE 1 +ATOM 25475 C CZ . ARG N 1 93 ? 36.057 9.240 70.842 1.00 65.98 ? 93 ARG N CZ 1 +ATOM 25476 N NH1 . ARG N 1 93 ? 36.242 8.716 69.631 1.00 61.27 ? 93 ARG N NH1 1 +ATOM 25477 N NH2 . ARG N 1 93 ? 35.314 8.609 71.723 1.00 67.79 ? 93 ARG N NH2 1 +ATOM 25478 N N . LYS N 1 94 ? 41.964 9.515 67.341 1.00 101.40 ? 94 LYS N N 1 +ATOM 25479 C CA . LYS N 1 94 ? 42.748 8.576 66.524 1.00 84.40 ? 94 LYS N CA 1 +ATOM 25480 C C . LYS N 1 94 ? 44.155 8.475 67.084 1.00 77.48 ? 94 LYS N C 1 +ATOM 25481 O O . LYS N 1 94 ? 44.714 7.370 67.163 1.00 65.60 ? 94 LYS N O 1 +ATOM 25482 C CB . LYS N 1 94 ? 42.840 9.049 65.076 1.00 79.23 ? 94 LYS N CB 1 +ATOM 25483 C CG . LYS N 1 94 ? 41.726 8.584 64.152 1.00 77.34 ? 94 LYS N CG 1 +ATOM 25484 C CD . LYS N 1 94 ? 41.840 9.288 62.810 1.00 83.90 ? 94 LYS N CD 1 +ATOM 25485 C CE . LYS N 1 94 ? 41.108 8.555 61.695 1.00 87.12 ? 94 LYS N CE 1 +ATOM 25486 N NZ . LYS N 1 94 ? 40.960 9.448 60.511 1.00 95.27 ? 94 LYS N NZ 1 +ATOM 25487 N N . ILE N 1 95 ? 44.705 9.622 67.505 1.00 65.49 ? 95 ILE N N 1 +ATOM 25488 C CA . ILE N 1 95 ? 46.090 9.649 67.959 1.00 58.91 ? 95 ILE N CA 1 +ATOM 25489 C C . ILE N 1 95 ? 46.203 8.945 69.278 1.00 65.66 ? 95 ILE N C 1 +ATOM 25490 O O . ILE N 1 95 ? 47.228 8.239 69.535 1.00 48.17 ? 95 ILE N O 1 +ATOM 25491 C CB . ILE N 1 95 ? 46.660 11.055 68.136 1.00 53.81 ? 95 ILE N CB 1 +ATOM 25492 C CG1 . ILE N 1 95 ? 46.385 11.915 66.906 1.00 70.51 ? 95 ILE N CG1 1 +ATOM 25493 C CG2 . ILE N 1 95 ? 48.171 10.924 68.300 1.00 49.58 ? 95 ILE N CG2 1 +ATOM 25494 C CD1 . ILE N 1 95 ? 47.187 13.218 66.806 1.00 58.57 ? 95 ILE N CD1 1 +ATOM 25495 N N . ILE N 1 96 ? 45.168 9.170 70.126 1.00 51.93 ? 96 ILE N N 1 +ATOM 25496 C CA . ILE N 1 96 ? 45.064 8.486 71.412 1.00 40.98 ? 96 ILE N CA 1 +ATOM 25497 C C . ILE N 1 96 ? 45.070 6.991 71.210 1.00 38.13 ? 96 ILE N C 1 +ATOM 25498 O O . ILE N 1 96 ? 45.954 6.288 71.700 1.00 33.63 ? 96 ILE N O 1 +ATOM 25499 C CB . ILE N 1 96 ? 43.817 8.872 72.166 1.00 37.87 ? 96 ILE N CB 1 +ATOM 25500 C CG1 . ILE N 1 96 ? 43.887 10.323 72.633 1.00 44.03 ? 96 ILE N CG1 1 +ATOM 25501 C CG2 . ILE N 1 96 ? 43.714 7.997 73.411 1.00 45.80 ? 96 ILE N CG2 1 +ATOM 25502 C CD1 . ILE N 1 96 ? 42.702 10.776 73.477 1.00 43.26 ? 96 ILE N CD1 1 +ATOM 25503 N N . ARG N 1 97 ? 44.129 6.519 70.418 1.00 43.51 ? 97 ARG N N 1 +ATOM 25504 C CA . ARG N 1 97 ? 43.976 5.084 70.209 1.00 60.15 ? 97 ARG N CA 1 +ATOM 25505 C C . ARG N 1 97 ? 45.230 4.483 69.596 1.00 67.87 ? 97 ARG N C 1 +ATOM 25506 O O . ARG N 1 97 ? 45.538 3.304 69.822 1.00 93.43 ? 97 ARG N O 1 +ATOM 25507 C CB . ARG N 1 97 ? 42.750 4.782 69.325 1.00 84.49 ? 97 ARG N CB 1 +ATOM 25508 C CG . ARG N 1 97 ? 41.515 4.272 70.080 1.00 78.53 ? 97 ARG N CG 1 +ATOM 25509 C CD . ARG N 1 97 ? 40.384 3.941 69.122 1.00 75.86 ? 97 ARG N CD 1 +ATOM 25510 N NE . ARG N 1 97 ? 39.649 5.129 68.709 1.00 78.61 ? 97 ARG N NE 1 +ATOM 25511 C CZ . ARG N 1 97 ? 38.496 5.525 69.237 1.00 97.51 ? 97 ARG N CZ 1 +ATOM 25512 N NH1 . ARG N 1 97 ? 37.930 4.838 70.221 1.00 83.25 ? 97 ARG N NH1 1 +ATOM 25513 N NH2 . ARG N 1 97 ? 37.912 6.633 68.778 1.00 118.67 ? 97 ARG N NH2 1 +ATOM 25514 N N . ALA N 1 98 ? 45.936 5.263 68.782 1.00 70.88 ? 98 ALA N N 1 +ATOM 25515 C CA . ALA N 1 98 ? 47.148 4.769 68.151 1.00 79.20 ? 98 ALA N CA 1 +ATOM 25516 C C . ALA N 1 98 ? 48.281 4.715 69.175 1.00 85.04 ? 98 ALA N C 1 +ATOM 25517 O O . ALA N 1 98 ? 49.200 3.886 69.050 1.00 73.29 ? 98 ALA N O 1 +ATOM 25518 C CB . ALA N 1 98 ? 47.516 5.653 66.980 1.00 92.10 ? 98 ALA N CB 1 +ATOM 25519 N N . ALA N 1 99 ? 48.202 5.593 70.189 1.00 85.68 ? 99 ALA N N 1 +ATOM 25520 C CA . ALA N 1 99 ? 49.222 5.686 71.270 1.00 76.70 ? 99 ALA N CA 1 +ATOM 25521 C C . ALA N 1 99 ? 49.205 4.526 72.219 1.00 85.31 ? 99 ALA N C 1 +ATOM 25522 O O . ALA N 1 99 ? 50.211 3.833 72.406 1.00 137.18 ? 99 ALA N O 1 +ATOM 25523 C CB . ALA N 1 99 ? 49.013 6.925 72.072 1.00 78.03 ? 99 ALA N CB 1 +ATOM 25524 N N . GLN N 1 100 ? 48.007 4.190 72.682 1.00 105.31 ? 100 GLN N N 1 +ATOM 25525 C CA . GLN N 1 100 ? 47.863 3.226 73.777 1.00 106.23 ? 100 GLN N CA 1 +ATOM 25526 C C . GLN N 1 100 ? 47.351 1.825 73.389 1.00 99.24 ? 100 GLN N C 1 +ATOM 25527 O O . GLN N 1 100 ? 47.115 0.985 74.263 1.00 110.27 ? 100 GLN N O 1 +ATOM 25528 C CB . GLN N 1 100 ? 46.972 3.818 74.865 1.00 88.59 ? 100 GLN N CB 1 +ATOM 25529 C CG . GLN N 1 100 ? 45.717 4.496 74.354 1.00 72.42 ? 100 GLN N CG 1 +ATOM 25530 C CD . GLN N 1 100 ? 45.230 5.593 75.265 1.00 62.21 ? 100 GLN N CD 1 +ATOM 25531 O OE1 . GLN N 1 100 ? 45.937 6.588 75.548 1.00 54.64 ? 100 GLN N OE1 1 +ATOM 25532 N NE2 . GLN N 1 100 ? 43.997 5.435 75.724 1.00 56.73 ? 100 GLN N NE2 1 +ATOM 25533 N N . GLU N 1 101 ? 47.237 1.553 72.089 1.00 90.66 ? 101 GLU N N 1 +ATOM 25534 C CA . GLU N 1 101 ? 46.731 0.258 71.625 1.00 92.29 ? 101 GLU N CA 1 +ATOM 25535 C C . GLU N 1 101 ? 47.678 -0.899 71.935 1.00 98.30 ? 101 GLU N C 1 +ATOM 25536 O O . GLU N 1 101 ? 47.249 -2.051 72.027 1.00 78.05 ? 101 GLU N O 1 +ATOM 25537 C CB . GLU N 1 101 ? 46.421 0.294 70.129 1.00 101.84 ? 101 GLU N CB 1 +ATOM 25538 C CG . GLU N 1 101 ? 47.562 0.791 69.250 1.00 108.36 ? 101 GLU N CG 1 +ATOM 25539 C CD . GLU N 1 101 ? 47.223 0.729 67.766 1.00 112.00 ? 101 GLU N CD 1 +ATOM 25540 O OE1 . GLU N 1 101 ? 46.021 0.634 67.433 1.00 111.04 ? 101 GLU N OE1 1 +ATOM 25541 O OE2 . GLU N 1 101 ? 48.153 0.791 66.931 1.00 107.60 ? 101 GLU N OE2 1 +ATOM 25542 N N . ASN N 1 102 ? 48.961 -0.601 72.117 1.00 113.25 ? 102 ASN N N 1 +ATOM 25543 C CA . ASN N 1 102 ? 49.944 -1.649 72.367 1.00 107.64 ? 102 ASN N CA 1 +ATOM 25544 C C . ASN N 1 102 ? 50.200 -1.907 73.834 1.00 97.97 ? 102 ASN N C 1 +ATOM 25545 O O . ASN N 1 102 ? 50.976 -2.799 74.181 1.00 108.90 ? 102 ASN N O 1 +ATOM 25546 C CB . ASN N 1 102 ? 51.252 -1.302 71.683 1.00 113.33 ? 102 ASN N CB 1 +ATOM 25547 C CG . ASN N 1 102 ? 51.148 -1.424 70.182 1.00 121.77 ? 102 ASN N CG 1 +ATOM 25548 O OD1 . ASN N 1 102 ? 51.219 -2.533 69.620 1.00 94.04 ? 102 ASN N OD1 1 +ATOM 25549 N ND2 . ASN N 1 102 ? 50.961 -0.287 69.517 1.00 130.78 ? 102 ASN N ND2 1 +ATOM 25550 N N . GLY N 1 103 ? 49.562 -1.131 74.701 1.00 90.61 ? 103 GLY N N 1 +ATOM 25551 C CA . GLY N 1 103 ? 49.735 -1.315 76.135 1.00 100.50 ? 103 GLY N CA 1 +ATOM 25552 C C . GLY N 1 103 ? 51.170 -1.132 76.596 1.00 102.29 ? 103 GLY N C 1 +ATOM 25553 O O . GLY N 1 103 ? 51.636 -1.791 77.542 1.00 115.37 ? 103 GLY N O 1 +ATOM 25554 N N . THR N 1 104 ? 51.880 -0.229 75.938 1.00 87.81 ? 104 THR N N 1 +ATOM 25555 C CA . THR N 1 104 ? 53.156 0.213 76.449 1.00 82.25 ? 104 THR N CA 1 +ATOM 25556 C C . THR N 1 104 ? 52.977 1.543 77.183 1.00 71.85 ? 104 THR N C 1 +ATOM 25557 O O . THR N 1 104 ? 53.748 1.855 78.074 1.00 83.72 ? 104 THR N O 1 +ATOM 25558 C CB . THR N 1 104 ? 54.230 0.317 75.334 1.00 74.88 ? 104 THR N CB 1 +ATOM 25559 O OG1 . THR N 1 104 ? 53.868 1.336 74.392 1.00 63.56 ? 104 THR N OG1 1 +ATOM 25560 C CG2 . THR N 1 104 ? 54.395 -1.019 74.629 1.00 68.63 ? 104 THR N CG2 1 +ATOM 25561 N N . VAL N 1 105 ? 51.960 2.315 76.826 1.00 75.42 ? 105 VAL N N 1 +ATOM 25562 C CA . VAL N 1 105 ? 51.867 3.706 77.310 1.00 116.07 ? 105 VAL N CA 1 +ATOM 25563 C C . VAL N 1 105 ? 51.735 3.709 78.823 1.00 130.90 ? 105 VAL N C 1 +ATOM 25564 O O . VAL N 1 105 ? 51.051 2.849 79.398 1.00 135.56 ? 105 VAL N O 1 +ATOM 25565 C CB . VAL N 1 105 ? 50.721 4.531 76.622 1.00 146.91 ? 105 VAL N CB 1 +ATOM 25566 C CG1 . VAL N 1 105 ? 50.069 5.517 77.589 1.00 127.26 ? 105 VAL N CG1 1 +ATOM 25567 C CG2 . VAL N 1 105 ? 51.247 5.282 75.381 1.00 139.23 ? 105 VAL N CG2 1 +ATOM 25568 N N . ALA N 1 106 ? 52.416 4.674 79.442 1.00 150.49 ? 106 ALA N N 1 +ATOM 25569 C CA . ALA N 1 106 ? 52.548 4.758 80.890 1.00 156.88 ? 106 ALA N CA 1 +ATOM 25570 C C . ALA N 1 106 ? 51.186 4.933 81.557 1.00 166.90 ? 106 ALA N C 1 +ATOM 25571 O O . ALA N 1 106 ? 50.369 5.749 81.124 1.00 179.10 ? 106 ALA N O 1 +ATOM 25572 C CB . ALA N 1 106 ? 53.472 5.909 81.260 1.00 139.35 ? 106 ALA N CB 1 +ATOM 25573 N N . ILE N 1 107 ? 50.954 4.160 82.613 1.00 151.35 ? 107 ILE N N 1 +ATOM 25574 C CA . ILE N 1 107 ? 49.644 4.099 83.268 1.00 135.97 ? 107 ILE N CA 1 +ATOM 25575 C C . ILE N 1 107 ? 49.173 5.474 83.792 1.00 122.60 ? 107 ILE N C 1 +ATOM 25576 O O . ILE N 1 107 ? 47.974 5.759 83.843 1.00 99.44 ? 107 ILE N O 1 +ATOM 25577 C CB . ILE N 1 107 ? 49.664 3.049 84.413 1.00 117.19 ? 107 ILE N CB 1 +ATOM 25578 C CG1 . ILE N 1 107 ? 48.245 2.744 84.910 1.00 104.14 ? 107 ILE N CG1 1 +ATOM 25579 C CG2 . ILE N 1 107 ? 50.552 3.518 85.562 1.00 120.66 ? 107 ILE N CG2 1 +ATOM 25580 C CD1 . ILE N 1 107 ? 47.287 2.249 83.845 1.00 94.39 ? 107 ILE N CD1 1 +ATOM 25581 N N . ASN N 1 108 ? 50.125 6.320 84.172 1.00 125.10 ? 108 ASN N N 1 +ATOM 25582 C CA . ASN N 1 108 ? 49.832 7.695 84.594 1.00 143.43 ? 108 ASN N CA 1 +ATOM 25583 C C . ASN N 1 108 ? 49.393 8.552 83.412 1.00 147.33 ? 108 ASN N C 1 +ATOM 25584 O O . ASN N 1 108 ? 48.559 9.446 83.547 1.00 141.80 ? 108 ASN N O 1 +ATOM 25585 C CB . ASN N 1 108 ? 51.070 8.337 85.228 1.00 158.63 ? 108 ASN N CB 1 +ATOM 25586 C CG . ASN N 1 108 ? 51.961 7.323 85.925 1.00 178.76 ? 108 ASN N CG 1 +ATOM 25587 O OD1 . ASN N 1 108 ? 51.761 7.011 87.097 1.00 197.22 ? 108 ASN N OD1 1 +ATOM 25588 N ND2 . ASN N 1 108 ? 52.954 6.805 85.203 1.00 178.57 ? 108 ASN N ND2 1 +ATOM 25589 N N . ASN N 1 109 ? 49.985 8.275 82.258 1.00 137.06 ? 109 ASN N N 1 +ATOM 25590 C CA . ASN N 1 109 ? 49.770 9.069 81.058 1.00 141.22 ? 109 ASN N CA 1 +ATOM 25591 C C . ASN N 1 109 ? 48.548 8.626 80.252 1.00 132.94 ? 109 ASN N C 1 +ATOM 25592 O O . ASN N 1 109 ? 48.054 9.372 79.398 1.00 115.05 ? 109 ASN N O 1 +ATOM 25593 C CB . ASN N 1 109 ? 51.020 9.007 80.178 1.00 145.17 ? 109 ASN N CB 1 +ATOM 25594 C CG . ASN N 1 109 ? 51.683 10.358 80.018 1.00 156.50 ? 109 ASN N CG 1 +ATOM 25595 O OD1 . ASN N 1 109 ? 51.707 10.922 78.920 1.00 124.12 ? 109 ASN N OD1 1 +ATOM 25596 N ND2 . ASN N 1 109 ? 52.193 10.906 81.120 1.00 159.05 ? 109 ASN N ND2 1 +ATOM 25597 N N . ARG N 1 110 ? 48.069 7.414 80.538 1.00 128.52 ? 110 ARG N N 1 +ATOM 25598 C CA . ARG N 1 110 ? 46.993 6.762 79.769 1.00 104.55 ? 110 ARG N CA 1 +ATOM 25599 C C . ARG N 1 110 ? 45.725 7.626 79.724 1.00 94.90 ? 110 ARG N C 1 +ATOM 25600 O O . ARG N 1 110 ? 45.308 8.184 80.740 1.00 112.78 ? 110 ARG N O 1 +ATOM 25601 C CB . ARG N 1 110 ? 46.663 5.411 80.417 1.00 89.76 ? 110 ARG N CB 1 +ATOM 25602 C CG . ARG N 1 110 ? 46.007 4.411 79.497 1.00 98.18 ? 110 ARG N CG 1 +ATOM 25603 C CD . ARG N 1 110 ? 46.426 2.988 79.832 1.00 104.68 ? 110 ARG N CD 1 +ATOM 25604 N NE . ARG N 1 110 ? 45.543 2.373 80.830 1.00 118.36 ? 110 ARG N NE 1 +ATOM 25605 C CZ . ARG N 1 110 ? 44.800 1.277 80.632 1.00 136.93 ? 110 ARG N CZ 1 +ATOM 25606 N NH1 . ARG N 1 110 ? 44.813 0.624 79.464 1.00 141.68 ? 110 ARG N NH1 1 +ATOM 25607 N NH2 . ARG N 1 110 ? 44.045 0.810 81.626 1.00 136.33 ? 110 ARG N NH2 1 +ATOM 25608 N N . ILE N 1 111 ? 45.117 7.751 78.550 1.00 83.69 ? 111 ILE N N 1 +ATOM 25609 C CA . ILE N 1 111 ? 43.845 8.470 78.429 1.00 82.53 ? 111 ILE N CA 1 +ATOM 25610 C C . ILE N 1 111 ? 42.726 7.498 78.139 1.00 94.13 ? 111 ILE N C 1 +ATOM 25611 O O . ILE N 1 111 ? 42.731 6.866 77.085 1.00 108.17 ? 111 ILE N O 1 +ATOM 25612 C CB . ILE N 1 111 ? 43.867 9.517 77.303 1.00 78.25 ? 111 ILE N CB 1 +ATOM 25613 C CG1 . ILE N 1 111 ? 44.893 10.602 77.637 1.00 94.90 ? 111 ILE N CG1 1 +ATOM 25614 C CG2 . ILE N 1 111 ? 42.483 10.127 77.122 1.00 71.80 ? 111 ILE N CG2 1 +ATOM 25615 C CD1 . ILE N 1 111 ? 45.221 11.536 76.485 1.00 110.97 ? 111 ILE N CD1 1 +ATOM 25616 N N . PRO N 1 112 ? 41.757 7.383 79.060 1.00 105.08 ? 112 PRO N N 1 +ATOM 25617 C CA . PRO N 1 112 ? 40.670 6.438 78.859 1.00 103.99 ? 112 PRO N CA 1 +ATOM 25618 C C . PRO N 1 112 ? 39.627 7.014 77.893 1.00 97.31 ? 112 PRO N C 1 +ATOM 25619 O O . PRO N 1 112 ? 39.157 8.144 78.076 1.00 64.29 ? 112 PRO N O 1 +ATOM 25620 C CB . PRO N 1 112 ? 40.104 6.271 80.268 1.00 98.06 ? 112 PRO N CB 1 +ATOM 25621 C CG . PRO N 1 112 ? 40.329 7.609 80.907 1.00 96.29 ? 112 PRO N CG 1 +ATOM 25622 C CD . PRO N 1 112 ? 41.545 8.217 80.259 1.00 96.39 ? 112 PRO N CD 1 +ATOM 25623 N N . LEU N 1 113 ? 39.261 6.217 76.898 1.00 107.05 ? 113 LEU N N 1 +ATOM 25624 C CA . LEU N 1 113 ? 38.373 6.664 75.843 1.00 115.75 ? 113 LEU N CA 1 +ATOM 25625 C C . LEU N 1 113 ? 36.986 6.047 75.935 1.00 89.42 ? 113 LEU N C 1 +ATOM 25626 O O . LEU N 1 113 ? 36.802 4.835 76.133 1.00 71.80 ? 113 LEU N O 1 +ATOM 25627 C CB . LEU N 1 113 ? 38.977 6.366 74.467 1.00 145.04 ? 113 LEU N CB 1 +ATOM 25628 C CG . LEU N 1 113 ? 39.927 7.427 73.928 1.00 137.25 ? 113 LEU N CG 1 +ATOM 25629 C CD1 . LEU N 1 113 ? 40.338 7.002 72.529 1.00 132.90 ? 113 LEU N CD1 1 +ATOM 25630 C CD2 . LEU N 1 113 ? 39.304 8.821 73.907 1.00 120.98 ? 113 LEU N CD2 1 +ATOM 25631 N N . GLN N 1 114 ? 36.020 6.896 75.657 1.00 82.75 ? 114 GLN N N 1 +ATOM 25632 C CA . GLN N 1 114 ? 34.639 6.589 75.880 1.00 104.72 ? 114 GLN N CA 1 +ATOM 25633 C C . GLN N 1 114 ? 33.903 7.141 74.699 1.00 98.14 ? 114 GLN N C 1 +ATOM 25634 O O . GLN N 1 114 ? 34.379 8.093 74.078 1.00 145.11 ? 114 GLN N O 1 +ATOM 25635 C CB . GLN N 1 114 ? 34.186 7.292 77.145 1.00 108.55 ? 114 GLN N CB 1 +ATOM 25636 C CG . GLN N 1 114 ? 33.067 6.593 77.868 1.00 115.25 ? 114 GLN N CG 1 +ATOM 25637 C CD . GLN N 1 114 ? 32.200 7.588 78.562 1.00 111.15 ? 114 GLN N CD 1 +ATOM 25638 O OE1 . GLN N 1 114 ? 32.698 8.617 79.047 1.00 132.15 ? 114 GLN N OE1 1 +ATOM 25639 N NE2 . GLN N 1 114 ? 30.893 7.296 78.639 1.00 107.04 ? 114 GLN N NE2 1 +ATOM 25640 N N . SER N 1 115 ? 32.818 6.483 74.319 1.00 97.79 ? 115 SER N N 1 +ATOM 25641 C CA . SER N 1 115 ? 32.094 6.838 73.101 1.00 119.86 ? 115 SER N CA 1 +ATOM 25642 C C . SER N 1 115 ? 31.662 8.275 73.196 1.00 105.85 ? 115 SER N C 1 +ATOM 25643 O O . SER N 1 115 ? 31.568 8.837 74.305 1.00 99.46 ? 115 SER N O 1 +ATOM 25644 C CB . SER N 1 115 ? 30.862 5.944 72.917 1.00 135.19 ? 115 SER N CB 1 +ATOM 25645 O OG . SER N 1 115 ? 30.076 5.897 74.102 1.00 115.25 ? 115 SER N OG 1 +ATOM 25646 N N . LEU N 1 116 ? 31.434 8.909 72.054 1.00 97.79 ? 116 LEU N N 1 +ATOM 25647 C CA . LEU N 1 116 ? 31.287 10.365 72.100 1.00 147.77 ? 116 LEU N CA 1 +ATOM 25648 C C . LEU N 1 116 ? 29.911 10.644 72.665 1.00 140.00 ? 116 LEU N C 1 +ATOM 25649 O O . LEU N 1 116 ? 28.951 10.043 72.207 1.00 105.98 ? 116 LEU N O 1 +ATOM 25650 C CB . LEU N 1 116 ? 31.421 11.008 70.719 1.00 159.22 ? 116 LEU N CB 1 +ATOM 25651 C CG . LEU N 1 116 ? 32.802 10.965 70.056 1.00 120.82 ? 116 LEU N CG 1 +ATOM 25652 C CD1 . LEU N 1 116 ? 32.921 9.753 69.120 1.00 120.66 ? 116 LEU N CD1 1 +ATOM 25653 C CD2 . LEU N 1 116 ? 33.025 12.264 69.317 1.00 82.20 ? 116 LEU N CD2 1 +ATOM 25654 N N . THR N 1 117 ? 29.848 11.449 73.726 1.00 138.39 ? 117 THR N N 1 +ATOM 25655 C CA . THR N 1 117 ? 28.591 11.742 74.401 1.00 111.18 ? 117 THR N CA 1 +ATOM 25656 C C . THR N 1 117 ? 27.676 12.309 73.354 1.00 99.83 ? 117 THR N C 1 +ATOM 25657 O O . THR N 1 117 ? 28.087 13.194 72.602 1.00 83.34 ? 117 THR N O 1 +ATOM 25658 C CB . THR N 1 117 ? 28.772 12.775 75.532 1.00 113.87 ? 117 THR N CB 1 +ATOM 25659 O OG1 . THR N 1 117 ? 29.769 12.326 76.456 1.00 90.49 ? 117 THR N OG1 1 +ATOM 25660 C CG2 . THR N 1 117 ? 27.467 12.974 76.285 1.00 122.27 ? 117 THR N CG2 1 +ATOM 25661 N N . ALA N 1 118 ? 26.441 11.819 73.336 1.00 87.34 ? 118 ALA N N 1 +ATOM 25662 C CA . ALA N 1 118 ? 25.504 12.133 72.257 1.00 80.37 ? 118 ALA N CA 1 +ATOM 25663 C C . ALA N 1 118 ? 24.314 12.931 72.725 1.00 79.01 ? 118 ALA N C 1 +ATOM 25664 O O . ALA N 1 118 ? 23.767 12.670 73.809 1.00 139.12 ? 118 ALA N O 1 +ATOM 25665 C CB . ALA N 1 118 ? 25.014 10.864 71.616 1.00 63.91 ? 118 ALA N CB 1 +ATOM 25666 N N . ALA N 1 119 ? 23.870 13.840 71.872 1.00 75.56 ? 119 ALA N N 1 +ATOM 25667 C CA . ALA N 1 119 ? 22.872 14.848 72.253 1.00 109.43 ? 119 ALA N CA 1 +ATOM 25668 C C . ALA N 1 119 ? 21.490 14.346 71.949 1.00 119.55 ? 119 ALA N C 1 +ATOM 25669 O O . ALA N 1 119 ? 21.341 13.484 71.076 1.00 106.24 ? 119 ALA N O 1 +ATOM 25670 C CB . ALA N 1 119 ? 23.116 16.148 71.500 1.00 113.27 ? 119 ALA N CB 1 +ATOM 25671 N N . ASN N 1 120 ? 20.487 14.860 72.670 1.00 114.32 ? 120 ASN N N 1 +ATOM 25672 C CA . ASN N 1 120 ? 19.113 14.496 72.364 1.00 129.92 ? 120 ASN N CA 1 +ATOM 25673 C C . ASN N 1 120 ? 18.413 15.543 71.527 1.00 123.69 ? 120 ASN N C 1 +ATOM 25674 O O . ASN N 1 120 ? 17.707 15.227 70.556 1.00 138.94 ? 120 ASN N O 1 +ATOM 25675 C CB . ASN N 1 120 ? 18.280 14.245 73.611 1.00 157.02 ? 120 ASN N CB 1 +ATOM 25676 C CG . ASN N 1 120 ? 16.864 13.768 73.269 1.00 200.15 ? 120 ASN N CG 1 +ATOM 25677 O OD1 . ASN N 1 120 ? 15.902 14.221 73.882 1.00 269.87 ? 120 ASN N OD1 1 +ATOM 25678 N ND2 . ASN N 1 120 ? 16.721 12.922 72.226 1.00 171.31 ? 120 ASN N ND2 1 +ATOM 25679 N N . ILE N 1 121 ? 18.548 16.796 71.928 1.00 99.86 ? 121 ILE N N 1 +ATOM 25680 C CA . ILE N 1 121 ? 18.024 17.877 71.105 1.00 126.77 ? 121 ILE N CA 1 +ATOM 25681 C C . ILE N 1 121 ? 19.207 18.631 70.545 1.00 144.61 ? 121 ILE N C 1 +ATOM 25682 O O . ILE N 1 121 ? 20.250 18.754 71.186 1.00 162.77 ? 121 ILE N O 1 +ATOM 25683 C CB . ILE N 1 121 ? 17.092 18.841 71.873 1.00 111.37 ? 121 ILE N CB 1 +ATOM 25684 C CG1 . ILE N 1 121 ? 17.875 19.733 72.844 1.00 124.79 ? 121 ILE N CG1 1 +ATOM 25685 C CG2 . ILE N 1 121 ? 16.016 18.058 72.604 1.00 105.04 ? 121 ILE N CG2 1 +ATOM 25686 C CD1 . ILE N 1 121 ? 17.918 21.184 72.429 1.00 124.87 ? 121 ILE N CD1 1 +ATOM 25687 N N . MET N 1 122 ? 19.086 19.059 69.300 1.00 122.52 ? 122 MET N N 1 +ATOM 25688 C CA . MET N 1 122 ? 20.072 19.959 68.782 1.00 84.51 ? 122 MET N CA 1 +ATOM 25689 C C . MET N 1 122 ? 19.345 21.222 68.381 1.00 62.77 ? 122 MET N C 1 +ATOM 25690 O O . MET N 1 122 ? 18.252 21.177 67.870 1.00 51.39 ? 122 MET N O 1 +ATOM 25691 C CB . MET N 1 122 ? 20.898 19.288 67.654 1.00 88.82 ? 122 MET N CB 1 +ATOM 25692 C CG . MET N 1 122 ? 20.119 18.730 66.478 1.00 76.37 ? 122 MET N CG 1 +ATOM 25693 S SD . MET N 1 122 ? 21.183 18.697 65.018 1.00 97.75 ? 122 MET N SD 1 +ATOM 25694 C CE . MET N 1 122 ? 19.991 19.348 63.798 1.00 136.61 ? 122 MET N CE 1 +ATOM 25695 N N . VAL N 1 123 ? 20.006 22.344 68.570 1.00 69.24 ? 123 VAL N N 1 +ATOM 25696 C CA . VAL N 1 123 ? 19.443 23.627 68.194 1.00 79.18 ? 123 VAL N CA 1 +ATOM 25697 C C . VAL N 1 123 ? 20.286 24.336 67.155 1.00 77.71 ? 123 VAL N C 1 +ATOM 25698 O O . VAL N 1 123 ? 21.500 24.484 67.305 1.00 77.97 ? 123 VAL N O 1 +ATOM 25699 C CB . VAL N 1 123 ? 19.334 24.568 69.402 1.00 117.06 ? 123 VAL N CB 1 +ATOM 25700 C CG1 . VAL N 1 123 ? 20.564 24.469 70.297 1.00 127.27 ? 123 VAL N CG1 1 +ATOM 25701 C CG2 . VAL N 1 123 ? 19.097 26.012 68.955 1.00 141.95 ? 123 VAL N CG2 1 +ATOM 25702 N N . GLU N 1 124 ? 19.646 24.736 66.072 1.00 79.23 ? 124 GLU N N 1 +ATOM 25703 C CA . GLU N 1 124 ? 20.327 25.506 65.045 1.00 89.53 ? 124 GLU N CA 1 +ATOM 25704 C C . GLU N 1 124 ? 19.533 26.731 64.745 1.00 80.68 ? 124 GLU N C 1 +ATOM 25705 O O . GLU N 1 124 ? 18.381 26.849 65.126 1.00 98.59 ? 124 GLU N O 1 +ATOM 25706 C CB . GLU N 1 124 ? 20.563 24.689 63.754 1.00 102.50 ? 124 GLU N CB 1 +ATOM 25707 C CG . GLU N 1 124 ? 19.556 23.593 63.456 1.00 100.33 ? 124 GLU N CG 1 +ATOM 25708 C CD . GLU N 1 124 ? 20.085 22.604 62.437 1.00 104.19 ? 124 GLU N CD 1 +ATOM 25709 O OE1 . GLU N 1 124 ? 21.301 22.283 62.475 1.00 135.92 ? 124 GLU N OE1 1 +ATOM 25710 O OE2 . GLU N 1 124 ? 19.285 22.102 61.640 1.00 95.81 ? 124 GLU N OE2 1 +ATOM 25711 N N . GLY N 1 125 ? 20.133 27.608 63.965 1.00 92.61 ? 125 GLY N N 1 +ATOM 25712 C CA . GLY N 1 125 ? 19.506 28.867 63.629 1.00 94.42 ? 125 GLY N CA 1 +ATOM 25713 C C . GLY N 1 125 ? 20.323 29.656 62.616 1.00 80.73 ? 125 GLY N C 1 +ATOM 25714 O O . GLY N 1 125 ? 21.137 29.098 61.884 1.00 60.35 ? 125 GLY N O 1 +ATOM 25715 N N . SER N 1 126 ? 20.053 30.946 62.534 1.00 70.28 ? 126 SER N N 1 +ATOM 25716 C CA . SER N 1 126 ? 20.639 31.754 61.493 1.00 80.83 ? 126 SER N CA 1 +ATOM 25717 C C . SER N 1 126 ? 20.549 33.189 61.904 1.00 96.86 ? 126 SER N C 1 +ATOM 25718 O O . SER N 1 126 ? 19.590 33.597 62.557 1.00 126.07 ? 126 SER N O 1 +ATOM 25719 C CB . SER N 1 126 ? 19.892 31.576 60.172 1.00 93.02 ? 126 SER N CB 1 +ATOM 25720 O OG . SER N 1 126 ? 19.336 30.264 60.009 1.00 133.86 ? 126 SER N OG 1 +ATOM 25721 N N . ILE N 1 127 ? 21.520 33.980 61.491 1.00 96.96 ? 127 ILE N N 1 +ATOM 25722 C CA . ILE N 1 127 ? 21.351 35.417 61.548 1.00 91.57 ? 127 ILE N CA 1 +ATOM 25723 C C . ILE N 1 127 ? 20.489 35.832 60.360 1.00 101.54 ? 127 ILE N C 1 +ATOM 25724 O O . ILE N 1 127 ? 20.942 35.871 59.230 1.00 131.70 ? 127 ILE N O 1 +ATOM 25725 C CB . ILE N 1 127 ? 22.683 36.170 61.526 1.00 98.13 ? 127 ILE N CB 1 +ATOM 25726 C CG1 . ILE N 1 127 ? 23.480 35.878 62.799 1.00 88.58 ? 127 ILE N CG1 1 +ATOM 25727 C CG2 . ILE N 1 127 ? 22.447 37.671 61.387 1.00 108.23 ? 127 ILE N CG2 1 +ATOM 25728 C CD1 . ILE N 1 127 ? 24.991 35.928 62.600 1.00 95.45 ? 127 ILE N CD1 1 +ATOM 25729 N N . ILE N 1 128 ? 19.221 36.091 60.633 1.00 101.37 ? 128 ILE N N 1 +ATOM 25730 C CA . ILE N 1 128 ? 18.231 36.466 59.620 1.00 85.01 ? 128 ILE N CA 1 +ATOM 25731 C C . ILE N 1 128 ? 18.243 37.975 59.641 1.00 80.61 ? 128 ILE N C 1 +ATOM 25732 O O . ILE N 1 128 ? 17.745 38.641 60.557 1.00 135.30 ? 128 ILE N O 1 +ATOM 25733 C CB . ILE N 1 128 ? 16.839 35.863 59.946 1.00 98.81 ? 128 ILE N CB 1 +ATOM 25734 C CG1 . ILE N 1 128 ? 16.410 36.194 61.395 1.00 132.71 ? 128 ILE N CG1 1 +ATOM 25735 C CG2 . ILE N 1 128 ? 16.903 34.347 59.902 1.00 118.07 ? 128 ILE N CG2 1 +ATOM 25736 C CD1 . ILE N 1 128 ? 14.908 36.166 61.600 1.00 126.46 ? 128 ILE N CD1 1 +ATOM 25737 N N . GLY N 1 129 ? 18.964 38.535 58.705 1.00 84.05 ? 129 GLY N N 1 +ATOM 25738 C CA . GLY N 1 129 ? 18.821 39.960 58.426 1.00 105.97 ? 129 GLY N CA 1 +ATOM 25739 C C . GLY N 1 129 ? 19.634 40.953 59.252 1.00 111.32 ? 129 GLY N C 1 +ATOM 25740 O O . GLY N 1 129 ? 19.804 40.829 60.476 1.00 91.40 ? 129 GLY N O 1 +ATOM 25741 N N . TYR N 1 130 ? 20.204 41.910 58.528 1.00 106.35 ? 130 TYR N N 1 +ATOM 25742 C CA . TYR N 1 130 ? 20.772 43.115 59.118 1.00 78.69 ? 130 TYR N CA 1 +ATOM 25743 C C . TYR N 1 130 ? 20.415 44.221 58.158 1.00 101.65 ? 130 TYR N C 1 +ATOM 25744 O O . TYR N 1 130 ? 20.906 44.256 57.035 1.00 125.36 ? 130 TYR N O 1 +ATOM 25745 C CB . TYR N 1 130 ? 22.284 43.004 59.270 1.00 66.84 ? 130 TYR N CB 1 +ATOM 25746 C CG . TYR N 1 130 ? 22.955 44.243 59.753 1.00 59.37 ? 130 TYR N CG 1 +ATOM 25747 C CD1 . TYR N 1 130 ? 23.214 45.297 58.870 1.00 63.77 ? 130 TYR N CD1 1 +ATOM 25748 C CD2 . TYR N 1 130 ? 23.509 44.300 61.026 1.00 68.76 ? 130 TYR N CD2 1 +ATOM 25749 C CE1 . TYR N 1 130 ? 23.901 46.435 59.278 1.00 83.24 ? 130 TYR N CE1 1 +ATOM 25750 C CE2 . TYR N 1 130 ? 24.256 45.405 61.426 1.00 91.30 ? 130 TYR N CE2 1 +ATOM 25751 C CZ . TYR N 1 130 ? 24.445 46.467 60.557 1.00 90.44 ? 130 TYR N CZ 1 +ATOM 25752 O OH . TYR N 1 130 ? 25.054 47.607 61.021 1.00 81.63 ? 130 TYR N OH 1 +ATOM 25753 N N . GLU N 1 131 ? 19.434 45.024 58.531 1.00 129.11 ? 131 GLU N N 1 +ATOM 25754 C CA . GLU N 1 131 ? 19.101 46.207 57.753 1.00 133.35 ? 131 GLU N CA 1 +ATOM 25755 C C . GLU N 1 131 ? 19.806 47.395 58.382 1.00 121.52 ? 131 GLU N C 1 +ATOM 25756 O O . GLU N 1 131 ? 20.064 47.402 59.593 1.00 94.09 ? 131 GLU N O 1 +ATOM 25757 C CB . GLU N 1 131 ? 17.594 46.404 57.745 1.00 175.03 ? 131 GLU N CB 1 +ATOM 25758 C CG . GLU N 1 131 ? 17.090 47.482 56.810 1.00 196.09 ? 131 GLU N CG 1 +ATOM 25759 C CD . GLU N 1 131 ? 16.808 46.999 55.394 1.00 213.16 ? 131 GLU N CD 1 +ATOM 25760 O OE1 . GLU N 1 131 ? 16.522 45.786 55.203 1.00 264.71 ? 131 GLU N OE1 1 +ATOM 25761 O OE2 . GLU N 1 131 ? 16.897 47.840 54.465 1.00 139.93 ? 131 GLU N OE2 1 +ATOM 25762 N N . SER N 1 132 ? 20.250 48.322 57.542 1.00 116.27 ? 132 SER N N 1 +ATOM 25763 C CA . SER N 1 132 ? 21.133 49.388 58.008 1.00 116.72 ? 132 SER N CA 1 +ATOM 25764 C C . SER N 1 132 ? 20.483 50.764 57.845 1.00 145.01 ? 132 SER N C 1 +ATOM 25765 O O . SER N 1 132 ? 19.814 51.023 56.838 1.00 148.41 ? 132 SER N O 1 +ATOM 25766 C CB . SER N 1 132 ? 22.471 49.337 57.268 1.00 109.67 ? 132 SER N CB 1 +ATOM 25767 O OG . SER N 1 132 ? 22.623 50.459 56.418 1.00 125.52 ? 132 SER N OG 1 +ATOM 25768 N N . ASN N 1 133 ? 20.700 51.634 58.835 1.00 166.31 ? 133 ASN N N 1 +ATOM 25769 C CA . ASN N 1 133 ? 20.013 52.925 58.912 1.00 146.53 ? 133 ASN N CA 1 +ATOM 25770 C C . ASN N 1 133 ? 18.512 52.762 58.757 1.00 134.65 ? 133 ASN N C 1 +ATOM 25771 O O . ASN N 1 133 ? 17.904 53.357 57.863 1.00 121.98 ? 133 ASN N O 1 +ATOM 25772 C CB . ASN N 1 133 ? 20.527 53.867 57.822 1.00 137.13 ? 133 ASN N CB 1 +ATOM 25773 C CG . ASN N 1 133 ? 22.027 53.893 57.741 1.00 163.92 ? 133 ASN N CG 1 +ATOM 25774 O OD1 . ASN N 1 133 ? 22.700 53.621 58.719 1.00 176.62 ? 133 ASN N OD1 1 +ATOM 25775 N ND2 . ASN N 1 133 ? 22.557 54.162 56.553 1.00 160.93 ? 133 ASN N ND2 1 +ATOM 25776 N N . VAL N 1 134 ? 17.947 51.898 59.597 1.00 105.52 ? 134 VAL N N 1 +ATOM 25777 C CA . VAL N 1 134 ? 16.530 51.604 59.574 1.00 92.44 ? 134 VAL N CA 1 +ATOM 25778 C C . VAL N 1 134 ? 15.821 52.872 60.029 1.00 120.59 ? 134 VAL N C 1 +ATOM 25779 O O . VAL N 1 134 ? 14.749 53.222 59.508 1.00 180.18 ? 134 VAL N O 1 +ATOM 25780 C CB . VAL N 1 134 ? 16.183 50.416 60.496 1.00 86.47 ? 134 VAL N CB 1 +ATOM 25781 C CG1 . VAL N 1 134 ? 14.708 50.071 60.432 1.00 84.25 ? 134 VAL N CG1 1 +ATOM 25782 C CG2 . VAL N 1 134 ? 17.007 49.193 60.120 1.00 95.78 ? 134 VAL N CG2 1 +ATOM 25783 N N . LYS N 1 135 ? 16.455 53.596 60.949 1.00 116.33 ? 135 LYS N N 1 +ATOM 25784 C CA . LYS N 1 135 ? 16.090 54.991 61.197 1.00 118.04 ? 135 LYS N CA 1 +ATOM 25785 C C . LYS N 1 135 ? 17.326 55.873 61.320 1.00 128.32 ? 135 LYS N C 1 +ATOM 25786 O O . LYS N 1 135 ? 18.434 55.406 61.618 1.00 168.14 ? 135 LYS N O 1 +ATOM 25787 C CB . LYS N 1 135 ? 15.259 55.102 62.468 1.00 118.26 ? 135 LYS N CB 1 +ATOM 25788 C CG . LYS N 1 135 ? 13.938 54.360 62.395 1.00 137.92 ? 135 LYS N CG 1 +ATOM 25789 C CD . LYS N 1 135 ? 13.222 54.415 63.732 1.00 164.67 ? 135 LYS N CD 1 +ATOM 25790 C CE . LYS N 1 135 ? 11.901 53.675 63.696 1.00 173.22 ? 135 LYS N CE 1 +ATOM 25791 N NZ . LYS N 1 135 ? 11.009 54.149 64.788 1.00 147.41 ? 135 LYS N NZ 1 +ATOM 25792 N N . SER N 1 136 ? 17.116 57.168 61.138 1.00 131.51 ? 136 SER N N 1 +ATOM 25793 C CA . SER N 1 136 ? 18.194 58.139 61.258 1.00 147.63 ? 136 SER N CA 1 +ATOM 25794 C C . SER N 1 136 ? 17.642 59.546 61.404 1.00 154.06 ? 136 SER N C 1 +ATOM 25795 O O . SER N 1 136 ? 16.516 59.830 60.987 1.00 168.72 ? 136 SER N O 1 +ATOM 25796 C CB . SER N 1 136 ? 19.141 58.053 60.057 1.00 149.30 ? 136 SER N CB 1 +ATOM 25797 O OG . SER N 1 136 ? 19.280 59.310 59.410 1.00 190.56 ? 136 SER N OG 1 +ATOM 25798 N N . GLY N 1 137 ? 18.445 60.429 61.984 1.00 150.61 ? 137 GLY N N 1 +ATOM 25799 C CA . GLY N 1 137 ? 18.043 61.820 62.140 1.00 159.90 ? 137 GLY N CA 1 +ATOM 25800 C C . GLY N 1 137 ? 19.177 62.731 62.557 1.00 166.30 ? 137 GLY N C 1 +ATOM 25801 O O . GLY N 1 137 ? 20.296 62.281 62.792 1.00 148.20 ? 137 GLY N O 1 +ATOM 25802 N N . GLY N 1 138 ? 18.897 64.030 62.593 1.00 186.20 ? 138 GLY N N 1 +ATOM 25803 C CA . GLY N 1 138 ? 19.906 65.011 62.964 1.00 189.26 ? 138 GLY N CA 1 +ATOM 25804 C C . GLY N 1 138 ? 19.311 66.361 63.284 1.00 206.49 ? 138 GLY N C 1 +ATOM 25805 O O . GLY N 1 138 ? 18.317 66.774 62.681 1.00 264.82 ? 138 GLY N O 1 +ATOM 25806 N N . VAL N 1 139 ? 19.910 67.041 64.258 1.00 201.23 ? 139 VAL N N 1 +ATOM 25807 C CA . VAL N 1 139 ? 19.492 68.394 64.641 1.00 167.45 ? 139 VAL N CA 1 +ATOM 25808 C C . VAL N 1 139 ? 20.706 69.271 64.915 1.00 159.44 ? 139 VAL N C 1 +ATOM 25809 O O . VAL N 1 139 ? 21.576 68.904 65.705 1.00 166.83 ? 139 VAL N O 1 +ATOM 25810 C CB . VAL N 1 139 ? 18.614 68.396 65.903 1.00 130.47 ? 139 VAL N CB 1 +ATOM 25811 C CG1 . VAL N 1 139 ? 18.324 69.822 66.324 1.00 115.71 ? 139 VAL N CG1 1 +ATOM 25812 C CG2 . VAL N 1 139 ? 17.320 67.624 65.665 1.00 142.96 ? 139 VAL N CG2 1 +ATOM 25813 N N . GLY N 1 140 ? 20.772 70.410 64.228 1.00 175.96 ? 140 GLY N N 1 +ATOM 25814 C CA . GLY N 1 140 ? 21.915 71.307 64.332 1.00 176.08 ? 140 GLY N CA 1 +ATOM 25815 C C . GLY N 1 140 ? 21.580 72.762 64.085 1.00 176.17 ? 140 GLY N C 1 +ATOM 25816 O O . GLY N 1 140 ? 20.732 73.090 63.249 1.00 172.18 ? 140 GLY N O 1 +ATOM 25817 N N . ALA N 1 141 ? 22.234 73.640 64.835 1.00 179.67 ? 141 ALA N N 1 +ATOM 25818 C CA . ALA N 1 141 ? 21.994 75.072 64.714 1.00 165.80 ? 141 ALA N CA 1 +ATOM 25819 C C . ALA N 1 141 ? 23.273 75.869 64.916 1.00 162.30 ? 141 ALA N C 1 +ATOM 25820 O O . ALA N 1 141 ? 24.109 75.538 65.763 1.00 187.29 ? 141 ALA N O 1 +ATOM 25821 C CB . ALA N 1 141 ? 20.913 75.518 65.692 1.00 141.83 ? 141 ALA N CB 1 +ATOM 25822 N N . ARG N 1 142 ? 23.440 76.891 64.093 1.00 171.88 ? 142 ARG N N 1 +ATOM 25823 C CA . ARG N 1 142 ? 24.540 77.812 64.261 1.00 183.86 ? 142 ARG N CA 1 +ATOM 25824 C C . ARG N 1 142 ? 23.994 79.235 64.259 1.00 198.72 ? 142 ARG N C 1 +ATOM 25825 O O . ARG N 1 142 ? 23.018 79.537 63.571 1.00 152.19 ? 142 ARG N O 1 +ATOM 25826 C CB . ARG N 1 142 ? 25.595 77.629 63.165 1.00 164.25 ? 142 ARG N CB 1 +ATOM 25827 C CG . ARG N 1 142 ? 26.810 78.522 63.364 1.00 143.89 ? 142 ARG N CG 1 +ATOM 25828 C CD . ARG N 1 142 ? 28.094 77.795 63.068 1.00 156.40 ? 142 ARG N CD 1 +ATOM 25829 N NE . ARG N 1 142 ? 28.262 77.701 61.625 1.00 178.69 ? 142 ARG N NE 1 +ATOM 25830 C CZ . ARG N 1 142 ? 28.941 76.736 61.009 1.00 194.69 ? 142 ARG N CZ 1 +ATOM 25831 N NH1 . ARG N 1 142 ? 29.622 75.823 61.699 1.00 192.80 ? 142 ARG N NH1 1 +ATOM 25832 N NH2 . ARG N 1 142 ? 29.008 76.729 59.683 1.00 199.57 ? 142 ARG N NH2 1 +ATOM 25833 N N . TYR N 1 143 ? 24.605 80.087 65.080 1.00 228.02 ? 143 TYR N N 1 +ATOM 25834 C CA . TYR N 1 143 ? 24.105 81.442 65.325 1.00 200.43 ? 143 TYR N CA 1 +ATOM 25835 C C . TYR N 1 143 ? 25.230 82.477 65.176 1.00 177.44 ? 143 TYR N C 1 +ATOM 25836 O O . TYR N 1 143 ? 25.853 82.900 66.151 1.00 114.09 ? 143 TYR N O 1 +ATOM 25837 C CB . TYR N 1 143 ? 23.468 81.525 66.726 1.00 186.74 ? 143 TYR N CB 1 +ATOM 25838 C CG . TYR N 1 143 ? 22.819 82.844 66.994 1.00 183.76 ? 143 TYR N CG 1 +ATOM 25839 C CD1 . TYR N 1 143 ? 21.671 83.215 66.311 1.00 190.35 ? 143 TYR N CD1 1 +ATOM 25840 C CD2 . TYR N 1 143 ? 23.414 83.769 67.834 1.00 183.40 ? 143 TYR N CD2 1 +ATOM 25841 C CE1 . TYR N 1 143 ? 21.113 84.468 66.483 1.00 190.67 ? 143 TYR N CE1 1 +ATOM 25842 C CE2 . TYR N 1 143 ? 22.861 85.022 68.024 1.00 200.60 ? 143 TYR N CE2 1 +ATOM 25843 C CZ . TYR N 1 143 ? 21.710 85.367 67.344 1.00 197.97 ? 143 TYR N CZ 1 +ATOM 25844 O OH . TYR N 1 143 ? 21.152 86.611 67.521 1.00 205.03 ? 143 TYR N OH 1 +ATOM 25845 N N . GLY N 1 145 ? 27.913 82.795 65.053 1.00 178.49 ? 145 GLY N N 1 +ATOM 25846 C CA . GLY N 1 145 ? 29.293 82.365 65.273 1.00 191.15 ? 145 GLY N CA 1 +ATOM 25847 C C . GLY N 1 145 ? 29.438 81.062 66.050 1.00 201.00 ? 145 GLY N C 1 +ATOM 25848 O O . GLY N 1 145 ? 30.435 80.364 65.894 1.00 174.36 ? 145 GLY N O 1 +ATOM 25849 N N . ILE N 1 146 ? 28.408 80.685 66.811 1.00 210.33 ? 146 ILE N N 1 +ATOM 25850 C CA . ILE N 1 146 ? 28.465 79.508 67.698 1.00 176.03 ? 146 ILE N CA 1 +ATOM 25851 C C . ILE N 1 146 ? 27.480 78.439 67.204 1.00 161.05 ? 146 ILE N C 1 +ATOM 25852 O O . ILE N 1 146 ? 26.357 78.764 66.824 1.00 208.21 ? 146 ILE N O 1 +ATOM 25853 C CB . ILE N 1 146 ? 28.128 79.888 69.163 1.00 152.73 ? 146 ILE N CB 1 +ATOM 25854 C CG1 . ILE N 1 146 ? 28.745 81.246 69.517 1.00 146.23 ? 146 ILE N CG1 1 +ATOM 25855 C CG2 . ILE N 1 146 ? 28.622 78.818 70.128 1.00 150.79 ? 146 ILE N CG2 1 +ATOM 25856 C CD1 . ILE N 1 146 ? 27.787 82.414 69.387 1.00 137.29 ? 146 ILE N CD1 1 +ATOM 25857 N N . GLY N 1 147 ? 27.888 77.171 67.206 1.00 147.88 ? 147 GLY N N 1 +ATOM 25858 C CA . GLY N 1 147 ? 27.025 76.113 66.679 1.00 143.67 ? 147 GLY N CA 1 +ATOM 25859 C C . GLY N 1 147 ? 27.195 74.734 67.291 1.00 147.29 ? 147 GLY N C 1 +ATOM 25860 O O . GLY N 1 147 ? 28.242 74.398 67.837 1.00 131.70 ? 147 GLY N O 1 +ATOM 25861 N N . ALA N 1 148 ? 26.141 73.933 67.202 1.00 165.48 ? 148 ALA N N 1 +ATOM 25862 C CA . ALA N 1 148 ? 26.209 72.538 67.607 1.00 166.03 ? 148 ALA N CA 1 +ATOM 25863 C C . ALA N 1 148 ? 25.295 71.692 66.733 1.00 178.06 ? 148 ALA N C 1 +ATOM 25864 O O . ALA N 1 148 ? 24.467 72.218 65.982 1.00 148.12 ? 148 ALA N O 1 +ATOM 25865 C CB . ALA N 1 148 ? 25.851 72.389 69.081 1.00 132.25 ? 148 ALA N CB 1 +ATOM 25866 N N . ASP N 1 149 ? 25.474 70.378 66.813 1.00 201.78 ? 149 ASP N N 1 +ATOM 25867 C CA . ASP N 1 149 ? 24.612 69.453 66.097 1.00 194.22 ? 149 ASP N CA 1 +ATOM 25868 C C . ASP N 1 149 ? 24.771 68.031 66.628 1.00 166.01 ? 149 ASP N C 1 +ATOM 25869 O O . ASP N 1 149 ? 25.849 67.645 67.089 1.00 142.83 ? 149 ASP N O 1 +ATOM 25870 C CB . ASP N 1 149 ? 24.894 69.506 64.591 1.00 205.15 ? 149 ASP N CB 1 +ATOM 25871 C CG . ASP N 1 149 ? 26.098 68.703 64.200 1.00 224.64 ? 149 ASP N CG 1 +ATOM 25872 O OD1 . ASP N 1 149 ? 27.223 69.166 64.468 1.00 216.64 ? 149 ASP N OD1 1 +ATOM 25873 O OD2 . ASP N 1 149 ? 25.916 67.613 63.626 1.00 235.28 ? 149 ASP N OD2 1 +ATOM 25874 N N . THR N 1 150 ? 23.686 67.267 66.596 1.00 159.37 ? 150 THR N N 1 +ATOM 25875 C CA . THR N 1 150 ? 23.789 65.824 66.766 1.00 162.64 ? 150 THR N CA 1 +ATOM 25876 C C . THR N 1 150 ? 23.207 65.119 65.553 1.00 158.59 ? 150 THR N C 1 +ATOM 25877 O O . THR N 1 150 ? 22.369 65.667 64.835 1.00 123.15 ? 150 THR N O 1 +ATOM 25878 C CB . THR N 1 150 ? 23.078 65.312 68.040 1.00 145.48 ? 150 THR N CB 1 +ATOM 25879 O OG1 . THR N 1 150 ? 21.694 65.654 67.985 1.00 147.48 ? 150 THR N OG1 1 +ATOM 25880 C CG2 . THR N 1 150 ? 23.701 65.897 69.282 1.00 128.11 ? 150 THR N CG2 1 +ATOM 25881 N N . GLN N 1 151 ? 23.681 63.904 65.330 1.00 149.97 ? 151 GLN N N 1 +ATOM 25882 C CA . GLN N 1 151 ? 23.142 63.046 64.315 1.00 156.35 ? 151 GLN N CA 1 +ATOM 25883 C C . GLN N 1 151 ? 23.058 61.647 64.878 1.00 149.41 ? 151 GLN N C 1 +ATOM 25884 O O . GLN N 1 151 ? 23.923 61.231 65.627 1.00 134.28 ? 151 GLN N O 1 +ATOM 25885 C CB . GLN N 1 151 ? 24.062 63.073 63.096 1.00 185.23 ? 151 GLN N CB 1 +ATOM 25886 C CG . GLN N 1 151 ? 23.980 64.375 62.327 1.00 182.53 ? 151 GLN N CG 1 +ATOM 25887 C CD . GLN N 1 151 ? 25.211 64.611 61.485 1.00 186.36 ? 151 GLN N CD 1 +ATOM 25888 O OE1 . GLN N 1 151 ? 25.726 63.681 60.867 1.00 164.21 ? 151 GLN N OE1 1 +ATOM 25889 N NE2 . GLN N 1 151 ? 25.691 65.853 61.453 1.00 188.25 ? 151 GLN N NE2 1 +ATOM 25890 N N . TYR N 1 152 ? 22.032 60.900 64.495 1.00 162.68 ? 152 TYR N N 1 +ATOM 25891 C CA . TYR N 1 152 ? 21.933 59.515 64.924 1.00 155.51 ? 152 TYR N CA 1 +ATOM 25892 C C . TYR N 1 152 ? 21.504 58.591 63.800 1.00 150.52 ? 152 TYR N C 1 +ATOM 25893 O O . TYR N 1 152 ? 20.721 58.981 62.938 1.00 139.10 ? 152 TYR N O 1 +ATOM 25894 C CB . TYR N 1 152 ? 20.995 59.406 66.125 1.00 122.93 ? 152 TYR N CB 1 +ATOM 25895 C CG . TYR N 1 152 ? 19.623 58.819 65.855 1.00 82.97 ? 152 TYR N CG 1 +ATOM 25896 C CD1 . TYR N 1 152 ? 18.712 59.467 65.033 1.00 70.56 ? 152 TYR N CD1 1 +ATOM 25897 C CD2 . TYR N 1 152 ? 19.204 57.692 66.538 1.00 80.81 ? 152 TYR N CD2 1 +ATOM 25898 C CE1 . TYR N 1 152 ? 17.437 58.973 64.847 1.00 76.95 ? 152 TYR N CE1 1 +ATOM 25899 C CE2 . TYR N 1 152 ? 17.915 57.220 66.413 1.00 86.25 ? 152 TYR N CE2 1 +ATOM 25900 C CZ . TYR N 1 152 ? 17.037 57.861 65.563 1.00 88.98 ? 152 TYR N CZ 1 +ATOM 25901 O OH . TYR N 1 152 ? 15.743 57.403 65.472 1.00 101.60 ? 152 TYR N OH 1 +ATOM 25902 N N . GLN N 1 153 ? 22.007 57.366 63.841 1.00 121.04 ? 153 GLN N N 1 +ATOM 25903 C CA . GLN N 1 153 ? 21.451 56.327 63.013 1.00 126.53 ? 153 GLN N CA 1 +ATOM 25904 C C . GLN N 1 153 ? 21.212 55.054 63.823 1.00 104.97 ? 153 GLN N C 1 +ATOM 25905 O O . GLN N 1 153 ? 21.893 54.819 64.821 1.00 81.68 ? 153 GLN N O 1 +ATOM 25906 C CB . GLN N 1 153 ? 22.342 55.966 61.846 1.00 132.57 ? 153 GLN N CB 1 +ATOM 25907 C CG . GLN N 1 153 ? 23.765 55.477 62.168 1.00 138.23 ? 153 GLN N CG 1 +ATOM 25908 C CD . GLN N 1 153 ? 24.353 54.527 61.123 1.00 108.07 ? 153 GLN N CD 1 +ATOM 25909 O OE1 . GLN N 1 153 ? 24.823 53.381 61.382 1.00 75.05 ? 153 GLN N OE1 1 +ATOM 25910 N NE2 . GLN N 1 153 ? 24.356 55.018 59.927 1.00 102.13 ? 153 GLN N NE2 1 +ATOM 25911 N N . LEU N 1 154 ? 20.286 54.210 63.359 1.00 96.54 ? 154 LEU N N 1 +ATOM 25912 C CA . LEU N 1 154 ? 20.144 52.891 63.946 1.00 107.15 ? 154 LEU N CA 1 +ATOM 25913 C C . LEU N 1 154 ? 19.806 51.794 62.933 1.00 104.02 ? 154 LEU N C 1 +ATOM 25914 O O . LEU N 1 154 ? 19.037 52.011 61.978 1.00 87.17 ? 154 LEU N O 1 +ATOM 25915 C CB . LEU N 1 154 ? 19.111 52.923 65.071 1.00 102.88 ? 154 LEU N CB 1 +ATOM 25916 C CG . LEU N 1 154 ? 17.654 53.065 64.635 1.00 130.45 ? 154 LEU N CG 1 +ATOM 25917 C CD1 . LEU N 1 154 ? 16.962 51.715 64.529 1.00 126.62 ? 154 LEU N CD1 1 +ATOM 25918 C CD2 . LEU N 1 154 ? 16.930 53.982 65.607 1.00 178.77 ? 154 LEU N CD2 1 +ATOM 25919 N N . ASP N 1 155 ? 20.308 50.594 63.247 1.00 92.45 ? 155 ASP N N 1 +ATOM 25920 C CA . ASP N 1 155 ? 20.294 49.437 62.360 1.00 84.20 ? 155 ASP N CA 1 +ATOM 25921 C C . ASP N 1 155 ? 19.585 48.290 63.054 1.00 91.49 ? 155 ASP N C 1 +ATOM 25922 O O . ASP N 1 155 ? 19.415 48.311 64.275 1.00 91.82 ? 155 ASP N O 1 +ATOM 25923 C CB . ASP N 1 155 ? 21.724 49.023 62.045 1.00 88.20 ? 155 ASP N CB 1 +ATOM 25924 C CG . ASP N 1 155 ? 22.589 50.205 61.648 1.00 98.39 ? 155 ASP N CG 1 +ATOM 25925 O OD1 . ASP N 1 155 ? 23.073 50.926 62.553 1.00 94.06 ? 155 ASP N OD1 1 +ATOM 25926 O OD2 . ASP N 1 155 ? 22.838 50.392 60.431 1.00 97.58 ? 155 ASP N OD2 1 +ATOM 25927 N N . GLN N 1 156 ? 19.145 47.297 62.283 1.00 96.93 ? 156 GLN N N 1 +ATOM 25928 C CA . GLN N 1 156 ? 18.436 46.147 62.860 1.00 113.12 ? 156 GLN N CA 1 +ATOM 25929 C C . GLN N 1 156 ? 19.207 44.839 62.648 1.00 112.49 ? 156 GLN N C 1 +ATOM 25930 O O . GLN N 1 156 ? 20.032 44.741 61.759 1.00 97.74 ? 156 GLN N O 1 +ATOM 25931 C CB . GLN N 1 156 ? 17.033 46.028 62.262 1.00 121.52 ? 156 GLN N CB 1 +ATOM 25932 C CG . GLN N 1 156 ? 16.121 45.045 62.981 1.00 115.13 ? 156 GLN N CG 1 +ATOM 25933 C CD . GLN N 1 156 ? 14.647 45.281 62.675 1.00 102.03 ? 156 GLN N CD 1 +ATOM 25934 O OE1 . GLN N 1 156 ? 14.291 46.098 61.813 1.00 72.81 ? 156 GLN N OE1 1 +ATOM 25935 N NE2 . GLN N 1 156 ? 13.781 44.566 63.387 1.00 99.30 ? 156 GLN N NE2 1 +ATOM 25936 N N . ILE N 1 157 ? 18.958 43.862 63.515 1.00 106.48 ? 157 ILE N N 1 +ATOM 25937 C CA . ILE N 1 157 ? 19.577 42.552 63.396 1.00 89.77 ? 157 ILE N CA 1 +ATOM 25938 C C . ILE N 1 157 ? 18.619 41.530 63.996 1.00 84.67 ? 157 ILE N C 1 +ATOM 25939 O O . ILE N 1 157 ? 17.962 41.799 65.020 1.00 100.54 ? 157 ILE N O 1 +ATOM 25940 C CB . ILE N 1 157 ? 20.948 42.519 64.101 1.00 77.40 ? 157 ILE N CB 1 +ATOM 25941 C CG1 . ILE N 1 157 ? 21.824 41.427 63.515 1.00 64.20 ? 157 ILE N CG1 1 +ATOM 25942 C CG2 . ILE N 1 157 ? 20.773 42.312 65.607 1.00 78.70 ? 157 ILE N CG2 1 +ATOM 25943 C CD1 . ILE N 1 157 ? 23.253 41.443 64.022 1.00 66.53 ? 157 ILE N CD1 1 +ATOM 25944 N N . ALA N 1 158 ? 18.461 40.398 63.331 1.00 70.23 ? 158 ALA N N 1 +ATOM 25945 C CA . ALA N 1 158 ? 17.509 39.421 63.814 1.00 75.34 ? 158 ALA N CA 1 +ATOM 25946 C C . ALA N 1 158 ? 18.130 38.068 63.801 1.00 79.13 ? 158 ALA N C 1 +ATOM 25947 O O . ALA N 1 158 ? 19.021 37.780 63.000 1.00 110.28 ? 158 ALA N O 1 +ATOM 25948 C CB . ALA N 1 158 ? 16.216 39.445 63.001 1.00 74.02 ? 158 ALA N CB 1 +ATOM 25949 N N . VAL N 1 159 ? 17.667 37.223 64.711 1.00 85.13 ? 159 VAL N N 1 +ATOM 25950 C CA . VAL N 1 159 ? 18.238 35.905 64.872 1.00 114.68 ? 159 VAL N CA 1 +ATOM 25951 C C . VAL N 1 159 ? 17.137 34.868 65.029 1.00 136.49 ? 159 VAL N C 1 +ATOM 25952 O O . VAL N 1 159 ? 16.243 35.006 65.864 1.00 194.54 ? 159 VAL N O 1 +ATOM 25953 C CB . VAL N 1 159 ? 19.205 35.871 66.071 1.00 103.83 ? 159 VAL N CB 1 +ATOM 25954 C CG1 . VAL N 1 159 ? 19.440 34.451 66.552 1.00 100.98 ? 159 VAL N CG1 1 +ATOM 25955 C CG2 . VAL N 1 159 ? 20.530 36.508 65.689 1.00 125.00 ? 159 VAL N CG2 1 +ATOM 25956 N N . ASN N 1 160 ? 17.230 33.805 64.236 1.00 118.13 ? 160 ASN N N 1 +ATOM 25957 C CA . ASN N 1 160 ? 16.421 32.617 64.438 1.00 112.54 ? 160 ASN N CA 1 +ATOM 25958 C C . ASN N 1 160 ? 17.233 31.600 65.250 1.00 87.28 ? 160 ASN N C 1 +ATOM 25959 O O . ASN N 1 160 ? 18.382 31.315 64.923 1.00 69.74 ? 160 ASN N O 1 +ATOM 25960 C CB . ASN N 1 160 ? 16.017 32.043 63.079 1.00 115.81 ? 160 ASN N CB 1 +ATOM 25961 C CG . ASN N 1 160 ? 15.204 30.751 63.181 1.00 128.73 ? 160 ASN N CG 1 +ATOM 25962 O OD1 . ASN N 1 160 ? 15.577 29.799 63.876 1.00 97.69 ? 160 ASN N OD1 1 +ATOM 25963 N ND2 . ASN N 1 160 ? 14.145 30.672 62.388 1.00 136.54 ? 160 ASN N ND2 1 +ATOM 25964 N N . LEU N 1 161 ? 16.628 31.072 66.320 1.00 79.42 ? 161 LEU N N 1 +ATOM 25965 C CA . LEU N 1 161 ? 17.090 29.818 66.947 1.00 75.40 ? 161 LEU N CA 1 +ATOM 25966 C C . LEU N 1 161 ? 15.971 28.800 67.031 1.00 68.95 ? 161 LEU N C 1 +ATOM 25967 O O . LEU N 1 161 ? 14.796 29.152 67.086 1.00 96.22 ? 161 LEU N O 1 +ATOM 25968 C CB . LEU N 1 161 ? 17.579 30.071 68.347 1.00 65.88 ? 161 LEU N CB 1 +ATOM 25969 C CG . LEU N 1 161 ? 18.791 30.980 68.464 1.00 78.62 ? 161 LEU N CG 1 +ATOM 25970 C CD1 . LEU N 1 161 ? 19.042 31.315 69.921 1.00 72.06 ? 161 LEU N CD1 1 +ATOM 25971 C CD2 . LEU N 1 161 ? 19.996 30.310 67.828 1.00 87.13 ? 161 LEU N CD2 1 +ATOM 25972 N N . ARG N 1 162 ? 16.304 27.536 66.884 1.00 63.59 ? 162 ARG N N 1 +ATOM 25973 C CA . ARG N 1 162 ? 15.254 26.528 66.843 1.00 69.03 ? 162 ARG N CA 1 +ATOM 25974 C C . ARG N 1 162 ? 15.711 25.157 67.310 1.00 84.20 ? 162 ARG N C 1 +ATOM 25975 O O . ARG N 1 162 ? 16.758 24.648 66.886 1.00 104.97 ? 162 ARG N O 1 +ATOM 25976 C CB . ARG N 1 162 ? 14.585 26.443 65.454 1.00 74.28 ? 162 ARG N CB 1 +ATOM 25977 C CG . ARG N 1 162 ? 15.453 26.010 64.285 1.00 88.95 ? 162 ARG N CG 1 +ATOM 25978 C CD . ARG N 1 162 ? 14.578 25.567 63.124 1.00 103.86 ? 162 ARG N CD 1 +ATOM 25979 N NE . ARG N 1 162 ? 15.331 24.954 62.032 1.00 131.46 ? 162 ARG N NE 1 +ATOM 25980 C CZ . ARG N 1 162 ? 15.962 25.622 61.074 1.00 133.58 ? 162 ARG N CZ 1 +ATOM 25981 N NH1 . ARG N 1 162 ? 16.062 26.943 61.125 1.00 107.14 ? 162 ARG N NH1 1 +ATOM 25982 N NH2 . ARG N 1 162 ? 16.551 24.947 60.088 1.00 169.67 ? 162 ARG N NH2 1 +ATOM 25983 N N . VAL N 1 163 ? 14.915 24.575 68.203 1.00 104.87 ? 163 VAL N N 1 +ATOM 25984 C CA . VAL N 1 163 ? 15.187 23.261 68.786 1.00 133.51 ? 163 VAL N CA 1 +ATOM 25985 C C . VAL N 1 163 ? 14.621 22.189 67.888 1.00 126.11 ? 163 VAL N C 1 +ATOM 25986 O O . VAL N 1 163 ? 13.414 22.155 67.665 1.00 169.35 ? 163 VAL N O 1 +ATOM 25987 C CB . VAL N 1 163 ? 14.511 23.078 70.163 1.00 126.00 ? 163 VAL N CB 1 +ATOM 25988 C CG1 . VAL N 1 163 ? 14.802 21.672 70.700 1.00 98.63 ? 163 VAL N CG1 1 +ATOM 25989 C CG2 . VAL N 1 163 ? 14.964 24.174 71.127 1.00 131.13 ? 163 VAL N CG2 1 +ATOM 25990 N N . VAL N 1 164 ? 15.492 21.277 67.459 1.00 82.90 ? 164 VAL N N 1 +ATOM 25991 C CA . VAL N 1 164 ? 15.109 20.145 66.610 1.00 54.84 ? 164 VAL N CA 1 +ATOM 25992 C C . VAL N 1 164 ? 15.294 18.858 67.358 1.00 53.30 ? 164 VAL N C 1 +ATOM 25993 O O . VAL N 1 164 ? 16.298 18.697 68.089 1.00 81.19 ? 164 VAL N O 1 +ATOM 25994 C CB . VAL N 1 164 ? 15.980 20.059 65.381 1.00 51.47 ? 164 VAL N CB 1 +ATOM 25995 C CG1 . VAL N 1 164 ? 15.601 18.866 64.553 1.00 44.91 ? 164 VAL N CG1 1 +ATOM 25996 C CG2 . VAL N 1 164 ? 15.856 21.329 64.580 1.00 59.76 ? 164 VAL N CG2 1 +ATOM 25997 N N . ASN N 1 165 ? 14.293 17.994 67.267 1.00 46.55 ? 165 ASN N N 1 +ATOM 25998 C CA . ASN N 1 165 ? 14.353 16.752 67.998 1.00 64.19 ? 165 ASN N CA 1 +ATOM 25999 C C . ASN N 1 165 ? 15.100 15.722 67.188 1.00 81.53 ? 165 ASN N C 1 +ATOM 26000 O O . ASN N 1 165 ? 14.675 15.389 66.060 1.00 111.12 ? 165 ASN N O 1 +ATOM 26001 C CB . ASN N 1 165 ? 12.963 16.230 68.305 1.00 77.33 ? 165 ASN N CB 1 +ATOM 26002 C CG . ASN N 1 165 ? 13.002 15.011 69.222 1.00 104.67 ? 165 ASN N CG 1 +ATOM 26003 O OD1 . ASN N 1 165 ? 14.051 14.651 69.760 1.00 64.57 ? 165 ASN N OD1 1 +ATOM 26004 N ND2 . ASN N 1 165 ? 11.873 14.320 69.333 1.00 133.30 ? 165 ASN N ND2 1 +ATOM 26005 N N . VAL N 1 166 ? 16.196 15.203 67.745 1.00 82.95 ? 166 VAL N N 1 +ATOM 26006 C CA . VAL N 1 166 ? 17.069 14.262 67.018 1.00 112.67 ? 166 VAL N CA 1 +ATOM 26007 C C . VAL N 1 166 ? 16.325 12.987 66.670 1.00 108.37 ? 166 VAL N C 1 +ATOM 26008 O O . VAL N 1 166 ? 16.463 12.472 65.572 1.00 82.63 ? 166 VAL N O 1 +ATOM 26009 C CB . VAL N 1 166 ? 18.313 13.889 67.849 1.00 116.22 ? 166 VAL N CB 1 +ATOM 26010 C CG1 . VAL N 1 166 ? 18.888 12.524 67.448 1.00 83.12 ? 166 VAL N CG1 1 +ATOM 26011 C CG2 . VAL N 1 166 ? 19.349 15.009 67.753 1.00 137.30 ? 166 VAL N CG2 1 +ATOM 26012 N N . SER N 1 167 ? 15.456 12.568 67.580 1.00 109.01 ? 167 SER N N 1 +ATOM 26013 C CA . SER N 1 167 ? 14.776 11.300 67.451 1.00 119.48 ? 167 SER N CA 1 +ATOM 26014 C C . SER N 1 167 ? 13.696 11.300 66.362 1.00 132.93 ? 167 SER N C 1 +ATOM 26015 O O . SER N 1 167 ? 13.231 10.236 65.966 1.00 137.78 ? 167 SER N O 1 +ATOM 26016 C CB . SER N 1 167 ? 14.173 10.922 68.794 1.00 152.05 ? 167 SER N CB 1 +ATOM 26017 O OG . SER N 1 167 ? 15.109 11.144 69.843 1.00 217.53 ? 167 SER N OG 1 +ATOM 26018 N N . THR N 1 168 ? 13.325 12.481 65.851 1.00 144.92 ? 168 THR N N 1 +ATOM 26019 C CA . THR N 1 168 ? 12.266 12.585 64.832 1.00 119.07 ? 168 THR N CA 1 +ATOM 26020 C C . THR N 1 168 ? 12.576 13.555 63.681 1.00 89.09 ? 168 THR N C 1 +ATOM 26021 O O . THR N 1 168 ? 12.103 13.388 62.557 1.00 75.19 ? 168 THR N O 1 +ATOM 26022 C CB . THR N 1 168 ? 10.930 13.004 65.480 1.00 129.62 ? 168 THR N CB 1 +ATOM 26023 O OG1 . THR N 1 168 ? 11.127 14.179 66.279 1.00 116.80 ? 168 THR N OG1 1 +ATOM 26024 C CG2 . THR N 1 168 ? 10.380 11.870 66.357 1.00 146.17 ? 168 THR N CG2 1 +ATOM 26025 N N . GLY N 1 169 ? 13.266 14.631 63.994 1.00 68.02 ? 169 GLY N N 1 +ATOM 26026 C CA . GLY N 1 169 ? 13.377 15.694 63.045 1.00 80.38 ? 169 GLY N CA 1 +ATOM 26027 C C . GLY N 1 169 ? 12.298 16.748 63.204 1.00 103.08 ? 169 GLY N C 1 +ATOM 26028 O O . GLY N 1 169 ? 12.376 17.825 62.593 1.00 110.51 ? 169 GLY N O 1 +ATOM 26029 N N . GLU N 1 170 ? 11.292 16.470 64.032 1.00 115.59 ? 170 GLU N N 1 +ATOM 26030 C CA . GLU N 1 170 ? 10.316 17.501 64.416 1.00 135.27 ? 170 GLU N CA 1 +ATOM 26031 C C . GLU N 1 170 ? 11.066 18.672 65.018 1.00 133.83 ? 170 GLU N C 1 +ATOM 26032 O O . GLU N 1 170 ? 11.904 18.497 65.879 1.00 124.64 ? 170 GLU N O 1 +ATOM 26033 C CB . GLU N 1 170 ? 9.301 16.977 65.452 1.00 138.84 ? 170 GLU N CB 1 +ATOM 26034 C CG . GLU N 1 170 ? 8.200 16.096 64.870 1.00 158.40 ? 170 GLU N CG 1 +ATOM 26035 C CD . GLU N 1 170 ? 7.781 14.941 65.767 1.00 152.06 ? 170 GLU N CD 1 +ATOM 26036 O OE1 . GLU N 1 170 ? 8.472 14.680 66.770 1.00 145.74 ? 170 GLU N OE1 1 +ATOM 26037 O OE2 . GLU N 1 170 ? 6.787 14.253 65.434 1.00 148.79 ? 170 GLU N OE2 1 +ATOM 26038 N N . ILE N 1 171 ? 10.819 19.870 64.506 1.00 122.83 ? 171 ILE N N 1 +ATOM 26039 C CA . ILE N 1 171 ? 11.256 21.064 65.207 1.00 120.84 ? 171 ILE N CA 1 +ATOM 26040 C C . ILE N 1 171 ? 10.386 21.252 66.448 1.00 108.35 ? 171 ILE N C 1 +ATOM 26041 O O . ILE N 1 171 ? 9.166 21.225 66.342 1.00 159.65 ? 171 ILE N O 1 +ATOM 26042 C CB . ILE N 1 171 ? 11.149 22.295 64.310 1.00 116.49 ? 171 ILE N CB 1 +ATOM 26043 C CG1 . ILE N 1 171 ? 12.209 22.212 63.214 1.00 112.64 ? 171 ILE N CG1 1 +ATOM 26044 C CG2 . ILE N 1 171 ? 11.303 23.559 65.147 1.00 127.21 ? 171 ILE N CG2 1 +ATOM 26045 C CD1 . ILE N 1 171 ? 11.952 23.158 62.067 1.00 111.93 ? 171 ILE N CD1 1 +ATOM 26046 N N . LEU N 1 172 ? 11.005 21.354 67.618 1.00 99.25 ? 172 LEU N N 1 +ATOM 26047 C CA . LEU N 1 172 ? 10.251 21.407 68.862 1.00 93.38 ? 172 LEU N CA 1 +ATOM 26048 C C . LEU N 1 172 ? 10.027 22.851 69.297 1.00 110.83 ? 172 LEU N C 1 +ATOM 26049 O O . LEU N 1 172 ? 9.197 23.139 70.200 1.00 126.98 ? 172 LEU N O 1 +ATOM 26050 C CB . LEU N 1 172 ? 10.937 20.626 69.994 1.00 77.08 ? 172 LEU N CB 1 +ATOM 26051 C CG . LEU N 1 172 ? 10.634 19.133 70.213 1.00 68.00 ? 172 LEU N CG 1 +ATOM 26052 C CD1 . LEU N 1 172 ? 10.201 18.545 68.894 1.00 70.94 ? 172 LEU N CD1 1 +ATOM 26053 C CD2 . LEU N 1 172 ? 11.697 18.293 70.899 1.00 64.57 ? 172 LEU N CD2 1 +ATOM 26054 N N . SER N 1 173 ? 10.736 23.765 68.645 1.00 89.71 ? 173 SER N N 1 +ATOM 26055 C CA . SER N 1 173 ? 10.562 25.170 68.935 1.00 124.03 ? 173 SER N CA 1 +ATOM 26056 C C . SER N 1 173 ? 11.300 26.007 67.904 1.00 123.12 ? 173 SER N C 1 +ATOM 26057 O O . SER N 1 173 ? 12.483 25.824 67.692 1.00 112.08 ? 173 SER N O 1 +ATOM 26058 C CB . SER N 1 173 ? 11.086 25.494 70.349 1.00 156.70 ? 173 SER N CB 1 +ATOM 26059 O OG . SER N 1 173 ? 11.260 26.897 70.537 1.00 183.80 ? 173 SER N OG 1 +ATOM 26060 N N . SER N 1 174 ? 10.638 27.042 67.392 1.00 150.12 ? 174 SER N N 1 +ATOM 26061 C CA . SER N 1 174 ? 11.318 28.117 66.646 1.00 143.75 ? 174 SER N CA 1 +ATOM 26062 C C . SER N 1 174 ? 11.062 29.483 67.281 1.00 147.14 ? 174 SER N C 1 +ATOM 26063 O O . SER N 1 174 ? 9.949 29.779 67.708 1.00 142.83 ? 174 SER N O 1 +ATOM 26064 C CB . SER N 1 174 ? 10.834 28.151 65.197 1.00 128.82 ? 174 SER N CB 1 +ATOM 26065 O OG . SER N 1 174 ? 11.641 28.986 64.380 1.00 117.58 ? 174 SER N OG 1 +ATOM 26066 N N . VAL N 1 175 ? 12.116 30.290 67.386 1.00 163.50 ? 175 VAL N N 1 +ATOM 26067 C CA . VAL N 1 175 ? 12.012 31.631 67.967 1.00 153.39 ? 175 VAL N CA 1 +ATOM 26068 C C . VAL N 1 175 ? 12.770 32.658 67.136 1.00 156.66 ? 175 VAL N C 1 +ATOM 26069 O O . VAL N 1 175 ? 13.847 32.366 66.595 1.00 266.87 ? 175 VAL N O 1 +ATOM 26070 C CB . VAL N 1 175 ? 12.531 31.679 69.428 1.00 126.56 ? 175 VAL N CB 1 +ATOM 26071 C CG1 . VAL N 1 175 ? 11.689 30.788 70.313 1.00 119.58 ? 175 VAL N CG1 1 +ATOM 26072 C CG2 . VAL N 1 175 ? 13.978 31.241 69.516 1.00 135.57 ? 175 VAL N CG2 1 +ATOM 26073 N N . ASN N 1 176 ? 12.224 33.867 67.075 1.00 117.87 ? 176 ASN N N 1 +ATOM 26074 C CA . ASN N 1 176 ? 12.752 34.916 66.214 1.00 124.83 ? 176 ASN N CA 1 +ATOM 26075 C C . ASN N 1 176 ? 13.023 36.194 66.990 1.00 115.67 ? 176 ASN N C 1 +ATOM 26076 O O . ASN N 1 176 ? 12.125 37.029 67.105 1.00 179.55 ? 176 ASN N O 1 +ATOM 26077 C CB . ASN N 1 176 ? 11.747 35.169 65.075 1.00 141.61 ? 176 ASN N CB 1 +ATOM 26078 C CG . ASN N 1 176 ? 12.130 34.435 63.791 1.00 153.24 ? 176 ASN N CG 1 +ATOM 26079 O OD1 . ASN N 1 176 ? 12.937 33.517 63.866 1.00 150.06 ? 176 ASN N OD1 1 +ATOM 26080 N ND2 . ASN N 1 176 ? 11.503 34.764 62.635 1.00 153.51 ? 176 ASN N ND2 1 +ATOM 26081 N N . THR N 1 177 ? 14.262 36.395 67.445 1.00 89.97 ? 177 THR N N 1 +ATOM 26082 C CA . THR N 1 177 ? 14.604 37.598 68.209 1.00 95.82 ? 177 THR N CA 1 +ATOM 26083 C C . THR N 1 177 ? 15.212 38.701 67.339 1.00 104.79 ? 177 THR N C 1 +ATOM 26084 O O . THR N 1 177 ? 15.673 38.447 66.230 1.00 115.85 ? 177 THR N O 1 +ATOM 26085 C CB . THR N 1 177 ? 15.570 37.288 69.348 1.00 92.69 ? 177 THR N CB 1 +ATOM 26086 O OG1 . THR N 1 177 ? 16.852 36.970 68.808 1.00 119.76 ? 177 THR N OG1 1 +ATOM 26087 C CG2 . THR N 1 177 ? 15.066 36.115 70.176 1.00 97.91 ? 177 THR N CG2 1 +ATOM 26088 N N . SER N 1 178 ? 15.149 39.936 67.832 1.00 110.72 ? 178 SER N N 1 +ATOM 26089 C CA . SER N 1 178 ? 15.599 41.106 67.074 1.00 120.62 ? 178 SER N CA 1 +ATOM 26090 C C . SER N 1 178 ? 16.211 42.151 67.999 1.00 122.25 ? 178 SER N C 1 +ATOM 26091 O O . SER N 1 178 ? 15.851 42.254 69.174 1.00 137.56 ? 178 SER N O 1 +ATOM 26092 C CB . SER N 1 178 ? 14.445 41.736 66.281 1.00 103.83 ? 178 SER N CB 1 +ATOM 26093 O OG . SER N 1 178 ? 14.804 43.032 65.800 1.00 122.70 ? 178 SER N OG 1 +ATOM 26094 N N . LYS N 1 179 ? 17.107 42.960 67.450 1.00 100.53 ? 179 LYS N N 1 +ATOM 26095 C CA . LYS N 1 179 ? 17.818 43.914 68.263 1.00 99.13 ? 179 LYS N CA 1 +ATOM 26096 C C . LYS N 1 179 ? 18.286 45.088 67.414 1.00 101.25 ? 179 LYS N C 1 +ATOM 26097 O O . LYS N 1 179 ? 18.661 44.939 66.249 1.00 86.79 ? 179 LYS N O 1 +ATOM 26098 C CB . LYS N 1 179 ? 18.988 43.207 68.943 1.00 111.75 ? 179 LYS N CB 1 +ATOM 26099 C CG . LYS N 1 179 ? 19.290 43.683 70.356 1.00 112.05 ? 179 LYS N CG 1 +ATOM 26100 C CD . LYS N 1 179 ? 20.365 44.749 70.326 1.00 130.58 ? 179 LYS N CD 1 +ATOM 26101 C CE . LYS N 1 179 ? 20.555 45.348 71.698 1.00 127.18 ? 179 LYS N CE 1 +ATOM 26102 N NZ . LYS N 1 179 ? 21.369 46.588 71.632 1.00 150.20 ? 179 LYS N NZ 1 +ATOM 26103 N N . THR N 1 180 ? 18.288 46.264 68.026 1.00 122.67 ? 180 THR N N 1 +ATOM 26104 C CA . THR N 1 180 ? 18.634 47.492 67.325 1.00 144.11 ? 180 THR N CA 1 +ATOM 26105 C C . THR N 1 180 ? 20.028 48.009 67.733 1.00 154.55 ? 180 THR N C 1 +ATOM 26106 O O . THR N 1 180 ? 20.369 48.076 68.924 1.00 111.22 ? 180 THR N O 1 +ATOM 26107 C CB . THR N 1 180 ? 17.566 48.592 67.533 1.00 134.02 ? 180 THR N CB 1 +ATOM 26108 O OG1 . THR N 1 180 ? 18.158 49.879 67.321 1.00 152.54 ? 180 THR N OG1 1 +ATOM 26109 C CG2 . THR N 1 180 ? 16.966 48.511 68.928 1.00 107.00 ? 180 THR N CG2 1 +ATOM 26110 N N . ILE N 1 181 ? 20.834 48.349 66.725 1.00 155.17 ? 181 ILE N N 1 +ATOM 26111 C CA . ILE N 1 181 ? 22.172 48.888 66.952 1.00 149.66 ? 181 ILE N CA 1 +ATOM 26112 C C . ILE N 1 181 ? 22.156 50.415 66.844 1.00 138.67 ? 181 ILE N C 1 +ATOM 26113 O O . ILE N 1 181 ? 21.886 50.965 65.764 1.00 142.60 ? 181 ILE N O 1 +ATOM 26114 C CB . ILE N 1 181 ? 23.195 48.290 65.950 1.00 134.52 ? 181 ILE N CB 1 +ATOM 26115 C CG1 . ILE N 1 181 ? 23.123 46.763 65.978 1.00 130.36 ? 181 ILE N CG1 1 +ATOM 26116 C CG2 . ILE N 1 181 ? 24.621 48.725 66.285 1.00 139.73 ? 181 ILE N CG2 1 +ATOM 26117 C CD1 . ILE N 1 181 ? 22.750 46.153 64.648 1.00 123.89 ? 181 ILE N CD1 1 +ATOM 26118 N N . LEU N 1 182 ? 22.462 51.086 67.959 1.00 108.24 ? 182 LEU N N 1 +ATOM 26119 C CA . LEU N 1 182 ? 22.478 52.552 68.016 1.00 125.83 ? 182 LEU N CA 1 +ATOM 26120 C C . LEU N 1 182 ? 23.839 53.216 67.694 1.00 137.40 ? 182 LEU N C 1 +ATOM 26121 O O . LEU N 1 182 ? 24.893 52.776 68.161 1.00 131.89 ? 182 LEU N O 1 +ATOM 26122 C CB . LEU N 1 182 ? 22.033 53.007 69.397 1.00 108.06 ? 182 LEU N CB 1 +ATOM 26123 C CG . LEU N 1 182 ? 21.980 54.527 69.608 1.00 99.32 ? 182 LEU N CG 1 +ATOM 26124 C CD1 . LEU N 1 182 ? 20.997 55.238 68.687 1.00 77.92 ? 182 LEU N CD1 1 +ATOM 26125 C CD2 . LEU N 1 182 ? 21.653 54.775 71.071 1.00 107.81 ? 182 LEU N CD2 1 +ATOM 26126 N N . SER N 1 183 ? 23.784 54.321 66.949 1.00 139.80 ? 183 SER N N 1 +ATOM 26127 C CA . SER N 1 183 ? 24.961 55.145 66.672 1.00 137.73 ? 183 SER N CA 1 +ATOM 26128 C C . SER N 1 183 ? 24.593 56.630 66.735 1.00 142.24 ? 183 SER N C 1 +ATOM 26129 O O . SER N 1 183 ? 23.508 57.024 66.297 1.00 120.71 ? 183 SER N O 1 +ATOM 26130 C CB . SER N 1 183 ? 25.527 54.816 65.285 1.00 139.60 ? 183 SER N CB 1 +ATOM 26131 O OG . SER N 1 183 ? 25.432 53.432 65.009 1.00 114.80 ? 183 SER N OG 1 +ATOM 26132 N N . TYR N 1 184 ? 25.486 57.448 67.289 1.00 147.52 ? 184 TYR N N 1 +ATOM 26133 C CA . TYR N 1 184 ? 25.267 58.892 67.329 1.00 128.23 ? 184 TYR N CA 1 +ATOM 26134 C C . TYR N 1 184 ? 26.555 59.718 67.322 1.00 131.30 ? 184 TYR N C 1 +ATOM 26135 O O . TYR N 1 184 ? 27.617 59.277 67.787 1.00 140.89 ? 184 TYR N O 1 +ATOM 26136 C CB . TYR N 1 184 ? 24.361 59.285 68.508 1.00 105.50 ? 184 TYR N CB 1 +ATOM 26137 C CG . TYR N 1 184 ? 24.891 58.892 69.860 1.00 107.43 ? 184 TYR N CG 1 +ATOM 26138 C CD1 . TYR N 1 184 ? 25.765 59.720 70.557 1.00 130.79 ? 184 TYR N CD1 1 +ATOM 26139 C CD2 . TYR N 1 184 ? 24.496 57.707 70.464 1.00 108.77 ? 184 TYR N CD2 1 +ATOM 26140 C CE1 . TYR N 1 184 ? 26.243 59.363 71.807 1.00 141.57 ? 184 TYR N CE1 1 +ATOM 26141 C CE2 . TYR N 1 184 ? 24.967 57.344 71.720 1.00 114.75 ? 184 TYR N CE2 1 +ATOM 26142 C CZ . TYR N 1 184 ? 25.837 58.171 72.386 1.00 125.29 ? 184 TYR N CZ 1 +ATOM 26143 O OH . TYR N 1 184 ? 26.328 57.793 73.608 1.00 114.03 ? 184 TYR N OH 1 +ATOM 26144 N N . GLU N 1 185 ? 26.418 60.949 66.837 1.00 148.15 ? 185 GLU N N 1 +ATOM 26145 C CA . GLU N 1 185 ? 27.523 61.896 66.707 1.00 170.85 ? 185 GLU N CA 1 +ATOM 26146 C C . GLU N 1 185 ? 27.125 63.271 67.223 1.00 162.51 ? 185 GLU N C 1 +ATOM 26147 O O . GLU N 1 185 ? 26.296 63.948 66.628 1.00 139.54 ? 185 GLU N O 1 +ATOM 26148 C CB . GLU N 1 185 ? 27.996 62.049 65.259 1.00 181.07 ? 185 GLU N CB 1 +ATOM 26149 C CG . GLU N 1 185 ? 28.082 60.771 64.454 1.00 179.53 ? 185 GLU N CG 1 +ATOM 26150 C CD . GLU N 1 185 ? 28.750 61.014 63.115 1.00 174.09 ? 185 GLU N CD 1 +ATOM 26151 O OE1 . GLU N 1 185 ? 29.097 62.185 62.815 1.00 162.55 ? 185 GLU N OE1 1 +ATOM 26152 O OE2 . GLU N 1 185 ? 28.956 60.034 62.376 1.00 175.93 ? 185 GLU N OE2 1 +ATOM 26153 N N . VAL N 1 186 ? 27.754 63.681 68.319 1.00 167.52 ? 186 VAL N N 1 +ATOM 26154 C CA . VAL N 1 186 ? 27.548 64.999 68.901 1.00 144.77 ? 186 VAL N CA 1 +ATOM 26155 C C . VAL N 1 186 ? 28.726 65.912 68.551 1.00 132.59 ? 186 VAL N C 1 +ATOM 26156 O O . VAL N 1 186 ? 29.874 65.474 68.572 1.00 121.22 ? 186 VAL N O 1 +ATOM 26157 C CB . VAL N 1 186 ? 27.390 64.900 70.431 1.00 129.24 ? 186 VAL N CB 1 +ATOM 26158 C CG1 . VAL N 1 186 ? 26.979 66.245 71.002 1.00 138.88 ? 186 VAL N CG1 1 +ATOM 26159 C CG2 . VAL N 1 186 ? 26.374 63.824 70.805 1.00 118.00 ? 186 VAL N CG2 1 +ATOM 26160 N N . GLN N 1 187 ? 28.429 67.166 68.216 1.00 135.29 ? 187 GLN N N 1 +ATOM 26161 C CA . GLN N 1 187 ? 29.455 68.098 67.770 1.00 140.60 ? 187 GLN N CA 1 +ATOM 26162 C C . GLN N 1 187 ? 29.112 69.521 68.150 1.00 136.52 ? 187 GLN N C 1 +ATOM 26163 O O . GLN N 1 187 ? 27.971 69.950 68.005 1.00 141.50 ? 187 GLN N O 1 +ATOM 26164 C CB . GLN N 1 187 ? 29.604 68.023 66.247 1.00 148.89 ? 187 GLN N CB 1 +ATOM 26165 C CG . GLN N 1 187 ? 30.537 66.943 65.731 1.00 165.04 ? 187 GLN N CG 1 +ATOM 26166 C CD . GLN N 1 187 ? 30.269 66.607 64.276 1.00 210.38 ? 187 GLN N CD 1 +ATOM 26167 O OE1 . GLN N 1 187 ? 29.973 67.493 63.470 1.00 251.34 ? 187 GLN N OE1 1 +ATOM 26168 N NE2 . GLN N 1 187 ? 30.343 65.317 63.933 1.00 230.82 ? 187 GLN N NE2 1 +ATOM 26169 N N . ALA N 1 188 ? 30.117 70.261 68.602 1.00 156.87 ? 188 ALA N N 1 +ATOM 26170 C CA . ALA N 1 188 ? 29.938 71.677 68.915 1.00 167.88 ? 188 ALA N CA 1 +ATOM 26171 C C . ALA N 1 188 ? 31.165 72.482 68.501 1.00 173.06 ? 188 ALA N C 1 +ATOM 26172 O O . ALA N 1 188 ? 32.287 72.017 68.648 1.00 161.11 ? 188 ALA N O 1 +ATOM 26173 C CB . ALA N 1 188 ? 29.649 71.855 70.398 1.00 147.85 ? 188 ALA N CB 1 +ATOM 26174 N N . GLY N 1 189 ? 30.943 73.675 67.959 1.00 188.69 ? 189 GLY N N 1 +ATOM 26175 C CA . GLY N 1 189 ? 32.037 74.523 67.507 1.00 198.42 ? 189 GLY N CA 1 +ATOM 26176 C C . GLY N 1 189 ? 31.771 76.002 67.716 1.00 216.60 ? 189 GLY N C 1 +ATOM 26177 O O . GLY N 1 189 ? 30.657 76.481 67.502 1.00 238.50 ? 189 GLY N O 1 +ATOM 26178 N N . VAL N 1 190 ? 32.795 76.727 68.151 1.00 221.96 ? 190 VAL N N 1 +ATOM 26179 C CA . VAL N 1 190 ? 32.694 78.171 68.332 1.00 208.36 ? 190 VAL N CA 1 +ATOM 26180 C C . VAL N 1 190 ? 33.610 78.867 67.326 1.00 220.42 ? 190 VAL N C 1 +ATOM 26181 O O . VAL N 1 190 ? 34.763 78.455 67.136 1.00 218.83 ? 190 VAL N O 1 +ATOM 26182 C CB . VAL N 1 190 ? 33.062 78.581 69.774 1.00 189.03 ? 190 VAL N CB 1 +ATOM 26183 C CG1 . VAL N 1 190 ? 32.714 80.038 70.014 1.00 172.48 ? 190 VAL N CG1 1 +ATOM 26184 C CG2 . VAL N 1 190 ? 32.359 77.682 70.789 1.00 188.08 ? 190 VAL N CG2 1 +ATOM 26185 N N . PHE N 1 191 ? 33.097 79.913 66.678 1.00 213.28 ? 191 PHE N N 1 +ATOM 26186 C CA . PHE N 1 191 ? 33.812 80.551 65.566 1.00 195.14 ? 191 PHE N CA 1 +ATOM 26187 C C . PHE N 1 191 ? 33.820 82.075 65.691 1.00 154.43 ? 191 PHE N C 1 +ATOM 26188 O O . PHE N 1 191 ? 32.800 82.679 65.995 1.00 92.55 ? 191 PHE N O 1 +ATOM 26189 C CB . PHE N 1 191 ? 33.162 80.143 64.242 1.00 189.34 ? 191 PHE N CB 1 +ATOM 26190 C CG . PHE N 1 191 ? 34.054 80.298 63.044 1.00 185.32 ? 191 PHE N CG 1 +ATOM 26191 C CD1 . PHE N 1 191 ? 34.339 81.556 62.531 1.00 161.78 ? 191 PHE N CD1 1 +ATOM 26192 C CD2 . PHE N 1 191 ? 34.564 79.181 62.395 1.00 187.10 ? 191 PHE N CD2 1 +ATOM 26193 C CE1 . PHE N 1 191 ? 35.142 81.698 61.415 1.00 159.45 ? 191 PHE N CE1 1 +ATOM 26194 C CE2 . PHE N 1 191 ? 35.375 79.317 61.283 1.00 191.33 ? 191 PHE N CE2 1 +ATOM 26195 C CZ . PHE N 1 191 ? 35.662 80.577 60.790 1.00 186.48 ? 191 PHE N CZ 1 +ATOM 26196 N N . LEU N 1 200 ? 39.339 83.314 65.930 1.00 107.33 ? 200 LEU N N 1 +ATOM 26197 C CA . LEU N 1 200 ? 39.075 82.266 66.917 1.00 132.68 ? 200 LEU N CA 1 +ATOM 26198 C C . LEU N 1 200 ? 38.166 81.181 66.347 1.00 171.92 ? 200 LEU N C 1 +ATOM 26199 O O . LEU N 1 200 ? 36.995 81.440 66.059 1.00 210.37 ? 200 LEU N O 1 +ATOM 26200 C CB . LEU N 1 200 ? 38.415 82.855 68.169 1.00 110.68 ? 200 LEU N CB 1 +ATOM 26201 C CG . LEU N 1 200 ? 37.893 81.807 69.169 1.00 106.23 ? 200 LEU N CG 1 +ATOM 26202 C CD1 . LEU N 1 200 ? 38.875 81.661 70.323 1.00 114.48 ? 200 LEU N CD1 1 +ATOM 26203 C CD2 . LEU N 1 200 ? 36.486 82.104 69.669 1.00 85.45 ? 200 LEU N CD2 1 +ATOM 26204 N N . GLU N 1 201 ? 38.700 79.965 66.223 1.00 183.98 ? 201 GLU N N 1 +ATOM 26205 C CA . GLU N 1 201 ? 37.876 78.767 66.078 1.00 166.04 ? 201 GLU N CA 1 +ATOM 26206 C C . GLU N 1 201 ? 38.152 77.787 67.211 1.00 161.25 ? 201 GLU N C 1 +ATOM 26207 O O . GLU N 1 201 ? 39.273 77.715 67.713 1.00 164.20 ? 201 GLU N O 1 +ATOM 26208 C CB . GLU N 1 201 ? 38.138 78.091 64.736 1.00 160.39 ? 201 GLU N CB 1 +ATOM 26209 C CG . GLU N 1 201 ? 37.019 77.154 64.323 1.00 175.26 ? 201 GLU N CG 1 +ATOM 26210 C CD . GLU N 1 201 ? 37.275 76.476 62.986 1.00 212.22 ? 201 GLU N CD 1 +ATOM 26211 O OE1 . GLU N 1 201 ? 37.573 77.182 61.996 1.00 249.62 ? 201 GLU N OE1 1 +ATOM 26212 O OE2 . GLU N 1 201 ? 37.122 75.238 62.907 1.00 226.43 ? 201 GLU N OE2 1 +ATOM 26213 N N . GLY N 1 202 ? 37.128 77.044 67.617 1.00 146.62 ? 202 GLY N N 1 +ATOM 26214 C CA . GLY N 1 202 ? 37.282 75.970 68.594 1.00 151.59 ? 202 GLY N CA 1 +ATOM 26215 C C . GLY N 1 202 ? 36.207 74.909 68.433 1.00 158.52 ? 202 GLY N C 1 +ATOM 26216 O O . GLY N 1 202 ? 35.021 75.223 68.413 1.00 157.84 ? 202 GLY N O 1 +ATOM 26217 N N . GLU N 1 203 ? 36.617 73.647 68.302 1.00 162.29 ? 203 GLU N N 1 +ATOM 26218 C CA . GLU N 1 203 ? 35.673 72.560 68.036 1.00 150.95 ? 203 GLU N CA 1 +ATOM 26219 C C . GLU N 1 203 ? 35.835 71.352 68.956 1.00 130.60 ? 203 GLU N C 1 +ATOM 26220 O O . GLU N 1 203 ? 36.950 70.909 69.231 1.00 126.25 ? 203 GLU N O 1 +ATOM 26221 C CB . GLU N 1 203 ? 35.793 72.104 66.585 1.00 164.44 ? 203 GLU N CB 1 +ATOM 26222 C CG . GLU N 1 203 ? 35.343 73.165 65.579 1.00 185.08 ? 203 GLU N CG 1 +ATOM 26223 C CD . GLU N 1 203 ? 35.339 72.693 64.128 1.00 198.01 ? 203 GLU N CD 1 +ATOM 26224 O OE1 . GLU N 1 203 ? 35.854 71.585 63.857 1.00 214.65 ? 203 GLU N OE1 1 +ATOM 26225 O OE2 . GLU N 1 203 ? 34.854 73.454 63.254 1.00 183.10 ? 203 GLU N OE2 1 +ATOM 26226 N N . VAL N 1 204 ? 34.699 70.835 69.425 1.00 114.05 ? 204 VAL N N 1 +ATOM 26227 C CA . VAL N 1 204 ? 34.630 69.579 70.176 1.00 96.97 ? 204 VAL N CA 1 +ATOM 26228 C C . VAL N 1 204 ? 33.672 68.627 69.475 1.00 92.79 ? 204 VAL N C 1 +ATOM 26229 O O . VAL N 1 204 ? 32.605 69.031 69.013 1.00 106.26 ? 204 VAL N O 1 +ATOM 26230 C CB . VAL N 1 204 ? 34.162 69.813 71.631 1.00 86.46 ? 204 VAL N CB 1 +ATOM 26231 C CG1 . VAL N 1 204 ? 33.724 68.516 72.307 1.00 74.21 ? 204 VAL N CG1 1 +ATOM 26232 C CG2 . VAL N 1 204 ? 35.273 70.489 72.423 1.00 87.74 ? 204 VAL N CG2 1 +ATOM 26233 N N . GLY N 1 205 ? 34.090 67.372 69.357 1.00 114.62 ? 205 GLY N N 1 +ATOM 26234 C CA . GLY N 1 205 ? 33.268 66.335 68.749 1.00 126.41 ? 205 GLY N CA 1 +ATOM 26235 C C . GLY N 1 205 ? 33.326 65.018 69.514 1.00 123.20 ? 205 GLY N C 1 +ATOM 26236 O O . GLY N 1 205 ? 34.324 64.715 70.172 1.00 102.39 ? 205 GLY N O 1 +ATOM 26237 N N . TYR N 1 206 ? 32.239 64.255 69.451 1.00 124.45 ? 206 TYR N N 1 +ATOM 26238 C CA . TYR N 1 206 ? 32.180 62.928 70.067 1.00 122.66 ? 206 TYR N CA 1 +ATOM 26239 C C . TYR N 1 206 ? 31.268 62.024 69.243 1.00 142.14 ? 206 TYR N C 1 +ATOM 26240 O O . TYR N 1 206 ? 30.229 62.465 68.768 1.00 170.97 ? 206 TYR N O 1 +ATOM 26241 C CB . TYR N 1 206 ? 31.657 63.014 71.513 1.00 100.12 ? 206 TYR N CB 1 +ATOM 26242 C CG . TYR N 1 206 ? 31.502 61.682 72.199 1.00 103.22 ? 206 TYR N CG 1 +ATOM 26243 C CD1 . TYR N 1 206 ? 32.626 60.984 72.675 1.00 104.17 ? 206 TYR N CD1 1 +ATOM 26244 C CD2 . TYR N 1 206 ? 30.250 61.092 72.344 1.00 87.38 ? 206 TYR N CD2 1 +ATOM 26245 C CE1 . TYR N 1 206 ? 32.498 59.738 73.273 1.00 94.55 ? 206 TYR N CE1 1 +ATOM 26246 C CE2 . TYR N 1 206 ? 30.115 59.843 72.928 1.00 106.35 ? 206 TYR N CE2 1 +ATOM 26247 C CZ . TYR N 1 206 ? 31.236 59.171 73.391 1.00 107.24 ? 206 TYR N CZ 1 +ATOM 26248 O OH . TYR N 1 206 ? 31.081 57.916 73.949 1.00 125.78 ? 206 TYR N OH 1 +ATOM 26249 N N . THR N 1 207 ? 31.651 60.758 69.080 1.00 138.19 ? 207 THR N N 1 +ATOM 26250 C CA . THR N 1 207 ? 30.824 59.789 68.352 1.00 109.94 ? 207 THR N CA 1 +ATOM 26251 C C . THR N 1 207 ? 30.794 58.444 69.071 1.00 82.34 ? 207 THR N C 1 +ATOM 26252 O O . THR N 1 207 ? 31.821 57.960 69.554 1.00 52.50 ? 207 THR N O 1 +ATOM 26253 C CB . THR N 1 207 ? 31.334 59.573 66.916 1.00 126.85 ? 207 THR N CB 1 +ATOM 26254 O OG1 . THR N 1 207 ? 32.666 59.052 66.958 1.00 137.35 ? 207 THR N OG1 1 +ATOM 26255 C CG2 . THR N 1 207 ? 31.349 60.877 66.143 1.00 132.15 ? 207 THR N CG2 1 +ATOM 26256 N N . SER N 1 208 ? 29.608 57.843 69.142 1.00 84.68 ? 208 SER N N 1 +ATOM 26257 C CA . SER N 1 208 ? 29.468 56.528 69.769 1.00 98.77 ? 208 SER N CA 1 +ATOM 26258 C C . SER N 1 208 ? 28.650 55.529 68.918 1.00 131.00 ? 208 SER N C 1 +ATOM 26259 O O . SER N 1 208 ? 27.516 55.804 68.547 1.00 129.58 ? 208 SER N O 1 +ATOM 26260 C CB . SER N 1 208 ? 28.854 56.657 71.160 1.00 70.26 ? 208 SER N CB 1 +ATOM 26261 O OG . SER N 1 208 ? 28.616 55.380 71.727 1.00 74.17 ? 208 SER N OG 1 +ATOM 26262 N N . ASN N 1 209 ? 29.243 54.364 68.653 1.00 138.53 ? 209 ASN N N 1 +ATOM 26263 C CA . ASN N 1 209 ? 28.570 53.251 67.997 1.00 108.62 ? 209 ASN N CA 1 +ATOM 26264 C C . ASN N 1 209 ? 28.415 52.092 68.963 1.00 121.70 ? 209 ASN N C 1 +ATOM 26265 O O . ASN N 1 209 ? 29.365 51.714 69.649 1.00 84.49 ? 209 ASN N O 1 +ATOM 26266 C CB . ASN N 1 209 ? 29.379 52.756 66.802 1.00 94.31 ? 209 ASN N CB 1 +ATOM 26267 C CG . ASN N 1 209 ? 29.376 53.727 65.667 1.00 103.76 ? 209 ASN N CG 1 +ATOM 26268 O OD1 . ASN N 1 209 ? 28.450 53.766 64.856 1.00 105.45 ? 209 ASN N OD1 1 +ATOM 26269 N ND2 . ASN N 1 209 ? 30.440 54.511 65.581 1.00 124.34 ? 209 ASN N ND2 1 +ATOM 26270 N N . GLU N 1 210 ? 27.245 51.463 68.939 1.00 150.24 ? 210 GLU N N 1 +ATOM 26271 C CA . GLU N 1 210 ? 27.090 50.153 69.565 1.00 141.37 ? 210 GLU N CA 1 +ATOM 26272 C C . GLU N 1 210 ? 27.888 49.099 68.770 1.00 160.45 ? 210 GLU N C 1 +ATOM 26273 O O . GLU N 1 210 ? 27.945 49.150 67.540 1.00 164.07 ? 210 GLU N O 1 +ATOM 26274 C CB . GLU N 1 210 ? 25.616 49.760 69.616 1.00 125.54 ? 210 GLU N CB 1 +ATOM 26275 C CG . GLU N 1 210 ? 25.156 49.197 70.944 1.00 103.52 ? 210 GLU N CG 1 +ATOM 26276 C CD . GLU N 1 210 ? 23.637 49.225 71.075 1.00 113.61 ? 210 GLU N CD 1 +ATOM 26277 O OE1 . GLU N 1 210 ? 22.941 50.076 70.432 1.00 80.30 ? 210 GLU N OE1 1 +ATOM 26278 O OE2 . GLU N 1 210 ? 23.134 48.376 71.838 1.00 109.35 ? 210 GLU N OE2 1 +ATOM 26279 N N . PRO N 1 211 ? 28.549 48.167 69.473 1.00 147.70 ? 211 PRO N N 1 +ATOM 26280 C CA . PRO N 1 211 ? 29.170 47.050 68.775 1.00 122.82 ? 211 PRO N CA 1 +ATOM 26281 C C . PRO N 1 211 ? 28.137 46.052 68.252 1.00 93.47 ? 211 PRO N C 1 +ATOM 26282 O O . PRO N 1 211 ? 27.261 45.586 69.003 1.00 67.81 ? 211 PRO N O 1 +ATOM 26283 C CB . PRO N 1 211 ? 30.045 46.403 69.860 1.00 132.04 ? 211 PRO N CB 1 +ATOM 26284 C CG . PRO N 1 211 ? 30.200 47.426 70.925 1.00 105.96 ? 211 PRO N CG 1 +ATOM 26285 C CD . PRO N 1 211 ? 28.897 48.170 70.903 1.00 138.83 ? 211 PRO N CD 1 +ATOM 26286 N N . VAL N 1 212 ? 28.205 45.775 66.962 1.00 76.61 ? 212 VAL N N 1 +ATOM 26287 C CA . VAL N 1 212 ? 27.257 44.856 66.334 1.00 93.47 ? 212 VAL N CA 1 +ATOM 26288 C C . VAL N 1 212 ? 27.483 43.497 66.965 1.00 100.86 ? 212 VAL N C 1 +ATOM 26289 O O . VAL N 1 212 ? 26.549 42.713 67.175 1.00 97.02 ? 212 VAL N O 1 +ATOM 26290 C CB . VAL N 1 212 ? 27.480 44.780 64.789 1.00 94.40 ? 212 VAL N CB 1 +ATOM 26291 C CG1 . VAL N 1 212 ? 26.430 43.878 64.130 1.00 68.03 ? 212 VAL N CG1 1 +ATOM 26292 C CG2 . VAL N 1 212 ? 27.470 46.179 64.153 1.00 103.70 ? 212 VAL N CG2 1 +ATOM 26293 N N . MET N 1 213 ? 28.773 43.193 67.126 1.00 108.02 ? 213 MET N N 1 +ATOM 26294 C CA . MET N 1 213 ? 29.291 42.056 67.893 1.00 99.92 ? 213 MET N CA 1 +ATOM 26295 C C . MET N 1 213 ? 28.466 41.780 69.172 1.00 129.27 ? 213 MET N C 1 +ATOM 26296 O O . MET N 1 213 ? 27.993 40.659 69.430 1.00 93.97 ? 213 MET N O 1 +ATOM 26297 C CB . MET N 1 213 ? 30.706 42.477 68.229 1.00 80.17 ? 213 MET N CB 1 +ATOM 26298 C CG . MET N 1 213 ? 31.540 41.503 68.985 1.00 92.58 ? 213 MET N CG 1 +ATOM 26299 S SD . MET N 1 213 ? 33.139 42.316 69.208 1.00 96.33 ? 213 MET N SD 1 +ATOM 26300 C CE . MET N 1 213 ? 32.977 42.534 70.999 1.00 111.19 ? 213 MET N CE 1 +ATOM 26301 N N . LEU N 1 214 ? 28.208 42.851 69.908 1.00 142.28 ? 214 LEU N N 1 +ATOM 26302 C CA . LEU N 1 214 ? 27.672 42.749 71.250 1.00 121.67 ? 214 LEU N CA 1 +ATOM 26303 C C . LEU N 1 214 ? 26.151 42.635 71.178 1.00 125.68 ? 214 LEU N C 1 +ATOM 26304 O O . LEU N 1 214 ? 25.511 42.045 72.053 1.00 145.75 ? 214 LEU N O 1 +ATOM 26305 C CB . LEU N 1 214 ? 28.100 43.980 72.058 1.00 125.68 ? 214 LEU N CB 1 +ATOM 26306 C CG . LEU N 1 214 ? 28.587 43.786 73.492 1.00 122.74 ? 214 LEU N CG 1 +ATOM 26307 C CD1 . LEU N 1 214 ? 29.805 42.884 73.582 1.00 99.89 ? 214 LEU N CD1 1 +ATOM 26308 C CD2 . LEU N 1 214 ? 28.884 45.151 74.109 1.00 133.21 ? 214 LEU N CD2 1 +ATOM 26309 N N . CYS N 1 215 ? 25.568 43.234 70.143 1.00 119.39 ? 215 CYS N N 1 +ATOM 26310 C CA . CYS N 1 215 ? 24.123 43.159 69.922 1.00 128.91 ? 215 CYS N CA 1 +ATOM 26311 C C . CYS N 1 215 ? 23.725 41.748 69.496 1.00 123.25 ? 215 CYS N C 1 +ATOM 26312 O O . CYS N 1 215 ? 22.671 41.212 69.886 1.00 104.14 ? 215 CYS N O 1 +ATOM 26313 C CB . CYS N 1 215 ? 23.704 44.154 68.832 1.00 111.64 ? 215 CYS N CB 1 +ATOM 26314 S SG . CYS N 1 215 ? 23.936 45.871 69.303 1.00 133.76 ? 215 CYS N SG 1 +ATOM 26315 N N . LEU N 1 216 ? 24.542 41.184 68.614 1.00 109.77 ? 216 LEU N N 1 +ATOM 26316 C CA . LEU N 1 216 ? 24.339 39.823 68.190 1.00 83.92 ? 216 LEU N CA 1 +ATOM 26317 C C . LEU N 1 216 ? 24.314 38.955 69.431 1.00 79.39 ? 216 LEU N C 1 +ATOM 26318 O O . LEU N 1 216 ? 23.450 38.087 69.583 1.00 65.81 ? 216 LEU N O 1 +ATOM 26319 C CB . LEU N 1 216 ? 25.450 39.395 67.216 1.00 95.13 ? 216 LEU N CB 1 +ATOM 26320 C CG . LEU N 1 216 ? 25.389 37.937 66.728 1.00 101.87 ? 216 LEU N CG 1 +ATOM 26321 C CD1 . LEU N 1 216 ? 24.063 37.610 66.063 1.00 112.57 ? 216 LEU N CD1 1 +ATOM 26322 C CD2 . LEU N 1 216 ? 26.532 37.636 65.772 1.00 97.70 ? 216 LEU N CD2 1 +ATOM 26323 N N . MET N 1 217 ? 25.311 39.148 70.298 1.00 95.49 ? 217 MET N N 1 +ATOM 26324 C CA . MET N 1 217 ? 25.488 38.266 71.456 1.00 120.27 ? 217 MET N CA 1 +ATOM 26325 C C . MET N 1 217 ? 24.265 38.387 72.357 1.00 130.13 ? 217 MET N C 1 +ATOM 26326 O O . MET N 1 217 ? 23.697 37.375 72.772 1.00 140.49 ? 217 MET N O 1 +ATOM 26327 C CB . MET N 1 217 ? 26.781 38.600 72.222 1.00 121.76 ? 217 MET N CB 1 +ATOM 26328 C CG . MET N 1 217 ? 27.558 37.367 72.686 1.00 106.65 ? 217 MET N CG 1 +ATOM 26329 S SD . MET N 1 217 ? 26.699 36.455 73.978 1.00 99.72 ? 217 MET N SD 1 +ATOM 26330 C CE . MET N 1 217 ? 27.668 34.958 74.105 1.00 124.00 ? 217 MET N CE 1 +ATOM 26331 N N . SER N 1 218 ? 23.832 39.627 72.587 1.00 120.58 ? 218 SER N N 1 +ATOM 26332 C CA . SER N 1 218 ? 22.662 39.912 73.412 1.00 97.53 ? 218 SER N CA 1 +ATOM 26333 C C . SER N 1 218 ? 21.425 39.191 72.882 1.00 102.77 ? 218 SER N C 1 +ATOM 26334 O O . SER N 1 218 ? 20.717 38.499 73.630 1.00 91.88 ? 218 SER N O 1 +ATOM 26335 C CB . SER N 1 218 ? 22.404 41.417 73.442 1.00 81.19 ? 218 SER N CB 1 +ATOM 26336 O OG . SER N 1 218 ? 21.422 41.727 74.415 1.00 123.76 ? 218 SER N OG 1 +ATOM 26337 N N . ALA N 1 219 ? 21.185 39.331 71.582 1.00 112.67 ? 219 ALA N N 1 +ATOM 26338 C CA . ALA N 1 219 ? 19.982 38.775 70.960 1.00 111.47 ? 219 ALA N CA 1 +ATOM 26339 C C . ALA N 1 219 ? 19.964 37.236 70.992 1.00 92.54 ? 219 ALA N C 1 +ATOM 26340 O O . ALA N 1 219 ? 18.921 36.605 71.184 1.00 57.03 ? 219 ALA N O 1 +ATOM 26341 C CB . ALA N 1 219 ? 19.873 39.279 69.537 1.00 115.30 ? 219 ALA N CB 1 +ATOM 26342 N N . ILE N 1 220 ? 21.140 36.636 70.890 1.00 102.10 ? 220 ILE N N 1 +ATOM 26343 C CA . ILE N 1 220 ? 21.247 35.181 70.983 1.00 114.01 ? 220 ILE N CA 1 +ATOM 26344 C C . ILE N 1 220 ? 20.904 34.687 72.390 1.00 112.63 ? 220 ILE N C 1 +ATOM 26345 O O . ILE N 1 220 ? 20.217 33.676 72.554 1.00 105.14 ? 220 ILE N O 1 +ATOM 26346 C CB . ILE N 1 220 ? 22.655 34.689 70.559 1.00 119.18 ? 220 ILE N CB 1 +ATOM 26347 C CG1 . ILE N 1 220 ? 22.847 34.916 69.047 1.00 107.56 ? 220 ILE N CG1 1 +ATOM 26348 C CG2 . ILE N 1 220 ? 22.847 33.213 70.915 1.00 108.25 ? 220 ILE N CG2 1 +ATOM 26349 C CD1 . ILE N 1 220 ? 24.282 34.849 68.580 1.00 91.77 ? 220 ILE N CD1 1 +ATOM 26350 N N . GLU N 1 221 ? 21.382 35.404 73.407 1.00 120.35 ? 221 GLU N N 1 +ATOM 26351 C CA . GLU N 1 221 ? 21.064 35.073 74.814 1.00 112.59 ? 221 GLU N CA 1 +ATOM 26352 C C . GLU N 1 221 ? 19.555 35.111 75.068 1.00 98.76 ? 221 GLU N C 1 +ATOM 26353 O O . GLU N 1 221 ? 18.967 34.127 75.525 1.00 73.75 ? 221 GLU N O 1 +ATOM 26354 C CB . GLU N 1 221 ? 21.758 36.056 75.756 1.00 110.29 ? 221 GLU N CB 1 +ATOM 26355 C CG . GLU N 1 221 ? 23.254 35.833 75.894 1.00 119.74 ? 221 GLU N CG 1 +ATOM 26356 C CD . GLU N 1 221 ? 23.997 37.028 76.485 1.00 120.58 ? 221 GLU N CD 1 +ATOM 26357 O OE1 . GLU N 1 221 ? 23.645 38.201 76.185 1.00 68.50 ? 221 GLU N OE1 1 +ATOM 26358 O OE2 . GLU N 1 221 ? 24.979 36.759 77.216 1.00 154.45 ? 221 GLU N OE2 1 +ATOM 26359 N N . THR N 1 222 ? 18.945 36.227 74.669 1.00 82.59 ? 222 THR N N 1 +ATOM 26360 C CA . THR N 1 222 ? 17.498 36.397 74.690 1.00 75.18 ? 222 THR N CA 1 +ATOM 26361 C C . THR N 1 222 ? 16.770 35.220 74.039 1.00 89.57 ? 222 THR N C 1 +ATOM 26362 O O . THR N 1 222 ? 15.815 34.677 74.608 1.00 86.62 ? 222 THR N O 1 +ATOM 26363 C CB . THR N 1 222 ? 17.097 37.682 73.929 1.00 75.16 ? 222 THR N CB 1 +ATOM 26364 O OG1 . THR N 1 222 ? 17.528 38.832 74.671 1.00 78.43 ? 222 THR N OG1 1 +ATOM 26365 C CG2 . THR N 1 222 ? 15.577 37.731 73.657 1.00 68.74 ? 222 THR N CG2 1 +ATOM 26366 N N . GLY N 1 223 ? 17.207 34.850 72.829 1.00 93.61 ? 223 GLY N N 1 +ATOM 26367 C CA . GLY N 1 223 ? 16.662 33.689 72.124 1.00 92.62 ? 223 GLY N CA 1 +ATOM 26368 C C . GLY N 1 223 ? 16.747 32.398 72.938 1.00 93.64 ? 223 GLY N C 1 +ATOM 26369 O O . GLY N 1 223 ? 15.797 31.594 72.947 1.00 83.10 ? 223 GLY N O 1 +ATOM 26370 N N . VAL N 1 224 ? 17.862 32.213 73.644 1.00 75.19 ? 224 VAL N N 1 +ATOM 26371 C CA . VAL N 1 224 ? 18.049 31.016 74.424 1.00 91.43 ? 224 VAL N CA 1 +ATOM 26372 C C . VAL N 1 224 ? 17.027 30.982 75.550 1.00 119.13 ? 224 VAL N C 1 +ATOM 26373 O O . VAL N 1 224 ? 16.438 29.932 75.842 1.00 133.37 ? 224 VAL N O 1 +ATOM 26374 C CB . VAL N 1 224 ? 19.464 30.931 75.007 1.00 98.48 ? 224 VAL N CB 1 +ATOM 26375 C CG1 . VAL N 1 224 ? 19.565 29.762 75.980 1.00 111.98 ? 224 VAL N CG1 1 +ATOM 26376 C CG2 . VAL N 1 224 ? 20.488 30.777 73.894 1.00 104.44 ? 224 VAL N CG2 1 +ATOM 26377 N N . ILE N 1 225 ? 16.800 32.133 76.174 1.00 147.48 ? 225 ILE N N 1 +ATOM 26378 C CA . ILE N 1 225 ? 15.808 32.219 77.251 1.00 156.76 ? 225 ILE N CA 1 +ATOM 26379 C C . ILE N 1 225 ? 14.418 31.854 76.738 1.00 153.97 ? 225 ILE N C 1 +ATOM 26380 O O . ILE N 1 225 ? 13.773 30.973 77.307 1.00 106.02 ? 225 ILE N O 1 +ATOM 26381 C CB . ILE N 1 225 ? 15.768 33.616 77.901 1.00 149.01 ? 225 ILE N CB 1 +ATOM 26382 C CG1 . ILE N 1 225 ? 17.066 33.879 78.666 1.00 161.21 ? 225 ILE N CG1 1 +ATOM 26383 C CG2 . ILE N 1 225 ? 14.596 33.718 78.862 1.00 126.42 ? 225 ILE N CG2 1 +ATOM 26384 C CD1 . ILE N 1 225 ? 17.308 35.341 78.970 1.00 170.40 ? 225 ILE N CD1 1 +ATOM 26385 N N . PHE N 1 226 ? 13.981 32.504 75.654 1.00 155.56 ? 226 PHE N N 1 +ATOM 26386 C CA . PHE N 1 226 ? 12.682 32.200 75.038 1.00 150.26 ? 226 PHE N CA 1 +ATOM 26387 C C . PHE N 1 226 ? 12.551 30.709 74.682 1.00 163.16 ? 226 PHE N C 1 +ATOM 26388 O O . PHE N 1 226 ? 11.458 30.139 74.758 1.00 191.53 ? 226 PHE N O 1 +ATOM 26389 C CB . PHE N 1 226 ? 12.443 33.048 73.781 1.00 137.71 ? 226 PHE N CB 1 +ATOM 26390 C CG . PHE N 1 226 ? 11.996 34.456 74.060 1.00 109.13 ? 226 PHE N CG 1 +ATOM 26391 C CD1 . PHE N 1 226 ? 10.808 34.693 74.710 1.00 133.71 ? 226 PHE N CD1 1 +ATOM 26392 C CD2 . PHE N 1 226 ? 12.717 35.544 73.571 1.00 99.18 ? 226 PHE N CD2 1 +ATOM 26393 C CE1 . PHE N 1 226 ? 10.379 35.995 74.933 1.00 165.81 ? 226 PHE N CE1 1 +ATOM 26394 C CE2 . PHE N 1 226 ? 12.270 36.842 73.740 1.00 97.20 ? 226 PHE N CE2 1 +ATOM 26395 C CZ . PHE N 1 226 ? 11.113 37.071 74.445 1.00 125.09 ? 226 PHE N CZ 1 +ATOM 26396 N N . LEU N 1 227 ? 13.653 30.085 74.274 1.00 128.94 ? 227 LEU N N 1 +ATOM 26397 C CA . LEU N 1 227 ? 13.653 28.667 73.976 1.00 120.13 ? 227 LEU N CA 1 +ATOM 26398 C C . LEU N 1 227 ? 13.400 27.845 75.234 1.00 140.28 ? 227 LEU N C 1 +ATOM 26399 O O . LEU N 1 227 ? 12.633 26.877 75.203 1.00 152.22 ? 227 LEU N O 1 +ATOM 26400 C CB . LEU N 1 227 ? 14.985 28.280 73.338 1.00 113.24 ? 227 LEU N CB 1 +ATOM 26401 C CG . LEU N 1 227 ? 15.147 28.650 71.862 1.00 117.11 ? 227 LEU N CG 1 +ATOM 26402 C CD1 . LEU N 1 227 ? 16.553 28.530 71.317 1.00 109.75 ? 227 LEU N CD1 1 +ATOM 26403 C CD2 . LEU N 1 227 ? 14.210 27.842 70.986 1.00 140.13 ? 227 LEU N CD2 1 +ATOM 26404 N N . ILE N 1 228 ? 14.079 28.193 76.326 1.00 137.14 ? 228 ILE N N 1 +ATOM 26405 C CA . ILE N 1 228 ? 13.953 27.434 77.570 1.00 131.65 ? 228 ILE N CA 1 +ATOM 26406 C C . ILE N 1 228 ? 12.527 27.570 78.080 1.00 127.77 ? 228 ILE N C 1 +ATOM 26407 O O . ILE N 1 228 ? 11.892 26.586 78.465 1.00 105.08 ? 228 ILE N O 1 +ATOM 26408 C CB . ILE N 1 228 ? 14.938 27.909 78.663 1.00 117.10 ? 228 ILE N CB 1 +ATOM 26409 C CG1 . ILE N 1 228 ? 16.381 27.650 78.241 1.00 140.53 ? 228 ILE N CG1 1 +ATOM 26410 C CG2 . ILE N 1 228 ? 14.685 27.166 79.962 1.00 92.10 ? 228 ILE N CG2 1 +ATOM 26411 C CD1 . ILE N 1 228 ? 17.413 28.401 79.058 1.00 161.49 ? 228 ILE N CD1 1 +ATOM 26412 N N . ASN N 1 229 ? 12.037 28.802 78.102 1.00 137.87 ? 229 ASN N N 1 +ATOM 26413 C CA . ASN N 1 229 ? 10.698 29.082 78.610 1.00 144.11 ? 229 ASN N CA 1 +ATOM 26414 C C . ASN N 1 229 ? 9.670 28.323 77.787 1.00 135.62 ? 229 ASN N C 1 +ATOM 26415 O O . ASN N 1 229 ? 8.735 27.729 78.328 1.00 105.74 ? 229 ASN N O 1 +ATOM 26416 C CB . ASN N 1 229 ? 10.429 30.592 78.568 1.00 148.08 ? 229 ASN N CB 1 +ATOM 26417 C CG . ASN N 1 229 ? 9.235 30.997 79.393 1.00 142.81 ? 229 ASN N CG 1 +ATOM 26418 O OD1 . ASN N 1 229 ? 8.856 30.314 80.356 1.00 148.91 ? 229 ASN N OD1 1 +ATOM 26419 N ND2 . ASN N 1 229 ? 8.672 32.155 79.072 1.00 137.37 ? 229 ASN N ND2 1 +ATOM 26420 N N . ASP N 1 230 ? 9.863 28.335 76.470 1.00 148.32 ? 230 ASP N N 1 +ATOM 26421 C CA . ASP N 1 230 ? 8.960 27.652 75.544 1.00 155.09 ? 230 ASP N CA 1 +ATOM 26422 C C . ASP N 1 230 ? 8.978 26.153 75.803 1.00 125.58 ? 230 ASP N C 1 +ATOM 26423 O O . ASP N 1 230 ? 7.923 25.501 75.813 1.00 125.88 ? 230 ASP N O 1 +ATOM 26424 C CB . ASP N 1 230 ? 9.363 27.932 74.093 1.00 172.05 ? 230 ASP N CB 1 +ATOM 26425 C CG . ASP N 1 230 ? 8.385 27.341 73.088 1.00 190.33 ? 230 ASP N CG 1 +ATOM 26426 O OD1 . ASP N 1 230 ? 7.271 27.892 72.966 1.00 258.49 ? 230 ASP N OD1 1 +ATOM 26427 O OD2 . ASP N 1 230 ? 8.709 26.333 72.445 1.00 144.53 ? 230 ASP N OD2 1 +ATOM 26428 N N . GLY N 1 231 ? 10.165 25.627 76.072 1.00 99.82 ? 231 GLY N N 1 +ATOM 26429 C CA . GLY N 1 231 ? 10.312 24.207 76.358 1.00 128.62 ? 231 GLY N CA 1 +ATOM 26430 C C . GLY N 1 231 ? 9.702 23.801 77.691 1.00 139.07 ? 231 GLY N C 1 +ATOM 26431 O O . GLY N 1 231 ? 9.115 22.708 77.812 1.00 137.06 ? 231 GLY N O 1 +ATOM 26432 N N . ILE N 1 232 ? 9.756 24.714 78.662 1.00 146.98 ? 232 ILE N N 1 +ATOM 26433 C CA . ILE N 1 232 ? 9.073 24.518 79.949 1.00 143.33 ? 232 ILE N CA 1 +ATOM 26434 C C . ILE N 1 232 ? 7.556 24.399 79.764 1.00 156.25 ? 232 ILE N C 1 +ATOM 26435 O O . ILE N 1 232 ? 6.951 23.435 80.234 1.00 129.53 ? 232 ILE N O 1 +ATOM 26436 C CB . ILE N 1 232 ? 9.376 25.666 80.934 1.00 134.88 ? 232 ILE N CB 1 +ATOM 26437 C CG1 . ILE N 1 232 ? 10.819 25.552 81.424 1.00 131.81 ? 232 ILE N CG1 1 +ATOM 26438 C CG2 . ILE N 1 232 ? 8.403 25.650 82.112 1.00 142.63 ? 232 ILE N CG2 1 +ATOM 26439 C CD1 . ILE N 1 232 ? 11.355 26.822 82.048 1.00 132.42 ? 232 ILE N CD1 1 +ATOM 26440 N N . ASP N 1 233 ? 6.966 25.356 79.042 1.00 182.26 ? 233 ASP N N 1 +ATOM 26441 C CA . ASP N 1 233 ? 5.528 25.336 78.700 1.00 154.88 ? 233 ASP N CA 1 +ATOM 26442 C C . ASP N 1 233 ? 5.117 24.050 77.978 1.00 138.81 ? 233 ASP N C 1 +ATOM 26443 O O . ASP N 1 233 ? 4.172 23.387 78.384 1.00 169.69 ? 233 ASP N O 1 +ATOM 26444 C CB . ASP N 1 233 ? 5.158 26.529 77.809 1.00 152.98 ? 233 ASP N CB 1 +ATOM 26445 C CG . ASP N 1 233 ? 5.323 27.869 78.514 1.00 169.89 ? 233 ASP N CG 1 +ATOM 26446 O OD1 . ASP N 1 233 ? 5.926 27.911 79.620 1.00 167.60 ? 233 ASP N OD1 1 +ATOM 26447 O OD2 . ASP N 1 233 ? 4.900 28.894 77.933 1.00 141.68 ? 233 ASP N OD2 1 +ATOM 26448 N N . ARG N 1 234 ? 5.875 23.664 76.954 1.00 114.98 ? 234 ARG N N 1 +ATOM 26449 C CA . ARG N 1 234 ? 5.519 22.510 76.124 1.00 101.58 ? 234 ARG N CA 1 +ATOM 26450 C C . ARG N 1 234 ? 5.880 21.140 76.718 1.00 122.59 ? 234 ARG N C 1 +ATOM 26451 O O . ARG N 1 234 ? 5.639 20.105 76.099 1.00 126.62 ? 234 ARG N O 1 +ATOM 26452 C CB . ARG N 1 234 ? 6.144 22.673 74.746 1.00 90.28 ? 234 ARG N CB 1 +ATOM 26453 C CG . ARG N 1 234 ? 5.456 23.748 73.946 1.00 96.41 ? 234 ARG N CG 1 +ATOM 26454 C CD . ARG N 1 234 ? 6.321 24.296 72.829 1.00 101.13 ? 234 ARG N CD 1 +ATOM 26455 N NE . ARG N 1 234 ? 5.607 25.367 72.153 1.00 102.42 ? 234 ARG N NE 1 +ATOM 26456 C CZ . ARG N 1 234 ? 5.245 25.343 70.879 1.00 108.77 ? 234 ARG N CZ 1 +ATOM 26457 N NH1 . ARG N 1 234 ? 5.623 24.341 70.099 1.00 126.01 ? 234 ARG N NH1 1 +ATOM 26458 N NH2 . ARG N 1 234 ? 4.576 26.367 70.365 1.00 109.78 ? 234 ARG N NH2 1 +ATOM 26459 N N . GLY N 1 235 ? 6.517 21.136 77.886 1.00 140.54 ? 235 GLY N N 1 +ATOM 26460 C CA . GLY N 1 235 ? 6.883 19.892 78.558 1.00 144.98 ? 235 GLY N CA 1 +ATOM 26461 C C . GLY N 1 235 ? 8.082 19.174 77.953 1.00 156.11 ? 235 GLY N C 1 +ATOM 26462 O O . GLY N 1 235 ? 8.139 17.941 77.974 1.00 161.53 ? 235 GLY N O 1 +ATOM 26463 N N . LEU N 1 236 ? 9.038 19.929 77.403 1.00 155.78 ? 236 LEU N N 1 +ATOM 26464 C CA . LEU N 1 236 ? 10.325 19.337 77.005 1.00 153.83 ? 236 LEU N CA 1 +ATOM 26465 C C . LEU N 1 236 ? 11.134 19.037 78.263 1.00 158.63 ? 236 LEU N C 1 +ATOM 26466 O O . LEU N 1 236 ? 11.676 17.943 78.423 1.00 148.08 ? 236 LEU N O 1 +ATOM 26467 C CB . LEU N 1 236 ? 11.129 20.262 76.076 1.00 137.30 ? 236 LEU N CB 1 +ATOM 26468 C CG . LEU N 1 236 ? 10.797 20.223 74.578 1.00 120.76 ? 236 LEU N CG 1 +ATOM 26469 C CD1 . LEU N 1 236 ? 9.544 21.029 74.289 1.00 140.75 ? 236 LEU N CD1 1 +ATOM 26470 C CD2 . LEU N 1 236 ? 11.961 20.785 73.778 1.00 130.63 ? 236 LEU N CD2 1 +ATOM 26471 N N . TRP N 1 237 ? 11.208 20.020 79.154 1.00 161.97 ? 237 TRP N N 1 +ATOM 26472 C CA . TRP N 1 237 ? 11.991 19.893 80.383 1.00 163.68 ? 237 TRP N CA 1 +ATOM 26473 C C . TRP N 1 237 ? 11.238 20.520 81.556 1.00 173.15 ? 237 TRP N C 1 +ATOM 26474 O O . TRP N 1 237 ? 10.289 21.285 81.352 1.00 165.36 ? 237 TRP N O 1 +ATOM 26475 C CB . TRP N 1 237 ? 13.372 20.532 80.198 1.00 149.21 ? 237 TRP N CB 1 +ATOM 26476 C CG . TRP N 1 237 ? 13.349 21.718 79.283 1.00 161.39 ? 237 TRP N CG 1 +ATOM 26477 C CD1 . TRP N 1 237 ? 12.754 22.916 79.518 1.00 168.01 ? 237 TRP N CD1 1 +ATOM 26478 C CD2 . TRP N 1 237 ? 13.932 21.809 77.975 1.00 172.60 ? 237 TRP N CD2 1 +ATOM 26479 N NE1 . TRP N 1 237 ? 12.931 23.752 78.445 1.00 174.08 ? 237 TRP N NE1 1 +ATOM 26480 C CE2 . TRP N 1 237 ? 13.668 23.102 77.491 1.00 156.80 ? 237 TRP N CE2 1 +ATOM 26481 C CE3 . TRP N 1 237 ? 14.658 20.924 77.170 1.00 181.55 ? 237 TRP N CE3 1 +ATOM 26482 C CZ2 . TRP N 1 237 ? 14.109 23.538 76.242 1.00 137.44 ? 237 TRP N CZ2 1 +ATOM 26483 C CZ3 . TRP N 1 237 ? 15.091 21.362 75.921 1.00 146.40 ? 237 TRP N CZ3 1 +ATOM 26484 C CH2 . TRP N 1 237 ? 14.799 22.650 75.468 1.00 119.64 ? 237 TRP N CH2 1 +ATOM 26485 N N . ASP N 1 238 ? 11.679 20.209 82.774 1.00 187.39 ? 238 ASP N N 1 +ATOM 26486 C CA . ASP N 1 238 ? 10.964 20.618 83.987 1.00 181.28 ? 238 ASP N CA 1 +ATOM 26487 C C . ASP N 1 238 ? 11.855 21.307 85.025 1.00 161.35 ? 238 ASP N C 1 +ATOM 26488 O O . ASP N 1 238 ? 13.049 21.002 85.147 1.00 135.98 ? 238 ASP N O 1 +ATOM 26489 C CB . ASP N 1 238 ? 10.286 19.418 84.636 1.00 172.90 ? 238 ASP N CB 1 +ATOM 26490 C CG . ASP N 1 238 ? 9.350 18.698 83.691 1.00 178.29 ? 238 ASP N CG 1 +ATOM 26491 O OD1 . ASP N 1 238 ? 9.848 17.915 82.862 1.00 176.48 ? 238 ASP N OD1 1 +ATOM 26492 O OD2 . ASP N 1 238 ? 8.121 18.909 83.774 1.00 183.77 ? 238 ASP N OD2 1 +ATOM 26493 N N . LEU N 1 239 ? 11.257 22.240 85.768 1.00 134.95 ? 239 LEU N N 1 +ATOM 26494 C CA . LEU N 1 239 ? 11.971 23.008 86.779 1.00 132.46 ? 239 LEU N CA 1 +ATOM 26495 C C . LEU N 1 239 ? 12.196 22.157 88.014 1.00 136.15 ? 239 LEU N C 1 +ATOM 26496 O O . LEU N 1 239 ? 11.354 21.334 88.381 1.00 155.09 ? 239 LEU N O 1 +ATOM 26497 C CB . LEU N 1 239 ? 11.187 24.269 87.165 1.00 134.03 ? 239 LEU N CB 1 +ATOM 26498 C CG . LEU N 1 239 ? 11.194 25.477 86.229 1.00 149.14 ? 239 LEU N CG 1 +ATOM 26499 C CD1 . LEU N 1 239 ? 10.453 26.650 86.852 1.00 155.19 ? 239 LEU N CD1 1 +ATOM 26500 C CD2 . LEU N 1 239 ? 12.614 25.889 85.899 1.00 171.38 ? 239 LEU N CD2 1 +ATOM 26501 N N . GLN N 1 240 ? 13.337 22.372 88.659 1.00 143.90 ? 240 GLN N N 1 +ATOM 26502 C CA . GLN N 1 240 ? 13.598 21.791 89.972 1.00 158.81 ? 240 GLN N CA 1 +ATOM 26503 C C . GLN N 1 240 ? 12.472 22.156 90.943 1.00 159.88 ? 240 GLN N C 1 +ATOM 26504 O O . GLN N 1 240 ? 11.830 21.279 91.530 1.00 120.04 ? 240 GLN N O 1 +ATOM 26505 C CB . GLN N 1 240 ? 14.951 22.285 90.513 1.00 164.93 ? 240 GLN N CB 1 +ATOM 26506 C CG . GLN N 1 240 ? 15.403 21.579 91.787 1.00 171.31 ? 240 GLN N CG 1 +ATOM 26507 C CD . GLN N 1 240 ? 15.689 20.102 91.562 1.00 167.70 ? 240 GLN N CD 1 +ATOM 26508 O OE1 . GLN N 1 240 ? 16.750 19.736 91.054 1.00 156.70 ? 240 GLN N OE1 1 +ATOM 26509 N NE2 . GLN N 1 240 ? 14.719 19.249 91.893 1.00 163.44 ? 240 GLN N NE2 1 +ATOM 26510 N N . ASN N 1 241 ? 12.250 23.458 91.093 1.00 179.75 ? 241 ASN N N 1 +ATOM 26511 C CA . ASN N 1 241 ? 11.207 23.988 91.964 1.00 167.17 ? 241 ASN N CA 1 +ATOM 26512 C C . ASN N 1 241 ? 10.025 24.480 91.148 1.00 162.21 ? 241 ASN N C 1 +ATOM 26513 O O . ASN N 1 241 ? 10.114 25.517 90.475 1.00 134.73 ? 241 ASN N O 1 +ATOM 26514 C CB . ASN N 1 241 ? 11.757 25.149 92.789 1.00 167.80 ? 241 ASN N CB 1 +ATOM 26515 C CG . ASN N 1 241 ? 12.111 24.741 94.199 1.00 166.77 ? 241 ASN N CG 1 +ATOM 26516 O OD1 . ASN N 1 241 ? 11.353 25.013 95.128 1.00 164.09 ? 241 ASN N OD1 1 +ATOM 26517 N ND2 . ASN N 1 241 ? 13.247 24.062 94.367 1.00 156.55 ? 241 ASN N ND2 1 +ATOM 26518 N N . LYS N 1 242 ? 8.907 23.764 91.248 1.00 153.33 ? 242 LYS N N 1 +ATOM 26519 C CA . LYS N 1 242 ? 7.694 24.137 90.519 1.00 140.30 ? 242 LYS N CA 1 +ATOM 26520 C C . LYS N 1 242 ? 7.171 25.475 91.035 1.00 144.22 ? 242 LYS N C 1 +ATOM 26521 O O . LYS N 1 242 ? 6.530 26.233 90.300 1.00 100.89 ? 242 LYS N O 1 +ATOM 26522 C CB . LYS N 1 242 ? 6.633 23.045 90.651 1.00 134.51 ? 242 LYS N CB 1 +ATOM 26523 C CG . LYS N 1 242 ? 7.154 21.645 90.358 1.00 148.30 ? 242 LYS N CG 1 +ATOM 26524 C CD . LYS N 1 242 ? 6.332 20.942 89.291 1.00 174.08 ? 242 LYS N CD 1 +ATOM 26525 C CE . LYS N 1 242 ? 7.230 20.284 88.248 1.00 188.71 ? 242 LYS N CE 1 +ATOM 26526 N NZ . LYS N 1 242 ? 6.467 19.454 87.275 1.00 194.63 ? 242 LYS N NZ 1 +ATOM 26527 N N . ALA N 1 243 ? 7.513 25.765 92.293 1.00 174.98 ? 243 ALA N N 1 +ATOM 26528 C CA . ALA N 1 243 ? 7.234 27.052 92.930 1.00 187.24 ? 243 ALA N CA 1 +ATOM 26529 C C . ALA N 1 243 ? 7.930 28.204 92.216 1.00 185.54 ? 243 ALA N C 1 +ATOM 26530 O O . ALA N 1 243 ? 7.553 29.366 92.404 1.00 188.07 ? 243 ALA N O 1 +ATOM 26531 C CB . ALA N 1 243 ? 7.664 27.014 94.396 1.00 205.01 ? 243 ALA N CB 1 +ATOM 26532 N N . GLU N 1 244 ? 8.970 27.896 91.439 1.00 181.27 ? 244 GLU N N 1 +ATOM 26533 C CA . GLU N 1 244 ? 9.736 28.944 90.774 1.00 174.25 ? 244 GLU N CA 1 +ATOM 26534 C C . GLU N 1 244 ? 9.207 29.248 89.381 1.00 150.40 ? 244 GLU N C 1 +ATOM 26535 O O . GLU N 1 244 ? 9.877 29.928 88.620 1.00 121.01 ? 244 GLU N O 1 +ATOM 26536 C CB . GLU N 1 244 ? 11.225 28.581 90.718 1.00 168.65 ? 244 GLU N CB 1 +ATOM 26537 C CG . GLU N 1 244 ? 11.939 28.699 92.055 1.00 170.52 ? 244 GLU N CG 1 +ATOM 26538 C CD . GLU N 1 244 ? 13.448 28.596 91.930 1.00 161.56 ? 244 GLU N CD 1 +ATOM 26539 O OE1 . GLU N 1 244 ? 13.963 27.469 91.755 1.00 140.19 ? 244 GLU N OE1 1 +ATOM 26540 O OE2 . GLU N 1 244 ? 14.123 29.647 92.013 1.00 160.47 ? 244 GLU N OE2 1 +ATOM 26541 N N . ARG N 1 245 ? 8.034 28.709 89.039 1.00 140.33 ? 245 ARG N N 1 +ATOM 26542 C CA . ARG N 1 245 ? 7.403 29.014 87.753 1.00 137.65 ? 245 ARG N CA 1 +ATOM 26543 C C . ARG N 1 245 ? 7.167 30.511 87.563 1.00 140.02 ? 245 ARG N C 1 +ATOM 26544 O O . ARG N 1 245 ? 7.291 31.016 86.447 1.00 96.61 ? 245 ARG N O 1 +ATOM 26545 C CB . ARG N 1 245 ? 6.080 28.288 87.583 1.00 135.30 ? 245 ARG N CB 1 +ATOM 26546 C CG . ARG N 1 245 ? 5.480 28.452 86.184 1.00 153.39 ? 245 ARG N CG 1 +ATOM 26547 C CD . ARG N 1 245 ? 4.188 27.638 85.985 1.00 171.52 ? 245 ARG N CD 1 +ATOM 26548 N NE . ARG N 1 245 ? 4.446 26.365 85.307 1.00 180.84 ? 245 ARG N NE 1 +ATOM 26549 C CZ . ARG N 1 245 ? 4.766 26.243 84.020 1.00 171.61 ? 245 ARG N CZ 1 +ATOM 26550 N NH1 . ARG N 1 245 ? 4.893 27.313 83.253 1.00 158.94 ? 245 ARG N NH1 1 +ATOM 26551 N NH2 . ARG N 1 245 ? 4.984 25.043 83.493 1.00 169.89 ? 245 ARG N NH2 1 +ATOM 26552 N N . GLN N 1 246 ? 6.833 31.215 88.645 1.00 150.68 ? 246 GLN N N 1 +ATOM 26553 C CA . GLN N 1 246 ? 6.517 32.644 88.554 1.00 143.71 ? 246 GLN N CA 1 +ATOM 26554 C C . GLN N 1 246 ? 7.749 33.502 88.837 1.00 127.25 ? 246 GLN N C 1 +ATOM 26555 O O . GLN N 1 246 ? 7.626 34.673 89.179 1.00 167.06 ? 246 GLN N O 1 +ATOM 26556 C CB . GLN N 1 246 ? 5.375 33.024 89.507 1.00 138.80 ? 246 GLN N CB 1 +ATOM 26557 C CG . GLN N 1 246 ? 4.010 32.498 89.105 1.00 125.50 ? 246 GLN N CG 1 +ATOM 26558 C CD . GLN N 1 246 ? 3.863 31.016 89.390 1.00 156.96 ? 246 GLN N CD 1 +ATOM 26559 O OE1 . GLN N 1 246 ? 4.235 30.536 90.471 1.00 198.20 ? 246 GLN N OE1 1 +ATOM 26560 N NE2 . GLN N 1 246 ? 3.299 30.282 88.436 1.00 155.11 ? 246 GLN N NE2 1 +ATOM 26561 N N . ASN N 1 247 ? 8.928 32.911 88.688 1.00 104.55 ? 247 ASN N N 1 +ATOM 26562 C CA . ASN N 1 247 ? 10.177 33.662 88.623 1.00 133.30 ? 247 ASN N CA 1 +ATOM 26563 C C . ASN N 1 247 ? 10.046 34.970 87.826 1.00 144.96 ? 247 ASN N C 1 +ATOM 26564 O O . ASN N 1 247 ? 9.446 34.986 86.745 1.00 176.61 ? 247 ASN N O 1 +ATOM 26565 C CB . ASN N 1 247 ? 11.259 32.793 87.972 1.00 148.23 ? 247 ASN N CB 1 +ATOM 26566 C CG . ASN N 1 247 ? 12.650 33.162 88.420 1.00 148.70 ? 247 ASN N CG 1 +ATOM 26567 O OD1 . ASN N 1 247 ? 13.447 33.719 87.648 1.00 139.45 ? 247 ASN N OD1 1 +ATOM 26568 N ND2 . ASN N 1 247 ? 12.961 32.842 89.672 1.00 131.04 ? 247 ASN N ND2 1 +ATOM 26569 N N . ASP N 1 248 ? 10.645 36.049 88.335 1.00 149.70 ? 248 ASP N N 1 +ATOM 26570 C CA . ASP N 1 248 ? 10.556 37.378 87.695 1.00 152.00 ? 248 ASP N CA 1 +ATOM 26571 C C . ASP N 1 248 ? 10.957 37.324 86.220 1.00 166.85 ? 248 ASP N C 1 +ATOM 26572 O O . ASP N 1 248 ? 10.289 37.896 85.345 1.00 195.20 ? 248 ASP N O 1 +ATOM 26573 C CB . ASP N 1 248 ? 11.465 38.393 88.409 1.00 164.02 ? 248 ASP N CB 1 +ATOM 26574 C CG . ASP N 1 248 ? 10.949 38.792 89.782 1.00 183.17 ? 248 ASP N CG 1 +ATOM 26575 O OD1 . ASP N 1 248 ? 9.723 38.929 89.953 1.00 175.87 ? 248 ASP N OD1 1 +ATOM 26576 O OD2 . ASP N 1 248 ? 11.784 38.969 90.693 1.00 194.30 ? 248 ASP N OD2 1 +ATOM 26577 N N . ILE N 1 249 ? 12.079 36.661 85.960 1.00 171.92 ? 249 ILE N N 1 +ATOM 26578 C CA . ILE N 1 249 ? 12.647 36.594 84.623 1.00 162.43 ? 249 ILE N CA 1 +ATOM 26579 C C . ILE N 1 249 ? 11.715 35.789 83.712 1.00 143.96 ? 249 ILE N C 1 +ATOM 26580 O O . ILE N 1 249 ? 11.349 36.239 82.616 1.00 146.50 ? 249 ILE N O 1 +ATOM 26581 C CB . ILE N 1 249 ? 14.053 35.956 84.660 1.00 162.49 ? 249 ILE N CB 1 +ATOM 26582 C CG1 . ILE N 1 249 ? 15.017 36.829 85.482 1.00 150.41 ? 249 ILE N CG1 1 +ATOM 26583 C CG2 . ILE N 1 249 ? 14.595 35.790 83.252 1.00 178.11 ? 249 ILE N CG2 1 +ATOM 26584 C CD1 . ILE N 1 249 ? 16.240 36.091 85.986 1.00 145.03 ? 249 ILE N CD1 1 +ATOM 26585 N N . LEU N 1 250 ? 11.311 34.612 84.185 1.00 112.77 ? 250 LEU N N 1 +ATOM 26586 C CA . LEU N 1 250 ? 10.455 33.721 83.398 1.00 118.89 ? 250 LEU N CA 1 +ATOM 26587 C C . LEU N 1 250 ? 9.119 34.360 83.019 1.00 144.25 ? 250 LEU N C 1 +ATOM 26588 O O . LEU N 1 250 ? 8.617 34.149 81.915 1.00 138.72 ? 250 LEU N O 1 +ATOM 26589 C CB . LEU N 1 250 ? 10.207 32.414 84.150 1.00 106.76 ? 250 LEU N CB 1 +ATOM 26590 C CG . LEU N 1 250 ? 11.347 31.391 84.077 1.00 118.45 ? 250 LEU N CG 1 +ATOM 26591 C CD1 . LEU N 1 250 ? 11.170 30.254 85.070 1.00 103.92 ? 250 LEU N CD1 1 +ATOM 26592 C CD2 . LEU N 1 250 ? 11.452 30.833 82.667 1.00 131.33 ? 250 LEU N CD2 1 +ATOM 26593 N N . VAL N 1 251 ? 8.543 35.133 83.940 1.00 182.02 ? 251 VAL N N 1 +ATOM 26594 C CA . VAL N 1 251 ? 7.270 35.818 83.674 1.00 172.02 ? 251 VAL N CA 1 +ATOM 26595 C C . VAL N 1 251 ? 7.467 37.055 82.798 1.00 160.78 ? 251 VAL N C 1 +ATOM 26596 O O . VAL N 1 251 ? 6.549 37.478 82.093 1.00 173.22 ? 251 VAL N O 1 +ATOM 26597 C CB . VAL N 1 251 ? 6.533 36.224 84.972 1.00 156.39 ? 251 VAL N CB 1 +ATOM 26598 C CG1 . VAL N 1 251 ? 6.326 35.008 85.870 1.00 146.95 ? 251 VAL N CG1 1 +ATOM 26599 C CG2 . VAL N 1 251 ? 7.272 37.340 85.703 1.00 154.39 ? 251 VAL N CG2 1 +ATOM 26600 N N . LYS N 1 252 ? 8.670 37.620 82.833 1.00 124.13 ? 252 LYS N N 1 +ATOM 26601 C CA . LYS N 1 252 ? 9.008 38.734 81.955 1.00 130.33 ? 252 LYS N CA 1 +ATOM 26602 C C . LYS N 1 252 ? 9.019 38.275 80.484 1.00 159.19 ? 252 LYS N C 1 +ATOM 26603 O O . LYS N 1 252 ? 8.449 38.926 79.604 1.00 140.22 ? 252 LYS N O 1 +ATOM 26604 C CB . LYS N 1 252 ? 10.358 39.321 82.380 1.00 123.39 ? 252 LYS N CB 1 +ATOM 26605 C CG . LYS N 1 252 ? 10.868 40.487 81.540 1.00 109.72 ? 252 LYS N CG 1 +ATOM 26606 C CD . LYS N 1 252 ? 12.219 40.958 82.064 1.00 123.28 ? 252 LYS N CD 1 +ATOM 26607 C CE . LYS N 1 252 ? 13.221 41.142 80.938 1.00 136.81 ? 252 LYS N CE 1 +ATOM 26608 N NZ . LYS N 1 252 ? 14.613 41.332 81.441 1.00 166.44 ? 252 LYS N NZ 1 +ATOM 26609 N N . TYR N 1 253 ? 9.674 37.145 80.231 1.00 175.51 ? 253 TYR N N 1 +ATOM 26610 C CA . TYR N 1 253 ? 9.792 36.610 78.871 1.00 152.86 ? 253 TYR N CA 1 +ATOM 26611 C C . TYR N 1 253 ? 8.499 35.947 78.437 1.00 131.51 ? 253 TYR N C 1 +ATOM 26612 O O . TYR N 1 253 ? 8.157 35.945 77.251 1.00 150.36 ? 253 TYR N O 1 +ATOM 26613 C CB . TYR N 1 253 ? 10.980 35.636 78.768 1.00 158.47 ? 253 TYR N CB 1 +ATOM 26614 C CG . TYR N 1 253 ? 12.319 36.363 78.819 1.00 149.30 ? 253 TYR N CG 1 +ATOM 26615 C CD1 . TYR N 1 253 ? 12.870 36.931 77.674 1.00 144.45 ? 253 TYR N CD1 1 +ATOM 26616 C CD2 . TYR N 1 253 ? 12.988 36.556 80.024 1.00 133.71 ? 253 TYR N CD2 1 +ATOM 26617 C CE1 . TYR N 1 253 ? 14.064 37.630 77.733 1.00 130.10 ? 253 TYR N CE1 1 +ATOM 26618 C CE2 . TYR N 1 253 ? 14.185 37.259 80.082 1.00 115.18 ? 253 TYR N CE2 1 +ATOM 26619 C CZ . TYR N 1 253 ? 14.713 37.796 78.933 1.00 109.14 ? 253 TYR N CZ 1 +ATOM 26620 O OH . TYR N 1 253 ? 15.909 38.485 78.972 1.00 99.31 ? 253 TYR N OH 1 +ATOM 26621 N N . ARG N 1 254 ? 7.797 35.364 79.401 1.00 147.85 ? 254 ARG N N 1 +ATOM 26622 C CA . ARG N 1 254 ? 6.440 34.873 79.169 1.00 166.04 ? 254 ARG N CA 1 +ATOM 26623 C C . ARG N 1 254 ? 5.547 36.016 78.682 1.00 174.34 ? 254 ARG N C 1 +ATOM 26624 O O . ARG N 1 254 ? 4.715 35.825 77.783 1.00 173.98 ? 254 ARG N O 1 +ATOM 26625 C CB . ARG N 1 254 ? 5.851 34.265 80.450 1.00 152.34 ? 254 ARG N CB 1 +ATOM 26626 C CG . ARG N 1 254 ? 4.486 33.634 80.245 1.00 140.21 ? 254 ARG N CG 1 +ATOM 26627 C CD . ARG N 1 254 ? 4.107 32.690 81.371 1.00 149.75 ? 254 ARG N CD 1 +ATOM 26628 N NE . ARG N 1 254 ? 4.957 31.501 81.461 1.00 141.57 ? 254 ARG N NE 1 +ATOM 26629 C CZ . ARG N 1 254 ? 5.853 31.266 82.419 1.00 145.88 ? 254 ARG N CZ 1 +ATOM 26630 N NH1 . ARG N 1 254 ? 6.077 32.154 83.376 1.00 142.92 ? 254 ARG N NH1 1 +ATOM 26631 N NH2 . ARG N 1 254 ? 6.540 30.131 82.407 1.00 151.35 ? 254 ARG N NH2 1 +ATOM 26632 N N . HIS N 1 255 ? 5.750 37.201 79.263 1.00 182.49 ? 255 HIS N N 1 +ATOM 26633 C CA . HIS N 1 255 ? 4.951 38.387 78.923 1.00 182.88 ? 255 HIS N CA 1 +ATOM 26634 C C . HIS N 1 255 ? 5.272 38.926 77.547 1.00 162.85 ? 255 HIS N C 1 +ATOM 26635 O O . HIS N 1 255 ? 4.388 39.407 76.838 1.00 124.33 ? 255 HIS N O 1 +ATOM 26636 C CB . HIS N 1 255 ? 5.159 39.512 79.939 1.00 191.61 ? 255 HIS N CB 1 +ATOM 26637 C CG . HIS N 1 255 ? 3.898 40.024 80.553 1.00 214.87 ? 255 HIS N CG 1 +ATOM 26638 N ND1 . HIS N 1 255 ? 3.094 40.939 79.907 1.00 222.83 ? 255 HIS N ND1 1 +ATOM 26639 C CD2 . HIS N 1 255 ? 3.356 39.843 81.778 1.00 207.92 ? 255 HIS N CD2 1 +ATOM 26640 C CE1 . HIS N 1 255 ? 2.079 41.256 80.691 1.00 198.21 ? 255 HIS N CE1 1 +ATOM 26641 N NE2 . HIS N 1 255 ? 2.213 40.602 81.830 1.00 198.74 ? 255 HIS N NE2 1 +ATOM 26642 N N . MET N 1 256 ? 6.529 38.802 77.135 1.00 167.12 ? 256 MET N N 1 +ATOM 26643 C CA . MET N 1 256 ? 6.910 39.242 75.787 1.00 179.35 ? 256 MET N CA 1 +ATOM 26644 C C . MET N 1 256 ? 6.277 38.369 74.670 1.00 166.46 ? 256 MET N C 1 +ATOM 26645 O O . MET N 1 256 ? 6.074 38.846 73.552 1.00 118.44 ? 256 MET N O 1 +ATOM 26646 C CB . MET N 1 256 ? 8.444 39.304 75.656 1.00 181.00 ? 256 MET N CB 1 +ATOM 26647 C CG . MET N 1 256 ? 9.119 40.116 76.757 1.00 159.28 ? 256 MET N CG 1 +ATOM 26648 S SD . MET N 1 256 ? 10.790 40.673 76.397 1.00 165.70 ? 256 MET N SD 1 +ATOM 26649 C CE . MET N 1 256 ? 10.470 41.880 75.107 1.00 181.38 ? 256 MET N CE 1 +ATOM 26650 N N . SER N 1 257 ? 5.931 37.120 74.998 1.00 169.94 ? 257 SER N N 1 +ATOM 26651 C CA . SER N 1 257 ? 5.255 36.196 74.065 1.00 147.50 ? 257 SER N CA 1 +ATOM 26652 C C . SER N 1 257 ? 3.769 36.479 73.870 1.00 112.99 ? 257 SER N C 1 +ATOM 26653 O O . SER N 1 257 ? 3.401 37.294 73.038 1.00 118.51 ? 257 SER N O 1 +ATOM 26654 C CB . SER N 1 257 ? 5.395 34.754 74.559 1.00 167.94 ? 257 SER N CB 1 +ATOM 26655 O OG . SER N 1 257 ? 6.700 34.483 75.004 1.00 171.45 ? 257 SER N OG 1 +ATOM 26656 N N . LEU O 1 2 ? 35.991 55.471 80.076 1.00 114.75 ? 2 LEU O N 1 +ATOM 26657 C CA . LEU O 1 2 ? 35.157 55.420 78.831 1.00 123.13 ? 2 LEU O CA 1 +ATOM 26658 C C . LEU O 1 2 ? 36.054 55.253 77.582 1.00 130.00 ? 2 LEU O C 1 +ATOM 26659 O O . LEU O 1 2 ? 36.222 56.182 76.751 1.00 97.42 ? 2 LEU O O 1 +ATOM 26660 C CB . LEU O 1 2 ? 34.251 56.658 78.715 1.00 138.09 ? 2 LEU O CB 1 +ATOM 26661 C CG . LEU O 1 2 ? 33.185 56.914 79.808 1.00 139.66 ? 2 LEU O CG 1 +ATOM 26662 C CD1 . LEU O 1 2 ? 32.436 58.209 79.497 1.00 132.01 ? 2 LEU O CD1 1 +ATOM 26663 C CD2 . LEU O 1 2 ? 32.193 55.764 80.014 1.00 126.69 ? 2 LEU O CD2 1 +ATOM 26664 N N . THR O 1 3 ? 36.731 54.102 77.565 1.00 141.01 ? 3 THR O N 1 +ATOM 26665 C CA . THR O 1 3 ? 37.366 53.530 76.372 1.00 139.22 ? 3 THR O CA 1 +ATOM 26666 C C . THR O 1 3 ? 37.161 51.998 76.340 1.00 119.08 ? 3 THR O C 1 +ATOM 26667 O O . THR O 1 3 ? 37.600 51.306 75.421 1.00 117.32 ? 3 THR O O 1 +ATOM 26668 C CB . THR O 1 3 ? 38.886 53.826 76.317 1.00 137.63 ? 3 THR O CB 1 +ATOM 26669 O OG1 . THR O 1 3 ? 39.563 53.104 77.360 1.00 123.09 ? 3 THR O OG1 1 +ATOM 26670 C CG2 . THR O 1 3 ? 39.163 55.337 76.414 1.00 123.11 ? 3 THR O CG2 1 +ATOM 26671 N N . ALA O 1 4 ? 36.550 51.470 77.389 1.00 115.31 ? 4 ALA O N 1 +ATOM 26672 C CA . ALA O 1 4 ? 35.860 50.182 77.318 1.00 107.56 ? 4 ALA O CA 1 +ATOM 26673 C C . ALA O 1 4 ? 34.555 50.376 76.511 1.00 86.67 ? 4 ALA O C 1 +ATOM 26674 O O . ALA O 1 4 ? 34.328 51.439 75.949 1.00 64.04 ? 4 ALA O O 1 +ATOM 26675 C CB . ALA O 1 4 ? 35.593 49.652 78.730 1.00 114.98 ? 4 ALA O CB 1 +ATOM 26676 N N . PRO O 1 5 ? 33.699 49.355 76.427 1.00 88.41 ? 5 PRO O N 1 +ATOM 26677 C CA . PRO O 1 5 ? 32.717 49.555 75.370 1.00 108.24 ? 5 PRO O CA 1 +ATOM 26678 C C . PRO O 1 5 ? 31.540 50.425 75.809 1.00 118.36 ? 5 PRO O C 1 +ATOM 26679 O O . PRO O 1 5 ? 31.419 50.729 76.993 1.00 166.35 ? 5 PRO O O 1 +ATOM 26680 C CB . PRO O 1 5 ? 32.252 48.132 75.073 1.00 154.35 ? 5 PRO O CB 1 +ATOM 26681 C CG . PRO O 1 5 ? 32.477 47.356 76.350 1.00 135.39 ? 5 PRO O CG 1 +ATOM 26682 C CD . PRO O 1 5 ? 33.507 48.084 77.160 1.00 97.23 ? 5 PRO O CD 1 +ATOM 26683 N N . PRO O 1 6 ? 30.694 50.862 74.854 1.00 121.66 ? 6 PRO O N 1 +ATOM 26684 C CA . PRO O 1 6 ? 29.385 51.460 75.170 1.00 114.86 ? 6 PRO O CA 1 +ATOM 26685 C C . PRO O 1 6 ? 28.351 50.413 75.530 1.00 114.59 ? 6 PRO O C 1 +ATOM 26686 O O . PRO O 1 6 ? 28.443 49.266 75.087 1.00 102.32 ? 6 PRO O O 1 +ATOM 26687 C CB . PRO O 1 6 ? 28.981 52.196 73.889 1.00 106.20 ? 6 PRO O CB 1 +ATOM 26688 C CG . PRO O 1 6 ? 29.841 51.650 72.813 1.00 113.48 ? 6 PRO O CG 1 +ATOM 26689 C CD . PRO O 1 6 ? 31.019 50.936 73.422 1.00 128.66 ? 6 PRO O CD 1 +ATOM 26690 N N . LYS O 1 7 ? 27.383 50.796 76.355 1.00 131.20 ? 7 LYS O N 1 +ATOM 26691 C CA . LYS O 1 7 ? 26.432 49.826 76.894 1.00 155.33 ? 7 LYS O CA 1 +ATOM 26692 C C . LYS O 1 7 ? 25.147 49.778 76.075 1.00 137.41 ? 7 LYS O C 1 +ATOM 26693 O O . LYS O 1 7 ? 24.925 50.624 75.192 1.00 86.23 ? 7 LYS O O 1 +ATOM 26694 C CB . LYS O 1 7 ? 26.164 50.088 78.388 1.00 159.98 ? 7 LYS O CB 1 +ATOM 26695 C CG . LYS O 1 7 ? 27.383 49.624 79.253 1.00 155.50 ? 7 LYS O CG 1 +ATOM 26696 C CD . LYS O 1 7 ? 27.487 48.092 79.330 1.00 168.85 ? 7 LYS O CD 1 +ATOM 26697 C CE . LYS O 1 7 ? 28.922 47.642 79.586 1.00 164.55 ? 7 LYS O CE 1 +ATOM 26698 N NZ . LYS O 1 7 ? 28.989 46.331 80.294 1.00 180.06 ? 7 LYS O NZ 1 +ATOM 26699 N N . GLU O 1 8 ? 24.318 48.774 76.376 1.00 132.00 ? 8 GLU O N 1 +ATOM 26700 C CA . GLU O 1 8 ? 23.161 48.434 75.553 1.00 134.93 ? 8 GLU O CA 1 +ATOM 26701 C C . GLU O 1 8 ? 22.105 49.521 75.460 1.00 129.64 ? 8 GLU O C 1 +ATOM 26702 O O . GLU O 1 8 ? 21.511 49.912 76.464 1.00 126.92 ? 8 GLU O O 1 +ATOM 26703 C CB . GLU O 1 8 ? 22.464 47.212 76.104 1.00 122.34 ? 8 GLU O CB 1 +ATOM 26704 C CG . GLU O 1 8 ? 22.235 46.057 75.190 1.00 129.49 ? 8 GLU O CG 1 +ATOM 26705 C CD . GLU O 1 8 ? 21.457 44.948 75.889 1.00 153.24 ? 8 GLU O CD 1 +ATOM 26706 O OE1 . GLU O 1 8 ? 21.872 44.474 76.972 1.00 132.85 ? 8 GLU O OE1 1 +ATOM 26707 O OE2 . GLU O 1 8 ? 20.477 44.450 75.329 1.00 216.98 ? 8 GLU O OE2 1 +ATOM 26708 N N . ALA O 1 9 ? 21.893 50.002 74.240 1.00 124.01 ? 9 ALA O N 1 +ATOM 26709 C CA . ALA O 1 9 ? 20.800 50.895 73.920 1.00 106.70 ? 9 ALA O CA 1 +ATOM 26710 C C . ALA O 1 9 ? 19.657 50.083 73.290 1.00 116.64 ? 9 ALA O C 1 +ATOM 26711 O O . ALA O 1 9 ? 19.768 49.596 72.158 1.00 142.41 ? 9 ALA O O 1 +ATOM 26712 C CB . ALA O 1 9 ? 21.280 51.978 72.964 1.00 86.94 ? 9 ALA O CB 1 +ATOM 26713 N N . ALA O 1 10 ? 18.559 49.974 74.030 1.00 100.50 ? 10 ALA O N 1 +ATOM 26714 C CA . ALA O 1 10 ? 17.395 49.142 73.679 1.00 105.26 ? 10 ALA O CA 1 +ATOM 26715 C C . ALA O 1 10 ? 17.612 47.701 74.098 1.00 103.63 ? 10 ALA O C 1 +ATOM 26716 O O . ALA O 1 10 ? 18.740 47.277 74.340 1.00 99.16 ? 10 ALA O O 1 +ATOM 26717 C CB . ALA O 1 10 ? 17.045 49.214 72.197 1.00 105.97 ? 10 ALA O CB 1 +ATOM 26718 N N . ARG O 1 11 ? 16.506 46.972 74.243 1.00 115.31 ? 11 ARG O N 1 +ATOM 26719 C CA . ARG O 1 11 ? 16.534 45.569 74.679 1.00 136.07 ? 11 ARG O CA 1 +ATOM 26720 C C . ARG O 1 11 ? 16.300 44.660 73.482 1.00 128.63 ? 11 ARG O C 1 +ATOM 26721 O O . ARG O 1 11 ? 15.618 45.050 72.548 1.00 130.66 ? 11 ARG O O 1 +ATOM 26722 C CB . ARG O 1 11 ? 15.444 45.289 75.736 1.00 152.66 ? 11 ARG O CB 1 +ATOM 26723 C CG . ARG O 1 11 ? 14.016 45.409 75.225 1.00 155.76 ? 11 ARG O CG 1 +ATOM 26724 C CD . ARG O 1 11 ? 13.051 45.765 76.352 1.00 166.24 ? 11 ARG O CD 1 +ATOM 26725 N NE . ARG O 1 11 ? 12.526 47.124 76.220 1.00 198.70 ? 11 ARG O NE 1 +ATOM 26726 C CZ . ARG O 1 11 ? 11.622 47.657 77.041 1.00 192.18 ? 11 ARG O CZ 1 +ATOM 26727 N NH1 . ARG O 1 11 ? 11.120 46.936 78.033 1.00 193.74 ? 11 ARG O NH1 1 +ATOM 26728 N NH2 . ARG O 1 11 ? 11.205 48.905 76.864 1.00 169.89 ? 11 ARG O NH2 1 +ATOM 26729 N N . PRO O 1 12 ? 16.832 43.428 73.519 1.00 109.59 ? 12 PRO O N 1 +ATOM 26730 C CA . PRO O 1 12 ? 16.393 42.454 72.538 1.00 94.73 ? 12 PRO O CA 1 +ATOM 26731 C C . PRO O 1 12 ? 14.929 42.121 72.779 1.00 94.21 ? 12 PRO O C 1 +ATOM 26732 O O . PRO O 1 12 ? 14.572 41.579 73.833 1.00 112.51 ? 12 PRO O O 1 +ATOM 26733 C CB . PRO O 1 12 ? 17.289 41.230 72.802 1.00 77.30 ? 12 PRO O CB 1 +ATOM 26734 C CG . PRO O 1 12 ? 18.384 41.712 73.667 1.00 90.31 ? 12 PRO O CG 1 +ATOM 26735 C CD . PRO O 1 12 ? 17.810 42.859 74.453 1.00 101.19 ? 12 PRO O CD 1 +ATOM 26736 N N . THR O 1 13 ? 14.081 42.505 71.838 1.00 76.27 ? 13 THR O N 1 +ATOM 26737 C CA . THR O 1 13 ? 12.713 42.009 71.809 1.00 91.19 ? 13 THR O CA 1 +ATOM 26738 C C . THR O 1 13 ? 12.617 40.772 70.922 1.00 92.50 ? 13 THR O C 1 +ATOM 26739 O O . THR O 1 13 ? 13.492 40.558 70.070 1.00 150.53 ? 13 THR O O 1 +ATOM 26740 C CB . THR O 1 13 ? 11.782 43.096 71.264 1.00 95.21 ? 13 THR O CB 1 +ATOM 26741 O OG1 . THR O 1 13 ? 10.420 42.675 71.436 1.00 95.80 ? 13 THR O OG1 1 +ATOM 26742 C CG2 . THR O 1 13 ? 12.086 43.415 69.761 1.00 84.29 ? 13 THR O CG2 1 +ATOM 26743 N N . LEU O 1 14 ? 11.564 39.976 71.055 1.00 71.26 ? 14 LEU O N 1 +ATOM 26744 C CA . LEU O 1 14 ? 11.344 38.974 70.018 1.00 70.54 ? 14 LEU O CA 1 +ATOM 26745 C C . LEU O 1 14 ? 10.800 39.662 68.756 1.00 63.23 ? 14 LEU O C 1 +ATOM 26746 O O . LEU O 1 14 ? 10.365 40.783 68.805 1.00 53.32 ? 14 LEU O O 1 +ATOM 26747 C CB . LEU O 1 14 ? 10.506 37.785 70.495 1.00 77.16 ? 14 LEU O CB 1 +ATOM 26748 C CG . LEU O 1 14 ? 9.169 38.055 71.130 1.00 93.60 ? 14 LEU O CG 1 +ATOM 26749 C CD1 . LEU O 1 14 ? 8.182 36.936 70.815 1.00 94.01 ? 14 LEU O CD1 1 +ATOM 26750 C CD2 . LEU O 1 14 ? 9.362 38.167 72.621 1.00 100.87 ? 14 LEU O CD2 1 +ATOM 26751 N N . MET O 1 15 ? 10.959 39.045 67.596 1.00 88.22 ? 15 MET O N 1 +ATOM 26752 C CA . MET O 1 15 ? 11.026 39.801 66.327 1.00 110.61 ? 15 MET O CA 1 +ATOM 26753 C C . MET O 1 15 ? 9.670 40.423 65.965 1.00 109.61 ? 15 MET O C 1 +ATOM 26754 O O . MET O 1 15 ? 8.670 39.712 65.860 1.00 85.90 ? 15 MET O O 1 +ATOM 26755 C CB . MET O 1 15 ? 11.549 38.914 65.162 1.00 138.40 ? 15 MET O CB 1 +ATOM 26756 C CG . MET O 1 15 ? 12.305 39.687 64.076 1.00 144.24 ? 15 MET O CG 1 +ATOM 26757 S SD . MET O 1 15 ? 12.258 39.135 62.342 1.00 121.25 ? 15 MET O SD 1 +ATOM 26758 C CE . MET O 1 15 ? 10.713 38.220 62.212 1.00 137.84 ? 15 MET O CE 1 +ATOM 26759 N N . PRO O 1 16 ? 9.654 41.749 65.731 1.00 114.65 ? 16 PRO O N 1 +ATOM 26760 C CA . PRO O 1 16 ? 8.436 42.549 65.568 1.00 122.16 ? 16 PRO O CA 1 +ATOM 26761 C C . PRO O 1 16 ? 7.637 42.212 64.312 1.00 112.90 ? 16 PRO O C 1 +ATOM 26762 O O . PRO O 1 16 ? 7.717 42.906 63.309 1.00 81.39 ? 16 PRO O O 1 +ATOM 26763 C CB . PRO O 1 16 ? 8.966 43.989 65.508 1.00 121.43 ? 16 PRO O CB 1 +ATOM 26764 C CG . PRO O 1 16 ? 10.375 43.850 65.066 1.00 114.92 ? 16 PRO O CG 1 +ATOM 26765 C CD . PRO O 1 16 ? 10.860 42.592 65.714 1.00 112.82 ? 16 PRO O CD 1 +ATOM 26766 N N . ARG O 1 17 ? 6.831 41.160 64.403 1.00 127.29 ? 17 ARG O N 1 +ATOM 26767 C CA . ARG O 1 17 ? 5.878 40.812 63.349 1.00 126.51 ? 17 ARG O CA 1 +ATOM 26768 C C . ARG O 1 17 ? 4.552 41.538 63.580 1.00 124.24 ? 17 ARG O C 1 +ATOM 26769 O O . ARG O 1 17 ? 4.185 41.783 64.717 1.00 116.42 ? 17 ARG O O 1 +ATOM 26770 C CB . ARG O 1 17 ? 5.651 39.300 63.343 1.00 138.37 ? 17 ARG O CB 1 +ATOM 26771 C CG . ARG O 1 17 ? 6.668 38.538 62.515 1.00 166.03 ? 17 ARG O CG 1 +ATOM 26772 C CD . ARG O 1 17 ? 6.713 37.051 62.836 1.00 171.23 ? 17 ARG O CD 1 +ATOM 26773 N NE . ARG O 1 17 ? 7.452 36.776 64.065 1.00 173.36 ? 17 ARG O NE 1 +ATOM 26774 C CZ . ARG O 1 17 ? 7.543 35.573 64.622 1.00 200.38 ? 17 ARG O CZ 1 +ATOM 26775 N NH1 . ARG O 1 17 ? 6.958 34.533 64.037 1.00 219.79 ? 17 ARG O NH1 1 +ATOM 26776 N NH2 . ARG O 1 17 ? 8.226 35.407 65.748 1.00 185.55 ? 17 ARG O NH2 1 +ATOM 26777 N N . ALA O 1 18 ? 3.854 41.917 62.512 1.00 146.98 ? 18 ALA O N 1 +ATOM 26778 C CA . ALA O 1 18 ? 2.621 42.716 62.645 1.00 138.23 ? 18 ALA O CA 1 +ATOM 26779 C C . ALA O 1 18 ? 1.361 41.960 62.206 1.00 132.04 ? 18 ALA O C 1 +ATOM 26780 O O . ALA O 1 18 ? 1.023 40.931 62.792 1.00 79.94 ? 18 ALA O O 1 +ATOM 26781 C CB . ALA O 1 18 ? 2.747 44.048 61.904 1.00 138.84 ? 18 ALA O CB 1 +ATOM 26782 N N . GLN O 1 19 ? 0.671 42.470 61.184 1.00 150.10 ? 19 GLN O N 1 +ATOM 26783 C CA . GLN O 1 19 ? -0.723 42.088 60.942 1.00 163.23 ? 19 GLN O CA 1 +ATOM 26784 C C . GLN O 1 19 ? -0.842 40.651 60.439 1.00 149.08 ? 19 GLN O C 1 +ATOM 26785 O O . GLN O 1 19 ? -1.649 39.852 60.938 1.00 104.56 ? 19 GLN O O 1 +ATOM 26786 C CB . GLN O 1 19 ? -1.367 43.049 59.934 1.00 169.22 ? 19 GLN O CB 1 +ATOM 26787 C CG . GLN O 1 19 ? -2.860 42.828 59.729 1.00 178.92 ? 19 GLN O CG 1 +ATOM 26788 C CD . GLN O 1 19 ? -3.639 42.864 61.034 1.00 192.41 ? 19 GLN O CD 1 +ATOM 26789 O OE1 . GLN O 1 19 ? -3.743 43.907 61.680 1.00 203.80 ? 19 GLN O OE1 1 +ATOM 26790 N NE2 . GLN O 1 19 ? -4.190 41.720 61.427 1.00 199.26 ? 19 GLN O NE2 1 +ATOM 26791 N N . SER O 1 20 ? -0.052 40.358 59.412 1.00 143.70 ? 20 SER O N 1 +ATOM 26792 C CA . SER O 1 20 ? 0.061 39.023 58.863 1.00 128.38 ? 20 SER O CA 1 +ATOM 26793 C C . SER O 1 20 ? 0.161 37.987 59.983 1.00 120.66 ? 20 SER O C 1 +ATOM 26794 O O . SER O 1 20 ? -0.571 36.990 59.985 1.00 95.29 ? 20 SER O O 1 +ATOM 26795 C CB . SER O 1 20 ? 1.298 38.962 57.959 1.00 140.82 ? 20 SER O CB 1 +ATOM 26796 O OG . SER O 1 20 ? 1.287 40.018 57.003 1.00 123.82 ? 20 SER O OG 1 +ATOM 26797 N N . TYR O 1 21 ? 1.072 38.231 60.923 1.00 130.31 ? 21 TYR O N 1 +ATOM 26798 C CA . TYR O 1 21 ? 1.256 37.361 62.090 1.00 164.17 ? 21 TYR O CA 1 +ATOM 26799 C C . TYR O 1 21 ? -0.025 37.169 62.910 1.00 149.84 ? 21 TYR O C 1 +ATOM 26800 O O . TYR O 1 21 ? -0.409 36.038 63.235 1.00 131.01 ? 21 TYR O O 1 +ATOM 26801 C CB . TYR O 1 21 ? 2.341 37.927 63.003 1.00 174.90 ? 21 TYR O CB 1 +ATOM 26802 C CG . TYR O 1 21 ? 2.614 37.063 64.209 1.00 165.05 ? 21 TYR O CG 1 +ATOM 26803 C CD1 . TYR O 1 21 ? 3.351 35.897 64.086 1.00 175.12 ? 21 TYR O CD1 1 +ATOM 26804 C CD2 . TYR O 1 21 ? 2.114 37.395 65.469 1.00 130.80 ? 21 TYR O CD2 1 +ATOM 26805 C CE1 . TYR O 1 21 ? 3.605 35.103 65.185 1.00 183.84 ? 21 TYR O CE1 1 +ATOM 26806 C CE2 . TYR O 1 21 ? 2.374 36.609 66.575 1.00 109.39 ? 21 TYR O CE2 1 +ATOM 26807 C CZ . TYR O 1 21 ? 3.119 35.469 66.427 1.00 121.70 ? 21 TYR O CZ 1 +ATOM 26808 O OH . TYR O 1 21 ? 3.422 34.658 67.492 1.00 120.25 ? 21 TYR O OH 1 +ATOM 26809 N N . LYS O 1 22 ? -0.676 38.277 63.239 1.00 134.49 ? 22 LYS O N 1 +ATOM 26810 C CA . LYS O 1 22 ? -1.885 38.233 64.035 1.00 150.45 ? 22 LYS O CA 1 +ATOM 26811 C C . LYS O 1 22 ? -2.970 37.391 63.374 1.00 144.01 ? 22 LYS O C 1 +ATOM 26812 O O . LYS O 1 22 ? -3.724 36.681 64.052 1.00 128.97 ? 22 LYS O O 1 +ATOM 26813 C CB . LYS O 1 22 ? -2.396 39.656 64.289 1.00 186.81 ? 22 LYS O CB 1 +ATOM 26814 C CG . LYS O 1 22 ? -1.799 40.300 65.528 1.00 209.84 ? 22 LYS O CG 1 +ATOM 26815 C CD . LYS O 1 22 ? -2.554 39.846 66.785 1.00 199.04 ? 22 LYS O CD 1 +ATOM 26816 C CE . LYS O 1 22 ? -3.518 40.946 67.253 1.00 181.03 ? 22 LYS O CE 1 +ATOM 26817 N NZ . LYS O 1 22 ? -2.786 42.159 67.703 1.00 170.88 ? 22 LYS O NZ 1 +ATOM 26818 N N . ASP O 1 23 ? -3.116 37.556 62.062 1.00 141.72 ? 23 ASP O N 1 +ATOM 26819 C CA . ASP O 1 23 ? -4.073 36.762 61.290 1.00 133.22 ? 23 ASP O CA 1 +ATOM 26820 C C . ASP O 1 23 ? -3.673 35.299 61.349 1.00 114.30 ? 23 ASP O C 1 +ATOM 26821 O O . ASP O 1 23 ? -4.519 34.415 61.514 1.00 113.03 ? 23 ASP O O 1 +ATOM 26822 C CB . ASP O 1 23 ? -4.116 37.241 59.828 1.00 124.68 ? 23 ASP O CB 1 +ATOM 26823 C CG . ASP O 1 23 ? -4.729 38.604 59.688 1.00 123.52 ? 23 ASP O CG 1 +ATOM 26824 O OD1 . ASP O 1 23 ? -5.744 38.861 60.372 1.00 136.80 ? 23 ASP O OD1 1 +ATOM 26825 O OD2 . ASP O 1 23 ? -4.208 39.422 58.895 1.00 115.16 ? 23 ASP O OD2 1 +ATOM 26826 N N . LEU O 1 24 ? -2.382 35.057 61.151 1.00 105.02 ? 24 LEU O N 1 +ATOM 26827 C CA . LEU O 1 24 ? -1.850 33.703 60.992 1.00 147.70 ? 24 LEU O CA 1 +ATOM 26828 C C . LEU O 1 24 ? -2.010 32.891 62.278 1.00 149.12 ? 24 LEU O C 1 +ATOM 26829 O O . LEU O 1 24 ? -2.250 31.667 62.231 1.00 141.18 ? 24 LEU O O 1 +ATOM 26830 C CB . LEU O 1 24 ? -0.366 33.771 60.598 1.00 166.13 ? 24 LEU O CB 1 +ATOM 26831 C CG . LEU O 1 24 ? 0.396 32.450 60.400 1.00 151.64 ? 24 LEU O CG 1 +ATOM 26832 C CD1 . LEU O 1 24 ? 0.222 31.926 58.981 1.00 143.44 ? 24 LEU O CD1 1 +ATOM 26833 C CD2 . LEU O 1 24 ? 1.870 32.645 60.723 1.00 141.19 ? 24 LEU O CD2 1 +ATOM 26834 N N . THR O 1 25 ? -1.883 33.574 63.418 1.00 152.31 ? 25 THR O N 1 +ATOM 26835 C CA . THR O 1 25 ? -1.957 32.915 64.729 1.00 163.90 ? 25 THR O CA 1 +ATOM 26836 C C . THR O 1 25 ? -3.397 32.573 65.124 1.00 184.14 ? 25 THR O C 1 +ATOM 26837 O O . THR O 1 25 ? -3.687 31.436 65.526 1.00 137.69 ? 25 THR O O 1 +ATOM 26838 C CB . THR O 1 25 ? -1.331 33.785 65.836 1.00 132.20 ? 25 THR O CB 1 +ATOM 26839 O OG1 . THR O 1 25 ? -1.795 35.132 65.705 1.00 102.20 ? 25 THR O OG1 1 +ATOM 26840 C CG2 . THR O 1 25 ? 0.176 33.758 65.733 1.00 120.25 ? 25 THR O CG2 1 +ATOM 26841 N N . HIS O 1 26 ? -4.297 33.540 64.935 1.00 194.89 ? 26 HIS O N 1 +ATOM 26842 C CA . HIS O 1 26 ? -5.708 33.383 65.287 1.00 168.18 ? 26 HIS O CA 1 +ATOM 26843 C C . HIS O 1 26 ? -6.505 32.712 64.150 1.00 133.69 ? 26 HIS O C 1 +ATOM 26844 O O . HIS O 1 26 ? -7.667 33.009 63.934 1.00 138.01 ? 26 HIS O O 1 +ATOM 26845 C CB . HIS O 1 26 ? -6.311 34.750 65.650 1.00 167.76 ? 26 HIS O CB 1 +ATOM 26846 C CG . HIS O 1 26 ? -5.686 35.384 66.862 1.00 163.93 ? 26 HIS O CG 1 +ATOM 26847 N ND1 . HIS O 1 26 ? -4.397 35.876 66.864 1.00 172.96 ? 26 HIS O ND1 1 +ATOM 26848 C CD2 . HIS O 1 26 ? -6.165 35.586 68.115 1.00 144.19 ? 26 HIS O CD2 1 +ATOM 26849 C CE1 . HIS O 1 26 ? -4.113 36.362 68.061 1.00 154.71 ? 26 HIS O CE1 1 +ATOM 26850 N NE2 . HIS O 1 26 ? -5.162 36.183 68.843 1.00 126.85 ? 26 HIS O NE2 1 +ATOM 26851 N N . LEU O 1 27 ? -5.892 31.752 63.471 1.00 138.10 ? 27 LEU O N 1 +ATOM 26852 C CA . LEU O 1 27 ? -6.600 30.939 62.487 1.00 128.77 ? 27 LEU O CA 1 +ATOM 26853 C C . LEU O 1 27 ? -7.234 29.710 63.144 1.00 117.60 ? 27 LEU O C 1 +ATOM 26854 O O . LEU O 1 27 ? -6.611 29.047 63.978 1.00 93.72 ? 27 LEU O O 1 +ATOM 26855 C CB . LEU O 1 27 ? -5.647 30.471 61.388 1.00 156.75 ? 27 LEU O CB 1 +ATOM 26856 C CG . LEU O 1 27 ? -5.467 31.441 60.221 1.00 169.59 ? 27 LEU O CG 1 +ATOM 26857 C CD1 . LEU O 1 27 ? -4.278 31.037 59.363 1.00 173.67 ? 27 LEU O CD1 1 +ATOM 26858 C CD2 . LEU O 1 27 ? -6.731 31.520 59.379 1.00 169.10 ? 27 LEU O CD2 1 +ATOM 26859 N N . PRO O 1 28 ? -8.476 29.391 62.754 1.00 107.33 ? 28 PRO O N 1 +ATOM 26860 C CA . PRO O 1 28 ? -9.215 28.280 63.372 1.00 109.94 ? 28 PRO O CA 1 +ATOM 26861 C C . PRO O 1 28 ? -8.506 26.976 63.109 1.00 96.31 ? 28 PRO O C 1 +ATOM 26862 O O . PRO O 1 28 ? -8.180 26.704 61.975 1.00 91.66 ? 28 PRO O O 1 +ATOM 26863 C CB . PRO O 1 28 ? -10.574 28.317 62.651 1.00 119.21 ? 28 PRO O CB 1 +ATOM 26864 C CG . PRO O 1 28 ? -10.315 29.060 61.378 1.00 103.16 ? 28 PRO O CG 1 +ATOM 26865 C CD . PRO O 1 28 ? -9.272 30.075 61.718 1.00 103.96 ? 28 PRO O CD 1 +ATOM 26866 N N . ALA O 1 29 ? -8.291 26.174 64.146 1.00 118.03 ? 29 ALA O N 1 +ATOM 26867 C CA . ALA O 1 29 ? -7.415 25.008 64.044 1.00 111.96 ? 29 ALA O CA 1 +ATOM 26868 C C . ALA O 1 29 ? -8.046 23.857 63.224 1.00 116.71 ? 29 ALA O C 1 +ATOM 26869 O O . ALA O 1 29 ? -9.269 23.687 63.198 1.00 101.42 ? 29 ALA O O 1 +ATOM 26870 C CB . ALA O 1 29 ? -7.001 24.529 65.431 1.00 94.85 ? 29 ALA O CB 1 +ATOM 26871 N N . PRO O 1 30 ? -7.205 23.097 62.499 1.00 125.37 ? 30 PRO O N 1 +ATOM 26872 C CA . PRO O 1 30 ? -7.635 21.917 61.740 1.00 124.27 ? 30 PRO O CA 1 +ATOM 26873 C C . PRO O 1 30 ? -7.889 20.703 62.645 1.00 107.62 ? 30 PRO O C 1 +ATOM 26874 O O . PRO O 1 30 ? -7.622 20.776 63.851 1.00 67.31 ? 30 PRO O O 1 +ATOM 26875 C CB . PRO O 1 30 ? -6.432 21.631 60.850 1.00 129.00 ? 30 PRO O CB 1 +ATOM 26876 C CG . PRO O 1 30 ? -5.261 22.107 61.637 1.00 122.51 ? 30 PRO O CG 1 +ATOM 26877 C CD . PRO O 1 30 ? -5.741 23.276 62.449 1.00 131.90 ? 30 PRO O CD 1 +ATOM 26878 N N . THR O 1 31 ? -8.368 19.600 62.058 1.00 96.52 ? 31 THR O N 1 +ATOM 26879 C CA . THR O 1 31 ? -8.683 18.380 62.829 1.00 110.73 ? 31 THR O CA 1 +ATOM 26880 C C . THR O 1 31 ? -7.437 17.711 63.399 1.00 113.56 ? 31 THR O C 1 +ATOM 26881 O O . THR O 1 31 ? -7.496 17.039 64.420 1.00 132.07 ? 31 THR O O 1 +ATOM 26882 C CB . THR O 1 31 ? -9.487 17.334 62.010 1.00 114.05 ? 31 THR O CB 1 +ATOM 26883 O OG1 . THR O 1 31 ? -8.831 17.048 60.776 1.00 110.45 ? 31 THR O OG1 1 +ATOM 26884 C CG2 . THR O 1 31 ? -10.900 17.837 61.718 1.00 135.95 ? 31 THR O CG2 1 +ATOM 26885 N N . GLY O 1 32 ? -6.310 17.908 62.732 1.00 134.12 ? 32 GLY O N 1 +ATOM 26886 C CA . GLY O 1 32 ? -5.004 17.555 63.283 1.00 143.72 ? 32 GLY O CA 1 +ATOM 26887 C C . GLY O 1 32 ? -3.944 18.380 62.577 1.00 146.11 ? 32 GLY O C 1 +ATOM 26888 O O . GLY O 1 32 ? -4.175 18.851 61.462 1.00 127.07 ? 32 GLY O O 1 +ATOM 26889 N N . LYS O 1 33 ? -2.801 18.599 63.221 1.00 137.39 ? 33 LYS O N 1 +ATOM 26890 C CA . LYS O 1 33 ? -1.730 19.335 62.562 1.00 128.20 ? 33 LYS O CA 1 +ATOM 26891 C C . LYS O 1 33 ? -1.159 18.500 61.414 1.00 153.13 ? 33 LYS O C 1 +ATOM 26892 O O . LYS O 1 33 ? -1.187 17.272 61.465 1.00 134.59 ? 33 LYS O O 1 +ATOM 26893 C CB . LYS O 1 33 ? -0.633 19.738 63.541 1.00 111.02 ? 33 LYS O CB 1 +ATOM 26894 C CG . LYS O 1 33 ? -0.845 21.099 64.181 1.00 108.16 ? 33 LYS O CG 1 +ATOM 26895 C CD . LYS O 1 33 ? 0.182 21.340 65.273 1.00 138.38 ? 33 LYS O CD 1 +ATOM 26896 C CE . LYS O 1 33 ? -0.348 22.308 66.315 1.00 144.96 ? 33 LYS O CE 1 +ATOM 26897 N NZ . LYS O 1 33 ? 0.574 22.424 67.477 1.00 180.45 ? 33 LYS O NZ 1 +ATOM 26898 N N . ILE O 1 34 ? -0.664 19.171 60.375 1.00 167.29 ? 34 ILE O N 1 +ATOM 26899 C CA . ILE O 1 34 ? -0.143 18.489 59.201 1.00 144.10 ? 34 ILE O CA 1 +ATOM 26900 C C . ILE O 1 34 ? 1.394 18.566 59.238 1.00 153.65 ? 34 ILE O C 1 +ATOM 26901 O O . ILE O 1 34 ? 1.981 19.533 59.742 1.00 187.39 ? 34 ILE O O 1 +ATOM 26902 C CB . ILE O 1 34 ? -0.767 19.064 57.904 1.00 145.26 ? 34 ILE O CB 1 +ATOM 26903 C CG1 . ILE O 1 34 ? -2.266 18.759 57.862 1.00 145.51 ? 34 ILE O CG1 1 +ATOM 26904 C CG2 . ILE O 1 34 ? -0.140 18.469 56.650 1.00 180.95 ? 34 ILE O CG2 1 +ATOM 26905 C CD1 . ILE O 1 34 ? -3.126 19.999 57.850 1.00 176.92 ? 34 ILE O CD1 1 +ATOM 26906 N N . PHE O 1 35 ? 2.025 17.469 58.838 1.00 124.71 ? 35 PHE O N 1 +ATOM 26907 C CA . PHE O 1 35 ? 3.468 17.356 58.819 1.00 98.26 ? 35 PHE O CA 1 +ATOM 26908 C C . PHE O 1 35 ? 3.994 18.007 57.550 1.00 89.37 ? 35 PHE O C 1 +ATOM 26909 O O . PHE O 1 35 ? 3.652 17.566 56.445 1.00 110.79 ? 35 PHE O O 1 +ATOM 26910 C CB . PHE O 1 35 ? 3.848 15.876 58.821 1.00 107.48 ? 35 PHE O CB 1 +ATOM 26911 C CG . PHE O 1 35 ? 3.915 15.255 60.190 1.00 85.93 ? 35 PHE O CG 1 +ATOM 26912 C CD1 . PHE O 1 35 ? 4.585 15.884 61.225 1.00 81.72 ? 35 PHE O CD1 1 +ATOM 26913 C CD2 . PHE O 1 35 ? 3.415 13.980 60.394 1.00 84.28 ? 35 PHE O CD2 1 +ATOM 26914 C CE1 . PHE O 1 35 ? 4.677 15.294 62.467 1.00 79.35 ? 35 PHE O CE1 1 +ATOM 26915 C CE2 . PHE O 1 35 ? 3.525 13.373 61.623 1.00 88.21 ? 35 PHE O CE2 1 +ATOM 26916 C CZ . PHE O 1 35 ? 4.144 14.037 62.668 1.00 91.12 ? 35 PHE O CZ 1 +ATOM 26917 N N . VAL O 1 36 ? 4.936 18.932 57.690 1.00 67.07 ? 36 VAL O N 1 +ATOM 26918 C CA . VAL O 1 36 ? 5.466 19.611 56.521 1.00 80.59 ? 36 VAL O CA 1 +ATOM 26919 C C . VAL O 1 36 ? 7.006 19.636 56.472 1.00 115.40 ? 36 VAL O C 1 +ATOM 26920 O O . VAL O 1 36 ? 7.676 19.650 57.497 1.00 151.14 ? 36 VAL O O 1 +ATOM 26921 C CB . VAL O 1 36 ? 4.915 21.035 56.464 1.00 75.44 ? 36 VAL O CB 1 +ATOM 26922 C CG1 . VAL O 1 36 ? 5.606 21.911 57.496 1.00 94.03 ? 36 VAL O CG1 1 +ATOM 26923 C CG2 . VAL O 1 36 ? 5.079 21.603 55.074 1.00 67.36 ? 36 VAL O CG2 1 +ATOM 26924 N N . SER O 1 37 ? 7.556 19.688 55.263 1.00 121.66 ? 37 SER O N 1 +ATOM 26925 C CA . SER O 1 37 ? 8.998 19.769 55.080 1.00 104.86 ? 37 SER O CA 1 +ATOM 26926 C C . SER O 1 37 ? 9.333 21.008 54.283 1.00 112.93 ? 37 SER O C 1 +ATOM 26927 O O . SER O 1 37 ? 8.720 21.286 53.253 1.00 87.01 ? 37 SER O O 1 +ATOM 26928 C CB . SER O 1 37 ? 9.471 18.577 54.289 1.00 111.33 ? 37 SER O CB 1 +ATOM 26929 O OG . SER O 1 37 ? 9.471 17.405 55.064 1.00 145.59 ? 37 SER O OG 1 +ATOM 26930 N N . VAL O 1 38 ? 10.313 21.770 54.738 1.00 105.71 ? 38 VAL O N 1 +ATOM 26931 C CA . VAL O 1 38 ? 10.847 22.833 53.888 1.00 131.92 ? 38 VAL O CA 1 +ATOM 26932 C C . VAL O 1 38 ? 12.334 22.581 53.697 1.00 137.08 ? 38 VAL O C 1 +ATOM 26933 O O . VAL O 1 38 ? 13.093 22.628 54.679 1.00 220.41 ? 38 VAL O O 1 +ATOM 26934 C CB . VAL O 1 38 ? 10.657 24.253 54.489 1.00 140.17 ? 38 VAL O CB 1 +ATOM 26935 C CG1 . VAL O 1 38 ? 11.298 25.303 53.585 1.00 123.34 ? 38 VAL O CG1 1 +ATOM 26936 C CG2 . VAL O 1 38 ? 9.190 24.578 54.704 1.00 141.73 ? 38 VAL O CG2 1 +ATOM 26937 N N . TYR O 1 39 ? 12.748 22.396 52.440 1.00 90.85 ? 39 TYR O N 1 +ATOM 26938 C CA . TYR O 1 39 ? 14.140 22.154 52.114 1.00 71.99 ? 39 TYR O CA 1 +ATOM 26939 C C . TYR O 1 39 ? 14.857 23.495 51.869 1.00 72.87 ? 39 TYR O C 1 +ATOM 26940 O O . TYR O 1 39 ? 15.905 23.776 52.473 1.00 102.07 ? 39 TYR O O 1 +ATOM 26941 C CB . TYR O 1 39 ? 14.246 21.196 50.915 1.00 64.80 ? 39 TYR O CB 1 +ATOM 26942 C CG . TYR O 1 39 ? 14.159 19.724 51.307 1.00 64.17 ? 39 TYR O CG 1 +ATOM 26943 C CD1 . TYR O 1 39 ? 12.952 19.120 51.605 1.00 59.12 ? 39 TYR O CD1 1 +ATOM 26944 C CD2 . TYR O 1 39 ? 15.304 18.931 51.379 1.00 86.99 ? 39 TYR O CD2 1 +ATOM 26945 C CE1 . TYR O 1 39 ? 12.889 17.788 52.027 1.00 66.59 ? 39 TYR O CE1 1 +ATOM 26946 C CE2 . TYR O 1 39 ? 15.250 17.582 51.779 1.00 100.59 ? 39 TYR O CE2 1 +ATOM 26947 C CZ . TYR O 1 39 ? 14.040 17.010 52.128 1.00 71.66 ? 39 TYR O CZ 1 +ATOM 26948 O OH . TYR O 1 39 ? 14.002 15.661 52.489 1.00 37.40 ? 39 TYR O OH 1 +ATOM 26949 N N . ASN O 1 40 ? 14.307 24.337 51.004 1.00 73.45 ? 40 ASN O N 1 +ATOM 26950 C CA . ASN O 1 40 ? 14.964 25.601 50.669 1.00 77.81 ? 40 ASN O CA 1 +ATOM 26951 C C . ASN O 1 40 ? 14.090 26.558 49.880 1.00 83.54 ? 40 ASN O C 1 +ATOM 26952 O O . ASN O 1 40 ? 13.493 26.185 48.863 1.00 97.96 ? 40 ASN O O 1 +ATOM 26953 C CB . ASN O 1 40 ? 16.242 25.341 49.861 1.00 95.21 ? 40 ASN O CB 1 +ATOM 26954 C CG . ASN O 1 40 ? 17.181 26.532 49.865 1.00 106.63 ? 40 ASN O CG 1 +ATOM 26955 O OD1 . ASN O 1 40 ? 17.465 27.121 48.822 1.00 130.68 ? 40 ASN O OD1 1 +ATOM 26956 N ND2 . ASN O 1 40 ? 17.684 26.881 51.043 1.00 119.61 ? 40 ASN O ND2 1 +ATOM 26957 N N . ILE O 1 41 ? 14.072 27.816 50.304 1.00 80.32 ? 41 ILE O N 1 +ATOM 26958 C CA . ILE O 1 41 ? 13.488 28.901 49.503 1.00 92.15 ? 41 ILE O CA 1 +ATOM 26959 C C . ILE O 1 41 ? 14.573 29.918 49.112 1.00 81.89 ? 41 ILE O C 1 +ATOM 26960 O O . ILE O 1 41 ? 15.169 30.553 49.985 1.00 73.96 ? 41 ILE O O 1 +ATOM 26961 C CB . ILE O 1 41 ? 12.347 29.620 50.265 1.00 87.95 ? 41 ILE O CB 1 +ATOM 26962 C CG1 . ILE O 1 41 ? 11.051 28.822 50.206 1.00 94.11 ? 41 ILE O CG1 1 +ATOM 26963 C CG2 . ILE O 1 41 ? 12.056 30.959 49.621 1.00 88.07 ? 41 ILE O CG2 1 +ATOM 26964 C CD1 . ILE O 1 41 ? 11.040 27.532 51.013 1.00 93.66 ? 41 ILE O CD1 1 +ATOM 26965 N N . GLN O 1 42 ? 14.838 30.055 47.813 1.00 83.72 ? 42 GLN O N 1 +ATOM 26966 C CA . GLN O 1 42 ? 16.016 30.802 47.337 1.00 94.36 ? 42 GLN O CA 1 +ATOM 26967 C C . GLN O 1 42 ? 15.734 32.271 47.088 1.00 87.59 ? 42 GLN O C 1 +ATOM 26968 O O . GLN O 1 42 ? 14.586 32.675 46.903 1.00 75.35 ? 42 GLN O O 1 +ATOM 26969 C CB . GLN O 1 42 ? 16.545 30.228 46.029 1.00 121.01 ? 42 GLN O CB 1 +ATOM 26970 C CG . GLN O 1 42 ? 17.089 28.818 46.132 1.00 142.88 ? 42 GLN O CG 1 +ATOM 26971 C CD . GLN O 1 42 ? 16.327 27.837 45.256 1.00 164.97 ? 42 GLN O CD 1 +ATOM 26972 O OE1 . GLN O 1 42 ? 16.642 27.673 44.070 1.00 203.77 ? 42 GLN O OE1 1 +ATOM 26973 N NE2 . GLN O 1 42 ? 15.286 27.221 45.816 1.00 140.37 ? 42 GLN O NE2 1 +ATOM 26974 N N . ASP O 1 43 ? 16.802 33.063 47.106 1.00 83.31 ? 43 ASP O N 1 +ATOM 26975 C CA . ASP O 1 43 ? 16.741 34.484 46.751 1.00 74.91 ? 43 ASP O CA 1 +ATOM 26976 C C . ASP O 1 43 ? 16.815 34.623 45.266 1.00 56.27 ? 43 ASP O C 1 +ATOM 26977 O O . ASP O 1 43 ? 17.814 35.124 44.728 1.00 39.49 ? 43 ASP O O 1 +ATOM 26978 C CB . ASP O 1 43 ? 17.905 35.250 47.404 1.00 97.01 ? 43 ASP O CB 1 +ATOM 26979 C CG . ASP O 1 43 ? 17.789 36.764 47.216 1.00 124.05 ? 43 ASP O CG 1 +ATOM 26980 O OD1 . ASP O 1 43 ? 16.700 37.324 47.496 1.00 168.07 ? 43 ASP O OD1 1 +ATOM 26981 O OD2 . ASP O 1 43 ? 18.767 37.416 46.811 1.00 112.63 ? 43 ASP O OD2 1 +ATOM 26982 N N . GLU O 1 44 ? 15.783 34.111 44.593 1.00 57.40 ? 44 GLU O N 1 +ATOM 26983 C CA . GLU O 1 44 ? 15.752 34.084 43.124 1.00 75.49 ? 44 GLU O CA 1 +ATOM 26984 C C . GLU O 1 44 ? 15.627 35.523 42.513 1.00 78.71 ? 44 GLU O C 1 +ATOM 26985 O O . GLU O 1 44 ? 15.357 35.668 41.298 1.00 58.12 ? 44 GLU O O 1 +ATOM 26986 C CB . GLU O 1 44 ? 14.626 33.146 42.598 1.00 69.41 ? 44 GLU O CB 1 +ATOM 26987 C CG . GLU O 1 44 ? 15.024 31.671 42.424 1.00 88.31 ? 44 GLU O CG 1 +ATOM 26988 C CD . GLU O 1 44 ? 13.879 30.755 41.946 1.00 108.01 ? 44 GLU O CD 1 +ATOM 26989 O OE1 . GLU O 1 44 ? 13.133 31.098 40.998 1.00 139.97 ? 44 GLU O OE1 1 +ATOM 26990 O OE2 . GLU O 1 44 ? 13.743 29.638 42.478 1.00 111.82 ? 44 GLU O OE2 1 +ATOM 26991 N N . THR O 1 45 ? 15.930 36.547 43.330 1.00 77.33 ? 45 THR O N 1 +ATOM 26992 C CA . THR O 1 45 ? 15.627 37.945 42.997 1.00 69.20 ? 45 THR O CA 1 +ATOM 26993 C C . THR O 1 45 ? 16.636 38.588 42.064 1.00 74.60 ? 45 THR O C 1 +ATOM 26994 O O . THR O 1 45 ? 16.242 39.236 41.095 1.00 85.09 ? 45 THR O O 1 +ATOM 26995 C CB . THR O 1 45 ? 15.449 38.829 44.241 1.00 48.92 ? 45 THR O CB 1 +ATOM 26996 O OG1 . THR O 1 45 ? 14.861 40.064 43.839 1.00 76.04 ? 45 THR O OG1 1 +ATOM 26997 C CG2 . THR O 1 45 ? 16.735 39.101 44.916 1.00 43.41 ? 45 THR O CG2 1 +ATOM 26998 N N . GLY O 1 46 ? 17.905 38.276 42.256 1.00 91.32 ? 46 GLY O N 1 +ATOM 26999 C CA . GLY O 1 46 ? 18.937 38.628 41.264 1.00 120.05 ? 46 GLY O CA 1 +ATOM 27000 C C . GLY O 1 46 ? 19.487 40.013 41.533 1.00 118.59 ? 46 GLY O C 1 +ATOM 27001 O O . GLY O 1 46 ? 20.115 40.675 40.691 1.00 131.30 ? 46 GLY O O 1 +ATOM 27002 N N . GLN O 1 47 ? 19.310 40.456 42.747 1.00 102.16 ? 47 GLN O N 1 +ATOM 27003 C CA . GLN O 1 47 ? 19.475 41.827 42.961 1.00 109.26 ? 47 GLN O CA 1 +ATOM 27004 C C . GLN O 1 47 ? 20.378 42.116 44.148 1.00 132.55 ? 47 GLN O C 1 +ATOM 27005 O O . GLN O 1 47 ? 20.302 41.474 45.207 1.00 148.32 ? 47 GLN O O 1 +ATOM 27006 C CB . GLN O 1 47 ? 18.111 42.430 43.127 1.00 97.90 ? 47 GLN O CB 1 +ATOM 27007 C CG . GLN O 1 47 ? 17.307 42.413 41.845 1.00 80.20 ? 47 GLN O CG 1 +ATOM 27008 C CD . GLN O 1 47 ? 18.068 42.987 40.680 1.00 89.08 ? 47 GLN O CD 1 +ATOM 27009 O OE1 . GLN O 1 47 ? 18.291 44.191 40.589 1.00 66.32 ? 47 GLN O OE1 1 +ATOM 27010 N NE2 . GLN O 1 47 ? 18.453 42.135 39.765 1.00 125.71 ? 47 GLN O NE2 1 +ATOM 27011 N N . PHE O 1 48 ? 21.207 43.136 43.962 1.00 133.99 ? 48 PHE O N 1 +ATOM 27012 C CA . PHE O 1 48 ? 22.110 43.602 44.992 1.00 108.11 ? 48 PHE O CA 1 +ATOM 27013 C C . PHE O 1 48 ? 21.894 45.080 45.268 1.00 115.77 ? 48 PHE O C 1 +ATOM 27014 O O . PHE O 1 48 ? 21.289 45.821 44.478 1.00 103.05 ? 48 PHE O O 1 +ATOM 27015 C CB . PHE O 1 48 ? 23.562 43.351 44.556 1.00 117.10 ? 48 PHE O CB 1 +ATOM 27016 C CG . PHE O 1 48 ? 23.897 41.910 44.436 1.00 103.10 ? 48 PHE O CG 1 +ATOM 27017 C CD1 . PHE O 1 48 ? 23.449 41.186 43.354 1.00 87.84 ? 48 PHE O CD1 1 +ATOM 27018 C CD2 . PHE O 1 48 ? 24.547 41.268 45.455 1.00 94.69 ? 48 PHE O CD2 1 +ATOM 27019 C CE1 . PHE O 1 48 ? 23.631 39.842 43.295 1.00 86.19 ? 48 PHE O CE1 1 +ATOM 27020 C CE2 . PHE O 1 48 ? 24.729 39.918 45.411 1.00 96.45 ? 48 PHE O CE2 1 +ATOM 27021 C CZ . PHE O 1 48 ? 24.302 39.209 44.315 1.00 99.10 ? 48 PHE O CZ 1 +ATOM 27022 N N . LYS O 1 49 ? 22.495 45.528 46.363 1.00 145.66 ? 49 LYS O N 1 +ATOM 27023 C CA . LYS O 1 49 ? 22.388 46.920 46.779 1.00 127.00 ? 49 LYS O CA 1 +ATOM 27024 C C . LYS O 1 49 ? 23.296 47.786 45.923 1.00 114.33 ? 49 LYS O C 1 +ATOM 27025 O O . LYS O 1 49 ? 24.384 47.354 45.509 1.00 100.46 ? 49 LYS O O 1 +ATOM 27026 C CB . LYS O 1 49 ? 22.715 47.074 48.275 1.00 114.52 ? 49 LYS O CB 1 +ATOM 27027 C CG . LYS O 1 49 ? 21.695 46.360 49.159 1.00 113.31 ? 49 LYS O CG 1 +ATOM 27028 C CD . LYS O 1 49 ? 21.800 46.588 50.660 1.00 107.21 ? 49 LYS O CD 1 +ATOM 27029 C CE . LYS O 1 49 ? 20.605 45.886 51.320 1.00 99.07 ? 49 LYS O CE 1 +ATOM 27030 N NZ . LYS O 1 49 ? 20.541 45.984 52.811 1.00 85.35 ? 49 LYS O NZ 1 +ATOM 27031 N N . PRO O 1 50 ? 22.839 49.009 45.645 1.00 111.42 ? 50 PRO O N 1 +ATOM 27032 C CA . PRO O 1 50 ? 23.606 49.939 44.839 1.00 106.75 ? 50 PRO O CA 1 +ATOM 27033 C C . PRO O 1 50 ? 24.722 50.596 45.636 1.00 106.07 ? 50 PRO O C 1 +ATOM 27034 O O . PRO O 1 50 ? 24.753 50.531 46.893 1.00 119.97 ? 50 PRO O O 1 +ATOM 27035 C CB . PRO O 1 50 ? 22.558 50.970 44.406 1.00 118.59 ? 50 PRO O CB 1 +ATOM 27036 C CG . PRO O 1 50 ? 21.534 50.945 45.496 1.00 123.81 ? 50 PRO O CG 1 +ATOM 27037 C CD . PRO O 1 50 ? 21.507 49.534 46.009 1.00 111.58 ? 50 PRO O CD 1 +ATOM 27038 N N . TYR O 1 51 ? 25.628 51.241 44.913 1.00 109.75 ? 51 TYR O N 1 +ATOM 27039 C CA . TYR O 1 51 ? 26.609 52.092 45.549 1.00 114.88 ? 51 TYR O CA 1 +ATOM 27040 C C . TYR O 1 51 ? 25.919 53.021 46.565 1.00 117.10 ? 51 TYR O C 1 +ATOM 27041 O O . TYR O 1 51 ? 24.880 53.606 46.263 1.00 101.63 ? 51 TYR O O 1 +ATOM 27042 C CB . TYR O 1 51 ? 27.364 52.924 44.505 1.00 91.09 ? 51 TYR O CB 1 +ATOM 27043 C CG . TYR O 1 51 ? 28.613 53.522 45.075 1.00 109.79 ? 51 TYR O CG 1 +ATOM 27044 C CD1 . TYR O 1 51 ? 29.788 52.786 45.107 1.00 137.96 ? 51 TYR O CD1 1 +ATOM 27045 C CD2 . TYR O 1 51 ? 28.626 54.803 45.641 1.00 122.62 ? 51 TYR O CD2 1 +ATOM 27046 C CE1 . TYR O 1 51 ? 30.949 53.293 45.671 1.00 142.96 ? 51 TYR O CE1 1 +ATOM 27047 C CE2 . TYR O 1 51 ? 29.811 55.349 46.165 1.00 119.17 ? 51 TYR O CE2 1 +ATOM 27048 C CZ . TYR O 1 51 ? 30.959 54.563 46.201 1.00 132.49 ? 51 TYR O CZ 1 +ATOM 27049 O OH . TYR O 1 51 ? 32.145 55.009 46.731 1.00 121.57 ? 51 TYR O OH 1 +ATOM 27050 N N . PRO O 1 52 ? 26.496 53.171 47.775 1.00 126.05 ? 52 PRO O N 1 +ATOM 27051 C CA . PRO O 1 52 ? 27.816 52.701 48.233 1.00 116.98 ? 52 PRO O CA 1 +ATOM 27052 C C . PRO O 1 52 ? 27.879 51.345 48.933 1.00 82.18 ? 52 PRO O C 1 +ATOM 27053 O O . PRO O 1 52 ? 28.853 51.089 49.642 1.00 78.46 ? 52 PRO O O 1 +ATOM 27054 C CB . PRO O 1 52 ? 28.235 53.804 49.215 1.00 122.05 ? 52 PRO O CB 1 +ATOM 27055 C CG . PRO O 1 52 ? 26.940 54.239 49.831 1.00 125.38 ? 52 PRO O CG 1 +ATOM 27056 C CD . PRO O 1 52 ? 25.898 54.118 48.741 1.00 125.85 ? 52 PRO O CD 1 +ATOM 27057 N N . ALA O 1 53 ? 26.833 50.529 48.829 1.00 62.39 ? 53 ALA O N 1 +ATOM 27058 C CA . ALA O 1 53 ? 26.858 49.219 49.488 1.00 70.52 ? 53 ALA O CA 1 +ATOM 27059 C C . ALA O 1 53 ? 28.006 48.407 48.932 1.00 71.28 ? 53 ALA O C 1 +ATOM 27060 O O . ALA O 1 53 ? 28.509 48.685 47.807 1.00 67.42 ? 53 ALA O O 1 +ATOM 27061 C CB . ALA O 1 53 ? 25.542 48.472 49.295 1.00 84.87 ? 53 ALA O CB 1 +ATOM 27062 N N . SER O 1 54 ? 28.361 47.343 49.645 1.00 66.66 ? 54 SER O N 1 +ATOM 27063 C CA . SER O 1 54 ? 29.253 46.384 49.040 1.00 88.55 ? 54 SER O CA 1 +ATOM 27064 C C . SER O 1 54 ? 28.597 45.807 47.779 1.00 91.23 ? 54 SER O C 1 +ATOM 27065 O O . SER O 1 54 ? 27.395 45.561 47.723 1.00 53.94 ? 54 SER O O 1 +ATOM 27066 C CB . SER O 1 54 ? 29.635 45.260 49.992 1.00 110.64 ? 54 SER O CB 1 +ATOM 27067 O OG . SER O 1 54 ? 30.108 44.096 49.302 1.00 167.70 ? 54 SER O OG 1 +ATOM 27068 N N . ASN O 1 55 ? 29.425 45.630 46.747 1.00 86.68 ? 55 ASN O N 1 +ATOM 27069 C CA . ASN O 1 55 ? 29.011 45.002 45.519 1.00 68.10 ? 55 ASN O CA 1 +ATOM 27070 C C . ASN O 1 55 ? 28.236 43.696 45.790 1.00 76.84 ? 55 ASN O C 1 +ATOM 27071 O O . ASN O 1 55 ? 27.342 43.293 45.013 1.00 82.71 ? 55 ASN O O 1 +ATOM 27072 C CB . ASN O 1 55 ? 30.234 44.713 44.679 1.00 55.85 ? 55 ASN O CB 1 +ATOM 27073 C CG . ASN O 1 55 ? 29.890 44.444 43.247 1.00 81.41 ? 55 ASN O CG 1 +ATOM 27074 O OD1 . ASN O 1 55 ? 28.809 44.755 42.760 1.00 113.18 ? 55 ASN O OD1 1 +ATOM 27075 N ND2 . ASN O 1 55 ? 30.828 43.874 42.551 1.00 107.85 ? 55 ASN O ND2 1 +ATOM 27076 N N . PHE O 1 56 ? 28.574 43.040 46.911 1.00 61.78 ? 56 PHE O N 1 +ATOM 27077 C CA . PHE O 1 56 ? 28.095 41.684 47.222 1.00 55.64 ? 56 PHE O CA 1 +ATOM 27078 C C . PHE O 1 56 ? 26.909 41.714 48.154 1.00 60.72 ? 56 PHE O C 1 +ATOM 27079 O O . PHE O 1 56 ? 26.430 40.649 48.567 1.00 60.96 ? 56 PHE O O 1 +ATOM 27080 C CB . PHE O 1 56 ? 29.176 40.843 47.880 1.00 49.06 ? 56 PHE O CB 1 +ATOM 27081 C CG . PHE O 1 56 ? 30.384 40.688 47.041 1.00 73.64 ? 56 PHE O CG 1 +ATOM 27082 C CD1 . PHE O 1 56 ? 30.337 40.113 45.768 1.00 79.18 ? 56 PHE O CD1 1 +ATOM 27083 C CD2 . PHE O 1 56 ? 31.566 41.253 47.451 1.00 120.81 ? 56 PHE O CD2 1 +ATOM 27084 C CE1 . PHE O 1 56 ? 31.450 40.109 44.926 1.00 77.44 ? 56 PHE O CE1 1 +ATOM 27085 C CE2 . PHE O 1 56 ? 32.703 41.181 46.642 1.00 139.75 ? 56 PHE O CE2 1 +ATOM 27086 C CZ . PHE O 1 56 ? 32.637 40.631 45.361 1.00 89.27 ? 56 PHE O CZ 1 +ATOM 27087 N N . SER O 1 57 ? 26.477 42.899 48.579 1.00 52.30 ? 57 SER O N 1 +ATOM 27088 C CA . SER O 1 57 ? 25.362 42.946 49.498 1.00 51.33 ? 57 SER O CA 1 +ATOM 27089 C C . SER O 1 57 ? 24.087 42.668 48.697 1.00 50.17 ? 57 SER O C 1 +ATOM 27090 O O . SER O 1 57 ? 23.672 43.456 47.845 1.00 53.53 ? 57 SER O O 1 +ATOM 27091 C CB . SER O 1 57 ? 25.320 44.292 50.221 1.00 59.57 ? 57 SER O CB 1 +ATOM 27092 O OG . SER O 1 57 ? 26.307 44.345 51.227 1.00 77.15 ? 57 SER O OG 1 +ATOM 27093 N N . THR O 1 58 ? 23.432 41.570 49.010 1.00 55.55 ? 58 THR O N 1 +ATOM 27094 C CA . THR O 1 58 ? 22.170 41.252 48.371 1.00 77.71 ? 58 THR O CA 1 +ATOM 27095 C C . THR O 1 58 ? 21.076 42.226 48.771 1.00 101.65 ? 58 THR O C 1 +ATOM 27096 O O . THR O 1 58 ? 21.002 42.718 49.893 1.00 113.47 ? 58 THR O O 1 +ATOM 27097 C CB . THR O 1 58 ? 21.706 39.846 48.758 1.00 71.07 ? 58 THR O CB 1 +ATOM 27098 O OG1 . THR O 1 58 ? 21.486 39.790 50.182 1.00 49.41 ? 58 THR O OG1 1 +ATOM 27099 C CG2 . THR O 1 58 ? 22.762 38.892 48.393 1.00 82.38 ? 58 THR O CG2 1 +ATOM 27100 N N . ALA O 1 59 ? 20.125 42.412 47.898 1.00 100.48 ? 59 ALA O N 1 +ATOM 27101 C CA . ALA O 1 59 ? 19.059 43.306 48.259 1.00 100.33 ? 59 ALA O CA 1 +ATOM 27102 C C . ALA O 1 59 ? 18.099 42.712 49.312 1.00 70.51 ? 59 ALA O C 1 +ATOM 27103 O O . ALA O 1 59 ? 17.308 43.429 49.906 1.00 69.77 ? 59 ALA O O 1 +ATOM 27104 C CB . ALA O 1 59 ? 18.324 43.739 47.002 1.00 119.13 ? 59 ALA O CB 1 +ATOM 27105 N N . VAL O 1 60 ? 18.082 41.394 49.415 1.00 58.92 ? 60 VAL O N 1 +ATOM 27106 C CA . VAL O 1 60 ? 17.066 40.685 50.162 1.00 55.79 ? 60 VAL O CA 1 +ATOM 27107 C C . VAL O 1 60 ? 17.769 39.668 50.994 1.00 70.29 ? 60 VAL O C 1 +ATOM 27108 O O . VAL O 1 60 ? 18.741 39.014 50.538 1.00 88.29 ? 60 VAL O O 1 +ATOM 27109 C CB . VAL O 1 60 ? 16.112 39.933 49.209 1.00 78.55 ? 60 VAL O CB 1 +ATOM 27110 C CG1 . VAL O 1 60 ? 15.072 39.122 49.972 1.00 77.60 ? 60 VAL O CG1 1 +ATOM 27111 C CG2 . VAL O 1 60 ? 15.417 40.912 48.257 1.00 114.54 ? 60 VAL O CG2 1 +ATOM 27112 N N . PRO O 1 61 ? 17.289 39.473 52.212 1.00 84.58 ? 61 PRO O N 1 +ATOM 27113 C CA . PRO O 1 61 ? 18.000 38.513 53.080 1.00 114.76 ? 61 PRO O CA 1 +ATOM 27114 C C . PRO O 1 61 ? 17.845 37.075 52.611 1.00 98.75 ? 61 PRO O C 1 +ATOM 27115 O O . PRO O 1 61 ? 16.795 36.724 52.050 1.00 72.71 ? 61 PRO O O 1 +ATOM 27116 C CB . PRO O 1 61 ? 17.316 38.695 54.441 1.00 143.10 ? 61 PRO O CB 1 +ATOM 27117 C CG . PRO O 1 61 ? 15.998 39.340 54.123 1.00 124.50 ? 61 PRO O CG 1 +ATOM 27118 C CD . PRO O 1 61 ? 16.271 40.230 52.944 1.00 86.89 ? 61 PRO O CD 1 +ATOM 27119 N N . GLN O 1 62 ? 18.880 36.266 52.847 1.00 85.41 ? 62 GLN O N 1 +ATOM 27120 C CA . GLN O 1 62 ? 18.943 34.913 52.292 1.00 95.09 ? 62 GLN O CA 1 +ATOM 27121 C C . GLN O 1 62 ? 18.298 33.945 53.248 1.00 84.42 ? 62 GLN O C 1 +ATOM 27122 O O . GLN O 1 62 ? 18.759 32.823 53.384 1.00 161.50 ? 62 GLN O O 1 +ATOM 27123 C CB . GLN O 1 62 ? 20.413 34.479 52.024 1.00 85.37 ? 62 GLN O CB 1 +ATOM 27124 C CG . GLN O 1 62 ? 21.220 35.455 51.191 1.00 75.47 ? 62 GLN O CG 1 +ATOM 27125 C CD . GLN O 1 62 ? 20.571 35.710 49.841 1.00 73.54 ? 62 GLN O CD 1 +ATOM 27126 O OE1 . GLN O 1 62 ? 20.678 34.897 48.940 1.00 75.37 ? 62 GLN O OE1 1 +ATOM 27127 N NE2 . GLN O 1 62 ? 19.889 36.840 49.705 1.00 64.15 ? 62 GLN O NE2 1 +ATOM 27128 N N . SER O 1 63 ? 17.261 34.383 53.932 1.00 66.05 ? 63 SER O N 1 +ATOM 27129 C CA . SER O 1 63 ? 16.825 33.723 55.147 1.00 85.85 ? 63 SER O CA 1 +ATOM 27130 C C . SER O 1 63 ? 15.392 33.212 55.045 1.00 85.63 ? 63 SER O C 1 +ATOM 27131 O O . SER O 1 63 ? 14.771 32.839 56.040 1.00 108.87 ? 63 SER O O 1 +ATOM 27132 C CB . SER O 1 63 ? 17.018 34.681 56.360 1.00 111.19 ? 63 SER O CB 1 +ATOM 27133 O OG . SER O 1 63 ? 16.255 35.875 56.276 1.00 118.90 ? 63 SER O OG 1 +ATOM 27134 N N . ALA O 1 64 ? 14.840 33.307 53.848 1.00 91.36 ? 64 ALA O N 1 +ATOM 27135 C CA . ALA O 1 64 ? 13.408 33.100 53.626 1.00 86.58 ? 64 ALA O CA 1 +ATOM 27136 C C . ALA O 1 64 ? 12.953 31.731 54.123 1.00 80.07 ? 64 ALA O C 1 +ATOM 27137 O O . ALA O 1 64 ? 11.855 31.564 54.656 1.00 48.99 ? 64 ALA O O 1 +ATOM 27138 C CB . ALA O 1 64 ? 13.119 33.262 52.144 1.00 93.25 ? 64 ALA O CB 1 +ATOM 27139 N N . THR O 1 65 ? 13.839 30.751 53.962 1.00 115.40 ? 65 THR O N 1 +ATOM 27140 C CA . THR O 1 65 ? 13.559 29.371 54.333 1.00 125.41 ? 65 THR O CA 1 +ATOM 27141 C C . THR O 1 65 ? 13.107 29.294 55.780 1.00 121.20 ? 65 THR O C 1 +ATOM 27142 O O . THR O 1 65 ? 12.111 28.640 56.107 1.00 98.25 ? 65 THR O O 1 +ATOM 27143 C CB . THR O 1 65 ? 14.830 28.520 54.168 1.00 100.84 ? 65 THR O CB 1 +ATOM 27144 O OG1 . THR O 1 65 ? 15.492 28.920 52.965 1.00 80.43 ? 65 THR O OG1 1 +ATOM 27145 C CG2 . THR O 1 65 ? 14.472 27.031 54.108 1.00 113.98 ? 65 THR O CG2 1 +ATOM 27146 N N . ALA O 1 66 ? 13.880 29.925 56.650 1.00 124.49 ? 66 ALA O N 1 +ATOM 27147 C CA . ALA O 1 66 ? 13.644 29.803 58.073 1.00 129.92 ? 66 ALA O CA 1 +ATOM 27148 C C . ALA O 1 66 ? 12.396 30.571 58.461 1.00 83.48 ? 66 ALA O C 1 +ATOM 27149 O O . ALA O 1 66 ? 11.649 30.154 59.349 1.00 80.04 ? 66 ALA O O 1 +ATOM 27150 C CB . ALA O 1 66 ? 14.862 30.288 58.842 1.00 157.76 ? 66 ALA O CB 1 +ATOM 27151 N N . MET O 1 67 ? 12.153 31.658 57.744 1.00 83.59 ? 67 MET O N 1 +ATOM 27152 C CA . MET O 1 67 ? 10.964 32.464 57.973 1.00 106.52 ? 67 MET O CA 1 +ATOM 27153 C C . MET O 1 67 ? 9.719 31.648 57.630 1.00 119.65 ? 67 MET O C 1 +ATOM 27154 O O . MET O 1 67 ? 8.701 31.692 58.351 1.00 150.68 ? 67 MET O O 1 +ATOM 27155 C CB . MET O 1 67 ? 10.985 33.749 57.128 1.00 95.49 ? 67 MET O CB 1 +ATOM 27156 C CG . MET O 1 67 ? 11.995 34.803 57.555 1.00 90.89 ? 67 MET O CG 1 +ATOM 27157 S SD . MET O 1 67 ? 12.167 36.106 56.310 1.00 82.69 ? 67 MET O SD 1 +ATOM 27158 C CE . MET O 1 67 ? 13.245 37.257 57.142 1.00 106.21 ? 67 MET O CE 1 +ATOM 27159 N N . LEU O 1 68 ? 9.801 30.897 56.537 1.00 95.73 ? 68 LEU O N 1 +ATOM 27160 C CA . LEU O 1 68 ? 8.661 30.110 56.111 1.00 94.99 ? 68 LEU O CA 1 +ATOM 27161 C C . LEU O 1 68 ? 8.396 29.018 57.117 1.00 90.37 ? 68 LEU O C 1 +ATOM 27162 O O . LEU O 1 68 ? 7.235 28.761 57.456 1.00 107.47 ? 68 LEU O O 1 +ATOM 27163 C CB . LEU O 1 68 ? 8.884 29.484 54.738 1.00 94.83 ? 68 LEU O CB 1 +ATOM 27164 C CG . LEU O 1 68 ? 7.812 28.432 54.372 1.00 76.21 ? 68 LEU O CG 1 +ATOM 27165 C CD1 . LEU O 1 68 ? 6.455 29.060 54.181 1.00 64.70 ? 68 LEU O CD1 1 +ATOM 27166 C CD2 . LEU O 1 68 ? 8.201 27.654 53.127 1.00 87.98 ? 68 LEU O CD2 1 +ATOM 27167 N N . VAL O 1 69 ? 9.452 28.351 57.575 1.00 90.75 ? 69 VAL O N 1 +ATOM 27168 C CA . VAL O 1 69 ? 9.285 27.260 58.551 1.00 126.63 ? 69 VAL O CA 1 +ATOM 27169 C C . VAL O 1 69 ? 8.648 27.799 59.838 1.00 116.48 ? 69 VAL O C 1 +ATOM 27170 O O . VAL O 1 69 ? 7.714 27.213 60.382 1.00 115.81 ? 69 VAL O O 1 +ATOM 27171 C CB . VAL O 1 69 ? 10.621 26.588 58.922 1.00 156.39 ? 69 VAL O CB 1 +ATOM 27172 C CG1 . VAL O 1 69 ? 10.407 25.612 60.068 1.00 164.41 ? 69 VAL O CG1 1 +ATOM 27173 C CG2 . VAL O 1 69 ? 11.232 25.855 57.737 1.00 161.81 ? 69 VAL O CG2 1 +ATOM 27174 N N . THR O 1 70 ? 9.117 28.960 60.270 1.00 123.38 ? 70 THR O N 1 +ATOM 27175 C CA . THR O 1 70 ? 8.570 29.621 61.448 1.00 135.12 ? 70 THR O CA 1 +ATOM 27176 C C . THR O 1 70 ? 7.098 30.002 61.265 1.00 140.66 ? 70 THR O C 1 +ATOM 27177 O O . THR O 1 70 ? 6.270 29.758 62.144 1.00 138.68 ? 70 THR O O 1 +ATOM 27178 C CB . THR O 1 70 ? 9.391 30.877 61.788 1.00 153.48 ? 70 THR O CB 1 +ATOM 27179 O OG1 . THR O 1 70 ? 10.770 30.497 61.909 1.00 202.89 ? 70 THR O OG1 1 +ATOM 27180 C CG2 . THR O 1 70 ? 8.895 31.520 63.095 1.00 132.19 ? 70 THR O CG2 1 +ATOM 27181 N N . ALA O 1 71 ? 6.769 30.573 60.106 1.00 128.21 ? 71 ALA O N 1 +ATOM 27182 C CA . ALA O 1 71 ? 5.381 30.917 59.803 1.00 124.98 ? 71 ALA O CA 1 +ATOM 27183 C C . ALA O 1 71 ? 4.487 29.667 59.779 1.00 128.74 ? 71 ALA O C 1 +ATOM 27184 O O . ALA O 1 71 ? 3.365 29.669 60.311 1.00 154.91 ? 71 ALA O O 1 +ATOM 27185 C CB . ALA O 1 71 ? 5.293 31.655 58.473 1.00 107.33 ? 71 ALA O CB 1 +ATOM 27186 N N . LEU O 1 72 ? 4.990 28.596 59.170 1.00 105.83 ? 72 LEU O N 1 +ATOM 27187 C CA . LEU O 1 72 ? 4.264 27.322 59.148 1.00 87.43 ? 72 LEU O CA 1 +ATOM 27188 C C . LEU O 1 72 ? 4.007 26.789 60.561 1.00 107.64 ? 72 LEU O C 1 +ATOM 27189 O O . LEU O 1 72 ? 3.044 26.052 60.774 1.00 108.30 ? 72 LEU O O 1 +ATOM 27190 C CB . LEU O 1 72 ? 5.019 26.271 58.336 1.00 61.58 ? 72 LEU O CB 1 +ATOM 27191 C CG . LEU O 1 72 ? 5.121 26.561 56.849 1.00 56.25 ? 72 LEU O CG 1 +ATOM 27192 C CD1 . LEU O 1 72 ? 6.200 25.710 56.255 1.00 55.07 ? 72 LEU O CD1 1 +ATOM 27193 C CD2 . LEU O 1 72 ? 3.815 26.277 56.144 1.00 87.32 ? 72 LEU O CD2 1 +ATOM 27194 N N . LYS O 1 73 ? 4.874 27.148 61.514 1.00 115.37 ? 73 LYS O N 1 +ATOM 27195 C CA . LYS O 1 73 ? 4.711 26.683 62.895 1.00 111.21 ? 73 LYS O CA 1 +ATOM 27196 C C . LYS O 1 73 ? 3.762 27.556 63.668 1.00 111.64 ? 73 LYS O C 1 +ATOM 27197 O O . LYS O 1 73 ? 2.871 27.057 64.348 1.00 105.51 ? 73 LYS O O 1 +ATOM 27198 C CB . LYS O 1 73 ? 6.038 26.632 63.633 1.00 110.00 ? 73 LYS O CB 1 +ATOM 27199 C CG . LYS O 1 73 ? 5.956 25.879 64.959 1.00 127.08 ? 73 LYS O CG 1 +ATOM 27200 C CD . LYS O 1 73 ? 7.309 25.851 65.672 1.00 177.33 ? 73 LYS O CD 1 +ATOM 27201 C CE . LYS O 1 73 ? 7.158 25.748 67.182 1.00 201.73 ? 73 LYS O CE 1 +ATOM 27202 N NZ . LYS O 1 73 ? 7.663 24.458 67.733 1.00 215.92 ? 73 LYS O NZ 1 +ATOM 27203 N N . ASP O 1 74 ? 3.929 28.865 63.527 1.00 113.44 ? 74 ASP O N 1 +ATOM 27204 C CA . ASP O 1 74 ? 3.091 29.812 64.246 1.00 132.73 ? 74 ASP O CA 1 +ATOM 27205 C C . ASP O 1 74 ? 1.605 29.654 63.915 1.00 140.82 ? 74 ASP O C 1 +ATOM 27206 O O . ASP O 1 74 ? 0.738 29.961 64.750 1.00 170.46 ? 74 ASP O O 1 +ATOM 27207 C CB . ASP O 1 74 ? 3.543 31.247 63.960 1.00 134.07 ? 74 ASP O CB 1 +ATOM 27208 C CG . ASP O 1 74 ? 4.935 31.551 64.523 1.00 126.17 ? 74 ASP O CG 1 +ATOM 27209 O OD1 . ASP O 1 74 ? 5.317 30.990 65.586 1.00 117.05 ? 74 ASP O OD1 1 +ATOM 27210 O OD2 . ASP O 1 74 ? 5.584 32.470 63.969 1.00 101.81 ? 74 ASP O OD2 1 +ATOM 27211 N N . SER O 1 75 ? 1.313 29.188 62.700 1.00 137.30 ? 75 SER O N 1 +ATOM 27212 C CA . SER O 1 75 ? -0.069 29.051 62.220 1.00 147.27 ? 75 SER O CA 1 +ATOM 27213 C C . SER O 1 75 ? -0.866 28.012 63.018 1.00 140.66 ? 75 SER O C 1 +ATOM 27214 O O . SER O 1 75 ? -2.099 28.081 63.061 1.00 119.01 ? 75 SER O O 1 +ATOM 27215 C CB . SER O 1 75 ? -0.094 28.664 60.737 1.00 142.70 ? 75 SER O CB 1 +ATOM 27216 O OG . SER O 1 75 ? 0.018 27.260 60.577 1.00 124.18 ? 75 SER O OG 1 +ATOM 27217 N N . ARG O 1 76 ? -0.148 27.062 63.622 1.00 119.54 ? 76 ARG O N 1 +ATOM 27218 C CA . ARG O 1 76 ? -0.733 25.956 64.382 1.00 122.33 ? 76 ARG O CA 1 +ATOM 27219 C C . ARG O 1 76 ? -1.570 25.062 63.496 1.00 108.63 ? 76 ARG O C 1 +ATOM 27220 O O . ARG O 1 76 ? -2.615 24.566 63.890 1.00 78.00 ? 76 ARG O O 1 +ATOM 27221 C CB . ARG O 1 76 ? -1.550 26.472 65.554 1.00 151.55 ? 76 ARG O CB 1 +ATOM 27222 C CG . ARG O 1 76 ? -0.757 27.270 66.581 1.00 171.92 ? 76 ARG O CG 1 +ATOM 27223 C CD . ARG O 1 76 ? -1.666 27.702 67.729 1.00 213.51 ? 76 ARG O CD 1 +ATOM 27224 N NE . ARG O 1 76 ? -2.642 28.717 67.304 1.00 227.13 ? 76 ARG O NE 1 +ATOM 27225 C CZ . ARG O 1 76 ? -3.889 28.469 66.894 1.00 199.38 ? 76 ARG O CZ 1 +ATOM 27226 N NH1 . ARG O 1 76 ? -4.364 27.225 66.840 1.00 210.07 ? 76 ARG O NH1 1 +ATOM 27227 N NH2 . ARG O 1 76 ? -4.661 29.475 66.522 1.00 155.65 ? 76 ARG O NH2 1 +ATOM 27228 N N . TRP O 1 77 ? -1.123 24.935 62.257 1.00 130.48 ? 77 TRP O N 1 +ATOM 27229 C CA . TRP O 1 77 ? -1.695 23.989 61.312 1.00 128.18 ? 77 TRP O CA 1 +ATOM 27230 C C . TRP O 1 77 ? -0.681 22.894 60.978 1.00 158.31 ? 77 TRP O C 1 +ATOM 27231 O O . TRP O 1 77 ? -1.050 21.742 60.724 1.00 166.82 ? 77 TRP O O 1 +ATOM 27232 C CB . TRP O 1 77 ? -2.102 24.724 60.026 1.00 117.80 ? 77 TRP O CB 1 +ATOM 27233 C CG . TRP O 1 77 ? -3.514 25.192 60.011 1.00 113.51 ? 77 TRP O CG 1 +ATOM 27234 C CD1 . TRP O 1 77 ? -4.018 26.271 60.653 1.00 116.22 ? 77 TRP O CD1 1 +ATOM 27235 C CD2 . TRP O 1 77 ? -4.603 24.612 59.284 1.00 112.50 ? 77 TRP O CD2 1 +ATOM 27236 N NE1 . TRP O 1 77 ? -5.358 26.388 60.394 1.00 125.13 ? 77 TRP O NE1 1 +ATOM 27237 C CE2 . TRP O 1 77 ? -5.738 25.377 59.554 1.00 109.43 ? 77 TRP O CE2 1 +ATOM 27238 C CE3 . TRP O 1 77 ? -4.725 23.509 58.442 1.00 134.61 ? 77 TRP O CE3 1 +ATOM 27239 C CZ2 . TRP O 1 77 ? -6.982 25.080 59.010 1.00 111.69 ? 77 TRP O CZ2 1 +ATOM 27240 C CZ3 . TRP O 1 77 ? -5.966 23.216 57.903 1.00 119.88 ? 77 TRP O CZ3 1 +ATOM 27241 C CH2 . TRP O 1 77 ? -7.073 24.006 58.180 1.00 105.97 ? 77 TRP O CH2 1 +ATOM 27242 N N . PHE O 1 78 ? 0.599 23.274 60.954 1.00 188.27 ? 78 PHE O N 1 +ATOM 27243 C CA . PHE O 1 78 ? 1.691 22.404 60.498 1.00 157.47 ? 78 PHE O CA 1 +ATOM 27244 C C . PHE O 1 78 ? 2.750 22.158 61.584 1.00 126.71 ? 78 PHE O C 1 +ATOM 27245 O O . PHE O 1 78 ? 3.092 23.071 62.343 1.00 135.66 ? 78 PHE O O 1 +ATOM 27246 C CB . PHE O 1 78 ? 2.399 23.045 59.309 1.00 128.07 ? 78 PHE O CB 1 +ATOM 27247 C CG . PHE O 1 78 ? 1.490 23.395 58.179 1.00 110.45 ? 78 PHE O CG 1 +ATOM 27248 C CD1 . PHE O 1 78 ? 0.968 22.410 57.350 1.00 113.94 ? 78 PHE O CD1 1 +ATOM 27249 C CD2 . PHE O 1 78 ? 1.154 24.705 57.947 1.00 101.71 ? 78 PHE O CD2 1 +ATOM 27250 C CE1 . PHE O 1 78 ? 0.130 22.732 56.299 1.00 110.49 ? 78 PHE O CE1 1 +ATOM 27251 C CE2 . PHE O 1 78 ? 0.344 25.041 56.881 1.00 106.77 ? 78 PHE O CE2 1 +ATOM 27252 C CZ . PHE O 1 78 ? -0.167 24.054 56.054 1.00 107.15 ? 78 PHE O CZ 1 +ATOM 27253 N N . ILE O 1 79 ? 3.270 20.935 61.623 1.00 86.32 ? 79 ILE O N 1 +ATOM 27254 C CA . ILE O 1 79 ? 4.493 20.624 62.319 1.00 84.13 ? 79 ILE O CA 1 +ATOM 27255 C C . ILE O 1 79 ? 5.582 20.639 61.260 1.00 102.28 ? 79 ILE O C 1 +ATOM 27256 O O . ILE O 1 79 ? 5.483 19.930 60.248 1.00 107.63 ? 79 ILE O O 1 +ATOM 27257 C CB . ILE O 1 79 ? 4.436 19.222 62.925 1.00 101.58 ? 79 ILE O CB 1 +ATOM 27258 C CG1 . ILE O 1 79 ? 3.151 19.023 63.723 1.00 112.87 ? 79 ILE O CG1 1 +ATOM 27259 C CG2 . ILE O 1 79 ? 5.646 18.973 63.822 1.00 121.75 ? 79 ILE O CG2 1 +ATOM 27260 C CD1 . ILE O 1 79 ? 2.748 17.569 63.883 1.00 129.37 ? 79 ILE O CD1 1 +ATOM 27261 N N . PRO O 1 80 ? 6.626 21.456 61.466 1.00 115.10 ? 80 PRO O N 1 +ATOM 27262 C CA . PRO O 1 80 ? 7.692 21.425 60.467 1.00 114.69 ? 80 PRO O CA 1 +ATOM 27263 C C . PRO O 1 80 ? 8.772 20.428 60.838 1.00 126.75 ? 80 PRO O C 1 +ATOM 27264 O O . PRO O 1 80 ? 9.141 20.330 62.005 1.00 107.96 ? 80 PRO O O 1 +ATOM 27265 C CB . PRO O 1 80 ? 8.250 22.838 60.498 1.00 84.98 ? 80 PRO O CB 1 +ATOM 27266 C CG . PRO O 1 80 ? 7.155 23.649 61.056 1.00 109.91 ? 80 PRO O CG 1 +ATOM 27267 C CD . PRO O 1 80 ? 6.563 22.763 62.119 1.00 112.93 ? 80 PRO O CD 1 +ATOM 27268 N N . LEU O 1 81 ? 9.159 19.611 59.869 1.00 114.58 ? 81 LEU O N 1 +ATOM 27269 C CA . LEU O 1 81 ? 10.220 18.674 60.059 1.00 93.48 ? 81 LEU O CA 1 +ATOM 27270 C C . LEU O 1 81 ? 11.485 19.316 59.544 1.00 91.86 ? 81 LEU O C 1 +ATOM 27271 O O . LEU O 1 81 ? 11.467 20.062 58.550 1.00 102.40 ? 81 LEU O O 1 +ATOM 27272 C CB . LEU O 1 81 ? 9.910 17.395 59.317 1.00 107.16 ? 81 LEU O CB 1 +ATOM 27273 C CG . LEU O 1 81 ? 8.572 16.810 59.751 1.00 131.43 ? 81 LEU O CG 1 +ATOM 27274 C CD1 . LEU O 1 81 ? 8.272 15.602 58.901 1.00 120.49 ? 81 LEU O CD1 1 +ATOM 27275 C CD2 . LEU O 1 81 ? 8.608 16.426 61.223 1.00 155.23 ? 81 LEU O CD2 1 +ATOM 27276 N N . GLU O 1 82 ? 12.560 19.093 60.289 1.00 71.98 ? 82 GLU O N 1 +ATOM 27277 C CA . GLU O 1 82 ? 13.845 19.739 60.012 1.00 60.76 ? 82 GLU O CA 1 +ATOM 27278 C C . GLU O 1 82 ? 14.522 19.023 58.849 1.00 53.07 ? 82 GLU O C 1 +ATOM 27279 O O . GLU O 1 82 ? 15.041 17.908 58.997 1.00 55.67 ? 82 GLU O O 1 +ATOM 27280 C CB . GLU O 1 82 ? 14.766 19.757 61.280 1.00 66.67 ? 82 GLU O CB 1 +ATOM 27281 C CG . GLU O 1 82 ? 16.161 20.373 61.096 1.00 56.08 ? 82 GLU O CG 1 +ATOM 27282 C CD . GLU O 1 82 ? 16.151 21.892 60.842 1.00 83.22 ? 82 GLU O CD 1 +ATOM 27283 O OE1 . GLU O 1 82 ? 15.322 22.440 60.012 1.00 77.65 ? 82 GLU O OE1 1 +ATOM 27284 O OE2 . GLU O 1 82 ? 16.960 22.583 61.518 1.00 94.84 ? 82 GLU O OE2 1 +ATOM 27285 N N . ARG O 1 83 ? 14.625 19.739 57.750 1.00 55.18 ? 83 ARG O N 1 +ATOM 27286 C CA . ARG O 1 83 ? 15.406 19.303 56.605 1.00 54.29 ? 83 ARG O CA 1 +ATOM 27287 C C . ARG O 1 83 ? 16.453 20.351 56.163 1.00 78.20 ? 83 ARG O C 1 +ATOM 27288 O O . ARG O 1 83 ? 17.409 20.006 55.483 1.00 96.55 ? 83 ARG O O 1 +ATOM 27289 C CB . ARG O 1 83 ? 14.474 19.011 55.453 1.00 58.07 ? 83 ARG O CB 1 +ATOM 27290 C CG . ARG O 1 83 ? 13.399 17.998 55.781 1.00 66.81 ? 83 ARG O CG 1 +ATOM 27291 C CD . ARG O 1 83 ? 13.943 16.613 55.964 1.00 68.96 ? 83 ARG O CD 1 +ATOM 27292 N NE . ARG O 1 83 ? 12.822 15.662 56.031 1.00 85.58 ? 83 ARG O NE 1 +ATOM 27293 C CZ . ARG O 1 83 ? 12.337 15.093 57.141 1.00 77.92 ? 83 ARG O CZ 1 +ATOM 27294 N NH1 . ARG O 1 83 ? 12.892 15.337 58.331 1.00 65.45 ? 83 ARG O NH1 1 +ATOM 27295 N NH2 . ARG O 1 83 ? 11.291 14.276 57.046 1.00 64.95 ? 83 ARG O NH2 1 +ATOM 27296 N N . GLN O 1 84 ? 16.324 21.622 56.564 1.00 119.65 ? 84 GLN O N 1 +ATOM 27297 C CA . GLN O 1 84 ? 17.361 22.611 56.207 1.00 116.38 ? 84 GLN O CA 1 +ATOM 27298 C C . GLN O 1 84 ? 18.744 22.172 56.732 1.00 121.37 ? 84 GLN O C 1 +ATOM 27299 O O . GLN O 1 84 ? 19.725 22.234 56.022 1.00 193.39 ? 84 GLN O O 1 +ATOM 27300 C CB . GLN O 1 84 ? 17.026 24.034 56.693 1.00 128.96 ? 84 GLN O CB 1 +ATOM 27301 C CG . GLN O 1 84 ? 17.560 25.156 55.795 1.00 130.92 ? 84 GLN O CG 1 +ATOM 27302 C CD . GLN O 1 84 ? 17.290 26.561 56.338 1.00 146.06 ? 84 GLN O CD 1 +ATOM 27303 O OE1 . GLN O 1 84 ? 16.277 26.799 56.985 1.00 158.40 ? 84 GLN O OE1 1 +ATOM 27304 N NE2 . GLN O 1 84 ? 18.250 27.473 56.146 1.00 135.69 ? 84 GLN O NE2 1 +ATOM 27305 N N . GLY O 1 85 ? 18.822 21.661 57.947 1.00 88.94 ? 85 GLY O N 1 +ATOM 27306 C CA . GLY O 1 85 ? 20.104 21.158 58.430 1.00 76.56 ? 85 GLY O CA 1 +ATOM 27307 C C . GLY O 1 85 ? 20.186 19.631 58.517 1.00 84.24 ? 85 GLY O C 1 +ATOM 27308 O O . GLY O 1 85 ? 20.668 19.083 59.520 1.00 104.49 ? 85 GLY O O 1 +ATOM 27309 N N . LEU O 1 86 ? 19.627 18.923 57.541 1.00 67.16 ? 86 LEU O N 1 +ATOM 27310 C CA . LEU O 1 86 ? 19.346 17.486 57.711 1.00 77.91 ? 86 LEU O CA 1 +ATOM 27311 C C . LEU O 1 86 ? 20.633 16.760 58.031 1.00 67.75 ? 86 LEU O C 1 +ATOM 27312 O O . LEU O 1 86 ? 20.629 15.714 58.688 1.00 73.25 ? 86 LEU O O 1 +ATOM 27313 C CB . LEU O 1 86 ? 18.659 16.910 56.445 1.00 101.03 ? 86 LEU O CB 1 +ATOM 27314 C CG . LEU O 1 86 ? 18.463 15.384 56.260 1.00 96.63 ? 86 LEU O CG 1 +ATOM 27315 C CD1 . LEU O 1 86 ? 17.644 14.759 57.375 1.00 85.30 ? 86 LEU O CD1 1 +ATOM 27316 C CD2 . LEU O 1 86 ? 17.816 15.097 54.893 1.00 77.68 ? 86 LEU O CD2 1 +ATOM 27317 N N . GLN O 1 87 ? 21.724 17.254 57.459 1.00 68.09 ? 87 GLN O N 1 +ATOM 27318 C CA . GLN O 1 87 ? 22.976 16.510 57.487 1.00 95.52 ? 87 GLN O CA 1 +ATOM 27319 C C . GLN O 1 87 ? 23.441 16.378 58.947 1.00 98.77 ? 87 GLN O C 1 +ATOM 27320 O O . GLN O 1 87 ? 23.897 15.293 59.383 1.00 76.92 ? 87 GLN O O 1 +ATOM 27321 C CB . GLN O 1 87 ? 24.025 17.193 56.588 1.00 99.94 ? 87 GLN O CB 1 +ATOM 27322 C CG . GLN O 1 87 ? 25.023 16.224 55.945 1.00 105.39 ? 87 GLN O CG 1 +ATOM 27323 C CD . GLN O 1 87 ? 24.379 14.942 55.387 1.00 103.92 ? 87 GLN O CD 1 +ATOM 27324 O OE1 . GLN O 1 87 ? 23.490 14.994 54.542 1.00 83.74 ? 87 GLN O OE1 1 +ATOM 27325 N NE2 . GLN O 1 87 ? 24.846 13.787 55.857 1.00 102.83 ? 87 GLN O NE2 1 +ATOM 27326 N N . ASN O 1 88 ? 23.254 17.458 59.707 1.00 84.36 ? 88 ASN O N 1 +ATOM 27327 C CA . ASN O 1 88 ? 23.666 17.489 61.118 1.00 80.73 ? 88 ASN O CA 1 +ATOM 27328 C C . ASN O 1 88 ? 22.801 16.583 61.966 1.00 65.61 ? 88 ASN O C 1 +ATOM 27329 O O . ASN O 1 88 ? 23.277 15.930 62.903 1.00 62.55 ? 88 ASN O O 1 +ATOM 27330 C CB . ASN O 1 88 ? 23.549 18.893 61.684 1.00 66.17 ? 88 ASN O CB 1 +ATOM 27331 C CG . ASN O 1 88 ? 24.389 19.900 60.940 1.00 61.15 ? 88 ASN O CG 1 +ATOM 27332 O OD1 . ASN O 1 88 ? 25.464 19.583 60.453 1.00 61.45 ? 88 ASN O OD1 1 +ATOM 27333 N ND2 . ASN O 1 88 ? 23.859 21.092 60.779 1.00 79.80 ? 88 ASN O ND2 1 +ATOM 27334 N N . LEU O 1 89 ? 21.544 16.503 61.571 1.00 53.05 ? 89 LEU O N 1 +ATOM 27335 C CA . LEU O 1 89 ? 20.598 15.659 62.255 1.00 60.54 ? 89 LEU O CA 1 +ATOM 27336 C C . LEU O 1 89 ? 21.058 14.195 62.126 1.00 70.85 ? 89 LEU O C 1 +ATOM 27337 O O . LEU O 1 89 ? 21.053 13.416 63.085 1.00 64.99 ? 89 LEU O O 1 +ATOM 27338 C CB . LEU O 1 89 ? 19.208 15.901 61.628 1.00 56.18 ? 89 LEU O CB 1 +ATOM 27339 C CG . LEU O 1 89 ? 17.988 15.742 62.496 1.00 64.17 ? 89 LEU O CG 1 +ATOM 27340 C CD1 . LEU O 1 89 ? 17.141 14.609 62.015 1.00 62.69 ? 89 LEU O CD1 1 +ATOM 27341 C CD2 . LEU O 1 89 ? 18.365 15.510 63.969 1.00 97.19 ? 89 LEU O CD2 1 +ATOM 27342 N N . LEU O 1 90 ? 21.476 13.828 60.915 1.00 93.89 ? 90 LEU O N 1 +ATOM 27343 C CA . LEU O 1 90 ? 21.847 12.430 60.608 1.00 75.95 ? 90 LEU O CA 1 +ATOM 27344 C C . LEU O 1 90 ? 23.163 12.093 61.247 1.00 74.82 ? 90 LEU O C 1 +ATOM 27345 O O . LEU O 1 90 ? 23.389 10.956 61.681 1.00 80.67 ? 90 LEU O O 1 +ATOM 27346 C CB . LEU O 1 90 ? 21.955 12.228 59.107 1.00 87.14 ? 90 LEU O CB 1 +ATOM 27347 C CG . LEU O 1 90 ? 20.664 12.478 58.314 1.00 95.52 ? 90 LEU O CG 1 +ATOM 27348 C CD1 . LEU O 1 90 ? 20.992 12.716 56.850 1.00 69.38 ? 90 LEU O CD1 1 +ATOM 27349 C CD2 . LEU O 1 90 ? 19.731 11.288 58.516 1.00 119.27 ? 90 LEU O CD2 1 +ATOM 27350 N N . ASN O 1 91 ? 24.000 13.117 61.395 1.00 86.73 ? 91 ASN O N 1 +ATOM 27351 C CA . ASN O 1 91 ? 25.267 12.971 62.098 1.00 99.31 ? 91 ASN O CA 1 +ATOM 27352 C C . ASN O 1 91 ? 25.072 12.677 63.608 1.00 85.58 ? 91 ASN O C 1 +ATOM 27353 O O . ASN O 1 91 ? 25.669 11.748 64.155 1.00 53.43 ? 91 ASN O O 1 +ATOM 27354 C CB . ASN O 1 91 ? 26.085 14.247 61.901 1.00 82.66 ? 91 ASN O CB 1 +ATOM 27355 C CG . ASN O 1 91 ? 27.326 14.054 61.105 1.00 94.82 ? 91 ASN O CG 1 +ATOM 27356 O OD1 . ASN O 1 91 ? 27.527 13.046 60.416 1.00 83.90 ? 91 ASN O OD1 1 +ATOM 27357 N ND2 . ASN O 1 91 ? 28.233 15.012 61.262 1.00 138.05 ? 91 ASN O ND2 1 +ATOM 27358 N N . GLU O 1 92 ? 24.243 13.474 64.271 1.00 81.75 ? 92 GLU O N 1 +ATOM 27359 C CA . GLU O 1 92 ? 23.980 13.244 65.682 1.00 92.52 ? 92 GLU O CA 1 +ATOM 27360 C C . GLU O 1 92 ? 23.450 11.834 65.877 1.00 73.16 ? 92 GLU O C 1 +ATOM 27361 O O . GLU O 1 92 ? 23.666 11.204 66.903 1.00 66.57 ? 92 GLU O O 1 +ATOM 27362 C CB . GLU O 1 92 ? 23.006 14.311 66.243 1.00 118.75 ? 92 GLU O CB 1 +ATOM 27363 C CG . GLU O 1 92 ? 23.686 15.520 66.891 1.00 111.98 ? 92 GLU O CG 1 +ATOM 27364 C CD . GLU O 1 92 ? 24.706 15.151 67.980 1.00 84.64 ? 92 GLU O CD 1 +ATOM 27365 O OE1 . GLU O 1 92 ? 24.373 14.455 68.966 1.00 52.66 ? 92 GLU O OE1 1 +ATOM 27366 O OE2 . GLU O 1 92 ? 25.886 15.552 67.827 1.00 90.86 ? 92 GLU O OE2 1 +ATOM 27367 N N . ARG O 1 93 ? 22.643 11.395 64.934 1.00 70.78 ? 93 ARG O N 1 +ATOM 27368 C CA . ARG O 1 93 ? 22.027 10.095 65.048 1.00 84.09 ? 93 ARG O CA 1 +ATOM 27369 C C . ARG O 1 93 ? 23.087 9.018 64.883 1.00 75.11 ? 93 ARG O C 1 +ATOM 27370 O O . ARG O 1 93 ? 23.006 7.953 65.492 1.00 64.06 ? 93 ARG O O 1 +ATOM 27371 C CB . ARG O 1 93 ? 20.846 9.985 64.052 1.00 108.28 ? 93 ARG O CB 1 +ATOM 27372 C CG . ARG O 1 93 ? 19.651 10.864 64.475 1.00 109.25 ? 93 ARG O CG 1 +ATOM 27373 C CD . ARG O 1 93 ? 18.616 11.078 63.385 1.00 108.02 ? 93 ARG O CD 1 +ATOM 27374 N NE . ARG O 1 93 ? 17.447 10.230 63.543 1.00 112.00 ? 93 ARG O NE 1 +ATOM 27375 C CZ . ARG O 1 93 ? 17.264 9.061 62.922 1.00 115.13 ? 93 ARG O CZ 1 +ATOM 27376 N NH1 . ARG O 1 93 ? 18.170 8.546 62.087 1.00 90.28 ? 93 ARG O NH1 1 +ATOM 27377 N NH2 . ARG O 1 93 ? 16.136 8.413 63.145 1.00 132.16 ? 93 ARG O NH2 1 +ATOM 27378 N N . LYS O 1 94 ? 24.099 9.297 64.070 1.00 86.88 ? 94 LYS O N 1 +ATOM 27379 C CA . LYS O 1 94 ? 25.215 8.355 63.921 1.00 101.31 ? 94 LYS O CA 1 +ATOM 27380 C C . LYS O 1 94 ? 25.959 8.253 65.238 1.00 102.77 ? 94 LYS O C 1 +ATOM 27381 O O . LYS O 1 94 ? 26.347 7.148 65.649 1.00 123.91 ? 94 LYS O O 1 +ATOM 27382 C CB . LYS O 1 94 ? 26.193 8.826 62.846 1.00 108.42 ? 94 LYS O CB 1 +ATOM 27383 C CG . LYS O 1 94 ? 25.895 8.363 61.423 1.00 111.77 ? 94 LYS O CG 1 +ATOM 27384 C CD . LYS O 1 94 ? 26.818 9.067 60.437 1.00 117.30 ? 94 LYS O CD 1 +ATOM 27385 C CE . LYS O 1 94 ? 26.923 8.348 59.102 1.00 113.09 ? 94 LYS O CE 1 +ATOM 27386 N NZ . LYS O 1 94 ? 27.542 9.249 58.090 1.00 127.38 ? 94 LYS O NZ 1 +ATOM 27387 N N . ILE O 1 95 ? 26.142 9.400 65.901 1.00 74.43 ? 95 ILE O N 1 +ATOM 27388 C CA . ILE O 1 95 ? 26.919 9.415 67.128 1.00 59.00 ? 95 ILE O CA 1 +ATOM 27389 C C . ILE O 1 95 ? 26.159 8.685 68.216 1.00 67.99 ? 95 ILE O C 1 +ATOM 27390 O O . ILE O 1 95 ? 26.767 8.010 69.081 1.00 43.24 ? 95 ILE O O 1 +ATOM 27391 C CB . ILE O 1 95 ? 27.233 10.820 67.614 1.00 67.97 ? 95 ILE O CB 1 +ATOM 27392 C CG1 . ILE O 1 95 ? 27.791 11.673 66.485 1.00 100.61 ? 95 ILE O CG1 1 +ATOM 27393 C CG2 . ILE O 1 95 ? 28.278 10.719 68.700 1.00 69.05 ? 95 ILE O CG2 1 +ATOM 27394 C CD1 . ILE O 1 95 ? 28.451 12.974 66.917 1.00 123.03 ? 95 ILE O CD1 1 +ATOM 27395 N N . ILE O 1 96 ? 24.823 8.893 68.219 1.00 89.85 ? 96 ILE O N 1 +ATOM 27396 C CA . ILE O 1 96 ? 23.910 8.215 69.160 1.00 71.82 ? 96 ILE O CA 1 +ATOM 27397 C C . ILE O 1 96 ? 24.036 6.733 69.003 1.00 61.52 ? 96 ILE O C 1 +ATOM 27398 O O . ILE O 1 96 ? 24.427 6.041 69.945 1.00 59.84 ? 96 ILE O O 1 +ATOM 27399 C CB . ILE O 1 96 ? 22.440 8.594 68.947 1.00 53.71 ? 96 ILE O CB 1 +ATOM 27400 C CG1 . ILE O 1 96 ? 22.207 10.055 69.366 1.00 75.55 ? 96 ILE O CG1 1 +ATOM 27401 C CG2 . ILE O 1 96 ? 21.574 7.724 69.824 1.00 50.96 ? 96 ILE O CG2 1 +ATOM 27402 C CD1 . ILE O 1 96 ? 20.765 10.496 69.261 1.00 86.18 ? 96 ILE O CD1 1 +ATOM 27403 N N . ARG O 1 97 ? 23.787 6.267 67.793 1.00 61.05 ? 97 ARG O N 1 +ATOM 27404 C CA . ARG O 1 97 ? 23.849 4.838 67.520 1.00 82.94 ? 97 ARG O CA 1 +ATOM 27405 C C . ARG O 1 97 ? 25.220 4.229 67.847 1.00 98.71 ? 97 ARG O C 1 +ATOM 27406 O O . ARG O 1 97 ? 25.323 3.060 68.236 1.00 116.14 ? 97 ARG O O 1 +ATOM 27407 C CB . ARG O 1 97 ? 23.494 4.548 66.059 1.00 96.28 ? 97 ARG O CB 1 +ATOM 27408 C CG . ARG O 1 97 ? 22.076 4.032 65.844 1.00 109.07 ? 97 ARG O CG 1 +ATOM 27409 C CD . ARG O 1 97 ? 21.809 3.702 64.376 1.00 95.93 ? 97 ARG O CD 1 +ATOM 27410 N NE . ARG O 1 97 ? 21.482 4.886 63.586 1.00 81.64 ? 97 ARG O NE 1 +ATOM 27411 C CZ . ARG O 1 97 ? 20.245 5.275 63.282 1.00 93.74 ? 97 ARG O CZ 1 +ATOM 27412 N NH1 . ARG O 1 97 ? 19.179 4.571 63.677 1.00 70.24 ? 97 ARG O NH1 1 +ATOM 27413 N NH2 . ARG O 1 97 ? 20.076 6.395 62.581 1.00 122.19 ? 97 ARG O NH2 1 +ATOM 27414 N N . ALA O 1 98 ? 26.276 5.015 67.686 1.00 105.36 ? 98 ALA O N 1 +ATOM 27415 C CA . ALA O 1 98 ? 27.618 4.537 67.989 1.00 104.86 ? 98 ALA O CA 1 +ATOM 27416 C C . ALA O 1 98 ? 27.839 4.495 69.499 1.00 100.17 ? 98 ALA O C 1 +ATOM 27417 O O . ALA O 1 98 ? 28.632 3.689 69.988 1.00 86.96 ? 98 ALA O O 1 +ATOM 27418 C CB . ALA O 1 98 ? 28.645 5.428 67.308 1.00 122.30 ? 98 ALA O CB 1 +ATOM 27419 N N . ALA O 1 99 ? 27.132 5.372 70.220 1.00 96.14 ? 99 ALA O N 1 +ATOM 27420 C CA . ALA O 1 99 ? 27.235 5.468 71.689 1.00 91.93 ? 99 ALA O CA 1 +ATOM 27421 C C . ALA O 1 99 ? 26.628 4.283 72.395 1.00 92.27 ? 99 ALA O C 1 +ATOM 27422 O O . ALA O 1 99 ? 27.274 3.619 73.209 1.00 141.97 ? 99 ALA O O 1 +ATOM 27423 C CB . ALA O 1 99 ? 26.537 6.711 72.180 1.00 103.25 ? 99 ALA O CB 1 +ATOM 27424 N N . GLN O 1 100 ? 25.404 3.946 72.006 1.00 103.16 ? 100 GLN O N 1 +ATOM 27425 C CA . GLN O 1 100 ? 24.601 2.975 72.764 1.00 105.70 ? 100 GLN O CA 1 +ATOM 27426 C C . GLN O 1 100 ? 24.451 1.577 72.139 1.00 95.47 ? 100 GLN O C 1 +ATOM 27427 O O . GLN O 1 100 ? 23.726 0.735 72.659 1.00 95.38 ? 100 GLN O O 1 +ATOM 27428 C CB . GLN O 1 100 ? 23.217 3.558 73.036 1.00 99.12 ? 100 GLN O CB 1 +ATOM 27429 C CG . GLN O 1 100 ? 22.564 4.233 71.853 1.00 86.57 ? 100 GLN O CG 1 +ATOM 27430 C CD . GLN O 1 100 ? 21.590 5.316 72.276 1.00 77.36 ? 100 GLN O CD 1 +ATOM 27431 O OE1 . GLN O 1 100 ? 21.960 6.334 72.908 1.00 63.01 ? 100 GLN O OE1 1 +ATOM 27432 N NE2 . GLN O 1 100 ? 20.337 5.135 71.874 1.00 70.63 ? 100 GLN O NE2 1 +ATOM 27433 N N . GLU O 1 101 ? 25.190 1.312 71.072 1.00 107.37 ? 101 GLU O N 1 +ATOM 27434 C CA . GLU O 1 101 ? 25.120 0.016 70.408 1.00 116.86 ? 101 GLU O CA 1 +ATOM 27435 C C . GLU O 1 101 ? 25.656 -1.128 71.270 1.00 122.33 ? 101 GLU O C 1 +ATOM 27436 O O . GLU O 1 101 ? 25.302 -2.292 71.050 1.00 134.54 ? 101 GLU O O 1 +ATOM 27437 C CB . GLU O 1 101 ? 25.852 0.061 69.055 1.00 131.09 ? 101 GLU O CB 1 +ATOM 27438 C CG . GLU O 1 101 ? 27.288 0.586 69.110 1.00 129.00 ? 101 GLU O CG 1 +ATOM 27439 C CD . GLU O 1 101 ? 27.972 0.555 67.756 1.00 132.22 ? 101 GLU O CD 1 +ATOM 27440 O OE1 . GLU O 1 101 ? 27.262 0.408 66.729 1.00 134.83 ? 101 GLU O OE1 1 +ATOM 27441 O OE2 . GLU O 1 101 ? 29.225 0.601 67.709 1.00 140.15 ? 101 GLU O OE2 1 +ATOM 27442 N N . ASN O 1 102 ? 26.543 -0.817 72.212 1.00 118.72 ? 102 ASN O N 1 +ATOM 27443 C CA . ASN O 1 102 ? 27.171 -1.854 73.022 1.00 122.94 ? 102 ASN O CA 1 +ATOM 27444 C C . ASN O 1 102 ? 26.421 -2.128 74.313 1.00 129.81 ? 102 ASN O C 1 +ATOM 27445 O O . ASN O 1 102 ? 26.799 -3.022 75.073 1.00 141.74 ? 102 ASN O O 1 +ATOM 27446 C CB . ASN O 1 102 ? 28.610 -1.480 73.347 1.00 119.78 ? 102 ASN O CB 1 +ATOM 27447 C CG . ASN O 1 102 ? 29.513 -1.581 72.148 1.00 142.41 ? 102 ASN O CG 1 +ATOM 27448 O OD1 . ASN O 1 102 ? 29.939 -2.683 71.756 1.00 190.82 ? 102 ASN O OD1 1 +ATOM 27449 N ND2 . ASN O 1 102 ? 29.761 -0.444 71.508 1.00 151.76 ? 102 ASN O ND2 1 +ATOM 27450 N N . GLY O 1 103 ? 25.355 -1.376 74.565 1.00 117.99 ? 103 GLY O N 1 +ATOM 27451 C CA . GLY O 1 103 ? 24.569 -1.575 75.780 1.00 110.11 ? 103 GLY O CA 1 +ATOM 27452 C C . GLY O 1 103 ? 25.371 -1.388 77.049 1.00 106.43 ? 103 GLY O C 1 +ATOM 27453 O O . GLY O 1 103 ? 25.122 -2.042 78.069 1.00 136.01 ? 103 GLY O O 1 +ATOM 27454 N N . THR O 1 104 ? 26.333 -0.475 77.006 1.00 106.90 ? 104 THR O N 1 +ATOM 27455 C CA . THR O 1 104 ? 26.987 -0.018 78.219 1.00 107.98 ? 104 THR O CA 1 +ATOM 27456 C C . THR O 1 104 ? 26.399 1.326 78.660 1.00 109.26 ? 104 THR O C 1 +ATOM 27457 O O . THR O 1 104 ? 26.384 1.622 79.850 1.00 115.48 ? 104 THR O O 1 +ATOM 27458 C CB . THR O 1 104 ? 28.518 0.098 78.053 1.00 99.74 ? 104 THR O CB 1 +ATOM 27459 O OG1 . THR O 1 104 ? 28.832 1.125 77.099 1.00 84.14 ? 104 THR O OG1 1 +ATOM 27460 C CG2 . THR O 1 104 ? 29.111 -1.237 77.618 1.00 87.47 ? 104 THR O CG2 1 +ATOM 27461 N N . VAL O 1 105 ? 25.851 2.102 77.725 1.00 100.37 ? 105 VAL O N 1 +ATOM 27462 C CA . VAL O 1 105 ? 25.431 3.473 78.042 1.00 123.33 ? 105 VAL O CA 1 +ATOM 27463 C C . VAL O 1 105 ? 24.355 3.472 79.123 1.00 137.11 ? 105 VAL O C 1 +ATOM 27464 O O . VAL O 1 105 ? 23.463 2.608 79.140 1.00 122.51 ? 105 VAL O O 1 +ATOM 27465 C CB . VAL O 1 105 ? 24.978 4.283 76.789 1.00 150.64 ? 105 VAL O CB 1 +ATOM 27466 C CG1 . VAL O 1 105 ? 23.855 5.265 77.117 1.00 138.98 ? 105 VAL O CG1 1 +ATOM 27467 C CG2 . VAL O 1 105 ? 26.164 5.041 76.171 1.00 157.34 ? 105 VAL O CG2 1 +ATOM 27468 N N . ALA O 1 106 ? 24.480 4.441 80.031 1.00 157.03 ? 106 ALA O N 1 +ATOM 27469 C CA . ALA O 1 106 ? 23.661 4.524 81.234 1.00 149.14 ? 106 ALA O CA 1 +ATOM 27470 C C . ALA O 1 106 ? 22.186 4.696 80.884 1.00 165.37 ? 106 ALA O C 1 +ATOM 27471 O O . ALA O 1 106 ? 21.831 5.509 80.028 1.00 173.87 ? 106 ALA O O 1 +ATOM 27472 C CB . ALA O 1 106 ? 24.136 5.676 82.104 1.00 125.12 ? 106 ALA O CB 1 +ATOM 27473 N N . ILE O 1 107 ? 21.333 3.922 81.553 1.00 163.26 ? 107 ILE O N 1 +ATOM 27474 C CA . ILE O 1 107 ? 19.903 3.860 81.230 1.00 159.48 ? 107 ILE O CA 1 +ATOM 27475 C C . ILE O 1 107 ? 19.203 5.239 81.328 1.00 146.56 ? 107 ILE O C 1 +ATOM 27476 O O . ILE O 1 107 ? 18.251 5.522 80.596 1.00 96.10 ? 107 ILE O O 1 +ATOM 27477 C CB . ILE O 1 107 ? 19.188 2.815 82.129 1.00 144.62 ? 107 ILE O CB 1 +ATOM 27478 C CG1 . ILE O 1 107 ? 17.776 2.512 81.609 1.00 141.96 ? 107 ILE O CG1 1 +ATOM 27479 C CG2 . ILE O 1 107 ? 19.138 3.297 83.576 1.00 141.38 ? 107 ILE O CG2 1 +ATOM 27480 C CD1 . ILE O 1 107 ? 17.720 2.008 80.179 1.00 139.74 ? 107 ILE O CD1 1 +ATOM 27481 N N . ASN O 1 108 ? 19.694 6.090 82.224 1.00 153.61 ? 108 ASN O N 1 +ATOM 27482 C CA . ASN O 1 108 ? 19.204 7.467 82.351 1.00 149.62 ? 108 ASN O CA 1 +ATOM 27483 C C . ASN O 1 108 ? 19.620 8.314 81.157 1.00 143.49 ? 108 ASN O C 1 +ATOM 27484 O O . ASN O 1 108 ? 18.894 9.207 80.724 1.00 158.13 ? 108 ASN O O 1 +ATOM 27485 C CB . ASN O 1 108 ? 19.757 8.119 83.625 1.00 165.60 ? 108 ASN O CB 1 +ATOM 27486 C CG . ASN O 1 108 ? 20.000 7.116 84.737 1.00 184.06 ? 108 ASN O CG 1 +ATOM 27487 O OD1 . ASN O 1 108 ? 19.096 6.800 85.510 1.00 236.79 ? 108 ASN O OD1 1 +ATOM 27488 N ND2 . ASN O 1 108 ? 21.225 6.604 84.821 1.00 177.76 ? 108 ASN O ND2 1 +ATOM 27489 N N . ASN O 1 109 ? 20.815 8.037 80.650 1.00 141.31 ? 109 ASN O N 1 +ATOM 27490 C CA . ASN O 1 109 ? 21.420 8.824 79.583 1.00 151.25 ? 109 ASN O CA 1 +ATOM 27491 C C . ASN O 1 109 ? 21.000 8.368 78.182 1.00 141.84 ? 109 ASN O C 1 +ATOM 27492 O O . ASN O 1 109 ? 21.150 9.114 77.207 1.00 112.84 ? 109 ASN O O 1 +ATOM 27493 C CB . ASN O 1 109 ? 22.944 8.762 79.702 1.00 150.60 ? 109 ASN O CB 1 +ATOM 27494 C CG . ASN O 1 109 ? 23.558 10.115 79.990 1.00 176.66 ? 109 ASN O CG 1 +ATOM 27495 O OD1 . ASN O 1 109 ? 24.278 10.669 79.161 1.00 183.74 ? 109 ASN O OD1 1 +ATOM 27496 N ND2 . ASN O 1 109 ? 23.234 10.680 81.150 1.00 202.66 ? 109 ASN O ND2 1 +ATOM 27497 N N . ARG O 1 110 ? 20.448 7.158 78.104 1.00 135.83 ? 110 ARG O N 1 +ATOM 27498 C CA . ARG O 1 110 ? 20.092 6.511 76.830 1.00 108.62 ? 110 ARG O CA 1 +ATOM 27499 C C . ARG O 1 110 ? 19.143 7.377 75.991 1.00 93.96 ? 110 ARG O C 1 +ATOM 27500 O O . ARG O 1 110 ? 18.163 7.914 76.513 1.00 104.53 ? 110 ARG O O 1 +ATOM 27501 C CB . ARG O 1 110 ? 19.421 5.156 77.120 1.00 105.21 ? 110 ARG O CB 1 +ATOM 27502 C CG . ARG O 1 110 ? 19.509 4.141 75.997 1.00 119.66 ? 110 ARG O CG 1 +ATOM 27503 C CD . ARG O 1 110 ? 19.629 2.719 76.522 1.00 122.74 ? 110 ARG O CD 1 +ATOM 27504 N NE . ARG O 1 110 ? 18.316 2.098 76.728 1.00 154.02 ? 110 ARG O NE 1 +ATOM 27505 C CZ . ARG O 1 110 ? 17.883 0.990 76.115 1.00 171.13 ? 110 ARG O CZ 1 +ATOM 27506 N NH1 . ARG O 1 110 ? 18.645 0.337 75.232 1.00 155.43 ? 110 ARG O NH1 1 +ATOM 27507 N NH2 . ARG O 1 110 ? 16.674 0.515 76.403 1.00 173.26 ? 110 ARG O NH2 1 +ATOM 27508 N N . ILE O 1 111 ? 19.426 7.511 74.698 1.00 78.74 ? 111 ILE O N 1 +ATOM 27509 C CA . ILE O 1 111 ? 18.505 8.202 73.792 1.00 76.95 ? 111 ILE O CA 1 +ATOM 27510 C C . ILE O 1 111 ? 17.826 7.218 72.849 1.00 84.80 ? 111 ILE O C 1 +ATOM 27511 O O . ILE O 1 111 ? 18.509 6.587 72.058 1.00 76.14 ? 111 ILE O O 1 +ATOM 27512 C CB . ILE O 1 111 ? 19.222 9.250 72.948 1.00 70.56 ? 111 ILE O CB 1 +ATOM 27513 C CG1 . ILE O 1 111 ? 19.782 10.338 73.856 1.00 86.99 ? 111 ILE O CG1 1 +ATOM 27514 C CG2 . ILE O 1 111 ? 18.258 9.856 71.936 1.00 68.18 ? 111 ILE O CG2 1 +ATOM 27515 C CD1 . ILE O 1 111 ? 20.760 11.280 73.175 1.00 113.60 ? 111 ILE O CD1 1 +ATOM 27516 N N . PRO O 1 112 ? 16.482 7.092 72.926 1.00 105.28 ? 112 PRO O N 1 +ATOM 27517 C CA . PRO O 1 112 ? 15.768 6.121 72.104 1.00 96.93 ? 112 PRO O CA 1 +ATOM 27518 C C . PRO O 1 112 ? 15.552 6.684 70.711 1.00 122.60 ? 112 PRO O C 1 +ATOM 27519 O O . PRO O 1 112 ? 15.105 7.833 70.556 1.00 85.81 ? 112 PRO O O 1 +ATOM 27520 C CB . PRO O 1 112 ? 14.446 5.948 72.831 1.00 81.11 ? 112 PRO O CB 1 +ATOM 27521 C CG . PRO O 1 112 ? 14.209 7.280 73.467 1.00 101.79 ? 112 PRO O CG 1 +ATOM 27522 C CD . PRO O 1 112 ? 15.555 7.906 73.734 1.00 116.72 ? 112 PRO O CD 1 +ATOM 27523 N N . LEU O 1 113 ? 15.945 5.900 69.708 1.00 159.44 ? 113 LEU O N 1 +ATOM 27524 C CA . LEU O 1 113 ? 15.957 6.362 68.329 1.00 138.94 ? 113 LEU O CA 1 +ATOM 27525 C C . LEU O 1 113 ? 14.838 5.752 67.532 1.00 112.45 ? 113 LEU O C 1 +ATOM 27526 O O . LEU O 1 113 ? 14.531 4.551 67.618 1.00 117.99 ? 113 LEU O O 1 +ATOM 27527 C CB . LEU O 1 113 ? 17.288 6.071 67.643 1.00 120.87 ? 113 LEU O CB 1 +ATOM 27528 C CG . LEU O 1 113 ? 18.347 7.145 67.841 1.00 124.00 ? 113 LEU O CG 1 +ATOM 27529 C CD1 . LEU O 1 113 ? 19.555 6.741 67.023 1.00 144.56 ? 113 LEU O CD1 1 +ATOM 27530 C CD2 . LEU O 1 113 ? 17.873 8.539 67.434 1.00 124.52 ? 113 LEU O CD2 1 +ATOM 27531 N N . GLN O 1 114 ? 14.263 6.604 66.705 1.00 90.16 ? 114 GLN O N 1 +ATOM 27532 C CA . GLN O 1 114 ? 13.056 6.287 66.012 1.00 100.69 ? 114 GLN O CA 1 +ATOM 27533 C C . GLN O 1 114 ? 13.268 6.814 64.623 1.00 97.01 ? 114 GLN O C 1 +ATOM 27534 O O . GLN O 1 114 ? 13.977 7.815 64.452 1.00 139.45 ? 114 GLN O O 1 +ATOM 27535 C CB . GLN O 1 114 ? 11.894 6.990 66.704 1.00 94.49 ? 114 GLN O CB 1 +ATOM 27536 C CG . GLN O 1 114 ? 10.581 6.260 66.585 1.00 96.69 ? 114 GLN O CG 1 +ATOM 27537 C CD . GLN O 1 114 ? 9.426 7.218 66.642 1.00 107.26 ? 114 GLN O CD 1 +ATOM 27538 O OE1 . GLN O 1 114 ? 8.404 6.999 65.984 1.00 131.96 ? 114 GLN O OE1 1 +ATOM 27539 N NE2 . GLN O 1 114 ? 9.591 8.314 67.391 1.00 108.89 ? 114 GLN O NE2 1 +ATOM 27540 N N . SER O 1 115 ? 12.696 6.133 63.637 1.00 77.41 ? 115 SER O N 1 +ATOM 27541 C CA . SER O 1 115 ? 12.855 6.542 62.261 1.00 102.17 ? 115 SER O CA 1 +ATOM 27542 C C . SER O 1 115 ? 12.446 8.013 62.074 1.00 102.95 ? 115 SER O C 1 +ATOM 27543 O O . SER O 1 115 ? 11.646 8.556 62.850 1.00 70.12 ? 115 SER O O 1 +ATOM 27544 C CB . SER O 1 115 ? 12.028 5.647 61.333 1.00 115.49 ? 115 SER O CB 1 +ATOM 27545 O OG . SER O 1 115 ? 10.666 5.606 61.735 1.00 124.96 ? 115 SER O OG 1 +ATOM 27546 N N . LEU O 1 116 ? 13.020 8.673 61.069 1.00 99.35 ? 116 LEU O N 1 +ATOM 27547 C CA . LEU O 1 116 ? 12.850 10.101 61.005 1.00 97.57 ? 116 LEU O CA 1 +ATOM 27548 C C . LEU O 1 116 ? 11.417 10.321 60.599 1.00 111.38 ? 116 LEU O C 1 +ATOM 27549 O O . LEU O 1 116 ? 10.981 9.766 59.587 1.00 157.82 ? 116 LEU O O 1 +ATOM 27550 C CB . LEU O 1 116 ? 13.804 10.748 60.002 1.00 101.87 ? 116 LEU O CB 1 +ATOM 27551 C CG . LEU O 1 116 ? 15.285 10.705 60.356 1.00 86.68 ? 116 LEU O CG 1 +ATOM 27552 C CD1 . LEU O 1 116 ? 15.981 9.501 59.713 1.00 103.24 ? 116 LEU O CD1 1 +ATOM 27553 C CD2 . LEU O 1 116 ? 15.925 12.009 59.899 1.00 79.60 ? 116 LEU O CD2 1 +ATOM 27554 N N . THR O 1 117 ? 10.695 11.127 61.372 1.00 111.82 ? 117 THR O N 1 +ATOM 27555 C CA . THR O 1 117 ? 9.313 11.467 61.046 1.00 112.58 ? 117 THR O CA 1 +ATOM 27556 C C . THR O 1 117 ? 9.279 12.033 59.642 1.00 85.74 ? 117 THR O C 1 +ATOM 27557 O O . THR O 1 117 ? 10.069 12.922 59.320 1.00 102.05 ? 117 THR O O 1 +ATOM 27558 C CB . THR O 1 117 ? 8.719 12.507 62.023 1.00 113.35 ? 117 THR O CB 1 +ATOM 27559 O OG1 . THR O 1 117 ? 8.882 12.044 63.368 1.00 161.61 ? 117 THR O OG1 1 +ATOM 27560 C CG2 . THR O 1 117 ? 7.239 12.706 61.755 1.00 109.11 ? 117 THR O CG2 1 +ATOM 27561 N N . ALA O 1 118 ? 8.369 11.515 58.825 1.00 60.70 ? 118 ALA O N 1 +ATOM 27562 C CA . ALA O 1 118 ? 8.351 11.839 57.420 1.00 63.35 ? 118 ALA O CA 1 +ATOM 27563 C C . ALA O 1 118 ? 7.121 12.663 57.054 1.00 95.39 ? 118 ALA O C 1 +ATOM 27564 O O . ALA O 1 118 ? 5.990 12.359 57.475 1.00 128.28 ? 118 ALA O O 1 +ATOM 27565 C CB . ALA O 1 118 ? 8.386 10.581 56.605 1.00 46.50 ? 118 ALA O CB 1 +ATOM 27566 N N . ALA O 1 119 ? 7.336 13.620 56.160 1.00 88.79 ? 119 ALA O N 1 +ATOM 27567 C CA . ALA O 1 119 ? 6.307 14.547 55.739 1.00 86.26 ? 119 ALA O CA 1 +ATOM 27568 C C . ALA O 1 119 ? 5.429 14.002 54.608 1.00 92.68 ? 119 ALA O C 1 +ATOM 27569 O O . ALA O 1 119 ? 5.891 13.167 53.817 1.00 64.94 ? 119 ALA O O 1 +ATOM 27570 C CB . ALA O 1 119 ? 6.960 15.841 55.297 1.00 116.41 ? 119 ALA O CB 1 +ATOM 27571 N N . ASN O 1 120 ? 4.192 14.520 54.493 1.00 103.78 ? 120 ASN O N 1 +ATOM 27572 C CA . ASN O 1 120 ? 3.327 14.171 53.359 1.00 99.04 ? 120 ASN O CA 1 +ATOM 27573 C C . ASN O 1 120 ? 3.295 15.201 52.265 1.00 79.36 ? 120 ASN O C 1 +ATOM 27574 O O . ASN O 1 120 ? 3.445 14.885 51.066 1.00 101.99 ? 120 ASN O O 1 +ATOM 27575 C CB . ASN O 1 120 ? 1.900 13.932 53.786 1.00 100.96 ? 120 ASN O CB 1 +ATOM 27576 C CG . ASN O 1 120 ? 1.009 13.509 52.619 1.00 128.88 ? 120 ASN O CG 1 +ATOM 27577 O OD1 . ASN O 1 120 ? 1.434 12.802 51.683 1.00 93.53 ? 120 ASN O OD1 1 +ATOM 27578 N ND2 . ASN O 1 120 ? -0.232 13.990 52.646 1.00 175.23 ? 120 ASN O ND2 1 +ATOM 27579 N N . ILE O 1 121 ? 3.138 16.444 52.658 1.00 72.14 ? 121 ILE O N 1 +ATOM 27580 C CA . ILE O 1 121 ? 3.330 17.507 51.703 1.00 120.51 ? 121 ILE O CA 1 +ATOM 27581 C C . ILE O 1 121 ? 4.649 18.216 52.032 1.00 117.18 ? 121 ILE O C 1 +ATOM 27582 O O . ILE O 1 121 ? 4.971 18.428 53.179 1.00 108.44 ? 121 ILE O O 1 +ATOM 27583 C CB . ILE O 1 121 ? 2.116 18.479 51.680 1.00 152.38 ? 121 ILE O CB 1 +ATOM 27584 C CG1 . ILE O 1 121 ? 2.079 19.378 52.928 1.00 152.19 ? 121 ILE O CG1 1 +ATOM 27585 C CG2 . ILE O 1 121 ? 0.821 17.693 51.526 1.00 147.12 ? 121 ILE O CG2 1 +ATOM 27586 C CD1 . ILE O 1 121 ? 2.366 20.839 52.633 1.00 157.68 ? 121 ILE O CD1 1 +ATOM 27587 N N . MET O 1 122 ? 5.377 18.641 51.008 1.00 108.39 ? 122 MET O N 1 +ATOM 27588 C CA . MET O 1 122 ? 6.420 19.610 51.227 1.00 91.38 ? 122 MET O CA 1 +ATOM 27589 C C . MET O 1 122 ? 6.175 20.892 50.419 1.00 77.37 ? 122 MET O C 1 +ATOM 27590 O O . MET O 1 122 ? 5.575 20.859 49.345 1.00 64.57 ? 122 MET O O 1 +ATOM 27591 C CB . MET O 1 122 ? 7.752 18.970 50.897 1.00 119.05 ? 122 MET O CB 1 +ATOM 27592 C CG . MET O 1 122 ? 7.904 18.444 49.474 1.00 108.74 ? 122 MET O CG 1 +ATOM 27593 S SD . MET O 1 122 ? 9.641 18.522 48.995 1.00 99.81 ? 122 MET O SD 1 +ATOM 27594 C CE . MET O 1 122 ? 9.534 19.103 47.334 1.00 88.25 ? 122 MET O CE 1 +ATOM 27595 N N . VAL O 1 123 ? 6.506 22.027 51.016 1.00 62.50 ? 123 VAL O N 1 +ATOM 27596 C CA . VAL O 1 123 ? 6.248 23.300 50.371 1.00 79.83 ? 123 VAL O CA 1 +ATOM 27597 C C . VAL O 1 123 ? 7.536 24.031 50.110 1.00 81.17 ? 123 VAL O C 1 +ATOM 27598 O O . VAL O 1 123 ? 8.372 24.192 51.010 1.00 71.21 ? 123 VAL O O 1 +ATOM 27599 C CB . VAL O 1 123 ? 5.367 24.226 51.220 1.00 118.80 ? 123 VAL O CB 1 +ATOM 27600 C CG1 . VAL O 1 123 ? 5.731 24.140 52.695 1.00 131.13 ? 123 VAL O CG1 1 +ATOM 27601 C CG2 . VAL O 1 123 ? 5.457 25.678 50.725 1.00 152.39 ? 123 VAL O CG2 1 +ATOM 27602 N N . GLU O 1 124 ? 7.732 24.442 48.859 1.00 84.67 ? 124 GLU O N 1 +ATOM 27603 C CA . GLU O 1 124 ? 8.917 25.225 48.492 1.00 91.33 ? 124 GLU O CA 1 +ATOM 27604 C C . GLU O 1 124 ? 8.504 26.417 47.692 1.00 70.71 ? 124 GLU O C 1 +ATOM 27605 O O . GLU O 1 124 ? 7.373 26.554 47.327 1.00 50.44 ? 124 GLU O O 1 +ATOM 27606 C CB . GLU O 1 124 ? 9.946 24.419 47.680 1.00 118.08 ? 124 GLU O CB 1 +ATOM 27607 C CG . GLU O 1 124 ? 9.381 23.318 46.809 1.00 126.98 ? 124 GLU O CG 1 +ATOM 27608 C CD . GLU O 1 124 ? 10.456 22.340 46.380 1.00 144.10 ? 124 GLU O CD 1 +ATOM 27609 O OE1 . GLU O 1 124 ? 11.363 22.032 47.184 1.00 166.57 ? 124 GLU O OE1 1 +ATOM 27610 O OE2 . GLU O 1 124 ? 10.374 21.839 45.255 1.00 163.63 ? 124 GLU O OE2 1 +ATOM 27611 N N . GLY O 1 125 ? 9.451 27.318 47.495 1.00 91.15 ? 125 GLY O N 1 +ATOM 27612 C CA . GLY O 1 125 ? 9.166 28.598 46.895 1.00 94.12 ? 125 GLY O CA 1 +ATOM 27613 C C . GLY O 1 125 ? 10.428 29.403 46.653 1.00 88.38 ? 125 GLY O C 1 +ATOM 27614 O O . GLY O 1 125 ? 11.530 28.859 46.626 1.00 93.01 ? 125 GLY O O 1 +ATOM 27615 N N . SER O 1 126 ? 10.266 30.699 46.458 1.00 75.10 ? 126 SER O N 1 +ATOM 27616 C CA . SER O 1 126 ? 11.376 31.517 46.011 1.00 71.29 ? 126 SER O CA 1 +ATOM 27617 C C . SER O 1 126 ? 11.028 32.957 46.245 1.00 85.47 ? 126 SER O C 1 +ATOM 27618 O O . SER O 1 126 ? 9.868 33.349 46.156 1.00 92.99 ? 126 SER O O 1 +ATOM 27619 C CB . SER O 1 126 ? 11.672 31.335 44.510 1.00 61.74 ? 126 SER O CB 1 +ATOM 27620 O OG . SER O 1 126 ? 11.383 30.018 44.051 1.00 59.63 ? 126 SER O OG 1 +ATOM 27621 N N . ILE O 1 127 ? 12.039 33.765 46.520 1.00 95.28 ? 127 ILE O N 1 +ATOM 27622 C CA . ILE O 1 127 ? 11.849 35.207 46.504 1.00 81.19 ? 127 ILE O CA 1 +ATOM 27623 C C . ILE O 1 127 ? 11.938 35.630 45.073 1.00 84.85 ? 127 ILE O C 1 +ATOM 27624 O O . ILE O 1 127 ? 13.015 35.671 44.483 1.00 135.33 ? 127 ILE O O 1 +ATOM 27625 C CB . ILE O 1 127 ? 12.888 35.961 47.351 1.00 86.74 ? 127 ILE O CB 1 +ATOM 27626 C CG1 . ILE O 1 127 ? 12.695 35.658 48.861 1.00 84.66 ? 127 ILE O CG1 1 +ATOM 27627 C CG2 . ILE O 1 127 ? 12.773 37.456 47.100 1.00 85.50 ? 127 ILE O CG2 1 +ATOM 27628 C CD1 . ILE O 1 127 ? 13.971 35.711 49.691 1.00 53.84 ? 127 ILE O CD1 1 +ATOM 27629 N N . ILE O 1 128 ? 10.784 35.865 44.485 1.00 88.37 ? 128 ILE O N 1 +ATOM 27630 C CA . ILE O 1 128 ? 10.680 36.266 43.098 1.00 103.39 ? 128 ILE O CA 1 +ATOM 27631 C C . ILE O 1 128 ? 10.685 37.783 43.076 1.00 94.69 ? 128 ILE O C 1 +ATOM 27632 O O . ILE O 1 128 ? 9.695 38.434 43.437 1.00 106.42 ? 128 ILE O O 1 +ATOM 27633 C CB . ILE O 1 128 ? 9.289 35.989 42.509 1.00 109.41 ? 128 ILE O CB 1 +ATOM 27634 C CG1 . ILE O 1 128 ? 8.676 34.597 42.695 1.00 91.78 ? 128 ILE O CG1 1 +ATOM 27635 C CG2 . ILE O 1 128 ? 9.354 36.215 41.036 1.00 132.39 ? 128 ILE O CG2 1 +ATOM 27636 C CD1 . ILE O 1 128 ? 7.152 34.668 42.691 1.00 93.57 ? 128 ILE O CD1 1 +ATOM 27637 N N . GLY O 1 129 ? 11.825 38.347 42.754 1.00 76.61 ? 129 GLY O N 1 +ATOM 27638 C CA . GLY O 1 129 ? 11.877 39.776 42.500 1.00 104.45 ? 129 GLY O CA 1 +ATOM 27639 C C . GLY O 1 129 ? 11.948 40.770 43.670 1.00 117.55 ? 129 GLY O C 1 +ATOM 27640 O O . GLY O 1 129 ? 11.308 40.620 44.721 1.00 113.02 ? 129 GLY O O 1 +ATOM 27641 N N . TYR O 1 130 ? 12.843 41.736 43.500 1.00 115.12 ? 130 TYR O N 1 +ATOM 27642 C CA . TYR O 1 130 ? 12.897 42.928 44.337 1.00 89.25 ? 130 TYR O CA 1 +ATOM 27643 C C . TYR O 1 130 ? 13.247 44.066 43.421 1.00 83.50 ? 130 TYR O C 1 +ATOM 27644 O O . TYR O 1 130 ? 14.335 44.094 42.837 1.00 80.66 ? 130 TYR O O 1 +ATOM 27645 C CB . TYR O 1 130 ? 13.972 42.801 45.417 1.00 110.86 ? 130 TYR O CB 1 +ATOM 27646 C CG . TYR O 1 130 ? 14.194 44.049 46.227 1.00 111.85 ? 130 TYR O CG 1 +ATOM 27647 C CD1 . TYR O 1 130 ? 14.788 45.194 45.658 1.00 97.88 ? 130 TYR O CD1 1 +ATOM 27648 C CD2 . TYR O 1 130 ? 13.899 44.061 47.582 1.00 109.48 ? 130 TYR O CD2 1 +ATOM 27649 C CE1 . TYR O 1 130 ? 15.036 46.325 46.414 1.00 101.65 ? 130 TYR O CE1 1 +ATOM 27650 C CE2 . TYR O 1 130 ? 14.147 45.186 48.349 1.00 127.50 ? 130 TYR O CE2 1 +ATOM 27651 C CZ . TYR O 1 130 ? 14.705 46.319 47.760 1.00 113.37 ? 130 TYR O CZ 1 +ATOM 27652 O OH . TYR O 1 130 ? 14.891 47.426 48.552 1.00 99.38 ? 130 TYR O OH 1 +ATOM 27653 N N . GLU O 1 131 ? 12.253 44.859 43.087 1.00 117.87 ? 131 GLU O N 1 +ATOM 27654 C CA . GLU O 1 131 ? 12.500 46.030 42.255 1.00 151.93 ? 131 GLU O CA 1 +ATOM 27655 C C . GLU O 1 131 ? 12.643 47.199 43.209 1.00 153.55 ? 131 GLU O C 1 +ATOM 27656 O O . GLU O 1 131 ? 12.016 47.207 44.268 1.00 100.54 ? 131 GLU O O 1 +ATOM 27657 C CB . GLU O 1 131 ? 11.355 46.228 41.256 1.00 162.80 ? 131 GLU O CB 1 +ATOM 27658 C CG . GLU O 1 131 ? 11.575 47.321 40.222 1.00 157.37 ? 131 GLU O CG 1 +ATOM 27659 C CD . GLU O 1 131 ? 12.319 46.858 38.979 1.00 191.41 ? 131 GLU O CD 1 +ATOM 27660 O OE1 . GLU O 1 131 ? 12.222 45.656 38.619 1.00 285.66 ? 131 GLU O OE1 1 +ATOM 27661 O OE2 . GLU O 1 131 ? 12.968 47.708 38.329 1.00 176.14 ? 131 GLU O OE2 1 +ATOM 27662 N N . SER O 1 132 ? 13.481 48.165 42.842 1.00 155.26 ? 132 SER O N 1 +ATOM 27663 C CA . SER O 1 132 ? 13.829 49.239 43.756 1.00 151.62 ? 132 SER O CA 1 +ATOM 27664 C C . SER O 1 132 ? 13.408 50.619 43.227 1.00 159.09 ? 132 SER O C 1 +ATOM 27665 O O . SER O 1 132 ? 13.555 50.902 42.032 1.00 166.99 ? 132 SER O O 1 +ATOM 27666 C CB . SER O 1 132 ? 15.329 49.201 44.045 1.00 138.93 ? 132 SER O CB 1 +ATOM 27667 O OG . SER O 1 132 ? 15.980 50.334 43.502 1.00 113.98 ? 132 SER O OG 1 +ATOM 27668 N N . ASN O 1 133 ? 12.920 51.474 44.131 1.00 140.34 ? 133 ASN O N 1 +ATOM 27669 C CA . ASN O 1 133 ? 12.310 52.757 43.756 1.00 144.20 ? 133 ASN O CA 1 +ATOM 27670 C C . ASN O 1 133 ? 11.282 52.586 42.648 1.00 150.22 ? 133 ASN O C 1 +ATOM 27671 O O . ASN O 1 133 ? 11.383 53.186 41.576 1.00 94.49 ? 133 ASN O O 1 +ATOM 27672 C CB . ASN O 1 133 ? 13.359 53.781 43.323 1.00 134.04 ? 133 ASN O CB 1 +ATOM 27673 C CG . ASN O 1 133 ? 14.345 54.105 44.424 1.00 127.61 ? 133 ASN O CG 1 +ATOM 27674 O OD1 . ASN O 1 133 ? 14.039 54.017 45.625 1.00 82.24 ? 133 ASN O OD1 1 +ATOM 27675 N ND2 . ASN O 1 133 ? 15.552 54.472 44.019 1.00 127.50 ? 133 ASN O ND2 1 +ATOM 27676 N N . VAL O 1 134 ? 10.320 51.714 42.917 1.00 175.74 ? 134 VAL O N 1 +ATOM 27677 C CA . VAL O 1 134 ? 9.260 51.411 41.968 1.00 151.75 ? 134 VAL O CA 1 +ATOM 27678 C C . VAL O 1 134 ? 8.430 52.673 41.850 1.00 144.04 ? 134 VAL O C 1 +ATOM 27679 O O . VAL O 1 134 ? 7.913 52.999 40.786 1.00 114.38 ? 134 VAL O O 1 +ATOM 27680 C CB . VAL O 1 134 ? 8.414 50.204 42.453 1.00 160.97 ? 134 VAL O CB 1 +ATOM 27681 C CG1 . VAL O 1 134 ? 7.344 49.842 41.442 1.00 139.05 ? 134 VAL O CG1 1 +ATOM 27682 C CG2 . VAL O 1 134 ? 9.312 48.989 42.705 1.00 221.85 ? 134 VAL O CG2 1 +ATOM 27683 N N . LYS O 1 135 ? 8.298 53.378 42.971 1.00 181.38 ? 135 LYS O N 1 +ATOM 27684 C CA . LYS O 1 135 ? 7.796 54.749 42.945 1.00 188.41 ? 135 LYS O CA 1 +ATOM 27685 C C . LYS O 1 135 ? 8.621 55.650 43.849 1.00 180.23 ? 135 LYS O C 1 +ATOM 27686 O O . LYS O 1 135 ? 9.295 55.188 44.787 1.00 218.40 ? 135 LYS O O 1 +ATOM 27687 C CB . LYS O 1 135 ? 6.331 54.809 43.391 1.00 203.29 ? 135 LYS O CB 1 +ATOM 27688 C CG . LYS O 1 135 ? 5.379 54.052 42.482 1.00 197.75 ? 135 LYS O CG 1 +ATOM 27689 C CD . LYS O 1 135 ? 3.972 54.067 43.049 1.00 180.13 ? 135 LYS O CD 1 +ATOM 27690 C CE . LYS O 1 135 ? 3.009 53.301 42.171 1.00 169.19 ? 135 LYS O CE 1 +ATOM 27691 N NZ . LYS O 1 135 ? 1.614 53.734 42.437 1.00 162.55 ? 135 LYS O NZ 1 +ATOM 27692 N N . SER O 1 136 ? 8.524 56.948 43.590 1.00 130.64 ? 136 SER O N 1 +ATOM 27693 C CA . SER O 1 136 ? 9.234 57.930 44.378 1.00 108.45 ? 136 SER O CA 1 +ATOM 27694 C C . SER O 1 136 ? 8.653 59.301 44.169 1.00 80.66 ? 136 SER O C 1 +ATOM 27695 O O . SER O 1 136 ? 8.096 59.595 43.114 1.00 81.41 ? 136 SER O O 1 +ATOM 27696 C CB . SER O 1 136 ? 10.745 57.897 44.056 1.00 133.43 ? 136 SER O CB 1 +ATOM 27697 O OG . SER O 1 136 ? 11.239 59.165 43.647 1.00 121.79 ? 136 SER O OG 1 +ATOM 27698 N N . GLY O 1 137 ? 8.896 60.183 45.125 1.00 90.64 ? 137 GLY O N 1 +ATOM 27699 C CA . GLY O 1 137 ? 8.509 61.592 44.975 1.00 139.20 ? 137 GLY O CA 1 +ATOM 27700 C C . GLY O 1 137 ? 9.149 62.521 45.995 1.00 165.03 ? 137 GLY O C 1 +ATOM 27701 O O . GLY O 1 137 ? 9.841 62.064 46.908 1.00 236.54 ? 137 GLY O O 1 +ATOM 27702 N N . GLY O 1 138 ? 8.906 63.822 45.853 1.00 133.65 ? 138 GLY O N 1 +ATOM 27703 C CA . GLY O 1 138 ? 9.421 64.795 46.803 1.00 130.69 ? 138 GLY O CA 1 +ATOM 27704 C C . GLY O 1 138 ? 8.755 66.141 46.696 1.00 160.35 ? 138 GLY O C 1 +ATOM 27705 O O . GLY O 1 138 ? 8.341 66.554 45.614 1.00 189.01 ? 138 GLY O O 1 +ATOM 27706 N N . VAL O 1 139 ? 8.581 66.796 47.841 1.00 204.17 ? 139 VAL O N 1 +ATOM 27707 C CA . VAL O 1 139 ? 7.986 68.133 47.891 1.00 204.30 ? 139 VAL O CA 1 +ATOM 27708 C C . VAL O 1 139 ? 8.748 69.002 48.878 1.00 213.15 ? 139 VAL O C 1 +ATOM 27709 O O . VAL O 1 139 ? 8.915 68.635 50.046 1.00 223.43 ? 139 VAL O O 1 +ATOM 27710 C CB . VAL O 1 139 ? 6.504 68.103 48.318 1.00 167.57 ? 139 VAL O CB 1 +ATOM 27711 C CG1 . VAL O 1 139 ? 5.982 69.519 48.479 1.00 149.11 ? 139 VAL O CG1 1 +ATOM 27712 C CG2 . VAL O 1 139 ? 5.666 67.333 47.305 1.00 160.92 ? 139 VAL O CG2 1 +ATOM 27713 N N . GLY O 1 140 ? 9.204 70.159 48.405 1.00 212.10 ? 140 GLY O N 1 +ATOM 27714 C CA . GLY O 1 140 ? 9.974 71.078 49.235 1.00 224.93 ? 140 GLY O CA 1 +ATOM 27715 C C . GLY O 1 140 ? 9.788 72.539 48.877 1.00 204.88 ? 140 GLY O C 1 +ATOM 27716 O O . GLY O 1 140 ? 9.618 72.888 47.709 1.00 192.73 ? 140 GLY O O 1 +ATOM 27717 N N . ALA O 1 141 ? 9.820 73.396 49.893 1.00 193.55 ? 141 ALA O N 1 +ATOM 27718 C CA . ALA O 1 141 ? 9.685 74.833 49.687 1.00 177.79 ? 141 ALA O CA 1 +ATOM 27719 C C . ALA O 1 141 ? 10.552 75.632 50.652 1.00 173.17 ? 141 ALA O C 1 +ATOM 27720 O O . ALA O 1 141 ? 10.708 75.273 51.820 1.00 166.82 ? 141 ALA O O 1 +ATOM 27721 C CB . ALA O 1 141 ? 8.229 75.251 49.806 1.00 162.99 ? 141 ALA O CB 1 +ATOM 27722 N N . ARG O 1 142 ? 11.166 76.680 50.129 1.00 175.67 ? 142 ARG O N 1 +ATOM 27723 C CA . ARG O 1 142 ? 11.899 77.600 50.958 1.00 176.95 ? 142 ARG O CA 1 +ATOM 27724 C C . ARG O 1 142 ? 11.419 79.006 50.648 1.00 222.82 ? 142 ARG O C 1 +ATOM 27725 O O . ARG O 1 142 ? 11.075 79.319 49.506 1.00 258.73 ? 142 ARG O O 1 +ATOM 27726 C CB . ARG O 1 142 ? 13.410 77.468 50.738 1.00 167.85 ? 142 ARG O CB 1 +ATOM 27727 C CG . ARG O 1 142 ? 14.224 78.368 51.657 1.00 166.12 ? 142 ARG O CG 1 +ATOM 27728 C CD . ARG O 1 142 ? 15.451 77.682 52.237 1.00 164.80 ? 142 ARG O CD 1 +ATOM 27729 N NE . ARG O 1 142 ? 16.651 77.832 51.431 1.00 145.87 ? 142 ARG O NE 1 +ATOM 27730 C CZ . ARG O 1 142 ? 17.713 77.035 51.507 1.00 140.81 ? 142 ARG O CZ 1 +ATOM 27731 N NH1 . ARG O 1 142 ? 17.688 75.934 52.250 1.00 133.56 ? 142 ARG O NH1 1 +ATOM 27732 N NH2 . ARG O 1 142 ? 18.784 77.302 50.771 1.00 174.26 ? 142 ARG O NH2 1 +ATOM 27733 N N . TYR O 1 143 ? 11.375 79.842 51.681 1.00 242.69 ? 143 TYR O N 1 +ATOM 27734 C CA . TYR O 1 143 ? 10.821 81.190 51.583 1.00 231.35 ? 143 TYR O CA 1 +ATOM 27735 C C . TYR O 1 143 ? 11.770 82.240 52.178 1.00 189.61 ? 143 TYR O C 1 +ATOM 27736 O O . TYR O 1 143 ? 11.648 82.631 53.342 1.00 141.43 ? 143 TYR O O 1 +ATOM 27737 C CB . TYR O 1 143 ? 9.456 81.246 52.282 1.00 240.08 ? 143 TYR O CB 1 +ATOM 27738 C CG . TYR O 1 143 ? 8.776 82.572 52.109 1.00 256.27 ? 143 TYR O CG 1 +ATOM 27739 C CD1 . TYR O 1 143 ? 8.303 82.966 50.868 1.00 253.22 ? 143 TYR O CD1 1 +ATOM 27740 C CD2 . TYR O 1 143 ? 8.692 83.472 53.162 1.00 251.43 ? 143 TYR O CD2 1 +ATOM 27741 C CE1 . TYR O 1 143 ? 7.734 84.212 50.688 1.00 242.42 ? 143 TYR O CE1 1 +ATOM 27742 C CE2 . TYR O 1 143 ? 8.115 84.718 52.999 1.00 238.68 ? 143 TYR O CE2 1 +ATOM 27743 C CZ . TYR O 1 143 ? 7.639 85.083 51.758 1.00 233.94 ? 143 TYR O CZ 1 +ATOM 27744 O OH . TYR O 1 143 ? 7.070 86.318 51.580 1.00 231.20 ? 143 TYR O OH 1 +ATOM 27745 N N . GLY O 1 145 ? 13.966 82.583 53.739 1.00 163.70 ? 145 GLY O N 1 +ATOM 27746 C CA . GLY O 1 145 ? 14.898 82.155 54.777 1.00 147.15 ? 145 GLY O CA 1 +ATOM 27747 C C . GLY O 1 145 ? 14.561 80.824 55.436 1.00 150.32 ? 145 GLY O C 1 +ATOM 27748 O O . GLY O 1 145 ? 15.459 80.156 55.944 1.00 171.50 ? 145 GLY O O 1 +ATOM 27749 N N . ILE O 1 146 ? 13.288 80.417 55.394 1.00 168.55 ? 146 ILE O N 1 +ATOM 27750 C CA . ILE O 1 146 ? 12.807 79.217 56.111 1.00 173.45 ? 146 ILE O CA 1 +ATOM 27751 C C . ILE O 1 146 ? 12.357 78.157 55.096 1.00 188.00 ? 146 ILE O C 1 +ATOM 27752 O O . ILE O 1 146 ? 11.707 78.487 54.105 1.00 167.28 ? 146 ILE O O 1 +ATOM 27753 C CB . ILE O 1 146 ? 11.626 79.546 57.068 1.00 143.85 ? 146 ILE O CB 1 +ATOM 27754 C CG1 . ILE O 1 146 ? 11.855 80.901 57.756 1.00 145.33 ? 146 ILE O CG1 1 +ATOM 27755 C CG2 . ILE O 1 146 ? 11.446 78.444 58.106 1.00 119.39 ? 146 ILE O CG2 1 +ATOM 27756 C CD1 . ILE O 1 146 ? 11.161 82.065 57.082 1.00 140.06 ? 146 ILE O CD1 1 +ATOM 27757 N N . GLY O 1 147 ? 12.707 76.892 55.328 1.00 202.39 ? 147 GLY O N 1 +ATOM 27758 C CA . GLY O 1 147 ? 12.406 75.845 54.352 1.00 192.65 ? 147 GLY O CA 1 +ATOM 27759 C C . GLY O 1 147 ? 12.197 74.452 54.913 1.00 202.98 ? 147 GLY O C 1 +ATOM 27760 O O . GLY O 1 147 ? 12.700 74.107 55.980 1.00 233.06 ? 147 GLY O O 1 +ATOM 27761 N N . ALA O 1 148 ? 11.456 73.642 54.172 1.00 198.47 ? 148 ALA O N 1 +ATOM 27762 C CA . ALA O 1 148 ? 11.293 72.237 54.511 1.00 172.25 ? 148 ALA O CA 1 +ATOM 27763 C C . ALA O 1 148 ? 11.141 71.409 53.242 1.00 172.69 ? 148 ALA O C 1 +ATOM 27764 O O . ALA O 1 148 ? 10.923 71.952 52.150 1.00 240.69 ? 148 ALA O O 1 +ATOM 27765 C CB . ALA O 1 148 ? 10.101 72.048 55.446 1.00 137.90 ? 148 ALA O CB 1 +ATOM 27766 N N . ASP O 1 149 ? 11.259 70.096 53.389 1.00 138.77 ? 149 ASP O N 1 +ATOM 27767 C CA . ASP O 1 149 ? 11.036 69.191 52.275 1.00 144.43 ? 149 ASP O CA 1 +ATOM 27768 C C . ASP O 1 149 ? 10.849 67.761 52.765 1.00 145.31 ? 149 ASP O C 1 +ATOM 27769 O O . ASP O 1 149 ? 11.411 67.369 53.793 1.00 178.62 ? 149 ASP O O 1 +ATOM 27770 C CB . ASP O 1 149 ? 12.193 69.284 51.271 1.00 133.03 ? 149 ASP O CB 1 +ATOM 27771 C CG . ASP O 1 149 ? 13.386 68.501 51.697 1.00 141.69 ? 149 ASP O CG 1 +ATOM 27772 O OD1 . ASP O 1 149 ? 14.090 68.955 52.621 1.00 159.46 ? 149 ASP O OD1 1 +ATOM 27773 O OD2 . ASP O 1 149 ? 13.611 67.413 51.128 1.00 159.92 ? 149 ASP O OD2 1 +ATOM 27774 N N . THR O 1 150 ? 10.027 66.996 52.056 1.00 146.75 ? 150 THR O N 1 +ATOM 27775 C CA . THR O 1 150 ? 10.024 65.552 52.241 1.00 170.93 ? 150 THR O CA 1 +ATOM 27776 C C . THR O 1 150 ? 10.348 64.863 50.924 1.00 191.14 ? 150 THR O C 1 +ATOM 27777 O O . THR O 1 150 ? 10.123 65.416 49.844 1.00 235.60 ? 150 THR O O 1 +ATOM 27778 C CB . THR O 1 150 ? 8.677 65.022 52.786 1.00 148.25 ? 150 THR O CB 1 +ATOM 27779 O OG1 . THR O 1 150 ? 7.627 65.363 51.881 1.00 145.95 ? 150 THR O OG1 1 +ATOM 27780 C CG2 . THR O 1 150 ? 8.384 65.593 54.158 1.00 128.33 ? 150 THR O CG2 1 +ATOM 27781 N N . GLN O 1 151 ? 10.888 63.656 51.028 1.00 160.66 ? 151 GLN O N 1 +ATOM 27782 C CA . GLN O 1 151 ? 11.111 62.799 49.886 1.00 116.12 ? 151 GLN O CA 1 +ATOM 27783 C C . GLN O 1 151 ? 10.711 61.392 50.254 1.00 108.24 ? 151 GLN O C 1 +ATOM 27784 O O . GLN O 1 151 ? 10.878 60.978 51.383 1.00 119.45 ? 151 GLN O O 1 +ATOM 27785 C CB . GLN O 1 151 ? 12.575 62.849 49.517 1.00 113.16 ? 151 GLN O CB 1 +ATOM 27786 C CG . GLN O 1 151 ? 12.970 64.163 48.889 1.00 135.44 ? 151 GLN O CG 1 +ATOM 27787 C CD . GLN O 1 151 ? 14.450 64.424 49.006 1.00 164.54 ? 151 GLN O CD 1 +ATOM 27788 O OE1 . GLN O 1 151 ? 15.253 63.512 48.824 1.00 220.51 ? 151 GLN O OE1 1 +ATOM 27789 N NE2 . GLN O 1 151 ? 14.825 65.666 49.299 1.00 184.54 ? 151 GLN O NE2 1 +ATOM 27790 N N . TYR O 1 152 ? 10.117 60.668 49.321 1.00 124.51 ? 152 TYR O N 1 +ATOM 27791 C CA . TYR O 1 152 ? 9.755 59.282 49.597 1.00 144.10 ? 152 TYR O CA 1 +ATOM 27792 C C . TYR O 1 152 ? 10.108 58.360 48.442 1.00 164.20 ? 152 TYR O C 1 +ATOM 27793 O O . TYR O 1 152 ? 10.079 58.771 47.279 1.00 214.08 ? 152 TYR O O 1 +ATOM 27794 C CB . TYR O 1 152 ? 8.276 59.163 49.944 1.00 114.40 ? 152 TYR O CB 1 +ATOM 27795 C CG . TYR O 1 152 ? 7.383 58.580 48.853 1.00 118.27 ? 152 TYR O CG 1 +ATOM 27796 C CD1 . TYR O 1 152 ? 7.167 59.248 47.632 1.00 93.84 ? 152 TYR O CD1 1 +ATOM 27797 C CD2 . TYR O 1 152 ? 6.684 57.405 49.077 1.00 117.54 ? 152 TYR O CD2 1 +ATOM 27798 C CE1 . TYR O 1 152 ? 6.348 58.714 46.644 1.00 69.03 ? 152 TYR O CE1 1 +ATOM 27799 C CE2 . TYR O 1 152 ? 5.779 56.918 48.137 1.00 109.73 ? 152 TYR O CE2 1 +ATOM 27800 C CZ . TYR O 1 152 ? 5.625 57.571 46.918 1.00 84.87 ? 152 TYR O CZ 1 +ATOM 27801 O OH . TYR O 1 152 ? 4.727 57.072 46.014 1.00 81.41 ? 152 TYR O OH 1 +ATOM 27802 N N . GLN O 1 153 ? 10.503 57.133 48.773 1.00 137.31 ? 153 GLN O N 1 +ATOM 27803 C CA . GLN O 1 153 ? 10.702 56.111 47.765 1.00 118.05 ? 153 GLN O CA 1 +ATOM 27804 C C . GLN O 1 153 ? 10.047 54.822 48.236 1.00 130.82 ? 153 GLN O C 1 +ATOM 27805 O O . GLN O 1 153 ? 9.910 54.579 49.445 1.00 153.41 ? 153 GLN O O 1 +ATOM 27806 C CB . GLN O 1 153 ? 12.207 55.901 47.501 1.00 118.91 ? 153 GLN O CB 1 +ATOM 27807 C CG . GLN O 1 153 ? 12.894 57.102 46.864 1.00 115.37 ? 153 GLN O CG 1 +ATOM 27808 C CD . GLN O 1 153 ? 13.302 58.221 47.849 1.00 116.50 ? 153 GLN O CD 1 +ATOM 27809 O OE1 . GLN O 1 153 ? 13.153 58.091 49.069 1.00 106.42 ? 153 GLN O OE1 1 +ATOM 27810 N NE2 . GLN O 1 153 ? 13.888 59.293 47.316 1.00 102.81 ? 153 GLN O NE2 1 +ATOM 27811 N N . LEU O 1 154 ? 9.672 53.973 47.288 1.00 135.23 ? 154 LEU O N 1 +ATOM 27812 C CA . LEU O 1 154 ? 9.199 52.640 47.648 1.00 157.78 ? 154 LEU O CA 1 +ATOM 27813 C C . LEU O 1 154 ? 9.622 51.556 46.649 1.00 132.29 ? 154 LEU O C 1 +ATOM 27814 O O . LEU O 1 154 ? 9.615 51.782 45.434 1.00 109.63 ? 154 LEU O O 1 +ATOM 27815 C CB . LEU O 1 154 ? 7.675 52.644 47.850 1.00 177.35 ? 154 LEU O CB 1 +ATOM 27816 C CG . LEU O 1 154 ? 6.825 52.787 46.579 1.00 222.18 ? 154 LEU O CG 1 +ATOM 27817 C CD1 . LEU O 1 154 ? 6.393 51.430 46.043 1.00 211.55 ? 154 LEU O CD1 1 +ATOM 27818 C CD2 . LEU O 1 154 ? 5.623 53.672 46.862 1.00 260.62 ? 154 LEU O CD2 1 +ATOM 27819 N N . ASP O 1 155 ? 9.827 50.357 47.202 1.00 114.11 ? 155 ASP O N 1 +ATOM 27820 C CA . ASP O 1 155 ? 10.399 49.210 46.515 1.00 90.77 ? 155 ASP O CA 1 +ATOM 27821 C C . ASP O 1 155 ? 9.429 48.040 46.602 1.00 102.64 ? 155 ASP O C 1 +ATOM 27822 O O . ASP O 1 155 ? 8.488 48.048 47.416 1.00 91.22 ? 155 ASP O O 1 +ATOM 27823 C CB . ASP O 1 155 ? 11.692 48.805 47.196 1.00 108.20 ? 155 ASP O CB 1 +ATOM 27824 C CG . ASP O 1 155 ? 12.593 49.995 47.476 1.00 162.92 ? 155 ASP O CG 1 +ATOM 27825 O OD1 . ASP O 1 155 ? 12.355 50.714 48.483 1.00 222.92 ? 155 ASP O OD1 1 +ATOM 27826 O OD2 . ASP O 1 155 ? 13.549 50.214 46.703 1.00 185.31 ? 155 ASP O OD2 1 +ATOM 27827 N N . GLN O 1 156 ? 9.603 47.051 45.726 1.00 137.01 ? 156 GLN O N 1 +ATOM 27828 C CA . GLN O 1 156 ? 8.678 45.893 45.685 1.00 150.35 ? 156 GLN O CA 1 +ATOM 27829 C C . GLN O 1 156 ? 9.399 44.599 46.001 1.00 138.50 ? 156 GLN O C 1 +ATOM 27830 O O . GLN O 1 156 ? 10.614 44.516 45.866 1.00 157.45 ? 156 GLN O O 1 +ATOM 27831 C CB . GLN O 1 156 ? 8.002 45.770 44.315 1.00 147.33 ? 156 GLN O CB 1 +ATOM 27832 C CG . GLN O 1 156 ? 6.849 44.781 44.275 1.00 144.40 ? 156 GLN O CG 1 +ATOM 27833 C CD . GLN O 1 156 ? 5.897 45.035 43.113 1.00 146.39 ? 156 GLN O CD 1 +ATOM 27834 O OE1 . GLN O 1 156 ? 6.169 45.855 42.227 1.00 125.60 ? 156 GLN O OE1 1 +ATOM 27835 N NE2 . GLN O 1 156 ? 4.764 44.338 43.121 1.00 138.08 ? 156 GLN O NE2 1 +ATOM 27836 N N . ILE O 1 157 ? 8.657 43.626 46.507 1.00 107.76 ? 157 ILE O N 1 +ATOM 27837 C CA . ILE O 1 157 ? 9.223 42.326 46.799 1.00 113.38 ? 157 ILE O CA 1 +ATOM 27838 C C . ILE O 1 157 ? 8.105 41.306 46.598 1.00 121.77 ? 157 ILE O C 1 +ATOM 27839 O O . ILE O 1 157 ? 6.958 41.530 47.007 1.00 146.19 ? 157 ILE O O 1 +ATOM 27840 C CB . ILE O 1 157 ? 9.820 42.279 48.232 1.00 126.96 ? 157 ILE O CB 1 +ATOM 27841 C CG1 . ILE O 1 157 ? 10.892 41.194 48.353 1.00 115.78 ? 157 ILE O CG1 1 +ATOM 27842 C CG2 . ILE O 1 157 ? 8.728 42.051 49.278 1.00 145.25 ? 157 ILE O CG2 1 +ATOM 27843 C CD1 . ILE O 1 157 ? 11.659 41.204 49.669 1.00 96.95 ? 157 ILE O CD1 1 +ATOM 27844 N N . ALA O 1 158 ? 8.419 40.178 45.975 1.00 103.25 ? 158 ALA O N 1 +ATOM 27845 C CA . ALA O 1 158 ? 7.399 39.166 45.766 1.00 77.68 ? 158 ALA O CA 1 +ATOM 27846 C C . ALA O 1 158 ? 7.902 37.803 46.201 1.00 73.17 ? 158 ALA O C 1 +ATOM 27847 O O . ALA O 1 158 ? 9.107 37.528 46.135 1.00 104.89 ? 158 ALA O O 1 +ATOM 27848 C CB . ALA O 1 158 ? 6.953 39.178 44.317 1.00 56.93 ? 158 ALA O CB 1 +ATOM 27849 N N . VAL O 1 159 ? 6.977 36.954 46.624 1.00 53.67 ? 159 VAL O N 1 +ATOM 27850 C CA . VAL O 1 159 ? 7.324 35.634 47.085 1.00 74.89 ? 159 VAL O CA 1 +ATOM 27851 C C . VAL O 1 159 ? 6.391 34.537 46.562 1.00 91.25 ? 159 VAL O C 1 +ATOM 27852 O O . VAL O 1 159 ? 5.170 34.703 46.525 1.00 134.62 ? 159 VAL O O 1 +ATOM 27853 C CB . VAL O 1 159 ? 7.294 35.602 48.602 1.00 96.79 ? 159 VAL O CB 1 +ATOM 27854 C CG1 . VAL O 1 159 ? 7.166 34.172 49.113 1.00 122.42 ? 159 VAL O CG1 1 +ATOM 27855 C CG2 . VAL O 1 159 ? 8.543 36.248 49.157 1.00 109.34 ? 159 VAL O CG2 1 +ATOM 27856 N N . ASN O 1 160 ? 6.989 33.465 46.027 1.00 95.62 ? 160 ASN O N 1 +ATOM 27857 C CA . ASN O 1 160 ? 6.245 32.281 45.567 1.00 83.57 ? 160 ASN O CA 1 +ATOM 27858 C C . ASN O 1 160 ? 6.360 31.256 46.653 1.00 87.66 ? 160 ASN O C 1 +ATOM 27859 O O . ASN O 1 160 ? 7.452 31.022 47.175 1.00 99.85 ? 160 ASN O O 1 +ATOM 27860 C CB . ASN O 1 160 ? 6.856 31.732 44.261 1.00 82.49 ? 160 ASN O CB 1 +ATOM 27861 C CG . ASN O 1 160 ? 6.254 30.407 43.796 1.00 91.97 ? 160 ASN O CG 1 +ATOM 27862 O OD1 . ASN O 1 160 ? 6.010 29.491 44.569 1.00 78.25 ? 160 ASN O OD1 1 +ATOM 27863 N ND2 . ASN O 1 160 ? 5.984 30.325 42.498 1.00 112.56 ? 160 ASN O ND2 1 +ATOM 27864 N N . LEU O 1 161 ? 5.219 30.733 47.070 1.00 84.26 ? 161 LEU O N 1 +ATOM 27865 C CA . LEU O 1 161 ? 5.205 29.508 47.839 1.00 73.72 ? 161 LEU O CA 1 +ATOM 27866 C C . LEU O 1 161 ? 4.342 28.497 47.122 1.00 85.31 ? 161 LEU O C 1 +ATOM 27867 O O . LEU O 1 161 ? 3.356 28.833 46.489 1.00 102.15 ? 161 LEU O O 1 +ATOM 27868 C CB . LEU O 1 161 ? 4.663 29.764 49.234 1.00 72.25 ? 161 LEU O CB 1 +ATOM 27869 C CG . LEU O 1 161 ? 5.493 30.680 50.117 1.00 73.35 ? 161 LEU O CG 1 +ATOM 27870 C CD1 . LEU O 1 161 ? 4.739 30.992 51.399 1.00 89.30 ? 161 LEU O CD1 1 +ATOM 27871 C CD2 . LEU O 1 161 ? 6.821 30.018 50.423 1.00 91.02 ? 161 LEU O CD2 1 +ATOM 27872 N N . ARG O 1 162 ? 4.682 27.231 47.246 1.00 96.44 ? 162 ARG O N 1 +ATOM 27873 C CA . ARG O 1 162 ? 3.888 26.198 46.584 1.00 95.69 ? 162 ARG O CA 1 +ATOM 27874 C C . ARG O 1 162 ? 3.951 24.811 47.278 1.00 82.51 ? 162 ARG O C 1 +ATOM 27875 O O . ARG O 1 162 ? 5.023 24.322 47.633 1.00 72.37 ? 162 ARG O O 1 +ATOM 27876 C CB . ARG O 1 162 ? 4.254 26.115 45.094 1.00 85.97 ? 162 ARG O CB 1 +ATOM 27877 C CG . ARG O 1 162 ? 5.676 25.696 44.784 1.00 113.29 ? 162 ARG O CG 1 +ATOM 27878 C CD . ARG O 1 162 ? 5.773 25.259 43.337 1.00 107.27 ? 162 ARG O CD 1 +ATOM 27879 N NE . ARG O 1 162 ? 7.082 24.653 43.017 1.00 146.42 ? 162 ARG O NE 1 +ATOM 27880 C CZ . ARG O 1 162 ? 8.205 25.318 42.737 1.00 107.55 ? 162 ARG O CZ 1 +ATOM 27881 N NH1 . ARG O 1 162 ? 8.208 26.642 42.774 1.00 121.66 ? 162 ARG O NH1 1 +ATOM 27882 N NH2 . ARG O 1 162 ? 9.323 24.648 42.444 1.00 72.29 ? 162 ARG O NH2 1 +ATOM 27883 N N . VAL O 1 163 ? 2.775 24.220 47.467 1.00 72.63 ? 163 VAL O N 1 +ATOM 27884 C CA . VAL O 1 163 ? 2.630 22.907 48.097 1.00 73.99 ? 163 VAL O CA 1 +ATOM 27885 C C . VAL O 1 163 ? 2.767 21.844 47.063 1.00 72.02 ? 163 VAL O C 1 +ATOM 27886 O O . VAL O 1 163 ? 2.001 21.806 46.079 1.00 121.63 ? 163 VAL O O 1 +ATOM 27887 C CB . VAL O 1 163 ? 1.225 22.711 48.695 1.00 98.92 ? 163 VAL O CB 1 +ATOM 27888 C CG1 . VAL O 1 163 ? 1.094 21.304 49.283 1.00 72.56 ? 163 VAL O CG1 1 +ATOM 27889 C CG2 . VAL O 1 163 ? 0.923 23.814 49.722 1.00 130.37 ? 163 VAL O CG2 1 +ATOM 27890 N N . VAL O 1 164 ? 3.713 20.960 47.290 1.00 66.75 ? 164 VAL O N 1 +ATOM 27891 C CA . VAL O 1 164 ? 3.978 19.841 46.387 1.00 89.45 ? 164 VAL O CA 1 +ATOM 27892 C C . VAL O 1 164 ? 3.635 18.540 47.080 1.00 84.79 ? 164 VAL O C 1 +ATOM 27893 O O . VAL O 1 164 ? 3.958 18.366 48.263 1.00 112.63 ? 164 VAL O O 1 +ATOM 27894 C CB . VAL O 1 164 ? 5.457 19.760 46.007 1.00 118.55 ? 164 VAL O CB 1 +ATOM 27895 C CG1 . VAL O 1 164 ? 5.714 18.558 45.122 1.00 127.89 ? 164 VAL O CG1 1 +ATOM 27896 C CG2 . VAL O 1 164 ? 5.867 21.023 45.296 1.00 137.61 ? 164 VAL O CG2 1 +ATOM 27897 N N . ASN O 1 165 ? 2.948 17.657 46.355 1.00 63.73 ? 165 ASN O N 1 +ATOM 27898 C CA . ASN O 1 165 ? 2.544 16.390 46.926 1.00 57.01 ? 165 ASN O CA 1 +ATOM 27899 C C . ASN O 1 165 ? 3.647 15.365 46.778 1.00 75.70 ? 165 ASN O C 1 +ATOM 27900 O O . ASN O 1 165 ? 4.057 15.053 45.652 1.00 110.82 ? 165 ASN O O 1 +ATOM 27901 C CB . ASN O 1 165 ? 1.308 15.864 46.250 1.00 49.20 ? 165 ASN O CB 1 +ATOM 27902 C CG . ASN O 1 165 ? 0.785 14.638 46.944 1.00 55.57 ? 165 ASN O CG 1 +ATOM 27903 O OD1 . ASN O 1 165 ? 1.190 14.305 48.069 1.00 40.06 ? 165 ASN O OD1 1 +ATOM 27904 N ND2 . ASN O 1 165 ? -0.137 13.953 46.294 1.00 73.45 ? 165 ASN O ND2 1 +ATOM 27905 N N . VAL O 1 166 ? 4.134 14.849 47.909 1.00 77.64 ? 166 VAL O N 1 +ATOM 27906 C CA . VAL O 1 166 ? 5.272 13.925 47.932 1.00 70.06 ? 166 VAL O CA 1 +ATOM 27907 C C . VAL O 1 166 ? 4.946 12.668 47.198 1.00 75.40 ? 166 VAL O C 1 +ATOM 27908 O O . VAL O 1 166 ? 5.759 12.165 46.443 1.00 80.27 ? 166 VAL O O 1 +ATOM 27909 C CB . VAL O 1 166 ? 5.652 13.555 49.371 1.00 79.21 ? 166 VAL O CB 1 +ATOM 27910 C CG1 . VAL O 1 166 ? 6.355 12.212 49.443 1.00 65.27 ? 166 VAL O CG1 1 +ATOM 27911 C CG2 . VAL O 1 166 ? 6.511 14.684 49.984 1.00 128.41 ? 166 VAL O CG2 1 +ATOM 27912 N N . SER O 1 167 ? 3.702 12.236 47.341 1.00 91.82 ? 167 SER O N 1 +ATOM 27913 C CA . SER O 1 167 ? 3.270 10.969 46.781 1.00 100.28 ? 167 SER O CA 1 +ATOM 27914 C C . SER O 1 167 ? 3.167 10.971 45.255 1.00 102.67 ? 167 SER O C 1 +ATOM 27915 O O . SER O 1 167 ? 3.060 9.903 44.651 1.00 101.95 ? 167 SER O O 1 +ATOM 27916 C CB . SER O 1 167 ? 1.937 10.578 47.401 1.00 101.97 ? 167 SER O CB 1 +ATOM 27917 O OG . SER O 1 167 ? 1.966 10.791 48.800 1.00 150.25 ? 167 SER O OG 1 +ATOM 27918 N N . THR O 1 168 ? 3.215 12.151 44.628 1.00 97.56 ? 168 THR O N 1 +ATOM 27919 C CA . THR O 1 168 ? 3.057 12.247 43.175 1.00 96.75 ? 168 THR O CA 1 +ATOM 27920 C C . THR O 1 168 ? 4.055 13.203 42.500 1.00 77.93 ? 168 THR O C 1 +ATOM 27921 O O . THR O 1 168 ? 4.385 13.058 41.322 1.00 71.07 ? 168 THR O O 1 +ATOM 27922 C CB . THR O 1 168 ? 1.609 12.653 42.799 1.00 103.89 ? 168 THR O CB 1 +ATOM 27923 O OG1 . THR O 1 168 ? 1.223 13.830 43.531 1.00 108.84 ? 168 THR O OG1 1 +ATOM 27924 C CG2 . THR O 1 168 ? 0.629 11.512 43.103 1.00 101.36 ? 168 THR O CG2 1 +ATOM 27925 N N . GLY O 1 169 ? 4.375 14.281 43.175 1.00 59.47 ? 169 GLY O N 1 +ATOM 27926 C CA . GLY O 1 169 ? 5.031 15.360 42.487 1.00 65.21 ? 169 GLY O CA 1 +ATOM 27927 C C . GLY O 1 169 ? 4.098 16.379 41.847 1.00 92.83 ? 169 GLY O C 1 +ATOM 27928 O O . GLY O 1 169 ? 4.533 17.496 41.517 1.00 163.92 ? 169 GLY O O 1 +ATOM 27929 N N . GLU O 1 170 ? 2.797 16.101 41.834 1.00 101.85 ? 170 GLU O N 1 +ATOM 27930 C CA . GLU O 1 170 ? 1.801 17.140 41.569 1.00 118.03 ? 170 GLU O CA 1 +ATOM 27931 C C . GLU O 1 170 ? 2.007 18.311 42.527 1.00 112.79 ? 170 GLU O C 1 +ATOM 27932 O O . GLU O 1 170 ? 2.041 18.145 43.727 1.00 66.98 ? 170 GLU O O 1 +ATOM 27933 C CB . GLU O 1 170 ? 0.353 16.616 41.717 1.00 143.40 ? 170 GLU O CB 1 +ATOM 27934 C CG . GLU O 1 170 ? -0.116 15.734 40.559 1.00 159.39 ? 170 GLU O CG 1 +ATOM 27935 C CD . GLU O 1 170 ? -1.018 14.580 40.975 1.00 160.26 ? 170 GLU O CD 1 +ATOM 27936 O OE1 . GLU O 1 170 ? -1.127 14.311 42.190 1.00 165.45 ? 170 GLU O OE1 1 +ATOM 27937 O OE2 . GLU O 1 170 ? -1.553 13.885 40.081 1.00 153.09 ? 170 GLU O OE2 1 +ATOM 27938 N N . ILE O 1 171 ? 2.121 19.514 41.984 1.00 126.53 ? 171 ILE O N 1 +ATOM 27939 C CA . ILE O 1 171 ? 1.960 20.698 42.793 1.00 134.37 ? 171 ILE O CA 1 +ATOM 27940 C C . ILE O 1 171 ? 0.481 20.857 43.173 1.00 145.94 ? 171 ILE O C 1 +ATOM 27941 O O . ILE O 1 171 ? -0.386 20.844 42.312 1.00 134.64 ? 171 ILE O O 1 +ATOM 27942 C CB . ILE O 1 171 ? 2.439 21.931 42.038 1.00 118.58 ? 171 ILE O CB 1 +ATOM 27943 C CG1 . ILE O 1 171 ? 3.952 21.866 41.900 1.00 103.18 ? 171 ILE O CG1 1 +ATOM 27944 C CG2 . ILE O 1 171 ? 2.000 23.191 42.772 1.00 145.34 ? 171 ILE O CG2 1 +ATOM 27945 C CD1 . ILE O 1 171 ? 4.477 22.821 40.853 1.00 125.46 ? 171 ILE O CD1 1 +ATOM 27946 N N . LEU O 1 172 ? 0.195 20.947 44.468 1.00 130.59 ? 172 LEU O N 1 +ATOM 27947 C CA . LEU O 1 172 ? -1.186 21.012 44.928 1.00 105.83 ? 172 LEU O CA 1 +ATOM 27948 C C . LEU O 1 172 ? -1.679 22.463 45.107 1.00 112.37 ? 172 LEU O C 1 +ATOM 27949 O O . LEU O 1 172 ? -2.889 22.733 45.272 1.00 86.33 ? 172 LEU O O 1 +ATOM 27950 C CB . LEU O 1 172 ? -1.355 20.240 46.233 1.00 110.10 ? 172 LEU O CB 1 +ATOM 27951 C CG . LEU O 1 172 ? -1.231 18.704 46.091 1.00 112.40 ? 172 LEU O CG 1 +ATOM 27952 C CD1 . LEU O 1 172 ? -1.546 17.865 47.348 1.00 124.69 ? 172 LEU O CD1 1 +ATOM 27953 C CD2 . LEU O 1 172 ? -1.973 18.162 44.884 1.00 109.25 ? 172 LEU O CD2 1 +ATOM 27954 N N . SER O 1 173 ? -0.736 23.396 45.085 1.00 98.40 ? 173 SER O N 1 +ATOM 27955 C CA . SER O 1 173 ? -1.061 24.799 45.205 1.00 106.02 ? 173 SER O CA 1 +ATOM 27956 C C . SER O 1 173 ? 0.162 25.658 44.907 1.00 106.49 ? 173 SER O C 1 +ATOM 27957 O O . SER O 1 173 ? 1.223 25.467 45.491 1.00 124.51 ? 173 SER O O 1 +ATOM 27958 C CB . SER O 1 173 ? -1.565 25.106 46.623 1.00 124.66 ? 173 SER O CB 1 +ATOM 27959 O OG . SER O 1 173 ? -1.560 26.507 46.871 1.00 180.11 ? 173 SER O OG 1 +ATOM 27960 N N . SER O 1 174 ? -0.018 26.685 44.090 1.00 114.56 ? 174 SER O N 1 +ATOM 27961 C CA . SER O 1 174 ? 0.985 27.749 43.961 1.00 132.67 ? 174 SER O CA 1 +ATOM 27962 C C . SER O 1 174 ? 0.359 29.093 44.304 1.00 142.18 ? 174 SER O C 1 +ATOM 27963 O O . SER O 1 174 ? -0.759 29.392 43.878 1.00 192.02 ? 174 SER O O 1 +ATOM 27964 C CB . SER O 1 174 ? 1.546 27.789 42.531 1.00 147.61 ? 174 SER O CB 1 +ATOM 27965 O OG . SER O 1 174 ? 2.686 28.631 42.408 1.00 148.94 ? 174 SER O OG 1 +ATOM 27966 N N . VAL O 1 175 ? 1.085 29.909 45.062 1.00 139.76 ? 175 VAL O N 1 +ATOM 27967 C CA . VAL O 1 175 ? 0.622 31.258 45.411 1.00 126.62 ? 175 VAL O CA 1 +ATOM 27968 C C . VAL O 1 175 ? 1.723 32.314 45.277 1.00 124.10 ? 175 VAL O C 1 +ATOM 27969 O O . VAL O 1 175 ? 2.905 32.041 45.535 1.00 95.40 ? 175 VAL O O 1 +ATOM 27970 C CB . VAL O 1 175 ? 0.079 31.301 46.848 1.00 136.79 ? 175 VAL O CB 1 +ATOM 27971 C CG1 . VAL O 1 175 ? -1.130 30.392 46.980 1.00 142.30 ? 175 VAL O CG1 1 +ATOM 27972 C CG2 . VAL O 1 175 ? 1.137 30.883 47.848 1.00 132.05 ? 175 VAL O CG2 1 +ATOM 27973 N N . ASN O 1 176 ? 1.330 33.521 44.861 1.00 120.43 ? 176 ASN O N 1 +ATOM 27974 C CA . ASN O 1 176 ? 2.288 34.596 44.513 1.00 122.26 ? 176 ASN O CA 1 +ATOM 27975 C C . ASN O 1 176 ? 2.004 35.899 45.261 1.00 82.79 ? 176 ASN O C 1 +ATOM 27976 O O . ASN O 1 176 ? 1.205 36.683 44.804 1.00 92.65 ? 176 ASN O O 1 +ATOM 27977 C CB . ASN O 1 176 ? 2.217 34.855 42.994 1.00 118.45 ? 176 ASN O CB 1 +ATOM 27978 C CG . ASN O 1 176 ? 3.323 34.154 42.200 1.00 124.53 ? 176 ASN O CG 1 +ATOM 27979 O OD1 . ASN O 1 176 ? 3.580 34.439 41.004 1.00 127.69 ? 176 ASN O OD1 1 +ATOM 27980 N ND2 . ASN O 1 176 ? 3.978 33.217 42.861 1.00 111.95 ? 176 ASN O ND2 1 +ATOM 27981 N N . THR O 1 177 ? 2.638 36.115 46.413 1.00 76.04 ? 177 THR O N 1 +ATOM 27982 C CA . THR O 1 177 ? 2.361 37.291 47.246 1.00 85.00 ? 177 THR O CA 1 +ATOM 27983 C C . THR O 1 177 ? 3.363 38.404 46.957 1.00 109.83 ? 177 THR O C 1 +ATOM 27984 O O . THR O 1 177 ? 4.454 38.148 46.443 1.00 145.56 ? 177 THR O O 1 +ATOM 27985 C CB . THR O 1 177 ? 2.374 36.961 48.757 1.00 91.57 ? 177 THR O CB 1 +ATOM 27986 O OG1 . THR O 1 177 ? 3.707 36.648 49.172 1.00 105.77 ? 177 THR O OG1 1 +ATOM 27987 C CG2 . THR O 1 177 ? 1.472 35.774 49.068 1.00 99.21 ? 177 THR O CG2 1 +ATOM 27988 N N . SER O 1 178 ? 2.997 39.631 47.321 1.00 128.70 ? 178 SER O N 1 +ATOM 27989 C CA . SER O 1 178 ? 3.827 40.811 47.049 1.00 137.98 ? 178 SER O CA 1 +ATOM 27990 C C . SER O 1 178 ? 3.673 41.863 48.142 1.00 140.55 ? 178 SER O C 1 +ATOM 27991 O O . SER O 1 178 ? 2.659 41.929 48.830 1.00 128.85 ? 178 SER O O 1 +ATOM 27992 C CB . SER O 1 178 ? 3.464 41.441 45.704 1.00 125.95 ? 178 SER O CB 1 +ATOM 27993 O OG . SER O 1 178 ? 4.033 42.741 45.581 1.00 120.93 ? 178 SER O OG 1 +ATOM 27994 N N . LYS O 1 179 ? 4.700 42.687 48.304 1.00 138.98 ? 179 LYS O N 1 +ATOM 27995 C CA . LYS O 1 179 ? 4.730 43.617 49.414 1.00 123.49 ? 179 LYS O CA 1 +ATOM 27996 C C . LYS O 1 179 ? 5.632 44.798 49.070 1.00 125.38 ? 179 LYS O C 1 +ATOM 27997 O O . LYS O 1 179 ? 6.671 44.657 48.413 1.00 100.47 ? 179 LYS O O 1 +ATOM 27998 C CB . LYS O 1 179 ? 5.200 42.897 50.686 1.00 114.41 ? 179 LYS O CB 1 +ATOM 27999 C CG . LYS O 1 179 ? 4.533 43.353 51.964 1.00 97.45 ? 179 LYS O CG 1 +ATOM 28000 C CD . LYS O 1 179 ? 5.370 44.420 52.632 1.00 98.87 ? 179 LYS O CD 1 +ATOM 28001 C CE . LYS O 1 179 ? 4.627 45.007 53.809 1.00 125.87 ? 179 LYS O CE 1 +ATOM 28002 N NZ . LYS O 1 179 ? 5.270 46.258 54.292 1.00 148.37 ? 179 LYS O NZ 1 +ATOM 28003 N N . THR O 1 180 ? 5.228 45.965 49.548 1.00 126.72 ? 180 THR O N 1 +ATOM 28004 C CA . THR O 1 180 ? 5.928 47.195 49.236 1.00 138.86 ? 180 THR O CA 1 +ATOM 28005 C C . THR O 1 180 ? 6.722 47.725 50.447 1.00 144.41 ? 180 THR O C 1 +ATOM 28006 O O . THR O 1 180 ? 6.219 47.771 51.581 1.00 73.54 ? 180 THR O O 1 +ATOM 28007 C CB . THR O 1 180 ? 4.964 48.279 48.715 1.00 154.26 ? 180 THR O CB 1 +ATOM 28008 O OG1 . THR O 1 180 ? 5.537 49.572 48.946 1.00 182.31 ? 180 THR O OG1 1 +ATOM 28009 C CG2 . THR O 1 180 ? 3.604 48.178 49.397 1.00 139.48 ? 180 THR O CG2 1 +ATOM 28010 N N . ILE O 1 181 ? 7.983 48.086 50.197 1.00 155.97 ? 181 ILE O N 1 +ATOM 28011 C CA . ILE O 1 181 ? 8.855 48.624 51.242 1.00 137.65 ? 181 ILE O CA 1 +ATOM 28012 C C . ILE O 1 181 ? 8.881 50.152 51.150 1.00 114.88 ? 181 ILE O C 1 +ATOM 28013 O O . ILE O 1 181 ? 9.370 50.710 50.157 1.00 96.17 ? 181 ILE O O 1 +ATOM 28014 C CB . ILE O 1 181 ? 10.290 48.035 51.133 1.00 129.16 ? 181 ILE O CB 1 +ATOM 28015 C CG1 . ILE O 1 181 ? 10.239 46.507 51.112 1.00 139.81 ? 181 ILE O CG1 1 +ATOM 28016 C CG2 . ILE O 1 181 ? 11.163 48.467 52.300 1.00 124.88 ? 181 ILE O CG2 1 +ATOM 28017 C CD1 . ILE O 1 181 ? 10.811 45.908 49.852 1.00 171.90 ? 181 ILE O CD1 1 +ATOM 28018 N N . LEU O 1 182 ? 8.401 50.811 52.206 1.00 98.13 ? 182 LEU O N 1 +ATOM 28019 C CA . LEU O 1 182 ? 8.349 52.279 52.267 1.00 113.85 ? 182 LEU O CA 1 +ATOM 28020 C C . LEU O 1 182 ? 9.574 52.970 52.897 1.00 105.29 ? 182 LEU O C 1 +ATOM 28021 O O . LEU O 1 182 ? 10.117 52.508 53.914 1.00 112.75 ? 182 LEU O O 1 +ATOM 28022 C CB . LEU O 1 182 ? 7.127 52.707 53.056 1.00 123.35 ? 182 LEU O CB 1 +ATOM 28023 C CG . LEU O 1 182 ? 6.937 54.218 53.199 1.00 154.62 ? 182 LEU O CG 1 +ATOM 28024 C CD1 . LEU O 1 182 ? 6.749 54.935 51.860 1.00 167.93 ? 182 LEU O CD1 1 +ATOM 28025 C CD2 . LEU O 1 182 ? 5.755 54.452 54.121 1.00 174.22 ? 182 LEU O CD2 1 +ATOM 28026 N N . SER O 1 183 ? 9.994 54.083 52.290 1.00 91.02 ? 183 SER O N 1 +ATOM 28027 C CA . SER O 1 183 ? 11.080 54.901 52.813 1.00 104.45 ? 183 SER O CA 1 +ATOM 28028 C C . SER O 1 183 ? 10.740 56.371 52.640 1.00 139.35 ? 183 SER O C 1 +ATOM 28029 O O . SER O 1 183 ? 10.184 56.772 51.614 1.00 168.77 ? 183 SER O O 1 +ATOM 28030 C CB . SER O 1 183 ? 12.402 54.593 52.095 1.00 111.31 ? 183 SER O CB 1 +ATOM 28031 O OG . SER O 1 183 ? 12.527 53.202 51.817 1.00 144.94 ? 183 SER O OG 1 +ATOM 28032 N N . TYR O 1 184 ? 11.075 57.182 53.640 1.00 183.17 ? 184 TYR O N 1 +ATOM 28033 C CA . TYR O 1 184 ? 10.875 58.627 53.538 1.00 169.72 ? 184 TYR O CA 1 +ATOM 28034 C C . TYR O 1 184 ? 11.877 59.451 54.348 1.00 171.55 ? 184 TYR O C 1 +ATOM 28035 O O . TYR O 1 184 ? 12.414 59.005 55.368 1.00 134.74 ? 184 TYR O O 1 +ATOM 28036 C CB . TYR O 1 184 ? 9.432 59.002 53.894 1.00 141.39 ? 184 TYR O CB 1 +ATOM 28037 C CG . TYR O 1 184 ? 9.019 58.577 55.286 1.00 143.03 ? 184 TYR O CG 1 +ATOM 28038 C CD1 . TYR O 1 184 ? 9.278 59.383 56.386 1.00 134.70 ? 184 TYR O CD1 1 +ATOM 28039 C CD2 . TYR O 1 184 ? 8.350 57.371 55.497 1.00 141.52 ? 184 TYR O CD2 1 +ATOM 28040 C CE1 . TYR O 1 184 ? 8.871 59.003 57.649 1.00 123.26 ? 184 TYR O CE1 1 +ATOM 28041 C CE2 . TYR O 1 184 ? 7.942 56.980 56.762 1.00 109.05 ? 184 TYR O CE2 1 +ATOM 28042 C CZ . TYR O 1 184 ? 8.211 57.789 57.829 1.00 110.76 ? 184 TYR O CZ 1 +ATOM 28043 O OH . TYR O 1 184 ? 7.780 57.425 59.070 1.00 106.05 ? 184 TYR O OH 1 +ATOM 28044 N N . GLU O 1 185 ? 12.078 60.681 53.883 1.00 212.58 ? 185 GLU O N 1 +ATOM 28045 C CA . GLU O 1 185 ? 13.015 61.630 54.479 1.00 227.11 ? 185 GLU O CA 1 +ATOM 28046 C C . GLU O 1 185 ? 12.379 63.004 54.654 1.00 217.82 ? 185 GLU O C 1 +ATOM 28047 O O . GLU O 1 185 ? 12.089 63.686 53.678 1.00 224.15 ? 185 GLU O O 1 +ATOM 28048 C CB . GLU O 1 185 ? 14.282 61.797 53.639 1.00 204.44 ? 185 GLU O CB 1 +ATOM 28049 C CG . GLU O 1 185 ? 14.854 60.524 53.051 1.00 187.23 ? 185 GLU O CG 1 +ATOM 28050 C CD . GLU O 1 185 ? 16.209 60.777 52.421 1.00 201.84 ? 185 GLU O CD 1 +ATOM 28051 O OE1 . GLU O 1 185 ? 16.659 61.954 52.411 1.00 227.74 ? 185 GLU O OE1 1 +ATOM 28052 O OE2 . GLU O 1 185 ? 16.832 59.803 51.959 1.00 188.48 ? 185 GLU O OE2 1 +ATOM 28053 N N . VAL O 1 186 ? 12.172 63.393 55.907 1.00 162.01 ? 186 VAL O N 1 +ATOM 28054 C CA . VAL O 1 186 ? 11.642 64.694 56.243 1.00 142.75 ? 186 VAL O CA 1 +ATOM 28055 C C . VAL O 1 186 ? 12.780 65.605 56.698 1.00 156.60 ? 186 VAL O C 1 +ATOM 28056 O O . VAL O 1 186 ? 13.655 65.180 57.451 1.00 216.93 ? 186 VAL O O 1 +ATOM 28057 C CB . VAL O 1 186 ? 10.574 64.574 57.349 1.00 131.67 ? 186 VAL O CB 1 +ATOM 28058 C CG1 . VAL O 1 186 ? 9.876 65.912 57.551 1.00 160.92 ? 186 VAL O CG1 1 +ATOM 28059 C CG2 . VAL O 1 186 ? 9.556 63.500 56.999 1.00 118.00 ? 186 VAL O CG2 1 +ATOM 28060 N N . GLN O 1 187 ? 12.751 66.862 56.263 1.00 161.34 ? 187 GLN O N 1 +ATOM 28061 C CA . GLN O 1 187 ? 13.817 67.808 56.584 1.00 154.59 ? 187 GLN O CA 1 +ATOM 28062 C C . GLN O 1 187 ? 13.297 69.228 56.687 1.00 196.25 ? 187 GLN O C 1 +ATOM 28063 O O . GLN O 1 187 ? 12.478 69.657 55.870 1.00 264.18 ? 187 GLN O O 1 +ATOM 28064 C CB . GLN O 1 187 ? 14.876 67.763 55.487 1.00 147.13 ? 187 GLN O CB 1 +ATOM 28065 C CG . GLN O 1 187 ? 15.925 66.688 55.642 1.00 158.63 ? 187 GLN O CG 1 +ATOM 28066 C CD . GLN O 1 187 ? 16.594 66.366 54.320 1.00 186.45 ? 187 GLN O CD 1 +ATOM 28067 O OE1 . GLN O 1 187 ? 16.881 67.269 53.528 1.00 181.67 ? 187 GLN O OE1 1 +ATOM 28068 N NE2 . GLN O 1 187 ? 16.860 65.078 54.074 1.00 210.24 ? 187 GLN O NE2 1 +ATOM 28069 N N . ALA O 1 188 ? 13.796 69.966 57.669 1.00 208.09 ? 188 ALA O N 1 +ATOM 28070 C CA . ALA O 1 188 ? 13.430 71.370 57.822 1.00 217.06 ? 188 ALA O CA 1 +ATOM 28071 C C . ALA O 1 188 ? 14.637 72.189 58.261 1.00 214.10 ? 188 ALA O C 1 +ATOM 28072 O O . ALA O 1 188 ? 15.433 71.730 59.067 1.00 243.75 ? 188 ALA O O 1 +ATOM 28073 C CB . ALA O 1 188 ? 12.280 71.512 58.814 1.00 200.22 ? 188 ALA O CB 1 +ATOM 28074 N N . GLY O 1 189 ? 14.772 73.396 57.721 1.00 192.48 ? 189 GLY O N 1 +ATOM 28075 C CA . GLY O 1 189 ? 15.883 74.270 58.070 1.00 178.41 ? 189 GLY O CA 1 +ATOM 28076 C C . GLY O 1 189 ? 15.501 75.738 58.104 1.00 192.41 ? 189 GLY O C 1 +ATOM 28077 O O . GLY O 1 189 ? 14.745 76.217 57.258 1.00 209.89 ? 189 GLY O O 1 +ATOM 28078 N N . VAL O 1 190 ? 16.011 76.455 59.098 1.00 208.79 ? 190 VAL O N 1 +ATOM 28079 C CA . VAL O 1 190 ? 15.783 77.892 59.206 1.00 201.97 ? 190 VAL O CA 1 +ATOM 28080 C C . VAL O 1 190 ? 17.110 78.630 58.998 1.00 199.78 ? 190 VAL O C 1 +ATOM 28081 O O . VAL O 1 190 ? 18.142 78.235 59.552 1.00 214.86 ? 190 VAL O O 1 +ATOM 28082 C CB . VAL O 1 190 ? 15.165 78.261 60.574 1.00 182.54 ? 190 VAL O CB 1 +ATOM 28083 C CG1 . VAL O 1 190 ? 14.708 79.713 60.574 1.00 168.34 ? 190 VAL O CG1 1 +ATOM 28084 C CG2 . VAL O 1 190 ? 14.008 77.319 60.917 1.00 141.66 ? 190 VAL O CG2 1 +ATOM 28085 N N . PHE O 1 191 ? 17.083 79.697 58.198 1.00 193.12 ? 191 PHE O N 1 +ATOM 28086 C CA . PHE O 1 191 ? 18.316 80.371 57.779 1.00 185.76 ? 191 PHE O CA 1 +ATOM 28087 C C . PHE O 1 191 ? 18.206 81.884 57.931 1.00 174.81 ? 191 PHE O C 1 +ATOM 28088 O O . PHE O 1 191 ? 17.207 82.476 57.527 1.00 191.63 ? 191 PHE O O 1 +ATOM 28089 C CB . PHE O 1 191 ? 18.637 80.008 56.324 1.00 175.97 ? 191 PHE O CB 1 +ATOM 28090 C CG . PHE O 1 191 ? 20.075 80.209 55.948 1.00 188.18 ? 191 PHE O CG 1 +ATOM 28091 C CD1 . PHE O 1 191 ? 20.592 81.486 55.773 1.00 173.57 ? 191 PHE O CD1 1 +ATOM 28092 C CD2 . PHE O 1 191 ? 20.919 79.120 55.762 1.00 198.63 ? 191 PHE O CD2 1 +ATOM 28093 C CE1 . PHE O 1 191 ? 21.924 81.677 55.426 1.00 154.68 ? 191 PHE O CE1 1 +ATOM 28094 C CE2 . PHE O 1 191 ? 22.255 79.306 55.429 1.00 190.31 ? 191 PHE O CE2 1 +ATOM 28095 C CZ . PHE O 1 191 ? 22.758 80.587 55.257 1.00 143.50 ? 191 PHE O CZ 1 +ATOM 28096 N N . LEU O 1 200 ? 22.496 83.074 61.517 1.00 108.39 ? 200 LEU O N 1 +ATOM 28097 C CA . LEU O 1 200 ? 21.607 82.067 62.100 1.00 152.40 ? 200 LEU O CA 1 +ATOM 28098 C C . LEU O 1 200 ? 21.261 81.012 61.074 1.00 193.97 ? 200 LEU O C 1 +ATOM 28099 O O . LEU O 1 200 ? 20.492 81.269 60.136 1.00 222.56 ? 200 LEU O O 1 +ATOM 28100 C CB . LEU O 1 200 ? 20.286 82.638 62.675 1.00 141.73 ? 200 LEU O CB 1 +ATOM 28101 C CG . LEU O 1 200 ? 19.267 81.561 63.127 1.00 126.96 ? 200 LEU O CG 1 +ATOM 28102 C CD1 . LEU O 1 200 ? 19.315 81.384 64.643 1.00 137.74 ? 200 LEU O CD1 1 +ATOM 28103 C CD2 . LEU O 1 200 ? 17.839 81.832 62.653 1.00 103.39 ? 200 LEU O CD2 1 +ATOM 28104 N N . GLU O 1 201 ? 21.776 79.806 61.298 1.00 215.27 ? 201 GLU O N 1 +ATOM 28105 C CA . GLU O 1 201 ? 21.240 78.608 60.661 1.00 203.06 ? 201 GLU O CA 1 +ATOM 28106 C C . GLU O 1 201 ? 20.771 77.602 61.713 1.00 174.39 ? 201 GLU O C 1 +ATOM 28107 O O . GLU O 1 201 ? 21.340 77.527 62.796 1.00 125.90 ? 201 GLU O O 1 +ATOM 28108 C CB . GLU O 1 201 ? 22.291 77.972 59.755 1.00 188.96 ? 201 GLU O CB 1 +ATOM 28109 C CG . GLU O 1 201 ? 21.689 77.043 58.714 1.00 184.04 ? 201 GLU O CG 1 +ATOM 28110 C CD . GLU O 1 201 ? 22.730 76.415 57.805 1.00 194.56 ? 201 GLU O CD 1 +ATOM 28111 O OE1 . GLU O 1 201 ? 23.570 77.155 57.245 1.00 190.03 ? 201 GLU O OE1 1 +ATOM 28112 O OE2 . GLU O 1 201 ? 22.697 75.177 57.633 1.00 208.12 ? 201 GLU O OE2 1 +ATOM 28113 N N . GLY O 1 202 ? 19.731 76.839 61.383 1.00 164.37 ? 202 GLY O N 1 +ATOM 28114 C CA . GLY O 1 202 ? 19.276 75.732 62.221 1.00 167.82 ? 202 GLY O CA 1 +ATOM 28115 C C . GLY O 1 202 ? 18.559 74.665 61.410 1.00 174.34 ? 202 GLY O C 1 +ATOM 28116 O O . GLY O 1 202 ? 17.639 74.970 60.655 1.00 209.09 ? 202 GLY O O 1 +ATOM 28117 N N . GLU O 1 203 ? 18.994 73.412 61.537 1.00 164.15 ? 203 GLU O N 1 +ATOM 28118 C CA . GLU O 1 203 ? 18.446 72.328 60.721 1.00 165.23 ? 203 GLU O CA 1 +ATOM 28119 C C . GLU O 1 203 ? 18.020 71.105 61.525 1.00 156.96 ? 203 GLU O C 1 +ATOM 28120 O O . GLU O 1 203 ? 18.736 70.650 62.416 1.00 193.00 ? 203 GLU O O 1 +ATOM 28121 C CB . GLU O 1 203 ? 19.459 71.912 59.656 1.00 175.25 ? 203 GLU O CB 1 +ATOM 28122 C CG . GLU O 1 203 ? 19.707 72.995 58.606 1.00 194.87 ? 203 GLU O CG 1 +ATOM 28123 C CD . GLU O 1 203 ? 20.624 72.565 57.467 1.00 195.11 ? 203 GLU O CD 1 +ATOM 28124 O OE1 . GLU O 1 203 ? 21.231 71.475 57.565 1.00 166.99 ? 203 GLU O OE1 1 +ATOM 28125 O OE2 . GLU O 1 203 ? 20.764 73.343 56.488 1.00 205.57 ? 203 GLU O OE2 1 +ATOM 28126 N N . VAL O 1 204 ? 16.852 70.571 61.178 1.00 158.19 ? 204 VAL O N 1 +ATOM 28127 C CA . VAL O 1 204 ? 16.355 69.300 61.705 1.00 176.52 ? 204 VAL O CA 1 +ATOM 28128 C C . VAL O 1 204 ? 16.073 68.343 60.537 1.00 186.32 ? 204 VAL O C 1 +ATOM 28129 O O . VAL O 1 204 ? 15.502 68.743 59.522 1.00 170.83 ? 204 VAL O O 1 +ATOM 28130 C CB . VAL O 1 204 ? 15.079 69.512 62.564 1.00 145.03 ? 204 VAL O CB 1 +ATOM 28131 C CG1 . VAL O 1 204 ? 14.336 68.202 62.813 1.00 140.10 ? 204 VAL O CG1 1 +ATOM 28132 C CG2 . VAL O 1 204 ? 15.449 70.172 63.882 1.00 125.13 ? 204 VAL O CG2 1 +ATOM 28133 N N . GLY O 1 205 ? 16.484 67.084 60.695 1.00 174.14 ? 205 GLY O N 1 +ATOM 28134 C CA . GLY O 1 205 ? 16.205 66.047 59.710 1.00 143.53 ? 205 GLY O CA 1 +ATOM 28135 C C . GLY O 1 205 ? 15.766 64.730 60.339 1.00 129.25 ? 205 GLY O C 1 +ATOM 28136 O O . GLY O 1 205 ? 16.137 64.417 61.468 1.00 129.75 ? 205 GLY O O 1 +ATOM 28137 N N . TYR O 1 206 ? 14.964 63.960 59.604 1.00 126.18 ? 206 TYR O N 1 +ATOM 28138 C CA . TYR O 1 206 ? 14.566 62.608 60.012 1.00 116.74 ? 206 TYR O CA 1 +ATOM 28139 C C . TYR O 1 206 ? 14.368 61.717 58.794 1.00 130.20 ? 206 TYR O C 1 +ATOM 28140 O O . TYR O 1 206 ? 13.841 62.165 57.782 1.00 197.71 ? 206 TYR O O 1 +ATOM 28141 C CB . TYR O 1 206 ? 13.261 62.641 60.806 1.00 100.07 ? 206 TYR O CB 1 +ATOM 28142 C CG . TYR O 1 206 ? 12.743 61.262 61.197 1.00 91.60 ? 206 TYR O CG 1 +ATOM 28143 C CD1 . TYR O 1 206 ? 13.322 60.547 62.251 1.00 98.74 ? 206 TYR O CD1 1 +ATOM 28144 C CD2 . TYR O 1 206 ? 11.653 60.699 60.557 1.00 75.87 ? 206 TYR O CD2 1 +ATOM 28145 C CE1 . TYR O 1 206 ? 12.824 59.314 62.645 1.00 92.75 ? 206 TYR O CE1 1 +ATOM 28146 C CE2 . TYR O 1 206 ? 11.144 59.474 60.952 1.00 84.82 ? 206 TYR O CE2 1 +ATOM 28147 C CZ . TYR O 1 206 ? 11.733 58.775 61.991 1.00 86.87 ? 206 TYR O CZ 1 +ATOM 28148 O OH . TYR O 1 206 ? 11.235 57.525 62.347 1.00 77.95 ? 206 TYR O OH 1 +ATOM 28149 N N . THR O 1 207 ? 14.767 60.452 58.890 1.00 112.90 ? 207 THR O N 1 +ATOM 28150 C CA . THR O 1 207 ? 14.573 59.498 57.787 1.00 91.78 ? 207 THR O CA 1 +ATOM 28151 C C . THR O 1 207 ? 14.080 58.153 58.327 1.00 72.53 ? 207 THR O C 1 +ATOM 28152 O O . THR O 1 207 ? 14.596 57.658 59.342 1.00 76.65 ? 207 THR O O 1 +ATOM 28153 C CB . THR O 1 207 ? 15.879 59.298 56.969 1.00 81.05 ? 207 THR O CB 1 +ATOM 28154 O OG1 . THR O 1 207 ? 16.891 58.757 57.815 1.00 91.43 ? 207 THR O OG1 1 +ATOM 28155 C CG2 . THR O 1 207 ? 16.372 60.599 56.400 1.00 74.20 ? 207 THR O CG2 1 +ATOM 28156 N N . SER O 1 208 ? 13.109 57.548 57.648 1.00 66.88 ? 208 SER O N 1 +ATOM 28157 C CA . SER O 1 208 ? 12.619 56.222 58.053 1.00 102.45 ? 208 SER O CA 1 +ATOM 28158 C C . SER O 1 208 ? 12.515 55.238 56.889 1.00 139.67 ? 208 SER O C 1 +ATOM 28159 O O . SER O 1 208 ? 11.886 55.532 55.879 1.00 155.08 ? 208 SER O O 1 +ATOM 28160 C CB . SER O 1 208 ? 11.265 56.318 58.749 1.00 92.42 ? 208 SER O CB 1 +ATOM 28161 O OG . SER O 1 208 ? 10.744 55.023 59.025 1.00 63.89 ? 208 SER O OG 1 +ATOM 28162 N N . ASN O 1 209 ? 13.160 54.077 57.052 1.00 133.18 ? 209 ASN O N 1 +ATOM 28163 C CA . ASN O 1 209 ? 13.070 52.969 56.108 1.00 83.94 ? 209 ASN O CA 1 +ATOM 28164 C C . ASN O 1 209 ? 12.340 51.822 56.756 1.00 92.58 ? 209 ASN O C 1 +ATOM 28165 O O . ASN O 1 209 ? 12.626 51.450 57.893 1.00 108.92 ? 209 ASN O O 1 +ATOM 28166 C CB . ASN O 1 209 ? 14.453 52.484 55.700 1.00 67.07 ? 209 ASN O CB 1 +ATOM 28167 C CG . ASN O 1 209 ? 15.174 53.464 54.843 1.00 68.71 ? 209 ASN O CG 1 +ATOM 28168 O OD1 . ASN O 1 209 ? 14.951 53.538 53.623 1.00 111.15 ? 209 ASN O OD1 1 +ATOM 28169 N ND2 . ASN O 1 209 ? 16.062 54.228 55.456 1.00 63.36 ? 209 ASN O ND2 1 +ATOM 28170 N N . GLU O 1 210 ? 11.452 51.199 56.003 1.00 117.34 ? 210 GLU O N 1 +ATOM 28171 C CA . GLU O 1 210 ? 10.945 49.890 56.398 1.00 146.64 ? 210 GLU O CA 1 +ATOM 28172 C C . GLU O 1 210 ? 12.091 48.859 56.316 1.00 136.54 ? 210 GLU O C 1 +ATOM 28173 O O . GLU O 1 210 ? 12.902 48.899 55.395 1.00 147.92 ? 210 GLU O O 1 +ATOM 28174 C CB . GLU O 1 210 ? 9.780 49.482 55.485 1.00 159.32 ? 210 GLU O CB 1 +ATOM 28175 C CG . GLU O 1 210 ? 8.571 48.907 56.201 1.00 134.68 ? 210 GLU O CG 1 +ATOM 28176 C CD . GLU O 1 210 ? 7.325 48.920 55.322 1.00 117.50 ? 210 GLU O CD 1 +ATOM 28177 O OE1 . GLU O 1 210 ? 7.198 49.770 54.396 1.00 69.18 ? 210 GLU O OE1 1 +ATOM 28178 O OE2 . GLU O 1 210 ? 6.455 48.069 55.588 1.00 128.93 ? 210 GLU O OE2 1 +ATOM 28179 N N . PRO O 1 211 ? 12.164 47.937 57.279 1.00 105.25 ? 211 PRO O N 1 +ATOM 28180 C CA . PRO O 1 211 ? 13.070 46.815 57.127 1.00 115.55 ? 211 PRO O CA 1 +ATOM 28181 C C . PRO O 1 211 ? 12.607 45.837 56.027 1.00 146.87 ? 211 PRO O C 1 +ATOM 28182 O O . PRO O 1 211 ? 11.472 45.331 56.069 1.00 182.67 ? 211 PRO O O 1 +ATOM 28183 C CB . PRO O 1 211 ? 13.044 46.150 58.512 1.00 94.32 ? 211 PRO O CB 1 +ATOM 28184 C CG . PRO O 1 211 ? 12.473 47.166 59.418 1.00 96.04 ? 211 PRO O CG 1 +ATOM 28185 C CD . PRO O 1 211 ? 11.483 47.911 58.573 1.00 99.25 ? 211 PRO O CD 1 +ATOM 28186 N N . VAL O 1 212 ? 13.483 45.582 55.056 1.00 123.78 ? 212 VAL O N 1 +ATOM 28187 C CA . VAL O 1 212 ? 13.205 44.629 53.990 1.00 103.08 ? 212 VAL O CA 1 +ATOM 28188 C C . VAL O 1 212 ? 13.021 43.237 54.594 1.00 108.36 ? 212 VAL O C 1 +ATOM 28189 O O . VAL O 1 212 ? 12.137 42.465 54.204 1.00 129.23 ? 212 VAL O O 1 +ATOM 28190 C CB . VAL O 1 212 ? 14.368 44.575 52.984 1.00 117.17 ? 212 VAL O CB 1 +ATOM 28191 C CG1 . VAL O 1 212 ? 14.001 43.675 51.802 1.00 146.32 ? 212 VAL O CG1 1 +ATOM 28192 C CG2 . VAL O 1 212 ? 14.750 45.971 52.498 1.00 101.68 ? 212 VAL O CG2 1 +ATOM 28193 N N . MET O 1 213 ? 13.910 42.918 55.525 1.00 109.21 ? 213 MET O N 1 +ATOM 28194 C CA . MET O 1 213 ? 13.761 41.823 56.475 1.00 116.47 ? 213 MET O CA 1 +ATOM 28195 C C . MET O 1 213 ? 12.297 41.541 56.903 1.00 110.52 ? 213 MET O C 1 +ATOM 28196 O O . MET O 1 213 ? 11.792 40.406 56.839 1.00 93.57 ? 213 MET O O 1 +ATOM 28197 C CB . MET O 1 213 ? 14.608 42.244 57.683 1.00 123.51 ? 213 MET O CB 1 +ATOM 28198 C CG . MET O 1 213 ? 14.761 41.263 58.810 1.00 155.56 ? 213 MET O CG 1 +ATOM 28199 S SD . MET O 1 213 ? 15.815 42.043 60.044 1.00 161.12 ? 213 MET O SD 1 +ATOM 28200 C CE . MET O 1 213 ? 14.557 42.281 61.289 1.00 188.74 ? 213 MET O CE 1 +ATOM 28201 N N . LEU O 1 214 ? 11.627 42.595 57.338 1.00 114.98 ? 214 LEU O N 1 +ATOM 28202 C CA . LEU O 1 214 ? 10.357 42.472 58.028 1.00 139.24 ? 214 LEU O CA 1 +ATOM 28203 C C . LEU O 1 214 ? 9.244 42.337 56.995 1.00 146.68 ? 214 LEU O C 1 +ATOM 28204 O O . LEU O 1 214 ? 8.191 41.752 57.259 1.00 195.00 ? 214 LEU O O 1 +ATOM 28205 C CB . LEU O 1 214 ? 10.143 43.702 58.929 1.00 169.26 ? 214 LEU O CB 1 +ATOM 28206 C CG . LEU O 1 214 ? 9.583 43.506 60.342 1.00 184.35 ? 214 LEU O CG 1 +ATOM 28207 C CD1 . LEU O 1 214 ? 10.464 42.606 61.198 1.00 165.69 ? 214 LEU O CD1 1 +ATOM 28208 C CD2 . LEU O 1 214 ? 9.406 44.863 61.015 1.00 204.80 ? 214 LEU O CD2 1 +ATOM 28209 N N . CYS O 1 215 ? 9.460 42.935 55.827 1.00 126.88 ? 215 CYS O N 1 +ATOM 28210 C CA . CYS O 1 215 ? 8.488 42.867 54.730 1.00 129.67 ? 215 CYS O CA 1 +ATOM 28211 C C . CYS O 1 215 ? 8.476 41.464 54.138 1.00 131.69 ? 215 CYS O C 1 +ATOM 28212 O O . CYS O 1 215 ? 7.427 40.916 53.765 1.00 96.57 ? 215 CYS O O 1 +ATOM 28213 C CB . CYS O 1 215 ? 8.857 43.874 53.638 1.00 123.35 ? 215 CYS O CB 1 +ATOM 28214 S SG . CYS O 1 215 ? 8.726 45.586 54.157 1.00 139.21 ? 215 CYS O SG 1 +ATOM 28215 N N . LEU O 1 216 ? 9.677 40.912 54.003 1.00 144.60 ? 216 LEU O N 1 +ATOM 28216 C CA . LEU O 1 216 ? 9.821 39.549 53.547 1.00 130.84 ? 216 LEU O CA 1 +ATOM 28217 C C . LEU O 1 216 ? 9.027 38.647 54.487 1.00 114.81 ? 216 LEU O C 1 +ATOM 28218 O O . LEU O 1 216 ? 8.252 37.797 54.033 1.00 113.95 ? 216 LEU O O 1 +ATOM 28219 C CB . LEU O 1 216 ? 11.306 39.140 53.509 1.00 140.94 ? 216 LEU O CB 1 +ATOM 28220 C CG . LEU O 1 216 ? 11.588 37.689 53.093 1.00 122.14 ? 216 LEU O CG 1 +ATOM 28221 C CD1 . LEU O 1 216 ? 10.997 37.357 51.725 1.00 124.10 ? 216 LEU O CD1 1 +ATOM 28222 C CD2 . LEU O 1 216 ? 13.075 37.405 53.100 1.00 95.69 ? 216 LEU O CD2 1 +ATOM 28223 N N . MET O 1 217 ? 9.223 38.841 55.791 1.00 94.40 ? 217 MET O N 1 +ATOM 28224 C CA . MET O 1 217 ? 8.611 37.969 56.776 1.00 93.90 ? 217 MET O CA 1 +ATOM 28225 C C . MET O 1 217 ? 7.084 38.074 56.684 1.00 122.92 ? 217 MET O C 1 +ATOM 28226 O O . MET O 1 217 ? 6.384 37.059 56.619 1.00 121.34 ? 217 MET O O 1 +ATOM 28227 C CB . MET O 1 217 ? 9.100 38.319 58.179 1.00 83.16 ? 217 MET O CB 1 +ATOM 28228 C CG . MET O 1 217 ? 9.401 37.091 59.024 1.00 100.84 ? 217 MET O CG 1 +ATOM 28229 S SD . MET O 1 217 ? 7.910 36.157 59.473 1.00 157.59 ? 217 MET O SD 1 +ATOM 28230 C CE . MET O 1 217 ? 8.593 34.662 60.203 1.00 141.57 ? 217 MET O CE 1 +ATOM 28231 N N . SER O 1 218 ? 6.585 39.308 56.612 1.00 133.74 ? 218 SER O N 1 +ATOM 28232 C CA . SER O 1 218 ? 5.156 39.569 56.469 1.00 113.14 ? 218 SER O CA 1 +ATOM 28233 C C . SER O 1 218 ? 4.563 38.849 55.255 1.00 131.91 ? 218 SER O C 1 +ATOM 28234 O O . SER O 1 218 ? 3.538 38.154 55.355 1.00 137.48 ? 218 SER O O 1 +ATOM 28235 C CB . SER O 1 218 ? 4.917 41.068 56.326 1.00 117.57 ? 218 SER O CB 1 +ATOM 28236 O OG . SER O 1 218 ? 3.530 41.376 56.423 1.00 186.10 ? 218 SER O OG 1 +ATOM 28237 N N . ALA O 1 219 ? 5.200 39.026 54.102 1.00 141.88 ? 219 ALA O N 1 +ATOM 28238 C CA . ALA O 1 219 ? 4.687 38.463 52.854 1.00 139.27 ? 219 ALA O CA 1 +ATOM 28239 C C . ALA O 1 219 ? 4.657 36.916 52.883 1.00 124.55 ? 219 ALA O C 1 +ATOM 28240 O O . ALA O 1 219 ? 3.758 36.277 52.324 1.00 82.88 ? 219 ALA O O 1 +ATOM 28241 C CB . ALA O 1 219 ? 5.522 38.973 51.690 1.00 136.86 ? 219 ALA O CB 1 +ATOM 28242 N N . ILE O 1 220 ? 5.636 36.318 53.557 1.00 123.93 ? 220 ILE O N 1 +ATOM 28243 C CA . ILE O 1 220 ? 5.696 34.863 53.666 1.00 104.92 ? 220 ILE O CA 1 +ATOM 28244 C C . ILE O 1 220 ? 4.523 34.360 54.512 1.00 116.21 ? 220 ILE O C 1 +ATOM 28245 O O . ILE O 1 220 ? 3.901 33.339 54.196 1.00 73.00 ? 220 ILE O O 1 +ATOM 28246 C CB . ILE O 1 220 ? 7.055 34.390 54.245 1.00 82.66 ? 220 ILE O CB 1 +ATOM 28247 C CG1 . ILE O 1 220 ? 8.155 34.633 53.208 1.00 74.93 ? 220 ILE O CG1 1 +ATOM 28248 C CG2 . ILE O 1 220 ? 6.992 32.912 54.644 1.00 67.49 ? 220 ILE O CG2 1 +ATOM 28249 C CD1 . ILE O 1 220 ? 9.550 34.574 53.776 1.00 96.62 ? 220 ILE O CD1 1 +ATOM 28250 N N . GLU O 1 221 ? 4.230 35.069 55.598 1.00 133.04 ? 221 GLU O N 1 +ATOM 28251 C CA . GLU O 1 221 ? 3.097 34.711 56.457 1.00 142.63 ? 221 GLU O CA 1 +ATOM 28252 C C . GLU O 1 221 ? 1.806 34.713 55.637 1.00 135.61 ? 221 GLU O C 1 +ATOM 28253 O O . GLU O 1 221 ? 1.032 33.749 55.661 1.00 115.12 ? 221 GLU O O 1 +ATOM 28254 C CB . GLU O 1 221 ? 2.995 35.695 57.633 1.00 156.62 ? 221 GLU O CB 1 +ATOM 28255 C CG . GLU O 1 221 ? 4.050 35.488 58.711 1.00 178.76 ? 221 GLU O CG 1 +ATOM 28256 C CD . GLU O 1 221 ? 4.199 36.679 59.654 1.00 174.25 ? 221 GLU O CD 1 +ATOM 28257 O OE1 . GLU O 1 221 ? 4.126 37.851 59.193 1.00 118.68 ? 221 GLU O OE1 1 +ATOM 28258 O OE2 . GLU O 1 221 ? 4.501 36.413 60.841 1.00 145.17 ? 221 GLU O OE2 1 +ATOM 28259 N N . THR O 1 222 ? 1.594 35.819 54.924 1.00 119.42 ? 222 THR O N 1 +ATOM 28260 C CA . THR O 1 222 ? 0.433 36.001 54.055 1.00 100.88 ? 222 THR O CA 1 +ATOM 28261 C C . THR O 1 222 ? 0.300 34.833 53.090 1.00 109.35 ? 222 THR O C 1 +ATOM 28262 O O . THR O 1 222 ? -0.791 34.279 52.927 1.00 113.27 ? 222 THR O O 1 +ATOM 28263 C CB . THR O 1 222 ? 0.583 37.296 53.238 1.00 96.30 ? 222 THR O CB 1 +ATOM 28264 O OG1 . THR O 1 222 ? 0.415 38.439 54.101 1.00 94.10 ? 222 THR O OG1 1 +ATOM 28265 C CG2 . THR O 1 222 ? -0.406 37.337 52.044 1.00 80.02 ? 222 THR O CG2 1 +ATOM 28266 N N . GLY O 1 223 ? 1.413 34.480 52.446 1.00 105.35 ? 223 GLY O N 1 +ATOM 28267 C CA . GLY O 1 223 ? 1.462 33.327 51.551 1.00 92.56 ? 223 GLY O CA 1 +ATOM 28268 C C . GLY O 1 223 ? 1.046 32.030 52.224 1.00 91.87 ? 223 GLY O C 1 +ATOM 28269 O O . GLY O 1 223 ? 0.309 31.218 51.634 1.00 79.88 ? 223 GLY O O 1 +ATOM 28270 N N . VAL O 1 224 ? 1.453 31.853 53.484 1.00 75.48 ? 224 VAL O N 1 +ATOM 28271 C CA . VAL O 1 224 ? 1.089 30.647 54.217 1.00 95.82 ? 224 VAL O CA 1 +ATOM 28272 C C . VAL O 1 224 ? -0.428 30.591 54.432 1.00 108.85 ? 224 VAL O C 1 +ATOM 28273 O O . VAL O 1 224 ? -1.057 29.533 54.273 1.00 85.22 ? 224 VAL O O 1 +ATOM 28274 C CB . VAL O 1 224 ? 1.796 30.564 55.581 1.00 100.89 ? 224 VAL O CB 1 +ATOM 28275 C CG1 . VAL O 1 224 ? 1.251 29.385 56.388 1.00 109.70 ? 224 VAL O CG1 1 +ATOM 28276 C CG2 . VAL O 1 224 ? 3.293 30.431 55.394 1.00 87.74 ? 224 VAL O CG2 1 +ATOM 28277 N N . ILE O 1 225 ? -1.020 31.736 54.774 1.00 115.34 ? 225 ILE O N 1 +ATOM 28278 C CA . ILE O 1 225 ? -2.472 31.805 54.951 1.00 136.34 ? 225 ILE O CA 1 +ATOM 28279 C C . ILE O 1 225 ? -3.209 31.439 53.661 1.00 136.38 ? 225 ILE O C 1 +ATOM 28280 O O . ILE O 1 225 ? -4.052 30.540 53.677 1.00 111.21 ? 225 ILE O O 1 +ATOM 28281 C CB . ILE O 1 225 ? -2.934 33.191 55.421 1.00 160.18 ? 225 ILE O CB 1 +ATOM 28282 C CG1 . ILE O 1 225 ? -2.440 33.457 56.843 1.00 178.26 ? 225 ILE O CG1 1 +ATOM 28283 C CG2 . ILE O 1 225 ? -4.451 33.273 55.397 1.00 168.75 ? 225 ILE O CG2 1 +ATOM 28284 C CD1 . ILE O 1 225 ? -2.471 34.920 57.235 1.00 190.14 ? 225 ILE O CD1 1 +ATOM 28285 N N . PHE O 1 226 ? -2.850 32.093 52.550 1.00 130.42 ? 226 PHE O N 1 +ATOM 28286 C CA . PHE O 1 226 ? -3.432 31.771 51.243 1.00 123.73 ? 226 PHE O CA 1 +ATOM 28287 C C . PHE O 1 226 ? -3.285 30.280 50.888 1.00 128.63 ? 226 PHE O C 1 +ATOM 28288 O O . PHE O 1 226 ? -4.163 29.703 50.239 1.00 122.67 ? 226 PHE O O 1 +ATOM 28289 C CB . PHE O 1 226 ? -2.819 32.626 50.126 1.00 120.50 ? 226 PHE O CB 1 +ATOM 28290 C CG . PHE O 1 226 ? -3.376 34.037 50.040 1.00 124.32 ? 226 PHE O CG 1 +ATOM 28291 C CD1 . PHE O 1 226 ? -4.722 34.264 49.781 1.00 97.44 ? 226 PHE O CD1 1 +ATOM 28292 C CD2 . PHE O 1 226 ? -2.512 35.135 50.101 1.00 134.42 ? 226 PHE O CD2 1 +ATOM 28293 C CE1 . PHE O 1 226 ? -5.209 35.549 49.684 1.00 90.11 ? 226 PHE O CE1 1 +ATOM 28294 C CE2 . PHE O 1 226 ? -2.985 36.423 49.946 1.00 105.38 ? 226 PHE O CE2 1 +ATOM 28295 C CZ . PHE O 1 226 ? -4.342 36.631 49.767 1.00 104.44 ? 226 PHE O CZ 1 +ATOM 28296 N N . LEU O 1 227 ? -2.183 29.660 51.308 1.00 128.29 ? 227 LEU O N 1 +ATOM 28297 C CA . LEU O 1 227 ? -1.986 28.219 51.090 1.00 125.57 ? 227 LEU O CA 1 +ATOM 28298 C C . LEU O 1 227 ? -2.989 27.418 51.861 1.00 119.45 ? 227 LEU O C 1 +ATOM 28299 O O . LEU O 1 227 ? -3.533 26.447 51.336 1.00 178.78 ? 227 LEU O O 1 +ATOM 28300 C CB . LEU O 1 227 ? -0.607 27.735 51.544 1.00 124.51 ? 227 LEU O CB 1 +ATOM 28301 C CG . LEU O 1 227 ? 0.351 27.189 50.489 1.00 123.47 ? 227 LEU O CG 1 +ATOM 28302 C CD1 . LEU O 1 227 ? 0.057 27.880 49.205 1.00 125.36 ? 227 LEU O CD1 1 +ATOM 28303 C CD2 . LEU O 1 227 ? 1.851 27.243 50.763 1.00 119.34 ? 227 LEU O CD2 1 +ATOM 28304 N N . ILE O 1 228 ? -3.161 27.759 53.135 1.00 115.49 ? 228 ILE O N 1 +ATOM 28305 C CA . ILE O 1 228 ? -4.051 26.997 54.007 1.00 132.51 ? 228 ILE O CA 1 +ATOM 28306 C C . ILE O 1 228 ? -5.478 27.127 53.491 1.00 149.81 ? 228 ILE O C 1 +ATOM 28307 O O . ILE O 1 228 ? -6.191 26.129 53.354 1.00 152.34 ? 228 ILE O O 1 +ATOM 28308 C CB . ILE O 1 228 ? -4.004 27.469 55.476 1.00 114.24 ? 228 ILE O CB 1 +ATOM 28309 C CG1 . ILE O 1 228 ? -2.623 27.229 56.079 1.00 106.92 ? 228 ILE O CG1 1 +ATOM 28310 C CG2 . ILE O 1 228 ? -5.031 26.713 56.301 1.00 95.84 ? 228 ILE O CG2 1 +ATOM 28311 C CD1 . ILE O 1 228 ? -2.367 27.978 57.367 1.00 101.38 ? 228 ILE O CD1 1 +ATOM 28312 N N . ASN O 1 229 ? -5.876 28.356 53.178 1.00 140.91 ? 229 ASN O N 1 +ATOM 28313 C CA . ASN O 1 229 ? -7.224 28.624 52.686 1.00 145.38 ? 229 ASN O CA 1 +ATOM 28314 C C . ASN O 1 229 ? -7.483 27.897 51.372 1.00 124.72 ? 229 ASN O C 1 +ATOM 28315 O O . ASN O 1 229 ? -8.520 27.246 51.211 1.00 121.81 ? 229 ASN O O 1 +ATOM 28316 C CB . ASN O 1 229 ? -7.421 30.129 52.496 1.00 164.35 ? 229 ASN O CB 1 +ATOM 28317 C CG . ASN O 1 229 ? -8.877 30.518 52.371 1.00 164.08 ? 229 ASN O CG 1 +ATOM 28318 O OD1 . ASN O 1 229 ? -9.773 29.813 52.847 1.00 157.93 ? 229 ASN O OD1 1 +ATOM 28319 N ND2 . ASN O 1 229 ? -9.121 31.665 51.755 1.00 170.08 ? 229 ASN O ND2 1 +ATOM 28320 N N . ASP O 1 230 ? -6.503 27.959 50.472 1.00 102.86 ? 230 ASP O N 1 +ATOM 28321 C CA . ASP O 1 230 ? -6.562 27.231 49.207 1.00 113.74 ? 230 ASP O CA 1 +ATOM 28322 C C . ASP O 1 230 ? -6.702 25.713 49.427 1.00 112.42 ? 230 ASP O C 1 +ATOM 28323 O O . ASP O 1 230 ? -7.497 25.045 48.758 1.00 106.06 ? 230 ASP O O 1 +ATOM 28324 C CB . ASP O 1 230 ? -5.310 27.516 48.367 1.00 111.65 ? 230 ASP O CB 1 +ATOM 28325 C CG . ASP O 1 230 ? -5.390 26.928 46.968 1.00 119.93 ? 230 ASP O CG 1 +ATOM 28326 O OD1 . ASP O 1 230 ? -6.175 27.454 46.157 1.00 180.29 ? 230 ASP O OD1 1 +ATOM 28327 O OD2 . ASP O 1 230 ? -4.737 25.910 46.684 1.00 108.40 ? 230 ASP O OD2 1 +ATOM 28328 N N . GLY O 1 231 ? -5.959 25.182 50.391 1.00 125.68 ? 231 GLY O N 1 +ATOM 28329 C CA . GLY O 1 231 ? -6.016 23.757 50.705 1.00 136.58 ? 231 GLY O CA 1 +ATOM 28330 C C . GLY O 1 231 ? -7.339 23.339 51.333 1.00 135.94 ? 231 GLY O C 1 +ATOM 28331 O O . GLY O 1 231 ? -7.848 22.238 51.054 1.00 142.64 ? 231 GLY O O 1 +ATOM 28332 N N . ILE O 1 232 ? -7.928 24.242 52.121 1.00 116.54 ? 232 ILE O N 1 +ATOM 28333 C CA . ILE O 1 232 ? -9.270 24.026 52.668 1.00 127.84 ? 232 ILE O CA 1 +ATOM 28334 C C . ILE O 1 232 ? -10.309 23.898 51.552 1.00 144.08 ? 232 ILE O C 1 +ATOM 28335 O O . ILE O 1 232 ? -11.068 22.926 51.517 1.00 123.00 ? 232 ILE O O 1 +ATOM 28336 C CB . ILE O 1 232 ? -9.689 25.164 53.621 1.00 135.48 ? 232 ILE O CB 1 +ATOM 28337 C CG1 . ILE O 1 232 ? -8.898 25.056 54.928 1.00 149.91 ? 232 ILE O CG1 1 +ATOM 28338 C CG2 . ILE O 1 232 ? -11.197 25.131 53.897 1.00 135.07 ? 232 ILE O CG2 1 +ATOM 28339 C CD1 . ILE O 1 232 ? -8.902 26.323 55.753 1.00 164.69 ? 232 ILE O CD1 1 +ATOM 28340 N N . ASP O 1 233 ? -10.307 24.863 50.630 1.00 170.25 ? 233 ASP O N 1 +ATOM 28341 C CA . ASP O 1 233 ? -11.184 24.834 49.447 1.00 155.74 ? 233 ASP O CA 1 +ATOM 28342 C C . ASP O 1 233 ? -11.024 23.542 48.635 1.00 170.44 ? 233 ASP O C 1 +ATOM 28343 O O . ASP O 1 233 ? -12.002 22.879 48.315 1.00 187.67 ? 233 ASP O O 1 +ATOM 28344 C CB . ASP O 1 233 ? -10.900 26.035 48.529 1.00 131.15 ? 233 ASP O CB 1 +ATOM 28345 C CG . ASP O 1 233 ? -11.209 27.374 49.186 1.00 118.70 ? 233 ASP O CG 1 +ATOM 28346 O OD1 . ASP O 1 233 ? -11.506 27.399 50.402 1.00 119.91 ? 233 ASP O OD1 1 +ATOM 28347 O OD2 . ASP O 1 233 ? -11.205 28.399 48.466 1.00 120.87 ? 233 ASP O OD2 1 +ATOM 28348 N N . ARG O 1 234 ? -9.783 23.170 48.334 1.00 181.68 ? 234 ARG O N 1 +ATOM 28349 C CA . ARG O 1 234 ? -9.511 22.030 47.454 1.00 155.10 ? 234 ARG O CA 1 +ATOM 28350 C C . ARG O 1 234 ? -9.586 20.664 48.146 1.00 138.39 ? 234 ARG O C 1 +ATOM 28351 O O . ARG O 1 234 ? -9.371 19.631 47.509 1.00 154.63 ? 234 ARG O O 1 +ATOM 28352 C CB . ARG O 1 234 ? -8.148 22.216 46.790 1.00 166.77 ? 234 ARG O CB 1 +ATOM 28353 C CG . ARG O 1 234 ? -8.185 23.293 45.730 1.00 134.23 ? 234 ARG O CG 1 +ATOM 28354 C CD . ARG O 1 234 ? -6.818 23.860 45.424 1.00 137.16 ? 234 ARG O CD 1 +ATOM 28355 N NE . ARG O 1 234 ? -7.007 24.908 44.422 1.00 128.98 ? 234 ARG O NE 1 +ATOM 28356 C CZ . ARG O 1 234 ? -6.453 24.915 43.212 1.00 108.54 ? 234 ARG O CZ 1 +ATOM 28357 N NH1 . ARG O 1 234 ? -5.575 23.981 42.897 1.00 126.14 ? 234 ARG O NH1 1 +ATOM 28358 N NH2 . ARG O 1 234 ? -6.719 25.892 42.363 1.00 80.95 ? 234 ARG O NH2 1 +ATOM 28359 N N . GLY O 1 235 ? -9.846 20.656 49.452 1.00 119.17 ? 235 GLY O N 1 +ATOM 28360 C CA . GLY O 1 235 ? -10.007 19.411 50.197 1.00 120.56 ? 235 GLY O CA 1 +ATOM 28361 C C . GLY O 1 235 ? -8.703 18.703 50.513 1.00 124.93 ? 235 GLY O C 1 +ATOM 28362 O O . GLY O 1 235 ? -8.658 17.466 50.554 1.00 130.05 ? 235 GLY O O 1 +ATOM 28363 N N . LEU O 1 236 ? -7.624 19.465 50.695 1.00 119.18 ? 236 LEU O N 1 +ATOM 28364 C CA . LEU O 1 236 ? -6.380 18.882 51.209 1.00 130.27 ? 236 LEU O CA 1 +ATOM 28365 C C . LEU O 1 236 ? -6.571 18.571 52.691 1.00 131.44 ? 236 LEU O C 1 +ATOM 28366 O O . LEU O 1 236 ? -6.230 17.485 53.160 1.00 105.37 ? 236 LEU O O 1 +ATOM 28367 C CB . LEU O 1 236 ? -5.174 19.821 51.009 1.00 144.44 ? 236 LEU O CB 1 +ATOM 28368 C CG . LEU O 1 236 ? -4.456 19.808 49.646 1.00 141.61 ? 236 LEU O CG 1 +ATOM 28369 C CD1 . LEU O 1 236 ? -5.237 20.603 48.616 1.00 104.80 ? 236 LEU O CD1 1 +ATOM 28370 C CD2 . LEU O 1 236 ? -3.045 20.378 49.788 1.00 167.23 ? 236 LEU O CD2 1 +ATOM 28371 N N . TRP O 1 237 ? -7.087 19.549 53.429 1.00 148.63 ? 237 TRP O N 1 +ATOM 28372 C CA . TRP O 1 237 ? -7.268 19.417 54.878 1.00 160.42 ? 237 TRP O CA 1 +ATOM 28373 C C . TRP O 1 237 ? -8.600 20.034 55.296 1.00 168.04 ? 237 TRP O C 1 +ATOM 28374 O O . TRP O 1 237 ? -9.214 20.786 54.522 1.00 182.93 ? 237 TRP O O 1 +ATOM 28375 C CB . TRP O 1 237 ? -6.098 20.064 55.628 1.00 148.69 ? 237 TRP O CB 1 +ATOM 28376 C CG . TRP O 1 237 ? -5.536 21.259 54.912 1.00 164.86 ? 237 TRP O CG 1 +ATOM 28377 C CD1 . TRP O 1 237 ? -6.167 22.448 54.691 1.00 177.34 ? 237 TRP O CD1 1 +ATOM 28378 C CD2 . TRP O 1 237 ? -4.241 21.375 54.304 1.00 147.42 ? 237 TRP O CD2 1 +ATOM 28379 N NE1 . TRP O 1 237 ? -5.348 23.298 53.987 1.00 148.97 ? 237 TRP O NE1 1 +ATOM 28380 C CE2 . TRP O 1 237 ? -4.156 22.669 53.746 1.00 133.56 ? 237 TRP O CE2 1 +ATOM 28381 C CE3 . TRP O 1 237 ? -3.143 20.521 54.196 1.00 139.75 ? 237 TRP O CE3 1 +ATOM 28382 C CZ2 . TRP O 1 237 ? -3.027 23.121 53.079 1.00 116.58 ? 237 TRP O CZ2 1 +ATOM 28383 C CZ3 . TRP O 1 237 ? -2.018 20.980 53.532 1.00 142.76 ? 237 TRP O CZ3 1 +ATOM 28384 C CH2 . TRP O 1 237 ? -1.967 22.276 52.994 1.00 127.73 ? 237 TRP O CH2 1 +ATOM 28385 N N . ASP O 1 238 ? -9.042 19.714 56.512 1.00 171.28 ? 238 ASP O N 1 +ATOM 28386 C CA . ASP O 1 238 ? -10.376 20.108 56.979 1.00 204.81 ? 238 ASP O CA 1 +ATOM 28387 C C . ASP O 1 238 ? -10.367 20.801 58.344 1.00 209.75 ? 238 ASP O C 1 +ATOM 28388 O O . ASP O 1 238 ? -9.540 20.487 59.212 1.00 159.60 ? 238 ASP O O 1 +ATOM 28389 C CB . ASP O 1 238 ? -11.306 18.896 57.043 1.00 190.89 ? 238 ASP O CB 1 +ATOM 28390 C CG . ASP O 1 238 ? -11.413 18.174 55.718 1.00 160.78 ? 238 ASP O CG 1 +ATOM 28391 O OD1 . ASP O 1 238 ? -10.487 17.398 55.405 1.00 138.18 ? 238 ASP O OD1 1 +ATOM 28392 O OD2 . ASP O 1 238 ? -12.412 18.383 54.991 1.00 151.80 ? 238 ASP O OD2 1 +ATOM 28393 N N . LEU O 1 239 ? -11.325 21.714 58.533 1.00 185.16 ? 239 LEU O N 1 +ATOM 28394 C CA . LEU O 1 239 ? -11.445 22.474 59.770 1.00 151.38 ? 239 LEU O CA 1 +ATOM 28395 C C . LEU O 1 239 ? -12.059 21.615 60.859 1.00 137.87 ? 239 LEU O C 1 +ATOM 28396 O O . LEU O 1 239 ? -12.924 20.778 60.597 1.00 139.44 ? 239 LEU O O 1 +ATOM 28397 C CB . LEU O 1 239 ? -12.308 23.721 59.560 1.00 151.37 ? 239 LEU O CB 1 +ATOM 28398 C CG . LEU O 1 239 ? -11.713 24.933 58.848 1.00 182.72 ? 239 LEU O CG 1 +ATOM 28399 C CD1 . LEU O 1 239 ? -12.697 26.096 58.850 1.00 205.68 ? 239 LEU O CD1 1 +ATOM 28400 C CD2 . LEU O 1 239 ? -10.415 25.361 59.505 1.00 202.40 ? 239 LEU O CD2 1 +ATOM 28401 N N . GLN O 1 240 ? -11.600 21.825 62.088 1.00 137.61 ? 240 GLN O N 1 +ATOM 28402 C CA . GLN O 1 240 ? -12.242 21.232 63.263 1.00 119.32 ? 240 GLN O CA 1 +ATOM 28403 C C . GLN O 1 240 ? -13.730 21.581 63.299 1.00 137.77 ? 240 GLN O C 1 +ATOM 28404 O O . GLN O 1 240 ? -14.587 20.701 63.320 1.00 125.38 ? 240 GLN O O 1 +ATOM 28405 C CB . GLN O 1 240 ? -11.560 21.730 64.542 1.00 108.73 ? 240 GLN O CB 1 +ATOM 28406 C CG . GLN O 1 240 ? -12.028 21.015 65.802 1.00 106.99 ? 240 GLN O CG 1 +ATOM 28407 C CD . GLN O 1 240 ? -11.649 19.550 65.803 1.00 103.74 ? 240 GLN O CD 1 +ATOM 28408 O OE1 . GLN O 1 240 ? -10.504 19.192 66.114 1.00 130.48 ? 240 GLN O OE1 1 +ATOM 28409 N NE2 . GLN O 1 240 ? -12.585 18.695 65.412 1.00 102.72 ? 240 GLN O NE2 1 +ATOM 28410 N N . ASN O 1 241 ? -14.012 22.880 63.263 1.00 165.11 ? 241 ASN O N 1 +ATOM 28411 C CA . ASN O 1 241 ? -15.377 23.396 63.258 1.00 153.85 ? 241 ASN O CA 1 +ATOM 28412 C C . ASN O 1 241 ? -15.773 23.894 61.884 1.00 166.71 ? 241 ASN O C 1 +ATOM 28413 O O . ASN O 1 241 ? -15.268 24.929 61.413 1.00 185.81 ? 241 ASN O O 1 +ATOM 28414 C CB . ASN O 1 241 ? -15.496 24.550 64.243 1.00 153.09 ? 241 ASN O CB 1 +ATOM 28415 C CG . ASN O 1 241 ? -16.126 24.128 65.541 1.00 162.36 ? 241 ASN O CG 1 +ATOM 28416 O OD1 . ASN O 1 241 ? -17.298 24.404 65.778 1.00 185.33 ? 241 ASN O OD1 1 +ATOM 28417 N ND2 . ASN O 1 241 ? -15.356 23.452 66.394 1.00 169.79 ? 241 ASN O ND2 1 +ATOM 28418 N N . LYS O 1 242 ? -16.692 23.174 61.252 1.00 149.60 ? 242 LYS O N 1 +ATOM 28419 C CA . LYS O 1 242 ? -17.140 23.537 59.915 1.00 168.89 ? 242 LYS O CA 1 +ATOM 28420 C C . LYS O 1 242 ? -17.878 24.869 59.976 1.00 165.56 ? 242 LYS O C 1 +ATOM 28421 O O . LYS O 1 242 ? -17.915 25.623 58.988 1.00 145.67 ? 242 LYS O O 1 +ATOM 28422 C CB . LYS O 1 242 ? -18.026 22.431 59.325 1.00 166.76 ? 242 LYS O CB 1 +ATOM 28423 C CG . LYS O 1 242 ? -17.417 21.034 59.423 1.00 163.25 ? 242 LYS O CG 1 +ATOM 28424 C CD . LYS O 1 242 ? -17.352 20.334 58.071 1.00 163.79 ? 242 LYS O CD 1 +ATOM 28425 C CE . LYS O 1 242 ? -15.987 19.697 57.845 1.00 155.16 ? 242 LYS O CE 1 +ATOM 28426 N NZ . LYS O 1 242 ? -15.939 18.875 56.609 1.00 150.41 ? 242 LYS O NZ 1 +ATOM 28427 N N . ALA O 1 243 ? -18.423 25.151 61.163 1.00 169.58 ? 243 ALA O N 1 +ATOM 28428 C CA . ALA O 1 243 ? -19.067 26.425 61.473 1.00 190.19 ? 243 ALA O CA 1 +ATOM 28429 C C . ALA O 1 243 ? -18.085 27.588 61.372 1.00 214.85 ? 243 ALA O C 1 +ATOM 28430 O O . ALA O 1 243 ? -18.508 28.746 61.258 1.00 266.09 ? 243 ALA O O 1 +ATOM 28431 C CB . ALA O 1 243 ? -19.680 26.382 62.870 1.00 156.19 ? 243 ALA O CB 1 +ATOM 28432 N N . GLU O 1 244 ? -16.786 27.291 61.427 1.00 193.35 ? 244 GLU O N 1 +ATOM 28433 C CA . GLU O 1 244 ? -15.783 28.348 61.401 1.00 171.80 ? 244 GLU O CA 1 +ATOM 28434 C C . GLU O 1 244 ? -15.292 28.638 59.997 1.00 145.69 ? 244 GLU O C 1 +ATOM 28435 O O . GLU O 1 244 ? -14.308 29.351 59.837 1.00 155.06 ? 244 GLU O O 1 +ATOM 28436 C CB . GLU O 1 244 ? -14.602 28.002 62.311 1.00 172.80 ? 244 GLU O CB 1 +ATOM 28437 C CG . GLU O 1 244 ? -14.910 28.115 63.796 1.00 176.85 ? 244 GLU O CG 1 +ATOM 28438 C CD . GLU O 1 244 ? -13.662 28.026 64.661 1.00 166.55 ? 244 GLU O CD 1 +ATOM 28439 O OE1 . GLU O 1 244 ? -13.149 26.902 64.860 1.00 146.43 ? 244 GLU O OE1 1 +ATOM 28440 O OE2 . GLU O 1 244 ? -13.213 29.082 65.164 1.00 150.20 ? 244 GLU O OE2 1 +ATOM 28441 N N . ARG O 1 245 ? -15.965 28.095 58.985 1.00 135.60 ? 245 ARG O N 1 +ATOM 28442 C CA . ARG O 1 245 ? -15.630 28.421 57.595 1.00 175.05 ? 245 ARG O CA 1 +ATOM 28443 C C . ARG O 1 245 ? -15.700 29.917 57.299 1.00 178.81 ? 245 ARG O C 1 +ATOM 28444 O O . ARG O 1 245 ? -14.905 30.436 56.511 1.00 143.50 ? 245 ARG O O 1 +ATOM 28445 C CB . ARG O 1 245 ? -16.524 27.689 56.606 1.00 188.06 ? 245 ARG O CB 1 +ATOM 28446 C CG . ARG O 1 245 ? -16.085 27.858 55.146 1.00 194.11 ? 245 ARG O CG 1 +ATOM 28447 C CD . ARG O 1 245 ? -16.934 27.031 54.163 1.00 195.65 ? 245 ARG O CD 1 +ATOM 28448 N NE . ARG O 1 245 ? -16.282 25.769 53.802 1.00 191.22 ? 245 ARG O NE 1 +ATOM 28449 C CZ . ARG O 1 245 ? -15.205 25.668 53.021 1.00 189.37 ? 245 ARG O CZ 1 +ATOM 28450 N NH1 . ARG O 1 245 ? -14.626 26.748 52.528 1.00 173.02 ? 245 ARG O NH1 1 +ATOM 28451 N NH2 . ARG O 1 245 ? -14.682 24.479 52.749 1.00 196.22 ? 245 ARG O NH2 1 +ATOM 28452 N N . GLN O 1 246 ? -16.664 30.604 57.907 1.00 194.57 ? 246 GLN O N 1 +ATOM 28453 C CA . GLN O 1 246 ? -16.865 32.028 57.631 1.00 194.12 ? 246 GLN O CA 1 +ATOM 28454 C C . GLN O 1 246 ? -16.108 32.913 58.613 1.00 174.14 ? 246 GLN O C 1 +ATOM 28455 O O . GLN O 1 246 ? -16.455 34.073 58.814 1.00 184.35 ? 246 GLN O O 1 +ATOM 28456 C CB . GLN O 1 246 ? -18.358 32.363 57.632 1.00 198.26 ? 246 GLN O CB 1 +ATOM 28457 C CG . GLN O 1 246 ? -19.117 31.662 56.509 1.00 183.32 ? 246 GLN O CG 1 +ATOM 28458 C CD . GLN O 1 246 ? -18.889 32.257 55.125 1.00 186.65 ? 246 GLN O CD 1 +ATOM 28459 O OE1 . GLN O 1 246 ? -17.755 32.500 54.714 1.00 200.15 ? 246 GLN O OE1 1 +ATOM 28460 N NE2 . GLN O 1 246 ? -19.972 32.443 54.378 1.00 204.75 ? 246 GLN O NE2 1 +ATOM 28461 N N . ASN O 1 247 ? -15.090 32.339 59.246 1.00 162.61 ? 247 ASN O N 1 +ATOM 28462 C CA . ASN O 1 247 ? -14.116 33.096 60.030 1.00 163.23 ? 247 ASN O CA 1 +ATOM 28463 C C . ASN O 1 247 ? -13.719 34.404 59.342 1.00 167.44 ? 247 ASN O C 1 +ATOM 28464 O O . ASN O 1 247 ? -13.497 34.423 58.125 1.00 185.68 ? 247 ASN O O 1 +ATOM 28465 C CB . ASN O 1 247 ? -12.863 32.241 60.232 1.00 179.60 ? 247 ASN O CB 1 +ATOM 28466 C CG . ASN O 1 247 ? -12.093 32.624 61.466 1.00 160.06 ? 247 ASN O CG 1 +ATOM 28467 O OD1 . ASN O 1 247 ? -10.993 33.181 61.385 1.00 159.51 ? 247 ASN O OD1 1 +ATOM 28468 N ND2 . ASN O 1 247 ? -12.649 32.292 62.621 1.00 150.78 ? 247 ASN O ND2 1 +ATOM 28469 N N . ASP O 1 248 ? -13.600 35.478 60.123 1.00 165.24 ? 248 ASP O N 1 +ATOM 28470 C CA . ASP O 1 248 ? -13.282 36.812 59.579 1.00 194.99 ? 248 ASP O CA 1 +ATOM 28471 C C . ASP O 1 248 ? -12.025 36.782 58.704 1.00 221.88 ? 248 ASP O C 1 +ATOM 28472 O O . ASP O 1 248 ? -11.986 37.352 57.601 1.00 230.60 ? 248 ASP O O 1 +ATOM 28473 C CB . ASP O 1 248 ? -13.055 37.820 60.715 1.00 191.46 ? 248 ASP O CB 1 +ATOM 28474 C CG . ASP O 1 248 ? -14.332 38.190 61.443 1.00 196.42 ? 248 ASP O CG 1 +ATOM 28475 O OD1 . ASP O 1 248 ? -15.388 38.332 60.785 1.00 206.78 ? 248 ASP O OD1 1 +ATOM 28476 O OD2 . ASP O 1 248 ? -14.271 38.368 62.678 1.00 185.64 ? 248 ASP O OD2 1 +ATOM 28477 N N . ILE O 1 249 ? -10.989 36.133 59.225 1.00 214.36 ? 249 ILE O N 1 +ATOM 28478 C CA . ILE O 1 249 ? -9.696 36.077 58.561 1.00 191.65 ? 249 ILE O CA 1 +ATOM 28479 C C . ILE O 1 249 ? -9.808 35.275 57.260 1.00 176.35 ? 249 ILE O C 1 +ATOM 28480 O O . ILE O 1 249 ? -9.395 35.732 56.187 1.00 162.95 ? 249 ILE O O 1 +ATOM 28481 C CB . ILE O 1 249 ? -8.638 35.446 59.492 1.00 184.05 ? 249 ILE O CB 1 +ATOM 28482 C CG1 . ILE O 1 249 ? -8.442 36.313 60.743 1.00 163.84 ? 249 ILE O CG1 1 +ATOM 28483 C CG2 . ILE O 1 249 ? -7.313 35.300 58.761 1.00 209.90 ? 249 ILE O CG2 1 +ATOM 28484 C CD1 . ILE O 1 249 ? -7.819 35.581 61.913 1.00 148.92 ? 249 ILE O CD1 1 +ATOM 28485 N N . LEU O 1 250 ? -10.406 34.092 57.359 1.00 156.40 ? 250 LEU O N 1 +ATOM 28486 C CA . LEU O 1 250 ? -10.550 33.205 56.204 1.00 154.83 ? 250 LEU O CA 1 +ATOM 28487 C C . LEU O 1 250 ? -11.337 33.843 55.060 1.00 158.40 ? 250 LEU O C 1 +ATOM 28488 O O . LEU O 1 250 ? -11.013 33.627 53.890 1.00 178.22 ? 250 LEU O O 1 +ATOM 28489 C CB . LEU O 1 250 ? -11.209 31.886 56.619 1.00 151.37 ? 250 LEU O CB 1 +ATOM 28490 C CG . LEU O 1 250 ? -10.276 30.874 57.290 1.00 145.81 ? 250 LEU O CG 1 +ATOM 28491 C CD1 . LEU O 1 250 ? -11.042 29.729 57.930 1.00 136.84 ? 250 LEU O CD1 1 +ATOM 28492 C CD2 . LEU O 1 250 ? -9.283 30.330 56.281 1.00 165.83 ? 250 LEU O CD2 1 +ATOM 28493 N N . VAL O 1 251 ? -12.384 34.596 55.398 1.00 155.42 ? 251 VAL O N 1 +ATOM 28494 C CA . VAL O 1 251 ? -13.197 35.265 54.378 1.00 166.37 ? 251 VAL O CA 1 +ATOM 28495 C C . VAL O 1 251 ? -12.496 36.507 53.833 1.00 169.13 ? 251 VAL O C 1 +ATOM 28496 O O . VAL O 1 251 ? -12.755 36.930 52.702 1.00 189.81 ? 251 VAL O O 1 +ATOM 28497 C CB . VAL O 1 251 ? -14.601 35.652 54.898 1.00 177.22 ? 251 VAL O CB 1 +ATOM 28498 C CG1 . VAL O 1 251 ? -15.321 34.427 55.452 1.00 172.67 ? 251 VAL O CG1 1 +ATOM 28499 C CG2 . VAL O 1 251 ? -14.522 36.766 55.934 1.00 188.65 ? 251 VAL O CG2 1 +ATOM 28500 N N . LYS O 1 252 ? -11.602 37.082 54.634 1.00 159.81 ? 252 LYS O N 1 +ATOM 28501 C CA . LYS O 1 252 ? -10.791 38.213 54.188 1.00 163.99 ? 252 LYS O CA 1 +ATOM 28502 C C . LYS O 1 252 ? -9.812 37.782 53.079 1.00 164.60 ? 252 LYS O C 1 +ATOM 28503 O O . LYS O 1 252 ? -9.719 38.424 52.025 1.00 113.06 ? 252 LYS O O 1 +ATOM 28504 C CB . LYS O 1 252 ? -10.051 38.802 55.388 1.00 155.13 ? 252 LYS O CB 1 +ATOM 28505 C CG . LYS O 1 252 ? -9.138 39.977 55.077 1.00 161.98 ? 252 LYS O CG 1 +ATOM 28506 C CD . LYS O 1 252 ? -8.440 40.452 56.350 1.00 169.32 ? 252 LYS O CD 1 +ATOM 28507 C CE . LYS O 1 252 ? -6.946 40.659 56.139 1.00 164.06 ? 252 LYS O CE 1 +ATOM 28508 N NZ . LYS O 1 252 ? -6.206 40.863 57.416 1.00 140.84 ? 252 LYS O NZ 1 +ATOM 28509 N N . TYR O 1 253 ? -9.140 36.655 53.296 1.00 180.50 ? 253 TYR O N 1 +ATOM 28510 C CA . TYR O 1 253 ? -8.175 36.129 52.322 1.00 185.97 ? 253 TYR O CA 1 +ATOM 28511 C C . TYR O 1 253 ? -8.879 35.457 51.153 1.00 178.06 ? 253 TYR O C 1 +ATOM 28512 O O . TYR O 1 253 ? -8.379 35.463 50.027 1.00 185.32 ? 253 TYR O O 1 +ATOM 28513 C CB . TYR O 1 253 ? -7.186 35.168 53.001 1.00 190.73 ? 253 TYR O CB 1 +ATOM 28514 C CG . TYR O 1 253 ? -6.207 35.909 53.901 1.00 185.02 ? 253 TYR O CG 1 +ATOM 28515 C CD1 . TYR O 1 253 ? -5.063 36.502 53.377 1.00 161.73 ? 253 TYR O CD1 1 +ATOM 28516 C CD2 . TYR O 1 253 ? -6.464 36.079 55.262 1.00 188.68 ? 253 TYR O CD2 1 +ATOM 28517 C CE1 . TYR O 1 253 ? -4.193 37.210 54.193 1.00 147.80 ? 253 TYR O CE1 1 +ATOM 28518 C CE2 . TYR O 1 253 ? -5.581 36.769 56.085 1.00 159.72 ? 253 TYR O CE2 1 +ATOM 28519 C CZ . TYR O 1 253 ? -4.450 37.336 55.541 1.00 141.89 ? 253 TYR O CZ 1 +ATOM 28520 O OH . TYR O 1 253 ? -3.583 38.047 56.340 1.00 131.04 ? 253 TYR O OH 1 +ATOM 28521 N N . ARG O 1 254 ? -10.036 34.864 51.435 1.00 168.35 ? 254 ARG O N 1 +ATOM 28522 C CA . ARG O 1 254 ? -10.915 34.353 50.382 1.00 156.60 ? 254 ARG O CA 1 +ATOM 28523 C C . ARG O 1 254 ? -11.302 35.486 49.438 1.00 156.90 ? 254 ARG O C 1 +ATOM 28524 O O . ARG O 1 254 ? -11.353 35.297 48.219 1.00 171.81 ? 254 ARG O O 1 +ATOM 28525 C CB . ARG O 1 254 ? -12.183 33.725 50.983 1.00 151.05 ? 254 ARG O CB 1 +ATOM 28526 C CG . ARG O 1 254 ? -13.092 33.075 49.949 1.00 130.95 ? 254 ARG O CG 1 +ATOM 28527 C CD . ARG O 1 254 ? -14.103 32.123 50.566 1.00 135.29 ? 254 ARG O CD 1 +ATOM 28528 N NE . ARG O 1 254 ? -13.506 30.940 51.186 1.00 149.24 ? 254 ARG O NE 1 +ATOM 28529 C CZ . ARG O 1 254 ? -13.425 30.711 52.497 1.00 159.94 ? 254 ARG O CZ 1 +ATOM 28530 N NH1 . ARG O 1 254 ? -13.902 31.581 53.374 1.00 152.02 ? 254 ARG O NH1 1 +ATOM 28531 N NH2 . ARG O 1 254 ? -12.864 29.588 52.936 1.00 164.04 ? 254 ARG O NH2 1 +ATOM 28532 N N . HIS O 1 255 ? -11.563 36.660 50.015 1.00 168.79 ? 255 HIS O N 1 +ATOM 28533 C CA . HIS O 1 255 ? -11.953 37.843 49.243 1.00 186.24 ? 255 HIS O CA 1 +ATOM 28534 C C . HIS O 1 255 ? -10.818 38.395 48.391 1.00 176.70 ? 255 HIS O C 1 +ATOM 28535 O O . HIS O 1 255 ? -11.049 38.885 47.285 1.00 134.75 ? 255 HIS O O 1 +ATOM 28536 C CB . HIS O 1 255 ? -12.501 38.942 50.163 1.00 207.53 ? 255 HIS O CB 1 +ATOM 28537 C CG . HIS O 1 255 ? -13.988 39.104 50.086 1.00 205.21 ? 255 HIS O CG 1 +ATOM 28538 N ND1 . HIS O 1 255 ? -14.865 38.210 50.663 1.00 193.69 ? 255 HIS O ND1 1 +ATOM 28539 C CD2 . HIS O 1 255 ? -14.752 40.042 49.476 1.00 193.85 ? 255 HIS O CD2 1 +ATOM 28540 C CE1 . HIS O 1 255 ? -16.106 38.600 50.424 1.00 189.13 ? 255 HIS O CE1 1 +ATOM 28541 N NE2 . HIS O 1 255 ? -16.065 39.709 49.708 1.00 184.89 ? 255 HIS O NE2 1 +ATOM 28542 N N . MET O 1 256 ? -9.589 38.293 48.888 1.00 175.66 ? 256 MET O N 1 +ATOM 28543 C CA . MET O 1 256 ? -8.439 38.766 48.114 1.00 185.36 ? 256 MET O CA 1 +ATOM 28544 C C . MET O 1 256 ? -8.182 37.901 46.861 1.00 214.80 ? 256 MET O C 1 +ATOM 28545 O O . MET O 1 256 ? -7.616 38.386 45.874 1.00 205.64 ? 256 MET O O 1 +ATOM 28546 C CB . MET O 1 256 ? -7.193 38.851 49.003 1.00 172.42 ? 256 MET O CB 1 +ATOM 28547 C CG . MET O 1 256 ? -7.412 39.660 50.278 1.00 160.93 ? 256 MET O CG 1 +ATOM 28548 S SD . MET O 1 256 ? -5.930 40.252 51.093 1.00 140.93 ? 256 MET O SD 1 +ATOM 28549 C CE . MET O 1 256 ? -5.357 41.466 49.899 1.00 107.65 ? 256 MET O CE 1 +ATOM 28550 N N . SER O 1 257 ? -8.643 36.647 46.891 1.00 219.09 ? 257 SER O N 1 +ATOM 28551 C CA . SER O 1 257 ? -8.562 35.738 45.736 1.00 189.36 ? 257 SER O CA 1 +ATOM 28552 C C . SER O 1 257 ? -9.603 36.073 44.670 1.00 163.84 ? 257 SER O C 1 +ATOM 28553 O O . SER O 1 257 ? -9.347 36.855 43.760 1.00 120.25 ? 257 SER O O 1 +ATOM 28554 C CB . SER O 1 257 ? -8.760 34.283 46.185 1.00 179.29 ? 257 SER O CB 1 +ATOM 28555 O OG . SER O 1 257 ? -8.029 34.015 47.363 1.00 200.26 ? 257 SER O OG 1 +ATOM 28556 N N . LEU P 1 2 ? 10.522 55.021 70.032 1.00 128.16 ? 2 LEU P N 1 +ATOM 28557 C CA . LEU P 1 2 ? 10.692 55.019 68.548 1.00 145.72 ? 2 LEU P CA 1 +ATOM 28558 C C . LEU P 1 2 ? 12.198 55.062 68.193 1.00 163.64 ? 2 LEU P C 1 +ATOM 28559 O O . LEU P 1 2 ? 12.727 56.064 67.657 1.00 136.21 ? 2 LEU P O 1 +ATOM 28560 C CB . LEU P 1 2 ? 9.918 56.179 67.896 1.00 153.85 ? 2 LEU P CB 1 +ATOM 28561 C CG . LEU P 1 2 ? 8.380 56.243 68.046 1.00 128.34 ? 2 LEU P CG 1 +ATOM 28562 C CD1 . LEU P 1 2 ? 7.850 57.491 67.340 1.00 94.38 ? 2 LEU P CD1 1 +ATOM 28563 C CD2 . LEU P 1 2 ? 7.641 54.996 67.548 1.00 122.14 ? 2 LEU P CD2 1 +ATOM 28564 N N . THR P 1 3 ? 12.874 53.983 68.589 1.00 177.50 ? 3 THR P N 1 +ATOM 28565 C CA . THR P 1 3 ? 14.183 53.590 68.065 1.00 183.18 ? 3 THR P CA 1 +ATOM 28566 C C . THR P 1 3 ? 14.259 52.053 67.874 1.00 207.16 ? 3 THR P C 1 +ATOM 28567 O O . THR P 1 3 ? 15.270 51.504 67.421 1.00 172.03 ? 3 THR P O 1 +ATOM 28568 C CB . THR P 1 3 ? 15.322 54.022 69.005 1.00 157.66 ? 3 THR P CB 1 +ATOM 28569 O OG1 . THR P 1 3 ? 15.259 53.256 70.224 1.00 126.07 ? 3 THR P OG1 1 +ATOM 28570 C CG2 . THR P 1 3 ? 15.266 55.535 69.282 1.00 128.33 ? 3 THR P CG2 1 +ATOM 28571 N N . ALA P 1 4 ? 13.202 51.356 68.272 1.00 211.62 ? 4 ALA P N 1 +ATOM 28572 C CA . ALA P 1 4 ? 12.927 50.007 67.763 1.00 168.95 ? 4 ALA P CA 1 +ATOM 28573 C C . ALA P 1 4 ? 12.390 50.130 66.307 1.00 127.75 ? 4 ALA P C 1 +ATOM 28574 O O . ALA P 1 4 ? 12.400 51.217 65.748 1.00 95.81 ? 4 ALA P O 1 +ATOM 28575 C CB . ALA P 1 4 ? 11.953 49.298 68.708 1.00 154.82 ? 4 ALA P CB 1 +ATOM 28576 N N . PRO P 1 5 ? 11.922 49.034 65.683 1.00 101.25 ? 5 PRO P N 1 +ATOM 28577 C CA . PRO P 1 5 ? 11.687 49.242 64.265 1.00 93.35 ? 5 PRO P CA 1 +ATOM 28578 C C . PRO P 1 5 ? 10.367 49.925 63.966 1.00 101.28 ? 5 PRO P C 1 +ATOM 28579 O O . PRO P 1 5 ? 9.544 50.115 64.862 1.00 151.76 ? 5 PRO P O 1 +ATOM 28580 C CB . PRO P 1 5 ? 11.668 47.821 63.718 1.00 125.65 ? 5 PRO P CB 1 +ATOM 28581 C CG . PRO P 1 5 ? 11.220 46.946 64.858 1.00 122.29 ? 5 PRO P CG 1 +ATOM 28582 C CD . PRO P 1 5 ? 11.480 47.695 66.136 1.00 113.01 ? 5 PRO P CD 1 +ATOM 28583 N N . PRO P 1 6 ? 10.172 50.354 62.720 1.00 135.99 ? 6 PRO P N 1 +ATOM 28584 C CA . PRO P 1 6 ? 8.849 50.814 62.256 1.00 167.57 ? 6 PRO P CA 1 +ATOM 28585 C C . PRO P 1 6 ? 7.924 49.655 61.894 1.00 177.53 ? 6 PRO P C 1 +ATOM 28586 O O . PRO P 1 6 ? 8.400 48.581 61.535 1.00 203.76 ? 6 PRO P O 1 +ATOM 28587 C CB . PRO P 1 6 ? 9.165 51.657 61.015 1.00 175.14 ? 6 PRO P CB 1 +ATOM 28588 C CG . PRO P 1 6 ? 10.549 51.299 60.607 1.00 179.84 ? 6 PRO P CG 1 +ATOM 28589 C CD . PRO P 1 6 ? 11.251 50.630 61.759 1.00 157.03 ? 6 PRO P CD 1 +ATOM 28590 N N . LYS P 1 7 ? 6.613 49.866 62.001 1.00 172.87 ? 7 LYS P N 1 +ATOM 28591 C CA . LYS P 1 7 ? 5.637 48.802 61.723 1.00 167.80 ? 7 LYS P CA 1 +ATOM 28592 C C . LYS P 1 7 ? 5.111 48.893 60.296 1.00 168.03 ? 7 LYS P C 1 +ATOM 28593 O O . LYS P 1 7 ? 5.356 49.875 59.593 1.00 135.98 ? 7 LYS P O 1 +ATOM 28594 C CB . LYS P 1 7 ? 4.474 48.823 62.724 1.00 142.55 ? 7 LYS P CB 1 +ATOM 28595 C CG . LYS P 1 7 ? 4.850 48.404 64.125 1.00 145.23 ? 7 LYS P CG 1 +ATOM 28596 C CD . LYS P 1 7 ? 4.969 49.576 65.093 1.00 140.92 ? 7 LYS P CD 1 +ATOM 28597 C CE . LYS P 1 7 ? 5.042 49.070 66.525 1.00 161.88 ? 7 LYS P CE 1 +ATOM 28598 N NZ . LYS P 1 7 ? 5.807 49.992 67.407 1.00 189.29 ? 7 LYS P NZ 1 +ATOM 28599 N N . GLU P 1 8 ? 4.408 47.846 59.872 1.00 181.39 ? 8 GLU P N 1 +ATOM 28600 C CA . GLU P 1 8 ? 4.133 47.613 58.458 1.00 180.68 ? 8 GLU P CA 1 +ATOM 28601 C C . GLU P 1 8 ? 3.225 48.662 57.804 1.00 139.65 ? 8 GLU P C 1 +ATOM 28602 O O . GLU P 1 8 ? 2.085 48.869 58.201 1.00 153.18 ? 8 GLU P O 1 +ATOM 28603 C CB . GLU P 1 8 ? 3.624 46.199 58.239 1.00 198.76 ? 8 GLU P CB 1 +ATOM 28604 C CG . GLU P 1 8 ? 4.724 45.311 57.598 1.00 245.21 ? 8 GLU P CG 1 +ATOM 28605 C CD . GLU P 1 8 ? 5.342 44.297 58.559 1.00 276.07 ? 8 GLU P CD 1 +ATOM 28606 O OE1 . GLU P 1 8 ? 5.611 44.704 59.717 1.00 304.42 ? 8 GLU P OE1 1 +ATOM 28607 O OE2 . GLU P 1 8 ? 5.633 43.126 58.139 1.00 303.39 ? 8 GLU P OE2 1 +ATOM 28608 N N . ALA P 1 9 ? 3.782 49.374 56.832 1.00 128.50 ? 9 ALA P N 1 +ATOM 28609 C CA . ALA P 1 9 ? 3.037 50.329 56.016 1.00 117.73 ? 9 ALA P CA 1 +ATOM 28610 C C . ALA P 1 9 ? 2.602 49.658 54.717 1.00 111.74 ? 9 ALA P C 1 +ATOM 28611 O O . ALA P 1 9 ? 3.438 49.326 53.869 1.00 151.91 ? 9 ALA P O 1 +ATOM 28612 C CB . ALA P 1 9 ? 3.908 51.543 55.717 1.00 102.49 ? 9 ALA P CB 1 +ATOM 28613 N N . ALA P 1 10 ? 1.291 49.502 54.556 1.00 94.22 ? 10 ALA P N 1 +ATOM 28614 C CA . ALA P 1 10 ? 0.673 48.715 53.473 1.00 99.10 ? 10 ALA P CA 1 +ATOM 28615 C C . ALA P 1 10 ? 0.626 47.250 53.873 1.00 105.83 ? 10 ALA P C 1 +ATOM 28616 O O . ALA P 1 10 ? 1.401 46.802 54.717 1.00 119.21 ? 10 ALA P O 1 +ATOM 28617 C CB . ALA P 1 10 ? 1.364 48.913 52.114 1.00 80.70 ? 10 ALA P CB 1 +ATOM 28618 N N . ARG P 1 11 ? -0.282 46.505 53.251 1.00 123.64 ? 11 ARG P N 1 +ATOM 28619 C CA . ARG P 1 11 ? -0.448 45.087 53.573 1.00 141.89 ? 11 ARG P CA 1 +ATOM 28620 C C . ARG P 1 11 ? 0.163 44.205 52.470 1.00 145.80 ? 11 ARG P C 1 +ATOM 28621 O O . ARG P 1 11 ? 0.380 44.652 51.327 1.00 156.57 ? 11 ARG P O 1 +ATOM 28622 C CB . ARG P 1 11 ? -1.896 44.738 53.895 1.00 152.43 ? 11 ARG P CB 1 +ATOM 28623 C CG . ARG P 1 11 ? -2.303 45.052 55.329 1.00 161.08 ? 11 ARG P CG 1 +ATOM 28624 C CD . ARG P 1 11 ? -3.769 44.842 55.616 1.00 181.69 ? 11 ARG P CD 1 +ATOM 28625 N NE . ARG P 1 11 ? -4.001 44.729 57.053 1.00 185.84 ? 11 ARG P NE 1 +ATOM 28626 C CZ . ARG P 1 11 ? -5.204 44.607 57.600 1.00 181.30 ? 11 ARG P CZ 1 +ATOM 28627 N NH1 . ARG P 1 11 ? -6.282 44.568 56.830 1.00 175.79 ? 11 ARG P NH1 1 +ATOM 28628 N NH2 . ARG P 1 11 ? -5.329 44.514 58.914 1.00 170.41 ? 11 ARG P NH2 1 +ATOM 28629 N N . PRO P 1 12 ? 0.564 42.981 52.832 1.00 151.87 ? 12 PRO P N 1 +ATOM 28630 C CA . PRO P 1 12 ? 0.928 42.042 51.783 1.00 148.30 ? 12 PRO P CA 1 +ATOM 28631 C C . PRO P 1 12 ? -0.311 41.699 50.981 1.00 142.08 ? 12 PRO P C 1 +ATOM 28632 O O . PRO P 1 12 ? -1.289 41.191 51.538 1.00 157.71 ? 12 PRO P O 1 +ATOM 28633 C CB . PRO P 1 12 ? 1.430 40.815 52.550 1.00 178.19 ? 12 PRO P CB 1 +ATOM 28634 C CG . PRO P 1 12 ? 1.674 41.271 53.950 1.00 187.75 ? 12 PRO P CG 1 +ATOM 28635 C CD . PRO P 1 12 ? 0.716 42.403 54.176 1.00 173.91 ? 12 PRO P CD 1 +ATOM 28636 N N . THR P 1 13 ? -0.321 42.103 49.718 1.00 133.51 ? 13 THR P N 1 +ATOM 28637 C CA . THR P 1 13 ? -1.355 41.671 48.794 1.00 126.01 ? 13 THR P CA 1 +ATOM 28638 C C . THR P 1 13 ? -0.865 40.441 48.051 1.00 132.79 ? 13 THR P C 1 +ATOM 28639 O O . THR P 1 13 ? 0.349 40.209 47.989 1.00 197.18 ? 13 THR P O 1 +ATOM 28640 C CB . THR P 1 13 ? -1.674 42.784 47.788 1.00 113.85 ? 13 THR P CB 1 +ATOM 28641 O OG1 . THR P 1 13 ? -2.823 42.401 47.019 1.00 132.09 ? 13 THR P OG1 1 +ATOM 28642 C CG2 . THR P 1 13 ? -0.462 43.090 46.864 1.00 95.48 ? 13 THR P CG2 1 +ATOM 28643 N N . LEU P 1 14 ? -1.767 39.660 47.464 1.00 100.79 ? 14 LEU P N 1 +ATOM 28644 C CA . LEU P 1 14 ? -1.289 38.656 46.515 1.00 96.63 ? 14 LEU P CA 1 +ATOM 28645 C C . LEU P 1 14 ? -0.898 39.356 45.176 1.00 70.28 ? 14 LEU P C 1 +ATOM 28646 O O . LEU P 1 14 ? -1.189 40.499 44.994 1.00 45.63 ? 14 LEU P O 1 +ATOM 28647 C CB . LEU P 1 14 ? -2.257 37.486 46.329 1.00 87.71 ? 14 LEU P CB 1 +ATOM 28648 C CG . LEU P 1 14 ? -3.671 37.803 45.915 1.00 100.01 ? 14 LEU P CG 1 +ATOM 28649 C CD1 . LEU P 1 14 ? -4.219 36.706 45.018 1.00 89.53 ? 14 LEU P CD1 1 +ATOM 28650 C CD2 . LEU P 1 14 ? -4.502 37.930 47.159 1.00 115.47 ? 14 LEU P CD2 1 +ATOM 28651 N N . MET P 1 15 ? -0.028 38.744 44.385 1.00 83.89 ? 15 MET P N 1 +ATOM 28652 C CA . MET P 1 15 ? 0.888 39.511 43.524 1.00 91.20 ? 15 MET P CA 1 +ATOM 28653 C C . MET P 1 15 ? 0.065 40.130 42.416 1.00 78.61 ? 15 MET P C 1 +ATOM 28654 O O . MET P 1 15 ? -0.598 39.414 41.664 1.00 76.38 ? 15 MET P O 1 +ATOM 28655 C CB . MET P 1 15 ? 2.048 38.625 42.960 1.00 125.94 ? 15 MET P CB 1 +ATOM 28656 C CG . MET P 1 15 ? 3.325 39.404 42.604 1.00 117.08 ? 15 MET P CG 1 +ATOM 28657 S SD . MET P 1 15 ? 4.382 38.878 41.204 1.00 105.19 ? 15 MET P SD 1 +ATOM 28658 C CE . MET P 1 15 ? 3.307 37.931 40.128 1.00 89.37 ? 15 MET P CE 1 +ATOM 28659 N N . PRO P 1 16 ? 0.171 41.451 42.262 1.00 94.11 ? 16 PRO P N 1 +ATOM 28660 C CA . PRO P 1 16 ? -0.623 42.239 41.326 1.00 116.47 ? 16 PRO P CA 1 +ATOM 28661 C C . PRO P 1 16 ? -0.426 41.902 39.841 1.00 116.18 ? 16 PRO P C 1 +ATOM 28662 O O . PRO P 1 16 ? 0.258 42.617 39.107 1.00 89.09 ? 16 PRO P O 1 +ATOM 28663 C CB . PRO P 1 16 ? -0.184 43.678 41.621 1.00 127.34 ? 16 PRO P CB 1 +ATOM 28664 C CG . PRO P 1 16 ? 1.181 43.543 42.177 1.00 123.12 ? 16 PRO P CG 1 +ATOM 28665 C CD . PRO P 1 16 ? 1.150 42.280 42.980 1.00 101.40 ? 16 PRO P CD 1 +ATOM 28666 N N . ARG P 1 17 ? -1.106 40.854 39.398 1.00 121.54 ? 17 ARG P N 1 +ATOM 28667 C CA . ARG P 1 17 ? -1.165 40.518 37.982 1.00 124.33 ? 17 ARG P CA 1 +ATOM 28668 C C . ARG P 1 17 ? -2.339 41.255 37.333 1.00 94.38 ? 17 ARG P C 1 +ATOM 28669 O O . ARG P 1 17 ? -3.354 41.456 37.966 1.00 118.72 ? 17 ARG P O 1 +ATOM 28670 C CB . ARG P 1 17 ? -1.316 38.998 37.821 1.00 119.53 ? 17 ARG P CB 1 +ATOM 28671 C CG . ARG P 1 17 ? 0.015 38.250 37.822 1.00 108.91 ? 17 ARG P CG 1 +ATOM 28672 C CD . ARG P 1 17 ? -0.132 36.763 38.078 1.00 116.91 ? 17 ARG P CD 1 +ATOM 28673 N NE . ARG P 1 17 ? -0.331 36.468 39.487 1.00 136.85 ? 17 ARG P NE 1 +ATOM 28674 C CZ . ARG P 1 17 ? -0.666 35.269 39.956 1.00 158.73 ? 17 ARG P CZ 1 +ATOM 28675 N NH1 . ARG P 1 17 ? -0.752 34.237 39.127 1.00 142.54 ? 17 ARG P NH1 1 +ATOM 28676 N NH2 . ARG P 1 17 ? -0.851 35.095 41.264 1.00 153.24 ? 17 ARG P NH2 1 +ATOM 28677 N N . ALA P 1 18 ? -2.200 41.650 36.078 1.00 82.84 ? 18 ALA P N 1 +ATOM 28678 C CA . ALA P 1 18 ? -3.247 42.422 35.403 1.00 97.37 ? 18 ALA P CA 1 +ATOM 28679 C C . ALA P 1 18 ? -3.924 41.668 34.249 1.00 100.82 ? 18 ALA P C 1 +ATOM 28680 O O . ALA P 1 18 ? -4.550 40.635 34.470 1.00 65.40 ? 18 ALA P O 1 +ATOM 28681 C CB . ALA P 1 18 ? -2.695 43.762 34.920 1.00 126.64 ? 18 ALA P CB 1 +ATOM 28682 N N . GLN P 1 19 ? -3.801 42.186 33.021 1.00 118.27 ? 19 GLN P N 1 +ATOM 28683 C CA . GLN P 1 19 ? -4.721 41.806 31.944 1.00 139.89 ? 19 GLN P CA 1 +ATOM 28684 C C . GLN P 1 19 ? -4.484 40.370 31.476 1.00 130.07 ? 19 GLN P C 1 +ATOM 28685 O O . GLN P 1 19 ? -5.424 39.572 31.338 1.00 78.69 ? 19 GLN P O 1 +ATOM 28686 C CB . GLN P 1 19 ? -4.587 42.780 30.761 1.00 152.81 ? 19 GLN P CB 1 +ATOM 28687 C CG . GLN P 1 19 ? -5.607 42.567 29.649 1.00 154.33 ? 19 GLN P CG 1 +ATOM 28688 C CD . GLN P 1 19 ? -7.041 42.587 30.153 1.00 189.17 ? 19 GLN P CD 1 +ATOM 28689 O OE1 . GLN P 1 19 ? -7.536 43.622 30.606 1.00 235.06 ? 19 GLN P OE1 1 +ATOM 28690 N NE2 . GLN P 1 19 ? -7.710 41.437 30.102 1.00 203.86 ? 19 GLN P NE2 1 +ATOM 28691 N N . SER P 1 20 ? -3.213 40.083 31.190 1.00 133.08 ? 20 SER P N 1 +ATOM 28692 C CA . SER P 1 20 ? -2.754 38.749 30.817 1.00 115.06 ? 20 SER P CA 1 +ATOM 28693 C C . SER P 1 20 ? -3.369 37.695 31.735 1.00 107.43 ? 20 SER P C 1 +ATOM 28694 O O . SER P 1 20 ? -3.959 36.722 31.261 1.00 113.00 ? 20 SER P O 1 +ATOM 28695 C CB . SER P 1 20 ? -1.223 38.701 30.900 1.00 102.79 ? 20 SER P CB 1 +ATOM 28696 O OG . SER P 1 20 ? -0.649 39.770 30.161 1.00 133.46 ? 20 SER P OG 1 +ATOM 28697 N N . TYR P 1 21 ? -3.264 37.927 33.044 1.00 91.53 ? 21 TYR P N 1 +ATOM 28698 C CA . TYR P 1 21 ? -3.880 37.062 34.059 1.00 92.06 ? 21 TYR P CA 1 +ATOM 28699 C C . TYR P 1 21 ? -5.397 36.867 33.881 1.00 107.10 ? 21 TYR P C 1 +ATOM 28700 O O . TYR P 1 21 ? -5.895 35.731 33.865 1.00 100.14 ? 21 TYR P O 1 +ATOM 28701 C CB . TYR P 1 21 ? -3.630 37.629 35.456 1.00 94.24 ? 21 TYR P CB 1 +ATOM 28702 C CG . TYR P 1 21 ? -4.156 36.768 36.579 1.00 99.65 ? 21 TYR P CG 1 +ATOM 28703 C CD1 . TYR P 1 21 ? -3.470 35.615 36.964 1.00 155.61 ? 21 TYR P CD1 1 +ATOM 28704 C CD2 . TYR P 1 21 ? -5.328 37.088 37.249 1.00 82.18 ? 21 TYR P CD2 1 +ATOM 28705 C CE1 . TYR P 1 21 ? -3.945 34.803 37.974 1.00 155.85 ? 21 TYR P CE1 1 +ATOM 28706 C CE2 . TYR P 1 21 ? -5.793 36.300 38.284 1.00 88.36 ? 21 TYR P CE2 1 +ATOM 28707 C CZ . TYR P 1 21 ? -5.105 35.142 38.629 1.00 130.97 ? 21 TYR P CZ 1 +ATOM 28708 O OH . TYR P 1 21 ? -5.578 34.262 39.581 1.00 113.86 ? 21 TYR P OH 1 +ATOM 28709 N N . LYS P 1 22 ? -6.121 37.971 33.716 1.00 131.68 ? 22 LYS P N 1 +ATOM 28710 C CA . LYS P 1 22 ? -7.572 37.930 33.560 1.00 130.47 ? 22 LYS P CA 1 +ATOM 28711 C C . LYS P 1 22 ? -8.009 37.124 32.335 1.00 113.75 ? 22 LYS P C 1 +ATOM 28712 O O . LYS P 1 22 ? -8.979 36.362 32.394 1.00 71.63 ? 22 LYS P O 1 +ATOM 28713 C CB . LYS P 1 22 ? -8.133 39.354 33.447 1.00 149.49 ? 22 LYS P CB 1 +ATOM 28714 C CG . LYS P 1 22 ? -8.452 40.012 34.781 1.00 146.50 ? 22 LYS P CG 1 +ATOM 28715 C CD . LYS P 1 22 ? -9.910 40.016 35.178 1.00 134.88 ? 22 LYS P CD 1 +ATOM 28716 C CE . LYS P 1 22 ? -9.974 39.999 36.696 1.00 115.85 ? 22 LYS P CE 1 +ATOM 28717 N NZ . LYS P 1 22 ? -9.590 38.663 37.212 1.00 132.73 ? 22 LYS P NZ 1 +ATOM 28718 N N . ASP P 1 23 ? -7.303 37.319 31.227 1.00 101.10 ? 23 ASP P N 1 +ATOM 28719 C CA . ASP P 1 23 ? -7.505 36.496 30.048 1.00 113.44 ? 23 ASP P CA 1 +ATOM 28720 C C . ASP P 1 23 ? -7.214 35.019 30.337 1.00 106.49 ? 23 ASP P C 1 +ATOM 28721 O O . ASP P 1 23 ? -7.959 34.127 29.914 1.00 96.37 ? 23 ASP P O 1 +ATOM 28722 C CB . ASP P 1 23 ? -6.605 36.988 28.900 1.00 132.25 ? 23 ASP P CB 1 +ATOM 28723 C CG . ASP P 1 23 ? -6.998 38.352 28.417 1.00 147.12 ? 23 ASP P CG 1 +ATOM 28724 O OD1 . ASP P 1 23 ? -8.218 38.590 28.297 1.00 167.75 ? 23 ASP P OD1 1 +ATOM 28725 O OD2 . ASP P 1 23 ? -6.097 39.168 28.133 1.00 159.73 ? 23 ASP P OD2 1 +ATOM 28726 N N . LEU P 1 24 ? -6.080 34.771 30.989 1.00 93.80 ? 24 LEU P N 1 +ATOM 28727 C CA . LEU P 1 24 ? -5.560 33.418 31.198 1.00 98.43 ? 24 LEU P CA 1 +ATOM 28728 C C . LEU P 1 24 ? -6.487 32.587 32.090 1.00 101.42 ? 24 LEU P C 1 +ATOM 28729 O O . LEU P 1 24 ? -6.639 31.371 31.880 1.00 102.53 ? 24 LEU P O 1 +ATOM 28730 C CB . LEU P 1 24 ? -4.165 33.493 31.827 1.00 117.13 ? 24 LEU P CB 1 +ATOM 28731 C CG . LEU P 1 24 ? -3.438 32.179 32.151 1.00 123.23 ? 24 LEU P CG 1 +ATOM 28732 C CD1 . LEU P 1 24 ? -2.671 31.672 30.936 1.00 122.11 ? 24 LEU P CD1 1 +ATOM 28733 C CD2 . LEU P 1 24 ? -2.502 32.370 33.345 1.00 110.36 ? 24 LEU P CD2 1 +ATOM 28734 N N . THR P 1 25 ? -7.122 33.252 33.060 1.00 116.81 ? 25 THR P N 1 +ATOM 28735 C CA . THR P 1 25 ? -8.017 32.576 34.018 1.00 139.78 ? 25 THR P CA 1 +ATOM 28736 C C . THR P 1 25 ? -9.375 32.231 33.405 1.00 168.70 ? 25 THR P C 1 +ATOM 28737 O O . THR P 1 25 ? -9.839 31.094 33.511 1.00 163.82 ? 25 THR P O 1 +ATOM 28738 C CB . THR P 1 25 ? -8.251 33.433 35.272 1.00 125.18 ? 25 THR P CB 1 +ATOM 28739 O OG1 . THR P 1 25 ? -8.528 34.788 34.888 1.00 126.89 ? 25 THR P OG1 1 +ATOM 28740 C CG2 . THR P 1 25 ? -7.021 33.412 36.141 1.00 149.22 ? 25 THR P CG2 1 +ATOM 28741 N N . HIS P 1 26 ? -9.960 33.196 32.697 1.00 174.59 ? 26 HIS P N 1 +ATOM 28742 C CA . HIS P 1 26 ? -11.273 33.026 32.074 1.00 141.35 ? 26 HIS P CA 1 +ATOM 28743 C C . HIS P 1 26 ? -11.187 32.351 30.698 1.00 156.79 ? 26 HIS P C 1 +ATOM 28744 O O . HIS P 1 26 ? -11.923 32.690 29.772 1.00 186.94 ? 26 HIS P O 1 +ATOM 28745 C CB . HIS P 1 26 ? -11.973 34.389 31.991 1.00 161.85 ? 26 HIS P CB 1 +ATOM 28746 C CG . HIS P 1 26 ? -12.259 34.993 33.340 1.00 176.89 ? 26 HIS P CG 1 +ATOM 28747 N ND1 . HIS P 1 26 ? -11.266 35.475 34.169 1.00 184.57 ? 26 HIS P ND1 1 +ATOM 28748 C CD2 . HIS P 1 26 ? -13.422 35.157 34.020 1.00 165.70 ? 26 HIS P CD2 1 +ATOM 28749 C CE1 . HIS P 1 26 ? -11.806 35.928 35.286 1.00 151.49 ? 26 HIS P CE1 1 +ATOM 28750 N NE2 . HIS P 1 26 ? -13.112 35.747 35.223 1.00 145.68 ? 26 HIS P NE2 1 +ATOM 28751 N N . LEU P 1 27 ? -10.269 31.403 30.552 1.00 169.27 ? 27 LEU P N 1 +ATOM 28752 C CA . LEU P 1 27 ? -10.168 30.630 29.315 1.00 153.72 ? 27 LEU P CA 1 +ATOM 28753 C C . LEU P 1 27 ? -11.079 29.408 29.409 1.00 151.57 ? 27 LEU P C 1 +ATOM 28754 O O . LEU P 1 27 ? -11.103 28.733 30.435 1.00 138.81 ? 27 LEU P O 1 +ATOM 28755 C CB . LEU P 1 27 ? -8.726 30.182 29.064 1.00 133.54 ? 27 LEU P CB 1 +ATOM 28756 C CG . LEU P 1 27 ? -7.857 31.169 28.286 1.00 135.19 ? 27 LEU P CG 1 +ATOM 28757 C CD1 . LEU P 1 27 ? -6.386 30.777 28.368 1.00 157.63 ? 27 LEU P CD1 1 +ATOM 28758 C CD2 . LEU P 1 27 ? -8.294 31.262 26.834 1.00 139.13 ? 27 LEU P CD2 1 +ATOM 28759 N N . PRO P 1 28 ? -11.823 29.114 28.329 1.00 127.87 ? 28 PRO P N 1 +ATOM 28760 C CA . PRO P 1 28 ? -12.750 27.976 28.301 1.00 131.41 ? 28 PRO P CA 1 +ATOM 28761 C C . PRO P 1 28 ? -12.035 26.661 28.513 1.00 148.42 ? 28 PRO P C 1 +ATOM 28762 O O . PRO P 1 28 ? -11.026 26.417 27.866 1.00 189.93 ? 28 PRO P O 1 +ATOM 28763 C CB . PRO P 1 28 ? -13.322 28.023 26.885 1.00 145.74 ? 28 PRO P CB 1 +ATOM 28764 C CG . PRO P 1 28 ? -12.308 28.775 26.082 1.00 136.67 ? 28 PRO P CG 1 +ATOM 28765 C CD . PRO P 1 28 ? -11.733 29.788 27.021 1.00 128.06 ? 28 PRO P CD 1 +ATOM 28766 N N . ALA P 1 29 ? -12.525 25.838 29.437 1.00 159.07 ? 29 ALA P N 1 +ATOM 28767 C CA . ALA P 1 29 ? -11.754 24.687 29.925 1.00 161.02 ? 29 ALA P CA 1 +ATOM 28768 C C . ALA P 1 29 ? -11.704 23.542 28.895 1.00 150.68 ? 29 ALA P C 1 +ATOM 28769 O O . ALA P 1 29 ? -12.617 23.386 28.088 1.00 130.86 ? 29 ALA P O 1 +ATOM 28770 C CB . ALA P 1 29 ? -12.309 24.196 31.259 1.00 128.86 ? 29 ALA P CB 1 +ATOM 28771 N N . PRO P 1 30 ? -10.584 22.796 28.867 1.00 157.45 ? 30 PRO P N 1 +ATOM 28772 C CA . PRO P 1 30 ? -10.420 21.639 27.982 1.00 135.60 ? 30 PRO P CA 1 +ATOM 28773 C C . PRO P 1 30 ? -11.192 20.426 28.497 1.00 110.13 ? 30 PRO P C 1 +ATOM 28774 O O . PRO P 1 30 ? -11.740 20.474 29.609 1.00 81.24 ? 30 PRO P O 1 +ATOM 28775 C CB . PRO P 1 30 ? -8.923 21.361 28.062 1.00 157.92 ? 30 PRO P CB 1 +ATOM 28776 C CG . PRO P 1 30 ? -8.519 21.832 29.423 1.00 150.04 ? 30 PRO P CG 1 +ATOM 28777 C CD . PRO P 1 30 ? -9.417 22.987 29.755 1.00 158.59 ? 30 PRO P CD 1 +ATOM 28778 N N . THR P 1 31 ? -11.173 19.330 27.735 1.00 93.41 ? 31 THR P N 1 +ATOM 28779 C CA . THR P 1 31 ? -11.896 18.099 28.130 1.00 118.83 ? 31 THR P CA 1 +ATOM 28780 C C . THR P 1 31 ? -11.290 17.418 29.361 1.00 117.49 ? 31 THR P C 1 +ATOM 28781 O O . THR P 1 31 ? -11.982 16.734 30.109 1.00 103.17 ? 31 THR P O 1 +ATOM 28782 C CB . THR P 1 31 ? -11.994 17.060 26.984 1.00 121.93 ? 31 THR P CB 1 +ATOM 28783 O OG1 . THR P 1 31 ? -10.695 16.782 26.448 1.00 152.32 ? 31 THR P OG1 1 +ATOM 28784 C CG2 . THR P 1 31 ? -12.899 17.566 25.866 1.00 129.25 ? 31 THR P CG2 1 +ATOM 28785 N N . GLY P 1 32 ? -9.992 17.610 29.557 1.00 143.91 ? 32 GLY P N 1 +ATOM 28786 C CA . GLY P 1 32 ? -9.326 17.249 30.810 1.00 139.11 ? 32 GLY P CA 1 +ATOM 28787 C C . GLY P 1 32 ? -8.057 18.066 30.947 1.00 123.39 ? 32 GLY P C 1 +ATOM 28788 O O . GLY P 1 32 ? -7.542 18.569 29.941 1.00 144.66 ? 32 GLY P O 1 +ATOM 28789 N N . LYS P 1 33 ? -7.593 18.280 32.175 1.00 86.16 ? 33 LYS P N 1 +ATOM 28790 C CA . LYS P 1 33 ? -6.362 19.038 32.355 1.00 102.04 ? 33 LYS P CA 1 +ATOM 28791 C C . LYS P 1 33 ? -5.174 18.220 31.832 1.00 121.94 ? 33 LYS P C 1 +ATOM 28792 O O . LYS P 1 33 ? -5.225 16.992 31.825 1.00 113.36 ? 33 LYS P O 1 +ATOM 28793 C CB . LYS P 1 33 ? -6.148 19.426 33.813 1.00 95.51 ? 33 LYS P CB 1 +ATOM 28794 C CG . LYS P 1 33 ? -6.728 20.771 34.193 1.00 97.05 ? 33 LYS P CG 1 +ATOM 28795 C CD . LYS P 1 33 ? -6.629 20.988 35.692 1.00 99.73 ? 33 LYS P CD 1 +ATOM 28796 C CE . LYS P 1 33 ? -7.700 21.940 36.164 1.00 123.30 ? 33 LYS P CE 1 +ATOM 28797 N NZ . LYS P 1 33 ? -7.727 22.039 37.644 1.00 145.72 ? 33 LYS P NZ 1 +ATOM 28798 N N . ILE P 1 34 ? -4.131 18.906 31.363 1.00 142.18 ? 34 ILE P N 1 +ATOM 28799 C CA . ILE P 1 34 ? -2.980 18.239 30.765 1.00 137.49 ? 34 ILE P CA 1 +ATOM 28800 C C . ILE P 1 34 ? -1.815 18.314 31.760 1.00 151.02 ? 34 ILE P C 1 +ATOM 28801 O O . ILE P 1 34 ? -1.706 19.272 32.541 1.00 179.00 ? 34 ILE P O 1 +ATOM 28802 C CB . ILE P 1 34 ? -2.642 18.838 29.367 1.00 127.82 ? 34 ILE P CB 1 +ATOM 28803 C CG1 . ILE P 1 34 ? -3.767 18.538 28.376 1.00 114.71 ? 34 ILE P CG1 1 +ATOM 28804 C CG2 . ILE P 1 34 ? -1.358 18.258 28.797 1.00 142.70 ? 34 ILE P CG2 1 +ATOM 28805 C CD1 . ILE P 1 34 ? -4.435 19.774 27.838 1.00 123.98 ? 34 ILE P CD1 1 +ATOM 28806 N N . PHE P 1 35 ? -1.064 17.221 31.836 1.00 135.93 ? 35 PHE P N 1 +ATOM 28807 C CA . PHE P 1 35 ? 0.058 17.098 32.747 1.00 114.67 ? 35 PHE P CA 1 +ATOM 28808 C C . PHE P 1 35 ? 1.283 17.738 32.132 1.00 116.45 ? 35 PHE P C 1 +ATOM 28809 O O . PHE P 1 35 ? 1.702 17.345 31.051 1.00 133.55 ? 35 PHE P O 1 +ATOM 28810 C CB . PHE P 1 35 ? 0.348 15.629 32.979 1.00 100.34 ? 35 PHE P CB 1 +ATOM 28811 C CG . PHE P 1 35 ? -0.481 15.008 34.066 1.00 87.48 ? 35 PHE P CG 1 +ATOM 28812 C CD1 . PHE P 1 35 ? -0.634 15.625 35.304 1.00 69.19 ? 35 PHE P CD1 1 +ATOM 28813 C CD2 . PHE P 1 35 ? -0.988 13.731 33.893 1.00 110.14 ? 35 PHE P CD2 1 +ATOM 28814 C CE1 . PHE P 1 35 ? -1.319 15.005 36.327 1.00 76.74 ? 35 PHE P CE1 1 +ATOM 28815 C CE2 . PHE P 1 35 ? -1.665 13.095 34.919 1.00 112.15 ? 35 PHE P CE2 1 +ATOM 28816 C CZ . PHE P 1 35 ? -1.839 13.735 36.134 1.00 107.80 ? 35 PHE P CZ 1 +ATOM 28817 N N . VAL P 1 36 ? 1.916 18.653 32.857 1.00 126.34 ? 36 VAL P N 1 +ATOM 28818 C CA . VAL P 1 36 ? 3.060 19.376 32.299 1.00 122.99 ? 36 VAL P CA 1 +ATOM 28819 C C . VAL P 1 36 ? 4.272 19.398 33.253 1.00 91.53 ? 36 VAL P C 1 +ATOM 28820 O O . VAL P 1 36 ? 4.107 19.424 34.456 1.00 93.49 ? 36 VAL P O 1 +ATOM 28821 C CB . VAL P 1 36 ? 2.648 20.810 31.910 1.00 106.83 ? 36 VAL P CB 1 +ATOM 28822 C CG1 . VAL P 1 36 ? 2.518 21.685 33.158 1.00 113.26 ? 36 VAL P CG1 1 +ATOM 28823 C CG2 . VAL P 1 36 ? 3.647 21.393 30.935 1.00 91.06 ? 36 VAL P CG2 1 +ATOM 28824 N N . SER P 1 37 ? 5.462 19.468 32.684 1.00 58.51 ? 37 SER P N 1 +ATOM 28825 C CA . SER P 1 37 ? 6.651 19.583 33.460 1.00 50.91 ? 37 SER P CA 1 +ATOM 28826 C C . SER P 1 37 ? 7.414 20.799 33.076 1.00 51.61 ? 37 SER P C 1 +ATOM 28827 O O . SER P 1 37 ? 7.613 21.095 31.881 1.00 82.87 ? 37 SER P O 1 +ATOM 28828 C CB . SER P 1 37 ? 7.523 18.410 33.136 1.00 75.99 ? 37 SER P CB 1 +ATOM 28829 O OG . SER P 1 37 ? 7.043 17.217 33.715 1.00 120.15 ? 37 SER P OG 1 +ATOM 28830 N N . VAL P 1 38 ? 7.877 21.548 34.044 1.00 66.14 ? 38 VAL P N 1 +ATOM 28831 C CA . VAL P 1 38 ? 8.830 22.633 33.724 1.00 118.39 ? 38 VAL P CA 1 +ATOM 28832 C C . VAL P 1 38 ? 10.099 22.431 34.531 1.00 129.16 ? 38 VAL P C 1 +ATOM 28833 O O . VAL P 1 38 ? 10.053 22.447 35.775 1.00 171.79 ? 38 VAL P O 1 +ATOM 28834 C CB . VAL P 1 38 ? 8.294 24.051 34.065 1.00 163.97 ? 38 VAL P CB 1 +ATOM 28835 C CG1 . VAL P 1 38 ? 9.360 25.105 33.785 1.00 170.22 ? 38 VAL P CG1 1 +ATOM 28836 C CG2 . VAL P 1 38 ? 7.023 24.380 33.296 1.00 145.35 ? 38 VAL P CG2 1 +ATOM 28837 N N . TYR P 1 39 ? 11.225 22.286 33.832 1.00 94.90 ? 39 TYR P N 1 +ATOM 28838 C CA . TYR P 1 39 ? 12.493 22.009 34.489 1.00 83.25 ? 39 TYR P CA 1 +ATOM 28839 C C . TYR P 1 39 ? 13.163 23.357 34.771 1.00 74.27 ? 39 TYR P C 1 +ATOM 28840 O O . TYR P 1 39 ? 13.622 23.610 35.884 1.00 61.21 ? 39 TYR P O 1 +ATOM 28841 C CB . TYR P 1 39 ? 13.366 21.027 33.641 1.00 88.29 ? 39 TYR P CB 1 +ATOM 28842 C CG . TYR P 1 39 ? 13.069 19.526 33.883 1.00 85.60 ? 39 TYR P CG 1 +ATOM 28843 C CD1 . TYR P 1 39 ? 11.912 18.923 33.348 1.00 98.15 ? 39 TYR P CD1 1 +ATOM 28844 C CD2 . TYR P 1 39 ? 13.924 18.722 34.633 1.00 76.02 ? 39 TYR P CD2 1 +ATOM 28845 C CE1 . TYR P 1 39 ? 11.616 17.569 33.563 1.00 65.77 ? 39 TYR P CE1 1 +ATOM 28846 C CE2 . TYR P 1 39 ? 13.614 17.379 34.889 1.00 70.70 ? 39 TYR P CE2 1 +ATOM 28847 C CZ . TYR P 1 39 ? 12.463 16.802 34.347 1.00 63.48 ? 39 TYR P CZ 1 +ATOM 28848 O OH . TYR P 1 39 ? 12.154 15.496 34.608 1.00 34.43 ? 39 TYR P OH 1 +ATOM 28849 N N . ASN P 1 40 ? 13.313 24.186 33.742 1.00 81.66 ? 40 ASN P N 1 +ATOM 28850 C CA . ASN P 1 40 ? 14.072 25.444 33.892 1.00 88.69 ? 40 ASN P CA 1 +ATOM 28851 C C . ASN P 1 40 ? 13.957 26.429 32.713 1.00 98.36 ? 40 ASN P C 1 +ATOM 28852 O O . ASN P 1 40 ? 14.073 26.041 31.551 1.00 109.00 ? 40 ASN P O 1 +ATOM 28853 C CB . ASN P 1 40 ? 15.556 25.165 34.105 1.00 88.92 ? 40 ASN P CB 1 +ATOM 28854 C CG . ASN P 1 40 ? 16.267 26.311 34.752 1.00 90.39 ? 40 ASN P CG 1 +ATOM 28855 O OD1 . ASN P 1 40 ? 15.917 26.749 35.856 1.00 72.36 ? 40 ASN P OD1 1 +ATOM 28856 N ND2 . ASN P 1 40 ? 17.259 26.844 34.046 1.00 126.30 ? 40 ASN P ND2 1 +ATOM 28857 N N . ILE P 1 41 ? 13.647 27.687 33.032 1.00 81.35 ? 41 ILE P N 1 +ATOM 28858 C CA . ILE P 1 41 ? 13.664 28.760 32.051 1.00 70.95 ? 41 ILE P CA 1 +ATOM 28859 C C . ILE P 1 41 ? 14.723 29.770 32.468 1.00 63.40 ? 41 ILE P C 1 +ATOM 28860 O O . ILE P 1 41 ? 14.602 30.408 33.515 1.00 44.39 ? 41 ILE P O 1 +ATOM 28861 C CB . ILE P 1 41 ? 12.284 29.455 31.913 1.00 85.48 ? 41 ILE P CB 1 +ATOM 28862 C CG1 . ILE P 1 41 ? 11.319 28.647 31.026 1.00 89.98 ? 41 ILE P CG1 1 +ATOM 28863 C CG2 . ILE P 1 41 ? 12.443 30.808 31.237 1.00 91.99 ? 41 ILE P CG2 1 +ATOM 28864 C CD1 . ILE P 1 41 ? 10.788 27.350 31.625 1.00 71.11 ? 41 ILE P CD1 1 +ATOM 28865 N N . GLN P 1 42 ? 15.757 29.922 31.647 1.00 67.68 ? 42 GLN P N 1 +ATOM 28866 C CA . GLN P 1 42 ? 16.957 30.685 32.052 1.00 77.49 ? 42 GLN P CA 1 +ATOM 28867 C C . GLN P 1 42 ? 16.872 32.144 31.711 1.00 77.31 ? 42 GLN P C 1 +ATOM 28868 O O . GLN P 1 42 ? 16.121 32.550 30.800 1.00 111.70 ? 42 GLN P O 1 +ATOM 28869 C CB . GLN P 1 42 ? 18.206 30.133 31.374 1.00 114.13 ? 42 GLN P CB 1 +ATOM 28870 C CG . GLN P 1 42 ? 18.564 28.719 31.791 1.00 139.14 ? 42 GLN P CG 1 +ATOM 28871 C CD . GLN P 1 42 ? 18.542 27.739 30.621 1.00 159.29 ? 42 GLN P CD 1 +ATOM 28872 O OE1 . GLN P 1 42 ? 19.548 27.586 29.908 1.00 153.60 ? 42 GLN P OE1 1 +ATOM 28873 N NE2 . GLN P 1 42 ? 17.382 27.104 30.383 1.00 116.30 ? 42 GLN P NE2 1 +ATOM 28874 N N . ASP P 1 43 ? 17.649 32.943 32.432 1.00 70.59 ? 43 ASP P N 1 +ATOM 28875 C CA . ASP P 1 43 ? 17.855 34.368 32.094 1.00 86.25 ? 43 ASP P CA 1 +ATOM 28876 C C . ASP P 1 43 ? 18.887 34.507 30.956 1.00 65.66 ? 43 ASP P C 1 +ATOM 28877 O O . ASP P 1 43 ? 19.976 35.043 31.181 1.00 43.51 ? 43 ASP P O 1 +ATOM 28878 C CB . ASP P 1 43 ? 18.319 35.148 33.355 1.00 78.39 ? 43 ASP P CB 1 +ATOM 28879 C CG . ASP P 1 43 ? 18.330 36.677 33.159 1.00 95.93 ? 43 ASP P CG 1 +ATOM 28880 O OD1 . ASP P 1 43 ? 17.325 37.212 32.623 1.00 158.08 ? 43 ASP P OD1 1 +ATOM 28881 O OD2 . ASP P 1 43 ? 19.356 37.337 33.428 1.00 55.85 ? 43 ASP P OD2 1 +ATOM 28882 N N . GLU P 1 44 ? 18.541 33.992 29.778 1.00 51.21 ? 44 GLU P N 1 +ATOM 28883 C CA . GLU P 1 44 ? 19.458 33.982 28.669 1.00 59.29 ? 44 GLU P CA 1 +ATOM 28884 C C . GLU P 1 44 ? 19.790 35.420 28.165 1.00 60.60 ? 44 GLU P C 1 +ATOM 28885 O O . GLU P 1 44 ? 20.285 35.589 27.006 1.00 42.62 ? 44 GLU P O 1 +ATOM 28886 C CB . GLU P 1 44 ? 18.923 33.074 27.531 1.00 75.85 ? 44 GLU P CB 1 +ATOM 28887 C CG . GLU P 1 44 ? 19.324 31.597 27.635 1.00 99.14 ? 44 GLU P CG 1 +ATOM 28888 C CD . GLU P 1 44 ? 18.736 30.691 26.515 1.00 128.09 ? 44 GLU P CD 1 +ATOM 28889 O OE1 . GLU P 1 44 ? 18.787 31.044 25.305 1.00 133.19 ? 44 GLU P OE1 1 +ATOM 28890 O OE2 . GLU P 1 44 ? 18.300 29.550 26.834 1.00 106.46 ? 44 GLU P OE2 1 +ATOM 28891 N N . THR P 1 45 ? 19.489 36.445 28.983 1.00 48.96 ? 45 THR P N 1 +ATOM 28892 C CA . THR P 1 45 ? 19.409 37.849 28.480 1.00 57.87 ? 45 THR P CA 1 +ATOM 28893 C C . THR P 1 45 ? 20.747 38.517 28.399 1.00 51.50 ? 45 THR P C 1 +ATOM 28894 O O . THR P 1 45 ? 21.054 39.189 27.420 1.00 31.82 ? 45 THR P O 1 +ATOM 28895 C CB . THR P 1 45 ? 18.453 38.728 29.310 1.00 66.90 ? 45 THR P CB 1 +ATOM 28896 O OG1 . THR P 1 45 ? 18.232 39.974 28.637 1.00 77.93 ? 45 THR P OG1 1 +ATOM 28897 C CG2 . THR P 1 45 ? 19.004 39.004 30.680 1.00 66.20 ? 45 THR P CG2 1 +ATOM 28898 N N . GLY P 1 46 ? 21.601 38.194 29.359 1.00 69.33 ? 46 GLY P N 1 +ATOM 28899 C CA . GLY P 1 46 ? 23.031 38.591 29.285 1.00 99.31 ? 46 GLY P CA 1 +ATOM 28900 C C . GLY P 1 46 ? 23.284 39.985 29.869 1.00 110.02 ? 46 GLY P C 1 +ATOM 28901 O O . GLY P 1 46 ? 24.291 40.651 29.634 1.00 55.41 ? 46 GLY P O 1 +ATOM 28902 N N . GLN P 1 47 ? 22.380 40.415 30.715 1.00 141.89 ? 47 GLN P N 1 +ATOM 28903 C CA . GLN P 1 47 ? 22.327 41.802 30.975 1.00 133.18 ? 47 GLN P CA 1 +ATOM 28904 C C . GLN P 1 47 ? 22.212 42.102 32.455 1.00 105.41 ? 47 GLN P C 1 +ATOM 28905 O O . GLN P 1 47 ? 21.505 41.419 33.204 1.00 98.65 ? 47 GLN P O 1 +ATOM 28906 C CB . GLN P 1 47 ? 21.172 42.379 30.201 1.00 135.59 ? 47 GLN P CB 1 +ATOM 28907 C CG . GLN P 1 47 ? 21.385 42.363 28.691 1.00 104.86 ? 47 GLN P CG 1 +ATOM 28908 C CD . GLN P 1 47 ? 22.719 42.941 28.295 1.00 85.05 ? 47 GLN P CD 1 +ATOM 28909 O OE1 . GLN P 1 47 ? 22.924 44.146 28.370 1.00 80.12 ? 47 GLN P OE1 1 +ATOM 28910 N NE2 . GLN P 1 47 ? 23.613 42.103 27.868 1.00 81.14 ? 47 GLN P NE2 1 +ATOM 28911 N N . PHE P 1 48 ? 22.945 43.126 32.847 1.00 99.84 ? 48 PHE P N 1 +ATOM 28912 C CA . PHE P 1 48 ? 22.984 43.572 34.214 1.00 109.79 ? 48 PHE P CA 1 +ATOM 28913 C C . PHE P 1 48 ? 22.644 45.045 34.271 1.00 117.51 ? 48 PHE P C 1 +ATOM 28914 O O . PHE P 1 48 ? 22.700 45.768 33.266 1.00 115.54 ? 48 PHE P O 1 +ATOM 28915 C CB . PHE P 1 48 ? 24.380 43.333 34.825 1.00 130.22 ? 48 PHE P CB 1 +ATOM 28916 C CG . PHE P 1 48 ? 24.715 41.900 34.968 1.00 135.80 ? 48 PHE P CG 1 +ATOM 28917 C CD1 . PHE P 1 48 ? 25.061 41.161 33.857 1.00 126.10 ? 48 PHE P CD1 1 +ATOM 28918 C CD2 . PHE P 1 48 ? 24.599 41.275 36.186 1.00 139.78 ? 48 PHE P CD2 1 +ATOM 28919 C CE1 . PHE P 1 48 ? 25.271 39.814 33.951 1.00 119.85 ? 48 PHE P CE1 1 +ATOM 28920 C CE2 . PHE P 1 48 ? 24.835 39.930 36.293 1.00 141.05 ? 48 PHE P CE2 1 +ATOM 28921 C CZ . PHE P 1 48 ? 25.188 39.202 35.179 1.00 131.44 ? 48 PHE P CZ 1 +ATOM 28922 N N . LYS P 1 49 ? 22.416 45.510 35.493 1.00 122.33 ? 49 LYS P N 1 +ATOM 28923 C CA . LYS P 1 49 ? 22.042 46.903 35.722 1.00 92.43 ? 49 LYS P CA 1 +ATOM 28924 C C . LYS P 1 49 ? 23.285 47.766 35.670 1.00 86.75 ? 49 LYS P C 1 +ATOM 28925 O O . LYS P 1 49 ? 24.377 47.332 36.059 1.00 109.32 ? 49 LYS P O 1 +ATOM 28926 C CB . LYS P 1 49 ? 21.296 47.066 37.055 1.00 82.32 ? 49 LYS P CB 1 +ATOM 28927 C CG . LYS P 1 49 ? 19.955 46.343 37.062 1.00 78.17 ? 49 LYS P CG 1 +ATOM 28928 C CD . LYS P 1 49 ? 19.040 46.592 38.250 1.00 69.75 ? 49 LYS P CD 1 +ATOM 28929 C CE . LYS P 1 49 ? 17.703 45.892 37.936 1.00 77.49 ? 49 LYS P CE 1 +ATOM 28930 N NZ . LYS P 1 49 ? 16.620 46.059 38.941 1.00 75.24 ? 49 LYS P NZ 1 +ATOM 28931 N N . PRO P 1 50 ? 23.126 48.992 35.170 1.00 92.39 ? 50 PRO P N 1 +ATOM 28932 C CA . PRO P 1 50 ? 24.241 49.922 35.067 1.00 105.90 ? 50 PRO P CA 1 +ATOM 28933 C C . PRO P 1 50 ? 24.563 50.582 36.413 1.00 127.74 ? 50 PRO P C 1 +ATOM 28934 O O . PRO P 1 50 ? 23.741 50.529 37.353 1.00 157.35 ? 50 PRO P O 1 +ATOM 28935 C CB . PRO P 1 50 ? 23.737 50.952 34.039 1.00 99.88 ? 50 PRO P CB 1 +ATOM 28936 C CG . PRO P 1 50 ? 22.251 50.925 34.175 1.00 91.41 ? 50 PRO P CG 1 +ATOM 28937 C CD . PRO P 1 50 ? 21.891 49.518 34.553 1.00 91.79 ? 50 PRO P CD 1 +ATOM 28938 N N . TYR P 1 51 ? 25.711 51.254 36.480 1.00 129.56 ? 51 TYR P N 1 +ATOM 28939 C CA . TYR P 1 51 ? 25.992 52.120 37.604 1.00 126.44 ? 51 TYR P CA 1 +ATOM 28940 C C . TYR P 1 51 ? 24.807 53.057 37.879 1.00 153.45 ? 51 TYR P C 1 +ATOM 28941 O O . TYR P 1 51 ? 24.242 53.630 36.942 1.00 179.85 ? 51 TYR P O 1 +ATOM 28942 C CB . TYR P 1 51 ? 27.246 52.954 37.363 1.00 124.88 ? 51 TYR P CB 1 +ATOM 28943 C CG . TYR P 1 51 ? 27.755 53.551 38.660 1.00 149.24 ? 51 TYR P CG 1 +ATOM 28944 C CD1 . TYR P 1 51 ? 28.567 52.804 39.506 1.00 137.06 ? 51 TYR P CD1 1 +ATOM 28945 C CD2 . TYR P 1 51 ? 27.393 54.838 39.069 1.00 183.31 ? 51 TYR P CD2 1 +ATOM 28946 C CE1 . TYR P 1 51 ? 29.042 53.309 40.707 1.00 124.44 ? 51 TYR P CE1 1 +ATOM 28947 C CE2 . TYR P 1 51 ? 27.885 55.365 40.274 1.00 178.73 ? 51 TYR P CE2 1 +ATOM 28948 C CZ . TYR P 1 51 ? 28.683 54.567 41.096 1.00 154.10 ? 51 TYR P CZ 1 +ATOM 28949 O OH . TYR P 1 51 ? 29.187 55.018 42.290 1.00 185.44 ? 51 TYR P OH 1 +ATOM 28950 N N . PRO P 1 52 ? 24.407 53.215 39.162 1.00 148.52 ? 52 PRO P N 1 +ATOM 28951 C CA . PRO P 1 52 ? 25.043 52.746 40.394 1.00 138.69 ? 52 PRO P CA 1 +ATOM 28952 C C . PRO P 1 52 ? 24.624 51.392 40.950 1.00 129.54 ? 52 PRO P C 1 +ATOM 28953 O O . PRO P 1 52 ? 24.865 51.139 42.135 1.00 130.79 ? 52 PRO P O 1 +ATOM 28954 C CB . PRO P 1 52 ? 24.663 53.843 41.387 1.00 140.55 ? 52 PRO P CB 1 +ATOM 28955 C CG . PRO P 1 52 ? 23.292 54.261 40.947 1.00 122.78 ? 52 PRO P CG 1 +ATOM 28956 C CD . PRO P 1 52 ? 23.288 54.143 39.449 1.00 126.39 ? 52 PRO P CD 1 +ATOM 28957 N N . ALA P 1 53 ? 24.001 50.539 40.138 1.00 105.71 ? 53 ALA P N 1 +ATOM 28958 C CA . ALA P 1 53 ? 23.598 49.217 40.628 1.00 97.54 ? 53 ALA P CA 1 +ATOM 28959 C C . ALA P 1 53 ? 24.803 48.395 40.904 1.00 86.91 ? 53 ALA P C 1 +ATOM 28960 O O . ALA P 1 53 ? 25.940 48.716 40.465 1.00 72.73 ? 53 ALA P O 1 +ATOM 28961 C CB . ALA P 1 53 ? 22.741 48.480 39.632 1.00 109.33 ? 53 ALA P CB 1 +ATOM 28962 N N . SER P 1 54 ? 24.600 47.351 41.694 1.00 86.86 ? 54 SER P N 1 +ATOM 28963 C CA . SER P 1 54 ? 25.718 46.449 41.903 1.00 143.82 ? 54 SER P CA 1 +ATOM 28964 C C . SER P 1 54 ? 26.074 45.882 40.538 1.00 124.70 ? 54 SER P C 1 +ATOM 28965 O O . SER P 1 54 ? 25.200 45.592 39.725 1.00 106.23 ? 54 SER P O 1 +ATOM 28966 C CB . SER P 1 54 ? 25.389 45.335 42.908 1.00 180.86 ? 54 SER P CB 1 +ATOM 28967 O OG . SER P 1 54 ? 26.201 44.176 42.724 1.00 186.94 ? 54 SER P OG 1 +ATOM 28968 N N . ASN P 1 55 ? 27.374 45.687 40.321 1.00 118.82 ? 55 ASN P N 1 +ATOM 28969 C CA . ASN P 1 55 ? 27.873 45.018 39.137 1.00 99.55 ? 55 ASN P CA 1 +ATOM 28970 C C . ASN P 1 55 ? 27.145 43.690 38.847 1.00 104.14 ? 55 ASN P C 1 +ATOM 28971 O O . ASN P 1 55 ? 26.959 43.300 37.682 1.00 104.08 ? 55 ASN P O 1 +ATOM 28972 C CB . ASN P 1 55 ? 29.352 44.748 39.313 1.00 77.25 ? 55 ASN P CB 1 +ATOM 28973 C CG . ASN P 1 55 ? 30.036 44.507 38.009 1.00 106.73 ? 55 ASN P CG 1 +ATOM 28974 O OD1 . ASN P 1 55 ? 29.540 44.829 36.925 1.00 115.65 ? 55 ASN P OD1 1 +ATOM 28975 N ND2 . ASN P 1 55 ? 31.196 43.939 38.105 1.00 144.92 ? 55 ASN P ND2 1 +ATOM 28976 N N . PHE P 1 56 ? 26.661 43.055 39.918 1.00 110.87 ? 56 PHE P N 1 +ATOM 28977 C CA . PHE P 1 56 ? 26.090 41.717 39.855 1.00 84.75 ? 56 PHE P CA 1 +ATOM 28978 C C . PHE P 1 56 ? 24.583 41.732 39.783 1.00 94.11 ? 56 PHE P C 1 +ATOM 28979 O O . PHE P 1 56 ? 23.961 40.676 39.783 1.00 133.68 ? 56 PHE P O 1 +ATOM 28980 C CB . PHE P 1 56 ? 26.442 40.924 41.113 1.00 100.08 ? 56 PHE P CB 1 +ATOM 28981 C CG . PHE P 1 56 ? 27.917 40.791 41.371 1.00 120.20 ? 56 PHE P CG 1 +ATOM 28982 C CD1 . PHE P 1 56 ? 28.759 40.139 40.460 1.00 137.57 ? 56 PHE P CD1 1 +ATOM 28983 C CD2 . PHE P 1 56 ? 28.465 41.318 42.520 1.00 98.03 ? 56 PHE P CD2 1 +ATOM 28984 C CE1 . PHE P 1 56 ? 30.124 40.059 40.685 1.00 118.28 ? 56 PHE P CE1 1 +ATOM 28985 C CE2 . PHE P 1 56 ? 29.823 41.203 42.767 1.00 109.70 ? 56 PHE P CE2 1 +ATOM 28986 C CZ . PHE P 1 56 ? 30.658 40.593 41.838 1.00 114.15 ? 56 PHE P CZ 1 +ATOM 28987 N N . SER P 1 57 ? 23.961 42.903 39.812 1.00 99.56 ? 57 SER P N 1 +ATOM 28988 C CA . SER P 1 57 ? 22.504 42.954 39.755 1.00 88.59 ? 57 SER P CA 1 +ATOM 28989 C C . SER P 1 57 ? 22.077 42.672 38.314 1.00 87.69 ? 57 SER P C 1 +ATOM 28990 O O . SER P 1 57 ? 22.337 43.450 37.396 1.00 91.83 ? 57 SER P O 1 +ATOM 28991 C CB . SER P 1 57 ? 21.974 44.301 40.258 1.00 104.15 ? 57 SER P CB 1 +ATOM 28992 O OG . SER P 1 57 ? 22.070 44.374 41.666 1.00 129.33 ? 57 SER P OG 1 +ATOM 28993 N N . THR P 1 58 ? 21.389 41.561 38.124 1.00 90.12 ? 58 THR P N 1 +ATOM 28994 C CA . THR P 1 58 ? 20.870 41.216 36.823 1.00 110.75 ? 58 THR P CA 1 +ATOM 28995 C C . THR P 1 58 ? 19.759 42.150 36.406 1.00 140.85 ? 58 THR P C 1 +ATOM 28996 O O . THR P 1 58 ? 18.989 42.672 37.215 1.00 222.63 ? 58 THR P O 1 +ATOM 28997 C CB . THR P 1 58 ? 20.296 39.806 36.836 1.00 131.39 ? 58 THR P CB 1 +ATOM 28998 O OG1 . THR P 1 58 ? 19.215 39.729 37.775 1.00 135.19 ? 58 THR P OG1 1 +ATOM 28999 C CG2 . THR P 1 58 ? 21.355 38.852 37.267 1.00 153.92 ? 58 THR P CG2 1 +ATOM 29000 N N . ALA P 1 59 ? 19.602 42.319 35.123 1.00 138.48 ? 59 ALA P N 1 +ATOM 29001 C CA . ALA P 1 59 ? 18.568 43.228 34.697 1.00 112.01 ? 59 ALA P CA 1 +ATOM 29002 C C . ALA P 1 59 ? 17.178 42.605 34.833 1.00 87.04 ? 59 ALA P C 1 +ATOM 29003 O O . ALA P 1 59 ? 16.176 43.301 34.842 1.00 57.33 ? 59 ALA P O 1 +ATOM 29004 C CB . ALA P 1 59 ? 18.828 43.649 33.283 1.00 119.32 ? 59 ALA P CB 1 +ATOM 29005 N N . VAL P 1 60 ? 17.131 41.279 34.924 1.00 84.08 ? 60 VAL P N 1 +ATOM 29006 C CA . VAL P 1 60 ? 15.875 40.548 34.884 1.00 76.19 ? 60 VAL P CA 1 +ATOM 29007 C C . VAL P 1 60 ? 15.897 39.531 36.017 1.00 99.43 ? 60 VAL P C 1 +ATOM 29008 O O . VAL P 1 60 ? 16.927 38.883 36.270 1.00 132.12 ? 60 VAL P O 1 +ATOM 29009 C CB . VAL P 1 60 ? 15.739 39.806 33.546 1.00 82.09 ? 60 VAL P CB 1 +ATOM 29010 C CG1 . VAL P 1 60 ? 14.455 38.979 33.473 1.00 70.09 ? 60 VAL P CG1 1 +ATOM 29011 C CG2 . VAL P 1 60 ? 15.816 40.790 32.389 1.00 94.90 ? 60 VAL P CG2 1 +ATOM 29012 N N . PRO P 1 61 ? 14.758 39.349 36.699 1.00 96.32 ? 61 PRO P N 1 +ATOM 29013 C CA . PRO P 1 61 ? 14.723 38.345 37.786 1.00 97.56 ? 61 PRO P CA 1 +ATOM 29014 C C . PRO P 1 61 ? 14.890 36.903 37.312 1.00 85.61 ? 61 PRO P C 1 +ATOM 29015 O O . PRO P 1 61 ? 14.486 36.566 36.183 1.00 56.59 ? 61 PRO P O 1 +ATOM 29016 C CB . PRO P 1 61 ? 13.336 38.514 38.385 1.00 112.92 ? 61 PRO P CB 1 +ATOM 29017 C CG . PRO P 1 61 ? 12.537 39.156 37.297 1.00 140.94 ? 61 PRO P CG 1 +ATOM 29018 C CD . PRO P 1 61 ? 13.486 40.064 36.567 1.00 102.97 ? 61 PRO P CD 1 +ATOM 29019 N N . GLN P 1 62 ? 15.582 36.100 38.126 1.00 96.37 ? 62 GLN P N 1 +ATOM 29020 C CA . GLN P 1 62 ? 16.023 34.749 37.715 1.00 105.88 ? 62 GLN P CA 1 +ATOM 29021 C C . GLN P 1 62 ? 14.929 33.774 38.029 1.00 126.42 ? 62 GLN P C 1 +ATOM 29022 O O . GLN P 1 62 ? 15.206 32.652 38.421 1.00 165.29 ? 62 GLN P O 1 +ATOM 29023 C CB . GLN P 1 62 ? 17.328 34.323 38.430 1.00 74.52 ? 62 GLN P CB 1 +ATOM 29024 C CG . GLN P 1 62 ? 18.468 35.337 38.329 1.00 66.04 ? 62 GLN P CG 1 +ATOM 29025 C CD . GLN P 1 62 ? 18.867 35.617 36.894 1.00 71.68 ? 62 GLN P CD 1 +ATOM 29026 O OE1 . GLN P 1 62 ? 19.506 34.812 36.261 1.00 48.75 ? 62 GLN P OE1 1 +ATOM 29027 N NE2 . GLN P 1 62 ? 18.406 36.741 36.358 1.00 93.49 ? 62 GLN P NE2 1 +ATOM 29028 N N . SER P 1 63 ? 13.681 34.222 37.904 1.00 115.62 ? 63 SER P N 1 +ATOM 29029 C CA . SER P 1 63 ? 12.568 33.547 38.554 1.00 139.01 ? 63 SER P CA 1 +ATOM 29030 C C . SER P 1 63 ? 11.529 33.059 37.544 1.00 128.04 ? 63 SER P C 1 +ATOM 29031 O O . SER P 1 63 ? 10.425 32.636 37.923 1.00 184.71 ? 63 SER P O 1 +ATOM 29032 C CB . SER P 1 63 ? 11.942 34.475 39.616 1.00 144.47 ? 63 SER P CB 1 +ATOM 29033 O OG . SER P 1 63 ? 11.398 35.666 39.061 1.00 131.44 ? 63 SER P OG 1 +ATOM 29034 N N . ALA P 1 64 ? 11.892 33.107 36.269 1.00 90.75 ? 64 ALA P N 1 +ATOM 29035 C CA . ALA P 1 64 ? 10.931 32.898 35.194 1.00 107.26 ? 64 ALA P CA 1 +ATOM 29036 C C . ALA P 1 64 ? 10.270 31.526 35.280 1.00 102.84 ? 64 ALA P C 1 +ATOM 29037 O O . ALA P 1 64 ? 9.066 31.364 35.000 1.00 73.67 ? 64 ALA P O 1 +ATOM 29038 C CB . ALA P 1 64 ? 11.641 33.077 33.872 1.00 116.20 ? 64 ALA P CB 1 +ATOM 29039 N N . THR P 1 65 ? 11.067 30.538 35.688 1.00 99.50 ? 65 THR P N 1 +ATOM 29040 C CA . THR P 1 65 ? 10.605 29.145 35.812 1.00 81.54 ? 65 THR P CA 1 +ATOM 29041 C C . THR P 1 65 ? 9.359 29.003 36.675 1.00 86.74 ? 65 THR P C 1 +ATOM 29042 O O . THR P 1 65 ? 8.364 28.417 36.265 1.00 123.87 ? 65 THR P O 1 +ATOM 29043 C CB . THR P 1 65 ? 11.673 28.314 36.468 1.00 76.92 ? 65 THR P CB 1 +ATOM 29044 O OG1 . THR P 1 65 ? 12.953 28.741 35.978 1.00 88.38 ? 65 THR P OG1 1 +ATOM 29045 C CG2 . THR P 1 65 ? 11.434 26.835 36.202 1.00 70.23 ? 65 THR P CG2 1 +ATOM 29046 N N . ALA P 1 66 ? 9.387 29.643 37.837 1.00 114.87 ? 66 ALA P N 1 +ATOM 29047 C CA . ALA P 1 66 ? 8.284 29.549 38.778 1.00 94.30 ? 66 ALA P CA 1 +ATOM 29048 C C . ALA P 1 66 ? 7.072 30.335 38.274 1.00 72.14 ? 66 ALA P C 1 +ATOM 29049 O O . ALA P 1 66 ? 5.927 29.914 38.467 1.00 71.65 ? 66 ALA P O 1 +ATOM 29050 C CB . ALA P 1 66 ? 8.722 30.038 40.145 1.00 89.01 ? 66 ALA P CB 1 +ATOM 29051 N N . MET P 1 67 ? 7.340 31.425 37.572 1.00 56.78 ? 67 MET P N 1 +ATOM 29052 C CA . MET P 1 67 ? 6.276 32.193 37.005 1.00 73.16 ? 67 MET P CA 1 +ATOM 29053 C C . MET P 1 67 ? 5.532 31.330 35.988 1.00 74.96 ? 67 MET P C 1 +ATOM 29054 O O . MET P 1 67 ? 4.282 31.443 35.840 1.00 112.01 ? 67 MET P O 1 +ATOM 29055 C CB . MET P 1 67 ? 6.816 33.495 36.349 1.00 72.92 ? 67 MET P CB 1 +ATOM 29056 C CG . MET P 1 67 ? 7.310 34.562 37.321 1.00 73.10 ? 67 MET P CG 1 +ATOM 29057 S SD . MET P 1 67 ? 8.215 35.887 36.470 1.00 41.20 ? 67 MET P SD 1 +ATOM 29058 C CE . MET P 1 67 ? 8.514 37.027 37.819 1.00 60.12 ? 67 MET P CE 1 +ATOM 29059 N N . LEU P 1 68 ? 6.302 30.620 35.167 1.00 61.31 ? 68 LEU P N 1 +ATOM 29060 C CA . LEU P 1 68 ? 5.706 29.861 34.085 1.00 75.43 ? 68 LEU P CA 1 +ATOM 29061 C C . LEU P 1 68 ? 4.875 28.748 34.653 1.00 82.11 ? 68 LEU P C 1 +ATOM 29062 O O . LEU P 1 68 ? 3.745 28.523 34.196 1.00 164.89 ? 68 LEU P O 1 +ATOM 29063 C CB . LEU P 1 68 ? 6.755 29.257 33.172 1.00 81.53 ? 68 LEU P CB 1 +ATOM 29064 C CG . LEU P 1 68 ? 6.178 28.213 32.196 1.00 103.03 ? 68 LEU P CG 1 +ATOM 29065 C CD1 . LEU P 1 68 ? 5.227 28.860 31.168 1.00 101.08 ? 68 LEU P CD1 1 +ATOM 29066 C CD2 . LEU P 1 68 ? 7.278 27.451 31.477 1.00 106.48 ? 68 LEU P CD2 1 +ATOM 29067 N N . VAL P 1 69 ? 5.396 28.074 35.660 1.00 77.53 ? 69 VAL P N 1 +ATOM 29068 C CA . VAL P 1 69 ? 4.641 27.012 36.321 1.00 100.59 ? 69 VAL P CA 1 +ATOM 29069 C C . VAL P 1 69 ? 3.318 27.569 36.873 1.00 105.23 ? 69 VAL P C 1 +ATOM 29070 O O . VAL P 1 69 ? 2.255 26.952 36.737 1.00 93.25 ? 69 VAL P O 1 +ATOM 29071 C CB . VAL P 1 69 ? 5.439 26.341 37.485 1.00 98.61 ? 69 VAL P CB 1 +ATOM 29072 C CG1 . VAL P 1 69 ? 4.555 25.358 38.236 1.00 82.43 ? 69 VAL P CG1 1 +ATOM 29073 C CG2 . VAL P 1 69 ? 6.671 25.620 36.961 1.00 105.73 ? 69 VAL P CG2 1 +ATOM 29074 N N . THR P 1 70 ? 3.399 28.734 37.506 1.00 100.82 ? 70 THR P N 1 +ATOM 29075 C CA . THR P 1 70 ? 2.229 29.362 38.107 1.00 110.73 ? 70 THR P CA 1 +ATOM 29076 C C . THR P 1 70 ? 1.205 29.702 37.033 1.00 102.35 ? 70 THR P C 1 +ATOM 29077 O O . THR P 1 70 ? 0.004 29.474 37.197 1.00 100.55 ? 70 THR P O 1 +ATOM 29078 C CB . THR P 1 70 ? 2.632 30.620 38.912 1.00 108.11 ? 70 THR P CB 1 +ATOM 29079 O OG1 . THR P 1 70 ? 3.618 30.240 39.882 1.00 155.59 ? 70 THR P OG1 1 +ATOM 29080 C CG2 . THR P 1 70 ? 1.420 31.239 39.616 1.00 87.41 ? 70 THR P CG2 1 +ATOM 29081 N N . ALA P 1 71 ? 1.681 30.286 35.943 1.00 94.67 ? 71 ALA P N 1 +ATOM 29082 C CA . ALA P 1 71 ? 0.795 30.646 34.848 1.00 102.35 ? 71 ALA P CA 1 +ATOM 29083 C C . ALA P 1 71 ? 0.112 29.389 34.300 1.00 87.89 ? 71 ALA P C 1 +ATOM 29084 O O . ALA P 1 71 ? -1.073 29.401 33.945 1.00 85.19 ? 71 ALA P O 1 +ATOM 29085 C CB . ALA P 1 71 ? 1.575 31.401 33.753 1.00 89.72 ? 71 ALA P CB 1 +ATOM 29086 N N . LEU P 1 72 ? 0.893 28.329 34.141 1.00 89.29 ? 72 LEU P N 1 +ATOM 29087 C CA . LEU P 1 72 ? 0.368 27.077 33.605 1.00 93.74 ? 72 LEU P CA 1 +ATOM 29088 C C . LEU P 1 72 ? -0.719 26.541 34.520 1.00 101.77 ? 72 LEU P C 1 +ATOM 29089 O O . LEU P 1 72 ? -1.589 25.784 34.070 1.00 87.56 ? 72 LEU P O 1 +ATOM 29090 C CB . LEU P 1 72 ? 1.482 26.036 33.442 1.00 103.87 ? 72 LEU P CB 1 +ATOM 29091 C CG . LEU P 1 72 ? 2.504 26.331 32.330 1.00 84.13 ? 72 LEU P CG 1 +ATOM 29092 C CD1 . LEU P 1 72 ? 3.737 25.478 32.594 1.00 112.70 ? 72 LEU P CD1 1 +ATOM 29093 C CD2 . LEU P 1 72 ? 1.956 26.063 30.953 1.00 53.94 ? 72 LEU P CD2 1 +ATOM 29094 N N . LYS P 1 73 ? -0.657 26.897 35.803 1.00 105.44 ? 73 LYS P N 1 +ATOM 29095 C CA . LYS P 1 73 ? -1.647 26.399 36.755 1.00 110.52 ? 73 LYS P CA 1 +ATOM 29096 C C . LYS P 1 73 ? -2.871 27.263 36.725 1.00 84.93 ? 73 LYS P C 1 +ATOM 29097 O O . LYS P 1 73 ? -3.994 26.745 36.730 1.00 92.83 ? 73 LYS P O 1 +ATOM 29098 C CB . LYS P 1 73 ? -1.087 26.338 38.175 1.00 128.52 ? 73 LYS P CB 1 +ATOM 29099 C CG . LYS P 1 73 ? -1.966 25.570 39.171 1.00 137.12 ? 73 LYS P CG 1 +ATOM 29100 C CD . LYS P 1 73 ? -1.338 25.538 40.578 1.00 126.15 ? 73 LYS P CD 1 +ATOM 29101 C CE . LYS P 1 73 ? -2.379 25.419 41.676 1.00 126.92 ? 73 LYS P CE 1 +ATOM 29102 N NZ . LYS P 1 73 ? -2.283 24.134 42.417 1.00 109.49 ? 73 LYS P NZ 1 +ATOM 29103 N N . ASP P 1 74 ? -2.657 28.574 36.728 1.00 76.82 ? 74 ASP P N 1 +ATOM 29104 C CA . ASP P 1 74 ? -3.770 29.515 36.786 1.00 108.79 ? 74 ASP P CA 1 +ATOM 29105 C C . ASP P 1 74 ? -4.720 29.366 35.580 1.00 96.70 ? 74 ASP P C 1 +ATOM 29106 O O . ASP P 1 74 ? -5.926 29.635 35.693 1.00 72.56 ? 74 ASP P O 1 +ATOM 29107 C CB . ASP P 1 74 ? -3.260 30.963 36.869 1.00 105.25 ? 74 ASP P CB 1 +ATOM 29108 C CG . ASP P 1 74 ? -2.597 31.290 38.206 1.00 113.70 ? 74 ASP P CG 1 +ATOM 29109 O OD1 . ASP P 1 74 ? -2.936 30.669 39.259 1.00 130.21 ? 74 ASP P OD1 1 +ATOM 29110 O OD2 . ASP P 1 74 ? -1.713 32.171 38.198 1.00 94.70 ? 74 ASP P OD2 1 +ATOM 29111 N N . SER P 1 75 ? -4.178 28.913 34.456 1.00 84.70 ? 75 SER P N 1 +ATOM 29112 C CA . SER P 1 75 ? -4.949 28.774 33.217 1.00 72.12 ? 75 SER P CA 1 +ATOM 29113 C C . SER P 1 75 ? -6.057 27.733 33.340 1.00 80.35 ? 75 SER P C 1 +ATOM 29114 O O . SER P 1 75 ? -7.030 27.778 32.583 1.00 113.97 ? 75 SER P O 1 +ATOM 29115 C CB . SER P 1 75 ? -4.024 28.394 32.048 1.00 65.59 ? 75 SER P CB 1 +ATOM 29116 O OG . SER P 1 75 ? -3.815 26.991 31.991 1.00 49.79 ? 75 SER P OG 1 +ATOM 29117 N N . ARG P 1 76 ? -5.872 26.769 34.243 1.00 86.11 ? 76 ARG P N 1 +ATOM 29118 C CA . ARG P 1 76 ? -6.799 25.646 34.447 1.00 98.41 ? 76 ARG P CA 1 +ATOM 29119 C C . ARG P 1 76 ? -6.881 24.783 33.216 1.00 108.71 ? 76 ARG P C 1 +ATOM 29120 O O . ARG P 1 76 ? -7.936 24.261 32.860 1.00 104.38 ? 76 ARG P O 1 +ATOM 29121 C CB . ARG P 1 76 ? -8.183 26.135 34.840 1.00 112.68 ? 76 ARG P CB 1 +ATOM 29122 C CG . ARG P 1 76 ? -8.228 26.915 36.147 1.00 136.17 ? 76 ARG P CG 1 +ATOM 29123 C CD . ARG P 1 76 ? -9.659 27.327 36.468 1.00 168.86 ? 76 ARG P CD 1 +ATOM 29124 N NE . ARG P 1 76 ? -10.144 28.347 35.528 1.00 240.47 ? 76 ARG P NE 1 +ATOM 29125 C CZ . ARG P 1 76 ? -10.837 28.106 34.412 1.00 253.51 ? 76 ARG P CZ 1 +ATOM 29126 N NH1 . ARG P 1 76 ? -11.161 26.865 34.057 1.00 256.41 ? 76 ARG P NH1 1 +ATOM 29127 N NH2 . ARG P 1 76 ? -11.206 29.120 33.641 1.00 242.15 ? 76 ARG P NH2 1 +ATOM 29128 N N . TRP P 1 77 ? -5.742 24.662 32.549 1.00 125.80 ? 77 TRP P N 1 +ATOM 29129 C CA . TRP P 1 77 ? -5.576 23.717 31.450 1.00 137.47 ? 77 TRP P CA 1 +ATOM 29130 C C . TRP P 1 77 ? -4.584 22.611 31.845 1.00 132.44 ? 77 TRP P C 1 +ATOM 29131 O O . TRP P 1 77 ? -4.686 21.469 31.390 1.00 128.64 ? 77 TRP P O 1 +ATOM 29132 C CB . TRP P 1 77 ? -5.081 24.462 30.201 1.00 118.22 ? 77 TRP P CB 1 +ATOM 29133 C CG . TRP P 1 77 ? -6.162 24.912 29.312 1.00 115.89 ? 77 TRP P CG 1 +ATOM 29134 C CD1 . TRP P 1 77 ? -6.998 25.958 29.517 1.00 138.58 ? 77 TRP P CD1 1 +ATOM 29135 C CD2 . TRP P 1 77 ? -6.538 24.338 28.062 1.00 124.78 ? 77 TRP P CD2 1 +ATOM 29136 N NE1 . TRP P 1 77 ? -7.865 26.085 28.465 1.00 148.94 ? 77 TRP P NE1 1 +ATOM 29137 C CE2 . TRP P 1 77 ? -7.606 25.096 27.557 1.00 132.62 ? 77 TRP P CE2 1 +ATOM 29138 C CE3 . TRP P 1 77 ? -6.072 23.263 27.313 1.00 155.09 ? 77 TRP P CE3 1 +ATOM 29139 C CZ2 . TRP P 1 77 ? -8.225 24.807 26.338 1.00 133.77 ? 77 TRP P CZ2 1 +ATOM 29140 C CZ3 . TRP P 1 77 ? -6.689 22.979 26.098 1.00 166.06 ? 77 TRP P CZ3 1 +ATOM 29141 C CH2 . TRP P 1 77 ? -7.752 23.751 25.624 1.00 132.38 ? 77 TRP P CH2 1 +ATOM 29142 N N . PHE P 1 78 ? -3.595 22.981 32.658 1.00 121.35 ? 78 PHE P N 1 +ATOM 29143 C CA . PHE P 1 78 ? -2.458 22.122 32.972 1.00 91.24 ? 78 PHE P CA 1 +ATOM 29144 C C . PHE P 1 78 ? -2.355 21.870 34.479 1.00 90.74 ? 78 PHE P C 1 +ATOM 29145 O O . PHE P 1 78 ? -2.541 22.787 35.291 1.00 120.46 ? 78 PHE P O 1 +ATOM 29146 C CB . PHE P 1 78 ? -1.147 22.785 32.513 1.00 86.03 ? 78 PHE P CB 1 +ATOM 29147 C CG . PHE P 1 78 ? -1.110 23.150 31.054 1.00 70.93 ? 78 PHE P CG 1 +ATOM 29148 C CD1 . PHE P 1 78 ? -0.926 22.183 30.087 1.00 75.75 ? 78 PHE P CD1 1 +ATOM 29149 C CD2 . PHE P 1 78 ? -1.152 24.475 30.677 1.00 74.58 ? 78 PHE P CD2 1 +ATOM 29150 C CE1 . PHE P 1 78 ? -0.903 22.519 28.755 1.00 97.17 ? 78 PHE P CE1 1 +ATOM 29151 C CE2 . PHE P 1 78 ? -1.125 24.825 29.348 1.00 95.39 ? 78 PHE P CE2 1 +ATOM 29152 C CZ . PHE P 1 78 ? -0.988 23.848 28.383 1.00 107.87 ? 78 PHE P CZ 1 +ATOM 29153 N N . ILE P 1 79 ? -1.966 20.652 34.828 1.00 83.41 ? 79 ILE P N 1 +ATOM 29154 C CA . ILE P 1 79 ? -1.434 20.327 36.142 1.00 100.68 ? 79 ILE P CA 1 +ATOM 29155 C C . ILE P 1 79 ? 0.087 20.339 36.037 1.00 99.04 ? 79 ILE P C 1 +ATOM 29156 O O . ILE P 1 79 ? 0.660 19.665 35.169 1.00 106.82 ? 79 ILE P O 1 +ATOM 29157 C CB . ILE P 1 79 ? -1.852 18.915 36.566 1.00 131.67 ? 79 ILE P CB 1 +ATOM 29158 C CG1 . ILE P 1 79 ? -3.348 18.709 36.350 1.00 146.25 ? 79 ILE P CG1 1 +ATOM 29159 C CG2 . ILE P 1 79 ? -1.491 18.660 38.025 1.00 149.22 ? 79 ILE P CG2 1 +ATOM 29160 C CD1 . ILE P 1 79 ? -3.745 17.254 36.201 1.00 154.93 ? 79 ILE P CD1 1 +ATOM 29161 N N . PRO P 1 80 ? 0.745 21.169 36.855 1.00 94.99 ? 80 PRO P N 1 +ATOM 29162 C CA . PRO P 1 80 ? 2.174 21.134 36.758 1.00 82.05 ? 80 PRO P CA 1 +ATOM 29163 C C . PRO P 1 80 ? 2.711 20.091 37.710 1.00 63.76 ? 80 PRO P C 1 +ATOM 29164 O O . PRO P 1 80 ? 2.310 20.053 38.862 1.00 56.85 ? 80 PRO P O 1 +ATOM 29165 C CB . PRO P 1 80 ? 2.590 22.556 37.157 1.00 76.41 ? 80 PRO P CB 1 +ATOM 29166 C CG . PRO P 1 80 ? 1.405 23.381 36.867 1.00 75.10 ? 80 PRO P CG 1 +ATOM 29167 C CD . PRO P 1 80 ? 0.286 22.485 37.313 1.00 100.56 ? 80 PRO P CD 1 +ATOM 29168 N N . LEU P 1 81 ? 3.644 19.290 37.218 1.00 46.31 ? 81 LEU P N 1 +ATOM 29169 C CA . LEU P 1 81 ? 4.384 18.424 38.056 1.00 37.69 ? 81 LEU P CA 1 +ATOM 29170 C C . LEU P 1 81 ? 5.651 19.148 38.482 1.00 35.63 ? 81 LEU P C 1 +ATOM 29171 O O . LEU P 1 81 ? 6.301 19.871 37.709 1.00 25.49 ? 81 LEU P O 1 +ATOM 29172 C CB . LEU P 1 81 ? 4.657 17.162 37.305 1.00 46.28 ? 81 LEU P CB 1 +ATOM 29173 C CG . LEU P 1 81 ? 3.367 16.561 36.773 1.00 69.06 ? 81 LEU P CG 1 +ATOM 29174 C CD1 . LEU P 1 81 ? 3.691 15.359 35.896 1.00 79.02 ? 81 LEU P CD1 1 +ATOM 29175 C CD2 . LEU P 1 81 ? 2.454 16.147 37.908 1.00 72.06 ? 81 LEU P CD2 1 +ATOM 29176 N N . GLU P 1 82 ? 5.996 18.926 39.740 1.00 49.04 ? 82 GLU P N 1 +ATOM 29177 C CA . GLU P 1 82 ? 7.191 19.539 40.369 1.00 61.62 ? 82 GLU P CA 1 +ATOM 29178 C C . GLU P 1 82 ? 8.468 18.828 39.885 1.00 77.26 ? 82 GLU P C 1 +ATOM 29179 O O . GLU P 1 82 ? 8.783 17.687 40.329 1.00 100.28 ? 82 GLU P O 1 +ATOM 29180 C CB . GLU P 1 82 ? 7.109 19.539 41.941 1.00 50.94 ? 82 GLU P CB 1 +ATOM 29181 C CG . GLU P 1 82 ? 8.301 20.127 42.669 1.00 40.76 ? 82 GLU P CG 1 +ATOM 29182 C CD . GLU P 1 82 ? 8.481 21.646 42.485 1.00 62.17 ? 82 GLU P CD 1 +ATOM 29183 O OE1 . GLU P 1 82 ? 8.373 22.214 41.344 1.00 90.83 ? 82 GLU P OE1 1 +ATOM 29184 O OE2 . GLU P 1 82 ? 8.680 22.347 43.502 1.00 88.12 ? 82 GLU P OE2 1 +ATOM 29185 N N . ARG P 1 83 ? 9.219 19.543 39.044 1.00 58.04 ? 83 ARG P N 1 +ATOM 29186 C CA . ARG P 1 83 ? 10.553 19.147 38.685 1.00 57.50 ? 83 ARG P CA 1 +ATOM 29187 C C . ARG P 1 83 ? 11.665 20.166 39.093 1.00 92.28 ? 83 ARG P C 1 +ATOM 29188 O O . ARG P 1 83 ? 12.849 19.799 39.147 1.00 129.38 ? 83 ARG P O 1 +ATOM 29189 C CB . ARG P 1 83 ? 10.577 18.880 37.204 1.00 43.18 ? 83 ARG P CB 1 +ATOM 29190 C CG . ARG P 1 83 ? 9.552 17.886 36.771 1.00 44.78 ? 83 ARG P CG 1 +ATOM 29191 C CD . ARG P 1 83 ? 9.845 16.490 37.245 1.00 63.77 ? 83 ARG P CD 1 +ATOM 29192 N NE . ARG P 1 83 ? 8.902 15.590 36.540 1.00 81.54 ? 83 ARG P NE 1 +ATOM 29193 C CZ . ARG P 1 83 ? 7.824 14.997 37.079 1.00 72.27 ? 83 ARG P CZ 1 +ATOM 29194 N NH1 . ARG P 1 83 ? 7.530 15.180 38.381 1.00 74.43 ? 83 ARG P NH1 1 +ATOM 29195 N NH2 . ARG P 1 83 ? 7.070 14.200 36.312 1.00 49.19 ? 83 ARG P NH2 1 +ATOM 29196 N N . GLN P 1 84 ? 11.317 21.426 39.379 1.00 117.37 ? 84 GLN P N 1 +ATOM 29197 C CA . GLN P 1 84 ? 12.353 22.434 39.736 1.00 105.93 ? 84 GLN P CA 1 +ATOM 29198 C C . GLN P 1 84 ? 13.067 22.059 41.019 1.00 70.50 ? 84 GLN P C 1 +ATOM 29199 O O . GLN P 1 84 ? 14.279 22.030 41.052 1.00 81.77 ? 84 GLN P O 1 +ATOM 29200 C CB . GLN P 1 84 ? 11.793 23.852 39.874 1.00 129.18 ? 84 GLN P CB 1 +ATOM 29201 C CG . GLN P 1 84 ? 12.790 24.968 39.504 1.00 127.32 ? 84 GLN P CG 1 +ATOM 29202 C CD . GLN P 1 84 ? 12.243 26.377 39.718 1.00 139.57 ? 84 GLN P CD 1 +ATOM 29203 O OE1 . GLN P 1 84 ? 11.035 26.602 39.598 1.00 194.57 ? 84 GLN P OE1 1 +ATOM 29204 N NE2 . GLN P 1 84 ? 13.109 27.308 40.117 1.00 100.23 ? 84 GLN P NE2 1 +ATOM 29205 N N . GLY P 1 85 ? 12.343 21.534 41.968 1.00 59.25 ? 85 GLY P N 1 +ATOM 29206 C CA . GLY P 1 85 ? 13.034 20.902 43.078 1.00 93.52 ? 85 GLY P CA 1 +ATOM 29207 C C . GLY P 1 85 ? 13.027 19.357 43.174 1.00 96.70 ? 85 GLY P C 1 +ATOM 29208 O O . GLY P 1 85 ? 12.800 18.805 44.279 1.00 79.85 ? 85 GLY P O 1 +ATOM 29209 N N . LEU P 1 86 ? 13.241 18.656 42.058 1.00 59.67 ? 86 LEU P N 1 +ATOM 29210 C CA . LEU P 1 86 ? 12.922 17.232 42.009 1.00 64.16 ? 86 LEU P CA 1 +ATOM 29211 C C . LEU P 1 86 ? 13.741 16.472 43.030 1.00 86.61 ? 86 LEU P C 1 +ATOM 29212 O O . LEU P 1 86 ? 13.299 15.447 43.592 1.00 126.44 ? 86 LEU P O 1 +ATOM 29213 C CB . LEU P 1 86 ? 13.186 16.676 40.616 1.00 87.66 ? 86 LEU P CB 1 +ATOM 29214 C CG . LEU P 1 86 ? 13.140 15.145 40.343 1.00 100.28 ? 86 LEU P CG 1 +ATOM 29215 C CD1 . LEU P 1 86 ? 11.793 14.519 40.656 1.00 64.98 ? 86 LEU P CD1 1 +ATOM 29216 C CD2 . LEU P 1 86 ? 13.521 14.865 38.884 1.00 115.37 ? 86 LEU P CD2 1 +ATOM 29217 N N . GLN P 1 87 ? 14.966 16.939 43.257 1.00 106.06 ? 87 GLN P N 1 +ATOM 29218 C CA . GLN P 1 87 ? 15.900 16.216 44.132 1.00 117.51 ? 87 GLN P CA 1 +ATOM 29219 C C . GLN P 1 87 ? 15.350 16.084 45.579 1.00 119.64 ? 87 GLN P C 1 +ATOM 29220 O O . GLN P 1 87 ? 15.396 15.005 46.196 1.00 72.52 ? 87 GLN P O 1 +ATOM 29221 C CB . GLN P 1 87 ? 17.271 16.897 44.106 1.00 116.80 ? 87 GLN P CB 1 +ATOM 29222 C CG . GLN P 1 87 ? 18.441 15.928 44.236 1.00 127.87 ? 87 GLN P CG 1 +ATOM 29223 C CD . GLN P 1 87 ? 18.280 14.657 43.396 1.00 117.73 ? 87 GLN P CD 1 +ATOM 29224 O OE1 . GLN P 1 87 ? 18.130 14.720 42.173 1.00 102.50 ? 87 GLN P OE1 1 +ATOM 29225 N NE2 . GLN P 1 87 ? 18.338 13.496 44.053 1.00 95.38 ? 87 GLN P NE2 1 +ATOM 29226 N N . ASN P 1 88 ? 14.744 17.164 46.064 1.00 119.92 ? 88 ASN P N 1 +ATOM 29227 C CA . ASN P 1 88 ? 14.138 17.176 47.387 1.00 100.67 ? 88 ASN P CA 1 +ATOM 29228 C C . ASN P 1 88 ? 12.924 16.274 47.473 1.00 90.90 ? 88 ASN P C 1 +ATOM 29229 O O . ASN P 1 88 ? 12.687 15.630 48.517 1.00 100.53 ? 88 ASN P O 1 +ATOM 29230 C CB . ASN P 1 88 ? 13.693 18.584 47.725 1.00 86.85 ? 88 ASN P CB 1 +ATOM 29231 C CG . ASN P 1 88 ? 14.811 19.563 47.575 1.00 71.43 ? 88 ASN P CG 1 +ATOM 29232 O OD1 . ASN P 1 88 ? 15.943 19.274 48.026 1.00 110.39 ? 88 ASN P OD1 1 +ATOM 29233 N ND2 . ASN P 1 88 ? 14.508 20.749 47.080 1.00 45.75 ? 88 ASN P ND2 1 +ATOM 29234 N N . LEU P 1 89 ? 12.155 16.246 46.383 1.00 56.89 ? 89 LEU P N 1 +ATOM 29235 C CA . LEU P 1 89 ? 10.997 15.407 46.305 1.00 51.08 ? 89 LEU P CA 1 +ATOM 29236 C C . LEU P 1 89 ? 11.405 13.928 46.454 1.00 69.59 ? 89 LEU P C 1 +ATOM 29237 O O . LEU P 1 89 ? 10.821 13.139 47.234 1.00 88.75 ? 89 LEU P O 1 +ATOM 29238 C CB . LEU P 1 89 ? 10.338 15.648 44.976 1.00 54.12 ? 89 LEU P CB 1 +ATOM 29239 C CG . LEU P 1 89 ? 8.832 15.464 44.876 1.00 78.28 ? 89 LEU P CG 1 +ATOM 29240 C CD1 . LEU P 1 89 ? 8.472 14.331 43.948 1.00 75.10 ? 89 LEU P CD1 1 +ATOM 29241 C CD2 . LEU P 1 89 ? 8.178 15.234 46.235 1.00 93.07 ? 89 LEU P CD2 1 +ATOM 29242 N N . LEU P 1 90 ? 12.500 13.568 45.796 1.00 76.80 ? 90 LEU P N 1 +ATOM 29243 C CA . LEU P 1 90 ? 12.978 12.185 45.831 1.00 77.64 ? 90 LEU P CA 1 +ATOM 29244 C C . LEU P 1 90 ? 13.521 11.846 47.214 1.00 74.93 ? 90 LEU P C 1 +ATOM 29245 O O . LEU P 1 90 ? 13.505 10.675 47.647 1.00 73.86 ? 90 LEU P O 1 +ATOM 29246 C CB . LEU P 1 90 ? 14.045 11.968 44.757 1.00 77.46 ? 90 LEU P CB 1 +ATOM 29247 C CG . LEU P 1 90 ? 13.544 12.200 43.338 1.00 76.57 ? 90 LEU P CG 1 +ATOM 29248 C CD1 . LEU P 1 90 ? 14.732 12.434 42.408 1.00 94.84 ? 90 LEU P CD1 1 +ATOM 29249 C CD2 . LEU P 1 90 ? 12.692 11.011 42.891 1.00 73.58 ? 90 LEU P CD2 1 +ATOM 29250 N N . ASN P 1 91 ? 14.048 12.867 47.878 1.00 65.96 ? 91 ASN P N 1 +ATOM 29251 C CA . ASN P 1 91 ? 14.633 12.673 49.174 1.00 83.62 ? 91 ASN P CA 1 +ATOM 29252 C C . ASN P 1 91 ? 13.544 12.373 50.180 1.00 64.75 ? 91 ASN P C 1 +ATOM 29253 O O . ASN P 1 91 ? 13.677 11.460 51.002 1.00 76.38 ? 91 ASN P O 1 +ATOM 29254 C CB . ASN P 1 91 ? 15.470 13.895 49.577 1.00 99.32 ? 91 ASN P CB 1 +ATOM 29255 C CG . ASN P 1 91 ? 16.875 13.491 50.020 1.00 103.93 ? 91 ASN P CG 1 +ATOM 29256 O OD1 . ASN P 1 91 ? 17.537 12.738 49.298 1.00 53.71 ? 91 ASN P OD1 1 +ATOM 29257 N ND2 . ASN P 1 91 ? 17.230 13.786 51.287 1.00 113.99 ? 91 ASN P ND2 1 +ATOM 29258 N N . GLU P 1 92 ? 12.517 13.193 50.176 1.00 66.71 ? 92 GLU P N 1 +ATOM 29259 C CA . GLU P 1 92 ? 11.400 12.977 51.096 1.00 94.52 ? 92 GLU P CA 1 +ATOM 29260 C C . GLU P 1 92 ? 10.837 11.575 50.886 1.00 81.35 ? 92 GLU P C 1 +ATOM 29261 O O . GLU P 1 92 ? 10.370 10.939 51.840 1.00 105.69 ? 92 GLU P O 1 +ATOM 29262 C CB . GLU P 1 92 ? 10.293 14.054 50.922 1.00 100.41 ? 92 GLU P CB 1 +ATOM 29263 C CG . GLU P 1 92 ? 10.412 15.259 51.839 1.00 83.83 ? 92 GLU P CG 1 +ATOM 29264 C CD . GLU P 1 92 ? 10.547 14.879 53.318 1.00 91.50 ? 92 GLU P CD 1 +ATOM 29265 O OE1 . GLU P 1 92 ? 9.650 14.200 53.885 1.00 96.64 ? 92 GLU P OE1 1 +ATOM 29266 O OE2 . GLU P 1 92 ? 11.562 15.295 53.943 1.00 70.15 ? 92 GLU P OE2 1 +ATOM 29267 N N . ARG P 1 93 ? 10.812 11.133 49.635 1.00 59.54 ? 93 ARG P N 1 +ATOM 29268 C CA . ARG P 1 93 ? 10.276 9.827 49.333 1.00 74.03 ? 93 ARG P CA 1 +ATOM 29269 C C . ARG P 1 93 ? 11.206 8.719 49.853 1.00 97.30 ? 93 ARG P C 1 +ATOM 29270 O O . ARG P 1 93 ? 10.750 7.681 50.331 1.00 82.90 ? 93 ARG P O 1 +ATOM 29271 C CB . ARG P 1 93 ? 10.016 9.727 47.842 1.00 84.59 ? 93 ARG P CB 1 +ATOM 29272 C CG . ARG P 1 93 ? 8.849 10.607 47.413 1.00 84.01 ? 93 ARG P CG 1 +ATOM 29273 C CD . ARG P 1 93 ? 8.756 10.811 45.912 1.00 104.13 ? 93 ARG P CD 1 +ATOM 29274 N NE . ARG P 1 93 ? 7.750 9.956 45.291 1.00 131.26 ? 93 ARG P NE 1 +ATOM 29275 C CZ . ARG P 1 93 ? 7.997 8.780 44.709 1.00 133.13 ? 93 ARG P CZ 1 +ATOM 29276 N NH1 . ARG P 1 93 ? 9.228 8.280 44.620 1.00 96.83 ? 93 ARG P NH1 1 +ATOM 29277 N NH2 . ARG P 1 93 ? 6.987 8.127 44.161 1.00 167.00 ? 93 ARG P NH2 1 +ATOM 29278 N N . LYS P 1 94 ? 12.513 8.987 49.883 1.00 131.35 ? 94 LYS P N 1 +ATOM 29279 C CA . LYS P 1 94 ? 13.473 8.064 50.532 1.00 113.72 ? 94 LYS P CA 1 +ATOM 29280 C C . LYS P 1 94 ? 13.217 7.979 52.026 1.00 85.35 ? 94 LYS P C 1 +ATOM 29281 O O . LYS P 1 94 ? 13.215 6.872 52.596 1.00 97.47 ? 94 LYS P O 1 +ATOM 29282 C CB . LYS P 1 94 ? 14.911 8.531 50.342 1.00 118.18 ? 94 LYS P CB 1 +ATOM 29283 C CG . LYS P 1 94 ? 15.584 8.063 49.065 1.00 146.07 ? 94 LYS P CG 1 +ATOM 29284 C CD . LYS P 1 94 ? 16.926 8.762 48.902 1.00 162.29 ? 94 LYS P CD 1 +ATOM 29285 C CE . LYS P 1 94 ? 17.861 8.035 47.947 1.00 172.91 ? 94 LYS P CE 1 +ATOM 29286 N NZ . LYS P 1 94 ? 18.993 8.920 47.561 1.00 166.42 ? 94 LYS P NZ 1 +ATOM 29287 N N . ILE P 1 95 ? 12.944 9.133 52.645 1.00 54.68 ? 95 ILE P N 1 +ATOM 29288 C CA . ILE P 1 95 ? 12.708 9.153 54.071 1.00 52.86 ? 95 ILE P CA 1 +ATOM 29289 C C . ILE P 1 95 ? 11.414 8.425 54.438 1.00 62.91 ? 95 ILE P C 1 +ATOM 29290 O O . ILE P 1 95 ? 11.338 7.748 55.505 1.00 57.69 ? 95 ILE P O 1 +ATOM 29291 C CB . ILE P 1 95 ? 12.665 10.562 54.660 1.00 50.77 ? 95 ILE P CB 1 +ATOM 29292 C CG1 . ILE P 1 95 ? 13.827 11.377 54.154 1.00 54.92 ? 95 ILE P CG1 1 +ATOM 29293 C CG2 . ILE P 1 95 ? 12.768 10.466 56.174 1.00 51.04 ? 95 ILE P CG2 1 +ATOM 29294 C CD1 . ILE P 1 95 ? 14.066 12.672 54.911 1.00 67.01 ? 95 ILE P CD1 1 +ATOM 29295 N N . ILE P 1 96 ? 10.378 8.650 53.612 1.00 61.03 ? 96 ILE P N 1 +ATOM 29296 C CA . ILE P 1 96 ? 9.096 7.968 53.757 1.00 59.15 ? 96 ILE P CA 1 +ATOM 29297 C C . ILE P 1 96 ? 9.316 6.489 53.725 1.00 61.24 ? 96 ILE P C 1 +ATOM 29298 O O . ILE P 1 96 ? 8.982 5.787 54.678 1.00 59.75 ? 96 ILE P O 1 +ATOM 29299 C CB . ILE P 1 96 ? 8.107 8.336 52.653 1.00 68.11 ? 96 ILE P CB 1 +ATOM 29300 C CG1 . ILE P 1 96 ? 7.664 9.794 52.818 1.00 99.03 ? 96 ILE P CG1 1 +ATOM 29301 C CG2 . ILE P 1 96 ? 6.873 7.467 52.758 1.00 73.11 ? 96 ILE P CG2 1 +ATOM 29302 C CD1 . ILE P 1 96 ? 6.623 10.233 51.807 1.00 124.16 ? 96 ILE P CD1 1 +ATOM 29303 N N . ARG P 1 97 ? 9.888 6.011 52.628 1.00 83.75 ? 97 ARG P N 1 +ATOM 29304 C CA . ARG P 1 97 ? 10.094 4.565 52.445 1.00 100.38 ? 97 ARG P CA 1 +ATOM 29305 C C . ARG P 1 97 ? 10.946 3.947 53.565 1.00 94.98 ? 97 ARG P C 1 +ATOM 29306 O O . ARG P 1 97 ? 10.751 2.786 53.951 1.00 98.30 ? 97 ARG P O 1 +ATOM 29307 C CB . ARG P 1 97 ? 10.745 4.272 51.091 1.00 118.41 ? 97 ARG P CB 1 +ATOM 29308 C CG . ARG P 1 97 ? 9.790 3.767 50.020 1.00 124.23 ? 97 ARG P CG 1 +ATOM 29309 C CD . ARG P 1 97 ? 10.529 3.434 48.726 1.00 112.82 ? 97 ARG P CD 1 +ATOM 29310 N NE . ARG P 1 97 ? 10.787 4.624 47.912 1.00 98.17 ? 97 ARG P NE 1 +ATOM 29311 C CZ . ARG P 1 97 ? 10.062 5.000 46.857 1.00 80.08 ? 97 ARG P CZ 1 +ATOM 29312 N NH1 . ARG P 1 97 ? 9.024 4.286 46.443 1.00 60.78 ? 97 ARG P NH1 1 +ATOM 29313 N NH2 . ARG P 1 97 ? 10.378 6.116 46.219 1.00 105.23 ? 97 ARG P NH2 1 +ATOM 29314 N N . ALA P 1 98 ? 11.863 4.738 54.112 1.00 93.21 ? 98 ALA P N 1 +ATOM 29315 C CA . ALA P 1 98 ? 12.686 4.280 55.214 1.00 96.13 ? 98 ALA P CA 1 +ATOM 29316 C C . ALA P 1 98 ? 11.890 4.262 56.527 1.00 114.93 ? 98 ALA P C 1 +ATOM 29317 O O . ALA P 1 98 ? 12.172 3.450 57.417 1.00 109.29 ? 98 ALA P O 1 +ATOM 29318 C CB . ALA P 1 98 ? 13.909 5.165 55.342 1.00 87.92 ? 98 ALA P CB 1 +ATOM 29319 N N . ALA P 1 99 ? 10.893 5.148 56.626 1.00 106.79 ? 99 ALA P N 1 +ATOM 29320 C CA . ALA P 1 99 ? 10.022 5.233 57.809 1.00 84.89 ? 99 ALA P CA 1 +ATOM 29321 C C . ALA P 1 99 ? 9.125 4.019 57.958 1.00 96.44 ? 99 ALA P C 1 +ATOM 29322 O O . ALA P 1 99 ? 9.055 3.394 59.027 1.00 157.65 ? 99 ALA P O 1 +ATOM 29323 C CB . ALA P 1 99 ? 9.167 6.468 57.744 1.00 67.78 ? 99 ALA P CB 1 +ATOM 29324 N N . GLN P 1 100 ? 8.435 3.667 56.881 1.00 86.24 ? 100 GLN P N 1 +ATOM 29325 C CA . GLN P 1 100 ? 7.310 2.725 56.975 1.00 98.53 ? 100 GLN P CA 1 +ATOM 29326 C C . GLN P 1 100 ? 7.598 1.325 56.456 1.00 96.91 ? 100 GLN P C 1 +ATOM 29327 O O . GLN P 1 100 ? 6.696 0.492 56.376 1.00 121.40 ? 100 GLN P O 1 +ATOM 29328 C CB . GLN P 1 100 ? 6.065 3.305 56.282 1.00 94.04 ? 100 GLN P CB 1 +ATOM 29329 C CG . GLN P 1 100 ? 6.325 3.976 54.950 1.00 91.13 ? 100 GLN P CG 1 +ATOM 29330 C CD . GLN P 1 100 ? 5.321 5.076 54.627 1.00 86.55 ? 100 GLN P CD 1 +ATOM 29331 O OE1 . GLN P 1 100 ? 5.184 6.088 55.353 1.00 61.54 ? 100 GLN P OE1 1 +ATOM 29332 N NE2 . GLN P 1 100 ? 4.646 4.908 53.502 1.00 100.07 ? 100 GLN P NE2 1 +ATOM 29333 N N . GLU P 1 101 ? 8.851 1.059 56.120 1.00 93.88 ? 101 GLU P N 1 +ATOM 29334 C CA . GLU P 1 101 ? 9.209 -0.237 55.558 1.00 113.49 ? 101 GLU P CA 1 +ATOM 29335 C C . GLU P 1 101 ? 9.073 -1.374 56.575 1.00 114.46 ? 101 GLU P C 1 +ATOM 29336 O O . GLU P 1 101 ? 8.943 -2.546 56.192 1.00 100.33 ? 101 GLU P O 1 +ATOM 29337 C CB . GLU P 1 101 ? 10.629 -0.201 54.969 1.00 133.02 ? 101 GLU P CB 1 +ATOM 29338 C CG . GLU P 1 101 ? 11.703 0.331 55.912 1.00 115.18 ? 101 GLU P CG 1 +ATOM 29339 C CD . GLU P 1 101 ? 13.093 0.259 55.302 1.00 122.51 ? 101 GLU P CD 1 +ATOM 29340 O OE1 . GLU P 1 101 ? 13.196 0.120 54.063 1.00 113.67 ? 101 GLU P OE1 1 +ATOM 29341 O OE2 . GLU P 1 101 ? 14.092 0.340 56.060 1.00 188.50 ? 101 GLU P OE2 1 +ATOM 29342 N N . ASN P 1 102 ? 9.156 -1.047 57.862 1.00 106.52 ? 102 ASN P N 1 +ATOM 29343 C CA . ASN P 1 102 ? 9.138 -2.076 58.898 1.00 116.46 ? 102 ASN P CA 1 +ATOM 29344 C C . ASN P 1 102 ? 7.735 -2.356 59.411 1.00 138.06 ? 102 ASN P C 1 +ATOM 29345 O O . ASN P 1 102 ? 7.549 -3.220 60.269 1.00 149.14 ? 102 ASN P O 1 +ATOM 29346 C CB . ASN P 1 102 ? 10.036 -1.676 60.068 1.00 114.74 ? 102 ASN P CB 1 +ATOM 29347 C CG . ASN P 1 102 ? 11.512 -1.784 59.741 1.00 125.85 ? 102 ASN P CG 1 +ATOM 29348 O OD1 . ASN P 1 102 ? 12.085 -2.876 59.708 1.00 81.77 ? 102 ASN P OD1 1 +ATOM 29349 N ND2 . ASN P 1 102 ? 12.113 -0.648 59.416 1.00 169.16 ? 102 ASN P ND2 1 +ATOM 29350 N N . GLY P 1 103 ? 6.749 -1.613 58.915 1.00 138.83 ? 103 GLY P N 1 +ATOM 29351 C CA . GLY P 1 103 ? 5.369 -1.804 59.356 1.00 117.85 ? 103 GLY P CA 1 +ATOM 29352 C C . GLY P 1 103 ? 5.169 -1.583 60.846 1.00 97.54 ? 103 GLY P C 1 +ATOM 29353 O O . GLY P 1 103 ? 4.343 -2.239 61.484 1.00 92.82 ? 103 GLY P O 1 +ATOM 29354 N N . THR P 1 104 ? 5.923 -0.650 61.406 1.00 94.13 ? 104 THR P N 1 +ATOM 29355 C CA . THR P 1 104 ? 5.644 -0.178 62.741 1.00 107.81 ? 104 THR P CA 1 +ATOM 29356 C C . THR P 1 104 ? 4.897 1.149 62.666 1.00 122.72 ? 104 THR P C 1 +ATOM 29357 O O . THR P 1 104 ? 4.115 1.453 63.559 1.00 143.42 ? 104 THR P O 1 +ATOM 29358 C CB . THR P 1 104 ? 6.921 -0.022 63.593 1.00 117.60 ? 104 THR P CB 1 +ATOM 29359 O OG1 . THR P 1 104 ? 7.770 0.999 63.043 1.00 107.85 ? 104 THR P OG1 1 +ATOM 29360 C CG2 . THR P 1 104 ? 7.669 -1.346 63.666 1.00 112.00 ? 104 THR P CG2 1 +ATOM 29361 N N . VAL P 1 105 ? 5.069 1.905 61.582 1.00 131.46 ? 105 VAL P N 1 +ATOM 29362 C CA . VAL P 1 105 ? 4.523 3.272 61.528 1.00 143.61 ? 105 VAL P CA 1 +ATOM 29363 C C . VAL P 1 105 ? 3.006 3.256 61.662 1.00 139.29 ? 105 VAL P C 1 +ATOM 29364 O O . VAL P 1 105 ? 2.325 2.388 61.102 1.00 113.95 ? 105 VAL P O 1 +ATOM 29365 C CB . VAL P 1 105 ? 4.975 4.077 60.268 1.00 146.84 ? 105 VAL P CB 1 +ATOM 29366 C CG1 . VAL P 1 105 ? 3.902 5.056 59.788 1.00 98.50 ? 105 VAL P CG1 1 +ATOM 29367 C CG2 . VAL P 1 105 ? 6.280 4.846 60.556 1.00 179.15 ? 105 VAL P CG2 1 +ATOM 29368 N N . ALA P 1 106 ? 2.506 4.223 62.435 1.00 156.11 ? 106 ALA P N 1 +ATOM 29369 C CA . ALA P 1 106 ? 1.103 4.300 62.819 1.00 150.92 ? 106 ALA P CA 1 +ATOM 29370 C C . ALA P 1 106 ? 0.201 4.460 61.598 1.00 164.29 ? 106 ALA P C 1 +ATOM 29371 O O . ALA P 1 106 ? 0.479 5.271 60.709 1.00 213.26 ? 106 ALA P O 1 +ATOM 29372 C CB . ALA P 1 106 ? 0.894 5.457 63.784 1.00 145.47 ? 106 ALA P CB 1 +ATOM 29373 N N . ILE P 1 107 ? -0.876 3.677 61.561 1.00 145.74 ? 107 ILE P N 1 +ATOM 29374 C CA . ILE P 1 107 ? -1.756 3.600 60.390 1.00 135.01 ? 107 ILE P CA 1 +ATOM 29375 C C . ILE P 1 107 ? -2.371 4.967 60.008 1.00 128.12 ? 107 ILE P C 1 +ATOM 29376 O O . ILE P 1 107 ? -2.623 5.248 58.834 1.00 93.43 ? 107 ILE P O 1 +ATOM 29377 C CB . ILE P 1 107 ? -2.873 2.548 60.619 1.00 119.46 ? 107 ILE P CB 1 +ATOM 29378 C CG1 . ILE P 1 107 ? -3.615 2.235 59.311 1.00 112.49 ? 107 ILE P CG1 1 +ATOM 29379 C CG2 . ILE P 1 107 ? -3.849 3.022 61.693 1.00 105.97 ? 107 ILE P CG2 1 +ATOM 29380 C CD1 . ILE P 1 107 ? -2.734 1.739 58.183 1.00 112.99 ? 107 ILE P CD1 1 +ATOM 29381 N N . ASN P 1 108 ? -2.580 5.819 61.005 1.00 142.61 ? 108 ASN P N 1 +ATOM 29382 C CA . ASN P 1 108 ? -3.050 7.191 60.776 1.00 161.67 ? 108 ASN P CA 1 +ATOM 29383 C C . ASN P 1 108 ? -1.968 8.044 60.119 1.00 158.38 ? 108 ASN P C 1 +ATOM 29384 O O . ASN P 1 108 ? -2.252 8.935 59.324 1.00 158.62 ? 108 ASN P O 1 +ATOM 29385 C CB . ASN P 1 108 ? -3.457 7.847 62.103 1.00 181.72 ? 108 ASN P CB 1 +ATOM 29386 C CG . ASN P 1 108 ? -3.978 6.846 63.118 1.00 195.88 ? 108 ASN P CG 1 +ATOM 29387 O OD1 . ASN P 1 108 ? -5.164 6.518 63.126 1.00 240.89 ? 108 ASN P OD1 1 +ATOM 29388 N ND2 . ASN P 1 108 ? -3.091 6.352 63.980 1.00 185.14 ? 108 ASN P ND2 1 +ATOM 29389 N N . ASN P 1 109 ? -0.725 7.785 60.505 1.00 147.74 ? 109 ASN P N 1 +ATOM 29390 C CA . ASN P 1 109 ? 0.409 8.588 60.078 1.00 139.46 ? 109 ASN P CA 1 +ATOM 29391 C C . ASN P 1 109 ? 0.991 8.137 58.739 1.00 138.31 ? 109 ASN P C 1 +ATOM 29392 O O . ASN P 1 109 ? 1.749 8.875 58.107 1.00 147.24 ? 109 ASN P O 1 +ATOM 29393 C CB . ASN P 1 109 ? 1.493 8.547 61.155 1.00 139.18 ? 109 ASN P CB 1 +ATOM 29394 C CG . ASN P 1 109 ? 1.753 9.912 61.757 1.00 140.39 ? 109 ASN P CG 1 +ATOM 29395 O OD1 . ASN P 1 109 ? 2.839 10.473 61.603 1.00 167.65 ? 109 ASN P OD1 1 +ATOM 29396 N ND2 . ASN P 1 109 ? 0.752 10.465 62.426 1.00 127.59 ? 109 ASN P ND2 1 +ATOM 29397 N N . ARG P 1 110 ? 0.638 6.918 58.329 1.00 123.28 ? 110 ARG P N 1 +ATOM 29398 C CA . ARG P 1 110 ? 1.210 6.258 57.143 1.00 96.55 ? 110 ARG P CA 1 +ATOM 29399 C C . ARG P 1 110 ? 1.031 7.101 55.887 1.00 97.82 ? 110 ARG P C 1 +ATOM 29400 O O . ARG P 1 110 ? -0.047 7.660 55.657 1.00 134.05 ? 110 ARG P O 1 +ATOM 29401 C CB . ARG P 1 110 ? 0.516 4.908 56.932 1.00 90.49 ? 110 ARG P CB 1 +ATOM 29402 C CG . ARG P 1 110 ? 1.308 3.903 56.132 1.00 103.98 ? 110 ARG P CG 1 +ATOM 29403 C CD . ARG P 1 110 ? 1.064 2.482 56.610 1.00 119.18 ? 110 ARG P CD 1 +ATOM 29404 N NE . ARG P 1 110 ? -0.064 1.868 55.903 1.00 124.15 ? 110 ARG P NE 1 +ATOM 29405 C CZ . ARG P 1 110 ? 0.006 0.760 55.155 1.00 127.79 ? 110 ARG P CZ 1 +ATOM 29406 N NH1 . ARG P 1 110 ? 1.153 0.088 54.999 1.00 101.04 ? 110 ARG P NH1 1 +ATOM 29407 N NH2 . ARG P 1 110 ? -1.099 0.294 54.576 1.00 141.95 ? 110 ARG P NH2 1 +ATOM 29408 N N . ILE P 1 111 ? 2.087 7.234 55.088 1.00 91.88 ? 111 ILE P N 1 +ATOM 29409 C CA . ILE P 1 111 ? 1.979 7.942 53.809 1.00 93.31 ? 111 ILE P CA 1 +ATOM 29410 C C . ILE P 1 111 ? 2.057 6.960 52.665 1.00 96.48 ? 111 ILE P C 1 +ATOM 29411 O O . ILE P 1 111 ? 3.092 6.341 52.485 1.00 100.31 ? 111 ILE P O 1 +ATOM 29412 C CB . ILE P 1 111 ? 3.081 8.992 53.623 1.00 83.25 ? 111 ILE P CB 1 +ATOM 29413 C CG1 . ILE P 1 111 ? 2.931 10.086 54.683 1.00 108.43 ? 111 ILE P CG1 1 +ATOM 29414 C CG2 . ILE P 1 111 ? 2.991 9.609 52.234 1.00 77.72 ? 111 ILE P CG2 1 +ATOM 29415 C CD1 . ILE P 1 111 ? 4.119 11.025 54.799 1.00 110.97 ? 111 ILE P CD1 1 +ATOM 29416 N N . PRO P 1 112 ? 0.974 6.835 51.876 1.00 107.81 ? 112 PRO P N 1 +ATOM 29417 C CA . PRO P 1 112 ? 0.968 5.885 50.782 1.00 104.49 ? 112 PRO P CA 1 +ATOM 29418 C C . PRO P 1 112 ? 1.714 6.451 49.577 1.00 115.78 ? 112 PRO P C 1 +ATOM 29419 O O . PRO P 1 112 ? 1.453 7.587 49.150 1.00 97.74 ? 112 PRO P O 1 +ATOM 29420 C CB . PRO P 1 112 ? -0.520 5.718 50.479 1.00 102.83 ? 112 PRO P CB 1 +ATOM 29421 C CG . PRO P 1 112 ? -1.107 7.049 50.807 1.00 112.73 ? 112 PRO P CG 1 +ATOM 29422 C CD . PRO P 1 112 ? -0.241 7.673 51.875 1.00 116.44 ? 112 PRO P CD 1 +ATOM 29423 N N . LEU P 1 113 ? 2.650 5.665 49.051 1.00 130.53 ? 113 LEU P N 1 +ATOM 29424 C CA . LEU P 1 113 ? 3.531 6.127 47.987 1.00 108.62 ? 113 LEU P CA 1 +ATOM 29425 C C . LEU P 1 113 ? 3.173 5.525 46.651 1.00 96.09 ? 113 LEU P C 1 +ATOM 29426 O O . LEU P 1 113 ? 2.835 4.338 46.524 1.00 81.84 ? 113 LEU P O 1 +ATOM 29427 C CB . LEU P 1 113 ? 4.985 5.831 48.315 1.00 101.63 ? 113 LEU P CB 1 +ATOM 29428 C CG . LEU P 1 113 ? 5.686 6.890 49.158 1.00 107.05 ? 113 LEU P CG 1 +ATOM 29429 C CD1 . LEU P 1 113 ? 7.139 6.484 49.315 1.00 103.58 ? 113 LEU P CD1 1 +ATOM 29430 C CD2 . LEU P 1 113 ? 5.582 8.279 48.532 1.00 116.13 ? 113 LEU P CD2 1 +ATOM 29431 N N . GLN P 1 114 ? 3.273 6.375 45.645 1.00 81.62 ? 114 GLN P N 1 +ATOM 29432 C CA . GLN P 1 114 ? 2.757 6.080 44.329 1.00 84.65 ? 114 GLN P CA 1 +ATOM 29433 C C . GLN P 1 114 ? 3.805 6.597 43.393 1.00 79.04 ? 114 GLN P C 1 +ATOM 29434 O O . GLN P 1 114 ? 4.509 7.552 43.742 1.00 129.03 ? 114 GLN P O 1 +ATOM 29435 C CB . GLN P 1 114 ? 1.453 6.828 44.102 1.00 81.85 ? 114 GLN P CB 1 +ATOM 29436 C CG . GLN P 1 114 ? 0.513 6.188 43.104 1.00 76.59 ? 114 GLN P CG 1 +ATOM 29437 C CD . GLN P 1 114 ? -0.267 7.240 42.358 1.00 67.42 ? 114 GLN P CD 1 +ATOM 29438 O OE1 . GLN P 1 114 ? -0.455 7.125 41.155 1.00 57.20 ? 114 GLN P OE1 1 +ATOM 29439 N NE2 . GLN P 1 114 ? -0.656 8.310 43.059 1.00 67.65 ? 114 GLN P NE2 1 +ATOM 29440 N N . SER P 1 115 ? 3.990 5.916 42.269 1.00 59.00 ? 115 SER P N 1 +ATOM 29441 C CA . SER P 1 115 ? 5.055 6.267 41.349 1.00 69.58 ? 115 SER P CA 1 +ATOM 29442 C C . SER P 1 115 ? 4.898 7.721 40.917 1.00 83.97 ? 115 SER P C 1 +ATOM 29443 O O . SER P 1 115 ? 3.774 8.275 40.993 1.00 126.25 ? 115 SER P O 1 +ATOM 29444 C CB . SER P 1 115 ? 5.023 5.347 40.141 1.00 67.51 ? 115 SER P CB 1 +ATOM 29445 O OG . SER P 1 115 ? 3.731 5.268 39.583 1.00 64.37 ? 115 SER P OG 1 +ATOM 29446 N N . LEU P 1 116 ? 5.996 8.381 40.528 1.00 67.11 ? 116 LEU P N 1 +ATOM 29447 C CA . LEU P 1 116 ? 5.891 9.823 40.354 1.00 79.44 ? 116 LEU P CA 1 +ATOM 29448 C C . LEU P 1 116 ? 5.046 10.051 39.121 1.00 92.29 ? 116 LEU P C 1 +ATOM 29449 O O . LEU P 1 116 ? 5.359 9.490 38.069 1.00 132.52 ? 116 LEU P O 1 +ATOM 29450 C CB . LEU P 1 116 ? 7.241 10.486 40.207 1.00 76.35 ? 116 LEU P CB 1 +ATOM 29451 C CG . LEU P 1 116 ? 8.129 10.430 41.431 1.00 99.64 ? 116 LEU P CG 1 +ATOM 29452 C CD1 . LEU P 1 116 ? 9.086 9.229 41.386 1.00 128.96 ? 116 LEU P CD1 1 +ATOM 29453 C CD2 . LEU P 1 116 ? 8.902 11.742 41.503 1.00 113.68 ? 116 LEU P CD2 1 +ATOM 29454 N N . THR P 1 117 ? 3.966 10.824 39.259 1.00 89.26 ? 117 THR P N 1 +ATOM 29455 C CA . THR P 1 117 ? 3.127 11.180 38.128 1.00 113.91 ? 117 THR P CA 1 +ATOM 29456 C C . THR P 1 117 ? 3.968 11.830 37.029 1.00 122.04 ? 117 THR P C 1 +ATOM 29457 O O . THR P 1 117 ? 4.815 12.674 37.321 1.00 121.36 ? 117 THR P O 1 +ATOM 29458 C CB . THR P 1 117 ? 2.048 12.194 38.520 1.00 139.83 ? 117 THR P CB 1 +ATOM 29459 O OG1 . THR P 1 117 ? 1.303 11.688 39.637 1.00 192.28 ? 117 THR P OG1 1 +ATOM 29460 C CG2 . THR P 1 117 ? 1.098 12.417 37.362 1.00 129.67 ? 117 THR P CG2 1 +ATOM 29461 N N . ALA P 1 118 ? 3.764 11.390 35.784 1.00 111.90 ? 118 ALA P N 1 +ATOM 29462 C CA . ALA P 1 118 ? 4.707 11.675 34.692 1.00 85.83 ? 118 ALA P CA 1 +ATOM 29463 C C . ALA P 1 118 ? 4.038 12.428 33.631 1.00 79.55 ? 118 ALA P C 1 +ATOM 29464 O O . ALA P 1 118 ? 2.889 12.132 33.266 1.00 61.80 ? 118 ALA P O 1 +ATOM 29465 C CB . ALA P 1 118 ? 5.278 10.400 34.098 1.00 103.32 ? 118 ALA P CB 1 +ATOM 29466 N N . ALA P 1 119 ? 4.781 13.386 33.103 1.00 101.13 ? 119 ALA P N 1 +ATOM 29467 C CA . ALA P 1 119 ? 4.240 14.362 32.160 1.00 107.53 ? 119 ALA P CA 1 +ATOM 29468 C C . ALA P 1 119 ? 4.329 13.857 30.721 1.00 97.80 ? 119 ALA P C 1 +ATOM 29469 O O . ALA P 1 119 ? 5.162 13.001 30.413 1.00 60.87 ? 119 ALA P O 1 +ATOM 29470 C CB . ALA P 1 119 ? 4.999 15.659 32.276 1.00 110.05 ? 119 ALA P CB 1 +ATOM 29471 N N . ASN P 1 120 ? 3.438 14.353 29.857 1.00 87.00 ? 120 ASN P N 1 +ATOM 29472 C CA . ASN P 1 120 ? 3.486 13.984 28.437 1.00 88.96 ? 120 ASN P CA 1 +ATOM 29473 C C . ASN P 1 120 ? 4.163 15.028 27.592 1.00 83.37 ? 120 ASN P C 1 +ATOM 29474 O O . ASN P 1 120 ? 4.995 14.729 26.749 1.00 87.54 ? 120 ASN P O 1 +ATOM 29475 C CB . ASN P 1 120 ? 2.093 13.747 27.860 1.00 106.19 ? 120 ASN P CB 1 +ATOM 29476 C CG . ASN P 1 120 ? 2.137 13.385 26.384 1.00 125.44 ? 120 ASN P CG 1 +ATOM 29477 O OD1 . ASN P 1 120 ? 3.045 12.670 25.918 1.00 130.00 ? 120 ASN P OD1 1 +ATOM 29478 N ND2 . ASN P 1 120 ? 1.161 13.898 25.630 1.00 135.13 ? 120 ASN P ND2 1 +ATOM 29479 N N . ILE P 1 121 ? 3.776 16.272 27.793 1.00 76.42 ? 121 ILE P N 1 +ATOM 29480 C CA . ILE P 1 121 ? 4.499 17.351 27.181 1.00 86.52 ? 121 ILE P CA 1 +ATOM 29481 C C . ILE P 1 121 ? 5.274 18.061 28.275 1.00 85.20 ? 121 ILE P C 1 +ATOM 29482 O O . ILE P 1 121 ? 4.799 18.252 29.384 1.00 97.99 ? 121 ILE P O 1 +ATOM 29483 C CB . ILE P 1 121 ? 3.557 18.314 26.413 1.00 113.42 ? 121 ILE P CB 1 +ATOM 29484 C CG1 . ILE P 1 121 ? 2.730 19.209 27.360 1.00 136.99 ? 121 ILE P CG1 1 +ATOM 29485 C CG2 . ILE P 1 121 ? 2.646 17.529 25.472 1.00 105.49 ? 121 ILE P CG2 1 +ATOM 29486 C CD1 . ILE P 1 121 ? 3.126 20.675 27.331 1.00 131.03 ? 121 ILE P CD1 1 +ATOM 29487 N N . MET P 1 122 ? 6.463 18.491 27.950 1.00 88.14 ? 122 MET P N 1 +ATOM 29488 C CA . MET P 1 122 ? 7.091 19.442 28.797 1.00 104.92 ? 122 MET P CA 1 +ATOM 29489 C C . MET P 1 122 ? 7.303 20.741 28.006 1.00 82.57 ? 122 MET P C 1 +ATOM 29490 O O . MET P 1 122 ? 7.681 20.705 26.839 1.00 87.81 ? 122 MET P O 1 +ATOM 29491 C CB . MET P 1 122 ? 8.371 18.817 29.402 1.00 144.79 ? 122 MET P CB 1 +ATOM 29492 C CG . MET P 1 122 ? 9.420 18.302 28.424 1.00 137.20 ? 122 MET P CG 1 +ATOM 29493 S SD . MET P 1 122 ? 11.074 18.459 29.177 1.00 99.51 ? 122 MET P SD 1 +ATOM 29494 C CE . MET P 1 122 ? 12.052 18.961 27.795 1.00 110.61 ? 122 MET P CE 1 +ATOM 29495 N N . VAL P 1 123 ? 7.175 21.875 28.689 1.00 48.59 ? 123 VAL P N 1 +ATOM 29496 C CA . VAL P 1 123 ? 7.498 23.148 28.084 1.00 45.72 ? 123 VAL P CA 1 +ATOM 29497 C C . VAL P 1 123 ? 8.670 23.885 28.708 1.00 48.30 ? 123 VAL P C 1 +ATOM 29498 O O . VAL P 1 123 ? 8.763 24.019 29.927 1.00 58.98 ? 123 VAL P O 1 +ATOM 29499 C CB . VAL P 1 123 ? 6.316 24.057 28.170 1.00 53.01 ? 123 VAL P CB 1 +ATOM 29500 C CG1 . VAL P 1 123 ? 5.647 23.940 29.529 1.00 50.20 ? 123 VAL P CG1 1 +ATOM 29501 C CG2 . VAL P 1 123 ? 6.710 25.513 27.854 1.00 68.01 ? 123 VAL P CG2 1 +ATOM 29502 N N . GLU P 1 124 ? 9.623 24.310 27.875 1.00 66.78 ? 124 GLU P N 1 +ATOM 29503 C CA . GLU P 1 124 ? 10.780 25.072 28.354 1.00 93.44 ? 124 GLU P CA 1 +ATOM 29504 C C . GLU P 1 124 ? 10.979 26.266 27.473 1.00 90.38 ? 124 GLU P C 1 +ATOM 29505 O O . GLU P 1 124 ? 10.332 26.413 26.462 1.00 59.07 ? 124 GLU P O 1 +ATOM 29506 C CB . GLU P 1 124 ? 12.092 24.264 28.383 1.00 121.87 ? 124 GLU P CB 1 +ATOM 29507 C CG . GLU P 1 124 ? 12.215 23.164 27.346 1.00 135.29 ? 124 GLU P CG 1 +ATOM 29508 C CD . GLU P 1 124 ? 13.298 22.160 27.704 1.00 152.68 ? 124 GLU P CD 1 +ATOM 29509 O OE1 . GLU P 1 124 ? 13.491 21.877 28.906 1.00 131.04 ? 124 GLU P OE1 1 +ATOM 29510 O OE2 . GLU P 1 124 ? 13.985 21.707 26.771 1.00 193.67 ? 124 GLU P OE2 1 +ATOM 29511 N N . GLY P 1 125 ? 11.828 27.175 27.935 1.00 114.67 ? 125 GLY P N 1 +ATOM 29512 C CA . GLY P 1 125 ? 11.990 28.468 27.287 1.00 100.84 ? 125 GLY P CA 1 +ATOM 29513 C C . GLY P 1 125 ? 13.114 29.277 27.892 1.00 67.04 ? 125 GLY P C 1 +ATOM 29514 O O . GLY P 1 125 ? 13.969 28.737 28.586 1.00 65.73 ? 125 GLY P O 1 +ATOM 29515 N N . SER P 1 126 ? 13.110 30.567 27.623 1.00 54.64 ? 126 SER P N 1 +ATOM 29516 C CA . SER P 1 126 ? 14.233 31.385 28.005 1.00 67.38 ? 126 SER P CA 1 +ATOM 29517 C C . SER P 1 126 ? 13.839 32.825 27.977 1.00 93.51 ? 126 SER P C 1 +ATOM 29518 O O . SER P 1 126 ? 12.958 33.224 27.191 1.00 123.74 ? 126 SER P O 1 +ATOM 29519 C CB . SER P 1 126 ? 15.406 31.231 27.032 1.00 65.84 ? 126 SER P CB 1 +ATOM 29520 O OG . SER P 1 126 ? 15.476 29.934 26.465 1.00 59.42 ? 126 SER P OG 1 +ATOM 29521 N N . ILE P 1 127 ? 14.449 33.624 28.854 1.00 78.06 ? 127 ILE P N 1 +ATOM 29522 C CA . ILE P 1 127 ? 14.276 35.063 28.755 1.00 90.33 ? 127 ILE P CA 1 +ATOM 29523 C C . ILE P 1 127 ? 15.264 35.469 27.691 1.00 91.79 ? 127 ILE P C 1 +ATOM 29524 O O . ILE P 1 127 ? 16.441 35.557 27.954 1.00 67.65 ? 127 ILE P O 1 +ATOM 29525 C CB . ILE P 1 127 ? 14.503 35.829 30.088 1.00 73.85 ? 127 ILE P CB 1 +ATOM 29526 C CG1 . ILE P 1 127 ? 13.364 35.537 31.090 1.00 53.06 ? 127 ILE P CG1 1 +ATOM 29527 C CG2 . ILE P 1 127 ? 14.557 37.330 29.828 1.00 83.52 ? 127 ILE P CG2 1 +ATOM 29528 C CD1 . ILE P 1 127 ? 13.816 35.598 32.523 1.00 47.84 ? 127 ILE P CD1 1 +ATOM 29529 N N . ILE P 1 128 ? 14.743 35.730 26.489 1.00 103.83 ? 128 ILE P N 1 +ATOM 29530 C CA . ILE P 1 128 ? 15.543 36.140 25.331 1.00 107.16 ? 128 ILE P CA 1 +ATOM 29531 C C . ILE P 1 128 ? 15.549 37.658 25.267 1.00 83.06 ? 128 ILE P C 1 +ATOM 29532 O O . ILE P 1 128 ? 14.511 38.312 25.030 1.00 183.42 ? 128 ILE P O 1 +ATOM 29533 C CB . ILE P 1 128 ? 14.979 35.524 24.035 1.00 147.39 ? 128 ILE P CB 1 +ATOM 29534 C CG1 . ILE P 1 128 ? 13.490 35.844 23.870 1.00 188.42 ? 128 ILE P CG1 1 +ATOM 29535 C CG2 . ILE P 1 128 ? 15.074 34.008 24.092 1.00 174.26 ? 128 ILE P CG2 1 +ATOM 29536 C CD1 . ILE P 1 128 ? 13.036 35.813 22.421 1.00 223.61 ? 128 ILE P CD1 1 +ATOM 29537 N N . GLY P 1 129 ? 16.609 38.224 25.804 1.00 75.26 ? 129 GLY P N 1 +ATOM 29538 C CA . GLY P 1 129 ? 16.790 39.659 25.714 1.00 118.59 ? 129 GLY P CA 1 +ATOM 29539 C C . GLY P 1 129 ? 16.107 40.612 26.718 1.00 145.17 ? 129 GLY P C 1 +ATOM 29540 O O . GLY P 1 129 ? 14.918 40.499 27.062 1.00 115.69 ? 129 GLY P O 1 +ATOM 29541 N N . TYR P 1 130 ? 16.894 41.588 27.157 1.00 145.39 ? 130 TYR P N 1 +ATOM 29542 C CA . TYR P 1 130 ? 16.379 42.789 27.793 1.00 116.34 ? 130 TYR P CA 1 +ATOM 29543 C C . TYR P 1 130 ? 17.227 43.921 27.257 1.00 108.59 ? 130 TYR P C 1 +ATOM 29544 O O . TYR P 1 130 ? 18.424 43.995 27.545 1.00 143.30 ? 130 TYR P O 1 +ATOM 29545 C CB . TYR P 1 130 ? 16.517 42.676 29.315 1.00 106.59 ? 130 TYR P CB 1 +ATOM 29546 C CG . TYR P 1 130 ? 16.163 43.912 30.110 1.00 113.07 ? 130 TYR P CG 1 +ATOM 29547 C CD1 . TYR P 1 130 ? 16.968 45.060 30.061 1.00 111.97 ? 130 TYR P CD1 1 +ATOM 29548 C CD2 . TYR P 1 130 ? 15.071 43.909 30.980 1.00 118.02 ? 130 TYR P CD2 1 +ATOM 29549 C CE1 . TYR P 1 130 ? 16.653 46.188 30.810 1.00 122.19 ? 130 TYR P CE1 1 +ATOM 29550 C CE2 . TYR P 1 130 ? 14.756 45.025 31.749 1.00 139.11 ? 130 TYR P CE2 1 +ATOM 29551 C CZ . TYR P 1 130 ? 15.553 46.159 31.668 1.00 137.00 ? 130 TYR P CZ 1 +ATOM 29552 O OH . TYR P 1 130 ? 15.161 47.277 32.362 1.00 101.67 ? 130 TYR P OH 1 +ATOM 29553 N N . GLU P 1 131 ? 16.659 44.718 26.375 1.00 84.18 ? 131 GLU P N 1 +ATOM 29554 C CA . GLU P 1 131 ? 17.342 45.912 25.942 1.00 108.38 ? 131 GLU P CA 1 +ATOM 29555 C C . GLU P 1 131 ? 16.834 47.076 26.786 1.00 120.18 ? 131 GLU P C 1 +ATOM 29556 O O . GLU P 1 131 ? 15.681 47.087 27.206 1.00 76.99 ? 131 GLU P O 1 +ATOM 29557 C CB . GLU P 1 131 ? 17.096 46.132 24.459 1.00 139.86 ? 131 GLU P CB 1 +ATOM 29558 C CG . GLU P 1 131 ? 17.923 47.232 23.814 1.00 148.32 ? 131 GLU P CG 1 +ATOM 29559 C CD . GLU P 1 131 ? 19.289 46.770 23.324 1.00 163.31 ? 131 GLU P CD 1 +ATOM 29560 O OE1 . GLU P 1 131 ? 19.440 45.576 22.971 1.00 181.95 ? 131 GLU P OE1 1 +ATOM 29561 O OE2 . GLU P 1 131 ? 20.209 47.620 23.249 1.00 202.22 ? 131 GLU P OE2 1 +ATOM 29562 N N . SER P 1 132 ? 17.713 48.042 27.063 1.00 138.50 ? 132 SER P N 1 +ATOM 29563 C CA . SER P 1 132 ? 17.393 49.116 28.003 1.00 130.99 ? 132 SER P CA 1 +ATOM 29564 C C . SER P 1 132 ? 17.414 50.507 27.336 1.00 150.19 ? 132 SER P C 1 +ATOM 29565 O O . SER P 1 132 ? 18.283 50.796 26.504 1.00 110.39 ? 132 SER P O 1 +ATOM 29566 C CB . SER P 1 132 ? 18.350 49.080 29.186 1.00 120.51 ? 132 SER P CB 1 +ATOM 29567 O OG . SER P 1 132 ? 19.195 50.220 29.191 1.00 164.84 ? 132 SER P OG 1 +ATOM 29568 N N . ASN P 1 133 ? 16.462 51.361 27.727 1.00 154.48 ? 133 ASN P N 1 +ATOM 29569 C CA . ASN P 1 133 ? 16.217 52.651 27.061 1.00 126.85 ? 133 ASN P CA 1 +ATOM 29570 C C . ASN P 1 133 ? 16.109 52.494 25.562 1.00 145.51 ? 133 ASN P C 1 +ATOM 29571 O O . ASN P 1 133 ? 16.891 53.086 24.799 1.00 143.72 ? 133 ASN P O 1 +ATOM 29572 C CB . ASN P 1 133 ? 17.305 53.672 27.394 1.00 101.76 ? 133 ASN P CB 1 +ATOM 29573 C CG . ASN P 1 133 ? 17.370 53.988 28.870 1.00 114.27 ? 133 ASN P CG 1 +ATOM 29574 O OD1 . ASN P 1 133 ? 16.375 53.875 29.609 1.00 83.64 ? 133 ASN P OD1 1 +ATOM 29575 N ND2 . ASN P 1 133 ? 18.565 54.333 29.330 1.00 152.30 ? 133 ASN P ND2 1 +ATOM 29576 N N . VAL P 1 134 ? 15.185 51.627 25.152 1.00 128.27 ? 134 VAL P N 1 +ATOM 29577 C CA . VAL P 1 134 ? 14.992 51.321 23.740 1.00 134.64 ? 134 VAL P CA 1 +ATOM 29578 C C . VAL P 1 134 ? 14.433 52.584 23.119 1.00 134.36 ? 134 VAL P C 1 +ATOM 29579 O O . VAL P 1 134 ? 14.728 52.929 21.968 1.00 65.94 ? 134 VAL P O 1 +ATOM 29580 C CB . VAL P 1 134 ? 14.041 50.114 23.560 1.00 127.11 ? 134 VAL P CB 1 +ATOM 29581 C CG1 . VAL P 1 134 ? 13.870 49.769 22.084 1.00 118.02 ? 134 VAL P CG1 1 +ATOM 29582 C CG2 . VAL P 1 134 ? 14.578 48.894 24.310 1.00 160.34 ? 134 VAL P CG2 1 +ATOM 29583 N N . LYS P 1 135 ? 13.627 53.284 23.917 1.00 179.72 ? 135 LYS P N 1 +ATOM 29584 C CA . LYS P 1 135 ? 13.256 54.661 23.605 1.00 202.45 ? 135 LYS P CA 1 +ATOM 29585 C C . LYS P 1 135 ? 13.324 55.545 24.850 1.00 164.41 ? 135 LYS P C 1 +ATOM 29586 O O . LYS P 1 135 ? 13.220 55.070 25.984 1.00 83.14 ? 135 LYS P O 1 +ATOM 29587 C CB . LYS P 1 135 ? 11.842 54.725 23.008 1.00 241.70 ? 135 LYS P CB 1 +ATOM 29588 C CG . LYS P 1 135 ? 11.691 53.987 21.685 1.00 234.58 ? 135 LYS P CG 1 +ATOM 29589 C CD . LYS P 1 135 ? 10.244 54.004 21.222 1.00 209.16 ? 135 LYS P CD 1 +ATOM 29590 C CE . LYS P 1 135 ? 10.064 53.254 19.919 1.00 195.73 ? 135 LYS P CE 1 +ATOM 29591 N NZ . LYS P 1 135 ? 8.818 53.686 19.242 1.00 187.91 ? 135 LYS P NZ 1 +ATOM 29592 N N . SER P 1 136 ? 13.440 56.846 24.610 1.00 163.14 ? 136 SER P N 1 +ATOM 29593 C CA . SER P 1 136 ? 13.480 57.813 25.686 1.00 137.24 ? 136 SER P CA 1 +ATOM 29594 C C . SER P 1 136 ? 13.221 59.215 25.170 1.00 137.24 ? 136 SER P C 1 +ATOM 29595 O O . SER P 1 136 ? 13.386 59.502 23.985 1.00 79.02 ? 136 SER P O 1 +ATOM 29596 C CB . SER P 1 136 ? 14.821 57.758 26.402 1.00 124.79 ? 136 SER P CB 1 +ATOM 29597 O OG . SER P 1 136 ? 15.455 59.022 26.409 1.00 125.11 ? 136 SER P OG 1 +ATOM 29598 N N . GLY P 1 137 ? 12.786 60.084 26.075 1.00 180.96 ? 137 GLY P N 1 +ATOM 29599 C CA . GLY P 1 137 ? 12.532 61.478 25.728 1.00 215.06 ? 137 GLY P CA 1 +ATOM 29600 C C . GLY P 1 137 ? 12.379 62.381 26.940 1.00 202.41 ? 137 GLY P C 1 +ATOM 29601 O O . GLY P 1 137 ? 12.306 61.911 28.069 1.00 140.43 ? 137 GLY P O 1 +ATOM 29602 N N . GLY P 1 138 ? 12.290 63.682 26.688 1.00 189.69 ? 138 GLY P N 1 +ATOM 29603 C CA . GLY P 1 138 ? 12.041 64.642 27.749 1.00 168.33 ? 138 GLY P CA 1 +ATOM 29604 C C . GLY P 1 138 ? 11.577 65.986 27.229 1.00 173.16 ? 138 GLY P C 1 +ATOM 29605 O O . GLY P 1 138 ? 11.958 66.411 26.136 1.00 138.05 ? 138 GLY P O 1 +ATOM 29606 N N . VAL P 1 139 ? 10.693 66.627 27.990 1.00 189.75 ? 139 VAL P N 1 +ATOM 29607 C CA . VAL P 1 139 ? 10.194 67.958 27.654 1.00 177.47 ? 139 VAL P CA 1 +ATOM 29608 C C . VAL P 1 139 ? 10.139 68.810 28.916 1.00 184.04 ? 139 VAL P C 1 +ATOM 29609 O O . VAL P 1 139 ? 9.519 68.428 29.909 1.00 169.12 ? 139 VAL P O 1 +ATOM 29610 C CB . VAL P 1 139 ? 8.786 67.912 27.027 1.00 151.76 ? 139 VAL P CB 1 +ATOM 29611 C CG1 . VAL P 1 139 ? 8.266 69.321 26.825 1.00 152.01 ? 139 VAL P CG1 1 +ATOM 29612 C CG2 . VAL P 1 139 ? 8.810 67.157 25.706 1.00 148.22 ? 139 VAL P CG2 1 +ATOM 29613 N N . GLY P 1 140 ? 10.782 69.973 28.861 1.00 198.79 ? 140 GLY P N 1 +ATOM 29614 C CA . GLY P 1 140 ? 10.826 70.879 29.999 1.00 199.82 ? 140 GLY P CA 1 +ATOM 29615 C C . GLY P 1 140 ? 10.900 72.343 29.607 1.00 204.14 ? 140 GLY P C 1 +ATOM 29616 O O . GLY P 1 140 ? 11.543 72.707 28.620 1.00 189.97 ? 140 GLY P O 1 +ATOM 29617 N N . ALA P 1 141 ? 10.250 73.187 30.399 1.00 197.91 ? 141 ALA P N 1 +ATOM 29618 C CA . ALA P 1 141 ? 10.287 74.623 30.166 1.00 175.82 ? 141 ALA P CA 1 +ATOM 29619 C C . ALA P 1 141 ? 10.311 75.406 31.476 1.00 185.54 ? 141 ALA P C 1 +ATOM 29620 O O . ALA P 1 141 ? 9.655 75.037 32.460 1.00 129.87 ? 141 ALA P O 1 +ATOM 29621 C CB . ALA P 1 141 ? 9.112 75.047 29.306 1.00 157.01 ? 141 ALA P CB 1 +ATOM 29622 N N . ARG P 1 142 ? 11.120 76.456 31.496 1.00 195.79 ? 142 ARG P N 1 +ATOM 29623 C CA . ARG P 1 142 ? 11.133 77.368 32.618 1.00 192.43 ? 142 ARG P CA 1 +ATOM 29624 C C . ARG P 1 142 ? 10.975 78.781 32.090 1.00 204.92 ? 142 ARG P C 1 +ATOM 29625 O O . ARG P 1 142 ? 11.458 79.108 31.005 1.00 171.11 ? 142 ARG P O 1 +ATOM 29626 C CB . ARG P 1 142 ? 12.416 77.225 33.443 1.00 172.41 ? 142 ARG P CB 1 +ATOM 29627 C CG . ARG P 1 142 ? 12.423 78.101 34.687 1.00 161.47 ? 142 ARG P CG 1 +ATOM 29628 C CD . ARG P 1 142 ? 12.967 77.390 35.915 1.00 157.67 ? 142 ARG P CD 1 +ATOM 29629 N NE . ARG P 1 142 ? 14.409 77.512 36.063 1.00 184.60 ? 142 ARG P NE 1 +ATOM 29630 C CZ . ARG P 1 142 ? 15.170 76.685 36.774 1.00 187.66 ? 142 ARG P CZ 1 +ATOM 29631 N NH1 . ARG P 1 142 ? 14.652 75.592 37.320 1.00 182.25 ? 142 ARG P NH1 1 +ATOM 29632 N NH2 . ARG P 1 142 ? 16.472 76.925 36.895 1.00 180.54 ? 142 ARG P NH2 1 +ATOM 29633 N N . TYR P 1 143 ? 10.247 79.597 32.847 1.00 237.47 ? 143 TYR P N 1 +ATOM 29634 C CA . TYR P 1 143 ? 9.868 80.936 32.414 1.00 236.88 ? 143 TYR P CA 1 +ATOM 29635 C C . TYR P 1 143 ? 10.186 81.962 33.504 1.00 237.72 ? 143 TYR P C 1 +ATOM 29636 O O . TYR P 1 143 ? 9.322 82.363 34.286 1.00 229.02 ? 143 TYR P O 1 +ATOM 29637 C CB . TYR P 1 143 ? 8.379 80.965 32.057 1.00 224.57 ? 143 TYR P CB 1 +ATOM 29638 C CG . TYR P 1 143 ? 7.939 82.270 31.469 1.00 220.43 ? 143 TYR P CG 1 +ATOM 29639 C CD1 . TYR P 1 143 ? 8.351 82.649 30.200 1.00 205.42 ? 143 TYR P CD1 1 +ATOM 29640 C CD2 . TYR P 1 143 ? 7.142 83.144 32.195 1.00 219.30 ? 143 TYR P CD2 1 +ATOM 29641 C CE1 . TYR P 1 143 ? 7.967 83.861 29.659 1.00 222.18 ? 143 TYR P CE1 1 +ATOM 29642 C CE2 . TYR P 1 143 ? 6.746 84.358 31.664 1.00 228.58 ? 143 TYR P CE2 1 +ATOM 29643 C CZ . TYR P 1 143 ? 7.163 84.712 30.395 1.00 238.88 ? 143 TYR P CZ 1 +ATOM 29644 O OH . TYR P 1 143 ? 6.781 85.920 29.859 1.00 258.74 ? 143 TYR P OH 1 +ATOM 29645 N N . GLY P 1 145 ? 10.919 82.311 36.092 1.00 123.60 ? 145 GLY P N 1 +ATOM 29646 C CA . GLY P 1 145 ? 10.877 81.890 37.481 1.00 161.34 ? 145 GLY P CA 1 +ATOM 29647 C C . GLY P 1 145 ? 10.207 80.546 37.749 1.00 194.94 ? 145 GLY P C 1 +ATOM 29648 O O . GLY P 1 145 ? 10.555 79.885 38.731 1.00 208.04 ? 145 GLY P O 1 +ATOM 29649 N N . ILE P 1 146 ? 9.262 80.139 36.896 1.00 206.49 ? 146 ILE P N 1 +ATOM 29650 C CA . ILE P 1 146 ? 8.437 78.936 37.128 1.00 200.58 ? 146 ILE P CA 1 +ATOM 29651 C C . ILE P 1 146 ? 8.751 77.882 36.057 1.00 223.63 ? 146 ILE P C 1 +ATOM 29652 O O . ILE P 1 146 ? 8.915 78.219 34.888 1.00 165.46 ? 146 ILE P O 1 +ATOM 29653 C CB . ILE P 1 146 ? 6.920 79.256 37.093 1.00 170.21 ? 146 ILE P CB 1 +ATOM 29654 C CG1 . ILE P 1 146 ? 6.637 80.603 37.773 1.00 160.08 ? 146 ILE P CG1 1 +ATOM 29655 C CG2 . ILE P 1 146 ? 6.115 78.143 37.759 1.00 141.80 ? 146 ILE P CG2 1 +ATOM 29656 C CD1 . ILE P 1 146 ? 6.537 81.772 36.814 1.00 132.03 ? 146 ILE P CD1 1 +ATOM 29657 N N . GLY P 1 147 ? 8.878 76.614 36.449 1.00 257.49 ? 147 GLY P N 1 +ATOM 29658 C CA . GLY P 1 147 ? 9.285 75.576 35.497 1.00 235.78 ? 147 GLY P CA 1 +ATOM 29659 C C . GLY P 1 147 ? 8.763 74.181 35.767 1.00 238.53 ? 147 GLY P C 1 +ATOM 29660 O O . GLY P 1 147 ? 8.451 73.823 36.902 1.00 261.29 ? 147 GLY P O 1 +ATOM 29661 N N . ALA P 1 148 ? 8.678 73.384 34.710 1.00 220.42 ? 148 ALA P N 1 +ATOM 29662 C CA . ALA P 1 148 ? 8.359 71.971 34.849 1.00 201.63 ? 148 ALA P CA 1 +ATOM 29663 C C . ALA P 1 148 ? 9.068 71.160 33.773 1.00 189.84 ? 148 ALA P C 1 +ATOM 29664 O O . ALA P 1 148 ? 9.626 71.717 32.821 1.00 190.75 ? 148 ALA P O 1 +ATOM 29665 C CB . ALA P 1 148 ? 6.855 71.754 34.788 1.00 170.04 ? 148 ALA P CB 1 +ATOM 29666 N N . ASP P 1 149 ? 9.097 69.848 33.966 1.00 172.95 ? 149 ASP P N 1 +ATOM 29667 C CA . ASP P 1 149 ? 9.684 68.954 32.977 1.00 168.37 ? 149 ASP P CA 1 +ATOM 29668 C C . ASP P 1 149 ? 9.259 67.507 33.235 1.00 179.75 ? 149 ASP P C 1 +ATOM 29669 O O . ASP P 1 149 ? 9.012 67.113 34.377 1.00 111.93 ? 149 ASP P O 1 +ATOM 29670 C CB . ASP P 1 149 ? 11.211 69.071 32.971 1.00 159.13 ? 149 ASP P CB 1 +ATOM 29671 C CG . ASP P 1 149 ? 11.852 68.281 34.075 1.00 175.88 ? 149 ASP P CG 1 +ATOM 29672 O OD1 . ASP P 1 149 ? 11.784 68.726 35.236 1.00 170.39 ? 149 ASP P OD1 1 +ATOM 29673 O OD2 . ASP P 1 149 ? 12.413 67.213 33.779 1.00 176.43 ? 149 ASP P OD2 1 +ATOM 29674 N N . THR P 1 150 ? 9.100 66.742 32.161 1.00 196.31 ? 150 THR P N 1 +ATOM 29675 C CA . THR P 1 150 ? 8.991 65.297 32.290 1.00 159.63 ? 150 THR P CA 1 +ATOM 29676 C C . THR P 1 150 ? 10.113 64.646 31.492 1.00 179.92 ? 150 THR P C 1 +ATOM 29677 O O . THR P 1 150 ? 10.623 65.220 30.531 1.00 196.47 ? 150 THR P O 1 +ATOM 29678 C CB . THR P 1 150 ? 7.621 64.763 31.823 1.00 123.15 ? 150 THR P CB 1 +ATOM 29679 O OG1 . THR P 1 150 ? 7.404 65.117 30.451 1.00 143.35 ? 150 THR P OG1 1 +ATOM 29680 C CG2 . THR P 1 150 ? 6.499 65.315 32.672 1.00 107.14 ? 150 THR P CG2 1 +ATOM 29681 N N . GLN P 1 151 ? 10.503 63.456 31.914 1.00 181.41 ? 151 GLN P N 1 +ATOM 29682 C CA . GLN P 1 151 ? 11.390 62.623 31.101 1.00 164.69 ? 151 GLN P CA 1 +ATOM 29683 C C . GLN P 1 151 ? 10.863 61.183 31.167 1.00 187.48 ? 151 GLN P C 1 +ATOM 29684 O O . GLN P 1 151 ? 10.238 60.758 32.149 1.00 180.83 ? 151 GLN P O 1 +ATOM 29685 C CB . GLN P 1 151 ? 12.881 62.774 31.486 1.00 165.24 ? 151 GLN P CB 1 +ATOM 29686 C CG . GLN P 1 151 ? 13.246 62.175 32.832 1.00 186.67 ? 151 GLN P CG 1 +ATOM 29687 C CD . GLN P 1 151 ? 14.738 61.958 33.016 1.00 191.02 ? 151 GLN P CD 1 +ATOM 29688 O OE1 . GLN P 1 151 ? 15.549 62.762 32.553 1.00 213.29 ? 151 GLN P OE1 1 +ATOM 29689 N NE2 . GLN P 1 151 ? 15.113 60.845 33.656 1.00 182.16 ? 151 GLN P NE2 1 +ATOM 29690 N N . TYR P 1 152 ? 10.968 60.476 30.058 1.00 178.50 ? 152 TYR P N 1 +ATOM 29691 C CA . TYR P 1 152 ? 10.510 59.096 30.024 1.00 193.85 ? 152 TYR P CA 1 +ATOM 29692 C C . TYR P 1 152 ? 11.525 58.187 29.359 1.00 239.78 ? 152 TYR P C 1 +ATOM 29693 O O . TYR P 1 152 ? 12.243 58.611 28.454 1.00 239.14 ? 152 TYR P O 1 +ATOM 29694 C CB . TYR P 1 152 ? 9.144 58.990 29.345 1.00 143.37 ? 152 TYR P CB 1 +ATOM 29695 C CG . TYR P 1 152 ? 9.127 58.449 27.935 1.00 138.14 ? 152 TYR P CG 1 +ATOM 29696 C CD1 . TYR P 1 152 ? 9.747 59.127 26.882 1.00 141.08 ? 152 TYR P CD1 1 +ATOM 29697 C CD2 . TYR P 1 152 ? 8.418 57.296 27.635 1.00 127.09 ? 152 TYR P CD2 1 +ATOM 29698 C CE1 . TYR P 1 152 ? 9.738 58.612 25.583 1.00 126.05 ? 152 TYR P CE1 1 +ATOM 29699 C CE2 . TYR P 1 152 ? 8.360 56.800 26.335 1.00 133.21 ? 152 TYR P CE2 1 +ATOM 29700 C CZ . TYR P 1 152 ? 9.030 57.455 25.313 1.00 123.25 ? 152 TYR P CZ 1 +ATOM 29701 O OH . TYR P 1 152 ? 8.943 56.974 24.028 1.00 89.36 ? 152 TYR P OH 1 +ATOM 29702 N N . GLN P 1 153 ? 11.621 56.954 29.856 1.00 237.35 ? 153 GLN P N 1 +ATOM 29703 C CA . GLN P 1 153 ? 12.419 55.929 29.197 1.00 197.59 ? 153 GLN P CA 1 +ATOM 29704 C C . GLN P 1 153 ? 11.636 54.626 29.142 1.00 169.71 ? 153 GLN P C 1 +ATOM 29705 O O . GLN P 1 153 ? 10.732 54.393 29.952 1.00 106.12 ? 153 GLN P O 1 +ATOM 29706 C CB . GLN P 1 153 ? 13.741 55.715 29.943 1.00 206.73 ? 153 GLN P CB 1 +ATOM 29707 C CG . GLN P 1 153 ? 14.671 56.922 29.904 1.00 202.85 ? 153 GLN P CG 1 +ATOM 29708 C CD . GLN P 1 153 ? 14.358 58.013 30.949 1.00 169.97 ? 153 GLN P CD 1 +ATOM 29709 O OE1 . GLN P 1 153 ? 13.466 57.863 31.792 1.00 132.38 ? 153 GLN P OE1 1 +ATOM 29710 N NE2 . GLN P 1 153 ? 15.144 59.086 30.931 1.00 134.11 ? 153 GLN P NE2 1 +ATOM 29711 N N . LEU P 1 154 ? 11.928 53.807 28.135 1.00 186.47 ? 154 LEU P N 1 +ATOM 29712 C CA . LEU P 1 154 ? 11.317 52.478 28.072 1.00 171.76 ? 154 LEU P CA 1 +ATOM 29713 C C . LEU P 1 154 ? 12.265 51.403 27.532 1.00 163.31 ? 154 LEU P C 1 +ATOM 29714 O O . LEU P 1 154 ? 13.070 51.651 26.614 1.00 92.80 ? 154 LEU P O 1 +ATOM 29715 C CB . LEU P 1 154 ? 10.016 52.496 27.263 1.00 143.31 ? 154 LEU P CB 1 +ATOM 29716 C CG . LEU P 1 154 ? 10.183 52.659 25.747 1.00 196.71 ? 154 LEU P CG 1 +ATOM 29717 C CD1 . LEU P 1 154 ? 10.194 51.312 25.038 1.00 194.09 ? 154 LEU P CD1 1 +ATOM 29718 C CD2 . LEU P 1 154 ? 9.080 53.552 25.205 1.00 248.46 ? 154 LEU P CD2 1 +ATOM 29719 N N . ASP P 1 155 ? 12.070 50.201 28.072 1.00 149.13 ? 155 ASP P N 1 +ATOM 29720 C CA . ASP P 1 155 ? 12.970 49.072 27.907 1.00 119.37 ? 155 ASP P CA 1 +ATOM 29721 C C . ASP P 1 155 ? 12.195 47.915 27.324 1.00 92.10 ? 155 ASP P C 1 +ATOM 29722 O O . ASP P 1 155 ? 10.955 47.904 27.383 1.00 98.36 ? 155 ASP P O 1 +ATOM 29723 C CB . ASP P 1 155 ? 13.534 48.662 29.271 1.00 135.99 ? 155 ASP P CB 1 +ATOM 29724 C CG . ASP P 1 155 ? 14.050 49.850 30.081 1.00 174.41 ? 155 ASP P CG 1 +ATOM 29725 O OD1 . ASP P 1 155 ? 13.226 50.552 30.714 1.00 156.41 ? 155 ASP P OD1 1 +ATOM 29726 O OD2 . ASP P 1 155 ? 15.286 50.071 30.097 1.00 209.36 ? 155 ASP P OD2 1 +ATOM 29727 N N . GLN P 1 156 ? 12.900 46.948 26.743 1.00 99.85 ? 156 GLN P N 1 +ATOM 29728 C CA . GLN P 1 156 ? 12.224 45.774 26.143 1.00 150.63 ? 156 GLN P CA 1 +ATOM 29729 C C . GLN P 1 156 ? 12.606 44.459 26.820 1.00 156.73 ? 156 GLN P C 1 +ATOM 29730 O O . GLN P 1 156 ? 13.607 44.385 27.519 1.00 191.01 ? 156 GLN P O 1 +ATOM 29731 C CB . GLN P 1 156 ? 12.563 45.662 24.665 1.00 162.57 ? 156 GLN P CB 1 +ATOM 29732 C CG . GLN P 1 156 ? 11.707 44.666 23.900 1.00 141.35 ? 156 GLN P CG 1 +ATOM 29733 C CD . GLN P 1 156 ? 11.733 44.916 22.406 1.00 132.05 ? 156 GLN P CD 1 +ATOM 29734 O OE1 . GLN P 1 156 ? 12.523 45.739 21.899 1.00 145.95 ? 156 GLN P OE1 1 +ATOM 29735 N NE2 . GLN P 1 156 ? 10.857 44.230 21.690 1.00 106.52 ? 156 GLN P NE2 1 +ATOM 29736 N N . ILE P 1 157 ? 11.728 43.470 26.719 1.00 119.52 ? 157 ILE P N 1 +ATOM 29737 C CA . ILE P 1 157 ? 11.971 42.178 27.327 1.00 119.51 ? 157 ILE P CA 1 +ATOM 29738 C C . ILE P 1 157 ? 11.239 41.160 26.470 1.00 150.50 ? 157 ILE P C 1 +ATOM 29739 O O . ILE P 1 157 ? 10.086 41.387 26.051 1.00 268.94 ? 157 ILE P O 1 +ATOM 29740 C CB . ILE P 1 157 ? 11.503 42.130 28.817 1.00 123.77 ? 157 ILE P CB 1 +ATOM 29741 C CG1 . ILE P 1 157 ? 12.252 41.045 29.582 1.00 129.07 ? 157 ILE P CG1 1 +ATOM 29742 C CG2 . ILE P 1 157 ? 9.996 41.888 28.933 1.00 118.21 ? 157 ILE P CG2 1 +ATOM 29743 C CD1 . ILE P 1 157 ? 12.001 41.044 31.084 1.00 125.74 ? 157 ILE P CD1 1 +ATOM 29744 N N . ALA P 1 158 ? 11.882 40.038 26.190 1.00 132.62 ? 158 ALA P N 1 +ATOM 29745 C CA . ALA P 1 158 ? 11.240 39.029 25.352 1.00 109.63 ? 158 ALA P CA 1 +ATOM 29746 C C . ALA P 1 158 ? 11.410 37.655 25.960 1.00 104.96 ? 158 ALA P C 1 +ATOM 29747 O O . ALA P 1 158 ? 12.346 37.396 26.722 1.00 68.72 ? 158 ALA P O 1 +ATOM 29748 C CB . ALA P 1 158 ? 11.796 39.069 23.943 1.00 92.47 ? 158 ALA P CB 1 +ATOM 29749 N N . VAL P 1 159 ? 10.450 36.792 25.661 1.00 108.99 ? 159 VAL P N 1 +ATOM 29750 C CA . VAL P 1 159 ? 10.413 35.476 26.272 1.00 118.41 ? 159 VAL P CA 1 +ATOM 29751 C C . VAL P 1 159 ? 10.073 34.430 25.227 1.00 120.51 ? 159 VAL P C 1 +ATOM 29752 O O . VAL P 1 159 ? 9.079 34.572 24.491 1.00 172.68 ? 159 VAL P O 1 +ATOM 29753 C CB . VAL P 1 159 ? 9.391 35.436 27.438 1.00 120.80 ? 159 VAL P CB 1 +ATOM 29754 C CG1 . VAL P 1 159 ? 8.966 34.012 27.753 1.00 117.38 ? 159 VAL P CG1 1 +ATOM 29755 C CG2 . VAL P 1 159 ? 9.991 36.083 28.679 1.00 126.42 ? 159 VAL P CG2 1 +ATOM 29756 N N . ASN P 1 160 ? 10.903 33.392 25.160 1.00 80.23 ? 160 ASN P N 1 +ATOM 29757 C CA . ASN P 1 160 ? 10.577 32.208 24.386 1.00 74.82 ? 160 ASN P CA 1 +ATOM 29758 C C . ASN P 1 160 ? 9.941 31.175 25.312 1.00 77.51 ? 160 ASN P C 1 +ATOM 29759 O O . ASN P 1 160 ? 10.452 30.899 26.417 1.00 87.34 ? 160 ASN P O 1 +ATOM 29760 C CB . ASN P 1 160 ? 11.851 31.659 23.767 1.00 62.72 ? 160 ASN P CB 1 +ATOM 29761 C CG . ASN P 1 160 ? 11.647 30.358 22.995 1.00 63.23 ? 160 ASN P CG 1 +ATOM 29762 O OD1 . ASN P 1 160 ? 11.014 29.391 23.476 1.00 63.01 ? 160 ASN P OD1 1 +ATOM 29763 N ND2 . ASN P 1 160 ? 12.306 30.267 21.844 1.00 51.46 ? 160 ASN P ND2 1 +ATOM 29764 N N . LEU P 1 161 ? 8.805 30.629 24.892 1.00 57.00 ? 161 LEU P N 1 +ATOM 29765 C CA . LEU P 1 161 ? 8.334 29.394 25.471 1.00 58.79 ? 161 LEU P CA 1 +ATOM 29766 C C . LEU P 1 161 ? 8.206 28.383 24.372 1.00 56.72 ? 161 LEU P C 1 +ATOM 29767 O O . LEU P 1 161 ? 7.760 28.712 23.274 1.00 89.22 ? 161 LEU P O 1 +ATOM 29768 C CB . LEU P 1 161 ? 7.003 29.612 26.208 1.00 64.35 ? 161 LEU P CB 1 +ATOM 29769 C CG . LEU P 1 161 ? 7.053 30.500 27.429 1.00 73.77 ? 161 LEU P CG 1 +ATOM 29770 C CD1 . LEU P 1 161 ? 5.652 30.795 27.941 1.00 86.50 ? 161 LEU P CD1 1 +ATOM 29771 C CD2 . LEU P 1 161 ? 7.894 29.841 28.519 1.00 80.54 ? 161 LEU P CD2 1 +ATOM 29772 N N . ARG P 1 162 ? 8.372 27.114 24.705 1.00 70.04 ? 162 ARG P N 1 +ATOM 29773 C CA . ARG P 1 162 ? 8.141 26.076 23.701 1.00 98.17 ? 162 ARG P CA 1 +ATOM 29774 C C . ARG P 1 162 ? 7.754 24.680 24.247 1.00 72.27 ? 162 ARG P C 1 +ATOM 29775 O O . ARG P 1 162 ? 8.337 24.190 25.192 1.00 79.82 ? 162 ARG P O 1 +ATOM 29776 C CB . ARG P 1 162 ? 9.362 25.989 22.785 1.00 115.03 ? 162 ARG P CB 1 +ATOM 29777 C CG . ARG P 1 162 ? 10.669 25.569 23.446 1.00 129.60 ? 162 ARG P CG 1 +ATOM 29778 C CD . ARG P 1 162 ? 11.669 25.139 22.375 1.00 127.46 ? 162 ARG P CD 1 +ATOM 29779 N NE . ARG P 1 162 ? 12.897 24.519 22.891 1.00 95.71 ? 162 ARG P NE 1 +ATOM 29780 C CZ . ARG P 1 162 ? 13.945 25.186 23.340 1.00 80.05 ? 162 ARG P CZ 1 +ATOM 29781 N NH1 . ARG P 1 162 ? 13.890 26.513 23.448 1.00 102.95 ? 162 ARG P NH1 1 +ATOM 29782 N NH2 . ARG P 1 162 ? 15.028 24.525 23.715 1.00 64.26 ? 162 ARG P NH2 1 +ATOM 29783 N N . VAL P 1 163 ? 6.745 24.083 23.624 1.00 61.56 ? 163 VAL P N 1 +ATOM 29784 C CA . VAL P 1 163 ? 6.234 22.786 24.008 1.00 57.28 ? 163 VAL P CA 1 +ATOM 29785 C C . VAL P 1 163 ? 7.065 21.787 23.290 1.00 52.25 ? 163 VAL P C 1 +ATOM 29786 O O . VAL P 1 163 ? 7.009 21.702 22.060 1.00 63.51 ? 163 VAL P O 1 +ATOM 29787 C CB . VAL P 1 163 ? 4.759 22.588 23.564 1.00 78.28 ? 163 VAL P CB 1 +ATOM 29788 C CG1 . VAL P 1 163 ? 4.278 21.187 23.928 1.00 75.10 ? 163 VAL P CG1 1 +ATOM 29789 C CG2 . VAL P 1 163 ? 3.851 23.669 24.184 1.00 112.18 ? 163 VAL P CG2 1 +ATOM 29790 N N . VAL P 1 164 ? 7.637 20.887 24.073 1.00 62.10 ? 164 VAL P N 1 +ATOM 29791 C CA . VAL P 1 164 ? 8.379 19.731 23.569 1.00 76.90 ? 164 VAL P CA 1 +ATOM 29792 C C . VAL P 1 164 ? 7.697 18.406 23.891 1.00 74.32 ? 164 VAL P C 1 +ATOM 29793 O O . VAL P 1 164 ? 7.140 18.233 24.970 1.00 58.86 ? 164 VAL P O 1 +ATOM 29794 C CB . VAL P 1 164 ? 9.741 19.633 24.221 1.00 67.68 ? 164 VAL P CB 1 +ATOM 29795 C CG1 . VAL P 1 164 ? 10.478 18.439 23.668 1.00 75.72 ? 164 VAL P CG1 1 +ATOM 29796 C CG2 . VAL P 1 164 ? 10.493 20.893 23.925 1.00 89.30 ? 164 VAL P CG2 1 +ATOM 29797 N N . ASN P 1 165 ? 7.598 17.549 22.874 1.00 78.97 ? 165 ASN P N 1 +ATOM 29798 C CA . ASN P 1 165 ? 6.895 16.279 23.012 1.00 84.75 ? 165 ASN P CA 1 +ATOM 29799 C C . ASN P 1 165 ? 7.872 15.259 23.590 1.00 84.85 ? 165 ASN P C 1 +ATOM 29800 O O . ASN P 1 165 ? 8.876 14.947 22.955 1.00 78.77 ? 165 ASN P O 1 +ATOM 29801 C CB . ASN P 1 165 ? 6.312 15.782 21.666 1.00 70.01 ? 165 ASN P CB 1 +ATOM 29802 C CG . ASN P 1 165 ? 5.373 14.610 21.853 1.00 74.56 ? 165 ASN P CG 1 +ATOM 29803 O OD1 . ASN P 1 165 ? 5.114 14.194 22.994 1.00 86.19 ? 165 ASN P OD1 1 +ATOM 29804 N ND2 . ASN P 1 165 ? 5.082 13.922 20.776 1.00 92.64 ? 165 ASN P ND2 1 +ATOM 29805 N N . VAL P 1 166 ? 7.535 14.724 24.762 1.00 75.78 ? 166 VAL P N 1 +ATOM 29806 C CA . VAL P 1 166 ? 8.403 13.804 25.479 1.00 60.46 ? 166 VAL P CA 1 +ATOM 29807 C C . VAL P 1 166 ? 8.610 12.580 24.673 1.00 49.93 ? 166 VAL P C 1 +ATOM 29808 O O . VAL P 1 166 ? 9.699 12.059 24.598 1.00 45.59 ? 166 VAL P O 1 +ATOM 29809 C CB . VAL P 1 166 ? 7.782 13.420 26.835 1.00 71.32 ? 166 VAL P CB 1 +ATOM 29810 C CG1 . VAL P 1 166 ? 8.285 12.066 27.307 1.00 62.79 ? 166 VAL P CG1 1 +ATOM 29811 C CG2 . VAL P 1 166 ? 8.043 14.543 27.875 1.00 79.55 ? 166 VAL P CG2 1 +ATOM 29812 N N . SER P 1 167 ? 7.554 12.153 24.012 1.00 64.68 ? 167 SER P N 1 +ATOM 29813 C CA . SER P 1 167 ? 7.574 10.893 23.288 1.00 92.17 ? 167 SER P CA 1 +ATOM 29814 C C . SER P 1 167 ? 8.470 10.905 22.044 1.00 75.33 ? 167 SER P C 1 +ATOM 29815 O O . SER P 1 167 ? 8.736 9.834 21.479 1.00 61.64 ? 167 SER P O 1 +ATOM 29816 C CB . SER P 1 167 ? 6.137 10.487 22.920 1.00 114.06 ? 167 SER P CB 1 +ATOM 29817 O OG . SER P 1 167 ? 5.274 10.675 24.026 1.00 151.85 ? 167 SER P OG 1 +ATOM 29818 N N . THR P 1 168 ? 8.907 12.090 21.609 1.00 63.38 ? 168 THR P N 1 +ATOM 29819 C CA . THR P 1 168 ? 9.659 12.203 20.357 1.00 72.92 ? 168 THR P CA 1 +ATOM 29820 C C . THR P 1 168 ? 10.812 13.187 20.406 1.00 54.50 ? 168 THR P C 1 +ATOM 29821 O O . THR P 1 168 ? 11.841 13.021 19.745 1.00 58.00 ? 168 THR P O 1 +ATOM 29822 C CB . THR P 1 168 ? 8.755 12.605 19.163 1.00 81.64 ? 168 THR P CB 1 +ATOM 29823 O OG1 . THR P 1 168 ? 8.003 13.772 19.495 1.00 104.69 ? 168 THR P OG1 1 +ATOM 29824 C CG2 . THR P 1 168 ? 7.792 11.461 18.762 1.00 76.24 ? 168 THR P CG2 1 +ATOM 29825 N N . GLY P 1 169 ? 10.624 14.242 21.145 1.00 50.01 ? 169 GLY P N 1 +ATOM 29826 C CA . GLY P 1 169 ? 11.601 15.283 21.107 1.00 68.07 ? 169 GLY P CA 1 +ATOM 29827 C C . GLY P 1 169 ? 11.329 16.285 20.011 1.00 88.53 ? 169 GLY P C 1 +ATOM 29828 O O . GLY P 1 169 ? 11.848 17.422 20.093 1.00 182.51 ? 169 GLY P O 1 +ATOM 29829 N N . GLU P 1 170 ? 10.369 15.996 19.127 1.00 78.00 ? 170 GLU P N 1 +ATOM 29830 C CA . GLU P 1 170 ? 9.699 17.082 18.358 1.00 101.19 ? 170 GLU P CA 1 +ATOM 29831 C C . GLU P 1 170 ? 9.214 18.262 19.239 1.00 80.00 ? 170 GLU P C 1 +ATOM 29832 O O . GLU P 1 170 ? 8.524 18.073 20.220 1.00 83.04 ? 170 GLU P O 1 +ATOM 29833 C CB . GLU P 1 170 ? 8.481 16.573 17.560 1.00 105.79 ? 170 GLU P CB 1 +ATOM 29834 C CG . GLU P 1 170 ? 8.857 15.709 16.362 1.00 119.59 ? 170 GLU P CG 1 +ATOM 29835 C CD . GLU P 1 170 ? 7.884 14.577 16.088 1.00 119.59 ? 170 GLU P CD 1 +ATOM 29836 O OE1 . GLU P 1 170 ? 7.039 14.283 16.969 1.00 138.30 ? 170 GLU P OE1 1 +ATOM 29837 O OE2 . GLU P 1 170 ? 8.052 13.885 15.060 1.00 124.27 ? 170 GLU P OE2 1 +ATOM 29838 N N . ILE P 1 171 ? 9.689 19.457 18.959 1.00 60.36 ? 171 ILE P N 1 +ATOM 29839 C CA . ILE P 1 171 ? 9.076 20.601 19.509 1.00 67.31 ? 171 ILE P CA 1 +ATOM 29840 C C . ILE P 1 171 ? 7.683 20.729 18.861 1.00 112.95 ? 171 ILE P C 1 +ATOM 29841 O O . ILE P 1 171 ? 7.554 20.783 17.628 1.00 192.33 ? 171 ILE P O 1 +ATOM 29842 C CB . ILE P 1 171 ? 9.924 21.819 19.230 1.00 59.37 ? 171 ILE P CB 1 +ATOM 29843 C CG1 . ILE P 1 171 ? 11.156 21.747 20.087 1.00 59.06 ? 171 ILE P CG1 1 +ATOM 29844 C CG2 . ILE P 1 171 ? 9.119 23.080 19.525 1.00 86.23 ? 171 ILE P CG2 1 +ATOM 29845 C CD1 . ILE P 1 171 ? 12.227 22.711 19.625 1.00 97.72 ? 171 ILE P CD1 1 +ATOM 29846 N N . LEU P 1 172 ? 6.638 20.828 19.677 1.00 131.23 ? 172 LEU P N 1 +ATOM 29847 C CA . LEU P 1 172 ? 5.274 20.925 19.154 1.00 116.40 ? 172 LEU P CA 1 +ATOM 29848 C C . LEU P 1 172 ? 4.767 22.374 18.987 1.00 105.40 ? 172 LEU P C 1 +ATOM 29849 O O . LEU P 1 172 ? 3.745 22.654 18.314 1.00 123.39 ? 172 LEU P O 1 +ATOM 29850 C CB . LEU P 1 172 ? 4.310 20.155 20.048 1.00 114.92 ? 172 LEU P CB 1 +ATOM 29851 C CG . LEU P 1 172 ? 4.505 18.620 19.997 1.00 141.76 ? 172 LEU P CG 1 +ATOM 29852 C CD1 . LEU P 1 172 ? 3.471 17.769 20.757 1.00 126.39 ? 172 LEU P CD1 1 +ATOM 29853 C CD2 . LEU P 1 172 ? 4.697 18.097 18.575 1.00 166.53 ? 172 LEU P CD2 1 +ATOM 29854 N N . SER P 1 173 ? 5.486 23.300 19.594 1.00 90.11 ? 173 SER P N 1 +ATOM 29855 C CA . SER P 1 173 ? 5.159 24.709 19.468 1.00 108.37 ? 173 SER P CA 1 +ATOM 29856 C C . SER P 1 173 ? 6.272 25.593 20.023 1.00 110.43 ? 173 SER P C 1 +ATOM 29857 O O . SER P 1 173 ? 6.759 25.365 21.131 1.00 178.60 ? 173 SER P O 1 +ATOM 29858 C CB . SER P 1 173 ? 3.880 25.000 20.239 1.00 120.34 ? 173 SER P CB 1 +ATOM 29859 O OG . SER P 1 173 ? 3.723 26.389 20.433 1.00 168.41 ? 173 SER P OG 1 +ATOM 29860 N N . SER P 1 174 ? 6.677 26.601 19.264 1.00 84.88 ? 174 SER P N 1 +ATOM 29861 C CA . SER P 1 174 ? 7.547 27.633 19.799 1.00 91.37 ? 174 SER P CA 1 +ATOM 29862 C C . SER P 1 174 ? 6.823 28.977 19.685 1.00 98.12 ? 174 SER P C 1 +ATOM 29863 O O . SER P 1 174 ? 6.245 29.285 18.645 1.00 157.51 ? 174 SER P O 1 +ATOM 29864 C CB . SER P 1 174 ? 8.903 27.663 19.050 1.00 69.32 ? 174 SER P CB 1 +ATOM 29865 O OG . SER P 1 174 ? 9.857 28.502 19.692 1.00 76.39 ? 174 SER P OG 1 +ATOM 29866 N N . VAL P 1 175 ? 6.894 29.794 20.735 1.00 74.36 ? 175 VAL P N 1 +ATOM 29867 C CA . VAL P 1 175 ? 6.328 31.132 20.713 1.00 76.83 ? 175 VAL P CA 1 +ATOM 29868 C C . VAL P 1 175 ? 7.274 32.167 21.290 1.00 77.46 ? 175 VAL P C 1 +ATOM 29869 O O . VAL P 1 175 ? 7.983 31.917 22.262 1.00 59.78 ? 175 VAL P O 1 +ATOM 29870 C CB . VAL P 1 175 ? 4.981 31.181 21.479 1.00 111.60 ? 175 VAL P CB 1 +ATOM 29871 C CG1 . VAL P 1 175 ? 3.953 30.273 20.808 1.00 132.36 ? 175 VAL P CG1 1 +ATOM 29872 C CG2 . VAL P 1 175 ? 5.158 30.756 22.916 1.00 118.04 ? 175 VAL P CG2 1 +ATOM 29873 N N . ASN P 1 176 ? 7.207 33.380 20.737 1.00 119.99 ? 176 ASN P N 1 +ATOM 29874 C CA . ASN P 1 176 ? 8.130 34.476 21.100 1.00 130.49 ? 176 ASN P CA 1 +ATOM 29875 C C . ASN P 1 176 ? 7.416 35.775 21.516 1.00 103.57 ? 176 ASN P C 1 +ATOM 29876 O O . ASN P 1 176 ? 7.095 36.577 20.659 1.00 99.27 ? 176 ASN P O 1 +ATOM 29877 C CB . ASN P 1 176 ? 9.040 34.760 19.888 1.00 119.63 ? 176 ASN P CB 1 +ATOM 29878 C CG . ASN P 1 176 ? 10.404 34.076 19.984 1.00 142.94 ? 176 ASN P CG 1 +ATOM 29879 O OD1 . ASN P 1 176 ? 11.358 34.357 19.203 1.00 107.61 ? 176 ASN P OD1 1 +ATOM 29880 N ND2 . ASN P 1 176 ? 10.501 33.145 20.934 1.00 150.74 ? 176 ASN P ND2 1 +ATOM 29881 N N . THR P 1 177 ? 7.174 35.980 22.816 1.00 94.09 ? 177 THR P N 1 +ATOM 29882 C CA . THR P 1 177 ? 6.419 37.156 23.291 1.00 84.36 ? 177 THR P CA 1 +ATOM 29883 C C . THR P 1 177 ? 7.366 38.265 23.716 1.00 111.50 ? 177 THR P C 1 +ATOM 29884 O O . THR P 1 177 ? 8.547 38.015 24.002 1.00 116.06 ? 177 THR P O 1 +ATOM 29885 C CB . THR P 1 177 ? 5.472 36.821 24.459 1.00 64.38 ? 177 THR P CB 1 +ATOM 29886 O OG1 . THR P 1 177 ? 6.242 36.496 25.618 1.00 77.43 ? 177 THR P OG1 1 +ATOM 29887 C CG2 . THR P 1 177 ? 4.590 35.620 24.109 1.00 62.65 ? 177 THR P CG2 1 +ATOM 29888 N N . SER P 1 178 ? 6.838 39.485 23.763 1.00 124.04 ? 178 SER P N 1 +ATOM 29889 C CA . SER P 1 178 ? 7.639 40.674 24.085 1.00 147.88 ? 178 SER P CA 1 +ATOM 29890 C C . SER P 1 178 ? 6.805 41.734 24.815 1.00 130.04 ? 178 SER P C 1 +ATOM 29891 O O . SER P 1 178 ? 5.598 41.777 24.707 1.00 83.00 ? 178 SER P O 1 +ATOM 29892 C CB . SER P 1 178 ? 8.223 41.314 22.822 1.00 142.82 ? 178 SER P CB 1 +ATOM 29893 O OG . SER P 1 178 ? 8.731 42.622 23.100 1.00 90.52 ? 178 SER P OG 1 +ATOM 29894 N N . LYS P 1 179 ? 7.480 42.575 25.586 1.00 138.57 ? 179 LYS P N 1 +ATOM 29895 C CA . LYS P 1 179 ? 6.785 43.477 26.484 1.00 101.22 ? 179 LYS P CA 1 +ATOM 29896 C C . LYS P 1 179 ? 7.700 44.648 26.814 1.00 122.53 ? 179 LYS P C 1 +ATOM 29897 O O . LYS P 1 179 ? 8.931 44.504 26.971 1.00 140.26 ? 179 LYS P O 1 +ATOM 29898 C CB . LYS P 1 179 ? 6.349 42.734 27.756 1.00 99.97 ? 179 LYS P CB 1 +ATOM 29899 C CG . LYS P 1 179 ? 5.015 43.165 28.310 1.00 73.62 ? 179 LYS P CG 1 +ATOM 29900 C CD . LYS P 1 179 ? 5.229 44.222 29.370 1.00 101.22 ? 179 LYS P CD 1 +ATOM 29901 C CE . LYS P 1 179 ? 3.902 44.800 29.818 1.00 118.02 ? 179 LYS P CE 1 +ATOM 29902 N NZ . LYS P 1 179 ? 4.083 46.042 30.617 1.00 130.02 ? 179 LYS P NZ 1 +ATOM 29903 N N . THR P 1 180 ? 7.084 45.810 26.942 1.00 129.25 ? 180 THR P N 1 +ATOM 29904 C CA . THR P 1 180 ? 7.819 47.042 27.159 1.00 146.92 ? 180 THR P CA 1 +ATOM 29905 C C . THR P 1 180 ? 7.653 47.551 28.602 1.00 161.12 ? 180 THR P C 1 +ATOM 29906 O O . THR P 1 180 ? 6.546 47.585 29.151 1.00 117.88 ? 180 THR P O 1 +ATOM 29907 C CB . THR P 1 180 ? 7.405 48.137 26.155 1.00 143.04 ? 180 THR P CB 1 +ATOM 29908 O OG1 . THR P 1 180 ? 7.692 49.425 26.705 1.00 143.66 ? 180 THR P OG1 1 +ATOM 29909 C CG2 . THR P 1 180 ? 5.927 48.033 25.818 1.00 140.49 ? 180 THR P CG2 1 +ATOM 29910 N N . ILE P 1 181 ? 8.778 47.896 29.220 1.00 169.97 ? 181 ILE P N 1 +ATOM 29911 C CA . ILE P 1 181 ? 8.774 48.422 30.571 1.00 146.73 ? 181 ILE P CA 1 +ATOM 29912 C C . ILE P 1 181 ? 8.835 49.954 30.510 1.00 161.45 ? 181 ILE P C 1 +ATOM 29913 O O . ILE P 1 181 ? 9.861 50.528 30.087 1.00 216.13 ? 181 ILE P O 1 +ATOM 29914 C CB . ILE P 1 181 ? 9.951 47.835 31.396 1.00 127.47 ? 181 ILE P CB 1 +ATOM 29915 C CG1 . ILE P 1 181 ? 9.930 46.314 31.337 1.00 93.07 ? 181 ILE P CG1 1 +ATOM 29916 C CG2 . ILE P 1 181 ? 9.879 48.262 32.857 1.00 148.48 ? 181 ILE P CG2 1 +ATOM 29917 C CD1 . ILE P 1 181 ? 11.180 45.740 30.729 1.00 116.40 ? 181 ILE P CD1 1 +ATOM 29918 N N . LEU P 1 182 ? 7.781 50.604 31.017 1.00 116.20 ? 182 LEU P N 1 +ATOM 29919 C CA . LEU P 1 182 ? 7.713 52.072 31.078 1.00 132.88 ? 182 LEU P CA 1 +ATOM 29920 C C . LEU P 1 182 ? 8.273 52.744 32.365 1.00 157.17 ? 182 LEU P C 1 +ATOM 29921 O O . LEU P 1 182 ? 8.031 52.286 33.490 1.00 142.34 ? 182 LEU P O 1 +ATOM 29922 C CB . LEU P 1 182 ? 6.274 52.502 30.916 1.00 105.80 ? 182 LEU P CB 1 +ATOM 29923 C CG . LEU P 1 182 ? 6.041 54.009 30.920 1.00 109.02 ? 182 LEU P CG 1 +ATOM 29924 C CD1 . LEU P 1 182 ? 6.750 54.746 29.777 1.00 96.41 ? 182 LEU P CD1 1 +ATOM 29925 C CD2 . LEU P 1 182 ? 4.545 54.241 30.879 1.00 129.02 ? 182 LEU P CD2 1 +ATOM 29926 N N . SER P 1 183 ? 9.007 53.848 32.180 1.00 162.87 ? 183 SER P N 1 +ATOM 29927 C CA . SER P 1 183 ? 9.491 54.669 33.291 1.00 150.76 ? 183 SER P CA 1 +ATOM 29928 C C . SER P 1 183 ? 9.349 56.155 32.961 1.00 169.32 ? 183 SER P C 1 +ATOM 29929 O O . SER P 1 183 ? 9.551 56.567 31.815 1.00 139.11 ? 183 SER P O 1 +ATOM 29930 C CB . SER P 1 183 ? 10.954 54.368 33.581 1.00 143.28 ? 183 SER P CB 1 +ATOM 29931 O OG . SER P 1 183 ? 11.226 52.994 33.430 1.00 159.14 ? 183 SER P OG 1 +ATOM 29932 N N . TYR P 1 184 ? 8.948 56.950 33.953 1.00 180.41 ? 184 TYR P N 1 +ATOM 29933 C CA . TYR P 1 184 ? 8.847 58.390 33.764 1.00 143.62 ? 184 TYR P CA 1 +ATOM 29934 C C . TYR P 1 184 ? 9.092 59.193 35.044 1.00 150.23 ? 184 TYR P C 1 +ATOM 29935 O O . TYR P 1 184 ? 8.828 58.742 36.170 1.00 90.49 ? 184 TYR P O 1 +ATOM 29936 C CB . TYR P 1 184 ? 7.507 58.767 33.111 1.00 130.44 ? 184 TYR P CB 1 +ATOM 29937 C CG . TYR P 1 184 ? 6.285 58.328 33.895 1.00 127.04 ? 184 TYR P CG 1 +ATOM 29938 C CD1 . TYR P 1 184 ? 5.763 59.122 34.902 1.00 152.38 ? 184 TYR P CD1 1 +ATOM 29939 C CD2 . TYR P 1 184 ? 5.632 57.141 33.597 1.00 114.10 ? 184 TYR P CD2 1 +ATOM 29940 C CE1 . TYR P 1 184 ? 4.636 58.736 35.598 1.00 149.03 ? 184 TYR P CE1 1 +ATOM 29941 C CE2 . TYR P 1 184 ? 4.495 56.753 34.275 1.00 113.37 ? 184 TYR P CE2 1 +ATOM 29942 C CZ . TYR P 1 184 ? 4.009 57.548 35.280 1.00 140.48 ? 184 TYR P CZ 1 +ATOM 29943 O OH . TYR P 1 184 ? 2.906 57.144 35.987 1.00 178.28 ? 184 TYR P OH 1 +ATOM 29944 N N . GLU P 1 185 ? 9.535 60.427 34.831 1.00 182.86 ? 185 GLU P N 1 +ATOM 29945 C CA . GLU P 1 185 ? 9.833 61.375 35.904 1.00 205.52 ? 185 GLU P CA 1 +ATOM 29946 C C . GLU P 1 185 ? 9.216 62.748 35.629 1.00 211.90 ? 185 GLU P C 1 +ATOM 29947 O O . GLU P 1 185 ? 9.628 63.438 34.705 1.00 191.55 ? 185 GLU P O 1 +ATOM 29948 C CB . GLU P 1 185 ? 11.337 61.556 36.099 1.00 174.11 ? 185 GLU P CB 1 +ATOM 29949 C CG . GLU P 1 185 ? 12.167 60.295 36.020 1.00 144.06 ? 185 GLU P CG 1 +ATOM 29950 C CD . GLU P 1 185 ? 13.597 60.563 36.433 1.00 169.69 ? 185 GLU P CD 1 +ATOM 29951 O OE1 . GLU P 1 185 ? 13.939 61.744 36.719 1.00 203.32 ? 185 GLU P OE1 1 +ATOM 29952 O OE2 . GLU P 1 185 ? 14.381 59.599 36.481 1.00 205.19 ? 185 GLU P OE2 1 +ATOM 29953 N N . VAL P 1 186 ? 8.241 63.128 36.449 1.00 183.28 ? 186 VAL P N 1 +ATOM 29954 C CA . VAL P 1 186 ? 7.605 64.426 36.366 1.00 174.28 ? 186 VAL P CA 1 +ATOM 29955 C C . VAL P 1 186 ? 8.163 65.335 37.459 1.00 199.15 ? 186 VAL P C 1 +ATOM 29956 O O . VAL P 1 186 ? 8.352 64.904 38.594 1.00 191.07 ? 186 VAL P O 1 +ATOM 29957 C CB . VAL P 1 186 ? 6.075 64.299 36.510 1.00 156.85 ? 186 VAL P CB 1 +ATOM 29958 C CG1 . VAL P 1 186 ? 5.405 65.628 36.216 1.00 156.41 ? 186 VAL P CG1 1 +ATOM 29959 C CG2 . VAL P 1 186 ? 5.540 63.225 35.574 1.00 160.11 ? 186 VAL P CG2 1 +ATOM 29960 N N . GLN P 1 187 ? 8.422 66.593 37.109 1.00 209.49 ? 187 GLN P N 1 +ATOM 29961 C CA . GLN P 1 187 ? 9.011 67.540 38.053 1.00 179.29 ? 187 GLN P CA 1 +ATOM 29962 C C . GLN P 1 187 ? 8.512 68.948 37.799 1.00 170.84 ? 187 GLN P C 1 +ATOM 29963 O O . GLN P 1 187 ? 8.430 69.387 36.649 1.00 147.92 ? 187 GLN P O 1 +ATOM 29964 C CB . GLN P 1 187 ? 10.533 67.520 37.912 1.00 161.78 ? 187 GLN P CB 1 +ATOM 29965 C CG . GLN P 1 187 ? 11.238 66.451 38.720 1.00 174.22 ? 187 GLN P CG 1 +ATOM 29966 C CD . GLN P 1 187 ? 12.620 66.149 38.180 1.00 204.99 ? 187 GLN P CD 1 +ATOM 29967 O OE1 . GLN P 1 187 ? 13.328 67.053 37.731 1.00 209.46 ? 187 GLN P OE1 1 +ATOM 29968 N NE2 . GLN P 1 187 ? 13.006 64.865 38.192 1.00 204.29 ? 187 GLN P NE2 1 +ATOM 29969 N N . ALA P 1 188 ? 8.218 69.668 38.874 1.00 178.46 ? 188 ALA P N 1 +ATOM 29970 C CA . ALA P 1 188 ? 7.825 71.068 38.762 1.00 195.61 ? 188 ALA P CA 1 +ATOM 29971 C C . ALA P 1 188 ? 8.440 71.895 39.888 1.00 205.43 ? 188 ALA P C 1 +ATOM 29972 O O . ALA P 1 188 ? 8.533 71.428 41.013 1.00 191.19 ? 188 ALA P O 1 +ATOM 29973 C CB . ALA P 1 188 ? 6.311 71.185 38.762 1.00 166.67 ? 188 ALA P CB 1 +ATOM 29974 N N . GLY P 1 189 ? 8.900 73.103 39.567 1.00 185.02 ? 189 GLY P N 1 +ATOM 29975 C CA . GLY P 1 189 ? 9.549 73.967 40.545 1.00 179.19 ? 189 GLY P CA 1 +ATOM 29976 C C . GLY P 1 189 ? 9.242 75.439 40.343 1.00 189.95 ? 189 GLY P C 1 +ATOM 29977 O O . GLY P 1 189 ? 9.198 75.921 39.215 1.00 201.43 ? 189 GLY P O 1 +ATOM 29978 N N . VAL P 1 190 ? 8.988 76.147 41.441 1.00 223.16 ? 190 VAL P N 1 +ATOM 29979 C CA . VAL P 1 190 ? 8.712 77.579 41.397 1.00 220.00 ? 190 VAL P CA 1 +ATOM 29980 C C . VAL P 1 190 ? 9.833 78.337 42.117 1.00 212.69 ? 190 VAL P C 1 +ATOM 29981 O O . VAL P 1 190 ? 10.268 77.936 43.205 1.00 242.11 ? 190 VAL P O 1 +ATOM 29982 C CB . VAL P 1 190 ? 7.347 77.910 42.042 1.00 211.47 ? 190 VAL P CB 1 +ATOM 29983 C CG1 . VAL P 1 190 ? 6.970 79.355 41.761 1.00 216.84 ? 190 VAL P CG1 1 +ATOM 29984 C CG2 . VAL P 1 190 ? 6.263 76.959 41.540 1.00 188.23 ? 190 VAL P CG2 1 +ATOM 29985 N N . PHE P 1 191 ? 10.309 79.420 41.506 1.00 185.86 ? 191 PHE P N 1 +ATOM 29986 C CA . PHE P 1 191 ? 11.496 80.119 42.006 1.00 197.02 ? 191 PHE P CA 1 +ATOM 29987 C C . PHE P 1 191 ? 11.252 81.626 42.063 1.00 184.72 ? 191 PHE P C 1 +ATOM 29988 O O . PHE P 1 191 ? 10.775 82.210 41.087 1.00 229.81 ? 191 PHE P O 1 +ATOM 29989 C CB . PHE P 1 191 ? 12.702 79.792 41.111 1.00 187.40 ? 191 PHE P CB 1 +ATOM 29990 C CG . PHE P 1 191 ? 14.036 80.019 41.770 1.00 224.02 ? 191 PHE P CG 1 +ATOM 29991 C CD1 . PHE P 1 191 ? 14.505 81.307 41.996 1.00 223.11 ? 191 PHE P CD1 1 +ATOM 29992 C CD2 . PHE P 1 191 ? 14.830 78.945 42.157 1.00 220.22 ? 191 PHE P CD2 1 +ATOM 29993 C CE1 . PHE P 1 191 ? 15.735 81.521 42.599 1.00 194.92 ? 191 PHE P CE1 1 +ATOM 29994 C CE2 . PHE P 1 191 ? 16.053 79.152 42.772 1.00 204.85 ? 191 PHE P CE2 1 +ATOM 29995 C CZ . PHE P 1 191 ? 16.511 80.443 42.984 1.00 182.95 ? 191 PHE P CZ 1 +ATOM 29996 N N . LEU P 1 200 ? 12.005 82.831 47.565 1.00 227.11 ? 200 LEU P N 1 +ATOM 29997 C CA . LEU P 1 200 ? 11.062 81.720 47.462 1.00 201.88 ? 200 LEU P CA 1 +ATOM 29998 C C . LEU P 1 200 ? 11.515 80.691 46.435 1.00 205.41 ? 200 LEU P C 1 +ATOM 29999 O O . LEU P 1 200 ? 11.563 80.982 45.236 1.00 142.07 ? 200 LEU P O 1 +ATOM 30000 C CB . LEU P 1 200 ? 9.674 82.227 47.071 1.00 177.28 ? 200 LEU P CB 1 +ATOM 30001 C CG . LEU P 1 200 ? 8.665 81.116 46.731 1.00 160.67 ? 200 LEU P CG 1 +ATOM 30002 C CD1 . LEU P 1 200 ? 7.731 80.873 47.909 1.00 137.17 ? 200 LEU P CD1 1 +ATOM 30003 C CD2 . LEU P 1 200 ? 7.889 81.401 45.443 1.00 149.35 ? 200 LEU P CD2 1 +ATOM 30004 N N . GLU P 1 201 ? 11.824 79.487 46.917 1.00 214.76 ? 201 GLU P N 1 +ATOM 30005 C CA . GLU P 1 201 ? 11.887 78.308 46.066 1.00 206.79 ? 201 GLU P CA 1 +ATOM 30006 C C . GLU P 1 201 ? 10.891 77.256 46.543 1.00 203.32 ? 201 GLU P C 1 +ATOM 30007 O O . GLU P 1 201 ? 10.618 77.148 47.737 1.00 195.97 ? 201 GLU P O 1 +ATOM 30008 C CB . GLU P 1 201 ? 13.294 77.715 46.056 1.00 203.81 ? 201 GLU P CB 1 +ATOM 30009 C CG . GLU P 1 201 ? 13.543 76.808 44.863 1.00 214.39 ? 201 GLU P CG 1 +ATOM 30010 C CD . GLU P 1 201 ? 14.941 76.213 44.843 1.00 219.40 ? 201 GLU P CD 1 +ATOM 30011 O OE1 . GLU P 1 201 ? 15.922 76.976 44.975 1.00 202.32 ? 201 GLU P OE1 1 +ATOM 30012 O OE2 . GLU P 1 201 ? 15.056 74.978 44.674 1.00 213.80 ? 201 GLU P OE2 1 +ATOM 30013 N N . GLY P 1 202 ? 10.345 76.491 45.602 1.00 203.02 ? 202 GLY P N 1 +ATOM 30014 C CA . GLY P 1 202 ? 9.488 75.352 45.924 1.00 196.66 ? 202 GLY P CA 1 +ATOM 30015 C C . GLY P 1 202 ? 9.530 74.314 44.816 1.00 189.08 ? 202 GLY P C 1 +ATOM 30016 O O . GLY P 1 202 ? 9.256 74.639 43.661 1.00 243.79 ? 202 GLY P O 1 +ATOM 30017 N N . GLU P 1 203 ? 9.818 73.061 45.165 1.00 161.54 ? 203 GLU P N 1 +ATOM 30018 C CA . GLU P 1 203 ? 9.863 71.988 44.162 1.00 149.01 ? 203 GLU P CA 1 +ATOM 30019 C C . GLU P 1 203 ? 8.958 70.772 44.539 1.00 161.16 ? 203 GLU P C 1 +ATOM 30020 O O . GLU P 1 203 ? 8.867 70.348 45.705 1.00 134.57 ? 203 GLU P O 1 +ATOM 30021 C CB . GLU P 1 203 ? 11.336 71.575 43.849 1.00 144.99 ? 203 GLU P CB 1 +ATOM 30022 C CG . GLU P 1 203 ? 11.495 70.245 43.090 1.00 154.80 ? 203 GLU P CG 1 +ATOM 30023 C CD . GLU P 1 203 ? 12.911 69.657 43.102 1.00 146.32 ? 203 GLU P CD 1 +ATOM 30024 O OE1 . GLU P 1 203 ? 13.859 70.364 43.519 1.00 184.68 ? 203 GLU P OE1 1 +ATOM 30025 O OE2 . GLU P 1 203 ? 13.083 68.485 42.661 1.00 104.89 ? 203 GLU P OE2 1 +ATOM 30026 N N . VAL P 1 204 ? 8.267 70.245 43.526 1.00 176.66 ? 204 VAL P N 1 +ATOM 30027 C CA . VAL P 1 204 ? 7.559 68.961 43.599 1.00 184.21 ? 204 VAL P CA 1 +ATOM 30028 C C . VAL P 1 204 ? 8.100 68.017 42.517 1.00 197.73 ? 204 VAL P C 1 +ATOM 30029 O O . VAL P 1 204 ? 8.340 68.437 41.384 1.00 146.14 ? 204 VAL P O 1 +ATOM 30030 C CB . VAL P 1 204 ? 6.035 69.145 43.422 1.00 156.39 ? 204 VAL P CB 1 +ATOM 30031 C CG1 . VAL P 1 204 ? 5.336 67.820 43.124 1.00 146.79 ? 204 VAL P CG1 1 +ATOM 30032 C CG2 . VAL P 1 204 ? 5.447 69.784 44.667 1.00 145.40 ? 204 VAL P CG2 1 +ATOM 30033 N N . GLY P 1 205 ? 8.350 66.765 42.901 1.00 197.45 ? 205 GLY P N 1 +ATOM 30034 C CA . GLY P 1 205 ? 8.813 65.748 41.967 1.00 156.06 ? 205 GLY P CA 1 +ATOM 30035 C C . GLY P 1 205 ? 8.100 64.418 42.156 1.00 151.29 ? 205 GLY P C 1 +ATOM 30036 O O . GLY P 1 205 ? 7.659 64.087 43.260 1.00 136.43 ? 205 GLY P O 1 +ATOM 30037 N N . TYR P 1 206 ? 7.965 63.662 41.069 1.00 146.96 ? 206 TYR P N 1 +ATOM 30038 C CA . TYR P 1 206 ? 7.394 62.309 41.112 1.00 138.05 ? 206 TYR P CA 1 +ATOM 30039 C C . TYR P 1 206 ? 8.032 61.426 40.044 1.00 138.12 ? 206 TYR P C 1 +ATOM 30040 O O . TYR P 1 206 ? 8.296 61.887 38.948 1.00 125.07 ? 206 TYR P O 1 +ATOM 30041 C CB . TYR P 1 206 ? 5.883 62.347 40.885 1.00 116.28 ? 206 TYR P CB 1 +ATOM 30042 C CG . TYR P 1 206 ? 5.229 60.981 40.845 1.00 91.36 ? 206 TYR P CG 1 +ATOM 30043 C CD1 . TYR P 1 206 ? 4.930 60.297 42.025 1.00 92.40 ? 206 TYR P CD1 1 +ATOM 30044 C CD2 . TYR P 1 206 ? 4.871 60.389 39.629 1.00 75.15 ? 206 TYR P CD2 1 +ATOM 30045 C CE1 . TYR P 1 206 ? 4.296 59.059 41.994 1.00 96.79 ? 206 TYR P CE1 1 +ATOM 30046 C CE2 . TYR P 1 206 ? 4.225 59.165 39.583 1.00 74.34 ? 206 TYR P CE2 1 +ATOM 30047 C CZ . TYR P 1 206 ? 3.952 58.491 40.763 1.00 96.67 ? 206 TYR P CZ 1 +ATOM 30048 O OH . TYR P 1 206 ? 3.383 57.232 40.710 1.00 93.57 ? 206 TYR P OH 1 +ATOM 30049 N N . THR P 1 207 ? 8.298 60.162 40.374 1.00 133.66 ? 207 THR P N 1 +ATOM 30050 C CA . THR P 1 207 ? 8.889 59.220 39.415 1.00 118.28 ? 207 THR P CA 1 +ATOM 30051 C C . THR P 1 207 ? 8.203 57.852 39.508 1.00 132.02 ? 207 THR P C 1 +ATOM 30052 O O . THR P 1 207 ? 7.936 57.343 40.611 1.00 109.72 ? 207 THR P O 1 +ATOM 30053 C CB . THR P 1 207 ? 10.407 59.039 39.642 1.00 97.12 ? 207 THR P CB 1 +ATOM 30054 O OG1 . THR P 1 207 ? 10.628 58.491 40.947 1.00 124.81 ? 207 THR P OG1 1 +ATOM 30055 C CG2 . THR P 1 207 ? 11.132 60.347 39.532 1.00 80.20 ? 207 THR P CG2 1 +ATOM 30056 N N . SER P 1 208 ? 7.910 57.254 38.355 1.00 146.67 ? 208 SER P N 1 +ATOM 30057 C CA . SER P 1 208 ? 7.282 55.927 38.334 1.00 170.15 ? 208 SER P CA 1 +ATOM 30058 C C . SER P 1 208 ? 7.962 54.967 37.356 1.00 201.75 ? 208 SER P C 1 +ATOM 30059 O O . SER P 1 208 ? 8.114 55.274 36.174 1.00 153.71 ? 208 SER P O 1 +ATOM 30060 C CB . SER P 1 208 ? 5.795 56.030 38.003 1.00 169.32 ? 208 SER P CB 1 +ATOM 30061 O OG . SER P 1 208 ? 5.222 54.736 37.850 1.00 125.29 ? 208 SER P OG 1 +ATOM 30062 N N . ASN P 1 209 ? 8.364 53.808 37.876 1.00 209.43 ? 209 ASN P N 1 +ATOM 30063 C CA . ASN P 1 209 ? 8.908 52.716 37.071 1.00 149.64 ? 209 ASN P CA 1 +ATOM 30064 C C . ASN P 1 209 ? 7.973 51.536 37.100 1.00 179.74 ? 209 ASN P C 1 +ATOM 30065 O O . ASN P 1 209 ? 7.451 51.170 38.153 1.00 202.33 ? 209 ASN P O 1 +ATOM 30066 C CB . ASN P 1 209 ? 10.241 52.260 37.623 1.00 112.39 ? 209 ASN P CB 1 +ATOM 30067 C CG . ASN P 1 209 ? 11.312 53.287 37.416 1.00 97.93 ? 209 ASN P CG 1 +ATOM 30068 O OD1 . ASN P 1 209 ? 11.933 53.343 36.368 1.00 70.02 ? 209 ASN P OD1 1 +ATOM 30069 N ND2 . ASN P 1 209 ? 11.595 54.055 38.458 1.00 112.15 ? 209 ASN P ND2 1 +ATOM 30070 N N . GLU P 1 210 ? 7.758 50.936 35.940 1.00 180.12 ? 210 GLU P N 1 +ATOM 30071 C CA . GLU P 1 210 ? 7.093 49.646 35.903 1.00 139.74 ? 210 GLU P CA 1 +ATOM 30072 C C . GLU P 1 210 ? 8.023 48.635 36.556 1.00 98.49 ? 210 GLU P C 1 +ATOM 30073 O O . GLU P 1 210 ? 9.244 48.673 36.357 1.00 113.53 ? 210 GLU P O 1 +ATOM 30074 C CB . GLU P 1 210 ? 6.785 49.250 34.451 1.00 192.44 ? 210 GLU P CB 1 +ATOM 30075 C CG . GLU P 1 210 ? 5.398 48.672 34.222 1.00 192.48 ? 210 GLU P CG 1 +ATOM 30076 C CD . GLU P 1 210 ? 4.988 48.700 32.749 1.00 193.04 ? 210 GLU P CD 1 +ATOM 30077 O OE1 . GLU P 1 210 ? 5.482 49.557 31.958 1.00 111.23 ? 210 GLU P OE1 1 +ATOM 30078 O OE2 . GLU P 1 210 ? 4.162 47.837 32.388 1.00 216.31 ? 210 GLU P OE2 1 +ATOM 30079 N N . PRO P 1 211 ? 7.461 47.702 37.303 1.00 80.55 ? 211 PRO P N 1 +ATOM 30080 C CA . PRO P 1 211 ? 8.260 46.579 37.750 1.00 99.52 ? 211 PRO P CA 1 +ATOM 30081 C C . PRO P 1 211 ? 8.616 45.591 36.626 1.00 110.50 ? 211 PRO P C 1 +ATOM 30082 O O . PRO P 1 211 ? 7.734 45.092 35.933 1.00 83.71 ? 211 PRO P O 1 +ATOM 30083 C CB . PRO P 1 211 ? 7.371 45.900 38.796 1.00 95.85 ? 211 PRO P CB 1 +ATOM 30084 C CG . PRO P 1 211 ? 6.349 46.908 39.143 1.00 108.23 ? 211 PRO P CG 1 +ATOM 30085 C CD . PRO P 1 211 ? 6.123 47.670 37.873 1.00 103.00 ? 211 PRO P CD 1 +ATOM 30086 N N . VAL P 1 212 ? 9.920 45.348 36.441 1.00 125.71 ? 212 VAL P N 1 +ATOM 30087 C CA . VAL P 1 212 ? 10.423 44.410 35.432 1.00 90.99 ? 212 VAL P CA 1 +ATOM 30088 C C . VAL P 1 212 ? 9.939 43.003 35.771 1.00 80.36 ? 212 VAL P C 1 +ATOM 30089 O O . VAL P 1 212 ? 9.478 42.254 34.906 1.00 98.10 ? 212 VAL P O 1 +ATOM 30090 C CB . VAL P 1 212 ? 11.962 44.385 35.390 1.00 87.05 ? 212 VAL P CB 1 +ATOM 30091 C CG1 . VAL P 1 212 ? 12.434 43.498 34.247 1.00 120.23 ? 212 VAL P CG1 1 +ATOM 30092 C CG2 . VAL P 1 212 ? 12.540 45.792 35.253 1.00 76.92 ? 212 VAL P CG2 1 +ATOM 30093 N N . MET P 1 213 ? 10.018 42.692 37.050 1.00 70.23 ? 213 MET P N 1 +ATOM 30094 C CA . MET P 1 213 ? 9.293 41.607 37.674 1.00 102.57 ? 213 MET P CA 1 +ATOM 30095 C C . MET P 1 213 ? 7.898 41.327 37.053 1.00 133.12 ? 213 MET P C 1 +ATOM 30096 O O . MET P 1 213 ? 7.551 40.180 36.698 1.00 169.16 ? 213 MET P O 1 +ATOM 30097 C CB . MET P 1 213 ? 9.161 42.012 39.155 1.00 109.90 ? 213 MET P CB 1 +ATOM 30098 C CG . MET P 1 213 ? 8.570 41.013 40.122 1.00 133.78 ? 213 MET P CG 1 +ATOM 30099 S SD . MET P 1 213 ? 8.602 41.761 41.759 1.00 113.09 ? 213 MET P SD 1 +ATOM 30100 C CE . MET P 1 213 ? 6.831 42.006 41.905 1.00 162.39 ? 213 MET P CE 1 +ATOM 30101 N N . LEU P 1 214 ? 7.094 42.378 36.958 1.00 132.12 ? 214 LEU P N 1 +ATOM 30102 C CA . LEU P 1 214 ? 5.666 42.246 36.701 1.00 123.06 ? 214 LEU P CA 1 +ATOM 30103 C C . LEU P 1 214 ? 5.456 42.128 35.198 1.00 83.29 ? 214 LEU P C 1 +ATOM 30104 O O . LEU P 1 214 ? 4.498 41.509 34.733 1.00 92.65 ? 214 LEU P O 1 +ATOM 30105 C CB . LEU P 1 214 ? 4.915 43.462 37.276 1.00 132.45 ? 214 LEU P CB 1 +ATOM 30106 C CG . LEU P 1 214 ? 3.575 43.242 38.003 1.00 136.41 ? 214 LEU P CG 1 +ATOM 30107 C CD1 . LEU P 1 214 ? 3.719 42.332 39.217 1.00 122.28 ? 214 LEU P CD1 1 +ATOM 30108 C CD2 . LEU P 1 214 ? 2.993 44.590 38.412 1.00 144.99 ? 214 LEU P CD2 1 +ATOM 30109 N N . CYS P 1 215 ? 6.344 42.755 34.445 1.00 58.85 ? 215 CYS P N 1 +ATOM 30110 C CA . CYS P 1 215 ? 6.313 42.670 32.989 1.00 71.28 ? 215 CYS P CA 1 +ATOM 30111 C C . CYS P 1 215 ? 6.691 41.254 32.530 1.00 96.34 ? 215 CYS P C 1 +ATOM 30112 O O . CYS P 1 215 ? 6.138 40.709 31.547 1.00 96.58 ? 215 CYS P O 1 +ATOM 30113 C CB . CYS P 1 215 ? 7.289 43.677 32.369 1.00 66.66 ? 215 CYS P CB 1 +ATOM 30114 S SG . CYS P 1 215 ? 6.846 45.371 32.699 1.00 110.82 ? 215 CYS P SG 1 +ATOM 30115 N N . LEU P 1 216 ? 7.713 40.705 33.188 1.00 119.33 ? 216 LEU P N 1 +ATOM 30116 C CA . LEU P 1 216 ? 8.140 39.346 32.922 1.00 100.48 ? 216 LEU P CA 1 +ATOM 30117 C C . LEU P 1 216 ? 6.929 38.420 33.128 1.00 90.71 ? 216 LEU P C 1 +ATOM 30118 O O . LEU P 1 216 ? 6.634 37.588 32.262 1.00 104.60 ? 216 LEU P O 1 +ATOM 30119 C CB . LEU P 1 216 ? 9.325 38.957 33.830 1.00 71.26 ? 216 LEU P CB 1 +ATOM 30120 C CG . LEU P 1 216 ? 9.802 37.518 33.667 1.00 65.08 ? 216 LEU P CG 1 +ATOM 30121 C CD1 . LEU P 1 216 ? 10.243 37.184 32.235 1.00 71.75 ? 216 LEU P CD1 1 +ATOM 30122 C CD2 . LEU P 1 216 ? 10.940 37.240 34.603 1.00 67.99 ? 216 LEU P CD2 1 +ATOM 30123 N N . MET P 1 217 ? 6.230 38.603 34.246 1.00 63.67 ? 217 MET P N 1 +ATOM 30124 C CA . MET P 1 217 ? 5.153 37.714 34.601 1.00 51.37 ? 217 MET P CA 1 +ATOM 30125 C C . MET P 1 217 ? 4.068 37.826 33.566 1.00 65.18 ? 217 MET P C 1 +ATOM 30126 O O . MET P 1 217 ? 3.561 36.821 33.068 1.00 69.92 ? 217 MET P O 1 +ATOM 30127 C CB . MET P 1 217 ? 4.634 38.061 35.972 1.00 57.03 ? 217 MET P CB 1 +ATOM 30128 C CG . MET P 1 217 ? 4.345 36.836 36.821 1.00 76.78 ? 217 MET P CG 1 +ATOM 30129 S SD . MET P 1 217 ? 2.917 35.899 36.231 1.00 115.77 ? 217 MET P SD 1 +ATOM 30130 C CE . MET P 1 217 ? 2.982 34.398 37.220 1.00 122.74 ? 217 MET P CE 1 +ATOM 30131 N N . SER P 1 218 ? 3.730 39.066 33.186 1.00 110.13 ? 218 SER P N 1 +ATOM 30132 C CA . SER P 1 218 ? 2.679 39.353 32.162 1.00 95.22 ? 218 SER P CA 1 +ATOM 30133 C C . SER P 1 218 ? 2.983 38.692 30.824 1.00 95.51 ? 218 SER P C 1 +ATOM 30134 O O . SER P 1 218 ? 2.151 37.934 30.293 1.00 98.17 ? 218 SER P O 1 +ATOM 30135 C CB . SER P 1 218 ? 2.562 40.849 31.927 1.00 74.77 ? 218 SER P CB 1 +ATOM 30136 O OG . SER P 1 218 ? 1.444 41.137 31.142 1.00 80.01 ? 218 SER P OG 1 +ATOM 30137 N N . ALA P 1 219 ? 4.218 38.876 30.355 1.00 94.98 ? 219 ALA P N 1 +ATOM 30138 C CA . ALA P 1 219 ? 4.648 38.280 29.096 1.00 115.00 ? 219 ALA P CA 1 +ATOM 30139 C C . ALA P 1 219 ? 4.632 36.716 29.092 1.00 103.83 ? 219 ALA P C 1 +ATOM 30140 O O . ALA P 1 219 ? 4.271 36.084 28.081 1.00 68.88 ? 219 ALA P O 1 +ATOM 30141 C CB . ALA P 1 219 ? 6.027 38.799 28.734 1.00 108.89 ? 219 ALA P CB 1 +ATOM 30142 N N . ILE P 1 220 ? 4.987 36.105 30.221 1.00 74.51 ? 220 ILE P N 1 +ATOM 30143 C CA . ILE P 1 220 ? 4.937 34.660 30.330 1.00 77.48 ? 220 ILE P CA 1 +ATOM 30144 C C . ILE P 1 220 ? 3.496 34.132 30.261 1.00 112.13 ? 220 ILE P C 1 +ATOM 30145 O O . ILE P 1 220 ? 3.214 33.131 29.595 1.00 126.34 ? 220 ILE P O 1 +ATOM 30146 C CB . ILE P 1 220 ? 5.598 34.182 31.621 1.00 80.27 ? 220 ILE P CB 1 +ATOM 30147 C CG1 . ILE P 1 220 ? 7.110 34.426 31.530 1.00 99.53 ? 220 ILE P CG1 1 +ATOM 30148 C CG2 . ILE P 1 220 ? 5.295 32.703 31.885 1.00 66.88 ? 220 ILE P CG2 1 +ATOM 30149 C CD1 . ILE P 1 220 ? 7.834 34.362 32.865 1.00 136.05 ? 220 ILE P CD1 1 +ATOM 30150 N N . GLU P 1 221 ? 2.569 34.824 30.920 1.00 169.82 ? 221 GLU P N 1 +ATOM 30151 C CA . GLU P 1 221 ? 1.132 34.478 30.844 1.00 167.55 ? 221 GLU P CA 1 +ATOM 30152 C C . GLU P 1 221 ? 0.635 34.505 29.397 1.00 130.30 ? 221 GLU P C 1 +ATOM 30153 O O . GLU P 1 221 ? 0.056 33.529 28.904 1.00 101.77 ? 221 GLU P O 1 +ATOM 30154 C CB . GLU P 1 221 ? 0.295 35.452 31.691 1.00 171.47 ? 221 GLU P CB 1 +ATOM 30155 C CG . GLU P 1 221 ? 0.422 35.230 33.189 1.00 169.31 ? 221 GLU P CG 1 +ATOM 30156 C CD . GLU P 1 221 ? -0.086 36.406 34.008 1.00 151.58 ? 221 GLU P CD 1 +ATOM 30157 O OE1 . GLU P 1 221 ? 0.162 37.584 33.626 1.00 119.97 ? 221 GLU P OE1 1 +ATOM 30158 O OE2 . GLU P 1 221 ? -0.582 36.137 35.122 1.00 135.10 ? 221 GLU P OE2 1 +ATOM 30159 N N . THR P 1 222 ? 0.915 35.620 28.726 1.00 104.84 ? 222 THR P N 1 +ATOM 30160 C CA . THR P 1 222 ? 0.598 35.801 27.315 1.00 97.09 ? 222 THR P CA 1 +ATOM 30161 C C . THR P 1 222 ? 1.115 34.631 26.483 1.00 101.85 ? 222 THR P C 1 +ATOM 30162 O O . THR P 1 222 ? 0.386 34.090 25.640 1.00 82.55 ? 222 THR P O 1 +ATOM 30163 C CB . THR P 1 222 ? 1.233 37.105 26.789 1.00 91.06 ? 222 THR P CB 1 +ATOM 30164 O OG1 . THR P 1 222 ? 0.547 38.240 27.351 1.00 112.22 ? 222 THR P OG1 1 +ATOM 30165 C CG2 . THR P 1 222 ? 1.219 37.161 25.249 1.00 91.40 ? 222 THR P CG2 1 +ATOM 30166 N N . GLY P 1 223 ? 2.389 34.285 26.689 1.00 92.83 ? 223 GLY P N 1 +ATOM 30167 C CA . GLY P 1 223 ? 3.006 33.151 26.002 1.00 91.91 ? 223 GLY P CA 1 +ATOM 30168 C C . GLY P 1 223 ? 2.236 31.861 26.231 1.00 95.53 ? 223 GLY P C 1 +ATOM 30169 O O . GLY P 1 223 ? 2.074 31.048 25.313 1.00 111.00 ? 223 GLY P O 1 +ATOM 30170 N N . VAL P 1 224 ? 1.758 31.658 27.457 1.00 92.53 ? 224 VAL P N 1 +ATOM 30171 C CA . VAL P 1 224 ? 1.034 30.435 27.784 1.00 105.61 ? 224 VAL P CA 1 +ATOM 30172 C C . VAL P 1 224 ? -0.256 30.388 26.978 1.00 110.53 ? 224 VAL P C 1 +ATOM 30173 O O . VAL P 1 224 ? -0.639 29.336 26.467 1.00 112.67 ? 224 VAL P O 1 +ATOM 30174 C CB . VAL P 1 224 ? 0.718 30.334 29.293 1.00 128.91 ? 224 VAL P CB 1 +ATOM 30175 C CG1 . VAL P 1 224 ? -0.210 29.152 29.563 1.00 124.27 ? 224 VAL P CG1 1 +ATOM 30176 C CG2 . VAL P 1 224 ? 2.008 30.208 30.108 1.00 124.02 ? 224 VAL P CG2 1 +ATOM 30177 N N . ILE P 1 225 ? -0.935 31.530 26.878 1.00 116.78 ? 225 ILE P N 1 +ATOM 30178 C CA . ILE P 1 225 ? -2.175 31.597 26.108 1.00 128.19 ? 225 ILE P CA 1 +ATOM 30179 C C . ILE P 1 225 ? -1.912 31.246 24.641 1.00 135.49 ? 225 ILE P C 1 +ATOM 30180 O O . ILE P 1 225 ? -2.575 30.356 24.112 1.00 125.10 ? 225 ILE P O 1 +ATOM 30181 C CB . ILE P 1 225 ? -2.845 32.974 26.198 1.00 128.17 ? 225 ILE P CB 1 +ATOM 30182 C CG1 . ILE P 1 225 ? -3.372 33.220 27.614 1.00 129.26 ? 225 ILE P CG1 1 +ATOM 30183 C CG2 . ILE P 1 225 ? -4.004 33.061 25.216 1.00 127.10 ? 225 ILE P CG2 1 +ATOM 30184 C CD1 . ILE P 1 225 ? -3.659 34.680 27.913 1.00 147.02 ? 225 ILE P CD1 1 +ATOM 30185 N N . PHE P 1 226 ? -0.925 31.904 24.018 1.00 128.17 ? 226 PHE P N 1 +ATOM 30186 C CA . PHE P 1 226 ? -0.543 31.614 22.623 1.00 116.99 ? 226 PHE P CA 1 +ATOM 30187 C C . PHE P 1 226 ? -0.177 30.146 22.424 1.00 120.53 ? 226 PHE P C 1 +ATOM 30188 O O . PHE P 1 226 ? -0.465 29.566 21.379 1.00 125.71 ? 226 PHE P O 1 +ATOM 30189 C CB . PHE P 1 226 ? 0.636 32.474 22.161 1.00 120.37 ? 226 PHE P CB 1 +ATOM 30190 C CG . PHE P 1 226 ? 0.255 33.893 21.766 1.00 146.16 ? 226 PHE P CG 1 +ATOM 30191 C CD1 . PHE P 1 226 ? -0.640 34.131 20.729 1.00 149.60 ? 226 PHE P CD1 1 +ATOM 30192 C CD2 . PHE P 1 226 ? 0.864 34.997 22.383 1.00 138.79 ? 226 PHE P CD2 1 +ATOM 30193 C CE1 . PHE P 1 226 ? -0.953 35.430 20.347 1.00 145.49 ? 226 PHE P CE1 1 +ATOM 30194 C CE2 . PHE P 1 226 ? 0.595 36.299 21.976 1.00 96.51 ? 226 PHE P CE2 1 +ATOM 30195 C CZ . PHE P 1 226 ? -0.352 36.515 20.991 1.00 145.19 ? 226 PHE P CZ 1 +ATOM 30196 N N . LEU P 1 227 ? 0.388 29.518 23.454 1.00 124.02 ? 227 LEU P N 1 +ATOM 30197 C CA . LEU P 1 227 ? 0.677 28.069 23.403 1.00 118.78 ? 227 LEU P CA 1 +ATOM 30198 C C . LEU P 1 227 ? -0.590 27.260 23.349 1.00 97.96 ? 227 LEU P C 1 +ATOM 30199 O O . LEU P 1 227 ? -0.660 26.293 22.598 1.00 95.62 ? 227 LEU P O 1 +ATOM 30200 C CB . LEU P 1 227 ? 1.459 27.568 24.630 1.00 121.31 ? 227 LEU P CB 1 +ATOM 30201 C CG . LEU P 1 227 ? 2.880 27.028 24.424 1.00 105.61 ? 227 LEU P CG 1 +ATOM 30202 C CD1 . LEU P 1 227 ? 3.476 27.729 23.243 1.00 84.87 ? 227 LEU P CD1 1 +ATOM 30203 C CD2 . LEU P 1 227 ? 3.862 27.075 25.600 1.00 86.81 ? 227 LEU P CD2 1 +ATOM 30204 N N . ILE P 1 228 ? -1.540 27.591 24.224 1.00 79.96 ? 228 ILE P N 1 +ATOM 30205 C CA . ILE P 1 228 ? -2.767 26.808 24.337 1.00 86.18 ? 228 ILE P CA 1 +ATOM 30206 C C . ILE P 1 228 ? -3.539 26.945 23.034 1.00 90.46 ? 228 ILE P C 1 +ATOM 30207 O O . ILE P 1 228 ? -3.992 25.949 22.467 1.00 72.56 ? 228 ILE P O 1 +ATOM 30208 C CB . ILE P 1 228 ? -3.664 27.258 25.507 1.00 86.27 ? 228 ILE P CB 1 +ATOM 30209 C CG1 . ILE P 1 228 ? -2.980 27.006 26.850 1.00 107.69 ? 228 ILE P CG1 1 +ATOM 30210 C CG2 . ILE P 1 228 ? -4.969 26.494 25.487 1.00 71.10 ? 228 ILE P CG2 1 +ATOM 30211 C CD1 . ILE P 1 228 ? -3.606 27.745 28.018 1.00 114.42 ? 228 ILE P CD1 1 +ATOM 30212 N N . ASN P 1 229 ? -3.665 28.179 22.554 1.00 103.81 ? 229 ASN P N 1 +ATOM 30213 C CA . ASN P 1 229 ? -4.391 28.457 21.313 1.00 109.83 ? 229 ASN P CA 1 +ATOM 30214 C C . ASN P 1 229 ? -3.750 27.763 20.113 1.00 104.03 ? 229 ASN P C 1 +ATOM 30215 O O . ASN P 1 229 ? -4.442 27.095 19.341 1.00 130.85 ? 229 ASN P O 1 +ATOM 30216 C CB . ASN P 1 229 ? -4.433 29.958 21.060 1.00 131.82 ? 229 ASN P CB 1 +ATOM 30217 C CG . ASN P 1 229 ? -5.474 30.346 20.036 1.00 157.42 ? 229 ASN P CG 1 +ATOM 30218 O OD1 . ASN P 1 229 ? -6.467 29.641 19.835 1.00 167.80 ? 229 ASN P OD1 1 +ATOM 30219 N ND2 . ASN P 1 229 ? -5.279 31.503 19.417 1.00 193.07 ? 229 ASN P ND2 1 +ATOM 30220 N N . ASP P 1 230 ? -2.423 27.842 20.029 1.00 90.34 ? 230 ASP P N 1 +ATOM 30221 C CA . ASP P 1 230 ? -1.665 27.118 19.025 1.00 80.87 ? 230 ASP P CA 1 +ATOM 30222 C C . ASP P 1 230 ? -1.907 25.595 19.111 1.00 102.86 ? 230 ASP P C 1 +ATOM 30223 O O . ASP P 1 230 ? -2.072 24.923 18.088 1.00 106.99 ? 230 ASP P O 1 +ATOM 30224 C CB . ASP P 1 230 ? -0.171 27.401 19.176 1.00 79.80 ? 230 ASP P CB 1 +ATOM 30225 C CG . ASP P 1 230 ? 0.657 26.816 18.036 1.00 86.66 ? 230 ASP P CG 1 +ATOM 30226 O OD1 . ASP P 1 230 ? 0.580 27.368 16.945 1.00 90.00 ? 230 ASP P OD1 1 +ATOM 30227 O OD2 . ASP P 1 230 ? 1.394 25.829 18.248 1.00 111.28 ? 230 ASP P OD2 1 +ATOM 30228 N N . GLY P 1 231 ? -1.935 25.049 20.327 1.00 109.83 ? 231 GLY P N 1 +ATOM 30229 C CA . GLY P 1 231 ? -2.152 23.615 20.520 1.00 106.01 ? 231 GLY P CA 1 +ATOM 30230 C C . GLY P 1 231 ? -3.562 23.187 20.147 1.00 121.81 ? 231 GLY P C 1 +ATOM 30231 O O . GLY P 1 231 ? -3.772 22.085 19.613 1.00 169.86 ? 231 GLY P O 1 +ATOM 30232 N N . ILE P 1 232 ? -4.530 24.071 20.395 1.00 129.22 ? 232 ILE P N 1 +ATOM 30233 C CA . ILE P 1 232 ? -5.921 23.846 19.962 1.00 134.62 ? 232 ILE P CA 1 +ATOM 30234 C C . ILE P 1 232 ? -6.014 23.729 18.440 1.00 124.64 ? 232 ILE P C 1 +ATOM 30235 O O . ILE P 1 232 ? -6.557 22.756 17.929 1.00 123.83 ? 232 ILE P O 1 +ATOM 30236 C CB . ILE P 1 232 ? -6.862 24.976 20.444 1.00 142.99 ? 232 ILE P CB 1 +ATOM 30237 C CG1 . ILE P 1 232 ? -7.080 24.854 21.955 1.00 157.46 ? 232 ILE P CG1 1 +ATOM 30238 C CG2 . ILE P 1 232 ? -8.199 24.942 19.705 1.00 134.62 ? 232 ILE P CG2 1 +ATOM 30239 C CD1 . ILE P 1 232 ? -7.617 26.113 22.600 1.00 178.05 ? 232 ILE P CD1 1 +ATOM 30240 N N . ASP P 1 233 ? -5.443 24.704 17.736 1.00 116.74 ? 233 ASP P N 1 +ATOM 30241 C CA . ASP P 1 233 ? -5.364 24.675 16.276 1.00 112.09 ? 233 ASP P CA 1 +ATOM 30242 C C . ASP P 1 233 ? -4.710 23.386 15.771 1.00 126.13 ? 233 ASP P C 1 +ATOM 30243 O O . ASP P 1 233 ? -5.234 22.734 14.876 1.00 147.15 ? 233 ASP P O 1 +ATOM 30244 C CB . ASP P 1 233 ? -4.581 25.889 15.745 1.00 116.67 ? 233 ASP P CB 1 +ATOM 30245 C CG . ASP P 1 233 ? -5.278 27.221 16.030 1.00 109.37 ? 233 ASP P CG 1 +ATOM 30246 O OD1 . ASP P 1 233 ? -6.250 27.241 16.816 1.00 121.11 ? 233 ASP P OD1 1 +ATOM 30247 O OD2 . ASP P 1 233 ? -4.803 28.260 15.517 1.00 97.97 ? 233 ASP P OD2 1 +ATOM 30248 N N . ARG P 1 234 ? -3.553 23.033 16.329 1.00 162.96 ? 234 ARG P N 1 +ATOM 30249 C CA . ARG P 1 234 ? -2.748 21.916 15.812 1.00 187.40 ? 234 ARG P CA 1 +ATOM 30250 C C . ARG P 1 234 ? -3.209 20.542 16.295 1.00 158.38 ? 234 ARG P C 1 +ATOM 30251 O O . ARG P 1 234 ? -2.639 19.521 15.902 1.00 136.46 ? 234 ARG P O 1 +ATOM 30252 C CB . ARG P 1 234 ? -1.273 22.123 16.163 1.00 215.18 ? 234 ARG P CB 1 +ATOM 30253 C CG . ARG P 1 234 ? -0.636 23.223 15.333 1.00 218.61 ? 234 ARG P CG 1 +ATOM 30254 C CD . ARG P 1 234 ? 0.610 23.811 15.984 1.00 193.24 ? 234 ARG P CD 1 +ATOM 30255 N NE . ARG P 1 234 ? 1.101 24.937 15.192 1.00 152.30 ? 234 ARG P NE 1 +ATOM 30256 C CZ . ARG P 1 234 ? 2.307 25.004 14.649 1.00 141.00 ? 234 ARG P CZ 1 +ATOM 30257 N NH1 . ARG P 1 234 ? 3.200 24.048 14.914 1.00 158.65 ? 234 ARG P NH1 1 +ATOM 30258 N NH2 . ARG P 1 234 ? 2.614 25.992 13.808 1.00 98.24 ? 234 ARG P NH2 1 +ATOM 30259 N N . GLY P 1 235 ? -4.255 20.513 17.118 1.00 140.91 ? 235 GLY P N 1 +ATOM 30260 C CA . GLY P 1 235 ? -4.846 19.256 17.564 1.00 125.87 ? 235 GLY P CA 1 +ATOM 30261 C C . GLY P 1 235 ? -4.019 18.549 18.623 1.00 105.49 ? 235 GLY P C 1 +ATOM 30262 O O . GLY P 1 235 ? -3.995 17.319 18.674 1.00 101.56 ? 235 GLY P O 1 +ATOM 30263 N N . LEU P 1 236 ? -3.327 19.313 19.461 1.00 108.61 ? 236 LEU P N 1 +ATOM 30264 C CA . LEU P 1 236 ? -2.701 18.730 20.654 1.00 125.01 ? 236 LEU P CA 1 +ATOM 30265 C C . LEU P 1 236 ? -3.790 18.407 21.672 1.00 124.81 ? 236 LEU P C 1 +ATOM 30266 O O . LEU P 1 236 ? -3.825 17.315 22.233 1.00 129.07 ? 236 LEU P O 1 +ATOM 30267 C CB . LEU P 1 236 ? -1.663 19.680 21.281 1.00 147.64 ? 236 LEU P CB 1 +ATOM 30268 C CG . LEU P 1 236 ? -0.245 19.691 20.690 1.00 164.40 ? 236 LEU P CG 1 +ATOM 30269 C CD1 . LEU P 1 236 ? -0.198 20.503 19.400 1.00 154.47 ? 236 LEU P CD1 1 +ATOM 30270 C CD2 . LEU P 1 236 ? 0.750 20.255 21.696 1.00 173.00 ? 236 LEU P CD2 1 +ATOM 30271 N N . TRP P 1 237 ? -4.670 19.373 21.913 1.00 138.24 ? 237 TRP P N 1 +ATOM 30272 C CA . TRP P 1 237 ? -5.736 19.223 22.905 1.00 146.35 ? 237 TRP P CA 1 +ATOM 30273 C C . TRP P 1 237 ? -7.042 19.836 22.384 1.00 151.42 ? 237 TRP P C 1 +ATOM 30274 O O . TRP P 1 237 ? -7.027 20.587 21.400 1.00 110.92 ? 237 TRP P O 1 +ATOM 30275 C CB . TRP P 1 237 ? -5.316 19.862 24.233 1.00 137.02 ? 237 TRP P CB 1 +ATOM 30276 C CG . TRP P 1 237 ? -4.437 21.060 24.050 1.00 134.85 ? 237 TRP P CG 1 +ATOM 30277 C CD1 . TRP P 1 237 ? -4.796 22.251 23.500 1.00 148.74 ? 237 TRP P CD1 1 +ATOM 30278 C CD2 . TRP P 1 237 ? -3.054 21.184 24.409 1.00 128.75 ? 237 TRP P CD2 1 +ATOM 30279 N NE1 . TRP P 1 237 ? -3.727 23.114 23.498 1.00 145.85 ? 237 TRP P NE1 1 +ATOM 30280 C CE2 . TRP P 1 237 ? -2.645 22.488 24.054 1.00 129.20 ? 237 TRP P CE2 1 +ATOM 30281 C CE3 . TRP P 1 237 ? -2.136 20.338 25.025 1.00 133.29 ? 237 TRP P CE3 1 +ATOM 30282 C CZ2 . TRP P 1 237 ? -1.347 22.952 24.254 1.00 116.47 ? 237 TRP P CZ2 1 +ATOM 30283 C CZ3 . TRP P 1 237 ? -0.848 20.807 25.238 1.00 151.07 ? 237 TRP P CZ3 1 +ATOM 30284 C CH2 . TRP P 1 237 ? -0.470 22.112 24.857 1.00 132.40 ? 237 TRP P CH2 1 +ATOM 30285 N N . ASP P 1 238 ? -8.155 19.499 23.039 1.00 151.92 ? 238 ASP P N 1 +ATOM 30286 C CA . ASP P 1 238 ? -9.485 19.878 22.559 1.00 162.67 ? 238 ASP P CA 1 +ATOM 30287 C C . ASP P 1 238 ? -10.355 20.552 23.628 1.00 167.81 ? 238 ASP P C 1 +ATOM 30288 O O . ASP P 1 238 ? -10.263 20.236 24.818 1.00 125.61 ? 238 ASP P O 1 +ATOM 30289 C CB . ASP P 1 238 ? -10.232 18.661 22.011 1.00 150.95 ? 238 ASP P CB 1 +ATOM 30290 C CG . ASP P 1 238 ? -9.469 17.952 20.917 1.00 149.20 ? 238 ASP P CG 1 +ATOM 30291 O OD1 . ASP P 1 238 ? -8.549 17.186 21.253 1.00 169.19 ? 238 ASP P OD1 1 +ATOM 30292 O OD2 . ASP P 1 238 ? -9.775 18.161 19.723 1.00 165.48 ? 238 ASP P OD2 1 +ATOM 30293 N N . LEU P 1 239 ? -11.225 21.460 23.175 1.00 154.09 ? 239 LEU P N 1 +ATOM 30294 C CA . LEU P 1 239 ? -12.106 22.215 24.060 1.00 117.84 ? 239 LEU P CA 1 +ATOM 30295 C C . LEU P 1 239 ? -13.264 21.348 24.500 1.00 118.35 ? 239 LEU P C 1 +ATOM 30296 O O . LEU P 1 239 ? -13.757 20.514 23.737 1.00 120.31 ? 239 LEU P O 1 +ATOM 30297 C CB . LEU P 1 239 ? -12.644 23.467 23.358 1.00 104.08 ? 239 LEU P CB 1 +ATOM 30298 C CG . LEU P 1 239 ? -11.742 24.691 23.197 1.00 127.95 ? 239 LEU P CG 1 +ATOM 30299 C CD1 . LEU P 1 239 ? -12.508 25.851 22.580 1.00 140.97 ? 239 LEU P CD1 1 +ATOM 30300 C CD2 . LEU P 1 239 ? -11.162 25.111 24.533 1.00 147.82 ? 239 LEU P CD2 1 +ATOM 30301 N N . GLN P 1 240 ? -13.693 21.550 25.740 1.00 130.61 ? 240 GLN P N 1 +ATOM 30302 C CA . GLN P 1 240 ? -14.931 20.946 26.234 1.00 135.09 ? 240 GLN P CA 1 +ATOM 30303 C C . GLN P 1 240 ? -16.103 21.295 25.316 1.00 145.76 ? 240 GLN P C 1 +ATOM 30304 O O . GLN P 1 240 ? -16.772 20.408 24.777 1.00 180.04 ? 240 GLN P O 1 +ATOM 30305 C CB . GLN P 1 240 ? -15.226 21.427 27.661 1.00 133.38 ? 240 GLN P CB 1 +ATOM 30306 C CG . GLN P 1 240 ? -16.386 20.701 28.333 1.00 128.40 ? 240 GLN P CG 1 +ATOM 30307 C CD . GLN P 1 240 ? -16.089 19.231 28.565 1.00 126.13 ? 240 GLN P CD 1 +ATOM 30308 O OE1 . GLN P 1 240 ? -15.394 18.872 29.519 1.00 153.18 ? 240 GLN P OE1 1 +ATOM 30309 N NE2 . GLN P 1 240 ? -16.572 18.376 27.666 1.00 127.61 ? 240 GLN P NE2 1 +ATOM 30310 N N . ASN P 1 241 ? -16.312 22.592 25.120 1.00 145.87 ? 241 ASN P N 1 +ATOM 30311 C CA . ASN P 1 241 ? -17.367 23.101 24.251 1.00 161.19 ? 241 ASN P CA 1 +ATOM 30312 C C . ASN P 1 241 ? -16.800 23.613 22.939 1.00 172.51 ? 241 ASN P C 1 +ATOM 30313 O O . ASN P 1 241 ? -16.116 24.651 22.908 1.00 213.54 ? 241 ASN P O 1 +ATOM 30314 C CB . ASN P 1 241 ? -18.096 24.246 24.944 1.00 173.55 ? 241 ASN P CB 1 +ATOM 30315 C CG . ASN P 1 241 ? -19.406 23.815 25.546 1.00 183.81 ? 241 ASN P CG 1 +ATOM 30316 O OD1 . ASN P 1 241 ? -20.460 24.070 24.972 1.00 199.16 ? 241 ASN P OD1 1 +ATOM 30317 N ND2 . ASN P 1 241 ? -19.353 23.141 26.695 1.00 179.67 ? 241 ASN P ND2 1 +ATOM 30318 N N . LYS P 1 242 ? -17.092 22.897 21.857 1.00 152.67 ? 242 LYS P N 1 +ATOM 30319 C CA . LYS P 1 242 ? -16.581 23.271 20.541 1.00 147.28 ? 242 LYS P CA 1 +ATOM 30320 C C . LYS P 1 242 ? -17.202 24.595 20.128 1.00 161.40 ? 242 LYS P C 1 +ATOM 30321 O O . LYS P 1 242 ? -16.610 25.365 19.354 1.00 129.81 ? 242 LYS P O 1 +ATOM 30322 C CB . LYS P 1 242 ? -16.879 22.175 19.519 1.00 152.71 ? 242 LYS P CB 1 +ATOM 30323 C CG . LYS P 1 242 ? -16.467 20.777 19.977 1.00 154.25 ? 242 LYS P CG 1 +ATOM 30324 C CD . LYS P 1 242 ? -15.556 20.089 18.973 1.00 167.96 ? 242 LYS P CD 1 +ATOM 30325 C CE . LYS P 1 242 ? -14.356 19.454 19.661 1.00 166.05 ? 242 LYS P CE 1 +ATOM 30326 N NZ . LYS P 1 242 ? -13.524 18.642 18.731 1.00 165.70 ? 242 LYS P NZ 1 +ATOM 30327 N N . ALA P 1 243 ? -18.380 24.864 20.702 1.00 185.31 ? 243 ALA P N 1 +ATOM 30328 C CA . ALA P 1 243 ? -19.088 26.135 20.542 1.00 208.14 ? 243 ALA P CA 1 +ATOM 30329 C C . ALA P 1 243 ? -18.286 27.304 21.108 1.00 219.74 ? 243 ALA P C 1 +ATOM 30330 O O . ALA P 1 243 ? -18.549 28.461 20.758 1.00 277.24 ? 243 ALA P O 1 +ATOM 30331 C CB . ALA P 1 243 ? -20.453 26.068 21.221 1.00 180.38 ? 243 ALA P CB 1 +ATOM 30332 N N . GLU P 1 244 ? -17.321 27.012 21.983 1.00 180.09 ? 244 GLU P N 1 +ATOM 30333 C CA . GLU P 1 244 ? -16.538 28.072 22.611 1.00 151.26 ? 244 GLU P CA 1 +ATOM 30334 C C . GLU P 1 244 ? -15.260 28.372 21.849 1.00 132.17 ? 244 GLU P C 1 +ATOM 30335 O O . GLU P 1 244 ? -14.408 29.094 22.348 1.00 122.79 ? 244 GLU P O 1 +ATOM 30336 C CB . GLU P 1 244 ? -16.207 27.719 24.059 1.00 152.66 ? 244 GLU P CB 1 +ATOM 30337 C CG . GLU P 1 244 ? -17.396 27.814 25.002 1.00 161.66 ? 244 GLU P CG 1 +ATOM 30338 C CD . GLU P 1 244 ? -16.995 27.714 26.461 1.00 168.43 ? 244 GLU P CD 1 +ATOM 30339 O OE1 . GLU P 1 244 ? -16.705 26.591 26.931 1.00 168.94 ? 244 GLU P OE1 1 +ATOM 30340 O OE2 . GLU P 1 244 ? -16.961 28.760 27.141 1.00 174.52 ? 244 GLU P OE2 1 +ATOM 30341 N N . ARG P 1 245 ? -15.126 27.837 20.640 1.00 122.08 ? 245 ARG P N 1 +ATOM 30342 C CA . ARG P 1 245 ? -14.002 28.200 19.785 1.00 144.81 ? 245 ARG P CA 1 +ATOM 30343 C C . ARG P 1 245 ? -13.880 29.706 19.514 1.00 137.41 ? 245 ARG P C 1 +ATOM 30344 O O . ARG P 1 245 ? -12.768 30.227 19.412 1.00 123.86 ? 245 ARG P O 1 +ATOM 30345 C CB . ARG P 1 245 ? -14.068 27.487 18.452 1.00 159.66 ? 245 ARG P CB 1 +ATOM 30346 C CG . ARG P 1 245 ? -12.790 27.699 17.651 1.00 156.21 ? 245 ARG P CG 1 +ATOM 30347 C CD . ARG P 1 245 ? -12.726 26.918 16.421 1.00 153.91 ? 245 ARG P CD 1 +ATOM 30348 N NE . ARG P 1 245 ? -11.733 27.501 15.535 1.00 149.12 ? 245 ARG P NE 1 +ATOM 30349 C CZ . ARG P 1 245 ? -10.415 27.350 15.636 1.00 136.61 ? 245 ARG P CZ 1 +ATOM 30350 N NH1 . ARG P 1 245 ? -9.871 26.622 16.591 1.00 121.11 ? 245 ARG P NH1 1 +ATOM 30351 N NH2 . ARG P 1 245 ? -9.620 27.950 14.750 1.00 155.64 ? 245 ARG P NH2 1 +ATOM 30352 N N . GLN P 1 246 ? -15.015 30.386 19.362 1.00 153.18 ? 246 GLN P N 1 +ATOM 30353 C CA . GLN P 1 246 ? -15.007 31.813 19.036 1.00 154.16 ? 246 GLN P CA 1 +ATOM 30354 C C . GLN P 1 246 ? -15.059 32.672 20.298 1.00 163.56 ? 246 GLN P C 1 +ATOM 30355 O O . GLN P 1 246 ? -15.455 33.833 20.250 1.00 204.57 ? 246 GLN P O 1 +ATOM 30356 C CB . GLN P 1 246 ? -16.169 32.174 18.102 1.00 147.98 ? 246 GLN P CB 1 +ATOM 30357 C CG . GLN P 1 246 ? -16.021 31.653 16.689 1.00 139.90 ? 246 GLN P CG 1 +ATOM 30358 C CD . GLN P 1 246 ? -16.306 30.170 16.597 1.00 164.25 ? 246 GLN P CD 1 +ATOM 30359 O OE1 . GLN P 1 246 ? -17.291 29.677 17.152 1.00 140.96 ? 246 GLN P OE1 1 +ATOM 30360 N NE2 . GLN P 1 246 ? -15.465 29.453 15.858 1.00 208.75 ? 246 GLN P NE2 1 +ATOM 30361 N N . ASN P 1 247 ? -14.659 32.090 21.424 1.00 153.44 ? 247 ASN P N 1 +ATOM 30362 C CA . ASN P 1 247 ? -14.409 32.838 22.658 1.00 143.66 ? 247 ASN P CA 1 +ATOM 30363 C C . ASN P 1 247 ? -13.667 34.149 22.404 1.00 148.98 ? 247 ASN P C 1 +ATOM 30364 O O . ASN P 1 247 ? -12.732 34.187 21.595 1.00 168.36 ? 247 ASN P O 1 +ATOM 30365 C CB . ASN P 1 247 ? -13.568 31.984 23.600 1.00 150.36 ? 247 ASN P CB 1 +ATOM 30366 C CG . ASN P 1 247 ? -13.766 32.359 25.044 1.00 143.46 ? 247 ASN P CG 1 +ATOM 30367 O OD1 . ASN P 1 247 ? -12.865 32.903 25.688 1.00 116.73 ? 247 ASN P OD1 1 +ATOM 30368 N ND2 . ASN P 1 247 ? -14.929 32.009 25.581 1.00 149.66 ? 247 ASN P ND2 1 +ATOM 30369 N N . ASP P 1 248 ? -14.083 35.214 23.088 1.00 164.76 ? 248 ASP P N 1 +ATOM 30370 C CA . ASP P 1 248 ? -13.506 36.558 22.877 1.00 195.01 ? 248 ASP P CA 1 +ATOM 30371 C C . ASP P 1 248 ? -11.981 36.536 22.997 1.00 190.89 ? 248 ASP P C 1 +ATOM 30372 O O . ASP P 1 248 ? -11.258 37.120 22.179 1.00 164.46 ? 248 ASP P O 1 +ATOM 30373 C CB . ASP P 1 248 ? -14.064 37.556 23.907 1.00 203.17 ? 248 ASP P CB 1 +ATOM 30374 C CG . ASP P 1 248 ? -15.516 37.922 23.656 1.00 208.17 ? 248 ASP P CG 1 +ATOM 30375 O OD1 . ASP P 1 248 ? -15.913 38.068 22.482 1.00 219.29 ? 248 ASP P OD1 1 +ATOM 30376 O OD2 . ASP P 1 248 ? -16.259 38.083 24.644 1.00 206.71 ? 248 ASP P OD2 1 +ATOM 30377 N N . ILE P 1 249 ? -11.506 35.874 24.047 1.00 184.27 ? 249 ILE P N 1 +ATOM 30378 C CA . ILE P 1 249 ? -10.087 35.831 24.359 1.00 158.93 ? 249 ILE P CA 1 +ATOM 30379 C C . ILE P 1 249 ? -9.341 35.048 23.277 1.00 162.57 ? 249 ILE P C 1 +ATOM 30380 O O . ILE P 1 249 ? -8.346 35.517 22.718 1.00 164.04 ? 249 ILE P O 1 +ATOM 30381 C CB . ILE P 1 249 ? -9.861 35.186 25.740 1.00 145.12 ? 249 ILE P CB 1 +ATOM 30382 C CG1 . ILE P 1 249 ? -10.513 36.035 26.842 1.00 144.33 ? 249 ILE P CG1 1 +ATOM 30383 C CG2 . ILE P 1 249 ? -8.376 35.049 26.019 1.00 162.14 ? 249 ILE P CG2 1 +ATOM 30384 C CD1 . ILE P 1 249 ? -10.774 35.289 28.136 1.00 138.34 ? 249 ILE P CD1 1 +ATOM 30385 N N . LEU P 1 250 ? -9.860 33.867 22.953 1.00 162.93 ? 250 LEU P N 1 +ATOM 30386 C CA . LEU P 1 250 ? -9.226 32.987 21.962 1.00 147.50 ? 250 LEU P CA 1 +ATOM 30387 C C . LEU P 1 250 ? -9.116 33.629 20.584 1.00 143.70 ? 250 LEU P C 1 +ATOM 30388 O O . LEU P 1 250 ? -8.116 33.442 19.894 1.00 120.21 ? 250 LEU P O 1 +ATOM 30389 C CB . LEU P 1 250 ? -9.988 31.663 21.855 1.00 142.34 ? 250 LEU P CB 1 +ATOM 30390 C CG . LEU P 1 250 ? -9.687 30.641 22.960 1.00 132.40 ? 250 LEU P CG 1 +ATOM 30391 C CD1 . LEU P 1 250 ? -10.682 29.489 22.958 1.00 112.55 ? 250 LEU P CD1 1 +ATOM 30392 C CD2 . LEU P 1 250 ? -8.273 30.115 22.807 1.00 135.28 ? 250 LEU P CD2 1 +ATOM 30393 N N . VAL P 1 251 ? -10.144 34.382 20.191 1.00 161.08 ? 251 VAL P N 1 +ATOM 30394 C CA . VAL P 1 251 ? -10.126 35.074 18.901 1.00 179.36 ? 251 VAL P CA 1 +ATOM 30395 C C . VAL P 1 251 ? -9.242 36.321 18.941 1.00 174.81 ? 251 VAL P C 1 +ATOM 30396 O O . VAL P 1 251 ? -8.733 36.766 17.909 1.00 195.16 ? 251 VAL P O 1 +ATOM 30397 C CB . VAL P 1 251 ? -11.544 35.459 18.415 1.00 177.02 ? 251 VAL P CB 1 +ATOM 30398 C CG1 . VAL P 1 251 ? -12.442 34.226 18.367 1.00 169.49 ? 251 VAL P CG1 1 +ATOM 30399 C CG2 . VAL P 1 251 ? -12.150 36.561 19.278 1.00 165.71 ? 251 VAL P CG2 1 +ATOM 30400 N N . LYS P 1 252 ? -9.074 36.888 20.130 1.00 152.76 ? 252 LYS P N 1 +ATOM 30401 C CA . LYS P 1 252 ? -8.179 38.022 20.309 1.00 158.00 ? 252 LYS P CA 1 +ATOM 30402 C C . LYS P 1 252 ? -6.721 37.597 20.062 1.00 172.93 ? 252 LYS P C 1 +ATOM 30403 O O . LYS P 1 252 ? -5.974 38.267 19.330 1.00 154.05 ? 252 LYS P O 1 +ATOM 30404 C CB . LYS P 1 252 ? -8.372 38.595 21.716 1.00 148.38 ? 252 LYS P CB 1 +ATOM 30405 C CG . LYS P 1 252 ? -7.484 39.777 22.068 1.00 151.61 ? 252 LYS P CG 1 +ATOM 30406 C CD . LYS P 1 252 ? -7.759 40.230 23.496 1.00 174.98 ? 252 LYS P CD 1 +ATOM 30407 C CE . LYS P 1 252 ? -6.472 40.433 24.282 1.00 206.39 ? 252 LYS P CE 1 +ATOM 30408 N NZ . LYS P 1 252 ? -6.712 40.615 25.742 1.00 199.23 ? 252 LYS P NZ 1 +ATOM 30409 N N . TYR P 1 253 ? -6.329 36.469 20.654 1.00 180.35 ? 253 TYR P N 1 +ATOM 30410 C CA . TYR P 1 253 ? -4.956 35.960 20.521 1.00 165.60 ? 253 TYR P CA 1 +ATOM 30411 C C . TYR P 1 253 ? -4.747 35.303 19.169 1.00 172.17 ? 253 TYR P C 1 +ATOM 30412 O O . TYR P 1 253 ? -3.641 35.338 18.612 1.00 157.76 ? 253 TYR P O 1 +ATOM 30413 C CB . TYR P 1 253 ? -4.618 34.990 21.659 1.00 140.02 ? 253 TYR P CB 1 +ATOM 30414 C CG . TYR P 1 253 ? -4.441 35.726 22.979 1.00 161.36 ? 253 TYR P CG 1 +ATOM 30415 C CD1 . TYR P 1 253 ? -3.228 36.333 23.306 1.00 157.59 ? 253 TYR P CD1 1 +ATOM 30416 C CD2 . TYR P 1 253 ? -5.510 35.893 23.858 1.00 173.52 ? 253 TYR P CD2 1 +ATOM 30417 C CE1 . TYR P 1 253 ? -3.081 37.047 24.485 1.00 135.74 ? 253 TYR P CE1 1 +ATOM 30418 C CE2 . TYR P 1 253 ? -5.362 36.593 25.051 1.00 145.75 ? 253 TYR P CE2 1 +ATOM 30419 C CZ . TYR P 1 253 ? -4.146 37.167 25.357 1.00 126.81 ? 253 TYR P CZ 1 +ATOM 30420 O OH . TYR P 1 253 ? -3.978 37.829 26.546 1.00 99.68 ? 253 TYR P OH 1 +ATOM 30421 N N . ARG P 1 254 ? -5.817 34.715 18.640 1.00 171.00 ? 254 ARG P N 1 +ATOM 30422 C CA . ARG P 1 254 ? -5.820 34.224 17.264 1.00 171.34 ? 254 ARG P CA 1 +ATOM 30423 C C . ARG P 1 254 ? -5.526 35.378 16.304 1.00 160.97 ? 254 ARG P C 1 +ATOM 30424 O O . ARG P 1 254 ? -4.787 35.208 15.326 1.00 153.15 ? 254 ARG P O 1 +ATOM 30425 C CB . ARG P 1 254 ? -7.175 33.587 16.915 1.00 177.42 ? 254 ARG P CB 1 +ATOM 30426 C CG . ARG P 1 254 ? -7.215 32.958 15.531 1.00 165.44 ? 254 ARG P CG 1 +ATOM 30427 C CD . ARG P 1 254 ? -8.374 31.996 15.354 1.00 170.36 ? 254 ARG P CD 1 +ATOM 30428 N NE . ARG P 1 254 ? -8.286 30.810 16.207 1.00 181.04 ? 254 ARG P NE 1 +ATOM 30429 C CZ . ARG P 1 254 ? -9.063 30.555 17.261 1.00 173.72 ? 254 ARG P CZ 1 +ATOM 30430 N NH1 . ARG P 1 254 ? -9.990 31.421 17.648 1.00 161.18 ? 254 ARG P NH1 1 +ATOM 30431 N NH2 . ARG P 1 254 ? -8.937 29.398 17.912 1.00 170.59 ? 254 ARG P NH2 1 +ATOM 30432 N N . HIS P 1 255 ? -6.102 36.545 16.600 1.00 161.35 ? 255 HIS P N 1 +ATOM 30433 C CA . HIS P 1 255 ? -5.925 37.741 15.772 1.00 173.91 ? 255 HIS P CA 1 +ATOM 30434 C C . HIS P 1 255 ? -4.516 38.314 15.846 1.00 160.49 ? 255 HIS P C 1 +ATOM 30435 O O . HIS P 1 255 ? -3.990 38.810 14.851 1.00 167.87 ? 255 HIS P O 1 +ATOM 30436 C CB . HIS P 1 255 ? -6.943 38.825 16.148 1.00 178.66 ? 255 HIS P CB 1 +ATOM 30437 C CG . HIS P 1 255 ? -8.045 38.990 15.147 1.00 178.47 ? 255 HIS P CG 1 +ATOM 30438 N ND1 . HIS P 1 255 ? -9.090 38.098 15.034 1.00 156.62 ? 255 HIS P ND1 1 +ATOM 30439 C CD2 . HIS P 1 255 ? -8.253 39.937 14.201 1.00 168.92 ? 255 HIS P CD2 1 +ATOM 30440 C CE1 . HIS P 1 255 ? -9.896 38.490 14.063 1.00 165.95 ? 255 HIS P CE1 1 +ATOM 30441 N NE2 . HIS P 1 255 ? -9.413 39.605 13.544 1.00 178.87 ? 255 HIS P NE2 1 +ATOM 30442 N N . MET P 1 256 ? -3.885 38.216 17.009 1.00 159.72 ? 256 MET P N 1 +ATOM 30443 C CA . MET P 1 256 ? -2.508 38.695 17.141 1.00 158.31 ? 256 MET P CA 1 +ATOM 30444 C C . MET P 1 256 ? -1.513 37.851 16.308 1.00 170.33 ? 256 MET P C 1 +ATOM 30445 O O . MET P 1 256 ? -0.443 38.349 15.930 1.00 111.01 ? 256 MET P O 1 +ATOM 30446 C CB . MET P 1 256 ? -2.103 38.753 18.621 1.00 169.48 ? 256 MET P CB 1 +ATOM 30447 C CG . MET P 1 256 ? -3.081 39.536 19.493 1.00 167.37 ? 256 MET P CG 1 +ATOM 30448 S SD . MET P 1 256 ? -2.437 40.090 21.086 1.00 170.23 ? 256 MET P SD 1 +ATOM 30449 C CE . MET P 1 256 ? -1.274 41.343 20.534 1.00 142.51 ? 256 MET P CE 1 +ATOM 30450 N N . SER P 1 257 ? -1.883 36.596 16.016 1.00 186.64 ? 257 SER P N 1 +ATOM 30451 C CA . SER P 1 257 ? -1.092 35.707 15.154 1.00 170.20 ? 257 SER P CA 1 +ATOM 30452 C C . SER P 1 257 ? -1.276 36.063 13.686 1.00 149.13 ? 257 SER P C 1 +ATOM 30453 O O . SER P 1 257 ? -0.525 36.889 13.156 1.00 166.11 ? 257 SER P O 1 +ATOM 30454 C CB . SER P 1 257 ? -1.494 34.246 15.370 1.00 155.31 ? 257 SER P CB 1 +ATOM 30455 O OG . SER P 1 257 ? -1.654 33.961 16.752 1.00 125.99 ? 257 SER P OG 1 +ATOM 30456 N N . LEU Q 1 2 ? -1.730 54.819 47.273 1.00 137.10 ? 2 LEU Q N 1 +ATOM 30457 C CA . LEU Q 1 2 ? -0.714 54.807 46.174 1.00 131.46 ? 2 LEU Q CA 1 +ATOM 30458 C C . LEU Q 1 2 ? 0.713 54.748 46.767 1.00 142.54 ? 2 LEU Q C 1 +ATOM 30459 O O . LEU Q 1 2 ? 1.503 55.722 46.704 1.00 94.72 ? 2 LEU Q O 1 +ATOM 30460 C CB . LEU Q 1 2 ? -0.889 56.013 45.245 1.00 129.29 ? 2 LEU Q CB 1 +ATOM 30461 C CG . LEU Q 1 2 ? -2.215 56.165 44.468 1.00 124.98 ? 2 LEU Q CG 1 +ATOM 30462 C CD1 . LEU Q 1 2 ? -2.171 57.449 43.636 1.00 122.40 ? 2 LEU Q CD1 1 +ATOM 30463 C CD2 . LEU Q 1 2 ? -2.574 54.971 43.579 1.00 111.77 ? 2 LEU Q CD2 1 +ATOM 30464 N N . THR Q 1 3 ? 0.966 53.622 47.441 1.00 165.17 ? 3 THR Q N 1 +ATOM 30465 C CA . THR Q 1 3 ? 2.308 53.146 47.800 1.00 175.49 ? 3 THR Q CA 1 +ATOM 30466 C C . THR Q 1 3 ? 2.400 51.608 47.641 1.00 192.22 ? 3 THR Q C 1 +ATOM 30467 O O . THR Q 1 3 ? 3.451 50.997 47.876 1.00 166.34 ? 3 THR Q O 1 +ATOM 30468 C CB . THR Q 1 3 ? 2.683 53.504 49.252 1.00 157.12 ? 3 THR Q CB 1 +ATOM 30469 O OG1 . THR Q 1 3 ? 1.858 52.754 50.168 1.00 138.36 ? 3 THR Q OG1 1 +ATOM 30470 C CG2 . THR Q 1 3 ? 2.555 55.012 49.501 1.00 145.65 ? 3 THR Q CG2 1 +ATOM 30471 N N . ALA Q 1 4 ? 1.275 50.982 47.309 1.00 180.40 ? 4 ALA Q N 1 +ATOM 30472 C CA . ALA Q 1 4 ? 1.289 49.649 46.714 1.00 149.95 ? 4 ALA Q CA 1 +ATOM 30473 C C . ALA Q 1 4 ? 1.771 49.785 45.254 1.00 151.77 ? 4 ALA Q C 1 +ATOM 30474 O O . ALA Q 1 4 ? 2.173 50.868 44.824 1.00 135.92 ? 4 ALA Q O 1 +ATOM 30475 C CB . ALA Q 1 4 ? -0.098 49.019 46.812 1.00 139.95 ? 4 ALA Q CB 1 +ATOM 30476 N N . PRO Q 1 5 ? 1.790 48.688 44.487 1.00 164.04 ? 5 PRO Q N 1 +ATOM 30477 C CA . PRO Q 1 5 ? 2.537 48.881 43.250 1.00 144.60 ? 5 PRO Q CA 1 +ATOM 30478 C C . PRO Q 1 5 ? 1.763 49.658 42.178 1.00 113.93 ? 5 PRO Q C 1 +ATOM 30479 O O . PRO Q 1 5 ? 0.551 49.856 42.294 1.00 131.15 ? 5 PRO Q O 1 +ATOM 30480 C CB . PRO Q 1 5 ? 2.832 47.441 42.807 1.00 165.97 ? 5 PRO Q CB 1 +ATOM 30481 C CG . PRO Q 1 5 ? 1.715 46.613 43.383 1.00 188.95 ? 5 PRO Q CG 1 +ATOM 30482 C CD . PRO Q 1 5 ? 1.103 47.378 44.529 1.00 180.71 ? 5 PRO Q CD 1 +ATOM 30483 N N . PRO Q 1 6 ? 2.451 50.064 41.113 1.00 95.59 ? 6 PRO Q N 1 +ATOM 30484 C CA . PRO Q 1 6 ? 1.787 50.514 39.875 1.00 115.97 ? 6 PRO Q CA 1 +ATOM 30485 C C . PRO Q 1 6 ? 1.232 49.377 39.003 1.00 112.68 ? 6 PRO Q C 1 +ATOM 30486 O O . PRO Q 1 6 ? 1.769 48.277 39.023 1.00 62.58 ? 6 PRO Q O 1 +ATOM 30487 C CB . PRO Q 1 6 ? 2.886 51.291 39.131 1.00 106.65 ? 6 PRO Q CB 1 +ATOM 30488 C CG . PRO Q 1 6 ? 4.168 50.858 39.736 1.00 95.13 ? 6 PRO Q CG 1 +ATOM 30489 C CD . PRO Q 1 6 ? 3.907 50.221 41.074 1.00 90.40 ? 6 PRO Q CD 1 +ATOM 30490 N N . LYS Q 1 7 ? 0.206 49.673 38.197 1.00 129.80 ? 7 LYS Q N 1 +ATOM 30491 C CA . LYS Q 1 7 ? -0.398 48.665 37.320 1.00 140.10 ? 7 LYS Q CA 1 +ATOM 30492 C C . LYS Q 1 7 ? 0.137 48.736 35.890 1.00 136.61 ? 7 LYS Q C 1 +ATOM 30493 O O . LYS Q 1 7 ? 0.846 49.674 35.519 1.00 93.14 ? 7 LYS Q O 1 +ATOM 30494 C CB . LYS Q 1 7 ? -1.922 48.782 37.302 1.00 143.19 ? 7 LYS Q CB 1 +ATOM 30495 C CG . LYS Q 1 7 ? -2.591 48.411 38.606 1.00 166.52 ? 7 LYS Q CG 1 +ATOM 30496 C CD . LYS Q 1 7 ? -3.067 49.624 39.403 1.00 163.00 ? 7 LYS Q CD 1 +ATOM 30497 C CE . LYS Q 1 7 ? -3.998 49.195 40.525 1.00 158.68 ? 7 LYS Q CE 1 +ATOM 30498 N NZ . LYS Q 1 7 ? -3.940 50.127 41.681 1.00 154.72 ? 7 LYS Q NZ 1 +ATOM 30499 N N . GLU Q 1 8 ? -0.169 47.699 35.113 1.00 160.66 ? 8 GLU Q N 1 +ATOM 30500 C CA . GLU Q 1 8 ? 0.542 47.418 33.863 1.00 194.03 ? 8 GLU Q CA 1 +ATOM 30501 C C . GLU Q 1 8 ? 0.322 48.475 32.778 1.00 153.86 ? 8 GLU Q C 1 +ATOM 30502 O O . GLU Q 1 8 ? -0.791 48.714 32.329 1.00 130.03 ? 8 GLU Q O 1 +ATOM 30503 C CB . GLU Q 1 8 ? 0.227 46.017 33.341 1.00 231.64 ? 8 GLU Q CB 1 +ATOM 30504 C CG . GLU Q 1 8 ? 1.439 45.053 33.484 1.00 229.68 ? 8 GLU Q CG 1 +ATOM 30505 C CD . GLU Q 1 8 ? 1.232 43.907 34.478 1.00 218.24 ? 8 GLU Q CD 1 +ATOM 30506 O OE1 . GLU Q 1 8 ? 0.716 44.209 35.590 1.00 248.70 ? 8 GLU Q OE1 1 +ATOM 30507 O OE2 . GLU Q 1 8 ? 1.648 42.734 34.178 1.00 107.37 ? 8 GLU Q OE2 1 +ATOM 30508 N N . ALA Q 1 9 ? 1.413 49.122 32.387 1.00 148.17 ? 9 ALA Q N 1 +ATOM 30509 C CA . ALA Q 1 9 ? 1.432 50.040 31.257 1.00 134.87 ? 9 ALA Q CA 1 +ATOM 30510 C C . ALA Q 1 9 ? 1.939 49.328 29.999 1.00 141.22 ? 9 ALA Q C 1 +ATOM 30511 O O . ALA Q 1 9 ? 3.105 48.930 29.934 1.00 192.38 ? 9 ALA Q O 1 +ATOM 30512 C CB . ALA Q 1 9 ? 2.328 51.225 31.587 1.00 126.17 ? 9 ALA Q CB 1 +ATOM 30513 N N . ALA Q 1 10 ? 1.062 49.190 29.005 1.00 133.00 ? 10 ALA Q N 1 +ATOM 30514 C CA . ALA Q 1 10 ? 1.345 48.496 27.724 1.00 142.81 ? 10 ALA Q CA 1 +ATOM 30515 C C . ALA Q 1 10 ? 1.093 47.004 27.827 1.00 152.08 ? 10 ALA Q C 1 +ATOM 30516 O O . ALA Q 1 10 ? 1.060 46.461 28.944 1.00 129.51 ? 10 ALA Q O 1 +ATOM 30517 C CB . ALA Q 1 10 ? 2.759 48.771 27.209 1.00 114.62 ? 10 ALA Q CB 1 +ATOM 30518 N N . ARG Q 1 11 ? 0.892 46.371 26.661 1.00 145.39 ? 11 ARG Q N 1 +ATOM 30519 C CA . ARG Q 1 11 ? 0.482 44.975 26.587 1.00 141.56 ? 11 ARG Q CA 1 +ATOM 30520 C C . ARG Q 1 11 ? 1.618 44.095 26.094 1.00 132.69 ? 11 ARG Q C 1 +ATOM 30521 O O . ARG Q 1 11 ? 2.455 44.519 25.291 1.00 150.36 ? 11 ARG Q O 1 +ATOM 30522 C CB . ARG Q 1 11 ? -0.717 44.803 25.636 1.00 156.03 ? 11 ARG Q CB 1 +ATOM 30523 C CG . ARG Q 1 11 ? -0.399 45.037 24.168 1.00 163.73 ? 11 ARG Q CG 1 +ATOM 30524 C CD . ARG Q 1 11 ? -1.622 45.497 23.384 1.00 172.20 ? 11 ARG Q CD 1 +ATOM 30525 N NE . ARG Q 1 11 ? -1.431 46.838 22.838 1.00 190.19 ? 11 ARG Q NE 1 +ATOM 30526 C CZ . ARG Q 1 11 ? -2.303 47.443 22.038 1.00 207.28 ? 11 ARG Q CZ 1 +ATOM 30527 N NH1 . ARG Q 1 11 ? -3.442 46.843 21.722 1.00 230.22 ? 11 ARG Q NH1 1 +ATOM 30528 N NH2 . ARG Q 1 11 ? -2.050 48.659 21.567 1.00 211.84 ? 11 ARG Q NH2 1 +ATOM 30529 N N . PRO Q 1 12 ? 1.632 42.831 26.527 1.00 132.15 ? 12 PRO Q N 1 +ATOM 30530 C CA . PRO Q 1 12 ? 2.518 41.896 25.861 1.00 137.00 ? 12 PRO Q CA 1 +ATOM 30531 C C . PRO Q 1 12 ? 2.037 41.666 24.434 1.00 105.12 ? 12 PRO Q C 1 +ATOM 30532 O O . PRO Q 1 12 ? 0.937 41.146 24.221 1.00 118.61 ? 12 PRO Q O 1 +ATOM 30533 C CB . PRO Q 1 12 ? 2.391 40.610 26.698 1.00 166.93 ? 12 PRO Q CB 1 +ATOM 30534 C CG . PRO Q 1 12 ? 1.703 41.005 27.960 1.00 169.21 ? 12 PRO Q CG 1 +ATOM 30535 C CD . PRO Q 1 12 ? 0.851 42.183 27.588 1.00 145.72 ? 12 PRO Q CD 1 +ATOM 30536 N N . THR Q 1 13 ? 2.847 42.080 23.472 1.00 77.26 ? 13 THR Q N 1 +ATOM 30537 C CA . THR Q 1 13 ? 2.666 41.653 22.105 1.00 90.36 ? 13 THR Q CA 1 +ATOM 30538 C C . THR Q 1 13 ? 3.502 40.397 21.806 1.00 109.08 ? 13 THR Q C 1 +ATOM 30539 O O . THR Q 1 13 ? 4.470 40.133 22.512 1.00 143.22 ? 13 THR Q O 1 +ATOM 30540 C CB . THR Q 1 13 ? 3.079 42.780 21.151 1.00 85.75 ? 13 THR Q CB 1 +ATOM 30541 O OG1 . THR Q 1 13 ? 2.658 42.429 19.816 1.00 168.43 ? 13 THR Q OG1 1 +ATOM 30542 C CG2 . THR Q 1 13 ? 4.604 43.049 21.199 1.00 60.51 ? 13 THR Q CG2 1 +ATOM 30543 N N . LEU Q 1 14 ? 3.155 39.626 20.772 1.00 96.31 ? 14 LEU Q N 1 +ATOM 30544 C CA . LEU Q 1 14 ? 4.110 38.628 20.308 1.00 87.15 ? 14 LEU Q CA 1 +ATOM 30545 C C . LEU Q 1 14 ? 5.278 39.328 19.559 1.00 95.82 ? 14 LEU Q C 1 +ATOM 30546 O O . LEU Q 1 14 ? 5.169 40.487 19.221 1.00 93.35 ? 14 LEU Q O 1 +ATOM 30547 C CB . LEU Q 1 14 ? 3.471 37.509 19.503 1.00 66.06 ? 14 LEU Q CB 1 +ATOM 30548 C CG . LEU Q 1 14 ? 2.682 37.882 18.292 1.00 80.66 ? 14 LEU Q CG 1 +ATOM 30549 C CD1 . LEU Q 1 14 ? 2.822 36.819 17.213 1.00 99.84 ? 14 LEU Q CD1 1 +ATOM 30550 C CD2 . LEU Q 1 14 ? 1.244 38.012 18.707 1.00 107.66 ? 14 LEU Q CD2 1 +ATOM 30551 N N . MET Q 1 15 ? 6.447 38.690 19.495 1.00 118.63 ? 15 MET Q N 1 +ATOM 30552 C CA . MET Q 1 15 ? 7.718 39.426 19.382 1.00 106.20 ? 15 MET Q CA 1 +ATOM 30553 C C . MET Q 1 15 ? 7.810 40.051 18.003 1.00 82.23 ? 15 MET Q C 1 +ATOM 30554 O O . MET Q 1 15 ? 7.751 39.348 16.997 1.00 56.74 ? 15 MET Q O 1 +ATOM 30555 C CB . MET Q 1 15 ? 8.946 38.537 19.687 1.00 116.31 ? 15 MET Q CB 1 +ATOM 30556 C CG . MET Q 1 15 ? 10.123 39.326 20.245 1.00 102.45 ? 15 MET Q CG 1 +ATOM 30557 S SD . MET Q 1 15 ? 11.808 38.972 19.729 1.00 94.35 ? 15 MET Q SD 1 +ATOM 30558 C CE . MET Q 1 15 ? 11.729 37.883 18.326 1.00 82.94 ? 15 MET Q CE 1 +ATOM 30559 N N . PRO Q 1 16 ? 7.976 41.374 17.965 1.00 84.03 ? 16 PRO Q N 1 +ATOM 30560 C CA . PRO Q 1 16 ? 7.977 42.161 16.743 1.00 103.15 ? 16 PRO Q CA 1 +ATOM 30561 C C . PRO Q 1 16 ? 9.115 41.821 15.751 1.00 104.58 ? 16 PRO Q C 1 +ATOM 30562 O O . PRO Q 1 16 ? 10.085 42.561 15.615 1.00 76.57 ? 16 PRO Q O 1 +ATOM 30563 C CB . PRO Q 1 16 ? 8.101 43.605 17.256 1.00 103.72 ? 16 PRO Q CB 1 +ATOM 30564 C CG . PRO Q 1 16 ? 8.780 43.475 18.558 1.00 98.63 ? 16 PRO Q CG 1 +ATOM 30565 C CD . PRO Q 1 16 ? 8.245 42.207 19.145 1.00 86.15 ? 16 PRO Q CD 1 +ATOM 30566 N N . ARG Q 1 17 ? 8.898 40.775 14.964 1.00 107.29 ? 17 ARG Q N 1 +ATOM 30567 C CA . ARG Q 1 17 ? 9.766 40.453 13.832 1.00 90.82 ? 17 ARG Q CA 1 +ATOM 30568 C C . ARG Q 1 17 ? 9.306 41.213 12.589 1.00 99.17 ? 17 ARG Q C 1 +ATOM 30569 O O . ARG Q 1 17 ? 8.103 41.399 12.392 1.00 109.40 ? 17 ARG Q O 1 +ATOM 30570 C CB . ARG Q 1 17 ? 9.735 38.932 13.588 1.00 68.04 ? 17 ARG Q CB 1 +ATOM 30571 C CG . ARG Q 1 17 ? 10.730 38.170 14.436 1.00 65.63 ? 17 ARG Q CG 1 +ATOM 30572 C CD . ARG Q 1 17 ? 10.458 36.675 14.523 1.00 60.36 ? 17 ARG Q CD 1 +ATOM 30573 N NE . ARG Q 1 17 ? 9.397 36.389 15.477 1.00 75.50 ? 17 ARG Q NE 1 +ATOM 30574 C CZ . ARG Q 1 17 ? 8.882 35.183 15.679 1.00 104.36 ? 17 ARG Q CZ 1 +ATOM 30575 N NH1 . ARG Q 1 17 ? 9.374 34.144 15.007 1.00 120.02 ? 17 ARG Q NH1 1 +ATOM 30576 N NH2 . ARG Q 1 17 ? 7.880 35.014 16.559 1.00 121.34 ? 17 ARG Q NH2 1 +ATOM 30577 N N . ALA Q 1 18 ? 10.238 41.608 11.728 1.00 103.40 ? 18 ALA Q N 1 +ATOM 30578 C CA . ALA Q 1 18 ? 9.875 42.358 10.517 1.00 133.28 ? 18 ALA Q CA 1 +ATOM 30579 C C . ALA Q 1 18 ? 10.084 41.595 9.183 1.00 110.18 ? 18 ALA Q C 1 +ATOM 30580 O O . ALA Q 1 18 ? 9.446 40.570 8.940 1.00 65.93 ? 18 ALA Q O 1 +ATOM 30581 C CB . ALA Q 1 18 ? 10.600 43.695 10.501 1.00 167.22 ? 18 ALA Q CB 1 +ATOM 30582 N N . GLN Q 1 19 ? 10.949 42.119 8.319 1.00 110.70 ? 19 GLN Q N 1 +ATOM 30583 C CA . GLN Q 1 19 ? 10.932 41.745 6.911 1.00 128.76 ? 19 GLN Q CA 1 +ATOM 30584 C C . GLN Q 1 19 ? 11.440 40.317 6.700 1.00 135.20 ? 19 GLN Q C 1 +ATOM 30585 O O . GLN Q 1 19 ? 10.822 39.510 5.995 1.00 112.62 ? 19 GLN Q O 1 +ATOM 30586 C CB . GLN Q 1 19 ? 11.797 42.724 6.107 1.00 159.10 ? 19 GLN Q CB 1 +ATOM 30587 C CG . GLN Q 1 19 ? 11.747 42.508 4.599 1.00 190.83 ? 19 GLN Q CG 1 +ATOM 30588 C CD . GLN Q 1 19 ? 10.332 42.515 4.053 1.00 194.74 ? 19 GLN Q CD 1 +ATOM 30589 O OE1 . GLN Q 1 19 ? 9.659 43.549 4.067 1.00 216.72 ? 19 GLN Q OE1 1 +ATOM 30590 N NE2 . GLN Q 1 19 ? 9.867 41.359 3.578 1.00 164.96 ? 19 GLN Q NE2 1 +ATOM 30591 N N . SER Q 1 20 ? 12.598 40.035 7.303 1.00 152.18 ? 20 SER Q N 1 +ATOM 30592 C CA . SER Q 1 20 ? 13.194 38.697 7.329 1.00 123.86 ? 20 SER Q CA 1 +ATOM 30593 C C . SER Q 1 20 ? 12.139 37.622 7.637 1.00 111.24 ? 20 SER Q C 1 +ATOM 30594 O O . SER Q 1 20 ? 11.998 36.659 6.895 1.00 124.79 ? 20 SER Q O 1 +ATOM 30595 C CB . SER Q 1 20 ? 14.307 38.660 8.384 1.00 113.42 ? 20 SER Q CB 1 +ATOM 30596 O OG . SER Q 1 20 ? 15.215 39.736 8.217 1.00 83.31 ? 20 SER Q OG 1 +ATOM 30597 N N . TYR Q 1 21 ? 11.352 37.853 8.686 1.00 97.18 ? 21 TYR Q N 1 +ATOM 30598 C CA . TYR Q 1 21 ? 10.230 36.985 9.054 1.00 98.19 ? 21 TYR Q CA 1 +ATOM 30599 C C . TYR Q 1 21 ? 9.194 36.785 7.938 1.00 115.10 ? 21 TYR Q C 1 +ATOM 30600 O O . TYR Q 1 21 ? 8.836 35.657 7.607 1.00 96.94 ? 21 TYR Q O 1 +ATOM 30601 C CB . TYR Q 1 21 ? 9.506 37.564 10.273 1.00 110.67 ? 21 TYR Q CB 1 +ATOM 30602 C CG . TYR Q 1 21 ? 8.377 36.706 10.768 1.00 130.05 ? 21 TYR Q CG 1 +ATOM 30603 C CD1 . TYR Q 1 21 ? 8.653 35.513 11.458 1.00 195.55 ? 21 TYR Q CD1 1 +ATOM 30604 C CD2 . TYR Q 1 21 ? 7.049 37.048 10.544 1.00 75.66 ? 21 TYR Q CD2 1 +ATOM 30605 C CE1 . TYR Q 1 21 ? 7.645 34.686 11.910 1.00 166.33 ? 21 TYR Q CE1 1 +ATOM 30606 C CE2 . TYR Q 1 21 ? 6.040 36.230 11.011 1.00 93.03 ? 21 TYR Q CE2 1 +ATOM 30607 C CZ . TYR Q 1 21 ? 6.350 35.056 11.709 1.00 117.94 ? 21 TYR Q CZ 1 +ATOM 30608 O OH . TYR Q 1 21 ? 5.396 34.180 12.153 1.00 95.33 ? 21 TYR Q OH 1 +ATOM 30609 N N . LYS Q 1 22 ? 8.733 37.887 7.355 1.00 156.54 ? 22 LYS Q N 1 +ATOM 30610 C CA . LYS Q 1 22 ? 7.743 37.838 6.279 1.00 143.92 ? 22 LYS Q CA 1 +ATOM 30611 C C . LYS Q 1 22 ? 8.216 37.046 5.061 1.00 128.03 ? 22 LYS Q C 1 +ATOM 30612 O O . LYS Q 1 22 ? 7.450 36.284 4.479 1.00 100.40 ? 22 LYS Q O 1 +ATOM 30613 C CB . LYS Q 1 22 ? 7.386 39.256 5.835 1.00 163.55 ? 22 LYS Q CB 1 +ATOM 30614 C CG . LYS Q 1 22 ? 6.261 39.869 6.639 1.00 154.60 ? 22 LYS Q CG 1 +ATOM 30615 C CD . LYS Q 1 22 ? 4.902 39.382 6.118 1.00 116.71 ? 22 LYS Q CD 1 +ATOM 30616 C CE . LYS Q 1 22 ? 4.250 40.468 5.259 1.00 131.99 ? 22 LYS Q CE 1 +ATOM 30617 N NZ . LYS Q 1 22 ? 3.907 41.677 6.061 1.00 155.97 ? 22 LYS Q NZ 1 +ATOM 30618 N N . ASP Q 1 23 ? 9.482 37.241 4.686 1.00 126.76 ? 23 ASP Q N 1 +ATOM 30619 C CA . ASP Q 1 23 ? 10.122 36.429 3.651 1.00 120.99 ? 23 ASP Q CA 1 +ATOM 30620 C C . ASP Q 1 23 ? 10.208 34.949 4.041 1.00 134.57 ? 23 ASP Q C 1 +ATOM 30621 O O . ASP Q 1 23 ? 9.860 34.061 3.258 1.00 163.15 ? 23 ASP Q O 1 +ATOM 30622 C CB . ASP Q 1 23 ? 11.536 36.939 3.372 1.00 111.32 ? 23 ASP Q CB 1 +ATOM 30623 C CG . ASP Q 1 23 ? 11.534 38.300 2.770 1.00 118.33 ? 23 ASP Q CG 1 +ATOM 30624 O OD1 . ASP Q 1 23 ? 10.690 38.530 1.878 1.00 156.76 ? 23 ASP Q OD1 1 +ATOM 30625 O OD2 . ASP Q 1 23 ? 12.401 39.114 3.131 1.00 107.63 ? 23 ASP Q OD2 1 +ATOM 30626 N N . LEU Q 1 24 ? 10.633 34.702 5.275 1.00 144.73 ? 24 LEU Q N 1 +ATOM 30627 C CA . LEU Q 1 24 ? 10.859 33.346 5.782 1.00 134.70 ? 24 LEU Q CA 1 +ATOM 30628 C C . LEU Q 1 24 ? 9.569 32.510 5.838 1.00 138.94 ? 24 LEU Q C 1 +ATOM 30629 O O . LEU Q 1 24 ? 9.587 31.298 5.604 1.00 141.97 ? 24 LEU Q O 1 +ATOM 30630 C CB . LEU Q 1 24 ? 11.482 33.430 7.186 1.00 136.53 ? 24 LEU Q CB 1 +ATOM 30631 C CG . LEU Q 1 24 ? 11.818 32.122 7.902 1.00 118.20 ? 24 LEU Q CG 1 +ATOM 30632 C CD1 . LEU Q 1 24 ? 13.200 31.621 7.480 1.00 139.15 ? 24 LEU Q CD1 1 +ATOM 30633 C CD2 . LEU Q 1 24 ? 11.746 32.309 9.410 1.00 95.47 ? 24 LEU Q CD2 1 +ATOM 30634 N N . THR Q 1 25 ? 8.457 33.160 6.183 1.00 149.14 ? 25 THR Q N 1 +ATOM 30635 C CA . THR Q 1 25 ? 7.168 32.473 6.325 1.00 136.19 ? 25 THR Q CA 1 +ATOM 30636 C C . THR Q 1 25 ? 6.564 32.112 4.970 1.00 121.80 ? 25 THR Q C 1 +ATOM 30637 O O . THR Q 1 25 ? 6.109 30.993 4.765 1.00 62.11 ? 25 THR Q O 1 +ATOM 30638 C CB . THR Q 1 25 ? 6.164 33.334 7.132 1.00 178.71 ? 25 THR Q CB 1 +ATOM 30639 O OG1 . THR Q 1 25 ? 6.182 34.691 6.660 1.00 210.01 ? 25 THR Q OG1 1 +ATOM 30640 C CG2 . THR Q 1 25 ? 6.526 33.321 8.609 1.00 201.34 ? 25 THR Q CG2 1 +ATOM 30641 N N . HIS Q 1 26 ? 6.558 33.088 4.055 1.00 172.87 ? 26 HIS Q N 1 +ATOM 30642 C CA . HIS Q 1 26 ? 5.944 32.939 2.725 1.00 142.37 ? 26 HIS Q CA 1 +ATOM 30643 C C . HIS Q 1 26 ? 6.906 32.263 1.731 1.00 92.38 ? 26 HIS Q C 1 +ATOM 30644 O O . HIS Q 1 26 ? 6.957 32.615 0.568 1.00 71.03 ? 26 HIS Q O 1 +ATOM 30645 C CB . HIS Q 1 26 ? 5.467 34.319 2.206 1.00 152.26 ? 26 HIS Q CB 1 +ATOM 30646 C CG . HIS Q 1 26 ? 4.372 34.941 3.036 1.00 168.70 ? 26 HIS Q CG 1 +ATOM 30647 N ND1 . HIS Q 1 26 ? 4.585 35.440 4.305 1.00 192.38 ? 26 HIS Q ND1 1 +ATOM 30648 C CD2 . HIS Q 1 26 ? 3.058 35.145 2.775 1.00 167.64 ? 26 HIS Q CD2 1 +ATOM 30649 C CE1 . HIS Q 1 26 ? 3.449 35.903 4.797 1.00 157.76 ? 26 HIS Q CE1 1 +ATOM 30650 N NE2 . HIS Q 1 26 ? 2.509 35.748 3.885 1.00 146.10 ? 26 HIS Q NE2 1 +ATOM 30651 N N . LEU Q 1 27 ? 7.699 31.328 2.216 1.00 80.31 ? 27 LEU Q N 1 +ATOM 30652 C CA . LEU Q 1 27 ? 8.578 30.574 1.348 1.00 97.94 ? 27 LEU Q CA 1 +ATOM 30653 C C . LEU Q 1 27 ? 7.829 29.346 0.829 1.00 104.56 ? 27 LEU Q C 1 +ATOM 30654 O O . LEU Q 1 27 ? 7.158 28.658 1.597 1.00 82.12 ? 27 LEU Q O 1 +ATOM 30655 C CB . LEU Q 1 27 ? 9.840 30.126 2.103 1.00 130.49 ? 27 LEU Q CB 1 +ATOM 30656 C CG . LEU Q 1 27 ? 11.010 31.112 2.089 1.00 142.17 ? 27 LEU Q CG 1 +ATOM 30657 C CD1 . LEU Q 1 27 ? 12.071 30.723 3.112 1.00 142.31 ? 27 LEU Q CD1 1 +ATOM 30658 C CD2 . LEU Q 1 27 ? 11.624 31.209 0.696 1.00 149.04 ? 27 LEU Q CD2 1 +ATOM 30659 N N . PRO Q 1 28 ? 7.980 29.039 -0.472 1.00 118.27 ? 28 PRO Q N 1 +ATOM 30660 C CA . PRO Q 1 28 ? 7.292 27.896 -1.102 1.00 104.48 ? 28 PRO Q CA 1 +ATOM 30661 C C . PRO Q 1 28 ? 7.702 26.594 -0.469 1.00 130.75 ? 28 PRO Q C 1 +ATOM 30662 O O . PRO Q 1 28 ? 8.894 26.354 -0.302 1.00 195.89 ? 28 PRO Q O 1 +ATOM 30663 C CB . PRO Q 1 28 ? 7.779 27.944 -2.539 1.00 103.47 ? 28 PRO Q CB 1 +ATOM 30664 C CG . PRO Q 1 28 ? 9.075 28.709 -2.489 1.00 104.07 ? 28 PRO Q CG 1 +ATOM 30665 C CD . PRO Q 1 28 ? 8.897 29.725 -1.404 1.00 119.24 ? 28 PRO Q CD 1 +ATOM 30666 N N . ALA Q 1 29 ? 6.736 25.770 -0.082 1.00 147.44 ? 29 ALA Q N 1 +ATOM 30667 C CA . ALA Q 1 29 ? 7.016 24.622 0.793 1.00 145.19 ? 29 ALA Q CA 1 +ATOM 30668 C C . ALA Q 1 29 ? 7.736 23.481 0.040 1.00 140.48 ? 29 ALA Q C 1 +ATOM 30669 O O . ALA Q 1 29 ? 7.560 23.316 -1.179 1.00 112.52 ? 29 ALA Q O 1 +ATOM 30670 C CB . ALA Q 1 29 ? 5.733 24.118 1.440 1.00 137.83 ? 29 ALA Q CB 1 +ATOM 30671 N N . PRO Q 1 30 ? 8.615 22.741 0.751 1.00 126.57 ? 30 PRO Q N 1 +ATOM 30672 C CA . PRO Q 1 30 ? 9.319 21.575 0.187 1.00 109.08 ? 30 PRO Q CA 1 +ATOM 30673 C C . PRO Q 1 30 ? 8.419 20.342 0.093 1.00 93.22 ? 30 PRO Q C 1 +ATOM 30674 O O . PRO Q 1 30 ? 7.258 20.398 0.532 1.00 113.43 ? 30 PRO Q O 1 +ATOM 30675 C CB . PRO Q 1 30 ? 10.398 21.302 1.220 1.00 107.47 ? 30 PRO Q CB 1 +ATOM 30676 C CG . PRO Q 1 30 ? 9.810 21.766 2.511 1.00 92.29 ? 30 PRO Q CG 1 +ATOM 30677 C CD . PRO Q 1 30 ? 8.912 22.923 2.186 1.00 107.26 ? 30 PRO Q CD 1 +ATOM 30678 N N . THR Q 1 31 ? 8.940 19.247 -0.467 1.00 76.51 ? 31 THR Q N 1 +ATOM 30679 C CA . THR Q 1 31 ? 8.130 18.030 -0.685 1.00 98.69 ? 31 THR Q CA 1 +ATOM 30680 C C . THR Q 1 31 ? 7.790 17.344 0.630 1.00 99.06 ? 31 THR Q C 1 +ATOM 30681 O O . THR Q 1 31 ? 6.780 16.650 0.737 1.00 109.99 ? 31 THR Q O 1 +ATOM 30682 C CB . THR Q 1 31 ? 8.812 17.005 -1.632 1.00 111.21 ? 31 THR Q CB 1 +ATOM 30683 O OG1 . THR Q 1 31 ? 10.146 16.734 -1.195 1.00 121.77 ? 31 THR Q OG1 1 +ATOM 30684 C CG2 . THR Q 1 31 ? 8.843 17.512 -3.074 1.00 110.48 ? 31 THR Q CG2 1 +ATOM 30685 N N . GLY Q 1 32 ? 8.634 17.551 1.630 1.00 115.90 ? 32 GLY Q N 1 +ATOM 30686 C CA . GLY Q 1 32 ? 8.305 17.197 3.004 1.00 134.59 ? 32 GLY Q CA 1 +ATOM 30687 C C . GLY Q 1 32 ? 9.128 18.085 3.913 1.00 140.12 ? 32 GLY Q C 1 +ATOM 30688 O O . GLY Q 1 32 ? 10.220 18.511 3.523 1.00 156.58 ? 32 GLY Q O 1 +ATOM 30689 N N . LYS Q 1 33 ? 8.660 18.315 5.138 1.00 110.34 ? 33 LYS Q N 1 +ATOM 30690 C CA . LYS Q 1 33 ? 9.512 18.982 6.108 1.00 111.60 ? 33 LYS Q CA 1 +ATOM 30691 C C . LYS Q 1 33 ? 10.784 18.155 6.462 1.00 145.60 ? 33 LYS Q C 1 +ATOM 30692 O O . LYS Q 1 33 ? 10.762 16.919 6.451 1.00 131.66 ? 33 LYS Q O 1 +ATOM 30693 C CB . LYS Q 1 33 ? 8.737 19.341 7.366 1.00 75.85 ? 33 LYS Q CB 1 +ATOM 30694 C CG . LYS Q 1 33 ? 8.052 20.667 7.284 1.00 72.66 ? 33 LYS Q CG 1 +ATOM 30695 C CD . LYS Q 1 33 ? 7.151 20.878 8.478 1.00 71.87 ? 33 LYS Q CD 1 +ATOM 30696 C CE . LYS Q 1 33 ? 6.029 21.834 8.143 1.00 83.23 ? 33 LYS Q CE 1 +ATOM 30697 N NZ . LYS Q 1 33 ? 5.038 21.939 9.232 1.00 85.86 ? 33 LYS Q NZ 1 +ATOM 30698 N N . ILE Q 1 34 ? 11.880 18.842 6.798 1.00 156.20 ? 34 ILE Q N 1 +ATOM 30699 C CA . ILE Q 1 34 ? 13.140 18.176 7.117 1.00 144.01 ? 34 ILE Q CA 1 +ATOM 30700 C C . ILE Q 1 34 ? 13.370 18.241 8.644 1.00 143.12 ? 34 ILE Q C 1 +ATOM 30701 O O . ILE Q 1 34 ? 12.964 19.207 9.308 1.00 80.19 ? 34 ILE Q O 1 +ATOM 30702 C CB . ILE Q 1 34 ? 14.305 18.776 6.283 1.00 137.54 ? 34 ILE Q CB 1 +ATOM 30703 C CG1 . ILE Q 1 34 ? 14.094 18.479 4.801 1.00 120.83 ? 34 ILE Q CG1 1 +ATOM 30704 C CG2 . ILE Q 1 34 ? 15.658 18.205 6.682 1.00 161.53 ? 34 ILE Q CG2 1 +ATOM 30705 C CD1 . ILE Q 1 34 ? 13.936 19.725 3.957 1.00 135.06 ? 34 ILE Q CD1 1 +ATOM 30706 N N . PHE Q 1 35 ? 13.891 17.140 9.191 1.00 137.44 ? 35 PHE Q N 1 +ATOM 30707 C CA . PHE Q 1 35 ? 14.182 17.009 10.608 1.00 124.21 ? 35 PHE Q CA 1 +ATOM 30708 C C . PHE Q 1 35 ? 15.523 17.643 10.965 1.00 126.96 ? 35 PHE Q C 1 +ATOM 30709 O O . PHE Q 1 35 ? 16.533 17.287 10.386 1.00 125.97 ? 35 PHE Q O 1 +ATOM 30710 C CB . PHE Q 1 35 ? 14.259 15.536 10.953 1.00 101.87 ? 35 PHE Q CB 1 +ATOM 30711 C CG . PHE Q 1 35 ? 12.928 14.910 11.220 1.00 95.11 ? 35 PHE Q CG 1 +ATOM 30712 C CD1 . PHE Q 1 35 ? 11.990 15.530 12.052 1.00 97.45 ? 35 PHE Q CD1 1 +ATOM 30713 C CD2 . PHE Q 1 35 ? 12.681 13.632 10.793 1.00 108.45 ? 35 PHE Q CD2 1 +ATOM 30714 C CE1 . PHE Q 1 35 ? 10.788 14.915 12.361 1.00 84.18 ? 35 PHE Q CE1 1 +ATOM 30715 C CE2 . PHE Q 1 35 ? 11.491 12.997 11.125 1.00 115.50 ? 35 PHE Q CE2 1 +ATOM 30716 C CZ . PHE Q 1 35 ? 10.541 13.642 11.905 1.00 92.73 ? 35 PHE Q CZ 1 +ATOM 30717 N N . VAL Q 1 36 ? 15.533 18.565 11.928 1.00 113.14 ? 36 VAL Q N 1 +ATOM 30718 C CA . VAL Q 1 36 ? 16.750 19.330 12.224 1.00 84.88 ? 36 VAL Q CA 1 +ATOM 30719 C C . VAL Q 1 36 ? 17.047 19.429 13.707 1.00 60.62 ? 36 VAL Q C 1 +ATOM 30720 O O . VAL Q 1 36 ? 16.144 19.362 14.533 1.00 50.31 ? 36 VAL Q O 1 +ATOM 30721 C CB . VAL Q 1 36 ? 16.665 20.766 11.665 1.00 90.57 ? 36 VAL Q CB 1 +ATOM 30722 C CG1 . VAL Q 1 36 ? 15.753 21.645 12.524 1.00 81.59 ? 36 VAL Q CG1 1 +ATOM 30723 C CG2 . VAL Q 1 36 ? 18.052 21.351 11.579 1.00 86.72 ? 36 VAL Q CG2 1 +ATOM 30724 N N . SER Q 1 37 ? 18.322 19.553 14.028 1.00 56.93 ? 37 SER Q N 1 +ATOM 30725 C CA . SER Q 1 37 ? 18.752 19.574 15.411 1.00 74.20 ? 37 SER Q CA 1 +ATOM 30726 C C . SER Q 1 37 ? 19.575 20.800 15.616 1.00 70.57 ? 37 SER Q C 1 +ATOM 30727 O O . SER Q 1 37 ? 20.486 21.061 14.853 1.00 50.36 ? 37 SER Q O 1 +ATOM 30728 C CB . SER Q 1 37 ? 19.632 18.362 15.741 1.00 85.25 ? 37 SER Q CB 1 +ATOM 30729 O OG . SER Q 1 37 ? 18.876 17.166 15.882 1.00 140.91 ? 37 SER Q OG 1 +ATOM 30730 N N . VAL Q 1 38 ? 19.279 21.560 16.662 1.00 111.10 ? 38 VAL Q N 1 +ATOM 30731 C CA . VAL Q 1 38 ? 20.196 22.639 17.078 1.00 115.86 ? 38 VAL Q CA 1 +ATOM 30732 C C . VAL Q 1 38 ? 20.642 22.444 18.522 1.00 90.65 ? 38 VAL Q C 1 +ATOM 30733 O O . VAL Q 1 38 ? 19.798 22.405 19.421 1.00 95.59 ? 38 VAL Q O 1 +ATOM 30734 C CB . VAL Q 1 38 ? 19.542 24.032 16.988 1.00 143.37 ? 38 VAL Q CB 1 +ATOM 30735 C CG1 . VAL Q 1 38 ? 20.519 25.081 17.462 1.00 130.92 ? 38 VAL Q CG1 1 +ATOM 30736 C CG2 . VAL Q 1 38 ? 19.079 24.340 15.569 1.00 192.80 ? 38 VAL Q CG2 1 +ATOM 30737 N N . TYR Q 1 39 ? 21.946 22.265 18.716 1.00 82.54 ? 39 TYR Q N 1 +ATOM 30738 C CA . TYR Q 1 39 ? 22.512 21.957 20.031 1.00 81.40 ? 39 TYR Q CA 1 +ATOM 30739 C C . TYR Q 1 39 ? 22.864 23.291 20.703 1.00 83.07 ? 39 TYR Q C 1 +ATOM 30740 O O . TYR Q 1 39 ? 22.437 23.566 21.816 1.00 89.31 ? 39 TYR Q O 1 +ATOM 30741 C CB . TYR Q 1 39 ? 23.746 20.988 19.908 1.00 67.56 ? 39 TYR Q CB 1 +ATOM 30742 C CG . TYR Q 1 39 ? 23.401 19.477 19.878 1.00 53.20 ? 39 TYR Q CG 1 +ATOM 30743 C CD1 . TYR Q 1 39 ? 22.840 18.892 18.756 1.00 50.83 ? 39 TYR Q CD1 1 +ATOM 30744 C CD2 . TYR Q 1 39 ? 23.483 18.692 21.022 1.00 53.17 ? 39 TYR Q CD2 1 +ATOM 30745 C CE1 . TYR Q 1 39 ? 22.390 17.563 18.761 1.00 43.62 ? 39 TYR Q CE1 1 +ATOM 30746 C CE2 . TYR Q 1 39 ? 23.018 17.381 21.046 1.00 44.70 ? 39 TYR Q CE2 1 +ATOM 30747 C CZ . TYR Q 1 39 ? 22.465 16.809 19.902 1.00 40.25 ? 39 TYR Q CZ 1 +ATOM 30748 O OH . TYR Q 1 39 ? 22.146 15.459 19.872 1.00 25.24 ? 39 TYR Q OH 1 +ATOM 30749 N N . ASN Q 1 40 ? 23.632 24.137 20.019 1.00 87.55 ? 40 ASN Q N 1 +ATOM 30750 C CA . ASN Q 1 40 ? 24.051 25.422 20.602 1.00 82.79 ? 40 ASN Q CA 1 +ATOM 30751 C C . ASN Q 1 40 ? 24.671 26.405 19.600 1.00 98.82 ? 40 ASN Q C 1 +ATOM 30752 O O . ASN Q 1 40 ? 25.552 26.036 18.810 1.00 141.75 ? 40 ASN Q O 1 +ATOM 30753 C CB . ASN Q 1 40 ? 25.062 25.169 21.720 1.00 89.82 ? 40 ASN Q CB 1 +ATOM 30754 C CG . ASN Q 1 40 ? 25.204 26.349 22.663 1.00 108.59 ? 40 ASN Q CG 1 +ATOM 30755 O OD1 . ASN Q 1 40 ? 26.254 26.980 22.722 1.00 82.10 ? 40 ASN Q OD1 1 +ATOM 30756 N ND2 . ASN Q 1 40 ? 24.120 26.692 23.357 1.00 136.88 ? 40 ASN Q ND2 1 +ATOM 30757 N N . ILE Q 1 41 ? 24.210 27.656 19.632 1.00 94.67 ? 41 ILE Q N 1 +ATOM 30758 C CA . ILE Q 1 41 ? 24.875 28.749 18.910 1.00 103.32 ? 41 ILE Q CA 1 +ATOM 30759 C C . ILE Q 1 41 ? 25.427 29.793 19.884 1.00 90.44 ? 41 ILE Q C 1 +ATOM 30760 O O . ILE Q 1 41 ? 24.662 30.381 20.645 1.00 115.14 ? 41 ILE Q O 1 +ATOM 30761 C CB . ILE Q 1 41 ? 23.915 29.442 17.935 1.00 92.50 ? 41 ILE Q CB 1 +ATOM 30762 C CG1 . ILE Q 1 41 ? 23.782 28.635 16.635 1.00 100.93 ? 41 ILE Q CG1 1 +ATOM 30763 C CG2 . ILE Q 1 41 ? 24.478 30.799 17.541 1.00 105.70 ? 41 ILE Q CG2 1 +ATOM 30764 C CD1 . ILE Q 1 41 ? 23.009 27.342 16.742 1.00 102.61 ? 41 ILE Q CD1 1 +ATOM 30765 N N . GLN Q 1 42 ? 26.747 29.969 19.912 1.00 74.36 ? 42 GLN Q N 1 +ATOM 30766 C CA . GLN Q 1 42 ? 27.395 30.701 21.012 1.00 92.50 ? 42 GLN Q CA 1 +ATOM 30767 C C . GLN Q 1 42 ? 27.519 32.169 20.705 1.00 74.27 ? 42 GLN Q C 1 +ATOM 30768 O O . GLN Q 1 42 ? 27.562 32.552 19.553 1.00 92.03 ? 42 GLN Q O 1 +ATOM 30769 C CB . GLN Q 1 42 ? 28.796 30.147 21.323 1.00 125.04 ? 42 GLN Q CB 1 +ATOM 30770 C CG . GLN Q 1 42 ? 28.809 28.732 21.882 1.00 148.88 ? 42 GLN Q CG 1 +ATOM 30771 C CD . GLN Q 1 42 ? 29.559 27.758 20.984 1.00 178.72 ? 42 GLN Q CD 1 +ATOM 30772 O OE1 . GLN Q 1 42 ? 30.784 27.609 21.097 1.00 214.04 ? 42 GLN Q OE1 1 +ATOM 30773 N NE2 . GLN Q 1 42 ? 28.838 27.117 20.057 1.00 147.21 ? 42 GLN Q NE2 1 +ATOM 30774 N N . ASP Q 1 43 ? 27.594 32.980 21.758 1.00 69.17 ? 43 ASP Q N 1 +ATOM 30775 C CA . ASP Q 1 43 ? 27.989 34.375 21.658 1.00 60.20 ? 43 ASP Q CA 1 +ATOM 30776 C C . ASP Q 1 43 ? 29.525 34.514 21.465 1.00 65.95 ? 43 ASP Q C 1 +ATOM 30777 O O . ASP Q 1 43 ? 30.219 35.028 22.355 1.00 72.96 ? 43 ASP Q O 1 +ATOM 30778 C CB . ASP Q 1 43 ? 27.543 35.127 22.913 1.00 52.13 ? 43 ASP Q CB 1 +ATOM 30779 C CG . ASP Q 1 43 ? 27.720 36.650 22.781 1.00 63.28 ? 43 ASP Q CG 1 +ATOM 30780 O OD1 . ASP Q 1 43 ? 27.277 37.201 21.764 1.00 56.76 ? 43 ASP Q OD1 1 +ATOM 30781 O OD2 . ASP Q 1 43 ? 28.305 37.310 23.682 1.00 73.51 ? 43 ASP Q OD2 1 +ATOM 30782 N N . GLU Q 1 44 ? 30.046 34.021 20.337 1.00 57.67 ? 44 GLU Q N 1 +ATOM 30783 C CA . GLU Q 1 44 ? 31.475 34.015 20.075 1.00 57.13 ? 44 GLU Q CA 1 +ATOM 30784 C C . GLU Q 1 44 ? 32.005 35.430 19.832 1.00 51.06 ? 44 GLU Q C 1 +ATOM 30785 O O . GLU Q 1 44 ? 33.166 35.614 19.398 1.00 63.06 ? 44 GLU Q O 1 +ATOM 30786 C CB . GLU Q 1 44 ? 31.813 33.100 18.883 1.00 64.94 ? 44 GLU Q CB 1 +ATOM 30787 C CG . GLU Q 1 44 ? 32.063 31.626 19.234 1.00 91.49 ? 44 GLU Q CG 1 +ATOM 30788 C CD . GLU Q 1 44 ? 32.363 30.720 18.015 1.00 126.21 ? 44 GLU Q CD 1 +ATOM 30789 O OE1 . GLU Q 1 44 ? 33.170 31.084 17.117 1.00 171.27 ? 44 GLU Q OE1 1 +ATOM 30790 O OE2 . GLU Q 1 44 ? 31.823 29.585 17.957 1.00 150.73 ? 44 GLU Q OE2 1 +ATOM 30791 N N . THR Q 1 45 ? 31.220 36.432 20.216 1.00 53.11 ? 45 THR Q N 1 +ATOM 30792 C CA . THR Q 1 45 ? 31.531 37.837 19.886 1.00 80.14 ? 45 THR Q CA 1 +ATOM 30793 C C . THR Q 1 45 ? 32.666 38.441 20.716 1.00 95.82 ? 45 THR Q C 1 +ATOM 30794 O O . THR Q 1 45 ? 33.481 39.200 20.206 1.00 67.59 ? 45 THR Q O 1 +ATOM 30795 C CB . THR Q 1 45 ? 30.271 38.733 19.949 1.00 95.40 ? 45 THR Q CB 1 +ATOM 30796 O OG1 . THR Q 1 45 ? 30.532 39.994 19.331 1.00 136.62 ? 45 THR Q OG1 1 +ATOM 30797 C CG2 . THR Q 1 45 ? 29.788 38.994 21.388 1.00 77.45 ? 45 THR Q CG2 1 +ATOM 30798 N N . GLY Q 1 46 ? 32.687 38.145 22.014 1.00 116.82 ? 46 GLY Q N 1 +ATOM 30799 C CA . GLY Q 1 46 ? 33.800 38.576 22.898 1.00 86.51 ? 46 GLY Q CA 1 +ATOM 30800 C C . GLY Q 1 46 ? 33.599 39.957 23.522 1.00 68.71 ? 46 GLY Q C 1 +ATOM 30801 O O . GLY Q 1 46 ? 34.519 40.613 23.999 1.00 45.91 ? 46 GLY Q O 1 +ATOM 30802 N N . GLN Q 1 47 ? 32.358 40.381 23.603 1.00 72.13 ? 47 GLN Q N 1 +ATOM 30803 C CA . GLN Q 1 47 ? 32.142 41.762 23.788 1.00 82.73 ? 47 GLN Q CA 1 +ATOM 30804 C C . GLN Q 1 47 ? 31.109 42.039 24.854 1.00 89.09 ? 47 GLN Q C 1 +ATOM 30805 O O . GLN Q 1 47 ? 30.082 41.361 24.953 1.00 57.61 ? 47 GLN Q O 1 +ATOM 30806 C CB . GLN Q 1 47 ? 31.760 42.370 22.473 1.00 78.92 ? 47 GLN Q CB 1 +ATOM 30807 C CG . GLN Q 1 47 ? 32.903 42.367 21.438 1.00 77.33 ? 47 GLN Q CG 1 +ATOM 30808 C CD . GLN Q 1 47 ? 34.192 42.952 21.930 1.00 58.79 ? 47 GLN Q CD 1 +ATOM 30809 O OE1 . GLN Q 1 47 ? 34.272 44.142 22.191 1.00 74.29 ? 47 GLN Q OE1 1 +ATOM 30810 N NE2 . GLN Q 1 47 ? 35.160 42.120 22.157 1.00 59.84 ? 47 GLN Q NE2 1 +ATOM 30811 N N . PHE Q 1 48 ? 31.449 43.029 25.676 1.00 100.09 ? 48 PHE Q N 1 +ATOM 30812 C CA . PHE Q 1 48 ? 30.600 43.483 26.762 1.00 87.73 ? 48 PHE Q CA 1 +ATOM 30813 C C . PHE Q 1 48 ? 30.349 44.971 26.655 1.00 89.79 ? 48 PHE Q C 1 +ATOM 30814 O O . PHE Q 1 48 ? 30.992 45.692 25.867 1.00 108.13 ? 48 PHE Q O 1 +ATOM 30815 C CB . PHE Q 1 48 ? 31.267 43.226 28.105 1.00 96.73 ? 48 PHE Q CB 1 +ATOM 30816 C CG . PHE Q 1 48 ? 31.426 41.798 28.421 1.00 77.54 ? 48 PHE Q CG 1 +ATOM 30817 C CD1 . PHE Q 1 48 ? 32.455 41.082 27.805 1.00 67.66 ? 48 PHE Q CD1 1 +ATOM 30818 C CD2 . PHE Q 1 48 ? 30.579 41.189 29.345 1.00 45.35 ? 48 PHE Q CD2 1 +ATOM 30819 C CE1 . PHE Q 1 48 ? 32.567 39.745 28.018 1.00 64.64 ? 48 PHE Q CE1 1 +ATOM 30820 C CE2 . PHE Q 1 48 ? 30.723 39.880 29.616 1.00 44.61 ? 48 PHE Q CE2 1 +ATOM 30821 C CZ . PHE Q 1 48 ? 31.699 39.141 28.922 1.00 68.52 ? 48 PHE Q CZ 1 +ATOM 30822 N N . LYS Q 1 49 ? 29.395 45.431 27.454 1.00 89.66 ? 49 LYS Q N 1 +ATOM 30823 C CA . LYS Q 1 49 ? 28.938 46.810 27.373 1.00 103.66 ? 49 LYS Q CA 1 +ATOM 30824 C C . LYS Q 1 49 ? 29.910 47.668 28.125 1.00 122.09 ? 49 LYS Q C 1 +ATOM 30825 O O . LYS Q 1 49 ? 30.508 47.220 29.113 1.00 173.98 ? 49 LYS Q O 1 +ATOM 30826 C CB . LYS Q 1 49 ? 27.520 46.968 27.926 1.00 96.83 ? 49 LYS Q CB 1 +ATOM 30827 C CG . LYS Q 1 49 ? 26.485 46.271 27.040 1.00 108.39 ? 49 LYS Q CG 1 +ATOM 30828 C CD . LYS Q 1 49 ? 25.021 46.528 27.353 1.00 108.43 ? 49 LYS Q CD 1 +ATOM 30829 C CE . LYS Q 1 49 ? 24.194 45.862 26.244 1.00 117.90 ? 49 LYS Q CE 1 +ATOM 30830 N NZ . LYS Q 1 49 ? 22.725 46.044 26.346 1.00 134.34 ? 49 LYS Q NZ 1 +ATOM 30831 N N . PRO Q 1 50 ? 30.113 48.894 27.629 1.00 119.30 ? 50 PRO Q N 1 +ATOM 30832 C CA . PRO Q 1 50 ? 31.032 49.813 28.272 1.00 132.51 ? 50 PRO Q CA 1 +ATOM 30833 C C . PRO Q 1 50 ? 30.419 50.484 29.516 1.00 118.85 ? 50 PRO Q C 1 +ATOM 30834 O O . PRO Q 1 50 ? 29.197 50.423 29.736 1.00 51.98 ? 50 PRO Q O 1 +ATOM 30835 C CB . PRO Q 1 50 ? 31.309 50.845 27.166 1.00 150.07 ? 50 PRO Q CB 1 +ATOM 30836 C CG . PRO Q 1 50 ? 30.075 50.834 26.319 1.00 111.81 ? 50 PRO Q CG 1 +ATOM 30837 C CD . PRO Q 1 50 ? 29.567 49.433 26.366 1.00 100.14 ? 50 PRO Q CD 1 +ATOM 30838 N N . TYR Q 1 51 ? 31.277 51.154 30.285 1.00 111.01 ? 51 TYR Q N 1 +ATOM 30839 C CA . TYR Q 1 51 ? 30.813 51.991 31.363 1.00 97.49 ? 51 TYR Q CA 1 +ATOM 30840 C C . TYR Q 1 51 ? 29.739 52.929 30.863 1.00 94.37 ? 51 TYR Q C 1 +ATOM 30841 O O . TYR Q 1 51 ? 29.881 53.508 29.772 1.00 113.51 ? 51 TYR Q O 1 +ATOM 30842 C CB . TYR Q 1 51 ? 31.962 52.808 31.952 1.00 99.42 ? 51 TYR Q CB 1 +ATOM 30843 C CG . TYR Q 1 51 ? 31.582 53.408 33.294 1.00 104.85 ? 51 TYR Q CG 1 +ATOM 30844 C CD1 . TYR Q 1 51 ? 31.719 52.670 34.457 1.00 105.80 ? 51 TYR Q CD1 1 +ATOM 30845 C CD2 . TYR Q 1 51 ? 31.068 54.689 33.397 1.00 119.57 ? 51 TYR Q CD2 1 +ATOM 30846 C CE1 . TYR Q 1 51 ? 31.361 53.179 35.685 1.00 96.00 ? 51 TYR Q CE1 1 +ATOM 30847 C CE2 . TYR Q 1 51 ? 30.741 55.226 34.642 1.00 116.65 ? 51 TYR Q CE2 1 +ATOM 30848 C CZ . TYR Q 1 51 ? 30.860 54.436 35.772 1.00 104.67 ? 51 TYR Q CZ 1 +ATOM 30849 O OH . TYR Q 1 51 ? 30.531 54.894 37.022 1.00 137.97 ? 51 TYR Q OH 1 +ATOM 30850 N N . PRO Q 1 52 ? 28.653 53.099 31.643 1.00 91.61 ? 52 PRO Q N 1 +ATOM 30851 C CA . PRO Q 1 52 ? 28.383 52.611 32.991 1.00 87.17 ? 52 PRO Q CA 1 +ATOM 30852 C C . PRO Q 1 52 ? 27.690 51.263 33.126 1.00 116.72 ? 52 PRO Q C 1 +ATOM 30853 O O . PRO Q 1 52 ? 27.103 50.999 34.187 1.00 138.88 ? 52 PRO Q O 1 +ATOM 30854 C CB . PRO Q 1 52 ? 27.480 53.700 33.554 1.00 90.47 ? 52 PRO Q CB 1 +ATOM 30855 C CG . PRO Q 1 52 ? 26.675 54.154 32.365 1.00 99.55 ? 52 PRO Q CG 1 +ATOM 30856 C CD . PRO Q 1 52 ? 27.599 54.034 31.180 1.00 104.33 ? 52 PRO Q CD 1 +ATOM 30857 N N . ALA Q 1 53 ? 27.681 50.431 32.078 1.00 121.61 ? 53 ALA Q N 1 +ATOM 30858 C CA . ALA Q 1 53 ? 27.023 49.116 32.182 1.00 136.58 ? 53 ALA Q CA 1 +ATOM 30859 C C . ALA Q 1 53 ? 27.746 48.301 33.233 1.00 146.07 ? 53 ALA Q C 1 +ATOM 30860 O O . ALA Q 1 53 ? 28.909 48.572 33.554 1.00 149.42 ? 53 ALA Q O 1 +ATOM 30861 C CB . ALA Q 1 53 ? 26.996 48.374 30.841 1.00 111.16 ? 53 ALA Q CB 1 +ATOM 30862 N N . SER Q 1 54 ? 27.079 47.280 33.757 1.00 156.93 ? 54 SER Q N 1 +ATOM 30863 C CA . SER Q 1 54 ? 27.808 46.301 34.536 1.00 154.17 ? 54 SER Q CA 1 +ATOM 30864 C C . SER Q 1 54 ? 28.941 45.724 33.687 1.00 152.74 ? 54 SER Q C 1 +ATOM 30865 O O . SER Q 1 54 ? 28.799 45.476 32.464 1.00 236.23 ? 54 SER Q O 1 +ATOM 30866 C CB . SER Q 1 54 ? 26.901 45.178 35.033 1.00 180.63 ? 54 SER Q CB 1 +ATOM 30867 O OG . SER Q 1 54 ? 27.637 44.008 35.368 1.00 206.80 ? 54 SER Q OG 1 +ATOM 30868 N N . ASN Q 1 55 ? 30.070 45.497 34.348 1.00 97.00 ? 55 ASN Q N 1 +ATOM 30869 C CA . ASN Q 1 55 ? 31.219 44.860 33.726 1.00 74.17 ? 55 ASN Q CA 1 +ATOM 30870 C C . ASN Q 1 55 ? 30.853 43.575 33.000 1.00 78.76 ? 55 ASN Q C 1 +ATOM 30871 O O . ASN Q 1 55 ? 31.442 43.200 31.961 1.00 93.83 ? 55 ASN Q O 1 +ATOM 30872 C CB . ASN Q 1 55 ? 32.220 44.548 34.808 1.00 66.14 ? 55 ASN Q CB 1 +ATOM 30873 C CG . ASN Q 1 55 ? 33.581 44.294 34.257 1.00 94.75 ? 55 ASN Q CG 1 +ATOM 30874 O OD1 . ASN Q 1 55 ? 33.911 44.619 33.107 1.00 118.00 ? 55 ASN Q OD1 1 +ATOM 30875 N ND2 . ASN Q 1 55 ? 34.411 43.747 35.093 1.00 101.66 ? 55 ASN Q ND2 1 +ATOM 30876 N N . PHE Q 1 56 ? 29.792 42.937 33.500 1.00 92.95 ? 56 PHE Q N 1 +ATOM 30877 C CA . PHE Q 1 56 ? 29.384 41.605 33.064 1.00 91.04 ? 56 PHE Q CA 1 +ATOM 30878 C C . PHE Q 1 56 ? 28.247 41.615 32.047 1.00 103.70 ? 56 PHE Q C 1 +ATOM 30879 O O . PHE Q 1 56 ? 27.782 40.556 31.617 1.00 130.07 ? 56 PHE Q O 1 +ATOM 30880 C CB . PHE Q 1 56 ? 28.906 40.791 34.265 1.00 85.62 ? 56 PHE Q CB 1 +ATOM 30881 C CG . PHE Q 1 56 ? 29.921 40.693 35.377 1.00 74.95 ? 56 PHE Q CG 1 +ATOM 30882 C CD1 . PHE Q 1 56 ? 31.166 40.091 35.183 1.00 82.01 ? 56 PHE Q CD1 1 +ATOM 30883 C CD2 . PHE Q 1 56 ? 29.645 41.205 36.596 1.00 78.35 ? 56 PHE Q CD2 1 +ATOM 30884 C CE1 . PHE Q 1 56 ? 32.131 40.078 36.185 1.00 62.07 ? 56 PHE Q CE1 1 +ATOM 30885 C CE2 . PHE Q 1 56 ? 30.582 41.117 37.629 1.00 84.83 ? 56 PHE Q CE2 1 +ATOM 30886 C CZ . PHE Q 1 56 ? 31.836 40.569 37.419 1.00 54.60 ? 56 PHE Q CZ 1 +ATOM 30887 N N . SER Q 1 57 ? 27.744 42.785 31.691 1.00 109.58 ? 57 SER Q N 1 +ATOM 30888 C CA . SER Q 1 57 ? 26.680 42.849 30.693 1.00 106.37 ? 57 SER Q CA 1 +ATOM 30889 C C . SER Q 1 57 ? 27.253 42.593 29.293 1.00 99.62 ? 57 SER Q C 1 +ATOM 30890 O O . SER Q 1 57 ? 28.062 43.351 28.763 1.00 68.19 ? 57 SER Q O 1 +ATOM 30891 C CB . SER Q 1 57 ? 25.961 44.197 30.758 1.00 140.76 ? 57 SER Q CB 1 +ATOM 30892 O OG . SER Q 1 57 ? 25.145 44.265 31.913 1.00 175.58 ? 57 SER Q OG 1 +ATOM 30893 N N . THR Q 1 58 ? 26.815 41.510 28.679 1.00 100.77 ? 58 THR Q N 1 +ATOM 30894 C CA . THR Q 1 58 ? 27.287 41.166 27.351 1.00 104.27 ? 58 THR Q CA 1 +ATOM 30895 C C . THR Q 1 58 ? 26.737 42.130 26.342 1.00 110.88 ? 58 THR Q C 1 +ATOM 30896 O O . THR Q 1 58 ? 25.603 42.617 26.458 1.00 147.14 ? 58 THR Q O 1 +ATOM 30897 C CB . THR Q 1 58 ? 26.835 39.747 26.970 1.00 122.56 ? 58 THR Q CB 1 +ATOM 30898 O OG1 . THR Q 1 58 ? 25.398 39.657 26.971 1.00 153.86 ? 58 THR Q OG1 1 +ATOM 30899 C CG2 . THR Q 1 58 ? 27.368 38.772 27.961 1.00 149.66 ? 58 THR Q CG2 1 +ATOM 30900 N N . ALA Q 1 59 ? 27.435 42.289 25.243 1.00 126.55 ? 59 ALA Q N 1 +ATOM 30901 C CA . ALA Q 1 59 ? 26.904 43.189 24.233 1.00 173.08 ? 59 ALA Q CA 1 +ATOM 30902 C C . ALA Q 1 59 ? 25.751 42.572 23.411 1.00 175.62 ? 59 ALA Q C 1 +ATOM 30903 O O . ALA Q 1 59 ? 24.945 43.289 22.814 1.00 108.54 ? 59 ALA Q O 1 +ATOM 30904 C CB . ALA Q 1 59 ? 28.006 43.628 23.318 1.00 169.59 ? 59 ALA Q CB 1 +ATOM 30905 N N . VAL Q 1 60 ? 25.668 41.241 23.416 1.00 156.48 ? 60 VAL Q N 1 +ATOM 30906 C CA . VAL Q 1 60 ? 24.718 40.499 22.592 1.00 113.76 ? 60 VAL Q CA 1 +ATOM 30907 C C . VAL Q 1 60 ? 23.985 39.482 23.470 1.00 96.86 ? 60 VAL Q C 1 +ATOM 30908 O O . VAL Q 1 60 ? 24.607 38.839 24.314 1.00 155.69 ? 60 VAL Q O 1 +ATOM 30909 C CB . VAL Q 1 60 ? 25.481 39.776 21.469 1.00 104.53 ? 60 VAL Q CB 1 +ATOM 30910 C CG1 . VAL Q 1 60 ? 24.540 38.962 20.577 1.00 118.87 ? 60 VAL Q CG1 1 +ATOM 30911 C CG2 . VAL Q 1 60 ? 26.270 40.778 20.644 1.00 105.26 ? 60 VAL Q CG2 1 +ATOM 30912 N N . PRO Q 1 61 ? 22.665 39.313 23.274 1.00 103.02 ? 61 PRO Q N 1 +ATOM 30913 C CA . PRO Q 1 61 ? 21.955 38.287 24.040 1.00 123.89 ? 61 PRO Q CA 1 +ATOM 30914 C C . PRO Q 1 61 ? 22.432 36.860 23.770 1.00 137.06 ? 61 PRO Q C 1 +ATOM 30915 O O . PRO Q 1 61 ? 22.811 36.522 22.635 1.00 117.04 ? 61 PRO Q O 1 +ATOM 30916 C CB . PRO Q 1 61 ? 20.502 38.436 23.587 1.00 131.15 ? 61 PRO Q CB 1 +ATOM 30917 C CG . PRO Q 1 61 ? 20.584 39.080 22.252 1.00 135.49 ? 61 PRO Q CG 1 +ATOM 30918 C CD . PRO Q 1 61 ? 21.772 39.996 22.328 1.00 122.33 ? 61 PRO Q CD 1 +ATOM 30919 N N . GLN Q 1 62 ? 22.424 36.042 24.823 1.00 132.33 ? 62 GLN Q N 1 +ATOM 30920 C CA . GLN Q 1 62 ? 23.002 34.694 24.769 1.00 115.33 ? 62 GLN Q CA 1 +ATOM 30921 C C . GLN Q 1 62 ? 21.968 33.704 24.305 1.00 125.67 ? 62 GLN Q C 1 +ATOM 30922 O O . GLN Q 1 62 ? 21.943 32.572 24.759 1.00 67.43 ? 62 GLN Q O 1 +ATOM 30923 C CB . GLN Q 1 62 ? 23.513 34.279 26.148 1.00 104.32 ? 62 GLN Q CB 1 +ATOM 30924 C CG . GLN Q 1 62 ? 24.443 35.284 26.801 1.00 83.60 ? 62 GLN Q CG 1 +ATOM 30925 C CD . GLN Q 1 62 ? 25.637 35.533 25.916 1.00 72.47 ? 62 GLN Q CD 1 +ATOM 30926 O OE1 . GLN Q 1 62 ? 26.582 34.763 25.909 1.00 73.05 ? 62 GLN Q OE1 1 +ATOM 30927 N NE2 . GLN Q 1 62 ? 25.633 36.638 25.233 1.00 100.20 ? 62 GLN Q NE2 1 +ATOM 30928 N N . SER Q 1 63 ? 21.080 34.157 23.425 1.00 153.66 ? 63 SER Q N 1 +ATOM 30929 C CA . SER Q 1 63 ? 19.812 33.472 23.189 1.00 154.59 ? 63 SER Q CA 1 +ATOM 30930 C C . SER Q 1 63 ? 19.677 32.983 21.735 1.00 126.36 ? 63 SER Q C 1 +ATOM 30931 O O . SER Q 1 63 ? 18.598 32.565 21.308 1.00 141.15 ? 63 SER Q O 1 +ATOM 30932 C CB . SER Q 1 63 ? 18.643 34.399 23.595 1.00 134.27 ? 63 SER Q CB 1 +ATOM 30933 O OG . SER Q 1 63 ? 18.577 35.593 22.815 1.00 101.92 ? 63 SER Q OG 1 +ATOM 30934 N N . ALA Q 1 64 ? 20.772 33.084 20.984 1.00 77.35 ? 64 ALA Q N 1 +ATOM 30935 C CA . ALA Q 1 64 ? 20.761 32.860 19.557 1.00 69.31 ? 64 ALA Q CA 1 +ATOM 30936 C C . ALA Q 1 64 ? 20.225 31.471 19.189 1.00 92.30 ? 64 ALA Q C 1 +ATOM 30937 O O . ALA Q 1 64 ? 19.479 31.316 18.199 1.00 116.40 ? 64 ALA Q O 1 +ATOM 30938 C CB . ALA Q 1 64 ? 22.163 33.054 19.024 1.00 56.14 ? 64 ALA Q CB 1 +ATOM 30939 N N . THR Q 1 65 ? 20.565 30.482 20.013 1.00 97.42 ? 65 THR Q N 1 +ATOM 30940 C CA . THR Q 1 65 ? 20.146 29.105 19.810 1.00 100.59 ? 65 THR Q CA 1 +ATOM 30941 C C . THR Q 1 65 ? 18.641 28.968 19.665 1.00 106.41 ? 65 THR Q C 1 +ATOM 30942 O O . THR Q 1 65 ? 18.141 28.362 18.698 1.00 143.78 ? 65 THR Q O 1 +ATOM 30943 C CB . THR Q 1 65 ? 20.528 28.276 21.016 1.00 123.82 ? 65 THR Q CB 1 +ATOM 30944 O OG1 . THR Q 1 65 ? 21.814 28.698 21.463 1.00 154.38 ? 65 THR Q OG1 1 +ATOM 30945 C CG2 . THR Q 1 65 ? 20.545 26.788 20.659 1.00 173.21 ? 65 THR Q CG2 1 +ATOM 30946 N N . ALA Q 1 66 ? 17.904 29.579 20.591 1.00 106.30 ? 66 ALA Q N 1 +ATOM 30947 C CA . ALA Q 1 66 ? 16.436 29.485 20.578 1.00 115.18 ? 66 ALA Q CA 1 +ATOM 30948 C C . ALA Q 1 66 ? 15.790 30.282 19.425 1.00 102.26 ? 66 ALA Q C 1 +ATOM 30949 O O . ALA Q 1 66 ? 14.827 29.829 18.802 1.00 67.05 ? 66 ALA Q O 1 +ATOM 30950 C CB . ALA Q 1 66 ? 15.884 29.956 21.894 1.00 117.73 ? 66 ALA Q CB 1 +ATOM 30951 N N . MET Q 1 67 ? 16.426 31.392 19.062 1.00 92.12 ? 67 MET Q N 1 +ATOM 30952 C CA . MET Q 1 67 ? 16.017 32.142 17.885 1.00 84.79 ? 67 MET Q CA 1 +ATOM 30953 C C . MET Q 1 67 ? 16.140 31.303 16.599 1.00 49.89 ? 67 MET Q C 1 +ATOM 30954 O O . MET Q 1 67 ? 15.284 31.374 15.727 1.00 43.47 ? 67 MET Q O 1 +ATOM 30955 C CB . MET Q 1 67 ? 16.848 33.449 17.756 1.00 108.90 ? 67 MET Q CB 1 +ATOM 30956 C CG . MET Q 1 67 ? 16.586 34.508 18.834 1.00 107.80 ? 67 MET Q CG 1 +ATOM 30957 S SD . MET Q 1 67 ? 17.834 35.848 18.769 1.00 57.90 ? 67 MET Q SD 1 +ATOM 30958 C CE . MET Q 1 67 ? 17.175 36.970 20.002 1.00 87.51 ? 67 MET Q CE 1 +ATOM 30959 N N . LEU Q 1 68 ? 17.276 30.645 16.435 1.00 36.53 ? 68 LEU Q N 1 +ATOM 30960 C CA . LEU Q 1 68 ? 17.499 29.850 15.261 1.00 40.58 ? 68 LEU Q CA 1 +ATOM 30961 C C . LEU Q 1 68 ? 16.502 28.730 15.174 1.00 46.72 ? 68 LEU Q C 1 +ATOM 30962 O O . LEU Q 1 68 ? 15.968 28.465 14.119 1.00 76.09 ? 68 LEU Q O 1 +ATOM 30963 C CB . LEU Q 1 68 ? 18.886 29.226 15.262 1.00 61.66 ? 68 LEU Q CB 1 +ATOM 30964 C CG . LEU Q 1 68 ? 19.098 28.138 14.160 1.00 60.08 ? 68 LEU Q CG 1 +ATOM 30965 C CD1 . LEU Q 1 68 ? 19.059 28.812 12.801 1.00 73.06 ? 68 LEU Q CD1 1 +ATOM 30966 C CD2 . LEU Q 1 68 ? 20.410 27.384 14.320 1.00 60.97 ? 68 LEU Q CD2 1 +ATOM 30967 N N . VAL Q 1 69 ? 16.254 28.035 16.278 1.00 66.45 ? 69 VAL Q N 1 +ATOM 30968 C CA . VAL Q 1 69 ? 15.265 26.938 16.302 1.00 67.14 ? 69 VAL Q CA 1 +ATOM 30969 C C . VAL Q 1 69 ? 13.889 27.474 15.895 1.00 94.50 ? 69 VAL Q C 1 +ATOM 30970 O O . VAL Q 1 69 ? 13.189 26.869 15.080 1.00 89.51 ? 69 VAL Q O 1 +ATOM 30971 C CB . VAL Q 1 69 ? 15.133 26.256 17.694 1.00 59.30 ? 69 VAL Q CB 1 +ATOM 30972 C CG1 . VAL Q 1 69 ? 13.989 25.278 17.681 1.00 53.42 ? 69 VAL Q CG1 1 +ATOM 30973 C CG2 . VAL Q 1 69 ? 16.423 25.532 18.099 1.00 66.34 ? 69 VAL Q CG2 1 +ATOM 30974 N N . THR Q 1 70 ? 13.539 28.645 16.425 1.00 122.63 ? 70 THR Q N 1 +ATOM 30975 C CA . THR Q 1 70 ? 12.261 29.284 16.111 1.00 127.34 ? 70 THR Q CA 1 +ATOM 30976 C C . THR Q 1 70 ? 12.158 29.681 14.641 1.00 97.62 ? 70 THR Q C 1 +ATOM 30977 O O . THR Q 1 70 ? 11.169 29.393 13.973 1.00 116.31 ? 70 THR Q O 1 +ATOM 30978 C CB . THR Q 1 70 ? 12.047 30.523 16.986 1.00 125.45 ? 70 THR Q CB 1 +ATOM 30979 O OG1 . THR Q 1 70 ? 12.159 30.130 18.365 1.00 177.36 ? 70 THR Q OG1 1 +ATOM 30980 C CG2 . THR Q 1 70 ? 10.658 31.140 16.716 1.00 105.94 ? 70 THR Q CG2 1 +ATOM 30981 N N . ALA Q 1 71 ? 13.238 30.234 14.117 1.00 72.76 ? 71 ALA Q N 1 +ATOM 30982 C CA . ALA Q 1 71 ? 13.289 30.563 12.702 1.00 71.52 ? 71 ALA Q CA 1 +ATOM 30983 C C . ALA Q 1 71 ? 13.138 29.313 11.840 1.00 61.70 ? 71 ALA Q C 1 +ATOM 30984 O O . ALA Q 1 71 ? 12.468 29.327 10.799 1.00 75.57 ? 71 ALA Q O 1 +ATOM 30985 C CB . ALA Q 1 71 ? 14.586 31.324 12.368 1.00 71.19 ? 71 ALA Q CB 1 +ATOM 30986 N N . LEU Q 1 72 ? 13.834 28.260 12.222 1.00 63.66 ? 72 LEU Q N 1 +ATOM 30987 C CA . LEU Q 1 72 ? 13.792 27.003 11.467 1.00 84.66 ? 72 LEU Q CA 1 +ATOM 30988 C C . LEU Q 1 72 ? 12.376 26.468 11.440 1.00 88.84 ? 72 LEU Q C 1 +ATOM 30989 O O . LEU Q 1 72 ? 12.017 25.707 10.548 1.00 84.28 ? 72 LEU Q O 1 +ATOM 30990 C CB . LEU Q 1 72 ? 14.746 25.951 12.076 1.00 91.33 ? 72 LEU Q CB 1 +ATOM 30991 C CG . LEU Q 1 72 ? 16.240 26.254 11.908 1.00 92.12 ? 72 LEU Q CG 1 +ATOM 30992 C CD1 . LEU Q 1 72 ? 17.027 25.422 12.896 1.00 91.30 ? 72 LEU Q CD1 1 +ATOM 30993 C CD2 . LEU Q 1 72 ? 16.720 26.012 10.489 1.00 76.59 ? 72 LEU Q CD2 1 +ATOM 30994 N N . LYS Q 1 73 ? 11.590 26.806 12.460 1.00 89.84 ? 73 LYS Q N 1 +ATOM 30995 C CA . LYS Q 1 73 ? 10.217 26.298 12.537 1.00 93.75 ? 73 LYS Q CA 1 +ATOM 30996 C C . LYS Q 1 73 ? 9.299 27.170 11.703 1.00 102.52 ? 73 LYS Q C 1 +ATOM 30997 O O . LYS Q 1 73 ? 8.445 26.651 11.001 1.00 130.19 ? 73 LYS Q O 1 +ATOM 30998 C CB . LYS Q 1 73 ? 9.715 26.220 13.986 1.00 80.50 ? 73 LYS Q CB 1 +ATOM 30999 C CG . LYS Q 1 73 ? 8.407 25.435 14.164 1.00 60.53 ? 73 LYS Q CG 1 +ATOM 31000 C CD . LYS Q 1 73 ? 7.962 25.415 15.636 1.00 59.63 ? 73 LYS Q CD 1 +ATOM 31001 C CE . LYS Q 1 73 ? 6.457 25.305 15.785 1.00 62.48 ? 73 LYS Q CE 1 +ATOM 31002 N NZ . LYS Q 1 73 ? 6.018 24.029 16.402 1.00 57.18 ? 73 LYS Q NZ 1 +ATOM 31003 N N . ASP Q 1 74 ? 9.451 28.483 11.830 1.00 97.20 ? 74 ASP Q N 1 +ATOM 31004 C CA . ASP Q 1 74 ? 8.550 29.410 11.185 1.00 110.71 ? 74 ASP Q CA 1 +ATOM 31005 C C . ASP Q 1 74 ? 8.611 29.231 9.678 1.00 105.61 ? 74 ASP Q C 1 +ATOM 31006 O O . ASP Q 1 74 ? 7.641 29.538 8.974 1.00 116.48 ? 74 ASP Q O 1 +ATOM 31007 C CB . ASP Q 1 74 ? 8.893 30.864 11.588 1.00 104.22 ? 74 ASP Q CB 1 +ATOM 31008 C CG . ASP Q 1 74 ? 8.567 31.169 13.060 1.00 95.72 ? 74 ASP Q CG 1 +ATOM 31009 O OD1 . ASP Q 1 74 ? 7.600 30.578 13.627 1.00 119.62 ? 74 ASP Q OD1 1 +ATOM 31010 O OD2 . ASP Q 1 74 ? 9.208 32.077 13.621 1.00 86.51 ? 74 ASP Q OD2 1 +ATOM 31011 N N . SER Q 1 75 ? 9.776 28.819 9.185 1.00 91.68 ? 75 SER Q N 1 +ATOM 31012 C CA . SER Q 1 75 ? 10.010 28.688 7.735 1.00 98.87 ? 75 SER Q CA 1 +ATOM 31013 C C . SER Q 1 75 ? 9.092 27.658 7.083 1.00 88.45 ? 75 SER Q C 1 +ATOM 31014 O O . SER Q 1 75 ? 8.856 27.702 5.881 1.00 61.21 ? 75 SER Q O 1 +ATOM 31015 C CB . SER Q 1 75 ? 11.474 28.316 7.451 1.00 95.68 ? 75 SER Q CB 1 +ATOM 31016 O OG . SER Q 1 75 ? 11.678 26.922 7.534 1.00 79.87 ? 75 SER Q OG 1 +ATOM 31017 N N . ARG Q 1 76 ? 8.622 26.710 7.892 1.00 103.61 ? 76 ARG Q N 1 +ATOM 31018 C CA . ARG Q 1 76 ? 7.818 25.572 7.431 1.00 101.93 ? 76 ARG Q CA 1 +ATOM 31019 C C . ARG Q 1 76 ? 8.573 24.740 6.418 1.00 69.31 ? 76 ARG Q C 1 +ATOM 31020 O O . ARG Q 1 76 ? 8.002 24.178 5.493 1.00 61.20 ? 76 ARG Q O 1 +ATOM 31021 C CB . ARG Q 1 76 ? 6.510 26.052 6.831 1.00 138.67 ? 76 ARG Q CB 1 +ATOM 31022 C CG . ARG Q 1 76 ? 5.626 26.824 7.796 1.00 159.74 ? 76 ARG Q CG 1 +ATOM 31023 C CD . ARG Q 1 76 ? 4.328 27.224 7.103 1.00 167.40 ? 76 ARG Q CD 1 +ATOM 31024 N NE . ARG Q 1 76 ? 4.565 28.245 6.080 1.00 182.86 ? 76 ARG Q NE 1 +ATOM 31025 C CZ . ARG Q 1 76 ? 4.766 28.005 4.786 1.00 166.96 ? 76 ARG Q CZ 1 +ATOM 31026 N NH1 . ARG Q 1 76 ? 4.762 26.762 4.306 1.00 142.72 ? 76 ARG Q NH1 1 +ATOM 31027 N NH2 . ARG Q 1 76 ? 4.987 29.026 3.968 1.00 160.68 ? 76 ARG Q NH2 1 +ATOM 31028 N N . TRP Q 1 77 ? 9.868 24.641 6.637 1.00 74.25 ? 77 TRP Q N 1 +ATOM 31029 C CA . TRP Q 1 77 ? 10.704 23.665 5.957 1.00 118.77 ? 77 TRP Q CA 1 +ATOM 31030 C C . TRP Q 1 77 ? 11.210 22.540 6.913 1.00 119.35 ? 77 TRP Q C 1 +ATOM 31031 O O . TRP Q 1 77 ? 11.436 21.400 6.497 1.00 91.04 ? 77 TRP Q O 1 +ATOM 31032 C CB . TRP Q 1 77 ? 11.887 24.406 5.333 1.00 125.23 ? 77 TRP Q CB 1 +ATOM 31033 C CG . TRP Q 1 77 ? 11.636 24.860 3.962 1.00 114.85 ? 77 TRP Q CG 1 +ATOM 31034 C CD1 . TRP Q 1 77 ? 10.878 25.909 3.582 1.00 124.77 ? 77 TRP Q CD1 1 +ATOM 31035 C CD2 . TRP Q 1 77 ? 12.162 24.281 2.768 1.00 113.52 ? 77 TRP Q CD2 1 +ATOM 31036 N NE1 . TRP Q 1 77 ? 10.887 26.021 2.221 1.00 155.86 ? 77 TRP Q NE1 1 +ATOM 31037 C CE2 . TRP Q 1 77 ? 11.677 25.033 1.697 1.00 127.53 ? 77 TRP Q CE2 1 +ATOM 31038 C CE3 . TRP Q 1 77 ? 13.023 23.215 2.503 1.00 143.98 ? 77 TRP Q CE3 1 +ATOM 31039 C CZ2 . TRP Q 1 77 ? 12.021 24.760 0.368 1.00 142.00 ? 77 TRP Q CZ2 1 +ATOM 31040 C CZ3 . TRP Q 1 77 ? 13.344 22.930 1.183 1.00 170.00 ? 77 TRP Q CZ3 1 +ATOM 31041 C CH2 . TRP Q 1 77 ? 12.850 23.708 0.133 1.00 152.95 ? 77 TRP Q CH2 1 +ATOM 31042 N N . PHE Q 1 78 ? 11.438 22.902 8.174 1.00 115.65 ? 78 PHE Q N 1 +ATOM 31043 C CA . PHE Q 1 78 ? 12.094 22.042 9.147 1.00 96.68 ? 78 PHE Q CA 1 +ATOM 31044 C C . PHE Q 1 78 ? 11.191 21.782 10.355 1.00 104.20 ? 78 PHE Q C 1 +ATOM 31045 O O . PHE Q 1 78 ? 10.509 22.694 10.850 1.00 83.07 ? 78 PHE Q O 1 +ATOM 31046 C CB . PHE Q 1 78 ? 13.384 22.711 9.655 1.00 117.00 ? 78 PHE Q CB 1 +ATOM 31047 C CG . PHE Q 1 78 ? 14.362 23.083 8.569 1.00 112.44 ? 78 PHE Q CG 1 +ATOM 31048 C CD1 . PHE Q 1 78 ? 15.166 22.117 7.961 1.00 92.77 ? 78 PHE Q CD1 1 +ATOM 31049 C CD2 . PHE Q 1 78 ? 14.540 24.415 8.229 1.00 101.32 ? 78 PHE Q CD2 1 +ATOM 31050 C CE1 . PHE Q 1 78 ? 16.077 22.467 6.990 1.00 73.39 ? 78 PHE Q CE1 1 +ATOM 31051 C CE2 . PHE Q 1 78 ? 15.460 24.767 7.267 1.00 92.78 ? 78 PHE Q CE2 1 +ATOM 31052 C CZ . PHE Q 1 78 ? 16.212 23.786 6.630 1.00 72.80 ? 78 PHE Q CZ 1 +ATOM 31053 N N . ILE Q 1 79 ? 11.298 20.565 10.888 1.00 123.16 ? 79 ILE Q N 1 +ATOM 31054 C CA . ILE Q 1 79 ? 10.823 20.213 12.239 1.00 112.63 ? 79 ILE Q CA 1 +ATOM 31055 C C . ILE Q 1 79 ? 12.009 20.185 13.186 1.00 79.21 ? 79 ILE Q C 1 +ATOM 31056 O O . ILE Q 1 79 ? 13.047 19.581 12.844 1.00 76.98 ? 79 ILE Q O 1 +ATOM 31057 C CB . ILE Q 1 79 ? 10.239 18.800 12.269 1.00 126.24 ? 79 ILE Q CB 1 +ATOM 31058 C CG1 . ILE Q 1 79 ? 9.247 18.589 11.128 1.00 149.09 ? 79 ILE Q CG1 1 +ATOM 31059 C CG2 . ILE Q 1 79 ? 9.570 18.541 13.602 1.00 142.88 ? 79 ILE Q CG2 1 +ATOM 31060 C CD1 . ILE Q 1 79 ? 9.054 17.130 10.750 1.00 128.06 ? 79 ILE Q CD1 1 +ATOM 31061 N N . PRO Q 1 80 ? 11.951 21.016 14.228 1.00 74.58 ? 80 PRO Q N 1 +ATOM 31062 C CA . PRO Q 1 80 ? 13.133 21.009 15.022 1.00 91.72 ? 80 PRO Q CA 1 +ATOM 31063 C C . PRO Q 1 80 ? 12.931 19.964 16.051 1.00 67.67 ? 80 PRO Q C 1 +ATOM 31064 O O . PRO Q 1 80 ? 11.906 19.953 16.712 1.00 61.12 ? 80 PRO Q O 1 +ATOM 31065 C CB . PRO Q 1 80 ? 13.186 22.440 15.611 1.00 110.51 ? 80 PRO Q CB 1 +ATOM 31066 C CG . PRO Q 1 80 ? 12.460 23.268 14.622 1.00 98.96 ? 80 PRO Q CG 1 +ATOM 31067 C CD . PRO Q 1 80 ? 11.327 22.353 14.231 1.00 96.97 ? 80 PRO Q CD 1 +ATOM 31068 N N . LEU Q 1 81 ? 13.988 19.223 16.300 1.00 56.81 ? 81 LEU Q N 1 +ATOM 31069 C CA . LEU Q 1 81 ? 14.027 18.377 17.416 1.00 76.65 ? 81 LEU Q CA 1 +ATOM 31070 C C . LEU Q 1 81 ? 14.699 19.097 18.588 1.00 80.51 ? 81 LEU Q C 1 +ATOM 31071 O O . LEU Q 1 81 ? 15.710 19.798 18.423 1.00 51.40 ? 81 LEU Q O 1 +ATOM 31072 C CB . LEU Q 1 81 ? 14.731 17.083 17.027 1.00 111.57 ? 81 LEU Q CB 1 +ATOM 31073 C CG . LEU Q 1 81 ? 14.076 16.474 15.781 1.00 115.84 ? 81 LEU Q CG 1 +ATOM 31074 C CD1 . LEU Q 1 81 ? 14.909 15.287 15.353 1.00 132.03 ? 81 LEU Q CD1 1 +ATOM 31075 C CD2 . LEU Q 1 81 ? 12.646 16.057 16.067 1.00 88.79 ? 81 LEU Q CD2 1 +ATOM 31076 N N . GLU Q 1 82 ? 14.123 18.864 19.778 1.00 98.23 ? 82 GLU Q N 1 +ATOM 31077 C CA . GLU Q 1 82 ? 14.608 19.450 21.014 1.00 85.89 ? 82 GLU Q CA 1 +ATOM 31078 C C . GLU Q 1 82 ? 15.907 18.742 21.496 1.00 120.80 ? 82 GLU Q C 1 +ATOM 31079 O O . GLU Q 1 82 ? 15.880 17.620 22.064 1.00 140.26 ? 82 GLU Q O 1 +ATOM 31080 C CB . GLU Q 1 82 ? 13.517 19.460 22.101 1.00 54.72 ? 82 GLU Q CB 1 +ATOM 31081 C CG . GLU Q 1 82 ? 13.950 20.101 23.413 1.00 63.24 ? 82 GLU Q CG 1 +ATOM 31082 C CD . GLU Q 1 82 ? 14.145 21.637 23.352 1.00 64.72 ? 82 GLU Q CD 1 +ATOM 31083 O OE1 . GLU Q 1 82 ? 14.878 22.167 22.482 1.00 58.81 ? 82 GLU Q OE1 1 +ATOM 31084 O OE2 . GLU Q 1 82 ? 13.716 22.314 24.314 1.00 67.11 ? 82 GLU Q OE2 1 +ATOM 31085 N N . ARG Q 1 83 ? 17.027 19.462 21.350 1.00 96.84 ? 83 ARG Q N 1 +ATOM 31086 C CA . ARG Q 1 83 ? 18.292 19.080 21.961 1.00 95.22 ? 83 ARG Q CA 1 +ATOM 31087 C C . ARG Q 1 83 ? 18.860 20.107 22.994 1.00 108.46 ? 83 ARG Q C 1 +ATOM 31088 O O . ARG Q 1 83 ? 19.729 19.754 23.796 1.00 83.67 ? 83 ARG Q O 1 +ATOM 31089 C CB . ARG Q 1 83 ? 19.290 18.809 20.842 1.00 81.76 ? 83 ARG Q CB 1 +ATOM 31090 C CG . ARG Q 1 83 ? 18.791 17.810 19.838 1.00 76.05 ? 83 ARG Q CG 1 +ATOM 31091 C CD . ARG Q 1 83 ? 18.717 16.413 20.420 1.00 97.17 ? 83 ARG Q CD 1 +ATOM 31092 N NE . ARG Q 1 83 ? 18.466 15.487 19.323 1.00 115.06 ? 83 ARG Q NE 1 +ATOM 31093 C CZ . ARG Q 1 83 ? 17.293 14.920 19.028 1.00 105.00 ? 83 ARG Q CZ 1 +ATOM 31094 N NH1 . ARG Q 1 83 ? 16.239 15.069 19.828 1.00 79.23 ? 83 ARG Q NH1 1 +ATOM 31095 N NH2 . ARG Q 1 83 ? 17.213 14.147 17.936 1.00 103.94 ? 83 ARG Q NH2 1 +ATOM 31096 N N . GLN Q 1 84 ? 18.396 21.365 22.978 1.00 111.28 ? 84 GLN Q N 1 +ATOM 31097 C CA . GLN Q 1 84 ? 18.948 22.367 23.908 1.00 103.30 ? 84 GLN Q CA 1 +ATOM 31098 C C . GLN Q 1 84 ? 18.666 21.949 25.332 1.00 77.60 ? 84 GLN Q C 1 +ATOM 31099 O O . GLN Q 1 84 ? 19.544 21.976 26.170 1.00 109.46 ? 84 GLN Q O 1 +ATOM 31100 C CB . GLN Q 1 84 ? 18.424 23.780 23.662 1.00 115.29 ? 84 GLN Q CB 1 +ATOM 31101 C CG . GLN Q 1 84 ? 19.421 24.896 24.038 1.00 115.82 ? 84 GLN Q CG 1 +ATOM 31102 C CD . GLN Q 1 84 ? 18.833 26.290 23.868 1.00 161.25 ? 84 GLN Q CD 1 +ATOM 31103 O OE1 . GLN Q 1 84 ? 18.020 26.533 22.963 1.00 259.80 ? 84 GLN Q OE1 1 +ATOM 31104 N NE2 . GLN Q 1 84 ? 19.198 27.200 24.754 1.00 146.18 ? 84 GLN Q NE2 1 +ATOM 31105 N N . GLY Q 1 85 ? 17.516 21.369 25.574 1.00 77.78 ? 85 GLY Q N 1 +ATOM 31106 C CA . GLY Q 1 85 ? 17.257 20.824 26.914 1.00 105.85 ? 85 GLY Q CA 1 +ATOM 31107 C C . GLY Q 1 85 ? 17.186 19.307 26.958 1.00 114.26 ? 85 GLY Q C 1 +ATOM 31108 O O . GLY Q 1 85 ? 16.364 18.751 27.702 1.00 125.54 ? 85 GLY Q O 1 +ATOM 31109 N N . LEU Q 1 86 ? 18.075 18.627 26.220 1.00 91.23 ? 86 LEU Q N 1 +ATOM 31110 C CA . LEU Q 1 86 ? 17.960 17.171 26.028 1.00 74.11 ? 86 LEU Q CA 1 +ATOM 31111 C C . LEU Q 1 86 ? 17.983 16.385 27.356 1.00 82.69 ? 86 LEU Q C 1 +ATOM 31112 O O . LEU Q 1 86 ? 17.275 15.384 27.521 1.00 74.57 ? 86 LEU Q O 1 +ATOM 31113 C CB . LEU Q 1 86 ? 19.078 16.647 25.147 1.00 76.82 ? 86 LEU Q CB 1 +ATOM 31114 C CG . LEU Q 1 86 ? 19.249 15.126 24.939 1.00 95.98 ? 86 LEU Q CG 1 +ATOM 31115 C CD1 . LEU Q 1 86 ? 18.017 14.486 24.311 1.00 106.39 ? 86 LEU Q CD1 1 +ATOM 31116 C CD2 . LEU Q 1 86 ? 20.469 14.847 24.065 1.00 107.79 ? 86 LEU Q CD2 1 +ATOM 31117 N N . GLN Q 1 87 ? 18.745 16.874 28.329 1.00 90.74 ? 87 GLN Q N 1 +ATOM 31118 C CA . GLN Q 1 87 ? 18.904 16.151 29.593 1.00 94.94 ? 87 GLN Q CA 1 +ATOM 31119 C C . GLN Q 1 87 ? 17.561 15.974 30.359 1.00 63.34 ? 87 GLN Q C 1 +ATOM 31120 O O . GLN Q 1 87 ? 17.223 14.905 30.860 1.00 65.92 ? 87 GLN Q O 1 +ATOM 31121 C CB . GLN Q 1 87 ? 19.972 16.859 30.451 1.00 120.91 ? 87 GLN Q CB 1 +ATOM 31122 C CG . GLN Q 1 87 ? 20.813 15.906 31.292 1.00 135.16 ? 87 GLN Q CG 1 +ATOM 31123 C CD . GLN Q 1 87 ? 21.238 14.648 30.535 1.00 145.84 ? 87 GLN Q CD 1 +ATOM 31124 O OE1 . GLN Q 1 87 ? 21.891 14.719 29.493 1.00 136.84 ? 87 GLN Q OE1 1 +ATOM 31125 N NE2 . GLN Q 1 87 ? 20.876 13.481 31.073 1.00 162.49 ? 87 GLN Q NE2 1 +ATOM 31126 N N . ASN Q 1 88 ? 16.817 17.047 30.455 1.00 52.38 ? 88 ASN Q N 1 +ATOM 31127 C CA . ASN Q 1 88 ? 15.528 17.012 31.073 1.00 63.13 ? 88 ASN Q CA 1 +ATOM 31128 C C . ASN Q 1 88 ? 14.579 16.066 30.342 1.00 76.07 ? 88 ASN Q C 1 +ATOM 31129 O O . ASN Q 1 88 ? 13.661 15.484 30.944 1.00 86.61 ? 88 ASN Q O 1 +ATOM 31130 C CB . ASN Q 1 88 ? 14.917 18.424 31.033 1.00 97.27 ? 88 ASN Q CB 1 +ATOM 31131 C CG . ASN Q 1 88 ? 15.784 19.431 31.722 1.00 75.67 ? 88 ASN Q CG 1 +ATOM 31132 O OD1 . ASN Q 1 88 ? 16.398 19.097 32.722 1.00 40.77 ? 88 ASN Q OD1 1 +ATOM 31133 N ND2 . ASN Q 1 88 ? 15.896 20.648 31.144 1.00 78.96 ? 88 ASN Q ND2 1 +ATOM 31134 N N . LEU Q 1 89 ? 14.665 16.075 29.012 1.00 78.61 ? 89 LEU Q N 1 +ATOM 31135 C CA . LEU Q 1 89 ? 13.782 15.286 28.178 1.00 67.96 ? 89 LEU Q CA 1 +ATOM 31136 C C . LEU Q 1 89 ? 14.006 13.800 28.565 1.00 78.85 ? 89 LEU Q C 1 +ATOM 31137 O O . LEU Q 1 89 ? 13.054 13.023 28.741 1.00 68.77 ? 89 LEU Q O 1 +ATOM 31138 C CB . LEU Q 1 89 ? 14.095 15.574 26.693 1.00 53.82 ? 89 LEU Q CB 1 +ATOM 31139 C CG . LEU Q 1 89 ? 13.022 15.431 25.636 1.00 48.55 ? 89 LEU Q CG 1 +ATOM 31140 C CD1 . LEU Q 1 89 ? 13.351 14.297 24.705 1.00 58.59 ? 89 LEU Q CD1 1 +ATOM 31141 C CD2 . LEU Q 1 89 ? 11.655 15.155 26.262 1.00 51.17 ? 89 LEU Q CD2 1 +ATOM 31142 N N . LEU Q 1 90 ? 15.272 13.440 28.732 1.00 86.11 ? 90 LEU Q N 1 +ATOM 31143 C CA . LEU Q 1 90 ? 15.640 12.060 29.035 1.00 92.32 ? 90 LEU Q CA 1 +ATOM 31144 C C . LEU Q 1 90 ? 15.206 11.695 30.451 1.00 93.37 ? 90 LEU Q C 1 +ATOM 31145 O O . LEU Q 1 90 ? 14.873 10.539 30.748 1.00 112.91 ? 90 LEU Q O 1 +ATOM 31146 C CB . LEU Q 1 90 ? 17.149 11.871 28.886 1.00 81.09 ? 90 LEU Q CB 1 +ATOM 31147 C CG . LEU Q 1 90 ? 17.656 12.140 27.494 1.00 85.58 ? 90 LEU Q CG 1 +ATOM 31148 C CD1 . LEU Q 1 90 ? 19.155 12.379 27.544 1.00 82.89 ? 90 LEU Q CD1 1 +ATOM 31149 C CD2 . LEU Q 1 90 ? 17.292 10.966 26.587 1.00 114.75 ? 90 LEU Q CD2 1 +ATOM 31150 N N . ASN Q 1 91 ? 15.207 12.693 31.319 1.00 80.91 ? 91 ASN Q N 1 +ATOM 31151 C CA . ASN Q 1 91 ? 14.771 12.486 32.666 1.00 77.88 ? 91 ASN Q CA 1 +ATOM 31152 C C . ASN Q 1 91 ? 13.275 12.217 32.754 1.00 116.62 ? 91 ASN Q C 1 +ATOM 31153 O O . ASN Q 1 91 ? 12.847 11.296 33.453 1.00 141.94 ? 91 ASN Q O 1 +ATOM 31154 C CB . ASN Q 1 91 ? 15.136 13.669 33.523 1.00 79.57 ? 91 ASN Q CB 1 +ATOM 31155 C CG . ASN Q 1 91 ? 15.858 13.203 34.748 1.00 75.88 ? 91 ASN Q CG 1 +ATOM 31156 O OD1 . ASN Q 1 91 ? 16.875 12.535 34.611 1.00 60.87 ? 91 ASN Q OD1 1 +ATOM 31157 N ND2 . ASN Q 1 91 ? 15.303 13.453 35.952 1.00 99.77 ? 91 ASN Q ND2 1 +ATOM 31158 N N . GLU Q 1 92 ? 12.477 13.054 32.096 1.00 112.02 ? 92 GLU Q N 1 +ATOM 31159 C CA . GLU Q 1 92 ? 11.043 12.844 32.095 1.00 99.94 ? 92 GLU Q CA 1 +ATOM 31160 C C . GLU Q 1 92 ? 10.748 11.442 31.579 1.00 78.15 ? 92 GLU Q C 1 +ATOM 31161 O O . GLU Q 1 92 ? 9.764 10.794 31.984 1.00 74.34 ? 92 GLU Q O 1 +ATOM 31162 C CB . GLU Q 1 92 ? 10.319 13.918 31.262 1.00 110.16 ? 92 GLU Q CB 1 +ATOM 31163 C CG . GLU Q 1 92 ? 9.838 15.114 32.064 1.00 96.27 ? 92 GLU Q CG 1 +ATOM 31164 C CD . GLU Q 1 92 ? 8.979 14.725 33.279 1.00 102.26 ? 92 GLU Q CD 1 +ATOM 31165 O OE1 . GLU Q 1 92 ? 7.903 14.064 33.135 1.00 72.43 ? 92 GLU Q OE1 1 +ATOM 31166 O OE2 . GLU Q 1 92 ? 9.357 15.145 34.398 1.00 89.26 ? 92 GLU Q OE2 1 +ATOM 31167 N N . ARG Q 1 93 ? 11.503 11.037 30.572 1.00 63.34 ? 93 ARG Q N 1 +ATOM 31168 C CA . ARG Q 1 93 ? 11.284 9.732 29.997 1.00 91.83 ? 93 ARG Q CA 1 +ATOM 31169 C C . ARG Q 1 93 ? 11.643 8.626 31.018 1.00 114.38 ? 93 ARG Q C 1 +ATOM 31170 O O . ARG Q 1 93 ? 11.028 7.556 31.035 1.00 138.79 ? 93 ARG Q O 1 +ATOM 31171 C CB . ARG Q 1 93 ? 12.037 9.629 28.663 1.00 84.50 ? 93 ARG Q CB 1 +ATOM 31172 C CG . ARG Q 1 93 ? 11.414 10.507 27.594 1.00 67.36 ? 93 ARG Q CG 1 +ATOM 31173 C CD . ARG Q 1 93 ? 12.311 10.715 26.385 1.00 86.64 ? 93 ARG Q CD 1 +ATOM 31174 N NE . ARG Q 1 93 ? 11.929 9.873 25.255 1.00 97.86 ? 93 ARG Q NE 1 +ATOM 31175 C CZ . ARG Q 1 93 ? 12.514 8.727 24.924 1.00 109.87 ? 93 ARG Q CZ 1 +ATOM 31176 N NH1 . ARG Q 1 93 ? 13.517 8.227 25.639 1.00 126.66 ? 93 ARG Q NH1 1 +ATOM 31177 N NH2 . ARG Q 1 93 ? 12.094 8.087 23.846 1.00 123.29 ? 93 ARG Q NH2 1 +ATOM 31178 N N . LYS Q 1 94 ? 12.635 8.875 31.868 1.00 116.38 ? 94 LYS Q N 1 +ATOM 31179 C CA . LYS Q 1 94 ? 12.972 7.917 32.924 1.00 106.14 ? 94 LYS Q CA 1 +ATOM 31180 C C . LYS Q 1 94 ? 11.802 7.822 33.876 1.00 94.71 ? 94 LYS Q C 1 +ATOM 31181 O O . LYS Q 1 94 ? 11.466 6.712 34.347 1.00 84.11 ? 94 LYS Q O 1 +ATOM 31182 C CB . LYS Q 1 94 ? 14.200 8.367 33.701 1.00 132.45 ? 94 LYS Q CB 1 +ATOM 31183 C CG . LYS Q 1 94 ? 15.539 7.893 33.152 1.00 144.47 ? 94 LYS Q CG 1 +ATOM 31184 C CD . LYS Q 1 94 ? 16.677 8.575 33.906 1.00 149.68 ? 94 LYS Q CD 1 +ATOM 31185 C CE . LYS Q 1 94 ? 18.005 7.840 33.786 1.00 128.80 ? 94 LYS Q CE 1 +ATOM 31186 N NZ . LYS Q 1 94 ? 19.117 8.719 34.240 1.00 126.35 ? 94 LYS Q NZ 1 +ATOM 31187 N N . ILE Q 1 95 ? 11.165 8.974 34.141 1.00 69.99 ? 95 ILE Q N 1 +ATOM 31188 C CA . ILE Q 1 95 ? 10.097 9.012 35.140 1.00 74.99 ? 95 ILE Q CA 1 +ATOM 31189 C C . ILE Q 1 95 ? 8.835 8.322 34.624 1.00 80.27 ? 95 ILE Q C 1 +ATOM 31190 O O . ILE Q 1 95 ? 8.145 7.575 35.383 1.00 39.44 ? 95 ILE Q O 1 +ATOM 31191 C CB . ILE Q 1 95 ? 9.715 10.416 35.579 1.00 55.71 ? 95 ILE Q CB 1 +ATOM 31192 C CG1 . ILE Q 1 95 ? 10.939 11.203 35.953 1.00 62.47 ? 95 ILE Q CG1 1 +ATOM 31193 C CG2 . ILE Q 1 95 ? 8.829 10.290 36.807 1.00 65.52 ? 95 ILE Q CG2 1 +ATOM 31194 C CD1 . ILE Q 1 95 ? 10.658 12.477 36.708 1.00 88.92 ? 95 ILE Q CD1 1 +ATOM 31195 N N . ILE Q 1 96 ? 8.596 8.530 33.323 1.00 81.39 ? 96 ILE Q N 1 +ATOM 31196 C CA . ILE Q 1 96 ? 7.543 7.811 32.597 1.00 80.72 ? 96 ILE Q CA 1 +ATOM 31197 C C . ILE Q 1 96 ? 7.747 6.325 32.695 1.00 87.97 ? 96 ILE Q C 1 +ATOM 31198 O O . ILE Q 1 96 ? 6.902 5.613 33.221 1.00 82.74 ? 96 ILE Q O 1 +ATOM 31199 C CB . ILE Q 1 96 ? 7.492 8.190 31.108 1.00 67.64 ? 96 ILE Q CB 1 +ATOM 31200 C CG1 . ILE Q 1 96 ? 7.050 9.642 30.981 1.00 90.74 ? 96 ILE Q CG1 1 +ATOM 31201 C CG2 . ILE Q 1 96 ? 6.486 7.320 30.398 1.00 54.65 ? 96 ILE Q CG2 1 +ATOM 31202 C CD1 . ILE Q 1 96 ? 6.895 10.091 29.551 1.00 109.08 ? 96 ILE Q CD1 1 +ATOM 31203 N N . ARG Q 1 97 ? 8.909 5.862 32.233 1.00 106.36 ? 97 ARG Q N 1 +ATOM 31204 C CA . ARG Q 1 97 ? 9.209 4.418 32.210 1.00 98.71 ? 97 ARG Q CA 1 +ATOM 31205 C C . ARG Q 1 97 ? 9.165 3.784 33.613 1.00 87.77 ? 97 ARG Q C 1 +ATOM 31206 O O . ARG Q 1 97 ? 8.770 2.621 33.768 1.00 66.43 ? 97 ARG Q O 1 +ATOM 31207 C CB . ARG Q 1 97 ? 10.570 4.143 31.576 1.00 100.31 ? 97 ARG Q CB 1 +ATOM 31208 C CG . ARG Q 1 97 ? 10.512 3.650 30.141 1.00 110.95 ? 97 ARG Q CG 1 +ATOM 31209 C CD . ARG Q 1 97 ? 11.908 3.333 29.619 1.00 110.85 ? 97 ARG Q CD 1 +ATOM 31210 N NE . ARG Q 1 97 ? 12.622 4.529 29.176 1.00 84.74 ? 97 ARG Q NE 1 +ATOM 31211 C CZ . ARG Q 1 97 ? 12.697 4.931 27.907 1.00 86.14 ? 97 ARG Q CZ 1 +ATOM 31212 N NH1 . ARG Q 1 97 ? 12.117 4.242 26.913 1.00 69.76 ? 97 ARG Q NH1 1 +ATOM 31213 N NH2 . ARG Q 1 97 ? 13.369 6.033 27.618 1.00 95.94 ? 97 ARG Q NH2 1 +ATOM 31214 N N . ALA Q 1 98 ? 9.507 4.572 34.631 1.00 64.19 ? 98 ALA Q N 1 +ATOM 31215 C CA . ALA Q 1 98 ? 9.433 4.098 35.991 1.00 64.61 ? 98 ALA Q CA 1 +ATOM 31216 C C . ALA Q 1 98 ? 7.983 4.015 36.468 1.00 67.77 ? 98 ALA Q C 1 +ATOM 31217 O O . ALA Q 1 98 ? 7.639 3.201 37.343 1.00 45.56 ? 98 ALA Q O 1 +ATOM 31218 C CB . ALA Q 1 98 ? 10.262 4.996 36.887 1.00 57.96 ? 98 ALA Q CB 1 +ATOM 31219 N N . ALA Q 1 99 ? 7.149 4.900 35.915 1.00 90.38 ? 99 ALA Q N 1 +ATOM 31220 C CA . ALA Q 1 99 ? 5.729 4.968 36.275 1.00 96.60 ? 99 ALA Q CA 1 +ATOM 31221 C C . ALA Q 1 99 ? 4.972 3.722 35.825 1.00 80.35 ? 99 ALA Q C 1 +ATOM 31222 O O . ALA Q 1 99 ? 4.234 3.110 36.585 1.00 48.10 ? 99 ALA Q O 1 +ATOM 31223 C CB . ALA Q 1 99 ? 5.087 6.232 35.691 1.00 81.33 ? 99 ALA Q CB 1 +ATOM 31224 N N . GLN Q 1 100 ? 5.137 3.387 34.556 1.00 112.23 ? 100 GLN Q N 1 +ATOM 31225 C CA . GLN Q 1 100 ? 4.208 2.479 33.882 1.00 134.17 ? 100 GLN Q CA 1 +ATOM 31226 C C . GLN Q 1 100 ? 4.797 1.107 33.621 1.00 125.30 ? 100 GLN Q C 1 +ATOM 31227 O O . GLN Q 1 100 ? 4.154 0.273 32.971 1.00 143.17 ? 100 GLN Q O 1 +ATOM 31228 C CB . GLN Q 1 100 ? 3.688 3.095 32.564 1.00 138.55 ? 100 GLN Q CB 1 +ATOM 31229 C CG . GLN Q 1 100 ? 4.736 3.803 31.713 1.00 110.06 ? 100 GLN Q CG 1 +ATOM 31230 C CD . GLN Q 1 100 ? 4.183 4.925 30.846 1.00 97.52 ? 100 GLN Q CD 1 +ATOM 31231 O OE1 . GLN Q 1 100 ? 3.558 5.890 31.326 1.00 95.08 ? 100 GLN Q OE1 1 +ATOM 31232 N NE2 . GLN Q 1 100 ? 4.373 4.777 29.547 1.00 115.72 ? 100 GLN Q NE2 1 +ATOM 31233 N N . GLU Q 1 101 ? 5.997 0.861 34.146 1.00 98.76 ? 101 GLU Q N 1 +ATOM 31234 C CA . GLU Q 1 101 ? 6.653 -0.439 33.953 1.00 110.00 ? 101 GLU Q CA 1 +ATOM 31235 C C . GLU Q 1 101 ? 5.931 -1.622 34.645 1.00 102.43 ? 101 GLU Q C 1 +ATOM 31236 O O . GLU Q 1 101 ? 6.051 -2.765 34.203 1.00 72.30 ? 101 GLU Q O 1 +ATOM 31237 C CB . GLU Q 1 101 ? 8.109 -0.383 34.407 1.00 98.21 ? 101 GLU Q CB 1 +ATOM 31238 C CG . GLU Q 1 101 ? 8.307 0.125 35.822 1.00 115.70 ? 101 GLU Q CG 1 +ATOM 31239 C CD . GLU Q 1 101 ? 9.769 0.099 36.260 1.00 112.08 ? 101 GLU Q CD 1 +ATOM 31240 O OE1 . GLU Q 1 101 ? 10.641 -0.018 35.378 1.00 93.30 ? 101 GLU Q OE1 1 +ATOM 31241 O OE2 . GLU Q 1 101 ? 10.031 0.142 37.491 1.00 93.38 ? 101 GLU Q OE2 1 +ATOM 31242 N N . ASN Q 1 102 ? 5.152 -1.333 35.685 1.00 80.03 ? 102 ASN Q N 1 +ATOM 31243 C CA . ASN Q 1 102 ? 4.458 -2.370 36.409 1.00 63.32 ? 102 ASN Q CA 1 +ATOM 31244 C C . ASN Q 1 102 ? 3.035 -2.633 35.892 1.00 93.08 ? 102 ASN Q C 1 +ATOM 31245 O O . ASN Q 1 102 ? 2.335 -3.527 36.399 1.00 79.90 ? 102 ASN Q O 1 +ATOM 31246 C CB . ASN Q 1 102 ? 4.374 -2.006 37.877 1.00 54.45 ? 102 ASN Q CB 1 +ATOM 31247 C CG . ASN Q 1 102 ? 5.668 -2.125 38.568 1.00 50.48 ? 102 ASN Q CG 1 +ATOM 31248 O OD1 . ASN Q 1 102 ? 6.180 -3.242 38.808 1.00 59.65 ? 102 ASN Q OD1 1 +ATOM 31249 N ND2 . ASN Q 1 102 ? 6.294 -0.972 38.805 1.00 61.55 ? 102 ASN Q ND2 1 +ATOM 31250 N N . GLY Q 1 103 ? 2.582 -1.861 34.903 1.00 115.31 ? 103 GLY Q N 1 +ATOM 31251 C CA . GLY Q 1 103 ? 1.229 -2.048 34.356 1.00 111.30 ? 103 GLY Q CA 1 +ATOM 31252 C C . GLY Q 1 103 ? 0.114 -1.866 35.376 1.00 85.52 ? 103 GLY Q C 1 +ATOM 31253 O O . GLY Q 1 103 ? -0.921 -2.541 35.321 1.00 88.53 ? 103 GLY Q O 1 +ATOM 31254 N N . THR Q 1 104 ? 0.332 -0.970 36.319 1.00 67.75 ? 104 THR Q N 1 +ATOM 31255 C CA . THR Q 1 104 ? -0.733 -0.542 37.178 1.00 79.94 ? 104 THR Q CA 1 +ATOM 31256 C C . THR Q 1 104 ? -1.257 0.793 36.693 1.00 100.61 ? 104 THR Q C 1 +ATOM 31257 O O . THR Q 1 104 ? -2.443 1.078 36.881 1.00 168.26 ? 104 THR Q O 1 +ATOM 31258 C CB . THR Q 1 104 ? -0.298 -0.416 38.648 1.00 90.96 ? 104 THR Q CB 1 +ATOM 31259 O OG1 . THR Q 1 104 ? 0.693 0.614 38.802 1.00 104.61 ? 104 THR Q OG1 1 +ATOM 31260 C CG2 . THR Q 1 104 ? 0.253 -1.746 39.144 1.00 89.33 ? 104 THR Q CG2 1 +ATOM 31261 N N . VAL Q 1 105 ? -0.426 1.585 36.009 1.00 104.01 ? 105 VAL Q N 1 +ATOM 31262 C CA . VAL Q 1 105 ? -0.834 2.944 35.630 1.00 115.32 ? 105 VAL Q CA 1 +ATOM 31263 C C . VAL Q 1 105 ? -2.083 2.944 34.740 1.00 117.68 ? 105 VAL Q C 1 +ATOM 31264 O O . VAL Q 1 105 ? -2.262 2.075 33.878 1.00 122.12 ? 105 VAL Q O 1 +ATOM 31265 C CB . VAL Q 1 105 ? 0.301 3.769 34.971 1.00 141.24 ? 105 VAL Q CB 1 +ATOM 31266 C CG1 . VAL Q 1 105 ? -0.240 4.760 33.935 1.00 145.44 ? 105 VAL Q CG1 1 +ATOM 31267 C CG2 . VAL Q 1 105 ? 1.108 4.530 36.031 1.00 159.14 ? 105 VAL Q CG2 1 +ATOM 31268 N N . ALA Q 1 106 ? -2.972 3.895 35.026 1.00 123.45 ? 106 ALA Q N 1 +ATOM 31269 C CA . ALA Q 1 106 ? -4.307 3.945 34.443 1.00 123.44 ? 106 ALA Q CA 1 +ATOM 31270 C C . ALA Q 1 106 ? -4.216 4.118 32.937 1.00 113.83 ? 106 ALA Q C 1 +ATOM 31271 O O . ALA Q 1 106 ? -3.466 4.965 32.447 1.00 136.90 ? 106 ALA Q O 1 +ATOM 31272 C CB . ALA Q 1 106 ? -5.109 5.085 35.075 1.00 126.88 ? 106 ALA Q CB 1 +ATOM 31273 N N . ILE Q 1 107 ? -5.011 3.336 32.211 1.00 114.60 ? 107 ILE Q N 1 +ATOM 31274 C CA . ILE Q 1 107 ? -4.953 3.302 30.746 1.00 137.76 ? 107 ILE Q CA 1 +ATOM 31275 C C . ILE Q 1 107 ? -5.195 4.681 30.081 1.00 136.52 ? 107 ILE Q C 1 +ATOM 31276 O O . ILE Q 1 107 ? -4.651 4.983 29.019 1.00 103.33 ? 107 ILE Q O 1 +ATOM 31277 C CB . ILE Q 1 107 ? -5.946 2.248 30.191 1.00 137.19 ? 107 ILE Q CB 1 +ATOM 31278 C CG1 . ILE Q 1 107 ? -5.673 1.962 28.709 1.00 134.23 ? 107 ILE Q CG1 1 +ATOM 31279 C CG2 . ILE Q 1 107 ? -7.391 2.698 30.396 1.00 140.79 ? 107 ILE Q CG2 1 +ATOM 31280 C CD1 . ILE Q 1 107 ? -4.264 1.486 28.402 1.00 103.08 ? 107 ILE Q CD1 1 +ATOM 31281 N N . ASN Q 1 108 ? -6.008 5.512 30.725 1.00 154.26 ? 108 ASN Q N 1 +ATOM 31282 C CA . ASN Q 1 108 ? -6.240 6.888 30.277 1.00 158.96 ? 108 ASN Q CA 1 +ATOM 31283 C C . ASN Q 1 108 ? -5.001 7.753 30.482 1.00 161.04 ? 108 ASN Q C 1 +ATOM 31284 O O . ASN Q 1 108 ? -4.721 8.661 29.702 1.00 219.76 ? 108 ASN Q O 1 +ATOM 31285 C CB . ASN Q 1 108 ? -7.410 7.518 31.049 1.00 174.77 ? 108 ASN Q CB 1 +ATOM 31286 C CG . ASN Q 1 108 ? -8.450 6.498 31.476 1.00 201.60 ? 108 ASN Q CG 1 +ATOM 31287 O OD1 . ASN Q 1 108 ? -9.362 6.170 30.717 1.00 236.63 ? 108 ASN Q OD1 1 +ATOM 31288 N ND2 . ASN Q 1 108 ? -8.311 5.982 32.695 1.00 198.65 ? 108 ASN Q ND2 1 +ATOM 31289 N N . ASN Q 1 109 ? -4.292 7.486 31.570 1.00 153.85 ? 109 ASN Q N 1 +ATOM 31290 C CA . ASN Q 1 109 ? -3.154 8.295 31.991 1.00 151.66 ? 109 ASN Q CA 1 +ATOM 31291 C C . ASN Q 1 109 ? -1.843 7.865 31.333 1.00 149.31 ? 109 ASN Q C 1 +ATOM 31292 O O . ASN Q 1 109 ? -0.865 8.623 31.323 1.00 158.93 ? 109 ASN Q O 1 +ATOM 31293 C CB . ASN Q 1 109 ? -3.006 8.222 33.512 1.00 154.66 ? 109 ASN Q CB 1 +ATOM 31294 C CG . ASN Q 1 109 ? -3.216 9.564 34.181 1.00 165.46 ? 109 ASN Q CG 1 +ATOM 31295 O OD1 . ASN Q 1 109 ? -2.285 10.131 34.749 1.00 169.16 ? 109 ASN Q OD1 1 +ATOM 31296 N ND2 . ASN Q 1 109 ? -4.426 10.103 34.074 1.00 166.87 ? 109 ASN Q ND2 1 +ATOM 31297 N N . ARG Q 1 110 ? -1.848 6.660 30.761 1.00 131.59 ? 110 ARG Q N 1 +ATOM 31298 C CA . ARG Q 1 110 ? -0.647 6.032 30.188 1.00 106.32 ? 110 ARG Q CA 1 +ATOM 31299 C C . ARG Q 1 110 ? 0.003 6.922 29.121 1.00 102.22 ? 110 ARG Q C 1 +ATOM 31300 O O . ARG Q 1 110 ? -0.686 7.460 28.256 1.00 95.03 ? 110 ARG Q O 1 +ATOM 31301 C CB . ARG Q 1 110 ? -1.031 4.675 29.565 1.00 93.27 ? 110 ARG Q CB 1 +ATOM 31302 C CG . ARG Q 1 110 ? 0.101 3.673 29.453 1.00 89.06 ? 110 ARG Q CG 1 +ATOM 31303 C CD . ARG Q 1 110 ? -0.380 2.243 29.650 1.00 83.25 ? 110 ARG Q CD 1 +ATOM 31304 N NE . ARG Q 1 110 ? -0.810 1.624 28.391 1.00 99.83 ? 110 ARG Q NE 1 +ATOM 31305 C CZ . ARG Q 1 110 ? -0.225 0.557 27.815 1.00 108.44 ? 110 ARG Q CZ 1 +ATOM 31306 N NH1 . ARG Q 1 110 ? 0.790 -0.089 28.406 1.00 91.32 ? 110 ARG Q NH1 1 +ATOM 31307 N NH2 . ARG Q 1 110 ? -0.664 0.124 26.629 1.00 93.32 ? 110 ARG Q NH2 1 +ATOM 31308 N N . ILE Q 1 111 ? 1.325 7.075 29.178 1.00 93.89 ? 111 ILE Q N 1 +ATOM 31309 C CA . ILE Q 1 111 ? 2.046 7.786 28.123 1.00 88.53 ? 111 ILE Q CA 1 +ATOM 31310 C C . ILE Q 1 111 ? 2.842 6.820 27.282 1.00 84.85 ? 111 ILE Q C 1 +ATOM 31311 O O . ILE Q 1 111 ? 3.768 6.203 27.788 1.00 92.77 ? 111 ILE Q O 1 +ATOM 31312 C CB . ILE Q 1 111 ? 3.000 8.831 28.692 1.00 89.63 ? 111 ILE Q CB 1 +ATOM 31313 C CG1 . ILE Q 1 111 ? 2.196 9.902 29.436 1.00 119.29 ? 111 ILE Q CG1 1 +ATOM 31314 C CG2 . ILE Q 1 111 ? 3.810 9.469 27.568 1.00 86.72 ? 111 ILE Q CG2 1 +ATOM 31315 C CD1 . ILE Q 1 111 ? 3.033 10.838 30.292 1.00 149.05 ? 111 ILE Q CD1 1 +ATOM 31316 N N . PRO Q 1 112 ? 2.495 6.691 25.990 1.00 94.15 ? 112 PRO Q N 1 +ATOM 31317 C CA . PRO Q 1 112 ? 3.216 5.777 25.123 1.00 103.07 ? 112 PRO Q CA 1 +ATOM 31318 C C . PRO Q 1 112 ? 4.560 6.363 24.674 1.00 120.56 ? 112 PRO Q C 1 +ATOM 31319 O O . PRO Q 1 112 ? 4.623 7.506 24.190 1.00 113.68 ? 112 PRO Q O 1 +ATOM 31320 C CB . PRO Q 1 112 ? 2.273 5.621 23.935 1.00 104.14 ? 112 PRO Q CB 1 +ATOM 31321 C CG . PRO Q 1 112 ? 1.598 6.950 23.828 1.00 109.24 ? 112 PRO Q CG 1 +ATOM 31322 C CD . PRO Q 1 112 ? 1.570 7.544 25.220 1.00 112.24 ? 112 PRO Q CD 1 +ATOM 31323 N N . LEU Q 1 113 ? 5.620 5.583 24.851 1.00 115.35 ? 113 LEU Q N 1 +ATOM 31324 C CA . LEU Q 1 113 ? 6.960 6.064 24.597 1.00 105.34 ? 113 LEU Q CA 1 +ATOM 31325 C C . LEU Q 1 113 ? 7.525 5.495 23.310 1.00 108.70 ? 113 LEU Q C 1 +ATOM 31326 O O . LEU Q 1 113 ? 7.381 4.318 22.992 1.00 140.02 ? 113 LEU Q O 1 +ATOM 31327 C CB . LEU Q 1 113 ? 7.880 5.758 25.782 1.00 96.77 ? 113 LEU Q CB 1 +ATOM 31328 C CG . LEU Q 1 113 ? 7.883 6.805 26.900 1.00 86.95 ? 113 LEU Q CG 1 +ATOM 31329 C CD1 . LEU Q 1 113 ? 8.905 6.393 27.924 1.00 79.44 ? 113 LEU Q CD1 1 +ATOM 31330 C CD2 . LEU Q 1 113 ? 8.201 8.199 26.370 1.00 100.67 ? 113 LEU Q CD2 1 +ATOM 31331 N N . GLN Q 1 114 ? 8.245 6.350 22.612 1.00 97.61 ? 114 GLN Q N 1 +ATOM 31332 C CA . GLN Q 1 114 ? 8.674 6.086 21.270 1.00 103.92 ? 114 GLN Q CA 1 +ATOM 31333 C C . GLN Q 1 114 ? 10.098 6.564 21.253 1.00 111.34 ? 114 GLN Q C 1 +ATOM 31334 O O . GLN Q 1 114 ? 10.438 7.528 21.954 1.00 169.74 ? 114 GLN Q O 1 +ATOM 31335 C CB . GLN Q 1 114 ? 7.814 6.891 20.295 1.00 103.65 ? 114 GLN Q CB 1 +ATOM 31336 C CG . GLN Q 1 114 ? 7.651 6.278 18.915 1.00 116.22 ? 114 GLN Q CG 1 +ATOM 31337 C CD . GLN Q 1 114 ? 7.330 7.343 17.862 1.00 110.44 ? 114 GLN Q CD 1 +ATOM 31338 O OE1 . GLN Q 1 114 ? 6.765 8.384 18.193 1.00 85.39 ? 114 GLN Q OE1 1 +ATOM 31339 N NE2 . GLN Q 1 114 ? 7.727 7.103 16.610 1.00 97.60 ? 114 GLN Q NE2 1 +ATOM 31340 N N . SER Q 1 115 ? 10.934 5.916 20.460 1.00 88.27 ? 115 SER Q N 1 +ATOM 31341 C CA . SER Q 1 115 ? 12.356 6.267 20.429 1.00 88.22 ? 115 SER Q CA 1 +ATOM 31342 C C . SER Q 1 115 ? 12.556 7.714 20.031 1.00 70.10 ? 115 SER Q C 1 +ATOM 31343 O O . SER Q 1 115 ? 11.638 8.307 19.387 1.00 96.23 ? 115 SER Q O 1 +ATOM 31344 C CB . SER Q 1 115 ? 13.064 5.375 19.424 1.00 112.08 ? 115 SER Q CB 1 +ATOM 31345 O OG . SER Q 1 115 ? 12.380 5.366 18.158 1.00 54.42 ? 115 SER Q OG 1 +ATOM 31346 N N . LEU Q 1 116 ? 13.678 8.325 20.426 1.00 42.12 ? 116 LEU Q N 1 +ATOM 31347 C CA . LEU Q 1 116 ? 13.729 9.764 20.244 1.00 53.39 ? 116 LEU Q CA 1 +ATOM 31348 C C . LEU Q 1 116 ? 13.928 10.028 18.782 1.00 57.18 ? 116 LEU Q C 1 +ATOM 31349 O O . LEU Q 1 116 ? 14.817 9.447 18.173 1.00 46.05 ? 116 LEU Q O 1 +ATOM 31350 C CB . LEU Q 1 116 ? 14.842 10.416 21.020 1.00 76.49 ? 116 LEU Q CB 1 +ATOM 31351 C CG . LEU Q 1 116 ? 14.723 10.357 22.545 1.00 103.95 ? 116 LEU Q CG 1 +ATOM 31352 C CD1 . LEU Q 1 116 ? 15.476 9.165 23.116 1.00 94.74 ? 116 LEU Q CD1 1 +ATOM 31353 C CD2 . LEU Q 1 116 ? 15.258 11.677 23.098 1.00 137.62 ? 116 LEU Q CD2 1 +ATOM 31354 N N . THR Q 1 117 ? 13.016 10.795 18.180 1.00 84.90 ? 117 THR Q N 1 +ATOM 31355 C CA . THR Q 1 117 ? 13.078 11.096 16.755 1.00 112.33 ? 117 THR Q CA 1 +ATOM 31356 C C . THR Q 1 117 ? 14.444 11.713 16.483 1.00 125.89 ? 117 THR Q C 1 +ATOM 31357 O O . THR Q 1 117 ? 14.867 12.611 17.206 1.00 93.52 ? 117 THR Q O 1 +ATOM 31358 C CB . THR Q 1 117 ? 11.982 12.098 16.330 1.00 135.05 ? 117 THR Q CB 1 +ATOM 31359 O OG1 . THR Q 1 117 ? 10.697 11.572 16.687 1.00 100.39 ? 117 THR Q OG1 1 +ATOM 31360 C CG2 . THR Q 1 117 ? 12.003 12.309 14.822 1.00 167.27 ? 117 THR Q CG2 1 +ATOM 31361 N N . ALA Q 1 118 ? 15.097 11.255 15.413 1.00 126.66 ? 118 ALA Q N 1 +ATOM 31362 C CA . ALA Q 1 118 ? 16.498 11.585 15.161 1.00 94.34 ? 118 ALA Q CA 1 +ATOM 31363 C C . ALA Q 1 118 ? 16.656 12.367 13.902 1.00 76.99 ? 118 ALA Q C 1 +ATOM 31364 O O . ALA Q 1 118 ? 16.018 12.059 12.868 1.00 64.18 ? 118 ALA Q O 1 +ATOM 31365 C CB . ALA Q 1 118 ? 17.330 10.326 15.078 1.00 114.94 ? 118 ALA Q CB 1 +ATOM 31366 N N . ALA Q 1 119 ? 17.535 13.353 13.984 1.00 66.38 ? 119 ALA Q N 1 +ATOM 31367 C CA . ALA Q 1 119 ? 17.737 14.297 12.889 1.00 83.22 ? 119 ALA Q CA 1 +ATOM 31368 C C . ALA Q 1 119 ? 18.710 13.774 11.816 1.00 87.17 ? 119 ALA Q C 1 +ATOM 31369 O O . ALA Q 1 119 ? 19.568 12.947 12.114 1.00 67.46 ? 119 ALA Q O 1 +ATOM 31370 C CB . ALA Q 1 119 ? 18.244 15.597 13.451 1.00 79.67 ? 119 ALA Q CB 1 +ATOM 31371 N N . ASN Q 1 120 ? 18.598 14.285 10.587 1.00 88.64 ? 120 ASN Q N 1 +ATOM 31372 C CA . ASN Q 1 120 ? 19.570 13.945 9.562 1.00 96.13 ? 120 ASN Q CA 1 +ATOM 31373 C C . ASN Q 1 120 ? 20.640 15.011 9.403 1.00 114.01 ? 120 ASN Q C 1 +ATOM 31374 O O . ASN Q 1 120 ? 21.827 14.717 9.236 1.00 124.84 ? 120 ASN Q O 1 +ATOM 31375 C CB . ASN Q 1 120 ? 18.916 13.708 8.207 1.00 107.66 ? 120 ASN Q CB 1 +ATOM 31376 C CG . ASN Q 1 120 ? 19.936 13.272 7.153 1.00 136.35 ? 120 ASN Q CG 1 +ATOM 31377 O OD1 . ASN Q 1 120 ? 19.858 13.701 6.003 1.00 173.35 ? 120 ASN Q OD1 1 +ATOM 31378 N ND2 . ASN Q 1 120 ? 20.934 12.451 7.551 1.00 125.12 ? 120 ASN Q ND2 1 +ATOM 31379 N N . ILE Q 1 121 ? 20.211 16.263 9.326 1.00 98.12 ? 121 ILE Q N 1 +ATOM 31380 C CA . ILE Q 1 121 ? 21.164 17.357 9.278 1.00 67.11 ? 121 ILE Q CA 1 +ATOM 31381 C C . ILE Q 1 121 ? 21.034 18.083 10.572 1.00 62.88 ? 121 ILE Q C 1 +ATOM 31382 O O . ILE Q 1 121 ? 19.958 18.221 11.118 1.00 46.31 ? 121 ILE Q O 1 +ATOM 31383 C CB . ILE Q 1 121 ? 20.950 18.312 8.080 1.00 60.02 ? 121 ILE Q CB 1 +ATOM 31384 C CG1 . ILE Q 1 121 ? 19.707 19.202 8.266 1.00 60.68 ? 121 ILE Q CG1 1 +ATOM 31385 C CG2 . ILE Q 1 121 ? 20.878 17.528 6.757 1.00 59.37 ? 121 ILE Q CG2 1 +ATOM 31386 C CD1 . ILE Q 1 121 ? 20.013 20.670 8.494 1.00 52.63 ? 121 ILE Q CD1 1 +ATOM 31387 N N . MET Q 1 122 ? 22.160 18.508 11.106 1.00 100.67 ? 122 MET Q N 1 +ATOM 31388 C CA . MET Q 1 122 ? 22.114 19.442 12.206 1.00 122.20 ? 122 MET Q CA 1 +ATOM 31389 C C . MET Q 1 122 ? 22.861 20.723 11.847 1.00 111.69 ? 122 MET Q C 1 +ATOM 31390 O O . MET Q 1 122 ? 23.796 20.706 11.068 1.00 116.38 ? 122 MET Q O 1 +ATOM 31391 C CB . MET Q 1 122 ? 22.670 18.794 13.468 1.00 123.27 ? 122 MET Q CB 1 +ATOM 31392 C CG . MET Q 1 122 ? 24.094 18.285 13.360 1.00 107.57 ? 122 MET Q CG 1 +ATOM 31393 S SD . MET Q 1 122 ? 24.867 18.314 14.967 1.00 80.92 ? 122 MET Q SD 1 +ATOM 31394 C CE . MET Q 1 122 ? 26.499 18.937 14.593 1.00 85.03 ? 122 MET Q CE 1 +ATOM 31395 N N . VAL Q 1 123 ? 22.325 21.846 12.288 1.00 87.25 ? 123 VAL Q N 1 +ATOM 31396 C CA . VAL Q 1 123 ? 22.880 23.131 11.936 1.00 79.62 ? 123 VAL Q CA 1 +ATOM 31397 C C . VAL Q 1 123 ? 23.350 23.812 13.203 1.00 87.94 ? 123 VAL Q C 1 +ATOM 31398 O O . VAL Q 1 123 ? 22.592 24.008 14.132 1.00 84.31 ? 123 VAL Q O 1 +ATOM 31399 C CB . VAL Q 1 123 ? 21.879 24.043 11.203 1.00 82.73 ? 123 VAL Q CB 1 +ATOM 31400 C CG1 . VAL Q 1 123 ? 20.488 23.941 11.804 1.00 94.26 ? 123 VAL Q CG1 1 +ATOM 31401 C CG2 . VAL Q 1 123 ? 22.353 25.502 11.215 1.00 107.05 ? 123 VAL Q CG2 1 +ATOM 31402 N N . GLU Q 1 124 ? 24.602 24.235 13.196 1.00 107.55 ? 124 GLU Q N 1 +ATOM 31403 C CA . GLU Q 1 124 ? 25.128 25.055 14.270 1.00 111.37 ? 124 GLU Q CA 1 +ATOM 31404 C C . GLU Q 1 124 ? 25.788 26.293 13.717 1.00 114.44 ? 124 GLU Q C 1 +ATOM 31405 O O . GLU Q 1 124 ? 26.012 26.423 12.521 1.00 117.99 ? 124 GLU Q O 1 +ATOM 31406 C CB . GLU Q 1 124 ? 26.126 24.271 15.125 1.00 138.24 ? 124 GLU Q CB 1 +ATOM 31407 C CG . GLU Q 1 124 ? 26.897 23.176 14.406 1.00 140.13 ? 124 GLU Q CG 1 +ATOM 31408 C CD . GLU Q 1 124 ? 27.518 22.185 15.381 1.00 140.87 ? 124 GLU Q CD 1 +ATOM 31409 O OE1 . GLU Q 1 124 ? 26.906 21.888 16.421 1.00 100.40 ? 124 GLU Q OE1 1 +ATOM 31410 O OE2 . GLU Q 1 124 ? 28.625 21.715 15.097 1.00 146.54 ? 124 GLU Q OE2 1 +ATOM 31411 N N . GLY Q 1 125 ? 26.122 27.208 14.609 1.00 120.04 ? 125 GLY Q N 1 +ATOM 31412 C CA . GLY Q 1 125 ? 26.712 28.473 14.204 1.00 109.66 ? 125 GLY Q CA 1 +ATOM 31413 C C . GLY Q 1 125 ? 27.202 29.269 15.385 1.00 104.69 ? 125 GLY Q C 1 +ATOM 31414 O O . GLY Q 1 125 ? 27.384 28.740 16.484 1.00 105.40 ? 125 GLY Q O 1 +ATOM 31415 N N . SER Q 1 126 ? 27.373 30.564 15.177 1.00 100.09 ? 126 SER Q N 1 +ATOM 31416 C CA . SER Q 1 126 ? 27.948 31.402 16.212 1.00 114.79 ? 126 SER Q CA 1 +ATOM 31417 C C . SER Q 1 126 ? 27.628 32.847 15.931 1.00 105.12 ? 126 SER Q C 1 +ATOM 31418 O O . SER Q 1 126 ? 27.493 33.248 14.782 1.00 158.36 ? 126 SER Q O 1 +ATOM 31419 C CB . SER Q 1 126 ? 29.470 31.250 16.249 1.00 132.01 ? 126 SER Q CB 1 +ATOM 31420 O OG . SER Q 1 126 ? 29.901 29.950 15.852 1.00 125.79 ? 126 SER Q OG 1 +ATOM 31421 N N . ILE Q 1 127 ? 27.487 33.639 16.978 1.00 83.76 ? 127 ILE Q N 1 +ATOM 31422 C CA . ILE Q 1 127 ? 27.464 35.068 16.798 1.00 64.64 ? 127 ILE Q CA 1 +ATOM 31423 C C . ILE Q 1 127 ? 28.925 35.405 16.644 1.00 63.19 ? 127 ILE Q C 1 +ATOM 31424 O O . ILE Q 1 127 ? 29.637 35.578 17.617 1.00 69.22 ? 127 ILE Q O 1 +ATOM 31425 C CB . ILE Q 1 127 ? 26.769 35.844 17.943 1.00 57.40 ? 127 ILE Q CB 1 +ATOM 31426 C CG1 . ILE Q 1 127 ? 25.251 35.525 17.987 1.00 56.22 ? 127 ILE Q CG1 1 +ATOM 31427 C CG2 . ILE Q 1 127 ? 26.967 37.354 17.796 1.00 46.39 ? 127 ILE Q CG2 1 +ATOM 31428 C CD1 . ILE Q 1 127 ? 24.661 35.570 19.397 1.00 62.20 ? 127 ILE Q CD1 1 +ATOM 31429 N N . ILE Q 1 128 ? 29.307 35.663 15.402 1.00 82.54 ? 128 ILE Q N 1 +ATOM 31430 C CA . ILE Q 1 128 ? 30.632 36.160 15.061 1.00 113.91 ? 128 ILE Q CA 1 +ATOM 31431 C C . ILE Q 1 128 ? 30.613 37.707 15.056 1.00 119.75 ? 128 ILE Q C 1 +ATOM 31432 O O . ILE Q 1 128 ? 30.041 38.357 14.178 1.00 177.68 ? 128 ILE Q O 1 +ATOM 31433 C CB . ILE Q 1 128 ? 31.060 35.577 13.708 1.00 128.57 ? 128 ILE Q CB 1 +ATOM 31434 C CG1 . ILE Q 1 128 ? 30.028 35.904 12.624 1.00 131.41 ? 128 ILE Q CG1 1 +ATOM 31435 C CG2 . ILE Q 1 128 ? 31.109 34.057 13.800 1.00 123.07 ? 128 ILE Q CG2 1 +ATOM 31436 C CD1 . ILE Q 1 128 ? 30.624 35.886 11.231 1.00 182.74 ? 128 ILE Q CD1 1 +ATOM 31437 N N . GLY Q 1 129 ? 31.054 38.288 16.165 1.00 96.91 ? 129 GLY Q N 1 +ATOM 31438 C CA . GLY Q 1 129 ? 31.305 39.703 16.212 1.00 101.18 ? 129 GLY Q CA 1 +ATOM 31439 C C . GLY Q 1 129 ? 30.134 40.617 16.569 1.00 115.61 ? 129 GLY Q C 1 +ATOM 31440 O O . GLY Q 1 129 ? 29.027 40.543 16.003 1.00 142.14 ? 129 GLY Q O 1 +ATOM 31441 N N . TYR Q 1 130 ? 30.453 41.596 17.405 1.00 125.47 ? 130 TYR Q N 1 +ATOM 31442 C CA . TYR Q 1 130 ? 29.662 42.824 17.548 1.00 99.38 ? 130 TYR Q CA 1 +ATOM 31443 C C . TYR Q 1 130 ? 30.655 43.970 17.688 1.00 101.70 ? 130 TYR Q C 1 +ATOM 31444 O O . TYR Q 1 130 ? 31.371 44.041 18.671 1.00 156.84 ? 130 TYR Q O 1 +ATOM 31445 C CB . TYR Q 1 130 ? 28.780 42.715 18.785 1.00 69.90 ? 130 TYR Q CB 1 +ATOM 31446 C CG . TYR Q 1 130 ? 28.000 43.942 19.143 1.00 71.63 ? 130 TYR Q CG 1 +ATOM 31447 C CD1 . TYR Q 1 130 ? 28.630 45.089 19.594 1.00 80.46 ? 130 TYR Q CD1 1 +ATOM 31448 C CD2 . TYR Q 1 130 ? 26.606 43.921 19.128 1.00 97.03 ? 130 TYR Q CD2 1 +ATOM 31449 C CE1 . TYR Q 1 130 ? 27.893 46.215 19.954 1.00 99.55 ? 130 TYR Q CE1 1 +ATOM 31450 C CE2 . TYR Q 1 130 ? 25.858 45.034 19.496 1.00 99.87 ? 130 TYR Q CE2 1 +ATOM 31451 C CZ . TYR Q 1 130 ? 26.503 46.183 19.889 1.00 83.39 ? 130 TYR Q CZ 1 +ATOM 31452 O OH . TYR Q 1 130 ? 25.740 47.267 20.246 1.00 49.01 ? 130 TYR Q OH 1 +ATOM 31453 N N . GLU Q 1 131 ? 30.806 44.773 16.645 1.00 98.37 ? 131 GLU Q N 1 +ATOM 31454 C CA . GLU Q 1 131 ? 31.573 45.995 16.757 1.00 89.26 ? 131 GLU Q CA 1 +ATOM 31455 C C . GLU Q 1 131 ? 30.614 47.149 17.100 1.00 95.16 ? 131 GLU Q C 1 +ATOM 31456 O O . GLU Q 1 131 ? 29.457 47.154 16.664 1.00 64.01 ? 131 GLU Q O 1 +ATOM 31457 C CB . GLU Q 1 131 ? 32.321 46.230 15.458 1.00 97.56 ? 131 GLU Q CB 1 +ATOM 31458 C CG . GLU Q 1 131 ? 33.349 47.350 15.496 1.00 124.13 ? 131 GLU Q CG 1 +ATOM 31459 C CD . GLU Q 1 131 ? 34.724 46.903 15.982 1.00 138.11 ? 131 GLU Q CD 1 +ATOM 31460 O OE1 . GLU Q 1 131 ? 35.082 45.722 15.786 1.00 121.03 ? 131 GLU Q OE1 1 +ATOM 31461 O OE2 . GLU Q 1 131 ? 35.462 47.754 16.526 1.00 150.89 ? 131 GLU Q OE2 1 +ATOM 31462 N N . SER Q 1 132 ? 31.101 48.128 17.857 1.00 97.08 ? 132 SER Q N 1 +ATOM 31463 C CA . SER Q 1 132 ? 30.231 49.182 18.368 1.00 106.98 ? 132 SER Q CA 1 +ATOM 31464 C C . SER Q 1 132 ? 30.657 50.583 17.883 1.00 135.68 ? 132 SER Q C 1 +ATOM 31465 O O . SER Q 1 132 ? 31.848 50.883 17.789 1.00 145.86 ? 132 SER Q O 1 +ATOM 31466 C CB . SER Q 1 132 ? 30.207 49.136 19.887 1.00 102.01 ? 132 SER Q CB 1 +ATOM 31467 O OG . SER Q 1 132 ? 30.832 50.286 20.440 1.00 133.91 ? 132 SER Q OG 1 +ATOM 31468 N N . ASN Q 1 133 ? 29.669 51.438 17.598 1.00 134.73 ? 133 ASN Q N 1 +ATOM 31469 C CA . ASN Q 1 133 ? 29.896 52.729 16.917 1.00 101.38 ? 133 ASN Q CA 1 +ATOM 31470 C C . ASN Q 1 133 ? 30.787 52.568 15.701 1.00 121.50 ? 133 ASN Q C 1 +ATOM 31471 O O . ASN Q 1 133 ? 31.849 53.189 15.595 1.00 101.36 ? 133 ASN Q O 1 +ATOM 31472 C CB . ASN Q 1 133 ? 30.502 53.749 17.858 1.00 93.38 ? 133 ASN Q CB 1 +ATOM 31473 C CG . ASN Q 1 133 ? 29.610 54.042 19.041 1.00 130.39 ? 133 ASN Q CG 1 +ATOM 31474 O OD1 . ASN Q 1 133 ? 28.378 53.913 18.978 1.00 122.40 ? 133 ASN Q OD1 1 +ATOM 31475 N ND2 . ASN Q 1 133 ? 30.235 54.380 20.159 1.00 159.77 ? 133 ASN Q ND2 1 +ATOM 31476 N N . VAL Q 1 134 ? 30.341 51.712 14.782 1.00 146.86 ? 134 VAL Q N 1 +ATOM 31477 C CA . VAL Q 1 134 ? 31.068 51.435 13.549 1.00 149.06 ? 134 VAL Q CA 1 +ATOM 31478 C C . VAL Q 1 134 ? 30.994 52.696 12.695 1.00 148.75 ? 134 VAL Q C 1 +ATOM 31479 O O . VAL Q 1 134 ? 31.966 53.066 12.026 1.00 104.79 ? 134 VAL Q O 1 +ATOM 31480 C CB . VAL Q 1 134 ? 30.462 50.224 12.801 1.00 117.64 ? 134 VAL Q CB 1 +ATOM 31481 C CG1 . VAL Q 1 134 ? 31.279 49.902 11.561 1.00 129.62 ? 134 VAL Q CG1 1 +ATOM 31482 C CG2 . VAL Q 1 134 ? 30.433 49.004 13.719 1.00 157.04 ? 134 VAL Q CG2 1 +ATOM 31483 N N . LYS Q 1 135 ? 29.859 53.389 12.796 1.00 143.28 ? 135 LYS Q N 1 +ATOM 31484 C CA . LYS Q 1 135 ? 29.764 54.777 12.343 1.00 126.60 ? 135 LYS Q CA 1 +ATOM 31485 C C . LYS Q 1 135 ? 28.973 55.648 13.304 1.00 94.63 ? 135 LYS Q C 1 +ATOM 31486 O O . LYS Q 1 135 ? 28.235 55.155 14.168 1.00 63.19 ? 135 LYS Q O 1 +ATOM 31487 C CB . LYS Q 1 135 ? 29.069 54.846 10.994 1.00 189.93 ? 135 LYS Q CB 1 +ATOM 31488 C CG . LYS Q 1 135 ? 29.806 54.117 9.884 1.00 250.27 ? 135 LYS Q CG 1 +ATOM 31489 C CD . LYS Q 1 135 ? 28.989 54.139 8.605 1.00 252.12 ? 135 LYS Q CD 1 +ATOM 31490 C CE . LYS Q 1 135 ? 29.692 53.404 7.483 1.00 226.39 ? 135 LYS Q CE 1 +ATOM 31491 N NZ . LYS Q 1 135 ? 29.160 53.841 6.170 1.00 227.83 ? 135 LYS Q NZ 1 +ATOM 31492 N N . SER Q 1 136 ? 29.204 56.949 13.198 1.00 107.12 ? 136 SER Q N 1 +ATOM 31493 C CA . SER Q 1 136 ? 28.579 57.906 14.092 1.00 129.89 ? 136 SER Q CA 1 +ATOM 31494 C C . SER Q 1 136 ? 28.689 59.315 13.549 1.00 143.87 ? 136 SER Q C 1 +ATOM 31495 O O . SER Q 1 136 ? 29.596 59.629 12.774 1.00 119.27 ? 136 SER Q O 1 +ATOM 31496 C CB . SER Q 1 136 ? 29.186 57.840 15.506 1.00 157.97 ? 136 SER Q CB 1 +ATOM 31497 O OG . SER Q 1 136 ? 29.656 59.103 15.952 1.00 179.04 ? 136 SER Q OG 1 +ATOM 31498 N N . GLY Q 1 137 ? 27.767 60.168 13.983 1.00 156.63 ? 137 GLY Q N 1 +ATOM 31499 C CA . GLY Q 1 137 ? 27.787 61.571 13.584 1.00 162.20 ? 137 GLY Q CA 1 +ATOM 31500 C C . GLY Q 1 137 ? 26.852 62.452 14.397 1.00 133.47 ? 137 GLY Q C 1 +ATOM 31501 O O . GLY Q 1 137 ? 26.122 61.975 15.254 1.00 82.35 ? 137 GLY Q O 1 +ATOM 31502 N N . GLY Q 1 138 ? 26.936 63.755 14.160 1.00 123.03 ? 138 GLY Q N 1 +ATOM 31503 C CA . GLY Q 1 138 ? 26.094 64.704 14.855 1.00 113.88 ? 138 GLY Q CA 1 +ATOM 31504 C C . GLY Q 1 138 ? 26.039 66.035 14.147 1.00 143.15 ? 138 GLY Q C 1 +ATOM 31505 O O . GLY Q 1 138 ? 27.031 66.484 13.554 1.00 143.21 ? 138 GLY Q O 1 +ATOM 31506 N N . VAL Q 1 139 ? 24.867 66.665 14.192 1.00 151.50 ? 139 VAL Q N 1 +ATOM 31507 C CA . VAL Q 1 139 ? 24.689 68.000 13.625 1.00 138.28 ? 139 VAL Q CA 1 +ATOM 31508 C C . VAL Q 1 139 ? 23.845 68.855 14.570 1.00 119.90 ? 139 VAL Q C 1 +ATOM 31509 O O . VAL Q 1 139 ? 22.735 68.476 14.937 1.00 81.40 ? 139 VAL Q O 1 +ATOM 31510 C CB . VAL Q 1 139 ? 24.005 67.953 12.245 1.00 121.15 ? 139 VAL Q CB 1 +ATOM 31511 C CG1 . VAL Q 1 139 ? 23.725 69.361 11.758 1.00 137.13 ? 139 VAL Q CG1 1 +ATOM 31512 C CG2 . VAL Q 1 139 ? 24.860 67.198 11.238 1.00 104.51 ? 139 VAL Q CG2 1 +ATOM 31513 N N . GLY Q 1 140 ? 24.386 70.011 14.940 1.00 115.63 ? 140 GLY Q N 1 +ATOM 31514 C CA . GLY Q 1 140 ? 23.718 70.903 15.863 1.00 111.46 ? 140 GLY Q CA 1 +ATOM 31515 C C . GLY Q 1 140 ? 24.041 72.365 15.625 1.00 138.24 ? 140 GLY Q C 1 +ATOM 31516 O O . GLY Q 1 140 ? 25.154 72.733 15.229 1.00 108.74 ? 140 GLY Q O 1 +ATOM 31517 N N . ALA Q 1 141 ? 23.053 73.214 15.870 1.00 173.58 ? 141 ALA Q N 1 +ATOM 31518 C CA . ALA Q 1 141 ? 23.237 74.657 15.733 1.00 179.12 ? 141 ALA Q CA 1 +ATOM 31519 C C . ALA Q 1 141 ? 22.463 75.432 16.803 1.00 193.01 ? 141 ALA Q C 1 +ATOM 31520 O O . ALA Q 1 141 ? 21.347 75.065 17.176 1.00 163.69 ? 141 ALA Q O 1 +ATOM 31521 C CB . ALA Q 1 141 ? 22.836 75.116 14.339 1.00 135.08 ? 141 ALA Q CB 1 +ATOM 31522 N N . ARG Q 1 142 ? 23.092 76.475 17.326 1.00 182.23 ? 142 ARG Q N 1 +ATOM 31523 C CA . ARG Q 1 142 ? 22.412 77.383 18.213 1.00 168.03 ? 142 ARG Q CA 1 +ATOM 31524 C C . ARG Q 1 142 ? 22.609 78.796 17.701 1.00 198.04 ? 142 ARG Q C 1 +ATOM 31525 O O . ARG Q 1 142 ? 23.661 79.126 17.149 1.00 212.41 ? 142 ARG Q O 1 +ATOM 31526 C CB . ARG Q 1 142 ? 22.918 77.244 19.649 1.00 159.37 ? 142 ARG Q CB 1 +ATOM 31527 C CG . ARG Q 1 142 ? 22.157 78.122 20.640 1.00 179.81 ? 142 ARG Q CG 1 +ATOM 31528 C CD . ARG Q 1 142 ? 21.840 77.418 21.951 1.00 194.90 ? 142 ARG Q CD 1 +ATOM 31529 N NE . ARG Q 1 142 ? 22.919 77.527 22.929 1.00 205.94 ? 142 ARG Q NE 1 +ATOM 31530 C CZ . ARG Q 1 142 ? 23.130 76.675 23.929 1.00 203.47 ? 142 ARG Q CZ 1 +ATOM 31531 N NH1 . ARG Q 1 142 ? 22.367 75.596 24.066 1.00 204.92 ? 142 ARG Q NH1 1 +ATOM 31532 N NH2 . ARG Q 1 142 ? 24.132 76.887 24.778 1.00 182.62 ? 142 ARG Q NH2 1 +ATOM 31533 N N . TYR Q 1 143 ? 21.573 79.615 17.860 1.00 215.83 ? 143 TYR Q N 1 +ATOM 31534 C CA . TYR Q 1 143 ? 21.546 80.962 17.303 1.00 191.18 ? 143 TYR Q CA 1 +ATOM 31535 C C . TYR Q 1 143 ? 21.129 81.988 18.365 1.00 148.37 ? 143 TYR Q C 1 +ATOM 31536 O O . TYR Q 1 143 ? 19.959 82.378 18.466 1.00 122.59 ? 143 TYR Q O 1 +ATOM 31537 C CB . TYR Q 1 143 ? 20.594 81.004 16.101 1.00 194.47 ? 143 TYR Q CB 1 +ATOM 31538 C CG . TYR Q 1 143 ? 20.616 82.318 15.383 1.00 199.37 ? 143 TYR Q CG 1 +ATOM 31539 C CD1 . TYR Q 1 143 ? 21.729 82.706 14.650 1.00 189.07 ? 143 TYR Q CD1 1 +ATOM 31540 C CD2 . TYR Q 1 143 ? 19.551 83.203 15.488 1.00 199.88 ? 143 TYR Q CD2 1 +ATOM 31541 C CE1 . TYR Q 1 143 ? 21.773 83.934 14.025 1.00 200.78 ? 143 TYR Q CE1 1 +ATOM 31542 C CE2 . TYR Q 1 143 ? 19.580 84.436 14.866 1.00 189.99 ? 143 TYR Q CE2 1 +ATOM 31543 C CZ . TYR Q 1 143 ? 20.696 84.797 14.138 1.00 208.37 ? 143 TYR Q CZ 1 +ATOM 31544 O OH . TYR Q 1 143 ? 20.740 86.026 13.524 1.00 256.38 ? 143 TYR Q OH 1 +ATOM 31545 N N . GLY Q 1 145 ? 19.997 82.325 20.812 1.00 140.10 ? 145 GLY Q N 1 +ATOM 31546 C CA . GLY Q 1 145 ? 19.173 81.891 21.928 1.00 152.25 ? 145 GLY Q CA 1 +ATOM 31547 C C . GLY Q 1 145 ? 18.502 80.538 21.718 1.00 214.59 ? 145 GLY Q C 1 +ATOM 31548 O O . GLY Q 1 145 ? 18.176 79.863 22.694 1.00 221.31 ? 145 GLY Q O 1 +ATOM 31549 N N . ILE Q 1 146 ? 18.299 80.132 20.460 1.00 259.49 ? 146 ILE Q N 1 +ATOM 31550 C CA . ILE Q 1 146 ? 17.510 78.926 20.120 1.00 235.27 ? 146 ILE Q CA 1 +ATOM 31551 C C . ILE Q 1 146 ? 18.429 77.883 19.473 1.00 232.31 ? 146 ILE Q C 1 +ATOM 31552 O O . ILE Q 1 146 ? 19.271 78.232 18.648 1.00 193.86 ? 146 ILE Q O 1 +ATOM 31553 C CB . ILE Q 1 146 ? 16.340 79.251 19.146 1.00 182.45 ? 146 ILE Q CB 1 +ATOM 31554 C CG1 . ILE Q 1 146 ? 15.691 80.595 19.511 1.00 185.48 ? 146 ILE Q CG1 1 +ATOM 31555 C CG2 . ILE Q 1 146 ? 15.299 78.141 19.163 1.00 136.51 ? 146 ILE Q CG2 1 +ATOM 31556 C CD1 . ILE Q 1 146 ? 16.203 81.775 18.707 1.00 163.36 ? 146 ILE Q CD1 1 +ATOM 31557 N N . GLY Q 1 147 ? 18.289 76.614 19.856 1.00 214.63 ? 147 GLY Q N 1 +ATOM 31558 C CA . GLY Q 1 147 ? 19.197 75.583 19.353 1.00 176.86 ? 147 GLY Q CA 1 +ATOM 31559 C C . GLY Q 1 147 ? 18.620 74.187 19.239 1.00 164.95 ? 147 GLY Q C 1 +ATOM 31560 O O . GLY Q 1 147 ? 17.667 73.827 19.917 1.00 114.65 ? 147 GLY Q O 1 +ATOM 31561 N N . ALA Q 1 148 ? 19.193 73.406 18.335 1.00 180.29 ? 148 ALA Q N 1 +ATOM 31562 C CA . ALA Q 1 148 ? 18.823 72.005 18.192 1.00 172.18 ? 148 ALA Q CA 1 +ATOM 31563 C C . ALA Q 1 148 ? 20.027 71.189 17.747 1.00 174.16 ? 148 ALA Q C 1 +ATOM 31564 O O . ALA Q 1 148 ? 21.060 71.743 17.348 1.00 138.66 ? 148 ALA Q O 1 +ATOM 31565 C CB . ALA Q 1 148 ? 17.671 71.845 17.208 1.00 141.35 ? 148 ALA Q CB 1 +ATOM 31566 N N . ASP Q 1 149 ? 19.901 69.873 17.861 1.00 169.13 ? 149 ASP Q N 1 +ATOM 31567 C CA . ASP Q 1 149 ? 20.961 68.984 17.430 1.00 159.10 ? 149 ASP Q CA 1 +ATOM 31568 C C . ASP Q 1 149 ? 20.449 67.551 17.332 1.00 136.15 ? 149 ASP Q C 1 +ATOM 31569 O O . ASP Q 1 149 ? 19.567 67.135 18.093 1.00 93.13 ? 149 ASP Q O 1 +ATOM 31570 C CB . ASP Q 1 149 ? 22.168 69.076 18.379 1.00 181.14 ? 149 ASP Q CB 1 +ATOM 31571 C CG . ASP Q 1 149 ? 21.985 68.269 19.633 1.00 194.33 ? 149 ASP Q CG 1 +ATOM 31572 O OD1 . ASP Q 1 149 ? 21.221 68.708 20.511 1.00 172.77 ? 149 ASP Q OD1 1 +ATOM 31573 O OD2 . ASP Q 1 149 ? 22.616 67.203 19.748 1.00 200.54 ? 149 ASP Q OD2 1 +ATOM 31574 N N . THR Q 1 150 ? 21.004 66.796 16.394 1.00 129.76 ? 150 THR Q N 1 +ATOM 31575 C CA . THR Q 1 150 ? 20.848 65.345 16.426 1.00 137.74 ? 150 THR Q CA 1 +ATOM 31576 C C . THR Q 1 150 ? 22.211 64.678 16.457 1.00 145.15 ? 150 THR Q C 1 +ATOM 31577 O O . THR Q 1 150 ? 23.231 65.262 16.055 1.00 90.74 ? 150 THR Q O 1 +ATOM 31578 C CB . THR Q 1 150 ? 20.072 64.796 15.216 1.00 131.72 ? 150 THR Q CB 1 +ATOM 31579 O OG1 . THR Q 1 150 ? 20.763 65.156 14.009 1.00 194.46 ? 150 THR Q OG1 1 +ATOM 31580 C CG2 . THR Q 1 150 ? 18.672 65.330 15.195 1.00 104.39 ? 150 THR Q CG2 1 +ATOM 31581 N N . GLN Q 1 151 ? 22.216 63.455 16.968 1.00 153.67 ? 151 GLN Q N 1 +ATOM 31582 C CA . GLN Q 1 151 ? 23.395 62.637 16.990 1.00 171.44 ? 151 GLN Q CA 1 +ATOM 31583 C C . GLN Q 1 151 ? 23.014 61.216 16.696 1.00 145.00 ? 151 GLN Q C 1 +ATOM 31584 O O . GLN Q 1 151 ? 21.956 60.781 17.097 1.00 81.37 ? 151 GLN Q O 1 +ATOM 31585 C CB . GLN Q 1 151 ? 23.951 62.758 18.383 1.00 198.31 ? 151 GLN Q CB 1 +ATOM 31586 C CG . GLN Q 1 151 ? 25.309 62.184 18.683 1.00 219.02 ? 151 GLN Q CG 1 +ATOM 31587 C CD . GLN Q 1 151 ? 25.813 62.753 19.991 1.00 197.52 ? 151 GLN Q CD 1 +ATOM 31588 O OE1 . GLN Q 1 151 ? 25.017 63.003 20.895 1.00 142.00 ? 151 GLN Q OE1 1 +ATOM 31589 N NE2 . GLN Q 1 151 ? 27.107 63.048 20.066 1.00 193.13 ? 151 GLN Q NE2 1 +ATOM 31590 N N . TYR Q 1 152 ? 23.844 60.509 15.942 1.00 142.76 ? 152 TYR Q N 1 +ATOM 31591 C CA . TYR Q 1 152 ? 23.538 59.130 15.620 1.00 142.88 ? 152 TYR Q CA 1 +ATOM 31592 C C . TYR Q 1 152 ? 24.744 58.234 15.739 1.00 153.94 ? 152 TYR Q C 1 +ATOM 31593 O O . TYR Q 1 152 ? 25.882 58.670 15.499 1.00 129.64 ? 152 TYR Q O 1 +ATOM 31594 C CB . TYR Q 1 152 ? 22.922 59.035 14.229 1.00 139.17 ? 152 TYR Q CB 1 +ATOM 31595 C CG . TYR Q 1 152 ? 23.817 58.525 13.115 1.00 146.65 ? 152 TYR Q CG 1 +ATOM 31596 C CD1 . TYR Q 1 152 ? 24.930 59.232 12.683 1.00 141.42 ? 152 TYR Q CD1 1 +ATOM 31597 C CD2 . TYR Q 1 152 ? 23.486 57.365 12.437 1.00 164.20 ? 152 TYR Q CD2 1 +ATOM 31598 C CE1 . TYR Q 1 152 ? 25.740 58.739 11.665 1.00 151.13 ? 152 TYR Q CE1 1 +ATOM 31599 C CE2 . TYR Q 1 152 ? 24.247 56.897 11.371 1.00 154.49 ? 152 TYR Q CE2 1 +ATOM 31600 C CZ . TYR Q 1 152 ? 25.385 57.578 10.996 1.00 149.43 ? 152 TYR Q CZ 1 +ATOM 31601 O OH . TYR Q 1 152 ? 26.163 57.079 9.961 1.00 132.16 ? 152 TYR Q OH 1 +ATOM 31602 N N . GLN Q 1 153 ? 24.503 56.994 16.162 1.00 139.27 ? 153 GLN Q N 1 +ATOM 31603 C CA . GLN Q 1 153 ? 25.553 55.984 16.137 1.00 162.36 ? 153 GLN Q CA 1 +ATOM 31604 C C . GLN Q 1 153 ? 25.006 54.672 15.595 1.00 118.76 ? 153 GLN Q C 1 +ATOM 31605 O O . GLN Q 1 153 ? 23.807 54.427 15.658 1.00 65.41 ? 153 GLN Q O 1 +ATOM 31606 C CB . GLN Q 1 153 ? 26.125 55.777 17.542 1.00 211.46 ? 153 GLN Q CB 1 +ATOM 31607 C CG . GLN Q 1 153 ? 26.868 56.985 18.137 1.00 222.56 ? 153 GLN Q CG 1 +ATOM 31608 C CD . GLN Q 1 153 ? 27.305 56.725 19.590 1.00 205.06 ? 153 GLN Q CD 1 +ATOM 31609 O OE1 . GLN Q 1 153 ? 26.749 55.851 20.274 1.00 240.15 ? 153 GLN Q OE1 1 +ATOM 31610 N NE2 . GLN Q 1 153 ? 28.281 57.492 20.069 1.00 166.77 ? 153 GLN Q NE2 1 +ATOM 31611 N N . LEU Q 1 154 ? 25.885 53.865 15.002 1.00 119.09 ? 154 LEU Q N 1 +ATOM 31612 C CA . LEU Q 1 154 ? 25.470 52.543 14.564 1.00 137.96 ? 154 LEU Q CA 1 +ATOM 31613 C C . LEU Q 1 154 ? 26.553 51.483 14.747 1.00 181.09 ? 154 LEU Q C 1 +ATOM 31614 O O . LEU Q 1 154 ? 27.757 51.736 14.548 1.00 161.43 ? 154 LEU Q O 1 +ATOM 31615 C CB . LEU Q 1 154 ? 24.991 52.566 13.112 1.00 144.19 ? 154 LEU Q CB 1 +ATOM 31616 C CG . LEU Q 1 154 ? 26.083 52.747 12.049 1.00 193.41 ? 154 LEU Q CG 1 +ATOM 31617 C CD1 . LEU Q 1 154 ? 26.560 51.411 11.501 1.00 194.17 ? 154 LEU Q CD1 1 +ATOM 31618 C CD2 . LEU Q 1 154 ? 25.558 53.640 10.935 1.00 249.99 ? 154 LEU Q CD2 1 +ATOM 31619 N N . ASP Q 1 155 ? 26.075 50.272 15.040 1.00 195.06 ? 155 ASP Q N 1 +ATOM 31620 C CA . ASP Q 1 155 ? 26.897 49.132 15.469 1.00 156.14 ? 155 ASP Q CA 1 +ATOM 31621 C C . ASP Q 1 155 ? 26.715 47.986 14.466 1.00 117.73 ? 155 ASP Q C 1 +ATOM 31622 O O . ASP Q 1 155 ? 25.717 47.963 13.744 1.00 72.91 ? 155 ASP Q O 1 +ATOM 31623 C CB . ASP Q 1 155 ? 26.472 48.687 16.884 1.00 139.54 ? 155 ASP Q CB 1 +ATOM 31624 C CG . ASP Q 1 155 ? 26.322 49.857 17.854 1.00 167.05 ? 155 ASP Q CG 1 +ATOM 31625 O OD1 . ASP Q 1 155 ? 25.288 50.567 17.794 1.00 177.44 ? 155 ASP Q OD1 1 +ATOM 31626 O OD2 . ASP Q 1 155 ? 27.261 50.100 18.635 1.00 160.03 ? 155 ASP Q OD2 1 +ATOM 31627 N N . GLN Q 1 156 ? 27.640 47.026 14.453 1.00 118.12 ? 156 GLN Q N 1 +ATOM 31628 C CA . GLN Q 1 156 ? 27.528 45.841 13.584 1.00 123.86 ? 156 GLN Q CA 1 +ATOM 31629 C C . GLN Q 1 156 ? 27.375 44.517 14.368 1.00 131.34 ? 156 GLN Q C 1 +ATOM 31630 O O . GLN Q 1 156 ? 27.699 44.436 15.545 1.00 173.18 ? 156 GLN Q O 1 +ATOM 31631 C CB . GLN Q 1 156 ? 28.752 45.740 12.692 1.00 94.04 ? 156 GLN Q CB 1 +ATOM 31632 C CG . GLN Q 1 156 ? 28.624 44.727 11.570 1.00 121.78 ? 156 GLN Q CG 1 +ATOM 31633 C CD . GLN Q 1 156 ? 29.679 44.916 10.488 1.00 130.21 ? 156 GLN Q CD 1 +ATOM 31634 O OE1 . GLN Q 1 156 ? 30.514 45.830 10.577 1.00 127.37 ? 156 GLN Q OE1 1 +ATOM 31635 N NE2 . GLN Q 1 156 ? 29.528 44.179 9.382 1.00 124.87 ? 156 GLN Q NE2 1 +ATOM 31636 N N . ILE Q 1 157 ? 26.767 43.524 13.732 1.00 90.43 ? 157 ILE Q N 1 +ATOM 31637 C CA . ILE Q 1 157 ? 26.580 42.237 14.330 1.00 62.09 ? 157 ILE Q CA 1 +ATOM 31638 C C . ILE Q 1 157 ? 26.596 41.213 13.196 1.00 62.42 ? 157 ILE Q C 1 +ATOM 31639 O O . ILE Q 1 157 ? 26.002 41.438 12.126 1.00 129.80 ? 157 ILE Q O 1 +ATOM 31640 C CB . ILE Q 1 157 ? 25.274 42.191 15.158 1.00 57.82 ? 157 ILE Q CB 1 +ATOM 31641 C CG1 . ILE Q 1 157 ? 25.356 41.070 16.206 1.00 110.36 ? 157 ILE Q CG1 1 +ATOM 31642 C CG2 . ILE Q 1 157 ? 24.073 41.929 14.285 1.00 61.53 ? 157 ILE Q CG2 1 +ATOM 31643 C CD1 . ILE Q 1 157 ? 24.205 41.043 17.200 1.00 125.55 ? 157 ILE Q CD1 1 +ATOM 31644 N N . ALA Q 1 158 ? 27.258 40.088 13.394 1.00 65.30 ? 158 ALA Q N 1 +ATOM 31645 C CA . ALA Q 1 158 ? 27.342 39.074 12.341 1.00 93.26 ? 158 ALA Q CA 1 +ATOM 31646 C C . ALA Q 1 158 ? 27.134 37.682 12.878 1.00 79.07 ? 158 ALA Q C 1 +ATOM 31647 O O . ALA Q 1 158 ? 27.308 37.434 14.056 1.00 90.38 ? 158 ALA Q O 1 +ATOM 31648 C CB . ALA Q 1 158 ? 28.679 39.133 11.628 1.00 114.65 ? 158 ALA Q CB 1 +ATOM 31649 N N . VAL Q 1 159 ? 26.651 36.805 12.006 1.00 72.90 ? 159 VAL Q N 1 +ATOM 31650 C CA . VAL Q 1 159 ? 26.194 35.503 12.433 1.00 64.88 ? 159 VAL Q CA 1 +ATOM 31651 C C . VAL Q 1 159 ? 26.655 34.504 11.398 1.00 53.36 ? 159 VAL Q C 1 +ATOM 31652 O O . VAL Q 1 159 ? 26.299 34.613 10.223 1.00 106.98 ? 159 VAL Q O 1 +ATOM 31653 C CB . VAL Q 1 159 ? 24.630 35.458 12.670 1.00 68.12 ? 159 VAL Q CB 1 +ATOM 31654 C CG1 . VAL Q 1 159 ? 24.090 34.028 12.630 1.00 76.36 ? 159 VAL Q CG1 1 +ATOM 31655 C CG2 . VAL Q 1 159 ? 24.255 36.099 14.012 1.00 63.54 ? 159 VAL Q CG2 1 +ATOM 31656 N N . ASN Q 1 160 ? 27.279 33.453 11.873 1.00 41.24 ? 160 ASN Q N 1 +ATOM 31657 C CA . ASN Q 1 160 ? 27.498 32.280 11.090 1.00 43.44 ? 160 ASN Q CA 1 +ATOM 31658 C C . ASN Q 1 160 ? 26.410 31.242 11.407 1.00 46.94 ? 160 ASN Q C 1 +ATOM 31659 O O . ASN Q 1 160 ? 26.112 30.922 12.577 1.00 29.70 ? 160 ASN Q O 1 +ATOM 31660 C CB . ASN Q 1 160 ? 28.878 31.705 11.391 1.00 55.21 ? 160 ASN Q CB 1 +ATOM 31661 C CG . ASN Q 1 160 ? 29.260 30.555 10.428 1.00 61.49 ? 160 ASN Q CG 1 +ATOM 31662 O OD1 . ASN Q 1 160 ? 30.058 30.720 9.491 1.00 43.01 ? 160 ASN Q OD1 1 +ATOM 31663 N ND2 . ASN Q 1 160 ? 28.676 29.386 10.647 1.00 78.90 ? 160 ASN Q ND2 1 +ATOM 31664 N N . LEU Q 1 161 ? 25.802 30.696 10.354 1.00 61.44 ? 161 LEU Q N 1 +ATOM 31665 C CA . LEU Q 1 161 ? 25.082 29.422 10.457 1.00 65.34 ? 161 LEU Q CA 1 +ATOM 31666 C C . LEU Q 1 161 ? 25.694 28.397 9.494 1.00 55.61 ? 161 LEU Q C 1 +ATOM 31667 O O . LEU Q 1 161 ? 26.136 28.741 8.424 1.00 37.80 ? 161 LEU Q O 1 +ATOM 31668 C CB . LEU Q 1 161 ? 23.605 29.626 10.168 1.00 60.87 ? 161 LEU Q CB 1 +ATOM 31669 C CG . LEU Q 1 161 ? 22.871 30.516 11.151 1.00 82.01 ? 161 LEU Q CG 1 +ATOM 31670 C CD1 . LEU Q 1 161 ? 21.473 30.804 10.627 1.00 139.62 ? 161 LEU Q CD1 1 +ATOM 31671 C CD2 . LEU Q 1 161 ? 22.804 29.848 12.514 1.00 74.84 ? 161 LEU Q CD2 1 +ATOM 31672 N N . ARG Q 1 162 ? 25.642 27.127 9.860 1.00 54.20 ? 162 ARG Q N 1 +ATOM 31673 C CA . ARG Q 1 162 ? 26.132 26.109 8.981 1.00 69.87 ? 162 ARG Q CA 1 +ATOM 31674 C C . ARG Q 1 162 ? 25.458 24.728 9.137 1.00 70.71 ? 162 ARG Q C 1 +ATOM 31675 O O . ARG Q 1 162 ? 25.336 24.204 10.242 1.00 115.75 ? 162 ARG Q O 1 +ATOM 31676 C CB . ARG Q 1 162 ? 27.657 26.022 9.096 1.00 80.64 ? 162 ARG Q CB 1 +ATOM 31677 C CG . ARG Q 1 162 ? 28.235 25.583 10.439 1.00 89.10 ? 162 ARG Q CG 1 +ATOM 31678 C CD . ARG Q 1 162 ? 29.702 25.141 10.264 1.00 82.07 ? 162 ARG Q CD 1 +ATOM 31679 N NE . ARG Q 1 162 ? 30.314 24.508 11.429 1.00 62.74 ? 162 ARG Q NE 1 +ATOM 31680 C CZ . ARG Q 1 162 ? 30.787 25.182 12.465 1.00 78.69 ? 162 ARG Q CZ 1 +ATOM 31681 N NH1 . ARG Q 1 162 ? 30.664 26.522 12.532 1.00 104.27 ? 162 ARG Q NH1 1 +ATOM 31682 N NH2 . ARG Q 1 162 ? 31.349 24.526 13.466 1.00 79.61 ? 162 ARG Q NH2 1 +ATOM 31683 N N . VAL Q 1 163 ? 25.103 24.127 7.995 1.00 66.86 ? 163 VAL Q N 1 +ATOM 31684 C CA . VAL Q 1 163 ? 24.498 22.800 7.940 1.00 65.62 ? 163 VAL Q CA 1 +ATOM 31685 C C . VAL Q 1 163 ? 25.554 21.734 7.894 1.00 55.07 ? 163 VAL Q C 1 +ATOM 31686 O O . VAL Q 1 163 ? 26.378 21.724 6.982 1.00 60.10 ? 163 VAL Q O 1 +ATOM 31687 C CB . VAL Q 1 163 ? 23.673 22.606 6.670 1.00 80.54 ? 163 VAL Q CB 1 +ATOM 31688 C CG1 . VAL Q 1 163 ? 23.091 21.192 6.644 1.00 89.31 ? 163 VAL Q CG1 1 +ATOM 31689 C CG2 . VAL Q 1 163 ? 22.583 23.685 6.569 1.00 96.05 ? 163 VAL Q CG2 1 +ATOM 31690 N N . VAL Q 1 164 ? 25.493 20.829 8.864 1.00 42.38 ? 164 VAL Q N 1 +ATOM 31691 C CA . VAL Q 1 164 ? 26.419 19.736 8.977 1.00 46.72 ? 164 VAL Q CA 1 +ATOM 31692 C C . VAL Q 1 164 ? 25.712 18.435 8.771 1.00 41.96 ? 164 VAL Q C 1 +ATOM 31693 O O . VAL Q 1 164 ? 24.611 18.244 9.269 1.00 39.63 ? 164 VAL Q O 1 +ATOM 31694 C CB . VAL Q 1 164 ? 27.040 19.658 10.356 1.00 64.26 ? 164 VAL Q CB 1 +ATOM 31695 C CG1 . VAL Q 1 164 ? 27.986 18.456 10.444 1.00 95.21 ? 164 VAL Q CG1 1 +ATOM 31696 C CG2 . VAL Q 1 164 ? 27.807 20.928 10.653 1.00 76.07 ? 164 VAL Q CG2 1 +ATOM 31697 N N . ASN Q 1 165 ? 26.327 17.565 7.975 1.00 45.72 ? 165 ASN Q N 1 +ATOM 31698 C CA . ASN Q 1 165 ? 25.711 16.295 7.636 1.00 69.49 ? 165 ASN Q CA 1 +ATOM 31699 C C . ASN Q 1 165 ? 26.072 15.270 8.686 1.00 88.31 ? 165 ASN Q C 1 +ATOM 31700 O O . ASN Q 1 165 ? 27.243 14.961 8.859 1.00 85.09 ? 165 ASN Q O 1 +ATOM 31701 C CB . ASN Q 1 165 ? 26.147 15.786 6.250 1.00 81.91 ? 165 ASN Q CB 1 +ATOM 31702 C CG . ASN Q 1 165 ? 25.334 14.578 5.792 1.00 93.15 ? 165 ASN Q CG 1 +ATOM 31703 O OD1 . ASN Q 1 165 ? 24.359 14.199 6.444 1.00 88.75 ? 165 ASN Q OD1 1 +ATOM 31704 N ND2 . ASN Q 1 165 ? 25.788 13.920 4.738 1.00 94.48 ? 165 ASN Q ND2 1 +ATOM 31705 N N . VAL Q 1 166 ? 25.046 14.742 9.361 1.00 109.34 ? 166 VAL Q N 1 +ATOM 31706 C CA . VAL Q 1 166 ? 25.224 13.808 10.457 1.00 87.11 ? 166 VAL Q CA 1 +ATOM 31707 C C . VAL Q 1 166 ? 25.895 12.562 9.970 1.00 64.84 ? 166 VAL Q C 1 +ATOM 31708 O O . VAL Q 1 166 ? 26.793 12.048 10.630 1.00 105.84 ? 166 VAL Q O 1 +ATOM 31709 C CB . VAL Q 1 166 ? 23.876 13.424 11.088 1.00 90.66 ? 166 VAL Q CB 1 +ATOM 31710 C CG1 . VAL Q 1 166 ? 23.959 12.061 11.778 1.00 87.35 ? 166 VAL Q CG1 1 +ATOM 31711 C CG2 . VAL Q 1 166 ? 23.412 14.533 12.044 1.00 98.19 ? 166 VAL Q CG2 1 +ATOM 31712 N N . SER Q 1 167 ? 25.537 12.152 8.776 1.00 53.21 ? 167 SER Q N 1 +ATOM 31713 C CA . SER Q 1 167 ? 26.033 10.923 8.255 1.00 73.99 ? 167 SER Q CA 1 +ATOM 31714 C C . SER Q 1 167 ? 27.534 10.955 7.892 1.00 63.10 ? 167 SER Q C 1 +ATOM 31715 O O . SER Q 1 167 ? 28.119 9.865 7.643 1.00 98.12 ? 167 SER Q O 1 +ATOM 31716 C CB . SER Q 1 167 ? 25.184 10.508 7.044 1.00 103.52 ? 167 SER Q CB 1 +ATOM 31717 O OG . SER Q 1 167 ? 23.803 10.696 7.319 1.00 110.77 ? 167 SER Q OG 1 +ATOM 31718 N N . THR Q 1 168 ? 28.138 12.142 7.813 1.00 40.62 ? 168 THR Q N 1 +ATOM 31719 C CA . THR Q 1 168 ? 29.532 12.240 7.373 1.00 52.48 ? 168 THR Q CA 1 +ATOM 31720 C C . THR Q 1 168 ? 30.379 13.240 8.119 1.00 61.15 ? 168 THR Q C 1 +ATOM 31721 O O . THR Q 1 168 ? 31.581 13.037 8.370 1.00 92.94 ? 168 THR Q O 1 +ATOM 31722 C CB . THR Q 1 168 ? 29.643 12.650 5.902 1.00 58.81 ? 168 THR Q CB 1 +ATOM 31723 O OG1 . THR Q 1 168 ? 28.845 13.802 5.675 1.00 72.61 ? 168 THR Q OG1 1 +ATOM 31724 C CG2 . THR Q 1 168 ? 29.180 11.513 4.972 1.00 67.97 ? 168 THR Q CG2 1 +ATOM 31725 N N . GLY Q 1 169 ? 29.757 14.314 8.536 1.00 70.63 ? 169 GLY Q N 1 +ATOM 31726 C CA . GLY Q 1 169 ? 30.506 15.338 9.230 1.00 78.25 ? 169 GLY Q CA 1 +ATOM 31727 C C . GLY Q 1 169 ? 30.912 16.383 8.242 1.00 103.86 ? 169 GLY Q C 1 +ATOM 31728 O O . GLY Q 1 169 ? 31.351 17.468 8.638 1.00 176.99 ? 169 GLY Q O 1 +ATOM 31729 N N . GLU Q 1 170 ? 30.739 16.096 6.948 1.00 111.52 ? 170 GLU Q N 1 +ATOM 31730 C CA . GLU Q 1 170 ? 30.839 17.148 5.913 1.00 145.18 ? 170 GLU Q CA 1 +ATOM 31731 C C . GLU Q 1 170 ? 29.905 18.315 6.272 1.00 107.81 ? 170 GLU Q C 1 +ATOM 31732 O O . GLU Q 1 170 ? 28.745 18.106 6.575 1.00 127.88 ? 170 GLU Q O 1 +ATOM 31733 C CB . GLU Q 1 170 ? 30.464 16.620 4.514 1.00 145.55 ? 170 GLU Q CB 1 +ATOM 31734 C CG . GLU Q 1 170 ? 31.535 15.754 3.866 1.00 127.59 ? 170 GLU Q CG 1 +ATOM 31735 C CD . GLU Q 1 170 ? 30.982 14.604 3.047 1.00 148.38 ? 170 GLU Q CD 1 +ATOM 31736 O OE1 . GLU Q 1 170 ? 29.762 14.326 3.133 1.00 194.48 ? 170 GLU Q OE1 1 +ATOM 31737 O OE2 . GLU Q 1 170 ? 31.774 13.930 2.356 1.00 163.87 ? 170 GLU Q OE2 1 +ATOM 31738 N N . ILE Q 1 171 ? 30.439 19.518 6.334 1.00 58.79 ? 171 ILE Q N 1 +ATOM 31739 C CA . ILE Q 1 171 ? 29.601 20.643 6.371 1.00 53.75 ? 171 ILE Q CA 1 +ATOM 31740 C C . ILE Q 1 171 ? 28.970 20.758 4.999 1.00 69.60 ? 171 ILE Q C 1 +ATOM 31741 O O . ILE Q 1 171 ? 29.679 20.826 3.981 1.00 107.18 ? 171 ILE Q O 1 +ATOM 31742 C CB . ILE Q 1 171 ? 30.411 21.874 6.719 1.00 66.40 ? 171 ILE Q CB 1 +ATOM 31743 C CG1 . ILE Q 1 171 ? 30.826 21.808 8.187 1.00 68.10 ? 171 ILE Q CG1 1 +ATOM 31744 C CG2 . ILE Q 1 171 ? 29.603 23.140 6.435 1.00 70.34 ? 171 ILE Q CG2 1 +ATOM 31745 C CD1 . ILE Q 1 171 ? 31.933 22.772 8.537 1.00 81.16 ? 171 ILE Q CD1 1 +ATOM 31746 N N . LEU Q 1 172 ? 27.640 20.848 4.948 1.00 89.91 ? 172 LEU Q N 1 +ATOM 31747 C CA . LEU Q 1 172 ? 26.919 20.952 3.663 1.00 97.88 ? 172 LEU Q CA 1 +ATOM 31748 C C . LEU Q 1 172 ? 26.592 22.399 3.221 1.00 103.28 ? 172 LEU Q C 1 +ATOM 31749 O O . LEU Q 1 172 ? 26.296 22.693 2.034 1.00 56.88 ? 172 LEU Q O 1 +ATOM 31750 C CB . LEU Q 1 172 ? 25.622 20.175 3.708 1.00 84.54 ? 172 LEU Q CB 1 +ATOM 31751 C CG . LEU Q 1 172 ? 25.844 18.645 3.774 1.00 128.38 ? 172 LEU Q CG 1 +ATOM 31752 C CD1 . LEU Q 1 172 ? 24.567 17.785 3.676 1.00 166.35 ? 172 LEU Q CD1 1 +ATOM 31753 C CD2 . LEU Q 1 172 ? 26.928 18.120 2.830 1.00 105.62 ? 172 LEU Q CD2 1 +ATOM 31754 N N . SER Q 1 173 ? 26.774 23.325 4.154 1.00 133.11 ? 173 SER Q N 1 +ATOM 31755 C CA . SER Q 1 173 ? 26.630 24.747 3.837 1.00 138.06 ? 173 SER Q CA 1 +ATOM 31756 C C . SER Q 1 173 ? 27.127 25.629 4.972 1.00 119.03 ? 173 SER Q C 1 +ATOM 31757 O O . SER Q 1 173 ? 26.772 25.397 6.133 1.00 206.42 ? 173 SER Q O 1 +ATOM 31758 C CB . SER Q 1 173 ? 25.160 25.043 3.590 1.00 155.57 ? 173 SER Q CB 1 +ATOM 31759 O OG . SER Q 1 173 ? 24.914 26.423 3.639 1.00 130.59 ? 173 SER Q OG 1 +ATOM 31760 N N . SER Q 1 174 ? 27.918 26.645 4.648 1.00 71.18 ? 174 SER Q N 1 +ATOM 31761 C CA . SER Q 1 174 ? 28.217 27.676 5.619 1.00 86.24 ? 174 SER Q CA 1 +ATOM 31762 C C . SER Q 1 174 ? 27.710 29.009 5.071 1.00 89.71 ? 174 SER Q C 1 +ATOM 31763 O O . SER Q 1 174 ? 27.965 29.333 3.917 1.00 116.26 ? 174 SER Q O 1 +ATOM 31764 C CB . SER Q 1 174 ? 29.732 27.719 5.923 1.00 78.43 ? 174 SER Q CB 1 +ATOM 31765 O OG . SER Q 1 174 ? 30.035 28.557 7.051 1.00 102.84 ? 174 SER Q OG 1 +ATOM 31766 N N . VAL Q 1 175 ? 27.074 29.817 5.924 1.00 69.46 ? 175 VAL Q N 1 +ATOM 31767 C CA . VAL Q 1 175 ? 26.667 31.168 5.542 1.00 57.15 ? 175 VAL Q CA 1 +ATOM 31768 C C . VAL Q 1 175 ? 27.003 32.219 6.613 1.00 81.55 ? 175 VAL Q C 1 +ATOM 31769 O O . VAL Q 1 175 ? 26.929 31.958 7.812 1.00 97.22 ? 175 VAL Q O 1 +ATOM 31770 C CB . VAL Q 1 175 ? 25.167 31.211 5.270 1.00 59.64 ? 175 VAL Q CB 1 +ATOM 31771 C CG1 . VAL Q 1 175 ? 24.834 30.303 4.096 1.00 89.62 ? 175 VAL Q CG1 1 +ATOM 31772 C CG2 . VAL Q 1 175 ? 24.370 30.776 6.479 1.00 54.07 ? 175 VAL Q CG2 1 +ATOM 31773 N N . ASN Q 1 176 ? 27.292 33.442 6.166 1.00 106.18 ? 176 ASN Q N 1 +ATOM 31774 C CA . ASN Q 1 176 ? 27.768 34.526 7.043 1.00 104.53 ? 176 ASN Q CA 1 +ATOM 31775 C C . ASN Q 1 176 ? 26.951 35.815 6.893 1.00 76.75 ? 176 ASN Q C 1 +ATOM 31776 O O . ASN Q 1 176 ? 27.260 36.623 6.034 1.00 90.87 ? 176 ASN Q O 1 +ATOM 31777 C CB . ASN Q 1 176 ? 29.253 34.806 6.700 1.00 129.47 ? 176 ASN Q CB 1 +ATOM 31778 C CG . ASN Q 1 176 ? 30.245 34.091 7.629 1.00 136.12 ? 176 ASN Q CG 1 +ATOM 31779 O OD1 . ASN Q 1 176 ? 31.479 34.398 7.680 1.00 71.80 ? 176 ASN Q OD1 1 +ATOM 31780 N ND2 . ASN Q 1 176 ? 29.703 33.169 8.413 1.00 135.52 ? 176 ASN Q ND2 1 +ATOM 31781 N N . THR Q 1 177 ? 25.941 36.014 7.730 1.00 65.33 ? 177 THR Q N 1 +ATOM 31782 C CA . THR Q 1 177 ? 25.064 37.175 7.617 1.00 102.12 ? 177 THR Q CA 1 +ATOM 31783 C C . THR Q 1 177 ? 25.475 38.300 8.579 1.00 107.82 ? 177 THR Q C 1 +ATOM 31784 O O . THR Q 1 177 ? 26.191 38.058 9.531 1.00 104.94 ? 177 THR Q O 1 +ATOM 31785 C CB . THR Q 1 177 ? 23.583 36.816 7.869 1.00 108.70 ? 177 THR Q CB 1 +ATOM 31786 O OG1 . THR Q 1 177 ? 23.399 36.505 9.253 1.00 136.99 ? 177 THR Q OG1 1 +ATOM 31787 C CG2 . THR Q 1 177 ? 23.143 35.624 7.012 1.00 98.95 ? 177 THR Q CG2 1 +ATOM 31788 N N . SER Q 1 178 ? 25.011 39.524 8.305 1.00 163.28 ? 178 SER Q N 1 +ATOM 31789 C CA . SER Q 1 178 ? 25.407 40.727 9.061 1.00 160.39 ? 178 SER Q CA 1 +ATOM 31790 C C . SER Q 1 178 ? 24.287 41.766 9.093 1.00 130.10 ? 178 SER Q C 1 +ATOM 31791 O O . SER Q 1 178 ? 23.450 41.821 8.210 1.00 168.52 ? 178 SER Q O 1 +ATOM 31792 C CB . SER Q 1 178 ? 26.667 41.386 8.462 1.00 148.85 ? 178 SER Q CB 1 +ATOM 31793 O OG . SER Q 1 178 ? 26.874 42.690 9.004 1.00 103.51 ? 178 SER Q OG 1 +ATOM 31794 N N . LYS Q 1 179 ? 24.318 42.627 10.093 1.00 100.07 ? 179 LYS Q N 1 +ATOM 31795 C CA . LYS Q 1 179 ? 23.211 43.517 10.334 1.00 115.80 ? 179 LYS Q CA 1 +ATOM 31796 C C . LYS Q 1 179 ? 23.674 44.693 11.181 1.00 117.38 ? 179 LYS Q C 1 +ATOM 31797 O O . LYS Q 1 179 ? 24.492 44.551 12.103 1.00 163.49 ? 179 LYS Q O 1 +ATOM 31798 C CB . LYS Q 1 179 ? 22.056 42.757 11.023 1.00 147.72 ? 179 LYS Q CB 1 +ATOM 31799 C CG . LYS Q 1 179 ? 20.667 43.197 10.597 1.00 139.94 ? 179 LYS Q CG 1 +ATOM 31800 C CD . LYS Q 1 179 ? 20.124 44.245 11.551 1.00 148.81 ? 179 LYS Q CD 1 +ATOM 31801 C CE . LYS Q 1 179 ? 18.823 44.817 11.032 1.00 175.31 ? 179 LYS Q CE 1 +ATOM 31802 N NZ . LYS Q 1 179 ? 18.428 46.041 11.773 1.00 206.50 ? 179 LYS Q NZ 1 +ATOM 31803 N N . THR Q 1 180 ? 23.088 45.844 10.909 1.00 129.83 ? 180 THR Q N 1 +ATOM 31804 C CA . THR Q 1 180 ? 23.482 47.072 11.563 1.00 157.49 ? 180 THR Q CA 1 +ATOM 31805 C C . THR Q 1 180 ? 22.421 47.543 12.572 1.00 139.20 ? 180 THR Q C 1 +ATOM 31806 O O . THR Q 1 180 ? 21.227 47.608 12.265 1.00 112.30 ? 180 THR Q O 1 +ATOM 31807 C CB . THR Q 1 180 ? 23.795 48.190 10.536 1.00 198.53 ? 180 THR Q CB 1 +ATOM 31808 O OG1 . THR Q 1 180 ? 23.621 49.476 11.153 1.00 222.58 ? 180 THR Q OG1 1 +ATOM 31809 C CG2 . THR Q 1 180 ? 22.894 48.088 9.315 1.00 205.62 ? 180 THR Q CG2 1 +ATOM 31810 N N . ILE Q 1 181 ? 22.883 47.907 13.767 1.00 149.80 ? 181 ILE Q N 1 +ATOM 31811 C CA . ILE Q 1 181 ? 22.007 48.440 14.820 1.00 149.21 ? 181 ILE Q CA 1 +ATOM 31812 C C . ILE Q 1 181 ? 22.062 49.981 14.890 1.00 163.76 ? 181 ILE Q C 1 +ATOM 31813 O O . ILE Q 1 181 ? 23.117 50.554 15.159 1.00 117.73 ? 181 ILE Q O 1 +ATOM 31814 C CB . ILE Q 1 181 ? 22.369 47.837 16.202 1.00 127.93 ? 181 ILE Q CB 1 +ATOM 31815 C CG1 . ILE Q 1 181 ? 22.414 46.312 16.114 1.00 118.00 ? 181 ILE Q CG1 1 +ATOM 31816 C CG2 . ILE Q 1 181 ? 21.371 48.252 17.271 1.00 111.42 ? 181 ILE Q CG2 1 +ATOM 31817 C CD1 . ILE Q 1 181 ? 23.767 45.741 16.443 1.00 147.54 ? 181 ILE Q CD1 1 +ATOM 31818 N N . LEU Q 1 182 ? 20.915 50.635 14.648 1.00 172.20 ? 182 LEU Q N 1 +ATOM 31819 C CA . LEU Q 1 182 ? 20.801 52.109 14.623 1.00 152.53 ? 182 LEU Q CA 1 +ATOM 31820 C C . LEU Q 1 182 ? 20.407 52.742 15.970 1.00 116.36 ? 182 LEU Q C 1 +ATOM 31821 O O . LEU Q 1 182 ? 19.496 52.269 16.644 1.00 61.16 ? 182 LEU Q O 1 +ATOM 31822 C CB . LEU Q 1 182 ? 19.781 52.548 13.563 1.00 152.79 ? 182 LEU Q CB 1 +ATOM 31823 C CG . LEU Q 1 182 ? 19.557 54.058 13.433 1.00 158.64 ? 182 LEU Q CG 1 +ATOM 31824 C CD1 . LEU Q 1 182 ? 20.828 54.799 13.010 1.00 155.64 ? 182 LEU Q CD1 1 +ATOM 31825 C CD2 . LEU Q 1 182 ? 18.416 54.299 12.461 1.00 159.38 ? 182 LEU Q CD2 1 +ATOM 31826 N N . SER Q 1 183 ? 21.076 53.846 16.302 1.00 127.87 ? 183 SER Q N 1 +ATOM 31827 C CA . SER Q 1 183 ? 20.726 54.655 17.460 1.00 126.77 ? 183 SER Q CA 1 +ATOM 31828 C C . SER Q 1 183 ? 20.811 56.152 17.122 1.00 168.23 ? 183 SER Q C 1 +ATOM 31829 O O . SER Q 1 183 ? 21.697 56.581 16.378 1.00 128.90 ? 183 SER Q O 1 +ATOM 31830 C CB . SER Q 1 183 ? 21.673 54.344 18.599 1.00 115.60 ? 183 SER Q CB 1 +ATOM 31831 O OG . SER Q 1 183 ? 21.994 52.967 18.631 1.00 149.21 ? 183 SER Q OG 1 +ATOM 31832 N N . TYR Q 1 184 ? 19.868 56.940 17.648 1.00 181.46 ? 184 TYR Q N 1 +ATOM 31833 C CA . TYR Q 1 184 ? 19.889 58.395 17.448 1.00 128.84 ? 184 TYR Q CA 1 +ATOM 31834 C C . TYR Q 1 184 ? 19.254 59.204 18.595 1.00 116.67 ? 184 TYR Q C 1 +ATOM 31835 O O . TYR Q 1 184 ? 18.390 58.716 19.341 1.00 74.62 ? 184 TYR Q O 1 +ATOM 31836 C CB . TYR Q 1 184 ? 19.271 58.766 16.102 1.00 87.91 ? 184 TYR Q CB 1 +ATOM 31837 C CG . TYR Q 1 184 ? 17.846 58.328 15.950 1.00 116.36 ? 184 TYR Q CG 1 +ATOM 31838 C CD1 . TYR Q 1 184 ? 16.788 59.109 16.445 1.00 150.95 ? 184 TYR Q CD1 1 +ATOM 31839 C CD2 . TYR Q 1 184 ? 17.534 57.156 15.286 1.00 137.88 ? 184 TYR Q CD2 1 +ATOM 31840 C CE1 . TYR Q 1 184 ? 15.470 58.712 16.306 1.00 135.54 ? 184 TYR Q CE1 1 +ATOM 31841 C CE2 . TYR Q 1 184 ? 16.220 56.749 15.137 1.00 156.98 ? 184 TYR Q CE2 1 +ATOM 31842 C CZ . TYR Q 1 184 ? 15.194 57.535 15.641 1.00 154.62 ? 184 TYR Q CZ 1 +ATOM 31843 O OH . TYR Q 1 184 ? 13.897 57.111 15.515 1.00 179.78 ? 184 TYR Q OH 1 +ATOM 31844 N N . GLU Q 1 185 ? 19.734 60.440 18.725 1.00 127.05 ? 185 GLU Q N 1 +ATOM 31845 C CA . GLU Q 1 185 ? 19.310 61.367 19.766 1.00 167.04 ? 185 GLU Q CA 1 +ATOM 31846 C C . GLU Q 1 185 ? 18.994 62.732 19.169 1.00 190.59 ? 185 GLU Q C 1 +ATOM 31847 O O . GLU Q 1 185 ? 19.884 63.445 18.718 1.00 154.46 ? 185 GLU Q O 1 +ATOM 31848 C CB . GLU Q 1 185 ? 20.371 61.554 20.853 1.00 186.13 ? 185 GLU Q CB 1 +ATOM 31849 C CG . GLU Q 1 185 ? 21.088 60.302 21.304 1.00 205.47 ? 185 GLU Q CG 1 +ATOM 31850 C CD . GLU Q 1 185 ? 21.960 60.572 22.518 1.00 215.04 ? 185 GLU Q CD 1 +ATOM 31851 O OE1 . GLU Q 1 185 ? 22.029 61.743 22.964 1.00 216.77 ? 185 GLU Q OE1 1 +ATOM 31852 O OE2 . GLU Q 1 185 ? 22.552 59.612 23.045 1.00 207.49 ? 185 GLU Q OE2 1 +ATOM 31853 N N . VAL Q 1 186 ? 17.721 63.101 19.215 1.00 202.25 ? 186 VAL Q N 1 +ATOM 31854 C CA . VAL Q 1 186 ? 17.265 64.410 18.768 1.00 178.83 ? 186 VAL Q CA 1 +ATOM 31855 C C . VAL Q 1 186 ? 17.011 65.324 19.974 1.00 160.05 ? 186 VAL Q C 1 +ATOM 31856 O O . VAL Q 1 186 ? 16.458 64.877 20.981 1.00 123.67 ? 186 VAL Q O 1 +ATOM 31857 C CB . VAL Q 1 186 ? 15.983 64.274 17.925 1.00 161.15 ? 186 VAL Q CB 1 +ATOM 31858 C CG1 . VAL Q 1 186 ? 15.623 65.606 17.290 1.00 165.83 ? 186 VAL Q CG1 1 +ATOM 31859 C CG2 . VAL Q 1 186 ? 16.154 63.204 16.859 1.00 142.53 ? 186 VAL Q CG2 1 +ATOM 31860 N N . GLN Q 1 187 ? 17.419 66.591 19.866 1.00 133.17 ? 187 GLN Q N 1 +ATOM 31861 C CA . GLN Q 1 187 ? 17.299 67.524 20.979 1.00 134.78 ? 187 GLN Q CA 1 +ATOM 31862 C C . GLN Q 1 187 ? 17.076 68.944 20.501 1.00 147.91 ? 187 GLN Q C 1 +ATOM 31863 O O . GLN Q 1 187 ? 17.715 69.390 19.550 1.00 101.83 ? 187 GLN Q O 1 +ATOM 31864 C CB . GLN Q 1 187 ? 18.581 67.489 21.811 1.00 152.34 ? 187 GLN Q CB 1 +ATOM 31865 C CG . GLN Q 1 187 ? 18.641 66.413 22.878 1.00 176.83 ? 187 GLN Q CG 1 +ATOM 31866 C CD . GLN Q 1 187 ? 20.062 66.114 23.317 1.00 180.33 ? 187 GLN Q CD 1 +ATOM 31867 O OE1 . GLN Q 1 187 ? 20.892 67.023 23.416 1.00 151.47 ? 187 GLN Q OE1 1 +ATOM 31868 N NE2 . GLN Q 1 187 ? 20.363 64.830 23.553 1.00 173.16 ? 187 GLN Q NE2 1 +ATOM 31869 N N . ALA Q 1 188 ? 16.200 69.668 21.194 1.00 173.53 ? 188 ALA Q N 1 +ATOM 31870 C CA . ALA Q 1 188 ? 15.975 71.087 20.903 1.00 171.86 ? 188 ALA Q CA 1 +ATOM 31871 C C . ALA Q 1 188 ? 15.775 71.884 22.190 1.00 180.35 ? 188 ALA Q C 1 +ATOM 31872 O O . ALA Q 1 188 ? 15.147 71.398 23.118 1.00 163.13 ? 188 ALA Q O 1 +ATOM 31873 C CB . ALA Q 1 188 ? 14.782 71.249 19.974 1.00 136.30 ? 188 ALA Q CB 1 +ATOM 31874 N N . GLY Q 1 189 ? 16.340 73.088 22.253 1.00 174.95 ? 189 GLY Q N 1 +ATOM 31875 C CA . GLY Q 1 189 ? 16.239 73.933 23.434 1.00 168.90 ? 189 GLY Q CA 1 +ATOM 31876 C C . GLY Q 1 189 ? 16.145 75.409 23.116 1.00 182.89 ? 189 GLY Q C 1 +ATOM 31877 O O . GLY Q 1 189 ? 16.811 75.899 22.208 1.00 149.09 ? 189 GLY Q O 1 +ATOM 31878 N N . VAL Q 1 190 ? 15.266 76.108 23.826 1.00 217.76 ? 190 VAL Q N 1 +ATOM 31879 C CA . VAL Q 1 190 ? 15.071 77.543 23.628 1.00 229.97 ? 190 VAL Q CA 1 +ATOM 31880 C C . VAL Q 1 190 ? 15.489 78.297 24.897 1.00 225.78 ? 190 VAL Q C 1 +ATOM 31881 O O . VAL Q 1 190 ? 15.164 77.882 26.008 1.00 184.47 ? 190 VAL Q O 1 +ATOM 31882 C CB . VAL Q 1 190 ? 13.601 77.877 23.281 1.00 206.53 ? 190 VAL Q CB 1 +ATOM 31883 C CG1 . VAL Q 1 190 ? 13.480 79.327 22.839 1.00 194.48 ? 190 VAL Q CG1 1 +ATOM 31884 C CG2 . VAL Q 1 190 ? 13.062 76.936 22.204 1.00 177.21 ? 190 VAL Q CG2 1 +ATOM 31885 N N . PHE Q 1 191 ? 16.229 79.390 24.726 1.00 230.85 ? 191 PHE Q N 1 +ATOM 31886 C CA . PHE Q 1 191 ? 16.857 80.078 25.855 1.00 221.72 ? 191 PHE Q CA 1 +ATOM 31887 C C . PHE Q 1 191 ? 16.622 81.583 25.752 1.00 183.09 ? 191 PHE Q C 1 +ATOM 31888 O O . PHE Q 1 191 ? 16.872 82.173 24.695 1.00 185.73 ? 191 PHE Q O 1 +ATOM 31889 C CB . PHE Q 1 191 ? 18.365 79.754 25.894 1.00 232.11 ? 191 PHE Q CB 1 +ATOM 31890 C CG . PHE Q 1 191 ? 19.007 79.975 27.239 1.00 243.08 ? 191 PHE Q CG 1 +ATOM 31891 C CD1 . PHE Q 1 191 ? 19.245 81.258 27.711 1.00 204.57 ? 191 PHE Q CD1 1 +ATOM 31892 C CD2 . PHE Q 1 191 ? 19.402 78.896 28.023 1.00 253.34 ? 191 PHE Q CD2 1 +ATOM 31893 C CE1 . PHE Q 1 191 ? 19.845 81.464 28.943 1.00 178.24 ? 191 PHE Q CE1 1 +ATOM 31894 C CE2 . PHE Q 1 191 ? 19.992 79.095 29.260 1.00 221.79 ? 191 PHE Q CE2 1 +ATOM 31895 C CZ . PHE Q 1 191 ? 20.217 80.382 29.720 1.00 188.91 ? 191 PHE Q CZ 1 +ATOM 31896 N N . LEU Q 1 200 ? 13.823 82.732 30.563 1.00 290.01 ? 200 LEU Q N 1 +ATOM 31897 C CA . LEU Q 1 200 ? 13.146 81.636 29.873 1.00 290.82 ? 200 LEU Q CA 1 +ATOM 31898 C C . LEU Q 1 200 ? 14.136 80.607 29.342 1.00 273.50 ? 200 LEU Q C 1 +ATOM 31899 O O . LEU Q 1 200 ? 14.919 80.902 28.432 1.00 222.63 ? 200 LEU Q O 1 +ATOM 31900 C CB . LEU Q 1 200 ? 12.309 82.164 28.701 1.00 265.76 ? 200 LEU Q CB 1 +ATOM 31901 C CG . LEU Q 1 200 ? 11.728 81.064 27.790 1.00 212.11 ? 200 LEU Q CG 1 +ATOM 31902 C CD1 . LEU Q 1 200 ? 10.261 80.832 28.125 1.00 195.95 ? 200 LEU Q CD1 1 +ATOM 31903 C CD2 . LEU Q 1 200 ? 11.921 81.356 26.305 1.00 165.33 ? 200 LEU Q CD2 1 +ATOM 31904 N N . GLU Q 1 201 ? 14.074 79.399 29.898 1.00 238.71 ? 201 GLU Q N 1 +ATOM 31905 C CA . GLU Q 1 201 ? 14.650 78.227 29.256 1.00 200.15 ? 201 GLU Q CA 1 +ATOM 31906 C C . GLU Q 1 201 ? 13.575 77.180 29.001 1.00 166.07 ? 201 GLU Q C 1 +ATOM 31907 O O . GLU Q 1 201 ? 12.620 77.065 29.765 1.00 95.15 ? 201 GLU Q O 1 +ATOM 31908 C CB . GLU Q 1 201 ? 15.760 77.626 30.116 1.00 219.06 ? 201 GLU Q CB 1 +ATOM 31909 C CG . GLU Q 1 201 ? 16.700 76.725 29.328 1.00 227.10 ? 201 GLU Q CG 1 +ATOM 31910 C CD . GLU Q 1 201 ? 17.817 76.133 30.178 1.00 226.50 ? 201 GLU Q CD 1 +ATOM 31911 O OE1 . GLU Q 1 201 ? 18.501 76.891 30.896 1.00 226.64 ? 201 GLU Q OE1 1 +ATOM 31912 O OE2 . GLU Q 1 201 ? 18.023 74.906 30.118 1.00 205.11 ? 201 GLU Q OE2 1 +ATOM 31913 N N . GLY Q 1 202 ? 13.736 76.421 27.920 1.00 172.34 ? 202 GLY Q N 1 +ATOM 31914 C CA . GLY Q 1 202 ? 12.859 75.290 27.626 1.00 162.23 ? 202 GLY Q CA 1 +ATOM 31915 C C . GLY Q 1 202 ? 13.562 74.256 26.758 1.00 146.99 ? 202 GLY Q C 1 +ATOM 31916 O O . GLY Q 1 202 ? 14.087 74.586 25.700 1.00 109.69 ? 202 GLY Q O 1 +ATOM 31917 N N . GLU Q 1 203 ? 13.527 72.993 27.177 1.00 135.94 ? 203 GLU Q N 1 +ATOM 31918 C CA . GLU Q 1 203 ? 14.178 71.917 26.422 1.00 145.01 ? 203 GLU Q CA 1 +ATOM 31919 C C . GLU Q 1 203 ? 13.264 70.719 26.134 1.00 137.03 ? 203 GLU Q C 1 +ATOM 31920 O O . GLU Q 1 203 ? 12.521 70.259 27.005 1.00 91.40 ? 203 GLU Q O 1 +ATOM 31921 C CB . GLU Q 1 203 ? 15.442 71.445 27.155 1.00 167.01 ? 203 GLU Q CB 1 +ATOM 31922 C CG . GLU Q 1 203 ? 16.512 72.527 27.207 1.00 160.89 ? 203 GLU Q CG 1 +ATOM 31923 C CD . GLU Q 1 203 ? 17.439 72.595 26.000 1.00 163.17 ? 203 GLU Q CD 1 +ATOM 31924 O OE1 . GLU Q 1 203 ? 17.841 71.560 25.443 1.00 152.46 ? 203 GLU Q OE1 1 +ATOM 31925 O OE2 . GLU Q 1 203 ? 17.833 73.707 25.623 1.00 165.89 ? 203 GLU Q OE2 1 +ATOM 31926 N N . VAL Q 1 204 ? 13.364 70.204 24.907 1.00 166.60 ? 204 VAL Q N 1 +ATOM 31927 C CA . VAL Q 1 204 ? 12.763 68.930 24.510 1.00 184.94 ? 204 VAL Q CA 1 +ATOM 31928 C C . VAL Q 1 204 ? 13.856 67.990 23.976 1.00 202.79 ? 204 VAL Q C 1 +ATOM 31929 O O . VAL Q 1 204 ? 14.732 68.408 23.217 1.00 171.85 ? 204 VAL Q O 1 +ATOM 31930 C CB . VAL Q 1 204 ? 11.663 69.144 23.441 1.00 144.69 ? 204 VAL Q CB 1 +ATOM 31931 C CG1 . VAL Q 1 204 ? 11.284 67.836 22.746 1.00 140.73 ? 204 VAL Q CG1 1 +ATOM 31932 C CG2 . VAL Q 1 204 ? 10.439 69.782 24.079 1.00 106.81 ? 204 VAL Q CG2 1 +ATOM 31933 N N . GLY Q 1 205 ? 13.794 66.723 24.389 1.00 180.33 ? 205 GLY Q N 1 +ATOM 31934 C CA . GLY Q 1 205 ? 14.721 65.708 23.910 1.00 143.68 ? 205 GLY Q CA 1 +ATOM 31935 C C . GLY Q 1 205 ? 14.042 64.385 23.597 1.00 155.40 ? 205 GLY Q C 1 +ATOM 31936 O O . GLY Q 1 205 ? 13.014 64.051 24.188 1.00 133.86 ? 205 GLY Q O 1 +ATOM 31937 N N . TYR Q 1 206 ? 14.625 63.620 22.672 1.00 199.98 ? 206 TYR Q N 1 +ATOM 31938 C CA . TYR Q 1 206 ? 14.168 62.254 22.351 1.00 222.00 ? 206 TYR Q CA 1 +ATOM 31939 C C . TYR Q 1 206 ? 15.351 61.379 21.919 1.00 202.51 ? 206 TYR Q C 1 +ATOM 31940 O O . TYR Q 1 206 ? 16.225 61.848 21.210 1.00 145.36 ? 206 TYR Q O 1 +ATOM 31941 C CB . TYR Q 1 206 ? 13.117 62.287 21.227 1.00 209.18 ? 206 TYR Q CB 1 +ATOM 31942 C CG . TYR Q 1 206 ? 12.620 60.925 20.780 1.00 190.62 ? 206 TYR Q CG 1 +ATOM 31943 C CD1 . TYR Q 1 206 ? 11.699 60.209 21.548 1.00 152.27 ? 206 TYR Q CD1 1 +ATOM 31944 C CD2 . TYR Q 1 206 ? 13.072 60.358 19.586 1.00 185.35 ? 206 TYR Q CD2 1 +ATOM 31945 C CE1 . TYR Q 1 206 ? 11.258 58.964 21.147 1.00 148.90 ? 206 TYR Q CE1 1 +ATOM 31946 C CE2 . TYR Q 1 206 ? 12.633 59.115 19.171 1.00 180.68 ? 206 TYR Q CE2 1 +ATOM 31947 C CZ . TYR Q 1 206 ? 11.732 58.419 19.955 1.00 189.36 ? 206 TYR Q CZ 1 +ATOM 31948 O OH . TYR Q 1 206 ? 11.340 57.157 19.552 1.00 243.83 ? 206 TYR Q OH 1 +ATOM 31949 N N . THR Q 1 207 ? 15.359 60.110 22.332 1.00 178.20 ? 207 THR Q N 1 +ATOM 31950 C CA . THR Q 1 207 ? 16.417 59.169 21.932 1.00 147.68 ? 207 THR Q CA 1 +ATOM 31951 C C . THR Q 1 207 ? 15.861 57.778 21.592 1.00 146.33 ? 207 THR Q C 1 +ATOM 31952 O O . THR Q 1 207 ? 14.949 57.282 22.267 1.00 127.51 ? 207 THR Q O 1 +ATOM 31953 C CB . THR Q 1 207 ? 17.452 58.993 23.044 1.00 148.30 ? 207 THR Q CB 1 +ATOM 31954 O OG1 . THR Q 1 207 ? 16.812 58.446 24.205 1.00 142.28 ? 207 THR Q OG1 1 +ATOM 31955 C CG2 . THR Q 1 207 ? 18.082 60.319 23.410 1.00 149.23 ? 207 THR Q CG2 1 +ATOM 31956 N N . SER Q 1 208 ? 16.365 57.171 20.513 1.00 155.32 ? 208 SER Q N 1 +ATOM 31957 C CA . SER Q 1 208 ? 15.861 55.849 20.079 1.00 140.05 ? 208 SER Q CA 1 +ATOM 31958 C C . SER Q 1 208 ? 16.977 54.886 19.693 1.00 162.50 ? 208 SER Q C 1 +ATOM 31959 O O . SER Q 1 208 ? 17.839 55.216 18.862 1.00 160.13 ? 208 SER Q O 1 +ATOM 31960 C CB . SER Q 1 208 ? 14.893 55.978 18.904 1.00 135.35 ? 208 SER Q CB 1 +ATOM 31961 O OG . SER Q 1 208 ? 14.515 54.700 18.410 1.00 90.77 ? 208 SER Q OG 1 +ATOM 31962 N N . ASN Q 1 209 ? 16.940 53.700 20.295 1.00 154.48 ? 209 ASN Q N 1 +ATOM 31963 C CA . ASN Q 1 209 ? 17.880 52.634 19.980 1.00 151.08 ? 209 ASN Q CA 1 +ATOM 31964 C C . ASN Q 1 209 ? 17.159 51.460 19.367 1.00 155.12 ? 209 ASN Q C 1 +ATOM 31965 O O . ASN Q 1 209 ? 16.098 51.078 19.839 1.00 122.80 ? 209 ASN Q O 1 +ATOM 31966 C CB . ASN Q 1 209 ? 18.574 52.146 21.240 1.00 140.90 ? 209 ASN Q CB 1 +ATOM 31967 C CG . ASN Q 1 209 ? 19.536 53.164 21.794 1.00 145.18 ? 209 ASN Q CG 1 +ATOM 31968 O OD1 . ASN Q 1 209 ? 20.686 53.246 21.368 1.00 159.53 ? 209 ASN Q OD1 1 +ATOM 31969 N ND2 . ASN Q 1 209 ? 19.094 53.896 22.799 1.00 156.81 ? 209 ASN Q ND2 1 +ATOM 31970 N N . GLU Q 1 210 ? 17.750 50.872 18.326 1.00 162.94 ? 210 GLU Q N 1 +ATOM 31971 C CA . GLU Q 1 210 ? 17.276 49.586 17.818 1.00 114.92 ? 210 GLU Q CA 1 +ATOM 31972 C C . GLU Q 1 210 ? 17.587 48.547 18.870 1.00 109.42 ? 210 GLU Q C 1 +ATOM 31973 O O . GLU Q 1 210 ? 18.634 48.605 19.530 1.00 110.79 ? 210 GLU Q O 1 +ATOM 31974 C CB . GLU Q 1 210 ? 17.968 49.215 16.506 1.00 115.23 ? 210 GLU Q CB 1 +ATOM 31975 C CG . GLU Q 1 210 ? 17.054 48.645 15.433 1.00 111.56 ? 210 GLU Q CG 1 +ATOM 31976 C CD . GLU Q 1 210 ? 17.686 48.688 14.038 1.00 141.76 ? 210 GLU Q CD 1 +ATOM 31977 O OE1 . GLU Q 1 210 ? 18.578 49.551 13.752 1.00 110.04 ? 210 GLU Q OE1 1 +ATOM 31978 O OE2 . GLU Q 1 210 ? 17.313 47.826 13.209 1.00 176.09 ? 210 GLU Q OE2 1 +ATOM 31979 N N . PRO Q 1 211 ? 16.680 47.599 19.051 1.00 115.35 ? 211 PRO Q N 1 +ATOM 31980 C CA . PRO Q 1 211 ? 16.999 46.494 19.927 1.00 140.22 ? 211 PRO Q CA 1 +ATOM 31981 C C . PRO Q 1 211 ? 18.021 45.533 19.274 1.00 167.68 ? 211 PRO Q C 1 +ATOM 31982 O O . PRO Q 1 211 ? 17.794 45.046 18.163 1.00 155.32 ? 211 PRO Q O 1 +ATOM 31983 C CB . PRO Q 1 211 ? 15.642 45.811 20.138 1.00 132.09 ? 211 PRO Q CB 1 +ATOM 31984 C CG . PRO Q 1 211 ? 14.623 46.812 19.744 1.00 133.60 ? 211 PRO Q CG 1 +ATOM 31985 C CD . PRO Q 1 211 ? 15.271 47.595 18.647 1.00 133.93 ? 211 PRO Q CD 1 +ATOM 31986 N N . VAL Q 1 212 ? 19.131 45.274 19.973 1.00 136.04 ? 212 VAL Q N 1 +ATOM 31987 C CA . VAL Q 1 212 ? 20.174 44.343 19.505 1.00 81.13 ? 212 VAL Q CA 1 +ATOM 31988 C C . VAL Q 1 212 ? 19.606 42.935 19.433 1.00 57.36 ? 212 VAL Q C 1 +ATOM 31989 O O . VAL Q 1 212 ? 19.804 42.209 18.467 1.00 35.12 ? 212 VAL Q O 1 +ATOM 31990 C CB . VAL Q 1 212 ? 21.366 44.314 20.469 1.00 115.69 ? 212 VAL Q CB 1 +ATOM 31991 C CG1 . VAL Q 1 212 ? 22.480 43.453 19.900 1.00 114.84 ? 212 VAL Q CG1 1 +ATOM 31992 C CG2 . VAL Q 1 212 ? 21.873 45.726 20.773 1.00 165.31 ? 212 VAL Q CG2 1 +ATOM 31993 N N . MET Q 1 213 ? 18.832 42.606 20.453 1.00 55.01 ? 213 MET Q N 1 +ATOM 31994 C CA . MET Q 1 213 ? 17.856 41.518 20.431 1.00 88.93 ? 213 MET Q CA 1 +ATOM 31995 C C . MET Q 1 213 ? 17.192 41.251 19.054 1.00 113.32 ? 213 MET Q C 1 +ATOM 31996 O O . MET Q 1 213 ? 17.173 40.117 18.543 1.00 150.65 ? 213 MET Q O 1 +ATOM 31997 C CB . MET Q 1 213 ? 16.784 41.899 21.465 1.00 91.96 ? 213 MET Q CB 1 +ATOM 31998 C CG . MET Q 1 213 ? 15.714 40.884 21.776 1.00 92.79 ? 213 MET Q CG 1 +ATOM 31999 S SD . MET Q 1 213 ? 14.653 41.609 23.014 1.00 125.31 ? 213 MET Q SD 1 +ATOM 32000 C CE . MET Q 1 213 ? 13.221 41.902 22.016 1.00 149.06 ? 213 MET Q CE 1 +ATOM 32001 N N . LEU Q 1 214 ? 16.651 42.312 18.464 1.00 138.00 ? 214 LEU Q N 1 +ATOM 32002 C CA . LEU Q 1 214 ? 15.734 42.216 17.323 1.00 128.90 ? 214 LEU Q CA 1 +ATOM 32003 C C . LEU Q 1 214 ? 16.524 42.169 16.026 1.00 118.68 ? 214 LEU Q C 1 +ATOM 32004 O O . LEU Q 1 214 ? 16.130 41.492 15.074 1.00 120.91 ? 214 LEU Q O 1 +ATOM 32005 C CB . LEU Q 1 214 ? 14.794 43.425 17.297 1.00 119.35 ? 214 LEU Q CB 1 +ATOM 32006 C CG . LEU Q 1 214 ? 13.310 43.184 16.982 1.00 138.32 ? 214 LEU Q CG 1 +ATOM 32007 C CD1 . LEU Q 1 214 ? 12.619 42.232 17.984 1.00 149.90 ? 214 LEU Q CD1 1 +ATOM 32008 C CD2 . LEU Q 1 214 ? 12.603 44.539 16.934 1.00 139.23 ? 214 LEU Q CD2 1 +ATOM 32009 N N . CYS Q 1 215 ? 17.702 42.768 16.056 1.00 120.44 ? 215 CYS Q N 1 +ATOM 32010 C CA . CYS Q 1 215 ? 18.643 42.655 14.949 1.00 141.36 ? 215 CYS Q CA 1 +ATOM 32011 C C . CYS Q 1 215 ? 19.273 41.259 14.844 1.00 124.41 ? 215 CYS Q C 1 +ATOM 32012 O O . CYS Q 1 215 ? 19.445 40.701 13.733 1.00 114.39 ? 215 CYS Q O 1 +ATOM 32013 C CB . CYS Q 1 215 ? 19.760 43.665 15.139 1.00 186.60 ? 215 CYS Q CB 1 +ATOM 32014 S SG . CYS Q 1 215 ? 19.176 45.362 15.136 1.00 245.85 ? 215 CYS Q SG 1 +ATOM 32015 N N . LEU Q 1 216 ? 19.647 40.705 16.001 1.00 89.22 ? 216 LEU Q N 1 +ATOM 32016 C CA . LEU Q 1 216 ? 20.110 39.331 16.060 1.00 79.63 ? 216 LEU Q CA 1 +ATOM 32017 C C . LEU Q 1 216 ? 19.065 38.375 15.445 1.00 97.22 ? 216 LEU Q C 1 +ATOM 32018 O O . LEU Q 1 216 ? 19.375 37.567 14.566 1.00 115.70 ? 216 LEU Q O 1 +ATOM 32019 C CB . LEU Q 1 216 ? 20.395 38.929 17.493 1.00 61.97 ? 216 LEU Q CB 1 +ATOM 32020 C CG . LEU Q 1 216 ? 20.866 37.489 17.656 1.00 73.42 ? 216 LEU Q CG 1 +ATOM 32021 C CD1 . LEU Q 1 216 ? 22.131 37.174 16.863 1.00 83.30 ? 216 LEU Q CD1 1 +ATOM 32022 C CD2 . LEU Q 1 216 ? 21.142 37.199 19.123 1.00 101.80 ? 216 LEU Q CD2 1 +ATOM 32023 N N . MET Q 1 217 ? 17.809 38.551 15.836 1.00 92.16 ? 217 MET Q N 1 +ATOM 32024 C CA . MET Q 1 217 ? 16.738 37.692 15.355 1.00 68.98 ? 217 MET Q CA 1 +ATOM 32025 C C . MET Q 1 217 ? 16.595 37.796 13.862 1.00 47.25 ? 217 MET Q C 1 +ATOM 32026 O O . MET Q 1 217 ? 16.521 36.797 13.158 1.00 40.18 ? 217 MET Q O 1 +ATOM 32027 C CB . MET Q 1 217 ? 15.411 38.023 16.071 1.00 77.48 ? 217 MET Q CB 1 +ATOM 32028 C CG . MET Q 1 217 ? 14.637 36.788 16.525 1.00 95.04 ? 217 MET Q CG 1 +ATOM 32029 S SD . MET Q 1 217 ? 13.969 35.849 15.142 1.00 123.14 ? 217 MET Q SD 1 +ATOM 32030 C CE . MET Q 1 217 ? 13.386 34.341 15.929 1.00 136.07 ? 217 MET Q CE 1 +ATOM 32031 N N . SER Q 1 218 ? 16.602 39.015 13.378 1.00 59.19 ? 218 SER Q N 1 +ATOM 32032 C CA . SER Q 1 218 ? 16.447 39.284 11.934 1.00 100.65 ? 218 SER Q CA 1 +ATOM 32033 C C . SER Q 1 218 ? 17.534 38.593 11.135 1.00 80.42 ? 218 SER Q C 1 +ATOM 32034 O O . SER Q 1 218 ? 17.256 37.906 10.145 1.00 103.43 ? 218 SER Q O 1 +ATOM 32035 C CB . SER Q 1 218 ? 16.492 40.808 11.664 1.00 116.33 ? 218 SER Q CB 1 +ATOM 32036 O OG . SER Q 1 218 ? 16.158 41.109 10.301 1.00 65.05 ? 218 SER Q OG 1 +ATOM 32037 N N . ALA Q 1 219 ? 18.764 38.761 11.591 1.00 63.01 ? 219 ALA Q N 1 +ATOM 32038 C CA . ALA Q 1 219 ? 19.907 38.254 10.859 1.00 73.16 ? 219 ALA Q CA 1 +ATOM 32039 C C . ALA Q 1 219 ? 19.874 36.692 10.820 1.00 67.72 ? 219 ALA Q C 1 +ATOM 32040 O O . ALA Q 1 219 ? 20.310 36.071 9.851 1.00 54.24 ? 219 ALA Q O 1 +ATOM 32041 C CB . ALA Q 1 219 ? 21.207 38.798 11.476 1.00 68.88 ? 219 ALA Q CB 1 +ATOM 32042 N N . ILE Q 1 220 ? 19.361 36.079 11.873 1.00 61.47 ? 220 ILE Q N 1 +ATOM 32043 C CA . ILE Q 1 220 ? 19.333 34.627 11.949 1.00 77.67 ? 220 ILE Q CA 1 +ATOM 32044 C C . ILE Q 1 220 ? 18.307 34.096 10.970 1.00 75.52 ? 220 ILE Q C 1 +ATOM 32045 O O . ILE Q 1 220 ? 18.529 33.101 10.296 1.00 71.79 ? 220 ILE Q O 1 +ATOM 32046 C CB . ILE Q 1 220 ? 19.006 34.141 13.393 1.00 121.97 ? 220 ILE Q CB 1 +ATOM 32047 C CG1 . ILE Q 1 220 ? 20.204 34.396 14.328 1.00 121.66 ? 220 ILE Q CG1 1 +ATOM 32048 C CG2 . ILE Q 1 220 ? 18.633 32.657 13.399 1.00 125.72 ? 220 ILE Q CG2 1 +ATOM 32049 C CD1 . ILE Q 1 220 ? 19.877 34.339 15.812 1.00 79.24 ? 220 ILE Q CD1 1 +ATOM 32050 N N . GLU Q 1 221 ? 17.176 34.779 10.881 1.00 103.75 ? 221 GLU Q N 1 +ATOM 32051 C CA . GLU Q 1 221 ? 16.145 34.424 9.900 1.00 116.89 ? 221 GLU Q CA 1 +ATOM 32052 C C . GLU Q 1 221 ? 16.738 34.446 8.492 1.00 106.74 ? 221 GLU Q C 1 +ATOM 32053 O O . GLU Q 1 221 ? 16.590 33.489 7.722 1.00 100.85 ? 221 GLU Q O 1 +ATOM 32054 C CB . GLU Q 1 221 ? 14.951 35.403 9.997 1.00 131.29 ? 221 GLU Q CB 1 +ATOM 32055 C CG . GLU Q 1 221 ? 14.072 35.173 11.223 1.00 147.71 ? 221 GLU Q CG 1 +ATOM 32056 C CD . GLU Q 1 221 ? 13.167 36.343 11.562 1.00 141.10 ? 221 GLU Q CD 1 +ATOM 32057 O OE1 . GLU Q 1 221 ? 13.577 37.526 11.377 1.00 145.72 ? 221 GLU Q OE1 1 +ATOM 32058 O OE2 . GLU Q 1 221 ? 12.041 36.068 12.027 1.00 114.86 ? 221 GLU Q OE2 1 +ATOM 32059 N N . THR Q 1 222 ? 17.373 35.573 8.159 1.00 92.23 ? 222 THR Q N 1 +ATOM 32060 C CA . THR Q 1 222 ? 18.032 35.778 6.868 1.00 77.89 ? 222 THR Q CA 1 +ATOM 32061 C C . THR Q 1 222 ? 18.980 34.626 6.559 1.00 76.70 ? 222 THR Q C 1 +ATOM 32062 O O . THR Q 1 222 ? 18.962 34.074 5.458 1.00 68.45 ? 222 THR Q O 1 +ATOM 32063 C CB . THR Q 1 222 ? 18.841 37.095 6.880 1.00 80.83 ? 222 THR Q CB 1 +ATOM 32064 O OG1 . THR Q 1 222 ? 17.941 38.219 6.862 1.00 76.38 ? 222 THR Q OG1 1 +ATOM 32065 C CG2 . THR Q 1 222 ? 19.838 37.159 5.705 1.00 78.47 ? 222 THR Q CG2 1 +ATOM 32066 N N . GLY Q 1 223 ? 19.803 34.277 7.541 1.00 95.61 ? 223 GLY Q N 1 +ATOM 32067 C CA . GLY Q 1 223 ? 20.713 33.136 7.423 1.00 121.68 ? 223 GLY Q CA 1 +ATOM 32068 C C . GLY Q 1 223 ? 19.999 31.829 7.117 1.00 124.93 ? 223 GLY Q C 1 +ATOM 32069 O O . GLY Q 1 223 ? 20.469 31.037 6.301 1.00 114.87 ? 223 GLY Q O 1 +ATOM 32070 N N . VAL Q 1 224 ? 18.848 31.607 7.758 1.00 135.28 ? 224 VAL Q N 1 +ATOM 32071 C CA . VAL Q 1 224 ? 18.077 30.394 7.523 1.00 124.25 ? 224 VAL Q CA 1 +ATOM 32072 C C . VAL Q 1 224 ? 17.608 30.345 6.063 1.00 136.01 ? 224 VAL Q C 1 +ATOM 32073 O O . VAL Q 1 224 ? 17.670 29.304 5.408 1.00 116.95 ? 224 VAL Q O 1 +ATOM 32074 C CB . VAL Q 1 224 ? 16.856 30.307 8.450 1.00 114.24 ? 224 VAL Q CB 1 +ATOM 32075 C CG1 . VAL Q 1 224 ? 15.989 29.116 8.045 1.00 137.76 ? 224 VAL Q CG1 1 +ATOM 32076 C CG2 . VAL Q 1 224 ? 17.297 30.187 9.888 1.00 93.15 ? 224 VAL Q CG2 1 +ATOM 32077 N N . ILE Q 1 225 ? 17.143 31.483 5.545 1.00 119.75 ? 225 ILE Q N 1 +ATOM 32078 C CA . ILE Q 1 225 ? 16.727 31.553 4.150 1.00 102.44 ? 225 ILE Q CA 1 +ATOM 32079 C C . ILE Q 1 225 ? 17.884 31.200 3.217 1.00 99.18 ? 225 ILE Q C 1 +ATOM 32080 O O . ILE Q 1 225 ? 17.726 30.329 2.363 1.00 90.58 ? 225 ILE Q O 1 +ATOM 32081 C CB . ILE Q 1 225 ? 16.156 32.930 3.781 1.00 99.74 ? 225 ILE Q CB 1 +ATOM 32082 C CG1 . ILE Q 1 225 ? 14.825 33.167 4.505 1.00 88.51 ? 225 ILE Q CG1 1 +ATOM 32083 C CG2 . ILE Q 1 225 ? 15.918 33.018 2.279 1.00 122.09 ? 225 ILE Q CG2 1 +ATOM 32084 C CD1 . ILE Q 1 225 ? 14.409 34.623 4.543 1.00 110.05 ? 225 ILE Q CD1 1 +ATOM 32085 N N . PHE Q 1 226 ? 19.031 31.867 3.386 1.00 106.13 ? 226 PHE Q N 1 +ATOM 32086 C CA . PHE Q 1 226 ? 20.220 31.596 2.562 1.00 119.15 ? 226 PHE Q CA 1 +ATOM 32087 C C . PHE Q 1 226 ? 20.617 30.131 2.634 1.00 117.78 ? 226 PHE Q C 1 +ATOM 32088 O O . PHE Q 1 226 ? 21.107 29.569 1.656 1.00 122.01 ? 226 PHE Q O 1 +ATOM 32089 C CB . PHE Q 1 226 ? 21.408 32.470 2.980 1.00 127.36 ? 226 PHE Q CB 1 +ATOM 32090 C CG . PHE Q 1 226 ? 21.356 33.888 2.438 1.00 146.98 ? 226 PHE Q CG 1 +ATOM 32091 C CD1 . PHE Q 1 226 ? 21.326 34.129 1.067 1.00 143.20 ? 226 PHE Q CD1 1 +ATOM 32092 C CD2 . PHE Q 1 226 ? 21.394 34.985 3.300 1.00 129.63 ? 226 PHE Q CD2 1 +ATOM 32093 C CE1 . PHE Q 1 226 ? 21.307 35.427 0.570 1.00 120.45 ? 226 PHE Q CE1 1 +ATOM 32094 C CE2 . PHE Q 1 226 ? 21.393 36.281 2.809 1.00 97.13 ? 226 PHE Q CE2 1 +ATOM 32095 C CZ . PHE Q 1 226 ? 21.343 36.503 1.445 1.00 107.09 ? 226 PHE Q CZ 1 +ATOM 32096 N N . LEU Q 1 227 ? 20.362 29.492 3.778 1.00 145.93 ? 227 LEU Q N 1 +ATOM 32097 C CA . LEU Q 1 227 ? 20.656 28.045 3.938 1.00 141.74 ? 227 LEU Q CA 1 +ATOM 32098 C C . LEU Q 1 227 ? 19.738 27.219 3.102 1.00 127.51 ? 227 LEU Q C 1 +ATOM 32099 O O . LEU Q 1 227 ? 20.188 26.285 2.446 1.00 152.42 ? 227 LEU Q O 1 +ATOM 32100 C CB . LEU Q 1 227 ? 20.459 27.549 5.370 1.00 129.84 ? 227 LEU Q CB 1 +ATOM 32101 C CG . LEU Q 1 227 ? 21.680 27.016 6.125 1.00 124.98 ? 227 LEU Q CG 1 +ATOM 32102 C CD1 . LEU Q 1 227 ? 22.890 27.720 5.618 1.00 104.34 ? 227 LEU Q CD1 1 +ATOM 32103 C CD2 . LEU Q 1 227 ? 21.666 27.074 7.660 1.00 150.98 ? 227 LEU Q CD2 1 +ATOM 32104 N N . ILE Q 1 228 ? 18.449 27.551 3.142 1.00 96.19 ? 228 ILE Q N 1 +ATOM 32105 C CA . ILE Q 1 228 ? 17.449 26.786 2.401 1.00 98.85 ? 228 ILE Q CA 1 +ATOM 32106 C C . ILE Q 1 228 ? 17.681 26.930 0.903 1.00 102.44 ? 228 ILE Q C 1 +ATOM 32107 O O . ILE Q 1 228 ? 17.742 25.936 0.177 1.00 91.63 ? 228 ILE Q O 1 +ATOM 32108 C CB . ILE Q 1 228 ? 16.008 27.232 2.701 1.00 95.82 ? 228 ILE Q CB 1 +ATOM 32109 C CG1 . ILE Q 1 228 ? 15.648 26.979 4.167 1.00 98.08 ? 228 ILE Q CG1 1 +ATOM 32110 C CG2 . ILE Q 1 228 ? 15.039 26.466 1.825 1.00 90.65 ? 228 ILE Q CG2 1 +ATOM 32111 C CD1 . ILE Q 1 228 ? 14.403 27.706 4.653 1.00 75.48 ? 228 ILE Q CD1 1 +ATOM 32112 N N . ASN Q 1 229 ? 17.898 28.165 0.462 1.00 114.26 ? 229 ASN Q N 1 +ATOM 32113 C CA . ASN Q 1 229 ? 18.172 28.444 -0.949 1.00 128.41 ? 229 ASN Q CA 1 +ATOM 32114 C C . ASN Q 1 229 ? 19.436 27.740 -1.443 1.00 111.14 ? 229 ASN Q C 1 +ATOM 32115 O O . ASN Q 1 229 ? 19.429 27.096 -2.489 1.00 136.99 ? 229 ASN Q O 1 +ATOM 32116 C CB . ASN Q 1 229 ? 18.306 29.954 -1.169 1.00 138.11 ? 229 ASN Q CB 1 +ATOM 32117 C CG . ASN Q 1 229 ? 18.177 30.347 -2.625 1.00 140.82 ? 229 ASN Q CG 1 +ATOM 32118 O OD1 . ASN Q 1 229 ? 17.566 29.632 -3.427 1.00 139.60 ? 229 ASN Q OD1 1 +ATOM 32119 N ND2 . ASN Q 1 229 ? 18.723 31.505 -2.965 1.00 152.06 ? 229 ASN Q ND2 1 +ATOM 32120 N N . ASP Q 1 230 ? 20.492 27.808 -0.639 1.00 119.73 ? 230 ASP Q N 1 +ATOM 32121 C CA . ASP Q 1 230 ? 21.739 27.117 -0.929 1.00 121.66 ? 230 ASP Q CA 1 +ATOM 32122 C C . ASP Q 1 230 ? 21.512 25.604 -1.030 1.00 137.70 ? 230 ASP Q C 1 +ATOM 32123 O O . ASP Q 1 230 ? 22.056 24.942 -1.910 1.00 145.03 ? 230 ASP Q O 1 +ATOM 32124 C CB . ASP Q 1 230 ? 22.778 27.427 0.155 1.00 136.23 ? 230 ASP Q CB 1 +ATOM 32125 C CG . ASP Q 1 230 ? 24.148 26.891 -0.184 1.00 153.73 ? 230 ASP Q CG 1 +ATOM 32126 O OD1 . ASP Q 1 230 ? 24.770 27.449 -1.111 1.00 95.98 ? 230 ASP Q OD1 1 +ATOM 32127 O OD2 . ASP Q 1 230 ? 24.574 25.877 0.461 1.00 246.30 ? 230 ASP Q OD2 1 +ATOM 32128 N N . GLY Q 1 231 ? 20.705 25.053 -0.124 1.00 151.25 ? 231 GLY Q N 1 +ATOM 32129 C CA . GLY Q 1 231 ? 20.420 23.617 -0.122 1.00 135.58 ? 231 GLY Q CA 1 +ATOM 32130 C C . GLY Q 1 231 ? 19.606 23.195 -1.332 1.00 113.97 ? 231 GLY Q C 1 +ATOM 32131 O O . GLY Q 1 231 ? 19.788 22.090 -1.863 1.00 127.35 ? 231 GLY Q O 1 +ATOM 32132 N N . ILE Q 1 232 ? 18.699 24.071 -1.760 1.00 101.12 ? 232 ILE Q N 1 +ATOM 32133 C CA . ILE Q 1 232 ? 17.930 23.841 -2.985 1.00 114.72 ? 232 ILE Q CA 1 +ATOM 32134 C C . ILE Q 1 232 ? 18.853 23.723 -4.192 1.00 114.78 ? 232 ILE Q C 1 +ATOM 32135 O O . ILE Q 1 232 ? 18.765 22.763 -4.950 1.00 116.95 ? 232 ILE Q O 1 +ATOM 32136 C CB . ILE Q 1 232 ? 16.901 24.969 -3.228 1.00 126.48 ? 232 ILE Q CB 1 +ATOM 32137 C CG1 . ILE Q 1 232 ? 15.747 24.844 -2.218 1.00 141.13 ? 232 ILE Q CG1 1 +ATOM 32138 C CG2 . ILE Q 1 232 ? 16.369 24.933 -4.664 1.00 128.08 ? 232 ILE Q CG2 1 +ATOM 32139 C CD1 . ILE Q 1 232 ? 14.908 26.096 -2.074 1.00 125.10 ? 232 ILE Q CD1 1 +ATOM 32140 N N . ASP Q 1 233 ? 19.745 24.699 -4.345 1.00 145.20 ? 233 ASP Q N 1 +ATOM 32141 C CA . ASP Q 1 233 ? 20.743 24.692 -5.416 1.00 140.06 ? 233 ASP Q CA 1 +ATOM 32142 C C . ASP Q 1 233 ? 21.565 23.406 -5.383 1.00 118.88 ? 233 ASP Q C 1 +ATOM 32143 O O . ASP Q 1 233 ? 21.759 22.764 -6.413 1.00 137.74 ? 233 ASP Q O 1 +ATOM 32144 C CB . ASP Q 1 233 ? 21.680 25.912 -5.303 1.00 164.00 ? 233 ASP Q CB 1 +ATOM 32145 C CG . ASP Q 1 233 ? 20.958 27.245 -5.523 1.00 165.92 ? 233 ASP Q CG 1 +ATOM 32146 O OD1 . ASP Q 1 233 ? 19.710 27.257 -5.572 1.00 171.44 ? 233 ASP Q OD1 1 +ATOM 32147 O OD2 . ASP Q 1 233 ? 21.648 28.284 -5.622 1.00 131.45 ? 233 ASP Q OD2 1 +ATOM 32148 N N . ARG Q 1 234 ? 22.062 23.039 -4.205 1.00 131.62 ? 234 ARG Q N 1 +ATOM 32149 C CA . ARG Q 1 234 ? 23.028 21.934 -4.085 1.00 159.98 ? 234 ARG Q CA 1 +ATOM 32150 C C . ARG Q 1 234 ? 22.381 20.558 -4.027 1.00 138.21 ? 234 ARG Q C 1 +ATOM 32151 O O . ARG Q 1 234 ? 23.076 19.547 -3.954 1.00 114.40 ? 234 ARG Q O 1 +ATOM 32152 C CB . ARG Q 1 234 ? 23.919 22.142 -2.859 1.00 182.29 ? 234 ARG Q CB 1 +ATOM 32153 C CG . ARG Q 1 234 ? 24.936 23.245 -3.074 1.00 192.05 ? 234 ARG Q CG 1 +ATOM 32154 C CD . ARG Q 1 234 ? 25.460 23.826 -1.781 1.00 148.86 ? 234 ARG Q CD 1 +ATOM 32155 N NE . ARG Q 1 234 ? 26.376 24.916 -2.105 1.00 125.33 ? 234 ARG Q NE 1 +ATOM 32156 C CZ . ARG Q 1 234 ? 27.649 24.961 -1.736 1.00 135.37 ? 234 ARG Q CZ 1 +ATOM 32157 N NH1 . ARG Q 1 234 ? 28.140 24.023 -0.930 1.00 133.08 ? 234 ARG Q NH1 1 +ATOM 32158 N NH2 . ARG Q 1 234 ? 28.411 25.979 -2.116 1.00 136.07 ? 234 ARG Q NH2 1 +ATOM 32159 N N . GLY Q 1 235 ? 21.052 20.525 -4.080 1.00 137.30 ? 235 GLY Q N 1 +ATOM 32160 C CA . GLY Q 1 235 ? 20.317 19.264 -4.126 1.00 119.96 ? 235 GLY Q CA 1 +ATOM 32161 C C . GLY Q 1 235 ? 20.252 18.558 -2.785 1.00 128.30 ? 235 GLY Q C 1 +ATOM 32162 O O . GLY Q 1 235 ? 20.251 17.326 -2.734 1.00 131.26 ? 235 GLY Q O 1 +ATOM 32163 N N . LEU Q 1 236 ? 20.234 19.323 -1.692 1.00 148.46 ? 236 LEU Q N 1 +ATOM 32164 C CA . LEU Q 1 236 ? 19.939 18.738 -0.372 1.00 147.04 ? 236 LEU Q CA 1 +ATOM 32165 C C . LEU Q 1 236 ? 18.451 18.411 -0.278 1.00 117.30 ? 236 LEU Q C 1 +ATOM 32166 O O . LEU Q 1 236 ? 18.068 17.303 0.095 1.00 103.64 ? 236 LEU Q O 1 +ATOM 32167 C CB . LEU Q 1 236 ? 20.320 19.686 0.776 1.00 174.96 ? 236 LEU Q CB 1 +ATOM 32168 C CG . LEU Q 1 236 ? 21.784 19.697 1.250 1.00 168.30 ? 236 LEU Q CG 1 +ATOM 32169 C CD1 . LEU Q 1 236 ? 22.645 20.512 0.298 1.00 164.44 ? 236 LEU Q CD1 1 +ATOM 32170 C CD2 . LEU Q 1 236 ? 21.878 20.259 2.660 1.00 151.37 ? 236 LEU Q CD2 1 +ATOM 32171 N N . TRP Q 1 237 ? 17.622 19.371 -0.666 1.00 111.85 ? 237 TRP Q N 1 +ATOM 32172 C CA . TRP Q 1 237 ? 16.171 19.205 -0.623 1.00 134.44 ? 237 TRP Q CA 1 +ATOM 32173 C C . TRP Q 1 237 ? 15.517 19.826 -1.870 1.00 166.03 ? 237 TRP Q C 1 +ATOM 32174 O O . TRP Q 1 237 ? 16.167 20.571 -2.620 1.00 138.35 ? 237 TRP Q O 1 +ATOM 32175 C CB . TRP Q 1 237 ? 15.619 19.833 0.651 1.00 123.00 ? 237 TRP Q CB 1 +ATOM 32176 C CG . TRP Q 1 237 ? 16.394 21.036 1.083 1.00 136.78 ? 237 TRP Q CG 1 +ATOM 32177 C CD1 . TRP Q 1 237 ? 16.470 22.231 0.434 1.00 153.57 ? 237 TRP Q CD1 1 +ATOM 32178 C CD2 . TRP Q 1 237 ? 17.217 21.162 2.249 1.00 147.30 ? 237 TRP Q CD2 1 +ATOM 32179 N NE1 . TRP Q 1 237 ? 17.288 23.093 1.121 1.00 154.64 ? 237 TRP Q NE1 1 +ATOM 32180 C CE2 . TRP Q 1 237 ? 17.742 22.469 2.251 1.00 150.51 ? 237 TRP Q CE2 1 +ATOM 32181 C CE3 . TRP Q 1 237 ? 17.545 20.307 3.300 1.00 166.21 ? 237 TRP Q CE3 1 +ATOM 32182 C CZ2 . TRP Q 1 237 ? 18.596 22.935 3.253 1.00 137.00 ? 237 TRP Q CZ2 1 +ATOM 32183 C CZ3 . TRP Q 1 237 ? 18.384 20.780 4.303 1.00 160.45 ? 237 TRP Q CZ3 1 +ATOM 32184 C CH2 . TRP Q 1 237 ? 18.898 22.083 4.269 1.00 136.49 ? 237 TRP Q CH2 1 +ATOM 32185 N N . ASP Q 1 238 ? 14.248 19.489 -2.104 1.00 177.80 ? 238 ASP Q N 1 +ATOM 32186 C CA . ASP Q 1 238 ? 13.561 19.863 -3.344 1.00 175.21 ? 238 ASP Q CA 1 +ATOM 32187 C C . ASP Q 1 238 ? 12.215 20.537 -3.092 1.00 157.51 ? 238 ASP Q C 1 +ATOM 32188 O O . ASP Q 1 238 ? 11.504 20.198 -2.139 1.00 119.74 ? 238 ASP Q O 1 +ATOM 32189 C CB . ASP Q 1 238 ? 13.359 18.644 -4.255 1.00 172.74 ? 238 ASP Q CB 1 +ATOM 32190 C CG . ASP Q 1 238 ? 14.660 17.932 -4.590 1.00 155.26 ? 238 ASP Q CG 1 +ATOM 32191 O OD1 . ASP Q 1 238 ? 15.136 17.161 -3.734 1.00 145.56 ? 238 ASP Q OD1 1 +ATOM 32192 O OD2 . ASP Q 1 238 ? 15.206 18.145 -5.696 1.00 137.24 ? 238 ASP Q OD2 1 +ATOM 32193 N N . LEU Q 1 239 ? 11.852 21.449 -3.996 1.00 143.01 ? 239 LEU Q N 1 +ATOM 32194 C CA . LEU Q 1 239 ? 10.596 22.176 -3.905 1.00 145.01 ? 239 LEU Q CA 1 +ATOM 32195 C C . LEU Q 1 239 ? 9.426 21.299 -4.341 1.00 155.59 ? 239 LEU Q C 1 +ATOM 32196 O O . LEU Q 1 239 ? 9.554 20.466 -5.239 1.00 141.99 ? 239 LEU Q O 1 +ATOM 32197 C CB . LEU Q 1 239 ? 10.632 23.429 -4.783 1.00 171.29 ? 239 LEU Q CB 1 +ATOM 32198 C CG . LEU Q 1 239 ? 11.410 24.656 -4.313 1.00 177.43 ? 239 LEU Q CG 1 +ATOM 32199 C CD1 . LEU Q 1 239 ? 11.219 25.815 -5.282 1.00 191.59 ? 239 LEU Q CD1 1 +ATOM 32200 C CD2 . LEU Q 1 239 ? 10.974 25.066 -2.923 1.00 173.72 ? 239 LEU Q CD2 1 +ATOM 32201 N N . GLN Q 1 240 ? 8.284 21.495 -3.687 1.00 159.50 ? 240 GLN Q N 1 +ATOM 32202 C CA . GLN Q 1 240 ? 7.026 20.876 -4.118 1.00 131.94 ? 240 GLN Q CA 1 +ATOM 32203 C C . GLN Q 1 240 ? 6.732 21.227 -5.570 1.00 139.22 ? 240 GLN Q C 1 +ATOM 32204 O O . GLN Q 1 240 ? 6.592 20.344 -6.413 1.00 166.26 ? 240 GLN Q O 1 +ATOM 32205 C CB . GLN Q 1 240 ? 5.869 21.349 -3.223 1.00 126.71 ? 240 GLN Q CB 1 +ATOM 32206 C CG . GLN Q 1 240 ? 4.557 20.617 -3.470 1.00 108.97 ? 240 GLN Q CG 1 +ATOM 32207 C CD . GLN Q 1 240 ? 4.643 19.144 -3.102 1.00 134.69 ? 240 GLN Q CD 1 +ATOM 32208 O OE1 . GLN Q 1 240 ? 4.557 18.780 -1.921 1.00 161.63 ? 240 GLN Q OE1 1 +ATOM 32209 N NE2 . GLN Q 1 240 ? 4.881 18.294 -4.097 1.00 145.45 ? 240 GLN Q NE2 1 +ATOM 32210 N N . ASN Q 1 241 ? 6.680 22.526 -5.845 1.00 136.34 ? 241 ASN Q N 1 +ATOM 32211 C CA . ASN Q 1 241 ? 6.453 23.037 -7.184 1.00 120.81 ? 241 ASN Q CA 1 +ATOM 32212 C C . ASN Q 1 241 ? 7.737 23.552 -7.801 1.00 141.67 ? 241 ASN Q C 1 +ATOM 32213 O O . ASN Q 1 241 ? 8.272 24.602 -7.387 1.00 170.58 ? 241 ASN Q O 1 +ATOM 32214 C CB . ASN Q 1 241 ? 5.452 24.173 -7.125 1.00 111.66 ? 241 ASN Q CB 1 +ATOM 32215 C CG . ASN Q 1 241 ? 4.072 23.734 -7.524 1.00 121.36 ? 241 ASN Q CG 1 +ATOM 32216 O OD1 . ASN Q 1 241 ? 3.638 23.998 -8.646 1.00 145.68 ? 241 ASN Q OD1 1 +ATOM 32217 N ND2 . ASN Q 1 241 ? 3.370 23.056 -6.622 1.00 129.32 ? 241 ASN Q ND2 1 +ATOM 32218 N N . LYS Q 1 242 ? 8.223 22.840 -8.814 1.00 131.62 ? 242 LYS Q N 1 +ATOM 32219 C CA . LYS Q 1 242 ? 9.459 23.241 -9.494 1.00 153.00 ? 242 LYS Q CA 1 +ATOM 32220 C C . LYS Q 1 242 ? 9.251 24.571 -10.220 1.00 162.76 ? 242 LYS Q C 1 +ATOM 32221 O O . LYS Q 1 242 ? 10.198 25.346 -10.414 1.00 119.84 ? 242 LYS Q O 1 +ATOM 32222 C CB . LYS Q 1 242 ? 9.916 22.153 -10.470 1.00 159.22 ? 242 LYS Q CB 1 +ATOM 32223 C CG . LYS Q 1 242 ? 9.948 20.754 -9.860 1.00 169.42 ? 242 LYS Q CG 1 +ATOM 32224 C CD . LYS Q 1 242 ? 11.301 20.083 -10.028 1.00 165.56 ? 242 LYS Q CD 1 +ATOM 32225 C CE . LYS Q 1 242 ? 11.766 19.446 -8.727 1.00 161.30 ? 242 LYS Q CE 1 +ATOM 32226 N NZ . LYS Q 1 242 ? 13.011 18.648 -8.894 1.00 174.24 ? 242 LYS Q NZ 1 +ATOM 32227 N N . ALA Q 1 243 ? 7.986 24.837 -10.554 1.00 197.97 ? 243 ALA Q N 1 +ATOM 32228 C CA . ALA Q 1 243 ? 7.543 26.114 -11.121 1.00 199.58 ? 243 ALA Q CA 1 +ATOM 32229 C C . ALA Q 1 243 ? 7.782 27.275 -10.165 1.00 197.69 ? 243 ALA Q C 1 +ATOM 32230 O O . ALA Q 1 243 ? 7.803 28.431 -10.593 1.00 211.75 ? 243 ALA Q O 1 +ATOM 32231 C CB . ALA Q 1 243 ? 6.062 26.044 -11.484 1.00 194.85 ? 243 ALA Q CB 1 +ATOM 32232 N N . GLU Q 1 244 ? 7.945 26.976 -8.874 1.00 187.59 ? 244 GLU Q N 1 +ATOM 32233 C CA . GLU Q 1 244 ? 8.131 28.029 -7.883 1.00 159.48 ? 244 GLU Q CA 1 +ATOM 32234 C C . GLU Q 1 244 ? 9.602 28.347 -7.636 1.00 149.58 ? 244 GLU Q C 1 +ATOM 32235 O O . GLU Q 1 244 ? 9.911 29.054 -6.693 1.00 130.82 ? 244 GLU Q O 1 +ATOM 32236 C CB . GLU Q 1 244 ? 7.448 27.659 -6.567 1.00 152.83 ? 244 GLU Q CB 1 +ATOM 32237 C CG . GLU Q 1 244 ? 5.939 27.746 -6.608 1.00 157.28 ? 244 GLU Q CG 1 +ATOM 32238 C CD . GLU Q 1 244 ? 5.316 27.644 -5.224 1.00 166.35 ? 244 GLU Q CD 1 +ATOM 32239 O OE1 . GLU Q 1 244 ? 5.215 26.503 -4.703 1.00 134.43 ? 244 GLU Q OE1 1 +ATOM 32240 O OE2 . GLU Q 1 244 ? 4.860 28.699 -4.704 1.00 118.99 ? 244 GLU Q OE2 1 +ATOM 32241 N N . ARG Q 1 245 ? 10.499 27.815 -8.467 1.00 145.62 ? 245 ARG Q N 1 +ATOM 32242 C CA . ARG Q 1 245 ? 11.913 28.167 -8.382 1.00 157.85 ? 245 ARG Q CA 1 +ATOM 32243 C C . ARG Q 1 245 ? 12.168 29.671 -8.510 1.00 188.68 ? 245 ARG Q C 1 +ATOM 32244 O O . ARG Q 1 245 ? 13.061 30.201 -7.849 1.00 230.77 ? 245 ARG Q O 1 +ATOM 32245 C CB . ARG Q 1 245 ? 12.737 27.452 -9.440 1.00 156.40 ? 245 ARG Q CB 1 +ATOM 32246 C CG . ARG Q 1 245 ? 14.245 27.642 -9.260 1.00 163.17 ? 245 ARG Q CG 1 +ATOM 32247 C CD . ARG Q 1 245 ? 15.080 26.828 -10.266 1.00 164.96 ? 245 ARG Q CD 1 +ATOM 32248 N NE . ARG Q 1 245 ? 15.564 25.571 -9.688 1.00 164.13 ? 245 ARG Q NE 1 +ATOM 32249 C CZ . ARG Q 1 245 ? 16.524 25.479 -8.765 1.00 177.85 ? 245 ARG Q CZ 1 +ATOM 32250 N NH1 . ARG Q 1 245 ? 17.098 26.567 -8.280 1.00 185.77 ? 245 ARG Q NH1 1 +ATOM 32251 N NH2 . ARG Q 1 245 ? 16.905 24.293 -8.303 1.00 164.31 ? 245 ARG Q NH2 1 +ATOM 32252 N N . GLN Q 1 246 ? 11.396 30.350 -9.357 1.00 194.27 ? 246 GLN Q N 1 +ATOM 32253 C CA . GLN Q 1 246 ? 11.603 31.784 -9.593 1.00 170.10 ? 246 GLN Q CA 1 +ATOM 32254 C C . GLN Q 1 246 ? 10.734 32.638 -8.666 1.00 161.10 ? 246 GLN Q C 1 +ATOM 32255 O O . GLN Q 1 246 ? 10.460 33.797 -8.959 1.00 175.95 ? 246 GLN Q O 1 +ATOM 32256 C CB . GLN Q 1 246 ? 11.333 32.145 -11.059 1.00 158.16 ? 246 GLN Q CB 1 +ATOM 32257 C CG . GLN Q 1 246 ? 12.374 31.628 -12.033 1.00 162.18 ? 246 GLN Q CG 1 +ATOM 32258 C CD . GLN Q 1 246 ? 12.232 30.144 -12.289 1.00 196.34 ? 246 GLN Q CD 1 +ATOM 32259 O OE1 . GLN Q 1 246 ? 11.121 29.640 -12.503 1.00 232.28 ? 246 GLN Q OE1 1 +ATOM 32260 N NE2 . GLN Q 1 246 ? 13.355 29.433 -12.296 1.00 208.80 ? 246 GLN Q NE2 1 +ATOM 32261 N N . ASN Q 1 247 ? 10.299 32.051 -7.555 1.00 136.38 ? 247 ASN Q N 1 +ATOM 32262 C CA . ASN Q 1 247 ? 9.689 32.792 -6.456 1.00 132.97 ? 247 ASN Q CA 1 +ATOM 32263 C C . ASN Q 1 247 ? 10.413 34.111 -6.180 1.00 144.17 ? 247 ASN Q C 1 +ATOM 32264 O O . ASN Q 1 247 ? 11.648 34.153 -6.165 1.00 161.54 ? 247 ASN Q O 1 +ATOM 32265 C CB . ASN Q 1 247 ? 9.726 31.932 -5.192 1.00 150.23 ? 247 ASN Q CB 1 +ATOM 32266 C CG . ASN Q 1 247 ? 8.633 32.287 -4.214 1.00 183.57 ? 247 ASN Q CG 1 +ATOM 32267 O OD1 . ASN Q 1 247 ? 8.890 32.847 -3.144 1.00 175.27 ? 247 ASN Q OD1 1 +ATOM 32268 N ND2 . ASN Q 1 247 ? 7.400 31.936 -4.564 1.00 224.27 ? 247 ASN Q ND2 1 +ATOM 32269 N N . ASP Q 1 248 ? 9.647 35.177 -5.932 1.00 168.15 ? 248 ASP Q N 1 +ATOM 32270 C CA . ASP Q 1 248 ? 10.216 36.524 -5.691 1.00 179.39 ? 248 ASP Q CA 1 +ATOM 32271 C C . ASP Q 1 248 ? 11.292 36.511 -4.601 1.00 173.26 ? 248 ASP Q C 1 +ATOM 32272 O O . ASP Q 1 248 ? 12.376 37.088 -4.754 1.00 167.56 ? 248 ASP Q O 1 +ATOM 32273 C CB . ASP Q 1 248 ? 9.119 37.515 -5.266 1.00 168.76 ? 248 ASP Q CB 1 +ATOM 32274 C CG . ASP Q 1 248 ? 8.178 37.879 -6.396 1.00 169.97 ? 248 ASP Q CG 1 +ATOM 32275 O OD1 . ASP Q 1 248 ? 8.634 38.019 -7.550 1.00 185.87 ? 248 ASP Q OD1 1 +ATOM 32276 O OD2 . ASP Q 1 248 ? 6.971 38.038 -6.124 1.00 188.00 ? 248 ASP Q OD2 1 +ATOM 32277 N N . ILE Q 1 249 ? 10.967 35.855 -3.493 1.00 154.84 ? 249 ILE Q N 1 +ATOM 32278 C CA . ILE Q 1 249 ? 11.844 35.798 -2.346 1.00 136.51 ? 249 ILE Q CA 1 +ATOM 32279 C C . ILE Q 1 249 ? 13.116 35.020 -2.692 1.00 132.90 ? 249 ILE Q C 1 +ATOM 32280 O O . ILE Q 1 249 ? 14.238 35.487 -2.455 1.00 154.06 ? 249 ILE Q O 1 +ATOM 32281 C CB . ILE Q 1 249 ? 11.121 35.142 -1.152 1.00 143.13 ? 249 ILE Q CB 1 +ATOM 32282 C CG1 . ILE Q 1 249 ? 9.901 35.981 -0.737 1.00 120.34 ? 249 ILE Q CG1 1 +ATOM 32283 C CG2 . ILE Q 1 249 ? 12.070 35.004 0.030 1.00 181.48 ? 249 ILE Q CG2 1 +ATOM 32284 C CD1 . ILE Q 1 249 ? 8.863 35.228 0.076 1.00 106.77 ? 249 ILE Q CD1 1 +ATOM 32285 N N . LEU Q 1 250 ? 12.934 33.832 -3.261 1.00 132.64 ? 250 LEU Q N 1 +ATOM 32286 C CA . LEU Q 1 250 ? 14.061 32.961 -3.606 1.00 141.81 ? 250 LEU Q CA 1 +ATOM 32287 C C . LEU Q 1 250 ? 15.049 33.610 -4.583 1.00 143.09 ? 250 LEU Q C 1 +ATOM 32288 O O . LEU Q 1 250 ? 16.263 33.426 -4.454 1.00 121.99 ? 250 LEU Q O 1 +ATOM 32289 C CB . LEU Q 1 250 ? 13.559 31.635 -4.183 1.00 129.83 ? 250 LEU Q CB 1 +ATOM 32290 C CG . LEU Q 1 250 ? 13.074 30.617 -3.148 1.00 129.97 ? 250 LEU Q CG 1 +ATOM 32291 C CD1 . LEU Q 1 250 ? 12.336 29.462 -3.800 1.00 137.47 ? 250 LEU Q CD1 1 +ATOM 32292 C CD2 . LEU Q 1 250 ? 14.253 30.090 -2.348 1.00 157.17 ? 250 LEU Q CD2 1 +ATOM 32293 N N . VAL Q 1 251 ? 14.526 34.366 -5.544 1.00 151.77 ? 251 VAL Q N 1 +ATOM 32294 C CA . VAL Q 1 251 ? 15.381 35.055 -6.510 1.00 158.11 ? 251 VAL Q CA 1 +ATOM 32295 C C . VAL Q 1 251 ? 16.022 36.301 -5.902 1.00 158.83 ? 251 VAL Q C 1 +ATOM 32296 O O . VAL Q 1 251 ? 17.077 36.752 -6.358 1.00 157.61 ? 251 VAL Q O 1 +ATOM 32297 C CB . VAL Q 1 251 ? 14.616 35.439 -7.800 1.00 158.31 ? 251 VAL Q CB 1 +ATOM 32298 C CG1 . VAL Q 1 251 ? 13.968 34.205 -8.425 1.00 146.40 ? 251 VAL Q CG1 1 +ATOM 32299 C CG2 . VAL Q 1 251 ? 13.589 36.538 -7.538 1.00 140.63 ? 251 VAL Q CG2 1 +ATOM 32300 N N . LYS Q 1 252 ? 15.371 36.867 -4.891 1.00 156.43 ? 252 LYS Q N 1 +ATOM 32301 C CA . LYS Q 1 252 ? 15.926 38.007 -4.167 1.00 158.04 ? 252 LYS Q CA 1 +ATOM 32302 C C . LYS Q 1 252 ? 17.193 37.593 -3.393 1.00 187.42 ? 252 LYS Q C 1 +ATOM 32303 O O . LYS Q 1 252 ? 18.237 38.253 -3.480 1.00 168.01 ? 252 LYS Q O 1 +ATOM 32304 C CB . LYS Q 1 252 ? 14.858 38.571 -3.229 1.00 129.74 ? 252 LYS Q CB 1 +ATOM 32305 C CG . LYS Q 1 252 ? 15.302 39.746 -2.378 1.00 131.45 ? 252 LYS Q CG 1 +ATOM 32306 C CD . LYS Q 1 252 ? 14.162 40.191 -1.469 1.00 137.44 ? 252 LYS Q CD 1 +ATOM 32307 C CE . LYS Q 1 252 ? 14.628 40.386 -0.030 1.00 139.13 ? 252 LYS Q CE 1 +ATOM 32308 N NZ . LYS Q 1 252 ? 13.496 40.563 0.920 1.00 121.85 ? 252 LYS Q NZ 1 +ATOM 32309 N N . TYR Q 1 253 ? 17.114 36.460 -2.694 1.00 208.74 ? 253 TYR Q N 1 +ATOM 32310 C CA . TYR Q 1 253 ? 18.246 35.944 -1.909 1.00 174.38 ? 253 TYR Q CA 1 +ATOM 32311 C C . TYR Q 1 253 ? 19.286 35.286 -2.802 1.00 175.06 ? 253 TYR Q C 1 +ATOM 32312 O O . TYR Q 1 253 ? 20.486 35.330 -2.510 1.00 165.38 ? 253 TYR Q O 1 +ATOM 32313 C CB . TYR Q 1 253 ? 17.765 34.972 -0.823 1.00 147.64 ? 253 TYR Q CB 1 +ATOM 32314 C CG . TYR Q 1 253 ? 17.037 35.699 0.294 1.00 157.40 ? 253 TYR Q CG 1 +ATOM 32315 C CD1 . TYR Q 1 253 ? 17.739 36.298 1.335 1.00 149.77 ? 253 TYR Q CD1 1 +ATOM 32316 C CD2 . TYR Q 1 253 ? 15.646 35.866 0.264 1.00 163.50 ? 253 TYR Q CD2 1 +ATOM 32317 C CE1 . TYR Q 1 253 ? 17.071 37.007 2.327 1.00 152.56 ? 253 TYR Q CE1 1 +ATOM 32318 C CE2 . TYR Q 1 253 ? 14.971 36.579 1.256 1.00 126.20 ? 253 TYR Q CE2 1 +ATOM 32319 C CZ . TYR Q 1 253 ? 15.688 37.151 2.280 1.00 131.92 ? 253 TYR Q CZ 1 +ATOM 32320 O OH . TYR Q 1 253 ? 15.045 37.787 3.306 1.00 100.86 ? 253 TYR Q OH 1 +ATOM 32321 N N . ARG Q 1 254 ? 18.820 34.693 -3.900 1.00 161.52 ? 254 ARG Q N 1 +ATOM 32322 C CA . ARG Q 1 254 ? 19.715 34.213 -4.951 1.00 163.62 ? 254 ARG Q CA 1 +ATOM 32323 C C . ARG Q 1 254 ? 20.566 35.365 -5.493 1.00 150.74 ? 254 ARG Q C 1 +ATOM 32324 O O . ARG Q 1 254 ? 21.764 35.199 -5.751 1.00 118.23 ? 254 ARG Q O 1 +ATOM 32325 C CB . ARG Q 1 254 ? 18.911 33.579 -6.096 1.00 168.16 ? 254 ARG Q CB 1 +ATOM 32326 C CG . ARG Q 1 254 ? 19.781 32.949 -7.174 1.00 179.91 ? 254 ARG Q CG 1 +ATOM 32327 C CD . ARG Q 1 254 ? 19.017 31.991 -8.074 1.00 164.13 ? 254 ARG Q CD 1 +ATOM 32328 N NE . ARG Q 1 254 ? 18.535 30.801 -7.378 1.00 184.34 ? 254 ARG Q NE 1 +ATOM 32329 C CZ . ARG Q 1 254 ? 17.267 30.558 -7.060 1.00 182.51 ? 254 ARG Q CZ 1 +ATOM 32330 N NH1 . ARG Q 1 254 ? 16.311 31.419 -7.366 1.00 164.46 ? 254 ARG Q NH1 1 +ATOM 32331 N NH2 . ARG Q 1 254 ? 16.955 29.434 -6.419 1.00 187.35 ? 254 ARG Q NH2 1 +ATOM 32332 N N . HIS Q 1 255 ? 19.930 36.526 -5.660 1.00 145.06 ? 255 HIS Q N 1 +ATOM 32333 C CA . HIS Q 1 255 ? 20.605 37.721 -6.159 1.00 154.45 ? 255 HIS Q CA 1 +ATOM 32334 C C . HIS Q 1 255 ? 21.634 38.283 -5.174 1.00 175.14 ? 255 HIS Q C 1 +ATOM 32335 O O . HIS Q 1 255 ? 22.671 38.804 -5.582 1.00 176.72 ? 255 HIS Q O 1 +ATOM 32336 C CB . HIS Q 1 255 ? 19.585 38.803 -6.543 1.00 166.31 ? 255 HIS Q CB 1 +ATOM 32337 C CG . HIS Q 1 255 ? 19.412 38.958 -8.022 1.00 199.13 ? 255 HIS Q CG 1 +ATOM 32338 N ND1 . HIS Q 1 255 ? 18.728 38.043 -8.792 1.00 208.67 ? 255 HIS Q ND1 1 +ATOM 32339 C CD2 . HIS Q 1 255 ? 19.891 39.888 -8.883 1.00 217.68 ? 255 HIS Q CD2 1 +ATOM 32340 C CE1 . HIS Q 1 255 ? 18.765 38.417 -10.059 1.00 193.87 ? 255 HIS Q CE1 1 +ATOM 32341 N NE2 . HIS Q 1 255 ? 19.467 39.533 -10.141 1.00 211.32 ? 255 HIS Q NE2 1 +ATOM 32342 N N . MET Q 1 256 ? 21.354 38.185 -3.877 1.00 184.71 ? 256 MET Q N 1 +ATOM 32343 C CA . MET Q 1 256 ? 22.297 38.690 -2.872 1.00 152.17 ? 256 MET Q CA 1 +ATOM 32344 C C . MET Q 1 256 ? 23.596 37.856 -2.844 1.00 152.63 ? 256 MET Q C 1 +ATOM 32345 O O . MET Q 1 256 ? 24.646 38.360 -2.434 1.00 112.23 ? 256 MET Q O 1 +ATOM 32346 C CB . MET Q 1 256 ? 21.631 38.744 -1.490 1.00 160.21 ? 256 MET Q CB 1 +ATOM 32347 C CG . MET Q 1 256 ? 20.317 39.521 -1.475 1.00 166.72 ? 256 MET Q CG 1 +ATOM 32348 S SD . MET Q 1 256 ? 19.754 40.076 0.145 1.00 204.90 ? 256 MET Q SD 1 +ATOM 32349 C CE . MET Q 1 256 ? 20.990 41.325 0.508 1.00 199.85 ? 256 MET Q CE 1 +ATOM 32350 N N . SER Q 1 257 ? 23.518 36.594 -3.294 1.00 152.50 ? 257 SER Q N 1 +ATOM 32351 C CA . SER Q 1 257 ? 24.690 35.687 -3.365 1.00 115.11 ? 257 SER Q CA 1 +ATOM 32352 C C . SER Q 1 257 ? 25.634 36.028 -4.508 1.00 115.86 ? 257 SER Q C 1 +ATOM 32353 O O . SER Q 1 257 ? 26.550 36.830 -4.363 1.00 62.98 ? 257 SER Q O 1 +ATOM 32354 C CB . SER Q 1 257 ? 24.236 34.231 -3.530 1.00 84.10 ? 257 SER Q CB 1 +ATOM 32355 O OG . SER Q 1 257 ? 23.187 33.938 -2.638 1.00 77.73 ? 257 SER Q OG 1 +ATOM 32356 N N . LEU R 1 2 ? 3.443 54.964 20.571 1.00 158.47 ? 2 LEU R N 1 +ATOM 32357 C CA . LEU R 1 2 ? 4.933 54.933 20.385 1.00 169.74 ? 2 LEU R CA 1 +ATOM 32358 C C . LEU R 1 2 ? 5.660 54.845 21.754 1.00 182.45 ? 2 LEU R C 1 +ATOM 32359 O O . LEU R 1 2 ? 6.304 55.811 22.221 1.00 136.59 ? 2 LEU R O 1 +ATOM 32360 C CB . LEU R 1 2 ? 5.411 56.135 19.555 1.00 155.28 ? 2 LEU R CB 1 +ATOM 32361 C CG . LEU R 1 2 ? 4.892 56.301 18.105 1.00 119.63 ? 2 LEU R CG 1 +ATOM 32362 C CD1 . LEU R 1 2 ? 5.482 57.575 17.505 1.00 109.27 ? 2 LEU R CD1 1 +ATOM 32363 C CD2 . LEU R 1 2 ? 5.160 55.103 17.189 1.00 89.31 ? 2 LEU R CD2 1 +ATOM 32364 N N . THR R 1 3 ? 5.396 53.727 22.435 1.00 219.43 ? 3 THR R N 1 +ATOM 32365 C CA . THR R 1 3 ? 6.161 53.250 23.596 1.00 204.50 ? 3 THR R CA 1 +ATOM 32366 C C . THR R 1 3 ? 6.322 51.713 23.531 1.00 176.94 ? 3 THR R C 1 +ATOM 32367 O O . THR R 1 3 ? 6.939 51.089 24.405 1.00 106.93 ? 3 THR R O 1 +ATOM 32368 C CB . THR R 1 3 ? 5.483 53.621 24.940 1.00 195.76 ? 3 THR R CB 1 +ATOM 32369 O OG1 . THR R 1 3 ? 4.253 52.888 25.085 1.00 150.26 ? 3 THR R OG1 1 +ATOM 32370 C CG2 . THR R 1 3 ? 5.240 55.137 25.041 1.00 159.21 ? 3 THR R CG2 1 +ATOM 32371 N N . ALA R 1 4 ? 5.691 51.108 22.531 1.00 150.77 ? 4 ALA R N 1 +ATOM 32372 C CA . ALA R 1 4 ? 6.079 49.780 22.071 1.00 111.58 ? 4 ALA R CA 1 +ATOM 32373 C C . ALA R 1 4 ? 7.408 49.914 21.296 1.00 78.78 ? 4 ALA R C 1 +ATOM 32374 O O . ALA R 1 4 ? 8.011 50.973 21.264 1.00 52.30 ? 4 ALA R O 1 +ATOM 32375 C CB . ALA R 1 4 ? 4.948 49.164 21.232 1.00 91.38 ? 4 ALA R CB 1 +ATOM 32376 N N . PRO R 1 5 ? 7.900 48.829 20.713 1.00 85.11 ? 5 PRO R N 1 +ATOM 32377 C CA . PRO R 1 5 ? 9.270 49.016 20.272 1.00 85.47 ? 5 PRO R CA 1 +ATOM 32378 C C . PRO R 1 5 ? 9.379 49.845 18.974 1.00 75.84 ? 5 PRO R C 1 +ATOM 32379 O O . PRO R 1 5 ? 8.400 50.025 18.272 1.00 50.61 ? 5 PRO R O 1 +ATOM 32380 C CB . PRO R 1 5 ? 9.765 47.558 20.092 1.00 99.24 ? 5 PRO R CB 1 +ATOM 32381 C CG . PRO R 1 5 ? 8.533 46.741 19.794 1.00 98.86 ? 5 PRO R CG 1 +ATOM 32382 C CD . PRO R 1 5 ? 7.333 47.526 20.280 1.00 99.61 ? 5 PRO R CD 1 +ATOM 32383 N N . PRO R 1 6 ? 10.599 50.190 18.576 1.00 75.19 ? 6 PRO R N 1 +ATOM 32384 C CA . PRO R 1 6 ? 10.906 50.601 17.196 1.00 74.40 ? 6 PRO R CA 1 +ATOM 32385 C C . PRO R 1 6 ? 11.036 49.461 16.188 1.00 68.08 ? 6 PRO R C 1 +ATOM 32386 O O . PRO R 1 6 ? 11.421 48.363 16.541 1.00 79.67 ? 6 PRO R O 1 +ATOM 32387 C CB . PRO R 1 6 ? 12.236 51.339 17.329 1.00 83.25 ? 6 PRO R CB 1 +ATOM 32388 C CG . PRO R 1 6 ? 12.823 50.891 18.620 1.00 96.69 ? 6 PRO R CG 1 +ATOM 32389 C CD . PRO R 1 6 ? 11.751 50.279 19.480 1.00 77.42 ? 6 PRO R CD 1 +ATOM 32390 N N . LYS R 1 7 ? 10.726 49.731 14.932 1.00 81.71 ? 7 LYS R N 1 +ATOM 32391 C CA . LYS R 1 7 ? 10.802 48.710 13.884 1.00 118.11 ? 7 LYS R CA 1 +ATOM 32392 C C . LYS R 1 7 ? 12.135 48.730 13.129 1.00 131.21 ? 7 LYS R C 1 +ATOM 32393 O O . LYS R 1 7 ? 12.937 49.658 13.273 1.00 92.75 ? 7 LYS R O 1 +ATOM 32394 C CB . LYS R 1 7 ? 9.633 48.856 12.898 1.00 150.46 ? 7 LYS R CB 1 +ATOM 32395 C CG . LYS R 1 7 ? 8.280 48.511 13.483 1.00 159.35 ? 7 LYS R CG 1 +ATOM 32396 C CD . LYS R 1 7 ? 7.426 49.741 13.782 1.00 158.53 ? 7 LYS R CD 1 +ATOM 32397 C CE . LYS R 1 7 ? 5.989 49.335 14.056 1.00 143.77 ? 7 LYS R CE 1 +ATOM 32398 N NZ . LYS R 1 7 ? 5.312 50.284 14.974 1.00 141.45 ? 7 LYS R NZ 1 +ATOM 32399 N N . GLU R 1 8 ? 12.342 47.712 12.292 1.00 154.03 ? 8 GLU R N 1 +ATOM 32400 C CA . GLU R 1 8 ? 13.657 47.418 11.721 1.00 166.85 ? 8 GLU R CA 1 +ATOM 32401 C C . GLU R 1 8 ? 14.189 48.523 10.771 1.00 134.68 ? 8 GLU R C 1 +ATOM 32402 O O . GLU R 1 8 ? 13.605 48.818 9.737 1.00 111.88 ? 8 GLU R O 1 +ATOM 32403 C CB . GLU R 1 8 ? 13.656 46.024 11.057 1.00 191.36 ? 8 GLU R CB 1 +ATOM 32404 C CG . GLU R 1 8 ? 14.344 44.871 11.863 1.00 201.84 ? 8 GLU R CG 1 +ATOM 32405 C CD . GLU R 1 8 ? 13.420 43.696 12.235 1.00 187.76 ? 8 GLU R CD 1 +ATOM 32406 O OE1 . GLU R 1 8 ? 12.307 43.988 12.747 1.00 175.03 ? 8 GLU R OE1 1 +ATOM 32407 O OE2 . GLU R 1 8 ? 13.842 42.494 12.121 1.00 122.79 ? 8 GLU R OE2 1 +ATOM 32408 N N . ALA R 1 9 ? 15.298 49.142 11.167 1.00 128.07 ? 9 ALA R N 1 +ATOM 32409 C CA . ALA R 1 9 ? 16.055 50.069 10.331 1.00 108.19 ? 9 ALA R CA 1 +ATOM 32410 C C . ALA R 1 9 ? 17.248 49.367 9.647 1.00 113.80 ? 9 ALA R C 1 +ATOM 32411 O O . ALA R 1 9 ? 18.204 48.958 10.313 1.00 136.81 ? 9 ALA R O 1 +ATOM 32412 C CB . ALA R 1 9 ? 16.559 51.222 11.186 1.00 93.89 ? 9 ALA R CB 1 +ATOM 32413 N N . ALA R 1 10 ? 17.165 49.225 8.324 1.00 101.27 ? 10 ALA R N 1 +ATOM 32414 C CA . ALA R 1 10 ? 18.125 48.461 7.499 1.00 102.87 ? 10 ALA R CA 1 +ATOM 32415 C C . ALA R 1 10 ? 17.787 46.972 7.478 1.00 121.97 ? 10 ALA R C 1 +ATOM 32416 O O . ALA R 1 10 ? 17.058 46.484 8.348 1.00 89.26 ? 10 ALA R O 1 +ATOM 32417 C CB . ALA R 1 10 ? 19.570 48.674 7.942 1.00 95.28 ? 10 ALA R CB 1 +ATOM 32418 N N . ARG R 1 11 ? 18.325 46.268 6.473 1.00 149.47 ? 11 ARG R N 1 +ATOM 32419 C CA . ARG R 1 11 ? 18.101 44.828 6.289 1.00 137.54 ? 11 ARG R CA 1 +ATOM 32420 C C . ARG R 1 11 ? 19.348 44.031 6.678 1.00 119.24 ? 11 ARG R C 1 +ATOM 32421 O O . ARG R 1 11 ? 20.475 44.499 6.518 1.00 103.32 ? 11 ARG R O 1 +ATOM 32422 C CB . ARG R 1 11 ? 17.747 44.507 4.822 1.00 129.26 ? 11 ARG R CB 1 +ATOM 32423 C CG . ARG R 1 11 ? 18.884 44.729 3.830 1.00 147.30 ? 11 ARG R CG 1 +ATOM 32424 C CD . ARG R 1 11 ? 18.351 45.051 2.435 1.00 142.70 ? 11 ARG R CD 1 +ATOM 32425 N NE . ARG R 1 11 ? 18.587 46.446 2.064 1.00 152.75 ? 11 ARG R NE 1 +ATOM 32426 C CZ . ARG R 1 11 ? 18.238 46.978 0.894 1.00 148.14 ? 11 ARG R CZ 1 +ATOM 32427 N NH1 . ARG R 1 11 ? 17.699 46.214 -0.044 1.00 159.90 ? 11 ARG R NH1 1 +ATOM 32428 N NH2 . ARG R 1 11 ? 18.459 48.266 0.644 1.00 128.59 ? 11 ARG R NH2 1 +ATOM 32429 N N . PRO R 1 12 ? 19.152 42.806 7.171 1.00 104.23 ? 12 PRO R N 1 +ATOM 32430 C CA . PRO R 1 12 ? 20.288 41.920 7.209 1.00 102.43 ? 12 PRO R CA 1 +ATOM 32431 C C . PRO R 1 12 ? 20.790 41.643 5.778 1.00 86.20 ? 12 PRO R C 1 +ATOM 32432 O O . PRO R 1 12 ? 20.105 40.996 4.987 1.00 142.47 ? 12 PRO R O 1 +ATOM 32433 C CB . PRO R 1 12 ? 19.721 40.635 7.875 1.00 116.87 ? 12 PRO R CB 1 +ATOM 32434 C CG . PRO R 1 12 ? 18.380 41.002 8.430 1.00 96.33 ? 12 PRO R CG 1 +ATOM 32435 C CD . PRO R 1 12 ? 17.903 42.117 7.544 1.00 114.96 ? 12 PRO R CD 1 +ATOM 32436 N N . THR R 1 13 ? 21.981 42.102 5.468 1.00 58.12 ? 13 THR R N 1 +ATOM 32437 C CA . THR R 1 13 ? 22.705 41.606 4.312 1.00 67.60 ? 13 THR R CA 1 +ATOM 32438 C C . THR R 1 13 ? 23.547 40.361 4.657 1.00 78.09 ? 13 THR R C 1 +ATOM 32439 O O . THR R 1 13 ? 23.881 40.146 5.824 1.00 162.78 ? 13 THR R O 1 +ATOM 32440 C CB . THR R 1 13 ? 23.619 42.719 3.793 1.00 75.22 ? 13 THR R CB 1 +ATOM 32441 O OG1 . THR R 1 13 ? 24.177 42.350 2.526 1.00 73.51 ? 13 THR R OG1 1 +ATOM 32442 C CG2 . THR R 1 13 ? 24.776 43.035 4.799 1.00 85.45 ? 13 THR R CG2 1 +ATOM 32443 N N . LEU R 1 14 ? 23.982 39.587 3.667 1.00 83.31 ? 14 LEU R N 1 +ATOM 32444 C CA . LEU R 1 14 ? 25.045 38.604 3.954 1.00 101.49 ? 14 LEU R CA 1 +ATOM 32445 C C . LEU R 1 14 ? 26.412 39.317 4.122 1.00 100.23 ? 14 LEU R C 1 +ATOM 32446 O O . LEU R 1 14 ? 26.527 40.474 3.756 1.00 78.23 ? 14 LEU R O 1 +ATOM 32447 C CB . LEU R 1 14 ? 25.106 37.464 2.938 1.00 112.27 ? 14 LEU R CB 1 +ATOM 32448 C CG . LEU R 1 14 ? 25.247 37.812 1.465 1.00 120.64 ? 14 LEU R CG 1 +ATOM 32449 C CD1 . LEU R 1 14 ? 26.069 36.753 0.749 1.00 133.21 ? 14 LEU R CD1 1 +ATOM 32450 C CD2 . LEU R 1 14 ? 23.869 37.914 0.855 1.00 95.30 ? 14 LEU R CD2 1 +ATOM 32451 N N . MET R 1 15 ? 27.372 38.697 4.821 1.00 132.07 ? 15 MET R N 1 +ATOM 32452 C CA . MET R 1 15 ? 28.423 39.478 5.546 1.00 139.91 ? 15 MET R CA 1 +ATOM 32453 C C . MET R 1 15 ? 29.382 40.109 4.565 1.00 123.72 ? 15 MET R C 1 +ATOM 32454 O O . MET R 1 15 ? 29.957 39.419 3.728 1.00 103.20 ? 15 MET R O 1 +ATOM 32455 C CB . MET R 1 15 ? 29.235 38.664 6.548 1.00 123.35 ? 15 MET R CB 1 +ATOM 32456 C CG . MET R 1 15 ? 30.349 39.478 7.263 1.00 113.16 ? 15 MET R CG 1 +ATOM 32457 S SD . MET R 1 15 ? 30.049 39.582 8.909 1.00 100.69 ? 15 MET R SD 1 +ATOM 32458 C CE . MET R 1 15 ? 31.681 39.182 9.545 1.00 112.85 ? 15 MET R CE 1 +ATOM 32459 N N . PRO R 1 16 ? 29.537 41.435 4.658 1.00 101.79 ? 16 PRO R N 1 +ATOM 32460 C CA . PRO R 1 16 ? 30.255 42.233 3.666 1.00 101.25 ? 16 PRO R CA 1 +ATOM 32461 C C . PRO R 1 16 ? 31.746 41.919 3.609 1.00 87.56 ? 16 PRO R C 1 +ATOM 32462 O O . PRO R 1 16 ? 32.574 42.659 4.141 1.00 92.61 ? 16 PRO R O 1 +ATOM 32463 C CB . PRO R 1 16 ? 29.995 43.676 4.127 1.00 116.82 ? 16 PRO R CB 1 +ATOM 32464 C CG . PRO R 1 16 ? 29.675 43.545 5.574 1.00 112.61 ? 16 PRO R CG 1 +ATOM 32465 C CD . PRO R 1 16 ? 28.905 42.282 5.685 1.00 90.30 ? 16 PRO R CD 1 +ATOM 32466 N N . ARG R 1 17 ? 32.090 40.879 2.870 1.00 104.70 ? 17 ARG R N 1 +ATOM 32467 C CA . ARG R 1 17 ? 33.482 40.592 2.561 1.00 130.28 ? 17 ARG R CA 1 +ATOM 32468 C C . ARG R 1 17 ? 33.933 41.400 1.334 1.00 108.53 ? 17 ARG R C 1 +ATOM 32469 O O . ARG R 1 17 ? 33.158 41.549 0.402 1.00 108.11 ? 17 ARG R O 1 +ATOM 32470 C CB . ARG R 1 17 ? 33.644 39.072 2.361 1.00 131.39 ? 17 ARG R CB 1 +ATOM 32471 C CG . ARG R 1 17 ? 33.866 38.312 3.670 1.00 144.91 ? 17 ARG R CG 1 +ATOM 32472 C CD . ARG R 1 17 ? 33.608 36.822 3.546 1.00 159.42 ? 17 ARG R CD 1 +ATOM 32473 N NE . ARG R 1 17 ? 32.187 36.512 3.577 1.00 149.25 ? 17 ARG R NE 1 +ATOM 32474 C CZ . ARG R 1 17 ? 31.682 35.306 3.335 1.00 98.60 ? 17 ARG R CZ 1 +ATOM 32475 N NH1 . ARG R 1 17 ? 32.496 34.301 3.044 1.00 86.31 ? 17 ARG R NH1 1 +ATOM 32476 N NH2 . ARG R 1 17 ? 30.369 35.109 3.403 1.00 72.84 ? 17 ARG R NH2 1 +ATOM 32477 N N . ALA R 1 18 ? 35.196 41.835 1.304 1.00 84.93 ? 18 ALA R N 1 +ATOM 32478 C CA . ALA R 1 18 ? 35.716 42.557 0.155 1.00 87.96 ? 18 ALA R CA 1 +ATOM 32479 C C . ALA R 1 18 ? 36.767 41.767 -0.691 1.00 98.67 ? 18 ALA R C 1 +ATOM 32480 O O . ALA R 1 18 ? 36.429 40.763 -1.351 1.00 116.91 ? 18 ALA R O 1 +ATOM 32481 C CB . ALA R 1 18 ? 36.272 43.882 0.609 1.00 89.94 ? 18 ALA R CB 1 +ATOM 32482 N N . GLN R 1 19 ? 37.993 42.285 -0.787 1.00 103.23 ? 19 GLN R N 1 +ATOM 32483 C CA . GLN R 1 19 ? 38.887 41.954 -1.918 1.00 142.22 ? 19 GLN R CA 1 +ATOM 32484 C C . GLN R 1 19 ? 39.438 40.541 -1.790 1.00 140.58 ? 19 GLN R C 1 +ATOM 32485 O O . GLN R 1 19 ? 39.393 39.738 -2.742 1.00 181.86 ? 19 GLN R O 1 +ATOM 32486 C CB . GLN R 1 19 ? 40.059 42.942 -1.991 1.00 168.04 ? 19 GLN R CB 1 +ATOM 32487 C CG . GLN R 1 19 ? 40.991 42.744 -3.186 1.00 170.48 ? 19 GLN R CG 1 +ATOM 32488 C CD . GLN R 1 19 ? 40.251 42.771 -4.512 1.00 180.40 ? 19 GLN R CD 1 +ATOM 32489 O OE1 . GLN R 1 19 ? 39.718 43.805 -4.918 1.00 176.46 ? 19 GLN R OE1 1 +ATOM 32490 N NE2 . GLN R 1 19 ? 40.196 41.625 -5.185 1.00 197.33 ? 19 GLN R NE2 1 +ATOM 32491 N N . SER R 1 20 ? 39.954 40.257 -0.603 1.00 105.76 ? 20 SER R N 1 +ATOM 32492 C CA . SER R 1 20 ? 40.372 38.929 -0.239 1.00 108.98 ? 20 SER R CA 1 +ATOM 32493 C C . SER R 1 20 ? 39.355 37.872 -0.717 1.00 135.21 ? 20 SER R C 1 +ATOM 32494 O O . SER R 1 20 ? 39.726 36.874 -1.346 1.00 145.53 ? 20 SER R O 1 +ATOM 32495 C CB . SER R 1 20 ? 40.526 38.871 1.281 1.00 121.61 ? 20 SER R CB 1 +ATOM 32496 O OG . SER R 1 20 ? 41.321 39.947 1.755 1.00 79.91 ? 20 SER R OG 1 +ATOM 32497 N N . TYR R 1 21 ? 38.075 38.087 -0.398 1.00 143.72 ? 21 TYR R N 1 +ATOM 32498 C CA . TYR R 1 21 ? 36.987 37.186 -0.813 1.00 145.26 ? 21 TYR R CA 1 +ATOM 32499 C C . TYR R 1 21 ? 36.949 36.993 -2.331 1.00 147.46 ? 21 TYR R C 1 +ATOM 32500 O O . TYR R 1 21 ? 36.852 35.867 -2.825 1.00 100.60 ? 21 TYR R O 1 +ATOM 32501 C CB . TYR R 1 21 ? 35.632 37.731 -0.325 1.00 155.09 ? 21 TYR R CB 1 +ATOM 32502 C CG . TYR R 1 21 ? 34.456 36.845 -0.668 1.00 181.50 ? 21 TYR R CG 1 +ATOM 32503 C CD1 . TYR R 1 21 ? 34.222 35.660 0.033 1.00 189.23 ? 21 TYR R CD1 1 +ATOM 32504 C CD2 . TYR R 1 21 ? 33.601 37.166 -1.718 1.00 190.23 ? 21 TYR R CD2 1 +ATOM 32505 C CE1 . TYR R 1 21 ? 33.173 34.823 -0.294 1.00 180.94 ? 21 TYR R CE1 1 +ATOM 32506 C CE2 . TYR R 1 21 ? 32.539 36.328 -2.049 1.00 196.41 ? 21 TYR R CE2 1 +ATOM 32507 C CZ . TYR R 1 21 ? 32.332 35.152 -1.330 1.00 167.63 ? 21 TYR R CZ 1 +ATOM 32508 O OH . TYR R 1 21 ? 31.274 34.314 -1.617 1.00 79.98 ? 21 TYR R OH 1 +ATOM 32509 N N . LYS R 1 22 ? 36.967 38.106 -3.061 1.00 187.06 ? 22 LYS R N 1 +ATOM 32510 C CA . LYS R 1 22 ? 36.865 38.083 -4.522 1.00 183.64 ? 22 LYS R CA 1 +ATOM 32511 C C . LYS R 1 22 ? 37.999 37.292 -5.160 1.00 171.60 ? 22 LYS R C 1 +ATOM 32512 O O . LYS R 1 22 ? 37.781 36.535 -6.110 1.00 201.89 ? 22 LYS R O 1 +ATOM 32513 C CB . LYS R 1 22 ? 36.863 39.509 -5.075 1.00 169.28 ? 22 LYS R CB 1 +ATOM 32514 C CG . LYS R 1 22 ? 35.482 40.119 -5.170 1.00 169.99 ? 22 LYS R CG 1 +ATOM 32515 C CD . LYS R 1 22 ? 34.782 39.649 -6.454 1.00 176.32 ? 22 LYS R CD 1 +ATOM 32516 C CE . LYS R 1 22 ? 34.838 40.746 -7.522 1.00 169.34 ? 22 LYS R CE 1 +ATOM 32517 N NZ . LYS R 1 22 ? 34.061 41.945 -7.109 1.00 187.44 ? 22 LYS R NZ 1 +ATOM 32518 N N . ASP R 1 23 ? 39.202 37.457 -4.616 1.00 151.97 ? 23 ASP R N 1 +ATOM 32519 C CA . ASP R 1 23 ? 40.354 36.663 -5.038 1.00 161.57 ? 23 ASP R CA 1 +ATOM 32520 C C . ASP R 1 23 ? 40.163 35.184 -4.700 1.00 159.07 ? 23 ASP R C 1 +ATOM 32521 O O . ASP R 1 23 ? 40.417 34.307 -5.529 1.00 147.53 ? 23 ASP R O 1 +ATOM 32522 C CB . ASP R 1 23 ? 41.621 37.172 -4.351 1.00 163.45 ? 23 ASP R CB 1 +ATOM 32523 C CG . ASP R 1 23 ? 42.013 38.543 -4.811 1.00 153.80 ? 23 ASP R CG 1 +ATOM 32524 O OD1 . ASP R 1 23 ? 41.927 38.787 -6.030 1.00 136.21 ? 23 ASP R OD1 1 +ATOM 32525 O OD2 . ASP R 1 23 ? 42.437 39.358 -3.957 1.00 181.59 ? 23 ASP R OD2 1 +ATOM 32526 N N . LEU R 1 24 ? 39.689 34.930 -3.483 1.00 146.23 ? 24 LEU R N 1 +ATOM 32527 C CA . LEU R 1 24 ? 39.558 33.576 -2.953 1.00 150.54 ? 24 LEU R CA 1 +ATOM 32528 C C . LEU R 1 24 ? 38.536 32.743 -3.733 1.00 155.67 ? 24 LEU R C 1 +ATOM 32529 O O . LEU R 1 24 ? 38.712 31.529 -3.924 1.00 162.81 ? 24 LEU R O 1 +ATOM 32530 C CB . LEU R 1 24 ? 39.148 33.648 -1.476 1.00 150.49 ? 24 LEU R CB 1 +ATOM 32531 C CG . LEU R 1 24 ? 38.965 32.328 -0.719 1.00 151.73 ? 24 LEU R CG 1 +ATOM 32532 C CD1 . LEU R 1 24 ? 40.291 31.823 -0.157 1.00 154.81 ? 24 LEU R CD1 1 +ATOM 32533 C CD2 . LEU R 1 24 ? 37.949 32.501 0.398 1.00 149.28 ? 24 LEU R CD2 1 +ATOM 32534 N N . THR R 1 25 ? 37.461 33.396 -4.173 1.00 171.42 ? 25 THR R N 1 +ATOM 32535 C CA . THR R 1 25 ? 36.385 32.717 -4.910 1.00 172.91 ? 25 THR R CA 1 +ATOM 32536 C C . THR R 1 25 ? 36.778 32.380 -6.360 1.00 151.25 ? 25 THR R C 1 +ATOM 32537 O O . THR R 1 25 ? 36.576 31.256 -6.818 1.00 82.68 ? 25 THR R O 1 +ATOM 32538 C CB . THR R 1 25 ? 35.095 33.567 -4.918 1.00 175.51 ? 25 THR R CB 1 +ATOM 32539 O OG1 . THR R 1 25 ? 35.414 34.928 -5.265 1.00 235.99 ? 25 THR R OG1 1 +ATOM 32540 C CG2 . THR R 1 25 ? 34.426 33.524 -3.549 1.00 133.49 ? 25 THR R CG2 1 +ATOM 32541 N N . HIS R 1 26 ? 37.357 33.361 -7.054 1.00 165.29 ? 26 HIS R N 1 +ATOM 32542 C CA . HIS R 1 26 ? 37.735 33.220 -8.461 1.00 152.29 ? 26 HIS R CA 1 +ATOM 32543 C C . HIS R 1 26 ? 39.108 32.541 -8.610 1.00 145.28 ? 26 HIS R C 1 +ATOM 32544 O O . HIS R 1 26 ? 39.902 32.889 -9.479 1.00 174.88 ? 26 HIS R O 1 +ATOM 32545 C CB . HIS R 1 26 ? 37.715 34.605 -9.155 1.00 156.72 ? 26 HIS R CB 1 +ATOM 32546 C CG . HIS R 1 26 ? 36.353 35.241 -9.215 1.00 169.09 ? 26 HIS R CG 1 +ATOM 32547 N ND1 . HIS R 1 26 ? 35.708 35.732 -8.099 1.00 173.32 ? 26 HIS R ND1 1 +ATOM 32548 C CD2 . HIS R 1 26 ? 35.511 35.457 -10.256 1.00 169.23 ? 26 HIS R CD2 1 +ATOM 32549 C CE1 . HIS R 1 26 ? 34.522 36.201 -8.445 1.00 160.19 ? 26 HIS R CE1 1 +ATOM 32550 N NE2 . HIS R 1 26 ? 34.377 36.047 -9.749 1.00 161.78 ? 26 HIS R NE2 1 +ATOM 32551 N N . LEU R 1 27 ? 39.406 31.589 -7.736 1.00 128.07 ? 27 LEU R N 1 +ATOM 32552 C CA . LEU R 1 27 ? 40.645 30.831 -7.845 1.00 127.46 ? 27 LEU R CA 1 +ATOM 32553 C C . LEU R 1 27 ? 40.403 29.626 -8.750 1.00 114.27 ? 27 LEU R C 1 +ATOM 32554 O O . LEU R 1 27 ? 39.415 28.917 -8.581 1.00 102.43 ? 27 LEU R O 1 +ATOM 32555 C CB . LEU R 1 27 ? 41.140 30.374 -6.457 1.00 150.84 ? 27 LEU R CB 1 +ATOM 32556 C CG . LEU R 1 27 ? 42.046 31.360 -5.710 1.00 158.72 ? 27 LEU R CG 1 +ATOM 32557 C CD1 . LEU R 1 27 ? 42.213 30.964 -4.252 1.00 154.42 ? 27 LEU R CD1 1 +ATOM 32558 C CD2 . LEU R 1 27 ? 43.411 31.464 -6.389 1.00 176.52 ? 27 LEU R CD2 1 +ATOM 32559 N N . PRO R 1 28 ? 41.346 29.347 -9.665 1.00 110.46 ? 28 PRO R N 1 +ATOM 32560 C CA . PRO R 1 28 ? 41.244 28.178 -10.554 1.00 114.11 ? 28 PRO R CA 1 +ATOM 32561 C C . PRO R 1 28 ? 41.151 26.869 -9.796 1.00 114.86 ? 28 PRO R C 1 +ATOM 32562 O O . PRO R 1 28 ? 41.976 26.615 -8.930 1.00 179.01 ? 28 PRO R O 1 +ATOM 32563 C CB . PRO R 1 28 ? 42.546 28.225 -11.350 1.00 118.74 ? 28 PRO R CB 1 +ATOM 32564 C CG . PRO R 1 28 ? 43.501 28.995 -10.481 1.00 111.33 ? 28 PRO R CG 1 +ATOM 32565 C CD . PRO R 1 28 ? 42.661 30.007 -9.764 1.00 109.61 ? 28 PRO R CD 1 +ATOM 32566 N N . ALA R 1 29 ? 40.154 26.050 -10.110 1.00 119.21 ? 29 ALA R N 1 +ATOM 32567 C CA . ALA R 1 29 ? 39.821 24.879 -9.284 1.00 106.56 ? 29 ALA R CA 1 +ATOM 32568 C C . ALA R 1 29 ? 40.873 23.732 -9.420 1.00 97.85 ? 29 ALA R C 1 +ATOM 32569 O O . ALA R 1 29 ? 41.512 23.573 -10.454 1.00 64.21 ? 29 ALA R O 1 +ATOM 32570 C CB . ALA R 1 29 ? 38.412 24.379 -9.609 1.00 88.50 ? 29 ALA R CB 1 +ATOM 32571 N N . PRO R 1 30 ? 41.088 22.967 -8.342 1.00 104.78 ? 30 PRO R N 1 +ATOM 32572 C CA . PRO R 1 30 ? 41.996 21.821 -8.328 1.00 101.92 ? 30 PRO R CA 1 +ATOM 32573 C C . PRO R 1 30 ? 41.363 20.613 -8.991 1.00 100.16 ? 30 PRO R C 1 +ATOM 32574 O O . PRO R 1 30 ? 40.178 20.654 -9.354 1.00 77.89 ? 30 PRO R O 1 +ATOM 32575 C CB . PRO R 1 30 ? 42.165 21.536 -6.846 1.00 123.16 ? 30 PRO R CB 1 +ATOM 32576 C CG . PRO R 1 30 ? 40.881 21.993 -6.223 1.00 133.25 ? 30 PRO R CG 1 +ATOM 32577 C CD . PRO R 1 30 ? 40.397 23.149 -7.051 1.00 123.37 ? 30 PRO R CD 1 +ATOM 32578 N N . THR R 1 31 ? 42.125 19.525 -9.095 1.00 108.96 ? 31 THR R N 1 +ATOM 32579 C CA . THR R 1 31 ? 41.631 18.302 -9.755 1.00 134.73 ? 31 THR R CA 1 +ATOM 32580 C C . THR R 1 31 ? 40.497 17.645 -8.969 1.00 133.54 ? 31 THR R C 1 +ATOM 32581 O O . THR R 1 31 ? 39.677 16.918 -9.531 1.00 150.97 ? 31 THR R O 1 +ATOM 32582 C CB . THR R 1 31 ? 42.760 17.261 -10.042 1.00 127.92 ? 31 THR R CB 1 +ATOM 32583 O OG1 . THR R 1 31 ? 43.504 16.976 -8.854 1.00 96.89 ? 31 THR R OG1 1 +ATOM 32584 C CG2 . THR R 1 31 ? 43.716 17.777 -11.116 1.00 146.42 ? 31 THR R CG2 1 +ATOM 32585 N N . GLY R 1 32 ? 40.507 17.844 -7.660 1.00 144.48 ? 32 GLY R N 1 +ATOM 32586 C CA . GLY R 1 32 ? 39.394 17.451 -6.804 1.00 157.48 ? 32 GLY R CA 1 +ATOM 32587 C C . GLY R 1 32 ? 39.463 18.302 -5.554 1.00 147.01 ? 32 GLY R C 1 +ATOM 32588 O O . GLY R 1 32 ? 40.548 18.738 -5.171 1.00 155.17 ? 32 GLY R O 1 +ATOM 32589 N N . LYS R 1 33 ? 38.333 18.519 -4.895 1.00 121.77 ? 33 LYS R N 1 +ATOM 32590 C CA . LYS R 1 33 ? 38.375 19.195 -3.610 1.00 114.46 ? 33 LYS R CA 1 +ATOM 32591 C C . LYS R 1 33 ? 39.127 18.357 -2.554 1.00 154.29 ? 33 LYS R C 1 +ATOM 32592 O O . LYS R 1 33 ? 39.098 17.126 -2.588 1.00 167.09 ? 33 LYS R O 1 +ATOM 32593 C CB . LYS R 1 33 ? 36.971 19.564 -3.118 1.00 102.46 ? 33 LYS R CB 1 +ATOM 32594 C CG . LYS R 1 33 ? 36.484 20.902 -3.607 1.00 93.51 ? 33 LYS R CG 1 +ATOM 32595 C CD . LYS R 1 33 ? 35.032 21.121 -3.228 1.00 83.28 ? 33 LYS R CD 1 +ATOM 32596 C CE . LYS R 1 33 ? 34.390 22.083 -4.232 1.00 79.06 ? 33 LYS R CE 1 +ATOM 32597 N NZ . LYS R 1 33 ? 32.936 22.194 -4.028 1.00 95.57 ? 33 LYS R NZ 1 +ATOM 32598 N N . ILE R 1 34 ? 39.761 19.024 -1.585 1.00 164.75 ? 34 ILE R N 1 +ATOM 32599 C CA . ILE R 1 34 ? 40.582 18.331 -0.571 1.00 139.11 ? 34 ILE R CA 1 +ATOM 32600 C C . ILE R 1 34 ? 39.973 18.420 0.808 1.00 129.57 ? 34 ILE R C 1 +ATOM 32601 O O . ILE R 1 34 ? 39.657 19.514 1.199 1.00 82.42 ? 34 ILE R O 1 +ATOM 32602 C CB . ILE R 1 34 ? 41.970 18.964 -0.462 1.00 130.16 ? 34 ILE R CB 1 +ATOM 32603 C CG1 . ILE R 1 34 ? 42.748 18.683 -1.734 1.00 119.79 ? 34 ILE R CG1 1 +ATOM 32604 C CG2 . ILE R 1 34 ? 42.738 18.394 0.715 1.00 157.84 ? 34 ILE R CG2 1 +ATOM 32605 C CD1 . ILE R 1 34 ? 43.142 19.940 -2.467 1.00 151.75 ? 34 ILE R CD1 1 +ATOM 32606 N N . PHE R 1 35 ? 39.928 17.288 1.532 1.00 121.10 ? 35 PHE R N 1 +ATOM 32607 C CA . PHE R 1 35 ? 39.166 17.162 2.781 1.00 90.39 ? 35 PHE R CA 1 +ATOM 32608 C C . PHE R 1 35 ? 39.903 17.768 3.965 1.00 63.86 ? 35 PHE R C 1 +ATOM 32609 O O . PHE R 1 35 ? 41.049 17.451 4.118 1.00 60.53 ? 35 PHE R O 1 +ATOM 32610 C CB . PHE R 1 35 ? 39.016 15.691 3.105 1.00 74.37 ? 35 PHE R CB 1 +ATOM 32611 C CG . PHE R 1 35 ? 37.817 15.044 2.506 1.00 86.24 ? 35 PHE R CG 1 +ATOM 32612 C CD1 . PHE R 1 35 ? 36.560 15.630 2.643 1.00 75.42 ? 35 PHE R CD1 1 +ATOM 32613 C CD2 . PHE R 1 35 ? 37.898 13.740 2.009 1.00 79.10 ? 35 PHE R CD2 1 +ATOM 32614 C CE1 . PHE R 1 35 ? 35.438 14.998 2.113 1.00 72.88 ? 35 PHE R CE1 1 +ATOM 32615 C CE2 . PHE R 1 35 ? 36.773 13.089 1.529 1.00 73.02 ? 35 PHE R CE2 1 +ATOM 32616 C CZ . PHE R 1 35 ? 35.546 13.730 1.551 1.00 74.63 ? 35 PHE R CZ 1 +ATOM 32617 N N . VAL R 1 36 ? 39.279 18.676 4.734 1.00 50.57 ? 36 VAL R N 1 +ATOM 32618 C CA . VAL R 1 36 ? 40.007 19.475 5.713 1.00 49.98 ? 36 VAL R CA 1 +ATOM 32619 C C . VAL R 1 36 ? 39.284 19.603 7.034 1.00 63.35 ? 36 VAL R C 1 +ATOM 32620 O O . VAL R 1 36 ? 38.076 19.503 7.099 1.00 120.72 ? 36 VAL R O 1 +ATOM 32621 C CB . VAL R 1 36 ? 40.293 20.900 5.232 1.00 54.05 ? 36 VAL R CB 1 +ATOM 32622 C CG1 . VAL R 1 36 ? 39.028 21.785 5.333 1.00 46.22 ? 36 VAL R CG1 1 +ATOM 32623 C CG2 . VAL R 1 36 ? 41.423 21.488 6.035 1.00 68.39 ? 36 VAL R CG2 1 +ATOM 32624 N N . SER R 1 37 ? 40.080 19.682 8.089 1.00 65.65 ? 37 SER R N 1 +ATOM 32625 C CA . SER R 1 37 ? 39.536 19.707 9.442 1.00 80.97 ? 37 SER R CA 1 +ATOM 32626 C C . SER R 1 37 ? 40.046 20.964 10.121 1.00 69.54 ? 37 SER R C 1 +ATOM 32627 O O . SER R 1 37 ? 41.229 21.206 10.111 1.00 50.55 ? 37 SER R O 1 +ATOM 32628 C CB . SER R 1 37 ? 40.004 18.479 10.248 1.00 81.02 ? 37 SER R CB 1 +ATOM 32629 O OG . SER R 1 37 ? 39.344 17.288 9.877 1.00 64.26 ? 37 SER R OG 1 +ATOM 32630 N N . VAL R 1 38 ? 39.149 21.730 10.727 1.00 59.92 ? 38 VAL R N 1 +ATOM 32631 C CA . VAL R 1 38 ? 39.569 22.763 11.621 1.00 63.35 ? 38 VAL R CA 1 +ATOM 32632 C C . VAL R 1 38 ? 38.988 22.499 13.007 1.00 83.10 ? 38 VAL R C 1 +ATOM 32633 O O . VAL R 1 38 ? 37.763 22.501 13.180 1.00 77.01 ? 38 VAL R O 1 +ATOM 32634 C CB . VAL R 1 38 ? 39.103 24.134 11.153 1.00 65.02 ? 38 VAL R CB 1 +ATOM 32635 C CG1 . VAL R 1 38 ? 39.549 25.178 12.144 1.00 97.31 ? 38 VAL R CG1 1 +ATOM 32636 C CG2 . VAL R 1 38 ? 39.663 24.463 9.787 1.00 81.16 ? 38 VAL R CG2 1 +ATOM 32637 N N . TYR R 1 39 ? 39.877 22.318 13.997 1.00 100.78 ? 39 TYR R N 1 +ATOM 32638 C CA . TYR R 1 39 ? 39.487 22.053 15.385 1.00 93.43 ? 39 TYR R CA 1 +ATOM 32639 C C . TYR R 1 39 ? 39.324 23.387 16.149 1.00 81.72 ? 39 TYR R C 1 +ATOM 32640 O O . TYR R 1 39 ? 38.264 23.659 16.722 1.00 75.18 ? 39 TYR R O 1 +ATOM 32641 C CB . TYR R 1 39 ? 40.507 21.101 16.070 1.00 92.31 ? 39 TYR R CB 1 +ATOM 32642 C CG . TYR R 1 39 ? 40.252 19.597 15.819 1.00 99.43 ? 39 TYR R CG 1 +ATOM 32643 C CD1 . TYR R 1 39 ? 40.539 19.021 14.609 1.00 88.14 ? 39 TYR R CD1 1 +ATOM 32644 C CD2 . TYR R 1 39 ? 39.630 18.793 16.782 1.00 111.49 ? 39 TYR R CD2 1 +ATOM 32645 C CE1 . TYR R 1 39 ? 40.195 17.696 14.352 1.00 88.64 ? 39 TYR R CE1 1 +ATOM 32646 C CE2 . TYR R 1 39 ? 39.302 17.467 16.538 1.00 79.99 ? 39 TYR R CE2 1 +ATOM 32647 C CZ . TYR R 1 39 ? 39.560 16.929 15.311 1.00 72.93 ? 39 TYR R CZ 1 +ATOM 32648 O OH . TYR R 1 39 ? 39.356 15.586 15.101 1.00 65.82 ? 39 TYR R OH 1 +ATOM 32649 N N . ASN R 1 40 ? 40.344 24.234 16.116 1.00 78.34 ? 40 ASN R N 1 +ATOM 32650 C CA . ASN R 1 40 ? 40.272 25.509 16.818 1.00 90.87 ? 40 ASN R CA 1 +ATOM 32651 C C . ASN R 1 40 ? 41.380 26.494 16.450 1.00 96.81 ? 40 ASN R C 1 +ATOM 32652 O O . ASN R 1 40 ? 42.565 26.141 16.409 1.00 129.74 ? 40 ASN R O 1 +ATOM 32653 C CB . ASN R 1 40 ? 40.336 25.258 18.319 1.00 114.80 ? 40 ASN R CB 1 +ATOM 32654 C CG . ASN R 1 40 ? 39.840 26.436 19.126 1.00 145.54 ? 40 ASN R CG 1 +ATOM 32655 O OD1 . ASN R 1 40 ? 40.601 27.056 19.873 1.00 140.81 ? 40 ASN R OD1 1 +ATOM 32656 N ND2 . ASN R 1 40 ? 38.564 26.771 18.960 1.00 173.94 ? 40 ASN R ND2 1 +ATOM 32657 N N . ILE R 1 41 ? 40.998 27.744 16.215 1.00 92.12 ? 41 ILE R N 1 +ATOM 32658 C CA . ILE R 1 41 ? 41.967 28.840 16.084 1.00 110.88 ? 41 ILE R CA 1 +ATOM 32659 C C . ILE R 1 41 ? 41.752 29.858 17.209 1.00 112.29 ? 41 ILE R C 1 +ATOM 32660 O O . ILE R 1 41 ? 40.682 30.469 17.286 1.00 140.58 ? 41 ILE R O 1 +ATOM 32661 C CB . ILE R 1 41 ? 41.850 29.555 14.713 1.00 93.33 ? 41 ILE R CB 1 +ATOM 32662 C CG1 . ILE R 1 41 ? 42.579 28.760 13.621 1.00 100.79 ? 41 ILE R CG1 1 +ATOM 32663 C CG2 . ILE R 1 41 ? 42.521 30.916 14.776 1.00 76.88 ? 41 ILE R CG2 1 +ATOM 32664 C CD1 . ILE R 1 41 ? 41.923 27.465 13.207 1.00 102.13 ? 41 ILE R CD1 1 +ATOM 32665 N N . GLN R 1 42 ? 42.750 30.023 18.080 1.00 102.15 ? 42 GLN R N 1 +ATOM 32666 C CA . GLN R 1 42 ? 42.558 30.766 19.336 1.00 113.31 ? 42 GLN R CA 1 +ATOM 32667 C C . GLN R 1 42 ? 42.850 32.240 19.196 1.00 113.52 ? 42 GLN R C 1 +ATOM 32668 O O . GLN R 1 42 ? 43.602 32.651 18.311 1.00 122.62 ? 42 GLN R O 1 +ATOM 32669 C CB . GLN R 1 42 ? 43.443 30.220 20.455 1.00 116.85 ? 42 GLN R CB 1 +ATOM 32670 C CG . GLN R 1 42 ? 43.106 28.810 20.880 1.00 122.46 ? 42 GLN R CG 1 +ATOM 32671 C CD . GLN R 1 42 ? 44.271 27.867 20.654 1.00 141.20 ? 42 GLN R CD 1 +ATOM 32672 O OE1 . GLN R 1 42 ? 45.134 27.707 21.522 1.00 156.37 ? 42 GLN R OE1 1 +ATOM 32673 N NE2 . GLN R 1 42 ? 44.311 27.238 19.480 1.00 151.52 ? 42 GLN R NE2 1 +ATOM 32674 N N . ASP R 1 43 ? 42.264 33.025 20.100 1.00 109.96 ? 43 ASP R N 1 +ATOM 32675 C CA . ASP R 1 43 ? 42.600 34.443 20.252 1.00 115.70 ? 43 ASP R CA 1 +ATOM 32676 C C . ASP R 1 43 ? 43.876 34.608 21.075 1.00 79.31 ? 43 ASP R C 1 +ATOM 32677 O O . ASP R 1 43 ? 43.824 35.121 22.189 1.00 53.68 ? 43 ASP R O 1 +ATOM 32678 C CB . ASP R 1 43 ? 41.445 35.195 20.928 1.00 127.65 ? 43 ASP R CB 1 +ATOM 32679 C CG . ASP R 1 43 ? 41.645 36.720 20.921 1.00 143.83 ? 43 ASP R CG 1 +ATOM 32680 O OD1 . ASP R 1 43 ? 41.930 37.277 19.841 1.00 129.65 ? 43 ASP R OD1 1 +ATOM 32681 O OD2 . ASP R 1 43 ? 41.489 37.373 21.981 1.00 138.63 ? 43 ASP R OD2 1 +ATOM 32682 N N . GLU R 1 44 ? 45.004 34.150 20.519 1.00 65.62 ? 44 GLU R N 1 +ATOM 32683 C CA . GLU R 1 44 ? 46.273 34.141 21.234 1.00 68.05 ? 44 GLU R CA 1 +ATOM 32684 C C . GLU R 1 44 ? 46.831 35.565 21.387 1.00 60.91 ? 44 GLU R C 1 +ATOM 32685 O O . GLU R 1 44 ? 47.993 35.751 21.794 1.00 58.79 ? 44 GLU R O 1 +ATOM 32686 C CB . GLU R 1 44 ? 47.296 33.220 20.532 1.00 79.90 ? 44 GLU R CB 1 +ATOM 32687 C CG . GLU R 1 44 ? 47.273 31.743 20.955 1.00 96.70 ? 44 GLU R CG 1 +ATOM 32688 C CD . GLU R 1 44 ? 48.301 30.849 20.229 1.00 129.86 ? 44 GLU R CD 1 +ATOM 32689 O OE1 . GLU R 1 44 ? 49.485 31.235 20.023 1.00 136.07 ? 44 GLU R OE1 1 +ATOM 32690 O OE2 . GLU R 1 44 ? 47.928 29.721 19.816 1.00 158.00 ? 44 GLU R OE2 1 +ATOM 32691 N N . THR R 1 45 ? 45.972 36.556 21.167 1.00 64.68 ? 45 THR R N 1 +ATOM 32692 C CA . THR R 1 45 ? 46.395 37.957 21.131 1.00 94.72 ? 45 THR R CA 1 +ATOM 32693 C C . THR R 1 45 ? 46.720 38.562 22.501 1.00 86.22 ? 45 THR R C 1 +ATOM 32694 O O . THR R 1 45 ? 47.660 39.324 22.638 1.00 81.68 ? 45 THR R O 1 +ATOM 32695 C CB . THR R 1 45 ? 45.375 38.845 20.370 1.00 135.47 ? 45 THR R CB 1 +ATOM 32696 O OG1 . THR R 1 45 ? 45.961 40.110 20.067 1.00 218.73 ? 45 THR R OG1 1 +ATOM 32697 C CG2 . THR R 1 45 ? 44.091 39.098 21.162 1.00 128.58 ? 45 THR R CG2 1 +ATOM 32698 N N . GLY R 1 46 ? 45.901 38.272 23.504 1.00 97.68 ? 46 GLY R N 1 +ATOM 32699 C CA . GLY R 1 46 ? 46.169 38.705 24.890 1.00 77.53 ? 46 GLY R CA 1 +ATOM 32700 C C . GLY R 1 46 ? 45.643 40.099 25.210 1.00 62.05 ? 46 GLY R C 1 +ATOM 32701 O O . GLY R 1 46 ? 46.009 40.744 26.198 1.00 100.37 ? 46 GLY R O 1 +ATOM 32702 N N . GLN R 1 47 ? 44.662 40.524 24.475 1.00 59.53 ? 47 GLN R N 1 +ATOM 32703 C CA . GLN R 1 47 ? 44.362 41.889 24.517 1.00 74.09 ? 47 GLN R CA 1 +ATOM 32704 C C . GLN R 1 47 ? 42.879 42.147 24.694 1.00 98.26 ? 47 GLN R C 1 +ATOM 32705 O O . GLN R 1 47 ? 42.004 41.454 24.096 1.00 127.97 ? 47 GLN R O 1 +ATOM 32706 C CB . GLN R 1 47 ? 44.891 42.483 23.253 1.00 91.86 ? 47 GLN R CB 1 +ATOM 32707 C CG . GLN R 1 47 ? 46.407 42.489 23.189 1.00 85.82 ? 47 GLN R CG 1 +ATOM 32708 C CD . GLN R 1 47 ? 47.041 43.078 24.411 1.00 107.71 ? 47 GLN R CD 1 +ATOM 32709 O OE1 . GLN R 1 47 ? 46.955 44.278 24.653 1.00 144.91 ? 47 GLN R OE1 1 +ATOM 32710 N NE2 . GLN R 1 47 ? 47.658 42.247 25.212 1.00 149.58 ? 47 GLN R NE2 1 +ATOM 32711 N N . PHE R 1 48 ? 42.601 43.160 25.507 1.00 73.87 ? 48 PHE R N 1 +ATOM 32712 C CA . PHE R 1 48 ? 41.228 43.590 25.758 1.00 100.84 ? 48 PHE R CA 1 +ATOM 32713 C C . PHE R 1 48 ? 41.050 45.060 25.428 1.00 95.03 ? 48 PHE R C 1 +ATOM 32714 O O . PHE R 1 48 ? 42.029 45.807 25.312 1.00 72.91 ? 48 PHE R O 1 +ATOM 32715 C CB . PHE R 1 48 ? 40.855 43.330 27.226 1.00 126.88 ? 48 PHE R CB 1 +ATOM 32716 C CG . PHE R 1 48 ? 40.794 41.891 27.570 1.00 102.65 ? 48 PHE R CG 1 +ATOM 32717 C CD1 . PHE R 1 48 ? 41.972 41.181 27.743 1.00 74.70 ? 48 PHE R CD1 1 +ATOM 32718 C CD2 . PHE R 1 48 ? 39.570 41.243 27.650 1.00 85.73 ? 48 PHE R CD2 1 +ATOM 32719 C CE1 . PHE R 1 48 ? 41.939 39.844 27.975 1.00 80.62 ? 48 PHE R CE1 1 +ATOM 32720 C CE2 . PHE R 1 48 ? 39.531 39.902 27.883 1.00 94.14 ? 48 PHE R CE2 1 +ATOM 32721 C CZ . PHE R 1 48 ? 40.717 39.202 28.055 1.00 107.48 ? 48 PHE R CZ 1 +ATOM 32722 N N . LYS R 1 49 ? 39.785 45.484 25.402 1.00 107.98 ? 49 LYS R N 1 +ATOM 32723 C CA . LYS R 1 49 ? 39.445 46.864 25.113 1.00 114.14 ? 49 LYS R CA 1 +ATOM 32724 C C . LYS R 1 49 ? 39.709 47.746 26.320 1.00 122.98 ? 49 LYS R C 1 +ATOM 32725 O O . LYS R 1 49 ? 39.535 47.315 27.471 1.00 158.61 ? 49 LYS R O 1 +ATOM 32726 C CB . LYS R 1 49 ? 37.988 46.982 24.649 1.00 100.57 ? 49 LYS R CB 1 +ATOM 32727 C CG . LYS R 1 49 ? 37.773 46.257 23.331 1.00 104.51 ? 49 LYS R CG 1 +ATOM 32728 C CD . LYS R 1 49 ? 36.439 46.484 22.649 1.00 121.32 ? 49 LYS R CD 1 +ATOM 32729 C CE . LYS R 1 49 ? 36.527 45.812 21.272 1.00 148.96 ? 49 LYS R CE 1 +ATOM 32730 N NZ . LYS R 1 49 ? 35.319 45.947 20.414 1.00 178.99 ? 49 LYS R NZ 1 +ATOM 32731 N N . PRO R 1 50 ? 40.161 48.979 26.060 1.00 119.46 ? 50 PRO R N 1 +ATOM 32732 C CA . PRO R 1 50 ? 40.406 49.954 27.106 1.00 123.85 ? 50 PRO R CA 1 +ATOM 32733 C C . PRO R 1 50 ? 39.125 50.634 27.615 1.00 112.50 ? 50 PRO R C 1 +ATOM 32734 O O . PRO R 1 50 ? 38.036 50.494 27.035 1.00 65.46 ? 50 PRO R O 1 +ATOM 32735 C CB . PRO R 1 50 ? 41.303 50.986 26.423 1.00 144.17 ? 50 PRO R CB 1 +ATOM 32736 C CG . PRO R 1 50 ? 40.895 50.923 24.992 1.00 162.64 ? 50 PRO R CG 1 +ATOM 32737 C CD . PRO R 1 50 ? 40.505 49.498 24.727 1.00 133.09 ? 50 PRO R CD 1 +ATOM 32738 N N . TYR R 1 51 ? 39.268 51.337 28.733 1.00 92.71 ? 51 TYR R N 1 +ATOM 32739 C CA . TYR R 1 51 ? 38.181 52.131 29.257 1.00 69.60 ? 51 TYR R CA 1 +ATOM 32740 C C . TYR R 1 51 ? 37.626 52.970 28.133 1.00 56.45 ? 51 TYR R C 1 +ATOM 32741 O O . TYR R 1 51 ? 38.403 53.580 27.377 1.00 72.58 ? 51 TYR R O 1 +ATOM 32742 C CB . TYR R 1 51 ? 38.682 53.024 30.409 1.00 71.96 ? 51 TYR R CB 1 +ATOM 32743 C CG . TYR R 1 51 ? 37.543 53.619 31.198 1.00 66.50 ? 51 TYR R CG 1 +ATOM 32744 C CD1 . TYR R 1 51 ? 36.994 52.919 32.260 1.00 77.87 ? 51 TYR R CD1 1 +ATOM 32745 C CD2 . TYR R 1 51 ? 37.018 54.860 30.890 1.00 71.16 ? 51 TYR R CD2 1 +ATOM 32746 C CE1 . TYR R 1 51 ? 35.937 53.418 32.990 1.00 76.41 ? 51 TYR R CE1 1 +ATOM 32747 C CE2 . TYR R 1 51 ? 35.966 55.389 31.635 1.00 88.12 ? 51 TYR R CE2 1 +ATOM 32748 C CZ . TYR R 1 51 ? 35.403 54.627 32.657 1.00 90.41 ? 51 TYR R CZ 1 +ATOM 32749 O OH . TYR R 1 51 ? 34.340 55.074 33.410 1.00 96.93 ? 51 TYR R OH 1 +ATOM 32750 N N . PRO R 1 52 ? 36.300 53.080 28.051 1.00 54.28 ? 52 PRO R N 1 +ATOM 32751 C CA . PRO R 1 52 ? 35.267 52.629 28.992 1.00 65.64 ? 52 PRO R CA 1 +ATOM 32752 C C . PRO R 1 52 ? 34.680 51.268 28.702 1.00 88.91 ? 52 PRO R C 1 +ATOM 32753 O O . PRO R 1 52 ? 33.574 50.971 29.188 1.00 78.56 ? 52 PRO R O 1 +ATOM 32754 C CB . PRO R 1 52 ? 34.166 53.681 28.837 1.00 65.10 ? 52 PRO R CB 1 +ATOM 32755 C CG . PRO R 1 52 ? 34.270 54.079 27.395 1.00 79.96 ? 52 PRO R CG 1 +ATOM 32756 C CD . PRO R 1 52 ? 35.743 53.987 27.031 1.00 69.03 ? 52 PRO R CD 1 +ATOM 32757 N N . ALA R 1 53 ? 35.361 50.441 27.900 1.00 111.50 ? 53 ALA R N 1 +ATOM 32758 C CA . ALA R 1 53 ? 34.830 49.102 27.604 1.00 125.60 ? 53 ALA R CA 1 +ATOM 32759 C C . ALA R 1 53 ? 34.743 48.311 28.899 1.00 107.02 ? 53 ALA R C 1 +ATOM 32760 O O . ALA R 1 53 ? 35.473 48.608 29.864 1.00 109.33 ? 53 ALA R O 1 +ATOM 32761 C CB . ALA R 1 53 ? 35.683 48.365 26.556 1.00 124.59 ? 53 ALA R CB 1 +ATOM 32762 N N . SER R 1 54 ? 33.895 47.287 28.915 1.00 77.65 ? 54 SER R N 1 +ATOM 32763 C CA . SER R 1 54 ? 34.009 46.322 29.986 1.00 65.54 ? 54 SER R CA 1 +ATOM 32764 C C . SER R 1 54 ? 35.421 45.731 30.029 1.00 72.04 ? 54 SER R C 1 +ATOM 32765 O O . SER R 1 54 ? 36.115 45.511 28.991 1.00 78.92 ? 54 SER R O 1 +ATOM 32766 C CB . SER R 1 54 ? 33.033 45.197 29.828 1.00 73.48 ? 54 SER R CB 1 +ATOM 32767 O OG . SER R 1 54 ? 33.425 44.032 30.570 1.00 60.88 ? 54 SER R OG 1 +ATOM 32768 N N . ASN R 1 55 ? 35.871 45.498 31.255 1.00 61.87 ? 55 ASN R N 1 +ATOM 32769 C CA . ASN R 1 55 ? 37.165 44.897 31.489 1.00 53.53 ? 55 ASN R CA 1 +ATOM 32770 C C . ASN R 1 55 ? 37.362 43.658 30.611 1.00 54.75 ? 55 ASN R C 1 +ATOM 32771 O O . ASN R 1 55 ? 38.492 43.273 30.254 1.00 39.20 ? 55 ASN R O 1 +ATOM 32772 C CB . ASN R 1 55 ? 37.260 44.541 32.962 1.00 44.15 ? 55 ASN R CB 1 +ATOM 32773 C CG . ASN R 1 55 ? 38.656 44.184 33.355 1.00 76.29 ? 55 ASN R CG 1 +ATOM 32774 O OD1 . ASN R 1 55 ? 39.651 44.602 32.735 1.00 120.59 ? 55 ASN R OD1 1 +ATOM 32775 N ND2 . ASN R 1 55 ? 38.759 43.484 34.441 1.00 101.45 ? 55 ASN R ND2 1 +ATOM 32776 N N . PHE R 1 56 ? 36.231 43.000 30.332 1.00 63.86 ? 56 PHE R N 1 +ATOM 32777 C CA . PHE R 1 56 ? 36.204 41.648 29.773 1.00 62.80 ? 56 PHE R CA 1 +ATOM 32778 C C . PHE R 1 56 ? 35.965 41.636 28.289 1.00 64.50 ? 56 PHE R C 1 +ATOM 32779 O O . PHE R 1 56 ? 35.939 40.575 27.675 1.00 83.54 ? 56 PHE R O 1 +ATOM 32780 C CB . PHE R 1 56 ? 35.078 40.817 30.388 1.00 47.41 ? 56 PHE R CB 1 +ATOM 32781 C CG . PHE R 1 56 ? 35.186 40.651 31.872 1.00 37.12 ? 56 PHE R CG 1 +ATOM 32782 C CD1 . PHE R 1 56 ? 36.288 40.039 32.468 1.00 33.64 ? 56 PHE R CD1 1 +ATOM 32783 C CD2 . PHE R 1 56 ? 34.206 41.100 32.652 1.00 39.78 ? 56 PHE R CD2 1 +ATOM 32784 C CE1 . PHE R 1 56 ? 36.382 39.889 33.824 1.00 32.02 ? 56 PHE R CE1 1 +ATOM 32785 C CE2 . PHE R 1 56 ? 34.283 40.935 34.028 1.00 46.91 ? 56 PHE R CE2 1 +ATOM 32786 C CZ . PHE R 1 56 ? 35.384 40.351 34.613 1.00 35.89 ? 56 PHE R CZ 1 +ATOM 32787 N N . SER R 1 57 ? 35.757 42.793 27.711 1.00 60.15 ? 57 SER R N 1 +ATOM 32788 C CA . SER R 1 57 ? 35.624 42.841 26.272 1.00 65.30 ? 57 SER R CA 1 +ATOM 32789 C C . SER R 1 57 ? 37.003 42.612 25.559 1.00 74.63 ? 57 SER R C 1 +ATOM 32790 O O . SER R 1 57 ? 37.952 43.386 25.671 1.00 59.67 ? 57 SER R O 1 +ATOM 32791 C CB . SER R 1 57 ? 35.003 44.172 25.874 1.00 76.38 ? 57 SER R CB 1 +ATOM 32792 O OG . SER R 1 57 ? 33.636 44.206 26.278 1.00 46.80 ? 57 SER R OG 1 +ATOM 32793 N N . THR R 1 58 ? 37.097 41.524 24.827 1.00 84.15 ? 58 THR R N 1 +ATOM 32794 C CA . THR R 1 58 ? 38.314 41.208 24.108 1.00 95.50 ? 58 THR R CA 1 +ATOM 32795 C C . THR R 1 58 ? 38.521 42.157 22.968 1.00 90.03 ? 58 THR R C 1 +ATOM 32796 O O . THR R 1 58 ? 37.573 42.620 22.341 1.00 104.14 ? 58 THR R O 1 +ATOM 32797 C CB . THR R 1 58 ? 38.233 39.789 23.530 1.00 117.89 ? 58 THR R CB 1 +ATOM 32798 O OG1 . THR R 1 58 ? 37.125 39.681 22.622 1.00 97.77 ? 58 THR R OG1 1 +ATOM 32799 C CG2 . THR R 1 58 ? 38.011 38.810 24.643 1.00 148.13 ? 58 THR R CG2 1 +ATOM 32800 N N . ALA R 1 59 ? 39.754 42.309 22.560 1.00 93.60 ? 59 ALA R N 1 +ATOM 32801 C CA . ALA R 1 59 ? 39.994 43.229 21.477 1.00 118.17 ? 59 ALA R CA 1 +ATOM 32802 C C . ALA R 1 59 ? 39.677 42.610 20.132 1.00 115.33 ? 59 ALA R C 1 +ATOM 32803 O O . ALA R 1 59 ? 39.414 43.325 19.151 1.00 172.85 ? 59 ALA R O 1 +ATOM 32804 C CB . ALA R 1 59 ? 41.420 43.689 21.490 1.00 128.27 ? 59 ALA R CB 1 +ATOM 32805 N N . VAL R 1 60 ? 39.625 41.282 20.095 1.00 97.78 ? 60 VAL R N 1 +ATOM 32806 C CA . VAL R 1 60 ? 39.424 40.538 18.842 1.00 90.68 ? 60 VAL R CA 1 +ATOM 32807 C C . VAL R 1 60 ? 38.331 39.492 19.028 1.00 105.99 ? 60 VAL R C 1 +ATOM 32808 O O . VAL R 1 60 ? 38.236 38.881 20.092 1.00 182.99 ? 60 VAL R O 1 +ATOM 32809 C CB . VAL R 1 60 ? 40.724 39.825 18.464 1.00 72.89 ? 60 VAL R CB 1 +ATOM 32810 C CG1 . VAL R 1 60 ? 40.569 39.029 17.196 1.00 56.78 ? 60 VAL R CG1 1 +ATOM 32811 C CG2 . VAL R 1 60 ? 41.844 40.847 18.346 1.00 97.90 ? 60 VAL R CG2 1 +ATOM 32812 N N . PRO R 1 61 ? 37.446 39.336 18.030 1.00 117.63 ? 61 PRO R N 1 +ATOM 32813 C CA . PRO R 1 61 ? 36.397 38.345 18.197 1.00 133.24 ? 61 PRO R CA 1 +ATOM 32814 C C . PRO R 1 61 ? 36.967 36.923 18.329 1.00 140.21 ? 61 PRO R C 1 +ATOM 32815 O O . PRO R 1 61 ? 37.947 36.579 17.658 1.00 143.30 ? 61 PRO R O 1 +ATOM 32816 C CB . PRO R 1 61 ? 35.557 38.503 16.923 1.00 121.31 ? 61 PRO R CB 1 +ATOM 32817 C CG . PRO R 1 61 ? 36.462 39.157 15.942 1.00 99.98 ? 61 PRO R CG 1 +ATOM 32818 C CD . PRO R 1 61 ? 37.319 40.057 16.757 1.00 102.82 ? 61 PRO R CD 1 +ATOM 32819 N N . GLN R 1 62 ? 36.296 36.100 19.136 1.00 117.22 ? 62 GLN R N 1 +ATOM 32820 C CA . GLN R 1 62 ? 36.752 34.744 19.409 1.00 115.36 ? 62 GLN R CA 1 +ATOM 32821 C C . GLN R 1 62 ? 36.292 33.738 18.367 1.00 124.90 ? 62 GLN R C 1 +ATOM 32822 O O . GLN R 1 62 ? 35.929 32.622 18.702 1.00 101.72 ? 62 GLN R O 1 +ATOM 32823 C CB . GLN R 1 62 ? 36.241 34.314 20.791 1.00 128.82 ? 62 GLN R CB 1 +ATOM 32824 C CG . GLN R 1 62 ? 36.522 35.310 21.898 1.00 128.55 ? 62 GLN R CG 1 +ATOM 32825 C CD . GLN R 1 62 ? 38.006 35.589 22.017 1.00 127.58 ? 62 GLN R CD 1 +ATOM 32826 O OE1 . GLN R 1 62 ? 38.751 34.804 22.593 1.00 150.15 ? 62 GLN R OE1 1 +ATOM 32827 N NE2 . GLN R 1 62 ? 38.443 36.693 21.460 1.00 146.76 ? 62 GLN R NE2 1 +ATOM 32828 N N . SER R 1 63 ? 36.187 34.178 17.120 1.00 145.25 ? 63 SER R N 1 +ATOM 32829 C CA . SER R 1 63 ? 35.330 33.508 16.135 1.00 149.30 ? 63 SER R CA 1 +ATOM 32830 C C . SER R 1 63 ? 36.141 33.058 14.927 1.00 127.85 ? 63 SER R C 1 +ATOM 32831 O O . SER R 1 63 ? 35.583 32.628 13.916 1.00 112.63 ? 63 SER R O 1 +ATOM 32832 C CB . SER R 1 63 ? 34.155 34.431 15.707 1.00 141.86 ? 63 SER R CB 1 +ATOM 32833 O OG . SER R 1 63 ? 34.580 35.638 15.081 1.00 110.53 ? 63 SER R OG 1 +ATOM 32834 N N . ALA R 1 64 ? 37.457 33.187 15.048 1.00 99.14 ? 64 ALA R N 1 +ATOM 32835 C CA . ALA R 1 64 ? 38.371 32.953 13.940 1.00 86.58 ? 64 ALA R CA 1 +ATOM 32836 C C . ALA R 1 64 ? 38.222 31.565 13.315 1.00 88.13 ? 64 ALA R C 1 +ATOM 32837 O O . ALA R 1 64 ? 38.257 31.412 12.087 1.00 129.98 ? 64 ALA R O 1 +ATOM 32838 C CB . ALA R 1 64 ? 39.781 33.143 14.425 1.00 94.90 ? 64 ALA R CB 1 +ATOM 32839 N N . THR R 1 65 ? 37.942 30.579 14.156 1.00 99.59 ? 65 THR R N 1 +ATOM 32840 C CA . THR R 1 65 ? 37.747 29.204 13.727 1.00 100.35 ? 65 THR R CA 1 +ATOM 32841 C C . THR R 1 65 ? 36.682 29.061 12.654 1.00 102.87 ? 65 THR R C 1 +ATOM 32842 O O . THR R 1 65 ? 36.919 28.453 11.593 1.00 126.99 ? 65 THR R O 1 +ATOM 32843 C CB . THR R 1 65 ? 37.276 28.359 14.904 1.00 121.55 ? 65 THR R CB 1 +ATOM 32844 O OG1 . THR R 1 65 ? 37.976 28.779 16.077 1.00 159.68 ? 65 THR R OG1 1 +ATOM 32845 C CG2 . THR R 1 65 ? 37.522 26.872 14.637 1.00 138.74 ? 65 THR R CG2 1 +ATOM 32846 N N . ALA R 1 66 ? 35.519 29.651 12.907 1.00 79.25 ? 66 ALA R N 1 +ATOM 32847 C CA . ALA R 1 66 ? 34.425 29.540 11.969 1.00 87.92 ? 66 ALA R CA 1 +ATOM 32848 C C . ALA R 1 66 ? 34.701 30.322 10.674 1.00 84.56 ? 66 ALA R C 1 +ATOM 32849 O O . ALA R 1 66 ? 34.307 29.903 9.564 1.00 86.40 ? 66 ALA R O 1 +ATOM 32850 C CB . ALA R 1 66 ? 33.149 30.019 12.622 1.00 113.26 ? 66 ALA R CB 1 +ATOM 32851 N N . MET R 1 67 ? 35.396 31.450 10.810 1.00 82.42 ? 67 MET R N 1 +ATOM 32852 C CA . MET R 1 67 ? 35.807 32.251 9.641 1.00 102.86 ? 67 MET R CA 1 +ATOM 32853 C C . MET R 1 67 ? 36.751 31.461 8.717 1.00 80.06 ? 67 MET R C 1 +ATOM 32854 O O . MET R 1 67 ? 36.610 31.498 7.495 1.00 63.05 ? 67 MET R O 1 +ATOM 32855 C CB . MET R 1 67 ? 36.503 33.561 10.074 1.00 115.93 ? 67 MET R CB 1 +ATOM 32856 C CG . MET R 1 67 ? 35.601 34.596 10.740 1.00 124.82 ? 67 MET R CG 1 +ATOM 32857 S SD . MET R 1 67 ? 36.569 35.920 11.510 1.00 113.09 ? 67 MET R SD 1 +ATOM 32858 C CE . MET R 1 67 ? 35.269 37.044 12.039 1.00 113.62 ? 67 MET R CE 1 +ATOM 32859 N N . LEU R 1 68 ? 37.704 30.761 9.321 1.00 77.90 ? 68 LEU R N 1 +ATOM 32860 C CA . LEU R 1 68 ? 38.634 29.962 8.568 1.00 78.24 ? 68 LEU R CA 1 +ATOM 32861 C C . LEU R 1 68 ? 37.923 28.842 7.848 1.00 88.36 ? 68 LEU R C 1 +ATOM 32862 O O . LEU R 1 68 ? 38.181 28.609 6.679 1.00 79.65 ? 68 LEU R O 1 +ATOM 32863 C CB . LEU R 1 68 ? 39.697 29.355 9.468 1.00 100.35 ? 68 LEU R CB 1 +ATOM 32864 C CG . LEU R 1 68 ? 40.572 28.312 8.741 1.00 121.93 ? 68 LEU R CG 1 +ATOM 32865 C CD1 . LEU R 1 68 ? 41.400 28.982 7.655 1.00 141.57 ? 68 LEU R CD1 1 +ATOM 32866 C CD2 . LEU R 1 68 ? 41.478 27.549 9.692 1.00 112.26 ? 68 LEU R CD2 1 +ATOM 32867 N N . VAL R 1 69 ? 37.026 28.136 8.542 1.00 127.31 ? 69 VAL R N 1 +ATOM 32868 C CA . VAL R 1 69 ? 36.255 27.052 7.905 1.00 127.56 ? 69 VAL R CA 1 +ATOM 32869 C C . VAL R 1 69 ? 35.460 27.593 6.709 1.00 124.86 ? 69 VAL R C 1 +ATOM 32870 O O . VAL R 1 69 ? 35.439 27.001 5.625 1.00 111.79 ? 69 VAL R O 1 +ATOM 32871 C CB . VAL R 1 69 ? 35.273 26.354 8.879 1.00 120.15 ? 69 VAL R CB 1 +ATOM 32872 C CG1 . VAL R 1 69 ? 34.428 25.356 8.121 1.00 102.90 ? 69 VAL R CG1 1 +ATOM 32873 C CG2 . VAL R 1 69 ? 36.005 25.644 10.010 1.00 107.60 ? 69 VAL R CG2 1 +ATOM 32874 N N . THR R 1 70 ? 34.830 28.746 6.912 1.00 116.36 ? 70 THR R N 1 +ATOM 32875 C CA . THR R 1 70 ? 34.059 29.395 5.863 1.00 105.28 ? 70 THR R CA 1 +ATOM 32876 C C . THR R 1 70 ? 34.938 29.790 4.677 1.00 91.65 ? 70 THR R C 1 +ATOM 32877 O O . THR R 1 70 ? 34.584 29.546 3.509 1.00 110.32 ? 70 THR R O 1 +ATOM 32878 C CB . THR R 1 70 ? 33.322 30.628 6.406 1.00 92.70 ? 70 THR R CB 1 +ATOM 32879 O OG1 . THR R 1 70 ? 32.520 30.217 7.524 1.00 80.53 ? 70 THR R OG1 1 +ATOM 32880 C CG2 . THR R 1 70 ? 32.427 31.257 5.315 1.00 96.46 ? 70 THR R CG2 1 +ATOM 32881 N N . ALA R 1 71 ? 36.087 30.373 4.971 1.00 79.81 ? 71 ALA R N 1 +ATOM 32882 C CA . ALA R 1 71 ? 37.020 30.725 3.906 1.00 112.76 ? 71 ALA R CA 1 +ATOM 32883 C C . ALA R 1 71 ? 37.488 29.482 3.136 1.00 103.52 ? 71 ALA R C 1 +ATOM 32884 O O . ALA R 1 71 ? 37.617 29.506 1.902 1.00 94.32 ? 71 ALA R O 1 +ATOM 32885 C CB . ALA R 1 71 ? 38.214 31.490 4.479 1.00 124.39 ? 71 ALA R CB 1 +ATOM 32886 N N . LEU R 1 72 ? 37.771 28.417 3.876 1.00 107.05 ? 72 LEU R N 1 +ATOM 32887 C CA . LEU R 1 72 ? 38.209 27.154 3.268 1.00 118.25 ? 72 LEU R CA 1 +ATOM 32888 C C . LEU R 1 72 ? 37.132 26.577 2.368 1.00 105.45 ? 72 LEU R C 1 +ATOM 32889 O O . LEU R 1 72 ? 37.445 25.890 1.404 1.00 104.91 ? 72 LEU R O 1 +ATOM 32890 C CB . LEU R 1 72 ? 38.567 26.113 4.340 1.00 101.74 ? 72 LEU R CB 1 +ATOM 32891 C CG . LEU R 1 72 ? 39.814 26.415 5.167 1.00 86.60 ? 72 LEU R CG 1 +ATOM 32892 C CD1 . LEU R 1 72 ? 39.799 25.579 6.398 1.00 65.81 ? 72 LEU R CD1 1 +ATOM 32893 C CD2 . LEU R 1 72 ? 41.081 26.170 4.377 1.00 112.03 ? 72 LEU R CD2 1 +ATOM 32894 N N . LYS R 1 73 ? 35.881 26.923 2.642 1.00 85.60 ? 73 LYS R N 1 +ATOM 32895 C CA . LYS R 1 73 ? 34.805 26.452 1.798 1.00 96.29 ? 73 LYS R CA 1 +ATOM 32896 C C . LYS R 1 73 ? 34.678 27.350 0.562 1.00 102.24 ? 73 LYS R C 1 +ATOM 32897 O O . LYS R 1 73 ? 34.444 26.856 -0.544 1.00 137.24 ? 73 LYS R O 1 +ATOM 32898 C CB . LYS R 1 73 ? 33.464 26.389 2.545 1.00 108.43 ? 73 LYS R CB 1 +ATOM 32899 C CG . LYS R 1 73 ? 32.367 25.613 1.790 1.00 101.09 ? 73 LYS R CG 1 +ATOM 32900 C CD . LYS R 1 73 ? 31.042 25.546 2.565 1.00 95.27 ? 73 LYS R CD 1 +ATOM 32901 C CE . LYS R 1 73 ? 29.849 25.393 1.632 1.00 79.21 ? 73 LYS R CE 1 +ATOM 32902 N NZ . LYS R 1 73 ? 29.180 24.070 1.747 1.00 60.84 ? 73 LYS R NZ 1 +ATOM 32903 N N . ASP R 1 74 ? 34.673 28.665 0.770 1.00 101.15 ? 74 ASP R N 1 +ATOM 32904 C CA . ASP R 1 74 ? 34.365 29.615 -0.312 1.00 106.01 ? 74 ASP R CA 1 +ATOM 32905 C C . ASP R 1 74 ? 35.386 29.460 -1.428 1.00 93.42 ? 74 ASP R C 1 +ATOM 32906 O O . ASP R 1 74 ? 35.088 29.761 -2.590 1.00 117.75 ? 74 ASP R O 1 +ATOM 32907 C CB . ASP R 1 74 ? 34.340 31.067 0.210 1.00 95.07 ? 74 ASP R CB 1 +ATOM 32908 C CG . ASP R 1 74 ? 33.122 31.379 1.097 1.00 76.88 ? 74 ASP R CG 1 +ATOM 32909 O OD1 . ASP R 1 74 ? 32.045 30.739 0.958 1.00 41.34 ? 74 ASP R OD1 1 +ATOM 32910 O OD2 . ASP R 1 74 ? 33.287 32.235 1.997 1.00 78.57 ? 74 ASP R OD2 1 +ATOM 32911 N N . SER R 1 75 ? 36.581 28.997 -1.067 1.00 83.81 ? 75 SER R N 1 +ATOM 32912 C CA . SER R 1 75 ? 37.686 28.889 -2.026 1.00 124.94 ? 75 SER R CA 1 +ATOM 32913 C C . SER R 1 75 ? 37.424 27.858 -3.113 1.00 124.78 ? 75 SER R C 1 +ATOM 32914 O O . SER R 1 75 ? 37.997 27.926 -4.202 1.00 108.85 ? 75 SER R O 1 +ATOM 32915 C CB . SER R 1 75 ? 38.985 28.524 -1.307 1.00 145.34 ? 75 SER R CB 1 +ATOM 32916 O OG . SER R 1 75 ? 39.094 27.124 -1.123 1.00 131.26 ? 75 SER R OG 1 +ATOM 32917 N N . ARG R 1 76 ? 36.553 26.911 -2.792 1.00 126.57 ? 76 ARG R N 1 +ATOM 32918 C CA . ARG R 1 76 ? 36.220 25.808 -3.676 1.00 142.57 ? 76 ARG R CA 1 +ATOM 32919 C C . ARG R 1 76 ? 37.451 24.978 -3.973 1.00 114.72 ? 76 ARG R C 1 +ATOM 32920 O O . ARG R 1 76 ? 37.587 24.414 -5.055 1.00 90.04 ? 76 ARG R O 1 +ATOM 32921 C CB . ARG R 1 76 ? 35.587 26.302 -4.971 1.00 156.89 ? 76 ARG R CB 1 +ATOM 32922 C CG . ARG R 1 76 ? 34.284 27.075 -4.785 1.00 130.25 ? 76 ARG R CG 1 +ATOM 32923 C CD . ARG R 1 76 ? 33.738 27.484 -6.139 1.00 147.79 ? 76 ARG R CD 1 +ATOM 32924 N NE . ARG R 1 76 ? 34.592 28.508 -6.755 1.00 153.84 ? 76 ARG R NE 1 +ATOM 32925 C CZ . ARG R 1 76 ? 35.567 28.273 -7.641 1.00 156.87 ? 76 ARG R CZ 1 +ATOM 32926 N NH1 . ARG R 1 76 ? 35.859 27.027 -8.040 1.00 159.99 ? 76 ARG R NH1 1 +ATOM 32927 N NH2 . ARG R 1 76 ? 36.264 29.294 -8.119 1.00 124.71 ? 76 ARG R NH2 1 +ATOM 32928 N N . TRP R 1 77 ? 38.295 24.848 -2.957 1.00 128.41 ? 77 TRP R N 1 +ATOM 32929 C CA . TRP R 1 77 ? 39.397 23.885 -2.948 1.00 148.99 ? 77 TRP R CA 1 +ATOM 32930 C C . TRP R 1 77 ? 39.216 22.777 -1.861 1.00 146.12 ? 77 TRP R C 1 +ATOM 32931 O O . TRP R 1 77 ? 39.591 21.614 -2.076 1.00 95.50 ? 77 TRP R O 1 +ATOM 32932 C CB . TRP R 1 77 ? 40.696 24.640 -2.677 1.00 141.75 ? 77 TRP R CB 1 +ATOM 32933 C CG . TRP R 1 77 ? 41.398 25.133 -3.859 1.00 108.15 ? 77 TRP R CG 1 +ATOM 32934 C CD1 . TRP R 1 77 ? 41.064 26.203 -4.619 1.00 94.11 ? 77 TRP R CD1 1 +ATOM 32935 C CD2 . TRP R 1 77 ? 42.573 24.564 -4.439 1.00 93.48 ? 77 TRP R CD2 1 +ATOM 32936 N NE1 . TRP R 1 77 ? 41.945 26.321 -5.654 1.00 124.34 ? 77 TRP R NE1 1 +ATOM 32937 C CE2 . TRP R 1 77 ? 42.897 25.338 -5.549 1.00 98.38 ? 77 TRP R CE2 1 +ATOM 32938 C CE3 . TRP R 1 77 ? 43.384 23.471 -4.122 1.00 100.26 ? 77 TRP R CE3 1 +ATOM 32939 C CZ2 . TRP R 1 77 ? 43.999 25.057 -6.362 1.00 104.01 ? 77 TRP R CZ2 1 +ATOM 32940 C CZ3 . TRP R 1 77 ? 44.476 23.191 -4.931 1.00 100.08 ? 77 TRP R CZ3 1 +ATOM 32941 C CH2 . TRP R 1 77 ? 44.772 23.981 -6.034 1.00 101.08 ? 77 TRP R CH2 1 +ATOM 32942 N N . PHE R 1 78 ? 38.531 23.118 -0.774 1.00 143.58 ? 78 PHE R N 1 +ATOM 32943 C CA . PHE R 1 78 ? 38.362 22.226 0.376 1.00 131.20 ? 78 PHE R CA 1 +ATOM 32944 C C . PHE R 1 78 ? 36.883 22.005 0.619 1.00 143.65 ? 78 PHE R C 1 +ATOM 32945 O O . PHE R 1 78 ? 36.111 22.904 0.671 1.00 138.95 ? 78 PHE R O 1 +ATOM 32946 C CB . PHE R 1 78 ? 39.032 22.878 1.584 1.00 132.88 ? 78 PHE R CB 1 +ATOM 32947 C CG . PHE R 1 78 ? 40.479 23.257 1.342 1.00 120.83 ? 78 PHE R CG 1 +ATOM 32948 C CD1 . PHE R 1 78 ? 41.485 22.276 1.299 1.00 92.52 ? 78 PHE R CD1 1 +ATOM 32949 C CD2 . PHE R 1 78 ? 40.837 24.602 1.188 1.00 94.48 ? 78 PHE R CD2 1 +ATOM 32950 C CE1 . PHE R 1 78 ? 42.807 22.639 1.159 1.00 81.88 ? 78 PHE R CE1 1 +ATOM 32951 C CE2 . PHE R 1 78 ? 42.164 24.972 1.046 1.00 80.89 ? 78 PHE R CE2 1 +ATOM 32952 C CZ . PHE R 1 78 ? 43.146 23.984 1.017 1.00 91.23 ? 78 PHE R CZ 1 +ATOM 32953 N N . ILE R 1 79 ? 36.491 20.756 0.648 1.00 151.66 ? 79 ILE R N 1 +ATOM 32954 C CA . ILE R 1 79 ? 35.344 20.430 1.503 1.00 132.50 ? 79 ILE R CA 1 +ATOM 32955 C C . ILE R 1 79 ? 35.949 20.618 2.821 1.00 135.42 ? 79 ILE R C 1 +ATOM 32956 O O . ILE R 1 79 ? 36.986 20.017 3.075 1.00 114.71 ? 79 ILE R O 1 +ATOM 32957 C CB . ILE R 1 79 ? 34.952 18.949 1.399 1.00 113.55 ? 79 ILE R CB 1 +ATOM 32958 C CG1 . ILE R 1 79 ? 34.824 18.643 -0.101 1.00 150.73 ? 79 ILE R CG1 1 +ATOM 32959 C CG2 . ILE R 1 79 ? 33.669 18.700 2.162 1.00 115.05 ? 79 ILE R CG2 1 +ATOM 32960 C CD1 . ILE R 1 79 ? 34.960 17.213 -0.468 1.00 137.00 ? 79 ILE R CD1 1 +ATOM 32961 N N . PRO R 1 80 ? 35.320 21.447 3.691 1.00 170.42 ? 80 PRO R N 1 +ATOM 32962 C CA . PRO R 1 80 ? 35.832 21.386 5.036 1.00 156.63 ? 80 PRO R CA 1 +ATOM 32963 C C . PRO R 1 80 ? 35.098 20.432 5.806 1.00 124.14 ? 80 PRO R C 1 +ATOM 32964 O O . PRO R 1 80 ? 33.903 20.630 6.198 1.00 111.09 ? 80 PRO R O 1 +ATOM 32965 C CB . PRO R 1 80 ? 35.442 22.685 5.675 1.00 160.42 ? 80 PRO R CB 1 +ATOM 32966 C CG . PRO R 1 80 ? 35.245 23.591 4.480 1.00 218.24 ? 80 PRO R CG 1 +ATOM 32967 C CD . PRO R 1 80 ? 34.554 22.677 3.537 1.00 215.30 ? 80 PRO R CD 1 +ATOM 32968 N N . LEU R 1 81 ? 35.818 19.394 6.097 1.00 106.84 ? 81 LEU R N 1 +ATOM 32969 C CA . LEU R 1 81 ? 35.325 18.605 7.199 1.00 93.42 ? 81 LEU R CA 1 +ATOM 32970 C C . LEU R 1 81 ? 35.455 19.282 8.527 1.00 86.87 ? 81 LEU R C 1 +ATOM 32971 O O . LEU R 1 81 ? 36.572 19.729 8.944 1.00 79.68 ? 81 LEU R O 1 +ATOM 32972 C CB . LEU R 1 81 ? 35.996 17.257 7.290 1.00 119.76 ? 81 LEU R CB 1 +ATOM 32973 C CG . LEU R 1 81 ? 35.568 16.160 6.271 1.00 140.43 ? 81 LEU R CG 1 +ATOM 32974 C CD1 . LEU R 1 81 ? 36.383 14.906 6.532 1.00 98.97 ? 81 LEU R CD1 1 +ATOM 32975 C CD2 . LEU R 1 81 ? 34.068 15.928 6.410 1.00 174.83 ? 81 LEU R CD2 1 +ATOM 32976 N N . GLU R 1 82 ? 34.267 19.146 9.195 1.00 92.84 ? 82 GLU R N 1 +ATOM 32977 C CA . GLU R 1 82 ? 33.687 19.633 10.540 1.00 123.67 ? 82 GLU R CA 1 +ATOM 32978 C C . GLU R 1 82 ? 33.976 18.775 11.827 1.00 107.03 ? 82 GLU R C 1 +ATOM 32979 O O . GLU R 1 82 ? 33.604 17.596 11.860 1.00 88.14 ? 82 GLU R O 1 +ATOM 32980 C CB . GLU R 1 82 ? 32.112 19.729 10.457 1.00 114.41 ? 82 GLU R CB 1 +ATOM 32981 C CG . GLU R 1 82 ? 31.392 20.174 11.760 1.00 127.58 ? 82 GLU R CG 1 +ATOM 32982 C CD . GLU R 1 82 ? 31.608 21.650 12.173 1.00 117.09 ? 82 GLU R CD 1 +ATOM 32983 O OE1 . GLU R 1 82 ? 32.729 22.183 12.134 1.00 125.23 ? 82 GLU R OE1 1 +ATOM 32984 O OE2 . GLU R 1 82 ? 30.635 22.301 12.598 1.00 64.15 ? 82 GLU R OE2 1 +ATOM 32985 N N . ARG R 1 83 ? 34.429 19.511 12.873 1.00 104.92 ? 83 ARG R N 1 +ATOM 32986 C CA . ARG R 1 83 ? 35.000 19.107 14.200 1.00 97.86 ? 83 ARG R CA 1 +ATOM 32987 C C . ARG R 1 83 ? 34.792 20.158 15.356 1.00 87.97 ? 83 ARG R C 1 +ATOM 32988 O O . ARG R 1 83 ? 34.953 19.825 16.551 1.00 102.07 ? 83 ARG R O 1 +ATOM 32989 C CB . ARG R 1 83 ? 36.513 18.858 14.011 1.00 103.39 ? 83 ARG R CB 1 +ATOM 32990 C CG . ARG R 1 83 ? 36.792 17.861 12.920 1.00 87.70 ? 83 ARG R CG 1 +ATOM 32991 C CD . ARG R 1 83 ? 36.385 16.480 13.324 1.00 92.41 ? 83 ARG R CD 1 +ATOM 32992 N NE . ARG R 1 83 ? 36.880 15.570 12.307 1.00 97.03 ? 83 ARG R NE 1 +ATOM 32993 C CZ . ARG R 1 83 ? 36.152 15.010 11.332 1.00 119.96 ? 83 ARG R CZ 1 +ATOM 32994 N NH1 . ARG R 1 83 ? 34.834 15.193 11.228 1.00 91.21 ? 83 ARG R NH1 1 +ATOM 32995 N NH2 . ARG R 1 83 ? 36.769 14.199 10.469 1.00 162.73 ? 83 ARG R NH2 1 +ATOM 32996 N N . GLN R 1 84 ? 34.448 21.413 15.048 1.00 82.32 ? 84 GLN R N 1 +ATOM 32997 C CA . GLN R 1 84 ? 34.253 22.411 16.130 1.00 99.97 ? 84 GLN R CA 1 +ATOM 32998 C C . GLN R 1 84 ? 33.139 21.973 17.059 1.00 96.04 ? 84 GLN R C 1 +ATOM 32999 O O . GLN R 1 84 ? 33.276 22.034 18.262 1.00 122.06 ? 84 GLN R O 1 +ATOM 33000 C CB . GLN R 1 84 ? 33.984 23.838 15.616 1.00 84.90 ? 84 GLN R CB 1 +ATOM 33001 C CG . GLN R 1 84 ? 34.496 24.965 16.523 1.00 66.64 ? 84 GLN R CG 1 +ATOM 33002 C CD . GLN R 1 84 ? 34.118 26.332 16.010 1.00 73.10 ? 84 GLN R CD 1 +ATOM 33003 O OE1 . GLN R 1 84 ? 34.113 26.591 14.796 1.00 101.61 ? 84 GLN R OE1 1 +ATOM 33004 N NE2 . GLN R 1 84 ? 33.821 27.234 16.920 1.00 96.64 ? 84 GLN R NE2 1 +ATOM 33005 N N . GLY R 1 85 ? 32.093 21.388 16.519 1.00 132.90 ? 85 GLY R N 1 +ATOM 33006 C CA . GLY R 1 85 ? 31.040 20.856 17.391 1.00 150.90 ? 85 GLY R CA 1 +ATOM 33007 C C . GLY R 1 85 ? 30.964 19.343 17.424 1.00 138.64 ? 85 GLY R C 1 +ATOM 33008 O O . GLY R 1 85 ? 29.868 18.788 17.405 1.00 142.41 ? 85 GLY R O 1 +ATOM 33009 N N . LEU R 1 86 ? 32.118 18.664 17.451 1.00 110.22 ? 86 LEU R N 1 +ATOM 33010 C CA . LEU R 1 86 ? 32.167 17.205 17.176 1.00 84.93 ? 86 LEU R CA 1 +ATOM 33011 C C . LEU R 1 86 ? 31.340 16.413 18.181 1.00 88.73 ? 86 LEU R C 1 +ATOM 33012 O O . LEU R 1 86 ? 30.690 15.427 17.827 1.00 70.89 ? 86 LEU R O 1 +ATOM 33013 C CB . LEU R 1 86 ? 33.598 16.672 17.201 1.00 79.01 ? 86 LEU R CB 1 +ATOM 33014 C CG . LEU R 1 86 ? 33.870 15.143 17.146 1.00 60.41 ? 86 LEU R CG 1 +ATOM 33015 C CD1 . LEU R 1 86 ? 33.346 14.516 15.881 1.00 56.39 ? 86 LEU R CD1 1 +ATOM 33016 C CD2 . LEU R 1 86 ? 35.363 14.895 17.245 1.00 66.84 ? 86 LEU R CD2 1 +ATOM 33017 N N . GLN R 1 87 ? 31.301 16.899 19.413 1.00 96.09 ? 87 GLN R N 1 +ATOM 33018 C CA . GLN R 1 87 ? 30.583 16.186 20.461 1.00 105.70 ? 87 GLN R CA 1 +ATOM 33019 C C . GLN R 1 87 ? 29.068 16.025 20.143 1.00 108.31 ? 87 GLN R C 1 +ATOM 33020 O O . GLN R 1 87 ? 28.478 14.947 20.323 1.00 143.79 ? 87 GLN R O 1 +ATOM 33021 C CB . GLN R 1 87 ? 30.811 16.886 21.805 1.00 109.91 ? 87 GLN R CB 1 +ATOM 33022 C CG . GLN R 1 87 ? 30.886 15.928 22.980 1.00 118.10 ? 87 GLN R CG 1 +ATOM 33023 C CD . GLN R 1 87 ? 31.704 14.672 22.677 1.00 137.66 ? 87 GLN R CD 1 +ATOM 33024 O OE1 . GLN R 1 87 ? 32.891 14.748 22.341 1.00 156.10 ? 87 GLN R OE1 1 +ATOM 33025 N NE2 . GLN R 1 87 ? 31.089 13.505 22.857 1.00 150.77 ? 87 GLN R NE2 1 +ATOM 33026 N N . ASN R 1 88 ? 28.440 17.103 19.676 1.00 79.40 ? 88 ASN R N 1 +ATOM 33027 C CA . ASN R 1 88 ? 27.023 17.084 19.348 1.00 49.16 ? 88 ASN R CA 1 +ATOM 33028 C C . ASN R 1 88 ? 26.802 16.136 18.208 1.00 47.77 ? 88 ASN R C 1 +ATOM 33029 O O . ASN R 1 88 ? 25.729 15.531 18.063 1.00 63.18 ? 88 ASN R O 1 +ATOM 33030 C CB . ASN R 1 88 ? 26.559 18.466 18.924 1.00 62.38 ? 88 ASN R CB 1 +ATOM 33031 C CG . ASN R 1 88 ? 26.741 19.488 19.988 1.00 74.91 ? 88 ASN R CG 1 +ATOM 33032 O OD1 . ASN R 1 88 ? 26.651 19.158 21.169 1.00 73.92 ? 88 ASN R OD1 1 +ATOM 33033 N ND2 . ASN R 1 88 ? 27.142 20.721 19.592 1.00 84.89 ? 88 ASN R ND2 1 +ATOM 33034 N N . LEU R 1 89 ? 27.765 16.089 17.298 1.00 59.41 ? 89 LEU R N 1 +ATOM 33035 C CA . LEU R 1 89 ? 27.618 15.316 16.063 1.00 95.79 ? 89 LEU R CA 1 +ATOM 33036 C C . LEU R 1 89 ? 27.553 13.834 16.470 1.00 99.23 ? 89 LEU R C 1 +ATOM 33037 O O . LEU R 1 89 ? 26.695 13.065 15.994 1.00 79.88 ? 89 LEU R O 1 +ATOM 33038 C CB . LEU R 1 89 ? 28.811 15.606 15.125 1.00 96.67 ? 89 LEU R CB 1 +ATOM 33039 C CG . LEU R 1 89 ? 28.662 15.468 13.609 1.00 84.91 ? 89 LEU R CG 1 +ATOM 33040 C CD1 . LEU R 1 89 ? 29.526 14.327 13.122 1.00 81.84 ? 89 LEU R CD1 1 +ATOM 33041 C CD2 . LEU R 1 89 ? 27.219 15.220 13.200 1.00 88.74 ? 89 LEU R CD2 1 +ATOM 33042 N N . LEU R 1 90 ? 28.407 13.482 17.420 1.00 85.41 ? 90 LEU R N 1 +ATOM 33043 C CA . LEU R 1 90 ? 28.471 12.106 17.893 1.00 89.03 ? 90 LEU R CA 1 +ATOM 33044 C C . LEU R 1 90 ? 27.208 11.743 18.698 1.00 96.70 ? 90 LEU R C 1 +ATOM 33045 O O . LEU R 1 90 ? 26.773 10.594 18.710 1.00 99.06 ? 90 LEU R O 1 +ATOM 33046 C CB . LEU R 1 90 ? 29.720 11.917 18.745 1.00 83.91 ? 90 LEU R CB 1 +ATOM 33047 C CG . LEU R 1 90 ? 31.027 12.195 18.037 1.00 73.95 ? 90 LEU R CG 1 +ATOM 33048 C CD1 . LEU R 1 90 ? 32.134 12.438 19.038 1.00 66.96 ? 90 LEU R CD1 1 +ATOM 33049 C CD2 . LEU R 1 90 ? 31.333 11.021 17.126 1.00 93.25 ? 90 LEU R CD2 1 +ATOM 33050 N N . ASN R 1 91 ? 26.633 12.740 19.369 1.00 77.82 ? 91 ASN R N 1 +ATOM 33051 C CA . ASN R 1 91 ? 25.407 12.554 20.109 1.00 63.26 ? 91 ASN R CA 1 +ATOM 33052 C C . ASN R 1 91 ? 24.224 12.295 19.226 1.00 69.80 ? 91 ASN R C 1 +ATOM 33053 O O . ASN R 1 91 ? 23.477 11.354 19.453 1.00 93.88 ? 91 ASN R O 1 +ATOM 33054 C CB . ASN R 1 91 ? 25.128 13.749 20.976 1.00 85.88 ? 91 ASN R CB 1 +ATOM 33055 C CG . ASN R 1 91 ? 24.872 13.319 22.394 1.00 130.56 ? 91 ASN R CG 1 +ATOM 33056 O OD1 . ASN R 1 91 ? 25.735 12.653 22.974 1.00 185.39 ? 91 ASN R OD1 1 +ATOM 33057 N ND2 . ASN R 1 91 ? 23.664 13.569 22.924 1.00 132.28 ? 91 ASN R ND2 1 +ATOM 33058 N N . GLU R 1 92 ? 24.057 13.116 18.186 1.00 96.90 ? 92 GLU R N 1 +ATOM 33059 C CA . GLU R 1 92 ? 22.983 12.902 17.200 1.00 90.66 ? 92 GLU R CA 1 +ATOM 33060 C C . GLU R 1 92 ? 23.104 11.530 16.538 1.00 80.71 ? 92 GLU R C 1 +ATOM 33061 O O . GLU R 1 92 ? 22.096 10.831 16.313 1.00 52.57 ? 92 GLU R O 1 +ATOM 33062 C CB . GLU R 1 92 ? 22.979 13.976 16.113 1.00 70.93 ? 92 GLU R CB 1 +ATOM 33063 C CG . GLU R 1 92 ? 22.118 15.184 16.420 1.00 61.51 ? 92 GLU R CG 1 +ATOM 33064 C CD . GLU R 1 92 ? 20.689 14.827 16.824 1.00 78.00 ? 92 GLU R CD 1 +ATOM 33065 O OE1 . GLU R 1 92 ? 19.939 14.134 16.022 1.00 96.30 ? 92 GLU R OE1 1 +ATOM 33066 O OE2 . GLU R 1 92 ? 20.309 15.239 17.964 1.00 68.44 ? 92 GLU R OE2 1 +ATOM 33067 N N . ARG R 1 93 ? 24.342 11.114 16.307 1.00 66.45 ? 93 ARG R N 1 +ATOM 33068 C CA . ARG R 1 93 ? 24.570 9.782 15.797 1.00 85.41 ? 93 ARG R CA 1 +ATOM 33069 C C . ARG R 1 93 ? 24.200 8.663 16.826 1.00 83.52 ? 93 ARG R C 1 +ATOM 33070 O O . ARG R 1 93 ? 23.710 7.587 16.449 1.00 57.66 ? 93 ARG R O 1 +ATOM 33071 C CB . ARG R 1 93 ? 26.008 9.677 15.276 1.00 85.38 ? 93 ARG R CB 1 +ATOM 33072 C CG . ARG R 1 93 ? 26.225 10.543 14.049 1.00 71.56 ? 93 ARG R CG 1 +ATOM 33073 C CD . ARG R 1 93 ? 27.691 10.770 13.710 1.00 81.83 ? 93 ARG R CD 1 +ATOM 33074 N NE . ARG R 1 93 ? 28.149 9.935 12.605 1.00 76.89 ? 93 ARG R NE 1 +ATOM 33075 C CZ . ARG R 1 93 ? 28.797 8.790 12.742 1.00 94.72 ? 93 ARG R CZ 1 +ATOM 33076 N NH1 . ARG R 1 93 ? 29.089 8.292 13.944 1.00 124.00 ? 93 ARG R NH1 1 +ATOM 33077 N NH2 . ARG R 1 93 ? 29.174 8.137 11.664 1.00 119.28 ? 93 ARG R NH2 1 +ATOM 33078 N N . LYS R 1 94 ? 24.403 8.919 18.115 1.00 76.53 ? 94 LYS R N 1 +ATOM 33079 C CA . LYS R 1 94 ? 23.960 7.969 19.140 1.00 81.88 ? 94 LYS R CA 1 +ATOM 33080 C C . LYS R 1 94 ? 22.440 7.838 19.099 1.00 70.57 ? 94 LYS R C 1 +ATOM 33081 O O . LYS R 1 94 ? 21.898 6.738 19.247 1.00 49.09 ? 94 LYS R O 1 +ATOM 33082 C CB . LYS R 1 94 ? 24.376 8.435 20.532 1.00 100.35 ? 94 LYS R CB 1 +ATOM 33083 C CG . LYS R 1 94 ? 25.755 7.985 21.000 1.00 115.05 ? 94 LYS R CG 1 +ATOM 33084 C CD . LYS R 1 94 ? 26.107 8.684 22.309 1.00 125.22 ? 94 LYS R CD 1 +ATOM 33085 C CE . LYS R 1 94 ? 27.195 7.971 23.095 1.00 127.37 ? 94 LYS R CE 1 +ATOM 33086 N NZ . LYS R 1 94 ? 27.725 8.867 24.160 1.00 137.82 ? 94 LYS R NZ 1 +ATOM 33087 N N . ILE R 1 95 ? 21.764 8.977 18.900 1.00 69.50 ? 95 ILE R N 1 +ATOM 33088 C CA . ILE R 1 95 ? 20.305 9.016 18.961 1.00 66.94 ? 95 ILE R CA 1 +ATOM 33089 C C . ILE R 1 95 ? 19.711 8.325 17.746 1.00 87.66 ? 95 ILE R C 1 +ATOM 33090 O O . ILE R 1 95 ? 18.710 7.561 17.881 1.00 80.43 ? 95 ILE R O 1 +ATOM 33091 C CB . ILE R 1 95 ? 19.709 10.427 19.030 1.00 49.44 ? 95 ILE R CB 1 +ATOM 33092 C CG1 . ILE R 1 95 ? 20.379 11.246 20.109 1.00 70.54 ? 95 ILE R CG1 1 +ATOM 33093 C CG2 . ILE R 1 95 ? 18.252 10.296 19.395 1.00 54.62 ? 95 ILE R CG2 1 +ATOM 33094 C CD1 . ILE R 1 95 ? 19.660 12.514 20.498 1.00 79.96 ? 95 ILE R CD1 1 +ATOM 33095 N N . ILE R 1 96 ? 20.351 8.570 16.595 1.00 76.82 ? 96 ILE R N 1 +ATOM 33096 C CA . ILE R 1 96 ? 20.058 7.823 15.390 1.00 74.65 ? 96 ILE R CA 1 +ATOM 33097 C C . ILE R 1 96 ? 20.180 6.322 15.635 1.00 87.65 ? 96 ILE R C 1 +ATOM 33098 O O . ILE R 1 96 ? 19.201 5.578 15.461 1.00 135.96 ? 96 ILE R O 1 +ATOM 33099 C CB . ILE R 1 96 ? 20.972 8.204 14.218 1.00 58.34 ? 96 ILE R CB 1 +ATOM 33100 C CG1 . ILE R 1 96 ? 20.709 9.639 13.829 1.00 69.60 ? 96 ILE R CG1 1 +ATOM 33101 C CG2 . ILE R 1 96 ? 20.682 7.310 13.013 1.00 50.87 ? 96 ILE R CG2 1 +ATOM 33102 C CD1 . ILE R 1 96 ? 21.509 10.074 12.623 1.00 100.30 ? 96 ILE R CD1 1 +ATOM 33103 N N . ARG R 1 97 ? 21.367 5.877 16.029 1.00 71.05 ? 97 ARG R N 1 +ATOM 33104 C CA . ARG R 1 97 ? 21.616 4.455 16.181 1.00 78.27 ? 97 ARG R CA 1 +ATOM 33105 C C . ARG R 1 97 ? 20.663 3.836 17.202 1.00 79.89 ? 97 ARG R C 1 +ATOM 33106 O O . ARG R 1 97 ? 20.316 2.633 17.101 1.00 103.28 ? 97 ARG R O 1 +ATOM 33107 C CB . ARG R 1 97 ? 23.065 4.186 16.588 1.00 90.41 ? 97 ARG R CB 1 +ATOM 33108 C CG . ARG R 1 97 ? 23.954 3.680 15.462 1.00 103.95 ? 97 ARG R CG 1 +ATOM 33109 C CD . ARG R 1 97 ? 25.358 3.376 15.973 1.00 111.25 ? 97 ARG R CD 1 +ATOM 33110 N NE . ARG R 1 97 ? 26.173 4.581 16.092 1.00 93.38 ? 97 ARG R NE 1 +ATOM 33111 C CZ . ARG R 1 97 ? 27.050 4.984 15.172 1.00 107.86 ? 97 ARG R CZ 1 +ATOM 33112 N NH1 . ARG R 1 97 ? 27.262 4.289 14.038 1.00 102.98 ? 97 ARG R NH1 1 +ATOM 33113 N NH2 . ARG R 1 97 ? 27.728 6.100 15.380 1.00 121.56 ? 97 ARG R NH2 1 +ATOM 33114 N N . ALA R 1 98 ? 20.277 4.617 18.210 1.00 53.49 ? 98 ALA R N 1 +ATOM 33115 C CA . ALA R 1 98 ? 19.362 4.112 19.207 1.00 59.41 ? 98 ALA R CA 1 +ATOM 33116 C C . ALA R 1 98 ? 17.944 3.990 18.648 1.00 76.40 ? 98 ALA R C 1 +ATOM 33117 O O . ALA R 1 98 ? 17.138 3.132 19.084 1.00 74.49 ? 98 ALA R O 1 +ATOM 33118 C CB . ALA R 1 98 ? 19.384 5.004 20.411 1.00 51.38 ? 98 ALA R CB 1 +ATOM 33119 N N . ALA R 1 99 ? 17.655 4.843 17.671 1.00 87.19 ? 99 ALA R N 1 +ATOM 33120 C CA . ALA R 1 99 ? 16.345 4.867 17.042 1.00 90.22 ? 99 ALA R CA 1 +ATOM 33121 C C . ALA R 1 99 ? 16.096 3.600 16.221 1.00 63.28 ? 99 ALA R C 1 +ATOM 33122 O O . ALA R 1 99 ? 15.049 2.972 16.320 1.00 38.74 ? 99 ALA R O 1 +ATOM 33123 C CB . ALA R 1 99 ? 16.194 6.130 16.177 1.00 94.56 ? 99 ALA R CB 1 +ATOM 33124 N N . GLN R 1 100 ? 17.054 3.282 15.364 1.00 69.30 ? 100 GLN R N 1 +ATOM 33125 C CA . GLN R 1 100 ? 16.797 2.380 14.238 1.00 99.67 ? 100 GLN R CA 1 +ATOM 33126 C C . GLN R 1 100 ? 17.468 1.029 14.402 1.00 87.68 ? 100 GLN R C 1 +ATOM 33127 O O . GLN R 1 100 ? 17.406 0.183 13.500 1.00 91.91 ? 100 GLN R O 1 +ATOM 33128 C CB . GLN R 1 100 ? 17.220 3.008 12.891 1.00 111.82 ? 100 GLN R CB 1 +ATOM 33129 C CG . GLN R 1 100 ? 18.550 3.746 12.909 1.00 108.05 ? 100 GLN R CG 1 +ATOM 33130 C CD . GLN R 1 100 ? 18.656 4.865 11.877 1.00 98.81 ? 100 GLN R CD 1 +ATOM 33131 O OE1 . GLN R 1 100 ? 17.855 5.823 11.853 1.00 57.77 ? 100 GLN R OE1 1 +ATOM 33132 N NE2 . GLN R 1 100 ? 19.658 4.744 11.019 1.00 97.38 ? 100 GLN R NE2 1 +ATOM 33133 N N . GLU R 1 101 ? 18.048 0.801 15.570 1.00 82.17 ? 101 GLU R N 1 +ATOM 33134 C CA . GLU R 1 101 ? 18.691 -0.487 15.847 1.00 104.96 ? 101 GLU R CA 1 +ATOM 33135 C C . GLU R 1 101 ? 17.729 -1.700 15.865 1.00 92.22 ? 101 GLU R C 1 +ATOM 33136 O O . GLU R 1 101 ? 18.154 -2.827 15.664 1.00 84.43 ? 101 GLU R O 1 +ATOM 33137 C CB . GLU R 1 101 ? 19.495 -0.408 17.153 1.00 112.40 ? 101 GLU R CB 1 +ATOM 33138 C CG . GLU R 1 101 ? 18.704 0.073 18.362 1.00 117.46 ? 101 GLU R CG 1 +ATOM 33139 C CD . GLU R 1 101 ? 19.526 0.060 19.643 1.00 120.86 ? 101 GLU R CD 1 +ATOM 33140 O OE1 . GLU R 1 101 ? 20.773 0.005 19.544 1.00 125.74 ? 101 GLU R OE1 1 +ATOM 33141 O OE2 . GLU R 1 101 ? 18.933 0.118 20.745 1.00 98.12 ? 101 GLU R OE2 1 +ATOM 33142 N N . ASN R 1 102 ? 16.450 -1.462 16.124 1.00 76.04 ? 102 ASN R N 1 +ATOM 33143 C CA . ASN R 1 102 ? 15.505 -2.546 16.261 1.00 59.04 ? 102 ASN R CA 1 +ATOM 33144 C C . ASN R 1 102 ? 14.827 -2.879 14.961 1.00 67.24 ? 102 ASN R C 1 +ATOM 33145 O O . ASN R 1 102 ? 13.949 -3.747 14.914 1.00 96.00 ? 102 ASN R O 1 +ATOM 33146 C CB . ASN R 1 102 ? 14.484 -2.214 17.349 1.00 53.04 ? 102 ASN R CB 1 +ATOM 33147 C CG . ASN R 1 102 ? 15.090 -2.306 18.712 1.00 73.92 ? 102 ASN R CG 1 +ATOM 33148 O OD1 . ASN R 1 102 ? 15.291 -3.401 19.267 1.00 91.53 ? 102 ASN R OD1 1 +ATOM 33149 N ND2 . ASN R 1 102 ? 15.455 -1.153 19.259 1.00 117.86 ? 102 ASN R ND2 1 +ATOM 33150 N N . GLY R 1 103 ? 15.113 -2.112 13.920 1.00 75.30 ? 103 GLY R N 1 +ATOM 33151 C CA . GLY R 1 103 ? 14.376 -2.277 12.644 1.00 110.40 ? 103 GLY R CA 1 +ATOM 33152 C C . GLY R 1 103 ? 12.847 -2.135 12.682 1.00 88.04 ? 103 GLY R C 1 +ATOM 33153 O O . GLY R 1 103 ? 12.122 -2.816 11.980 1.00 69.54 ? 103 GLY R O 1 +ATOM 33154 N N . THR R 1 104 ? 12.374 -1.235 13.520 1.00 109.78 ? 104 THR R N 1 +ATOM 33155 C CA . THR R 1 104 ? 10.999 -0.845 13.485 1.00 112.08 ? 104 THR R CA 1 +ATOM 33156 C C . THR R 1 104 ? 10.886 0.467 12.750 1.00 103.86 ? 104 THR R C 1 +ATOM 33157 O O . THR R 1 104 ? 9.833 0.749 12.196 1.00 137.90 ? 104 THR R O 1 +ATOM 33158 C CB . THR R 1 104 ? 10.379 -0.747 14.909 1.00 137.26 ? 104 THR R CB 1 +ATOM 33159 O OG1 . THR R 1 104 ? 11.003 0.289 15.686 1.00 155.81 ? 104 THR R OG1 1 +ATOM 33160 C CG2 . THR R 1 104 ? 10.522 -2.085 15.650 1.00 147.83 ? 104 THR R CG2 1 +ATOM 33161 N N . VAL R 1 105 ? 11.928 1.297 12.793 1.00 85.88 ? 105 VAL R N 1 +ATOM 33162 C CA . VAL R 1 105 ? 11.799 2.666 12.317 1.00 95.82 ? 105 VAL R CA 1 +ATOM 33163 C C . VAL R 1 105 ? 11.383 2.665 10.844 1.00 109.92 ? 105 VAL R C 1 +ATOM 33164 O O . VAL R 1 105 ? 11.848 1.845 10.046 1.00 97.70 ? 105 VAL R O 1 +ATOM 33165 C CB . VAL R 1 105 ? 13.071 3.528 12.559 1.00 110.87 ? 105 VAL R CB 1 +ATOM 33166 C CG1 . VAL R 1 105 ? 13.302 4.544 11.427 1.00 140.13 ? 105 VAL R CG1 1 +ATOM 33167 C CG2 . VAL R 1 105 ? 12.989 4.277 13.892 1.00 105.86 ? 105 VAL R CG2 1 +ATOM 33168 N N . ALA R 1 106 ? 10.493 3.608 10.512 1.00 119.28 ? 106 ALA R N 1 +ATOM 33169 C CA . ALA R 1 106 ? 9.852 3.700 9.204 1.00 102.50 ? 106 ALA R CA 1 +ATOM 33170 C C . ALA R 1 106 ? 10.887 3.911 8.103 1.00 112.63 ? 106 ALA R C 1 +ATOM 33171 O O . ALA R 1 106 ? 11.768 4.771 8.219 1.00 163.19 ? 106 ALA R O 1 +ATOM 33172 C CB . ALA R 1 106 ? 8.822 4.834 9.201 1.00 82.69 ? 106 ALA R CB 1 +ATOM 33173 N N . ILE R 1 107 ? 10.764 3.131 7.034 1.00 109.84 ? 107 ILE R N 1 +ATOM 33174 C CA . ILE R 1 107 ? 11.742 3.126 5.947 1.00 112.79 ? 107 ILE R CA 1 +ATOM 33175 C C . ILE R 1 107 ? 11.947 4.521 5.296 1.00 120.44 ? 107 ILE R C 1 +ATOM 33176 O O . ILE R 1 107 ? 13.040 4.852 4.831 1.00 89.39 ? 107 ILE R O 1 +ATOM 33177 C CB . ILE R 1 107 ? 11.345 2.080 4.881 1.00 106.79 ? 107 ILE R CB 1 +ATOM 33178 C CG1 . ILE R 1 107 ? 12.499 1.825 3.914 1.00 110.54 ? 107 ILE R CG1 1 +ATOM 33179 C CG2 . ILE R 1 107 ? 10.093 2.527 4.121 1.00 112.09 ? 107 ILE R CG2 1 +ATOM 33180 C CD1 . ILE R 1 107 ? 13.787 1.366 4.575 1.00 110.57 ? 107 ILE R CD1 1 +ATOM 33181 N N . ASN R 1 108 ? 10.895 5.338 5.289 1.00 134.57 ? 108 ASN R N 1 +ATOM 33182 C CA . ASN R 1 108 ? 10.974 6.728 4.814 1.00 130.17 ? 108 ASN R CA 1 +ATOM 33183 C C . ASN R 1 108 ? 11.784 7.599 5.769 1.00 114.71 ? 108 ASN R C 1 +ATOM 33184 O O . ASN R 1 108 ? 12.483 8.519 5.353 1.00 136.24 ? 108 ASN R O 1 +ATOM 33185 C CB . ASN R 1 108 ? 9.569 7.335 4.671 1.00 126.56 ? 108 ASN R CB 1 +ATOM 33186 C CG . ASN R 1 108 ? 8.516 6.298 4.325 1.00 153.42 ? 108 ASN R CG 1 +ATOM 33187 O OD1 . ASN R 1 108 ? 8.306 5.979 3.151 1.00 217.66 ? 108 ASN R OD1 1 +ATOM 33188 N ND2 . ASN R 1 108 ? 7.859 5.753 5.344 1.00 131.60 ? 108 ASN R ND2 1 +ATOM 33189 N N . ASN R 1 109 ? 11.654 7.310 7.053 1.00 99.35 ? 109 ASN R N 1 +ATOM 33190 C CA . ASN R 1 109 ? 12.251 8.115 8.102 1.00 110.55 ? 109 ASN R CA 1 +ATOM 33191 C C . ASN R 1 109 ? 13.685 7.715 8.418 1.00 106.37 ? 109 ASN R C 1 +ATOM 33192 O O . ASN R 1 109 ? 14.433 8.483 9.044 1.00 160.92 ? 109 ASN R O 1 +ATOM 33193 C CB . ASN R 1 109 ? 11.403 8.017 9.369 1.00 134.86 ? 109 ASN R CB 1 +ATOM 33194 C CG . ASN R 1 109 ? 10.810 9.351 9.765 1.00 158.35 ? 109 ASN R CG 1 +ATOM 33195 O OD1 . ASN R 1 109 ? 11.139 9.898 10.814 1.00 186.46 ? 109 ASN R OD1 1 +ATOM 33196 N ND2 . ASN R 1 109 ? 9.937 9.891 8.915 1.00 160.66 ? 109 ASN R ND2 1 +ATOM 33197 N N . ARG R 1 110 ? 14.072 6.525 7.957 1.00 97.66 ? 110 ARG R N 1 +ATOM 33198 C CA . ARG R 1 110 ? 15.374 5.908 8.289 1.00 87.46 ? 110 ARG R CA 1 +ATOM 33199 C C . ARG R 1 110 ? 16.556 6.801 7.886 1.00 90.95 ? 110 ARG R C 1 +ATOM 33200 O O . ARG R 1 110 ? 16.553 7.368 6.785 1.00 138.68 ? 110 ARG R O 1 +ATOM 33201 C CB . ARG R 1 110 ? 15.497 4.565 7.559 1.00 82.32 ? 110 ARG R CB 1 +ATOM 33202 C CG . ARG R 1 110 ? 16.470 3.586 8.179 1.00 91.22 ? 110 ARG R CG 1 +ATOM 33203 C CD . ARG R 1 110 ? 16.009 2.148 8.005 1.00 105.83 ? 110 ARG R CD 1 +ATOM 33204 N NE . ARG R 1 110 ? 16.481 1.557 6.750 1.00 110.97 ? 110 ARG R NE 1 +ATOM 33205 C CZ . ARG R 1 110 ? 17.269 0.484 6.662 1.00 139.65 ? 110 ARG R CZ 1 +ATOM 33206 N NH1 . ARG R 1 110 ? 17.691 -0.166 7.759 1.00 144.44 ? 110 ARG R NH1 1 +ATOM 33207 N NH2 . ARG R 1 110 ? 17.627 0.030 5.463 1.00 140.56 ? 110 ARG R NH2 1 +ATOM 33208 N N . ILE R 1 111 ? 17.535 6.968 8.775 1.00 67.71 ? 111 ILE R N 1 +ATOM 33209 C CA . ILE R 1 111 ? 18.737 7.711 8.430 1.00 71.64 ? 111 ILE R CA 1 +ATOM 33210 C C . ILE R 1 111 ? 19.897 6.765 8.302 1.00 92.25 ? 111 ILE R C 1 +ATOM 33211 O O . ILE R 1 111 ? 20.290 6.156 9.288 1.00 100.48 ? 111 ILE R O 1 +ATOM 33212 C CB . ILE R 1 111 ? 19.093 8.757 9.478 1.00 83.42 ? 111 ILE R CB 1 +ATOM 33213 C CG1 . ILE R 1 111 ? 17.996 9.830 9.528 1.00 91.76 ? 111 ILE R CG1 1 +ATOM 33214 C CG2 . ILE R 1 111 ? 20.435 9.409 9.139 1.00 109.05 ? 111 ILE R CG2 1 +ATOM 33215 C CD1 . ILE R 1 111 ? 18.080 10.791 10.715 1.00 68.85 ? 111 ILE R CD1 1 +ATOM 33216 N N . PRO R 1 112 ? 20.463 6.634 7.079 1.00 106.27 ? 112 PRO R N 1 +ATOM 33217 C CA . PRO R 1 112 ? 21.583 5.713 6.873 1.00 89.96 ? 112 PRO R CA 1 +ATOM 33218 C C . PRO R 1 112 ? 22.913 6.299 7.375 1.00 96.63 ? 112 PRO R C 1 +ATOM 33219 O O . PRO R 1 112 ? 23.254 7.453 7.067 1.00 91.11 ? 112 PRO R O 1 +ATOM 33220 C CB . PRO R 1 112 ? 21.609 5.550 5.366 1.00 84.41 ? 112 PRO R CB 1 +ATOM 33221 C CG . PRO R 1 112 ? 21.149 6.876 4.847 1.00 95.03 ? 112 PRO R CG 1 +ATOM 33222 C CD . PRO R 1 112 ? 20.231 7.472 5.886 1.00 100.89 ? 112 PRO R CD 1 +ATOM 33223 N N . LEU R 1 113 ? 23.608 5.531 8.208 1.00 88.41 ? 113 LEU R N 1 +ATOM 33224 C CA . LEU R 1 113 ? 24.794 6.016 8.902 1.00 79.93 ? 113 LEU R CA 1 +ATOM 33225 C C . LEU R 1 113 ? 26.035 5.363 8.353 1.00 76.58 ? 113 LEU R C 1 +ATOM 33226 O O . LEU R 1 113 ? 26.055 4.160 8.047 1.00 85.14 ? 113 LEU R O 1 +ATOM 33227 C CB . LEU R 1 113 ? 24.713 5.740 10.414 1.00 70.65 ? 113 LEU R CB 1 +ATOM 33228 C CG . LEU R 1 113 ? 24.001 6.810 11.235 1.00 67.66 ? 113 LEU R CG 1 +ATOM 33229 C CD1 . LEU R 1 113 ? 24.131 6.399 12.681 1.00 87.98 ? 113 LEU R CD1 1 +ATOM 33230 C CD2 . LEU R 1 113 ? 24.586 8.202 11.038 1.00 66.62 ? 113 LEU R CD2 1 +ATOM 33231 N N . GLN R 1 114 ? 27.116 6.113 8.390 1.00 72.06 ? 114 GLN R N 1 +ATOM 33232 C CA . GLN R 1 114 ? 28.408 5.511 8.149 1.00 86.34 ? 114 GLN R CA 1 +ATOM 33233 C C . GLN R 1 114 ? 29.344 6.269 9.042 1.00 84.08 ? 114 GLN R C 1 +ATOM 33234 O O . GLN R 1 114 ? 29.180 7.478 9.209 1.00 139.44 ? 114 GLN R O 1 +ATOM 33235 C CB . GLN R 1 114 ? 28.808 5.649 6.678 1.00 103.46 ? 114 GLN R CB 1 +ATOM 33236 C CG . GLN R 1 114 ? 29.800 4.610 6.165 1.00 91.40 ? 114 GLN R CG 1 +ATOM 33237 C CD . GLN R 1 114 ? 30.839 5.264 5.292 1.00 96.26 ? 114 GLN R CD 1 +ATOM 33238 O OE1 . GLN R 1 114 ? 32.019 5.037 5.495 1.00 58.47 ? 114 GLN R OE1 1 +ATOM 33239 N NE2 . GLN R 1 114 ? 30.414 6.223 4.446 1.00 125.49 ? 114 GLN R NE2 1 +ATOM 33240 N N . SER R 1 115 ? 30.373 5.596 9.530 1.00 82.05 ? 115 SER R N 1 +ATOM 33241 C CA . SER R 1 115 ? 31.399 6.248 10.331 1.00 77.52 ? 115 SER R CA 1 +ATOM 33242 C C . SER R 1 115 ? 31.952 7.490 9.521 1.00 55.95 ? 115 SER R C 1 +ATOM 33243 O O . SER R 1 115 ? 32.011 7.526 8.397 1.00 29.53 ? 115 SER R O 1 +ATOM 33244 C CB . SER R 1 115 ? 32.476 5.215 10.763 1.00 66.00 ? 115 SER R CB 1 +ATOM 33245 O OG . SER R 1 115 ? 33.071 4.628 9.626 1.00 110.41 ? 115 SER R OG 1 +ATOM 33246 N N . LEU R 1 116 ? 32.523 8.408 10.204 1.00 59.82 ? 116 LEU R N 1 +ATOM 33247 C CA . LEU R 1 116 ? 32.646 9.804 9.889 1.00 65.06 ? 116 LEU R CA 1 +ATOM 33248 C C . LEU R 1 116 ? 33.688 9.969 8.828 1.00 60.70 ? 116 LEU R C 1 +ATOM 33249 O O . LEU R 1 116 ? 34.835 9.543 9.014 1.00 80.62 ? 116 LEU R O 1 +ATOM 33250 C CB . LEU R 1 116 ? 33.049 10.534 11.208 1.00 92.26 ? 116 LEU R CB 1 +ATOM 33251 C CG . LEU R 1 116 ? 31.994 10.474 12.340 1.00 93.78 ? 116 LEU R CG 1 +ATOM 33252 C CD1 . LEU R 1 116 ? 32.229 9.278 13.286 1.00 86.09 ? 116 LEU R CD1 1 +ATOM 33253 C CD2 . LEU R 1 116 ? 32.023 11.787 13.114 1.00 84.90 ? 116 LEU R CD2 1 +ATOM 33254 N N . THR R 1 117 ? 33.366 10.772 7.825 1.00 70.16 ? 117 THR R N 1 +ATOM 33255 C CA . THR R 1 117 ? 34.348 11.191 6.810 1.00 102.55 ? 117 THR R CA 1 +ATOM 33256 C C . THR R 1 117 ? 35.570 11.862 7.434 1.00 99.21 ? 117 THR R C 1 +ATOM 33257 O O . THR R 1 117 ? 35.442 12.681 8.329 1.00 98.82 ? 117 THR R O 1 +ATOM 33258 C CB . THR R 1 117 ? 33.772 12.218 5.804 1.00 133.28 ? 117 THR R CB 1 +ATOM 33259 O OG1 . THR R 1 117 ? 32.539 11.724 5.270 1.00 147.23 ? 117 THR R OG1 1 +ATOM 33260 C CG2 . THR R 1 117 ? 34.737 12.445 4.666 1.00 153.73 ? 117 THR R CG2 1 +ATOM 33261 N N . ALA R 1 118 ? 36.753 11.429 7.013 1.00 114.49 ? 118 ALA R N 1 +ATOM 33262 C CA . ALA R 1 118 ? 37.989 11.751 7.734 1.00 100.83 ? 118 ALA R CA 1 +ATOM 33263 C C . ALA R 1 118 ? 38.844 12.594 6.843 1.00 74.43 ? 118 ALA R C 1 +ATOM 33264 O O . ALA R 1 118 ? 39.077 12.244 5.688 1.00 67.95 ? 118 ALA R O 1 +ATOM 33265 C CB . ALA R 1 118 ? 38.735 10.471 8.187 1.00 91.88 ? 118 ALA R CB 1 +ATOM 33266 N N . ALA R 1 119 ? 39.481 13.556 7.467 1.00 78.08 ? 119 ALA R N 1 +ATOM 33267 C CA . ALA R 1 119 ? 40.379 14.464 6.788 1.00 104.92 ? 119 ALA R CA 1 +ATOM 33268 C C . ALA R 1 119 ? 41.812 13.929 6.598 1.00 96.78 ? 119 ALA R C 1 +ATOM 33269 O O . ALA R 1 119 ? 42.294 13.121 7.389 1.00 93.55 ? 119 ALA R O 1 +ATOM 33270 C CB . ALA R 1 119 ? 40.412 15.753 7.574 1.00 123.23 ? 119 ALA R CB 1 +ATOM 33271 N N . ASN R 1 120 ? 42.512 14.434 5.588 1.00 92.54 ? 120 ASN R N 1 +ATOM 33272 C CA . ASN R 1 120 ? 43.914 14.105 5.428 1.00 89.71 ? 120 ASN R CA 1 +ATOM 33273 C C . ASN R 1 120 ? 44.824 15.185 5.990 1.00 82.48 ? 120 ASN R C 1 +ATOM 33274 O O . ASN R 1 120 ? 45.862 14.890 6.619 1.00 120.04 ? 120 ASN R O 1 +ATOM 33275 C CB . ASN R 1 120 ? 44.283 13.856 3.966 1.00 102.38 ? 120 ASN R CB 1 +ATOM 33276 C CG . ASN R 1 120 ? 45.749 13.412 3.806 1.00 122.01 ? 120 ASN R CG 1 +ATOM 33277 O OD1 . ASN R 1 120 ? 46.420 13.865 2.879 1.00 173.93 ? 120 ASN R OD1 1 +ATOM 33278 N ND2 . ASN R 1 120 ? 46.272 12.587 4.747 1.00 92.95 ? 120 ASN R ND2 1 +ATOM 33279 N N . ILE R 1 121 ? 44.537 16.431 5.645 1.00 60.10 ? 121 ILE R N 1 +ATOM 33280 C CA . ILE R 1 121 ? 45.299 17.509 6.204 1.00 66.90 ? 121 ILE R CA 1 +ATOM 33281 C C . ILE R 1 121 ? 44.375 18.241 7.151 1.00 87.82 ? 121 ILE R C 1 +ATOM 33282 O O . ILE R 1 121 ? 43.192 18.383 6.879 1.00 63.92 ? 121 ILE R O 1 +ATOM 33283 C CB . ILE R 1 121 ? 45.883 18.468 5.131 1.00 62.30 ? 121 ILE R CB 1 +ATOM 33284 C CG1 . ILE R 1 121 ? 44.804 19.354 4.488 1.00 48.05 ? 121 ILE R CG1 1 +ATOM 33285 C CG2 . ILE R 1 121 ? 46.676 17.692 4.077 1.00 57.57 ? 121 ILE R CG2 1 +ATOM 33286 C CD1 . ILE R 1 121 ? 44.898 20.821 4.877 1.00 50.30 ? 121 ILE R CD1 1 +ATOM 33287 N N . MET R 1 122 ? 44.912 18.685 8.289 1.00 92.18 ? 122 MET R N 1 +ATOM 33288 C CA . MET R 1 122 ? 44.161 19.611 9.131 1.00 71.36 ? 122 MET R CA 1 +ATOM 33289 C C . MET R 1 122 ? 44.955 20.875 9.371 1.00 63.93 ? 122 MET R C 1 +ATOM 33290 O O . MET R 1 122 ? 46.181 20.865 9.292 1.00 51.75 ? 122 MET R O 1 +ATOM 33291 C CB . MET R 1 122 ? 43.792 18.958 10.433 1.00 70.06 ? 122 MET R CB 1 +ATOM 33292 C CG . MET R 1 122 ? 44.959 18.444 11.251 1.00 75.45 ? 122 MET R CG 1 +ATOM 33293 S SD . MET R 1 122 ? 44.539 18.493 12.998 1.00 112.27 ? 122 MET R SD 1 +ATOM 33294 C CE . MET R 1 122 ? 46.048 19.093 13.743 1.00 68.16 ? 122 MET R CE 1 +ATOM 33295 N N . VAL R 1 123 ? 44.251 21.998 9.366 1.00 70.91 ? 123 VAL R N 1 +ATOM 33296 C CA . VAL R 1 123 ? 44.909 23.305 9.399 1.00 78.51 ? 123 VAL R CA 1 +ATOM 33297 C C . VAL R 1 123 ? 44.468 24.016 10.644 1.00 88.94 ? 123 VAL R C 1 +ATOM 33298 O O . VAL R 1 123 ? 43.282 24.159 10.898 1.00 69.36 ? 123 VAL R O 1 +ATOM 33299 C CB . VAL R 1 123 ? 44.598 24.212 8.190 1.00 81.15 ? 123 VAL R CB 1 +ATOM 33300 C CG1 . VAL R 1 123 ? 43.146 24.108 7.773 1.00 90.83 ? 123 VAL R CG1 1 +ATOM 33301 C CG2 . VAL R 1 123 ? 44.945 25.664 8.509 1.00 110.93 ? 123 VAL R CG2 1 +ATOM 33302 N N . GLU R 1 124 ? 45.439 24.412 11.454 1.00 110.90 ? 124 GLU R N 1 +ATOM 33303 C CA . GLU R 1 124 ? 45.152 25.203 12.648 1.00 118.08 ? 124 GLU R CA 1 +ATOM 33304 C C . GLU R 1 124 ? 46.027 26.419 12.680 1.00 113.95 ? 124 GLU R C 1 +ATOM 33305 O O . GLU R 1 124 ? 46.926 26.579 11.859 1.00 118.23 ? 124 GLU R O 1 +ATOM 33306 C CB . GLU R 1 124 ? 45.366 24.405 13.927 1.00 116.57 ? 124 GLU R CB 1 +ATOM 33307 C CG . GLU R 1 124 ? 46.419 23.313 13.839 1.00 122.97 ? 124 GLU R CG 1 +ATOM 33308 C CD . GLU R 1 124 ? 46.271 22.283 14.944 1.00 125.76 ? 124 GLU R CD 1 +ATOM 33309 O OE1 . GLU R 1 124 ? 45.131 21.998 15.358 1.00 76.18 ? 124 GLU R OE1 1 +ATOM 33310 O OE2 . GLU R 1 124 ? 47.316 21.859 15.480 1.00 198.03 ? 124 GLU R OE2 1 +ATOM 33311 N N . GLY R 1 125 ? 45.723 27.313 13.602 1.00 106.63 ? 125 GLY R N 1 +ATOM 33312 C CA . GLY R 1 125 ? 46.386 28.599 13.631 1.00 111.04 ? 125 GLY R CA 1 +ATOM 33313 C C . GLY R 1 125 ? 46.035 29.386 14.862 1.00 107.60 ? 125 GLY R C 1 +ATOM 33314 O O . GLY R 1 125 ? 45.445 28.860 15.808 1.00 114.08 ? 125 GLY R O 1 +ATOM 33315 N N . SER R 1 126 ? 46.323 30.686 14.827 1.00 102.27 ? 126 SER R N 1 +ATOM 33316 C CA . SER R 1 126 ? 46.066 31.543 15.983 1.00 93.15 ? 126 SER R CA 1 +ATOM 33317 C C . SER R 1 126 ? 46.003 32.993 15.597 1.00 65.93 ? 126 SER R C 1 +ATOM 33318 O O . SER R 1 126 ? 46.588 33.388 14.606 1.00 58.13 ? 126 SER R O 1 +ATOM 33319 C CB . SER R 1 126 ? 47.201 31.441 16.967 1.00 118.43 ? 126 SER R CB 1 +ATOM 33320 O OG . SER R 1 126 ? 48.043 30.364 16.747 1.00 142.97 ? 126 SER R OG 1 +ATOM 33321 N N . ILE R 1 127 ? 45.200 33.767 16.308 1.00 52.53 ? 127 ILE R N 1 +ATOM 33322 C CA . ILE R 1 127 ? 45.266 35.178 16.140 1.00 63.00 ? 127 ILE R CA 1 +ATOM 33323 C C . ILE R 1 127 ? 46.471 35.560 16.961 1.00 72.71 ? 127 ILE R C 1 +ATOM 33324 O O . ILE R 1 127 ? 46.410 35.707 18.167 1.00 64.66 ? 127 ILE R O 1 +ATOM 33325 C CB . ILE R 1 127 ? 43.997 35.925 16.603 1.00 89.21 ? 127 ILE R CB 1 +ATOM 33326 C CG1 . ILE R 1 127 ? 42.811 35.611 15.679 1.00 96.06 ? 127 ILE R CG1 1 +ATOM 33327 C CG2 . ILE R 1 127 ? 44.224 37.446 16.625 1.00 108.73 ? 127 ILE R CG2 1 +ATOM 33328 C CD1 . ILE R 1 127 ? 41.460 35.643 16.382 1.00 103.94 ? 127 ILE R CD1 1 +ATOM 33329 N N . ILE R 1 128 ? 47.551 35.838 16.257 1.00 101.73 ? 128 ILE R N 1 +ATOM 33330 C CA . ILE R 1 128 ? 48.792 36.320 16.851 1.00 100.70 ? 128 ILE R CA 1 +ATOM 33331 C C . ILE R 1 128 ? 48.720 37.867 16.823 1.00 75.99 ? 128 ILE R C 1 +ATOM 33332 O O . ILE R 1 128 ? 48.899 38.504 15.783 1.00 127.52 ? 128 ILE R O 1 +ATOM 33333 C CB . ILE R 1 128 ? 50.005 35.727 16.074 1.00 113.54 ? 128 ILE R CB 1 +ATOM 33334 C CG1 . ILE R 1 128 ? 49.914 36.054 14.571 1.00 145.45 ? 128 ILE R CG1 1 +ATOM 33335 C CG2 . ILE R 1 128 ? 49.982 34.202 16.151 1.00 94.01 ? 128 ILE R CG2 1 +ATOM 33336 C CD1 . ILE R 1 128 ? 51.256 36.047 13.869 1.00 137.60 ? 128 ILE R CD1 1 +ATOM 33337 N N . GLY R 1 129 ? 48.310 38.452 17.926 1.00 47.64 ? 129 GLY R N 1 +ATOM 33338 C CA . GLY R 1 129 ? 48.558 39.840 18.147 1.00 47.52 ? 129 GLY R CA 1 +ATOM 33339 C C . GLY R 1 129 ? 47.452 40.752 17.674 1.00 65.40 ? 129 GLY R C 1 +ATOM 33340 O O . GLY R 1 129 ? 46.939 40.663 16.549 1.00 62.69 ? 129 GLY R O 1 +ATOM 33341 N N . TYR R 1 130 ? 47.171 41.739 18.519 1.00 115.07 ? 130 TYR R N 1 +ATOM 33342 C CA . TYR R 1 130 ? 46.428 42.949 18.135 1.00 113.52 ? 130 TYR R CA 1 +ATOM 33343 C C . TYR R 1 130 ? 47.075 44.093 18.879 1.00 129.59 ? 130 TYR R C 1 +ATOM 33344 O O . TYR R 1 130 ? 47.000 44.159 20.102 1.00 171.89 ? 130 TYR R O 1 +ATOM 33345 C CB . TYR R 1 130 ? 44.949 42.820 18.529 1.00 103.12 ? 130 TYR R CB 1 +ATOM 33346 C CG . TYR R 1 130 ? 44.093 44.041 18.317 1.00 105.46 ? 130 TYR R CG 1 +ATOM 33347 C CD1 . TYR R 1 130 ? 44.269 45.180 19.089 1.00 113.98 ? 130 TYR R CD1 1 +ATOM 33348 C CD2 . TYR R 1 130 ? 43.060 44.030 17.376 1.00 122.30 ? 130 TYR R CD2 1 +ATOM 33349 C CE1 . TYR R 1 130 ? 43.458 46.287 18.909 1.00 148.74 ? 130 TYR R CE1 1 +ATOM 33350 C CE2 . TYR R 1 130 ? 42.261 45.135 17.171 1.00 124.18 ? 130 TYR R CE2 1 +ATOM 33351 C CZ . TYR R 1 130 ? 42.464 46.261 17.932 1.00 155.97 ? 130 TYR R CZ 1 +ATOM 33352 O OH . TYR R 1 130 ? 41.654 47.357 17.724 1.00 204.64 ? 130 TYR R OH 1 +ATOM 33353 N N . GLU R 1 131 ? 47.837 44.911 18.171 1.00 118.89 ? 131 GLU R N 1 +ATOM 33354 C CA . GLU R 1 131 ? 48.366 46.133 18.770 1.00 138.25 ? 131 GLU R CA 1 +ATOM 33355 C C . GLU R 1 131 ? 47.429 47.288 18.423 1.00 119.96 ? 131 GLU R C 1 +ATOM 33356 O O . GLU R 1 131 ? 46.812 47.280 17.361 1.00 113.30 ? 131 GLU R O 1 +ATOM 33357 C CB . GLU R 1 131 ? 49.787 46.380 18.267 1.00 140.40 ? 131 GLU R CB 1 +ATOM 33358 C CG . GLU R 1 131 ? 50.552 47.494 18.973 1.00 121.21 ? 131 GLU R CG 1 +ATOM 33359 C CD . GLU R 1 131 ? 51.321 47.035 20.206 1.00 118.32 ? 131 GLU R CD 1 +ATOM 33360 O OE1 . GLU R 1 131 ? 51.740 45.848 20.262 1.00 87.02 ? 131 GLU R OE1 1 +ATOM 33361 O OE2 . GLU R 1 131 ? 51.491 47.873 21.124 1.00 138.42 ? 131 GLU R OE2 1 +ATOM 33362 N N . SER R 1 132 ? 47.310 48.258 19.323 1.00 97.26 ? 132 SER R N 1 +ATOM 33363 C CA . SER R 1 132 ? 46.299 49.299 19.171 1.00 99.90 ? 132 SER R CA 1 +ATOM 33364 C C . SER R 1 132 ? 46.922 50.695 19.086 1.00 125.65 ? 132 SER R C 1 +ATOM 33365 O O . SER R 1 132 ? 47.882 51.004 19.796 1.00 163.09 ? 132 SER R O 1 +ATOM 33366 C CB . SER R 1 132 ? 45.292 49.244 20.324 1.00 100.62 ? 132 SER R CB 1 +ATOM 33367 O OG . SER R 1 132 ? 45.390 50.395 21.157 1.00 93.41 ? 132 SER R OG 1 +ATOM 33368 N N . ASN R 1 133 ? 46.332 51.553 18.254 1.00 131.76 ? 133 ASN R N 1 +ATOM 33369 C CA . ASN R 1 133 ? 46.944 52.845 17.890 1.00 119.21 ? 133 ASN R CA 1 +ATOM 33370 C C . ASN R 1 133 ? 48.416 52.691 17.540 1.00 120.44 ? 133 ASN R C 1 +ATOM 33371 O O . ASN R 1 133 ? 49.285 53.326 18.141 1.00 100.68 ? 133 ASN R O 1 +ATOM 33372 C CB . ASN R 1 133 ? 46.784 53.869 19.004 1.00 96.71 ? 133 ASN R CB 1 +ATOM 33373 C CG . ASN R 1 133 ? 45.337 54.130 19.331 1.00 114.90 ? 133 ASN R CG 1 +ATOM 33374 O OD1 . ASN R 1 133 ? 44.443 54.027 18.469 1.00 137.57 ? 133 ASN R OD1 1 +ATOM 33375 N ND2 . ASN R 1 133 ? 45.084 54.458 20.581 1.00 136.25 ? 133 ASN R ND2 1 +ATOM 33376 N N . VAL R 1 134 ? 48.677 51.832 16.559 1.00 121.67 ? 134 VAL R N 1 +ATOM 33377 C CA . VAL R 1 134 ? 50.026 51.583 16.086 1.00 125.43 ? 134 VAL R CA 1 +ATOM 33378 C C . VAL R 1 134 ? 50.510 52.858 15.399 1.00 131.08 ? 134 VAL R C 1 +ATOM 33379 O O . VAL R 1 134 ? 51.682 53.227 15.502 1.00 103.95 ? 134 VAL R O 1 +ATOM 33380 C CB . VAL R 1 134 ? 50.060 50.377 15.116 1.00 127.26 ? 134 VAL R CB 1 +ATOM 33381 C CG1 . VAL R 1 134 ? 51.487 50.065 14.684 1.00 138.01 ? 134 VAL R CG1 1 +ATOM 33382 C CG2 . VAL R 1 134 ? 49.438 49.147 15.770 1.00 134.18 ? 134 VAL R CG2 1 +ATOM 33383 N N . LYS R 1 135 ? 49.582 53.548 14.739 1.00 140.80 ? 135 LYS R N 1 +ATOM 33384 C CA . LYS R 1 135 ? 49.803 54.934 14.340 1.00 136.69 ? 135 LYS R CA 1 +ATOM 33385 C C . LYS R 1 135 ? 48.580 55.796 14.615 1.00 152.51 ? 135 LYS R C 1 +ATOM 33386 O O . LYS R 1 135 ? 47.447 55.299 14.736 1.00 140.20 ? 135 LYS R O 1 +ATOM 33387 C CB . LYS R 1 135 ? 50.138 55.011 12.858 1.00 165.34 ? 135 LYS R CB 1 +ATOM 33388 C CG . LYS R 1 135 ? 51.422 54.290 12.490 1.00 185.82 ? 135 LYS R CG 1 +ATOM 33389 C CD . LYS R 1 135 ? 51.628 54.317 10.988 1.00 234.32 ? 135 LYS R CD 1 +ATOM 33390 C CE . LYS R 1 135 ? 52.898 53.596 10.589 1.00 237.71 ? 135 LYS R CE 1 +ATOM 33391 N NZ . LYS R 1 135 ? 53.344 54.042 9.244 1.00 272.88 ? 135 LYS R NZ 1 +ATOM 33392 N N . SER R 1 136 ? 48.814 57.103 14.692 1.00 177.29 ? 136 SER R N 1 +ATOM 33393 C CA . SER R 1 136 ? 47.736 58.061 14.929 1.00 192.37 ? 136 SER R CA 1 +ATOM 33394 C C . SER R 1 136 ? 48.155 59.483 14.569 1.00 192.27 ? 136 SER R C 1 +ATOM 33395 O O . SER R 1 136 ? 49.342 59.799 14.552 1.00 175.32 ? 136 SER R O 1 +ATOM 33396 C CB . SER R 1 136 ? 47.268 57.997 16.387 1.00 177.73 ? 136 SER R CB 1 +ATOM 33397 O OG . SER R 1 136 ? 47.324 59.270 17.011 1.00 141.66 ? 136 SER R OG 1 +ATOM 33398 N N . GLY R 1 137 ? 47.170 60.330 14.278 1.00 179.25 ? 137 GLY R N 1 +ATOM 33399 C CA . GLY R 1 137 ? 47.441 61.728 13.963 1.00 182.76 ? 137 GLY R CA 1 +ATOM 33400 C C . GLY R 1 137 ? 46.204 62.604 13.939 1.00 191.34 ? 137 GLY R C 1 +ATOM 33401 O O . GLY R 1 137 ? 45.083 62.130 14.132 1.00 195.74 ? 137 GLY R O 1 +ATOM 33402 N N . GLY R 1 138 ? 46.413 63.902 13.747 1.00 192.91 ? 138 GLY R N 1 +ATOM 33403 C CA . GLY R 1 138 ? 45.309 64.851 13.704 1.00 196.56 ? 138 GLY R CA 1 +ATOM 33404 C C . GLY R 1 138 ? 45.711 66.193 13.131 1.00 190.82 ? 138 GLY R C 1 +ATOM 33405 O O . GLY R 1 138 ? 46.839 66.651 13.329 1.00 134.39 ? 138 GLY R O 1 +ATOM 33406 N N . VAL R 1 139 ? 44.776 66.820 12.420 1.00 181.20 ? 139 VAL R N 1 +ATOM 33407 C CA . VAL R 1 139 ? 44.983 68.155 11.877 1.00 145.53 ? 139 VAL R CA 1 +ATOM 33408 C C . VAL R 1 139 ? 43.707 68.979 12.061 1.00 118.17 ? 139 VAL R C 1 +ATOM 33409 O O . VAL R 1 139 ? 42.634 68.594 11.592 1.00 80.20 ? 139 VAL R O 1 +ATOM 33410 C CB . VAL R 1 139 ? 45.361 68.110 10.377 1.00 122.23 ? 139 VAL R CB 1 +ATOM 33411 C CG1 . VAL R 1 139 ? 45.445 69.520 9.824 1.00 135.53 ? 139 VAL R CG1 1 +ATOM 33412 C CG2 . VAL R 1 139 ? 46.679 67.375 10.161 1.00 97.52 ? 139 VAL R CG2 1 +ATOM 33413 N N . GLY R 1 140 ? 43.848 70.141 12.693 1.00 119.38 ? 140 GLY R N 1 +ATOM 33414 C CA . GLY R 1 140 ? 42.723 71.047 12.890 1.00 130.73 ? 140 GLY R CA 1 +ATOM 33415 C C . GLY R 1 140 ? 43.087 72.521 12.912 1.00 165.06 ? 140 GLY R C 1 +ATOM 33416 O O . GLY R 1 140 ? 44.169 72.906 13.368 1.00 184.22 ? 140 GLY R O 1 +ATOM 33417 N N . ALA R 1 141 ? 42.169 73.358 12.431 1.00 174.48 ? 141 ALA R N 1 +ATOM 33418 C CA . ALA R 1 141 ? 42.366 74.808 12.466 1.00 152.89 ? 141 ALA R CA 1 +ATOM 33419 C C . ALA R 1 141 ? 41.058 75.556 12.730 1.00 137.69 ? 141 ALA R C 1 +ATOM 33420 O O . ALA R 1 141 ? 39.989 75.175 12.245 1.00 123.17 ? 141 ALA R O 1 +ATOM 33421 C CB . ALA R 1 141 ? 43.008 75.289 11.176 1.00 135.66 ? 141 ALA R CB 1 +ATOM 33422 N N . ARG R 1 142 ? 41.146 76.594 13.551 1.00 139.38 ? 142 ARG R N 1 +ATOM 33423 C CA . ARG R 1 142 ? 40.024 77.487 13.753 1.00 142.53 ? 142 ARG R CA 1 +ATOM 33424 C C . ARG R 1 142 ? 40.486 78.915 13.529 1.00 173.95 ? 142 ARG R C 1 +ATOM 33425 O O . ARG R 1 142 ? 41.638 79.255 13.813 1.00 192.95 ? 142 ARG R O 1 +ATOM 33426 C CB . ARG R 1 142 ? 39.425 77.331 15.148 1.00 138.12 ? 142 ARG R CB 1 +ATOM 33427 C CG . ARG R 1 142 ? 38.186 78.194 15.360 1.00 152.56 ? 142 ARG R CG 1 +ATOM 33428 C CD . ARG R 1 142 ? 37.077 77.466 16.106 1.00 179.10 ? 142 ARG R CD 1 +ATOM 33429 N NE . ARG R 1 142 ? 37.193 77.569 17.555 1.00 175.64 ? 142 ARG R NE 1 +ATOM 33430 C CZ . ARG R 1 142 ? 36.662 76.713 18.424 1.00 181.37 ? 142 ARG R CZ 1 +ATOM 33431 N NH1 . ARG R 1 142 ? 36.030 75.623 18.002 1.00 180.56 ? 142 ARG R NH1 1 +ATOM 33432 N NH2 . ARG R 1 142 ? 36.806 76.924 19.729 1.00 183.63 ? 142 ARG R NH2 1 +ATOM 33433 N N . TYR R 1 143 ? 39.602 79.722 12.946 1.00 188.51 ? 143 TYR R N 1 +ATOM 33434 C CA . TYR R 1 143 ? 39.954 81.064 12.488 1.00 177.42 ? 143 TYR R CA 1 +ATOM 33435 C C . TYR R 1 143 ? 38.911 82.080 12.979 1.00 126.79 ? 143 TYR R C 1 +ATOM 33436 O O . TYR R 1 143 ? 38.022 82.467 12.226 1.00 98.70 ? 143 TYR R O 1 +ATOM 33437 C CB . TYR R 1 143 ? 40.064 81.070 10.954 1.00 169.04 ? 143 TYR R CB 1 +ATOM 33438 C CG . TYR R 1 143 ? 40.579 82.350 10.373 1.00 182.91 ? 143 TYR R CG 1 +ATOM 33439 C CD1 . TYR R 1 143 ? 41.923 82.690 10.478 1.00 193.07 ? 143 TYR R CD1 1 +ATOM 33440 C CD2 . TYR R 1 143 ? 39.737 83.200 9.667 1.00 191.15 ? 143 TYR R CD2 1 +ATOM 33441 C CE1 . TYR R 1 143 ? 42.408 83.858 9.914 1.00 202.41 ? 143 TYR R CE1 1 +ATOM 33442 C CE2 . TYR R 1 143 ? 40.214 84.368 9.089 1.00 190.27 ? 143 TYR R CE2 1 +ATOM 33443 C CZ . TYR R 1 143 ? 41.549 84.694 9.220 1.00 196.15 ? 143 TYR R CZ 1 +ATOM 33444 O OH . TYR R 1 143 ? 42.027 85.851 8.656 1.00 191.69 ? 143 TYR R OH 1 +ATOM 33445 N N . GLY R 1 145 ? 33.893 82.926 13.834 1.00 135.79 ? 145 GLY R N 1 +ATOM 33446 C CA . GLY R 1 145 ? 35.020 82.030 14.047 1.00 163.20 ? 145 GLY R CA 1 +ATOM 33447 C C . GLY R 1 145 ? 34.734 80.589 13.633 1.00 189.26 ? 145 GLY R C 1 +ATOM 33448 O O . GLY R 1 145 ? 33.860 79.890 14.184 1.00 157.19 ? 145 GLY R O 1 +ATOM 33449 N N . ILE R 1 146 ? 35.459 80.165 12.610 1.00 224.95 ? 146 ILE R N 1 +ATOM 33450 C CA . ILE R 1 146 ? 35.107 78.968 11.838 1.00 208.38 ? 146 ILE R CA 1 +ATOM 33451 C C . ILE R 1 146 ? 36.221 77.940 11.988 1.00 191.22 ? 146 ILE R C 1 +ATOM 33452 O O . ILE R 1 146 ? 37.398 78.300 11.947 1.00 224.32 ? 146 ILE R O 1 +ATOM 33453 C CB . ILE R 1 146 ? 34.895 79.300 10.334 1.00 194.82 ? 146 ILE R CB 1 +ATOM 33454 C CG1 . ILE R 1 146 ? 34.158 80.642 10.166 1.00 194.76 ? 146 ILE R CG1 1 +ATOM 33455 C CG2 . ILE R 1 146 ? 34.124 78.183 9.642 1.00 167.21 ? 146 ILE R CG2 1 +ATOM 33456 C CD1 . ILE R 1 146 ? 35.067 81.829 9.912 1.00 169.04 ? 146 ILE R CD1 1 +ATOM 33457 N N . GLY R 1 147 ? 35.870 76.665 12.162 1.00 135.13 ? 147 GLY R N 1 +ATOM 33458 C CA . GLY R 1 147 ? 36.900 75.647 12.391 1.00 145.74 ? 147 GLY R CA 1 +ATOM 33459 C C . GLY R 1 147 ? 36.578 74.246 11.904 1.00 135.09 ? 147 GLY R C 1 +ATOM 33460 O O . GLY R 1 147 ? 35.421 73.870 11.785 1.00 93.17 ? 147 GLY R O 1 +ATOM 33461 N N . ALA R 1 148 ? 37.626 73.471 11.633 1.00 160.85 ? 148 ALA R N 1 +ATOM 33462 C CA . ALA R 1 148 ? 37.475 72.051 11.330 1.00 146.67 ? 148 ALA R CA 1 +ATOM 33463 C C . ALA R 1 148 ? 38.688 71.269 11.809 1.00 165.40 ? 148 ALA R C 1 +ATOM 33464 O O . ALA R 1 148 ? 39.720 71.846 12.196 1.00 132.30 ? 148 ALA R O 1 +ATOM 33465 C CB . ALA R 1 148 ? 37.271 71.836 9.843 1.00 113.93 ? 148 ALA R CB 1 +ATOM 33466 N N . ASP R 1 149 ? 38.535 69.951 11.844 1.00 180.95 ? 149 ASP R N 1 +ATOM 33467 C CA . ASP R 1 149 ? 39.624 69.079 12.258 1.00 190.00 ? 149 ASP R CA 1 +ATOM 33468 C C . ASP R 1 149 ? 39.325 67.635 11.884 1.00 164.09 ? 149 ASP R C 1 +ATOM 33469 O O . ASP R 1 149 ? 38.169 67.215 11.892 1.00 89.92 ? 149 ASP R O 1 +ATOM 33470 C CB . ASP R 1 149 ? 39.901 69.205 13.772 1.00 197.72 ? 149 ASP R CB 1 +ATOM 33471 C CG . ASP R 1 149 ? 38.949 68.396 14.610 1.00 168.53 ? 149 ASP R CG 1 +ATOM 33472 O OD1 . ASP R 1 149 ? 37.799 68.840 14.769 1.00 168.42 ? 149 ASP R OD1 1 +ATOM 33473 O OD2 . ASP R 1 149 ? 39.367 67.353 15.140 1.00 122.20 ? 149 ASP R OD2 1 +ATOM 33474 N N . THR R 1 150 ? 40.375 66.885 11.565 1.00 174.40 ? 150 THR R N 1 +ATOM 33475 C CA . THR R 1 150 ? 40.269 65.436 11.515 1.00 171.84 ? 150 THR R CA 1 +ATOM 33476 C C . THR R 1 150 ? 41.284 64.797 12.456 1.00 198.35 ? 150 THR R C 1 +ATOM 33477 O O . THR R 1 150 ? 42.309 65.391 12.801 1.00 163.00 ? 150 THR R O 1 +ATOM 33478 C CB . THR R 1 150 ? 40.483 64.873 10.098 1.00 147.60 ? 150 THR R CB 1 +ATOM 33479 O OG1 . THR R 1 150 ? 41.786 65.244 9.633 1.00 157.86 ? 150 THR R OG1 1 +ATOM 33480 C CG2 . THR R 1 150 ? 39.424 65.387 9.151 1.00 125.59 ? 150 THR R CG2 1 +ATOM 33481 N N . GLN R 1 151 ? 40.955 63.593 12.901 1.00 216.33 ? 151 GLN R N 1 +ATOM 33482 C CA . GLN R 1 151 ? 41.852 62.786 13.703 1.00 195.76 ? 151 GLN R CA 1 +ATOM 33483 C C . GLN R 1 151 ? 41.772 61.350 13.221 1.00 168.77 ? 151 GLN R C 1 +ATOM 33484 O O . GLN R 1 151 ? 40.712 60.904 12.819 1.00 110.98 ? 151 GLN R O 1 +ATOM 33485 C CB . GLN R 1 151 ? 41.433 62.873 15.164 1.00 172.34 ? 151 GLN R CB 1 +ATOM 33486 C CG . GLN R 1 151 ? 41.750 64.213 15.789 1.00 163.35 ? 151 GLN R CG 1 +ATOM 33487 C CD . GLN R 1 151 ? 40.910 64.486 17.011 1.00 166.28 ? 151 GLN R CD 1 +ATOM 33488 O OE1 . GLN R 1 151 ? 40.673 63.583 17.809 1.00 185.20 ? 151 GLN R OE1 1 +ATOM 33489 N NE2 . GLN R 1 151 ? 40.446 65.724 17.161 1.00 162.25 ? 151 GLN R NE2 1 +ATOM 33490 N N . TYR R 1 152 ? 42.896 60.639 13.218 1.00 147.38 ? 152 TYR R N 1 +ATOM 33491 C CA . TYR R 1 152 ? 42.881 59.253 12.792 1.00 112.99 ? 152 TYR R CA 1 +ATOM 33492 C C . TYR R 1 152 ? 43.738 58.370 13.669 1.00 136.56 ? 152 TYR R C 1 +ATOM 33493 O O . TYR R 1 152 ? 44.751 58.811 14.219 1.00 154.01 ? 152 TYR R O 1 +ATOM 33494 C CB . TYR R 1 152 ? 43.334 59.142 11.353 1.00 103.89 ? 152 TYR R CB 1 +ATOM 33495 C CG . TYR R 1 152 ? 44.744 58.600 11.149 1.00 97.47 ? 152 TYR R CG 1 +ATOM 33496 C CD1 . TYR R 1 152 ? 45.867 59.319 11.520 1.00 78.23 ? 152 TYR R CD1 1 +ATOM 33497 C CD2 . TYR R 1 152 ? 44.941 57.417 10.444 1.00 98.13 ? 152 TYR R CD2 1 +ATOM 33498 C CE1 . TYR R 1 152 ? 47.134 58.834 11.261 1.00 80.63 ? 152 TYR R CE1 1 +ATOM 33499 C CE2 . TYR R 1 152 ? 46.218 56.966 10.105 1.00 71.64 ? 152 TYR R CE2 1 +ATOM 33500 C CZ . TYR R 1 152 ? 47.305 57.668 10.516 1.00 70.28 ? 152 TYR R CZ 1 +ATOM 33501 O OH . TYR R 1 152 ? 48.573 57.226 10.167 1.00 83.12 ? 152 TYR R OH 1 +ATOM 33502 N N . GLN R 1 153 ? 43.311 57.123 13.822 1.00 165.56 ? 153 GLN R N 1 +ATOM 33503 C CA . GLN R 1 153 ? 44.131 56.116 14.479 1.00 171.88 ? 153 GLN R CA 1 +ATOM 33504 C C . GLN R 1 153 ? 44.083 54.815 13.691 1.00 142.22 ? 153 GLN R C 1 +ATOM 33505 O O . GLN R 1 153 ? 43.113 54.554 12.976 1.00 125.32 ? 153 GLN R O 1 +ATOM 33506 C CB . GLN R 1 153 ? 43.641 55.895 15.914 1.00 187.80 ? 153 GLN R CB 1 +ATOM 33507 C CG . GLN R 1 153 ? 43.801 57.102 16.852 1.00 204.60 ? 153 GLN R CG 1 +ATOM 33508 C CD . GLN R 1 153 ? 43.180 56.836 18.237 1.00 218.55 ? 153 GLN R CD 1 +ATOM 33509 O OE1 . GLN R 1 153 ? 42.329 55.952 18.393 1.00 246.58 ? 153 GLN R OE1 1 +ATOM 33510 N NE2 . GLN R 1 153 ? 43.616 57.588 19.242 1.00 215.11 ? 153 GLN R NE2 1 +ATOM 33511 N N . LEU R 1 154 ? 45.134 54.010 13.810 1.00 112.41 ? 154 LEU R N 1 +ATOM 33512 C CA . LEU R 1 154 ? 45.098 52.687 13.223 1.00 115.22 ? 154 LEU R CA 1 +ATOM 33513 C C . LEU R 1 154 ? 45.804 51.624 14.063 1.00 147.61 ? 154 LEU R C 1 +ATOM 33514 O O . LEU R 1 154 ? 46.847 51.875 14.690 1.00 143.08 ? 154 LEU R O 1 +ATOM 33515 C CB . LEU R 1 154 ? 45.672 52.707 11.813 1.00 105.60 ? 154 LEU R CB 1 +ATOM 33516 C CG . LEU R 1 154 ? 47.191 52.886 11.714 1.00 119.76 ? 154 LEU R CG 1 +ATOM 33517 C CD1 . LEU R 1 154 ? 47.919 51.554 11.594 1.00 97.29 ? 154 LEU R CD1 1 +ATOM 33518 C CD2 . LEU R 1 154 ? 47.509 53.785 10.528 1.00 166.00 ? 154 LEU R CD2 1 +ATOM 33519 N N . ASP R 1 155 ? 45.254 50.408 13.972 1.00 176.85 ? 155 ASP R N 1 +ATOM 33520 C CA . ASP R 1 155 ? 45.610 49.261 14.819 1.00 125.45 ? 155 ASP R CA 1 +ATOM 33521 C C . ASP R 1 155 ? 46.118 48.124 13.924 1.00 87.20 ? 155 ASP R C 1 +ATOM 33522 O O . ASP R 1 155 ? 45.810 48.098 12.732 1.00 93.57 ? 155 ASP R O 1 +ATOM 33523 C CB . ASP R 1 155 ? 44.371 48.809 15.615 1.00 124.52 ? 155 ASP R CB 1 +ATOM 33524 C CG . ASP R 1 155 ? 43.624 49.977 16.267 1.00 145.34 ? 155 ASP R CG 1 +ATOM 33525 O OD1 . ASP R 1 155 ? 42.862 50.679 15.566 1.00 119.28 ? 155 ASP R OD1 1 +ATOM 33526 O OD2 . ASP R 1 155 ? 43.836 50.210 17.476 1.00 184.17 ? 155 ASP R OD2 1 +ATOM 33527 N N . GLN R 1 156 ? 46.850 47.179 14.492 1.00 66.84 ? 156 GLN R N 1 +ATOM 33528 C CA . GLN R 1 156 ? 47.309 46.008 13.736 1.00 71.66 ? 156 GLN R CA 1 +ATOM 33529 C C . GLN R 1 156 ? 46.675 44.676 14.228 1.00 88.65 ? 156 GLN R C 1 +ATOM 33530 O O . GLN R 1 156 ? 46.193 44.565 15.356 1.00 117.21 ? 156 GLN R O 1 +ATOM 33531 C CB . GLN R 1 156 ? 48.812 45.906 13.817 1.00 61.45 ? 156 GLN R CB 1 +ATOM 33532 C CG . GLN R 1 156 ? 49.426 44.915 12.858 1.00 65.42 ? 156 GLN R CG 1 +ATOM 33533 C CD . GLN R 1 156 ? 50.899 45.188 12.624 1.00 93.07 ? 156 GLN R CD 1 +ATOM 33534 O OE1 . GLN R 1 156 ? 51.505 46.056 13.277 1.00 125.00 ? 156 GLN R OE1 1 +ATOM 33535 N NE2 . GLN R 1 156 ? 51.496 44.460 11.684 1.00 112.10 ? 156 GLN R NE2 1 +ATOM 33536 N N . ILE R 1 157 ? 46.643 43.682 13.350 1.00 68.07 ? 157 ILE R N 1 +ATOM 33537 C CA . ILE R 1 157 ? 46.135 42.377 13.677 1.00 61.36 ? 157 ILE R CA 1 +ATOM 33538 C C . ILE R 1 157 ? 46.886 41.361 12.803 1.00 54.72 ? 157 ILE R C 1 +ATOM 33539 O O . ILE R 1 157 ? 47.097 41.586 11.626 1.00 56.71 ? 157 ILE R O 1 +ATOM 33540 C CB . ILE R 1 157 ? 44.587 42.302 13.475 1.00 68.29 ? 157 ILE R CB 1 +ATOM 33541 C CG1 . ILE R 1 157 ? 43.965 41.175 14.338 1.00 92.83 ? 157 ILE R CG1 1 +ATOM 33542 C CG2 . ILE R 1 157 ? 44.239 42.053 12.021 1.00 64.53 ? 157 ILE R CG2 1 +ATOM 33543 C CD1 . ILE R 1 157 ? 42.437 41.140 14.365 1.00 64.71 ? 157 ILE R CD1 1 +ATOM 33544 N N . ALA R 1 158 ? 47.261 40.229 13.372 1.00 67.58 ? 158 ALA R N 1 +ATOM 33545 C CA . ALA R 1 158 ? 47.995 39.234 12.611 1.00 94.01 ? 158 ALA R CA 1 +ATOM 33546 C C . ALA R 1 158 ? 47.450 37.851 12.869 1.00 83.97 ? 158 ALA R C 1 +ATOM 33547 O O . ALA R 1 158 ? 46.880 37.576 13.933 1.00 129.38 ? 158 ALA R O 1 +ATOM 33548 C CB . ALA R 1 158 ? 49.487 39.289 12.940 1.00 124.92 ? 158 ALA R CB 1 +ATOM 33549 N N . VAL R 1 159 ? 47.653 36.971 11.899 1.00 58.30 ? 159 VAL R N 1 +ATOM 33550 C CA . VAL R 1 159 ? 47.055 35.660 11.954 1.00 66.41 ? 159 VAL R CA 1 +ATOM 33551 C C . VAL R 1 159 ? 48.045 34.646 11.418 1.00 60.78 ? 159 VAL R C 1 +ATOM 33552 O O . VAL R 1 159 ? 48.571 34.777 10.325 1.00 46.08 ? 159 VAL R O 1 +ATOM 33553 C CB . VAL R 1 159 ? 45.705 35.600 11.165 1.00 87.05 ? 159 VAL R CB 1 +ATOM 33554 C CG1 . VAL R 1 159 ? 45.342 34.169 10.786 1.00 89.54 ? 159 VAL R CG1 1 +ATOM 33555 C CG2 . VAL R 1 159 ? 44.554 36.232 11.959 1.00 82.73 ? 159 VAL R CG2 1 +ATOM 33556 N N . ASN R 1 160 ? 48.225 33.591 12.190 1.00 76.51 ? 160 ASN R N 1 +ATOM 33557 C CA . ASN R 1 160 ? 48.916 32.412 11.733 1.00 67.75 ? 160 ASN R CA 1 +ATOM 33558 C C . ASN R 1 160 ? 47.859 31.421 11.248 1.00 48.85 ? 160 ASN R C 1 +ATOM 33559 O O . ASN R 1 160 ? 46.940 31.069 11.984 1.00 40.60 ? 160 ASN R O 1 +ATOM 33560 C CB . ASN R 1 160 ? 49.770 31.847 12.895 1.00 67.09 ? 160 ASN R CB 1 +ATOM 33561 C CG . ASN R 1 160 ? 50.527 30.572 12.512 1.00 75.77 ? 160 ASN R CG 1 +ATOM 33562 O OD1 . ASN R 1 160 ? 49.949 29.599 12.037 1.00 81.17 ? 160 ASN R OD1 1 +ATOM 33563 N ND2 . ASN R 1 160 ? 51.799 30.515 12.871 1.00 113.43 ? 160 ASN R ND2 1 +ATOM 33564 N N . LEU R 1 161 ? 48.052 30.898 10.059 1.00 48.91 ? 161 LEU R N 1 +ATOM 33565 C CA . LEU R 1 161 ? 47.471 29.592 9.691 1.00 59.12 ? 161 LEU R CA 1 +ATOM 33566 C C . LEU R 1 161 ? 48.545 28.554 9.284 1.00 59.98 ? 161 LEU R C 1 +ATOM 33567 O O . LEU R 1 161 ? 49.608 28.912 8.780 1.00 75.14 ? 161 LEU R O 1 +ATOM 33568 C CB . LEU R 1 161 ? 46.535 29.791 8.530 1.00 60.60 ? 161 LEU R CB 1 +ATOM 33569 C CG . LEU R 1 161 ? 45.347 30.691 8.834 1.00 78.39 ? 161 LEU R CG 1 +ATOM 33570 C CD1 . LEU R 1 161 ? 44.611 30.982 7.542 1.00 110.85 ? 161 LEU R CD1 1 +ATOM 33571 C CD2 . LEU R 1 161 ? 44.444 30.015 9.833 1.00 84.61 ? 161 LEU R CD2 1 +ATOM 33572 N N . ARG R 1 162 ? 48.288 27.279 9.522 1.00 49.85 ? 162 ARG R N 1 +ATOM 33573 C CA . ARG R 1 162 ? 49.266 26.275 9.176 1.00 70.07 ? 162 ARG R CA 1 +ATOM 33574 C C . ARG R 1 162 ? 48.671 24.902 8.883 1.00 75.72 ? 162 ARG R C 1 +ATOM 33575 O O . ARG R 1 162 ? 47.873 24.376 9.663 1.00 76.13 ? 162 ARG R O 1 +ATOM 33576 C CB . ARG R 1 162 ? 50.377 26.186 10.244 1.00 102.50 ? 162 ARG R CB 1 +ATOM 33577 C CG . ARG R 1 162 ? 49.979 25.741 11.653 1.00 124.03 ? 162 ARG R CG 1 +ATOM 33578 C CD . ARG R 1 162 ? 51.223 25.311 12.455 1.00 95.81 ? 162 ARG R CD 1 +ATOM 33579 N NE . ARG R 1 162 ? 50.924 24.694 13.747 1.00 90.20 ? 162 ARG R NE 1 +ATOM 33580 C CZ . ARG R 1 162 ? 50.587 25.377 14.850 1.00 119.51 ? 162 ARG R CZ 1 +ATOM 33581 N NH1 . ARG R 1 162 ? 50.483 26.714 14.835 1.00 139.00 ? 162 ARG R NH1 1 +ATOM 33582 N NH2 . ARG R 1 162 ? 50.311 24.723 15.973 1.00 101.32 ? 162 ARG R NH2 1 +ATOM 33583 N N . VAL R 1 163 ? 49.134 24.311 7.775 1.00 78.70 ? 163 VAL R N 1 +ATOM 33584 C CA . VAL R 1 163 ? 48.714 22.977 7.321 1.00 85.20 ? 163 VAL R CA 1 +ATOM 33585 C C . VAL R 1 163 ? 49.559 21.898 7.932 1.00 87.29 ? 163 VAL R C 1 +ATOM 33586 O O . VAL R 1 163 ? 50.777 21.913 7.799 1.00 89.84 ? 163 VAL R O 1 +ATOM 33587 C CB . VAL R 1 163 ? 48.890 22.780 5.817 1.00 79.34 ? 163 VAL R CB 1 +ATOM 33588 C CG1 . VAL R 1 163 ? 48.470 21.364 5.428 1.00 60.34 ? 163 VAL R CG1 1 +ATOM 33589 C CG2 . VAL R 1 163 ? 48.107 23.863 5.064 1.00 103.19 ? 163 VAL R CG2 1 +ATOM 33590 N N . VAL R 1 164 ? 48.892 20.983 8.632 1.00 85.03 ? 164 VAL R N 1 +ATOM 33591 C CA . VAL R 1 164 ? 49.545 19.899 9.324 1.00 87.42 ? 164 VAL R CA 1 +ATOM 33592 C C . VAL R 1 164 ? 49.126 18.630 8.644 1.00 69.86 ? 164 VAL R C 1 +ATOM 33593 O O . VAL R 1 164 ? 47.954 18.416 8.412 1.00 45.93 ? 164 VAL R O 1 +ATOM 33594 C CB . VAL R 1 164 ? 49.141 19.822 10.808 1.00 129.79 ? 164 VAL R CB 1 +ATOM 33595 C CG1 . VAL R 1 164 ? 49.811 18.627 11.480 1.00 148.51 ? 164 VAL R CG1 1 +ATOM 33596 C CG2 . VAL R 1 164 ? 49.530 21.103 11.535 1.00 166.72 ? 164 VAL R CG2 1 +ATOM 33597 N N . ASN R 1 165 ? 50.104 17.772 8.405 1.00 66.24 ? 165 ASN R N 1 +ATOM 33598 C CA . ASN R 1 165 ? 49.844 16.481 7.825 1.00 66.00 ? 165 ASN R CA 1 +ATOM 33599 C C . ASN R 1 165 ? 49.457 15.466 8.882 1.00 86.40 ? 165 ASN R C 1 +ATOM 33600 O O . ASN R 1 165 ? 50.255 15.150 9.789 1.00 122.53 ? 165 ASN R O 1 +ATOM 33601 C CB . ASN R 1 165 ? 51.066 15.955 7.102 1.00 77.22 ? 165 ASN R CB 1 +ATOM 33602 C CG . ASN R 1 165 ? 50.772 14.672 6.379 1.00 101.58 ? 165 ASN R CG 1 +ATOM 33603 O OD1 . ASN R 1 165 ? 49.601 14.369 6.106 1.00 127.68 ? 165 ASN R OD1 1 +ATOM 33604 N ND2 . ASN R 1 165 ? 51.822 14.020 5.890 1.00 134.60 ? 165 ASN R ND2 1 +ATOM 33605 N N . VAL R 1 166 ? 48.247 14.932 8.754 1.00 90.86 ? 166 VAL R N 1 +ATOM 33606 C CA . VAL R 1 166 ? 47.702 14.001 9.732 1.00 91.00 ? 166 VAL R CA 1 +ATOM 33607 C C . VAL R 1 166 ? 48.587 12.783 9.790 1.00 86.25 ? 166 VAL R C 1 +ATOM 33608 O O . VAL R 1 166 ? 48.798 12.232 10.879 1.00 139.68 ? 166 VAL R O 1 +ATOM 33609 C CB . VAL R 1 166 ? 46.252 13.595 9.378 1.00 106.84 ? 166 VAL R CB 1 +ATOM 33610 C CG1 . VAL R 1 166 ? 45.866 12.233 9.955 1.00 94.74 ? 166 VAL R CG1 1 +ATOM 33611 C CG2 . VAL R 1 166 ? 45.286 14.691 9.817 1.00 119.65 ? 166 VAL R CG2 1 +ATOM 33612 N N . SER R 1 167 ? 49.111 12.379 8.639 1.00 67.14 ? 167 SER R N 1 +ATOM 33613 C CA . SER R 1 167 ? 49.774 11.105 8.542 1.00 81.88 ? 167 SER R CA 1 +ATOM 33614 C C . SER R 1 167 ? 51.160 11.111 9.199 1.00 77.75 ? 167 SER R C 1 +ATOM 33615 O O . SER R 1 167 ? 51.739 10.039 9.446 1.00 68.07 ? 167 SER R O 1 +ATOM 33616 C CB . SER R 1 167 ? 49.872 10.700 7.079 1.00 105.26 ? 167 SER R CB 1 +ATOM 33617 O OG . SER R 1 167 ? 48.621 10.877 6.416 1.00 111.00 ? 167 SER R OG 1 +ATOM 33618 N N . THR R 1 168 ? 51.679 12.300 9.507 1.00 75.97 ? 168 THR R N 1 +ATOM 33619 C CA . THR R 1 168 ? 53.028 12.422 10.116 1.00 83.26 ? 168 THR R CA 1 +ATOM 33620 C C . THR R 1 168 ? 53.175 13.447 11.253 1.00 77.55 ? 168 THR R C 1 +ATOM 33621 O O . THR R 1 168 ? 53.923 13.251 12.217 1.00 94.19 ? 168 THR R O 1 +ATOM 33622 C CB . THR R 1 168 ? 54.040 12.839 9.068 1.00 93.31 ? 168 THR R CB 1 +ATOM 33623 O OG1 . THR R 1 168 ? 53.546 13.995 8.387 1.00 61.50 ? 168 THR R OG1 1 +ATOM 33624 C CG2 . THR R 1 168 ? 54.272 11.698 8.076 1.00 125.16 ? 168 THR R CG2 1 +ATOM 33625 N N . GLY R 1 169 ? 52.392 14.505 11.192 1.00 67.38 ? 169 GLY R N 1 +ATOM 33626 C CA . GLY R 1 169 ? 52.504 15.531 12.182 1.00 65.38 ? 169 GLY R CA 1 +ATOM 33627 C C . GLY R 1 169 ? 53.436 16.588 11.666 1.00 90.36 ? 169 GLY R C 1 +ATOM 33628 O O . GLY R 1 169 ? 53.544 17.666 12.260 1.00 130.58 ? 169 GLY R O 1 +ATOM 33629 N N . GLU R 1 170 ? 54.125 16.307 10.553 1.00 94.55 ? 170 GLU R N 1 +ATOM 33630 C CA . GLU R 1 170 ? 54.889 17.353 9.837 1.00 100.02 ? 170 GLU R CA 1 +ATOM 33631 C C . GLU R 1 170 ? 53.941 18.509 9.519 1.00 80.29 ? 170 GLU R C 1 +ATOM 33632 O O . GLU R 1 170 ? 52.868 18.301 8.999 1.00 89.16 ? 170 GLU R O 1 +ATOM 33633 C CB . GLU R 1 170 ? 55.508 16.822 8.530 1.00 89.29 ? 170 GLU R CB 1 +ATOM 33634 C CG . GLU R 1 170 ? 56.752 15.974 8.731 1.00 84.37 ? 170 GLU R CG 1 +ATOM 33635 C CD . GLU R 1 170 ? 56.865 14.807 7.774 1.00 92.84 ? 170 GLU R CD 1 +ATOM 33636 O OE1 . GLU R 1 170 ? 55.878 14.525 7.037 1.00 129.55 ? 170 GLU R OE1 1 +ATOM 33637 O OE2 . GLU R 1 170 ? 57.932 14.142 7.774 1.00 78.82 ? 170 GLU R OE2 1 +ATOM 33638 N N . ILE R 1 171 ? 54.298 19.705 9.931 1.00 61.54 ? 171 ILE R N 1 +ATOM 33639 C CA . ILE R 1 171 ? 53.648 20.840 9.402 1.00 69.57 ? 171 ILE R CA 1 +ATOM 33640 C C . ILE R 1 171 ? 54.045 20.955 7.924 1.00 74.13 ? 171 ILE R C 1 +ATOM 33641 O O . ILE R 1 171 ? 55.233 21.033 7.606 1.00 80.92 ? 171 ILE R O 1 +ATOM 33642 C CB . ILE R 1 171 ? 54.035 22.086 10.202 1.00 87.13 ? 171 ILE R CB 1 +ATOM 33643 C CG1 . ILE R 1 171 ? 53.410 22.018 11.588 1.00 82.82 ? 171 ILE R CG1 1 +ATOM 33644 C CG2 . ILE R 1 171 ? 53.590 23.344 9.460 1.00 101.74 ? 171 ILE R CG2 1 +ATOM 33645 C CD1 . ILE R 1 171 ? 54.037 22.980 12.561 1.00 104.53 ? 171 ILE R CD1 1 +ATOM 33646 N N . LEU R 1 172 ? 53.063 21.050 7.033 1.00 102.13 ? 172 LEU R N 1 +ATOM 33647 C CA . LEU R 1 172 ? 53.348 21.160 5.601 1.00 126.65 ? 172 LEU R CA 1 +ATOM 33648 C C . LEU R 1 172 ? 53.397 22.613 5.092 1.00 156.17 ? 172 LEU R C 1 +ATOM 33649 O O . LEU R 1 172 ? 53.862 22.903 3.972 1.00 148.41 ? 172 LEU R O 1 +ATOM 33650 C CB . LEU R 1 172 ? 52.325 20.377 4.779 1.00 126.66 ? 172 LEU R CB 1 +ATOM 33651 C CG . LEU R 1 172 ? 52.570 18.891 4.488 1.00 140.95 ? 172 LEU R CG 1 +ATOM 33652 C CD1 . LEU R 1 172 ? 53.451 18.319 5.581 1.00 103.16 ? 172 LEU R CD1 1 +ATOM 33653 C CD2 . LEU R 1 172 ? 51.336 18.030 4.218 1.00 173.06 ? 172 LEU R CD2 1 +ATOM 33654 N N . SER R 1 173 ? 52.924 23.537 5.921 1.00 179.17 ? 173 SER R N 1 +ATOM 33655 C CA . SER R 1 173 ? 52.978 24.961 5.576 1.00 165.59 ? 173 SER R CA 1 +ATOM 33656 C C . SER R 1 173 ? 52.603 25.844 6.753 1.00 139.39 ? 173 SER R C 1 +ATOM 33657 O O . SER R 1 173 ? 51.597 25.594 7.426 1.00 185.97 ? 173 SER R O 1 +ATOM 33658 C CB . SER R 1 173 ? 51.998 25.251 4.444 1.00 200.02 ? 173 SER R CB 1 +ATOM 33659 O OG . SER R 1 173 ? 51.766 26.635 4.329 1.00 188.40 ? 173 SER R OG 1 +ATOM 33660 N N . SER R 1 174 ? 53.387 26.888 6.990 1.00 91.42 ? 174 SER R N 1 +ATOM 33661 C CA . SER R 1 174 ? 52.992 27.913 7.966 1.00 104.13 ? 174 SER R CA 1 +ATOM 33662 C C . SER R 1 174 ? 52.976 29.238 7.267 1.00 116.60 ? 174 SER R C 1 +ATOM 33663 O O . SER R 1 174 ? 53.905 29.551 6.509 1.00 170.44 ? 174 SER R O 1 +ATOM 33664 C CB . SER R 1 174 ? 53.961 27.968 9.180 1.00 104.13 ? 174 SER R CB 1 +ATOM 33665 O OG . SER R 1 174 ? 53.478 28.810 10.239 1.00 57.07 ? 174 SER R OG 1 +ATOM 33666 N N . VAL R 1 175 ? 51.959 30.042 7.553 1.00 95.87 ? 175 VAL R N 1 +ATOM 33667 C CA . VAL R 1 175 ? 51.859 31.380 6.967 1.00 98.89 ? 175 VAL R CA 1 +ATOM 33668 C C . VAL R 1 175 ? 51.407 32.421 7.982 1.00 107.59 ? 175 VAL R C 1 +ATOM 33669 O O . VAL R 1 175 ? 50.599 32.143 8.860 1.00 125.26 ? 175 VAL R O 1 +ATOM 33670 C CB . VAL R 1 175 ? 50.884 31.411 5.771 1.00 113.58 ? 175 VAL R CB 1 +ATOM 33671 C CG1 . VAL R 1 175 ? 51.393 30.516 4.648 1.00 140.47 ? 175 VAL R CG1 1 +ATOM 33672 C CG2 . VAL R 1 175 ? 49.492 30.968 6.178 1.00 108.13 ? 175 VAL R CG2 1 +ATOM 33673 N N . ASN R 1 176 ? 51.909 33.639 7.818 1.00 135.03 ? 176 ASN R N 1 +ATOM 33674 C CA . ASN R 1 176 ? 51.714 34.708 8.793 1.00 157.43 ? 176 ASN R CA 1 +ATOM 33675 C C . ASN R 1 176 ? 51.185 35.991 8.130 1.00 109.66 ? 176 ASN R C 1 +ATOM 33676 O O . ASN R 1 176 ? 51.980 36.821 7.720 1.00 135.54 ? 176 ASN R O 1 +ATOM 33677 C CB . ASN R 1 176 ? 53.069 34.975 9.515 1.00 174.18 ? 176 ASN R CB 1 +ATOM 33678 C CG . ASN R 1 176 ? 53.204 34.198 10.840 1.00 138.43 ? 176 ASN R CG 1 +ATOM 33679 O OD1 . ASN R 1 176 ? 52.379 33.337 11.091 1.00 186.98 ? 176 ASN R OD1 1 +ATOM 33680 N ND2 . ASN R 1 176 ? 54.176 34.548 11.716 1.00 84.64 ? 176 ASN R ND2 1 +ATOM 33681 N N . THR R 1 177 ? 49.877 36.192 8.143 1.00 77.94 ? 177 THR R N 1 +ATOM 33682 C CA . THR R 1 177 ? 49.283 37.374 7.534 1.00 89.41 ? 177 THR R CA 1 +ATOM 33683 C C . THR R 1 177 ? 49.002 38.487 8.544 1.00 110.64 ? 177 THR R C 1 +ATOM 33684 O O . THR R 1 177 ? 48.920 38.232 9.741 1.00 137.29 ? 177 THR R O 1 +ATOM 33685 C CB . THR R 1 177 ? 47.979 37.026 6.800 1.00 98.40 ? 177 THR R CB 1 +ATOM 33686 O OG1 . THR R 1 177 ? 46.958 36.692 7.740 1.00 100.00 ? 177 THR R OG1 1 +ATOM 33687 C CG2 . THR R 1 177 ? 48.188 35.828 5.859 1.00 129.65 ? 177 THR R CG2 1 +ATOM 33688 N N . SER R 1 178 ? 48.825 39.713 8.047 1.00 141.68 ? 178 SER R N 1 +ATOM 33689 C CA . SER R 1 178 ? 48.628 40.904 8.896 1.00 128.88 ? 178 SER R CA 1 +ATOM 33690 C C . SER R 1 178 ? 47.745 41.948 8.216 1.00 107.70 ? 178 SER R C 1 +ATOM 33691 O O . SER R 1 178 ? 47.647 42.004 6.997 1.00 140.76 ? 178 SER R O 1 +ATOM 33692 C CB . SER R 1 178 ? 49.967 41.562 9.243 1.00 103.43 ? 178 SER R CB 1 +ATOM 33693 O OG . SER R 1 178 ? 49.759 42.856 9.795 1.00 92.66 ? 178 SER R OG 1 +ATOM 33694 N N . LYS R 1 179 ? 47.080 42.761 9.016 1.00 99.35 ? 179 LYS R N 1 +ATOM 33695 C CA . LYS R 1 179 ? 46.077 43.666 8.496 1.00 115.83 ? 179 LYS R CA 1 +ATOM 33696 C C . LYS R 1 179 ? 45.881 44.840 9.441 1.00 133.96 ? 179 LYS R C 1 +ATOM 33697 O O . LYS R 1 179 ? 45.934 44.696 10.671 1.00 221.10 ? 179 LYS R O 1 +ATOM 33698 C CB . LYS R 1 179 ? 44.757 42.912 8.284 1.00 137.30 ? 179 LYS R CB 1 +ATOM 33699 C CG . LYS R 1 179 ? 43.966 43.364 7.066 1.00 141.22 ? 179 LYS R CG 1 +ATOM 33700 C CD . LYS R 1 179 ? 42.938 44.409 7.457 1.00 109.44 ? 179 LYS R CD 1 +ATOM 33701 C CE . LYS R 1 179 ? 42.283 44.972 6.220 1.00 108.18 ? 179 LYS R CE 1 +ATOM 33702 N NZ . LYS R 1 179 ? 41.506 46.192 6.542 1.00 111.71 ? 179 LYS R NZ 1 +ATOM 33703 N N . THR R 1 180 ? 45.634 46.000 8.863 1.00 107.67 ? 180 THR R N 1 +ATOM 33704 C CA . THR R 1 180 ? 45.518 47.218 9.631 1.00 118.65 ? 180 THR R CA 1 +ATOM 33705 C C . THR R 1 180 ? 44.050 47.682 9.721 1.00 115.95 ? 180 THR R C 1 +ATOM 33706 O O . THR R 1 180 ? 43.324 47.742 8.719 1.00 129.48 ? 180 THR R O 1 +ATOM 33707 C CB . THR R 1 180 ? 46.413 48.335 9.058 1.00 161.06 ? 180 THR R CB 1 +ATOM 33708 O OG1 . THR R 1 180 ? 45.886 49.622 9.421 1.00 225.78 ? 180 THR R OG1 1 +ATOM 33709 C CG2 . THR R 1 180 ? 46.501 48.241 7.537 1.00 194.91 ? 180 THR R CG2 1 +ATOM 33710 N N . ILE R 1 181 ? 43.638 48.062 10.926 1.00 129.25 ? 181 ILE R N 1 +ATOM 33711 C CA . ILE R 1 181 ? 42.280 48.573 11.169 1.00 151.03 ? 181 ILE R CA 1 +ATOM 33712 C C . ILE R 1 181 ? 42.281 50.111 11.263 1.00 159.12 ? 181 ILE R C 1 +ATOM 33713 O O . ILE R 1 181 ? 42.903 50.680 12.153 1.00 137.78 ? 181 ILE R O 1 +ATOM 33714 C CB . ILE R 1 181 ? 41.666 47.961 12.458 1.00 141.23 ? 181 ILE R CB 1 +ATOM 33715 C CG1 . ILE R 1 181 ? 41.767 46.433 12.425 1.00 145.95 ? 181 ILE R CG1 1 +ATOM 33716 C CG2 . ILE R 1 181 ? 40.208 48.363 12.636 1.00 111.26 ? 181 ILE R CG2 1 +ATOM 33717 C CD1 . ILE R 1 181 ? 42.597 45.855 13.553 1.00 160.62 ? 181 ILE R CD1 1 +ATOM 33718 N N . LEU R 1 182 ? 41.563 50.760 10.343 1.00 191.17 ? 182 LEU R N 1 +ATOM 33719 C CA . LEU R 1 182 ? 41.503 52.226 10.251 1.00 179.18 ? 182 LEU R CA 1 +ATOM 33720 C C . LEU R 1 182 ? 40.326 52.855 11.010 1.00 147.39 ? 182 LEU R C 1 +ATOM 33721 O O . LEU R 1 182 ? 39.190 52.377 10.943 1.00 78.74 ? 182 LEU R O 1 +ATOM 33722 C CB . LEU R 1 182 ? 41.419 52.653 8.783 1.00 191.69 ? 182 LEU R CB 1 +ATOM 33723 C CG . LEU R 1 182 ? 41.337 54.160 8.531 1.00 185.34 ? 182 LEU R CG 1 +ATOM 33724 C CD1 . LEU R 1 182 ? 42.568 54.905 9.035 1.00 146.81 ? 182 LEU R CD1 1 +ATOM 33725 C CD2 . LEU R 1 182 ? 41.113 54.383 7.047 1.00 199.31 ? 182 LEU R CD2 1 +ATOM 33726 N N . SER R 1 183 ? 40.612 53.974 11.665 1.00 150.44 ? 183 SER R N 1 +ATOM 33727 C CA . SER R 1 183 ? 39.588 54.771 12.321 1.00 165.62 ? 183 SER R CA 1 +ATOM 33728 C C . SER R 1 183 ? 39.857 56.260 12.092 1.00 164.27 ? 183 SER R C 1 +ATOM 33729 O O . SER R 1 183 ? 41.012 56.697 12.128 1.00 171.07 ? 183 SER R O 1 +ATOM 33730 C CB . SER R 1 183 ? 39.575 54.466 13.823 1.00 205.27 ? 183 SER R CB 1 +ATOM 33731 O OG . SER R 1 183 ? 39.809 53.086 14.073 1.00 242.09 ? 183 SER R OG 1 +ATOM 33732 N N . TYR R 1 184 ? 38.796 57.040 11.878 1.00 154.24 ? 184 TYR R N 1 +ATOM 33733 C CA . TYR R 1 184 ? 38.929 58.501 11.720 1.00 126.25 ? 184 TYR R CA 1 +ATOM 33734 C C . TYR R 1 184 ? 37.679 59.318 12.103 1.00 109.09 ? 184 TYR R C 1 +ATOM 33735 O O . TYR R 1 184 ? 36.550 58.806 12.167 1.00 65.21 ? 184 TYR R O 1 +ATOM 33736 C CB . TYR R 1 184 ? 39.360 58.880 10.298 1.00 95.58 ? 184 TYR R CB 1 +ATOM 33737 C CG . TYR R 1 184 ? 38.411 58.454 9.220 1.00 93.89 ? 184 TYR R CG 1 +ATOM 33738 C CD1 . TYR R 1 184 ? 37.257 59.183 8.943 1.00 92.31 ? 184 TYR R CD1 1 +ATOM 33739 C CD2 . TYR R 1 184 ? 38.622 57.272 8.522 1.00 115.59 ? 184 TYR R CD2 1 +ATOM 33740 C CE1 . TYR R 1 184 ? 36.361 58.772 7.972 1.00 118.32 ? 184 TYR R CE1 1 +ATOM 33741 C CE2 . TYR R 1 184 ? 37.712 56.830 7.580 1.00 145.06 ? 184 TYR R CE2 1 +ATOM 33742 C CZ . TYR R 1 184 ? 36.596 57.598 7.287 1.00 141.32 ? 184 TYR R CZ 1 +ATOM 33743 O OH . TYR R 1 184 ? 35.674 57.130 6.365 1.00 141.94 ? 184 TYR R OH 1 +ATOM 33744 N N . GLU R 1 185 ? 37.949 60.571 12.455 1.00 109.92 ? 185 GLU R N 1 +ATOM 33745 C CA . GLU R 1 185 ? 36.971 61.452 13.043 1.00 124.09 ? 185 GLU R CA 1 +ATOM 33746 C C . GLU R 1 185 ? 37.075 62.829 12.435 1.00 146.86 ? 185 GLU R C 1 +ATOM 33747 O O . GLU R 1 185 ? 38.051 63.539 12.635 1.00 145.16 ? 185 GLU R O 1 +ATOM 33748 C CB . GLU R 1 185 ? 37.186 61.486 14.558 1.00 156.87 ? 185 GLU R CB 1 +ATOM 33749 C CG . GLU R 1 185 ? 36.404 62.522 15.341 1.00 164.39 ? 185 GLU R CG 1 +ATOM 33750 C CD . GLU R 1 185 ? 36.516 62.291 16.846 1.00 165.12 ? 185 GLU R CD 1 +ATOM 33751 O OE1 . GLU R 1 185 ? 37.141 61.292 17.261 1.00 152.10 ? 185 GLU R OE1 1 +ATOM 33752 O OE2 . GLU R 1 185 ? 35.954 63.089 17.618 1.00 145.26 ? 185 GLU R OE2 1 +ATOM 33753 N N . VAL R 1 186 ? 36.080 63.169 11.624 1.00 169.79 ? 186 VAL R N 1 +ATOM 33754 C CA . VAL R 1 186 ? 36.016 64.459 10.949 1.00 163.53 ? 186 VAL R CA 1 +ATOM 33755 C C . VAL R 1 186 ? 35.015 65.365 11.665 1.00 144.62 ? 186 VAL R C 1 +ATOM 33756 O O . VAL R 1 186 ? 33.951 64.912 12.084 1.00 91.35 ? 186 VAL R O 1 +ATOM 33757 C CB . VAL R 1 186 ? 35.601 64.297 9.472 1.00 162.74 ? 186 VAL R CB 1 +ATOM 33758 C CG1 . VAL R 1 186 ? 35.737 65.619 8.736 1.00 191.90 ? 186 VAL R CG1 1 +ATOM 33759 C CG2 . VAL R 1 186 ? 36.442 63.230 8.789 1.00 166.52 ? 186 VAL R CG2 1 +ATOM 33760 N N . GLN R 1 187 ? 35.378 66.636 11.825 1.00 160.87 ? 187 GLN R N 1 +ATOM 33761 C CA . GLN R 1 187 ? 34.544 67.577 12.568 1.00 162.14 ? 187 GLN R CA 1 +ATOM 33762 C C . GLN R 1 187 ? 34.676 68.980 12.013 1.00 173.31 ? 187 GLN R C 1 +ATOM 33763 O O . GLN R 1 187 ? 35.784 69.434 11.719 1.00 166.50 ? 187 GLN R O 1 +ATOM 33764 C CB . GLN R 1 187 ? 34.962 67.589 14.043 1.00 156.97 ? 187 GLN R CB 1 +ATOM 33765 C CG . GLN R 1 187 ? 34.313 66.531 14.912 1.00 159.64 ? 187 GLN R CG 1 +ATOM 33766 C CD . GLN R 1 187 ? 35.092 66.274 16.187 1.00 171.47 ? 187 GLN R CD 1 +ATOM 33767 O OE1 . GLN R 1 187 ? 35.648 67.198 16.781 1.00 161.07 ? 187 GLN R OE1 1 +ATOM 33768 N NE2 . GLN R 1 187 ? 35.171 65.004 16.594 1.00 169.55 ? 187 GLN R NE2 1 +ATOM 33769 N N . ALA R 1 188 ? 33.547 69.679 11.924 1.00 157.56 ? 188 ALA R N 1 +ATOM 33770 C CA . ALA R 1 188 ? 33.548 71.076 11.504 1.00 137.91 ? 188 ALA R CA 1 +ATOM 33771 C C . ALA R 1 188 ? 32.516 71.882 12.288 1.00 127.22 ? 188 ALA R C 1 +ATOM 33772 O O . ALA R 1 188 ? 31.437 71.393 12.580 1.00 99.47 ? 188 ALA R O 1 +ATOM 33773 C CB . ALA R 1 188 ? 33.284 71.172 10.013 1.00 128.70 ? 188 ALA R CB 1 +ATOM 33774 N N . GLY R 1 189 ? 32.873 73.108 12.656 1.00 135.92 ? 189 GLY R N 1 +ATOM 33775 C CA . GLY R 1 189 ? 31.989 73.957 13.443 1.00 149.71 ? 189 GLY R CA 1 +ATOM 33776 C C . GLY R 1 189 ? 32.117 75.427 13.087 1.00 173.83 ? 189 GLY R C 1 +ATOM 33777 O O . GLY R 1 189 ? 33.223 75.931 12.889 1.00 167.57 ? 189 GLY R O 1 +ATOM 33778 N N . VAL R 1 190 ? 30.982 76.120 13.032 1.00 182.76 ? 190 VAL R N 1 +ATOM 33779 C CA . VAL R 1 190 ? 30.956 77.561 12.778 1.00 180.65 ? 190 VAL R CA 1 +ATOM 33780 C C . VAL R 1 190 ? 30.400 78.310 13.992 1.00 177.98 ? 190 VAL R C 1 +ATOM 33781 O O . VAL R 1 190 ? 29.431 77.868 14.614 1.00 127.50 ? 190 VAL R O 1 +ATOM 33782 C CB . VAL R 1 190 ? 30.096 77.892 11.547 1.00 182.04 ? 190 VAL R CB 1 +ATOM 33783 C CG1 . VAL R 1 190 ? 30.287 79.343 11.147 1.00 170.91 ? 190 VAL R CG1 1 +ATOM 33784 C CG2 . VAL R 1 190 ? 30.431 76.953 10.385 1.00 183.03 ? 190 VAL R CG2 1 +ATOM 33785 N N . PHE R 1 191 ? 31.055 79.408 14.368 1.00 205.91 ? 191 PHE R N 1 +ATOM 33786 C CA . PHE R 1 191 ? 30.766 80.076 15.643 1.00 234.41 ? 191 PHE R CA 1 +ATOM 33787 C C . PHE R 1 191 ? 30.648 81.582 15.432 1.00 199.51 ? 191 PHE R C 1 +ATOM 33788 O O . PHE R 1 191 ? 31.527 82.181 14.810 1.00 192.47 ? 191 PHE R O 1 +ATOM 33789 C CB . PHE R 1 191 ? 31.861 79.754 16.684 1.00 243.32 ? 191 PHE R CB 1 +ATOM 33790 C CG . PHE R 1 191 ? 31.425 79.951 18.115 1.00 225.43 ? 191 PHE R CG 1 +ATOM 33791 C CD1 . PHE R 1 191 ? 31.236 81.230 18.628 1.00 190.71 ? 191 PHE R CD1 1 +ATOM 33792 C CD2 . PHE R 1 191 ? 31.223 78.858 18.952 1.00 204.47 ? 191 PHE R CD2 1 +ATOM 33793 C CE1 . PHE R 1 191 ? 30.854 81.416 19.945 1.00 167.41 ? 191 PHE R CE1 1 +ATOM 33794 C CE2 . PHE R 1 191 ? 30.825 79.039 20.265 1.00 200.57 ? 191 PHE R CE2 1 +ATOM 33795 C CZ . PHE R 1 191 ? 30.650 80.320 20.765 1.00 179.71 ? 191 PHE R CZ 1 +ATOM 33796 N N . LEU R 1 200 ? 25.339 82.653 17.178 1.00 184.91 ? 200 LEU R N 1 +ATOM 33797 C CA . LEU R 1 200 ? 25.320 81.577 16.186 1.00 215.34 ? 200 LEU R CA 1 +ATOM 33798 C C . LEU R 1 200 ? 26.422 80.558 16.441 1.00 217.68 ? 200 LEU R C 1 +ATOM 33799 O O . LEU R 1 200 ? 27.609 80.862 16.283 1.00 182.88 ? 200 LEU R O 1 +ATOM 33800 C CB . LEU R 1 200 ? 25.475 82.115 14.755 1.00 209.28 ? 200 LEU R CB 1 +ATOM 33801 C CG . LEU R 1 200 ? 25.657 81.021 13.681 1.00 179.22 ? 200 LEU R CG 1 +ATOM 33802 C CD1 . LEU R 1 200 ? 24.343 80.785 12.951 1.00 158.60 ? 200 LEU R CD1 1 +ATOM 33803 C CD2 . LEU R 1 200 ? 26.790 81.323 12.700 1.00 164.28 ? 200 LEU R CD2 1 +ATOM 33804 N N . GLU R 1 201 ? 26.016 79.343 16.806 1.00 207.54 ? 201 GLU R N 1 +ATOM 33805 C CA . GLU R 1 201 ? 26.882 78.175 16.701 1.00 174.51 ? 201 GLU R CA 1 +ATOM 33806 C C . GLU R 1 201 ? 26.262 77.132 15.783 1.00 139.90 ? 201 GLU R C 1 +ATOM 33807 O O . GLU R 1 201 ? 25.039 77.009 15.712 1.00 113.32 ? 201 GLU R O 1 +ATOM 33808 C CB . GLU R 1 201 ? 27.141 77.563 18.077 1.00 178.03 ? 201 GLU R CB 1 +ATOM 33809 C CG . GLU R 1 201 ? 28.377 76.673 18.104 1.00 182.36 ? 201 GLU R CG 1 +ATOM 33810 C CD . GLU R 1 201 ? 28.654 76.063 19.467 1.00 181.32 ? 201 GLU R CD 1 +ATOM 33811 O OE1 . GLU R 1 201 ? 28.666 76.809 20.470 1.00 202.56 ? 201 GLU R OE1 1 +ATOM 33812 O OE2 . GLU R 1 201 ? 28.856 74.833 19.536 1.00 171.14 ? 201 GLU R OE2 1 +ATOM 33813 N N . GLY R 1 202 ? 27.107 76.382 15.083 1.00 123.19 ? 202 GLY R N 1 +ATOM 33814 C CA . GLY R 1 202 ? 26.653 75.256 14.265 1.00 133.73 ? 202 GLY R CA 1 +ATOM 33815 C C . GLY R 1 202 ? 27.759 74.232 14.085 1.00 137.82 ? 202 GLY R C 1 +ATOM 33816 O O . GLY R 1 202 ? 28.863 74.569 13.652 1.00 118.77 ? 202 GLY R O 1 +ATOM 33817 N N . GLU R 1 203 ? 27.459 72.972 14.381 1.00 138.53 ? 203 GLU R N 1 +ATOM 33818 C CA . GLU R 1 203 ? 28.473 71.923 14.328 1.00 134.65 ? 203 GLU R CA 1 +ATOM 33819 C C . GLU R 1 203 ? 28.031 70.675 13.566 1.00 118.00 ? 203 GLU R C 1 +ATOM 33820 O O . GLU R 1 203 ? 26.909 70.191 13.728 1.00 71.58 ? 203 GLU R O 1 +ATOM 33821 C CB . GLU R 1 203 ? 28.886 71.537 15.746 1.00 158.92 ? 203 GLU R CB 1 +ATOM 33822 C CG . GLU R 1 203 ? 29.623 72.653 16.486 1.00 171.90 ? 203 GLU R CG 1 +ATOM 33823 C CD . GLU R 1 203 ? 30.138 72.254 17.865 1.00 207.90 ? 203 GLU R CD 1 +ATOM 33824 O OE1 . GLU R 1 203 ? 29.789 71.147 18.344 1.00 228.99 ? 203 GLU R OE1 1 +ATOM 33825 O OE2 . GLU R 1 203 ? 30.888 73.059 18.478 1.00 221.94 ? 203 GLU R OE2 1 +ATOM 33826 N N . VAL R 1 204 ? 28.945 70.150 12.757 1.00 135.38 ? 204 VAL R N 1 +ATOM 33827 C CA . VAL R 1 204 ? 28.794 68.851 12.110 1.00 170.75 ? 204 VAL R CA 1 +ATOM 33828 C C . VAL R 1 204 ? 29.974 67.959 12.499 1.00 191.78 ? 204 VAL R C 1 +ATOM 33829 O O . VAL R 1 204 ? 31.126 68.397 12.509 1.00 184.04 ? 204 VAL R O 1 +ATOM 33830 C CB . VAL R 1 204 ? 28.713 68.997 10.570 1.00 156.25 ? 204 VAL R CB 1 +ATOM 33831 C CG1 . VAL R 1 204 ? 28.926 67.663 9.861 1.00 146.70 ? 204 VAL R CG1 1 +ATOM 33832 C CG2 . VAL R 1 204 ? 27.370 69.596 10.182 1.00 148.03 ? 204 VAL R CG2 1 +ATOM 33833 N N . GLY R 1 205 ? 29.670 66.704 12.825 1.00 179.66 ? 205 GLY R N 1 +ATOM 33834 C CA . GLY R 1 205 ? 30.695 65.714 13.131 1.00 148.61 ? 205 GLY R CA 1 +ATOM 33835 C C . GLY R 1 205 ? 30.410 64.361 12.499 1.00 121.49 ? 205 GLY R C 1 +ATOM 33836 O O . GLY R 1 205 ? 29.256 64.000 12.286 1.00 81.33 ? 205 GLY R O 1 +ATOM 33837 N N . TYR R 1 206 ? 31.471 63.618 12.193 1.00 141.56 ? 206 TYR R N 1 +ATOM 33838 C CA . TYR R 1 206 ? 31.351 62.249 11.685 1.00 162.77 ? 206 TYR R CA 1 +ATOM 33839 C C . TYR R 1 206 ? 32.536 61.403 12.141 1.00 179.57 ? 206 TYR R C 1 +ATOM 33840 O O . TYR R 1 206 ? 33.664 61.883 12.158 1.00 193.06 ? 206 TYR R O 1 +ATOM 33841 C CB . TYR R 1 206 ? 31.294 62.249 10.153 1.00 173.75 ? 206 TYR R CB 1 +ATOM 33842 C CG . TYR R 1 206 ? 31.237 60.859 9.531 1.00 163.19 ? 206 TYR R CG 1 +ATOM 33843 C CD1 . TYR R 1 206 ? 30.058 60.103 9.552 1.00 125.24 ? 206 TYR R CD1 1 +ATOM 33844 C CD2 . TYR R 1 206 ? 32.359 60.311 8.913 1.00 152.63 ? 206 TYR R CD2 1 +ATOM 33845 C CE1 . TYR R 1 206 ? 29.991 58.854 8.962 1.00 89.55 ? 206 TYR R CE1 1 +ATOM 33846 C CE2 . TYR R 1 206 ? 32.301 59.068 8.316 1.00 129.89 ? 206 TYR R CE2 1 +ATOM 33847 C CZ . TYR R 1 206 ? 31.118 58.344 8.346 1.00 111.30 ? 206 TYR R CZ 1 +ATOM 33848 O OH . TYR R 1 206 ? 31.102 57.089 7.774 1.00 152.05 ? 206 TYR R OH 1 +ATOM 33849 N N . THR R 1 207 ? 32.287 60.135 12.462 1.00 152.79 ? 207 THR R N 1 +ATOM 33850 C CA . THR R 1 207 ? 33.364 59.221 12.848 1.00 145.57 ? 207 THR R CA 1 +ATOM 33851 C C . THR R 1 207 ? 33.180 57.835 12.219 1.00 118.32 ? 207 THR R C 1 +ATOM 33852 O O . THR R 1 207 ? 32.060 57.308 12.166 1.00 71.09 ? 207 THR R O 1 +ATOM 33853 C CB . THR R 1 207 ? 33.429 59.056 14.378 1.00 163.38 ? 207 THR R CB 1 +ATOM 33854 O OG1 . THR R 1 207 ? 32.197 58.498 14.855 1.00 167.25 ? 207 THR R OG1 1 +ATOM 33855 C CG2 . THR R 1 207 ? 33.649 60.387 15.058 1.00 163.65 ? 207 THR R CG2 1 +ATOM 33856 N N . SER R 1 208 ? 34.275 57.241 11.738 1.00 104.18 ? 208 SER R N 1 +ATOM 33857 C CA . SER R 1 208 ? 34.206 55.905 11.125 1.00 118.24 ? 208 SER R CA 1 +ATOM 33858 C C . SER R 1 208 ? 35.311 54.979 11.605 1.00 143.73 ? 208 SER R C 1 +ATOM 33859 O O . SER R 1 208 ? 36.497 55.308 11.515 1.00 107.32 ? 208 SER R O 1 +ATOM 33860 C CB . SER R 1 208 ? 34.245 55.992 9.597 1.00 124.39 ? 208 SER R CB 1 +ATOM 33861 O OG . SER R 1 208 ? 34.306 54.706 8.991 1.00 80.14 ? 208 SER R OG 1 +ATOM 33862 N N . ASN R 1 209 ? 34.896 53.806 12.075 1.00 179.67 ? 209 ASN R N 1 +ATOM 33863 C CA . ASN R 1 209 ? 35.811 52.735 12.449 1.00 185.99 ? 209 ASN R CA 1 +ATOM 33864 C C . ASN R 1 209 ? 35.654 51.553 11.520 1.00 177.19 ? 209 ASN R C 1 +ATOM 33865 O O . ASN R 1 209 ? 34.531 51.165 11.196 1.00 110.06 ? 209 ASN R O 1 +ATOM 33866 C CB . ASN R 1 209 ? 35.516 52.254 13.864 1.00 174.30 ? 209 ASN R CB 1 +ATOM 33867 C CG . ASN R 1 209 ? 35.882 53.275 14.906 1.00 160.18 ? 209 ASN R CG 1 +ATOM 33868 O OD1 . ASN R 1 209 ? 37.038 53.375 15.312 1.00 180.08 ? 209 ASN R OD1 1 +ATOM 33869 N ND2 . ASN R 1 209 ? 34.893 54.013 15.372 1.00 132.39 ? 209 ASN R ND2 1 +ATOM 33870 N N . GLU R 1 210 ? 36.777 50.966 11.114 1.00 171.08 ? 210 GLU R N 1 +ATOM 33871 C CA . GLU R 1 210 ? 36.738 49.682 10.432 1.00 141.95 ? 210 GLU R CA 1 +ATOM 33872 C C . GLU R 1 210 ? 36.295 48.647 11.442 1.00 141.61 ? 210 GLU R C 1 +ATOM 33873 O O . GLU R 1 210 ? 36.666 48.701 12.619 1.00 150.20 ? 210 GLU R O 1 +ATOM 33874 C CB . GLU R 1 210 ? 38.106 49.313 9.871 1.00 122.36 ? 210 GLU R CB 1 +ATOM 33875 C CG . GLU R 1 210 ? 38.086 48.742 8.464 1.00 116.29 ? 210 GLU R CG 1 +ATOM 33876 C CD . GLU R 1 210 ? 39.462 48.797 7.803 1.00 187.40 ? 210 GLU R CD 1 +ATOM 33877 O OE1 . GLU R 1 210 ? 40.323 49.667 8.156 1.00 292.39 ? 210 GLU R OE1 1 +ATOM 33878 O OE2 . GLU R 1 210 ? 39.716 47.948 6.924 1.00 258.02 ? 210 GLU R OE2 1 +ATOM 33879 N N . PRO R 1 211 ? 35.460 47.712 11.005 1.00 135.29 ? 211 PRO R N 1 +ATOM 33880 C CA . PRO R 1 211 ? 35.164 46.590 11.874 1.00 157.54 ? 211 PRO R CA 1 +ATOM 33881 C C . PRO R 1 211 ? 36.363 45.633 12.020 1.00 176.38 ? 211 PRO R C 1 +ATOM 33882 O O . PRO R 1 211 ? 36.900 45.142 11.024 1.00 162.24 ? 211 PRO R O 1 +ATOM 33883 C CB . PRO R 1 211 ? 33.989 45.900 11.166 1.00 182.74 ? 211 PRO R CB 1 +ATOM 33884 C CG . PRO R 1 211 ? 33.452 46.905 10.209 1.00 156.43 ? 211 PRO R CG 1 +ATOM 33885 C CD . PRO R 1 211 ? 34.652 47.688 9.783 1.00 149.59 ? 211 PRO R CD 1 +ATOM 33886 N N . VAL R 1 212 ? 36.757 45.367 13.264 1.00 159.27 ? 212 VAL R N 1 +ATOM 33887 C CA . VAL R 1 212 ? 37.857 44.443 13.553 1.00 121.65 ? 212 VAL R CA 1 +ATOM 33888 C C . VAL R 1 212 ? 37.459 43.066 13.028 1.00 99.74 ? 212 VAL R C 1 +ATOM 33889 O O . VAL R 1 212 ? 38.264 42.309 12.514 1.00 65.65 ? 212 VAL R O 1 +ATOM 33890 C CB . VAL R 1 212 ? 38.157 44.389 15.083 1.00 94.20 ? 212 VAL R CB 1 +ATOM 33891 C CG1 . VAL R 1 212 ? 39.397 43.533 15.344 1.00 74.89 ? 212 VAL R CG1 1 +ATOM 33892 C CG2 . VAL R 1 212 ? 38.336 45.792 15.659 1.00 101.51 ? 212 VAL R CG2 1 +ATOM 33893 N N . MET R 1 213 ? 36.214 42.725 13.327 1.00 93.75 ? 213 MET R N 1 +ATOM 33894 C CA . MET R 1 213 ? 35.512 41.590 12.771 1.00 87.16 ? 213 MET R CA 1 +ATOM 33895 C C . MET R 1 213 ? 35.926 41.333 11.332 1.00 76.95 ? 213 MET R C 1 +ATOM 33896 O O . MET R 1 213 ? 36.202 40.208 10.924 1.00 86.98 ? 213 MET R O 1 +ATOM 33897 C CB . MET R 1 213 ? 34.019 41.971 12.890 1.00 118.97 ? 213 MET R CB 1 +ATOM 33898 C CG . MET R 1 213 ? 32.966 40.977 12.467 1.00 135.75 ? 213 MET R CG 1 +ATOM 33899 S SD . MET R 1 213 ? 31.351 41.804 12.740 1.00 154.10 ? 213 MET R SD 1 +ATOM 33900 C CE . MET R 1 213 ? 30.905 41.941 11.025 1.00 165.50 ? 213 MET R CE 1 +ATOM 33901 N N . LEU R 1 214 ? 35.874 42.388 10.539 1.00 101.11 ? 214 LEU R N 1 +ATOM 33902 C CA . LEU R 1 214 ? 35.862 42.282 9.080 1.00 126.54 ? 214 LEU R CA 1 +ATOM 33903 C C . LEU R 1 214 ? 37.303 42.207 8.623 1.00 108.72 ? 214 LEU R C 1 +ATOM 33904 O O . LEU R 1 214 ? 37.605 41.599 7.589 1.00 101.13 ? 214 LEU R O 1 +ATOM 33905 C CB . LEU R 1 214 ? 35.144 43.499 8.446 1.00 132.64 ? 214 LEU R CB 1 +ATOM 33906 C CG . LEU R 1 214 ? 34.202 43.292 7.258 1.00 114.73 ? 214 LEU R CG 1 +ATOM 33907 C CD1 . LEU R 1 214 ? 33.042 42.347 7.589 1.00 117.02 ? 214 LEU R CD1 1 +ATOM 33908 C CD2 . LEU R 1 214 ? 33.673 44.639 6.772 1.00 107.55 ? 214 LEU R CD2 1 +ATOM 33909 N N . CYS R 1 215 ? 38.182 42.788 9.425 1.00 79.05 ? 215 CYS R N 1 +ATOM 33910 C CA . CYS R 1 215 ? 39.591 42.751 9.114 1.00 100.81 ? 215 CYS R CA 1 +ATOM 33911 C C . CYS R 1 215 ? 40.107 41.344 9.383 1.00 88.90 ? 215 CYS R C 1 +ATOM 33912 O O . CYS R 1 215 ? 41.021 40.828 8.675 1.00 74.86 ? 215 CYS R O 1 +ATOM 33913 C CB . CYS R 1 215 ? 40.340 43.775 9.970 1.00 127.32 ? 215 CYS R CB 1 +ATOM 33914 S SG . CYS R 1 215 ? 39.913 45.479 9.600 1.00 152.42 ? 215 CYS R SG 1 +ATOM 33915 N N . LEU R 1 216 ? 39.617 40.774 10.480 1.00 73.23 ? 216 LEU R N 1 +ATOM 33916 C CA . LEU R 1 216 ? 40.038 39.435 10.855 1.00 98.06 ? 216 LEU R CA 1 +ATOM 33917 C C . LEU R 1 216 ? 39.653 38.496 9.726 1.00 117.28 ? 216 LEU R C 1 +ATOM 33918 O O . LEU R 1 216 ? 40.460 37.693 9.259 1.00 104.28 ? 216 LEU R O 1 +ATOM 33919 C CB . LEU R 1 216 ? 39.364 39.017 12.159 1.00 117.54 ? 216 LEU R CB 1 +ATOM 33920 C CG . LEU R 1 216 ? 39.644 37.570 12.609 1.00 116.48 ? 216 LEU R CG 1 +ATOM 33921 C CD1 . LEU R 1 216 ? 41.135 37.272 12.783 1.00 92.52 ? 216 LEU R CD1 1 +ATOM 33922 C CD2 . LEU R 1 216 ? 38.888 37.265 13.902 1.00 92.98 ? 216 LEU R CD2 1 +ATOM 33923 N N . MET R 1 217 ? 38.427 38.662 9.240 1.00 150.96 ? 217 MET R N 1 +ATOM 33924 C CA . MET R 1 217 ? 37.905 37.794 8.186 1.00 152.28 ? 217 MET R CA 1 +ATOM 33925 C C . MET R 1 217 ? 38.731 37.920 6.907 1.00 114.92 ? 217 MET R C 1 +ATOM 33926 O O . MET R 1 217 ? 39.165 36.925 6.350 1.00 88.98 ? 217 MET R O 1 +ATOM 33927 C CB . MET R 1 217 ? 36.430 38.117 7.907 1.00 195.47 ? 217 MET R CB 1 +ATOM 33928 C CG . MET R 1 217 ? 35.558 36.881 7.753 1.00 213.72 ? 217 MET R CG 1 +ATOM 33929 S SD . MET R 1 217 ? 35.940 35.963 6.248 1.00 235.45 ? 217 MET R SD 1 +ATOM 33930 C CE . MET R 1 217 ? 35.001 34.455 6.477 1.00 272.88 ? 217 MET R CE 1 +ATOM 33931 N N . SER R 1 218 ? 39.005 39.162 6.512 1.00 90.12 ? 218 SER R N 1 +ATOM 33932 C CA . SER R 1 218 ? 39.840 39.445 5.360 1.00 94.40 ? 218 SER R CA 1 +ATOM 33933 C C . SER R 1 218 ? 41.209 38.747 5.453 1.00 109.58 ? 218 SER R C 1 +ATOM 33934 O O . SER R 1 218 ? 41.655 38.079 4.517 1.00 107.36 ? 218 SER R O 1 +ATOM 33935 C CB . SER R 1 218 ? 40.034 40.963 5.221 1.00 92.51 ? 218 SER R CB 1 +ATOM 33936 O OG . SER R 1 218 ? 40.640 41.287 3.976 1.00 125.57 ? 218 SER R OG 1 +ATOM 33937 N N . ALA R 1 219 ? 41.889 38.943 6.578 1.00 107.04 ? 219 ALA R N 1 +ATOM 33938 C CA . ALA R 1 219 ? 43.238 38.436 6.741 1.00 101.24 ? 219 ALA R CA 1 +ATOM 33939 C C . ALA R 1 219 ? 43.245 36.886 6.686 1.00 139.09 ? 219 ALA R C 1 +ATOM 33940 O O . ALA R 1 219 ? 44.207 36.256 6.216 1.00 106.76 ? 219 ALA R O 1 +ATOM 33941 C CB . ALA R 1 219 ? 43.821 38.960 8.046 1.00 85.56 ? 219 ALA R CB 1 +ATOM 33942 N N . ILE R 1 220 ? 42.185 36.264 7.201 1.00 172.42 ? 220 ILE R N 1 +ATOM 33943 C CA . ILE R 1 220 ? 42.106 34.796 7.217 1.00 164.79 ? 220 ILE R CA 1 +ATOM 33944 C C . ILE R 1 220 ? 41.988 34.299 5.781 1.00 129.53 ? 220 ILE R C 1 +ATOM 33945 O O . ILE R 1 220 ? 42.574 33.282 5.414 1.00 97.89 ? 220 ILE R O 1 +ATOM 33946 C CB . ILE R 1 220 ? 40.935 34.289 8.111 1.00 154.12 ? 220 ILE R CB 1 +ATOM 33947 C CG1 . ILE R 1 220 ? 41.269 34.540 9.585 1.00 165.41 ? 220 ILE R CG1 1 +ATOM 33948 C CG2 . ILE R 1 220 ? 40.665 32.803 7.874 1.00 121.51 ? 220 ILE R CG2 1 +ATOM 33949 C CD1 . ILE R 1 220 ? 40.084 34.461 10.514 1.00 166.14 ? 220 ILE R CD1 1 +ATOM 33950 N N . GLU R 1 221 ? 41.185 34.997 4.986 1.00 111.18 ? 221 GLU R N 1 +ATOM 33951 C CA . GLU R 1 221 ? 40.994 34.619 3.592 1.00 101.92 ? 221 GLU R CA 1 +ATOM 33952 C C . GLU R 1 221 ? 42.342 34.645 2.892 1.00 95.97 ? 221 GLU R C 1 +ATOM 33953 O O . GLU R 1 221 ? 42.728 33.690 2.200 1.00 85.71 ? 221 GLU R O 1 +ATOM 33954 C CB . GLU R 1 221 ? 40.007 35.589 2.926 1.00 109.79 ? 221 GLU R CB 1 +ATOM 33955 C CG . GLU R 1 221 ? 38.552 35.347 3.311 1.00 130.52 ? 221 GLU R CG 1 +ATOM 33956 C CD . GLU R 1 221 ? 37.620 36.514 3.025 1.00 134.91 ? 221 GLU R CD 1 +ATOM 33957 O OE1 . GLU R 1 221 ? 38.043 37.694 3.121 1.00 103.50 ? 221 GLU R OE1 1 +ATOM 33958 O OE2 . GLU R 1 221 ? 36.461 36.236 2.626 1.00 173.63 ? 221 GLU R OE2 1 +ATOM 33959 N N . THR R 1 222 ? 43.034 35.769 3.055 1.00 93.60 ? 222 THR R N 1 +ATOM 33960 C CA . THR R 1 222 ? 44.356 35.983 2.474 1.00 91.95 ? 222 THR R CA 1 +ATOM 33961 C C . THR R 1 222 ? 45.272 34.823 2.835 1.00 95.48 ? 222 THR R C 1 +ATOM 33962 O O . THR R 1 222 ? 45.992 34.292 1.975 1.00 73.94 ? 222 THR R O 1 +ATOM 33963 C CB . THR R 1 222 ? 44.969 37.304 3.008 1.00 99.61 ? 222 THR R CB 1 +ATOM 33964 O OG1 . THR R 1 222 ? 44.292 38.439 2.440 1.00 66.12 ? 222 THR R OG1 1 +ATOM 33965 C CG2 . THR R 1 222 ? 46.494 37.370 2.730 1.00 93.61 ? 222 THR R CG2 1 +ATOM 33966 N N . GLY R 1 223 ? 45.263 34.461 4.118 1.00 106.21 ? 223 GLY R N 1 +ATOM 33967 C CA . GLY R 1 223 ? 46.062 33.339 4.598 1.00 132.41 ? 223 GLY R CA 1 +ATOM 33968 C C . GLY R 1 223 ? 45.731 32.050 3.858 1.00 152.81 ? 223 GLY R C 1 +ATOM 33969 O O . GLY R 1 223 ? 46.623 31.240 3.565 1.00 136.72 ? 223 GLY R O 1 +ATOM 33970 N N . VAL R 1 224 ? 44.442 31.835 3.584 1.00 146.00 ? 224 VAL R N 1 +ATOM 33971 C CA . VAL R 1 224 ? 44.001 30.593 2.943 1.00 117.84 ? 224 VAL R CA 1 +ATOM 33972 C C . VAL R 1 224 ? 44.572 30.546 1.536 1.00 136.51 ? 224 VAL R C 1 +ATOM 33973 O O . VAL R 1 224 ? 45.052 29.515 1.080 1.00 128.34 ? 224 VAL R O 1 +ATOM 33974 C CB . VAL R 1 224 ? 42.471 30.490 2.881 1.00 97.89 ? 224 VAL R CB 1 +ATOM 33975 C CG1 . VAL R 1 224 ? 42.074 29.301 2.027 1.00 92.59 ? 224 VAL R CG1 1 +ATOM 33976 C CG2 . VAL R 1 224 ? 41.895 30.357 4.275 1.00 107.60 ? 224 VAL R CG2 1 +ATOM 33977 N N . ILE R 1 225 ? 44.560 31.693 0.859 1.00 150.34 ? 225 ILE R N 1 +ATOM 33978 C CA . ILE R 1 225 ? 45.133 31.776 -0.489 1.00 126.77 ? 225 ILE R CA 1 +ATOM 33979 C C . ILE R 1 225 ? 46.621 31.427 -0.470 1.00 117.75 ? 225 ILE R C 1 +ATOM 33980 O O . ILE R 1 225 ? 47.039 30.554 -1.224 1.00 79.57 ? 225 ILE R O 1 +ATOM 33981 C CB . ILE R 1 225 ? 44.931 33.164 -1.129 1.00 102.61 ? 225 ILE R CB 1 +ATOM 33982 C CG1 . ILE R 1 225 ? 43.443 33.400 -1.411 1.00 92.15 ? 225 ILE R CG1 1 +ATOM 33983 C CG2 . ILE R 1 225 ? 45.710 33.261 -2.427 1.00 86.62 ? 225 ILE R CG2 1 +ATOM 33984 C CD1 . ILE R 1 225 ? 43.090 34.856 -1.624 1.00 92.04 ? 225 ILE R CD1 1 +ATOM 33985 N N . PHE R 1 226 ? 47.393 32.087 0.409 1.00 98.67 ? 226 PHE R N 1 +ATOM 33986 C CA . PHE R 1 226 ? 48.834 31.824 0.536 1.00 84.47 ? 226 PHE R CA 1 +ATOM 33987 C C . PHE R 1 226 ? 49.102 30.352 0.842 1.00 109.36 ? 226 PHE R C 1 +ATOM 33988 O O . PHE R 1 226 ? 50.099 29.793 0.396 1.00 82.72 ? 226 PHE R O 1 +ATOM 33989 C CB . PHE R 1 226 ? 49.465 32.693 1.612 1.00 77.12 ? 226 PHE R CB 1 +ATOM 33990 C CG . PHE R 1 226 ? 49.768 34.111 1.174 1.00 91.49 ? 226 PHE R CG 1 +ATOM 33991 C CD1 . PHE R 1 226 ? 50.648 34.361 0.132 1.00 99.98 ? 226 PHE R CD1 1 +ATOM 33992 C CD2 . PHE R 1 226 ? 49.240 35.206 1.871 1.00 93.27 ? 226 PHE R CD2 1 +ATOM 33993 C CE1 . PHE R 1 226 ? 50.946 35.665 -0.257 1.00 99.32 ? 226 PHE R CE1 1 +ATOM 33994 C CE2 . PHE R 1 226 ? 49.559 36.505 1.512 1.00 92.77 ? 226 PHE R CE2 1 +ATOM 33995 C CZ . PHE R 1 226 ? 50.402 36.736 0.435 1.00 104.14 ? 226 PHE R CZ 1 +ATOM 33996 N N . LEU R 1 227 ? 48.178 29.706 1.558 1.00 154.88 ? 227 LEU R N 1 +ATOM 33997 C CA . LEU R 1 227 ? 48.300 28.259 1.849 1.00 155.98 ? 227 LEU R CA 1 +ATOM 33998 C C . LEU R 1 227 ? 48.148 27.448 0.603 1.00 138.48 ? 227 LEU R C 1 +ATOM 33999 O O . LEU R 1 227 ? 48.894 26.503 0.396 1.00 121.67 ? 227 LEU R O 1 +ATOM 34000 C CB . LEU R 1 227 ? 47.226 27.757 2.821 1.00 151.55 ? 227 LEU R CB 1 +ATOM 34001 C CG . LEU R 1 227 ? 47.672 27.224 4.180 1.00 165.56 ? 227 LEU R CG 1 +ATOM 34002 C CD1 . LEU R 1 227 ? 48.918 27.934 4.567 1.00 162.14 ? 227 LEU R CD1 1 +ATOM 34003 C CD2 . LEU R 1 227 ? 46.685 27.266 5.350 1.00 181.75 ? 227 LEU R CD2 1 +ATOM 34004 N N . ILE R 1 228 ? 47.129 27.779 -0.191 1.00 124.52 ? 228 ILE R N 1 +ATOM 34005 C CA . ILE R 1 228 ? 46.822 27.006 -1.393 1.00 119.11 ? 228 ILE R CA 1 +ATOM 34006 C C . ILE R 1 228 ? 47.962 27.154 -2.375 1.00 127.31 ? 228 ILE R C 1 +ATOM 34007 O O . ILE R 1 228 ? 48.461 26.168 -2.911 1.00 98.88 ? 228 ILE R O 1 +ATOM 34008 C CB . ILE R 1 228 ? 45.518 27.459 -2.083 1.00 106.46 ? 228 ILE R CB 1 +ATOM 34009 C CG1 . ILE R 1 228 ? 44.310 27.203 -1.181 1.00 118.10 ? 228 ILE R CG1 1 +ATOM 34010 C CG2 . ILE R 1 228 ? 45.322 26.690 -3.381 1.00 91.49 ? 228 ILE R CG2 1 +ATOM 34011 C CD1 . ILE R 1 228 ? 43.048 27.924 -1.599 1.00 98.99 ? 228 ILE R CD1 1 +ATOM 34012 N N . ASN R 1 229 ? 48.402 28.396 -2.572 1.00 146.78 ? 229 ASN R N 1 +ATOM 34013 C CA . ASN R 1 229 ? 49.503 28.689 -3.491 1.00 154.47 ? 229 ASN R CA 1 +ATOM 34014 C C . ASN R 1 229 ? 50.788 27.977 -3.060 1.00 166.60 ? 229 ASN R C 1 +ATOM 34015 O O . ASN R 1 229 ? 51.458 27.338 -3.872 1.00 148.96 ? 229 ASN R O 1 +ATOM 34016 C CB . ASN R 1 229 ? 49.734 30.202 -3.565 1.00 148.67 ? 229 ASN R CB 1 +ATOM 34017 C CG . ASN R 1 229 ? 50.539 30.618 -4.778 1.00 170.53 ? 229 ASN R CG 1 +ATOM 34018 O OD1 . ASN R 1 229 ? 50.619 29.891 -5.769 1.00 165.02 ? 229 ASN R OD1 1 +ATOM 34019 N ND2 . ASN R 1 229 ? 51.184 31.775 -4.682 1.00 194.56 ? 229 ASN R ND2 1 +ATOM 34020 N N . ASP R 1 230 ? 51.079 28.037 -1.761 1.00 183.02 ? 230 ASP R N 1 +ATOM 34021 C CA . ASP R 1 230 ? 52.227 27.356 -1.194 1.00 179.33 ? 230 ASP R CA 1 +ATOM 34022 C C . ASP R 1 230 ? 52.126 25.843 -1.440 1.00 195.54 ? 230 ASP R C 1 +ATOM 34023 O O . ASP R 1 230 ? 53.117 25.182 -1.758 1.00 181.94 ? 230 ASP R O 1 +ATOM 34024 C CB . ASP R 1 230 ? 52.330 27.659 0.304 1.00 161.29 ? 230 ASP R CB 1 +ATOM 34025 C CG . ASP R 1 230 ? 53.603 27.123 0.919 1.00 190.38 ? 230 ASP R CG 1 +ATOM 34026 O OD1 . ASP R 1 230 ? 54.681 27.678 0.595 1.00 116.44 ? 230 ASP R OD1 1 +ATOM 34027 O OD2 . ASP R 1 230 ? 53.535 26.097 1.672 1.00 271.62 ? 230 ASP R OD2 1 +ATOM 34028 N N . GLY R 1 231 ? 50.931 25.289 -1.259 1.00 189.43 ? 231 GLY R N 1 +ATOM 34029 C CA . GLY R 1 231 ? 50.726 23.857 -1.443 1.00 184.57 ? 231 GLY R CA 1 +ATOM 34030 C C . GLY R 1 231 ? 50.897 23.450 -2.895 1.00 165.01 ? 231 GLY R C 1 +ATOM 34031 O O . GLY R 1 231 ? 51.356 22.335 -3.193 1.00 106.59 ? 231 GLY R O 1 +ATOM 34032 N N . ILE R 1 232 ? 50.473 24.333 -3.799 1.00 157.95 ? 232 ILE R N 1 +ATOM 34033 C CA . ILE R 1 232 ? 50.638 24.102 -5.231 1.00 144.39 ? 232 ILE R CA 1 +ATOM 34034 C C . ILE R 1 232 ? 52.121 23.986 -5.547 1.00 132.52 ? 232 ILE R C 1 +ATOM 34035 O O . ILE R 1 232 ? 52.542 23.033 -6.212 1.00 120.46 ? 232 ILE R O 1 +ATOM 34036 C CB . ILE R 1 232 ? 49.992 25.226 -6.074 1.00 142.00 ? 232 ILE R CB 1 +ATOM 34037 C CG1 . ILE R 1 232 ? 48.462 25.091 -6.040 1.00 139.40 ? 232 ILE R CG1 1 +ATOM 34038 C CG2 . ILE R 1 232 ? 50.503 25.197 -7.517 1.00 152.89 ? 232 ILE R CG2 1 +ATOM 34039 C CD1 . ILE R 1 232 ? 47.725 26.345 -6.456 1.00 142.91 ? 232 ILE R CD1 1 +ATOM 34040 N N . ASP R 1 233 ? 52.897 24.957 -5.068 1.00 133.01 ? 233 ASP R N 1 +ATOM 34041 C CA . ASP R 1 233 ? 54.342 24.973 -5.275 1.00 139.29 ? 233 ASP R CA 1 +ATOM 34042 C C . ASP R 1 233 ? 54.966 23.690 -4.741 1.00 144.46 ? 233 ASP R C 1 +ATOM 34043 O O . ASP R 1 233 ? 55.777 23.051 -5.422 1.00 164.51 ? 233 ASP R O 1 +ATOM 34044 C CB . ASP R 1 233 ? 54.980 26.188 -4.578 1.00 139.58 ? 233 ASP R CB 1 +ATOM 34045 C CG . ASP R 1 233 ? 54.541 27.526 -5.180 1.00 137.21 ? 233 ASP R CG 1 +ATOM 34046 O OD1 . ASP R 1 233 ? 53.644 27.535 -6.048 1.00 133.21 ? 233 ASP R OD1 1 +ATOM 34047 O OD2 . ASP R 1 233 ? 55.159 28.561 -4.834 1.00 110.44 ? 233 ASP R OD2 1 +ATOM 34048 N N . ARG R 1 234 ? 54.596 23.313 -3.519 1.00 151.91 ? 234 ARG R N 1 +ATOM 34049 C CA . ARG R 1 234 ? 55.251 22.196 -2.817 1.00 157.73 ? 234 ARG R CA 1 +ATOM 34050 C C . ARG R 1 234 ? 54.697 20.814 -3.170 1.00 120.53 ? 234 ARG R C 1 +ATOM 34051 O O . ARG R 1 234 ? 55.223 19.795 -2.705 1.00 82.97 ? 234 ARG R O 1 +ATOM 34052 C CB . ARG R 1 234 ? 55.163 22.395 -1.306 1.00 162.56 ? 234 ARG R CB 1 +ATOM 34053 C CG . ARG R 1 234 ? 56.081 23.490 -0.818 1.00 153.32 ? 234 ARG R CG 1 +ATOM 34054 C CD . ARG R 1 234 ? 55.652 24.034 0.519 1.00 125.23 ? 234 ARG R CD 1 +ATOM 34055 N NE . ARG R 1 234 ? 56.546 25.120 0.898 1.00 142.35 ? 234 ARG R NE 1 +ATOM 34056 C CZ . ARG R 1 234 ? 57.263 25.154 2.021 1.00 157.63 ? 234 ARG R CZ 1 +ATOM 34057 N NH1 . ARG R 1 234 ? 57.147 24.188 2.925 1.00 121.85 ? 234 ARG R NH1 1 +ATOM 34058 N NH2 . ARG R 1 234 ? 58.079 26.186 2.247 1.00 180.90 ? 234 ARG R NH2 1 +ATOM 34059 N N . GLY R 1 235 ? 53.695 20.783 -4.046 1.00 100.51 ? 235 GLY R N 1 +ATOM 34060 C CA . GLY R 1 235 ? 53.211 19.525 -4.594 1.00 102.62 ? 235 GLY R CA 1 +ATOM 34061 C C . GLY R 1 235 ? 52.323 18.808 -3.613 1.00 104.70 ? 235 GLY R C 1 +ATOM 34062 O O . GLY R 1 235 ? 52.292 17.574 -3.586 1.00 89.33 ? 235 GLY R O 1 +ATOM 34063 N N . LEU R 1 236 ? 51.594 19.571 -2.803 1.00 125.04 ? 236 LEU R N 1 +ATOM 34064 C CA . LEU R 1 236 ? 50.525 18.979 -1.979 1.00 147.13 ? 236 LEU R CA 1 +ATOM 34065 C C . LEU R 1 236 ? 49.336 18.649 -2.873 1.00 122.22 ? 236 LEU R C 1 +ATOM 34066 O O . LEU R 1 236 ? 48.800 17.540 -2.829 1.00 93.73 ? 236 LEU R O 1 +ATOM 34067 C CB . LEU R 1 236 ? 50.076 19.912 -0.840 1.00 139.17 ? 236 LEU R CB 1 +ATOM 34068 C CG . LEU R 1 236 ? 50.896 19.914 0.461 1.00 121.81 ? 236 LEU R CG 1 +ATOM 34069 C CD1 . LEU R 1 236 ? 52.167 20.735 0.291 1.00 129.84 ? 236 LEU R CD1 1 +ATOM 34070 C CD2 . LEU R 1 236 ? 50.068 20.465 1.606 1.00 110.14 ? 236 LEU R CD2 1 +ATOM 34071 N N . TRP R 1 237 ? 48.945 19.615 -3.689 1.00 114.47 ? 237 TRP R N 1 +ATOM 34072 C CA . TRP R 1 237 ? 47.797 19.451 -4.567 1.00 152.50 ? 237 TRP R CA 1 +ATOM 34073 C C . TRP R 1 237 ? 48.090 20.065 -5.935 1.00 182.78 ? 237 TRP R C 1 +ATOM 34074 O O . TRP R 1 237 ? 49.054 20.830 -6.088 1.00 219.19 ? 237 TRP R O 1 +ATOM 34075 C CB . TRP R 1 237 ? 46.553 20.079 -3.933 1.00 140.51 ? 237 TRP R CB 1 +ATOM 34076 C CG . TRP R 1 237 ? 46.858 21.269 -3.109 1.00 142.61 ? 237 TRP R CG 1 +ATOM 34077 C CD1 . TRP R 1 237 ? 47.299 22.478 -3.556 1.00 168.92 ? 237 TRP R CD1 1 +ATOM 34078 C CD2 . TRP R 1 237 ? 46.754 21.382 -1.686 1.00 143.25 ? 237 TRP R CD2 1 +ATOM 34079 N NE1 . TRP R 1 237 ? 47.483 23.336 -2.500 1.00 161.89 ? 237 TRP R NE1 1 +ATOM 34080 C CE2 . TRP R 1 237 ? 47.138 22.692 -1.342 1.00 148.09 ? 237 TRP R CE2 1 +ATOM 34081 C CE3 . TRP R 1 237 ? 46.351 20.512 -0.672 1.00 151.40 ? 237 TRP R CE3 1 +ATOM 34082 C CZ2 . TRP R 1 237 ? 47.147 23.148 -0.029 1.00 136.67 ? 237 TRP R CZ2 1 +ATOM 34083 C CZ3 . TRP R 1 237 ? 46.362 20.972 0.638 1.00 152.21 ? 237 TRP R CZ3 1 +ATOM 34084 C CH2 . TRP R 1 237 ? 46.768 22.273 0.946 1.00 137.76 ? 237 TRP R CH2 1 +ATOM 34085 N N . ASP R 1 238 ? 47.264 19.718 -6.924 1.00 181.19 ? 238 ASP R N 1 +ATOM 34086 C CA . ASP R 1 238 ? 47.517 20.095 -8.312 1.00 151.31 ? 238 ASP R CA 1 +ATOM 34087 C C . ASP R 1 238 ? 46.317 20.761 -8.978 1.00 144.55 ? 238 ASP R C 1 +ATOM 34088 O O . ASP R 1 238 ? 45.160 20.440 -8.691 1.00 111.08 ? 238 ASP R O 1 +ATOM 34089 C CB . ASP R 1 238 ? 47.947 18.883 -9.132 1.00 120.60 ? 238 ASP R CB 1 +ATOM 34090 C CG . ASP R 1 238 ? 49.173 18.193 -8.550 1.00 125.40 ? 238 ASP R CG 1 +ATOM 34091 O OD1 . ASP R 1 238 ? 49.018 17.426 -7.592 1.00 86.84 ? 238 ASP R OD1 1 +ATOM 34092 O OD2 . ASP R 1 238 ? 50.295 18.409 -9.054 1.00 164.33 ? 238 ASP R OD2 1 +ATOM 34093 N N . LEU R 1 239 ? 46.627 21.692 -9.875 1.00 135.03 ? 239 LEU R N 1 +ATOM 34094 C CA . LEU R 1 239 ? 45.635 22.486 -10.568 1.00 130.28 ? 239 LEU R CA 1 +ATOM 34095 C C . LEU R 1 239 ? 45.015 21.641 -11.715 1.00 155.92 ? 239 LEU R C 1 +ATOM 34096 O O . LEU R 1 239 ? 45.667 20.753 -12.309 1.00 154.40 ? 239 LEU R O 1 +ATOM 34097 C CB . LEU R 1 239 ? 46.268 23.853 -10.977 1.00 118.72 ? 239 LEU R CB 1 +ATOM 34098 C CG . LEU R 1 239 ? 45.420 25.081 -10.649 1.00 123.23 ? 239 LEU R CG 1 +ATOM 34099 C CD1 . LEU R 1 239 ? 46.120 26.359 -11.068 1.00 121.68 ? 239 LEU R CD1 1 +ATOM 34100 C CD2 . LEU R 1 239 ? 44.057 25.001 -11.336 1.00 120.52 ? 239 LEU R CD2 1 +ATOM 34101 N N . GLN R 1 240 ? 43.701 21.790 -11.903 1.00 159.04 ? 240 GLN R N 1 +ATOM 34102 C CA . GLN R 1 240 ? 43.015 21.169 -13.041 1.00 151.24 ? 240 GLN R CA 1 +ATOM 34103 C C . GLN R 1 240 ? 43.743 21.523 -14.337 1.00 146.88 ? 240 GLN R C 1 +ATOM 34104 O O . GLN R 1 240 ? 44.158 20.642 -15.096 1.00 111.64 ? 240 GLN R O 1 +ATOM 34105 C CB . GLN R 1 240 ? 41.547 21.644 -13.107 1.00 143.39 ? 240 GLN R CB 1 +ATOM 34106 C CG . GLN R 1 240 ? 40.706 20.912 -14.142 1.00 128.40 ? 240 GLN R CG 1 +ATOM 34107 C CD . GLN R 1 240 ? 40.558 19.438 -13.797 1.00 137.94 ? 240 GLN R CD 1 +ATOM 34108 O OE1 . GLN R 1 240 ? 39.704 19.063 -12.984 1.00 186.19 ? 240 GLN R OE1 1 +ATOM 34109 N NE2 . GLN R 1 240 ? 41.398 18.592 -14.396 1.00 112.41 ? 240 GLN R NE2 1 +ATOM 34110 N N . ASN R 1 241 ? 43.871 22.825 -14.580 1.00 157.36 ? 241 ASN R N 1 +ATOM 34111 C CA . ASN R 1 241 ? 44.542 23.346 -15.766 1.00 151.57 ? 241 ASN R CA 1 +ATOM 34112 C C . ASN R 1 241 ? 45.923 23.862 -15.422 1.00 155.04 ? 241 ASN R C 1 +ATOM 34113 O O . ASN R 1 241 ? 46.057 24.906 -14.755 1.00 183.81 ? 241 ASN R O 1 +ATOM 34114 C CB . ASN R 1 241 ? 43.727 24.490 -16.369 1.00 147.84 ? 241 ASN R CB 1 +ATOM 34115 C CG . ASN R 1 241 ? 42.916 24.058 -17.569 1.00 166.19 ? 241 ASN R CG 1 +ATOM 34116 O OD1 . ASN R 1 241 ? 43.312 24.308 -18.706 1.00 159.64 ? 241 ASN R OD1 1 +ATOM 34117 N ND2 . ASN R 1 241 ? 41.800 23.368 -17.330 1.00 179.66 ? 241 ASN R ND2 1 +ATOM 34118 N N . LYS R 1 242 ? 46.948 23.150 -15.889 1.00 133.64 ? 242 LYS R N 1 +ATOM 34119 C CA . LYS R 1 242 ? 48.329 23.551 -15.624 1.00 141.45 ? 242 LYS R CA 1 +ATOM 34120 C C . LYS R 1 242 ? 48.625 24.886 -16.310 1.00 152.19 ? 242 LYS R C 1 +ATOM 34121 O O . LYS R 1 242 ? 49.471 25.665 -15.850 1.00 113.56 ? 242 LYS R O 1 +ATOM 34122 C CB . LYS R 1 242 ? 49.304 22.465 -16.088 1.00 123.37 ? 242 LYS R CB 1 +ATOM 34123 C CG . LYS R 1 242 ? 48.939 21.067 -15.612 1.00 122.58 ? 242 LYS R CG 1 +ATOM 34124 C CD . LYS R 1 242 ? 50.094 20.398 -14.882 1.00 131.45 ? 242 LYS R CD 1 +ATOM 34125 C CE . LYS R 1 242 ? 49.615 19.757 -13.584 1.00 157.02 ? 242 LYS R CE 1 +ATOM 34126 N NZ . LYS R 1 242 ? 50.677 18.959 -12.914 1.00 154.73 ? 242 LYS R NZ 1 +ATOM 34127 N N . ALA R 1 243 ? 47.867 25.149 -17.379 1.00 180.41 ? 243 ALA R N 1 +ATOM 34128 C CA . ALA R 1 243 ? 47.891 26.422 -18.098 1.00 185.09 ? 243 ALA R CA 1 +ATOM 34129 C C . ALA R 1 243 ? 47.455 27.587 -17.209 1.00 188.34 ? 243 ALA R C 1 +ATOM 34130 O O . ALA R 1 243 ? 47.739 28.747 -17.526 1.00 202.43 ? 243 ALA R O 1 +ATOM 34131 C CB . ALA R 1 243 ? 46.990 26.345 -19.327 1.00 171.93 ? 243 ALA R CB 1 +ATOM 34132 N N . GLU R 1 244 ? 46.753 27.285 -16.113 1.00 157.32 ? 244 GLU R N 1 +ATOM 34133 C CA . GLU R 1 244 ? 46.249 28.335 -15.235 1.00 140.85 ? 244 GLU R CA 1 +ATOM 34134 C C . GLU R 1 244 ? 47.211 28.642 -14.093 1.00 143.26 ? 244 GLU R C 1 +ATOM 34135 O O . GLU R 1 244 ? 46.852 29.373 -13.183 1.00 115.44 ? 244 GLU R O 1 +ATOM 34136 C CB . GLU R 1 244 ? 44.881 27.959 -14.669 1.00 137.00 ? 244 GLU R CB 1 +ATOM 34137 C CG . GLU R 1 244 ? 43.751 28.040 -15.675 1.00 150.13 ? 244 GLU R CG 1 +ATOM 34138 C CD . GLU R 1 244 ? 42.379 27.924 -15.030 1.00 166.65 ? 244 GLU R CD 1 +ATOM 34139 O OE1 . GLU R 1 244 ? 41.975 26.799 -14.677 1.00 160.04 ? 244 GLU R OE1 1 +ATOM 34140 O OE2 . GLU R 1 244 ? 41.697 28.965 -14.893 1.00 170.24 ? 244 GLU R OE2 1 +ATOM 34141 N N . ARG R 1 245 ? 48.442 28.155 -14.194 1.00 135.62 ? 245 ARG R N 1 +ATOM 34142 C CA . ARG R 1 245 ? 49.472 28.470 -13.211 1.00 137.02 ? 245 ARG R CA 1 +ATOM 34143 C C . ARG R 1 245 ? 49.775 29.971 -13.131 1.00 155.62 ? 245 ARG R C 1 +ATOM 34144 O O . ARG R 1 245 ? 50.103 30.482 -12.060 1.00 155.48 ? 245 ARG R O 1 +ATOM 34145 C CB . ARG R 1 245 ? 50.755 27.693 -13.513 1.00 136.60 ? 245 ARG R CB 1 +ATOM 34146 C CG . ARG R 1 245 ? 51.846 27.866 -12.468 1.00 145.67 ? 245 ARG R CG 1 +ATOM 34147 C CD . ARG R 1 245 ? 53.051 26.994 -12.779 1.00 154.52 ? 245 ARG R CD 1 +ATOM 34148 N NE . ARG R 1 245 ? 53.086 25.792 -11.952 1.00 164.84 ? 245 ARG R NE 1 +ATOM 34149 C CZ . ARG R 1 245 ? 53.261 25.796 -10.635 1.00 167.75 ? 245 ARG R CZ 1 +ATOM 34150 N NH1 . ARG R 1 245 ? 53.419 26.943 -9.988 1.00 148.70 ? 245 ARG R NH1 1 +ATOM 34151 N NH2 . ARG R 1 245 ? 53.278 24.654 -9.962 1.00 180.01 ? 245 ARG R NH2 1 +ATOM 34152 N N . GLN R 1 246 ? 49.670 30.673 -14.258 1.00 182.07 ? 246 GLN R N 1 +ATOM 34153 C CA . GLN R 1 246 ? 49.987 32.105 -14.295 1.00 172.02 ? 246 GLN R CA 1 +ATOM 34154 C C . GLN R 1 246 ? 48.737 32.955 -14.108 1.00 158.06 ? 246 GLN R C 1 +ATOM 34155 O O . GLN R 1 246 ? 48.699 34.112 -14.534 1.00 214.71 ? 246 GLN R O 1 +ATOM 34156 C CB . GLN R 1 246 ? 50.721 32.479 -15.598 1.00 162.15 ? 246 GLN R CB 1 +ATOM 34157 C CG . GLN R 1 246 ? 52.153 31.971 -15.688 1.00 143.04 ? 246 GLN R CG 1 +ATOM 34158 C CD . GLN R 1 246 ? 52.223 30.488 -15.993 1.00 166.26 ? 246 GLN R CD 1 +ATOM 34159 O OE1 . GLN R 1 246 ? 51.504 29.984 -16.864 1.00 179.30 ? 246 GLN R OE1 1 +ATOM 34160 N NE2 . GLN R 1 246 ? 53.090 29.776 -15.279 1.00 176.88 ? 246 GLN R NE2 1 +ATOM 34161 N N . ASN R 1 247 ? 47.698 32.353 -13.534 1.00 114.87 ? 247 ASN R N 1 +ATOM 34162 C CA . ASN R 1 247 ? 46.506 33.083 -13.114 1.00 137.28 ? 247 ASN R CA 1 +ATOM 34163 C C . ASN R 1 247 ? 46.883 34.407 -12.439 1.00 157.55 ? 247 ASN R C 1 +ATOM 34164 O O . ASN R 1 247 ? 47.821 34.449 -11.630 1.00 151.33 ? 247 ASN R O 1 +ATOM 34165 C CB . ASN R 1 247 ? 45.721 32.216 -12.131 1.00 140.88 ? 247 ASN R CB 1 +ATOM 34166 C CG . ASN R 1 247 ? 44.255 32.568 -12.081 1.00 128.87 ? 247 ASN R CG 1 +ATOM 34167 O OD1 . ASN R 1 247 ? 43.764 33.128 -11.087 1.00 128.54 ? 247 ASN R OD1 1 +ATOM 34168 N ND2 . ASN R 1 247 ? 43.543 32.224 -13.139 1.00 118.44 ? 247 ASN R ND2 1 +ATOM 34169 N N . ASP R 1 248 ? 46.125 35.469 -12.730 1.00 162.69 ? 248 ASP R N 1 +ATOM 34170 C CA . ASP R 1 248 ? 46.401 36.810 -12.171 1.00 198.64 ? 248 ASP R CA 1 +ATOM 34171 C C . ASP R 1 248 ? 46.532 36.789 -10.642 1.00 215.38 ? 248 ASP R C 1 +ATOM 34172 O O . ASP R 1 248 ? 47.463 37.372 -10.060 1.00 239.37 ? 248 ASP R O 1 +ATOM 34173 C CB . ASP R 1 248 ? 45.282 37.796 -12.540 1.00 177.59 ? 248 ASP R CB 1 +ATOM 34174 C CG . ASP R 1 248 ? 45.275 38.161 -14.010 1.00 158.27 ? 248 ASP R CG 1 +ATOM 34175 O OD1 . ASP R 1 248 ? 46.367 38.324 -14.601 1.00 178.77 ? 248 ASP R OD1 1 +ATOM 34176 O OD2 . ASP R 1 248 ? 44.171 38.324 -14.563 1.00 113.09 ? 248 ASP R OD2 1 +ATOM 34177 N N . ILE R 1 249 ? 45.576 36.125 -10.001 1.00 199.54 ? 249 ILE R N 1 +ATOM 34178 C CA . ILE R 1 249 ? 45.512 36.062 -8.551 1.00 175.27 ? 249 ILE R CA 1 +ATOM 34179 C C . ILE R 1 249 ? 46.708 35.276 -7.997 1.00 164.75 ? 249 ILE R C 1 +ATOM 34180 O O . ILE R 1 249 ? 47.430 35.752 -7.108 1.00 196.03 ? 249 ILE R O 1 +ATOM 34181 C CB . ILE R 1 249 ? 44.191 35.407 -8.099 1.00 152.37 ? 249 ILE R CB 1 +ATOM 34182 C CG1 . ILE R 1 249 ? 42.992 36.255 -8.549 1.00 145.90 ? 249 ILE R CG1 1 +ATOM 34183 C CG2 . ILE R 1 249 ? 44.168 35.263 -6.591 1.00 166.83 ? 249 ILE R CG2 1 +ATOM 34184 C CD1 . ILE R 1 249 ? 41.680 35.501 -8.594 1.00 129.17 ? 249 ILE R CD1 1 +ATOM 34185 N N . LEU R 1 250 ? 46.934 34.091 -8.554 1.00 137.04 ? 250 LEU R N 1 +ATOM 34186 C CA . LEU R 1 250 ? 48.034 33.231 -8.113 1.00 152.50 ? 250 LEU R CA 1 +ATOM 34187 C C . LEU R 1 250 ? 49.416 33.883 -8.237 1.00 168.78 ? 250 LEU R C 1 +ATOM 34188 O O . LEU R 1 250 ? 50.268 33.701 -7.363 1.00 198.70 ? 250 LEU R O 1 +ATOM 34189 C CB . LEU R 1 250 ? 48.027 31.916 -8.887 1.00 167.37 ? 250 LEU R CB 1 +ATOM 34190 C CG . LEU R 1 250 ? 46.996 30.890 -8.408 1.00 176.07 ? 250 LEU R CG 1 +ATOM 34191 C CD1 . LEU R 1 250 ? 46.850 29.744 -9.399 1.00 206.48 ? 250 LEU R CD1 1 +ATOM 34192 C CD2 . LEU R 1 250 ? 47.387 30.353 -7.046 1.00 176.74 ? 250 LEU R CD2 1 +ATOM 34193 N N . VAL R 1 251 ? 49.635 34.635 -9.316 1.00 178.95 ? 251 VAL R N 1 +ATOM 34194 C CA . VAL R 1 251 ? 50.909 35.341 -9.505 1.00 167.78 ? 251 VAL R CA 1 +ATOM 34195 C C . VAL R 1 251 ? 51.005 36.590 -8.620 1.00 176.18 ? 251 VAL R C 1 +ATOM 34196 O O . VAL R 1 251 ? 52.105 37.039 -8.285 1.00 166.99 ? 251 VAL R O 1 +ATOM 34197 C CB . VAL R 1 251 ? 51.149 35.736 -10.977 1.00 155.42 ? 251 VAL R CB 1 +ATOM 34198 C CG1 . VAL R 1 251 ? 51.049 34.512 -11.875 1.00 141.95 ? 251 VAL R CG1 1 +ATOM 34199 C CG2 . VAL R 1 251 ? 50.186 36.834 -11.426 1.00 158.70 ? 251 VAL R CG2 1 +ATOM 34200 N N . LYS R 1 252 ? 49.854 37.149 -8.248 1.00 157.89 ? 252 LYS R N 1 +ATOM 34201 C CA . LYS R 1 252 ? 49.811 38.282 -7.325 1.00 128.24 ? 252 LYS R CA 1 +ATOM 34202 C C . LYS R 1 252 ? 50.289 37.858 -5.922 1.00 146.83 ? 252 LYS R C 1 +ATOM 34203 O O . LYS R 1 252 ? 51.148 38.514 -5.317 1.00 140.36 ? 252 LYS R O 1 +ATOM 34204 C CB . LYS R 1 252 ? 48.393 38.838 -7.282 1.00 114.12 ? 252 LYS R CB 1 +ATOM 34205 C CG . LYS R 1 252 ? 48.185 40.004 -6.339 1.00 123.56 ? 252 LYS R CG 1 +ATOM 34206 C CD . LYS R 1 252 ? 46.723 40.447 -6.365 1.00 131.88 ? 252 LYS R CD 1 +ATOM 34207 C CE . LYS R 1 252 ? 46.163 40.640 -4.963 1.00 129.24 ? 252 LYS R CE 1 +ATOM 34208 N NZ . LYS R 1 252 ? 44.688 40.824 -4.956 1.00 124.29 ? 252 LYS R NZ 1 +ATOM 34209 N N . TYR R 1 253 ? 49.789 36.716 -5.444 1.00 160.00 ? 253 TYR R N 1 +ATOM 34210 C CA . TYR R 1 253 ? 50.162 36.184 -4.116 1.00 134.98 ? 253 TYR R CA 1 +ATOM 34211 C C . TYR R 1 253 ? 51.533 35.521 -4.139 1.00 135.92 ? 253 TYR R C 1 +ATOM 34212 O O . TYR R 1 253 ? 52.273 35.575 -3.155 1.00 139.75 ? 253 TYR R O 1 +ATOM 34213 C CB . TYR R 1 253 ? 49.101 35.203 -3.597 1.00 108.39 ? 253 TYR R CB 1 +ATOM 34214 C CG . TYR R 1 253 ? 47.823 35.914 -3.189 1.00 123.77 ? 253 TYR R CG 1 +ATOM 34215 C CD1 . TYR R 1 253 ? 47.697 36.513 -1.934 1.00 107.28 ? 253 TYR R CD1 1 +ATOM 34216 C CD2 . TYR R 1 253 ? 46.789 36.112 -4.108 1.00 139.78 ? 253 TYR R CD2 1 +ATOM 34217 C CE1 . TYR R 1 253 ? 46.564 37.244 -1.605 1.00 91.81 ? 253 TYR R CE1 1 +ATOM 34218 C CE2 . TYR R 1 253 ? 45.647 36.841 -3.775 1.00 111.50 ? 253 TYR R CE2 1 +ATOM 34219 C CZ . TYR R 1 253 ? 45.536 37.387 -2.512 1.00 88.49 ? 253 TYR R CZ 1 +ATOM 34220 O OH . TYR R 1 253 ? 44.366 38.022 -2.144 1.00 81.10 ? 253 TYR R OH 1 +ATOM 34221 N N . ARG R 1 254 ? 51.882 34.934 -5.282 1.00 146.68 ? 254 ARG R N 1 +ATOM 34222 C CA . ARG R 1 254 ? 53.249 34.466 -5.528 1.00 132.85 ? 254 ARG R CA 1 +ATOM 34223 C C . ARG R 1 254 ? 54.245 35.619 -5.404 1.00 139.01 ? 254 ARG R C 1 +ATOM 34224 O O . ARG R 1 254 ? 55.327 35.462 -4.835 1.00 105.77 ? 254 ARG R O 1 +ATOM 34225 C CB . ARG R 1 254 ? 53.364 33.852 -6.926 1.00 140.32 ? 254 ARG R CB 1 +ATOM 34226 C CG . ARG R 1 254 ? 54.722 33.232 -7.191 1.00 150.18 ? 254 ARG R CG 1 +ATOM 34227 C CD . ARG R 1 254 ? 54.706 32.279 -8.373 1.00 180.06 ? 254 ARG R CD 1 +ATOM 34228 N NE . ARG R 1 254 ? 53.889 31.089 -8.148 1.00 179.60 ? 254 ARG R NE 1 +ATOM 34229 C CZ . ARG R 1 254 ? 52.720 30.840 -8.732 1.00 178.75 ? 254 ARG R CZ 1 +ATOM 34230 N NH1 . ARG R 1 254 ? 52.174 31.712 -9.573 1.00 159.26 ? 254 ARG R NH1 1 +ATOM 34231 N NH2 . ARG R 1 254 ? 52.081 29.708 -8.461 1.00 169.58 ? 254 ARG R NH2 1 +ATOM 34232 N N . HIS R 1 255 ? 53.852 36.788 -5.922 1.00 170.08 ? 255 HIS R N 1 +ATOM 34233 C CA . HIS R 1 255 ? 54.690 37.992 -5.870 1.00 169.61 ? 255 HIS R CA 1 +ATOM 34234 C C . HIS R 1 255 ? 54.862 38.533 -4.454 1.00 144.27 ? 255 HIS R C 1 +ATOM 34235 O O . HIS R 1 255 ? 55.922 39.049 -4.105 1.00 115.56 ? 255 HIS R O 1 +ATOM 34236 C CB . HIS R 1 255 ? 54.130 39.095 -6.792 1.00 173.27 ? 255 HIS R CB 1 +ATOM 34237 C CG . HIS R 1 255 ? 54.916 39.293 -8.049 1.00 173.94 ? 255 HIS R CG 1 +ATOM 34238 N ND1 . HIS R 1 255 ? 54.848 38.420 -9.112 1.00 189.56 ? 255 HIS R ND1 1 +ATOM 34239 C CD2 . HIS R 1 255 ? 55.780 40.270 -8.415 1.00 165.01 ? 255 HIS R CD2 1 +ATOM 34240 C CE1 . HIS R 1 255 ? 55.647 38.844 -10.075 1.00 201.52 ? 255 HIS R CE1 1 +ATOM 34241 N NE2 . HIS R 1 255 ? 56.225 39.964 -9.677 1.00 189.00 ? 255 HIS R NE2 1 +ATOM 34242 N N . MET R 1 256 ? 53.818 38.431 -3.639 1.00 142.64 ? 256 MET R N 1 +ATOM 34243 C CA . MET R 1 256 ? 53.911 38.917 -2.264 1.00 128.15 ? 256 MET R CA 1 +ATOM 34244 C C . MET R 1 256 ? 54.920 38.088 -1.442 1.00 128.11 ? 256 MET R C 1 +ATOM 34245 O O . MET R 1 256 ? 55.446 38.586 -0.435 1.00 89.48 ? 256 MET R O 1 +ATOM 34246 C CB . MET R 1 256 ? 52.512 38.968 -1.624 1.00 133.96 ? 256 MET R CB 1 +ATOM 34247 C CG . MET R 1 256 ? 51.493 39.758 -2.449 1.00 134.68 ? 256 MET R CG 1 +ATOM 34248 S SD . MET R 1 256 ? 50.031 40.324 -1.568 1.00 175.93 ? 256 MET R SD 1 +ATOM 34249 C CE . MET R 1 256 ? 50.750 41.566 -0.482 1.00 159.43 ? 256 MET R CE 1 +ATOM 34250 N N . SER R 1 257 ? 55.173 36.842 -1.881 1.00 140.33 ? 257 SER R N 1 +ATOM 34251 C CA . SER R 1 257 ? 56.159 35.934 -1.244 1.00 119.40 ? 257 SER R CA 1 +ATOM 34252 C C . SER R 1 257 ? 57.591 36.243 -1.640 1.00 103.69 ? 257 SER R C 1 +ATOM 34253 O O . SER R 1 257 ? 58.184 37.158 -1.071 1.00 120.17 ? 257 SER R O 1 +ATOM 34254 C CB . SER R 1 257 ? 55.860 34.477 -1.594 1.00 98.77 ? 257 SER R CB 1 +ATOM 34255 O OG . SER R 1 257 ? 54.459 34.202 -1.512 1.00 127.64 ? 257 SER R OG 1 +# +loop_ +_pdbx_poly_seq_scheme.asym_id +_pdbx_poly_seq_scheme.entity_id +_pdbx_poly_seq_scheme.seq_id +_pdbx_poly_seq_scheme.mon_id +_pdbx_poly_seq_scheme.ndb_seq_num +_pdbx_poly_seq_scheme.pdb_seq_num +_pdbx_poly_seq_scheme.auth_seq_num +_pdbx_poly_seq_scheme.pdb_mon_id +_pdbx_poly_seq_scheme.auth_mon_id +_pdbx_poly_seq_scheme.pdb_strand_id +_pdbx_poly_seq_scheme.pdb_ins_code +_pdbx_poly_seq_scheme.hetero +A 1 1 CYS 1 1 ? ? ? A . n +A 1 2 LEU 2 2 2 LEU LEU A . n +A 1 3 THR 3 3 3 THR THR A . n +A 1 4 ALA 4 4 4 ALA ALA A . n +A 1 5 PRO 5 5 5 PRO PRO A . n +A 1 6 PRO 6 6 6 PRO PRO A . n +A 1 7 LYS 7 7 7 LYS LYS A . n +A 1 8 GLU 8 8 8 GLU GLU A . n +A 1 9 ALA 9 9 9 ALA ALA A . n +A 1 10 ALA 10 10 10 ALA ALA A . n +A 1 11 ARG 11 11 11 ARG ARG A . n +A 1 12 PRO 12 12 12 PRO PRO A . n +A 1 13 THR 13 13 13 THR THR A . n +A 1 14 LEU 14 14 14 LEU LEU A . n +A 1 15 MET 15 15 15 MET MET A . n +A 1 16 PRO 16 16 16 PRO PRO A . n +A 1 17 ARG 17 17 17 ARG ARG A . n +A 1 18 ALA 18 18 18 ALA ALA A . n +A 1 19 GLN 19 19 19 GLN GLN A . n +A 1 20 SER 20 20 20 SER SER A . n +A 1 21 TYR 21 21 21 TYR TYR A . n +A 1 22 LYS 22 22 22 LYS LYS A . n +A 1 23 ASP 23 23 23 ASP ASP A . n +A 1 24 LEU 24 24 24 LEU LEU A . n +A 1 25 THR 25 25 25 THR THR A . n +A 1 26 HIS 26 26 26 HIS HIS A . n +A 1 27 LEU 27 27 27 LEU LEU A . n +A 1 28 PRO 28 28 28 PRO PRO A . n +A 1 29 ALA 29 29 29 ALA ALA A . n +A 1 30 PRO 30 30 30 PRO PRO A . n +A 1 31 THR 31 31 31 THR THR A . n +A 1 32 GLY 32 32 32 GLY GLY A . n +A 1 33 LYS 33 33 33 LYS LYS A . n +A 1 34 ILE 34 34 34 ILE ILE A . n +A 1 35 PHE 35 35 35 PHE PHE A . n +A 1 36 VAL 36 36 36 VAL VAL A . n +A 1 37 SER 37 37 37 SER SER A . n +A 1 38 VAL 38 38 38 VAL VAL A . n +A 1 39 TYR 39 39 39 TYR TYR A . n +A 1 40 ASN 40 40 40 ASN ASN A . n +A 1 41 ILE 41 41 41 ILE ILE A . n +A 1 42 GLN 42 42 42 GLN GLN A . n +A 1 43 ASP 43 43 43 ASP ASP A . n +A 1 44 GLU 44 44 44 GLU GLU A . n +A 1 45 THR 45 45 45 THR THR A . n +A 1 46 GLY 46 46 46 GLY GLY A . n +A 1 47 GLN 47 47 47 GLN GLN A . n +A 1 48 PHE 48 48 48 PHE PHE A . n +A 1 49 LYS 49 49 49 LYS LYS A . n +A 1 50 PRO 50 50 50 PRO PRO A . n +A 1 51 TYR 51 51 51 TYR TYR A . n +A 1 52 PRO 52 52 52 PRO PRO A . n +A 1 53 ALA 53 53 53 ALA ALA A . n +A 1 54 SER 54 54 54 SER SER A . n +A 1 55 ASN 55 55 55 ASN ASN A . n +A 1 56 PHE 56 56 56 PHE PHE A . n +A 1 57 SER 57 57 57 SER SER A . n +A 1 58 THR 58 58 58 THR THR A . n +A 1 59 ALA 59 59 59 ALA ALA A . n +A 1 60 VAL 60 60 60 VAL VAL A . n +A 1 61 PRO 61 61 61 PRO PRO A . n +A 1 62 GLN 62 62 62 GLN GLN A . n +A 1 63 SER 63 63 63 SER SER A . n +A 1 64 ALA 64 64 64 ALA ALA A . n +A 1 65 THR 65 65 65 THR THR A . n +A 1 66 ALA 66 66 66 ALA ALA A . n +A 1 67 MET 67 67 67 MET MET A . n +A 1 68 LEU 68 68 68 LEU LEU A . n +A 1 69 VAL 69 69 69 VAL VAL A . n +A 1 70 THR 70 70 70 THR THR A . n +A 1 71 ALA 71 71 71 ALA ALA A . n +A 1 72 LEU 72 72 72 LEU LEU A . n +A 1 73 LYS 73 73 73 LYS LYS A . n +A 1 74 ASP 74 74 74 ASP ASP A . n +A 1 75 SER 75 75 75 SER SER A . n +A 1 76 ARG 76 76 76 ARG ARG A . n +A 1 77 TRP 77 77 77 TRP TRP A . n +A 1 78 PHE 78 78 78 PHE PHE A . n +A 1 79 ILE 79 79 79 ILE ILE A . n +A 1 80 PRO 80 80 80 PRO PRO A . n +A 1 81 LEU 81 81 81 LEU LEU A . n +A 1 82 GLU 82 82 82 GLU GLU A . n +A 1 83 ARG 83 83 83 ARG ARG A . n +A 1 84 GLN 84 84 84 GLN GLN A . n +A 1 85 GLY 85 85 85 GLY GLY A . n +A 1 86 LEU 86 86 86 LEU LEU A . n +A 1 87 GLN 87 87 87 GLN GLN A . n +A 1 88 ASN 88 88 88 ASN ASN A . n +A 1 89 LEU 89 89 89 LEU LEU A . n +A 1 90 LEU 90 90 90 LEU LEU A . n +A 1 91 ASN 91 91 91 ASN ASN A . n +A 1 92 GLU 92 92 92 GLU GLU A . n +A 1 93 ARG 93 93 93 ARG ARG A . n +A 1 94 LYS 94 94 94 LYS LYS A . n +A 1 95 ILE 95 95 95 ILE ILE A . n +A 1 96 ILE 96 96 96 ILE ILE A . n +A 1 97 ARG 97 97 97 ARG ARG A . n +A 1 98 ALA 98 98 98 ALA ALA A . n +A 1 99 ALA 99 99 99 ALA ALA A . n +A 1 100 GLN 100 100 100 GLN GLN A . n +A 1 101 GLU 101 101 101 GLU GLU A . n +A 1 102 ASN 102 102 102 ASN ASN A . n +A 1 103 GLY 103 103 103 GLY GLY A . n +A 1 104 THR 104 104 104 THR THR A . n +A 1 105 VAL 105 105 105 VAL VAL A . n +A 1 106 ALA 106 106 106 ALA ALA A . n +A 1 107 ILE 107 107 107 ILE ILE A . n +A 1 108 ASN 108 108 108 ASN ASN A . n +A 1 109 ASN 109 109 109 ASN ASN A . n +A 1 110 ARG 110 110 110 ARG ARG A . n +A 1 111 ILE 111 111 111 ILE ILE A . n +A 1 112 PRO 112 112 112 PRO PRO A . n +A 1 113 LEU 113 113 113 LEU LEU A . n +A 1 114 GLN 114 114 114 GLN GLN A . n +A 1 115 SER 115 115 115 SER SER A . n +A 1 116 LEU 116 116 116 LEU LEU A . n +A 1 117 THR 117 117 117 THR THR A . n +A 1 118 ALA 118 118 118 ALA ALA A . n +A 1 119 ALA 119 119 119 ALA ALA A . n +A 1 120 ASN 120 120 120 ASN ASN A . n +A 1 121 ILE 121 121 121 ILE ILE A . n +A 1 122 MET 122 122 122 MET MET A . n +A 1 123 VAL 123 123 123 VAL VAL A . n +A 1 124 GLU 124 124 124 GLU GLU A . n +A 1 125 GLY 125 125 125 GLY GLY A . n +A 1 126 SER 126 126 126 SER SER A . n +A 1 127 ILE 127 127 127 ILE ILE A . n +A 1 128 ILE 128 128 128 ILE ILE A . n +A 1 129 GLY 129 129 129 GLY GLY A . n +A 1 130 TYR 130 130 130 TYR TYR A . n +A 1 131 GLU 131 131 131 GLU GLU A . n +A 1 132 SER 132 132 132 SER SER A . n +A 1 133 ASN 133 133 133 ASN ASN A . n +A 1 134 VAL 134 134 134 VAL VAL A . n +A 1 135 LYS 135 135 135 LYS LYS A . n +A 1 136 SER 136 136 136 SER SER A . n +A 1 137 GLY 137 137 137 GLY GLY A . n +A 1 138 GLY 138 138 138 GLY GLY A . n +A 1 139 VAL 139 139 139 VAL VAL A . n +A 1 140 GLY 140 140 140 GLY GLY A . n +A 1 141 ALA 141 141 141 ALA ALA A . n +A 1 142 ARG 142 142 142 ARG ARG A . n +A 1 143 TYR 143 143 143 TYR TYR A . n +A 1 144 PHE 144 144 ? ? ? A . n +A 1 145 GLY 145 145 145 GLY GLY A . n +A 1 146 ILE 146 146 146 ILE ILE A . n +A 1 147 GLY 147 147 147 GLY GLY A . n +A 1 148 ALA 148 148 148 ALA ALA A . n +A 1 149 ASP 149 149 149 ASP ASP A . n +A 1 150 THR 150 150 150 THR THR A . n +A 1 151 GLN 151 151 151 GLN GLN A . n +A 1 152 TYR 152 152 152 TYR TYR A . n +A 1 153 GLN 153 153 153 GLN GLN A . n +A 1 154 LEU 154 154 154 LEU LEU A . n +A 1 155 ASP 155 155 155 ASP ASP A . n +A 1 156 GLN 156 156 156 GLN GLN A . n +A 1 157 ILE 157 157 157 ILE ILE A . n +A 1 158 ALA 158 158 158 ALA ALA A . n +A 1 159 VAL 159 159 159 VAL VAL A . n +A 1 160 ASN 160 160 160 ASN ASN A . n +A 1 161 LEU 161 161 161 LEU LEU A . n +A 1 162 ARG 162 162 162 ARG ARG A . n +A 1 163 VAL 163 163 163 VAL VAL A . n +A 1 164 VAL 164 164 164 VAL VAL A . n +A 1 165 ASN 165 165 165 ASN ASN A . n +A 1 166 VAL 166 166 166 VAL VAL A . n +A 1 167 SER 167 167 167 SER SER A . n +A 1 168 THR 168 168 168 THR THR A . n +A 1 169 GLY 169 169 169 GLY GLY A . n +A 1 170 GLU 170 170 170 GLU GLU A . n +A 1 171 ILE 171 171 171 ILE ILE A . n +A 1 172 LEU 172 172 172 LEU LEU A . n +A 1 173 SER 173 173 173 SER SER A . n +A 1 174 SER 174 174 174 SER SER A . n +A 1 175 VAL 175 175 175 VAL VAL A . n +A 1 176 ASN 176 176 176 ASN ASN A . n +A 1 177 THR 177 177 177 THR THR A . n +A 1 178 SER 178 178 178 SER SER A . n +A 1 179 LYS 179 179 179 LYS LYS A . n +A 1 180 THR 180 180 180 THR THR A . n +A 1 181 ILE 181 181 181 ILE ILE A . n +A 1 182 LEU 182 182 182 LEU LEU A . n +A 1 183 SER 183 183 183 SER SER A . n +A 1 184 TYR 184 184 184 TYR TYR A . n +A 1 185 GLU 185 185 185 GLU GLU A . n +A 1 186 VAL 186 186 186 VAL VAL A . n +A 1 187 GLN 187 187 187 GLN GLN A . n +A 1 188 ALA 188 188 188 ALA ALA A . n +A 1 189 GLY 189 189 189 GLY GLY A . n +A 1 190 VAL 190 190 190 VAL VAL A . n +A 1 191 PHE 191 191 191 PHE PHE A . n +A 1 192 ARG 192 192 192 ARG ARG A . n +A 1 193 PHE 193 193 ? ? ? A . n +A 1 194 ILE 194 194 ? ? ? A . n +A 1 195 ASP 195 195 ? ? ? A . n +A 1 196 TYR 196 196 ? ? ? A . n +A 1 197 GLN 197 197 ? ? ? A . n +A 1 198 ARG 198 198 ? ? ? A . n +A 1 199 LEU 199 199 ? ? ? A . n +A 1 200 LEU 200 200 200 LEU LEU A . n +A 1 201 GLU 201 201 201 GLU GLU A . n +A 1 202 GLY 202 202 202 GLY GLY A . n +A 1 203 GLU 203 203 203 GLU GLU A . n +A 1 204 VAL 204 204 204 VAL VAL A . n +A 1 205 GLY 205 205 205 GLY GLY A . n +A 1 206 TYR 206 206 206 TYR TYR A . n +A 1 207 THR 207 207 207 THR THR A . n +A 1 208 SER 208 208 208 SER SER A . n +A 1 209 ASN 209 209 209 ASN ASN A . n +A 1 210 GLU 210 210 210 GLU GLU A . n +A 1 211 PRO 211 211 211 PRO PRO A . n +A 1 212 VAL 212 212 212 VAL VAL A . n +A 1 213 MET 213 213 213 MET MET A . n +A 1 214 LEU 214 214 214 LEU LEU A . n +A 1 215 CYS 215 215 215 CYS CYS A . n +A 1 216 LEU 216 216 216 LEU LEU A . n +A 1 217 MET 217 217 217 MET MET A . n +A 1 218 SER 218 218 218 SER SER A . n +A 1 219 ALA 219 219 219 ALA ALA A . n +A 1 220 ILE 220 220 220 ILE ILE A . n +A 1 221 GLU 221 221 221 GLU GLU A . n +A 1 222 THR 222 222 222 THR THR A . n +A 1 223 GLY 223 223 223 GLY GLY A . n +A 1 224 VAL 224 224 224 VAL VAL A . n +A 1 225 ILE 225 225 225 ILE ILE A . n +A 1 226 PHE 226 226 226 PHE PHE A . n +A 1 227 LEU 227 227 227 LEU LEU A . n +A 1 228 ILE 228 228 228 ILE ILE A . n +A 1 229 ASN 229 229 229 ASN ASN A . n +A 1 230 ASP 230 230 230 ASP ASP A . n +A 1 231 GLY 231 231 231 GLY GLY A . n +A 1 232 ILE 232 232 232 ILE ILE A . n +A 1 233 ASP 233 233 233 ASP ASP A . n +A 1 234 ARG 234 234 234 ARG ARG A . n +A 1 235 GLY 235 235 235 GLY GLY A . n +A 1 236 LEU 236 236 236 LEU LEU A . n +A 1 237 TRP 237 237 237 TRP TRP A . n +A 1 238 ASP 238 238 238 ASP ASP A . n +A 1 239 LEU 239 239 239 LEU LEU A . n +A 1 240 GLN 240 240 240 GLN GLN A . n +A 1 241 ASN 241 241 241 ASN ASN A . n +A 1 242 LYS 242 242 242 LYS LYS A . n +A 1 243 ALA 243 243 243 ALA ALA A . n +A 1 244 GLU 244 244 244 GLU GLU A . n +A 1 245 ARG 245 245 245 ARG ARG A . n +A 1 246 GLN 246 246 246 GLN GLN A . n +A 1 247 ASN 247 247 247 ASN ASN A . n +A 1 248 ASP 248 248 248 ASP ASP A . n +A 1 249 ILE 249 249 249 ILE ILE A . n +A 1 250 LEU 250 250 250 LEU LEU A . n +A 1 251 VAL 251 251 251 VAL VAL A . n +A 1 252 LYS 252 252 252 LYS LYS A . n +A 1 253 TYR 253 253 253 TYR TYR A . n +A 1 254 ARG 254 254 254 ARG ARG A . n +A 1 255 HIS 255 255 255 HIS HIS A . n +A 1 256 MET 256 256 256 MET MET A . n +A 1 257 SER 257 257 257 SER SER A . n +A 1 258 VAL 258 258 ? ? ? A . n +A 1 259 PRO 259 259 ? ? ? A . n +A 1 260 PRO 260 260 ? ? ? A . n +A 1 261 GLU 261 261 ? ? ? A . n +A 1 262 SER 262 262 ? ? ? A . n +B 1 1 CYS 1 1 ? ? ? B . n +B 1 2 LEU 2 2 2 LEU LEU B . n +B 1 3 THR 3 3 3 THR THR B . n +B 1 4 ALA 4 4 4 ALA ALA B . n +B 1 5 PRO 5 5 5 PRO PRO B . n +B 1 6 PRO 6 6 6 PRO PRO B . n +B 1 7 LYS 7 7 7 LYS LYS B . n +B 1 8 GLU 8 8 8 GLU GLU B . n +B 1 9 ALA 9 9 9 ALA ALA B . n +B 1 10 ALA 10 10 10 ALA ALA B . n +B 1 11 ARG 11 11 11 ARG ARG B . n +B 1 12 PRO 12 12 12 PRO PRO B . n +B 1 13 THR 13 13 13 THR THR B . n +B 1 14 LEU 14 14 14 LEU LEU B . n +B 1 15 MET 15 15 15 MET MET B . n +B 1 16 PRO 16 16 16 PRO PRO B . n +B 1 17 ARG 17 17 17 ARG ARG B . n +B 1 18 ALA 18 18 18 ALA ALA B . n +B 1 19 GLN 19 19 19 GLN GLN B . n +B 1 20 SER 20 20 20 SER SER B . n +B 1 21 TYR 21 21 21 TYR TYR B . n +B 1 22 LYS 22 22 22 LYS LYS B . n +B 1 23 ASP 23 23 23 ASP ASP B . n +B 1 24 LEU 24 24 24 LEU LEU B . n +B 1 25 THR 25 25 25 THR THR B . n +B 1 26 HIS 26 26 26 HIS HIS B . n +B 1 27 LEU 27 27 27 LEU LEU B . n +B 1 28 PRO 28 28 28 PRO PRO B . n +B 1 29 ALA 29 29 29 ALA ALA B . n +B 1 30 PRO 30 30 30 PRO PRO B . n +B 1 31 THR 31 31 31 THR THR B . n +B 1 32 GLY 32 32 32 GLY GLY B . n +B 1 33 LYS 33 33 33 LYS LYS B . n +B 1 34 ILE 34 34 34 ILE ILE B . n +B 1 35 PHE 35 35 35 PHE PHE B . n +B 1 36 VAL 36 36 36 VAL VAL B . n +B 1 37 SER 37 37 37 SER SER B . n +B 1 38 VAL 38 38 38 VAL VAL B . n +B 1 39 TYR 39 39 39 TYR TYR B . n +B 1 40 ASN 40 40 40 ASN ASN B . n +B 1 41 ILE 41 41 41 ILE ILE B . n +B 1 42 GLN 42 42 42 GLN GLN B . n +B 1 43 ASP 43 43 43 ASP ASP B . n +B 1 44 GLU 44 44 44 GLU GLU B . n +B 1 45 THR 45 45 45 THR THR B . n +B 1 46 GLY 46 46 46 GLY GLY B . n +B 1 47 GLN 47 47 47 GLN GLN B . n +B 1 48 PHE 48 48 48 PHE PHE B . n +B 1 49 LYS 49 49 49 LYS LYS B . n +B 1 50 PRO 50 50 50 PRO PRO B . n +B 1 51 TYR 51 51 51 TYR TYR B . n +B 1 52 PRO 52 52 52 PRO PRO B . n +B 1 53 ALA 53 53 53 ALA ALA B . n +B 1 54 SER 54 54 54 SER SER B . n +B 1 55 ASN 55 55 55 ASN ASN B . n +B 1 56 PHE 56 56 56 PHE PHE B . n +B 1 57 SER 57 57 57 SER SER B . n +B 1 58 THR 58 58 58 THR THR B . n +B 1 59 ALA 59 59 59 ALA ALA B . n +B 1 60 VAL 60 60 60 VAL VAL B . n +B 1 61 PRO 61 61 61 PRO PRO B . n +B 1 62 GLN 62 62 62 GLN GLN B . n +B 1 63 SER 63 63 63 SER SER B . n +B 1 64 ALA 64 64 64 ALA ALA B . n +B 1 65 THR 65 65 65 THR THR B . n +B 1 66 ALA 66 66 66 ALA ALA B . n +B 1 67 MET 67 67 67 MET MET B . n +B 1 68 LEU 68 68 68 LEU LEU B . n +B 1 69 VAL 69 69 69 VAL VAL B . n +B 1 70 THR 70 70 70 THR THR B . n +B 1 71 ALA 71 71 71 ALA ALA B . n +B 1 72 LEU 72 72 72 LEU LEU B . n +B 1 73 LYS 73 73 73 LYS LYS B . n +B 1 74 ASP 74 74 74 ASP ASP B . n +B 1 75 SER 75 75 75 SER SER B . n +B 1 76 ARG 76 76 76 ARG ARG B . n +B 1 77 TRP 77 77 77 TRP TRP B . n +B 1 78 PHE 78 78 78 PHE PHE B . n +B 1 79 ILE 79 79 79 ILE ILE B . n +B 1 80 PRO 80 80 80 PRO PRO B . n +B 1 81 LEU 81 81 81 LEU LEU B . n +B 1 82 GLU 82 82 82 GLU GLU B . n +B 1 83 ARG 83 83 83 ARG ARG B . n +B 1 84 GLN 84 84 84 GLN GLN B . n +B 1 85 GLY 85 85 85 GLY GLY B . n +B 1 86 LEU 86 86 86 LEU LEU B . n +B 1 87 GLN 87 87 87 GLN GLN B . n +B 1 88 ASN 88 88 88 ASN ASN B . n +B 1 89 LEU 89 89 89 LEU LEU B . n +B 1 90 LEU 90 90 90 LEU LEU B . n +B 1 91 ASN 91 91 91 ASN ASN B . n +B 1 92 GLU 92 92 92 GLU GLU B . n +B 1 93 ARG 93 93 93 ARG ARG B . n +B 1 94 LYS 94 94 94 LYS LYS B . n +B 1 95 ILE 95 95 95 ILE ILE B . n +B 1 96 ILE 96 96 96 ILE ILE B . n +B 1 97 ARG 97 97 97 ARG ARG B . n +B 1 98 ALA 98 98 98 ALA ALA B . n +B 1 99 ALA 99 99 99 ALA ALA B . n +B 1 100 GLN 100 100 100 GLN GLN B . n +B 1 101 GLU 101 101 101 GLU GLU B . n +B 1 102 ASN 102 102 102 ASN ASN B . n +B 1 103 GLY 103 103 103 GLY GLY B . n +B 1 104 THR 104 104 104 THR THR B . n +B 1 105 VAL 105 105 105 VAL VAL B . n +B 1 106 ALA 106 106 106 ALA ALA B . n +B 1 107 ILE 107 107 107 ILE ILE B . n +B 1 108 ASN 108 108 108 ASN ASN B . n +B 1 109 ASN 109 109 109 ASN ASN B . n +B 1 110 ARG 110 110 110 ARG ARG B . n +B 1 111 ILE 111 111 111 ILE ILE B . n +B 1 112 PRO 112 112 112 PRO PRO B . n +B 1 113 LEU 113 113 113 LEU LEU B . n +B 1 114 GLN 114 114 114 GLN GLN B . n +B 1 115 SER 115 115 115 SER SER B . n +B 1 116 LEU 116 116 116 LEU LEU B . n +B 1 117 THR 117 117 117 THR THR B . n +B 1 118 ALA 118 118 118 ALA ALA B . n +B 1 119 ALA 119 119 119 ALA ALA B . n +B 1 120 ASN 120 120 120 ASN ASN B . n +B 1 121 ILE 121 121 121 ILE ILE B . n +B 1 122 MET 122 122 122 MET MET B . n +B 1 123 VAL 123 123 123 VAL VAL B . n +B 1 124 GLU 124 124 124 GLU GLU B . n +B 1 125 GLY 125 125 125 GLY GLY B . n +B 1 126 SER 126 126 126 SER SER B . n +B 1 127 ILE 127 127 127 ILE ILE B . n +B 1 128 ILE 128 128 128 ILE ILE B . n +B 1 129 GLY 129 129 129 GLY GLY B . n +B 1 130 TYR 130 130 130 TYR TYR B . n +B 1 131 GLU 131 131 131 GLU GLU B . n +B 1 132 SER 132 132 132 SER SER B . n +B 1 133 ASN 133 133 133 ASN ASN B . n +B 1 134 VAL 134 134 134 VAL VAL B . n +B 1 135 LYS 135 135 135 LYS LYS B . n +B 1 136 SER 136 136 136 SER SER B . n +B 1 137 GLY 137 137 137 GLY GLY B . n +B 1 138 GLY 138 138 138 GLY GLY B . n +B 1 139 VAL 139 139 139 VAL VAL B . n +B 1 140 GLY 140 140 140 GLY GLY B . n +B 1 141 ALA 141 141 141 ALA ALA B . n +B 1 142 ARG 142 142 142 ARG ARG B . n +B 1 143 TYR 143 143 143 TYR TYR B . n +B 1 144 PHE 144 144 ? ? ? B . n +B 1 145 GLY 145 145 145 GLY GLY B . n +B 1 146 ILE 146 146 146 ILE ILE B . n +B 1 147 GLY 147 147 147 GLY GLY B . n +B 1 148 ALA 148 148 148 ALA ALA B . n +B 1 149 ASP 149 149 149 ASP ASP B . n +B 1 150 THR 150 150 150 THR THR B . n +B 1 151 GLN 151 151 151 GLN GLN B . n +B 1 152 TYR 152 152 152 TYR TYR B . n +B 1 153 GLN 153 153 153 GLN GLN B . n +B 1 154 LEU 154 154 154 LEU LEU B . n +B 1 155 ASP 155 155 155 ASP ASP B . n +B 1 156 GLN 156 156 156 GLN GLN B . n +B 1 157 ILE 157 157 157 ILE ILE B . n +B 1 158 ALA 158 158 158 ALA ALA B . n +B 1 159 VAL 159 159 159 VAL VAL B . n +B 1 160 ASN 160 160 160 ASN ASN B . n +B 1 161 LEU 161 161 161 LEU LEU B . n +B 1 162 ARG 162 162 162 ARG ARG B . n +B 1 163 VAL 163 163 163 VAL VAL B . n +B 1 164 VAL 164 164 164 VAL VAL B . n +B 1 165 ASN 165 165 165 ASN ASN B . n +B 1 166 VAL 166 166 166 VAL VAL B . n +B 1 167 SER 167 167 167 SER SER B . n +B 1 168 THR 168 168 168 THR THR B . n +B 1 169 GLY 169 169 169 GLY GLY B . n +B 1 170 GLU 170 170 170 GLU GLU B . n +B 1 171 ILE 171 171 171 ILE ILE B . n +B 1 172 LEU 172 172 172 LEU LEU B . n +B 1 173 SER 173 173 173 SER SER B . n +B 1 174 SER 174 174 174 SER SER B . n +B 1 175 VAL 175 175 175 VAL VAL B . n +B 1 176 ASN 176 176 176 ASN ASN B . n +B 1 177 THR 177 177 177 THR THR B . n +B 1 178 SER 178 178 178 SER SER B . n +B 1 179 LYS 179 179 179 LYS LYS B . n +B 1 180 THR 180 180 180 THR THR B . n +B 1 181 ILE 181 181 181 ILE ILE B . n +B 1 182 LEU 182 182 182 LEU LEU B . n +B 1 183 SER 183 183 183 SER SER B . n +B 1 184 TYR 184 184 184 TYR TYR B . n +B 1 185 GLU 185 185 185 GLU GLU B . n +B 1 186 VAL 186 186 186 VAL VAL B . n +B 1 187 GLN 187 187 187 GLN GLN B . n +B 1 188 ALA 188 188 188 ALA ALA B . n +B 1 189 GLY 189 189 189 GLY GLY B . n +B 1 190 VAL 190 190 190 VAL VAL B . n +B 1 191 PHE 191 191 191 PHE PHE B . n +B 1 192 ARG 192 192 192 ARG ARG B . n +B 1 193 PHE 193 193 ? ? ? B . n +B 1 194 ILE 194 194 ? ? ? B . n +B 1 195 ASP 195 195 ? ? ? B . n +B 1 196 TYR 196 196 ? ? ? B . n +B 1 197 GLN 197 197 ? ? ? B . n +B 1 198 ARG 198 198 ? ? ? B . n +B 1 199 LEU 199 199 ? ? ? B . n +B 1 200 LEU 200 200 200 LEU LEU B . n +B 1 201 GLU 201 201 201 GLU GLU B . n +B 1 202 GLY 202 202 202 GLY GLY B . n +B 1 203 GLU 203 203 203 GLU GLU B . n +B 1 204 VAL 204 204 204 VAL VAL B . n +B 1 205 GLY 205 205 205 GLY GLY B . n +B 1 206 TYR 206 206 206 TYR TYR B . n +B 1 207 THR 207 207 207 THR THR B . n +B 1 208 SER 208 208 208 SER SER B . n +B 1 209 ASN 209 209 209 ASN ASN B . n +B 1 210 GLU 210 210 210 GLU GLU B . n +B 1 211 PRO 211 211 211 PRO PRO B . n +B 1 212 VAL 212 212 212 VAL VAL B . n +B 1 213 MET 213 213 213 MET MET B . n +B 1 214 LEU 214 214 214 LEU LEU B . n +B 1 215 CYS 215 215 215 CYS CYS B . n +B 1 216 LEU 216 216 216 LEU LEU B . n +B 1 217 MET 217 217 217 MET MET B . n +B 1 218 SER 218 218 218 SER SER B . n +B 1 219 ALA 219 219 219 ALA ALA B . n +B 1 220 ILE 220 220 220 ILE ILE B . n +B 1 221 GLU 221 221 221 GLU GLU B . n +B 1 222 THR 222 222 222 THR THR B . n +B 1 223 GLY 223 223 223 GLY GLY B . n +B 1 224 VAL 224 224 224 VAL VAL B . n +B 1 225 ILE 225 225 225 ILE ILE B . n +B 1 226 PHE 226 226 226 PHE PHE B . n +B 1 227 LEU 227 227 227 LEU LEU B . n +B 1 228 ILE 228 228 228 ILE ILE B . n +B 1 229 ASN 229 229 229 ASN ASN B . n +B 1 230 ASP 230 230 230 ASP ASP B . n +B 1 231 GLY 231 231 231 GLY GLY B . n +B 1 232 ILE 232 232 232 ILE ILE B . n +B 1 233 ASP 233 233 233 ASP ASP B . n +B 1 234 ARG 234 234 234 ARG ARG B . n +B 1 235 GLY 235 235 235 GLY GLY B . n +B 1 236 LEU 236 236 236 LEU LEU B . n +B 1 237 TRP 237 237 237 TRP TRP B . n +B 1 238 ASP 238 238 238 ASP ASP B . n +B 1 239 LEU 239 239 239 LEU LEU B . n +B 1 240 GLN 240 240 240 GLN GLN B . n +B 1 241 ASN 241 241 241 ASN ASN B . n +B 1 242 LYS 242 242 242 LYS LYS B . n +B 1 243 ALA 243 243 243 ALA ALA B . n +B 1 244 GLU 244 244 244 GLU GLU B . n +B 1 245 ARG 245 245 245 ARG ARG B . n +B 1 246 GLN 246 246 246 GLN GLN B . n +B 1 247 ASN 247 247 247 ASN ASN B . n +B 1 248 ASP 248 248 248 ASP ASP B . n +B 1 249 ILE 249 249 249 ILE ILE B . n +B 1 250 LEU 250 250 250 LEU LEU B . n +B 1 251 VAL 251 251 251 VAL VAL B . n +B 1 252 LYS 252 252 252 LYS LYS B . n +B 1 253 TYR 253 253 253 TYR TYR B . n +B 1 254 ARG 254 254 254 ARG ARG B . n +B 1 255 HIS 255 255 255 HIS HIS B . n +B 1 256 MET 256 256 256 MET MET B . n +B 1 257 SER 257 257 257 SER SER B . n +B 1 258 VAL 258 258 ? ? ? B . n +B 1 259 PRO 259 259 ? ? ? B . n +B 1 260 PRO 260 260 ? ? ? B . n +B 1 261 GLU 261 261 ? ? ? B . n +B 1 262 SER 262 262 ? ? ? B . n +C 1 1 CYS 1 1 ? ? ? C . n +C 1 2 LEU 2 2 2 LEU LEU C . n +C 1 3 THR 3 3 3 THR THR C . n +C 1 4 ALA 4 4 4 ALA ALA C . n +C 1 5 PRO 5 5 5 PRO PRO C . n +C 1 6 PRO 6 6 6 PRO PRO C . n +C 1 7 LYS 7 7 7 LYS LYS C . n +C 1 8 GLU 8 8 8 GLU GLU C . n +C 1 9 ALA 9 9 9 ALA ALA C . n +C 1 10 ALA 10 10 10 ALA ALA C . n +C 1 11 ARG 11 11 11 ARG ARG C . n +C 1 12 PRO 12 12 12 PRO PRO C . n +C 1 13 THR 13 13 13 THR THR C . n +C 1 14 LEU 14 14 14 LEU LEU C . n +C 1 15 MET 15 15 15 MET MET C . n +C 1 16 PRO 16 16 16 PRO PRO C . n +C 1 17 ARG 17 17 17 ARG ARG C . n +C 1 18 ALA 18 18 18 ALA ALA C . n +C 1 19 GLN 19 19 19 GLN GLN C . n +C 1 20 SER 20 20 20 SER SER C . n +C 1 21 TYR 21 21 21 TYR TYR C . n +C 1 22 LYS 22 22 22 LYS LYS C . n +C 1 23 ASP 23 23 23 ASP ASP C . n +C 1 24 LEU 24 24 24 LEU LEU C . n +C 1 25 THR 25 25 25 THR THR C . n +C 1 26 HIS 26 26 26 HIS HIS C . n +C 1 27 LEU 27 27 27 LEU LEU C . n +C 1 28 PRO 28 28 28 PRO PRO C . n +C 1 29 ALA 29 29 29 ALA ALA C . n +C 1 30 PRO 30 30 30 PRO PRO C . n +C 1 31 THR 31 31 31 THR THR C . n +C 1 32 GLY 32 32 32 GLY GLY C . n +C 1 33 LYS 33 33 33 LYS LYS C . n +C 1 34 ILE 34 34 34 ILE ILE C . n +C 1 35 PHE 35 35 35 PHE PHE C . n +C 1 36 VAL 36 36 36 VAL VAL C . n +C 1 37 SER 37 37 37 SER SER C . n +C 1 38 VAL 38 38 38 VAL VAL C . n +C 1 39 TYR 39 39 39 TYR TYR C . n +C 1 40 ASN 40 40 40 ASN ASN C . n +C 1 41 ILE 41 41 41 ILE ILE C . n +C 1 42 GLN 42 42 42 GLN GLN C . n +C 1 43 ASP 43 43 43 ASP ASP C . n +C 1 44 GLU 44 44 44 GLU GLU C . n +C 1 45 THR 45 45 45 THR THR C . n +C 1 46 GLY 46 46 46 GLY GLY C . n +C 1 47 GLN 47 47 47 GLN GLN C . n +C 1 48 PHE 48 48 48 PHE PHE C . n +C 1 49 LYS 49 49 49 LYS LYS C . n +C 1 50 PRO 50 50 50 PRO PRO C . n +C 1 51 TYR 51 51 51 TYR TYR C . n +C 1 52 PRO 52 52 52 PRO PRO C . n +C 1 53 ALA 53 53 53 ALA ALA C . n +C 1 54 SER 54 54 54 SER SER C . n +C 1 55 ASN 55 55 55 ASN ASN C . n +C 1 56 PHE 56 56 56 PHE PHE C . n +C 1 57 SER 57 57 57 SER SER C . n +C 1 58 THR 58 58 58 THR THR C . n +C 1 59 ALA 59 59 59 ALA ALA C . n +C 1 60 VAL 60 60 60 VAL VAL C . n +C 1 61 PRO 61 61 61 PRO PRO C . n +C 1 62 GLN 62 62 62 GLN GLN C . n +C 1 63 SER 63 63 63 SER SER C . n +C 1 64 ALA 64 64 64 ALA ALA C . n +C 1 65 THR 65 65 65 THR THR C . n +C 1 66 ALA 66 66 66 ALA ALA C . n +C 1 67 MET 67 67 67 MET MET C . n +C 1 68 LEU 68 68 68 LEU LEU C . n +C 1 69 VAL 69 69 69 VAL VAL C . n +C 1 70 THR 70 70 70 THR THR C . n +C 1 71 ALA 71 71 71 ALA ALA C . n +C 1 72 LEU 72 72 72 LEU LEU C . n +C 1 73 LYS 73 73 73 LYS LYS C . n +C 1 74 ASP 74 74 74 ASP ASP C . n +C 1 75 SER 75 75 75 SER SER C . n +C 1 76 ARG 76 76 76 ARG ARG C . n +C 1 77 TRP 77 77 77 TRP TRP C . n +C 1 78 PHE 78 78 78 PHE PHE C . n +C 1 79 ILE 79 79 79 ILE ILE C . n +C 1 80 PRO 80 80 80 PRO PRO C . n +C 1 81 LEU 81 81 81 LEU LEU C . n +C 1 82 GLU 82 82 82 GLU GLU C . n +C 1 83 ARG 83 83 83 ARG ARG C . n +C 1 84 GLN 84 84 84 GLN GLN C . n +C 1 85 GLY 85 85 85 GLY GLY C . n +C 1 86 LEU 86 86 86 LEU LEU C . n +C 1 87 GLN 87 87 87 GLN GLN C . n +C 1 88 ASN 88 88 88 ASN ASN C . n +C 1 89 LEU 89 89 89 LEU LEU C . n +C 1 90 LEU 90 90 90 LEU LEU C . n +C 1 91 ASN 91 91 91 ASN ASN C . n +C 1 92 GLU 92 92 92 GLU GLU C . n +C 1 93 ARG 93 93 93 ARG ARG C . n +C 1 94 LYS 94 94 94 LYS LYS C . n +C 1 95 ILE 95 95 95 ILE ILE C . n +C 1 96 ILE 96 96 96 ILE ILE C . n +C 1 97 ARG 97 97 97 ARG ARG C . n +C 1 98 ALA 98 98 98 ALA ALA C . n +C 1 99 ALA 99 99 99 ALA ALA C . n +C 1 100 GLN 100 100 100 GLN GLN C . n +C 1 101 GLU 101 101 101 GLU GLU C . n +C 1 102 ASN 102 102 102 ASN ASN C . n +C 1 103 GLY 103 103 103 GLY GLY C . n +C 1 104 THR 104 104 104 THR THR C . n +C 1 105 VAL 105 105 105 VAL VAL C . n +C 1 106 ALA 106 106 106 ALA ALA C . n +C 1 107 ILE 107 107 107 ILE ILE C . n +C 1 108 ASN 108 108 108 ASN ASN C . n +C 1 109 ASN 109 109 109 ASN ASN C . n +C 1 110 ARG 110 110 110 ARG ARG C . n +C 1 111 ILE 111 111 111 ILE ILE C . n +C 1 112 PRO 112 112 112 PRO PRO C . n +C 1 113 LEU 113 113 113 LEU LEU C . n +C 1 114 GLN 114 114 114 GLN GLN C . n +C 1 115 SER 115 115 115 SER SER C . n +C 1 116 LEU 116 116 116 LEU LEU C . n +C 1 117 THR 117 117 117 THR THR C . n +C 1 118 ALA 118 118 118 ALA ALA C . n +C 1 119 ALA 119 119 119 ALA ALA C . n +C 1 120 ASN 120 120 120 ASN ASN C . n +C 1 121 ILE 121 121 121 ILE ILE C . n +C 1 122 MET 122 122 122 MET MET C . n +C 1 123 VAL 123 123 123 VAL VAL C . n +C 1 124 GLU 124 124 124 GLU GLU C . n +C 1 125 GLY 125 125 125 GLY GLY C . n +C 1 126 SER 126 126 126 SER SER C . n +C 1 127 ILE 127 127 127 ILE ILE C . n +C 1 128 ILE 128 128 128 ILE ILE C . n +C 1 129 GLY 129 129 129 GLY GLY C . n +C 1 130 TYR 130 130 130 TYR TYR C . n +C 1 131 GLU 131 131 131 GLU GLU C . n +C 1 132 SER 132 132 132 SER SER C . n +C 1 133 ASN 133 133 133 ASN ASN C . n +C 1 134 VAL 134 134 134 VAL VAL C . n +C 1 135 LYS 135 135 135 LYS LYS C . n +C 1 136 SER 136 136 136 SER SER C . n +C 1 137 GLY 137 137 137 GLY GLY C . n +C 1 138 GLY 138 138 138 GLY GLY C . n +C 1 139 VAL 139 139 139 VAL VAL C . n +C 1 140 GLY 140 140 140 GLY GLY C . n +C 1 141 ALA 141 141 141 ALA ALA C . n +C 1 142 ARG 142 142 142 ARG ARG C . n +C 1 143 TYR 143 143 143 TYR TYR C . n +C 1 144 PHE 144 144 ? ? ? C . n +C 1 145 GLY 145 145 145 GLY GLY C . n +C 1 146 ILE 146 146 146 ILE ILE C . n +C 1 147 GLY 147 147 147 GLY GLY C . n +C 1 148 ALA 148 148 148 ALA ALA C . n +C 1 149 ASP 149 149 149 ASP ASP C . n +C 1 150 THR 150 150 150 THR THR C . n +C 1 151 GLN 151 151 151 GLN GLN C . n +C 1 152 TYR 152 152 152 TYR TYR C . n +C 1 153 GLN 153 153 153 GLN GLN C . n +C 1 154 LEU 154 154 154 LEU LEU C . n +C 1 155 ASP 155 155 155 ASP ASP C . n +C 1 156 GLN 156 156 156 GLN GLN C . n +C 1 157 ILE 157 157 157 ILE ILE C . n +C 1 158 ALA 158 158 158 ALA ALA C . n +C 1 159 VAL 159 159 159 VAL VAL C . n +C 1 160 ASN 160 160 160 ASN ASN C . n +C 1 161 LEU 161 161 161 LEU LEU C . n +C 1 162 ARG 162 162 162 ARG ARG C . n +C 1 163 VAL 163 163 163 VAL VAL C . n +C 1 164 VAL 164 164 164 VAL VAL C . n +C 1 165 ASN 165 165 165 ASN ASN C . n +C 1 166 VAL 166 166 166 VAL VAL C . n +C 1 167 SER 167 167 167 SER SER C . n +C 1 168 THR 168 168 168 THR THR C . n +C 1 169 GLY 169 169 169 GLY GLY C . n +C 1 170 GLU 170 170 170 GLU GLU C . n +C 1 171 ILE 171 171 171 ILE ILE C . n +C 1 172 LEU 172 172 172 LEU LEU C . n +C 1 173 SER 173 173 173 SER SER C . n +C 1 174 SER 174 174 174 SER SER C . n +C 1 175 VAL 175 175 175 VAL VAL C . n +C 1 176 ASN 176 176 176 ASN ASN C . n +C 1 177 THR 177 177 177 THR THR C . n +C 1 178 SER 178 178 178 SER SER C . n +C 1 179 LYS 179 179 179 LYS LYS C . n +C 1 180 THR 180 180 180 THR THR C . n +C 1 181 ILE 181 181 181 ILE ILE C . n +C 1 182 LEU 182 182 182 LEU LEU C . n +C 1 183 SER 183 183 183 SER SER C . n +C 1 184 TYR 184 184 184 TYR TYR C . n +C 1 185 GLU 185 185 185 GLU GLU C . n +C 1 186 VAL 186 186 186 VAL VAL C . n +C 1 187 GLN 187 187 187 GLN GLN C . n +C 1 188 ALA 188 188 188 ALA ALA C . n +C 1 189 GLY 189 189 189 GLY GLY C . n +C 1 190 VAL 190 190 190 VAL VAL C . n +C 1 191 PHE 191 191 191 PHE PHE C . n +C 1 192 ARG 192 192 ? ? ? C . n +C 1 193 PHE 193 193 ? ? ? C . n +C 1 194 ILE 194 194 ? ? ? C . n +C 1 195 ASP 195 195 ? ? ? C . n +C 1 196 TYR 196 196 ? ? ? C . n +C 1 197 GLN 197 197 ? ? ? C . n +C 1 198 ARG 198 198 ? ? ? C . n +C 1 199 LEU 199 199 ? ? ? C . n +C 1 200 LEU 200 200 200 LEU LEU C . n +C 1 201 GLU 201 201 201 GLU GLU C . n +C 1 202 GLY 202 202 202 GLY GLY C . n +C 1 203 GLU 203 203 203 GLU GLU C . n +C 1 204 VAL 204 204 204 VAL VAL C . n +C 1 205 GLY 205 205 205 GLY GLY C . n +C 1 206 TYR 206 206 206 TYR TYR C . n +C 1 207 THR 207 207 207 THR THR C . n +C 1 208 SER 208 208 208 SER SER C . n +C 1 209 ASN 209 209 209 ASN ASN C . n +C 1 210 GLU 210 210 210 GLU GLU C . n +C 1 211 PRO 211 211 211 PRO PRO C . n +C 1 212 VAL 212 212 212 VAL VAL C . n +C 1 213 MET 213 213 213 MET MET C . n +C 1 214 LEU 214 214 214 LEU LEU C . n +C 1 215 CYS 215 215 215 CYS CYS C . n +C 1 216 LEU 216 216 216 LEU LEU C . n +C 1 217 MET 217 217 217 MET MET C . n +C 1 218 SER 218 218 218 SER SER C . n +C 1 219 ALA 219 219 219 ALA ALA C . n +C 1 220 ILE 220 220 220 ILE ILE C . n +C 1 221 GLU 221 221 221 GLU GLU C . n +C 1 222 THR 222 222 222 THR THR C . n +C 1 223 GLY 223 223 223 GLY GLY C . n +C 1 224 VAL 224 224 224 VAL VAL C . n +C 1 225 ILE 225 225 225 ILE ILE C . n +C 1 226 PHE 226 226 226 PHE PHE C . n +C 1 227 LEU 227 227 227 LEU LEU C . n +C 1 228 ILE 228 228 228 ILE ILE C . n +C 1 229 ASN 229 229 229 ASN ASN C . n +C 1 230 ASP 230 230 230 ASP ASP C . n +C 1 231 GLY 231 231 231 GLY GLY C . n +C 1 232 ILE 232 232 232 ILE ILE C . n +C 1 233 ASP 233 233 233 ASP ASP C . n +C 1 234 ARG 234 234 234 ARG ARG C . n +C 1 235 GLY 235 235 235 GLY GLY C . n +C 1 236 LEU 236 236 236 LEU LEU C . n +C 1 237 TRP 237 237 237 TRP TRP C . n +C 1 238 ASP 238 238 238 ASP ASP C . n +C 1 239 LEU 239 239 239 LEU LEU C . n +C 1 240 GLN 240 240 240 GLN GLN C . n +C 1 241 ASN 241 241 241 ASN ASN C . n +C 1 242 LYS 242 242 242 LYS LYS C . n +C 1 243 ALA 243 243 243 ALA ALA C . n +C 1 244 GLU 244 244 244 GLU GLU C . n +C 1 245 ARG 245 245 245 ARG ARG C . n +C 1 246 GLN 246 246 246 GLN GLN C . n +C 1 247 ASN 247 247 247 ASN ASN C . n +C 1 248 ASP 248 248 248 ASP ASP C . n +C 1 249 ILE 249 249 249 ILE ILE C . n +C 1 250 LEU 250 250 250 LEU LEU C . n +C 1 251 VAL 251 251 251 VAL VAL C . n +C 1 252 LYS 252 252 252 LYS LYS C . n +C 1 253 TYR 253 253 253 TYR TYR C . n +C 1 254 ARG 254 254 254 ARG ARG C . n +C 1 255 HIS 255 255 255 HIS HIS C . n +C 1 256 MET 256 256 256 MET MET C . n +C 1 257 SER 257 257 257 SER SER C . n +C 1 258 VAL 258 258 ? ? ? C . n +C 1 259 PRO 259 259 ? ? ? C . n +C 1 260 PRO 260 260 ? ? ? C . n +C 1 261 GLU 261 261 ? ? ? C . n +C 1 262 SER 262 262 ? ? ? C . n +D 1 1 CYS 1 1 ? ? ? D . n +D 1 2 LEU 2 2 2 LEU LEU D . n +D 1 3 THR 3 3 3 THR THR D . n +D 1 4 ALA 4 4 4 ALA ALA D . n +D 1 5 PRO 5 5 5 PRO PRO D . n +D 1 6 PRO 6 6 6 PRO PRO D . n +D 1 7 LYS 7 7 7 LYS LYS D . n +D 1 8 GLU 8 8 8 GLU GLU D . n +D 1 9 ALA 9 9 9 ALA ALA D . n +D 1 10 ALA 10 10 10 ALA ALA D . n +D 1 11 ARG 11 11 11 ARG ARG D . n +D 1 12 PRO 12 12 12 PRO PRO D . n +D 1 13 THR 13 13 13 THR THR D . n +D 1 14 LEU 14 14 14 LEU LEU D . n +D 1 15 MET 15 15 15 MET MET D . n +D 1 16 PRO 16 16 16 PRO PRO D . n +D 1 17 ARG 17 17 17 ARG ARG D . n +D 1 18 ALA 18 18 18 ALA ALA D . n +D 1 19 GLN 19 19 19 GLN GLN D . n +D 1 20 SER 20 20 20 SER SER D . n +D 1 21 TYR 21 21 21 TYR TYR D . n +D 1 22 LYS 22 22 22 LYS LYS D . n +D 1 23 ASP 23 23 23 ASP ASP D . n +D 1 24 LEU 24 24 24 LEU LEU D . n +D 1 25 THR 25 25 25 THR THR D . n +D 1 26 HIS 26 26 26 HIS HIS D . n +D 1 27 LEU 27 27 27 LEU LEU D . n +D 1 28 PRO 28 28 28 PRO PRO D . n +D 1 29 ALA 29 29 29 ALA ALA D . n +D 1 30 PRO 30 30 30 PRO PRO D . n +D 1 31 THR 31 31 31 THR THR D . n +D 1 32 GLY 32 32 32 GLY GLY D . n +D 1 33 LYS 33 33 33 LYS LYS D . n +D 1 34 ILE 34 34 34 ILE ILE D . n +D 1 35 PHE 35 35 35 PHE PHE D . n +D 1 36 VAL 36 36 36 VAL VAL D . n +D 1 37 SER 37 37 37 SER SER D . n +D 1 38 VAL 38 38 38 VAL VAL D . n +D 1 39 TYR 39 39 39 TYR TYR D . n +D 1 40 ASN 40 40 40 ASN ASN D . n +D 1 41 ILE 41 41 41 ILE ILE D . n +D 1 42 GLN 42 42 42 GLN GLN D . n +D 1 43 ASP 43 43 43 ASP ASP D . n +D 1 44 GLU 44 44 44 GLU GLU D . n +D 1 45 THR 45 45 45 THR THR D . n +D 1 46 GLY 46 46 46 GLY GLY D . n +D 1 47 GLN 47 47 47 GLN GLN D . n +D 1 48 PHE 48 48 48 PHE PHE D . n +D 1 49 LYS 49 49 49 LYS LYS D . n +D 1 50 PRO 50 50 50 PRO PRO D . n +D 1 51 TYR 51 51 51 TYR TYR D . n +D 1 52 PRO 52 52 52 PRO PRO D . n +D 1 53 ALA 53 53 53 ALA ALA D . n +D 1 54 SER 54 54 54 SER SER D . n +D 1 55 ASN 55 55 55 ASN ASN D . n +D 1 56 PHE 56 56 56 PHE PHE D . n +D 1 57 SER 57 57 57 SER SER D . n +D 1 58 THR 58 58 58 THR THR D . n +D 1 59 ALA 59 59 59 ALA ALA D . n +D 1 60 VAL 60 60 60 VAL VAL D . n +D 1 61 PRO 61 61 61 PRO PRO D . n +D 1 62 GLN 62 62 62 GLN GLN D . n +D 1 63 SER 63 63 63 SER SER D . n +D 1 64 ALA 64 64 64 ALA ALA D . n +D 1 65 THR 65 65 65 THR THR D . n +D 1 66 ALA 66 66 66 ALA ALA D . n +D 1 67 MET 67 67 67 MET MET D . n +D 1 68 LEU 68 68 68 LEU LEU D . n +D 1 69 VAL 69 69 69 VAL VAL D . n +D 1 70 THR 70 70 70 THR THR D . n +D 1 71 ALA 71 71 71 ALA ALA D . n +D 1 72 LEU 72 72 72 LEU LEU D . n +D 1 73 LYS 73 73 73 LYS LYS D . n +D 1 74 ASP 74 74 74 ASP ASP D . n +D 1 75 SER 75 75 75 SER SER D . n +D 1 76 ARG 76 76 76 ARG ARG D . n +D 1 77 TRP 77 77 77 TRP TRP D . n +D 1 78 PHE 78 78 78 PHE PHE D . n +D 1 79 ILE 79 79 79 ILE ILE D . n +D 1 80 PRO 80 80 80 PRO PRO D . n +D 1 81 LEU 81 81 81 LEU LEU D . n +D 1 82 GLU 82 82 82 GLU GLU D . n +D 1 83 ARG 83 83 83 ARG ARG D . n +D 1 84 GLN 84 84 84 GLN GLN D . n +D 1 85 GLY 85 85 85 GLY GLY D . n +D 1 86 LEU 86 86 86 LEU LEU D . n +D 1 87 GLN 87 87 87 GLN GLN D . n +D 1 88 ASN 88 88 88 ASN ASN D . n +D 1 89 LEU 89 89 89 LEU LEU D . n +D 1 90 LEU 90 90 90 LEU LEU D . n +D 1 91 ASN 91 91 91 ASN ASN D . n +D 1 92 GLU 92 92 92 GLU GLU D . n +D 1 93 ARG 93 93 93 ARG ARG D . n +D 1 94 LYS 94 94 94 LYS LYS D . n +D 1 95 ILE 95 95 95 ILE ILE D . n +D 1 96 ILE 96 96 96 ILE ILE D . n +D 1 97 ARG 97 97 97 ARG ARG D . n +D 1 98 ALA 98 98 98 ALA ALA D . n +D 1 99 ALA 99 99 99 ALA ALA D . n +D 1 100 GLN 100 100 100 GLN GLN D . n +D 1 101 GLU 101 101 101 GLU GLU D . n +D 1 102 ASN 102 102 102 ASN ASN D . n +D 1 103 GLY 103 103 103 GLY GLY D . n +D 1 104 THR 104 104 104 THR THR D . n +D 1 105 VAL 105 105 105 VAL VAL D . n +D 1 106 ALA 106 106 106 ALA ALA D . n +D 1 107 ILE 107 107 107 ILE ILE D . n +D 1 108 ASN 108 108 108 ASN ASN D . n +D 1 109 ASN 109 109 109 ASN ASN D . n +D 1 110 ARG 110 110 110 ARG ARG D . n +D 1 111 ILE 111 111 111 ILE ILE D . n +D 1 112 PRO 112 112 112 PRO PRO D . n +D 1 113 LEU 113 113 113 LEU LEU D . n +D 1 114 GLN 114 114 114 GLN GLN D . n +D 1 115 SER 115 115 115 SER SER D . n +D 1 116 LEU 116 116 116 LEU LEU D . n +D 1 117 THR 117 117 117 THR THR D . n +D 1 118 ALA 118 118 118 ALA ALA D . n +D 1 119 ALA 119 119 119 ALA ALA D . n +D 1 120 ASN 120 120 120 ASN ASN D . n +D 1 121 ILE 121 121 121 ILE ILE D . n +D 1 122 MET 122 122 122 MET MET D . n +D 1 123 VAL 123 123 123 VAL VAL D . n +D 1 124 GLU 124 124 124 GLU GLU D . n +D 1 125 GLY 125 125 125 GLY GLY D . n +D 1 126 SER 126 126 126 SER SER D . n +D 1 127 ILE 127 127 127 ILE ILE D . n +D 1 128 ILE 128 128 128 ILE ILE D . n +D 1 129 GLY 129 129 129 GLY GLY D . n +D 1 130 TYR 130 130 130 TYR TYR D . n +D 1 131 GLU 131 131 131 GLU GLU D . n +D 1 132 SER 132 132 132 SER SER D . n +D 1 133 ASN 133 133 133 ASN ASN D . n +D 1 134 VAL 134 134 134 VAL VAL D . n +D 1 135 LYS 135 135 135 LYS LYS D . n +D 1 136 SER 136 136 136 SER SER D . n +D 1 137 GLY 137 137 137 GLY GLY D . n +D 1 138 GLY 138 138 138 GLY GLY D . n +D 1 139 VAL 139 139 139 VAL VAL D . n +D 1 140 GLY 140 140 140 GLY GLY D . n +D 1 141 ALA 141 141 141 ALA ALA D . n +D 1 142 ARG 142 142 142 ARG ARG D . n +D 1 143 TYR 143 143 143 TYR TYR D . n +D 1 144 PHE 144 144 ? ? ? D . n +D 1 145 GLY 145 145 145 GLY GLY D . n +D 1 146 ILE 146 146 146 ILE ILE D . n +D 1 147 GLY 147 147 147 GLY GLY D . n +D 1 148 ALA 148 148 148 ALA ALA D . n +D 1 149 ASP 149 149 149 ASP ASP D . n +D 1 150 THR 150 150 150 THR THR D . n +D 1 151 GLN 151 151 151 GLN GLN D . n +D 1 152 TYR 152 152 152 TYR TYR D . n +D 1 153 GLN 153 153 153 GLN GLN D . n +D 1 154 LEU 154 154 154 LEU LEU D . n +D 1 155 ASP 155 155 155 ASP ASP D . n +D 1 156 GLN 156 156 156 GLN GLN D . n +D 1 157 ILE 157 157 157 ILE ILE D . n +D 1 158 ALA 158 158 158 ALA ALA D . n +D 1 159 VAL 159 159 159 VAL VAL D . n +D 1 160 ASN 160 160 160 ASN ASN D . n +D 1 161 LEU 161 161 161 LEU LEU D . n +D 1 162 ARG 162 162 162 ARG ARG D . n +D 1 163 VAL 163 163 163 VAL VAL D . n +D 1 164 VAL 164 164 164 VAL VAL D . n +D 1 165 ASN 165 165 165 ASN ASN D . n +D 1 166 VAL 166 166 166 VAL VAL D . n +D 1 167 SER 167 167 167 SER SER D . n +D 1 168 THR 168 168 168 THR THR D . n +D 1 169 GLY 169 169 169 GLY GLY D . n +D 1 170 GLU 170 170 170 GLU GLU D . n +D 1 171 ILE 171 171 171 ILE ILE D . n +D 1 172 LEU 172 172 172 LEU LEU D . n +D 1 173 SER 173 173 173 SER SER D . n +D 1 174 SER 174 174 174 SER SER D . n +D 1 175 VAL 175 175 175 VAL VAL D . n +D 1 176 ASN 176 176 176 ASN ASN D . n +D 1 177 THR 177 177 177 THR THR D . n +D 1 178 SER 178 178 178 SER SER D . n +D 1 179 LYS 179 179 179 LYS LYS D . n +D 1 180 THR 180 180 180 THR THR D . n +D 1 181 ILE 181 181 181 ILE ILE D . n +D 1 182 LEU 182 182 182 LEU LEU D . n +D 1 183 SER 183 183 183 SER SER D . n +D 1 184 TYR 184 184 184 TYR TYR D . n +D 1 185 GLU 185 185 185 GLU GLU D . n +D 1 186 VAL 186 186 186 VAL VAL D . n +D 1 187 GLN 187 187 187 GLN GLN D . n +D 1 188 ALA 188 188 188 ALA ALA D . n +D 1 189 GLY 189 189 189 GLY GLY D . n +D 1 190 VAL 190 190 190 VAL VAL D . n +D 1 191 PHE 191 191 191 PHE PHE D . n +D 1 192 ARG 192 192 192 ARG ARG D . n +D 1 193 PHE 193 193 ? ? ? D . n +D 1 194 ILE 194 194 ? ? ? D . n +D 1 195 ASP 195 195 ? ? ? D . n +D 1 196 TYR 196 196 ? ? ? D . n +D 1 197 GLN 197 197 ? ? ? D . n +D 1 198 ARG 198 198 ? ? ? D . n +D 1 199 LEU 199 199 ? ? ? D . n +D 1 200 LEU 200 200 200 LEU LEU D . n +D 1 201 GLU 201 201 201 GLU GLU D . n +D 1 202 GLY 202 202 202 GLY GLY D . n +D 1 203 GLU 203 203 203 GLU GLU D . n +D 1 204 VAL 204 204 204 VAL VAL D . n +D 1 205 GLY 205 205 205 GLY GLY D . n +D 1 206 TYR 206 206 206 TYR TYR D . n +D 1 207 THR 207 207 207 THR THR D . n +D 1 208 SER 208 208 208 SER SER D . n +D 1 209 ASN 209 209 209 ASN ASN D . n +D 1 210 GLU 210 210 210 GLU GLU D . n +D 1 211 PRO 211 211 211 PRO PRO D . n +D 1 212 VAL 212 212 212 VAL VAL D . n +D 1 213 MET 213 213 213 MET MET D . n +D 1 214 LEU 214 214 214 LEU LEU D . n +D 1 215 CYS 215 215 215 CYS CYS D . n +D 1 216 LEU 216 216 216 LEU LEU D . n +D 1 217 MET 217 217 217 MET MET D . n +D 1 218 SER 218 218 218 SER SER D . n +D 1 219 ALA 219 219 219 ALA ALA D . n +D 1 220 ILE 220 220 220 ILE ILE D . n +D 1 221 GLU 221 221 221 GLU GLU D . n +D 1 222 THR 222 222 222 THR THR D . n +D 1 223 GLY 223 223 223 GLY GLY D . n +D 1 224 VAL 224 224 224 VAL VAL D . n +D 1 225 ILE 225 225 225 ILE ILE D . n +D 1 226 PHE 226 226 226 PHE PHE D . n +D 1 227 LEU 227 227 227 LEU LEU D . n +D 1 228 ILE 228 228 228 ILE ILE D . n +D 1 229 ASN 229 229 229 ASN ASN D . n +D 1 230 ASP 230 230 230 ASP ASP D . n +D 1 231 GLY 231 231 231 GLY GLY D . n +D 1 232 ILE 232 232 232 ILE ILE D . n +D 1 233 ASP 233 233 233 ASP ASP D . n +D 1 234 ARG 234 234 234 ARG ARG D . n +D 1 235 GLY 235 235 235 GLY GLY D . n +D 1 236 LEU 236 236 236 LEU LEU D . n +D 1 237 TRP 237 237 237 TRP TRP D . n +D 1 238 ASP 238 238 238 ASP ASP D . n +D 1 239 LEU 239 239 239 LEU LEU D . n +D 1 240 GLN 240 240 240 GLN GLN D . n +D 1 241 ASN 241 241 241 ASN ASN D . n +D 1 242 LYS 242 242 242 LYS LYS D . n +D 1 243 ALA 243 243 243 ALA ALA D . n +D 1 244 GLU 244 244 244 GLU GLU D . n +D 1 245 ARG 245 245 245 ARG ARG D . n +D 1 246 GLN 246 246 246 GLN GLN D . n +D 1 247 ASN 247 247 247 ASN ASN D . n +D 1 248 ASP 248 248 248 ASP ASP D . n +D 1 249 ILE 249 249 249 ILE ILE D . n +D 1 250 LEU 250 250 250 LEU LEU D . n +D 1 251 VAL 251 251 251 VAL VAL D . n +D 1 252 LYS 252 252 252 LYS LYS D . n +D 1 253 TYR 253 253 253 TYR TYR D . n +D 1 254 ARG 254 254 254 ARG ARG D . n +D 1 255 HIS 255 255 255 HIS HIS D . n +D 1 256 MET 256 256 256 MET MET D . n +D 1 257 SER 257 257 257 SER SER D . n +D 1 258 VAL 258 258 ? ? ? D . n +D 1 259 PRO 259 259 ? ? ? D . n +D 1 260 PRO 260 260 ? ? ? D . n +D 1 261 GLU 261 261 ? ? ? D . n +D 1 262 SER 262 262 ? ? ? D . n +E 1 1 CYS 1 1 ? ? ? E . n +E 1 2 LEU 2 2 2 LEU LEU E . n +E 1 3 THR 3 3 3 THR THR E . n +E 1 4 ALA 4 4 4 ALA ALA E . n +E 1 5 PRO 5 5 5 PRO PRO E . n +E 1 6 PRO 6 6 6 PRO PRO E . n +E 1 7 LYS 7 7 7 LYS LYS E . n +E 1 8 GLU 8 8 8 GLU GLU E . n +E 1 9 ALA 9 9 9 ALA ALA E . n +E 1 10 ALA 10 10 10 ALA ALA E . n +E 1 11 ARG 11 11 11 ARG ARG E . n +E 1 12 PRO 12 12 12 PRO PRO E . n +E 1 13 THR 13 13 13 THR THR E . n +E 1 14 LEU 14 14 14 LEU LEU E . n +E 1 15 MET 15 15 15 MET MET E . n +E 1 16 PRO 16 16 16 PRO PRO E . n +E 1 17 ARG 17 17 17 ARG ARG E . n +E 1 18 ALA 18 18 18 ALA ALA E . n +E 1 19 GLN 19 19 19 GLN GLN E . n +E 1 20 SER 20 20 20 SER SER E . n +E 1 21 TYR 21 21 21 TYR TYR E . n +E 1 22 LYS 22 22 22 LYS LYS E . n +E 1 23 ASP 23 23 23 ASP ASP E . n +E 1 24 LEU 24 24 24 LEU LEU E . n +E 1 25 THR 25 25 25 THR THR E . n +E 1 26 HIS 26 26 26 HIS HIS E . n +E 1 27 LEU 27 27 27 LEU LEU E . n +E 1 28 PRO 28 28 28 PRO PRO E . n +E 1 29 ALA 29 29 29 ALA ALA E . n +E 1 30 PRO 30 30 30 PRO PRO E . n +E 1 31 THR 31 31 31 THR THR E . n +E 1 32 GLY 32 32 32 GLY GLY E . n +E 1 33 LYS 33 33 33 LYS LYS E . n +E 1 34 ILE 34 34 34 ILE ILE E . n +E 1 35 PHE 35 35 35 PHE PHE E . n +E 1 36 VAL 36 36 36 VAL VAL E . n +E 1 37 SER 37 37 37 SER SER E . n +E 1 38 VAL 38 38 38 VAL VAL E . n +E 1 39 TYR 39 39 39 TYR TYR E . n +E 1 40 ASN 40 40 40 ASN ASN E . n +E 1 41 ILE 41 41 41 ILE ILE E . n +E 1 42 GLN 42 42 42 GLN GLN E . n +E 1 43 ASP 43 43 43 ASP ASP E . n +E 1 44 GLU 44 44 44 GLU GLU E . n +E 1 45 THR 45 45 45 THR THR E . n +E 1 46 GLY 46 46 46 GLY GLY E . n +E 1 47 GLN 47 47 47 GLN GLN E . n +E 1 48 PHE 48 48 48 PHE PHE E . n +E 1 49 LYS 49 49 49 LYS LYS E . n +E 1 50 PRO 50 50 50 PRO PRO E . n +E 1 51 TYR 51 51 51 TYR TYR E . n +E 1 52 PRO 52 52 52 PRO PRO E . n +E 1 53 ALA 53 53 53 ALA ALA E . n +E 1 54 SER 54 54 54 SER SER E . n +E 1 55 ASN 55 55 55 ASN ASN E . n +E 1 56 PHE 56 56 56 PHE PHE E . n +E 1 57 SER 57 57 57 SER SER E . n +E 1 58 THR 58 58 58 THR THR E . n +E 1 59 ALA 59 59 59 ALA ALA E . n +E 1 60 VAL 60 60 60 VAL VAL E . n +E 1 61 PRO 61 61 61 PRO PRO E . n +E 1 62 GLN 62 62 62 GLN GLN E . n +E 1 63 SER 63 63 63 SER SER E . n +E 1 64 ALA 64 64 64 ALA ALA E . n +E 1 65 THR 65 65 65 THR THR E . n +E 1 66 ALA 66 66 66 ALA ALA E . n +E 1 67 MET 67 67 67 MET MET E . n +E 1 68 LEU 68 68 68 LEU LEU E . n +E 1 69 VAL 69 69 69 VAL VAL E . n +E 1 70 THR 70 70 70 THR THR E . n +E 1 71 ALA 71 71 71 ALA ALA E . n +E 1 72 LEU 72 72 72 LEU LEU E . n +E 1 73 LYS 73 73 73 LYS LYS E . n +E 1 74 ASP 74 74 74 ASP ASP E . n +E 1 75 SER 75 75 75 SER SER E . n +E 1 76 ARG 76 76 76 ARG ARG E . n +E 1 77 TRP 77 77 77 TRP TRP E . n +E 1 78 PHE 78 78 78 PHE PHE E . n +E 1 79 ILE 79 79 79 ILE ILE E . n +E 1 80 PRO 80 80 80 PRO PRO E . n +E 1 81 LEU 81 81 81 LEU LEU E . n +E 1 82 GLU 82 82 82 GLU GLU E . n +E 1 83 ARG 83 83 83 ARG ARG E . n +E 1 84 GLN 84 84 84 GLN GLN E . n +E 1 85 GLY 85 85 85 GLY GLY E . n +E 1 86 LEU 86 86 86 LEU LEU E . n +E 1 87 GLN 87 87 87 GLN GLN E . n +E 1 88 ASN 88 88 88 ASN ASN E . n +E 1 89 LEU 89 89 89 LEU LEU E . n +E 1 90 LEU 90 90 90 LEU LEU E . n +E 1 91 ASN 91 91 91 ASN ASN E . n +E 1 92 GLU 92 92 92 GLU GLU E . n +E 1 93 ARG 93 93 93 ARG ARG E . n +E 1 94 LYS 94 94 94 LYS LYS E . n +E 1 95 ILE 95 95 95 ILE ILE E . n +E 1 96 ILE 96 96 96 ILE ILE E . n +E 1 97 ARG 97 97 97 ARG ARG E . n +E 1 98 ALA 98 98 98 ALA ALA E . n +E 1 99 ALA 99 99 99 ALA ALA E . n +E 1 100 GLN 100 100 100 GLN GLN E . n +E 1 101 GLU 101 101 101 GLU GLU E . n +E 1 102 ASN 102 102 102 ASN ASN E . n +E 1 103 GLY 103 103 103 GLY GLY E . n +E 1 104 THR 104 104 104 THR THR E . n +E 1 105 VAL 105 105 105 VAL VAL E . n +E 1 106 ALA 106 106 106 ALA ALA E . n +E 1 107 ILE 107 107 107 ILE ILE E . n +E 1 108 ASN 108 108 108 ASN ASN E . n +E 1 109 ASN 109 109 109 ASN ASN E . n +E 1 110 ARG 110 110 110 ARG ARG E . n +E 1 111 ILE 111 111 111 ILE ILE E . n +E 1 112 PRO 112 112 112 PRO PRO E . n +E 1 113 LEU 113 113 113 LEU LEU E . n +E 1 114 GLN 114 114 114 GLN GLN E . n +E 1 115 SER 115 115 115 SER SER E . n +E 1 116 LEU 116 116 116 LEU LEU E . n +E 1 117 THR 117 117 117 THR THR E . n +E 1 118 ALA 118 118 118 ALA ALA E . n +E 1 119 ALA 119 119 119 ALA ALA E . n +E 1 120 ASN 120 120 120 ASN ASN E . n +E 1 121 ILE 121 121 121 ILE ILE E . n +E 1 122 MET 122 122 122 MET MET E . n +E 1 123 VAL 123 123 123 VAL VAL E . n +E 1 124 GLU 124 124 124 GLU GLU E . n +E 1 125 GLY 125 125 125 GLY GLY E . n +E 1 126 SER 126 126 126 SER SER E . n +E 1 127 ILE 127 127 127 ILE ILE E . n +E 1 128 ILE 128 128 128 ILE ILE E . n +E 1 129 GLY 129 129 129 GLY GLY E . n +E 1 130 TYR 130 130 130 TYR TYR E . n +E 1 131 GLU 131 131 131 GLU GLU E . n +E 1 132 SER 132 132 132 SER SER E . n +E 1 133 ASN 133 133 133 ASN ASN E . n +E 1 134 VAL 134 134 134 VAL VAL E . n +E 1 135 LYS 135 135 135 LYS LYS E . n +E 1 136 SER 136 136 136 SER SER E . n +E 1 137 GLY 137 137 137 GLY GLY E . n +E 1 138 GLY 138 138 138 GLY GLY E . n +E 1 139 VAL 139 139 139 VAL VAL E . n +E 1 140 GLY 140 140 140 GLY GLY E . n +E 1 141 ALA 141 141 141 ALA ALA E . n +E 1 142 ARG 142 142 142 ARG ARG E . n +E 1 143 TYR 143 143 143 TYR TYR E . n +E 1 144 PHE 144 144 ? ? ? E . n +E 1 145 GLY 145 145 145 GLY GLY E . n +E 1 146 ILE 146 146 146 ILE ILE E . n +E 1 147 GLY 147 147 147 GLY GLY E . n +E 1 148 ALA 148 148 148 ALA ALA E . n +E 1 149 ASP 149 149 149 ASP ASP E . n +E 1 150 THR 150 150 150 THR THR E . n +E 1 151 GLN 151 151 151 GLN GLN E . n +E 1 152 TYR 152 152 152 TYR TYR E . n +E 1 153 GLN 153 153 153 GLN GLN E . n +E 1 154 LEU 154 154 154 LEU LEU E . n +E 1 155 ASP 155 155 155 ASP ASP E . n +E 1 156 GLN 156 156 156 GLN GLN E . n +E 1 157 ILE 157 157 157 ILE ILE E . n +E 1 158 ALA 158 158 158 ALA ALA E . n +E 1 159 VAL 159 159 159 VAL VAL E . n +E 1 160 ASN 160 160 160 ASN ASN E . n +E 1 161 LEU 161 161 161 LEU LEU E . n +E 1 162 ARG 162 162 162 ARG ARG E . n +E 1 163 VAL 163 163 163 VAL VAL E . n +E 1 164 VAL 164 164 164 VAL VAL E . n +E 1 165 ASN 165 165 165 ASN ASN E . n +E 1 166 VAL 166 166 166 VAL VAL E . n +E 1 167 SER 167 167 167 SER SER E . n +E 1 168 THR 168 168 168 THR THR E . n +E 1 169 GLY 169 169 169 GLY GLY E . n +E 1 170 GLU 170 170 170 GLU GLU E . n +E 1 171 ILE 171 171 171 ILE ILE E . n +E 1 172 LEU 172 172 172 LEU LEU E . n +E 1 173 SER 173 173 173 SER SER E . n +E 1 174 SER 174 174 174 SER SER E . n +E 1 175 VAL 175 175 175 VAL VAL E . n +E 1 176 ASN 176 176 176 ASN ASN E . n +E 1 177 THR 177 177 177 THR THR E . n +E 1 178 SER 178 178 178 SER SER E . n +E 1 179 LYS 179 179 179 LYS LYS E . n +E 1 180 THR 180 180 180 THR THR E . n +E 1 181 ILE 181 181 181 ILE ILE E . n +E 1 182 LEU 182 182 182 LEU LEU E . n +E 1 183 SER 183 183 183 SER SER E . n +E 1 184 TYR 184 184 184 TYR TYR E . n +E 1 185 GLU 185 185 185 GLU GLU E . n +E 1 186 VAL 186 186 186 VAL VAL E . n +E 1 187 GLN 187 187 187 GLN GLN E . n +E 1 188 ALA 188 188 188 ALA ALA E . n +E 1 189 GLY 189 189 189 GLY GLY E . n +E 1 190 VAL 190 190 190 VAL VAL E . n +E 1 191 PHE 191 191 191 PHE PHE E . n +E 1 192 ARG 192 192 ? ? ? E . n +E 1 193 PHE 193 193 ? ? ? E . n +E 1 194 ILE 194 194 ? ? ? E . n +E 1 195 ASP 195 195 ? ? ? E . n +E 1 196 TYR 196 196 ? ? ? E . n +E 1 197 GLN 197 197 ? ? ? E . n +E 1 198 ARG 198 198 ? ? ? E . n +E 1 199 LEU 199 199 ? ? ? E . n +E 1 200 LEU 200 200 200 LEU LEU E . n +E 1 201 GLU 201 201 201 GLU GLU E . n +E 1 202 GLY 202 202 202 GLY GLY E . n +E 1 203 GLU 203 203 203 GLU GLU E . n +E 1 204 VAL 204 204 204 VAL VAL E . n +E 1 205 GLY 205 205 205 GLY GLY E . n +E 1 206 TYR 206 206 206 TYR TYR E . n +E 1 207 THR 207 207 207 THR THR E . n +E 1 208 SER 208 208 208 SER SER E . n +E 1 209 ASN 209 209 209 ASN ASN E . n +E 1 210 GLU 210 210 210 GLU GLU E . n +E 1 211 PRO 211 211 211 PRO PRO E . n +E 1 212 VAL 212 212 212 VAL VAL E . n +E 1 213 MET 213 213 213 MET MET E . n +E 1 214 LEU 214 214 214 LEU LEU E . n +E 1 215 CYS 215 215 215 CYS CYS E . n +E 1 216 LEU 216 216 216 LEU LEU E . n +E 1 217 MET 217 217 217 MET MET E . n +E 1 218 SER 218 218 218 SER SER E . n +E 1 219 ALA 219 219 219 ALA ALA E . n +E 1 220 ILE 220 220 220 ILE ILE E . n +E 1 221 GLU 221 221 221 GLU GLU E . n +E 1 222 THR 222 222 222 THR THR E . n +E 1 223 GLY 223 223 223 GLY GLY E . n +E 1 224 VAL 224 224 224 VAL VAL E . n +E 1 225 ILE 225 225 225 ILE ILE E . n +E 1 226 PHE 226 226 226 PHE PHE E . n +E 1 227 LEU 227 227 227 LEU LEU E . n +E 1 228 ILE 228 228 228 ILE ILE E . n +E 1 229 ASN 229 229 229 ASN ASN E . n +E 1 230 ASP 230 230 230 ASP ASP E . n +E 1 231 GLY 231 231 231 GLY GLY E . n +E 1 232 ILE 232 232 232 ILE ILE E . n +E 1 233 ASP 233 233 233 ASP ASP E . n +E 1 234 ARG 234 234 234 ARG ARG E . n +E 1 235 GLY 235 235 235 GLY GLY E . n +E 1 236 LEU 236 236 236 LEU LEU E . n +E 1 237 TRP 237 237 237 TRP TRP E . n +E 1 238 ASP 238 238 238 ASP ASP E . n +E 1 239 LEU 239 239 239 LEU LEU E . n +E 1 240 GLN 240 240 240 GLN GLN E . n +E 1 241 ASN 241 241 241 ASN ASN E . n +E 1 242 LYS 242 242 242 LYS LYS E . n +E 1 243 ALA 243 243 243 ALA ALA E . n +E 1 244 GLU 244 244 244 GLU GLU E . n +E 1 245 ARG 245 245 245 ARG ARG E . n +E 1 246 GLN 246 246 246 GLN GLN E . n +E 1 247 ASN 247 247 247 ASN ASN E . n +E 1 248 ASP 248 248 248 ASP ASP E . n +E 1 249 ILE 249 249 249 ILE ILE E . n +E 1 250 LEU 250 250 250 LEU LEU E . n +E 1 251 VAL 251 251 251 VAL VAL E . n +E 1 252 LYS 252 252 252 LYS LYS E . n +E 1 253 TYR 253 253 253 TYR TYR E . n +E 1 254 ARG 254 254 254 ARG ARG E . n +E 1 255 HIS 255 255 255 HIS HIS E . n +E 1 256 MET 256 256 256 MET MET E . n +E 1 257 SER 257 257 257 SER SER E . n +E 1 258 VAL 258 258 ? ? ? E . n +E 1 259 PRO 259 259 ? ? ? E . n +E 1 260 PRO 260 260 ? ? ? E . n +E 1 261 GLU 261 261 ? ? ? E . n +E 1 262 SER 262 262 ? ? ? E . n +F 1 1 CYS 1 1 ? ? ? F . n +F 1 2 LEU 2 2 2 LEU LEU F . n +F 1 3 THR 3 3 3 THR THR F . n +F 1 4 ALA 4 4 4 ALA ALA F . n +F 1 5 PRO 5 5 5 PRO PRO F . n +F 1 6 PRO 6 6 6 PRO PRO F . n +F 1 7 LYS 7 7 7 LYS LYS F . n +F 1 8 GLU 8 8 8 GLU GLU F . n +F 1 9 ALA 9 9 9 ALA ALA F . n +F 1 10 ALA 10 10 10 ALA ALA F . n +F 1 11 ARG 11 11 11 ARG ARG F . n +F 1 12 PRO 12 12 12 PRO PRO F . n +F 1 13 THR 13 13 13 THR THR F . n +F 1 14 LEU 14 14 14 LEU LEU F . n +F 1 15 MET 15 15 15 MET MET F . n +F 1 16 PRO 16 16 16 PRO PRO F . n +F 1 17 ARG 17 17 17 ARG ARG F . n +F 1 18 ALA 18 18 18 ALA ALA F . n +F 1 19 GLN 19 19 19 GLN GLN F . n +F 1 20 SER 20 20 20 SER SER F . n +F 1 21 TYR 21 21 21 TYR TYR F . n +F 1 22 LYS 22 22 22 LYS LYS F . n +F 1 23 ASP 23 23 23 ASP ASP F . n +F 1 24 LEU 24 24 24 LEU LEU F . n +F 1 25 THR 25 25 25 THR THR F . n +F 1 26 HIS 26 26 26 HIS HIS F . n +F 1 27 LEU 27 27 27 LEU LEU F . n +F 1 28 PRO 28 28 28 PRO PRO F . n +F 1 29 ALA 29 29 29 ALA ALA F . n +F 1 30 PRO 30 30 30 PRO PRO F . n +F 1 31 THR 31 31 31 THR THR F . n +F 1 32 GLY 32 32 32 GLY GLY F . n +F 1 33 LYS 33 33 33 LYS LYS F . n +F 1 34 ILE 34 34 34 ILE ILE F . n +F 1 35 PHE 35 35 35 PHE PHE F . n +F 1 36 VAL 36 36 36 VAL VAL F . n +F 1 37 SER 37 37 37 SER SER F . n +F 1 38 VAL 38 38 38 VAL VAL F . n +F 1 39 TYR 39 39 39 TYR TYR F . n +F 1 40 ASN 40 40 40 ASN ASN F . n +F 1 41 ILE 41 41 41 ILE ILE F . n +F 1 42 GLN 42 42 42 GLN GLN F . n +F 1 43 ASP 43 43 43 ASP ASP F . n +F 1 44 GLU 44 44 44 GLU GLU F . n +F 1 45 THR 45 45 45 THR THR F . n +F 1 46 GLY 46 46 46 GLY GLY F . n +F 1 47 GLN 47 47 47 GLN GLN F . n +F 1 48 PHE 48 48 48 PHE PHE F . n +F 1 49 LYS 49 49 49 LYS LYS F . n +F 1 50 PRO 50 50 50 PRO PRO F . n +F 1 51 TYR 51 51 51 TYR TYR F . n +F 1 52 PRO 52 52 52 PRO PRO F . n +F 1 53 ALA 53 53 53 ALA ALA F . n +F 1 54 SER 54 54 54 SER SER F . n +F 1 55 ASN 55 55 55 ASN ASN F . n +F 1 56 PHE 56 56 56 PHE PHE F . n +F 1 57 SER 57 57 57 SER SER F . n +F 1 58 THR 58 58 58 THR THR F . n +F 1 59 ALA 59 59 59 ALA ALA F . n +F 1 60 VAL 60 60 60 VAL VAL F . n +F 1 61 PRO 61 61 61 PRO PRO F . n +F 1 62 GLN 62 62 62 GLN GLN F . n +F 1 63 SER 63 63 63 SER SER F . n +F 1 64 ALA 64 64 64 ALA ALA F . n +F 1 65 THR 65 65 65 THR THR F . n +F 1 66 ALA 66 66 66 ALA ALA F . n +F 1 67 MET 67 67 67 MET MET F . n +F 1 68 LEU 68 68 68 LEU LEU F . n +F 1 69 VAL 69 69 69 VAL VAL F . n +F 1 70 THR 70 70 70 THR THR F . n +F 1 71 ALA 71 71 71 ALA ALA F . n +F 1 72 LEU 72 72 72 LEU LEU F . n +F 1 73 LYS 73 73 73 LYS LYS F . n +F 1 74 ASP 74 74 74 ASP ASP F . n +F 1 75 SER 75 75 75 SER SER F . n +F 1 76 ARG 76 76 76 ARG ARG F . n +F 1 77 TRP 77 77 77 TRP TRP F . n +F 1 78 PHE 78 78 78 PHE PHE F . n +F 1 79 ILE 79 79 79 ILE ILE F . n +F 1 80 PRO 80 80 80 PRO PRO F . n +F 1 81 LEU 81 81 81 LEU LEU F . n +F 1 82 GLU 82 82 82 GLU GLU F . n +F 1 83 ARG 83 83 83 ARG ARG F . n +F 1 84 GLN 84 84 84 GLN GLN F . n +F 1 85 GLY 85 85 85 GLY GLY F . n +F 1 86 LEU 86 86 86 LEU LEU F . n +F 1 87 GLN 87 87 87 GLN GLN F . n +F 1 88 ASN 88 88 88 ASN ASN F . n +F 1 89 LEU 89 89 89 LEU LEU F . n +F 1 90 LEU 90 90 90 LEU LEU F . n +F 1 91 ASN 91 91 91 ASN ASN F . n +F 1 92 GLU 92 92 92 GLU GLU F . n +F 1 93 ARG 93 93 93 ARG ARG F . n +F 1 94 LYS 94 94 94 LYS LYS F . n +F 1 95 ILE 95 95 95 ILE ILE F . n +F 1 96 ILE 96 96 96 ILE ILE F . n +F 1 97 ARG 97 97 97 ARG ARG F . n +F 1 98 ALA 98 98 98 ALA ALA F . n +F 1 99 ALA 99 99 99 ALA ALA F . n +F 1 100 GLN 100 100 100 GLN GLN F . n +F 1 101 GLU 101 101 101 GLU GLU F . n +F 1 102 ASN 102 102 102 ASN ASN F . n +F 1 103 GLY 103 103 103 GLY GLY F . n +F 1 104 THR 104 104 104 THR THR F . n +F 1 105 VAL 105 105 105 VAL VAL F . n +F 1 106 ALA 106 106 106 ALA ALA F . n +F 1 107 ILE 107 107 107 ILE ILE F . n +F 1 108 ASN 108 108 108 ASN ASN F . n +F 1 109 ASN 109 109 109 ASN ASN F . n +F 1 110 ARG 110 110 110 ARG ARG F . n +F 1 111 ILE 111 111 111 ILE ILE F . n +F 1 112 PRO 112 112 112 PRO PRO F . n +F 1 113 LEU 113 113 113 LEU LEU F . n +F 1 114 GLN 114 114 114 GLN GLN F . n +F 1 115 SER 115 115 115 SER SER F . n +F 1 116 LEU 116 116 116 LEU LEU F . n +F 1 117 THR 117 117 117 THR THR F . n +F 1 118 ALA 118 118 118 ALA ALA F . n +F 1 119 ALA 119 119 119 ALA ALA F . n +F 1 120 ASN 120 120 120 ASN ASN F . n +F 1 121 ILE 121 121 121 ILE ILE F . n +F 1 122 MET 122 122 122 MET MET F . n +F 1 123 VAL 123 123 123 VAL VAL F . n +F 1 124 GLU 124 124 124 GLU GLU F . n +F 1 125 GLY 125 125 125 GLY GLY F . n +F 1 126 SER 126 126 126 SER SER F . n +F 1 127 ILE 127 127 127 ILE ILE F . n +F 1 128 ILE 128 128 128 ILE ILE F . n +F 1 129 GLY 129 129 129 GLY GLY F . n +F 1 130 TYR 130 130 130 TYR TYR F . n +F 1 131 GLU 131 131 131 GLU GLU F . n +F 1 132 SER 132 132 132 SER SER F . n +F 1 133 ASN 133 133 133 ASN ASN F . n +F 1 134 VAL 134 134 134 VAL VAL F . n +F 1 135 LYS 135 135 135 LYS LYS F . n +F 1 136 SER 136 136 136 SER SER F . n +F 1 137 GLY 137 137 137 GLY GLY F . n +F 1 138 GLY 138 138 138 GLY GLY F . n +F 1 139 VAL 139 139 139 VAL VAL F . n +F 1 140 GLY 140 140 140 GLY GLY F . n +F 1 141 ALA 141 141 141 ALA ALA F . n +F 1 142 ARG 142 142 142 ARG ARG F . n +F 1 143 TYR 143 143 143 TYR TYR F . n +F 1 144 PHE 144 144 ? ? ? F . n +F 1 145 GLY 145 145 145 GLY GLY F . n +F 1 146 ILE 146 146 146 ILE ILE F . n +F 1 147 GLY 147 147 147 GLY GLY F . n +F 1 148 ALA 148 148 148 ALA ALA F . n +F 1 149 ASP 149 149 149 ASP ASP F . n +F 1 150 THR 150 150 150 THR THR F . n +F 1 151 GLN 151 151 151 GLN GLN F . n +F 1 152 TYR 152 152 152 TYR TYR F . n +F 1 153 GLN 153 153 153 GLN GLN F . n +F 1 154 LEU 154 154 154 LEU LEU F . n +F 1 155 ASP 155 155 155 ASP ASP F . n +F 1 156 GLN 156 156 156 GLN GLN F . n +F 1 157 ILE 157 157 157 ILE ILE F . n +F 1 158 ALA 158 158 158 ALA ALA F . n +F 1 159 VAL 159 159 159 VAL VAL F . n +F 1 160 ASN 160 160 160 ASN ASN F . n +F 1 161 LEU 161 161 161 LEU LEU F . n +F 1 162 ARG 162 162 162 ARG ARG F . n +F 1 163 VAL 163 163 163 VAL VAL F . n +F 1 164 VAL 164 164 164 VAL VAL F . n +F 1 165 ASN 165 165 165 ASN ASN F . n +F 1 166 VAL 166 166 166 VAL VAL F . n +F 1 167 SER 167 167 167 SER SER F . n +F 1 168 THR 168 168 168 THR THR F . n +F 1 169 GLY 169 169 169 GLY GLY F . n +F 1 170 GLU 170 170 170 GLU GLU F . n +F 1 171 ILE 171 171 171 ILE ILE F . n +F 1 172 LEU 172 172 172 LEU LEU F . n +F 1 173 SER 173 173 173 SER SER F . n +F 1 174 SER 174 174 174 SER SER F . n +F 1 175 VAL 175 175 175 VAL VAL F . n +F 1 176 ASN 176 176 176 ASN ASN F . n +F 1 177 THR 177 177 177 THR THR F . n +F 1 178 SER 178 178 178 SER SER F . n +F 1 179 LYS 179 179 179 LYS LYS F . n +F 1 180 THR 180 180 180 THR THR F . n +F 1 181 ILE 181 181 181 ILE ILE F . n +F 1 182 LEU 182 182 182 LEU LEU F . n +F 1 183 SER 183 183 183 SER SER F . n +F 1 184 TYR 184 184 184 TYR TYR F . n +F 1 185 GLU 185 185 185 GLU GLU F . n +F 1 186 VAL 186 186 186 VAL VAL F . n +F 1 187 GLN 187 187 187 GLN GLN F . n +F 1 188 ALA 188 188 188 ALA ALA F . n +F 1 189 GLY 189 189 189 GLY GLY F . n +F 1 190 VAL 190 190 190 VAL VAL F . n +F 1 191 PHE 191 191 191 PHE PHE F . n +F 1 192 ARG 192 192 ? ? ? F . n +F 1 193 PHE 193 193 ? ? ? F . n +F 1 194 ILE 194 194 ? ? ? F . n +F 1 195 ASP 195 195 ? ? ? F . n +F 1 196 TYR 196 196 ? ? ? F . n +F 1 197 GLN 197 197 ? ? ? F . n +F 1 198 ARG 198 198 ? ? ? F . n +F 1 199 LEU 199 199 ? ? ? F . n +F 1 200 LEU 200 200 200 LEU LEU F . n +F 1 201 GLU 201 201 201 GLU GLU F . n +F 1 202 GLY 202 202 202 GLY GLY F . n +F 1 203 GLU 203 203 203 GLU GLU F . n +F 1 204 VAL 204 204 204 VAL VAL F . n +F 1 205 GLY 205 205 205 GLY GLY F . n +F 1 206 TYR 206 206 206 TYR TYR F . n +F 1 207 THR 207 207 207 THR THR F . n +F 1 208 SER 208 208 208 SER SER F . n +F 1 209 ASN 209 209 209 ASN ASN F . n +F 1 210 GLU 210 210 210 GLU GLU F . n +F 1 211 PRO 211 211 211 PRO PRO F . n +F 1 212 VAL 212 212 212 VAL VAL F . n +F 1 213 MET 213 213 213 MET MET F . n +F 1 214 LEU 214 214 214 LEU LEU F . n +F 1 215 CYS 215 215 215 CYS CYS F . n +F 1 216 LEU 216 216 216 LEU LEU F . n +F 1 217 MET 217 217 217 MET MET F . n +F 1 218 SER 218 218 218 SER SER F . n +F 1 219 ALA 219 219 219 ALA ALA F . n +F 1 220 ILE 220 220 220 ILE ILE F . n +F 1 221 GLU 221 221 221 GLU GLU F . n +F 1 222 THR 222 222 222 THR THR F . n +F 1 223 GLY 223 223 223 GLY GLY F . n +F 1 224 VAL 224 224 224 VAL VAL F . n +F 1 225 ILE 225 225 225 ILE ILE F . n +F 1 226 PHE 226 226 226 PHE PHE F . n +F 1 227 LEU 227 227 227 LEU LEU F . n +F 1 228 ILE 228 228 228 ILE ILE F . n +F 1 229 ASN 229 229 229 ASN ASN F . n +F 1 230 ASP 230 230 230 ASP ASP F . n +F 1 231 GLY 231 231 231 GLY GLY F . n +F 1 232 ILE 232 232 232 ILE ILE F . n +F 1 233 ASP 233 233 233 ASP ASP F . n +F 1 234 ARG 234 234 234 ARG ARG F . n +F 1 235 GLY 235 235 235 GLY GLY F . n +F 1 236 LEU 236 236 236 LEU LEU F . n +F 1 237 TRP 237 237 237 TRP TRP F . n +F 1 238 ASP 238 238 238 ASP ASP F . n +F 1 239 LEU 239 239 239 LEU LEU F . n +F 1 240 GLN 240 240 240 GLN GLN F . n +F 1 241 ASN 241 241 241 ASN ASN F . n +F 1 242 LYS 242 242 242 LYS LYS F . n +F 1 243 ALA 243 243 243 ALA ALA F . n +F 1 244 GLU 244 244 244 GLU GLU F . n +F 1 245 ARG 245 245 245 ARG ARG F . n +F 1 246 GLN 246 246 246 GLN GLN F . n +F 1 247 ASN 247 247 247 ASN ASN F . n +F 1 248 ASP 248 248 248 ASP ASP F . n +F 1 249 ILE 249 249 249 ILE ILE F . n +F 1 250 LEU 250 250 250 LEU LEU F . n +F 1 251 VAL 251 251 251 VAL VAL F . n +F 1 252 LYS 252 252 252 LYS LYS F . n +F 1 253 TYR 253 253 253 TYR TYR F . n +F 1 254 ARG 254 254 254 ARG ARG F . n +F 1 255 HIS 255 255 255 HIS HIS F . n +F 1 256 MET 256 256 256 MET MET F . n +F 1 257 SER 257 257 257 SER SER F . n +F 1 258 VAL 258 258 ? ? ? F . n +F 1 259 PRO 259 259 ? ? ? F . n +F 1 260 PRO 260 260 ? ? ? F . n +F 1 261 GLU 261 261 ? ? ? F . n +F 1 262 SER 262 262 ? ? ? F . n +G 1 1 CYS 1 1 ? ? ? G . n +G 1 2 LEU 2 2 2 LEU LEU G . n +G 1 3 THR 3 3 3 THR THR G . n +G 1 4 ALA 4 4 4 ALA ALA G . n +G 1 5 PRO 5 5 5 PRO PRO G . n +G 1 6 PRO 6 6 6 PRO PRO G . n +G 1 7 LYS 7 7 7 LYS LYS G . n +G 1 8 GLU 8 8 8 GLU GLU G . n +G 1 9 ALA 9 9 9 ALA ALA G . n +G 1 10 ALA 10 10 10 ALA ALA G . n +G 1 11 ARG 11 11 11 ARG ARG G . n +G 1 12 PRO 12 12 12 PRO PRO G . n +G 1 13 THR 13 13 13 THR THR G . n +G 1 14 LEU 14 14 14 LEU LEU G . n +G 1 15 MET 15 15 15 MET MET G . n +G 1 16 PRO 16 16 16 PRO PRO G . n +G 1 17 ARG 17 17 17 ARG ARG G . n +G 1 18 ALA 18 18 18 ALA ALA G . n +G 1 19 GLN 19 19 19 GLN GLN G . n +G 1 20 SER 20 20 20 SER SER G . n +G 1 21 TYR 21 21 21 TYR TYR G . n +G 1 22 LYS 22 22 22 LYS LYS G . n +G 1 23 ASP 23 23 23 ASP ASP G . n +G 1 24 LEU 24 24 24 LEU LEU G . n +G 1 25 THR 25 25 25 THR THR G . n +G 1 26 HIS 26 26 26 HIS HIS G . n +G 1 27 LEU 27 27 27 LEU LEU G . n +G 1 28 PRO 28 28 28 PRO PRO G . n +G 1 29 ALA 29 29 29 ALA ALA G . n +G 1 30 PRO 30 30 30 PRO PRO G . n +G 1 31 THR 31 31 31 THR THR G . n +G 1 32 GLY 32 32 32 GLY GLY G . n +G 1 33 LYS 33 33 33 LYS LYS G . n +G 1 34 ILE 34 34 34 ILE ILE G . n +G 1 35 PHE 35 35 35 PHE PHE G . n +G 1 36 VAL 36 36 36 VAL VAL G . n +G 1 37 SER 37 37 37 SER SER G . n +G 1 38 VAL 38 38 38 VAL VAL G . n +G 1 39 TYR 39 39 39 TYR TYR G . n +G 1 40 ASN 40 40 40 ASN ASN G . n +G 1 41 ILE 41 41 41 ILE ILE G . n +G 1 42 GLN 42 42 42 GLN GLN G . n +G 1 43 ASP 43 43 43 ASP ASP G . n +G 1 44 GLU 44 44 44 GLU GLU G . n +G 1 45 THR 45 45 45 THR THR G . n +G 1 46 GLY 46 46 46 GLY GLY G . n +G 1 47 GLN 47 47 47 GLN GLN G . n +G 1 48 PHE 48 48 48 PHE PHE G . n +G 1 49 LYS 49 49 49 LYS LYS G . n +G 1 50 PRO 50 50 50 PRO PRO G . n +G 1 51 TYR 51 51 51 TYR TYR G . n +G 1 52 PRO 52 52 52 PRO PRO G . n +G 1 53 ALA 53 53 53 ALA ALA G . n +G 1 54 SER 54 54 54 SER SER G . n +G 1 55 ASN 55 55 55 ASN ASN G . n +G 1 56 PHE 56 56 56 PHE PHE G . n +G 1 57 SER 57 57 57 SER SER G . n +G 1 58 THR 58 58 58 THR THR G . n +G 1 59 ALA 59 59 59 ALA ALA G . n +G 1 60 VAL 60 60 60 VAL VAL G . n +G 1 61 PRO 61 61 61 PRO PRO G . n +G 1 62 GLN 62 62 62 GLN GLN G . n +G 1 63 SER 63 63 63 SER SER G . n +G 1 64 ALA 64 64 64 ALA ALA G . n +G 1 65 THR 65 65 65 THR THR G . n +G 1 66 ALA 66 66 66 ALA ALA G . n +G 1 67 MET 67 67 67 MET MET G . n +G 1 68 LEU 68 68 68 LEU LEU G . n +G 1 69 VAL 69 69 69 VAL VAL G . n +G 1 70 THR 70 70 70 THR THR G . n +G 1 71 ALA 71 71 71 ALA ALA G . n +G 1 72 LEU 72 72 72 LEU LEU G . n +G 1 73 LYS 73 73 73 LYS LYS G . n +G 1 74 ASP 74 74 74 ASP ASP G . n +G 1 75 SER 75 75 75 SER SER G . n +G 1 76 ARG 76 76 76 ARG ARG G . n +G 1 77 TRP 77 77 77 TRP TRP G . n +G 1 78 PHE 78 78 78 PHE PHE G . n +G 1 79 ILE 79 79 79 ILE ILE G . n +G 1 80 PRO 80 80 80 PRO PRO G . n +G 1 81 LEU 81 81 81 LEU LEU G . n +G 1 82 GLU 82 82 82 GLU GLU G . n +G 1 83 ARG 83 83 83 ARG ARG G . n +G 1 84 GLN 84 84 84 GLN GLN G . n +G 1 85 GLY 85 85 85 GLY GLY G . n +G 1 86 LEU 86 86 86 LEU LEU G . n +G 1 87 GLN 87 87 87 GLN GLN G . n +G 1 88 ASN 88 88 88 ASN ASN G . n +G 1 89 LEU 89 89 89 LEU LEU G . n +G 1 90 LEU 90 90 90 LEU LEU G . n +G 1 91 ASN 91 91 91 ASN ASN G . n +G 1 92 GLU 92 92 92 GLU GLU G . n +G 1 93 ARG 93 93 93 ARG ARG G . n +G 1 94 LYS 94 94 94 LYS LYS G . n +G 1 95 ILE 95 95 95 ILE ILE G . n +G 1 96 ILE 96 96 96 ILE ILE G . n +G 1 97 ARG 97 97 97 ARG ARG G . n +G 1 98 ALA 98 98 98 ALA ALA G . n +G 1 99 ALA 99 99 99 ALA ALA G . n +G 1 100 GLN 100 100 100 GLN GLN G . n +G 1 101 GLU 101 101 101 GLU GLU G . n +G 1 102 ASN 102 102 102 ASN ASN G . n +G 1 103 GLY 103 103 103 GLY GLY G . n +G 1 104 THR 104 104 104 THR THR G . n +G 1 105 VAL 105 105 105 VAL VAL G . n +G 1 106 ALA 106 106 106 ALA ALA G . n +G 1 107 ILE 107 107 107 ILE ILE G . n +G 1 108 ASN 108 108 108 ASN ASN G . n +G 1 109 ASN 109 109 109 ASN ASN G . n +G 1 110 ARG 110 110 110 ARG ARG G . n +G 1 111 ILE 111 111 111 ILE ILE G . n +G 1 112 PRO 112 112 112 PRO PRO G . n +G 1 113 LEU 113 113 113 LEU LEU G . n +G 1 114 GLN 114 114 114 GLN GLN G . n +G 1 115 SER 115 115 115 SER SER G . n +G 1 116 LEU 116 116 116 LEU LEU G . n +G 1 117 THR 117 117 117 THR THR G . n +G 1 118 ALA 118 118 118 ALA ALA G . n +G 1 119 ALA 119 119 119 ALA ALA G . n +G 1 120 ASN 120 120 120 ASN ASN G . n +G 1 121 ILE 121 121 121 ILE ILE G . n +G 1 122 MET 122 122 122 MET MET G . n +G 1 123 VAL 123 123 123 VAL VAL G . n +G 1 124 GLU 124 124 124 GLU GLU G . n +G 1 125 GLY 125 125 125 GLY GLY G . n +G 1 126 SER 126 126 126 SER SER G . n +G 1 127 ILE 127 127 127 ILE ILE G . n +G 1 128 ILE 128 128 128 ILE ILE G . n +G 1 129 GLY 129 129 129 GLY GLY G . n +G 1 130 TYR 130 130 130 TYR TYR G . n +G 1 131 GLU 131 131 131 GLU GLU G . n +G 1 132 SER 132 132 132 SER SER G . n +G 1 133 ASN 133 133 133 ASN ASN G . n +G 1 134 VAL 134 134 134 VAL VAL G . n +G 1 135 LYS 135 135 135 LYS LYS G . n +G 1 136 SER 136 136 136 SER SER G . n +G 1 137 GLY 137 137 137 GLY GLY G . n +G 1 138 GLY 138 138 138 GLY GLY G . n +G 1 139 VAL 139 139 139 VAL VAL G . n +G 1 140 GLY 140 140 140 GLY GLY G . n +G 1 141 ALA 141 141 141 ALA ALA G . n +G 1 142 ARG 142 142 142 ARG ARG G . n +G 1 143 TYR 143 143 143 TYR TYR G . n +G 1 144 PHE 144 144 ? ? ? G . n +G 1 145 GLY 145 145 145 GLY GLY G . n +G 1 146 ILE 146 146 146 ILE ILE G . n +G 1 147 GLY 147 147 147 GLY GLY G . n +G 1 148 ALA 148 148 148 ALA ALA G . n +G 1 149 ASP 149 149 149 ASP ASP G . n +G 1 150 THR 150 150 150 THR THR G . n +G 1 151 GLN 151 151 151 GLN GLN G . n +G 1 152 TYR 152 152 152 TYR TYR G . n +G 1 153 GLN 153 153 153 GLN GLN G . n +G 1 154 LEU 154 154 154 LEU LEU G . n +G 1 155 ASP 155 155 155 ASP ASP G . n +G 1 156 GLN 156 156 156 GLN GLN G . n +G 1 157 ILE 157 157 157 ILE ILE G . n +G 1 158 ALA 158 158 158 ALA ALA G . n +G 1 159 VAL 159 159 159 VAL VAL G . n +G 1 160 ASN 160 160 160 ASN ASN G . n +G 1 161 LEU 161 161 161 LEU LEU G . n +G 1 162 ARG 162 162 162 ARG ARG G . n +G 1 163 VAL 163 163 163 VAL VAL G . n +G 1 164 VAL 164 164 164 VAL VAL G . n +G 1 165 ASN 165 165 165 ASN ASN G . n +G 1 166 VAL 166 166 166 VAL VAL G . n +G 1 167 SER 167 167 167 SER SER G . n +G 1 168 THR 168 168 168 THR THR G . n +G 1 169 GLY 169 169 169 GLY GLY G . n +G 1 170 GLU 170 170 170 GLU GLU G . n +G 1 171 ILE 171 171 171 ILE ILE G . n +G 1 172 LEU 172 172 172 LEU LEU G . n +G 1 173 SER 173 173 173 SER SER G . n +G 1 174 SER 174 174 174 SER SER G . n +G 1 175 VAL 175 175 175 VAL VAL G . n +G 1 176 ASN 176 176 176 ASN ASN G . n +G 1 177 THR 177 177 177 THR THR G . n +G 1 178 SER 178 178 178 SER SER G . n +G 1 179 LYS 179 179 179 LYS LYS G . n +G 1 180 THR 180 180 180 THR THR G . n +G 1 181 ILE 181 181 181 ILE ILE G . n +G 1 182 LEU 182 182 182 LEU LEU G . n +G 1 183 SER 183 183 183 SER SER G . n +G 1 184 TYR 184 184 184 TYR TYR G . n +G 1 185 GLU 185 185 185 GLU GLU G . n +G 1 186 VAL 186 186 186 VAL VAL G . n +G 1 187 GLN 187 187 187 GLN GLN G . n +G 1 188 ALA 188 188 188 ALA ALA G . n +G 1 189 GLY 189 189 189 GLY GLY G . n +G 1 190 VAL 190 190 190 VAL VAL G . n +G 1 191 PHE 191 191 191 PHE PHE G . n +G 1 192 ARG 192 192 ? ? ? G . n +G 1 193 PHE 193 193 ? ? ? G . n +G 1 194 ILE 194 194 ? ? ? G . n +G 1 195 ASP 195 195 ? ? ? G . n +G 1 196 TYR 196 196 ? ? ? G . n +G 1 197 GLN 197 197 ? ? ? G . n +G 1 198 ARG 198 198 ? ? ? G . n +G 1 199 LEU 199 199 ? ? ? G . n +G 1 200 LEU 200 200 200 LEU LEU G . n +G 1 201 GLU 201 201 201 GLU GLU G . n +G 1 202 GLY 202 202 202 GLY GLY G . n +G 1 203 GLU 203 203 203 GLU GLU G . n +G 1 204 VAL 204 204 204 VAL VAL G . n +G 1 205 GLY 205 205 205 GLY GLY G . n +G 1 206 TYR 206 206 206 TYR TYR G . n +G 1 207 THR 207 207 207 THR THR G . n +G 1 208 SER 208 208 208 SER SER G . n +G 1 209 ASN 209 209 209 ASN ASN G . n +G 1 210 GLU 210 210 210 GLU GLU G . n +G 1 211 PRO 211 211 211 PRO PRO G . n +G 1 212 VAL 212 212 212 VAL VAL G . n +G 1 213 MET 213 213 213 MET MET G . n +G 1 214 LEU 214 214 214 LEU LEU G . n +G 1 215 CYS 215 215 215 CYS CYS G . n +G 1 216 LEU 216 216 216 LEU LEU G . n +G 1 217 MET 217 217 217 MET MET G . n +G 1 218 SER 218 218 218 SER SER G . n +G 1 219 ALA 219 219 219 ALA ALA G . n +G 1 220 ILE 220 220 220 ILE ILE G . n +G 1 221 GLU 221 221 221 GLU GLU G . n +G 1 222 THR 222 222 222 THR THR G . n +G 1 223 GLY 223 223 223 GLY GLY G . n +G 1 224 VAL 224 224 224 VAL VAL G . n +G 1 225 ILE 225 225 225 ILE ILE G . n +G 1 226 PHE 226 226 226 PHE PHE G . n +G 1 227 LEU 227 227 227 LEU LEU G . n +G 1 228 ILE 228 228 228 ILE ILE G . n +G 1 229 ASN 229 229 229 ASN ASN G . n +G 1 230 ASP 230 230 230 ASP ASP G . n +G 1 231 GLY 231 231 231 GLY GLY G . n +G 1 232 ILE 232 232 232 ILE ILE G . n +G 1 233 ASP 233 233 233 ASP ASP G . n +G 1 234 ARG 234 234 234 ARG ARG G . n +G 1 235 GLY 235 235 235 GLY GLY G . n +G 1 236 LEU 236 236 236 LEU LEU G . n +G 1 237 TRP 237 237 237 TRP TRP G . n +G 1 238 ASP 238 238 238 ASP ASP G . n +G 1 239 LEU 239 239 239 LEU LEU G . n +G 1 240 GLN 240 240 240 GLN GLN G . n +G 1 241 ASN 241 241 241 ASN ASN G . n +G 1 242 LYS 242 242 242 LYS LYS G . n +G 1 243 ALA 243 243 243 ALA ALA G . n +G 1 244 GLU 244 244 244 GLU GLU G . n +G 1 245 ARG 245 245 245 ARG ARG G . n +G 1 246 GLN 246 246 246 GLN GLN G . n +G 1 247 ASN 247 247 247 ASN ASN G . n +G 1 248 ASP 248 248 248 ASP ASP G . n +G 1 249 ILE 249 249 249 ILE ILE G . n +G 1 250 LEU 250 250 250 LEU LEU G . n +G 1 251 VAL 251 251 251 VAL VAL G . n +G 1 252 LYS 252 252 252 LYS LYS G . n +G 1 253 TYR 253 253 253 TYR TYR G . n +G 1 254 ARG 254 254 254 ARG ARG G . n +G 1 255 HIS 255 255 255 HIS HIS G . n +G 1 256 MET 256 256 256 MET MET G . n +G 1 257 SER 257 257 257 SER SER G . n +G 1 258 VAL 258 258 ? ? ? G . n +G 1 259 PRO 259 259 ? ? ? G . n +G 1 260 PRO 260 260 ? ? ? G . n +G 1 261 GLU 261 261 ? ? ? G . n +G 1 262 SER 262 262 ? ? ? G . n +H 1 1 CYS 1 1 ? ? ? H . n +H 1 2 LEU 2 2 2 LEU LEU H . n +H 1 3 THR 3 3 3 THR THR H . n +H 1 4 ALA 4 4 4 ALA ALA H . n +H 1 5 PRO 5 5 5 PRO PRO H . n +H 1 6 PRO 6 6 6 PRO PRO H . n +H 1 7 LYS 7 7 7 LYS LYS H . n +H 1 8 GLU 8 8 8 GLU GLU H . n +H 1 9 ALA 9 9 9 ALA ALA H . n +H 1 10 ALA 10 10 10 ALA ALA H . n +H 1 11 ARG 11 11 11 ARG ARG H . n +H 1 12 PRO 12 12 12 PRO PRO H . n +H 1 13 THR 13 13 13 THR THR H . n +H 1 14 LEU 14 14 14 LEU LEU H . n +H 1 15 MET 15 15 15 MET MET H . n +H 1 16 PRO 16 16 16 PRO PRO H . n +H 1 17 ARG 17 17 17 ARG ARG H . n +H 1 18 ALA 18 18 18 ALA ALA H . n +H 1 19 GLN 19 19 19 GLN GLN H . n +H 1 20 SER 20 20 20 SER SER H . n +H 1 21 TYR 21 21 21 TYR TYR H . n +H 1 22 LYS 22 22 22 LYS LYS H . n +H 1 23 ASP 23 23 23 ASP ASP H . n +H 1 24 LEU 24 24 24 LEU LEU H . n +H 1 25 THR 25 25 25 THR THR H . n +H 1 26 HIS 26 26 26 HIS HIS H . n +H 1 27 LEU 27 27 27 LEU LEU H . n +H 1 28 PRO 28 28 28 PRO PRO H . n +H 1 29 ALA 29 29 29 ALA ALA H . n +H 1 30 PRO 30 30 30 PRO PRO H . n +H 1 31 THR 31 31 31 THR THR H . n +H 1 32 GLY 32 32 32 GLY GLY H . n +H 1 33 LYS 33 33 33 LYS LYS H . n +H 1 34 ILE 34 34 34 ILE ILE H . n +H 1 35 PHE 35 35 35 PHE PHE H . n +H 1 36 VAL 36 36 36 VAL VAL H . n +H 1 37 SER 37 37 37 SER SER H . n +H 1 38 VAL 38 38 38 VAL VAL H . n +H 1 39 TYR 39 39 39 TYR TYR H . n +H 1 40 ASN 40 40 40 ASN ASN H . n +H 1 41 ILE 41 41 41 ILE ILE H . n +H 1 42 GLN 42 42 42 GLN GLN H . n +H 1 43 ASP 43 43 43 ASP ASP H . n +H 1 44 GLU 44 44 44 GLU GLU H . n +H 1 45 THR 45 45 45 THR THR H . n +H 1 46 GLY 46 46 46 GLY GLY H . n +H 1 47 GLN 47 47 47 GLN GLN H . n +H 1 48 PHE 48 48 48 PHE PHE H . n +H 1 49 LYS 49 49 49 LYS LYS H . n +H 1 50 PRO 50 50 50 PRO PRO H . n +H 1 51 TYR 51 51 51 TYR TYR H . n +H 1 52 PRO 52 52 52 PRO PRO H . n +H 1 53 ALA 53 53 53 ALA ALA H . n +H 1 54 SER 54 54 54 SER SER H . n +H 1 55 ASN 55 55 55 ASN ASN H . n +H 1 56 PHE 56 56 56 PHE PHE H . n +H 1 57 SER 57 57 57 SER SER H . n +H 1 58 THR 58 58 58 THR THR H . n +H 1 59 ALA 59 59 59 ALA ALA H . n +H 1 60 VAL 60 60 60 VAL VAL H . n +H 1 61 PRO 61 61 61 PRO PRO H . n +H 1 62 GLN 62 62 62 GLN GLN H . n +H 1 63 SER 63 63 63 SER SER H . n +H 1 64 ALA 64 64 64 ALA ALA H . n +H 1 65 THR 65 65 65 THR THR H . n +H 1 66 ALA 66 66 66 ALA ALA H . n +H 1 67 MET 67 67 67 MET MET H . n +H 1 68 LEU 68 68 68 LEU LEU H . n +H 1 69 VAL 69 69 69 VAL VAL H . n +H 1 70 THR 70 70 70 THR THR H . n +H 1 71 ALA 71 71 71 ALA ALA H . n +H 1 72 LEU 72 72 72 LEU LEU H . n +H 1 73 LYS 73 73 73 LYS LYS H . n +H 1 74 ASP 74 74 74 ASP ASP H . n +H 1 75 SER 75 75 75 SER SER H . n +H 1 76 ARG 76 76 76 ARG ARG H . n +H 1 77 TRP 77 77 77 TRP TRP H . n +H 1 78 PHE 78 78 78 PHE PHE H . n +H 1 79 ILE 79 79 79 ILE ILE H . n +H 1 80 PRO 80 80 80 PRO PRO H . n +H 1 81 LEU 81 81 81 LEU LEU H . n +H 1 82 GLU 82 82 82 GLU GLU H . n +H 1 83 ARG 83 83 83 ARG ARG H . n +H 1 84 GLN 84 84 84 GLN GLN H . n +H 1 85 GLY 85 85 85 GLY GLY H . n +H 1 86 LEU 86 86 86 LEU LEU H . n +H 1 87 GLN 87 87 87 GLN GLN H . n +H 1 88 ASN 88 88 88 ASN ASN H . n +H 1 89 LEU 89 89 89 LEU LEU H . n +H 1 90 LEU 90 90 90 LEU LEU H . n +H 1 91 ASN 91 91 91 ASN ASN H . n +H 1 92 GLU 92 92 92 GLU GLU H . n +H 1 93 ARG 93 93 93 ARG ARG H . n +H 1 94 LYS 94 94 94 LYS LYS H . n +H 1 95 ILE 95 95 95 ILE ILE H . n +H 1 96 ILE 96 96 96 ILE ILE H . n +H 1 97 ARG 97 97 97 ARG ARG H . n +H 1 98 ALA 98 98 98 ALA ALA H . n +H 1 99 ALA 99 99 99 ALA ALA H . n +H 1 100 GLN 100 100 100 GLN GLN H . n +H 1 101 GLU 101 101 101 GLU GLU H . n +H 1 102 ASN 102 102 102 ASN ASN H . n +H 1 103 GLY 103 103 103 GLY GLY H . n +H 1 104 THR 104 104 104 THR THR H . n +H 1 105 VAL 105 105 105 VAL VAL H . n +H 1 106 ALA 106 106 106 ALA ALA H . n +H 1 107 ILE 107 107 107 ILE ILE H . n +H 1 108 ASN 108 108 108 ASN ASN H . n +H 1 109 ASN 109 109 109 ASN ASN H . n +H 1 110 ARG 110 110 110 ARG ARG H . n +H 1 111 ILE 111 111 111 ILE ILE H . n +H 1 112 PRO 112 112 112 PRO PRO H . n +H 1 113 LEU 113 113 113 LEU LEU H . n +H 1 114 GLN 114 114 114 GLN GLN H . n +H 1 115 SER 115 115 115 SER SER H . n +H 1 116 LEU 116 116 116 LEU LEU H . n +H 1 117 THR 117 117 117 THR THR H . n +H 1 118 ALA 118 118 118 ALA ALA H . n +H 1 119 ALA 119 119 119 ALA ALA H . n +H 1 120 ASN 120 120 120 ASN ASN H . n +H 1 121 ILE 121 121 121 ILE ILE H . n +H 1 122 MET 122 122 122 MET MET H . n +H 1 123 VAL 123 123 123 VAL VAL H . n +H 1 124 GLU 124 124 124 GLU GLU H . n +H 1 125 GLY 125 125 125 GLY GLY H . n +H 1 126 SER 126 126 126 SER SER H . n +H 1 127 ILE 127 127 127 ILE ILE H . n +H 1 128 ILE 128 128 128 ILE ILE H . n +H 1 129 GLY 129 129 129 GLY GLY H . n +H 1 130 TYR 130 130 130 TYR TYR H . n +H 1 131 GLU 131 131 131 GLU GLU H . n +H 1 132 SER 132 132 132 SER SER H . n +H 1 133 ASN 133 133 133 ASN ASN H . n +H 1 134 VAL 134 134 134 VAL VAL H . n +H 1 135 LYS 135 135 135 LYS LYS H . n +H 1 136 SER 136 136 136 SER SER H . n +H 1 137 GLY 137 137 137 GLY GLY H . n +H 1 138 GLY 138 138 138 GLY GLY H . n +H 1 139 VAL 139 139 139 VAL VAL H . n +H 1 140 GLY 140 140 140 GLY GLY H . n +H 1 141 ALA 141 141 141 ALA ALA H . n +H 1 142 ARG 142 142 142 ARG ARG H . n +H 1 143 TYR 143 143 143 TYR TYR H . n +H 1 144 PHE 144 144 ? ? ? H . n +H 1 145 GLY 145 145 145 GLY GLY H . n +H 1 146 ILE 146 146 146 ILE ILE H . n +H 1 147 GLY 147 147 147 GLY GLY H . n +H 1 148 ALA 148 148 148 ALA ALA H . n +H 1 149 ASP 149 149 149 ASP ASP H . n +H 1 150 THR 150 150 150 THR THR H . n +H 1 151 GLN 151 151 151 GLN GLN H . n +H 1 152 TYR 152 152 152 TYR TYR H . n +H 1 153 GLN 153 153 153 GLN GLN H . n +H 1 154 LEU 154 154 154 LEU LEU H . n +H 1 155 ASP 155 155 155 ASP ASP H . n +H 1 156 GLN 156 156 156 GLN GLN H . n +H 1 157 ILE 157 157 157 ILE ILE H . n +H 1 158 ALA 158 158 158 ALA ALA H . n +H 1 159 VAL 159 159 159 VAL VAL H . n +H 1 160 ASN 160 160 160 ASN ASN H . n +H 1 161 LEU 161 161 161 LEU LEU H . n +H 1 162 ARG 162 162 162 ARG ARG H . n +H 1 163 VAL 163 163 163 VAL VAL H . n +H 1 164 VAL 164 164 164 VAL VAL H . n +H 1 165 ASN 165 165 165 ASN ASN H . n +H 1 166 VAL 166 166 166 VAL VAL H . n +H 1 167 SER 167 167 167 SER SER H . n +H 1 168 THR 168 168 168 THR THR H . n +H 1 169 GLY 169 169 169 GLY GLY H . n +H 1 170 GLU 170 170 170 GLU GLU H . n +H 1 171 ILE 171 171 171 ILE ILE H . n +H 1 172 LEU 172 172 172 LEU LEU H . n +H 1 173 SER 173 173 173 SER SER H . n +H 1 174 SER 174 174 174 SER SER H . n +H 1 175 VAL 175 175 175 VAL VAL H . n +H 1 176 ASN 176 176 176 ASN ASN H . n +H 1 177 THR 177 177 177 THR THR H . n +H 1 178 SER 178 178 178 SER SER H . n +H 1 179 LYS 179 179 179 LYS LYS H . n +H 1 180 THR 180 180 180 THR THR H . n +H 1 181 ILE 181 181 181 ILE ILE H . n +H 1 182 LEU 182 182 182 LEU LEU H . n +H 1 183 SER 183 183 183 SER SER H . n +H 1 184 TYR 184 184 184 TYR TYR H . n +H 1 185 GLU 185 185 185 GLU GLU H . n +H 1 186 VAL 186 186 186 VAL VAL H . n +H 1 187 GLN 187 187 187 GLN GLN H . n +H 1 188 ALA 188 188 188 ALA ALA H . n +H 1 189 GLY 189 189 189 GLY GLY H . n +H 1 190 VAL 190 190 190 VAL VAL H . n +H 1 191 PHE 191 191 191 PHE PHE H . n +H 1 192 ARG 192 192 192 ARG ARG H . n +H 1 193 PHE 193 193 ? ? ? H . n +H 1 194 ILE 194 194 ? ? ? H . n +H 1 195 ASP 195 195 ? ? ? H . n +H 1 196 TYR 196 196 ? ? ? H . n +H 1 197 GLN 197 197 ? ? ? H . n +H 1 198 ARG 198 198 ? ? ? H . n +H 1 199 LEU 199 199 ? ? ? H . n +H 1 200 LEU 200 200 200 LEU LEU H . n +H 1 201 GLU 201 201 201 GLU GLU H . n +H 1 202 GLY 202 202 202 GLY GLY H . n +H 1 203 GLU 203 203 203 GLU GLU H . n +H 1 204 VAL 204 204 204 VAL VAL H . n +H 1 205 GLY 205 205 205 GLY GLY H . n +H 1 206 TYR 206 206 206 TYR TYR H . n +H 1 207 THR 207 207 207 THR THR H . n +H 1 208 SER 208 208 208 SER SER H . n +H 1 209 ASN 209 209 209 ASN ASN H . n +H 1 210 GLU 210 210 210 GLU GLU H . n +H 1 211 PRO 211 211 211 PRO PRO H . n +H 1 212 VAL 212 212 212 VAL VAL H . n +H 1 213 MET 213 213 213 MET MET H . n +H 1 214 LEU 214 214 214 LEU LEU H . n +H 1 215 CYS 215 215 215 CYS CYS H . n +H 1 216 LEU 216 216 216 LEU LEU H . n +H 1 217 MET 217 217 217 MET MET H . n +H 1 218 SER 218 218 218 SER SER H . n +H 1 219 ALA 219 219 219 ALA ALA H . n +H 1 220 ILE 220 220 220 ILE ILE H . n +H 1 221 GLU 221 221 221 GLU GLU H . n +H 1 222 THR 222 222 222 THR THR H . n +H 1 223 GLY 223 223 223 GLY GLY H . n +H 1 224 VAL 224 224 224 VAL VAL H . n +H 1 225 ILE 225 225 225 ILE ILE H . n +H 1 226 PHE 226 226 226 PHE PHE H . n +H 1 227 LEU 227 227 227 LEU LEU H . n +H 1 228 ILE 228 228 228 ILE ILE H . n +H 1 229 ASN 229 229 229 ASN ASN H . n +H 1 230 ASP 230 230 230 ASP ASP H . n +H 1 231 GLY 231 231 231 GLY GLY H . n +H 1 232 ILE 232 232 232 ILE ILE H . n +H 1 233 ASP 233 233 233 ASP ASP H . n +H 1 234 ARG 234 234 234 ARG ARG H . n +H 1 235 GLY 235 235 235 GLY GLY H . n +H 1 236 LEU 236 236 236 LEU LEU H . n +H 1 237 TRP 237 237 237 TRP TRP H . n +H 1 238 ASP 238 238 238 ASP ASP H . n +H 1 239 LEU 239 239 239 LEU LEU H . n +H 1 240 GLN 240 240 240 GLN GLN H . n +H 1 241 ASN 241 241 241 ASN ASN H . n +H 1 242 LYS 242 242 242 LYS LYS H . n +H 1 243 ALA 243 243 243 ALA ALA H . n +H 1 244 GLU 244 244 244 GLU GLU H . n +H 1 245 ARG 245 245 245 ARG ARG H . n +H 1 246 GLN 246 246 246 GLN GLN H . n +H 1 247 ASN 247 247 247 ASN ASN H . n +H 1 248 ASP 248 248 248 ASP ASP H . n +H 1 249 ILE 249 249 249 ILE ILE H . n +H 1 250 LEU 250 250 250 LEU LEU H . n +H 1 251 VAL 251 251 251 VAL VAL H . n +H 1 252 LYS 252 252 252 LYS LYS H . n +H 1 253 TYR 253 253 253 TYR TYR H . n +H 1 254 ARG 254 254 254 ARG ARG H . n +H 1 255 HIS 255 255 255 HIS HIS H . n +H 1 256 MET 256 256 256 MET MET H . n +H 1 257 SER 257 257 257 SER SER H . n +H 1 258 VAL 258 258 ? ? ? H . n +H 1 259 PRO 259 259 ? ? ? H . n +H 1 260 PRO 260 260 ? ? ? H . n +H 1 261 GLU 261 261 ? ? ? H . n +H 1 262 SER 262 262 ? ? ? H . n +I 1 1 CYS 1 1 ? ? ? I . n +I 1 2 LEU 2 2 2 LEU LEU I . n +I 1 3 THR 3 3 3 THR THR I . n +I 1 4 ALA 4 4 4 ALA ALA I . n +I 1 5 PRO 5 5 5 PRO PRO I . n +I 1 6 PRO 6 6 6 PRO PRO I . n +I 1 7 LYS 7 7 7 LYS LYS I . n +I 1 8 GLU 8 8 8 GLU GLU I . n +I 1 9 ALA 9 9 9 ALA ALA I . n +I 1 10 ALA 10 10 10 ALA ALA I . n +I 1 11 ARG 11 11 11 ARG ARG I . n +I 1 12 PRO 12 12 12 PRO PRO I . n +I 1 13 THR 13 13 13 THR THR I . n +I 1 14 LEU 14 14 14 LEU LEU I . n +I 1 15 MET 15 15 15 MET MET I . n +I 1 16 PRO 16 16 16 PRO PRO I . n +I 1 17 ARG 17 17 17 ARG ARG I . n +I 1 18 ALA 18 18 18 ALA ALA I . n +I 1 19 GLN 19 19 19 GLN GLN I . n +I 1 20 SER 20 20 20 SER SER I . n +I 1 21 TYR 21 21 21 TYR TYR I . n +I 1 22 LYS 22 22 22 LYS LYS I . n +I 1 23 ASP 23 23 23 ASP ASP I . n +I 1 24 LEU 24 24 24 LEU LEU I . n +I 1 25 THR 25 25 25 THR THR I . n +I 1 26 HIS 26 26 26 HIS HIS I . n +I 1 27 LEU 27 27 27 LEU LEU I . n +I 1 28 PRO 28 28 28 PRO PRO I . n +I 1 29 ALA 29 29 29 ALA ALA I . n +I 1 30 PRO 30 30 30 PRO PRO I . n +I 1 31 THR 31 31 31 THR THR I . n +I 1 32 GLY 32 32 32 GLY GLY I . n +I 1 33 LYS 33 33 33 LYS LYS I . n +I 1 34 ILE 34 34 34 ILE ILE I . n +I 1 35 PHE 35 35 35 PHE PHE I . n +I 1 36 VAL 36 36 36 VAL VAL I . n +I 1 37 SER 37 37 37 SER SER I . n +I 1 38 VAL 38 38 38 VAL VAL I . n +I 1 39 TYR 39 39 39 TYR TYR I . n +I 1 40 ASN 40 40 40 ASN ASN I . n +I 1 41 ILE 41 41 41 ILE ILE I . n +I 1 42 GLN 42 42 42 GLN GLN I . n +I 1 43 ASP 43 43 43 ASP ASP I . n +I 1 44 GLU 44 44 44 GLU GLU I . n +I 1 45 THR 45 45 45 THR THR I . n +I 1 46 GLY 46 46 46 GLY GLY I . n +I 1 47 GLN 47 47 47 GLN GLN I . n +I 1 48 PHE 48 48 48 PHE PHE I . n +I 1 49 LYS 49 49 49 LYS LYS I . n +I 1 50 PRO 50 50 50 PRO PRO I . n +I 1 51 TYR 51 51 51 TYR TYR I . n +I 1 52 PRO 52 52 52 PRO PRO I . n +I 1 53 ALA 53 53 53 ALA ALA I . n +I 1 54 SER 54 54 54 SER SER I . n +I 1 55 ASN 55 55 55 ASN ASN I . n +I 1 56 PHE 56 56 56 PHE PHE I . n +I 1 57 SER 57 57 57 SER SER I . n +I 1 58 THR 58 58 58 THR THR I . n +I 1 59 ALA 59 59 59 ALA ALA I . n +I 1 60 VAL 60 60 60 VAL VAL I . n +I 1 61 PRO 61 61 61 PRO PRO I . n +I 1 62 GLN 62 62 62 GLN GLN I . n +I 1 63 SER 63 63 63 SER SER I . n +I 1 64 ALA 64 64 64 ALA ALA I . n +I 1 65 THR 65 65 65 THR THR I . n +I 1 66 ALA 66 66 66 ALA ALA I . n +I 1 67 MET 67 67 67 MET MET I . n +I 1 68 LEU 68 68 68 LEU LEU I . n +I 1 69 VAL 69 69 69 VAL VAL I . n +I 1 70 THR 70 70 70 THR THR I . n +I 1 71 ALA 71 71 71 ALA ALA I . n +I 1 72 LEU 72 72 72 LEU LEU I . n +I 1 73 LYS 73 73 73 LYS LYS I . n +I 1 74 ASP 74 74 74 ASP ASP I . n +I 1 75 SER 75 75 75 SER SER I . n +I 1 76 ARG 76 76 76 ARG ARG I . n +I 1 77 TRP 77 77 77 TRP TRP I . n +I 1 78 PHE 78 78 78 PHE PHE I . n +I 1 79 ILE 79 79 79 ILE ILE I . n +I 1 80 PRO 80 80 80 PRO PRO I . n +I 1 81 LEU 81 81 81 LEU LEU I . n +I 1 82 GLU 82 82 82 GLU GLU I . n +I 1 83 ARG 83 83 83 ARG ARG I . n +I 1 84 GLN 84 84 84 GLN GLN I . n +I 1 85 GLY 85 85 85 GLY GLY I . n +I 1 86 LEU 86 86 86 LEU LEU I . n +I 1 87 GLN 87 87 87 GLN GLN I . n +I 1 88 ASN 88 88 88 ASN ASN I . n +I 1 89 LEU 89 89 89 LEU LEU I . n +I 1 90 LEU 90 90 90 LEU LEU I . n +I 1 91 ASN 91 91 91 ASN ASN I . n +I 1 92 GLU 92 92 92 GLU GLU I . n +I 1 93 ARG 93 93 93 ARG ARG I . n +I 1 94 LYS 94 94 94 LYS LYS I . n +I 1 95 ILE 95 95 95 ILE ILE I . n +I 1 96 ILE 96 96 96 ILE ILE I . n +I 1 97 ARG 97 97 97 ARG ARG I . n +I 1 98 ALA 98 98 98 ALA ALA I . n +I 1 99 ALA 99 99 99 ALA ALA I . n +I 1 100 GLN 100 100 100 GLN GLN I . n +I 1 101 GLU 101 101 101 GLU GLU I . n +I 1 102 ASN 102 102 102 ASN ASN I . n +I 1 103 GLY 103 103 103 GLY GLY I . n +I 1 104 THR 104 104 104 THR THR I . n +I 1 105 VAL 105 105 105 VAL VAL I . n +I 1 106 ALA 106 106 106 ALA ALA I . n +I 1 107 ILE 107 107 107 ILE ILE I . n +I 1 108 ASN 108 108 108 ASN ASN I . n +I 1 109 ASN 109 109 109 ASN ASN I . n +I 1 110 ARG 110 110 110 ARG ARG I . n +I 1 111 ILE 111 111 111 ILE ILE I . n +I 1 112 PRO 112 112 112 PRO PRO I . n +I 1 113 LEU 113 113 113 LEU LEU I . n +I 1 114 GLN 114 114 114 GLN GLN I . n +I 1 115 SER 115 115 115 SER SER I . n +I 1 116 LEU 116 116 116 LEU LEU I . n +I 1 117 THR 117 117 117 THR THR I . n +I 1 118 ALA 118 118 118 ALA ALA I . n +I 1 119 ALA 119 119 119 ALA ALA I . n +I 1 120 ASN 120 120 120 ASN ASN I . n +I 1 121 ILE 121 121 121 ILE ILE I . n +I 1 122 MET 122 122 122 MET MET I . n +I 1 123 VAL 123 123 123 VAL VAL I . n +I 1 124 GLU 124 124 124 GLU GLU I . n +I 1 125 GLY 125 125 125 GLY GLY I . n +I 1 126 SER 126 126 126 SER SER I . n +I 1 127 ILE 127 127 127 ILE ILE I . n +I 1 128 ILE 128 128 128 ILE ILE I . n +I 1 129 GLY 129 129 129 GLY GLY I . n +I 1 130 TYR 130 130 130 TYR TYR I . n +I 1 131 GLU 131 131 131 GLU GLU I . n +I 1 132 SER 132 132 132 SER SER I . n +I 1 133 ASN 133 133 133 ASN ASN I . n +I 1 134 VAL 134 134 134 VAL VAL I . n +I 1 135 LYS 135 135 135 LYS LYS I . n +I 1 136 SER 136 136 136 SER SER I . n +I 1 137 GLY 137 137 137 GLY GLY I . n +I 1 138 GLY 138 138 138 GLY GLY I . n +I 1 139 VAL 139 139 139 VAL VAL I . n +I 1 140 GLY 140 140 140 GLY GLY I . n +I 1 141 ALA 141 141 141 ALA ALA I . n +I 1 142 ARG 142 142 142 ARG ARG I . n +I 1 143 TYR 143 143 143 TYR TYR I . n +I 1 144 PHE 144 144 ? ? ? I . n +I 1 145 GLY 145 145 145 GLY GLY I . n +I 1 146 ILE 146 146 146 ILE ILE I . n +I 1 147 GLY 147 147 147 GLY GLY I . n +I 1 148 ALA 148 148 148 ALA ALA I . n +I 1 149 ASP 149 149 149 ASP ASP I . n +I 1 150 THR 150 150 150 THR THR I . n +I 1 151 GLN 151 151 151 GLN GLN I . n +I 1 152 TYR 152 152 152 TYR TYR I . n +I 1 153 GLN 153 153 153 GLN GLN I . n +I 1 154 LEU 154 154 154 LEU LEU I . n +I 1 155 ASP 155 155 155 ASP ASP I . n +I 1 156 GLN 156 156 156 GLN GLN I . n +I 1 157 ILE 157 157 157 ILE ILE I . n +I 1 158 ALA 158 158 158 ALA ALA I . n +I 1 159 VAL 159 159 159 VAL VAL I . n +I 1 160 ASN 160 160 160 ASN ASN I . n +I 1 161 LEU 161 161 161 LEU LEU I . n +I 1 162 ARG 162 162 162 ARG ARG I . n +I 1 163 VAL 163 163 163 VAL VAL I . n +I 1 164 VAL 164 164 164 VAL VAL I . n +I 1 165 ASN 165 165 165 ASN ASN I . n +I 1 166 VAL 166 166 166 VAL VAL I . n +I 1 167 SER 167 167 167 SER SER I . n +I 1 168 THR 168 168 168 THR THR I . n +I 1 169 GLY 169 169 169 GLY GLY I . n +I 1 170 GLU 170 170 170 GLU GLU I . n +I 1 171 ILE 171 171 171 ILE ILE I . n +I 1 172 LEU 172 172 172 LEU LEU I . n +I 1 173 SER 173 173 173 SER SER I . n +I 1 174 SER 174 174 174 SER SER I . n +I 1 175 VAL 175 175 175 VAL VAL I . n +I 1 176 ASN 176 176 176 ASN ASN I . n +I 1 177 THR 177 177 177 THR THR I . n +I 1 178 SER 178 178 178 SER SER I . n +I 1 179 LYS 179 179 179 LYS LYS I . n +I 1 180 THR 180 180 180 THR THR I . n +I 1 181 ILE 181 181 181 ILE ILE I . n +I 1 182 LEU 182 182 182 LEU LEU I . n +I 1 183 SER 183 183 183 SER SER I . n +I 1 184 TYR 184 184 184 TYR TYR I . n +I 1 185 GLU 185 185 185 GLU GLU I . n +I 1 186 VAL 186 186 186 VAL VAL I . n +I 1 187 GLN 187 187 187 GLN GLN I . n +I 1 188 ALA 188 188 188 ALA ALA I . n +I 1 189 GLY 189 189 189 GLY GLY I . n +I 1 190 VAL 190 190 190 VAL VAL I . n +I 1 191 PHE 191 191 191 PHE PHE I . n +I 1 192 ARG 192 192 ? ? ? I . n +I 1 193 PHE 193 193 ? ? ? I . n +I 1 194 ILE 194 194 ? ? ? I . n +I 1 195 ASP 195 195 ? ? ? I . n +I 1 196 TYR 196 196 ? ? ? I . n +I 1 197 GLN 197 197 ? ? ? I . n +I 1 198 ARG 198 198 ? ? ? I . n +I 1 199 LEU 199 199 ? ? ? I . n +I 1 200 LEU 200 200 200 LEU LEU I . n +I 1 201 GLU 201 201 201 GLU GLU I . n +I 1 202 GLY 202 202 202 GLY GLY I . n +I 1 203 GLU 203 203 203 GLU GLU I . n +I 1 204 VAL 204 204 204 VAL VAL I . n +I 1 205 GLY 205 205 205 GLY GLY I . n +I 1 206 TYR 206 206 206 TYR TYR I . n +I 1 207 THR 207 207 207 THR THR I . n +I 1 208 SER 208 208 208 SER SER I . n +I 1 209 ASN 209 209 209 ASN ASN I . n +I 1 210 GLU 210 210 210 GLU GLU I . n +I 1 211 PRO 211 211 211 PRO PRO I . n +I 1 212 VAL 212 212 212 VAL VAL I . n +I 1 213 MET 213 213 213 MET MET I . n +I 1 214 LEU 214 214 214 LEU LEU I . n +I 1 215 CYS 215 215 215 CYS CYS I . n +I 1 216 LEU 216 216 216 LEU LEU I . n +I 1 217 MET 217 217 217 MET MET I . n +I 1 218 SER 218 218 218 SER SER I . n +I 1 219 ALA 219 219 219 ALA ALA I . n +I 1 220 ILE 220 220 220 ILE ILE I . n +I 1 221 GLU 221 221 221 GLU GLU I . n +I 1 222 THR 222 222 222 THR THR I . n +I 1 223 GLY 223 223 223 GLY GLY I . n +I 1 224 VAL 224 224 224 VAL VAL I . n +I 1 225 ILE 225 225 225 ILE ILE I . n +I 1 226 PHE 226 226 226 PHE PHE I . n +I 1 227 LEU 227 227 227 LEU LEU I . n +I 1 228 ILE 228 228 228 ILE ILE I . n +I 1 229 ASN 229 229 229 ASN ASN I . n +I 1 230 ASP 230 230 230 ASP ASP I . n +I 1 231 GLY 231 231 231 GLY GLY I . n +I 1 232 ILE 232 232 232 ILE ILE I . n +I 1 233 ASP 233 233 233 ASP ASP I . n +I 1 234 ARG 234 234 234 ARG ARG I . n +I 1 235 GLY 235 235 235 GLY GLY I . n +I 1 236 LEU 236 236 236 LEU LEU I . n +I 1 237 TRP 237 237 237 TRP TRP I . n +I 1 238 ASP 238 238 238 ASP ASP I . n +I 1 239 LEU 239 239 239 LEU LEU I . n +I 1 240 GLN 240 240 240 GLN GLN I . n +I 1 241 ASN 241 241 241 ASN ASN I . n +I 1 242 LYS 242 242 242 LYS LYS I . n +I 1 243 ALA 243 243 243 ALA ALA I . n +I 1 244 GLU 244 244 244 GLU GLU I . n +I 1 245 ARG 245 245 245 ARG ARG I . n +I 1 246 GLN 246 246 246 GLN GLN I . n +I 1 247 ASN 247 247 247 ASN ASN I . n +I 1 248 ASP 248 248 248 ASP ASP I . n +I 1 249 ILE 249 249 249 ILE ILE I . n +I 1 250 LEU 250 250 250 LEU LEU I . n +I 1 251 VAL 251 251 251 VAL VAL I . n +I 1 252 LYS 252 252 252 LYS LYS I . n +I 1 253 TYR 253 253 253 TYR TYR I . n +I 1 254 ARG 254 254 254 ARG ARG I . n +I 1 255 HIS 255 255 255 HIS HIS I . n +I 1 256 MET 256 256 256 MET MET I . n +I 1 257 SER 257 257 257 SER SER I . n +I 1 258 VAL 258 258 ? ? ? I . n +I 1 259 PRO 259 259 ? ? ? I . n +I 1 260 PRO 260 260 ? ? ? I . n +I 1 261 GLU 261 261 ? ? ? I . n +I 1 262 SER 262 262 ? ? ? I . n +J 1 1 CYS 1 1 ? ? ? J . n +J 1 2 LEU 2 2 2 LEU LEU J . n +J 1 3 THR 3 3 3 THR THR J . n +J 1 4 ALA 4 4 4 ALA ALA J . n +J 1 5 PRO 5 5 5 PRO PRO J . n +J 1 6 PRO 6 6 6 PRO PRO J . n +J 1 7 LYS 7 7 7 LYS LYS J . n +J 1 8 GLU 8 8 8 GLU GLU J . n +J 1 9 ALA 9 9 9 ALA ALA J . n +J 1 10 ALA 10 10 10 ALA ALA J . n +J 1 11 ARG 11 11 11 ARG ARG J . n +J 1 12 PRO 12 12 12 PRO PRO J . n +J 1 13 THR 13 13 13 THR THR J . n +J 1 14 LEU 14 14 14 LEU LEU J . n +J 1 15 MET 15 15 15 MET MET J . n +J 1 16 PRO 16 16 16 PRO PRO J . n +J 1 17 ARG 17 17 17 ARG ARG J . n +J 1 18 ALA 18 18 18 ALA ALA J . n +J 1 19 GLN 19 19 19 GLN GLN J . n +J 1 20 SER 20 20 20 SER SER J . n +J 1 21 TYR 21 21 21 TYR TYR J . n +J 1 22 LYS 22 22 22 LYS LYS J . n +J 1 23 ASP 23 23 23 ASP ASP J . n +J 1 24 LEU 24 24 24 LEU LEU J . n +J 1 25 THR 25 25 25 THR THR J . n +J 1 26 HIS 26 26 26 HIS HIS J . n +J 1 27 LEU 27 27 27 LEU LEU J . n +J 1 28 PRO 28 28 28 PRO PRO J . n +J 1 29 ALA 29 29 29 ALA ALA J . n +J 1 30 PRO 30 30 30 PRO PRO J . n +J 1 31 THR 31 31 31 THR THR J . n +J 1 32 GLY 32 32 32 GLY GLY J . n +J 1 33 LYS 33 33 33 LYS LYS J . n +J 1 34 ILE 34 34 34 ILE ILE J . n +J 1 35 PHE 35 35 35 PHE PHE J . n +J 1 36 VAL 36 36 36 VAL VAL J . n +J 1 37 SER 37 37 37 SER SER J . n +J 1 38 VAL 38 38 38 VAL VAL J . n +J 1 39 TYR 39 39 39 TYR TYR J . n +J 1 40 ASN 40 40 40 ASN ASN J . n +J 1 41 ILE 41 41 41 ILE ILE J . n +J 1 42 GLN 42 42 42 GLN GLN J . n +J 1 43 ASP 43 43 43 ASP ASP J . n +J 1 44 GLU 44 44 44 GLU GLU J . n +J 1 45 THR 45 45 45 THR THR J . n +J 1 46 GLY 46 46 46 GLY GLY J . n +J 1 47 GLN 47 47 47 GLN GLN J . n +J 1 48 PHE 48 48 48 PHE PHE J . n +J 1 49 LYS 49 49 49 LYS LYS J . n +J 1 50 PRO 50 50 50 PRO PRO J . n +J 1 51 TYR 51 51 51 TYR TYR J . n +J 1 52 PRO 52 52 52 PRO PRO J . n +J 1 53 ALA 53 53 53 ALA ALA J . n +J 1 54 SER 54 54 54 SER SER J . n +J 1 55 ASN 55 55 55 ASN ASN J . n +J 1 56 PHE 56 56 56 PHE PHE J . n +J 1 57 SER 57 57 57 SER SER J . n +J 1 58 THR 58 58 58 THR THR J . n +J 1 59 ALA 59 59 59 ALA ALA J . n +J 1 60 VAL 60 60 60 VAL VAL J . n +J 1 61 PRO 61 61 61 PRO PRO J . n +J 1 62 GLN 62 62 62 GLN GLN J . n +J 1 63 SER 63 63 63 SER SER J . n +J 1 64 ALA 64 64 64 ALA ALA J . n +J 1 65 THR 65 65 65 THR THR J . n +J 1 66 ALA 66 66 66 ALA ALA J . n +J 1 67 MET 67 67 67 MET MET J . n +J 1 68 LEU 68 68 68 LEU LEU J . n +J 1 69 VAL 69 69 69 VAL VAL J . n +J 1 70 THR 70 70 70 THR THR J . n +J 1 71 ALA 71 71 71 ALA ALA J . n +J 1 72 LEU 72 72 72 LEU LEU J . n +J 1 73 LYS 73 73 73 LYS LYS J . n +J 1 74 ASP 74 74 74 ASP ASP J . n +J 1 75 SER 75 75 75 SER SER J . n +J 1 76 ARG 76 76 76 ARG ARG J . n +J 1 77 TRP 77 77 77 TRP TRP J . n +J 1 78 PHE 78 78 78 PHE PHE J . n +J 1 79 ILE 79 79 79 ILE ILE J . n +J 1 80 PRO 80 80 80 PRO PRO J . n +J 1 81 LEU 81 81 81 LEU LEU J . n +J 1 82 GLU 82 82 82 GLU GLU J . n +J 1 83 ARG 83 83 83 ARG ARG J . n +J 1 84 GLN 84 84 84 GLN GLN J . n +J 1 85 GLY 85 85 85 GLY GLY J . n +J 1 86 LEU 86 86 86 LEU LEU J . n +J 1 87 GLN 87 87 87 GLN GLN J . n +J 1 88 ASN 88 88 88 ASN ASN J . n +J 1 89 LEU 89 89 89 LEU LEU J . n +J 1 90 LEU 90 90 90 LEU LEU J . n +J 1 91 ASN 91 91 91 ASN ASN J . n +J 1 92 GLU 92 92 92 GLU GLU J . n +J 1 93 ARG 93 93 93 ARG ARG J . n +J 1 94 LYS 94 94 94 LYS LYS J . n +J 1 95 ILE 95 95 95 ILE ILE J . n +J 1 96 ILE 96 96 96 ILE ILE J . n +J 1 97 ARG 97 97 97 ARG ARG J . n +J 1 98 ALA 98 98 98 ALA ALA J . n +J 1 99 ALA 99 99 99 ALA ALA J . n +J 1 100 GLN 100 100 100 GLN GLN J . n +J 1 101 GLU 101 101 101 GLU GLU J . n +J 1 102 ASN 102 102 102 ASN ASN J . n +J 1 103 GLY 103 103 103 GLY GLY J . n +J 1 104 THR 104 104 104 THR THR J . n +J 1 105 VAL 105 105 105 VAL VAL J . n +J 1 106 ALA 106 106 106 ALA ALA J . n +J 1 107 ILE 107 107 107 ILE ILE J . n +J 1 108 ASN 108 108 108 ASN ASN J . n +J 1 109 ASN 109 109 109 ASN ASN J . n +J 1 110 ARG 110 110 110 ARG ARG J . n +J 1 111 ILE 111 111 111 ILE ILE J . n +J 1 112 PRO 112 112 112 PRO PRO J . n +J 1 113 LEU 113 113 113 LEU LEU J . n +J 1 114 GLN 114 114 114 GLN GLN J . n +J 1 115 SER 115 115 115 SER SER J . n +J 1 116 LEU 116 116 116 LEU LEU J . n +J 1 117 THR 117 117 117 THR THR J . n +J 1 118 ALA 118 118 118 ALA ALA J . n +J 1 119 ALA 119 119 119 ALA ALA J . n +J 1 120 ASN 120 120 120 ASN ASN J . n +J 1 121 ILE 121 121 121 ILE ILE J . n +J 1 122 MET 122 122 122 MET MET J . n +J 1 123 VAL 123 123 123 VAL VAL J . n +J 1 124 GLU 124 124 124 GLU GLU J . n +J 1 125 GLY 125 125 125 GLY GLY J . n +J 1 126 SER 126 126 126 SER SER J . n +J 1 127 ILE 127 127 127 ILE ILE J . n +J 1 128 ILE 128 128 128 ILE ILE J . n +J 1 129 GLY 129 129 129 GLY GLY J . n +J 1 130 TYR 130 130 130 TYR TYR J . n +J 1 131 GLU 131 131 131 GLU GLU J . n +J 1 132 SER 132 132 132 SER SER J . n +J 1 133 ASN 133 133 133 ASN ASN J . n +J 1 134 VAL 134 134 134 VAL VAL J . n +J 1 135 LYS 135 135 135 LYS LYS J . n +J 1 136 SER 136 136 136 SER SER J . n +J 1 137 GLY 137 137 137 GLY GLY J . n +J 1 138 GLY 138 138 138 GLY GLY J . n +J 1 139 VAL 139 139 139 VAL VAL J . n +J 1 140 GLY 140 140 140 GLY GLY J . n +J 1 141 ALA 141 141 141 ALA ALA J . n +J 1 142 ARG 142 142 142 ARG ARG J . n +J 1 143 TYR 143 143 143 TYR TYR J . n +J 1 144 PHE 144 144 ? ? ? J . n +J 1 145 GLY 145 145 145 GLY GLY J . n +J 1 146 ILE 146 146 146 ILE ILE J . n +J 1 147 GLY 147 147 147 GLY GLY J . n +J 1 148 ALA 148 148 148 ALA ALA J . n +J 1 149 ASP 149 149 149 ASP ASP J . n +J 1 150 THR 150 150 150 THR THR J . n +J 1 151 GLN 151 151 151 GLN GLN J . n +J 1 152 TYR 152 152 152 TYR TYR J . n +J 1 153 GLN 153 153 153 GLN GLN J . n +J 1 154 LEU 154 154 154 LEU LEU J . n +J 1 155 ASP 155 155 155 ASP ASP J . n +J 1 156 GLN 156 156 156 GLN GLN J . n +J 1 157 ILE 157 157 157 ILE ILE J . n +J 1 158 ALA 158 158 158 ALA ALA J . n +J 1 159 VAL 159 159 159 VAL VAL J . n +J 1 160 ASN 160 160 160 ASN ASN J . n +J 1 161 LEU 161 161 161 LEU LEU J . n +J 1 162 ARG 162 162 162 ARG ARG J . n +J 1 163 VAL 163 163 163 VAL VAL J . n +J 1 164 VAL 164 164 164 VAL VAL J . n +J 1 165 ASN 165 165 165 ASN ASN J . n +J 1 166 VAL 166 166 166 VAL VAL J . n +J 1 167 SER 167 167 167 SER SER J . n +J 1 168 THR 168 168 168 THR THR J . n +J 1 169 GLY 169 169 169 GLY GLY J . n +J 1 170 GLU 170 170 170 GLU GLU J . n +J 1 171 ILE 171 171 171 ILE ILE J . n +J 1 172 LEU 172 172 172 LEU LEU J . n +J 1 173 SER 173 173 173 SER SER J . n +J 1 174 SER 174 174 174 SER SER J . n +J 1 175 VAL 175 175 175 VAL VAL J . n +J 1 176 ASN 176 176 176 ASN ASN J . n +J 1 177 THR 177 177 177 THR THR J . n +J 1 178 SER 178 178 178 SER SER J . n +J 1 179 LYS 179 179 179 LYS LYS J . n +J 1 180 THR 180 180 180 THR THR J . n +J 1 181 ILE 181 181 181 ILE ILE J . n +J 1 182 LEU 182 182 182 LEU LEU J . n +J 1 183 SER 183 183 183 SER SER J . n +J 1 184 TYR 184 184 184 TYR TYR J . n +J 1 185 GLU 185 185 185 GLU GLU J . n +J 1 186 VAL 186 186 186 VAL VAL J . n +J 1 187 GLN 187 187 187 GLN GLN J . n +J 1 188 ALA 188 188 188 ALA ALA J . n +J 1 189 GLY 189 189 189 GLY GLY J . n +J 1 190 VAL 190 190 190 VAL VAL J . n +J 1 191 PHE 191 191 191 PHE PHE J . n +J 1 192 ARG 192 192 192 ARG ARG J . n +J 1 193 PHE 193 193 ? ? ? J . n +J 1 194 ILE 194 194 ? ? ? J . n +J 1 195 ASP 195 195 ? ? ? J . n +J 1 196 TYR 196 196 ? ? ? J . n +J 1 197 GLN 197 197 ? ? ? J . n +J 1 198 ARG 198 198 ? ? ? J . n +J 1 199 LEU 199 199 ? ? ? J . n +J 1 200 LEU 200 200 200 LEU LEU J . n +J 1 201 GLU 201 201 201 GLU GLU J . n +J 1 202 GLY 202 202 202 GLY GLY J . n +J 1 203 GLU 203 203 203 GLU GLU J . n +J 1 204 VAL 204 204 204 VAL VAL J . n +J 1 205 GLY 205 205 205 GLY GLY J . n +J 1 206 TYR 206 206 206 TYR TYR J . n +J 1 207 THR 207 207 207 THR THR J . n +J 1 208 SER 208 208 208 SER SER J . n +J 1 209 ASN 209 209 209 ASN ASN J . n +J 1 210 GLU 210 210 210 GLU GLU J . n +J 1 211 PRO 211 211 211 PRO PRO J . n +J 1 212 VAL 212 212 212 VAL VAL J . n +J 1 213 MET 213 213 213 MET MET J . n +J 1 214 LEU 214 214 214 LEU LEU J . n +J 1 215 CYS 215 215 215 CYS CYS J . n +J 1 216 LEU 216 216 216 LEU LEU J . n +J 1 217 MET 217 217 217 MET MET J . n +J 1 218 SER 218 218 218 SER SER J . n +J 1 219 ALA 219 219 219 ALA ALA J . n +J 1 220 ILE 220 220 220 ILE ILE J . n +J 1 221 GLU 221 221 221 GLU GLU J . n +J 1 222 THR 222 222 222 THR THR J . n +J 1 223 GLY 223 223 223 GLY GLY J . n +J 1 224 VAL 224 224 224 VAL VAL J . n +J 1 225 ILE 225 225 225 ILE ILE J . n +J 1 226 PHE 226 226 226 PHE PHE J . n +J 1 227 LEU 227 227 227 LEU LEU J . n +J 1 228 ILE 228 228 228 ILE ILE J . n +J 1 229 ASN 229 229 229 ASN ASN J . n +J 1 230 ASP 230 230 230 ASP ASP J . n +J 1 231 GLY 231 231 231 GLY GLY J . n +J 1 232 ILE 232 232 232 ILE ILE J . n +J 1 233 ASP 233 233 233 ASP ASP J . n +J 1 234 ARG 234 234 234 ARG ARG J . n +J 1 235 GLY 235 235 235 GLY GLY J . n +J 1 236 LEU 236 236 236 LEU LEU J . n +J 1 237 TRP 237 237 237 TRP TRP J . n +J 1 238 ASP 238 238 238 ASP ASP J . n +J 1 239 LEU 239 239 239 LEU LEU J . n +J 1 240 GLN 240 240 240 GLN GLN J . n +J 1 241 ASN 241 241 241 ASN ASN J . n +J 1 242 LYS 242 242 242 LYS LYS J . n +J 1 243 ALA 243 243 243 ALA ALA J . n +J 1 244 GLU 244 244 244 GLU GLU J . n +J 1 245 ARG 245 245 245 ARG ARG J . n +J 1 246 GLN 246 246 246 GLN GLN J . n +J 1 247 ASN 247 247 247 ASN ASN J . n +J 1 248 ASP 248 248 248 ASP ASP J . n +J 1 249 ILE 249 249 249 ILE ILE J . n +J 1 250 LEU 250 250 250 LEU LEU J . n +J 1 251 VAL 251 251 251 VAL VAL J . n +J 1 252 LYS 252 252 252 LYS LYS J . n +J 1 253 TYR 253 253 253 TYR TYR J . n +J 1 254 ARG 254 254 254 ARG ARG J . n +J 1 255 HIS 255 255 255 HIS HIS J . n +J 1 256 MET 256 256 256 MET MET J . n +J 1 257 SER 257 257 257 SER SER J . n +J 1 258 VAL 258 258 ? ? ? J . n +J 1 259 PRO 259 259 ? ? ? J . n +J 1 260 PRO 260 260 ? ? ? J . n +J 1 261 GLU 261 261 ? ? ? J . n +J 1 262 SER 262 262 ? ? ? J . n +K 1 1 CYS 1 1 ? ? ? K . n +K 1 2 LEU 2 2 2 LEU LEU K . n +K 1 3 THR 3 3 3 THR THR K . n +K 1 4 ALA 4 4 4 ALA ALA K . n +K 1 5 PRO 5 5 5 PRO PRO K . n +K 1 6 PRO 6 6 6 PRO PRO K . n +K 1 7 LYS 7 7 7 LYS LYS K . n +K 1 8 GLU 8 8 8 GLU GLU K . n +K 1 9 ALA 9 9 9 ALA ALA K . n +K 1 10 ALA 10 10 10 ALA ALA K . n +K 1 11 ARG 11 11 11 ARG ARG K . n +K 1 12 PRO 12 12 12 PRO PRO K . n +K 1 13 THR 13 13 13 THR THR K . n +K 1 14 LEU 14 14 14 LEU LEU K . n +K 1 15 MET 15 15 15 MET MET K . n +K 1 16 PRO 16 16 16 PRO PRO K . n +K 1 17 ARG 17 17 17 ARG ARG K . n +K 1 18 ALA 18 18 18 ALA ALA K . n +K 1 19 GLN 19 19 19 GLN GLN K . n +K 1 20 SER 20 20 20 SER SER K . n +K 1 21 TYR 21 21 21 TYR TYR K . n +K 1 22 LYS 22 22 22 LYS LYS K . n +K 1 23 ASP 23 23 23 ASP ASP K . n +K 1 24 LEU 24 24 24 LEU LEU K . n +K 1 25 THR 25 25 25 THR THR K . n +K 1 26 HIS 26 26 26 HIS HIS K . n +K 1 27 LEU 27 27 27 LEU LEU K . n +K 1 28 PRO 28 28 28 PRO PRO K . n +K 1 29 ALA 29 29 29 ALA ALA K . n +K 1 30 PRO 30 30 30 PRO PRO K . n +K 1 31 THR 31 31 31 THR THR K . n +K 1 32 GLY 32 32 32 GLY GLY K . n +K 1 33 LYS 33 33 33 LYS LYS K . n +K 1 34 ILE 34 34 34 ILE ILE K . n +K 1 35 PHE 35 35 35 PHE PHE K . n +K 1 36 VAL 36 36 36 VAL VAL K . n +K 1 37 SER 37 37 37 SER SER K . n +K 1 38 VAL 38 38 38 VAL VAL K . n +K 1 39 TYR 39 39 39 TYR TYR K . n +K 1 40 ASN 40 40 40 ASN ASN K . n +K 1 41 ILE 41 41 41 ILE ILE K . n +K 1 42 GLN 42 42 42 GLN GLN K . n +K 1 43 ASP 43 43 43 ASP ASP K . n +K 1 44 GLU 44 44 44 GLU GLU K . n +K 1 45 THR 45 45 45 THR THR K . n +K 1 46 GLY 46 46 46 GLY GLY K . n +K 1 47 GLN 47 47 47 GLN GLN K . n +K 1 48 PHE 48 48 48 PHE PHE K . n +K 1 49 LYS 49 49 49 LYS LYS K . n +K 1 50 PRO 50 50 50 PRO PRO K . n +K 1 51 TYR 51 51 51 TYR TYR K . n +K 1 52 PRO 52 52 52 PRO PRO K . n +K 1 53 ALA 53 53 53 ALA ALA K . n +K 1 54 SER 54 54 54 SER SER K . n +K 1 55 ASN 55 55 55 ASN ASN K . n +K 1 56 PHE 56 56 56 PHE PHE K . n +K 1 57 SER 57 57 57 SER SER K . n +K 1 58 THR 58 58 58 THR THR K . n +K 1 59 ALA 59 59 59 ALA ALA K . n +K 1 60 VAL 60 60 60 VAL VAL K . n +K 1 61 PRO 61 61 61 PRO PRO K . n +K 1 62 GLN 62 62 62 GLN GLN K . n +K 1 63 SER 63 63 63 SER SER K . n +K 1 64 ALA 64 64 64 ALA ALA K . n +K 1 65 THR 65 65 65 THR THR K . n +K 1 66 ALA 66 66 66 ALA ALA K . n +K 1 67 MET 67 67 67 MET MET K . n +K 1 68 LEU 68 68 68 LEU LEU K . n +K 1 69 VAL 69 69 69 VAL VAL K . n +K 1 70 THR 70 70 70 THR THR K . n +K 1 71 ALA 71 71 71 ALA ALA K . n +K 1 72 LEU 72 72 72 LEU LEU K . n +K 1 73 LYS 73 73 73 LYS LYS K . n +K 1 74 ASP 74 74 74 ASP ASP K . n +K 1 75 SER 75 75 75 SER SER K . n +K 1 76 ARG 76 76 76 ARG ARG K . n +K 1 77 TRP 77 77 77 TRP TRP K . n +K 1 78 PHE 78 78 78 PHE PHE K . n +K 1 79 ILE 79 79 79 ILE ILE K . n +K 1 80 PRO 80 80 80 PRO PRO K . n +K 1 81 LEU 81 81 81 LEU LEU K . n +K 1 82 GLU 82 82 82 GLU GLU K . n +K 1 83 ARG 83 83 83 ARG ARG K . n +K 1 84 GLN 84 84 84 GLN GLN K . n +K 1 85 GLY 85 85 85 GLY GLY K . n +K 1 86 LEU 86 86 86 LEU LEU K . n +K 1 87 GLN 87 87 87 GLN GLN K . n +K 1 88 ASN 88 88 88 ASN ASN K . n +K 1 89 LEU 89 89 89 LEU LEU K . n +K 1 90 LEU 90 90 90 LEU LEU K . n +K 1 91 ASN 91 91 91 ASN ASN K . n +K 1 92 GLU 92 92 92 GLU GLU K . n +K 1 93 ARG 93 93 93 ARG ARG K . n +K 1 94 LYS 94 94 94 LYS LYS K . n +K 1 95 ILE 95 95 95 ILE ILE K . n +K 1 96 ILE 96 96 96 ILE ILE K . n +K 1 97 ARG 97 97 97 ARG ARG K . n +K 1 98 ALA 98 98 98 ALA ALA K . n +K 1 99 ALA 99 99 99 ALA ALA K . n +K 1 100 GLN 100 100 100 GLN GLN K . n +K 1 101 GLU 101 101 101 GLU GLU K . n +K 1 102 ASN 102 102 102 ASN ASN K . n +K 1 103 GLY 103 103 103 GLY GLY K . n +K 1 104 THR 104 104 104 THR THR K . n +K 1 105 VAL 105 105 105 VAL VAL K . n +K 1 106 ALA 106 106 106 ALA ALA K . n +K 1 107 ILE 107 107 107 ILE ILE K . n +K 1 108 ASN 108 108 108 ASN ASN K . n +K 1 109 ASN 109 109 109 ASN ASN K . n +K 1 110 ARG 110 110 110 ARG ARG K . n +K 1 111 ILE 111 111 111 ILE ILE K . n +K 1 112 PRO 112 112 112 PRO PRO K . n +K 1 113 LEU 113 113 113 LEU LEU K . n +K 1 114 GLN 114 114 114 GLN GLN K . n +K 1 115 SER 115 115 115 SER SER K . n +K 1 116 LEU 116 116 116 LEU LEU K . n +K 1 117 THR 117 117 117 THR THR K . n +K 1 118 ALA 118 118 118 ALA ALA K . n +K 1 119 ALA 119 119 119 ALA ALA K . n +K 1 120 ASN 120 120 120 ASN ASN K . n +K 1 121 ILE 121 121 121 ILE ILE K . n +K 1 122 MET 122 122 122 MET MET K . n +K 1 123 VAL 123 123 123 VAL VAL K . n +K 1 124 GLU 124 124 124 GLU GLU K . n +K 1 125 GLY 125 125 125 GLY GLY K . n +K 1 126 SER 126 126 126 SER SER K . n +K 1 127 ILE 127 127 127 ILE ILE K . n +K 1 128 ILE 128 128 128 ILE ILE K . n +K 1 129 GLY 129 129 129 GLY GLY K . n +K 1 130 TYR 130 130 130 TYR TYR K . n +K 1 131 GLU 131 131 131 GLU GLU K . n +K 1 132 SER 132 132 132 SER SER K . n +K 1 133 ASN 133 133 133 ASN ASN K . n +K 1 134 VAL 134 134 134 VAL VAL K . n +K 1 135 LYS 135 135 135 LYS LYS K . n +K 1 136 SER 136 136 136 SER SER K . n +K 1 137 GLY 137 137 137 GLY GLY K . n +K 1 138 GLY 138 138 138 GLY GLY K . n +K 1 139 VAL 139 139 139 VAL VAL K . n +K 1 140 GLY 140 140 140 GLY GLY K . n +K 1 141 ALA 141 141 141 ALA ALA K . n +K 1 142 ARG 142 142 142 ARG ARG K . n +K 1 143 TYR 143 143 143 TYR TYR K . n +K 1 144 PHE 144 144 ? ? ? K . n +K 1 145 GLY 145 145 145 GLY GLY K . n +K 1 146 ILE 146 146 146 ILE ILE K . n +K 1 147 GLY 147 147 147 GLY GLY K . n +K 1 148 ALA 148 148 148 ALA ALA K . n +K 1 149 ASP 149 149 149 ASP ASP K . n +K 1 150 THR 150 150 150 THR THR K . n +K 1 151 GLN 151 151 151 GLN GLN K . n +K 1 152 TYR 152 152 152 TYR TYR K . n +K 1 153 GLN 153 153 153 GLN GLN K . n +K 1 154 LEU 154 154 154 LEU LEU K . n +K 1 155 ASP 155 155 155 ASP ASP K . n +K 1 156 GLN 156 156 156 GLN GLN K . n +K 1 157 ILE 157 157 157 ILE ILE K . n +K 1 158 ALA 158 158 158 ALA ALA K . n +K 1 159 VAL 159 159 159 VAL VAL K . n +K 1 160 ASN 160 160 160 ASN ASN K . n +K 1 161 LEU 161 161 161 LEU LEU K . n +K 1 162 ARG 162 162 162 ARG ARG K . n +K 1 163 VAL 163 163 163 VAL VAL K . n +K 1 164 VAL 164 164 164 VAL VAL K . n +K 1 165 ASN 165 165 165 ASN ASN K . n +K 1 166 VAL 166 166 166 VAL VAL K . n +K 1 167 SER 167 167 167 SER SER K . n +K 1 168 THR 168 168 168 THR THR K . n +K 1 169 GLY 169 169 169 GLY GLY K . n +K 1 170 GLU 170 170 170 GLU GLU K . n +K 1 171 ILE 171 171 171 ILE ILE K . n +K 1 172 LEU 172 172 172 LEU LEU K . n +K 1 173 SER 173 173 173 SER SER K . n +K 1 174 SER 174 174 174 SER SER K . n +K 1 175 VAL 175 175 175 VAL VAL K . n +K 1 176 ASN 176 176 176 ASN ASN K . n +K 1 177 THR 177 177 177 THR THR K . n +K 1 178 SER 178 178 178 SER SER K . n +K 1 179 LYS 179 179 179 LYS LYS K . n +K 1 180 THR 180 180 180 THR THR K . n +K 1 181 ILE 181 181 181 ILE ILE K . n +K 1 182 LEU 182 182 182 LEU LEU K . n +K 1 183 SER 183 183 183 SER SER K . n +K 1 184 TYR 184 184 184 TYR TYR K . n +K 1 185 GLU 185 185 185 GLU GLU K . n +K 1 186 VAL 186 186 186 VAL VAL K . n +K 1 187 GLN 187 187 187 GLN GLN K . n +K 1 188 ALA 188 188 188 ALA ALA K . n +K 1 189 GLY 189 189 189 GLY GLY K . n +K 1 190 VAL 190 190 190 VAL VAL K . n +K 1 191 PHE 191 191 191 PHE PHE K . n +K 1 192 ARG 192 192 ? ? ? K . n +K 1 193 PHE 193 193 ? ? ? K . n +K 1 194 ILE 194 194 ? ? ? K . n +K 1 195 ASP 195 195 ? ? ? K . n +K 1 196 TYR 196 196 ? ? ? K . n +K 1 197 GLN 197 197 ? ? ? K . n +K 1 198 ARG 198 198 ? ? ? K . n +K 1 199 LEU 199 199 ? ? ? K . n +K 1 200 LEU 200 200 200 LEU LEU K . n +K 1 201 GLU 201 201 201 GLU GLU K . n +K 1 202 GLY 202 202 202 GLY GLY K . n +K 1 203 GLU 203 203 203 GLU GLU K . n +K 1 204 VAL 204 204 204 VAL VAL K . n +K 1 205 GLY 205 205 205 GLY GLY K . n +K 1 206 TYR 206 206 206 TYR TYR K . n +K 1 207 THR 207 207 207 THR THR K . n +K 1 208 SER 208 208 208 SER SER K . n +K 1 209 ASN 209 209 209 ASN ASN K . n +K 1 210 GLU 210 210 210 GLU GLU K . n +K 1 211 PRO 211 211 211 PRO PRO K . n +K 1 212 VAL 212 212 212 VAL VAL K . n +K 1 213 MET 213 213 213 MET MET K . n +K 1 214 LEU 214 214 214 LEU LEU K . n +K 1 215 CYS 215 215 215 CYS CYS K . n +K 1 216 LEU 216 216 216 LEU LEU K . n +K 1 217 MET 217 217 217 MET MET K . n +K 1 218 SER 218 218 218 SER SER K . n +K 1 219 ALA 219 219 219 ALA ALA K . n +K 1 220 ILE 220 220 220 ILE ILE K . n +K 1 221 GLU 221 221 221 GLU GLU K . n +K 1 222 THR 222 222 222 THR THR K . n +K 1 223 GLY 223 223 223 GLY GLY K . n +K 1 224 VAL 224 224 224 VAL VAL K . n +K 1 225 ILE 225 225 225 ILE ILE K . n +K 1 226 PHE 226 226 226 PHE PHE K . n +K 1 227 LEU 227 227 227 LEU LEU K . n +K 1 228 ILE 228 228 228 ILE ILE K . n +K 1 229 ASN 229 229 229 ASN ASN K . n +K 1 230 ASP 230 230 230 ASP ASP K . n +K 1 231 GLY 231 231 231 GLY GLY K . n +K 1 232 ILE 232 232 232 ILE ILE K . n +K 1 233 ASP 233 233 233 ASP ASP K . n +K 1 234 ARG 234 234 234 ARG ARG K . n +K 1 235 GLY 235 235 235 GLY GLY K . n +K 1 236 LEU 236 236 236 LEU LEU K . n +K 1 237 TRP 237 237 237 TRP TRP K . n +K 1 238 ASP 238 238 238 ASP ASP K . n +K 1 239 LEU 239 239 239 LEU LEU K . n +K 1 240 GLN 240 240 240 GLN GLN K . n +K 1 241 ASN 241 241 241 ASN ASN K . n +K 1 242 LYS 242 242 242 LYS LYS K . n +K 1 243 ALA 243 243 243 ALA ALA K . n +K 1 244 GLU 244 244 244 GLU GLU K . n +K 1 245 ARG 245 245 245 ARG ARG K . n +K 1 246 GLN 246 246 246 GLN GLN K . n +K 1 247 ASN 247 247 247 ASN ASN K . n +K 1 248 ASP 248 248 248 ASP ASP K . n +K 1 249 ILE 249 249 249 ILE ILE K . n +K 1 250 LEU 250 250 250 LEU LEU K . n +K 1 251 VAL 251 251 251 VAL VAL K . n +K 1 252 LYS 252 252 252 LYS LYS K . n +K 1 253 TYR 253 253 253 TYR TYR K . n +K 1 254 ARG 254 254 254 ARG ARG K . n +K 1 255 HIS 255 255 255 HIS HIS K . n +K 1 256 MET 256 256 256 MET MET K . n +K 1 257 SER 257 257 257 SER SER K . n +K 1 258 VAL 258 258 ? ? ? K . n +K 1 259 PRO 259 259 ? ? ? K . n +K 1 260 PRO 260 260 ? ? ? K . n +K 1 261 GLU 261 261 ? ? ? K . n +K 1 262 SER 262 262 ? ? ? K . n +L 1 1 CYS 1 1 ? ? ? L . n +L 1 2 LEU 2 2 2 LEU LEU L . n +L 1 3 THR 3 3 3 THR THR L . n +L 1 4 ALA 4 4 4 ALA ALA L . n +L 1 5 PRO 5 5 5 PRO PRO L . n +L 1 6 PRO 6 6 6 PRO PRO L . n +L 1 7 LYS 7 7 7 LYS LYS L . n +L 1 8 GLU 8 8 8 GLU GLU L . n +L 1 9 ALA 9 9 9 ALA ALA L . n +L 1 10 ALA 10 10 10 ALA ALA L . n +L 1 11 ARG 11 11 11 ARG ARG L . n +L 1 12 PRO 12 12 12 PRO PRO L . n +L 1 13 THR 13 13 13 THR THR L . n +L 1 14 LEU 14 14 14 LEU LEU L . n +L 1 15 MET 15 15 15 MET MET L . n +L 1 16 PRO 16 16 16 PRO PRO L . n +L 1 17 ARG 17 17 17 ARG ARG L . n +L 1 18 ALA 18 18 18 ALA ALA L . n +L 1 19 GLN 19 19 19 GLN GLN L . n +L 1 20 SER 20 20 20 SER SER L . n +L 1 21 TYR 21 21 21 TYR TYR L . n +L 1 22 LYS 22 22 22 LYS LYS L . n +L 1 23 ASP 23 23 23 ASP ASP L . n +L 1 24 LEU 24 24 24 LEU LEU L . n +L 1 25 THR 25 25 25 THR THR L . n +L 1 26 HIS 26 26 26 HIS HIS L . n +L 1 27 LEU 27 27 27 LEU LEU L . n +L 1 28 PRO 28 28 28 PRO PRO L . n +L 1 29 ALA 29 29 29 ALA ALA L . n +L 1 30 PRO 30 30 30 PRO PRO L . n +L 1 31 THR 31 31 31 THR THR L . n +L 1 32 GLY 32 32 32 GLY GLY L . n +L 1 33 LYS 33 33 33 LYS LYS L . n +L 1 34 ILE 34 34 34 ILE ILE L . n +L 1 35 PHE 35 35 35 PHE PHE L . n +L 1 36 VAL 36 36 36 VAL VAL L . n +L 1 37 SER 37 37 37 SER SER L . n +L 1 38 VAL 38 38 38 VAL VAL L . n +L 1 39 TYR 39 39 39 TYR TYR L . n +L 1 40 ASN 40 40 40 ASN ASN L . n +L 1 41 ILE 41 41 41 ILE ILE L . n +L 1 42 GLN 42 42 42 GLN GLN L . n +L 1 43 ASP 43 43 43 ASP ASP L . n +L 1 44 GLU 44 44 44 GLU GLU L . n +L 1 45 THR 45 45 45 THR THR L . n +L 1 46 GLY 46 46 46 GLY GLY L . n +L 1 47 GLN 47 47 47 GLN GLN L . n +L 1 48 PHE 48 48 48 PHE PHE L . n +L 1 49 LYS 49 49 49 LYS LYS L . n +L 1 50 PRO 50 50 50 PRO PRO L . n +L 1 51 TYR 51 51 51 TYR TYR L . n +L 1 52 PRO 52 52 52 PRO PRO L . n +L 1 53 ALA 53 53 53 ALA ALA L . n +L 1 54 SER 54 54 54 SER SER L . n +L 1 55 ASN 55 55 55 ASN ASN L . n +L 1 56 PHE 56 56 56 PHE PHE L . n +L 1 57 SER 57 57 57 SER SER L . n +L 1 58 THR 58 58 58 THR THR L . n +L 1 59 ALA 59 59 59 ALA ALA L . n +L 1 60 VAL 60 60 60 VAL VAL L . n +L 1 61 PRO 61 61 61 PRO PRO L . n +L 1 62 GLN 62 62 62 GLN GLN L . n +L 1 63 SER 63 63 63 SER SER L . n +L 1 64 ALA 64 64 64 ALA ALA L . n +L 1 65 THR 65 65 65 THR THR L . n +L 1 66 ALA 66 66 66 ALA ALA L . n +L 1 67 MET 67 67 67 MET MET L . n +L 1 68 LEU 68 68 68 LEU LEU L . n +L 1 69 VAL 69 69 69 VAL VAL L . n +L 1 70 THR 70 70 70 THR THR L . n +L 1 71 ALA 71 71 71 ALA ALA L . n +L 1 72 LEU 72 72 72 LEU LEU L . n +L 1 73 LYS 73 73 73 LYS LYS L . n +L 1 74 ASP 74 74 74 ASP ASP L . n +L 1 75 SER 75 75 75 SER SER L . n +L 1 76 ARG 76 76 76 ARG ARG L . n +L 1 77 TRP 77 77 77 TRP TRP L . n +L 1 78 PHE 78 78 78 PHE PHE L . n +L 1 79 ILE 79 79 79 ILE ILE L . n +L 1 80 PRO 80 80 80 PRO PRO L . n +L 1 81 LEU 81 81 81 LEU LEU L . n +L 1 82 GLU 82 82 82 GLU GLU L . n +L 1 83 ARG 83 83 83 ARG ARG L . n +L 1 84 GLN 84 84 84 GLN GLN L . n +L 1 85 GLY 85 85 85 GLY GLY L . n +L 1 86 LEU 86 86 86 LEU LEU L . n +L 1 87 GLN 87 87 87 GLN GLN L . n +L 1 88 ASN 88 88 88 ASN ASN L . n +L 1 89 LEU 89 89 89 LEU LEU L . n +L 1 90 LEU 90 90 90 LEU LEU L . n +L 1 91 ASN 91 91 91 ASN ASN L . n +L 1 92 GLU 92 92 92 GLU GLU L . n +L 1 93 ARG 93 93 93 ARG ARG L . n +L 1 94 LYS 94 94 94 LYS LYS L . n +L 1 95 ILE 95 95 95 ILE ILE L . n +L 1 96 ILE 96 96 96 ILE ILE L . n +L 1 97 ARG 97 97 97 ARG ARG L . n +L 1 98 ALA 98 98 98 ALA ALA L . n +L 1 99 ALA 99 99 99 ALA ALA L . n +L 1 100 GLN 100 100 100 GLN GLN L . n +L 1 101 GLU 101 101 101 GLU GLU L . n +L 1 102 ASN 102 102 102 ASN ASN L . n +L 1 103 GLY 103 103 103 GLY GLY L . n +L 1 104 THR 104 104 104 THR THR L . n +L 1 105 VAL 105 105 105 VAL VAL L . n +L 1 106 ALA 106 106 106 ALA ALA L . n +L 1 107 ILE 107 107 107 ILE ILE L . n +L 1 108 ASN 108 108 108 ASN ASN L . n +L 1 109 ASN 109 109 109 ASN ASN L . n +L 1 110 ARG 110 110 110 ARG ARG L . n +L 1 111 ILE 111 111 111 ILE ILE L . n +L 1 112 PRO 112 112 112 PRO PRO L . n +L 1 113 LEU 113 113 113 LEU LEU L . n +L 1 114 GLN 114 114 114 GLN GLN L . n +L 1 115 SER 115 115 115 SER SER L . n +L 1 116 LEU 116 116 116 LEU LEU L . n +L 1 117 THR 117 117 117 THR THR L . n +L 1 118 ALA 118 118 118 ALA ALA L . n +L 1 119 ALA 119 119 119 ALA ALA L . n +L 1 120 ASN 120 120 120 ASN ASN L . n +L 1 121 ILE 121 121 121 ILE ILE L . n +L 1 122 MET 122 122 122 MET MET L . n +L 1 123 VAL 123 123 123 VAL VAL L . n +L 1 124 GLU 124 124 124 GLU GLU L . n +L 1 125 GLY 125 125 125 GLY GLY L . n +L 1 126 SER 126 126 126 SER SER L . n +L 1 127 ILE 127 127 127 ILE ILE L . n +L 1 128 ILE 128 128 128 ILE ILE L . n +L 1 129 GLY 129 129 129 GLY GLY L . n +L 1 130 TYR 130 130 130 TYR TYR L . n +L 1 131 GLU 131 131 131 GLU GLU L . n +L 1 132 SER 132 132 132 SER SER L . n +L 1 133 ASN 133 133 133 ASN ASN L . n +L 1 134 VAL 134 134 134 VAL VAL L . n +L 1 135 LYS 135 135 135 LYS LYS L . n +L 1 136 SER 136 136 136 SER SER L . n +L 1 137 GLY 137 137 137 GLY GLY L . n +L 1 138 GLY 138 138 138 GLY GLY L . n +L 1 139 VAL 139 139 139 VAL VAL L . n +L 1 140 GLY 140 140 140 GLY GLY L . n +L 1 141 ALA 141 141 141 ALA ALA L . n +L 1 142 ARG 142 142 142 ARG ARG L . n +L 1 143 TYR 143 143 143 TYR TYR L . n +L 1 144 PHE 144 144 ? ? ? L . n +L 1 145 GLY 145 145 145 GLY GLY L . n +L 1 146 ILE 146 146 146 ILE ILE L . n +L 1 147 GLY 147 147 147 GLY GLY L . n +L 1 148 ALA 148 148 148 ALA ALA L . n +L 1 149 ASP 149 149 149 ASP ASP L . n +L 1 150 THR 150 150 150 THR THR L . n +L 1 151 GLN 151 151 151 GLN GLN L . n +L 1 152 TYR 152 152 152 TYR TYR L . n +L 1 153 GLN 153 153 153 GLN GLN L . n +L 1 154 LEU 154 154 154 LEU LEU L . n +L 1 155 ASP 155 155 155 ASP ASP L . n +L 1 156 GLN 156 156 156 GLN GLN L . n +L 1 157 ILE 157 157 157 ILE ILE L . n +L 1 158 ALA 158 158 158 ALA ALA L . n +L 1 159 VAL 159 159 159 VAL VAL L . n +L 1 160 ASN 160 160 160 ASN ASN L . n +L 1 161 LEU 161 161 161 LEU LEU L . n +L 1 162 ARG 162 162 162 ARG ARG L . n +L 1 163 VAL 163 163 163 VAL VAL L . n +L 1 164 VAL 164 164 164 VAL VAL L . n +L 1 165 ASN 165 165 165 ASN ASN L . n +L 1 166 VAL 166 166 166 VAL VAL L . n +L 1 167 SER 167 167 167 SER SER L . n +L 1 168 THR 168 168 168 THR THR L . n +L 1 169 GLY 169 169 169 GLY GLY L . n +L 1 170 GLU 170 170 170 GLU GLU L . n +L 1 171 ILE 171 171 171 ILE ILE L . n +L 1 172 LEU 172 172 172 LEU LEU L . n +L 1 173 SER 173 173 173 SER SER L . n +L 1 174 SER 174 174 174 SER SER L . n +L 1 175 VAL 175 175 175 VAL VAL L . n +L 1 176 ASN 176 176 176 ASN ASN L . n +L 1 177 THR 177 177 177 THR THR L . n +L 1 178 SER 178 178 178 SER SER L . n +L 1 179 LYS 179 179 179 LYS LYS L . n +L 1 180 THR 180 180 180 THR THR L . n +L 1 181 ILE 181 181 181 ILE ILE L . n +L 1 182 LEU 182 182 182 LEU LEU L . n +L 1 183 SER 183 183 183 SER SER L . n +L 1 184 TYR 184 184 184 TYR TYR L . n +L 1 185 GLU 185 185 185 GLU GLU L . n +L 1 186 VAL 186 186 186 VAL VAL L . n +L 1 187 GLN 187 187 187 GLN GLN L . n +L 1 188 ALA 188 188 188 ALA ALA L . n +L 1 189 GLY 189 189 189 GLY GLY L . n +L 1 190 VAL 190 190 190 VAL VAL L . n +L 1 191 PHE 191 191 191 PHE PHE L . n +L 1 192 ARG 192 192 ? ? ? L . n +L 1 193 PHE 193 193 ? ? ? L . n +L 1 194 ILE 194 194 ? ? ? L . n +L 1 195 ASP 195 195 ? ? ? L . n +L 1 196 TYR 196 196 ? ? ? L . n +L 1 197 GLN 197 197 ? ? ? L . n +L 1 198 ARG 198 198 ? ? ? L . n +L 1 199 LEU 199 199 ? ? ? L . n +L 1 200 LEU 200 200 200 LEU LEU L . n +L 1 201 GLU 201 201 201 GLU GLU L . n +L 1 202 GLY 202 202 202 GLY GLY L . n +L 1 203 GLU 203 203 203 GLU GLU L . n +L 1 204 VAL 204 204 204 VAL VAL L . n +L 1 205 GLY 205 205 205 GLY GLY L . n +L 1 206 TYR 206 206 206 TYR TYR L . n +L 1 207 THR 207 207 207 THR THR L . n +L 1 208 SER 208 208 208 SER SER L . n +L 1 209 ASN 209 209 209 ASN ASN L . n +L 1 210 GLU 210 210 210 GLU GLU L . n +L 1 211 PRO 211 211 211 PRO PRO L . n +L 1 212 VAL 212 212 212 VAL VAL L . n +L 1 213 MET 213 213 213 MET MET L . n +L 1 214 LEU 214 214 214 LEU LEU L . n +L 1 215 CYS 215 215 215 CYS CYS L . n +L 1 216 LEU 216 216 216 LEU LEU L . n +L 1 217 MET 217 217 217 MET MET L . n +L 1 218 SER 218 218 218 SER SER L . n +L 1 219 ALA 219 219 219 ALA ALA L . n +L 1 220 ILE 220 220 220 ILE ILE L . n +L 1 221 GLU 221 221 221 GLU GLU L . n +L 1 222 THR 222 222 222 THR THR L . n +L 1 223 GLY 223 223 223 GLY GLY L . n +L 1 224 VAL 224 224 224 VAL VAL L . n +L 1 225 ILE 225 225 225 ILE ILE L . n +L 1 226 PHE 226 226 226 PHE PHE L . n +L 1 227 LEU 227 227 227 LEU LEU L . n +L 1 228 ILE 228 228 228 ILE ILE L . n +L 1 229 ASN 229 229 229 ASN ASN L . n +L 1 230 ASP 230 230 230 ASP ASP L . n +L 1 231 GLY 231 231 231 GLY GLY L . n +L 1 232 ILE 232 232 232 ILE ILE L . n +L 1 233 ASP 233 233 233 ASP ASP L . n +L 1 234 ARG 234 234 234 ARG ARG L . n +L 1 235 GLY 235 235 235 GLY GLY L . n +L 1 236 LEU 236 236 236 LEU LEU L . n +L 1 237 TRP 237 237 237 TRP TRP L . n +L 1 238 ASP 238 238 238 ASP ASP L . n +L 1 239 LEU 239 239 239 LEU LEU L . n +L 1 240 GLN 240 240 240 GLN GLN L . n +L 1 241 ASN 241 241 241 ASN ASN L . n +L 1 242 LYS 242 242 242 LYS LYS L . n +L 1 243 ALA 243 243 243 ALA ALA L . n +L 1 244 GLU 244 244 244 GLU GLU L . n +L 1 245 ARG 245 245 245 ARG ARG L . n +L 1 246 GLN 246 246 246 GLN GLN L . n +L 1 247 ASN 247 247 247 ASN ASN L . n +L 1 248 ASP 248 248 248 ASP ASP L . n +L 1 249 ILE 249 249 249 ILE ILE L . n +L 1 250 LEU 250 250 250 LEU LEU L . n +L 1 251 VAL 251 251 251 VAL VAL L . n +L 1 252 LYS 252 252 252 LYS LYS L . n +L 1 253 TYR 253 253 253 TYR TYR L . n +L 1 254 ARG 254 254 254 ARG ARG L . n +L 1 255 HIS 255 255 255 HIS HIS L . n +L 1 256 MET 256 256 256 MET MET L . n +L 1 257 SER 257 257 257 SER SER L . n +L 1 258 VAL 258 258 ? ? ? L . n +L 1 259 PRO 259 259 ? ? ? L . n +L 1 260 PRO 260 260 ? ? ? L . n +L 1 261 GLU 261 261 ? ? ? L . n +L 1 262 SER 262 262 ? ? ? L . n +M 1 1 CYS 1 1 ? ? ? M . n +M 1 2 LEU 2 2 2 LEU LEU M . n +M 1 3 THR 3 3 3 THR THR M . n +M 1 4 ALA 4 4 4 ALA ALA M . n +M 1 5 PRO 5 5 5 PRO PRO M . n +M 1 6 PRO 6 6 6 PRO PRO M . n +M 1 7 LYS 7 7 7 LYS LYS M . n +M 1 8 GLU 8 8 8 GLU GLU M . n +M 1 9 ALA 9 9 9 ALA ALA M . n +M 1 10 ALA 10 10 10 ALA ALA M . n +M 1 11 ARG 11 11 11 ARG ARG M . n +M 1 12 PRO 12 12 12 PRO PRO M . n +M 1 13 THR 13 13 13 THR THR M . n +M 1 14 LEU 14 14 14 LEU LEU M . n +M 1 15 MET 15 15 15 MET MET M . n +M 1 16 PRO 16 16 16 PRO PRO M . n +M 1 17 ARG 17 17 17 ARG ARG M . n +M 1 18 ALA 18 18 18 ALA ALA M . n +M 1 19 GLN 19 19 19 GLN GLN M . n +M 1 20 SER 20 20 20 SER SER M . n +M 1 21 TYR 21 21 21 TYR TYR M . n +M 1 22 LYS 22 22 22 LYS LYS M . n +M 1 23 ASP 23 23 23 ASP ASP M . n +M 1 24 LEU 24 24 24 LEU LEU M . n +M 1 25 THR 25 25 25 THR THR M . n +M 1 26 HIS 26 26 26 HIS HIS M . n +M 1 27 LEU 27 27 27 LEU LEU M . n +M 1 28 PRO 28 28 28 PRO PRO M . n +M 1 29 ALA 29 29 29 ALA ALA M . n +M 1 30 PRO 30 30 30 PRO PRO M . n +M 1 31 THR 31 31 31 THR THR M . n +M 1 32 GLY 32 32 32 GLY GLY M . n +M 1 33 LYS 33 33 33 LYS LYS M . n +M 1 34 ILE 34 34 34 ILE ILE M . n +M 1 35 PHE 35 35 35 PHE PHE M . n +M 1 36 VAL 36 36 36 VAL VAL M . n +M 1 37 SER 37 37 37 SER SER M . n +M 1 38 VAL 38 38 38 VAL VAL M . n +M 1 39 TYR 39 39 39 TYR TYR M . n +M 1 40 ASN 40 40 40 ASN ASN M . n +M 1 41 ILE 41 41 41 ILE ILE M . n +M 1 42 GLN 42 42 42 GLN GLN M . n +M 1 43 ASP 43 43 43 ASP ASP M . n +M 1 44 GLU 44 44 44 GLU GLU M . n +M 1 45 THR 45 45 45 THR THR M . n +M 1 46 GLY 46 46 46 GLY GLY M . n +M 1 47 GLN 47 47 47 GLN GLN M . n +M 1 48 PHE 48 48 48 PHE PHE M . n +M 1 49 LYS 49 49 49 LYS LYS M . n +M 1 50 PRO 50 50 50 PRO PRO M . n +M 1 51 TYR 51 51 51 TYR TYR M . n +M 1 52 PRO 52 52 52 PRO PRO M . n +M 1 53 ALA 53 53 53 ALA ALA M . n +M 1 54 SER 54 54 54 SER SER M . n +M 1 55 ASN 55 55 55 ASN ASN M . n +M 1 56 PHE 56 56 56 PHE PHE M . n +M 1 57 SER 57 57 57 SER SER M . n +M 1 58 THR 58 58 58 THR THR M . n +M 1 59 ALA 59 59 59 ALA ALA M . n +M 1 60 VAL 60 60 60 VAL VAL M . n +M 1 61 PRO 61 61 61 PRO PRO M . n +M 1 62 GLN 62 62 62 GLN GLN M . n +M 1 63 SER 63 63 63 SER SER M . n +M 1 64 ALA 64 64 64 ALA ALA M . n +M 1 65 THR 65 65 65 THR THR M . n +M 1 66 ALA 66 66 66 ALA ALA M . n +M 1 67 MET 67 67 67 MET MET M . n +M 1 68 LEU 68 68 68 LEU LEU M . n +M 1 69 VAL 69 69 69 VAL VAL M . n +M 1 70 THR 70 70 70 THR THR M . n +M 1 71 ALA 71 71 71 ALA ALA M . n +M 1 72 LEU 72 72 72 LEU LEU M . n +M 1 73 LYS 73 73 73 LYS LYS M . n +M 1 74 ASP 74 74 74 ASP ASP M . n +M 1 75 SER 75 75 75 SER SER M . n +M 1 76 ARG 76 76 76 ARG ARG M . n +M 1 77 TRP 77 77 77 TRP TRP M . n +M 1 78 PHE 78 78 78 PHE PHE M . n +M 1 79 ILE 79 79 79 ILE ILE M . n +M 1 80 PRO 80 80 80 PRO PRO M . n +M 1 81 LEU 81 81 81 LEU LEU M . n +M 1 82 GLU 82 82 82 GLU GLU M . n +M 1 83 ARG 83 83 83 ARG ARG M . n +M 1 84 GLN 84 84 84 GLN GLN M . n +M 1 85 GLY 85 85 85 GLY GLY M . n +M 1 86 LEU 86 86 86 LEU LEU M . n +M 1 87 GLN 87 87 87 GLN GLN M . n +M 1 88 ASN 88 88 88 ASN ASN M . n +M 1 89 LEU 89 89 89 LEU LEU M . n +M 1 90 LEU 90 90 90 LEU LEU M . n +M 1 91 ASN 91 91 91 ASN ASN M . n +M 1 92 GLU 92 92 92 GLU GLU M . n +M 1 93 ARG 93 93 93 ARG ARG M . n +M 1 94 LYS 94 94 94 LYS LYS M . n +M 1 95 ILE 95 95 95 ILE ILE M . n +M 1 96 ILE 96 96 96 ILE ILE M . n +M 1 97 ARG 97 97 97 ARG ARG M . n +M 1 98 ALA 98 98 98 ALA ALA M . n +M 1 99 ALA 99 99 99 ALA ALA M . n +M 1 100 GLN 100 100 100 GLN GLN M . n +M 1 101 GLU 101 101 101 GLU GLU M . n +M 1 102 ASN 102 102 102 ASN ASN M . n +M 1 103 GLY 103 103 103 GLY GLY M . n +M 1 104 THR 104 104 104 THR THR M . n +M 1 105 VAL 105 105 105 VAL VAL M . n +M 1 106 ALA 106 106 106 ALA ALA M . n +M 1 107 ILE 107 107 107 ILE ILE M . n +M 1 108 ASN 108 108 108 ASN ASN M . n +M 1 109 ASN 109 109 109 ASN ASN M . n +M 1 110 ARG 110 110 110 ARG ARG M . n +M 1 111 ILE 111 111 111 ILE ILE M . n +M 1 112 PRO 112 112 112 PRO PRO M . n +M 1 113 LEU 113 113 113 LEU LEU M . n +M 1 114 GLN 114 114 114 GLN GLN M . n +M 1 115 SER 115 115 115 SER SER M . n +M 1 116 LEU 116 116 116 LEU LEU M . n +M 1 117 THR 117 117 117 THR THR M . n +M 1 118 ALA 118 118 118 ALA ALA M . n +M 1 119 ALA 119 119 119 ALA ALA M . n +M 1 120 ASN 120 120 120 ASN ASN M . n +M 1 121 ILE 121 121 121 ILE ILE M . n +M 1 122 MET 122 122 122 MET MET M . n +M 1 123 VAL 123 123 123 VAL VAL M . n +M 1 124 GLU 124 124 124 GLU GLU M . n +M 1 125 GLY 125 125 125 GLY GLY M . n +M 1 126 SER 126 126 126 SER SER M . n +M 1 127 ILE 127 127 127 ILE ILE M . n +M 1 128 ILE 128 128 128 ILE ILE M . n +M 1 129 GLY 129 129 129 GLY GLY M . n +M 1 130 TYR 130 130 130 TYR TYR M . n +M 1 131 GLU 131 131 131 GLU GLU M . n +M 1 132 SER 132 132 132 SER SER M . n +M 1 133 ASN 133 133 133 ASN ASN M . n +M 1 134 VAL 134 134 134 VAL VAL M . n +M 1 135 LYS 135 135 135 LYS LYS M . n +M 1 136 SER 136 136 136 SER SER M . n +M 1 137 GLY 137 137 137 GLY GLY M . n +M 1 138 GLY 138 138 138 GLY GLY M . n +M 1 139 VAL 139 139 139 VAL VAL M . n +M 1 140 GLY 140 140 140 GLY GLY M . n +M 1 141 ALA 141 141 141 ALA ALA M . n +M 1 142 ARG 142 142 142 ARG ARG M . n +M 1 143 TYR 143 143 143 TYR TYR M . n +M 1 144 PHE 144 144 ? ? ? M . n +M 1 145 GLY 145 145 145 GLY GLY M . n +M 1 146 ILE 146 146 146 ILE ILE M . n +M 1 147 GLY 147 147 147 GLY GLY M . n +M 1 148 ALA 148 148 148 ALA ALA M . n +M 1 149 ASP 149 149 149 ASP ASP M . n +M 1 150 THR 150 150 150 THR THR M . n +M 1 151 GLN 151 151 151 GLN GLN M . n +M 1 152 TYR 152 152 152 TYR TYR M . n +M 1 153 GLN 153 153 153 GLN GLN M . n +M 1 154 LEU 154 154 154 LEU LEU M . n +M 1 155 ASP 155 155 155 ASP ASP M . n +M 1 156 GLN 156 156 156 GLN GLN M . n +M 1 157 ILE 157 157 157 ILE ILE M . n +M 1 158 ALA 158 158 158 ALA ALA M . n +M 1 159 VAL 159 159 159 VAL VAL M . n +M 1 160 ASN 160 160 160 ASN ASN M . n +M 1 161 LEU 161 161 161 LEU LEU M . n +M 1 162 ARG 162 162 162 ARG ARG M . n +M 1 163 VAL 163 163 163 VAL VAL M . n +M 1 164 VAL 164 164 164 VAL VAL M . n +M 1 165 ASN 165 165 165 ASN ASN M . n +M 1 166 VAL 166 166 166 VAL VAL M . n +M 1 167 SER 167 167 167 SER SER M . n +M 1 168 THR 168 168 168 THR THR M . n +M 1 169 GLY 169 169 169 GLY GLY M . n +M 1 170 GLU 170 170 170 GLU GLU M . n +M 1 171 ILE 171 171 171 ILE ILE M . n +M 1 172 LEU 172 172 172 LEU LEU M . n +M 1 173 SER 173 173 173 SER SER M . n +M 1 174 SER 174 174 174 SER SER M . n +M 1 175 VAL 175 175 175 VAL VAL M . n +M 1 176 ASN 176 176 176 ASN ASN M . n +M 1 177 THR 177 177 177 THR THR M . n +M 1 178 SER 178 178 178 SER SER M . n +M 1 179 LYS 179 179 179 LYS LYS M . n +M 1 180 THR 180 180 180 THR THR M . n +M 1 181 ILE 181 181 181 ILE ILE M . n +M 1 182 LEU 182 182 182 LEU LEU M . n +M 1 183 SER 183 183 183 SER SER M . n +M 1 184 TYR 184 184 184 TYR TYR M . n +M 1 185 GLU 185 185 185 GLU GLU M . n +M 1 186 VAL 186 186 186 VAL VAL M . n +M 1 187 GLN 187 187 187 GLN GLN M . n +M 1 188 ALA 188 188 188 ALA ALA M . n +M 1 189 GLY 189 189 189 GLY GLY M . n +M 1 190 VAL 190 190 190 VAL VAL M . n +M 1 191 PHE 191 191 191 PHE PHE M . n +M 1 192 ARG 192 192 ? ? ? M . n +M 1 193 PHE 193 193 ? ? ? M . n +M 1 194 ILE 194 194 ? ? ? M . n +M 1 195 ASP 195 195 ? ? ? M . n +M 1 196 TYR 196 196 ? ? ? M . n +M 1 197 GLN 197 197 ? ? ? M . n +M 1 198 ARG 198 198 ? ? ? M . n +M 1 199 LEU 199 199 ? ? ? M . n +M 1 200 LEU 200 200 200 LEU LEU M . n +M 1 201 GLU 201 201 201 GLU GLU M . n +M 1 202 GLY 202 202 202 GLY GLY M . n +M 1 203 GLU 203 203 203 GLU GLU M . n +M 1 204 VAL 204 204 204 VAL VAL M . n +M 1 205 GLY 205 205 205 GLY GLY M . n +M 1 206 TYR 206 206 206 TYR TYR M . n +M 1 207 THR 207 207 207 THR THR M . n +M 1 208 SER 208 208 208 SER SER M . n +M 1 209 ASN 209 209 209 ASN ASN M . n +M 1 210 GLU 210 210 210 GLU GLU M . n +M 1 211 PRO 211 211 211 PRO PRO M . n +M 1 212 VAL 212 212 212 VAL VAL M . n +M 1 213 MET 213 213 213 MET MET M . n +M 1 214 LEU 214 214 214 LEU LEU M . n +M 1 215 CYS 215 215 215 CYS CYS M . n +M 1 216 LEU 216 216 216 LEU LEU M . n +M 1 217 MET 217 217 217 MET MET M . n +M 1 218 SER 218 218 218 SER SER M . n +M 1 219 ALA 219 219 219 ALA ALA M . n +M 1 220 ILE 220 220 220 ILE ILE M . n +M 1 221 GLU 221 221 221 GLU GLU M . n +M 1 222 THR 222 222 222 THR THR M . n +M 1 223 GLY 223 223 223 GLY GLY M . n +M 1 224 VAL 224 224 224 VAL VAL M . n +M 1 225 ILE 225 225 225 ILE ILE M . n +M 1 226 PHE 226 226 226 PHE PHE M . n +M 1 227 LEU 227 227 227 LEU LEU M . n +M 1 228 ILE 228 228 228 ILE ILE M . n +M 1 229 ASN 229 229 229 ASN ASN M . n +M 1 230 ASP 230 230 230 ASP ASP M . n +M 1 231 GLY 231 231 231 GLY GLY M . n +M 1 232 ILE 232 232 232 ILE ILE M . n +M 1 233 ASP 233 233 233 ASP ASP M . n +M 1 234 ARG 234 234 234 ARG ARG M . n +M 1 235 GLY 235 235 235 GLY GLY M . n +M 1 236 LEU 236 236 236 LEU LEU M . n +M 1 237 TRP 237 237 237 TRP TRP M . n +M 1 238 ASP 238 238 238 ASP ASP M . n +M 1 239 LEU 239 239 239 LEU LEU M . n +M 1 240 GLN 240 240 240 GLN GLN M . n +M 1 241 ASN 241 241 241 ASN ASN M . n +M 1 242 LYS 242 242 242 LYS LYS M . n +M 1 243 ALA 243 243 243 ALA ALA M . n +M 1 244 GLU 244 244 244 GLU GLU M . n +M 1 245 ARG 245 245 245 ARG ARG M . n +M 1 246 GLN 246 246 246 GLN GLN M . n +M 1 247 ASN 247 247 247 ASN ASN M . n +M 1 248 ASP 248 248 248 ASP ASP M . n +M 1 249 ILE 249 249 249 ILE ILE M . n +M 1 250 LEU 250 250 250 LEU LEU M . n +M 1 251 VAL 251 251 251 VAL VAL M . n +M 1 252 LYS 252 252 252 LYS LYS M . n +M 1 253 TYR 253 253 253 TYR TYR M . n +M 1 254 ARG 254 254 254 ARG ARG M . n +M 1 255 HIS 255 255 255 HIS HIS M . n +M 1 256 MET 256 256 256 MET MET M . n +M 1 257 SER 257 257 257 SER SER M . n +M 1 258 VAL 258 258 ? ? ? M . n +M 1 259 PRO 259 259 ? ? ? M . n +M 1 260 PRO 260 260 ? ? ? M . n +M 1 261 GLU 261 261 ? ? ? M . n +M 1 262 SER 262 262 ? ? ? M . n +N 1 1 CYS 1 1 ? ? ? N . n +N 1 2 LEU 2 2 2 LEU LEU N . n +N 1 3 THR 3 3 3 THR THR N . n +N 1 4 ALA 4 4 4 ALA ALA N . n +N 1 5 PRO 5 5 5 PRO PRO N . n +N 1 6 PRO 6 6 6 PRO PRO N . n +N 1 7 LYS 7 7 7 LYS LYS N . n +N 1 8 GLU 8 8 8 GLU GLU N . n +N 1 9 ALA 9 9 9 ALA ALA N . n +N 1 10 ALA 10 10 10 ALA ALA N . n +N 1 11 ARG 11 11 11 ARG ARG N . n +N 1 12 PRO 12 12 12 PRO PRO N . n +N 1 13 THR 13 13 13 THR THR N . n +N 1 14 LEU 14 14 14 LEU LEU N . n +N 1 15 MET 15 15 15 MET MET N . n +N 1 16 PRO 16 16 16 PRO PRO N . n +N 1 17 ARG 17 17 17 ARG ARG N . n +N 1 18 ALA 18 18 18 ALA ALA N . n +N 1 19 GLN 19 19 19 GLN GLN N . n +N 1 20 SER 20 20 20 SER SER N . n +N 1 21 TYR 21 21 21 TYR TYR N . n +N 1 22 LYS 22 22 22 LYS LYS N . n +N 1 23 ASP 23 23 23 ASP ASP N . n +N 1 24 LEU 24 24 24 LEU LEU N . n +N 1 25 THR 25 25 25 THR THR N . n +N 1 26 HIS 26 26 26 HIS HIS N . n +N 1 27 LEU 27 27 27 LEU LEU N . n +N 1 28 PRO 28 28 28 PRO PRO N . n +N 1 29 ALA 29 29 29 ALA ALA N . n +N 1 30 PRO 30 30 30 PRO PRO N . n +N 1 31 THR 31 31 31 THR THR N . n +N 1 32 GLY 32 32 32 GLY GLY N . n +N 1 33 LYS 33 33 33 LYS LYS N . n +N 1 34 ILE 34 34 34 ILE ILE N . n +N 1 35 PHE 35 35 35 PHE PHE N . n +N 1 36 VAL 36 36 36 VAL VAL N . n +N 1 37 SER 37 37 37 SER SER N . n +N 1 38 VAL 38 38 38 VAL VAL N . n +N 1 39 TYR 39 39 39 TYR TYR N . n +N 1 40 ASN 40 40 40 ASN ASN N . n +N 1 41 ILE 41 41 41 ILE ILE N . n +N 1 42 GLN 42 42 42 GLN GLN N . n +N 1 43 ASP 43 43 43 ASP ASP N . n +N 1 44 GLU 44 44 44 GLU GLU N . n +N 1 45 THR 45 45 45 THR THR N . n +N 1 46 GLY 46 46 46 GLY GLY N . n +N 1 47 GLN 47 47 47 GLN GLN N . n +N 1 48 PHE 48 48 48 PHE PHE N . n +N 1 49 LYS 49 49 49 LYS LYS N . n +N 1 50 PRO 50 50 50 PRO PRO N . n +N 1 51 TYR 51 51 51 TYR TYR N . n +N 1 52 PRO 52 52 52 PRO PRO N . n +N 1 53 ALA 53 53 53 ALA ALA N . n +N 1 54 SER 54 54 54 SER SER N . n +N 1 55 ASN 55 55 55 ASN ASN N . n +N 1 56 PHE 56 56 56 PHE PHE N . n +N 1 57 SER 57 57 57 SER SER N . n +N 1 58 THR 58 58 58 THR THR N . n +N 1 59 ALA 59 59 59 ALA ALA N . n +N 1 60 VAL 60 60 60 VAL VAL N . n +N 1 61 PRO 61 61 61 PRO PRO N . n +N 1 62 GLN 62 62 62 GLN GLN N . n +N 1 63 SER 63 63 63 SER SER N . n +N 1 64 ALA 64 64 64 ALA ALA N . n +N 1 65 THR 65 65 65 THR THR N . n +N 1 66 ALA 66 66 66 ALA ALA N . n +N 1 67 MET 67 67 67 MET MET N . n +N 1 68 LEU 68 68 68 LEU LEU N . n +N 1 69 VAL 69 69 69 VAL VAL N . n +N 1 70 THR 70 70 70 THR THR N . n +N 1 71 ALA 71 71 71 ALA ALA N . n +N 1 72 LEU 72 72 72 LEU LEU N . n +N 1 73 LYS 73 73 73 LYS LYS N . n +N 1 74 ASP 74 74 74 ASP ASP N . n +N 1 75 SER 75 75 75 SER SER N . n +N 1 76 ARG 76 76 76 ARG ARG N . n +N 1 77 TRP 77 77 77 TRP TRP N . n +N 1 78 PHE 78 78 78 PHE PHE N . n +N 1 79 ILE 79 79 79 ILE ILE N . n +N 1 80 PRO 80 80 80 PRO PRO N . n +N 1 81 LEU 81 81 81 LEU LEU N . n +N 1 82 GLU 82 82 82 GLU GLU N . n +N 1 83 ARG 83 83 83 ARG ARG N . n +N 1 84 GLN 84 84 84 GLN GLN N . n +N 1 85 GLY 85 85 85 GLY GLY N . n +N 1 86 LEU 86 86 86 LEU LEU N . n +N 1 87 GLN 87 87 87 GLN GLN N . n +N 1 88 ASN 88 88 88 ASN ASN N . n +N 1 89 LEU 89 89 89 LEU LEU N . n +N 1 90 LEU 90 90 90 LEU LEU N . n +N 1 91 ASN 91 91 91 ASN ASN N . n +N 1 92 GLU 92 92 92 GLU GLU N . n +N 1 93 ARG 93 93 93 ARG ARG N . n +N 1 94 LYS 94 94 94 LYS LYS N . n +N 1 95 ILE 95 95 95 ILE ILE N . n +N 1 96 ILE 96 96 96 ILE ILE N . n +N 1 97 ARG 97 97 97 ARG ARG N . n +N 1 98 ALA 98 98 98 ALA ALA N . n +N 1 99 ALA 99 99 99 ALA ALA N . n +N 1 100 GLN 100 100 100 GLN GLN N . n +N 1 101 GLU 101 101 101 GLU GLU N . n +N 1 102 ASN 102 102 102 ASN ASN N . n +N 1 103 GLY 103 103 103 GLY GLY N . n +N 1 104 THR 104 104 104 THR THR N . n +N 1 105 VAL 105 105 105 VAL VAL N . n +N 1 106 ALA 106 106 106 ALA ALA N . n +N 1 107 ILE 107 107 107 ILE ILE N . n +N 1 108 ASN 108 108 108 ASN ASN N . n +N 1 109 ASN 109 109 109 ASN ASN N . n +N 1 110 ARG 110 110 110 ARG ARG N . n +N 1 111 ILE 111 111 111 ILE ILE N . n +N 1 112 PRO 112 112 112 PRO PRO N . n +N 1 113 LEU 113 113 113 LEU LEU N . n +N 1 114 GLN 114 114 114 GLN GLN N . n +N 1 115 SER 115 115 115 SER SER N . n +N 1 116 LEU 116 116 116 LEU LEU N . n +N 1 117 THR 117 117 117 THR THR N . n +N 1 118 ALA 118 118 118 ALA ALA N . n +N 1 119 ALA 119 119 119 ALA ALA N . n +N 1 120 ASN 120 120 120 ASN ASN N . n +N 1 121 ILE 121 121 121 ILE ILE N . n +N 1 122 MET 122 122 122 MET MET N . n +N 1 123 VAL 123 123 123 VAL VAL N . n +N 1 124 GLU 124 124 124 GLU GLU N . n +N 1 125 GLY 125 125 125 GLY GLY N . n +N 1 126 SER 126 126 126 SER SER N . n +N 1 127 ILE 127 127 127 ILE ILE N . n +N 1 128 ILE 128 128 128 ILE ILE N . n +N 1 129 GLY 129 129 129 GLY GLY N . n +N 1 130 TYR 130 130 130 TYR TYR N . n +N 1 131 GLU 131 131 131 GLU GLU N . n +N 1 132 SER 132 132 132 SER SER N . n +N 1 133 ASN 133 133 133 ASN ASN N . n +N 1 134 VAL 134 134 134 VAL VAL N . n +N 1 135 LYS 135 135 135 LYS LYS N . n +N 1 136 SER 136 136 136 SER SER N . n +N 1 137 GLY 137 137 137 GLY GLY N . n +N 1 138 GLY 138 138 138 GLY GLY N . n +N 1 139 VAL 139 139 139 VAL VAL N . n +N 1 140 GLY 140 140 140 GLY GLY N . n +N 1 141 ALA 141 141 141 ALA ALA N . n +N 1 142 ARG 142 142 142 ARG ARG N . n +N 1 143 TYR 143 143 143 TYR TYR N . n +N 1 144 PHE 144 144 ? ? ? N . n +N 1 145 GLY 145 145 145 GLY GLY N . n +N 1 146 ILE 146 146 146 ILE ILE N . n +N 1 147 GLY 147 147 147 GLY GLY N . n +N 1 148 ALA 148 148 148 ALA ALA N . n +N 1 149 ASP 149 149 149 ASP ASP N . n +N 1 150 THR 150 150 150 THR THR N . n +N 1 151 GLN 151 151 151 GLN GLN N . n +N 1 152 TYR 152 152 152 TYR TYR N . n +N 1 153 GLN 153 153 153 GLN GLN N . n +N 1 154 LEU 154 154 154 LEU LEU N . n +N 1 155 ASP 155 155 155 ASP ASP N . n +N 1 156 GLN 156 156 156 GLN GLN N . n +N 1 157 ILE 157 157 157 ILE ILE N . n +N 1 158 ALA 158 158 158 ALA ALA N . n +N 1 159 VAL 159 159 159 VAL VAL N . n +N 1 160 ASN 160 160 160 ASN ASN N . n +N 1 161 LEU 161 161 161 LEU LEU N . n +N 1 162 ARG 162 162 162 ARG ARG N . n +N 1 163 VAL 163 163 163 VAL VAL N . n +N 1 164 VAL 164 164 164 VAL VAL N . n +N 1 165 ASN 165 165 165 ASN ASN N . n +N 1 166 VAL 166 166 166 VAL VAL N . n +N 1 167 SER 167 167 167 SER SER N . n +N 1 168 THR 168 168 168 THR THR N . n +N 1 169 GLY 169 169 169 GLY GLY N . n +N 1 170 GLU 170 170 170 GLU GLU N . n +N 1 171 ILE 171 171 171 ILE ILE N . n +N 1 172 LEU 172 172 172 LEU LEU N . n +N 1 173 SER 173 173 173 SER SER N . n +N 1 174 SER 174 174 174 SER SER N . n +N 1 175 VAL 175 175 175 VAL VAL N . n +N 1 176 ASN 176 176 176 ASN ASN N . n +N 1 177 THR 177 177 177 THR THR N . n +N 1 178 SER 178 178 178 SER SER N . n +N 1 179 LYS 179 179 179 LYS LYS N . n +N 1 180 THR 180 180 180 THR THR N . n +N 1 181 ILE 181 181 181 ILE ILE N . n +N 1 182 LEU 182 182 182 LEU LEU N . n +N 1 183 SER 183 183 183 SER SER N . n +N 1 184 TYR 184 184 184 TYR TYR N . n +N 1 185 GLU 185 185 185 GLU GLU N . n +N 1 186 VAL 186 186 186 VAL VAL N . n +N 1 187 GLN 187 187 187 GLN GLN N . n +N 1 188 ALA 188 188 188 ALA ALA N . n +N 1 189 GLY 189 189 189 GLY GLY N . n +N 1 190 VAL 190 190 190 VAL VAL N . n +N 1 191 PHE 191 191 191 PHE PHE N . n +N 1 192 ARG 192 192 ? ? ? N . n +N 1 193 PHE 193 193 ? ? ? N . n +N 1 194 ILE 194 194 ? ? ? N . n +N 1 195 ASP 195 195 ? ? ? N . n +N 1 196 TYR 196 196 ? ? ? N . n +N 1 197 GLN 197 197 ? ? ? N . n +N 1 198 ARG 198 198 ? ? ? N . n +N 1 199 LEU 199 199 ? ? ? N . n +N 1 200 LEU 200 200 200 LEU LEU N . n +N 1 201 GLU 201 201 201 GLU GLU N . n +N 1 202 GLY 202 202 202 GLY GLY N . n +N 1 203 GLU 203 203 203 GLU GLU N . n +N 1 204 VAL 204 204 204 VAL VAL N . n +N 1 205 GLY 205 205 205 GLY GLY N . n +N 1 206 TYR 206 206 206 TYR TYR N . n +N 1 207 THR 207 207 207 THR THR N . n +N 1 208 SER 208 208 208 SER SER N . n +N 1 209 ASN 209 209 209 ASN ASN N . n +N 1 210 GLU 210 210 210 GLU GLU N . n +N 1 211 PRO 211 211 211 PRO PRO N . n +N 1 212 VAL 212 212 212 VAL VAL N . n +N 1 213 MET 213 213 213 MET MET N . n +N 1 214 LEU 214 214 214 LEU LEU N . n +N 1 215 CYS 215 215 215 CYS CYS N . n +N 1 216 LEU 216 216 216 LEU LEU N . n +N 1 217 MET 217 217 217 MET MET N . n +N 1 218 SER 218 218 218 SER SER N . n +N 1 219 ALA 219 219 219 ALA ALA N . n +N 1 220 ILE 220 220 220 ILE ILE N . n +N 1 221 GLU 221 221 221 GLU GLU N . n +N 1 222 THR 222 222 222 THR THR N . n +N 1 223 GLY 223 223 223 GLY GLY N . n +N 1 224 VAL 224 224 224 VAL VAL N . n +N 1 225 ILE 225 225 225 ILE ILE N . n +N 1 226 PHE 226 226 226 PHE PHE N . n +N 1 227 LEU 227 227 227 LEU LEU N . n +N 1 228 ILE 228 228 228 ILE ILE N . n +N 1 229 ASN 229 229 229 ASN ASN N . n +N 1 230 ASP 230 230 230 ASP ASP N . n +N 1 231 GLY 231 231 231 GLY GLY N . n +N 1 232 ILE 232 232 232 ILE ILE N . n +N 1 233 ASP 233 233 233 ASP ASP N . n +N 1 234 ARG 234 234 234 ARG ARG N . n +N 1 235 GLY 235 235 235 GLY GLY N . n +N 1 236 LEU 236 236 236 LEU LEU N . n +N 1 237 TRP 237 237 237 TRP TRP N . n +N 1 238 ASP 238 238 238 ASP ASP N . n +N 1 239 LEU 239 239 239 LEU LEU N . n +N 1 240 GLN 240 240 240 GLN GLN N . n +N 1 241 ASN 241 241 241 ASN ASN N . n +N 1 242 LYS 242 242 242 LYS LYS N . n +N 1 243 ALA 243 243 243 ALA ALA N . n +N 1 244 GLU 244 244 244 GLU GLU N . n +N 1 245 ARG 245 245 245 ARG ARG N . n +N 1 246 GLN 246 246 246 GLN GLN N . n +N 1 247 ASN 247 247 247 ASN ASN N . n +N 1 248 ASP 248 248 248 ASP ASP N . n +N 1 249 ILE 249 249 249 ILE ILE N . n +N 1 250 LEU 250 250 250 LEU LEU N . n +N 1 251 VAL 251 251 251 VAL VAL N . n +N 1 252 LYS 252 252 252 LYS LYS N . n +N 1 253 TYR 253 253 253 TYR TYR N . n +N 1 254 ARG 254 254 254 ARG ARG N . n +N 1 255 HIS 255 255 255 HIS HIS N . n +N 1 256 MET 256 256 256 MET MET N . n +N 1 257 SER 257 257 257 SER SER N . n +N 1 258 VAL 258 258 ? ? ? N . n +N 1 259 PRO 259 259 ? ? ? N . n +N 1 260 PRO 260 260 ? ? ? N . n +N 1 261 GLU 261 261 ? ? ? N . n +N 1 262 SER 262 262 ? ? ? N . n +O 1 1 CYS 1 1 ? ? ? O . n +O 1 2 LEU 2 2 2 LEU LEU O . n +O 1 3 THR 3 3 3 THR THR O . n +O 1 4 ALA 4 4 4 ALA ALA O . n +O 1 5 PRO 5 5 5 PRO PRO O . n +O 1 6 PRO 6 6 6 PRO PRO O . n +O 1 7 LYS 7 7 7 LYS LYS O . n +O 1 8 GLU 8 8 8 GLU GLU O . n +O 1 9 ALA 9 9 9 ALA ALA O . n +O 1 10 ALA 10 10 10 ALA ALA O . n +O 1 11 ARG 11 11 11 ARG ARG O . n +O 1 12 PRO 12 12 12 PRO PRO O . n +O 1 13 THR 13 13 13 THR THR O . n +O 1 14 LEU 14 14 14 LEU LEU O . n +O 1 15 MET 15 15 15 MET MET O . n +O 1 16 PRO 16 16 16 PRO PRO O . n +O 1 17 ARG 17 17 17 ARG ARG O . n +O 1 18 ALA 18 18 18 ALA ALA O . n +O 1 19 GLN 19 19 19 GLN GLN O . n +O 1 20 SER 20 20 20 SER SER O . n +O 1 21 TYR 21 21 21 TYR TYR O . n +O 1 22 LYS 22 22 22 LYS LYS O . n +O 1 23 ASP 23 23 23 ASP ASP O . n +O 1 24 LEU 24 24 24 LEU LEU O . n +O 1 25 THR 25 25 25 THR THR O . n +O 1 26 HIS 26 26 26 HIS HIS O . n +O 1 27 LEU 27 27 27 LEU LEU O . n +O 1 28 PRO 28 28 28 PRO PRO O . n +O 1 29 ALA 29 29 29 ALA ALA O . n +O 1 30 PRO 30 30 30 PRO PRO O . n +O 1 31 THR 31 31 31 THR THR O . n +O 1 32 GLY 32 32 32 GLY GLY O . n +O 1 33 LYS 33 33 33 LYS LYS O . n +O 1 34 ILE 34 34 34 ILE ILE O . n +O 1 35 PHE 35 35 35 PHE PHE O . n +O 1 36 VAL 36 36 36 VAL VAL O . n +O 1 37 SER 37 37 37 SER SER O . n +O 1 38 VAL 38 38 38 VAL VAL O . n +O 1 39 TYR 39 39 39 TYR TYR O . n +O 1 40 ASN 40 40 40 ASN ASN O . n +O 1 41 ILE 41 41 41 ILE ILE O . n +O 1 42 GLN 42 42 42 GLN GLN O . n +O 1 43 ASP 43 43 43 ASP ASP O . n +O 1 44 GLU 44 44 44 GLU GLU O . n +O 1 45 THR 45 45 45 THR THR O . n +O 1 46 GLY 46 46 46 GLY GLY O . n +O 1 47 GLN 47 47 47 GLN GLN O . n +O 1 48 PHE 48 48 48 PHE PHE O . n +O 1 49 LYS 49 49 49 LYS LYS O . n +O 1 50 PRO 50 50 50 PRO PRO O . n +O 1 51 TYR 51 51 51 TYR TYR O . n +O 1 52 PRO 52 52 52 PRO PRO O . n +O 1 53 ALA 53 53 53 ALA ALA O . n +O 1 54 SER 54 54 54 SER SER O . n +O 1 55 ASN 55 55 55 ASN ASN O . n +O 1 56 PHE 56 56 56 PHE PHE O . n +O 1 57 SER 57 57 57 SER SER O . n +O 1 58 THR 58 58 58 THR THR O . n +O 1 59 ALA 59 59 59 ALA ALA O . n +O 1 60 VAL 60 60 60 VAL VAL O . n +O 1 61 PRO 61 61 61 PRO PRO O . n +O 1 62 GLN 62 62 62 GLN GLN O . n +O 1 63 SER 63 63 63 SER SER O . n +O 1 64 ALA 64 64 64 ALA ALA O . n +O 1 65 THR 65 65 65 THR THR O . n +O 1 66 ALA 66 66 66 ALA ALA O . n +O 1 67 MET 67 67 67 MET MET O . n +O 1 68 LEU 68 68 68 LEU LEU O . n +O 1 69 VAL 69 69 69 VAL VAL O . n +O 1 70 THR 70 70 70 THR THR O . n +O 1 71 ALA 71 71 71 ALA ALA O . n +O 1 72 LEU 72 72 72 LEU LEU O . n +O 1 73 LYS 73 73 73 LYS LYS O . n +O 1 74 ASP 74 74 74 ASP ASP O . n +O 1 75 SER 75 75 75 SER SER O . n +O 1 76 ARG 76 76 76 ARG ARG O . n +O 1 77 TRP 77 77 77 TRP TRP O . n +O 1 78 PHE 78 78 78 PHE PHE O . n +O 1 79 ILE 79 79 79 ILE ILE O . n +O 1 80 PRO 80 80 80 PRO PRO O . n +O 1 81 LEU 81 81 81 LEU LEU O . n +O 1 82 GLU 82 82 82 GLU GLU O . n +O 1 83 ARG 83 83 83 ARG ARG O . n +O 1 84 GLN 84 84 84 GLN GLN O . n +O 1 85 GLY 85 85 85 GLY GLY O . n +O 1 86 LEU 86 86 86 LEU LEU O . n +O 1 87 GLN 87 87 87 GLN GLN O . n +O 1 88 ASN 88 88 88 ASN ASN O . n +O 1 89 LEU 89 89 89 LEU LEU O . n +O 1 90 LEU 90 90 90 LEU LEU O . n +O 1 91 ASN 91 91 91 ASN ASN O . n +O 1 92 GLU 92 92 92 GLU GLU O . n +O 1 93 ARG 93 93 93 ARG ARG O . n +O 1 94 LYS 94 94 94 LYS LYS O . n +O 1 95 ILE 95 95 95 ILE ILE O . n +O 1 96 ILE 96 96 96 ILE ILE O . n +O 1 97 ARG 97 97 97 ARG ARG O . n +O 1 98 ALA 98 98 98 ALA ALA O . n +O 1 99 ALA 99 99 99 ALA ALA O . n +O 1 100 GLN 100 100 100 GLN GLN O . n +O 1 101 GLU 101 101 101 GLU GLU O . n +O 1 102 ASN 102 102 102 ASN ASN O . n +O 1 103 GLY 103 103 103 GLY GLY O . n +O 1 104 THR 104 104 104 THR THR O . n +O 1 105 VAL 105 105 105 VAL VAL O . n +O 1 106 ALA 106 106 106 ALA ALA O . n +O 1 107 ILE 107 107 107 ILE ILE O . n +O 1 108 ASN 108 108 108 ASN ASN O . n +O 1 109 ASN 109 109 109 ASN ASN O . n +O 1 110 ARG 110 110 110 ARG ARG O . n +O 1 111 ILE 111 111 111 ILE ILE O . n +O 1 112 PRO 112 112 112 PRO PRO O . n +O 1 113 LEU 113 113 113 LEU LEU O . n +O 1 114 GLN 114 114 114 GLN GLN O . n +O 1 115 SER 115 115 115 SER SER O . n +O 1 116 LEU 116 116 116 LEU LEU O . n +O 1 117 THR 117 117 117 THR THR O . n +O 1 118 ALA 118 118 118 ALA ALA O . n +O 1 119 ALA 119 119 119 ALA ALA O . n +O 1 120 ASN 120 120 120 ASN ASN O . n +O 1 121 ILE 121 121 121 ILE ILE O . n +O 1 122 MET 122 122 122 MET MET O . n +O 1 123 VAL 123 123 123 VAL VAL O . n +O 1 124 GLU 124 124 124 GLU GLU O . n +O 1 125 GLY 125 125 125 GLY GLY O . n +O 1 126 SER 126 126 126 SER SER O . n +O 1 127 ILE 127 127 127 ILE ILE O . n +O 1 128 ILE 128 128 128 ILE ILE O . n +O 1 129 GLY 129 129 129 GLY GLY O . n +O 1 130 TYR 130 130 130 TYR TYR O . n +O 1 131 GLU 131 131 131 GLU GLU O . n +O 1 132 SER 132 132 132 SER SER O . n +O 1 133 ASN 133 133 133 ASN ASN O . n +O 1 134 VAL 134 134 134 VAL VAL O . n +O 1 135 LYS 135 135 135 LYS LYS O . n +O 1 136 SER 136 136 136 SER SER O . n +O 1 137 GLY 137 137 137 GLY GLY O . n +O 1 138 GLY 138 138 138 GLY GLY O . n +O 1 139 VAL 139 139 139 VAL VAL O . n +O 1 140 GLY 140 140 140 GLY GLY O . n +O 1 141 ALA 141 141 141 ALA ALA O . n +O 1 142 ARG 142 142 142 ARG ARG O . n +O 1 143 TYR 143 143 143 TYR TYR O . n +O 1 144 PHE 144 144 ? ? ? O . n +O 1 145 GLY 145 145 145 GLY GLY O . n +O 1 146 ILE 146 146 146 ILE ILE O . n +O 1 147 GLY 147 147 147 GLY GLY O . n +O 1 148 ALA 148 148 148 ALA ALA O . n +O 1 149 ASP 149 149 149 ASP ASP O . n +O 1 150 THR 150 150 150 THR THR O . n +O 1 151 GLN 151 151 151 GLN GLN O . n +O 1 152 TYR 152 152 152 TYR TYR O . n +O 1 153 GLN 153 153 153 GLN GLN O . n +O 1 154 LEU 154 154 154 LEU LEU O . n +O 1 155 ASP 155 155 155 ASP ASP O . n +O 1 156 GLN 156 156 156 GLN GLN O . n +O 1 157 ILE 157 157 157 ILE ILE O . n +O 1 158 ALA 158 158 158 ALA ALA O . n +O 1 159 VAL 159 159 159 VAL VAL O . n +O 1 160 ASN 160 160 160 ASN ASN O . n +O 1 161 LEU 161 161 161 LEU LEU O . n +O 1 162 ARG 162 162 162 ARG ARG O . n +O 1 163 VAL 163 163 163 VAL VAL O . n +O 1 164 VAL 164 164 164 VAL VAL O . n +O 1 165 ASN 165 165 165 ASN ASN O . n +O 1 166 VAL 166 166 166 VAL VAL O . n +O 1 167 SER 167 167 167 SER SER O . n +O 1 168 THR 168 168 168 THR THR O . n +O 1 169 GLY 169 169 169 GLY GLY O . n +O 1 170 GLU 170 170 170 GLU GLU O . n +O 1 171 ILE 171 171 171 ILE ILE O . n +O 1 172 LEU 172 172 172 LEU LEU O . n +O 1 173 SER 173 173 173 SER SER O . n +O 1 174 SER 174 174 174 SER SER O . n +O 1 175 VAL 175 175 175 VAL VAL O . n +O 1 176 ASN 176 176 176 ASN ASN O . n +O 1 177 THR 177 177 177 THR THR O . n +O 1 178 SER 178 178 178 SER SER O . n +O 1 179 LYS 179 179 179 LYS LYS O . n +O 1 180 THR 180 180 180 THR THR O . n +O 1 181 ILE 181 181 181 ILE ILE O . n +O 1 182 LEU 182 182 182 LEU LEU O . n +O 1 183 SER 183 183 183 SER SER O . n +O 1 184 TYR 184 184 184 TYR TYR O . n +O 1 185 GLU 185 185 185 GLU GLU O . n +O 1 186 VAL 186 186 186 VAL VAL O . n +O 1 187 GLN 187 187 187 GLN GLN O . n +O 1 188 ALA 188 188 188 ALA ALA O . n +O 1 189 GLY 189 189 189 GLY GLY O . n +O 1 190 VAL 190 190 190 VAL VAL O . n +O 1 191 PHE 191 191 191 PHE PHE O . n +O 1 192 ARG 192 192 ? ? ? O . n +O 1 193 PHE 193 193 ? ? ? O . n +O 1 194 ILE 194 194 ? ? ? O . n +O 1 195 ASP 195 195 ? ? ? O . n +O 1 196 TYR 196 196 ? ? ? O . n +O 1 197 GLN 197 197 ? ? ? O . n +O 1 198 ARG 198 198 ? ? ? O . n +O 1 199 LEU 199 199 ? ? ? O . n +O 1 200 LEU 200 200 200 LEU LEU O . n +O 1 201 GLU 201 201 201 GLU GLU O . n +O 1 202 GLY 202 202 202 GLY GLY O . n +O 1 203 GLU 203 203 203 GLU GLU O . n +O 1 204 VAL 204 204 204 VAL VAL O . n +O 1 205 GLY 205 205 205 GLY GLY O . n +O 1 206 TYR 206 206 206 TYR TYR O . n +O 1 207 THR 207 207 207 THR THR O . n +O 1 208 SER 208 208 208 SER SER O . n +O 1 209 ASN 209 209 209 ASN ASN O . n +O 1 210 GLU 210 210 210 GLU GLU O . n +O 1 211 PRO 211 211 211 PRO PRO O . n +O 1 212 VAL 212 212 212 VAL VAL O . n +O 1 213 MET 213 213 213 MET MET O . n +O 1 214 LEU 214 214 214 LEU LEU O . n +O 1 215 CYS 215 215 215 CYS CYS O . n +O 1 216 LEU 216 216 216 LEU LEU O . n +O 1 217 MET 217 217 217 MET MET O . n +O 1 218 SER 218 218 218 SER SER O . n +O 1 219 ALA 219 219 219 ALA ALA O . n +O 1 220 ILE 220 220 220 ILE ILE O . n +O 1 221 GLU 221 221 221 GLU GLU O . n +O 1 222 THR 222 222 222 THR THR O . n +O 1 223 GLY 223 223 223 GLY GLY O . n +O 1 224 VAL 224 224 224 VAL VAL O . n +O 1 225 ILE 225 225 225 ILE ILE O . n +O 1 226 PHE 226 226 226 PHE PHE O . n +O 1 227 LEU 227 227 227 LEU LEU O . n +O 1 228 ILE 228 228 228 ILE ILE O . n +O 1 229 ASN 229 229 229 ASN ASN O . n +O 1 230 ASP 230 230 230 ASP ASP O . n +O 1 231 GLY 231 231 231 GLY GLY O . n +O 1 232 ILE 232 232 232 ILE ILE O . n +O 1 233 ASP 233 233 233 ASP ASP O . n +O 1 234 ARG 234 234 234 ARG ARG O . n +O 1 235 GLY 235 235 235 GLY GLY O . n +O 1 236 LEU 236 236 236 LEU LEU O . n +O 1 237 TRP 237 237 237 TRP TRP O . n +O 1 238 ASP 238 238 238 ASP ASP O . n +O 1 239 LEU 239 239 239 LEU LEU O . n +O 1 240 GLN 240 240 240 GLN GLN O . n +O 1 241 ASN 241 241 241 ASN ASN O . n +O 1 242 LYS 242 242 242 LYS LYS O . n +O 1 243 ALA 243 243 243 ALA ALA O . n +O 1 244 GLU 244 244 244 GLU GLU O . n +O 1 245 ARG 245 245 245 ARG ARG O . n +O 1 246 GLN 246 246 246 GLN GLN O . n +O 1 247 ASN 247 247 247 ASN ASN O . n +O 1 248 ASP 248 248 248 ASP ASP O . n +O 1 249 ILE 249 249 249 ILE ILE O . n +O 1 250 LEU 250 250 250 LEU LEU O . n +O 1 251 VAL 251 251 251 VAL VAL O . n +O 1 252 LYS 252 252 252 LYS LYS O . n +O 1 253 TYR 253 253 253 TYR TYR O . n +O 1 254 ARG 254 254 254 ARG ARG O . n +O 1 255 HIS 255 255 255 HIS HIS O . n +O 1 256 MET 256 256 256 MET MET O . n +O 1 257 SER 257 257 257 SER SER O . n +O 1 258 VAL 258 258 ? ? ? O . n +O 1 259 PRO 259 259 ? ? ? O . n +O 1 260 PRO 260 260 ? ? ? O . n +O 1 261 GLU 261 261 ? ? ? O . n +O 1 262 SER 262 262 ? ? ? O . n +P 1 1 CYS 1 1 ? ? ? P . n +P 1 2 LEU 2 2 2 LEU LEU P . n +P 1 3 THR 3 3 3 THR THR P . n +P 1 4 ALA 4 4 4 ALA ALA P . n +P 1 5 PRO 5 5 5 PRO PRO P . n +P 1 6 PRO 6 6 6 PRO PRO P . n +P 1 7 LYS 7 7 7 LYS LYS P . n +P 1 8 GLU 8 8 8 GLU GLU P . n +P 1 9 ALA 9 9 9 ALA ALA P . n +P 1 10 ALA 10 10 10 ALA ALA P . n +P 1 11 ARG 11 11 11 ARG ARG P . n +P 1 12 PRO 12 12 12 PRO PRO P . n +P 1 13 THR 13 13 13 THR THR P . n +P 1 14 LEU 14 14 14 LEU LEU P . n +P 1 15 MET 15 15 15 MET MET P . n +P 1 16 PRO 16 16 16 PRO PRO P . n +P 1 17 ARG 17 17 17 ARG ARG P . n +P 1 18 ALA 18 18 18 ALA ALA P . n +P 1 19 GLN 19 19 19 GLN GLN P . n +P 1 20 SER 20 20 20 SER SER P . n +P 1 21 TYR 21 21 21 TYR TYR P . n +P 1 22 LYS 22 22 22 LYS LYS P . n +P 1 23 ASP 23 23 23 ASP ASP P . n +P 1 24 LEU 24 24 24 LEU LEU P . n +P 1 25 THR 25 25 25 THR THR P . n +P 1 26 HIS 26 26 26 HIS HIS P . n +P 1 27 LEU 27 27 27 LEU LEU P . n +P 1 28 PRO 28 28 28 PRO PRO P . n +P 1 29 ALA 29 29 29 ALA ALA P . n +P 1 30 PRO 30 30 30 PRO PRO P . n +P 1 31 THR 31 31 31 THR THR P . n +P 1 32 GLY 32 32 32 GLY GLY P . n +P 1 33 LYS 33 33 33 LYS LYS P . n +P 1 34 ILE 34 34 34 ILE ILE P . n +P 1 35 PHE 35 35 35 PHE PHE P . n +P 1 36 VAL 36 36 36 VAL VAL P . n +P 1 37 SER 37 37 37 SER SER P . n +P 1 38 VAL 38 38 38 VAL VAL P . n +P 1 39 TYR 39 39 39 TYR TYR P . n +P 1 40 ASN 40 40 40 ASN ASN P . n +P 1 41 ILE 41 41 41 ILE ILE P . n +P 1 42 GLN 42 42 42 GLN GLN P . n +P 1 43 ASP 43 43 43 ASP ASP P . n +P 1 44 GLU 44 44 44 GLU GLU P . n +P 1 45 THR 45 45 45 THR THR P . n +P 1 46 GLY 46 46 46 GLY GLY P . n +P 1 47 GLN 47 47 47 GLN GLN P . n +P 1 48 PHE 48 48 48 PHE PHE P . n +P 1 49 LYS 49 49 49 LYS LYS P . n +P 1 50 PRO 50 50 50 PRO PRO P . n +P 1 51 TYR 51 51 51 TYR TYR P . n +P 1 52 PRO 52 52 52 PRO PRO P . n +P 1 53 ALA 53 53 53 ALA ALA P . n +P 1 54 SER 54 54 54 SER SER P . n +P 1 55 ASN 55 55 55 ASN ASN P . n +P 1 56 PHE 56 56 56 PHE PHE P . n +P 1 57 SER 57 57 57 SER SER P . n +P 1 58 THR 58 58 58 THR THR P . n +P 1 59 ALA 59 59 59 ALA ALA P . n +P 1 60 VAL 60 60 60 VAL VAL P . n +P 1 61 PRO 61 61 61 PRO PRO P . n +P 1 62 GLN 62 62 62 GLN GLN P . n +P 1 63 SER 63 63 63 SER SER P . n +P 1 64 ALA 64 64 64 ALA ALA P . n +P 1 65 THR 65 65 65 THR THR P . n +P 1 66 ALA 66 66 66 ALA ALA P . n +P 1 67 MET 67 67 67 MET MET P . n +P 1 68 LEU 68 68 68 LEU LEU P . n +P 1 69 VAL 69 69 69 VAL VAL P . n +P 1 70 THR 70 70 70 THR THR P . n +P 1 71 ALA 71 71 71 ALA ALA P . n +P 1 72 LEU 72 72 72 LEU LEU P . n +P 1 73 LYS 73 73 73 LYS LYS P . n +P 1 74 ASP 74 74 74 ASP ASP P . n +P 1 75 SER 75 75 75 SER SER P . n +P 1 76 ARG 76 76 76 ARG ARG P . n +P 1 77 TRP 77 77 77 TRP TRP P . n +P 1 78 PHE 78 78 78 PHE PHE P . n +P 1 79 ILE 79 79 79 ILE ILE P . n +P 1 80 PRO 80 80 80 PRO PRO P . n +P 1 81 LEU 81 81 81 LEU LEU P . n +P 1 82 GLU 82 82 82 GLU GLU P . n +P 1 83 ARG 83 83 83 ARG ARG P . n +P 1 84 GLN 84 84 84 GLN GLN P . n +P 1 85 GLY 85 85 85 GLY GLY P . n +P 1 86 LEU 86 86 86 LEU LEU P . n +P 1 87 GLN 87 87 87 GLN GLN P . n +P 1 88 ASN 88 88 88 ASN ASN P . n +P 1 89 LEU 89 89 89 LEU LEU P . n +P 1 90 LEU 90 90 90 LEU LEU P . n +P 1 91 ASN 91 91 91 ASN ASN P . n +P 1 92 GLU 92 92 92 GLU GLU P . n +P 1 93 ARG 93 93 93 ARG ARG P . n +P 1 94 LYS 94 94 94 LYS LYS P . n +P 1 95 ILE 95 95 95 ILE ILE P . n +P 1 96 ILE 96 96 96 ILE ILE P . n +P 1 97 ARG 97 97 97 ARG ARG P . n +P 1 98 ALA 98 98 98 ALA ALA P . n +P 1 99 ALA 99 99 99 ALA ALA P . n +P 1 100 GLN 100 100 100 GLN GLN P . n +P 1 101 GLU 101 101 101 GLU GLU P . n +P 1 102 ASN 102 102 102 ASN ASN P . n +P 1 103 GLY 103 103 103 GLY GLY P . n +P 1 104 THR 104 104 104 THR THR P . n +P 1 105 VAL 105 105 105 VAL VAL P . n +P 1 106 ALA 106 106 106 ALA ALA P . n +P 1 107 ILE 107 107 107 ILE ILE P . n +P 1 108 ASN 108 108 108 ASN ASN P . n +P 1 109 ASN 109 109 109 ASN ASN P . n +P 1 110 ARG 110 110 110 ARG ARG P . n +P 1 111 ILE 111 111 111 ILE ILE P . n +P 1 112 PRO 112 112 112 PRO PRO P . n +P 1 113 LEU 113 113 113 LEU LEU P . n +P 1 114 GLN 114 114 114 GLN GLN P . n +P 1 115 SER 115 115 115 SER SER P . n +P 1 116 LEU 116 116 116 LEU LEU P . n +P 1 117 THR 117 117 117 THR THR P . n +P 1 118 ALA 118 118 118 ALA ALA P . n +P 1 119 ALA 119 119 119 ALA ALA P . n +P 1 120 ASN 120 120 120 ASN ASN P . n +P 1 121 ILE 121 121 121 ILE ILE P . n +P 1 122 MET 122 122 122 MET MET P . n +P 1 123 VAL 123 123 123 VAL VAL P . n +P 1 124 GLU 124 124 124 GLU GLU P . n +P 1 125 GLY 125 125 125 GLY GLY P . n +P 1 126 SER 126 126 126 SER SER P . n +P 1 127 ILE 127 127 127 ILE ILE P . n +P 1 128 ILE 128 128 128 ILE ILE P . n +P 1 129 GLY 129 129 129 GLY GLY P . n +P 1 130 TYR 130 130 130 TYR TYR P . n +P 1 131 GLU 131 131 131 GLU GLU P . n +P 1 132 SER 132 132 132 SER SER P . n +P 1 133 ASN 133 133 133 ASN ASN P . n +P 1 134 VAL 134 134 134 VAL VAL P . n +P 1 135 LYS 135 135 135 LYS LYS P . n +P 1 136 SER 136 136 136 SER SER P . n +P 1 137 GLY 137 137 137 GLY GLY P . n +P 1 138 GLY 138 138 138 GLY GLY P . n +P 1 139 VAL 139 139 139 VAL VAL P . n +P 1 140 GLY 140 140 140 GLY GLY P . n +P 1 141 ALA 141 141 141 ALA ALA P . n +P 1 142 ARG 142 142 142 ARG ARG P . n +P 1 143 TYR 143 143 143 TYR TYR P . n +P 1 144 PHE 144 144 ? ? ? P . n +P 1 145 GLY 145 145 145 GLY GLY P . n +P 1 146 ILE 146 146 146 ILE ILE P . n +P 1 147 GLY 147 147 147 GLY GLY P . n +P 1 148 ALA 148 148 148 ALA ALA P . n +P 1 149 ASP 149 149 149 ASP ASP P . n +P 1 150 THR 150 150 150 THR THR P . n +P 1 151 GLN 151 151 151 GLN GLN P . n +P 1 152 TYR 152 152 152 TYR TYR P . n +P 1 153 GLN 153 153 153 GLN GLN P . n +P 1 154 LEU 154 154 154 LEU LEU P . n +P 1 155 ASP 155 155 155 ASP ASP P . n +P 1 156 GLN 156 156 156 GLN GLN P . n +P 1 157 ILE 157 157 157 ILE ILE P . n +P 1 158 ALA 158 158 158 ALA ALA P . n +P 1 159 VAL 159 159 159 VAL VAL P . n +P 1 160 ASN 160 160 160 ASN ASN P . n +P 1 161 LEU 161 161 161 LEU LEU P . n +P 1 162 ARG 162 162 162 ARG ARG P . n +P 1 163 VAL 163 163 163 VAL VAL P . n +P 1 164 VAL 164 164 164 VAL VAL P . n +P 1 165 ASN 165 165 165 ASN ASN P . n +P 1 166 VAL 166 166 166 VAL VAL P . n +P 1 167 SER 167 167 167 SER SER P . n +P 1 168 THR 168 168 168 THR THR P . n +P 1 169 GLY 169 169 169 GLY GLY P . n +P 1 170 GLU 170 170 170 GLU GLU P . n +P 1 171 ILE 171 171 171 ILE ILE P . n +P 1 172 LEU 172 172 172 LEU LEU P . n +P 1 173 SER 173 173 173 SER SER P . n +P 1 174 SER 174 174 174 SER SER P . n +P 1 175 VAL 175 175 175 VAL VAL P . n +P 1 176 ASN 176 176 176 ASN ASN P . n +P 1 177 THR 177 177 177 THR THR P . n +P 1 178 SER 178 178 178 SER SER P . n +P 1 179 LYS 179 179 179 LYS LYS P . n +P 1 180 THR 180 180 180 THR THR P . n +P 1 181 ILE 181 181 181 ILE ILE P . n +P 1 182 LEU 182 182 182 LEU LEU P . n +P 1 183 SER 183 183 183 SER SER P . n +P 1 184 TYR 184 184 184 TYR TYR P . n +P 1 185 GLU 185 185 185 GLU GLU P . n +P 1 186 VAL 186 186 186 VAL VAL P . n +P 1 187 GLN 187 187 187 GLN GLN P . n +P 1 188 ALA 188 188 188 ALA ALA P . n +P 1 189 GLY 189 189 189 GLY GLY P . n +P 1 190 VAL 190 190 190 VAL VAL P . n +P 1 191 PHE 191 191 191 PHE PHE P . n +P 1 192 ARG 192 192 ? ? ? P . n +P 1 193 PHE 193 193 ? ? ? P . n +P 1 194 ILE 194 194 ? ? ? P . n +P 1 195 ASP 195 195 ? ? ? P . n +P 1 196 TYR 196 196 ? ? ? P . n +P 1 197 GLN 197 197 ? ? ? P . n +P 1 198 ARG 198 198 ? ? ? P . n +P 1 199 LEU 199 199 ? ? ? P . n +P 1 200 LEU 200 200 200 LEU LEU P . n +P 1 201 GLU 201 201 201 GLU GLU P . n +P 1 202 GLY 202 202 202 GLY GLY P . n +P 1 203 GLU 203 203 203 GLU GLU P . n +P 1 204 VAL 204 204 204 VAL VAL P . n +P 1 205 GLY 205 205 205 GLY GLY P . n +P 1 206 TYR 206 206 206 TYR TYR P . n +P 1 207 THR 207 207 207 THR THR P . n +P 1 208 SER 208 208 208 SER SER P . n +P 1 209 ASN 209 209 209 ASN ASN P . n +P 1 210 GLU 210 210 210 GLU GLU P . n +P 1 211 PRO 211 211 211 PRO PRO P . n +P 1 212 VAL 212 212 212 VAL VAL P . n +P 1 213 MET 213 213 213 MET MET P . n +P 1 214 LEU 214 214 214 LEU LEU P . n +P 1 215 CYS 215 215 215 CYS CYS P . n +P 1 216 LEU 216 216 216 LEU LEU P . n +P 1 217 MET 217 217 217 MET MET P . n +P 1 218 SER 218 218 218 SER SER P . n +P 1 219 ALA 219 219 219 ALA ALA P . n +P 1 220 ILE 220 220 220 ILE ILE P . n +P 1 221 GLU 221 221 221 GLU GLU P . n +P 1 222 THR 222 222 222 THR THR P . n +P 1 223 GLY 223 223 223 GLY GLY P . n +P 1 224 VAL 224 224 224 VAL VAL P . n +P 1 225 ILE 225 225 225 ILE ILE P . n +P 1 226 PHE 226 226 226 PHE PHE P . n +P 1 227 LEU 227 227 227 LEU LEU P . n +P 1 228 ILE 228 228 228 ILE ILE P . n +P 1 229 ASN 229 229 229 ASN ASN P . n +P 1 230 ASP 230 230 230 ASP ASP P . n +P 1 231 GLY 231 231 231 GLY GLY P . n +P 1 232 ILE 232 232 232 ILE ILE P . n +P 1 233 ASP 233 233 233 ASP ASP P . n +P 1 234 ARG 234 234 234 ARG ARG P . n +P 1 235 GLY 235 235 235 GLY GLY P . n +P 1 236 LEU 236 236 236 LEU LEU P . n +P 1 237 TRP 237 237 237 TRP TRP P . n +P 1 238 ASP 238 238 238 ASP ASP P . n +P 1 239 LEU 239 239 239 LEU LEU P . n +P 1 240 GLN 240 240 240 GLN GLN P . n +P 1 241 ASN 241 241 241 ASN ASN P . n +P 1 242 LYS 242 242 242 LYS LYS P . n +P 1 243 ALA 243 243 243 ALA ALA P . n +P 1 244 GLU 244 244 244 GLU GLU P . n +P 1 245 ARG 245 245 245 ARG ARG P . n +P 1 246 GLN 246 246 246 GLN GLN P . n +P 1 247 ASN 247 247 247 ASN ASN P . n +P 1 248 ASP 248 248 248 ASP ASP P . n +P 1 249 ILE 249 249 249 ILE ILE P . n +P 1 250 LEU 250 250 250 LEU LEU P . n +P 1 251 VAL 251 251 251 VAL VAL P . n +P 1 252 LYS 252 252 252 LYS LYS P . n +P 1 253 TYR 253 253 253 TYR TYR P . n +P 1 254 ARG 254 254 254 ARG ARG P . n +P 1 255 HIS 255 255 255 HIS HIS P . n +P 1 256 MET 256 256 256 MET MET P . n +P 1 257 SER 257 257 257 SER SER P . n +P 1 258 VAL 258 258 ? ? ? P . n +P 1 259 PRO 259 259 ? ? ? P . n +P 1 260 PRO 260 260 ? ? ? P . n +P 1 261 GLU 261 261 ? ? ? P . n +P 1 262 SER 262 262 ? ? ? P . n +Q 1 1 CYS 1 1 ? ? ? Q . n +Q 1 2 LEU 2 2 2 LEU LEU Q . n +Q 1 3 THR 3 3 3 THR THR Q . n +Q 1 4 ALA 4 4 4 ALA ALA Q . n +Q 1 5 PRO 5 5 5 PRO PRO Q . n +Q 1 6 PRO 6 6 6 PRO PRO Q . n +Q 1 7 LYS 7 7 7 LYS LYS Q . n +Q 1 8 GLU 8 8 8 GLU GLU Q . n +Q 1 9 ALA 9 9 9 ALA ALA Q . n +Q 1 10 ALA 10 10 10 ALA ALA Q . n +Q 1 11 ARG 11 11 11 ARG ARG Q . n +Q 1 12 PRO 12 12 12 PRO PRO Q . n +Q 1 13 THR 13 13 13 THR THR Q . n +Q 1 14 LEU 14 14 14 LEU LEU Q . n +Q 1 15 MET 15 15 15 MET MET Q . n +Q 1 16 PRO 16 16 16 PRO PRO Q . n +Q 1 17 ARG 17 17 17 ARG ARG Q . n +Q 1 18 ALA 18 18 18 ALA ALA Q . n +Q 1 19 GLN 19 19 19 GLN GLN Q . n +Q 1 20 SER 20 20 20 SER SER Q . n +Q 1 21 TYR 21 21 21 TYR TYR Q . n +Q 1 22 LYS 22 22 22 LYS LYS Q . n +Q 1 23 ASP 23 23 23 ASP ASP Q . n +Q 1 24 LEU 24 24 24 LEU LEU Q . n +Q 1 25 THR 25 25 25 THR THR Q . n +Q 1 26 HIS 26 26 26 HIS HIS Q . n +Q 1 27 LEU 27 27 27 LEU LEU Q . n +Q 1 28 PRO 28 28 28 PRO PRO Q . n +Q 1 29 ALA 29 29 29 ALA ALA Q . n +Q 1 30 PRO 30 30 30 PRO PRO Q . n +Q 1 31 THR 31 31 31 THR THR Q . n +Q 1 32 GLY 32 32 32 GLY GLY Q . n +Q 1 33 LYS 33 33 33 LYS LYS Q . n +Q 1 34 ILE 34 34 34 ILE ILE Q . n +Q 1 35 PHE 35 35 35 PHE PHE Q . n +Q 1 36 VAL 36 36 36 VAL VAL Q . n +Q 1 37 SER 37 37 37 SER SER Q . n +Q 1 38 VAL 38 38 38 VAL VAL Q . n +Q 1 39 TYR 39 39 39 TYR TYR Q . n +Q 1 40 ASN 40 40 40 ASN ASN Q . n +Q 1 41 ILE 41 41 41 ILE ILE Q . n +Q 1 42 GLN 42 42 42 GLN GLN Q . n +Q 1 43 ASP 43 43 43 ASP ASP Q . n +Q 1 44 GLU 44 44 44 GLU GLU Q . n +Q 1 45 THR 45 45 45 THR THR Q . n +Q 1 46 GLY 46 46 46 GLY GLY Q . n +Q 1 47 GLN 47 47 47 GLN GLN Q . n +Q 1 48 PHE 48 48 48 PHE PHE Q . n +Q 1 49 LYS 49 49 49 LYS LYS Q . n +Q 1 50 PRO 50 50 50 PRO PRO Q . n +Q 1 51 TYR 51 51 51 TYR TYR Q . n +Q 1 52 PRO 52 52 52 PRO PRO Q . n +Q 1 53 ALA 53 53 53 ALA ALA Q . n +Q 1 54 SER 54 54 54 SER SER Q . n +Q 1 55 ASN 55 55 55 ASN ASN Q . n +Q 1 56 PHE 56 56 56 PHE PHE Q . n +Q 1 57 SER 57 57 57 SER SER Q . n +Q 1 58 THR 58 58 58 THR THR Q . n +Q 1 59 ALA 59 59 59 ALA ALA Q . n +Q 1 60 VAL 60 60 60 VAL VAL Q . n +Q 1 61 PRO 61 61 61 PRO PRO Q . n +Q 1 62 GLN 62 62 62 GLN GLN Q . n +Q 1 63 SER 63 63 63 SER SER Q . n +Q 1 64 ALA 64 64 64 ALA ALA Q . n +Q 1 65 THR 65 65 65 THR THR Q . n +Q 1 66 ALA 66 66 66 ALA ALA Q . n +Q 1 67 MET 67 67 67 MET MET Q . n +Q 1 68 LEU 68 68 68 LEU LEU Q . n +Q 1 69 VAL 69 69 69 VAL VAL Q . n +Q 1 70 THR 70 70 70 THR THR Q . n +Q 1 71 ALA 71 71 71 ALA ALA Q . n +Q 1 72 LEU 72 72 72 LEU LEU Q . n +Q 1 73 LYS 73 73 73 LYS LYS Q . n +Q 1 74 ASP 74 74 74 ASP ASP Q . n +Q 1 75 SER 75 75 75 SER SER Q . n +Q 1 76 ARG 76 76 76 ARG ARG Q . n +Q 1 77 TRP 77 77 77 TRP TRP Q . n +Q 1 78 PHE 78 78 78 PHE PHE Q . n +Q 1 79 ILE 79 79 79 ILE ILE Q . n +Q 1 80 PRO 80 80 80 PRO PRO Q . n +Q 1 81 LEU 81 81 81 LEU LEU Q . n +Q 1 82 GLU 82 82 82 GLU GLU Q . n +Q 1 83 ARG 83 83 83 ARG ARG Q . n +Q 1 84 GLN 84 84 84 GLN GLN Q . n +Q 1 85 GLY 85 85 85 GLY GLY Q . n +Q 1 86 LEU 86 86 86 LEU LEU Q . n +Q 1 87 GLN 87 87 87 GLN GLN Q . n +Q 1 88 ASN 88 88 88 ASN ASN Q . n +Q 1 89 LEU 89 89 89 LEU LEU Q . n +Q 1 90 LEU 90 90 90 LEU LEU Q . n +Q 1 91 ASN 91 91 91 ASN ASN Q . n +Q 1 92 GLU 92 92 92 GLU GLU Q . n +Q 1 93 ARG 93 93 93 ARG ARG Q . n +Q 1 94 LYS 94 94 94 LYS LYS Q . n +Q 1 95 ILE 95 95 95 ILE ILE Q . n +Q 1 96 ILE 96 96 96 ILE ILE Q . n +Q 1 97 ARG 97 97 97 ARG ARG Q . n +Q 1 98 ALA 98 98 98 ALA ALA Q . n +Q 1 99 ALA 99 99 99 ALA ALA Q . n +Q 1 100 GLN 100 100 100 GLN GLN Q . n +Q 1 101 GLU 101 101 101 GLU GLU Q . n +Q 1 102 ASN 102 102 102 ASN ASN Q . n +Q 1 103 GLY 103 103 103 GLY GLY Q . n +Q 1 104 THR 104 104 104 THR THR Q . n +Q 1 105 VAL 105 105 105 VAL VAL Q . n +Q 1 106 ALA 106 106 106 ALA ALA Q . n +Q 1 107 ILE 107 107 107 ILE ILE Q . n +Q 1 108 ASN 108 108 108 ASN ASN Q . n +Q 1 109 ASN 109 109 109 ASN ASN Q . n +Q 1 110 ARG 110 110 110 ARG ARG Q . n +Q 1 111 ILE 111 111 111 ILE ILE Q . n +Q 1 112 PRO 112 112 112 PRO PRO Q . n +Q 1 113 LEU 113 113 113 LEU LEU Q . n +Q 1 114 GLN 114 114 114 GLN GLN Q . n +Q 1 115 SER 115 115 115 SER SER Q . n +Q 1 116 LEU 116 116 116 LEU LEU Q . n +Q 1 117 THR 117 117 117 THR THR Q . n +Q 1 118 ALA 118 118 118 ALA ALA Q . n +Q 1 119 ALA 119 119 119 ALA ALA Q . n +Q 1 120 ASN 120 120 120 ASN ASN Q . n +Q 1 121 ILE 121 121 121 ILE ILE Q . n +Q 1 122 MET 122 122 122 MET MET Q . n +Q 1 123 VAL 123 123 123 VAL VAL Q . n +Q 1 124 GLU 124 124 124 GLU GLU Q . n +Q 1 125 GLY 125 125 125 GLY GLY Q . n +Q 1 126 SER 126 126 126 SER SER Q . n +Q 1 127 ILE 127 127 127 ILE ILE Q . n +Q 1 128 ILE 128 128 128 ILE ILE Q . n +Q 1 129 GLY 129 129 129 GLY GLY Q . n +Q 1 130 TYR 130 130 130 TYR TYR Q . n +Q 1 131 GLU 131 131 131 GLU GLU Q . n +Q 1 132 SER 132 132 132 SER SER Q . n +Q 1 133 ASN 133 133 133 ASN ASN Q . n +Q 1 134 VAL 134 134 134 VAL VAL Q . n +Q 1 135 LYS 135 135 135 LYS LYS Q . n +Q 1 136 SER 136 136 136 SER SER Q . n +Q 1 137 GLY 137 137 137 GLY GLY Q . n +Q 1 138 GLY 138 138 138 GLY GLY Q . n +Q 1 139 VAL 139 139 139 VAL VAL Q . n +Q 1 140 GLY 140 140 140 GLY GLY Q . n +Q 1 141 ALA 141 141 141 ALA ALA Q . n +Q 1 142 ARG 142 142 142 ARG ARG Q . n +Q 1 143 TYR 143 143 143 TYR TYR Q . n +Q 1 144 PHE 144 144 ? ? ? Q . n +Q 1 145 GLY 145 145 145 GLY GLY Q . n +Q 1 146 ILE 146 146 146 ILE ILE Q . n +Q 1 147 GLY 147 147 147 GLY GLY Q . n +Q 1 148 ALA 148 148 148 ALA ALA Q . n +Q 1 149 ASP 149 149 149 ASP ASP Q . n +Q 1 150 THR 150 150 150 THR THR Q . n +Q 1 151 GLN 151 151 151 GLN GLN Q . n +Q 1 152 TYR 152 152 152 TYR TYR Q . n +Q 1 153 GLN 153 153 153 GLN GLN Q . n +Q 1 154 LEU 154 154 154 LEU LEU Q . n +Q 1 155 ASP 155 155 155 ASP ASP Q . n +Q 1 156 GLN 156 156 156 GLN GLN Q . n +Q 1 157 ILE 157 157 157 ILE ILE Q . n +Q 1 158 ALA 158 158 158 ALA ALA Q . n +Q 1 159 VAL 159 159 159 VAL VAL Q . n +Q 1 160 ASN 160 160 160 ASN ASN Q . n +Q 1 161 LEU 161 161 161 LEU LEU Q . n +Q 1 162 ARG 162 162 162 ARG ARG Q . n +Q 1 163 VAL 163 163 163 VAL VAL Q . n +Q 1 164 VAL 164 164 164 VAL VAL Q . n +Q 1 165 ASN 165 165 165 ASN ASN Q . n +Q 1 166 VAL 166 166 166 VAL VAL Q . n +Q 1 167 SER 167 167 167 SER SER Q . n +Q 1 168 THR 168 168 168 THR THR Q . n +Q 1 169 GLY 169 169 169 GLY GLY Q . n +Q 1 170 GLU 170 170 170 GLU GLU Q . n +Q 1 171 ILE 171 171 171 ILE ILE Q . n +Q 1 172 LEU 172 172 172 LEU LEU Q . n +Q 1 173 SER 173 173 173 SER SER Q . n +Q 1 174 SER 174 174 174 SER SER Q . n +Q 1 175 VAL 175 175 175 VAL VAL Q . n +Q 1 176 ASN 176 176 176 ASN ASN Q . n +Q 1 177 THR 177 177 177 THR THR Q . n +Q 1 178 SER 178 178 178 SER SER Q . n +Q 1 179 LYS 179 179 179 LYS LYS Q . n +Q 1 180 THR 180 180 180 THR THR Q . n +Q 1 181 ILE 181 181 181 ILE ILE Q . n +Q 1 182 LEU 182 182 182 LEU LEU Q . n +Q 1 183 SER 183 183 183 SER SER Q . n +Q 1 184 TYR 184 184 184 TYR TYR Q . n +Q 1 185 GLU 185 185 185 GLU GLU Q . n +Q 1 186 VAL 186 186 186 VAL VAL Q . n +Q 1 187 GLN 187 187 187 GLN GLN Q . n +Q 1 188 ALA 188 188 188 ALA ALA Q . n +Q 1 189 GLY 189 189 189 GLY GLY Q . n +Q 1 190 VAL 190 190 190 VAL VAL Q . n +Q 1 191 PHE 191 191 191 PHE PHE Q . n +Q 1 192 ARG 192 192 ? ? ? Q . n +Q 1 193 PHE 193 193 ? ? ? Q . n +Q 1 194 ILE 194 194 ? ? ? Q . n +Q 1 195 ASP 195 195 ? ? ? Q . n +Q 1 196 TYR 196 196 ? ? ? Q . n +Q 1 197 GLN 197 197 ? ? ? Q . n +Q 1 198 ARG 198 198 ? ? ? Q . n +Q 1 199 LEU 199 199 ? ? ? Q . n +Q 1 200 LEU 200 200 200 LEU LEU Q . n +Q 1 201 GLU 201 201 201 GLU GLU Q . n +Q 1 202 GLY 202 202 202 GLY GLY Q . n +Q 1 203 GLU 203 203 203 GLU GLU Q . n +Q 1 204 VAL 204 204 204 VAL VAL Q . n +Q 1 205 GLY 205 205 205 GLY GLY Q . n +Q 1 206 TYR 206 206 206 TYR TYR Q . n +Q 1 207 THR 207 207 207 THR THR Q . n +Q 1 208 SER 208 208 208 SER SER Q . n +Q 1 209 ASN 209 209 209 ASN ASN Q . n +Q 1 210 GLU 210 210 210 GLU GLU Q . n +Q 1 211 PRO 211 211 211 PRO PRO Q . n +Q 1 212 VAL 212 212 212 VAL VAL Q . n +Q 1 213 MET 213 213 213 MET MET Q . n +Q 1 214 LEU 214 214 214 LEU LEU Q . n +Q 1 215 CYS 215 215 215 CYS CYS Q . n +Q 1 216 LEU 216 216 216 LEU LEU Q . n +Q 1 217 MET 217 217 217 MET MET Q . n +Q 1 218 SER 218 218 218 SER SER Q . n +Q 1 219 ALA 219 219 219 ALA ALA Q . n +Q 1 220 ILE 220 220 220 ILE ILE Q . n +Q 1 221 GLU 221 221 221 GLU GLU Q . n +Q 1 222 THR 222 222 222 THR THR Q . n +Q 1 223 GLY 223 223 223 GLY GLY Q . n +Q 1 224 VAL 224 224 224 VAL VAL Q . n +Q 1 225 ILE 225 225 225 ILE ILE Q . n +Q 1 226 PHE 226 226 226 PHE PHE Q . n +Q 1 227 LEU 227 227 227 LEU LEU Q . n +Q 1 228 ILE 228 228 228 ILE ILE Q . n +Q 1 229 ASN 229 229 229 ASN ASN Q . n +Q 1 230 ASP 230 230 230 ASP ASP Q . n +Q 1 231 GLY 231 231 231 GLY GLY Q . n +Q 1 232 ILE 232 232 232 ILE ILE Q . n +Q 1 233 ASP 233 233 233 ASP ASP Q . n +Q 1 234 ARG 234 234 234 ARG ARG Q . n +Q 1 235 GLY 235 235 235 GLY GLY Q . n +Q 1 236 LEU 236 236 236 LEU LEU Q . n +Q 1 237 TRP 237 237 237 TRP TRP Q . n +Q 1 238 ASP 238 238 238 ASP ASP Q . n +Q 1 239 LEU 239 239 239 LEU LEU Q . n +Q 1 240 GLN 240 240 240 GLN GLN Q . n +Q 1 241 ASN 241 241 241 ASN ASN Q . n +Q 1 242 LYS 242 242 242 LYS LYS Q . n +Q 1 243 ALA 243 243 243 ALA ALA Q . n +Q 1 244 GLU 244 244 244 GLU GLU Q . n +Q 1 245 ARG 245 245 245 ARG ARG Q . n +Q 1 246 GLN 246 246 246 GLN GLN Q . n +Q 1 247 ASN 247 247 247 ASN ASN Q . n +Q 1 248 ASP 248 248 248 ASP ASP Q . n +Q 1 249 ILE 249 249 249 ILE ILE Q . n +Q 1 250 LEU 250 250 250 LEU LEU Q . n +Q 1 251 VAL 251 251 251 VAL VAL Q . n +Q 1 252 LYS 252 252 252 LYS LYS Q . n +Q 1 253 TYR 253 253 253 TYR TYR Q . n +Q 1 254 ARG 254 254 254 ARG ARG Q . n +Q 1 255 HIS 255 255 255 HIS HIS Q . n +Q 1 256 MET 256 256 256 MET MET Q . n +Q 1 257 SER 257 257 257 SER SER Q . n +Q 1 258 VAL 258 258 ? ? ? Q . n +Q 1 259 PRO 259 259 ? ? ? Q . n +Q 1 260 PRO 260 260 ? ? ? Q . n +Q 1 261 GLU 261 261 ? ? ? Q . n +Q 1 262 SER 262 262 ? ? ? Q . n +R 1 1 CYS 1 1 ? ? ? R . n +R 1 2 LEU 2 2 2 LEU LEU R . n +R 1 3 THR 3 3 3 THR THR R . n +R 1 4 ALA 4 4 4 ALA ALA R . n +R 1 5 PRO 5 5 5 PRO PRO R . n +R 1 6 PRO 6 6 6 PRO PRO R . n +R 1 7 LYS 7 7 7 LYS LYS R . n +R 1 8 GLU 8 8 8 GLU GLU R . n +R 1 9 ALA 9 9 9 ALA ALA R . n +R 1 10 ALA 10 10 10 ALA ALA R . n +R 1 11 ARG 11 11 11 ARG ARG R . n +R 1 12 PRO 12 12 12 PRO PRO R . n +R 1 13 THR 13 13 13 THR THR R . n +R 1 14 LEU 14 14 14 LEU LEU R . n +R 1 15 MET 15 15 15 MET MET R . n +R 1 16 PRO 16 16 16 PRO PRO R . n +R 1 17 ARG 17 17 17 ARG ARG R . n +R 1 18 ALA 18 18 18 ALA ALA R . n +R 1 19 GLN 19 19 19 GLN GLN R . n +R 1 20 SER 20 20 20 SER SER R . n +R 1 21 TYR 21 21 21 TYR TYR R . n +R 1 22 LYS 22 22 22 LYS LYS R . n +R 1 23 ASP 23 23 23 ASP ASP R . n +R 1 24 LEU 24 24 24 LEU LEU R . n +R 1 25 THR 25 25 25 THR THR R . n +R 1 26 HIS 26 26 26 HIS HIS R . n +R 1 27 LEU 27 27 27 LEU LEU R . n +R 1 28 PRO 28 28 28 PRO PRO R . n +R 1 29 ALA 29 29 29 ALA ALA R . n +R 1 30 PRO 30 30 30 PRO PRO R . n +R 1 31 THR 31 31 31 THR THR R . n +R 1 32 GLY 32 32 32 GLY GLY R . n +R 1 33 LYS 33 33 33 LYS LYS R . n +R 1 34 ILE 34 34 34 ILE ILE R . n +R 1 35 PHE 35 35 35 PHE PHE R . n +R 1 36 VAL 36 36 36 VAL VAL R . n +R 1 37 SER 37 37 37 SER SER R . n +R 1 38 VAL 38 38 38 VAL VAL R . n +R 1 39 TYR 39 39 39 TYR TYR R . n +R 1 40 ASN 40 40 40 ASN ASN R . n +R 1 41 ILE 41 41 41 ILE ILE R . n +R 1 42 GLN 42 42 42 GLN GLN R . n +R 1 43 ASP 43 43 43 ASP ASP R . n +R 1 44 GLU 44 44 44 GLU GLU R . n +R 1 45 THR 45 45 45 THR THR R . n +R 1 46 GLY 46 46 46 GLY GLY R . n +R 1 47 GLN 47 47 47 GLN GLN R . n +R 1 48 PHE 48 48 48 PHE PHE R . n +R 1 49 LYS 49 49 49 LYS LYS R . n +R 1 50 PRO 50 50 50 PRO PRO R . n +R 1 51 TYR 51 51 51 TYR TYR R . n +R 1 52 PRO 52 52 52 PRO PRO R . n +R 1 53 ALA 53 53 53 ALA ALA R . n +R 1 54 SER 54 54 54 SER SER R . n +R 1 55 ASN 55 55 55 ASN ASN R . n +R 1 56 PHE 56 56 56 PHE PHE R . n +R 1 57 SER 57 57 57 SER SER R . n +R 1 58 THR 58 58 58 THR THR R . n +R 1 59 ALA 59 59 59 ALA ALA R . n +R 1 60 VAL 60 60 60 VAL VAL R . n +R 1 61 PRO 61 61 61 PRO PRO R . n +R 1 62 GLN 62 62 62 GLN GLN R . n +R 1 63 SER 63 63 63 SER SER R . n +R 1 64 ALA 64 64 64 ALA ALA R . n +R 1 65 THR 65 65 65 THR THR R . n +R 1 66 ALA 66 66 66 ALA ALA R . n +R 1 67 MET 67 67 67 MET MET R . n +R 1 68 LEU 68 68 68 LEU LEU R . n +R 1 69 VAL 69 69 69 VAL VAL R . n +R 1 70 THR 70 70 70 THR THR R . n +R 1 71 ALA 71 71 71 ALA ALA R . n +R 1 72 LEU 72 72 72 LEU LEU R . n +R 1 73 LYS 73 73 73 LYS LYS R . n +R 1 74 ASP 74 74 74 ASP ASP R . n +R 1 75 SER 75 75 75 SER SER R . n +R 1 76 ARG 76 76 76 ARG ARG R . n +R 1 77 TRP 77 77 77 TRP TRP R . n +R 1 78 PHE 78 78 78 PHE PHE R . n +R 1 79 ILE 79 79 79 ILE ILE R . n +R 1 80 PRO 80 80 80 PRO PRO R . n +R 1 81 LEU 81 81 81 LEU LEU R . n +R 1 82 GLU 82 82 82 GLU GLU R . n +R 1 83 ARG 83 83 83 ARG ARG R . n +R 1 84 GLN 84 84 84 GLN GLN R . n +R 1 85 GLY 85 85 85 GLY GLY R . n +R 1 86 LEU 86 86 86 LEU LEU R . n +R 1 87 GLN 87 87 87 GLN GLN R . n +R 1 88 ASN 88 88 88 ASN ASN R . n +R 1 89 LEU 89 89 89 LEU LEU R . n +R 1 90 LEU 90 90 90 LEU LEU R . n +R 1 91 ASN 91 91 91 ASN ASN R . n +R 1 92 GLU 92 92 92 GLU GLU R . n +R 1 93 ARG 93 93 93 ARG ARG R . n +R 1 94 LYS 94 94 94 LYS LYS R . n +R 1 95 ILE 95 95 95 ILE ILE R . n +R 1 96 ILE 96 96 96 ILE ILE R . n +R 1 97 ARG 97 97 97 ARG ARG R . n +R 1 98 ALA 98 98 98 ALA ALA R . n +R 1 99 ALA 99 99 99 ALA ALA R . n +R 1 100 GLN 100 100 100 GLN GLN R . n +R 1 101 GLU 101 101 101 GLU GLU R . n +R 1 102 ASN 102 102 102 ASN ASN R . n +R 1 103 GLY 103 103 103 GLY GLY R . n +R 1 104 THR 104 104 104 THR THR R . n +R 1 105 VAL 105 105 105 VAL VAL R . n +R 1 106 ALA 106 106 106 ALA ALA R . n +R 1 107 ILE 107 107 107 ILE ILE R . n +R 1 108 ASN 108 108 108 ASN ASN R . n +R 1 109 ASN 109 109 109 ASN ASN R . n +R 1 110 ARG 110 110 110 ARG ARG R . n +R 1 111 ILE 111 111 111 ILE ILE R . n +R 1 112 PRO 112 112 112 PRO PRO R . n +R 1 113 LEU 113 113 113 LEU LEU R . n +R 1 114 GLN 114 114 114 GLN GLN R . n +R 1 115 SER 115 115 115 SER SER R . n +R 1 116 LEU 116 116 116 LEU LEU R . n +R 1 117 THR 117 117 117 THR THR R . n +R 1 118 ALA 118 118 118 ALA ALA R . n +R 1 119 ALA 119 119 119 ALA ALA R . n +R 1 120 ASN 120 120 120 ASN ASN R . n +R 1 121 ILE 121 121 121 ILE ILE R . n +R 1 122 MET 122 122 122 MET MET R . n +R 1 123 VAL 123 123 123 VAL VAL R . n +R 1 124 GLU 124 124 124 GLU GLU R . n +R 1 125 GLY 125 125 125 GLY GLY R . n +R 1 126 SER 126 126 126 SER SER R . n +R 1 127 ILE 127 127 127 ILE ILE R . n +R 1 128 ILE 128 128 128 ILE ILE R . n +R 1 129 GLY 129 129 129 GLY GLY R . n +R 1 130 TYR 130 130 130 TYR TYR R . n +R 1 131 GLU 131 131 131 GLU GLU R . n +R 1 132 SER 132 132 132 SER SER R . n +R 1 133 ASN 133 133 133 ASN ASN R . n +R 1 134 VAL 134 134 134 VAL VAL R . n +R 1 135 LYS 135 135 135 LYS LYS R . n +R 1 136 SER 136 136 136 SER SER R . n +R 1 137 GLY 137 137 137 GLY GLY R . n +R 1 138 GLY 138 138 138 GLY GLY R . n +R 1 139 VAL 139 139 139 VAL VAL R . n +R 1 140 GLY 140 140 140 GLY GLY R . n +R 1 141 ALA 141 141 141 ALA ALA R . n +R 1 142 ARG 142 142 142 ARG ARG R . n +R 1 143 TYR 143 143 143 TYR TYR R . n +R 1 144 PHE 144 144 ? ? ? R . n +R 1 145 GLY 145 145 145 GLY GLY R . n +R 1 146 ILE 146 146 146 ILE ILE R . n +R 1 147 GLY 147 147 147 GLY GLY R . n +R 1 148 ALA 148 148 148 ALA ALA R . n +R 1 149 ASP 149 149 149 ASP ASP R . n +R 1 150 THR 150 150 150 THR THR R . n +R 1 151 GLN 151 151 151 GLN GLN R . n +R 1 152 TYR 152 152 152 TYR TYR R . n +R 1 153 GLN 153 153 153 GLN GLN R . n +R 1 154 LEU 154 154 154 LEU LEU R . n +R 1 155 ASP 155 155 155 ASP ASP R . n +R 1 156 GLN 156 156 156 GLN GLN R . n +R 1 157 ILE 157 157 157 ILE ILE R . n +R 1 158 ALA 158 158 158 ALA ALA R . n +R 1 159 VAL 159 159 159 VAL VAL R . n +R 1 160 ASN 160 160 160 ASN ASN R . n +R 1 161 LEU 161 161 161 LEU LEU R . n +R 1 162 ARG 162 162 162 ARG ARG R . n +R 1 163 VAL 163 163 163 VAL VAL R . n +R 1 164 VAL 164 164 164 VAL VAL R . n +R 1 165 ASN 165 165 165 ASN ASN R . n +R 1 166 VAL 166 166 166 VAL VAL R . n +R 1 167 SER 167 167 167 SER SER R . n +R 1 168 THR 168 168 168 THR THR R . n +R 1 169 GLY 169 169 169 GLY GLY R . n +R 1 170 GLU 170 170 170 GLU GLU R . n +R 1 171 ILE 171 171 171 ILE ILE R . n +R 1 172 LEU 172 172 172 LEU LEU R . n +R 1 173 SER 173 173 173 SER SER R . n +R 1 174 SER 174 174 174 SER SER R . n +R 1 175 VAL 175 175 175 VAL VAL R . n +R 1 176 ASN 176 176 176 ASN ASN R . n +R 1 177 THR 177 177 177 THR THR R . n +R 1 178 SER 178 178 178 SER SER R . n +R 1 179 LYS 179 179 179 LYS LYS R . n +R 1 180 THR 180 180 180 THR THR R . n +R 1 181 ILE 181 181 181 ILE ILE R . n +R 1 182 LEU 182 182 182 LEU LEU R . n +R 1 183 SER 183 183 183 SER SER R . n +R 1 184 TYR 184 184 184 TYR TYR R . n +R 1 185 GLU 185 185 185 GLU GLU R . n +R 1 186 VAL 186 186 186 VAL VAL R . n +R 1 187 GLN 187 187 187 GLN GLN R . n +R 1 188 ALA 188 188 188 ALA ALA R . n +R 1 189 GLY 189 189 189 GLY GLY R . n +R 1 190 VAL 190 190 190 VAL VAL R . n +R 1 191 PHE 191 191 191 PHE PHE R . n +R 1 192 ARG 192 192 ? ? ? R . n +R 1 193 PHE 193 193 ? ? ? R . n +R 1 194 ILE 194 194 ? ? ? R . n +R 1 195 ASP 195 195 ? ? ? R . n +R 1 196 TYR 196 196 ? ? ? R . n +R 1 197 GLN 197 197 ? ? ? R . n +R 1 198 ARG 198 198 ? ? ? R . n +R 1 199 LEU 199 199 ? ? ? R . n +R 1 200 LEU 200 200 200 LEU LEU R . n +R 1 201 GLU 201 201 201 GLU GLU R . n +R 1 202 GLY 202 202 202 GLY GLY R . n +R 1 203 GLU 203 203 203 GLU GLU R . n +R 1 204 VAL 204 204 204 VAL VAL R . n +R 1 205 GLY 205 205 205 GLY GLY R . n +R 1 206 TYR 206 206 206 TYR TYR R . n +R 1 207 THR 207 207 207 THR THR R . n +R 1 208 SER 208 208 208 SER SER R . n +R 1 209 ASN 209 209 209 ASN ASN R . n +R 1 210 GLU 210 210 210 GLU GLU R . n +R 1 211 PRO 211 211 211 PRO PRO R . n +R 1 212 VAL 212 212 212 VAL VAL R . n +R 1 213 MET 213 213 213 MET MET R . n +R 1 214 LEU 214 214 214 LEU LEU R . n +R 1 215 CYS 215 215 215 CYS CYS R . n +R 1 216 LEU 216 216 216 LEU LEU R . n +R 1 217 MET 217 217 217 MET MET R . n +R 1 218 SER 218 218 218 SER SER R . n +R 1 219 ALA 219 219 219 ALA ALA R . n +R 1 220 ILE 220 220 220 ILE ILE R . n +R 1 221 GLU 221 221 221 GLU GLU R . n +R 1 222 THR 222 222 222 THR THR R . n +R 1 223 GLY 223 223 223 GLY GLY R . n +R 1 224 VAL 224 224 224 VAL VAL R . n +R 1 225 ILE 225 225 225 ILE ILE R . n +R 1 226 PHE 226 226 226 PHE PHE R . n +R 1 227 LEU 227 227 227 LEU LEU R . n +R 1 228 ILE 228 228 228 ILE ILE R . n +R 1 229 ASN 229 229 229 ASN ASN R . n +R 1 230 ASP 230 230 230 ASP ASP R . n +R 1 231 GLY 231 231 231 GLY GLY R . n +R 1 232 ILE 232 232 232 ILE ILE R . n +R 1 233 ASP 233 233 233 ASP ASP R . n +R 1 234 ARG 234 234 234 ARG ARG R . n +R 1 235 GLY 235 235 235 GLY GLY R . n +R 1 236 LEU 236 236 236 LEU LEU R . n +R 1 237 TRP 237 237 237 TRP TRP R . n +R 1 238 ASP 238 238 238 ASP ASP R . n +R 1 239 LEU 239 239 239 LEU LEU R . n +R 1 240 GLN 240 240 240 GLN GLN R . n +R 1 241 ASN 241 241 241 ASN ASN R . n +R 1 242 LYS 242 242 242 LYS LYS R . n +R 1 243 ALA 243 243 243 ALA ALA R . n +R 1 244 GLU 244 244 244 GLU GLU R . n +R 1 245 ARG 245 245 245 ARG ARG R . n +R 1 246 GLN 246 246 246 GLN GLN R . n +R 1 247 ASN 247 247 247 ASN ASN R . n +R 1 248 ASP 248 248 248 ASP ASP R . n +R 1 249 ILE 249 249 249 ILE ILE R . n +R 1 250 LEU 250 250 250 LEU LEU R . n +R 1 251 VAL 251 251 251 VAL VAL R . n +R 1 252 LYS 252 252 252 LYS LYS R . n +R 1 253 TYR 253 253 253 TYR TYR R . n +R 1 254 ARG 254 254 254 ARG ARG R . n +R 1 255 HIS 255 255 255 HIS HIS R . n +R 1 256 MET 256 256 256 MET MET R . n +R 1 257 SER 257 257 257 SER SER R . n +R 1 258 VAL 258 258 ? ? ? R . n +R 1 259 PRO 259 259 ? ? ? R . n +R 1 260 PRO 260 260 ? ? ? R . n +R 1 261 GLU 261 261 ? ? ? R . n +R 1 262 SER 262 262 ? ? ? R . n +# +loop_ +_pdbx_struct_assembly.id +_pdbx_struct_assembly.details +_pdbx_struct_assembly.method_details +_pdbx_struct_assembly.oligomeric_details +_pdbx_struct_assembly.oligomeric_count +1 author_and_software_defined_assembly PISA nonameric 9 +2 author_and_software_defined_assembly PISA nonameric 9 +# +loop_ +_pdbx_struct_assembly_gen.assembly_id +_pdbx_struct_assembly_gen.oper_expression +_pdbx_struct_assembly_gen.asym_id_list +1 1 A,B,C,D,E,F,G,H,I +2 1 J,K,L,M,N,O,P,Q,R +# +loop_ +_pdbx_struct_assembly_prop.biol_id +_pdbx_struct_assembly_prop.type +_pdbx_struct_assembly_prop.value +_pdbx_struct_assembly_prop.details +1 'ABSA (A^2)' 56740 ? +1 MORE -256.4 ? +1 'SSA (A^2)' 87290 ? +2 'ABSA (A^2)' 56870 ? +2 MORE -258.5 ? +2 'SSA (A^2)' 86830 ? +# +_pdbx_struct_oper_list.id 1 +_pdbx_struct_oper_list.type 'identity operation' +_pdbx_struct_oper_list.name 1_555 +_pdbx_struct_oper_list.symmetry_operation x,y,z +_pdbx_struct_oper_list.matrix[1][1] 1.0000000000 +_pdbx_struct_oper_list.matrix[1][2] 0.0000000000 +_pdbx_struct_oper_list.matrix[1][3] 0.0000000000 +_pdbx_struct_oper_list.vector[1] 0.0000000000 +_pdbx_struct_oper_list.matrix[2][1] 0.0000000000 +_pdbx_struct_oper_list.matrix[2][2] 1.0000000000 +_pdbx_struct_oper_list.matrix[2][3] 0.0000000000 +_pdbx_struct_oper_list.vector[2] 0.0000000000 +_pdbx_struct_oper_list.matrix[3][1] 0.0000000000 +_pdbx_struct_oper_list.matrix[3][2] 0.0000000000 +_pdbx_struct_oper_list.matrix[3][3] 1.0000000000 +_pdbx_struct_oper_list.vector[3] 0.0000000000 +# +loop_ +_pdbx_audit_revision_history.ordinal +_pdbx_audit_revision_history.data_content_type +_pdbx_audit_revision_history.major_revision +_pdbx_audit_revision_history.minor_revision +_pdbx_audit_revision_history.revision_date +1 'Structure model' 1 0 2014-09-24 +2 'Structure model' 1 1 2014-12-17 +# +_pdbx_audit_revision_details.ordinal 1 +_pdbx_audit_revision_details.revision_ordinal 1 +_pdbx_audit_revision_details.data_content_type 'Structure model' +_pdbx_audit_revision_details.provider repository +_pdbx_audit_revision_details.type 'Initial release' +_pdbx_audit_revision_details.description ? +# +_pdbx_audit_revision_group.ordinal 1 +_pdbx_audit_revision_group.revision_ordinal 2 +_pdbx_audit_revision_group.data_content_type 'Structure model' +_pdbx_audit_revision_group.group 'Database references' +# +loop_ +_software.name +_software.classification +_software.version +_software.citation_id +_software.pdbx_ordinal +REFMAC refinement 5.7.0029 ? 1 +XDS 'data reduction' . ? 2 +XSCALE 'data scaling' . ? 3 +PHASER phasing . ? 4 +# +_pdbx_database_remark.id 700 +_pdbx_database_remark.text +; +SHEET +THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN +ORDER TO REPRESENT THIS FEATURE IN THE SHEET RECORDS BELOW, +TWO SHEETS ARE DEFINED. +; +# +_pdbx_entry_details.entry_id 4UV3 +_pdbx_entry_details.compound_details ? +_pdbx_entry_details.source_details ? +_pdbx_entry_details.nonpolymer_details ? +_pdbx_entry_details.sequence_details 'MATURE CSGG, MEMBRANE FORM' +# +loop_ +_pdbx_validate_close_contact.id +_pdbx_validate_close_contact.PDB_model_num +_pdbx_validate_close_contact.auth_atom_id_1 +_pdbx_validate_close_contact.auth_asym_id_1 +_pdbx_validate_close_contact.auth_comp_id_1 +_pdbx_validate_close_contact.auth_seq_id_1 +_pdbx_validate_close_contact.PDB_ins_code_1 +_pdbx_validate_close_contact.label_alt_id_1 +_pdbx_validate_close_contact.auth_atom_id_2 +_pdbx_validate_close_contact.auth_asym_id_2 +_pdbx_validate_close_contact.auth_comp_id_2 +_pdbx_validate_close_contact.auth_seq_id_2 +_pdbx_validate_close_contact.PDB_ins_code_2 +_pdbx_validate_close_contact.label_alt_id_2 +_pdbx_validate_close_contact.dist +1 1 NH2 F ARG 162 ? ? OE1 G GLU 82 ? ? 2.03 +2 1 OD2 L ASP 233 ? ? NH2 L ARG 254 ? ? 2.03 +3 1 OE2 A GLU 92 ? ? NE I ARG 83 ? ? 2.14 +4 1 N B GLY 145 ? ? O B PHE 191 ? ? 2.18 +5 1 NE K ARG 83 ? ? OE2 L GLU 92 ? ? 2.18 +# +loop_ +_pdbx_validate_torsion.id +_pdbx_validate_torsion.PDB_model_num +_pdbx_validate_torsion.auth_comp_id +_pdbx_validate_torsion.auth_asym_id +_pdbx_validate_torsion.auth_seq_id +_pdbx_validate_torsion.PDB_ins_code +_pdbx_validate_torsion.label_alt_id +_pdbx_validate_torsion.phi +_pdbx_validate_torsion.psi +1 1 THR A 3 ? ? -142.29 -6.27 +2 1 ALA A 10 ? ? 85.66 156.72 +3 1 PRO A 16 ? ? -63.74 82.91 +4 1 ALA A 18 ? ? -113.23 -119.53 +5 1 HIS A 26 ? ? -83.68 37.37 +6 1 ASN A 40 ? ? -170.36 133.34 +7 1 GLU A 44 ? ? -67.06 10.86 +8 1 GLN A 62 ? ? -89.77 40.60 +9 1 ILE A 128 ? ? -95.56 42.29 +10 1 THR A 168 ? ? -136.66 -38.27 +11 1 SER A 173 ? ? -172.19 129.01 +12 1 THR B 3 ? ? -141.82 -6.29 +13 1 ALA B 10 ? ? 84.83 158.85 +14 1 ALA B 18 ? ? -112.51 -120.14 +15 1 HIS B 26 ? ? -84.34 37.00 +16 1 ASN B 40 ? ? -170.89 134.88 +17 1 GLN B 62 ? ? -88.20 37.67 +18 1 ILE B 128 ? ? -97.16 42.39 +19 1 THR B 168 ? ? -139.98 -35.67 +20 1 SER B 173 ? ? -171.29 133.31 +21 1 ALA C 10 ? ? 84.13 158.67 +22 1 PRO C 16 ? ? -67.32 82.69 +23 1 ALA C 18 ? ? -113.30 -118.84 +24 1 HIS C 26 ? ? -84.52 36.55 +25 1 GLU C 44 ? ? -68.75 16.62 +26 1 GLN C 62 ? ? -88.07 35.25 +27 1 THR C 168 ? ? -137.90 -34.62 +28 1 SER C 173 ? ? -171.16 133.66 +29 1 ALA D 10 ? ? 83.31 158.10 +30 1 PRO D 16 ? ? -64.42 81.10 +31 1 ALA D 18 ? ? -113.33 -118.53 +32 1 HIS D 26 ? ? -84.88 37.09 +33 1 GLU D 44 ? ? -67.52 16.32 +34 1 GLN D 62 ? ? -91.90 35.50 +35 1 THR D 168 ? ? -137.35 -35.71 +36 1 SER D 173 ? ? -170.49 134.37 +37 1 THR E 3 ? ? -141.59 -3.58 +38 1 ALA E 10 ? ? 83.47 157.08 +39 1 PRO E 16 ? ? -59.21 79.70 +40 1 ALA E 18 ? ? -113.11 -116.56 +41 1 HIS E 26 ? ? -85.31 36.92 +42 1 GLU E 44 ? ? -66.79 15.23 +43 1 GLN E 62 ? ? -87.92 33.72 +44 1 THR E 168 ? ? -140.02 -35.42 +45 1 THR F 3 ? ? -151.40 -1.48 +46 1 ALA F 10 ? ? 83.02 157.10 +47 1 PRO F 16 ? ? -63.52 82.24 +48 1 ALA F 18 ? ? -111.16 -117.74 +49 1 HIS F 26 ? ? -83.07 33.44 +50 1 GLN F 62 ? ? -87.99 34.10 +51 1 THR F 168 ? ? -141.87 -33.46 +52 1 THR G 3 ? ? -141.01 -4.03 +53 1 ALA G 10 ? ? 85.20 159.53 +54 1 PRO G 16 ? ? -64.46 82.82 +55 1 ALA G 18 ? ? -110.41 -119.73 +56 1 HIS G 26 ? ? -84.36 36.02 +57 1 GLN G 62 ? ? -85.83 33.74 +58 1 THR G 168 ? ? -136.54 -30.34 +59 1 SER G 173 ? ? -170.69 134.18 +60 1 ALA H 10 ? ? 87.04 155.37 +61 1 PRO H 16 ? ? -63.06 78.32 +62 1 ALA H 18 ? ? -113.40 -119.94 +63 1 HIS H 26 ? ? -84.47 36.40 +64 1 GLN H 62 ? ? -88.66 35.74 +65 1 THR H 168 ? ? -135.51 -32.61 +66 1 SER H 173 ? ? -173.79 133.11 +67 1 THR I 3 ? ? -141.03 -4.52 +68 1 ALA I 10 ? ? 84.66 154.51 +69 1 PRO I 16 ? ? -64.60 82.21 +70 1 ALA I 18 ? ? -113.43 -119.40 +71 1 HIS I 26 ? ? -84.09 36.24 +72 1 GLU I 44 ? ? -68.18 14.85 +73 1 GLN I 62 ? ? -91.64 36.90 +74 1 THR I 168 ? ? -135.42 -30.57 +75 1 SER I 173 ? ? -172.65 132.94 +76 1 ALA J 10 ? ? 85.89 155.94 +77 1 PRO J 16 ? ? -62.11 80.00 +78 1 ALA J 18 ? ? -113.69 -119.38 +79 1 HIS J 26 ? ? -84.37 36.09 +80 1 GLN J 62 ? ? -89.00 36.73 +81 1 THR J 168 ? ? -135.16 -33.00 +82 1 SER J 173 ? ? -173.31 132.60 +83 1 THR K 3 ? ? -141.72 -6.89 +84 1 ALA K 10 ? ? 84.22 154.85 +85 1 PRO K 16 ? ? -65.67 82.56 +86 1 ALA K 18 ? ? -114.32 -119.74 +87 1 HIS K 26 ? ? -83.89 36.44 +88 1 GLU K 44 ? ? -67.69 12.96 +89 1 GLN K 62 ? ? -90.30 37.31 +90 1 THR K 168 ? ? -133.44 -30.84 +91 1 SER K 173 ? ? -173.11 131.46 +92 1 THR L 3 ? ? -142.74 -4.36 +93 1 ALA L 10 ? ? 86.00 155.10 +94 1 PRO L 16 ? ? -64.21 84.46 +95 1 ALA L 18 ? ? -112.27 -119.83 +96 1 HIS L 26 ? ? -84.19 37.16 +97 1 ASN L 40 ? ? -170.54 133.03 +98 1 GLU L 44 ? ? -66.65 9.81 +99 1 GLN L 62 ? ? -92.73 39.52 +100 1 THR L 168 ? ? -137.81 -37.37 +101 1 SER L 173 ? ? -173.68 130.00 +102 1 THR M 3 ? ? -142.47 -6.07 +103 1 ALA M 10 ? ? 84.11 159.38 +104 1 PRO M 16 ? ? -65.04 84.02 +105 1 ALA M 18 ? ? -113.48 -119.39 +106 1 HIS M 26 ? ? -84.59 36.62 +107 1 ASN M 40 ? ? -171.40 134.08 +108 1 GLN M 62 ? ? -87.19 35.25 +109 1 THR M 168 ? ? -139.14 -36.56 +110 1 SER M 173 ? ? -173.26 131.57 +111 1 THR N 3 ? ? -140.37 -4.87 +112 1 ALA N 10 ? ? 83.13 163.26 +113 1 PRO N 16 ? ? -66.10 83.61 +114 1 ALA N 18 ? ? -113.51 -118.93 +115 1 HIS N 26 ? ? -84.46 36.33 +116 1 GLU N 44 ? ? -68.23 15.99 +117 1 GLN N 62 ? ? -89.04 35.64 +118 1 THR N 168 ? ? -137.18 -34.77 +119 1 SER N 173 ? ? -170.34 134.20 +120 1 ASN N 247 ? ? -38.99 137.68 +121 1 ALA O 10 ? ? 83.35 158.62 +122 1 PRO O 16 ? ? -66.69 82.12 +123 1 ALA O 18 ? ? -113.68 -118.52 +124 1 HIS O 26 ? ? -85.57 37.41 +125 1 GLU O 44 ? ? -68.29 17.52 +126 1 GLN O 62 ? ? -89.52 34.76 +127 1 THR O 168 ? ? -136.53 -35.96 +128 1 SER O 173 ? ? -170.11 133.37 +129 1 ALA P 10 ? ? 84.32 157.52 +130 1 PRO P 16 ? ? -62.79 81.54 +131 1 ALA P 18 ? ? -113.42 -117.54 +132 1 HIS P 26 ? ? -84.72 36.45 +133 1 GLU P 44 ? ? -65.96 16.27 +134 1 GLN P 62 ? ? -87.90 34.17 +135 1 THR P 168 ? ? -140.35 -34.50 +136 1 THR Q 3 ? ? -140.76 -4.29 +137 1 ALA Q 10 ? ? 86.33 158.98 +138 1 PRO Q 16 ? ? -62.74 82.24 +139 1 ALA Q 18 ? ? -111.75 -118.36 +140 1 HIS Q 26 ? ? -83.97 35.50 +141 1 GLN Q 62 ? ? -88.61 33.55 +142 1 THR Q 168 ? ? -140.09 -33.26 +143 1 THR R 3 ? ? -140.38 -4.26 +144 1 ALA R 10 ? ? 84.17 160.80 +145 1 PRO R 16 ? ? -66.18 83.45 +146 1 ALA R 18 ? ? -110.09 -118.62 +147 1 HIS R 26 ? ? -83.76 35.87 +148 1 GLN R 62 ? ? -85.40 33.36 +149 1 ARG R 83 ? ? -152.93 -16.09 +150 1 THR R 168 ? ? -138.28 -30.65 +151 1 SER R 173 ? ? -170.36 134.04 +# +loop_ +_pdbx_validate_peptide_omega.id +_pdbx_validate_peptide_omega.PDB_model_num +_pdbx_validate_peptide_omega.auth_comp_id_1 +_pdbx_validate_peptide_omega.auth_asym_id_1 +_pdbx_validate_peptide_omega.auth_seq_id_1 +_pdbx_validate_peptide_omega.PDB_ins_code_1 +_pdbx_validate_peptide_omega.label_alt_id_1 +_pdbx_validate_peptide_omega.auth_comp_id_2 +_pdbx_validate_peptide_omega.auth_asym_id_2 +_pdbx_validate_peptide_omega.auth_seq_id_2 +_pdbx_validate_peptide_omega.PDB_ins_code_2 +_pdbx_validate_peptide_omega.label_alt_id_2 +_pdbx_validate_peptide_omega.omega +1 1 LEU E 14 ? ? MET E 15 ? ? -149.58 +2 1 LEU L 14 ? ? MET L 15 ? ? -149.95 +3 1 LEU P 14 ? ? MET P 15 ? ? -149.08 +4 1 PHE R 78 ? ? ILE R 79 ? ? 149.51 +# +loop_ +_pdbx_unobs_or_zero_occ_residues.id +_pdbx_unobs_or_zero_occ_residues.PDB_model_num +_pdbx_unobs_or_zero_occ_residues.polymer_flag +_pdbx_unobs_or_zero_occ_residues.occupancy_flag +_pdbx_unobs_or_zero_occ_residues.auth_asym_id +_pdbx_unobs_or_zero_occ_residues.auth_comp_id +_pdbx_unobs_or_zero_occ_residues.auth_seq_id +_pdbx_unobs_or_zero_occ_residues.PDB_ins_code +_pdbx_unobs_or_zero_occ_residues.label_asym_id +_pdbx_unobs_or_zero_occ_residues.label_comp_id +_pdbx_unobs_or_zero_occ_residues.label_seq_id +1 1 Y 1 A CYS 1 ? A CYS 1 +2 1 Y 1 A PHE 144 ? A PHE 144 +3 1 Y 1 A PHE 193 ? A PHE 193 +4 1 Y 1 A ILE 194 ? A ILE 194 +5 1 Y 1 A ASP 195 ? A ASP 195 +6 1 Y 1 A TYR 196 ? A TYR 196 +7 1 Y 1 A GLN 197 ? A GLN 197 +8 1 Y 1 A ARG 198 ? A ARG 198 +9 1 Y 1 A LEU 199 ? A LEU 199 +10 1 Y 1 A VAL 258 ? A VAL 258 +11 1 Y 1 A PRO 259 ? A PRO 259 +12 1 Y 1 A PRO 260 ? A PRO 260 +13 1 Y 1 A GLU 261 ? A GLU 261 +14 1 Y 1 A SER 262 ? A SER 262 +15 1 Y 1 B CYS 1 ? B CYS 1 +16 1 Y 1 B PHE 144 ? B PHE 144 +17 1 Y 1 B PHE 193 ? B PHE 193 +18 1 Y 1 B ILE 194 ? B ILE 194 +19 1 Y 1 B ASP 195 ? B ASP 195 +20 1 Y 1 B TYR 196 ? B TYR 196 +21 1 Y 1 B GLN 197 ? B GLN 197 +22 1 Y 1 B ARG 198 ? B ARG 198 +23 1 Y 1 B LEU 199 ? B LEU 199 +24 1 Y 1 B VAL 258 ? B VAL 258 +25 1 Y 1 B PRO 259 ? B PRO 259 +26 1 Y 1 B PRO 260 ? B PRO 260 +27 1 Y 1 B GLU 261 ? B GLU 261 +28 1 Y 1 B SER 262 ? B SER 262 +29 1 Y 1 C CYS 1 ? C CYS 1 +30 1 Y 1 C PHE 144 ? C PHE 144 +31 1 Y 1 C ARG 192 ? C ARG 192 +32 1 Y 1 C PHE 193 ? C PHE 193 +33 1 Y 1 C ILE 194 ? C ILE 194 +34 1 Y 1 C ASP 195 ? C ASP 195 +35 1 Y 1 C TYR 196 ? C TYR 196 +36 1 Y 1 C GLN 197 ? C GLN 197 +37 1 Y 1 C ARG 198 ? C ARG 198 +38 1 Y 1 C LEU 199 ? C LEU 199 +39 1 Y 1 C VAL 258 ? C VAL 258 +40 1 Y 1 C PRO 259 ? C PRO 259 +41 1 Y 1 C PRO 260 ? C PRO 260 +42 1 Y 1 C GLU 261 ? C GLU 261 +43 1 Y 1 C SER 262 ? C SER 262 +44 1 Y 1 D CYS 1 ? D CYS 1 +45 1 Y 1 D PHE 144 ? D PHE 144 +46 1 Y 1 D PHE 193 ? D PHE 193 +47 1 Y 1 D ILE 194 ? D ILE 194 +48 1 Y 1 D ASP 195 ? D ASP 195 +49 1 Y 1 D TYR 196 ? D TYR 196 +50 1 Y 1 D GLN 197 ? D GLN 197 +51 1 Y 1 D ARG 198 ? D ARG 198 +52 1 Y 1 D LEU 199 ? D LEU 199 +53 1 Y 1 D VAL 258 ? D VAL 258 +54 1 Y 1 D PRO 259 ? D PRO 259 +55 1 Y 1 D PRO 260 ? D PRO 260 +56 1 Y 1 D GLU 261 ? D GLU 261 +57 1 Y 1 D SER 262 ? D SER 262 +58 1 Y 1 E CYS 1 ? E CYS 1 +59 1 Y 1 E PHE 144 ? E PHE 144 +60 1 Y 1 E ARG 192 ? E ARG 192 +61 1 Y 1 E PHE 193 ? E PHE 193 +62 1 Y 1 E ILE 194 ? E ILE 194 +63 1 Y 1 E ASP 195 ? E ASP 195 +64 1 Y 1 E TYR 196 ? E TYR 196 +65 1 Y 1 E GLN 197 ? E GLN 197 +66 1 Y 1 E ARG 198 ? E ARG 198 +67 1 Y 1 E LEU 199 ? E LEU 199 +68 1 Y 1 E VAL 258 ? E VAL 258 +69 1 Y 1 E PRO 259 ? E PRO 259 +70 1 Y 1 E PRO 260 ? E PRO 260 +71 1 Y 1 E GLU 261 ? E GLU 261 +72 1 Y 1 E SER 262 ? E SER 262 +73 1 Y 1 F CYS 1 ? F CYS 1 +74 1 Y 1 F PHE 144 ? F PHE 144 +75 1 Y 1 F ARG 192 ? F ARG 192 +76 1 Y 1 F PHE 193 ? F PHE 193 +77 1 Y 1 F ILE 194 ? F ILE 194 +78 1 Y 1 F ASP 195 ? F ASP 195 +79 1 Y 1 F TYR 196 ? F TYR 196 +80 1 Y 1 F GLN 197 ? F GLN 197 +81 1 Y 1 F ARG 198 ? F ARG 198 +82 1 Y 1 F LEU 199 ? F LEU 199 +83 1 Y 1 F VAL 258 ? F VAL 258 +84 1 Y 1 F PRO 259 ? F PRO 259 +85 1 Y 1 F PRO 260 ? F PRO 260 +86 1 Y 1 F GLU 261 ? F GLU 261 +87 1 Y 1 F SER 262 ? F SER 262 +88 1 Y 1 G CYS 1 ? G CYS 1 +89 1 Y 1 G PHE 144 ? G PHE 144 +90 1 Y 1 G ARG 192 ? G ARG 192 +91 1 Y 1 G PHE 193 ? G PHE 193 +92 1 Y 1 G ILE 194 ? G ILE 194 +93 1 Y 1 G ASP 195 ? G ASP 195 +94 1 Y 1 G TYR 196 ? G TYR 196 +95 1 Y 1 G GLN 197 ? G GLN 197 +96 1 Y 1 G ARG 198 ? G ARG 198 +97 1 Y 1 G LEU 199 ? G LEU 199 +98 1 Y 1 G VAL 258 ? G VAL 258 +99 1 Y 1 G PRO 259 ? G PRO 259 +100 1 Y 1 G PRO 260 ? G PRO 260 +101 1 Y 1 G GLU 261 ? G GLU 261 +102 1 Y 1 G SER 262 ? G SER 262 +103 1 Y 1 H CYS 1 ? H CYS 1 +104 1 Y 1 H PHE 144 ? H PHE 144 +105 1 Y 1 H PHE 193 ? H PHE 193 +106 1 Y 1 H ILE 194 ? H ILE 194 +107 1 Y 1 H ASP 195 ? H ASP 195 +108 1 Y 1 H TYR 196 ? H TYR 196 +109 1 Y 1 H GLN 197 ? H GLN 197 +110 1 Y 1 H ARG 198 ? H ARG 198 +111 1 Y 1 H LEU 199 ? H LEU 199 +112 1 Y 1 H VAL 258 ? H VAL 258 +113 1 Y 1 H PRO 259 ? H PRO 259 +114 1 Y 1 H PRO 260 ? H PRO 260 +115 1 Y 1 H GLU 261 ? H GLU 261 +116 1 Y 1 H SER 262 ? H SER 262 +117 1 Y 1 I CYS 1 ? I CYS 1 +118 1 Y 1 I PHE 144 ? I PHE 144 +119 1 Y 1 I ARG 192 ? I ARG 192 +120 1 Y 1 I PHE 193 ? I PHE 193 +121 1 Y 1 I ILE 194 ? I ILE 194 +122 1 Y 1 I ASP 195 ? I ASP 195 +123 1 Y 1 I TYR 196 ? I TYR 196 +124 1 Y 1 I GLN 197 ? I GLN 197 +125 1 Y 1 I ARG 198 ? I ARG 198 +126 1 Y 1 I LEU 199 ? I LEU 199 +127 1 Y 1 I VAL 258 ? I VAL 258 +128 1 Y 1 I PRO 259 ? I PRO 259 +129 1 Y 1 I PRO 260 ? I PRO 260 +130 1 Y 1 I GLU 261 ? I GLU 261 +131 1 Y 1 I SER 262 ? I SER 262 +132 1 Y 1 J CYS 1 ? J CYS 1 +133 1 Y 1 J PHE 144 ? J PHE 144 +134 1 Y 1 J PHE 193 ? J PHE 193 +135 1 Y 1 J ILE 194 ? J ILE 194 +136 1 Y 1 J ASP 195 ? J ASP 195 +137 1 Y 1 J TYR 196 ? J TYR 196 +138 1 Y 1 J GLN 197 ? J GLN 197 +139 1 Y 1 J ARG 198 ? J ARG 198 +140 1 Y 1 J LEU 199 ? J LEU 199 +141 1 Y 1 J VAL 258 ? J VAL 258 +142 1 Y 1 J PRO 259 ? J PRO 259 +143 1 Y 1 J PRO 260 ? J PRO 260 +144 1 Y 1 J GLU 261 ? J GLU 261 +145 1 Y 1 J SER 262 ? J SER 262 +146 1 Y 1 K CYS 1 ? K CYS 1 +147 1 Y 1 K PHE 144 ? K PHE 144 +148 1 Y 1 K ARG 192 ? K ARG 192 +149 1 Y 1 K PHE 193 ? K PHE 193 +150 1 Y 1 K ILE 194 ? K ILE 194 +151 1 Y 1 K ASP 195 ? K ASP 195 +152 1 Y 1 K TYR 196 ? K TYR 196 +153 1 Y 1 K GLN 197 ? K GLN 197 +154 1 Y 1 K ARG 198 ? K ARG 198 +155 1 Y 1 K LEU 199 ? K LEU 199 +156 1 Y 1 K VAL 258 ? K VAL 258 +157 1 Y 1 K PRO 259 ? K PRO 259 +158 1 Y 1 K PRO 260 ? K PRO 260 +159 1 Y 1 K GLU 261 ? K GLU 261 +160 1 Y 1 K SER 262 ? K SER 262 +161 1 Y 1 L CYS 1 ? L CYS 1 +162 1 Y 1 L PHE 144 ? L PHE 144 +163 1 Y 1 L ARG 192 ? L ARG 192 +164 1 Y 1 L PHE 193 ? L PHE 193 +165 1 Y 1 L ILE 194 ? L ILE 194 +166 1 Y 1 L ASP 195 ? L ASP 195 +167 1 Y 1 L TYR 196 ? L TYR 196 +168 1 Y 1 L GLN 197 ? L GLN 197 +169 1 Y 1 L ARG 198 ? L ARG 198 +170 1 Y 1 L LEU 199 ? L LEU 199 +171 1 Y 1 L VAL 258 ? L VAL 258 +172 1 Y 1 L PRO 259 ? L PRO 259 +173 1 Y 1 L PRO 260 ? L PRO 260 +174 1 Y 1 L GLU 261 ? L GLU 261 +175 1 Y 1 L SER 262 ? L SER 262 +176 1 Y 1 M CYS 1 ? M CYS 1 +177 1 Y 1 M PHE 144 ? M PHE 144 +178 1 Y 1 M ARG 192 ? M ARG 192 +179 1 Y 1 M PHE 193 ? M PHE 193 +180 1 Y 1 M ILE 194 ? M ILE 194 +181 1 Y 1 M ASP 195 ? M ASP 195 +182 1 Y 1 M TYR 196 ? M TYR 196 +183 1 Y 1 M GLN 197 ? M GLN 197 +184 1 Y 1 M ARG 198 ? M ARG 198 +185 1 Y 1 M LEU 199 ? M LEU 199 +186 1 Y 1 M VAL 258 ? M VAL 258 +187 1 Y 1 M PRO 259 ? M PRO 259 +188 1 Y 1 M PRO 260 ? M PRO 260 +189 1 Y 1 M GLU 261 ? M GLU 261 +190 1 Y 1 M SER 262 ? M SER 262 +191 1 Y 1 N CYS 1 ? N CYS 1 +192 1 Y 1 N PHE 144 ? N PHE 144 +193 1 Y 1 N ARG 192 ? N ARG 192 +194 1 Y 1 N PHE 193 ? N PHE 193 +195 1 Y 1 N ILE 194 ? N ILE 194 +196 1 Y 1 N ASP 195 ? N ASP 195 +197 1 Y 1 N TYR 196 ? N TYR 196 +198 1 Y 1 N GLN 197 ? N GLN 197 +199 1 Y 1 N ARG 198 ? N ARG 198 +200 1 Y 1 N LEU 199 ? N LEU 199 +201 1 Y 1 N VAL 258 ? N VAL 258 +202 1 Y 1 N PRO 259 ? N PRO 259 +203 1 Y 1 N PRO 260 ? N PRO 260 +204 1 Y 1 N GLU 261 ? N GLU 261 +205 1 Y 1 N SER 262 ? N SER 262 +206 1 Y 1 O CYS 1 ? O CYS 1 +207 1 Y 1 O PHE 144 ? O PHE 144 +208 1 Y 1 O ARG 192 ? O ARG 192 +209 1 Y 1 O PHE 193 ? O PHE 193 +210 1 Y 1 O ILE 194 ? O ILE 194 +211 1 Y 1 O ASP 195 ? O ASP 195 +212 1 Y 1 O TYR 196 ? O TYR 196 +213 1 Y 1 O GLN 197 ? O GLN 197 +214 1 Y 1 O ARG 198 ? O ARG 198 +215 1 Y 1 O LEU 199 ? O LEU 199 +216 1 Y 1 O VAL 258 ? O VAL 258 +217 1 Y 1 O PRO 259 ? O PRO 259 +218 1 Y 1 O PRO 260 ? O PRO 260 +219 1 Y 1 O GLU 261 ? O GLU 261 +220 1 Y 1 O SER 262 ? O SER 262 +221 1 Y 1 P CYS 1 ? P CYS 1 +222 1 Y 1 P PHE 144 ? P PHE 144 +223 1 Y 1 P ARG 192 ? P ARG 192 +224 1 Y 1 P PHE 193 ? P PHE 193 +225 1 Y 1 P ILE 194 ? P ILE 194 +226 1 Y 1 P ASP 195 ? P ASP 195 +227 1 Y 1 P TYR 196 ? P TYR 196 +228 1 Y 1 P GLN 197 ? P GLN 197 +229 1 Y 1 P ARG 198 ? P ARG 198 +230 1 Y 1 P LEU 199 ? P LEU 199 +231 1 Y 1 P VAL 258 ? P VAL 258 +232 1 Y 1 P PRO 259 ? P PRO 259 +233 1 Y 1 P PRO 260 ? P PRO 260 +234 1 Y 1 P GLU 261 ? P GLU 261 +235 1 Y 1 P SER 262 ? P SER 262 +236 1 Y 1 Q CYS 1 ? Q CYS 1 +237 1 Y 1 Q PHE 144 ? Q PHE 144 +238 1 Y 1 Q ARG 192 ? Q ARG 192 +239 1 Y 1 Q PHE 193 ? Q PHE 193 +240 1 Y 1 Q ILE 194 ? Q ILE 194 +241 1 Y 1 Q ASP 195 ? Q ASP 195 +242 1 Y 1 Q TYR 196 ? Q TYR 196 +243 1 Y 1 Q GLN 197 ? Q GLN 197 +244 1 Y 1 Q ARG 198 ? Q ARG 198 +245 1 Y 1 Q LEU 199 ? Q LEU 199 +246 1 Y 1 Q VAL 258 ? Q VAL 258 +247 1 Y 1 Q PRO 259 ? Q PRO 259 +248 1 Y 1 Q PRO 260 ? Q PRO 260 +249 1 Y 1 Q GLU 261 ? Q GLU 261 +250 1 Y 1 Q SER 262 ? Q SER 262 +251 1 Y 1 R CYS 1 ? R CYS 1 +252 1 Y 1 R PHE 144 ? R PHE 144 +253 1 Y 1 R ARG 192 ? R ARG 192 +254 1 Y 1 R PHE 193 ? R PHE 193 +255 1 Y 1 R ILE 194 ? R ILE 194 +256 1 Y 1 R ASP 195 ? R ASP 195 +257 1 Y 1 R TYR 196 ? R TYR 196 +258 1 Y 1 R GLN 197 ? R GLN 197 +259 1 Y 1 R ARG 198 ? R ARG 198 +260 1 Y 1 R LEU 199 ? R LEU 199 +261 1 Y 1 R VAL 258 ? R VAL 258 +262 1 Y 1 R PRO 259 ? R PRO 259 +263 1 Y 1 R PRO 260 ? R PRO 260 +264 1 Y 1 R GLU 261 ? R GLU 261 +265 1 Y 1 R SER 262 ? R SER 262 +# diff --git a/esm/source/examples/inverse_folding/data/4uv3.pdb b/esm/source/examples/inverse_folding/data/4uv3.pdb new file mode 100644 index 0000000000000000000000000000000000000000..09cea6988c7c773ab5d8cb5baa77e97acae05cf3 --- /dev/null +++ b/esm/source/examples/inverse_folding/data/4uv3.pdb @@ -0,0 +1,35701 @@ +HEADER TRANSPORT PROTEIN 04-AUG-14 4UV3 +TITLE STRUCTURE OF THE CURLI TRANSPORT LIPOPROTEIN CSGG IN ITS +TITLE 2 MEMBRANE-BOUND CONFORMATION +COMPND MOL_ID: 1; +COMPND 2 MOLECULE: CURLI PRODUCTION ASSEMBLY/TRANSPORT COMPONENT CSGG; +COMPND 3 CHAIN: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R; +COMPND 4 ENGINEERED: YES; +COMPND 5 OTHER_DETAILS: LIPOPROTEIN +SOURCE MOL_ID: 1; +SOURCE 2 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI STR. K-12 SUBSTR. MC4100; +SOURCE 3 ORGANISM_TAXID: 1403831; +SOURCE 4 EXPRESSION_SYSTEM: ESCHERICHIA COLI; +SOURCE 5 EXPRESSION_SYSTEM_TAXID: 469008; +SOURCE 6 EXPRESSION_SYSTEM_STRAIN: BL21(DE3); +SOURCE 7 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; +SOURCE 8 EXPRESSION_SYSTEM_PLASMID: PASK-IBA3PLUS +KEYWDS TRANSPORT PROTEIN, CSGG, CURLI TRANSPORTER, OUTER MEMBRANE +KEYWDS 2 LIPOPROTEIN, AMYLOID +EXPDTA X-RAY DIFFRACTION +AUTHOR P.GOYAL,P.V.KRASTEVA,N.V.GERVEN,F.GUBELLINI,I.V.D.BROECK, +AUTHOR 2 A.TROUPIOTIS-TSAILAKI,W.JONCKHEERE,G.PEHAU-ARNAUDET,J.S.PINKNER, +AUTHOR 3 M.R.CHAPMAN,S.J.HULTGREN,S.HOWORKA,R.FRONZES,H.REMAUT +REVDAT 2 17-DEC-14 4UV3 1 JRNL +REVDAT 1 24-SEP-14 4UV3 0 +JRNL AUTH P.GOYAL,P.V.KRASTEVA,N.VAN GERVEN,F.GUBELLINI, +JRNL AUTH 2 I.VAN DEN BROECK,A.TROUPIOTIS-TSAILAKI,W.JONCKHEERE, +JRNL AUTH 3 G.PEHAU-ARNAUDET,J.S.PINKNER,M.R.CHAPMAN,S.J.HULTGREN, +JRNL AUTH 4 S.HOWORKA,R.FRONZES,H.REMAUT +JRNL TITL STRUCTURAL AND MECHANISTIC INSIGHTS INTO THE BACTERIAL +JRNL TITL 2 AMYLOID SECRETION CHANNEL CSGG. +JRNL REF NATURE V. 516 250 2014 +JRNL REFN ISSN 0028-0836 +JRNL PMID 25219853 +JRNL DOI 10.1038/NATURE13768 +REMARK 2 +REMARK 2 RESOLUTION. 3.59 ANGSTROMS. +REMARK 3 +REMARK 3 REFINEMENT. +REMARK 3 PROGRAM : REFMAC 5.7.0029 +REMARK 3 AUTHORS : MURSHUDOV,SKUBAK,LEBEDEV,PANNU, +REMARK 3 STEINER,NICHOLLS,WINN,LONG,VAGIN +REMARK 3 +REMARK 3 REFINEMENT TARGET : MAXIMUM LIKELIHOOD +REMARK 3 +REMARK 3 DATA USED IN REFINEMENT. +REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 3.59 +REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 30.00 +REMARK 3 DATA CUTOFF (SIGMA(F)) : NONE +REMARK 3 COMPLETENESS FOR RANGE (%) : 91.50 +REMARK 3 NUMBER OF REFLECTIONS : 97020 +REMARK 3 +REMARK 3 FIT TO DATA USED IN REFINEMENT. +REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT +REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM +REMARK 3 R VALUE (WORKING + TEST SET) : 0.29921 +REMARK 3 R VALUE (WORKING SET) : 0.29661 +REMARK 3 FREE R VALUE : 0.34903 +REMARK 3 FREE R VALUE TEST SET SIZE (%) : 5.0 +REMARK 3 FREE R VALUE TEST SET COUNT : 5110 +REMARK 3 +REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. +REMARK 3 TOTAL NUMBER OF BINS USED : 20 +REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 3.587 +REMARK 3 BIN RESOLUTION RANGE LOW (A) : 3.680 +REMARK 3 REFLECTION IN BIN (WORKING SET) : 1429 +REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 18.18 +REMARK 3 BIN R VALUE (WORKING SET) : 0.334 +REMARK 3 BIN FREE R VALUE SET COUNT : 75 +REMARK 3 BIN FREE R VALUE : 0.403 +REMARK 3 +REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. +REMARK 3 PROTEIN ATOMS : 34255 +REMARK 3 NUCLEIC ACID ATOMS : 0 +REMARK 3 HETEROGEN ATOMS : 0 +REMARK 3 SOLVENT ATOMS : 0 +REMARK 3 +REMARK 3 B VALUES. +REMARK 3 FROM WILSON PLOT (A**2) : NULL +REMARK 3 MEAN B VALUE (OVERALL, A**2) : 115.072 +REMARK 3 OVERALL ANISOTROPIC B VALUE. +REMARK 3 B11 (A**2) : 2.18 +REMARK 3 B22 (A**2) : -3.72 +REMARK 3 B33 (A**2) : 1.56 +REMARK 3 B12 (A**2) : 0.00 +REMARK 3 B13 (A**2) : -0.41 +REMARK 3 B23 (A**2) : 0.00 +REMARK 3 +REMARK 3 ESTIMATED OVERALL COORDINATE ERROR. +REMARK 3 ESU BASED ON R VALUE (A): NULL +REMARK 3 ESU BASED ON FREE R VALUE (A): 0.780 +REMARK 3 ESU BASED ON MAXIMUM LIKELIHOOD (A): 0.619 +REMARK 3 ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 41.297 +REMARK 3 +REMARK 3 CORRELATION COEFFICIENTS. +REMARK 3 CORRELATION COEFFICIENT FO-FC : 0.813 +REMARK 3 CORRELATION COEFFICIENT FO-FC FREE : 0.773 +REMARK 3 +REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES COUNT RMS WEIGHT +REMARK 3 BOND LENGTHS REFINED ATOMS (A): 34795 ; 0.011 ; 0.019 +REMARK 3 BOND LENGTHS OTHERS (A): 33905 ; 0.008 ; 0.020 +REMARK 3 BOND ANGLES REFINED ATOMS (DEGREES): 47212 ; 1.364 ; 1.967 +REMARK 3 BOND ANGLES OTHERS (DEGREES): 77774 ; 1.300 ; 3.000 +REMARK 3 TORSION ANGLES, PERIOD 1 (DEGREES): 4397 ; 7.916 ; 5.000 +REMARK 3 TORSION ANGLES, PERIOD 2 (DEGREES): 1517 ;42.665 ;24.832 +REMARK 3 TORSION ANGLES, PERIOD 3 (DEGREES): 5991 ;21.375 ;15.000 +REMARK 3 TORSION ANGLES, PERIOD 4 (DEGREES): 221 ;17.873 ;15.000 +REMARK 3 CHIRAL-CENTER RESTRAINTS (A**3): 5513 ; 0.070 ; 0.200 +REMARK 3 GENERAL PLANES REFINED ATOMS (A): 39624 ; 0.014 ; 0.021 +REMARK 3 GENERAL PLANES OTHERS (A): 7693 ; 0.013 ; 0.020 +REMARK 3 NON-BONDED CONTACTS REFINED ATOMS (A): NULL ; NULL ; NULL +REMARK 3 NON-BONDED CONTACTS OTHERS (A): NULL ; NULL ; NULL +REMARK 3 NON-BONDED TORSION REFINED ATOMS (A): NULL ; NULL ; NULL +REMARK 3 NON-BONDED TORSION OTHERS (A): NULL ; NULL ; NULL +REMARK 3 H-BOND (X...Y) REFINED ATOMS (A): NULL ; NULL ; NULL +REMARK 3 H-BOND (X...Y) OTHERS (A): NULL ; NULL ; NULL +REMARK 3 POTENTIAL METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL +REMARK 3 POTENTIAL METAL-ION OTHERS (A): NULL ; NULL ; NULL +REMARK 3 SYMMETRY VDW REFINED ATOMS (A): NULL ; NULL ; NULL +REMARK 3 SYMMETRY VDW OTHERS (A): NULL ; NULL ; NULL +REMARK 3 SYMMETRY H-BOND REFINED ATOMS (A): NULL ; NULL ; NULL +REMARK 3 SYMMETRY H-BOND OTHERS (A): NULL ; NULL ; NULL +REMARK 3 SYMMETRY METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL +REMARK 3 SYMMETRY METAL-ION OTHERS (A): NULL ; NULL ; NULL +REMARK 3 +REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT +REMARK 3 MAIN-CHAIN BOND REFINED ATOMS (A**2): NULL ; NULL ; NULL +REMARK 3 MAIN-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL +REMARK 3 MAIN-CHAIN ANGLE REFINED ATOMS (A**2): NULL ; NULL ; NULL +REMARK 3 MAIN-CHAIN ANGLE OTHER ATOMS (A**2): NULL ; NULL ; NULL +REMARK 3 SIDE-CHAIN BOND REFINED ATOMS (A**2): NULL ; NULL ; NULL +REMARK 3 SIDE-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL +REMARK 3 SIDE-CHAIN ANGLE REFINED ATOMS (A**2): NULL ; NULL ; NULL +REMARK 3 SIDE-CHAIN ANGLE OTHER ATOMS (A**2): NULL ; NULL ; NULL +REMARK 3 LONG RANGE B REFINED ATOMS (A**2): NULL ; NULL ; NULL +REMARK 3 LONG RANGE B OTHER ATOMS (A**2): NULL ; NULL ; NULL +REMARK 3 +REMARK 3 ANISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT +REMARK 3 RIGID-BOND RESTRAINTS (A**2): NULL ; NULL ; NULL +REMARK 3 SPHERICITY; FREE ATOMS (A**2): NULL ; NULL ; NULL +REMARK 3 SPHERICITY; BONDED ATOMS (A**2): NULL ; NULL ; NULL +REMARK 3 +REMARK 3 NCS RESTRAINTS STATISTICS +REMARK 3 NCS TYPE: LOCAL +REMARK 3 NUMBER OF DIFFERENT NCS PAIRS : 153 +REMARK 3 GROUP CHAIN1 RANGE CHAIN2 RANGE COUNT RMS WEIGHT +REMARK 3 1 A 2 257 B 2 257 14054 0.07 0.05 +REMARK 3 2 A 2 257 C 2 257 14007 0.07 0.05 +REMARK 3 3 A 2 257 D 2 257 13844 0.08 0.05 +REMARK 3 4 A 2 257 E 2 257 13795 0.08 0.05 +REMARK 3 5 A 2 257 F 2 257 13886 0.07 0.05 +REMARK 3 6 A 2 257 G 2 257 13831 0.08 0.05 +REMARK 3 7 A 2 257 H 2 257 14063 0.07 0.05 +REMARK 3 8 A 2 257 I 2 257 13947 0.07 0.05 +REMARK 3 9 A 2 257 J 2 257 14013 0.08 0.05 +REMARK 3 10 A 2 257 K 2 257 13954 0.07 0.05 +REMARK 3 11 A 2 257 L 2 257 14151 0.06 0.05 +REMARK 3 12 A 2 257 M 2 257 13857 0.08 0.05 +REMARK 3 13 A 2 257 N 2 257 13997 0.08 0.05 +REMARK 3 14 A 2 257 O 2 257 13817 0.08 0.05 +REMARK 3 15 A 2 257 P 2 257 13844 0.08 0.05 +REMARK 3 16 A 2 257 Q 2 257 13849 0.08 0.05 +REMARK 3 17 A 2 257 R 2 257 13843 0.09 0.05 +REMARK 3 18 B 2 257 C 2 257 14086 0.06 0.05 +REMARK 3 19 B 2 257 D 2 257 14006 0.08 0.05 +REMARK 3 20 B 2 257 E 2 257 13875 0.08 0.05 +REMARK 3 21 B 2 257 F 2 257 13994 0.07 0.05 +REMARK 3 22 B 2 257 G 2 257 13845 0.08 0.05 +REMARK 3 23 B 2 257 H 2 257 14047 0.07 0.05 +REMARK 3 24 B 2 257 I 2 257 14135 0.07 0.05 +REMARK 3 25 B 2 257 J 2 257 14092 0.07 0.05 +REMARK 3 26 B 2 257 K 2 257 14040 0.07 0.05 +REMARK 3 27 B 2 257 L 2 257 14036 0.07 0.05 +REMARK 3 28 B 2 257 M 2 257 13980 0.07 0.05 +REMARK 3 29 B 2 257 N 2 257 14028 0.07 0.05 +REMARK 3 30 B 2 257 O 2 257 13966 0.07 0.05 +REMARK 3 31 B 2 257 P 2 257 13990 0.08 0.05 +REMARK 3 32 B 2 257 Q 2 257 13982 0.07 0.05 +REMARK 3 33 B 2 257 R 2 257 13879 0.09 0.05 +REMARK 3 34 C 2 257 D 2 257 14026 0.07 0.05 +REMARK 3 35 C 2 257 E 2 257 13979 0.08 0.05 +REMARK 3 36 C 2 257 F 2 257 14085 0.06 0.05 +REMARK 3 37 C 2 257 G 2 257 14041 0.07 0.05 +REMARK 3 38 C 2 257 H 2 257 14152 0.06 0.05 +REMARK 3 39 C 2 257 I 2 257 14157 0.07 0.05 +REMARK 3 40 C 2 257 J 2 257 14138 0.06 0.05 +REMARK 3 41 C 2 257 K 2 257 14157 0.06 0.05 +REMARK 3 42 C 2 257 L 2 257 14096 0.07 0.05 +REMARK 3 43 C 2 257 M 2 257 14070 0.07 0.05 +REMARK 3 44 C 2 257 N 2 257 14224 0.06 0.05 +REMARK 3 45 C 2 257 O 2 257 14031 0.07 0.05 +REMARK 3 46 C 2 257 P 2 257 14082 0.07 0.05 +REMARK 3 47 C 2 257 Q 2 257 14127 0.06 0.05 +REMARK 3 48 C 2 257 R 2 257 13982 0.08 0.05 +REMARK 3 49 D 2 257 E 2 257 13984 0.07 0.05 +REMARK 3 50 D 2 257 F 2 257 14083 0.06 0.05 +REMARK 3 51 D 2 257 G 2 257 14089 0.06 0.05 +REMARK 3 52 D 2 257 H 2 257 14150 0.06 0.05 +REMARK 3 53 D 2 257 I 2 257 14152 0.06 0.05 +REMARK 3 54 D 2 257 J 2 257 14146 0.06 0.05 +REMARK 3 55 D 2 257 K 2 257 14113 0.05 0.05 +REMARK 3 56 D 2 257 L 2 257 13996 0.07 0.05 +REMARK 3 57 D 2 257 M 2 257 14056 0.06 0.05 +REMARK 3 58 D 2 257 N 2 257 14079 0.06 0.05 +REMARK 3 59 D 2 257 O 2 257 14236 0.04 0.05 +REMARK 3 60 D 2 257 P 2 257 14060 0.06 0.05 +REMARK 3 61 D 2 257 Q 2 257 14090 0.06 0.05 +REMARK 3 62 D 2 257 R 2 257 13893 0.08 0.05 +REMARK 3 63 E 2 257 F 2 257 14015 0.07 0.05 +REMARK 3 64 E 2 257 G 2 257 13918 0.08 0.05 +REMARK 3 65 E 2 257 H 2 257 14029 0.07 0.05 +REMARK 3 66 E 2 257 I 2 257 14091 0.07 0.05 +REMARK 3 67 E 2 257 J 2 257 13966 0.08 0.05 +REMARK 3 68 E 2 257 K 2 257 14010 0.07 0.05 +REMARK 3 69 E 2 257 L 2 257 13962 0.08 0.05 +REMARK 3 70 E 2 257 M 2 257 13976 0.08 0.05 +REMARK 3 71 E 2 257 N 2 257 13974 0.08 0.05 +REMARK 3 72 E 2 257 O 2 257 13991 0.07 0.05 +REMARK 3 73 E 2 257 P 2 257 14014 0.08 0.05 +REMARK 3 74 E 2 257 Q 2 257 14012 0.08 0.05 +REMARK 3 75 E 2 257 R 2 257 13893 0.09 0.05 +REMARK 3 76 F 2 257 G 2 257 14018 0.07 0.05 +REMARK 3 77 F 2 257 H 2 257 14125 0.05 0.05 +REMARK 3 78 F 2 257 I 2 257 14187 0.05 0.05 +REMARK 3 79 F 2 257 J 2 257 14138 0.05 0.05 +REMARK 3 80 F 2 257 K 2 257 14148 0.05 0.05 +REMARK 3 81 F 2 257 L 2 257 14119 0.06 0.05 +REMARK 3 82 F 2 257 M 2 257 14110 0.06 0.05 +REMARK 3 83 F 2 257 N 2 257 14137 0.06 0.05 +REMARK 3 84 F 2 257 O 2 257 14100 0.06 0.05 +REMARK 3 85 F 2 257 P 2 257 14130 0.06 0.05 +REMARK 3 86 F 2 257 Q 2 257 14256 0.05 0.05 +REMARK 3 87 F 2 257 R 2 257 13980 0.07 0.05 +REMARK 3 88 G 2 257 H 2 257 14123 0.06 0.05 +REMARK 3 89 G 2 257 I 2 257 14097 0.06 0.05 +REMARK 3 90 G 2 257 J 2 257 14111 0.06 0.05 +REMARK 3 91 G 2 257 K 2 257 14134 0.06 0.05 +REMARK 3 92 G 2 257 L 2 257 13951 0.07 0.05 +REMARK 3 93 G 2 257 M 2 257 13960 0.07 0.05 +REMARK 3 94 G 2 257 N 2 257 14068 0.07 0.05 +REMARK 3 95 G 2 257 O 2 257 14070 0.07 0.05 +REMARK 3 96 G 2 257 P 2 257 14026 0.07 0.05 +REMARK 3 97 G 2 257 Q 2 257 14026 0.07 0.05 +REMARK 3 98 G 2 257 R 2 257 14072 0.07 0.05 +REMARK 3 99 H 2 257 I 2 257 14223 0.06 0.05 +REMARK 3 100 H 2 257 J 2 257 14384 0.05 0.05 +REMARK 3 101 H 2 257 K 2 257 14322 0.05 0.05 +REMARK 3 102 H 2 257 L 2 257 14077 0.06 0.05 +REMARK 3 103 H 2 257 M 2 257 14095 0.06 0.05 +REMARK 3 104 H 2 257 N 2 257 14233 0.06 0.05 +REMARK 3 105 H 2 257 O 2 257 14090 0.06 0.05 +REMARK 3 106 H 2 257 P 2 257 14099 0.07 0.05 +REMARK 3 107 H 2 257 Q 2 257 14125 0.06 0.05 +REMARK 3 108 H 2 257 R 2 257 14070 0.07 0.05 +REMARK 3 109 I 2 257 J 2 257 14261 0.05 0.05 +REMARK 3 110 I 2 257 K 2 257 14313 0.05 0.05 +REMARK 3 111 I 2 257 L 2 257 14106 0.07 0.05 +REMARK 3 112 I 2 257 M 2 257 14145 0.06 0.05 +REMARK 3 113 I 2 257 N 2 257 14170 0.06 0.05 +REMARK 3 114 I 2 257 O 2 257 14123 0.06 0.05 +REMARK 3 115 I 2 257 P 2 257 14171 0.06 0.05 +REMARK 3 116 I 2 257 Q 2 257 14206 0.06 0.05 +REMARK 3 117 I 2 257 R 2 257 14079 0.07 0.05 +REMARK 3 118 J 2 257 K 2 257 14399 0.03 0.05 +REMARK 3 119 J 2 257 L 2 257 14049 0.07 0.05 +REMARK 3 120 J 2 257 M 2 257 14098 0.06 0.05 +REMARK 3 121 J 2 257 N 2 257 14205 0.06 0.05 +REMARK 3 122 J 2 257 O 2 257 14044 0.06 0.05 +REMARK 3 123 J 2 257 P 2 257 14098 0.06 0.05 +REMARK 3 124 J 2 257 Q 2 257 14149 0.05 0.05 +REMARK 3 125 J 2 257 R 2 257 14109 0.07 0.05 +REMARK 3 126 K 2 257 L 2 257 14082 0.06 0.05 +REMARK 3 127 K 2 257 M 2 257 14100 0.06 0.05 +REMARK 3 128 K 2 257 N 2 257 14240 0.06 0.05 +REMARK 3 129 K 2 257 O 2 257 14079 0.06 0.05 +REMARK 3 130 K 2 257 P 2 257 14100 0.06 0.05 +REMARK 3 131 K 2 257 Q 2 257 14154 0.06 0.05 +REMARK 3 132 K 2 257 R 2 257 14134 0.07 0.05 +REMARK 3 133 L 2 257 M 2 257 14102 0.07 0.05 +REMARK 3 134 L 2 257 N 2 257 14058 0.07 0.05 +REMARK 3 135 L 2 257 O 2 257 14060 0.06 0.05 +REMARK 3 136 L 2 257 P 2 257 14096 0.06 0.05 +REMARK 3 137 L 2 257 Q 2 257 14091 0.07 0.05 +REMARK 3 138 L 2 257 R 2 257 13900 0.08 0.05 +REMARK 3 139 M 2 257 N 2 257 14102 0.06 0.05 +REMARK 3 140 M 2 257 O 2 257 14197 0.05 0.05 +REMARK 3 141 M 2 257 P 2 257 14217 0.06 0.05 +REMARK 3 142 M 2 257 Q 2 257 14295 0.05 0.05 +REMARK 3 143 M 2 257 R 2 257 14055 0.07 0.05 +REMARK 3 144 N 2 257 O 2 257 14116 0.06 0.05 +REMARK 3 145 N 2 257 P 2 257 14071 0.07 0.05 +REMARK 3 146 N 2 257 Q 2 257 14145 0.06 0.05 +REMARK 3 147 N 2 257 R 2 257 14069 0.08 0.05 +REMARK 3 148 O 2 257 P 2 257 14245 0.05 0.05 +REMARK 3 149 O 2 257 Q 2 257 14253 0.05 0.05 +REMARK 3 150 O 2 257 R 2 257 14058 0.07 0.05 +REMARK 3 151 P 2 257 Q 2 257 14276 0.05 0.05 +REMARK 3 152 P 2 257 R 2 257 14050 0.08 0.05 +REMARK 3 153 Q 2 257 R 2 257 14139 0.07 0.05 +REMARK 3 +REMARK 3 TLS DETAILS +REMARK 3 NUMBER OF TLS GROUPS : NULL +REMARK 3 +REMARK 3 BULK SOLVENT MODELLING. +REMARK 3 METHOD USED : BABINET MODEL WITH MASK +REMARK 3 PARAMETERS FOR MASK CALCULATION +REMARK 3 VDW PROBE RADIUS : 1.20 +REMARK 3 ION PROBE RADIUS : 0.80 +REMARK 3 SHRINKAGE RADIUS : 0.80 +REMARK 3 +REMARK 3 OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE +REMARK 3 RIDING POSITIONS. U VALUES REFINED INDIVIDUALLY +REMARK 4 +REMARK 4 4UV3 COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 +REMARK 100 +REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 13-AUG-14. +REMARK 100 THE PDBE ID CODE IS EBI-61433. +REMARK 200 +REMARK 200 EXPERIMENTAL DETAILS +REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION +REMARK 200 DATE OF DATA COLLECTION : 31-OCT-11 +REMARK 200 TEMPERATURE (KELVIN) : 100 +REMARK 200 PH : 8.5 +REMARK 200 NUMBER OF CRYSTALS USED : 1 +REMARK 200 +REMARK 200 SYNCHROTRON (Y/N) : Y +REMARK 200 RADIATION SOURCE : DIAMOND +REMARK 200 BEAMLINE : I03 +REMARK 200 X-RAY GENERATOR MODEL : NULL +REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M +REMARK 200 WAVELENGTH OR RANGE (A) : 0.9763 +REMARK 200 MONOCHROMATOR : NULL +REMARK 200 OPTICS : NULL +REMARK 200 +REMARK 200 DETECTOR TYPE : PIXEL (PILATUS 6M) +REMARK 200 DETECTOR MANUFACTURER : DECTRIS +REMARK 200 INTENSITY-INTEGRATION SOFTWARE : XDS +REMARK 200 DATA SCALING SOFTWARE : XSCALE +REMARK 200 +REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 102130 +REMARK 200 RESOLUTION RANGE HIGH (A) : 3.60 +REMARK 200 RESOLUTION RANGE LOW (A) : 30.00 +REMARK 200 REJECTION CRITERIA (SIGMA(I)) : 2.0 +REMARK 200 +REMARK 200 OVERALL. +REMARK 200 COMPLETENESS FOR RANGE (%) : 91.6 +REMARK 200 DATA REDUNDANCY : 4.4 +REMARK 200 R MERGE (I) : 0.16 +REMARK 200 R SYM (I) : NULL +REMARK 200 FOR THE DATA SET : 6.80 +REMARK 200 +REMARK 200 IN THE HIGHEST RESOLUTION SHELL. +REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 3.60 +REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 3.68 +REMARK 200 COMPLETENESS FOR SHELL (%) : 27.3 +REMARK 200 DATA REDUNDANCY IN SHELL : 4.3 +REMARK 200 R MERGE FOR SHELL (I) : 0.91 +REMARK 200 R SYM FOR SHELL (I) : NULL +REMARK 200 FOR SHELL : 1.89 +REMARK 200 +REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH +REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT +REMARK 200 SOFTWARE USED: PHASER +REMARK 200 STARTING MODEL: PDB ENTRY 4UV2 +REMARK 200 +REMARK 200 REMARK: DATA WERE ANISOTROPICALLY SCALED TO 3.6, 3.7 AND 3.8 +REMARK 200 ANGSTROM ALONG RECIPROCAL DIRECTIONS A, B AND C. +REMARK 280 +REMARK 280 CRYSTAL +REMARK 280 SOLVENT CONTENT, VS (%): 73 +REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 4.52 +REMARK 280 +REMARK 280 CRYSTALLIZATION CONDITIONS: 100 MM TRIS-HCL PH 8.0, 8% PEG +REMARK 280 4000, 100 MM NACL AND 500 MM MGCL2 +REMARK 290 +REMARK 290 CRYSTALLOGRAPHIC SYMMETRY +REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: C 1 2 1 +REMARK 290 +REMARK 290 SYMOP SYMMETRY +REMARK 290 NNNMMM OPERATOR +REMARK 290 1555 X,Y,Z +REMARK 290 2555 -X,Y,-Z +REMARK 290 3555 X+1/2,Y+1/2,Z +REMARK 290 4555 -X+1/2,Y+1/2,-Z +REMARK 290 +REMARK 290 WHERE NNN -> OPERATOR NUMBER +REMARK 290 MMM -> TRANSLATION VECTOR +REMARK 290 +REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS +REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM +REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY +REMARK 290 RELATED MOLECULES. +REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 +REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 +REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 +REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 +REMARK 290 SMTRY2 2 0.000000 1.000000 0.000000 0.00000 +REMARK 290 SMTRY3 2 0.000000 0.000000 -1.000000 0.00000 +REMARK 290 SMTRY1 3 1.000000 0.000000 0.000000 80.96700 +REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 186.42350 +REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 0.00000 +REMARK 290 SMTRY1 4 -1.000000 0.000000 0.000000 80.96700 +REMARK 290 SMTRY2 4 0.000000 1.000000 0.000000 186.42350 +REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000 +REMARK 290 +REMARK 290 REMARK: NULL +REMARK 300 +REMARK 300 BIOMOLECULE: 1, 2 +REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM +REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN +REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON +REMARK 300 BURIED SURFACE AREA. +REMARK 350 +REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN +REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE +REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS +REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND +REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. +REMARK 350 +REMARK 350 BIOMOLECULE: 1 +REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: NONAMERIC +REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: NONAMERIC +REMARK 350 SOFTWARE USED: PISA +REMARK 350 TOTAL BURIED SURFACE AREA: 56740 ANGSTROM**2 +REMARK 350 SURFACE AREA OF THE COMPLEX: 87290 ANGSTROM**2 +REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -256.4 KCAL/MOL +REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, I, H, B, C, D, E, F, G +REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 +REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 +REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 +REMARK 350 +REMARK 350 BIOMOLECULE: 2 +REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: NONAMERIC +REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: NONAMERIC +REMARK 350 SOFTWARE USED: PISA +REMARK 350 TOTAL BURIED SURFACE AREA: 56870 ANGSTROM**2 +REMARK 350 SURFACE AREA OF THE COMPLEX: 86830 ANGSTROM**2 +REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -258.5 KCAL/MOL +REMARK 350 APPLY THE FOLLOWING TO CHAINS: J, K, P, Q, R, M, N, O, L +REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 +REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 +REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 +REMARK 465 +REMARK 465 MISSING RESIDUES +REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE +REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN +REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) +REMARK 465 +REMARK 465 M RES C SSSEQI +REMARK 465 CYS A 1 +REMARK 465 PHE A 144 +REMARK 465 PHE A 193 +REMARK 465 ILE A 194 +REMARK 465 ASP A 195 +REMARK 465 TYR A 196 +REMARK 465 GLN A 197 +REMARK 465 ARG A 198 +REMARK 465 LEU A 199 +REMARK 465 VAL A 258 +REMARK 465 PRO A 259 +REMARK 465 PRO A 260 +REMARK 465 GLU A 261 +REMARK 465 SER A 262 +REMARK 465 CYS B 1 +REMARK 465 PHE B 144 +REMARK 465 PHE B 193 +REMARK 465 ILE B 194 +REMARK 465 ASP B 195 +REMARK 465 TYR B 196 +REMARK 465 GLN B 197 +REMARK 465 ARG B 198 +REMARK 465 LEU B 199 +REMARK 465 VAL B 258 +REMARK 465 PRO B 259 +REMARK 465 PRO B 260 +REMARK 465 GLU B 261 +REMARK 465 SER B 262 +REMARK 465 CYS C 1 +REMARK 465 PHE C 144 +REMARK 465 ARG C 192 +REMARK 465 PHE C 193 +REMARK 465 ILE C 194 +REMARK 465 ASP C 195 +REMARK 465 TYR C 196 +REMARK 465 GLN C 197 +REMARK 465 ARG C 198 +REMARK 465 LEU C 199 +REMARK 465 VAL C 258 +REMARK 465 PRO C 259 +REMARK 465 PRO C 260 +REMARK 465 GLU C 261 +REMARK 465 SER C 262 +REMARK 465 CYS D 1 +REMARK 465 PHE D 144 +REMARK 465 PHE D 193 +REMARK 465 ILE D 194 +REMARK 465 ASP D 195 +REMARK 465 TYR D 196 +REMARK 465 GLN D 197 +REMARK 465 ARG D 198 +REMARK 465 LEU D 199 +REMARK 465 VAL D 258 +REMARK 465 PRO D 259 +REMARK 465 PRO D 260 +REMARK 465 GLU D 261 +REMARK 465 SER D 262 +REMARK 465 CYS E 1 +REMARK 465 PHE E 144 +REMARK 465 ARG E 192 +REMARK 465 PHE E 193 +REMARK 465 ILE E 194 +REMARK 465 ASP E 195 +REMARK 465 TYR E 196 +REMARK 465 GLN E 197 +REMARK 465 ARG E 198 +REMARK 465 LEU E 199 +REMARK 465 VAL E 258 +REMARK 465 PRO E 259 +REMARK 465 PRO E 260 +REMARK 465 GLU E 261 +REMARK 465 SER E 262 +REMARK 465 CYS F 1 +REMARK 465 PHE F 144 +REMARK 465 ARG F 192 +REMARK 465 PHE F 193 +REMARK 465 ILE F 194 +REMARK 465 ASP F 195 +REMARK 465 TYR F 196 +REMARK 465 GLN F 197 +REMARK 465 ARG F 198 +REMARK 465 LEU F 199 +REMARK 465 VAL F 258 +REMARK 465 PRO F 259 +REMARK 465 PRO F 260 +REMARK 465 GLU F 261 +REMARK 465 SER F 262 +REMARK 465 CYS G 1 +REMARK 465 PHE G 144 +REMARK 465 ARG G 192 +REMARK 465 PHE G 193 +REMARK 465 ILE G 194 +REMARK 465 ASP G 195 +REMARK 465 TYR G 196 +REMARK 465 GLN G 197 +REMARK 465 ARG G 198 +REMARK 465 LEU G 199 +REMARK 465 VAL G 258 +REMARK 465 PRO G 259 +REMARK 465 PRO G 260 +REMARK 465 GLU G 261 +REMARK 465 SER G 262 +REMARK 465 CYS H 1 +REMARK 465 PHE H 144 +REMARK 465 PHE H 193 +REMARK 465 ILE H 194 +REMARK 465 ASP H 195 +REMARK 465 TYR H 196 +REMARK 465 GLN H 197 +REMARK 465 ARG H 198 +REMARK 465 LEU H 199 +REMARK 465 VAL H 258 +REMARK 465 PRO H 259 +REMARK 465 PRO H 260 +REMARK 465 GLU H 261 +REMARK 465 SER H 262 +REMARK 465 CYS I 1 +REMARK 465 PHE I 144 +REMARK 465 ARG I 192 +REMARK 465 PHE I 193 +REMARK 465 ILE I 194 +REMARK 465 ASP I 195 +REMARK 465 TYR I 196 +REMARK 465 GLN I 197 +REMARK 465 ARG I 198 +REMARK 465 LEU I 199 +REMARK 465 VAL I 258 +REMARK 465 PRO I 259 +REMARK 465 PRO I 260 +REMARK 465 GLU I 261 +REMARK 465 SER I 262 +REMARK 465 CYS J 1 +REMARK 465 PHE J 144 +REMARK 465 PHE J 193 +REMARK 465 ILE J 194 +REMARK 465 ASP J 195 +REMARK 465 TYR J 196 +REMARK 465 GLN J 197 +REMARK 465 ARG J 198 +REMARK 465 LEU J 199 +REMARK 465 VAL J 258 +REMARK 465 PRO J 259 +REMARK 465 PRO J 260 +REMARK 465 GLU J 261 +REMARK 465 SER J 262 +REMARK 465 CYS K 1 +REMARK 465 PHE K 144 +REMARK 465 ARG K 192 +REMARK 465 PHE K 193 +REMARK 465 ILE K 194 +REMARK 465 ASP K 195 +REMARK 465 TYR K 196 +REMARK 465 GLN K 197 +REMARK 465 ARG K 198 +REMARK 465 LEU K 199 +REMARK 465 VAL K 258 +REMARK 465 PRO K 259 +REMARK 465 PRO K 260 +REMARK 465 GLU K 261 +REMARK 465 SER K 262 +REMARK 465 CYS L 1 +REMARK 465 PHE L 144 +REMARK 465 ARG L 192 +REMARK 465 PHE L 193 +REMARK 465 ILE L 194 +REMARK 465 ASP L 195 +REMARK 465 TYR L 196 +REMARK 465 GLN L 197 +REMARK 465 ARG L 198 +REMARK 465 LEU L 199 +REMARK 465 VAL L 258 +REMARK 465 PRO L 259 +REMARK 465 PRO L 260 +REMARK 465 GLU L 261 +REMARK 465 SER L 262 +REMARK 465 CYS M 1 +REMARK 465 PHE M 144 +REMARK 465 ARG M 192 +REMARK 465 PHE M 193 +REMARK 465 ILE M 194 +REMARK 465 ASP M 195 +REMARK 465 TYR M 196 +REMARK 465 GLN M 197 +REMARK 465 ARG M 198 +REMARK 465 LEU M 199 +REMARK 465 VAL M 258 +REMARK 465 PRO M 259 +REMARK 465 PRO M 260 +REMARK 465 GLU M 261 +REMARK 465 SER M 262 +REMARK 465 CYS N 1 +REMARK 465 PHE N 144 +REMARK 465 ARG N 192 +REMARK 465 PHE N 193 +REMARK 465 ILE N 194 +REMARK 465 ASP N 195 +REMARK 465 TYR N 196 +REMARK 465 GLN N 197 +REMARK 465 ARG N 198 +REMARK 465 LEU N 199 +REMARK 465 VAL N 258 +REMARK 465 PRO N 259 +REMARK 465 PRO N 260 +REMARK 465 GLU N 261 +REMARK 465 SER N 262 +REMARK 465 CYS O 1 +REMARK 465 PHE O 144 +REMARK 465 ARG O 192 +REMARK 465 PHE O 193 +REMARK 465 ILE O 194 +REMARK 465 ASP O 195 +REMARK 465 TYR O 196 +REMARK 465 GLN O 197 +REMARK 465 ARG O 198 +REMARK 465 LEU O 199 +REMARK 465 VAL O 258 +REMARK 465 PRO O 259 +REMARK 465 PRO O 260 +REMARK 465 GLU O 261 +REMARK 465 SER O 262 +REMARK 465 CYS P 1 +REMARK 465 PHE P 144 +REMARK 465 ARG P 192 +REMARK 465 PHE P 193 +REMARK 465 ILE P 194 +REMARK 465 ASP P 195 +REMARK 465 TYR P 196 +REMARK 465 GLN P 197 +REMARK 465 ARG P 198 +REMARK 465 LEU P 199 +REMARK 465 VAL P 258 +REMARK 465 PRO P 259 +REMARK 465 PRO P 260 +REMARK 465 GLU P 261 +REMARK 465 SER P 262 +REMARK 465 CYS Q 1 +REMARK 465 PHE Q 144 +REMARK 465 ARG Q 192 +REMARK 465 PHE Q 193 +REMARK 465 ILE Q 194 +REMARK 465 ASP Q 195 +REMARK 465 TYR Q 196 +REMARK 465 GLN Q 197 +REMARK 465 ARG Q 198 +REMARK 465 LEU Q 199 +REMARK 465 VAL Q 258 +REMARK 465 PRO Q 259 +REMARK 465 PRO Q 260 +REMARK 465 GLU Q 261 +REMARK 465 SER Q 262 +REMARK 465 CYS R 1 +REMARK 465 PHE R 144 +REMARK 465 ARG R 192 +REMARK 465 PHE R 193 +REMARK 465 ILE R 194 +REMARK 465 ASP R 195 +REMARK 465 TYR R 196 +REMARK 465 GLN R 197 +REMARK 465 ARG R 198 +REMARK 465 LEU R 199 +REMARK 465 VAL R 258 +REMARK 465 PRO R 259 +REMARK 465 PRO R 260 +REMARK 465 GLU R 261 +REMARK 465 SER R 262 +REMARK 500 +REMARK 500 GEOMETRY AND STEREOCHEMISTRY +REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT +REMARK 500 +REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT. +REMARK 500 +REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE +REMARK 500 OE2 GLU A 92 NE ARG I 83 2.14 +REMARK 500 N GLY B 145 O PHE B 191 2.18 +REMARK 500 NH2 ARG F 162 OE1 GLU G 82 2.03 +REMARK 500 NE ARG K 83 OE2 GLU L 92 2.18 +REMARK 500 OD2 ASP L 233 NH2 ARG L 254 2.03 +REMARK 500 +REMARK 500 REMARK: NULL +REMARK 500 +REMARK 500 GEOMETRY AND STEREOCHEMISTRY +REMARK 500 SUBTOPIC: CLOSE CONTACTS +REMARK 500 +REMARK 500 THE FOLLOWING ATOMS THAT ARE RELATED BY CRYSTALLOGRAPHIC +REMARK 500 SYMMETRY ARE IN CLOSE CONTACT. AN ATOM LOCATED WITHIN 0.15 +REMARK 500 ANGSTROMS OF A SYMMETRY RELATED ATOM IS ASSUMED TO BE ON A +REMARK 500 SPECIAL POSITION AND IS, THEREFORE, LISTED IN REMARK 375 +REMARK 500 INSTEAD OF REMARK 500. ATOMS WITH NON-BLANK ALTERNATE +REMARK 500 LOCATION INDICATORS ARE NOT INCLUDED IN THE CALCULATIONS. +REMARK 500 +REMARK 500 DISTANCE CUTOFF: +REMARK 500 2.2 ANGSTROMS FOR CONTACTS NOT INVOLVING HYDROGEN ATOMS +REMARK 500 1.6 ANGSTROMS FOR CONTACTS INVOLVING HYDROGEN ATOMS +REMARK 500 +REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI SSYMOP DISTANCE +REMARK 500 O ARG A 245 NE2 GLN A 246 2555 2.13 +REMARK 500 +REMARK 500 REMARK: NULL +REMARK 500 +REMARK 500 GEOMETRY AND STEREOCHEMISTRY +REMARK 500 SUBTOPIC: TORSION ANGLES +REMARK 500 +REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: +REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; +REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). +REMARK 500 +REMARK 500 STANDARD TABLE: +REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) +REMARK 500 +REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- +REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 +REMARK 500 +REMARK 500 M RES CSSEQI PSI PHI +REMARK 500 THR A 3 -6.26 -142.29 +REMARK 500 ALA A 10 156.72 85.66 +REMARK 500 PRO A 16 82.91 -63.74 +REMARK 500 ALA A 18 -119.53 -113.23 +REMARK 500 HIS A 26 37.37 -83.68 +REMARK 500 ASN A 40 133.34 -170.36 +REMARK 500 GLU A 44 10.86 -67.06 +REMARK 500 GLN A 62 40.60 -89.77 +REMARK 500 ILE A 128 42.29 -95.56 +REMARK 500 THR A 168 -38.27 -136.66 +REMARK 500 SER A 173 129.01 -172.19 +REMARK 500 THR B 3 -6.29 -141.82 +REMARK 500 ALA B 10 158.85 84.83 +REMARK 500 ALA B 18 -120.14 -112.51 +REMARK 500 HIS B 26 37.00 -84.34 +REMARK 500 ASN B 40 134.88 -170.89 +REMARK 500 GLN B 62 37.67 -88.20 +REMARK 500 ILE B 128 42.39 -97.16 +REMARK 500 THR B 168 -35.67 -139.98 +REMARK 500 SER B 173 133.31 -171.29 +REMARK 500 ALA C 10 158.67 84.13 +REMARK 500 PRO C 16 82.69 -67.32 +REMARK 500 ALA C 18 -118.84 -113.30 +REMARK 500 HIS C 26 36.55 -84.52 +REMARK 500 GLU C 44 16.62 -68.75 +REMARK 500 GLN C 62 35.25 -88.07 +REMARK 500 THR C 168 -34.62 -137.90 +REMARK 500 SER C 173 133.66 -171.16 +REMARK 500 ALA D 10 158.10 83.31 +REMARK 500 PRO D 16 81.10 -64.42 +REMARK 500 ALA D 18 -118.53 -113.33 +REMARK 500 HIS D 26 37.09 -84.88 +REMARK 500 GLU D 44 16.32 -67.52 +REMARK 500 GLN D 62 35.50 -91.90 +REMARK 500 THR D 168 -35.71 -137.35 +REMARK 500 SER D 173 134.37 -170.49 +REMARK 500 THR E 3 -3.58 -141.59 +REMARK 500 ALA E 10 157.08 83.47 +REMARK 500 PRO E 16 79.70 -59.21 +REMARK 500 ALA E 18 -116.56 -113.11 +REMARK 500 HIS E 26 36.92 -85.31 +REMARK 500 GLU E 44 15.23 -66.79 +REMARK 500 GLN E 62 33.72 -87.92 +REMARK 500 THR E 168 -35.42 -140.02 +REMARK 500 THR F 3 -1.48 -151.40 +REMARK 500 ALA F 10 157.10 83.02 +REMARK 500 PRO F 16 82.24 -63.52 +REMARK 500 ALA F 18 -117.74 -111.16 +REMARK 500 HIS F 26 33.44 -83.07 +REMARK 500 GLN F 62 34.10 -87.99 +REMARK 500 +REMARK 500 THIS ENTRY HAS 151 RAMACHANDRAN OUTLIERS. +REMARK 500 +REMARK 500 REMARK: NULL +REMARK 500 +REMARK 500 GEOMETRY AND STEREOCHEMISTRY +REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS +REMARK 500 +REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH +REMARK 500 CIS AND TRANS CONFORMATION. CIS BONDS, IF ANY, ARE LISTED +REMARK 500 ON CISPEP RECORDS. TRANS IS DEFINED AS 180 +/- 30 AND +REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES. +REMARK 500 MODEL OMEGA +REMARK 500 LEU P 14 MET P 15 -149.08 +REMARK 500 +REMARK 500 REMARK: NULL +REMARK 500 +REMARK 500 GEOMETRY AND STEREOCHEMISTRY +REMARK 500 SUBTOPIC: CHIRAL CENTERS +REMARK 500 +REMARK 500 UNEXPECTED CONFIGURATION OF THE FOLLOWING CHIRAL +REMARK 500 CENTER(S) USING IMPROPER CA--C--CB--N CHIRALITY +REMARK 500 FOR AMINO ACIDS AND C1'--O4'--N1(N9)--C2' FOR +REMARK 500 NUCLEIC ACIDS OR EQUIVALENT ANGLE +REMARK 500 M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN +REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE +REMARK 500 +REMARK 500 STANDARD TABLE: +REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,6X,F5.1,6X,A1,10X,A1,3X,A16) +REMARK 500 +REMARK 500 M RES CSSEQI IMPROPER EXPECTED FOUND DETAILS +REMARK 500 ILE G 107 25.0 L L OUTSIDE RANGE +REMARK 500 +REMARK 500 REMARK: NULL +REMARK 700 +REMARK 700 SHEET +REMARK 700 THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN +REMARK 700 ORDER TO REPRESENT THIS FEATURE IN THE SHEET RECORDS BELOW, +REMARK 700 TWO SHEETS ARE DEFINED. +REMARK 900 +REMARK 900 RELATED ENTRIES +REMARK 900 RELATED ID: 4UV2 RELATED DB: PDB +REMARK 900 STRUCTURE OF THE CURLI TRANSPORT LIPOPROTEIN CSGG IN A +REMARK 900 NON-LIPIDATED, PRE-PORE CONFORMATION +REMARK 999 +REMARK 999 SEQUENCE +REMARK 999 MATURE CSGG, MEMBRANE FORM +DBREF 4UV3 A 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 B 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 C 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 D 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 E 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 F 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 G 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 H 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 I 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 J 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 K 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 L 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 M 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 N 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 O 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 P 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 Q 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +DBREF 4UV3 R 1 262 UNP P0AEA2 CSGG_ECOLI 16 277 +SEQRES 1 A 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 A 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 A 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 A 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 A 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 A 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 A 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 A 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 A 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 A 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 A 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 A 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 A 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 A 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 A 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 A 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 A 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 A 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 A 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 A 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 A 262 GLU SER +SEQRES 1 B 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 B 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 B 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 B 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 B 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 B 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 B 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 B 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 B 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 B 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 B 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 B 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 B 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 B 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 B 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 B 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 B 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 B 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 B 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 B 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 B 262 GLU SER +SEQRES 1 C 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 C 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 C 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 C 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 C 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 C 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 C 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 C 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 C 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 C 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 C 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 C 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 C 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 C 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 C 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 C 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 C 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 C 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 C 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 C 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 C 262 GLU SER +SEQRES 1 D 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 D 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 D 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 D 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 D 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 D 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 D 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 D 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 D 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 D 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 D 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 D 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 D 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 D 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 D 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 D 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 D 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 D 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 D 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 D 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 D 262 GLU SER +SEQRES 1 E 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 E 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 E 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 E 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 E 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 E 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 E 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 E 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 E 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 E 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 E 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 E 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 E 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 E 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 E 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 E 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 E 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 E 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 E 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 E 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 E 262 GLU SER +SEQRES 1 F 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 F 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 F 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 F 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 F 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 F 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 F 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 F 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 F 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 F 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 F 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 F 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 F 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 F 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 F 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 F 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 F 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 F 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 F 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 F 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 F 262 GLU SER +SEQRES 1 G 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 G 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 G 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 G 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 G 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 G 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 G 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 G 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 G 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 G 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 G 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 G 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 G 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 G 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 G 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 G 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 G 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 G 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 G 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 G 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 G 262 GLU SER +SEQRES 1 H 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 H 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 H 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 H 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 H 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 H 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 H 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 H 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 H 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 H 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 H 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 H 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 H 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 H 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 H 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 H 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 H 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 H 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 H 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 H 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 H 262 GLU SER +SEQRES 1 I 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 I 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 I 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 I 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 I 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 I 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 I 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 I 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 I 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 I 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 I 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 I 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 I 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 I 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 I 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 I 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 I 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 I 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 I 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 I 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 I 262 GLU SER +SEQRES 1 J 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 J 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 J 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 J 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 J 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 J 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 J 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 J 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 J 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 J 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 J 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 J 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 J 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 J 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 J 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 J 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 J 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 J 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 J 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 J 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 J 262 GLU SER +SEQRES 1 K 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 K 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 K 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 K 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 K 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 K 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 K 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 K 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 K 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 K 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 K 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 K 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 K 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 K 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 K 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 K 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 K 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 K 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 K 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 K 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 K 262 GLU SER +SEQRES 1 L 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 L 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 L 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 L 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 L 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 L 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 L 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 L 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 L 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 L 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 L 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 L 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 L 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 L 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 L 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 L 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 L 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 L 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 L 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 L 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 L 262 GLU SER +SEQRES 1 M 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 M 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 M 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 M 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 M 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 M 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 M 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 M 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 M 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 M 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 M 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 M 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 M 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 M 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 M 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 M 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 M 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 M 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 M 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 M 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 M 262 GLU SER +SEQRES 1 N 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 N 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 N 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 N 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 N 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 N 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 N 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 N 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 N 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 N 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 N 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 N 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 N 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 N 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 N 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 N 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 N 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 N 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 N 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 N 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 N 262 GLU SER +SEQRES 1 O 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 O 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 O 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 O 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 O 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 O 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 O 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 O 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 O 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 O 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 O 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 O 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 O 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 O 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 O 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 O 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 O 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 O 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 O 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 O 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 O 262 GLU SER +SEQRES 1 P 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 P 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 P 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 P 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 P 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 P 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 P 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 P 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 P 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 P 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 P 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 P 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 P 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 P 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 P 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 P 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 P 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 P 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 P 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 P 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 P 262 GLU SER +SEQRES 1 Q 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 Q 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 Q 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 Q 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 Q 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 Q 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 Q 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 Q 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 Q 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 Q 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 Q 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 Q 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 Q 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 Q 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 Q 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 Q 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 Q 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 Q 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 Q 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 Q 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 Q 262 GLU SER +SEQRES 1 R 262 CYS LEU THR ALA PRO PRO LYS GLU ALA ALA ARG PRO THR +SEQRES 2 R 262 LEU MET PRO ARG ALA GLN SER TYR LYS ASP LEU THR HIS +SEQRES 3 R 262 LEU PRO ALA PRO THR GLY LYS ILE PHE VAL SER VAL TYR +SEQRES 4 R 262 ASN ILE GLN ASP GLU THR GLY GLN PHE LYS PRO TYR PRO +SEQRES 5 R 262 ALA SER ASN PHE SER THR ALA VAL PRO GLN SER ALA THR +SEQRES 6 R 262 ALA MET LEU VAL THR ALA LEU LYS ASP SER ARG TRP PHE +SEQRES 7 R 262 ILE PRO LEU GLU ARG GLN GLY LEU GLN ASN LEU LEU ASN +SEQRES 8 R 262 GLU ARG LYS ILE ILE ARG ALA ALA GLN GLU ASN GLY THR +SEQRES 9 R 262 VAL ALA ILE ASN ASN ARG ILE PRO LEU GLN SER LEU THR +SEQRES 10 R 262 ALA ALA ASN ILE MET VAL GLU GLY SER ILE ILE GLY TYR +SEQRES 11 R 262 GLU SER ASN VAL LYS SER GLY GLY VAL GLY ALA ARG TYR +SEQRES 12 R 262 PHE GLY ILE GLY ALA ASP THR GLN TYR GLN LEU ASP GLN +SEQRES 13 R 262 ILE ALA VAL ASN LEU ARG VAL VAL ASN VAL SER THR GLY +SEQRES 14 R 262 GLU ILE LEU SER SER VAL ASN THR SER LYS THR ILE LEU +SEQRES 15 R 262 SER TYR GLU VAL GLN ALA GLY VAL PHE ARG PHE ILE ASP +SEQRES 16 R 262 TYR GLN ARG LEU LEU GLU GLY GLU VAL GLY TYR THR SER +SEQRES 17 R 262 ASN GLU PRO VAL MET LEU CYS LEU MET SER ALA ILE GLU +SEQRES 18 R 262 THR GLY VAL ILE PHE LEU ILE ASN ASP GLY ILE ASP ARG +SEQRES 19 R 262 GLY LEU TRP ASP LEU GLN ASN LYS ALA GLU ARG GLN ASN +SEQRES 20 R 262 ASP ILE LEU VAL LYS TYR ARG HIS MET SER VAL PRO PRO +SEQRES 21 R 262 GLU SER +HELIX 1 1 ALA A 18 HIS A 26 1 9 +HELIX 2 2 SER A 63 SER A 75 1 13 +HELIX 3 3 GLY A 85 GLU A 101 1 17 +HELIX 4 4 PRO A 211 ARG A 234 1 24 +HELIX 5 5 ASN A 241 GLN A 246 5 6 +HELIX 6 6 ASN A 247 SER A 257 1 11 +HELIX 7 7 ALA B 18 HIS B 26 1 9 +HELIX 8 8 SER B 63 SER B 75 1 13 +HELIX 9 9 GLY B 85 GLU B 101 1 17 +HELIX 10 10 PRO B 211 ARG B 234 1 24 +HELIX 11 11 ASN B 241 GLN B 246 5 6 +HELIX 12 12 ASN B 247 SER B 257 1 11 +HELIX 13 13 ALA C 18 HIS C 26 1 9 +HELIX 14 14 SER C 63 SER C 75 1 13 +HELIX 15 15 GLY C 85 GLU C 101 1 17 +HELIX 16 16 PRO C 211 ARG C 234 1 24 +HELIX 17 17 ASN C 241 GLN C 246 5 6 +HELIX 18 18 ASN C 247 SER C 257 1 11 +HELIX 19 19 ALA D 18 HIS D 26 1 9 +HELIX 20 20 SER D 63 SER D 75 1 13 +HELIX 21 21 GLY D 85 GLU D 101 1 17 +HELIX 22 22 PRO D 211 ARG D 234 1 24 +HELIX 23 23 ASN D 241 GLN D 246 5 6 +HELIX 24 24 ASN D 247 SER D 257 1 11 +HELIX 25 25 ALA E 18 HIS E 26 1 9 +HELIX 26 26 SER E 63 SER E 75 1 13 +HELIX 27 27 GLY E 85 GLU E 101 1 17 +HELIX 28 28 PRO E 211 ARG E 234 1 24 +HELIX 29 29 ASN E 241 GLN E 246 5 6 +HELIX 30 30 ASN E 247 SER E 257 1 11 +HELIX 31 31 ALA F 18 HIS F 26 1 9 +HELIX 32 32 SER F 63 SER F 75 1 13 +HELIX 33 33 GLY F 85 GLU F 101 1 17 +HELIX 34 34 PRO F 211 ARG F 234 1 24 +HELIX 35 35 ASN F 241 GLN F 246 5 6 +HELIX 36 36 ASN F 247 SER F 257 1 11 +HELIX 37 37 ALA G 18 HIS G 26 1 9 +HELIX 38 38 SER G 63 SER G 75 1 13 +HELIX 39 39 GLY G 85 GLU G 101 1 17 +HELIX 40 40 PRO G 211 GLY G 235 1 25 +HELIX 41 41 ASN G 241 GLN G 246 5 6 +HELIX 42 42 ASN G 247 SER G 257 1 11 +HELIX 43 43 ALA H 18 HIS H 26 1 9 +HELIX 44 44 SER H 63 SER H 75 1 13 +HELIX 45 45 GLY H 85 GLU H 101 1 17 +HELIX 46 46 PRO H 211 ARG H 234 1 24 +HELIX 47 47 ASN H 241 GLN H 246 5 6 +HELIX 48 48 ASN H 247 SER H 257 1 11 +HELIX 49 49 ALA I 18 HIS I 26 1 9 +HELIX 50 50 SER I 63 SER I 75 1 13 +HELIX 51 51 GLY I 85 GLU I 101 1 17 +HELIX 52 52 PRO I 211 ARG I 234 1 24 +HELIX 53 53 ASN I 241 GLN I 246 5 6 +HELIX 54 54 ASN I 247 SER I 257 1 11 +HELIX 55 55 ALA J 18 HIS J 26 1 9 +HELIX 56 56 SER J 63 SER J 75 1 13 +HELIX 57 57 GLY J 85 GLU J 101 1 17 +HELIX 58 58 PRO J 211 ARG J 234 1 24 +HELIX 59 59 ASN J 241 GLN J 246 5 6 +HELIX 60 60 ASN J 247 SER J 257 1 11 +HELIX 61 61 ALA K 18 HIS K 26 1 9 +HELIX 62 62 SER K 63 SER K 75 1 13 +HELIX 63 63 GLY K 85 GLU K 101 1 17 +HELIX 64 64 PRO K 211 ARG K 234 1 24 +HELIX 65 65 ASN K 241 GLN K 246 5 6 +HELIX 66 66 ASN K 247 SER K 257 1 11 +HELIX 67 67 ALA L 18 HIS L 26 1 9 +HELIX 68 68 SER L 63 SER L 75 1 13 +HELIX 69 69 GLY L 85 GLU L 101 1 17 +HELIX 70 70 PRO L 211 ARG L 234 1 24 +HELIX 71 71 ASN L 241 GLN L 246 5 6 +HELIX 72 72 ASN L 247 SER L 257 1 11 +HELIX 73 73 ALA M 18 HIS M 26 1 9 +HELIX 74 74 SER M 63 SER M 75 1 13 +HELIX 75 75 GLY M 85 GLU M 101 1 17 +HELIX 76 76 PRO M 211 ARG M 234 1 24 +HELIX 77 77 ASN M 241 GLN M 246 5 6 +HELIX 78 78 ASN M 247 SER M 257 1 11 +HELIX 79 79 ALA N 18 HIS N 26 1 9 +HELIX 80 80 SER N 63 SER N 75 1 13 +HELIX 81 81 GLY N 85 GLU N 101 1 17 +HELIX 82 82 PRO N 211 ARG N 234 1 24 +HELIX 83 83 ASN N 241 GLN N 246 5 6 +HELIX 84 84 ASN N 247 SER N 257 1 11 +HELIX 85 85 ALA O 18 HIS O 26 1 9 +HELIX 86 86 SER O 63 SER O 75 1 13 +HELIX 87 87 GLY O 85 GLU O 101 1 17 +HELIX 88 88 PRO O 211 ARG O 234 1 24 +HELIX 89 89 ASN O 241 GLN O 246 5 6 +HELIX 90 90 ASN O 247 SER O 257 1 11 +HELIX 91 91 ALA P 18 HIS P 26 1 9 +HELIX 92 92 SER P 63 SER P 75 1 13 +HELIX 93 93 GLY P 85 GLU P 101 1 17 +HELIX 94 94 PRO P 211 ARG P 234 1 24 +HELIX 95 95 ASN P 241 GLN P 246 5 6 +HELIX 96 96 ASN P 247 SER P 257 1 11 +HELIX 97 97 ALA Q 18 HIS Q 26 1 9 +HELIX 98 98 SER Q 63 SER Q 75 1 13 +HELIX 99 99 GLY Q 85 GLU Q 101 1 17 +HELIX 100 100 PRO Q 211 ARG Q 234 1 24 +HELIX 101 101 ASN Q 241 GLN Q 246 5 6 +HELIX 102 102 ASN Q 247 SER Q 257 1 11 +HELIX 103 103 ALA R 18 HIS R 26 1 9 +HELIX 104 104 SER R 63 SER R 75 1 13 +HELIX 105 105 GLY R 85 GLU R 101 1 17 +HELIX 106 106 PRO R 211 GLY R 235 1 25 +HELIX 107 107 ASN R 241 GLN R 246 5 6 +HELIX 108 108 ASN R 247 SER R 257 1 11 +SHEET 1 AA 4 THR A 13 LEU A 14 0 +SHEET 2 AA 4 ILE I 171 VAL I 190 1 O SER I 178 N THR A 13 +SHEET 3 AA 4 ILE I 146 ASN I 165 -1 O GLY I 147 N GLY I 189 +SHEET 4 AA 4 ILE I 121 ARG I 142 -1 O MET I 122 N VAL I 164 +SHEET 1 AB 2 THR A 13 LEU A 14 0 +SHEET 2 AB 2 ILE I 171 VAL I 190 1 O SER I 178 N THR A 13 +SHEET 1 JA 4 THR J 13 LEU J 14 0 +SHEET 2 JA 4 ILE R 171 VAL R 190 1 O SER R 178 N THR J 13 +SHEET 3 JA 4 ILE R 146 ASN R 165 -1 O GLY R 147 N GLY R 189 +SHEET 4 JA 4 ILE R 121 ARG R 142 -1 O MET R 122 N VAL R 164 +SHEET 1 JB 2 THR J 13 LEU J 14 0 +SHEET 2 JB 2 ILE R 171 VAL R 190 1 O SER R 178 N THR J 13 +CISPEP 1 TYR A 51 PRO A 52 0 7.91 +CISPEP 2 TYR B 51 PRO B 52 0 8.44 +CISPEP 3 TYR C 51 PRO C 52 0 6.71 +CISPEP 4 TYR D 51 PRO D 52 0 9.36 +CISPEP 5 TYR E 51 PRO E 52 0 7.85 +CISPEP 6 TYR F 51 PRO F 52 0 6.58 +CISPEP 7 TYR G 51 PRO G 52 0 7.79 +CISPEP 8 TYR H 51 PRO H 52 0 12.62 +CISPEP 9 TYR I 51 PRO I 52 0 8.95 +CISPEP 10 TYR J 51 PRO J 52 0 12.45 +CISPEP 11 TYR K 51 PRO K 52 0 8.03 +CISPEP 12 TYR L 51 PRO L 52 0 8.29 +CISPEP 13 TYR M 51 PRO M 52 0 8.45 +CISPEP 14 TYR N 51 PRO N 52 0 8.04 +CISPEP 15 TYR O 51 PRO O 52 0 8.77 +CISPEP 16 TYR P 51 PRO P 52 0 8.47 +CISPEP 17 TYR Q 51 PRO Q 52 0 6.60 +CISPEP 18 TYR R 51 PRO R 52 0 7.97 +CRYST1 161.934 372.847 161.972 90.00 92.90 90.00 C 1 2 1 72 +ORIGX1 1.000000 0.000000 0.000000 0.00000 +ORIGX2 0.000000 1.000000 0.000000 0.00000 +ORIGX3 0.000000 0.000000 1.000000 0.00000 +SCALE1 0.006175 0.000000 0.000313 0.00000 +SCALE2 0.000000 0.002682 0.000000 0.00000 +SCALE3 0.000000 0.000000 0.006182 0.00000 +MTRIX1 1 0.762000 0.010000 0.648000 -17.50403 1 +MTRIX2 1 -0.012000 1.000000 -0.002000 0.41453 1 +MTRIX3 1 -0.648000 -0.006000 0.762000 34.08517 1 +MTRIX1 2 0.168000 0.008000 0.986000 -9.23430 1 +MTRIX2 2 -0.016000 1.000000 -0.006000 0.73640 1 +MTRIX3 2 -0.986000 -0.014000 0.168000 71.23841 1 +MTRIX1 3 -0.503000 0.000000 0.864000 20.88865 1 +MTRIX2 3 -0.022000 1.000000 -0.013000 1.24095 1 +MTRIX3 3 -0.864000 -0.025000 -0.503000 94.27494 1 +MTRIX1 4 -0.940000 -0.009000 0.342000 58.90655 1 +MTRIX2 4 -0.017000 1.000000 -0.020000 1.45010 1 +MTRIX3 4 -0.342000 -0.025000 -0.939000 92.72350 1 +MTRIX1 5 -0.938000 -0.015000 -0.345000 87.07927 1 +MTRIX2 5 -0.007000 1.000000 -0.025000 1.34548 1 +MTRIX3 5 0.345000 -0.021000 -0.938000 66.84988 1 +MTRIX1 6 -0.496000 -0.025000 -0.868000 91.79681 1 +MTRIX2 6 0.000000 1.000000 -0.029000 1.11549 1 +MTRIX3 6 0.868000 -0.014000 -0.496000 29.04159 1 +MTRIX1 7 0.180000 -0.024000 -0.983000 71.20045 1 +MTRIX2 7 0.001000 1.000000 -0.024000 0.79269 1 +MTRIX3 7 0.984000 0.004000 0.180000 -2.83411 1 +MTRIX1 8 0.769000 -0.013000 -0.639000 35.00981 1 +MTRIX2 8 0.005000 1.000000 -0.014000 0.23753 1 +MTRIX3 8 0.639000 0.007000 0.769000 -14.33744 1 +MTRIX1 9 -0.974000 -0.004000 -0.227000 83.29317 1 +MTRIX2 9 -0.002000 -1.000000 0.023000 -0.07177 1 +MTRIX3 9 -0.227000 0.023000 0.974000 9.79241 1 +ATOM 1 N LEU A 2 58.798 -55.137 9.066 1.00133.91 N +ATOM 2 CA LEU A 2 57.398 -55.272 9.581 1.00130.54 C +ATOM 3 C LEU A 2 57.356 -55.002 11.102 1.00126.78 C +ATOM 4 O LEU A 2 57.122 -55.909 11.930 1.00 81.16 O +ATOM 5 CB LEU A 2 56.813 -56.651 9.235 1.00129.67 C +ATOM 6 CG LEU A 2 56.671 -57.040 7.744 1.00135.10 C +ATOM 7 CD1 LEU A 2 56.096 -58.450 7.648 1.00137.37 C +ATOM 8 CD2 LEU A 2 55.832 -56.071 6.899 1.00128.75 C +ATOM 9 N THR A 3 57.711 -53.756 11.428 1.00137.44 N +ATOM 10 CA THR A 3 57.446 -53.120 12.716 1.00156.27 C +ATOM 11 C THR A 3 57.086 -51.618 12.543 1.00172.69 C +ATOM 12 O THR A 3 56.773 -50.925 13.522 1.00150.81 O +ATOM 13 CB THR A 3 58.663 -53.186 13.658 1.00150.05 C +ATOM 14 OG1 THR A 3 59.717 -52.342 13.149 1.00197.81 O +ATOM 15 CG2 THR A 3 59.143 -54.627 13.840 1.00116.36 C +ATOM 16 N ALA A 4 57.193 -51.104 11.318 1.00172.36 N +ATOM 17 CA ALA A 4 56.618 -49.795 10.976 1.00150.26 C +ATOM 18 C ALA A 4 55.082 -49.931 10.827 1.00132.67 C +ATOM 19 O ALA A 4 54.524 -50.995 11.103 1.00125.50 O +ATOM 20 CB ALA A 4 57.256 -49.246 9.704 1.00148.57 C +ATOM 21 N PRO A 5 54.373 -48.860 10.427 1.00112.96 N +ATOM 22 CA PRO A 5 52.942 -49.003 10.718 1.00112.60 C +ATOM 23 C PRO A 5 52.230 -49.757 9.627 1.00118.25 C +ATOM 24 O PRO A 5 52.826 -50.027 8.585 1.00141.63 O +ATOM 25 CB PRO A 5 52.448 -47.560 10.767 1.00115.75 C +ATOM 26 CG PRO A 5 53.415 -46.772 9.928 1.00109.65 C +ATOM 27 CD PRO A 5 54.698 -47.556 9.818 1.00 98.27 C +ATOM 28 N PRO A 6 50.978 -50.146 9.876 1.00136.67 N +ATOM 29 CA PRO A 6 50.110 -50.615 8.786 1.00166.30 C +ATOM 30 C PRO A 6 49.462 -49.480 7.973 1.00160.59 C +ATOM 31 O PRO A 6 49.262 -48.389 8.485 1.00122.73 O +ATOM 32 CB PRO A 6 49.040 -51.432 9.505 1.00142.58 C +ATOM 33 CG PRO A 6 49.086 -51.018 10.929 1.00130.38 C +ATOM 34 CD PRO A 6 50.393 -50.337 11.209 1.00116.44 C +ATOM 35 N LYS A 7 49.190 -49.733 6.695 1.00149.81 N +ATOM 36 CA LYS A 7 48.560 -48.729 5.825 1.00142.84 C +ATOM 37 C LYS A 7 47.061 -48.962 5.720 1.00114.99 C +ATOM 38 O LYS A 7 46.546 -50.000 6.160 1.00 64.03 O +ATOM 39 CB LYS A 7 49.184 -48.709 4.417 1.00156.91 C +ATOM 40 CG LYS A 7 50.590 -48.147 4.349 1.00151.81 C +ATOM 41 CD LYS A 7 51.666 -49.215 4.190 1.00137.38 C +ATOM 42 CE LYS A 7 52.997 -48.572 3.828 1.00122.26 C +ATOM 43 NZ LYS A 7 54.153 -49.370 4.323 1.00130.32 N +ATOM 44 N GLU A 8 46.369 -47.975 5.146 1.00109.03 N +ATOM 45 CA GLU A 8 44.911 -47.828 5.306 1.00105.93 C +ATOM 46 C GLU A 8 44.128 -48.923 4.616 1.00 90.77 C +ATOM 47 O GLU A 8 44.215 -49.100 3.417 1.00 84.71 O +ATOM 48 CB GLU A 8 44.413 -46.427 4.841 1.00109.86 C +ATOM 49 CG GLU A 8 44.210 -46.209 3.361 1.00121.39 C +ATOM 50 CD GLU A 8 43.553 -44.864 3.059 1.00129.92 C +ATOM 51 OE1 GLU A 8 42.460 -44.580 3.605 1.00143.56 O +ATOM 52 OE2 GLU A 8 44.081 -44.118 2.209 1.00121.24 O +ATOM 53 N ALA A 9 43.377 -49.670 5.415 1.00101.52 N +ATOM 54 CA ALA A 9 42.424 -50.644 4.920 1.00103.62 C +ATOM 55 C ALA A 9 41.028 -50.013 4.872 1.00 97.03 C +ATOM 56 O ALA A 9 40.446 -49.720 5.915 1.00 75.01 O +ATOM 57 CB ALA A 9 42.436 -51.873 5.823 1.00 96.07 C +ATOM 58 N ALA A 10 40.515 -49.817 3.650 1.00 89.99 N +ATOM 59 CA ALA A 10 39.259 -49.091 3.371 1.00 84.62 C +ATOM 60 C ALA A 10 39.519 -47.612 3.267 1.00 75.53 C +ATOM 61 O ALA A 10 40.513 -47.104 3.791 1.00 66.37 O +ATOM 62 CB ALA A 10 38.168 -49.395 4.401 1.00 87.96 C +ATOM 63 N ARG A 11 38.630 -46.921 2.572 1.00 96.51 N +ATOM 64 CA ARG A 11 38.873 -45.525 2.182 1.00150.64 C +ATOM 65 C ARG A 11 38.074 -44.543 3.052 1.00139.64 C +ATOM 66 O ARG A 11 37.003 -44.891 3.526 1.00158.38 O +ATOM 67 CB ARG A 11 38.472 -45.323 0.709 1.00190.90 C +ATOM 68 CG ARG A 11 36.979 -45.442 0.439 1.00205.27 C +ATOM 69 CD ARG A 11 36.695 -45.881 -0.994 1.00195.44 C +ATOM 70 NE ARG A 11 36.047 -47.188 -1.042 1.00190.72 N +ATOM 71 CZ ARG A 11 35.609 -47.759 -2.160 1.00180.65 C +ATOM 72 NH1 ARG A 11 35.777 -47.148 -3.323 1.00188.61 N +ATOM 73 NH2 ARG A 11 35.007 -48.944 -2.123 1.00169.43 N +ATOM 74 N PRO A 12 38.558 -43.290 3.210 1.00108.20 N +ATOM 75 CA PRO A 12 37.683 -42.267 3.758 1.00 91.67 C +ATOM 76 C PRO A 12 36.548 -41.968 2.797 1.00109.99 C +ATOM 77 O PRO A 12 36.773 -41.513 1.668 1.00118.93 O +ATOM 78 CB PRO A 12 38.590 -41.043 3.899 1.00 89.68 C +ATOM 79 CG PRO A 12 39.982 -41.546 3.727 1.00110.54 C +ATOM 80 CD PRO A 12 39.873 -42.742 2.847 1.00110.32 C +ATOM 81 N THR A 13 35.332 -42.296 3.220 1.00112.33 N +ATOM 82 CA THR A 13 34.130 -41.847 2.529 1.00105.27 C +ATOM 83 C THR A 13 33.552 -40.608 3.218 1.00 98.90 C +ATOM 84 O THR A 13 33.871 -40.353 4.377 1.00 92.80 O +ATOM 85 CB THR A 13 33.070 -42.948 2.543 1.00103.75 C +ATOM 86 OG1 THR A 13 32.002 -42.576 1.663 1.00134.18 O +ATOM 87 CG2 THR A 13 32.548 -43.233 3.991 1.00 82.49 C +ATOM 88 N LEU A 14 32.704 -39.841 2.535 1.00 82.49 N +ATOM 89 CA LEU A 14 31.968 -38.799 3.259 1.00 78.87 C +ATOM 90 C LEU A 14 30.826 -39.483 4.034 1.00 73.13 C +ATOM 91 O LEU A 14 30.543 -40.643 3.792 1.00 69.10 O +ATOM 92 CB LEU A 14 31.511 -37.645 2.369 1.00 69.12 C +ATOM 93 CG LEU A 14 30.734 -37.983 1.124 1.00 81.33 C +ATOM 94 CD1 LEU A 14 29.714 -36.889 0.833 1.00105.71 C +ATOM 95 CD2 LEU A 14 31.675 -38.111 -0.044 1.00 80.85 C +ATOM 96 N MET A 15 30.308 -38.852 5.079 1.00 74.12 N +ATOM 97 CA MET A 15 29.715 -39.604 6.185 1.00 86.14 C +ATOM 98 C MET A 15 28.412 -40.284 5.749 1.00 96.79 C +ATOM 99 O MET A 15 27.493 -39.611 5.284 1.00155.08 O +ATOM 100 CB MET A 15 29.487 -38.705 7.422 1.00 98.24 C +ATOM 101 CG MET A 15 29.489 -39.487 8.690 1.00120.85 C +ATOM 102 SD MET A 15 28.725 -38.568 10.139 1.00156.66 S +ATOM 103 CE MET A 15 27.303 -39.496 10.478 1.00161.32 C +ATOM 104 N PRO A 16 28.318 -41.622 5.929 1.00 79.96 N +ATOM 105 CA PRO A 16 27.212 -42.439 5.456 1.00 84.27 C +ATOM 106 C PRO A 16 25.853 -42.095 6.105 1.00 94.57 C +ATOM 107 O PRO A 16 25.363 -42.834 6.962 1.00109.08 O +ATOM 108 CB PRO A 16 27.653 -43.867 5.823 1.00 75.99 C +ATOM 109 CG PRO A 16 28.570 -43.700 6.964 1.00 62.85 C +ATOM 110 CD PRO A 16 29.299 -42.433 6.666 1.00 72.81 C +ATOM 111 N ARG A 17 25.197 -41.074 5.566 1.00 83.81 N +ATOM 112 CA ARG A 17 23.811 -40.777 5.898 1.00 84.48 C +ATOM 113 C ARG A 17 22.831 -41.524 4.987 1.00 89.42 C +ATOM 114 O ARG A 17 23.161 -41.824 3.844 1.00 99.62 O +ATOM 115 CB ARG A 17 23.579 -39.296 5.752 1.00 86.23 C +ATOM 116 CG ARG A 17 23.963 -38.502 6.994 1.00 94.47 C +ATOM 117 CD ARG A 17 24.121 -37.009 6.720 1.00 84.78 C +ATOM 118 NE ARG A 17 25.406 -36.715 6.094 1.00114.88 N +ATOM 119 CZ ARG A 17 25.739 -35.536 5.583 1.00122.52 C +ATOM 120 NH1 ARG A 17 24.878 -34.536 5.671 1.00113.37 N +ATOM 121 NH2 ARG A 17 26.936 -35.350 5.009 1.00125.33 N +ATOM 122 N ALA A 18 21.687 -41.941 5.530 1.00 90.24 N +ATOM 123 CA ALA A 18 20.759 -42.807 4.782 1.00113.56 C +ATOM 124 C ALA A 18 19.439 -42.108 4.454 1.00132.83 C +ATOM 125 O ALA A 18 19.444 -41.095 3.751 1.00178.34 O +ATOM 126 CB ALA A 18 20.509 -44.134 5.502 1.00119.82 C +ATOM 127 N GLN A 19 18.318 -42.648 4.941 1.00106.56 N +ATOM 128 CA GLN A 19 17.007 -42.309 4.380 1.00 89.89 C +ATOM 129 C GLN A 19 16.592 -40.873 4.703 1.00 85.09 C +ATOM 130 O GLN A 19 16.177 -40.104 3.825 1.00 69.80 O +ATOM 131 CB GLN A 19 15.949 -43.281 4.894 1.00 89.81 C +ATOM 132 CG GLN A 19 14.573 -43.116 4.254 1.00108.83 C +ATOM 133 CD GLN A 19 14.598 -43.197 2.735 1.00119.36 C +ATOM 134 OE1 GLN A 19 14.918 -44.241 2.161 1.00111.97 O +ATOM 135 NE2 GLN A 19 14.312 -42.075 2.077 1.00122.76 N +ATOM 136 N SER A 20 16.698 -40.539 5.986 1.00104.31 N +ATOM 137 CA SER A 20 16.479 -39.181 6.491 1.00 96.70 C +ATOM 138 C SER A 20 17.152 -38.119 5.620 1.00 72.43 C +ATOM 139 O SER A 20 16.496 -37.192 5.138 1.00 63.08 O +ATOM 140 CB SER A 20 17.011 -39.085 7.927 1.00 89.10 C +ATOM 141 OG SER A 20 16.484 -40.145 8.725 1.00 77.08 O +ATOM 142 N TYR A 21 18.430 -38.333 5.345 1.00 68.45 N +ATOM 143 CA TYR A 21 19.167 -37.503 4.403 1.00 85.55 C +ATOM 144 C TYR A 21 18.499 -37.366 3.017 1.00 95.87 C +ATOM 145 O TYR A 21 18.366 -36.246 2.481 1.00 61.26 O +ATOM 146 CB TYR A 21 20.588 -38.046 4.220 1.00 93.17 C +ATOM 147 CG TYR A 21 21.450 -37.172 3.329 1.00108.57 C +ATOM 148 CD1 TYR A 21 21.976 -35.977 3.802 1.00126.46 C +ATOM 149 CD2 TYR A 21 21.727 -37.527 2.014 1.00112.49 C +ATOM 150 CE1 TYR A 21 22.766 -35.171 3.003 1.00129.89 C +ATOM 151 CE2 TYR A 21 22.509 -36.716 1.199 1.00112.91 C +ATOM 152 CZ TYR A 21 23.029 -35.542 1.708 1.00123.43 C +ATOM 153 OH TYR A 21 23.874 -34.749 0.966 1.00203.56 O +ATOM 154 N LYS A 22 18.157 -38.512 2.407 1.00107.72 N +ATOM 155 CA LYS A 22 17.597 -38.548 1.046 1.00 98.71 C +ATOM 156 C LYS A 22 16.286 -37.780 0.958 1.00 99.74 C +ATOM 157 O LYS A 22 16.055 -37.031 0.002 1.00 88.58 O +ATOM 158 CB LYS A 22 17.368 -39.981 0.603 1.00 91.04 C +ATOM 159 CG LYS A 22 18.562 -40.597 -0.083 1.00123.06 C +ATOM 160 CD LYS A 22 18.605 -40.171 -1.561 1.00165.62 C +ATOM 161 CE LYS A 22 18.086 -41.305 -2.457 1.00198.92 C +ATOM 162 NZ LYS A 22 18.977 -42.496 -2.404 1.00213.03 N +ATOM 163 N ASP A 23 15.476 -37.909 2.006 1.00 93.22 N +ATOM 164 CA ASP A 23 14.267 -37.109 2.145 1.00 80.35 C +ATOM 165 C ASP A 23 14.598 -35.632 2.292 1.00 80.61 C +ATOM 166 O ASP A 23 13.964 -34.770 1.656 1.00102.01 O +ATOM 167 CB ASP A 23 13.455 -37.580 3.353 1.00 66.28 C +ATOM 168 CG ASP A 23 12.916 -38.969 3.165 1.00 66.35 C +ATOM 169 OD1 ASP A 23 12.425 -39.248 2.048 1.00 65.34 O +ATOM 170 OD2 ASP A 23 12.917 -39.749 4.140 1.00 57.47 O +ATOM 171 N LEU A 24 15.579 -35.344 3.144 1.00 67.72 N +ATOM 172 CA LEU A 24 15.911 -33.964 3.522 1.00 87.82 C +ATOM 173 C LEU A 24 16.468 -33.155 2.349 1.00 89.24 C +ATOM 174 O LEU A 24 16.185 -31.944 2.219 1.00 66.31 O +ATOM 175 CB LEU A 24 16.927 -33.975 4.661 1.00 85.84 C +ATOM 176 CG LEU A 24 17.407 -32.622 5.210 1.00 83.22 C +ATOM 177 CD1 LEU A 24 16.479 -32.097 6.295 1.00 72.58 C +ATOM 178 CD2 LEU A 24 18.820 -32.768 5.752 1.00104.09 C +ATOM 179 N THR A 25 17.201 -33.844 1.477 1.00 96.34 N +ATOM 180 CA THR A 25 17.815 -33.199 0.317 1.00110.91 C +ATOM 181 C THR A 25 16.820 -32.916 -0.795 1.00110.70 C +ATOM 182 O THR A 25 16.774 -31.789 -1.325 1.00114.43 O +ATOM 183 CB THR A 25 18.958 -34.053 -0.260 1.00110.18 C +ATOM 184 OG1 THR A 25 18.538 -35.413 -0.373 1.00 86.32 O +ATOM 185 CG2 THR A 25 20.175 -33.972 0.660 1.00125.58 C +ATOM 186 N HIS A 26 16.006 -33.923 -1.115 1.00109.50 N +ATOM 187 CA HIS A 26 15.014 -33.818 -2.180 1.00115.64 C +ATOM 188 C HIS A 26 13.713 -33.153 -1.687 1.00113.85 C +ATOM 189 O HIS A 26 12.629 -33.491 -2.131 1.00128.23 O +ATOM 190 CB HIS A 26 14.733 -35.204 -2.782 1.00107.33 C +ATOM 191 CG HIS A 26 15.927 -35.820 -3.448 1.00126.50 C +ATOM 192 ND1 HIS A 26 17.023 -36.257 -2.737 1.00147.22 N +ATOM 193 CD2 HIS A 26 16.229 -36.009 -4.758 1.00119.04 C +ATOM 194 CE1 HIS A 26 17.935 -36.717 -3.576 1.00154.32 C +ATOM 195 NE2 HIS A 26 17.484 -36.563 -4.809 1.00135.51 N +ATOM 196 N LEU A 27 13.831 -32.158 -0.814 1.00117.51 N +ATOM 197 CA LEU A 27 12.675 -31.370 -0.389 1.00104.46 C +ATOM 198 C LEU A 27 12.483 -30.202 -1.339 1.00 94.54 C +ATOM 199 O LEU A 27 13.446 -29.501 -1.666 1.00106.19 O +ATOM 200 CB LEU A 27 12.851 -30.851 1.047 1.00107.62 C +ATOM 201 CG LEU A 27 12.382 -31.803 2.149 1.00106.16 C +ATOM 202 CD1 LEU A 27 12.896 -31.360 3.509 1.00 97.91 C +ATOM 203 CD2 LEU A 27 10.869 -31.926 2.164 1.00102.14 C +ATOM 204 N PRO A 28 11.236 -29.971 -1.766 1.00 82.18 N +ATOM 205 CA PRO A 28 10.930 -28.847 -2.649 1.00 74.24 C +ATOM 206 C PRO A 28 11.317 -27.510 -2.061 1.00 72.59 C +ATOM 207 O PRO A 28 10.972 -27.209 -0.927 1.00 97.49 O +ATOM 208 CB PRO A 28 9.421 -28.922 -2.796 1.00 78.48 C +ATOM 209 CG PRO A 28 8.942 -29.638 -1.575 1.00 79.74 C +ATOM 210 CD PRO A 28 10.019 -30.623 -1.253 1.00 80.54 C +ATOM 211 N ALA A 29 12.042 -26.705 -2.817 1.00 79.54 N +ATOM 212 CA ALA A 29 12.699 -25.516 -2.251 1.00 86.43 C +ATOM 213 C ALA A 29 11.698 -24.390 -1.938 1.00 65.83 C +ATOM 214 O ALA A 29 10.678 -24.247 -2.609 1.00 69.13 O +ATOM 215 CB ALA A 29 13.821 -25.028 -3.188 1.00119.04 C +ATOM 216 N PRO A 30 11.969 -23.618 -0.891 1.00 61.30 N +ATOM 217 CA PRO A 30 11.169 -22.435 -0.565 1.00 76.39 C +ATOM 218 C PRO A 30 11.400 -21.252 -1.518 1.00 67.69 C +ATOM 219 O PRO A 30 12.325 -21.290 -2.320 1.00 71.70 O +ATOM 220 CB PRO A 30 11.675 -22.072 0.839 1.00 94.74 C +ATOM 221 CG PRO A 30 13.106 -22.516 0.851 1.00 85.59 C +ATOM 222 CD PRO A 30 13.182 -23.718 -0.057 1.00 71.20 C +ATOM 223 N THR A 31 10.666 -20.160 -1.314 1.00 71.42 N +ATOM 224 CA THR A 31 10.816 -18.960 -2.151 1.00 93.78 C +ATOM 225 C THR A 31 12.150 -18.254 -1.937 1.00 95.53 C +ATOM 226 O THR A 31 12.653 -17.560 -2.825 1.00116.84 O +ATOM 227 CB THR A 31 9.662 -17.935 -1.955 1.00123.11 C +ATOM 228 OG1 THR A 31 9.499 -17.603 -0.568 1.00155.41 O +ATOM 229 CG2 THR A 31 8.347 -18.491 -2.495 1.00132.32 C +ATOM 230 N GLY A 32 12.707 -18.405 -0.746 1.00 94.83 N +ATOM 231 CA GLY A 32 14.061 -17.946 -0.475 1.00116.34 C +ATOM 232 C GLY A 32 14.568 -18.720 0.719 1.00127.31 C +ATOM 233 O GLY A 32 13.803 -19.210 1.532 1.00140.69 O +ATOM 234 N LYS A 33 15.871 -18.810 0.887 1.00125.47 N +ATOM 235 CA LYS A 33 16.376 -19.505 2.051 1.00117.40 C +ATOM 236 C LYS A 33 15.904 -18.746 3.292 1.00110.90 C +ATOM 237 O LYS A 33 15.158 -17.710 3.207 1.00135.50 O +ATOM 238 CB LYS A 33 17.877 -19.517 1.941 1.00108.75 C +ATOM 239 CG LYS A 33 18.234 -20.159 0.633 1.00111.72 C +ATOM 240 CD LYS A 33 19.606 -19.716 0.203 1.00143.89 C +ATOM 241 CE LYS A 33 19.724 -19.738 -1.309 1.00167.61 C +ATOM 242 NZ LYS A 33 21.010 -19.142 -1.765 1.00165.51 N +ATOM 243 N ILE A 34 16.157 -19.377 4.426 1.00 92.13 N +ATOM 244 CA ILE A 34 15.984 -18.693 5.669 1.00 82.25 C +ATOM 245 C ILE A 34 17.293 -18.725 6.467 1.00 80.89 C +ATOM 246 O ILE A 34 18.072 -19.669 6.381 1.00 64.61 O +ATOM 247 CB ILE A 34 14.767 -19.287 6.408 1.00104.09 C +ATOM 248 CG1 ILE A 34 13.480 -19.048 5.603 1.00120.54 C +ATOM 249 CG2 ILE A 34 14.580 -18.668 7.778 1.00124.26 C +ATOM 250 CD1 ILE A 34 12.783 -20.320 5.157 1.00122.59 C +ATOM 251 N PHE A 35 17.576 -17.607 7.136 1.00101.91 N +ATOM 252 CA PHE A 35 18.786 -17.425 7.965 1.00 85.40 C +ATOM 253 C PHE A 35 18.569 -18.029 9.333 1.00 62.12 C +ATOM 254 O PHE A 35 17.636 -17.623 10.035 1.00 94.21 O +ATOM 255 CB PHE A 35 19.056 -15.921 8.163 1.00 94.08 C +ATOM 256 CG PHE A 35 19.887 -15.275 7.081 1.00 93.49 C +ATOM 257 CD1 PHE A 35 21.001 -15.903 6.552 1.00 70.44 C +ATOM 258 CD2 PHE A 35 19.571 -13.991 6.639 1.00 99.97 C +ATOM 259 CE1 PHE A 35 21.717 -15.314 5.535 1.00 59.05 C +ATOM 260 CE2 PHE A 35 20.308 -13.387 5.634 1.00 80.33 C +ATOM 261 CZ PHE A 35 21.403 -14.041 5.106 1.00 65.23 C +ATOM 262 N VAL A 36 19.408 -18.962 9.713 1.00 45.01 N +ATOM 263 CA VAL A 36 19.227 -19.611 10.989 1.00 47.04 C +ATOM 264 C VAL A 36 20.494 -19.638 11.872 1.00 56.02 C +ATOM 265 O VAL A 36 21.619 -19.595 11.371 1.00 81.92 O +ATOM 266 CB VAL A 36 18.777 -21.024 10.755 1.00 43.55 C +ATOM 267 CG1 VAL A 36 19.932 -21.892 10.296 1.00 55.61 C +ATOM 268 CG2 VAL A 36 18.197 -21.589 12.021 1.00 42.76 C +ATOM 269 N SER A 37 20.309 -19.651 13.191 1.00 55.85 N +ATOM 270 CA SER A 37 21.433 -19.654 14.175 1.00 48.69 C +ATOM 271 C SER A 37 21.337 -20.840 15.102 1.00 50.29 C +ATOM 272 O SER A 37 20.238 -21.178 15.542 1.00 83.88 O +ATOM 273 CB SER A 37 21.357 -18.444 15.070 1.00 33.50 C +ATOM 274 OG SER A 37 21.752 -17.296 14.371 1.00 33.50 O +ATOM 275 N VAL A 38 22.411 -21.587 15.245 1.00 44.12 N +ATOM 276 CA VAL A 38 22.383 -22.666 16.213 1.00 49.68 C +ATOM 277 C VAL A 38 23.530 -22.431 17.162 1.00 70.67 C +ATOM 278 O VAL A 38 24.709 -22.408 16.726 1.00126.96 O +ATOM 279 CB VAL A 38 22.581 -24.074 15.602 1.00 57.41 C +ATOM 280 CG1 VAL A 38 22.669 -25.104 16.725 1.00 56.27 C +ATOM 281 CG2 VAL A 38 21.483 -24.457 14.615 1.00 51.38 C +ATOM 282 N TYR A 39 23.207 -22.243 18.443 1.00 62.58 N +ATOM 283 CA TYR A 39 24.212 -21.898 19.464 1.00 48.07 C +ATOM 284 C TYR A 39 24.701 -23.174 20.120 1.00 61.22 C +ATOM 285 O TYR A 39 25.905 -23.454 20.138 1.00106.09 O +ATOM 286 CB TYR A 39 23.647 -20.931 20.477 1.00 38.83 C +ATOM 287 CG TYR A 39 23.787 -19.512 20.052 1.00 38.73 C +ATOM 288 CD1 TYR A 39 22.894 -18.937 19.160 1.00 40.92 C +ATOM 289 CD2 TYR A 39 24.780 -18.697 20.610 1.00 56.90 C +ATOM 290 CE1 TYR A 39 23.007 -17.605 18.796 1.00 60.48 C +ATOM 291 CE2 TYR A 39 24.903 -17.346 20.268 1.00 59.25 C +ATOM 292 CZ TYR A 39 24.022 -16.792 19.378 1.00 62.30 C +ATOM 293 OH TYR A 39 24.141 -15.466 19.013 1.00 40.69 O +ATOM 294 N ASN A 40 23.778 -24.036 20.521 1.00 66.72 N +ATOM 295 CA ASN A 40 24.171 -25.275 21.170 1.00 74.91 C +ATOM 296 C ASN A 40 23.018 -26.256 21.359 1.00 81.00 C +ATOM 297 O ASN A 40 21.962 -25.896 21.883 1.00 91.07 O +ATOM 298 CB ASN A 40 24.805 -24.978 22.532 1.00 76.04 C +ATOM 299 CG ASN A 40 25.637 -26.132 23.041 1.00107.42 C +ATOM 300 OD1 ASN A 40 26.605 -26.588 22.394 1.00122.75 O +ATOM 301 ND2 ASN A 40 25.297 -26.588 24.231 1.00116.47 N +ATOM 302 N ILE A 41 23.259 -27.514 21.012 1.00 83.98 N +ATOM 303 CA ILE A 41 22.373 -28.596 21.397 1.00 90.07 C +ATOM 304 C ILE A 41 23.132 -29.551 22.350 1.00 94.69 C +ATOM 305 O ILE A 41 24.091 -30.212 21.934 1.00 92.13 O +ATOM 306 CB ILE A 41 21.836 -29.363 20.160 1.00 87.33 C +ATOM 307 CG1 ILE A 41 20.680 -28.613 19.499 1.00 67.22 C +ATOM 308 CG2 ILE A 41 21.285 -30.727 20.569 1.00 90.72 C +ATOM 309 CD1 ILE A 41 21.087 -27.349 18.794 1.00 75.75 C +ATOM 310 N GLN A 42 22.659 -29.672 23.602 1.00 77.75 N +ATOM 311 CA GLN A 42 23.391 -30.407 24.642 1.00 72.01 C +ATOM 312 C GLN A 42 23.076 -31.902 24.678 1.00 73.09 C +ATOM 313 O GLN A 42 21.999 -32.325 24.264 1.00 62.78 O +ATOM 314 CB GLN A 42 23.118 -29.815 26.018 1.00 79.73 C +ATOM 315 CG GLN A 42 23.658 -28.407 26.204 1.00104.00 C +ATOM 316 CD GLN A 42 22.671 -27.344 26.661 1.00126.47 C +ATOM 317 OE1 GLN A 42 22.402 -26.404 25.918 1.00115.93 O +ATOM 318 NE2 GLN A 42 22.288 -27.377 27.947 1.00128.11 N +ATOM 319 N ASP A 43 24.037 -32.689 25.173 1.00 75.91 N +ATOM 320 CA ASP A 43 23.803 -34.065 25.557 1.00 76.94 C +ATOM 321 C ASP A 43 23.080 -34.113 26.924 1.00 80.27 C +ATOM 322 O ASP A 43 23.603 -34.657 27.888 1.00 76.66 O +ATOM 323 CB ASP A 43 25.124 -34.821 25.656 1.00 81.42 C +ATOM 324 CG ASP A 43 24.929 -36.343 25.806 1.00115.72 C +ATOM 325 OD1 ASP A 43 24.174 -36.933 25.006 1.00132.49 O +ATOM 326 OD2 ASP A 43 25.545 -36.983 26.700 1.00132.16 O +ATOM 327 N GLU A 44 21.830 -33.632 26.967 1.00 87.21 N +ATOM 328 CA GLU A 44 21.013 -33.613 28.212 1.00 64.85 C +ATOM 329 C GLU A 44 20.635 -35.033 28.704 1.00 64.56 C +ATOM 330 O GLU A 44 19.708 -35.196 29.498 1.00 66.86 O +ATOM 331 CB GLU A 44 19.754 -32.728 28.005 1.00 66.31 C +ATOM 332 CG GLU A 44 19.948 -31.247 28.289 1.00 62.33 C +ATOM 333 CD GLU A 44 18.698 -30.369 28.036 1.00 68.13 C +ATOM 334 OE1 GLU A 44 17.558 -30.735 28.423 1.00 81.11 O +ATOM 335 OE2 GLU A 44 18.840 -29.261 27.453 1.00 73.38 O +ATOM 336 N THR A 45 21.258 -36.060 28.107 1.00 62.16 N +ATOM 337 CA THR A 45 20.806 -37.446 28.248 1.00 78.63 C +ATOM 338 C THR A 45 21.103 -37.967 29.650 1.00 85.48 C +ATOM 339 O THR A 45 20.322 -38.752 30.192 1.00 76.70 O +ATOM 340 CB THR A 45 21.339 -38.397 27.101 1.00 81.84 C +ATOM 341 OG1 THR A 45 20.657 -39.659 27.144 1.00 86.28 O +ATOM 342 CG2 THR A 45 22.821 -38.660 27.222 1.00108.02 C +ATOM 343 N GLY A 46 22.299 -37.675 30.151 1.00 94.15 N +ATOM 344 CA GLY A 46 22.685 -38.088 31.512 1.00 97.21 C +ATOM 345 C GLY A 46 23.356 -39.463 31.611 1.00 90.97 C +ATOM 346 O GLY A 46 23.390 -40.127 32.662 1.00 44.71 O +ATOM 347 N GLN A 47 23.871 -39.933 30.494 1.00 85.39 N +ATOM 348 CA GLN A 47 24.100 -41.328 30.403 1.00 70.23 C +ATOM 349 C GLN A 47 25.477 -41.621 29.884 1.00 63.29 C +ATOM 350 O GLN A 47 25.985 -40.973 28.951 1.00 50.14 O +ATOM 351 CB GLN A 47 23.041 -41.952 29.534 1.00 62.62 C +ATOM 352 CG GLN A 47 21.688 -41.943 30.195 1.00 74.72 C +ATOM 353 CD GLN A 47 21.747 -42.472 31.627 1.00 89.96 C +ATOM 354 OE1 GLN A 47 21.831 -43.675 31.836 1.00 98.89 O +ATOM 355 NE2 GLN A 47 21.566 -41.589 32.601 1.00 69.89 N +ATOM 356 N PHE A 48 26.084 -42.611 30.534 1.00 52.70 N +ATOM 357 CA PHE A 48 27.391 -43.102 30.159 1.00 50.43 C +ATOM 358 C PHE A 48 27.346 -44.605 29.894 1.00 69.69 C +ATOM 359 O PHE A 48 26.375 -45.312 30.225 1.00 58.24 O +ATOM 360 CB PHE A 48 28.378 -42.826 31.266 1.00 48.93 C +ATOM 361 CG PHE A 48 28.602 -41.388 31.484 1.00 42.23 C +ATOM 362 CD1 PHE A 48 27.643 -40.622 32.170 1.00 39.16 C +ATOM 363 CD2 PHE A 48 29.713 -40.804 30.992 1.00 39.24 C +ATOM 364 CE1 PHE A 48 27.776 -39.273 32.337 1.00 36.86 C +ATOM 365 CE2 PHE A 48 29.857 -39.458 31.133 1.00 50.15 C +ATOM 366 CZ PHE A 48 28.883 -38.686 31.791 1.00 47.77 C +ATOM 367 N LYS A 49 28.428 -45.093 29.292 1.00 90.13 N +ATOM 368 CA LYS A 49 28.518 -46.493 28.893 1.00 86.20 C +ATOM 369 C LYS A 49 28.823 -47.345 30.110 1.00 84.06 C +ATOM 370 O LYS A 49 29.512 -46.886 31.034 1.00 75.79 O +ATOM 371 CB LYS A 49 29.575 -46.682 27.800 1.00 83.96 C +ATOM 372 CG LYS A 49 29.202 -45.987 26.496 1.00 89.37 C +ATOM 373 CD LYS A 49 30.070 -46.287 25.279 1.00 88.60 C +ATOM 374 CE LYS A 49 29.394 -45.645 24.059 1.00 89.62 C +ATOM 375 NZ LYS A 49 30.049 -45.874 22.748 1.00 76.62 N +ATOM 376 N PRO A 50 28.245 -48.553 30.145 1.00 86.34 N +ATOM 377 CA PRO A 50 28.442 -49.485 31.239 1.00 89.04 C +ATOM 378 C PRO A 50 29.754 -50.234 31.113 1.00 86.14 C +ATOM 379 O PRO A 50 30.470 -50.120 30.082 1.00 94.39 O +ATOM 380 CB PRO A 50 27.287 -50.460 31.085 1.00 95.28 C +ATOM 381 CG PRO A 50 26.983 -50.444 29.629 1.00104.14 C +ATOM 382 CD PRO A 50 27.284 -49.057 29.150 1.00 95.17 C +ATOM 383 N TYR A 51 30.115 -50.932 32.183 1.00 77.86 N +ATOM 384 CA TYR A 51 31.317 -51.753 32.150 1.00 91.51 C +ATOM 385 C TYR A 51 31.229 -52.658 30.936 1.00 94.76 C +ATOM 386 O TYR A 51 30.160 -53.194 30.658 1.00 79.88 O +ATOM 387 CB TYR A 51 31.428 -52.595 33.418 1.00 93.35 C +ATOM 388 CG TYR A 51 32.784 -53.233 33.553 1.00 99.81 C +ATOM 389 CD1 TYR A 51 33.827 -52.539 34.155 1.00112.91 C +ATOM 390 CD2 TYR A 51 33.037 -54.509 33.077 1.00107.79 C +ATOM 391 CE1 TYR A 51 35.094 -53.077 34.256 1.00115.53 C +ATOM 392 CE2 TYR A 51 34.308 -55.075 33.204 1.00135.33 C +ATOM 393 CZ TYR A 51 35.341 -54.327 33.761 1.00131.98 C +ATOM 394 OH TYR A 51 36.622 -54.821 33.907 1.00148.14 O +ATOM 395 N PRO A 52 32.345 -52.828 30.197 1.00100.36 N +ATOM 396 CA PRO A 52 33.725 -52.388 30.459 1.00 90.98 C +ATOM 397 C PRO A 52 34.175 -51.062 29.854 1.00 91.55 C +ATOM 398 O PRO A 52 35.377 -50.819 29.774 1.00103.49 O +ATOM 399 CB PRO A 52 34.545 -53.500 29.822 1.00109.98 C +ATOM 400 CG PRO A 52 33.725 -53.903 28.631 1.00124.77 C +ATOM 401 CD PRO A 52 32.283 -53.748 29.041 1.00107.96 C +ATOM 402 N ALA A 53 33.245 -50.197 29.469 1.00104.36 N +ATOM 403 CA ALA A 53 33.635 -48.870 28.984 1.00105.31 C +ATOM 404 C ALA A 53 34.310 -48.044 30.076 1.00 97.76 C +ATOM 405 O ALA A 53 34.175 -48.339 31.288 1.00 73.91 O +ATOM 406 CB ALA A 53 32.435 -48.118 28.455 1.00 97.65 C +ATOM 407 N SER A 54 35.046 -47.016 29.652 1.00 87.02 N +ATOM 408 CA SER A 54 35.527 -46.034 30.609 1.00 86.91 C +ATOM 409 C SER A 54 34.307 -45.422 31.307 1.00 90.52 C +ATOM 410 O SER A 54 33.263 -45.190 30.710 1.00 57.83 O +ATOM 411 CB SER A 54 36.396 -44.936 29.967 1.00 67.49 C +ATOM 412 OG SER A 54 36.436 -43.759 30.774 1.00 40.70 O +ATOM 413 N ASN A 55 34.471 -45.166 32.599 1.00 86.08 N +ATOM 414 CA ASN A 55 33.456 -44.509 33.396 1.00 59.79 C +ATOM 415 C ASN A 55 32.950 -43.249 32.724 1.00 64.02 C +ATOM 416 O ASN A 55 31.812 -42.824 32.898 1.00 43.56 O +ATOM 417 CB ASN A 55 34.066 -44.162 34.735 1.00 53.47 C +ATOM 418 CG ASN A 55 33.030 -43.824 35.750 1.00 67.57 C +ATOM 419 OD1 ASN A 55 31.858 -44.184 35.632 1.00104.60 O +ATOM 420 ND2 ASN A 55 33.465 -43.189 36.800 1.00 76.63 N +ATOM 421 N PHE A 56 33.847 -42.624 31.956 1.00 83.94 N +ATOM 422 CA PHE A 56 33.614 -41.282 31.391 1.00 72.92 C +ATOM 423 C PHE A 56 33.106 -41.316 29.962 1.00 68.66 C +ATOM 424 O PHE A 56 32.973 -40.273 29.335 1.00 59.86 O +ATOM 425 CB PHE A 56 34.897 -40.469 31.395 1.00 61.93 C +ATOM 426 CG PHE A 56 35.474 -40.295 32.746 1.00 63.89 C +ATOM 427 CD1 PHE A 56 34.779 -39.674 33.753 1.00 64.11 C +ATOM 428 CD2 PHE A 56 36.704 -40.825 33.017 1.00100.39 C +ATOM 429 CE1 PHE A 56 35.311 -39.562 35.009 1.00 79.28 C +ATOM 430 CE2 PHE A 56 37.281 -40.661 34.263 1.00119.27 C +ATOM 431 CZ PHE A 56 36.571 -40.044 35.267 1.00106.83 C +ATOM 432 N SER A 57 32.960 -42.505 29.396 1.00 72.64 N +ATOM 433 CA SER A 57 32.509 -42.600 28.016 1.00 87.28 C +ATOM 434 C SER A 57 31.005 -42.330 27.975 1.00 88.62 C +ATOM 435 O SER A 57 30.212 -43.060 28.555 1.00 71.93 O +ATOM 436 CB SER A 57 32.846 -43.975 27.418 1.00112.34 C +ATOM 437 OG SER A 57 34.231 -44.067 27.117 1.00116.79 O +ATOM 438 N THR A 58 30.633 -41.240 27.328 1.00 93.73 N +ATOM 439 CA THR A 58 29.248 -40.868 27.236 1.00 80.95 C +ATOM 440 C THR A 58 28.537 -41.784 26.327 1.00 81.57 C +ATOM 441 O THR A 58 29.087 -42.363 25.387 1.00106.08 O +ATOM 442 CB THR A 58 29.092 -39.480 26.643 1.00 96.64 C +ATOM 443 OG1 THR A 58 29.670 -39.429 25.333 1.00 88.40 O +ATOM 444 CG2 THR A 58 29.825 -38.493 27.504 1.00137.80 C +ATOM 445 N ALA A 59 27.264 -41.914 26.552 1.00 93.85 N +ATOM 446 CA ALA A 59 26.564 -42.884 25.741 1.00 98.58 C +ATOM 447 C ALA A 59 26.326 -42.324 24.349 1.00 73.16 C +ATOM 448 O ALA A 59 26.001 -43.054 23.431 1.00 66.16 O +ATOM 449 CB ALA A 59 25.282 -43.304 26.423 1.00 98.98 C +ATOM 450 N VAL A 60 26.425 -41.007 24.230 1.00 69.09 N +ATOM 451 CA VAL A 60 25.963 -40.298 23.044 1.00 72.04 C +ATOM 452 C VAL A 60 27.014 -39.250 22.696 1.00 54.62 C +ATOM 453 O VAL A 60 27.559 -38.620 23.580 1.00 49.58 O +ATOM 454 CB VAL A 60 24.604 -39.572 23.310 1.00 97.26 C +ATOM 455 CG1 VAL A 60 24.139 -38.799 22.083 1.00102.04 C +ATOM 456 CG2 VAL A 60 23.518 -40.557 23.749 1.00107.45 C +ATOM 457 N PRO A 61 27.270 -39.046 21.406 1.00 41.27 N +ATOM 458 CA PRO A 61 28.339 -38.139 21.046 1.00 32.04 C +ATOM 459 C PRO A 61 27.939 -36.765 21.330 1.00 34.85 C +ATOM 460 O PRO A 61 26.727 -36.400 21.214 1.00 35.22 O +ATOM 461 CB PRO A 61 28.483 -38.336 19.546 1.00 35.24 C +ATOM 462 CG PRO A 61 27.197 -39.025 19.102 1.00 44.03 C +ATOM 463 CD PRO A 61 26.814 -39.876 20.262 1.00 46.32 C +ATOM 464 N GLN A 62 28.935 -35.954 21.677 1.00 50.69 N +ATOM 465 CA GLN A 62 28.688 -34.569 22.105 1.00 67.74 C +ATOM 466 C GLN A 62 28.705 -33.634 20.929 1.00 50.34 C +ATOM 467 O GLN A 62 29.109 -32.517 21.062 1.00 51.30 O +ATOM 468 CB GLN A 62 29.749 -34.112 23.123 1.00 82.24 C +ATOM 469 CG GLN A 62 29.975 -35.072 24.293 1.00 95.42 C +ATOM 470 CD GLN A 62 28.721 -35.321 25.109 1.00103.08 C +ATOM 471 OE1 GLN A 62 28.297 -34.475 25.900 1.00102.18 O +ATOM 472 NE2 GLN A 62 28.076 -36.455 24.864 1.00 94.55 N +ATOM 473 N SER A 63 28.124 -34.056 19.823 1.00 64.08 N +ATOM 474 CA SER A 63 28.377 -33.419 18.540 1.00 78.16 C +ATOM 475 C SER A 63 27.089 -33.006 17.837 1.00 96.90 C +ATOM 476 O SER A 63 27.101 -32.576 16.682 1.00 77.84 O +ATOM 477 CB SER A 63 29.196 -34.364 17.639 1.00 83.70 C +ATOM 478 OG SER A 63 28.529 -35.577 17.345 1.00 47.35 O +ATOM 479 N ALA A 64 25.986 -33.077 18.573 1.00120.52 N +ATOM 480 CA ALA A 64 24.667 -32.859 17.993 1.00131.01 C +ATOM 481 C ALA A 64 24.559 -31.492 17.278 1.00111.27 C +ATOM 482 O ALA A 64 23.886 -31.359 16.242 1.00 92.65 O +ATOM 483 CB ALA A 64 23.612 -33.002 19.085 1.00134.13 C +ATOM 484 N THR A 65 25.158 -30.468 17.883 1.00 81.32 N +ATOM 485 CA THR A 65 25.061 -29.092 17.390 1.00 64.82 C +ATOM 486 C THR A 65 25.516 -28.982 15.959 1.00 54.59 C +ATOM 487 O THR A 65 24.812 -28.426 15.115 1.00 88.96 O +ATOM 488 CB THR A 65 25.979 -28.206 18.202 1.00 83.61 C +ATOM 489 OG1 THR A 65 25.913 -28.593 19.584 1.00 97.97 O +ATOM 490 CG2 THR A 65 25.622 -26.736 18.026 1.00 75.64 C +ATOM 491 N ALA A 66 26.643 -29.598 15.662 1.00 50.99 N +ATOM 492 CA ALA A 66 27.192 -29.516 14.344 1.00 68.72 C +ATOM 493 C ALA A 66 26.361 -30.348 13.349 1.00 82.20 C +ATOM 494 O ALA A 66 26.214 -29.963 12.166 1.00111.38 O +ATOM 495 CB ALA A 66 28.634 -29.981 14.362 1.00 94.48 C +ATOM 496 N MET A 67 25.819 -31.474 13.816 1.00 70.56 N +ATOM 497 CA MET A 67 24.953 -32.309 12.964 1.00 72.97 C +ATOM 498 C MET A 67 23.717 -31.516 12.542 1.00 55.93 C +ATOM 499 O MET A 67 23.245 -31.591 11.425 1.00 48.96 O +ATOM 500 CB MET A 67 24.530 -33.583 13.714 1.00 86.00 C +ATOM 501 CG MET A 67 25.629 -34.613 13.940 1.00 91.95 C +ATOM 502 SD MET A 67 25.121 -35.904 15.109 1.00 69.69 S +ATOM 503 CE MET A 67 26.494 -37.035 15.020 1.00 94.40 C +ATOM 504 N LEU A 68 23.156 -30.781 13.489 1.00 51.98 N +ATOM 505 CA LEU A 68 21.958 -30.022 13.217 1.00 49.20 C +ATOM 506 C LEU A 68 22.285 -28.993 12.176 1.00 50.73 C +ATOM 507 O LEU A 68 21.454 -28.710 11.323 1.00 74.80 O +ATOM 508 CB LEU A 68 21.386 -29.364 14.507 1.00 52.36 C +ATOM 509 CG LEU A 68 20.271 -28.350 14.241 1.00 57.51 C +ATOM 510 CD1 LEU A 68 19.035 -29.023 13.663 1.00 63.11 C +ATOM 511 CD2 LEU A 68 19.891 -27.558 15.473 1.00 60.61 C +ATOM 512 N VAL A 69 23.388 -28.271 12.365 1.00 63.67 N +ATOM 513 CA VAL A 69 23.726 -27.145 11.473 1.00 70.52 C +ATOM 514 C VAL A 69 23.886 -27.724 10.077 1.00 57.27 C +ATOM 515 O VAL A 69 23.406 -27.149 9.102 1.00 48.58 O +ATOM 516 CB VAL A 69 25.034 -26.429 11.881 1.00 78.98 C +ATOM 517 CG1 VAL A 69 25.453 -25.462 10.795 1.00 82.20 C +ATOM 518 CG2 VAL A 69 24.883 -25.677 13.194 1.00 84.42 C +ATOM 519 N THR A 70 24.512 -28.893 10.010 1.00 46.30 N +ATOM 520 CA THR A 70 24.756 -29.527 8.744 1.00 63.94 C +ATOM 521 C THR A 70 23.436 -29.955 8.098 1.00 72.48 C +ATOM 522 O THR A 70 23.218 -29.752 6.892 1.00107.14 O +ATOM 523 CB THR A 70 25.660 -30.738 8.931 1.00 94.63 C +ATOM 524 OG1 THR A 70 26.884 -30.316 9.546 1.00108.27 O +ATOM 525 CG2 THR A 70 25.972 -31.400 7.573 1.00125.72 C +ATOM 526 N ALA A 71 22.547 -30.545 8.883 1.00 58.17 N +ATOM 527 CA ALA A 71 21.234 -30.942 8.357 1.00 45.54 C +ATOM 528 C ALA A 71 20.451 -29.704 7.852 1.00 43.59 C +ATOM 529 O ALA A 71 19.782 -29.745 6.842 1.00 37.60 O +ATOM 530 CB ALA A 71 20.444 -31.681 9.442 1.00 49.20 C +ATOM 531 N LEU A 72 20.479 -28.622 8.622 1.00 49.59 N +ATOM 532 CA LEU A 72 19.811 -27.381 8.233 1.00 53.12 C +ATOM 533 C LEU A 72 20.360 -26.866 6.909 1.00 72.19 C +ATOM 534 O LEU A 72 19.679 -26.145 6.205 1.00 74.86 O +ATOM 535 CB LEU A 72 19.997 -26.300 9.307 1.00 55.35 C +ATOM 536 CG LEU A 72 19.278 -26.573 10.616 1.00 57.62 C +ATOM 537 CD1 LEU A 72 19.869 -25.679 11.706 1.00 74.57 C +ATOM 538 CD2 LEU A 72 17.799 -26.340 10.499 1.00 62.11 C +ATOM 539 N LYS A 73 21.620 -27.188 6.599 1.00 89.12 N +ATOM 540 CA LYS A 73 22.236 -26.726 5.348 1.00 81.89 C +ATOM 541 C LYS A 73 21.894 -27.640 4.201 1.00 89.68 C +ATOM 542 O LYS A 73 21.512 -27.171 3.132 1.00110.88 O +ATOM 543 CB LYS A 73 23.756 -26.641 5.456 1.00 81.84 C +ATOM 544 CG LYS A 73 24.401 -25.901 4.287 1.00 85.24 C +ATOM 545 CD LYS A 73 25.921 -25.832 4.433 1.00101.49 C +ATOM 546 CE LYS A 73 26.620 -25.742 3.083 1.00140.36 C +ATOM 547 NZ LYS A 73 27.311 -24.439 2.864 1.00162.23 N +ATOM 548 N ASP A 74 21.986 -28.950 4.436 1.00 91.51 N +ATOM 549 CA ASP A 74 21.697 -29.946 3.390 1.00109.24 C +ATOM 550 C ASP A 74 20.255 -29.883 2.871 1.00109.57 C +ATOM 551 O ASP A 74 20.007 -30.159 1.698 1.00102.23 O +ATOM 552 CB ASP A 74 21.962 -31.354 3.903 1.00121.11 C +ATOM 553 CG ASP A 74 23.443 -31.623 4.170 1.00136.63 C +ATOM 554 OD1 ASP A 74 24.329 -31.026 3.506 1.00126.64 O +ATOM 555 OD2 ASP A 74 23.709 -32.485 5.033 1.00158.01 O +ATOM 556 N SER A 75 19.337 -29.411 3.722 1.00113.42 N +ATOM 557 CA SER A 75 17.919 -29.278 3.365 1.00 90.03 C +ATOM 558 C SER A 75 17.656 -28.259 2.244 1.00 81.58 C +ATOM 559 O SER A 75 16.660 -28.365 1.531 1.00 76.72 O +ATOM 560 CB SER A 75 17.097 -28.871 4.590 1.00 80.03 C +ATOM 561 OG SER A 75 17.070 -27.458 4.747 1.00 63.77 O +ATOM 562 N ARG A 76 18.548 -27.275 2.120 1.00 59.34 N +ATOM 563 CA ARG A 76 18.456 -26.218 1.127 1.00 56.63 C +ATOM 564 C ARG A 76 17.243 -25.376 1.413 1.00 54.76 C +ATOM 565 O ARG A 76 16.610 -24.860 0.500 1.00 46.86 O +ATOM 566 CB ARG A 76 18.415 -26.752 -0.314 1.00 59.53 C +ATOM 567 CG ARG A 76 19.693 -27.315 -0.871 1.00 69.97 C +ATOM 568 CD ARG A 76 20.841 -26.305 -0.852 1.00114.97 C +ATOM 569 NE ARG A 76 20.662 -25.205 -1.815 1.00136.41 N +ATOM 570 CZ ARG A 76 20.176 -23.982 -1.538 1.00107.02 C +ATOM 571 NH1 ARG A 76 19.767 -23.634 -0.316 1.00 82.72 N +ATOM 572 NH2 ARG A 76 20.106 -23.088 -2.516 1.00104.85 N +ATOM 573 N TRP A 77 16.961 -25.210 2.693 1.00 63.47 N +ATOM 574 CA TRP A 77 15.954 -24.263 3.154 1.00 80.07 C +ATOM 575 C TRP A 77 16.585 -23.127 3.989 1.00 82.83 C +ATOM 576 O TRP A 77 16.128 -21.976 3.933 1.00 72.25 O +ATOM 577 CB TRP A 77 14.922 -25.005 4.003 1.00 73.79 C +ATOM 578 CG TRP A 77 13.742 -25.527 3.238 1.00 70.96 C +ATOM 579 CD1 TRP A 77 13.701 -26.625 2.452 1.00 71.05 C +ATOM 580 CD2 TRP A 77 12.420 -24.986 3.240 1.00 68.54 C +ATOM 581 NE1 TRP A 77 12.444 -26.792 1.940 1.00 73.32 N +ATOM 582 CE2 TRP A 77 11.645 -25.779 2.387 1.00 65.57 C +ATOM 583 CE3 TRP A 77 11.832 -23.874 3.850 1.00 79.57 C +ATOM 584 CZ2 TRP A 77 10.316 -25.500 2.114 1.00 69.27 C +ATOM 585 CZ3 TRP A 77 10.501 -23.615 3.610 1.00 84.82 C +ATOM 586 CH2 TRP A 77 9.756 -24.416 2.735 1.00 83.44 C +ATOM 587 N PHE A 78 17.673 -23.456 4.685 1.00 77.63 N +ATOM 588 CA PHE A 78 18.308 -22.549 5.626 1.00 73.30 C +ATOM 589 C PHE A 78 19.774 -22.288 5.317 1.00 66.29 C +ATOM 590 O PHE A 78 20.496 -23.177 4.870 1.00 50.41 O +ATOM 591 CB PHE A 78 18.262 -23.155 7.008 1.00 81.82 C +ATOM 592 CG PHE A 78 16.882 -23.532 7.452 1.00 79.89 C +ATOM 593 CD1 PHE A 78 15.985 -22.572 7.866 1.00 89.17 C +ATOM 594 CD2 PHE A 78 16.508 -24.843 7.515 1.00 72.02 C +ATOM 595 CE1 PHE A 78 14.728 -22.929 8.320 1.00 73.34 C +ATOM 596 CE2 PHE A 78 15.251 -25.198 7.972 1.00 60.61 C +ATOM 597 CZ PHE A 78 14.368 -24.246 8.386 1.00 52.83 C +ATOM 598 N ILE A 79 20.198 -21.046 5.560 1.00 62.00 N +ATOM 599 CA ILE A 79 21.602 -20.682 5.615 1.00 49.51 C +ATOM 600 C ILE A 79 21.950 -20.656 7.075 1.00 42.02 C +ATOM 601 O ILE A 79 21.288 -19.947 7.871 1.00 64.78 O +ATOM 602 CB ILE A 79 21.844 -19.269 5.057 1.00 56.65 C +ATOM 603 CG1 ILE A 79 21.198 -19.112 3.693 1.00 56.59 C +ATOM 604 CG2 ILE A 79 23.343 -18.973 4.960 1.00 76.26 C +ATOM 605 CD1 ILE A 79 20.906 -17.667 3.324 1.00 68.21 C +ATOM 606 N PRO A 80 22.953 -21.430 7.447 1.00 30.98 N +ATOM 607 CA PRO A 80 23.265 -21.336 8.837 1.00 39.18 C +ATOM 608 C PRO A 80 24.275 -20.229 9.057 1.00 42.38 C +ATOM 609 O PRO A 80 25.309 -20.235 8.388 1.00 74.73 O +ATOM 610 CB PRO A 80 23.806 -22.757 9.162 1.00 34.12 C +ATOM 611 CG PRO A 80 23.204 -23.623 8.152 1.00 27.11 C +ATOM 612 CD PRO A 80 23.276 -22.746 6.928 1.00 27.33 C +ATOM 613 N LEU A 81 24.039 -19.403 10.060 1.00 35.28 N +ATOM 614 CA LEU A 81 25.054 -18.552 10.550 1.00 54.53 C +ATOM 615 C LEU A 81 25.896 -19.142 11.697 1.00 75.89 C +ATOM 616 O LEU A 81 25.379 -19.912 12.543 1.00 74.47 O +ATOM 617 CB LEU A 81 24.416 -17.281 11.004 1.00 62.31 C +ATOM 618 CG LEU A 81 23.523 -16.758 9.894 1.00 65.48 C +ATOM 619 CD1 LEU A 81 22.804 -15.543 10.438 1.00 86.99 C +ATOM 620 CD2 LEU A 81 24.336 -16.370 8.693 1.00 73.15 C +ATOM 621 N GLU A 82 27.208 -18.820 11.677 1.00 80.49 N +ATOM 622 CA GLU A 82 28.176 -19.446 12.584 1.00 87.60 C +ATOM 623 C GLU A 82 28.114 -18.762 13.918 1.00 75.18 C +ATOM 624 O GLU A 82 28.608 -17.640 14.073 1.00 77.21 O +ATOM 625 CB GLU A 82 29.628 -19.462 12.026 1.00 88.56 C +ATOM 626 CG GLU A 82 30.695 -20.084 12.955 1.00 85.61 C +ATOM 627 CD GLU A 82 30.595 -21.616 13.149 1.00108.95 C +ATOM 628 OE1 GLU A 82 29.485 -22.175 13.423 1.00137.78 O +ATOM 629 OE2 GLU A 82 31.649 -22.288 13.054 1.00142.30 O +ATOM 630 N ARG A 83 27.588 -19.508 14.898 1.00 73.94 N +ATOM 631 CA ARG A 83 27.599 -19.090 16.289 1.00 72.17 C +ATOM 632 C ARG A 83 28.263 -20.099 17.241 1.00 70.14 C +ATOM 633 O ARG A 83 28.692 -19.720 18.334 1.00 88.31 O +ATOM 634 CB ARG A 83 26.182 -18.797 16.745 1.00 70.04 C +ATOM 635 CG ARG A 83 25.442 -17.785 15.880 1.00 69.81 C +ATOM 636 CD ARG A 83 25.991 -16.365 16.023 1.00 65.38 C +ATOM 637 NE ARG A 83 25.083 -15.417 15.370 1.00 54.39 N +ATOM 638 CZ ARG A 83 25.238 -14.920 14.150 1.00 58.08 C +ATOM 639 NH1 ARG A 83 26.343 -15.160 13.449 1.00 75.59 N +ATOM 640 NH2 ARG A 83 24.267 -14.211 13.617 1.00 55.08 N +ATOM 641 N GLN A 84 28.418 -21.353 16.842 1.00 74.76 N +ATOM 642 CA GLN A 84 29.112 -22.285 17.736 1.00 87.49 C +ATOM 643 C GLN A 84 30.509 -21.760 18.057 1.00 86.07 C +ATOM 644 O GLN A 84 30.978 -21.841 19.186 1.00 99.06 O +ATOM 645 CB GLN A 84 29.157 -23.718 17.181 1.00 86.80 C +ATOM 646 CG GLN A 84 29.144 -24.804 18.262 1.00 84.92 C +ATOM 647 CD GLN A 84 29.257 -26.209 17.691 1.00125.73 C +ATOM 648 OE1 GLN A 84 28.744 -26.495 16.606 1.00173.17 O +ATOM 649 NE2 GLN A 84 29.938 -27.098 18.415 1.00129.70 N +ATOM 650 N GLY A 85 31.199 -21.236 17.060 1.00 85.15 N +ATOM 651 CA GLY A 85 32.537 -20.749 17.312 1.00 79.51 C +ATOM 652 C GLY A 85 32.575 -19.247 17.156 1.00 55.63 C +ATOM 653 O GLY A 85 33.602 -18.703 16.740 1.00 58.73 O +ATOM 654 N LEU A 86 31.567 -18.580 17.695 1.00 45.93 N +ATOM 655 CA LEU A 86 31.437 -17.137 17.529 1.00 52.64 C +ATOM 656 C LEU A 86 32.642 -16.346 18.062 1.00 78.67 C +ATOM 657 O LEU A 86 33.061 -15.350 17.451 1.00 94.71 O +ATOM 658 CB LEU A 86 30.169 -16.618 18.216 1.00 42.30 C +ATOM 659 CG LEU A 86 29.897 -15.145 18.261 1.00 41.74 C +ATOM 660 CD1 LEU A 86 29.797 -14.521 16.860 1.00 53.19 C +ATOM 661 CD2 LEU A 86 28.626 -14.882 19.046 1.00 40.78 C +ATOM 662 N GLN A 87 33.235 -16.813 19.161 1.00 85.84 N +ATOM 663 CA GLN A 87 34.317 -16.071 19.795 1.00 89.48 C +ATOM 664 C GLN A 87 35.553 -15.918 18.868 1.00 94.52 C +ATOM 665 O GLN A 87 36.141 -14.829 18.721 1.00 89.08 O +ATOM 666 CB GLN A 87 34.685 -16.743 21.117 1.00 96.75 C +ATOM 667 CG GLN A 87 35.129 -15.757 22.194 1.00117.30 C +ATOM 668 CD GLN A 87 34.258 -14.500 22.249 1.00103.26 C +ATOM 669 OE1 GLN A 87 33.051 -14.581 22.472 1.00119.69 O +ATOM 670 NE2 GLN A 87 34.882 -13.332 22.101 1.00109.73 N +ATOM 671 N ASN A 88 35.911 -17.011 18.202 1.00 73.86 N +ATOM 672 CA ASN A 88 37.006 -16.997 17.240 1.00 63.45 C +ATOM 673 C ASN A 88 36.728 -16.102 16.046 1.00 73.74 C +ATOM 674 O ASN A 88 37.639 -15.466 15.489 1.00 65.18 O +ATOM 675 CB ASN A 88 37.225 -18.400 16.721 1.00 66.09 C +ATOM 676 CG ASN A 88 37.437 -19.383 17.841 1.00 78.07 C +ATOM 677 OD1 ASN A 88 38.131 -19.069 18.802 1.00 74.51 O +ATOM 678 ND2 ASN A 88 36.896 -20.596 17.695 1.00 77.57 N +ATOM 679 N LEU A 89 35.470 -16.123 15.596 1.00 74.89 N +ATOM 680 CA LEU A 89 35.043 -15.318 14.474 1.00 61.65 C +ATOM 681 C LEU A 89 35.288 -13.819 14.832 1.00 62.43 C +ATOM 682 O LEU A 89 35.817 -13.032 14.025 1.00 61.41 O +ATOM 683 CB LEU A 89 33.582 -15.606 14.190 1.00 61.14 C +ATOM 684 CG LEU A 89 33.054 -15.447 12.768 1.00 75.38 C +ATOM 685 CD1 LEU A 89 32.017 -14.322 12.687 1.00 69.15 C +ATOM 686 CD2 LEU A 89 34.176 -15.202 11.769 1.00 72.89 C +ATOM 687 N LEU A 90 34.964 -13.455 16.066 1.00 62.21 N +ATOM 688 CA LEU A 90 35.078 -12.073 16.492 1.00 70.36 C +ATOM 689 C LEU A 90 36.544 -11.688 16.632 1.00 72.93 C +ATOM 690 O LEU A 90 36.929 -10.513 16.445 1.00 52.80 O +ATOM 691 CB LEU A 90 34.327 -11.870 17.811 1.00 64.47 C +ATOM 692 CG LEU A 90 32.828 -12.154 17.716 1.00 54.76 C +ATOM 693 CD1 LEU A 90 32.301 -12.352 19.112 1.00 63.89 C +ATOM 694 CD2 LEU A 90 32.112 -10.998 17.012 1.00 54.68 C +ATOM 695 N ASN A 91 37.352 -12.684 16.977 1.00 77.00 N +ATOM 696 CA ASN A 91 38.771 -12.474 17.138 1.00 86.23 C +ATOM 697 C ASN A 91 39.441 -12.230 15.792 1.00 75.52 C +ATOM 698 O ASN A 91 40.215 -11.256 15.647 1.00 74.88 O +ATOM 699 CB ASN A 91 39.405 -13.677 17.830 1.00108.17 C +ATOM 700 CG ASN A 91 40.219 -13.267 19.044 1.00111.22 C +ATOM 701 OD1 ASN A 91 39.725 -12.485 19.855 1.00 99.96 O +ATOM 702 ND2 ASN A 91 41.529 -13.584 19.037 1.00119.89 N +ATOM 703 N GLU A 92 39.164 -13.097 14.819 1.00 44.63 N +ATOM 704 CA GLU A 92 39.676 -12.845 13.466 1.00 52.26 C +ATOM 705 C GLU A 92 39.262 -11.464 12.891 1.00 56.33 C +ATOM 706 O GLU A 92 40.039 -10.783 12.204 1.00 42.97 O +ATOM 707 CB GLU A 92 39.227 -13.917 12.496 1.00 56.75 C +ATOM 708 CG GLU A 92 40.172 -15.089 12.392 1.00 63.64 C +ATOM 709 CD GLU A 92 41.623 -14.684 12.070 1.00 82.54 C +ATOM 710 OE1 GLU A 92 41.887 -14.046 11.014 1.00 94.11 O +ATOM 711 OE2 GLU A 92 42.520 -15.081 12.836 1.00 76.05 O +ATOM 712 N ARG A 93 38.053 -11.037 13.231 1.00 62.42 N +ATOM 713 CA ARG A 93 37.587 -9.720 12.838 1.00 66.25 C +ATOM 714 C ARG A 93 38.339 -8.577 13.590 1.00 71.66 C +ATOM 715 O ARG A 93 38.637 -7.539 12.994 1.00 67.24 O +ATOM 716 CB ARG A 93 36.070 -9.629 13.018 1.00 59.29 C +ATOM 717 CG ARG A 93 35.357 -10.506 12.043 1.00 47.19 C +ATOM 718 CD ARG A 93 33.908 -10.742 12.393 1.00 57.11 C +ATOM 719 NE ARG A 93 33.021 -9.916 11.590 1.00 66.49 N +ATOM 720 CZ ARG A 93 32.562 -8.727 11.944 1.00 61.52 C +ATOM 721 NH1 ARG A 93 32.890 -8.176 13.123 1.00 43.15 N +ATOM 722 NH2 ARG A 93 31.690 -8.129 11.124 1.00 69.29 N +ATOM 723 N LYS A 94 38.707 -8.793 14.847 1.00 66.42 N +ATOM 724 CA LYS A 94 39.600 -7.865 15.517 1.00 77.31 C +ATOM 725 C LYS A 94 40.928 -7.746 14.758 1.00 80.85 C +ATOM 726 O LYS A 94 41.501 -6.643 14.646 1.00 67.79 O +ATOM 727 CB LYS A 94 39.880 -8.318 16.949 1.00 94.08 C +ATOM 728 CG LYS A 94 38.860 -7.852 17.968 1.00134.92 C +ATOM 729 CD LYS A 94 39.117 -8.519 19.313 1.00166.24 C +ATOM 730 CE LYS A 94 38.472 -7.778 20.483 1.00177.46 C +ATOM 731 NZ LYS A 94 38.454 -8.640 21.697 1.00179.41 N +ATOM 732 N ILE A 95 41.466 -8.890 14.316 1.00 72.24 N +ATOM 733 CA ILE A 95 42.801 -8.908 13.711 1.00 69.68 C +ATOM 734 C ILE A 95 42.800 -8.255 12.354 1.00 53.93 C +ATOM 735 O ILE A 95 43.745 -7.505 12.004 1.00 40.73 O +ATOM 736 CB ILE A 95 43.382 -10.315 13.547 1.00 78.57 C +ATOM 737 CG1 ILE A 95 43.262 -11.116 14.847 1.00 66.81 C +ATOM 738 CG2 ILE A 95 44.859 -10.182 13.187 1.00116.15 C +ATOM 739 CD1 ILE A 95 44.097 -12.381 14.894 1.00 69.29 C +ATOM 740 N ILE A 96 41.724 -8.538 11.618 1.00 51.59 N +ATOM 741 CA ILE A 96 41.424 -7.818 10.387 1.00 52.69 C +ATOM 742 C ILE A 96 41.423 -6.305 10.634 1.00 52.86 C +ATOM 743 O ILE A 96 42.199 -5.581 10.002 1.00 78.12 O +ATOM 744 CB ILE A 96 40.090 -8.235 9.734 1.00 36.18 C +ATOM 745 CG1 ILE A 96 40.149 -9.677 9.296 1.00 31.71 C +ATOM 746 CG2 ILE A 96 39.815 -7.375 8.517 1.00 28.76 C +ATOM 747 CD1 ILE A 96 38.897 -10.124 8.602 1.00 33.37 C +ATOM 748 N ARG A 97 40.575 -5.842 11.535 1.00 51.20 N +ATOM 749 CA ARG A 97 40.387 -4.405 11.722 1.00 78.01 C +ATOM 750 C ARG A 97 41.679 -3.759 12.187 1.00 74.32 C +ATOM 751 O ARG A 97 41.946 -2.586 11.896 1.00 59.36 O +ATOM 752 CB ARG A 97 39.270 -4.118 12.730 1.00105.54 C +ATOM 753 CG ARG A 97 37.954 -3.644 12.116 1.00107.90 C +ATOM 754 CD ARG A 97 36.931 -3.325 13.203 1.00128.86 C +ATOM 755 NE ARG A 97 36.255 -4.519 13.714 1.00121.60 N +ATOM 756 CZ ARG A 97 35.057 -4.942 13.313 1.00136.28 C +ATOM 757 NH1 ARG A 97 34.370 -4.270 12.378 1.00128.85 N +ATOM 758 NH2 ARG A 97 34.547 -6.061 13.834 1.00117.96 N +ATOM 759 N ALA A 98 42.498 -4.531 12.894 1.00 76.46 N +ATOM 760 CA ALA A 98 43.789 -4.020 13.364 1.00 96.53 C +ATOM 761 C ALA A 98 44.816 -3.976 12.241 1.00 72.71 C +ATOM 762 O ALA A 98 45.690 -3.105 12.216 1.00 46.97 O +ATOM 763 CB ALA A 98 44.300 -4.881 14.492 1.00114.64 C +ATOM 764 N ALA A 99 44.618 -4.855 11.262 1.00 81.44 N +ATOM 765 CA ALA A 99 45.472 -4.893 10.075 1.00 87.28 C +ATOM 766 C ALA A 99 45.298 -3.656 9.186 1.00 81.33 C +ATOM 767 O ALA A 99 46.275 -3.038 8.764 1.00103.86 O +ATOM 768 CB ALA A 99 45.213 -6.165 9.270 1.00 90.60 C +ATOM 769 N GLN A 100 44.057 -3.338 8.858 1.00 70.23 N +ATOM 770 CA GLN A 100 43.782 -2.464 7.728 1.00 86.63 C +ATOM 771 C GLN A 100 43.313 -1.092 8.138 1.00 83.26 C +ATOM 772 O GLN A 100 42.907 -0.284 7.285 1.00117.29 O +ATOM 773 CB GLN A 100 42.774 -3.113 6.745 1.00 95.90 C +ATOM 774 CG GLN A 100 41.607 -3.827 7.390 1.00 74.81 C +ATOM 775 CD GLN A 100 41.049 -4.948 6.535 1.00 64.22 C +ATOM 776 OE1 GLN A 100 41.739 -5.929 6.177 1.00 39.22 O +ATOM 777 NE2 GLN A 100 39.773 -4.802 6.194 1.00 65.21 N +ATOM 778 N GLU A 101 43.353 -0.821 9.429 1.00 87.72 N +ATOM 779 CA GLU A 101 42.849 0.458 9.934 1.00118.01 C +ATOM 780 C GLU A 101 43.706 1.634 9.478 1.00118.21 C +ATOM 781 O GLU A 101 43.235 2.782 9.445 1.00101.44 O +ATOM 782 CB GLU A 101 42.729 0.431 11.463 1.00124.69 C +ATOM 783 CG GLU A 101 43.983 -0.035 12.190 1.00115.45 C +ATOM 784 CD GLU A 101 43.838 0.039 13.701 1.00103.19 C +ATOM 785 OE1 GLU A 101 42.692 0.118 14.184 1.00107.28 O +ATOM 786 OE2 GLU A 101 44.865 0.001 14.412 1.00104.76 O +ATOM 787 N ASN A 102 44.964 1.362 9.146 1.00112.41 N +ATOM 788 CA ASN A 102 45.875 2.433 8.771 1.00123.02 C +ATOM 789 C ASN A 102 45.913 2.705 7.277 1.00132.73 C +ATOM 790 O ASN A 102 46.628 3.598 6.827 1.00148.33 O +ATOM 791 CB ASN A 102 47.271 2.124 9.286 1.00117.65 C +ATOM 792 CG ASN A 102 47.360 2.260 10.788 1.00110.79 C +ATOM 793 OD1 ASN A 102 47.488 3.374 11.320 1.00111.67 O +ATOM 794 ND2 ASN A 102 47.274 1.131 11.485 1.00100.12 N +ATOM 795 N GLY A 103 45.176 1.920 6.504 1.00140.08 N +ATOM 796 CA GLY A 103 45.179 2.070 5.049 1.00145.59 C +ATOM 797 C GLY A 103 46.537 1.889 4.386 1.00134.72 C +ATOM 798 O GLY A 103 46.867 2.564 3.407 1.00186.02 O +ATOM 799 N THR A 104 47.355 1.015 4.948 1.00108.26 N +ATOM 800 CA THR A 104 48.574 0.623 4.286 1.00106.71 C +ATOM 801 C THR A 104 48.339 -0.696 3.600 1.00100.54 C +ATOM 802 O THR A 104 49.015 -1.002 2.636 1.00101.04 O +ATOM 803 CB THR A 104 49.784 0.548 5.259 1.00133.48 C +ATOM 804 OG1 THR A 104 49.591 -0.463 6.263 1.00107.57 O +ATOM 805 CG2 THR A 104 50.002 1.907 5.942 1.00143.87 C +ATOM 806 N VAL A 105 47.408 -1.502 4.116 1.00104.33 N +ATOM 807 CA VAL A 105 47.299 -2.912 3.682 1.00120.79 C +ATOM 808 C VAL A 105 46.973 -2.937 2.189 1.00145.04 C +ATOM 809 O VAL A 105 46.211 -2.095 1.690 1.00123.23 O +ATOM 810 CB VAL A 105 46.283 -3.767 4.524 1.00 91.58 C +ATOM 811 CG1 VAL A 105 45.541 -4.772 3.653 1.00 94.03 C +ATOM 812 CG2 VAL A 105 46.984 -4.501 5.683 1.00 66.23 C +ATOM 813 N ALA A 106 47.595 -3.896 1.495 1.00153.18 N +ATOM 814 CA ALA A 106 47.558 -3.988 0.039 1.00136.13 C +ATOM 815 C ALA A 106 46.139 -4.212 -0.457 1.00142.11 C +ATOM 816 O ALA A 106 45.407 -5.038 0.093 1.00187.65 O +ATOM 817 CB ALA A 106 48.465 -5.116 -0.429 1.00140.97 C +ATOM 818 N ILE A 107 45.750 -3.451 -1.478 1.00143.11 N +ATOM 819 CA ILE A 107 44.366 -3.436 -1.971 1.00143.22 C +ATOM 820 C ILE A 107 43.876 -4.833 -2.414 1.00143.41 C +ATOM 821 O ILE A 107 42.692 -5.155 -2.302 1.00115.91 O +ATOM 822 CB ILE A 107 44.208 -2.413 -3.129 1.00138.74 C +ATOM 823 CG1 ILE A 107 42.728 -2.163 -3.452 1.00120.24 C +ATOM 824 CG2 ILE A 107 44.960 -2.881 -4.370 1.00141.71 C +ATOM 825 CD1 ILE A 107 41.906 -1.671 -2.278 1.00121.34 C +ATOM 826 N ASN A 108 44.798 -5.662 -2.896 1.00157.05 N +ATOM 827 CA ASN A 108 44.492 -7.056 -3.253 1.00158.34 C +ATOM 828 C ASN A 108 44.229 -7.901 -2.012 1.00148.50 C +ATOM 829 O ASN A 108 43.411 -8.817 -2.029 1.00131.23 O +ATOM 830 CB ASN A 108 45.657 -7.678 -4.029 1.00168.73 C +ATOM 831 CG ASN A 108 46.423 -6.655 -4.847 1.00205.34 C +ATOM 832 OD1 ASN A 108 46.069 -6.369 -5.990 1.00223.88 O +ATOM 833 ND2 ASN A 108 47.486 -6.100 -4.263 1.00226.81 N +ATOM 834 N ASN A 109 44.959 -7.591 -0.947 1.00135.18 N +ATOM 835 CA ASN A 109 44.926 -8.362 0.287 1.00115.71 C +ATOM 836 C ASN A 109 43.823 -7.923 1.251 1.00104.78 C +ATOM 837 O ASN A 109 43.442 -8.685 2.147 1.00131.86 O +ATOM 838 CB ASN A 109 46.271 -8.258 0.994 1.00111.26 C +ATOM 839 CG ASN A 109 46.972 -9.594 1.095 1.00133.37 C +ATOM 840 OD1 ASN A 109 47.171 -10.123 2.189 1.00124.99 O +ATOM 841 ND2 ASN A 109 47.333 -10.163 -0.056 1.00146.45 N +ATOM 842 N ARG A 110 43.283 -6.729 1.015 1.00 83.00 N +ATOM 843 CA ARG A 110 42.278 -6.119 1.876 1.00 72.87 C +ATOM 844 C ARG A 110 41.063 -7.039 2.065 1.00 87.85 C +ATOM 845 O ARG A 110 40.526 -7.593 1.099 1.00 86.07 O +ATOM 846 CB ARG A 110 41.808 -4.791 1.248 1.00 84.19 C +ATOM 847 CG ARG A 110 41.247 -3.779 2.229 1.00101.83 C +ATOM 848 CD ARG A 110 41.584 -2.345 1.840 1.00114.45 C +ATOM 849 NE ARG A 110 40.577 -1.744 0.959 1.00130.14 N +ATOM 850 CZ ARG A 110 39.872 -0.634 1.234 1.00131.13 C +ATOM 851 NH1 ARG A 110 40.039 0.029 2.381 1.00108.44 N +ATOM 852 NH2 ARG A 110 38.998 -0.175 0.343 1.00119.09 N +ATOM 853 N ILE A 111 40.598 -7.174 3.307 1.00106.17 N +ATOM 854 CA ILE A 111 39.338 -7.910 3.596 1.00 88.75 C +ATOM 855 C ILE A 111 38.240 -6.943 4.009 1.00 87.46 C +ATOM 856 O ILE A 111 38.384 -6.287 5.026 1.00 83.88 O +ATOM 857 CB ILE A 111 39.507 -8.944 4.726 1.00 75.69 C +ATOM 858 CG1 ILE A 111 40.512 -9.996 4.266 1.00110.63 C +ATOM 859 CG2 ILE A 111 38.182 -9.582 5.058 1.00 55.20 C +ATOM 860 CD1 ILE A 111 41.002 -10.914 5.364 1.00115.12 C +ATOM 861 N PRO A 112 37.159 -6.837 3.210 1.00 90.77 N +ATOM 862 CA PRO A 112 36.101 -5.876 3.491 1.00 79.85 C +ATOM 863 C PRO A 112 35.144 -6.429 4.529 1.00 87.94 C +ATOM 864 O PRO A 112 34.744 -7.605 4.444 1.00 80.99 O +ATOM 865 CB PRO A 112 35.396 -5.743 2.160 1.00 89.43 C +ATOM 866 CG PRO A 112 35.565 -7.087 1.513 1.00103.32 C +ATOM 867 CD PRO A 112 36.848 -7.675 2.034 1.00105.56 C +ATOM 868 N LEU A 113 34.916 -5.640 5.580 1.00107.26 N +ATOM 869 CA LEU A 113 34.205 -6.113 6.773 1.00 88.64 C +ATOM 870 C LEU A 113 32.847 -5.506 6.847 1.00 97.91 C +ATOM 871 O LEU A 113 32.635 -4.296 6.598 1.00 93.77 O +ATOM 872 CB LEU A 113 34.947 -5.805 8.068 1.00 73.18 C +ATOM 873 CG LEU A 113 35.956 -6.852 8.499 1.00 75.68 C +ATOM 874 CD1 LEU A 113 36.531 -6.423 9.826 1.00 95.02 C +ATOM 875 CD2 LEU A 113 35.392 -8.247 8.594 1.00 64.93 C +ATOM 876 N GLN A 114 31.928 -6.375 7.217 1.00 93.71 N +ATOM 877 CA GLN A 114 30.523 -6.095 7.098 1.00 95.65 C +ATOM 878 C GLN A 114 29.937 -6.698 8.343 1.00 80.89 C +ATOM 879 O GLN A 114 30.506 -7.632 8.895 1.00 66.33 O +ATOM 880 CB GLN A 114 29.936 -6.753 5.838 1.00 84.01 C +ATOM 881 CG GLN A 114 28.793 -5.966 5.188 1.00 76.21 C +ATOM 882 CD GLN A 114 27.938 -6.779 4.196 1.00 78.04 C +ATOM 883 OE1 GLN A 114 26.781 -6.410 3.821 1.00 61.50 O +ATOM 884 NE2 GLN A 114 28.484 -7.919 3.792 1.00 71.34 N +ATOM 885 N SER A 115 28.861 -6.086 8.828 1.00 76.35 N +ATOM 886 CA SER A 115 28.297 -6.429 10.126 1.00 68.97 C +ATOM 887 C SER A 115 27.880 -7.861 10.075 1.00 70.29 C +ATOM 888 O SER A 115 27.696 -8.418 8.956 1.00 79.26 O +ATOM 889 CB SER A 115 27.090 -5.551 10.432 1.00 68.99 C +ATOM 890 OG SER A 115 26.179 -5.520 9.327 1.00 67.29 O +ATOM 891 N LEU A 116 27.816 -8.507 11.237 1.00 64.45 N +ATOM 892 CA LEU A 116 27.692 -9.950 11.198 1.00 76.74 C +ATOM 893 C LEU A 116 26.257 -10.260 10.777 1.00 84.30 C +ATOM 894 O LEU A 116 25.350 -9.661 11.336 1.00 66.66 O +ATOM 895 CB LEU A 116 27.994 -10.572 12.539 1.00 66.31 C +ATOM 896 CG LEU A 116 29.435 -10.506 13.036 1.00 59.15 C +ATOM 897 CD1 LEU A 116 29.612 -9.290 13.947 1.00 68.78 C +ATOM 898 CD2 LEU A 116 29.770 -11.803 13.778 1.00 52.11 C +ATOM 899 N THR A 117 26.081 -11.074 9.720 1.00 73.91 N +ATOM 900 CA THR A 117 24.757 -11.396 9.175 1.00 62.57 C +ATOM 901 C THR A 117 23.967 -11.986 10.281 1.00 61.49 C +ATOM 902 O THR A 117 24.487 -12.823 11.041 1.00 43.67 O +ATOM 903 CB THR A 117 24.818 -12.455 8.072 1.00 67.48 C +ATOM 904 OG1 THR A 117 25.703 -12.008 7.045 1.00121.00 O +ATOM 905 CG2 THR A 117 23.455 -12.682 7.479 1.00 73.02 C +ATOM 906 N ALA A 118 22.741 -11.485 10.444 1.00 73.81 N +ATOM 907 CA ALA A 118 21.939 -11.787 11.645 1.00 85.73 C +ATOM 908 C ALA A 118 20.713 -12.599 11.346 1.00 59.39 C +ATOM 909 O ALA A 118 20.022 -12.332 10.352 1.00 42.36 O +ATOM 910 CB ALA A 118 21.517 -10.510 12.347 1.00116.34 C +ATOM 911 N ALA A 119 20.441 -13.548 12.247 1.00 44.90 N +ATOM 912 CA ALA A 119 19.392 -14.542 12.041 1.00 60.61 C +ATOM 913 C ALA A 119 18.033 -14.046 12.510 1.00 80.45 C +ATOM 914 O ALA A 119 17.960 -13.155 13.378 1.00 57.13 O +ATOM 915 CB ALA A 119 19.733 -15.810 12.771 1.00 57.86 C +ATOM 916 N ASN A 120 16.954 -14.598 11.928 1.00 89.20 N +ATOM 917 CA ASN A 120 15.599 -14.248 12.387 1.00 98.07 C +ATOM 918 C ASN A 120 15.041 -15.281 13.351 1.00 73.65 C +ATOM 919 O ASN A 120 14.448 -14.950 14.374 1.00 60.25 O +ATOM 920 CB ASN A 120 14.619 -14.065 11.218 1.00104.76 C +ATOM 921 CG ASN A 120 13.203 -13.704 11.685 1.00116.92 C +ATOM 922 OD1 ASN A 120 13.014 -12.985 12.689 1.00115.30 O +ATOM 923 ND2 ASN A 120 12.198 -14.238 10.978 1.00102.17 N +ATOM 924 N ILE A 121 15.187 -16.541 12.991 1.00 60.82 N +ATOM 925 CA ILE A 121 14.777 -17.612 13.882 1.00 53.87 C +ATOM 926 C ILE A 121 16.042 -18.285 14.292 1.00 51.07 C +ATOM 927 O ILE A 121 16.968 -18.447 13.503 1.00 51.66 O +ATOM 928 CB ILE A 121 13.771 -18.612 13.222 1.00 55.75 C +ATOM 929 CG1 ILE A 121 14.435 -19.508 12.169 1.00 45.35 C +ATOM 930 CG2 ILE A 121 12.578 -17.857 12.600 1.00 66.23 C +ATOM 931 CD1 ILE A 121 14.551 -20.924 12.597 1.00 40.94 C +ATOM 932 N MET A 122 16.123 -18.619 15.548 1.00 52.45 N +ATOM 933 CA MET A 122 17.141 -19.547 15.947 1.00 73.00 C +ATOM 934 C MET A 122 16.520 -20.841 16.517 1.00 68.42 C +ATOM 935 O MET A 122 15.441 -20.827 17.079 1.00120.02 O +ATOM 936 CB MET A 122 18.094 -18.873 16.928 1.00 86.58 C +ATOM 937 CG MET A 122 17.451 -18.334 18.188 1.00143.06 C +ATOM 938 SD MET A 122 18.680 -18.256 19.531 1.00133.88 S +ATOM 939 CE MET A 122 17.643 -18.893 20.880 1.00172.99 C +ATOM 940 N VAL A 123 17.153 -21.973 16.240 1.00 58.91 N +ATOM 941 CA VAL A 123 16.637 -23.279 16.645 1.00 46.26 C +ATOM 942 C VAL A 123 17.595 -23.913 17.588 1.00 46.36 C +ATOM 943 O VAL A 123 18.777 -24.085 17.267 1.00 49.81 O +ATOM 944 CB VAL A 123 16.402 -24.266 15.445 1.00 34.59 C +ATOM 945 CG1 VAL A 123 17.487 -24.157 14.416 1.00 30.38 C +ATOM 946 CG2 VAL A 123 16.229 -25.693 15.929 1.00 27.63 C +ATOM 947 N GLU A 124 17.094 -24.262 18.757 1.00 49.88 N +ATOM 948 CA GLU A 124 17.890 -25.038 19.684 1.00 70.77 C +ATOM 949 C GLU A 124 17.181 -26.295 20.102 1.00 64.73 C +ATOM 950 O GLU A 124 15.998 -26.446 19.856 1.00106.06 O +ATOM 951 CB GLU A 124 18.278 -24.201 20.908 1.00 77.78 C +ATOM 952 CG GLU A 124 17.301 -23.116 21.286 1.00 59.24 C +ATOM 953 CD GLU A 124 17.951 -22.094 22.189 1.00 71.10 C +ATOM 954 OE1 GLU A 124 19.158 -21.798 22.026 1.00 56.09 O +ATOM 955 OE2 GLU A 124 17.265 -21.630 23.123 1.00107.21 O +ATOM 956 N GLY A 125 17.921 -27.187 20.754 1.00 63.38 N +ATOM 957 CA GLY A 125 17.363 -28.429 21.196 1.00 72.13 C +ATOM 958 C GLY A 125 18.330 -29.190 22.071 1.00 71.38 C +ATOM 959 O GLY A 125 19.170 -28.593 22.756 1.00 74.23 O +ATOM 960 N SER A 126 18.101 -30.494 22.194 1.00 58.25 N +ATOM 961 CA SER A 126 18.774 -31.266 23.230 1.00 66.66 C +ATOM 962 C SER A 126 18.649 -32.701 22.891 1.00 63.44 C +ATOM 963 O SER A 126 17.628 -33.121 22.361 1.00 77.80 O +ATOM 964 CB SER A 126 18.196 -31.045 24.660 1.00 77.05 C +ATOM 965 OG SER A 126 17.649 -29.735 24.877 1.00 82.88 O +ATOM 966 N ILE A 127 19.673 -33.471 23.217 1.00 70.11 N +ATOM 967 CA ILE A 127 19.518 -34.916 23.194 1.00 83.26 C +ATOM 968 C ILE A 127 18.799 -35.297 24.484 1.00 80.69 C +ATOM 969 O ILE A 127 19.422 -35.321 25.530 1.00124.46 O +ATOM 970 CB ILE A 127 20.873 -35.669 23.038 1.00 79.38 C +ATOM 971 CG1 ILE A 127 21.506 -35.372 21.668 1.00 90.99 C +ATOM 972 CG2 ILE A 127 20.672 -37.177 23.207 1.00 62.04 C +ATOM 973 CD1 ILE A 127 23.017 -35.395 21.666 1.00101.42 C +ATOM 974 N ILE A 128 17.513 -35.607 24.380 1.00 69.43 N +ATOM 975 CA ILE A 128 16.657 -35.886 25.551 1.00 74.33 C +ATOM 976 C ILE A 128 16.383 -37.276 26.059 1.00 87.72 C +ATOM 977 O ILE A 128 15.307 -37.530 26.656 1.00148.31 O +ATOM 978 CB ILE A 128 15.272 -35.300 25.346 1.00 99.17 C +ATOM 979 CG1 ILE A 128 14.677 -35.724 23.992 1.00104.10 C +ATOM 980 CG2 ILE A 128 15.329 -33.800 25.346 1.00114.08 C +ATOM 981 CD1 ILE A 128 13.156 -35.722 23.958 1.00 94.16 C +ATOM 982 N GLY A 129 17.427 -38.073 26.086 1.00 98.46 N +ATOM 983 CA GLY A 129 17.387 -39.456 26.581 1.00103.89 C +ATOM 984 C GLY A 129 18.134 -40.442 25.718 1.00103.38 C +ATOM 985 O GLY A 129 18.175 -40.324 24.487 1.00102.72 O +ATOM 986 N TYR A 130 18.830 -41.350 26.394 1.00106.85 N +ATOM 987 CA TYR A 130 19.326 -42.565 25.766 1.00102.75 C +ATOM 988 C TYR A 130 19.082 -43.661 26.775 1.00 92.94 C +ATOM 989 O TYR A 130 19.721 -43.691 27.798 1.00121.64 O +ATOM 990 CB TYR A 130 20.830 -42.440 25.429 1.00 88.20 C +ATOM 991 CG TYR A 130 21.483 -43.696 24.882 1.00 70.71 C +ATOM 992 CD1 TYR A 130 21.600 -44.841 25.657 1.00 77.71 C +ATOM 993 CD2 TYR A 130 21.997 -43.724 23.577 1.00 82.47 C +ATOM 994 CE1 TYR A 130 22.248 -45.973 25.164 1.00100.43 C +ATOM 995 CE2 TYR A 130 22.593 -44.862 23.055 1.00104.44 C +ATOM 996 CZ TYR A 130 22.729 -45.978 23.855 1.00113.58 C +ATOM 997 OH TYR A 130 23.358 -47.085 23.327 1.00128.73 O +ATOM 998 N GLU A 131 18.127 -44.534 26.471 1.00 82.85 N +ATOM 999 CA GLU A 131 17.856 -45.711 27.282 1.00 82.60 C +ATOM 1000 C GLU A 131 18.536 -46.886 26.600 1.00 78.32 C +ATOM 1001 O GLU A 131 18.581 -46.951 25.372 1.00 79.28 O +ATOM 1002 CB GLU A 131 16.352 -45.957 27.393 1.00116.32 C +ATOM 1003 CG GLU A 131 15.632 -44.994 28.323 1.00133.15 C +ATOM 1004 CD GLU A 131 16.518 -44.503 29.451 1.00123.21 C +ATOM 1005 OE1 GLU A 131 16.692 -45.246 30.439 1.00147.78 O +ATOM 1006 OE2 GLU A 131 17.039 -43.372 29.350 1.00 44.14 O +ATOM 1007 N SER A 132 19.078 -47.807 27.387 1.00100.32 N +ATOM 1008 CA SER A 132 19.893 -48.884 26.808 1.00110.39 C +ATOM 1009 C SER A 132 19.278 -50.274 27.043 1.00117.04 C +ATOM 1010 O SER A 132 18.775 -50.566 28.138 1.00155.37 O +ATOM 1011 CB SER A 132 21.319 -48.824 27.370 1.00102.20 C +ATOM 1012 OG SER A 132 21.605 -49.950 28.193 1.00126.85 O +ATOM 1013 N ASN A 133 19.390 -51.147 26.043 1.00111.82 N +ATOM 1014 CA ASN A 133 18.696 -52.443 26.051 1.00141.63 C +ATOM 1015 C ASN A 133 17.239 -52.266 26.439 1.00156.06 C +ATOM 1016 O ASN A 133 16.744 -52.889 27.384 1.00161.43 O +ATOM 1017 CB ASN A 133 19.363 -53.453 26.991 1.00135.17 C +ATOM 1018 CG ASN A 133 20.805 -53.738 26.602 1.00141.02 C +ATOM 1019 OD1 ASN A 133 21.179 -53.693 25.424 1.00129.47 O +ATOM 1020 ND2 ASN A 133 21.619 -54.039 27.596 1.00156.98 N +ATOM 1021 N VAL A 134 16.555 -51.429 25.668 1.00159.98 N +ATOM 1022 CA VAL A 134 15.137 -51.162 25.868 1.00136.53 C +ATOM 1023 C VAL A 134 14.379 -52.444 25.520 1.00104.77 C +ATOM 1024 O VAL A 134 13.389 -52.786 26.167 1.00 66.28 O +ATOM 1025 CB VAL A 134 14.669 -49.971 24.993 1.00129.79 C +ATOM 1026 CG1 VAL A 134 13.218 -49.641 25.258 1.00114.69 C +ATOM 1027 CG2 VAL A 134 15.537 -48.740 25.255 1.00132.37 C +ATOM 1028 N LYS A 135 14.892 -53.170 24.527 1.00 95.99 N +ATOM 1029 CA LYS A 135 14.493 -54.555 24.314 1.00 97.19 C +ATOM 1030 C LYS A 135 15.678 -55.439 24.017 1.00100.92 C +ATOM 1031 O LYS A 135 16.746 -54.967 23.582 1.00105.15 O +ATOM 1032 CB LYS A 135 13.511 -54.651 23.150 1.00121.08 C +ATOM 1033 CG LYS A 135 12.203 -53.908 23.388 1.00135.83 C +ATOM 1034 CD LYS A 135 11.320 -53.961 22.150 1.00125.79 C +ATOM 1035 CE LYS A 135 10.016 -53.223 22.355 1.00125.10 C +ATOM 1036 NZ LYS A 135 8.998 -53.681 21.379 1.00114.45 N +ATOM 1037 N SER A 136 15.475 -56.738 24.210 1.00118.50 N +ATOM 1038 CA SER A 136 16.519 -57.721 23.940 1.00141.06 C +ATOM 1039 C SER A 136 15.947 -59.133 23.829 1.00113.77 C +ATOM 1040 O SER A 136 14.900 -59.422 24.397 1.00 91.30 O +ATOM 1041 CB SER A 136 17.616 -57.655 25.016 1.00155.57 C +ATOM 1042 OG SER A 136 17.835 -58.927 25.621 1.00212.49 O +ATOM 1043 N GLY A 137 16.662 -60.011 23.124 1.00102.14 N +ATOM 1044 CA GLY A 137 16.259 -61.414 23.019 1.00103.34 C +ATOM 1045 C GLY A 137 17.306 -62.325 22.422 1.00113.75 C +ATOM 1046 O GLY A 137 18.393 -61.883 22.059 1.00104.50 O +ATOM 1047 N GLY A 138 17.000 -63.620 22.355 1.00154.03 N +ATOM 1048 CA GLY A 138 17.954 -64.612 21.841 1.00193.04 C +ATOM 1049 C GLY A 138 17.331 -65.968 21.539 1.00164.21 C +ATOM 1050 O GLY A 138 16.412 -66.400 22.240 1.00 91.34 O +ATOM 1051 N VAL A 139 17.859 -66.634 20.508 1.00139.51 N +ATOM 1052 CA VAL A 139 17.441 -67.978 20.161 1.00121.94 C +ATOM 1053 C VAL A 139 18.645 -68.816 19.758 1.00122.28 C +ATOM 1054 O VAL A 139 19.416 -68.445 18.866 1.00100.51 O +ATOM 1055 CB VAL A 139 16.450 -67.974 18.994 1.00142.62 C +ATOM 1056 CG1 VAL A 139 16.128 -69.399 18.576 1.00144.02 C +ATOM 1057 CG2 VAL A 139 15.172 -67.224 19.366 1.00167.73 C +ATOM 1058 N GLY A 140 18.789 -69.973 20.400 1.00140.46 N +ATOM 1059 CA GLY A 140 19.917 -70.870 20.134 1.00142.31 C +ATOM 1060 C GLY A 140 19.607 -72.335 20.356 1.00136.99 C +ATOM 1061 O GLY A 140 18.857 -72.693 21.268 1.00153.27 O +ATOM 1062 N ALA A 141 20.235 -73.190 19.557 1.00136.24 N +ATOM 1063 CA ALA A 141 20.135 -74.628 19.763 1.00138.75 C +ATOM 1064 C ALA A 141 21.454 -75.344 19.470 1.00141.23 C +ATOM 1065 O ALA A 141 22.176 -75.007 18.531 1.00127.72 O +ATOM 1066 CB ALA A 141 19.011 -75.202 18.916 1.00131.08 C +ATOM 1067 N ARG A 142 21.765 -76.337 20.292 1.00147.26 N +ATOM 1068 CA ARG A 142 22.851 -77.247 19.988 1.00170.49 C +ATOM 1069 C ARG A 142 22.345 -78.678 20.081 1.00197.85 C +ATOM 1070 O ARG A 142 21.477 -78.987 20.900 1.00147.28 O +ATOM 1071 CB ARG A 142 24.041 -77.036 20.925 1.00175.13 C +ATOM 1072 CG ARG A 142 25.239 -77.911 20.570 1.00168.22 C +ATOM 1073 CD ARG A 142 26.552 -77.161 20.674 1.00181.96 C +ATOM 1074 NE ARG A 142 27.012 -77.103 22.057 1.00191.98 N +ATOM 1075 CZ ARG A 142 27.813 -76.163 22.555 1.00181.25 C +ATOM 1076 NH1 ARG A 142 28.279 -75.189 21.784 1.00160.38 N +ATOM 1077 NH2 ARG A 142 28.175 -76.214 23.834 1.00193.75 N +ATOM 1078 N TYR A 143 22.854 -79.525 19.188 1.00242.84 N +ATOM 1079 CA TYR A 143 22.347 -80.882 19.023 1.00231.49 C +ATOM 1080 C TYR A 143 23.503 -81.890 19.004 1.00194.86 C +ATOM 1081 O TYR A 143 23.949 -82.325 17.941 1.00168.45 O +ATOM 1082 CB TYR A 143 21.520 -80.970 17.732 1.00241.30 C +ATOM 1083 CG TYR A 143 20.835 -82.288 17.555 1.00230.57 C +ATOM 1084 CD1 TYR A 143 19.760 -82.643 18.361 1.00203.49 C +ATOM 1085 CD2 TYR A 143 21.275 -83.193 16.601 1.00227.52 C +ATOM 1086 CE1 TYR A 143 19.132 -83.863 18.217 1.00196.36 C +ATOM 1087 CE2 TYR A 143 20.651 -84.415 16.444 1.00220.50 C +ATOM 1088 CZ TYR A 143 19.584 -84.746 17.257 1.00203.78 C +ATOM 1089 OH TYR A 143 18.967 -85.966 17.115 1.00192.02 O +ATOM 1090 N GLY A 145 28.312 -82.798 17.316 1.00176.57 N +ATOM 1091 CA GLY A 145 27.465 -81.862 18.041 1.00172.94 C +ATOM 1092 C GLY A 145 27.506 -80.443 17.483 1.00181.83 C +ATOM 1093 O GLY A 145 28.523 -79.712 17.552 1.00190.54 O +ATOM 1094 N ILE A 146 26.368 -80.058 16.924 1.00183.33 N +ATOM 1095 CA ILE A 146 26.291 -78.896 16.035 1.00184.68 C +ATOM 1096 C ILE A 146 25.362 -77.849 16.650 1.00195.55 C +ATOM 1097 O ILE A 146 24.323 -78.194 17.204 1.00183.12 O +ATOM 1098 CB ILE A 146 25.765 -79.290 14.634 1.00162.31 C +ATOM 1099 CG1 ILE A 146 26.348 -80.641 14.198 1.00150.43 C +ATOM 1100 CG2 ILE A 146 26.100 -78.213 13.612 1.00145.83 C +ATOM 1101 CD1 ILE A 146 25.439 -81.822 14.473 1.00147.79 C +ATOM 1102 N GLY A 147 25.739 -76.573 16.581 1.00194.21 N +ATOM 1103 CA GLY A 147 24.942 -75.531 17.231 1.00168.96 C +ATOM 1104 C GLY A 147 24.995 -74.162 16.582 1.00155.74 C +ATOM 1105 O GLY A 147 25.975 -73.801 15.930 1.00109.90 O +ATOM 1106 N ALA A 148 23.946 -73.382 16.817 1.00155.78 N +ATOM 1107 CA ALA A 148 23.939 -71.980 16.435 1.00146.48 C +ATOM 1108 C ALA A 148 23.094 -71.157 17.409 1.00142.29 C +ATOM 1109 O ALA A 148 22.348 -71.701 18.235 1.00134.79 O +ATOM 1110 CB ALA A 148 23.425 -71.829 15.013 1.00150.63 C +ATOM 1111 N ASP A 149 23.229 -69.839 17.320 1.00143.28 N +ATOM 1112 CA ASP A 149 22.501 -68.924 18.199 1.00167.32 C +ATOM 1113 C ASP A 149 22.529 -67.527 17.651 1.00169.80 C +ATOM 1114 O ASP A 149 23.541 -67.128 17.084 1.00151.65 O +ATOM 1115 CB ASP A 149 23.193 -68.949 19.586 1.00151.59 C +ATOM 1116 CG ASP A 149 22.793 -67.807 20.525 1.00150.17 C +ATOM 1117 OD1 ASP A 149 23.314 -66.692 20.355 1.00194.11 O +ATOM 1118 OD2 ASP A 149 22.137 -68.057 21.568 1.00138.61 O +ATOM 1119 N THR A 150 21.426 -66.789 17.808 1.00152.18 N +ATOM 1120 CA THR A 150 21.496 -65.341 17.660 1.00150.27 C +ATOM 1121 C THR A 150 21.004 -64.661 18.927 1.00145.62 C +ATOM 1122 O THR A 150 20.247 -65.233 19.711 1.00109.87 O +ATOM 1123 CB THR A 150 20.676 -64.807 16.473 1.00144.64 C +ATOM 1124 OG1 THR A 150 19.301 -65.165 16.639 1.00172.07 O +ATOM 1125 CG2 THR A 150 21.199 -65.352 15.157 1.00132.61 C +ATOM 1126 N GLN A 151 21.500 -63.451 19.143 1.00129.11 N +ATOM 1127 CA GLN A 151 21.065 -62.618 20.239 1.00114.57 C +ATOM 1128 C GLN A 151 20.907 -61.213 19.718 1.00103.85 C +ATOM 1129 O GLN A 151 21.710 -60.783 18.906 1.00113.96 O +ATOM 1130 CB GLN A 151 22.104 -62.678 21.360 1.00118.52 C +ATOM 1131 CG GLN A 151 22.084 -63.995 22.116 1.00144.93 C +ATOM 1132 CD GLN A 151 23.365 -64.236 22.888 1.00169.56 C +ATOM 1133 OE1 GLN A 151 23.942 -63.309 23.446 1.00120.81 O +ATOM 1134 NE2 GLN A 151 23.838 -65.481 22.886 1.00202.21 N +ATOM 1135 N TYR A 152 19.913 -60.478 20.204 1.00 91.02 N +ATOM 1136 CA TYR A 152 19.781 -59.081 19.820 1.00 98.08 C +ATOM 1137 C TYR A 152 19.451 -58.160 20.974 1.00122.17 C +ATOM 1138 O TYR A 152 18.821 -58.571 21.952 1.00139.54 O +ATOM 1139 CB TYR A 152 18.736 -58.959 18.749 1.00102.01 C +ATOM 1140 CG TYR A 152 17.403 -58.387 19.190 1.00107.14 C +ATOM 1141 CD1 TYR A 152 16.571 -59.061 20.087 1.00 84.93 C +ATOM 1142 CD2 TYR A 152 16.904 -57.252 18.580 1.00118.27 C +ATOM 1143 CE1 TYR A 152 15.331 -58.557 20.439 1.00 72.44 C +ATOM 1144 CE2 TYR A 152 15.627 -56.789 18.859 1.00107.73 C +ATOM 1145 CZ TYR A 152 14.855 -57.435 19.802 1.00 84.65 C +ATOM 1146 OH TYR A 152 13.600 -56.948 20.089 1.00116.59 O +ATOM 1147 N GLN A 153 19.936 -56.923 20.886 1.00139.31 N +ATOM 1148 CA GLN A 153 19.543 -55.889 21.831 1.00150.05 C +ATOM 1149 C GLN A 153 19.246 -54.597 21.082 1.00134.11 C +ATOM 1150 O GLN A 153 19.777 -54.369 19.993 1.00152.29 O +ATOM 1151 CB GLN A 153 20.649 -55.666 22.871 1.00159.66 C +ATOM 1152 CG GLN A 153 20.918 -56.857 23.802 1.00157.93 C +ATOM 1153 CD GLN A 153 22.136 -56.610 24.709 1.00180.55 C +ATOM 1154 OE1 GLN A 153 22.959 -55.719 24.447 1.00196.73 O +ATOM 1155 NE2 GLN A 153 22.216 -57.346 25.815 1.00194.28 N +ATOM 1156 N LEU A 154 18.386 -53.758 21.653 1.00110.38 N +ATOM 1157 CA LEU A 154 18.165 -52.439 21.074 1.00107.54 C +ATOM 1158 C LEU A 154 17.949 -51.346 22.115 1.00116.28 C +ATOM 1159 O LEU A 154 17.312 -51.557 23.164 1.00100.98 O +ATOM 1160 CB LEU A 154 17.003 -52.468 20.084 1.00 93.56 C +ATOM 1161 CG LEU A 154 15.615 -52.617 20.707 1.00105.37 C +ATOM 1162 CD1 LEU A 154 14.937 -51.276 20.902 1.00 91.00 C +ATOM 1163 CD2 LEU A 154 14.770 -53.527 19.832 1.00146.96 C +ATOM 1164 N ASP A 155 18.411 -50.150 21.742 1.00125.98 N +ATOM 1165 CA ASP A 155 18.503 -48.980 22.623 1.00108.96 C +ATOM 1166 C ASP A 155 17.690 -47.841 22.013 1.00 89.69 C +ATOM 1167 O ASP A 155 17.380 -47.859 20.823 1.00 82.69 O +ATOM 1168 CB ASP A 155 19.968 -48.539 22.759 1.00106.99 C +ATOM 1169 CG ASP A 155 20.905 -49.703 23.033 1.00116.58 C +ATOM 1170 OD1 ASP A 155 21.254 -50.434 22.072 1.00130.83 O +ATOM 1171 OD2 ASP A 155 21.282 -49.894 24.203 1.00120.33 O +ATOM 1172 N GLN A 156 17.339 -46.854 22.824 1.00 82.69 N +ATOM 1173 CA GLN A 156 16.580 -45.711 22.323 1.00 89.46 C +ATOM 1174 C GLN A 156 17.437 -44.418 22.358 1.00 78.34 C +ATOM 1175 O GLN A 156 18.281 -44.259 23.215 1.00 67.62 O +ATOM 1176 CB GLN A 156 15.256 -45.587 23.113 1.00 79.02 C +ATOM 1177 CG GLN A 156 14.245 -44.631 22.512 1.00 82.04 C +ATOM 1178 CD GLN A 156 12.813 -44.917 22.955 1.00 98.74 C +ATOM 1179 OE1 GLN A 156 12.581 -45.718 23.851 1.00 98.54 O +ATOM 1180 NE2 GLN A 156 11.851 -44.213 22.351 1.00101.27 N +ATOM 1181 N ILE A 157 17.117 -43.469 21.491 1.00 67.43 N +ATOM 1182 CA ILE A 157 17.665 -42.126 21.578 1.00 49.66 C +ATOM 1183 C ILE A 157 16.621 -41.086 21.078 1.00 50.84 C +ATOM 1184 O ILE A 157 15.791 -41.372 20.210 1.00 50.83 O +ATOM 1185 CB ILE A 157 18.899 -42.074 20.724 1.00 50.95 C +ATOM 1186 CG1 ILE A 157 19.806 -40.945 21.188 1.00 89.21 C +ATOM 1187 CG2 ILE A 157 18.524 -41.862 19.277 1.00 57.17 C +ATOM 1188 CD1 ILE A 157 21.165 -40.936 20.517 1.00100.90 C +ATOM 1189 N ALA A 158 16.511 -39.960 21.763 1.00 50.94 N +ATOM 1190 CA ALA A 158 15.485 -38.998 21.405 1.00 50.11 C +ATOM 1191 C ALA A 158 16.114 -37.624 21.332 1.00 44.40 C +ATOM 1192 O ALA A 158 17.059 -37.303 22.059 1.00 27.64 O +ATOM 1193 CB ALA A 158 14.311 -39.024 22.393 1.00 59.59 C +ATOM 1194 N VAL A 159 15.530 -36.797 20.493 1.00 46.62 N +ATOM 1195 CA VAL A 159 16.053 -35.470 20.265 1.00 56.60 C +ATOM 1196 C VAL A 159 14.927 -34.434 20.188 1.00 70.70 C +ATOM 1197 O VAL A 159 13.914 -34.628 19.513 1.00 88.60 O +ATOM 1198 CB VAL A 159 16.854 -35.451 18.963 1.00 58.02 C +ATOM 1199 CG1 VAL A 159 16.993 -34.043 18.425 1.00 63.25 C +ATOM 1200 CG2 VAL A 159 18.203 -36.068 19.176 1.00 54.32 C +ATOM 1201 N ASN A 160 15.083 -33.373 20.955 1.00 66.48 N +ATOM 1202 CA ASN A 160 14.220 -32.237 20.846 1.00 81.55 C +ATOM 1203 C ASN A 160 14.927 -31.228 19.920 1.00 80.36 C +ATOM 1204 O ASN A 160 16.091 -30.899 20.118 1.00 73.82 O +ATOM 1205 CB ASN A 160 13.976 -31.630 22.242 1.00106.27 C +ATOM 1206 CG ASN A 160 13.102 -30.357 22.202 1.00129.66 C +ATOM 1207 OD1 ASN A 160 13.409 -29.410 21.480 1.00104.84 O +ATOM 1208 ND2 ASN A 160 12.134 -30.271 23.107 1.00134.29 N +ATOM 1209 N LEU A 161 14.194 -30.705 18.950 1.00 70.19 N +ATOM 1210 CA LEU A 161 14.562 -29.460 18.301 1.00 47.49 C +ATOM 1211 C LEU A 161 13.427 -28.482 18.427 1.00 42.84 C +ATOM 1212 O LEU A 161 12.238 -28.842 18.395 1.00 64.01 O +ATOM 1213 CB LEU A 161 14.851 -29.729 16.843 1.00 57.28 C +ATOM 1214 CG LEU A 161 16.048 -30.637 16.580 1.00 70.81 C +ATOM 1215 CD1 LEU A 161 16.110 -30.988 15.096 1.00 94.37 C +ATOM 1216 CD2 LEU A 161 17.320 -29.940 17.035 1.00 73.68 C +ATOM 1217 N ARG A 162 13.741 -27.220 18.449 1.00 44.04 N +ATOM 1218 CA ARG A 162 12.689 -26.221 18.557 1.00 64.34 C +ATOM 1219 C ARG A 162 13.053 -24.859 17.978 1.00 71.05 C +ATOM 1220 O ARG A 162 14.130 -24.307 18.274 1.00123.34 O +ATOM 1221 CB ARG A 162 12.187 -26.104 20.011 1.00 65.01 C +ATOM 1222 CG ARG A 162 13.178 -25.629 21.052 1.00 79.52 C +ATOM 1223 CD ARG A 162 12.437 -25.167 22.318 1.00 87.66 C +ATOM 1224 NE ARG A 162 13.228 -24.490 23.350 1.00 74.46 N +ATOM 1225 CZ ARG A 162 13.982 -25.146 24.230 1.00 94.06 C +ATOM 1226 NH1 ARG A 162 14.153 -26.479 24.157 1.00 95.33 N +ATOM 1227 NH2 ARG A 162 14.643 -24.459 25.134 1.00141.96 N +ATOM 1228 N VAL A 163 12.149 -24.323 17.156 1.00 59.32 N +ATOM 1229 CA VAL A 163 12.314 -22.999 16.560 1.00 69.06 C +ATOM 1230 C VAL A 163 11.833 -21.881 17.464 1.00 58.19 C +ATOM 1231 O VAL A 163 10.683 -21.882 17.877 1.00 83.52 O +ATOM 1232 CB VAL A 163 11.492 -22.857 15.282 1.00 84.79 C +ATOM 1233 CG1 VAL A 163 11.684 -21.435 14.697 1.00 88.16 C +ATOM 1234 CG2 VAL A 163 11.829 -23.969 14.287 1.00 82.65 C +ATOM 1235 N VAL A 164 12.720 -20.937 17.744 1.00 57.92 N +ATOM 1236 CA VAL A 164 12.446 -19.811 18.634 1.00 44.70 C +ATOM 1237 C VAL A 164 12.492 -18.581 17.831 1.00 41.67 C +ATOM 1238 O VAL A 164 13.426 -18.386 17.047 1.00 59.54 O +ATOM 1239 CB VAL A 164 13.510 -19.675 19.742 1.00 34.98 C +ATOM 1240 CG1 VAL A 164 13.205 -18.492 20.592 1.00 29.85 C +ATOM 1241 CG2 VAL A 164 13.509 -20.938 20.597 1.00 46.26 C +ATOM 1242 N ASN A 165 11.486 -17.763 18.013 1.00 52.91 N +ATOM 1243 CA ASN A 165 11.435 -16.475 17.331 1.00 83.76 C +ATOM 1244 C ASN A 165 12.260 -15.401 18.064 1.00 82.33 C +ATOM 1245 O ASN A 165 11.968 -15.063 19.208 1.00 59.02 O +ATOM 1246 CB ASN A 165 9.994 -15.980 17.172 1.00 75.74 C +ATOM 1247 CG ASN A 165 9.892 -14.816 16.215 1.00 80.79 C +ATOM 1248 OD1 ASN A 165 10.884 -14.420 15.592 1.00115.85 O +ATOM 1249 ND2 ASN A 165 8.775 -14.136 16.257 1.00107.46 N +ATOM 1250 N VAL A 166 13.295 -14.890 17.389 1.00 88.43 N +ATOM 1251 CA VAL A 166 14.233 -13.937 17.981 1.00 77.08 C +ATOM 1252 C VAL A 166 13.482 -12.712 18.395 1.00 61.94 C +ATOM 1253 O VAL A 166 13.759 -12.142 19.431 1.00 72.49 O +ATOM 1254 CB VAL A 166 15.350 -13.566 16.980 1.00 88.86 C +ATOM 1255 CG1 VAL A 166 15.930 -12.194 17.269 1.00 83.97 C +ATOM 1256 CG2 VAL A 166 16.429 -14.652 16.957 1.00 80.21 C +ATOM 1257 N SER A 167 12.509 -12.327 17.593 1.00 59.80 N +ATOM 1258 CA SER A 167 11.847 -11.053 17.784 1.00 83.89 C +ATOM 1259 C SER A 167 10.936 -11.045 19.009 1.00 77.29 C +ATOM 1260 O SER A 167 10.468 -9.975 19.418 1.00 80.64 O +ATOM 1261 CB SER A 167 11.068 -10.688 16.512 1.00111.63 C +ATOM 1262 OG SER A 167 11.868 -10.896 15.351 1.00153.56 O +ATOM 1263 N THR A 168 10.631 -12.226 19.550 1.00 68.93 N +ATOM 1264 CA THR A 168 9.680 -12.315 20.664 1.00 73.25 C +ATOM 1265 C THR A 168 10.110 -13.252 21.774 1.00 72.11 C +ATOM 1266 O THR A 168 9.821 -13.058 22.969 1.00 60.67 O +ATOM 1267 CB THR A 168 8.279 -12.769 20.189 1.00 70.64 C +ATOM 1268 OG1 THR A 168 8.403 -13.944 19.400 1.00 46.20 O +ATOM 1269 CG2 THR A 168 7.601 -11.657 19.372 1.00 85.39 C +ATOM 1270 N GLY A 169 10.707 -14.351 21.374 1.00 73.56 N +ATOM 1271 CA GLY A 169 11.010 -15.393 22.346 1.00 83.82 C +ATOM 1272 C GLY A 169 9.979 -16.508 22.296 1.00 50.40 C +ATOM 1273 O GLY A 169 10.160 -17.522 22.947 1.00 36.11 O +ATOM 1274 N GLU A 170 8.875 -16.252 21.613 1.00 41.84 N +ATOM 1275 CA GLU A 170 7.883 -17.275 21.406 1.00 49.74 C +ATOM 1276 C GLU A 170 8.620 -18.395 20.776 1.00 46.00 C +ATOM 1277 O GLU A 170 9.317 -18.231 19.784 1.00 61.88 O +ATOM 1278 CB GLU A 170 6.747 -16.791 20.484 1.00 69.93 C +ATOM 1279 CG GLU A 170 5.704 -15.905 21.170 1.00115.39 C +ATOM 1280 CD GLU A 170 5.154 -14.767 20.308 1.00147.11 C +ATOM 1281 OE1 GLU A 170 5.719 -14.499 19.236 1.00156.81 O +ATOM 1282 OE2 GLU A 170 4.194 -14.087 20.741 1.00173.57 O +ATOM 1283 N ILE A 171 8.455 -19.575 21.321 1.00 60.91 N +ATOM 1284 CA ILE A 171 8.813 -20.766 20.583 1.00 71.25 C +ATOM 1285 C ILE A 171 7.788 -20.967 19.455 1.00 72.20 C +ATOM 1286 O ILE A 171 6.598 -21.011 19.706 1.00 74.17 O +ATOM 1287 CB ILE A 171 8.864 -21.998 21.507 1.00 68.94 C +ATOM 1288 CG1 ILE A 171 10.062 -21.874 22.469 1.00 55.20 C +ATOM 1289 CG2 ILE A 171 8.936 -23.276 20.668 1.00 61.60 C +ATOM 1290 CD1 ILE A 171 9.967 -22.801 23.641 1.00 48.66 C +ATOM 1291 N LEU A 172 8.256 -21.057 18.212 1.00 76.72 N +ATOM 1292 CA LEU A 172 7.346 -21.205 17.073 1.00 63.95 C +ATOM 1293 C LEU A 172 7.031 -22.675 16.747 1.00 55.51 C +ATOM 1294 O LEU A 172 6.187 -22.978 15.906 1.00 53.80 O +ATOM 1295 CB LEU A 172 7.890 -20.454 15.836 1.00 72.58 C +ATOM 1296 CG LEU A 172 7.557 -18.965 15.626 1.00 92.22 C +ATOM 1297 CD1 LEU A 172 7.278 -18.362 16.985 1.00100.35 C +ATOM 1298 CD2 LEU A 172 8.521 -18.111 14.808 1.00102.34 C +ATOM 1299 N SER A 173 7.827 -23.573 17.307 1.00 65.10 N +ATOM 1300 CA SER A 173 7.719 -24.978 17.004 1.00 71.31 C +ATOM 1301 C SER A 173 8.616 -25.798 17.922 1.00 67.65 C +ATOM 1302 O SER A 173 9.807 -25.566 18.015 1.00 57.34 O +ATOM 1303 CB SER A 173 8.096 -25.286 15.541 1.00 83.15 C +ATOM 1304 OG SER A 173 8.258 -26.690 15.356 1.00125.88 O +ATOM 1305 N SER A 174 8.039 -26.821 18.544 1.00 86.05 N +ATOM 1306 CA SER A 174 8.815 -27.862 19.222 1.00 78.17 C +ATOM 1307 C SER A 174 8.496 -29.227 18.618 1.00 74.52 C +ATOM 1308 O SER A 174 7.341 -29.546 18.376 1.00 51.67 O +ATOM 1309 CB SER A 174 8.516 -27.876 20.733 1.00 77.44 C +ATOM 1310 OG SER A 174 9.439 -28.680 21.464 1.00 50.25 O +ATOM 1311 N VAL A 175 9.540 -30.030 18.404 1.00 84.58 N +ATOM 1312 CA VAL A 175 9.385 -31.397 17.876 1.00 79.90 C +ATOM 1313 C VAL A 175 10.268 -32.407 18.592 1.00 58.92 C +ATOM 1314 O VAL A 175 11.389 -32.065 19.030 1.00 66.50 O +ATOM 1315 CB VAL A 175 9.712 -31.441 16.381 1.00 94.94 C +ATOM 1316 CG1 VAL A 175 8.751 -30.568 15.593 1.00108.14 C +ATOM 1317 CG2 VAL A 175 11.133 -30.974 16.113 1.00 98.62 C +ATOM 1318 N ASN A 176 9.757 -33.619 18.734 1.00 48.63 N +ATOM 1319 CA ASN A 176 10.408 -34.637 19.590 1.00 57.90 C +ATOM 1320 C ASN A 176 10.645 -35.980 18.904 1.00 48.62 C +ATOM 1321 O ASN A 176 9.741 -36.794 18.859 1.00 41.62 O +ATOM 1322 CB ASN A 176 9.551 -34.868 20.850 1.00 62.17 C +ATOM 1323 CG ASN A 176 10.068 -34.081 22.047 1.00 89.31 C +ATOM 1324 OD1 ASN A 176 10.859 -33.154 21.864 1.00 79.52 O +ATOM 1325 ND2 ASN A 176 9.624 -34.417 23.280 1.00124.01 N +ATOM 1326 N THR A 177 11.812 -36.161 18.300 1.00 50.43 N +ATOM 1327 CA THR A 177 12.033 -37.323 17.461 1.00 59.48 C +ATOM 1328 C THR A 177 12.756 -38.370 18.245 1.00 71.04 C +ATOM 1329 O THR A 177 13.381 -38.085 19.262 1.00 60.21 O +ATOM 1330 CB THR A 177 12.851 -36.997 16.190 1.00 72.44 C +ATOM 1331 OG1 THR A 177 14.188 -36.635 16.545 1.00 48.49 O +ATOM 1332 CG2 THR A 177 12.214 -35.832 15.383 1.00 80.97 C +ATOM 1333 N SER A 178 12.654 -39.600 17.766 1.00 87.75 N +ATOM 1334 CA SER A 178 13.212 -40.744 18.479 1.00 82.02 C +ATOM 1335 C SER A 178 13.683 -41.789 17.503 1.00 68.74 C +ATOM 1336 O SER A 178 13.181 -41.905 16.376 1.00 78.12 O +ATOM 1337 CB SER A 178 12.175 -41.365 19.417 1.00 91.71 C +ATOM 1338 OG SER A 178 12.580 -42.650 19.858 1.00 74.66 O +ATOM 1339 N LYS A 179 14.644 -42.573 17.938 1.00 63.56 N +ATOM 1340 CA LYS A 179 15.263 -43.520 17.032 1.00 78.03 C +ATOM 1341 C LYS A 179 15.865 -44.682 17.818 1.00 78.61 C +ATOM 1342 O LYS A 179 16.356 -44.518 18.941 1.00 58.34 O +ATOM 1343 CB LYS A 179 16.333 -42.807 16.200 1.00 78.57 C +ATOM 1344 CG LYS A 179 16.461 -43.303 14.777 1.00 83.59 C +ATOM 1345 CD LYS A 179 17.533 -44.370 14.686 1.00 95.27 C +ATOM 1346 CE LYS A 179 17.547 -44.989 13.307 1.00114.23 C +ATOM 1347 NZ LYS A 179 18.370 -46.221 13.268 1.00130.65 N +ATOM 1348 N THR A 180 15.809 -45.861 17.218 1.00 84.35 N +ATOM 1349 CA THR A 180 16.229 -47.066 17.898 1.00 86.42 C +ATOM 1350 C THR A 180 17.559 -47.561 17.320 1.00 84.85 C +ATOM 1351 O THR A 180 17.739 -47.660 16.100 1.00 84.03 O +ATOM 1352 CB THR A 180 15.144 -48.167 17.842 1.00 83.21 C +ATOM 1353 OG1 THR A 180 15.760 -49.453 17.980 1.00 87.70 O +ATOM 1354 CG2 THR A 180 14.365 -48.108 16.529 1.00 78.36 C +ATOM 1355 N ILE A 181 18.473 -47.906 18.214 1.00 86.46 N +ATOM 1356 CA ILE A 181 19.766 -48.439 17.817 1.00 94.83 C +ATOM 1357 C ILE A 181 19.775 -49.975 17.944 1.00 88.20 C +ATOM 1358 O ILE A 181 19.652 -50.514 19.051 1.00 95.60 O +ATOM 1359 CB ILE A 181 20.906 -47.812 18.667 1.00115.66 C +ATOM 1360 CG1 ILE A 181 20.824 -46.283 18.639 1.00105.07 C +ATOM 1361 CG2 ILE A 181 22.286 -48.242 18.173 1.00135.47 C +ATOM 1362 CD1 ILE A 181 20.612 -45.661 19.999 1.00104.48 C +ATOM 1363 N LEU A 182 19.999 -50.656 16.819 1.00 73.60 N +ATOM 1364 CA LEU A 182 19.992 -52.112 16.767 1.00 77.02 C +ATOM 1365 C LEU A 182 21.364 -52.748 16.930 1.00 87.45 C +ATOM 1366 O LEU A 182 22.356 -52.310 16.335 1.00 81.91 O +ATOM 1367 CB LEU A 182 19.402 -52.575 15.441 1.00 94.00 C +ATOM 1368 CG LEU A 182 19.327 -54.091 15.231 1.00 89.81 C +ATOM 1369 CD1 LEU A 182 18.442 -54.795 16.260 1.00 72.51 C +ATOM 1370 CD2 LEU A 182 18.842 -54.353 13.811 1.00 99.99 C +ATOM 1371 N SER A 183 21.397 -53.844 17.689 1.00127.25 N +ATOM 1372 CA SER A 183 22.602 -54.667 17.832 1.00139.54 C +ATOM 1373 C SER A 183 22.248 -56.159 17.804 1.00128.96 C +ATOM 1374 O SER A 183 21.217 -56.570 18.347 1.00114.90 O +ATOM 1375 CB SER A 183 23.303 -54.331 19.145 1.00137.87 C +ATOM 1376 OG SER A 183 23.223 -52.939 19.420 1.00140.67 O +ATOM 1377 N TYR A 184 23.085 -56.958 17.147 1.00110.33 N +ATOM 1378 CA TYR A 184 22.869 -58.397 17.115 1.00114.92 C +ATOM 1379 C TYR A 184 24.150 -59.221 16.960 1.00139.00 C +ATOM 1380 O TYR A 184 25.170 -58.752 16.443 1.00138.19 O +ATOM 1381 CB TYR A 184 21.866 -58.767 16.030 1.00100.32 C +ATOM 1382 CG TYR A 184 22.289 -58.327 14.650 1.00100.70 C +ATOM 1383 CD1 TYR A 184 22.058 -57.028 14.183 1.00125.76 C +ATOM 1384 CD2 TYR A 184 22.888 -59.218 13.796 1.00 94.98 C +ATOM 1385 CE1 TYR A 184 22.452 -56.642 12.906 1.00131.92 C +ATOM 1386 CE2 TYR A 184 23.274 -58.847 12.521 1.00100.46 C +ATOM 1387 CZ TYR A 184 23.063 -57.562 12.078 1.00 99.88 C +ATOM 1388 OH TYR A 184 23.397 -57.212 10.786 1.00 69.46 O +ATOM 1389 N GLU A 185 24.073 -60.459 17.448 1.00160.73 N +ATOM 1390 CA GLU A 185 25.200 -61.392 17.467 1.00162.08 C +ATOM 1391 C GLU A 185 24.771 -62.750 16.954 1.00164.00 C +ATOM 1392 O GLU A 185 24.001 -63.448 17.608 1.00167.80 O +ATOM 1393 CB GLU A 185 25.795 -61.584 18.868 1.00163.93 C +ATOM 1394 CG GLU A 185 25.942 -60.333 19.705 1.00180.61 C +ATOM 1395 CD GLU A 185 26.723 -60.609 20.978 1.00179.47 C +ATOM 1396 OE1 GLU A 185 27.103 -61.782 21.206 1.00124.98 O +ATOM 1397 OE2 GLU A 185 26.989 -59.646 21.727 1.00208.24 O +ATOM 1398 N VAL A 186 25.298 -63.121 15.794 1.00154.11 N +ATOM 1399 CA VAL A 186 25.051 -64.420 15.204 1.00141.39 C +ATOM 1400 C VAL A 186 26.263 -65.322 15.419 1.00154.13 C +ATOM 1401 O VAL A 186 27.406 -64.881 15.302 1.00148.65 O +ATOM 1402 CB VAL A 186 24.767 -64.288 13.700 1.00143.64 C +ATOM 1403 CG1 VAL A 186 24.309 -65.622 13.133 1.00167.12 C +ATOM 1404 CG2 VAL A 186 23.715 -63.216 13.447 1.00142.31 C +ATOM 1405 N GLN A 187 26.006 -66.581 15.760 1.00181.03 N +ATOM 1406 CA GLN A 187 27.082 -67.519 16.068 1.00194.25 C +ATOM 1407 C GLN A 187 26.715 -68.934 15.661 1.00215.07 C +ATOM 1408 O GLN A 187 25.594 -69.377 15.903 1.00198.71 O +ATOM 1409 CB GLN A 187 27.369 -67.500 17.573 1.00175.77 C +ATOM 1410 CG GLN A 187 28.336 -66.431 18.036 1.00172.13 C +ATOM 1411 CD GLN A 187 28.189 -66.139 19.516 1.00168.40 C +ATOM 1412 OE1 GLN A 187 27.975 -67.052 20.316 1.00145.40 O +ATOM 1413 NE2 GLN A 187 28.276 -64.857 19.889 1.00165.56 N +ATOM 1414 N ALA A 188 27.678 -69.644 15.075 1.00203.11 N +ATOM 1415 CA ALA A 188 27.482 -71.047 14.731 1.00150.43 C +ATOM 1416 C ALA A 188 28.766 -71.831 14.976 1.00162.90 C +ATOM 1417 O ALA A 188 29.865 -71.345 14.709 1.00177.81 O +ATOM 1418 CB ALA A 188 27.039 -71.177 13.287 1.00125.29 C +ATOM 1419 N GLY A 189 28.630 -73.033 15.514 1.00171.87 N +ATOM 1420 CA GLY A 189 29.782 -73.882 15.791 1.00192.84 C +ATOM 1421 C GLY A 189 29.502 -75.359 15.571 1.00201.50 C +ATOM 1422 O GLY A 189 28.441 -75.854 15.946 1.00201.79 O +ATOM 1423 N VAL A 190 30.468 -76.060 14.978 1.00188.15 N +ATOM 1424 CA VAL A 190 30.383 -77.500 14.795 1.00161.79 C +ATOM 1425 C VAL A 190 31.465 -78.206 15.632 1.00181.38 C +ATOM 1426 O VAL A 190 32.628 -77.787 15.664 1.00152.95 O +ATOM 1427 CB VAL A 190 30.537 -77.878 13.315 1.00134.60 C +ATOM 1428 CG1 VAL A 190 30.177 -79.342 13.110 1.00135.93 C +ATOM 1429 CG2 VAL A 190 29.679 -76.974 12.441 1.00115.41 C +ATOM 1430 N PHE A 191 31.073 -79.266 16.332 1.00199.11 N +ATOM 1431 CA PHE A 191 31.950 -79.911 17.312 1.00192.62 C +ATOM 1432 C PHE A 191 31.920 -81.418 17.143 1.00201.16 C +ATOM 1433 O PHE A 191 30.849 -82.033 17.017 1.00243.63 O +ATOM 1434 CB PHE A 191 31.514 -79.551 18.736 1.00175.28 C +ATOM 1435 CG PHE A 191 32.589 -79.744 19.772 1.00185.39 C +ATOM 1436 CD1 PHE A 191 32.967 -81.018 20.177 1.00173.05 C +ATOM 1437 CD2 PHE A 191 33.219 -78.649 20.349 1.00195.77 C +ATOM 1438 CE1 PHE A 191 33.952 -81.198 21.135 1.00148.41 C +ATOM 1439 CE2 PHE A 191 34.195 -78.822 21.316 1.00182.03 C +ATOM 1440 CZ PHE A 191 34.563 -80.100 21.708 1.00159.74 C +ATOM 1441 N ARG A 192 33.100 -82.025 17.156 1.00183.55 N +ATOM 1442 CA ARG A 192 33.203 -83.441 16.854 1.00169.56 C +ATOM 1443 C ARG A 192 34.554 -84.032 17.203 1.00137.81 C +ATOM 1444 O ARG A 192 34.743 -85.240 17.065 1.00137.54 O +ATOM 1445 CB ARG A 192 32.906 -83.701 15.369 1.00161.07 C +ATOM 1446 CG ARG A 192 31.613 -84.459 15.108 1.00156.81 C +ATOM 1447 CD ARG A 192 30.932 -84.071 13.798 1.00137.18 C +ATOM 1448 NE ARG A 192 29.493 -84.258 13.947 1.00154.04 N +ATOM 1449 CZ ARG A 192 28.806 -85.332 13.559 1.00152.96 C +ATOM 1450 NH1 ARG A 192 29.383 -86.309 12.871 1.00153.81 N +ATOM 1451 NH2 ARG A 192 27.511 -85.403 13.829 1.00150.58 N +ATOM 1452 N LEU A 200 37.478 -82.566 15.952 1.00125.30 N +ATOM 1453 CA LEU A 200 37.013 -81.499 15.067 1.00138.73 C +ATOM 1454 C LEU A 200 36.177 -80.464 15.823 1.00186.32 C +ATOM 1455 O LEU A 200 35.062 -80.757 16.275 1.00181.23 O +ATOM 1456 CB LEU A 200 36.175 -82.061 13.915 1.00111.39 C +ATOM 1457 CG LEU A 200 35.485 -80.993 13.044 1.00128.14 C +ATOM 1458 CD1 LEU A 200 36.255 -80.770 11.750 1.00114.82 C +ATOM 1459 CD2 LEU A 200 34.014 -81.311 12.765 1.00144.52 C +ATOM 1460 N GLU A 201 36.698 -79.239 15.907 1.00218.25 N +ATOM 1461 CA GLU A 201 35.883 -78.065 16.221 1.00196.23 C +ATOM 1462 C GLU A 201 35.965 -77.036 15.095 1.00172.24 C +ATOM 1463 O GLU A 201 36.987 -76.924 14.425 1.00177.50 O +ATOM 1464 CB GLU A 201 36.339 -77.426 17.530 1.00184.46 C +ATOM 1465 CG GLU A 201 35.279 -76.528 18.145 1.00200.81 C +ATOM 1466 CD GLU A 201 35.721 -75.886 19.448 1.00210.46 C +ATOM 1467 OE1 GLU A 201 36.202 -76.611 20.345 1.00221.47 O +ATOM 1468 OE2 GLU A 201 35.569 -74.653 19.584 1.00216.96 O +ATOM 1469 N GLY A 202 34.871 -76.317 14.869 1.00151.55 N +ATOM 1470 CA GLY A 202 34.856 -75.211 13.924 1.00172.16 C +ATOM 1471 C GLY A 202 33.803 -74.183 14.296 1.00217.08 C +ATOM 1472 O GLY A 202 32.629 -74.520 14.469 1.00276.09 O +ATOM 1473 N GLU A 203 34.217 -72.924 14.429 1.00208.37 N +ATOM 1474 CA GLU A 203 33.307 -71.864 14.863 1.00167.82 C +ATOM 1475 C GLU A 203 33.343 -70.625 13.967 1.00174.65 C +ATOM 1476 O GLU A 203 34.415 -70.143 13.585 1.00136.89 O +ATOM 1477 CB GLU A 203 33.614 -71.459 16.303 1.00154.23 C +ATOM 1478 CG GLU A 203 33.318 -72.562 17.314 1.00159.57 C +ATOM 1479 CD GLU A 203 33.528 -72.151 18.766 1.00181.70 C +ATOM 1480 OE1 GLU A 203 34.037 -71.034 19.008 1.00176.37 O +ATOM 1481 OE2 GLU A 203 33.199 -72.962 19.667 1.00209.94 O +ATOM 1482 N VAL A 204 32.153 -70.107 13.672 1.00184.00 N +ATOM 1483 CA VAL A 204 31.989 -68.811 13.023 1.00145.83 C +ATOM 1484 C VAL A 204 31.121 -67.920 13.916 1.00132.50 C +ATOM 1485 O VAL A 204 30.106 -68.357 14.469 1.00122.02 O +ATOM 1486 CB VAL A 204 31.350 -68.966 11.628 1.00126.22 C +ATOM 1487 CG1 VAL A 204 30.841 -67.632 11.096 1.00124.41 C +ATOM 1488 CG2 VAL A 204 32.357 -69.578 10.669 1.00120.22 C +ATOM 1489 N GLY A 205 31.546 -66.674 14.064 1.00126.89 N +ATOM 1490 CA GLY A 205 30.782 -65.686 14.807 1.00139.74 C +ATOM 1491 C GLY A 205 30.760 -64.344 14.092 1.00165.32 C +ATOM 1492 O GLY A 205 31.712 -63.986 13.385 1.00226.61 O +ATOM 1493 N TYR A 206 29.669 -63.605 14.264 1.00145.06 N +ATOM 1494 CA TYR A 206 29.549 -62.256 13.712 1.00119.48 C +ATOM 1495 C TYR A 206 28.687 -61.389 14.615 1.00129.98 C +ATOM 1496 O TYR A 206 27.711 -61.861 15.172 1.00115.68 O +ATOM 1497 CB TYR A 206 28.927 -62.298 12.322 1.00103.72 C +ATOM 1498 CG TYR A 206 28.716 -60.936 11.704 1.00107.58 C +ATOM 1499 CD1 TYR A 206 29.786 -60.206 11.168 1.00106.06 C +ATOM 1500 CD2 TYR A 206 27.446 -60.377 11.641 1.00119.14 C +ATOM 1501 CE1 TYR A 206 29.599 -58.955 10.595 1.00108.56 C +ATOM 1502 CE2 TYR A 206 27.247 -59.135 11.060 1.00117.34 C +ATOM 1503 CZ TYR A 206 28.316 -58.426 10.535 1.00120.79 C +ATOM 1504 OH TYR A 206 28.090 -57.190 9.963 1.00106.99 O +ATOM 1505 N THR A 207 29.072 -60.127 14.784 1.00154.81 N +ATOM 1506 CA THR A 207 28.311 -59.193 15.616 1.00142.58 C +ATOM 1507 C THR A 207 28.220 -57.825 14.945 1.00128.64 C +ATOM 1508 O THR A 207 29.213 -57.317 14.393 1.00108.83 O +ATOM 1509 CB THR A 207 28.941 -59.010 17.013 1.00145.53 C +ATOM 1510 OG1 THR A 207 30.256 -58.460 16.883 1.00147.10 O +ATOM 1511 CG2 THR A 207 29.041 -60.335 17.741 1.00160.45 C +ATOM 1512 N SER A 208 27.025 -57.243 14.970 1.00118.24 N +ATOM 1513 CA SER A 208 26.829 -55.940 14.337 1.00130.66 C +ATOM 1514 C SER A 208 26.071 -54.974 15.232 1.00135.55 C +ATOM 1515 O SER A 208 24.981 -55.289 15.714 1.00105.11 O +ATOM 1516 CB SER A 208 26.106 -56.077 12.995 1.00138.83 C +ATOM 1517 OG SER A 208 25.787 -54.789 12.467 1.00129.44 O +ATOM 1518 N ASN A 209 26.672 -53.799 15.441 1.00141.49 N +ATOM 1519 CA ASN A 209 26.043 -52.689 16.159 1.00106.21 C +ATOM 1520 C ASN A 209 25.781 -51.552 15.204 1.00 97.33 C +ATOM 1521 O ASN A 209 26.636 -51.199 14.395 1.00 90.58 O +ATOM 1522 CB ASN A 209 26.949 -52.174 17.264 1.00 86.73 C +ATOM 1523 CG ASN A 209 27.087 -53.153 18.395 1.00102.59 C +ATOM 1524 OD1 ASN A 209 26.239 -53.226 19.278 1.00133.46 O +ATOM 1525 ND2 ASN A 209 28.175 -53.912 18.385 1.00101.10 N +ATOM 1526 N GLU A 210 24.600 -50.972 15.308 1.00 89.08 N +ATOM 1527 CA GLU A 210 24.360 -49.708 14.657 1.00 84.52 C +ATOM 1528 C GLU A 210 25.248 -48.658 15.323 1.00 84.25 C +ATOM 1529 O GLU A 210 25.428 -48.650 16.542 1.00104.84 O +ATOM 1530 CB GLU A 210 22.885 -49.320 14.786 1.00 98.33 C +ATOM 1531 CG GLU A 210 22.247 -48.780 13.516 1.00124.35 C +ATOM 1532 CD GLU A 210 20.713 -48.828 13.552 1.00123.92 C +ATOM 1533 OE1 GLU A 210 20.122 -49.660 14.282 1.00 76.37 O +ATOM 1534 OE2 GLU A 210 20.104 -47.999 12.851 1.00119.21 O +ATOM 1535 N PRO A 211 25.817 -47.757 14.529 1.00 66.75 N +ATOM 1536 CA PRO A 211 26.453 -46.602 15.132 1.00 66.75 C +ATOM 1537 C PRO A 211 25.461 -45.622 15.790 1.00 55.20 C +ATOM 1538 O PRO A 211 24.549 -45.130 15.120 1.00 62.75 O +ATOM 1539 CB PRO A 211 27.187 -45.944 13.939 1.00 64.70 C +ATOM 1540 CG PRO A 211 27.233 -46.984 12.882 1.00 59.64 C +ATOM 1541 CD PRO A 211 25.962 -47.749 13.074 1.00 66.93 C +ATOM 1542 N VAL A 212 25.660 -45.352 17.078 1.00 48.90 N +ATOM 1543 CA VAL A 212 24.861 -44.375 17.793 1.00 62.22 C +ATOM 1544 C VAL A 212 25.025 -42.984 17.164 1.00 78.01 C +ATOM 1545 O VAL A 212 24.050 -42.239 16.992 1.00113.75 O +ATOM 1546 CB VAL A 212 25.266 -44.286 19.278 1.00 71.26 C +ATOM 1547 CG1 VAL A 212 24.308 -43.387 20.062 1.00 61.26 C +ATOM 1548 CG2 VAL A 212 25.334 -45.674 19.914 1.00 79.21 C +ATOM 1549 N MET A 213 26.270 -42.636 16.884 1.00 89.95 N +ATOM 1550 CA MET A 213 26.642 -41.567 15.968 1.00102.63 C +ATOM 1551 C MET A 213 25.660 -41.335 14.799 1.00100.95 C +ATOM 1552 O MET A 213 25.165 -40.215 14.559 1.00 95.03 O +ATOM 1553 CB MET A 213 28.007 -41.982 15.414 1.00122.74 C +ATOM 1554 CG MET A 213 28.725 -41.001 14.531 1.00122.88 C +ATOM 1555 SD MET A 213 30.275 -41.780 14.057 1.00125.09 S +ATOM 1556 CE MET A 213 29.913 -42.003 12.337 1.00125.53 C +ATOM 1557 N LEU A 214 25.361 -42.416 14.089 1.00 93.64 N +ATOM 1558 CA LEU A 214 24.645 -42.345 12.816 1.00114.95 C +ATOM 1559 C LEU A 214 23.131 -42.267 13.053 1.00105.53 C +ATOM 1560 O LEU A 214 22.397 -41.663 12.275 1.00 81.76 O +ATOM 1561 CB LEU A 214 24.983 -43.577 11.961 1.00128.96 C +ATOM 1562 CG LEU A 214 25.287 -43.402 10.467 1.00124.29 C +ATOM 1563 CD1 LEU A 214 26.474 -42.480 10.222 1.00109.49 C +ATOM 1564 CD2 LEU A 214 25.537 -44.766 9.831 1.00115.74 C +ATOM 1565 N CYS A 215 22.688 -42.837 14.168 1.00111.49 N +ATOM 1566 CA CYS A 215 21.286 -42.755 14.594 1.00112.04 C +ATOM 1567 C CYS A 215 20.916 -41.366 15.116 1.00 94.24 C +ATOM 1568 O CYS A 215 19.843 -40.814 14.785 1.00 98.62 O +ATOM 1569 CB CYS A 215 21.013 -43.738 15.724 1.00109.06 C +ATOM 1570 SG CYS A 215 21.198 -45.451 15.241 1.00 89.11 S +ATOM 1571 N LEU A 216 21.819 -40.802 15.905 1.00 59.68 N +ATOM 1572 CA LEU A 216 21.703 -39.414 16.265 1.00 71.74 C +ATOM 1573 C LEU A 216 21.535 -38.531 15.009 1.00 81.80 C +ATOM 1574 O LEU A 216 20.628 -37.678 14.948 1.00 88.96 O +ATOM 1575 CB LEU A 216 22.927 -38.945 17.078 1.00 71.07 C +ATOM 1576 CG LEU A 216 22.916 -37.479 17.545 1.00 58.74 C +ATOM 1577 CD1 LEU A 216 21.686 -37.145 18.370 1.00 69.01 C +ATOM 1578 CD2 LEU A 216 24.149 -37.160 18.333 1.00 48.64 C +ATOM 1579 N MET A 217 22.424 -38.707 14.029 1.00 76.28 N +ATOM 1580 CA MET A 217 22.416 -37.856 12.847 1.00 82.30 C +ATOM 1581 C MET A 217 21.090 -37.998 12.105 1.00 75.15 C +ATOM 1582 O MET A 217 20.460 -37.011 11.744 1.00 81.98 O +ATOM 1583 CB MET A 217 23.580 -38.193 11.931 1.00107.42 C +ATOM 1584 CG MET A 217 24.292 -36.965 11.357 1.00136.10 C +ATOM 1585 SD MET A 217 23.278 -36.075 10.154 1.00161.53 S +ATOM 1586 CE MET A 217 24.221 -34.573 9.889 1.00146.43 C +ATOM 1587 N SER A 218 20.644 -39.233 11.940 1.00 82.08 N +ATOM 1588 CA SER A 218 19.377 -39.532 11.264 1.00 86.14 C +ATOM 1589 C SER A 218 18.234 -38.814 11.937 1.00 69.69 C +ATOM 1590 O SER A 218 17.415 -38.180 11.278 1.00 72.50 O +ATOM 1591 CB SER A 218 19.124 -41.055 11.273 1.00111.35 C +ATOM 1592 OG SER A 218 18.039 -41.417 10.451 1.00 82.90 O +ATOM 1593 N ALA A 219 18.163 -38.951 13.255 1.00 67.28 N +ATOM 1594 CA ALA A 219 17.039 -38.419 14.012 1.00 83.86 C +ATOM 1595 C ALA A 219 16.993 -36.887 13.958 1.00 64.05 C +ATOM 1596 O ALA A 219 15.922 -36.276 13.903 1.00 61.42 O +ATOM 1597 CB ALA A 219 17.110 -38.910 15.453 1.00108.92 C +ATOM 1598 N ILE A 220 18.160 -36.271 13.933 1.00 65.59 N +ATOM 1599 CA ILE A 220 18.228 -34.819 13.814 1.00 77.82 C +ATOM 1600 C ILE A 220 17.734 -34.337 12.439 1.00 88.11 C +ATOM 1601 O ILE A 220 16.993 -33.363 12.343 1.00 83.92 O +ATOM 1602 CB ILE A 220 19.660 -34.308 14.059 1.00 80.98 C +ATOM 1603 CG1 ILE A 220 20.036 -34.513 15.540 1.00 69.51 C +ATOM 1604 CG2 ILE A 220 19.797 -32.842 13.635 1.00 70.69 C +ATOM 1605 CD1 ILE A 220 21.526 -34.417 15.818 1.00 80.14 C +ATOM 1606 N GLU A 221 18.111 -35.047 11.379 1.00105.23 N +ATOM 1607 CA GLU A 221 17.585 -34.764 10.034 1.00106.74 C +ATOM 1608 C GLU A 221 16.040 -34.817 10.001 1.00 79.12 C +ATOM 1609 O GLU A 221 15.389 -33.873 9.563 1.00 55.01 O +ATOM 1610 CB GLU A 221 18.162 -35.766 9.017 1.00128.93 C +ATOM 1611 CG GLU A 221 19.629 -35.528 8.693 1.00142.17 C +ATOM 1612 CD GLU A 221 20.308 -36.718 8.031 1.00139.06 C +ATOM 1613 OE1 GLU A 221 19.998 -37.891 8.376 1.00 94.64 O +ATOM 1614 OE2 GLU A 221 21.182 -36.452 7.171 1.00139.79 O +ATOM 1615 N THR A 222 15.489 -35.926 10.502 1.00 57.38 N +ATOM 1616 CA THR A 222 14.049 -36.141 10.632 1.00 42.69 C +ATOM 1617 C THR A 222 13.383 -34.998 11.355 1.00 41.09 C +ATOM 1618 O THR A 222 12.389 -34.451 10.878 1.00 45.75 O +ATOM 1619 CB THR A 222 13.773 -37.425 11.431 1.00 44.03 C +ATOM 1620 OG1 THR A 222 14.122 -38.587 10.640 1.00 45.35 O +ATOM 1621 CG2 THR A 222 12.322 -37.484 11.899 1.00 45.62 C +ATOM 1622 N GLY A 223 13.961 -34.607 12.479 1.00 48.85 N +ATOM 1623 CA GLY A 223 13.508 -33.432 13.205 1.00 71.85 C +ATOM 1624 C GLY A 223 13.468 -32.149 12.363 1.00 84.68 C +ATOM 1625 O GLY A 223 12.523 -31.347 12.468 1.00 70.74 O +ATOM 1626 N VAL A 224 14.496 -31.944 11.546 1.00 82.09 N +ATOM 1627 CA VAL A 224 14.567 -30.749 10.729 1.00 79.26 C +ATOM 1628 C VAL A 224 13.412 -30.756 9.727 1.00 73.63 C +ATOM 1629 O VAL A 224 12.779 -29.728 9.487 1.00 73.00 O +ATOM 1630 CB VAL A 224 15.900 -30.649 9.979 1.00 81.10 C +ATOM 1631 CG1 VAL A 224 15.864 -29.502 8.978 1.00 85.71 C +ATOM 1632 CG2 VAL A 224 17.046 -30.467 10.951 1.00 74.67 C +ATOM 1633 N ILE A 225 13.133 -31.915 9.153 1.00 64.18 N +ATOM 1634 CA ILE A 225 12.031 -32.025 8.212 1.00 78.18 C +ATOM 1635 C ILE A 225 10.729 -31.635 8.914 1.00 81.25 C +ATOM 1636 O ILE A 225 9.970 -30.826 8.375 1.00 65.06 O +ATOM 1637 CB ILE A 225 11.921 -33.446 7.588 1.00 87.16 C +ATOM 1638 CG1 ILE A 225 13.112 -33.702 6.668 1.00 85.76 C +ATOM 1639 CG2 ILE A 225 10.644 -33.590 6.782 1.00 82.52 C +ATOM 1640 CD1 ILE A 225 13.336 -35.170 6.364 1.00 93.62 C +ATOM 1641 N PHE A 226 10.444 -32.261 10.069 1.00 86.41 N +ATOM 1642 CA PHE A 226 9.184 -32.014 10.814 1.00 80.44 C +ATOM 1643 C PHE A 226 9.071 -30.536 11.149 1.00 79.87 C +ATOM 1644 O PHE A 226 7.977 -29.990 11.175 1.00 81.74 O +ATOM 1645 CB PHE A 226 9.110 -32.837 12.112 1.00 73.77 C +ATOM 1646 CG PHE A 226 8.658 -34.264 11.932 1.00 91.79 C +ATOM 1647 CD1 PHE A 226 7.442 -34.555 11.318 1.00 97.23 C +ATOM 1648 CD2 PHE A 226 9.425 -35.325 12.422 1.00 84.46 C +ATOM 1649 CE1 PHE A 226 7.024 -35.872 11.146 1.00 81.46 C +ATOM 1650 CE2 PHE A 226 9.002 -36.634 12.246 1.00 78.67 C +ATOM 1651 CZ PHE A 226 7.810 -36.904 11.594 1.00 70.47 C +ATOM 1652 N LEU A 227 10.210 -29.886 11.378 1.00 92.27 N +ATOM 1653 CA LEU A 227 10.230 -28.447 11.655 1.00 81.28 C +ATOM 1654 C LEU A 227 9.813 -27.653 10.421 1.00 68.14 C +ATOM 1655 O LEU A 227 9.041 -26.727 10.530 1.00 59.06 O +ATOM 1656 CB LEU A 227 11.619 -28.040 12.141 1.00 67.12 C +ATOM 1657 CG LEU A 227 11.970 -28.406 13.582 1.00 67.63 C +ATOM 1658 CD1 LEU A 227 13.433 -28.272 13.953 1.00 77.03 C +ATOM 1659 CD2 LEU A 227 11.139 -27.589 14.553 1.00 86.35 C +ATOM 1660 N ILE A 228 10.340 -28.020 9.260 1.00 63.49 N +ATOM 1661 CA ILE A 228 10.056 -27.289 8.051 1.00 67.30 C +ATOM 1662 C ILE A 228 8.590 -27.449 7.744 1.00 65.75 C +ATOM 1663 O ILE A 228 7.897 -26.498 7.372 1.00 51.49 O +ATOM 1664 CB ILE A 228 10.903 -27.777 6.856 1.00 90.51 C +ATOM 1665 CG1 ILE A 228 12.388 -27.489 7.092 1.00 95.63 C +ATOM 1666 CG2 ILE A 228 10.480 -27.078 5.566 1.00 98.85 C +ATOM 1667 CD1 ILE A 228 13.328 -28.239 6.163 1.00112.64 C +ATOM 1668 N ASN A 229 8.132 -28.689 7.775 1.00 79.94 N +ATOM 1669 CA ASN A 229 6.740 -28.996 7.408 1.00 97.11 C +ATOM 1670 C ASN A 229 5.820 -28.221 8.347 1.00 75.80 C +ATOM 1671 O ASN A 229 4.799 -27.680 7.920 1.00117.74 O +ATOM 1672 CB ASN A 229 6.494 -30.525 7.496 1.00101.75 C +ATOM 1673 CG ASN A 229 5.212 -30.969 6.822 1.00 79.67 C +ATOM 1674 OD1 ASN A 229 4.693 -30.306 5.910 1.00 98.66 O +ATOM 1675 ND2 ASN A 229 4.700 -32.114 7.258 1.00 67.85 N +ATOM 1676 N ASP A 230 6.180 -28.196 9.625 1.00 55.86 N +ATOM 1677 CA ASP A 230 5.368 -27.543 10.631 1.00 60.69 C +ATOM 1678 C ASP A 230 5.321 -26.053 10.347 1.00 52.63 C +ATOM 1679 O ASP A 230 4.279 -25.418 10.489 1.00 50.84 O +ATOM 1680 CB ASP A 230 5.952 -27.802 12.029 1.00 80.07 C +ATOM 1681 CG ASP A 230 5.097 -27.210 13.151 1.00 85.69 C +ATOM 1682 OD1 ASP A 230 4.033 -27.783 13.429 1.00106.62 O +ATOM 1683 OD2 ASP A 230 5.486 -26.202 13.759 1.00 90.22 O +ATOM 1684 N GLY A 231 6.450 -25.515 9.938 1.00 44.65 N +ATOM 1685 CA GLY A 231 6.535 -24.106 9.661 1.00 43.76 C +ATOM 1686 C GLY A 231 5.720 -23.766 8.440 1.00 51.97 C +ATOM 1687 O GLY A 231 5.182 -22.657 8.327 1.00 64.68 O +ATOM 1688 N ILE A 232 5.715 -24.672 7.464 1.00 71.10 N +ATOM 1689 CA ILE A 232 4.908 -24.484 6.252 1.00101.32 C +ATOM 1690 C ILE A 232 3.439 -24.343 6.651 1.00109.85 C +ATOM 1691 O ILE A 232 2.758 -23.422 6.204 1.00 87.81 O +ATOM 1692 CB ILE A 232 5.095 -25.658 5.230 1.00112.35 C +ATOM 1693 CG1 ILE A 232 6.462 -25.542 4.549 1.00 94.68 C +ATOM 1694 CG2 ILE A 232 3.981 -25.681 4.174 1.00128.72 C +ATOM 1695 CD1 ILE A 232 6.922 -26.816 3.874 1.00 96.21 C +ATOM 1696 N ASP A 233 2.954 -25.298 7.451 1.00133.46 N +ATOM 1697 CA ASP A 233 1.569 -25.299 7.942 1.00103.90 C +ATOM 1698 C ASP A 233 1.253 -24.009 8.679 1.00 91.87 C +ATOM 1699 O ASP A 233 0.244 -23.359 8.385 1.00131.19 O +ATOM 1700 CB ASP A 233 1.312 -26.481 8.886 1.00 94.91 C +ATOM 1701 CG ASP A 233 1.372 -27.837 8.182 1.00106.32 C +ATOM 1702 OD1 ASP A 233 1.847 -27.896 6.996 1.00125.95 O +ATOM 1703 OD2 ASP A 233 1.038 -28.864 8.845 1.00 57.38 O +ATOM 1704 N ARG A 234 2.121 -23.627 9.602 1.00 80.46 N +ATOM 1705 CA ARG A 234 1.854 -22.474 10.455 1.00 86.28 C +ATOM 1706 C ARG A 234 2.121 -21.115 9.805 1.00 87.12 C +ATOM 1707 O ARG A 234 1.934 -20.067 10.433 1.00 89.08 O +ATOM 1708 CB ARG A 234 2.642 -22.609 11.755 1.00 78.20 C +ATOM 1709 CG ARG A 234 2.052 -23.678 12.636 1.00 87.80 C +ATOM 1710 CD ARG A 234 3.046 -24.204 13.645 1.00101.90 C +ATOM 1711 NE ARG A 234 2.459 -25.316 14.406 1.00126.15 N +ATOM 1712 CZ ARG A 234 2.341 -25.358 15.732 1.00121.52 C +ATOM 1713 NH1 ARG A 234 2.793 -24.344 16.464 1.00159.20 N +ATOM 1714 NH2 ARG A 234 1.768 -26.407 16.326 1.00 82.63 N +ATOM 1715 N GLY A 235 2.588 -21.117 8.560 1.00107.06 N +ATOM 1716 CA GLY A 235 2.866 -19.861 7.850 1.00119.36 C +ATOM 1717 C GLY A 235 4.114 -19.100 8.330 1.00100.26 C +ATOM 1718 O GLY A 235 4.148 -17.883 8.266 1.00 57.07 O +ATOM 1719 N LEU A 236 5.150 -19.828 8.761 1.00102.75 N +ATOM 1720 CA LEU A 236 6.487 -19.237 8.956 1.00 65.71 C +ATOM 1721 C LEU A 236 7.170 -18.995 7.618 1.00 64.72 C +ATOM 1722 O LEU A 236 7.585 -17.879 7.326 1.00 85.94 O +ATOM 1723 CB LEU A 236 7.372 -20.149 9.774 1.00 83.15 C +ATOM 1724 CG LEU A 236 7.231 -20.115 11.301 1.00123.65 C +ATOM 1725 CD1 LEU A 236 6.027 -20.935 11.748 1.00171.06 C +ATOM 1726 CD2 LEU A 236 8.490 -20.653 11.972 1.00108.14 C +ATOM 1727 N TRP A 237 7.170 -20.007 6.747 1.00 67.61 N +ATOM 1728 CA TRP A 237 7.732 -19.893 5.377 1.00 75.88 C +ATOM 1729 C TRP A 237 6.876 -20.635 4.316 1.00 91.33 C +ATOM 1730 O TRP A 237 5.897 -21.287 4.665 1.00125.11 O +ATOM 1731 CB TRP A 237 9.113 -20.487 5.375 1.00 65.91 C +ATOM 1732 CG TRP A 237 9.231 -21.631 6.277 1.00 72.46 C +ATOM 1733 CD1 TRP A 237 8.650 -22.846 6.117 1.00 92.57 C +ATOM 1734 CD2 TRP A 237 10.001 -21.713 7.494 1.00 87.71 C +ATOM 1735 NE1 TRP A 237 8.995 -23.678 7.159 1.00114.06 N +ATOM 1736 CE2 TRP A 237 9.819 -23.001 8.019 1.00111.37 C +ATOM 1737 CE3 TRP A 237 10.821 -20.823 8.191 1.00102.83 C +ATOM 1738 CZ2 TRP A 237 10.412 -23.416 9.232 1.00127.17 C +ATOM 1739 CZ3 TRP A 237 11.399 -21.229 9.417 1.00 92.29 C +ATOM 1740 CH2 TRP A 237 11.193 -22.510 9.910 1.00107.91 C +ATOM 1741 N ASP A 238 7.127 -20.414 3.025 1.00 94.79 N +ATOM 1742 CA ASP A 238 6.268 -21.020 1.965 1.00103.34 C +ATOM 1743 C ASP A 238 7.044 -21.542 0.785 1.00 94.97 C +ATOM 1744 O ASP A 238 8.151 -21.057 0.450 1.00103.32 O +ATOM 1745 CB ASP A 238 5.033 -20.113 1.516 1.00129.95 C +ATOM 1746 CG ASP A 238 3.644 -20.762 1.921 1.00134.70 C +ATOM 1747 OD1 ASP A 238 3.245 -21.840 1.375 1.00118.81 O +ATOM 1748 OD2 ASP A 238 3.046 -20.296 2.920 1.00122.01 O +ATOM 1749 N LEU A 239 6.357 -22.425 0.070 1.00 97.62 N +ATOM 1750 CA LEU A 239 6.940 -23.143 -1.045 1.00101.44 C +ATOM 1751 C LEU A 239 7.018 -22.318 -2.328 1.00106.59 C +ATOM 1752 O LEU A 239 6.121 -21.492 -2.619 1.00140.65 O +ATOM 1753 CB LEU A 239 6.130 -24.410 -1.332 1.00 88.03 C +ATOM 1754 CG LEU A 239 6.238 -25.585 -0.373 1.00 80.71 C +ATOM 1755 CD1 LEU A 239 5.473 -26.775 -0.916 1.00 55.13 C +ATOM 1756 CD2 LEU A 239 7.690 -25.952 -0.166 1.00102.25 C +ATOM 1757 N GLN A 240 8.082 -22.558 -3.096 1.00 80.30 N +ATOM 1758 CA GLN A 240 8.224 -21.970 -4.438 1.00 90.39 C +ATOM 1759 C GLN A 240 7.077 -22.375 -5.338 1.00 87.67 C +ATOM 1760 O GLN A 240 6.326 -21.523 -5.832 1.00106.69 O +ATOM 1761 CB GLN A 240 9.525 -22.429 -5.086 1.00105.04 C +ATOM 1762 CG GLN A 240 9.844 -21.746 -6.413 1.00105.63 C +ATOM 1763 CD GLN A 240 10.111 -20.254 -6.244 1.00120.53 C +ATOM 1764 OE1 GLN A 240 11.208 -19.851 -5.852 1.00138.73 O +ATOM 1765 NE2 GLN A 240 9.091 -19.431 -6.488 1.00107.89 N +ATOM 1766 N ASN A 241 6.873 -23.683 -5.450 1.00103.29 N +ATOM 1767 CA ASN A 241 5.745 -24.256 -6.205 1.00133.68 C +ATOM 1768 C ASN A 241 4.614 -24.768 -5.318 1.00142.28 C +ATOM 1769 O ASN A 241 4.793 -25.719 -4.539 1.00163.21 O +ATOM 1770 CB ASN A 241 6.235 -25.426 -7.027 1.00147.99 C +ATOM 1771 CG ASN A 241 6.477 -25.065 -8.464 1.00194.35 C +ATOM 1772 OD1 ASN A 241 5.653 -25.362 -9.321 1.00201.05 O +ATOM 1773 ND2 ASN A 241 7.587 -24.373 -8.733 1.00236.27 N +ATOM 1774 N LYS A 242 3.465 -24.090 -5.390 1.00129.93 N +ATOM 1775 CA LYS A 242 2.333 -24.402 -4.520 1.00112.32 C +ATOM 1776 C LYS A 242 1.794 -25.746 -4.972 1.00 85.84 C +ATOM 1777 O LYS A 242 1.215 -26.483 -4.142 1.00102.98 O +ATOM 1778 CB LYS A 242 1.256 -23.316 -4.617 1.00119.15 C +ATOM 1779 CG LYS A 242 1.776 -21.899 -4.390 1.00151.82 C +ATOM 1780 CD LYS A 242 1.017 -21.157 -3.314 1.00184.60 C +ATOM 1781 CE LYS A 242 1.962 -20.465 -2.339 1.00219.38 C +ATOM 1782 NZ LYS A 242 1.234 -19.573 -1.394 1.00242.90 N +ATOM 1783 N ALA A 243 2.084 -26.092 -6.224 1.00 59.37 N +ATOM 1784 CA ALA A 243 1.784 -27.407 -6.790 1.00 61.84 C +ATOM 1785 C ALA A 243 2.567 -28.529 -6.117 1.00 82.80 C +ATOM 1786 O ALA A 243 2.143 -29.692 -6.152 1.00131.78 O +ATOM 1787 CB ALA A 243 2.099 -27.422 -8.259 1.00 49.38 C +ATOM 1788 N GLU A 244 3.636 -28.183 -5.412 1.00 88.79 N +ATOM 1789 CA GLU A 244 4.432 -29.193 -4.737 1.00 84.79 C +ATOM 1790 C GLU A 244 4.015 -29.490 -3.294 1.00 75.01 C +ATOM 1791 O GLU A 244 4.788 -30.078 -2.538 1.00 96.65 O +ATOM 1792 CB GLU A 244 5.915 -28.797 -4.813 1.00110.44 C +ATOM 1793 CG GLU A 244 6.513 -28.943 -6.213 1.00116.07 C +ATOM 1794 CD GLU A 244 8.025 -28.807 -6.254 1.00116.91 C +ATOM 1795 OE1 GLU A 244 8.538 -27.676 -6.127 1.00131.33 O +ATOM 1796 OE2 GLU A 244 8.705 -29.848 -6.327 1.00128.90 O +ATOM 1797 N ARG A 245 2.871 -28.951 -2.876 1.00 67.76 N +ATOM 1798 CA ARG A 245 2.306 -29.150 -1.537 1.00 77.22 C +ATOM 1799 C ARG A 245 2.156 -30.660 -1.248 1.00 72.07 C +ATOM 1800 O ARG A 245 2.459 -31.156 -0.109 1.00109.53 O +ATOM 1801 CB ARG A 245 0.899 -28.375 -1.475 1.00 90.58 C +ATOM 1802 CG ARG A 245 1.000 -26.858 -1.248 1.00107.73 C +ATOM 1803 CD ARG A 245 -0.232 -26.090 -1.567 1.00102.09 C +ATOM 1804 NE ARG A 245 -0.169 -24.718 -1.132 1.00139.32 N +ATOM 1805 CZ ARG A 245 -1.201 -23.884 -1.184 1.00140.35 C +ATOM 1806 NH1 ARG A 245 -2.417 -24.305 -1.520 1.00156.70 N +ATOM 1807 NH2 ARG A 245 -1.021 -22.628 -0.828 1.00172.01 N +ATOM 1808 N GLN A 246 1.766 -31.407 -2.275 1.00 60.69 N +ATOM 1809 CA GLN A 246 1.493 -32.824 -2.092 1.00 73.63 C +ATOM 1810 C GLN A 246 2.702 -33.680 -2.487 1.00 74.50 C +ATOM 1811 O GLN A 246 2.573 -34.888 -2.708 1.00 55.20 O +ATOM 1812 CB GLN A 246 0.282 -33.259 -2.911 1.00 79.89 C +ATOM 1813 CG GLN A 246 -1.055 -32.740 -2.412 1.00 78.14 C +ATOM 1814 CD GLN A 246 -1.284 -31.297 -2.766 1.00 94.67 C +ATOM 1815 OE1 GLN A 246 -0.979 -30.863 -3.868 1.00114.09 O +ATOM 1816 NE2 GLN A 246 -1.769 -30.525 -1.803 1.00127.02 N +ATOM 1817 N ASN A 247 3.883 -33.081 -2.426 1.00 86.87 N +ATOM 1818 CA ASN A 247 5.151 -33.811 -2.451 1.00101.75 C +ATOM 1819 C ASN A 247 5.128 -35.090 -1.613 1.00 93.49 C +ATOM 1820 O ASN A 247 4.630 -35.088 -0.471 1.00108.34 O +ATOM 1821 CB ASN A 247 6.270 -32.893 -1.925 1.00115.50 C +ATOM 1822 CG ASN A 247 7.624 -33.225 -2.499 1.00107.43 C +ATOM 1823 OD1 ASN A 247 8.478 -33.776 -1.812 1.00 82.50 O +ATOM 1824 ND2 ASN A 247 7.809 -32.936 -3.780 1.00100.73 N +ATOM 1825 N ASP A 248 5.693 -36.167 -2.161 1.00 89.62 N +ATOM 1826 CA ASP A 248 5.684 -37.481 -1.492 1.00109.98 C +ATOM 1827 C ASP A 248 6.230 -37.375 -0.066 1.00105.02 C +ATOM 1828 O ASP A 248 5.668 -37.942 0.890 1.00114.60 O +ATOM 1829 CB ASP A 248 6.533 -38.496 -2.276 1.00107.11 C +ATOM 1830 CG ASP A 248 5.892 -38.914 -3.579 1.00115.93 C +ATOM 1831 OD1 ASP A 248 4.650 -39.082 -3.625 1.00145.43 O +ATOM 1832 OD2 ASP A 248 6.631 -39.110 -4.559 1.00112.90 O +ATOM 1833 N ILE A 249 7.346 -36.669 0.061 1.00 91.34 N +ATOM 1834 CA ILE A 249 8.056 -36.571 1.324 1.00 95.96 C +ATOM 1835 C ILE A 249 7.216 -35.776 2.320 1.00 77.08 C +ATOM 1836 O ILE A 249 6.997 -36.212 3.453 1.00 82.76 O +ATOM 1837 CB ILE A 249 9.440 -35.915 1.118 1.00100.99 C +ATOM 1838 CG1 ILE A 249 10.316 -36.789 0.206 1.00121.84 C +ATOM 1839 CG2 ILE A 249 10.141 -35.720 2.447 1.00 87.81 C +ATOM 1840 CD1 ILE A 249 11.461 -36.048 -0.456 1.00123.39 C +ATOM 1841 N LEU A 250 6.732 -34.625 1.874 1.00 72.39 N +ATOM 1842 CA LEU A 250 5.955 -33.727 2.730 1.00 70.84 C +ATOM 1843 C LEU A 250 4.682 -34.375 3.271 1.00 75.26 C +ATOM 1844 O LEU A 250 4.317 -34.155 4.430 1.00 83.60 O +ATOM 1845 CB LEU A 250 5.596 -32.446 1.979 1.00 60.07 C +ATOM 1846 CG LEU A 250 6.711 -31.412 1.912 1.00 60.33 C +ATOM 1847 CD1 LEU A 250 6.404 -30.296 0.919 1.00 57.25 C +ATOM 1848 CD2 LEU A 250 6.969 -30.822 3.291 1.00 73.83 C +ATOM 1849 N VAL A 251 4.039 -35.195 2.447 1.00 73.70 N +ATOM 1850 CA VAL A 251 2.822 -35.894 2.867 1.00 82.96 C +ATOM 1851 C VAL A 251 3.151 -37.100 3.743 1.00 88.37 C +ATOM 1852 O VAL A 251 2.328 -37.534 4.558 1.00119.90 O +ATOM 1853 CB VAL A 251 1.947 -36.344 1.661 1.00 87.33 C +ATOM 1854 CG1 VAL A 251 1.623 -35.150 0.752 1.00107.80 C +ATOM 1855 CG2 VAL A 251 2.609 -37.463 0.872 1.00 74.58 C +ATOM 1856 N LYS A 252 4.359 -37.632 3.587 1.00 86.02 N +ATOM 1857 CA LYS A 252 4.826 -38.743 4.425 1.00 74.33 C +ATOM 1858 C LYS A 252 5.054 -38.283 5.873 1.00 68.39 C +ATOM 1859 O LYS A 252 4.570 -38.905 6.823 1.00 82.48 O +ATOM 1860 CB LYS A 252 6.105 -39.311 3.831 1.00 82.47 C +ATOM 1861 CG LYS A 252 6.728 -40.451 4.606 1.00 99.12 C +ATOM 1862 CD LYS A 252 8.028 -40.902 3.942 1.00111.05 C +ATOM 1863 CE LYS A 252 9.158 -41.050 4.954 1.00125.00 C +ATOM 1864 NZ LYS A 252 10.484 -41.234 4.308 1.00123.25 N +ATOM 1865 N TYR A 253 5.709 -37.138 6.032 1.00 71.75 N +ATOM 1866 CA TYR A 253 5.969 -36.568 7.366 1.00 80.23 C +ATOM 1867 C TYR A 253 4.692 -35.974 7.952 1.00 73.25 C +ATOM 1868 O TYR A 253 4.517 -35.912 9.163 1.00 53.53 O +ATOM 1869 CB TYR A 253 7.122 -35.524 7.331 1.00 87.56 C +ATOM 1870 CG TYR A 253 8.471 -36.170 7.187 1.00 91.88 C +ATOM 1871 CD1 TYR A 253 8.930 -36.497 5.920 1.00126.45 C +ATOM 1872 CD2 TYR A 253 9.244 -36.544 8.289 1.00 69.25 C +ATOM 1873 CE1 TYR A 253 10.119 -37.176 5.725 1.00133.53 C +ATOM 1874 CE2 TYR A 253 10.452 -37.201 8.094 1.00 84.15 C +ATOM 1875 CZ TYR A 253 10.874 -37.538 6.814 1.00109.87 C +ATOM 1876 OH TYR A 253 12.002 -38.326 6.586 1.00110.71 O +ATOM 1877 N ARG A 254 3.853 -35.430 7.074 1.00 91.76 N +ATOM 1878 CA ARG A 254 2.536 -34.943 7.485 1.00 91.44 C +ATOM 1879 C ARG A 254 1.798 -36.098 8.128 1.00 70.14 C +ATOM 1880 O ARG A 254 1.049 -35.887 9.082 1.00 79.52 O +ATOM 1881 CB ARG A 254 1.732 -34.353 6.281 1.00 92.53 C +ATOM 1882 CG ARG A 254 0.234 -34.109 6.625 1.00 73.91 C +ATOM 1883 CD ARG A 254 0.025 -33.020 7.726 1.00 66.50 C +ATOM 1884 NE ARG A 254 1.112 -32.035 7.745 1.00 67.06 N +ATOM 1885 CZ ARG A 254 1.130 -30.962 6.998 1.00 70.59 C +ATOM 1886 NH1 ARG A 254 0.042 -30.619 6.351 1.00 92.21 N +ATOM 1887 NH2 ARG A 254 2.210 -30.201 6.932 1.00111.81 N +ATOM 1888 N HIS A 255 1.917 -37.268 7.504 1.00 70.27 N +ATOM 1889 CA HIS A 255 1.208 -38.467 7.943 1.00 81.27 C +ATOM 1890 C HIS A 255 1.741 -38.982 9.269 1.00 74.11 C +ATOM 1891 O HIS A 255 0.970 -39.470 10.093 1.00 83.07 O +ATOM 1892 CB HIS A 255 1.256 -39.571 6.880 1.00 94.26 C +ATOM 1893 CG HIS A 255 -0.057 -39.800 6.184 1.00123.07 C +ATOM 1894 ND1 HIS A 255 -1.019 -40.647 6.692 1.00155.42 N +ATOM 1895 CD2 HIS A 255 -0.601 -39.243 5.072 1.00144.74 C +ATOM 1896 CE1 HIS A 255 -2.095 -40.609 5.928 1.00174.77 C +ATOM 1897 NE2 HIS A 255 -1.863 -39.776 4.929 1.00182.64 N +ATOM 1898 N MET A 256 3.026 -38.775 9.526 1.00 88.12 N +ATOM 1899 CA MET A 256 3.613 -39.207 10.805 1.00 91.38 C +ATOM 1900 C MET A 256 3.189 -38.317 11.981 1.00 70.60 C +ATOM 1901 O MET A 256 3.053 -38.791 13.118 1.00 67.85 O +ATOM 1902 CB MET A 256 5.138 -39.239 10.729 1.00 97.29 C +ATOM 1903 CG MET A 256 5.690 -40.045 9.566 1.00101.35 C +ATOM 1904 SD MET A 256 7.416 -40.535 9.727 1.00 97.62 S +ATOM 1905 CE MET A 256 7.275 -41.760 11.050 1.00 98.59 C +ATOM 1906 N SER A 257 2.843 -37.072 11.703 1.00 61.60 N +ATOM 1907 CA SER A 257 2.296 -36.216 12.758 1.00 68.83 C +ATOM 1908 C SER A 257 0.926 -36.722 13.250 1.00 79.00 C +ATOM 1909 O SER A 257 0.736 -37.176 14.381 1.00 81.28 O +ATOM 1910 CB SER A 257 2.167 -34.790 12.211 1.00 78.22 C +ATOM 1911 OG SER A 257 3.324 -34.418 11.527 1.00103.82 O +TER 1912 SER A 257 +ATOM 1913 N LEU B 2 32.405 -55.517 3.173 1.00154.04 N +ATOM 1914 CA LEU B 2 31.788 -55.656 4.534 1.00157.26 C +ATOM 1915 C LEU B 2 32.852 -55.434 5.644 1.00148.08 C +ATOM 1916 O LEU B 2 33.271 -56.380 6.365 1.00 63.56 O +ATOM 1917 CB LEU B 2 31.075 -57.013 4.685 1.00159.45 C +ATOM 1918 CG LEU B 2 29.891 -57.353 3.744 1.00120.03 C +ATOM 1919 CD1 LEU B 2 29.376 -58.758 4.066 1.00105.71 C +ATOM 1920 CD2 LEU B 2 28.741 -56.342 3.772 1.00 98.78 C +ATOM 1921 N THR B 3 33.354 -54.192 5.650 1.00160.57 N +ATOM 1922 CA THR B 3 34.095 -53.589 6.758 1.00153.94 C +ATOM 1923 C THR B 3 33.727 -52.093 6.924 1.00155.62 C +ATOM 1924 O THR B 3 34.219 -51.419 7.833 1.00150.07 O +ATOM 1925 CB THR B 3 35.625 -53.675 6.549 1.00129.37 C +ATOM 1926 OG1 THR B 3 36.013 -52.819 5.455 1.00 98.55 O +ATOM 1927 CG2 THR B 3 36.074 -55.123 6.301 1.00124.27 C +ATOM 1928 N ALA B 4 32.932 -51.563 5.998 1.00137.77 N +ATOM 1929 CA ALA B 4 32.331 -50.233 6.156 1.00125.95 C +ATOM 1930 C ALA B 4 31.135 -50.318 7.138 1.00113.39 C +ATOM 1931 O ALA B 4 30.902 -51.373 7.728 1.00 94.26 O +ATOM 1932 CB ALA B 4 31.935 -49.673 4.783 1.00117.92 C +ATOM 1933 N PRO B 5 30.409 -49.203 7.376 1.00112.25 N +ATOM 1934 CA PRO B 5 29.477 -49.344 8.489 1.00103.59 C +ATOM 1935 C PRO B 5 28.198 -50.155 8.165 1.00118.85 C +ATOM 1936 O PRO B 5 27.935 -50.483 6.994 1.00141.70 O +ATOM 1937 CB PRO B 5 29.123 -47.896 8.819 1.00101.50 C +ATOM 1938 CG PRO B 5 29.268 -47.150 7.524 1.00112.40 C +ATOM 1939 CD PRO B 5 30.164 -47.956 6.615 1.00118.00 C +ATOM 1940 N PRO B 6 27.418 -50.513 9.206 1.00104.15 N +ATOM 1941 CA PRO B 6 26.063 -51.071 9.028 1.00100.11 C +ATOM 1942 C PRO B 6 25.017 -50.001 8.716 1.00 95.95 C +ATOM 1943 O PRO B 6 25.209 -48.847 9.102 1.00 91.50 O +ATOM 1944 CB PRO B 6 25.767 -51.750 10.377 1.00 87.87 C +ATOM 1945 CG PRO B 6 26.747 -51.220 11.348 1.00 75.45 C +ATOM 1946 CD PRO B 6 27.894 -50.601 10.597 1.00 91.98 C +ATOM 1947 N LYS B 7 23.941 -50.380 8.020 1.00 91.00 N +ATOM 1948 CA LYS B 7 22.917 -49.411 7.608 1.00111.80 C +ATOM 1949 C LYS B 7 21.737 -49.396 8.565 1.00 91.97 C +ATOM 1950 O LYS B 7 21.657 -50.262 9.455 1.00 84.73 O +ATOM 1951 CB LYS B 7 22.418 -49.685 6.191 1.00124.62 C +ATOM 1952 CG LYS B 7 23.434 -49.421 5.104 1.00148.10 C +ATOM 1953 CD LYS B 7 24.036 -50.697 4.522 1.00134.70 C +ATOM 1954 CE LYS B 7 24.794 -50.394 3.239 1.00153.26 C +ATOM 1955 NZ LYS B 7 25.918 -51.343 3.011 1.00152.35 N +ATOM 1956 N GLU B 8 20.880 -48.378 8.418 1.00 73.07 N +ATOM 1957 CA GLU B 8 19.922 -48.028 9.467 1.00 77.59 C +ATOM 1958 C GLU B 8 18.871 -49.112 9.664 1.00 76.20 C +ATOM 1959 O GLU B 8 18.129 -49.444 8.750 1.00 64.54 O +ATOM 1960 CB GLU B 8 19.250 -46.649 9.215 1.00102.02 C +ATOM 1961 CG GLU B 8 18.093 -46.568 8.240 1.00133.63 C +ATOM 1962 CD GLU B 8 17.377 -45.208 8.278 1.00153.44 C +ATOM 1963 OE1 GLU B 8 16.919 -44.767 9.357 1.00146.56 O +ATOM 1964 OE2 GLU B 8 17.200 -44.593 7.217 1.00176.46 O +ATOM 1965 N ALA B 9 18.809 -49.643 10.879 1.00 73.56 N +ATOM 1966 CA ALA B 9 17.776 -50.584 11.263 1.00 71.11 C +ATOM 1967 C ALA B 9 16.682 -49.832 12.013 1.00 70.74 C +ATOM 1968 O ALA B 9 16.897 -49.359 13.128 1.00 59.47 O +ATOM 1969 CB ALA B 9 18.372 -51.674 12.140 1.00 73.58 C +ATOM 1970 N ALA B 10 15.500 -49.769 11.391 1.00 65.41 N +ATOM 1971 CA ALA B 10 14.342 -48.982 11.857 1.00 61.76 C +ATOM 1972 C ALA B 10 14.474 -47.565 11.365 1.00 70.55 C +ATOM 1973 O ALA B 10 15.569 -47.109 11.030 1.00 62.78 O +ATOM 1974 CB ALA B 10 14.166 -49.027 13.379 1.00 58.17 C +ATOM 1975 N ARG B 11 13.349 -46.867 11.319 1.00 93.33 N +ATOM 1976 CA ARG B 11 13.316 -45.477 10.845 1.00108.84 C +ATOM 1977 C ARG B 11 13.243 -44.523 12.037 1.00 94.96 C +ATOM 1978 O ARG B 11 12.698 -44.878 13.070 1.00103.02 O +ATOM 1979 CB ARG B 11 12.089 -45.248 9.943 1.00141.38 C +ATOM 1980 CG ARG B 11 10.741 -45.367 10.650 1.00166.52 C +ATOM 1981 CD ARG B 11 9.637 -45.779 9.678 1.00174.40 C +ATOM 1982 NE ARG B 11 9.158 -47.138 9.926 1.00178.38 N +ATOM 1983 CZ ARG B 11 8.191 -47.726 9.227 1.00154.06 C +ATOM 1984 NH1 ARG B 11 7.571 -47.061 8.260 1.00134.11 N +ATOM 1985 NH2 ARG B 11 7.834 -48.976 9.501 1.00145.31 N +ATOM 1986 N PRO B 12 13.750 -43.290 11.882 1.00 92.06 N +ATOM 1987 CA PRO B 12 13.389 -42.276 12.861 1.00 91.08 C +ATOM 1988 C PRO B 12 11.888 -41.974 12.818 1.00 96.12 C +ATOM 1989 O PRO B 12 11.375 -41.480 11.818 1.00 82.91 O +ATOM 1990 CB PRO B 12 14.207 -41.050 12.427 1.00 93.66 C +ATOM 1991 CG PRO B 12 15.197 -41.541 11.420 1.00 95.17 C +ATOM 1992 CD PRO B 12 14.560 -42.731 10.785 1.00100.97 C +ATOM 1993 N THR B 13 11.191 -42.324 13.892 1.00101.86 N +ATOM 1994 CA THR B 13 9.823 -41.877 14.117 1.00 98.68 C +ATOM 1995 C THR B 13 9.789 -40.644 15.015 1.00 87.89 C +ATOM 1996 O THR B 13 10.772 -40.352 15.709 1.00104.65 O +ATOM 1997 CB THR B 13 9.021 -42.978 14.805 1.00108.95 C +ATOM 1998 OG1 THR B 13 7.636 -42.627 14.801 1.00179.54 O +ATOM 1999 CG2 THR B 13 9.523 -43.238 16.263 1.00102.45 C +ATOM 2000 N LEU B 14 8.690 -39.899 15.015 1.00 72.40 N +ATOM 2001 CA LEU B 14 8.590 -38.847 16.020 1.00 83.20 C +ATOM 2002 C LEU B 14 8.317 -39.531 17.349 1.00 76.61 C +ATOM 2003 O LEU B 14 7.841 -40.658 17.373 1.00 68.39 O +ATOM 2004 CB LEU B 14 7.606 -37.718 15.647 1.00 77.38 C +ATOM 2005 CG LEU B 14 6.220 -38.092 15.204 1.00 92.75 C +ATOM 2006 CD1 LEU B 14 5.209 -37.036 15.632 1.00113.50 C +ATOM 2007 CD2 LEU B 14 6.206 -38.231 13.699 1.00106.25 C +ATOM 2008 N MET B 15 8.679 -38.881 18.450 1.00 82.88 N +ATOM 2009 CA MET B 15 8.604 -39.507 19.769 1.00 98.07 C +ATOM 2010 C MET B 15 7.334 -40.232 20.211 1.00 95.66 C +ATOM 2011 O MET B 15 6.263 -39.628 20.279 1.00130.27 O +ATOM 2012 CB MET B 15 8.730 -38.451 20.870 1.00114.03 C +ATOM 2013 CG MET B 15 9.484 -38.925 22.102 1.00120.04 C +ATOM 2014 SD MET B 15 9.183 -37.886 23.544 1.00128.68 S +ATOM 2015 CE MET B 15 8.284 -39.021 24.598 1.00 90.31 C +ATOM 2016 N PRO B 16 7.452 -41.523 20.517 1.00 88.52 N +ATOM 2017 CA PRO B 16 6.262 -42.340 20.807 1.00 88.42 C +ATOM 2018 C PRO B 16 5.595 -42.037 22.146 1.00 91.46 C +ATOM 2019 O PRO B 16 5.858 -42.703 23.165 1.00127.74 O +ATOM 2020 CB PRO B 16 6.821 -43.765 20.809 1.00123.27 C +ATOM 2021 CG PRO B 16 8.285 -43.612 21.094 1.00130.18 C +ATOM 2022 CD PRO B 16 8.665 -42.351 20.399 1.00116.59 C +ATOM 2023 N ARG B 17 4.755 -41.014 22.158 1.00 84.59 N +ATOM 2024 CA ARG B 17 3.976 -40.653 23.355 1.00 78.51 C +ATOM 2025 C ARG B 17 2.686 -41.415 23.331 1.00 76.60 C +ATOM 2026 O ARG B 17 2.159 -41.680 22.247 1.00 74.10 O +ATOM 2027 CB ARG B 17 3.693 -39.150 23.373 1.00 77.58 C +ATOM 2028 CG ARG B 17 4.795 -38.351 24.055 1.00118.39 C +ATOM 2029 CD ARG B 17 4.777 -36.862 23.727 1.00111.27 C +ATOM 2030 NE ARG B 17 5.327 -36.589 22.393 1.00140.31 N +ATOM 2031 CZ ARG B 17 5.315 -35.398 21.805 1.00154.33 C +ATOM 2032 NH1 ARG B 17 4.788 -34.369 22.461 1.00183.91 N +ATOM 2033 NH2 ARG B 17 5.826 -35.234 20.575 1.00119.62 N +ATOM 2034 N ALA B 18 2.156 -41.789 24.497 1.00 83.30 N +ATOM 2035 CA ALA B 18 0.916 -42.597 24.548 1.00105.39 C +ATOM 2036 C ALA B 18 -0.299 -41.849 25.136 1.00101.44 C +ATOM 2037 O ALA B 18 -0.761 -40.854 24.548 1.00130.41 O +ATOM 2038 CB ALA B 18 1.147 -43.918 25.274 1.00 99.10 C +ATOM 2039 N GLN B 19 -0.861 -42.367 26.226 1.00 86.91 N +ATOM 2040 CA GLN B 19 -2.232 -42.021 26.608 1.00116.58 C +ATOM 2041 C GLN B 19 -2.319 -40.582 27.111 1.00116.34 C +ATOM 2042 O GLN B 19 -3.199 -39.800 26.708 1.00124.72 O +ATOM 2043 CB GLN B 19 -2.739 -42.985 27.688 1.00130.40 C +ATOM 2044 CG GLN B 19 -4.205 -42.790 28.074 1.00141.76 C +ATOM 2045 CD GLN B 19 -5.149 -42.850 26.884 1.00148.72 C +ATOM 2046 OE1 GLN B 19 -5.301 -43.894 26.249 1.00177.95 O +ATOM 2047 NE2 GLN B 19 -5.766 -41.718 26.558 1.00160.00 N +ATOM 2048 N SER B 20 -1.429 -40.269 28.041 1.00106.95 N +ATOM 2049 CA SER B 20 -1.262 -38.922 28.551 1.00112.39 C +ATOM 2050 C SER B 20 -1.316 -37.889 27.421 1.00107.70 C +ATOM 2051 O SER B 20 -2.064 -36.910 27.498 1.00 98.87 O +ATOM 2052 CB SER B 20 0.082 -38.841 29.286 1.00128.38 C +ATOM 2053 OG SER B 20 0.210 -39.900 30.229 1.00158.94 O +ATOM 2054 N TYR B 21 -0.532 -38.128 26.368 1.00112.23 N +ATOM 2055 CA TYR B 21 -0.511 -37.265 25.179 1.00112.95 C +ATOM 2056 C TYR B 21 -1.890 -37.102 24.535 1.00130.87 C +ATOM 2057 O TYR B 21 -2.328 -35.975 24.249 1.00131.92 O +ATOM 2058 CB TYR B 21 0.464 -37.824 24.137 1.00108.74 C +ATOM 2059 CG TYR B 21 0.580 -36.967 22.900 1.00 93.13 C +ATOM 2060 CD1 TYR B 21 1.289 -35.772 22.923 1.00 93.56 C +ATOM 2061 CD2 TYR B 21 -0.034 -37.337 21.715 1.00 88.93 C +ATOM 2062 CE1 TYR B 21 1.381 -34.966 21.808 1.00 80.03 C +ATOM 2063 CE2 TYR B 21 0.088 -36.555 20.585 1.00 80.70 C +ATOM 2064 CZ TYR B 21 0.793 -35.374 20.645 1.00 68.28 C +ATOM 2065 OH TYR B 21 0.912 -34.568 19.546 1.00 77.02 O +ATOM 2066 N LYS B 22 -2.567 -38.226 24.303 1.00119.07 N +ATOM 2067 CA LYS B 22 -3.874 -38.218 23.652 1.00105.89 C +ATOM 2068 C LYS B 22 -4.916 -37.415 24.439 1.00102.32 C +ATOM 2069 O LYS B 22 -5.712 -36.677 23.860 1.00105.06 O +ATOM 2070 CB LYS B 22 -4.370 -39.643 23.472 1.00110.18 C +ATOM 2071 CG LYS B 22 -3.918 -40.279 22.179 1.00145.54 C +ATOM 2072 CD LYS B 22 -4.831 -39.847 21.025 1.00175.52 C +ATOM 2073 CE LYS B 22 -5.828 -40.966 20.686 1.00195.87 C +ATOM 2074 NZ LYS B 22 -5.139 -42.172 20.156 1.00184.63 N +ATOM 2075 N ASP B 23 -4.896 -37.561 25.761 1.00 91.41 N +ATOM 2076 CA ASP B 23 -5.729 -36.749 26.645 1.00 83.32 C +ATOM 2077 C ASP B 23 -5.358 -35.271 26.540 1.00 80.12 C +ATOM 2078 O ASP B 23 -6.221 -34.400 26.469 1.00 87.15 O +ATOM 2079 CB ASP B 23 -5.572 -37.218 28.102 1.00 88.12 C +ATOM 2080 CG ASP B 23 -6.150 -38.582 28.334 1.00105.31 C +ATOM 2081 OD1 ASP B 23 -7.224 -38.864 27.755 1.00116.99 O +ATOM 2082 OD2 ASP B 23 -5.504 -39.391 29.038 1.00119.60 O +ATOM 2083 N LEU B 24 -4.056 -35.003 26.585 1.00 96.33 N +ATOM 2084 CA LEU B 24 -3.525 -33.640 26.653 1.00 99.70 C +ATOM 2085 C LEU B 24 -3.871 -32.840 25.393 1.00100.75 C +ATOM 2086 O LEU B 24 -4.107 -31.614 25.462 1.00 63.49 O +ATOM 2087 CB LEU B 24 -1.999 -33.688 26.851 1.00 99.92 C +ATOM 2088 CG LEU B 24 -1.247 -32.352 26.948 1.00 96.42 C +ATOM 2089 CD1 LEU B 24 -1.241 -31.823 28.374 1.00 85.09 C +ATOM 2090 CD2 LEU B 24 0.179 -32.527 26.443 1.00118.29 C +ATOM 2091 N THR B 25 -3.880 -33.533 24.250 1.00 92.99 N +ATOM 2092 CA THR B 25 -4.115 -32.881 22.971 1.00118.09 C +ATOM 2093 C THR B 25 -5.597 -32.562 22.775 1.00115.11 C +ATOM 2094 O THR B 25 -5.954 -31.434 22.383 1.00134.28 O +ATOM 2095 CB THR B 25 -3.617 -33.745 21.794 1.00125.12 C +ATOM 2096 OG1 THR B 25 -4.038 -35.097 21.976 1.00135.64 O +ATOM 2097 CG2 THR B 25 -2.099 -33.694 21.704 1.00121.48 C +ATOM 2098 N HIS B 26 -6.446 -33.545 23.062 1.00 98.89 N +ATOM 2099 CA HIS B 26 -7.887 -33.416 22.865 1.00 96.36 C +ATOM 2100 C HIS B 26 -8.556 -32.725 24.079 1.00107.57 C +ATOM 2101 O HIS B 26 -9.676 -33.050 24.450 1.00119.30 O +ATOM 2102 CB HIS B 26 -8.511 -34.799 22.588 1.00 89.93 C +ATOM 2103 CG HIS B 26 -8.028 -35.441 21.315 1.00105.20 C +ATOM 2104 ND1 HIS B 26 -6.739 -35.902 21.151 1.00127.32 N +ATOM 2105 CD2 HIS B 26 -8.658 -35.685 20.141 1.00120.44 C +ATOM 2106 CE1 HIS B 26 -6.591 -36.386 19.930 1.00105.59 C +ATOM 2107 NE2 HIS B 26 -7.741 -36.267 19.296 1.00106.60 N +ATOM 2108 N LEU B 27 -7.879 -31.743 24.675 1.00115.42 N +ATOM 2109 CA LEU B 27 -8.469 -30.940 25.753 1.00 99.32 C +ATOM 2110 C LEU B 27 -9.204 -29.736 25.177 1.00106.31 C +ATOM 2111 O LEU B 27 -8.698 -29.069 24.274 1.00116.16 O +ATOM 2112 CB LEU B 27 -7.391 -30.454 26.722 1.00102.54 C +ATOM 2113 CG LEU B 27 -7.051 -31.424 27.856 1.00121.76 C +ATOM 2114 CD1 LEU B 27 -5.773 -31.007 28.562 1.00132.68 C +ATOM 2115 CD2 LEU B 27 -8.192 -31.526 28.852 1.00119.36 C +ATOM 2116 N PRO B 28 -10.412 -29.453 25.690 1.00110.77 N +ATOM 2117 CA PRO B 28 -11.233 -28.333 25.199 1.00109.82 C +ATOM 2118 C PRO B 28 -10.528 -27.011 25.390 1.00 98.32 C +ATOM 2119 O PRO B 28 -10.036 -26.740 26.465 1.00107.29 O +ATOM 2120 CB PRO B 28 -12.479 -28.387 26.090 1.00111.92 C +ATOM 2121 CG PRO B 28 -12.046 -29.121 27.315 1.00108.56 C +ATOM 2122 CD PRO B 28 -11.038 -30.127 26.839 1.00115.49 C +ATOM 2123 N ALA B 29 -10.456 -26.207 24.343 1.00 97.68 N +ATOM 2124 CA ALA B 29 -9.575 -25.049 24.346 1.00 94.65 C +ATOM 2125 C ALA B 29 -10.110 -23.933 25.276 1.00 87.43 C +ATOM 2126 O ALA B 29 -11.316 -23.741 25.403 1.00 72.71 O +ATOM 2127 CB ALA B 29 -9.346 -24.548 22.906 1.00 98.52 C +ATOM 2128 N PRO B 30 -9.200 -23.171 25.903 1.00 90.60 N +ATOM 2129 CA PRO B 30 -9.545 -21.965 26.653 1.00 93.11 C +ATOM 2130 C PRO B 30 -9.948 -20.749 25.781 1.00 79.15 C +ATOM 2131 O PRO B 30 -9.811 -20.801 24.556 1.00 59.69 O +ATOM 2132 CB PRO B 30 -8.240 -21.647 27.377 1.00105.65 C +ATOM 2133 CG PRO B 30 -7.175 -22.109 26.450 1.00107.54 C +ATOM 2134 CD PRO B 30 -7.742 -23.292 25.712 1.00105.58 C +ATOM 2135 N THR B 31 -10.366 -19.652 26.426 1.00 77.23 N +ATOM 2136 CA THR B 31 -10.776 -18.423 25.715 1.00 93.44 C +ATOM 2137 C THR B 31 -9.619 -17.714 25.008 1.00 85.60 C +ATOM 2138 O THR B 31 -9.813 -17.041 24.007 1.00 60.13 O +ATOM 2139 CB THR B 31 -11.482 -17.395 26.643 1.00116.96 C +ATOM 2140 OG1 THR B 31 -10.673 -17.101 27.789 1.00 95.05 O +ATOM 2141 CG2 THR B 31 -12.836 -17.917 27.099 1.00138.64 C +ATOM 2142 N GLY B 32 -8.411 -17.892 25.528 1.00112.18 N +ATOM 2143 CA GLY B 32 -7.188 -17.548 24.804 1.00121.33 C +ATOM 2144 C GLY B 32 -6.057 -18.407 25.346 1.00121.43 C +ATOM 2145 O GLY B 32 -6.113 -18.836 26.488 1.00107.60 O +ATOM 2146 N LYS B 33 -5.024 -18.653 24.539 1.00121.53 N +ATOM 2147 CA LYS B 33 -3.827 -19.399 24.985 1.00107.95 C +ATOM 2148 C LYS B 33 -3.014 -18.502 26.039 1.00 93.89 C +ATOM 2149 O LYS B 33 -3.138 -17.252 26.062 1.00 93.28 O +ATOM 2150 CB LYS B 33 -3.058 -19.948 23.705 1.00105.74 C +ATOM 2151 CG LYS B 33 -3.869 -19.756 22.413 1.00124.06 C +ATOM 2152 CD LYS B 33 -2.988 -19.700 21.182 1.00123.03 C +ATOM 2153 CE LYS B 33 -3.616 -18.828 20.110 1.00 98.06 C +ATOM 2154 NZ LYS B 33 -2.673 -18.608 18.975 1.00109.41 N +ATOM 2155 N ILE B 34 -2.437 -19.137 27.061 1.00 84.64 N +ATOM 2156 CA ILE B 34 -1.808 -18.422 28.178 1.00 95.05 C +ATOM 2157 C ILE B 34 -0.281 -18.458 27.973 1.00113.58 C +ATOM 2158 O ILE B 34 0.246 -19.410 27.389 1.00137.78 O +ATOM 2159 CB ILE B 34 -2.257 -19.001 29.552 1.00106.40 C +ATOM 2160 CG1 ILE B 34 -3.746 -18.720 29.791 1.00120.22 C +ATOM 2161 CG2 ILE B 34 -1.489 -18.385 30.723 1.00124.13 C +ATOM 2162 CD1 ILE B 34 -4.587 -19.969 29.916 1.00134.09 C +ATOM 2163 N PHE B 35 0.383 -17.350 28.308 1.00 97.61 N +ATOM 2164 CA PHE B 35 1.816 -17.196 28.140 1.00 97.15 C +ATOM 2165 C PHE B 35 2.553 -17.798 29.323 1.00110.42 C +ATOM 2166 O PHE B 35 2.296 -17.399 30.462 1.00157.12 O +ATOM 2167 CB PHE B 35 2.159 -15.710 28.100 1.00119.68 C +ATOM 2168 CG PHE B 35 2.052 -15.086 26.736 1.00110.93 C +ATOM 2169 CD1 PHE B 35 2.571 -15.718 25.618 1.00 99.19 C +ATOM 2170 CD2 PHE B 35 1.556 -13.800 26.607 1.00121.75 C +ATOM 2171 CE1 PHE B 35 2.522 -15.109 24.385 1.00110.00 C +ATOM 2172 CE2 PHE B 35 1.533 -13.174 25.381 1.00116.67 C +ATOM 2173 CZ PHE B 35 2.007 -13.835 24.266 1.00118.61 C +ATOM 2174 N VAL B 36 3.501 -18.698 29.065 1.00 85.53 N +ATOM 2175 CA VAL B 36 4.149 -19.394 30.150 1.00 61.85 C +ATOM 2176 C VAL B 36 5.633 -19.444 30.000 1.00 63.73 C +ATOM 2177 O VAL B 36 6.174 -19.433 28.904 1.00 79.68 O +ATOM 2178 CB VAL B 36 3.623 -20.818 30.261 1.00 68.34 C +ATOM 2179 CG1 VAL B 36 4.182 -21.701 29.157 1.00 72.17 C +ATOM 2180 CG2 VAL B 36 3.950 -21.391 31.623 1.00 71.58 C +ATOM 2181 N SER B 37 6.313 -19.532 31.126 1.00 80.48 N +ATOM 2182 CA SER B 37 7.770 -19.576 31.140 1.00 83.19 C +ATOM 2183 C SER B 37 8.176 -20.833 31.857 1.00 69.67 C +ATOM 2184 O SER B 37 7.771 -21.043 32.982 1.00 90.59 O +ATOM 2185 CB SER B 37 8.353 -18.351 31.880 1.00 69.69 C +ATOM 2186 OG SER B 37 8.248 -17.169 31.096 1.00 56.09 O +ATOM 2187 N VAL B 38 9.103 -21.585 31.284 1.00 82.16 N +ATOM 2188 CA VAL B 38 9.818 -22.608 32.068 1.00 80.64 C +ATOM 2189 C VAL B 38 11.338 -22.378 32.075 1.00 76.10 C +ATOM 2190 O VAL B 38 11.950 -22.338 30.993 1.00 98.23 O +ATOM 2191 CB VAL B 38 9.572 -24.006 31.502 1.00 69.05 C +ATOM 2192 CG1 VAL B 38 10.340 -25.008 32.319 1.00 61.91 C +ATOM 2193 CG2 VAL B 38 8.093 -24.339 31.474 1.00 64.92 C +ATOM 2194 N TYR B 39 11.920 -22.191 33.270 1.00 69.93 N +ATOM 2195 CA TYR B 39 13.361 -21.848 33.434 1.00 67.25 C +ATOM 2196 C TYR B 39 14.161 -23.128 33.627 1.00 65.82 C +ATOM 2197 O TYR B 39 15.047 -23.432 32.831 1.00102.64 O +ATOM 2198 CB TYR B 39 13.597 -20.879 34.600 1.00 53.83 C +ATOM 2199 CG TYR B 39 13.443 -19.426 34.222 1.00 66.59 C +ATOM 2200 CD1 TYR B 39 12.174 -18.849 34.019 1.00 71.26 C +ATOM 2201 CD2 TYR B 39 14.559 -18.625 34.012 1.00 93.09 C +ATOM 2202 CE1 TYR B 39 12.042 -17.518 33.664 1.00 79.99 C +ATOM 2203 CE2 TYR B 39 14.448 -17.275 33.669 1.00108.19 C +ATOM 2204 CZ TYR B 39 13.189 -16.721 33.509 1.00109.28 C +ATOM 2205 OH TYR B 39 13.087 -15.408 33.070 1.00 96.03 O +ATOM 2206 N ASN B 40 13.706 -23.982 34.524 1.00 59.51 N +ATOM 2207 CA ASN B 40 14.377 -25.248 34.736 1.00 60.68 C +ATOM 2208 C ASN B 40 13.613 -26.223 35.645 1.00 66.25 C +ATOM 2209 O ASN B 40 13.121 -25.852 36.719 1.00 66.77 O +ATOM 2210 CB ASN B 40 15.728 -24.978 35.356 1.00 72.23 C +ATOM 2211 CG ASN B 40 16.668 -26.152 35.206 1.00113.40 C +ATOM 2212 OD1 ASN B 40 16.990 -26.592 34.098 1.00167.82 O +ATOM 2213 ND2 ASN B 40 17.163 -26.634 36.329 1.00154.03 N +ATOM 2214 N ILE B 41 13.543 -27.477 35.232 1.00 82.37 N +ATOM 2215 CA ILE B 41 13.063 -28.556 36.101 1.00 99.19 C +ATOM 2216 C ILE B 41 14.203 -29.559 36.336 1.00115.38 C +ATOM 2217 O ILE B 41 14.701 -30.185 35.394 1.00163.59 O +ATOM 2218 CB ILE B 41 11.850 -29.299 35.483 1.00 86.19 C +ATOM 2219 CG1 ILE B 41 10.556 -28.530 35.713 1.00 67.36 C +ATOM 2220 CG2 ILE B 41 11.681 -30.648 36.151 1.00 89.13 C +ATOM 2221 CD1 ILE B 41 10.426 -27.257 34.924 1.00 72.26 C +ATOM 2222 N GLN B 42 14.634 -29.696 37.583 1.00 94.36 N +ATOM 2223 CA GLN B 42 15.871 -30.423 37.886 1.00 94.80 C +ATOM 2224 C GLN B 42 15.631 -31.895 38.109 1.00 79.56 C +ATOM 2225 O GLN B 42 14.556 -32.293 38.527 1.00 84.78 O +ATOM 2226 CB GLN B 42 16.561 -29.845 39.129 1.00126.60 C +ATOM 2227 CG GLN B 42 17.073 -28.415 38.981 1.00166.94 C +ATOM 2228 CD GLN B 42 16.406 -27.455 39.976 1.00179.15 C +ATOM 2229 OE1 GLN B 42 16.917 -27.239 41.062 1.00164.19 O +ATOM 2230 NE2 GLN B 42 15.239 -26.923 39.614 1.00181.74 N +ATOM 2231 N ASP B 43 16.686 -32.675 37.922 1.00 73.75 N +ATOM 2232 CA ASP B 43 16.735 -34.049 38.367 1.00 81.35 C +ATOM 2233 C ASP B 43 17.040 -34.112 39.866 1.00 90.07 C +ATOM 2234 O ASP B 43 18.079 -34.644 40.273 1.00 86.77 O +ATOM 2235 CB ASP B 43 17.815 -34.814 37.595 1.00 98.41 C +ATOM 2236 CG ASP B 43 17.749 -36.332 37.826 1.00112.48 C +ATOM 2237 OD1 ASP B 43 16.651 -36.909 37.693 1.00 89.55 O +ATOM 2238 OD2 ASP B 43 18.795 -36.967 38.111 1.00127.13 O +ATOM 2239 N GLU B 44 16.101 -33.632 40.690 1.00116.54 N +ATOM 2240 CA GLU B 44 16.247 -33.621 42.165 1.00132.13 C +ATOM 2241 C GLU B 44 16.151 -35.049 42.783 1.00104.39 C +ATOM 2242 O GLU B 44 16.074 -35.203 44.015 1.00 92.42 O +ATOM 2243 CB GLU B 44 15.189 -32.699 42.820 1.00142.49 C +ATOM 2244 CG GLU B 44 15.571 -31.215 42.924 1.00120.12 C +ATOM 2245 CD GLU B 44 14.472 -30.321 43.545 1.00130.60 C +ATOM 2246 OE1 GLU B 44 13.847 -30.691 44.575 1.00152.36 O +ATOM 2247 OE2 GLU B 44 14.216 -29.222 43.005 1.00 94.75 O +ATOM 2248 N THR B 45 16.278 -36.066 41.925 1.00 80.70 N +ATOM 2249 CA THR B 45 16.114 -37.454 42.323 1.00 69.01 C +ATOM 2250 C THR B 45 17.258 -37.992 43.181 1.00 75.65 C +ATOM 2251 O THR B 45 17.016 -38.739 44.127 1.00 90.80 O +ATOM 2252 CB THR B 45 15.814 -38.386 41.106 1.00 58.88 C +ATOM 2253 OG1 THR B 45 15.320 -39.628 41.584 1.00 67.95 O +ATOM 2254 CG2 THR B 45 17.020 -38.655 40.246 1.00 53.55 C +ATOM 2255 N GLY B 46 18.499 -37.666 42.827 1.00 94.45 N +ATOM 2256 CA GLY B 46 19.671 -38.058 43.627 1.00103.19 C +ATOM 2257 C GLY B 46 20.246 -39.433 43.271 1.00117.31 C +ATOM 2258 O GLY B 46 20.960 -40.090 44.049 1.00 81.68 O +ATOM 2259 N GLN B 47 19.925 -39.902 42.086 1.00105.72 N +ATOM 2260 CA GLN B 47 20.048 -41.288 41.861 1.00 80.07 C +ATOM 2261 C GLN B 47 20.798 -41.553 40.582 1.00 72.81 C +ATOM 2262 O GLN B 47 20.579 -40.932 39.546 1.00 54.46 O +ATOM 2263 CB GLN B 47 18.681 -41.925 41.874 1.00 69.55 C +ATOM 2264 CG GLN B 47 18.050 -41.922 43.247 1.00 88.14 C +ATOM 2265 CD GLN B 47 18.975 -42.452 44.320 1.00124.16 C +ATOM 2266 OE1 GLN B 47 19.215 -43.647 44.409 1.00154.63 O +ATOM 2267 NE2 GLN B 47 19.468 -41.571 45.175 1.00167.37 N +ATOM 2268 N PHE B 48 21.688 -42.530 40.688 1.00 85.67 N +ATOM 2269 CA PHE B 48 22.465 -43.020 39.573 1.00 86.62 C +ATOM 2270 C PHE B 48 22.253 -44.528 39.397 1.00100.43 C +ATOM 2271 O PHE B 48 21.745 -45.241 40.272 1.00 84.15 O +ATOM 2272 CB PHE B 48 23.949 -42.746 39.802 1.00 77.54 C +ATOM 2273 CG PHE B 48 24.273 -41.327 39.823 1.00 67.19 C +ATOM 2274 CD1 PHE B 48 23.995 -40.583 40.957 1.00 77.82 C +ATOM 2275 CD2 PHE B 48 24.806 -40.729 38.730 1.00 58.39 C +ATOM 2276 CE1 PHE B 48 24.219 -39.234 40.984 1.00 90.97 C +ATOM 2277 CE2 PHE B 48 25.080 -39.389 38.759 1.00 75.48 C +ATOM 2278 CZ PHE B 48 24.777 -38.636 39.880 1.00 91.46 C +ATOM 2279 N LYS B 49 22.703 -45.009 38.252 1.00111.48 N +ATOM 2280 CA LYS B 49 22.548 -46.403 37.915 1.00 99.64 C +ATOM 2281 C LYS B 49 23.580 -47.229 38.677 1.00107.07 C +ATOM 2282 O LYS B 49 24.702 -46.772 38.930 1.00102.25 O +ATOM 2283 CB LYS B 49 22.675 -46.596 36.399 1.00105.58 C +ATOM 2284 CG LYS B 49 21.545 -45.920 35.628 1.00103.83 C +ATOM 2285 CD LYS B 49 21.453 -46.221 34.139 1.00 99.34 C +ATOM 2286 CE LYS B 49 20.157 -45.594 33.633 1.00 97.36 C +ATOM 2287 NZ LYS B 49 19.856 -45.828 32.199 1.00112.97 N +ATOM 2288 N PRO B 50 23.200 -48.461 39.036 1.00119.29 N +ATOM 2289 CA PRO B 50 24.088 -49.373 39.755 1.00117.27 C +ATOM 2290 C PRO B 50 25.081 -50.078 38.828 1.00 81.75 C +ATOM 2291 O PRO B 50 24.938 -50.003 37.595 1.00 71.84 O +ATOM 2292 CB PRO B 50 23.118 -50.382 40.368 1.00122.34 C +ATOM 2293 CG PRO B 50 21.949 -50.396 39.436 1.00114.94 C +ATOM 2294 CD PRO B 50 21.836 -49.007 38.882 1.00111.44 C +ATOM 2295 N TYR B 51 26.063 -50.748 39.422 1.00 51.97 N +ATOM 2296 CA TYR B 51 26.947 -51.566 38.652 1.00 50.19 C +ATOM 2297 C TYR B 51 26.114 -52.487 37.798 1.00 51.56 C +ATOM 2298 O TYR B 51 25.144 -53.079 38.288 1.00 39.18 O +ATOM 2299 CB TYR B 51 27.877 -52.387 39.553 1.00 60.80 C +ATOM 2300 CG TYR B 51 29.028 -53.006 38.766 1.00 71.10 C +ATOM 2301 CD1 TYR B 51 30.186 -52.279 38.535 1.00 93.23 C +ATOM 2302 CD2 TYR B 51 28.942 -54.282 38.212 1.00 74.76 C +ATOM 2303 CE1 TYR B 51 31.223 -52.775 37.763 1.00 95.72 C +ATOM 2304 CE2 TYR B 51 29.993 -54.810 37.454 1.00 79.61 C +ATOM 2305 CZ TYR B 51 31.123 -54.027 37.217 1.00101.41 C +ATOM 2306 OH TYR B 51 32.205 -54.475 36.486 1.00120.62 O +ATOM 2307 N PRO B 52 26.485 -52.655 36.506 1.00 63.44 N +ATOM 2308 CA PRO B 52 27.686 -52.208 35.804 1.00 64.77 C +ATOM 2309 C PRO B 52 27.607 -50.900 35.049 1.00 70.91 C +ATOM 2310 O PRO B 52 28.479 -50.645 34.212 1.00 62.81 O +ATOM 2311 CB PRO B 52 27.917 -53.321 34.789 1.00 78.32 C +ATOM 2312 CG PRO B 52 26.538 -53.755 34.420 1.00 87.40 C +ATOM 2313 CD PRO B 52 25.712 -53.609 35.679 1.00 81.20 C +ATOM 2314 N ALA B 53 26.650 -50.043 35.386 1.00 79.15 N +ATOM 2315 CA ALA B 53 26.601 -48.728 34.757 1.00 83.22 C +ATOM 2316 C ALA B 53 27.760 -47.872 35.200 1.00 76.07 C +ATOM 2317 O ALA B 53 28.450 -48.154 36.209 1.00 66.31 O +ATOM 2318 CB ALA B 53 25.329 -48.008 35.092 1.00100.16 C +ATOM 2319 N SER B 54 28.043 -46.854 34.392 1.00 64.69 N +ATOM 2320 CA SER B 54 29.043 -45.886 34.815 1.00 52.42 C +ATOM 2321 C SER B 54 28.549 -45.281 36.127 1.00 39.95 C +ATOM 2322 O SER B 54 27.379 -45.035 36.305 1.00 33.11 O +ATOM 2323 CB SER B 54 29.314 -44.811 33.749 1.00 46.62 C +ATOM 2324 OG SER B 54 29.858 -43.616 34.321 1.00 35.45 O +ATOM 2325 N ASN B 55 29.502 -45.029 37.009 1.00 39.62 N +ATOM 2326 CA ASN B 55 29.286 -44.317 38.238 1.00 38.18 C +ATOM 2327 C ASN B 55 28.474 -43.056 38.038 1.00 40.14 C +ATOM 2328 O ASN B 55 27.674 -42.647 38.886 1.00 40.31 O +ATOM 2329 CB ASN B 55 30.651 -43.954 38.817 1.00 39.10 C +ATOM 2330 CG ASN B 55 30.565 -43.547 40.236 1.00 61.24 C +ATOM 2331 OD1 ASN B 55 29.583 -43.826 40.947 1.00108.68 O +ATOM 2332 ND2 ASN B 55 31.644 -42.986 40.717 1.00 72.45 N +ATOM 2333 N PHE B 56 28.629 -42.463 36.855 1.00 48.43 N +ATOM 2334 CA PHE B 56 28.074 -41.145 36.556 1.00 55.79 C +ATOM 2335 C PHE B 56 26.764 -41.200 35.785 1.00 68.64 C +ATOM 2336 O PHE B 56 26.235 -40.156 35.374 1.00 72.53 O +ATOM 2337 CB PHE B 56 29.047 -40.339 35.715 1.00 57.79 C +ATOM 2338 CG PHE B 56 30.383 -40.147 36.358 1.00 59.19 C +ATOM 2339 CD1 PHE B 56 30.521 -39.515 37.591 1.00 46.05 C +ATOM 2340 CD2 PHE B 56 31.507 -40.597 35.712 1.00 81.20 C +ATOM 2341 CE1 PHE B 56 31.750 -39.368 38.180 1.00 47.02 C +ATOM 2342 CE2 PHE B 56 32.756 -40.410 36.281 1.00 82.67 C +ATOM 2343 CZ PHE B 56 32.875 -39.795 37.518 1.00 61.56 C +ATOM 2344 N SER B 57 26.281 -42.400 35.478 1.00 69.37 N +ATOM 2345 CA SER B 57 25.057 -42.508 34.681 1.00 71.80 C +ATOM 2346 C SER B 57 23.885 -42.226 35.614 1.00 77.94 C +ATOM 2347 O SER B 57 23.632 -42.964 36.557 1.00 58.31 O +ATOM 2348 CB SER B 57 24.931 -43.886 34.008 1.00 68.01 C +ATOM 2349 OG SER B 57 25.808 -43.970 32.897 1.00 66.21 O +ATOM 2350 N THR B 58 23.153 -41.155 35.322 1.00 83.38 N +ATOM 2351 CA THR B 58 22.006 -40.785 36.132 1.00 65.42 C +ATOM 2352 C THR B 58 20.849 -41.723 35.883 1.00 74.15 C +ATOM 2353 O THR B 58 20.696 -42.316 34.821 1.00 48.84 O +ATOM 2354 CB THR B 58 21.506 -39.402 35.771 1.00 49.67 C +ATOM 2355 OG1 THR B 58 21.105 -39.379 34.401 1.00 41.19 O +ATOM 2356 CG2 THR B 58 22.582 -38.438 35.963 1.00 50.87 C +ATOM 2357 N ALA B 59 20.016 -41.887 36.879 1.00 80.35 N +ATOM 2358 CA ALA B 59 18.968 -42.863 36.717 1.00 87.46 C +ATOM 2359 C ALA B 59 17.863 -42.298 35.837 1.00 82.21 C +ATOM 2360 O ALA B 59 17.044 -43.034 35.296 1.00 90.41 O +ATOM 2361 CB ALA B 59 18.432 -43.282 38.063 1.00103.39 C +ATOM 2362 N VAL B 60 17.821 -40.974 35.739 1.00 84.61 N +ATOM 2363 CA VAL B 60 16.725 -40.266 35.082 1.00 82.36 C +ATOM 2364 C VAL B 60 17.327 -39.246 34.113 1.00 85.74 C +ATOM 2365 O VAL B 60 18.324 -38.598 34.424 1.00 87.30 O +ATOM 2366 CB VAL B 60 15.878 -39.522 36.131 1.00 74.12 C +ATOM 2367 CG1 VAL B 60 14.745 -38.755 35.480 1.00 79.67 C +ATOM 2368 CG2 VAL B 60 15.339 -40.496 37.143 1.00 89.32 C +ATOM 2369 N PRO B 61 16.743 -39.126 32.917 1.00 82.74 N +ATOM 2370 CA PRO B 61 17.293 -38.149 31.997 1.00 80.67 C +ATOM 2371 C PRO B 61 17.214 -36.734 32.545 1.00 75.98 C +ATOM 2372 O PRO B 61 16.171 -36.354 33.153 1.00112.84 O +ATOM 2373 CB PRO B 61 16.412 -38.329 30.734 1.00 94.69 C +ATOM 2374 CG PRO B 61 15.152 -38.994 31.205 1.00 73.79 C +ATOM 2375 CD PRO B 61 15.602 -39.869 32.338 1.00 74.65 C +ATOM 2376 N GLN B 62 18.214 -35.927 32.190 1.00 66.78 N +ATOM 2377 CA GLN B 62 18.272 -34.532 32.628 1.00 68.19 C +ATOM 2378 C GLN B 62 17.539 -33.607 31.680 1.00 63.15 C +ATOM 2379 O GLN B 62 17.915 -32.463 31.521 1.00 41.22 O +ATOM 2380 CB GLN B 62 19.716 -34.078 32.690 1.00 92.23 C +ATOM 2381 CG GLN B 62 20.627 -35.043 33.427 1.00116.78 C +ATOM 2382 CD GLN B 62 20.165 -35.276 34.853 1.00127.79 C +ATOM 2383 OE1 GLN B 62 20.391 -34.454 35.735 1.00117.31 O +ATOM 2384 NE2 GLN B 62 19.498 -36.389 35.078 1.00141.56 N +ATOM 2385 N SER B 63 16.404 -34.074 31.139 1.00 93.40 N +ATOM 2386 CA SER B 63 15.740 -33.426 29.990 1.00 73.23 C +ATOM 2387 C SER B 63 14.285 -33.057 30.292 1.00 77.42 C +ATOM 2388 O SER B 63 13.587 -32.529 29.428 1.00 87.58 O +ATOM 2389 CB SER B 63 15.790 -34.356 28.778 1.00 48.40 C +ATOM 2390 OG SER B 63 15.078 -35.539 29.027 1.00 31.71 O +ATOM 2391 N ALA B 64 13.904 -33.149 31.566 1.00 90.14 N +ATOM 2392 CA ALA B 64 12.552 -32.819 31.999 1.00102.66 C +ATOM 2393 C ALA B 64 12.027 -31.427 31.556 1.00142.69 C +ATOM 2394 O ALA B 64 10.851 -31.274 31.170 1.00151.97 O +ATOM 2395 CB ALA B 64 12.457 -32.942 33.511 1.00112.11 C +ATOM 2396 N THR B 65 12.889 -30.414 31.649 1.00132.10 N +ATOM 2397 CA THR B 65 12.537 -29.035 31.302 1.00 98.00 C +ATOM 2398 C THR B 65 11.940 -28.935 29.907 1.00102.04 C +ATOM 2399 O THR B 65 10.875 -28.350 29.714 1.00101.24 O +ATOM 2400 CB THR B 65 13.790 -28.174 31.305 1.00 84.22 C +ATOM 2401 OG1 THR B 65 14.610 -28.572 32.405 1.00 89.47 O +ATOM 2402 CG2 THR B 65 13.433 -26.701 31.405 1.00 83.84 C +ATOM 2403 N ALA B 66 12.622 -29.539 28.941 1.00105.90 N +ATOM 2404 CA ALA B 66 12.176 -29.476 27.572 1.00100.25 C +ATOM 2405 C ALA B 66 10.877 -30.285 27.345 1.00 73.95 C +ATOM 2406 O ALA B 66 10.018 -29.875 26.550 1.00 52.65 O +ATOM 2407 CB ALA B 66 13.286 -29.951 26.657 1.00122.04 C +ATOM 2408 N MET B 67 10.750 -31.401 28.062 1.00 55.66 N +ATOM 2409 CA MET B 67 9.564 -32.220 27.983 1.00 61.77 C +ATOM 2410 C MET B 67 8.378 -31.424 28.515 1.00 71.61 C +ATOM 2411 O MET B 67 7.257 -31.469 27.920 1.00109.16 O +ATOM 2412 CB MET B 67 9.709 -33.492 28.805 1.00 65.60 C +ATOM 2413 CG MET B 67 10.670 -34.536 28.242 1.00 56.21 C +ATOM 2414 SD MET B 67 11.013 -35.824 29.491 1.00 80.87 S +ATOM 2415 CE MET B 67 11.980 -36.978 28.533 1.00 64.11 C +ATOM 2416 N LEU B 68 8.596 -30.679 29.606 1.00 48.55 N +ATOM 2417 CA LEU B 68 7.512 -29.881 30.156 1.00 60.61 C +ATOM 2418 C LEU B 68 7.076 -28.776 29.176 1.00 76.25 C +ATOM 2419 O LEU B 68 5.869 -28.549 28.991 1.00100.75 O +ATOM 2420 CB LEU B 68 7.883 -29.241 31.475 1.00 54.47 C +ATOM 2421 CG LEU B 68 6.850 -28.201 31.985 1.00 58.53 C +ATOM 2422 CD1 LEU B 68 5.513 -28.870 32.347 1.00 55.82 C +ATOM 2423 CD2 LEU B 68 7.368 -27.393 33.171 1.00 53.68 C +ATOM 2424 N VAL B 69 8.038 -28.087 28.575 1.00 70.48 N +ATOM 2425 CA VAL B 69 7.731 -27.005 27.635 1.00 55.09 C +ATOM 2426 C VAL B 69 6.997 -27.554 26.453 1.00 49.96 C +ATOM 2427 O VAL B 69 5.953 -27.005 26.037 1.00 75.22 O +ATOM 2428 CB VAL B 69 8.990 -26.329 27.095 1.00 67.91 C +ATOM 2429 CG1 VAL B 69 8.633 -25.374 25.985 1.00 56.09 C +ATOM 2430 CG2 VAL B 69 9.744 -25.576 28.205 1.00 80.01 C +ATOM 2431 N THR B 70 7.462 -28.688 25.959 1.00 47.46 N +ATOM 2432 CA THR B 70 6.723 -29.394 24.902 1.00 76.76 C +ATOM 2433 C THR B 70 5.264 -29.838 25.243 1.00 56.94 C +ATOM 2434 O THR B 70 4.329 -29.585 24.475 1.00 42.47 O +ATOM 2435 CB THR B 70 7.505 -30.626 24.445 1.00109.26 C +ATOM 2436 OG1 THR B 70 8.843 -30.219 24.120 1.00103.39 O +ATOM 2437 CG2 THR B 70 6.833 -31.287 23.205 1.00118.43 C +ATOM 2438 N ALA B 71 5.084 -30.422 26.416 1.00 46.53 N +ATOM 2439 CA ALA B 71 3.752 -30.744 26.895 1.00 47.43 C +ATOM 2440 C ALA B 71 2.854 -29.517 27.075 1.00 48.97 C +ATOM 2441 O ALA B 71 1.681 -29.525 26.660 1.00 56.36 O +ATOM 2442 CB ALA B 71 3.842 -31.477 28.209 1.00 58.74 C +ATOM 2443 N LEU B 72 3.406 -28.452 27.650 1.00 55.18 N +ATOM 2444 CA LEU B 72 2.690 -27.158 27.714 1.00 67.16 C +ATOM 2445 C LEU B 72 2.286 -26.586 26.350 1.00 73.74 C +ATOM 2446 O LEU B 72 1.260 -25.911 26.237 1.00 88.87 O +ATOM 2447 CB LEU B 72 3.529 -26.090 28.403 1.00 61.96 C +ATOM 2448 CG LEU B 72 3.812 -26.371 29.860 1.00 61.05 C +ATOM 2449 CD1 LEU B 72 4.956 -25.506 30.306 1.00 62.89 C +ATOM 2450 CD2 LEU B 72 2.602 -26.108 30.725 1.00 85.42 C +ATOM 2451 N LYS B 73 3.043 -26.912 25.309 1.00 73.20 N +ATOM 2452 CA LYS B 73 2.659 -26.508 23.974 1.00 92.49 C +ATOM 2453 C LYS B 73 1.597 -27.417 23.332 1.00108.79 C +ATOM 2454 O LYS B 73 0.641 -26.923 22.718 1.00108.93 O +ATOM 2455 CB LYS B 73 3.873 -26.467 23.068 1.00 92.80 C +ATOM 2456 CG LYS B 73 3.596 -25.779 21.750 1.00111.20 C +ATOM 2457 CD LYS B 73 4.532 -26.299 20.693 1.00 99.31 C +ATOM 2458 CE LYS B 73 4.102 -27.657 20.091 1.00105.52 C +ATOM 2459 NZ LYS B 73 3.516 -27.515 18.724 1.00106.01 N +ATOM 2460 N ASP B 74 1.800 -28.736 23.421 1.00107.56 N +ATOM 2461 CA ASP B 74 0.903 -29.715 22.787 1.00101.59 C +ATOM 2462 C ASP B 74 -0.524 -29.617 23.327 1.00113.16 C +ATOM 2463 O ASP B 74 -1.481 -29.881 22.594 1.00149.64 O +ATOM 2464 CB ASP B 74 1.405 -31.134 23.006 1.00111.01 C +ATOM 2465 CG ASP B 74 2.700 -31.429 22.255 1.00145.25 C +ATOM 2466 OD1 ASP B 74 2.959 -30.831 21.176 1.00168.99 O +ATOM 2467 OD2 ASP B 74 3.456 -32.306 22.741 1.00163.35 O +ATOM 2468 N SER B 75 -0.666 -29.150 24.573 1.00110.05 N +ATOM 2469 CA SER B 75 -1.984 -28.988 25.219 1.00 92.43 C +ATOM 2470 C SER B 75 -2.873 -27.948 24.546 1.00 90.25 C +ATOM 2471 O SER B 75 -4.105 -28.028 24.610 1.00 93.53 O +ATOM 2472 CB SER B 75 -1.822 -28.579 26.678 1.00 86.28 C +ATOM 2473 OG SER B 75 -1.710 -27.170 26.816 1.00 63.32 O +ATOM 2474 N ARG B 76 -2.240 -26.976 23.895 1.00 90.79 N +ATOM 2475 CA ARG B 76 -2.943 -25.922 23.182 1.00101.41 C +ATOM 2476 C ARG B 76 -3.683 -25.017 24.156 1.00 85.57 C +ATOM 2477 O ARG B 76 -4.776 -24.502 23.886 1.00151.92 O +ATOM 2478 CB ARG B 76 -3.824 -26.493 22.048 1.00119.10 C +ATOM 2479 CG ARG B 76 -3.181 -26.313 20.664 1.00138.64 C +ATOM 2480 CD ARG B 76 -4.206 -25.861 19.639 1.00175.90 C +ATOM 2481 NE ARG B 76 -4.549 -24.427 19.624 1.00167.41 N +ATOM 2482 CZ ARG B 76 -4.425 -23.581 18.597 1.00126.04 C +ATOM 2483 NH1 ARG B 76 -3.930 -23.949 17.408 1.00 91.39 N +ATOM 2484 NH2 ARG B 76 -4.808 -22.324 18.776 1.00123.77 N +ATOM 2485 N TRP B 77 -3.072 -24.858 25.314 1.00 65.83 N +ATOM 2486 CA TRP B 77 -3.537 -23.925 26.316 1.00 81.75 C +ATOM 2487 C TRP B 77 -2.504 -22.818 26.537 1.00 90.74 C +ATOM 2488 O TRP B 77 -2.862 -21.673 26.816 1.00100.98 O +ATOM 2489 CB TRP B 77 -3.780 -24.671 27.630 1.00 92.07 C +ATOM 2490 CG TRP B 77 -5.181 -25.145 27.809 1.00101.75 C +ATOM 2491 CD1 TRP B 77 -5.759 -26.220 27.215 1.00105.41 C +ATOM 2492 CD2 TRP B 77 -6.185 -24.567 28.660 1.00112.59 C +ATOM 2493 NE1 TRP B 77 -7.069 -26.340 27.621 1.00101.28 N +ATOM 2494 CE2 TRP B 77 -7.355 -25.329 28.501 1.00 99.97 C +ATOM 2495 CE3 TRP B 77 -6.205 -23.473 29.538 1.00116.47 C +ATOM 2496 CZ2 TRP B 77 -8.527 -25.042 29.190 1.00100.66 C +ATOM 2497 CZ3 TRP B 77 -7.369 -23.195 30.226 1.00101.62 C +ATOM 2498 CH2 TRP B 77 -8.513 -23.980 30.051 1.00103.54 C +ATOM 2499 N PHE B 78 -1.226 -23.167 26.372 1.00105.95 N +ATOM 2500 CA PHE B 78 -0.090 -22.282 26.694 1.00 86.31 C +ATOM 2501 C PHE B 78 0.852 -22.026 25.509 1.00 75.73 C +ATOM 2502 O PHE B 78 1.074 -22.926 24.670 1.00 67.06 O +ATOM 2503 CB PHE B 78 0.768 -22.908 27.775 1.00 79.47 C +ATOM 2504 CG PHE B 78 0.022 -23.274 29.012 1.00 83.55 C +ATOM 2505 CD1 PHE B 78 -0.365 -22.305 29.915 1.00 96.89 C +ATOM 2506 CD2 PHE B 78 -0.227 -24.595 29.307 1.00 82.50 C +ATOM 2507 CE1 PHE B 78 -1.014 -22.647 31.083 1.00102.38 C +ATOM 2508 CE2 PHE B 78 -0.892 -24.945 30.464 1.00 94.12 C +ATOM 2509 CZ PHE B 78 -1.275 -23.972 31.362 1.00 94.35 C +ATOM 2510 N ILE B 79 1.358 -20.792 25.431 1.00 64.27 N +ATOM 2511 CA ILE B 79 2.455 -20.438 24.543 1.00 73.30 C +ATOM 2512 C ILE B 79 3.689 -20.418 25.420 1.00 86.30 C +ATOM 2513 O ILE B 79 3.662 -19.743 26.457 1.00 89.89 O +ATOM 2514 CB ILE B 79 2.296 -19.037 23.949 1.00 76.03 C +ATOM 2515 CG1 ILE B 79 0.921 -18.867 23.298 1.00 97.72 C +ATOM 2516 CG2 ILE B 79 3.382 -18.766 22.913 1.00 80.42 C +ATOM 2517 CD1 ILE B 79 0.482 -17.411 23.190 1.00126.95 C +ATOM 2518 N PRO B 80 4.731 -21.222 25.057 1.00 74.83 N +ATOM 2519 CA PRO B 80 5.875 -21.205 25.931 1.00 54.05 C +ATOM 2520 C PRO B 80 6.870 -20.220 25.443 1.00 53.96 C +ATOM 2521 O PRO B 80 7.065 -20.107 24.239 1.00 82.14 O +ATOM 2522 CB PRO B 80 6.424 -22.596 25.798 1.00 51.13 C +ATOM 2523 CG PRO B 80 5.268 -23.435 25.400 1.00 60.13 C +ATOM 2524 CD PRO B 80 4.564 -22.551 24.436 1.00 66.94 C +ATOM 2525 N LEU B 81 7.322 -19.370 26.347 1.00 42.70 N +ATOM 2526 CA LEU B 81 8.327 -18.443 26.019 1.00 41.49 C +ATOM 2527 C LEU B 81 9.647 -19.088 26.338 1.00 66.74 C +ATOM 2528 O LEU B 81 9.796 -19.809 27.363 1.00 47.38 O +ATOM 2529 CB LEU B 81 8.136 -17.182 26.797 1.00 41.18 C +ATOM 2530 CG LEU B 81 6.763 -16.611 26.541 1.00 42.57 C +ATOM 2531 CD1 LEU B 81 6.555 -15.390 27.429 1.00 55.65 C +ATOM 2532 CD2 LEU B 81 6.616 -16.214 25.101 1.00 42.24 C +ATOM 2533 N GLU B 82 10.621 -18.823 25.448 1.00122.90 N +ATOM 2534 CA GLU B 82 11.974 -19.406 25.536 1.00126.30 C +ATOM 2535 C GLU B 82 12.854 -18.725 26.600 1.00 87.59 C +ATOM 2536 O GLU B 82 13.292 -17.591 26.422 1.00 40.50 O +ATOM 2537 CB GLU B 82 12.693 -19.415 24.170 1.00 89.98 C +ATOM 2538 CG GLU B 82 14.080 -20.044 24.208 1.00102.28 C +ATOM 2539 CD GLU B 82 14.088 -21.583 24.424 1.00125.38 C +ATOM 2540 OE1 GLU B 82 13.447 -22.131 25.372 1.00127.03 O +ATOM 2541 OE2 GLU B 82 14.836 -22.274 23.686 1.00138.80 O +ATOM 2542 N ARG B 83 13.057 -19.457 27.707 1.00 77.36 N +ATOM 2543 CA ARG B 83 13.938 -19.046 28.763 1.00 75.58 C +ATOM 2544 C ARG B 83 15.045 -20.065 29.067 1.00 77.59 C +ATOM 2545 O ARG B 83 16.087 -19.698 29.628 1.00 57.83 O +ATOM 2546 CB ARG B 83 13.142 -18.756 30.028 1.00 85.28 C +ATOM 2547 CG ARG B 83 12.038 -17.712 29.841 1.00 84.62 C +ATOM 2548 CD ARG B 83 12.587 -16.297 29.586 1.00 68.02 C +ATOM 2549 NE ARG B 83 11.531 -15.320 29.685 1.00 68.59 N +ATOM 2550 CZ ARG B 83 10.840 -14.845 28.662 1.00 89.26 C +ATOM 2551 NH1 ARG B 83 11.221 -15.080 27.418 1.00 91.39 N +ATOM 2552 NH2 ARG B 83 9.760 -14.099 28.897 1.00119.27 N +ATOM 2553 N GLN B 84 14.884 -21.315 28.651 1.00 85.28 N +ATOM 2554 CA GLN B 84 15.972 -22.265 28.896 1.00 92.73 C +ATOM 2555 C GLN B 84 17.247 -21.766 28.216 1.00 80.00 C +ATOM 2556 O GLN B 84 18.328 -21.865 28.771 1.00 91.49 O +ATOM 2557 CB GLN B 84 15.613 -23.699 28.467 1.00104.90 C +ATOM 2558 CG GLN B 84 16.275 -24.800 29.312 1.00 92.52 C +ATOM 2559 CD GLN B 84 15.961 -26.206 28.805 1.00134.72 C +ATOM 2560 OE1 GLN B 84 14.870 -26.471 28.302 1.00155.94 O +ATOM 2561 NE2 GLN B 84 16.942 -27.099 28.889 1.00163.68 N +ATOM 2562 N GLY B 85 17.138 -21.251 27.003 1.00 64.74 N +ATOM 2563 CA GLY B 85 18.331 -20.780 26.323 1.00 74.10 C +ATOM 2564 C GLY B 85 18.405 -19.270 26.223 1.00 70.15 C +ATOM 2565 O GLY B 85 18.764 -18.733 25.165 1.00 62.26 O +ATOM 2566 N LEU B 86 18.053 -18.575 27.300 1.00 65.43 N +ATOM 2567 CA LEU B 86 17.731 -17.131 27.198 1.00 64.99 C +ATOM 2568 C LEU B 86 18.958 -16.366 26.776 1.00 85.75 C +ATOM 2569 O LEU B 86 18.869 -15.377 26.040 1.00110.54 O +ATOM 2570 CB LEU B 86 17.210 -16.602 28.538 1.00 47.23 C +ATOM 2571 CG LEU B 86 17.035 -15.115 28.727 1.00 41.27 C +ATOM 2572 CD1 LEU B 86 16.054 -14.481 27.754 1.00 34.51 C +ATOM 2573 CD2 LEU B 86 16.584 -14.843 30.154 1.00 54.52 C +ATOM 2574 N GLN B 87 20.118 -16.857 27.199 1.00103.60 N +ATOM 2575 CA GLN B 87 21.365 -16.141 26.947 1.00112.47 C +ATOM 2576 C GLN B 87 21.645 -15.996 25.429 1.00115.51 C +ATOM 2577 O GLN B 87 22.020 -14.920 24.929 1.00 90.52 O +ATOM 2578 CB GLN B 87 22.516 -16.835 27.682 1.00112.50 C +ATOM 2579 CG GLN B 87 23.586 -15.873 28.181 1.00111.95 C +ATOM 2580 CD GLN B 87 23.000 -14.606 28.800 1.00116.51 C +ATOM 2581 OE1 GLN B 87 22.240 -14.667 29.778 1.00145.42 O +ATOM 2582 NE2 GLN B 87 23.383 -13.446 28.266 1.00105.29 N +ATOM 2583 N ASN B 88 21.408 -17.078 24.696 1.00 99.71 N +ATOM 2584 CA ASN B 88 21.603 -17.085 23.254 1.00 96.31 C +ATOM 2585 C ASN B 88 20.620 -16.178 22.539 1.00100.27 C +ATOM 2586 O ASN B 88 20.964 -15.541 21.523 1.00155.39 O +ATOM 2587 CB ASN B 88 21.404 -18.492 22.711 1.00 89.05 C +ATOM 2588 CG ASN B 88 22.310 -19.491 23.372 1.00 72.53 C +ATOM 2589 OD1 ASN B 88 23.466 -19.186 23.651 1.00 59.37 O +ATOM 2590 ND2 ASN B 88 21.797 -20.698 23.612 1.00 72.08 N +ATOM 2591 N LEU B 89 19.397 -16.155 23.047 1.00 65.82 N +ATOM 2592 CA LEU B 89 18.385 -15.309 22.494 1.00 72.18 C +ATOM 2593 C LEU B 89 18.803 -13.831 22.601 1.00 83.78 C +ATOM 2594 O LEU B 89 18.713 -13.045 21.641 1.00124.19 O +ATOM 2595 CB LEU B 89 17.101 -15.550 23.263 1.00 85.91 C +ATOM 2596 CG LEU B 89 15.760 -15.364 22.535 1.00 79.58 C +ATOM 2597 CD1 LEU B 89 14.976 -14.240 23.171 1.00 65.49 C +ATOM 2598 CD2 LEU B 89 15.933 -15.112 21.043 1.00 54.98 C +ATOM 2599 N LEU B 90 19.372 -13.474 23.743 1.00 74.74 N +ATOM 2600 CA LEU B 90 19.796 -12.099 23.977 1.00 64.68 C +ATOM 2601 C LEU B 90 21.019 -11.739 23.126 1.00 84.94 C +ATOM 2602 O LEU B 90 21.205 -10.576 22.716 1.00108.92 O +ATOM 2603 CB LEU B 90 20.114 -11.897 25.451 1.00 47.33 C +ATOM 2604 CG LEU B 90 18.945 -12.137 26.385 1.00 38.74 C +ATOM 2605 CD1 LEU B 90 19.462 -12.363 27.791 1.00 45.38 C +ATOM 2606 CD2 LEU B 90 17.991 -10.979 26.337 1.00 35.70 C +ATOM 2607 N ASN B 91 21.848 -12.742 22.870 1.00 93.45 N +ATOM 2608 CA ASN B 91 23.015 -12.566 22.031 1.00102.50 C +ATOM 2609 C ASN B 91 22.631 -12.292 20.581 1.00 93.07 C +ATOM 2610 O ASN B 91 23.140 -11.352 19.954 1.00108.35 O +ATOM 2611 CB ASN B 91 23.866 -13.825 22.113 1.00108.31 C +ATOM 2612 CG ASN B 91 25.230 -13.590 22.673 1.00139.61 C +ATOM 2613 OD1 ASN B 91 25.485 -12.630 23.425 1.00124.46 O +ATOM 2614 ND2 ASN B 91 26.124 -14.513 22.347 1.00174.91 N +ATOM 2615 N GLU B 92 21.745 -13.115 20.032 1.00 80.42 N +ATOM 2616 CA GLU B 92 21.252 -12.875 18.667 1.00 75.59 C +ATOM 2617 C GLU B 92 20.654 -11.469 18.547 1.00 63.85 C +ATOM 2618 O GLU B 92 20.758 -10.825 17.495 1.00 46.92 O +ATOM 2619 CB GLU B 92 20.225 -13.943 18.238 1.00 72.58 C +ATOM 2620 CG GLU B 92 20.843 -15.126 17.520 1.00 84.07 C +ATOM 2621 CD GLU B 92 21.723 -14.718 16.315 1.00 84.33 C +ATOM 2622 OE1 GLU B 92 21.245 -14.069 15.359 1.00 66.69 O +ATOM 2623 OE2 GLU B 92 22.903 -15.124 16.273 1.00 71.48 O +ATOM 2624 N ARG B 93 19.996 -11.017 19.613 1.00 59.11 N +ATOM 2625 CA ARG B 93 19.353 -9.719 19.590 1.00 70.63 C +ATOM 2626 C ARG B 93 20.414 -8.624 19.608 1.00 97.52 C +ATOM 2627 O ARG B 93 20.246 -7.577 18.974 1.00120.68 O +ATOM 2628 CB ARG B 93 18.344 -9.610 20.730 1.00 67.07 C +ATOM 2629 CG ARG B 93 17.131 -10.490 20.477 1.00113.48 C +ATOM 2630 CD ARG B 93 16.246 -10.708 21.688 1.00140.47 C +ATOM 2631 NE ARG B 93 15.062 -9.857 21.645 1.00128.34 N +ATOM 2632 CZ ARG B 93 14.968 -8.672 22.226 1.00119.65 C +ATOM 2633 NH1 ARG B 93 15.960 -8.183 22.983 1.00105.37 N +ATOM 2634 NH2 ARG B 93 13.829 -8.016 22.108 1.00109.16 N +ATOM 2635 N LYS B 94 21.544 -8.887 20.270 1.00 93.53 N +ATOM 2636 CA LYS B 94 22.666 -7.941 20.240 1.00 76.60 C +ATOM 2637 C LYS B 94 23.202 -7.827 18.819 1.00 79.42 C +ATOM 2638 O LYS B 94 23.517 -6.727 18.349 1.00 81.46 O +ATOM 2639 CB LYS B 94 23.788 -8.408 21.147 1.00 81.09 C +ATOM 2640 CG LYS B 94 23.703 -7.948 22.591 1.00109.83 C +ATOM 2641 CD LYS B 94 24.776 -8.642 23.424 1.00123.52 C +ATOM 2642 CE LYS B 94 25.087 -7.911 24.723 1.00110.85 C +ATOM 2643 NZ LYS B 94 25.861 -8.798 25.635 1.00110.43 N +ATOM 2644 N ILE B 95 23.271 -8.962 18.122 1.00 83.29 N +ATOM 2645 CA ILE B 95 23.873 -8.987 16.785 1.00 84.66 C +ATOM 2646 C ILE B 95 22.968 -8.331 15.770 1.00 82.07 C +ATOM 2647 O ILE B 95 23.461 -7.602 14.878 1.00 74.88 O +ATOM 2648 CB ILE B 95 24.175 -10.401 16.271 1.00 89.18 C +ATOM 2649 CG1 ILE B 95 24.924 -11.226 17.326 1.00 94.86 C +ATOM 2650 CG2 ILE B 95 25.043 -10.283 15.038 1.00 95.24 C +ATOM 2651 CD1 ILE B 95 25.544 -12.509 16.807 1.00 91.36 C +ATOM 2652 N ILE B 96 21.656 -8.588 15.928 1.00 65.25 N +ATOM 2653 CA ILE B 96 20.628 -7.901 15.153 1.00 53.31 C +ATOM 2654 C ILE B 96 20.753 -6.400 15.315 1.00 67.76 C +ATOM 2655 O ILE B 96 20.997 -5.680 14.341 1.00 92.06 O +ATOM 2656 CB ILE B 96 19.233 -8.283 15.566 1.00 38.03 C +ATOM 2657 CG1 ILE B 96 18.957 -9.719 15.206 1.00 37.83 C +ATOM 2658 CG2 ILE B 96 18.248 -7.429 14.818 1.00 35.78 C +ATOM 2659 CD1 ILE B 96 17.538 -10.175 15.517 1.00 40.48 C +ATOM 2660 N ARG B 97 20.671 -5.921 16.555 1.00 67.57 N +ATOM 2661 CA ARG B 97 20.741 -4.470 16.818 1.00 82.25 C +ATOM 2662 C ARG B 97 22.054 -3.823 16.316 1.00 83.29 C +ATOM 2663 O ARG B 97 22.071 -2.662 15.902 1.00 70.86 O +ATOM 2664 CB ARG B 97 20.563 -4.164 18.313 1.00 99.34 C +ATOM 2665 CG ARG B 97 19.169 -3.661 18.702 1.00 82.88 C +ATOM 2666 CD ARG B 97 19.110 -3.326 20.183 1.00 86.40 C +ATOM 2667 NE ARG B 97 18.930 -4.515 21.015 1.00 83.26 N +ATOM 2668 CZ ARG B 97 17.762 -4.927 21.504 1.00102.33 C +ATOM 2669 NH1 ARG B 97 16.647 -4.228 21.285 1.00 74.15 N +ATOM 2670 NH2 ARG B 97 17.715 -6.056 22.227 1.00128.16 N +ATOM 2671 N ALA B 98 23.139 -4.585 16.335 1.00 80.11 N +ATOM 2672 CA ALA B 98 24.404 -4.086 15.851 1.00 81.74 C +ATOM 2673 C ALA B 98 24.408 -4.039 14.328 1.00 88.00 C +ATOM 2674 O ALA B 98 25.117 -3.223 13.722 1.00 65.22 O +ATOM 2675 CB ALA B 98 25.521 -4.968 16.370 1.00103.21 C +ATOM 2676 N ALA B 99 23.619 -4.930 13.717 1.00111.36 N +ATOM 2677 CA ALA B 99 23.521 -5.035 12.251 1.00124.51 C +ATOM 2678 C ALA B 99 22.813 -3.848 11.634 1.00103.92 C +ATOM 2679 O ALA B 99 23.320 -3.207 10.715 1.00117.54 O +ATOM 2680 CB ALA B 99 22.797 -6.309 11.849 1.00121.16 C +ATOM 2681 N GLN B 100 21.656 -3.526 12.187 1.00109.12 N +ATOM 2682 CA GLN B 100 20.726 -2.619 11.520 1.00120.00 C +ATOM 2683 C GLN B 100 20.644 -1.231 12.147 1.00 89.51 C +ATOM 2684 O GLN B 100 19.822 -0.407 11.724 1.00121.87 O +ATOM 2685 CB GLN B 100 19.325 -3.245 11.439 1.00117.87 C +ATOM 2686 CG GLN B 100 18.863 -3.925 12.711 1.00 96.10 C +ATOM 2687 CD GLN B 100 17.884 -5.040 12.459 1.00 86.11 C +ATOM 2688 OE1 GLN B 100 18.160 -6.035 11.753 1.00 70.75 O +ATOM 2689 NE2 GLN B 100 16.704 -4.881 13.037 1.00 96.98 N +ATOM 2690 N GLU B 101 21.523 -0.945 13.098 1.00 70.61 N +ATOM 2691 CA GLU B 101 21.500 0.359 13.771 1.00 86.24 C +ATOM 2692 C GLU B 101 21.883 1.521 12.846 1.00 83.45 C +ATOM 2693 O GLU B 101 21.521 2.668 13.098 1.00 82.52 O +ATOM 2694 CB GLU B 101 22.389 0.349 15.020 1.00 86.56 C +ATOM 2695 CG GLU B 101 23.809 -0.124 14.779 1.00103.91 C +ATOM 2696 CD GLU B 101 24.679 -0.021 16.026 1.00100.21 C +ATOM 2697 OE1 GLU B 101 24.111 0.056 17.128 1.00102.49 O +ATOM 2698 OE2 GLU B 101 25.928 -0.085 15.903 1.00 85.89 O +ATOM 2699 N ASN B 102 22.616 1.226 11.782 1.00 90.03 N +ATOM 2700 CA ASN B 102 23.086 2.266 10.884 1.00 95.81 C +ATOM 2701 C ASN B 102 22.165 2.510 9.710 1.00 91.15 C +ATOM 2702 O ASN B 102 22.421 3.389 8.885 1.00 90.05 O +ATOM 2703 CB ASN B 102 24.482 1.926 10.376 1.00101.83 C +ATOM 2704 CG ASN B 102 25.529 2.076 11.456 1.00103.69 C +ATOM 2705 OD1 ASN B 102 25.964 3.197 11.785 1.00103.07 O +ATOM 2706 ND2 ASN B 102 25.924 0.953 12.036 1.00 93.23 N +ATOM 2707 N GLY B 103 21.097 1.732 9.619 1.00100.74 N +ATOM 2708 CA GLY B 103 20.158 1.876 8.507 1.00128.22 C +ATOM 2709 C GLY B 103 20.778 1.681 7.130 1.00109.79 C +ATOM 2710 O GLY B 103 20.369 2.328 6.151 1.00119.25 O +ATOM 2711 N THR B 104 21.765 0.799 7.049 1.00 77.54 N +ATOM 2712 CA THR B 104 22.245 0.359 5.763 1.00 78.56 C +ATOM 2713 C THR B 104 21.620 -0.984 5.430 1.00 82.85 C +ATOM 2714 O THR B 104 21.473 -1.309 4.247 1.00133.02 O +ATOM 2715 CB THR B 104 23.776 0.281 5.701 1.00 73.00 C +ATOM 2716 OG1 THR B 104 24.261 -0.722 6.614 1.00102.58 O +ATOM 2717 CG2 THR B 104 24.371 1.629 6.054 1.00 73.58 C +ATOM 2718 N VAL B 105 21.201 -1.751 6.439 1.00 73.48 N +ATOM 2719 CA VAL B 105 20.810 -3.166 6.194 1.00 97.73 C +ATOM 2720 C VAL B 105 19.595 -3.235 5.278 1.00 90.47 C +ATOM 2721 O VAL B 105 18.710 -2.370 5.348 1.00 94.28 O +ATOM 2722 CB VAL B 105 20.574 -3.985 7.501 1.00110.47 C +ATOM 2723 CG1 VAL B 105 19.440 -4.997 7.328 1.00 92.63 C +ATOM 2724 CG2 VAL B 105 21.866 -4.702 7.954 1.00 98.37 C +ATOM 2725 N ALA B 106 19.627 -4.210 4.365 1.00102.05 N +ATOM 2726 CA ALA B 106 18.673 -4.305 3.266 1.00130.06 C +ATOM 2727 C ALA B 106 17.261 -4.500 3.807 1.00157.08 C +ATOM 2728 O ALA B 106 17.044 -5.311 4.715 1.00208.30 O +ATOM 2729 CB ALA B 106 19.057 -5.458 2.351 1.00120.23 C +ATOM 2730 N ILE B 107 16.313 -3.744 3.256 1.00145.58 N +ATOM 2731 CA ILE B 107 14.946 -3.709 3.767 1.00151.78 C +ATOM 2732 C ILE B 107 14.273 -5.103 3.779 1.00136.02 C +ATOM 2733 O ILE B 107 13.427 -5.397 4.633 1.00131.13 O +ATOM 2734 CB ILE B 107 14.096 -2.696 2.961 1.00141.05 C +ATOM 2735 CG1 ILE B 107 12.761 -2.415 3.662 1.00166.08 C +ATOM 2736 CG2 ILE B 107 13.856 -3.197 1.544 1.00131.77 C +ATOM 2737 CD1 ILE B 107 12.889 -1.892 5.082 1.00160.09 C +ATOM 2738 N ASN B 108 14.659 -5.955 2.837 1.00123.15 N +ATOM 2739 CA ASN B 108 14.179 -7.340 2.788 1.00149.07 C +ATOM 2740 C ASN B 108 14.768 -8.171 3.929 1.00152.93 C +ATOM 2741 O ASN B 108 14.120 -9.073 4.465 1.00157.50 O +ATOM 2742 CB ASN B 108 14.564 -8.005 1.456 1.00157.06 C +ATOM 2743 CG ASN B 108 14.636 -7.022 0.305 1.00153.56 C +ATOM 2744 OD1 ASN B 108 13.631 -6.730 -0.336 1.00174.13 O +ATOM 2745 ND2 ASN B 108 15.827 -6.491 0.051 1.00161.02 N +ATOM 2746 N ASN B 109 16.015 -7.873 4.261 1.00129.94 N +ATOM 2747 CA ASN B 109 16.764 -8.632 5.247 1.00121.07 C +ATOM 2748 C ASN B 109 16.522 -8.166 6.688 1.00108.95 C +ATOM 2749 O ASN B 109 16.823 -8.886 7.643 1.00 83.38 O +ATOM 2750 CB ASN B 109 18.254 -8.543 4.923 1.00133.38 C +ATOM 2751 CG ASN B 109 18.848 -9.887 4.562 1.00160.94 C +ATOM 2752 OD1 ASN B 109 19.682 -10.420 5.295 1.00224.16 O +ATOM 2753 ND2 ASN B 109 18.387 -10.465 3.459 1.00158.65 N +ATOM 2754 N ARG B 110 15.947 -6.972 6.829 1.00108.16 N +ATOM 2755 CA ARG B 110 15.767 -6.309 8.131 1.00 86.12 C +ATOM 2756 C ARG B 110 14.973 -7.192 9.089 1.00 72.27 C +ATOM 2757 O ARG B 110 13.926 -7.739 8.718 1.00 99.73 O +ATOM 2758 CB ARG B 110 15.027 -4.966 7.916 1.00 70.23 C +ATOM 2759 CG ARG B 110 15.242 -3.941 9.007 1.00 71.77 C +ATOM 2760 CD ARG B 110 15.258 -2.522 8.454 1.00 84.17 C +ATOM 2761 NE ARG B 110 13.920 -1.922 8.406 1.00105.61 N +ATOM 2762 CZ ARG B 110 13.528 -0.846 9.111 1.00130.92 C +ATOM 2763 NH1 ARG B 110 14.378 -0.180 9.901 1.00120.67 N +ATOM 2764 NH2 ARG B 110 12.272 -0.417 9.012 1.00133.61 N +ATOM 2765 N ILE B 111 15.430 -7.296 10.327 1.00 56.06 N +ATOM 2766 CA ILE B 111 14.648 -7.985 11.376 1.00 72.54 C +ATOM 2767 C ILE B 111 14.090 -7.000 12.394 1.00 69.29 C +ATOM 2768 O ILE B 111 14.861 -6.346 13.077 1.00 70.10 O +ATOM 2769 CB ILE B 111 15.490 -9.028 12.145 1.00 77.38 C +ATOM 2770 CG1 ILE B 111 15.946 -10.112 11.169 1.00 99.67 C +ATOM 2771 CG2 ILE B 111 14.696 -9.631 13.292 1.00 61.34 C +ATOM 2772 CD1 ILE B 111 17.023 -11.026 11.715 1.00101.41 C +ATOM 2773 N PRO B 112 12.756 -6.900 12.498 1.00 72.34 N +ATOM 2774 CA PRO B 112 12.171 -5.924 13.396 1.00 68.52 C +ATOM 2775 C PRO B 112 12.176 -6.475 14.814 1.00 75.21 C +ATOM 2776 O PRO B 112 11.734 -7.612 15.056 1.00 73.71 O +ATOM 2777 CB PRO B 112 10.756 -5.788 12.862 1.00 85.50 C +ATOM 2778 CG PRO B 112 10.436 -7.148 12.277 1.00 78.48 C +ATOM 2779 CD PRO B 112 11.736 -7.740 11.832 1.00 68.71 C +ATOM 2780 N LEU B 113 12.651 -5.663 15.746 1.00 92.87 N +ATOM 2781 CA LEU B 113 12.832 -6.098 17.118 1.00 99.75 C +ATOM 2782 C LEU B 113 11.802 -5.470 18.052 1.00 95.15 C +ATOM 2783 O LEU B 113 11.534 -4.255 18.035 1.00 64.43 O +ATOM 2784 CB LEU B 113 14.256 -5.792 17.614 1.00114.83 C +ATOM 2785 CG LEU B 113 15.304 -6.849 17.296 1.00126.55 C +ATOM 2786 CD1 LEU B 113 16.610 -6.425 17.935 1.00121.27 C +ATOM 2787 CD2 LEU B 113 14.911 -8.239 17.776 1.00146.91 C +ATOM 2788 N GLN B 114 11.381 -6.302 18.987 1.00 95.54 N +ATOM 2789 CA GLN B 114 10.302 -5.983 19.877 1.00 75.08 C +ATOM 2790 C GLN B 114 10.697 -6.574 21.228 1.00 75.49 C +ATOM 2791 O GLN B 114 11.469 -7.525 21.283 1.00 78.32 O +ATOM 2792 CB GLN B 114 9.061 -6.666 19.355 1.00 68.02 C +ATOM 2793 CG GLN B 114 7.813 -5.930 19.667 1.00 75.42 C +ATOM 2794 CD GLN B 114 6.675 -6.878 19.741 1.00 89.48 C +ATOM 2795 OE1 GLN B 114 6.688 -7.929 19.080 1.00 80.96 O +ATOM 2796 NE2 GLN B 114 5.671 -6.548 20.578 1.00108.76 N +ATOM 2797 N SER B 115 10.249 -5.946 22.307 1.00 72.69 N +ATOM 2798 CA SER B 115 10.664 -6.317 23.673 1.00 55.05 C +ATOM 2799 C SER B 115 10.289 -7.738 23.894 1.00 61.07 C +ATOM 2800 O SER B 115 9.399 -8.283 23.188 1.00103.08 O +ATOM 2801 CB SER B 115 9.955 -5.433 24.706 1.00 64.09 C +ATOM 2802 OG SER B 115 8.526 -5.370 24.478 1.00 76.44 O +ATOM 2803 N LEU B 116 10.937 -8.384 24.846 1.00 76.73 N +ATOM 2804 CA LEU B 116 10.822 -9.849 24.887 1.00104.51 C +ATOM 2805 C LEU B 116 9.489 -10.165 25.494 1.00 92.33 C +ATOM 2806 O LEU B 116 9.147 -9.538 26.490 1.00102.06 O +ATOM 2807 CB LEU B 116 11.928 -10.474 25.727 1.00106.69 C +ATOM 2808 CG LEU B 116 13.359 -10.408 25.168 1.00 86.07 C +ATOM 2809 CD1 LEU B 116 14.121 -9.200 25.724 1.00 60.89 C +ATOM 2810 CD2 LEU B 116 14.060 -11.711 25.481 1.00 72.45 C +ATOM 2811 N THR B 117 8.689 -10.977 24.806 1.00 79.14 N +ATOM 2812 CA THR B 117 7.316 -11.240 25.231 1.00 82.53 C +ATOM 2813 C THR B 117 7.444 -11.799 26.604 1.00 63.42 C +ATOM 2814 O THR B 117 8.274 -12.691 26.813 1.00 38.04 O +ATOM 2815 CB THR B 117 6.604 -12.287 24.330 1.00 95.51 C +ATOM 2816 OG1 THR B 117 6.614 -11.844 22.972 1.00106.89 O +ATOM 2817 CG2 THR B 117 5.161 -12.497 24.763 1.00 87.14 C +ATOM 2818 N ALA B 118 6.604 -11.302 27.519 1.00 52.22 N +ATOM 2819 CA ALA B 118 6.739 -11.630 28.933 1.00 53.00 C +ATOM 2820 C ALA B 118 5.602 -12.436 29.480 1.00 57.11 C +ATOM 2821 O ALA B 118 4.431 -12.171 29.165 1.00 51.38 O +ATOM 2822 CB ALA B 118 6.862 -10.368 29.735 1.00 49.83 C +ATOM 2823 N ALA B 119 5.953 -13.364 30.367 1.00 62.72 N +ATOM 2824 CA ALA B 119 4.995 -14.354 30.863 1.00 91.24 C +ATOM 2825 C ALA B 119 4.262 -13.843 32.095 1.00108.97 C +ATOM 2826 O ALA B 119 4.790 -12.985 32.814 1.00 79.06 O +ATOM 2827 CB ALA B 119 5.712 -15.648 31.192 1.00 88.28 C +ATOM 2828 N ASN B 120 3.049 -14.362 32.341 1.00122.76 N +ATOM 2829 CA ASN B 120 2.317 -14.016 33.572 1.00141.84 C +ATOM 2830 C ASN B 120 2.458 -15.053 34.673 1.00134.19 C +ATOM 2831 O ASN B 120 2.687 -14.726 35.840 1.00111.55 O +ATOM 2832 CB ASN B 120 0.828 -13.807 33.310 1.00123.36 C +ATOM 2833 CG ASN B 120 0.057 -13.434 34.577 1.00132.52 C +ATOM 2834 OD1 ASN B 120 0.563 -12.741 35.480 1.00 83.82 O +ATOM 2835 ND2 ASN B 120 -1.174 -13.931 34.664 1.00168.72 N +ATOM 2836 N ILE B 121 2.275 -16.311 34.307 1.00145.27 N +ATOM 2837 CA ILE B 121 2.547 -17.394 35.233 1.00137.16 C +ATOM 2838 C ILE B 121 3.774 -18.127 34.732 1.00118.72 C +ATOM 2839 O ILE B 121 4.010 -18.252 33.539 1.00121.34 O +ATOM 2840 CB ILE B 121 1.352 -18.366 35.388 1.00113.55 C +ATOM 2841 CG1 ILE B 121 1.185 -19.255 34.157 1.00 92.15 C +ATOM 2842 CG2 ILE B 121 0.078 -17.588 35.682 1.00122.27 C +ATOM 2843 CD1 ILE B 121 1.536 -20.690 34.410 1.00 82.58 C +ATOM 2844 N MET B 122 4.622 -18.515 35.653 1.00104.72 N +ATOM 2845 CA MET B 122 5.661 -19.407 35.283 1.00 90.36 C +ATOM 2846 C MET B 122 5.452 -20.686 36.081 1.00 77.96 C +ATOM 2847 O MET B 122 5.102 -20.651 37.256 1.00103.02 O +ATOM 2848 CB MET B 122 7.041 -18.734 35.445 1.00 78.71 C +ATOM 2849 CG MET B 122 7.365 -18.191 36.821 1.00 96.57 C +ATOM 2850 SD MET B 122 9.164 -18.173 37.067 1.00123.98 S +ATOM 2851 CE MET B 122 9.240 -18.787 38.768 1.00108.37 C +ATOM 2852 N VAL B 123 5.729 -21.817 35.449 1.00 60.98 N +ATOM 2853 CA VAL B 123 5.680 -23.109 36.129 1.00 56.15 C +ATOM 2854 C VAL B 123 7.034 -23.806 36.228 1.00 60.29 C +ATOM 2855 O VAL B 123 7.740 -23.954 35.249 1.00 77.59 O +ATOM 2856 CB VAL B 123 4.739 -24.067 35.411 1.00 47.67 C +ATOM 2857 CG1 VAL B 123 4.915 -23.958 33.916 1.00 48.19 C +ATOM 2858 CG2 VAL B 123 4.922 -25.506 35.897 1.00 44.45 C +ATOM 2859 N GLU B 124 7.411 -24.180 37.440 1.00 67.33 N +ATOM 2860 CA GLU B 124 8.619 -24.942 37.650 1.00 69.92 C +ATOM 2861 C GLU B 124 8.304 -26.174 38.450 1.00 76.82 C +ATOM 2862 O GLU B 124 7.238 -26.307 39.028 1.00106.22 O +ATOM 2863 CB GLU B 124 9.712 -24.111 38.347 1.00 63.01 C +ATOM 2864 CG GLU B 124 9.220 -23.018 39.274 1.00 57.83 C +ATOM 2865 CD GLU B 124 10.285 -21.995 39.546 1.00 64.49 C +ATOM 2866 OE1 GLU B 124 11.103 -21.707 38.633 1.00 71.53 O +ATOM 2867 OE2 GLU B 124 10.374 -21.538 40.704 1.00 71.48 O +ATOM 2868 N GLY B 125 9.283 -27.059 38.521 1.00 97.43 N +ATOM 2869 CA GLY B 125 9.110 -28.319 39.209 1.00 81.29 C +ATOM 2870 C GLY B 125 10.425 -29.098 39.283 1.00 61.48 C +ATOM 2871 O GLY B 125 11.503 -28.528 39.188 1.00 49.89 O +ATOM 2872 N SER B 126 10.321 -30.395 39.534 1.00 44.19 N +ATOM 2873 CA SER B 126 11.484 -31.206 39.853 1.00 46.47 C +ATOM 2874 C SER B 126 11.155 -32.648 39.733 1.00 50.74 C +ATOM 2875 O SER B 126 9.987 -33.039 39.885 1.00 95.98 O +ATOM 2876 CB SER B 126 11.940 -30.992 41.297 1.00 58.21 C +ATOM 2877 OG SER B 126 11.671 -29.669 41.795 1.00 79.09 O +ATOM 2878 N ILE B 127 12.112 -33.426 39.283 1.00 65.32 N +ATOM 2879 CA ILE B 127 11.918 -34.879 39.305 1.00 91.89 C +ATOM 2880 C ILE B 127 12.193 -35.353 40.722 1.00 99.37 C +ATOM 2881 O ILE B 127 13.351 -35.283 41.147 1.00138.60 O +ATOM 2882 CB ILE B 127 12.847 -35.617 38.315 1.00114.14 C +ATOM 2883 CG1 ILE B 127 12.453 -35.315 36.858 1.00118.92 C +ATOM 2884 CG2 ILE B 127 12.806 -37.116 38.576 1.00 85.11 C +ATOM 2885 CD1 ILE B 127 13.618 -35.352 35.883 1.00135.71 C +ATOM 2886 N ILE B 128 11.130 -35.675 41.460 1.00 75.49 N +ATOM 2887 CA ILE B 128 11.204 -35.893 42.918 1.00 79.46 C +ATOM 2888 C ILE B 128 11.322 -37.254 43.484 1.00 81.19 C +ATOM 2889 O ILE B 128 10.927 -37.467 44.665 1.00131.64 O +ATOM 2890 CB ILE B 128 10.018 -35.263 43.664 1.00 80.11 C +ATOM 2891 CG1 ILE B 128 8.701 -35.639 43.000 1.00100.18 C +ATOM 2892 CG2 ILE B 128 10.105 -33.752 43.644 1.00 96.54 C +ATOM 2893 CD1 ILE B 128 7.539 -35.616 43.973 1.00128.54 C +ATOM 2894 N GLY B 129 12.162 -38.036 42.841 1.00 84.51 N +ATOM 2895 CA GLY B 129 12.443 -39.412 43.262 1.00 82.87 C +ATOM 2896 C GLY B 129 12.432 -40.397 42.122 1.00 84.35 C +ATOM 2897 O GLY B 129 11.696 -40.256 41.150 1.00 97.53 O +ATOM 2898 N TYR B 130 13.391 -41.309 42.186 1.00 96.69 N +ATOM 2899 CA TYR B 130 13.363 -42.513 41.385 1.00 88.26 C +ATOM 2900 C TYR B 130 13.837 -43.602 42.324 1.00115.21 C +ATOM 2901 O TYR B 130 15.003 -43.641 42.692 1.00132.06 O +ATOM 2902 CB TYR B 130 14.292 -42.403 40.174 1.00 87.95 C +ATOM 2903 CG TYR B 130 14.395 -43.670 39.348 1.00 76.90 C +ATOM 2904 CD1 TYR B 130 15.100 -44.769 39.818 1.00 70.73 C +ATOM 2905 CD2 TYR B 130 13.854 -43.728 38.053 1.00 84.66 C +ATOM 2906 CE1 TYR B 130 15.276 -45.887 39.027 1.00 87.26 C +ATOM 2907 CE2 TYR B 130 14.040 -44.834 37.250 1.00 92.91 C +ATOM 2908 CZ TYR B 130 14.730 -45.917 37.746 1.00100.57 C +ATOM 2909 OH TYR B 130 14.877 -47.025 36.947 1.00131.12 O +ATOM 2910 N GLU B 131 12.908 -44.422 42.785 1.00131.29 N +ATOM 2911 CA GLU B 131 13.276 -45.617 43.560 1.00145.74 C +ATOM 2912 C GLU B 131 13.293 -46.809 42.594 1.00123.90 C +ATOM 2913 O GLU B 131 12.573 -46.813 41.583 1.00130.40 O +ATOM 2914 CB GLU B 131 12.371 -45.870 44.799 1.00186.31 C +ATOM 2915 CG GLU B 131 12.873 -45.117 46.097 1.00196.20 C +ATOM 2916 CD GLU B 131 13.469 -43.719 45.799 1.00203.06 C +ATOM 2917 OE1 GLU B 131 12.810 -42.808 45.258 1.00167.19 O +ATOM 2918 OE2 GLU B 131 14.607 -43.466 46.196 1.00170.29 O +ATOM 2919 N SER B 132 14.194 -47.755 42.837 1.00106.61 N +ATOM 2920 CA SER B 132 14.454 -48.811 41.865 1.00 98.04 C +ATOM 2921 C SER B 132 14.140 -50.167 42.464 1.00104.17 C +ATOM 2922 O SER B 132 14.437 -50.426 43.633 1.00120.50 O +ATOM 2923 CB SER B 132 15.906 -48.759 41.374 1.00 93.20 C +ATOM 2924 OG SER B 132 16.648 -49.873 41.830 1.00 82.26 O +ATOM 2925 N ASN B 133 13.576 -51.045 41.643 1.00115.64 N +ATOM 2926 CA ASN B 133 13.035 -52.328 42.116 1.00130.57 C +ATOM 2927 C ASN B 133 12.143 -52.148 43.335 1.00120.84 C +ATOM 2928 O ASN B 133 12.383 -52.734 44.389 1.00120.36 O +ATOM 2929 CB ASN B 133 14.148 -53.330 42.432 1.00120.62 C +ATOM 2930 CG ASN B 133 15.013 -53.628 41.232 1.00126.41 C +ATOM 2931 OD1 ASN B 133 14.561 -53.576 40.073 1.00132.27 O +ATOM 2932 ND2 ASN B 133 16.272 -53.923 41.487 1.00155.15 N +ATOM 2933 N VAL B 134 11.142 -51.294 43.173 1.00115.10 N +ATOM 2934 CA VAL B 134 10.195 -51.003 44.227 1.00114.84 C +ATOM 2935 C VAL B 134 9.403 -52.284 44.452 1.00114.29 C +ATOM 2936 O VAL B 134 9.031 -52.609 45.585 1.00115.40 O +ATOM 2937 CB VAL B 134 9.270 -49.817 43.836 1.00124.06 C +ATOM 2938 CG1 VAL B 134 8.320 -49.469 44.968 1.00125.33 C +ATOM 2939 CG2 VAL B 134 10.099 -48.594 43.468 1.00116.62 C +ATOM 2940 N LYS B 135 9.148 -53.012 43.363 1.00110.38 N +ATOM 2941 CA LYS B 135 8.702 -54.401 43.465 1.00104.37 C +ATOM 2942 C LYS B 135 9.439 -55.296 42.493 1.00101.11 C +ATOM 2943 O LYS B 135 9.966 -54.834 41.467 1.00140.52 O +ATOM 2944 CB LYS B 135 7.198 -54.505 43.201 1.00121.03 C +ATOM 2945 CG LYS B 135 6.348 -53.753 44.216 1.00143.47 C +ATOM 2946 CD LYS B 135 4.880 -53.803 43.833 1.00142.76 C +ATOM 2947 CE LYS B 135 4.018 -53.045 44.821 1.00131.46 C +ATOM 2948 NZ LYS B 135 2.610 -53.504 44.731 1.00131.03 N +ATOM 2949 N SER B 136 9.441 -56.590 42.794 1.00111.05 N +ATOM 2950 CA SER B 136 10.081 -57.580 41.925 1.00131.16 C +ATOM 2951 C SER B 136 9.639 -59.006 42.238 1.00118.20 C +ATOM 2952 O SER B 136 9.123 -59.275 43.319 1.00 99.56 O +ATOM 2953 CB SER B 136 11.597 -57.495 42.043 1.00144.75 C +ATOM 2954 OG SER B 136 12.153 -58.758 42.379 1.00127.71 O +ATOM 2955 N GLY B 137 9.755 -59.888 41.245 1.00125.60 N +ATOM 2956 CA GLY B 137 9.324 -61.276 41.406 1.00131.98 C +ATOM 2957 C GLY B 137 9.765 -62.188 40.280 1.00125.14 C +ATOM 2958 O GLY B 137 10.370 -61.735 39.305 1.00 80.59 O +ATOM 2959 N GLY B 138 9.488 -63.480 40.435 1.00125.41 N +ATOM 2960 CA GLY B 138 9.908 -64.466 39.450 1.00131.48 C +ATOM 2961 C GLY B 138 9.288 -65.828 39.660 1.00101.90 C +ATOM 2962 O GLY B 138 9.042 -66.243 40.787 1.00 94.64 O +ATOM 2963 N VAL B 139 9.007 -66.505 38.556 1.00100.16 N +ATOM 2964 CA VAL B 139 8.420 -67.838 38.587 1.00101.63 C +ATOM 2965 C VAL B 139 9.051 -68.693 37.501 1.00115.59 C +ATOM 2966 O VAL B 139 9.042 -68.331 36.317 1.00111.57 O +ATOM 2967 CB VAL B 139 6.887 -67.820 38.356 1.00 91.16 C +ATOM 2968 CG1 VAL B 139 6.356 -69.236 38.268 1.00 82.29 C +ATOM 2969 CG2 VAL B 139 6.172 -67.057 39.466 1.00 93.94 C +ATOM 2970 N GLY B 140 9.563 -69.850 37.903 1.00130.58 N +ATOM 2971 CA GLY B 140 10.213 -70.763 36.971 1.00137.10 C +ATOM 2972 C GLY B 140 10.088 -72.219 37.363 1.00125.39 C +ATOM 2973 O GLY B 140 10.097 -72.558 38.552 1.00145.86 O +ATOM 2974 N ALA B 141 10.022 -73.090 36.362 1.00110.48 N +ATOM 2975 CA ALA B 141 10.057 -74.523 36.609 1.00104.10 C +ATOM 2976 C ALA B 141 10.847 -75.269 35.543 1.00114.55 C +ATOM 2977 O ALA B 141 10.798 -74.947 34.357 1.00113.97 O +ATOM 2978 CB ALA B 141 8.650 -75.078 36.716 1.00103.73 C +ATOM 2979 N ARG B 142 11.614 -76.251 35.989 1.00164.00 N +ATOM 2980 CA ARG B 142 12.274 -77.155 35.078 1.00192.46 C +ATOM 2981 C ARG B 142 11.964 -78.578 35.509 1.00192.24 C +ATOM 2982 O ARG B 142 11.871 -78.865 36.705 1.00206.20 O +ATOM 2983 CB ARG B 142 13.792 -76.906 35.028 1.00202.64 C +ATOM 2984 CG ARG B 142 14.502 -77.785 34.003 1.00201.67 C +ATOM 2985 CD ARG B 142 15.557 -77.031 33.227 1.00180.69 C +ATOM 2986 NE ARG B 142 16.753 -76.898 34.046 1.00183.80 N +ATOM 2987 CZ ARG B 142 17.635 -75.912 33.931 1.00195.19 C +ATOM 2988 NH1 ARG B 142 17.519 -74.997 32.972 1.00187.85 N +ATOM 2989 NH2 ARG B 142 18.685 -75.870 34.745 1.00211.18 N +ATOM 2990 N TYR B 143 11.817 -79.456 34.523 1.00183.53 N +ATOM 2991 CA TYR B 143 11.461 -80.840 34.744 1.00177.37 C +ATOM 2992 C TYR B 143 12.416 -81.761 33.959 1.00154.46 C +ATOM 2993 O TYR B 143 12.074 -82.299 32.907 1.00101.97 O +ATOM 2994 CB TYR B 143 9.993 -81.080 34.336 1.00189.27 C +ATOM 2995 CG TYR B 143 9.541 -82.472 34.681 1.00204.03 C +ATOM 2996 CD1 TYR B 143 9.429 -82.870 36.012 1.00201.94 C +ATOM 2997 CD2 TYR B 143 9.396 -83.431 33.697 1.00198.47 C +ATOM 2998 CE1 TYR B 143 9.158 -84.178 36.362 1.00178.00 C +ATOM 2999 CE2 TYR B 143 9.110 -84.743 34.035 1.00202.56 C +ATOM 3000 CZ TYR B 143 8.997 -85.110 35.367 1.00177.48 C +ATOM 3001 OH TYR B 143 8.724 -86.409 35.700 1.00143.57 O +ATOM 3002 N GLY B 145 15.182 -82.576 29.495 1.00112.67 N +ATOM 3003 CA GLY B 145 14.781 -81.770 30.646 1.00134.90 C +ATOM 3004 C GLY B 145 14.350 -80.377 30.206 1.00172.93 C +ATOM 3005 O GLY B 145 15.107 -79.613 29.600 1.00177.44 O +ATOM 3006 N ILE B 146 13.104 -80.039 30.533 1.00213.51 N +ATOM 3007 CA ILE B 146 12.405 -78.911 29.893 1.00188.90 C +ATOM 3008 C ILE B 146 12.067 -77.851 30.939 1.00158.99 C +ATOM 3009 O ILE B 146 11.633 -78.189 32.041 1.00129.28 O +ATOM 3010 CB ILE B 146 11.100 -79.367 29.185 1.00168.03 C +ATOM 3011 CG1 ILE B 146 11.298 -80.733 28.507 1.00174.66 C +ATOM 3012 CG2 ILE B 146 10.653 -78.327 28.165 1.00129.33 C +ATOM 3013 CD1 ILE B 146 10.837 -81.924 29.330 1.00154.15 C +ATOM 3014 N GLY B 147 12.281 -76.578 30.610 1.00141.52 N +ATOM 3015 CA GLY B 147 12.081 -75.513 31.591 1.00145.28 C +ATOM 3016 C GLY B 147 11.728 -74.138 31.049 1.00133.47 C +ATOM 3017 O GLY B 147 11.988 -73.815 29.891 1.00 98.26 O +ATOM 3018 N ALA B 148 11.097 -73.338 31.901 1.00128.95 N +ATOM 3019 CA ALA B 148 10.822 -71.952 31.584 1.00118.03 C +ATOM 3020 C ALA B 148 10.816 -71.119 32.859 1.00113.70 C +ATOM 3021 O ALA B 148 10.772 -71.649 33.972 1.00 79.81 O +ATOM 3022 CB ALA B 148 9.489 -71.808 30.846 1.00116.47 C +ATOM 3023 N ASP B 149 10.857 -69.804 32.686 1.00138.81 N +ATOM 3024 CA ASP B 149 10.804 -68.885 33.818 1.00145.33 C +ATOM 3025 C ASP B 149 10.567 -67.454 33.357 1.00152.11 C +ATOM 3026 O ASP B 149 10.980 -67.071 32.254 1.00176.93 O +ATOM 3027 CB ASP B 149 12.099 -68.963 34.638 1.00163.37 C +ATOM 3028 CG ASP B 149 13.221 -68.171 34.023 1.00177.91 C +ATOM 3029 OD1 ASP B 149 13.796 -68.656 33.028 1.00219.24 O +ATOM 3030 OD2 ASP B 149 13.551 -67.103 34.563 1.00153.69 O +ATOM 3031 N THR B 150 9.875 -66.679 34.182 1.00147.04 N +ATOM 3032 CA THR B 150 9.848 -65.231 34.004 1.00141.07 C +ATOM 3033 C THR B 150 10.337 -64.551 35.269 1.00128.60 C +ATOM 3034 O THR B 150 10.265 -65.109 36.360 1.00128.50 O +ATOM 3035 CB THR B 150 8.446 -64.696 33.655 1.00144.75 C +ATOM 3036 OG1 THR B 150 7.520 -65.043 34.690 1.00164.79 O +ATOM 3037 CG2 THR B 150 7.960 -65.263 32.330 1.00155.37 C +ATOM 3038 N GLN B 151 10.880 -63.357 35.105 1.00135.76 N +ATOM 3039 CA GLN B 151 11.217 -62.506 36.256 1.00126.64 C +ATOM 3040 C GLN B 151 10.838 -61.063 35.910 1.00115.58 C +ATOM 3041 O GLN B 151 10.834 -60.667 34.736 1.00106.25 O +ATOM 3042 CB GLN B 151 12.688 -62.663 36.733 1.00138.51 C +ATOM 3043 CG GLN B 151 13.734 -62.095 35.795 1.00165.97 C +ATOM 3044 CD GLN B 151 15.074 -61.841 36.477 1.00168.36 C +ATOM 3045 OE1 GLN B 151 15.510 -62.630 37.302 1.00159.71 O +ATOM 3046 NE2 GLN B 151 15.729 -60.729 36.132 1.00175.37 N +ATOM 3047 N TYR B 152 10.387 -60.318 36.906 1.00 92.16 N +ATOM 3048 CA TYR B 152 9.965 -58.948 36.667 1.00 94.47 C +ATOM 3049 C TYR B 152 10.429 -58.029 37.762 1.00103.55 C +ATOM 3050 O TYR B 152 10.552 -58.432 38.918 1.00 96.14 O +ATOM 3051 CB TYR B 152 8.446 -58.843 36.514 1.00 94.57 C +ATOM 3052 CG TYR B 152 7.679 -58.261 37.693 1.00 81.90 C +ATOM 3053 CD1 TYR B 152 7.634 -58.914 38.916 1.00 79.03 C +ATOM 3054 CD2 TYR B 152 6.880 -57.150 37.528 1.00 87.29 C +ATOM 3055 CE1 TYR B 152 6.860 -58.438 39.965 1.00 90.20 C +ATOM 3056 CE2 TYR B 152 6.093 -56.669 38.563 1.00105.72 C +ATOM 3057 CZ TYR B 152 6.091 -57.306 39.784 1.00107.43 C +ATOM 3058 OH TYR B 152 5.310 -56.823 40.818 1.00123.67 O +ATOM 3059 N GLN B 153 10.712 -56.791 37.383 1.00109.15 N +ATOM 3060 CA GLN B 153 10.997 -55.759 38.355 1.00104.99 C +ATOM 3061 C GLN B 153 10.270 -54.495 37.957 1.00 95.36 C +ATOM 3062 O GLN B 153 9.997 -54.262 36.773 1.00123.59 O +ATOM 3063 CB GLN B 153 12.514 -55.524 38.439 1.00153.75 C +ATOM 3064 CG GLN B 153 13.330 -56.714 38.982 1.00193.69 C +ATOM 3065 CD GLN B 153 14.851 -56.482 38.879 1.00222.34 C +ATOM 3066 OE1 GLN B 153 15.316 -55.616 38.122 1.00235.72 O +ATOM 3067 NE2 GLN B 153 15.619 -57.186 39.707 1.00226.95 N +ATOM 3068 N LEU B 154 9.992 -53.645 38.930 1.00 91.20 N +ATOM 3069 CA LEU B 154 9.445 -52.327 38.617 1.00109.93 C +ATOM 3070 C LEU B 154 9.930 -51.218 39.544 1.00107.02 C +ATOM 3071 O LEU B 154 10.120 -51.429 40.757 1.00 85.48 O +ATOM 3072 CB LEU B 154 7.914 -52.362 38.604 1.00100.44 C +ATOM 3073 CG LEU B 154 7.243 -52.500 39.972 1.00106.35 C +ATOM 3074 CD1 LEU B 154 6.853 -51.150 40.542 1.00 92.60 C +ATOM 3075 CD2 LEU B 154 6.036 -53.414 39.842 1.00135.23 C +ATOM 3076 N ASP B 155 10.036 -50.026 38.951 1.00108.62 N +ATOM 3077 CA ASP B 155 10.677 -48.869 39.557 1.00110.30 C +ATOM 3078 C ASP B 155 9.655 -47.745 39.622 1.00103.21 C +ATOM 3079 O ASP B 155 8.677 -47.746 38.887 1.00 83.02 O +ATOM 3080 CB ASP B 155 11.891 -48.440 38.713 1.00114.11 C +ATOM 3081 CG ASP B 155 12.782 -49.615 38.335 1.00139.76 C +ATOM 3082 OD1 ASP B 155 12.444 -50.346 37.384 1.00153.88 O +ATOM 3083 OD2 ASP B 155 13.828 -49.815 38.982 1.00137.26 O +ATOM 3084 N GLN B 156 9.906 -46.753 40.468 1.00103.19 N +ATOM 3085 CA GLN B 156 9.019 -45.590 40.553 1.00 86.84 C +ATOM 3086 C GLN B 156 9.694 -44.305 40.042 1.00 83.76 C +ATOM 3087 O GLN B 156 10.921 -44.165 40.117 1.00109.75 O +ATOM 3088 CB GLN B 156 8.532 -45.445 41.993 1.00 82.36 C +ATOM 3089 CG GLN B 156 7.380 -44.478 42.168 1.00 84.70 C +ATOM 3090 CD GLN B 156 6.611 -44.710 43.459 1.00 89.58 C +ATOM 3091 OE1 GLN B 156 7.034 -45.487 44.331 1.00 95.18 O +ATOM 3092 NE2 GLN B 156 5.468 -44.041 43.586 1.00 71.65 N +ATOM 3093 N ILE B 157 8.888 -43.349 39.594 1.00 69.63 N +ATOM 3094 CA ILE B 157 9.386 -41.998 39.270 1.00 67.46 C +ATOM 3095 C ILE B 157 8.288 -40.939 39.517 1.00 50.92 C +ATOM 3096 O ILE B 157 7.104 -41.238 39.409 1.00 40.93 O +ATOM 3097 CB ILE B 157 9.801 -41.952 37.811 1.00 60.79 C +ATOM 3098 CG1 ILE B 157 10.810 -40.861 37.576 1.00 61.21 C +ATOM 3099 CG2 ILE B 157 8.582 -41.740 36.940 1.00 62.03 C +ATOM 3100 CD1 ILE B 157 11.409 -40.872 36.181 1.00 60.42 C +ATOM 3101 N ALA B 158 8.665 -39.822 40.114 1.00 47.04 N +ATOM 3102 CA ALA B 158 7.670 -38.873 40.535 1.00 66.02 C +ATOM 3103 C ALA B 158 8.101 -37.508 40.099 1.00 90.24 C +ATOM 3104 O ALA B 158 9.300 -37.216 40.018 1.00 73.03 O +ATOM 3105 CB ALA B 158 7.406 -38.907 42.049 1.00 64.82 C +ATOM 3106 N VAL B 159 7.109 -36.662 39.839 1.00100.64 N +ATOM 3107 CA VAL B 159 7.368 -35.345 39.315 1.00116.86 C +ATOM 3108 C VAL B 159 6.488 -34.307 39.999 1.00100.20 C +ATOM 3109 O VAL B 159 5.280 -34.467 40.105 1.00129.61 O +ATOM 3110 CB VAL B 159 7.149 -35.324 37.795 1.00138.38 C +ATOM 3111 CG1 VAL B 159 6.939 -33.908 37.292 1.00148.92 C +ATOM 3112 CG2 VAL B 159 8.332 -35.958 37.076 1.00146.63 C +ATOM 3113 N ASN B 160 7.124 -33.247 40.482 1.00 79.89 N +ATOM 3114 CA ASN B 160 6.431 -32.063 40.958 1.00 81.71 C +ATOM 3115 C ASN B 160 6.392 -31.031 39.816 1.00 93.38 C +ATOM 3116 O ASN B 160 7.402 -30.765 39.169 1.00 93.77 O +ATOM 3117 CB ASN B 160 7.182 -31.500 42.172 1.00 73.35 C +ATOM 3118 CG ASN B 160 6.618 -30.181 42.700 1.00 88.16 C +ATOM 3119 OD1 ASN B 160 6.275 -29.254 41.939 1.00 79.30 O +ATOM 3120 ND2 ASN B 160 6.527 -30.091 44.023 1.00 79.65 N +ATOM 3121 N LEU B 161 5.206 -30.506 39.541 1.00 99.68 N +ATOM 3122 CA LEU B 161 5.066 -29.281 38.761 1.00 88.74 C +ATOM 3123 C LEU B 161 4.260 -28.275 39.564 1.00 93.20 C +ATOM 3124 O LEU B 161 3.380 -28.639 40.345 1.00138.50 O +ATOM 3125 CB LEU B 161 4.346 -29.553 37.449 1.00 79.15 C +ATOM 3126 CG LEU B 161 5.077 -30.455 36.485 1.00 98.77 C +ATOM 3127 CD1 LEU B 161 4.169 -30.790 35.310 1.00 97.28 C +ATOM 3128 CD2 LEU B 161 6.363 -29.779 36.023 1.00119.70 C +ATOM 3129 N ARG B 162 4.550 -27.004 39.394 1.00 79.13 N +ATOM 3130 CA ARG B 162 3.845 -25.998 40.179 1.00 59.23 C +ATOM 3131 C ARG B 162 3.813 -24.642 39.540 1.00 53.22 C +ATOM 3132 O ARG B 162 4.820 -24.128 39.027 1.00 83.81 O +ATOM 3133 CB ARG B 162 4.413 -25.902 41.602 1.00 68.78 C +ATOM 3134 CG ARG B 162 5.866 -25.450 41.760 1.00 79.90 C +ATOM 3135 CD ARG B 162 6.125 -25.003 43.200 1.00 74.85 C +ATOM 3136 NE ARG B 162 7.409 -24.360 43.431 1.00 73.05 N +ATOM 3137 CZ ARG B 162 8.545 -25.021 43.598 1.00 93.11 C +ATOM 3138 NH1 ARG B 162 8.596 -26.352 43.475 1.00103.36 N +ATOM 3139 NH2 ARG B 162 9.658 -24.347 43.843 1.00109.16 N +ATOM 3140 N VAL B 163 2.619 -24.097 39.482 1.00 62.17 N +ATOM 3141 CA VAL B 163 2.378 -22.778 38.892 1.00 77.59 C +ATOM 3142 C VAL B 163 2.673 -21.715 39.928 1.00 53.24 C +ATOM 3143 O VAL B 163 1.979 -21.667 40.951 1.00 91.99 O +ATOM 3144 CB VAL B 163 0.891 -22.606 38.445 1.00 92.43 C +ATOM 3145 CG1 VAL B 163 0.674 -21.195 37.871 1.00 98.56 C +ATOM 3146 CG2 VAL B 163 0.488 -23.706 37.457 1.00 78.83 C +ATOM 3147 N VAL B 164 3.523 -20.776 39.560 1.00 35.12 N +ATOM 3148 CA VAL B 164 3.844 -19.644 40.402 1.00 37.86 C +ATOM 3149 C VAL B 164 3.375 -18.396 39.747 1.00 38.80 C +ATOM 3150 O VAL B 164 3.581 -18.198 38.548 1.00 44.33 O +ATOM 3151 CB VAL B 164 5.356 -19.504 40.594 1.00 50.51 C +ATOM 3152 CG1 VAL B 164 5.697 -18.304 41.455 1.00 35.75 C +ATOM 3153 CG2 VAL B 164 5.890 -20.786 41.231 1.00 80.41 C +ATOM 3154 N ASN B 165 2.738 -17.548 40.534 1.00 49.23 N +ATOM 3155 CA ASN B 165 2.256 -16.280 40.034 1.00 64.08 C +ATOM 3156 C ASN B 165 3.393 -15.232 40.073 1.00 90.99 C +ATOM 3157 O ASN B 165 3.906 -14.882 41.148 1.00 69.47 O +ATOM 3158 CB ASN B 165 1.080 -15.771 40.845 1.00 62.73 C +ATOM 3159 CG ASN B 165 0.403 -14.587 40.188 1.00 83.87 C +ATOM 3160 OD1 ASN B 165 0.757 -14.192 39.073 1.00 90.93 O +ATOM 3161 ND2 ASN B 165 -0.414 -13.891 40.954 1.00105.54 N +ATOM 3162 N VAL B 166 3.753 -14.715 38.890 1.00 86.93 N +ATOM 3163 CA VAL B 166 4.848 -13.752 38.742 1.00 65.72 C +ATOM 3164 C VAL B 166 4.580 -12.529 39.574 1.00 62.63 C +ATOM 3165 O VAL B 166 5.467 -11.980 40.174 1.00 54.30 O +ATOM 3166 CB VAL B 166 5.047 -13.361 37.251 1.00 62.07 C +ATOM 3167 CG1 VAL B 166 5.704 -11.985 37.098 1.00 49.30 C +ATOM 3168 CG2 VAL B 166 5.840 -14.476 36.541 1.00 74.82 C +ATOM 3169 N SER B 167 3.324 -12.111 39.585 1.00 73.17 N +ATOM 3170 CA SER B 167 2.957 -10.837 40.156 1.00 73.17 C +ATOM 3171 C SER B 167 3.075 -10.843 41.673 1.00 75.85 C +ATOM 3172 O SER B 167 2.970 -9.774 42.288 1.00 70.00 O +ATOM 3173 CB SER B 167 1.543 -10.461 39.685 1.00 80.45 C +ATOM 3174 OG SER B 167 1.397 -10.666 38.283 1.00113.27 O +ATOM 3175 N THR B 168 3.184 -12.033 42.282 1.00 73.94 N +ATOM 3176 CA THR B 168 3.122 -12.131 43.750 1.00 73.71 C +ATOM 3177 C THR B 168 4.091 -13.103 44.320 1.00 53.09 C +ATOM 3178 O THR B 168 4.653 -12.908 45.427 1.00 67.61 O +ATOM 3179 CB THR B 168 1.731 -12.561 44.273 1.00 84.35 C +ATOM 3180 OG1 THR B 168 1.298 -13.733 43.584 1.00 71.18 O +ATOM 3181 CG2 THR B 168 0.700 -11.441 44.084 1.00105.64 C +ATOM 3182 N GLY B 169 4.304 -14.177 43.598 1.00 45.18 N +ATOM 3183 CA GLY B 169 5.163 -15.213 44.150 1.00 75.79 C +ATOM 3184 C GLY B 169 4.370 -16.281 44.871 1.00 65.21 C +ATOM 3185 O GLY B 169 4.910 -17.334 45.180 1.00 58.90 O +ATOM 3186 N GLU B 170 3.098 -16.007 45.124 1.00 65.87 N +ATOM 3187 CA GLU B 170 2.165 -17.059 45.516 1.00 64.25 C +ATOM 3188 C GLU B 170 2.268 -18.203 44.535 1.00 56.25 C +ATOM 3189 O GLU B 170 2.205 -18.024 43.301 1.00 67.57 O +ATOM 3190 CB GLU B 170 0.708 -16.553 45.508 1.00 92.95 C +ATOM 3191 CG GLU B 170 0.354 -15.673 46.699 1.00118.31 C +ATOM 3192 CD GLU B 170 -0.621 -14.541 46.385 1.00135.11 C +ATOM 3193 OE1 GLU B 170 -0.863 -14.263 45.191 1.00142.16 O +ATOM 3194 OE2 GLU B 170 -1.061 -13.849 47.331 1.00136.85 O +ATOM 3195 N ILE B 171 2.452 -19.392 45.055 1.00 46.56 N +ATOM 3196 CA ILE B 171 2.283 -20.574 44.222 1.00 56.00 C +ATOM 3197 C ILE B 171 0.791 -20.797 44.019 1.00 68.06 C +ATOM 3198 O ILE B 171 0.026 -20.775 44.976 1.00 98.08 O +ATOM 3199 CB ILE B 171 2.889 -21.808 44.899 1.00 66.28 C +ATOM 3200 CG1 ILE B 171 4.423 -21.709 44.870 1.00 93.82 C +ATOM 3201 CG2 ILE B 171 2.395 -23.074 44.212 1.00 59.12 C +ATOM 3202 CD1 ILE B 171 5.114 -22.642 45.835 1.00 84.41 C +ATOM 3203 N LEU B 172 0.360 -20.908 42.771 1.00 77.63 N +ATOM 3204 CA LEU B 172 -1.070 -20.955 42.473 1.00 64.37 C +ATOM 3205 C LEU B 172 -1.533 -22.388 42.369 1.00 66.62 C +ATOM 3206 O LEU B 172 -2.751 -22.670 42.348 1.00120.21 O +ATOM 3207 CB LEU B 172 -1.420 -20.181 41.182 1.00 54.39 C +ATOM 3208 CG LEU B 172 -1.323 -18.635 41.307 1.00 62.14 C +ATOM 3209 CD1 LEU B 172 -1.780 -17.798 40.111 1.00 61.85 C +ATOM 3210 CD2 LEU B 172 -1.927 -18.103 42.608 1.00 70.17 C +ATOM 3211 N SER B 173 -0.576 -23.297 42.296 1.00 58.03 N +ATOM 3212 CA SER B 173 -0.887 -24.695 42.202 1.00 78.77 C +ATOM 3213 C SER B 173 0.373 -25.528 42.347 1.00 87.17 C +ATOM 3214 O SER B 173 1.338 -25.335 41.627 1.00100.21 O +ATOM 3215 CB SER B 173 -1.563 -25.007 40.852 1.00 98.72 C +ATOM 3216 OG SER B 173 -1.578 -26.411 40.598 1.00161.85 O +ATOM 3217 N SER B 174 0.305 -26.565 43.174 1.00114.41 N +ATOM 3218 CA SER B 174 1.330 -27.620 43.184 1.00108.31 C +ATOM 3219 C SER B 174 0.689 -28.974 42.932 1.00 73.08 C +ATOM 3220 O SER B 174 -0.367 -29.276 43.476 1.00 62.04 O +ATOM 3221 CB SER B 174 2.071 -27.646 44.535 1.00119.97 C +ATOM 3222 OG SER B 174 3.232 -28.460 44.497 1.00112.62 O +ATOM 3223 N VAL B 175 1.341 -29.785 42.113 1.00 68.61 N +ATOM 3224 CA VAL B 175 0.852 -31.127 41.812 1.00 91.69 C +ATOM 3225 C VAL B 175 1.975 -32.141 41.842 1.00 86.21 C +ATOM 3226 O VAL B 175 3.099 -31.847 41.387 1.00127.27 O +ATOM 3227 CB VAL B 175 0.134 -31.185 40.437 1.00109.82 C +ATOM 3228 CG1 VAL B 175 -1.097 -30.301 40.446 1.00132.93 C +ATOM 3229 CG2 VAL B 175 1.042 -30.740 39.303 1.00124.44 C +ATOM 3230 N ASN B 176 1.639 -33.355 42.251 1.00 78.80 N +ATOM 3231 CA ASN B 176 2.633 -34.394 42.442 1.00 99.42 C +ATOM 3232 C ASN B 176 2.260 -35.678 41.719 1.00103.20 C +ATOM 3233 O ASN B 176 1.586 -36.520 42.298 1.00141.84 O +ATOM 3234 CB ASN B 176 2.787 -34.643 43.946 1.00 96.69 C +ATOM 3235 CG ASN B 176 3.943 -33.852 44.549 1.00112.92 C +ATOM 3236 OD1 ASN B 176 4.477 -32.976 43.883 1.00109.93 O +ATOM 3237 ND2 ASN B 176 4.391 -34.190 45.785 1.00148.55 N +ATOM 3238 N THR B 177 2.780 -35.880 40.508 1.00100.08 N +ATOM 3239 CA THR B 177 2.460 -37.080 39.732 1.00 99.71 C +ATOM 3240 C THR B 177 3.530 -38.169 39.865 1.00 91.54 C +ATOM 3241 O THR B 177 4.651 -37.907 40.277 1.00 71.48 O +ATOM 3242 CB THR B 177 2.270 -36.767 38.243 1.00 97.26 C +ATOM 3243 OG1 THR B 177 3.540 -36.441 37.665 1.00131.68 O +ATOM 3244 CG2 THR B 177 1.306 -35.606 38.051 1.00 84.42 C +ATOM 3245 N SER B 178 3.139 -39.402 39.559 1.00 91.00 N +ATOM 3246 CA SER B 178 4.006 -40.554 39.741 1.00 96.52 C +ATOM 3247 C SER B 178 3.754 -41.577 38.648 1.00 92.04 C +ATOM 3248 O SER B 178 2.634 -41.720 38.145 1.00100.69 O +ATOM 3249 CB SER B 178 3.802 -41.192 41.128 1.00112.38 C +ATOM 3250 OG SER B 178 4.400 -42.489 41.210 1.00167.73 O +ATOM 3251 N LYS B 179 4.771 -42.380 38.360 1.00 92.93 N +ATOM 3252 CA LYS B 179 4.652 -43.369 37.306 1.00101.00 C +ATOM 3253 C LYS B 179 5.606 -44.544 37.542 1.00121.80 C +ATOM 3254 O LYS B 179 6.704 -44.387 38.086 1.00141.72 O +ATOM 3255 CB LYS B 179 4.944 -42.679 35.989 1.00103.40 C +ATOM 3256 CG LYS B 179 4.117 -43.167 34.822 1.00118.77 C +ATOM 3257 CD LYS B 179 4.872 -44.232 34.061 1.00129.62 C +ATOM 3258 CE LYS B 179 3.994 -44.850 32.994 1.00125.56 C +ATOM 3259 NZ LYS B 179 4.596 -46.092 32.447 1.00112.44 N +ATOM 3260 N THR B 180 5.160 -45.733 37.151 1.00116.82 N +ATOM 3261 CA THR B 180 5.920 -46.953 37.396 1.00109.20 C +ATOM 3262 C THR B 180 6.570 -47.478 36.105 1.00114.65 C +ATOM 3263 O THR B 180 5.921 -47.544 35.035 1.00134.53 O +ATOM 3264 CB THR B 180 5.053 -48.044 38.040 1.00112.39 C +ATOM 3265 OG1 THR B 180 5.606 -49.333 37.750 1.00127.34 O +ATOM 3266 CG2 THR B 180 3.611 -47.976 37.525 1.00132.48 C +ATOM 3267 N ILE B 181 7.857 -47.813 36.202 1.00 91.94 N +ATOM 3268 CA ILE B 181 8.603 -48.340 35.060 1.00 93.81 C +ATOM 3269 C ILE B 181 8.735 -49.866 35.133 1.00110.53 C +ATOM 3270 O ILE B 181 9.294 -50.411 36.087 1.00 89.88 O +ATOM 3271 CB ILE B 181 10.006 -47.723 34.976 1.00 90.33 C +ATOM 3272 CG1 ILE B 181 9.921 -46.196 34.996 1.00 79.25 C +ATOM 3273 CG2 ILE B 181 10.731 -48.159 33.706 1.00 99.60 C +ATOM 3274 CD1 ILE B 181 10.648 -45.573 36.171 1.00 90.36 C +ATOM 3275 N LEU B 182 8.153 -50.550 34.143 1.00131.35 N +ATOM 3276 CA LEU B 182 8.089 -52.021 34.125 1.00141.25 C +ATOM 3277 C LEU B 182 9.241 -52.673 33.363 1.00125.85 C +ATOM 3278 O LEU B 182 9.618 -52.225 32.280 1.00106.81 O +ATOM 3279 CB LEU B 182 6.768 -52.488 33.507 1.00139.06 C +ATOM 3280 CG LEU B 182 6.584 -54.009 33.398 1.00126.37 C +ATOM 3281 CD1 LEU B 182 6.577 -54.710 34.752 1.00120.82 C +ATOM 3282 CD2 LEU B 182 5.302 -54.276 32.635 1.00119.31 C +ATOM 3283 N SER B 183 9.738 -53.773 33.919 1.00129.89 N +ATOM 3284 CA SER B 183 10.761 -54.579 33.275 1.00117.92 C +ATOM 3285 C SER B 183 10.456 -56.068 33.494 1.00 85.05 C +ATOM 3286 O SER B 183 10.058 -56.466 34.588 1.00 51.10 O +ATOM 3287 CB SER B 183 12.148 -54.219 33.846 1.00143.43 C +ATOM 3288 OG SER B 183 12.254 -52.825 34.103 1.00113.16 O +ATOM 3289 N TYR B 184 10.705 -56.880 32.475 1.00 75.21 N +ATOM 3290 CA TYR B 184 10.527 -58.321 32.602 1.00 76.39 C +ATOM 3291 C TYR B 184 11.381 -59.150 31.645 1.00 82.92 C +ATOM 3292 O TYR B 184 11.841 -58.696 30.583 1.00 65.72 O +ATOM 3293 CB TYR B 184 9.051 -58.710 32.434 1.00 92.01 C +ATOM 3294 CG TYR B 184 8.422 -58.306 31.115 1.00 88.52 C +ATOM 3295 CD1 TYR B 184 8.557 -59.098 29.990 1.00101.32 C +ATOM 3296 CD2 TYR B 184 7.724 -57.123 30.993 1.00 81.85 C +ATOM 3297 CE1 TYR B 184 8.030 -58.708 28.776 1.00111.55 C +ATOM 3298 CE2 TYR B 184 7.212 -56.712 29.776 1.00 95.34 C +ATOM 3299 CZ TYR B 184 7.358 -57.511 28.672 1.00102.16 C +ATOM 3300 OH TYR B 184 6.804 -57.120 27.465 1.00112.97 O +ATOM 3301 N GLU B 185 11.564 -60.399 32.045 1.00 94.79 N +ATOM 3302 CA GLU B 185 12.453 -61.317 31.376 1.00118.45 C +ATOM 3303 C GLU B 185 11.795 -62.687 31.294 1.00112.98 C +ATOM 3304 O GLU B 185 11.681 -63.387 32.291 1.00121.61 O +ATOM 3305 CB GLU B 185 13.800 -61.338 32.133 1.00128.77 C +ATOM 3306 CG GLU B 185 14.825 -62.388 31.731 1.00119.04 C +ATOM 3307 CD GLU B 185 16.183 -62.128 32.375 1.00121.19 C +ATOM 3308 OE1 GLU B 185 16.327 -61.115 33.093 1.00116.50 O +ATOM 3309 OE2 GLU B 185 17.100 -62.946 32.177 1.00120.00 O +ATOM 3310 N VAL B 186 11.436 -63.075 30.078 1.00109.32 N +ATOM 3311 CA VAL B 186 10.878 -64.392 29.812 1.00113.61 C +ATOM 3312 C VAL B 186 11.916 -65.324 29.171 1.00120.69 C +ATOM 3313 O VAL B 186 12.711 -64.900 28.330 1.00 94.12 O +ATOM 3314 CB VAL B 186 9.678 -64.274 28.874 1.00135.68 C +ATOM 3315 CG1 VAL B 186 8.948 -65.604 28.765 1.00134.49 C +ATOM 3316 CG2 VAL B 186 8.734 -63.182 29.362 1.00148.37 C +ATOM 3317 N GLN B 187 11.933 -66.581 29.608 1.00135.48 N +ATOM 3318 CA GLN B 187 12.939 -67.542 29.147 1.00137.04 C +ATOM 3319 C GLN B 187 12.395 -68.962 29.121 1.00117.57 C +ATOM 3320 O GLN B 187 11.708 -69.380 30.049 1.00 93.70 O +ATOM 3321 CB GLN B 187 14.164 -67.521 30.078 1.00141.40 C +ATOM 3322 CG GLN B 187 15.239 -66.488 29.769 1.00150.27 C +ATOM 3323 CD GLN B 187 16.227 -66.319 30.942 1.00157.42 C +ATOM 3324 OE1 GLN B 187 17.029 -65.363 31.009 1.00210.85 O +ATOM 3325 NE2 GLN B 187 16.185 -67.275 31.871 1.00139.12 N +ATOM 3326 N ALA B 188 12.717 -69.691 28.059 1.00122.07 N +ATOM 3327 CA ALA B 188 12.335 -71.092 27.955 1.00125.67 C +ATOM 3328 C ALA B 188 13.441 -71.884 27.286 1.00122.25 C +ATOM 3329 O ALA B 188 14.072 -71.416 26.334 1.00 97.83 O +ATOM 3330 CB ALA B 188 11.037 -71.237 27.176 1.00147.91 C +ATOM 3331 N GLY B 189 13.688 -73.081 27.794 1.00124.24 N +ATOM 3332 CA GLY B 189 14.768 -73.911 27.278 1.00139.14 C +ATOM 3333 C GLY B 189 14.458 -75.391 27.346 1.00147.08 C +ATOM 3334 O GLY B 189 13.890 -75.865 28.331 1.00134.94 O +ATOM 3335 N VAL B 190 14.836 -76.116 26.297 1.00159.78 N +ATOM 3336 CA VAL B 190 14.678 -77.561 26.262 1.00166.95 C +ATOM 3337 C VAL B 190 16.056 -78.232 26.220 1.00171.78 C +ATOM 3338 O VAL B 190 16.940 -77.814 25.462 1.00138.46 O +ATOM 3339 CB VAL B 190 13.833 -78.001 25.048 1.00163.97 C +ATOM 3340 CG1 VAL B 190 13.464 -79.470 25.167 1.00147.57 C +ATOM 3341 CG2 VAL B 190 12.580 -77.133 24.909 1.00153.62 C +ATOM 3342 N PHE B 191 16.232 -79.268 27.038 1.00188.84 N +ATOM 3343 CA PHE B 191 17.545 -79.899 27.235 1.00209.94 C +ATOM 3344 C PHE B 191 17.404 -81.436 27.252 1.00209.73 C +ATOM 3345 O PHE B 191 16.507 -81.967 27.877 1.00203.03 O +ATOM 3346 CB PHE B 191 18.132 -79.431 28.577 1.00217.22 C +ATOM 3347 CG PHE B 191 19.627 -79.592 28.690 1.00210.81 C +ATOM 3348 CD1 PHE B 191 20.192 -80.846 28.849 1.00183.08 C +ATOM 3349 CD2 PHE B 191 20.460 -78.485 28.679 1.00221.34 C +ATOM 3350 CE1 PHE B 191 21.563 -80.998 28.954 1.00175.84 C +ATOM 3351 CE2 PHE B 191 21.830 -78.629 28.812 1.00203.81 C +ATOM 3352 CZ PHE B 191 22.383 -79.890 28.940 1.00180.52 C +ATOM 3353 N ARG B 192 18.324 -82.160 26.615 1.00199.50 N +ATOM 3354 CA ARG B 192 18.302 -83.638 26.619 1.00197.98 C +ATOM 3355 C ARG B 192 19.669 -84.267 26.400 1.00178.63 C +ATOM 3356 O ARG B 192 19.806 -85.485 26.478 1.00163.68 O +ATOM 3357 CB ARG B 192 17.330 -84.191 25.571 1.00184.78 C +ATOM 3358 CG ARG B 192 16.079 -84.849 26.133 1.00172.02 C +ATOM 3359 CD ARG B 192 16.255 -85.468 27.526 1.00158.05 C +ATOM 3360 NE ARG B 192 15.004 -85.382 28.296 1.00160.00 N +ATOM 3361 CZ ARG B 192 14.076 -86.333 28.363 1.00172.81 C +ATOM 3362 NH1 ARG B 192 14.263 -87.492 27.753 1.00190.35 N +ATOM 3363 NH2 ARG B 192 12.962 -86.131 29.064 1.00178.15 N +ATOM 3364 N LEU B 200 20.933 -82.563 22.692 1.00145.21 N +ATOM 3365 CA LEU B 200 19.966 -81.551 22.273 1.00165.73 C +ATOM 3366 C LEU B 200 19.780 -80.482 23.343 1.00216.93 C +ATOM 3367 O LEU B 200 19.255 -80.756 24.431 1.00240.72 O +ATOM 3368 CB LEU B 200 18.601 -82.173 21.972 1.00148.02 C +ATOM 3369 CG LEU B 200 17.481 -81.147 21.733 1.00140.63 C +ATOM 3370 CD1 LEU B 200 17.227 -80.996 20.241 1.00134.49 C +ATOM 3371 CD2 LEU B 200 16.194 -81.477 22.492 1.00125.14 C +ATOM 3372 N GLU B 201 20.198 -79.261 23.021 1.00222.58 N +ATOM 3373 CA GLU B 201 19.761 -78.083 23.761 1.00185.80 C +ATOM 3374 C GLU B 201 19.056 -77.117 22.817 1.00157.59 C +ATOM 3375 O GLU B 201 19.406 -77.026 21.648 1.00135.18 O +ATOM 3376 CB GLU B 201 20.950 -77.391 24.435 1.00171.67 C +ATOM 3377 CG GLU B 201 20.529 -76.465 25.565 1.00176.06 C +ATOM 3378 CD GLU B 201 21.698 -75.770 26.249 1.00174.04 C +ATOM 3379 OE1 GLU B 201 22.668 -76.458 26.637 1.00164.53 O +ATOM 3380 OE2 GLU B 201 21.644 -74.533 26.411 1.00182.50 O +ATOM 3381 N GLY B 202 18.066 -76.400 23.336 1.00146.49 N +ATOM 3382 CA GLY B 202 17.418 -75.323 22.599 1.00164.00 C +ATOM 3383 C GLY B 202 16.831 -74.273 23.525 1.00179.02 C +ATOM 3384 O GLY B 202 16.077 -74.602 24.442 1.00206.41 O +ATOM 3385 N GLU B 203 17.196 -73.008 23.310 1.00162.85 N +ATOM 3386 CA GLU B 203 16.774 -71.929 24.198 1.00142.03 C +ATOM 3387 C GLU B 203 16.179 -70.728 23.464 1.00127.17 C +ATOM 3388 O GLU B 203 16.728 -70.260 22.468 1.00103.95 O +ATOM 3389 CB GLU B 203 17.948 -71.468 25.069 1.00146.82 C +ATOM 3390 CG GLU B 203 18.415 -72.528 26.072 1.00176.00 C +ATOM 3391 CD GLU B 203 19.514 -72.062 27.024 1.00182.08 C +ATOM 3392 OE1 GLU B 203 20.023 -70.935 26.838 1.00186.35 O +ATOM 3393 OE2 GLU B 203 19.862 -72.829 27.955 1.00160.10 O +ATOM 3394 N VAL B 204 15.074 -70.221 24.009 1.00117.28 N +ATOM 3395 CA VAL B 204 14.527 -68.930 23.625 1.00104.88 C +ATOM 3396 C VAL B 204 14.438 -68.015 24.838 1.00116.14 C +ATOM 3397 O VAL B 204 14.075 -68.437 25.949 1.00108.33 O +ATOM 3398 CB VAL B 204 13.134 -69.088 23.030 1.00107.75 C +ATOM 3399 CG1 VAL B 204 12.402 -67.753 22.958 1.00105.15 C +ATOM 3400 CG2 VAL B 204 13.245 -69.716 21.649 1.00126.86 C +ATOM 3401 N GLY B 205 14.880 -66.778 24.647 1.00131.69 N +ATOM 3402 CA GLY B 205 14.856 -65.780 25.711 1.00128.28 C +ATOM 3403 C GLY B 205 14.400 -64.435 25.181 1.00120.76 C +ATOM 3404 O GLY B 205 14.660 -64.098 24.015 1.00101.86 O +ATOM 3405 N TYR B 206 13.725 -63.669 26.034 1.00100.97 N +ATOM 3406 CA TYR B 206 13.297 -62.321 25.686 1.00112.89 C +ATOM 3407 C TYR B 206 13.270 -61.429 26.925 1.00112.65 C +ATOM 3408 O TYR B 206 12.884 -61.880 27.995 1.00115.99 O +ATOM 3409 CB TYR B 206 11.904 -62.360 25.047 1.00127.21 C +ATOM 3410 CG TYR B 206 11.357 -60.998 24.701 1.00140.89 C +ATOM 3411 CD1 TYR B 206 11.829 -60.293 23.598 1.00130.72 C +ATOM 3412 CD2 TYR B 206 10.395 -60.396 25.502 1.00155.57 C +ATOM 3413 CE1 TYR B 206 11.371 -59.022 23.303 1.00130.23 C +ATOM 3414 CE2 TYR B 206 9.922 -59.131 25.206 1.00152.01 C +ATOM 3415 CZ TYR B 206 10.420 -58.442 24.115 1.00126.38 C +ATOM 3416 OH TYR B 206 9.946 -57.180 23.835 1.00 93.64 O +ATOM 3417 N THR B 207 13.663 -60.164 26.774 1.00111.90 N +ATOM 3418 CA THR B 207 13.640 -59.208 27.887 1.00108.73 C +ATOM 3419 C THR B 207 13.156 -57.833 27.444 1.00 94.87 C +ATOM 3420 O THR B 207 13.517 -57.349 26.359 1.00 89.04 O +ATOM 3421 CB THR B 207 15.038 -59.029 28.511 1.00125.79 C +ATOM 3422 OG1 THR B 207 15.942 -58.503 27.532 1.00140.75 O +ATOM 3423 CG2 THR B 207 15.583 -60.346 29.010 1.00134.96 C +ATOM 3424 N SER B 208 12.336 -57.200 28.278 1.00 84.41 N +ATOM 3425 CA SER B 208 11.788 -55.884 27.940 1.00 89.42 C +ATOM 3426 C SER B 208 11.813 -54.916 29.112 1.00 67.34 C +ATOM 3427 O SER B 208 11.287 -55.219 30.178 1.00 40.42 O +ATOM 3428 CB SER B 208 10.343 -56.003 27.401 1.00100.90 C +ATOM 3429 OG SER B 208 9.757 -54.732 27.193 1.00 98.58 O +ATOM 3430 N ASN B 209 12.354 -53.730 28.850 1.00 75.73 N +ATOM 3431 CA ASN B 209 12.342 -52.620 29.798 1.00 90.26 C +ATOM 3432 C ASN B 209 11.526 -51.488 29.229 1.00 86.55 C +ATOM 3433 O ASN B 209 11.653 -51.138 28.041 1.00 99.13 O +ATOM 3434 CB ASN B 209 13.757 -52.054 30.050 1.00 91.20 C +ATOM 3435 CG ASN B 209 14.637 -52.954 30.872 1.00 98.37 C +ATOM 3436 OD1 ASN B 209 14.488 -53.056 32.087 1.00101.27 O +ATOM 3437 ND2 ASN B 209 15.516 -53.679 30.196 1.00123.05 N +ATOM 3438 N GLU B 210 10.722 -50.873 30.082 1.00 93.32 N +ATOM 3439 CA GLU B 210 10.076 -49.610 29.714 1.00108.81 C +ATOM 3440 C GLU B 210 11.144 -48.534 29.660 1.00 94.45 C +ATOM 3441 O GLU B 210 12.077 -48.564 30.436 1.00 95.85 O +ATOM 3442 CB GLU B 210 9.010 -49.228 30.743 1.00119.78 C +ATOM 3443 CG GLU B 210 7.701 -48.695 30.163 1.00116.57 C +ATOM 3444 CD GLU B 210 6.550 -48.740 31.169 1.00102.23 C +ATOM 3445 OE1 GLU B 210 6.571 -49.566 32.131 1.00 64.58 O +ATOM 3446 OE2 GLU B 210 5.653 -47.891 31.027 1.00 84.39 O +ATOM 3447 N PRO B 211 11.059 -47.626 28.680 1.00115.62 N +ATOM 3448 CA PRO B 211 11.981 -46.504 28.681 1.00112.98 C +ATOM 3449 C PRO B 211 11.645 -45.514 29.793 1.00 97.54 C +ATOM 3450 O PRO B 211 10.505 -45.046 29.905 1.00 63.25 O +ATOM 3451 CB PRO B 211 11.776 -45.869 27.302 1.00128.84 C +ATOM 3452 CG PRO B 211 11.106 -46.905 26.476 1.00140.55 C +ATOM 3453 CD PRO B 211 10.249 -47.660 27.450 1.00148.47 C +ATOM 3454 N VAL B 212 12.636 -45.244 30.636 1.00 94.23 N +ATOM 3455 CA VAL B 212 12.479 -44.305 31.736 1.00 91.43 C +ATOM 3456 C VAL B 212 12.149 -42.940 31.111 1.00 87.60 C +ATOM 3457 O VAL B 212 11.356 -42.153 31.657 1.00 58.67 O +ATOM 3458 CB VAL B 212 13.771 -44.233 32.620 1.00 82.77 C +ATOM 3459 CG1 VAL B 212 13.538 -43.324 33.829 1.00 79.39 C +ATOM 3460 CG2 VAL B 212 14.231 -45.625 33.054 1.00 62.95 C +ATOM 3461 N MET B 213 12.851 -42.657 30.011 1.00 89.98 N +ATOM 3462 CA MET B 213 12.652 -41.451 29.212 1.00 94.88 C +ATOM 3463 C MET B 213 11.240 -41.216 28.747 1.00 86.55 C +ATOM 3464 O MET B 213 10.890 -40.096 28.435 1.00 46.64 O +ATOM 3465 CB MET B 213 13.596 -41.445 28.085 1.00100.20 C +ATOM 3466 CG MET B 213 12.910 -41.542 26.793 1.00 83.69 C +ATOM 3467 SD MET B 213 14.182 -41.653 25.554 1.00 59.62 S +ATOM 3468 CE MET B 213 12.989 -41.832 24.229 1.00 84.79 C +ATOM 3469 N LEU B 214 10.486 -42.307 28.594 1.00102.91 N +ATOM 3470 CA LEU B 214 9.116 -42.245 28.076 1.00 99.96 C +ATOM 3471 C LEU B 214 8.115 -42.168 29.228 1.00100.65 C +ATOM 3472 O LEU B 214 7.047 -41.544 29.106 1.00 97.19 O +ATOM 3473 CB LEU B 214 8.827 -43.474 27.211 1.00 84.97 C +ATOM 3474 CG LEU B 214 8.104 -43.286 25.884 1.00 85.06 C +ATOM 3475 CD1 LEU B 214 8.851 -42.379 24.924 1.00 71.62 C +ATOM 3476 CD2 LEU B 214 7.864 -44.655 25.240 1.00 95.24 C +ATOM 3477 N CYS B 215 8.488 -42.757 30.363 1.00 86.25 N +ATOM 3478 CA CYS B 215 7.689 -42.654 31.586 1.00 93.12 C +ATOM 3479 C CYS B 215 7.746 -41.248 32.192 1.00108.09 C +ATOM 3480 O CYS B 215 6.721 -40.691 32.659 1.00107.99 O +ATOM 3481 CB CYS B 215 8.200 -43.631 32.626 1.00 87.01 C +ATOM 3482 SG CYS B 215 8.040 -45.344 32.135 1.00 84.18 S +ATOM 3483 N LEU B 216 8.952 -40.678 32.191 1.00 98.40 N +ATOM 3484 CA LEU B 216 9.114 -39.299 32.578 1.00 84.06 C +ATOM 3485 C LEU B 216 8.165 -38.412 31.738 1.00 61.55 C +ATOM 3486 O LEU B 216 7.451 -37.556 32.275 1.00 44.81 O +ATOM 3487 CB LEU B 216 10.571 -38.868 32.429 1.00 83.46 C +ATOM 3488 CG LEU B 216 10.864 -37.401 32.800 1.00 98.15 C +ATOM 3489 CD1 LEU B 216 10.454 -37.057 34.220 1.00 95.66 C +ATOM 3490 CD2 LEU B 216 12.343 -37.084 32.606 1.00 96.62 C +ATOM 3491 N MET B 217 8.173 -38.627 30.432 1.00 56.27 N +ATOM 3492 CA MET B 217 7.441 -37.761 29.523 1.00 80.81 C +ATOM 3493 C MET B 217 5.963 -37.875 29.852 1.00 77.14 C +ATOM 3494 O MET B 217 5.260 -36.864 29.948 1.00 90.32 O +ATOM 3495 CB MET B 217 7.752 -38.106 28.018 1.00 94.99 C +ATOM 3496 CG MET B 217 7.924 -36.874 27.136 1.00 99.35 C +ATOM 3497 SD MET B 217 6.379 -35.950 26.907 1.00 71.06 S +ATOM 3498 CE MET B 217 6.927 -34.448 26.111 1.00101.73 C +ATOM 3499 N SER B 218 5.501 -39.113 29.989 1.00 85.73 N +ATOM 3500 CA SER B 218 4.086 -39.405 30.279 1.00 90.68 C +ATOM 3501 C SER B 218 3.634 -38.690 31.553 1.00 95.86 C +ATOM 3502 O SER B 218 2.616 -37.997 31.566 1.00 89.33 O +ATOM 3503 CB SER B 218 3.891 -40.919 30.441 1.00 77.47 C +ATOM 3504 OG SER B 218 2.524 -41.230 30.532 1.00 66.75 O +ATOM 3505 N ALA B 219 4.443 -38.806 32.599 1.00 92.31 N +ATOM 3506 CA ALA B 219 4.084 -38.252 33.893 1.00 97.67 C +ATOM 3507 C ALA B 219 4.034 -36.717 33.875 1.00 88.07 C +ATOM 3508 O ALA B 219 3.190 -36.093 34.533 1.00 95.11 O +ATOM 3509 CB ALA B 219 5.063 -38.746 34.943 1.00116.24 C +ATOM 3510 N ILE B 220 4.908 -36.112 33.086 1.00 78.29 N +ATOM 3511 CA ILE B 220 4.909 -34.654 32.950 1.00 80.10 C +ATOM 3512 C ILE B 220 3.640 -34.163 32.249 1.00 85.90 C +ATOM 3513 O ILE B 220 3.045 -33.167 32.648 1.00 78.51 O +ATOM 3514 CB ILE B 220 6.173 -34.150 32.194 1.00 74.06 C +ATOM 3515 CG1 ILE B 220 7.420 -34.380 33.085 1.00 82.64 C +ATOM 3516 CG2 ILE B 220 6.043 -32.674 31.815 1.00 46.93 C +ATOM 3517 CD1 ILE B 220 8.736 -34.311 32.354 1.00 75.37 C +ATOM 3518 N GLU B 221 3.233 -34.864 31.199 1.00 90.80 N +ATOM 3519 CA GLU B 221 1.984 -34.542 30.511 1.00 84.19 C +ATOM 3520 C GLU B 221 0.825 -34.560 31.504 1.00 81.30 C +ATOM 3521 O GLU B 221 0.020 -33.629 31.565 1.00 75.18 O +ATOM 3522 CB GLU B 221 1.747 -35.547 29.367 1.00107.10 C +ATOM 3523 CG GLU B 221 2.661 -35.327 28.168 1.00137.48 C +ATOM 3524 CD GLU B 221 2.745 -36.524 27.222 1.00163.64 C +ATOM 3525 OE1 GLU B 221 2.706 -37.702 27.686 1.00 91.53 O +ATOM 3526 OE2 GLU B 221 2.848 -36.261 25.995 1.00194.32 O +ATOM 3527 N THR B 222 0.717 -35.675 32.229 1.00 93.28 N +ATOM 3528 CA THR B 222 -0.328 -35.893 33.228 1.00 81.83 C +ATOM 3529 C THR B 222 -0.369 -34.727 34.190 1.00 74.88 C +ATOM 3530 O THR B 222 -1.440 -34.187 34.499 1.00 88.60 O +ATOM 3531 CB THR B 222 -0.043 -37.192 34.027 1.00 77.42 C +ATOM 3532 OG1 THR B 222 -0.302 -38.348 33.208 1.00 54.67 O +ATOM 3533 CG2 THR B 222 -0.881 -37.242 35.316 1.00 89.81 C +ATOM 3534 N GLY B 223 0.801 -34.361 34.685 1.00 70.92 N +ATOM 3535 CA GLY B 223 0.925 -33.199 35.554 1.00 98.50 C +ATOM 3536 C GLY B 223 0.352 -31.929 34.926 1.00 84.38 C +ATOM 3537 O GLY B 223 -0.255 -31.101 35.635 1.00 73.03 O +ATOM 3538 N VAL B 224 0.605 -31.733 33.627 1.00 62.55 N +ATOM 3539 CA VAL B 224 0.178 -30.516 32.971 1.00 68.02 C +ATOM 3540 C VAL B 224 -1.335 -30.486 32.958 1.00 81.06 C +ATOM 3541 O VAL B 224 -1.949 -29.446 33.201 1.00 88.36 O +ATOM 3542 CB VAL B 224 0.711 -30.431 31.545 1.00 78.85 C +ATOM 3543 CG1 VAL B 224 0.061 -29.269 30.811 1.00 83.40 C +ATOM 3544 CG2 VAL B 224 2.230 -30.270 31.547 1.00 91.98 C +ATOM 3545 N ILE B 225 -1.944 -31.641 32.709 1.00108.91 N +ATOM 3546 CA ILE B 225 -3.407 -31.738 32.712 1.00 99.32 C +ATOM 3547 C ILE B 225 -3.976 -31.374 34.079 1.00 94.98 C +ATOM 3548 O ILE B 225 -4.833 -30.494 34.169 1.00 80.05 O +ATOM 3549 CB ILE B 225 -3.896 -33.137 32.311 1.00 83.51 C +ATOM 3550 CG1 ILE B 225 -3.581 -33.394 30.840 1.00 87.56 C +ATOM 3551 CG2 ILE B 225 -5.398 -33.241 32.519 1.00 95.37 C +ATOM 3552 CD1 ILE B 225 -3.635 -34.855 30.456 1.00 96.98 C +ATOM 3553 N PHE B 226 -3.473 -32.021 35.132 1.00 95.96 N +ATOM 3554 CA PHE B 226 -3.898 -31.713 36.502 1.00101.65 C +ATOM 3555 C PHE B 226 -3.733 -30.216 36.830 1.00 92.97 C +ATOM 3556 O PHE B 226 -4.528 -29.658 37.597 1.00121.85 O +ATOM 3557 CB PHE B 226 -3.135 -32.557 37.542 1.00 99.09 C +ATOM 3558 CG PHE B 226 -3.646 -33.968 37.689 1.00 91.84 C +ATOM 3559 CD1 PHE B 226 -4.947 -34.217 38.069 1.00 96.20 C +ATOM 3560 CD2 PHE B 226 -2.791 -35.052 37.500 1.00 97.26 C +ATOM 3561 CE1 PHE B 226 -5.404 -35.520 38.203 1.00 98.44 C +ATOM 3562 CE2 PHE B 226 -3.234 -36.356 37.665 1.00 76.11 C +ATOM 3563 CZ PHE B 226 -4.543 -36.588 37.995 1.00 83.49 C +ATOM 3564 N LEU B 227 -2.709 -29.581 36.270 1.00 60.03 N +ATOM 3565 CA LEU B 227 -2.488 -28.171 36.496 1.00 62.42 C +ATOM 3566 C LEU B 227 -3.572 -27.350 35.841 1.00 62.02 C +ATOM 3567 O LEU B 227 -4.076 -26.394 36.427 1.00 54.61 O +ATOM 3568 CB LEU B 227 -1.110 -27.779 35.962 1.00 84.35 C +ATOM 3569 CG LEU B 227 0.099 -28.142 36.850 1.00101.25 C +ATOM 3570 CD1 LEU B 227 1.453 -28.024 36.187 1.00122.66 C +ATOM 3571 CD2 LEU B 227 0.110 -27.336 38.126 1.00 96.35 C +ATOM 3572 N ILE B 228 -3.923 -27.708 34.614 1.00 76.00 N +ATOM 3573 CA ILE B 228 -4.930 -26.954 33.858 1.00 93.89 C +ATOM 3574 C ILE B 228 -6.283 -27.095 34.533 1.00 92.27 C +ATOM 3575 O ILE B 228 -6.982 -26.116 34.764 1.00 65.43 O +ATOM 3576 CB ILE B 228 -5.062 -27.436 32.389 1.00 98.35 C +ATOM 3577 CG1 ILE B 228 -3.773 -27.168 31.605 1.00103.03 C +ATOM 3578 CG2 ILE B 228 -6.190 -26.699 31.701 1.00102.18 C +ATOM 3579 CD1 ILE B 228 -3.665 -27.915 30.294 1.00 85.68 C +ATOM 3580 N ASN B 229 -6.634 -28.333 34.857 1.00100.93 N +ATOM 3581 CA ASN B 229 -7.894 -28.613 35.529 1.00108.14 C +ATOM 3582 C ASN B 229 -7.982 -27.849 36.851 1.00113.30 C +ATOM 3583 O ASN B 229 -9.016 -27.267 37.178 1.00117.23 O +ATOM 3584 CB ASN B 229 -8.041 -30.121 35.765 1.00112.29 C +ATOM 3585 CG ASN B 229 -9.450 -30.519 36.119 1.00109.70 C +ATOM 3586 OD1 ASN B 229 -10.418 -29.856 35.717 1.00137.91 O +ATOM 3587 ND2 ASN B 229 -9.588 -31.671 36.771 1.00 93.31 N +ATOM 3588 N ASP B 230 -6.882 -27.857 37.605 1.00126.38 N +ATOM 3589 CA ASP B 230 -6.810 -27.178 38.900 1.00117.15 C +ATOM 3590 C ASP B 230 -6.973 -25.677 38.727 1.00 90.33 C +ATOM 3591 O ASP B 230 -7.728 -25.039 39.478 1.00 98.78 O +ATOM 3592 CB ASP B 230 -5.474 -27.461 39.586 1.00120.52 C +ATOM 3593 CG ASP B 230 -5.402 -26.871 40.981 1.00145.04 C +ATOM 3594 OD1 ASP B 230 -6.063 -27.423 41.882 1.00213.27 O +ATOM 3595 OD2 ASP B 230 -4.719 -25.859 41.184 1.00147.68 O +ATOM 3596 N GLY B 231 -6.357 -25.150 37.683 1.00 71.45 N +ATOM 3597 CA GLY B 231 -6.508 -23.752 37.371 1.00 98.69 C +ATOM 3598 C GLY B 231 -7.917 -23.356 36.926 1.00114.90 C +ATOM 3599 O GLY B 231 -8.408 -22.251 37.249 1.00 96.95 O +ATOM 3600 N ILE B 232 -8.588 -24.264 36.218 1.00123.91 N +ATOM 3601 CA ILE B 232 -10.000 -24.064 35.837 1.00118.92 C +ATOM 3602 C ILE B 232 -10.913 -23.954 37.062 1.00 90.77 C +ATOM 3603 O ILE B 232 -11.648 -22.986 37.196 1.00 64.52 O +ATOM 3604 CB ILE B 232 -10.512 -25.216 34.940 1.00131.20 C +ATOM 3605 CG1 ILE B 232 -9.885 -25.099 33.546 1.00135.02 C +ATOM 3606 CG2 ILE B 232 -12.041 -25.212 34.859 1.00132.10 C +ATOM 3607 CD1 ILE B 232 -9.974 -26.366 32.728 1.00132.45 C +ATOM 3608 N ASP B 233 -10.809 -24.928 37.967 1.00 86.02 N +ATOM 3609 CA ASP B 233 -11.510 -24.891 39.257 1.00 84.92 C +ATOM 3610 C ASP B 233 -11.258 -23.578 40.013 1.00100.06 C +ATOM 3611 O ASP B 233 -12.188 -22.947 40.488 1.00 84.13 O +ATOM 3612 CB ASP B 233 -11.088 -26.082 40.147 1.00101.08 C +ATOM 3613 CG ASP B 233 -11.480 -27.434 39.557 1.00107.96 C +ATOM 3614 OD1 ASP B 233 -11.876 -27.467 38.365 1.00122.37 O +ATOM 3615 OD2 ASP B 233 -11.314 -28.460 40.257 1.00 70.42 O +ATOM 3616 N ARG B 234 -9.988 -23.178 40.143 1.00112.96 N +ATOM 3617 CA ARG B 234 -9.614 -22.048 41.004 1.00 95.90 C +ATOM 3618 C ARG B 234 -9.805 -20.686 40.341 1.00 90.80 C +ATOM 3619 O ARG B 234 -9.522 -19.654 40.949 1.00105.47 O +ATOM 3620 CB ARG B 234 -8.167 -22.221 41.501 1.00 98.04 C +ATOM 3621 CG ARG B 234 -8.042 -23.289 42.571 1.00 79.23 C +ATOM 3622 CD ARG B 234 -6.644 -23.817 42.690 1.00 75.74 C +ATOM 3623 NE ARG B 234 -6.653 -24.886 43.669 1.00 96.76 N +ATOM 3624 CZ ARG B 234 -5.898 -24.917 44.762 1.00124.85 C +ATOM 3625 NH1 ARG B 234 -5.047 -23.932 45.006 1.00159.94 N +ATOM 3626 NH2 ARG B 234 -5.970 -25.951 45.603 1.00113.96 N +ATOM 3627 N GLY B 235 -10.227 -20.682 39.083 1.00 92.00 N +ATOM 3628 CA GLY B 235 -10.481 -19.434 38.373 1.00 96.13 C +ATOM 3629 C GLY B 235 -9.218 -18.714 37.926 1.00112.84 C +ATOM 3630 O GLY B 235 -9.196 -17.486 37.864 1.00108.47 O +ATOM 3631 N LEU B 236 -8.166 -19.467 37.582 1.00136.07 N +ATOM 3632 CA LEU B 236 -6.988 -18.870 36.900 1.00114.38 C +ATOM 3633 C LEU B 236 -7.342 -18.584 35.452 1.00112.53 C +ATOM 3634 O LEU B 236 -7.122 -17.481 34.951 1.00128.20 O +ATOM 3635 CB LEU B 236 -5.762 -19.787 36.936 1.00110.73 C +ATOM 3636 CG LEU B 236 -4.883 -19.756 38.195 1.00120.79 C +ATOM 3637 CD1 LEU B 236 -5.526 -20.568 39.313 1.00143.17 C +ATOM 3638 CD2 LEU B 236 -3.504 -20.316 37.880 1.00135.15 C +ATOM 3639 N TRP B 237 -7.949 -19.568 34.797 1.00124.41 N +ATOM 3640 CA TRP B 237 -8.338 -19.441 33.392 1.00135.23 C +ATOM 3641 C TRP B 237 -9.719 -20.081 33.152 1.00127.43 C +ATOM 3642 O TRP B 237 -10.212 -20.839 33.986 1.00 99.55 O +ATOM 3643 CB TRP B 237 -7.262 -20.066 32.494 1.00124.27 C +ATOM 3644 CG TRP B 237 -6.600 -21.255 33.114 1.00109.25 C +ATOM 3645 CD1 TRP B 237 -7.176 -22.461 33.386 1.00106.23 C +ATOM 3646 CD2 TRP B 237 -5.254 -21.338 33.582 1.00 86.89 C +ATOM 3647 NE1 TRP B 237 -6.270 -23.292 33.984 1.00109.26 N +ATOM 3648 CE2 TRP B 237 -5.072 -22.637 34.095 1.00104.54 C +ATOM 3649 CE3 TRP B 237 -4.181 -20.451 33.606 1.00 79.73 C +ATOM 3650 CZ2 TRP B 237 -3.854 -23.068 34.633 1.00100.22 C +ATOM 3651 CZ3 TRP B 237 -2.969 -20.886 34.140 1.00 91.75 C +ATOM 3652 CH2 TRP B 237 -2.824 -22.175 34.659 1.00 89.19 C +ATOM 3653 N ASP B 238 -10.324 -19.767 32.010 1.00120.70 N +ATOM 3654 CA ASP B 238 -11.695 -20.181 31.719 1.00112.03 C +ATOM 3655 C ASP B 238 -11.855 -20.854 30.359 1.00102.09 C +ATOM 3656 O ASP B 238 -11.136 -20.543 29.401 1.00104.91 O +ATOM 3657 CB ASP B 238 -12.630 -18.987 31.789 1.00123.84 C +ATOM 3658 CG ASP B 238 -12.573 -18.286 33.133 1.00131.93 C +ATOM 3659 OD1 ASP B 238 -11.638 -17.478 33.323 1.00121.36 O +ATOM 3660 OD2 ASP B 238 -13.482 -18.498 33.972 1.00132.76 O +ATOM 3661 N LEU B 239 -12.794 -21.793 30.294 1.00 88.70 N +ATOM 3662 CA LEU B 239 -13.051 -22.549 29.080 1.00 93.90 C +ATOM 3663 C LEU B 239 -13.810 -21.693 28.076 1.00100.33 C +ATOM 3664 O LEU B 239 -14.656 -20.881 28.449 1.00 98.94 O +ATOM 3665 CB LEU B 239 -13.859 -23.817 29.393 1.00101.91 C +ATOM 3666 CG LEU B 239 -13.163 -25.030 30.019 1.00109.74 C +ATOM 3667 CD1 LEU B 239 -14.124 -26.205 30.142 1.00104.61 C +ATOM 3668 CD2 LEU B 239 -11.958 -25.433 29.200 1.00122.27 C +ATOM 3669 N GLN B 240 -13.515 -21.907 26.799 1.00108.59 N +ATOM 3670 CA GLN B 240 -14.300 -21.326 25.723 1.00115.55 C +ATOM 3671 C GLN B 240 -15.774 -21.694 25.894 1.00133.39 C +ATOM 3672 O GLN B 240 -16.643 -20.826 25.963 1.00125.36 O +ATOM 3673 CB GLN B 240 -13.779 -21.822 24.362 1.00115.61 C +ATOM 3674 CG GLN B 240 -14.406 -21.114 23.172 1.00129.67 C +ATOM 3675 CD GLN B 240 -14.045 -19.635 23.139 1.00145.15 C +ATOM 3676 OE1 GLN B 240 -12.964 -19.259 22.683 1.00147.56 O +ATOM 3677 NE2 GLN B 240 -14.948 -18.788 23.632 1.00151.32 N +ATOM 3678 N ASN B 241 -16.034 -22.995 25.952 1.00163.52 N +ATOM 3679 CA ASN B 241 -17.383 -23.526 26.126 1.00156.13 C +ATOM 3680 C ASN B 241 -17.586 -24.022 27.542 1.00155.39 C +ATOM 3681 O ASN B 241 -17.021 -25.061 27.933 1.00161.49 O +ATOM 3682 CB ASN B 241 -17.616 -24.685 25.161 1.00163.37 C +ATOM 3683 CG ASN B 241 -18.414 -24.272 23.956 1.00161.48 C +ATOM 3684 OD1 ASN B 241 -19.604 -24.557 23.871 1.00134.76 O +ATOM 3685 ND2 ASN B 241 -17.763 -23.594 23.007 1.00192.98 N +ATOM 3686 N LYS B 242 -18.411 -23.303 28.295 1.00119.23 N +ATOM 3687 CA LYS B 242 -18.691 -23.682 29.669 1.00116.45 C +ATOM 3688 C LYS B 242 -19.411 -25.029 29.696 1.00126.95 C +ATOM 3689 O LYS B 242 -19.322 -25.786 30.677 1.00105.42 O +ATOM 3690 CB LYS B 242 -19.513 -22.596 30.357 1.00110.16 C +ATOM 3691 CG LYS B 242 -18.947 -21.196 30.173 1.00 99.18 C +ATOM 3692 CD LYS B 242 -18.731 -20.492 31.503 1.00114.14 C +ATOM 3693 CE LYS B 242 -17.361 -19.837 31.560 1.00122.93 C +ATOM 3694 NZ LYS B 242 -17.172 -19.005 32.779 1.00137.29 N +ATOM 3695 N ALA B 243 -20.100 -25.321 28.589 1.00158.27 N +ATOM 3696 CA ALA B 243 -20.767 -26.604 28.363 1.00165.16 C +ATOM 3697 C ALA B 243 -19.770 -27.754 28.330 1.00160.44 C +ATOM 3698 O ALA B 243 -20.163 -28.919 28.495 1.00184.16 O +ATOM 3699 CB ALA B 243 -21.559 -26.568 27.057 1.00150.00 C +ATOM 3700 N GLU B 244 -18.492 -27.439 28.110 1.00132.58 N +ATOM 3701 CA GLU B 244 -17.477 -28.478 28.004 1.00136.40 C +ATOM 3702 C GLU B 244 -16.791 -28.744 29.331 1.00110.32 C +ATOM 3703 O GLU B 244 -15.804 -29.471 29.362 1.00138.93 O +ATOM 3704 CB GLU B 244 -16.435 -28.125 26.943 1.00144.35 C +ATOM 3705 CG GLU B 244 -16.935 -28.248 25.512 1.00148.42 C +ATOM 3706 CD GLU B 244 -15.821 -28.144 24.490 1.00155.19 C +ATOM 3707 OE1 GLU B 244 -15.341 -27.012 24.236 1.00192.61 O +ATOM 3708 OE2 GLU B 244 -15.416 -29.194 23.945 1.00140.05 O +ATOM 3709 N ARG B 245 -17.328 -28.205 30.422 1.00 98.87 N +ATOM 3710 CA ARG B 245 -16.838 -28.554 31.759 1.00138.20 C +ATOM 3711 C ARG B 245 -16.857 -30.053 32.058 1.00148.20 C +ATOM 3712 O ARG B 245 -15.960 -30.565 32.732 1.00167.54 O +ATOM 3713 CB ARG B 245 -17.615 -27.844 32.855 1.00151.70 C +ATOM 3714 CG ARG B 245 -16.994 -28.016 34.244 1.00150.67 C +ATOM 3715 CD ARG B 245 -17.729 -27.206 35.322 1.00173.13 C +ATOM 3716 NE ARG B 245 -17.051 -25.933 35.584 1.00192.84 N +ATOM 3717 CZ ARG B 245 -15.882 -25.810 36.214 1.00181.36 C +ATOM 3718 NH1 ARG B 245 -15.224 -26.878 36.626 1.00169.11 N +ATOM 3719 NH2 ARG B 245 -15.355 -24.609 36.417 1.00194.93 N +ATOM 3720 N GLN B 246 -17.877 -30.756 31.571 1.00148.22 N +ATOM 3721 CA GLN B 246 -18.021 -32.184 31.864 1.00154.20 C +ATOM 3722 C GLN B 246 -17.382 -33.057 30.788 1.00156.31 C +ATOM 3723 O GLN B 246 -17.733 -34.225 30.634 1.00176.47 O +ATOM 3724 CB GLN B 246 -19.497 -32.543 32.050 1.00155.96 C +ATOM 3725 CG GLN B 246 -20.116 -31.861 33.263 1.00159.89 C +ATOM 3726 CD GLN B 246 -19.707 -32.461 34.603 1.00183.30 C +ATOM 3727 OE1 GLN B 246 -18.526 -32.680 34.873 1.00179.02 O +ATOM 3728 NE2 GLN B 246 -20.688 -32.670 35.477 1.00213.40 N +ATOM 3729 N ASN B 247 -16.452 -32.470 30.040 1.00148.80 N +ATOM 3730 CA ASN B 247 -15.564 -33.207 29.137 1.00147.63 C +ATOM 3731 C ASN B 247 -15.054 -34.505 29.768 1.00149.72 C +ATOM 3732 O ASN B 247 -14.701 -34.527 30.949 1.00152.55 O +ATOM 3733 CB ASN B 247 -14.364 -32.323 28.785 1.00137.53 C +ATOM 3734 CG ASN B 247 -13.743 -32.667 27.458 1.00127.23 C +ATOM 3735 OD1 ASN B 247 -12.654 -33.254 27.398 1.00120.26 O +ATOM 3736 ND2 ASN B 247 -14.442 -32.327 26.380 1.00131.05 N +ATOM 3737 N ASP B 248 -15.034 -35.585 28.983 1.00156.87 N +ATOM 3738 CA ASP B 248 -14.634 -36.919 29.481 1.00164.42 C +ATOM 3739 C ASP B 248 -13.280 -36.869 30.189 1.00157.34 C +ATOM 3740 O ASP B 248 -13.095 -37.436 31.273 1.00171.51 O +ATOM 3741 CB ASP B 248 -14.546 -37.927 28.325 1.00154.58 C +ATOM 3742 CG ASP B 248 -15.907 -38.313 27.768 1.00150.85 C +ATOM 3743 OD1 ASP B 248 -16.863 -38.465 28.550 1.00146.48 O +ATOM 3744 OD2 ASP B 248 -16.011 -38.487 26.537 1.00162.02 O +ATOM 3745 N ILE B 249 -12.335 -36.192 29.549 1.00147.54 N +ATOM 3746 CA ILE B 249 -10.973 -36.122 30.038 1.00144.61 C +ATOM 3747 C ILE B 249 -10.943 -35.321 31.339 1.00127.33 C +ATOM 3748 O ILE B 249 -10.376 -35.771 32.351 1.00171.43 O +ATOM 3749 CB ILE B 249 -10.041 -35.481 28.983 1.00144.60 C +ATOM 3750 CG1 ILE B 249 -9.987 -36.354 27.716 1.00130.01 C +ATOM 3751 CG2 ILE B 249 -8.635 -35.315 29.544 1.00164.30 C +ATOM 3752 CD1 ILE B 249 -9.527 -35.620 26.477 1.00114.15 C +ATOM 3753 N LEU B 250 -11.568 -34.149 31.313 1.00 91.80 N +ATOM 3754 CA LEU B 250 -11.563 -33.261 32.470 1.00102.34 C +ATOM 3755 C LEU B 250 -12.184 -33.905 33.710 1.00126.01 C +ATOM 3756 O LEU B 250 -11.716 -33.692 34.834 1.00111.79 O +ATOM 3757 CB LEU B 250 -12.290 -31.958 32.147 1.00 90.53 C +ATOM 3758 CG LEU B 250 -11.461 -30.930 31.373 1.00 87.69 C +ATOM 3759 CD1 LEU B 250 -12.317 -29.788 30.833 1.00 74.39 C +ATOM 3760 CD2 LEU B 250 -10.353 -30.373 32.252 1.00 88.21 C +ATOM 3761 N VAL B 251 -13.253 -34.671 33.507 1.00155.46 N +ATOM 3762 CA VAL B 251 -13.914 -35.359 34.623 1.00163.90 C +ATOM 3763 C VAL B 251 -13.111 -36.577 35.081 1.00156.44 C +ATOM 3764 O VAL B 251 -13.239 -37.020 36.227 1.00156.12 O +ATOM 3765 CB VAL B 251 -15.371 -35.775 34.285 1.00143.99 C +ATOM 3766 CG1 VAL B 251 -16.177 -34.560 33.828 1.00126.29 C +ATOM 3767 CG2 VAL B 251 -15.409 -36.893 33.248 1.00129.80 C +ATOM 3768 N LYS B 252 -12.310 -37.130 34.177 1.00132.43 N +ATOM 3769 CA LYS B 252 -11.453 -38.262 34.513 1.00137.11 C +ATOM 3770 C LYS B 252 -10.355 -37.817 35.484 1.00156.24 C +ATOM 3771 O LYS B 252 -10.116 -38.461 36.515 1.00178.47 O +ATOM 3772 CB LYS B 252 -10.868 -38.849 33.230 1.00133.05 C +ATOM 3773 CG LYS B 252 -9.912 -40.012 33.422 1.00128.44 C +ATOM 3774 CD LYS B 252 -9.375 -40.477 32.072 1.00141.98 C +ATOM 3775 CE LYS B 252 -7.862 -40.657 32.102 1.00160.92 C +ATOM 3776 NZ LYS B 252 -7.280 -40.850 30.744 1.00150.66 N +ATOM 3777 N TYR B 253 -9.732 -36.681 35.180 1.00179.09 N +ATOM 3778 CA TYR B 253 -8.659 -36.137 36.021 1.00185.65 C +ATOM 3779 C TYR B 253 -9.224 -35.471 37.265 1.00184.62 C +ATOM 3780 O TYR B 253 -8.587 -35.480 38.325 1.00219.13 O +ATOM 3781 CB TYR B 253 -7.780 -35.160 35.232 1.00171.71 C +ATOM 3782 CG TYR B 253 -6.896 -35.885 34.239 1.00153.89 C +ATOM 3783 CD1 TYR B 253 -7.360 -36.159 32.960 1.00141.70 C +ATOM 3784 CD2 TYR B 253 -5.633 -36.365 34.596 1.00144.21 C +ATOM 3785 CE1 TYR B 253 -6.592 -36.847 32.036 1.00114.26 C +ATOM 3786 CE2 TYR B 253 -4.858 -37.052 33.673 1.00149.93 C +ATOM 3787 CZ TYR B 253 -5.353 -37.302 32.400 1.00133.14 C +ATOM 3788 OH TYR B 253 -4.593 -37.997 31.485 1.00130.28 O +ATOM 3789 N ARG B 254 -10.417 -34.895 37.130 1.00149.19 N +ATOM 3790 CA ARG B 254 -11.166 -34.410 38.284 1.00165.63 C +ATOM 3791 C ARG B 254 -11.414 -35.557 39.268 1.00183.64 C +ATOM 3792 O ARG B 254 -11.310 -35.374 40.492 1.00201.96 O +ATOM 3793 CB ARG B 254 -12.509 -33.808 37.852 1.00161.53 C +ATOM 3794 CG ARG B 254 -13.297 -33.175 38.993 1.00156.34 C +ATOM 3795 CD ARG B 254 -14.402 -32.236 38.515 1.00146.14 C +ATOM 3796 NE ARG B 254 -13.923 -31.032 37.830 1.00154.62 N +ATOM 3797 CZ ARG B 254 -14.023 -30.792 36.521 1.00141.97 C +ATOM 3798 NH1 ARG B 254 -14.572 -31.682 35.707 1.00112.19 N +ATOM 3799 NH2 ARG B 254 -13.563 -29.647 36.023 1.00140.99 N +ATOM 3800 N HIS B 255 -11.725 -36.736 38.724 1.00178.45 N +ATOM 3801 CA HIS B 255 -11.988 -37.930 39.537 1.00201.83 C +ATOM 3802 C HIS B 255 -10.739 -38.465 40.236 1.00182.98 C +ATOM 3803 O HIS B 255 -10.819 -38.956 41.364 1.00199.16 O +ATOM 3804 CB HIS B 255 -12.629 -39.041 38.694 1.00203.19 C +ATOM 3805 CG HIS B 255 -14.094 -39.234 38.952 1.00216.39 C +ATOM 3806 ND1 HIS B 255 -15.055 -38.362 38.483 1.00208.02 N +ATOM 3807 CD2 HIS B 255 -14.761 -40.198 39.631 1.00195.13 C +ATOM 3808 CE1 HIS B 255 -16.249 -38.780 38.866 1.00195.14 C +ATOM 3809 NE2 HIS B 255 -16.098 -39.891 39.566 1.00191.64 N +ATOM 3810 N MET B 256 -9.586 -38.340 39.591 1.00165.29 N +ATOM 3811 CA MET B 256 -8.338 -38.782 40.213 1.00154.65 C +ATOM 3812 C MET B 256 -7.945 -37.905 41.421 1.00124.99 C +ATOM 3813 O MET B 256 -7.268 -38.382 42.343 1.00139.02 O +ATOM 3814 CB MET B 256 -7.207 -38.836 39.178 1.00177.03 C +ATOM 3815 CG MET B 256 -7.548 -39.652 37.934 1.00182.88 C +ATOM 3816 SD MET B 256 -6.142 -40.198 36.948 1.00188.79 S +ATOM 3817 CE MET B 256 -5.399 -41.398 38.062 1.00142.77 C +ATOM 3818 N SER B 257 -8.434 -36.665 41.451 1.00111.31 N +ATOM 3819 CA SER B 257 -8.297 -35.779 42.613 1.00122.37 C +ATOM 3820 C SER B 257 -9.270 -36.134 43.739 1.00119.36 C +ATOM 3821 O SER B 257 -8.932 -36.953 44.603 1.00151.40 O +ATOM 3822 CB SER B 257 -8.530 -34.327 42.199 1.00138.66 C +ATOM 3823 OG SER B 257 -7.919 -34.050 40.941 1.00142.23 O +TER 3824 SER B 257 +ATOM 3825 N LEU C 2 8.901 -55.089 15.897 1.00101.35 N +ATOM 3826 CA LEU C 2 9.392 -55.131 17.318 1.00116.74 C +ATOM 3827 C LEU C 2 10.903 -54.809 17.390 1.00127.42 C +ATOM 3828 O LEU C 2 11.767 -55.684 17.645 1.00 87.80 O +ATOM 3829 CB LEU C 2 9.082 -56.484 17.970 1.00138.26 C +ATOM 3830 CG LEU C 2 7.604 -56.926 18.109 1.00130.68 C +ATOM 3831 CD1 LEU C 2 7.549 -58.309 18.756 1.00140.19 C +ATOM 3832 CD2 LEU C 2 6.717 -55.948 18.879 1.00120.69 C +ATOM 3833 N THR C 3 11.199 -53.576 16.970 1.00143.96 N +ATOM 3834 CA THR C 3 12.464 -52.889 17.239 1.00131.79 C +ATOM 3835 C THR C 3 12.205 -51.402 17.563 1.00142.44 C +ATOM 3836 O THR C 3 13.124 -50.664 17.931 1.00179.06 O +ATOM 3837 CB THR C 3 13.448 -52.939 16.051 1.00115.73 C +ATOM 3838 OG1 THR C 3 12.960 -52.129 14.974 1.00 70.94 O +ATOM 3839 CG2 THR C 3 13.686 -54.383 15.603 1.00121.53 C +ATOM 3840 N ALA C 4 10.963 -50.952 17.400 1.00129.26 N +ATOM 3841 CA ALA C 4 10.517 -49.680 17.978 1.00139.78 C +ATOM 3842 C ALA C 4 10.243 -49.886 19.489 1.00133.64 C +ATOM 3843 O ALA C 4 10.535 -50.952 20.026 1.00123.64 O +ATOM 3844 CB ALA C 4 9.285 -49.163 17.237 1.00122.67 C +ATOM 3845 N PRO C 5 9.765 -48.853 20.206 1.00140.98 N +ATOM 3846 CA PRO C 5 9.884 -49.047 21.646 1.00125.71 C +ATOM 3847 C PRO C 5 8.748 -49.915 22.217 1.00133.21 C +ATOM 3848 O PRO C 5 7.806 -50.241 21.503 1.00153.61 O +ATOM 3849 CB PRO C 5 9.813 -47.623 22.192 1.00129.26 C +ATOM 3850 CG PRO C 5 9.016 -46.855 21.180 1.00161.02 C +ATOM 3851 CD PRO C 5 9.074 -47.593 19.866 1.00156.60 C +ATOM 3852 N PRO C 6 8.881 -50.355 23.474 1.00129.34 N +ATOM 3853 CA PRO C 6 7.771 -50.969 24.198 1.00113.57 C +ATOM 3854 C PRO C 6 6.803 -49.930 24.711 1.00102.93 C +ATOM 3855 O PRO C 6 7.202 -48.786 24.994 1.00113.41 O +ATOM 3856 CB PRO C 6 8.450 -51.698 25.361 1.00137.18 C +ATOM 3857 CG PRO C 6 9.834 -51.149 25.464 1.00118.78 C +ATOM 3858 CD PRO C 6 10.170 -50.442 24.189 1.00131.65 C +ATOM 3859 N LYS C 7 5.544 -50.315 24.861 1.00 86.82 N +ATOM 3860 CA LYS C 7 4.540 -49.347 25.294 1.00108.17 C +ATOM 3861 C LYS C 7 4.300 -49.349 26.811 1.00100.32 C +ATOM 3862 O LYS C 7 4.766 -50.247 27.529 1.00 53.74 O +ATOM 3863 CB LYS C 7 3.225 -49.554 24.547 1.00123.23 C +ATOM 3864 CG LYS C 7 3.284 -49.240 23.066 1.00126.60 C +ATOM 3865 CD LYS C 7 3.315 -50.491 22.191 1.00116.90 C +ATOM 3866 CE LYS C 7 3.056 -50.137 20.739 1.00112.50 C +ATOM 3867 NZ LYS C 7 3.725 -51.072 19.799 1.00106.69 N +ATOM 3868 N GLU C 8 3.569 -48.320 27.268 1.00107.25 N +ATOM 3869 CA GLU C 8 3.452 -47.989 28.689 1.00104.17 C +ATOM 3870 C GLU C 8 2.752 -49.086 29.471 1.00 88.16 C +ATOM 3871 O GLU C 8 1.591 -49.388 29.240 1.00 82.76 O +ATOM 3872 CB GLU C 8 2.749 -46.603 28.925 1.00117.40 C +ATOM 3873 CG GLU C 8 1.231 -46.533 28.867 1.00141.34 C +ATOM 3874 CD GLU C 8 0.661 -45.184 29.333 1.00142.29 C +ATOM 3875 OE1 GLU C 8 0.959 -44.740 30.457 1.00144.23 O +ATOM 3876 OE2 GLU C 8 -0.133 -44.577 28.600 1.00126.63 O +ATOM 3877 N ALA C 9 3.475 -49.666 30.414 1.00 81.99 N +ATOM 3878 CA ALA C 9 2.896 -50.562 31.393 1.00 78.93 C +ATOM 3879 C ALA C 9 2.525 -49.786 32.668 1.00 94.14 C +ATOM 3880 O ALA C 9 3.405 -49.268 33.363 1.00102.91 O +ATOM 3881 CB ALA C 9 3.896 -51.649 31.704 1.00 79.23 C +ATOM 3882 N ALA C 10 1.224 -49.731 32.967 1.00 85.48 N +ATOM 3883 CA ALA C 10 0.652 -48.901 34.043 1.00 89.63 C +ATOM 3884 C ALA C 10 0.410 -47.477 33.560 1.00 91.52 C +ATOM 3885 O ALA C 10 1.008 -47.029 32.600 1.00 72.15 O +ATOM 3886 CB ALA C 10 1.510 -48.909 35.319 1.00 76.75 C +ATOM 3887 N ARG C 11 -0.477 -46.773 34.253 1.00115.36 N +ATOM 3888 CA ARG C 11 -0.848 -45.400 33.894 1.00135.13 C +ATOM 3889 C ARG C 11 -0.149 -44.415 34.828 1.00122.80 C +ATOM 3890 O ARG C 11 0.123 -44.750 35.970 1.00123.47 O +ATOM 3891 CB ARG C 11 -2.373 -45.204 34.017 1.00166.65 C +ATOM 3892 CG ARG C 11 -2.922 -45.308 35.436 1.00170.67 C +ATOM 3893 CD ARG C 11 -4.381 -45.767 35.439 1.00178.87 C +ATOM 3894 NE ARG C 11 -4.533 -47.131 35.948 1.00187.76 N +ATOM 3895 CZ ARG C 11 -5.704 -47.748 36.095 1.00160.49 C +ATOM 3896 NH1 ARG C 11 -6.829 -47.105 35.818 1.00170.21 N +ATOM 3897 NH2 ARG C 11 -5.753 -48.998 36.535 1.00133.49 N +ATOM 3898 N PRO C 12 0.103 -43.177 34.359 1.00 97.94 N +ATOM 3899 CA PRO C 12 0.461 -42.142 35.305 1.00 77.81 C +ATOM 3900 C PRO C 12 -0.701 -41.842 36.245 1.00 78.70 C +ATOM 3901 O PRO C 12 -1.751 -41.377 35.819 1.00 75.78 O +ATOM 3902 CB PRO C 12 0.771 -40.926 34.412 1.00 82.69 C +ATOM 3903 CG PRO C 12 0.879 -41.438 33.028 1.00 89.28 C +ATOM 3904 CD PRO C 12 -0.002 -42.650 32.989 1.00106.46 C +ATOM 3905 N THR C 13 -0.520 -42.155 37.518 1.00 88.96 N +ATOM 3906 CA THR C 13 -1.413 -41.683 38.568 1.00103.40 C +ATOM 3907 C THR C 13 -0.852 -40.417 39.221 1.00 95.28 C +ATOM 3908 O THR C 13 0.355 -40.171 39.141 1.00125.14 O +ATOM 3909 CB THR C 13 -1.562 -42.778 39.634 1.00132.38 C +ATOM 3910 OG1 THR C 13 -2.606 -42.419 40.543 1.00209.92 O +ATOM 3911 CG2 THR C 13 -0.221 -43.045 40.410 1.00114.34 C +ATOM 3912 N LEU C 14 -1.672 -39.646 39.923 1.00 79.16 N +ATOM 3913 CA LEU C 14 -1.075 -38.637 40.807 1.00 81.77 C +ATOM 3914 C LEU C 14 -0.454 -39.311 42.045 1.00 80.80 C +ATOM 3915 O LEU C 14 -0.747 -40.450 42.327 1.00 71.03 O +ATOM 3916 CB LEU C 14 -2.040 -37.508 41.164 1.00 80.09 C +ATOM 3917 CG LEU C 14 -3.375 -37.868 41.766 1.00 95.32 C +ATOM 3918 CD1 LEU C 14 -3.834 -36.794 42.740 1.00 97.31 C +ATOM 3919 CD2 LEU C 14 -4.376 -38.017 40.646 1.00116.48 C +ATOM 3920 N MET C 15 0.484 -38.658 42.723 1.00105.46 N +ATOM 3921 CA MET C 15 1.480 -39.395 43.529 1.00112.41 C +ATOM 3922 C MET C 15 0.825 -40.026 44.768 1.00 90.68 C +ATOM 3923 O MET C 15 0.220 -39.320 45.572 1.00 93.94 O +ATOM 3924 CB MET C 15 2.671 -38.486 43.942 1.00138.85 C +ATOM 3925 CG MET C 15 3.986 -39.245 44.130 1.00144.80 C +ATOM 3926 SD MET C 15 5.200 -38.712 45.367 1.00158.02 S +ATOM 3927 CE MET C 15 4.262 -37.780 46.584 1.00121.52 C +ATOM 3928 N PRO C 16 0.995 -41.342 44.946 1.00 66.60 N +ATOM 3929 CA PRO C 16 0.298 -42.145 45.939 1.00 67.08 C +ATOM 3930 C PRO C 16 0.688 -41.800 47.373 1.00 80.96 C +ATOM 3931 O PRO C 16 1.483 -42.493 48.002 1.00 98.33 O +ATOM 3932 CB PRO C 16 0.703 -43.577 45.590 1.00 71.23 C +ATOM 3933 CG PRO C 16 1.990 -43.422 44.859 1.00 87.69 C +ATOM 3934 CD PRO C 16 1.846 -42.162 44.077 1.00 79.67 C +ATOM 3935 N ARG C 17 0.067 -40.761 47.908 1.00107.31 N +ATOM 3936 CA ARG C 17 0.195 -40.428 49.324 1.00126.88 C +ATOM 3937 C ARG C 17 -0.860 -41.186 50.128 1.00146.64 C +ATOM 3938 O ARG C 17 -1.958 -41.423 49.630 1.00171.72 O +ATOM 3939 CB ARG C 17 0.018 -38.924 49.507 1.00148.84 C +ATOM 3940 CG ARG C 17 1.305 -38.148 49.331 1.00159.03 C +ATOM 3941 CD ARG C 17 1.066 -36.663 49.088 1.00150.97 C +ATOM 3942 NE ARG C 17 0.614 -36.395 47.723 1.00121.02 N +ATOM 3943 CZ ARG C 17 0.245 -35.193 47.287 1.00118.25 C +ATOM 3944 NH1 ARG C 17 0.219 -34.162 48.132 1.00109.65 N +ATOM 3945 NH2 ARG C 17 -0.080 -35.018 46.006 1.00107.89 N +ATOM 3946 N ALA C 18 -0.541 -41.569 51.362 1.00152.51 N +ATOM 3947 CA ALA C 18 -1.469 -42.370 52.175 1.00144.68 C +ATOM 3948 C ALA C 18 -2.007 -41.615 53.404 1.00148.19 C +ATOM 3949 O ALA C 18 -2.706 -40.601 53.256 1.00176.23 O +ATOM 3950 CB ALA C 18 -0.832 -43.693 52.580 1.00137.47 C +ATOM 3951 N GLN C 19 -1.730 -42.125 54.603 1.00119.33 N +ATOM 3952 CA GLN C 19 -2.530 -41.768 55.777 1.00147.86 C +ATOM 3953 C GLN C 19 -2.262 -40.334 56.221 1.00137.85 C +ATOM 3954 O GLN C 19 -3.189 -39.545 56.473 1.00 98.61 O +ATOM 3955 CB GLN C 19 -2.235 -42.736 56.930 1.00177.38 C +ATOM 3956 CG GLN C 19 -3.112 -42.538 58.165 1.00185.30 C +ATOM 3957 CD GLN C 19 -4.602 -42.584 57.854 1.00151.62 C +ATOM 3958 OE1 GLN C 19 -5.132 -43.622 57.458 1.00126.95 O +ATOM 3959 NE2 GLN C 19 -5.276 -41.451 58.008 1.00133.89 N +ATOM 3960 N SER C 20 -0.975 -40.032 56.361 1.00135.83 N +ATOM 3961 CA SER C 20 -0.510 -38.688 56.651 1.00138.15 C +ATOM 3962 C SER C 20 -1.274 -37.649 55.818 1.00147.48 C +ATOM 3963 O SER C 20 -1.787 -36.666 56.355 1.00123.38 O +ATOM 3964 CB SER C 20 0.994 -38.610 56.362 1.00133.25 C +ATOM 3965 OG SER C 20 1.691 -39.666 57.007 1.00136.13 O +ATOM 3966 N TYR C 21 -1.342 -37.884 54.507 1.00165.47 N +ATOM 3967 CA TYR C 21 -2.076 -37.019 53.581 1.00163.51 C +ATOM 3968 C TYR C 21 -3.545 -36.847 53.973 1.00162.02 C +ATOM 3969 O TYR C 21 -4.062 -35.718 54.031 1.00162.26 O +ATOM 3970 CB TYR C 21 -1.997 -37.578 52.157 1.00147.73 C +ATOM 3971 CG TYR C 21 -2.694 -36.714 51.127 1.00147.50 C +ATOM 3972 CD1 TYR C 21 -2.113 -35.530 50.680 1.00141.53 C +ATOM 3973 CD2 TYR C 21 -3.947 -37.063 50.624 1.00143.17 C +ATOM 3974 CE1 TYR C 21 -2.748 -34.730 49.754 1.00140.58 C +ATOM 3975 CE2 TYR C 21 -4.592 -36.268 49.689 1.00136.28 C +ATOM 3976 CZ TYR C 21 -3.988 -35.105 49.259 1.00143.55 C +ATOM 3977 OH TYR C 21 -4.595 -34.294 48.331 1.00147.78 O +ATOM 3978 N LYS C 22 -4.218 -37.966 54.224 1.00142.94 N +ATOM 3979 CA LYS C 22 -5.635 -37.946 54.554 1.00141.97 C +ATOM 3980 C LYS C 22 -5.911 -37.127 55.811 1.00131.23 C +ATOM 3981 O LYS C 22 -6.914 -36.407 55.893 1.00124.94 O +ATOM 3982 CB LYS C 22 -6.151 -39.374 54.730 1.00148.93 C +ATOM 3983 CG LYS C 22 -6.637 -40.008 53.441 1.00151.77 C +ATOM 3984 CD LYS C 22 -8.073 -39.559 53.138 1.00170.73 C +ATOM 3985 CE LYS C 22 -9.065 -40.671 53.510 1.00188.90 C +ATOM 3986 NZ LYS C 22 -8.881 -41.877 52.659 1.00197.67 N +ATOM 3987 N ASP C 23 -5.046 -37.286 56.807 1.00133.90 N +ATOM 3988 CA ASP C 23 -5.130 -36.490 58.031 1.00149.48 C +ATOM 3989 C ASP C 23 -4.903 -35.016 57.718 1.00134.67 C +ATOM 3990 O ASP C 23 -5.618 -34.144 58.223 1.00137.93 O +ATOM 3991 CB ASP C 23 -4.089 -36.969 59.053 1.00151.28 C +ATOM 3992 CG ASP C 23 -4.392 -38.341 59.582 1.00162.38 C +ATOM 3993 OD1 ASP C 23 -5.579 -38.607 59.860 1.00193.92 O +ATOM 3994 OD2 ASP C 23 -3.447 -39.145 59.740 1.00180.56 O +ATOM 3995 N LEU C 24 -3.883 -34.755 56.907 1.00124.59 N +ATOM 3996 CA LEU C 24 -3.425 -33.396 56.629 1.00149.87 C +ATOM 3997 C LEU C 24 -4.487 -32.587 55.880 1.00159.58 C +ATOM 3998 O LEU C 24 -4.628 -31.367 56.096 1.00147.30 O +ATOM 3999 CB LEU C 24 -2.126 -33.448 55.811 1.00148.48 C +ATOM 4000 CG LEU C 24 -1.473 -32.117 55.402 1.00137.39 C +ATOM 4001 CD1 LEU C 24 -0.558 -31.589 56.500 1.00120.91 C +ATOM 4002 CD2 LEU C 24 -0.704 -32.295 54.102 1.00134.06 C +ATOM 4003 N THR C 25 -5.224 -33.266 55.001 1.00172.90 N +ATOM 4004 CA THR C 25 -6.242 -32.609 54.173 1.00187.16 C +ATOM 4005 C THR C 25 -7.509 -32.287 54.962 1.00202.63 C +ATOM 4006 O THR C 25 -8.017 -31.159 54.906 1.00196.02 O +ATOM 4007 CB THR C 25 -6.623 -33.474 52.956 1.00170.79 C +ATOM 4008 OG1 THR C 25 -6.831 -34.828 53.369 1.00153.21 O +ATOM 4009 CG2 THR C 25 -5.515 -33.434 51.922 1.00186.29 C +ATOM 4010 N HIS C 26 -7.980 -33.267 55.732 1.00210.52 N +ATOM 4011 CA HIS C 26 -9.205 -33.128 56.522 1.00185.74 C +ATOM 4012 C HIS C 26 -8.943 -32.452 57.882 1.00157.98 C +ATOM 4013 O HIS C 26 -9.559 -32.785 58.889 1.00118.82 O +ATOM 4014 CB HIS C 26 -9.865 -34.505 56.702 1.00187.51 C +ATOM 4015 CG HIS C 26 -10.311 -35.128 55.409 1.00193.36 C +ATOM 4016 ND1 HIS C 26 -9.425 -35.583 54.454 1.00179.19 N +ATOM 4017 CD2 HIS C 26 -11.550 -35.334 54.899 1.00199.98 C +ATOM 4018 CE1 HIS C 26 -10.098 -36.072 53.427 1.00186.44 C +ATOM 4019 NE2 HIS C 26 -11.389 -35.924 53.667 1.00195.26 N +ATOM 4020 N LEU C 27 -8.033 -31.486 57.905 1.00148.95 N +ATOM 4021 CA LEU C 27 -7.802 -30.693 59.103 1.00135.79 C +ATOM 4022 C LEU C 27 -8.760 -29.503 59.124 1.00124.99 C +ATOM 4023 O LEU C 27 -8.911 -28.812 58.122 1.00110.62 O +ATOM 4024 CB LEU C 27 -6.345 -30.207 59.160 1.00138.06 C +ATOM 4025 CG LEU C 27 -5.355 -31.178 59.815 1.00156.61 C +ATOM 4026 CD1 LEU C 27 -3.921 -30.761 59.540 1.00170.03 C +ATOM 4027 CD2 LEU C 27 -5.594 -31.278 61.315 1.00165.19 C +ATOM 4028 N PRO C 28 -9.379 -29.236 60.284 1.00130.10 N +ATOM 4029 CA PRO C 28 -10.277 -28.083 60.438 1.00123.18 C +ATOM 4030 C PRO C 28 -9.596 -26.763 60.120 1.00113.55 C +ATOM 4031 O PRO C 28 -8.531 -26.485 60.654 1.00153.61 O +ATOM 4032 CB PRO C 28 -10.656 -28.128 61.924 1.00150.44 C +ATOM 4033 CG PRO C 28 -9.532 -28.866 62.591 1.00153.56 C +ATOM 4034 CD PRO C 28 -9.072 -29.877 61.579 1.00148.07 C +ATOM 4035 N ALA C 29 -10.212 -25.951 59.274 1.00112.12 N +ATOM 4036 CA ALA C 29 -9.533 -24.780 58.706 1.00111.01 C +ATOM 4037 C ALA C 29 -9.363 -23.643 59.737 1.00107.83 C +ATOM 4038 O ALA C 29 -10.184 -23.484 60.646 1.00130.39 O +ATOM 4039 CB ALA C 29 -10.273 -24.291 57.457 1.00 98.16 C +ATOM 4040 N PRO C 30 -8.261 -22.881 59.635 1.00 94.54 N +ATOM 4041 CA PRO C 30 -8.012 -21.696 60.463 1.00 89.54 C +ATOM 4042 C PRO C 30 -8.852 -20.487 60.031 1.00 86.32 C +ATOM 4043 O PRO C 30 -9.565 -20.558 59.021 1.00 58.03 O +ATOM 4044 CB PRO C 30 -6.554 -21.392 60.198 1.00 93.83 C +ATOM 4045 CG PRO C 30 -6.333 -21.855 58.799 1.00116.46 C +ATOM 4046 CD PRO C 30 -7.242 -23.037 58.588 1.00111.61 C +ATOM 4047 N THR C 31 -8.767 -19.396 60.795 1.00 90.19 N +ATOM 4048 CA THR C 31 -9.564 -18.194 60.507 1.00114.11 C +ATOM 4049 C THR C 31 -9.141 -17.517 59.201 1.00119.17 C +ATOM 4050 O THR C 31 -9.933 -16.827 58.561 1.00 91.69 O +ATOM 4051 CB THR C 31 -9.521 -17.154 61.661 1.00134.91 C +ATOM 4052 OG1 THR C 31 -8.168 -16.851 62.024 1.00129.43 O +ATOM 4053 CG2 THR C 31 -10.266 -17.667 62.887 1.00149.22 C +ATOM 4054 N GLY C 32 -7.874 -17.681 58.840 1.00140.38 N +ATOM 4055 CA GLY C 32 -7.389 -17.304 57.514 1.00152.61 C +ATOM 4056 C GLY C 32 -6.152 -18.125 57.211 1.00137.51 C +ATOM 4057 O GLY C 32 -5.483 -18.582 58.136 1.00131.29 O +ATOM 4058 N LYS C 33 -5.851 -18.344 55.932 1.00114.66 N +ATOM 4059 CA LYS C 33 -4.623 -19.044 55.590 1.00115.00 C +ATOM 4060 C LYS C 33 -3.386 -18.198 55.953 1.00116.95 C +ATOM 4061 O LYS C 33 -3.458 -16.966 55.964 1.00118.91 O +ATOM 4062 CB LYS C 33 -4.596 -19.423 54.119 1.00117.13 C +ATOM 4063 CG LYS C 33 -5.202 -20.778 53.826 1.00105.32 C +ATOM 4064 CD LYS C 33 -5.299 -21.004 52.328 1.00118.63 C +ATOM 4065 CE LYS C 33 -6.409 -21.987 52.008 1.00120.80 C +ATOM 4066 NZ LYS C 33 -6.635 -22.100 50.547 1.00158.34 N +ATOM 4067 N ILE C 34 -2.279 -18.859 56.283 1.00103.77 N +ATOM 4068 CA ILE C 34 -1.084 -18.165 56.716 1.00113.46 C +ATOM 4069 C ILE C 34 -0.065 -18.213 55.566 1.00139.94 C +ATOM 4070 O ILE C 34 -0.020 -19.176 54.791 1.00153.36 O +ATOM 4071 CB ILE C 34 -0.552 -18.751 58.053 1.00128.91 C +ATOM 4072 CG1 ILE C 34 -1.540 -18.470 59.182 1.00147.72 C +ATOM 4073 CG2 ILE C 34 0.785 -18.143 58.459 1.00148.00 C +ATOM 4074 CD1 ILE C 34 -2.110 -19.722 59.810 1.00171.96 C +ATOM 4075 N PHE C 35 0.663 -17.109 55.397 1.00142.95 N +ATOM 4076 CA PHE C 35 1.673 -16.963 54.354 1.00110.45 C +ATOM 4077 C PHE C 35 2.975 -17.591 54.814 1.00111.60 C +ATOM 4078 O PHE C 35 3.529 -17.173 55.829 1.00129.12 O +ATOM 4079 CB PHE C 35 1.929 -15.477 54.100 1.00104.89 C +ATOM 4080 CG PHE C 35 0.987 -14.850 53.127 1.00 91.04 C +ATOM 4081 CD1 PHE C 35 0.636 -15.504 51.947 1.00 75.54 C +ATOM 4082 CD2 PHE C 35 0.527 -13.561 53.349 1.00 85.26 C +ATOM 4083 CE1 PHE C 35 -0.214 -14.901 51.042 1.00 91.65 C +ATOM 4084 CE2 PHE C 35 -0.324 -12.956 52.443 1.00100.40 C +ATOM 4085 CZ PHE C 35 -0.702 -13.627 51.290 1.00 94.72 C +ATOM 4086 N VAL C 36 3.519 -18.512 54.021 1.00110.22 N +ATOM 4087 CA VAL C 36 4.733 -19.206 54.427 1.00 89.31 C +ATOM 4088 C VAL C 36 5.800 -19.251 53.342 1.00100.93 C +ATOM 4089 O VAL C 36 5.507 -19.218 52.152 1.00137.25 O +ATOM 4090 CB VAL C 36 4.400 -20.626 54.842 1.00 85.34 C +ATOM 4091 CG1 VAL C 36 4.121 -21.505 53.625 1.00 87.34 C +ATOM 4092 CG2 VAL C 36 5.528 -21.185 55.668 1.00 91.41 C +ATOM 4093 N SER C 37 7.050 -19.294 53.766 1.00 95.81 N +ATOM 4094 CA SER C 37 8.168 -19.346 52.837 1.00 99.61 C +ATOM 4095 C SER C 37 8.972 -20.604 53.130 1.00 90.40 C +ATOM 4096 O SER C 37 9.343 -20.850 54.257 1.00 55.58 O +ATOM 4097 CB SER C 37 9.074 -18.129 53.026 1.00 86.44 C +ATOM 4098 OG SER C 37 8.508 -16.959 52.501 1.00 56.36 O +ATOM 4099 N VAL C 38 9.316 -21.355 52.096 1.00101.76 N +ATOM 4100 CA VAL C 38 10.336 -22.392 52.246 1.00 99.51 C +ATOM 4101 C VAL C 38 11.485 -22.151 51.269 1.00 93.02 C +ATOM 4102 O VAL C 38 11.265 -22.150 50.054 1.00116.35 O +ATOM 4103 CB VAL C 38 9.776 -23.796 51.961 1.00 92.53 C +ATOM 4104 CG1 VAL C 38 10.881 -24.828 52.089 1.00 87.32 C +ATOM 4105 CG2 VAL C 38 8.622 -24.126 52.894 1.00 89.61 C +ATOM 4106 N TYR C 39 12.686 -21.965 51.808 1.00 67.45 N +ATOM 4107 CA TYR C 39 13.854 -21.679 51.011 1.00 69.91 C +ATOM 4108 C TYR C 39 14.534 -22.997 50.647 1.00 88.70 C +ATOM 4109 O TYR C 39 14.806 -23.265 49.474 1.00129.86 O +ATOM 4110 CB TYR C 39 14.803 -20.715 51.757 1.00 72.22 C +ATOM 4111 CG TYR C 39 14.440 -19.250 51.550 1.00 73.03 C +ATOM 4112 CD1 TYR C 39 13.373 -18.665 52.214 1.00 56.32 C +ATOM 4113 CD2 TYR C 39 15.171 -18.455 50.669 1.00100.41 C +ATOM 4114 CE1 TYR C 39 13.067 -17.338 52.033 1.00 61.37 C +ATOM 4115 CE2 TYR C 39 14.859 -17.117 50.464 1.00109.26 C +ATOM 4116 CZ TYR C 39 13.788 -16.564 51.132 1.00 84.34 C +ATOM 4117 OH TYR C 39 13.472 -15.219 50.888 1.00 86.61 O +ATOM 4118 N ASN C 40 14.842 -23.821 51.643 1.00102.53 N +ATOM 4119 CA ASN C 40 15.542 -25.087 51.386 1.00 97.63 C +ATOM 4120 C ASN C 40 15.571 -26.066 52.557 1.00 87.86 C +ATOM 4121 O ASN C 40 15.839 -25.682 53.698 1.00 90.65 O +ATOM 4122 CB ASN C 40 16.982 -24.821 50.991 1.00 98.87 C +ATOM 4123 CG ASN C 40 17.604 -26.004 50.292 1.00120.45 C +ATOM 4124 OD1 ASN C 40 18.563 -26.590 50.782 1.00143.92 O +ATOM 4125 ND2 ASN C 40 17.061 -26.355 49.126 1.00128.63 N +ATOM 4126 N ILE C 41 15.240 -27.323 52.280 1.00 92.04 N +ATOM 4127 CA ILE C 41 15.401 -28.391 53.259 1.00 97.54 C +ATOM 4128 C ILE C 41 16.431 -29.378 52.713 1.00120.18 C +ATOM 4129 O ILE C 41 16.188 -30.024 51.687 1.00119.16 O +ATOM 4130 CB ILE C 41 14.070 -29.120 53.570 1.00 79.06 C +ATOM 4131 CG1 ILE C 41 13.229 -28.341 54.579 1.00 90.05 C +ATOM 4132 CG2 ILE C 41 14.348 -30.465 54.215 1.00 80.00 C +ATOM 4133 CD1 ILE C 41 12.612 -27.063 54.054 1.00105.20 C +ATOM 4134 N GLN C 42 17.561 -29.513 53.410 1.00113.01 N +ATOM 4135 CA GLN C 42 18.696 -30.268 52.875 1.00110.04 C +ATOM 4136 C GLN C 42 18.644 -31.762 53.198 1.00 71.74 C +ATOM 4137 O GLN C 42 18.071 -32.146 54.196 1.00 51.31 O +ATOM 4138 CB GLN C 42 20.019 -29.658 53.366 1.00133.40 C +ATOM 4139 CG GLN C 42 20.281 -28.281 52.698 1.00151.73 C +ATOM 4140 CD GLN C 42 20.845 -28.405 51.291 1.00181.31 C +ATOM 4141 OE1 GLN C 42 21.284 -29.472 50.775 1.00210.47 O +ATOM 4142 NE2 GLN C 42 20.753 -27.291 50.630 1.00202.56 N +ATOM 4143 N ASP C 43 19.297 -32.562 52.357 1.00 53.32 N +ATOM 4144 CA ASP C 43 19.626 -33.919 52.670 1.00 50.59 C +ATOM 4145 C ASP C 43 20.805 -33.982 53.623 1.00 58.73 C +ATOM 4146 O ASP C 43 21.866 -34.538 53.285 1.00 57.63 O +ATOM 4147 CB ASP C 43 19.974 -34.681 51.408 1.00 58.51 C +ATOM 4148 CG ASP C 43 20.072 -36.205 51.643 1.00 83.46 C +ATOM 4149 OD1 ASP C 43 19.118 -36.779 52.217 1.00116.64 O +ATOM 4150 OD2 ASP C 43 21.030 -36.860 51.163 1.00 97.71 O +ATOM 4151 N GLU C 44 20.612 -33.480 54.853 1.00 78.37 N +ATOM 4152 CA GLU C 44 21.659 -33.506 55.903 1.00109.79 C +ATOM 4153 C GLU C 44 21.992 -34.953 56.446 1.00 94.46 C +ATOM 4154 O GLU C 44 22.733 -35.102 57.450 1.00 45.48 O +ATOM 4155 CB GLU C 44 21.285 -32.575 57.085 1.00121.19 C +ATOM 4156 CG GLU C 44 21.672 -31.094 56.920 1.00123.26 C +ATOM 4157 CD GLU C 44 21.272 -30.176 58.104 1.00118.30 C +ATOM 4158 OE1 GLU C 44 21.407 -30.554 59.290 1.00142.75 O +ATOM 4159 OE2 GLU C 44 20.725 -29.091 57.860 1.00 86.06 O +ATOM 4160 N THR C 45 21.571 -35.973 55.682 1.00 85.91 N +ATOM 4161 CA THR C 45 21.667 -37.364 56.103 1.00 85.27 C +ATOM 4162 C THR C 45 23.063 -37.961 56.017 1.00 89.43 C +ATOM 4163 O THR C 45 23.500 -38.646 56.928 1.00 83.37 O +ATOM 4164 CB THR C 45 20.658 -38.265 55.360 1.00 71.73 C +ATOM 4165 OG1 THR C 45 20.567 -39.507 56.058 1.00148.28 O +ATOM 4166 CG2 THR C 45 21.040 -38.531 53.928 1.00 51.79 C +ATOM 4167 N GLY C 46 23.787 -37.645 54.952 1.00123.18 N +ATOM 4168 CA GLY C 46 25.214 -38.002 54.857 1.00114.20 C +ATOM 4169 C GLY C 46 25.388 -39.393 54.270 1.00115.78 C +ATOM 4170 O GLY C 46 26.457 -40.030 54.355 1.00135.50 O +ATOM 4171 N GLN C 47 24.380 -39.845 53.560 1.00 84.03 N +ATOM 4172 CA GLN C 47 24.357 -41.209 53.280 1.00 66.13 C +ATOM 4173 C GLN C 47 24.124 -41.468 51.808 1.00 68.53 C +ATOM 4174 O GLN C 47 23.288 -40.842 51.130 1.00 82.85 O +ATOM 4175 CB GLN C 47 23.317 -41.822 54.152 1.00 64.18 C +ATOM 4176 CG GLN C 47 23.704 -41.807 55.602 1.00 72.01 C +ATOM 4177 CD GLN C 47 25.093 -42.369 55.826 1.00114.53 C +ATOM 4178 OE1 GLN C 47 25.321 -43.574 55.749 1.00130.59 O +ATOM 4179 NE2 GLN C 47 26.023 -41.503 56.171 1.00171.77 N +ATOM 4180 N PHE C 48 24.847 -42.466 51.327 1.00 70.01 N +ATOM 4181 CA PHE C 48 24.706 -42.959 49.969 1.00 75.01 C +ATOM 4182 C PHE C 48 24.365 -44.459 49.963 1.00 84.64 C +ATOM 4183 O PHE C 48 24.561 -45.185 50.946 1.00100.79 O +ATOM 4184 CB PHE C 48 26.005 -42.693 49.189 1.00 65.72 C +ATOM 4185 CG PHE C 48 26.268 -41.265 48.997 1.00 52.06 C +ATOM 4186 CD1 PHE C 48 26.640 -40.497 50.064 1.00 54.24 C +ATOM 4187 CD2 PHE C 48 26.022 -40.680 47.801 1.00 58.28 C +ATOM 4188 CE1 PHE C 48 26.788 -39.143 49.955 1.00 67.24 C +ATOM 4189 CE2 PHE C 48 26.152 -39.327 47.672 1.00 86.68 C +ATOM 4190 CZ PHE C 48 26.560 -38.556 48.748 1.00 92.09 C +ATOM 4191 N LYS C 49 23.978 -44.933 48.791 1.00 95.49 N +ATOM 4192 CA LYS C 49 23.657 -46.334 48.618 1.00 93.32 C +ATOM 4193 C LYS C 49 24.927 -47.177 48.564 1.00 83.39 C +ATOM 4194 O LYS C 49 25.962 -46.746 48.034 1.00 86.67 O +ATOM 4195 CB LYS C 49 22.795 -46.526 47.357 1.00114.06 C +ATOM 4196 CG LYS C 49 21.443 -45.833 47.488 1.00111.89 C +ATOM 4197 CD LYS C 49 20.425 -46.124 46.403 1.00133.44 C +ATOM 4198 CE LYS C 49 19.110 -45.476 46.842 1.00165.60 C +ATOM 4199 NZ LYS C 49 17.953 -45.683 45.927 1.00197.21 N +ATOM 4200 N PRO C 50 24.832 -48.402 49.079 1.00 82.79 N +ATOM 4201 CA PRO C 50 25.940 -49.334 49.046 1.00 97.47 C +ATOM 4202 C PRO C 50 26.120 -50.023 47.686 1.00 75.68 C +ATOM 4203 O PRO C 50 25.237 -49.974 46.835 1.00 63.11 O +ATOM 4204 CB PRO C 50 25.564 -50.358 50.131 1.00106.76 C +ATOM 4205 CG PRO C 50 24.081 -50.353 50.143 1.00 94.53 C +ATOM 4206 CD PRO C 50 23.672 -48.945 49.806 1.00 89.49 C +ATOM 4207 N TYR C 51 27.272 -50.666 47.517 1.00 75.76 N +ATOM 4208 CA TYR C 51 27.488 -51.527 46.386 1.00 71.60 C +ATOM 4209 C TYR C 51 26.296 -52.469 46.232 1.00 74.32 C +ATOM 4210 O TYR C 51 25.820 -53.040 47.216 1.00 66.31 O +ATOM 4211 CB TYR C 51 28.781 -52.336 46.546 1.00 73.26 C +ATOM 4212 CG TYR C 51 29.214 -52.948 45.249 1.00 75.23 C +ATOM 4213 CD1 TYR C 51 30.007 -52.237 44.383 1.00 91.68 C +ATOM 4214 CD2 TYR C 51 28.819 -54.233 44.871 1.00 86.84 C +ATOM 4215 CE1 TYR C 51 30.385 -52.749 43.151 1.00101.92 C +ATOM 4216 CE2 TYR C 51 29.240 -54.784 43.654 1.00100.06 C +ATOM 4217 CZ TYR C 51 29.989 -54.000 42.782 1.00102.63 C +ATOM 4218 OH TYR C 51 30.388 -54.440 41.546 1.00 95.68 O +ATOM 4219 N PRO C 52 25.813 -52.657 44.993 1.00 88.14 N +ATOM 4220 CA PRO C 52 26.340 -52.189 43.703 1.00110.50 C +ATOM 4221 C PRO C 52 25.807 -50.860 43.160 1.00128.52 C +ATOM 4222 O PRO C 52 25.970 -50.600 41.963 1.00 93.99 O +ATOM 4223 CB PRO C 52 25.909 -53.300 42.747 1.00114.43 C +ATOM 4224 CG PRO C 52 24.591 -53.738 43.299 1.00114.14 C +ATOM 4225 CD PRO C 52 24.693 -53.597 44.802 1.00 99.47 C +ATOM 4226 N ALA C 53 25.213 -50.020 44.011 1.00140.61 N +ATOM 4227 CA ALA C 53 24.785 -48.700 43.557 1.00128.27 C +ATOM 4228 C ALA C 53 25.989 -47.877 43.128 1.00130.93 C +ATOM 4229 O ALA C 53 27.148 -48.137 43.524 1.00 88.41 O +ATOM 4230 CB ALA C 53 24.016 -47.962 44.638 1.00136.50 C +ATOM 4231 N SER C 54 25.726 -46.855 42.325 1.00120.38 N +ATOM 4232 CA SER C 54 26.779 -45.897 42.074 1.00104.71 C +ATOM 4233 C SER C 54 27.239 -45.337 43.422 1.00 81.27 C +ATOM 4234 O SER C 54 26.415 -45.031 44.304 1.00 68.42 O +ATOM 4235 CB SER C 54 26.316 -44.793 41.111 1.00113.18 C +ATOM 4236 OG SER C 54 27.115 -43.609 41.215 1.00 87.88 O +ATOM 4237 N ASN C 55 28.546 -45.132 43.525 1.00 62.01 N +ATOM 4238 CA ASN C 55 29.126 -44.377 44.610 1.00 60.46 C +ATOM 4239 C ASN C 55 28.367 -43.071 44.970 1.00 74.56 C +ATOM 4240 O ASN C 55 28.279 -42.640 46.130 1.00 47.29 O +ATOM 4241 CB ASN C 55 30.548 -44.020 44.246 1.00 48.59 C +ATOM 4242 CG ASN C 55 31.356 -43.658 45.439 1.00 74.95 C +ATOM 4243 OD1 ASN C 55 31.007 -43.956 46.591 1.00150.18 O +ATOM 4244 ND2 ASN C 55 32.491 -43.074 45.185 1.00 91.34 N +ATOM 4245 N PHE C 56 27.758 -42.469 43.951 1.00102.89 N +ATOM 4246 CA PHE C 56 27.144 -41.142 44.060 1.00 95.79 C +ATOM 4247 C PHE C 56 25.629 -41.173 44.248 1.00 98.91 C +ATOM 4248 O PHE C 56 24.986 -40.124 44.296 1.00 93.77 O +ATOM 4249 CB PHE C 56 27.416 -40.344 42.797 1.00 88.19 C +ATOM 4250 CG PHE C 56 28.886 -40.196 42.490 1.00 76.16 C +ATOM 4251 CD1 PHE C 56 29.762 -39.580 43.366 1.00 46.33 C +ATOM 4252 CD2 PHE C 56 29.382 -40.713 41.325 1.00 98.83 C +ATOM 4253 CE1 PHE C 56 31.086 -39.434 43.053 1.00 39.32 C +ATOM 4254 CE2 PHE C 56 30.718 -40.530 40.992 1.00 82.49 C +ATOM 4255 CZ PHE C 56 31.572 -39.897 41.867 1.00 45.33 C +ATOM 4256 N SER C 57 25.042 -42.362 44.295 1.00 81.14 N +ATOM 4257 CA SER C 57 23.600 -42.457 44.491 1.00 64.10 C +ATOM 4258 C SER C 57 23.253 -42.171 45.944 1.00 58.19 C +ATOM 4259 O SER C 57 23.673 -42.901 46.865 1.00 57.90 O +ATOM 4260 CB SER C 57 23.086 -43.831 44.065 1.00 62.90 C +ATOM 4261 OG SER C 57 23.073 -43.919 42.651 1.00 64.79 O +ATOM 4262 N THR C 58 22.537 -41.079 46.172 1.00 51.37 N +ATOM 4263 CA THR C 58 22.189 -40.714 47.533 1.00 67.74 C +ATOM 4264 C THR C 58 21.168 -41.683 48.106 1.00 75.04 C +ATOM 4265 O THR C 58 20.336 -42.213 47.414 1.00 79.46 O +ATOM 4266 CB THR C 58 21.595 -39.305 47.598 1.00 54.68 C +ATOM 4267 OG1 THR C 58 20.398 -39.266 46.834 1.00 47.33 O +ATOM 4268 CG2 THR C 58 22.566 -38.343 47.036 1.00 45.14 C +ATOM 4269 N ALA C 59 21.161 -41.841 49.408 1.00 83.51 N +ATOM 4270 CA ALA C 59 20.220 -42.765 49.977 1.00 82.28 C +ATOM 4271 C ALA C 59 18.823 -42.175 50.026 1.00 79.12 C +ATOM 4272 O ALA C 59 17.834 -42.904 50.131 1.00124.31 O +ATOM 4273 CB ALA C 59 20.667 -43.171 51.360 1.00106.65 C +ATOM 4274 N VAL C 60 18.740 -40.851 49.973 1.00 83.70 N +ATOM 4275 CA VAL C 60 17.483 -40.140 50.160 1.00100.33 C +ATOM 4276 C VAL C 60 17.326 -39.131 49.031 1.00100.22 C +ATOM 4277 O VAL C 60 18.296 -38.472 48.642 1.00102.05 O +ATOM 4278 CB VAL C 60 17.499 -39.397 51.508 1.00101.64 C +ATOM 4279 CG1 VAL C 60 16.210 -38.604 51.733 1.00106.24 C +ATOM 4280 CG2 VAL C 60 17.731 -40.381 52.640 1.00100.59 C +ATOM 4281 N PRO C 61 16.105 -38.990 48.511 1.00 75.25 N +ATOM 4282 CA PRO C 61 15.928 -38.000 47.461 1.00 91.59 C +ATOM 4283 C PRO C 61 16.182 -36.570 47.918 1.00 97.65 C +ATOM 4284 O PRO C 61 15.837 -36.206 49.052 1.00 73.37 O +ATOM 4285 CB PRO C 61 14.465 -38.175 47.051 1.00 92.21 C +ATOM 4286 CG PRO C 61 13.820 -38.825 48.225 1.00 72.12 C +ATOM 4287 CD PRO C 61 14.869 -39.713 48.806 1.00 59.50 C +ATOM 4288 N GLN C 62 16.736 -35.764 47.008 1.00114.59 N +ATOM 4289 CA GLN C 62 17.125 -34.390 47.316 1.00114.02 C +ATOM 4290 C GLN C 62 15.955 -33.442 47.086 1.00117.42 C +ATOM 4291 O GLN C 62 16.163 -32.294 46.711 1.00156.28 O +ATOM 4292 CB GLN C 62 18.301 -33.946 46.433 1.00 94.25 C +ATOM 4293 CG GLN C 62 19.450 -34.923 46.392 1.00 79.59 C +ATOM 4294 CD GLN C 62 20.014 -35.177 47.764 1.00 85.61 C +ATOM 4295 OE1 GLN C 62 20.747 -34.348 48.316 1.00118.23 O +ATOM 4296 NE2 GLN C 62 19.662 -36.310 48.344 1.00 76.06 N +ATOM 4297 N SER C 63 14.743 -33.903 47.371 1.00 82.96 N +ATOM 4298 CA SER C 63 13.556 -33.228 46.909 1.00 74.28 C +ATOM 4299 C SER C 63 12.642 -32.769 48.051 1.00 75.55 C +ATOM 4300 O SER C 63 11.503 -32.341 47.838 1.00 80.23 O +ATOM 4301 CB SER C 63 12.820 -34.170 45.955 1.00 81.67 C +ATOM 4302 OG SER C 63 12.379 -35.366 46.582 1.00 97.22 O +ATOM 4303 N ALA C 64 13.140 -32.882 49.273 1.00 84.57 N +ATOM 4304 CA ALA C 64 12.344 -32.625 50.472 1.00 88.81 C +ATOM 4305 C ALA C 64 11.652 -31.241 50.463 1.00102.52 C +ATOM 4306 O ALA C 64 10.514 -31.086 50.923 1.00 70.13 O +ATOM 4307 CB ALA C 64 13.231 -32.773 51.696 1.00 91.48 C +ATOM 4308 N THR C 65 12.370 -30.243 49.959 1.00121.80 N +ATOM 4309 CA THR C 65 11.894 -28.870 49.928 1.00119.22 C +ATOM 4310 C THR C 65 10.541 -28.794 49.257 1.00122.72 C +ATOM 4311 O THR C 65 9.609 -28.165 49.774 1.00204.93 O +ATOM 4312 CB THR C 65 12.864 -28.006 49.124 1.00118.73 C +ATOM 4313 OG1 THR C 65 14.201 -28.403 49.447 1.00150.41 O +ATOM 4314 CG2 THR C 65 12.654 -26.525 49.432 1.00108.45 C +ATOM 4315 N ALA C 66 10.433 -29.420 48.096 1.00 92.60 N +ATOM 4316 CA ALA C 66 9.225 -29.303 47.316 1.00103.47 C +ATOM 4317 C ALA C 66 8.100 -30.079 47.978 1.00 86.49 C +ATOM 4318 O ALA C 66 6.922 -29.674 47.904 1.00 62.40 O +ATOM 4319 CB ALA C 66 9.479 -29.786 45.897 1.00141.43 C +ATOM 4320 N MET C 67 8.472 -31.194 48.620 1.00 82.71 N +ATOM 4321 CA MET C 67 7.494 -32.032 49.331 1.00 95.34 C +ATOM 4322 C MET C 67 6.893 -31.252 50.502 1.00106.17 C +ATOM 4323 O MET C 67 5.663 -31.261 50.725 1.00 85.25 O +ATOM 4324 CB MET C 67 8.128 -33.312 49.861 1.00 70.81 C +ATOM 4325 CG MET C 67 8.506 -34.339 48.804 1.00 62.81 C +ATOM 4326 SD MET C 67 9.552 -35.633 49.537 1.00 98.39 S +ATOM 4327 CE MET C 67 9.692 -36.787 48.171 1.00 77.59 C +ATOM 4328 N LEU C 68 7.750 -30.509 51.199 1.00103.16 N +ATOM 4329 CA LEU C 68 7.277 -29.670 52.300 1.00101.47 C +ATOM 4330 C LEU C 68 6.334 -28.566 51.814 1.00 82.30 C +ATOM 4331 O LEU C 68 5.300 -28.338 52.430 1.00 71.43 O +ATOM 4332 CB LEU C 68 8.438 -29.037 53.071 1.00 85.26 C +ATOM 4333 CG LEU C 68 7.964 -27.994 54.098 1.00 76.34 C +ATOM 4334 CD1 LEU C 68 7.180 -28.647 55.219 1.00 84.95 C +ATOM 4335 CD2 LEU C 68 9.130 -27.216 54.672 1.00 82.45 C +ATOM 4336 N VAL C 69 6.702 -27.895 50.721 1.00 70.94 N +ATOM 4337 CA VAL C 69 5.892 -26.820 50.192 1.00 77.90 C +ATOM 4338 C VAL C 69 4.530 -27.376 49.782 1.00104.95 C +ATOM 4339 O VAL C 69 3.477 -26.791 50.099 1.00147.52 O +ATOM 4340 CB VAL C 69 6.527 -26.148 48.974 1.00 76.22 C +ATOM 4341 CG1 VAL C 69 5.535 -25.164 48.360 1.00117.41 C +ATOM 4342 CG2 VAL C 69 7.795 -25.399 49.334 1.00 67.86 C +ATOM 4343 N THR C 70 4.550 -28.524 49.121 1.00100.83 N +ATOM 4344 CA THR C 70 3.319 -29.185 48.726 1.00118.14 C +ATOM 4345 C THR C 70 2.458 -29.576 49.929 1.00112.55 C +ATOM 4346 O THR C 70 1.229 -29.357 49.932 1.00118.43 O +ATOM 4347 CB THR C 70 3.632 -30.431 47.892 1.00149.44 C +ATOM 4348 OG1 THR C 70 4.464 -30.036 46.794 1.00159.34 O +ATOM 4349 CG2 THR C 70 2.334 -31.085 47.361 1.00165.24 C +ATOM 4350 N ALA C 71 3.086 -30.164 50.948 1.00103.43 N +ATOM 4351 CA ALA C 71 2.358 -30.518 52.174 1.00113.19 C +ATOM 4352 C ALA C 71 1.758 -29.280 52.875 1.00107.26 C +ATOM 4353 O ALA C 71 0.589 -29.295 53.311 1.00102.77 O +ATOM 4354 CB ALA C 71 3.265 -31.261 53.135 1.00 95.84 C +ATOM 4355 N LEU C 72 2.539 -28.206 52.934 1.00 96.20 N +ATOM 4356 CA LEU C 72 2.045 -26.933 53.465 1.00 92.70 C +ATOM 4357 C LEU C 72 0.830 -26.399 52.695 1.00103.52 C +ATOM 4358 O LEU C 72 -0.002 -25.680 53.254 1.00 89.15 O +ATOM 4359 CB LEU C 72 3.144 -25.868 53.458 1.00 73.27 C +ATOM 4360 CG LEU C 72 4.292 -26.160 54.403 1.00 78.53 C +ATOM 4361 CD1 LEU C 72 5.455 -25.299 54.015 1.00 92.14 C +ATOM 4362 CD2 LEU C 72 3.916 -25.892 55.848 1.00106.54 C +ATOM 4363 N LYS C 73 0.729 -26.747 51.415 1.00108.50 N +ATOM 4364 CA LYS C 73 -0.400 -26.292 50.613 1.00110.27 C +ATOM 4365 C LYS C 73 -1.618 -27.182 50.774 1.00108.37 C +ATOM 4366 O LYS C 73 -2.727 -26.691 50.942 1.00 99.88 O +ATOM 4367 CB LYS C 73 -0.030 -26.242 49.145 1.00112.98 C +ATOM 4368 CG LYS C 73 -1.082 -25.546 48.319 1.00117.26 C +ATOM 4369 CD LYS C 73 -1.041 -26.075 46.914 1.00128.27 C +ATOM 4370 CE LYS C 73 -1.748 -27.439 46.724 1.00113.54 C +ATOM 4371 NZ LYS C 73 -3.065 -27.290 46.037 1.00118.64 N +ATOM 4372 N ASP C 74 -1.401 -28.493 50.718 1.00107.44 N +ATOM 4373 CA ASP C 74 -2.488 -29.460 50.829 1.00105.89 C +ATOM 4374 C ASP C 74 -3.247 -29.328 52.155 1.00112.17 C +ATOM 4375 O ASP C 74 -4.447 -29.628 52.213 1.00153.03 O +ATOM 4376 CB ASP C 74 -1.960 -30.899 50.681 1.00108.90 C +ATOM 4377 CG ASP C 74 -1.456 -31.213 49.265 1.00113.75 C +ATOM 4378 OD1 ASP C 74 -1.938 -30.601 48.272 1.00 94.58 O +ATOM 4379 OD2 ASP C 74 -0.564 -32.085 49.168 1.00 92.16 O +ATOM 4380 N SER C 75 -2.560 -28.866 53.202 1.00105.22 N +ATOM 4381 CA SER C 75 -3.153 -28.728 54.545 1.00100.66 C +ATOM 4382 C SER C 75 -4.275 -27.697 54.598 1.00 99.11 C +ATOM 4383 O SER C 75 -5.157 -27.781 55.454 1.00118.49 O +ATOM 4384 CB SER C 75 -2.088 -28.334 55.571 1.00 94.78 C +ATOM 4385 OG SER C 75 -1.908 -26.928 55.602 1.00 74.44 O +ATOM 4386 N ARG C 76 -4.236 -26.740 53.672 1.00113.01 N +ATOM 4387 CA ARG C 76 -5.213 -25.648 53.585 1.00127.88 C +ATOM 4388 C ARG C 76 -5.141 -24.773 54.811 1.00123.81 C +ATOM 4389 O ARG C 76 -6.153 -24.278 55.301 1.00151.08 O +ATOM 4390 CB ARG C 76 -6.633 -26.173 53.374 1.00134.63 C +ATOM 4391 CG ARG C 76 -6.836 -26.960 52.085 1.00146.27 C +ATOM 4392 CD ARG C 76 -8.288 -27.403 51.957 1.00158.28 C +ATOM 4393 NE ARG C 76 -8.639 -28.426 52.944 1.00158.01 N +ATOM 4394 CZ ARG C 76 -9.205 -28.192 54.128 1.00163.26 C +ATOM 4395 NH1 ARG C 76 -9.497 -26.955 54.526 1.00169.25 N +ATOM 4396 NH2 ARG C 76 -9.474 -29.212 54.926 1.00162.64 N +ATOM 4397 N TRP C 77 -3.924 -24.623 55.316 1.00119.06 N +ATOM 4398 CA TRP C 77 -3.632 -23.681 56.380 1.00126.71 C +ATOM 4399 C TRP C 77 -2.715 -22.567 55.869 1.00131.12 C +ATOM 4400 O TRP C 77 -2.785 -21.424 56.328 1.00107.92 O +ATOM 4401 CB TRP C 77 -2.967 -24.424 57.547 1.00133.14 C +ATOM 4402 CG TRP C 77 -3.922 -24.915 58.596 1.00138.78 C +ATOM 4403 CD1 TRP C 77 -4.748 -25.992 58.512 1.00126.17 C +ATOM 4404 CD2 TRP C 77 -4.129 -24.349 59.894 1.00138.39 C +ATOM 4405 NE1 TRP C 77 -5.481 -26.116 59.663 1.00105.52 N +ATOM 4406 CE2 TRP C 77 -5.116 -25.117 60.528 1.00117.70 C +ATOM 4407 CE3 TRP C 77 -3.590 -23.247 60.571 1.00142.52 C +ATOM 4408 CZ2 TRP C 77 -5.567 -24.829 61.805 1.00127.86 C +ATOM 4409 CZ3 TRP C 77 -4.050 -22.959 61.842 1.00121.48 C +ATOM 4410 CH2 TRP C 77 -5.023 -23.748 62.447 1.00115.85 C +ATOM 4411 N PHE C 78 -1.811 -22.937 54.957 1.00140.71 N +ATOM 4412 CA PHE C 78 -0.746 -22.053 54.474 1.00118.35 C +ATOM 4413 C PHE C 78 -0.838 -21.790 52.960 1.00121.59 C +ATOM 4414 O PHE C 78 -1.142 -22.700 52.173 1.00122.56 O +ATOM 4415 CB PHE C 78 0.622 -22.682 54.743 1.00104.31 C +ATOM 4416 CG PHE C 78 0.865 -23.043 56.174 1.00101.05 C +ATOM 4417 CD1 PHE C 78 1.148 -22.071 57.118 1.00109.34 C +ATOM 4418 CD2 PHE C 78 0.833 -24.360 56.567 1.00 95.95 C +ATOM 4419 CE1 PHE C 78 1.359 -22.407 58.439 1.00116.77 C +ATOM 4420 CE2 PHE C 78 1.070 -24.708 57.881 1.00103.61 C +ATOM 4421 CZ PHE C 78 1.336 -23.732 58.820 1.00107.60 C +ATOM 4422 N ILE C 79 -0.516 -20.557 52.564 1.00121.92 N +ATOM 4423 CA ILE C 79 -0.176 -20.214 51.179 1.00108.95 C +ATOM 4424 C ILE C 79 1.358 -20.188 51.073 1.00105.64 C +ATOM 4425 O ILE C 79 2.005 -19.517 51.880 1.00 73.06 O +ATOM 4426 CB ILE C 79 -0.677 -18.813 50.826 1.00100.39 C +ATOM 4427 CG1 ILE C 79 -2.136 -18.643 51.226 1.00120.59 C +ATOM 4428 CG2 ILE C 79 -0.513 -18.545 49.343 1.00102.76 C +ATOM 4429 CD1 ILE C 79 -2.542 -17.195 51.433 1.00155.24 C +ATOM 4430 N PRO C 80 1.936 -21.003 50.163 1.00102.55 N +ATOM 4431 CA PRO C 80 3.379 -20.992 50.094 1.00 90.20 C +ATOM 4432 C PRO C 80 3.824 -20.011 49.070 1.00112.78 C +ATOM 4433 O PRO C 80 3.184 -19.886 48.013 1.00114.50 O +ATOM 4434 CB PRO C 80 3.730 -22.387 49.642 1.00 83.71 C +ATOM 4435 CG PRO C 80 2.580 -23.214 50.065 1.00122.72 C +ATOM 4436 CD PRO C 80 1.404 -22.324 49.785 1.00123.33 C +ATOM 4437 N LEU C 81 4.799 -19.196 49.456 1.00106.84 N +ATOM 4438 CA LEU C 81 5.363 -18.216 48.565 1.00 79.23 C +ATOM 4439 C LEU C 81 6.579 -18.842 47.958 1.00 69.26 C +ATOM 4440 O LEU C 81 7.287 -19.604 48.651 1.00 59.27 O +ATOM 4441 CB LEU C 81 5.695 -16.939 49.306 1.00 60.04 C +ATOM 4442 CG LEU C 81 4.468 -16.357 49.989 1.00 72.19 C +ATOM 4443 CD1 LEU C 81 4.871 -15.146 50.779 1.00 53.10 C +ATOM 4444 CD2 LEU C 81 3.398 -15.974 48.961 1.00100.26 C +ATOM 4445 N GLU C 82 6.724 -18.614 46.639 1.00 64.20 N +ATOM 4446 CA GLU C 82 7.774 -19.237 45.837 1.00 62.64 C +ATOM 4447 C GLU C 82 9.148 -18.551 46.052 1.00 70.29 C +ATOM 4448 O GLU C 82 9.360 -17.404 45.676 1.00 35.15 O +ATOM 4449 CB GLU C 82 7.426 -19.255 44.359 1.00 51.40 C +ATOM 4450 CG GLU C 82 8.502 -19.894 43.504 1.00 70.13 C +ATOM 4451 CD GLU C 82 8.618 -21.433 43.676 1.00 89.62 C +ATOM 4452 OE1 GLU C 82 8.767 -21.965 44.822 1.00 72.83 O +ATOM 4453 OE2 GLU C 82 8.753 -22.120 42.624 1.00125.51 O +ATOM 4454 N ARG C 83 10.012 -19.265 46.785 1.00 86.67 N +ATOM 4455 CA ARG C 83 11.364 -18.838 47.041 1.00 68.44 C +ATOM 4456 C ARG C 83 12.393 -19.876 46.564 1.00 74.98 C +ATOM 4457 O ARG C 83 13.544 -19.515 46.322 1.00109.28 O +ATOM 4458 CB ARG C 83 11.569 -18.551 48.538 1.00 73.33 C +ATOM 4459 CG ARG C 83 10.616 -17.523 49.114 1.00 66.80 C +ATOM 4460 CD ARG C 83 10.878 -16.127 48.571 1.00 65.33 C +ATOM 4461 NE ARG C 83 10.097 -15.162 49.334 1.00 89.17 N +ATOM 4462 CZ ARG C 83 8.917 -14.634 48.962 1.00124.42 C +ATOM 4463 NH1 ARG C 83 8.413 -14.848 47.747 1.00107.73 N +ATOM 4464 NH2 ARG C 83 8.267 -13.834 49.809 1.00136.09 N +ATOM 4465 N GLN C 84 12.020 -21.144 46.404 1.00 67.36 N +ATOM 4466 CA GLN C 84 12.996 -22.099 45.879 1.00 79.73 C +ATOM 4467 C GLN C 84 13.534 -21.626 44.518 1.00 84.68 C +ATOM 4468 O GLN C 84 14.711 -21.712 44.245 1.00 88.59 O +ATOM 4469 CB GLN C 84 12.429 -23.524 45.783 1.00110.94 C +ATOM 4470 CG GLN C 84 13.475 -24.630 45.992 1.00122.78 C +ATOM 4471 CD GLN C 84 12.907 -26.039 45.804 1.00141.50 C +ATOM 4472 OE1 GLN C 84 11.756 -26.301 46.130 1.00110.60 O +ATOM 4473 NE2 GLN C 84 13.709 -26.934 45.237 1.00156.44 N +ATOM 4474 N GLY C 85 12.671 -21.113 43.654 1.00 93.17 N +ATOM 4475 CA GLY C 85 13.137 -20.637 42.359 1.00 83.77 C +ATOM 4476 C GLY C 85 13.067 -19.118 42.262 1.00 84.99 C +ATOM 4477 O GLY C 85 12.731 -18.581 41.209 1.00 65.75 O +ATOM 4478 N LEU C 86 13.465 -18.416 43.323 1.00 81.60 N +ATOM 4479 CA LEU C 86 13.216 -16.975 43.414 1.00 71.72 C +ATOM 4480 C LEU C 86 13.877 -16.242 42.276 1.00 75.25 C +ATOM 4481 O LEU C 86 13.370 -15.216 41.795 1.00 81.16 O +ATOM 4482 CB LEU C 86 13.703 -16.412 44.765 1.00 66.23 C +ATOM 4483 CG LEU C 86 13.712 -14.900 45.040 1.00 54.42 C +ATOM 4484 CD1 LEU C 86 12.341 -14.276 44.903 1.00 62.13 C +ATOM 4485 CD2 LEU C 86 14.250 -14.608 46.432 1.00 53.76 C +ATOM 4486 N GLN C 87 15.044 -16.736 41.872 1.00 84.55 N +ATOM 4487 CA GLN C 87 15.851 -16.024 40.890 1.00 93.21 C +ATOM 4488 C GLN C 87 15.091 -15.885 39.557 1.00 68.77 C +ATOM 4489 O GLN C 87 15.068 -14.796 38.923 1.00 62.77 O +ATOM 4490 CB GLN C 87 17.209 -16.718 40.718 1.00 87.36 C +ATOM 4491 CG GLN C 87 18.343 -15.741 40.421 1.00 97.39 C +ATOM 4492 CD GLN C 87 18.253 -14.451 41.269 1.00 94.08 C +ATOM 4493 OE1 GLN C 87 18.349 -14.511 42.500 1.00 98.26 O +ATOM 4494 NE2 GLN C 87 18.176 -13.281 40.606 1.00 64.33 N +ATOM 4495 N ASN C 88 14.433 -16.962 39.166 1.00 51.98 N +ATOM 4496 CA ASN C 88 13.666 -16.962 37.929 1.00 74.82 C +ATOM 4497 C ASN C 88 12.472 -16.027 38.003 1.00 75.68 C +ATOM 4498 O ASN C 88 12.068 -15.419 36.997 1.00114.27 O +ATOM 4499 CB ASN C 88 13.161 -18.361 37.620 1.00 78.77 C +ATOM 4500 CG ASN C 88 14.274 -19.369 37.529 1.00 86.89 C +ATOM 4501 OD1 ASN C 88 15.344 -19.064 37.027 1.00 77.43 O +ATOM 4502 ND2 ASN C 88 14.038 -20.572 38.064 1.00121.22 N +ATOM 4503 N LEU C 89 11.900 -15.937 39.190 1.00 62.37 N +ATOM 4504 CA LEU C 89 10.723 -15.130 39.399 1.00 59.69 C +ATOM 4505 C LEU C 89 11.097 -13.683 39.217 1.00 70.55 C +ATOM 4506 O LEU C 89 10.427 -12.911 38.505 1.00 93.71 O +ATOM 4507 CB LEU C 89 10.246 -15.372 40.812 1.00 59.18 C +ATOM 4508 CG LEU C 89 8.768 -15.205 41.114 1.00 55.36 C +ATOM 4509 CD1 LEU C 89 8.568 -14.074 42.088 1.00 48.62 C +ATOM 4510 CD2 LEU C 89 7.942 -14.984 39.861 1.00 53.43 C +ATOM 4511 N LEU C 90 12.266 -13.332 39.739 1.00 76.65 N +ATOM 4512 CA LEU C 90 12.767 -11.951 39.613 1.00 90.57 C +ATOM 4513 C LEU C 90 13.162 -11.603 38.162 1.00 94.08 C +ATOM 4514 O LEU C 90 13.039 -10.449 37.713 1.00 66.12 O +ATOM 4515 CB LEU C 90 13.965 -11.741 40.541 1.00 83.42 C +ATOM 4516 CG LEU C 90 13.676 -11.976 42.015 1.00 69.82 C +ATOM 4517 CD1 LEU C 90 14.979 -12.193 42.754 1.00 51.10 C +ATOM 4518 CD2 LEU C 90 12.891 -10.791 42.564 1.00 96.05 C +ATOM 4519 N ASN C 91 13.632 -12.618 37.443 1.00 83.54 N +ATOM 4520 CA ASN C 91 13.972 -12.461 36.053 1.00 83.13 C +ATOM 4521 C ASN C 91 12.735 -12.158 35.205 1.00 94.69 C +ATOM 4522 O ASN C 91 12.745 -11.254 34.364 1.00 75.37 O +ATOM 4523 CB ASN C 91 14.689 -13.718 35.549 1.00 74.10 C +ATOM 4524 CG ASN C 91 15.993 -13.385 34.912 1.00 98.53 C +ATOM 4525 OD1 ASN C 91 16.764 -12.570 35.484 1.00134.54 O +ATOM 4526 ND2 ASN C 91 16.153 -13.773 33.632 1.00101.83 N +ATOM 4527 N GLU C 92 11.695 -12.974 35.360 1.00113.30 N +ATOM 4528 CA GLU C 92 10.470 -12.766 34.594 1.00103.16 C +ATOM 4529 C GLU C 92 9.946 -11.358 34.860 1.00103.98 C +ATOM 4530 O GLU C 92 9.357 -10.714 33.988 1.00 67.83 O +ATOM 4531 CB GLU C 92 9.421 -13.834 34.941 1.00 90.30 C +ATOM 4532 CG GLU C 92 9.421 -15.029 34.004 1.00101.43 C +ATOM 4533 CD GLU C 92 9.320 -14.644 32.511 1.00113.10 C +ATOM 4534 OE1 GLU C 92 8.334 -13.981 32.072 1.00 76.42 O +ATOM 4535 OE2 GLU C 92 10.211 -15.078 31.743 1.00127.90 O +ATOM 4536 N ARG C 93 10.113 -10.911 36.098 1.00106.58 N +ATOM 4537 CA ARG C 93 9.625 -9.604 36.477 1.00115.05 C +ATOM 4538 C ARG C 93 10.464 -8.518 35.808 1.00112.54 C +ATOM 4539 O ARG C 93 9.938 -7.462 35.432 1.00 89.40 O +ATOM 4540 CB ARG C 93 9.573 -9.488 38.008 1.00105.89 C +ATOM 4541 CG ARG C 93 8.459 -10.360 38.592 1.00102.64 C +ATOM 4542 CD ARG C 93 8.557 -10.558 40.088 1.00108.72 C +ATOM 4543 NE ARG C 93 7.635 -9.693 40.811 1.00 77.63 N +ATOM 4544 CZ ARG C 93 7.947 -8.496 41.307 1.00 58.61 C +ATOM 4545 NH1 ARG C 93 9.161 -7.982 41.192 1.00 60.34 N +ATOM 4546 NH2 ARG C 93 7.038 -7.863 42.007 1.00 56.99 N +ATOM 4547 N LYS C 94 11.754 -8.788 35.614 1.00106.62 N +ATOM 4548 CA LYS C 94 12.609 -7.858 34.858 1.00 89.27 C +ATOM 4549 C LYS C 94 12.133 -7.755 33.408 1.00 74.77 C +ATOM 4550 O LYS C 94 12.066 -6.648 32.849 1.00 56.47 O +ATOM 4551 CB LYS C 94 14.052 -8.329 34.845 1.00 85.01 C +ATOM 4552 CG LYS C 94 14.918 -7.866 36.001 1.00 87.01 C +ATOM 4553 CD LYS C 94 16.263 -8.576 35.953 1.00 97.39 C +ATOM 4554 CE LYS C 94 17.344 -7.852 36.737 1.00101.16 C +ATOM 4555 NZ LYS C 94 18.516 -8.749 36.938 1.00113.18 N +ATOM 4556 N ILE C 95 11.721 -8.895 32.843 1.00 60.27 N +ATOM 4557 CA ILE C 95 11.332 -8.917 31.441 1.00 51.11 C +ATOM 4558 C ILE C 95 10.021 -8.224 31.253 1.00 54.46 C +ATOM 4559 O ILE C 95 9.809 -7.517 30.224 1.00 31.50 O +ATOM 4560 CB ILE C 95 11.190 -10.322 30.871 1.00 47.46 C +ATOM 4561 CG1 ILE C 95 12.402 -11.190 31.217 1.00 60.92 C +ATOM 4562 CG2 ILE C 95 11.112 -10.192 29.353 1.00 43.72 C +ATOM 4563 CD1 ILE C 95 12.547 -12.494 30.424 1.00 54.26 C +ATOM 4564 N ILE C 96 9.125 -8.460 32.242 1.00 54.70 N +ATOM 4565 CA ILE C 96 7.837 -7.771 32.296 1.00 51.96 C +ATOM 4566 C ILE C 96 8.023 -6.268 32.306 1.00 45.60 C +ATOM 4567 O ILE C 96 7.574 -5.570 31.387 1.00 38.05 O +ATOM 4568 CB ILE C 96 7.017 -8.156 33.509 1.00 45.22 C +ATOM 4569 CG1 ILE C 96 6.559 -9.612 33.411 1.00 51.48 C +ATOM 4570 CG2 ILE C 96 5.768 -7.281 33.550 1.00 50.62 C +ATOM 4571 CD1 ILE C 96 5.661 -10.056 34.558 1.00 53.11 C +ATOM 4572 N ARG C 97 8.740 -5.792 33.306 1.00 46.14 N +ATOM 4573 CA ARG C 97 8.959 -4.357 33.446 1.00 60.97 C +ATOM 4574 C ARG C 97 9.633 -3.756 32.205 1.00 71.86 C +ATOM 4575 O ARG C 97 9.419 -2.579 31.877 1.00 99.30 O +ATOM 4576 CB ARG C 97 9.790 -4.046 34.701 1.00 70.93 C +ATOM 4577 CG ARG C 97 8.989 -3.538 35.897 1.00 67.73 C +ATOM 4578 CD ARG C 97 9.902 -3.199 37.079 1.00 71.57 C +ATOM 4579 NE ARG C 97 10.308 -4.360 37.868 1.00 75.84 N +ATOM 4580 CZ ARG C 97 9.717 -4.760 38.989 1.00 83.21 C +ATOM 4581 NH1 ARG C 97 8.711 -4.080 39.501 1.00 65.01 N +ATOM 4582 NH2 ARG C 97 10.129 -5.878 39.583 1.00112.89 N +ATOM 4583 N ALA C 98 10.473 -4.536 31.534 1.00 69.31 N +ATOM 4584 CA ALA C 98 11.156 -4.035 30.366 1.00 79.49 C +ATOM 4585 C ALA C 98 10.179 -3.978 29.191 1.00 82.95 C +ATOM 4586 O ALA C 98 10.363 -3.176 28.258 1.00 59.44 O +ATOM 4587 CB ALA C 98 12.353 -4.919 30.056 1.00107.17 C +ATOM 4588 N ALA C 99 9.171 -4.867 29.220 1.00 87.05 N +ATOM 4589 CA ALA C 99 8.135 -4.983 28.142 1.00 78.44 C +ATOM 4590 C ALA C 99 7.173 -3.839 28.101 1.00 86.02 C +ATOM 4591 O ALA C 99 7.054 -3.138 27.089 1.00147.84 O +ATOM 4592 CB ALA C 99 7.334 -6.222 28.316 1.00 65.57 C +ATOM 4593 N GLN C 100 6.665 -3.497 29.274 1.00106.89 N +ATOM 4594 CA GLN C 100 5.575 -2.526 29.357 1.00121.85 C +ATOM 4595 C GLN C 100 5.937 -1.114 29.864 1.00119.50 C +ATOM 4596 O GLN C 100 5.048 -0.280 30.076 1.00120.70 O +ATOM 4597 CB GLN C 100 4.448 -3.111 30.202 1.00115.25 C +ATOM 4598 CG GLN C 100 4.893 -3.784 31.484 1.00 93.22 C +ATOM 4599 CD GLN C 100 3.929 -4.862 31.914 1.00 79.36 C +ATOM 4600 OE1 GLN C 100 3.725 -5.886 31.216 1.00 70.26 O +ATOM 4601 NE2 GLN C 100 3.393 -4.688 33.105 1.00 70.48 N +ATOM 4602 N GLU C 101 7.229 -0.837 30.037 1.00107.44 N +ATOM 4603 CA GLU C 101 7.662 0.457 30.573 1.00106.81 C +ATOM 4604 C GLU C 101 7.396 1.609 29.607 1.00108.86 C +ATOM 4605 O GLU C 101 7.283 2.765 30.029 1.00 83.23 O +ATOM 4606 CB GLU C 101 9.143 0.423 30.956 1.00114.01 C +ATOM 4607 CG GLU C 101 10.074 -0.086 29.861 1.00110.43 C +ATOM 4608 CD GLU C 101 11.537 -0.029 30.272 1.00116.30 C +ATOM 4609 OE1 GLU C 101 11.814 0.100 31.488 1.00111.16 O +ATOM 4610 OE2 GLU C 101 12.418 -0.070 29.379 1.00130.49 O +ATOM 4611 N ASN C 102 7.280 1.301 28.317 1.00110.52 N +ATOM 4612 CA ASN C 102 7.075 2.338 27.315 1.00106.47 C +ATOM 4613 C ASN C 102 5.612 2.584 26.990 1.00110.33 C +ATOM 4614 O ASN C 102 5.296 3.488 26.209 1.00120.28 O +ATOM 4615 CB ASN C 102 7.813 1.982 26.042 1.00103.72 C +ATOM 4616 CG ASN C 102 9.305 2.105 26.199 1.00119.47 C +ATOM 4617 OD1 ASN C 102 9.869 3.216 26.158 1.00124.50 O +ATOM 4618 ND2 ASN C 102 9.961 0.971 26.414 1.00129.46 N +ATOM 4619 N GLY C 103 4.715 1.816 27.604 1.00 95.13 N +ATOM 4620 CA GLY C 103 3.289 2.003 27.371 1.00 94.89 C +ATOM 4621 C GLY C 103 2.887 1.812 25.918 1.00 98.95 C +ATOM 4622 O GLY C 103 1.963 2.468 25.409 1.00112.13 O +ATOM 4623 N THR C 104 3.581 0.914 25.239 1.00 84.76 N +ATOM 4624 CA THR C 104 3.131 0.470 23.945 1.00 81.76 C +ATOM 4625 C THR C 104 2.407 -0.866 24.089 1.00 77.74 C +ATOM 4626 O THR C 104 1.543 -1.177 23.281 1.00100.47 O +ATOM 4627 CB THR C 104 4.291 0.368 22.925 1.00 73.89 C +ATOM 4628 OG1 THR C 104 5.220 -0.650 23.326 1.00 69.29 O +ATOM 4629 CG2 THR C 104 4.994 1.705 22.787 1.00 63.21 C +ATOM 4630 N VAL C 105 2.732 -1.640 25.116 1.00 77.46 N +ATOM 4631 CA VAL C 105 2.234 -3.025 25.202 1.00104.83 C +ATOM 4632 C VAL C 105 0.713 -3.029 25.278 1.00116.52 C +ATOM 4633 O VAL C 105 0.105 -2.164 25.927 1.00100.08 O +ATOM 4634 CB VAL C 105 2.866 -3.844 26.380 1.00132.48 C +ATOM 4635 CG1 VAL C 105 1.871 -4.832 26.988 1.00103.04 C +ATOM 4636 CG2 VAL C 105 4.131 -4.591 25.916 1.00142.84 C +ATOM 4637 N ALA C 106 0.126 -3.998 24.575 1.00126.38 N +ATOM 4638 CA ALA C 106 -1.313 -4.077 24.366 1.00125.76 C +ATOM 4639 C ALA C 106 -2.043 -4.256 25.690 1.00157.66 C +ATOM 4640 O ALA C 106 -1.644 -5.071 26.526 1.00155.51 O +ATOM 4641 CB ALA C 106 -1.635 -5.226 23.423 1.00113.42 C +ATOM 4642 N ILE C 107 -3.115 -3.487 25.871 1.00170.99 N +ATOM 4643 CA ILE C 107 -3.834 -3.427 27.150 1.00160.80 C +ATOM 4644 C ILE C 107 -4.379 -4.803 27.598 1.00139.79 C +ATOM 4645 O ILE C 107 -4.471 -5.093 28.790 1.00110.41 O +ATOM 4646 CB ILE C 107 -4.977 -2.381 27.077 1.00130.46 C +ATOM 4647 CG1 ILE C 107 -5.540 -2.087 28.474 1.00123.85 C +ATOM 4648 CG2 ILE C 107 -6.079 -2.853 26.136 1.00123.21 C +ATOM 4649 CD1 ILE C 107 -4.521 -1.592 29.483 1.00108.22 C +ATOM 4650 N ASN C 108 -4.716 -5.648 26.629 1.00139.11 N +ATOM 4651 CA ASN C 108 -5.136 -7.029 26.900 1.00139.17 C +ATOM 4652 C ASN C 108 -3.970 -7.881 27.386 1.00133.43 C +ATOM 4653 O ASN C 108 -4.137 -8.777 28.214 1.00146.55 O +ATOM 4654 CB ASN C 108 -5.707 -7.671 25.633 1.00165.72 C +ATOM 4655 CG ASN C 108 -6.364 -6.659 24.710 1.00194.14 C +ATOM 4656 OD1 ASN C 108 -7.543 -6.350 24.855 1.00221.37 O +ATOM 4657 ND2 ASN C 108 -5.599 -6.141 23.750 1.00201.00 N +ATOM 4658 N ASN C 109 -2.790 -7.601 26.845 1.00116.14 N +ATOM 4659 CA ASN C 109 -1.596 -8.390 27.112 1.00135.87 C +ATOM 4660 C ASN C 109 -0.843 -7.941 28.373 1.00141.33 C +ATOM 4661 O ASN C 109 -0.011 -8.691 28.912 1.00120.71 O +ATOM 4662 CB ASN C 109 -0.659 -8.319 25.904 1.00143.92 C +ATOM 4663 CG ASN C 109 -0.460 -9.664 25.237 1.00154.70 C +ATOM 4664 OD1 ASN C 109 0.639 -10.225 25.267 1.00127.28 O +ATOM 4665 ND2 ASN C 109 -1.534 -10.217 24.680 1.00163.41 N +ATOM 4666 N ARG C 110 -1.155 -6.729 28.838 1.00134.60 N +ATOM 4667 CA ARG C 110 -0.446 -6.077 29.958 1.00115.13 C +ATOM 4668 C ARG C 110 -0.449 -6.941 31.229 1.00 95.66 C +ATOM 4669 O ARG C 110 -1.482 -7.511 31.592 1.00100.97 O +ATOM 4670 CB ARG C 110 -1.117 -4.732 30.263 1.00 95.94 C +ATOM 4671 CG ARG C 110 -0.229 -3.734 30.966 1.00103.62 C +ATOM 4672 CD ARG C 110 -0.549 -2.315 30.538 1.00113.11 C +ATOM 4673 NE ARG C 110 -1.586 -1.717 31.385 1.00111.13 N +ATOM 4674 CZ ARG C 110 -1.431 -0.615 32.127 1.00125.89 C +ATOM 4675 NH1 ARG C 110 -0.270 0.054 32.159 1.00126.31 N +ATOM 4676 NH2 ARG C 110 -2.461 -0.156 32.836 1.00130.53 N +ATOM 4677 N ILE C 111 0.695 -7.045 31.896 1.00 77.73 N +ATOM 4678 CA ILE C 111 0.757 -7.763 33.168 1.00 78.02 C +ATOM 4679 C ILE C 111 0.991 -6.787 34.290 1.00 85.97 C +ATOM 4680 O ILE C 111 2.041 -6.161 34.339 1.00 86.88 O +ATOM 4681 CB ILE C 111 1.882 -8.808 33.207 1.00 77.54 C +ATOM 4682 CG1 ILE C 111 1.606 -9.901 32.166 1.00100.34 C +ATOM 4683 CG2 ILE C 111 1.994 -9.419 34.601 1.00 62.59 C +ATOM 4684 CD1 ILE C 111 2.776 -10.834 31.895 1.00109.33 C +ATOM 4685 N PRO C 112 0.022 -6.668 35.212 1.00104.55 N +ATOM 4686 CA PRO C 112 0.165 -5.718 36.301 1.00 98.96 C +ATOM 4687 C PRO C 112 1.079 -6.283 37.393 1.00 91.10 C +ATOM 4688 O PRO C 112 0.875 -7.414 37.862 1.00 66.67 O +ATOM 4689 CB PRO C 112 -1.274 -5.555 36.792 1.00 99.29 C +ATOM 4690 CG PRO C 112 -1.900 -6.897 36.543 1.00 92.21 C +ATOM 4691 CD PRO C 112 -1.186 -7.507 35.369 1.00 97.61 C +ATOM 4692 N LEU C 113 2.056 -5.483 37.799 1.00102.74 N +ATOM 4693 CA LEU C 113 3.071 -5.926 38.741 1.00122.50 C +ATOM 4694 C LEU C 113 2.904 -5.308 40.114 1.00110.67 C +ATOM 4695 O LEU C 113 2.654 -4.105 40.279 1.00113.31 O +ATOM 4696 CB LEU C 113 4.477 -5.628 38.215 1.00130.39 C +ATOM 4697 CG LEU C 113 5.064 -6.694 37.299 1.00125.12 C +ATOM 4698 CD1 LEU C 113 6.482 -6.270 36.957 1.00119.08 C +ATOM 4699 CD2 LEU C 113 5.054 -8.087 37.921 1.00117.01 C +ATOM 4700 N GLN C 114 3.150 -6.148 41.099 1.00107.30 N +ATOM 4701 CA GLN C 114 2.844 -5.843 42.468 1.00130.57 C +ATOM 4702 C GLN C 114 3.977 -6.410 43.275 1.00127.97 C +ATOM 4703 O GLN C 114 4.629 -7.359 42.826 1.00187.62 O +ATOM 4704 CB GLN C 114 1.551 -6.536 42.846 1.00119.49 C +ATOM 4705 CG GLN C 114 0.757 -5.810 43.887 1.00112.02 C +ATOM 4706 CD GLN C 114 -0.080 -6.777 44.657 1.00128.32 C +ATOM 4707 OE1 GLN C 114 -0.515 -7.804 44.115 1.00112.17 O +ATOM 4708 NE2 GLN C 114 -0.319 -6.473 45.937 1.00174.58 N +ATOM 4709 N SER C 115 4.298 -5.758 44.385 1.00108.23 N +ATOM 4710 CA SER C 115 5.485 -6.109 45.157 1.00114.96 C +ATOM 4711 C SER C 115 5.368 -7.551 45.569 1.00106.36 C +ATOM 4712 O SER C 115 4.249 -8.110 45.616 1.00111.09 O +ATOM 4713 CB SER C 115 5.604 -5.220 46.397 1.00128.18 C +ATOM 4714 OG SER C 115 4.374 -5.177 47.116 1.00138.82 O +ATOM 4715 N LEU C 116 6.497 -8.188 45.858 1.00 93.08 N +ATOM 4716 CA LEU C 116 6.445 -9.644 46.013 1.00128.21 C +ATOM 4717 C LEU C 116 5.821 -9.936 47.359 1.00121.66 C +ATOM 4718 O LEU C 116 6.215 -9.323 48.340 1.00122.32 O +ATOM 4719 CB LEU C 116 7.831 -10.280 45.953 1.00147.73 C +ATOM 4720 CG LEU C 116 8.571 -10.230 44.608 1.00123.11 C +ATOM 4721 CD1 LEU C 116 9.513 -9.018 44.537 1.00118.14 C +ATOM 4722 CD2 LEU C 116 9.321 -11.533 44.426 1.00 82.53 C +ATOM 4723 N THR C 117 4.756 -10.733 47.367 1.00139.19 N +ATOM 4724 CA THR C 117 4.010 -11.016 48.592 1.00117.81 C +ATOM 4725 C THR C 117 5.018 -11.579 49.560 1.00111.62 C +ATOM 4726 O THR C 117 5.781 -12.468 49.188 1.00 92.80 O +ATOM 4727 CB THR C 117 2.880 -12.049 48.359 1.00114.49 C +ATOM 4728 OG1 THR C 117 2.002 -11.593 47.322 1.00 89.39 O +ATOM 4729 CG2 THR C 117 2.070 -12.250 49.621 1.00112.74 C +ATOM 4730 N ALA C 118 4.969 -11.095 50.799 1.00 94.19 N +ATOM 4731 CA ALA C 118 5.998 -11.407 51.792 1.00 73.15 C +ATOM 4732 C ALA C 118 5.462 -12.207 52.948 1.00 82.05 C +ATOM 4733 O ALA C 118 4.354 -11.948 53.443 1.00137.65 O +ATOM 4734 CB ALA C 118 6.603 -10.140 52.316 1.00 51.90 C +ATOM 4735 N ALA C 119 6.281 -13.133 53.418 1.00 94.07 N +ATOM 4736 CA ALA C 119 5.857 -14.129 54.407 1.00126.63 C +ATOM 4737 C ALA C 119 6.082 -13.616 55.809 1.00131.20 C +ATOM 4738 O ALA C 119 6.958 -12.762 56.007 1.00123.68 O +ATOM 4739 CB ALA C 119 6.628 -15.424 54.204 1.00133.37 C +ATOM 4740 N ASN C 120 5.311 -14.131 56.775 1.00111.89 N +ATOM 4741 CA ASN C 120 5.557 -13.781 58.163 1.00128.81 C +ATOM 4742 C ASN C 120 6.372 -14.825 58.898 1.00129.04 C +ATOM 4743 O ASN C 120 7.308 -14.504 59.659 1.00127.30 O +ATOM 4744 CB ASN C 120 4.274 -13.539 58.937 1.00140.57 C +ATOM 4745 CG ASN C 120 4.549 -13.063 60.371 1.00196.00 C +ATOM 4746 OD1 ASN C 120 3.889 -13.515 61.299 1.00267.60 O +ATOM 4747 ND2 ASN C 120 5.585 -12.216 60.567 1.00186.54 N +ATOM 4748 N ILE C 121 5.982 -16.078 58.740 1.00104.34 N +ATOM 4749 CA ILE C 121 6.782 -17.154 59.306 1.00132.26 C +ATOM 4750 C ILE C 121 7.404 -17.898 58.148 1.00143.15 C +ATOM 4751 O ILE C 121 6.813 -18.030 57.083 1.00143.08 O +ATOM 4752 CB ILE C 121 5.973 -18.122 60.204 1.00113.31 C +ATOM 4753 CG1 ILE C 121 5.047 -19.014 59.374 1.00125.99 C +ATOM 4754 CG2 ILE C 121 5.191 -17.346 61.249 1.00105.24 C +ATOM 4755 CD1 ILE C 121 5.467 -20.467 59.353 1.00128.48 C +ATOM 4756 N MET C 122 8.643 -18.325 58.327 1.00125.05 N +ATOM 4757 CA MET C 122 9.209 -19.233 57.370 1.00 74.60 C +ATOM 4758 C MET C 122 9.560 -20.496 58.119 1.00 52.51 C +ATOM 4759 O MET C 122 10.034 -20.449 59.237 1.00 45.20 O +ATOM 4760 CB MET C 122 10.378 -18.557 56.604 1.00 73.01 C +ATOM 4761 CG MET C 122 11.503 -17.985 57.442 1.00 61.24 C +ATOM 4762 SD MET C 122 12.997 -17.945 56.446 1.00 84.11 S +ATOM 4763 CE MET C 122 14.174 -18.606 57.688 1.00134.53 C +ATOM 4764 N VAL C 123 9.393 -21.617 57.455 1.00 51.85 N +ATOM 4765 CA VAL C 123 9.768 -22.898 58.032 1.00 69.62 C +ATOM 4766 C VAL C 123 10.852 -23.609 57.239 1.00 75.55 C +ATOM 4767 O VAL C 123 10.765 -23.754 56.020 1.00 91.59 O +ATOM 4768 CB VAL C 123 8.568 -23.843 58.088 1.00100.91 C +ATOM 4769 CG1 VAL C 123 7.733 -23.742 56.815 1.00117.82 C +ATOM 4770 CG2 VAL C 123 9.007 -25.287 58.343 1.00113.65 C +ATOM 4771 N GLU C 124 11.899 -24.019 57.926 1.00 76.01 N +ATOM 4772 CA GLU C 124 12.958 -24.778 57.289 1.00 83.64 C +ATOM 4773 C GLU C 124 13.223 -26.002 58.100 1.00 83.21 C +ATOM 4774 O GLU C 124 12.792 -26.114 59.239 1.00110.86 O +ATOM 4775 CB GLU C 124 14.256 -23.954 57.116 1.00102.35 C +ATOM 4776 CG GLU C 124 14.504 -22.852 58.137 1.00114.46 C +ATOM 4777 CD GLU C 124 15.543 -21.854 57.660 1.00110.18 C +ATOM 4778 OE1 GLU C 124 15.564 -21.540 56.446 1.00122.78 O +ATOM 4779 OE2 GLU C 124 16.308 -21.357 58.498 1.00 91.84 O +ATOM 4780 N GLY C 125 14.040 -26.875 57.545 1.00 95.80 N +ATOM 4781 CA GLY C 125 14.346 -28.131 58.193 1.00 99.17 C +ATOM 4782 C GLY C 125 15.400 -28.915 57.436 1.00 92.90 C +ATOM 4783 O GLY C 125 16.165 -28.361 56.653 1.00 93.35 O +ATOM 4784 N SER C 126 15.468 -30.206 57.710 1.00 80.89 N +ATOM 4785 CA SER C 126 16.537 -31.020 57.174 1.00 79.85 C +ATOM 4786 C SER C 126 16.128 -32.458 57.244 1.00 88.81 C +ATOM 4787 O SER C 126 15.420 -32.863 58.164 1.00124.95 O +ATOM 4788 CB SER C 126 17.818 -30.838 57.975 1.00 87.22 C +ATOM 4789 OG SER C 126 17.956 -29.524 58.534 1.00135.23 O +ATOM 4790 N ILE C 127 16.581 -33.247 56.290 1.00 87.04 N +ATOM 4791 CA ILE C 127 16.513 -34.683 56.453 1.00 89.01 C +ATOM 4792 C ILE C 127 17.654 -35.106 57.370 1.00 98.79 C +ATOM 4793 O ILE C 127 18.807 -35.139 56.977 1.00133.47 O +ATOM 4794 CB ILE C 127 16.599 -35.437 55.124 1.00 94.45 C +ATOM 4795 CG1 ILE C 127 15.364 -35.144 54.263 1.00 88.28 C +ATOM 4796 CG2 ILE C 127 16.731 -36.941 55.369 1.00 95.97 C +ATOM 4797 CD1 ILE C 127 15.635 -35.198 52.764 1.00 92.17 C +ATOM 4798 N ILE C 128 17.313 -35.368 58.621 1.00 93.62 N +ATOM 4799 CA ILE C 128 18.268 -35.738 59.653 1.00 84.18 C +ATOM 4800 C ILE C 128 18.231 -37.244 59.621 1.00 72.74 C +ATOM 4801 O ILE C 128 17.319 -37.907 60.098 1.00 98.88 O +ATOM 4802 CB ILE C 128 17.873 -35.132 61.031 1.00106.75 C +ATOM 4803 CG1 ILE C 128 16.410 -35.461 61.394 1.00130.90 C +ATOM 4804 CG2 ILE C 128 17.932 -33.610 60.976 1.00117.63 C +ATOM 4805 CD1 ILE C 128 16.140 -35.432 62.888 1.00123.55 C +ATOM 4806 N GLY C 129 19.197 -37.809 58.948 1.00 93.62 N +ATOM 4807 CA GLY C 129 19.487 -39.231 59.130 1.00129.39 C +ATOM 4808 C GLY C 129 18.704 -40.227 58.280 1.00123.46 C +ATOM 4809 O GLY C 129 17.504 -40.103 58.051 1.00 81.20 O +ATOM 4810 N TYR C 130 19.459 -41.183 57.746 1.00136.84 N +ATOM 4811 CA TYR C 130 18.906 -42.394 57.151 1.00 92.90 C +ATOM 4812 C TYR C 130 19.850 -43.498 57.563 1.00109.00 C +ATOM 4813 O TYR C 130 21.002 -43.523 57.128 1.00157.13 O +ATOM 4814 CB TYR C 130 18.845 -42.276 55.622 1.00 94.82 C +ATOM 4815 CG TYR C 130 18.404 -43.515 54.901 1.00 77.56 C +ATOM 4816 CD1 TYR C 130 19.257 -44.606 54.783 1.00 79.40 C +ATOM 4817 CD2 TYR C 130 17.180 -43.555 54.236 1.00 84.75 C +ATOM 4818 CE1 TYR C 130 18.877 -45.734 54.066 1.00 94.37 C +ATOM 4819 CE2 TYR C 130 16.795 -44.666 53.505 1.00 92.95 C +ATOM 4820 CZ TYR C 130 17.635 -45.754 53.425 1.00 93.74 C +ATOM 4821 OH TYR C 130 17.203 -46.889 52.781 1.00 78.74 O +ATOM 4822 N GLU C 131 19.421 -44.316 58.510 1.00108.86 N +ATOM 4823 CA GLU C 131 20.201 -45.500 58.896 1.00108.28 C +ATOM 4824 C GLU C 131 19.594 -46.693 58.166 1.00 95.76 C +ATOM 4825 O GLU C 131 18.408 -46.680 57.822 1.00 70.66 O +ATOM 4826 CB GLU C 131 20.296 -45.724 60.433 1.00143.64 C +ATOM 4827 CG GLU C 131 21.464 -44.908 61.135 1.00197.43 C +ATOM 4828 CD GLU C 131 21.570 -43.442 60.652 1.00204.30 C +ATOM 4829 OE1 GLU C 131 20.556 -42.746 60.500 1.00227.34 O +ATOM 4830 OE2 GLU C 131 22.676 -42.935 60.452 1.00164.02 O +ATOM 4831 N SER C 132 20.451 -47.620 57.744 1.00114.94 N +ATOM 4832 CA SER C 132 20.029 -48.679 56.833 1.00118.12 C +ATOM 4833 C SER C 132 20.158 -50.047 57.496 1.00148.40 C +ATOM 4834 O SER C 132 21.142 -50.323 58.185 1.00157.78 O +ATOM 4835 CB SER C 132 20.828 -48.631 55.519 1.00111.52 C +ATOM 4836 OG SER C 132 21.682 -49.748 55.393 1.00103.19 O +ATOM 4837 N ASN C 133 19.175 -50.914 57.236 1.00159.27 N +ATOM 4838 CA ASN C 133 19.051 -52.211 57.923 1.00140.01 C +ATOM 4839 C ASN C 133 19.158 -52.045 59.428 1.00127.76 C +ATOM 4840 O ASN C 133 20.038 -52.620 60.073 1.00113.65 O +ATOM 4841 CB ASN C 133 20.092 -53.220 57.425 1.00142.64 C +ATOM 4842 CG ASN C 133 19.931 -53.555 55.948 1.00146.61 C +ATOM 4843 OD1 ASN C 133 18.837 -53.472 55.383 1.00179.74 O +ATOM 4844 ND2 ASN C 133 21.050 -53.859 55.309 1.00115.52 N +ATOM 4845 N VAL C 134 18.297 -51.180 59.955 1.00109.11 N +ATOM 4846 CA VAL C 134 18.265 -50.873 61.374 1.00102.37 C +ATOM 4847 C VAL C 134 17.780 -52.131 62.069 1.00126.17 C +ATOM 4848 O VAL C 134 18.253 -52.474 63.159 1.00189.58 O +ATOM 4849 CB VAL C 134 17.327 -49.684 61.676 1.00105.38 C +ATOM 4850 CG1 VAL C 134 17.333 -49.330 63.152 1.00111.71 C +ATOM 4851 CG2 VAL C 134 17.742 -48.462 60.861 1.00114.26 C +ATOM 4852 N LYS C 135 16.886 -52.857 61.401 1.00121.21 N +ATOM 4853 CA LYS C 135 16.618 -54.250 61.764 1.00112.28 C +ATOM 4854 C LYS C 135 16.553 -55.138 60.534 1.00126.56 C +ATOM 4855 O LYS C 135 16.289 -54.678 59.411 1.00159.72 O +ATOM 4856 CB LYS C 135 15.310 -54.351 62.536 1.00116.00 C +ATOM 4857 CG LYS C 135 15.327 -53.601 63.856 1.00141.39 C +ATOM 4858 CD LYS C 135 13.960 -53.646 64.514 1.00179.25 C +ATOM 4859 CE LYS C 135 13.942 -52.898 65.830 1.00186.41 C +ATOM 4860 NZ LYS C 135 12.808 -53.360 66.674 1.00177.30 N +ATOM 4861 N SER C 136 16.720 -56.432 60.763 1.00134.10 N +ATOM 4862 CA SER C 136 16.637 -57.413 59.688 1.00160.36 C +ATOM 4863 C SER C 136 16.466 -58.820 60.236 1.00152.64 C +ATOM 4864 O SER C 136 16.815 -59.095 61.384 1.00174.74 O +ATOM 4865 CB SER C 136 17.878 -57.341 58.793 1.00162.18 C +ATOM 4866 OG SER C 136 18.523 -58.603 58.696 1.00192.17 O +ATOM 4867 N GLY C 137 15.923 -59.706 59.411 1.00139.47 N +ATOM 4868 CA GLY C 137 15.733 -61.095 59.815 1.00153.11 C +ATOM 4869 C GLY C 137 15.380 -62.015 58.667 1.00167.85 C +ATOM 4870 O GLY C 137 15.182 -61.564 57.540 1.00196.73 O +ATOM 4871 N GLY C 138 15.329 -63.312 58.946 1.00182.88 N +ATOM 4872 CA GLY C 138 15.022 -64.296 57.916 1.00190.39 C +ATOM 4873 C GLY C 138 14.702 -65.657 58.489 1.00198.86 C +ATOM 4874 O GLY C 138 15.265 -66.066 59.507 1.00250.30 O +ATOM 4875 N VAL C 139 13.774 -66.352 57.840 1.00193.96 N +ATOM 4876 CA VAL C 139 13.390 -67.711 58.227 1.00180.29 C +ATOM 4877 C VAL C 139 13.183 -68.576 56.986 1.00182.45 C +ATOM 4878 O VAL C 139 12.420 -68.210 56.090 1.00217.11 O +ATOM 4879 CB VAL C 139 12.086 -67.730 59.047 1.00150.32 C +ATOM 4880 CG1 VAL C 139 11.661 -69.164 59.310 1.00133.23 C +ATOM 4881 CG2 VAL C 139 12.254 -66.968 60.358 1.00151.55 C +ATOM 4882 N GLY C 140 13.866 -69.718 56.941 1.00181.39 N +ATOM 4883 CA GLY C 140 13.785 -70.619 55.798 1.00172.69 C +ATOM 4884 C GLY C 140 13.982 -72.076 56.155 1.00186.45 C +ATOM 4885 O GLY C 140 14.777 -72.416 57.036 1.00196.80 O +ATOM 4886 N ALA C 141 13.234 -72.943 55.482 1.00200.99 N +ATOM 4887 CA ALA C 141 13.302 -74.375 55.745 1.00183.37 C +ATOM 4888 C ALA C 141 13.125 -75.190 54.466 1.00185.98 C +ATOM 4889 O ALA C 141 12.320 -74.849 53.591 1.00188.97 O +ATOM 4890 CB ALA C 141 12.273 -74.775 56.792 1.00146.81 C +ATOM 4891 N ARG C 142 13.930 -76.234 54.345 1.00186.59 N +ATOM 4892 CA ARG C 142 13.807 -77.147 53.236 1.00179.97 C +ATOM 4893 C ARG C 142 13.762 -78.569 53.777 1.00190.34 C +ATOM 4894 O ARG C 142 14.399 -78.887 54.784 1.00129.86 O +ATOM 4895 CB ARG C 142 14.960 -76.975 52.243 1.00163.56 C +ATOM 4896 CG ARG C 142 14.810 -77.864 51.021 1.00157.56 C +ATOM 4897 CD ARG C 142 15.187 -77.141 49.759 1.00164.02 C +ATOM 4898 NE ARG C 142 16.634 -77.043 49.735 1.00168.17 N +ATOM 4899 CZ ARG C 142 17.293 -76.051 49.147 1.00198.76 C +ATOM 4900 NH1 ARG C 142 16.672 -75.161 48.367 1.00210.05 N +ATOM 4901 NH2 ARG C 142 18.613 -76.022 49.231 1.00237.01 N +ATOM 4902 N TYR C 143 12.959 -79.406 53.123 1.00227.84 N +ATOM 4903 CA TYR C 143 12.663 -80.757 53.614 1.00205.12 C +ATOM 4904 C TYR C 143 12.849 -81.819 52.520 1.00178.19 C +ATOM 4905 O TYR C 143 11.903 -82.204 51.832 1.00117.15 O +ATOM 4906 CB TYR C 143 11.233 -80.799 54.167 1.00178.59 C +ATOM 4907 CG TYR C 143 10.879 -82.086 54.832 1.00168.92 C +ATOM 4908 CD1 TYR C 143 11.432 -82.422 56.060 1.00174.67 C +ATOM 4909 CD2 TYR C 143 10.017 -82.982 54.228 1.00163.08 C +ATOM 4910 CE1 TYR C 143 11.122 -83.618 56.679 1.00170.45 C +ATOM 4911 CE2 TYR C 143 9.691 -84.179 54.842 1.00170.20 C +ATOM 4912 CZ TYR C 143 10.249 -84.491 56.066 1.00169.25 C +ATOM 4913 OH TYR C 143 9.935 -85.679 56.683 1.00174.97 O +ATOM 4914 N GLY C 145 13.191 -82.119 49.816 1.00163.57 N +ATOM 4915 CA GLY C 145 12.988 -81.684 48.435 1.00174.92 C +ATOM 4916 C GLY C 145 12.247 -80.361 48.252 1.00175.71 C +ATOM 4917 O GLY C 145 12.457 -79.675 47.253 1.00126.79 O +ATOM 4918 N ILE C 146 11.431 -79.975 49.235 1.00195.86 N +ATOM 4919 CA ILE C 146 10.562 -78.791 49.125 1.00178.69 C +ATOM 4920 C ILE C 146 11.012 -77.730 50.138 1.00191.04 C +ATOM 4921 O ILE C 146 11.333 -78.056 51.277 1.00213.68 O +ATOM 4922 CB ILE C 146 9.077 -79.149 49.385 1.00170.86 C +ATOM 4923 CG1 ILE C 146 8.731 -80.503 48.750 1.00169.88 C +ATOM 4924 CG2 ILE C 146 8.154 -78.064 48.844 1.00174.77 C +ATOM 4925 CD1 ILE C 146 8.793 -81.672 49.712 1.00169.02 C +ATOM 4926 N GLY C 147 11.042 -76.461 49.736 1.00196.20 N +ATOM 4927 CA GLY C 147 11.541 -75.411 50.629 1.00177.69 C +ATOM 4928 C GLY C 147 10.948 -74.029 50.433 1.00164.12 C +ATOM 4929 O GLY C 147 10.468 -73.683 49.355 1.00163.90 O +ATOM 4930 N ALA C 148 11.009 -73.226 51.485 1.00164.49 N +ATOM 4931 CA ALA C 148 10.639 -71.824 51.390 1.00181.47 C +ATOM 4932 C ALA C 148 11.495 -70.985 52.333 1.00205.75 C +ATOM 4933 O ALA C 148 12.208 -71.519 53.191 1.00185.97 O +ATOM 4934 CB ALA C 148 9.154 -71.648 51.688 1.00143.69 C +ATOM 4935 N ASP C 149 11.442 -69.671 52.147 1.00222.44 N +ATOM 4936 CA ASP C 149 12.135 -68.752 53.037 1.00188.62 C +ATOM 4937 C ASP C 149 11.620 -67.324 52.853 1.00164.32 C +ATOM 4938 O ASP C 149 11.205 -66.937 51.758 1.00145.90 O +ATOM 4939 CB ASP C 149 13.649 -68.821 52.813 1.00167.20 C +ATOM 4940 CG ASP C 149 14.090 -68.020 51.628 1.00177.14 C +ATOM 4941 OD1 ASP C 149 13.864 -68.481 50.491 1.00173.40 O +ATOM 4942 OD2 ASP C 149 14.662 -66.930 51.832 1.00193.33 O +ATOM 4943 N THR C 150 11.608 -66.560 53.937 1.00146.88 N +ATOM 4944 CA THR C 150 11.456 -65.118 53.825 1.00152.17 C +ATOM 4945 C THR C 150 12.666 -64.422 54.438 1.00158.20 C +ATOM 4946 O THR C 150 13.329 -64.970 55.317 1.00128.36 O +ATOM 4947 CB THR C 150 10.157 -64.611 54.490 1.00137.70 C +ATOM 4948 OG1 THR C 150 10.150 -64.958 55.874 1.00153.91 O +ATOM 4949 CG2 THR C 150 8.935 -65.196 53.816 1.00130.72 C +ATOM 4950 N GLN C 151 12.939 -63.214 53.966 1.00166.39 N +ATOM 4951 CA GLN C 151 13.891 -62.337 54.643 1.00185.48 C +ATOM 4952 C GLN C 151 13.335 -60.904 54.634 1.00190.00 C +ATOM 4953 O GLN C 151 12.568 -60.512 53.753 1.00162.75 O +ATOM 4954 CB GLN C 151 15.328 -62.442 54.077 1.00183.51 C +ATOM 4955 CG GLN C 151 15.514 -61.840 52.707 1.00200.69 C +ATOM 4956 CD GLN C 151 16.975 -61.519 52.406 1.00204.36 C +ATOM 4957 OE1 GLN C 151 17.858 -62.298 52.724 1.00177.72 O +ATOM 4958 NE2 GLN C 151 17.228 -60.383 51.750 1.00219.93 N +ATOM 4959 N TYR C 152 13.619 -60.160 55.693 1.00197.39 N +ATOM 4960 CA TYR C 152 13.155 -58.779 55.780 1.00166.17 C +ATOM 4961 C TYR C 152 14.242 -57.855 56.285 1.00154.51 C +ATOM 4962 O TYR C 152 15.061 -58.270 57.104 1.00149.94 O +ATOM 4963 CB TYR C 152 11.901 -58.677 56.653 1.00140.27 C +ATOM 4964 CG TYR C 152 12.087 -58.090 58.041 1.00108.15 C +ATOM 4965 CD1 TYR C 152 12.860 -58.734 58.999 1.00 97.45 C +ATOM 4966 CD2 TYR C 152 11.378 -56.966 58.428 1.00113.07 C +ATOM 4967 CE1 TYR C 152 12.979 -58.234 60.288 1.00 96.30 C +ATOM 4968 CE2 TYR C 152 11.444 -56.482 59.725 1.00114.73 C +ATOM 4969 CZ TYR C 152 12.244 -57.119 60.651 1.00108.50 C +ATOM 4970 OH TYR C 152 12.306 -56.640 61.936 1.00 96.93 O +ATOM 4971 N GLN C 153 14.245 -56.622 55.782 1.00129.51 N +ATOM 4972 CA GLN C 153 15.095 -55.568 56.345 1.00128.52 C +ATOM 4973 C GLN C 153 14.247 -54.324 56.533 1.00109.84 C +ATOM 4974 O GLN C 153 13.282 -54.096 55.794 1.00 92.81 O +ATOM 4975 CB GLN C 153 16.303 -55.285 55.414 1.00133.86 C +ATOM 4976 CG GLN C 153 16.165 -54.052 54.501 1.00126.68 C +ATOM 4977 CD GLN C 153 17.371 -53.804 53.590 1.00 95.48 C +ATOM 4978 OE1 GLN C 153 18.157 -54.708 53.429 1.00113.23 O +ATOM 4979 NE2 GLN C 153 17.369 -52.701 52.815 1.00 68.82 N +ATOM 4980 N LEU C 154 14.656 -53.478 57.472 1.00102.54 N +ATOM 4981 CA LEU C 154 14.057 -52.156 57.573 1.00116.89 C +ATOM 4982 C LEU C 154 15.051 -51.060 57.946 1.00104.09 C +ATOM 4983 O LEU C 154 15.970 -51.276 58.765 1.00114.80 O +ATOM 4984 CB LEU C 154 12.887 -52.183 58.555 1.00117.66 C +ATOM 4985 CG LEU C 154 13.250 -52.319 60.034 1.00134.50 C +ATOM 4986 CD1 LEU C 154 13.331 -50.962 60.722 1.00121.23 C +ATOM 4987 CD2 LEU C 154 12.241 -53.231 60.718 1.00161.11 C +ATOM 4988 N ASP C 155 14.760 -49.866 57.416 1.00 76.55 N +ATOM 4989 CA ASP C 155 15.637 -48.708 57.465 1.00 79.46 C +ATOM 4990 C ASP C 155 14.908 -47.546 58.131 1.00 82.71 C +ATOM 4991 O ASP C 155 13.696 -47.578 58.264 1.00 82.71 O +ATOM 4992 CB ASP C 155 16.023 -48.302 56.055 1.00 78.19 C +ATOM 4993 CG ASP C 155 16.453 -49.488 55.215 1.00 89.81 C +ATOM 4994 OD1 ASP C 155 15.573 -50.199 54.693 1.00 80.93 O +ATOM 4995 OD2 ASP C 155 17.681 -49.679 55.021 1.00112.43 O +ATOM 4996 N GLN C 156 15.658 -46.550 58.603 1.00 93.33 N +ATOM 4997 CA GLN C 156 15.056 -45.408 59.296 1.00 92.15 C +ATOM 4998 C GLN C 156 15.305 -44.109 58.527 1.00 98.19 C +ATOM 4999 O GLN C 156 16.241 -44.014 57.754 1.00 79.67 O +ATOM 5000 CB GLN C 156 15.595 -45.292 60.723 1.00 93.23 C +ATOM 5001 CG GLN C 156 14.836 -44.311 61.596 1.00 90.20 C +ATOM 5002 CD GLN C 156 15.064 -44.556 63.080 1.00103.32 C +ATOM 5003 OE1 GLN C 156 15.931 -45.351 63.482 1.00 85.52 O +ATOM 5004 NE2 GLN C 156 14.294 -43.854 63.911 1.00112.01 N +ATOM 5005 N ILE C 157 14.433 -43.129 58.735 1.00101.52 N +ATOM 5006 CA ILE C 157 14.579 -41.812 58.123 1.00 79.62 C +ATOM 5007 C ILE C 157 13.902 -40.777 59.023 1.00 67.11 C +ATOM 5008 O ILE C 157 12.878 -41.066 59.664 1.00 65.91 O +ATOM 5009 CB ILE C 157 13.955 -41.785 56.726 1.00 73.00 C +ATOM 5010 CG1 ILE C 157 14.578 -40.692 55.886 1.00 64.83 C +ATOM 5011 CG2 ILE C 157 12.441 -41.578 56.826 1.00 86.85 C +ATOM 5012 CD1 ILE C 157 14.138 -40.708 54.434 1.00 78.95 C +ATOM 5013 N ALA C 158 14.548 -39.643 59.215 1.00 64.12 N +ATOM 5014 CA ALA C 158 14.036 -38.677 60.165 1.00 71.77 C +ATOM 5015 C ALA C 158 14.089 -37.332 59.548 1.00 73.61 C +ATOM 5016 O ALA C 158 14.947 -37.043 58.710 1.00131.44 O +ATOM 5017 CB ALA C 158 14.801 -38.710 61.500 1.00 81.11 C +ATOM 5018 N VAL C 159 13.169 -36.490 59.971 1.00 79.68 N +ATOM 5019 CA VAL C 159 13.041 -35.169 59.400 1.00122.01 C +ATOM 5020 C VAL C 159 12.828 -34.132 60.498 1.00152.28 C +ATOM 5021 O VAL C 159 11.949 -34.270 61.347 1.00205.52 O +ATOM 5022 CB VAL C 159 11.892 -35.134 58.372 1.00109.65 C +ATOM 5023 CG1 VAL C 159 11.418 -33.713 58.118 1.00 95.46 C +ATOM 5024 CG2 VAL C 159 12.339 -35.776 57.069 1.00120.35 C +ATOM 5025 N ASN C 160 13.630 -33.073 60.453 1.00138.97 N +ATOM 5026 CA ASN C 160 13.386 -31.883 61.243 1.00120.33 C +ATOM 5027 C ASN C 160 12.609 -30.872 60.386 1.00 90.06 C +ATOM 5028 O ASN C 160 12.997 -30.579 59.257 1.00 84.56 O +ATOM 5029 CB ASN C 160 14.728 -31.305 61.702 1.00123.86 C +ATOM 5030 CG ASN C 160 14.596 -30.004 62.499 1.00135.35 C +ATOM 5031 OD1 ASN C 160 13.906 -29.061 62.103 1.00 92.98 O +ATOM 5032 ND2 ASN C 160 15.346 -29.918 63.587 1.00151.53 N +ATOM 5033 N LEU C 161 11.508 -30.347 60.931 1.00 77.83 N +ATOM 5034 CA LEU C 161 10.902 -29.091 60.448 1.00 71.51 C +ATOM 5035 C LEU C 161 10.761 -28.072 61.556 1.00 65.24 C +ATOM 5036 O LEU C 161 10.660 -28.420 62.728 1.00104.82 O +ATOM 5037 CB LEU C 161 9.529 -29.345 59.900 1.00 62.58 C +ATOM 5038 CG LEU C 161 9.477 -30.252 58.686 1.00 86.76 C +ATOM 5039 CD1 LEU C 161 8.034 -30.584 58.363 1.00 84.65 C +ATOM 5040 CD2 LEU C 161 10.170 -29.581 57.502 1.00104.79 C +ATOM 5041 N ARG C 162 10.942 -26.812 61.230 1.00 67.21 N +ATOM 5042 CA ARG C 162 10.931 -25.802 62.278 1.00 79.02 C +ATOM 5043 C ARG C 162 10.467 -24.435 61.785 1.00 96.77 C +ATOM 5044 O ARG C 162 10.952 -23.917 60.776 1.00120.33 O +ATOM 5045 CB ARG C 162 12.284 -25.709 63.020 1.00 77.79 C +ATOM 5046 CG ARG C 162 13.488 -25.274 62.205 1.00104.09 C +ATOM 5047 CD ARG C 162 14.610 -24.831 63.132 1.00131.39 C +ATOM 5048 NE ARG C 162 15.737 -24.215 62.423 1.00153.33 N +ATOM 5049 CZ ARG C 162 16.722 -24.880 61.829 1.00133.24 C +ATOM 5050 NH1 ARG C 162 16.689 -26.201 61.751 1.00115.05 N +ATOM 5051 NH2 ARG C 162 17.729 -24.206 61.285 1.00137.78 N +ATOM 5052 N VAL C 163 9.537 -23.852 62.541 1.00114.70 N +ATOM 5053 CA VAL C 163 8.969 -22.530 62.250 1.00127.21 C +ATOM 5054 C VAL C 163 9.826 -21.449 62.862 1.00128.67 C +ATOM 5055 O VAL C 163 10.010 -21.425 64.080 1.00191.42 O +ATOM 5056 CB VAL C 163 7.566 -22.349 62.859 1.00108.65 C +ATOM 5057 CG1 VAL C 163 7.047 -20.945 62.544 1.00 81.89 C +ATOM 5058 CG2 VAL C 163 6.628 -23.449 62.364 1.00116.00 C +ATOM 5059 N VAL C 164 10.293 -20.537 62.017 1.00 90.28 N +ATOM 5060 CA VAL C 164 11.134 -19.421 62.445 1.00 62.18 C +ATOM 5061 C VAL C 164 10.394 -18.137 62.230 1.00 61.64 C +ATOM 5062 O VAL C 164 9.717 -17.971 61.184 1.00 90.66 O +ATOM 5063 CB VAL C 164 12.408 -19.333 61.622 1.00 56.52 C +ATOM 5064 CG1 VAL C 164 13.218 -18.134 62.041 1.00 53.04 C +ATOM 5065 CG2 VAL C 164 13.208 -20.595 61.780 1.00 58.07 C +ATOM 5066 N ASN C 165 10.459 -17.263 63.227 1.00 48.84 N +ATOM 5067 CA ASN C 165 9.725 -16.021 63.137 1.00 67.05 C +ATOM 5068 C ASN C 165 10.557 -14.991 62.430 1.00 79.49 C +ATOM 5069 O ASN C 165 11.657 -14.655 62.908 1.00109.77 O +ATOM 5070 CB ASN C 165 9.345 -15.499 64.509 1.00 76.12 C +ATOM 5071 CG ASN C 165 8.434 -14.274 64.420 1.00 98.62 C +ATOM 5072 OD1 ASN C 165 7.925 -13.927 63.350 1.00 51.42 O +ATOM 5073 ND2 ASN C 165 8.255 -13.595 65.544 1.00125.55 N +ATOM 5074 N VAL C 166 10.050 -14.478 61.302 1.00 86.71 N +ATOM 5075 CA VAL C 166 10.808 -13.533 60.465 1.00106.07 C +ATOM 5076 C VAL C 166 11.112 -12.253 61.226 1.00107.58 C +ATOM 5077 O VAL C 166 12.219 -11.736 61.149 1.00 85.03 O +ATOM 5078 CB VAL C 166 10.034 -13.166 59.191 1.00100.73 C +ATOM 5079 CG1 VAL C 166 10.458 -11.798 58.642 1.00 80.19 C +ATOM 5080 CG2 VAL C 166 10.187 -14.282 58.161 1.00114.79 C +ATOM 5081 N SER C 167 10.158 -11.840 62.053 1.00105.72 N +ATOM 5082 CA SER C 167 10.249 -10.576 62.750 1.00106.53 C +ATOM 5083 C SER C 167 11.282 -10.571 63.886 1.00112.39 C +ATOM 5084 O SER C 167 11.656 -9.504 64.365 1.00 95.40 O +ATOM 5085 CB SER C 167 8.876 -10.202 63.283 1.00128.89 C +ATOM 5086 OG SER C 167 7.878 -10.424 62.294 1.00179.01 O +ATOM 5087 N THR C 168 11.786 -11.748 64.275 1.00123.95 N +ATOM 5088 CA THR C 168 12.752 -11.850 65.380 1.00104.91 C +ATOM 5089 C THR C 168 13.917 -12.817 65.135 1.00 74.51 C +ATOM 5090 O THR C 168 15.017 -12.644 65.651 1.00 68.25 O +ATOM 5091 CB THR C 168 12.040 -12.271 66.678 1.00127.51 C +ATOM 5092 OG1 THR C 168 11.259 -13.452 66.442 1.00122.48 O +ATOM 5093 CG2 THR C 168 11.131 -11.142 67.191 1.00141.74 C +ATOM 5094 N GLY C 169 13.646 -13.894 64.434 1.00 65.91 N +ATOM 5095 CA GLY C 169 14.614 -14.952 64.353 1.00 84.97 C +ATOM 5096 C GLY C 169 14.418 -16.005 65.425 1.00109.74 C +ATOM 5097 O GLY C 169 15.023 -17.084 65.363 1.00125.47 O +ATOM 5098 N GLU C 170 13.546 -15.731 66.394 1.00115.57 N +ATOM 5099 CA GLU C 170 13.112 -16.766 67.335 1.00137.67 C +ATOM 5100 C GLU C 170 12.562 -17.936 66.539 1.00130.08 C +ATOM 5101 O GLU C 170 11.718 -17.765 65.677 1.00106.90 O +ATOM 5102 CB GLU C 170 12.019 -16.252 68.300 1.00158.40 C +ATOM 5103 CG GLU C 170 12.541 -15.374 69.435 1.00167.95 C +ATOM 5104 CD GLU C 170 11.613 -14.231 69.820 1.00163.30 C +ATOM 5105 OE1 GLU C 170 10.646 -13.962 69.071 1.00149.55 O +ATOM 5106 OE2 GLU C 170 11.906 -13.536 70.822 1.00150.53 O +ATOM 5107 N ILE C 171 13.056 -19.135 66.815 1.00116.56 N +ATOM 5108 CA ILE C 171 12.367 -20.331 66.358 1.00129.16 C +ATOM 5109 C ILE C 171 11.081 -20.517 67.167 1.00132.94 C +ATOM 5110 O ILE C 171 11.128 -20.497 68.389 1.00189.36 O +ATOM 5111 CB ILE C 171 13.259 -21.562 66.511 1.00119.03 C +ATOM 5112 CG1 ILE C 171 14.401 -21.476 65.503 1.00143.67 C +ATOM 5113 CG2 ILE C 171 12.433 -22.824 66.312 1.00126.02 C +ATOM 5114 CD1 ILE C 171 15.538 -22.419 65.808 1.00159.70 C +ATOM 5115 N LEU C 172 9.939 -20.614 66.493 1.00124.32 N +ATOM 5116 CA LEU C 172 8.657 -20.684 67.189 1.00105.31 C +ATOM 5117 C LEU C 172 8.218 -22.130 67.406 1.00121.73 C +ATOM 5118 O LEU C 172 7.273 -22.416 68.174 1.00150.75 O +ATOM 5119 CB LEU C 172 7.556 -19.915 66.440 1.00 83.13 C +ATOM 5120 CG LEU C 172 7.327 -18.420 66.728 1.00 78.75 C +ATOM 5121 CD1 LEU C 172 8.621 -17.820 67.233 1.00 74.75 C +ATOM 5122 CD2 LEU C 172 6.688 -17.579 65.631 1.00 72.02 C +ATOM 5123 N SER C 173 8.903 -23.046 66.736 1.00108.46 N +ATOM 5124 CA SER C 173 8.602 -24.452 66.881 1.00129.73 C +ATOM 5125 C SER C 173 9.659 -25.293 66.185 1.00130.72 C +ATOM 5126 O SER C 173 9.942 -25.097 65.012 1.00146.87 O +ATOM 5127 CB SER C 173 7.219 -24.768 66.280 1.00164.31 C +ATOM 5128 OG SER C 173 7.041 -26.169 66.094 1.00208.19 O +ATOM 5129 N SER C 174 10.138 -26.328 66.866 1.00155.60 N +ATOM 5130 CA SER C 174 10.930 -27.392 66.219 1.00155.29 C +ATOM 5131 C SER C 174 10.295 -28.758 66.449 1.00144.46 C +ATOM 5132 O SER C 174 9.809 -29.051 67.539 1.00167.48 O +ATOM 5133 CB SER C 174 12.357 -27.418 66.771 1.00155.48 C +ATOM 5134 OG SER C 174 13.214 -28.251 66.006 1.00134.48 O +ATOM 5135 N VAL C 175 10.242 -29.565 65.395 1.00138.36 N +ATOM 5136 CA VAL C 175 9.653 -30.901 65.472 1.00131.39 C +ATOM 5137 C VAL C 175 10.528 -31.921 64.767 1.00135.90 C +ATOM 5138 O VAL C 175 11.105 -31.633 63.707 1.00250.99 O +ATOM 5139 CB VAL C 175 8.218 -30.948 64.877 1.00118.05 C +ATOM 5140 CG1 VAL C 175 7.284 -30.059 65.676 1.00129.59 C +ATOM 5141 CG2 VAL C 175 8.196 -30.509 63.429 1.00124.23 C +ATOM 5142 N ASN C 176 10.557 -33.129 65.312 1.00113.58 N +ATOM 5143 CA ASN C 176 11.441 -34.177 64.824 1.00133.03 C +ATOM 5144 C ASN C 176 10.665 -35.452 64.511 1.00116.77 C +ATOM 5145 O ASN C 176 10.509 -36.298 65.397 1.00188.97 O +ATOM 5146 CB ASN C 176 12.511 -34.448 65.898 1.00146.61 C +ATOM 5147 CG ASN C 176 13.841 -33.758 65.615 1.00141.12 C +ATOM 5148 OD1 ASN C 176 14.882 -33.995 66.296 1.00130.52 O +ATOM 5149 ND2 ASN C 176 13.799 -32.840 64.665 1.00125.33 N +ATOM 5150 N THR C 177 10.269 -35.650 63.252 1.00 83.78 N +ATOM 5151 CA THR C 177 9.534 -36.862 62.867 1.00 86.21 C +ATOM 5152 C THR C 177 10.436 -37.969 62.310 1.00 79.25 C +ATOM 5153 O THR C 177 11.561 -37.714 61.896 1.00 96.67 O +ATOM 5154 CB THR C 177 8.439 -36.556 61.841 1.00 85.72 C +ATOM 5155 OG1 THR C 177 9.040 -36.239 60.591 1.00103.65 O +ATOM 5156 CG2 THR C 177 7.586 -35.381 62.305 1.00 86.69 C +ATOM 5157 N SER C 178 9.942 -39.202 62.342 1.00 73.93 N +ATOM 5158 CA SER C 178 10.724 -40.367 61.927 1.00 85.30 C +ATOM 5159 C SER C 178 9.830 -41.419 61.273 1.00 98.75 C +ATOM 5160 O SER C 178 8.633 -41.522 61.572 1.00116.22 O +ATOM 5161 CB SER C 178 11.465 -40.995 63.108 1.00 77.07 C +ATOM 5162 OG SER C 178 11.956 -42.298 62.778 1.00 98.83 O +ATOM 5163 N LYS C 179 10.422 -42.232 60.405 1.00 89.98 N +ATOM 5164 CA LYS C 179 9.638 -43.183 59.645 1.00 99.12 C +ATOM 5165 C LYS C 179 10.505 -44.353 59.202 1.00102.38 C +ATOM 5166 O LYS C 179 11.692 -44.206 58.913 1.00 94.69 O +ATOM 5167 CB LYS C 179 9.013 -42.480 58.444 1.00106.10 C +ATOM 5168 CG LYS C 179 7.621 -42.963 58.072 1.00114.55 C +ATOM 5169 CD LYS C 179 7.682 -44.060 57.025 1.00138.87 C +ATOM 5170 CE LYS C 179 6.279 -44.727 57.043 1.00155.89 C +ATOM 5171 NZ LYS C 179 5.413 -44.073 56.030 1.00172.03 N +ATOM 5172 N THR C 180 9.892 -45.528 59.167 1.00129.63 N +ATOM 5173 CA THR C 180 10.617 -46.754 58.882 1.00148.75 C +ATOM 5174 C THR C 180 10.279 -47.267 57.479 1.00153.35 C +ATOM 5175 O THR C 180 9.111 -47.340 57.088 1.00134.23 O +ATOM 5176 CB THR C 180 10.353 -47.850 59.948 1.00145.91 C +ATOM 5177 OG1 THR C 180 10.596 -49.140 59.381 1.00150.84 O +ATOM 5178 CG2 THR C 180 8.925 -47.770 60.481 1.00118.27 C +ATOM 5179 N ILE C 181 11.320 -47.613 56.727 1.00162.45 N +ATOM 5180 CA ILE C 181 11.153 -48.161 55.384 1.00161.99 C +ATOM 5181 C ILE C 181 11.255 -49.689 55.421 1.00127.65 C +ATOM 5182 O ILE C 181 12.323 -50.241 55.737 1.00135.86 O +ATOM 5183 CB ILE C 181 12.201 -47.565 54.404 1.00163.63 C +ATOM 5184 CG1 ILE C 181 12.176 -46.036 54.469 1.00165.64 C +ATOM 5185 CG2 ILE C 181 11.940 -48.003 52.966 1.00160.94 C +ATOM 5186 CD1 ILE C 181 13.485 -45.423 54.910 1.00153.05 C +ATOM 5187 N LEU C 182 10.156 -50.356 55.073 1.00 84.55 N +ATOM 5188 CA LEU C 182 10.110 -51.821 55.045 1.00111.55 C +ATOM 5189 C LEU C 182 10.498 -52.491 53.706 1.00122.18 C +ATOM 5190 O LEU C 182 10.082 -52.052 52.630 1.00122.05 O +ATOM 5191 CB LEU C 182 8.709 -52.281 55.418 1.00108.50 C +ATOM 5192 CG LEU C 182 8.487 -53.801 55.465 1.00 98.24 C +ATOM 5193 CD1 LEU C 182 9.359 -54.506 56.499 1.00 90.78 C +ATOM 5194 CD2 LEU C 182 7.011 -54.042 55.729 1.00 96.58 C +ATOM 5195 N SER C 183 11.230 -53.601 53.804 1.00130.36 N +ATOM 5196 CA SER C 183 11.560 -54.429 52.649 1.00140.31 C +ATOM 5197 C SER C 183 11.476 -55.912 53.022 1.00152.94 C +ATOM 5198 O SER C 183 11.874 -56.304 54.122 1.00153.94 O +ATOM 5199 CB SER C 183 12.974 -54.105 52.155 1.00154.08 C +ATOM 5200 OG SER C 183 13.249 -52.720 52.252 1.00149.32 O +ATOM 5201 N TYR C 184 10.965 -56.735 52.109 1.00157.29 N +ATOM 5202 CA TYR C 184 10.921 -58.186 52.328 1.00130.47 C +ATOM 5203 C TYR C 184 10.977 -59.018 51.044 1.00132.90 C +ATOM 5204 O TYR C 184 10.573 -58.571 49.957 1.00144.85 O +ATOM 5205 CB TYR C 184 9.706 -58.578 53.175 1.00104.83 C +ATOM 5206 CG TYR C 184 8.376 -58.187 52.588 1.00117.30 C +ATOM 5207 CD1 TYR C 184 7.719 -59.017 51.689 1.00149.45 C +ATOM 5208 CD2 TYR C 184 7.751 -57.001 52.953 1.00113.33 C +ATOM 5209 CE1 TYR C 184 6.496 -58.656 51.146 1.00147.98 C +ATOM 5210 CE2 TYR C 184 6.520 -56.637 52.421 1.00111.44 C +ATOM 5211 CZ TYR C 184 5.901 -57.460 51.514 1.00118.51 C +ATOM 5212 OH TYR C 184 4.696 -57.087 50.975 1.00100.17 O +ATOM 5213 N GLU C 185 11.460 -60.247 51.204 1.00148.47 N +ATOM 5214 CA GLU C 185 11.645 -61.191 50.100 1.00166.66 C +ATOM 5215 C GLU C 185 11.123 -62.566 50.472 1.00171.19 C +ATOM 5216 O GLU C 185 11.684 -63.238 51.331 1.00192.82 O +ATOM 5217 CB GLU C 185 13.110 -61.341 49.686 1.00177.25 C +ATOM 5218 CG GLU C 185 13.917 -60.060 49.626 1.00196.81 C +ATOM 5219 CD GLU C 185 15.276 -60.298 48.987 1.00219.12 C +ATOM 5220 OE1 GLU C 185 15.605 -61.475 48.688 1.00238.59 O +ATOM 5221 OE2 GLU C 185 16.037 -59.324 48.842 1.00210.59 O +ATOM 5222 N VAL C 186 10.053 -62.976 49.802 1.00172.50 N +ATOM 5223 CA VAL C 186 9.460 -64.291 49.986 1.00147.44 C +ATOM 5224 C VAL C 186 9.854 -65.205 48.822 1.00148.19 C +ATOM 5225 O VAL C 186 9.880 -64.773 47.674 1.00127.04 O +ATOM 5226 CB VAL C 186 7.923 -64.190 50.080 1.00116.92 C +ATOM 5227 CG1 VAL C 186 7.338 -65.535 50.471 1.00116.72 C +ATOM 5228 CG2 VAL C 186 7.510 -63.112 51.075 1.00 97.14 C +ATOM 5229 N GLN C 187 10.170 -66.459 49.134 1.00151.21 N +ATOM 5230 CA GLN C 187 10.653 -67.392 48.126 1.00155.74 C +ATOM 5231 C GLN C 187 10.251 -68.813 48.456 1.00144.63 C +ATOM 5232 O GLN C 187 10.353 -69.239 49.603 1.00124.95 O +ATOM 5233 CB GLN C 187 12.183 -67.325 48.040 1.00171.90 C +ATOM 5234 CG GLN C 187 12.745 -66.243 47.136 1.00185.43 C +ATOM 5235 CD GLN C 187 14.186 -65.904 47.476 1.00205.56 C +ATOM 5236 OE1 GLN C 187 14.980 -66.795 47.790 1.00232.80 O +ATOM 5237 NE2 GLN C 187 14.533 -64.614 47.423 1.00204.42 N +ATOM 5238 N ALA C 188 9.832 -69.551 47.435 1.00165.19 N +ATOM 5239 CA ALA C 188 9.489 -70.961 47.612 1.00166.13 C +ATOM 5240 C ALA C 188 9.929 -71.779 46.404 1.00169.92 C +ATOM 5241 O ALA C 188 9.839 -71.312 45.275 1.00174.73 O +ATOM 5242 CB ALA C 188 7.994 -71.112 47.844 1.00145.24 C +ATOM 5243 N GLY C 189 10.457 -72.974 46.649 1.00179.58 N +ATOM 5244 CA GLY C 189 10.982 -73.815 45.579 1.00202.65 C +ATOM 5245 C GLY C 189 10.764 -75.292 45.824 1.00205.82 C +ATOM 5246 O GLY C 189 10.918 -75.768 46.949 1.00226.46 O +ATOM 5247 N VAL C 190 10.379 -76.011 44.775 1.00196.35 N +ATOM 5248 CA VAL C 190 10.163 -77.449 44.861 1.00192.11 C +ATOM 5249 C VAL C 190 11.187 -78.176 43.985 1.00201.67 C +ATOM 5250 O VAL C 190 11.444 -77.770 42.849 1.00178.28 O +ATOM 5251 CB VAL C 190 8.731 -77.828 44.426 1.00182.28 C +ATOM 5252 CG1 VAL C 190 8.443 -79.280 44.763 1.00188.84 C +ATOM 5253 CG2 VAL C 190 7.705 -76.906 45.081 1.00173.06 C +ATOM 5254 N PHE C 191 11.777 -79.246 44.519 1.00214.44 N +ATOM 5255 CA PHE C 191 12.904 -79.920 43.860 1.00193.13 C +ATOM 5256 C PHE C 191 12.720 -81.441 43.861 1.00147.77 C +ATOM 5257 O PHE C 191 12.384 -82.018 44.893 1.00 87.17 O +ATOM 5258 CB PHE C 191 14.219 -79.547 44.562 1.00178.35 C +ATOM 5259 CG PHE C 191 15.445 -79.751 43.713 1.00173.39 C +ATOM 5260 CD1 PHE C 191 15.902 -81.029 43.418 1.00148.92 C +ATOM 5261 CD2 PHE C 191 16.148 -78.663 43.215 1.00195.57 C +ATOM 5262 CE1 PHE C 191 17.034 -81.221 42.642 1.00140.91 C +ATOM 5263 CE2 PHE C 191 17.278 -78.848 42.431 1.00197.98 C +ATOM 5264 CZ PHE C 191 17.727 -80.129 42.153 1.00166.95 C +ATOM 5265 N LEU C 200 12.728 -82.656 38.320 1.00108.11 N +ATOM 5266 CA LEU C 200 11.744 -81.604 38.550 1.00131.94 C +ATOM 5267 C LEU C 200 12.289 -80.530 39.482 1.00177.44 C +ATOM 5268 O LEU C 200 12.527 -80.794 40.666 1.00215.67 O +ATOM 5269 CB LEU C 200 10.457 -82.171 39.158 1.00108.84 C +ATOM 5270 CG LEU C 200 9.458 -81.098 39.626 1.00111.13 C +ATOM 5271 CD1 LEU C 200 8.350 -80.926 38.598 1.00109.00 C +ATOM 5272 CD2 LEU C 200 8.888 -81.369 41.015 1.00 98.55 C +ATOM 5273 N GLU C 201 12.460 -79.317 38.950 1.00184.02 N +ATOM 5274 CA GLU C 201 12.610 -78.120 39.781 1.00147.63 C +ATOM 5275 C GLU C 201 11.522 -77.109 39.465 1.00140.86 C +ATOM 5276 O GLU C 201 11.061 -77.029 38.327 1.00165.02 O +ATOM 5277 CB GLU C 201 13.980 -77.487 39.567 1.00148.53 C +ATOM 5278 CG GLU C 201 14.387 -76.563 40.702 1.00162.55 C +ATOM 5279 CD GLU C 201 15.762 -75.943 40.490 1.00188.93 C +ATOM 5280 OE1 GLU C 201 16.732 -76.683 40.231 1.00222.23 O +ATOM 5281 OE2 GLU C 201 15.895 -74.718 40.632 1.00181.16 O +ATOM 5282 N GLY C 202 11.110 -76.343 40.470 1.00142.44 N +ATOM 5283 CA GLY C 202 10.164 -75.243 40.278 1.00155.81 C +ATOM 5284 C GLY C 202 10.301 -74.185 41.365 1.00152.27 C +ATOM 5285 O GLY C 202 10.267 -74.508 42.544 1.00138.44 O +ATOM 5286 N GLU C 203 10.449 -72.921 40.970 1.00148.30 N +ATOM 5287 CA GLU C 203 10.645 -71.826 41.929 1.00128.80 C +ATOM 5288 C GLU C 203 9.696 -70.645 41.717 1.00117.12 C +ATOM 5289 O GLU C 203 9.441 -70.219 40.588 1.00115.07 O +ATOM 5290 CB GLU C 203 12.095 -71.321 41.884 1.00129.79 C +ATOM 5291 CG GLU C 203 13.110 -72.374 42.325 1.00139.53 C +ATOM 5292 CD GLU C 203 13.446 -72.401 43.816 1.00146.38 C +ATOM 5293 OE1 GLU C 203 13.578 -71.351 44.463 1.00146.43 O +ATOM 5294 OE2 GLU C 203 13.633 -73.503 44.361 1.00164.87 O +ATOM 5295 N VAL C 204 9.186 -70.125 42.828 1.00109.48 N +ATOM 5296 CA VAL C 204 8.449 -68.864 42.854 1.00115.13 C +ATOM 5297 C VAL C 204 9.145 -67.921 43.828 1.00106.12 C +ATOM 5298 O VAL C 204 9.536 -68.322 44.926 1.00113.80 O +ATOM 5299 CB VAL C 204 6.964 -69.076 43.270 1.00118.50 C +ATOM 5300 CG1 VAL C 204 6.286 -67.766 43.682 1.00 95.51 C +ATOM 5301 CG2 VAL C 204 6.195 -69.744 42.134 1.00109.98 C +ATOM 5302 N GLY C 205 9.288 -66.671 43.415 1.00115.47 N +ATOM 5303 CA GLY C 205 9.849 -65.638 44.271 1.00130.57 C +ATOM 5304 C GLY C 205 9.087 -64.322 44.184 1.00128.69 C +ATOM 5305 O GLY C 205 8.489 -64.002 43.152 1.00105.22 O +ATOM 5306 N TYR C 206 9.104 -63.561 45.275 1.00117.62 N +ATOM 5307 CA TYR C 206 8.496 -62.232 45.309 1.00109.64 C +ATOM 5308 C TYR C 206 9.276 -61.330 46.252 1.00123.48 C +ATOM 5309 O TYR C 206 9.707 -61.765 47.310 1.00160.97 O +ATOM 5310 CB TYR C 206 7.033 -62.308 45.767 1.00 95.73 C +ATOM 5311 CG TYR C 206 6.367 -60.964 45.889 1.00100.80 C +ATOM 5312 CD1 TYR C 206 5.967 -60.257 44.747 1.00110.83 C +ATOM 5313 CD2 TYR C 206 6.164 -60.373 47.132 1.00 88.78 C +ATOM 5314 CE1 TYR C 206 5.392 -58.998 44.845 1.00114.58 C +ATOM 5315 CE2 TYR C 206 5.590 -59.115 47.238 1.00108.89 C +ATOM 5316 CZ TYR C 206 5.214 -58.427 46.098 1.00122.86 C +ATOM 5317 OH TYR C 206 4.619 -57.183 46.209 1.00149.39 O +ATOM 5318 N THR C 207 9.447 -60.064 45.877 1.00113.90 N +ATOM 5319 CA THR C 207 10.132 -59.097 46.736 1.00 92.25 C +ATOM 5320 C THR C 207 9.372 -57.768 46.742 1.00 67.37 C +ATOM 5321 O THR C 207 8.957 -57.274 45.692 1.00 44.99 O +ATOM 5322 CB THR C 207 11.594 -58.876 46.284 1.00110.95 C +ATOM 5323 OG1 THR C 207 11.611 -58.345 44.956 1.00137.36 O +ATOM 5324 CG2 THR C 207 12.373 -60.174 46.300 1.00107.83 C +ATOM 5325 N SER C 208 9.266 -57.156 47.916 1.00 70.30 N +ATOM 5326 CA SER C 208 8.667 -55.824 48.020 1.00 91.52 C +ATOM 5327 C SER C 208 9.507 -54.825 48.865 1.00122.87 C +ATOM 5328 O SER C 208 9.826 -55.094 50.014 1.00112.78 O +ATOM 5329 CB SER C 208 7.256 -55.933 48.584 1.00 74.76 C +ATOM 5330 OG SER C 208 6.692 -54.651 48.798 1.00 78.08 O +ATOM 5331 N ASN C 209 9.810 -53.664 48.276 1.00132.77 N +ATOM 5332 CA ASN C 209 10.430 -52.545 48.973 1.00110.12 C +ATOM 5333 C ASN C 209 9.470 -51.376 49.073 1.00114.67 C +ATOM 5334 O ASN C 209 8.821 -50.998 48.090 1.00 98.14 O +ATOM 5335 CB ASN C 209 11.659 -52.061 48.219 1.00111.81 C +ATOM 5336 CG ASN C 209 12.785 -53.039 48.279 1.00127.51 C +ATOM 5337 OD1 ASN C 209 13.552 -53.071 49.243 1.00126.18 O +ATOM 5338 ND2 ASN C 209 12.914 -53.834 47.228 1.00149.48 N +ATOM 5339 N GLU C 210 9.446 -50.737 50.237 1.00129.27 N +ATOM 5340 CA GLU C 210 8.799 -49.428 50.358 1.00129.41 C +ATOM 5341 C GLU C 210 9.624 -48.374 49.600 1.00150.69 C +ATOM 5342 O GLU C 210 10.854 -48.432 49.593 1.00155.24 O +ATOM 5343 CB GLU C 210 8.673 -49.030 51.829 1.00119.47 C +ATOM 5344 CG GLU C 210 7.325 -48.458 52.231 1.00 96.61 C +ATOM 5345 CD GLU C 210 7.137 -48.465 53.749 1.00 91.23 C +ATOM 5346 OE1 GLU C 210 7.726 -49.340 54.464 1.00 56.39 O +ATOM 5347 OE2 GLU C 210 6.338 -47.620 54.204 1.00 79.78 O +ATOM 5348 N PRO C 211 8.949 -47.438 48.909 1.00149.58 N +ATOM 5349 CA PRO C 211 9.681 -46.332 48.308 1.00129.97 C +ATOM 5350 C PRO C 211 10.158 -45.341 49.365 1.00 95.52 C +ATOM 5351 O PRO C 211 9.361 -44.864 50.191 1.00 73.39 O +ATOM 5352 CB PRO C 211 8.638 -45.685 47.379 1.00144.45 C +ATOM 5353 CG PRO C 211 7.581 -46.710 47.181 1.00118.47 C +ATOM 5354 CD PRO C 211 7.539 -47.446 48.486 1.00140.13 C +ATOM 5355 N VAL C 212 11.450 -45.068 49.359 1.00 75.05 N +ATOM 5356 CA VAL C 212 12.029 -44.134 50.322 1.00100.75 C +ATOM 5357 C VAL C 212 11.405 -42.775 50.063 1.00104.43 C +ATOM 5358 O VAL C 212 11.147 -41.988 50.984 1.00117.28 O +ATOM 5359 CB VAL C 212 13.582 -44.056 50.172 1.00118.60 C +ATOM 5360 CG1 VAL C 212 14.193 -43.155 51.251 1.00 90.95 C +ATOM 5361 CG2 VAL C 212 14.214 -45.455 50.218 1.00136.77 C +ATOM 5362 N MET C 213 11.304 -42.469 48.769 1.00108.03 N +ATOM 5363 CA MET C 213 10.560 -41.330 48.214 1.00 91.17 C +ATOM 5364 C MET C 213 9.245 -41.056 48.973 1.00109.98 C +ATOM 5365 O MET C 213 8.967 -39.937 49.435 1.00 84.93 O +ATOM 5366 CB MET C 213 10.294 -41.742 46.783 1.00 74.06 C +ATOM 5367 CG MET C 213 9.582 -40.767 45.915 1.00 86.15 C +ATOM 5368 SD MET C 213 9.432 -41.563 44.297 1.00105.36 S +ATOM 5369 CE MET C 213 7.635 -41.805 44.377 1.00134.54 C +ATOM 5370 N LEU C 214 8.500 -42.128 49.195 1.00125.75 N +ATOM 5371 CA LEU C 214 7.135 -42.028 49.664 1.00127.72 C +ATOM 5372 C LEU C 214 7.133 -41.910 51.192 1.00136.65 C +ATOM 5373 O LEU C 214 6.224 -41.322 51.787 1.00138.05 O +ATOM 5374 CB LEU C 214 6.350 -43.263 49.200 1.00135.46 C +ATOM 5375 CG LEU C 214 4.942 -43.071 48.644 1.00131.56 C +ATOM 5376 CD1 LEU C 214 4.913 -42.166 47.422 1.00 99.79 C +ATOM 5377 CD2 LEU C 214 4.338 -44.439 48.323 1.00135.35 C +ATOM 5378 N CYS C 215 8.142 -42.502 51.827 1.00128.02 N +ATOM 5379 CA CYS C 215 8.289 -42.428 53.283 1.00131.57 C +ATOM 5380 C CYS C 215 8.701 -41.023 53.702 1.00137.02 C +ATOM 5381 O CYS C 215 8.249 -40.488 54.728 1.00133.87 O +ATOM 5382 CB CYS C 215 9.349 -43.420 53.757 1.00112.50 C +ATOM 5383 SG CYS C 215 8.904 -45.134 53.500 1.00134.14 S +ATOM 5384 N LEU C 216 9.624 -40.459 52.929 1.00117.86 N +ATOM 5385 CA LEU C 216 10.033 -39.093 53.141 1.00 84.46 C +ATOM 5386 C LEU C 216 8.801 -38.216 53.095 1.00 79.98 C +ATOM 5387 O LEU C 216 8.590 -37.363 53.963 1.00 69.67 O +ATOM 5388 CB LEU C 216 11.054 -38.668 52.082 1.00 94.46 C +ATOM 5389 CG LEU C 216 11.541 -37.213 52.167 1.00106.13 C +ATOM 5390 CD1 LEU C 216 12.141 -36.883 53.524 1.00120.16 C +ATOM 5391 CD2 LEU C 216 12.556 -36.911 51.074 1.00 99.29 C +ATOM 5392 N MET C 217 7.984 -38.411 52.059 1.00102.97 N +ATOM 5393 CA MET C 217 6.818 -37.545 51.835 1.00126.78 C +ATOM 5394 C MET C 217 5.852 -37.667 53.010 1.00121.49 C +ATOM 5395 O MET C 217 5.413 -36.653 53.564 1.00117.33 O +ATOM 5396 CB MET C 217 6.112 -37.882 50.508 1.00120.65 C +ATOM 5397 CG MET C 217 5.686 -36.650 49.709 1.00103.06 C +ATOM 5398 SD MET C 217 4.353 -35.739 50.506 1.00 99.79 S +ATOM 5399 CE MET C 217 4.273 -34.239 49.528 1.00117.68 C +ATOM 5400 N SER C 218 5.601 -38.904 53.427 1.00107.95 N +ATOM 5401 CA SER C 218 4.730 -39.177 54.556 1.00119.70 C +ATOM 5402 C SER C 218 5.204 -38.437 55.811 1.00128.55 C +ATOM 5403 O SER C 218 4.412 -37.771 56.498 1.00112.20 O +ATOM 5404 CB SER C 218 4.680 -40.686 54.820 1.00116.39 C +ATOM 5405 OG SER C 218 3.659 -41.001 55.762 1.00162.67 O +ATOM 5406 N ALA C 219 6.491 -38.575 56.116 1.00136.58 N +ATOM 5407 CA ALA C 219 7.052 -38.036 57.359 1.00131.61 C +ATOM 5408 C ALA C 219 7.029 -36.505 57.381 1.00108.82 C +ATOM 5409 O ALA C 219 6.768 -35.880 58.410 1.00 98.40 O +ATOM 5410 CB ALA C 219 8.464 -38.545 57.537 1.00123.28 C +ATOM 5411 N ILE C 220 7.192 -35.905 56.215 1.00102.99 N +ATOM 5412 CA ILE C 220 7.092 -34.456 56.104 1.00104.38 C +ATOM 5413 C ILE C 220 5.667 -33.968 56.378 1.00110.77 C +ATOM 5414 O ILE C 220 5.464 -32.951 57.051 1.00 98.44 O +ATOM 5415 CB ILE C 220 7.579 -33.962 54.718 1.00112.40 C +ATOM 5416 CG1 ILE C 220 9.097 -34.183 54.598 1.00102.13 C +ATOM 5417 CG2 ILE C 220 7.232 -32.489 54.506 1.00104.09 C +ATOM 5418 CD1 ILE C 220 9.630 -34.116 53.187 1.00 91.55 C +ATOM 5419 N GLU C 221 4.674 -34.683 55.846 1.00135.96 N +ATOM 5420 CA GLU C 221 3.253 -34.349 56.092 1.00137.37 C +ATOM 5421 C GLU C 221 2.932 -34.382 57.588 1.00116.46 C +ATOM 5422 O GLU C 221 2.433 -33.404 58.153 1.00 79.34 O +ATOM 5423 CB GLU C 221 2.341 -35.332 55.355 1.00137.86 C +ATOM 5424 CG GLU C 221 2.277 -35.109 53.854 1.00157.44 C +ATOM 5425 CD GLU C 221 1.715 -36.301 53.086 1.00157.22 C +ATOM 5426 OE1 GLU C 221 2.001 -37.474 53.453 1.00102.70 O +ATOM 5427 OE2 GLU C 221 1.037 -36.036 52.067 1.00156.15 O +ATOM 5428 N THR C 222 3.316 -35.491 58.218 1.00 99.24 N +ATOM 5429 CA THR C 222 3.208 -35.668 59.657 1.00 86.89 C +ATOM 5430 C THR C 222 3.808 -34.485 60.408 1.00 95.08 C +ATOM 5431 O THR C 222 3.194 -33.951 61.343 1.00 87.48 O +ATOM 5432 CB THR C 222 3.949 -36.958 60.094 1.00 85.92 C +ATOM 5433 OG1 THR C 222 3.221 -38.107 59.631 1.00 92.33 O +ATOM 5434 CG2 THR C 222 4.145 -37.009 61.627 1.00 81.54 C +ATOM 5435 N GLY C 223 5.037 -34.116 60.032 1.00 99.61 N +ATOM 5436 CA GLY C 223 5.718 -32.957 60.619 1.00105.49 C +ATOM 5437 C GLY C 223 4.933 -31.653 60.489 1.00102.93 C +ATOM 5438 O GLY C 223 4.854 -30.867 61.446 1.00 89.43 O +ATOM 5439 N VAL C 224 4.290 -31.467 59.339 1.00 86.78 N +ATOM 5440 CA VAL C 224 3.493 -30.282 59.122 1.00 92.83 C +ATOM 5441 C VAL C 224 2.318 -30.259 60.091 1.00122.16 C +ATOM 5442 O VAL C 224 1.993 -29.209 60.662 1.00133.91 O +ATOM 5443 CB VAL C 224 2.973 -30.201 57.683 1.00 90.45 C +ATOM 5444 CG1 VAL C 224 2.006 -29.036 57.534 1.00 88.27 C +ATOM 5445 CG2 VAL C 224 4.136 -30.049 56.713 1.00103.18 C +ATOM 5446 N ILE C 225 1.685 -31.413 60.289 1.00148.49 N +ATOM 5447 CA ILE C 225 0.559 -31.500 61.225 1.00150.73 C +ATOM 5448 C ILE C 225 1.000 -31.139 62.638 1.00139.46 C +ATOM 5449 O ILE C 225 0.399 -30.252 63.252 1.00118.30 O +ATOM 5450 CB ILE C 225 -0.094 -32.894 61.233 1.00145.66 C +ATOM 5451 CG1 ILE C 225 -0.794 -33.153 59.896 1.00180.71 C +ATOM 5452 CG2 ILE C 225 -1.117 -32.995 62.356 1.00118.31 C +ATOM 5453 CD1 ILE C 225 -1.089 -34.615 59.637 1.00204.15 C +ATOM 5454 N PHE C 226 2.060 -31.790 63.127 1.00123.18 N +ATOM 5455 CA PHE C 226 2.615 -31.479 64.454 1.00132.01 C +ATOM 5456 C PHE C 226 2.975 -29.989 64.605 1.00147.47 C +ATOM 5457 O PHE C 226 2.832 -29.415 65.688 1.00165.20 O +ATOM 5458 CB PHE C 226 3.855 -32.324 64.759 1.00131.22 C +ATOM 5459 CG PHE C 226 3.554 -33.734 65.199 1.00113.13 C +ATOM 5460 CD1 PHE C 226 2.834 -33.971 66.343 1.00118.80 C +ATOM 5461 CD2 PHE C 226 4.094 -34.825 64.508 1.00114.78 C +ATOM 5462 CE1 PHE C 226 2.591 -35.272 66.754 1.00150.00 C +ATOM 5463 CE2 PHE C 226 3.898 -36.125 64.939 1.00 96.82 C +ATOM 5464 CZ PHE C 226 3.123 -36.349 66.047 1.00120.79 C +ATOM 5465 N LEU C 227 3.438 -29.365 63.525 1.00125.05 N +ATOM 5466 CA LEU C 227 3.725 -27.940 63.538 1.00117.04 C +ATOM 5467 C LEU C 227 2.455 -27.115 63.722 1.00142.13 C +ATOM 5468 O LEU C 227 2.443 -26.153 64.494 1.00146.61 O +ATOM 5469 CB LEU C 227 4.428 -27.551 62.241 1.00108.13 C +ATOM 5470 CG LEU C 227 5.910 -27.920 62.150 1.00115.00 C +ATOM 5471 CD1 LEU C 227 6.520 -27.802 60.773 1.00118.55 C +ATOM 5472 CD2 LEU C 227 6.737 -27.110 63.126 1.00126.63 C +ATOM 5473 N ILE C 228 1.396 -27.463 62.988 1.00138.87 N +ATOM 5474 CA ILE C 228 0.139 -26.712 63.056 1.00123.88 C +ATOM 5475 C ILE C 228 -0.447 -26.852 64.454 1.00120.59 C +ATOM 5476 O ILE C 228 -0.856 -25.866 65.074 1.00 86.83 O +ATOM 5477 CB ILE C 228 -0.903 -27.187 62.020 1.00103.07 C +ATOM 5478 CG1 ILE C 228 -0.411 -26.924 60.601 1.00121.93 C +ATOM 5479 CG2 ILE C 228 -2.213 -26.444 62.212 1.00 86.71 C +ATOM 5480 CD1 ILE C 228 -1.173 -27.673 59.527 1.00139.66 C +ATOM 5481 N ASN C 229 -0.490 -28.085 64.944 1.00127.67 N +ATOM 5482 CA ASN C 229 -1.058 -28.366 66.259 1.00144.10 C +ATOM 5483 C ASN C 229 -0.281 -27.604 67.328 1.00144.73 C +ATOM 5484 O ASN C 229 -0.871 -27.008 68.234 1.00130.89 O +ATOM 5485 CB ASN C 229 -1.032 -29.877 66.525 1.00152.30 C +ATOM 5486 CG ASN C 229 -1.927 -30.287 67.671 1.00163.78 C +ATOM 5487 OD1 ASN C 229 -2.895 -29.596 68.010 1.00170.63 O +ATOM 5488 ND2 ASN C 229 -1.631 -31.441 68.256 1.00172.28 N +ATOM 5489 N ASP C 230 1.045 -27.610 67.197 1.00142.29 N +ATOM 5490 CA ASP C 230 1.925 -26.930 68.146 1.00147.34 C +ATOM 5491 C ASP C 230 1.675 -25.432 68.118 1.00121.51 C +ATOM 5492 O ASP C 230 1.601 -24.784 69.170 1.00146.37 O +ATOM 5493 CB ASP C 230 3.393 -27.212 67.810 1.00162.06 C +ATOM 5494 CG ASP C 230 4.352 -26.626 68.836 1.00179.86 C +ATOM 5495 OD1 ASP C 230 4.418 -27.174 69.954 1.00214.46 O +ATOM 5496 OD2 ASP C 230 5.007 -25.612 68.547 1.00150.37 O +ATOM 5497 N GLY C 231 1.478 -24.902 66.920 1.00103.02 N +ATOM 5498 CA GLY C 231 1.176 -23.483 66.762 1.00134.84 C +ATOM 5499 C GLY C 231 -0.191 -23.074 67.299 1.00142.26 C +ATOM 5500 O GLY C 231 -0.343 -21.989 67.884 1.00105.81 O +ATOM 5501 N ILE C 232 -1.158 -23.988 67.200 1.00173.44 N +ATOM 5502 CA ILE C 232 -2.476 -23.798 67.823 1.00168.20 C +ATOM 5503 C ILE C 232 -2.360 -23.682 69.344 1.00165.21 C +ATOM 5504 O ILE C 232 -2.863 -22.720 69.926 1.00156.79 O +ATOM 5505 CB ILE C 232 -3.449 -24.950 67.471 1.00159.91 C +ATOM 5506 CG1 ILE C 232 -3.868 -24.835 66.001 1.00174.18 C +ATOM 5507 CG2 ILE C 232 -4.673 -24.939 68.384 1.00139.38 C +ATOM 5508 CD1 ILE C 232 -4.463 -26.104 65.431 1.00178.20 C +ATOM 5509 N ASP C 233 -1.671 -24.644 69.965 1.00165.17 N +ATOM 5510 CA ASP C 233 -1.399 -24.624 71.413 1.00153.14 C +ATOM 5511 C ASP C 233 -0.701 -23.336 71.866 1.00145.30 C +ATOM 5512 O ASP C 233 -1.152 -22.675 72.792 1.00166.16 O +ATOM 5513 CB ASP C 233 -0.526 -25.816 71.821 1.00150.74 C +ATOM 5514 CG ASP C 233 -1.217 -27.156 71.610 1.00179.63 C +ATOM 5515 OD1 ASP C 233 -2.302 -27.196 70.973 1.00199.02 O +ATOM 5516 OD2 ASP C 233 -0.668 -28.181 72.076 1.00176.77 O +ATOM 5517 N ARG C 234 0.361 -22.949 71.165 1.00129.53 N +ATOM 5518 CA ARG C 234 1.173 -21.795 71.569 1.00 98.55 C +ATOM 5519 C ARG C 234 0.587 -20.429 71.182 1.00122.40 C +ATOM 5520 O ARG C 234 1.199 -19.393 71.441 1.00135.30 O +ATOM 5521 CB ARG C 234 2.576 -21.952 71.007 1.00 84.19 C +ATOM 5522 CG ARG C 234 3.345 -23.030 71.724 1.00 93.82 C +ATOM 5523 CD ARG C 234 4.509 -23.579 70.904 1.00 97.07 C +ATOM 5524 NE ARG C 234 5.163 -24.667 71.619 1.00 95.06 N +ATOM 5525 CZ ARG C 234 6.414 -24.634 72.053 1.00100.12 C +ATOM 5526 NH1 ARG C 234 7.197 -23.616 71.739 1.00107.82 N +ATOM 5527 NH2 ARG C 234 6.897 -25.649 72.758 1.00108.16 N +ATOM 5528 N GLY C 235 -0.555 -20.426 70.491 1.00133.03 N +ATOM 5529 CA GLY C 235 -1.204 -19.183 70.082 1.00137.94 C +ATOM 5530 C GLY C 235 -0.539 -18.462 68.912 1.00160.72 C +ATOM 5531 O GLY C 235 -0.550 -17.226 68.854 1.00154.08 O +ATOM 5532 N LEU C 236 0.056 -19.213 67.983 1.00158.74 N +ATOM 5533 CA LEU C 236 0.519 -18.619 66.720 1.00137.70 C +ATOM 5534 C LEU C 236 -0.696 -18.319 65.853 1.00143.59 C +ATOM 5535 O LEU C 236 -0.826 -17.227 65.298 1.00137.84 O +ATOM 5536 CB LEU C 236 1.490 -19.546 65.964 1.00123.73 C +ATOM 5537 CG LEU C 236 2.973 -19.512 66.369 1.00113.75 C +ATOM 5538 CD1 LEU C 236 3.204 -20.313 67.632 1.00127.31 C +ATOM 5539 CD2 LEU C 236 3.831 -20.071 65.244 1.00125.16 C +ATOM 5540 N TRP C 237 -1.581 -19.302 65.732 1.00163.82 N +ATOM 5541 CA TRP C 237 -2.770 -19.175 64.887 1.00172.45 C +ATOM 5542 C TRP C 237 -3.982 -19.805 65.579 1.00186.40 C +ATOM 5543 O TRP C 237 -3.824 -20.566 66.540 1.00151.42 O +ATOM 5544 CB TRP C 237 -2.514 -19.813 63.516 1.00152.94 C +ATOM 5545 CG TRP C 237 -1.597 -21.000 63.586 1.00141.74 C +ATOM 5546 CD1 TRP C 237 -1.856 -22.194 64.182 1.00142.41 C +ATOM 5547 CD2 TRP C 237 -0.267 -21.094 63.061 1.00130.79 C +ATOM 5548 NE1 TRP C 237 -0.781 -23.032 64.049 1.00137.24 N +ATOM 5549 CE2 TRP C 237 0.203 -22.387 63.349 1.00124.18 C +ATOM 5550 CE3 TRP C 237 0.561 -20.218 62.356 1.00142.03 C +ATOM 5551 CZ2 TRP C 237 1.467 -22.830 62.957 1.00111.95 C +ATOM 5552 CZ3 TRP C 237 1.822 -20.660 61.976 1.00141.14 C +ATOM 5553 CH2 TRP C 237 2.263 -21.953 62.290 1.00114.68 C +ATOM 5554 N ASP C 238 -5.179 -19.494 65.077 1.00198.61 N +ATOM 5555 CA ASP C 238 -6.427 -19.903 65.731 1.00183.61 C +ATOM 5556 C ASP C 238 -7.418 -20.589 64.791 1.00165.75 C +ATOM 5557 O ASP C 238 -7.478 -20.286 63.590 1.00163.40 O +ATOM 5558 CB ASP C 238 -7.114 -18.702 66.371 1.00168.36 C +ATOM 5559 CG ASP C 238 -6.222 -17.975 67.350 1.00180.91 C +ATOM 5560 OD1 ASP C 238 -5.365 -17.194 66.891 1.00163.76 O +ATOM 5561 OD2 ASP C 238 -6.364 -18.187 68.576 1.00196.60 O +ATOM 5562 N LEU C 239 -8.194 -21.517 65.354 1.00130.79 N +ATOM 5563 CA LEU C 239 -9.165 -22.289 64.587 1.00125.68 C +ATOM 5564 C LEU C 239 -10.389 -21.447 64.300 1.00121.19 C +ATOM 5565 O LEU C 239 -10.795 -20.620 65.121 1.00150.31 O +ATOM 5566 CB LEU C 239 -9.585 -23.555 65.348 1.00127.43 C +ATOM 5567 CG LEU C 239 -8.648 -24.763 65.389 1.00133.65 C +ATOM 5568 CD1 LEU C 239 -9.308 -25.934 66.097 1.00139.32 C +ATOM 5569 CD2 LEU C 239 -8.247 -25.174 63.988 1.00150.74 C +ATOM 5570 N GLN C 240 -10.977 -21.665 63.128 1.00125.56 N +ATOM 5571 CA GLN C 240 -12.275 -21.080 62.800 1.00148.07 C +ATOM 5572 C GLN C 240 -13.302 -21.444 63.869 1.00170.50 C +ATOM 5573 O GLN C 240 -13.917 -20.570 64.487 1.00158.12 O +ATOM 5574 CB GLN C 240 -12.749 -21.574 61.424 1.00151.84 C +ATOM 5575 CG GLN C 240 -13.999 -20.869 60.912 1.00151.76 C +ATOM 5576 CD GLN C 240 -13.755 -19.392 60.642 1.00156.01 C +ATOM 5577 OE1 GLN C 240 -13.201 -19.024 59.600 1.00192.76 O +ATOM 5578 NE2 GLN C 240 -14.123 -18.542 61.597 1.00133.28 N +ATOM 5579 N ASN C 241 -13.461 -22.746 64.085 1.00200.66 N +ATOM 5580 CA ASN C 241 -14.382 -23.275 65.084 1.00196.28 C +ATOM 5581 C ASN C 241 -13.626 -23.766 66.306 1.00194.43 C +ATOM 5582 O ASN C 241 -12.947 -24.802 66.252 1.00194.69 O +ATOM 5583 CB ASN C 241 -15.179 -24.438 64.494 1.00197.04 C +ATOM 5584 CG ASN C 241 -16.569 -24.029 64.071 1.00199.13 C +ATOM 5585 OD1 ASN C 241 -17.534 -24.304 64.779 1.00208.28 O +ATOM 5586 ND2 ASN C 241 -16.679 -23.343 62.931 1.00180.84 N +ATOM 5587 N LYS C 242 -13.789 -23.053 67.419 1.00174.56 N +ATOM 5588 CA LYS C 242 -13.121 -23.425 68.665 1.00167.96 C +ATOM 5589 C LYS C 242 -13.660 -24.766 69.159 1.00162.70 C +ATOM 5590 O LYS C 242 -12.956 -25.524 69.839 1.00 93.20 O +ATOM 5591 CB LYS C 242 -13.306 -22.333 69.722 1.00153.59 C +ATOM 5592 CG LYS C 242 -12.984 -20.933 69.219 1.00163.85 C +ATOM 5593 CD LYS C 242 -11.958 -20.233 70.095 1.00185.93 C +ATOM 5594 CE LYS C 242 -10.871 -19.577 69.252 1.00217.26 C +ATOM 5595 NZ LYS C 242 -9.934 -18.752 70.063 1.00228.92 N +ATOM 5596 N ALA C 243 -14.897 -25.058 68.749 1.00194.97 N +ATOM 5597 CA ALA C 243 -15.549 -26.343 68.995 1.00216.18 C +ATOM 5598 C ALA C 243 -14.805 -27.494 68.330 1.00223.90 C +ATOM 5599 O ALA C 243 -15.001 -28.656 68.706 1.00266.74 O +ATOM 5600 CB ALA C 243 -16.991 -26.306 68.494 1.00226.39 C +ATOM 5601 N GLU C 244 -13.974 -27.183 67.333 1.00201.66 N +ATOM 5602 CA GLU C 244 -13.262 -28.230 66.606 1.00179.78 C +ATOM 5603 C GLU C 244 -11.890 -28.517 67.199 1.00160.17 C +ATOM 5604 O GLU C 244 -11.102 -29.211 66.579 1.00128.66 O +ATOM 5605 CB GLU C 244 -13.133 -27.870 65.125 1.00169.75 C +ATOM 5606 CG GLU C 244 -14.431 -27.989 64.346 1.00171.55 C +ATOM 5607 CD GLU C 244 -14.225 -27.886 62.847 1.00166.03 C +ATOM 5608 OE1 GLU C 244 -14.030 -26.757 62.343 1.00180.09 O +ATOM 5609 OE2 GLU C 244 -14.277 -28.933 62.166 1.00144.77 O +ATOM 5610 N ARG C 245 -11.601 -27.972 68.383 1.00159.24 N +ATOM 5611 CA ARG C 245 -10.356 -28.290 69.087 1.00153.35 C +ATOM 5612 C ARG C 245 -10.180 -29.790 69.330 1.00163.39 C +ATOM 5613 O ARG C 245 -9.058 -30.295 69.269 1.00113.85 O +ATOM 5614 CB ARG C 245 -10.253 -27.569 70.422 1.00147.95 C +ATOM 5615 CG ARG C 245 -8.886 -27.734 71.092 1.00153.85 C +ATOM 5616 CD ARG C 245 -8.752 -26.924 72.393 1.00159.62 C +ATOM 5617 NE ARG C 245 -8.059 -25.655 72.168 1.00163.80 N +ATOM 5618 CZ ARG C 245 -6.755 -25.536 71.914 1.00171.11 C +ATOM 5619 NH1 ARG C 245 -5.983 -26.605 71.831 1.00154.00 N +ATOM 5620 NH2 ARG C 245 -6.216 -24.336 71.721 1.00198.75 N +ATOM 5621 N GLN C 246 -11.277 -30.495 69.618 1.00182.08 N +ATOM 5622 CA GLN C 246 -11.205 -31.928 69.938 1.00161.21 C +ATOM 5623 C GLN C 246 -11.422 -32.786 68.696 1.00152.47 C +ATOM 5624 O GLN C 246 -11.772 -33.955 68.800 1.00183.47 O +ATOM 5625 CB GLN C 246 -12.215 -32.306 71.026 1.00149.73 C +ATOM 5626 CG GLN C 246 -11.883 -31.776 72.409 1.00155.49 C +ATOM 5627 CD GLN C 246 -12.176 -30.292 72.542 1.00191.85 C +ATOM 5628 OE1 GLN C 246 -13.235 -29.814 72.118 1.00200.28 O +ATOM 5629 NE2 GLN C 246 -11.252 -29.558 73.157 1.00202.23 N +ATOM 5630 N ASN C 247 -11.202 -32.197 67.525 1.00147.28 N +ATOM 5631 CA ASN C 247 -11.083 -32.945 66.274 1.00153.15 C +ATOM 5632 C ASN C 247 -10.291 -34.250 66.441 1.00162.19 C +ATOM 5633 O ASN C 247 -9.248 -34.266 67.102 1.00173.06 O +ATOM 5634 CB ASN C 247 -10.385 -32.077 65.226 1.00155.47 C +ATOM 5635 CG ASN C 247 -10.765 -32.454 63.820 1.00148.66 C +ATOM 5636 OD1 ASN C 247 -9.951 -32.997 63.060 1.00136.78 O +ATOM 5637 ND2 ASN C 247 -11.997 -32.133 63.447 1.00140.66 N +ATOM 5638 N ASP C 248 -10.776 -35.328 65.823 1.00164.55 N +ATOM 5639 CA ASP C 248 -10.144 -36.656 65.944 1.00169.97 C +ATOM 5640 C ASP C 248 -8.650 -36.605 65.616 1.00187.83 C +ATOM 5641 O ASP C 248 -7.809 -37.176 66.326 1.00204.15 O +ATOM 5642 CB ASP C 248 -10.815 -37.665 64.998 1.00168.88 C +ATOM 5643 CG ASP C 248 -12.214 -38.051 65.440 1.00176.95 C +ATOM 5644 OD1 ASP C 248 -12.446 -38.199 66.657 1.00190.68 O +ATOM 5645 OD2 ASP C 248 -13.082 -38.228 64.559 1.00159.09 O +ATOM 5646 N ILE C 249 -8.334 -35.943 64.508 1.00189.07 N +ATOM 5647 CA ILE C 249 -6.971 -35.873 64.010 1.00160.80 C +ATOM 5648 C ILE C 249 -6.109 -35.072 64.991 1.00143.84 C +ATOM 5649 O ILE C 249 -5.029 -35.516 65.406 1.00166.24 O +ATOM 5650 CB ILE C 249 -6.937 -35.231 62.606 1.00154.96 C +ATOM 5651 CG1 ILE C 249 -7.714 -36.100 61.601 1.00139.41 C +ATOM 5652 CG2 ILE C 249 -5.501 -35.065 62.135 1.00169.85 C +ATOM 5653 CD1 ILE C 249 -8.157 -35.362 60.355 1.00134.78 C +ATOM 5654 N LEU C 250 -6.607 -33.901 65.379 1.00119.31 N +ATOM 5655 CA LEU C 250 -5.860 -33.005 66.266 1.00131.91 C +ATOM 5656 C LEU C 250 -5.546 -33.644 67.615 1.00151.83 C +ATOM 5657 O LEU C 250 -4.464 -33.430 68.172 1.00160.71 O +ATOM 5658 CB LEU C 250 -6.622 -31.696 66.475 1.00119.92 C +ATOM 5659 CG LEU C 250 -6.490 -30.672 65.339 1.00131.45 C +ATOM 5660 CD1 LEU C 250 -7.490 -29.536 65.466 1.00116.62 C +ATOM 5661 CD2 LEU C 250 -5.075 -30.113 65.305 1.00151.65 C +ATOM 5662 N VAL C 251 -6.493 -34.419 68.140 1.00170.34 N +ATOM 5663 CA VAL C 251 -6.291 -35.098 69.424 1.00164.65 C +ATOM 5664 C VAL C 251 -5.397 -36.326 69.268 1.00162.65 C +ATOM 5665 O VAL C 251 -4.745 -36.757 70.223 1.00193.36 O +ATOM 5666 CB VAL C 251 -7.622 -35.504 70.094 1.00149.80 C +ATOM 5667 CG1 VAL C 251 -8.531 -34.289 70.258 1.00139.15 C +ATOM 5668 CG2 VAL C 251 -8.316 -36.619 69.320 1.00145.17 C +ATOM 5669 N LYS C 252 -5.364 -36.884 68.062 1.00134.05 N +ATOM 5670 CA LYS C 252 -4.476 -38.008 67.767 1.00134.87 C +ATOM 5671 C LYS C 252 -3.004 -37.561 67.812 1.00141.64 C +ATOM 5672 O LYS C 252 -2.161 -38.205 68.446 1.00115.30 O +ATOM 5673 CB LYS C 252 -4.845 -38.597 66.403 1.00139.06 C +ATOM 5674 CG LYS C 252 -3.984 -39.762 65.938 1.00131.86 C +ATOM 5675 CD LYS C 252 -4.441 -40.228 64.560 1.00147.33 C +ATOM 5676 CE LYS C 252 -3.264 -40.411 63.613 1.00150.48 C +ATOM 5677 NZ LYS C 252 -3.699 -40.602 62.201 1.00172.70 N +ATOM 5678 N TYR C 253 -2.719 -36.422 67.185 1.00159.87 N +ATOM 5679 CA TYR C 253 -1.356 -35.880 67.138 1.00151.73 C +ATOM 5680 C TYR C 253 -0.989 -35.208 68.448 1.00141.48 C +ATOM 5681 O TYR C 253 0.175 -35.225 68.858 1.00179.80 O +ATOM 5682 CB TYR C 253 -1.192 -34.905 65.960 1.00153.52 C +ATOM 5683 CG TYR C 253 -1.159 -35.625 64.623 1.00150.31 C +ATOM 5684 CD1 TYR C 253 0.037 -36.109 64.086 1.00136.74 C +ATOM 5685 CD2 TYR C 253 -2.336 -35.895 63.939 1.00153.52 C +ATOM 5686 CE1 TYR C 253 0.034 -36.803 62.885 1.00138.47 C +ATOM 5687 CE2 TYR C 253 -2.342 -36.599 62.748 1.00134.70 C +ATOM 5688 CZ TYR C 253 -1.159 -37.056 62.229 1.00131.92 C +ATOM 5689 OH TYR C 253 -1.164 -37.756 61.036 1.00135.74 O +ATOM 5690 N ARG C 254 -1.988 -34.634 69.108 1.00156.09 N +ATOM 5691 CA ARG C 254 -1.826 -34.150 70.481 1.00166.96 C +ATOM 5692 C ARG C 254 -1.393 -35.293 71.403 1.00181.78 C +ATOM 5693 O ARG C 254 -0.528 -35.111 72.267 1.00187.35 O +ATOM 5694 CB ARG C 254 -3.135 -33.546 71.006 1.00149.40 C +ATOM 5695 CG ARG C 254 -3.001 -32.915 72.380 1.00140.35 C +ATOM 5696 CD ARG C 254 -4.146 -31.973 72.707 1.00159.59 C +ATOM 5697 NE ARG C 254 -4.198 -30.780 71.856 1.00174.85 N +ATOM 5698 CZ ARG C 254 -5.107 -30.544 70.910 1.00165.58 C +ATOM 5699 NH1 ARG C 254 -6.059 -31.426 70.646 1.00164.34 N +ATOM 5700 NH2 ARG C 254 -5.067 -29.406 70.226 1.00156.00 N +ATOM 5701 N HIS C 255 -1.982 -36.472 71.188 1.00210.95 N +ATOM 5702 CA HIS C 255 -1.669 -37.666 71.981 1.00208.78 C +ATOM 5703 C HIS C 255 -0.265 -38.205 71.723 1.00170.34 C +ATOM 5704 O HIS C 255 0.395 -38.694 72.640 1.00123.86 O +ATOM 5705 CB HIS C 255 -2.701 -38.777 71.731 1.00223.21 C +ATOM 5706 CG HIS C 255 -3.667 -38.972 72.857 1.00229.56 C +ATOM 5707 ND1 HIS C 255 -4.701 -38.097 73.111 1.00229.70 N +ATOM 5708 CD2 HIS C 255 -3.751 -39.940 73.801 1.00230.85 C +ATOM 5709 CE1 HIS C 255 -5.380 -38.517 74.165 1.00238.92 C +ATOM 5710 NE2 HIS C 255 -4.823 -39.633 74.603 1.00231.87 N +ATOM 5711 N MET C 256 0.203 -38.097 70.486 1.00156.30 N +ATOM 5712 CA MET C 256 1.559 -38.546 70.178 1.00174.27 C +ATOM 5713 C MET C 256 2.631 -37.689 70.897 1.00164.44 C +ATOM 5714 O MET C 256 3.752 -38.160 71.131 1.00126.43 O +ATOM 5715 CB MET C 256 1.777 -38.590 68.649 1.00180.54 C +ATOM 5716 CG MET C 256 0.718 -39.395 67.899 1.00156.74 C +ATOM 5717 SD MET C 256 1.177 -39.934 66.237 1.00149.05 S +ATOM 5718 CE MET C 256 2.443 -41.146 66.625 1.00163.12 C +ATOM 5719 N SER C 257 2.285 -36.438 71.219 1.00153.25 N +ATOM 5720 CA SER C 257 3.177 -35.522 71.945 1.00130.28 C +ATOM 5721 C SER C 257 3.222 -35.850 73.432 1.00115.07 C +ATOM 5722 O SER C 257 4.046 -36.648 73.861 1.00122.38 O +ATOM 5723 CB SER C 257 2.718 -34.067 71.771 1.00144.19 C +ATOM 5724 OG SER C 257 2.357 -33.784 70.433 1.00133.00 O +TER 5725 SER C 257 +ATOM 5726 N LEU D 2 -1.174 -54.832 41.107 1.00100.19 N +ATOM 5727 CA LEU D 2 0.085 -54.759 41.911 1.00109.70 C +ATOM 5728 C LEU D 2 1.303 -54.584 40.983 1.00124.57 C +ATOM 5729 O LEU D 2 2.146 -55.502 40.805 1.00 95.99 O +ATOM 5730 CB LEU D 2 0.243 -55.989 42.818 1.00126.50 C +ATOM 5731 CG LEU D 2 -0.822 -56.250 43.912 1.00148.69 C +ATOM 5732 CD1 LEU D 2 -0.471 -57.531 44.666 1.00154.58 C +ATOM 5733 CD2 LEU D 2 -1.031 -55.101 44.906 1.00139.92 C +ATOM 5734 N THR D 3 1.289 -53.435 40.301 1.00140.38 N +ATOM 5735 CA THR D 3 2.471 -52.844 39.659 1.00127.20 C +ATOM 5736 C THR D 3 2.485 -51.313 39.856 1.00110.17 C +ATOM 5737 O THR D 3 3.420 -50.629 39.459 1.00105.55 O +ATOM 5738 CB THR D 3 2.520 -53.131 38.144 1.00118.01 C +ATOM 5739 OG1 THR D 3 1.471 -52.409 37.479 1.00 97.46 O +ATOM 5740 CG2 THR D 3 2.423 -54.639 37.863 1.00106.42 C +ATOM 5741 N ALA D 4 1.431 -50.782 40.459 1.00107.47 N +ATOM 5742 CA ALA D 4 1.504 -49.495 41.156 1.00 92.49 C +ATOM 5743 C ALA D 4 2.260 -49.694 42.496 1.00 87.18 C +ATOM 5744 O ALA D 4 2.806 -50.762 42.750 1.00 70.62 O +ATOM 5745 CB ALA D 4 0.103 -48.942 41.374 1.00 98.67 C +ATOM 5746 N PRO D 5 2.326 -48.670 43.351 1.00 92.72 N +ATOM 5747 CA PRO D 5 3.351 -48.878 44.368 1.00109.07 C +ATOM 5748 C PRO D 5 2.842 -49.701 45.545 1.00122.73 C +ATOM 5749 O PRO D 5 1.647 -49.967 45.627 1.00164.64 O +ATOM 5750 CB PRO D 5 3.675 -47.455 44.811 1.00158.90 C +ATOM 5751 CG PRO D 5 2.433 -46.646 44.524 1.00148.25 C +ATOM 5752 CD PRO D 5 1.630 -47.374 43.489 1.00108.89 C +ATOM 5753 N PRO D 6 3.748 -50.139 46.438 1.00123.07 N +ATOM 5754 CA PRO D 6 3.353 -50.672 47.758 1.00126.13 C +ATOM 5755 C PRO D 6 2.999 -49.576 48.752 1.00128.62 C +ATOM 5756 O PRO D 6 3.512 -48.461 48.648 1.00155.44 O +ATOM 5757 CB PRO D 6 4.582 -51.456 48.231 1.00102.31 C +ATOM 5758 CG PRO D 6 5.712 -50.988 47.390 1.00 98.76 C +ATOM 5759 CD PRO D 6 5.185 -50.282 46.171 1.00103.18 C +ATOM 5760 N LYS D 7 2.118 -49.881 49.700 1.00128.11 N +ATOM 5761 CA LYS D 7 1.633 -48.858 50.628 1.00150.88 C +ATOM 5762 C LYS D 7 2.416 -48.858 51.939 1.00146.22 C +ATOM 5763 O LYS D 7 3.213 -49.784 52.202 1.00 96.55 O +ATOM 5764 CB LYS D 7 0.120 -48.989 50.865 1.00157.21 C +ATOM 5765 CG LYS D 7 -0.683 -48.490 49.621 1.00166.70 C +ATOM 5766 CD LYS D 7 -0.658 -46.960 49.486 1.00172.15 C +ATOM 5767 CE LYS D 7 -0.871 -46.525 48.038 1.00165.36 C +ATOM 5768 NZ LYS D 7 -1.488 -45.172 47.937 1.00169.59 N +ATOM 5769 N GLU D 8 2.196 -47.798 52.730 1.00151.29 N +ATOM 5770 CA GLU D 8 3.017 -47.500 53.909 1.00142.12 C +ATOM 5771 C GLU D 8 2.904 -48.573 54.993 1.00125.15 C +ATOM 5772 O GLU D 8 1.841 -48.820 55.528 1.00103.81 O +ATOM 5773 CB GLU D 8 2.712 -46.088 54.502 1.00127.74 C +ATOM 5774 CG GLU D 8 1.511 -45.934 55.413 1.00135.77 C +ATOM 5775 CD GLU D 8 1.466 -44.570 56.104 1.00146.60 C +ATOM 5776 OE1 GLU D 8 2.439 -44.192 56.790 1.00180.11 O +ATOM 5777 OE2 GLU D 8 0.441 -43.877 56.022 1.00134.68 O +ATOM 5778 N ALA D 9 4.024 -49.223 55.281 1.00121.43 N +ATOM 5779 CA ALA D 9 4.137 -50.145 56.397 1.00 93.70 C +ATOM 5780 C ALA D 9 4.710 -49.404 57.617 1.00108.77 C +ATOM 5781 O ALA D 9 5.870 -48.986 57.612 1.00127.75 O +ATOM 5782 CB ALA D 9 5.037 -51.303 56.002 1.00 77.72 C +ATOM 5783 N ALA D 10 3.890 -49.280 58.660 1.00108.15 N +ATOM 5784 CA ALA D 10 4.177 -48.470 59.862 1.00108.93 C +ATOM 5785 C ALA D 10 3.817 -47.014 59.612 1.00108.67 C +ATOM 5786 O ALA D 10 3.696 -46.581 58.468 1.00 94.32 O +ATOM 5787 CB ALA D 10 5.626 -48.594 60.328 1.00104.44 C +ATOM 5788 N ARG D 11 3.593 -46.278 60.695 1.00120.25 N +ATOM 5789 CA ARG D 11 3.177 -44.867 60.618 1.00132.26 C +ATOM 5790 C ARG D 11 4.378 -43.977 60.915 1.00131.68 C +ATOM 5791 O ARG D 11 5.279 -44.389 61.634 1.00102.37 O +ATOM 5792 CB ARG D 11 2.070 -44.563 61.644 1.00143.07 C +ATOM 5793 CG ARG D 11 2.505 -44.674 63.100 1.00151.89 C +ATOM 5794 CD ARG D 11 1.335 -44.986 64.028 1.00143.73 C +ATOM 5795 NE ARG D 11 1.507 -46.277 64.695 1.00179.44 N +ATOM 5796 CZ ARG D 11 0.676 -46.756 65.617 1.00184.89 C +ATOM 5797 NH1 ARG D 11 -0.397 -46.060 65.960 1.00211.46 N +ATOM 5798 NH2 ARG D 11 0.904 -47.937 66.185 1.00145.14 N +ATOM 5799 N PRO D 12 4.395 -42.750 60.367 1.00119.02 N +ATOM 5800 CA PRO D 12 5.377 -41.797 60.843 1.00 99.04 C +ATOM 5801 C PRO D 12 5.063 -41.451 62.291 1.00 97.97 C +ATOM 5802 O PRO D 12 4.000 -40.888 62.587 1.00103.62 O +ATOM 5803 CB PRO D 12 5.184 -40.579 59.924 1.00 85.45 C +ATOM 5804 CG PRO D 12 4.368 -41.051 58.786 1.00 95.38 C +ATOM 5805 CD PRO D 12 3.527 -42.174 59.330 1.00116.34 C +ATOM 5806 N THR D 13 5.948 -41.846 63.193 1.00 77.14 N +ATOM 5807 CA THR D 13 5.896 -41.353 64.559 1.00 94.02 C +ATOM 5808 C THR D 13 6.774 -40.116 64.708 1.00 92.03 C +ATOM 5809 O THR D 13 7.676 -39.904 63.890 1.00139.89 O +ATOM 5810 CB THR D 13 6.382 -42.439 65.521 1.00103.05 C +ATOM 5811 OG1 THR D 13 6.122 -42.027 66.871 1.00112.00 O +ATOM 5812 CG2 THR D 13 7.904 -42.759 65.308 1.00 83.50 C +ATOM 5813 N LEU D 14 6.563 -39.310 65.744 1.00 72.29 N +ATOM 5814 CA LEU D 14 7.586 -38.314 66.039 1.00 64.88 C +ATOM 5815 C LEU D 14 8.818 -39.013 66.660 1.00 54.24 C +ATOM 5816 O LEU D 14 8.746 -40.135 67.092 1.00 41.23 O +ATOM 5817 CB LEU D 14 7.056 -37.132 66.856 1.00 75.39 C +ATOM 5818 CG LEU D 14 6.346 -37.416 68.159 1.00 97.07 C +ATOM 5819 CD1 LEU D 14 6.605 -36.305 69.176 1.00 93.69 C +ATOM 5820 CD2 LEU D 14 4.870 -37.536 67.878 1.00103.26 C +ATOM 5821 N MET D 15 9.977 -38.389 66.598 1.00 69.58 N +ATOM 5822 CA MET D 15 11.244 -39.141 66.597 1.00 92.18 C +ATOM 5823 C MET D 15 11.518 -39.763 67.961 1.00 79.48 C +ATOM 5824 O MET D 15 11.586 -39.050 68.962 1.00 75.99 O +ATOM 5825 CB MET D 15 12.433 -38.246 66.133 1.00124.63 C +ATOM 5826 CG MET D 15 13.551 -39.017 65.425 1.00128.03 C +ATOM 5827 SD MET D 15 15.269 -38.466 65.565 1.00121.12 S +ATOM 5828 CE MET D 15 15.320 -37.546 67.111 1.00133.50 C +ATOM 5829 N PRO D 16 11.731 -41.087 67.989 1.00 93.62 N +ATOM 5830 CA PRO D 16 11.862 -41.887 69.213 1.00114.32 C +ATOM 5831 C PRO D 16 13.075 -41.561 70.097 1.00102.47 C +ATOM 5832 O PRO D 16 14.091 -42.246 70.056 1.00 68.81 O +ATOM 5833 CB PRO D 16 11.953 -43.326 68.685 1.00115.79 C +ATOM 5834 CG PRO D 16 12.468 -43.185 67.306 1.00115.03 C +ATOM 5835 CD PRO D 16 11.843 -41.924 66.786 1.00107.60 C +ATOM 5836 N ARG D 17 12.942 -40.510 70.901 1.00116.49 N +ATOM 5837 CA ARG D 17 13.956 -40.149 71.889 1.00117.72 C +ATOM 5838 C ARG D 17 13.665 -40.877 73.194 1.00116.32 C +ATOM 5839 O ARG D 17 12.511 -41.116 73.506 1.00129.55 O +ATOM 5840 CB ARG D 17 13.944 -38.633 72.114 1.00130.21 C +ATOM 5841 CG ARG D 17 14.822 -37.868 71.138 1.00154.51 C +ATOM 5842 CD ARG D 17 14.500 -36.380 71.080 1.00153.11 C +ATOM 5843 NE ARG D 17 13.305 -36.110 70.286 1.00156.37 N +ATOM 5844 CZ ARG D 17 12.752 -34.908 70.165 1.00187.14 C +ATOM 5845 NH1 ARG D 17 13.306 -33.865 70.777 1.00200.46 N +ATOM 5846 NH2 ARG D 17 11.660 -34.745 69.424 1.00171.24 N +ATOM 5847 N ALA D 18 14.701 -41.254 73.940 1.00151.97 N +ATOM 5848 CA ALA D 18 14.513 -42.048 75.168 1.00146.95 C +ATOM 5849 C ALA D 18 14.887 -41.289 76.450 1.00143.67 C +ATOM 5850 O ALA D 18 14.281 -40.260 76.759 1.00 99.36 O +ATOM 5851 CB ALA D 18 15.260 -43.377 75.077 1.00140.72 C +ATOM 5852 N GLN D 19 15.877 -41.796 77.190 1.00147.47 N +ATOM 5853 CA GLN D 19 16.047 -41.418 78.597 1.00157.42 C +ATOM 5854 C GLN D 19 16.541 -39.981 78.744 1.00146.19 C +ATOM 5855 O GLN D 19 15.995 -39.181 79.519 1.00114.98 O +ATOM 5856 CB GLN D 19 17.022 -42.379 79.291 1.00150.82 C +ATOM 5857 CG GLN D 19 17.151 -42.164 80.792 1.00164.65 C +ATOM 5858 CD GLN D 19 15.809 -42.203 81.505 1.00179.98 C +ATOM 5859 OE1 GLN D 19 15.158 -43.243 81.571 1.00187.64 O +ATOM 5860 NE2 GLN D 19 15.379 -41.056 82.024 1.00198.93 N +ATOM 5861 N SER D 20 17.613 -39.688 78.019 1.00143.38 N +ATOM 5862 CA SER D 20 18.153 -38.350 77.924 1.00131.39 C +ATOM 5863 C SER D 20 17.022 -37.324 77.779 1.00123.56 C +ATOM 5864 O SER D 20 16.992 -36.317 78.494 1.00 96.83 O +ATOM 5865 CB SER D 20 19.116 -38.283 76.726 1.00146.00 C +ATOM 5866 OG SER D 20 20.068 -39.338 76.779 1.00136.41 O +ATOM 5867 N TYR D 21 16.121 -37.572 76.826 1.00134.52 N +ATOM 5868 CA TYR D 21 14.975 -36.690 76.568 1.00155.28 C +ATOM 5869 C TYR D 21 14.100 -36.498 77.808 1.00153.20 C +ATOM 5870 O TYR D 21 13.753 -35.366 78.169 1.00141.48 O +ATOM 5871 CB TYR D 21 14.120 -37.257 75.435 1.00160.94 C +ATOM 5872 CG TYR D 21 12.927 -36.394 75.097 1.00159.31 C +ATOM 5873 CD1 TYR D 21 13.087 -35.225 74.374 1.00162.34 C +ATOM 5874 CD2 TYR D 21 11.642 -36.734 75.530 1.00124.20 C +ATOM 5875 CE1 TYR D 21 11.998 -34.436 74.069 1.00163.60 C +ATOM 5876 CE2 TYR D 21 10.548 -35.955 75.218 1.00 91.80 C +ATOM 5877 CZ TYR D 21 10.730 -34.812 74.493 1.00 99.71 C +ATOM 5878 OH TYR D 21 9.682 -34.002 74.145 1.00 79.33 O +ATOM 5879 N LYS D 22 13.755 -37.607 78.452 1.00135.91 N +ATOM 5880 CA LYS D 22 12.885 -37.573 79.614 1.00145.33 C +ATOM 5881 C LYS D 22 13.485 -36.746 80.743 1.00139.82 C +ATOM 5882 O LYS D 22 12.774 -36.013 81.441 1.00124.35 O +ATOM 5883 CB LYS D 22 12.601 -39.001 80.105 1.00181.42 C +ATOM 5884 CG LYS D 22 11.391 -39.668 79.449 1.00221.02 C +ATOM 5885 CD LYS D 22 10.140 -39.627 80.317 1.00209.83 C +ATOM 5886 CE LYS D 22 8.799 -39.600 79.745 1.00188.16 C +ATOM 5887 NZ LYS D 22 8.109 -40.874 80.023 1.00192.42 N +ATOM 5888 N ASP D 23 14.791 -36.898 80.944 1.00141.05 N +ATOM 5889 CA ASP D 23 15.517 -36.095 81.927 1.00135.55 C +ATOM 5890 C ASP D 23 15.485 -34.625 81.526 1.00122.27 C +ATOM 5891 O ASP D 23 15.265 -33.742 82.360 1.00113.37 O +ATOM 5892 CB ASP D 23 16.978 -36.571 82.041 1.00125.51 C +ATOM 5893 CG ASP D 23 17.094 -37.928 82.669 1.00127.28 C +ATOM 5894 OD1 ASP D 23 16.347 -38.190 83.640 1.00138.21 O +ATOM 5895 OD2 ASP D 23 17.901 -38.748 82.180 1.00129.64 O +ATOM 5896 N LEU D 24 15.747 -34.378 80.247 1.00118.88 N +ATOM 5897 CA LEU D 24 15.920 -33.025 79.721 1.00147.50 C +ATOM 5898 C LEU D 24 14.626 -32.216 79.815 1.00142.31 C +ATOM 5899 O LEU D 24 14.659 -30.994 80.061 1.00130.54 O +ATOM 5900 CB LEU D 24 16.385 -33.096 78.257 1.00169.86 C +ATOM 5901 CG LEU D 24 16.620 -31.776 77.505 1.00160.62 C +ATOM 5902 CD1 LEU D 24 18.029 -31.249 77.749 1.00143.88 C +ATOM 5903 CD2 LEU D 24 16.369 -31.971 76.018 1.00145.23 C +ATOM 5904 N THR D 25 13.494 -32.898 79.627 1.00143.67 N +ATOM 5905 CA THR D 25 12.179 -32.240 79.644 1.00156.04 C +ATOM 5906 C THR D 25 11.704 -31.902 81.057 1.00167.90 C +ATOM 5907 O THR D 25 11.298 -30.763 81.330 1.00136.96 O +ATOM 5908 CB THR D 25 11.109 -33.111 78.968 1.00136.96 C +ATOM 5909 OG1 THR D 25 11.219 -34.458 79.436 1.00109.49 O +ATOM 5910 CG2 THR D 25 11.289 -33.087 77.467 1.00141.77 C +ATOM 5911 N HIS D 26 11.845 -32.869 81.963 1.00172.57 N +ATOM 5912 CA HIS D 26 11.432 -32.705 83.357 1.00167.13 C +ATOM 5913 C HIS D 26 12.519 -32.028 84.216 1.00154.68 C +ATOM 5914 O HIS D 26 12.686 -32.338 85.388 1.00151.45 O +ATOM 5915 CB HIS D 26 11.033 -34.070 83.936 1.00170.15 C +ATOM 5916 CG HIS D 26 9.851 -34.688 83.242 1.00156.10 C +ATOM 5917 ND1 HIS D 26 9.913 -35.167 81.950 1.00155.60 N +ATOM 5918 CD2 HIS D 26 8.569 -34.868 83.645 1.00144.18 C +ATOM 5919 CE1 HIS D 26 8.733 -35.651 81.602 1.00136.67 C +ATOM 5920 NE2 HIS D 26 7.893 -35.458 82.603 1.00123.91 N +ATOM 5921 N LEU D 27 13.230 -31.068 83.637 1.00156.91 N +ATOM 5922 CA LEU D 27 14.187 -30.266 84.392 1.00136.69 C +ATOM 5923 C LEU D 27 13.500 -29.044 84.993 1.00131.32 C +ATOM 5924 O LEU D 27 12.699 -28.376 84.329 1.00103.02 O +ATOM 5925 CB LEU D 27 15.331 -29.797 83.495 1.00159.56 C +ATOM 5926 CG LEU D 27 16.504 -30.769 83.371 1.00175.13 C +ATOM 5927 CD1 LEU D 27 17.421 -30.365 82.228 1.00178.06 C +ATOM 5928 CD2 LEU D 27 17.283 -30.850 84.676 1.00182.05 C +ATOM 5929 N PRO D 28 13.813 -28.742 86.264 1.00129.50 N +ATOM 5930 CA PRO D 28 13.172 -27.616 86.969 1.00140.99 C +ATOM 5931 C PRO D 28 13.471 -26.305 86.271 1.00118.24 C +ATOM 5932 O PRO D 28 14.620 -26.033 86.001 1.00139.04 O +ATOM 5933 CB PRO D 28 13.828 -27.651 88.360 1.00134.71 C +ATOM 5934 CG PRO D 28 15.114 -28.394 88.160 1.00111.07 C +ATOM 5935 CD PRO D 28 14.823 -29.412 87.102 1.00110.07 C +ATOM 5936 N ALA D 29 12.446 -25.503 86.007 1.00124.64 N +ATOM 5937 CA ALA D 29 12.590 -24.341 85.141 1.00125.01 C +ATOM 5938 C ALA D 29 13.380 -23.191 85.809 1.00134.34 C +ATOM 5939 O ALA D 29 13.344 -23.019 87.032 1.00124.30 O +ATOM 5940 CB ALA D 29 11.221 -23.863 84.663 1.00115.35 C +ATOM 5941 N PRO D 30 14.143 -22.429 85.003 1.00146.16 N +ATOM 5942 CA PRO D 30 14.880 -21.252 85.474 1.00146.85 C +ATOM 5943 C PRO D 30 13.961 -20.042 85.698 1.00134.59 C +ATOM 5944 O PRO D 30 12.772 -20.108 85.364 1.00 92.99 O +ATOM 5945 CB PRO D 30 15.826 -20.961 84.316 1.00146.05 C +ATOM 5946 CG PRO D 30 15.095 -21.437 83.106 1.00138.34 C +ATOM 5947 CD PRO D 30 14.263 -22.605 83.542 1.00144.99 C +ATOM 5948 N THR D 31 14.526 -18.936 86.197 1.00125.17 N +ATOM 5949 CA THR D 31 13.743 -17.714 86.474 1.00140.73 C +ATOM 5950 C THR D 31 13.235 -17.038 85.198 1.00134.43 C +ATOM 5951 O THR D 31 12.211 -16.367 85.208 1.00129.66 O +ATOM 5952 CB THR D 31 14.523 -16.670 87.320 1.00136.93 C +ATOM 5953 OG1 THR D 31 15.787 -16.383 86.720 1.00129.33 O +ATOM 5954 CG2 THR D 31 14.742 -17.171 88.742 1.00142.83 C +ATOM 5955 N GLY D 32 13.957 -17.232 84.105 1.00150.26 N +ATOM 5956 CA GLY D 32 13.463 -16.886 82.777 1.00167.77 C +ATOM 5957 C GLY D 32 14.214 -17.724 81.759 1.00166.70 C +ATOM 5958 O GLY D 32 15.324 -18.178 82.035 1.00157.30 O +ATOM 5959 N LYS D 33 13.625 -17.948 80.588 1.00141.90 N +ATOM 5960 CA LYS D 33 14.341 -18.665 79.542 1.00137.17 C +ATOM 5961 C LYS D 33 15.518 -17.825 79.023 1.00154.72 C +ATOM 5962 O LYS D 33 15.465 -16.596 79.050 1.00132.03 O +ATOM 5963 CB LYS D 33 13.414 -19.062 78.396 1.00132.83 C +ATOM 5964 CG LYS D 33 12.762 -20.422 78.573 1.00121.96 C +ATOM 5965 CD LYS D 33 11.724 -20.660 77.493 1.00129.75 C +ATOM 5966 CE LYS D 33 10.664 -21.633 77.971 1.00135.09 C +ATOM 5967 NZ LYS D 33 9.551 -21.749 76.994 1.00172.19 N +ATOM 5968 N ILE D 34 16.578 -18.494 78.571 1.00157.95 N +ATOM 5969 CA ILE D 34 17.777 -17.808 78.113 1.00130.46 C +ATOM 5970 C ILE D 34 17.808 -17.879 76.581 1.00136.95 C +ATOM 5971 O ILE D 34 17.337 -18.849 75.968 1.00163.75 O +ATOM 5972 CB ILE D 34 19.046 -18.385 78.797 1.00133.16 C +ATOM 5973 CG1 ILE D 34 19.017 -18.085 80.300 1.00133.30 C +ATOM 5974 CG2 ILE D 34 20.326 -17.787 78.234 1.00153.22 C +ATOM 5975 CD1 ILE D 34 18.986 -19.325 81.159 1.00147.34 C +ATOM 5976 N PHE D 35 18.238 -16.780 75.972 1.00123.93 N +ATOM 5977 CA PHE D 35 18.330 -16.661 74.524 1.00103.23 C +ATOM 5978 C PHE D 35 19.624 -17.300 74.037 1.00 99.34 C +ATOM 5979 O PHE D 35 20.711 -16.876 74.455 1.00133.51 O +ATOM 5980 CB PHE D 35 18.347 -15.181 74.148 1.00 95.84 C +ATOM 5981 CG PHE D 35 16.986 -14.561 74.025 1.00 75.56 C +ATOM 5982 CD1 PHE D 35 15.977 -15.199 73.312 1.00 74.18 C +ATOM 5983 CD2 PHE D 35 16.757 -13.284 74.514 1.00 66.49 C +ATOM 5984 CE1 PHE D 35 14.740 -14.597 73.137 1.00 71.24 C +ATOM 5985 CE2 PHE D 35 15.532 -12.673 74.329 1.00 69.46 C +ATOM 5986 CZ PHE D 35 14.514 -13.334 73.648 1.00 69.27 C +ATOM 5987 N VAL D 36 19.528 -18.229 73.087 1.00 69.43 N +ATOM 5988 CA VAL D 36 20.712 -18.926 72.631 1.00 88.98 C +ATOM 5989 C VAL D 36 20.839 -18.973 71.100 1.00127.15 C +ATOM 5990 O VAL D 36 19.853 -18.966 70.386 1.00150.49 O +ATOM 5991 CB VAL D 36 20.739 -20.348 73.192 1.00 77.92 C +ATOM 5992 CG1 VAL D 36 19.751 -21.228 72.448 1.00 75.44 C +ATOM 5993 CG2 VAL D 36 22.147 -20.909 73.105 1.00 85.81 C +ATOM 5994 N SER D 37 22.076 -19.026 70.611 1.00138.23 N +ATOM 5995 CA SER D 37 22.332 -19.092 69.183 1.00108.31 C +ATOM 5996 C SER D 37 23.139 -20.330 68.894 1.00109.65 C +ATOM 5997 O SER D 37 24.149 -20.596 69.553 1.00 79.83 O +ATOM 5998 CB SER D 37 23.148 -17.894 68.754 1.00126.26 C +ATOM 5999 OG SER D 37 22.372 -16.722 68.712 1.00158.29 O +ATOM 6000 N VAL D 38 22.731 -21.093 67.894 1.00103.00 N +ATOM 6001 CA VAL D 38 23.615 -22.150 67.394 1.00142.85 C +ATOM 6002 C VAL D 38 23.887 -21.902 65.918 1.00150.34 C +ATOM 6003 O VAL D 38 22.944 -21.942 65.113 1.00241.42 O +ATOM 6004 CB VAL D 38 23.009 -23.568 67.554 1.00147.37 C +ATOM 6005 CG1 VAL D 38 23.946 -24.614 66.962 1.00128.22 C +ATOM 6006 CG2 VAL D 38 22.725 -23.891 69.010 1.00158.35 C +ATOM 6007 N TYR D 39 25.167 -21.717 65.565 1.00103.20 N +ATOM 6008 CA TYR D 39 25.567 -21.459 64.186 1.00 83.00 C +ATOM 6009 C TYR D 39 25.853 -22.794 63.482 1.00 84.02 C +ATOM 6010 O TYR D 39 25.287 -23.082 62.412 1.00113.09 O +ATOM 6011 CB TYR D 39 26.774 -20.503 64.139 1.00 75.42 C +ATOM 6012 CG TYR D 39 26.389 -19.026 64.207 1.00 77.45 C +ATOM 6013 CD1 TYR D 39 26.010 -18.425 65.400 1.00 76.47 C +ATOM 6014 CD2 TYR D 39 26.386 -18.234 63.078 1.00 96.02 C +ATOM 6015 CE1 TYR D 39 25.595 -17.092 65.454 1.00 69.03 C +ATOM 6016 CE2 TYR D 39 25.991 -16.888 63.126 1.00106.50 C +ATOM 6017 CZ TYR D 39 25.580 -16.321 64.316 1.00 74.89 C +ATOM 6018 OH TYR D 39 25.184 -14.985 64.334 1.00 43.52 O +ATOM 6019 N ASN D 40 26.677 -23.642 64.086 1.00 73.97 N +ATOM 6020 CA ASN D 40 27.038 -24.908 63.449 1.00 75.00 C +ATOM 6021 C ASN D 40 27.774 -25.860 64.362 1.00 84.32 C +ATOM 6022 O ASN D 40 28.773 -25.487 65.005 1.00110.55 O +ATOM 6023 CB ASN D 40 27.912 -24.649 62.211 1.00 94.88 C +ATOM 6024 CG ASN D 40 27.955 -25.835 61.268 1.00106.85 C +ATOM 6025 OD1 ASN D 40 29.012 -26.421 61.037 1.00126.33 O +ATOM 6026 ND2 ASN D 40 26.803 -26.184 60.700 1.00125.64 N +ATOM 6027 N ILE D 41 27.354 -27.118 64.352 1.00 78.28 N +ATOM 6028 CA ILE D 41 28.135 -28.201 64.970 1.00 98.54 C +ATOM 6029 C ILE D 41 28.581 -29.215 63.907 1.00 80.08 C +ATOM 6030 O ILE D 41 27.741 -29.851 63.271 1.00 79.47 O +ATOM 6031 CB ILE D 41 27.320 -28.921 66.073 1.00103.19 C +ATOM 6032 CG1 ILE D 41 27.314 -28.121 67.375 1.00116.11 C +ATOM 6033 CG2 ILE D 41 27.953 -30.263 66.396 1.00105.96 C +ATOM 6034 CD1 ILE D 41 26.504 -26.835 67.350 1.00103.95 C +ATOM 6035 N GLN D 42 29.888 -29.361 63.715 1.00 80.05 N +ATOM 6036 CA GLN D 42 30.415 -30.106 62.560 1.00 98.75 C +ATOM 6037 C GLN D 42 30.635 -31.576 62.853 1.00 85.36 C +ATOM 6038 O GLN D 42 30.789 -31.974 64.000 1.00 73.97 O +ATOM 6039 CB GLN D 42 31.756 -29.532 62.095 1.00129.47 C +ATOM 6040 CG GLN D 42 31.683 -28.123 61.548 1.00147.59 C +ATOM 6041 CD GLN D 42 32.521 -27.152 62.358 1.00167.28 C +ATOM 6042 OE1 GLN D 42 33.717 -26.973 62.090 1.00239.81 O +ATOM 6043 NE2 GLN D 42 31.912 -26.533 63.368 1.00137.98 N +ATOM 6044 N ASP D 43 30.672 -32.367 61.788 1.00 88.08 N +ATOM 6045 CA ASP D 43 31.046 -33.781 61.861 1.00 86.09 C +ATOM 6046 C ASP D 43 32.534 -33.918 61.849 1.00 61.05 C +ATOM 6047 O ASP D 43 33.121 -34.412 60.872 1.00 42.56 O +ATOM 6048 CB ASP D 43 30.448 -34.550 60.665 1.00140.19 C +ATOM 6049 CG ASP D 43 30.637 -36.067 60.782 1.00153.98 C +ATOM 6050 OD1 ASP D 43 30.309 -36.621 61.851 1.00195.14 O +ATOM 6051 OD2 ASP D 43 31.093 -36.714 59.819 1.00125.89 O +ATOM 6052 N GLU D 44 33.158 -33.404 62.907 1.00 62.23 N +ATOM 6053 CA GLU D 44 34.624 -33.371 63.003 1.00 76.96 C +ATOM 6054 C GLU D 44 35.232 -34.807 63.136 1.00 79.72 C +ATOM 6055 O GLU D 44 36.429 -34.951 63.479 1.00 75.65 O +ATOM 6056 CB GLU D 44 35.094 -32.440 64.167 1.00 69.97 C +ATOM 6057 CG GLU D 44 35.279 -30.965 63.791 1.00102.38 C +ATOM 6058 CD GLU D 44 35.699 -30.055 64.963 1.00126.55 C +ATOM 6059 OE1 GLU D 44 36.619 -30.394 65.744 1.00132.23 O +ATOM 6060 OE2 GLU D 44 35.164 -28.931 65.067 1.00152.93 O +ATOM 6061 N THR D 45 34.431 -35.833 62.810 1.00 77.74 N +ATOM 6062 CA THR D 45 34.755 -37.226 63.138 1.00 73.60 C +ATOM 6063 C THR D 45 35.729 -37.870 62.173 1.00 77.65 C +ATOM 6064 O THR D 45 36.685 -38.516 62.608 1.00 93.59 O +ATOM 6065 CB THR D 45 33.511 -38.114 63.258 1.00 57.97 C +ATOM 6066 OG1 THR D 45 33.884 -39.351 63.864 1.00 96.46 O +ATOM 6067 CG2 THR D 45 32.895 -38.391 61.928 1.00 50.69 C +ATOM 6068 N GLY D 46 35.585 -37.572 60.892 1.00 93.18 N +ATOM 6069 CA GLY D 46 36.630 -37.920 59.901 1.00120.37 C +ATOM 6070 C GLY D 46 36.394 -39.301 59.328 1.00112.09 C +ATOM 6071 O GLY D 46 37.269 -39.961 58.753 1.00120.62 O +ATOM 6072 N GLN D 47 35.179 -39.752 59.447 1.00 93.25 N +ATOM 6073 CA GLN D 47 34.987 -41.125 59.278 1.00101.07 C +ATOM 6074 C GLN D 47 33.850 -41.417 58.323 1.00137.79 C +ATOM 6075 O GLN D 47 32.782 -40.780 58.358 1.00179.93 O +ATOM 6076 CB GLN D 47 34.757 -41.718 60.636 1.00 94.55 C +ATOM 6077 CG GLN D 47 35.999 -41.699 61.498 1.00 77.24 C +ATOM 6078 CD GLN D 47 37.189 -42.267 60.779 1.00 84.61 C +ATOM 6079 OE1 GLN D 47 37.304 -43.475 60.588 1.00 70.29 O +ATOM 6080 NE2 GLN D 47 38.117 -41.415 60.437 1.00111.13 N +ATOM 6081 N PHE D 48 34.073 -42.442 57.512 1.00142.25 N +ATOM 6082 CA PHE D 48 33.082 -42.918 56.566 1.00104.41 C +ATOM 6083 C PHE D 48 32.803 -44.399 56.784 1.00102.29 C +ATOM 6084 O PHE D 48 33.568 -45.131 57.433 1.00 97.84 O +ATOM 6085 CB PHE D 48 33.590 -42.689 55.132 1.00108.77 C +ATOM 6086 CG PHE D 48 33.739 -41.265 54.778 1.00 94.89 C +ATOM 6087 CD1 PHE D 48 34.816 -40.544 55.248 1.00 77.09 C +ATOM 6088 CD2 PHE D 48 32.738 -40.623 54.085 1.00 97.87 C +ATOM 6089 CE1 PHE D 48 34.877 -39.200 55.052 1.00 79.46 C +ATOM 6090 CE2 PHE D 48 32.778 -39.271 53.900 1.00 93.24 C +ATOM 6091 CZ PHE D 48 33.867 -38.563 54.353 1.00 95.84 C +ATOM 6092 N LYS D 49 31.745 -44.860 56.138 1.00114.89 N +ATOM 6093 CA LYS D 49 31.333 -46.249 56.238 1.00106.09 C +ATOM 6094 C LYS D 49 32.237 -47.113 55.370 1.00 99.61 C +ATOM 6095 O LYS D 49 32.679 -46.693 54.297 1.00 81.08 O +ATOM 6096 CB LYS D 49 29.848 -46.417 55.856 1.00 95.84 C +ATOM 6097 CG LYS D 49 28.916 -45.705 56.832 1.00 99.14 C +ATOM 6098 CD LYS D 49 27.422 -45.939 56.666 1.00 97.55 C +ATOM 6099 CE LYS D 49 26.716 -45.238 57.835 1.00100.80 C +ATOM 6100 NZ LYS D 49 25.229 -45.370 57.862 1.00 96.50 N +ATOM 6101 N PRO D 50 32.511 -48.329 55.847 1.00110.58 N +ATOM 6102 CA PRO D 50 33.326 -49.270 55.106 1.00110.68 C +ATOM 6103 C PRO D 50 32.566 -49.930 53.956 1.00113.59 C +ATOM 6104 O PRO D 50 31.313 -49.879 53.901 1.00154.88 O +ATOM 6105 CB PRO D 50 33.726 -50.291 56.182 1.00119.55 C +ATOM 6106 CG PRO D 50 32.607 -50.259 57.172 1.00114.67 C +ATOM 6107 CD PRO D 50 32.087 -48.854 57.164 1.00114.20 C +ATOM 6108 N TYR D 51 33.308 -50.592 53.077 1.00108.70 N +ATOM 6109 CA TYR D 51 32.694 -51.481 52.112 1.00109.67 C +ATOM 6110 C TYR D 51 31.659 -52.395 52.802 1.00130.36 C +ATOM 6111 O TYR D 51 31.937 -52.962 53.859 1.00123.14 O +ATOM 6112 CB TYR D 51 33.747 -52.339 51.407 1.00 82.74 C +ATOM 6113 CG TYR D 51 33.208 -52.970 50.171 1.00107.79 C +ATOM 6114 CD1 TYR D 51 33.200 -52.267 48.978 1.00151.45 C +ATOM 6115 CD2 TYR D 51 32.633 -54.251 50.182 1.00138.05 C +ATOM 6116 CE1 TYR D 51 32.650 -52.810 47.823 1.00175.78 C +ATOM 6117 CE2 TYR D 51 32.116 -54.829 49.007 1.00141.89 C +ATOM 6118 CZ TYR D 51 32.104 -54.078 47.839 1.00155.66 C +ATOM 6119 OH TYR D 51 31.604 -54.557 46.652 1.00142.27 O +ATOM 6120 N PRO D 52 30.451 -52.549 52.210 1.00148.35 N +ATOM 6121 CA PRO D 52 30.019 -52.108 50.874 1.00138.89 C +ATOM 6122 C PRO D 52 29.310 -50.758 50.773 1.00 82.70 C +ATOM 6123 O PRO D 52 28.649 -50.515 49.768 1.00 96.06 O +ATOM 6124 CB PRO D 52 29.042 -53.218 50.462 1.00141.09 C +ATOM 6125 CG PRO D 52 28.395 -53.616 51.752 1.00133.01 C +ATOM 6126 CD PRO D 52 29.467 -53.478 52.809 1.00137.37 C +ATOM 6127 N ALA D 53 29.392 -49.924 51.795 1.00 53.19 N +ATOM 6128 CA ALA D 53 28.776 -48.611 51.698 1.00 68.24 C +ATOM 6129 C ALA D 53 29.372 -47.824 50.543 1.00 79.50 C +ATOM 6130 O ALA D 53 30.526 -48.098 50.102 1.00108.94 O +ATOM 6131 CB ALA D 53 28.940 -47.841 53.003 1.00 90.27 C +ATOM 6132 N SER D 54 28.682 -46.756 50.146 1.00 73.33 N +ATOM 6133 CA SER D 54 29.339 -45.798 49.283 1.00108.72 C +ATOM 6134 C SER D 54 30.580 -45.221 49.989 1.00118.89 C +ATOM 6135 O SER D 54 30.583 -44.950 51.188 1.00 76.02 O +ATOM 6136 CB SER D 54 28.407 -44.672 48.851 1.00130.78 C +ATOM 6137 OG SER D 54 29.124 -43.513 48.399 1.00205.79 O +ATOM 6138 N ASN D 55 31.653 -45.064 49.213 1.00 98.21 N +ATOM 6139 CA ASN D 55 32.849 -44.417 49.685 1.00 74.50 C +ATOM 6140 C ASN D 55 32.540 -43.093 50.432 1.00 77.55 C +ATOM 6141 O ASN D 55 33.286 -42.672 51.344 1.00 79.80 O +ATOM 6142 CB ASN D 55 33.752 -44.130 48.500 1.00 69.33 C +ATOM 6143 CG ASN D 55 35.170 -43.841 48.918 1.00 91.95 C +ATOM 6144 OD1 ASN D 55 35.604 -44.164 50.013 1.00126.13 O +ATOM 6145 ND2 ASN D 55 35.906 -43.268 48.018 1.00101.94 N +ATOM 6146 N PHE D 56 31.440 -42.436 50.034 1.00 60.50 N +ATOM 6147 CA PHE D 56 31.113 -41.083 50.484 1.00 55.31 C +ATOM 6148 C PHE D 56 30.128 -41.108 51.620 1.00 58.97 C +ATOM 6149 O PHE D 56 29.698 -40.032 52.085 1.00 68.11 O +ATOM 6150 CB PHE D 56 30.482 -40.253 49.383 1.00 51.13 C +ATOM 6151 CG PHE D 56 31.350 -40.061 48.219 1.00 69.26 C +ATOM 6152 CD1 PHE D 56 32.569 -39.404 48.317 1.00 85.95 C +ATOM 6153 CD2 PHE D 56 30.991 -40.599 47.007 1.00116.79 C +ATOM 6154 CE1 PHE D 56 33.417 -39.279 47.215 1.00107.14 C +ATOM 6155 CE2 PHE D 56 31.815 -40.443 45.894 1.00158.41 C +ATOM 6156 CZ PHE D 56 33.041 -39.793 46.003 1.00123.68 C +ATOM 6157 N SER D 57 29.679 -42.288 52.031 1.00 48.60 N +ATOM 6158 CA SER D 57 28.729 -42.323 53.121 1.00 62.10 C +ATOM 6159 C SER D 57 29.481 -42.020 54.435 1.00 58.90 C +ATOM 6160 O SER D 57 30.308 -42.804 54.892 1.00 62.31 O +ATOM 6161 CB SER D 57 27.993 -43.668 53.154 1.00 81.25 C +ATOM 6162 OG SER D 57 27.033 -43.726 52.118 1.00108.01 O +ATOM 6163 N THR D 58 29.128 -40.921 55.076 1.00 58.18 N +ATOM 6164 CA THR D 58 29.711 -40.583 56.354 1.00 71.16 C +ATOM 6165 C THR D 58 29.263 -41.547 57.427 1.00 89.90 C +ATOM 6166 O THR D 58 28.137 -42.046 57.456 1.00114.81 O +ATOM 6167 CB THR D 58 29.295 -39.171 56.787 1.00 68.01 C +ATOM 6168 OG1 THR D 58 27.859 -39.110 56.936 1.00 41.42 O +ATOM 6169 CG2 THR D 58 29.712 -38.221 55.742 1.00 79.55 C +ATOM 6170 N ALA D 59 30.091 -41.724 58.414 1.00 97.61 N +ATOM 6171 CA ALA D 59 29.679 -42.614 59.474 1.00105.18 C +ATOM 6172 C ALA D 59 28.585 -42.019 60.386 1.00 75.02 C +ATOM 6173 O ALA D 59 27.953 -42.728 61.141 1.00 67.75 O +ATOM 6174 CB ALA D 59 30.900 -43.040 60.265 1.00121.34 C +ATOM 6175 N VAL D 60 28.476 -40.700 60.390 1.00 69.00 N +ATOM 6176 CA VAL D 60 27.675 -39.985 61.363 1.00 61.58 C +ATOM 6177 C VAL D 60 26.876 -38.958 60.620 1.00 68.06 C +ATOM 6178 O VAL D 60 27.377 -38.320 59.663 1.00 76.59 O +ATOM 6179 CB VAL D 60 28.575 -39.233 62.360 1.00 91.28 C +ATOM 6180 CG1 VAL D 60 27.758 -38.419 63.362 1.00 84.49 C +ATOM 6181 CG2 VAL D 60 29.496 -40.213 63.095 1.00133.91 C +ATOM 6182 N PRO D 61 25.629 -38.765 61.033 1.00 77.73 N +ATOM 6183 CA PRO D 61 24.789 -37.811 60.285 1.00100.88 C +ATOM 6184 C PRO D 61 25.240 -36.371 60.465 1.00 83.43 C +ATOM 6185 O PRO D 61 25.769 -36.029 61.532 1.00 70.78 O +ATOM 6186 CB PRO D 61 23.397 -38.004 60.902 1.00117.18 C +ATOM 6187 CG PRO D 61 23.652 -38.642 62.227 1.00107.73 C +ATOM 6188 CD PRO D 61 24.846 -39.529 62.008 1.00 90.09 C +ATOM 6189 N GLN D 62 25.033 -35.561 59.427 1.00 71.93 N +ATOM 6190 CA GLN D 62 25.609 -34.222 59.378 1.00 79.80 C +ATOM 6191 C GLN D 62 24.619 -33.274 59.955 1.00 65.72 C +ATOM 6192 O GLN D 62 24.518 -32.142 59.499 1.00118.61 O +ATOM 6193 CB GLN D 62 25.947 -33.791 57.919 1.00 82.66 C +ATOM 6194 CG GLN D 62 26.830 -34.769 57.152 1.00 85.02 C +ATOM 6195 CD GLN D 62 28.155 -35.021 57.857 1.00 74.48 C +ATOM 6196 OE1 GLN D 62 29.056 -34.200 57.801 1.00 53.72 O +ATOM 6197 NE2 GLN D 62 28.261 -36.153 58.550 1.00 67.90 N +ATOM 6198 N SER D 63 23.892 -33.718 60.959 1.00 55.95 N +ATOM 6199 CA SER D 63 22.663 -33.051 61.355 1.00 80.72 C +ATOM 6200 C SER D 63 22.697 -32.544 62.798 1.00 76.45 C +ATOM 6201 O SER D 63 21.678 -32.151 63.366 1.00 97.89 O +ATOM 6202 CB SER D 63 21.462 -33.999 61.103 1.00 98.55 C +ATOM 6203 OG SER D 63 21.519 -35.187 61.869 1.00116.34 O +ATOM 6204 N ALA D 64 23.872 -32.604 63.394 1.00 70.63 N +ATOM 6205 CA ALA D 64 24.014 -32.399 64.825 1.00 79.42 C +ATOM 6206 C ALA D 64 23.476 -31.038 65.254 1.00 70.68 C +ATOM 6207 O ALA D 64 22.910 -30.870 66.344 1.00 55.06 O +ATOM 6208 CB ALA D 64 25.487 -32.560 65.196 1.00 88.35 C +ATOM 6209 N THR D 65 23.693 -30.058 64.388 1.00 87.24 N +ATOM 6210 CA THR D 65 23.314 -28.679 64.663 1.00110.33 C +ATOM 6211 C THR D 65 21.844 -28.603 65.044 1.00 98.12 C +ATOM 6212 O THR D 65 21.470 -27.950 66.024 1.00 79.33 O +ATOM 6213 CB THR D 65 23.544 -27.821 63.408 1.00 99.48 C +ATOM 6214 OG1 THR D 65 24.780 -28.222 62.808 1.00 96.74 O +ATOM 6215 CG2 THR D 65 23.581 -26.335 63.769 1.00104.15 C +ATOM 6216 N ALA D 66 21.017 -29.243 64.234 1.00104.52 N +ATOM 6217 CA ALA D 66 19.584 -29.124 64.396 1.00113.08 C +ATOM 6218 C ALA D 66 19.141 -29.896 65.623 1.00 79.58 C +ATOM 6219 O ALA D 66 18.217 -29.475 66.330 1.00 70.47 O +ATOM 6220 CB ALA D 66 18.876 -29.610 63.140 1.00116.74 C +ATOM 6221 N MET D 67 19.855 -30.978 65.905 1.00 87.09 N +ATOM 6222 CA MET D 67 19.575 -31.785 67.086 1.00118.63 C +ATOM 6223 C MET D 67 19.863 -30.983 68.354 1.00123.77 C +ATOM 6224 O MET D 67 19.073 -31.009 69.321 1.00131.37 O +ATOM 6225 CB MET D 67 20.419 -33.066 67.099 1.00106.25 C +ATOM 6226 CG MET D 67 20.042 -34.116 66.065 1.00102.18 C +ATOM 6227 SD MET D 67 21.293 -35.414 65.951 1.00 80.37 S +ATOM 6228 CE MET D 67 20.516 -36.571 64.835 1.00109.15 C +ATOM 6229 N LEU D 68 20.957 -30.231 68.326 1.00 96.75 N +ATOM 6230 CA LEU D 68 21.312 -29.418 69.472 1.00 98.67 C +ATOM 6231 C LEU D 68 20.305 -28.316 69.689 1.00 94.95 C +ATOM 6232 O LEU D 68 19.889 -28.074 70.829 1.00113.52 O +ATOM 6233 CB LEU D 68 22.685 -28.785 69.315 1.00100.39 C +ATOM 6234 CG LEU D 68 22.995 -27.727 70.403 1.00 78.53 C +ATOM 6235 CD1 LEU D 68 23.124 -28.360 71.770 1.00 68.46 C +ATOM 6236 CD2 LEU D 68 24.258 -26.956 70.077 1.00 90.10 C +ATOM 6237 N VAL D 69 19.908 -27.641 68.613 1.00 99.84 N +ATOM 6238 CA VAL D 69 18.902 -26.571 68.729 1.00143.13 C +ATOM 6239 C VAL D 69 17.578 -27.112 69.296 1.00134.45 C +ATOM 6240 O VAL D 69 16.987 -26.530 70.209 1.00132.25 O +ATOM 6241 CB VAL D 69 18.592 -25.900 67.376 1.00166.86 C +ATOM 6242 CG1 VAL D 69 17.432 -24.928 67.535 1.00180.46 C +ATOM 6243 CG2 VAL D 69 19.803 -25.165 66.823 1.00156.11 C +ATOM 6244 N THR D 70 17.166 -28.271 68.799 1.00128.82 N +ATOM 6245 CA THR D 70 15.970 -28.940 69.295 1.00131.31 C +ATOM 6246 C THR D 70 16.082 -29.320 70.774 1.00131.58 C +ATOM 6247 O THR D 70 15.159 -29.080 71.560 1.00114.09 O +ATOM 6248 CB THR D 70 15.673 -30.198 68.462 1.00151.70 C +ATOM 6249 OG1 THR D 70 15.618 -29.819 67.079 1.00197.59 O +ATOM 6250 CG2 THR D 70 14.343 -30.844 68.894 1.00141.53 C +ATOM 6251 N ALA D 71 17.226 -29.887 71.160 1.00120.17 N +ATOM 6252 CA ALA D 71 17.461 -30.234 72.561 1.00132.88 C +ATOM 6253 C ALA D 71 17.434 -28.986 73.458 1.00141.16 C +ATOM 6254 O ALA D 71 16.848 -28.991 74.552 1.00156.40 O +ATOM 6255 CB ALA D 71 18.785 -30.972 72.713 1.00111.97 C +ATOM 6256 N LEU D 72 18.062 -27.913 72.985 1.00124.18 N +ATOM 6257 CA LEU D 72 18.049 -26.641 73.715 1.00103.80 C +ATOM 6258 C LEU D 72 16.621 -26.117 73.905 1.00120.90 C +ATOM 6259 O LEU D 72 16.363 -25.374 74.852 1.00111.56 O +ATOM 6260 CB LEU D 72 18.898 -25.584 73.002 1.00 74.15 C +ATOM 6261 CG LEU D 72 20.387 -25.868 72.978 1.00 64.57 C +ATOM 6262 CD1 LEU D 72 21.028 -25.019 71.922 1.00 65.87 C +ATOM 6263 CD2 LEU D 72 21.026 -25.589 74.312 1.00 87.90 C +ATOM 6264 N LYS D 73 15.711 -26.480 72.993 1.00115.20 N +ATOM 6265 CA LYS D 73 14.326 -26.012 73.083 1.00103.87 C +ATOM 6266 C LYS D 73 13.512 -26.884 73.988 1.00109.45 C +ATOM 6267 O LYS D 73 12.790 -26.386 74.848 1.00117.08 O +ATOM 6268 CB LYS D 73 13.658 -25.964 71.723 1.00 99.32 C +ATOM 6269 CG LYS D 73 12.330 -25.213 71.736 1.00123.47 C +ATOM 6270 CD LYS D 73 11.682 -25.187 70.349 1.00181.20 C +ATOM 6271 CE LYS D 73 10.164 -25.092 70.420 1.00205.25 C +ATOM 6272 NZ LYS D 73 9.631 -23.806 69.883 1.00226.97 N +ATOM 6273 N ASP D 74 13.659 -28.191 73.822 1.00124.92 N +ATOM 6274 CA ASP D 74 12.903 -29.140 74.628 1.00155.20 C +ATOM 6275 C ASP D 74 13.164 -28.983 76.130 1.00147.12 C +ATOM 6276 O ASP D 74 12.287 -29.289 76.954 1.00172.68 O +ATOM 6277 CB ASP D 74 13.212 -30.578 74.189 1.00164.73 C +ATOM 6278 CG ASP D 74 12.718 -30.882 72.768 1.00147.93 C +ATOM 6279 OD1 ASP D 74 11.676 -30.322 72.338 1.00131.12 O +ATOM 6280 OD2 ASP D 74 13.303 -31.800 72.151 1.00 98.02 O +ATOM 6281 N SER D 75 14.363 -28.516 76.480 1.00128.32 N +ATOM 6282 CA SER D 75 14.772 -28.377 77.884 1.00132.34 C +ATOM 6283 C SER D 75 13.934 -27.340 78.640 1.00126.52 C +ATOM 6284 O SER D 75 13.831 -27.409 79.873 1.00111.25 O +ATOM 6285 CB SER D 75 16.253 -27.986 77.983 1.00127.82 C +ATOM 6286 OG SER D 75 16.417 -26.582 77.883 1.00 93.10 O +ATOM 6287 N ARG D 76 13.368 -26.388 77.894 1.00107.34 N +ATOM 6288 CA ARG D 76 12.581 -25.285 78.443 1.00117.63 C +ATOM 6289 C ARG D 76 13.423 -24.392 79.327 1.00112.41 C +ATOM 6290 O ARG D 76 12.977 -23.895 80.354 1.00 95.99 O +ATOM 6291 CB ARG D 76 11.371 -25.801 79.203 1.00148.72 C +ATOM 6292 CG ARG D 76 10.384 -26.598 78.361 1.00173.84 C +ATOM 6293 CD ARG D 76 9.193 -27.033 79.213 1.00205.06 C +ATOM 6294 NE ARG D 76 9.575 -28.049 80.205 1.00198.15 N +ATOM 6295 CZ ARG D 76 9.928 -27.802 81.468 1.00179.06 C +ATOM 6296 NH1 ARG D 76 9.953 -26.558 81.947 1.00204.49 N +ATOM 6297 NH2 ARG D 76 10.267 -28.805 82.253 1.00150.89 N +ATOM 6298 N TRP D 77 14.682 -24.261 78.942 1.00127.08 N +ATOM 6299 CA TRP D 77 15.594 -23.315 79.563 1.00121.25 C +ATOM 6300 C TRP D 77 15.972 -22.214 78.568 1.00136.11 C +ATOM 6301 O TRP D 77 16.211 -21.065 78.946 1.00106.31 O +ATOM 6302 CB TRP D 77 16.859 -24.051 80.031 1.00120.99 C +ATOM 6303 CG TRP D 77 16.807 -24.517 81.443 1.00122.11 C +ATOM 6304 CD1 TRP D 77 16.135 -25.593 81.918 1.00126.84 C +ATOM 6305 CD2 TRP D 77 17.482 -23.938 82.563 1.00116.87 C +ATOM 6306 NE1 TRP D 77 16.330 -25.711 83.265 1.00120.15 N +ATOM 6307 CE2 TRP D 77 17.150 -24.698 83.684 1.00116.32 C +ATOM 6308 CE3 TRP D 77 18.325 -22.840 82.723 1.00129.56 C +ATOM 6309 CZ2 TRP D 77 17.618 -24.393 84.953 1.00137.46 C +ATOM 6310 CZ3 TRP D 77 18.799 -22.546 83.983 1.00132.74 C +ATOM 6311 CH2 TRP D 77 18.447 -23.321 85.082 1.00131.47 C +ATOM 6312 N PHE D 78 16.069 -22.595 77.292 1.00160.95 N +ATOM 6313 CA PHE D 78 16.571 -21.721 76.226 1.00128.92 C +ATOM 6314 C PHE D 78 15.520 -21.472 75.123 1.00115.92 C +ATOM 6315 O PHE D 78 14.795 -22.393 74.730 1.00142.18 O +ATOM 6316 CB PHE D 78 17.794 -22.362 75.571 1.00104.13 C +ATOM 6317 CG PHE D 78 18.880 -22.708 76.524 1.00 82.80 C +ATOM 6318 CD1 PHE D 78 19.684 -21.725 77.078 1.00 84.81 C +ATOM 6319 CD2 PHE D 78 19.099 -24.016 76.862 1.00 91.70 C +ATOM 6320 CE1 PHE D 78 20.695 -22.045 77.962 1.00 93.19 C +ATOM 6321 CE2 PHE D 78 20.120 -24.352 77.731 1.00117.57 C +ATOM 6322 CZ PHE D 78 20.928 -23.364 78.274 1.00104.44 C +ATOM 6323 N ILE D 79 15.490 -20.245 74.607 1.00 78.76 N +ATOM 6324 CA ILE D 79 14.879 -19.939 73.339 1.00 77.71 C +ATOM 6325 C ILE D 79 15.991 -19.952 72.299 1.00 95.19 C +ATOM 6326 O ILE D 79 17.000 -19.247 72.442 1.00119.73 O +ATOM 6327 CB ILE D 79 14.275 -18.541 73.364 1.00 98.43 C +ATOM 6328 CG1 ILE D 79 13.418 -18.344 74.612 1.00114.55 C +ATOM 6329 CG2 ILE D 79 13.439 -18.290 72.110 1.00118.01 C +ATOM 6330 CD1 ILE D 79 13.238 -16.890 75.008 1.00136.53 C +ATOM 6331 N PRO D 80 15.840 -20.775 71.255 1.00111.64 N +ATOM 6332 CA PRO D 80 16.880 -20.734 70.242 1.00119.81 C +ATOM 6333 C PRO D 80 16.556 -19.726 69.156 1.00133.40 C +ATOM 6334 O PRO D 80 15.418 -19.649 68.705 1.00 94.18 O +ATOM 6335 CB PRO D 80 16.879 -22.149 69.675 1.00107.15 C +ATOM 6336 CG PRO D 80 16.274 -22.969 70.740 1.00125.10 C +ATOM 6337 CD PRO D 80 15.186 -22.084 71.277 1.00124.88 C +ATOM 6338 N LEU D 81 17.545 -18.916 68.807 1.00136.40 N +ATOM 6339 CA LEU D 81 17.416 -17.988 67.721 1.00110.76 C +ATOM 6340 C LEU D 81 17.994 -18.629 66.474 1.00103.19 C +ATOM 6341 O LEU D 81 18.986 -19.384 66.548 1.00 97.38 O +ATOM 6342 CB LEU D 81 18.140 -16.708 68.067 1.00116.14 C +ATOM 6343 CG LEU D 81 17.641 -16.127 69.382 1.00130.42 C +ATOM 6344 CD1 LEU D 81 18.479 -14.920 69.721 1.00119.14 C +ATOM 6345 CD2 LEU D 81 16.173 -15.746 69.272 1.00137.31 C +ATOM 6346 N GLU D 82 17.305 -18.396 65.360 1.00 75.93 N +ATOM 6347 CA GLU D 82 17.630 -19.053 64.095 1.00 68.61 C +ATOM 6348 C GLU D 82 18.821 -18.361 63.443 1.00 63.64 C +ATOM 6349 O GLU D 82 18.716 -17.228 62.951 1.00 63.34 O +ATOM 6350 CB GLU D 82 16.413 -19.074 63.128 1.00 73.42 C +ATOM 6351 CG GLU D 82 16.677 -19.700 61.751 1.00 71.15 C +ATOM 6352 CD GLU D 82 16.921 -21.221 61.773 1.00 91.26 C +ATOM 6353 OE1 GLU D 82 17.718 -21.761 62.627 1.00 84.62 O +ATOM 6354 OE2 GLU D 82 16.302 -21.909 60.917 1.00 84.43 O +ATOM 6355 N ARG D 83 19.926 -19.084 63.394 1.00 63.03 N +ATOM 6356 CA ARG D 83 21.125 -18.636 62.701 1.00 61.41 C +ATOM 6357 C ARG D 83 21.611 -19.673 61.672 1.00 86.64 C +ATOM 6358 O ARG D 83 22.357 -19.331 60.770 1.00100.37 O +ATOM 6359 CB ARG D 83 22.239 -18.338 63.706 1.00 63.68 C +ATOM 6360 CG ARG D 83 21.860 -17.320 64.767 1.00 67.35 C +ATOM 6361 CD ARG D 83 21.703 -15.928 64.207 1.00 70.05 C +ATOM 6362 NE ARG D 83 21.587 -14.955 65.300 1.00 83.17 N +ATOM 6363 CZ ARG D 83 20.455 -14.379 65.722 1.00 83.21 C +ATOM 6364 NH1 ARG D 83 19.290 -14.636 65.114 1.00 79.77 N +ATOM 6365 NH2 ARG D 83 20.494 -13.552 66.765 1.00 69.74 N +ATOM 6366 N GLN D 84 21.196 -20.939 61.774 1.00117.59 N +ATOM 6367 CA GLN D 84 21.622 -21.932 60.766 1.00109.63 C +ATOM 6368 C GLN D 84 21.172 -21.491 59.367 1.00111.92 C +ATOM 6369 O GLN D 84 21.926 -21.556 58.425 1.00170.27 O +ATOM 6370 CB GLN D 84 21.118 -23.354 61.078 1.00110.61 C +ATOM 6371 CG GLN D 84 22.046 -24.469 60.597 1.00103.10 C +ATOM 6372 CD GLN D 84 21.496 -25.873 60.850 1.00119.10 C +ATOM 6373 OE1 GLN D 84 20.794 -26.110 61.825 1.00114.93 O +ATOM 6374 NE2 GLN D 84 21.746 -26.790 59.908 1.00134.39 N +ATOM 6375 N GLY D 85 19.970 -20.963 59.236 1.00101.41 N +ATOM 6376 CA GLY D 85 19.545 -20.474 57.927 1.00 86.22 C +ATOM 6377 C GLY D 85 19.479 -18.953 57.813 1.00 82.53 C +ATOM 6378 O GLY D 85 18.488 -18.410 57.305 1.00112.64 O +ATOM 6379 N LEU D 86 20.429 -18.249 58.418 1.00 55.08 N +ATOM 6380 CA LEU D 86 20.234 -16.826 58.716 1.00 64.51 C +ATOM 6381 C LEU D 86 19.976 -16.116 57.419 1.00 51.93 C +ATOM 6382 O LEU D 86 19.331 -15.046 57.393 1.00 62.58 O +ATOM 6383 CB LEU D 86 21.464 -16.247 59.469 1.00101.69 C +ATOM 6384 CG LEU D 86 21.642 -14.722 59.679 1.00108.57 C +ATOM 6385 CD1 LEU D 86 20.482 -14.092 60.441 1.00 94.41 C +ATOM 6386 CD2 LEU D 86 22.977 -14.433 60.392 1.00 83.99 C +ATOM 6387 N GLN D 87 20.587 -16.634 56.360 1.00 46.13 N +ATOM 6388 CA GLN D 87 20.656 -15.869 55.124 1.00 76.82 C +ATOM 6389 C GLN D 87 19.221 -15.717 54.592 1.00 92.54 C +ATOM 6390 O GLN D 87 18.826 -14.626 54.099 1.00 88.59 O +ATOM 6391 CB GLN D 87 21.606 -16.561 54.126 1.00 82.53 C +ATOM 6392 CG GLN D 87 22.308 -15.587 53.173 1.00104.57 C +ATOM 6393 CD GLN D 87 22.822 -14.300 53.851 1.00112.36 C +ATOM 6394 OE1 GLN D 87 23.632 -14.350 54.775 1.00 80.96 O +ATOM 6395 NE2 GLN D 87 22.380 -13.142 53.355 1.00112.63 N +ATOM 6396 N ASN D 88 18.434 -16.791 54.743 1.00 75.77 N +ATOM 6397 CA ASN D 88 17.057 -16.822 54.232 1.00 57.07 C +ATOM 6398 C ASN D 88 16.190 -15.899 55.039 1.00 54.80 C +ATOM 6399 O ASN D 88 15.277 -15.234 54.507 1.00 58.04 O +ATOM 6400 CB ASN D 88 16.470 -18.212 54.325 1.00 45.72 C +ATOM 6401 CG ASN D 88 17.210 -19.230 53.491 1.00 51.29 C +ATOM 6402 OD1 ASN D 88 17.777 -18.901 52.456 1.00 57.60 O +ATOM 6403 ND2 ASN D 88 17.340 -20.436 54.020 1.00 66.20 N +ATOM 6404 N LEU D 89 16.511 -15.828 56.320 1.00 46.98 N +ATOM 6405 CA LEU D 89 15.778 -14.973 57.229 1.00 58.19 C +ATOM 6406 C LEU D 89 15.933 -13.512 56.786 1.00 64.81 C +ATOM 6407 O LEU D 89 14.973 -12.737 56.724 1.00 65.14 O +ATOM 6408 CB LEU D 89 16.315 -15.218 58.648 1.00 56.97 C +ATOM 6409 CG LEU D 89 15.374 -15.063 59.820 1.00 70.15 C +ATOM 6410 CD1 LEU D 89 15.808 -13.929 60.696 1.00 69.39 C +ATOM 6411 CD2 LEU D 89 13.928 -14.832 59.360 1.00104.00 C +ATOM 6412 N LEU D 90 17.163 -13.147 56.444 1.00 86.10 N +ATOM 6413 CA LEU D 90 17.486 -11.755 56.083 1.00 78.97 C +ATOM 6414 C LEU D 90 16.913 -11.418 54.734 1.00 78.86 C +ATOM 6415 O LEU D 90 16.514 -10.276 54.475 1.00 86.40 O +ATOM 6416 CB LEU D 90 18.992 -11.558 56.050 1.00101.80 C +ATOM 6417 CG LEU D 90 19.710 -11.804 57.385 1.00110.47 C +ATOM 6418 CD1 LEU D 90 21.192 -12.043 57.130 1.00 84.64 C +ATOM 6419 CD2 LEU D 90 19.459 -10.615 58.307 1.00117.27 C +ATOM 6420 N ASN D 91 16.812 -12.441 53.886 1.00 92.57 N +ATOM 6421 CA ASN D 91 16.207 -12.289 52.574 1.00101.51 C +ATOM 6422 C ASN D 91 14.694 -12.004 52.677 1.00 93.06 C +ATOM 6423 O ASN D 91 14.182 -11.066 52.052 1.00 54.23 O +ATOM 6424 CB ASN D 91 16.455 -13.562 51.766 1.00 97.79 C +ATOM 6425 CG ASN D 91 17.347 -13.373 50.579 1.00113.76 C +ATOM 6426 OD1 ASN D 91 18.063 -12.377 50.437 1.00103.91 O +ATOM 6427 ND2 ASN D 91 17.255 -14.332 49.661 1.00142.62 N +ATOM 6428 N GLU D 92 13.985 -12.803 53.473 1.00 88.92 N +ATOM 6429 CA GLU D 92 12.553 -12.572 53.658 1.00 96.06 C +ATOM 6430 C GLU D 92 12.319 -11.163 54.182 1.00 75.25 C +ATOM 6431 O GLU D 92 11.315 -10.527 53.891 1.00 62.95 O +ATOM 6432 CB GLU D 92 11.935 -13.638 54.593 1.00107.51 C +ATOM 6433 CG GLU D 92 11.323 -14.839 53.876 1.00101.31 C +ATOM 6434 CD GLU D 92 10.287 -14.464 52.798 1.00 77.03 C +ATOM 6435 OE1 GLU D 92 9.291 -13.766 53.072 1.00 42.48 O +ATOM 6436 OE2 GLU D 92 10.503 -14.864 51.624 1.00 86.13 O +ATOM 6437 N ARG D 93 13.211 -10.724 55.052 1.00 66.02 N +ATOM 6438 CA ARG D 93 13.068 -9.420 55.652 1.00 72.39 C +ATOM 6439 C ARG D 93 13.299 -8.341 54.600 1.00 71.74 C +ATOM 6440 O ARG D 93 12.687 -7.276 54.642 1.00 71.06 O +ATOM 6441 CB ARG D 93 13.988 -9.312 56.883 1.00 92.89 C +ATOM 6442 CG ARG D 93 13.496 -10.190 58.051 1.00 96.78 C +ATOM 6443 CD ARG D 93 14.524 -10.406 59.152 1.00100.58 C +ATOM 6444 NE ARG D 93 14.296 -9.564 60.312 1.00 92.16 N +ATOM 6445 CZ ARG D 93 14.905 -8.396 60.530 1.00113.75 C +ATOM 6446 NH1 ARG D 93 15.805 -7.884 59.680 1.00103.38 N +ATOM 6447 NH2 ARG D 93 14.616 -7.743 61.636 1.00147.33 N +ATOM 6448 N LYS D 94 14.164 -8.621 53.632 1.00 84.87 N +ATOM 6449 CA LYS D 94 14.382 -7.677 52.534 1.00 94.35 C +ATOM 6450 C LYS D 94 13.097 -7.570 51.740 1.00 98.09 C +ATOM 6451 O LYS D 94 12.727 -6.464 51.305 1.00108.43 O +ATOM 6452 CB LYS D 94 15.514 -8.146 51.609 1.00 95.08 C +ATOM 6453 CG LYS D 94 16.918 -7.679 51.977 1.00 95.29 C +ATOM 6454 CD LYS D 94 17.944 -8.385 51.109 1.00110.05 C +ATOM 6455 CE LYS D 94 19.281 -7.664 51.063 1.00118.19 C +ATOM 6456 NZ LYS D 94 20.331 -8.565 50.495 1.00128.35 N +ATOM 6457 N ILE D 95 12.437 -8.717 51.526 1.00 72.15 N +ATOM 6458 CA ILE D 95 11.275 -8.735 50.644 1.00 56.63 C +ATOM 6459 C ILE D 95 10.153 -8.007 51.330 1.00 67.66 C +ATOM 6460 O ILE D 95 9.334 -7.328 50.671 1.00 48.21 O +ATOM 6461 CB ILE D 95 10.815 -10.132 50.292 1.00 55.86 C +ATOM 6462 CG1 ILE D 95 11.978 -10.989 49.806 1.00 89.25 C +ATOM 6463 CG2 ILE D 95 9.812 -10.020 49.176 1.00 47.80 C +ATOM 6464 CD1 ILE D 95 11.591 -12.296 49.124 1.00108.87 C +ATOM 6465 N ILE D 96 10.072 -8.215 52.663 1.00 89.45 N +ATOM 6466 CA ILE D 96 9.078 -7.536 53.524 1.00 75.19 C +ATOM 6467 C ILE D 96 9.245 -6.053 53.410 1.00 66.12 C +ATOM 6468 O ILE D 96 8.327 -5.364 52.959 1.00 63.56 O +ATOM 6469 CB ILE D 96 9.198 -7.916 55.011 1.00 55.97 C +ATOM 6470 CG1 ILE D 96 8.767 -9.378 55.216 1.00 77.40 C +ATOM 6471 CG2 ILE D 96 8.276 -7.050 55.824 1.00 50.52 C +ATOM 6472 CD1 ILE D 96 8.791 -9.819 56.660 1.00 80.15 C +ATOM 6473 N ARG D 97 10.437 -5.586 53.747 1.00 62.32 N +ATOM 6474 CA ARG D 97 10.717 -4.159 53.696 1.00 81.71 C +ATOM 6475 C ARG D 97 10.486 -3.546 52.303 1.00101.46 C +ATOM 6476 O ARG D 97 10.086 -2.379 52.177 1.00101.06 O +ATOM 6477 CB ARG D 97 12.148 -3.869 54.138 1.00 94.05 C +ATOM 6478 CG ARG D 97 12.273 -3.357 55.563 1.00102.20 C +ATOM 6479 CD ARG D 97 13.721 -3.031 55.913 1.00 98.45 C +ATOM 6480 NE ARG D 97 14.486 -4.225 56.276 1.00 86.38 N +ATOM 6481 CZ ARG D 97 14.725 -4.615 57.521 1.00 91.21 C +ATOM 6482 NH1 ARG D 97 14.244 -3.923 58.566 1.00 74.09 N +ATOM 6483 NH2 ARG D 97 15.440 -5.718 57.727 1.00109.47 N +ATOM 6484 N ALA D 98 10.722 -4.329 51.255 1.00108.38 N +ATOM 6485 CA ALA D 98 10.488 -3.855 49.900 1.00101.42 C +ATOM 6486 C ALA D 98 8.987 -3.822 49.583 1.00107.16 C +ATOM 6487 O ALA D 98 8.544 -3.008 48.765 1.00100.94 O +ATOM 6488 CB ALA D 98 11.227 -4.744 48.918 1.00114.82 C +ATOM 6489 N ALA D 99 8.223 -4.704 50.241 1.00 96.81 N +ATOM 6490 CA ALA D 99 6.766 -4.800 50.051 1.00 86.64 C +ATOM 6491 C ALA D 99 6.021 -3.619 50.616 1.00 93.41 C +ATOM 6492 O ALA D 99 5.245 -2.946 49.918 1.00158.36 O +ATOM 6493 CB ALA D 99 6.234 -6.037 50.719 1.00 88.60 C +ATOM 6494 N GLN D 100 6.321 -3.297 51.866 1.00 88.92 N +ATOM 6495 CA GLN D 100 5.517 -2.321 52.608 1.00 95.33 C +ATOM 6496 C GLN D 100 6.121 -0.906 52.785 1.00 94.77 C +ATOM 6497 O GLN D 100 5.557 -0.065 53.488 1.00 92.61 O +ATOM 6498 CB GLN D 100 5.157 -2.900 53.970 1.00 86.32 C +ATOM 6499 CG GLN D 100 6.301 -3.571 54.697 1.00 79.39 C +ATOM 6500 CD GLN D 100 5.831 -4.651 55.648 1.00 68.31 C +ATOM 6501 OE1 GLN D 100 5.220 -5.664 55.243 1.00 52.54 O +ATOM 6502 NE2 GLN D 100 6.174 -4.473 56.925 1.00 61.91 N +ATOM 6503 N GLU D 101 7.237 -0.637 52.121 1.00102.15 N +ATOM 6504 CA GLU D 101 7.896 0.658 52.244 1.00116.79 C +ATOM 6505 C GLU D 101 7.066 1.803 51.654 1.00124.34 C +ATOM 6506 O GLU D 101 7.262 2.967 52.023 1.00135.17 O +ATOM 6507 CB GLU D 101 9.296 0.617 51.607 1.00141.47 C +ATOM 6508 CG GLU D 101 9.338 0.095 50.170 1.00148.48 C +ATOM 6509 CD GLU D 101 10.735 0.132 49.572 1.00141.21 C +ATOM 6510 OE1 GLU D 101 11.709 0.278 50.348 1.00134.19 O +ATOM 6511 OE2 GLU D 101 10.858 0.086 48.324 1.00131.82 O +ATOM 6512 N ASN D 102 6.179 1.492 50.711 1.00114.79 N +ATOM 6513 CA ASN D 102 5.413 2.528 50.036 1.00119.74 C +ATOM 6514 C ASN D 102 4.076 2.797 50.701 1.00134.76 C +ATOM 6515 O ASN D 102 3.336 3.686 50.272 1.00174.30 O +ATOM 6516 CB ASN D 102 5.182 2.155 48.581 1.00119.52 C +ATOM 6517 CG ASN D 102 6.436 2.265 47.756 1.00146.33 C +ATOM 6518 OD1 ASN D 102 6.854 3.369 47.363 1.00192.64 O +ATOM 6519 ND2 ASN D 102 7.086 1.129 47.533 1.00166.33 N +ATOM 6520 N GLY D 103 3.759 2.047 51.751 1.00123.61 N +ATOM 6521 CA GLY D 103 2.489 2.237 52.452 1.00118.75 C +ATOM 6522 C GLY D 103 1.270 2.041 51.569 1.00104.79 C +ATOM 6523 O GLY D 103 0.237 2.692 51.747 1.00104.77 O +ATOM 6524 N THR D 104 1.382 1.133 50.610 1.00103.95 N +ATOM 6525 CA THR D 104 0.217 0.674 49.882 1.00108.84 C +ATOM 6526 C THR D 104 -0.259 -0.665 50.458 1.00102.62 C +ATOM 6527 O THR D 104 -1.439 -0.978 50.375 1.00 87.12 O +ATOM 6528 CB THR D 104 0.487 0.553 48.361 1.00111.62 C +ATOM 6529 OG1 THR D 104 1.465 -0.471 48.111 1.00 97.50 O +ATOM 6530 CG2 THR D 104 0.953 1.889 47.794 1.00 91.18 C +ATOM 6531 N VAL D 105 0.640 -1.434 51.070 1.00103.67 N +ATOM 6532 CA VAL D 105 0.307 -2.816 51.456 1.00122.33 C +ATOM 6533 C VAL D 105 -0.841 -2.821 52.453 1.00115.86 C +ATOM 6534 O VAL D 105 -0.916 -1.957 53.333 1.00101.60 O +ATOM 6535 CB VAL D 105 1.535 -3.627 51.987 1.00138.85 C +ATOM 6536 CG1 VAL D 105 1.138 -4.609 53.085 1.00120.42 C +ATOM 6537 CG2 VAL D 105 2.229 -4.384 50.840 1.00140.16 C +ATOM 6538 N ALA D 106 -1.738 -3.790 52.265 1.00127.12 N +ATOM 6539 CA ALA D 106 -2.985 -3.875 52.999 1.00135.26 C +ATOM 6540 C ALA D 106 -2.726 -4.040 54.495 1.00163.32 C +ATOM 6541 O ALA D 106 -1.897 -4.855 54.914 1.00199.80 O +ATOM 6542 CB ALA D 106 -3.816 -5.037 52.475 1.00124.34 C +ATOM 6543 N ILE D 107 -3.452 -3.267 55.299 1.00161.40 N +ATOM 6544 CA ILE D 107 -3.220 -3.202 56.746 1.00155.52 C +ATOM 6545 C ILE D 107 -3.357 -4.578 57.444 1.00149.57 C +ATOM 6546 O ILE D 107 -2.691 -4.853 58.449 1.00112.05 O +ATOM 6547 CB ILE D 107 -4.166 -2.157 57.393 1.00147.11 C +ATOM 6548 CG1 ILE D 107 -3.735 -1.843 58.832 1.00153.99 C +ATOM 6549 CG2 ILE D 107 -5.614 -2.639 57.356 1.00148.82 C +ATOM 6550 CD1 ILE D 107 -2.311 -1.336 58.979 1.00134.93 C +ATOM 6551 N ASN D 108 -4.220 -5.434 56.902 1.00164.88 N +ATOM 6552 CA ASN D 108 -4.383 -6.809 57.393 1.00166.51 C +ATOM 6553 C ASN D 108 -3.160 -7.654 57.064 1.00155.66 C +ATOM 6554 O ASN D 108 -2.774 -8.542 57.822 1.00160.24 O +ATOM 6555 CB ASN D 108 -5.617 -7.470 56.760 1.00166.21 C +ATOM 6556 CG ASN D 108 -6.718 -6.476 56.438 1.00175.74 C +ATOM 6557 OD1 ASN D 108 -7.542 -6.148 57.292 1.00218.28 O +ATOM 6558 ND2 ASN D 108 -6.727 -5.977 55.205 1.00148.67 N +ATOM 6559 N ASN D 109 -2.574 -7.382 55.906 1.00142.54 N +ATOM 6560 CA ASN D 109 -1.470 -8.173 55.381 1.00144.35 C +ATOM 6561 C ASN D 109 -0.103 -7.724 55.910 1.00137.12 C +ATOM 6562 O ASN D 109 0.881 -8.458 55.803 1.00108.00 O +ATOM 6563 CB ASN D 109 -1.486 -8.117 53.849 1.00148.76 C +ATOM 6564 CG ASN D 109 -1.732 -9.472 53.222 1.00158.60 C +ATOM 6565 OD1 ASN D 109 -0.857 -10.024 52.557 1.00168.66 O +ATOM 6566 ND2 ASN D 109 -2.913 -10.036 53.466 1.00163.32 N +ATOM 6567 N ARG D 110 -0.060 -6.513 56.471 1.00132.28 N +ATOM 6568 CA ARG D 110 1.196 -5.842 56.881 1.00 98.27 C +ATOM 6569 C ARG D 110 1.978 -6.683 57.887 1.00 85.12 C +ATOM 6570 O ARG D 110 1.399 -7.235 58.819 1.00105.44 O +ATOM 6571 CB ARG D 110 0.858 -4.488 57.516 1.00 90.83 C +ATOM 6572 CG ARG D 110 1.979 -3.475 57.490 1.00104.54 C +ATOM 6573 CD ARG D 110 1.458 -2.054 57.325 1.00116.47 C +ATOM 6574 NE ARG D 110 1.160 -1.416 58.609 1.00140.48 N +ATOM 6575 CZ ARG D 110 1.739 -0.299 59.064 1.00156.67 C +ATOM 6576 NH1 ARG D 110 2.681 0.338 58.360 1.00134.33 N +ATOM 6577 NH2 ARG D 110 1.365 0.194 60.243 1.00165.04 N +ATOM 6578 N ILE D 111 3.282 -6.815 57.684 1.00 76.16 N +ATOM 6579 CA ILE D 111 4.127 -7.515 58.653 1.00 75.42 C +ATOM 6580 C ILE D 111 5.029 -6.530 59.381 1.00 82.48 C +ATOM 6581 O ILE D 111 5.862 -5.909 58.743 1.00 75.03 O +ATOM 6582 CB ILE D 111 5.016 -8.568 57.986 1.00 69.71 C +ATOM 6583 CG1 ILE D 111 4.141 -9.661 57.369 1.00 85.26 C +ATOM 6584 CG2 ILE D 111 5.975 -9.177 59.009 1.00 58.69 C +ATOM 6585 CD1 ILE D 111 4.881 -10.606 56.431 1.00107.64 C +ATOM 6586 N PRO D 112 4.880 -6.407 60.715 1.00102.69 N +ATOM 6587 CA PRO D 112 5.662 -5.446 61.474 1.00 93.32 C +ATOM 6588 C PRO D 112 7.037 -6.017 61.761 1.00114.15 C +ATOM 6589 O PRO D 112 7.164 -7.165 62.228 1.00 75.59 O +ATOM 6590 CB PRO D 112 4.864 -5.278 62.759 1.00 85.53 C +ATOM 6591 CG PRO D 112 4.212 -6.608 62.958 1.00105.40 C +ATOM 6592 CD PRO D 112 4.019 -7.225 61.592 1.00122.18 C +ATOM 6593 N LEU D 113 8.062 -5.233 61.431 1.00133.28 N +ATOM 6594 CA LEU D 113 9.439 -5.698 61.511 1.00117.78 C +ATOM 6595 C LEU D 113 10.175 -5.090 62.679 1.00104.22 C +ATOM 6596 O LEU D 113 10.057 -3.895 62.988 1.00 99.05 O +ATOM 6597 CB LEU D 113 10.199 -5.413 60.224 1.00114.90 C +ATOM 6598 CG LEU D 113 10.068 -6.487 59.150 1.00116.77 C +ATOM 6599 CD1 LEU D 113 10.954 -6.078 57.993 1.00139.42 C +ATOM 6600 CD2 LEU D 113 10.451 -7.876 59.648 1.00101.54 C +ATOM 6601 N GLN D 114 10.980 -5.936 63.298 1.00 88.06 N +ATOM 6602 CA GLN D 114 11.592 -5.628 64.556 1.00 95.97 C +ATOM 6603 C GLN D 114 12.989 -6.143 64.410 1.00 99.63 C +ATOM 6604 O GLN D 114 13.205 -7.148 63.715 1.00149.07 O +ATOM 6605 CB GLN D 114 10.845 -6.356 65.672 1.00 89.83 C +ATOM 6606 CG GLN D 114 10.901 -5.661 67.009 1.00 89.96 C +ATOM 6607 CD GLN D 114 10.789 -6.667 68.119 1.00105.06 C +ATOM 6608 OE1 GLN D 114 10.155 -7.716 67.952 1.00118.11 O +ATOM 6609 NE2 GLN D 114 11.409 -6.369 69.264 1.00124.92 N +ATOM 6610 N SER D 115 13.937 -5.460 65.037 1.00 81.83 N +ATOM 6611 CA SER D 115 15.319 -5.875 64.965 1.00 87.97 C +ATOM 6612 C SER D 115 15.489 -7.352 65.382 1.00 81.81 C +ATOM 6613 O SER D 115 14.681 -7.901 66.137 1.00 51.92 O +ATOM 6614 CB SER D 115 16.195 -4.978 65.845 1.00 90.10 C +ATOM 6615 OG SER D 115 15.725 -4.949 67.182 1.00 88.46 O +ATOM 6616 N LEU D 116 16.520 -8.010 64.854 1.00 84.67 N +ATOM 6617 CA LEU D 116 16.583 -9.434 65.038 1.00 88.46 C +ATOM 6618 C LEU D 116 16.914 -9.641 66.497 1.00 99.98 C +ATOM 6619 O LEU D 116 17.913 -9.093 66.977 1.00144.26 O +ATOM 6620 CB LEU D 116 17.639 -10.080 64.140 1.00 93.75 C +ATOM 6621 CG LEU D 116 17.369 -10.033 62.648 1.00 88.68 C +ATOM 6622 CD1 LEU D 116 18.054 -8.830 61.986 1.00108.35 C +ATOM 6623 CD2 LEU D 116 17.862 -11.339 62.033 1.00 98.11 C +ATOM 6624 N THR D 117 16.106 -10.442 67.184 1.00 98.56 N +ATOM 6625 CA THR D 117 16.376 -10.791 68.571 1.00109.65 C +ATOM 6626 C THR D 117 17.783 -11.365 68.674 1.00 98.12 C +ATOM 6627 O THR D 117 18.146 -12.244 67.901 1.00116.26 O +ATOM 6628 CB THR D 117 15.375 -11.831 69.117 1.00 96.55 C +ATOM 6629 OG1 THR D 117 14.041 -11.363 68.893 1.00138.92 O +ATOM 6630 CG2 THR D 117 15.570 -12.030 70.605 1.00 95.43 C +ATOM 6631 N ALA D 118 18.550 -10.873 69.641 1.00 77.45 N +ATOM 6632 CA ALA D 118 19.952 -11.187 69.719 1.00 75.16 C +ATOM 6633 C ALA D 118 20.242 -12.012 70.950 1.00 96.91 C +ATOM 6634 O ALA D 118 19.795 -11.680 72.064 1.00123.09 O +ATOM 6635 CB ALA D 118 20.776 -9.915 69.723 1.00 63.73 C +ATOM 6636 N ALA D 119 21.151 -12.961 70.770 1.00 94.62 N +ATOM 6637 CA ALA D 119 21.550 -13.871 71.821 1.00105.71 C +ATOM 6638 C ALA D 119 22.656 -13.332 72.739 1.00 97.58 C +ATOM 6639 O ALA D 119 23.456 -12.483 72.325 1.00 54.34 O +ATOM 6640 CB ALA D 119 22.021 -15.159 71.197 1.00147.46 C +ATOM 6641 N ASN D 120 22.708 -13.847 73.980 1.00 97.76 N +ATOM 6642 CA ASN D 120 23.787 -13.483 74.894 1.00 93.12 C +ATOM 6643 C ASN D 120 24.869 -14.516 74.962 1.00 70.02 C +ATOM 6644 O ASN D 120 26.074 -14.198 74.916 1.00 80.49 O +ATOM 6645 CB ASN D 120 23.301 -13.223 76.310 1.00101.93 C +ATOM 6646 CG ASN D 120 24.435 -12.735 77.220 1.00123.58 C +ATOM 6647 OD1 ASN D 120 24.525 -13.168 78.363 1.00190.22 O +ATOM 6648 ND2 ASN D 120 25.354 -11.890 76.691 1.00102.07 N +ATOM 6649 N ILE D 121 24.464 -15.755 75.104 1.00 63.61 N +ATOM 6650 CA ILE D 121 25.430 -16.813 75.000 1.00115.99 C +ATOM 6651 C ILE D 121 25.167 -17.530 73.681 1.00120.32 C +ATOM 6652 O ILE D 121 24.039 -17.737 73.299 1.00 89.32 O +ATOM 6653 CB ILE D 121 25.389 -17.780 76.224 1.00157.14 C +ATOM 6654 CG1 ILE D 121 24.145 -18.684 76.200 1.00168.81 C +ATOM 6655 CG2 ILE D 121 25.479 -16.999 77.528 1.00140.40 C +ATOM 6656 CD1 ILE D 121 24.457 -20.145 75.928 1.00190.51 C +ATOM 6657 N MET D 122 26.228 -17.968 73.018 1.00145.32 N +ATOM 6658 CA MET D 122 26.058 -18.923 71.955 1.00126.02 C +ATOM 6659 C MET D 122 26.851 -20.196 72.249 1.00108.38 C +ATOM 6660 O MET D 122 27.903 -20.159 72.888 1.00 71.77 O +ATOM 6661 CB MET D 122 26.453 -18.282 70.634 1.00149.56 C +ATOM 6662 CG MET D 122 27.880 -17.754 70.551 1.00133.44 C +ATOM 6663 SD MET D 122 28.439 -17.798 68.840 1.00106.31 S +ATOM 6664 CE MET D 122 30.103 -18.386 69.033 1.00107.36 C +ATOM 6665 N VAL D 123 26.263 -21.331 71.898 1.00 89.24 N +ATOM 6666 CA VAL D 123 26.900 -22.608 72.171 1.00 99.08 C +ATOM 6667 C VAL D 123 27.233 -23.320 70.887 1.00 87.90 C +ATOM 6668 O VAL D 123 26.376 -23.494 70.014 1.00 69.75 O +ATOM 6669 CB VAL D 123 26.014 -23.538 73.010 1.00120.61 C +ATOM 6670 CG1 VAL D 123 24.564 -23.450 72.574 1.00125.38 C +ATOM 6671 CG2 VAL D 123 26.519 -24.986 72.945 1.00150.49 C +ATOM 6672 N GLU D 124 28.493 -23.731 70.758 1.00 85.50 N +ATOM 6673 CA GLU D 124 28.913 -24.527 69.600 1.00 97.34 C +ATOM 6674 C GLU D 124 29.671 -25.740 70.056 1.00 72.54 C +ATOM 6675 O GLU D 124 30.006 -25.855 71.196 1.00 50.29 O +ATOM 6676 CB GLU D 124 29.777 -23.718 68.609 1.00121.45 C +ATOM 6677 CG GLU D 124 30.614 -22.612 69.214 1.00121.52 C +ATOM 6678 CD GLU D 124 31.100 -21.639 68.161 1.00133.18 C +ATOM 6679 OE1 GLU D 124 30.344 -21.330 67.218 1.00162.25 O +ATOM 6680 OE2 GLU D 124 32.217 -21.137 68.296 1.00149.77 O +ATOM 6681 N GLY D 125 29.923 -26.643 69.121 1.00 87.33 N +ATOM 6682 CA GLY D 125 30.538 -27.906 69.432 1.00 88.06 C +ATOM 6683 C GLY D 125 30.875 -28.693 68.185 1.00 89.67 C +ATOM 6684 O GLY D 125 30.917 -28.158 67.076 1.00 88.86 O +ATOM 6685 N SER D 126 31.071 -29.985 68.360 1.00 87.62 N +ATOM 6686 CA SER D 126 31.540 -30.808 67.266 1.00 83.48 C +ATOM 6687 C SER D 126 31.269 -32.254 67.596 1.00 88.51 C +ATOM 6688 O SER D 126 31.310 -32.646 68.754 1.00 93.76 O +ATOM 6689 CB SER D 126 33.047 -30.631 67.039 1.00 66.54 C +ATOM 6690 OG SER D 126 33.478 -29.314 67.347 1.00 59.28 O +ATOM 6691 N ILE D 127 31.028 -33.059 66.570 1.00 88.87 N +ATOM 6692 CA ILE D 127 31.057 -34.495 66.752 1.00 81.52 C +ATOM 6693 C ILE D 127 32.505 -34.901 66.733 1.00102.84 C +ATOM 6694 O ILE D 127 33.140 -34.963 65.681 1.00156.59 O +ATOM 6695 CB ILE D 127 30.268 -35.252 65.674 1.00 90.17 C +ATOM 6696 CG1 ILE D 127 28.749 -34.961 65.796 1.00 94.56 C +ATOM 6697 CG2 ILE D 127 30.516 -36.748 65.800 1.00 92.42 C +ATOM 6698 CD1 ILE D 127 27.981 -35.022 64.480 1.00 64.73 C +ATOM 6699 N ILE D 128 33.051 -35.153 67.917 1.00108.49 N +ATOM 6700 CA ILE D 128 34.462 -35.492 68.049 1.00 99.04 C +ATOM 6701 C ILE D 128 34.669 -36.999 68.117 1.00 96.32 C +ATOM 6702 O ILE D 128 34.660 -37.588 69.198 1.00128.07 O +ATOM 6703 CB ILE D 128 35.083 -34.843 69.300 1.00 93.49 C +ATOM 6704 CG1 ILE D 128 35.104 -33.320 69.157 1.00 86.75 C +ATOM 6705 CG2 ILE D 128 36.487 -35.380 69.537 1.00107.08 C +ATOM 6706 CD1 ILE D 128 35.451 -32.591 70.436 1.00 96.15 C +ATOM 6707 N GLY D 129 34.856 -37.620 66.957 1.00 85.41 N +ATOM 6708 CA GLY D 129 35.081 -39.054 66.902 1.00118.48 C +ATOM 6709 C GLY D 129 33.902 -40.034 66.754 1.00132.50 C +ATOM 6710 O GLY D 129 32.829 -39.906 67.369 1.00139.42 O +ATOM 6711 N TYR D 130 34.119 -41.004 65.876 1.00114.86 N +ATOM 6712 CA TYR D 130 33.291 -42.201 65.796 1.00 91.21 C +ATOM 6713 C TYR D 130 34.234 -43.335 65.500 1.00 85.06 C +ATOM 6714 O TYR D 130 34.867 -43.374 64.440 1.00 76.42 O +ATOM 6715 CB TYR D 130 32.263 -42.086 64.676 1.00 98.34 C +ATOM 6716 CG TYR D 130 31.473 -43.333 64.414 1.00100.28 C +ATOM 6717 CD1 TYR D 130 32.074 -44.475 63.850 1.00 94.77 C +ATOM 6718 CD2 TYR D 130 30.104 -43.348 64.633 1.00118.95 C +ATOM 6719 CE1 TYR D 130 31.330 -45.606 63.556 1.00105.02 C +ATOM 6720 CE2 TYR D 130 29.349 -44.476 64.352 1.00138.80 C +ATOM 6721 CZ TYR D 130 29.966 -45.604 63.827 1.00120.83 C +ATOM 6722 OH TYR D 130 29.186 -46.715 63.605 1.00122.58 O +ATOM 6723 N GLU D 131 34.514 -44.133 66.509 1.00111.42 N +ATOM 6724 CA GLU D 131 35.354 -45.309 66.305 1.00138.60 C +ATOM 6725 C GLU D 131 34.408 -46.483 66.114 1.00142.48 C +ATOM 6726 O GLU D 131 33.323 -46.492 66.685 1.00106.75 O +ATOM 6727 CB GLU D 131 36.297 -45.507 67.496 1.00133.58 C +ATOM 6728 CG GLU D 131 37.340 -46.595 67.323 1.00130.15 C +ATOM 6729 CD GLU D 131 38.611 -46.123 66.626 1.00162.38 C +ATOM 6730 OE1 GLU D 131 38.967 -44.923 66.751 1.00226.93 O +ATOM 6731 OE2 GLU D 131 39.301 -46.969 66.007 1.00165.04 O +ATOM 6732 N SER D 132 34.812 -47.450 65.292 1.00150.87 N +ATOM 6733 CA SER D 132 33.916 -48.526 64.897 1.00135.68 C +ATOM 6734 C SER D 132 34.427 -49.907 65.344 1.00162.68 C +ATOM 6735 O SER D 132 35.632 -50.190 65.256 1.00156.40 O +ATOM 6736 CB SER D 132 33.704 -48.485 63.385 1.00113.41 C +ATOM 6737 OG SER D 132 34.285 -49.616 62.762 1.00 96.68 O +ATOM 6738 N ASN D 133 33.500 -50.761 65.791 1.00151.19 N +ATOM 6739 CA ASN D 133 33.844 -52.045 66.420 1.00149.46 C +ATOM 6740 C ASN D 133 34.902 -51.874 67.497 1.00156.18 C +ATOM 6741 O ASN D 133 35.980 -52.473 67.445 1.00105.03 O +ATOM 6742 CB ASN D 133 34.321 -53.070 65.390 1.00148.71 C +ATOM 6743 CG ASN D 133 33.259 -53.386 64.352 1.00137.94 C +ATOM 6744 OD1 ASN D 133 32.055 -53.307 64.612 1.00 73.53 O +ATOM 6745 ND2 ASN D 133 33.709 -53.742 63.158 1.00140.73 N +ATOM 6746 N VAL D 134 34.590 -50.997 68.443 1.00180.79 N +ATOM 6747 CA VAL D 134 35.487 -50.691 69.549 1.00163.69 C +ATOM 6748 C VAL D 134 35.568 -51.950 70.391 1.00157.87 C +ATOM 6749 O VAL D 134 36.611 -52.275 70.953 1.00126.31 O +ATOM 6750 CB VAL D 134 34.963 -49.485 70.371 1.00163.51 C +ATOM 6751 CG1 VAL D 134 35.921 -49.121 71.488 1.00142.04 C +ATOM 6752 CG2 VAL D 134 34.756 -48.274 69.460 1.00223.27 C +ATOM 6753 N LYS D 135 34.448 -52.663 70.467 1.00191.49 N +ATOM 6754 CA LYS D 135 34.457 -54.035 70.973 1.00180.03 C +ATOM 6755 C LYS D 135 33.601 -54.937 70.102 1.00177.05 C +ATOM 6756 O LYS D 135 32.689 -54.476 69.386 1.00238.36 O +ATOM 6757 CB LYS D 135 33.938 -54.092 72.413 1.00191.55 C +ATOM 6758 CG LYS D 135 34.799 -53.330 73.404 1.00197.67 C +ATOM 6759 CD LYS D 135 34.163 -53.341 74.782 1.00197.15 C +ATOM 6760 CE LYS D 135 34.991 -52.572 75.787 1.00183.21 C +ATOM 6761 NZ LYS D 135 34.654 -52.997 77.168 1.00171.78 N +ATOM 6762 N SER D 136 33.868 -56.232 70.205 1.00130.99 N +ATOM 6763 CA SER D 136 33.112 -57.218 69.462 1.00119.86 C +ATOM 6764 C SER D 136 33.319 -58.596 70.036 1.00109.62 C +ATOM 6765 O SER D 136 34.333 -58.874 70.674 1.00116.44 O +ATOM 6766 CB SER D 136 33.496 -57.186 67.975 1.00141.46 C +ATOM 6767 OG SER D 136 33.926 -58.461 67.513 1.00138.70 O +ATOM 6768 N GLY D 137 32.375 -59.483 69.763 1.00127.78 N +ATOM 6769 CA GLY D 137 32.490 -60.878 70.204 1.00168.54 C +ATOM 6770 C GLY D 137 31.489 -61.812 69.549 1.00181.70 C +ATOM 6771 O GLY D 137 30.604 -61.364 68.815 1.00265.37 O +ATOM 6772 N GLY D 138 31.601 -63.104 69.842 1.00135.40 N +ATOM 6773 CA GLY D 138 30.671 -64.084 69.304 1.00128.35 C +ATOM 6774 C GLY D 138 30.732 -65.410 70.019 1.00147.84 C +ATOM 6775 O GLY D 138 31.788 -65.820 70.498 1.00157.51 O +ATOM 6776 N VAL D 139 29.578 -66.065 70.132 1.00180.58 N +ATOM 6777 CA VAL D 139 29.489 -67.388 70.755 1.00182.33 C +ATOM 6778 C VAL D 139 28.544 -68.280 69.963 1.00181.95 C +ATOM 6779 O VAL D 139 27.395 -67.909 69.706 1.00191.23 O +ATOM 6780 CB VAL D 139 28.973 -67.316 72.206 1.00165.11 C +ATOM 6781 CG1 VAL D 139 28.773 -68.716 72.755 1.00159.15 C +ATOM 6782 CG2 VAL D 139 29.936 -66.529 73.082 1.00173.92 C +ATOM 6783 N GLY D 140 29.034 -69.455 69.576 1.00178.62 N +ATOM 6784 CA GLY D 140 28.250 -70.385 68.771 1.00192.76 C +ATOM 6785 C GLY D 140 28.566 -71.846 69.040 1.00187.89 C +ATOM 6786 O GLY D 140 29.707 -72.207 69.311 1.00190.98 O +ATOM 6787 N ALA D 141 27.543 -72.690 68.956 1.00178.99 N +ATOM 6788 CA ALA D 141 27.696 -74.115 69.230 1.00170.87 C +ATOM 6789 C ALA D 141 26.799 -74.974 68.335 1.00175.86 C +ATOM 6790 O ALA D 141 25.660 -74.601 68.020 1.00161.54 O +ATOM 6791 CB ALA D 141 27.414 -74.387 70.695 1.00156.92 C +ATOM 6792 N ARG D 142 27.351 -76.086 67.871 1.00179.19 N +ATOM 6793 CA ARG D 142 26.599 -77.013 67.055 1.00171.21 C +ATOM 6794 C ARG D 142 26.775 -78.418 67.613 1.00200.63 C +ATOM 6795 O ARG D 142 27.828 -78.757 68.146 1.00206.45 O +ATOM 6796 CB ARG D 142 27.046 -76.948 65.592 1.00150.37 C +ATOM 6797 CG ARG D 142 26.218 -77.838 64.672 1.00153.67 C +ATOM 6798 CD ARG D 142 25.886 -77.164 63.350 1.00165.29 C +ATOM 6799 NE ARG D 142 26.987 -77.291 62.405 1.00171.14 N +ATOM 6800 CZ ARG D 142 27.228 -76.455 61.402 1.00210.79 C +ATOM 6801 NH1 ARG D 142 26.466 -75.386 61.219 1.00234.02 N +ATOM 6802 NH2 ARG D 142 28.269 -76.662 60.603 1.00236.82 N +ATOM 6803 N TYR D 143 25.718 -79.219 67.519 1.00207.64 N +ATOM 6804 CA TYR D 143 25.671 -80.541 68.139 1.00202.63 C +ATOM 6805 C TYR D 143 25.185 -81.604 67.151 1.00176.84 C +ATOM 6806 O TYR D 143 23.996 -81.940 67.096 1.00185.24 O +ATOM 6807 CB TYR D 143 24.764 -80.503 69.370 1.00222.43 C +ATOM 6808 CG TYR D 143 24.748 -81.778 70.147 1.00232.85 C +ATOM 6809 CD1 TYR D 143 25.846 -82.159 70.900 1.00227.08 C +ATOM 6810 CD2 TYR D 143 23.628 -82.601 70.144 1.00218.03 C +ATOM 6811 CE1 TYR D 143 25.826 -83.330 71.638 1.00208.18 C +ATOM 6812 CE2 TYR D 143 23.591 -83.770 70.889 1.00184.58 C +ATOM 6813 CZ TYR D 143 24.697 -84.134 71.626 1.00180.80 C +ATOM 6814 OH TYR D 143 24.682 -85.299 72.351 1.00167.89 O +ATOM 6815 N GLY D 145 23.899 -81.980 64.798 1.00142.86 N +ATOM 6816 CA GLY D 145 23.076 -81.576 63.663 1.00128.88 C +ATOM 6817 C GLY D 145 22.492 -80.193 63.816 1.00131.82 C +ATOM 6818 O GLY D 145 22.170 -79.546 62.818 1.00129.96 O +ATOM 6819 N ILE D 146 22.399 -79.713 65.054 1.00155.16 N +ATOM 6820 CA ILE D 146 21.697 -78.493 65.360 1.00169.33 C +ATOM 6821 C ILE D 146 22.607 -77.453 65.969 1.00181.89 C +ATOM 6822 O ILE D 146 23.433 -77.784 66.796 1.00178.31 O +ATOM 6823 CB ILE D 146 20.622 -78.847 66.379 1.00147.87 C +ATOM 6824 CG1 ILE D 146 19.952 -77.641 67.006 1.00134.85 C +ATOM 6825 CG2 ILE D 146 21.117 -79.850 67.426 1.00140.01 C +ATOM 6826 CD1 ILE D 146 18.468 -77.790 67.273 1.00129.41 C +ATOM 6827 N GLY D 147 22.430 -76.193 65.584 1.00173.44 N +ATOM 6828 CA GLY D 147 23.371 -75.166 65.988 1.00157.41 C +ATOM 6829 C GLY D 147 22.799 -73.767 66.102 1.00172.71 C +ATOM 6830 O GLY D 147 21.793 -73.418 65.485 1.00207.95 O +ATOM 6831 N ALA D 148 23.455 -72.957 66.915 1.00190.07 N +ATOM 6832 CA ALA D 148 23.094 -71.558 67.049 1.00184.28 C +ATOM 6833 C ALA D 148 24.341 -70.724 67.317 1.00177.70 C +ATOM 6834 O ALA D 148 25.414 -71.265 67.629 1.00229.01 O +ATOM 6835 CB ALA D 148 22.062 -71.383 68.156 1.00156.85 C +ATOM 6836 N ASP D 149 24.201 -69.412 67.166 1.00140.64 N +ATOM 6837 CA ASP D 149 25.303 -68.503 67.453 1.00139.74 C +ATOM 6838 C ASP D 149 24.808 -67.067 67.572 1.00147.89 C +ATOM 6839 O ASP D 149 23.816 -66.688 66.943 1.00171.46 O +ATOM 6840 CB ASP D 149 26.380 -68.616 66.372 1.00135.18 C +ATOM 6841 CG ASP D 149 26.028 -67.865 65.136 1.00140.61 C +ATOM 6842 OD1 ASP D 149 25.157 -68.346 64.386 1.00152.13 O +ATOM 6843 OD2 ASP D 149 26.608 -66.784 64.917 1.00149.25 O +ATOM 6844 N THR D 150 25.462 -66.285 68.423 1.00163.47 N +ATOM 6845 CA THR D 150 25.274 -64.843 68.394 1.00172.14 C +ATOM 6846 C THR D 150 26.610 -64.158 68.150 1.00186.37 C +ATOM 6847 O THR D 150 27.675 -64.714 68.439 1.00225.21 O +ATOM 6848 CB THR D 150 24.647 -64.295 69.695 1.00145.57 C +ATOM 6849 OG1 THR D 150 25.487 -64.615 70.805 1.00141.60 O +ATOM 6850 CG2 THR D 150 23.261 -64.863 69.911 1.00124.66 C +ATOM 6851 N GLN D 151 26.539 -62.959 67.592 1.00148.61 N +ATOM 6852 CA GLN D 151 27.693 -62.115 67.418 1.00114.67 C +ATOM 6853 C GLN D 151 27.300 -60.708 67.792 1.00111.78 C +ATOM 6854 O GLN D 151 26.191 -60.291 67.539 1.00106.18 O +ATOM 6855 CB GLN D 151 28.144 -62.186 65.971 1.00116.97 C +ATOM 6856 CG GLN D 151 28.793 -63.509 65.629 1.00141.18 C +ATOM 6857 CD GLN D 151 28.758 -63.792 64.147 1.00165.07 C +ATOM 6858 OE1 GLN D 151 28.985 -62.893 63.342 1.00186.26 O +ATOM 6859 NE2 GLN D 151 28.489 -65.044 63.776 1.00168.45 N +ATOM 6860 N TYR D 152 28.202 -59.973 68.419 1.00134.00 N +ATOM 6861 CA TYR D 152 27.910 -58.582 68.740 1.00137.46 C +ATOM 6862 C TYR D 152 29.084 -57.657 68.429 1.00153.89 C +ATOM 6863 O TYR D 152 30.246 -58.069 68.511 1.00176.72 O +ATOM 6864 CB TYR D 152 27.490 -58.452 70.192 1.00105.36 C +ATOM 6865 CG TYR D 152 28.534 -57.860 71.133 1.00114.55 C +ATOM 6866 CD1 TYR D 152 29.764 -58.509 71.388 1.00 89.22 C +ATOM 6867 CD2 TYR D 152 28.268 -56.685 71.817 1.00108.64 C +ATOM 6868 CE1 TYR D 152 30.717 -57.966 72.244 1.00 68.12 C +ATOM 6869 CE2 TYR D 152 29.174 -56.178 72.741 1.00103.65 C +ATOM 6870 CZ TYR D 152 30.392 -56.823 72.954 1.00 86.26 C +ATOM 6871 OH TYR D 152 31.240 -56.341 73.909 1.00 80.43 O +ATOM 6872 N GLN D 153 28.772 -56.436 67.995 1.00121.25 N +ATOM 6873 CA GLN D 153 29.783 -55.413 67.843 1.00 95.95 C +ATOM 6874 C GLN D 153 29.279 -54.120 68.457 1.00106.75 C +ATOM 6875 O GLN D 153 28.065 -53.882 68.549 1.00125.35 O +ATOM 6876 CB GLN D 153 30.115 -55.215 66.360 1.00102.05 C +ATOM 6877 CG GLN D 153 30.782 -56.423 65.713 1.00114.30 C +ATOM 6878 CD GLN D 153 29.818 -57.554 65.278 1.00110.22 C +ATOM 6879 OE1 GLN D 153 28.596 -57.415 65.351 1.00 85.59 O +ATOM 6880 NE2 GLN D 153 30.379 -58.634 64.737 1.00111.17 N +ATOM 6881 N LEU D 154 30.205 -53.267 68.881 1.00125.89 N +ATOM 6882 CA LEU D 154 29.816 -51.930 69.340 1.00141.32 C +ATOM 6883 C LEU D 154 30.832 -50.842 68.973 1.00134.86 C +ATOM 6884 O LEU D 154 32.049 -51.068 69.026 1.00118.51 O +ATOM 6885 CB LEU D 154 29.540 -51.931 70.851 1.00135.22 C +ATOM 6886 CG LEU D 154 30.770 -52.069 71.760 1.00173.02 C +ATOM 6887 CD1 LEU D 154 31.282 -50.711 72.213 1.00161.90 C +ATOM 6888 CD2 LEU D 154 30.433 -52.954 72.950 1.00208.14 C +ATOM 6889 N ASP D 155 30.286 -49.645 68.738 1.00123.15 N +ATOM 6890 CA ASP D 155 30.995 -48.496 68.189 1.00 93.44 C +ATOM 6891 C ASP D 155 30.837 -47.313 69.133 1.00 99.23 C +ATOM 6892 O ASP D 155 30.000 -47.339 70.049 1.00 87.56 O +ATOM 6893 CB ASP D 155 30.384 -48.100 66.861 1.00101.04 C +ATOM 6894 CG ASP D 155 30.158 -49.292 65.955 1.00143.31 C +ATOM 6895 OD1 ASP D 155 29.136 -50.007 66.137 1.00212.05 O +ATOM 6896 OD2 ASP D 155 30.972 -49.503 65.035 1.00129.58 O +ATOM 6897 N GLN D 156 31.724 -46.327 69.006 1.00130.20 N +ATOM 6898 CA GLN D 156 31.727 -45.179 69.941 1.00142.54 C +ATOM 6899 C GLN D 156 31.446 -43.890 69.206 1.00129.12 C +ATOM 6900 O GLN D 156 31.654 -43.805 68.004 1.00116.24 O +ATOM 6901 CB GLN D 156 33.066 -45.059 70.689 1.00142.26 C +ATOM 6902 CG GLN D 156 33.050 -44.071 71.843 1.00130.29 C +ATOM 6903 CD GLN D 156 34.164 -44.326 72.848 1.00147.99 C +ATOM 6904 OE1 GLN D 156 35.074 -45.135 72.615 1.00133.46 O +ATOM 6905 NE2 GLN D 156 34.098 -43.632 73.981 1.00168.27 N +ATOM 6906 N ILE D 157 30.904 -42.917 69.921 1.00115.68 N +ATOM 6907 CA ILE D 157 30.643 -41.615 69.346 1.00124.74 C +ATOM 6908 C ILE D 157 30.781 -40.591 70.474 1.00142.22 C +ATOM 6909 O ILE D 157 30.326 -40.824 71.603 1.00176.02 O +ATOM 6910 CB ILE D 157 29.246 -41.571 68.681 1.00134.75 C +ATOM 6911 CG1 ILE D 157 29.178 -40.486 67.609 1.00118.55 C +ATOM 6912 CG2 ILE D 157 28.149 -41.347 69.723 1.00165.67 C +ATOM 6913 CD1 ILE D 157 27.899 -40.500 66.782 1.00100.17 C +ATOM 6914 N ALA D 158 31.420 -39.464 70.192 1.00123.03 N +ATOM 6915 CA ALA D 158 31.588 -38.453 71.226 1.00100.58 C +ATOM 6916 C ALA D 158 31.196 -37.083 70.705 1.00 84.17 C +ATOM 6917 O ALA D 158 31.302 -36.819 69.504 1.00 90.11 O +ATOM 6918 CB ALA D 158 33.014 -38.473 71.751 1.00 77.49 C +ATOM 6919 N VAL D 159 30.736 -36.232 71.614 1.00 60.66 N +ATOM 6920 CA VAL D 159 30.268 -34.924 71.241 1.00 75.43 C +ATOM 6921 C VAL D 159 30.715 -33.832 72.200 1.00 85.00 C +ATOM 6922 O VAL D 159 30.712 -34.002 73.425 1.00134.98 O +ATOM 6923 CB VAL D 159 28.751 -34.903 71.198 1.00108.17 C +ATOM 6924 CG1 VAL D 159 28.225 -33.478 71.302 1.00132.35 C +ATOM 6925 CG2 VAL D 159 28.255 -35.548 69.923 1.00135.86 C +ATOM 6926 N ASN D 160 31.256 -32.752 71.628 1.00101.09 N +ATOM 6927 CA ASN D 160 31.703 -31.571 72.406 1.00100.06 C +ATOM 6928 C ASN D 160 30.653 -30.524 72.242 1.00102.60 C +ATOM 6929 O ASN D 160 30.170 -30.319 71.122 1.00128.65 O +ATOM 6930 CB ASN D 160 33.050 -31.027 71.864 1.00105.03 C +ATOM 6931 CG ASN D 160 33.482 -29.702 72.495 1.00101.96 C +ATOM 6932 OD1 ASN D 160 32.697 -28.787 72.695 1.00 85.75 O +ATOM 6933 ND2 ASN D 160 34.761 -29.620 72.835 1.00111.23 N +ATOM 6934 N LEU D 161 30.148 -30.037 73.364 1.00 86.96 N +ATOM 6935 CA LEU D 161 29.382 -28.814 73.346 1.00 78.84 C +ATOM 6936 C LEU D 161 30.067 -27.801 74.229 1.00 78.79 C +ATOM 6937 O LEU D 161 30.636 -28.125 75.257 1.00 74.39 O +ATOM 6938 CB LEU D 161 27.962 -29.063 73.824 1.00 75.15 C +ATOM 6939 CG LEU D 161 27.131 -29.983 72.948 1.00 87.67 C +ATOM 6940 CD1 LEU D 161 25.817 -30.304 73.634 1.00103.16 C +ATOM 6941 CD2 LEU D 161 26.893 -29.320 71.594 1.00104.84 C +ATOM 6942 N ARG D 162 29.958 -26.535 73.878 1.00102.95 N +ATOM 6943 CA ARG D 162 30.579 -25.494 74.702 1.00111.41 C +ATOM 6944 C ARG D 162 29.904 -24.106 74.607 1.00102.39 C +ATOM 6945 O ARG D 162 29.587 -23.624 73.524 1.00 84.22 O +ATOM 6946 CB ARG D 162 32.079 -25.408 74.412 1.00 98.17 C +ATOM 6947 CG ARG D 162 32.459 -24.993 73.007 1.00116.80 C +ATOM 6948 CD ARG D 162 33.910 -24.553 72.976 1.00107.75 C +ATOM 6949 NE ARG D 162 34.285 -23.949 71.682 1.00112.20 N +ATOM 6950 CZ ARG D 162 34.598 -24.612 70.570 1.00 85.16 C +ATOM 6951 NH1 ARG D 162 34.588 -25.939 70.582 1.00100.47 N +ATOM 6952 NH2 ARG D 162 34.894 -23.939 69.448 1.00 61.27 N +ATOM 6953 N VAL D 163 29.660 -23.515 75.776 1.00 98.51 N +ATOM 6954 CA VAL D 163 29.013 -22.206 75.895 1.00 90.51 C +ATOM 6955 C VAL D 163 30.050 -21.141 75.812 1.00 92.08 C +ATOM 6956 O VAL D 163 30.991 -21.107 76.624 1.00159.70 O +ATOM 6957 CB VAL D 163 28.344 -22.012 77.267 1.00102.49 C +ATOM 6958 CG1 VAL D 163 27.751 -20.608 77.363 1.00 73.30 C +ATOM 6959 CG2 VAL D 163 27.305 -23.111 77.511 1.00125.24 C +ATOM 6960 N VAL D 164 29.860 -20.251 74.862 1.00 87.91 N +ATOM 6961 CA VAL D 164 30.772 -19.139 74.638 1.00115.69 C +ATOM 6962 C VAL D 164 30.051 -17.846 74.955 1.00100.34 C +ATOM 6963 O VAL D 164 28.896 -17.669 74.557 1.00 94.97 O +ATOM 6964 CB VAL D 164 31.229 -19.060 73.178 1.00138.68 C +ATOM 6965 CG1 VAL D 164 32.127 -17.857 72.969 1.00144.11 C +ATOM 6966 CG2 VAL D 164 31.963 -20.321 72.803 1.00148.00 C +ATOM 6967 N ASN D 165 30.743 -16.955 75.664 1.00 71.75 N +ATOM 6968 CA ASN D 165 30.156 -15.690 76.036 1.00 61.39 C +ATOM 6969 C ASN D 165 30.365 -14.669 74.949 1.00 75.52 C +ATOM 6970 O ASN D 165 31.508 -14.355 74.600 1.00 98.40 O +ATOM 6971 CB ASN D 165 30.767 -15.163 77.312 1.00 60.30 C +ATOM 6972 CG ASN D 165 30.034 -13.946 77.813 1.00 71.08 C +ATOM 6973 OD1 ASN D 165 28.941 -13.608 77.333 1.00 44.98 O +ATOM 6974 ND2 ASN D 165 30.623 -13.266 78.779 1.00 93.95 N +ATOM 6975 N VAL D 166 29.262 -14.153 74.400 1.00 84.70 N +ATOM 6976 CA VAL D 166 29.298 -13.230 73.252 1.00 71.26 C +ATOM 6977 C VAL D 166 30.015 -11.971 73.623 1.00 71.67 C +ATOM 6978 O VAL D 166 30.808 -11.470 72.854 1.00 71.32 O +ATOM 6979 CB VAL D 166 27.879 -12.861 72.793 1.00 77.86 C +ATOM 6980 CG1 VAL D 166 27.842 -11.516 72.094 1.00 63.31 C +ATOM 6981 CG2 VAL D 166 27.310 -13.991 71.909 1.00119.00 C +ATOM 6982 N SER D 167 29.808 -11.539 74.860 1.00 85.18 N +ATOM 6983 CA SER D 167 30.330 -10.266 75.324 1.00 89.75 C +ATOM 6984 C SER D 167 31.847 -10.268 75.501 1.00 88.46 C +ATOM 6985 O SER D 167 32.442 -9.201 75.642 1.00 89.45 O +ATOM 6986 CB SER D 167 29.631 -9.876 76.624 1.00 98.00 C +ATOM 6987 OG SER D 167 28.227 -10.105 76.520 1.00151.03 O +ATOM 6988 N THR D 168 32.477 -11.450 75.492 1.00 84.99 N +ATOM 6989 CA THR D 168 33.923 -11.550 75.731 1.00 90.16 C +ATOM 6990 C THR D 168 34.665 -12.521 74.798 1.00 76.78 C +ATOM 6991 O THR D 168 35.852 -12.363 74.506 1.00 63.22 O +ATOM 6992 CB THR D 168 34.219 -11.949 77.196 1.00103.95 C +ATOM 6993 OG1 THR D 168 33.473 -13.128 77.540 1.00117.01 O +ATOM 6994 CG2 THR D 168 33.862 -10.806 78.159 1.00103.40 C +ATOM 6995 N GLY D 169 34.011 -13.603 74.455 1.00 70.49 N +ATOM 6996 CA GLY D 169 34.722 -14.667 73.798 1.00 79.75 C +ATOM 6997 C GLY D 169 35.305 -15.684 74.755 1.00108.92 C +ATOM 6998 O GLY D 169 35.662 -16.793 74.334 1.00182.60 O +ATOM 6999 N GLU D 170 35.254 -15.400 76.056 1.00121.48 N +ATOM 7000 CA GLU D 170 35.472 -16.438 77.071 1.00133.92 C +ATOM 7001 C GLU D 170 34.525 -17.613 76.829 1.00128.07 C +ATOM 7002 O GLU D 170 33.332 -17.446 76.710 1.00 73.58 O +ATOM 7003 CB GLU D 170 35.253 -15.910 78.505 1.00141.96 C +ATOM 7004 CG GLU D 170 36.381 -15.021 79.028 1.00150.11 C +ATOM 7005 CD GLU D 170 35.916 -13.866 79.906 1.00151.66 C +ATOM 7006 OE1 GLU D 170 34.695 -13.604 79.956 1.00160.51 O +ATOM 7007 OE2 GLU D 170 36.777 -13.170 80.487 1.00145.65 O +ATOM 7008 N ILE D 171 35.073 -18.815 76.733 1.00141.59 N +ATOM 7009 CA ILE D 171 34.257 -20.001 76.835 1.00135.51 C +ATOM 7010 C ILE D 171 33.808 -20.156 78.295 1.00132.97 C +ATOM 7011 O ILE D 171 34.628 -20.144 79.200 1.00114.89 O +ATOM 7012 CB ILE D 171 35.037 -21.236 76.388 1.00128.51 C +ATOM 7013 CG1 ILE D 171 35.255 -21.166 74.882 1.00115.91 C +ATOM 7014 CG2 ILE D 171 34.288 -22.498 76.790 1.00140.30 C +ATOM 7015 CD1 ILE D 171 36.331 -22.118 74.409 1.00135.89 C +ATOM 7016 N LEU D 172 32.503 -20.243 78.518 1.00113.90 N +ATOM 7017 CA LEU D 172 31.976 -20.311 79.873 1.00 90.84 C +ATOM 7018 C LEU D 172 31.765 -21.760 80.346 1.00100.87 C +ATOM 7019 O LEU D 172 31.555 -22.040 81.549 1.00 89.04 O +ATOM 7020 CB LEU D 172 30.669 -19.547 79.977 1.00 97.03 C +ATOM 7021 CG LEU D 172 30.815 -18.008 79.868 1.00107.84 C +ATOM 7022 CD1 LEU D 172 29.533 -17.170 80.112 1.00122.86 C +ATOM 7023 CD2 LEU D 172 31.981 -17.464 80.668 1.00 85.86 C +ATOM 7024 N SER D 173 31.850 -22.692 79.404 1.00 91.83 N +ATOM 7025 CA SER D 173 31.721 -24.097 79.724 1.00105.32 C +ATOM 7026 C SER D 173 32.088 -24.947 78.519 1.00108.15 C +ATOM 7027 O SER D 173 31.545 -24.767 77.430 1.00126.35 O +ATOM 7028 CB SER D 173 30.280 -24.409 80.160 1.00123.99 C +ATOM 7029 OG SER D 173 30.027 -25.815 80.139 1.00160.48 O +ATOM 7030 N SER D 174 32.884 -25.978 78.746 1.00117.65 N +ATOM 7031 CA SER D 174 33.055 -27.041 77.746 1.00140.63 C +ATOM 7032 C SER D 174 32.666 -28.382 78.356 1.00139.70 C +ATOM 7033 O SER D 174 33.054 -28.689 79.486 1.00211.76 O +ATOM 7034 CB SER D 174 34.513 -27.084 77.251 1.00147.58 C +ATOM 7035 OG SER D 174 34.691 -27.925 76.117 1.00119.68 O +ATOM 7036 N VAL D 175 31.949 -29.202 77.590 1.00115.75 N +ATOM 7037 CA VAL D 175 31.585 -30.552 78.032 1.00107.98 C +ATOM 7038 C VAL D 175 31.764 -31.610 76.941 1.00104.02 C +ATOM 7039 O VAL D 175 31.584 -31.336 75.744 1.00109.40 O +ATOM 7040 CB VAL D 175 30.127 -30.596 78.507 1.00121.71 C +ATOM 7041 CG1 VAL D 175 29.937 -29.689 79.707 1.00118.70 C +ATOM 7042 CG2 VAL D 175 29.186 -30.178 77.399 1.00133.45 C +ATOM 7043 N ASN D 176 32.155 -32.817 77.353 1.00100.82 N +ATOM 7044 CA ASN D 176 32.564 -33.885 76.413 1.00108.83 C +ATOM 7045 C ASN D 176 31.796 -35.178 76.677 1.00 71.66 C +ATOM 7046 O ASN D 176 32.233 -35.981 77.470 1.00 83.38 O +ATOM 7047 CB ASN D 176 34.086 -34.147 76.555 1.00109.39 C +ATOM 7048 CG ASN D 176 34.941 -33.435 75.493 1.00116.82 C +ATOM 7049 OD1 ASN D 176 36.145 -33.729 75.285 1.00127.65 O +ATOM 7050 ND2 ASN D 176 34.319 -32.495 74.812 1.00114.32 N +ATOM 7051 N THR D 177 30.683 -35.395 75.985 1.00 72.46 N +ATOM 7052 CA THR D 177 29.857 -36.592 76.197 1.00 81.62 C +ATOM 7053 C THR D 177 30.222 -37.705 75.218 1.00 96.40 C +ATOM 7054 O THR D 177 30.768 -37.445 74.139 1.00122.65 O +ATOM 7055 CB THR D 177 28.342 -36.271 76.101 1.00 82.92 C +ATOM 7056 OG1 THR D 177 27.998 -35.955 74.752 1.00 79.05 O +ATOM 7057 CG2 THR D 177 27.986 -35.084 76.984 1.00 93.53 C +ATOM 7058 N SER D 178 29.846 -38.932 75.567 1.00111.57 N +ATOM 7059 CA SER D 178 30.141 -40.108 74.736 1.00130.38 C +ATOM 7060 C SER D 178 29.037 -41.166 74.831 1.00139.17 C +ATOM 7061 O SER D 178 28.296 -41.235 75.808 1.00103.33 O +ATOM 7062 CB SER D 178 31.462 -40.741 75.154 1.00122.54 C +ATOM 7063 OG SER D 178 31.607 -42.041 74.590 1.00 97.93 O +ATOM 7064 N LYS D 179 28.923 -41.986 73.792 1.00147.92 N +ATOM 7065 CA LYS D 179 27.809 -42.918 73.701 1.00128.36 C +ATOM 7066 C LYS D 179 28.193 -44.098 72.808 1.00121.65 C +ATOM 7067 O LYS D 179 28.911 -43.954 71.815 1.00 89.73 O +ATOM 7068 CB LYS D 179 26.560 -42.199 73.175 1.00103.17 C +ATOM 7069 CG LYS D 179 25.259 -42.656 73.778 1.00 87.51 C +ATOM 7070 CD LYS D 179 24.635 -43.724 72.914 1.00 98.91 C +ATOM 7071 CE LYS D 179 23.425 -44.321 73.600 1.00127.97 C +ATOM 7072 NZ LYS D 179 22.976 -45.571 72.931 1.00144.16 N +ATOM 7073 N THR D 180 27.706 -45.269 73.190 1.00116.81 N +ATOM 7074 CA THR D 180 28.061 -46.495 72.516 1.00132.05 C +ATOM 7075 C THR D 180 26.890 -47.031 71.664 1.00167.74 C +ATOM 7076 O THR D 180 25.731 -47.076 72.111 1.00 92.17 O +ATOM 7077 CB THR D 180 28.538 -47.575 73.508 1.00136.60 C +ATOM 7078 OG1 THR D 180 28.335 -48.868 72.922 1.00170.25 O +ATOM 7079 CG2 THR D 180 27.790 -47.479 74.830 1.00122.50 C +ATOM 7080 N ILE D 181 27.202 -47.389 70.416 1.00193.62 N +ATOM 7081 CA ILE D 181 26.201 -47.928 69.490 1.00171.19 C +ATOM 7082 C ILE D 181 26.293 -49.454 69.449 1.00142.35 C +ATOM 7083 O ILE D 181 27.319 -50.011 69.032 1.00117.57 O +ATOM 7084 CB ILE D 181 26.377 -47.338 68.069 1.00172.48 C +ATOM 7085 CG1 ILE D 181 26.396 -45.807 68.123 1.00181.54 C +ATOM 7086 CG2 ILE D 181 25.258 -47.776 67.138 1.00173.92 C +ATOM 7087 CD1 ILE D 181 27.684 -45.204 67.614 1.00218.30 C +ATOM 7088 N LEU D 182 25.219 -50.114 69.879 1.00116.31 N +ATOM 7089 CA LEU D 182 25.164 -51.585 69.946 1.00122.64 C +ATOM 7090 C LEU D 182 24.595 -52.289 68.696 1.00 96.64 C +ATOM 7091 O LEU D 182 23.613 -51.819 68.102 1.00108.05 O +ATOM 7092 CB LEU D 182 24.319 -52.006 71.135 1.00120.71 C +ATOM 7093 CG LEU D 182 24.166 -53.516 71.324 1.00128.14 C +ATOM 7094 CD1 LEU D 182 25.495 -54.227 71.585 1.00133.17 C +ATOM 7095 CD2 LEU D 182 23.183 -53.746 72.459 1.00143.23 C +ATOM 7096 N SER D 183 25.218 -53.408 68.321 1.00 65.71 N +ATOM 7097 CA SER D 183 24.766 -54.215 67.216 1.00 81.18 C +ATOM 7098 C SER D 183 24.928 -55.678 67.570 1.00121.07 C +ATOM 7099 O SER D 183 25.922 -56.077 68.177 1.00140.55 O +ATOM 7100 CB SER D 183 25.557 -53.908 65.935 1.00106.29 C +ATOM 7101 OG SER D 183 25.836 -52.513 65.813 1.00183.22 O +ATOM 7102 N TYR D 184 23.951 -56.494 67.184 1.00183.94 N +ATOM 7103 CA TYR D 184 24.042 -57.939 67.399 1.00166.80 C +ATOM 7104 C TYR D 184 23.289 -58.769 66.361 1.00164.39 C +ATOM 7105 O TYR D 184 22.302 -58.324 65.765 1.00143.19 O +ATOM 7106 CB TYR D 184 23.603 -58.303 68.820 1.00154.75 C +ATOM 7107 CG TYR D 184 22.189 -57.874 69.147 1.00142.06 C +ATOM 7108 CD1 TYR D 184 21.105 -58.675 68.819 1.00131.89 C +ATOM 7109 CD2 TYR D 184 21.944 -56.668 69.800 1.00135.06 C +ATOM 7110 CE1 TYR D 184 19.819 -58.289 69.142 1.00141.03 C +ATOM 7111 CE2 TYR D 184 20.659 -56.269 70.120 1.00115.28 C +ATOM 7112 CZ TYR D 184 19.603 -57.074 69.786 1.00124.05 C +ATOM 7113 OH TYR D 184 18.333 -56.714 70.151 1.00107.44 O +ATOM 7114 N GLU D 185 23.763 -60.001 66.199 1.00201.18 N +ATOM 7115 CA GLU D 185 23.227 -60.951 65.233 1.00213.34 C +ATOM 7116 C GLU D 185 23.012 -62.323 65.865 1.00221.76 C +ATOM 7117 O GLU D 185 23.965 -63.008 66.216 1.00231.12 O +ATOM 7118 CB GLU D 185 24.147 -61.116 64.022 1.00180.81 C +ATOM 7119 CG GLU D 185 24.770 -59.843 63.486 1.00159.43 C +ATOM 7120 CD GLU D 185 25.497 -60.093 62.182 1.00180.06 C +ATOM 7121 OE1 GLU D 185 25.527 -61.265 61.722 1.00217.78 O +ATOM 7122 OE2 GLU D 185 25.983 -59.118 61.583 1.00157.85 O +ATOM 7123 N VAL D 186 21.750 -62.705 66.004 1.00191.74 N +ATOM 7124 CA VAL D 186 21.379 -64.000 66.532 1.00176.11 C +ATOM 7125 C VAL D 186 20.976 -64.921 65.390 1.00157.58 C +ATOM 7126 O VAL D 186 20.298 -64.513 64.448 1.00161.07 O +ATOM 7127 CB VAL D 186 20.214 -63.876 67.530 1.00175.95 C +ATOM 7128 CG1 VAL D 186 19.969 -65.209 68.223 1.00200.27 C +ATOM 7129 CG2 VAL D 186 20.502 -62.790 68.553 1.00158.69 C +ATOM 7130 N GLN D 187 21.384 -66.176 65.474 1.00152.99 N +ATOM 7131 CA GLN D 187 21.148 -67.080 64.381 1.00160.54 C +ATOM 7132 C GLN D 187 21.082 -68.557 64.842 1.00200.05 C +ATOM 7133 O GLN D 187 21.804 -68.983 65.761 1.00266.98 O +ATOM 7134 CB GLN D 187 22.201 -66.813 63.323 1.00158.05 C +ATOM 7135 CG GLN D 187 22.125 -67.751 62.159 1.00155.85 C +ATOM 7136 CD GLN D 187 23.232 -67.502 61.168 1.00163.23 C +ATOM 7137 OE1 GLN D 187 24.327 -67.096 61.543 1.00160.87 O +ATOM 7138 NE2 GLN D 187 22.933 -67.678 59.887 1.00189.98 N +ATOM 7139 N ALA D 188 20.123 -69.303 64.294 1.00200.42 N +ATOM 7140 CA ALA D 188 19.950 -70.716 64.651 1.00186.88 C +ATOM 7141 C ALA D 188 19.598 -71.534 63.415 1.00189.45 C +ATOM 7142 O ALA D 188 18.836 -71.083 62.567 1.00213.80 O +ATOM 7143 CB ALA D 188 18.879 -70.880 65.725 1.00164.16 C +ATOM 7144 N GLY D 189 20.168 -72.728 63.308 1.00191.03 N +ATOM 7145 CA GLY D 189 19.921 -73.589 62.155 1.00190.66 C +ATOM 7146 C GLY D 189 19.915 -75.064 62.509 1.00225.14 C +ATOM 7147 O GLY D 189 20.723 -75.521 63.321 1.00287.80 O +ATOM 7148 N VAL D 190 18.987 -75.809 61.916 1.00225.76 N +ATOM 7149 CA VAL D 190 18.924 -77.260 62.098 1.00193.06 C +ATOM 7150 C VAL D 190 19.258 -77.950 60.768 1.00192.26 C +ATOM 7151 O VAL D 190 18.744 -77.562 59.709 1.00184.64 O +ATOM 7152 CB VAL D 190 17.531 -77.700 62.604 1.00163.05 C +ATOM 7153 CG1 VAL D 190 17.559 -79.156 63.034 1.00143.20 C +ATOM 7154 CG2 VAL D 190 17.057 -76.795 63.743 1.00137.74 C +ATOM 7155 N PHE D 191 20.118 -78.968 60.821 1.00199.20 N +ATOM 7156 CA PHE D 191 20.628 -79.581 59.581 1.00203.98 C +ATOM 7157 C PHE D 191 20.672 -81.124 59.650 1.00214.35 C +ATOM 7158 O PHE D 191 20.909 -81.732 60.703 1.00203.15 O +ATOM 7159 CB PHE D 191 21.987 -79.040 59.155 1.00183.77 C +ATOM 7160 CG PHE D 191 22.256 -77.604 59.530 1.00199.76 C +ATOM 7161 CD1 PHE D 191 21.786 -76.557 58.760 1.00197.34 C +ATOM 7162 CD2 PHE D 191 23.028 -77.306 60.642 1.00216.02 C +ATOM 7163 CE1 PHE D 191 22.046 -75.240 59.113 1.00196.19 C +ATOM 7164 CE2 PHE D 191 23.283 -75.992 61.007 1.00208.84 C +ATOM 7165 CZ PHE D 191 22.780 -74.957 60.247 1.00199.73 C +ATOM 7166 N ARG D 192 20.380 -81.744 58.514 1.00222.58 N +ATOM 7167 CA ARG D 192 20.688 -83.144 58.270 1.00211.37 C +ATOM 7168 C ARG D 192 20.848 -83.403 56.759 1.00229.81 C +ATOM 7169 O ARG D 192 19.899 -83.770 56.042 1.00247.04 O +ATOM 7170 CB ARG D 192 19.636 -84.067 58.871 1.00197.97 C +ATOM 7171 CG ARG D 192 20.136 -85.501 58.990 1.00174.26 C +ATOM 7172 CD ARG D 192 19.221 -86.356 59.856 1.00174.42 C +ATOM 7173 NE ARG D 192 17.815 -86.360 59.441 1.00163.82 N +ATOM 7174 CZ ARG D 192 17.349 -87.119 58.461 1.00168.13 C +ATOM 7175 NH1 ARG D 192 18.185 -87.891 57.787 1.00190.12 N +ATOM 7176 NH2 ARG D 192 16.063 -87.085 58.135 1.00154.07 N +ATOM 7177 N LEU D 200 17.213 -82.464 55.237 1.00105.90 N +ATOM 7178 CA LEU D 200 16.536 -81.459 56.057 1.00133.81 C +ATOM 7179 C LEU D 200 17.488 -80.349 56.475 1.00175.73 C +ATOM 7180 O LEU D 200 18.412 -80.573 57.274 1.00209.12 O +ATOM 7181 CB LEU D 200 15.927 -82.075 57.327 1.00120.37 C +ATOM 7182 CG LEU D 200 15.375 -81.044 58.333 1.00115.06 C +ATOM 7183 CD1 LEU D 200 13.858 -80.947 58.207 1.00118.31 C +ATOM 7184 CD2 LEU D 200 15.798 -81.321 59.775 1.00 96.82 C +ATOM 7185 N GLU D 201 17.225 -79.143 55.976 1.00197.43 N +ATOM 7186 CA GLU D 201 17.793 -77.930 56.561 1.00192.46 C +ATOM 7187 C GLU D 201 16.684 -76.974 56.998 1.00169.96 C +ATOM 7188 O GLU D 201 15.627 -76.931 56.382 1.00118.65 O +ATOM 7189 CB GLU D 201 18.714 -77.235 55.558 1.00188.48 C +ATOM 7190 CG GLU D 201 19.685 -76.268 56.209 1.00186.37 C +ATOM 7191 CD GLU D 201 20.598 -75.573 55.207 1.00191.15 C +ATOM 7192 OE1 GLU D 201 21.233 -76.264 54.386 1.00182.88 O +ATOM 7193 OE2 GLU D 201 20.730 -74.334 55.287 1.00186.62 O +ATOM 7194 N GLY D 202 16.942 -76.202 58.053 1.00164.50 N +ATOM 7195 CA GLY D 202 16.048 -75.122 58.474 1.00172.39 C +ATOM 7196 C GLY D 202 16.785 -74.043 59.256 1.00177.24 C +ATOM 7197 O GLY D 202 17.494 -74.347 60.214 1.00206.84 O +ATOM 7198 N GLU D 203 16.641 -72.784 58.843 1.00161.29 N +ATOM 7199 CA GLU D 203 17.392 -71.685 59.454 1.00155.50 C +ATOM 7200 C GLU D 203 16.537 -70.480 59.840 1.00137.33 C +ATOM 7201 O GLU D 203 15.673 -70.044 59.079 1.00178.33 O +ATOM 7202 CB GLU D 203 18.504 -71.228 58.513 1.00167.14 C +ATOM 7203 CG GLU D 203 19.598 -72.278 58.313 1.00194.25 C +ATOM 7204 CD GLU D 203 20.767 -71.802 57.456 1.00214.99 C +ATOM 7205 OE1 GLU D 203 20.681 -70.694 56.880 1.00242.18 O +ATOM 7206 OE2 GLU D 203 21.768 -72.549 57.336 1.00217.07 O +ATOM 7207 N VAL D 204 16.811 -69.938 61.023 1.00127.53 N +ATOM 7208 CA VAL D 204 16.246 -68.668 61.485 1.00151.78 C +ATOM 7209 C VAL D 204 17.391 -67.708 61.832 1.00170.09 C +ATOM 7210 O VAL D 204 18.366 -68.102 62.473 1.00160.23 O +ATOM 7211 CB VAL D 204 15.310 -68.875 62.712 1.00125.01 C +ATOM 7212 CG1 VAL D 204 15.011 -67.566 63.438 1.00109.94 C +ATOM 7213 CG2 VAL D 204 14.016 -69.537 62.267 1.00116.26 C +ATOM 7214 N GLY D 205 17.254 -66.449 61.417 1.00173.53 N +ATOM 7215 CA GLY D 205 18.214 -65.405 61.769 1.00153.04 C +ATOM 7216 C GLY D 205 17.549 -64.091 62.172 1.00128.64 C +ATOM 7217 O GLY D 205 16.450 -63.778 61.719 1.00134.64 O +ATOM 7218 N TYR D 206 18.233 -63.307 63.001 1.00112.47 N +ATOM 7219 CA TYR D 206 17.802 -61.951 63.353 1.00104.70 C +ATOM 7220 C TYR D 206 19.011 -61.057 63.610 1.00121.66 C +ATOM 7221 O TYR D 206 19.985 -61.496 64.209 1.00157.11 O +ATOM 7222 CB TYR D 206 16.924 -61.973 64.607 1.00 84.20 C +ATOM 7223 CG TYR D 206 16.493 -60.590 65.089 1.00 79.31 C +ATOM 7224 CD1 TYR D 206 15.467 -59.891 64.450 1.00 81.05 C +ATOM 7225 CD2 TYR D 206 17.081 -60.003 66.201 1.00 80.55 C +ATOM 7226 CE1 TYR D 206 15.046 -58.647 64.903 1.00 83.84 C +ATOM 7227 CE2 TYR D 206 16.664 -58.759 66.667 1.00 91.82 C +ATOM 7228 CZ TYR D 206 15.651 -58.075 66.010 1.00 91.97 C +ATOM 7229 OH TYR D 206 15.258 -56.823 66.469 1.00 77.91 O +ATOM 7230 N THR D 207 18.940 -59.792 63.194 1.00121.46 N +ATOM 7231 CA THR D 207 20.026 -58.824 63.458 1.00101.04 C +ATOM 7232 C THR D 207 19.462 -57.472 63.900 1.00 83.59 C +ATOM 7233 O THR D 207 18.472 -56.985 63.331 1.00 90.17 O +ATOM 7234 CB THR D 207 20.919 -58.622 62.215 1.00 88.84 C +ATOM 7235 OG1 THR D 207 20.137 -58.091 61.149 1.00100.29 O +ATOM 7236 CG2 THR D 207 21.513 -59.929 61.766 1.00 96.72 C +ATOM 7237 N SER D 208 20.068 -56.870 64.921 1.00 81.03 N +ATOM 7238 CA SER D 208 19.635 -55.536 65.385 1.00120.90 C +ATOM 7239 C SER D 208 20.789 -54.549 65.548 1.00139.15 C +ATOM 7240 O SER D 208 21.762 -54.847 66.229 1.00147.36 O +ATOM 7241 CB SER D 208 18.861 -55.621 66.700 1.00108.12 C +ATOM 7242 OG SER D 208 18.581 -54.312 67.204 1.00 76.37 O +ATOM 7243 N ASN D 209 20.661 -53.392 64.887 1.00124.57 N +ATOM 7244 CA ASN D 209 21.587 -52.287 65.026 1.00 83.15 C +ATOM 7245 C ASN D 209 20.896 -51.141 65.721 1.00 89.58 C +ATOM 7246 O ASN D 209 19.774 -50.763 65.365 1.00 96.95 O +ATOM 7247 CB ASN D 209 22.063 -51.802 63.661 1.00 70.19 C +ATOM 7248 CG ASN D 209 22.959 -52.780 62.986 1.00 71.75 C +ATOM 7249 OD1 ASN D 209 24.168 -52.861 63.289 1.00125.33 O +ATOM 7250 ND2 ASN D 209 22.398 -53.547 62.071 1.00 63.23 N +ATOM 7251 N GLU D 210 21.591 -50.524 66.661 1.00 94.51 N +ATOM 7252 CA GLU D 210 21.166 -49.218 67.150 1.00125.64 C +ATOM 7253 C GLU D 210 21.298 -48.179 66.011 1.00128.24 C +ATOM 7254 O GLU D 210 22.262 -48.209 65.244 1.00147.12 O +ATOM 7255 CB GLU D 210 22.015 -48.805 68.360 1.00135.01 C +ATOM 7256 CG GLU D 210 21.233 -48.236 69.530 1.00115.97 C +ATOM 7257 CD GLU D 210 22.045 -48.244 70.819 1.00114.26 C +ATOM 7258 OE1 GLU D 210 22.974 -49.078 70.990 1.00 73.15 O +ATOM 7259 OE2 GLU D 210 21.742 -47.385 71.674 1.00140.08 O +ATOM 7260 N PRO D 211 20.329 -47.262 65.893 1.00 98.40 N +ATOM 7261 CA PRO D 211 20.527 -46.133 65.003 1.00111.97 C +ATOM 7262 C PRO D 211 21.613 -45.160 65.524 1.00130.11 C +ATOM 7263 O PRO D 211 21.510 -44.643 66.648 1.00124.37 O +ATOM 7264 CB PRO D 211 19.136 -45.466 64.958 1.00 79.79 C +ATOM 7265 CG PRO D 211 18.214 -46.485 65.477 1.00 76.77 C +ATOM 7266 CD PRO D 211 19.003 -47.233 66.508 1.00 81.28 C +ATOM 7267 N VAL D 212 22.627 -44.908 64.697 1.00111.29 N +ATOM 7268 CA VAL D 212 23.662 -43.941 65.021 1.00 98.09 C +ATOM 7269 C VAL D 212 23.038 -42.558 65.182 1.00 88.76 C +ATOM 7270 O VAL D 212 23.396 -41.774 66.078 1.00129.80 O +ATOM 7271 CB VAL D 212 24.729 -43.878 63.905 1.00110.30 C +ATOM 7272 CG1 VAL D 212 25.893 -42.973 64.334 1.00118.96 C +ATOM 7273 CG2 VAL D 212 25.236 -45.275 63.545 1.00 97.76 C +ATOM 7274 N MET D 213 22.159 -42.238 64.244 1.00 77.49 N +ATOM 7275 CA MET D 213 21.211 -41.138 64.348 1.00 95.65 C +ATOM 7276 C MET D 213 20.716 -40.855 65.789 1.00 95.38 C +ATOM 7277 O MET D 213 20.747 -39.716 66.294 1.00 77.73 O +ATOM 7278 CB MET D 213 20.046 -41.551 63.445 1.00104.46 C +ATOM 7279 CG MET D 213 18.931 -40.564 63.245 1.00135.18 C +ATOM 7280 SD MET D 213 17.743 -41.308 62.128 1.00155.54 S +ATOM 7281 CE MET D 213 16.442 -41.599 63.318 1.00189.01 C +ATOM 7282 N LEU D 214 20.257 -41.912 66.441 1.00 99.96 N +ATOM 7283 CA LEU D 214 19.495 -41.790 67.670 1.00108.61 C +ATOM 7284 C LEU D 214 20.468 -41.648 68.828 1.00101.23 C +ATOM 7285 O LEU D 214 20.151 -41.065 69.867 1.00117.89 O +ATOM 7286 CB LEU D 214 18.590 -43.023 67.837 1.00128.75 C +ATOM 7287 CG LEU D 214 17.153 -42.831 68.333 1.00148.27 C +ATOM 7288 CD1 LEU D 214 16.338 -41.932 67.413 1.00146.73 C +ATOM 7289 CD2 LEU D 214 16.473 -44.191 68.476 1.00164.97 C +ATOM 7290 N CYS D 215 21.646 -42.243 68.666 1.00106.04 N +ATOM 7291 CA CYS D 215 22.695 -42.177 69.693 1.00128.94 C +ATOM 7292 C CYS D 215 23.283 -40.772 69.741 1.00132.78 C +ATOM 7293 O CYS D 215 23.598 -40.223 70.808 1.00 85.36 O +ATOM 7294 CB CYS D 215 23.807 -43.183 69.375 1.00123.02 C +ATOM 7295 SG CYS D 215 23.283 -44.899 69.483 1.00157.99 S +ATOM 7296 N LEU D 216 23.479 -40.219 68.548 1.00150.48 N +ATOM 7297 CA LEU D 216 23.935 -38.853 68.427 1.00134.08 C +ATOM 7298 C LEU D 216 22.958 -37.953 69.172 1.00115.33 C +ATOM 7299 O LEU D 216 23.371 -37.105 69.970 1.00149.87 O +ATOM 7300 CB LEU D 216 24.045 -38.445 66.948 1.00147.02 C +ATOM 7301 CG LEU D 216 24.474 -36.995 66.691 1.00132.99 C +ATOM 7302 CD1 LEU D 216 25.813 -36.661 67.344 1.00127.62 C +ATOM 7303 CD2 LEU D 216 24.539 -36.715 65.205 1.00112.37 C +ATOM 7304 N MET D 217 21.666 -38.147 68.913 1.00 95.21 N +ATOM 7305 CA MET D 217 20.652 -37.281 69.478 1.00 92.06 C +ATOM 7306 C MET D 217 20.667 -37.390 71.003 1.00126.66 C +ATOM 7307 O MET D 217 20.695 -36.374 71.709 1.00138.55 O +ATOM 7308 CB MET D 217 19.274 -37.630 68.920 1.00 86.30 C +ATOM 7309 CG MET D 217 18.441 -36.403 68.574 1.00 86.74 C +ATOM 7310 SD MET D 217 17.917 -35.474 70.045 1.00144.42 S +ATOM 7311 CE MET D 217 17.220 -33.982 69.329 1.00117.65 C +ATOM 7312 N SER D 218 20.717 -38.624 71.502 1.00144.73 N +ATOM 7313 CA SER D 218 20.786 -38.888 72.939 1.00134.60 C +ATOM 7314 C SER D 218 21.971 -38.166 73.592 1.00143.60 C +ATOM 7315 O SER D 218 21.818 -37.471 74.613 1.00147.74 O +ATOM 7316 CB SER D 218 20.913 -40.390 73.187 1.00140.81 C +ATOM 7317 OG SER D 218 20.751 -40.695 74.566 1.00174.21 O +ATOM 7318 N ALA D 219 23.154 -38.340 73.009 1.00125.44 N +ATOM 7319 CA ALA D 219 24.374 -37.772 73.583 1.00120.03 C +ATOM 7320 C ALA D 219 24.347 -36.221 73.618 1.00 99.62 C +ATOM 7321 O ALA D 219 24.855 -35.587 74.545 1.00 78.57 O +ATOM 7322 CB ALA D 219 25.577 -38.280 72.808 1.00115.92 C +ATOM 7323 N ILE D 220 23.718 -35.621 72.616 1.00 99.25 N +ATOM 7324 CA ILE D 220 23.613 -34.167 72.553 1.00 96.21 C +ATOM 7325 C ILE D 220 22.706 -33.670 73.674 1.00107.24 C +ATOM 7326 O ILE D 220 22.989 -32.653 74.312 1.00 82.79 O +ATOM 7327 CB ILE D 220 23.100 -33.689 71.166 1.00101.16 C +ATOM 7328 CG1 ILE D 220 24.189 -33.925 70.108 1.00 94.16 C +ATOM 7329 CG2 ILE D 220 22.695 -32.218 71.208 1.00 84.59 C +ATOM 7330 CD1 ILE D 220 23.688 -33.871 68.687 1.00109.47 C +ATOM 7331 N GLU D 221 21.603 -34.377 73.906 1.00138.75 N +ATOM 7332 CA GLU D 221 20.687 -34.030 75.005 1.00154.25 C +ATOM 7333 C GLU D 221 21.436 -34.037 76.345 1.00133.55 C +ATOM 7334 O GLU D 221 21.383 -33.068 77.109 1.00 91.61 O +ATOM 7335 CB GLU D 221 19.509 -35.016 75.044 1.00163.99 C +ATOM 7336 CG GLU D 221 18.489 -34.805 73.934 1.00170.96 C +ATOM 7337 CD GLU D 221 17.564 -35.998 73.719 1.00172.71 C +ATOM 7338 OE1 GLU D 221 18.015 -37.172 73.837 1.00118.44 O +ATOM 7339 OE2 GLU D 221 16.386 -35.737 73.383 1.00150.65 O +ATOM 7340 N THR D 222 22.138 -35.143 76.596 1.00115.68 N +ATOM 7341 CA THR D 222 22.959 -35.324 77.793 1.00 97.30 C +ATOM 7342 C THR D 222 23.914 -34.153 77.972 1.00106.23 C +ATOM 7343 O THR D 222 24.025 -33.601 79.067 1.00 95.15 O +ATOM 7344 CB THR D 222 23.787 -36.619 77.676 1.00101.05 C +ATOM 7345 OG1 THR D 222 22.918 -37.762 77.795 1.00104.60 O +ATOM 7346 CG2 THR D 222 24.925 -36.660 78.714 1.00 87.32 C +ATOM 7347 N GLY D 223 24.608 -33.795 76.888 1.00113.43 N +ATOM 7348 CA GLY D 223 25.503 -32.638 76.879 1.00 99.52 C +ATOM 7349 C GLY D 223 24.811 -31.342 77.264 1.00 89.77 C +ATOM 7350 O GLY D 223 25.362 -30.540 78.036 1.00 96.17 O +ATOM 7351 N VAL D 224 23.572 -31.164 76.799 1.00 66.37 N +ATOM 7352 CA VAL D 224 22.818 -29.966 77.130 1.00 82.87 C +ATOM 7353 C VAL D 224 22.526 -29.912 78.633 1.00105.86 C +ATOM 7354 O VAL D 224 22.662 -28.856 79.269 1.00 92.62 O +ATOM 7355 CB VAL D 224 21.492 -29.880 76.358 1.00 91.74 C +ATOM 7356 CG1 VAL D 224 20.659 -28.703 76.860 1.00 93.07 C +ATOM 7357 CG2 VAL D 224 21.755 -29.744 74.870 1.00 88.28 C +ATOM 7358 N ILE D 225 22.166 -31.054 79.207 1.00134.24 N +ATOM 7359 CA ILE D 225 21.918 -31.120 80.645 1.00139.87 C +ATOM 7360 C ILE D 225 23.175 -30.743 81.424 1.00130.88 C +ATOM 7361 O ILE D 225 23.112 -29.862 82.285 1.00101.21 O +ATOM 7362 CB ILE D 225 21.426 -32.511 81.086 1.00159.64 C +ATOM 7363 CG1 ILE D 225 20.029 -32.780 80.523 1.00168.80 C +ATOM 7364 CG2 ILE D 225 21.371 -32.595 82.601 1.00161.03 C +ATOM 7365 CD1 ILE D 225 19.639 -34.242 80.534 1.00175.41 C +ATOM 7366 N PHE D 226 24.304 -31.401 81.121 1.00116.61 N +ATOM 7367 CA PHE D 226 25.577 -31.099 81.785 1.00116.59 C +ATOM 7368 C PHE D 226 25.944 -29.612 81.670 1.00118.10 C +ATOM 7369 O PHE D 226 26.542 -29.032 82.577 1.00115.55 O +ATOM 7370 CB PHE D 226 26.725 -31.951 81.222 1.00124.48 C +ATOM 7371 CG PHE D 226 26.790 -33.360 81.774 1.00130.86 C +ATOM 7372 CD1 PHE D 226 26.985 -33.589 83.134 1.00125.05 C +ATOM 7373 CD2 PHE D 226 26.774 -34.453 80.912 1.00131.75 C +ATOM 7374 CE1 PHE D 226 27.061 -34.876 83.632 1.00127.09 C +ATOM 7375 CE2 PHE D 226 26.914 -35.740 81.391 1.00124.97 C +ATOM 7376 CZ PHE D 226 27.014 -35.957 82.760 1.00154.34 C +ATOM 7377 N LEU D 227 25.596 -29.001 80.547 1.00127.65 N +ATOM 7378 CA LEU D 227 25.827 -27.579 80.348 1.00130.59 C +ATOM 7379 C LEU D 227 24.974 -26.742 81.283 1.00107.55 C +ATOM 7380 O LEU D 227 25.475 -25.777 81.874 1.00166.33 O +ATOM 7381 CB LEU D 227 25.544 -27.205 78.891 1.00135.65 C +ATOM 7382 CG LEU D 227 26.630 -27.588 77.866 1.00116.02 C +ATOM 7383 CD1 LEU D 227 26.206 -27.486 76.420 1.00114.67 C +ATOM 7384 CD2 LEU D 227 27.885 -26.777 78.071 1.00117.19 C +ATOM 7385 N ILE D 228 23.703 -27.098 81.416 1.00 92.70 N +ATOM 7386 CA ILE D 228 22.793 -26.329 82.263 1.00127.80 C +ATOM 7387 C ILE D 228 23.238 -26.454 83.718 1.00143.30 C +ATOM 7388 O ILE D 228 23.330 -25.456 84.439 1.00149.31 O +ATOM 7389 CB ILE D 228 21.322 -26.794 82.146 1.00119.80 C +ATOM 7390 CG1 ILE D 228 20.784 -26.551 80.739 1.00128.22 C +ATOM 7391 CG2 ILE D 228 20.446 -26.033 83.131 1.00 94.11 C +ATOM 7392 CD1 ILE D 228 19.509 -27.303 80.420 1.00127.57 C +ATOM 7393 N ASN D 229 23.533 -27.680 84.134 1.00138.17 N +ATOM 7394 CA ASN D 229 23.948 -27.950 85.510 1.00131.10 C +ATOM 7395 C ASN D 229 25.245 -27.225 85.836 1.00115.67 C +ATOM 7396 O ASN D 229 25.353 -26.575 86.877 1.00120.79 O +ATOM 7397 CB ASN D 229 24.126 -29.456 85.713 1.00144.45 C +ATOM 7398 CG ASN D 229 24.168 -29.852 87.171 1.00148.69 C +ATOM 7399 OD1 ASN D 229 23.658 -29.142 88.042 1.00150.98 O +ATOM 7400 ND2 ASN D 229 24.768 -31.000 87.445 1.00162.26 N +ATOM 7401 N ASP D 230 26.195 -27.286 84.906 1.00103.17 N +ATOM 7402 CA ASP D 230 27.452 -26.557 85.031 1.00103.57 C +ATOM 7403 C ASP D 230 27.222 -25.041 85.159 1.00112.31 C +ATOM 7404 O ASP D 230 27.849 -24.367 85.979 1.00102.89 O +ATOM 7405 CB ASP D 230 28.352 -26.834 83.825 1.00103.27 C +ATOM 7406 CG ASP D 230 29.737 -26.236 83.980 1.00122.63 C +ATOM 7407 OD1 ASP D 230 30.514 -26.772 84.796 1.00185.86 O +ATOM 7408 OD2 ASP D 230 30.054 -25.225 83.321 1.00122.64 O +ATOM 7409 N GLY D 231 26.294 -24.511 84.368 1.00138.86 N +ATOM 7410 CA GLY D 231 25.980 -23.081 84.402 1.00154.00 C +ATOM 7411 C GLY D 231 25.293 -22.665 85.693 1.00154.34 C +ATOM 7412 O GLY D 231 25.539 -21.562 86.211 1.00177.86 O +ATOM 7413 N ILE D 232 24.478 -23.568 86.243 1.00145.15 N +ATOM 7414 CA ILE D 232 23.858 -23.352 87.557 1.00155.71 C +ATOM 7415 C ILE D 232 24.917 -23.225 88.653 1.00173.26 C +ATOM 7416 O ILE D 232 24.916 -22.251 89.406 1.00142.34 O +ATOM 7417 CB ILE D 232 22.889 -24.495 87.925 1.00152.92 C +ATOM 7418 CG1 ILE D 232 21.625 -24.389 87.067 1.00166.29 C +ATOM 7419 CG2 ILE D 232 22.540 -24.463 89.416 1.00134.44 C +ATOM 7420 CD1 ILE D 232 20.802 -25.656 87.029 1.00169.57 C +ATOM 7421 N ASP D 233 25.843 -24.186 88.692 1.00211.55 N +ATOM 7422 CA ASP D 233 26.981 -24.154 89.624 1.00195.84 C +ATOM 7423 C ASP D 233 27.795 -22.859 89.501 1.00203.91 C +ATOM 7424 O ASP D 233 28.066 -22.197 90.497 1.00229.13 O +ATOM 7425 CB ASP D 233 27.916 -25.354 89.391 1.00168.28 C +ATOM 7426 CG ASP D 233 27.250 -26.694 89.687 1.00142.88 C +ATOM 7427 OD1 ASP D 233 26.016 -26.726 89.899 1.00129.04 O +ATOM 7428 OD2 ASP D 233 27.968 -27.717 89.704 1.00131.67 O +ATOM 7429 N ARG D 234 28.155 -22.489 88.275 1.00216.08 N +ATOM 7430 CA ARG D 234 29.046 -21.348 88.041 1.00191.08 C +ATOM 7431 C ARG D 234 28.352 -19.980 88.074 1.00165.65 C +ATOM 7432 O ARG D 234 29.003 -18.948 87.901 1.00174.91 O +ATOM 7433 CB ARG D 234 29.778 -21.535 86.714 1.00192.58 C +ATOM 7434 CG ARG D 234 30.836 -22.611 86.806 1.00156.33 C +ATOM 7435 CD ARG D 234 31.209 -23.181 85.458 1.00146.78 C +ATOM 7436 NE ARG D 234 32.196 -24.232 85.698 1.00120.83 N +ATOM 7437 CZ ARG D 234 33.438 -24.228 85.231 1.00 90.72 C +ATOM 7438 NH1 ARG D 234 33.802 -23.286 84.382 1.00 93.66 N +ATOM 7439 NH2 ARG D 234 34.272 -25.201 85.551 1.00 69.21 N +ATOM 7440 N GLY D 235 27.038 -19.971 88.286 1.00131.88 N +ATOM 7441 CA GLY D 235 26.290 -18.727 88.408 1.00121.85 C +ATOM 7442 C GLY D 235 26.049 -18.022 87.086 1.00126.96 C +ATOM 7443 O GLY D 235 26.004 -16.788 87.037 1.00126.46 O +ATOM 7444 N LEU D 236 25.914 -18.787 86.002 1.00128.32 N +ATOM 7445 CA LEU D 236 25.454 -18.206 84.735 1.00130.15 C +ATOM 7446 C LEU D 236 23.963 -17.901 84.845 1.00130.22 C +ATOM 7447 O LEU D 236 23.511 -16.811 84.493 1.00 98.93 O +ATOM 7448 CB LEU D 236 25.711 -19.149 83.542 1.00136.11 C +ATOM 7449 CG LEU D 236 27.105 -19.134 82.890 1.00114.86 C +ATOM 7450 CD1 LEU D 236 28.093 -19.926 83.724 1.00 90.19 C +ATOM 7451 CD2 LEU D 236 27.033 -19.700 81.475 1.00120.77 C +ATOM 7452 N TRP D 237 23.201 -18.881 85.322 1.00156.39 N +ATOM 7453 CA TRP D 237 21.750 -18.747 85.439 1.00171.93 C +ATOM 7454 C TRP D 237 21.267 -19.365 86.752 1.00188.57 C +ATOM 7455 O TRP D 237 22.009 -20.117 87.402 1.00187.02 O +ATOM 7456 CB TRP D 237 21.059 -19.391 84.234 1.00162.56 C +ATOM 7457 CG TRP D 237 21.804 -20.580 83.710 1.00169.13 C +ATOM 7458 CD1 TRP D 237 21.987 -21.771 84.347 1.00183.98 C +ATOM 7459 CD2 TRP D 237 22.480 -20.691 82.452 1.00139.51 C +ATOM 7460 NE1 TRP D 237 22.733 -22.619 83.566 1.00174.91 N +ATOM 7461 CE2 TRP D 237 23.043 -21.987 82.392 1.00139.74 C +ATOM 7462 CE3 TRP D 237 22.636 -19.839 81.363 1.00124.28 C +ATOM 7463 CZ2 TRP D 237 23.784 -22.437 81.302 1.00111.37 C +ATOM 7464 CZ3 TRP D 237 23.359 -20.295 80.275 1.00141.05 C +ATOM 7465 CH2 TRP D 237 23.925 -21.586 80.257 1.00123.29 C +ATOM 7466 N ASP D 238 20.031 -19.043 87.137 1.00181.56 N +ATOM 7467 CA ASP D 238 19.500 -19.439 88.445 1.00190.89 C +ATOM 7468 C ASP D 238 18.137 -20.128 88.371 1.00183.95 C +ATOM 7469 O ASP D 238 17.314 -19.819 87.500 1.00147.61 O +ATOM 7470 CB ASP D 238 19.396 -18.229 89.370 1.00177.48 C +ATOM 7471 CG ASP D 238 20.717 -17.511 89.539 1.00164.44 C +ATOM 7472 OD1 ASP D 238 21.072 -16.732 88.636 1.00152.97 O +ATOM 7473 OD2 ASP D 238 21.396 -17.714 90.571 1.00177.16 O +ATOM 7474 N LEU D 239 17.904 -21.046 89.314 1.00164.95 N +ATOM 7475 CA LEU D 239 16.663 -21.808 89.372 1.00154.33 C +ATOM 7476 C LEU D 239 15.543 -20.954 89.940 1.00149.64 C +ATOM 7477 O LEU D 239 15.767 -20.114 90.814 1.00160.13 O +ATOM 7478 CB LEU D 239 16.831 -23.059 90.241 1.00153.47 C +ATOM 7479 CG LEU D 239 17.569 -24.272 89.678 1.00160.17 C +ATOM 7480 CD1 LEU D 239 17.518 -25.433 90.662 1.00176.44 C +ATOM 7481 CD2 LEU D 239 16.975 -24.697 88.353 1.00156.78 C +ATOM 7482 N GLN D 240 14.339 -21.159 89.416 1.00145.35 N +ATOM 7483 CA GLN D 240 13.137 -20.567 89.998 1.00130.66 C +ATOM 7484 C GLN D 240 13.040 -20.917 91.480 1.00141.58 C +ATOM 7485 O GLN D 240 12.971 -20.037 92.338 1.00135.83 O +ATOM 7486 CB GLN D 240 11.889 -21.065 89.256 1.00128.33 C +ATOM 7487 CG GLN D 240 10.606 -20.352 89.661 1.00128.06 C +ATOM 7488 CD GLN D 240 10.624 -18.882 89.283 1.00128.76 C +ATOM 7489 OE1 GLN D 240 10.372 -18.525 88.129 1.00132.85 O +ATOM 7490 NE2 GLN D 240 10.971 -18.024 90.240 1.00128.02 N +ATOM 7491 N ASN D 241 13.060 -22.215 91.763 1.00174.06 N +ATOM 7492 CA ASN D 241 12.994 -22.731 93.127 1.00179.34 C +ATOM 7493 C ASN D 241 14.350 -23.228 93.585 1.00190.95 C +ATOM 7494 O ASN D 241 14.837 -24.266 93.109 1.00223.62 O +ATOM 7495 CB ASN D 241 12.001 -23.885 93.199 1.00188.37 C +ATOM 7496 CG ASN D 241 10.671 -23.464 93.767 1.00203.27 C +ATOM 7497 OD1 ASN D 241 10.381 -23.738 94.926 1.00220.49 O +ATOM 7498 ND2 ASN D 241 9.853 -22.792 92.955 1.00213.43 N +ATOM 7499 N LYS D 242 14.940 -22.510 94.533 1.00168.11 N +ATOM 7500 CA LYS D 242 16.251 -22.878 95.048 1.00184.45 C +ATOM 7501 C LYS D 242 16.148 -24.210 95.782 1.00184.61 C +ATOM 7502 O LYS D 242 17.130 -24.964 95.871 1.00177.19 O +ATOM 7503 CB LYS D 242 16.800 -21.777 95.963 1.00185.14 C +ATOM 7504 CG LYS D 242 16.736 -20.380 95.354 1.00176.40 C +ATOM 7505 CD LYS D 242 18.092 -19.686 95.357 1.00166.95 C +ATOM 7506 CE LYS D 242 18.383 -19.048 94.005 1.00161.45 C +ATOM 7507 NZ LYS D 242 19.623 -18.231 94.016 1.00159.17 N +ATOM 7508 N ALA D 243 14.937 -24.492 96.269 1.00182.75 N +ATOM 7509 CA ALA D 243 14.596 -25.765 96.900 1.00198.19 C +ATOM 7510 C ALA D 243 14.745 -26.927 95.927 1.00215.93 C +ATOM 7511 O ALA D 243 14.832 -28.085 96.352 1.00246.17 O +ATOM 7512 CB ALA D 243 13.170 -25.722 97.442 1.00178.65 C +ATOM 7513 N GLU D 244 14.749 -26.629 94.626 1.00205.47 N +ATOM 7514 CA GLU D 244 14.822 -27.685 93.625 1.00188.43 C +ATOM 7515 C GLU D 244 16.250 -27.981 93.204 1.00150.94 C +ATOM 7516 O GLU D 244 16.455 -28.688 92.225 1.00150.54 O +ATOM 7517 CB GLU D 244 13.969 -27.338 92.399 1.00187.92 C +ATOM 7518 CG GLU D 244 12.470 -27.451 92.632 1.00180.59 C +ATOM 7519 CD GLU D 244 11.669 -27.362 91.343 1.00160.95 C +ATOM 7520 OE1 GLU D 244 11.496 -26.235 90.822 1.00119.99 O +ATOM 7521 OE2 GLU D 244 11.188 -28.416 90.871 1.00146.38 O +ATOM 7522 N ARG D 245 17.228 -27.441 93.928 1.00139.89 N +ATOM 7523 CA ARG D 245 18.634 -27.759 93.657 1.00177.08 C +ATOM 7524 C ARG D 245 18.928 -29.252 93.745 1.00189.69 C +ATOM 7525 O ARG D 245 19.747 -29.771 92.984 1.00148.82 O +ATOM 7526 CB ARG D 245 19.576 -27.027 94.599 1.00182.56 C +ATOM 7527 CG ARG D 245 21.055 -27.197 94.231 1.00179.84 C +ATOM 7528 CD ARG D 245 21.997 -26.373 95.130 1.00186.03 C +ATOM 7529 NE ARG D 245 22.389 -25.110 94.500 1.00180.16 N +ATOM 7530 CZ ARG D 245 23.226 -25.006 93.467 1.00166.09 C +ATOM 7531 NH1 ARG D 245 23.747 -26.084 92.913 1.00158.86 N +ATOM 7532 NH2 ARG D 245 23.526 -23.814 92.962 1.00170.50 N +ATOM 7533 N GLN D 246 18.270 -29.938 94.678 1.00212.54 N +ATOM 7534 CA GLN D 246 18.525 -31.364 94.891 1.00206.17 C +ATOM 7535 C GLN D 246 17.566 -32.246 94.093 1.00188.81 C +ATOM 7536 O GLN D 246 17.365 -33.411 94.419 1.00177.63 O +ATOM 7537 CB GLN D 246 18.454 -31.699 96.383 1.00185.23 C +ATOM 7538 CG GLN D 246 19.539 -30.997 97.195 1.00163.58 C +ATOM 7539 CD GLN D 246 20.938 -31.587 97.033 1.00178.30 C +ATOM 7540 OE1 GLN D 246 21.398 -31.839 95.920 1.00217.24 O +ATOM 7541 NE2 GLN D 246 21.641 -31.758 98.148 1.00173.05 N +ATOM 7542 N ASN D 247 16.983 -31.673 93.045 1.00167.01 N +ATOM 7543 CA ASN D 247 16.263 -32.432 92.029 1.00156.50 C +ATOM 7544 C ASN D 247 16.973 -33.738 91.668 1.00162.51 C +ATOM 7545 O ASN D 247 18.200 -33.758 91.498 1.00176.33 O +ATOM 7546 CB ASN D 247 16.128 -31.579 90.766 1.00176.50 C +ATOM 7547 CG ASN D 247 14.933 -31.962 89.938 1.00166.73 C +ATOM 7548 OD1 ASN D 247 15.069 -32.514 88.836 1.00187.44 O +ATOM 7549 ND2 ASN D 247 13.750 -31.634 90.441 1.00139.83 N +ATOM 7550 N ASP D 248 16.200 -34.813 91.509 1.00158.58 N +ATOM 7551 CA ASP D 248 16.761 -36.146 91.210 1.00182.33 C +ATOM 7552 C ASP D 248 17.701 -36.109 89.999 1.00201.56 C +ATOM 7553 O ASP D 248 18.803 -36.683 90.012 1.00187.30 O +ATOM 7554 CB ASP D 248 15.640 -37.159 90.918 1.00179.51 C +ATOM 7555 CG ASP D 248 14.847 -37.540 92.150 1.00178.70 C +ATOM 7556 OD1 ASP D 248 15.446 -37.676 93.243 1.00204.54 O +ATOM 7557 OD2 ASP D 248 13.619 -37.723 92.019 1.00156.30 O +ATOM 7558 N ILE D 249 17.233 -35.458 88.938 1.00199.35 N +ATOM 7559 CA ILE D 249 17.957 -35.406 87.679 1.00176.86 C +ATOM 7560 C ILE D 249 19.250 -34.604 87.860 1.00161.69 C +ATOM 7561 O ILE D 249 20.342 -35.061 87.496 1.00163.93 O +ATOM 7562 CB ILE D 249 17.080 -34.777 86.577 1.00168.91 C +ATOM 7563 CG1 ILE D 249 15.839 -35.644 86.317 1.00144.36 C +ATOM 7564 CG2 ILE D 249 17.875 -34.630 85.289 1.00201.27 C +ATOM 7565 CD1 ILE D 249 14.701 -34.913 85.638 1.00131.58 C +ATOM 7566 N LEU D 250 19.122 -33.424 88.459 1.00131.88 N +ATOM 7567 CA LEU D 250 20.267 -32.533 88.650 1.00137.00 C +ATOM 7568 C LEU D 250 21.370 -33.162 89.496 1.00161.56 C +ATOM 7569 O LEU D 250 22.556 -32.957 89.225 1.00183.91 O +ATOM 7570 CB LEU D 250 19.819 -31.218 89.286 1.00136.70 C +ATOM 7571 CG LEU D 250 19.194 -30.206 88.321 1.00140.20 C +ATOM 7572 CD1 LEU D 250 18.515 -29.061 89.055 1.00135.05 C +ATOM 7573 CD2 LEU D 250 20.254 -29.662 87.381 1.00157.52 C +ATOM 7574 N VAL D 251 20.981 -33.914 90.526 1.00177.74 N +ATOM 7575 CA VAL D 251 21.960 -34.593 91.383 1.00178.07 C +ATOM 7576 C VAL D 251 22.545 -35.835 90.703 1.00175.72 C +ATOM 7577 O VAL D 251 23.658 -36.261 91.024 1.00172.05 O +ATOM 7578 CB VAL D 251 21.371 -34.981 92.759 1.00164.40 C +ATOM 7579 CG1 VAL D 251 20.781 -33.757 93.449 1.00137.02 C +ATOM 7580 CG2 VAL D 251 20.340 -36.098 92.628 1.00174.87 C +ATOM 7581 N LYS D 252 21.791 -36.412 89.772 1.00161.69 N +ATOM 7582 CA LYS D 252 22.275 -37.545 88.990 1.00154.55 C +ATOM 7583 C LYS D 252 23.432 -37.109 88.075 1.00163.79 C +ATOM 7584 O LYS D 252 24.485 -37.752 88.026 1.00129.02 O +ATOM 7585 CB LYS D 252 21.110 -38.135 88.192 1.00145.14 C +ATOM 7586 CG LYS D 252 21.464 -39.311 87.297 1.00153.36 C +ATOM 7587 CD LYS D 252 20.227 -39.783 86.536 1.00165.38 C +ATOM 7588 CE LYS D 252 20.516 -39.985 85.053 1.00186.65 C +ATOM 7589 NZ LYS D 252 19.279 -40.187 84.249 1.00178.60 N +ATOM 7590 N TYR D 253 23.248 -35.981 87.391 1.00192.65 N +ATOM 7591 CA TYR D 253 24.265 -35.458 86.470 1.00186.08 C +ATOM 7592 C TYR D 253 25.398 -34.790 87.233 1.00176.23 C +ATOM 7593 O TYR D 253 26.545 -34.792 86.784 1.00153.16 O +ATOM 7594 CB TYR D 253 23.632 -34.495 85.447 1.00183.25 C +ATOM 7595 CG TYR D 253 22.781 -35.235 84.423 1.00174.67 C +ATOM 7596 CD1 TYR D 253 23.363 -35.838 83.311 1.00150.37 C +ATOM 7597 CD2 TYR D 253 21.405 -35.393 84.605 1.00184.32 C +ATOM 7598 CE1 TYR D 253 22.593 -36.545 82.400 1.00144.27 C +ATOM 7599 CE2 TYR D 253 20.627 -36.091 83.685 1.00160.74 C +ATOM 7600 CZ TYR D 253 21.232 -36.667 82.589 1.00147.99 C +ATOM 7601 OH TYR D 253 20.481 -37.372 81.683 1.00133.19 O +ATOM 7602 N ARG D 254 25.057 -34.197 88.376 1.00167.16 N +ATOM 7603 CA ARG D 254 26.063 -33.683 89.308 1.00143.99 C +ATOM 7604 C ARG D 254 26.987 -34.814 89.749 1.00142.79 C +ATOM 7605 O ARG D 254 28.205 -34.626 89.845 1.00170.00 O +ATOM 7606 CB ARG D 254 25.399 -33.056 90.538 1.00123.59 C +ATOM 7607 CG ARG D 254 26.386 -32.408 91.494 1.00121.82 C +ATOM 7608 CD ARG D 254 25.721 -31.454 92.474 1.00130.49 C +ATOM 7609 NE ARG D 254 25.133 -30.273 91.848 1.00136.02 N +ATOM 7610 CZ ARG D 254 23.827 -30.044 91.707 1.00161.77 C +ATOM 7611 NH1 ARG D 254 22.927 -30.914 92.142 1.00150.85 N +ATOM 7612 NH2 ARG D 254 23.417 -28.921 91.128 1.00185.76 N +ATOM 7613 N HIS D 255 26.397 -35.986 89.979 1.00147.41 N +ATOM 7614 CA HIS D 255 27.149 -37.167 90.397 1.00169.97 C +ATOM 7615 C HIS D 255 28.059 -37.706 89.295 1.00162.22 C +ATOM 7616 O HIS D 255 29.153 -38.210 89.577 1.00142.81 O +ATOM 7617 CB HIS D 255 26.204 -38.273 90.896 1.00193.39 C +ATOM 7618 CG HIS D 255 26.195 -38.439 92.389 1.00204.02 C +ATOM 7619 ND1 HIS D 255 25.558 -37.556 93.235 1.00200.25 N +ATOM 7620 CD2 HIS D 255 26.741 -39.391 93.183 1.00196.19 C +ATOM 7621 CE1 HIS D 255 25.714 -37.955 94.486 1.00179.03 C +ATOM 7622 NE2 HIS D 255 26.429 -39.066 94.482 1.00176.95 N +ATOM 7623 N MET D 256 27.626 -37.595 88.043 1.00143.42 N +ATOM 7624 CA MET D 256 28.451 -38.080 86.933 1.00162.35 C +ATOM 7625 C MET D 256 29.713 -37.217 86.728 1.00195.29 C +ATOM 7626 O MET D 256 30.728 -37.705 86.217 1.00191.15 O +ATOM 7627 CB MET D 256 27.624 -38.170 85.647 1.00147.81 C +ATOM 7628 CG MET D 256 26.341 -38.983 85.802 1.00150.03 C +ATOM 7629 SD MET D 256 25.593 -39.579 84.284 1.00130.49 S +ATOM 7630 CE MET D 256 26.820 -40.786 83.765 1.00 98.36 C +ATOM 7631 N SER D 257 29.662 -35.964 87.185 1.00207.19 N +ATOM 7632 CA SER D 257 30.820 -35.051 87.144 1.00179.73 C +ATOM 7633 C SER D 257 31.862 -35.384 88.211 1.00164.05 C +ATOM 7634 O SER D 257 32.792 -36.146 87.975 1.00119.85 O +ATOM 7635 CB SER D 257 30.360 -33.598 87.338 1.00162.15 C +ATOM 7636 OG SER D 257 29.213 -33.328 86.569 1.00169.13 O +TER 7637 SER D 257 +ATOM 7638 N LEU E 2 7.056 -54.243 66.401 1.00138.26 N +ATOM 7639 CA LEU E 2 8.545 -54.372 66.376 1.00146.44 C +ATOM 7640 C LEU E 2 9.057 -54.312 64.918 1.00153.62 C +ATOM 7641 O LEU E 2 9.559 -55.309 64.350 1.00112.22 O +ATOM 7642 CB LEU E 2 8.999 -55.655 67.094 1.00158.33 C +ATOM 7643 CG LEU E 2 8.675 -55.833 68.598 1.00141.65 C +ATOM 7644 CD1 LEU E 2 9.192 -57.190 69.078 1.00123.44 C +ATOM 7645 CD2 LEU E 2 9.208 -54.713 69.498 1.00123.05 C +ATOM 7646 N THR E 3 8.824 -53.143 64.314 1.00174.71 N +ATOM 7647 CA THR E 3 9.478 -52.686 63.081 1.00192.36 C +ATOM 7648 C THR E 3 9.780 -51.167 63.148 1.00207.91 C +ATOM 7649 O THR E 3 10.339 -50.575 62.209 1.00179.73 O +ATOM 7650 CB THR E 3 8.603 -52.941 61.836 1.00174.89 C +ATOM 7651 OG1 THR E 3 7.431 -52.099 61.887 1.00133.39 O +ATOM 7652 CG2 THR E 3 8.219 -54.416 61.732 1.00163.21 C +ATOM 7653 N ALA E 4 9.350 -50.527 64.231 1.00190.59 N +ATOM 7654 CA ALA E 4 9.889 -49.221 64.621 1.00143.34 C +ATOM 7655 C ALA E 4 11.310 -49.439 65.210 1.00129.75 C +ATOM 7656 O ALA E 4 11.831 -50.555 65.163 1.00 88.63 O +ATOM 7657 CB ALA E 4 8.938 -48.541 65.605 1.00115.63 C +ATOM 7658 N PRO E 5 11.967 -48.381 65.726 1.00125.76 N +ATOM 7659 CA PRO E 5 13.377 -48.643 65.963 1.00107.60 C +ATOM 7660 C PRO E 5 13.643 -49.408 67.254 1.00119.27 C +ATOM 7661 O PRO E 5 12.732 -49.605 68.062 1.00139.12 O +ATOM 7662 CB PRO E 5 13.965 -47.241 66.046 1.00124.85 C +ATOM 7663 CG PRO E 5 12.849 -46.353 66.523 1.00118.70 C +ATOM 7664 CD PRO E 5 11.552 -47.047 66.215 1.00128.91 C +ATOM 7665 N PRO E 6 14.879 -49.890 67.432 1.00157.26 N +ATOM 7666 CA PRO E 6 15.329 -50.417 68.733 1.00188.40 C +ATOM 7667 C PRO E 6 15.678 -49.307 69.716 1.00203.31 C +ATOM 7668 O PRO E 6 16.072 -48.218 69.294 1.00229.36 O +ATOM 7669 CB PRO E 6 16.571 -51.253 68.389 1.00182.49 C +ATOM 7670 CG PRO E 6 16.986 -50.837 67.025 1.00183.02 C +ATOM 7671 CD PRO E 6 15.847 -50.123 66.350 1.00167.00 C +ATOM 7672 N LYS E 7 15.546 -49.581 71.013 1.00185.80 N +ATOM 7673 CA LYS E 7 15.786 -48.551 72.028 1.00171.64 C +ATOM 7674 C LYS E 7 17.206 -48.610 72.591 1.00154.77 C +ATOM 7675 O LYS E 7 17.954 -49.569 72.328 1.00109.74 O +ATOM 7676 CB LYS E 7 14.767 -48.638 73.165 1.00158.80 C +ATOM 7677 CG LYS E 7 13.356 -48.273 72.769 1.00151.43 C +ATOM 7678 CD LYS E 7 12.444 -49.487 72.625 1.00136.76 C +ATOM 7679 CE LYS E 7 10.991 -49.047 72.544 1.00168.49 C +ATOM 7680 NZ LYS E 7 10.159 -49.994 71.753 1.00186.23 N +ATOM 7681 N GLU E 8 17.567 -47.559 73.336 1.00148.14 N +ATOM 7682 CA GLU E 8 18.967 -47.273 73.682 1.00136.94 C +ATOM 7683 C GLU E 8 19.572 -48.322 74.592 1.00121.28 C +ATOM 7684 O GLU E 8 19.099 -48.546 75.696 1.00172.05 O +ATOM 7685 CB GLU E 8 19.136 -45.852 74.307 1.00133.40 C +ATOM 7686 CG GLU E 8 18.804 -45.668 75.772 1.00128.92 C +ATOM 7687 CD GLU E 8 19.224 -44.296 76.307 1.00138.30 C +ATOM 7688 OE1 GLU E 8 20.414 -43.924 76.183 1.00128.45 O +ATOM 7689 OE2 GLU E 8 18.379 -43.596 76.898 1.00118.40 O +ATOM 7690 N ALA E 9 20.607 -48.985 74.098 1.00110.65 N +ATOM 7691 CA ALA E 9 21.407 -49.902 74.896 1.00118.36 C +ATOM 7692 C ALA E 9 22.636 -49.174 75.442 1.00137.01 C +ATOM 7693 O ALA E 9 23.512 -48.770 74.674 1.00197.32 O +ATOM 7694 CB ALA E 9 21.827 -51.085 74.039 1.00109.14 C +ATOM 7695 N ALA E 10 22.688 -49.021 76.764 1.00118.01 N +ATOM 7696 CA ALA E 10 23.680 -48.187 77.466 1.00116.88 C +ATOM 7697 C ALA E 10 23.240 -46.721 77.487 1.00116.70 C +ATOM 7698 O ALA E 10 22.433 -46.299 76.676 1.00 95.50 O +ATOM 7699 CB ALA E 10 25.094 -48.332 76.886 1.00 94.90 C +ATOM 7700 N ARG E 11 23.744 -45.945 78.439 1.00136.59 N +ATOM 7701 CA ARG E 11 23.316 -44.552 78.561 1.00148.60 C +ATOM 7702 C ARG E 11 24.470 -43.664 78.117 1.00158.93 C +ATOM 7703 O ARG E 11 25.631 -44.061 78.214 1.00171.19 O +ATOM 7704 CB ARG E 11 22.741 -44.289 79.954 1.00153.98 C +ATOM 7705 CG ARG E 11 21.438 -45.019 80.236 1.00163.92 C +ATOM 7706 CD ARG E 11 20.899 -44.675 81.615 1.00157.32 C +ATOM 7707 NE ARG E 11 19.684 -45.422 81.929 1.00158.42 N +ATOM 7708 CZ ARG E 11 19.076 -45.395 83.110 1.00144.07 C +ATOM 7709 NH1 ARG E 11 19.568 -44.657 84.096 1.00123.28 N +ATOM 7710 NH2 ARG E 11 17.974 -46.106 83.307 1.00138.87 N +ATOM 7711 N PRO E 12 24.163 -42.462 77.633 1.00166.70 N +ATOM 7712 CA PRO E 12 25.223 -41.502 77.356 1.00157.96 C +ATOM 7713 C PRO E 12 25.940 -41.135 78.645 1.00139.57 C +ATOM 7714 O PRO E 12 25.339 -40.575 79.561 1.00124.72 O +ATOM 7715 CB PRO E 12 24.476 -40.290 76.783 1.00186.43 C +ATOM 7716 CG PRO E 12 23.097 -40.770 76.460 1.00192.94 C +ATOM 7717 CD PRO E 12 22.827 -41.889 77.414 1.00167.88 C +ATOM 7718 N THR E 13 27.207 -41.509 78.734 1.00131.53 N +ATOM 7719 CA THR E 13 28.081 -41.026 79.796 1.00121.64 C +ATOM 7720 C THR E 13 28.844 -39.788 79.326 1.00135.58 C +ATOM 7721 O THR E 13 28.982 -39.582 78.116 1.00174.93 O +ATOM 7722 CB THR E 13 29.080 -42.122 80.194 1.00101.71 C +ATOM 7723 OG1 THR E 13 29.780 -41.718 81.376 1.00121.33 O +ATOM 7724 CG2 THR E 13 30.079 -42.441 79.041 1.00 81.28 C +ATOM 7725 N LEU E 14 29.382 -38.993 80.249 1.00114.26 N +ATOM 7726 CA LEU E 14 30.358 -37.995 79.816 1.00110.34 C +ATOM 7727 C LEU E 14 31.715 -38.686 79.510 1.00 75.50 C +ATOM 7728 O LEU E 14 31.897 -39.824 79.829 1.00 52.74 O +ATOM 7729 CB LEU E 14 30.489 -36.820 80.785 1.00106.38 C +ATOM 7730 CG LEU E 14 30.817 -37.120 82.225 1.00108.35 C +ATOM 7731 CD1 LEU E 14 31.681 -36.015 82.814 1.00104.57 C +ATOM 7732 CD2 LEU E 14 29.527 -37.238 82.985 1.00113.99 C +ATOM 7733 N MET E 15 32.540 -38.077 78.676 1.00 84.04 N +ATOM 7734 CA MET E 15 33.460 -38.843 77.827 1.00 96.35 C +ATOM 7735 C MET E 15 34.514 -39.465 78.729 1.00 91.51 C +ATOM 7736 O MET E 15 35.253 -38.740 79.407 1.00105.11 O +ATOM 7737 CB MET E 15 34.091 -37.963 76.698 1.00125.94 C +ATOM 7738 CG MET E 15 34.509 -38.747 75.445 1.00107.57 C +ATOM 7739 SD MET E 15 35.957 -38.225 74.475 1.00115.69 S +ATOM 7740 CE MET E 15 36.985 -37.265 75.585 1.00 85.75 C +ATOM 7741 N PRO E 16 34.655 -40.797 78.654 1.00 98.57 N +ATOM 7742 CA PRO E 16 35.588 -41.578 79.465 1.00112.66 C +ATOM 7743 C PRO E 16 37.088 -41.233 79.347 1.00108.20 C +ATOM 7744 O PRO E 16 37.862 -41.943 78.686 1.00 78.90 O +ATOM 7745 CB PRO E 16 35.328 -43.022 79.003 1.00115.44 C +ATOM 7746 CG PRO E 16 34.839 -42.887 77.616 1.00115.99 C +ATOM 7747 CD PRO E 16 34.027 -41.626 77.608 1.00100.99 C +ATOM 7748 N ARG E 17 37.491 -40.173 80.037 1.00101.47 N +ATOM 7749 CA ARG E 17 38.898 -39.834 80.165 1.00124.53 C +ATOM 7750 C ARG E 17 39.487 -40.571 81.372 1.00110.31 C +ATOM 7751 O ARG E 17 38.801 -40.767 82.354 1.00142.59 O +ATOM 7752 CB ARG E 17 39.050 -38.315 80.319 1.00128.05 C +ATOM 7753 CG ARG E 17 39.123 -37.568 78.990 1.00132.53 C +ATOM 7754 CD ARG E 17 38.856 -36.077 79.125 1.00137.30 C +ATOM 7755 NE ARG E 17 37.438 -35.787 79.269 1.00144.07 N +ATOM 7756 CZ ARG E 17 36.949 -34.586 79.571 1.00147.32 C +ATOM 7757 NH1 ARG E 17 37.769 -33.552 79.699 1.00121.92 N +ATOM 7758 NH2 ARG E 17 35.634 -34.418 79.694 1.00143.27 N +ATOM 7759 N ALA E 18 40.754 -40.967 81.302 1.00107.64 N +ATOM 7760 CA ALA E 18 41.373 -41.742 82.388 1.00106.50 C +ATOM 7761 C ALA E 18 42.484 -40.994 83.140 1.00104.25 C +ATOM 7762 O ALA E 18 42.231 -39.940 83.727 1.00 59.45 O +ATOM 7763 CB ALA E 18 41.881 -43.078 81.862 1.00122.67 C +ATOM 7764 N GLN E 19 43.718 -41.504 83.068 1.00118.90 N +ATOM 7765 CA GLN E 19 44.756 -41.110 84.025 1.00141.28 C +ATOM 7766 C GLN E 19 45.255 -39.679 83.810 1.00117.62 C +ATOM 7767 O GLN E 19 45.316 -38.872 84.748 1.00 77.38 O +ATOM 7768 CB GLN E 19 45.940 -42.081 83.949 1.00159.34 C +ATOM 7769 CG GLN E 19 46.998 -41.862 85.023 1.00168.53 C +ATOM 7770 CD GLN E 19 46.426 -41.883 86.434 1.00210.24 C +ATOM 7771 OE1 GLN E 19 45.940 -42.918 86.904 1.00275.98 O +ATOM 7772 NE2 GLN E 19 46.451 -40.734 87.106 1.00205.95 N +ATOM 7773 N SER E 20 45.616 -39.395 82.560 1.00116.35 N +ATOM 7774 CA SER E 20 45.982 -38.056 82.119 1.00107.33 C +ATOM 7775 C SER E 20 45.028 -37.008 82.691 1.00108.99 C +ATOM 7776 O SER E 20 45.464 -36.023 83.287 1.00134.91 O +ATOM 7777 CB SER E 20 45.974 -38.001 80.582 1.00105.80 C +ATOM 7778 OG SER E 20 46.741 -39.066 80.041 1.00131.59 O +ATOM 7779 N TYR E 21 43.726 -37.237 82.516 1.00112.10 N +ATOM 7780 CA TYR E 21 42.677 -36.367 83.071 1.00107.61 C +ATOM 7781 C TYR E 21 42.777 -36.170 84.595 1.00120.15 C +ATOM 7782 O TYR E 21 42.764 -35.033 85.089 1.00106.64 O +ATOM 7783 CB TYR E 21 41.294 -36.935 82.750 1.00101.06 C +ATOM 7784 CG TYR E 21 40.147 -36.073 83.226 1.00103.32 C +ATOM 7785 CD1 TYR E 21 39.799 -34.919 82.524 1.00174.19 C +ATOM 7786 CD2 TYR E 21 39.419 -36.391 84.362 1.00 70.59 C +ATOM 7787 CE1 TYR E 21 38.762 -34.111 82.946 1.00167.94 C +ATOM 7788 CE2 TYR E 21 38.371 -35.601 84.778 1.00 74.13 C +ATOM 7789 CZ TYR E 21 38.050 -34.453 84.068 1.00122.01 C +ATOM 7790 OH TYR E 21 37.072 -33.576 84.481 1.00116.73 O +ATOM 7791 N LYS E 22 42.897 -37.274 85.325 1.00135.22 N +ATOM 7792 CA LYS E 22 42.979 -37.226 86.778 1.00142.84 C +ATOM 7793 C LYS E 22 44.181 -36.417 87.271 1.00132.48 C +ATOM 7794 O LYS E 22 44.075 -35.664 88.243 1.00 97.86 O +ATOM 7795 CB LYS E 22 43.053 -38.645 87.343 1.00161.87 C +ATOM 7796 CG LYS E 22 41.695 -39.265 87.598 1.00146.44 C +ATOM 7797 CD LYS E 22 41.136 -38.782 88.944 1.00142.99 C +ATOM 7798 CE LYS E 22 41.314 -39.873 90.009 1.00169.75 C +ATOM 7799 NZ LYS E 22 40.501 -41.080 89.699 1.00179.89 N +ATOM 7800 N ASP E 23 45.323 -36.605 86.616 1.00114.70 N +ATOM 7801 CA ASP E 23 46.499 -35.792 86.883 1.00120.55 C +ATOM 7802 C ASP E 23 46.244 -34.317 86.572 1.00127.25 C +ATOM 7803 O ASP E 23 46.607 -33.430 87.350 1.00125.81 O +ATOM 7804 CB ASP E 23 47.686 -36.290 86.048 1.00126.51 C +ATOM 7805 CG ASP E 23 48.135 -37.656 86.465 1.00139.98 C +ATOM 7806 OD1 ASP E 23 48.205 -37.889 87.689 1.00158.67 O +ATOM 7807 OD2 ASP E 23 48.479 -38.468 85.583 1.00155.34 O +ATOM 7808 N LEU E 24 45.652 -34.069 85.407 1.00123.53 N +ATOM 7809 CA LEU E 24 45.452 -32.717 84.885 1.00123.88 C +ATOM 7810 C LEU E 24 44.511 -31.891 85.770 1.00143.01 C +ATOM 7811 O LEU E 24 44.707 -30.675 85.934 1.00170.62 O +ATOM 7812 CB LEU E 24 44.883 -32.794 83.465 1.00133.79 C +ATOM 7813 CG LEU E 24 44.596 -31.484 82.728 1.00140.81 C +ATOM 7814 CD1 LEU E 24 45.846 -30.973 82.018 1.00152.39 C +ATOM 7815 CD2 LEU E 24 43.455 -31.675 81.733 1.00135.13 C +ATOM 7816 N THR E 25 43.509 -32.557 86.352 1.00150.53 N +ATOM 7817 CA THR E 25 42.510 -31.883 87.197 1.00146.14 C +ATOM 7818 C THR E 25 43.055 -31.539 88.586 1.00155.03 C +ATOM 7819 O THR E 25 42.917 -30.403 89.050 1.00135.28 O +ATOM 7820 CB THR E 25 41.244 -32.738 87.363 1.00131.13 C +ATOM 7821 OG1 THR E 25 41.611 -34.091 87.664 1.00132.22 O +ATOM 7822 CG2 THR E 25 40.435 -32.719 86.088 1.00149.28 C +ATOM 7823 N HIS E 26 43.734 -32.504 89.205 1.00159.07 N +ATOM 7824 CA HIS E 26 44.278 -32.340 90.551 1.00139.69 C +ATOM 7825 C HIS E 26 45.657 -31.669 90.528 1.00125.85 C +ATOM 7826 O HIS E 26 46.543 -31.998 91.313 1.00158.47 O +ATOM 7827 CB HIS E 26 44.332 -33.709 91.255 1.00173.00 C +ATOM 7828 CG HIS E 26 42.975 -34.328 91.475 1.00183.01 C +ATOM 7829 ND1 HIS E 26 42.201 -34.819 90.442 1.00185.81 N +ATOM 7830 CD2 HIS E 26 42.251 -34.523 92.606 1.00156.94 C +ATOM 7831 CE1 HIS E 26 41.070 -35.301 90.928 1.00146.99 C +ATOM 7832 NE2 HIS E 26 41.071 -35.126 92.237 1.00132.29 N +ATOM 7833 N LEU E 27 45.847 -30.720 89.625 1.00129.89 N +ATOM 7834 CA LEU E 27 47.083 -29.942 89.594 1.00133.99 C +ATOM 7835 C LEU E 27 46.939 -28.725 90.508 1.00137.35 C +ATOM 7836 O LEU E 27 45.922 -28.041 90.468 1.00126.89 O +ATOM 7837 CB LEU E 27 47.413 -29.488 88.165 1.00127.63 C +ATOM 7838 CG LEU E 27 48.235 -30.471 87.329 1.00128.73 C +ATOM 7839 CD1 LEU E 27 48.226 -30.079 85.858 1.00144.15 C +ATOM 7840 CD2 LEU E 27 49.664 -30.562 87.839 1.00133.72 C +ATOM 7841 N PRO E 28 47.979 -28.431 91.306 1.00135.12 N +ATOM 7842 CA PRO E 28 47.963 -27.286 92.224 1.00131.86 C +ATOM 7843 C PRO E 28 47.792 -25.968 91.497 1.00150.49 C +ATOM 7844 O PRO E 28 48.492 -25.723 90.522 1.00205.20 O +ATOM 7845 CB PRO E 28 49.346 -27.333 92.861 1.00144.13 C +ATOM 7846 CG PRO E 28 50.205 -28.082 91.887 1.00131.51 C +ATOM 7847 CD PRO E 28 49.296 -29.095 91.270 1.00135.93 C +ATOM 7848 N ALA E 29 46.844 -25.146 91.937 1.00152.46 N +ATOM 7849 CA ALA E 29 46.392 -23.998 91.139 1.00160.95 C +ATOM 7850 C ALA E 29 47.417 -22.845 91.145 1.00161.07 C +ATOM 7851 O ALA E 29 48.182 -22.690 92.097 1.00142.63 O +ATOM 7852 CB ALA E 29 45.031 -23.511 91.625 1.00151.48 C +ATOM 7853 N PRO E 30 47.506 -22.098 90.027 1.00162.15 N +ATOM 7854 CA PRO E 30 48.406 -20.941 89.908 1.00131.99 C +ATOM 7855 C PRO E 30 47.858 -19.731 90.656 1.00112.53 C +ATOM 7856 O PRO E 30 46.715 -19.779 91.144 1.00 84.60 O +ATOM 7857 CB PRO E 30 48.400 -20.662 88.410 1.00153.34 C +ATOM 7858 CG PRO E 30 47.057 -21.135 87.938 1.00147.44 C +ATOM 7859 CD PRO E 30 46.680 -22.290 88.815 1.00157.41 C +ATOM 7860 N THR E 31 48.622 -18.635 90.679 1.00102.30 N +ATOM 7861 CA THR E 31 48.186 -17.400 91.372 1.00129.46 C +ATOM 7862 C THR E 31 46.988 -16.707 90.701 1.00129.66 C +ATOM 7863 O THR E 31 46.198 -16.033 91.359 1.00126.04 O +ATOM 7864 CB THR E 31 49.322 -16.360 91.525 1.00126.82 C +ATOM 7865 OG1 THR E 31 49.915 -16.079 90.253 1.00144.34 O +ATOM 7866 CG2 THR E 31 50.387 -16.859 92.483 1.00131.56 C +ATOM 7867 N GLY E 32 46.852 -16.899 89.396 1.00138.74 N +ATOM 7868 CA GLY E 32 45.627 -16.551 88.679 1.00135.57 C +ATOM 7869 C GLY E 32 45.551 -17.384 87.414 1.00133.46 C +ATOM 7870 O GLY E 32 46.582 -17.873 86.939 1.00163.00 O +ATOM 7871 N LYS E 33 44.347 -17.604 86.892 1.00100.92 N +ATOM 7872 CA LYS E 33 44.233 -18.344 85.647 1.00110.30 C +ATOM 7873 C LYS E 33 44.828 -17.528 84.494 1.00125.29 C +ATOM 7874 O LYS E 33 44.818 -16.296 84.534 1.00114.81 O +ATOM 7875 CB LYS E 33 42.786 -18.724 85.354 1.00104.28 C +ATOM 7876 CG LYS E 33 42.375 -20.069 85.913 1.00118.12 C +ATOM 7877 CD LYS E 33 40.883 -20.291 85.740 1.00114.18 C +ATOM 7878 CE LYS E 33 40.363 -21.249 86.786 1.00124.84 C +ATOM 7879 NZ LYS E 33 38.887 -21.352 86.737 1.00140.97 N +ATOM 7880 N ILE E 34 45.355 -18.214 83.479 1.00138.82 N +ATOM 7881 CA ILE E 34 45.995 -17.544 82.352 1.00131.37 C +ATOM 7882 C ILE E 34 45.045 -17.608 81.138 1.00140.85 C +ATOM 7883 O ILE E 34 44.279 -18.571 80.980 1.00132.74 O +ATOM 7884 CB ILE E 34 47.408 -18.139 82.078 1.00113.23 C +ATOM 7885 CG1 ILE E 34 48.336 -17.841 83.248 1.00 98.50 C +ATOM 7886 CG2 ILE E 34 48.039 -17.555 80.824 1.00129.34 C +ATOM 7887 CD1 ILE E 34 48.840 -19.077 83.936 1.00107.88 C +ATOM 7888 N PHE E 35 45.012 -16.516 80.373 1.00117.86 N +ATOM 7889 CA PHE E 35 44.163 -16.389 79.201 1.00 97.07 C +ATOM 7890 C PHE E 35 44.837 -17.032 78.005 1.00103.46 C +ATOM 7891 O PHE E 35 45.939 -16.637 77.653 1.00118.57 O +ATOM 7892 CB PHE E 35 43.957 -14.917 78.907 1.00 77.19 C +ATOM 7893 CG PHE E 35 42.840 -14.294 79.683 1.00 79.63 C +ATOM 7894 CD1 PHE E 35 41.590 -14.912 79.771 1.00 84.14 C +ATOM 7895 CD2 PHE E 35 42.984 -13.015 80.199 1.00 90.08 C +ATOM 7896 CE1 PHE E 35 40.535 -14.298 80.429 1.00 91.73 C +ATOM 7897 CE2 PHE E 35 41.913 -12.370 80.810 1.00 95.01 C +ATOM 7898 CZ PHE E 35 40.692 -13.015 80.933 1.00100.18 C +ATOM 7899 N VAL E 36 44.162 -17.977 77.347 1.00115.41 N +ATOM 7900 CA VAL E 36 44.788 -18.705 76.214 1.00111.44 C +ATOM 7901 C VAL E 36 43.879 -18.719 74.966 1.00 89.54 C +ATOM 7902 O VAL E 36 42.661 -18.719 75.069 1.00 88.59 O +ATOM 7903 CB VAL E 36 45.181 -20.188 76.548 1.00 98.89 C +ATOM 7904 CG1 VAL E 36 46.147 -20.296 77.731 1.00 85.78 C +ATOM 7905 CG2 VAL E 36 43.910 -21.002 76.800 1.00102.06 C +ATOM 7906 N SER E 37 44.508 -18.796 73.806 1.00 64.20 N +ATOM 7907 CA SER E 37 43.797 -18.884 72.558 1.00 48.29 C +ATOM 7908 C SER E 37 44.227 -20.074 71.782 1.00 46.21 C +ATOM 7909 O SER E 37 45.422 -20.389 71.689 1.00 53.59 O +ATOM 7910 CB SER E 37 44.159 -17.702 71.718 1.00 58.30 C +ATOM 7911 OG SER E 37 43.557 -16.511 72.182 1.00 94.41 O +ATOM 7912 N VAL E 38 43.280 -20.831 71.288 1.00 66.34 N +ATOM 7913 CA VAL E 38 43.644 -21.928 70.374 1.00114.48 C +ATOM 7914 C VAL E 38 42.891 -21.719 69.069 1.00131.41 C +ATOM 7915 O VAL E 38 41.648 -21.748 69.059 1.00168.35 O +ATOM 7916 CB VAL E 38 43.280 -23.350 70.905 1.00138.01 C +ATOM 7917 CG1 VAL E 38 43.616 -24.402 69.859 1.00146.06 C +ATOM 7918 CG2 VAL E 38 43.984 -23.685 72.214 1.00102.78 C +ATOM 7919 N TYR E 39 43.642 -21.556 67.979 1.00106.94 N +ATOM 7920 CA TYR E 39 43.058 -21.281 66.671 1.00 84.71 C +ATOM 7921 C TYR E 39 42.825 -22.623 65.964 1.00 75.22 C +ATOM 7922 O TYR E 39 41.723 -22.900 65.488 1.00 78.49 O +ATOM 7923 CB TYR E 39 43.957 -20.302 65.856 1.00 84.72 C +ATOM 7924 CG TYR E 39 43.716 -18.798 66.151 1.00 78.05 C +ATOM 7925 CD1 TYR E 39 44.178 -18.204 67.337 1.00 88.31 C +ATOM 7926 CD2 TYR E 39 43.006 -17.995 65.277 1.00 87.36 C +ATOM 7927 CE1 TYR E 39 43.935 -16.854 67.636 1.00 59.46 C +ATOM 7928 CE2 TYR E 39 42.712 -16.660 65.594 1.00 79.47 C +ATOM 7929 CZ TYR E 39 43.192 -16.091 66.771 1.00 59.18 C +ATOM 7930 OH TYR E 39 42.943 -14.783 67.040 1.00 33.10 O +ATOM 7931 N ASN E 40 43.858 -23.456 65.883 1.00 72.76 N +ATOM 7932 CA ASN E 40 43.743 -24.730 65.149 1.00 83.43 C +ATOM 7933 C ASN E 40 44.917 -25.711 65.358 1.00 92.88 C +ATOM 7934 O ASN E 40 46.087 -25.326 65.268 1.00 94.59 O +ATOM 7935 CB ASN E 40 43.609 -24.470 63.647 1.00 91.84 C +ATOM 7936 CG ASN E 40 43.035 -25.650 62.906 1.00 91.93 C +ATOM 7937 OD1 ASN E 40 43.708 -26.265 62.068 1.00109.47 O +ATOM 7938 ND2 ASN E 40 41.810 -26.014 63.253 1.00 92.46 N +ATOM 7939 N ILE E 41 44.586 -26.971 65.637 1.00 72.68 N +ATOM 7940 CA ILE E 41 45.570 -28.038 65.655 1.00 72.65 C +ATOM 7941 C ILE E 41 45.208 -29.060 64.572 1.00 72.60 C +ATOM 7942 O ILE E 41 44.158 -29.694 64.630 1.00 52.71 O +ATOM 7943 CB ILE E 41 45.640 -28.735 67.033 1.00 89.59 C +ATOM 7944 CG1 ILE E 41 46.478 -27.925 68.040 1.00 89.08 C +ATOM 7945 CG2 ILE E 41 46.317 -30.093 66.902 1.00105.70 C +ATOM 7946 CD1 ILE E 41 45.858 -26.631 68.540 1.00 68.37 C +ATOM 7947 N GLN E 42 46.086 -29.228 63.590 1.00 78.15 N +ATOM 7948 CA GLN E 42 45.733 -29.973 62.362 1.00 81.58 C +ATOM 7949 C GLN E 42 46.057 -31.430 62.471 1.00 77.55 C +ATOM 7950 O GLN E 42 46.950 -31.830 63.254 1.00108.16 O +ATOM 7951 CB GLN E 42 46.482 -29.417 61.145 1.00116.96 C +ATOM 7952 CG GLN E 42 46.086 -28.002 60.764 1.00141.67 C +ATOM 7953 CD GLN E 42 47.255 -27.023 60.846 1.00160.16 C +ATOM 7954 OE1 GLN E 42 48.012 -26.863 59.879 1.00155.45 O +ATOM 7955 NE2 GLN E 42 47.431 -26.385 62.015 1.00128.34 N +ATOM 7956 N ASP E 43 45.386 -32.225 61.647 1.00 67.32 N +ATOM 7957 CA ASP E 43 45.747 -33.647 61.453 1.00 80.79 C +ATOM 7958 C ASP E 43 46.933 -33.791 60.486 1.00 67.74 C +ATOM 7959 O ASP E 43 46.763 -34.313 59.383 1.00 43.19 O +ATOM 7960 CB ASP E 43 44.521 -34.426 60.924 1.00 73.97 C +ATOM 7961 CG ASP E 43 44.724 -35.950 60.918 1.00101.66 C +ATOM 7962 OD1 ASP E 43 45.200 -36.489 61.953 1.00183.06 O +ATOM 7963 OD2 ASP E 43 44.500 -36.611 59.879 1.00 63.23 O +ATOM 7964 N GLU E 44 48.096 -33.279 60.889 1.00 60.84 N +ATOM 7965 CA GLU E 44 49.253 -33.249 60.014 1.00 70.10 C +ATOM 7966 C GLU E 44 49.775 -34.683 59.706 1.00 77.46 C +ATOM 7967 O GLU E 44 50.951 -34.850 59.277 1.00 61.12 O +ATOM 7968 CB GLU E 44 50.362 -32.341 60.609 1.00 91.56 C +ATOM 7969 CG GLU E 44 50.279 -30.863 60.210 1.00115.13 C +ATOM 7970 CD GLU E 44 51.369 -29.954 60.859 1.00133.70 C +ATOM 7971 OE1 GLU E 44 52.577 -30.309 60.875 1.00118.42 O +ATOM 7972 OE2 GLU E 44 51.025 -28.817 61.286 1.00 89.65 O +ATOM 7973 N THR E 45 48.953 -35.711 59.993 1.00 60.22 N +ATOM 7974 CA THR E 45 49.445 -37.119 60.085 1.00 56.80 C +ATOM 7975 C THR E 45 49.597 -37.783 58.747 1.00 48.02 C +ATOM 7976 O THR E 45 50.591 -38.451 58.489 1.00 27.82 O +ATOM 7977 CB THR E 45 48.568 -37.996 60.997 1.00 55.29 C +ATOM 7978 OG1 THR E 45 49.233 -39.242 61.247 1.00 61.28 O +ATOM 7979 CG2 THR E 45 47.242 -38.270 60.375 1.00 57.09 C +ATOM 7980 N GLY E 46 48.689 -37.453 57.844 1.00 58.89 N +ATOM 7981 CA GLY E 46 48.832 -37.859 56.424 1.00 91.89 C +ATOM 7982 C GLY E 46 48.274 -39.263 56.148 1.00118.09 C +ATOM 7983 O GLY E 46 48.550 -39.920 55.145 1.00 69.81 O +ATOM 7984 N GLN E 47 47.375 -39.691 56.996 1.00150.80 N +ATOM 7985 CA GLN E 47 47.121 -41.073 57.030 1.00140.06 C +ATOM 7986 C GLN E 47 45.637 -41.366 57.064 1.00127.55 C +ATOM 7987 O GLN E 47 44.846 -40.690 57.746 1.00129.46 O +ATOM 7988 CB GLN E 47 47.837 -41.646 58.224 1.00147.14 C +ATOM 7989 CG GLN E 47 49.361 -41.623 58.101 1.00104.23 C +ATOM 7990 CD GLN E 47 49.858 -42.205 56.807 1.00 88.07 C +ATOM 7991 OE1 GLN E 47 49.767 -43.407 56.585 1.00 66.73 O +ATOM 7992 NE2 GLN E 47 50.332 -41.367 55.934 1.00 91.87 N +ATOM 7993 N PHE E 48 45.282 -42.388 56.306 1.00121.38 N +ATOM 7994 CA PHE E 48 43.910 -42.841 56.207 1.00128.61 C +ATOM 7995 C PHE E 48 43.834 -44.317 56.546 1.00136.03 C +ATOM 7996 O PHE E 48 44.844 -45.039 56.552 1.00139.77 O +ATOM 7997 CB PHE E 48 43.363 -42.604 54.785 1.00131.71 C +ATOM 7998 CG PHE E 48 43.236 -41.174 54.439 1.00124.32 C +ATOM 7999 CD1 PHE E 48 44.364 -40.428 54.150 1.00123.11 C +ATOM 8000 CD2 PHE E 48 42.017 -40.552 54.507 1.00123.40 C +ATOM 8001 CE1 PHE E 48 44.282 -39.074 53.943 1.00100.56 C +ATOM 8002 CE2 PHE E 48 41.926 -39.202 54.270 1.00128.33 C +ATOM 8003 CZ PHE E 48 43.058 -38.465 53.977 1.00101.62 C +ATOM 8004 N LYS E 49 42.601 -44.788 56.708 1.00119.58 N +ATOM 8005 CA LYS E 49 42.358 -46.177 57.081 1.00 79.81 C +ATOM 8006 C LYS E 49 42.483 -47.030 55.847 1.00 74.63 C +ATOM 8007 O LYS E 49 42.126 -46.604 54.745 1.00 83.45 O +ATOM 8008 CB LYS E 49 40.990 -46.343 57.765 1.00 67.34 C +ATOM 8009 CG LYS E 49 40.916 -45.618 59.109 1.00 68.43 C +ATOM 8010 CD LYS E 49 39.685 -45.852 59.971 1.00 60.21 C +ATOM 8011 CE LYS E 49 39.933 -45.143 61.313 1.00 63.92 C +ATOM 8012 NZ LYS E 49 38.875 -45.311 62.342 1.00 68.69 N +ATOM 8013 N PRO E 50 42.999 -48.246 56.024 1.00 94.85 N +ATOM 8014 CA PRO E 50 43.117 -49.190 54.923 1.00113.75 C +ATOM 8015 C PRO E 50 41.773 -49.849 54.545 1.00122.60 C +ATOM 8016 O PRO E 50 40.804 -49.807 55.331 1.00111.80 O +ATOM 8017 CB PRO E 50 44.125 -50.217 55.467 1.00116.43 C +ATOM 8018 CG PRO E 50 43.931 -50.186 56.949 1.00106.78 C +ATOM 8019 CD PRO E 50 43.534 -48.783 57.293 1.00100.86 C +ATOM 8020 N TYR E 51 41.749 -50.513 53.394 1.00116.58 N +ATOM 8021 CA TYR E 51 40.647 -51.393 53.085 1.00127.41 C +ATOM 8022 C TYR E 51 40.334 -52.323 54.268 1.00152.08 C +ATOM 8023 O TYR E 51 41.248 -52.907 54.855 1.00188.99 O +ATOM 8024 CB TYR E 51 40.937 -52.234 51.841 1.00138.33 C +ATOM 8025 CG TYR E 51 39.655 -52.833 51.283 1.00161.48 C +ATOM 8026 CD1 TYR E 51 38.833 -52.082 50.446 1.00147.72 C +ATOM 8027 CD2 TYR E 51 39.236 -54.121 51.626 1.00184.80 C +ATOM 8028 CE1 TYR E 51 37.649 -52.583 49.927 1.00127.28 C +ATOM 8029 CE2 TYR E 51 38.047 -54.643 51.088 1.00174.10 C +ATOM 8030 CZ TYR E 51 37.247 -53.841 50.268 1.00148.16 C +ATOM 8031 OH TYR E 51 36.068 -54.286 49.722 1.00170.46 O +ATOM 8032 N PRO E 52 39.041 -52.493 54.614 1.00149.98 N +ATOM 8033 CA PRO E 52 37.828 -52.034 53.926 1.00132.34 C +ATOM 8034 C PRO E 52 37.251 -50.683 54.316 1.00118.75 C +ATOM 8035 O PRO E 52 36.073 -50.439 54.029 1.00105.75 O +ATOM 8036 CB PRO E 52 36.824 -53.137 54.270 1.00137.63 C +ATOM 8037 CG PRO E 52 37.216 -53.554 55.653 1.00131.69 C +ATOM 8038 CD PRO E 52 38.719 -53.432 55.713 1.00130.96 C +ATOM 8039 N ALA E 53 38.031 -49.828 54.977 1.00101.70 N +ATOM 8040 CA ALA E 53 37.524 -48.502 55.338 1.00 92.27 C +ATOM 8041 C ALA E 53 37.291 -47.682 54.100 1.00 84.88 C +ATOM 8042 O ALA E 53 37.775 -48.014 52.990 1.00 70.13 O +ATOM 8043 CB ALA E 53 38.479 -47.761 56.228 1.00 89.98 C +ATOM 8044 N SER E 54 36.490 -46.637 54.252 1.00 71.84 N +ATOM 8045 CA SER E 54 36.343 -45.745 53.128 1.00101.42 C +ATOM 8046 C SER E 54 37.725 -45.183 52.840 1.00112.85 C +ATOM 8047 O SER E 54 38.498 -44.884 53.750 1.00102.94 O +ATOM 8048 CB SER E 54 35.333 -44.626 53.411 1.00131.66 C +ATOM 8049 OG SER E 54 35.554 -43.464 52.611 1.00116.58 O +ATOM 8050 N ASN E 55 38.004 -44.983 51.555 1.00132.74 N +ATOM 8051 CA ASN E 55 39.223 -44.324 51.122 1.00110.56 C +ATOM 8052 C ASN E 55 39.481 -42.992 51.856 1.00105.96 C +ATOM 8053 O ASN E 55 40.634 -42.603 52.090 1.00112.66 O +ATOM 8054 CB ASN E 55 39.139 -44.063 49.634 1.00 88.19 C +ATOM 8055 CG ASN E 55 40.486 -43.844 49.028 1.00122.90 C +ATOM 8056 OD1 ASN E 55 41.532 -44.193 49.583 1.00123.47 O +ATOM 8057 ND2 ASN E 55 40.470 -43.234 47.892 1.00165.75 N +ATOM 8058 N PHE E 56 38.388 -42.348 52.275 1.00116.74 N +ATOM 8059 CA PHE E 56 38.425 -41.011 52.848 1.00 82.53 C +ATOM 8060 C PHE E 56 38.439 -41.020 54.356 1.00 88.55 C +ATOM 8061 O PHE E 56 38.397 -39.961 54.970 1.00123.14 O +ATOM 8062 CB PHE E 56 37.174 -40.221 52.449 1.00 98.84 C +ATOM 8063 CG PHE E 56 36.968 -40.084 50.969 1.00111.45 C +ATOM 8064 CD1 PHE E 56 37.891 -39.401 50.172 1.00124.15 C +ATOM 8065 CD2 PHE E 56 35.839 -40.610 50.379 1.00 86.04 C +ATOM 8066 CE1 PHE E 56 37.700 -39.296 48.812 1.00120.26 C +ATOM 8067 CE2 PHE E 56 35.624 -40.464 49.024 1.00 96.91 C +ATOM 8068 CZ PHE E 56 36.561 -39.821 48.234 1.00109.35 C +ATOM 8069 N SER E 57 38.370 -42.188 54.980 1.00 95.48 N +ATOM 8070 CA SER E 57 38.347 -42.235 56.437 1.00 89.27 C +ATOM 8071 C SER E 57 39.766 -41.959 56.933 1.00 95.61 C +ATOM 8072 O SER E 57 40.700 -42.728 56.709 1.00 88.81 O +ATOM 8073 CB SER E 57 37.818 -43.576 56.943 1.00106.15 C +ATOM 8074 OG SER E 57 36.417 -43.645 56.781 1.00135.08 O +ATOM 8075 N THR E 58 39.918 -40.852 57.637 1.00113.17 N +ATOM 8076 CA THR E 58 41.199 -40.495 58.205 1.00139.07 C +ATOM 8077 C THR E 58 41.566 -41.428 59.328 1.00160.37 C +ATOM 8078 O THR E 58 40.716 -41.945 60.059 1.00255.41 O +ATOM 8079 CB THR E 58 41.153 -39.083 58.774 1.00164.56 C +ATOM 8080 OG1 THR E 58 40.156 -39.009 59.803 1.00172.78 O +ATOM 8081 CG2 THR E 58 40.774 -38.128 57.693 1.00198.45 C +ATOM 8082 N ALA E 59 42.841 -41.595 59.541 1.00133.86 N +ATOM 8083 CA ALA E 59 43.216 -42.499 60.598 1.00118.43 C +ATOM 8084 C ALA E 59 43.014 -41.879 61.983 1.00 94.49 C +ATOM 8085 O ALA E 59 42.944 -42.580 62.987 1.00 59.79 O +ATOM 8086 CB ALA E 59 44.636 -42.922 60.410 1.00122.06 C +ATOM 8087 N VAL E 60 42.918 -40.552 62.024 1.00 85.18 N +ATOM 8088 CA VAL E 60 42.876 -39.824 63.279 1.00 73.67 C +ATOM 8089 C VAL E 60 41.742 -38.809 63.201 1.00 93.27 C +ATOM 8090 O VAL E 60 41.543 -38.165 62.164 1.00120.59 O +ATOM 8091 CB VAL E 60 44.203 -39.082 63.489 1.00 76.24 C +ATOM 8092 CG1 VAL E 60 44.210 -38.257 64.776 1.00 64.52 C +ATOM 8093 CG2 VAL E 60 45.364 -40.071 63.472 1.00 81.10 C +ATOM 8094 N PRO E 61 40.980 -38.647 64.296 1.00105.72 N +ATOM 8095 CA PRO E 61 39.903 -37.635 64.284 1.00107.73 C +ATOM 8096 C PRO E 61 40.395 -36.193 64.131 1.00102.55 C +ATOM 8097 O PRO E 61 41.500 -35.856 64.606 1.00 83.68 O +ATOM 8098 CB PRO E 61 39.234 -37.807 65.640 1.00111.95 C +ATOM 8099 CG PRO E 61 40.278 -38.450 66.496 1.00150.10 C +ATOM 8100 CD PRO E 61 41.056 -39.354 65.581 1.00125.97 C +ATOM 8101 N GLN E 62 39.616 -35.386 63.408 1.00 91.97 N +ATOM 8102 CA GLN E 62 40.053 -34.035 62.998 1.00 97.41 C +ATOM 8103 C GLN E 62 39.696 -33.060 64.074 1.00119.79 C +ATOM 8104 O GLN E 62 39.301 -31.942 63.782 1.00158.38 O +ATOM 8105 CB GLN E 62 39.401 -33.608 61.669 1.00 74.56 C +ATOM 8106 CG GLN E 62 39.560 -34.617 60.538 1.00 74.65 C +ATOM 8107 CD GLN E 62 41.006 -34.891 60.214 1.00 88.63 C +ATOM 8108 OE1 GLN E 62 41.666 -34.090 59.589 1.00 72.86 O +ATOM 8109 NE2 GLN E 62 41.524 -36.009 60.710 1.00127.01 N +ATOM 8110 N SER E 63 39.750 -33.512 65.324 1.00117.02 N +ATOM 8111 CA SER E 63 39.039 -32.840 66.406 1.00136.23 C +ATOM 8112 C SER E 63 39.994 -32.345 67.500 1.00119.90 C +ATOM 8113 O SER E 63 39.553 -31.933 68.582 1.00119.88 O +ATOM 8114 CB SER E 63 37.944 -33.771 66.977 1.00141.07 C +ATOM 8115 OG SER E 63 38.465 -34.964 67.549 1.00128.19 O +ATOM 8116 N ALA E 64 41.289 -32.377 67.198 1.00 80.96 N +ATOM 8117 CA ALA E 64 42.315 -32.183 68.215 1.00 92.68 C +ATOM 8118 C ALA E 64 42.216 -30.814 68.864 1.00 85.80 C +ATOM 8119 O ALA E 64 42.401 -30.660 70.087 1.00 92.24 O +ATOM 8120 CB ALA E 64 43.664 -32.367 67.574 1.00 99.73 C +ATOM 8121 N THR E 65 41.858 -29.827 68.048 1.00 71.65 N +ATOM 8122 CA THR E 65 41.688 -28.442 68.514 1.00 59.21 C +ATOM 8123 C THR E 65 40.751 -28.311 69.707 1.00 72.47 C +ATOM 8124 O THR E 65 41.095 -27.716 70.725 1.00103.21 O +ATOM 8125 CB THR E 65 41.089 -27.608 67.422 1.00 58.06 C +ATOM 8126 OG1 THR E 65 41.631 -28.034 66.161 1.00 65.41 O +ATOM 8127 CG2 THR E 65 41.333 -26.138 67.675 1.00 48.82 C +ATOM 8128 N ALA E 66 39.589 -28.955 69.615 1.00101.00 N +ATOM 8129 CA ALA E 66 38.589 -28.856 70.665 1.00 92.25 C +ATOM 8130 C ALA E 66 39.029 -29.643 71.909 1.00 74.62 C +ATOM 8131 O ALA E 66 38.771 -29.220 73.046 1.00 79.04 O +ATOM 8132 CB ALA E 66 37.247 -29.339 70.157 1.00 82.95 C +ATOM 8133 N MET E 67 39.740 -30.736 71.683 1.00 59.94 N +ATOM 8134 CA MET E 67 40.260 -31.509 72.781 1.00 84.59 C +ATOM 8135 C MET E 67 41.255 -30.667 73.571 1.00 81.86 C +ATOM 8136 O MET E 67 41.310 -30.752 74.824 1.00130.50 O +ATOM 8137 CB MET E 67 40.935 -32.808 72.276 1.00 99.87 C +ATOM 8138 CG MET E 67 39.983 -33.875 71.727 1.00114.14 C +ATOM 8139 SD MET E 67 40.884 -35.193 70.855 1.00 59.64 S +ATOM 8140 CE MET E 67 39.552 -36.332 70.499 1.00 94.35 C +ATOM 8141 N LEU E 68 42.114 -29.957 72.848 1.00 62.15 N +ATOM 8142 CA LEU E 68 43.137 -29.169 73.494 1.00 71.62 C +ATOM 8143 C LEU E 68 42.517 -28.054 74.301 1.00 73.80 C +ATOM 8144 O LEU E 68 42.918 -27.822 75.445 1.00139.03 O +ATOM 8145 CB LEU E 68 44.101 -28.557 72.494 1.00 80.50 C +ATOM 8146 CG LEU E 68 45.048 -27.509 73.122 1.00102.74 C +ATOM 8147 CD1 LEU E 68 46.032 -28.159 74.120 1.00 89.54 C +ATOM 8148 CD2 LEU E 68 45.816 -26.740 72.062 1.00111.20 C +ATOM 8149 N VAL E 69 41.535 -27.385 73.734 1.00 78.46 N +ATOM 8150 CA VAL E 69 40.840 -26.319 74.451 1.00 97.22 C +ATOM 8151 C VAL E 69 40.229 -26.876 75.739 1.00 97.93 C +ATOM 8152 O VAL E 69 40.304 -26.255 76.802 1.00 94.26 O +ATOM 8153 CB VAL E 69 39.710 -25.647 73.591 1.00 91.23 C +ATOM 8154 CG1 VAL E 69 38.910 -24.664 74.434 1.00 66.01 C +ATOM 8155 CG2 VAL E 69 40.297 -24.923 72.380 1.00106.01 C +ATOM 8156 N THR E 70 39.601 -28.040 75.622 1.00 97.75 N +ATOM 8157 CA THR E 70 38.937 -28.671 76.757 1.00111.77 C +ATOM 8158 C THR E 70 39.947 -29.019 77.838 1.00107.28 C +ATOM 8159 O THR E 70 39.729 -28.780 79.025 1.00107.01 O +ATOM 8160 CB THR E 70 38.161 -29.931 76.310 1.00105.56 C +ATOM 8161 OG1 THR E 70 37.239 -29.551 75.277 1.00156.84 O +ATOM 8162 CG2 THR E 70 37.398 -30.549 77.486 1.00 93.28 C +ATOM 8163 N ALA E 71 41.061 -29.597 77.422 1.00104.45 N +ATOM 8164 CA ALA E 71 42.108 -29.946 78.365 1.00104.38 C +ATOM 8165 C ALA E 71 42.611 -28.684 79.073 1.00 84.82 C +ATOM 8166 O ALA E 71 42.923 -28.701 80.268 1.00 87.81 O +ATOM 8167 CB ALA E 71 43.245 -30.701 77.645 1.00102.15 C +ATOM 8168 N LEU E 72 42.812 -27.625 78.299 1.00 91.40 N +ATOM 8169 CA LEU E 72 43.330 -26.377 78.850 1.00111.06 C +ATOM 8170 C LEU E 72 42.361 -25.848 79.894 1.00113.88 C +ATOM 8171 O LEU E 72 42.766 -25.082 80.781 1.00101.27 O +ATOM 8172 CB LEU E 72 43.548 -25.330 77.744 1.00124.23 C +ATOM 8173 CG LEU E 72 44.707 -25.617 76.784 1.00105.99 C +ATOM 8174 CD1 LEU E 72 44.513 -24.771 75.535 1.00130.94 C +ATOM 8175 CD2 LEU E 72 46.059 -25.359 77.408 1.00 60.99 C +ATOM 8176 N LYS E 73 41.086 -26.209 79.768 1.00 96.12 N +ATOM 8177 CA LYS E 73 40.089 -25.703 80.703 1.00103.11 C +ATOM 8178 C LYS E 73 40.057 -26.568 81.930 1.00 80.90 C +ATOM 8179 O LYS E 73 39.982 -26.051 83.045 1.00 90.13 O +ATOM 8180 CB LYS E 73 38.700 -25.642 80.067 1.00127.31 C +ATOM 8181 CG LYS E 73 37.656 -24.875 80.892 1.00131.91 C +ATOM 8182 CD LYS E 73 36.282 -24.848 80.185 1.00116.62 C +ATOM 8183 CE LYS E 73 35.131 -24.736 81.164 1.00120.74 C +ATOM 8184 NZ LYS E 73 34.395 -23.452 81.038 1.00119.83 N +ATOM 8185 N ASP E 74 40.081 -27.877 81.720 1.00 69.95 N +ATOM 8186 CA ASP E 74 39.951 -28.816 82.826 1.00 92.88 C +ATOM 8187 C ASP E 74 41.100 -28.679 83.829 1.00 77.35 C +ATOM 8188 O ASP E 74 40.925 -28.941 85.023 1.00 65.17 O +ATOM 8189 CB ASP E 74 39.894 -30.261 82.307 1.00104.64 C +ATOM 8190 CG ASP E 74 38.589 -30.583 81.556 1.00118.85 C +ATOM 8191 OD1 ASP E 74 37.518 -29.978 81.851 1.00133.20 O +ATOM 8192 OD2 ASP E 74 38.643 -31.479 80.686 1.00 86.49 O +ATOM 8193 N SER E 75 42.250 -28.230 83.344 1.00 80.56 N +ATOM 8194 CA SER E 75 43.457 -28.078 84.177 1.00 71.72 C +ATOM 8195 C SER E 75 43.289 -27.030 85.276 1.00 79.47 C +ATOM 8196 O SER E 75 43.981 -27.084 86.287 1.00 89.41 O +ATOM 8197 CB SER E 75 44.666 -27.695 83.311 1.00 64.06 C +ATOM 8198 OG SER E 75 44.730 -26.292 83.106 1.00 53.51 O +ATOM 8199 N ARG E 76 42.391 -26.067 85.048 1.00 95.59 N +ATOM 8200 CA ARG E 76 42.129 -24.945 85.966 1.00 97.19 C +ATOM 8201 C ARG E 76 43.352 -24.080 86.106 1.00 99.95 C +ATOM 8202 O ARG E 76 43.656 -23.564 87.178 1.00117.98 O +ATOM 8203 CB ARG E 76 41.663 -25.440 87.327 1.00107.40 C +ATOM 8204 CG ARG E 76 40.359 -26.225 87.304 1.00121.16 C +ATOM 8205 CD ARG E 76 39.967 -26.637 88.717 1.00152.04 C +ATOM 8206 NE ARG E 76 40.880 -27.654 89.254 1.00224.61 N +ATOM 8207 CZ ARG E 76 41.956 -27.412 90.008 1.00242.13 C +ATOM 8208 NH1 ARG E 76 42.295 -26.171 90.348 1.00241.88 N +ATOM 8209 NH2 ARG E 76 42.702 -28.428 90.424 1.00232.36 N +ATOM 8210 N TRP E 77 44.079 -23.967 85.008 1.00107.36 N +ATOM 8211 CA TRP E 77 45.177 -23.020 84.902 1.00131.92 C +ATOM 8212 C TRP E 77 44.828 -21.910 83.891 1.00134.10 C +ATOM 8213 O TRP E 77 45.283 -20.770 84.014 1.00139.84 O +ATOM 8214 CB TRP E 77 46.449 -23.763 84.472 1.00128.54 C +ATOM 8215 CG TRP E 77 47.281 -24.213 85.596 1.00120.57 C +ATOM 8216 CD1 TRP E 77 47.045 -25.270 86.407 1.00144.43 C +ATOM 8217 CD2 TRP E 77 48.519 -23.640 86.032 1.00129.04 C +ATOM 8218 NE1 TRP E 77 48.060 -25.401 87.321 1.00173.49 N +ATOM 8219 CE2 TRP E 77 48.979 -24.409 87.110 1.00142.83 C +ATOM 8220 CE3 TRP E 77 49.285 -22.556 85.612 1.00136.44 C +ATOM 8221 CZ2 TRP E 77 50.175 -24.127 87.778 1.00126.86 C +ATOM 8222 CZ3 TRP E 77 50.466 -22.268 86.291 1.00122.00 C +ATOM 8223 CH2 TRP E 77 50.896 -23.050 87.359 1.00110.07 C +ATOM 8224 N PHE E 78 44.069 -22.278 82.859 1.00101.97 N +ATOM 8225 CA PHE E 78 43.820 -21.415 81.719 1.00 74.47 C +ATOM 8226 C PHE E 78 42.323 -21.158 81.545 1.00 88.70 C +ATOM 8227 O PHE E 78 41.498 -22.086 81.668 1.00111.81 O +ATOM 8228 CB PHE E 78 44.350 -22.079 80.435 1.00 78.52 C +ATOM 8229 CG PHE E 78 45.807 -22.447 80.483 1.00 67.49 C +ATOM 8230 CD1 PHE E 78 46.784 -21.480 80.379 1.00 73.80 C +ATOM 8231 CD2 PHE E 78 46.180 -23.768 80.549 1.00 79.52 C +ATOM 8232 CE1 PHE E 78 48.116 -21.811 80.417 1.00 85.48 C +ATOM 8233 CE2 PHE E 78 47.510 -24.115 80.598 1.00 96.76 C +ATOM 8234 CZ PHE E 78 48.482 -23.135 80.522 1.00 98.95 C +ATOM 8235 N ILE E 79 41.996 -19.939 81.130 1.00 84.17 N +ATOM 8236 CA ILE E 79 40.710 -19.620 80.517 1.00 99.94 C +ATOM 8237 C ILE E 79 40.892 -19.632 79.002 1.00 97.67 C +ATOM 8238 O ILE E 79 41.784 -18.958 78.476 1.00104.85 O +ATOM 8239 CB ILE E 79 40.261 -18.210 80.912 1.00127.13 C +ATOM 8240 CG1 ILE E 79 40.397 -18.005 82.419 1.00149.65 C +ATOM 8241 CG2 ILE E 79 38.823 -17.957 80.478 1.00143.29 C +ATOM 8242 CD1 ILE E 79 40.523 -16.550 82.826 1.00150.34 C +ATOM 8243 N PRO E 80 40.106 -20.459 78.299 1.00 97.65 N +ATOM 8244 CA PRO E 80 40.274 -20.433 76.868 1.00 91.15 C +ATOM 8245 C PRO E 80 39.339 -19.417 76.261 1.00 69.61 C +ATOM 8246 O PRO E 80 38.179 -19.356 76.627 1.00 51.49 O +ATOM 8247 CB PRO E 80 39.902 -21.851 76.441 1.00 93.48 C +ATOM 8248 CG PRO E 80 40.125 -22.671 77.648 1.00 94.34 C +ATOM 8249 CD PRO E 80 39.625 -21.773 78.743 1.00106.37 C +ATOM 8250 N LEU E 81 39.875 -18.616 75.358 1.00 56.95 N +ATOM 8251 CA LEU E 81 39.081 -17.722 74.593 1.00 50.81 C +ATOM 8252 C LEU E 81 38.728 -18.419 73.284 1.00 48.08 C +ATOM 8253 O LEU E 81 39.533 -19.154 72.691 1.00 35.06 O +ATOM 8254 CB LEU E 81 39.852 -16.449 74.378 1.00 64.74 C +ATOM 8255 CG LEU E 81 40.318 -15.857 75.701 1.00 92.64 C +ATOM 8256 CD1 LEU E 81 41.205 -14.662 75.417 1.00112.26 C +ATOM 8257 CD2 LEU E 81 39.135 -15.447 76.549 1.00 96.35 C +ATOM 8258 N GLU E 82 37.488 -18.195 72.867 1.00 62.29 N +ATOM 8259 CA GLU E 82 36.913 -18.827 71.659 1.00 64.32 C +ATOM 8260 C GLU E 82 37.457 -18.121 70.415 1.00 83.62 C +ATOM 8261 O GLU E 82 37.040 -16.972 70.084 1.00109.71 O +ATOM 8262 CB GLU E 82 35.344 -18.836 71.679 1.00 47.54 C +ATOM 8263 CG GLU E 82 34.685 -19.425 70.454 1.00 38.22 C +ATOM 8264 CD GLU E 82 34.881 -20.936 70.268 1.00 51.70 C +ATOM 8265 OE1 GLU E 82 36.015 -21.503 70.407 1.00 91.23 O +ATOM 8266 OE2 GLU E 82 33.891 -21.635 69.980 1.00 66.78 O +ATOM 8267 N ARG E 83 38.360 -18.822 69.723 1.00 64.24 N +ATOM 8268 CA ARG E 83 38.794 -18.420 68.397 1.00 67.10 C +ATOM 8269 C ARG E 83 38.439 -19.420 67.253 1.00107.45 C +ATOM 8270 O ARG E 83 38.456 -19.062 66.075 1.00140.95 O +ATOM 8271 CB ARG E 83 40.277 -18.160 68.453 1.00 45.75 C +ATOM 8272 CG ARG E 83 40.648 -17.174 69.512 1.00 43.18 C +ATOM 8273 CD ARG E 83 40.194 -15.781 69.202 1.00 56.21 C +ATOM 8274 NE ARG E 83 40.841 -14.897 70.188 1.00 69.23 N +ATOM 8275 CZ ARG E 83 40.242 -14.314 71.241 1.00 68.91 C +ATOM 8276 NH1 ARG E 83 38.928 -14.488 71.456 1.00 80.13 N +ATOM 8277 NH2 ARG E 83 40.966 -13.517 72.046 1.00 53.65 N +ATOM 8278 N GLN E 84 38.102 -20.662 67.580 1.00134.94 N +ATOM 8279 CA GLN E 84 37.764 -21.654 66.556 1.00106.20 C +ATOM 8280 C GLN E 84 36.441 -21.421 65.803 1.00 66.95 C +ATOM 8281 O GLN E 84 36.024 -22.164 64.873 1.00 55.48 O +ATOM 8282 CB GLN E 84 37.504 -22.971 67.257 1.00127.59 C +ATOM 8283 CG GLN E 84 36.883 -23.938 66.209 1.00143.17 C +ATOM 8284 CD GLN E 84 37.637 -25.214 65.905 1.00134.91 C +ATOM 8285 OE1 GLN E 84 38.771 -25.415 66.313 1.00132.59 O +ATOM 8286 NE2 GLN E 84 36.988 -26.076 65.143 1.00129.05 N +ATOM 8287 N GLY E 85 35.633 -20.634 66.413 1.00 54.90 N +ATOM 8288 CA GLY E 85 34.544 -20.117 65.656 1.00 93.51 C +ATOM 8289 C GLY E 85 34.433 -18.602 65.641 1.00 95.81 C +ATOM 8290 O GLY E 85 33.316 -18.063 65.824 1.00 91.73 O +ATOM 8291 N LEU E 86 35.563 -17.912 65.517 1.00 57.52 N +ATOM 8292 CA LEU E 86 35.590 -16.496 65.860 1.00 64.98 C +ATOM 8293 C LEU E 86 34.602 -15.749 64.995 1.00 72.74 C +ATOM 8294 O LEU E 86 34.035 -14.716 65.399 1.00106.76 O +ATOM 8295 CB LEU E 86 37.002 -15.929 65.673 1.00 97.93 C +ATOM 8296 CG LEU E 86 37.275 -14.396 65.744 1.00 96.35 C +ATOM 8297 CD1 LEU E 86 36.889 -13.778 67.078 1.00 55.25 C +ATOM 8298 CD2 LEU E 86 38.752 -14.126 65.441 1.00108.38 C +ATOM 8299 N GLN E 87 34.438 -16.215 63.761 1.00 88.51 N +ATOM 8300 CA GLN E 87 33.629 -15.488 62.775 1.00110.68 C +ATOM 8301 C GLN E 87 32.152 -15.359 63.240 1.00105.31 C +ATOM 8302 O GLN E 87 31.544 -14.276 63.164 1.00 61.44 O +ATOM 8303 CB GLN E 87 33.737 -16.169 61.401 1.00113.87 C +ATOM 8304 CG GLN E 87 33.673 -15.200 60.226 1.00117.65 C +ATOM 8305 CD GLN E 87 34.503 -13.927 60.430 1.00114.17 C +ATOM 8306 OE1 GLN E 87 35.714 -13.986 60.649 1.00 95.02 O +ATOM 8307 NE2 GLN E 87 33.848 -12.768 60.336 1.00101.17 N +ATOM 8308 N ASN E 88 31.633 -16.445 63.814 1.00103.99 N +ATOM 8309 CA ASN E 88 30.279 -16.460 64.347 1.00 95.86 C +ATOM 8310 C ASN E 88 30.126 -15.564 65.564 1.00 82.71 C +ATOM 8311 O ASN E 88 29.088 -14.909 65.743 1.00 71.75 O +ATOM 8312 CB ASN E 88 29.911 -17.866 64.780 1.00 99.56 C +ATOM 8313 CG ASN E 88 30.077 -18.856 63.673 1.00 89.48 C +ATOM 8314 OD1 ASN E 88 29.737 -18.551 62.518 1.00128.25 O +ATOM 8315 ND2 ASN E 88 30.561 -20.043 63.998 1.00 56.49 N +ATOM 8316 N LEU E 89 31.162 -15.552 66.401 1.00 64.39 N +ATOM 8317 CA LEU E 89 31.190 -14.695 67.555 1.00 57.22 C +ATOM 8318 C LEU E 89 31.063 -13.207 67.135 1.00 74.28 C +ATOM 8319 O LEU E 89 30.261 -12.425 67.681 1.00 79.12 O +ATOM 8320 CB LEU E 89 32.485 -14.933 68.284 1.00 57.33 C +ATOM 8321 CG LEU E 89 32.502 -14.747 69.792 1.00 83.37 C +ATOM 8322 CD1 LEU E 89 33.410 -13.612 70.204 1.00 83.79 C +ATOM 8323 CD2 LEU E 89 31.117 -14.521 70.375 1.00 89.10 C +ATOM 8324 N LEU E 90 31.782 -12.838 66.078 1.00 93.52 N +ATOM 8325 CA LEU E 90 31.779 -11.451 65.589 1.00 87.18 C +ATOM 8326 C LEU E 90 30.440 -11.110 64.950 1.00 84.20 C +ATOM 8327 O LEU E 90 29.984 -9.956 64.975 1.00 75.38 O +ATOM 8328 CB LEU E 90 32.910 -11.234 64.591 1.00 82.40 C +ATOM 8329 CG LEU E 90 34.299 -11.464 65.164 1.00 99.18 C +ATOM 8330 CD1 LEU E 90 35.293 -11.698 64.030 1.00117.96 C +ATOM 8331 CD2 LEU E 90 34.699 -10.279 66.044 1.00 95.80 C +ATOM 8332 N ASN E 91 29.809 -12.130 64.386 1.00 74.18 N +ATOM 8333 CA ASN E 91 28.534 -11.942 63.768 1.00 80.44 C +ATOM 8334 C ASN E 91 27.495 -11.639 64.822 1.00 69.73 C +ATOM 8335 O ASN E 91 26.647 -10.759 64.634 1.00 93.73 O +ATOM 8336 CB ASN E 91 28.160 -13.163 62.918 1.00 99.62 C +ATOM 8337 CG ASN E 91 27.764 -12.749 61.507 1.00104.44 C +ATOM 8338 OD1 ASN E 91 28.523 -12.021 60.868 1.00 84.44 O +ATOM 8339 ND2 ASN E 91 26.519 -13.048 61.090 1.00102.05 N +ATOM 8340 N GLU E 92 27.465 -12.454 65.866 1.00 62.84 N +ATOM 8341 CA GLU E 92 26.460 -12.275 66.913 1.00 73.90 C +ATOM 8342 C GLU E 92 26.637 -10.891 67.486 1.00 60.49 C +ATOM 8343 O GLU E 92 25.644 -10.255 67.897 1.00116.29 O +ATOM 8344 CB GLU E 92 26.563 -13.352 68.021 1.00 82.91 C +ATOM 8345 CG GLU E 92 25.664 -14.566 67.849 1.00 77.15 C +ATOM 8346 CD GLU E 92 24.201 -14.197 67.628 1.00 89.67 C +ATOM 8347 OE1 GLU E 92 23.577 -13.534 68.513 1.00119.71 O +ATOM 8348 OE2 GLU E 92 23.643 -14.635 66.576 1.00 66.08 O +ATOM 8349 N ARG E 93 27.874 -10.446 67.567 1.00 40.08 N +ATOM 8350 CA ARG E 93 28.127 -9.144 68.119 1.00 57.06 C +ATOM 8351 C ARG E 93 27.657 -8.039 67.162 1.00 79.64 C +ATOM 8352 O ARG E 93 27.154 -6.993 67.592 1.00 78.53 O +ATOM 8353 CB ARG E 93 29.596 -9.025 68.461 1.00 77.75 C +ATOM 8354 CG ARG E 93 29.970 -9.900 69.651 1.00 80.26 C +ATOM 8355 CD ARG E 93 31.467 -10.102 69.823 1.00 97.65 C +ATOM 8356 NE ARG E 93 32.028 -9.242 70.860 1.00124.56 N +ATOM 8357 CZ ARG E 93 32.616 -8.061 70.648 1.00123.69 C +ATOM 8358 NH1 ARG E 93 32.768 -7.563 69.426 1.00 93.95 N +ATOM 8359 NH2 ARG E 93 33.113 -7.414 71.686 1.00157.71 N +ATOM 8360 N LYS E 94 27.703 -8.303 65.855 1.00108.11 N +ATOM 8361 CA LYS E 94 27.095 -7.382 64.863 1.00108.74 C +ATOM 8362 C LYS E 94 25.583 -7.309 65.029 1.00 81.16 C +ATOM 8363 O LYS E 94 25.008 -6.197 65.014 1.00 77.87 O +ATOM 8364 CB LYS E 94 27.356 -7.837 63.438 1.00123.68 C +ATOM 8365 CG LYS E 94 28.658 -7.354 62.826 1.00148.08 C +ATOM 8366 CD LYS E 94 28.881 -8.047 61.489 1.00166.57 C +ATOM 8367 CE LYS E 94 29.867 -7.313 60.596 1.00174.77 C +ATOM 8368 NZ LYS E 94 30.303 -8.193 59.478 1.00173.49 N +ATOM 8369 N ILE E 95 24.961 -8.470 65.275 1.00 51.39 N +ATOM 8370 CA ILE E 95 23.524 -8.508 65.464 1.00 56.80 C +ATOM 8371 C ILE E 95 23.069 -7.780 66.739 1.00 67.53 C +ATOM 8372 O ILE E 95 22.011 -7.083 66.738 1.00 66.61 O +ATOM 8373 CB ILE E 95 22.940 -9.918 65.481 1.00 47.74 C +ATOM 8374 CG1 ILE E 95 23.497 -10.711 64.335 1.00 53.98 C +ATOM 8375 CG2 ILE E 95 21.436 -9.823 65.310 1.00 54.64 C +ATOM 8376 CD1 ILE E 95 22.766 -12.010 64.057 1.00 66.31 C +ATOM 8377 N ILE E 96 23.838 -7.990 67.811 1.00 60.00 N +ATOM 8378 CA ILE E 96 23.635 -7.289 69.069 1.00 60.95 C +ATOM 8379 C ILE E 96 23.684 -5.814 68.838 1.00 54.19 C +ATOM 8380 O ILE E 96 22.716 -5.106 69.111 1.00 48.68 O +ATOM 8381 CB ILE E 96 24.690 -7.646 70.117 1.00 82.38 C +ATOM 8382 CG1 ILE E 96 24.506 -9.105 70.553 1.00131.28 C +ATOM 8383 CG2 ILE E 96 24.520 -6.775 71.338 1.00 82.52 C +ATOM 8384 CD1 ILE E 96 25.463 -9.541 71.645 1.00163.72 C +ATOM 8385 N ARG E 97 24.816 -5.341 68.342 1.00 72.16 N +ATOM 8386 CA ARG E 97 25.004 -3.899 68.127 1.00 93.09 C +ATOM 8387 C ARG E 97 23.923 -3.291 67.211 1.00 83.84 C +ATOM 8388 O ARG E 97 23.540 -2.118 67.368 1.00 72.56 O +ATOM 8389 CB ARG E 97 26.395 -3.599 67.547 1.00102.85 C +ATOM 8390 CG ARG E 97 27.402 -3.086 68.554 1.00101.66 C +ATOM 8391 CD ARG E 97 28.728 -2.758 67.887 1.00104.07 C +ATOM 8392 NE ARG E 97 29.551 -3.958 67.688 1.00 96.46 N +ATOM 8393 CZ ARG E 97 30.583 -4.317 68.467 1.00 75.93 C +ATOM 8394 NH1 ARG E 97 30.939 -3.600 69.536 1.00 54.22 N +ATOM 8395 NH2 ARG E 97 31.241 -5.424 68.189 1.00 81.01 N +ATOM 8396 N ALA E 98 23.430 -4.086 66.262 1.00 77.01 N +ATOM 8397 CA ALA E 98 22.378 -3.626 65.372 1.00 92.37 C +ATOM 8398 C ALA E 98 21.021 -3.612 66.088 1.00111.02 C +ATOM 8399 O ALA E 98 20.155 -2.777 65.769 1.00 97.34 O +ATOM 8400 CB ALA E 98 22.313 -4.509 64.153 1.00 90.52 C +ATOM 8401 N ALA E 99 20.867 -4.499 67.079 1.00105.10 N +ATOM 8402 CA ALA E 99 19.648 -4.556 67.894 1.00 89.04 C +ATOM 8403 C ALA E 99 19.451 -3.332 68.785 1.00 96.74 C +ATOM 8404 O ALA E 99 18.387 -2.699 68.790 1.00146.50 O +ATOM 8405 CB ALA E 99 19.663 -5.782 68.757 1.00 78.95 C +ATOM 8406 N GLN E 100 20.490 -2.979 69.533 1.00 93.24 N +ATOM 8407 CA GLN E 100 20.346 -2.030 70.643 1.00101.14 C +ATOM 8408 C GLN E 100 20.899 -0.635 70.377 1.00 95.05 C +ATOM 8409 O GLN E 100 20.926 0.205 71.275 1.00113.97 O +ATOM 8410 CB GLN E 100 20.969 -2.610 71.923 1.00 97.39 C +ATOM 8411 CG GLN E 100 22.315 -3.286 71.736 1.00 88.42 C +ATOM 8412 CD GLN E 100 22.587 -4.393 72.750 1.00 86.78 C +ATOM 8413 OE1 GLN E 100 21.840 -5.387 72.867 1.00 67.78 O +ATOM 8414 NE2 GLN E 100 23.674 -4.229 73.483 1.00 99.28 N +ATOM 8415 N GLU E 101 21.302 -0.374 69.143 1.00 93.98 N +ATOM 8416 CA GLU E 101 21.884 0.923 68.805 1.00105.60 C +ATOM 8417 C GLU E 101 20.869 2.064 68.875 1.00110.86 C +ATOM 8418 O GLU E 101 21.251 3.230 69.029 1.00 89.81 O +ATOM 8419 CB GLU E 101 22.540 0.876 67.417 1.00119.68 C +ATOM 8420 CG GLU E 101 21.649 0.341 66.298 1.00113.37 C +ATOM 8421 CD GLU E 101 22.328 0.389 64.934 1.00110.94 C +ATOM 8422 OE1 GLU E 101 23.569 0.526 64.893 1.00113.88 O +ATOM 8423 OE2 GLU E 101 21.622 0.313 63.902 1.00126.11 O +ATOM 8424 N ASN E 102 19.581 1.742 68.728 1.00115.36 N +ATOM 8425 CA ASN E 102 18.537 2.771 68.693 1.00115.55 C +ATOM 8426 C ASN E 102 17.939 3.039 70.068 1.00134.53 C +ATOM 8427 O ASN E 102 17.097 3.924 70.216 1.00153.42 O +ATOM 8428 CB ASN E 102 17.410 2.376 67.741 1.00108.12 C +ATOM 8429 CG ASN E 102 17.801 2.482 66.283 1.00107.90 C +ATOM 8430 OD1 ASN E 102 17.893 3.575 65.721 1.00 71.12 O +ATOM 8431 ND2 ASN E 102 18.147 1.340 65.700 1.00134.61 N +ATOM 8432 N GLY E 103 18.379 2.297 71.081 1.00141.85 N +ATOM 8433 CA GLY E 103 17.884 2.508 72.446 1.00123.19 C +ATOM 8434 C GLY E 103 16.392 2.290 72.584 1.00107.29 C +ATOM 8435 O GLY E 103 15.715 2.955 73.364 1.00 98.76 O +ATOM 8436 N THR E 104 15.868 1.366 71.798 1.00115.36 N +ATOM 8437 CA THR E 104 14.520 0.907 72.005 1.00113.02 C +ATOM 8438 C THR E 104 14.558 -0.410 72.771 1.00119.01 C +ATOM 8439 O THR E 104 13.614 -0.718 73.487 1.00119.56 O +ATOM 8440 CB THR E 104 13.736 0.750 70.678 1.00113.11 C +ATOM 8441 OG1 THR E 104 14.321 -0.277 69.858 1.00 90.38 O +ATOM 8442 CG2 THR E 104 13.708 2.072 69.925 1.00 96.24 C +ATOM 8443 N VAL E 105 15.644 -1.177 72.649 1.00131.52 N +ATOM 8444 CA VAL E 105 15.656 -2.552 73.181 1.00149.93 C +ATOM 8445 C VAL E 105 15.456 -2.548 74.692 1.00143.97 C +ATOM 8446 O VAL E 105 15.962 -1.667 75.399 1.00131.74 O +ATOM 8447 CB VAL E 105 16.928 -3.362 72.789 1.00162.94 C +ATOM 8448 CG1 VAL E 105 17.342 -4.334 73.891 1.00151.87 C +ATOM 8449 CG2 VAL E 105 16.705 -4.135 71.477 1.00163.89 C +ATOM 8450 N ALA E 106 14.656 -3.515 75.153 1.00146.80 N +ATOM 8451 CA ALA E 106 14.183 -3.577 76.531 1.00147.56 C +ATOM 8452 C ALA E 106 15.348 -3.736 77.500 1.00152.61 C +ATOM 8453 O ALA E 106 16.246 -4.545 77.271 1.00181.40 O +ATOM 8454 CB ALA E 106 13.202 -4.730 76.690 1.00144.92 C +ATOM 8455 N ILE E 107 15.328 -2.950 78.575 1.00139.53 N +ATOM 8456 CA ILE E 107 16.452 -2.871 79.516 1.00129.63 C +ATOM 8457 C ILE E 107 16.802 -4.238 80.147 1.00111.96 C +ATOM 8458 O ILE E 107 17.956 -4.517 80.469 1.00 74.13 O +ATOM 8459 CB ILE E 107 16.166 -1.813 80.616 1.00121.95 C +ATOM 8460 CG1 ILE E 107 17.435 -1.500 81.427 1.00108.11 C +ATOM 8461 CG2 ILE E 107 15.038 -2.282 81.532 1.00119.14 C +ATOM 8462 CD1 ILE E 107 18.608 -1.003 80.609 1.00 99.01 C +ATOM 8463 N ASN E 108 15.794 -5.086 80.302 1.00136.40 N +ATOM 8464 CA ASN E 108 15.997 -6.455 80.791 1.00160.10 C +ATOM 8465 C ASN E 108 16.717 -7.307 79.750 1.00148.20 C +ATOM 8466 O ASN E 108 17.483 -8.202 80.081 1.00141.67 O +ATOM 8467 CB ASN E 108 14.646 -7.106 81.130 1.00171.14 C +ATOM 8468 CG ASN E 108 13.608 -6.096 81.593 1.00175.56 C +ATOM 8469 OD1 ASN E 108 13.532 -5.771 82.779 1.00215.01 O +ATOM 8470 ND2 ASN E 108 12.798 -5.598 80.658 1.00146.45 N +ATOM 8471 N ASN E 109 16.397 -7.052 78.490 1.00130.99 N +ATOM 8472 CA ASN E 109 16.869 -7.862 77.385 1.00120.09 C +ATOM 8473 C ASN E 109 18.237 -7.419 76.882 1.00127.58 C +ATOM 8474 O ASN E 109 18.903 -8.156 76.149 1.00146.49 O +ATOM 8475 CB ASN E 109 15.846 -7.821 76.243 1.00114.79 C +ATOM 8476 CG ASN E 109 15.259 -9.185 75.952 1.00123.34 C +ATOM 8477 OD1 ASN E 109 15.470 -9.751 74.878 1.00130.78 O +ATOM 8478 ND2 ASN E 109 14.543 -9.737 76.922 1.00140.31 N +ATOM 8479 N ARG E 110 18.627 -6.198 77.253 1.00114.93 N +ATOM 8480 CA ARG E 110 19.839 -5.538 76.731 1.00100.87 C +ATOM 8481 C ARG E 110 21.083 -6.386 76.977 1.00107.00 C +ATOM 8482 O ARG E 110 21.253 -6.939 78.074 1.00156.81 O +ATOM 8483 CB ARG E 110 20.013 -4.184 77.426 1.00 95.39 C +ATOM 8484 CG ARG E 110 20.853 -3.180 76.672 1.00104.35 C +ATOM 8485 CD ARG E 110 20.367 -1.759 76.885 1.00115.69 C +ATOM 8486 NE ARG E 110 21.017 -1.141 78.049 1.00131.92 N +ATOM 8487 CZ ARG E 110 21.757 -0.024 78.020 1.00133.42 C +ATOM 8488 NH1 ARG E 110 21.969 0.645 76.879 1.00105.27 N +ATOM 8489 NH2 ARG E 110 22.263 0.451 79.158 1.00129.85 N +ATOM 8490 N ILE E 111 21.940 -6.520 75.967 1.00 83.71 N +ATOM 8491 CA ILE E 111 23.201 -7.230 76.153 1.00 78.39 C +ATOM 8492 C ILE E 111 24.342 -6.254 76.141 1.00 84.62 C +ATOM 8493 O ILE E 111 24.585 -5.642 75.117 1.00 88.69 O +ATOM 8494 CB ILE E 111 23.445 -8.280 75.069 1.00 79.82 C +ATOM 8495 CG1 ILE E 111 22.373 -9.373 75.164 1.00106.34 C +ATOM 8496 CG2 ILE E 111 24.830 -8.904 75.236 1.00 76.45 C +ATOM 8497 CD1 ILE E 111 22.323 -10.318 73.975 1.00113.95 C +ATOM 8498 N PRO E 112 25.082 -6.143 77.265 1.00108.13 N +ATOM 8499 CA PRO E 112 26.176 -5.191 77.332 1.00106.86 C +ATOM 8500 C PRO E 112 27.426 -5.756 76.661 1.00129.63 C +ATOM 8501 O PRO E 112 27.831 -6.898 76.940 1.00 98.84 O +ATOM 8502 CB PRO E 112 26.398 -5.026 78.832 1.00110.73 C +ATOM 8503 CG PRO E 112 26.037 -6.359 79.402 1.00114.41 C +ATOM 8504 CD PRO E 112 25.016 -6.978 78.481 1.00118.03 C +ATOM 8505 N LEU E 113 28.006 -4.968 75.756 1.00137.97 N +ATOM 8506 CA LEU E 113 29.112 -5.433 74.926 1.00 98.22 C +ATOM 8507 C LEU E 113 30.423 -4.827 75.358 1.00 82.71 C +ATOM 8508 O LEU E 113 30.524 -3.632 75.693 1.00 61.47 O +ATOM 8509 CB LEU E 113 28.856 -5.138 73.458 1.00 87.62 C +ATOM 8510 CG LEU E 113 28.049 -6.199 72.712 1.00 92.01 C +ATOM 8511 CD1 LEU E 113 27.966 -5.796 71.253 1.00 92.29 C +ATOM 8512 CD2 LEU E 113 28.668 -7.585 72.852 1.00101.67 C +ATOM 8513 N GLN E 114 31.430 -5.684 75.334 1.00 70.84 N +ATOM 8514 CA GLN E 114 32.725 -5.370 75.899 1.00 81.55 C +ATOM 8515 C GLN E 114 33.720 -5.903 74.918 1.00 94.30 C +ATOM 8516 O GLN E 114 33.403 -6.852 74.186 1.00154.05 O +ATOM 8517 CB GLN E 114 32.896 -6.084 77.219 1.00 78.83 C +ATOM 8518 CG GLN E 114 33.803 -5.376 78.204 1.00 75.44 C +ATOM 8519 CD GLN E 114 34.476 -6.347 79.158 1.00 67.24 C +ATOM 8520 OE1 GLN E 114 35.550 -6.061 79.698 1.00 60.16 O +ATOM 8521 NE2 GLN E 114 33.812 -7.480 79.415 1.00 64.05 N +ATOM 8522 N SER E 115 34.855 -5.222 74.791 1.00 73.95 N +ATOM 8523 CA SER E 115 35.814 -5.564 73.755 1.00 78.50 C +ATOM 8524 C SER E 115 36.193 -7.024 73.927 1.00 87.07 C +ATOM 8525 O SER E 115 36.105 -7.564 75.065 1.00116.45 O +ATOM 8526 CB SER E 115 37.033 -4.651 73.848 1.00 78.33 C +ATOM 8527 OG SER E 115 37.528 -4.577 75.175 1.00 88.43 O +ATOM 8528 N LEU E 116 36.611 -7.683 72.840 1.00 66.43 N +ATOM 8529 CA LEU E 116 36.841 -9.117 72.966 1.00 74.27 C +ATOM 8530 C LEU E 116 38.048 -9.348 73.880 1.00 85.20 C +ATOM 8531 O LEU E 116 39.114 -8.782 73.636 1.00 88.60 O +ATOM 8532 CB LEU E 116 37.078 -9.775 71.632 1.00 71.67 C +ATOM 8533 CG LEU E 116 35.907 -9.710 70.682 1.00 99.58 C +ATOM 8534 CD1 LEU E 116 36.001 -8.510 69.734 1.00115.58 C +ATOM 8535 CD2 LEU E 116 35.879 -11.021 69.907 1.00130.25 C +ATOM 8536 N THR E 117 37.858 -10.124 74.946 1.00 86.88 N +ATOM 8537 CA THR E 117 38.936 -10.469 75.849 1.00108.76 C +ATOM 8538 C THR E 117 40.077 -11.102 75.059 1.00115.40 C +ATOM 8539 O THR E 117 39.834 -11.968 74.217 1.00117.96 O +ATOM 8540 CB THR E 117 38.487 -11.494 76.908 1.00134.39 C +ATOM 8541 OG1 THR E 117 37.331 -10.998 77.595 1.00169.95 O +ATOM 8542 CG2 THR E 117 39.592 -11.714 77.924 1.00135.28 C +ATOM 8543 N ALA E 118 41.308 -10.662 75.332 1.00104.49 N +ATOM 8544 CA ALA E 118 42.449 -10.958 74.459 1.00 86.84 C +ATOM 8545 C ALA E 118 43.471 -11.716 75.177 1.00 82.35 C +ATOM 8546 O ALA E 118 43.779 -11.423 76.353 1.00 82.14 O +ATOM 8547 CB ALA E 118 43.073 -9.684 73.924 1.00119.73 C +ATOM 8548 N ALA E 119 44.025 -12.687 74.467 1.00 97.73 N +ATOM 8549 CA ALA E 119 44.953 -13.658 75.058 1.00107.61 C +ATOM 8550 C ALA E 119 46.400 -13.150 75.055 1.00 93.84 C +ATOM 8551 O ALA E 119 46.749 -12.289 74.243 1.00 63.12 O +ATOM 8552 CB ALA E 119 44.879 -14.956 74.300 1.00 94.62 C +ATOM 8553 N ASN E 120 47.212 -13.637 75.998 1.00 79.90 N +ATOM 8554 CA ASN E 120 48.624 -13.278 76.016 1.00 89.43 C +ATOM 8555 C ASN E 120 49.509 -14.325 75.371 1.00 84.81 C +ATOM 8556 O ASN E 120 50.400 -14.019 74.586 1.00 96.79 O +ATOM 8557 CB ASN E 120 49.146 -13.021 77.423 1.00 93.72 C +ATOM 8558 CG ASN E 120 50.603 -12.554 77.412 1.00118.61 C +ATOM 8559 OD1 ASN E 120 51.392 -12.998 78.237 1.00145.81 O +ATOM 8560 ND2 ASN E 120 50.986 -11.710 76.421 1.00113.03 N +ATOM 8561 N ILE E 121 49.303 -15.566 75.752 1.00 69.76 N +ATOM 8562 CA ILE E 121 49.946 -16.638 75.058 1.00 76.82 C +ATOM 8563 C ILE E 121 48.890 -17.360 74.232 1.00 83.65 C +ATOM 8564 O ILE E 121 47.761 -17.548 74.644 1.00 94.07 O +ATOM 8565 CB ILE E 121 50.664 -17.597 76.032 1.00 97.37 C +ATOM 8566 CG1 ILE E 121 49.675 -18.493 76.809 1.00124.49 C +ATOM 8567 CG2 ILE E 121 51.558 -16.815 76.988 1.00 93.13 C +ATOM 8568 CD1 ILE E 121 49.725 -19.959 76.414 1.00134.49 C +ATOM 8569 N MET E 122 49.270 -17.781 73.056 1.00 91.11 N +ATOM 8570 CA MET E 122 48.468 -18.732 72.387 1.00103.72 C +ATOM 8571 C MET E 122 49.273 -20.024 72.211 1.00 86.42 C +ATOM 8572 O MET E 122 50.455 -19.989 71.891 1.00 83.20 O +ATOM 8573 CB MET E 122 47.935 -18.104 71.076 1.00150.70 C +ATOM 8574 CG MET E 122 48.966 -17.579 70.080 1.00132.10 C +ATOM 8575 SD MET E 122 48.310 -17.706 68.386 1.00 98.91 S +ATOM 8576 CE MET E 122 49.722 -18.244 67.476 1.00 90.58 C +ATOM 8577 N VAL E 123 48.589 -21.157 72.299 1.00 59.75 N +ATOM 8578 CA VAL E 123 49.216 -22.434 72.004 1.00 53.69 C +ATOM 8579 C VAL E 123 48.645 -23.165 70.804 1.00 49.84 C +ATOM 8580 O VAL E 123 47.433 -23.311 70.654 1.00 50.76 O +ATOM 8581 CB VAL E 123 49.066 -23.351 73.189 1.00 70.19 C +ATOM 8582 CG1 VAL E 123 47.670 -23.235 73.795 1.00 65.36 C +ATOM 8583 CG2 VAL E 123 49.404 -24.805 72.819 1.00 85.34 C +ATOM 8584 N GLU E 124 49.520 -23.588 69.904 1.00 70.44 N +ATOM 8585 CA GLU E 124 49.099 -24.354 68.730 1.00108.42 C +ATOM 8586 C GLU E 124 49.980 -25.566 68.591 1.00108.49 C +ATOM 8587 O GLU E 124 50.976 -25.698 69.267 1.00 64.64 O +ATOM 8588 CB GLU E 124 49.142 -23.545 67.414 1.00135.84 C +ATOM 8589 CG GLU E 124 50.183 -22.440 67.342 1.00137.51 C +ATOM 8590 CD GLU E 124 49.878 -21.432 66.248 1.00154.41 C +ATOM 8591 OE1 GLU E 124 48.687 -21.157 65.986 1.00122.89 O +ATOM 8592 OE2 GLU E 124 50.844 -20.985 65.604 1.00203.97 O +ATOM 8593 N GLY E 125 49.564 -26.475 67.719 1.00139.19 N +ATOM 8594 CA GLY E 125 50.238 -27.751 67.573 1.00111.02 C +ATOM 8595 C GLY E 125 49.703 -28.554 66.407 1.00 76.08 C +ATOM 8596 O GLY E 125 49.045 -28.014 65.518 1.00 63.07 O +ATOM 8597 N SER E 126 49.981 -29.844 66.420 1.00 59.05 N +ATOM 8598 CA SER E 126 49.650 -30.663 65.285 1.00 71.19 C +ATOM 8599 C SER E 126 49.651 -32.105 65.690 1.00 96.14 C +ATOM 8600 O SER E 126 50.395 -32.499 66.598 1.00123.90 O +ATOM 8601 CB SER E 126 50.677 -30.503 64.161 1.00 66.93 C +ATOM 8602 OG SER E 126 51.238 -29.202 64.121 1.00 57.95 O +ATOM 8603 N ILE E 127 48.795 -32.905 65.051 1.00 88.70 N +ATOM 8604 CA ILE E 127 48.900 -34.343 65.201 1.00 91.00 C +ATOM 8605 C ILE E 127 50.016 -34.743 64.270 1.00 98.57 C +ATOM 8606 O ILE E 127 49.816 -34.829 63.075 1.00 93.91 O +ATOM 8607 CB ILE E 127 47.590 -35.109 64.895 1.00 66.73 C +ATOM 8608 CG1 ILE E 127 46.536 -34.816 65.990 1.00 55.26 C +ATOM 8609 CG2 ILE E 127 47.850 -36.608 64.849 1.00 66.66 C +ATOM 8610 CD1 ILE E 127 45.123 -34.881 65.474 1.00 59.69 C +ATOM 8611 N ILE E 128 51.190 -35.003 64.852 1.00 97.99 N +ATOM 8612 CA ILE E 128 52.388 -35.406 64.110 1.00115.76 C +ATOM 8613 C ILE E 128 52.469 -36.926 64.102 1.00 91.51 C +ATOM 8614 O ILE E 128 52.646 -37.580 65.147 1.00170.24 O +ATOM 8615 CB ILE E 128 53.653 -34.785 64.738 1.00169.87 C +ATOM 8616 CG1 ILE E 128 53.744 -35.112 66.231 1.00211.05 C +ATOM 8617 CG2 ILE E 128 53.598 -33.270 64.642 1.00183.85 C +ATOM 8618 CD1 ILE E 128 55.168 -35.078 66.759 1.00239.91 C +ATOM 8619 N GLY E 129 51.995 -37.490 63.009 1.00 93.63 N +ATOM 8620 CA GLY E 129 52.088 -38.929 62.838 1.00135.18 C +ATOM 8621 C GLY E 129 51.051 -39.885 63.466 1.00142.09 C +ATOM 8622 O GLY E 129 50.640 -39.770 64.633 1.00117.49 O +ATOM 8623 N TYR E 130 50.648 -40.855 62.654 1.00123.26 N +ATOM 8624 CA TYR E 130 50.000 -42.059 63.125 1.00106.79 C +ATOM 8625 C TYR E 130 50.611 -43.177 62.294 1.00 97.70 C +ATOM 8626 O TYR E 130 50.345 -43.263 61.103 1.00114.90 O +ATOM 8627 CB TYR E 130 48.480 -41.951 62.912 1.00 97.15 C +ATOM 8628 CG TYR E 130 47.669 -43.188 63.227 1.00 95.76 C +ATOM 8629 CD1 TYR E 130 47.759 -44.330 62.429 1.00 87.26 C +ATOM 8630 CD2 TYR E 130 46.744 -43.187 64.279 1.00105.06 C +ATOM 8631 CE1 TYR E 130 46.994 -45.455 62.708 1.00110.13 C +ATOM 8632 CE2 TYR E 130 45.956 -44.300 64.557 1.00131.44 C +ATOM 8633 CZ TYR E 130 46.081 -45.432 63.769 1.00131.80 C +ATOM 8634 OH TYR E 130 45.368 -46.558 64.123 1.00110.03 O +ATOM 8635 N GLU E 131 51.466 -43.978 62.900 1.00 76.90 N +ATOM 8636 CA GLU E 131 51.913 -45.194 62.243 1.00 93.26 C +ATOM 8637 C GLU E 131 51.031 -46.354 62.724 1.00115.16 C +ATOM 8638 O GLU E 131 50.539 -46.355 63.859 1.00 64.15 O +ATOM 8639 CB GLU E 131 53.418 -45.456 62.425 1.00133.74 C +ATOM 8640 CG GLU E 131 54.279 -44.664 61.385 1.00155.65 C +ATOM 8641 CD GLU E 131 53.672 -44.449 60.044 1.00150.84 C +ATOM 8642 OE1 GLU E 131 53.935 -45.302 59.235 1.00168.28 O +ATOM 8643 OE2 GLU E 131 53.222 -43.328 59.726 1.00140.77 O +ATOM 8644 N SER E 132 50.786 -47.318 61.831 1.00149.33 N +ATOM 8645 CA SER E 132 49.835 -48.398 62.109 1.00138.13 C +ATOM 8646 C SER E 132 50.511 -49.783 62.123 1.00132.51 C +ATOM 8647 O SER E 132 51.384 -50.065 61.295 1.00106.49 O +ATOM 8648 CB SER E 132 48.699 -48.366 61.093 1.00123.04 C +ATOM 8649 OG SER E 132 48.737 -49.506 60.252 1.00165.17 O +ATOM 8650 N ASN E 133 50.081 -50.633 63.060 1.00111.67 N +ATOM 8651 CA ASN E 133 50.736 -51.916 63.337 1.00 96.90 C +ATOM 8652 C ASN E 133 52.223 -51.748 63.515 1.00116.17 C +ATOM 8653 O ASN E 133 53.033 -52.342 62.776 1.00131.04 O +ATOM 8654 CB ASN E 133 50.465 -52.941 62.230 1.00 89.39 C +ATOM 8655 CG ASN E 133 49.001 -53.278 62.091 1.00 95.63 C +ATOM 8656 OD1 ASN E 133 48.207 -53.159 63.043 1.00 90.66 O +ATOM 8657 ND2 ASN E 133 48.608 -53.634 60.877 1.00121.76 N +ATOM 8658 N VAL E 134 52.580 -50.882 64.456 1.00115.99 N +ATOM 8659 CA VAL E 134 53.982 -50.577 64.721 1.00143.65 C +ATOM 8660 C VAL E 134 54.584 -51.835 65.316 1.00142.43 C +ATOM 8661 O VAL E 134 55.750 -52.172 65.080 1.00 83.34 O +ATOM 8662 CB VAL E 134 54.113 -49.369 65.678 1.00138.58 C +ATOM 8663 CG1 VAL E 134 55.578 -49.019 65.919 1.00135.29 C +ATOM 8664 CG2 VAL E 134 53.387 -48.152 65.101 1.00185.21 C +ATOM 8665 N LYS E 135 53.752 -52.541 66.080 1.00178.10 N +ATOM 8666 CA LYS E 135 54.057 -53.915 66.468 1.00182.29 C +ATOM 8667 C LYS E 135 52.824 -54.803 66.345 1.00153.76 C +ATOM 8668 O LYS E 135 51.683 -54.332 66.380 1.00 91.76 O +ATOM 8669 CB LYS E 135 54.582 -53.975 67.908 1.00219.55 C +ATOM 8670 CG LYS E 135 55.891 -53.228 68.125 1.00227.92 C +ATOM 8671 CD LYS E 135 56.283 -53.241 69.594 1.00211.05 C +ATOM 8672 CE LYS E 135 57.570 -52.483 69.838 1.00191.46 C +ATOM 8673 NZ LYS E 135 58.182 -52.911 71.118 1.00194.18 N +ATOM 8674 N SER E 136 53.076 -56.101 66.244 1.00162.00 N +ATOM 8675 CA SER E 136 52.008 -57.072 66.137 1.00140.40 C +ATOM 8676 C SER E 136 52.518 -58.476 66.411 1.00145.34 C +ATOM 8677 O SER E 136 53.713 -58.758 66.309 1.00 91.55 O +ATOM 8678 CB SER E 136 51.361 -57.015 64.759 1.00131.86 C +ATOM 8679 OG SER E 136 51.396 -58.276 64.122 1.00147.72 O +ATOM 8680 N GLY E 137 51.597 -59.350 66.798 1.00181.36 N +ATOM 8681 CA GLY E 137 51.938 -60.743 67.072 1.00197.57 C +ATOM 8682 C GLY E 137 50.721 -61.648 67.156 1.00175.92 C +ATOM 8683 O GLY E 137 49.589 -61.179 67.182 1.00 91.06 O +ATOM 8684 N GLY E 138 50.970 -62.949 67.251 1.00176.03 N +ATOM 8685 CA GLY E 138 49.899 -63.908 67.437 1.00172.64 C +ATOM 8686 C GLY E 138 50.394 -65.256 67.911 1.00176.00 C +ATOM 8687 O GLY E 138 51.495 -65.684 67.562 1.00158.61 O +ATOM 8688 N VAL E 139 49.587 -65.909 68.743 1.00187.34 N +ATOM 8689 CA VAL E 139 49.882 -67.261 69.216 1.00168.50 C +ATOM 8690 C VAL E 139 48.614 -68.116 69.196 1.00189.01 C +ATOM 8691 O VAL E 139 47.587 -67.744 69.773 1.00201.50 O +ATOM 8692 CB VAL E 139 50.446 -67.257 70.644 1.00134.97 C +ATOM 8693 CG1 VAL E 139 50.619 -68.682 71.134 1.00132.60 C +ATOM 8694 CG2 VAL E 139 51.770 -66.505 70.699 1.00118.90 C +ATOM 8695 N GLY E 140 48.688 -69.262 68.523 1.00184.99 N +ATOM 8696 CA GLY E 140 47.534 -70.147 68.387 1.00167.42 C +ATOM 8697 C GLY E 140 47.923 -71.612 68.263 1.00159.77 C +ATOM 8698 O GLY E 140 48.938 -71.959 67.653 1.00134.22 O +ATOM 8699 N ALA E 141 47.102 -72.479 68.843 1.00171.76 N +ATOM 8700 CA ALA E 141 47.327 -73.916 68.751 1.00169.69 C +ATOM 8701 C ALA E 141 46.015 -74.684 68.641 1.00189.77 C +ATOM 8702 O ALA E 141 45.006 -74.336 69.266 1.00157.44 O +ATOM 8703 CB ALA E 141 48.135 -74.406 69.939 1.00153.39 C +ATOM 8704 N ARG E 142 46.026 -75.700 67.791 1.00197.08 N +ATOM 8705 CA ARG E 142 44.906 -76.607 67.701 1.00184.77 C +ATOM 8706 C ARG E 142 45.433 -78.022 67.838 1.00188.51 C +ATOM 8707 O ARG E 142 46.536 -78.327 67.388 1.00134.01 O +ATOM 8708 CB ARG E 142 44.133 -76.419 66.386 1.00164.05 C +ATOM 8709 CG ARG E 142 42.894 -77.299 66.297 1.00147.25 C +ATOM 8710 CD ARG E 142 41.678 -76.583 65.741 1.00147.77 C +ATOM 8711 NE ARG E 142 41.458 -76.762 64.319 1.00173.48 N +ATOM 8712 CZ ARG E 142 40.671 -75.972 63.591 1.00182.08 C +ATOM 8713 NH1 ARG E 142 40.199 -74.823 64.084 1.00199.32 N +ATOM 8714 NH2 ARG E 142 40.442 -76.285 62.329 1.00157.47 N +ATOM 8715 N TYR E 143 44.647 -78.867 68.496 1.00218.79 N +ATOM 8716 CA TYR E 143 45.054 -80.224 68.825 1.00223.04 C +ATOM 8717 C TYR E 143 43.967 -81.221 68.403 1.00199.26 C +ATOM 8718 O TYR E 143 43.153 -81.668 69.213 1.00191.18 O +ATOM 8719 CB TYR E 143 45.348 -80.332 70.327 1.00224.13 C +ATOM 8720 CG TYR E 143 45.905 -81.668 70.713 1.00231.02 C +ATOM 8721 CD1 TYR E 143 47.178 -82.045 70.315 1.00215.44 C +ATOM 8722 CD2 TYR E 143 45.128 -82.589 71.400 1.00243.79 C +ATOM 8723 CE1 TYR E 143 47.679 -83.297 70.615 1.00236.61 C +ATOM 8724 CE2 TYR E 143 45.619 -83.843 71.715 1.00248.76 C +ATOM 8725 CZ TYR E 143 46.895 -84.194 71.315 1.00255.62 C +ATOM 8726 OH TYR E 143 47.391 -85.443 71.614 1.00269.34 O +ATOM 8727 N GLY E 145 41.429 -81.556 67.534 1.00108.61 N +ATOM 8728 CA GLY E 145 40.040 -81.121 67.541 1.00142.88 C +ATOM 8729 C GLY E 145 39.749 -79.802 68.260 1.00198.89 C +ATOM 8730 O GLY E 145 38.775 -79.128 67.913 1.00200.84 O +ATOM 8731 N ILE E 146 40.557 -79.439 69.265 1.00227.77 N +ATOM 8732 CA ILE E 146 40.291 -78.270 70.139 1.00195.52 C +ATOM 8733 C ILE E 146 41.378 -77.207 69.921 1.00208.87 C +ATOM 8734 O ILE E 146 42.553 -77.543 69.794 1.00149.57 O +ATOM 8735 CB ILE E 146 40.257 -78.657 71.643 1.00145.90 C +ATOM 8736 CG1 ILE E 146 39.562 -80.015 71.833 1.00139.51 C +ATOM 8737 CG2 ILE E 146 39.557 -77.578 72.461 1.00114.07 C +ATOM 8738 CD1 ILE E 146 40.511 -81.196 71.921 1.00114.73 C +ATOM 8739 N GLY E 147 40.991 -75.933 69.828 1.00229.15 N +ATOM 8740 CA GLY E 147 41.958 -74.881 69.492 1.00211.16 C +ATOM 8741 C GLY E 147 41.671 -73.502 70.049 1.00215.11 C +ATOM 8742 O GLY E 147 40.526 -73.156 70.343 1.00224.95 O +ATOM 8743 N ALA E 148 42.725 -72.708 70.193 1.00203.01 N +ATOM 8744 CA ALA E 148 42.579 -71.306 70.561 1.00208.30 C +ATOM 8745 C ALA E 148 43.678 -70.470 69.910 1.00200.08 C +ATOM 8746 O ALA E 148 44.657 -71.014 69.398 1.00189.05 O +ATOM 8747 CB ALA E 148 42.583 -71.149 72.081 1.00181.80 C +ATOM 8748 N ASP E 149 43.494 -69.151 69.917 1.00178.20 N +ATOM 8749 CA ASP E 149 44.502 -68.232 69.401 1.00151.22 C +ATOM 8750 C ASP E 149 44.256 -66.814 69.886 1.00168.20 C +ATOM 8751 O ASP E 149 43.111 -66.427 70.078 1.00128.61 O +ATOM 8752 CB ASP E 149 44.532 -68.240 67.873 1.00132.79 C +ATOM 8753 CG ASP E 149 45.711 -67.401 67.321 1.00125.16 C +ATOM 8754 OD1 ASP E 149 46.461 -66.757 68.116 1.00173.24 O +ATOM 8755 OD2 ASP E 149 45.855 -67.273 66.088 1.00107.30 O +ATOM 8756 N THR E 150 45.330 -66.064 70.130 1.00191.49 N +ATOM 8757 CA THR E 150 45.208 -64.616 70.257 1.00172.74 C +ATOM 8758 C THR E 150 46.092 -63.930 69.222 1.00197.70 C +ATOM 8759 O THR E 150 47.070 -64.504 68.730 1.00218.33 O +ATOM 8760 CB THR E 150 45.598 -64.105 71.652 1.00142.02 C +ATOM 8761 OG1 THR E 150 46.958 -64.473 71.935 1.00165.17 O +ATOM 8762 CG2 THR E 150 44.681 -64.670 72.705 1.00119.18 C +ATOM 8763 N GLN E 151 45.695 -62.724 68.856 1.00200.45 N +ATOM 8764 CA GLN E 151 46.474 -61.897 67.967 1.00164.91 C +ATOM 8765 C GLN E 151 46.430 -60.488 68.525 1.00164.03 C +ATOM 8766 O GLN E 151 45.412 -60.061 69.065 1.00188.61 O +ATOM 8767 CB GLN E 151 45.876 -61.956 66.562 1.00168.42 C +ATOM 8768 CG GLN E 151 46.138 -63.282 65.831 1.00157.94 C +ATOM 8769 CD GLN E 151 45.223 -63.491 64.591 1.00172.25 C +ATOM 8770 OE1 GLN E 151 45.412 -64.307 63.591 1.00176.75 O +ATOM 8771 NE2 GLN E 151 44.176 -62.759 64.667 1.00177.70 N +ATOM 8772 N TYR E 152 47.535 -59.770 68.443 1.00139.26 N +ATOM 8773 CA TYR E 152 47.537 -58.386 68.882 1.00159.04 C +ATOM 8774 C TYR E 152 48.245 -57.472 67.899 1.00192.13 C +ATOM 8775 O TYR E 152 49.188 -57.886 67.228 1.00164.62 O +ATOM 8776 CB TYR E 152 48.146 -58.274 70.278 1.00139.19 C +ATOM 8777 CG TYR E 152 49.556 -57.718 70.368 1.00149.29 C +ATOM 8778 CD1 TYR E 152 50.643 -58.395 69.821 1.00162.52 C +ATOM 8779 CD2 TYR E 152 49.814 -56.574 71.104 1.00138.58 C +ATOM 8780 CE1 TYR E 152 51.940 -57.888 69.925 1.00139.47 C +ATOM 8781 CE2 TYR E 152 51.106 -56.078 71.241 1.00133.85 C +ATOM 8782 CZ TYR E 152 52.163 -56.729 70.633 1.00128.66 C +ATOM 8783 OH TYR E 152 53.433 -56.231 70.766 1.00107.76 O +ATOM 8784 N GLN E 153 47.745 -56.241 67.781 1.00206.70 N +ATOM 8785 CA GLN E 153 48.437 -55.211 67.018 1.00189.15 C +ATOM 8786 C GLN E 153 48.444 -53.906 67.804 1.00159.23 C +ATOM 8787 O GLN E 153 47.586 -53.680 68.665 1.00 93.07 O +ATOM 8788 CB GLN E 153 47.757 -54.999 65.659 1.00207.61 C +ATOM 8789 CG GLN E 153 47.857 -56.201 64.728 1.00202.97 C +ATOM 8790 CD GLN E 153 46.801 -57.291 64.976 1.00177.86 C +ATOM 8791 OE1 GLN E 153 45.920 -57.158 65.837 1.00153.35 O +ATOM 8792 NE2 GLN E 153 46.854 -58.348 64.172 1.00131.20 N +ATOM 8793 N LEU E 154 49.463 -53.080 67.568 1.00166.07 N +ATOM 8794 CA LEU E 154 49.486 -51.748 68.185 1.00141.97 C +ATOM 8795 C LEU E 154 50.073 -50.672 67.266 1.00144.85 C +ATOM 8796 O LEU E 154 51.022 -50.919 66.497 1.00 87.25 O +ATOM 8797 CB LEU E 154 50.222 -51.760 69.527 1.00107.43 C +ATOM 8798 CG LEU E 154 51.744 -51.919 69.428 1.00166.21 C +ATOM 8799 CD1 LEU E 154 52.449 -50.572 69.449 1.00167.10 C +ATOM 8800 CD2 LEU E 154 52.238 -52.811 70.555 1.00216.43 C +ATOM 8801 N ASP E 155 49.515 -49.473 67.428 1.00136.98 N +ATOM 8802 CA ASP E 155 49.718 -48.346 66.527 1.00106.40 C +ATOM 8803 C ASP E 155 50.239 -47.185 67.319 1.00 76.21 C +ATOM 8804 O ASP E 155 50.130 -47.177 68.566 1.00 93.19 O +ATOM 8805 CB ASP E 155 48.384 -47.944 65.897 1.00134.80 C +ATOM 8806 CG ASP E 155 47.604 -49.137 65.343 1.00161.60 C +ATOM 8807 OD1 ASP E 155 46.927 -49.836 66.137 1.00122.95 O +ATOM 8808 OD2 ASP E 155 47.644 -49.353 64.108 1.00162.39 O +ATOM 8809 N GLN E 156 50.838 -46.212 66.642 1.00 77.77 N +ATOM 8810 CA GLN E 156 51.420 -45.042 67.358 1.00137.29 C +ATOM 8811 C GLN E 156 50.762 -43.729 66.952 1.00140.67 C +ATOM 8812 O GLN E 156 50.118 -43.657 65.917 1.00164.41 O +ATOM 8813 CB GLN E 156 52.918 -44.927 67.098 1.00147.27 C +ATOM 8814 CG GLN E 156 53.638 -43.936 67.995 1.00131.38 C +ATOM 8815 CD GLN E 156 55.131 -44.187 68.042 1.00140.39 C +ATOM 8816 OE1 GLN E 156 55.679 -44.996 67.271 1.00127.40 O +ATOM 8817 NE2 GLN E 156 55.810 -43.489 68.948 1.00152.42 N +ATOM 8818 N ILE E 157 50.813 -42.742 67.841 1.00109.54 N +ATOM 8819 CA ILE E 157 50.214 -41.452 67.569 1.00111.49 C +ATOM 8820 C ILE E 157 51.023 -40.426 68.350 1.00137.71 C +ATOM 8821 O ILE E 157 51.403 -40.661 69.510 1.00243.02 O +ATOM 8822 CB ILE E 157 48.708 -41.414 67.950 1.00102.59 C +ATOM 8823 CG1 ILE E 157 47.988 -40.330 67.168 1.00117.59 C +ATOM 8824 CG2 ILE E 157 48.521 -41.169 69.445 1.00114.96 C +ATOM 8825 CD1 ILE E 157 46.477 -40.330 67.342 1.00136.25 C +ATOM 8826 N ALA E 158 51.338 -39.305 67.722 1.00148.87 N +ATOM 8827 CA ALA E 158 52.153 -38.300 68.397 1.00128.27 C +ATOM 8828 C ALA E 158 51.545 -36.929 68.202 1.00112.00 C +ATOM 8829 O ALA E 158 50.840 -36.670 67.222 1.00 69.52 O +ATOM 8830 CB ALA E 158 53.596 -38.339 67.905 1.00 99.28 C +ATOM 8831 N VAL E 159 51.789 -36.068 69.180 1.00 96.84 N +ATOM 8832 CA VAL E 159 51.185 -34.754 69.188 1.00 95.12 C +ATOM 8833 C VAL E 159 52.213 -33.709 69.582 1.00 91.80 C +ATOM 8834 O VAL E 159 52.894 -33.849 70.608 1.00122.21 O +ATOM 8835 CB VAL E 159 49.967 -34.718 70.145 1.00 99.48 C +ATOM 8836 CG1 VAL E 159 49.628 -33.294 70.555 1.00 96.17 C +ATOM 8837 CG2 VAL E 159 48.759 -35.369 69.484 1.00105.43 C +ATOM 8838 N ASN E 160 52.321 -32.668 68.764 1.00 72.56 N +ATOM 8839 CA ASN E 160 53.072 -31.482 69.132 1.00 70.49 C +ATOM 8840 C ASN E 160 52.121 -30.445 69.717 1.00 76.63 C +ATOM 8841 O ASN E 160 51.036 -30.177 69.149 1.00 94.68 O +ATOM 8842 CB ASN E 160 53.758 -30.920 67.898 1.00 63.74 C +ATOM 8843 CG ASN E 160 54.533 -29.620 68.175 1.00 65.54 C +ATOM 8844 OD1 ASN E 160 53.998 -28.663 68.749 1.00 54.83 O +ATOM 8845 ND2 ASN E 160 55.731 -29.521 67.601 1.00 57.24 N +ATOM 8846 N LEU E 161 52.492 -29.889 70.865 1.00 53.46 N +ATOM 8847 CA LEU E 161 51.880 -28.672 71.311 1.00 53.75 C +ATOM 8848 C LEU E 161 52.952 -27.664 71.503 1.00 50.18 C +ATOM 8849 O LEU E 161 54.022 -27.979 72.020 1.00 78.53 O +ATOM 8850 CB LEU E 161 51.071 -28.898 72.600 1.00 61.64 C +ATOM 8851 CG LEU E 161 49.843 -29.792 72.477 1.00 71.65 C +ATOM 8852 CD1 LEU E 161 49.255 -30.092 73.853 1.00 96.78 C +ATOM 8853 CD2 LEU E 161 48.796 -29.135 71.590 1.00 64.71 C +ATOM 8854 N ARG E 162 52.625 -26.399 71.304 1.00 64.76 N +ATOM 8855 CA ARG E 162 53.609 -25.355 71.598 1.00 94.82 C +ATOM 8856 C ARG E 162 53.034 -23.967 71.971 1.00 68.01 C +ATOM 8857 O ARG E 162 52.137 -23.470 71.326 1.00 85.18 O +ATOM 8858 CB ARG E 162 54.590 -25.259 70.424 1.00108.38 C +ATOM 8859 CG ARG E 162 54.000 -24.845 69.086 1.00117.85 C +ATOM 8860 CD ARG E 162 55.117 -24.411 68.138 1.00123.03 C +ATOM 8861 NE ARG E 162 54.651 -23.793 66.886 1.00 92.98 N +ATOM 8862 CZ ARG E 162 54.246 -24.460 65.819 1.00 75.96 C +ATOM 8863 NH1 ARG E 162 54.152 -25.787 65.864 1.00 95.77 N +ATOM 8864 NH2 ARG E 162 53.898 -23.798 64.730 1.00 61.05 N +ATOM 8865 N VAL E 163 53.611 -23.366 73.008 1.00 55.20 N +ATOM 8866 CA VAL E 163 53.216 -22.062 73.493 1.00 55.23 C +ATOM 8867 C VAL E 163 53.972 -21.038 72.725 1.00 54.41 C +ATOM 8868 O VAL E 163 55.201 -20.972 72.811 1.00 63.98 O +ATOM 8869 CB VAL E 163 53.584 -21.861 74.980 1.00 79.68 C +ATOM 8870 CG1 VAL E 163 53.198 -20.460 75.439 1.00 80.28 C +ATOM 8871 CG2 VAL E 163 52.917 -22.942 75.850 1.00108.22 C +ATOM 8872 N VAL E 164 53.216 -20.146 72.102 1.00 67.44 N +ATOM 8873 CA VAL E 164 53.752 -19.001 71.372 1.00 80.39 C +ATOM 8874 C VAL E 164 53.388 -17.671 72.024 1.00 64.78 C +ATOM 8875 O VAL E 164 52.292 -17.510 72.530 1.00 45.60 O +ATOM 8876 CB VAL E 164 53.171 -18.917 69.976 1.00 75.09 C +ATOM 8877 CG1 VAL E 164 53.756 -17.718 69.263 1.00 92.91 C +ATOM 8878 CG2 VAL E 164 53.507 -20.177 69.236 1.00 88.21 C +ATOM 8879 N ASN E 165 54.400 -16.814 72.181 1.00 76.95 N +ATOM 8880 CA ASN E 165 54.234 -15.548 72.885 1.00 80.99 C +ATOM 8881 C ASN E 165 53.709 -14.513 71.899 1.00 82.66 C +ATOM 8882 O ASN E 165 54.380 -14.223 70.905 1.00 90.20 O +ATOM 8883 CB ASN E 165 55.551 -15.056 73.530 1.00 60.25 C +ATOM 8884 CG ASN E 165 55.316 -13.888 74.456 1.00 64.44 C +ATOM 8885 OD1 ASN E 165 54.156 -13.470 74.654 1.00 85.34 O +ATOM 8886 ND2 ASN E 165 56.371 -13.194 74.792 1.00 76.96 N +ATOM 8887 N VAL E 166 52.532 -13.962 72.195 1.00 68.69 N +ATOM 8888 CA VAL E 166 51.836 -13.077 71.269 1.00 62.07 C +ATOM 8889 C VAL E 166 52.635 -11.855 71.096 1.00 50.59 C +ATOM 8890 O VAL E 166 52.769 -11.339 69.998 1.00 44.66 O +ATOM 8891 CB VAL E 166 50.438 -12.705 71.806 1.00 79.32 C +ATOM 8892 CG1 VAL E 166 49.990 -11.353 71.278 1.00 69.83 C +ATOM 8893 CG2 VAL E 166 49.413 -13.831 71.485 1.00 82.13 C +ATOM 8894 N SER E 167 53.236 -11.428 72.188 1.00 67.05 N +ATOM 8895 CA SER E 167 53.969 -10.169 72.197 1.00 94.81 C +ATOM 8896 C SER E 167 55.262 -10.180 71.340 1.00 73.96 C +ATOM 8897 O SER E 167 55.834 -9.109 71.099 1.00 64.21 O +ATOM 8898 CB SER E 167 54.261 -9.758 73.650 1.00103.65 C +ATOM 8899 OG SER E 167 53.110 -9.960 74.462 1.00111.88 O +ATOM 8900 N THR E 168 55.721 -11.363 70.922 1.00 52.36 N +ATOM 8901 CA THR E 168 56.997 -11.471 70.238 1.00 60.69 C +ATOM 8902 C THR E 168 56.997 -12.451 69.075 1.00 59.40 C +ATOM 8903 O THR E 168 57.726 -12.296 68.083 1.00 61.33 O +ATOM 8904 CB THR E 168 58.151 -11.874 71.197 1.00 63.17 C +ATOM 8905 OG1 THR E 168 57.789 -13.041 71.934 1.00 78.39 O +ATOM 8906 CG2 THR E 168 58.506 -10.732 72.172 1.00 62.54 C +ATOM 8907 N GLY E 169 56.259 -13.514 69.233 1.00 59.98 N +ATOM 8908 CA GLY E 169 56.348 -14.563 68.265 1.00 76.82 C +ATOM 8909 C GLY E 169 57.403 -15.581 68.624 1.00100.78 C +ATOM 8910 O GLY E 169 57.388 -16.696 68.070 1.00211.70 O +ATOM 8911 N GLU E 170 58.223 -15.296 69.637 1.00 90.75 N +ATOM 8912 CA GLU E 170 59.000 -16.359 70.308 1.00105.79 C +ATOM 8913 C GLU E 170 58.090 -17.528 70.728 1.00 86.59 C +ATOM 8914 O GLU E 170 57.099 -17.342 71.387 1.00 89.59 O +ATOM 8915 CB GLU E 170 59.748 -15.842 71.557 1.00105.25 C +ATOM 8916 CG GLU E 170 60.962 -14.975 71.229 1.00111.11 C +ATOM 8917 CD GLU E 170 61.184 -13.832 72.198 1.00112.47 C +ATOM 8918 OE1 GLU E 170 60.269 -13.546 73.015 1.00114.89 O +ATOM 8919 OE2 GLU E 170 62.224 -13.142 72.076 1.00133.22 O +ATOM 8920 N ILE E 171 58.392 -18.725 70.271 1.00 69.31 N +ATOM 8921 CA ILE E 171 57.830 -19.876 70.874 1.00 74.74 C +ATOM 8922 C ILE E 171 58.415 -20.024 72.296 1.00127.34 C +ATOM 8923 O ILE E 171 59.646 -20.049 72.485 1.00220.70 O +ATOM 8924 CB ILE E 171 58.156 -21.095 70.040 1.00 73.23 C +ATOM 8925 CG1 ILE E 171 57.374 -21.020 68.756 1.00 68.32 C +ATOM 8926 CG2 ILE E 171 57.834 -22.360 70.833 1.00102.62 C +ATOM 8927 CD1 ILE E 171 57.899 -21.984 67.712 1.00102.01 C +ATOM 8928 N LEU E 172 57.549 -20.127 73.300 1.00146.17 N +ATOM 8929 CA LEU E 172 58.008 -20.199 74.689 1.00153.10 C +ATOM 8930 C LEU E 172 58.148 -21.642 75.205 1.00133.16 C +ATOM 8931 O LEU E 172 58.771 -21.920 76.259 1.00171.17 O +ATOM 8932 CB LEU E 172 57.073 -19.422 75.608 1.00158.85 C +ATOM 8933 CG LEU E 172 57.132 -17.883 75.420 1.00185.41 C +ATOM 8934 CD1 LEU E 172 56.322 -17.034 76.417 1.00168.79 C +ATOM 8935 CD2 LEU E 172 58.558 -17.359 75.298 1.00204.83 C +ATOM 8936 N SER E 173 57.591 -22.566 74.448 1.00 88.52 N +ATOM 8937 CA SER E 173 57.710 -23.965 74.772 1.00112.46 C +ATOM 8938 C SER E 173 57.214 -24.835 73.614 1.00114.62 C +ATOM 8939 O SER E 173 56.117 -24.633 73.105 1.00188.53 O +ATOM 8940 CB SER E 173 56.877 -24.266 76.017 1.00151.94 C +ATOM 8941 OG SER E 173 56.667 -25.663 76.174 1.00241.01 O +ATOM 8942 N SER E 174 57.981 -25.853 73.252 1.00 96.39 N +ATOM 8943 CA SER E 174 57.482 -26.905 72.383 1.00 87.75 C +ATOM 8944 C SER E 174 57.564 -28.245 73.115 1.00 98.22 C +ATOM 8945 O SER E 174 58.577 -28.557 73.746 1.00152.94 O +ATOM 8946 CB SER E 174 58.294 -26.948 71.075 1.00 76.38 C +ATOM 8947 OG SER E 174 57.704 -27.787 70.094 1.00 81.40 O +ATOM 8948 N VAL E 175 56.522 -29.062 72.988 1.00 83.48 N +ATOM 8949 CA VAL E 175 56.518 -30.406 73.555 1.00 81.36 C +ATOM 8950 C VAL E 175 55.996 -31.442 72.574 1.00 78.39 C +ATOM 8951 O VAL E 175 55.060 -31.191 71.822 1.00 68.13 O +ATOM 8952 CB VAL E 175 55.680 -30.454 74.857 1.00104.68 C +ATOM 8953 CG1 VAL E 175 56.301 -29.546 75.915 1.00132.01 C +ATOM 8954 CG2 VAL E 175 54.257 -30.032 74.612 1.00102.99 C +ATOM 8955 N ASN E 176 56.552 -32.651 72.660 1.00120.10 N +ATOM 8956 CA ASN E 176 56.235 -33.750 71.720 1.00136.86 C +ATOM 8957 C ASN E 176 55.781 -35.063 72.398 1.00117.27 C +ATOM 8958 O ASN E 176 56.623 -35.862 72.772 1.00 89.95 O +ATOM 8959 CB ASN E 176 57.492 -34.030 70.877 1.00130.27 C +ATOM 8960 CG ASN E 176 57.468 -33.345 69.515 1.00156.14 C +ATOM 8961 OD1 ASN E 176 58.296 -33.622 68.602 1.00 92.54 O +ATOM 8962 ND2 ASN E 176 56.524 -32.415 69.375 1.00184.89 N +ATOM 8963 N THR E 177 54.469 -35.266 72.575 1.00103.07 N +ATOM 8964 CA THR E 177 53.959 -36.433 73.310 1.00 92.11 C +ATOM 8965 C THR E 177 53.584 -37.540 72.344 1.00117.73 C +ATOM 8966 O THR E 177 53.359 -37.291 71.156 1.00129.49 O +ATOM 8967 CB THR E 177 52.743 -36.095 74.201 1.00 73.19 C +ATOM 8968 OG1 THR E 177 51.623 -35.778 73.379 1.00 66.07 O +ATOM 8969 CG2 THR E 177 53.045 -34.897 75.109 1.00 71.01 C +ATOM 8970 N SER E 178 53.515 -38.762 72.865 1.00140.79 N +ATOM 8971 CA SER E 178 53.243 -39.950 72.048 1.00164.62 C +ATOM 8972 C SER E 178 52.469 -41.005 72.843 1.00136.74 C +ATOM 8973 O SER E 178 52.521 -41.051 74.055 1.00101.16 O +ATOM 8974 CB SER E 178 54.539 -40.586 71.533 1.00160.52 C +ATOM 8975 OG SER E 178 54.292 -41.892 71.011 1.00109.17 O +ATOM 8976 N LYS E 179 51.730 -41.843 72.130 1.00140.05 N +ATOM 8977 CA LYS E 179 50.802 -42.750 72.781 1.00101.14 C +ATOM 8978 C LYS E 179 50.522 -43.920 71.850 1.00126.94 C +ATOM 8979 O LYS E 179 50.436 -43.780 70.612 1.00125.45 O +ATOM 8980 CB LYS E 179 49.511 -42.019 73.155 1.00 89.53 C +ATOM 8981 CG LYS E 179 48.900 -42.455 74.456 1.00 70.06 C +ATOM 8982 CD LYS E 179 47.860 -43.512 74.189 1.00104.40 C +ATOM 8983 CE LYS E 179 47.350 -44.091 75.495 1.00133.96 C +ATOM 8984 NZ LYS E 179 46.563 -45.334 75.274 1.00155.81 N +ATOM 8985 N THR E 180 50.365 -45.082 72.459 1.00144.12 N +ATOM 8986 CA THR E 180 50.198 -46.313 71.712 1.00168.60 C +ATOM 8987 C THR E 180 48.749 -46.822 71.803 1.00167.06 C +ATOM 8988 O THR E 180 48.152 -46.866 72.885 1.00104.12 O +ATOM 8989 CB THR E 180 51.190 -47.404 72.173 1.00177.89 C +ATOM 8990 OG1 THR E 180 50.657 -48.694 71.858 1.00199.45 O +ATOM 8991 CG2 THR E 180 51.457 -47.302 73.663 1.00177.81 C +ATOM 8992 N ILE E 181 48.189 -47.174 70.647 1.00161.53 N +ATOM 8993 CA ILE E 181 46.843 -47.710 70.581 1.00140.32 C +ATOM 8994 C ILE E 181 46.901 -49.245 70.513 1.00165.93 C +ATOM 8995 O ILE E 181 47.391 -49.814 69.523 1.00185.90 O +ATOM 8996 CB ILE E 181 46.075 -47.124 69.371 1.00111.60 C +ATOM 8997 CG1 ILE E 181 46.129 -45.603 69.399 1.00 86.86 C +ATOM 8998 CG2 ILE E 181 44.614 -47.555 69.373 1.00121.25 C +ATOM 8999 CD1 ILE E 181 46.795 -45.021 68.180 1.00121.15 C +ATOM 9000 N LEU E 182 46.336 -49.902 71.533 1.00143.65 N +ATOM 9001 CA LEU E 182 46.298 -51.371 71.614 1.00150.48 C +ATOM 9002 C LEU E 182 45.046 -52.049 71.000 1.00164.92 C +ATOM 9003 O LEU E 182 43.912 -51.586 71.186 1.00134.30 O +ATOM 9004 CB LEU E 182 46.397 -51.796 73.064 1.00128.15 C +ATOM 9005 CG LEU E 182 46.386 -53.303 73.301 1.00134.96 C +ATOM 9006 CD1 LEU E 182 47.565 -54.030 72.647 1.00118.48 C +ATOM 9007 CD2 LEU E 182 46.357 -53.532 74.799 1.00151.25 C +ATOM 9008 N SER E 183 45.271 -53.154 70.278 1.00158.97 N +ATOM 9009 CA SER E 183 44.188 -53.981 69.733 1.00137.32 C +ATOM 9010 C SER E 183 44.520 -55.463 69.883 1.00144.73 C +ATOM 9011 O SER E 183 45.680 -55.864 69.751 1.00132.43 O +ATOM 9012 CB SER E 183 43.968 -53.677 68.259 1.00120.05 C +ATOM 9013 OG SER E 183 44.129 -52.297 67.999 1.00142.37 O +ATOM 9014 N TYR E 184 43.518 -56.261 70.250 1.00153.00 N +ATOM 9015 CA TYR E 184 43.711 -57.702 70.369 1.00136.02 C +ATOM 9016 C TYR E 184 42.448 -58.519 70.086 1.00150.75 C +ATOM 9017 O TYR E 184 41.311 -58.062 70.269 1.00 92.37 O +ATOM 9018 CB TYR E 184 44.306 -58.078 71.732 1.00116.65 C +ATOM 9019 CG TYR E 184 43.466 -57.650 72.913 1.00123.61 C +ATOM 9020 CD1 TYR E 184 42.437 -58.455 73.384 1.00156.73 C +ATOM 9021 CD2 TYR E 184 43.724 -56.459 73.585 1.00102.48 C +ATOM 9022 CE1 TYR E 184 41.686 -58.073 74.482 1.00142.74 C +ATOM 9023 CE2 TYR E 184 42.984 -56.074 74.689 1.00 94.18 C +ATOM 9024 CZ TYR E 184 41.966 -56.878 75.128 1.00118.95 C +ATOM 9025 OH TYR E 184 41.210 -56.484 76.194 1.00126.60 O +ATOM 9026 N GLU E 185 42.682 -59.751 69.644 1.00194.16 N +ATOM 9027 CA GLU E 185 41.600 -60.666 69.220 1.00201.17 C +ATOM 9028 C GLU E 185 41.837 -62.073 69.804 1.00232.65 C +ATOM 9029 O GLU E 185 42.823 -62.739 69.496 1.00268.98 O +ATOM 9030 CB GLU E 185 41.414 -60.614 67.680 1.00156.78 C +ATOM 9031 CG GLU E 185 42.753 -60.600 66.956 1.00141.58 C +ATOM 9032 CD GLU E 185 42.819 -59.738 65.702 1.00139.28 C +ATOM 9033 OE1 GLU E 185 42.499 -58.568 65.882 1.00117.54 O +ATOM 9034 OE2 GLU E 185 43.355 -60.118 64.609 1.00164.43 O +ATOM 9035 N VAL E 186 40.998 -62.443 70.773 1.00204.15 N +ATOM 9036 CA VAL E 186 41.055 -63.746 71.415 1.00191.28 C +ATOM 9037 C VAL E 186 39.983 -64.653 70.816 1.00212.35 C +ATOM 9038 O VAL E 186 38.861 -64.216 70.572 1.00208.25 O +ATOM 9039 CB VAL E 186 40.837 -63.631 72.938 1.00180.78 C +ATOM 9040 CG1 VAL E 186 41.092 -64.968 73.610 1.00200.58 C +ATOM 9041 CG2 VAL E 186 41.749 -62.568 73.532 1.00195.44 C +ATOM 9042 N GLN E 187 40.341 -65.909 70.560 1.00227.07 N +ATOM 9043 CA GLN E 187 39.429 -66.845 69.904 1.00210.99 C +ATOM 9044 C GLN E 187 39.658 -68.269 70.384 1.00198.78 C +ATOM 9045 O GLN E 187 40.801 -68.705 70.523 1.00184.83 O +ATOM 9046 CB GLN E 187 39.642 -66.797 68.385 1.00206.26 C +ATOM 9047 CG GLN E 187 38.864 -65.725 67.634 1.00210.69 C +ATOM 9048 CD GLN E 187 39.421 -65.496 66.219 1.00225.19 C +ATOM 9049 OE1 GLN E 187 39.121 -64.494 65.540 1.00243.97 O +ATOM 9050 NE2 GLN E 187 40.214 -66.458 65.751 1.00196.18 N +ATOM 9051 N ALA E 188 38.568 -68.997 70.604 1.00198.18 N +ATOM 9052 CA ALA E 188 38.657 -70.407 70.965 1.00209.96 C +ATOM 9053 C ALA E 188 37.556 -71.207 70.277 1.00208.06 C +ATOM 9054 O ALA E 188 36.434 -70.734 70.158 1.00198.96 O +ATOM 9055 CB ALA E 188 38.586 -70.568 72.477 1.00205.36 C +ATOM 9056 N GLY E 189 37.888 -72.404 69.802 1.00189.39 N +ATOM 9057 CA GLY E 189 36.928 -73.243 69.097 1.00190.48 C +ATOM 9058 C GLY E 189 37.115 -74.725 69.361 1.00206.34 C +ATOM 9059 O GLY E 189 38.239 -75.215 69.426 1.00193.59 O +ATOM 9060 N VAL E 190 36.005 -75.438 69.534 1.00239.19 N +ATOM 9061 CA VAL E 190 36.034 -76.887 69.732 1.00238.47 C +ATOM 9062 C VAL E 190 35.366 -77.587 68.542 1.00242.31 C +ATOM 9063 O VAL E 190 34.318 -77.144 68.064 1.00248.20 O +ATOM 9064 CB VAL E 190 35.325 -77.288 71.041 1.00212.96 C +ATOM 9065 CG1 VAL E 190 35.589 -78.751 71.350 1.00213.32 C +ATOM 9066 CG2 VAL E 190 35.776 -76.395 72.196 1.00194.59 C +ATOM 9067 N PHE E 191 35.996 -78.649 68.038 1.00231.06 N +ATOM 9068 CA PHE E 191 35.571 -79.264 66.776 1.00225.85 C +ATOM 9069 C PHE E 191 35.488 -80.779 66.920 1.00206.28 C +ATOM 9070 O PHE E 191 36.428 -81.401 67.416 1.00216.09 O +ATOM 9071 CB PHE E 191 36.537 -78.869 65.643 1.00222.32 C +ATOM 9072 CG PHE E 191 35.953 -79.000 64.261 1.00240.93 C +ATOM 9073 CD1 PHE E 191 35.749 -80.250 63.697 1.00237.68 C +ATOM 9074 CD2 PHE E 191 35.633 -77.871 63.511 1.00229.89 C +ATOM 9075 CE1 PHE E 191 35.225 -80.376 62.421 1.00211.38 C +ATOM 9076 CE2 PHE E 191 35.097 -77.991 62.241 1.00210.01 C +ATOM 9077 CZ PHE E 191 34.905 -79.246 61.690 1.00198.36 C +ATOM 9078 N LEU E 200 30.112 -81.951 65.808 1.00184.28 N +ATOM 9079 CA LEU E 200 30.139 -80.889 66.807 1.00197.54 C +ATOM 9080 C LEU E 200 31.178 -79.826 66.467 1.00205.40 C +ATOM 9081 O LEU E 200 32.378 -80.103 66.473 1.00173.26 O +ATOM 9082 CB LEU E 200 30.460 -81.474 68.181 1.00186.40 C +ATOM 9083 CG LEU E 200 30.739 -80.427 69.275 1.00174.96 C +ATOM 9084 CD1 LEU E 200 29.507 -80.250 70.156 1.00150.90 C +ATOM 9085 CD2 LEU E 200 31.984 -80.750 70.103 1.00145.66 C +ATOM 9086 N GLU E 201 30.705 -78.607 66.206 1.00214.78 N +ATOM 9087 CA GLU E 201 31.551 -77.420 66.267 1.00211.96 C +ATOM 9088 C GLU E 201 31.015 -76.430 67.295 1.00207.65 C +ATOM 9089 O GLU E 201 29.808 -76.343 67.513 1.00189.50 O +ATOM 9090 CB GLU E 201 31.639 -76.738 64.903 1.00209.26 C +ATOM 9091 CG GLU E 201 32.841 -75.813 64.779 1.00208.31 C +ATOM 9092 CD GLU E 201 32.938 -75.131 63.425 1.00195.92 C +ATOM 9093 OE1 GLU E 201 32.866 -75.832 62.392 1.00193.52 O +ATOM 9094 OE2 GLU E 201 33.107 -73.894 63.397 1.00157.88 O +ATOM 9095 N GLY E 202 31.922 -75.699 67.938 1.00200.28 N +ATOM 9096 CA GLY E 202 31.547 -74.625 68.850 1.00189.30 C +ATOM 9097 C GLY E 202 32.647 -73.584 68.937 1.00172.06 C +ATOM 9098 O GLY E 202 33.797 -73.910 69.243 1.00219.97 O +ATOM 9099 N GLU E 203 32.298 -72.320 68.719 1.00137.11 N +ATOM 9100 CA GLU E 203 33.295 -71.249 68.728 1.00138.68 C +ATOM 9101 C GLU E 203 32.921 -70.051 69.610 1.00151.01 C +ATOM 9102 O GLU E 203 31.776 -69.595 69.612 1.00127.09 O +ATOM 9103 CB GLU E 203 33.547 -70.782 67.304 1.00144.48 C +ATOM 9104 CG GLU E 203 34.210 -71.845 66.436 1.00143.18 C +ATOM 9105 CD GLU E 203 34.566 -71.364 65.036 1.00180.93 C +ATOM 9106 OE1 GLU E 203 34.141 -70.250 64.650 1.00212.04 O +ATOM 9107 OE2 GLU E 203 35.230 -72.131 64.293 1.00201.54 O +ATOM 9108 N VAL E 204 33.915 -69.542 70.341 1.00163.35 N +ATOM 9109 CA VAL E 204 33.819 -68.276 71.063 1.00164.58 C +ATOM 9110 C VAL E 204 34.924 -67.335 70.577 1.00170.77 C +ATOM 9111 O VAL E 204 36.069 -67.749 70.402 1.00146.80 O +ATOM 9112 CB VAL E 204 33.927 -68.495 72.589 1.00148.00 C +ATOM 9113 CG1 VAL E 204 34.194 -67.189 73.331 1.00146.71 C +ATOM 9114 CG2 VAL E 204 32.652 -69.143 73.102 1.00154.41 C +ATOM 9115 N GLY E 205 34.558 -66.075 70.343 1.00160.00 N +ATOM 9116 CA GLY E 205 35.516 -65.053 69.952 1.00126.90 C +ATOM 9117 C GLY E 205 35.295 -63.737 70.691 1.00133.17 C +ATOM 9118 O GLY E 205 34.171 -63.407 71.078 1.00120.80 O +ATOM 9119 N TYR E 206 36.374 -62.980 70.883 1.00137.89 N +ATOM 9120 CA TYR E 206 36.307 -61.622 71.446 1.00130.93 C +ATOM 9121 C TYR E 206 37.407 -60.736 70.866 1.00149.29 C +ATOM 9122 O TYR E 206 38.512 -61.200 70.640 1.00149.82 O +ATOM 9123 CB TYR E 206 36.464 -61.664 72.958 1.00113.18 C +ATOM 9124 CG TYR E 206 36.476 -60.301 73.619 1.00 94.26 C +ATOM 9125 CD1 TYR E 206 35.290 -59.609 73.858 1.00104.27 C +ATOM 9126 CD2 TYR E 206 37.668 -59.732 74.065 1.00 83.31 C +ATOM 9127 CE1 TYR E 206 35.295 -58.373 74.504 1.00111.39 C +ATOM 9128 CE2 TYR E 206 37.684 -58.521 74.742 1.00 87.71 C +ATOM 9129 CZ TYR E 206 36.504 -57.824 74.940 1.00112.41 C +ATOM 9130 OH TYR E 206 36.543 -56.561 75.519 1.00 97.57 O +ATOM 9131 N THR E 207 37.088 -59.474 70.584 1.00153.23 N +ATOM 9132 CA THR E 207 38.074 -58.533 70.040 1.00145.89 C +ATOM 9133 C THR E 207 37.942 -57.171 70.716 1.00159.87 C +ATOM 9134 O THR E 207 36.826 -56.671 70.940 1.00140.60 O +ATOM 9135 CB THR E 207 37.922 -58.343 68.517 1.00135.11 C +ATOM 9136 OG1 THR E 207 36.627 -57.794 68.235 1.00174.40 O +ATOM 9137 CG2 THR E 207 38.070 -59.656 67.789 1.00130.27 C +ATOM 9138 N SER E 208 39.079 -56.572 71.063 1.00166.30 N +ATOM 9139 CA SER E 208 39.067 -55.256 71.709 1.00188.87 C +ATOM 9140 C SER E 208 40.072 -54.288 71.086 1.00204.36 C +ATOM 9141 O SER E 208 41.257 -54.591 70.987 1.00152.51 O +ATOM 9142 CB SER E 208 39.328 -55.375 73.213 1.00187.95 C +ATOM 9143 OG SER E 208 39.438 -54.088 73.802 1.00154.32 O +ATOM 9144 N ASN E 209 39.565 -53.131 70.659 1.00207.81 N +ATOM 9145 CA ASN E 209 40.387 -52.035 70.152 1.00146.87 C +ATOM 9146 C ASN E 209 40.308 -50.857 71.089 1.00167.43 C +ATOM 9147 O ASN E 209 39.227 -50.488 71.551 1.00188.08 O +ATOM 9148 CB ASN E 209 39.892 -51.575 68.794 1.00116.50 C +ATOM 9149 CG ASN E 209 40.155 -52.589 67.724 1.00110.95 C +ATOM 9150 OD1 ASN E 209 41.236 -52.635 67.153 1.00 83.56 O +ATOM 9151 ND2 ASN E 209 39.130 -53.365 67.390 1.00120.73 N +ATOM 9152 N GLU E 210 41.451 -50.246 71.348 1.00165.56 N +ATOM 9153 CA GLU E 210 41.451 -48.949 72.001 1.00148.00 C +ATOM 9154 C GLU E 210 40.852 -47.924 71.043 1.00109.82 C +ATOM 9155 O GLU E 210 41.094 -47.976 69.835 1.00110.04 O +ATOM 9156 CB GLU E 210 42.885 -48.553 72.380 1.00217.26 C +ATOM 9157 CG GLU E 210 43.043 -47.973 73.777 1.00237.31 C +ATOM 9158 CD GLU E 210 44.492 -47.997 74.262 1.00218.28 C +ATOM 9159 OE1 GLU E 210 45.307 -48.853 73.809 1.00112.49 O +ATOM 9160 OE2 GLU E 210 44.806 -47.136 75.107 1.00234.68 O +ATOM 9161 N PRO E 211 40.066 -46.994 71.567 1.00 96.88 N +ATOM 9162 CA PRO E 211 39.639 -45.881 70.740 1.00111.94 C +ATOM 9163 C PRO E 211 40.771 -44.890 70.445 1.00113.86 C +ATOM 9164 O PRO E 211 41.425 -44.396 71.365 1.00 95.81 O +ATOM 9165 CB PRO E 211 38.545 -45.214 71.577 1.00114.33 C +ATOM 9166 CG PRO E 211 38.152 -46.226 72.587 1.00123.02 C +ATOM 9167 CD PRO E 211 39.415 -46.976 72.874 1.00118.35 C +ATOM 9168 N VAL E 212 41.020 -44.645 69.153 1.00116.77 N +ATOM 9169 CA VAL E 212 42.055 -43.703 68.699 1.00 85.46 C +ATOM 9170 C VAL E 212 41.693 -42.300 69.160 1.00 75.44 C +ATOM 9171 O VAL E 212 42.531 -41.553 69.675 1.00 95.81 O +ATOM 9172 CB VAL E 212 42.181 -43.676 67.168 1.00 78.97 C +ATOM 9173 CG1 VAL E 212 43.342 -42.784 66.756 1.00 93.96 C +ATOM 9174 CG2 VAL E 212 42.356 -45.089 66.594 1.00 73.88 C +ATOM 9175 N MET E 213 40.416 -42.004 69.035 1.00 67.39 N +ATOM 9176 CA MET E 213 39.756 -40.918 69.728 1.00 99.52 C +ATOM 9177 C MET E 213 40.314 -40.645 71.146 1.00124.34 C +ATOM 9178 O MET E 213 40.640 -39.488 71.513 1.00177.84 O +ATOM 9179 CB MET E 213 38.271 -41.322 69.795 1.00106.42 C +ATOM 9180 CG MET E 213 37.272 -40.321 70.338 1.00116.37 C +ATOM 9181 SD MET E 213 35.637 -41.069 70.226 1.00100.48 S +ATOM 9182 CE MET E 213 35.404 -41.331 71.977 1.00148.29 C +ATOM 9183 N LEU E 214 40.373 -41.700 71.952 1.00106.31 N +ATOM 9184 CA LEU E 214 40.552 -41.567 73.394 1.00118.08 C +ATOM 9185 C LEU E 214 42.039 -41.444 73.679 1.00 87.60 C +ATOM 9186 O LEU E 214 42.451 -40.819 74.659 1.00 91.19 O +ATOM 9187 CB LEU E 214 39.940 -42.780 74.121 1.00119.57 C +ATOM 9188 CG LEU E 214 39.150 -42.563 75.431 1.00106.19 C +ATOM 9189 CD1 LEU E 214 37.942 -41.656 75.228 1.00 96.03 C +ATOM 9190 CD2 LEU E 214 38.709 -43.912 75.986 1.00108.68 C +ATOM 9191 N CYS E 215 42.835 -42.051 72.816 1.00 65.93 N +ATOM 9192 CA CYS E 215 44.287 -41.964 72.919 1.00 87.46 C +ATOM 9193 C CYS E 215 44.768 -40.556 72.559 1.00114.13 C +ATOM 9194 O CYS E 215 45.712 -40.005 73.177 1.00107.84 O +ATOM 9195 CB CYS E 215 44.956 -42.971 71.977 1.00 79.42 C +ATOM 9196 SG CYS E 215 44.611 -44.669 72.411 1.00120.08 S +ATOM 9197 N LEU E 216 44.151 -40.005 71.514 1.00125.75 N +ATOM 9198 CA LEU E 216 44.430 -38.645 71.106 1.00121.32 C +ATOM 9199 C LEU E 216 44.157 -37.719 72.303 1.00104.00 C +ATOM 9200 O LEU E 216 45.011 -36.886 72.650 1.00140.99 O +ATOM 9201 CB LEU E 216 43.584 -38.254 69.879 1.00 89.79 C +ATOM 9202 CG LEU E 216 43.772 -36.811 69.408 1.00 86.36 C +ATOM 9203 CD1 LEU E 216 45.226 -36.477 69.047 1.00 93.73 C +ATOM 9204 CD2 LEU E 216 42.896 -36.532 68.227 1.00 80.32 C +ATOM 9205 N MET E 217 43.006 -37.907 72.942 1.00 59.27 N +ATOM 9206 CA MET E 217 42.605 -37.027 74.009 1.00 53.82 C +ATOM 9207 C MET E 217 43.586 -37.130 75.152 1.00 69.42 C +ATOM 9208 O MET E 217 44.049 -36.124 75.684 1.00 76.61 O +ATOM 9209 CB MET E 217 41.203 -37.377 74.467 1.00 67.02 C +ATOM 9210 CG MET E 217 40.330 -36.152 74.715 1.00 91.71 C +ATOM 9211 SD MET E 217 40.849 -35.215 76.169 1.00113.64 S +ATOM 9212 CE MET E 217 39.866 -33.712 76.053 1.00116.16 C +ATOM 9213 N SER E 218 43.954 -38.365 75.512 1.00118.98 N +ATOM 9214 CA SER E 218 44.927 -38.647 76.614 1.00 93.86 C +ATOM 9215 C SER E 218 46.273 -37.998 76.380 1.00 81.90 C +ATOM 9216 O SER E 218 46.749 -37.227 77.233 1.00 91.09 O +ATOM 9217 CB SER E 218 45.164 -40.139 76.737 1.00 85.11 C +ATOM 9218 OG SER E 218 45.899 -40.427 77.894 1.00 87.87 O +ATOM 9219 N ALA E 219 46.806 -38.196 75.170 1.00 78.81 N +ATOM 9220 CA ALA E 219 48.072 -37.582 74.795 1.00 99.29 C +ATOM 9221 C ALA E 219 48.067 -36.016 74.817 1.00103.70 C +ATOM 9222 O ALA E 219 49.061 -35.376 75.224 1.00 73.63 O +ATOM 9223 CB ALA E 219 48.502 -38.090 73.435 1.00 90.28 C +ATOM 9224 N ILE E 220 46.955 -35.406 74.411 1.00 84.64 N +ATOM 9225 CA ILE E 220 46.837 -33.955 74.452 1.00 89.02 C +ATOM 9226 C ILE E 220 46.828 -33.423 75.894 1.00121.62 C +ATOM 9227 O ILE E 220 47.490 -32.426 76.209 1.00146.39 O +ATOM 9228 CB ILE E 220 45.584 -33.478 73.723 1.00 93.27 C +ATOM 9229 CG1 ILE E 220 45.755 -33.724 72.219 1.00118.79 C +ATOM 9230 CG2 ILE E 220 45.309 -31.999 74.012 1.00 80.75 C +ATOM 9231 CD1 ILE E 220 44.459 -33.662 71.428 1.00162.84 C +ATOM 9232 N GLU E 221 46.127 -34.117 76.785 1.00154.84 N +ATOM 9233 CA GLU E 221 46.137 -33.774 78.218 1.00152.16 C +ATOM 9234 C GLU E 221 47.559 -33.796 78.778 1.00121.13 C +ATOM 9235 O GLU E 221 48.018 -32.825 79.395 1.00103.49 O +ATOM 9236 CB GLU E 221 45.252 -34.752 79.013 1.00168.87 C +ATOM 9237 CG GLU E 221 43.762 -34.535 78.810 1.00182.16 C +ATOM 9238 CD GLU E 221 42.916 -35.715 79.270 1.00159.47 C +ATOM 9239 OE1 GLU E 221 43.316 -36.890 79.050 1.00128.04 O +ATOM 9240 OE2 GLU E 221 41.782 -35.448 79.718 1.00137.73 O +ATOM 9241 N THR E 222 48.245 -34.913 78.539 1.00 98.07 N +ATOM 9242 CA THR E 222 49.640 -35.098 78.932 1.00 94.40 C +ATOM 9243 C THR E 222 50.506 -33.930 78.454 1.00112.45 C +ATOM 9244 O THR E 222 51.300 -33.382 79.231 1.00101.06 O +ATOM 9245 CB THR E 222 50.199 -36.400 78.328 1.00 89.00 C +ATOM 9246 OG1 THR E 222 49.602 -37.534 78.986 1.00 93.55 O +ATOM 9247 CG2 THR E 222 51.736 -36.452 78.415 1.00 91.62 C +ATOM 9248 N GLY E 223 50.365 -33.581 77.172 1.00105.45 N +ATOM 9249 CA GLY E 223 51.074 -32.442 76.593 1.00 97.79 C +ATOM 9250 C GLY E 223 50.803 -31.158 77.359 1.00 99.40 C +ATOM 9251 O GLY E 223 51.709 -30.341 77.566 1.00109.35 O +ATOM 9252 N VAL E 224 49.549 -30.954 77.769 1.00103.47 N +ATOM 9253 CA VAL E 224 49.177 -29.732 78.486 1.00115.14 C +ATOM 9254 C VAL E 224 49.903 -29.682 79.824 1.00115.71 C +ATOM 9255 O VAL E 224 50.416 -28.630 80.216 1.00112.51 O +ATOM 9256 CB VAL E 224 47.656 -29.630 78.722 1.00118.31 C +ATOM 9257 CG1 VAL E 224 47.341 -28.446 79.633 1.00101.63 C +ATOM 9258 CG2 VAL E 224 46.914 -29.506 77.390 1.00113.34 C +ATOM 9259 N ILE E 225 49.975 -30.824 80.502 1.00111.45 N +ATOM 9260 CA ILE E 225 50.690 -30.893 81.765 1.00114.33 C +ATOM 9261 C ILE E 225 52.165 -30.537 81.565 1.00130.32 C +ATOM 9262 O ILE E 225 52.670 -29.653 82.267 1.00139.57 O +ATOM 9263 CB ILE E 225 50.571 -32.270 82.428 1.00117.80 C +ATOM 9264 CG1 ILE E 225 49.131 -32.518 82.888 1.00116.70 C +ATOM 9265 CG2 ILE E 225 51.495 -32.362 83.634 1.00136.93 C +ATOM 9266 CD1 ILE E 225 48.824 -33.979 83.158 1.00133.36 C +ATOM 9267 N PHE E 226 52.836 -31.194 80.608 1.00121.82 N +ATOM 9268 CA PHE E 226 54.260 -30.910 80.307 1.00114.64 C +ATOM 9269 C PHE E 226 54.494 -29.444 79.948 1.00121.68 C +ATOM 9270 O PHE E 226 55.516 -28.862 80.303 1.00123.07 O +ATOM 9271 CB PHE E 226 54.779 -31.769 79.159 1.00105.28 C +ATOM 9272 CG PHE E 226 55.145 -33.190 79.561 1.00134.08 C +ATOM 9273 CD1 PHE E 226 56.138 -33.430 80.505 1.00140.35 C +ATOM 9274 CD2 PHE E 226 54.561 -34.296 78.919 1.00124.51 C +ATOM 9275 CE1 PHE E 226 56.513 -34.733 80.824 1.00125.96 C +ATOM 9276 CE2 PHE E 226 54.957 -35.600 79.205 1.00 83.28 C +ATOM 9277 CZ PHE E 226 55.901 -35.818 80.188 1.00112.10 C +ATOM 9278 N LEU E 227 53.506 -28.825 79.312 1.00128.49 N +ATOM 9279 CA LEU E 227 53.565 -27.395 79.023 1.00129.13 C +ATOM 9280 C LEU E 227 53.513 -26.552 80.297 1.00120.35 C +ATOM 9281 O LEU E 227 54.271 -25.591 80.422 1.00145.59 O +ATOM 9282 CB LEU E 227 52.418 -27.010 78.083 1.00137.42 C +ATOM 9283 CG LEU E 227 52.606 -27.387 76.606 1.00126.96 C +ATOM 9284 CD1 LEU E 227 51.352 -27.284 75.754 1.00120.88 C +ATOM 9285 CD2 LEU E 227 53.719 -26.601 75.951 1.00105.89 C +ATOM 9286 N ILE E 228 52.615 -26.897 81.221 1.00 90.11 N +ATOM 9287 CA ILE E 228 52.441 -26.112 82.447 1.00 91.97 C +ATOM 9288 C ILE E 228 53.691 -26.240 83.295 1.00 96.18 C +ATOM 9289 O ILE E 228 54.238 -25.244 83.768 1.00 87.01 O +ATOM 9290 CB ILE E 228 51.228 -26.563 83.287 1.00 91.52 C +ATOM 9291 CG1 ILE E 228 49.913 -26.310 82.536 1.00115.04 C +ATOM 9292 CG2 ILE E 228 51.182 -25.801 84.599 1.00 72.63 C +ATOM 9293 CD1 ILE E 228 48.713 -27.046 83.102 1.00111.06 C +ATOM 9294 N ASN E 229 54.159 -27.472 83.449 1.00108.75 N +ATOM 9295 CA ASN E 229 55.365 -27.745 84.229 1.00118.36 C +ATOM 9296 C ASN E 229 56.588 -27.030 83.650 1.00105.95 C +ATOM 9297 O ASN E 229 57.339 -26.385 84.379 1.00116.92 O +ATOM 9298 CB ASN E 229 55.625 -29.253 84.276 1.00138.15 C +ATOM 9299 CG ASN E 229 56.600 -29.642 85.362 1.00150.82 C +ATOM 9300 OD1 ASN E 229 56.745 -28.939 86.369 1.00179.44 O +ATOM 9301 ND2 ASN E 229 57.224 -30.803 85.198 1.00149.94 N +ATOM 9302 N ASP E 230 56.739 -27.103 82.329 1.00 93.79 N +ATOM 9303 CA ASP E 230 57.801 -26.399 81.629 1.00 75.49 C +ATOM 9304 C ASP E 230 57.701 -24.877 81.861 1.00 90.71 C +ATOM 9305 O ASP E 230 58.711 -24.205 82.077 1.00 87.19 O +ATOM 9306 CB ASP E 230 57.743 -26.686 80.136 1.00 73.23 C +ATOM 9307 CG ASP E 230 58.923 -26.083 79.385 1.00 74.80 C +ATOM 9308 OD1 ASP E 230 60.001 -26.646 79.510 1.00 70.36 O +ATOM 9309 OD2 ASP E 230 58.732 -25.105 78.610 1.00108.21 O +ATOM 9310 N GLY E 231 56.479 -24.339 81.834 1.00 87.18 N +ATOM 9311 CA GLY E 231 56.269 -22.913 82.031 1.00 94.69 C +ATOM 9312 C GLY E 231 56.567 -22.487 83.457 1.00110.35 C +ATOM 9313 O GLY E 231 57.091 -21.375 83.695 1.00163.07 O +ATOM 9314 N ILE E 232 56.264 -23.370 84.409 1.00104.51 N +ATOM 9315 CA ILE E 232 56.631 -23.139 85.816 1.00129.80 C +ATOM 9316 C ILE E 232 58.152 -23.014 85.986 1.00118.82 C +ATOM 9317 O ILE E 232 58.634 -22.044 86.564 1.00100.90 O +ATOM 9318 CB ILE E 232 56.105 -24.267 86.733 1.00148.13 C +ATOM 9319 CG1 ILE E 232 54.588 -24.146 86.877 1.00143.24 C +ATOM 9320 CG2 ILE E 232 56.778 -24.228 88.105 1.00148.48 C +ATOM 9321 CD1 ILE E 232 53.923 -25.408 87.378 1.00174.14 C +ATOM 9322 N ASP E 233 58.889 -23.986 85.454 1.00108.35 N +ATOM 9323 CA ASP E 233 60.348 -23.954 85.458 1.00105.60 C +ATOM 9324 C ASP E 233 60.876 -22.665 84.833 1.00119.97 C +ATOM 9325 O ASP E 233 61.749 -22.013 85.401 1.00152.59 O +ATOM 9326 CB ASP E 233 60.926 -25.166 84.701 1.00116.37 C +ATOM 9327 CG ASP E 233 60.617 -26.501 85.385 1.00116.27 C +ATOM 9328 OD1 ASP E 233 59.770 -26.532 86.304 1.00127.91 O +ATOM 9329 OD2 ASP E 233 61.156 -27.533 84.933 1.00 97.80 O +ATOM 9330 N ARG E 234 60.380 -22.317 83.645 1.00158.65 N +ATOM 9331 CA ARG E 234 60.938 -21.199 82.867 1.00182.88 C +ATOM 9332 C ARG E 234 60.431 -19.825 83.299 1.00152.14 C +ATOM 9333 O ARG E 234 60.858 -18.805 82.758 1.00136.13 O +ATOM 9334 CB ARG E 234 60.662 -21.403 81.377 1.00200.67 C +ATOM 9335 CG ARG E 234 61.525 -22.501 80.782 1.00203.71 C +ATOM 9336 CD ARG E 234 60.936 -23.082 79.501 1.00175.17 C +ATOM 9337 NE ARG E 234 61.748 -24.199 79.032 1.00156.13 N +ATOM 9338 CZ ARG E 234 62.366 -24.242 77.857 1.00152.28 C +ATOM 9339 NH1 ARG E 234 62.150 -23.278 76.964 1.00157.39 N +ATOM 9340 NH2 ARG E 234 63.230 -25.222 77.582 1.00119.37 N +ATOM 9341 N GLY E 235 59.553 -19.798 84.298 1.00138.29 N +ATOM 9342 CA GLY E 235 59.080 -18.541 84.866 1.00117.72 C +ATOM 9343 C GLY E 235 58.069 -17.837 83.984 1.00 94.82 C +ATOM 9344 O GLY E 235 58.019 -16.605 83.957 1.00 75.45 O +ATOM 9345 N LEU E 236 57.265 -18.604 83.256 1.00101.14 N +ATOM 9346 CA LEU E 236 56.101 -18.020 82.574 1.00115.28 C +ATOM 9347 C LEU E 236 55.028 -17.701 83.606 1.00110.47 C +ATOM 9348 O LEU E 236 54.469 -16.607 83.619 1.00105.32 O +ATOM 9349 CB LEU E 236 55.530 -18.966 81.504 1.00140.93 C +ATOM 9350 CG LEU E 236 56.195 -18.969 80.116 1.00165.86 C +ATOM 9351 CD1 LEU E 236 57.490 -19.781 80.139 1.00148.22 C +ATOM 9352 CD2 LEU E 236 55.238 -19.533 79.070 1.00168.69 C +ATOM 9353 N TRP E 237 54.744 -18.668 84.470 1.00124.35 N +ATOM 9354 CA TRP E 237 53.700 -18.514 85.481 1.00134.33 C +ATOM 9355 C TRP E 237 54.162 -19.115 86.810 1.00149.56 C +ATOM 9356 O TRP E 237 55.142 -19.877 86.850 1.00120.40 O +ATOM 9357 CB TRP E 237 52.396 -19.158 84.998 1.00122.49 C +ATOM 9358 CG TRP E 237 52.622 -20.356 84.131 1.00130.82 C +ATOM 9359 CD1 TRP E 237 53.158 -21.545 84.518 1.00154.97 C +ATOM 9360 CD2 TRP E 237 52.330 -20.484 82.732 1.00133.48 C +ATOM 9361 NE1 TRP E 237 53.223 -22.408 83.447 1.00151.09 N +ATOM 9362 CE2 TRP E 237 52.710 -21.790 82.341 1.00130.93 C +ATOM 9363 CE3 TRP E 237 51.764 -19.636 81.784 1.00146.32 C +ATOM 9364 CZ2 TRP E 237 52.575 -22.257 81.032 1.00119.51 C +ATOM 9365 CZ3 TRP E 237 51.620 -20.104 80.485 1.00163.14 C +ATOM 9366 CH2 TRP E 237 52.018 -21.410 80.125 1.00145.65 C +ATOM 9367 N ASP E 238 53.454 -18.770 87.888 1.00155.78 N +ATOM 9368 CA ASP E 238 53.863 -19.147 89.241 1.00161.92 C +ATOM 9369 C ASP E 238 52.751 -19.810 90.063 1.00155.15 C +ATOM 9370 O ASP E 238 51.567 -19.523 89.906 1.00 91.09 O +ATOM 9371 CB ASP E 238 54.377 -17.934 90.014 1.00149.90 C +ATOM 9372 CG ASP E 238 55.509 -17.227 89.303 1.00145.26 C +ATOM 9373 OD1 ASP E 238 55.220 -16.472 88.361 1.00140.90 O +ATOM 9374 OD2 ASP E 238 56.682 -17.440 89.668 1.00163.32 O +ATOM 9375 N LEU E 239 53.171 -20.699 90.957 1.00149.29 N +ATOM 9376 CA LEU E 239 52.264 -21.483 91.769 1.00120.75 C +ATOM 9377 C LEU E 239 51.773 -20.668 92.949 1.00132.18 C +ATOM 9378 O LEU E 239 52.481 -19.793 93.456 1.00122.76 O +ATOM 9379 CB LEU E 239 52.966 -22.781 92.177 1.00114.12 C +ATOM 9380 CG LEU E 239 52.087 -23.933 92.687 1.00129.86 C +ATOM 9381 CD1 LEU E 239 50.902 -24.046 91.740 1.00129.08 C +ATOM 9382 CD2 LEU E 239 52.886 -25.226 92.676 1.00134.47 C +ATOM 9383 N GLN E 240 50.503 -20.865 93.298 1.00147.74 N +ATOM 9384 CA GLN E 240 49.929 -20.250 94.500 1.00127.30 C +ATOM 9385 C GLN E 240 50.777 -20.597 95.721 1.00132.29 C +ATOM 9386 O GLN E 240 51.288 -19.707 96.411 1.00140.99 O +ATOM 9387 CB GLN E 240 48.491 -20.734 94.714 1.00116.34 C +ATOM 9388 CG GLN E 240 47.763 -20.004 95.833 1.00125.35 C +ATOM 9389 CD GLN E 240 47.554 -18.533 95.514 1.00116.07 C +ATOM 9390 OE1 GLN E 240 46.622 -18.173 94.794 1.00116.14 O +ATOM 9391 NE2 GLN E 240 48.429 -17.677 96.038 1.00115.31 N +ATOM 9392 N ASN E 241 50.961 -21.896 95.933 1.00137.63 N +ATOM 9393 CA ASN E 241 51.780 -22.407 97.024 1.00149.25 C +ATOM 9394 C ASN E 241 53.116 -22.914 96.516 1.00143.71 C +ATOM 9395 O ASN E 241 53.184 -23.954 95.837 1.00148.89 O +ATOM 9396 CB ASN E 241 51.052 -23.551 97.717 1.00161.11 C +ATOM 9397 CG ASN E 241 50.384 -23.119 98.997 1.00172.92 C +ATOM 9398 OD1 ASN E 241 50.907 -23.369 100.079 1.00189.90 O +ATOM 9399 ND2 ASN E 241 49.240 -22.446 98.886 1.00163.65 N +ATOM 9400 N LYS E 242 54.181 -22.198 96.866 1.00126.94 N +ATOM 9401 CA LYS E 242 55.520 -22.576 96.428 1.00138.23 C +ATOM 9402 C LYS E 242 55.899 -23.901 97.071 1.00152.98 C +ATOM 9403 O LYS E 242 56.708 -24.665 96.525 1.00147.07 O +ATOM 9404 CB LYS E 242 56.534 -21.480 96.774 1.00156.24 C +ATOM 9405 CG LYS E 242 56.105 -20.079 96.338 1.00161.80 C +ATOM 9406 CD LYS E 242 57.157 -19.397 95.473 1.00171.22 C +ATOM 9407 CE LYS E 242 56.528 -18.761 94.242 1.00166.30 C +ATOM 9408 NZ LYS E 242 57.502 -17.959 93.456 1.00171.08 N +ATOM 9409 N ALA E 243 55.269 -24.170 98.219 1.00173.15 N +ATOM 9410 CA ALA E 243 55.398 -25.438 98.937 1.00186.17 C +ATOM 9411 C ALA E 243 54.879 -26.608 98.106 1.00203.45 C +ATOM 9412 O ALA E 243 55.218 -27.765 98.388 1.00247.48 O +ATOM 9413 CB ALA E 243 54.647 -25.373 100.263 1.00156.07 C +ATOM 9414 N GLU E 244 54.059 -26.314 97.094 1.00178.25 N +ATOM 9415 CA GLU E 244 53.477 -27.373 96.281 1.00146.39 C +ATOM 9416 C GLU E 244 54.308 -27.672 95.037 1.00130.18 C +ATOM 9417 O GLU E 244 53.838 -28.398 94.173 1.00144.55 O +ATOM 9418 CB GLU E 244 52.042 -27.020 95.883 1.00135.44 C +ATOM 9419 CG GLU E 244 51.038 -27.116 97.025 1.00130.57 C +ATOM 9420 CD GLU E 244 49.595 -27.018 96.557 1.00141.93 C +ATOM 9421 OE1 GLU E 244 49.141 -25.893 96.236 1.00144.10 O +ATOM 9422 OE2 GLU E 244 48.920 -28.071 96.485 1.00123.77 O +ATOM 9423 N ARG E 245 55.534 -27.141 94.973 1.00115.19 N +ATOM 9424 CA ARG E 245 56.503 -27.478 93.917 1.00147.40 C +ATOM 9425 C ARG E 245 56.747 -28.992 93.790 1.00136.73 C +ATOM 9426 O ARG E 245 56.842 -29.540 92.676 1.00104.01 O +ATOM 9427 CB ARG E 245 57.856 -26.678 94.129 1.00189.22 C +ATOM 9428 CG ARG E 245 57.777 -25.377 93.356 1.00197.40 C +ATOM 9429 CD ARG E 245 59.113 -24.841 92.942 1.00196.31 C +ATOM 9430 NE ARG E 245 59.199 -24.885 91.486 1.00181.50 N +ATOM 9431 CZ ARG E 245 59.454 -25.971 90.748 1.00146.87 C +ATOM 9432 NH1 ARG E 245 59.757 -27.131 91.304 1.00107.58 N +ATOM 9433 NH2 ARG E 245 59.442 -25.875 89.425 1.00154.10 N +ATOM 9434 N GLN E 246 56.808 -29.677 94.929 1.00144.27 N +ATOM 9435 CA GLN E 246 57.121 -31.107 94.938 1.00146.94 C +ATOM 9436 C GLN E 246 55.854 -31.970 94.938 1.00150.52 C +ATOM 9437 O GLN E 246 55.888 -33.137 95.324 1.00174.11 O +ATOM 9438 CB GLN E 246 58.004 -31.463 96.140 1.00132.31 C +ATOM 9439 CG GLN E 246 59.424 -30.937 96.050 1.00121.83 C +ATOM 9440 CD GLN E 246 59.510 -29.448 96.316 1.00147.23 C +ATOM 9441 OE1 GLN E 246 58.896 -28.935 97.256 1.00166.37 O +ATOM 9442 NE2 GLN E 246 60.287 -28.745 95.500 1.00177.18 N +ATOM 9443 N ASN E 247 54.746 -31.392 94.483 1.00139.32 N +ATOM 9444 CA ASN E 247 53.530 -32.143 94.160 1.00136.41 C +ATOM 9445 C ASN E 247 53.819 -33.454 93.427 1.00132.53 C +ATOM 9446 O ASN E 247 54.676 -33.491 92.537 1.00150.70 O +ATOM 9447 CB ASN E 247 52.629 -31.288 93.273 1.00146.69 C +ATOM 9448 CG ASN E 247 51.178 -31.663 93.399 1.00145.43 C +ATOM 9449 OD1 ASN E 247 50.579 -32.210 92.466 1.00130.46 O +ATOM 9450 ND2 ASN E 247 50.583 -31.317 94.538 1.00142.21 N +ATOM 9451 N ASP E 248 53.115 -34.521 93.806 1.00137.43 N +ATOM 9452 CA ASP E 248 53.355 -35.867 93.242 1.00166.26 C +ATOM 9453 C ASP E 248 53.310 -35.844 91.714 1.00172.11 C +ATOM 9454 O ASP E 248 54.166 -36.423 91.034 1.00153.38 O +ATOM 9455 CB ASP E 248 52.300 -36.868 93.744 1.00164.80 C +ATOM 9456 CG ASP E 248 52.482 -37.245 95.203 1.00173.41 C +ATOM 9457 OD1 ASP E 248 53.635 -37.386 95.658 1.00183.28 O +ATOM 9458 OD2 ASP E 248 51.457 -37.402 95.898 1.00187.78 O +ATOM 9459 N ILE E 249 52.286 -35.180 91.190 1.00168.28 N +ATOM 9460 CA ILE E 249 52.046 -35.134 89.760 1.00159.29 C +ATOM 9461 C ILE E 249 53.164 -34.350 89.068 1.00153.80 C +ATOM 9462 O ILE E 249 53.772 -34.818 88.100 1.00162.98 O +ATOM 9463 CB ILE E 249 50.678 -34.490 89.465 1.00161.07 C +ATOM 9464 CG1 ILE E 249 49.545 -35.340 90.060 1.00152.55 C +ATOM 9465 CG2 ILE E 249 50.475 -34.350 87.964 1.00194.10 C +ATOM 9466 CD1 ILE E 249 48.239 -34.593 90.254 1.00143.63 C +ATOM 9467 N LEU E 250 53.463 -33.170 89.605 1.00141.85 N +ATOM 9468 CA LEU E 250 54.481 -32.289 89.020 1.00137.49 C +ATOM 9469 C LEU E 250 55.866 -32.929 88.977 1.00141.53 C +ATOM 9470 O LEU E 250 56.603 -32.743 88.009 1.00133.19 O +ATOM 9471 CB LEU E 250 54.549 -30.965 89.784 1.00133.32 C +ATOM 9472 CG LEU E 250 53.460 -29.945 89.430 1.00135.89 C +ATOM 9473 CD1 LEU E 250 53.410 -28.792 90.424 1.00129.44 C +ATOM 9474 CD2 LEU E 250 53.682 -29.417 88.025 1.00139.40 C +ATOM 9475 N VAL E 251 56.207 -33.684 90.021 1.00153.89 N +ATOM 9476 CA VAL E 251 57.498 -34.379 90.067 1.00156.98 C +ATOM 9477 C VAL E 251 57.500 -35.629 89.187 1.00164.64 C +ATOM 9478 O VAL E 251 58.555 -36.068 88.723 1.00183.53 O +ATOM 9479 CB VAL E 251 57.916 -34.763 91.505 1.00136.81 C +ATOM 9480 CG1 VAL E 251 57.916 -33.531 92.401 1.00138.47 C +ATOM 9481 CG2 VAL E 251 57.023 -35.864 92.067 1.00127.23 C +ATOM 9482 N LYS E 252 56.320 -36.197 88.960 1.00148.06 N +ATOM 9483 CA LYS E 252 56.182 -37.331 88.055 1.00141.13 C +ATOM 9484 C LYS E 252 56.496 -36.909 86.606 1.00153.87 C +ATOM 9485 O LYS E 252 57.268 -37.570 85.897 1.00119.88 O +ATOM 9486 CB LYS E 252 54.768 -37.901 88.183 1.00123.01 C +ATOM 9487 CG LYS E 252 54.463 -39.080 87.279 1.00122.71 C +ATOM 9488 CD LYS E 252 53.026 -39.531 87.486 1.00129.65 C +ATOM 9489 CE LYS E 252 52.307 -39.735 86.160 1.00165.44 C +ATOM 9490 NZ LYS E 252 50.834 -39.917 86.321 1.00152.27 N +ATOM 9491 N TYR E 253 55.929 -35.778 86.186 1.00170.78 N +ATOM 9492 CA TYR E 253 56.135 -35.265 84.825 1.00160.07 C +ATOM 9493 C TYR E 253 57.497 -34.610 84.681 1.00152.61 C +ATOM 9494 O TYR E 253 58.106 -34.641 83.603 1.00129.06 O +ATOM 9495 CB TYR E 253 55.016 -34.290 84.430 1.00157.91 C +ATOM 9496 CG TYR E 253 53.702 -35.023 84.189 1.00186.54 C +ATOM 9497 CD1 TYR E 253 53.425 -35.615 82.954 1.00182.13 C +ATOM 9498 CD2 TYR E 253 52.779 -35.203 85.219 1.00184.04 C +ATOM 9499 CE1 TYR E 253 52.252 -36.317 82.747 1.00148.00 C +ATOM 9500 CE2 TYR E 253 51.592 -35.898 85.010 1.00133.50 C +ATOM 9501 CZ TYR E 253 51.334 -36.442 83.773 1.00124.20 C +ATOM 9502 OH TYR E 253 50.173 -37.124 83.548 1.00 95.29 O +ATOM 9503 N ARG E 254 57.968 -34.011 85.771 1.00154.64 N +ATOM 9504 CA ARG E 254 59.342 -33.523 85.843 1.00152.36 C +ATOM 9505 C ARG E 254 60.315 -34.680 85.601 1.00133.52 C +ATOM 9506 O ARG E 254 61.329 -34.511 84.910 1.00125.21 O +ATOM 9507 CB ARG E 254 59.621 -32.886 87.214 1.00170.84 C +ATOM 9508 CG ARG E 254 61.001 -32.256 87.320 1.00175.25 C +ATOM 9509 CD ARG E 254 61.119 -31.290 88.487 1.00178.47 C +ATOM 9510 NE ARG E 254 60.275 -30.101 88.356 1.00164.87 N +ATOM 9511 CZ ARG E 254 59.173 -29.857 89.063 1.00163.16 C +ATOM 9512 NH1 ARG E 254 58.727 -30.738 89.955 1.00170.16 N +ATOM 9513 NH2 ARG E 254 58.505 -28.725 88.874 1.00160.98 N +ATOM 9514 N HIS E 255 59.992 -35.847 86.166 1.00131.36 N +ATOM 9515 CA HIS E 255 60.824 -37.045 86.030 1.00149.32 C +ATOM 9516 C HIS E 255 60.816 -37.617 84.616 1.00150.28 C +ATOM 9517 O HIS E 255 61.839 -38.116 84.139 1.00177.09 O +ATOM 9518 CB HIS E 255 60.391 -38.130 87.023 1.00156.41 C +ATOM 9519 CG HIS E 255 61.326 -38.306 88.176 1.00171.07 C +ATOM 9520 ND1 HIS E 255 61.390 -37.414 89.225 1.00161.86 N +ATOM 9521 CD2 HIS E 255 62.238 -39.271 88.444 1.00179.65 C +ATOM 9522 CE1 HIS E 255 62.310 -37.817 90.084 1.00184.67 C +ATOM 9523 NE2 HIS E 255 62.839 -38.941 89.634 1.00187.57 N +ATOM 9524 N MET E 256 59.687 -37.516 83.926 1.00143.54 N +ATOM 9525 CA MET E 256 59.623 -38.000 82.546 1.00143.43 C +ATOM 9526 C MET E 256 60.504 -37.159 81.591 1.00166.38 C +ATOM 9527 O MET E 256 60.939 -37.661 80.545 1.00140.55 O +ATOM 9528 CB MET E 256 58.168 -38.056 82.069 1.00153.13 C +ATOM 9529 CG MET E 256 57.246 -38.835 83.004 1.00155.80 C +ATOM 9530 SD MET E 256 55.684 -39.385 82.283 1.00169.07 S +ATOM 9531 CE MET E 256 56.292 -40.642 81.146 1.00146.30 C +ATOM 9532 N SER E 257 60.775 -35.901 81.969 1.00172.08 N +ATOM 9533 CA SER E 257 61.688 -35.017 81.228 1.00140.14 C +ATOM 9534 C SER E 257 63.140 -35.378 81.502 1.00113.46 C +ATOM 9535 O SER E 257 63.707 -36.222 80.798 1.00142.40 O +ATOM 9536 CB SER E 257 61.457 -33.553 81.610 1.00121.90 C +ATOM 9537 OG SER E 257 60.068 -33.270 81.700 1.00 97.17 O +TER 9538 SER E 257 +ATOM 9539 N LEU F 2 28.960 -55.358 80.031 1.00144.49 N +ATOM 9540 CA LEU F 2 29.905 -54.413 79.288 1.00138.92 C +ATOM 9541 C LEU F 2 29.819 -54.169 77.758 1.00139.36 C +ATOM 9542 O LEU F 2 30.268 -54.994 76.953 1.00105.87 O +ATOM 9543 CB LEU F 2 31.350 -54.790 79.579 1.00134.07 C +ATOM 9544 CG LEU F 2 31.893 -54.710 81.016 1.00125.33 C +ATOM 9545 CD1 LEU F 2 33.358 -55.134 81.015 1.00119.08 C +ATOM 9546 CD2 LEU F 2 31.731 -53.339 81.676 1.00109.96 C +ATOM 9547 N THR F 3 29.356 -52.966 77.398 1.00152.83 N +ATOM 9548 CA THR F 3 29.167 -52.507 76.006 1.00166.11 C +ATOM 9549 C THR F 3 29.315 -50.966 75.874 1.00174.06 C +ATOM 9550 O THR F 3 29.166 -50.381 74.780 1.00118.81 O +ATOM 9551 CB THR F 3 27.763 -52.885 75.501 1.00165.74 C +ATOM 9552 OG1 THR F 3 26.769 -52.127 76.220 1.00165.31 O +ATOM 9553 CG2 THR F 3 27.529 -54.391 75.658 1.00154.81 C +ATOM 9554 N ALA F 4 29.551 -50.302 76.999 1.00174.02 N +ATOM 9555 CA ALA F 4 30.147 -48.971 76.985 1.00143.29 C +ATOM 9556 C ALA F 4 31.641 -49.126 76.624 1.00133.90 C +ATOM 9557 O ALA F 4 32.104 -50.223 76.310 1.00100.74 O +ATOM 9558 CB ALA F 4 29.950 -48.287 78.337 1.00129.02 C +ATOM 9559 N PRO F 5 32.409 -48.030 76.622 1.00141.79 N +ATOM 9560 CA PRO F 5 33.686 -48.260 75.962 1.00131.07 C +ATOM 9561 C PRO F 5 34.702 -48.998 76.839 1.00109.65 C +ATOM 9562 O PRO F 5 34.513 -49.118 78.047 1.00121.20 O +ATOM 9563 CB PRO F 5 34.148 -46.834 75.625 1.00150.98 C +ATOM 9564 CG PRO F 5 33.503 -45.944 76.656 1.00138.45 C +ATOM 9565 CD PRO F 5 32.322 -46.682 77.229 1.00141.89 C +ATOM 9566 N PRO F 6 35.810 -49.432 76.246 1.00 96.43 N +ATOM 9567 CA PRO F 6 36.998 -49.825 77.021 1.00105.52 C +ATOM 9568 C PRO F 6 37.827 -48.654 77.528 1.00 96.19 C +ATOM 9569 O PRO F 6 37.865 -47.605 76.898 1.00 72.09 O +ATOM 9570 CB PRO F 6 37.809 -50.674 76.038 1.00112.95 C +ATOM 9571 CG PRO F 6 37.293 -50.335 74.682 1.00106.73 C +ATOM 9572 CD PRO F 6 35.953 -49.673 74.806 1.00 93.16 C +ATOM 9573 N LYS F 7 38.551 -48.852 78.624 1.00123.65 N +ATOM 9574 CA LYS F 7 39.385 -47.779 79.162 1.00160.02 C +ATOM 9575 C LYS F 7 40.843 -47.879 78.709 1.00151.65 C +ATOM 9576 O LYS F 7 41.295 -48.923 78.195 1.00100.80 O +ATOM 9577 CB LYS F 7 39.307 -47.724 80.693 1.00182.88 C +ATOM 9578 CG LYS F 7 37.959 -47.302 81.240 1.00192.26 C +ATOM 9579 CD LYS F 7 37.144 -48.468 81.792 1.00184.89 C +ATOM 9580 CE LYS F 7 35.960 -47.962 82.597 1.00178.02 C +ATOM 9581 NZ LYS F 7 34.815 -48.913 82.565 1.00163.55 N +ATOM 9582 N GLU F 8 41.583 -46.786 78.916 1.00179.10 N +ATOM 9583 CA GLU F 8 42.898 -46.612 78.259 1.00212.17 C +ATOM 9584 C GLU F 8 44.009 -47.531 78.760 1.00174.04 C +ATOM 9585 O GLU F 8 44.320 -47.583 79.936 1.00129.00 O +ATOM 9586 CB GLU F 8 43.359 -45.158 78.086 1.00240.80 C +ATOM 9587 CG GLU F 8 42.569 -44.074 78.739 1.00242.71 C +ATOM 9588 CD GLU F 8 42.990 -42.675 78.264 1.00188.64 C +ATOM 9589 OE1 GLU F 8 44.186 -42.323 78.381 1.00164.20 O +ATOM 9590 OE2 GLU F 8 42.125 -41.894 77.826 1.00104.26 O +ATOM 9591 N ALA F 9 44.535 -48.329 77.839 1.00155.22 N +ATOM 9592 CA ALA F 9 45.661 -49.228 78.101 1.00134.62 C +ATOM 9593 C ALA F 9 46.991 -48.612 77.644 1.00144.08 C +ATOM 9594 O ALA F 9 47.140 -48.333 76.461 1.00200.30 O +ATOM 9595 CB ALA F 9 45.421 -50.528 77.360 1.00128.04 C +ATOM 9596 N ALA F 10 47.942 -48.440 78.572 1.00124.46 N +ATOM 9597 CA ALA F 10 49.229 -47.764 78.329 1.00117.31 C +ATOM 9598 C ALA F 10 49.142 -46.238 78.427 1.00132.06 C +ATOM 9599 O ALA F 10 48.062 -45.652 78.271 1.00125.13 O +ATOM 9600 CB ALA F 10 49.846 -48.198 77.006 1.00 86.11 C +ATOM 9601 N ARG F 11 50.292 -45.605 78.692 1.00151.61 N +ATOM 9602 CA ARG F 11 50.347 -44.190 79.077 1.00158.33 C +ATOM 9603 C ARG F 11 50.915 -43.297 77.971 1.00151.56 C +ATOM 9604 O ARG F 11 51.758 -43.724 77.179 1.00164.99 O +ATOM 9605 CB ARG F 11 51.227 -44.016 80.325 1.00179.31 C +ATOM 9606 CG ARG F 11 52.713 -44.252 80.098 1.00185.60 C +ATOM 9607 CD ARG F 11 53.398 -44.705 81.380 1.00181.79 C +ATOM 9608 NE ARG F 11 53.863 -46.069 81.256 1.00191.65 N +ATOM 9609 CZ ARG F 11 53.104 -47.171 81.197 1.00190.88 C +ATOM 9610 NH1 ARG F 11 51.771 -47.143 81.276 1.00196.30 N +ATOM 9611 NH2 ARG F 11 53.708 -48.348 81.069 1.00194.80 N +ATOM 9612 N PRO F 12 50.497 -42.026 77.943 1.00138.95 N +ATOM 9613 CA PRO F 12 51.212 -41.088 77.096 1.00144.35 C +ATOM 9614 C PRO F 12 52.610 -40.851 77.643 1.00125.13 C +ATOM 9615 O PRO F 12 52.771 -40.364 78.768 1.00167.90 O +ATOM 9616 CB PRO F 12 50.377 -39.800 77.186 1.00172.69 C +ATOM 9617 CG PRO F 12 49.077 -40.193 77.800 1.00171.18 C +ATOM 9618 CD PRO F 12 49.391 -41.381 78.662 1.00151.31 C +ATOM 9619 N THR F 13 53.610 -41.256 76.876 1.00102.27 N +ATOM 9620 CA THR F 13 54.983 -40.867 77.144 1.00103.75 C +ATOM 9621 C THR F 13 55.331 -39.613 76.338 1.00112.47 C +ATOM 9622 O THR F 13 54.682 -39.354 75.335 1.00154.46 O +ATOM 9623 CB THR F 13 55.942 -42.020 76.776 1.00 87.88 C +ATOM 9624 OG1 THR F 13 57.260 -41.693 77.262 1.00161.19 O +ATOM 9625 CG2 THR F 13 55.967 -42.293 75.249 1.00 54.96 C +ATOM 9626 N LEU F 14 56.366 -38.866 76.726 1.00106.98 N +ATOM 9627 CA LEU F 14 56.890 -37.877 75.789 1.00102.74 C +ATOM 9628 C LEU F 14 57.678 -38.583 74.654 1.00114.31 C +ATOM 9629 O LEU F 14 57.993 -39.752 74.778 1.00126.78 O +ATOM 9630 CB LEU F 14 57.693 -36.780 76.460 1.00 83.69 C +ATOM 9631 CG LEU F 14 58.878 -37.181 77.298 1.00 98.97 C +ATOM 9632 CD1 LEU F 14 59.976 -36.135 77.203 1.00102.30 C +ATOM 9633 CD2 LEU F 14 58.405 -37.314 78.721 1.00134.38 C +ATOM 9634 N MET F 15 57.796 -37.946 73.488 1.00120.93 N +ATOM 9635 CA MET F 15 57.949 -38.688 72.221 1.00119.78 C +ATOM 9636 C MET F 15 59.328 -39.324 72.181 1.00 95.51 C +ATOM 9637 O MET F 15 60.330 -38.628 72.301 1.00 76.62 O +ATOM 9638 CB MET F 15 57.699 -37.805 70.980 1.00125.29 C +ATOM 9639 CG MET F 15 57.196 -38.602 69.783 1.00110.05 C +ATOM 9640 SD MET F 15 57.797 -38.259 68.128 1.00117.40 S +ATOM 9641 CE MET F 15 59.200 -37.166 68.267 1.00 84.01 C +ATOM 9642 N PRO F 16 59.370 -40.652 72.009 1.00 93.29 N +ATOM 9643 CA PRO F 16 60.585 -41.449 72.091 1.00105.30 C +ATOM 9644 C PRO F 16 61.636 -41.113 71.017 1.00103.60 C +ATOM 9645 O PRO F 16 61.809 -41.844 70.047 1.00 92.06 O +ATOM 9646 CB PRO F 16 60.069 -42.893 71.945 1.00106.70 C +ATOM 9647 CG PRO F 16 58.804 -42.759 71.200 1.00105.97 C +ATOM 9648 CD PRO F 16 58.198 -41.487 71.700 1.00100.51 C +ATOM 9649 N ARG F 17 62.415 -40.067 71.273 1.00113.34 N +ATOM 9650 CA ARG F 17 63.584 -39.742 70.459 1.00 97.66 C +ATOM 9651 C ARG F 17 64.803 -40.504 70.980 1.00103.37 C +ATOM 9652 O ARG F 17 64.936 -40.688 72.188 1.00 99.97 O +ATOM 9653 CB ARG F 17 63.828 -38.221 70.499 1.00 70.22 C +ATOM 9654 CG ARG F 17 63.034 -37.460 69.453 1.00 66.56 C +ATOM 9655 CD ARG F 17 62.933 -35.966 69.716 1.00 62.11 C +ATOM 9656 NE ARG F 17 61.945 -35.679 70.741 1.00 84.24 N +ATOM 9657 CZ ARG F 17 61.736 -34.476 71.255 1.00117.49 C +ATOM 9658 NH1 ARG F 17 62.430 -33.441 70.800 1.00126.47 N +ATOM 9659 NH2 ARG F 17 60.805 -34.304 72.204 1.00143.85 N +ATOM 9660 N ALA F 18 65.708 -40.907 70.091 1.00102.17 N +ATOM 9661 CA ALA F 18 66.897 -41.654 70.517 1.00121.21 C +ATOM 9662 C ALA F 18 68.246 -40.899 70.385 1.00112.10 C +ATOM 9663 O ALA F 18 68.456 -39.863 71.018 1.00 74.16 O +ATOM 9664 CB ALA F 18 66.947 -42.987 69.791 1.00155.92 C +ATOM 9665 N GLN F 19 69.150 -41.420 69.560 1.00125.99 N +ATOM 9666 CA GLN F 19 70.554 -41.035 69.633 1.00129.22 C +ATOM 9667 C GLN F 19 70.788 -39.610 69.131 1.00120.53 C +ATOM 9668 O GLN F 19 71.466 -38.801 69.781 1.00106.49 O +ATOM 9669 CB GLN F 19 71.400 -42.012 68.808 1.00168.51 C +ATOM 9670 CG GLN F 19 72.902 -41.793 68.932 1.00211.87 C +ATOM 9671 CD GLN F 19 73.381 -41.799 70.374 1.00209.87 C +ATOM 9672 OE1 GLN F 19 73.335 -42.835 71.045 1.00244.58 O +ATOM 9673 NE2 GLN F 19 73.842 -40.646 70.857 1.00162.09 N +ATOM 9674 N SER F 20 70.248 -39.335 67.942 1.00124.84 N +ATOM 9675 CA SER F 20 70.251 -37.999 67.347 1.00108.74 C +ATOM 9676 C SER F 20 69.900 -36.926 68.398 1.00101.84 C +ATOM 9677 O SER F 20 70.626 -35.954 68.561 1.00131.45 O +ATOM 9678 CB SER F 20 69.250 -37.957 66.181 1.00 94.00 C +ATOM 9679 OG SER F 20 69.461 -39.027 65.287 1.00 71.84 O +ATOM 9680 N TYR F 21 68.819 -37.157 69.140 1.00 77.44 N +ATOM 9681 CA TYR F 21 68.394 -36.281 70.228 1.00 74.39 C +ATOM 9682 C TYR F 21 69.458 -36.077 71.307 1.00 91.96 C +ATOM 9683 O TYR F 21 69.763 -34.949 71.682 1.00 92.81 O +ATOM 9684 CB TYR F 21 67.138 -36.862 70.897 1.00 83.18 C +ATOM 9685 CG TYR F 21 66.587 -36.002 71.998 1.00111.71 C +ATOM 9686 CD1 TYR F 21 65.902 -34.805 71.683 1.00188.56 C +ATOM 9687 CD2 TYR F 21 66.771 -36.321 73.328 1.00 74.61 C +ATOM 9688 CE1 TYR F 21 65.403 -33.972 72.665 1.00163.07 C +ATOM 9689 CE2 TYR F 21 66.273 -35.488 74.313 1.00109.29 C +ATOM 9690 CZ TYR F 21 65.574 -34.321 73.970 1.00141.44 C +ATOM 9691 OH TYR F 21 65.071 -33.460 74.919 1.00138.92 O +ATOM 9692 N LYS F 22 70.017 -37.178 71.797 1.00135.10 N +ATOM 9693 CA LYS F 22 71.041 -37.131 72.841 1.00126.67 C +ATOM 9694 C LYS F 22 72.284 -36.347 72.427 1.00108.14 C +ATOM 9695 O LYS F 22 72.821 -35.572 73.219 1.00116.37 O +ATOM 9696 CB LYS F 22 71.465 -38.547 73.222 1.00148.56 C +ATOM 9697 CG LYS F 22 70.609 -39.157 74.309 1.00149.61 C +ATOM 9698 CD LYS F 22 71.071 -38.669 75.690 1.00121.78 C +ATOM 9699 CE LYS F 22 71.904 -39.754 76.377 1.00131.04 C +ATOM 9700 NZ LYS F 22 71.087 -40.965 76.681 1.00160.27 N +ATOM 9701 N ASP F 23 72.718 -36.541 71.182 1.00106.65 N +ATOM 9702 CA ASP F 23 73.781 -35.724 70.591 1.00114.87 C +ATOM 9703 C ASP F 23 73.395 -34.243 70.486 1.00139.47 C +ATOM 9704 O ASP F 23 74.157 -33.350 70.873 1.00141.02 O +ATOM 9705 CB ASP F 23 74.127 -36.232 69.191 1.00 96.31 C +ATOM 9706 CG ASP F 23 74.727 -37.586 69.223 1.00106.32 C +ATOM 9707 OD1 ASP F 23 75.575 -37.818 70.118 1.00144.14 O +ATOM 9708 OD2 ASP F 23 74.403 -38.404 68.344 1.00 94.74 O +ATOM 9709 N LEU F 24 72.180 -33.997 70.004 1.00160.76 N +ATOM 9710 CA LEU F 24 71.683 -32.642 69.754 1.00150.18 C +ATOM 9711 C LEU F 24 71.575 -31.802 71.041 1.00139.90 C +ATOM 9712 O LEU F 24 71.800 -30.589 71.028 1.00136.45 O +ATOM 9713 CB LEU F 24 70.308 -32.724 69.060 1.00152.74 C +ATOM 9714 CG LEU F 24 69.605 -31.416 68.685 1.00132.81 C +ATOM 9715 CD1 LEU F 24 70.095 -30.916 67.326 1.00150.02 C +ATOM 9716 CD2 LEU F 24 68.096 -31.604 68.681 1.00 97.00 C +ATOM 9717 N THR F 25 71.185 -32.450 72.136 1.00137.95 N +ATOM 9718 CA THR F 25 70.971 -31.761 73.412 1.00137.76 C +ATOM 9719 C THR F 25 72.287 -31.401 74.080 1.00112.20 C +ATOM 9720 O THR F 25 72.465 -30.279 74.545 1.00 72.51 O +ATOM 9721 CB THR F 25 70.115 -32.620 74.376 1.00194.63 C +ATOM 9722 OG1 THR F 25 70.584 -33.978 74.380 1.00260.10 O +ATOM 9723 CG2 THR F 25 68.656 -32.607 73.939 1.00218.62 C +ATOM 9724 N HIS F 26 73.204 -32.374 74.131 1.00146.62 N +ATOM 9725 CA HIS F 26 74.500 -32.223 74.822 1.00127.45 C +ATOM 9726 C HIS F 26 75.544 -31.519 73.941 1.00 89.33 C +ATOM 9727 O HIS F 26 76.701 -31.893 73.917 1.00 76.08 O +ATOM 9728 CB HIS F 26 74.999 -33.607 75.316 1.00128.73 C +ATOM 9729 CG HIS F 26 74.120 -34.240 76.366 1.00145.17 C +ATOM 9730 ND1 HIS F 26 72.859 -34.730 76.093 1.00168.41 N +ATOM 9731 CD2 HIS F 26 74.321 -34.457 77.690 1.00158.21 C +ATOM 9732 CE1 HIS F 26 72.317 -35.204 77.203 1.00144.79 C +ATOM 9733 NE2 HIS F 26 73.186 -35.060 78.184 1.00141.64 N +ATOM 9734 N LEU F 27 75.090 -30.596 73.108 1.00 89.34 N +ATOM 9735 CA LEU F 27 75.995 -29.850 72.251 1.00103.82 C +ATOM 9736 C LEU F 27 76.479 -28.624 73.018 1.00108.93 C +ATOM 9737 O LEU F 27 75.680 -27.939 73.648 1.00 81.14 O +ATOM 9738 CB LEU F 27 75.304 -29.415 70.947 1.00122.45 C +ATOM 9739 CG LEU F 27 75.379 -30.406 69.779 1.00130.52 C +ATOM 9740 CD1 LEU F 27 74.412 -30.020 68.668 1.00136.85 C +ATOM 9741 CD2 LEU F 27 76.798 -30.502 69.233 1.00134.87 C +ATOM 9742 N PRO F 28 77.791 -28.323 72.936 1.00125.16 N +ATOM 9743 CA PRO F 28 78.385 -27.171 73.640 1.00106.90 C +ATOM 9744 C PRO F 28 77.765 -25.874 73.192 1.00143.14 C +ATOM 9745 O PRO F 28 77.662 -25.638 71.996 1.00219.12 O +ATOM 9746 CB PRO F 28 79.843 -27.218 73.224 1.00 94.24 C +ATOM 9747 CG PRO F 28 79.856 -27.989 71.935 1.00 99.94 C +ATOM 9748 CD PRO F 28 78.767 -29.007 72.063 1.00119.05 C +ATOM 9749 N ALA F 29 77.324 -25.052 74.135 1.00170.24 N +ATOM 9750 CA ALA F 29 76.471 -23.902 73.811 1.00165.15 C +ATOM 9751 C ALA F 29 77.262 -22.761 73.132 1.00162.81 C +ATOM 9752 O ALA F 29 78.473 -22.594 73.363 1.00132.43 O +ATOM 9753 CB ALA F 29 75.765 -23.397 75.061 1.00164.94 C +ATOM 9754 N PRO F 30 76.592 -22.013 72.234 1.00146.21 N +ATOM 9755 CA PRO F 30 77.199 -20.859 71.546 1.00127.93 C +ATOM 9756 C PRO F 30 77.266 -19.628 72.450 1.00100.86 C +ATOM 9757 O PRO F 30 76.749 -19.675 73.577 1.00115.21 O +ATOM 9758 CB PRO F 30 76.219 -20.590 70.413 1.00128.43 C +ATOM 9759 CG PRO F 30 74.900 -21.056 70.938 1.00113.28 C +ATOM 9760 CD PRO F 30 75.179 -22.208 71.857 1.00121.71 C +ATOM 9761 N THR F 31 77.836 -18.528 71.947 1.00 75.87 N +ATOM 9762 CA THR F 31 78.009 -17.298 72.754 1.00 94.85 C +ATOM 9763 C THR F 31 76.685 -16.606 73.020 1.00107.74 C +ATOM 9764 O THR F 31 76.523 -15.921 74.029 1.00142.22 O +ATOM 9765 CB THR F 31 78.981 -16.272 72.113 1.00106.23 C +ATOM 9766 OG1 THR F 31 78.609 -16.015 70.758 1.00115.57 O +ATOM 9767 CG2 THR F 31 80.425 -16.778 72.151 1.00112.96 C +ATOM 9768 N GLY F 32 75.722 -16.823 72.132 1.00133.93 N +ATOM 9769 CA GLY F 32 74.326 -16.476 72.397 1.00137.36 C +ATOM 9770 C GLY F 32 73.457 -17.356 71.531 1.00118.03 C +ATOM 9771 O GLY F 32 73.905 -17.801 70.473 1.00130.54 O +ATOM 9772 N LYS F 33 72.210 -17.582 71.933 1.00103.19 N +ATOM 9773 CA LYS F 33 71.274 -18.274 71.042 1.00106.30 C +ATOM 9774 C LYS F 33 70.951 -17.449 69.768 1.00127.04 C +ATOM 9775 O LYS F 33 70.998 -16.213 69.792 1.00104.98 O +ATOM 9776 CB LYS F 33 69.985 -18.644 71.756 1.00 74.73 C +ATOM 9777 CG LYS F 33 70.038 -19.968 72.451 1.00 69.74 C +ATOM 9778 CD LYS F 33 68.804 -20.178 73.300 1.00 73.36 C +ATOM 9779 CE LYS F 33 69.090 -21.130 74.438 1.00 82.54 C +ATOM 9780 NZ LYS F 33 67.954 -21.234 75.373 1.00 92.50 N +ATOM 9781 N ILE F 34 70.675 -18.137 68.659 1.00131.41 N +ATOM 9782 CA ILE F 34 70.450 -17.471 67.382 1.00123.05 C +ATOM 9783 C ILE F 34 68.947 -17.540 67.072 1.00137.70 C +ATOM 9784 O ILE F 34 68.262 -18.501 67.461 1.00 99.99 O +ATOM 9785 CB ILE F 34 71.343 -18.073 66.265 1.00119.19 C +ATOM 9786 CG1 ILE F 34 72.817 -17.777 66.542 1.00113.13 C +ATOM 9787 CG2 ILE F 34 71.013 -17.500 64.896 1.00141.86 C +ATOM 9788 CD1 ILE F 34 73.654 -19.022 66.743 1.00126.85 C +ATOM 9789 N PHE F 35 68.429 -16.446 66.501 1.00133.65 N +ATOM 9790 CA PHE F 35 67.014 -16.297 66.164 1.00122.86 C +ATOM 9791 C PHE F 35 66.700 -16.912 64.809 1.00124.28 C +ATOM 9792 O PHE F 35 67.354 -16.581 63.842 1.00115.86 O +ATOM 9793 CB PHE F 35 66.676 -14.823 66.071 1.00 96.70 C +ATOM 9794 CG PHE F 35 66.327 -14.192 67.381 1.00107.10 C +ATOM 9795 CD1 PHE F 35 65.437 -14.810 68.276 1.00124.91 C +ATOM 9796 CD2 PHE F 35 66.755 -12.919 67.654 1.00112.44 C +ATOM 9797 CE1 PHE F 35 65.079 -14.204 69.467 1.00103.01 C +ATOM 9798 CE2 PHE F 35 66.364 -12.289 68.824 1.00126.51 C +ATOM 9799 CZ PHE F 35 65.530 -12.934 69.732 1.00116.52 C +ATOM 9800 N VAL F 36 65.731 -17.828 64.750 1.00118.32 N +ATOM 9801 CA VAL F 36 65.518 -18.614 63.539 1.00 97.86 C +ATOM 9802 C VAL F 36 64.058 -18.714 63.179 1.00 73.79 C +ATOM 9803 O VAL F 36 63.196 -18.659 64.038 1.00 65.97 O +ATOM 9804 CB VAL F 36 66.076 -20.053 63.657 1.00110.86 C +ATOM 9805 CG1 VAL F 36 65.174 -20.937 64.525 1.00 92.16 C +ATOM 9806 CG2 VAL F 36 66.237 -20.645 62.275 1.00104.44 C +ATOM 9807 N SER F 37 63.798 -18.844 61.891 1.00 69.43 N +ATOM 9808 CA SER F 37 62.444 -18.879 61.401 1.00 79.00 C +ATOM 9809 C SER F 37 62.308 -20.127 60.594 1.00 72.19 C +ATOM 9810 O SER F 37 63.091 -20.362 59.686 1.00 42.16 O +ATOM 9811 CB SER F 37 62.154 -17.668 60.497 1.00 99.49 C +ATOM 9812 OG SER F 37 61.977 -16.467 61.236 1.00153.15 O +ATOM 9813 N VAL F 38 61.246 -20.887 60.836 1.00105.18 N +ATOM 9814 CA VAL F 38 60.859 -21.955 59.884 1.00111.60 C +ATOM 9815 C VAL F 38 59.431 -21.763 59.360 1.00 91.94 C +ATOM 9816 O VAL F 38 58.488 -21.718 60.159 1.00 93.15 O +ATOM 9817 CB VAL F 38 60.906 -23.345 60.536 1.00117.77 C +ATOM 9818 CG1 VAL F 38 60.480 -24.387 59.532 1.00107.35 C +ATOM 9819 CG2 VAL F 38 62.297 -23.650 61.074 1.00156.72 C +ATOM 9820 N TYR F 39 59.301 -21.586 58.041 1.00 74.23 N +ATOM 9821 CA TYR F 39 58.013 -21.271 57.406 1.00 82.72 C +ATOM 9822 C TYR F 39 57.346 -22.582 56.992 1.00 84.25 C +ATOM 9823 O TYR F 39 56.220 -22.872 57.396 1.00 92.20 O +ATOM 9824 CB TYR F 39 58.188 -20.303 56.197 1.00 79.20 C +ATOM 9825 CG TYR F 39 58.188 -18.798 56.560 1.00 72.86 C +ATOM 9826 CD1 TYR F 39 59.277 -18.214 57.183 1.00 73.16 C +ATOM 9827 CD2 TYR F 39 57.054 -18.005 56.385 1.00 78.20 C +ATOM 9828 CE1 TYR F 39 59.250 -16.880 57.605 1.00 70.04 C +ATOM 9829 CE2 TYR F 39 57.011 -16.684 56.819 1.00 66.12 C +ATOM 9830 CZ TYR F 39 58.121 -16.110 57.424 1.00 62.28 C +ATOM 9831 OH TYR F 39 58.133 -14.759 57.759 1.00 34.82 O +ATOM 9832 N ASN F 40 58.078 -23.428 56.271 1.00 84.92 N +ATOM 9833 CA ASN F 40 57.525 -24.719 55.841 1.00 84.52 C +ATOM 9834 C ASN F 40 58.558 -25.710 55.271 1.00 90.46 C +ATOM 9835 O ASN F 40 59.386 -25.339 54.432 1.00131.25 O +ATOM 9836 CB ASN F 40 56.453 -24.468 54.787 1.00 89.33 C +ATOM 9837 CG ASN F 40 55.517 -25.639 54.624 1.00111.35 C +ATOM 9838 OD1 ASN F 40 54.846 -26.076 55.580 1.00158.82 O +ATOM 9839 ND2 ASN F 40 55.480 -26.177 53.416 1.00 96.99 N +ATOM 9840 N ILE F 41 58.505 -26.963 55.723 1.00 81.12 N +ATOM 9841 CA ILE F 41 59.268 -28.053 55.090 1.00 92.77 C +ATOM 9842 C ILE F 41 58.342 -29.121 54.493 1.00 79.56 C +ATOM 9843 O ILE F 41 57.521 -29.687 55.220 1.00113.12 O +ATOM 9844 CB ILE F 41 60.195 -28.742 56.093 1.00 99.76 C +ATOM 9845 CG1 ILE F 41 61.481 -27.934 56.297 1.00114.35 C +ATOM 9846 CG2 ILE F 41 60.611 -30.101 55.555 1.00114.94 C +ATOM 9847 CD1 ILE F 41 61.328 -26.647 57.072 1.00135.45 C +ATOM 9848 N GLN F 42 58.384 -29.304 53.172 1.00 62.01 N +ATOM 9849 CA GLN F 42 57.303 -30.007 52.464 1.00 78.43 C +ATOM 9850 C GLN F 42 57.607 -31.459 52.321 1.00 60.94 C +ATOM 9851 O GLN F 42 58.751 -31.847 52.377 1.00 60.83 O +ATOM 9852 CB GLN F 42 57.049 -29.441 51.057 1.00109.83 C +ATOM 9853 CG GLN F 42 56.480 -28.028 51.021 1.00123.94 C +ATOM 9854 CD GLN F 42 57.407 -27.050 50.319 1.00135.43 C +ATOM 9855 OE1 GLN F 42 57.362 -26.908 49.087 1.00142.31 O +ATOM 9856 NE2 GLN F 42 58.301 -26.411 51.087 1.00113.14 N +ATOM 9857 N ASP F 43 56.549 -32.262 52.177 1.00 69.88 N +ATOM 9858 CA ASP F 43 56.666 -33.673 51.829 1.00 65.88 C +ATOM 9859 C ASP F 43 56.940 -33.834 50.333 1.00 65.48 C +ATOM 9860 O ASP F 43 56.068 -34.323 49.598 1.00 74.55 O +ATOM 9861 CB ASP F 43 55.386 -34.420 52.221 1.00 69.51 C +ATOM 9862 CG ASP F 43 55.524 -35.946 52.066 1.00 84.18 C +ATOM 9863 OD1 ASP F 43 56.519 -36.493 52.565 1.00 77.29 O +ATOM 9864 OD2 ASP F 43 54.649 -36.603 51.448 1.00 98.08 O +ATOM 9865 N GLU F 44 58.094 -33.336 49.872 1.00 57.35 N +ATOM 9866 CA GLU F 44 58.421 -33.310 48.443 1.00 59.87 C +ATOM 9867 C GLU F 44 58.693 -34.735 47.930 1.00 58.96 C +ATOM 9868 O GLU F 44 59.174 -34.915 46.789 1.00 61.53 O +ATOM 9869 CB GLU F 44 59.619 -32.392 48.158 1.00 60.21 C +ATOM 9870 CG GLU F 44 59.285 -30.924 47.896 1.00 83.74 C +ATOM 9871 CD GLU F 44 60.521 -30.021 47.661 1.00127.96 C +ATOM 9872 OE1 GLU F 44 61.459 -30.386 46.899 1.00175.96 O +ATOM 9873 OE2 GLU F 44 60.553 -28.886 48.201 1.00158.90 O +ATOM 9874 N THR F 45 58.281 -35.738 48.714 1.00 57.17 N +ATOM 9875 CA THR F 45 58.603 -37.133 48.415 1.00 71.52 C +ATOM 9876 C THR F 45 57.814 -37.728 47.248 1.00 89.01 C +ATOM 9877 O THR F 45 58.358 -38.493 46.444 1.00 70.33 O +ATOM 9878 CB THR F 45 58.474 -38.021 49.664 1.00 90.46 C +ATOM 9879 OG1 THR F 45 59.098 -39.289 49.429 1.00163.83 O +ATOM 9880 CG2 THR F 45 57.012 -38.279 50.074 1.00 76.80 C +ATOM 9881 N GLY F 46 56.513 -37.433 47.172 1.00102.44 N +ATOM 9882 CA GLY F 46 55.673 -37.869 46.020 1.00 82.72 C +ATOM 9883 C GLY F 46 55.021 -39.249 46.183 1.00 62.70 C +ATOM 9884 O GLY F 46 54.607 -39.905 45.236 1.00 40.42 O +ATOM 9885 N GLN F 47 54.862 -39.672 47.413 1.00 61.59 N +ATOM 9886 CA GLN F 47 54.691 -41.061 47.612 1.00 67.59 C +ATOM 9887 C GLN F 47 53.588 -41.333 48.591 1.00 72.62 C +ATOM 9888 O GLN F 47 53.451 -40.657 49.612 1.00 52.14 O +ATOM 9889 CB GLN F 47 55.995 -41.667 48.054 1.00 71.77 C +ATOM 9890 CG GLN F 47 57.083 -41.661 46.961 1.00 73.88 C +ATOM 9891 CD GLN F 47 56.626 -42.235 45.661 1.00 61.07 C +ATOM 9892 OE1 GLN F 47 56.402 -43.434 45.557 1.00 82.54 O +ATOM 9893 NE2 GLN F 47 56.436 -41.397 44.686 1.00 62.78 N +ATOM 9894 N PHE F 48 52.784 -42.323 48.216 1.00 91.79 N +ATOM 9895 CA PHE F 48 51.654 -42.785 49.013 1.00 84.14 C +ATOM 9896 C PHE F 48 51.733 -44.281 49.243 1.00 94.90 C +ATOM 9897 O PHE F 48 52.582 -44.996 48.660 1.00 99.77 O +ATOM 9898 CB PHE F 48 50.347 -42.529 48.298 1.00 84.83 C +ATOM 9899 CG PHE F 48 50.042 -41.104 48.128 1.00 82.71 C +ATOM 9900 CD1 PHE F 48 50.709 -40.377 47.144 1.00 79.31 C +ATOM 9901 CD2 PHE F 48 49.090 -40.495 48.927 1.00 58.65 C +ATOM 9902 CE1 PHE F 48 50.495 -39.035 47.022 1.00 76.02 C +ATOM 9903 CE2 PHE F 48 48.838 -39.166 48.786 1.00 52.53 C +ATOM 9904 CZ PHE F 48 49.568 -38.427 47.857 1.00 72.81 C +ATOM 9905 N LYS F 49 50.888 -44.744 50.158 1.00 94.75 N +ATOM 9906 CA LYS F 49 50.981 -46.118 50.643 1.00112.67 C +ATOM 9907 C LYS F 49 50.269 -46.981 49.651 1.00118.89 C +ATOM 9908 O LYS F 49 49.313 -46.528 49.016 1.00155.36 O +ATOM 9909 CB LYS F 49 50.382 -46.273 52.048 1.00113.91 C +ATOM 9910 CG LYS F 49 51.227 -45.574 53.119 1.00120.19 C +ATOM 9911 CD LYS F 49 50.853 -45.831 54.567 1.00119.63 C +ATOM 9912 CE LYS F 49 51.923 -45.163 55.436 1.00125.03 C +ATOM 9913 NZ LYS F 49 51.756 -45.341 56.903 1.00156.56 N +ATOM 9914 N PRO F 50 50.773 -48.210 49.467 1.00110.08 N +ATOM 9915 CA PRO F 50 50.176 -49.131 48.523 1.00113.99 C +ATOM 9916 C PRO F 50 48.917 -49.800 49.090 1.00103.48 C +ATOM 9917 O PRO F 50 48.652 -49.734 50.307 1.00 57.60 O +ATOM 9918 CB PRO F 50 51.298 -50.156 48.290 1.00121.22 C +ATOM 9919 CG PRO F 50 52.097 -50.144 49.551 1.00 98.54 C +ATOM 9920 CD PRO F 50 52.018 -48.741 50.059 1.00 97.30 C +ATOM 9921 N TYR F 51 48.182 -50.474 48.210 1.00 91.58 N +ATOM 9922 CA TYR F 51 47.094 -51.315 48.647 1.00 91.33 C +ATOM 9923 C TYR F 51 47.560 -52.250 49.748 1.00 98.57 C +ATOM 9924 O TYR F 51 48.657 -52.820 49.651 1.00129.89 O +ATOM 9925 CB TYR F 51 46.551 -52.138 47.487 1.00 95.35 C +ATOM 9926 CG TYR F 51 45.207 -52.750 47.823 1.00103.08 C +ATOM 9927 CD1 TYR F 51 44.044 -52.029 47.634 1.00105.45 C +ATOM 9928 CD2 TYR F 51 45.100 -54.035 48.334 1.00109.65 C +ATOM 9929 CE1 TYR F 51 42.812 -52.560 47.935 1.00 96.04 C +ATOM 9930 CE2 TYR F 51 43.855 -54.588 48.612 1.00101.66 C +ATOM 9931 CZ TYR F 51 42.724 -53.818 48.432 1.00 92.45 C +ATOM 9932 OH TYR F 51 41.470 -54.293 48.710 1.00127.80 O +ATOM 9933 N PRO F 52 46.744 -52.423 50.809 1.00107.76 N +ATOM 9934 CA PRO F 52 45.379 -51.940 51.031 1.00106.58 C +ATOM 9935 C PRO F 52 45.214 -50.591 51.718 1.00134.32 C +ATOM 9936 O PRO F 52 44.128 -50.328 52.252 1.00146.44 O +ATOM 9937 CB PRO F 52 44.788 -53.028 51.920 1.00108.01 C +ATOM 9938 CG PRO F 52 45.949 -53.463 52.768 1.00120.00 C +ATOM 9939 CD PRO F 52 47.173 -53.345 51.886 1.00122.78 C +ATOM 9940 N ALA F 53 46.256 -49.752 51.757 1.00143.90 N +ATOM 9941 CA ALA F 53 46.119 -48.432 52.396 1.00152.93 C +ATOM 9942 C ALA F 53 45.093 -47.626 51.625 1.00163.78 C +ATOM 9943 O ALA F 53 44.810 -47.909 50.458 1.00158.93 O +ATOM 9944 CB ALA F 53 47.452 -47.683 52.468 1.00122.09 C +ATOM 9945 N SER F 54 44.545 -46.598 52.263 1.00192.31 N +ATOM 9946 CA SER F 54 43.783 -45.626 51.499 1.00172.02 C +ATOM 9947 C SER F 54 44.675 -45.052 50.404 1.00165.45 C +ATOM 9948 O SER F 54 45.894 -44.806 50.595 1.00258.48 O +ATOM 9949 CB SER F 54 43.246 -44.497 52.376 1.00187.88 C +ATOM 9950 OG SER F 54 42.943 -43.333 51.616 1.00164.78 O +ATOM 9951 N ASN F 55 44.063 -44.840 49.248 1.00105.87 N +ATOM 9952 CA ASN F 55 44.741 -44.226 48.120 1.00 81.29 C +ATOM 9953 C ASN F 55 45.457 -42.935 48.518 1.00 85.88 C +ATOM 9954 O ASN F 55 46.521 -42.558 47.963 1.00111.63 O +ATOM 9955 CB ASN F 55 43.711 -43.940 47.054 1.00 59.63 C +ATOM 9956 CG ASN F 55 44.325 -43.752 45.710 1.00 76.97 C +ATOM 9957 OD1 ASN F 55 45.506 -44.038 45.462 1.00113.53 O +ATOM 9958 ND2 ASN F 55 43.532 -43.251 44.818 1.00 79.60 N +ATOM 9959 N PHE F 56 44.911 -42.291 49.554 1.00 83.71 N +ATOM 9960 CA PHE F 56 45.326 -40.952 49.967 1.00 87.76 C +ATOM 9961 C PHE F 56 46.292 -40.938 51.142 1.00 99.55 C +ATOM 9962 O PHE F 56 46.688 -39.876 51.621 1.00118.24 O +ATOM 9963 CB PHE F 56 44.098 -40.137 50.366 1.00 79.32 C +ATOM 9964 CG PHE F 56 43.051 -40.059 49.282 1.00 71.06 C +ATOM 9965 CD1 PHE F 56 43.327 -39.493 48.030 1.00 74.82 C +ATOM 9966 CD2 PHE F 56 41.826 -40.586 49.487 1.00 74.17 C +ATOM 9967 CE1 PHE F 56 42.397 -39.516 47.001 1.00 58.80 C +ATOM 9968 CE2 PHE F 56 40.852 -40.504 48.497 1.00 77.99 C +ATOM 9969 CZ PHE F 56 41.144 -39.987 47.242 1.00 54.94 C +ATOM 9970 N SER F 57 46.632 -42.102 51.665 1.00120.93 N +ATOM 9971 CA SER F 57 47.577 -42.160 52.783 1.00105.31 C +ATOM 9972 C SER F 57 48.999 -41.908 52.272 1.00 99.29 C +ATOM 9973 O SER F 57 49.561 -42.662 51.469 1.00 64.58 O +ATOM 9974 CB SER F 57 47.484 -43.510 53.498 1.00132.93 C +ATOM 9975 OG SER F 57 46.299 -43.577 54.263 1.00153.63 O +ATOM 9976 N THR F 58 49.592 -40.825 52.738 1.00 98.40 N +ATOM 9977 CA THR F 58 50.939 -40.472 52.311 1.00 94.45 C +ATOM 9978 C THR F 58 51.920 -41.439 52.899 1.00 84.20 C +ATOM 9979 O THR F 58 51.755 -41.922 54.023 1.00 71.18 O +ATOM 9980 CB THR F 58 51.300 -39.050 52.773 1.00102.59 C +ATOM 9981 OG1 THR F 58 51.232 -38.958 54.204 1.00136.14 O +ATOM 9982 CG2 THR F 58 50.327 -38.076 52.200 1.00127.49 C +ATOM 9983 N ALA F 59 53.050 -41.593 52.250 1.00108.20 N +ATOM 9984 CA ALA F 59 54.041 -42.492 52.817 1.00143.09 C +ATOM 9985 C ALA F 59 54.820 -41.870 53.998 1.00159.93 C +ATOM 9986 O ALA F 59 55.372 -42.588 54.837 1.00 90.77 O +ATOM 9987 CB ALA F 59 54.999 -42.928 51.754 1.00122.99 C +ATOM 9988 N VAL F 60 54.803 -40.534 54.082 1.00147.37 N +ATOM 9989 CA VAL F 60 55.575 -39.789 55.074 1.00113.34 C +ATOM 9990 C VAL F 60 54.679 -38.755 55.762 1.00 90.28 C +ATOM 9991 O VAL F 60 53.848 -38.136 55.108 1.00 96.57 O +ATOM 9992 CB VAL F 60 56.733 -39.072 54.372 1.00114.71 C +ATOM 9993 CG1 VAL F 60 57.575 -38.257 55.358 1.00129.58 C +ATOM 9994 CG2 VAL F 60 57.590 -40.078 53.622 1.00105.35 C +ATOM 9995 N PRO F 61 54.839 -38.558 57.087 1.00109.42 N +ATOM 9996 CA PRO F 61 54.006 -37.571 57.767 1.00138.55 C +ATOM 9997 C PRO F 61 54.291 -36.150 57.304 1.00159.10 C +ATOM 9998 O PRO F 61 55.436 -35.817 56.981 1.00117.41 O +ATOM 9999 CB PRO F 61 54.384 -37.728 59.245 1.00136.90 C +ATOM 10000 CG PRO F 61 55.716 -38.369 59.229 1.00138.27 C +ATOM 10001 CD PRO F 61 55.700 -39.278 58.036 1.00139.48 C +ATOM 10002 N GLN F 62 53.233 -35.338 57.254 1.00172.95 N +ATOM 10003 CA GLN F 62 53.307 -33.989 56.694 1.00145.87 C +ATOM 10004 C GLN F 62 53.714 -33.001 57.760 1.00157.44 C +ATOM 10005 O GLN F 62 53.253 -31.872 57.768 1.00 85.79 O +ATOM 10006 CB GLN F 62 51.951 -33.575 56.124 1.00132.46 C +ATOM 10007 CG GLN F 62 51.354 -34.573 55.157 1.00113.24 C +ATOM 10008 CD GLN F 62 52.312 -34.812 54.012 1.00 94.20 C +ATOM 10009 OE1 GLN F 62 52.338 -34.055 53.059 1.00102.59 O +ATOM 10010 NE2 GLN F 62 53.017 -35.916 54.052 1.00123.38 N +ATOM 10011 N SER F 63 54.560 -33.450 58.680 1.00174.33 N +ATOM 10012 CA SER F 63 54.729 -32.772 59.956 1.00153.52 C +ATOM 10013 C SER F 63 56.173 -32.288 60.152 1.00130.53 C +ATOM 10014 O SER F 63 56.552 -31.864 61.251 1.00136.51 O +ATOM 10015 CB SER F 63 54.273 -33.699 61.103 1.00132.20 C +ATOM 10016 OG SER F 63 55.049 -34.891 61.204 1.00106.92 O +ATOM 10017 N ALA F 64 56.973 -32.388 59.088 1.00 78.10 N +ATOM 10018 CA ALA F 64 58.399 -32.149 59.164 1.00 71.61 C +ATOM 10019 C ALA F 64 58.753 -30.756 59.707 1.00 84.15 C +ATOM 10020 O ALA F 64 59.699 -30.613 60.522 1.00114.92 O +ATOM 10021 CB ALA F 64 58.999 -32.346 57.794 1.00 57.57 C +ATOM 10022 N THR F 65 57.961 -29.768 59.299 1.00 79.60 N +ATOM 10023 CA THR F 65 58.124 -28.381 59.709 1.00 82.64 C +ATOM 10024 C THR F 65 58.181 -28.254 61.249 1.00 84.30 C +ATOM 10025 O THR F 65 59.120 -27.652 61.816 1.00 77.96 O +ATOM 10026 CB THR F 65 56.969 -27.521 59.136 1.00 98.31 C +ATOM 10027 OG1 THR F 65 57.018 -26.173 59.671 1.00183.62 O +ATOM 10028 CG2 THR F 65 55.660 -28.212 59.509 1.00 79.61 C +ATOM 10029 N ALA F 66 57.238 -28.891 61.953 1.00 85.33 N +ATOM 10030 CA ALA F 66 57.179 -28.784 63.429 1.00 94.50 C +ATOM 10031 C ALA F 66 58.305 -29.571 64.127 1.00 94.11 C +ATOM 10032 O ALA F 66 58.867 -29.125 65.136 1.00 85.19 O +ATOM 10033 CB ALA F 66 55.837 -29.253 63.927 1.00 94.30 C +ATOM 10034 N MET F 67 58.703 -30.678 63.507 1.00 80.80 N +ATOM 10035 CA MET F 67 59.842 -31.439 63.988 1.00 77.97 C +ATOM 10036 C MET F 67 61.123 -30.601 63.931 1.00 53.46 C +ATOM 10037 O MET F 67 61.962 -30.673 64.836 1.00 67.80 O +ATOM 10038 CB MET F 67 60.017 -32.746 63.170 1.00 93.34 C +ATOM 10039 CG MET F 67 58.931 -33.806 63.386 1.00100.00 C +ATOM 10040 SD MET F 67 59.053 -35.141 62.150 1.00 69.37 S +ATOM 10041 CE MET F 67 57.791 -36.263 62.752 1.00100.17 C +ATOM 10042 N LEU F 68 61.344 -29.950 62.801 1.00 38.72 N +ATOM 10043 CA LEU F 68 62.531 -29.157 62.643 1.00 41.67 C +ATOM 10044 C LEU F 68 62.568 -28.044 63.659 1.00 47.79 C +ATOM 10045 O LEU F 68 63.602 -27.764 64.234 1.00 77.29 O +ATOM 10046 CB LEU F 68 62.603 -28.531 61.261 1.00 58.86 C +ATOM 10047 CG LEU F 68 63.713 -27.447 61.109 1.00 57.45 C +ATOM 10048 CD1 LEU F 68 65.069 -28.118 61.215 1.00 75.78 C +ATOM 10049 CD2 LEU F 68 63.618 -26.704 59.797 1.00 57.05 C +ATOM 10050 N VAL F 69 61.448 -27.355 63.861 1.00 71.71 N +ATOM 10051 CA VAL F 69 61.377 -26.239 64.841 1.00 69.24 C +ATOM 10052 C VAL F 69 61.722 -26.773 66.229 1.00 84.17 C +ATOM 10053 O VAL F 69 62.504 -26.168 66.963 1.00 76.11 O +ATOM 10054 CB VAL F 69 59.978 -25.547 64.901 1.00 54.43 C +ATOM 10055 CG1 VAL F 69 59.937 -24.568 66.041 1.00 41.36 C +ATOM 10056 CG2 VAL F 69 59.639 -24.832 63.585 1.00 57.13 C +ATOM 10057 N THR F 70 61.181 -27.945 66.546 1.00106.99 N +ATOM 10058 CA THR F 70 61.433 -28.582 67.836 1.00116.30 C +ATOM 10059 C THR F 70 62.903 -28.956 68.004 1.00 91.19 C +ATOM 10060 O THR F 70 63.515 -28.689 69.034 1.00105.58 O +ATOM 10061 CB THR F 70 60.550 -29.828 68.007 1.00103.13 C +ATOM 10062 OG1 THR F 70 59.177 -29.436 67.827 1.00151.02 O +ATOM 10063 CG2 THR F 70 60.756 -30.440 69.406 1.00 79.57 C +ATOM 10064 N ALA F 71 63.481 -29.508 66.955 1.00 72.73 N +ATOM 10065 CA ALA F 71 64.887 -29.851 66.983 1.00 74.44 C +ATOM 10066 C ALA F 71 65.734 -28.603 67.178 1.00 61.82 C +ATOM 10067 O ALA F 71 66.747 -28.623 67.890 1.00 78.32 O +ATOM 10068 CB ALA F 71 65.283 -30.619 65.704 1.00 84.52 C +ATOM 10069 N LEU F 72 65.377 -27.547 66.470 1.00 67.05 N +ATOM 10070 CA LEU F 72 66.133 -26.293 66.535 1.00 92.60 C +ATOM 10071 C LEU F 72 66.077 -25.741 67.937 1.00101.65 C +ATOM 10072 O LEU F 72 66.973 -25.002 68.351 1.00108.67 O +ATOM 10073 CB LEU F 72 65.573 -25.249 65.553 1.00 99.16 C +ATOM 10074 CG LEU F 72 65.816 -25.550 64.072 1.00 96.82 C +ATOM 10075 CD1 LEU F 72 64.868 -24.718 63.238 1.00 77.80 C +ATOM 10076 CD2 LEU F 72 67.260 -25.308 63.664 1.00 86.48 C +ATOM 10077 N LYS F 73 65.017 -26.076 68.669 1.00 96.14 N +ATOM 10078 CA LYS F 73 64.888 -25.594 70.050 1.00111.39 C +ATOM 10079 C LYS F 73 65.677 -26.464 71.021 1.00107.55 C +ATOM 10080 O LYS F 73 66.351 -25.943 71.897 1.00126.60 O +ATOM 10081 CB LYS F 73 63.420 -25.521 70.487 1.00 91.87 C +ATOM 10082 CG LYS F 73 63.182 -24.738 71.788 1.00 67.79 C +ATOM 10083 CD LYS F 73 61.696 -24.714 72.166 1.00 65.10 C +ATOM 10084 CE LYS F 73 61.477 -24.613 73.667 1.00 64.52 C +ATOM 10085 NZ LYS F 73 60.838 -23.345 74.088 1.00 56.39 N +ATOM 10086 N ASP F 74 65.552 -27.775 70.877 1.00100.71 N +ATOM 10087 CA ASP F 74 66.170 -28.701 71.802 1.00112.80 C +ATOM 10088 C ASP F 74 67.679 -28.509 71.810 1.00 97.34 C +ATOM 10089 O ASP F 74 68.337 -28.828 72.804 1.00121.69 O +ATOM 10090 CB ASP F 74 65.796 -30.161 71.442 1.00119.87 C +ATOM 10091 CG ASP F 74 64.320 -30.490 71.719 1.00113.78 C +ATOM 10092 OD1 ASP F 74 63.691 -29.869 72.622 1.00131.58 O +ATOM 10093 OD2 ASP F 74 63.778 -31.372 71.018 1.00 87.43 O +ATOM 10094 N SER F 75 68.229 -28.103 70.668 1.00 83.83 N +ATOM 10095 CA SER F 75 69.691 -27.982 70.500 1.00 97.85 C +ATOM 10096 C SER F 75 70.293 -26.954 71.442 1.00 88.99 C +ATOM 10097 O SER F 75 71.483 -26.996 71.734 1.00 74.85 O +ATOM 10098 CB SER F 75 70.049 -27.614 69.051 1.00103.95 C +ATOM 10099 OG SER F 75 69.971 -26.219 68.838 1.00107.44 O +ATOM 10100 N ARG F 76 69.461 -26.005 71.873 1.00 99.39 N +ATOM 10101 CA ARG F 76 69.883 -24.864 72.698 1.00 93.75 C +ATOM 10102 C ARG F 76 70.934 -24.036 71.990 1.00 68.66 C +ATOM 10103 O ARG F 76 71.833 -23.476 72.603 1.00 56.10 O +ATOM 10104 CB ARG F 76 70.418 -25.340 74.033 1.00122.43 C +ATOM 10105 CG ARG F 76 69.414 -26.114 74.872 1.00135.91 C +ATOM 10106 CD ARG F 76 70.044 -26.507 76.206 1.00139.21 C +ATOM 10107 NE ARG F 76 71.080 -27.526 76.030 1.00141.15 N +ATOM 10108 CZ ARG F 76 72.383 -27.284 75.908 1.00124.79 C +ATOM 10109 NH1 ARG F 76 72.863 -26.042 75.943 1.00106.63 N +ATOM 10110 NH2 ARG F 76 73.210 -28.306 75.718 1.00119.50 N +ATOM 10111 N TRP F 77 70.773 -23.931 70.682 1.00 80.22 N +ATOM 10112 CA TRP F 77 71.499 -22.960 69.874 1.00119.87 C +ATOM 10113 C TRP F 77 70.568 -21.838 69.322 1.00121.34 C +ATOM 10114 O TRP F 77 70.994 -20.695 69.120 1.00 83.28 O +ATOM 10115 CB TRP F 77 72.179 -23.703 68.722 1.00120.16 C +ATOM 10116 CG TRP F 77 73.530 -24.158 69.032 1.00118.10 C +ATOM 10117 CD1 TRP F 77 73.876 -25.198 69.825 1.00139.09 C +ATOM 10118 CD2 TRP F 77 74.749 -23.579 68.566 1.00115.06 C +ATOM 10119 NE1 TRP F 77 75.238 -25.308 69.885 1.00163.70 N +ATOM 10120 CE2 TRP F 77 75.797 -24.328 69.108 1.00126.72 C +ATOM 10121 CE3 TRP F 77 75.055 -22.509 67.729 1.00141.99 C +ATOM 10122 CZ2 TRP F 77 77.142 -24.058 68.826 1.00133.11 C +ATOM 10123 CZ3 TRP F 77 76.393 -22.223 67.473 1.00170.74 C +ATOM 10124 CH2 TRP F 77 77.417 -23.000 68.019 1.00141.00 C +ATOM 10125 N PHE F 78 69.317 -22.201 69.037 1.00124.03 N +ATOM 10126 CA PHE F 78 68.374 -21.340 68.332 1.00 92.18 C +ATOM 10127 C PHE F 78 67.119 -21.081 69.163 1.00 97.00 C +ATOM 10128 O PHE F 78 66.598 -21.989 69.836 1.00 80.86 O +ATOM 10129 CB PHE F 78 67.935 -22.008 67.031 1.00102.45 C +ATOM 10130 CG PHE F 78 69.070 -22.384 66.113 1.00 99.44 C +ATOM 10131 CD1 PHE F 78 69.709 -21.415 65.329 1.00 84.10 C +ATOM 10132 CD2 PHE F 78 69.409 -23.723 65.945 1.00 81.32 C +ATOM 10133 CE1 PHE F 78 70.700 -21.767 64.443 1.00 75.03 C +ATOM 10134 CE2 PHE F 78 70.392 -24.079 65.056 1.00 80.26 C +ATOM 10135 CZ PHE F 78 71.060 -23.095 64.325 1.00 78.40 C +ATOM 10136 N ILE F 79 66.598 -19.863 69.039 1.00103.79 N +ATOM 10137 CA ILE F 79 65.230 -19.517 69.451 1.00106.95 C +ATOM 10138 C ILE F 79 64.352 -19.506 68.217 1.00 86.76 C +ATOM 10139 O ILE F 79 64.728 -18.882 67.207 1.00 94.77 O +ATOM 10140 CB ILE F 79 65.169 -18.100 70.030 1.00126.10 C +ATOM 10141 CG1 ILE F 79 66.262 -17.883 71.076 1.00146.02 C +ATOM 10142 CG2 ILE F 79 63.803 -17.838 70.635 1.00150.33 C +ATOM 10143 CD1 ILE F 79 66.628 -16.422 71.287 1.00116.82 C +ATOM 10144 N PRO F 80 63.299 -20.326 68.228 1.00 87.57 N +ATOM 10145 CA PRO F 80 62.552 -20.319 67.009 1.00107.60 C +ATOM 10146 C PRO F 80 61.493 -19.291 67.148 1.00 78.78 C +ATOM 10147 O PRO F 80 60.804 -19.254 68.153 1.00 79.11 O +ATOM 10148 CB PRO F 80 61.972 -21.745 66.932 1.00131.93 C +ATOM 10149 CG PRO F 80 62.926 -22.570 67.713 1.00120.59 C +ATOM 10150 CD PRO F 80 63.258 -21.655 68.861 1.00108.64 C +ATOM 10151 N LEU F 81 61.310 -18.533 66.094 1.00 59.07 N +ATOM 10152 CA LEU F 81 60.208 -17.680 66.009 1.00 77.53 C +ATOM 10153 C LEU F 81 59.072 -18.399 65.280 1.00 91.00 C +ATOM 10154 O LEU F 81 59.286 -19.086 64.271 1.00 65.96 O +ATOM 10155 CB LEU F 81 60.635 -16.385 65.324 1.00110.11 C +ATOM 10156 CG LEU F 81 61.848 -15.771 66.030 1.00107.97 C +ATOM 10157 CD1 LEU F 81 62.317 -14.582 65.221 1.00112.31 C +ATOM 10158 CD2 LEU F 81 61.488 -15.359 67.441 1.00 91.32 C +ATOM 10159 N GLU F 82 57.852 -18.160 65.784 1.00113.90 N +ATOM 10160 CA GLU F 82 56.641 -18.754 65.241 1.00 77.01 C +ATOM 10161 C GLU F 82 56.223 -18.052 63.932 1.00 97.37 C +ATOM 10162 O GLU F 82 55.664 -16.923 63.930 1.00110.12 O +ATOM 10163 CB GLU F 82 55.508 -18.760 66.273 1.00 56.04 C +ATOM 10164 CG GLU F 82 54.220 -19.403 65.781 1.00 75.43 C +ATOM 10165 CD GLU F 82 54.288 -20.942 65.591 1.00 77.52 C +ATOM 10166 OE1 GLU F 82 55.198 -21.469 64.913 1.00 71.87 O +ATOM 10167 OE2 GLU F 82 53.319 -21.626 65.989 1.00 72.47 O +ATOM 10168 N ARG F 83 56.426 -18.775 62.824 1.00 88.78 N +ATOM 10169 CA ARG F 83 55.883 -18.391 61.524 1.00108.08 C +ATOM 10170 C ARG F 83 54.879 -19.421 60.901 1.00124.62 C +ATOM 10171 O ARG F 83 54.121 -19.066 59.996 1.00 81.13 O +ATOM 10172 CB ARG F 83 57.051 -18.112 60.579 1.00 86.38 C +ATOM 10173 CG ARG F 83 58.027 -17.111 61.119 1.00 78.98 C +ATOM 10174 CD ARG F 83 57.440 -15.717 61.167 1.00106.24 C +ATOM 10175 NE ARG F 83 58.529 -14.794 61.468 1.00125.47 N +ATOM 10176 CZ ARG F 83 58.765 -14.223 62.651 1.00115.61 C +ATOM 10177 NH1 ARG F 83 57.912 -14.377 63.669 1.00 96.09 N +ATOM 10178 NH2 ARG F 83 59.856 -13.455 62.789 1.00 99.19 N +ATOM 10179 N GLN F 84 54.874 -20.677 61.364 1.00134.74 N +ATOM 10180 CA GLN F 84 53.968 -21.673 60.772 1.00118.67 C +ATOM 10181 C GLN F 84 52.542 -21.253 60.988 1.00 87.34 C +ATOM 10182 O GLN F 84 51.737 -21.269 60.068 1.00145.27 O +ATOM 10183 CB GLN F 84 54.177 -23.075 61.321 1.00129.80 C +ATOM 10184 CG GLN F 84 53.825 -24.183 60.325 1.00136.37 C +ATOM 10185 CD GLN F 84 53.892 -25.550 60.977 1.00186.29 C +ATOM 10186 OE1 GLN F 84 54.832 -25.846 61.748 1.00310.63 O +ATOM 10187 NE2 GLN F 84 52.975 -26.434 60.602 1.00165.65 N +ATOM 10188 N GLY F 85 52.250 -20.694 62.139 1.00 77.34 N +ATOM 10189 CA GLY F 85 50.905 -20.147 62.340 1.00107.39 C +ATOM 10190 C GLY F 85 50.880 -18.630 62.433 1.00106.68 C +ATOM 10191 O GLY F 85 50.068 -18.076 63.195 1.00141.07 O +ATOM 10192 N LEU F 86 51.664 -17.952 61.586 1.00 80.65 N +ATOM 10193 CA LEU F 86 51.817 -16.501 61.691 1.00 70.51 C +ATOM 10194 C LEU F 86 50.472 -15.733 61.613 1.00 84.88 C +ATOM 10195 O LEU F 86 50.275 -14.713 62.290 1.00 74.30 O +ATOM 10196 CB LEU F 86 52.739 -15.969 60.600 1.00 77.82 C +ATOM 10197 CG LEU F 86 52.954 -14.445 60.433 1.00 99.33 C +ATOM 10198 CD1 LEU F 86 53.519 -13.796 61.688 1.00 99.82 C +ATOM 10199 CD2 LEU F 86 53.876 -14.165 59.251 1.00109.46 C +ATOM 10200 N GLN F 87 49.541 -16.219 60.795 1.00 85.80 N +ATOM 10201 CA GLN F 87 48.288 -15.498 60.568 1.00 91.19 C +ATOM 10202 C GLN F 87 47.461 -15.322 61.872 1.00 62.94 C +ATOM 10203 O GLN F 87 46.936 -14.257 62.181 1.00 71.15 O +ATOM 10204 CB GLN F 87 47.484 -16.211 59.463 1.00123.89 C +ATOM 10205 CG GLN F 87 46.677 -15.265 58.578 1.00147.01 C +ATOM 10206 CD GLN F 87 47.442 -14.004 58.175 1.00150.34 C +ATOM 10207 OE1 GLN F 87 48.517 -14.072 57.578 1.00125.59 O +ATOM 10208 NE2 GLN F 87 46.878 -12.838 58.503 1.00172.88 N +ATOM 10209 N ASN F 88 47.343 -16.393 62.614 1.00 60.69 N +ATOM 10210 CA ASN F 88 46.664 -16.367 63.882 1.00 76.43 C +ATOM 10211 C ASN F 88 47.344 -15.405 64.850 1.00 84.17 C +ATOM 10212 O ASN F 88 46.698 -14.824 65.737 1.00 87.04 O +ATOM 10213 CB ASN F 88 46.680 -17.779 64.508 1.00114.80 C +ATOM 10214 CG ASN F 88 46.036 -18.803 63.620 1.00 94.81 C +ATOM 10215 OD1 ASN F 88 45.071 -18.474 62.932 1.00 46.42 O +ATOM 10216 ND2 ASN F 88 46.632 -20.016 63.548 1.00 88.42 N +ATOM 10217 N LEU F 89 48.673 -15.389 64.806 1.00 89.33 N +ATOM 10218 CA LEU F 89 49.460 -14.603 65.733 1.00 90.84 C +ATOM 10219 C LEU F 89 49.070 -13.124 65.490 1.00109.90 C +ATOM 10220 O LEU F 89 48.850 -12.350 66.435 1.00105.34 O +ATOM 10221 CB LEU F 89 50.963 -14.886 65.493 1.00 64.18 C +ATOM 10222 CG LEU F 89 51.967 -14.732 66.621 1.00 53.05 C +ATOM 10223 CD1 LEU F 89 52.908 -13.591 66.341 1.00 58.53 C +ATOM 10224 CD2 LEU F 89 51.274 -14.463 67.955 1.00 56.31 C +ATOM 10225 N LEU F 90 48.957 -12.769 64.217 1.00108.44 N +ATOM 10226 CA LEU F 90 48.669 -11.392 63.835 1.00104.87 C +ATOM 10227 C LEU F 90 47.239 -11.041 64.206 1.00109.75 C +ATOM 10228 O LEU F 90 46.912 -9.887 64.516 1.00150.75 O +ATOM 10229 CB LEU F 90 48.885 -11.205 62.340 1.00 85.38 C +ATOM 10230 CG LEU F 90 50.307 -11.467 61.902 1.00 93.48 C +ATOM 10231 CD1 LEU F 90 50.333 -11.712 60.400 1.00101.45 C +ATOM 10232 CD2 LEU F 90 51.192 -10.294 62.299 1.00118.26 C +ATOM 10233 N ASN F 91 46.386 -12.052 64.189 1.00 98.15 N +ATOM 10234 CA ASN F 91 45.010 -11.860 64.559 1.00 97.41 C +ATOM 10235 C ASN F 91 44.860 -11.575 66.036 1.00115.28 C +ATOM 10236 O ASN F 91 44.124 -10.660 66.422 1.00132.20 O +ATOM 10237 CB ASN F 91 44.168 -13.059 64.158 1.00102.14 C +ATOM 10238 CG ASN F 91 42.959 -12.611 63.381 1.00 82.21 C +ATOM 10239 OD1 ASN F 91 43.128 -11.949 62.357 1.00 68.09 O +ATOM 10240 ND2 ASN F 91 41.747 -12.839 63.910 1.00 85.99 N +ATOM 10241 N GLU F 92 45.499 -12.398 66.860 1.00104.09 N +ATOM 10242 CA GLU F 92 45.417 -12.192 68.293 1.00115.01 C +ATOM 10243 C GLU F 92 45.927 -10.797 68.619 1.00102.17 C +ATOM 10244 O GLU F 92 45.447 -10.137 69.564 1.00107.40 O +ATOM 10245 CB GLU F 92 46.214 -13.257 69.055 1.00117.36 C +ATOM 10246 CG GLU F 92 45.392 -14.457 69.492 1.00 91.75 C +ATOM 10247 CD GLU F 92 44.125 -14.072 70.267 1.00 85.37 C +ATOM 10248 OE1 GLU F 92 44.208 -13.415 71.363 1.00 64.34 O +ATOM 10249 OE2 GLU F 92 43.043 -14.521 69.822 1.00 75.64 O +ATOM 10250 N ARG F 93 46.963 -10.379 67.902 1.00 74.77 N +ATOM 10251 CA ARG F 93 47.516 -9.054 68.128 1.00 98.09 C +ATOM 10252 C ARG F 93 46.519 -7.947 67.694 1.00125.42 C +ATOM 10253 O ARG F 93 46.436 -6.892 68.323 1.00142.66 O +ATOM 10254 CB ARG F 93 48.871 -8.946 67.444 1.00 86.95 C +ATOM 10255 CG ARG F 93 49.908 -9.815 68.119 1.00 72.72 C +ATOM 10256 CD ARG F 93 51.160 -10.029 67.280 1.00 86.81 C +ATOM 10257 NE ARG F 93 52.268 -9.187 67.712 1.00 91.19 N +ATOM 10258 CZ ARG F 93 52.620 -8.038 67.145 1.00101.85 C +ATOM 10259 NH1 ARG F 93 51.945 -7.539 66.117 1.00121.26 N +ATOM 10260 NH2 ARG F 93 53.677 -7.393 67.607 1.00117.37 N +ATOM 10261 N LYS F 94 45.711 -8.210 66.668 1.00115.73 N +ATOM 10262 CA LYS F 94 44.650 -7.273 66.292 1.00 90.39 C +ATOM 10263 C LYS F 94 43.651 -7.180 67.425 1.00 82.27 C +ATOM 10264 O LYS F 94 43.145 -6.068 67.728 1.00 77.86 O +ATOM 10265 CB LYS F 94 43.919 -7.736 65.044 1.00113.03 C +ATOM 10266 CG LYS F 94 44.507 -7.268 63.721 1.00131.56 C +ATOM 10267 CD LYS F 94 43.795 -7.969 62.565 1.00135.73 C +ATOM 10268 CE LYS F 94 43.948 -7.243 61.241 1.00120.07 C +ATOM 10269 NZ LYS F 94 43.540 -8.138 60.123 1.00132.70 N +ATOM 10270 N ILE F 95 43.365 -8.331 68.059 1.00 60.78 N +ATOM 10271 CA ILE F 95 42.308 -8.370 69.073 1.00 69.58 C +ATOM 10272 C ILE F 95 42.748 -7.652 70.345 1.00 73.32 C +ATOM 10273 O ILE F 95 41.949 -6.910 70.996 1.00 34.25 O +ATOM 10274 CB ILE F 95 41.867 -9.779 69.447 1.00 51.74 C +ATOM 10275 CG1 ILE F 95 41.550 -10.575 68.221 1.00 60.89 C +ATOM 10276 CG2 ILE F 95 40.583 -9.647 70.267 1.00 69.37 C +ATOM 10277 CD1 ILE F 95 40.778 -11.844 68.471 1.00 88.13 C +ATOM 10278 N ILE F 96 44.032 -7.860 70.657 1.00 82.84 N +ATOM 10279 CA ILE F 96 44.705 -7.130 71.738 1.00 79.34 C +ATOM 10280 C ILE F 96 44.598 -5.645 71.503 1.00 82.32 C +ATOM 10281 O ILE F 96 44.038 -4.926 72.320 1.00 86.70 O +ATOM 10282 CB ILE F 96 46.191 -7.506 71.871 1.00 62.35 C +ATOM 10283 CG1 ILE F 96 46.296 -8.951 72.330 1.00 83.38 C +ATOM 10284 CG2 ILE F 96 46.850 -6.633 72.898 1.00 47.20 C +ATOM 10285 CD1 ILE F 96 47.721 -9.395 72.552 1.00113.08 C +ATOM 10286 N ARG F 97 45.113 -5.190 70.362 1.00 80.08 N +ATOM 10287 CA ARG F 97 45.149 -3.752 70.062 1.00 79.79 C +ATOM 10288 C ARG F 97 43.742 -3.131 70.046 1.00 70.09 C +ATOM 10289 O ARG F 97 43.566 -1.960 70.399 1.00 48.28 O +ATOM 10290 CB ARG F 97 45.855 -3.478 68.730 1.00 86.40 C +ATOM 10291 CG ARG F 97 47.283 -2.970 68.860 1.00 96.85 C +ATOM 10292 CD ARG F 97 47.873 -2.655 67.496 1.00 99.06 C +ATOM 10293 NE ARG F 97 48.357 -3.858 66.820 1.00 93.62 N +ATOM 10294 CZ ARG F 97 49.635 -4.252 66.804 1.00 97.41 C +ATOM 10295 NH1 ARG F 97 50.603 -3.544 67.408 1.00 64.89 N +ATOM 10296 NH2 ARG F 97 49.955 -5.371 66.168 1.00117.15 N +ATOM 10297 N ALA F 98 42.753 -3.927 69.654 1.00 57.21 N +ATOM 10298 CA ALA F 98 41.393 -3.456 69.643 1.00 68.05 C +ATOM 10299 C ALA F 98 40.839 -3.359 71.072 1.00 82.12 C +ATOM 10300 O ALA F 98 39.945 -2.539 71.366 1.00 57.06 O +ATOM 10301 CB ALA F 98 40.541 -4.369 68.777 1.00 58.93 C +ATOM 10302 N ALA F 99 41.355 -4.229 71.940 1.00 98.26 N +ATOM 10303 CA ALA F 99 40.919 -4.277 73.329 1.00 93.80 C +ATOM 10304 C ALA F 99 41.325 -2.997 74.072 1.00 76.35 C +ATOM 10305 O ALA F 99 40.541 -2.404 74.796 1.00 40.80 O +ATOM 10306 CB ALA F 99 41.478 -5.537 74.017 1.00 78.33 C +ATOM 10307 N GLN F 100 42.605 -2.665 73.972 1.00103.41 N +ATOM 10308 CA GLN F 100 43.240 -1.759 74.938 1.00125.28 C +ATOM 10309 C GLN F 100 43.520 -0.394 74.359 1.00116.44 C +ATOM 10310 O GLN F 100 44.154 0.437 75.013 1.00127.03 O +ATOM 10311 CB GLN F 100 44.534 -2.374 75.531 1.00127.26 C +ATOM 10312 CG GLN F 100 45.436 -3.092 74.539 1.00113.10 C +ATOM 10313 CD GLN F 100 46.281 -4.206 75.154 1.00126.12 C +ATOM 10314 OE1 GLN F 100 45.771 -5.173 75.755 1.00123.34 O +ATOM 10315 NE2 GLN F 100 47.592 -4.065 75.015 1.00142.86 N +ATOM 10316 N GLU F 101 43.048 -0.158 73.139 1.00106.30 N +ATOM 10317 CA GLU F 101 43.291 1.128 72.468 1.00121.00 C +ATOM 10318 C GLU F 101 42.573 2.309 73.151 1.00117.03 C +ATOM 10319 O GLU F 101 43.006 3.453 73.027 1.00102.83 O +ATOM 10320 CB GLU F 101 42.905 1.054 70.990 1.00106.12 C +ATOM 10321 CG GLU F 101 41.497 0.544 70.733 1.00138.05 C +ATOM 10322 CD GLU F 101 41.124 0.565 69.253 1.00120.86 C +ATOM 10323 OE1 GLU F 101 42.052 0.661 68.424 1.00 91.02 O +ATOM 10324 OE2 GLU F 101 39.901 0.501 68.938 1.00 84.47 O +ATOM 10325 N ASN F 102 41.505 2.024 73.893 1.00 94.44 N +ATOM 10326 CA ASN F 102 40.741 3.076 74.529 1.00 83.60 C +ATOM 10327 C ASN F 102 41.207 3.365 75.959 1.00112.48 C +ATOM 10328 O ASN F 102 40.670 4.261 76.619 1.00122.69 O +ATOM 10329 CB ASN F 102 39.257 2.709 74.552 1.00 75.80 C +ATOM 10330 CG ASN F 102 38.613 2.801 73.208 1.00 71.56 C +ATOM 10331 OD1 ASN F 102 38.390 3.905 72.672 1.00 81.76 O +ATOM 10332 ND2 ASN F 102 38.422 1.641 72.586 1.00 75.57 N +ATOM 10333 N GLY F 103 42.169 2.594 76.466 1.00125.28 N +ATOM 10334 CA GLY F 103 42.665 2.797 77.836 1.00113.74 C +ATOM 10335 C GLY F 103 41.614 2.620 78.918 1.00 93.99 C +ATOM 10336 O GLY F 103 41.622 3.318 79.937 1.00115.91 O +ATOM 10337 N THR F 104 40.680 1.720 78.679 1.00 71.89 N +ATOM 10338 CA THR F 104 39.775 1.321 79.713 1.00 76.94 C +ATOM 10339 C THR F 104 40.232 -0.002 80.271 1.00 94.29 C +ATOM 10340 O THR F 104 39.973 -0.284 81.442 1.00147.36 O +ATOM 10341 CB THR F 104 38.322 1.198 79.221 1.00 91.71 C +ATOM 10342 OG1 THR F 104 38.193 0.159 78.229 1.00108.46 O +ATOM 10343 CG2 THR F 104 37.857 2.523 78.637 1.00105.42 C +ATOM 10344 N VAL F 105 40.932 -0.811 79.474 1.00105.01 N +ATOM 10345 CA VAL F 105 41.267 -2.176 79.911 1.00134.75 C +ATOM 10346 C VAL F 105 42.089 -2.172 81.205 1.00139.01 C +ATOM 10347 O VAL F 105 42.955 -1.313 81.411 1.00147.77 O +ATOM 10348 CB VAL F 105 41.974 -3.019 78.814 1.00159.17 C +ATOM 10349 CG1 VAL F 105 42.979 -4.011 79.411 1.00152.91 C +ATOM 10350 CG2 VAL F 105 40.948 -3.779 77.964 1.00174.22 C +ATOM 10351 N ALA F 106 41.751 -3.114 82.089 1.00139.60 N +ATOM 10352 CA ALA F 106 42.273 -3.167 83.447 1.00128.67 C +ATOM 10353 C ALA F 106 43.784 -3.345 83.430 1.00129.59 C +ATOM 10354 O ALA F 106 44.310 -4.197 82.707 1.00168.53 O +ATOM 10355 CB ALA F 106 41.604 -4.302 84.220 1.00123.25 C +ATOM 10356 N ILE F 107 44.472 -2.550 84.245 1.00127.96 N +ATOM 10357 CA ILE F 107 45.938 -2.518 84.261 1.00136.07 C +ATOM 10358 C ILE F 107 46.590 -3.896 84.555 1.00132.56 C +ATOM 10359 O ILE F 107 47.674 -4.207 84.062 1.00 97.66 O +ATOM 10360 CB ILE F 107 46.441 -1.457 85.269 1.00133.25 C +ATOM 10361 CG1 ILE F 107 47.933 -1.177 85.071 1.00133.36 C +ATOM 10362 CG2 ILE F 107 46.167 -1.897 86.706 1.00145.66 C +ATOM 10363 CD1 ILE F 107 48.310 -0.714 83.677 1.00112.28 C +ATOM 10364 N ASN F 108 45.906 -4.723 85.338 1.00152.30 N +ATOM 10365 CA ASN F 108 46.342 -6.098 85.606 1.00147.71 C +ATOM 10366 C ASN F 108 46.194 -6.972 84.366 1.00142.44 C +ATOM 10367 O ASN F 108 46.986 -7.882 84.127 1.00150.16 O +ATOM 10368 CB ASN F 108 45.508 -6.721 86.738 1.00173.91 C +ATOM 10369 CG ASN F 108 45.026 -5.700 87.753 1.00198.57 C +ATOM 10370 OD1 ASN F 108 45.743 -5.356 88.692 1.00233.78 O +ATOM 10371 ND2 ASN F 108 43.813 -5.191 87.555 1.00209.91 N +ATOM 10372 N ASN F 109 45.137 -6.715 83.606 1.00139.69 N +ATOM 10373 CA ASN F 109 44.782 -7.529 82.450 1.00144.30 C +ATOM 10374 C ASN F 109 45.512 -7.112 81.166 1.00138.11 C +ATOM 10375 O ASN F 109 45.563 -7.875 80.194 1.00124.71 O +ATOM 10376 CB ASN F 109 43.269 -7.461 82.223 1.00163.30 C +ATOM 10377 CG ASN F 109 42.592 -8.804 82.408 1.00169.68 C +ATOM 10378 OD1 ASN F 109 42.071 -9.381 81.455 1.00144.48 O +ATOM 10379 ND2 ASN F 109 42.639 -9.330 83.625 1.00172.68 N +ATOM 10380 N ARG F 110 46.077 -5.905 81.184 1.00127.62 N +ATOM 10381 CA ARG F 110 46.703 -5.285 80.005 1.00104.97 C +ATOM 10382 C ARG F 110 47.801 -6.175 79.415 1.00107.90 C +ATOM 10383 O ARG F 110 48.635 -6.709 80.152 1.00120.02 O +ATOM 10384 CB ARG F 110 47.308 -3.926 80.407 1.00 90.29 C +ATOM 10385 CG ARG F 110 47.478 -2.939 79.273 1.00 82.71 C +ATOM 10386 CD ARG F 110 47.263 -1.510 79.728 1.00 86.73 C +ATOM 10387 NE ARG F 110 48.512 -0.903 80.203 1.00104.68 N +ATOM 10388 CZ ARG F 110 49.100 0.173 79.658 1.00112.99 C +ATOM 10389 NH1 ARG F 110 48.554 0.822 78.613 1.00 83.07 N +ATOM 10390 NH2 ARG F 110 50.254 0.616 80.168 1.00108.45 N +ATOM 10391 N ILE F 111 47.808 -6.341 78.092 1.00 91.10 N +ATOM 10392 CA ILE F 111 48.901 -7.055 77.428 1.00 80.78 C +ATOM 10393 C ILE F 111 49.782 -6.104 76.665 1.00 77.83 C +ATOM 10394 O ILE F 111 49.319 -5.484 75.720 1.00 90.31 O +ATOM 10395 CB ILE F 111 48.383 -8.105 76.456 1.00 86.07 C +ATOM 10396 CG1 ILE F 111 47.601 -9.173 77.233 1.00127.21 C +ATOM 10397 CG2 ILE F 111 49.544 -8.748 75.710 1.00 77.58 C +ATOM 10398 CD1 ILE F 111 46.792 -10.122 76.365 1.00156.97 C +ATOM 10399 N PRO F 112 51.061 -5.976 77.068 1.00 87.13 N +ATOM 10400 CA PRO F 112 51.965 -5.055 76.392 1.00 88.71 C +ATOM 10401 C PRO F 112 52.491 -5.655 75.079 1.00104.22 C +ATOM 10402 O PRO F 112 52.960 -6.803 75.051 1.00 70.90 O +ATOM 10403 CB PRO F 112 53.100 -4.886 77.394 1.00 87.12 C +ATOM 10404 CG PRO F 112 53.174 -6.208 78.083 1.00103.44 C +ATOM 10405 CD PRO F 112 51.781 -6.806 78.049 1.00108.09 C +ATOM 10406 N LEU F 113 52.372 -4.881 74.003 1.00109.50 N +ATOM 10407 CA LEU F 113 52.677 -5.371 72.673 1.00 86.91 C +ATOM 10408 C LEU F 113 53.975 -4.801 72.160 1.00 94.46 C +ATOM 10409 O LEU F 113 54.291 -3.621 72.329 1.00128.62 O +ATOM 10410 CB LEU F 113 51.531 -5.065 71.707 1.00 88.30 C +ATOM 10411 CG LEU F 113 50.407 -6.111 71.657 1.00 80.45 C +ATOM 10412 CD1 LEU F 113 49.431 -5.712 70.592 1.00 67.84 C +ATOM 10413 CD2 LEU F 113 50.958 -7.505 71.372 1.00 96.90 C +ATOM 10414 N GLN F 114 54.717 -5.665 71.502 1.00 96.26 N +ATOM 10415 CA GLN F 114 56.093 -5.399 71.146 1.00113.84 C +ATOM 10416 C GLN F 114 56.181 -5.874 69.726 1.00119.93 C +ATOM 10417 O GLN F 114 55.484 -6.829 69.350 1.00174.08 O +ATOM 10418 CB GLN F 114 57.025 -6.202 72.048 1.00107.43 C +ATOM 10419 CG GLN F 114 58.403 -5.604 72.266 1.00135.28 C +ATOM 10420 CD GLN F 114 59.435 -6.685 72.637 1.00138.58 C +ATOM 10421 OE1 GLN F 114 59.065 -7.712 73.194 1.00 95.10 O +ATOM 10422 NE2 GLN F 114 60.711 -6.466 72.290 1.00113.54 N +ATOM 10423 N SER F 115 57.002 -5.212 68.928 1.00 94.14 N +ATOM 10424 CA SER F 115 57.089 -5.561 67.507 1.00105.02 C +ATOM 10425 C SER F 115 57.515 -7.010 67.326 1.00 76.43 C +ATOM 10426 O SER F 115 58.105 -7.598 68.269 1.00104.78 O +ATOM 10427 CB SER F 115 58.107 -4.658 66.835 1.00122.62 C +ATOM 10428 OG SER F 115 59.329 -4.631 67.567 1.00 67.08 O +ATOM 10429 N LEU F 116 57.200 -7.622 66.182 1.00 46.37 N +ATOM 10430 CA LEU F 116 57.372 -9.063 66.144 1.00 57.54 C +ATOM 10431 C LEU F 116 58.838 -9.338 66.017 1.00 59.03 C +ATOM 10432 O LEU F 116 59.486 -8.742 65.174 1.00 58.82 O +ATOM 10433 CB LEU F 116 56.641 -9.712 64.990 1.00 71.82 C +ATOM 10434 CG LEU F 116 55.112 -9.661 65.041 1.00 88.58 C +ATOM 10435 CD1 LEU F 116 54.572 -8.473 64.262 1.00 78.56 C +ATOM 10436 CD2 LEU F 116 54.588 -10.983 64.487 1.00106.50 C +ATOM 10437 N THR F 117 59.386 -10.130 66.941 1.00 75.34 N +ATOM 10438 CA THR F 117 60.812 -10.402 66.976 1.00 98.70 C +ATOM 10439 C THR F 117 61.153 -11.013 65.631 1.00115.09 C +ATOM 10440 O THR F 117 60.454 -11.911 65.173 1.00 81.66 O +ATOM 10441 CB THR F 117 61.183 -11.403 68.094 1.00125.74 C +ATOM 10442 OG1 THR F 117 60.759 -10.889 69.360 1.00 90.84 O +ATOM 10443 CG2 THR F 117 62.692 -11.607 68.151 1.00162.23 C +ATOM 10444 N ALA F 118 62.255 -10.553 65.034 1.00129.45 N +ATOM 10445 CA ALA F 118 62.580 -10.886 63.646 1.00106.64 C +ATOM 10446 C ALA F 118 63.847 -11.669 63.552 1.00 80.59 C +ATOM 10447 O ALA F 118 64.844 -11.358 64.233 1.00 65.05 O +ATOM 10448 CB ALA F 118 62.703 -9.625 62.815 1.00138.49 C +ATOM 10449 N ALA F 119 63.816 -12.643 62.659 1.00 74.98 N +ATOM 10450 CA ALA F 119 64.916 -13.590 62.510 1.00 92.16 C +ATOM 10451 C ALA F 119 66.026 -13.071 61.590 1.00 88.17 C +ATOM 10452 O ALA F 119 65.773 -12.241 60.726 1.00 66.18 O +ATOM 10453 CB ALA F 119 64.378 -14.892 61.975 1.00 84.82 C +ATOM 10454 N ASN F 120 67.247 -13.581 61.765 1.00 95.14 N +ATOM 10455 CA ASN F 120 68.326 -13.241 60.848 1.00115.93 C +ATOM 10456 C ASN F 120 68.545 -14.306 59.791 1.00137.65 C +ATOM 10457 O ASN F 120 68.765 -14.011 58.614 1.00161.28 O +ATOM 10458 CB ASN F 120 69.649 -13.000 61.568 1.00126.51 C +ATOM 10459 CG ASN F 120 70.754 -12.568 60.599 1.00144.62 C +ATOM 10460 OD1 ASN F 120 71.897 -12.990 60.741 1.00180.59 O +ATOM 10461 ND2 ASN F 120 70.405 -11.753 59.580 1.00128.38 N +ATOM 10462 N ILE F 121 68.599 -15.556 60.225 1.00116.36 N +ATOM 10463 CA ILE F 121 68.688 -16.647 59.278 1.00 80.72 C +ATOM 10464 C ILE F 121 67.386 -17.373 59.337 1.00 67.66 C +ATOM 10465 O ILE F 121 66.790 -17.514 60.391 1.00 58.17 O +ATOM 10466 CB ILE F 121 69.875 -17.601 59.564 1.00 74.17 C +ATOM 10467 CG1 ILE F 121 69.623 -18.496 60.797 1.00 64.40 C +ATOM 10468 CG2 ILE F 121 71.195 -16.813 59.696 1.00 64.59 C +ATOM 10469 CD1 ILE F 121 69.415 -19.962 60.475 1.00 55.08 C +ATOM 10470 N MET F 122 66.910 -17.802 58.186 1.00 83.79 N +ATOM 10471 CA MET F 122 65.802 -18.744 58.183 1.00110.74 C +ATOM 10472 C MET F 122 66.183 -20.029 57.459 1.00105.93 C +ATOM 10473 O MET F 122 67.025 -20.001 56.566 1.00107.66 O +ATOM 10474 CB MET F 122 64.567 -18.096 57.573 1.00118.60 C +ATOM 10475 CG MET F 122 64.737 -17.584 56.157 1.00121.48 C +ATOM 10476 SD MET F 122 63.156 -17.647 55.304 1.00 89.88 S +ATOM 10477 CE MET F 122 63.627 -18.236 53.682 1.00 66.71 C +ATOM 10478 N VAL F 123 65.727 -21.151 57.986 1.00 97.59 N +ATOM 10479 CA VAL F 123 66.117 -22.448 57.451 1.00 98.89 C +ATOM 10480 C VAL F 123 64.867 -23.120 56.882 1.00104.33 C +ATOM 10481 O VAL F 123 63.890 -23.285 57.587 1.00 92.62 O +ATOM 10482 CB VAL F 123 66.839 -23.357 58.494 1.00 86.37 C +ATOM 10483 CG1 VAL F 123 66.167 -23.241 59.862 1.00106.21 C +ATOM 10484 CG2 VAL F 123 66.860 -24.823 58.016 1.00114.32 C +ATOM 10485 N GLU F 124 64.972 -23.599 55.664 1.00121.71 N +ATOM 10486 CA GLU F 124 63.908 -24.378 55.110 1.00123.85 C +ATOM 10487 C GLU F 124 64.483 -25.603 54.460 1.00139.45 C +ATOM 10488 O GLU F 124 65.690 -25.722 54.289 1.00153.74 O +ATOM 10489 CB GLU F 124 63.102 -23.573 54.106 1.00153.72 C +ATOM 10490 CG GLU F 124 63.852 -22.483 53.347 1.00173.99 C +ATOM 10491 CD GLU F 124 62.904 -21.482 52.675 1.00176.55 C +ATOM 10492 OE1 GLU F 124 61.833 -21.183 53.227 1.00113.32 O +ATOM 10493 OE2 GLU F 124 63.220 -21.012 51.564 1.00197.97 O +ATOM 10494 N GLY F 125 63.608 -26.515 54.078 1.00147.00 N +ATOM 10495 CA GLY F 125 64.045 -27.773 53.507 1.00139.41 C +ATOM 10496 C GLY F 125 62.895 -28.568 52.958 1.00124.36 C +ATOM 10497 O GLY F 125 61.807 -28.036 52.712 1.00141.96 O +ATOM 10498 N SER F 126 63.125 -29.859 52.772 1.00102.75 N +ATOM 10499 CA SER F 126 62.115 -30.703 52.153 1.00122.77 C +ATOM 10500 C SER F 126 62.376 -32.150 52.487 1.00 94.79 C +ATOM 10501 O SER F 126 63.512 -32.546 52.685 1.00150.60 O +ATOM 10502 CB SER F 126 62.146 -30.550 50.632 1.00142.43 C +ATOM 10503 OG SER F 126 62.560 -29.250 50.226 1.00136.29 O +ATOM 10504 N ILE F 127 61.321 -32.941 52.599 1.00 76.06 N +ATOM 10505 CA ILE F 127 61.497 -34.372 52.623 1.00 60.11 C +ATOM 10506 C ILE F 127 61.714 -34.738 51.174 1.00 67.75 C +ATOM 10507 O ILE F 127 60.780 -34.880 50.405 1.00 81.10 O +ATOM 10508 CB ILE F 127 60.320 -35.138 53.254 1.00 55.50 C +ATOM 10509 CG1 ILE F 127 60.204 -34.821 54.755 1.00 54.94 C +ATOM 10510 CG2 ILE F 127 60.469 -36.645 53.063 1.00 50.05 C +ATOM 10511 CD1 ILE F 127 58.763 -34.861 55.276 1.00 73.94 C +ATOM 10512 N ILE F 128 62.966 -34.994 50.850 1.00 92.75 N +ATOM 10513 CA ILE F 128 63.369 -35.465 49.543 1.00129.01 C +ATOM 10514 C ILE F 128 63.359 -37.004 49.587 1.00142.62 C +ATOM 10515 O ILE F 128 64.230 -37.656 50.174 1.00268.39 O +ATOM 10516 CB ILE F 128 64.751 -34.881 49.180 1.00160.00 C +ATOM 10517 CG1 ILE F 128 65.791 -35.207 50.262 1.00158.23 C +ATOM 10518 CG2 ILE F 128 64.666 -33.360 49.122 1.00158.36 C +ATOM 10519 CD1 ILE F 128 67.211 -35.189 49.736 1.00190.07 C +ATOM 10520 N GLY F 129 62.276 -37.587 49.091 1.00108.24 N +ATOM 10521 CA GLY F 129 62.252 -39.002 48.807 1.00107.57 C +ATOM 10522 C GLY F 129 61.847 -39.924 49.952 1.00123.13 C +ATOM 10523 O GLY F 129 62.352 -39.840 51.091 1.00180.19 O +ATOM 10524 N TYR F 130 61.024 -40.900 49.590 1.00126.52 N +ATOM 10525 CA TYR F 130 60.834 -42.121 50.376 1.00 97.81 C +ATOM 10526 C TYR F 130 60.730 -43.272 49.397 1.00110.09 C +ATOM 10527 O TYR F 130 59.790 -43.332 48.621 1.00155.27 O +ATOM 10528 CB TYR F 130 59.561 -42.011 51.194 1.00 62.73 C +ATOM 10529 CG TYR F 130 59.185 -43.242 51.958 1.00 67.34 C +ATOM 10530 CD1 TYR F 130 58.817 -44.401 51.308 1.00 70.57 C +ATOM 10531 CD2 TYR F 130 59.112 -43.214 53.359 1.00 98.75 C +ATOM 10532 CE1 TYR F 130 58.397 -45.518 52.032 1.00 92.00 C +ATOM 10533 CE2 TYR F 130 58.712 -44.324 54.089 1.00102.23 C +ATOM 10534 CZ TYR F 130 58.359 -45.471 53.421 1.00 85.40 C +ATOM 10535 OH TYR F 130 57.963 -46.553 54.166 1.00 69.49 O +ATOM 10536 N GLU F 131 61.780 -44.076 49.302 1.00120.08 N +ATOM 10537 CA GLU F 131 61.714 -45.290 48.511 1.00111.09 C +ATOM 10538 C GLU F 131 61.340 -46.444 49.439 1.00116.58 C +ATOM 10539 O GLU F 131 61.714 -46.443 50.620 1.00114.70 O +ATOM 10540 CB GLU F 131 63.047 -45.515 47.819 1.00110.20 C +ATOM 10541 CG GLU F 131 63.048 -46.628 46.789 1.00139.33 C +ATOM 10542 CD GLU F 131 62.606 -46.175 45.402 1.00146.55 C +ATOM 10543 OE1 GLU F 131 62.836 -44.992 45.055 1.00123.00 O +ATOM 10544 OE2 GLU F 131 62.100 -47.029 44.632 1.00135.24 O +ATOM 10545 N SER F 132 60.606 -47.422 48.915 1.00105.30 N +ATOM 10546 CA SER F 132 60.050 -48.475 49.766 1.00122.74 C +ATOM 10547 C SER F 132 60.551 -49.872 49.367 1.00132.79 C +ATOM 10548 O SER F 132 60.696 -50.170 48.182 1.00147.71 O +ATOM 10549 CB SER F 132 58.524 -48.432 49.726 1.00124.89 C +ATOM 10550 OG SER F 132 57.999 -49.584 49.085 1.00152.10 O +ATOM 10551 N ASN F 133 60.782 -50.729 50.365 1.00123.17 N +ATOM 10552 CA ASN F 133 61.482 -52.015 50.171 1.00 94.32 C +ATOM 10553 C ASN F 133 62.740 -51.860 49.345 1.00107.57 C +ATOM 10554 O ASN F 133 62.888 -52.474 48.278 1.00 97.48 O +ATOM 10555 CB ASN F 133 60.569 -53.032 49.526 1.00 89.38 C +ATOM 10556 CG ASN F 133 59.343 -53.299 50.360 1.00123.46 C +ATOM 10557 OD1 ASN F 133 59.358 -53.199 51.596 1.00113.49 O +ATOM 10558 ND2 ASN F 133 58.253 -53.624 49.687 1.00162.85 N +ATOM 10559 N VAL F 134 63.637 -51.003 49.831 1.00129.01 N +ATOM 10560 CA VAL F 134 64.895 -50.717 49.149 1.00139.21 C +ATOM 10561 C VAL F 134 65.739 -51.979 49.253 1.00141.62 C +ATOM 10562 O VAL F 134 66.454 -52.345 48.313 1.00 95.73 O +ATOM 10563 CB VAL F 134 65.619 -49.503 49.785 1.00108.94 C +ATOM 10564 CG1 VAL F 134 66.891 -49.181 49.020 1.00117.36 C +ATOM 10565 CG2 VAL F 134 64.704 -48.285 49.781 1.00126.15 C +ATOM 10566 N LYS F 135 65.580 -52.676 50.380 1.00145.07 N +ATOM 10567 CA LYS F 135 66.036 -54.063 50.495 1.00133.46 C +ATOM 10568 C LYS F 135 65.042 -54.931 51.248 1.00 94.68 C +ATOM 10569 O LYS F 135 64.153 -54.438 51.952 1.00 55.92 O +ATOM 10570 CB LYS F 135 67.358 -54.131 51.245 1.00210.68 C +ATOM 10571 CG LYS F 135 68.500 -53.403 50.558 1.00255.85 C +ATOM 10572 CD LYS F 135 69.743 -53.426 51.429 1.00254.79 C +ATOM 10573 CE LYS F 135 70.894 -52.692 50.774 1.00225.60 C +ATOM 10574 NZ LYS F 135 72.183 -53.130 51.361 1.00224.61 N +ATOM 10575 N SER F 136 65.153 -56.233 51.015 1.00101.82 N +ATOM 10576 CA SER F 136 64.228 -57.196 51.601 1.00114.64 C +ATOM 10577 C SER F 136 64.752 -58.604 51.489 1.00115.21 C +ATOM 10578 O SER F 136 65.582 -58.913 50.623 1.00 87.31 O +ATOM 10579 CB SER F 136 62.844 -57.127 50.940 1.00151.02 C +ATOM 10580 OG SER F 136 62.416 -58.392 50.452 1.00154.30 O +ATOM 10581 N GLY F 137 64.282 -59.453 52.393 1.00123.33 N +ATOM 10582 CA GLY F 137 64.715 -60.841 52.401 1.00137.98 C +ATOM 10583 C GLY F 137 63.879 -61.724 53.302 1.00122.63 C +ATOM 10584 O GLY F 137 63.004 -61.250 54.014 1.00 73.30 O +ATOM 10585 N GLY F 138 64.158 -63.020 53.253 1.00112.48 N +ATOM 10586 CA GLY F 138 63.447 -63.961 54.079 1.00106.26 C +ATOM 10587 C GLY F 138 64.159 -65.284 54.167 1.00128.98 C +ATOM 10588 O GLY F 138 64.812 -65.728 53.212 1.00107.10 O +ATOM 10589 N VAL F 139 64.043 -65.915 55.333 1.00149.40 N +ATOM 10590 CA VAL F 139 64.605 -67.247 55.549 1.00142.10 C +ATOM 10591 C VAL F 139 63.617 -68.104 56.335 1.00114.49 C +ATOM 10592 O VAL F 139 63.176 -67.723 57.413 1.00 77.07 O +ATOM 10593 CB VAL F 139 65.944 -67.196 56.316 1.00122.77 C +ATOM 10594 CG1 VAL F 139 66.413 -68.602 56.625 1.00124.56 C +ATOM 10595 CG2 VAL F 139 67.001 -66.437 55.524 1.00116.06 C +ATOM 10596 N GLY F 140 63.289 -69.260 55.772 1.00110.04 N +ATOM 10597 CA GLY F 140 62.331 -70.155 56.376 1.00114.44 C +ATOM 10598 C GLY F 140 62.596 -71.610 56.049 1.00149.20 C +ATOM 10599 O GLY F 140 63.045 -71.961 54.948 1.00127.81 O +ATOM 10600 N ALA F 141 62.302 -72.472 57.011 1.00182.49 N +ATOM 10601 CA ALA F 141 62.417 -73.908 56.790 1.00190.47 C +ATOM 10602 C ALA F 141 61.295 -74.662 57.491 1.00225.03 C +ATOM 10603 O ALA F 141 60.887 -74.321 58.603 1.00203.65 O +ATOM 10604 CB ALA F 141 63.778 -74.417 57.237 1.00157.92 C +ATOM 10605 N ARG F 142 60.772 -75.668 56.806 1.00245.68 N +ATOM 10606 CA ARG F 142 59.841 -76.583 57.424 1.00225.01 C +ATOM 10607 C ARG F 142 60.329 -78.003 57.193 1.00239.23 C +ATOM 10608 O ARG F 142 60.920 -78.308 56.154 1.00221.69 O +ATOM 10609 CB ARG F 142 58.430 -76.396 56.875 1.00190.04 C +ATOM 10610 CG ARG F 142 57.403 -77.276 57.573 1.00184.53 C +ATOM 10611 CD ARG F 142 56.103 -76.544 57.851 1.00206.08 C +ATOM 10612 NE ARG F 142 55.242 -76.523 56.670 1.00227.86 N +ATOM 10613 CZ ARG F 142 54.301 -75.614 56.427 1.00226.61 C +ATOM 10614 NH1 ARG F 142 54.088 -74.620 57.280 1.00218.67 N +ATOM 10615 NH2 ARG F 142 53.571 -75.697 55.318 1.00221.16 N +ATOM 10616 N TYR F 143 60.130 -78.847 58.198 1.00248.18 N +ATOM 10617 CA TYR F 143 60.694 -80.195 58.207 1.00216.37 C +ATOM 10618 C TYR F 143 59.628 -81.243 58.550 1.00174.57 C +ATOM 10619 O TYR F 143 59.470 -81.647 59.704 1.00104.88 O +ATOM 10620 CB TYR F 143 61.854 -80.259 59.203 1.00206.63 C +ATOM 10621 CG TYR F 143 62.598 -81.555 59.179 1.00204.48 C +ATOM 10622 CD1 TYR F 143 63.431 -81.874 58.118 1.00186.91 C +ATOM 10623 CD2 TYR F 143 62.473 -82.464 60.220 1.00223.71 C +ATOM 10624 CE1 TYR F 143 64.123 -83.069 58.088 1.00207.87 C +ATOM 10625 CE2 TYR F 143 63.171 -83.660 60.210 1.00222.64 C +ATOM 10626 CZ TYR F 143 63.987 -83.960 59.136 1.00235.00 C +ATOM 10627 OH TYR F 143 64.670 -85.154 59.110 1.00294.95 O +ATOM 10628 N GLY F 145 57.125 -81.564 59.559 1.00152.13 N +ATOM 10629 CA GLY F 145 55.977 -81.140 60.349 1.00161.83 C +ATOM 10630 C GLY F 145 56.172 -79.813 61.077 1.00218.79 C +ATOM 10631 O GLY F 145 55.193 -79.134 61.383 1.00212.08 O +ATOM 10632 N ILE F 146 57.423 -79.431 61.348 1.00264.64 N +ATOM 10633 CA ILE F 146 57.741 -78.256 62.190 1.00239.26 C +ATOM 10634 C ILE F 146 58.426 -77.189 61.332 1.00232.16 C +ATOM 10635 O ILE F 146 59.280 -77.518 60.516 1.00179.28 O +ATOM 10636 CB ILE F 146 58.664 -78.630 63.387 1.00193.47 C +ATOM 10637 CG1 ILE F 146 58.259 -79.993 63.975 1.00189.73 C +ATOM 10638 CG2 ILE F 146 58.619 -77.554 64.467 1.00138.33 C +ATOM 10639 CD1 ILE F 146 59.070 -81.164 63.458 1.00161.96 C +ATOM 10640 N GLY F 147 58.056 -75.919 61.503 1.00226.50 N +ATOM 10641 CA GLY F 147 58.618 -74.862 60.656 1.00200.28 C +ATOM 10642 C GLY F 147 58.728 -73.482 61.281 1.00181.95 C +ATOM 10643 O GLY F 147 58.011 -73.142 62.218 1.00115.62 O +ATOM 10644 N ALA F 148 59.659 -72.692 60.762 1.00187.21 N +ATOM 10645 CA ALA F 148 59.765 -71.291 61.144 1.00167.94 C +ATOM 10646 C ALA F 148 60.260 -70.468 59.966 1.00158.25 C +ATOM 10647 O ALA F 148 60.722 -71.015 58.957 1.00123.38 O +ATOM 10648 CB ALA F 148 60.687 -71.124 62.344 1.00152.79 C +ATOM 10649 N ASP F 149 60.119 -69.154 60.086 1.00148.27 N +ATOM 10650 CA ASP F 149 60.597 -68.258 59.050 1.00153.36 C +ATOM 10651 C ASP F 149 60.650 -66.822 59.558 1.00135.45 C +ATOM 10652 O ASP F 149 59.851 -66.419 60.410 1.00 85.73 O +ATOM 10653 CB ASP F 149 59.714 -68.357 57.800 1.00181.80 C +ATOM 10654 CG ASP F 149 58.444 -67.564 57.925 1.00198.46 C +ATOM 10655 OD1 ASP F 149 57.533 -68.014 58.642 1.00181.00 O +ATOM 10656 OD2 ASP F 149 58.350 -66.502 57.287 1.00208.04 O +ATOM 10657 N THR F 150 61.608 -66.057 59.049 1.00139.85 N +ATOM 10658 CA THR F 150 61.566 -64.605 59.212 1.00137.88 C +ATOM 10659 C THR F 150 61.590 -63.941 57.846 1.00148.71 C +ATOM 10660 O THR F 150 62.055 -64.519 56.855 1.00 97.58 O +ATOM 10661 CB THR F 150 62.734 -64.051 60.055 1.00123.27 C +ATOM 10662 OG1 THR F 150 63.977 -64.397 59.431 1.00157.72 O +ATOM 10663 CG2 THR F 150 62.691 -64.594 61.456 1.00109.15 C +ATOM 10664 N GLN F 151 61.033 -62.739 57.798 1.00152.74 N +ATOM 10665 CA GLN F 151 61.081 -61.916 56.613 1.00152.26 C +ATOM 10666 C GLN F 151 61.387 -60.498 57.037 1.00133.83 C +ATOM 10667 O GLN F 151 60.935 -60.059 58.077 1.00 68.94 O +ATOM 10668 CB GLN F 151 59.735 -61.982 55.900 1.00167.20 C +ATOM 10669 CG GLN F 151 59.505 -63.309 55.202 1.00185.53 C +ATOM 10670 CD GLN F 151 58.047 -63.579 54.928 1.00182.68 C +ATOM 10671 OE1 GLN F 151 57.306 -62.665 54.579 1.00170.76 O +ATOM 10672 NE2 GLN F 151 57.615 -64.827 55.134 1.00185.70 N +ATOM 10673 N TYR F 152 62.192 -59.791 56.256 1.00140.04 N +ATOM 10674 CA TYR F 152 62.497 -58.409 56.583 1.00139.11 C +ATOM 10675 C TYR F 152 62.438 -57.515 55.362 1.00148.37 C +ATOM 10676 O TYR F 152 62.719 -57.953 54.237 1.00 88.06 O +ATOM 10677 CB TYR F 152 63.858 -58.315 57.264 1.00137.74 C +ATOM 10678 CG TYR F 152 65.021 -57.806 56.416 1.00140.09 C +ATOM 10679 CD1 TYR F 152 65.494 -58.507 55.312 1.00127.96 C +ATOM 10680 CD2 TYR F 152 65.687 -56.651 56.775 1.00138.60 C +ATOM 10681 CE1 TYR F 152 66.542 -58.011 54.540 1.00133.00 C +ATOM 10682 CE2 TYR F 152 66.783 -56.181 56.056 1.00129.70 C +ATOM 10683 CZ TYR F 152 67.197 -56.853 54.926 1.00131.60 C +ATOM 10684 OH TYR F 152 68.272 -56.360 54.197 1.00111.92 O +ATOM 10685 N GLN F 153 62.007 -56.274 55.581 1.00135.38 N +ATOM 10686 CA GLN F 153 62.074 -55.266 54.535 1.00147.51 C +ATOM 10687 C GLN F 153 62.597 -53.965 55.107 1.00107.23 C +ATOM 10688 O GLN F 153 62.478 -53.720 56.307 1.00 68.85 O +ATOM 10689 CB GLN F 153 60.691 -55.054 53.912 1.00179.68 C +ATOM 10690 CG GLN F 153 60.125 -56.259 53.147 1.00194.55 C +ATOM 10691 CD GLN F 153 58.693 -55.994 52.650 1.00188.84 C +ATOM 10692 OE1 GLN F 153 57.988 -55.122 53.177 1.00194.05 O +ATOM 10693 NE2 GLN F 153 58.250 -56.762 51.656 1.00175.76 N +ATOM 10694 N LEU F 154 63.217 -53.155 54.255 1.00103.25 N +ATOM 10695 CA LEU F 154 63.632 -51.836 54.684 1.00139.82 C +ATOM 10696 C LEU F 154 63.497 -50.775 53.598 1.00159.08 C +ATOM 10697 O LEU F 154 63.757 -51.023 52.405 1.00118.15 O +ATOM 10698 CB LEU F 154 65.064 -51.856 55.228 1.00164.98 C +ATOM 10699 CG LEU F 154 66.178 -52.033 54.189 1.00200.52 C +ATOM 10700 CD1 LEU F 154 66.745 -50.694 53.739 1.00193.46 C +ATOM 10701 CD2 LEU F 154 67.270 -52.925 54.762 1.00259.48 C +ATOM 10702 N ASP F 155 63.179 -49.566 54.071 1.00157.37 N +ATOM 10703 CA ASP F 155 62.793 -48.423 53.237 1.00131.68 C +ATOM 10704 C ASP F 155 63.790 -47.279 53.466 1.00102.03 C +ATOM 10705 O ASP F 155 64.455 -47.249 54.496 1.00 75.22 O +ATOM 10706 CB ASP F 155 61.359 -47.978 53.599 1.00125.94 C +ATOM 10707 CG ASP F 155 60.381 -49.148 53.702 1.00152.18 C +ATOM 10708 OD1 ASP F 155 60.393 -49.857 54.735 1.00159.65 O +ATOM 10709 OD2 ASP F 155 59.643 -49.390 52.727 1.00140.48 O +ATOM 10710 N GLN F 156 63.856 -46.324 52.539 1.00114.62 N +ATOM 10711 CA GLN F 156 64.707 -45.136 52.701 1.00126.69 C +ATOM 10712 C GLN F 156 63.910 -43.808 52.820 1.00134.91 C +ATOM 10713 O GLN F 156 62.749 -43.729 52.439 1.00178.92 O +ATOM 10714 CB GLN F 156 65.653 -45.033 51.522 1.00101.34 C +ATOM 10715 CG GLN F 156 66.766 -44.019 51.705 1.00123.69 C +ATOM 10716 CD GLN F 156 67.890 -44.195 50.693 1.00111.52 C +ATOM 10717 OE1 GLN F 156 67.833 -45.095 49.838 1.00 77.99 O +ATOM 10718 NE2 GLN F 156 68.989 -43.452 50.895 1.00 95.61 N +ATOM 10719 N ILE F 157 64.515 -42.811 53.450 1.00 95.11 N +ATOM 10720 CA ILE F 157 63.905 -41.524 53.615 1.00 59.19 C +ATOM 10721 C ILE F 157 65.037 -40.503 53.673 1.00 60.60 C +ATOM 10722 O ILE F 157 66.084 -40.734 54.304 1.00117.54 O +ATOM 10723 CB ILE F 157 63.016 -41.482 54.877 1.00 52.70 C +ATOM 10724 CG1 ILE F 157 61.985 -40.361 54.752 1.00105.14 C +ATOM 10725 CG2 ILE F 157 63.829 -41.216 56.117 1.00 59.02 C +ATOM 10726 CD1 ILE F 157 60.937 -40.334 55.857 1.00134.09 C +ATOM 10727 N ALA F 158 64.872 -39.377 53.014 1.00 70.67 N +ATOM 10728 CA ALA F 158 65.937 -38.374 52.970 1.00104.92 C +ATOM 10729 C ALA F 158 65.381 -36.987 53.168 1.00 89.89 C +ATOM 10730 O ALA F 158 64.221 -36.732 52.909 1.00 90.84 O +ATOM 10731 CB ALA F 158 66.718 -38.430 51.657 1.00116.63 C +ATOM 10732 N VAL F 159 66.226 -36.115 53.700 1.00 90.65 N +ATOM 10733 CA VAL F 159 65.791 -34.805 54.105 1.00 79.53 C +ATOM 10734 C VAL F 159 66.859 -33.815 53.672 1.00 62.37 C +ATOM 10735 O VAL F 159 68.004 -33.911 54.109 1.00106.59 O +ATOM 10736 CB VAL F 159 65.473 -34.747 55.653 1.00 89.64 C +ATOM 10737 CG1 VAL F 159 65.485 -33.313 56.191 1.00 86.23 C +ATOM 10738 CG2 VAL F 159 64.116 -35.398 55.961 1.00 81.43 C +ATOM 10739 N ASN F 160 66.426 -32.782 52.986 1.00 45.83 N +ATOM 10740 CA ASN F 160 67.196 -31.589 52.847 1.00 47.87 C +ATOM 10741 C ASN F 160 66.834 -30.538 53.928 1.00 49.98 C +ATOM 10742 O ASN F 160 65.652 -30.217 54.177 1.00 37.60 O +ATOM 10743 CB ASN F 160 66.968 -31.010 51.468 1.00 53.12 C +ATOM 10744 CG ASN F 160 67.958 -29.861 51.151 1.00 62.80 C +ATOM 10745 OD1 ASN F 160 68.950 -30.013 50.405 1.00 39.09 O +ATOM 10746 ND2 ASN F 160 67.707 -28.705 51.740 1.00 87.24 N +ATOM 10747 N LEU F 161 67.856 -29.991 54.591 1.00 56.43 N +ATOM 10748 CA LEU F 161 67.716 -28.715 55.312 1.00 57.85 C +ATOM 10749 C LEU F 161 68.709 -27.688 54.770 1.00 46.27 C +ATOM 10750 O LEU F 161 69.804 -28.025 54.391 1.00 30.91 O +ATOM 10751 CB LEU F 161 67.926 -28.916 56.809 1.00 57.87 C +ATOM 10752 CG LEU F 161 66.908 -29.810 57.497 1.00 73.73 C +ATOM 10753 CD1 LEU F 161 67.362 -30.100 58.914 1.00112.23 C +ATOM 10754 CD2 LEU F 161 65.545 -29.145 57.492 1.00 70.60 C +ATOM 10755 N ARG F 162 68.338 -26.420 54.815 1.00 49.42 N +ATOM 10756 CA ARG F 162 69.234 -25.399 54.342 1.00 73.11 C +ATOM 10757 C ARG F 162 69.048 -24.012 54.986 1.00 71.53 C +ATOM 10758 O ARG F 162 67.930 -23.501 55.069 1.00108.24 O +ATOM 10759 CB ARG F 162 69.186 -25.318 52.805 1.00 91.22 C +ATOM 10760 CG ARG F 162 67.863 -24.884 52.155 1.00 89.79 C +ATOM 10761 CD ARG F 162 68.099 -24.453 50.689 1.00 74.46 C +ATOM 10762 NE ARG F 162 66.927 -23.838 50.047 1.00 69.75 N +ATOM 10763 CZ ARG F 162 66.485 -24.068 48.802 1.00 78.33 C +ATOM 10764 NH1 ARG F 162 67.107 -24.886 47.949 1.00 91.73 N +ATOM 10765 NH2 ARG F 162 65.408 -23.413 48.362 1.00 76.28 N +ATOM 10766 N VAL F 163 70.173 -23.405 55.389 1.00 62.11 N +ATOM 10767 CA VAL F 163 70.195 -22.085 56.008 1.00 58.46 C +ATOM 10768 C VAL F 163 70.287 -21.031 54.952 1.00 46.55 C +ATOM 10769 O VAL F 163 71.235 -21.023 54.179 1.00 41.44 O +ATOM 10770 CB VAL F 163 71.417 -21.887 56.893 1.00 72.55 C +ATOM 10771 CG1 VAL F 163 71.416 -20.475 57.475 1.00 73.71 C +ATOM 10772 CG2 VAL F 163 71.461 -22.961 57.986 1.00 96.94 C +ATOM 10773 N VAL F 164 69.304 -20.134 54.961 1.00 39.34 N +ATOM 10774 CA VAL F 164 69.244 -19.035 54.052 1.00 44.49 C +ATOM 10775 C VAL F 164 69.432 -17.738 54.788 1.00 41.44 C +ATOM 10776 O VAL F 164 68.860 -17.534 55.843 1.00 35.04 O +ATOM 10777 CB VAL F 164 67.895 -18.956 53.370 1.00 61.84 C +ATOM 10778 CG1 VAL F 164 67.852 -17.753 52.416 1.00 96.48 C +ATOM 10779 CG2 VAL F 164 67.633 -20.225 52.589 1.00 77.61 C +ATOM 10780 N ASN F 165 70.254 -16.869 54.214 1.00 47.26 N +ATOM 10781 CA ASN F 165 70.549 -15.589 54.832 1.00 70.35 C +ATOM 10782 C ASN F 165 69.525 -14.565 54.414 1.00 88.93 C +ATOM 10783 O ASN F 165 69.403 -14.261 53.229 1.00 92.13 O +ATOM 10784 CB ASN F 165 71.951 -15.078 54.452 1.00 97.00 C +ATOM 10785 CG ASN F 165 72.369 -13.866 55.276 1.00 98.96 C +ATOM 10786 OD1 ASN F 165 71.676 -13.491 56.220 1.00 82.24 O +ATOM 10787 ND2 ASN F 165 73.443 -13.210 54.870 1.00100.59 N +ATOM 10788 N VAL F 166 68.805 -14.035 55.401 1.00101.75 N +ATOM 10789 CA VAL F 166 67.717 -13.111 55.158 1.00 80.22 C +ATOM 10790 C VAL F 166 68.256 -11.890 54.474 1.00 55.53 C +ATOM 10791 O VAL F 166 67.618 -11.352 53.583 1.00 66.09 O +ATOM 10792 CB VAL F 166 67.018 -12.720 56.481 1.00 83.45 C +ATOM 10793 CG1 VAL F 166 66.336 -11.361 56.369 1.00 90.85 C +ATOM 10794 CG2 VAL F 166 66.036 -13.827 56.898 1.00 82.98 C +ATOM 10795 N SER F 167 69.431 -11.475 54.885 1.00 48.51 N +ATOM 10796 CA SER F 167 69.956 -10.227 54.438 1.00 70.07 C +ATOM 10797 C SER F 167 70.373 -10.250 52.961 1.00 61.54 C +ATOM 10798 O SER F 167 70.662 -9.164 52.396 1.00 93.99 O +ATOM 10799 CB SER F 167 71.123 -9.806 55.351 1.00100.80 C +ATOM 10800 OG SER F 167 70.780 -9.989 56.723 1.00136.58 O +ATOM 10801 N THR F 168 70.466 -11.435 52.359 1.00 44.61 N +ATOM 10802 CA THR F 168 70.990 -11.537 50.990 1.00 55.60 C +ATOM 10803 C THR F 168 70.303 -12.546 50.121 1.00 60.23 C +ATOM 10804 O THR F 168 70.096 -12.344 48.911 1.00 85.53 O +ATOM 10805 CB THR F 168 72.466 -11.949 50.958 1.00 63.55 C +ATOM 10806 OG1 THR F 168 72.656 -13.102 51.772 1.00 67.91 O +ATOM 10807 CG2 THR F 168 73.373 -10.806 51.462 1.00 72.34 C +ATOM 10808 N GLY F 169 69.864 -13.622 50.734 1.00 70.31 N +ATOM 10809 CA GLY F 169 69.184 -14.645 49.964 1.00 80.61 C +ATOM 10810 C GLY F 169 70.184 -15.701 49.633 1.00103.95 C +ATOM 10811 O GLY F 169 69.811 -16.773 49.142 1.00157.54 O +ATOM 10812 N GLU F 170 71.470 -15.407 49.857 1.00106.20 N +ATOM 10813 CA GLU F 170 72.508 -16.454 49.782 1.00134.19 C +ATOM 10814 C GLU F 170 72.091 -17.619 50.693 1.00 96.58 C +ATOM 10815 O GLU F 170 71.750 -17.408 51.837 1.00 90.60 O +ATOM 10816 CB GLU F 170 73.889 -15.928 50.218 1.00139.60 C +ATOM 10817 CG GLU F 170 74.590 -15.065 49.178 1.00134.30 C +ATOM 10818 CD GLU F 170 75.390 -13.916 49.770 1.00159.44 C +ATOM 10819 OE1 GLU F 170 75.240 -13.629 50.980 1.00213.61 O +ATOM 10820 OE2 GLU F 170 76.118 -13.240 49.013 1.00168.44 O +ATOM 10821 N ILE F 171 72.042 -18.822 50.154 1.00 56.42 N +ATOM 10822 CA ILE F 171 71.990 -19.953 50.988 1.00 52.61 C +ATOM 10823 C ILE F 171 73.331 -20.085 51.679 1.00 70.50 C +ATOM 10824 O ILE F 171 74.386 -20.130 51.022 1.00127.39 O +ATOM 10825 CB ILE F 171 71.679 -21.179 50.166 1.00 63.30 C +ATOM 10826 CG1 ILE F 171 70.220 -21.113 49.684 1.00 70.83 C +ATOM 10827 CG2 ILE F 171 71.935 -22.437 50.985 1.00 69.05 C +ATOM 10828 CD1 ILE F 171 69.916 -22.082 48.566 1.00 81.84 C +ATOM 10829 N LEU F 172 73.323 -20.168 53.006 1.00 91.38 N +ATOM 10830 CA LEU F 172 74.577 -20.253 53.777 1.00103.30 C +ATOM 10831 C LEU F 172 75.016 -21.701 54.094 1.00118.77 C +ATOM 10832 O LEU F 172 76.178 -21.988 54.479 1.00 77.74 O +ATOM 10833 CB LEU F 172 74.471 -19.471 55.082 1.00 86.71 C +ATOM 10834 CG LEU F 172 74.417 -17.934 54.868 1.00108.90 C +ATOM 10835 CD1 LEU F 172 74.456 -17.075 56.150 1.00115.55 C +ATOM 10836 CD2 LEU F 172 75.407 -17.409 53.827 1.00 84.64 C +ATOM 10837 N SER F 173 74.087 -22.625 53.889 1.00144.40 N +ATOM 10838 CA SER F 173 74.390 -24.043 54.072 1.00143.48 C +ATOM 10839 C SER F 173 73.275 -24.920 53.527 1.00119.75 C +ATOM 10840 O SER F 173 72.107 -24.691 53.830 1.00178.02 O +ATOM 10841 CB SER F 173 74.571 -24.330 55.558 1.00152.01 C +ATOM 10842 OG SER F 173 74.507 -25.719 55.811 1.00116.23 O +ATOM 10843 N SER F 174 73.631 -25.938 52.753 1.00 80.57 N +ATOM 10844 CA SER F 174 72.677 -26.979 52.418 1.00 98.73 C +ATOM 10845 C SER F 174 73.203 -28.317 52.941 1.00104.75 C +ATOM 10846 O SER F 174 74.378 -28.632 52.751 1.00127.78 O +ATOM 10847 CB SER F 174 72.445 -27.026 50.897 1.00 93.07 C +ATOM 10848 OG SER F 174 71.338 -27.867 50.546 1.00109.40 O +ATOM 10849 N VAL F 175 72.320 -29.126 53.533 1.00 71.63 N +ATOM 10850 CA VAL F 175 72.684 -30.466 53.962 1.00 58.10 C +ATOM 10851 C VAL F 175 71.634 -31.516 53.582 1.00 83.85 C +ATOM 10852 O VAL F 175 70.438 -31.255 53.608 1.00110.19 O +ATOM 10853 CB VAL F 175 72.890 -30.504 55.479 1.00 64.06 C +ATOM 10854 CG1 VAL F 175 74.056 -29.601 55.868 1.00 93.53 C +ATOM 10855 CG2 VAL F 175 71.644 -30.073 56.221 1.00 53.06 C +ATOM 10856 N ASN F 176 72.095 -32.741 53.311 1.00116.87 N +ATOM 10857 CA ASN F 176 71.241 -33.831 52.790 1.00 99.85 C +ATOM 10858 C ASN F 176 71.333 -35.129 53.597 1.00 79.39 C +ATOM 10859 O ASN F 176 72.232 -35.922 53.356 1.00 92.81 O +ATOM 10860 CB ASN F 176 71.660 -34.106 51.332 1.00112.15 C +ATOM 10861 CG ASN F 176 70.784 -33.390 50.300 1.00127.34 C +ATOM 10862 OD1 ASN F 176 70.799 -33.689 49.065 1.00 77.64 O +ATOM 10863 ND2 ASN F 176 69.973 -32.473 50.804 1.00136.24 N +ATOM 10864 N THR F 177 70.436 -35.330 54.561 1.00 70.13 N +ATOM 10865 CA THR F 177 70.526 -36.480 55.471 1.00100.64 C +ATOM 10866 C THR F 177 69.575 -37.595 55.040 1.00 88.16 C +ATOM 10867 O THR F 177 68.685 -37.357 54.257 1.00 77.64 O +ATOM 10868 CB THR F 177 70.210 -36.116 56.937 1.00111.02 C +ATOM 10869 OG1 THR F 177 68.826 -35.800 57.053 1.00116.31 O +ATOM 10870 CG2 THR F 177 71.050 -34.926 57.424 1.00111.14 C +ATOM 10871 N SER F 178 69.838 -38.820 55.503 1.00141.36 N +ATOM 10872 CA SER F 178 69.112 -40.021 55.057 1.00161.31 C +ATOM 10873 C SER F 178 69.018 -41.050 56.174 1.00134.56 C +ATOM 10874 O SER F 178 69.870 -41.118 57.044 1.00149.84 O +ATOM 10875 CB SER F 178 69.776 -40.683 53.825 1.00159.54 C +ATOM 10876 OG SER F 178 69.244 -41.990 53.584 1.00 95.31 O +ATOM 10877 N LYS F 179 68.006 -41.898 56.097 1.00109.09 N +ATOM 10878 CA LYS F 179 67.718 -42.799 57.186 1.00125.97 C +ATOM 10879 C LYS F 179 66.890 -43.978 56.690 1.00127.51 C +ATOM 10880 O LYS F 179 66.033 -43.843 55.808 1.00158.74 O +ATOM 10881 CB LYS F 179 66.986 -42.045 58.304 1.00138.91 C +ATOM 10882 CG LYS F 179 67.349 -42.490 59.706 1.00148.24 C +ATOM 10883 CD LYS F 179 66.372 -43.540 60.202 1.00150.26 C +ATOM 10884 CE LYS F 179 66.831 -44.111 61.526 1.00169.20 C +ATOM 10885 NZ LYS F 179 66.076 -45.338 61.881 1.00191.49 N +ATOM 10886 N THR F 180 67.146 -45.134 57.279 1.00139.72 N +ATOM 10887 CA THR F 180 66.525 -46.365 56.842 1.00164.31 C +ATOM 10888 C THR F 180 65.471 -46.841 57.852 1.00148.40 C +ATOM 10889 O THR F 180 65.721 -46.903 59.058 1.00142.26 O +ATOM 10890 CB THR F 180 67.572 -47.479 56.577 1.00198.92 C +ATOM 10891 OG1 THR F 180 66.949 -48.767 56.708 1.00239.99 O +ATOM 10892 CG2 THR F 180 68.746 -47.378 57.532 1.00193.42 C +ATOM 10893 N ILE F 181 64.299 -47.205 57.336 1.00159.11 N +ATOM 10894 CA ILE F 181 63.211 -47.745 58.163 1.00172.30 C +ATOM 10895 C ILE F 181 63.148 -49.294 58.108 1.00198.47 C +ATOM 10896 O ILE F 181 62.924 -49.845 57.024 1.00152.15 O +ATOM 10897 CB ILE F 181 61.848 -47.139 57.730 1.00149.78 C +ATOM 10898 CG1 ILE F 181 61.936 -45.612 57.686 1.00125.66 C +ATOM 10899 CG2 ILE F 181 60.730 -47.551 58.674 1.00136.04 C +ATOM 10900 CD1 ILE F 181 61.671 -45.036 56.320 1.00144.92 C +ATOM 10901 N LEU F 182 63.351 -49.959 59.267 1.00212.98 N +ATOM 10902 CA LEU F 182 63.360 -51.462 59.393 1.00189.18 C +ATOM 10903 C LEU F 182 61.976 -52.024 59.669 1.00134.52 C +ATOM 10904 O LEU F 182 61.274 -51.568 60.575 1.00 75.79 O +ATOM 10905 CB LEU F 182 64.240 -52.035 60.591 1.00207.96 C +ATOM 10906 CG LEU F 182 65.744 -52.419 60.543 1.00227.44 C +ATOM 10907 CD1 LEU F 182 66.625 -51.277 60.041 1.00204.86 C +ATOM 10908 CD2 LEU F 182 66.215 -52.895 61.926 1.00221.03 C +ATOM 10909 N SER F 183 61.695 -53.139 59.011 1.00138.33 N +ATOM 10910 CA SER F 183 60.519 -53.945 59.315 1.00135.61 C +ATOM 10911 C SER F 183 60.857 -55.441 59.246 1.00179.32 C +ATOM 10912 O SER F 183 61.663 -55.864 58.409 1.00149.39 O +ATOM 10913 CB SER F 183 59.429 -53.635 58.313 1.00118.78 C +ATOM 10914 OG SER F 183 59.417 -52.264 57.983 1.00131.07 O +ATOM 10915 N TYR F 184 60.271 -56.231 60.151 1.00185.62 N +ATOM 10916 CA TYR F 184 60.470 -57.681 60.137 1.00141.33 C +ATOM 10917 C TYR F 184 59.287 -58.491 60.710 1.00133.05 C +ATOM 10918 O TYR F 184 58.501 -58.012 61.539 1.00 82.47 O +ATOM 10919 CB TYR F 184 61.781 -58.056 60.830 1.00107.16 C +ATOM 10920 CG TYR F 184 61.847 -57.620 62.278 1.00133.24 C +ATOM 10921 CD1 TYR F 184 61.273 -58.393 63.298 1.00144.77 C +ATOM 10922 CD2 TYR F 184 62.507 -56.457 62.640 1.00156.64 C +ATOM 10923 CE1 TYR F 184 61.340 -58.005 64.628 1.00119.39 C +ATOM 10924 CE2 TYR F 184 62.576 -56.057 63.964 1.00166.83 C +ATOM 10925 CZ TYR F 184 62.001 -56.842 64.953 1.00142.35 C +ATOM 10926 OH TYR F 184 62.059 -56.424 66.260 1.00132.52 O +ATOM 10927 N GLU F 185 59.187 -59.727 60.226 1.00145.66 N +ATOM 10928 CA GLU F 185 58.132 -60.660 60.598 1.00152.46 C +ATOM 10929 C GLU F 185 58.725 -62.019 60.941 1.00179.76 C +ATOM 10930 O GLU F 185 59.222 -62.729 60.071 1.00139.28 O +ATOM 10931 CB GLU F 185 57.108 -60.852 59.481 1.00160.35 C +ATOM 10932 CG GLU F 185 56.692 -59.601 58.743 1.00178.50 C +ATOM 10933 CD GLU F 185 55.533 -59.876 57.800 1.00205.42 C +ATOM 10934 OE1 GLU F 185 55.090 -61.051 57.713 1.00222.30 O +ATOM 10935 OE2 GLU F 185 55.028 -58.912 57.188 1.00203.61 O +ATOM 10936 N VAL F 186 58.614 -62.394 62.210 1.00199.38 N +ATOM 10937 CA VAL F 186 59.043 -63.704 62.688 1.00190.15 C +ATOM 10938 C VAL F 186 57.837 -64.631 62.895 1.00188.16 C +ATOM 10939 O VAL F 186 56.795 -64.188 63.378 1.00150.57 O +ATOM 10940 CB VAL F 186 59.813 -63.571 64.009 1.00169.13 C +ATOM 10941 CG1 VAL F 186 60.440 -64.900 64.392 1.00182.93 C +ATOM 10942 CG2 VAL F 186 60.880 -62.495 63.895 1.00173.61 C +ATOM 10943 N GLN F 187 57.977 -65.898 62.499 1.00162.84 N +ATOM 10944 CA GLN F 187 56.865 -66.839 62.545 1.00146.50 C +ATOM 10945 C GLN F 187 57.351 -68.250 62.792 1.00155.61 C +ATOM 10946 O GLN F 187 58.325 -68.690 62.188 1.00123.55 O +ATOM 10947 CB GLN F 187 56.098 -66.807 61.215 1.00160.16 C +ATOM 10948 CG GLN F 187 55.030 -65.736 61.098 1.00179.89 C +ATOM 10949 CD GLN F 187 54.679 -65.435 59.651 1.00191.52 C +ATOM 10950 OE1 GLN F 187 54.606 -66.345 58.822 1.00170.43 O +ATOM 10951 NE2 GLN F 187 54.458 -64.150 59.336 1.00187.98 N +ATOM 10952 N ALA F 188 56.619 -68.982 63.626 1.00183.99 N +ATOM 10953 CA ALA F 188 56.906 -70.397 63.855 1.00187.51 C +ATOM 10954 C ALA F 188 55.613 -71.207 63.987 1.00190.64 C +ATOM 10955 O ALA F 188 54.647 -70.735 64.564 1.00144.21 O +ATOM 10956 CB ALA F 188 57.772 -70.553 65.092 1.00156.78 C +ATOM 10957 N GLY F 189 55.595 -72.411 63.418 1.00187.42 N +ATOM 10958 CA GLY F 189 54.413 -73.267 63.460 1.00173.97 C +ATOM 10959 C GLY F 189 54.740 -74.749 63.547 1.00185.61 C +ATOM 10960 O GLY F 189 55.673 -75.230 62.904 1.00135.66 O +ATOM 10961 N VAL F 190 53.987 -75.469 64.375 1.00219.89 N +ATOM 10962 CA VAL F 190 54.155 -76.917 64.528 1.00226.53 C +ATOM 10963 C VAL F 190 52.898 -77.642 64.041 1.00228.08 C +ATOM 10964 O VAL F 190 51.780 -77.214 64.323 1.00189.60 O +ATOM 10965 CB VAL F 190 54.431 -77.304 65.995 1.00211.64 C +ATOM 10966 CG1 VAL F 190 54.852 -78.761 66.085 1.00193.96 C +ATOM 10967 CG2 VAL F 190 55.494 -76.393 66.609 1.00209.81 C +ATOM 10968 N PHE F 191 53.086 -78.711 63.272 1.00243.45 N +ATOM 10969 CA PHE F 191 51.979 -79.352 62.562 1.00247.87 C +ATOM 10970 C PHE F 191 52.055 -80.860 62.755 1.00220.91 C +ATOM 10971 O PHE F 191 53.109 -81.458 62.520 1.00259.78 O +ATOM 10972 CB PHE F 191 52.009 -78.974 61.062 1.00245.17 C +ATOM 10973 CG PHE F 191 50.687 -79.149 60.357 1.00248.06 C +ATOM 10974 CD1 PHE F 191 50.198 -80.413 60.068 1.00226.17 C +ATOM 10975 CD2 PHE F 191 49.938 -78.044 59.966 1.00255.05 C +ATOM 10976 CE1 PHE F 191 48.982 -80.577 59.419 1.00195.13 C +ATOM 10977 CE2 PHE F 191 48.718 -78.202 59.325 1.00229.61 C +ATOM 10978 CZ PHE F 191 48.239 -79.471 59.050 1.00193.31 C +ATOM 10979 N LEU F 200 47.122 -82.058 65.275 1.00253.01 N +ATOM 10980 CA LEU F 200 47.789 -80.991 66.022 1.00256.46 C +ATOM 10981 C LEU F 200 48.375 -79.931 65.095 1.00248.13 C +ATOM 10982 O LEU F 200 49.314 -80.207 64.344 1.00171.06 O +ATOM 10983 CB LEU F 200 48.915 -81.561 66.889 1.00233.72 C +ATOM 10984 CG LEU F 200 49.810 -80.496 67.549 1.00197.89 C +ATOM 10985 CD1 LEU F 200 49.414 -80.313 69.010 1.00174.17 C +ATOM 10986 CD2 LEU F 200 51.300 -80.802 67.408 1.00173.27 C +ATOM 10987 N GLU F 201 47.829 -78.718 65.179 1.00248.64 N +ATOM 10988 CA GLU F 201 48.508 -77.528 64.677 1.00217.17 C +ATOM 10989 C GLU F 201 48.729 -76.520 65.800 1.00199.07 C +ATOM 10990 O GLU F 201 47.929 -76.434 66.730 1.00128.15 O +ATOM 10991 CB GLU F 201 47.703 -76.873 63.556 1.00198.80 C +ATOM 10992 CG GLU F 201 48.546 -75.951 62.688 1.00193.01 C +ATOM 10993 CD GLU F 201 47.758 -75.297 61.564 1.00185.78 C +ATOM 10994 OE1 GLU F 201 47.059 -76.016 60.818 1.00204.30 O +ATOM 10995 OE2 GLU F 201 47.866 -74.063 61.406 1.00154.83 O +ATOM 10996 N GLY F 202 49.827 -75.773 65.716 1.00192.52 N +ATOM 10997 CA GLY F 202 50.099 -74.680 66.645 1.00168.66 C +ATOM 10998 C GLY F 202 51.002 -73.636 66.011 1.00146.42 C +ATOM 10999 O GLY F 202 52.080 -73.958 65.520 1.00105.85 O +ATOM 11000 N GLU F 203 50.575 -72.378 66.044 1.00146.39 N +ATOM 11001 CA GLU F 203 51.326 -71.306 65.403 1.00156.47 C +ATOM 11002 C GLU F 203 51.550 -70.087 66.303 1.00160.61 C +ATOM 11003 O GLU F 203 50.633 -69.619 66.986 1.00118.83 O +ATOM 11004 CB GLU F 203 50.616 -70.877 64.122 1.00193.19 C +ATOM 11005 CG GLU F 203 50.613 -71.960 63.046 1.00196.35 C +ATOM 11006 CD GLU F 203 50.016 -71.519 61.713 1.00219.08 C +ATOM 11007 OE1 GLU F 203 49.428 -70.409 61.651 1.00277.11 O +ATOM 11008 OE2 GLU F 203 50.092 -72.311 60.736 1.00162.68 O +ATOM 11009 N VAL F 204 52.769 -69.558 66.254 1.00172.99 N +ATOM 11010 CA VAL F 204 53.124 -68.283 66.875 1.00187.18 C +ATOM 11011 C VAL F 204 53.700 -67.336 65.816 1.00212.90 C +ATOM 11012 O VAL F 204 54.502 -67.745 64.976 1.00196.02 O +ATOM 11013 CB VAL F 204 54.139 -68.493 68.019 1.00140.05 C +ATOM 11014 CG1 VAL F 204 54.803 -67.184 68.439 1.00133.96 C +ATOM 11015 CG2 VAL F 204 53.444 -69.142 69.209 1.00123.60 C +ATOM 11016 N GLY F 205 53.273 -66.072 65.861 1.00206.84 N +ATOM 11017 CA GLY F 205 53.790 -65.047 64.964 1.00177.24 C +ATOM 11018 C GLY F 205 54.063 -63.723 65.667 1.00180.83 C +ATOM 11019 O GLY F 205 53.416 -63.397 66.662 1.00140.46 O +ATOM 11020 N TYR F 206 55.007 -62.948 65.130 1.00209.85 N +ATOM 11021 CA TYR F 206 55.288 -61.579 65.599 1.00226.16 C +ATOM 11022 C TYR F 206 55.770 -60.697 64.437 1.00215.98 C +ATOM 11023 O TYR F 206 56.530 -61.160 63.600 1.00193.09 O +ATOM 11024 CB TYR F 206 56.355 -61.606 66.703 1.00219.55 C +ATOM 11025 CG TYR F 206 56.766 -60.242 67.225 1.00217.71 C +ATOM 11026 CD1 TYR F 206 55.949 -59.533 68.110 1.00182.29 C +ATOM 11027 CD2 TYR F 206 57.982 -59.672 66.844 1.00198.81 C +ATOM 11028 CE1 TYR F 206 56.325 -58.289 68.585 1.00169.36 C +ATOM 11029 CE2 TYR F 206 58.366 -58.430 67.308 1.00181.04 C +ATOM 11030 CZ TYR F 206 57.540 -57.740 68.176 1.00192.39 C +ATOM 11031 OH TYR F 206 57.918 -56.477 68.585 1.00203.60 O +ATOM 11032 N THR F 207 55.351 -59.429 64.408 1.00169.11 N +ATOM 11033 CA THR F 207 55.804 -58.480 63.376 1.00143.62 C +ATOM 11034 C THR F 207 56.108 -57.086 63.945 1.00136.06 C +ATOM 11035 O THR F 207 55.384 -56.593 64.819 1.00107.22 O +ATOM 11036 CB THR F 207 54.747 -58.306 62.285 1.00149.34 C +ATOM 11037 OG1 THR F 207 53.551 -57.770 62.864 1.00115.87 O +ATOM 11038 CG2 THR F 207 54.421 -59.633 61.635 1.00162.76 C +ATOM 11039 N SER F 208 57.210 -56.474 63.495 1.00147.46 N +ATOM 11040 CA SER F 208 57.615 -55.153 64.022 1.00123.92 C +ATOM 11041 C SER F 208 58.065 -54.189 62.924 1.00147.82 C +ATOM 11042 O SER F 208 58.957 -54.511 62.122 1.00132.02 O +ATOM 11043 CB SER F 208 58.732 -55.289 65.060 1.00115.34 C +ATOM 11044 OG SER F 208 59.203 -54.017 65.476 1.00 78.93 O +ATOM 11045 N ASN F 209 57.464 -53.002 62.924 1.00149.09 N +ATOM 11046 CA ASN F 209 57.841 -51.929 62.009 1.00147.66 C +ATOM 11047 C ASN F 209 58.417 -50.750 62.762 1.00156.52 C +ATOM 11048 O ASN F 209 57.896 -50.370 63.806 1.00103.21 O +ATOM 11049 CB ASN F 209 56.624 -51.436 61.252 1.00132.82 C +ATOM 11050 CG ASN F 209 56.120 -52.444 60.263 1.00145.32 C +ATOM 11051 OD1 ASN F 209 56.616 -52.536 59.142 1.00172.60 O +ATOM 11052 ND2 ASN F 209 55.096 -53.179 60.653 1.00167.37 N +ATOM 11053 N GLU F 210 59.494 -50.168 62.227 1.00172.85 N +ATOM 11054 CA GLU F 210 59.983 -48.886 62.730 1.00134.35 C +ATOM 11055 C GLU F 210 58.944 -47.844 62.373 1.00122.97 C +ATOM 11056 O GLU F 210 58.341 -47.898 61.298 1.00132.20 O +ATOM 11057 CB GLU F 210 61.331 -48.521 62.100 1.00129.56 C +ATOM 11058 CG GLU F 210 62.357 -47.952 63.067 1.00132.33 C +ATOM 11059 CD GLU F 210 63.781 -47.990 62.505 1.00158.38 C +ATOM 11060 OE1 GLU F 210 64.108 -48.845 61.629 1.00130.06 O +ATOM 11061 OE2 GLU F 210 64.591 -47.129 62.921 1.00209.63 O +ATOM 11062 N PRO F 211 58.717 -46.894 63.271 1.00123.28 N +ATOM 11063 CA PRO F 211 57.854 -45.789 62.912 1.00144.34 C +ATOM 11064 C PRO F 211 58.555 -44.827 61.930 1.00161.03 C +ATOM 11065 O PRO F 211 59.662 -44.342 62.214 1.00121.23 O +ATOM 11066 CB PRO F 211 57.580 -45.108 64.255 1.00155.20 C +ATOM 11067 CG PRO F 211 57.927 -46.110 65.293 1.00156.92 C +ATOM 11068 CD PRO F 211 59.056 -46.891 64.696 1.00146.23 C +ATOM 11069 N VAL F 212 57.906 -44.566 60.787 1.00118.91 N +ATOM 11070 CA VAL F 212 58.429 -43.640 59.764 1.00 76.80 C +ATOM 11071 C VAL F 212 58.475 -42.225 60.329 1.00 60.85 C +ATOM 11072 O VAL F 212 59.456 -41.502 60.187 1.00 38.44 O +ATOM 11073 CB VAL F 212 57.532 -43.614 58.529 1.00104.68 C +ATOM 11074 CG1 VAL F 212 58.157 -42.749 57.445 1.00102.47 C +ATOM 11075 CG2 VAL F 212 57.252 -45.025 58.009 1.00140.19 C +ATOM 11076 N MET F 213 57.422 -41.902 61.063 1.00 58.81 N +ATOM 11077 CA MET F 213 57.397 -40.820 62.041 1.00 87.26 C +ATOM 11078 C MET F 213 58.742 -40.553 62.766 1.00 95.97 C +ATOM 11079 O MET F 213 59.247 -39.415 62.814 1.00116.23 O +ATOM 11080 CB MET F 213 56.308 -41.202 63.060 1.00 89.50 C +ATOM 11081 CG MET F 213 55.935 -40.183 64.107 1.00 95.74 C +ATOM 11082 SD MET F 213 54.624 -40.879 65.092 1.00102.65 S +ATOM 11083 CE MET F 213 55.566 -41.180 66.579 1.00160.22 C +ATOM 11084 N LEU F 214 59.303 -41.612 63.338 1.00133.65 N +ATOM 11085 CA LEU F 214 60.397 -41.517 64.315 1.00135.43 C +ATOM 11086 C LEU F 214 61.736 -41.476 63.592 1.00118.63 C +ATOM 11087 O LEU F 214 62.664 -40.791 64.030 1.00106.09 O +ATOM 11088 CB LEU F 214 60.372 -42.722 65.259 1.00113.98 C +ATOM 11089 CG LEU F 214 60.607 -42.476 66.753 1.00129.27 C +ATOM 11090 CD1 LEU F 214 59.568 -41.522 67.391 1.00136.26 C +ATOM 11091 CD2 LEU F 214 60.616 -43.829 67.463 1.00130.05 C +ATOM 11092 N CYS F 215 61.765 -42.078 62.415 1.00104.49 N +ATOM 11093 CA CYS F 215 62.913 -41.956 61.533 1.00117.48 C +ATOM 11094 C CYS F 215 63.041 -40.551 60.925 1.00115.38 C +ATOM 11095 O CYS F 215 64.161 -39.998 60.781 1.00 99.14 O +ATOM 11096 CB CYS F 215 62.777 -42.960 60.401 1.00158.18 C +ATOM 11097 SG CYS F 215 62.751 -44.658 60.974 1.00207.77 S +ATOM 11098 N LEU F 216 61.899 -39.996 60.501 1.00 89.79 N +ATOM 11099 CA LEU F 216 61.866 -38.628 60.010 1.00 82.37 C +ATOM 11100 C LEU F 216 62.429 -37.667 61.070 1.00 90.56 C +ATOM 11101 O LEU F 216 63.328 -36.865 60.806 1.00 94.43 O +ATOM 11102 CB LEU F 216 60.451 -38.226 59.648 1.00 63.12 C +ATOM 11103 CG LEU F 216 60.309 -36.782 59.166 1.00 68.98 C +ATOM 11104 CD1 LEU F 216 61.166 -36.471 57.940 1.00 77.00 C +ATOM 11105 CD2 LEU F 216 58.856 -36.492 58.818 1.00 88.70 C +ATOM 11106 N MET F 217 61.959 -37.828 62.297 1.00 96.46 N +ATOM 11107 CA MET F 217 62.398 -36.975 63.389 1.00 76.72 C +ATOM 11108 C MET F 217 63.901 -37.081 63.582 1.00 49.60 C +ATOM 11109 O MET F 217 64.597 -36.090 63.722 1.00 36.39 O +ATOM 11110 CB MET F 217 61.620 -37.308 64.687 1.00 91.83 C +ATOM 11111 CG MET F 217 61.132 -36.075 65.434 1.00112.40 C +ATOM 11112 SD MET F 217 62.488 -35.137 66.176 1.00151.73 S +ATOM 11113 CE MET F 217 61.675 -33.631 66.719 1.00161.72 C +ATOM 11114 N SER F 218 64.388 -38.304 63.616 1.00 61.86 N +ATOM 11115 CA SER F 218 65.818 -38.570 63.857 1.00 93.49 C +ATOM 11116 C SER F 218 66.653 -37.858 62.817 1.00 73.16 C +ATOM 11117 O SER F 218 67.637 -37.201 63.147 1.00 66.95 O +ATOM 11118 CB SER F 218 66.092 -40.100 63.823 1.00109.39 C +ATOM 11119 OG SER F 218 67.437 -40.402 64.222 1.00 57.09 O +ATOM 11120 N ALA F 219 66.244 -38.014 61.562 1.00 71.25 N +ATOM 11121 CA ALA F 219 67.041 -37.537 60.445 1.00 76.74 C +ATOM 11122 C ALA F 219 67.068 -35.986 60.442 1.00 72.64 C +ATOM 11123 O ALA F 219 68.076 -35.370 60.101 1.00 73.50 O +ATOM 11124 CB ALA F 219 66.492 -38.094 59.135 1.00 67.61 C +ATOM 11125 N ILE F 220 66.000 -35.376 60.913 1.00 61.59 N +ATOM 11126 CA ILE F 220 65.935 -33.923 60.967 1.00 78.99 C +ATOM 11127 C ILE F 220 66.854 -33.390 62.054 1.00 75.98 C +ATOM 11128 O ILE F 220 67.546 -32.402 61.864 1.00 87.88 O +ATOM 11129 CB ILE F 220 64.477 -33.432 61.222 1.00134.07 C +ATOM 11130 CG1 ILE F 220 63.598 -33.684 59.977 1.00127.61 C +ATOM 11131 CG2 ILE F 220 64.453 -31.951 61.604 1.00132.95 C +ATOM 11132 CD1 ILE F 220 62.100 -33.621 60.230 1.00 77.04 C +ATOM 11133 N GLU F 221 66.891 -34.074 63.189 1.00 88.12 N +ATOM 11134 CA GLU F 221 67.827 -33.718 64.266 1.00 99.46 C +ATOM 11135 C GLU F 221 69.267 -33.745 63.755 1.00 95.07 C +ATOM 11136 O GLU F 221 70.027 -32.787 63.929 1.00 87.05 O +ATOM 11137 CB GLU F 221 67.672 -34.695 65.454 1.00124.28 C +ATOM 11138 CG GLU F 221 66.403 -34.464 66.269 1.00139.55 C +ATOM 11139 CD GLU F 221 66.009 -35.635 67.150 1.00128.70 C +ATOM 11140 OE1 GLU F 221 66.225 -36.820 66.759 1.00120.57 O +ATOM 11141 OE2 GLU F 221 65.504 -35.365 68.258 1.00113.90 O +ATOM 11142 N THR F 222 69.635 -34.879 63.153 1.00 91.20 N +ATOM 11143 CA THR F 222 70.952 -35.078 62.541 1.00 78.68 C +ATOM 11144 C THR F 222 71.310 -33.928 61.602 1.00 79.28 C +ATOM 11145 O THR F 222 72.406 -33.376 61.675 1.00 74.80 O +ATOM 11146 CB THR F 222 70.973 -36.396 61.731 1.00 77.65 C +ATOM 11147 OG1 THR F 222 70.948 -37.519 62.629 1.00 66.95 O +ATOM 11148 CG2 THR F 222 72.194 -36.461 60.793 1.00 81.81 C +ATOM 11149 N GLY F 223 70.374 -33.585 60.720 1.00 99.09 N +ATOM 11150 CA GLY F 223 70.529 -32.441 59.823 1.00113.03 C +ATOM 11151 C GLY F 223 70.802 -31.134 60.557 1.00111.47 C +ATOM 11152 O GLY F 223 71.638 -30.343 60.125 1.00105.69 O +ATOM 11153 N VAL F 224 70.107 -30.916 61.679 1.00112.57 N +ATOM 11154 CA VAL F 224 70.296 -29.709 62.457 1.00112.22 C +ATOM 11155 C VAL F 224 71.731 -29.664 62.995 1.00124.33 C +ATOM 11156 O VAL F 224 72.388 -28.610 62.961 1.00107.84 O +ATOM 11157 CB VAL F 224 69.303 -29.611 63.627 1.00107.60 C +ATOM 11158 CG1 VAL F 224 69.668 -28.417 64.512 1.00136.39 C +ATOM 11159 CG2 VAL F 224 67.884 -29.488 63.115 1.00 77.40 C +ATOM 11160 N ILE F 225 72.227 -30.805 63.473 1.00109.68 N +ATOM 11161 CA ILE F 225 73.599 -30.873 63.963 1.00103.98 C +ATOM 11162 C ILE F 225 74.595 -30.519 62.857 1.00 99.66 C +ATOM 11163 O ILE F 225 75.436 -29.634 63.056 1.00 82.30 O +ATOM 11164 CB ILE F 225 73.938 -32.245 64.553 1.00 87.36 C +ATOM 11165 CG1 ILE F 225 73.148 -32.471 65.846 1.00 82.93 C +ATOM 11166 CG2 ILE F 225 75.428 -32.323 64.871 1.00106.51 C +ATOM 11167 CD1 ILE F 225 73.090 -33.921 66.266 1.00108.94 C +ATOM 11168 N PHE F 226 74.479 -31.183 61.702 1.00 98.56 N +ATOM 11169 CA PHE F 226 75.361 -30.907 60.551 1.00109.07 C +ATOM 11170 C PHE F 226 75.313 -29.443 60.144 1.00110.61 C +ATOM 11171 O PHE F 226 76.314 -28.881 59.710 1.00124.80 O +ATOM 11172 CB PHE F 226 75.002 -31.780 59.345 1.00111.80 C +ATOM 11173 CG PHE F 226 75.540 -33.198 59.427 1.00141.55 C +ATOM 11174 CD1 PHE F 226 76.912 -33.441 59.527 1.00154.99 C +ATOM 11175 CD2 PHE F 226 74.682 -34.296 59.361 1.00116.72 C +ATOM 11176 CE1 PHE F 226 77.406 -34.742 59.576 1.00123.64 C +ATOM 11177 CE2 PHE F 226 75.175 -35.594 59.391 1.00 86.75 C +ATOM 11178 CZ PHE F 226 76.531 -35.818 59.507 1.00 97.30 C +ATOM 11179 N LEU F 227 74.154 -28.813 60.325 1.00134.02 N +ATOM 11180 CA LEU F 227 73.992 -27.388 60.018 1.00135.13 C +ATOM 11181 C LEU F 227 74.751 -26.521 60.999 1.00137.73 C +ATOM 11182 O LEU F 227 75.454 -25.598 60.582 1.00181.88 O +ATOM 11183 CB LEU F 227 72.517 -27.012 60.043 1.00125.34 C +ATOM 11184 CG LEU F 227 71.698 -27.405 58.807 1.00161.79 C +ATOM 11185 CD1 LEU F 227 70.191 -27.306 58.971 1.00174.21 C +ATOM 11186 CD2 LEU F 227 72.124 -26.620 57.576 1.00132.33 C +ATOM 11187 N ILE F 228 74.670 -26.859 62.285 1.00106.78 N +ATOM 11188 CA ILE F 228 75.370 -26.094 63.315 1.00104.98 C +ATOM 11189 C ILE F 228 76.878 -26.235 63.151 1.00109.46 C +ATOM 11190 O ILE F 228 77.610 -25.238 63.135 1.00110.61 O +ATOM 11191 CB ILE F 228 75.005 -26.539 64.742 1.00 96.16 C +ATOM 11192 CG1 ILE F 228 73.522 -26.283 65.029 1.00 94.68 C +ATOM 11193 CG2 ILE F 228 75.836 -25.768 65.755 1.00 89.88 C +ATOM 11194 CD1 ILE F 228 72.976 -27.004 66.248 1.00 80.77 C +ATOM 11195 N ASN F 229 77.332 -27.469 62.965 1.00110.98 N +ATOM 11196 CA ASN F 229 78.757 -27.745 62.772 1.00125.60 C +ATOM 11197 C ASN F 229 79.308 -27.030 61.536 1.00122.23 C +ATOM 11198 O ASN F 229 80.360 -26.395 61.587 1.00139.27 O +ATOM 11199 CB ASN F 229 78.985 -29.259 62.654 1.00125.28 C +ATOM 11200 CG ASN F 229 80.429 -29.660 62.878 1.00132.99 C +ATOM 11201 OD1 ASN F 229 81.208 -28.929 63.501 1.00107.82 O +ATOM 11202 ND2 ASN F 229 80.800 -30.823 62.353 1.00154.38 N +ATOM 11203 N ASP F 230 78.557 -27.097 60.442 1.00123.34 N +ATOM 11204 CA ASP F 230 78.923 -26.419 59.209 1.00116.15 C +ATOM 11205 C ASP F 230 79.018 -24.910 59.444 1.00130.40 C +ATOM 11206 O ASP F 230 79.912 -24.246 58.930 1.00127.22 O +ATOM 11207 CB ASP F 230 77.896 -26.728 58.114 1.00131.53 C +ATOM 11208 CG ASP F 230 78.307 -26.185 56.765 1.00139.03 C +ATOM 11209 OD1 ASP F 230 79.262 -26.757 56.191 1.00 74.06 O +ATOM 11210 OD2 ASP F 230 77.663 -25.177 56.300 1.00227.29 O +ATOM 11211 N GLY F 231 78.066 -24.360 60.196 1.00142.89 N +ATOM 11212 CA GLY F 231 78.044 -22.926 60.470 1.00138.83 C +ATOM 11213 C GLY F 231 79.220 -22.508 61.335 1.00131.19 C +ATOM 11214 O GLY F 231 79.749 -21.395 61.185 1.00145.77 O +ATOM 11215 N ILE F 232 79.612 -23.390 62.258 1.00110.53 N +ATOM 11216 CA ILE F 232 80.783 -23.150 63.102 1.00104.26 C +ATOM 11217 C ILE F 232 82.032 -23.038 62.246 1.00108.53 C +ATOM 11218 O ILE F 232 82.783 -22.066 62.360 1.00106.58 O +ATOM 11219 CB ILE F 232 80.971 -24.267 64.138 1.00113.96 C +ATOM 11220 CG1 ILE F 232 79.907 -24.137 65.238 1.00126.83 C +ATOM 11221 CG2 ILE F 232 82.379 -24.226 64.740 1.00130.20 C +ATOM 11222 CD1 ILE F 232 79.723 -25.387 66.074 1.00130.68 C +ATOM 11223 N ASP F 233 82.216 -24.008 61.352 1.00124.78 N +ATOM 11224 CA ASP F 233 83.338 -24.005 60.408 1.00132.66 C +ATOM 11225 C ASP F 233 83.354 -22.728 59.565 1.00121.31 C +ATOM 11226 O ASP F 233 84.391 -22.076 59.437 1.00122.27 O +ATOM 11227 CB ASP F 233 83.273 -25.226 59.474 1.00149.65 C +ATOM 11228 CG ASP F 233 83.459 -26.554 60.211 1.00143.23 C +ATOM 11229 OD1 ASP F 233 83.453 -26.561 61.457 1.00132.91 O +ATOM 11230 OD2 ASP F 233 83.597 -27.595 59.528 1.00104.40 O +ATOM 11231 N ARG F 234 82.204 -22.365 59.005 1.00133.68 N +ATOM 11232 CA ARG F 234 82.127 -21.248 58.047 1.00159.09 C +ATOM 11233 C ARG F 234 82.029 -19.870 58.693 1.00143.51 C +ATOM 11234 O ARG F 234 81.996 -18.857 57.997 1.00113.77 O +ATOM 11235 CB ARG F 234 80.946 -21.454 57.104 1.00183.50 C +ATOM 11236 CG ARG F 234 81.211 -22.558 56.101 1.00192.40 C +ATOM 11237 CD ARG F 234 79.942 -23.135 55.517 1.00151.48 C +ATOM 11238 NE ARG F 234 80.301 -24.227 54.622 1.00121.05 N +ATOM 11239 CZ ARG F 234 79.989 -24.271 53.334 1.00134.04 C +ATOM 11240 NH1 ARG F 234 79.198 -23.333 52.806 1.00108.43 N +ATOM 11241 NH2 ARG F 234 80.407 -25.296 52.590 1.00140.08 N +ATOM 11242 N GLY F 235 82.015 -19.833 60.023 1.00141.51 N +ATOM 11243 CA GLY F 235 82.037 -18.573 60.756 1.00111.94 C +ATOM 11244 C GLY F 235 80.697 -17.869 60.751 1.00110.95 C +ATOM 11245 O GLY F 235 80.649 -16.634 60.757 1.00106.49 O +ATOM 11246 N LEU F 236 79.605 -18.634 60.720 1.00110.48 N +ATOM 11247 CA LEU F 236 78.281 -18.048 60.958 1.00123.77 C +ATOM 11248 C LEU F 236 78.129 -17.712 62.440 1.00111.90 C +ATOM 11249 O LEU F 236 77.723 -16.605 62.804 1.00103.43 O +ATOM 11250 CB LEU F 236 77.149 -18.990 60.527 1.00147.24 C +ATOM 11251 CG LEU F 236 76.741 -19.000 59.045 1.00160.47 C +ATOM 11252 CD1 LEU F 236 77.733 -19.818 58.231 1.00163.42 C +ATOM 11253 CD2 LEU F 236 75.331 -19.558 58.879 1.00142.80 C +ATOM 11254 N TRP F 237 78.473 -18.671 63.287 1.00108.23 N +ATOM 11255 CA TRP F 237 78.345 -18.508 64.731 1.00130.22 C +ATOM 11256 C TRP F 237 79.553 -19.130 65.443 1.00158.18 C +ATOM 11257 O TRP F 237 80.329 -19.874 64.834 1.00144.90 O +ATOM 11258 CB TRP F 237 77.038 -19.134 65.222 1.00118.40 C +ATOM 11259 CG TRP F 237 76.638 -20.335 64.441 1.00127.86 C +ATOM 11260 CD1 TRP F 237 77.292 -21.531 64.392 1.00150.66 C +ATOM 11261 CD2 TRP F 237 75.500 -20.467 63.577 1.00134.58 C +ATOM 11262 NE1 TRP F 237 76.636 -22.401 63.555 1.00160.24 N +ATOM 11263 CE2 TRP F 237 75.523 -21.781 63.051 1.00150.49 C +ATOM 11264 CE3 TRP F 237 74.469 -19.609 63.196 1.00118.42 C +ATOM 11265 CZ2 TRP F 237 74.563 -22.249 62.144 1.00130.91 C +ATOM 11266 CZ3 TRP F 237 73.508 -20.083 62.310 1.00121.71 C +ATOM 11267 CH2 TRP F 237 73.560 -21.394 61.800 1.00120.27 C +ATOM 11268 N ASP F 238 79.725 -18.792 66.720 1.00176.00 N +ATOM 11269 CA ASP F 238 80.931 -19.161 67.463 1.00171.00 C +ATOM 11270 C ASP F 238 80.611 -19.829 68.796 1.00155.22 C +ATOM 11271 O ASP F 238 79.624 -19.486 69.460 1.00113.16 O +ATOM 11272 CB ASP F 238 81.830 -17.939 67.701 1.00178.59 C +ATOM 11273 CG ASP F 238 82.229 -17.237 66.409 1.00166.48 C +ATOM 11274 OD1 ASP F 238 81.400 -16.467 65.889 1.00171.35 O +ATOM 11275 OD2 ASP F 238 83.361 -17.449 65.922 1.00116.42 O +ATOM 11276 N LEU F 239 81.497 -20.737 69.207 1.00156.95 N +ATOM 11277 CA LEU F 239 81.346 -21.462 70.461 1.00153.47 C +ATOM 11278 C LEU F 239 81.723 -20.582 71.645 1.00159.43 C +ATOM 11279 O LEU F 239 82.628 -19.745 71.557 1.00161.19 O +ATOM 11280 CB LEU F 239 82.228 -22.714 70.471 1.00168.07 C +ATOM 11281 CG LEU F 239 81.796 -23.943 69.675 1.00168.63 C +ATOM 11282 CD1 LEU F 239 82.754 -25.102 69.916 1.00180.94 C +ATOM 11283 CD2 LEU F 239 80.387 -24.351 70.045 1.00164.53 C +ATOM 11284 N GLN F 240 81.004 -20.764 72.750 1.00152.15 N +ATOM 11285 CA GLN F 240 81.381 -20.146 74.024 1.00134.84 C +ATOM 11286 C GLN F 240 82.824 -20.497 74.390 1.00141.70 C +ATOM 11287 O GLN F 240 83.659 -19.613 74.572 1.00153.78 O +ATOM 11288 CB GLN F 240 80.434 -20.614 75.137 1.00132.13 C +ATOM 11289 CG GLN F 240 80.619 -19.874 76.454 1.00117.67 C +ATOM 11290 CD GLN F 240 80.256 -18.405 76.338 1.00132.22 C +ATOM 11291 OE1 GLN F 240 79.074 -18.040 76.381 1.00158.23 O +ATOM 11292 NE2 GLN F 240 81.262 -17.556 76.143 1.00134.63 N +ATOM 11293 N ASN F 241 83.096 -21.798 74.464 1.00128.97 N +ATOM 11294 CA ASN F 241 84.421 -22.309 74.757 1.00106.09 C +ATOM 11295 C ASN F 241 85.097 -22.825 73.502 1.00142.63 C +ATOM 11296 O ASN F 241 84.712 -23.878 72.955 1.00179.42 O +ATOM 11297 CB ASN F 241 84.314 -23.440 75.753 1.00 90.00 C +ATOM 11298 CG ASN F 241 84.651 -22.997 77.147 1.00105.40 C +ATOM 11299 OD1 ASN F 241 85.746 -23.261 77.638 1.00119.97 O +ATOM 11300 ND2 ASN F 241 83.719 -22.309 77.801 1.00132.93 N +ATOM 11301 N LYS F 242 86.130 -22.113 73.059 1.00143.28 N +ATOM 11302 CA LYS F 242 86.872 -22.519 71.863 1.00157.62 C +ATOM 11303 C LYS F 242 87.587 -23.848 72.114 1.00166.03 C +ATOM 11304 O LYS F 242 87.828 -24.626 71.181 1.00151.21 O +ATOM 11305 CB LYS F 242 87.870 -21.433 71.453 1.00161.66 C +ATOM 11306 CG LYS F 242 87.263 -20.036 71.386 1.00166.47 C +ATOM 11307 CD LYS F 242 87.499 -19.370 70.040 1.00160.51 C +ATOM 11308 CE LYS F 242 86.222 -18.736 69.510 1.00154.57 C +ATOM 11309 NZ LYS F 242 86.449 -17.943 68.272 1.00159.41 N +ATOM 11310 N ALA F 243 87.861 -24.109 73.395 1.00192.42 N +ATOM 11311 CA ALA F 243 88.406 -25.384 73.871 1.00202.15 C +ATOM 11312 C ALA F 243 87.461 -26.548 73.593 1.00197.90 C +ATOM 11313 O ALA F 243 87.891 -27.704 73.594 1.00222.87 O +ATOM 11314 CB ALA F 243 88.698 -25.308 75.367 1.00198.53 C +ATOM 11315 N GLU F 244 86.180 -26.251 73.363 1.00178.36 N +ATOM 11316 CA GLU F 244 85.200 -27.307 73.133 1.00150.75 C +ATOM 11317 C GLU F 244 85.024 -27.629 71.655 1.00140.94 C +ATOM 11318 O GLU F 244 84.098 -28.335 71.301 1.00102.48 O +ATOM 11319 CB GLU F 244 83.852 -26.935 73.750 1.00157.52 C +ATOM 11320 CG GLU F 244 83.822 -27.016 75.262 1.00168.13 C +ATOM 11321 CD GLU F 244 82.413 -26.910 75.819 1.00177.63 C +ATOM 11322 OE1 GLU F 244 81.884 -25.770 75.887 1.00146.19 O +ATOM 11323 OE2 GLU F 244 81.869 -27.963 76.247 1.00137.84 O +ATOM 11324 N ARG F 245 85.898 -27.100 70.797 1.00158.28 N +ATOM 11325 CA ARG F 245 85.881 -27.452 69.377 1.00162.70 C +ATOM 11326 C ARG F 245 86.022 -28.955 69.137 1.00182.37 C +ATOM 11327 O ARG F 245 85.406 -29.488 68.215 1.00199.39 O +ATOM 11328 CB ARG F 245 86.979 -26.739 68.604 1.00162.48 C +ATOM 11329 CG ARG F 245 86.873 -26.932 67.089 1.00180.01 C +ATOM 11330 CD ARG F 245 87.922 -26.123 66.296 1.00185.19 C +ATOM 11331 NE ARG F 245 87.379 -24.865 65.774 1.00177.91 N +ATOM 11332 CZ ARG F 245 86.501 -24.774 64.774 1.00170.06 C +ATOM 11333 NH1 ARG F 245 86.042 -25.863 64.185 1.00176.54 N +ATOM 11334 NH2 ARG F 245 86.052 -23.591 64.375 1.00150.14 N +ATOM 11335 N GLN F 246 86.832 -29.631 69.953 1.00181.24 N +ATOM 11336 CA GLN F 246 87.079 -31.066 69.765 1.00160.48 C +ATOM 11337 C GLN F 246 86.110 -31.919 70.586 1.00147.39 C +ATOM 11338 O GLN F 246 86.389 -33.077 70.875 1.00133.74 O +ATOM 11339 CB GLN F 246 88.528 -31.426 70.108 1.00155.24 C +ATOM 11340 CG GLN F 246 89.554 -30.910 69.115 1.00170.34 C +ATOM 11341 CD GLN F 246 89.796 -29.424 69.264 1.00202.88 C +ATOM 11342 OE1 GLN F 246 89.962 -28.917 70.379 1.00238.04 O +ATOM 11343 NE2 GLN F 246 89.854 -28.718 68.140 1.00230.11 N +ATOM 11344 N ASN F 247 84.975 -31.333 70.957 1.00139.66 N +ATOM 11345 CA ASN F 247 83.844 -32.072 71.519 1.00138.28 C +ATOM 11346 C ASN F 247 83.603 -33.394 70.784 1.00145.80 C +ATOM 11347 O ASN F 247 83.655 -33.437 69.552 1.00153.17 O +ATOM 11348 CB ASN F 247 82.585 -31.208 71.420 1.00155.00 C +ATOM 11349 CG ASN F 247 81.551 -31.550 72.465 1.00164.57 C +ATOM 11350 OD1 ASN F 247 80.502 -32.127 72.159 1.00157.12 O +ATOM 11351 ND2 ASN F 247 81.837 -31.187 73.710 1.00181.61 N +ATOM 11352 N ASP F 248 83.322 -34.460 71.540 1.00155.19 N +ATOM 11353 CA ASP F 248 83.112 -35.806 70.966 1.00171.08 C +ATOM 11354 C ASP F 248 82.078 -35.795 69.838 1.00174.08 C +ATOM 11355 O ASP F 248 82.283 -36.375 68.764 1.00177.65 O +ATOM 11356 CB ASP F 248 82.632 -36.792 72.042 1.00174.52 C +ATOM 11357 CG ASP F 248 83.714 -37.153 73.039 1.00195.17 C +ATOM 11358 OD1 ASP F 248 84.890 -37.300 72.637 1.00202.10 O +ATOM 11359 OD2 ASP F 248 83.383 -37.306 74.233 1.00231.42 O +ATOM 11360 N ILE F 249 80.957 -35.138 70.106 1.00163.29 N +ATOM 11361 CA ILE F 249 79.852 -35.085 69.173 1.00143.99 C +ATOM 11362 C ILE F 249 80.263 -34.308 67.919 1.00134.53 C +ATOM 11363 O ILE F 249 80.078 -34.778 66.786 1.00159.36 O +ATOM 11364 CB ILE F 249 78.620 -34.430 69.835 1.00157.74 C +ATOM 11365 CG1 ILE F 249 78.144 -35.270 71.033 1.00123.70 C +ATOM 11366 CG2 ILE F 249 77.486 -34.293 68.828 1.00206.69 C +ATOM 11367 CD1 ILE F 249 77.282 -34.515 72.027 1.00 97.90 C +ATOM 11368 N LEU F 250 80.827 -33.121 68.127 1.00123.92 N +ATOM 11369 CA LEU F 250 81.221 -32.250 67.019 1.00140.48 C +ATOM 11370 C LEU F 250 82.246 -32.897 66.081 1.00154.95 C +ATOM 11371 O LEU F 250 82.172 -32.722 64.858 1.00132.01 O +ATOM 11372 CB LEU F 250 81.774 -30.927 67.544 1.00127.35 C +ATOM 11373 CG LEU F 250 80.714 -29.909 67.971 1.00136.28 C +ATOM 11374 CD1 LEU F 250 81.327 -28.750 68.736 1.00148.34 C +ATOM 11375 CD2 LEU F 250 79.970 -29.384 66.755 1.00158.32 C +ATOM 11376 N VAL F 251 83.182 -33.650 66.653 1.00169.94 N +ATOM 11377 CA VAL F 251 84.188 -34.351 65.847 1.00164.62 C +ATOM 11378 C VAL F 251 83.614 -35.603 65.181 1.00150.96 C +ATOM 11379 O VAL F 251 84.118 -36.049 64.148 1.00142.67 O +ATOM 11380 CB VAL F 251 85.441 -34.732 66.671 1.00146.71 C +ATOM 11381 CG1 VAL F 251 86.031 -33.497 67.345 1.00137.44 C +ATOM 11382 CG2 VAL F 251 85.126 -35.828 67.687 1.00133.40 C +ATOM 11383 N LYS F 252 82.571 -36.168 65.779 1.00130.75 N +ATOM 11384 CA LYS F 252 81.875 -37.303 65.185 1.00131.57 C +ATOM 11385 C LYS F 252 81.164 -36.891 63.885 1.00143.77 C +ATOM 11386 O LYS F 252 81.303 -37.554 62.849 1.00141.60 O +ATOM 11387 CB LYS F 252 80.881 -37.862 66.203 1.00140.51 C +ATOM 11388 CG LYS F 252 80.050 -39.040 65.723 1.00138.94 C +ATOM 11389 CD LYS F 252 79.081 -39.484 66.817 1.00129.03 C +ATOM 11390 CE LYS F 252 77.670 -39.680 66.275 1.00121.85 C +ATOM 11391 NZ LYS F 252 76.668 -39.857 67.354 1.00130.43 N +ATOM 11392 N TYR F 253 80.461 -35.757 63.927 1.00158.88 N +ATOM 11393 CA TYR F 253 79.730 -35.239 62.756 1.00144.05 C +ATOM 11394 C TYR F 253 80.668 -34.572 61.759 1.00168.92 C +ATOM 11395 O TYR F 253 80.441 -34.636 60.548 1.00148.76 O +ATOM 11396 CB TYR F 253 78.624 -34.269 63.182 1.00123.08 C +ATOM 11397 CG TYR F 253 77.469 -34.998 63.854 1.00147.58 C +ATOM 11398 CD1 TYR F 253 76.461 -35.601 63.099 1.00136.19 C +ATOM 11399 CD2 TYR F 253 77.424 -35.155 65.247 1.00154.21 C +ATOM 11400 CE1 TYR F 253 75.438 -36.308 63.717 1.00132.94 C +ATOM 11401 CE2 TYR F 253 76.395 -35.861 65.874 1.00110.53 C +ATOM 11402 CZ TYR F 253 75.417 -36.446 65.107 1.00116.50 C +ATOM 11403 OH TYR F 253 74.362 -37.084 65.698 1.00 93.21 O +ATOM 11404 N ARG F 254 81.742 -33.974 62.275 1.00172.85 N +ATOM 11405 CA ARG F 254 82.849 -33.505 61.435 1.00146.88 C +ATOM 11406 C ARG F 254 83.458 -34.659 60.625 1.00124.90 C +ATOM 11407 O ARG F 254 83.746 -34.505 59.436 1.00 97.87 O +ATOM 11408 CB ARG F 254 83.946 -32.872 62.296 1.00155.60 C +ATOM 11409 CG ARG F 254 85.065 -32.248 61.479 1.00179.27 C +ATOM 11410 CD ARG F 254 85.927 -31.288 62.284 1.00167.09 C +ATOM 11411 NE ARG F 254 85.211 -30.097 62.728 1.00175.63 N +ATOM 11412 CZ ARG F 254 84.825 -29.854 63.976 1.00172.62 C +ATOM 11413 NH1 ARG F 254 85.076 -30.717 64.946 1.00168.02 N +ATOM 11414 NH2 ARG F 254 84.169 -28.729 64.254 1.00179.23 N +ATOM 11415 N HIS F 255 83.602 -35.818 61.275 1.00108.12 N +ATOM 11416 CA HIS F 255 84.113 -37.018 60.624 1.00124.47 C +ATOM 11417 C HIS F 255 83.175 -37.585 59.546 1.00159.47 C +ATOM 11418 O HIS F 255 83.636 -38.114 58.535 1.00193.15 O +ATOM 11419 CB HIS F 255 84.434 -38.103 61.662 1.00151.98 C +ATOM 11420 CG HIS F 255 85.899 -38.268 61.913 1.00197.41 C +ATOM 11421 ND1 HIS F 255 86.633 -37.357 62.639 1.00220.59 N +ATOM 11422 CD2 HIS F 255 86.778 -39.207 61.487 1.00213.73 C +ATOM 11423 CE1 HIS F 255 87.897 -37.744 62.677 1.00209.56 C +ATOM 11424 NE2 HIS F 255 88.012 -38.861 61.983 1.00209.34 N +ATOM 11425 N MET F 256 81.863 -37.500 59.760 1.00153.10 N +ATOM 11426 CA MET F 256 80.911 -38.014 58.769 1.00112.43 C +ATOM 11427 C MET F 256 80.968 -37.191 57.468 1.00128.97 C +ATOM 11428 O MET F 256 80.607 -37.698 56.401 1.00113.66 O +ATOM 11429 CB MET F 256 79.494 -38.057 59.358 1.00131.81 C +ATOM 11430 CG MET F 256 79.401 -38.828 60.673 1.00150.58 C +ATOM 11431 SD MET F 256 77.749 -39.380 61.153 1.00181.45 S +ATOM 11432 CE MET F 256 77.454 -40.632 59.902 1.00179.54 C +ATOM 11433 N SER F 257 81.413 -35.926 57.569 1.00147.43 N +ATOM 11434 CA SER F 257 81.592 -35.030 56.398 1.00117.58 C +ATOM 11435 C SER F 257 82.838 -35.355 55.579 1.00107.49 C +ATOM 11436 O SER F 257 82.815 -36.242 54.735 1.00 67.13 O +ATOM 11437 CB SER F 257 81.673 -33.565 56.845 1.00 90.24 C +ATOM 11438 OG SER F 257 80.694 -33.282 57.833 1.00 67.61 O +TER 11439 SER F 257 +ATOM 11440 N LEU G 2 56.382 -54.429 76.312 1.00123.50 N +ATOM 11441 CA LEU G 2 56.639 -54.340 74.831 1.00141.09 C +ATOM 11442 C LEU G 2 55.311 -54.164 74.049 1.00162.18 C +ATOM 11443 O LEU G 2 54.835 -55.080 73.347 1.00144.47 O +ATOM 11444 CB LEU G 2 57.437 -55.556 74.338 1.00138.84 C +ATOM 11445 CG LEU G 2 58.853 -55.814 74.915 1.00136.44 C +ATOM 11446 CD1 LEU G 2 59.427 -57.086 74.300 1.00128.56 C +ATOM 11447 CD2 LEU G 2 59.833 -54.648 74.740 1.00117.20 C +ATOM 11448 N THR G 3 54.656 -53.037 74.341 1.00192.06 N +ATOM 11449 CA THR G 3 53.540 -52.476 73.558 1.00166.90 C +ATOM 11450 C THR G 3 53.650 -50.931 73.490 1.00134.21 C +ATOM 11451 O THR G 3 52.840 -50.249 72.863 1.00 81.39 O +ATOM 11452 CB THR G 3 52.161 -52.836 74.165 1.00158.78 C +ATOM 11453 OG1 THR G 3 51.992 -52.156 75.422 1.00136.98 O +ATOM 11454 CG2 THR G 3 51.999 -54.359 74.326 1.00120.11 C +ATOM 11455 N ALA G 4 54.636 -50.390 74.188 1.00129.53 N +ATOM 11456 CA ALA G 4 55.180 -49.079 73.861 1.00120.09 C +ATOM 11457 C ALA G 4 56.011 -49.197 72.554 1.00 92.66 C +ATOM 11458 O ALA G 4 56.022 -50.233 71.908 1.00 71.29 O +ATOM 11459 CB ALA G 4 56.006 -48.554 75.042 1.00121.46 C +ATOM 11460 N PRO G 5 56.681 -48.127 72.131 1.00 84.68 N +ATOM 11461 CA PRO G 5 57.159 -48.279 70.768 1.00 76.33 C +ATOM 11462 C PRO G 5 58.405 -49.176 70.669 1.00 80.19 C +ATOM 11463 O PRO G 5 59.070 -49.429 71.667 1.00 75.26 O +ATOM 11464 CB PRO G 5 57.442 -46.814 70.349 1.00 90.55 C +ATOM 11465 CG PRO G 5 57.740 -46.066 71.628 1.00 93.51 C +ATOM 11466 CD PRO G 5 57.158 -46.874 72.772 1.00100.58 C +ATOM 11467 N PRO G 6 58.818 -49.509 69.451 1.00 73.72 N +ATOM 11468 CA PRO G 6 60.194 -49.951 69.160 1.00 70.95 C +ATOM 11469 C PRO G 6 61.271 -48.842 69.112 1.00 70.29 C +ATOM 11470 O PRO G 6 60.985 -47.714 68.787 1.00 63.45 O +ATOM 11471 CB PRO G 6 60.071 -50.618 67.796 1.00 70.80 C +ATOM 11472 CG PRO G 6 58.824 -50.080 67.195 1.00 80.61 C +ATOM 11473 CD PRO G 6 57.961 -49.475 68.265 1.00 70.24 C +ATOM 11474 N LYS G 7 62.513 -49.188 69.418 1.00 98.25 N +ATOM 11475 CA LYS G 7 63.617 -48.213 69.446 1.00127.80 C +ATOM 11476 C LYS G 7 64.412 -48.190 68.136 1.00129.07 C +ATOM 11477 O LYS G 7 64.222 -49.063 67.281 1.00 98.11 O +ATOM 11478 CB LYS G 7 64.554 -48.496 70.634 1.00158.78 C +ATOM 11479 CG LYS G 7 63.946 -48.215 71.993 1.00179.90 C +ATOM 11480 CD LYS G 7 63.558 -49.484 72.756 1.00170.53 C +ATOM 11481 CE LYS G 7 63.254 -49.164 74.208 1.00156.16 C +ATOM 11482 NZ LYS G 7 62.267 -50.107 74.792 1.00137.06 N +ATOM 11483 N GLU G 8 65.322 -47.216 68.025 1.00131.53 N +ATOM 11484 CA GLU G 8 66.011 -46.908 66.769 1.00149.35 C +ATOM 11485 C GLU G 8 66.850 -48.069 66.232 1.00125.94 C +ATOM 11486 O GLU G 8 67.843 -48.458 66.832 1.00126.97 O +ATOM 11487 CB GLU G 8 66.878 -45.596 66.879 1.00186.39 C +ATOM 11488 CG GLU G 8 68.247 -45.699 67.528 1.00203.33 C +ATOM 11489 CD GLU G 8 69.057 -44.401 67.456 1.00202.32 C +ATOM 11490 OE1 GLU G 8 69.245 -43.834 66.364 1.00191.38 O +ATOM 11491 OE2 GLU G 8 69.562 -43.952 68.490 1.00167.07 O +ATOM 11492 N ALA G 9 66.454 -48.574 65.065 1.00121.95 N +ATOM 11493 CA ALA G 9 67.261 -49.471 64.259 1.00106.32 C +ATOM 11494 C ALA G 9 67.958 -48.720 63.101 1.00113.82 C +ATOM 11495 O ALA G 9 67.314 -48.298 62.131 1.00134.99 O +ATOM 11496 CB ALA G 9 66.380 -50.577 63.702 1.00 98.35 C +ATOM 11497 N ALA G 10 69.280 -48.598 63.212 1.00113.53 N +ATOM 11498 CA ALA G 10 70.138 -47.850 62.271 1.00114.90 C +ATOM 11499 C ALA G 10 70.181 -46.379 62.638 1.00113.73 C +ATOM 11500 O ALA G 10 69.293 -45.888 63.346 1.00 77.09 O +ATOM 11501 CB ALA G 10 69.707 -48.037 60.813 1.00125.76 C +ATOM 11502 N ARG G 11 71.221 -45.690 62.153 1.00131.33 N +ATOM 11503 CA ARG G 11 71.396 -44.254 62.414 1.00132.84 C +ATOM 11504 C ARG G 11 71.186 -43.398 61.148 1.00113.71 C +ATOM 11505 O ARG G 11 71.352 -43.861 60.002 1.00123.42 O +ATOM 11506 CB ARG G 11 72.703 -43.942 63.142 1.00124.68 C +ATOM 11507 CG ARG G 11 72.657 -44.199 64.648 1.00139.02 C +ATOM 11508 CD ARG G 11 74.014 -44.212 65.311 1.00159.38 C +ATOM 11509 NE ARG G 11 73.861 -44.212 66.765 1.00178.27 N +ATOM 11510 CZ ARG G 11 74.877 -44.315 67.616 1.00199.58 C +ATOM 11511 NH1 ARG G 11 76.120 -44.390 67.161 1.00215.34 N +ATOM 11512 NH2 ARG G 11 74.651 -44.326 68.921 1.00189.87 N +ATOM 11513 N PRO G 12 70.698 -42.170 61.337 1.00 97.79 N +ATOM 11514 CA PRO G 12 70.705 -41.261 60.217 1.00101.43 C +ATOM 11515 C PRO G 12 72.158 -40.988 59.794 1.00 99.62 C +ATOM 11516 O PRO G 12 72.934 -40.419 60.557 1.00140.27 O +ATOM 11517 CB PRO G 12 70.033 -39.977 60.776 1.00106.48 C +ATOM 11518 CG PRO G 12 69.393 -40.362 62.066 1.00 94.25 C +ATOM 11519 CD PRO G 12 70.222 -41.519 62.571 1.00116.41 C +ATOM 11520 N THR G 13 72.503 -41.393 58.589 1.00 80.92 N +ATOM 11521 CA THR G 13 73.702 -40.916 57.932 1.00 85.50 C +ATOM 11522 C THR G 13 73.395 -39.674 57.080 1.00 96.45 C +ATOM 11523 O THR G 13 72.248 -39.452 56.707 1.00158.25 O +ATOM 11524 CB THR G 13 74.253 -42.030 57.032 1.00 93.63 C +ATOM 11525 OG1 THR G 13 75.549 -41.668 56.546 1.00 87.70 O +ATOM 11526 CG2 THR G 13 73.294 -42.336 55.828 1.00 91.07 C +ATOM 11527 N LEU G 14 74.403 -38.897 56.701 1.00105.30 N +ATOM 11528 CA LEU G 14 74.164 -37.907 55.641 1.00106.18 C +ATOM 11529 C LEU G 14 74.048 -38.620 54.276 1.00106.45 C +ATOM 11530 O LEU G 14 74.436 -39.770 54.158 1.00 93.51 O +ATOM 11531 CB LEU G 14 75.188 -36.773 55.634 1.00114.16 C +ATOM 11532 CG LEU G 14 76.666 -37.127 55.564 1.00121.32 C +ATOM 11533 CD1 LEU G 14 77.437 -36.067 54.786 1.00140.04 C +ATOM 11534 CD2 LEU G 14 77.202 -37.236 56.971 1.00 95.48 C +ATOM 11535 N MET G 15 73.416 -37.989 53.289 1.00132.14 N +ATOM 11536 CA MET G 15 72.746 -38.741 52.204 1.00137.64 C +ATOM 11537 C MET G 15 73.765 -39.384 51.263 1.00120.60 C +ATOM 11538 O MET G 15 74.636 -38.707 50.732 1.00 80.64 O +ATOM 11539 CB MET G 15 71.765 -37.865 51.408 1.00126.24 C +ATOM 11540 CG MET G 15 70.610 -38.662 50.827 1.00 99.51 C +ATOM 11541 SD MET G 15 70.011 -38.322 49.181 1.00110.96 S +ATOM 11542 CE MET G 15 71.225 -37.260 48.373 1.00 83.20 C +ATOM 11543 N PRO G 16 73.688 -40.716 51.118 1.00104.99 N +ATOM 11544 CA PRO G 16 74.699 -41.524 50.433 1.00108.31 C +ATOM 11545 C PRO G 16 74.827 -41.210 48.948 1.00 94.80 C +ATOM 11546 O PRO G 16 74.328 -41.946 48.100 1.00122.67 O +ATOM 11547 CB PRO G 16 74.213 -42.964 50.664 1.00121.20 C +ATOM 11548 CG PRO G 16 72.755 -42.822 50.917 1.00126.53 C +ATOM 11549 CD PRO G 16 72.614 -41.551 51.683 1.00 99.24 C +ATOM 11550 N ARG G 17 75.585 -40.173 48.640 1.00118.76 N +ATOM 11551 CA ARG G 17 75.961 -39.885 47.264 1.00151.73 C +ATOM 11552 C ARG G 17 77.210 -40.693 46.866 1.00119.19 C +ATOM 11553 O ARG G 17 78.095 -40.857 47.692 1.00127.72 O +ATOM 11554 CB ARG G 17 76.177 -38.368 47.112 1.00154.66 C +ATOM 11555 CG ARG G 17 74.889 -37.604 46.824 1.00155.58 C +ATOM 11556 CD ARG G 17 75.006 -36.119 47.094 1.00155.25 C +ATOM 11557 NE ARG G 17 74.926 -35.823 48.519 1.00139.68 N +ATOM 11558 CZ ARG G 17 75.145 -34.619 49.038 1.00 93.17 C +ATOM 11559 NH1 ARG G 17 75.471 -33.604 48.232 1.00 75.12 N +ATOM 11560 NH2 ARG G 17 75.033 -34.428 50.350 1.00 62.68 N +ATOM 11561 N ALA G 18 77.304 -41.122 45.603 1.00 83.29 N +ATOM 11562 CA ALA G 18 78.466 -41.849 45.137 1.00 93.31 C +ATOM 11563 C ALA G 18 79.359 -41.064 44.135 1.00110.99 C +ATOM 11564 O ALA G 18 80.007 -40.065 44.511 1.00150.57 O +ATOM 11565 CB ALA G 18 78.035 -43.171 44.558 1.00 96.29 C +ATOM 11566 N GLN G 19 79.524 -41.591 42.923 1.00123.45 N +ATOM 11567 CA GLN G 19 80.702 -41.264 42.093 1.00171.23 C +ATOM 11568 C GLN G 19 80.603 -39.848 41.554 1.00165.09 C +ATOM 11569 O GLN G 19 81.559 -39.048 41.632 1.00194.73 O +ATOM 11570 CB GLN G 19 80.831 -42.248 40.919 1.00207.77 C +ATOM 11571 CG GLN G 19 82.074 -42.052 40.056 1.00207.23 C +ATOM 11572 CD GLN G 19 83.351 -42.076 40.879 1.00213.48 C +ATOM 11573 OE1 GLN G 19 83.736 -43.115 41.420 1.00226.36 O +ATOM 11574 NE2 GLN G 19 84.019 -40.933 40.975 1.00213.15 N +ATOM 11575 N SER G 20 79.439 -39.560 40.988 1.00117.48 N +ATOM 11576 CA SER G 20 79.111 -38.235 40.535 1.00110.02 C +ATOM 11577 C SER G 20 79.555 -37.185 41.572 1.00123.08 C +ATOM 11578 O SER G 20 80.189 -36.181 41.229 1.00100.45 O +ATOM 11579 CB SER G 20 77.600 -38.174 40.302 1.00125.60 C +ATOM 11580 OG SER G 20 77.165 -39.250 39.480 1.00 84.87 O +ATOM 11581 N TYR G 21 79.169 -37.399 42.832 1.00130.92 N +ATOM 11582 CA TYR G 21 79.521 -36.492 43.931 1.00134.77 C +ATOM 11583 C TYR G 21 81.035 -36.299 44.030 1.00128.73 C +ATOM 11584 O TYR G 21 81.520 -35.175 44.171 1.00 98.09 O +ATOM 11585 CB TYR G 21 78.963 -37.034 45.265 1.00161.64 C +ATOM 11586 CG TYR G 21 79.252 -36.144 46.460 1.00201.10 C +ATOM 11587 CD1 TYR G 21 78.547 -34.956 46.655 1.00203.24 C +ATOM 11588 CD2 TYR G 21 80.262 -36.466 47.366 1.00203.55 C +ATOM 11589 CE1 TYR G 21 78.826 -34.119 47.719 1.00190.09 C +ATOM 11590 CE2 TYR G 21 80.549 -35.628 48.438 1.00178.74 C +ATOM 11591 CZ TYR G 21 79.824 -34.454 48.610 1.00156.49 C +ATOM 11592 OH TYR G 21 80.050 -33.621 49.679 1.00 85.80 O +ATOM 11593 N LYS G 22 81.766 -37.416 44.051 1.00173.54 N +ATOM 11594 CA LYS G 22 83.221 -37.407 44.254 1.00165.73 C +ATOM 11595 C LYS G 22 83.927 -36.625 43.150 1.00166.97 C +ATOM 11596 O LYS G 22 84.849 -35.853 43.416 1.00158.92 O +ATOM 11597 CB LYS G 22 83.762 -38.842 44.275 1.00153.73 C +ATOM 11598 CG LYS G 22 83.776 -39.498 45.620 1.00144.22 C +ATOM 11599 CD LYS G 22 85.195 -39.804 46.051 1.00150.88 C +ATOM 11600 CE LYS G 22 86.374 -39.001 45.641 1.00147.25 C +ATOM 11601 NZ LYS G 22 86.976 -38.624 46.926 1.00124.91 N +ATOM 11602 N ASP G 23 83.440 -36.781 41.919 1.00159.14 N +ATOM 11603 CA ASP G 23 83.908 -35.979 40.786 1.00155.98 C +ATOM 11604 C ASP G 23 83.557 -34.496 40.959 1.00154.74 C +ATOM 11605 O ASP G 23 84.399 -33.619 40.748 1.00128.63 O +ATOM 11606 CB ASP G 23 83.284 -36.484 39.482 1.00164.24 C +ATOM 11607 CG ASP G 23 83.766 -37.850 39.100 1.00151.57 C +ATOM 11608 OD1 ASP G 23 84.972 -38.101 39.266 1.00116.18 O +ATOM 11609 OD2 ASP G 23 82.929 -38.670 38.653 1.00184.65 O +ATOM 11610 N LEU G 24 82.313 -34.239 41.362 1.00151.06 N +ATOM 11611 CA LEU G 24 81.778 -32.882 41.472 1.00157.42 C +ATOM 11612 C LEU G 24 82.501 -32.049 42.536 1.00175.19 C +ATOM 11613 O LEU G 24 82.711 -30.838 42.366 1.00200.62 O +ATOM 11614 CB LEU G 24 80.286 -32.952 41.810 1.00157.19 C +ATOM 11615 CG LEU G 24 79.525 -31.630 41.956 1.00166.95 C +ATOM 11616 CD1 LEU G 24 79.032 -31.127 40.604 1.00185.29 C +ATOM 11617 CD2 LEU G 24 78.357 -31.799 42.913 1.00162.51 C +ATOM 11618 N THR G 25 82.879 -32.702 43.634 1.00198.22 N +ATOM 11619 CA THR G 25 83.569 -32.025 44.737 1.00189.90 C +ATOM 11620 C THR G 25 85.033 -31.688 44.411 1.00170.19 C +ATOM 11621 O THR G 25 85.487 -30.563 44.645 1.00104.85 O +ATOM 11622 CB THR G 25 83.517 -32.872 46.026 1.00201.30 C +ATOM 11623 OG1 THR G 25 83.880 -34.235 45.728 1.00251.83 O +ATOM 11624 CG2 THR G 25 82.119 -32.828 46.620 1.00166.00 C +ATOM 11625 N HIS G 26 85.756 -32.670 43.866 1.00180.30 N +ATOM 11626 CA HIS G 26 87.186 -32.533 43.560 1.00159.46 C +ATOM 11627 C HIS G 26 87.401 -31.866 42.192 1.00142.80 C +ATOM 11628 O HIS G 26 88.317 -32.205 41.456 1.00163.39 O +ATOM 11629 CB HIS G 26 87.884 -33.912 43.629 1.00153.44 C +ATOM 11630 CG HIS G 26 87.880 -34.524 45.002 1.00172.90 C +ATOM 11631 ND1 HIS G 26 86.726 -34.968 45.611 1.00174.43 N +ATOM 11632 CD2 HIS G 26 88.873 -34.696 45.912 1.00167.51 C +ATOM 11633 CE1 HIS G 26 87.008 -35.387 46.833 1.00160.19 C +ATOM 11634 NE2 HIS G 26 88.306 -35.245 47.037 1.00144.71 N +ATOM 11635 N LEU G 27 86.543 -30.916 41.848 1.00133.53 N +ATOM 11636 CA LEU G 27 86.721 -30.146 40.623 1.00130.05 C +ATOM 11637 C LEU G 27 87.607 -28.937 40.909 1.00106.50 C +ATOM 11638 O LEU G 27 87.401 -28.235 41.898 1.00101.51 O +ATOM 11639 CB LEU G 27 85.362 -29.686 40.062 1.00159.91 C +ATOM 11640 CG LEU G 27 84.661 -30.675 39.123 1.00165.79 C +ATOM 11641 CD1 LEU G 27 83.215 -30.276 38.885 1.00159.70 C +ATOM 11642 CD2 LEU G 27 85.407 -30.780 37.797 1.00184.32 C +ATOM 11643 N PRO G 28 88.557 -28.652 40.011 1.00103.96 N +ATOM 11644 CA PRO G 28 89.456 -27.499 40.168 1.00109.24 C +ATOM 11645 C PRO G 28 88.706 -26.188 40.224 1.00 90.54 C +ATOM 11646 O PRO G 28 87.886 -25.936 39.360 1.00120.05 O +ATOM 11647 CB PRO G 28 90.325 -27.553 38.907 1.00123.97 C +ATOM 11648 CG PRO G 28 89.510 -28.318 37.909 1.00119.77 C +ATOM 11649 CD PRO G 28 88.743 -29.326 38.713 1.00118.89 C +ATOM 11650 N ALA G 29 88.969 -25.376 41.244 1.00 88.22 N +ATOM 11651 CA ALA G 29 88.138 -24.202 41.540 1.00 82.86 C +ATOM 11652 C ALA G 29 88.324 -23.060 40.491 1.00 92.02 C +ATOM 11653 O ALA G 29 89.392 -22.901 39.901 1.00 58.19 O +ATOM 11654 CB ALA G 29 88.394 -23.699 42.963 1.00 56.92 C +ATOM 11655 N PRO G 30 87.248 -22.298 40.214 1.00101.52 N +ATOM 11656 CA PRO G 30 87.280 -21.144 39.310 1.00 97.95 C +ATOM 11657 C PRO G 30 87.888 -19.922 39.989 1.00 89.57 C +ATOM 11658 O PRO G 30 88.220 -19.976 41.176 1.00 69.55 O +ATOM 11659 CB PRO G 30 85.813 -20.867 39.057 1.00118.39 C +ATOM 11660 CG PRO G 30 85.129 -21.323 40.307 1.00127.37 C +ATOM 11661 CD PRO G 30 85.924 -22.479 40.836 1.00106.86 C +ATOM 11662 N THR G 31 88.057 -18.841 39.231 1.00 97.13 N +ATOM 11663 CA THR G 31 88.707 -17.627 39.750 1.00113.03 C +ATOM 11664 C THR G 31 87.863 -16.970 40.839 1.00129.40 C +ATOM 11665 O THR G 31 88.381 -16.238 41.681 1.00173.81 O +ATOM 11666 CB THR G 31 89.055 -16.592 38.634 1.00107.89 C +ATOM 11667 OG1 THR G 31 87.907 -16.306 37.825 1.00 95.71 O +ATOM 11668 CG2 THR G 31 90.173 -17.111 37.737 1.00120.75 C +ATOM 11669 N GLY G 32 86.554 -17.170 40.762 1.00138.19 N +ATOM 11670 CA GLY G 32 85.643 -16.761 41.823 1.00147.62 C +ATOM 11671 C GLY G 32 84.390 -17.593 41.688 1.00158.85 C +ATOM 11672 O GLY G 32 84.073 -18.054 40.585 1.00189.84 O +ATOM 11673 N LYS G 33 83.671 -17.804 42.785 1.00133.93 N +ATOM 11674 CA LYS G 33 82.402 -18.509 42.679 1.00115.31 C +ATOM 11675 C LYS G 33 81.373 -17.685 41.880 1.00151.39 C +ATOM 11676 O LYS G 33 81.416 -16.448 41.899 1.00152.50 O +ATOM 11677 CB LYS G 33 81.858 -18.874 44.051 1.00 94.68 C +ATOM 11678 CG LYS G 33 82.316 -20.218 44.565 1.00 99.32 C +ATOM 11679 CD LYS G 33 81.881 -20.451 46.004 1.00 96.53 C +ATOM 11680 CE LYS G 33 82.818 -21.410 46.704 1.00 93.74 C +ATOM 11681 NZ LYS G 33 82.516 -21.512 48.139 1.00101.27 N +ATOM 11682 N ILE G 34 80.449 -18.370 41.199 1.00155.46 N +ATOM 11683 CA ILE G 34 79.442 -17.702 40.374 1.00127.29 C +ATOM 11684 C ILE G 34 78.071 -17.764 41.075 1.00110.28 C +ATOM 11685 O ILE G 34 77.798 -18.699 41.836 1.00 64.09 O +ATOM 11686 CB ILE G 34 79.414 -18.299 38.953 1.00119.29 C +ATOM 11687 CG1 ILE G 34 80.733 -17.998 38.239 1.00126.67 C +ATOM 11688 CG2 ILE G 34 78.296 -17.712 38.112 1.00146.33 C +ATOM 11689 CD1 ILE G 34 81.495 -19.249 37.866 1.00171.06 C +ATOM 11690 N PHE G 35 77.319 -16.655 40.972 1.00113.16 N +ATOM 11691 CA PHE G 35 76.009 -16.478 41.623 1.00 81.95 C +ATOM 11692 C PHE G 35 74.893 -17.074 40.784 1.00 67.17 C +ATOM 11693 O PHE G 35 74.805 -16.750 39.615 1.00 56.55 O +ATOM 11694 CB PHE G 35 75.707 -15.001 41.745 1.00 69.64 C +ATOM 11695 CG PHE G 35 76.254 -14.364 42.983 1.00 80.18 C +ATOM 11696 CD1 PHE G 35 76.121 -14.979 44.244 1.00 67.46 C +ATOM 11697 CD2 PHE G 35 76.792 -13.088 42.917 1.00 83.04 C +ATOM 11698 CE1 PHE G 35 76.592 -14.360 45.384 1.00 61.31 C +ATOM 11699 CE2 PHE G 35 77.225 -12.449 44.066 1.00 80.88 C +ATOM 11700 CZ PHE G 35 77.147 -13.094 45.297 1.00 70.72 C +ATOM 11701 N VAL G 36 74.121 -18.006 41.350 1.00 52.21 N +ATOM 11702 CA VAL G 36 73.195 -18.784 40.550 1.00 47.03 C +ATOM 11703 C VAL G 36 71.843 -18.915 41.192 1.00 53.62 C +ATOM 11704 O VAL G 36 71.705 -18.802 42.419 1.00 65.15 O +ATOM 11705 CB VAL G 36 73.694 -20.203 40.304 1.00 48.69 C +ATOM 11706 CG1 VAL G 36 73.550 -21.081 41.545 1.00 37.37 C +ATOM 11707 CG2 VAL G 36 72.930 -20.786 39.134 1.00 63.66 C +ATOM 11708 N SER G 37 70.814 -18.984 40.357 1.00 54.32 N +ATOM 11709 CA SER G 37 69.434 -18.995 40.858 1.00 64.78 C +ATOM 11710 C SER G 37 68.785 -20.244 40.342 1.00 60.41 C +ATOM 11711 O SER G 37 68.840 -20.494 39.146 1.00 63.17 O +ATOM 11712 CB SER G 37 68.642 -17.769 40.351 1.00 64.82 C +ATOM 11713 OG SER G 37 68.983 -16.569 41.020 1.00 50.45 O +ATOM 11714 N VAL G 38 68.127 -20.994 41.213 1.00 55.15 N +ATOM 11715 CA VAL G 38 67.248 -22.041 40.738 1.00 64.70 C +ATOM 11716 C VAL G 38 65.836 -21.808 41.241 1.00 85.23 C +ATOM 11717 O VAL G 38 65.605 -21.793 42.459 1.00 70.43 O +ATOM 11718 CB VAL G 38 67.682 -23.418 41.223 1.00 66.38 C +ATOM 11719 CG1 VAL G 38 66.709 -24.460 40.723 1.00 89.60 C +ATOM 11720 CG2 VAL G 38 69.075 -23.754 40.726 1.00 82.48 C +ATOM 11721 N TYR G 39 64.893 -21.623 40.298 1.00109.32 N +ATOM 11722 CA TYR G 39 63.483 -21.340 40.617 1.00101.83 C +ATOM 11723 C TYR G 39 62.687 -22.653 40.734 1.00 86.25 C +ATOM 11724 O TYR G 39 62.080 -22.932 41.772 1.00 78.49 O +ATOM 11725 CB TYR G 39 62.862 -20.384 39.566 1.00103.22 C +ATOM 11726 CG TYR G 39 63.100 -18.881 39.837 1.00113.09 C +ATOM 11727 CD1 TYR G 39 64.308 -18.290 39.553 1.00 86.40 C +ATOM 11728 CD2 TYR G 39 62.103 -18.080 40.428 1.00116.03 C +ATOM 11729 CE1 TYR G 39 64.533 -16.963 39.879 1.00 82.91 C +ATOM 11730 CE2 TYR G 39 62.325 -16.756 40.759 1.00 78.40 C +ATOM 11731 CZ TYR G 39 63.542 -16.201 40.479 1.00 74.20 C +ATOM 11732 OH TYR G 39 63.768 -14.876 40.775 1.00 71.14 O +ATOM 11733 N ASN G 40 62.772 -23.502 39.718 1.00 88.84 N +ATOM 11734 CA ASN G 40 62.074 -24.788 39.760 1.00 98.38 C +ATOM 11735 C ASN G 40 62.497 -25.780 38.671 1.00100.12 C +ATOM 11736 O ASN G 40 62.604 -25.425 37.492 1.00117.90 O +ATOM 11737 CB ASN G 40 60.579 -24.538 39.626 1.00108.80 C +ATOM 11738 CG ASN G 40 59.750 -25.713 40.083 1.00128.53 C +ATOM 11739 OD1 ASN G 40 59.045 -26.333 39.289 1.00147.00 O +ATOM 11740 ND2 ASN G 40 59.851 -26.045 41.364 1.00145.07 N +ATOM 11741 N ILE G 41 62.723 -27.029 39.065 1.00 94.87 N +ATOM 11742 CA ILE G 41 62.900 -28.123 38.106 1.00111.38 C +ATOM 11743 C ILE G 41 61.765 -29.140 38.272 1.00113.99 C +ATOM 11744 O ILE G 41 61.632 -29.750 39.337 1.00142.77 O +ATOM 11745 CB ILE G 41 64.259 -28.836 38.291 1.00106.27 C +ATOM 11746 CG1 ILE G 41 65.385 -28.048 37.619 1.00113.07 C +ATOM 11747 CG2 ILE G 41 64.231 -30.196 37.623 1.00 94.53 C +ATOM 11748 CD1 ILE G 41 65.769 -26.757 38.301 1.00117.33 C +ATOM 11749 N GLN G 42 60.943 -29.309 37.236 1.00106.21 N +ATOM 11750 CA GLN G 42 59.674 -30.051 37.372 1.00115.84 C +ATOM 11751 C GLN G 42 59.834 -31.528 37.090 1.00115.56 C +ATOM 11752 O GLN G 42 60.749 -31.938 36.379 1.00114.68 O +ATOM 11753 CB GLN G 42 58.595 -29.506 36.433 1.00108.19 C +ATOM 11754 CG GLN G 42 58.154 -28.097 36.748 1.00107.60 C +ATOM 11755 CD GLN G 42 58.436 -27.144 35.596 1.00121.21 C +ATOM 11756 OE1 GLN G 42 57.615 -26.990 34.688 1.00144.07 O +ATOM 11757 NE2 GLN G 42 59.610 -26.509 35.614 1.00126.89 N +ATOM 11758 N ASP G 43 58.907 -32.315 37.635 1.00110.93 N +ATOM 11759 CA ASP G 43 58.761 -33.725 37.291 1.00111.93 C +ATOM 11760 C ASP G 43 57.987 -33.863 35.982 1.00 88.95 C +ATOM 11761 O ASP G 43 56.880 -34.398 35.971 1.00 64.42 O +ATOM 11762 CB ASP G 43 58.025 -34.476 38.411 1.00120.25 C +ATOM 11763 CG ASP G 43 58.043 -36.001 38.220 1.00145.55 C +ATOM 11764 OD1 ASP G 43 59.134 -36.559 37.980 1.00132.72 O +ATOM 11765 OD2 ASP G 43 56.973 -36.654 38.317 1.00144.43 O +ATOM 11766 N GLU G 44 58.588 -33.395 34.885 1.00 91.33 N +ATOM 11767 CA GLU G 44 57.944 -33.407 33.570 1.00 97.15 C +ATOM 11768 C GLU G 44 57.809 -34.842 33.012 1.00 92.98 C +ATOM 11769 O GLU G 44 57.481 -35.030 31.826 1.00 90.64 O +ATOM 11770 CB GLU G 44 58.707 -32.495 32.574 1.00105.41 C +ATOM 11771 CG GLU G 44 58.290 -31.016 32.576 1.00109.75 C +ATOM 11772 CD GLU G 44 59.085 -30.124 31.595 1.00143.74 C +ATOM 11773 OE1 GLU G 44 59.336 -30.505 30.423 1.00160.41 O +ATOM 11774 OE2 GLU G 44 59.481 -29.002 31.988 1.00170.16 O +ATOM 11775 N THR G 45 57.990 -35.840 33.883 1.00 92.25 N +ATOM 11776 CA THR G 45 58.062 -37.247 33.468 1.00118.83 C +ATOM 11777 C THR G 45 56.710 -37.861 33.085 1.00103.40 C +ATOM 11778 O THR G 45 56.616 -38.609 32.122 1.00 95.12 O +ATOM 11779 CB THR G 45 58.779 -38.131 34.516 1.00126.93 C +ATOM 11780 OG1 THR G 45 59.104 -39.395 33.944 1.00180.27 O +ATOM 11781 CG2 THR G 45 57.922 -38.382 35.750 1.00134.21 C +ATOM 11782 N GLY G 46 55.672 -37.569 33.850 1.00102.66 N +ATOM 11783 CA GLY G 46 54.305 -37.989 33.498 1.00105.77 C +ATOM 11784 C GLY G 46 53.955 -39.377 34.017 1.00 95.24 C +ATOM 11785 O GLY G 46 52.984 -40.031 33.597 1.00133.30 O +ATOM 11786 N GLN G 47 54.655 -39.801 35.034 1.00 83.76 N +ATOM 11787 CA GLN G 47 54.601 -41.172 35.333 1.00 90.26 C +ATOM 11788 C GLN G 47 54.353 -41.442 36.804 1.00107.14 C +ATOM 11789 O GLN G 47 54.894 -40.741 37.703 1.00132.87 O +ATOM 11790 CB GLN G 47 55.882 -41.767 34.861 1.00104.99 C +ATOM 11791 CG GLN G 47 56.013 -41.777 33.346 1.00 96.03 C +ATOM 11792 CD GLN G 47 54.822 -42.369 32.649 1.00111.04 C +ATOM 11793 OE1 GLN G 47 54.574 -43.564 32.729 1.00140.36 O +ATOM 11794 NE2 GLN G 47 54.050 -41.537 31.995 1.00163.70 N +ATOM 11795 N PHE G 48 53.518 -42.455 37.039 1.00 68.63 N +ATOM 11796 CA PHE G 48 53.201 -42.885 38.393 1.00 86.32 C +ATOM 11797 C PHE G 48 53.531 -44.352 38.590 1.00 88.79 C +ATOM 11798 O PHE G 48 53.692 -45.101 37.620 1.00 85.59 O +ATOM 11799 CB PHE G 48 51.713 -42.629 38.689 1.00107.44 C +ATOM 11800 CG PHE G 48 51.362 -41.190 38.738 1.00 89.39 C +ATOM 11801 CD1 PHE G 48 51.263 -40.475 37.559 1.00 70.41 C +ATOM 11802 CD2 PHE G 48 51.232 -40.539 39.958 1.00 73.38 C +ATOM 11803 CE1 PHE G 48 51.074 -39.125 37.584 1.00 75.01 C +ATOM 11804 CE2 PHE G 48 51.026 -39.192 39.991 1.00 84.34 C +ATOM 11805 CZ PHE G 48 50.921 -38.485 38.798 1.00 97.01 C +ATOM 11806 N LYS G 49 53.496 -44.776 39.855 1.00107.23 N +ATOM 11807 CA LYS G 49 53.764 -46.159 40.210 1.00111.98 C +ATOM 11808 C LYS G 49 52.571 -47.048 39.896 1.00119.65 C +ATOM 11809 O LYS G 49 51.411 -46.615 40.003 1.00121.61 O +ATOM 11810 CB LYS G 49 54.154 -46.276 41.688 1.00 99.20 C +ATOM 11811 CG LYS G 49 55.456 -45.548 41.966 1.00115.11 C +ATOM 11812 CD LYS G 49 56.068 -45.770 43.334 1.00140.89 C +ATOM 11813 CE LYS G 49 57.451 -45.096 43.316 1.00177.55 C +ATOM 11814 NZ LYS G 49 58.249 -45.231 44.565 1.00214.62 N +ATOM 11815 N PRO G 50 52.857 -48.283 39.458 1.00118.56 N +ATOM 11816 CA PRO G 50 51.825 -49.267 39.161 1.00123.79 C +ATOM 11817 C PRO G 50 51.259 -49.956 40.412 1.00106.40 C +ATOM 11818 O PRO G 50 51.782 -49.798 41.526 1.00 61.13 O +ATOM 11819 CB PRO G 50 52.556 -50.292 38.295 1.00130.10 C +ATOM 11820 CG PRO G 50 53.967 -50.218 38.766 1.00144.61 C +ATOM 11821 CD PRO G 50 54.206 -48.793 39.165 1.00120.63 C +ATOM 11822 N TYR G 51 50.162 -50.685 40.212 1.00 87.70 N +ATOM 11823 CA TYR G 51 49.588 -51.472 41.278 1.00 74.37 C +ATOM 11824 C TYR G 51 50.683 -52.306 41.881 1.00 61.47 C +ATOM 11825 O TYR G 51 51.484 -52.897 41.140 1.00 74.40 O +ATOM 11826 CB TYR G 51 48.464 -52.373 40.738 1.00 78.40 C +ATOM 11827 CG TYR G 51 47.641 -52.970 41.854 1.00 76.22 C +ATOM 11828 CD1 TYR G 51 46.572 -52.262 42.386 1.00 97.15 C +ATOM 11829 CD2 TYR G 51 47.935 -54.208 42.395 1.00 75.78 C +ATOM 11830 CE1 TYR G 51 45.816 -52.758 43.431 1.00 98.25 C +ATOM 11831 CE2 TYR G 51 47.163 -54.736 43.435 1.00 92.76 C +ATOM 11832 CZ TYR G 51 46.128 -53.975 43.972 1.00104.60 C +ATOM 11833 OH TYR G 51 45.334 -54.424 45.006 1.00109.78 O +ATOM 11834 N PRO G 52 50.713 -52.409 43.212 1.00 61.75 N +ATOM 11835 CA PRO G 52 49.740 -51.951 44.211 1.00 70.29 C +ATOM 11836 C PRO G 52 49.975 -50.580 44.798 1.00 89.83 C +ATOM 11837 O PRO G 52 49.447 -50.292 45.889 1.00 74.91 O +ATOM 11838 CB PRO G 52 49.866 -53.000 45.323 1.00 70.95 C +ATOM 11839 CG PRO G 52 51.310 -53.386 45.274 1.00 89.74 C +ATOM 11840 CD PRO G 52 51.729 -53.294 43.816 1.00 76.25 C +ATOM 11841 N ALA G 53 50.795 -49.746 44.149 1.00102.75 N +ATOM 11842 CA ALA G 53 51.057 -48.406 44.696 1.00115.32 C +ATOM 11843 C ALA G 53 49.745 -47.627 44.721 1.00 91.16 C +ATOM 11844 O ALA G 53 48.823 -47.935 43.952 1.00 88.57 O +ATOM 11845 CB ALA G 53 52.142 -47.663 43.894 1.00113.80 C +ATOM 11846 N SER G 54 49.675 -46.598 45.561 1.00 65.91 N +ATOM 11847 CA SER G 54 48.610 -45.633 45.392 1.00 49.57 C +ATOM 11848 C SER G 54 48.646 -45.040 43.992 1.00 56.11 C +ATOM 11849 O SER G 54 49.717 -44.827 43.343 1.00 75.42 O +ATOM 11850 CB SER G 54 48.720 -44.500 46.369 1.00 58.25 C +ATOM 11851 OG SER G 54 48.006 -43.333 45.932 1.00 41.23 O +ATOM 11852 N ASN G 55 47.451 -44.812 43.477 1.00 57.94 N +ATOM 11853 CA ASN G 55 47.291 -44.226 42.161 1.00 54.58 C +ATOM 11854 C ASN G 55 48.185 -42.988 42.006 1.00 52.15 C +ATOM 11855 O ASN G 55 48.590 -42.602 40.895 1.00 32.48 O +ATOM 11856 CB ASN G 55 45.814 -43.875 41.979 1.00 45.38 C +ATOM 11857 CG ASN G 55 45.500 -43.531 40.560 1.00 76.14 C +ATOM 11858 OD1 ASN G 55 46.184 -43.948 39.606 1.00116.54 O +ATOM 11859 ND2 ASN G 55 44.428 -42.826 40.389 1.00100.63 N +ATOM 11860 N PHE G 56 48.391 -42.316 43.148 1.00 59.78 N +ATOM 11861 CA PHE G 56 48.940 -40.957 43.197 1.00 66.47 C +ATOM 11862 C PHE G 56 50.413 -40.930 43.508 1.00 65.53 C +ATOM 11863 O PHE G 56 51.013 -39.867 43.578 1.00 71.50 O +ATOM 11864 CB PHE G 56 48.261 -40.123 44.285 1.00 59.61 C +ATOM 11865 CG PHE G 56 46.786 -39.966 44.099 1.00 51.70 C +ATOM 11866 CD1 PHE G 56 46.249 -39.363 42.964 1.00 43.84 C +ATOM 11867 CD2 PHE G 56 45.949 -40.428 45.046 1.00 62.51 C +ATOM 11868 CE1 PHE G 56 44.898 -39.265 42.789 1.00 47.34 C +ATOM 11869 CE2 PHE G 56 44.577 -40.277 44.905 1.00 74.34 C +ATOM 11870 CZ PHE G 56 44.051 -39.719 43.764 1.00 56.30 C +ATOM 11871 N SER G 57 50.988 -42.087 43.749 1.00 60.16 N +ATOM 11872 CA SER G 57 52.422 -42.140 43.967 1.00 56.23 C +ATOM 11873 C SER G 57 53.202 -41.906 42.635 1.00 59.97 C +ATOM 11874 O SER G 57 53.129 -42.675 41.674 1.00 52.44 O +ATOM 11875 CB SER G 57 52.787 -43.476 44.600 1.00 63.09 C +ATOM 11876 OG SER G 57 52.312 -43.516 45.942 1.00 49.96 O +ATOM 11877 N THR G 58 53.932 -40.817 42.581 1.00 71.66 N +ATOM 11878 CA THR G 58 54.702 -40.495 41.398 1.00 90.46 C +ATOM 11879 C THR G 58 55.859 -41.430 41.240 1.00 89.25 C +ATOM 11880 O THR G 58 56.432 -41.904 42.218 1.00 92.20 O +ATOM 11881 CB THR G 58 55.272 -39.076 41.504 1.00119.44 C +ATOM 11882 OG1 THR G 58 56.125 -38.965 42.654 1.00 79.74 O +ATOM 11883 CG2 THR G 58 54.147 -38.099 41.673 1.00155.38 C +ATOM 11884 N ALA G 59 56.324 -41.580 40.023 1.00 88.10 N +ATOM 11885 CA ALA G 59 57.409 -42.506 39.839 1.00110.55 C +ATOM 11886 C ALA G 59 58.735 -41.887 40.232 1.00113.07 C +ATOM 11887 O ALA G 59 59.699 -42.605 40.528 1.00152.82 O +ATOM 11888 CB ALA G 59 57.464 -42.966 38.413 1.00115.71 C +ATOM 11889 N VAL G 60 58.771 -40.558 40.287 1.00103.43 N +ATOM 11890 CA VAL G 60 60.011 -39.811 40.537 1.00 95.72 C +ATOM 11891 C VAL G 60 59.772 -38.765 41.611 1.00100.48 C +ATOM 11892 O VAL G 60 58.701 -38.160 41.657 1.00169.88 O +ATOM 11893 CB VAL G 60 60.444 -39.096 39.254 1.00 80.18 C +ATOM 11894 CG1 VAL G 60 61.702 -38.302 39.464 1.00 65.28 C +ATOM 11895 CG2 VAL G 60 60.624 -40.128 38.143 1.00124.33 C +ATOM 11896 N PRO G 61 60.726 -38.606 42.537 1.00105.12 N +ATOM 11897 CA PRO G 61 60.501 -37.625 43.583 1.00127.61 C +ATOM 11898 C PRO G 61 60.393 -36.207 43.009 1.00144.14 C +ATOM 11899 O PRO G 61 61.117 -35.861 42.061 1.00157.41 O +ATOM 11900 CB PRO G 61 61.735 -37.782 44.485 1.00116.80 C +ATOM 11901 CG PRO G 61 62.759 -38.436 43.624 1.00 92.36 C +ATOM 11902 CD PRO G 61 61.985 -39.335 42.731 1.00 92.90 C +ATOM 11903 N GLN G 62 59.560 -35.383 43.644 1.00125.18 N +ATOM 11904 CA GLN G 62 59.309 -34.025 43.176 1.00114.63 C +ATOM 11905 C GLN G 62 60.328 -33.018 43.690 1.00110.32 C +ATOM 11906 O GLN G 62 59.980 -31.906 44.032 1.00 90.83 O +ATOM 11907 CB GLN G 62 57.902 -33.597 43.617 1.00132.36 C +ATOM 11908 CG GLN G 62 56.807 -34.593 43.284 1.00122.34 C +ATOM 11909 CD GLN G 62 56.753 -34.876 41.798 1.00127.72 C +ATOM 11910 OE1 GLN G 62 56.226 -34.085 41.021 1.00160.10 O +ATOM 11911 NE2 GLN G 62 57.335 -35.979 41.389 1.00149.40 N +ATOM 11912 N SER G 63 61.568 -33.452 43.850 1.00130.71 N +ATOM 11913 CA SER G 63 62.509 -32.781 44.749 1.00128.01 C +ATOM 11914 C SER G 63 63.749 -32.323 43.995 1.00103.98 C +ATOM 11915 O SER G 63 64.738 -31.915 44.597 1.00115.64 O +ATOM 11916 CB SER G 63 62.881 -33.710 45.940 1.00138.89 C +ATOM 11917 OG SER G 63 63.526 -34.922 45.549 1.00120.20 O +ATOM 11918 N ALA G 64 63.699 -32.462 42.678 1.00 87.46 N +ATOM 11919 CA ALA G 64 64.854 -32.236 41.816 1.00 76.77 C +ATOM 11920 C ALA G 64 65.472 -30.847 41.986 1.00 76.79 C +ATOM 11921 O ALA G 64 66.700 -30.701 42.016 1.00103.72 O +ATOM 11922 CB ALA G 64 64.440 -32.428 40.382 1.00 79.04 C +ATOM 11923 N THR G 65 64.618 -29.863 42.225 1.00 89.49 N +ATOM 11924 CA THR G 65 65.035 -28.492 42.442 1.00100.56 C +ATOM 11925 C THR G 65 66.054 -28.355 43.559 1.00102.11 C +ATOM 11926 O THR G 65 67.126 -27.752 43.372 1.00125.23 O +ATOM 11927 CB THR G 65 63.836 -27.640 42.854 1.00116.60 C +ATOM 11928 OG1 THR G 65 62.701 -28.060 42.094 1.00163.64 O +ATOM 11929 CG2 THR G 65 64.117 -26.154 42.620 1.00120.92 C +ATOM 11930 N ALA G 66 65.738 -28.935 44.709 1.00 80.55 N +ATOM 11931 CA ALA G 66 66.626 -28.838 45.846 1.00 90.98 C +ATOM 11932 C ALA G 66 67.938 -29.623 45.642 1.00 91.90 C +ATOM 11933 O ALA G 66 69.022 -29.203 46.085 1.00 82.18 O +ATOM 11934 CB ALA G 66 65.903 -29.313 47.090 1.00108.14 C +ATOM 11935 N MET G 67 67.838 -30.756 44.948 1.00 96.45 N +ATOM 11936 CA MET G 67 69.024 -31.552 44.593 1.00109.52 C +ATOM 11937 C MET G 67 69.991 -30.756 43.695 1.00 97.71 C +ATOM 11938 O MET G 67 71.206 -30.795 43.890 1.00 70.06 O +ATOM 11939 CB MET G 67 68.622 -32.856 43.875 1.00113.32 C +ATOM 11940 CG MET G 67 67.915 -33.888 44.746 1.00131.36 C +ATOM 11941 SD MET G 67 67.190 -35.208 43.741 1.00136.93 S +ATOM 11942 CE MET G 67 66.604 -36.332 45.016 1.00130.14 C +ATOM 11943 N LEU G 68 69.434 -30.060 42.708 1.00101.29 N +ATOM 11944 CA LEU G 68 70.240 -29.262 41.811 1.00 87.98 C +ATOM 11945 C LEU G 68 70.922 -28.148 42.565 1.00106.20 C +ATOM 11946 O LEU G 68 72.098 -27.905 42.360 1.00 93.21 O +ATOM 11947 CB LEU G 68 69.394 -28.654 40.705 1.00112.63 C +ATOM 11948 CG LEU G 68 70.166 -27.613 39.869 1.00139.72 C +ATOM 11949 CD1 LEU G 68 71.292 -28.281 39.098 1.00148.53 C +ATOM 11950 CD2 LEU G 68 69.257 -26.845 38.915 1.00136.40 C +ATOM 11951 N VAL G 69 70.181 -27.448 43.432 1.00150.68 N +ATOM 11952 CA VAL G 69 70.770 -26.356 44.225 1.00141.37 C +ATOM 11953 C VAL G 69 71.923 -26.899 45.071 1.00140.03 C +ATOM 11954 O VAL G 69 72.999 -26.300 45.153 1.00125.30 O +ATOM 11955 CB VAL G 69 69.748 -25.668 45.156 1.00121.78 C +ATOM 11956 CG1 VAL G 69 70.467 -24.676 46.060 1.00101.40 C +ATOM 11957 CG2 VAL G 69 68.654 -24.954 44.362 1.00102.71 C +ATOM 11958 N THR G 70 71.693 -28.057 45.683 1.00133.36 N +ATOM 11959 CA THR G 70 72.704 -28.694 46.516 1.00125.90 C +ATOM 11960 C THR G 70 73.934 -29.082 45.700 1.00102.90 C +ATOM 11961 O THR G 70 75.081 -28.831 46.114 1.00104.79 O +ATOM 11962 CB THR G 70 72.123 -29.929 47.224 1.00112.56 C +ATOM 11963 OG1 THR G 70 70.966 -29.524 47.970 1.00 80.68 O +ATOM 11964 CG2 THR G 70 73.170 -30.554 48.174 1.00127.67 C +ATOM 11965 N ALA G 71 73.698 -29.670 44.536 1.00 86.77 N +ATOM 11966 CA ALA G 71 74.807 -30.027 43.653 1.00107.61 C +ATOM 11967 C ALA G 71 75.601 -28.789 43.219 1.00 93.81 C +ATOM 11968 O ALA G 71 76.839 -28.804 43.165 1.00 76.85 O +ATOM 11969 CB ALA G 71 74.293 -30.791 42.436 1.00104.97 C +ATOM 11970 N LEU G 72 74.878 -27.725 42.902 1.00103.05 N +ATOM 11971 CA LEU G 72 75.512 -26.468 42.496 1.00116.50 C +ATOM 11972 C LEU G 72 76.382 -25.921 43.610 1.00114.21 C +ATOM 11973 O LEU G 72 77.329 -25.185 43.354 1.00118.68 O +ATOM 11974 CB LEU G 72 74.459 -25.414 42.095 1.00104.77 C +ATOM 11975 CG LEU G 72 73.698 -25.717 40.811 1.00 81.86 C +ATOM 11976 CD1 LEU G 72 72.468 -24.883 40.767 1.00 70.62 C +ATOM 11977 CD2 LEU G 72 74.545 -25.472 39.581 1.00101.08 C +ATOM 11978 N LYS G 73 76.038 -26.252 44.852 1.00 93.76 N +ATOM 11979 CA LYS G 73 76.817 -25.761 45.977 1.00104.68 C +ATOM 11980 C LYS G 73 78.038 -26.643 46.186 1.00103.94 C +ATOM 11981 O LYS G 73 79.117 -26.141 46.452 1.00105.45 O +ATOM 11982 CB LYS G 73 75.979 -25.676 47.271 1.00121.18 C +ATOM 11983 CG LYS G 73 76.675 -24.887 48.396 1.00113.99 C +ATOM 11984 CD LYS G 73 75.841 -24.805 49.680 1.00104.04 C +ATOM 11985 CE LYS G 73 76.724 -24.642 50.915 1.00 82.27 C +ATOM 11986 NZ LYS G 73 76.590 -23.319 51.582 1.00 56.87 N +ATOM 11987 N ASP G 74 77.832 -27.958 46.180 1.00104.49 N +ATOM 11988 CA ASP G 74 78.892 -28.905 46.532 1.00 96.48 C +ATOM 11989 C ASP G 74 80.047 -28.761 45.564 1.00 91.78 C +ATOM 11990 O ASP G 74 81.193 -29.059 45.919 1.00135.75 O +ATOM 11991 CB ASP G 74 78.362 -30.347 46.526 1.00100.34 C +ATOM 11992 CG ASP G 74 77.396 -30.647 47.686 1.00 85.44 C +ATOM 11993 OD1 ASP G 74 77.498 -30.020 48.775 1.00 52.46 O +ATOM 11994 OD2 ASP G 74 76.522 -31.528 47.482 1.00 68.76 O +ATOM 11995 N SER G 75 79.744 -28.318 44.345 1.00 79.46 N +ATOM 11996 CA SER G 75 80.762 -28.204 43.293 1.00122.13 C +ATOM 11997 C SER G 75 81.844 -27.180 43.626 1.00116.26 C +ATOM 11998 O SER G 75 82.957 -27.235 43.093 1.00 90.59 O +ATOM 11999 CB SER G 75 80.114 -27.837 41.957 1.00144.18 C +ATOM 12000 OG SER G 75 79.938 -26.434 41.836 1.00171.99 O +ATOM 12001 N ARG G 76 81.485 -26.236 44.486 1.00112.08 N +ATOM 12002 CA ARG G 76 82.353 -25.124 44.840 1.00133.89 C +ATOM 12003 C ARG G 76 82.723 -24.313 43.611 1.00121.51 C +ATOM 12004 O ARG G 76 83.795 -23.724 43.543 1.00110.13 O +ATOM 12005 CB ARG G 76 83.610 -25.610 45.540 1.00144.44 C +ATOM 12006 CG ARG G 76 83.357 -26.378 46.828 1.00133.45 C +ATOM 12007 CD ARG G 76 84.678 -26.788 47.449 1.00151.34 C +ATOM 12008 NE ARG G 76 85.342 -27.813 46.637 1.00149.15 N +ATOM 12009 CZ ARG G 76 86.278 -27.576 45.717 1.00165.61 C +ATOM 12010 NH1 ARG G 76 86.688 -26.334 45.438 1.00157.01 N +ATOM 12011 NH2 ARG G 76 86.805 -28.598 45.061 1.00166.35 N +ATOM 12012 N TRP G 77 81.745 -24.160 42.728 1.00139.09 N +ATOM 12013 CA TRP G 77 81.791 -23.191 41.638 1.00153.85 C +ATOM 12014 C TRP G 77 80.716 -22.072 41.775 1.00161.43 C +ATOM 12015 O TRP G 77 80.945 -20.922 41.379 1.00 90.93 O +ATOM 12016 CB TRP G 77 81.582 -23.941 40.329 1.00142.37 C +ATOM 12017 CG TRP G 77 82.819 -24.418 39.707 1.00114.00 C +ATOM 12018 CD1 TRP G 77 83.569 -25.481 40.088 1.00 92.83 C +ATOM 12019 CD2 TRP G 77 83.448 -23.861 38.546 1.00 96.17 C +ATOM 12020 NE1 TRP G 77 84.638 -25.608 39.251 1.00110.39 N +ATOM 12021 CE2 TRP G 77 84.586 -24.618 38.299 1.00 91.87 C +ATOM 12022 CE3 TRP G 77 83.161 -22.782 37.703 1.00 90.37 C +ATOM 12023 CZ2 TRP G 77 85.446 -24.340 37.238 1.00 93.95 C +ATOM 12024 CZ3 TRP G 77 84.026 -22.499 36.667 1.00 89.03 C +ATOM 12025 CH2 TRP G 77 85.150 -23.277 36.440 1.00 87.02 C +ATOM 12026 N PHE G 78 79.579 -22.417 42.382 1.00178.03 N +ATOM 12027 CA PHE G 78 78.405 -21.545 42.443 1.00146.95 C +ATOM 12028 C PHE G 78 77.949 -21.275 43.874 1.00132.13 C +ATOM 12029 O PHE G 78 77.994 -22.171 44.713 1.00 98.31 O +ATOM 12030 CB PHE G 78 77.240 -22.200 41.716 1.00138.86 C +ATOM 12031 CG PHE G 78 77.541 -22.577 40.297 1.00141.37 C +ATOM 12032 CD1 PHE G 78 77.638 -21.599 39.298 1.00111.04 C +ATOM 12033 CD2 PHE G 78 77.701 -23.916 39.954 1.00114.13 C +ATOM 12034 CE1 PHE G 78 77.847 -21.956 37.989 1.00 83.54 C +ATOM 12035 CE2 PHE G 78 77.920 -24.280 38.645 1.00 94.74 C +ATOM 12036 CZ PHE G 78 77.991 -23.296 37.662 1.00 94.60 C +ATOM 12037 N ILE G 79 77.490 -20.044 44.113 1.00132.27 N +ATOM 12038 CA ILE G 79 76.699 -19.683 45.296 1.00108.04 C +ATOM 12039 C ILE G 79 75.236 -19.654 44.901 1.00112.07 C +ATOM 12040 O ILE G 79 74.901 -19.035 43.884 1.00107.36 O +ATOM 12041 CB ILE G 79 77.030 -18.281 45.771 1.00 94.80 C +ATOM 12042 CG1 ILE G 79 78.541 -18.086 45.890 1.00114.19 C +ATOM 12043 CG2 ILE G 79 76.367 -18.015 47.112 1.00110.35 C +ATOM 12044 CD1 ILE G 79 78.988 -16.631 45.820 1.00112.50 C +ATOM 12045 N PRO G 80 74.413 -20.478 45.568 1.00132.17 N +ATOM 12046 CA PRO G 80 73.038 -20.491 45.117 1.00131.30 C +ATOM 12047 C PRO G 80 72.266 -19.500 45.902 1.00114.83 C +ATOM 12048 O PRO G 80 72.458 -19.384 47.113 1.00135.66 O +ATOM 12049 CB PRO G 80 72.560 -21.910 45.435 1.00116.60 C +ATOM 12050 CG PRO G 80 73.794 -22.723 45.441 1.00162.06 C +ATOM 12051 CD PRO G 80 74.801 -21.800 46.093 1.00163.15 C +ATOM 12052 N LEU G 81 71.472 -18.724 45.198 1.00 91.51 N +ATOM 12053 CA LEU G 81 70.610 -17.786 45.828 1.00104.09 C +ATOM 12054 C LEU G 81 69.263 -18.420 45.977 1.00 96.37 C +ATOM 12055 O LEU G 81 68.808 -19.150 45.090 1.00 95.65 O +ATOM 12056 CB LEU G 81 70.545 -16.499 45.015 1.00130.15 C +ATOM 12057 CG LEU G 81 71.941 -15.898 44.784 1.00145.97 C +ATOM 12058 CD1 LEU G 81 71.810 -14.704 43.868 1.00103.02 C +ATOM 12059 CD2 LEU G 81 72.579 -15.490 46.102 1.00157.93 C +ATOM 12060 N GLU G 82 68.660 -18.178 47.142 1.00139.22 N +ATOM 12061 CA GLU G 82 67.376 -18.778 47.497 1.00174.86 C +ATOM 12062 C GLU G 82 66.195 -18.095 46.786 1.00143.64 C +ATOM 12063 O GLU G 82 65.803 -16.970 47.116 1.00 91.08 O +ATOM 12064 CB GLU G 82 67.153 -18.789 49.023 1.00188.75 C +ATOM 12065 CG GLU G 82 65.833 -19.427 49.481 1.00189.51 C +ATOM 12066 CD GLU G 82 65.762 -20.957 49.304 1.00150.25 C +ATOM 12067 OE1 GLU G 82 66.058 -21.501 48.210 1.00113.10 O +ATOM 12068 OE2 GLU G 82 65.311 -21.635 50.250 1.00123.81 O +ATOM 12069 N ARG G 83 65.612 -18.836 45.852 1.00125.09 N +ATOM 12070 CA ARG G 83 64.409 -18.430 45.172 1.00109.43 C +ATOM 12071 C ARG G 83 63.267 -19.456 45.331 1.00 94.31 C +ATOM 12072 O ARG G 83 62.114 -19.113 45.094 1.00100.15 O +ATOM 12073 CB ARG G 83 64.727 -18.162 43.691 1.00116.09 C +ATOM 12074 CG ARG G 83 65.836 -17.150 43.465 1.00 97.85 C +ATOM 12075 CD ARG G 83 65.411 -15.757 43.857 1.00102.17 C +ATOM 12076 NE ARG G 83 66.433 -14.829 43.397 1.00120.29 N +ATOM 12077 CZ ARG G 83 67.371 -14.258 44.159 1.00138.48 C +ATOM 12078 NH1 ARG G 83 67.395 -14.420 45.482 1.00 90.10 N +ATOM 12079 NH2 ARG G 83 68.274 -13.464 43.576 1.00188.68 N +ATOM 12080 N GLN G 84 63.564 -20.705 45.701 1.00 77.75 N +ATOM 12081 CA GLN G 84 62.486 -21.702 45.818 1.00 84.94 C +ATOM 12082 C GLN G 84 61.507 -21.256 46.880 1.00 86.74 C +ATOM 12083 O GLN G 84 60.310 -21.308 46.685 1.00129.90 O +ATOM 12084 CB GLN G 84 62.990 -23.125 46.117 1.00 71.62 C +ATOM 12085 CG GLN G 84 62.104 -24.246 45.541 1.00 58.66 C +ATOM 12086 CD GLN G 84 62.587 -25.627 45.908 1.00 64.62 C +ATOM 12087 OE1 GLN G 84 63.788 -25.882 46.009 1.00 79.96 O +ATOM 12088 NE2 GLN G 84 61.653 -26.524 46.169 1.00 90.91 N +ATOM 12089 N GLY G 85 62.001 -20.681 47.950 1.00100.66 N +ATOM 12090 CA GLY G 85 61.087 -20.160 48.971 1.00113.43 C +ATOM 12091 C GLY G 85 61.055 -18.646 49.056 1.00110.86 C +ATOM 12092 O GLY G 85 61.025 -18.091 50.155 1.00124.59 O +ATOM 12093 N LEU G 86 61.085 -17.963 47.908 1.00 97.84 N +ATOM 12094 CA LEU G 86 61.371 -16.505 47.882 1.00 86.00 C +ATOM 12095 C LEU G 86 60.332 -15.717 48.662 1.00 86.64 C +ATOM 12096 O LEU G 86 60.654 -14.729 49.323 1.00 64.87 O +ATOM 12097 CB LEU G 86 61.418 -15.964 46.452 1.00 82.51 C +ATOM 12098 CG LEU G 86 61.483 -14.433 46.196 1.00 56.98 C +ATOM 12099 CD1 LEU G 86 62.718 -13.819 46.776 1.00 54.12 C +ATOM 12100 CD2 LEU G 86 61.460 -14.183 44.693 1.00 70.08 C +ATOM 12101 N GLN G 87 59.095 -16.204 48.639 1.00 96.68 N +ATOM 12102 CA GLN G 87 58.007 -15.491 49.298 1.00109.77 C +ATOM 12103 C GLN G 87 58.248 -15.331 50.827 1.00104.09 C +ATOM 12104 O GLN G 87 58.048 -14.248 51.408 1.00123.56 O +ATOM 12105 CB GLN G 87 56.675 -16.186 48.998 1.00107.73 C +ATOM 12106 CG GLN G 87 55.500 -15.225 48.871 1.00119.53 C +ATOM 12107 CD GLN G 87 55.820 -13.968 48.065 1.00139.77 C +ATOM 12108 OE1 GLN G 87 56.242 -14.041 46.905 1.00177.39 O +ATOM 12109 NE2 GLN G 87 55.611 -12.802 48.674 1.00146.11 N +ATOM 12110 N ASN G 88 58.698 -16.406 51.468 1.00 68.71 N +ATOM 12111 CA ASN G 88 58.955 -16.386 52.893 1.00 49.52 C +ATOM 12112 C ASN G 88 60.069 -15.421 53.161 1.00 47.30 C +ATOM 12113 O ASN G 88 60.174 -14.837 54.264 1.00 70.36 O +ATOM 12114 CB ASN G 88 59.355 -17.768 53.388 1.00 61.43 C +ATOM 12115 CG ASN G 88 58.294 -18.793 53.166 1.00 74.51 C +ATOM 12116 OD1 ASN G 88 57.109 -18.459 53.188 1.00 67.39 O +ATOM 12117 ND2 ASN G 88 58.707 -20.036 52.796 1.00 86.12 N +ATOM 12118 N LEU G 89 61.005 -15.352 52.230 1.00 52.52 N +ATOM 12119 CA LEU G 89 62.247 -14.614 52.470 1.00 98.91 C +ATOM 12120 C LEU G 89 61.834 -13.140 52.532 1.00 97.11 C +ATOM 12121 O LEU G 89 62.286 -12.373 53.406 1.00 85.51 O +ATOM 12122 CB LEU G 89 63.258 -14.910 51.334 1.00102.58 C +ATOM 12123 CG LEU G 89 64.772 -14.779 51.564 1.00 81.93 C +ATOM 12124 CD1 LEU G 89 65.295 -13.639 50.723 1.00 83.05 C +ATOM 12125 CD2 LEU G 89 65.111 -14.530 53.021 1.00 78.80 C +ATOM 12126 N LEU G 90 60.911 -12.792 51.647 1.00 81.55 N +ATOM 12127 CA LEU G 90 60.460 -11.407 51.543 1.00 85.98 C +ATOM 12128 C LEU G 90 59.599 -11.041 52.759 1.00 87.02 C +ATOM 12129 O LEU G 90 59.582 -9.893 53.197 1.00 94.49 O +ATOM 12130 CB LEU G 90 59.680 -11.213 50.251 1.00 77.25 C +ATOM 12131 CG LEU G 90 60.462 -11.494 48.983 1.00 77.07 C +ATOM 12132 CD1 LEU G 90 59.520 -11.735 47.829 1.00 72.46 C +ATOM 12133 CD2 LEU G 90 61.392 -10.325 48.722 1.00100.87 C +ATOM 12134 N ASN G 91 58.901 -12.036 53.303 1.00 69.83 N +ATOM 12135 CA ASN G 91 58.097 -11.847 54.499 1.00 54.79 C +ATOM 12136 C ASN G 91 58.920 -11.595 55.723 1.00 62.34 C +ATOM 12137 O ASN G 91 58.673 -10.648 56.450 1.00 74.07 O +ATOM 12138 CB ASN G 91 57.230 -13.046 54.730 1.00 73.89 C +ATOM 12139 CG ASN G 91 55.806 -12.636 54.907 1.00118.25 C +ATOM 12140 OD1 ASN G 91 55.272 -11.944 54.031 1.00186.79 O +ATOM 12141 ND2 ASN G 91 55.214 -12.919 56.075 1.00138.30 N +ATOM 12142 N GLU G 92 59.954 -12.417 55.935 1.00 97.00 N +ATOM 12143 CA GLU G 92 60.900 -12.201 57.048 1.00 90.07 C +ATOM 12144 C GLU G 92 61.591 -10.832 56.964 1.00 73.55 C +ATOM 12145 O GLU G 92 61.749 -10.131 57.983 1.00 48.75 O +ATOM 12146 CB GLU G 92 61.979 -13.280 57.102 1.00 69.30 C +ATOM 12147 CG GLU G 92 61.620 -14.478 57.960 1.00 66.39 C +ATOM 12148 CD GLU G 92 61.150 -14.110 59.377 1.00 81.20 C +ATOM 12149 OE1 GLU G 92 61.917 -13.426 60.160 1.00 95.36 O +ATOM 12150 OE2 GLU G 92 60.001 -14.517 59.716 1.00 66.36 O +ATOM 12151 N ARG G 93 61.883 -10.414 55.742 1.00 58.23 N +ATOM 12152 CA ARG G 93 62.391 -9.078 55.536 1.00 73.19 C +ATOM 12153 C ARG G 93 61.354 -7.952 55.840 1.00 78.21 C +ATOM 12154 O ARG G 93 61.703 -6.887 56.365 1.00 54.58 O +ATOM 12155 CB ARG G 93 62.972 -8.979 54.124 1.00 79.10 C +ATOM 12156 CG ARG G 93 64.207 -9.853 53.960 1.00 72.87 C +ATOM 12157 CD ARG G 93 64.622 -10.089 52.512 1.00 66.25 C +ATOM 12158 NE ARG G 93 65.755 -9.257 52.127 1.00 61.43 N +ATOM 12159 CZ ARG G 93 65.659 -8.115 51.471 1.00 78.32 C +ATOM 12160 NH1 ARG G 93 64.472 -7.613 51.109 1.00110.51 N +ATOM 12161 NH2 ARG G 93 66.758 -7.467 51.154 1.00 81.02 N +ATOM 12162 N LYS G 94 60.074 -8.205 55.573 1.00 81.81 N +ATOM 12163 CA LYS G 94 59.020 -7.261 55.985 1.00 86.11 C +ATOM 12164 C LYS G 94 58.977 -7.133 57.511 1.00 80.55 C +ATOM 12165 O LYS G 94 58.820 -6.028 58.044 1.00 63.89 O +ATOM 12166 CB LYS G 94 57.648 -7.725 55.504 1.00 93.15 C +ATOM 12167 CG LYS G 94 57.246 -7.274 54.109 1.00104.66 C +ATOM 12168 CD LYS G 94 55.957 -7.974 53.694 1.00107.91 C +ATOM 12169 CE LYS G 94 55.234 -7.262 52.565 1.00114.95 C +ATOM 12170 NZ LYS G 94 54.197 -8.160 51.983 1.00136.14 N +ATOM 12171 N ILE G 95 59.133 -8.271 58.199 1.00 69.87 N +ATOM 12172 CA ILE G 95 59.017 -8.301 59.650 1.00 66.36 C +ATOM 12173 C ILE G 95 60.210 -7.625 60.314 1.00 85.03 C +ATOM 12174 O ILE G 95 60.033 -6.852 61.299 1.00 81.99 O +ATOM 12175 CB ILE G 95 58.916 -9.707 60.237 1.00 52.06 C +ATOM 12176 CG1 ILE G 95 57.870 -10.521 59.510 1.00 69.31 C +ATOM 12177 CG2 ILE G 95 58.490 -9.575 61.682 1.00 60.48 C +ATOM 12178 CD1 ILE G 95 57.440 -11.790 60.206 1.00 82.88 C +ATOM 12179 N ILE G 96 61.391 -7.879 59.739 1.00 76.33 N +ATOM 12180 CA ILE G 96 62.580 -7.132 60.088 1.00 78.75 C +ATOM 12181 C ILE G 96 62.342 -5.629 59.952 1.00 90.91 C +ATOM 12182 O ILE G 96 62.489 -4.882 60.929 1.00118.30 O +ATOM 12183 CB ILE G 96 63.798 -7.520 59.230 1.00 74.54 C +ATOM 12184 CG1 ILE G 96 64.176 -8.960 59.506 1.00 91.86 C +ATOM 12185 CG2 ILE G 96 64.991 -6.632 59.577 1.00 63.62 C +ATOM 12186 CD1 ILE G 96 65.413 -9.400 58.754 1.00123.27 C +ATOM 12187 N ARG G 97 62.006 -5.179 58.744 1.00 79.23 N +ATOM 12188 CA ARG G 97 61.884 -3.745 58.480 1.00 89.97 C +ATOM 12189 C ARG G 97 60.820 -3.106 59.374 1.00100.92 C +ATOM 12190 O ARG G 97 60.925 -1.922 59.738 1.00120.66 O +ATOM 12191 CB ARG G 97 61.551 -3.483 57.012 1.00 97.74 C +ATOM 12192 CG ARG G 97 62.716 -2.983 56.178 1.00103.36 C +ATOM 12193 CD ARG G 97 62.273 -2.684 54.753 1.00108.17 C +ATOM 12194 NE ARG G 97 62.196 -3.898 53.942 1.00 92.50 N +ATOM 12195 CZ ARG G 97 63.148 -4.293 53.092 1.00116.52 C +ATOM 12196 NH1 ARG G 97 64.290 -3.600 52.931 1.00111.78 N +ATOM 12197 NH2 ARG G 97 62.968 -5.402 52.397 1.00147.41 N +ATOM 12198 N ALA G 98 59.784 -3.873 59.707 1.00 75.41 N +ATOM 12199 CA ALA G 98 58.753 -3.373 60.587 1.00 72.71 C +ATOM 12200 C ALA G 98 59.259 -3.254 62.029 1.00 90.11 C +ATOM 12201 O ALA G 98 58.791 -2.413 62.818 1.00 74.51 O +ATOM 12202 CB ALA G 98 57.551 -4.272 60.508 1.00 59.30 C +ATOM 12203 N ALA G 99 60.218 -4.110 62.364 1.00111.35 N +ATOM 12204 CA ALA G 99 60.775 -4.146 63.708 1.00107.31 C +ATOM 12205 C ALA G 99 61.582 -2.888 63.991 1.00 61.25 C +ATOM 12206 O ALA G 99 61.457 -2.279 65.042 1.00 32.60 O +ATOM 12207 CB ALA G 99 61.626 -5.419 63.901 1.00134.59 C +ATOM 12208 N GLN G 100 62.485 -2.581 63.074 1.00 64.60 N +ATOM 12209 CA GLN G 100 63.615 -1.693 63.390 1.00107.67 C +ATOM 12210 C GLN G 100 63.497 -0.337 62.724 1.00101.39 C +ATOM 12211 O GLN G 100 64.404 0.498 62.836 1.00 85.66 O +ATOM 12212 CB GLN G 100 64.979 -2.329 63.029 1.00120.82 C +ATOM 12213 CG GLN G 100 65.016 -3.064 61.701 1.00106.31 C +ATOM 12214 CD GLN G 100 66.045 -4.191 61.644 1.00 96.27 C +ATOM 12215 OE1 GLN G 100 66.028 -5.153 62.445 1.00 52.81 O +ATOM 12216 NE2 GLN G 100 66.953 -4.071 60.686 1.00101.73 N +ATOM 12217 N GLU G 101 62.349 -0.093 62.099 1.00101.00 N +ATOM 12218 CA GLU G 101 62.112 1.194 61.432 1.00106.27 C +ATOM 12219 C GLU G 101 62.045 2.403 62.389 1.00 92.20 C +ATOM 12220 O GLU G 101 62.291 3.522 61.985 1.00 86.95 O +ATOM 12221 CB GLU G 101 60.852 1.119 60.563 1.00 99.76 C +ATOM 12222 CG GLU G 101 59.606 0.639 61.291 1.00105.42 C +ATOM 12223 CD GLU G 101 58.369 0.657 60.410 1.00110.18 C +ATOM 12224 OE1 GLU G 101 58.528 0.724 59.171 1.00134.55 O +ATOM 12225 OE2 GLU G 101 57.237 0.612 60.943 1.00 89.34 O +ATOM 12226 N ASN G 102 61.717 2.166 63.650 1.00 80.72 N +ATOM 12227 CA ASN G 102 61.551 3.251 64.596 1.00 64.65 C +ATOM 12228 C ASN G 102 62.817 3.565 65.356 1.00 78.35 C +ATOM 12229 O ASN G 102 62.823 4.427 66.236 1.00107.02 O +ATOM 12230 CB ASN G 102 60.415 2.918 65.556 1.00 62.11 C +ATOM 12231 CG ASN G 102 59.085 3.010 64.879 1.00 80.15 C +ATOM 12232 OD1 ASN G 102 58.546 4.107 64.658 1.00106.09 O +ATOM 12233 ND2 ASN G 102 58.545 1.856 64.501 1.00103.78 N +ATOM 12234 N GLY G 103 63.868 2.783 65.133 1.00 93.20 N +ATOM 12235 CA GLY G 103 65.108 2.943 65.923 1.00120.06 C +ATOM 12236 C GLY G 103 64.986 2.802 67.447 1.00 90.47 C +ATOM 12237 O GLY G 103 65.655 3.476 68.208 1.00 81.25 O +ATOM 12238 N THR G 104 64.119 1.911 67.873 1.00 93.61 N +ATOM 12239 CA THR G 104 64.088 1.508 69.240 1.00101.26 C +ATOM 12240 C THR G 104 64.800 0.183 69.386 1.00 98.70 C +ATOM 12241 O THR G 104 65.333 -0.091 70.449 1.00130.99 O +ATOM 12242 CB THR G 104 62.637 1.405 69.782 1.00139.34 C +ATOM 12243 OG1 THR G 104 61.895 0.371 69.115 1.00130.32 O +ATOM 12244 CG2 THR G 104 61.905 2.741 69.608 1.00158.30 C +ATOM 12245 N VAL G 105 64.786 -0.652 68.350 1.00 91.55 N +ATOM 12246 CA VAL G 105 65.292 -2.006 68.487 1.00108.01 C +ATOM 12247 C VAL G 105 66.754 -1.992 68.966 1.00134.60 C +ATOM 12248 O VAL G 105 67.584 -1.183 68.521 1.00138.13 O +ATOM 12249 CB VAL G 105 65.117 -2.866 67.200 1.00132.01 C +ATOM 12250 CG1 VAL G 105 66.260 -3.881 67.014 1.00168.95 C +ATOM 12251 CG2 VAL G 105 63.784 -3.612 67.216 1.00119.76 C +ATOM 12252 N ALA G 106 67.053 -2.932 69.866 1.00139.89 N +ATOM 12253 CA ALA G 106 68.337 -3.016 70.544 1.00117.95 C +ATOM 12254 C ALA G 106 69.472 -3.222 69.540 1.00106.36 C +ATOM 12255 O ALA G 106 69.407 -4.106 68.680 1.00112.22 O +ATOM 12256 CB ALA G 106 68.303 -4.148 71.582 1.00111.31 C +ATOM 12257 N ILE G 107 70.535 -2.447 69.697 1.00104.27 N +ATOM 12258 CA ILE G 107 71.648 -2.521 68.755 1.00110.85 C +ATOM 12259 C ILE G 107 72.313 -3.899 68.605 1.00120.17 C +ATOM 12260 O ILE G 107 72.848 -4.214 67.551 1.00112.85 O +ATOM 12261 CB ILE G 107 72.672 -1.406 68.870 1.00109.49 C +ATOM 12262 CG1 ILE G 107 72.540 -0.644 70.184 1.00115.07 C +ATOM 12263 CG2 ILE G 107 72.455 -0.494 67.664 1.00 98.60 C +ATOM 12264 CD1 ILE G 107 72.842 -1.421 71.468 1.00102.88 C +ATOM 12265 N ASN G 108 72.296 -4.690 69.676 1.00129.69 N +ATOM 12266 CA ASN G 108 72.774 -6.077 69.633 1.00142.43 C +ATOM 12267 C ASN G 108 71.843 -6.956 68.801 1.00139.99 C +ATOM 12268 O ASN G 108 72.290 -7.874 68.108 1.00175.08 O +ATOM 12269 CB ASN G 108 72.858 -6.669 71.043 1.00143.48 C +ATOM 12270 CG ASN G 108 73.163 -5.626 72.095 1.00163.46 C +ATOM 12271 OD1 ASN G 108 74.325 -5.314 72.357 1.00222.41 O +ATOM 12272 ND2 ASN G 108 72.119 -5.069 72.697 1.00170.27 N +ATOM 12273 N ASN G 109 70.552 -6.659 68.879 1.00103.97 N +ATOM 12274 CA ASN G 109 69.536 -7.461 68.234 1.00103.91 C +ATOM 12275 C ASN G 109 69.302 -7.072 66.770 1.00102.48 C +ATOM 12276 O ASN G 109 68.691 -7.832 65.996 1.00144.89 O +ATOM 12277 CB ASN G 109 68.233 -7.345 69.023 1.00123.92 C +ATOM 12278 CG ASN G 109 67.803 -8.662 69.617 1.00148.83 C +ATOM 12279 OD1 ASN G 109 66.775 -9.219 69.229 1.00192.57 O +ATOM 12280 ND2 ASN G 109 68.611 -9.198 70.525 1.00152.76 N +ATOM 12281 N ARG G 110 69.765 -5.877 66.402 1.00 89.18 N +ATOM 12282 CA ARG G 110 69.484 -5.265 65.087 1.00 78.52 C +ATOM 12283 C ARG G 110 69.930 -6.172 63.930 1.00 71.98 C +ATOM 12284 O ARG G 110 71.031 -6.728 63.972 1.00111.56 O +ATOM 12285 CB ARG G 110 70.225 -3.920 64.993 1.00 78.65 C +ATOM 12286 CG ARG G 110 69.652 -2.943 63.989 1.00 88.99 C +ATOM 12287 CD ARG G 110 69.820 -1.507 64.444 1.00110.14 C +ATOM 12288 NE ARG G 110 71.095 -0.967 63.959 1.00111.17 N +ATOM 12289 CZ ARG G 110 71.225 0.097 63.164 1.00133.61 C +ATOM 12290 NH1 ARG G 110 70.155 0.784 62.735 1.00152.35 N +ATOM 12291 NH2 ARG G 110 72.439 0.495 62.798 1.00116.33 N +ATOM 12292 N ILE G 111 69.092 -6.325 62.909 1.00 59.01 N +ATOM 12293 CA ILE G 111 69.489 -7.059 61.714 1.00 65.68 C +ATOM 12294 C ILE G 111 69.670 -6.110 60.563 1.00 84.56 C +ATOM 12295 O ILE G 111 68.703 -5.497 60.127 1.00101.00 O +ATOM 12296 CB ILE G 111 68.452 -8.099 61.305 1.00 84.31 C +ATOM 12297 CG1 ILE G 111 68.341 -9.174 62.403 1.00103.69 C +ATOM 12298 CG2 ILE G 111 68.845 -8.747 59.980 1.00 97.17 C +ATOM 12299 CD1 ILE G 111 67.151 -10.129 62.265 1.00 75.84 C +ATOM 12300 N PRO G 112 70.917 -5.972 60.061 1.00106.33 N +ATOM 12301 CA PRO G 112 71.170 -5.062 58.954 1.00 95.67 C +ATOM 12302 C PRO G 112 70.699 -5.658 57.611 1.00107.51 C +ATOM 12303 O PRO G 112 71.048 -6.798 57.259 1.00 84.69 O +ATOM 12304 CB PRO G 112 72.681 -4.904 58.986 1.00 87.79 C +ATOM 12305 CG PRO G 112 73.176 -6.233 59.461 1.00 99.70 C +ATOM 12306 CD PRO G 112 72.093 -6.822 60.334 1.00113.66 C +ATOM 12307 N LEU G 113 69.892 -4.884 56.887 1.00104.76 N +ATOM 12308 CA LEU G 113 69.270 -5.343 55.654 1.00 81.89 C +ATOM 12309 C LEU G 113 69.896 -4.685 54.435 1.00 78.59 C +ATOM 12310 O LEU G 113 70.203 -3.478 54.427 1.00 82.16 O +ATOM 12311 CB LEU G 113 67.764 -5.056 55.662 1.00 64.76 C +ATOM 12312 CG LEU G 113 66.922 -6.124 56.334 1.00 62.30 C +ATOM 12313 CD1 LEU G 113 65.492 -5.715 56.134 1.00 85.88 C +ATOM 12314 CD2 LEU G 113 67.137 -7.519 55.757 1.00 61.63 C +ATOM 12315 N GLN G 114 69.953 -5.448 53.363 1.00 67.58 N +ATOM 12316 CA GLN G 114 70.259 -4.846 52.080 1.00 83.83 C +ATOM 12317 C GLN G 114 69.420 -5.603 51.097 1.00 91.67 C +ATOM 12318 O GLN G 114 69.213 -6.806 51.265 1.00147.21 O +ATOM 12319 CB GLN G 114 71.736 -4.974 51.731 1.00104.24 C +ATOM 12320 CG GLN G 114 72.269 -3.919 50.769 1.00100.48 C +ATOM 12321 CD GLN G 114 73.174 -4.544 49.734 1.00116.48 C +ATOM 12322 OE1 GLN G 114 73.025 -4.262 48.557 1.00 68.98 O +ATOM 12323 NE2 GLN G 114 74.005 -5.516 50.154 1.00150.66 N +ATOM 12324 N SER G 115 68.980 -4.923 50.049 1.00101.37 N +ATOM 12325 CA SER G 115 68.188 -5.559 49.006 1.00 99.52 C +ATOM 12326 C SER G 115 69.004 -6.801 48.501 1.00 70.27 C +ATOM 12327 O SER G 115 70.140 -6.817 48.460 1.00 39.11 O +ATOM 12328 CB SER G 115 67.800 -4.513 47.915 1.00 85.61 C +ATOM 12329 OG SER G 115 68.944 -3.903 47.380 1.00115.65 O +ATOM 12330 N LEU G 116 68.331 -7.733 47.927 1.00 67.75 N +ATOM 12331 CA LEU G 116 68.675 -9.125 47.775 1.00 64.61 C +ATOM 12332 C LEU G 116 69.806 -9.280 46.770 1.00 69.09 C +ATOM 12333 O LEU G 116 69.682 -8.863 45.618 1.00 83.64 O +ATOM 12334 CB LEU G 116 67.386 -9.854 47.302 1.00 75.21 C +ATOM 12335 CG LEU G 116 66.211 -9.790 48.294 1.00 76.76 C +ATOM 12336 CD1 LEU G 116 65.282 -8.587 48.013 1.00 76.25 C +ATOM 12337 CD2 LEU G 116 65.436 -11.100 48.228 1.00 70.72 C +ATOM 12338 N THR G 117 70.784 -10.101 47.126 1.00 85.24 N +ATOM 12339 CA THR G 117 71.828 -10.510 46.190 1.00111.94 C +ATOM 12340 C THR G 117 71.234 -11.131 44.935 1.00102.95 C +ATOM 12341 O THR G 117 70.390 -12.023 45.013 1.00 85.94 O +ATOM 12342 CB THR G 117 72.801 -11.556 46.799 1.00144.95 C +ATOM 12343 OG1 THR G 117 73.280 -11.097 48.063 1.00160.37 O +ATOM 12344 CG2 THR G 117 73.997 -11.768 45.889 1.00166.58 C +ATOM 12345 N ALA G 118 71.713 -10.681 43.778 1.00127.79 N +ATOM 12346 CA ALA G 118 71.090 -11.021 42.500 1.00108.04 C +ATOM 12347 C ALA G 118 72.030 -11.856 41.662 1.00 69.55 C +ATOM 12348 O ALA G 118 73.189 -11.517 41.483 1.00 55.43 O +ATOM 12349 CB ALA G 118 70.663 -9.753 41.752 1.00106.96 C +ATOM 12350 N ALA G 119 71.439 -12.831 41.015 1.00 66.71 N +ATOM 12351 CA ALA G 119 72.152 -13.732 40.154 1.00 80.77 C +ATOM 12352 C ALA G 119 72.435 -13.158 38.742 1.00 78.32 C +ATOM 12353 O ALA G 119 71.631 -12.397 38.201 1.00 96.65 O +ATOM 12354 CB ALA G 119 71.351 -15.028 40.059 1.00 94.53 C +ATOM 12355 N ASN G 120 73.463 -13.675 38.088 1.00 80.49 N +ATOM 12356 CA ASN G 120 73.664 -13.379 36.686 1.00 81.32 C +ATOM 12357 C ASN G 120 73.114 -14.468 35.759 1.00 70.04 C +ATOM 12358 O ASN G 120 72.566 -14.180 34.677 1.00 88.37 O +ATOM 12359 CB ASN G 120 75.150 -13.159 36.392 1.00102.48 C +ATOM 12360 CG ASN G 120 75.419 -12.787 34.929 1.00132.52 C +ATOM 12361 OD1 ASN G 120 74.628 -12.082 34.264 1.00 85.48 O +ATOM 12362 ND2 ASN G 120 76.536 -13.301 34.405 1.00150.84 N +ATOM 12363 N ILE G 121 73.439 -15.713 36.060 1.00 57.09 N +ATOM 12364 CA ILE G 121 72.934 -16.787 35.255 1.00 62.95 C +ATOM 12365 C ILE G 121 71.933 -17.505 36.140 1.00 80.62 C +ATOM 12366 O ILE G 121 72.165 -17.671 37.328 1.00 65.79 O +ATOM 12367 CB ILE G 121 74.048 -17.751 34.720 1.00 58.83 C +ATOM 12368 CG1 ILE G 121 74.638 -18.645 35.835 1.00 51.97 C +ATOM 12369 CG2 ILE G 121 75.143 -16.982 33.984 1.00 45.26 C +ATOM 12370 CD1 ILE G 121 74.252 -20.116 35.724 1.00 55.00 C +ATOM 12371 N MET G 122 70.828 -17.957 35.550 1.00 71.47 N +ATOM 12372 CA MET G 122 69.974 -18.891 36.258 1.00 54.22 C +ATOM 12373 C MET G 122 69.782 -20.154 35.462 1.00 50.00 C +ATOM 12374 O MET G 122 69.901 -20.156 34.234 1.00 43.39 O +ATOM 12375 CB MET G 122 68.656 -18.238 36.556 1.00 67.59 C +ATOM 12376 CG MET G 122 67.890 -17.716 35.347 1.00 77.13 C +ATOM 12377 SD MET G 122 66.118 -17.727 35.682 1.00105.60 S +ATOM 12378 CE MET G 122 65.459 -18.370 34.143 1.00 52.57 C +ATOM 12379 N VAL G 123 69.740 -21.271 36.166 1.00 63.46 N +ATOM 12380 CA VAL G 123 69.722 -22.578 35.507 1.00 83.25 C +ATOM 12381 C VAL G 123 68.431 -23.251 35.887 1.00 88.39 C +ATOM 12382 O VAL G 123 68.147 -23.445 37.054 1.00 61.61 O +ATOM 12383 CB VAL G 123 70.916 -23.506 35.876 1.00 80.93 C +ATOM 12384 CG1 VAL G 123 71.260 -23.403 37.343 1.00 89.04 C +ATOM 12385 CG2 VAL G 123 70.618 -24.963 35.511 1.00 98.06 C +ATOM 12386 N GLU G 124 67.677 -23.653 34.873 1.00106.64 N +ATOM 12387 CA GLU G 124 66.492 -24.475 35.092 1.00120.16 C +ATOM 12388 C GLU G 124 66.503 -25.705 34.213 1.00118.69 C +ATOM 12389 O GLU G 124 67.370 -25.869 33.364 1.00139.11 O +ATOM 12390 CB GLU G 124 65.227 -23.684 34.814 1.00123.96 C +ATOM 12391 CG GLU G 124 65.373 -22.595 33.766 1.00123.43 C +ATOM 12392 CD GLU G 124 64.261 -21.571 33.860 1.00129.19 C +ATOM 12393 OE1 GLU G 124 63.790 -21.283 34.983 1.00 70.89 O +ATOM 12394 OE2 GLU G 124 63.778 -21.148 32.789 1.00207.40 O +ATOM 12395 N GLY G 125 65.569 -26.605 34.476 1.00105.97 N +ATOM 12396 CA GLY G 125 65.567 -27.892 33.814 1.00 99.13 C +ATOM 12397 C GLY G 125 64.312 -28.674 34.096 1.00100.68 C +ATOM 12398 O GLY G 125 63.344 -28.149 34.648 1.00108.85 O +ATOM 12399 N SER G 126 64.364 -29.972 33.831 1.00101.99 N +ATOM 12400 CA SER G 126 63.196 -30.821 34.034 1.00101.03 C +ATOM 12401 C SER G 126 63.595 -32.279 34.128 1.00 75.01 C +ATOM 12402 O SER G 126 64.601 -32.674 33.572 1.00 63.32 O +ATOM 12403 CB SER G 126 62.257 -30.678 32.853 1.00131.19 C +ATOM 12404 OG SER G 126 62.323 -29.378 32.271 1.00173.50 O +ATOM 12405 N ILE G 127 62.863 -33.052 34.916 1.00 65.31 N +ATOM 12406 CA ILE G 127 63.003 -34.464 34.839 1.00 70.79 C +ATOM 12407 C ILE G 127 62.238 -34.831 33.576 1.00 90.58 C +ATOM 12408 O ILE G 127 61.029 -34.995 33.577 1.00 75.84 O +ATOM 12409 CB ILE G 127 62.466 -35.208 36.074 1.00 91.33 C +ATOM 12410 CG1 ILE G 127 63.329 -34.897 37.297 1.00117.42 C +ATOM 12411 CG2 ILE G 127 62.453 -36.726 35.846 1.00121.46 C +ATOM 12412 CD1 ILE G 127 62.561 -34.925 38.611 1.00139.89 C +ATOM 12413 N ILE G 128 62.997 -35.085 32.526 1.00117.26 N +ATOM 12414 CA ILE G 128 62.474 -35.610 31.300 1.00109.83 C +ATOM 12415 C ILE G 128 62.487 -37.150 31.417 1.00 89.16 C +ATOM 12416 O ILE G 128 63.527 -37.803 31.235 1.00123.65 O +ATOM 12417 CB ILE G 128 63.464 -35.378 30.141 1.00125.85 C +ATOM 12418 CG1 ILE G 128 64.113 -33.986 30.005 1.00113.40 C +ATOM 12419 CG2 ILE G 128 62.754 -35.651 28.857 1.00128.65 C +ATOM 12420 CD1 ILE G 128 65.480 -34.078 29.328 1.00127.94 C +ATOM 12421 N GLY G 129 61.351 -37.734 31.715 1.00 59.20 N +ATOM 12422 CA GLY G 129 61.154 -39.133 31.447 1.00 63.03 C +ATOM 12423 C GLY G 129 61.570 -40.049 32.574 1.00 78.84 C +ATOM 12424 O GLY G 129 62.666 -39.959 33.142 1.00 76.77 O +ATOM 12425 N TYR G 130 60.702 -41.023 32.826 1.00131.53 N +ATOM 12426 CA TYR G 130 61.050 -42.235 33.574 1.00131.92 C +ATOM 12427 C TYR G 130 60.343 -43.387 32.899 1.00127.08 C +ATOM 12428 O TYR G 130 59.119 -43.448 32.907 1.00144.63 O +ATOM 12429 CB TYR G 130 60.590 -42.109 35.031 1.00121.70 C +ATOM 12430 CG TYR G 130 60.767 -43.338 35.894 1.00113.32 C +ATOM 12431 CD1 TYR G 130 60.023 -44.490 35.655 1.00114.38 C +ATOM 12432 CD2 TYR G 130 61.651 -43.323 36.982 1.00119.90 C +ATOM 12433 CE1 TYR G 130 60.159 -45.600 36.470 1.00147.35 C +ATOM 12434 CE2 TYR G 130 61.820 -44.430 37.778 1.00122.13 C +ATOM 12435 CZ TYR G 130 61.081 -45.567 37.521 1.00156.70 C +ATOM 12436 OH TYR G 130 61.226 -46.648 38.360 1.00196.69 O +ATOM 12437 N GLU G 131 61.092 -44.212 32.181 1.00115.76 N +ATOM 12438 CA GLU G 131 60.520 -45.433 31.616 1.00139.60 C +ATOM 12439 C GLU G 131 60.823 -46.586 32.562 1.00122.56 C +ATOM 12440 O GLU G 131 61.846 -46.574 33.231 1.00118.49 O +ATOM 12441 CB GLU G 131 61.090 -45.682 30.219 1.00138.56 C +ATOM 12442 CG GLU G 131 60.419 -46.798 29.425 1.00115.26 C +ATOM 12443 CD GLU G 131 59.218 -46.340 28.602 1.00113.97 C +ATOM 12444 OE1 GLU G 131 59.179 -45.155 28.176 1.00 83.72 O +ATOM 12445 OE2 GLU G 131 58.311 -47.174 28.382 1.00127.39 O +ATOM 12446 N SER G 132 59.913 -47.552 32.642 1.00114.64 N +ATOM 12447 CA SER G 132 60.006 -48.595 33.660 1.00108.17 C +ATOM 12448 C SER G 132 60.117 -49.998 33.038 1.00139.78 C +ATOM 12449 O SER G 132 59.465 -50.299 32.038 1.00161.03 O +ATOM 12450 CB SER G 132 58.808 -48.536 34.605 1.00 92.50 C +ATOM 12451 OG SER G 132 57.984 -49.694 34.460 1.00 84.81 O +ATOM 12452 N ASN G 133 60.917 -50.859 33.666 1.00144.96 N +ATOM 12453 CA ASN G 133 61.318 -52.146 33.068 1.00118.51 C +ATOM 12454 C ASN G 133 61.737 -51.980 31.615 1.00116.35 C +ATOM 12455 O ASN G 133 61.191 -52.618 30.721 1.00 95.65 O +ATOM 12456 CB ASN G 133 60.202 -53.171 33.166 1.00 93.40 C +ATOM 12457 CG ASN G 133 59.801 -53.445 34.592 1.00114.41 C +ATOM 12458 OD1 ASN G 133 60.611 -53.326 35.533 1.00137.21 O +ATOM 12459 ND2 ASN G 133 58.537 -53.773 34.778 1.00128.17 N +ATOM 12460 N VAL G 134 62.730 -51.121 31.404 1.00122.27 N +ATOM 12461 CA VAL G 134 63.276 -50.877 30.084 1.00124.78 C +ATOM 12462 C VAL G 134 63.993 -52.151 29.642 1.00132.94 C +ATOM 12463 O VAL G 134 63.952 -52.523 28.465 1.00141.39 O +ATOM 12464 CB VAL G 134 64.245 -49.673 30.097 1.00144.46 C +ATOM 12465 CG1 VAL G 134 64.752 -49.362 28.692 1.00143.71 C +ATOM 12466 CG2 VAL G 134 63.559 -48.441 30.686 1.00152.74 C +ATOM 12467 N LYS G 135 64.599 -52.842 30.605 1.00136.14 N +ATOM 12468 CA LYS G 135 65.011 -54.228 30.401 1.00140.76 C +ATOM 12469 C LYS G 135 64.661 -55.088 31.602 1.00152.45 C +ATOM 12470 O LYS G 135 64.498 -54.592 32.732 1.00151.92 O +ATOM 12471 CB LYS G 135 66.514 -54.305 30.145 1.00171.28 C +ATOM 12472 CG LYS G 135 66.950 -53.584 28.882 1.00192.08 C +ATOM 12473 CD LYS G 135 68.459 -53.605 28.753 1.00235.33 C +ATOM 12474 CE LYS G 135 68.920 -52.879 27.505 1.00238.03 C +ATOM 12475 NZ LYS G 135 70.287 -53.322 27.127 1.00292.56 N +ATOM 12476 N SER G 136 64.603 -56.395 31.366 1.00180.39 N +ATOM 12477 CA SER G 136 64.320 -57.354 32.431 1.00206.86 C +ATOM 12478 C SER G 136 64.710 -58.775 32.035 1.00178.05 C +ATOM 12479 O SER G 136 64.793 -59.091 30.851 1.00167.88 O +ATOM 12480 CB SER G 136 62.843 -57.295 32.823 1.00219.21 C +ATOM 12481 OG SER G 136 62.231 -58.572 32.734 1.00221.99 O +ATOM 12482 N GLY G 137 64.960 -59.617 33.037 1.00132.11 N +ATOM 12483 CA GLY G 137 65.296 -61.010 32.782 1.00145.80 C +ATOM 12484 C GLY G 137 65.278 -61.885 34.019 1.00150.68 C +ATOM 12485 O GLY G 137 65.009 -61.416 35.122 1.00123.66 O +ATOM 12486 N GLY G 138 65.500 -63.182 33.820 1.00177.19 N +ATOM 12487 CA GLY G 138 65.480 -64.136 34.921 1.00189.53 C +ATOM 12488 C GLY G 138 66.086 -65.474 34.556 1.00197.40 C +ATOM 12489 O GLY G 138 65.960 -65.933 33.417 1.00179.01 O +ATOM 12490 N VAL G 139 66.747 -66.097 35.530 1.00188.38 N +ATOM 12491 CA VAL G 139 67.323 -67.429 35.353 1.00157.64 C +ATOM 12492 C VAL G 139 67.094 -68.269 36.605 1.00118.81 C +ATOM 12493 O VAL G 139 67.454 -67.865 37.708 1.00 93.17 O +ATOM 12494 CB VAL G 139 68.838 -67.366 35.072 1.00147.33 C +ATOM 12495 CG1 VAL G 139 69.410 -68.767 35.023 1.00157.45 C +ATOM 12496 CG2 VAL G 139 69.124 -66.627 33.769 1.00139.15 C +ATOM 12497 N GLY G 140 66.495 -69.442 36.417 1.00123.19 N +ATOM 12498 CA GLY G 140 66.188 -70.336 37.527 1.00146.32 C +ATOM 12499 C GLY G 140 66.178 -71.811 37.167 1.00162.44 C +ATOM 12500 O GLY G 140 65.801 -72.194 36.058 1.00182.29 O +ATOM 12501 N ALA G 141 66.581 -72.645 38.121 1.00149.61 N +ATOM 12502 CA ALA G 141 66.588 -74.089 37.915 1.00116.85 C +ATOM 12503 C ALA G 141 66.245 -74.837 39.195 1.00119.82 C +ATOM 12504 O ALA G 141 66.634 -74.445 40.300 1.00130.43 O +ATOM 12505 CB ALA G 141 67.933 -74.542 37.379 1.00106.77 C +ATOM 12506 N ARG G 142 65.473 -75.901 39.045 1.00131.37 N +ATOM 12507 CA ARG G 142 65.236 -76.809 40.152 1.00139.89 C +ATOM 12508 C ARG G 142 65.565 -78.217 39.701 1.00166.24 C +ATOM 12509 O ARG G 142 65.362 -78.570 38.537 1.00177.96 O +ATOM 12510 CB ARG G 142 63.793 -76.724 40.664 1.00126.90 C +ATOM 12511 CG ARG G 142 63.546 -77.601 41.884 1.00123.85 C +ATOM 12512 CD ARG G 142 62.693 -76.913 42.928 1.00147.12 C +ATOM 12513 NE ARG G 142 61.277 -77.007 42.591 1.00162.81 N +ATOM 12514 CZ ARG G 142 60.341 -76.154 42.994 1.00173.50 C +ATOM 12515 NH1 ARG G 142 60.651 -75.129 43.780 1.00200.62 N +ATOM 12516 NH2 ARG G 142 59.074 -76.340 42.633 1.00149.45 N +ATOM 12517 N TYR G 143 66.142 -78.989 40.615 1.00181.34 N +ATOM 12518 CA TYR G 143 66.664 -80.307 40.293 1.00162.99 C +ATOM 12519 C TYR G 143 66.116 -81.263 41.343 1.00114.92 C +ATOM 12520 O TYR G 143 66.821 -82.179 41.774 1.00 87.18 O +ATOM 12521 CB TYR G 143 68.205 -80.274 40.303 1.00154.99 C +ATOM 12522 CG TYR G 143 68.888 -81.527 39.838 1.00164.20 C +ATOM 12523 CD1 TYR G 143 68.798 -81.920 38.518 1.00175.95 C +ATOM 12524 CD2 TYR G 143 69.669 -82.293 40.705 1.00160.25 C +ATOM 12525 CE1 TYR G 143 69.454 -83.054 38.060 1.00170.10 C +ATOM 12526 CE2 TYR G 143 70.282 -83.460 40.271 1.00167.75 C +ATOM 12527 CZ TYR G 143 70.173 -83.833 38.947 1.00164.31 C +ATOM 12528 OH TYR G 143 70.799 -84.973 38.510 1.00165.91 O +ATOM 12529 N GLY G 145 64.913 -81.715 43.727 1.00142.39 N +ATOM 12530 CA GLY G 145 64.571 -81.278 45.069 1.00166.08 C +ATOM 12531 C GLY G 145 65.117 -79.913 45.470 1.00199.64 C +ATOM 12532 O GLY G 145 64.518 -79.235 46.292 1.00168.43 O +ATOM 12533 N ILE G 146 66.198 -79.469 44.833 1.00242.13 N +ATOM 12534 CA ILE G 146 66.887 -78.227 45.208 1.00230.13 C +ATOM 12535 C ILE G 146 66.747 -77.200 44.084 1.00206.10 C +ATOM 12536 O ILE G 146 66.898 -77.554 42.902 1.00276.60 O +ATOM 12537 CB ILE G 146 68.387 -78.484 45.502 1.00242.72 C +ATOM 12538 CG1 ILE G 146 68.566 -79.814 46.251 1.00243.68 C +ATOM 12539 CG2 ILE G 146 68.985 -77.338 46.308 1.00228.42 C +ATOM 12540 CD1 ILE G 146 68.922 -80.987 45.361 1.00217.59 C +ATOM 12541 N GLY G 147 66.468 -75.939 44.425 1.00122.63 N +ATOM 12542 CA GLY G 147 66.283 -74.930 43.378 1.00121.80 C +ATOM 12543 C GLY G 147 66.683 -73.511 43.728 1.00121.91 C +ATOM 12544 O GLY G 147 66.719 -73.130 44.886 1.00 82.93 O +ATOM 12545 N ALA G 148 67.030 -72.733 42.705 1.00153.41 N +ATOM 12546 CA ALA G 148 67.333 -71.315 42.883 1.00143.80 C +ATOM 12547 C ALA G 148 66.966 -70.538 41.635 1.00152.19 C +ATOM 12548 O ALA G 148 66.653 -71.118 40.578 1.00121.88 O +ATOM 12549 CB ALA G 148 68.803 -71.105 43.205 1.00133.73 C +ATOM 12550 N ASP G 149 66.929 -69.219 41.783 1.00167.58 N +ATOM 12551 CA ASP G 149 66.587 -68.351 40.665 1.00174.40 C +ATOM 12552 C ASP G 149 66.942 -66.911 40.993 1.00127.60 C +ATOM 12553 O ASP G 149 66.838 -66.490 42.139 1.00 73.36 O +ATOM 12554 CB ASP G 149 65.091 -68.483 40.279 1.00204.21 C +ATOM 12555 CG ASP G 149 64.180 -67.682 41.173 1.00190.85 C +ATOM 12556 OD1 ASP G 149 63.943 -68.127 42.306 1.00239.17 O +ATOM 12557 OD2 ASP G 149 63.677 -66.645 40.720 1.00124.93 O +ATOM 12558 N THR G 150 67.323 -66.156 39.970 1.00138.05 N +ATOM 12559 CA THR G 150 67.350 -64.707 40.083 1.00149.46 C +ATOM 12560 C THR G 150 66.474 -64.071 39.014 1.00182.09 C +ATOM 12561 O THR G 150 66.192 -64.666 37.969 1.00191.71 O +ATOM 12562 CB THR G 150 68.769 -64.136 39.960 1.00127.59 C +ATOM 12563 OG1 THR G 150 69.316 -64.496 38.687 1.00120.87 O +ATOM 12564 CG2 THR G 150 69.649 -64.653 41.076 1.00118.47 C +ATOM 12565 N GLN G 151 66.000 -62.870 39.317 1.00193.77 N +ATOM 12566 CA GLN G 151 65.243 -62.069 38.376 1.00186.97 C +ATOM 12567 C GLN G 151 65.706 -60.631 38.484 1.00156.35 C +ATOM 12568 O GLN G 151 66.052 -60.191 39.562 1.00120.92 O +ATOM 12569 CB GLN G 151 63.756 -62.167 38.707 1.00169.33 C +ATOM 12570 CG GLN G 151 63.161 -63.510 38.327 1.00159.84 C +ATOM 12571 CD GLN G 151 61.875 -63.803 39.051 1.00169.81 C +ATOM 12572 OE1 GLN G 151 61.067 -62.900 39.267 1.00187.09 O +ATOM 12573 NE2 GLN G 151 61.703 -65.049 39.489 1.00172.17 N +ATOM 12574 N TYR G 152 65.770 -59.920 37.363 1.00135.56 N +ATOM 12575 CA TYR G 152 66.197 -58.536 37.403 1.00106.53 C +ATOM 12576 C TYR G 152 65.368 -57.659 36.499 1.00139.47 C +ATOM 12577 O TYR G 152 64.878 -58.101 35.454 1.00159.19 O +ATOM 12578 CB TYR G 152 67.655 -58.418 37.030 1.00 90.73 C +ATOM 12579 CG TYR G 152 67.926 -57.869 35.633 1.00 88.52 C +ATOM 12580 CD1 TYR G 152 67.610 -58.584 34.486 1.00 69.43 C +ATOM 12581 CD2 TYR G 152 68.649 -56.691 35.473 1.00 98.85 C +ATOM 12582 CE1 TYR G 152 67.955 -58.110 33.228 1.00 71.79 C +ATOM 12583 CE2 TYR G 152 69.062 -56.244 34.209 1.00 77.44 C +ATOM 12584 CZ TYR G 152 68.719 -56.949 33.093 1.00 67.71 C +ATOM 12585 OH TYR G 152 69.139 -56.510 31.843 1.00 67.37 O +ATOM 12586 N GLN G 153 65.192 -56.411 36.915 1.00174.28 N +ATOM 12587 CA GLN G 153 64.577 -55.405 36.061 1.00178.07 C +ATOM 12588 C GLN G 153 65.352 -54.100 36.155 1.00146.43 C +ATOM 12589 O GLN G 153 66.027 -53.844 37.155 1.00135.52 O +ATOM 12590 CB GLN G 153 63.118 -55.189 36.470 1.00195.27 C +ATOM 12591 CG GLN G 153 62.194 -56.398 36.257 1.00212.02 C +ATOM 12592 CD GLN G 153 60.778 -56.134 36.799 1.00225.30 C +ATOM 12593 OE1 GLN G 153 60.574 -55.251 37.644 1.00257.98 O +ATOM 12594 NE2 GLN G 153 59.800 -56.891 36.313 1.00214.94 N +ATOM 12595 N LEU G 154 65.285 -53.297 35.101 1.00118.35 N +ATOM 12596 CA LEU G 154 65.881 -51.981 35.166 1.00121.05 C +ATOM 12597 C LEU G 154 65.077 -50.922 34.420 1.00146.48 C +ATOM 12598 O LEU G 154 64.514 -51.169 33.337 1.00166.49 O +ATOM 12599 CB LEU G 154 67.326 -52.005 34.661 1.00117.30 C +ATOM 12600 CG LEU G 154 67.510 -52.185 33.151 1.00126.46 C +ATOM 12601 CD1 LEU G 154 67.665 -50.852 32.430 1.00110.81 C +ATOM 12602 CD2 LEU G 154 68.711 -53.080 32.894 1.00159.55 C +ATOM 12603 N ASP G 155 65.143 -49.707 34.971 1.00158.62 N +ATOM 12604 CA ASP G 155 64.323 -48.564 34.562 1.00121.04 C +ATOM 12605 C ASP G 155 65.249 -47.437 34.079 1.00 95.14 C +ATOM 12606 O ASP G 155 66.419 -47.395 34.467 1.00125.44 O +ATOM 12607 CB ASP G 155 63.464 -48.101 35.761 1.00126.23 C +ATOM 12608 CG ASP G 155 62.771 -49.261 36.481 1.00136.21 C +ATOM 12609 OD1 ASP G 155 63.436 -49.971 37.262 1.00121.60 O +ATOM 12610 OD2 ASP G 155 61.580 -49.505 36.198 1.00172.73 O +ATOM 12611 N GLN G 156 64.721 -46.497 33.307 1.00 72.77 N +ATOM 12612 CA GLN G 156 65.495 -45.312 32.910 1.00 80.34 C +ATOM 12613 C GLN G 156 64.977 -43.976 33.534 1.00 99.39 C +ATOM 12614 O GLN G 156 63.819 -43.860 33.947 1.00128.18 O +ATOM 12615 CB GLN G 156 65.493 -45.206 31.409 1.00 66.25 C +ATOM 12616 CG GLN G 156 66.480 -44.212 30.843 1.00 70.79 C +ATOM 12617 CD GLN G 156 66.769 -44.468 29.374 1.00 97.83 C +ATOM 12618 OE1 GLN G 156 66.152 -45.347 28.744 1.00123.95 O +ATOM 12619 NE2 GLN G 156 67.729 -43.728 28.817 1.00111.20 N +ATOM 12620 N ILE G 157 65.857 -42.982 33.623 1.00 75.97 N +ATOM 12621 CA ILE G 157 65.503 -41.667 34.110 1.00 64.53 C +ATOM 12622 C ILE G 157 66.430 -40.631 33.456 1.00 55.36 C +ATOM 12623 O ILE G 157 67.592 -40.889 33.230 1.00 44.96 O +ATOM 12624 CB ILE G 157 65.615 -41.593 35.647 1.00 73.72 C +ATOM 12625 CG1 ILE G 157 64.719 -40.466 36.213 1.00102.86 C +ATOM 12626 CG2 ILE G 157 67.051 -41.348 36.067 1.00 69.01 C +ATOM 12627 CD1 ILE G 157 64.617 -40.429 37.736 1.00 79.81 C +ATOM 12628 N ALA G 158 65.887 -39.488 33.071 1.00 73.90 N +ATOM 12629 CA ALA G 158 66.672 -38.519 32.325 1.00100.85 C +ATOM 12630 C ALA G 158 66.389 -37.149 32.845 1.00 78.49 C +ATOM 12631 O ALA G 158 65.286 -36.873 33.333 1.00127.80 O +ATOM 12632 CB ALA G 158 66.398 -38.590 30.805 1.00141.92 C +ATOM 12633 N VAL G 159 67.354 -36.266 32.657 1.00 61.35 N +ATOM 12634 CA VAL G 159 67.277 -34.953 33.244 1.00 76.72 C +ATOM 12635 C VAL G 159 67.870 -33.929 32.291 1.00 66.47 C +ATOM 12636 O VAL G 159 68.966 -34.071 31.808 1.00 58.21 O +ATOM 12637 CB VAL G 159 67.993 -34.893 34.628 1.00 94.77 C +ATOM 12638 CG1 VAL G 159 68.354 -33.459 35.005 1.00 94.85 C +ATOM 12639 CG2 VAL G 159 67.133 -35.520 35.736 1.00 89.36 C +ATOM 12640 N ASN G 160 67.112 -32.868 32.066 1.00 90.10 N +ATOM 12641 CA ASN G 160 67.595 -31.689 31.374 1.00 71.89 C +ATOM 12642 C ASN G 160 68.015 -30.681 32.440 1.00 58.70 C +ATOM 12643 O ASN G 160 67.240 -30.350 33.346 1.00 47.18 O +ATOM 12644 CB ASN G 160 66.476 -31.123 30.468 1.00 66.68 C +ATOM 12645 CG ASN G 160 66.885 -29.843 29.742 1.00 72.05 C +ATOM 12646 OD1 ASN G 160 67.350 -28.883 30.341 1.00113.06 O +ATOM 12647 ND2 ASN G 160 66.582 -29.776 28.466 1.00 95.33 N +ATOM 12648 N LEU G 161 69.217 -30.165 32.308 1.00 60.16 N +ATOM 12649 CA LEU G 161 69.560 -28.873 32.924 1.00 70.19 C +ATOM 12650 C LEU G 161 70.027 -27.832 31.876 1.00 61.58 C +ATOM 12651 O LEU G 161 70.591 -28.198 30.847 1.00 69.47 O +ATOM 12652 CB LEU G 161 70.670 -29.089 33.927 1.00 69.97 C +ATOM 12653 CG LEU G 161 70.310 -29.995 35.097 1.00 76.21 C +ATOM 12654 CD1 LEU G 161 71.556 -30.284 35.899 1.00 97.32 C +ATOM 12655 CD2 LEU G 161 69.269 -29.303 35.945 1.00 91.78 C +ATOM 12656 N ARG G 162 69.784 -26.556 32.125 1.00 42.92 N +ATOM 12657 CA ARG G 162 70.172 -25.566 31.160 1.00 56.38 C +ATOM 12658 C ARG G 162 70.430 -24.197 31.762 1.00 67.31 C +ATOM 12659 O ARG G 162 69.615 -23.668 32.524 1.00 89.78 O +ATOM 12660 CB ARG G 162 69.163 -25.482 30.002 1.00 84.08 C +ATOM 12661 CG ARG G 162 67.735 -25.036 30.333 1.00114.53 C +ATOM 12662 CD ARG G 162 66.990 -24.613 29.061 1.00100.39 C +ATOM 12663 NE ARG G 162 65.693 -23.996 29.322 1.00 91.29 N +ATOM 12664 CZ ARG G 162 64.575 -24.671 29.582 1.00125.92 C +ATOM 12665 NH1 ARG G 162 64.580 -26.006 29.667 1.00155.22 N +ATOM 12666 NH2 ARG G 162 63.441 -24.011 29.784 1.00122.78 N +ATOM 12667 N VAL G 163 71.556 -23.606 31.350 1.00 77.06 N +ATOM 12668 CA VAL G 163 71.986 -22.270 31.797 1.00 83.72 C +ATOM 12669 C VAL G 163 71.413 -21.198 30.920 1.00 85.92 C +ATOM 12670 O VAL G 163 71.617 -21.210 29.710 1.00115.42 O +ATOM 12671 CB VAL G 163 73.499 -22.069 31.697 1.00 75.23 C +ATOM 12672 CG1 VAL G 163 73.866 -20.653 32.136 1.00 55.19 C +ATOM 12673 CG2 VAL G 163 74.209 -23.149 32.518 1.00 95.69 C +ATOM 12674 N VAL G 164 70.685 -20.285 31.551 1.00 73.19 N +ATOM 12675 CA VAL G 164 70.043 -19.205 30.858 1.00 83.17 C +ATOM 12676 C VAL G 164 70.734 -17.943 31.310 1.00 73.21 C +ATOM 12677 O VAL G 164 70.870 -17.710 32.498 1.00 42.36 O +ATOM 12678 CB VAL G 164 68.535 -19.117 31.185 1.00129.82 C +ATOM 12679 CG1 VAL G 164 67.896 -17.921 30.482 1.00143.21 C +ATOM 12680 CG2 VAL G 164 67.826 -20.399 30.766 1.00153.24 C +ATOM 12681 N ASN G 165 71.020 -17.080 30.339 1.00 75.67 N +ATOM 12682 CA ASN G 165 71.558 -15.771 30.621 1.00 68.16 C +ATOM 12683 C ASN G 165 70.482 -14.754 30.959 1.00 90.27 C +ATOM 12684 O ASN G 165 69.611 -14.447 30.123 1.00129.51 O +ATOM 12685 CB ASN G 165 72.334 -15.251 29.440 1.00 73.72 C +ATOM 12686 CG ASN G 165 73.069 -13.986 29.776 1.00109.40 C +ATOM 12687 OD1 ASN G 165 73.262 -13.669 30.958 1.00139.75 O +ATOM 12688 ND2 ASN G 165 73.617 -13.340 28.758 1.00152.08 N +ATOM 12689 N VAL G 166 70.536 -14.237 32.184 1.00 97.44 N +ATOM 12690 CA VAL G 166 69.539 -13.301 32.683 1.00 93.80 C +ATOM 12691 C VAL G 166 69.529 -12.075 31.806 1.00 90.71 C +ATOM 12692 O VAL G 166 68.451 -11.530 31.530 1.00158.01 O +ATOM 12693 CB VAL G 166 69.828 -12.895 34.141 1.00119.24 C +ATOM 12694 CG1 VAL G 166 69.237 -11.527 34.493 1.00118.34 C +ATOM 12695 CG2 VAL G 166 69.343 -13.988 35.090 1.00129.45 C +ATOM 12696 N SER G 167 70.704 -11.672 31.334 1.00 66.18 N +ATOM 12697 CA SER G 167 70.837 -10.404 30.667 1.00 75.45 C +ATOM 12698 C SER G 167 70.265 -10.421 29.250 1.00 66.57 C +ATOM 12699 O SER G 167 70.023 -9.347 28.658 1.00 63.35 O +ATOM 12700 CB SER G 167 72.302 -9.998 30.633 1.00103.62 C +ATOM 12701 OG SER G 167 72.903 -10.171 31.910 1.00116.37 O +ATOM 12702 N THR G 168 70.000 -11.613 28.718 1.00 63.77 N +ATOM 12703 CA THR G 168 69.426 -11.730 27.351 1.00 85.20 C +ATOM 12704 C THR G 168 68.279 -12.752 27.159 1.00 80.19 C +ATOM 12705 O THR G 168 67.355 -12.552 26.353 1.00 82.43 O +ATOM 12706 CB THR G 168 70.511 -12.145 26.380 1.00 90.96 C +ATOM 12707 OG1 THR G 168 71.165 -13.302 26.906 1.00 63.02 O +ATOM 12708 CG2 THR G 168 71.509 -11.003 26.193 1.00113.53 C +ATOM 12709 N GLY G 169 68.302 -13.815 27.942 1.00 62.75 N +ATOM 12710 CA GLY G 169 67.327 -14.842 27.779 1.00 63.04 C +ATOM 12711 C GLY G 169 67.910 -15.916 26.898 1.00 98.01 C +ATOM 12712 O GLY G 169 67.300 -16.972 26.723 1.00156.74 O +ATOM 12713 N GLU G 170 69.034 -15.623 26.236 1.00106.97 N +ATOM 12714 CA GLU G 170 69.764 -16.660 25.490 1.00108.58 C +ATOM 12715 C GLU G 170 69.998 -17.801 26.459 1.00 89.60 C +ATOM 12716 O GLU G 170 70.521 -17.603 27.550 1.00109.76 O +ATOM 12717 CB GLU G 170 71.108 -16.136 24.935 1.00103.69 C +ATOM 12718 CG GLU G 170 70.969 -15.282 23.683 1.00 87.93 C +ATOM 12719 CD GLU G 170 71.926 -14.108 23.624 1.00 89.43 C +ATOM 12720 OE1 GLU G 170 72.623 -13.832 24.639 1.00111.23 O +ATOM 12721 OE2 GLU G 170 71.982 -13.444 22.560 1.00 85.51 O +ATOM 12722 N ILE G 171 69.644 -19.001 26.058 1.00 69.82 N +ATOM 12723 CA ILE G 171 70.157 -20.146 26.738 1.00 87.88 C +ATOM 12724 C ILE G 171 71.656 -20.292 26.420 1.00 82.32 C +ATOM 12725 O ILE G 171 72.031 -20.344 25.260 1.00 67.74 O +ATOM 12726 CB ILE G 171 69.381 -21.395 26.319 1.00101.89 C +ATOM 12727 CG1 ILE G 171 67.963 -21.323 26.877 1.00 92.74 C +ATOM 12728 CG2 ILE G 171 70.102 -22.647 26.808 1.00113.06 C +ATOM 12729 CD1 ILE G 171 67.019 -22.284 26.209 1.00 95.38 C +ATOM 12730 N LEU G 172 72.498 -20.381 27.452 1.00101.25 N +ATOM 12731 CA LEU G 172 73.942 -20.471 27.249 1.00118.19 C +ATOM 12732 C LEU G 172 74.454 -21.921 27.231 1.00150.45 C +ATOM 12733 O LEU G 172 75.600 -22.210 26.828 1.00165.21 O +ATOM 12734 CB LEU G 172 74.710 -19.683 28.316 1.00108.12 C +ATOM 12735 CG LEU G 172 75.019 -18.199 28.082 1.00117.43 C +ATOM 12736 CD1 LEU G 172 73.977 -17.630 27.144 1.00 96.06 C +ATOM 12737 CD2 LEU G 172 75.228 -17.331 29.321 1.00134.56 C +ATOM 12738 N SER G 173 73.602 -22.842 27.662 1.00156.59 N +ATOM 12739 CA SER G 173 73.949 -24.265 27.628 1.00148.20 C +ATOM 12740 C SER G 173 72.767 -25.155 27.949 1.00119.26 C +ATOM 12741 O SER G 173 72.033 -24.892 28.912 1.00164.41 O +ATOM 12742 CB SER G 173 75.030 -24.551 28.660 1.00190.05 C +ATOM 12743 OG SER G 173 75.133 -25.940 28.908 1.00176.86 O +ATOM 12744 N SER G 174 72.574 -26.204 27.159 1.00 79.37 N +ATOM 12745 CA SER G 174 71.566 -27.219 27.501 1.00 99.01 C +ATOM 12746 C SER G 174 72.248 -28.545 27.547 1.00111.47 C +ATOM 12747 O SER G 174 73.059 -28.858 26.664 1.00162.70 O +ATOM 12748 CB SER G 174 70.405 -27.267 26.473 1.00107.68 C +ATOM 12749 OG SER G 174 69.323 -28.098 26.905 1.00 72.21 O +ATOM 12750 N VAL G 175 71.902 -29.348 28.545 1.00103.99 N +ATOM 12751 CA VAL G 175 72.491 -30.683 28.686 1.00110.67 C +ATOM 12752 C VAL G 175 71.454 -31.721 29.085 1.00116.23 C +ATOM 12753 O VAL G 175 70.542 -31.441 29.851 1.00141.33 O +ATOM 12754 CB VAL G 175 73.642 -30.711 29.723 1.00112.24 C +ATOM 12755 CG1 VAL G 175 74.787 -29.819 29.271 1.00125.50 C +ATOM 12756 CG2 VAL G 175 73.168 -30.264 31.088 1.00113.51 C +ATOM 12757 N ASN G 176 71.638 -32.938 28.589 1.00129.64 N +ATOM 12758 CA ASN G 176 70.655 -34.004 28.736 1.00157.80 C +ATOM 12759 C ASN G 176 71.317 -35.281 29.304 1.00111.57 C +ATOM 12760 O ASN G 176 71.746 -36.126 28.539 1.00115.65 O +ATOM 12761 CB ASN G 176 70.031 -34.292 27.341 1.00169.52 C +ATOM 12762 CG ASN G 176 68.714 -33.548 27.083 1.00142.38 C +ATOM 12763 OD1 ASN G 176 67.912 -33.899 26.167 1.00 88.98 O +ATOM 12764 ND2 ASN G 176 68.413 -32.608 27.966 1.00170.85 N +ATOM 12765 N THR G 177 71.241 -35.485 30.613 1.00 92.85 N +ATOM 12766 CA THR G 177 71.802 -36.676 31.246 1.00100.30 C +ATOM 12767 C THR G 177 70.771 -37.786 31.500 1.00113.41 C +ATOM 12768 O THR G 177 69.568 -37.531 31.500 1.00154.91 O +ATOM 12769 CB THR G 177 72.466 -36.321 32.582 1.00123.04 C +ATOM 12770 OG1 THR G 177 71.468 -35.986 33.552 1.00126.17 O +ATOM 12771 CG2 THR G 177 73.417 -35.128 32.414 1.00142.66 C +ATOM 12772 N SER G 178 71.255 -39.014 31.707 1.00135.89 N +ATOM 12773 CA SER G 178 70.397 -40.207 31.848 1.00126.60 C +ATOM 12774 C SER G 178 71.034 -41.258 32.754 1.00 98.92 C +ATOM 12775 O SER G 178 72.244 -41.309 32.914 1.00135.70 O +ATOM 12776 CB SER G 178 70.113 -40.861 30.488 1.00110.10 C +ATOM 12777 OG SER G 178 69.550 -42.154 30.662 1.00 99.13 O +ATOM 12778 N LYS G 179 70.206 -42.084 33.367 1.00 89.39 N +ATOM 12779 CA LYS G 179 70.676 -42.980 34.407 1.00101.78 C +ATOM 12780 C LYS G 179 69.719 -44.141 34.568 1.00121.11 C +ATOM 12781 O LYS G 179 68.489 -43.996 34.443 1.00209.75 O +ATOM 12782 CB LYS G 179 70.817 -42.220 35.732 1.00126.65 C +ATOM 12783 CG LYS G 179 71.991 -42.669 36.586 1.00133.90 C +ATOM 12784 CD LYS G 179 71.547 -43.708 37.596 1.00116.17 C +ATOM 12785 CE LYS G 179 72.749 -44.271 38.321 1.00125.57 C +ATOM 12786 NZ LYS G 179 72.388 -45.486 39.087 1.00127.32 N +ATOM 12787 N THR G 180 70.281 -45.297 34.855 1.00102.92 N +ATOM 12788 CA THR G 180 69.505 -46.517 34.925 1.00127.75 C +ATOM 12789 C THR G 180 69.339 -46.985 36.382 1.00131.21 C +ATOM 12790 O THR G 180 70.305 -47.044 37.158 1.00166.89 O +ATOM 12791 CB THR G 180 70.120 -47.637 34.058 1.00155.89 C +ATOM 12792 OG1 THR G 180 69.729 -48.922 34.566 1.00185.94 O +ATOM 12793 CG2 THR G 180 71.642 -47.546 34.048 1.00193.20 C +ATOM 12794 N ILE G 181 68.111 -47.355 36.733 1.00132.72 N +ATOM 12795 CA ILE G 181 67.801 -47.867 38.076 1.00158.71 C +ATOM 12796 C ILE G 181 67.699 -49.402 38.081 1.00173.11 C +ATOM 12797 O ILE G 181 66.846 -49.972 37.405 1.00187.67 O +ATOM 12798 CB ILE G 181 66.485 -47.255 38.618 1.00161.62 C +ATOM 12799 CG1 ILE G 181 66.523 -45.728 38.514 1.00180.36 C +ATOM 12800 CG2 ILE G 181 66.232 -47.656 40.066 1.00124.29 C +ATOM 12801 CD1 ILE G 181 65.440 -45.149 37.627 1.00196.09 C +ATOM 12802 N LEU G 182 68.581 -50.050 38.845 1.00186.77 N +ATOM 12803 CA LEU G 182 68.668 -51.515 38.908 1.00175.30 C +ATOM 12804 C LEU G 182 67.840 -52.138 40.038 1.00147.24 C +ATOM 12805 O LEU G 182 67.851 -51.661 41.175 1.00 98.43 O +ATOM 12806 CB LEU G 182 70.130 -51.944 39.071 1.00172.88 C +ATOM 12807 CG LEU G 182 70.370 -53.452 39.167 1.00171.50 C +ATOM 12808 CD1 LEU G 182 69.934 -54.201 37.912 1.00136.41 C +ATOM 12809 CD2 LEU G 182 71.840 -53.678 39.471 1.00199.84 C +ATOM 12810 N SER G 183 67.203 -53.260 39.721 1.00146.50 N +ATOM 12811 CA SER G 183 66.490 -54.056 40.710 1.00152.06 C +ATOM 12812 C SER G 183 66.722 -55.546 40.460 1.00140.84 C +ATOM 12813 O SER G 183 66.760 -55.983 39.303 1.00150.63 O +ATOM 12814 CB SER G 183 64.991 -53.746 40.640 1.00197.87 C +ATOM 12815 OG SER G 183 64.759 -52.367 40.391 1.00238.70 O +ATOM 12816 N TYR G 184 66.860 -56.326 41.533 1.00135.97 N +ATOM 12817 CA TYR G 184 67.034 -57.787 41.410 1.00136.65 C +ATOM 12818 C TYR G 184 66.573 -58.604 42.631 1.00112.24 C +ATOM 12819 O TYR G 184 66.466 -58.090 43.750 1.00 81.52 O +ATOM 12820 CB TYR G 184 68.486 -58.164 41.063 1.00120.06 C +ATOM 12821 CG TYR G 184 69.510 -57.733 42.074 1.00113.22 C +ATOM 12822 CD1 TYR G 184 69.713 -58.458 43.251 1.00111.23 C +ATOM 12823 CD2 TYR G 184 70.242 -56.570 41.883 1.00111.03 C +ATOM 12824 CE1 TYR G 184 70.641 -58.056 44.193 1.00134.92 C +ATOM 12825 CE2 TYR G 184 71.135 -56.134 42.841 1.00123.54 C +ATOM 12826 CZ TYR G 184 71.347 -56.888 43.982 1.00145.25 C +ATOM 12827 OH TYR G 184 72.219 -56.430 44.952 1.00172.01 O +ATOM 12828 N GLU G 185 66.203 -59.850 42.344 1.00115.42 N +ATOM 12829 CA GLU G 185 65.599 -60.749 43.328 1.00126.94 C +ATOM 12830 C GLU G 185 66.242 -62.102 43.239 1.00142.76 C +ATOM 12831 O GLU G 185 66.081 -62.813 42.246 1.00159.80 O +ATOM 12832 CB GLU G 185 64.085 -60.946 43.136 1.00157.24 C +ATOM 12833 CG GLU G 185 63.268 -59.707 42.826 1.00174.38 C +ATOM 12834 CD GLU G 185 61.774 -59.992 42.880 1.00163.21 C +ATOM 12835 OE1 GLU G 185 61.392 -61.163 43.108 1.00142.71 O +ATOM 12836 OE2 GLU G 185 60.982 -59.043 42.707 1.00179.39 O +ATOM 12837 N VAL G 186 66.983 -62.446 44.277 1.00158.50 N +ATOM 12838 CA VAL G 186 67.650 -63.730 44.368 1.00161.90 C +ATOM 12839 C VAL G 186 66.887 -64.625 45.324 1.00149.09 C +ATOM 12840 O VAL G 186 66.378 -64.180 46.353 1.00121.74 O +ATOM 12841 CB VAL G 186 69.092 -63.577 44.874 1.00178.48 C +ATOM 12842 CG1 VAL G 186 69.827 -64.905 44.783 1.00214.03 C +ATOM 12843 CG2 VAL G 186 69.829 -62.510 44.080 1.00178.19 C +ATOM 12844 N GLN G 187 66.767 -65.892 44.963 1.00166.90 N +ATOM 12845 CA GLN G 187 65.930 -66.774 45.732 1.00171.66 C +ATOM 12846 C GLN G 187 66.390 -68.244 45.611 1.00177.64 C +ATOM 12847 O GLN G 187 66.822 -68.699 44.539 1.00163.76 O +ATOM 12848 CB GLN G 187 64.480 -66.538 45.335 1.00155.38 C +ATOM 12849 CG GLN G 187 63.520 -67.476 46.005 1.00133.17 C +ATOM 12850 CD GLN G 187 62.108 -67.281 45.514 1.00136.46 C +ATOM 12851 OE1 GLN G 187 61.892 -66.932 44.358 1.00143.63 O +ATOM 12852 NE2 GLN G 187 61.139 -67.447 46.406 1.00124.87 N +ATOM 12853 N ALA G 188 66.400 -68.946 46.745 1.00161.56 N +ATOM 12854 CA ALA G 188 66.835 -70.344 46.774 1.00135.45 C +ATOM 12855 C ALA G 188 65.985 -71.159 47.744 1.00131.09 C +ATOM 12856 O ALA G 188 65.598 -70.670 48.792 1.00 96.98 O +ATOM 12857 CB ALA G 188 68.303 -70.436 47.161 1.00144.57 C +ATOM 12858 N GLY G 189 65.677 -72.394 47.371 1.00152.21 N +ATOM 12859 CA GLY G 189 64.884 -73.276 48.214 1.00161.19 C +ATOM 12860 C GLY G 189 65.319 -74.729 48.106 1.00198.39 C +ATOM 12861 O GLY G 189 65.597 -75.230 47.013 1.00172.06 O +ATOM 12862 N VAL G 190 65.347 -75.416 49.243 1.00212.43 N +ATOM 12863 CA VAL G 190 65.653 -76.848 49.282 1.00196.50 C +ATOM 12864 C VAL G 190 64.435 -77.642 49.764 1.00177.90 C +ATOM 12865 O VAL G 190 63.740 -77.221 50.691 1.00113.41 O +ATOM 12866 CB VAL G 190 66.842 -77.132 50.213 1.00191.90 C +ATOM 12867 CG1 VAL G 190 67.307 -78.566 50.047 1.00180.69 C +ATOM 12868 CG2 VAL G 190 67.982 -76.149 49.947 1.00181.40 C +ATOM 12869 N PHE G 191 64.136 -78.745 49.082 1.00196.62 N +ATOM 12870 CA PHE G 191 62.870 -79.455 49.285 1.00220.44 C +ATOM 12871 C PHE G 191 63.124 -80.952 49.418 1.00211.98 C +ATOM 12872 O PHE G 191 63.822 -81.535 48.584 1.00217.48 O +ATOM 12873 CB PHE G 191 61.896 -79.167 48.122 1.00220.40 C +ATOM 12874 CG PHE G 191 60.450 -79.408 48.456 1.00197.94 C +ATOM 12875 CD1 PHE G 191 59.962 -80.698 48.592 1.00175.36 C +ATOM 12876 CD2 PHE G 191 59.568 -78.342 48.607 1.00195.21 C +ATOM 12877 CE1 PHE G 191 58.629 -80.924 48.886 1.00180.16 C +ATOM 12878 CE2 PHE G 191 58.236 -78.562 48.912 1.00199.02 C +ATOM 12879 CZ PHE G 191 57.762 -79.856 49.041 1.00185.16 C +ATOM 12880 N LEU G 200 61.103 -82.121 54.574 1.00155.94 N +ATOM 12881 CA LEU G 200 62.037 -81.000 54.670 1.00204.34 C +ATOM 12882 C LEU G 200 61.812 -79.986 53.558 1.00210.57 C +ATOM 12883 O LEU G 200 62.061 -80.277 52.385 1.00153.96 O +ATOM 12884 CB LEU G 200 63.494 -81.480 54.608 1.00215.86 C +ATOM 12885 CG LEU G 200 64.540 -80.350 54.496 1.00200.18 C +ATOM 12886 CD1 LEU G 200 65.173 -80.090 55.858 1.00189.10 C +ATOM 12887 CD2 LEU G 200 65.604 -80.615 53.430 1.00161.00 C +ATOM 12888 N GLU G 201 61.380 -78.785 53.945 1.00210.54 N +ATOM 12889 CA GLU G 201 61.505 -77.605 53.095 1.00183.94 C +ATOM 12890 C GLU G 201 62.349 -76.532 53.781 1.00162.92 C +ATOM 12891 O GLU G 201 62.331 -76.412 55.002 1.00110.15 O +ATOM 12892 CB GLU G 201 60.128 -77.036 52.745 1.00166.77 C +ATOM 12893 CG GLU G 201 60.152 -76.144 51.508 1.00153.96 C +ATOM 12894 CD GLU G 201 58.795 -75.578 51.135 1.00157.97 C +ATOM 12895 OE1 GLU G 201 57.817 -76.355 51.061 1.00187.73 O +ATOM 12896 OE2 GLU G 201 58.702 -74.345 50.937 1.00141.32 O +ATOM 12897 N GLY G 202 63.086 -75.758 52.987 1.00157.19 N +ATOM 12898 CA GLY G 202 63.825 -74.601 53.490 1.00150.20 C +ATOM 12899 C GLY G 202 63.997 -73.563 52.384 1.00152.38 C +ATOM 12900 O GLY G 202 64.542 -73.884 51.321 1.00108.78 O +ATOM 12901 N GLU G 203 63.613 -72.318 52.661 1.00156.85 N +ATOM 12902 CA GLU G 203 63.671 -71.265 51.629 1.00150.71 C +ATOM 12903 C GLU G 203 64.337 -69.968 52.106 1.00130.79 C +ATOM 12904 O GLU G 203 64.042 -69.449 53.181 1.00 77.43 O +ATOM 12905 CB GLU G 203 62.300 -70.850 51.067 1.00162.39 C +ATOM 12906 CG GLU G 203 61.270 -70.429 52.110 1.00172.21 C +ATOM 12907 CD GLU G 203 59.965 -69.865 51.520 1.00165.92 C +ATOM 12908 OE1 GLU G 203 59.909 -69.592 50.303 1.00171.01 O +ATOM 12909 OE2 GLU G 203 58.986 -69.659 52.285 1.00176.18 O +ATOM 12910 N VAL G 204 65.204 -69.422 51.260 1.00143.29 N +ATOM 12911 CA VAL G 204 65.837 -68.121 51.478 1.00172.48 C +ATOM 12912 C VAL G 204 65.550 -67.223 50.275 1.00178.85 C +ATOM 12913 O VAL G 204 65.647 -67.662 49.125 1.00157.84 O +ATOM 12914 CB VAL G 204 67.367 -68.280 51.694 1.00173.50 C +ATOM 12915 CG1 VAL G 204 68.113 -66.956 51.545 1.00165.32 C +ATOM 12916 CG2 VAL G 204 67.631 -68.888 53.064 1.00155.07 C +ATOM 12917 N GLY G 205 65.225 -65.960 50.550 1.00158.04 N +ATOM 12918 CA GLY G 205 65.040 -64.965 49.501 1.00136.82 C +ATOM 12919 C GLY G 205 65.671 -63.619 49.839 1.00106.70 C +ATOM 12920 O GLY G 205 65.806 -63.260 51.003 1.00 73.71 O +ATOM 12921 N TYR G 206 66.074 -62.881 48.814 1.00108.06 N +ATOM 12922 CA TYR G 206 66.598 -61.524 48.985 1.00126.64 C +ATOM 12923 C TYR G 206 66.220 -60.679 47.784 1.00135.69 C +ATOM 12924 O TYR G 206 66.300 -61.152 46.651 1.00145.18 O +ATOM 12925 CB TYR G 206 68.137 -61.541 49.142 1.00149.92 C +ATOM 12926 CG TYR G 206 68.779 -60.147 49.240 1.00136.94 C +ATOM 12927 CD1 TYR G 206 68.703 -59.393 50.421 1.00 91.19 C +ATOM 12928 CD2 TYR G 206 69.466 -59.599 48.153 1.00139.75 C +ATOM 12929 CE1 TYR G 206 69.282 -58.146 50.521 1.00 65.06 C +ATOM 12930 CE2 TYR G 206 70.058 -58.351 48.244 1.00120.11 C +ATOM 12931 CZ TYR G 206 69.951 -57.628 49.428 1.00 93.33 C +ATOM 12932 OH TYR G 206 70.506 -56.366 49.471 1.00124.60 O +ATOM 12933 N THR G 207 65.903 -59.409 48.015 1.00118.13 N +ATOM 12934 CA THR G 207 65.616 -58.490 46.913 1.00130.03 C +ATOM 12935 C THR G 207 66.271 -57.114 47.130 1.00 93.07 C +ATOM 12936 O THR G 207 66.243 -56.571 48.242 1.00 46.96 O +ATOM 12937 CB THR G 207 64.093 -58.308 46.746 1.00160.93 C +ATOM 12938 OG1 THR G 207 63.547 -57.740 47.941 1.00180.60 O +ATOM 12939 CG2 THR G 207 63.414 -59.639 46.488 1.00170.13 C +ATOM 12940 N SER G 208 66.825 -56.538 46.059 1.00 81.03 N +ATOM 12941 CA SER G 208 67.401 -55.192 46.150 1.00103.90 C +ATOM 12942 C SER G 208 66.962 -54.266 45.018 1.00132.38 C +ATOM 12943 O SER G 208 67.113 -54.594 43.836 1.00103.05 O +ATOM 12944 CB SER G 208 68.924 -55.267 46.185 1.00111.20 C +ATOM 12945 OG SER G 208 69.530 -53.980 46.126 1.00 86.72 O +ATOM 12946 N ASN G 209 66.473 -53.088 45.406 1.00159.89 N +ATOM 12947 CA ASN G 209 66.157 -52.012 44.472 1.00156.21 C +ATOM 12948 C ASN G 209 67.088 -50.835 44.680 1.00141.24 C +ATOM 12949 O ASN G 209 67.348 -50.442 45.816 1.00 94.60 O +ATOM 12950 CB ASN G 209 64.730 -51.517 44.689 1.00143.33 C +ATOM 12951 CG ASN G 209 63.699 -52.524 44.267 1.00146.52 C +ATOM 12952 OD1 ASN G 209 63.366 -52.636 43.087 1.00161.92 O +ATOM 12953 ND2 ASN G 209 63.180 -53.263 45.231 1.00141.96 N +ATOM 12954 N GLU G 210 67.564 -50.258 43.580 1.00133.98 N +ATOM 12955 CA GLU G 210 68.241 -48.978 43.654 1.00116.04 C +ATOM 12956 C GLU G 210 67.208 -47.944 44.049 1.00118.18 C +ATOM 12957 O GLU G 210 66.061 -47.985 43.602 1.00142.74 O +ATOM 12958 CB GLU G 210 68.874 -48.605 42.318 1.00103.15 C +ATOM 12959 CG GLU G 210 70.287 -48.035 42.417 1.00 90.91 C +ATOM 12960 CD GLU G 210 71.026 -48.093 41.080 1.00133.93 C +ATOM 12961 OE1 GLU G 210 70.709 -48.960 40.190 1.00231.30 O +ATOM 12962 OE2 GLU G 210 71.906 -47.230 40.866 1.00 87.74 O +ATOM 12963 N PRO G 211 67.596 -47.017 44.912 1.00113.47 N +ATOM 12964 CA PRO G 211 66.731 -45.880 45.142 1.00131.66 C +ATOM 12965 C PRO G 211 66.653 -44.929 43.922 1.00157.91 C +ATOM 12966 O PRO G 211 67.672 -44.431 43.440 1.00132.42 O +ATOM 12967 CB PRO G 211 67.379 -45.186 46.346 1.00140.68 C +ATOM 12968 CG PRO G 211 68.302 -46.186 46.932 1.00129.00 C +ATOM 12969 CD PRO G 211 68.786 -46.977 45.763 1.00127.86 C +ATOM 12970 N VAL G 212 65.434 -44.665 43.460 1.00163.74 N +ATOM 12971 CA VAL G 212 65.204 -43.741 42.352 1.00137.64 C +ATOM 12972 C VAL G 212 65.713 -42.358 42.779 1.00115.70 C +ATOM 12973 O VAL G 212 66.262 -41.595 42.000 1.00 75.44 O +ATOM 12974 CB VAL G 212 63.687 -43.687 41.972 1.00123.77 C +ATOM 12975 CG1 VAL G 212 63.484 -42.830 40.724 1.00106.07 C +ATOM 12976 CG2 VAL G 212 63.115 -45.086 41.763 1.00114.77 C +ATOM 12977 N MET G 213 65.352 -42.016 44.008 1.00108.59 N +ATOM 12978 CA MET G 213 65.873 -40.876 44.744 1.00 90.84 C +ATOM 12979 C MET G 213 67.334 -40.617 44.413 1.00 79.30 C +ATOM 12980 O MET G 213 67.752 -39.497 44.142 1.00 86.93 O +ATOM 12981 CB MET G 213 65.668 -41.257 46.223 1.00104.98 C +ATOM 12982 CG MET G 213 66.038 -40.267 47.294 1.00110.99 C +ATOM 12983 SD MET G 213 65.659 -41.117 48.883 1.00177.40 S +ATOM 12984 CE MET G 213 67.337 -41.272 49.422 1.00193.36 C +ATOM 12985 N LEU G 214 68.117 -41.676 44.491 1.00105.32 N +ATOM 12986 CA LEU G 214 69.574 -41.575 44.573 1.00128.63 C +ATOM 12987 C LEU G 214 70.096 -41.497 43.161 1.00108.79 C +ATOM 12988 O LEU G 214 71.148 -40.896 42.908 1.00109.86 O +ATOM 12989 CB LEU G 214 70.167 -42.795 45.320 1.00126.36 C +ATOM 12990 CG LEU G 214 71.300 -42.579 46.325 1.00112.08 C +ATOM 12991 CD1 LEU G 214 70.910 -41.618 47.474 1.00115.95 C +ATOM 12992 CD2 LEU G 214 71.756 -43.933 46.874 1.00 98.61 C +ATOM 12993 N CYS G 215 69.323 -42.062 42.243 1.00 79.10 N +ATOM 12994 CA CYS G 215 69.707 -42.038 40.844 1.00105.16 C +ATOM 12995 C CYS G 215 69.458 -40.645 40.291 1.00 86.45 C +ATOM 12996 O CYS G 215 70.229 -40.121 39.437 1.00 76.74 O +ATOM 12997 CB CYS G 215 68.895 -43.069 40.058 1.00124.33 C +ATOM 12998 SG CYS G 215 69.242 -44.769 40.505 1.00126.90 S +ATOM 12999 N LEU G 216 68.344 -40.076 40.725 1.00 69.55 N +ATOM 13000 CA LEU G 216 68.009 -38.732 40.305 1.00103.85 C +ATOM 13001 C LEU G 216 69.127 -37.796 40.747 1.00117.73 C +ATOM 13002 O LEU G 216 69.630 -36.986 39.964 1.00 89.90 O +ATOM 13003 CB LEU G 216 66.672 -38.305 40.916 1.00124.10 C +ATOM 13004 CG LEU G 216 66.238 -36.853 40.609 1.00106.87 C +ATOM 13005 CD1 LEU G 216 66.142 -36.553 39.109 1.00 71.50 C +ATOM 13006 CD2 LEU G 216 64.915 -36.552 41.307 1.00 82.93 C +ATOM 13007 N MET G 217 69.546 -37.955 42.001 1.00147.07 N +ATOM 13008 CA MET G 217 70.575 -37.089 42.575 1.00141.51 C +ATOM 13009 C MET G 217 71.897 -37.212 41.815 1.00115.26 C +ATOM 13010 O MET G 217 72.471 -36.221 41.402 1.00 78.48 O +ATOM 13011 CB MET G 217 70.779 -37.414 44.060 1.00156.94 C +ATOM 13012 CG MET G 217 70.893 -36.176 44.931 1.00174.09 C +ATOM 13013 SD MET G 217 72.416 -35.260 44.628 1.00180.68 S +ATOM 13014 CE MET G 217 72.142 -33.747 45.551 1.00198.15 C +ATOM 13015 N SER G 218 72.304 -38.453 41.558 1.00106.70 N +ATOM 13016 CA SER G 218 73.490 -38.743 40.776 1.00 94.24 C +ATOM 13017 C SER G 218 73.462 -38.036 39.414 1.00104.95 C +ATOM 13018 O SER G 218 74.424 -37.378 39.009 1.00 99.41 O +ATOM 13019 CB SER G 218 73.628 -40.269 40.587 1.00 79.44 C +ATOM 13020 OG SER G 218 74.906 -40.586 40.048 1.00122.41 O +ATOM 13021 N ALA G 219 72.368 -38.224 38.682 1.00115.00 N +ATOM 13022 CA ALA G 219 72.274 -37.724 37.319 1.00110.03 C +ATOM 13023 C ALA G 219 72.328 -36.180 37.309 1.00133.74 C +ATOM 13024 O ALA G 219 72.856 -35.557 36.373 1.00110.87 O +ATOM 13025 CB ALA G 219 71.002 -38.251 36.670 1.00 94.70 C +ATOM 13026 N ILE G 220 71.769 -35.557 38.344 1.00155.42 N +ATOM 13027 CA ILE G 220 71.751 -34.090 38.418 1.00154.65 C +ATOM 13028 C ILE G 220 73.177 -33.587 38.616 1.00133.11 C +ATOM 13029 O ILE G 220 73.578 -32.582 38.039 1.00 84.31 O +ATOM 13030 CB ILE G 220 70.800 -33.583 39.538 1.00147.24 C +ATOM 13031 CG1 ILE G 220 69.343 -33.835 39.132 1.00153.98 C +ATOM 13032 CG2 ILE G 220 71.028 -32.098 39.818 1.00123.01 C +ATOM 13033 CD1 ILE G 220 68.358 -33.756 40.270 1.00154.62 C +ATOM 13034 N GLU G 221 73.929 -34.282 39.465 1.00133.49 N +ATOM 13035 CA GLU G 221 75.319 -33.918 39.714 1.00114.07 C +ATOM 13036 C GLU G 221 76.085 -33.945 38.398 1.00106.17 C +ATOM 13037 O GLU G 221 76.796 -32.994 38.048 1.00 93.00 O +ATOM 13038 CB GLU G 221 75.935 -34.891 40.732 1.00106.94 C +ATOM 13039 CG GLU G 221 75.477 -34.648 42.165 1.00129.95 C +ATOM 13040 CD GLU G 221 75.715 -35.817 43.113 1.00131.55 C +ATOM 13041 OE1 GLU G 221 75.636 -36.995 42.685 1.00 79.66 O +ATOM 13042 OE2 GLU G 221 76.058 -35.534 44.290 1.00158.11 O +ATOM 13043 N THR G 222 75.960 -35.072 37.698 1.00104.40 N +ATOM 13044 CA THR G 222 76.605 -35.289 36.401 1.00101.85 C +ATOM 13045 C THR G 222 76.292 -34.139 35.462 1.00104.18 C +ATOM 13046 O THR G 222 77.188 -33.599 34.798 1.00 81.00 O +ATOM 13047 CB THR G 222 76.102 -36.607 35.764 1.00106.41 C +ATOM 13048 OG1 THR G 222 76.634 -37.740 36.474 1.00 89.20 O +ATOM 13049 CG2 THR G 222 76.454 -36.671 34.263 1.00 93.40 C +ATOM 13050 N GLY G 223 75.010 -33.774 35.409 1.00111.55 N +ATOM 13051 CA GLY G 223 74.571 -32.646 34.597 1.00136.23 C +ATOM 13052 C GLY G 223 75.296 -31.357 34.967 1.00147.15 C +ATOM 13053 O GLY G 223 75.633 -30.547 34.086 1.00104.41 O +ATOM 13054 N VAL G 224 75.500 -31.140 36.271 1.00126.66 N +ATOM 13055 CA VAL G 224 76.121 -29.904 36.741 1.00101.07 C +ATOM 13056 C VAL G 224 77.553 -29.859 36.242 1.00116.70 C +ATOM 13057 O VAL G 224 78.032 -28.821 35.780 1.00 94.34 O +ATOM 13058 CB VAL G 224 76.106 -29.803 38.267 1.00 81.86 C +ATOM 13059 CG1 VAL G 224 76.942 -28.613 38.703 1.00 87.33 C +ATOM 13060 CG2 VAL G 224 74.686 -29.665 38.773 1.00 90.30 C +ATOM 13061 N ILE G 225 78.223 -31.009 36.281 1.00132.79 N +ATOM 13062 CA ILE G 225 79.596 -31.096 35.781 1.00118.19 C +ATOM 13063 C ILE G 225 79.645 -30.747 34.298 1.00108.76 C +ATOM 13064 O ILE G 225 80.433 -29.874 33.912 1.00103.93 O +ATOM 13065 CB ILE G 225 80.227 -32.480 36.017 1.00 97.29 C +ATOM 13066 CG1 ILE G 225 80.434 -32.712 37.517 1.00 97.01 C +ATOM 13067 CG2 ILE G 225 81.570 -32.575 35.308 1.00 87.30 C +ATOM 13068 CD1 ILE G 225 80.631 -34.168 37.881 1.00106.26 C +ATOM 13069 N PHE G 226 78.797 -31.401 33.489 1.00 79.50 N +ATOM 13070 CA PHE G 226 78.759 -31.143 32.043 1.00 81.53 C +ATOM 13071 C PHE G 226 78.490 -29.664 31.758 1.00110.47 C +ATOM 13072 O PHE G 226 78.982 -29.108 30.775 1.00 97.53 O +ATOM 13073 CB PHE G 226 77.715 -32.006 31.346 1.00 67.78 C +ATOM 13074 CG PHE G 226 78.163 -33.415 31.064 1.00 81.95 C +ATOM 13075 CD1 PHE G 226 79.253 -33.665 30.236 1.00100.84 C +ATOM 13076 CD2 PHE G 226 77.451 -34.505 31.567 1.00 95.58 C +ATOM 13077 CE1 PHE G 226 79.674 -34.967 29.974 1.00111.78 C +ATOM 13078 CE2 PHE G 226 77.825 -35.803 31.262 1.00113.43 C +ATOM 13079 CZ PHE G 226 78.949 -36.037 30.475 1.00130.84 C +ATOM 13080 N LEU G 227 77.708 -29.026 32.626 1.00143.28 N +ATOM 13081 CA LEU G 227 77.401 -27.601 32.481 1.00143.99 C +ATOM 13082 C LEU G 227 78.621 -26.745 32.736 1.00131.30 C +ATOM 13083 O LEU G 227 78.897 -25.822 31.979 1.00123.27 O +ATOM 13084 CB LEU G 227 76.283 -27.220 33.446 1.00138.10 C +ATOM 13085 CG LEU G 227 74.856 -27.617 33.022 1.00136.95 C +ATOM 13086 CD1 LEU G 227 73.803 -27.499 34.105 1.00116.46 C +ATOM 13087 CD2 LEU G 227 74.407 -26.832 31.804 1.00136.16 C +ATOM 13088 N ILE G 228 79.374 -27.080 33.780 1.00130.49 N +ATOM 13089 CA ILE G 228 80.577 -26.318 34.131 1.00126.74 C +ATOM 13090 C ILE G 228 81.619 -26.469 33.037 1.00121.69 C +ATOM 13091 O ILE G 228 82.193 -25.484 32.574 1.00 88.37 O +ATOM 13092 CB ILE G 228 81.207 -26.767 35.471 1.00123.38 C +ATOM 13093 CG1 ILE G 228 80.249 -26.510 36.636 1.00125.25 C +ATOM 13094 CG2 ILE G 228 82.497 -26.006 35.728 1.00102.69 C +ATOM 13095 CD1 ILE G 228 80.606 -27.238 37.913 1.00100.27 C +ATOM 13096 N ASN G 229 81.842 -27.711 32.612 1.00142.83 N +ATOM 13097 CA ASN G 229 82.821 -28.006 31.567 1.00163.57 C +ATOM 13098 C ASN G 229 82.458 -27.299 30.258 1.00176.27 C +ATOM 13099 O ASN G 229 83.309 -26.657 29.631 1.00158.90 O +ATOM 13100 CB ASN G 229 82.910 -29.520 31.345 1.00153.43 C +ATOM 13101 CG ASN G 229 84.168 -29.938 30.608 1.00165.79 C +ATOM 13102 OD1 ASN G 229 85.158 -29.208 30.567 1.00142.17 O +ATOM 13103 ND2 ASN G 229 84.106 -31.096 29.964 1.00203.22 N +ATOM 13104 N ASP G 230 81.176 -27.356 29.902 1.00184.10 N +ATOM 13105 CA ASP G 230 80.673 -26.674 28.724 1.00184.58 C +ATOM 13106 C ASP G 230 80.911 -25.159 28.837 1.00209.41 C +ATOM 13107 O ASP G 230 81.282 -24.497 27.864 1.00210.78 O +ATOM 13108 CB ASP G 230 79.184 -26.977 28.543 1.00163.58 C +ATOM 13109 CG ASP G 230 78.637 -26.450 27.236 1.00188.01 C +ATOM 13110 OD1 ASP G 230 79.030 -27.011 26.180 1.00103.81 O +ATOM 13111 OD2 ASP G 230 77.878 -25.414 27.267 1.00276.30 O +ATOM 13112 N GLY G 231 80.668 -24.604 30.021 1.00206.41 N +ATOM 13113 CA GLY G 231 80.847 -23.170 30.239 1.00198.12 C +ATOM 13114 C GLY G 231 82.309 -22.760 30.150 1.00175.15 C +ATOM 13115 O GLY G 231 82.629 -21.650 29.699 1.00117.58 O +ATOM 13116 N ILE G 232 83.191 -23.641 30.622 1.00176.43 N +ATOM 13117 CA ILE G 232 84.631 -23.413 30.524 1.00161.47 C +ATOM 13118 C ILE G 232 85.024 -23.298 29.059 1.00155.90 C +ATOM 13119 O ILE G 232 85.707 -22.349 28.671 1.00126.44 O +ATOM 13120 CB ILE G 232 85.436 -24.542 31.207 1.00159.35 C +ATOM 13121 CG1 ILE G 232 85.322 -24.410 32.732 1.00150.38 C +ATOM 13122 CG2 ILE G 232 86.902 -24.516 30.771 1.00178.10 C +ATOM 13123 CD1 ILE G 232 85.701 -25.665 33.489 1.00143.47 C +ATOM 13124 N ASP G 233 84.592 -24.273 28.259 1.00167.52 N +ATOM 13125 CA ASP G 233 84.869 -24.283 26.826 1.00162.92 C +ATOM 13126 C ASP G 233 84.367 -22.994 26.184 1.00151.74 C +ATOM 13127 O ASP G 233 85.083 -22.362 25.401 1.00168.96 O +ATOM 13128 CB ASP G 233 84.205 -25.498 26.149 1.00172.21 C +ATOM 13129 CG ASP G 233 84.794 -26.835 26.606 1.00162.16 C +ATOM 13130 OD1 ASP G 233 85.598 -26.848 27.559 1.00141.17 O +ATOM 13131 OD2 ASP G 233 84.469 -27.870 25.979 1.00147.25 O +ATOM 13132 N ARG G 234 83.126 -22.618 26.488 1.00154.91 N +ATOM 13133 CA ARG G 234 82.459 -21.507 25.791 1.00164.50 C +ATOM 13134 C ARG G 234 82.796 -20.125 26.359 1.00125.17 C +ATOM 13135 O ARG G 234 82.356 -19.104 25.813 1.00 77.50 O +ATOM 13136 CB ARG G 234 80.943 -21.704 25.800 1.00158.79 C +ATOM 13137 CG ARG G 234 80.502 -22.796 24.858 1.00149.29 C +ATOM 13138 CD ARG G 234 79.141 -23.329 25.215 1.00143.11 C +ATOM 13139 NE ARG G 234 78.796 -24.414 24.298 1.00192.47 N +ATOM 13140 CZ ARG G 234 77.702 -24.446 23.534 1.00207.92 C +ATOM 13141 NH1 ARG G 234 76.791 -23.481 23.612 1.00146.56 N +ATOM 13142 NH2 ARG G 234 77.516 -25.477 22.706 1.00248.43 N +ATOM 13143 N GLY G 235 83.624 -20.099 27.399 1.00102.55 N +ATOM 13144 CA GLY G 235 84.140 -18.841 27.922 1.00116.07 C +ATOM 13145 C GLY G 235 83.122 -18.119 28.770 1.00123.65 C +ATOM 13146 O GLY G 235 83.090 -16.885 28.791 1.00106.29 O +ATOM 13147 N LEU G 236 82.264 -18.880 29.451 1.00143.14 N +ATOM 13148 CA LEU G 236 81.378 -18.284 30.466 1.00148.53 C +ATOM 13149 C LEU G 236 82.204 -17.958 31.697 1.00126.20 C +ATOM 13150 O LEU G 236 82.136 -16.851 32.229 1.00139.36 O +ATOM 13151 CB LEU G 236 80.217 -19.220 30.854 1.00144.74 C +ATOM 13152 CG LEU G 236 78.961 -19.222 29.963 1.00129.40 C +ATOM 13153 CD1 LEU G 236 79.193 -20.043 28.702 1.00143.04 C +ATOM 13154 CD2 LEU G 236 77.774 -19.775 30.729 1.00114.83 C +ATOM 13155 N TRP G 237 83.004 -18.922 32.124 1.00114.10 N +ATOM 13156 CA TRP G 237 83.823 -18.761 33.316 1.00152.79 C +ATOM 13157 C TRP G 237 85.207 -19.377 33.097 1.00198.59 C +ATOM 13158 O TRP G 237 85.407 -20.149 32.147 1.00245.96 O +ATOM 13159 CB TRP G 237 83.125 -19.390 34.524 1.00132.47 C +ATOM 13160 CG TRP G 237 82.312 -20.583 34.170 1.00128.80 C +ATOM 13161 CD1 TRP G 237 82.778 -21.793 33.749 1.00149.18 C +ATOM 13162 CD2 TRP G 237 80.888 -20.690 34.194 1.00142.49 C +ATOM 13163 NE1 TRP G 237 81.733 -22.653 33.521 1.00142.86 N +ATOM 13164 CE2 TRP G 237 80.560 -22.007 33.800 1.00142.50 C +ATOM 13165 CE3 TRP G 237 79.856 -19.812 34.533 1.00148.66 C +ATOM 13166 CZ2 TRP G 237 79.242 -22.460 33.719 1.00133.67 C +ATOM 13167 CZ3 TRP G 237 78.546 -20.274 34.468 1.00144.28 C +ATOM 13168 CH2 TRP G 237 78.254 -21.581 34.055 1.00128.12 C +ATOM 13169 N ASP G 238 86.152 -19.037 33.977 1.00189.01 N +ATOM 13170 CA ASP G 238 87.548 -19.427 33.799 1.00152.71 C +ATOM 13171 C ASP G 238 88.145 -20.101 35.029 1.00154.22 C +ATOM 13172 O ASP G 238 87.815 -19.769 36.168 1.00126.74 O +ATOM 13173 CB ASP G 238 88.395 -18.220 33.411 1.00118.63 C +ATOM 13174 CG ASP G 238 87.881 -17.531 32.160 1.00122.59 C +ATOM 13175 OD1 ASP G 238 86.918 -16.753 32.273 1.00 92.03 O +ATOM 13176 OD2 ASP G 238 88.445 -17.745 31.062 1.00165.75 O +ATOM 13177 N LEU G 239 89.057 -21.031 34.767 1.00155.97 N +ATOM 13178 CA LEU G 239 89.710 -21.819 35.796 1.00152.36 C +ATOM 13179 C LEU G 239 90.829 -20.980 36.474 1.00170.47 C +ATOM 13180 O LEU G 239 91.454 -20.091 35.854 1.00173.99 O +ATOM 13181 CB LEU G 239 90.151 -23.190 35.188 1.00138.65 C +ATOM 13182 CG LEU G 239 89.777 -24.420 36.017 1.00126.34 C +ATOM 13183 CD1 LEU G 239 90.227 -25.698 35.336 1.00108.69 C +ATOM 13184 CD2 LEU G 239 90.395 -24.333 37.412 1.00116.86 C +ATOM 13185 N GLN G 240 90.953 -21.132 37.794 1.00154.97 N +ATOM 13186 CA GLN G 240 92.051 -20.506 38.537 1.00152.91 C +ATOM 13187 C GLN G 240 93.385 -20.861 37.884 1.00151.24 C +ATOM 13188 O GLN G 240 94.166 -19.983 37.509 1.00148.44 O +ATOM 13189 CB GLN G 240 92.040 -20.975 40.004 1.00157.09 C +ATOM 13190 CG GLN G 240 93.032 -20.241 40.898 1.00148.08 C +ATOM 13191 CD GLN G 240 92.680 -18.768 41.025 1.00141.77 C +ATOM 13192 OE1 GLN G 240 91.827 -18.392 41.837 1.00184.74 O +ATOM 13193 NE2 GLN G 240 93.323 -17.925 40.216 1.00112.64 N +ATOM 13194 N ASN G 241 93.630 -22.162 37.764 1.00150.54 N +ATOM 13195 CA ASN G 241 94.844 -22.680 37.150 1.00144.10 C +ATOM 13196 C ASN G 241 94.550 -23.187 35.752 1.00151.96 C +ATOM 13197 O ASN G 241 93.907 -24.240 35.586 1.00178.05 O +ATOM 13198 CB ASN G 241 95.405 -23.826 37.993 1.00146.87 C +ATOM 13199 CG ASN G 241 96.563 -23.395 38.862 1.00162.48 C +ATOM 13200 OD1 ASN G 241 97.717 -23.651 38.528 1.00155.73 O +ATOM 13201 ND2 ASN G 241 96.267 -22.706 39.967 1.00178.11 N +ATOM 13202 N LYS G 242 95.060 -22.472 34.753 1.00135.07 N +ATOM 13203 CA LYS G 242 94.880 -22.882 33.365 1.00143.74 C +ATOM 13204 C LYS G 242 95.586 -24.220 33.105 1.00169.66 C +ATOM 13205 O LYS G 242 95.175 -24.999 32.233 1.00132.14 O +ATOM 13206 CB LYS G 242 95.399 -21.799 32.419 1.00135.35 C +ATOM 13207 CG LYS G 242 94.911 -20.400 32.764 1.00132.87 C +ATOM 13208 CD LYS G 242 94.243 -19.724 31.579 1.00149.36 C +ATOM 13209 CE LYS G 242 92.929 -19.076 31.991 1.00164.84 C +ATOM 13210 NZ LYS G 242 92.321 -18.269 30.898 1.00173.16 N +ATOM 13211 N ALA G 243 96.618 -24.484 33.912 1.00202.86 N +ATOM 13212 CA ALA G 243 97.339 -25.759 33.924 1.00190.66 C +ATOM 13213 C ALA G 243 96.429 -26.926 34.315 1.00195.18 C +ATOM 13214 O ALA G 243 96.759 -28.084 34.046 1.00208.32 O +ATOM 13215 CB ALA G 243 98.522 -25.685 34.886 1.00157.47 C +ATOM 13216 N GLU G 244 95.297 -26.624 34.956 1.00165.69 N +ATOM 13217 CA GLU G 244 94.390 -27.669 35.414 1.00142.69 C +ATOM 13218 C GLU G 244 93.294 -27.959 34.401 1.00146.07 C +ATOM 13219 O GLU G 244 92.371 -28.700 34.709 1.00129.17 O +ATOM 13220 CB GLU G 244 93.757 -27.297 36.754 1.00139.01 C +ATOM 13221 CG GLU G 244 94.708 -27.382 37.933 1.00154.81 C +ATOM 13222 CD GLU G 244 94.004 -27.264 39.274 1.00153.20 C +ATOM 13223 OE1 GLU G 244 93.628 -26.140 39.658 1.00136.38 O +ATOM 13224 OE2 GLU G 244 93.822 -28.304 39.944 1.00144.87 O +ATOM 13225 N ARG G 245 93.427 -27.437 33.180 1.00137.12 N +ATOM 13226 CA ARG G 245 92.520 -27.808 32.092 1.00142.17 C +ATOM 13227 C ARG G 245 92.455 -29.315 31.832 1.00159.74 C +ATOM 13228 O ARG G 245 91.390 -29.837 31.505 1.00154.55 O +ATOM 13229 CB ARG G 245 92.878 -27.107 30.790 1.00137.94 C +ATOM 13230 CG ARG G 245 91.828 -27.294 29.691 1.00141.37 C +ATOM 13231 CD ARG G 245 92.137 -26.488 28.413 1.00158.50 C +ATOM 13232 NE ARG G 245 91.399 -25.220 28.366 1.00173.44 N +ATOM 13233 CZ ARG G 245 90.084 -25.111 28.160 1.00171.01 C +ATOM 13234 NH1 ARG G 245 89.337 -26.192 27.997 1.00154.53 N +ATOM 13235 NH2 ARG G 245 89.502 -23.918 28.141 1.00159.07 N +ATOM 13236 N GLN G 246 93.591 -30.003 31.944 1.00166.93 N +ATOM 13237 CA GLN G 246 93.642 -31.435 31.636 1.00151.12 C +ATOM 13238 C GLN G 246 93.397 -32.288 32.875 1.00135.48 C +ATOM 13239 O GLN G 246 93.809 -33.445 32.931 1.00156.00 O +ATOM 13240 CB GLN G 246 94.976 -31.807 30.972 1.00153.70 C +ATOM 13241 CG GLN G 246 95.138 -31.297 29.547 1.00152.04 C +ATOM 13242 CD GLN G 246 95.435 -29.814 29.502 1.00166.22 C +ATOM 13243 OE1 GLN G 246 96.281 -29.313 30.255 1.00165.90 O +ATOM 13244 NE2 GLN G 246 94.769 -29.104 28.597 1.00171.38 N +ATOM 13245 N ASN G 247 92.767 -31.690 33.883 1.00128.54 N +ATOM 13246 CA ASN G 247 92.268 -32.418 35.053 1.00154.43 C +ATOM 13247 C ASN G 247 91.603 -33.737 34.648 1.00169.30 C +ATOM 13248 O ASN G 247 90.861 -33.777 33.661 1.00172.15 O +ATOM 13249 CB ASN G 247 91.248 -31.540 35.783 1.00153.87 C +ATOM 13250 CG ASN G 247 91.120 -31.878 37.246 1.00155.64 C +ATOM 13251 OD1 ASN G 247 90.116 -32.454 37.680 1.00165.16 O +ATOM 13252 ND2 ASN G 247 92.142 -31.530 38.015 1.00149.18 N +ATOM 13253 N ASP G 248 91.857 -34.801 35.416 1.00178.38 N +ATOM 13254 CA ASP G 248 91.325 -36.143 35.106 1.00207.99 C +ATOM 13255 C ASP G 248 89.807 -36.118 34.896 1.00231.30 C +ATOM 13256 O ASP G 248 89.273 -36.698 33.937 1.00268.75 O +ATOM 13257 CB ASP G 248 91.635 -37.130 36.243 1.00180.83 C +ATOM 13258 CG ASP G 248 93.101 -37.501 36.325 1.00162.50 C +ATOM 13259 OD1 ASP G 248 93.749 -37.661 35.266 1.00175.11 O +ATOM 13260 OD2 ASP G 248 93.597 -37.660 37.456 1.00128.14 O +ATOM 13261 N ILE G 249 89.122 -35.450 35.818 1.00213.31 N +ATOM 13262 CA ILE G 249 87.671 -35.387 35.809 1.00183.10 C +ATOM 13263 C ILE G 249 87.190 -34.606 34.579 1.00180.30 C +ATOM 13264 O ILE G 249 86.327 -35.072 33.821 1.00216.42 O +ATOM 13265 CB ILE G 249 87.152 -34.730 37.107 1.00144.02 C +ATOM 13266 CG1 ILE G 249 87.539 -35.574 38.324 1.00134.74 C +ATOM 13267 CG2 ILE G 249 85.646 -34.585 37.058 1.00135.39 C +ATOM 13268 CD1 ILE G 249 87.521 -34.817 39.634 1.00136.54 C +ATOM 13269 N LEU G 250 87.768 -33.425 34.374 1.00142.23 N +ATOM 13270 CA LEU G 250 87.372 -32.556 33.266 1.00152.22 C +ATOM 13271 C LEU G 250 87.559 -33.208 31.894 1.00158.93 C +ATOM 13272 O LEU G 250 86.728 -33.022 31.001 1.00176.66 O +ATOM 13273 CB LEU G 250 88.146 -31.240 33.314 1.00153.05 C +ATOM 13274 CG LEU G 250 87.615 -30.213 34.317 1.00166.21 C +ATOM 13275 CD1 LEU G 250 88.596 -29.067 34.515 1.00188.30 C +ATOM 13276 CD2 LEU G 250 86.270 -29.673 33.859 1.00175.26 C +ATOM 13277 N VAL G 251 88.644 -33.964 31.732 1.00164.53 N +ATOM 13278 CA VAL G 251 88.898 -34.669 30.469 1.00153.83 C +ATOM 13279 C VAL G 251 88.017 -35.912 30.325 1.00155.98 C +ATOM 13280 O VAL G 251 87.738 -36.359 29.210 1.00126.16 O +ATOM 13281 CB VAL G 251 90.382 -35.066 30.305 1.00132.09 C +ATOM 13282 CG1 VAL G 251 91.274 -33.841 30.452 1.00112.49 C +ATOM 13283 CG2 VAL G 251 90.778 -36.165 31.288 1.00124.81 C +ATOM 13284 N LYS G 252 87.577 -36.461 31.456 1.00152.60 N +ATOM 13285 CA LYS G 252 86.657 -37.593 31.453 1.00138.30 C +ATOM 13286 C LYS G 252 85.287 -37.167 30.897 1.00159.99 C +ATOM 13287 O LYS G 252 84.722 -37.830 30.013 1.00142.01 O +ATOM 13288 CB LYS G 252 86.541 -38.150 32.876 1.00111.91 C +ATOM 13289 CG LYS G 252 85.588 -39.318 33.039 1.00115.68 C +ATOM 13290 CD LYS G 252 85.547 -39.764 34.496 1.00108.19 C +ATOM 13291 CE LYS G 252 84.119 -39.958 34.982 1.00118.12 C +ATOM 13292 NZ LYS G 252 84.035 -40.140 36.457 1.00119.43 N +ATOM 13293 N TYR G 253 84.785 -36.028 31.375 1.00174.66 N +ATOM 13294 CA TYR G 253 83.477 -35.502 30.938 1.00149.38 C +ATOM 13295 C TYR G 253 83.573 -34.840 29.573 1.00150.83 C +ATOM 13296 O TYR G 253 82.623 -34.885 28.786 1.00166.64 O +ATOM 13297 CB TYR G 253 82.906 -34.528 31.971 1.00118.71 C +ATOM 13298 CG TYR G 253 82.437 -35.250 33.223 1.00136.04 C +ATOM 13299 CD1 TYR G 253 81.183 -35.853 33.281 1.00119.66 C +ATOM 13300 CD2 TYR G 253 83.294 -35.424 34.315 1.00158.59 C +ATOM 13301 CE1 TYR G 253 80.782 -36.546 34.413 1.00110.99 C +ATOM 13302 CE2 TYR G 253 82.895 -36.128 35.449 1.00126.14 C +ATOM 13303 CZ TYR G 253 81.629 -36.668 35.495 1.00104.54 C +ATOM 13304 OH TYR G 253 81.212 -37.329 36.637 1.00103.86 O +ATOM 13305 N ARG G 254 84.735 -34.256 29.285 1.00140.14 N +ATOM 13306 CA ARG G 254 85.048 -33.781 27.933 1.00120.54 C +ATOM 13307 C ARG G 254 84.968 -34.930 26.932 1.00118.09 C +ATOM 13308 O ARG G 254 84.455 -34.768 25.822 1.00 96.90 O +ATOM 13309 CB ARG G 254 86.448 -33.168 27.888 1.00128.89 C +ATOM 13310 CG ARG G 254 86.781 -32.546 26.546 1.00138.56 C +ATOM 13311 CD ARG G 254 87.964 -31.596 26.623 1.00163.62 C +ATOM 13312 NE ARG G 254 87.700 -30.405 27.429 1.00161.82 N +ATOM 13313 CZ ARG G 254 88.227 -30.156 28.624 1.00168.18 C +ATOM 13314 NH1 ARG G 254 89.043 -31.026 29.207 1.00163.68 N +ATOM 13315 NH2 ARG G 254 87.925 -29.024 29.246 1.00167.37 N +ATOM 13316 N HIS G 255 85.454 -36.103 27.352 1.00141.74 N +ATOM 13317 CA HIS G 255 85.444 -37.303 26.508 1.00151.60 C +ATOM 13318 C HIS G 255 84.041 -37.836 26.260 1.00135.16 C +ATOM 13319 O HIS G 255 83.750 -38.351 25.184 1.00109.06 O +ATOM 13320 CB HIS G 255 86.343 -38.405 27.102 1.00167.17 C +ATOM 13321 CG HIS G 255 87.629 -38.592 26.359 1.00183.13 C +ATOM 13322 ND1 HIS G 255 88.675 -37.698 26.451 1.00202.52 N +ATOM 13323 CD2 HIS G 255 88.017 -39.539 25.472 1.00162.88 C +ATOM 13324 CE1 HIS G 255 89.660 -38.098 25.665 1.00196.10 C +ATOM 13325 NE2 HIS G 255 89.286 -39.213 25.062 1.00174.59 N +ATOM 13326 N MET G 256 83.174 -37.732 27.262 1.00148.54 N +ATOM 13327 CA MET G 256 81.803 -38.215 27.104 1.00136.52 C +ATOM 13328 C MET G 256 81.037 -37.379 26.064 1.00137.48 C +ATOM 13329 O MET G 256 80.066 -37.872 25.471 1.00136.21 O +ATOM 13330 CB MET G 256 81.092 -38.268 28.466 1.00137.66 C +ATOM 13331 CG MET G 256 81.862 -39.063 29.526 1.00145.85 C +ATOM 13332 SD MET G 256 80.904 -39.626 30.941 1.00173.89 S +ATOM 13333 CE MET G 256 79.849 -40.857 30.158 1.00170.98 C +ATOM 13334 N SER G 257 81.493 -36.137 25.837 1.00142.61 N +ATOM 13335 CA SER G 257 80.922 -35.235 24.807 1.00122.25 C +ATOM 13336 C SER G 257 81.422 -35.560 23.411 1.00 99.62 C +ATOM 13337 O SER G 257 80.880 -36.461 22.772 1.00119.70 O +ATOM 13338 CB SER G 257 81.246 -33.774 25.122 1.00100.52 C +ATOM 13339 OG SER G 257 81.092 -33.501 26.521 1.00121.49 O +TER 13340 SER G 257 +ATOM 13341 N LEU H 2 74.701 -54.538 56.152 1.00111.27 N +ATOM 13342 CA LEU H 2 73.849 -54.413 54.919 1.00120.07 C +ATOM 13343 C LEU H 2 72.368 -54.189 55.305 1.00134.62 C +ATOM 13344 O LEU H 2 71.495 -55.073 55.131 1.00 94.67 O +ATOM 13345 CB LEU H 2 74.013 -55.633 53.994 1.00122.39 C +ATOM 13346 CG LEU H 2 75.408 -55.936 53.394 1.00115.06 C +ATOM 13347 CD1 LEU H 2 75.326 -57.205 52.549 1.00109.36 C +ATOM 13348 CD2 LEU H 2 76.025 -54.786 52.584 1.00 86.95 C +ATOM 13349 N THR H 3 72.153 -53.048 55.970 1.00177.19 N +ATOM 13350 CA THR H 3 70.832 -52.412 56.118 1.00167.04 C +ATOM 13351 C THR H 3 70.951 -50.882 55.950 1.00120.40 C +ATOM 13352 O THR H 3 69.960 -50.167 55.968 1.00 88.43 O +ATOM 13353 CB THR H 3 70.191 -52.703 57.490 1.00165.82 C +ATOM 13354 OG1 THR H 3 70.927 -52.026 58.518 1.00179.84 O +ATOM 13355 CG2 THR H 3 70.129 -54.217 57.760 1.00151.21 C +ATOM 13356 N ALA H 4 72.178 -50.397 55.805 1.00 98.80 N +ATOM 13357 CA ALA H 4 72.428 -49.133 55.132 1.00112.42 C +ATOM 13358 C ALA H 4 72.230 -49.320 53.606 1.00114.30 C +ATOM 13359 O ALA H 4 71.786 -50.367 53.157 1.00 75.49 O +ATOM 13360 CB ALA H 4 73.832 -48.632 55.451 1.00130.07 C +ATOM 13361 N PRO H 5 72.461 -48.272 52.802 1.00154.99 N +ATOM 13362 CA PRO H 5 71.868 -48.441 51.479 1.00157.27 C +ATOM 13363 C PRO H 5 72.752 -49.279 50.556 1.00158.86 C +ATOM 13364 O PRO H 5 73.900 -49.566 50.895 1.00 83.16 O +ATOM 13365 CB PRO H 5 71.747 -47.002 50.973 1.00172.72 C +ATOM 13366 CG PRO H 5 72.821 -46.229 51.691 1.00185.33 C +ATOM 13367 CD PRO H 5 73.191 -46.994 52.936 1.00172.46 C +ATOM 13368 N PRO H 6 72.222 -49.655 49.384 1.00165.20 N +ATOM 13369 CA PRO H 6 73.049 -50.168 48.283 1.00148.65 C +ATOM 13370 C PRO H 6 73.732 -49.064 47.479 1.00132.21 C +ATOM 13371 O PRO H 6 73.217 -47.958 47.397 1.00141.52 O +ATOM 13372 CB PRO H 6 72.054 -50.934 47.414 1.00155.84 C +ATOM 13373 CG PRO H 6 70.698 -50.449 47.797 1.00156.29 C +ATOM 13374 CD PRO H 6 70.775 -49.766 49.129 1.00142.59 C +ATOM 13375 N LYS H 7 74.891 -49.355 46.900 1.00129.34 N +ATOM 13376 CA LYS H 7 75.616 -48.354 46.090 1.00142.44 C +ATOM 13377 C LYS H 7 75.307 -48.492 44.582 1.00140.17 C +ATOM 13378 O LYS H 7 74.673 -49.468 44.149 1.00115.61 O +ATOM 13379 CB LYS H 7 77.126 -48.424 46.343 1.00138.58 C +ATOM 13380 CG LYS H 7 77.544 -47.727 47.645 1.00136.38 C +ATOM 13381 CD LYS H 7 77.675 -46.276 47.243 1.00133.93 C +ATOM 13382 CE LYS H 7 76.654 -45.365 47.869 1.00142.02 C +ATOM 13383 NZ LYS H 7 77.006 -43.917 47.661 1.00134.30 N +ATOM 13384 N GLU H 8 75.729 -47.485 43.809 1.00129.53 N +ATOM 13385 CA GLU H 8 75.238 -47.279 42.442 1.00154.03 C +ATOM 13386 C GLU H 8 75.685 -48.385 41.492 1.00145.66 C +ATOM 13387 O GLU H 8 76.865 -48.582 41.276 1.00177.47 O +ATOM 13388 CB GLU H 8 75.635 -45.875 41.880 1.00177.46 C +ATOM 13389 CG GLU H 8 77.026 -45.695 41.308 1.00197.90 C +ATOM 13390 CD GLU H 8 77.204 -44.364 40.574 1.00205.77 C +ATOM 13391 OE1 GLU H 8 76.425 -44.070 39.634 1.00188.96 O +ATOM 13392 OE2 GLU H 8 78.151 -43.619 40.916 1.00203.59 O +ATOM 13393 N ALA H 9 74.717 -49.116 40.953 1.00128.59 N +ATOM 13394 CA ALA H 9 74.952 -50.081 39.894 1.00102.25 C +ATOM 13395 C ALA H 9 74.671 -49.433 38.523 1.00102.77 C +ATOM 13396 O ALA H 9 73.523 -49.099 38.207 1.00 95.37 O +ATOM 13397 CB ALA H 9 74.058 -51.287 40.112 1.00 85.42 C +ATOM 13398 N ALA H 10 75.732 -49.244 37.744 1.00 82.19 N +ATOM 13399 CA ALA H 10 75.714 -48.482 36.489 1.00 88.84 C +ATOM 13400 C ALA H 10 75.951 -47.001 36.762 1.00 95.98 C +ATOM 13401 O ALA H 10 75.680 -46.519 37.855 1.00 70.53 O +ATOM 13402 CB ALA H 10 74.438 -48.722 35.666 1.00 67.33 C +ATOM 13403 N ARG H 11 76.458 -46.305 35.740 1.00117.65 N +ATOM 13404 CA ARG H 11 76.868 -44.909 35.886 1.00123.95 C +ATOM 13405 C ARG H 11 75.950 -43.921 35.121 1.00 83.30 C +ATOM 13406 O ARG H 11 75.334 -44.257 34.095 1.00108.49 O +ATOM 13407 CB ARG H 11 78.366 -44.755 35.598 1.00144.22 C +ATOM 13408 CG ARG H 11 79.227 -45.228 36.788 1.00152.60 C +ATOM 13409 CD ARG H 11 80.252 -46.272 36.417 1.00160.74 C +ATOM 13410 NE ARG H 11 80.655 -47.131 37.542 1.00156.14 N +ATOM 13411 CZ ARG H 11 81.358 -48.255 37.407 1.00148.94 C +ATOM 13412 NH1 ARG H 11 81.768 -48.645 36.206 1.00132.44 N +ATOM 13413 NH2 ARG H 11 81.658 -48.990 38.471 1.00140.04 N +ATOM 13414 N PRO H 12 75.811 -42.702 35.636 1.00 56.84 N +ATOM 13415 CA PRO H 12 75.240 -41.673 34.792 1.00 69.87 C +ATOM 13416 C PRO H 12 76.035 -41.415 33.493 1.00 79.36 C +ATOM 13417 O PRO H 12 77.146 -40.908 33.536 1.00 86.04 O +ATOM 13418 CB PRO H 12 75.242 -40.405 35.694 1.00 63.84 C +ATOM 13419 CG PRO H 12 75.589 -40.883 37.048 1.00 64.73 C +ATOM 13420 CD PRO H 12 76.397 -42.130 36.846 1.00 66.88 C +ATOM 13421 N THR H 13 75.416 -41.712 32.355 1.00 97.30 N +ATOM 13422 CA THR H 13 75.861 -41.221 31.057 1.00113.28 C +ATOM 13423 C THR H 13 75.076 -39.975 30.625 1.00106.47 C +ATOM 13424 O THR H 13 73.973 -39.741 31.128 1.00198.84 O +ATOM 13425 CB THR H 13 75.663 -42.322 30.011 1.00134.24 C +ATOM 13426 OG1 THR H 13 76.318 -41.940 28.795 1.00165.30 O +ATOM 13427 CG2 THR H 13 74.141 -42.615 29.754 1.00116.95 C +ATOM 13428 N LEU H 14 75.578 -39.196 29.673 1.00 85.31 N +ATOM 13429 CA LEU H 14 74.694 -38.184 29.057 1.00123.45 C +ATOM 13430 C LEU H 14 73.713 -38.880 28.086 1.00138.03 C +ATOM 13431 O LEU H 14 73.916 -40.032 27.756 1.00129.17 O +ATOM 13432 CB LEU H 14 75.447 -37.022 28.415 1.00114.87 C +ATOM 13433 CG LEU H 14 76.507 -37.351 27.399 1.00122.83 C +ATOM 13434 CD1 LEU H 14 76.576 -36.261 26.346 1.00114.22 C +ATOM 13435 CD2 LEU H 14 77.837 -37.467 28.111 1.00138.63 C +ATOM 13436 N MET H 15 72.578 -38.256 27.766 1.00151.99 N +ATOM 13437 CA MET H 15 71.374 -39.023 27.375 1.00129.96 C +ATOM 13438 C MET H 15 71.560 -39.665 26.000 1.00109.22 C +ATOM 13439 O MET H 15 71.860 -38.974 25.037 1.00 64.96 O +ATOM 13440 CB MET H 15 70.098 -38.152 27.389 1.00125.31 C +ATOM 13441 CG MET H 15 68.819 -38.944 27.676 1.00113.91 C +ATOM 13442 SD MET H 15 67.255 -38.446 26.923 1.00111.27 S +ATOM 13443 CE MET H 15 67.715 -37.512 25.445 1.00102.97 C +ATOM 13444 N PRO H 16 71.407 -41.008 25.930 1.00109.31 N +ATOM 13445 CA PRO H 16 71.727 -41.840 24.755 1.00 98.21 C +ATOM 13446 C PRO H 16 70.922 -41.570 23.487 1.00 82.63 C +ATOM 13447 O PRO H 16 69.926 -42.249 23.198 1.00 87.09 O +ATOM 13448 CB PRO H 16 71.470 -43.268 25.259 1.00112.92 C +ATOM 13449 CG PRO H 16 70.509 -43.109 26.383 1.00112.35 C +ATOM 13450 CD PRO H 16 70.910 -41.834 27.052 1.00106.71 C +ATOM 13451 N ARG H 17 71.295 -40.511 22.789 1.00 90.00 N +ATOM 13452 CA ARG H 17 70.666 -40.181 21.523 1.00123.13 C +ATOM 13453 C ARG H 17 71.385 -40.967 20.425 1.00105.68 C +ATOM 13454 O ARG H 17 72.585 -41.128 20.502 1.00 91.70 O +ATOM 13455 CB ARG H 17 70.723 -38.650 21.289 1.00138.90 C +ATOM 13456 CG ARG H 17 69.544 -37.883 21.892 1.00117.05 C +ATOM 13457 CD ARG H 17 69.807 -36.401 22.028 1.00115.87 C +ATOM 13458 NE ARG H 17 70.641 -36.095 23.180 1.00115.93 N +ATOM 13459 CZ ARG H 17 71.151 -34.889 23.425 1.00127.44 C +ATOM 13460 NH1 ARG H 17 70.888 -33.870 22.602 1.00110.24 N +ATOM 13461 NH2 ARG H 17 71.918 -34.688 24.487 1.00122.61 N +ATOM 13462 N ALA H 18 70.667 -41.374 19.378 1.00117.28 N +ATOM 13463 CA ALA H 18 71.273 -42.138 18.292 1.00103.03 C +ATOM 13464 C ALA H 18 71.305 -41.365 16.957 1.00 94.25 C +ATOM 13465 O ALA H 18 72.011 -40.348 16.836 1.00 75.51 O +ATOM 13466 CB ALA H 18 70.573 -43.475 18.137 1.00 93.45 C +ATOM 13467 N GLN H 19 70.656 -41.913 15.932 1.00 84.97 N +ATOM 13468 CA GLN H 19 71.006 -41.575 14.551 1.00119.18 C +ATOM 13469 C GLN H 19 70.580 -40.144 14.216 1.00118.00 C +ATOM 13470 O GLN H 19 71.352 -39.352 13.634 1.00128.72 O +ATOM 13471 CB GLN H 19 70.352 -42.565 13.574 1.00123.67 C +ATOM 13472 CG GLN H 19 70.744 -42.374 12.108 1.00135.50 C +ATOM 13473 CD GLN H 19 72.245 -42.406 11.882 1.00134.85 C +ATOM 13474 OE1 GLN H 19 72.893 -43.432 12.087 1.00144.40 O +ATOM 13475 NE2 GLN H 19 72.812 -41.266 11.496 1.00141.15 N +ATOM 13476 N SER H 20 69.327 -39.854 14.531 1.00 91.68 N +ATOM 13477 CA SER H 20 68.777 -38.541 14.367 1.00 91.33 C +ATOM 13478 C SER H 20 69.783 -37.498 14.863 1.00109.11 C +ATOM 13479 O SER H 20 70.039 -36.486 14.189 1.00 92.27 O +ATOM 13480 CB SER H 20 67.462 -38.468 15.150 1.00100.46 C +ATOM 13481 OG SER H 20 66.594 -39.536 14.792 1.00 85.88 O +ATOM 13482 N TYR H 21 70.301 -37.714 16.076 1.00133.94 N +ATOM 13483 CA TYR H 21 71.271 -36.791 16.702 1.00148.83 C +ATOM 13484 C TYR H 21 72.515 -36.599 15.836 1.00126.23 C +ATOM 13485 O TYR H 21 72.953 -35.467 15.596 1.00 66.76 O +ATOM 13486 CB TYR H 21 71.683 -37.318 18.085 1.00157.55 C +ATOM 13487 CG TYR H 21 72.664 -36.429 18.824 1.00157.85 C +ATOM 13488 CD1 TYR H 21 72.246 -35.250 19.431 1.00169.91 C +ATOM 13489 CD2 TYR H 21 74.004 -36.760 18.897 1.00176.54 C +ATOM 13490 CE1 TYR H 21 73.131 -34.422 20.087 1.00173.65 C +ATOM 13491 CE2 TYR H 21 74.898 -35.934 19.561 1.00183.72 C +ATOM 13492 CZ TYR H 21 74.449 -34.767 20.158 1.00168.53 C +ATOM 13493 OH TYR H 21 75.320 -33.906 20.782 1.00140.73 O +ATOM 13494 N LYS H 22 73.066 -37.718 15.369 1.00137.09 N +ATOM 13495 CA LYS H 22 74.288 -37.702 14.578 1.00152.00 C +ATOM 13496 C LYS H 22 74.118 -36.914 13.283 1.00168.44 C +ATOM 13497 O LYS H 22 75.011 -36.162 12.879 1.00193.55 O +ATOM 13498 CB LYS H 22 74.730 -39.129 14.259 1.00126.35 C +ATOM 13499 CG LYS H 22 75.631 -39.733 15.311 1.00137.63 C +ATOM 13500 CD LYS H 22 77.082 -39.264 15.100 1.00174.94 C +ATOM 13501 CE LYS H 22 77.908 -40.369 14.429 1.00188.91 C +ATOM 13502 NZ LYS H 22 78.045 -41.560 15.311 1.00201.00 N +ATOM 13503 N ASP H 23 72.965 -37.087 12.644 1.00156.94 N +ATOM 13504 CA ASP H 23 72.609 -36.298 11.463 1.00160.44 C +ATOM 13505 C ASP H 23 72.459 -34.817 11.810 1.00166.05 C +ATOM 13506 O ASP H 23 72.967 -33.946 11.103 1.00144.36 O +ATOM 13507 CB ASP H 23 71.297 -36.807 10.869 1.00158.82 C +ATOM 13508 CG ASP H 23 71.424 -38.183 10.287 1.00162.94 C +ATOM 13509 OD1 ASP H 23 72.451 -38.436 9.627 1.00137.02 O +ATOM 13510 OD2 ASP H 23 70.489 -38.997 10.470 1.00199.45 O +ATOM 13511 N LEU H 24 71.763 -34.554 12.915 1.00165.48 N +ATOM 13512 CA LEU H 24 71.425 -33.193 13.333 1.00152.78 C +ATOM 13513 C LEU H 24 72.667 -32.368 13.667 1.00150.09 C +ATOM 13514 O LEU H 24 72.711 -31.149 13.412 1.00130.55 O +ATOM 13515 CB LEU H 24 70.491 -33.246 14.554 1.00160.78 C +ATOM 13516 CG LEU H 24 69.995 -31.916 15.149 1.00153.56 C +ATOM 13517 CD1 LEU H 24 68.755 -31.418 14.421 1.00172.79 C +ATOM 13518 CD2 LEU H 24 69.710 -32.082 16.630 1.00142.15 C +ATOM 13519 N THR H 25 73.659 -33.023 14.270 1.00152.99 N +ATOM 13520 CA THR H 25 74.882 -32.340 14.688 1.00154.78 C +ATOM 13521 C THR H 25 75.783 -32.008 13.492 1.00148.72 C +ATOM 13522 O THR H 25 76.297 -30.882 13.382 1.00120.98 O +ATOM 13523 CB THR H 25 75.666 -33.179 15.719 1.00148.88 C +ATOM 13524 OG1 THR H 25 75.756 -34.540 15.271 1.00165.03 O +ATOM 13525 CG2 THR H 25 74.977 -33.129 17.073 1.00118.08 C +ATOM 13526 N HIS H 26 75.984 -32.995 12.617 1.00151.52 N +ATOM 13527 CA HIS H 26 76.901 -32.866 11.480 1.00151.68 C +ATOM 13528 C HIS H 26 76.205 -32.192 10.288 1.00124.46 C +ATOM 13529 O HIS H 26 76.432 -32.549 9.133 1.00159.99 O +ATOM 13530 CB HIS H 26 77.475 -34.249 11.089 1.00145.41 C +ATOM 13531 CG HIS H 26 78.341 -34.875 12.146 1.00149.66 C +ATOM 13532 ND1 HIS H 26 77.838 -35.354 13.338 1.00143.01 N +ATOM 13533 CD2 HIS H 26 79.677 -35.100 12.187 1.00165.49 C +ATOM 13534 CE1 HIS H 26 78.826 -35.827 14.077 1.00140.28 C +ATOM 13535 NE2 HIS H 26 79.952 -35.689 13.400 1.00172.79 N +ATOM 13536 N LEU H 27 75.337 -31.232 10.568 1.00 93.91 N +ATOM 13537 CA LEU H 27 74.684 -30.478 9.504 1.00116.86 C +ATOM 13538 C LEU H 27 75.549 -29.282 9.141 1.00101.07 C +ATOM 13539 O LEU H 27 76.019 -28.573 10.027 1.00101.66 O +ATOM 13540 CB LEU H 27 73.275 -30.013 9.935 1.00138.81 C +ATOM 13541 CG LEU H 27 72.135 -31.003 9.666 1.00141.97 C +ATOM 13542 CD1 LEU H 27 70.875 -30.602 10.407 1.00143.46 C +ATOM 13543 CD2 LEU H 27 71.853 -31.120 8.174 1.00146.20 C +ATOM 13544 N PRO H 28 75.701 -29.009 7.836 1.00 98.60 N +ATOM 13545 CA PRO H 28 76.486 -27.860 7.370 1.00112.64 C +ATOM 13546 C PRO H 28 75.944 -26.540 7.879 1.00101.94 C +ATOM 13547 O PRO H 28 74.764 -26.290 7.747 1.00103.64 O +ATOM 13548 CB PRO H 28 76.342 -27.926 5.843 1.00130.19 C +ATOM 13549 CG PRO H 28 75.085 -28.686 5.608 1.00118.95 C +ATOM 13550 CD PRO H 28 75.012 -29.687 6.724 1.00111.20 C +ATOM 13551 N ALA H 29 76.804 -25.709 8.469 1.00127.07 N +ATOM 13552 CA ALA H 29 76.354 -24.527 9.226 1.00121.21 C +ATOM 13553 C ALA H 29 75.848 -23.385 8.307 1.00102.27 C +ATOM 13554 O ALA H 29 76.275 -23.261 7.162 1.00 96.37 O +ATOM 13555 CB ALA H 29 77.464 -24.028 10.149 1.00105.94 C +ATOM 13556 N PRO H 30 74.858 -22.618 8.783 1.00 92.81 N +ATOM 13557 CA PRO H 30 74.292 -21.493 8.043 1.00 95.36 C +ATOM 13558 C PRO H 30 75.206 -20.288 8.124 1.00 87.29 C +ATOM 13559 O PRO H 30 76.198 -20.322 8.869 1.00 64.96 O +ATOM 13560 CB PRO H 30 72.994 -21.203 8.796 1.00125.27 C +ATOM 13561 CG PRO H 30 73.261 -21.652 10.200 1.00130.24 C +ATOM 13562 CD PRO H 30 74.212 -22.807 10.100 1.00112.19 C +ATOM 13563 N THR H 31 74.829 -19.203 7.445 1.00 89.66 N +ATOM 13564 CA THR H 31 75.647 -17.975 7.443 1.00128.91 C +ATOM 13565 C THR H 31 75.683 -17.281 8.810 1.00149.58 C +ATOM 13566 O THR H 31 76.641 -16.579 9.137 1.00171.97 O +ATOM 13567 CB THR H 31 75.202 -16.949 6.361 1.00114.63 C +ATOM 13568 OG1 THR H 31 73.807 -16.669 6.483 1.00115.55 O +ATOM 13569 CG2 THR H 31 75.491 -17.475 4.961 1.00119.74 C +ATOM 13570 N GLY H 32 74.619 -17.454 9.586 1.00155.94 N +ATOM 13571 CA GLY H 32 74.607 -17.059 10.994 1.00155.47 C +ATOM 13572 C GLY H 32 73.540 -17.853 11.713 1.00135.23 C +ATOM 13573 O GLY H 32 72.627 -18.375 11.065 1.00185.89 O +ATOM 13574 N LYS H 33 73.693 -18.049 13.020 1.00110.93 N +ATOM 13575 CA LYS H 33 72.680 -18.796 13.760 1.00102.74 C +ATOM 13576 C LYS H 33 71.385 -17.978 13.837 1.00125.04 C +ATOM 13577 O LYS H 33 71.433 -16.747 13.770 1.00111.83 O +ATOM 13578 CB LYS H 33 73.158 -19.163 15.153 1.00 83.83 C +ATOM 13579 CG LYS H 33 73.842 -20.507 15.250 1.00 76.25 C +ATOM 13580 CD LYS H 33 74.423 -20.720 16.643 1.00 85.47 C +ATOM 13581 CE LYS H 33 75.593 -21.686 16.613 1.00 95.56 C +ATOM 13582 NZ LYS H 33 76.278 -21.784 17.929 1.00 78.63 N +ATOM 13583 N ILE H 34 70.240 -18.664 13.916 1.00132.39 N +ATOM 13584 CA ILE H 34 68.945 -17.994 13.889 1.00130.94 C +ATOM 13585 C ILE H 34 68.367 -18.043 15.305 1.00125.77 C +ATOM 13586 O ILE H 34 68.621 -18.989 16.055 1.00 81.42 O +ATOM 13587 CB ILE H 34 68.008 -18.606 12.810 1.00151.30 C +ATOM 13588 CG1 ILE H 34 68.560 -18.328 11.406 1.00147.22 C +ATOM 13589 CG2 ILE H 34 66.602 -18.020 12.867 1.00166.13 C +ATOM 13590 CD1 ILE H 34 68.908 -19.586 10.639 1.00155.28 C +ATOM 13591 N PHE H 35 67.735 -16.932 15.703 1.00127.29 N +ATOM 13592 CA PHE H 35 67.134 -16.760 17.039 1.00 85.35 C +ATOM 13593 C PHE H 35 65.747 -17.374 17.095 1.00 80.10 C +ATOM 13594 O PHE H 35 64.894 -17.044 16.243 1.00 90.05 O +ATOM 13595 CB PHE H 35 66.974 -15.287 17.317 1.00 67.95 C +ATOM 13596 CG PHE H 35 68.171 -14.644 17.890 1.00 64.39 C +ATOM 13597 CD1 PHE H 35 68.880 -15.252 18.921 1.00 70.85 C +ATOM 13598 CD2 PHE H 35 68.528 -13.372 17.483 1.00 63.89 C +ATOM 13599 CE1 PHE H 35 69.981 -14.630 19.482 1.00 78.24 C +ATOM 13600 CE2 PHE H 35 69.606 -12.730 18.059 1.00 75.29 C +ATOM 13601 CZ PHE H 35 70.342 -13.361 19.052 1.00 83.73 C +ATOM 13602 N VAL H 36 65.519 -18.273 18.045 1.00 54.26 N +ATOM 13603 CA VAL H 36 64.284 -19.020 18.021 1.00 62.27 C +ATOM 13604 C VAL H 36 63.649 -19.092 19.380 1.00 73.81 C +ATOM 13605 O VAL H 36 64.316 -19.031 20.397 1.00 82.81 O +ATOM 13606 CB VAL H 36 64.482 -20.451 17.526 1.00 82.88 C +ATOM 13607 CG1 VAL H 36 65.156 -21.321 18.587 1.00 73.19 C +ATOM 13608 CG2 VAL H 36 63.139 -21.060 17.117 1.00111.22 C +ATOM 13609 N SER H 37 62.322 -19.180 19.398 1.00 88.56 N +ATOM 13610 CA SER H 37 61.580 -19.216 20.650 1.00 76.19 C +ATOM 13611 C SER H 37 60.774 -20.484 20.671 1.00 58.13 C +ATOM 13612 O SER H 37 60.020 -20.739 19.730 1.00 43.92 O +ATOM 13613 CB SER H 37 60.637 -17.997 20.746 1.00 79.96 C +ATOM 13614 OG SER H 37 61.330 -16.787 21.036 1.00 49.46 O +ATOM 13615 N VAL H 38 60.846 -21.223 21.762 1.00 49.80 N +ATOM 13616 CA VAL H 38 59.835 -22.241 21.974 1.00 78.58 C +ATOM 13617 C VAL H 38 59.068 -21.958 23.271 1.00 96.54 C +ATOM 13618 O VAL H 38 59.657 -21.986 24.347 1.00 99.95 O +ATOM 13619 CB VAL H 38 60.450 -23.644 22.066 1.00 87.19 C +ATOM 13620 CG1 VAL H 38 59.380 -24.695 22.338 1.00 84.71 C +ATOM 13621 CG2 VAL H 38 61.209 -23.989 20.793 1.00 89.76 C +ATOM 13622 N TYR H 39 57.738 -21.791 23.162 1.00 94.63 N +ATOM 13623 CA TYR H 39 56.873 -21.540 24.315 1.00 73.30 C +ATOM 13624 C TYR H 39 56.340 -22.860 24.924 1.00 75.05 C +ATOM 13625 O TYR H 39 56.530 -23.128 26.111 1.00 65.26 O +ATOM 13626 CB TYR H 39 55.738 -20.596 23.912 1.00 72.65 C +ATOM 13627 CG TYR H 39 56.138 -19.100 23.958 1.00 66.83 C +ATOM 13628 CD1 TYR H 39 56.856 -18.502 22.922 1.00 40.27 C +ATOM 13629 CD2 TYR H 39 55.742 -18.291 25.043 1.00 74.03 C +ATOM 13630 CE1 TYR H 39 57.141 -17.157 22.941 1.00 30.50 C +ATOM 13631 CE2 TYR H 39 56.077 -16.947 25.101 1.00 53.09 C +ATOM 13632 CZ TYR H 39 56.781 -16.397 24.035 1.00 38.61 C +ATOM 13633 OH TYR H 39 57.150 -15.084 24.172 1.00 40.18 O +ATOM 13634 N ASN H 40 55.756 -23.722 24.099 1.00 73.29 N +ATOM 13635 CA ASN H 40 55.239 -24.997 24.596 1.00 74.00 C +ATOM 13636 C ASN H 40 54.840 -25.990 23.510 1.00 76.26 C +ATOM 13637 O ASN H 40 54.176 -25.634 22.517 1.00 92.92 O +ATOM 13638 CB ASN H 40 54.016 -24.740 25.449 1.00103.84 C +ATOM 13639 CG ASN H 40 53.677 -25.915 26.332 1.00127.31 C +ATOM 13640 OD1 ASN H 40 52.609 -26.520 26.197 1.00150.31 O +ATOM 13641 ND2 ASN H 40 54.578 -26.238 27.251 1.00136.02 N +ATOM 13642 N ILE H 41 55.248 -27.239 23.692 1.00 62.69 N +ATOM 13643 CA ILE H 41 54.784 -28.326 22.843 1.00 71.12 C +ATOM 13644 C ILE H 41 54.009 -29.304 23.719 1.00 71.93 C +ATOM 13645 O ILE H 41 54.600 -29.948 24.590 1.00 68.29 O +ATOM 13646 CB ILE H 41 55.953 -29.053 22.109 1.00 68.15 C +ATOM 13647 CG1 ILE H 41 56.389 -28.281 20.855 1.00 75.00 C +ATOM 13648 CG2 ILE H 41 55.498 -30.417 21.615 1.00 80.81 C +ATOM 13649 CD1 ILE H 41 57.116 -26.987 21.111 1.00 78.30 C +ATOM 13650 N GLN H 42 52.705 -29.461 23.452 1.00 84.61 N +ATOM 13651 CA GLN H 42 51.805 -30.220 24.350 1.00 80.10 C +ATOM 13652 C GLN H 42 51.676 -31.694 24.025 1.00 68.55 C +ATOM 13653 O GLN H 42 52.012 -32.133 22.909 1.00 72.27 O +ATOM 13654 CB GLN H 42 50.401 -29.666 24.314 1.00 83.36 C +ATOM 13655 CG GLN H 42 50.284 -28.250 24.829 1.00 99.11 C +ATOM 13656 CD GLN H 42 49.770 -27.299 23.769 1.00130.40 C +ATOM 13657 OE1 GLN H 42 48.553 -27.156 23.585 1.00176.91 O +ATOM 13658 NE2 GLN H 42 50.687 -26.691 23.013 1.00120.13 N +ATOM 13659 N ASP H 43 51.316 -32.465 25.050 1.00 52.24 N +ATOM 13660 CA ASP H 43 51.059 -33.893 24.883 1.00 63.93 C +ATOM 13661 C ASP H 43 49.663 -34.094 24.352 1.00 58.76 C +ATOM 13662 O ASP H 43 48.792 -34.559 25.091 1.00 49.92 O +ATOM 13663 CB ASP H 43 51.230 -34.633 26.232 1.00 78.31 C +ATOM 13664 CG ASP H 43 51.135 -36.171 26.094 1.00 94.90 C +ATOM 13665 OD1 ASP H 43 51.800 -36.737 25.199 1.00113.74 O +ATOM 13666 OD2 ASP H 43 50.371 -36.819 26.845 1.00 92.90 O +ATOM 13667 N GLU H 44 49.427 -33.649 23.119 1.00 61.27 N +ATOM 13668 CA GLU H 44 48.063 -33.596 22.571 1.00 73.39 C +ATOM 13669 C GLU H 44 47.551 -35.014 22.282 1.00 80.69 C +ATOM 13670 O GLU H 44 46.576 -35.199 21.533 1.00 91.79 O +ATOM 13671 CB GLU H 44 48.014 -32.689 21.306 1.00 87.20 C +ATOM 13672 CG GLU H 44 47.708 -31.199 21.550 1.00103.38 C +ATOM 13673 CD GLU H 44 47.704 -30.320 20.271 1.00126.50 C +ATOM 13674 OE1 GLU H 44 47.126 -30.707 19.213 1.00 99.62 O +ATOM 13675 OE2 GLU H 44 48.250 -29.189 20.327 1.00133.80 O +ATOM 13676 N THR H 45 48.242 -36.012 22.841 1.00 90.84 N +ATOM 13677 CA THR H 45 48.050 -37.422 22.449 1.00106.94 C +ATOM 13678 C THR H 45 46.794 -38.032 23.034 1.00 94.32 C +ATOM 13679 O THR H 45 46.079 -38.755 22.360 1.00126.42 O +ATOM 13680 CB THR H 45 49.270 -38.307 22.786 1.00 91.63 C +ATOM 13681 OG1 THR H 45 49.147 -39.563 22.135 1.00114.49 O +ATOM 13682 CG2 THR H 45 49.407 -38.556 24.273 1.00 78.08 C +ATOM 13683 N GLY H 46 46.516 -37.737 24.291 1.00 93.12 N +ATOM 13684 CA GLY H 46 45.237 -38.122 24.918 1.00100.55 C +ATOM 13685 C GLY H 46 45.302 -39.493 25.571 1.00 90.13 C +ATOM 13686 O GLY H 46 44.272 -40.134 25.874 1.00 91.10 O +ATOM 13687 N GLN H 47 46.503 -39.924 25.886 1.00 76.10 N +ATOM 13688 CA GLN H 47 46.663 -41.304 26.131 1.00 67.24 C +ATOM 13689 C GLN H 47 47.432 -41.585 27.412 1.00 55.24 C +ATOM 13690 O GLN H 47 48.379 -40.879 27.744 1.00 63.29 O +ATOM 13691 CB GLN H 47 47.307 -41.888 24.938 1.00 52.60 C +ATOM 13692 CG GLN H 47 46.413 -41.899 23.723 1.00 60.70 C +ATOM 13693 CD GLN H 47 45.035 -42.484 24.014 1.00 81.45 C +ATOM 13694 OE1 GLN H 47 44.873 -43.686 24.205 1.00 72.06 O +ATOM 13695 NE2 GLN H 47 44.029 -41.640 24.012 1.00137.90 N +ATOM 13696 N PHE H 48 46.917 -42.547 28.164 1.00 45.38 N +ATOM 13697 CA PHE H 48 47.511 -42.992 29.390 1.00 57.85 C +ATOM 13698 C PHE H 48 47.820 -44.478 29.355 1.00 79.01 C +ATOM 13699 O PHE H 48 47.348 -45.208 28.481 1.00128.12 O +ATOM 13700 CB PHE H 48 46.577 -42.726 30.562 1.00 55.10 C +ATOM 13701 CG PHE H 48 46.376 -41.287 30.820 1.00 41.97 C +ATOM 13702 CD1 PHE H 48 45.675 -40.562 29.970 1.00 37.05 C +ATOM 13703 CD2 PHE H 48 47.000 -40.682 31.888 1.00 53.71 C +ATOM 13704 CE1 PHE H 48 45.541 -39.230 30.144 1.00 52.12 C +ATOM 13705 CE2 PHE H 48 46.860 -39.361 32.086 1.00 55.77 C +ATOM 13706 CZ PHE H 48 46.134 -38.626 31.203 1.00 62.08 C +ATOM 13707 N LYS H 49 48.612 -44.918 30.326 1.00 77.96 N +ATOM 13708 CA LYS H 49 49.069 -46.284 30.353 1.00 90.80 C +ATOM 13709 C LYS H 49 47.942 -47.148 30.886 1.00 72.94 C +ATOM 13710 O LYS H 49 47.202 -46.722 31.773 1.00 51.53 O +ATOM 13711 CB LYS H 49 50.375 -46.422 31.194 1.00115.25 C +ATOM 13712 CG LYS H 49 51.565 -45.705 30.550 1.00112.49 C +ATOM 13713 CD LYS H 49 52.928 -45.946 31.167 1.00 99.41 C +ATOM 13714 CE LYS H 49 53.952 -45.284 30.240 1.00115.70 C +ATOM 13715 NZ LYS H 49 55.382 -45.444 30.630 1.00153.74 N +ATOM 13716 N PRO H 50 47.840 -48.384 30.365 1.00 67.76 N +ATOM 13717 CA PRO H 50 46.916 -49.392 30.882 1.00 67.21 C +ATOM 13718 C PRO H 50 47.327 -50.030 32.200 1.00 84.18 C +ATOM 13719 O PRO H 50 48.487 -49.898 32.640 1.00128.90 O +ATOM 13720 CB PRO H 50 46.896 -50.434 29.760 1.00 63.86 C +ATOM 13721 CG PRO H 50 48.233 -50.338 29.129 1.00 59.61 C +ATOM 13722 CD PRO H 50 48.672 -48.908 29.262 1.00 57.81 C +ATOM 13723 N TYR H 51 46.416 -50.782 32.808 1.00 92.99 N +ATOM 13724 CA TYR H 51 46.801 -51.627 33.948 1.00117.31 C +ATOM 13725 C TYR H 51 48.059 -52.442 33.605 1.00122.15 C +ATOM 13726 O TYR H 51 48.120 -53.021 32.513 1.00166.83 O +ATOM 13727 CB TYR H 51 45.666 -52.582 34.341 1.00 98.21 C +ATOM 13728 CG TYR H 51 45.908 -53.188 35.702 1.00 92.10 C +ATOM 13729 CD1 TYR H 51 45.515 -52.514 36.844 1.00 99.62 C +ATOM 13730 CD2 TYR H 51 46.549 -54.414 35.857 1.00104.33 C +ATOM 13731 CE1 TYR H 51 45.747 -53.031 38.107 1.00106.37 C +ATOM 13732 CE2 TYR H 51 46.763 -54.960 37.129 1.00105.88 C +ATOM 13733 CZ TYR H 51 46.386 -54.233 38.248 1.00107.81 C +ATOM 13734 OH TYR H 51 46.551 -54.709 39.529 1.00140.68 O +ATOM 13735 N PRO H 52 49.062 -52.495 34.517 1.00 89.33 N +ATOM 13736 CA PRO H 52 49.043 -52.086 35.919 1.00103.07 C +ATOM 13737 C PRO H 52 49.606 -50.729 36.211 1.00127.72 C +ATOM 13738 O PRO H 52 49.883 -50.438 37.391 1.00170.65 O +ATOM 13739 CB PRO H 52 49.948 -53.115 36.589 1.00111.69 C +ATOM 13740 CG PRO H 52 50.968 -53.412 35.540 1.00110.45 C +ATOM 13741 CD PRO H 52 50.237 -53.330 34.220 1.00 95.68 C +ATOM 13742 N ALA H 53 49.710 -49.876 35.195 1.00115.36 N +ATOM 13743 CA ALA H 53 50.176 -48.524 35.451 1.00129.84 C +ATOM 13744 C ALA H 53 49.212 -47.735 36.356 1.00103.48 C +ATOM 13745 O ALA H 53 48.014 -48.082 36.478 1.00 82.75 O +ATOM 13746 CB ALA H 53 50.394 -47.791 34.145 1.00122.51 C +ATOM 13747 N SER H 54 49.737 -46.688 36.993 1.00 80.49 N +ATOM 13748 CA SER H 54 48.861 -45.730 37.631 1.00 82.71 C +ATOM 13749 C SER H 54 47.927 -45.126 36.587 1.00 84.73 C +ATOM 13750 O SER H 54 48.271 -44.912 35.415 1.00 60.18 O +ATOM 13751 CB SER H 54 49.617 -44.611 38.318 1.00 86.48 C +ATOM 13752 OG SER H 54 48.800 -43.450 38.500 1.00 74.95 O +ATOM 13753 N ASN H 55 46.688 -44.924 37.015 1.00 79.99 N +ATOM 13754 CA ASN H 55 45.670 -44.335 36.168 1.00 71.32 C +ATOM 13755 C ASN H 55 46.179 -43.073 35.497 1.00 69.99 C +ATOM 13756 O ASN H 55 45.750 -42.696 34.376 1.00 59.12 O +ATOM 13757 CB ASN H 55 44.459 -44.019 37.021 1.00 71.95 C +ATOM 13758 CG ASN H 55 43.242 -43.732 36.204 1.00111.40 C +ATOM 13759 OD1 ASN H 55 43.123 -44.120 35.038 1.00171.62 O +ATOM 13760 ND2 ASN H 55 42.286 -43.116 36.839 1.00133.35 N +ATOM 13761 N PHE H 56 47.109 -42.423 36.197 1.00 91.80 N +ATOM 13762 CA PHE H 56 47.545 -41.073 35.849 1.00103.29 C +ATOM 13763 C PHE H 56 48.809 -41.097 35.045 1.00 96.24 C +ATOM 13764 O PHE H 56 49.345 -40.025 34.717 1.00121.08 O +ATOM 13765 CB PHE H 56 47.846 -40.211 37.093 1.00 80.51 C +ATOM 13766 CG PHE H 56 46.686 -40.009 37.991 1.00 59.59 C +ATOM 13767 CD1 PHE H 56 45.533 -39.413 37.554 1.00 48.99 C +ATOM 13768 CD2 PHE H 56 46.739 -40.492 39.263 1.00 70.36 C +ATOM 13769 CE1 PHE H 56 44.433 -39.356 38.370 1.00 59.58 C +ATOM 13770 CE2 PHE H 56 45.665 -40.355 40.121 1.00 76.56 C +ATOM 13771 CZ PHE H 56 44.500 -39.800 39.664 1.00 69.46 C +ATOM 13772 N SER H 57 49.355 -42.273 34.800 1.00 71.27 N +ATOM 13773 CA SER H 57 50.596 -42.305 34.056 1.00 97.29 C +ATOM 13774 C SER H 57 50.298 -42.042 32.571 1.00 61.97 C +ATOM 13775 O SER H 57 49.631 -42.838 31.905 1.00 66.08 O +ATOM 13776 CB SER H 57 51.333 -43.634 34.287 1.00137.35 C +ATOM 13777 OG SER H 57 51.936 -43.657 35.587 1.00103.12 O +ATOM 13778 N THR H 58 50.796 -40.925 32.070 1.00 45.00 N +ATOM 13779 CA THR H 58 50.653 -40.632 30.677 1.00 66.46 C +ATOM 13780 C THR H 58 51.441 -41.585 29.797 1.00 70.58 C +ATOM 13781 O THR H 58 52.484 -42.079 30.142 1.00 61.60 O +ATOM 13782 CB THR H 58 51.141 -39.232 30.382 1.00 78.77 C +ATOM 13783 OG1 THR H 58 52.530 -39.141 30.693 1.00111.16 O +ATOM 13784 CG2 THR H 58 50.408 -38.265 31.249 1.00 90.95 C +ATOM 13785 N ALA H 59 50.983 -41.757 28.588 1.00 99.75 N +ATOM 13786 CA ALA H 59 51.678 -42.683 27.740 1.00 99.22 C +ATOM 13787 C ALA H 59 52.946 -42.060 27.208 1.00 65.78 C +ATOM 13788 O ALA H 59 53.833 -42.772 26.743 1.00 87.63 O +ATOM 13789 CB ALA H 59 50.787 -43.144 26.609 1.00113.23 C +ATOM 13790 N VAL H 60 53.031 -40.749 27.273 1.00 46.02 N +ATOM 13791 CA VAL H 60 54.107 -40.049 26.644 1.00 65.19 C +ATOM 13792 C VAL H 60 54.620 -39.036 27.654 1.00 79.32 C +ATOM 13793 O VAL H 60 53.835 -38.348 28.291 1.00 99.57 O +ATOM 13794 CB VAL H 60 53.612 -39.327 25.352 1.00 70.37 C +ATOM 13795 CG1 VAL H 60 54.726 -38.504 24.670 1.00 57.69 C +ATOM 13796 CG2 VAL H 60 53.025 -40.345 24.372 1.00 62.85 C +ATOM 13797 N PRO H 61 55.938 -38.824 27.691 1.00 87.54 N +ATOM 13798 CA PRO H 61 56.458 -37.817 28.607 1.00109.31 C +ATOM 13799 C PRO H 61 56.057 -36.392 28.232 1.00106.79 C +ATOM 13800 O PRO H 61 55.950 -36.063 27.038 1.00 98.78 O +ATOM 13801 CB PRO H 61 57.979 -37.987 28.498 1.00119.11 C +ATOM 13802 CG PRO H 61 58.197 -38.642 27.181 1.00107.54 C +ATOM 13803 CD PRO H 61 57.014 -39.538 26.992 1.00 99.45 C +ATOM 13804 N GLN H 62 55.858 -35.559 29.253 1.00 81.60 N +ATOM 13805 CA GLN H 62 55.327 -34.216 29.051 1.00 94.41 C +ATOM 13806 C GLN H 62 56.426 -33.230 28.796 1.00 71.83 C +ATOM 13807 O GLN H 62 56.368 -32.106 29.272 1.00109.98 O +ATOM 13808 CB GLN H 62 54.512 -33.769 30.289 1.00126.08 C +ATOM 13809 CG GLN H 62 53.440 -34.752 30.743 1.00123.59 C +ATOM 13810 CD GLN H 62 52.429 -35.042 29.653 1.00108.05 C +ATOM 13811 OE1 GLN H 62 51.544 -34.247 29.388 1.00103.80 O +ATOM 13812 NE2 GLN H 62 52.603 -36.164 28.974 1.00116.94 N +ATOM 13813 N SER H 63 57.451 -33.662 28.102 1.00 59.32 N +ATOM 13814 CA SER H 63 58.736 -32.995 28.184 1.00 83.26 C +ATOM 13815 C SER H 63 59.209 -32.546 26.818 1.00 78.54 C +ATOM 13816 O SER H 63 60.356 -32.132 26.639 1.00 84.63 O +ATOM 13817 CB SER H 63 59.785 -33.926 28.859 1.00125.68 C +ATOM 13818 OG SER H 63 60.026 -35.142 28.161 1.00 92.58 O +ATOM 13819 N ALA H 64 58.324 -32.683 25.852 1.00 83.89 N +ATOM 13820 CA ALA H 64 58.664 -32.464 24.459 1.00109.81 C +ATOM 13821 C ALA H 64 59.292 -31.084 24.208 1.00108.46 C +ATOM 13822 O ALA H 64 60.215 -30.931 23.394 1.00 83.21 O +ATOM 13823 CB ALA H 64 57.411 -32.647 23.618 1.00117.91 C +ATOM 13824 N THR H 65 58.782 -30.087 24.921 1.00114.04 N +ATOM 13825 CA THR H 65 59.220 -28.711 24.772 1.00116.24 C +ATOM 13826 C THR H 65 60.724 -28.601 24.944 1.00127.77 C +ATOM 13827 O THR H 65 61.409 -27.978 24.130 1.00115.76 O +ATOM 13828 CB THR H 65 58.562 -27.844 25.848 1.00118.12 C +ATOM 13829 OG1 THR H 65 57.202 -28.258 26.004 1.00163.37 O +ATOM 13830 CG2 THR H 65 58.626 -26.361 25.468 1.00125.34 C +ATOM 13831 N ALA H 66 61.225 -29.180 26.030 1.00112.59 N +ATOM 13832 CA ALA H 66 62.621 -29.053 26.352 1.00 90.14 C +ATOM 13833 C ALA H 66 63.473 -29.851 25.352 1.00109.07 C +ATOM 13834 O ALA H 66 64.593 -29.437 25.005 1.00166.21 O +ATOM 13835 CB ALA H 66 62.851 -29.514 27.768 1.00 86.72 C +ATOM 13836 N MET H 67 62.940 -30.985 24.885 1.00114.34 N +ATOM 13837 CA MET H 67 63.628 -31.816 23.883 1.00113.42 C +ATOM 13838 C MET H 67 63.777 -31.055 22.566 1.00117.83 C +ATOM 13839 O MET H 67 64.852 -31.057 21.944 1.00105.98 O +ATOM 13840 CB MET H 67 62.862 -33.106 23.609 1.00101.90 C +ATOM 13841 CG MET H 67 62.871 -34.120 24.735 1.00100.35 C +ATOM 13842 SD MET H 67 61.668 -35.435 24.434 1.00111.29 S +ATOM 13843 CE MET H 67 62.030 -36.560 25.790 1.00 94.91 C +ATOM 13844 N LEU H 68 62.720 -30.338 22.187 1.00113.55 N +ATOM 13845 CA LEU H 68 62.780 -29.526 20.983 1.00135.98 C +ATOM 13846 C LEU H 68 63.810 -28.409 21.111 1.00149.55 C +ATOM 13847 O LEU H 68 64.567 -28.161 20.179 1.00118.02 O +ATOM 13848 CB LEU H 68 61.422 -28.906 20.653 1.00147.46 C +ATOM 13849 CG LEU H 68 61.482 -27.873 19.504 1.00138.32 C +ATOM 13850 CD1 LEU H 68 61.856 -28.545 18.193 1.00125.82 C +ATOM 13851 CD2 LEU H 68 60.178 -27.101 19.348 1.00122.24 C +ATOM 13852 N VAL H 69 63.800 -27.698 22.242 1.00138.44 N +ATOM 13853 CA VAL H 69 64.748 -26.597 22.447 1.00113.49 C +ATOM 13854 C VAL H 69 66.166 -27.151 22.349 1.00143.86 C +ATOM 13855 O VAL H 69 67.044 -26.550 21.733 1.00195.43 O +ATOM 13856 CB VAL H 69 64.565 -25.901 23.811 1.00100.18 C +ATOM 13857 CG1 VAL H 69 65.686 -24.905 24.044 1.00100.27 C +ATOM 13858 CG2 VAL H 69 63.231 -25.182 23.898 1.00 99.65 C +ATOM 13859 N THR H 70 66.386 -28.303 22.981 1.00146.91 N +ATOM 13860 CA THR H 70 67.698 -28.945 22.985 1.00112.15 C +ATOM 13861 C THR H 70 68.109 -29.348 21.575 1.00 88.61 C +ATOM 13862 O THR H 70 69.257 -29.095 21.158 1.00 79.16 O +ATOM 13863 CB THR H 70 67.709 -30.168 23.910 1.00100.86 C +ATOM 13864 OG1 THR H 70 67.297 -29.750 25.220 1.00100.86 O +ATOM 13865 CG2 THR H 70 69.112 -30.789 23.981 1.00118.23 C +ATOM 13866 N ALA H 71 67.177 -29.938 20.838 1.00 75.17 N +ATOM 13867 CA ALA H 71 67.455 -30.301 19.455 1.00107.25 C +ATOM 13868 C ALA H 71 67.763 -29.071 18.591 1.00 96.61 C +ATOM 13869 O ALA H 71 68.712 -29.085 17.769 1.00 89.85 O +ATOM 13870 CB ALA H 71 66.289 -31.069 18.864 1.00129.18 C +ATOM 13871 N LEU H 72 67.001 -28.000 18.805 1.00 80.14 N +ATOM 13872 CA LEU H 72 67.248 -26.729 18.098 1.00102.91 C +ATOM 13873 C LEU H 72 68.629 -26.148 18.408 1.00126.59 C +ATOM 13874 O LEU H 72 69.223 -25.458 17.580 1.00101.04 O +ATOM 13875 CB LEU H 72 66.203 -25.680 18.454 1.00 80.53 C +ATOM 13876 CG LEU H 72 64.811 -25.990 17.959 1.00 80.96 C +ATOM 13877 CD1 LEU H 72 63.825 -25.132 18.706 1.00 75.44 C +ATOM 13878 CD2 LEU H 72 64.678 -25.756 16.463 1.00 97.77 C +ATOM 13879 N LYS H 73 69.168 -26.482 19.579 1.00136.53 N +ATOM 13880 CA LYS H 73 70.505 -26.021 19.943 1.00126.15 C +ATOM 13881 C LYS H 73 71.594 -26.914 19.360 1.00112.36 C +ATOM 13882 O LYS H 73 72.584 -26.410 18.833 1.00103.45 O +ATOM 13883 CB LYS H 73 70.674 -25.940 21.463 1.00146.47 C +ATOM 13884 CG LYS H 73 71.923 -25.169 21.905 1.00156.15 C +ATOM 13885 CD LYS H 73 72.059 -25.115 23.431 1.00150.94 C +ATOM 13886 CE LYS H 73 73.514 -25.001 23.872 1.00149.87 C +ATOM 13887 NZ LYS H 73 73.838 -23.705 24.524 1.00143.27 N +ATOM 13888 N ASP H 74 71.437 -28.228 19.511 1.00 95.80 N +ATOM 13889 CA ASP H 74 72.459 -29.178 19.069 1.00100.95 C +ATOM 13890 C ASP H 74 72.737 -29.030 17.579 1.00 93.22 C +ATOM 13891 O ASP H 74 73.836 -29.343 17.115 1.00112.49 O +ATOM 13892 CB ASP H 74 72.042 -30.617 19.398 1.00102.59 C +ATOM 13893 CG ASP H 74 72.058 -30.918 20.903 1.00112.74 C +ATOM 13894 OD1 ASP H 74 72.823 -30.273 21.670 1.00 82.37 O +ATOM 13895 OD2 ASP H 74 71.247 -31.789 21.314 1.00111.07 O +ATOM 13896 N SER H 75 71.724 -28.601 16.825 1.00 98.26 N +ATOM 13897 CA SER H 75 71.821 -28.502 15.362 1.00131.01 C +ATOM 13898 C SER H 75 72.867 -27.478 14.924 1.00132.25 C +ATOM 13899 O SER H 75 73.379 -27.545 13.798 1.00127.34 O +ATOM 13900 CB SER H 75 70.461 -28.137 14.745 1.00142.29 C +ATOM 13901 OG SER H 75 70.254 -26.731 14.751 1.00140.41 O +ATOM 13902 N ARG H 76 73.139 -26.518 15.803 1.00120.28 N +ATOM 13903 CA ARG H 76 74.038 -25.407 15.511 1.00146.79 C +ATOM 13904 C ARG H 76 73.534 -24.581 14.336 1.00146.01 C +ATOM 13905 O ARG H 76 74.314 -24.028 13.567 1.00145.94 O +ATOM 13906 CB ARG H 76 75.453 -25.898 15.240 1.00156.26 C +ATOM 13907 CG ARG H 76 76.092 -26.661 16.396 1.00156.27 C +ATOM 13908 CD ARG H 76 77.510 -27.076 16.033 1.00139.18 C +ATOM 13909 NE ARG H 76 77.522 -28.106 14.996 1.00149.04 N +ATOM 13910 CZ ARG H 76 77.627 -27.880 13.685 1.00167.73 C +ATOM 13911 NH1 ARG H 76 77.735 -26.646 13.194 1.00160.04 N +ATOM 13912 NH2 ARG H 76 77.616 -28.910 12.851 1.00181.17 N +ATOM 13913 N TRP H 77 72.216 -24.432 14.278 1.00147.87 N +ATOM 13914 CA TRP H 77 71.562 -23.483 13.389 1.00139.18 C +ATOM 13915 C TRP H 77 70.832 -22.365 14.172 1.00149.03 C +ATOM 13916 O TRP H 77 70.743 -21.226 13.708 1.00102.13 O +ATOM 13917 CB TRP H 77 70.564 -24.242 12.524 1.00130.96 C +ATOM 13918 CG TRP H 77 71.127 -24.724 11.246 1.00117.71 C +ATOM 13919 CD1 TRP H 77 71.919 -25.814 11.057 1.00108.25 C +ATOM 13920 CD2 TRP H 77 70.875 -24.176 9.952 1.00109.79 C +ATOM 13921 NE1 TRP H 77 72.168 -25.986 9.724 1.00113.75 N +ATOM 13922 CE2 TRP H 77 71.556 -24.974 9.028 1.00108.47 C +ATOM 13923 CE3 TRP H 77 70.130 -23.086 9.484 1.00118.24 C +ATOM 13924 CZ2 TRP H 77 71.541 -24.704 7.664 1.00122.86 C +ATOM 13925 CZ3 TRP H 77 70.117 -22.820 8.126 1.00109.05 C +ATOM 13926 CH2 TRP H 77 70.812 -23.625 7.235 1.00112.19 C +ATOM 13927 N PHE H 78 70.307 -22.720 15.352 1.00148.06 N +ATOM 13928 CA PHE H 78 69.451 -21.841 16.161 1.00 99.82 C +ATOM 13929 C PHE H 78 69.989 -21.579 17.563 1.00 84.34 C +ATOM 13930 O PHE H 78 70.598 -22.447 18.183 1.00 59.19 O +ATOM 13931 CB PHE H 78 68.108 -22.490 16.358 1.00 97.47 C +ATOM 13932 CG PHE H 78 67.439 -22.876 15.087 1.00100.61 C +ATOM 13933 CD1 PHE H 78 66.878 -21.901 14.253 1.00 89.91 C +ATOM 13934 CD2 PHE H 78 67.347 -24.213 14.733 1.00 78.64 C +ATOM 13935 CE1 PHE H 78 66.235 -22.263 13.096 1.00114.57 C +ATOM 13936 CE2 PHE H 78 66.719 -24.580 13.568 1.00101.12 C +ATOM 13937 CZ PHE H 78 66.160 -23.605 12.744 1.00130.01 C +ATOM 13938 N ILE H 79 69.807 -20.342 18.023 1.00102.58 N +ATOM 13939 CA ILE H 79 69.989 -19.963 19.436 1.00 89.78 C +ATOM 13940 C ILE H 79 68.593 -19.950 20.036 1.00 85.79 C +ATOM 13941 O ILE H 79 67.701 -19.293 19.486 1.00 63.43 O +ATOM 13942 CB ILE H 79 70.566 -18.541 19.589 1.00 85.02 C +ATOM 13943 CG1 ILE H 79 71.803 -18.354 18.708 1.00 97.48 C +ATOM 13944 CG2 ILE H 79 70.909 -18.248 21.039 1.00 73.18 C +ATOM 13945 CD1 ILE H 79 72.099 -16.902 18.351 1.00 87.56 C +ATOM 13946 N PRO H 80 68.376 -20.765 21.080 1.00 83.38 N +ATOM 13947 CA PRO H 80 67.069 -20.751 21.654 1.00 69.92 C +ATOM 13948 C PRO H 80 66.985 -19.714 22.742 1.00 74.73 C +ATOM 13949 O PRO H 80 67.899 -19.605 23.542 1.00 57.36 O +ATOM 13950 CB PRO H 80 66.916 -22.159 22.230 1.00 57.63 C +ATOM 13951 CG PRO H 80 67.841 -22.976 21.440 1.00 77.89 C +ATOM 13952 CD PRO H 80 69.025 -22.070 21.284 1.00 97.04 C +ATOM 13953 N LEU H 81 65.934 -18.888 22.679 1.00 77.75 N +ATOM 13954 CA LEU H 81 65.633 -17.926 23.716 1.00 58.93 C +ATOM 13955 C LEU H 81 64.637 -18.498 24.679 1.00 70.37 C +ATOM 13956 O LEU H 81 63.798 -19.346 24.296 1.00 81.24 O +ATOM 13957 CB LEU H 81 65.079 -16.691 23.113 1.00 59.66 C +ATOM 13958 CG LEU H 81 66.001 -16.124 22.035 1.00 94.72 C +ATOM 13959 CD1 LEU H 81 65.330 -14.936 21.398 1.00 88.92 C +ATOM 13960 CD2 LEU H 81 67.334 -15.709 22.632 1.00133.47 C +ATOM 13961 N GLU H 82 64.915 -18.255 25.960 1.00102.13 N +ATOM 13962 CA GLU H 82 64.221 -18.956 27.060 1.00109.93 C +ATOM 13963 C GLU H 82 62.891 -18.305 27.312 1.00 95.65 C +ATOM 13964 O GLU H 82 62.824 -17.155 27.745 1.00 60.38 O +ATOM 13965 CB GLU H 82 65.043 -18.986 28.362 1.00113.53 C +ATOM 13966 CG GLU H 82 64.319 -19.624 29.557 1.00 91.76 C +ATOM 13967 CD GLU H 82 64.125 -21.162 29.461 1.00 82.73 C +ATOM 13968 OE1 GLU H 82 63.695 -21.698 28.424 1.00 74.33 O +ATOM 13969 OE2 GLU H 82 64.411 -21.868 30.446 1.00 54.39 O +ATOM 13970 N ARG H 83 61.845 -19.044 26.934 1.00100.02 N +ATOM 13971 CA ARG H 83 60.472 -18.624 27.151 1.00 72.80 C +ATOM 13972 C ARG H 83 59.682 -19.648 27.973 1.00 64.97 C +ATOM 13973 O ARG H 83 58.684 -19.289 28.589 1.00 56.35 O +ATOM 13974 CB ARG H 83 59.773 -18.344 25.825 1.00 50.65 C +ATOM 13975 CG ARG H 83 60.467 -17.326 24.956 1.00 36.43 C +ATOM 13976 CD ARG H 83 60.416 -15.968 25.504 1.00 29.69 C +ATOM 13977 NE ARG H 83 60.889 -15.105 24.432 1.00 38.66 N +ATOM 13978 CZ ARG H 83 62.060 -14.487 24.426 1.00 71.26 C +ATOM 13979 NH1 ARG H 83 62.943 -14.649 25.432 1.00 88.81 N +ATOM 13980 NH2 ARG H 83 62.389 -13.703 23.386 1.00 84.82 N +ATOM 13981 N GLN H 84 60.139 -20.894 28.051 1.00 70.61 N +ATOM 13982 CA GLN H 84 59.413 -21.870 28.888 1.00110.37 C +ATOM 13983 C GLN H 84 59.346 -21.398 30.340 1.00 97.25 C +ATOM 13984 O GLN H 84 58.308 -21.471 30.974 1.00118.31 O +ATOM 13985 CB GLN H 84 60.001 -23.293 28.810 1.00117.20 C +ATOM 13986 CG GLN H 84 58.974 -24.418 28.979 1.00100.04 C +ATOM 13987 CD GLN H 84 59.630 -25.793 29.013 1.00107.21 C +ATOM 13988 OE1 GLN H 84 60.583 -26.060 28.281 1.00 81.30 O +ATOM 13989 NE2 GLN H 84 59.074 -26.693 29.817 1.00134.06 N +ATOM 13990 N GLY H 85 60.425 -20.846 30.850 1.00 81.88 N +ATOM 13991 CA GLY H 85 60.378 -20.334 32.209 1.00 84.09 C +ATOM 13992 C GLY H 85 60.415 -18.818 32.287 1.00 80.39 C +ATOM 13993 O GLY H 85 61.105 -18.269 33.154 1.00 90.92 O +ATOM 13994 N LEU H 86 59.720 -18.136 31.369 1.00 66.02 N +ATOM 13995 CA LEU H 86 59.925 -16.692 31.166 1.00 64.97 C +ATOM 13996 C LEU H 86 59.642 -15.897 32.434 1.00 73.92 C +ATOM 13997 O LEU H 86 60.335 -14.910 32.733 1.00 70.66 O +ATOM 13998 CB LEU H 86 59.040 -16.161 30.047 1.00 62.67 C +ATOM 13999 CG LEU H 86 58.962 -14.637 29.793 1.00 66.71 C +ATOM 14000 CD1 LEU H 86 60.291 -14.003 29.447 1.00 53.68 C +ATOM 14001 CD2 LEU H 86 57.957 -14.376 28.663 1.00 84.68 C +ATOM 14002 N GLN H 87 58.701 -16.387 33.229 1.00 75.40 N +ATOM 14003 CA GLN H 87 58.308 -15.667 34.420 1.00 93.52 C +ATOM 14004 C GLN H 87 59.490 -15.517 35.410 1.00 95.78 C +ATOM 14005 O GLN H 87 59.711 -14.434 36.004 1.00 71.01 O +ATOM 14006 CB GLN H 87 57.090 -16.351 35.060 1.00105.50 C +ATOM 14007 CG GLN H 87 56.108 -15.381 35.723 1.00118.01 C +ATOM 14008 CD GLN H 87 55.829 -14.115 34.899 1.00122.26 C +ATOM 14009 OE1 GLN H 87 55.414 -14.185 33.737 1.00 83.08 O +ATOM 14010 NE2 GLN H 87 56.066 -12.951 35.501 1.00130.79 N +ATOM 14011 N ASN H 88 60.241 -16.606 35.600 1.00 92.72 N +ATOM 14012 CA ASN H 88 61.387 -16.608 36.537 1.00 86.81 C +ATOM 14013 C ASN H 88 62.493 -15.686 36.061 1.00 74.60 C +ATOM 14014 O ASN H 88 63.190 -15.052 36.837 1.00 57.28 O +ATOM 14015 CB ASN H 88 61.959 -18.001 36.652 1.00 88.36 C +ATOM 14016 CG ASN H 88 60.937 -18.991 37.079 1.00107.70 C +ATOM 14017 OD1 ASN H 88 60.098 -18.684 37.937 1.00140.18 O +ATOM 14018 ND2 ASN H 88 60.989 -20.196 36.510 1.00119.36 N +ATOM 14019 N LEU H 89 62.623 -15.615 34.748 1.00 72.99 N +ATOM 14020 CA LEU H 89 63.646 -14.821 34.132 1.00 73.76 C +ATOM 14021 C LEU H 89 63.337 -13.365 34.469 1.00 68.44 C +ATOM 14022 O LEU H 89 64.237 -12.580 34.808 1.00 73.66 O +ATOM 14023 CB LEU H 89 63.643 -15.104 32.613 1.00 99.41 C +ATOM 14024 CG LEU H 89 64.940 -14.976 31.815 1.00109.09 C +ATOM 14025 CD1 LEU H 89 64.802 -13.845 30.814 1.00123.99 C +ATOM 14026 CD2 LEU H 89 66.135 -14.736 32.716 1.00108.32 C +ATOM 14027 N LEU H 90 62.059 -13.007 34.372 1.00 70.32 N +ATOM 14028 CA LEU H 90 61.652 -11.611 34.564 1.00 71.59 C +ATOM 14029 C LEU H 90 61.775 -11.239 36.038 1.00 74.32 C +ATOM 14030 O LEU H 90 62.041 -10.094 36.387 1.00 64.81 O +ATOM 14031 CB LEU H 90 60.225 -11.420 34.081 1.00 65.10 C +ATOM 14032 CG LEU H 90 60.001 -11.697 32.606 1.00 67.23 C +ATOM 14033 CD1 LEU H 90 58.535 -11.917 32.330 1.00 65.74 C +ATOM 14034 CD2 LEU H 90 60.543 -10.520 31.805 1.00 85.73 C +ATOM 14035 N ASN H 91 61.586 -12.238 36.897 1.00 76.12 N +ATOM 14036 CA ASN H 91 61.710 -12.064 38.342 1.00 68.42 C +ATOM 14037 C ASN H 91 63.154 -11.822 38.775 1.00 61.65 C +ATOM 14038 O ASN H 91 63.439 -10.856 39.467 1.00 58.38 O +ATOM 14039 CB ASN H 91 61.188 -13.317 39.026 1.00 91.46 C +ATOM 14040 CG ASN H 91 59.979 -13.090 39.887 1.00106.63 C +ATOM 14041 OD1 ASN H 91 59.217 -12.146 39.712 1.00106.26 O +ATOM 14042 ND2 ASN H 91 59.769 -14.028 40.797 1.00138.23 N +ATOM 14043 N GLU H 92 64.082 -12.644 38.284 1.00 64.20 N +ATOM 14044 CA GLU H 92 65.527 -12.385 38.509 1.00 70.07 C +ATOM 14045 C GLU H 92 65.985 -11.007 37.999 1.00 70.10 C +ATOM 14046 O GLU H 92 66.778 -10.320 38.646 1.00 72.96 O +ATOM 14047 CB GLU H 92 66.422 -13.453 37.859 1.00 60.01 C +ATOM 14048 CG GLU H 92 66.726 -14.661 38.733 1.00 47.32 C +ATOM 14049 CD GLU H 92 67.307 -14.334 40.099 1.00 41.18 C +ATOM 14050 OE1 GLU H 92 68.330 -13.617 40.191 1.00 48.44 O +ATOM 14051 OE2 GLU H 92 66.661 -14.682 41.115 1.00 37.43 O +ATOM 14052 N ARG H 93 65.405 -10.576 36.887 1.00 66.54 N +ATOM 14053 CA ARG H 93 65.672 -9.251 36.366 1.00 71.54 C +ATOM 14054 C ARG H 93 65.065 -8.130 37.248 1.00 70.13 C +ATOM 14055 O ARG H 93 65.675 -7.078 37.440 1.00 51.30 O +ATOM 14056 CB ARG H 93 65.210 -9.168 34.904 1.00 73.92 C +ATOM 14057 CG ARG H 93 66.065 -10.049 33.972 1.00 74.60 C +ATOM 14058 CD ARG H 93 65.468 -10.310 32.573 1.00 55.06 C +ATOM 14059 NE ARG H 93 66.063 -9.535 31.493 1.00 40.34 N +ATOM 14060 CZ ARG H 93 65.621 -8.346 31.132 1.00 56.41 C +ATOM 14061 NH1 ARG H 93 64.492 -7.810 31.658 1.00105.13 N +ATOM 14062 NH2 ARG H 93 66.215 -7.718 30.161 1.00 56.70 N +ATOM 14063 N LYS H 94 63.923 -8.390 37.869 1.00 84.47 N +ATOM 14064 CA LYS H 94 63.398 -7.458 38.870 1.00 90.44 C +ATOM 14065 C LYS H 94 64.377 -7.323 40.037 1.00 74.95 C +ATOM 14066 O LYS H 94 64.562 -6.224 40.575 1.00 59.19 O +ATOM 14067 CB LYS H 94 62.038 -7.931 39.396 1.00101.73 C +ATOM 14068 CG LYS H 94 60.838 -7.474 38.584 1.00112.79 C +ATOM 14069 CD LYS H 94 59.577 -8.166 39.081 1.00133.73 C +ATOM 14070 CE LYS H 94 58.298 -7.440 38.678 1.00142.55 C +ATOM 14071 NZ LYS H 94 57.116 -8.324 38.878 1.00143.51 N +ATOM 14072 N ILE H 95 64.932 -8.457 40.471 1.00 69.43 N +ATOM 14073 CA ILE H 95 65.768 -8.474 41.671 1.00 91.72 C +ATOM 14074 C ILE H 95 67.086 -7.788 41.412 1.00 86.94 C +ATOM 14075 O ILE H 95 67.586 -7.025 42.284 1.00120.23 O +ATOM 14076 CB ILE H 95 66.077 -9.890 42.203 1.00102.05 C +ATOM 14077 CG1 ILE H 95 64.790 -10.729 42.312 1.00 92.87 C +ATOM 14078 CG2 ILE H 95 66.704 -9.750 43.582 1.00100.78 C +ATOM 14079 CD1 ILE H 95 64.930 -11.996 43.121 1.00 84.19 C +ATOM 14080 N ILE H 96 67.630 -8.059 40.225 1.00 64.72 N +ATOM 14081 CA ILE H 96 68.748 -7.301 39.725 1.00 65.42 C +ATOM 14082 C ILE H 96 68.471 -5.788 39.776 1.00 70.34 C +ATOM 14083 O ILE H 96 69.210 -5.035 40.417 1.00 80.55 O +ATOM 14084 CB ILE H 96 69.124 -7.684 38.289 1.00 67.23 C +ATOM 14085 CG1 ILE H 96 69.599 -9.119 38.253 1.00 73.50 C +ATOM 14086 CG2 ILE H 96 70.243 -6.781 37.776 1.00 67.52 C +ATOM 14087 CD1 ILE H 96 70.060 -9.553 36.872 1.00 88.61 C +ATOM 14088 N ARG H 97 67.447 -5.343 39.070 1.00 79.74 N +ATOM 14089 CA ARG H 97 67.188 -3.915 38.946 1.00 93.41 C +ATOM 14090 C ARG H 97 66.989 -3.297 40.326 1.00 88.45 C +ATOM 14091 O ARG H 97 67.231 -2.099 40.522 1.00 90.84 O +ATOM 14092 CB ARG H 97 65.966 -3.656 38.040 1.00 97.62 C +ATOM 14093 CG ARG H 97 66.304 -3.164 36.636 1.00100.79 C +ATOM 14094 CD ARG H 97 65.044 -2.858 35.823 1.00110.22 C +ATOM 14095 NE ARG H 97 64.438 -4.049 35.237 1.00111.98 N +ATOM 14096 CZ ARG H 97 64.637 -4.464 33.987 1.00125.10 C +ATOM 14097 NH1 ARG H 97 65.417 -3.781 33.143 1.00119.72 N +ATOM 14098 NH2 ARG H 97 64.073 -5.596 33.580 1.00137.72 N +ATOM 14099 N ALA H 98 66.448 -4.084 41.251 1.00 72.97 N +ATOM 14100 CA ALA H 98 66.166 -3.571 42.570 1.00 86.63 C +ATOM 14101 C ALA H 98 67.449 -3.465 43.358 1.00 72.47 C +ATOM 14102 O ALA H 98 67.590 -2.605 44.253 1.00 66.24 O +ATOM 14103 CB ALA H 98 65.174 -4.470 43.282 1.00107.47 C +ATOM 14104 N ALA H 99 68.392 -4.319 42.997 1.00 73.77 N +ATOM 14105 CA ALA H 99 69.715 -4.331 43.642 1.00104.80 C +ATOM 14106 C ALA H 99 70.577 -3.075 43.326 1.00 82.58 C +ATOM 14107 O ALA H 99 71.085 -2.415 44.218 1.00 41.76 O +ATOM 14108 CB ALA H 99 70.486 -5.595 43.250 1.00106.73 C +ATOM 14109 N GLN H 100 70.672 -2.749 42.050 1.00 76.09 N +ATOM 14110 CA GLN H 100 71.681 -1.823 41.592 1.00 72.96 C +ATOM 14111 C GLN H 100 71.128 -0.468 41.198 1.00 86.16 C +ATOM 14112 O GLN H 100 71.858 0.367 40.661 1.00 95.83 O +ATOM 14113 CB GLN H 100 72.467 -2.441 40.428 1.00 90.71 C +ATOM 14114 CG GLN H 100 71.637 -3.184 39.384 1.00 95.47 C +ATOM 14115 CD GLN H 100 72.426 -4.286 38.669 1.00105.09 C +ATOM 14116 OE1 GLN H 100 72.902 -5.274 39.286 1.00 63.62 O +ATOM 14117 NE2 GLN H 100 72.498 -4.162 37.351 1.00100.14 N +ATOM 14118 N GLU H 101 69.839 -0.241 41.447 1.00101.22 N +ATOM 14119 CA GLU H 101 69.193 1.035 41.068 1.00 95.74 C +ATOM 14120 C GLU H 101 69.719 2.245 41.860 1.00 92.73 C +ATOM 14121 O GLU H 101 69.650 3.373 41.398 1.00 57.68 O +ATOM 14122 CB GLU H 101 67.670 0.942 41.208 1.00 88.04 C +ATOM 14123 CG GLU H 101 67.187 0.447 42.565 1.00 95.35 C +ATOM 14124 CD GLU H 101 65.668 0.461 42.689 1.00101.80 C +ATOM 14125 OE1 GLU H 101 64.995 0.519 41.644 1.00103.01 O +ATOM 14126 OE2 GLU H 101 65.147 0.399 43.825 1.00 95.97 O +ATOM 14127 N ASN H 102 70.282 1.995 43.037 1.00102.78 N +ATOM 14128 CA ASN H 102 70.779 3.078 43.876 1.00 96.83 C +ATOM 14129 C ASN H 102 72.254 3.399 43.670 1.00102.74 C +ATOM 14130 O ASN H 102 72.795 4.281 44.322 1.00 87.88 O +ATOM 14131 CB ASN H 102 70.522 2.745 45.336 1.00104.41 C +ATOM 14132 CG ASN H 102 69.052 2.826 45.678 1.00105.95 C +ATOM 14133 OD1 ASN H 102 68.487 3.919 45.847 1.00 62.64 O +ATOM 14134 ND2 ASN H 102 68.412 1.658 45.748 1.00116.95 N +ATOM 14135 N GLY H 103 72.919 2.651 42.797 1.00122.87 N +ATOM 14136 CA GLY H 103 74.353 2.845 42.576 1.00129.74 C +ATOM 14137 C GLY H 103 75.231 2.688 43.819 1.00133.92 C +ATOM 14138 O GLY H 103 76.237 3.373 43.986 1.00104.16 O +ATOM 14139 N THR H 104 74.847 1.771 44.695 1.00155.25 N +ATOM 14140 CA THR H 104 75.717 1.361 45.773 1.00150.30 C +ATOM 14141 C THR H 104 76.387 0.041 45.427 1.00102.43 C +ATOM 14142 O THR H 104 77.480 -0.215 45.881 1.00103.94 O +ATOM 14143 CB THR H 104 74.957 1.248 47.121 1.00191.08 C +ATOM 14144 OG1 THR H 104 73.972 0.209 47.067 1.00184.35 O +ATOM 14145 CG2 THR H 104 74.273 2.577 47.474 1.00190.31 C +ATOM 14146 N VAL H 105 75.733 -0.783 44.623 1.00 84.15 N +ATOM 14147 CA VAL H 105 76.223 -2.127 44.391 1.00112.28 C +ATOM 14148 C VAL H 105 77.650 -2.091 43.819 1.00132.10 C +ATOM 14149 O VAL H 105 77.983 -1.276 42.941 1.00 82.46 O +ATOM 14150 CB VAL H 105 75.258 -2.999 43.513 1.00142.21 C +ATOM 14151 CG1 VAL H 105 76.017 -4.004 42.629 1.00159.47 C +ATOM 14152 CG2 VAL H 105 74.257 -3.752 44.385 1.00107.29 C +ATOM 14153 N ALA H 106 78.458 -3.044 44.298 1.00157.43 N +ATOM 14154 CA ALA H 106 79.884 -3.128 43.996 1.00135.15 C +ATOM 14155 C ALA H 106 80.126 -3.346 42.505 1.00154.76 C +ATOM 14156 O ALA H 106 79.494 -4.202 41.881 1.00222.89 O +ATOM 14157 CB ALA H 106 80.524 -4.249 44.808 1.00105.35 C +ATOM 14158 N ILE H 107 81.048 -2.570 41.946 1.00147.63 N +ATOM 14159 CA ILE H 107 81.300 -2.564 40.506 1.00137.26 C +ATOM 14160 C ILE H 107 81.695 -3.955 39.951 1.00133.85 C +ATOM 14161 O ILE H 107 81.399 -4.290 38.802 1.00122.07 O +ATOM 14162 CB ILE H 107 82.384 -1.516 40.161 1.00143.63 C +ATOM 14163 CG1 ILE H 107 82.447 -1.268 38.653 1.00150.95 C +ATOM 14164 CG2 ILE H 107 83.752 -1.946 40.693 1.00143.98 C +ATOM 14165 CD1 ILE H 107 81.137 -0.816 38.036 1.00146.77 C +ATOM 14166 N ASN H 108 82.346 -4.766 40.781 1.00132.87 N +ATOM 14167 CA ASN H 108 82.687 -6.151 40.429 1.00124.78 C +ATOM 14168 C ASN H 108 81.443 -7.028 40.378 1.00135.35 C +ATOM 14169 O ASN H 108 81.347 -7.953 39.573 1.00176.38 O +ATOM 14170 CB ASN H 108 83.662 -6.749 41.455 1.00130.36 C +ATOM 14171 CG ASN H 108 84.577 -5.706 42.074 1.00162.88 C +ATOM 14172 OD1 ASN H 108 85.631 -5.386 41.524 1.00197.41 O +ATOM 14173 ND2 ASN H 108 84.167 -5.156 43.213 1.00164.62 N +ATOM 14174 N ASN H 109 80.503 -6.740 41.269 1.00151.18 N +ATOM 14175 CA ASN H 109 79.306 -7.557 41.442 1.00146.69 C +ATOM 14176 C ASN H 109 78.182 -7.178 40.481 1.00133.54 C +ATOM 14177 O ASN H 109 77.230 -7.940 40.284 1.00137.31 O +ATOM 14178 CB ASN H 109 78.824 -7.444 42.890 1.00156.58 C +ATOM 14179 CG ASN H 109 78.886 -8.764 43.619 1.00183.70 C +ATOM 14180 OD1 ASN H 109 77.855 -9.326 43.985 1.00247.59 O +ATOM 14181 ND2 ASN H 109 80.094 -9.297 43.792 1.00170.90 N +ATOM 14182 N ARG H 110 78.301 -5.988 39.892 1.00127.91 N +ATOM 14183 CA ARG H 110 77.238 -5.379 39.073 1.00109.42 C +ATOM 14184 C ARG H 110 76.836 -6.303 37.919 1.00 93.37 C +ATOM 14185 O ARG H 110 77.709 -6.835 37.229 1.00 73.03 O +ATOM 14186 CB ARG H 110 77.740 -4.025 38.516 1.00 99.02 C +ATOM 14187 CG ARG H 110 76.649 -3.043 38.125 1.00102.74 C +ATOM 14188 CD ARG H 110 77.064 -1.604 38.380 1.00112.06 C +ATOM 14189 NE ARG H 110 77.768 -1.010 37.235 1.00108.49 N +ATOM 14190 CZ ARG H 110 77.364 0.078 36.568 1.00127.40 C +ATOM 14191 NH1 ARG H 110 76.236 0.721 36.904 1.00140.34 N +ATOM 14192 NH2 ARG H 110 78.096 0.543 35.559 1.00103.02 N +ATOM 14193 N ILE H 111 75.532 -6.464 37.691 1.00 80.77 N +ATOM 14194 CA ILE H 111 75.061 -7.179 36.502 1.00 88.30 C +ATOM 14195 C ILE H 111 74.437 -6.235 35.492 1.00 92.82 C +ATOM 14196 O ILE H 111 73.433 -5.615 35.786 1.00 96.95 O +ATOM 14197 CB ILE H 111 74.016 -8.237 36.856 1.00 94.88 C +ATOM 14198 CG1 ILE H 111 74.655 -9.302 37.770 1.00110.88 C +ATOM 14199 CG2 ILE H 111 73.464 -8.880 35.584 1.00 89.00 C +ATOM 14200 CD1 ILE H 111 73.680 -10.268 38.431 1.00 80.01 C +ATOM 14201 N PRO H 112 75.045 -6.111 34.300 1.00 91.39 N +ATOM 14202 CA PRO H 112 74.528 -5.189 33.299 1.00 87.95 C +ATOM 14203 C PRO H 112 73.331 -5.774 32.559 1.00 99.99 C +ATOM 14204 O PRO H 112 73.386 -6.925 32.096 1.00117.91 O +ATOM 14205 CB PRO H 112 75.709 -5.018 32.357 1.00 98.73 C +ATOM 14206 CG PRO H 112 76.419 -6.336 32.412 1.00111.51 C +ATOM 14207 CD PRO H 112 76.156 -6.926 33.773 1.00101.33 C +ATOM 14208 N LEU H 113 72.246 -5.002 32.497 1.00125.65 N +ATOM 14209 CA LEU H 113 70.967 -5.483 31.979 1.00116.95 C +ATOM 14210 C LEU H 113 70.582 -4.844 30.666 1.00 82.93 C +ATOM 14211 O LEU H 113 70.742 -3.637 30.425 1.00 61.08 O +ATOM 14212 CB LEU H 113 69.831 -5.230 32.965 1.00131.16 C +ATOM 14213 CG LEU H 113 69.623 -6.296 34.038 1.00119.45 C +ATOM 14214 CD1 LEU H 113 68.397 -5.894 34.823 1.00123.16 C +ATOM 14215 CD2 LEU H 113 69.453 -7.690 33.466 1.00104.97 C +ATOM 14216 N GLN H 114 70.047 -5.696 29.826 1.00 75.89 N +ATOM 14217 CA GLN H 114 69.843 -5.366 28.451 1.00103.62 C +ATOM 14218 C GLN H 114 68.525 -6.012 28.111 1.00 92.53 C +ATOM 14219 O GLN H 114 68.185 -7.052 28.679 1.00 91.16 O +ATOM 14220 CB GLN H 114 70.975 -5.944 27.584 1.00127.77 C +ATOM 14221 CG GLN H 114 71.311 -5.111 26.347 1.00101.72 C +ATOM 14222 CD GLN H 114 71.936 -5.954 25.263 1.00119.69 C +ATOM 14223 OE1 GLN H 114 72.570 -6.987 25.554 1.00153.41 O +ATOM 14224 NE2 GLN H 114 71.662 -5.605 24.008 1.00103.71 N +ATOM 14225 N SER H 115 67.792 -5.381 27.201 1.00 74.38 N +ATOM 14226 CA SER H 115 66.476 -5.817 26.851 1.00 74.42 C +ATOM 14227 C SER H 115 66.539 -7.274 26.422 1.00 71.47 C +ATOM 14228 O SER H 115 67.572 -7.754 25.926 1.00 46.29 O +ATOM 14229 CB SER H 115 65.877 -4.927 25.754 1.00 88.42 C +ATOM 14230 OG SER H 115 66.759 -4.807 24.637 1.00157.74 O +ATOM 14231 N LEU H 116 65.408 -7.968 26.552 1.00 94.80 N +ATOM 14232 CA LEU H 116 65.420 -9.398 26.345 1.00 99.39 C +ATOM 14233 C LEU H 116 65.567 -9.642 24.860 1.00123.42 C +ATOM 14234 O LEU H 116 64.814 -9.078 24.067 1.00103.01 O +ATOM 14235 CB LEU H 116 64.149 -10.063 26.856 1.00 82.13 C +ATOM 14236 CG LEU H 116 63.944 -10.000 28.360 1.00 77.67 C +ATOM 14237 CD1 LEU H 116 63.070 -8.787 28.743 1.00 72.73 C +ATOM 14238 CD2 LEU H 116 63.302 -11.311 28.800 1.00 72.05 C +ATOM 14239 N THR H 117 66.586 -10.418 24.493 1.00143.51 N +ATOM 14240 CA THR H 117 66.848 -10.759 23.098 1.00140.50 C +ATOM 14241 C THR H 117 65.606 -11.387 22.503 1.00104.44 C +ATOM 14242 O THR H 117 64.974 -12.230 23.149 1.00 80.13 O +ATOM 14243 CB THR H 117 67.991 -11.780 22.962 1.00153.08 C +ATOM 14244 OG1 THR H 117 69.164 -11.292 23.627 1.00163.60 O +ATOM 14245 CG2 THR H 117 68.312 -12.005 21.501 1.00161.41 C +ATOM 14246 N ALA H 118 65.226 -10.919 21.317 1.00 99.19 N +ATOM 14247 CA ALA H 118 63.911 -11.222 20.758 1.00102.06 C +ATOM 14248 C ALA H 118 64.053 -12.061 19.506 1.00105.36 C +ATOM 14249 O ALA H 118 64.881 -11.769 18.651 1.00 72.34 O +ATOM 14250 CB ALA H 118 63.114 -9.947 20.455 1.00 66.92 C +ATOM 14251 N ALA H 119 63.133 -13.020 19.372 1.00108.32 N +ATOM 14252 CA ALA H 119 63.151 -14.005 18.297 1.00 86.85 C +ATOM 14253 C ALA H 119 62.441 -13.519 17.045 1.00 71.85 C +ATOM 14254 O ALA H 119 61.538 -12.671 17.135 1.00 64.66 O +ATOM 14255 CB ALA H 119 62.506 -15.287 18.779 1.00 81.20 C +ATOM 14256 N ASN H 120 62.824 -14.058 15.892 1.00 72.69 N +ATOM 14257 CA ASN H 120 62.117 -13.722 14.669 1.00108.96 C +ATOM 14258 C ASN H 120 61.117 -14.794 14.277 1.00114.06 C +ATOM 14259 O ASN H 120 59.991 -14.497 13.848 1.00147.74 O +ATOM 14260 CB ASN H 120 63.060 -13.473 13.494 1.00131.90 C +ATOM 14261 CG ASN H 120 62.303 -13.023 12.225 1.00131.21 C +ATOM 14262 OD1 ASN H 120 62.631 -13.498 11.134 1.00189.63 O +ATOM 14263 ND2 ASN H 120 61.246 -12.175 12.368 1.00 66.01 N +ATOM 14264 N ILE H 121 61.549 -16.041 14.333 1.00 92.19 N +ATOM 14265 CA ILE H 121 60.626 -17.126 14.069 1.00 97.19 C +ATOM 14266 C ILE H 121 60.451 -17.834 15.385 1.00 97.02 C +ATOM 14267 O ILE H 121 61.386 -17.955 16.174 1.00100.71 O +ATOM 14268 CB ILE H 121 61.116 -18.099 12.966 1.00107.98 C +ATOM 14269 CG1 ILE H 121 62.299 -18.969 13.447 1.00127.17 C +ATOM 14270 CG2 ILE H 121 61.488 -17.337 11.700 1.00108.45 C +ATOM 14271 CD1 ILE H 121 61.949 -20.429 13.627 1.00112.28 C +ATOM 14272 N MET H 122 59.240 -18.279 15.646 1.00 78.37 N +ATOM 14273 CA MET H 122 59.056 -19.172 16.757 1.00 60.05 C +ATOM 14274 C MET H 122 58.422 -20.443 16.262 1.00 59.04 C +ATOM 14275 O MET H 122 57.667 -20.450 15.271 1.00 77.48 O +ATOM 14276 CB MET H 122 58.214 -18.500 17.828 1.00 71.00 C +ATOM 14277 CG MET H 122 56.843 -17.988 17.385 1.00 66.51 C +ATOM 14278 SD MET H 122 55.717 -18.102 18.788 1.00 82.83 S +ATOM 14279 CE MET H 122 54.211 -18.645 18.039 1.00 73.89 C +ATOM 14280 N VAL H 123 58.809 -21.549 16.864 1.00 69.05 N +ATOM 14281 CA VAL H 123 58.353 -22.855 16.393 1.00 98.00 C +ATOM 14282 C VAL H 123 57.606 -23.516 17.515 1.00102.89 C +ATOM 14283 O VAL H 123 58.132 -23.693 18.596 1.00109.13 O +ATOM 14284 CB VAL H 123 59.507 -23.792 15.924 1.00122.74 C +ATOM 14285 CG1 VAL H 123 60.725 -23.671 16.830 1.00127.78 C +ATOM 14286 CG2 VAL H 123 59.036 -25.246 15.834 1.00129.93 C +ATOM 14287 N GLU H 124 56.383 -23.934 17.228 1.00126.91 N +ATOM 14288 CA GLU H 124 55.618 -24.741 18.179 1.00108.39 C +ATOM 14289 C GLU H 124 55.100 -25.985 17.512 1.00 91.44 C +ATOM 14290 O GLU H 124 55.165 -26.142 16.286 1.00102.17 O +ATOM 14291 CB GLU H 124 54.461 -23.943 18.765 1.00126.61 C +ATOM 14292 CG GLU H 124 53.883 -22.866 17.851 1.00146.16 C +ATOM 14293 CD GLU H 124 53.074 -21.849 18.627 1.00152.54 C +ATOM 14294 OE1 GLU H 124 53.460 -21.527 19.777 1.00143.59 O +ATOM 14295 OE2 GLU H 124 52.036 -21.411 18.094 1.00160.61 O +ATOM 14296 N GLY H 125 54.557 -26.866 18.323 1.00 78.80 N +ATOM 14297 CA GLY H 125 54.094 -28.144 17.816 1.00 77.68 C +ATOM 14298 C GLY H 125 53.353 -28.929 18.874 1.00 70.34 C +ATOM 14299 O GLY H 125 52.911 -28.376 19.888 1.00 70.13 O +ATOM 14300 N SER H 126 53.236 -30.230 18.658 1.00 64.76 N +ATOM 14301 CA SER H 126 52.459 -31.058 19.552 1.00 78.48 C +ATOM 14302 C SER H 126 52.894 -32.502 19.391 1.00 57.60 C +ATOM 14303 O SER H 126 53.185 -32.906 18.284 1.00 39.17 O +ATOM 14304 CB SER H 126 50.954 -30.903 19.236 1.00108.03 C +ATOM 14305 OG SER H 126 50.606 -29.607 18.733 1.00141.50 O +ATOM 14306 N ILE H 127 52.795 -33.273 20.470 1.00 44.00 N +ATOM 14307 CA ILE H 127 52.752 -34.677 20.323 1.00 57.88 C +ATOM 14308 C ILE H 127 51.376 -35.104 19.851 1.00 73.97 C +ATOM 14309 O ILE H 127 50.432 -35.191 20.608 1.00 81.14 O +ATOM 14310 CB ILE H 127 53.110 -35.413 21.603 1.00 75.24 C +ATOM 14311 CG1 ILE H 127 54.572 -35.096 21.985 1.00 94.00 C +ATOM 14312 CG2 ILE H 127 52.940 -36.933 21.425 1.00 83.79 C +ATOM 14313 CD1 ILE H 127 54.845 -35.127 23.483 1.00 85.96 C +ATOM 14314 N ILE H 128 51.275 -35.376 18.550 1.00104.39 N +ATOM 14315 CA ILE H 128 50.028 -35.832 17.895 1.00 80.94 C +ATOM 14316 C ILE H 128 50.061 -37.361 17.920 1.00 86.26 C +ATOM 14317 O ILE H 128 50.807 -38.011 17.188 1.00118.57 O +ATOM 14318 CB ILE H 128 49.917 -35.259 16.460 1.00 63.64 C +ATOM 14319 CG1 ILE H 128 51.169 -35.581 15.626 1.00 86.23 C +ATOM 14320 CG2 ILE H 128 49.891 -33.741 16.514 1.00 65.89 C +ATOM 14321 CD1 ILE H 128 50.927 -35.576 14.127 1.00 74.79 C +ATOM 14322 N GLY H 129 49.404 -37.918 18.912 1.00 78.28 N +ATOM 14323 CA GLY H 129 49.093 -39.318 18.878 1.00 76.68 C +ATOM 14324 C GLY H 129 50.124 -40.233 19.483 1.00 81.21 C +ATOM 14325 O GLY H 129 51.358 -40.138 19.229 1.00 70.25 O +ATOM 14326 N TYR H 130 49.591 -41.207 20.219 1.00 78.32 N +ATOM 14327 CA TYR H 130 50.342 -42.394 20.579 1.00 99.30 C +ATOM 14328 C TYR H 130 49.329 -43.489 20.495 1.00 95.14 C +ATOM 14329 O TYR H 130 48.452 -43.589 21.333 1.00104.93 O +ATOM 14330 CB TYR H 130 50.948 -42.274 22.002 1.00110.50 C +ATOM 14331 CG TYR H 130 51.643 -43.508 22.566 1.00 92.65 C +ATOM 14332 CD1 TYR H 130 50.909 -44.647 22.912 1.00 76.22 C +ATOM 14333 CD2 TYR H 130 53.018 -43.503 22.809 1.00100.22 C +ATOM 14334 CE1 TYR H 130 51.529 -45.756 23.438 1.00 74.98 C +ATOM 14335 CE2 TYR H 130 53.656 -44.630 23.286 1.00102.67 C +ATOM 14336 CZ TYR H 130 52.910 -45.748 23.608 1.00 81.35 C +ATOM 14337 OH TYR H 130 53.566 -46.848 24.118 1.00 81.72 O +ATOM 14338 N GLU H 131 49.466 -44.333 19.481 1.00119.88 N +ATOM 14339 CA GLU H 131 48.684 -45.564 19.412 1.00138.04 C +ATOM 14340 C GLU H 131 49.513 -46.744 19.902 1.00 95.08 C +ATOM 14341 O GLU H 131 50.734 -46.726 19.796 1.00 72.97 O +ATOM 14342 CB GLU H 131 48.229 -45.788 17.981 1.00159.13 C +ATOM 14343 CG GLU H 131 47.191 -46.878 17.801 1.00148.00 C +ATOM 14344 CD GLU H 131 45.760 -46.387 17.982 1.00125.74 C +ATOM 14345 OE1 GLU H 131 45.485 -45.183 17.704 1.00 76.63 O +ATOM 14346 OE2 GLU H 131 44.903 -47.231 18.349 1.00154.43 O +ATOM 14347 N SER H 132 48.857 -47.708 20.539 1.00 84.30 N +ATOM 14348 CA SER H 132 49.575 -48.751 21.265 1.00 96.30 C +ATOM 14349 C SER H 132 49.258 -50.134 20.718 1.00102.18 C +ATOM 14350 O SER H 132 48.105 -50.427 20.388 1.00132.60 O +ATOM 14351 CB SER H 132 49.262 -48.694 22.772 1.00102.73 C +ATOM 14352 OG SER H 132 48.538 -49.849 23.192 1.00 96.74 O +ATOM 14353 N ASN H 133 50.272 -50.997 20.675 1.00101.74 N +ATOM 14354 CA ASN H 133 50.177 -52.283 19.962 1.00108.59 C +ATOM 14355 C ASN H 133 49.569 -52.122 18.574 1.00 92.14 C +ATOM 14356 O ASN H 133 48.552 -52.736 18.247 1.00 77.20 O +ATOM 14357 CB ASN H 133 49.365 -53.307 20.754 1.00109.13 C +ATOM 14358 CG ASN H 133 49.968 -53.599 22.101 1.00126.44 C +ATOM 14359 OD1 ASN H 133 51.194 -53.499 22.303 1.00159.76 O +ATOM 14360 ND2 ASN H 133 49.112 -53.935 23.050 1.00118.16 N +ATOM 14361 N VAL H 134 50.184 -51.251 17.790 1.00 81.08 N +ATOM 14362 CA VAL H 134 49.742 -50.989 16.442 1.00 95.64 C +ATOM 14363 C VAL H 134 49.980 -52.265 15.636 1.00123.95 C +ATOM 14364 O VAL H 134 49.195 -52.618 14.750 1.00202.12 O +ATOM 14365 CB VAL H 134 50.513 -49.793 15.833 1.00106.46 C +ATOM 14366 CG1 VAL H 134 50.010 -49.465 14.437 1.00108.55 C +ATOM 14367 CG2 VAL H 134 50.382 -48.566 16.733 1.00116.35 C +ATOM 14368 N LYS H 135 51.055 -52.977 15.971 1.00133.24 N +ATOM 14369 CA LYS H 135 51.219 -54.370 15.532 1.00 99.26 C +ATOM 14370 C LYS H 135 51.698 -55.242 16.686 1.00 91.85 C +ATOM 14371 O LYS H 135 52.335 -54.754 17.642 1.00 90.19 O +ATOM 14372 CB LYS H 135 52.206 -54.449 14.359 1.00 83.01 C +ATOM 14373 CG LYS H 135 51.738 -53.698 13.132 1.00 69.68 C +ATOM 14374 CD LYS H 135 52.807 -53.713 12.070 1.00 79.91 C +ATOM 14375 CE LYS H 135 52.358 -52.967 10.828 1.00 93.57 C +ATOM 14376 NZ LYS H 135 53.143 -53.408 9.640 1.00 96.33 N +ATOM 14377 N SER H 136 51.500 -56.542 16.527 1.00 84.88 N +ATOM 14378 CA SER H 136 51.977 -57.504 17.504 1.00101.71 C +ATOM 14379 C SER H 136 52.024 -58.926 16.937 1.00119.30 C +ATOM 14380 O SER H 136 51.321 -59.236 15.988 1.00152.42 O +ATOM 14381 CB SER H 136 51.099 -57.445 18.755 1.00 95.38 C +ATOM 14382 OG SER H 136 50.564 -58.721 19.080 1.00 89.17 O +ATOM 14383 N GLY H 137 52.844 -59.783 17.544 1.00131.75 N +ATOM 14384 CA GLY H 137 52.915 -61.186 17.147 1.00149.38 C +ATOM 14385 C GLY H 137 53.650 -62.075 18.137 1.00175.03 C +ATOM 14386 O GLY H 137 54.187 -61.604 19.141 1.00203.30 O +ATOM 14387 N GLY H 138 53.662 -63.375 17.861 1.00186.26 N +ATOM 14388 CA GLY H 138 54.375 -64.331 18.705 1.00185.36 C +ATOM 14389 C GLY H 138 54.589 -65.673 18.037 1.00186.85 C +ATOM 14390 O GLY H 138 53.757 -66.120 17.248 1.00216.84 O +ATOM 14391 N VAL H 139 55.730 -66.295 18.323 1.00174.02 N +ATOM 14392 CA VAL H 139 56.049 -67.618 17.794 1.00151.63 C +ATOM 14393 C VAL H 139 56.701 -68.468 18.875 1.00148.30 C +ATOM 14394 O VAL H 139 57.702 -68.062 19.478 1.00151.27 O +ATOM 14395 CB VAL H 139 57.010 -67.542 16.590 1.00151.69 C +ATOM 14396 CG1 VAL H 139 57.413 -68.943 16.160 1.00158.13 C +ATOM 14397 CG2 VAL H 139 56.375 -66.789 15.429 1.00147.19 C +ATOM 14398 N GLY H 140 56.142 -69.653 19.110 1.00147.45 N +ATOM 14399 CA GLY H 140 56.658 -70.557 20.135 1.00163.01 C +ATOM 14400 C GLY H 140 56.474 -72.027 19.819 1.00172.12 C +ATOM 14401 O GLY H 140 55.487 -72.422 19.205 1.00181.14 O +ATOM 14402 N ALA H 141 57.438 -72.841 20.241 1.00190.24 N +ATOM 14403 CA ALA H 141 57.355 -74.284 20.048 1.00179.27 C +ATOM 14404 C ALA H 141 57.925 -75.054 21.241 1.00182.08 C +ATOM 14405 O ALA H 141 58.923 -74.654 21.845 1.00171.64 O +ATOM 14406 CB ALA H 141 58.057 -74.684 18.761 1.00143.96 C +ATOM 14407 N ARG H 142 57.238 -76.122 21.616 1.00175.81 N +ATOM 14408 CA ARG H 142 57.745 -77.020 22.624 1.00172.59 C +ATOM 14409 C ARG H 142 57.716 -78.437 22.076 1.00212.93 C +ATOM 14410 O ARG H 142 56.827 -78.797 21.300 1.00250.16 O +ATOM 14411 CB ARG H 142 56.937 -76.921 23.920 1.00160.95 C +ATOM 14412 CG ARG H 142 57.506 -77.788 25.039 1.00169.21 C +ATOM 14413 CD ARG H 142 57.502 -77.089 26.385 1.00161.06 C +ATOM 14414 NE ARG H 142 56.200 -77.194 27.031 1.00169.97 N +ATOM 14415 CZ ARG H 142 55.726 -76.342 27.936 1.00178.93 C +ATOM 14416 NH1 ARG H 142 56.448 -75.293 28.313 1.00203.52 N +ATOM 14417 NH2 ARG H 142 54.516 -76.529 28.461 1.00148.99 N +ATOM 14418 N TYR H 143 58.730 -79.218 22.441 1.00229.15 N +ATOM 14419 CA TYR H 143 58.945 -80.546 21.859 1.00181.17 C +ATOM 14420 C TYR H 143 59.175 -81.600 22.943 1.00132.45 C +ATOM 14421 O TYR H 143 60.313 -81.909 23.301 1.00 85.93 O +ATOM 14422 CB TYR H 143 60.134 -80.490 20.906 1.00184.80 C +ATOM 14423 CG TYR H 143 60.363 -81.728 20.115 1.00199.54 C +ATOM 14424 CD1 TYR H 143 59.522 -82.060 19.055 1.00206.65 C +ATOM 14425 CD2 TYR H 143 61.470 -82.521 20.354 1.00201.68 C +ATOM 14426 CE1 TYR H 143 59.767 -83.166 18.265 1.00201.62 C +ATOM 14427 CE2 TYR H 143 61.727 -83.632 19.566 1.00220.23 C +ATOM 14428 CZ TYR H 143 60.870 -83.951 18.527 1.00211.30 C +ATOM 14429 OH TYR H 143 61.118 -85.058 17.749 1.00195.25 O +ATOM 14430 N GLY H 145 59.674 -81.898 25.635 1.00 99.43 N +ATOM 14431 CA GLY H 145 60.266 -81.437 26.888 1.00141.11 C +ATOM 14432 C GLY H 145 60.953 -80.078 26.846 1.00164.10 C +ATOM 14433 O GLY H 145 61.027 -79.396 27.867 1.00184.14 O +ATOM 14434 N ILE H 146 61.399 -79.652 25.660 1.00168.64 N +ATOM 14435 CA ILE H 146 62.198 -78.418 25.512 1.00169.32 C +ATOM 14436 C ILE H 146 61.410 -77.397 24.690 1.00172.84 C +ATOM 14437 O ILE H 146 60.759 -77.755 23.717 1.00194.22 O +ATOM 14438 CB ILE H 146 63.552 -78.682 24.809 1.00174.95 C +ATOM 14439 CG1 ILE H 146 64.161 -80.002 25.295 1.00190.47 C +ATOM 14440 CG2 ILE H 146 64.524 -77.536 25.055 1.00168.28 C +ATOM 14441 CD1 ILE H 146 63.884 -81.182 24.382 1.00193.44 C +ATOM 14442 N GLY H 147 61.423 -76.133 25.100 1.00181.89 N +ATOM 14443 CA GLY H 147 60.588 -75.132 24.430 1.00178.65 C +ATOM 14444 C GLY H 147 61.128 -73.720 24.445 1.00165.38 C +ATOM 14445 O GLY H 147 61.874 -73.338 25.341 1.00154.21 O +ATOM 14446 N ALA H 148 60.733 -72.944 23.444 1.00153.52 N +ATOM 14447 CA ALA H 148 61.056 -71.532 23.405 1.00145.69 C +ATOM 14448 C ALA H 148 59.943 -70.754 22.710 1.00143.47 C +ATOM 14449 O ALA H 148 59.040 -71.326 22.109 1.00135.08 O +ATOM 14450 CB ALA H 148 62.390 -71.304 22.707 1.00123.08 C +ATOM 14451 N ASP H 149 59.967 -69.441 22.890 1.00168.47 N +ATOM 14452 CA ASP H 149 58.966 -68.574 22.280 1.00142.78 C +ATOM 14453 C ASP H 149 59.413 -67.120 22.326 1.00127.90 C +ATOM 14454 O ASP H 149 60.135 -66.713 23.246 1.00112.07 O +ATOM 14455 CB ASP H 149 57.605 -68.732 22.967 1.00157.74 C +ATOM 14456 CG ASP H 149 57.504 -67.943 24.243 1.00179.81 C +ATOM 14457 OD1 ASP H 149 58.085 -68.385 25.253 1.00205.31 O +ATOM 14458 OD2 ASP H 149 56.833 -66.892 24.235 1.00179.68 O +ATOM 14459 N THR H 150 59.054 -66.364 21.296 1.00138.04 N +ATOM 14460 CA THR H 150 59.179 -64.918 21.363 1.00158.62 C +ATOM 14461 C THR H 150 57.822 -64.275 21.131 1.00189.95 C +ATOM 14462 O THR H 150 56.928 -64.870 20.525 1.00235.04 O +ATOM 14463 CB THR H 150 60.184 -64.353 20.335 1.00151.27 C +ATOM 14464 OG1 THR H 150 59.766 -64.704 19.015 1.00117.75 O +ATOM 14465 CG2 THR H 150 61.585 -64.878 20.600 1.00143.31 C +ATOM 14466 N GLN H 151 57.666 -63.077 21.673 1.00191.15 N +ATOM 14467 CA GLN H 151 56.480 -62.269 21.457 1.00161.21 C +ATOM 14468 C GLN H 151 56.906 -60.839 21.246 1.00150.46 C +ATOM 14469 O GLN H 151 57.883 -60.405 21.840 1.00196.43 O +ATOM 14470 CB GLN H 151 55.582 -62.359 22.675 1.00138.78 C +ATOM 14471 CG GLN H 151 54.897 -63.701 22.793 1.00153.29 C +ATOM 14472 CD GLN H 151 54.460 -63.981 24.206 1.00171.25 C +ATOM 14473 OE1 GLN H 151 53.966 -63.086 24.888 1.00186.81 O +ATOM 14474 NE2 GLN H 151 54.631 -65.224 24.657 1.00171.41 N +ATOM 14475 N TYR H 152 56.239 -60.129 20.343 1.00128.31 N +ATOM 14476 CA TYR H 152 56.610 -58.751 20.079 1.00111.39 C +ATOM 14477 C TYR H 152 55.394 -57.871 19.958 1.00107.52 C +ATOM 14478 O TYR H 152 54.353 -58.293 19.460 1.00131.12 O +ATOM 14479 CB TYR H 152 57.515 -58.643 18.838 1.00 89.32 C +ATOM 14480 CG TYR H 152 56.886 -58.111 17.573 1.00 72.65 C +ATOM 14481 CD1 TYR H 152 55.873 -58.807 16.917 1.00 84.66 C +ATOM 14482 CD2 TYR H 152 57.374 -56.958 16.972 1.00 64.07 C +ATOM 14483 CE1 TYR H 152 55.319 -58.324 15.721 1.00 94.95 C +ATOM 14484 CE2 TYR H 152 56.844 -56.468 15.771 1.00 68.79 C +ATOM 14485 CZ TYR H 152 55.820 -57.154 15.138 1.00 90.61 C +ATOM 14486 OH TYR H 152 55.292 -56.684 13.947 1.00 87.07 O +ATOM 14487 N GLN H 153 55.528 -56.632 20.417 1.00115.81 N +ATOM 14488 CA GLN H 153 54.528 -55.606 20.139 1.00114.30 C +ATOM 14489 C GLN H 153 55.209 -54.313 19.684 1.00 93.73 C +ATOM 14490 O GLN H 153 56.368 -54.057 20.046 1.00121.67 O +ATOM 14491 CB GLN H 153 53.682 -55.378 21.389 1.00118.19 C +ATOM 14492 CG GLN H 153 52.831 -56.578 21.815 1.00143.39 C +ATOM 14493 CD GLN H 153 52.089 -56.302 23.130 1.00188.23 C +ATOM 14494 OE1 GLN H 153 52.502 -55.448 23.924 1.00225.29 O +ATOM 14495 NE2 GLN H 153 51.020 -57.054 23.384 1.00213.75 N +ATOM 14496 N LEU H 154 54.510 -53.511 18.889 1.00 64.93 N +ATOM 14497 CA LEU H 154 55.005 -52.182 18.597 1.00 84.68 C +ATOM 14498 C LEU H 154 53.926 -51.093 18.554 1.00107.24 C +ATOM 14499 O LEU H 154 52.788 -51.331 18.125 1.00106.41 O +ATOM 14500 CB LEU H 154 55.786 -52.192 17.303 1.00 76.50 C +ATOM 14501 CG LEU H 154 54.949 -52.362 16.052 1.00 92.57 C +ATOM 14502 CD1 LEU H 154 54.625 -51.016 15.415 1.00 82.36 C +ATOM 14503 CD2 LEU H 154 55.686 -53.264 15.073 1.00133.03 C +ATOM 14504 N ASP H 155 54.348 -49.883 18.950 1.00121.71 N +ATOM 14505 CA ASP H 155 53.479 -48.729 19.199 1.00 95.80 C +ATOM 14506 C ASP H 155 53.924 -47.569 18.302 1.00 83.20 C +ATOM 14507 O ASP H 155 55.032 -47.583 17.794 1.00 54.96 O +ATOM 14508 CB ASP H 155 53.588 -48.299 20.669 1.00 92.37 C +ATOM 14509 CG ASP H 155 53.495 -49.478 21.636 1.00102.77 C +ATOM 14510 OD1 ASP H 155 54.508 -50.174 21.832 1.00104.31 O +ATOM 14511 OD2 ASP H 155 52.410 -49.693 22.212 1.00125.34 O +ATOM 14512 N GLN H 156 53.054 -46.582 18.102 1.00102.47 N +ATOM 14513 CA GLN H 156 53.378 -45.442 17.237 1.00 89.25 C +ATOM 14514 C GLN H 156 53.379 -44.150 18.020 1.00 92.28 C +ATOM 14515 O GLN H 156 52.745 -44.037 19.084 1.00113.44 O +ATOM 14516 CB GLN H 156 52.386 -45.346 16.092 1.00 97.66 C +ATOM 14517 CG GLN H 156 52.798 -44.380 15.007 1.00 95.51 C +ATOM 14518 CD GLN H 156 52.100 -44.670 13.679 1.00132.73 C +ATOM 14519 OE1 GLN H 156 51.165 -45.491 13.600 1.00141.81 O +ATOM 14520 NE2 GLN H 156 52.530 -43.980 12.625 1.00126.16 N +ATOM 14521 N ILE H 157 54.111 -43.175 17.513 1.00 85.73 N +ATOM 14522 CA ILE H 157 54.162 -41.855 18.135 1.00 95.57 C +ATOM 14523 C ILE H 157 54.477 -40.815 17.051 1.00 87.80 C +ATOM 14524 O ILE H 157 55.221 -41.093 16.114 1.00 52.25 O +ATOM 14525 CB ILE H 157 55.228 -41.789 19.245 1.00103.70 C +ATOM 14526 CG1 ILE H 157 54.897 -40.675 20.248 1.00134.33 C +ATOM 14527 CG2 ILE H 157 56.607 -41.554 18.638 1.00109.01 C +ATOM 14528 CD1 ILE H 157 55.801 -40.647 21.471 1.00145.70 C +ATOM 14529 N ALA H 158 53.779 -39.680 17.092 1.00 93.23 N +ATOM 14530 CA ALA H 158 53.899 -38.717 16.004 1.00 84.59 C +ATOM 14531 C ALA H 158 54.014 -37.357 16.578 1.00 63.68 C +ATOM 14532 O ALA H 158 53.509 -37.092 17.675 1.00 71.25 O +ATOM 14533 CB ALA H 158 52.726 -38.794 15.016 1.00 87.75 C +ATOM 14534 N VAL H 159 54.713 -36.501 15.844 1.00 54.28 N +ATOM 14535 CA VAL H 159 55.027 -35.182 16.338 1.00 67.56 C +ATOM 14536 C VAL H 159 54.881 -34.159 15.245 1.00 74.90 C +ATOM 14537 O VAL H 159 55.389 -34.333 14.137 1.00 77.19 O +ATOM 14538 CB VAL H 159 56.444 -35.122 16.917 1.00 93.53 C +ATOM 14539 CG1 VAL H 159 56.960 -33.694 16.974 1.00 98.24 C +ATOM 14540 CG2 VAL H 159 56.488 -35.749 18.314 1.00104.16 C +ATOM 14541 N ASN H 160 54.125 -33.107 15.553 1.00 90.35 N +ATOM 14542 CA ASN H 160 54.037 -31.947 14.684 1.00 81.57 C +ATOM 14543 C ASN H 160 55.002 -30.891 15.199 1.00 75.08 C +ATOM 14544 O ASN H 160 55.044 -30.605 16.394 1.00 82.54 O +ATOM 14545 CB ASN H 160 52.619 -31.406 14.685 1.00 92.34 C +ATOM 14546 CG ASN H 160 52.468 -30.139 13.835 1.00131.51 C +ATOM 14547 OD1 ASN H 160 53.206 -29.167 14.000 1.00171.47 O +ATOM 14548 ND2 ASN H 160 51.400 -30.081 13.056 1.00146.34 N +ATOM 14549 N LEU H 161 55.831 -30.377 14.307 1.00 66.49 N +ATOM 14550 CA LEU H 161 56.527 -29.138 14.562 1.00 67.16 C +ATOM 14551 C LEU H 161 56.225 -28.138 13.453 1.00 74.67 C +ATOM 14552 O LEU H 161 56.030 -28.498 12.302 1.00 73.32 O +ATOM 14553 CB LEU H 161 58.029 -29.376 14.614 1.00 67.84 C +ATOM 14554 CG LEU H 161 58.513 -30.262 15.735 1.00 71.66 C +ATOM 14555 CD1 LEU H 161 59.994 -30.555 15.557 1.00 99.09 C +ATOM 14556 CD2 LEU H 161 58.265 -29.559 17.061 1.00 91.98 C +ATOM 14557 N ARG H 162 56.198 -26.864 13.787 1.00 91.41 N +ATOM 14558 CA ARG H 162 55.881 -25.864 12.781 1.00109.35 C +ATOM 14559 C ARG H 162 56.458 -24.486 13.072 1.00 90.18 C +ATOM 14560 O ARG H 162 56.346 -23.958 14.174 1.00106.13 O +ATOM 14561 CB ARG H 162 54.363 -25.790 12.536 1.00139.03 C +ATOM 14562 CG ARG H 162 53.493 -25.348 13.704 1.00150.27 C +ATOM 14563 CD ARG H 162 52.109 -24.944 13.203 1.00139.78 C +ATOM 14564 NE ARG H 162 51.283 -24.333 14.250 1.00130.31 N +ATOM 14565 CZ ARG H 162 50.583 -25.006 15.170 1.00116.35 C +ATOM 14566 NH1 ARG H 162 50.619 -26.331 15.219 1.00100.87 N +ATOM 14567 NH2 ARG H 162 49.870 -24.338 16.064 1.00103.06 N +ATOM 14568 N VAL H 163 57.086 -23.931 12.048 1.00 91.34 N +ATOM 14569 CA VAL H 163 57.682 -22.604 12.109 1.00110.63 C +ATOM 14570 C VAL H 163 56.610 -21.580 11.810 1.00115.91 C +ATOM 14571 O VAL H 163 56.076 -21.539 10.702 1.00147.67 O +ATOM 14572 CB VAL H 163 58.809 -22.404 11.051 1.00110.05 C +ATOM 14573 CG1 VAL H 163 59.384 -20.983 11.129 1.00 90.12 C +ATOM 14574 CG2 VAL H 163 59.877 -23.482 11.220 1.00109.36 C +ATOM 14575 N VAL H 164 56.449 -20.657 12.743 1.00101.42 N +ATOM 14576 CA VAL H 164 55.558 -19.545 12.566 1.00 85.45 C +ATOM 14577 C VAL H 164 56.376 -18.284 12.449 1.00 71.97 C +ATOM 14578 O VAL H 164 57.273 -18.022 13.278 1.00 87.84 O +ATOM 14579 CB VAL H 164 54.630 -19.433 13.774 1.00128.56 C +ATOM 14580 CG1 VAL H 164 53.704 -18.230 13.633 1.00163.97 C +ATOM 14581 CG2 VAL H 164 53.828 -20.719 13.923 1.00107.17 C +ATOM 14582 N ASN H 165 55.997 -17.455 11.495 1.00 64.32 N +ATOM 14583 CA ASN H 165 56.596 -16.137 11.393 1.00 95.72 C +ATOM 14584 C ASN H 165 55.986 -15.115 12.360 1.00104.80 C +ATOM 14585 O ASN H 165 54.806 -14.764 12.228 1.00139.74 O +ATOM 14586 CB ASN H 165 56.457 -15.592 9.975 1.00103.41 C +ATOM 14587 CG ASN H 165 57.180 -14.274 9.802 1.00 94.91 C +ATOM 14588 OD1 ASN H 165 58.157 -14.008 10.543 1.00142.38 O +ATOM 14589 ND2 ASN H 165 56.929 -13.629 8.672 1.00 88.58 N +ATOM 14590 N VAL H 166 56.811 -14.594 13.268 1.00 83.94 N +ATOM 14591 CA VAL H 166 56.372 -13.628 14.238 1.00 66.09 C +ATOM 14592 C VAL H 166 55.813 -12.414 13.536 1.00 74.42 C +ATOM 14593 O VAL H 166 54.824 -11.828 14.015 1.00159.38 O +ATOM 14594 CB VAL H 166 57.527 -13.213 15.155 1.00 88.70 C +ATOM 14595 CG1 VAL H 166 57.307 -11.828 15.792 1.00101.16 C +ATOM 14596 CG2 VAL H 166 57.763 -14.294 16.210 1.00 95.41 C +ATOM 14597 N SER H 167 56.417 -12.024 12.409 1.00 63.79 N +ATOM 14598 CA SER H 167 56.130 -10.728 11.804 1.00 72.73 C +ATOM 14599 C SER H 167 54.796 -10.725 11.062 1.00 99.93 C +ATOM 14600 O SER H 167 54.237 -9.651 10.773 1.00 83.13 O +ATOM 14601 CB SER H 167 57.244 -10.340 10.853 1.00 65.17 C +ATOM 14602 OG SER H 167 58.512 -10.500 11.470 1.00 70.05 O +ATOM 14603 N THR H 168 54.227 -11.918 10.854 1.00118.43 N +ATOM 14604 CA THR H 168 52.922 -12.038 10.168 1.00101.48 C +ATOM 14605 C THR H 168 51.918 -13.010 10.818 1.00 88.08 C +ATOM 14606 O THR H 168 50.698 -12.846 10.715 1.00100.24 O +ATOM 14607 CB THR H 168 53.157 -12.479 8.721 1.00 88.75 C +ATOM 14608 OG1 THR H 168 53.989 -13.635 8.731 1.00 55.55 O +ATOM 14609 CG2 THR H 168 53.823 -11.349 7.933 1.00100.99 C +ATOM 14610 N GLY H 169 52.426 -14.067 11.423 1.00 76.53 N +ATOM 14611 CA GLY H 169 51.566 -15.133 11.853 1.00 78.57 C +ATOM 14612 C GLY H 169 51.428 -16.215 10.802 1.00 88.76 C +ATOM 14613 O GLY H 169 50.861 -17.280 11.080 1.00125.44 O +ATOM 14614 N GLU H 170 51.909 -15.952 9.581 1.00 82.30 N +ATOM 14615 CA GLU H 170 52.002 -17.009 8.543 1.00 71.95 C +ATOM 14616 C GLU H 170 52.794 -18.150 9.136 1.00 62.70 C +ATOM 14617 O GLU H 170 53.867 -17.941 9.695 1.00 63.17 O +ATOM 14618 CB GLU H 170 52.699 -16.508 7.259 1.00 72.52 C +ATOM 14619 CG GLU H 170 51.837 -15.650 6.342 1.00 76.07 C +ATOM 14620 CD GLU H 170 52.579 -14.504 5.652 1.00 77.30 C +ATOM 14621 OE1 GLU H 170 53.710 -14.191 6.058 1.00 78.41 O +ATOM 14622 OE2 GLU H 170 51.983 -13.826 4.796 1.00 56.94 O +ATOM 14623 N ILE H 171 52.240 -19.348 9.088 1.00 60.41 N +ATOM 14624 CA ILE H 171 53.049 -20.507 9.323 1.00 81.94 C +ATOM 14625 C ILE H 171 54.006 -20.655 8.131 1.00 98.74 C +ATOM 14626 O ILE H 171 53.558 -20.715 6.992 1.00 99.16 O +ATOM 14627 CB ILE H 171 52.173 -21.753 9.485 1.00 80.03 C +ATOM 14628 CG1 ILE H 171 51.451 -21.663 10.821 1.00 97.26 C +ATOM 14629 CG2 ILE H 171 53.039 -23.002 9.426 1.00 91.10 C +ATOM 14630 CD1 ILE H 171 50.298 -22.626 10.930 1.00101.33 C +ATOM 14631 N LEU H 172 55.314 -20.702 8.392 1.00 89.12 N +ATOM 14632 CA LEU H 172 56.280 -20.813 7.311 1.00 77.41 C +ATOM 14633 C LEU H 172 56.621 -22.283 6.950 1.00100.43 C +ATOM 14634 O LEU H 172 57.284 -22.572 5.930 1.00 91.87 O +ATOM 14635 CB LEU H 172 57.557 -20.026 7.640 1.00 72.00 C +ATOM 14636 CG LEU H 172 57.663 -18.540 7.244 1.00 73.00 C +ATOM 14637 CD1 LEU H 172 56.277 -17.979 7.192 1.00 69.41 C +ATOM 14638 CD2 LEU H 172 58.614 -17.679 8.056 1.00 93.95 C +ATOM 14639 N SER H 173 56.222 -23.213 7.818 1.00 88.54 N +ATOM 14640 CA SER H 173 56.514 -24.640 7.608 1.00 62.68 C +ATOM 14641 C SER H 173 55.831 -25.501 8.644 1.00 64.66 C +ATOM 14642 O SER H 173 55.888 -25.224 9.856 1.00113.24 O +ATOM 14643 CB SER H 173 58.015 -24.903 7.721 1.00 73.20 C +ATOM 14644 OG SER H 173 58.267 -26.284 7.877 1.00 70.39 O +ATOM 14645 N SER H 174 55.194 -26.556 8.190 1.00 72.60 N +ATOM 14646 CA SER H 174 54.637 -27.552 9.109 1.00 86.73 C +ATOM 14647 C SER H 174 55.203 -28.877 8.701 1.00102.78 C +ATOM 14648 O SER H 174 55.236 -29.208 7.506 1.00150.25 O +ATOM 14649 CB SER H 174 53.082 -27.600 9.060 1.00 93.14 C +ATOM 14650 OG SER H 174 52.523 -28.415 10.088 1.00 67.06 O +ATOM 14651 N VAL H 175 55.598 -29.665 9.688 1.00100.87 N +ATOM 14652 CA VAL H 175 56.103 -31.006 9.427 1.00103.59 C +ATOM 14653 C VAL H 175 55.517 -32.022 10.391 1.00103.91 C +ATOM 14654 O VAL H 175 55.339 -31.736 11.588 1.00169.21 O +ATOM 14655 CB VAL H 175 57.648 -31.038 9.497 1.00115.14 C +ATOM 14656 CG1 VAL H 175 58.244 -30.155 8.412 1.00110.74 C +ATOM 14657 CG2 VAL H 175 58.149 -30.577 10.849 1.00136.35 C +ATOM 14658 N ASN H 176 55.289 -33.228 9.882 1.00100.83 N +ATOM 14659 CA ASN H 176 54.684 -34.306 10.665 1.00133.19 C +ATOM 14660 C ASN H 176 55.529 -35.599 10.724 1.00131.07 C +ATOM 14661 O ASN H 176 55.402 -36.435 9.847 1.00118.98 O +ATOM 14662 CB ASN H 176 53.310 -34.592 10.055 1.00122.64 C +ATOM 14663 CG ASN H 176 52.190 -33.864 10.796 1.00110.73 C +ATOM 14664 OD1 ASN H 176 52.485 -32.935 11.537 1.00120.16 O +ATOM 14665 ND2 ASN H 176 50.915 -34.232 10.567 1.00105.07 N +ATOM 14666 N THR H 177 56.319 -35.784 11.789 1.00108.98 N +ATOM 14667 CA THR H 177 57.185 -36.953 11.904 1.00 84.87 C +ATOM 14668 C THR H 177 56.580 -38.032 12.781 1.00 86.63 C +ATOM 14669 O THR H 177 55.638 -37.778 13.532 1.00114.82 O +ATOM 14670 CB THR H 177 58.548 -36.588 12.495 1.00 96.52 C +ATOM 14671 OG1 THR H 177 58.413 -36.248 13.877 1.00 90.21 O +ATOM 14672 CG2 THR H 177 59.183 -35.403 11.743 1.00 97.52 C +ATOM 14673 N SER H 178 57.077 -39.253 12.624 1.00 92.91 N +ATOM 14674 CA SER H 178 56.489 -40.421 13.275 1.00 99.16 C +ATOM 14675 C SER H 178 57.558 -41.435 13.590 1.00 92.24 C +ATOM 14676 O SER H 178 58.571 -41.553 12.894 1.00 80.02 O +ATOM 14677 CB SER H 178 55.404 -41.083 12.397 1.00108.76 C +ATOM 14678 OG SER H 178 55.058 -42.374 12.887 1.00102.19 O +ATOM 14679 N LYS H 179 57.306 -42.225 14.616 1.00109.99 N +ATOM 14680 CA LYS H 179 58.311 -43.168 15.068 1.00125.47 C +ATOM 14681 C LYS H 179 57.668 -44.337 15.797 1.00104.81 C +ATOM 14682 O LYS H 179 56.642 -44.205 16.468 1.00157.70 O +ATOM 14683 CB LYS H 179 59.288 -42.439 15.985 1.00159.17 C +ATOM 14684 CG LYS H 179 60.729 -42.902 15.876 1.00164.79 C +ATOM 14685 CD LYS H 179 61.032 -43.947 16.931 1.00129.78 C +ATOM 14686 CE LYS H 179 62.409 -44.525 16.716 1.00113.43 C +ATOM 14687 NZ LYS H 179 62.605 -45.745 17.530 1.00101.89 N +ATOM 14688 N THR H 180 58.293 -45.486 15.670 1.00 60.09 N +ATOM 14689 CA THR H 180 57.751 -46.681 16.201 1.00 73.50 C +ATOM 14690 C THR H 180 58.529 -47.143 17.424 1.00 83.29 C +ATOM 14691 O THR H 180 59.749 -47.271 17.373 1.00 83.57 O +ATOM 14692 CB THR H 180 57.968 -47.791 15.166 1.00 86.84 C +ATOM 14693 OG1 THR H 180 57.607 -47.308 13.874 1.00 58.91 O +ATOM 14694 CG2 THR H 180 57.198 -49.064 15.504 1.00 81.69 C +ATOM 14695 N ILE H 181 57.799 -47.557 18.455 1.00 99.57 N +ATOM 14696 CA ILE H 181 58.404 -48.091 19.676 1.00 97.97 C +ATOM 14697 C ILE H 181 58.309 -49.630 19.688 1.00 87.71 C +ATOM 14698 O ILE H 181 57.216 -50.191 19.755 1.00 86.48 O +ATOM 14699 CB ILE H 181 57.735 -47.473 20.952 1.00 93.46 C +ATOM 14700 CG1 ILE H 181 57.715 -45.944 20.860 1.00 83.89 C +ATOM 14701 CG2 ILE H 181 58.460 -47.879 22.223 1.00 86.11 C +ATOM 14702 CD1 ILE H 181 56.324 -45.353 20.871 1.00 82.89 C +ATOM 14703 N LEU H 182 59.466 -50.282 19.678 1.00 84.55 N +ATOM 14704 CA LEU H 182 59.546 -51.737 19.695 1.00103.08 C +ATOM 14705 C LEU H 182 59.623 -52.368 21.092 1.00106.22 C +ATOM 14706 O LEU H 182 60.372 -51.909 21.966 1.00 97.93 O +ATOM 14707 CB LEU H 182 60.765 -52.183 18.887 1.00110.28 C +ATOM 14708 CG LEU H 182 60.997 -53.700 18.800 1.00 94.04 C +ATOM 14709 CD1 LEU H 182 59.853 -54.434 18.120 1.00 96.39 C +ATOM 14710 CD2 LEU H 182 62.303 -53.917 18.066 1.00 93.08 C +ATOM 14711 N SER H 183 58.923 -53.487 21.249 1.00131.89 N +ATOM 14712 CA SER H 183 59.002 -54.296 22.460 1.00155.39 C +ATOM 14713 C SER H 183 59.017 -55.780 22.096 1.00161.43 C +ATOM 14714 O SER H 183 58.294 -56.210 21.198 1.00165.30 O +ATOM 14715 CB SER H 183 57.812 -53.992 23.381 1.00135.92 C +ATOM 14716 OG SER H 183 57.499 -52.608 23.351 1.00152.40 O +ATOM 14717 N TYR H 184 59.819 -56.563 22.814 1.00176.70 N +ATOM 14718 CA TYR H 184 59.841 -58.015 22.620 1.00157.04 C +ATOM 14719 C TYR H 184 60.243 -58.824 23.861 1.00135.77 C +ATOM 14720 O TYR H 184 60.924 -58.337 24.773 1.00126.95 O +ATOM 14721 CB TYR H 184 60.734 -58.394 21.432 1.00145.32 C +ATOM 14722 CG TYR H 184 62.177 -57.957 21.562 1.00138.57 C +ATOM 14723 CD1 TYR H 184 63.109 -58.724 22.271 1.00 90.87 C +ATOM 14724 CD2 TYR H 184 62.613 -56.780 20.968 1.00133.74 C +ATOM 14725 CE1 TYR H 184 64.422 -58.329 22.379 1.00 69.26 C +ATOM 14726 CE2 TYR H 184 63.930 -56.383 21.075 1.00117.25 C +ATOM 14727 CZ TYR H 184 64.831 -57.173 21.763 1.00 84.52 C +ATOM 14728 OH TYR H 184 66.112 -56.706 21.946 1.00106.96 O +ATOM 14729 N GLU H 185 59.777 -60.066 23.875 1.00136.55 N +ATOM 14730 CA GLU H 185 59.982 -60.988 24.990 1.00170.80 C +ATOM 14731 C GLU H 185 60.432 -62.337 24.469 1.00200.30 C +ATOM 14732 O GLU H 185 59.654 -63.046 23.835 1.00250.92 O +ATOM 14733 CB GLU H 185 58.718 -61.201 25.840 1.00165.45 C +ATOM 14734 CG GLU H 185 57.905 -59.962 26.153 1.00171.55 C +ATOM 14735 CD GLU H 185 56.817 -60.256 27.177 1.00167.30 C +ATOM 14736 OE1 GLU H 185 56.671 -61.431 27.581 1.00145.48 O +ATOM 14737 OE2 GLU H 185 56.105 -59.311 27.568 1.00148.89 O +ATOM 14738 N VAL H 186 61.679 -62.686 24.766 1.00197.22 N +ATOM 14739 CA VAL H 186 62.239 -63.981 24.407 1.00163.42 C +ATOM 14740 C VAL H 186 62.279 -64.890 25.633 1.00141.02 C +ATOM 14741 O VAL H 186 62.574 -64.442 26.741 1.00142.07 O +ATOM 14742 CB VAL H 186 63.661 -63.831 23.848 1.00144.18 C +ATOM 14743 CG1 VAL H 186 64.146 -65.157 23.288 1.00139.86 C +ATOM 14744 CG2 VAL H 186 63.694 -62.753 22.777 1.00138.89 C +ATOM 14745 N GLN H 187 61.937 -66.157 25.436 1.00123.85 N +ATOM 14746 CA GLN H 187 61.816 -67.084 26.547 1.00151.63 C +ATOM 14747 C GLN H 187 62.178 -68.477 26.114 1.00164.93 C +ATOM 14748 O GLN H 187 61.737 -68.931 25.058 1.00240.64 O +ATOM 14749 CB GLN H 187 60.376 -67.091 27.085 1.00154.47 C +ATOM 14750 CG GLN H 187 60.059 -66.021 28.101 1.00157.94 C +ATOM 14751 CD GLN H 187 58.577 -65.738 28.132 1.00172.28 C +ATOM 14752 OE1 GLN H 187 58.171 -64.624 28.431 1.00202.30 O +ATOM 14753 NE2 GLN H 187 57.759 -66.737 27.771 1.00169.30 N +ATOM 14754 N ALA H 188 62.906 -69.180 26.973 1.00170.75 N +ATOM 14755 CA ALA H 188 63.225 -70.576 26.716 1.00149.77 C +ATOM 14756 C ALA H 188 63.166 -71.388 28.010 1.00148.76 C +ATOM 14757 O ALA H 188 63.535 -70.899 29.070 1.00142.37 O +ATOM 14758 CB ALA H 188 64.593 -70.679 26.067 1.00116.88 C +ATOM 14759 N GLY H 189 62.647 -72.605 27.927 1.00146.89 N +ATOM 14760 CA GLY H 189 62.537 -73.468 29.089 1.00157.29 C +ATOM 14761 C GLY H 189 62.794 -74.921 28.753 1.00193.08 C +ATOM 14762 O GLY H 189 62.329 -75.422 27.732 1.00204.98 O +ATOM 14763 N VAL H 190 63.536 -75.599 29.622 1.00225.18 N +ATOM 14764 CA VAL H 190 63.801 -77.023 29.469 1.00209.43 C +ATOM 14765 C VAL H 190 63.138 -77.802 30.617 1.00214.82 C +ATOM 14766 O VAL H 190 63.222 -77.395 31.784 1.00232.65 O +ATOM 14767 CB VAL H 190 65.320 -77.299 29.440 1.00171.58 C +ATOM 14768 CG1 VAL H 190 65.578 -78.734 29.029 1.00172.83 C +ATOM 14769 CG2 VAL H 190 66.035 -76.321 28.508 1.00133.12 C +ATOM 14770 N PHE H 191 62.478 -78.910 30.282 1.00202.08 N +ATOM 14771 CA PHE H 191 61.648 -79.644 31.248 1.00212.72 C +ATOM 14772 C PHE H 191 61.883 -81.172 31.124 1.00261.31 C +ATOM 14773 O PHE H 191 61.944 -81.692 30.041 1.00299.14 O +ATOM 14774 CB PHE H 191 60.167 -79.334 30.975 1.00175.87 C +ATOM 14775 CG PHE H 191 59.255 -79.604 32.146 1.00178.75 C +ATOM 14776 CD1 PHE H 191 58.939 -80.910 32.520 1.00140.81 C +ATOM 14777 CD2 PHE H 191 58.687 -78.557 32.852 1.00202.15 C +ATOM 14778 CE1 PHE H 191 58.111 -81.164 33.594 1.00118.00 C +ATOM 14779 CE2 PHE H 191 57.821 -78.808 33.907 1.00194.35 C +ATOM 14780 CZ PHE H 191 57.541 -80.113 34.282 1.00152.57 C +ATOM 14781 N ARG H 192 61.948 -81.905 32.233 1.00251.60 N +ATOM 14782 CA ARG H 192 62.089 -83.375 32.187 1.00193.49 C +ATOM 14783 C ARG H 192 61.627 -84.011 33.505 1.00159.62 C +ATOM 14784 O ARG H 192 61.373 -85.210 33.581 1.00110.71 O +ATOM 14785 CB ARG H 192 63.544 -83.757 31.867 1.00171.43 C +ATOM 14786 CG ARG H 192 63.793 -84.180 30.422 1.00154.84 C +ATOM 14787 CD ARG H 192 65.142 -83.712 29.904 1.00158.11 C +ATOM 14788 NE ARG H 192 65.222 -83.754 28.447 1.00169.31 N +ATOM 14789 CZ ARG H 192 65.749 -82.807 27.671 1.00144.24 C +ATOM 14790 NH1 ARG H 192 66.202 -81.681 28.200 1.00142.02 N +ATOM 14791 NH2 ARG H 192 65.876 -83.015 26.365 1.00113.99 N +ATOM 14792 N LEU H 200 63.775 -82.185 36.607 1.00 88.13 N +ATOM 14793 CA LEU H 200 64.537 -81.087 36.023 1.00138.98 C +ATOM 14794 C LEU H 200 63.631 -80.101 35.296 1.00173.64 C +ATOM 14795 O LEU H 200 63.079 -80.409 34.230 1.00196.86 O +ATOM 14796 CB LEU H 200 65.617 -81.572 35.036 1.00149.84 C +ATOM 14797 CG LEU H 200 66.328 -80.440 34.249 1.00147.62 C +ATOM 14798 CD1 LEU H 200 67.686 -80.143 34.873 1.00135.71 C +ATOM 14799 CD2 LEU H 200 66.456 -80.727 32.749 1.00124.28 C +ATOM 14800 N GLU H 201 63.532 -78.895 35.843 1.00195.51 N +ATOM 14801 CA GLU H 201 63.062 -77.747 35.080 1.00207.55 C +ATOM 14802 C GLU H 201 64.131 -76.664 35.057 1.00207.67 C +ATOM 14803 O GLU H 201 64.895 -76.511 36.011 1.00177.64 O +ATOM 14804 CB GLU H 201 61.777 -77.185 35.681 1.00216.54 C +ATOM 14805 CG GLU H 201 61.002 -76.307 34.710 1.00211.54 C +ATOM 14806 CD GLU H 201 59.720 -75.743 35.307 1.00217.59 C +ATOM 14807 OE1 GLU H 201 58.913 -76.526 35.861 1.00260.46 O +ATOM 14808 OE2 GLU H 201 59.489 -74.526 35.182 1.00185.23 O +ATOM 14809 N GLY H 202 64.185 -75.914 33.959 1.00224.62 N +ATOM 14810 CA GLY H 202 65.074 -74.757 33.861 1.00227.31 C +ATOM 14811 C GLY H 202 64.551 -73.728 32.879 1.00218.67 C +ATOM 14812 O GLY H 202 64.240 -74.059 31.735 1.00241.83 O +ATOM 14813 N GLU H 203 64.420 -72.484 33.331 1.00199.70 N +ATOM 14814 CA GLU H 203 63.830 -71.440 32.502 1.00172.67 C +ATOM 14815 C GLU H 203 64.675 -70.172 32.442 1.00142.75 C +ATOM 14816 O GLU H 203 65.173 -69.685 33.457 1.00108.21 O +ATOM 14817 CB GLU H 203 62.424 -71.102 32.994 1.00182.62 C +ATOM 14818 CG GLU H 203 61.425 -72.247 32.812 1.00189.81 C +ATOM 14819 CD GLU H 203 59.992 -71.900 33.202 1.00197.49 C +ATOM 14820 OE1 GLU H 203 59.773 -70.807 33.767 1.00173.72 O +ATOM 14821 OE2 GLU H 203 59.088 -72.728 32.946 1.00198.28 O +ATOM 14822 N VAL H 204 64.824 -69.657 31.228 1.00130.51 N +ATOM 14823 CA VAL H 204 65.488 -68.388 30.989 1.00140.15 C +ATOM 14824 C VAL H 204 64.527 -67.479 30.239 1.00164.03 C +ATOM 14825 O VAL H 204 63.843 -67.906 29.300 1.00198.35 O +ATOM 14826 CB VAL H 204 66.791 -68.584 30.183 1.00138.22 C +ATOM 14827 CG1 VAL H 204 67.290 -67.268 29.586 1.00149.57 C +ATOM 14828 CG2 VAL H 204 67.857 -69.212 31.073 1.00124.90 C +ATOM 14829 N GLY H 205 64.467 -66.222 30.667 1.00183.39 N +ATOM 14830 CA GLY H 205 63.645 -65.225 29.999 1.00183.82 C +ATOM 14831 C GLY H 205 64.355 -63.889 29.837 1.00175.71 C +ATOM 14832 O GLY H 205 65.223 -63.532 30.638 1.00138.03 O +ATOM 14833 N TYR H 206 63.986 -63.151 28.792 1.00167.41 N +ATOM 14834 CA TYR H 206 64.486 -61.791 28.589 1.00141.85 C +ATOM 14835 C TYR H 206 63.418 -60.941 27.916 1.00160.96 C +ATOM 14836 O TYR H 206 62.710 -61.420 27.039 1.00190.10 O +ATOM 14837 CB TYR H 206 65.737 -61.805 27.720 1.00128.90 C +ATOM 14838 CG TYR H 206 66.268 -60.422 27.406 1.00128.49 C +ATOM 14839 CD1 TYR H 206 66.958 -59.670 28.374 1.00104.00 C +ATOM 14840 CD2 TYR H 206 66.085 -59.868 26.138 1.00134.87 C +ATOM 14841 CE1 TYR H 206 67.487 -58.429 28.073 1.00101.72 C +ATOM 14842 CE2 TYR H 206 66.602 -58.625 25.831 1.00140.57 C +ATOM 14843 CZ TYR H 206 67.300 -57.914 26.798 1.00138.03 C +ATOM 14844 OH TYR H 206 67.748 -56.656 26.477 1.00193.91 O +ATOM 14845 N THR H 207 63.311 -59.677 28.318 1.00173.17 N +ATOM 14846 CA THR H 207 62.342 -58.758 27.714 1.00151.16 C +ATOM 14847 C THR H 207 62.954 -57.371 27.480 1.00128.64 C +ATOM 14848 O THR H 207 63.685 -56.850 28.335 1.00109.94 O +ATOM 14849 CB THR H 207 61.087 -58.600 28.599 1.00149.48 C +ATOM 14850 OG1 THR H 207 61.460 -58.047 29.866 1.00141.55 O +ATOM 14851 CG2 THR H 207 60.412 -59.933 28.831 1.00143.80 C +ATOM 14852 N SER H 208 62.672 -56.784 26.319 1.00107.54 N +ATOM 14853 CA SER H 208 63.211 -55.460 26.001 1.00118.16 C +ATOM 14854 C SER H 208 62.154 -54.531 25.430 1.00123.29 C +ATOM 14855 O SER H 208 61.500 -54.859 24.445 1.00116.15 O +ATOM 14856 CB SER H 208 64.393 -55.551 25.030 1.00120.23 C +ATOM 14857 OG SER H 208 64.814 -54.259 24.597 1.00111.75 O +ATOM 14858 N ASN H 209 62.029 -53.362 26.056 1.00147.28 N +ATOM 14859 CA ASN H 209 61.187 -52.269 25.573 1.00122.76 C +ATOM 14860 C ASN H 209 62.026 -51.083 25.165 1.00109.41 C +ATOM 14861 O ASN H 209 62.986 -50.724 25.861 1.00159.08 O +ATOM 14862 CB ASN H 209 60.242 -51.798 26.668 1.00 99.91 C +ATOM 14863 CG ASN H 209 59.188 -52.823 26.993 1.00 94.57 C +ATOM 14864 OD1 ASN H 209 58.171 -52.918 26.310 1.00128.77 O +ATOM 14865 ND2 ASN H 209 59.417 -53.584 28.033 1.00 74.65 N +ATOM 14866 N GLU H 210 61.703 -50.510 24.018 1.00 83.14 N +ATOM 14867 CA GLU H 210 62.307 -49.245 23.651 1.00 89.06 C +ATOM 14868 C GLU H 210 61.791 -48.207 24.619 1.00 99.94 C +ATOM 14869 O GLU H 210 60.626 -48.240 25.026 1.00117.06 O +ATOM 14870 CB GLU H 210 61.938 -48.868 22.224 1.00 91.20 C +ATOM 14871 CG GLU H 210 63.069 -48.307 21.391 1.00100.68 C +ATOM 14872 CD GLU H 210 62.759 -48.348 19.894 1.00143.78 C +ATOM 14873 OE1 GLU H 210 61.971 -49.222 19.416 1.00159.92 O +ATOM 14874 OE2 GLU H 210 63.344 -47.517 19.169 1.00198.04 O +ATOM 14875 N PRO H 211 62.651 -47.265 25.001 1.00123.92 N +ATOM 14876 CA PRO H 211 62.148 -46.133 25.772 1.00155.50 C +ATOM 14877 C PRO H 211 61.321 -45.157 24.918 1.00157.60 C +ATOM 14878 O PRO H 211 61.796 -44.686 23.882 1.00111.96 O +ATOM 14879 CB PRO H 211 63.429 -45.458 26.285 1.00161.21 C +ATOM 14880 CG PRO H 211 64.504 -46.481 26.133 1.00130.89 C +ATOM 14881 CD PRO H 211 64.114 -47.256 24.917 1.00128.36 C +ATOM 14882 N VAL H 212 60.099 -44.866 25.369 1.00134.42 N +ATOM 14883 CA VAL H 212 59.203 -43.959 24.661 1.00111.10 C +ATOM 14884 C VAL H 212 59.823 -42.580 24.684 1.00105.50 C +ATOM 14885 O VAL H 212 59.801 -41.833 23.703 1.00109.01 O +ATOM 14886 CB VAL H 212 57.822 -43.902 25.337 1.00 99.95 C +ATOM 14887 CG1 VAL H 212 56.875 -43.040 24.504 1.00102.18 C +ATOM 14888 CG2 VAL H 212 57.235 -45.306 25.520 1.00119.86 C +ATOM 14889 N MET H 213 60.367 -42.258 25.849 1.00111.90 N +ATOM 14890 CA MET H 213 61.289 -41.129 26.075 1.00121.15 C +ATOM 14891 C MET H 213 62.267 -40.848 24.914 1.00 90.13 C +ATOM 14892 O MET H 213 62.354 -39.741 24.383 1.00 56.80 O +ATOM 14893 CB MET H 213 62.060 -41.522 27.334 1.00156.91 C +ATOM 14894 CG MET H 213 63.029 -40.532 27.908 1.00212.84 C +ATOM 14895 SD MET H 213 63.752 -41.352 29.365 1.00228.28 S +ATOM 14896 CE MET H 213 65.391 -41.541 28.695 1.00252.37 C +ATOM 14897 N LEU H 214 62.890 -41.912 24.452 1.00 96.46 N +ATOM 14898 CA LEU H 214 64.015 -41.806 23.558 1.00119.04 C +ATOM 14899 C LEU H 214 63.487 -41.689 22.148 1.00101.51 C +ATOM 14900 O LEU H 214 64.146 -41.137 21.267 1.00109.04 O +ATOM 14901 CB LEU H 214 64.935 -43.043 23.732 1.00171.55 C +ATOM 14902 CG LEU H 214 66.457 -42.855 23.764 1.00186.51 C +ATOM 14903 CD1 LEU H 214 66.897 -41.923 24.896 1.00210.03 C +ATOM 14904 CD2 LEU H 214 67.155 -44.206 23.894 1.00159.66 C +ATOM 14905 N CYS H 215 62.336 -42.311 21.911 1.00105.50 N +ATOM 14906 CA CYS H 215 61.710 -42.289 20.587 1.00132.66 C +ATOM 14907 C CYS H 215 61.144 -40.903 20.315 1.00153.38 C +ATOM 14908 O CYS H 215 61.225 -40.373 19.185 1.00163.79 O +ATOM 14909 CB CYS H 215 60.579 -43.311 20.511 1.00119.46 C +ATOM 14910 SG CYS H 215 61.121 -45.019 20.631 1.00101.18 S +ATOM 14911 N LEU H 216 60.543 -40.330 21.354 1.00137.10 N +ATOM 14912 CA LEU H 216 60.063 -38.965 21.278 1.00124.49 C +ATOM 14913 C LEU H 216 61.221 -38.045 20.911 1.00125.87 C +ATOM 14914 O LEU H 216 61.113 -37.235 19.977 1.00122.29 O +ATOM 14915 CB LEU H 216 59.445 -38.537 22.600 1.00111.90 C +ATOM 14916 CG LEU H 216 58.954 -37.085 22.637 1.00 96.43 C +ATOM 14917 CD1 LEU H 216 57.926 -36.785 21.566 1.00 89.24 C +ATOM 14918 CD2 LEU H 216 58.370 -36.787 24.013 1.00114.40 C +ATOM 14919 N MET H 217 62.353 -38.232 21.593 1.00 98.44 N +ATOM 14920 CA MET H 217 63.498 -37.360 21.383 1.00117.13 C +ATOM 14921 C MET H 217 64.011 -37.489 19.954 1.00113.52 C +ATOM 14922 O MET H 217 64.218 -36.487 19.262 1.00 91.11 O +ATOM 14923 CB MET H 217 64.608 -37.671 22.385 1.00135.62 C +ATOM 14924 CG MET H 217 65.258 -36.422 22.974 1.00135.85 C +ATOM 14925 SD MET H 217 66.240 -35.514 21.765 1.00139.52 S +ATOM 14926 CE MET H 217 66.620 -33.998 22.643 1.00164.96 C +ATOM 14927 N SER H 218 64.146 -38.731 19.499 1.00115.69 N +ATOM 14928 CA SER H 218 64.581 -39.022 18.135 1.00135.90 C +ATOM 14929 C SER H 218 63.688 -38.325 17.090 1.00149.49 C +ATOM 14930 O SER H 218 64.183 -37.656 16.173 1.00138.28 O +ATOM 14931 CB SER H 218 64.577 -40.540 17.896 1.00122.90 C +ATOM 14932 OG SER H 218 65.210 -40.867 16.671 1.00138.97 O +ATOM 14933 N ALA H 219 62.379 -38.505 17.227 1.00119.36 N +ATOM 14934 CA ALA H 219 61.445 -37.993 16.252 1.00107.87 C +ATOM 14935 C ALA H 219 61.478 -36.452 16.207 1.00124.53 C +ATOM 14936 O ALA H 219 61.297 -35.828 15.146 1.00110.34 O +ATOM 14937 CB ALA H 219 60.055 -38.503 16.579 1.00112.34 C +ATOM 14938 N ILE H 220 61.682 -35.825 17.361 1.00123.29 N +ATOM 14939 CA ILE H 220 61.745 -34.361 17.415 1.00118.46 C +ATOM 14940 C ILE H 220 62.985 -33.849 16.667 1.00128.81 C +ATOM 14941 O ILE H 220 62.923 -32.853 15.947 1.00 74.81 O +ATOM 14942 CB ILE H 220 61.737 -33.849 18.874 1.00120.82 C +ATOM 14943 CG1 ILE H 220 60.356 -34.107 19.503 1.00 99.69 C +ATOM 14944 CG2 ILE H 220 62.116 -32.356 18.930 1.00102.70 C +ATOM 14945 CD1 ILE H 220 60.332 -34.019 21.011 1.00 98.94 C +ATOM 14946 N GLU H 221 64.111 -34.546 16.840 1.00134.57 N +ATOM 14947 CA GLU H 221 65.347 -34.204 16.126 1.00108.22 C +ATOM 14948 C GLU H 221 65.107 -34.248 14.621 1.00118.27 C +ATOM 14949 O GLU H 221 65.404 -33.289 13.895 1.00 81.31 O +ATOM 14950 CB GLU H 221 66.466 -35.171 16.519 1.00 85.54 C +ATOM 14951 CG GLU H 221 67.032 -34.920 17.909 1.00 83.46 C +ATOM 14952 CD GLU H 221 67.811 -36.098 18.490 1.00 81.55 C +ATOM 14953 OE1 GLU H 221 67.470 -37.284 18.224 1.00 53.27 O +ATOM 14954 OE2 GLU H 221 68.823 -35.815 19.179 1.00 83.79 O +ATOM 14955 N THR H 222 64.543 -35.371 14.175 1.00135.30 N +ATOM 14956 CA THR H 222 64.191 -35.591 12.772 1.00126.86 C +ATOM 14957 C THR H 222 63.360 -34.432 12.245 1.00111.94 C +ATOM 14958 O THR H 222 63.619 -33.908 11.157 1.00 88.89 O +ATOM 14959 CB THR H 222 63.387 -36.907 12.622 1.00113.70 C +ATOM 14960 OG1 THR H 222 64.249 -38.040 12.828 1.00106.32 O +ATOM 14961 CG2 THR H 222 62.703 -36.982 11.242 1.00111.26 C +ATOM 14962 N GLY H 223 62.337 -34.066 13.015 1.00103.66 N +ATOM 14963 CA GLY H 223 61.483 -32.941 12.667 1.00128.48 C +ATOM 14964 C GLY H 223 62.280 -31.656 12.483 1.00122.21 C +ATOM 14965 O GLY H 223 61.976 -30.852 11.581 1.00 88.33 O +ATOM 14966 N VAL H 224 63.264 -31.435 13.355 1.00106.12 N +ATOM 14967 CA VAL H 224 64.043 -30.205 13.300 1.00128.08 C +ATOM 14968 C VAL H 224 64.830 -30.176 12.001 1.00141.00 C +ATOM 14969 O VAL H 224 64.907 -29.139 11.334 1.00142.20 O +ATOM 14970 CB VAL H 224 65.010 -30.083 14.481 1.00131.69 C +ATOM 14971 CG1 VAL H 224 65.945 -28.899 14.273 1.00119.27 C +ATOM 14972 CG2 VAL H 224 64.235 -29.936 15.783 1.00148.36 C +ATOM 14973 N ILE H 225 65.365 -31.329 11.611 1.00137.49 N +ATOM 14974 CA ILE H 225 66.102 -31.417 10.353 1.00125.92 C +ATOM 14975 C ILE H 225 65.192 -31.065 9.182 1.00121.03 C +ATOM 14976 O ILE H 225 65.547 -30.208 8.372 1.00 95.92 O +ATOM 14977 CB ILE H 225 66.730 -32.810 10.134 1.00114.55 C +ATOM 14978 CG1 ILE H 225 67.844 -33.045 11.156 1.00123.50 C +ATOM 14979 CG2 ILE H 225 67.313 -32.920 8.727 1.00 93.35 C +ATOM 14980 CD1 ILE H 225 68.230 -34.499 11.319 1.00117.41 C +ATOM 14981 N PHE H 226 64.028 -31.721 9.104 1.00111.06 N +ATOM 14982 CA PHE H 226 63.067 -31.471 8.018 1.00111.53 C +ATOM 14983 C PHE H 226 62.667 -29.997 7.961 1.00115.59 C +ATOM 14984 O PHE H 226 62.421 -29.450 6.888 1.00118.79 O +ATOM 14985 CB PHE H 226 61.807 -32.342 8.166 1.00103.75 C +ATOM 14986 CG PHE H 226 61.961 -33.762 7.672 1.00 96.97 C +ATOM 14987 CD1 PHE H 226 62.262 -34.021 6.339 1.00107.79 C +ATOM 14988 CD2 PHE H 226 61.711 -34.844 8.516 1.00 93.31 C +ATOM 14989 CE1 PHE H 226 62.403 -35.329 5.880 1.00109.60 C +ATOM 14990 CE2 PHE H 226 61.820 -36.148 8.059 1.00 94.67 C +ATOM 14991 CZ PHE H 226 62.181 -36.392 6.742 1.00112.28 C +ATOM 14992 N LEU H 227 62.601 -29.360 9.121 1.00117.21 N +ATOM 14993 CA LEU H 227 62.293 -27.936 9.188 1.00126.34 C +ATOM 14994 C LEU H 227 63.404 -27.082 8.596 1.00118.38 C +ATOM 14995 O LEU H 227 63.135 -26.160 7.840 1.00 85.25 O +ATOM 14996 CB LEU H 227 62.051 -27.545 10.642 1.00139.25 C +ATOM 14997 CG LEU H 227 60.685 -27.934 11.233 1.00128.64 C +ATOM 14998 CD1 LEU H 227 60.576 -27.799 12.736 1.00121.78 C +ATOM 14999 CD2 LEU H 227 59.562 -27.155 10.582 1.00129.28 C +ATOM 15000 N ILE H 228 64.651 -27.405 8.932 1.00139.74 N +ATOM 15001 CA ILE H 228 65.794 -26.653 8.426 1.00134.72 C +ATOM 15002 C ILE H 228 65.879 -26.820 6.917 1.00138.39 C +ATOM 15003 O ILE H 228 66.043 -25.841 6.184 1.00131.24 O +ATOM 15004 CB ILE H 228 67.132 -27.104 9.053 1.00133.36 C +ATOM 15005 CG1 ILE H 228 67.147 -26.831 10.557 1.00158.80 C +ATOM 15006 CG2 ILE H 228 68.290 -26.353 8.418 1.00110.90 C +ATOM 15007 CD1 ILE H 228 68.240 -27.556 11.316 1.00153.22 C +ATOM 15008 N ASN H 229 65.771 -28.065 6.456 1.00135.07 N +ATOM 15009 CA ASN H 229 65.865 -28.370 5.029 1.00128.21 C +ATOM 15010 C ASN H 229 64.758 -27.664 4.251 1.00122.96 C +ATOM 15011 O ASN H 229 65.012 -27.031 3.219 1.00 87.73 O +ATOM 15012 CB ASN H 229 65.788 -29.885 4.816 1.00117.95 C +ATOM 15013 CG ASN H 229 66.284 -30.314 3.450 1.00160.25 C +ATOM 15014 OD1 ASN H 229 67.027 -29.590 2.780 1.00179.72 O +ATOM 15015 ND2 ASN H 229 65.827 -31.476 3.003 1.00181.40 N +ATOM 15016 N ASP H 230 63.551 -27.706 4.805 1.00126.13 N +ATOM 15017 CA ASP H 230 62.415 -27.027 4.213 1.00138.83 C +ATOM 15018 C ASP H 230 62.667 -25.521 4.130 1.00161.48 C +ATOM 15019 O ASP H 230 62.337 -24.867 3.137 1.00178.67 O +ATOM 15020 CB ASP H 230 61.156 -27.309 5.028 1.00136.89 C +ATOM 15021 CG ASP H 230 59.909 -26.753 4.375 1.00173.24 C +ATOM 15022 OD1 ASP H 230 59.479 -27.320 3.352 1.00216.25 O +ATOM 15023 OD2 ASP H 230 59.350 -25.745 4.866 1.00228.13 O +ATOM 15024 N GLY H 231 63.234 -24.961 5.192 1.00164.23 N +ATOM 15025 CA GLY H 231 63.519 -23.528 5.231 1.00175.95 C +ATOM 15026 C GLY H 231 64.591 -23.123 4.229 1.00167.35 C +ATOM 15027 O GLY H 231 64.549 -22.020 3.662 1.00104.00 O +ATOM 15028 N ILE H 232 65.563 -24.011 4.029 1.00167.02 N +ATOM 15029 CA ILE H 232 66.601 -23.793 3.031 1.00157.60 C +ATOM 15030 C ILE H 232 65.952 -23.687 1.662 1.00147.34 C +ATOM 15031 O ILE H 232 66.246 -22.746 0.910 1.00145.22 O +ATOM 15032 CB ILE H 232 67.654 -24.923 3.048 1.00154.60 C +ATOM 15033 CG1 ILE H 232 68.543 -24.780 4.287 1.00159.12 C +ATOM 15034 CG2 ILE H 232 68.505 -24.909 1.782 1.00171.42 C +ATOM 15035 CD1 ILE H 232 69.318 -26.034 4.639 1.00175.46 C +ATOM 15036 N ASP H 233 65.097 -24.662 1.342 1.00112.50 N +ATOM 15037 CA ASP H 233 64.406 -24.691 0.060 1.00117.79 C +ATOM 15038 C ASP H 233 63.600 -23.416 -0.149 1.00126.35 C +ATOM 15039 O ASP H 233 63.680 -22.778 -1.210 1.00174.06 O +ATOM 15040 CB ASP H 233 63.467 -25.903 -0.022 1.00120.19 C +ATOM 15041 CG ASP H 233 64.209 -27.246 -0.010 1.00113.02 C +ATOM 15042 OD1 ASP H 233 65.438 -27.255 0.178 1.00 84.86 O +ATOM 15043 OD2 ASP H 233 63.560 -28.279 -0.313 1.00118.06 O +ATOM 15044 N ARG H 234 62.838 -23.034 0.865 1.00128.57 N +ATOM 15045 CA ARG H 234 61.908 -21.909 0.745 1.00156.41 C +ATOM 15046 C ARG H 234 62.542 -20.520 0.942 1.00146.62 C +ATOM 15047 O ARG H 234 61.855 -19.495 0.824 1.00106.97 O +ATOM 15048 CB ARG H 234 60.757 -22.088 1.728 1.00167.94 C +ATOM 15049 CG ARG H 234 59.814 -23.183 1.300 1.00169.45 C +ATOM 15050 CD ARG H 234 59.004 -23.723 2.456 1.00168.81 C +ATOM 15051 NE ARG H 234 58.174 -24.814 1.971 1.00194.50 N +ATOM 15052 CZ ARG H 234 56.848 -24.832 2.027 1.00181.44 C +ATOM 15053 NH1 ARG H 234 56.187 -23.853 2.643 1.00124.97 N +ATOM 15054 NH2 ARG H 234 56.182 -25.864 1.499 1.00204.57 N +ATOM 15055 N GLY H 235 63.843 -20.487 1.219 1.00119.02 N +ATOM 15056 CA GLY H 235 64.563 -19.228 1.305 1.00118.06 C +ATOM 15057 C GLY H 235 64.296 -18.498 2.604 1.00114.34 C +ATOM 15058 O GLY H 235 64.312 -17.265 2.639 1.00 95.22 O +ATOM 15059 N LEU H 236 64.084 -19.250 3.686 1.00120.55 N +ATOM 15060 CA LEU H 236 64.068 -18.641 5.035 1.00118.01 C +ATOM 15061 C LEU H 236 65.497 -18.315 5.448 1.00128.76 C +ATOM 15062 O LEU H 236 65.789 -17.204 5.885 1.00112.01 O +ATOM 15063 CB LEU H 236 63.438 -19.570 6.084 1.00102.91 C +ATOM 15064 CG LEU H 236 61.919 -19.577 6.210 1.00 95.00 C +ATOM 15065 CD1 LEU H 236 61.286 -20.406 5.090 1.00117.40 C +ATOM 15066 CD2 LEU H 236 61.497 -20.128 7.560 1.00 81.06 C +ATOM 15067 N TRP H 237 66.389 -19.288 5.272 1.00129.96 N +ATOM 15068 CA TRP H 237 67.787 -19.132 5.655 1.00146.31 C +ATOM 15069 C TRP H 237 68.711 -19.767 4.611 1.00175.20 C +ATOM 15070 O TRP H 237 68.249 -20.524 3.751 1.00180.74 O +ATOM 15071 CB TRP H 237 68.023 -19.747 7.031 1.00135.17 C +ATOM 15072 CG TRP H 237 67.168 -20.931 7.287 1.00124.98 C +ATOM 15073 CD1 TRP H 237 67.261 -22.141 6.682 1.00155.66 C +ATOM 15074 CD2 TRP H 237 66.090 -21.033 8.225 1.00121.49 C +ATOM 15075 NE1 TRP H 237 66.317 -23.000 7.190 1.00172.58 N +ATOM 15076 CE2 TRP H 237 65.604 -22.354 8.161 1.00138.07 C +ATOM 15077 CE3 TRP H 237 65.515 -20.152 9.134 1.00142.62 C +ATOM 15078 CZ2 TRP H 237 64.552 -22.810 8.955 1.00140.84 C +ATOM 15079 CZ3 TRP H 237 64.461 -20.606 9.919 1.00170.29 C +ATOM 15080 CH2 TRP H 237 63.984 -21.919 9.811 1.00160.33 C +ATOM 15081 N ASP H 238 70.002 -19.426 4.673 1.00183.21 N +ATOM 15082 CA ASP H 238 70.958 -19.809 3.630 1.00159.70 C +ATOM 15083 C ASP H 238 72.207 -20.475 4.185 1.00168.08 C +ATOM 15084 O ASP H 238 72.675 -20.144 5.285 1.00180.97 O +ATOM 15085 CB ASP H 238 71.368 -18.599 2.791 1.00113.99 C +ATOM 15086 CG ASP H 238 70.181 -17.892 2.164 1.00124.26 C +ATOM 15087 OD1 ASP H 238 69.514 -17.126 2.868 1.00102.52 O +ATOM 15088 OD2 ASP H 238 69.886 -18.116 0.970 1.00165.71 O +ATOM 15089 N LEU H 239 72.750 -21.409 3.403 1.00147.07 N +ATOM 15090 CA LEU H 239 73.942 -22.142 3.797 1.00169.36 C +ATOM 15091 C LEU H 239 75.177 -21.259 3.647 1.00189.16 C +ATOM 15092 O LEU H 239 75.269 -20.455 2.716 1.00172.58 O +ATOM 15093 CB LEU H 239 74.102 -23.416 2.950 1.00166.54 C +ATOM 15094 CG LEU H 239 73.237 -24.642 3.247 1.00147.27 C +ATOM 15095 CD1 LEU H 239 73.634 -25.814 2.364 1.00157.11 C +ATOM 15096 CD2 LEU H 239 73.349 -25.036 4.703 1.00141.85 C +ATOM 15097 N GLN H 240 76.131 -21.438 4.559 1.00185.39 N +ATOM 15098 CA GLN H 240 77.463 -20.856 4.408 1.00168.26 C +ATOM 15099 C GLN H 240 78.074 -21.223 3.057 1.00176.26 C +ATOM 15100 O GLN H 240 78.407 -20.352 2.245 1.00142.75 O +ATOM 15101 CB GLN H 240 78.386 -21.333 5.541 1.00153.88 C +ATOM 15102 CG GLN H 240 79.725 -20.609 5.585 1.00145.62 C +ATOM 15103 CD GLN H 240 79.566 -19.130 5.906 1.00162.52 C +ATOM 15104 OE1 GLN H 240 79.394 -18.750 7.070 1.00180.73 O +ATOM 15105 NE2 GLN H 240 79.573 -18.289 4.871 1.00155.98 N +ATOM 15106 N ASN H 241 78.175 -22.526 2.818 1.00197.67 N +ATOM 15107 CA ASN H 241 78.674 -23.051 1.563 1.00205.28 C +ATOM 15108 C ASN H 241 77.547 -23.567 0.688 1.00197.59 C +ATOM 15109 O ASN H 241 76.973 -24.631 0.966 1.00190.08 O +ATOM 15110 CB ASN H 241 79.651 -24.181 1.839 1.00220.32 C +ATOM 15111 CG ASN H 241 81.081 -23.721 1.739 1.00270.87 C +ATOM 15112 OD1 ASN H 241 81.765 -24.027 0.758 1.00380.62 O +ATOM 15113 ND2 ASN H 241 81.563 -23.021 2.767 1.00331.15 N +ATOM 15114 N LYS H 242 77.300 -22.867 -0.420 1.00156.48 N +ATOM 15115 CA LYS H 242 76.266 -23.287 -1.365 1.00128.97 C +ATOM 15116 C LYS H 242 76.627 -24.635 -1.993 1.00145.59 C +ATOM 15117 O LYS H 242 75.751 -25.413 -2.385 1.00101.48 O +ATOM 15118 CB LYS H 242 76.058 -22.219 -2.437 1.00112.08 C +ATOM 15119 CG LYS H 242 75.913 -20.816 -1.878 1.00113.82 C +ATOM 15120 CD LYS H 242 74.639 -20.144 -2.360 1.00130.81 C +ATOM 15121 CE LYS H 242 73.901 -19.478 -1.204 1.00157.99 C +ATOM 15122 NZ LYS H 242 72.733 -18.669 -1.654 1.00149.81 N +ATOM 15123 N ALA H 243 77.936 -24.898 -2.055 1.00206.77 N +ATOM 15124 CA ALA H 243 78.487 -26.181 -2.496 1.00211.81 C +ATOM 15125 C ALA H 243 78.039 -27.329 -1.602 1.00181.90 C +ATOM 15126 O ALA H 243 78.132 -28.495 -2.004 1.00202.94 O +ATOM 15127 CB ALA H 243 80.013 -26.115 -2.525 1.00235.94 C +ATOM 15128 N GLU H 244 77.596 -27.014 -0.384 1.00140.80 N +ATOM 15129 CA GLU H 244 77.209 -28.060 0.553 1.00155.78 C +ATOM 15130 C GLU H 244 75.724 -28.391 0.462 1.00158.57 C +ATOM 15131 O GLU H 244 75.213 -29.075 1.334 1.00123.89 O +ATOM 15132 CB GLU H 244 77.589 -27.677 1.987 1.00163.90 C +ATOM 15133 CG GLU H 244 79.081 -27.764 2.279 1.00162.38 C +ATOM 15134 CD GLU H 244 79.399 -27.641 3.763 1.00158.07 C +ATOM 15135 OE1 GLU H 244 79.364 -26.502 4.292 1.00134.75 O +ATOM 15136 OE2 GLU H 244 79.694 -28.683 4.394 1.00115.78 O +ATOM 15137 N ARG H 245 75.039 -27.872 -0.564 1.00166.73 N +ATOM 15138 CA ARG H 245 73.629 -28.209 -0.825 1.00153.09 C +ATOM 15139 C ARG H 245 73.420 -29.720 -0.919 1.00132.07 C +ATOM 15140 O ARG H 245 72.405 -30.250 -0.475 1.00134.94 O +ATOM 15141 CB ARG H 245 73.080 -27.436 -2.087 1.00149.94 C +ATOM 15142 CG ARG H 245 72.479 -26.156 -1.592 1.00153.03 C +ATOM 15143 CD ARG H 245 71.749 -25.609 -2.848 1.00180.42 C +ATOM 15144 NE ARG H 245 70.800 -26.592 -3.350 1.00199.67 N +ATOM 15145 CZ ARG H 245 69.609 -26.903 -2.847 1.00191.46 C +ATOM 15146 NH1 ARG H 245 69.094 -26.281 -1.800 1.00178.58 N +ATOM 15147 NH2 ARG H 245 68.883 -27.853 -3.442 1.00189.76 N +ATOM 15148 N GLN H 246 74.374 -30.410 -1.538 1.00126.96 N +ATOM 15149 CA GLN H 246 74.210 -31.838 -1.828 1.00130.15 C +ATOM 15150 C GLN H 246 74.827 -32.683 -0.723 1.00113.67 C +ATOM 15151 O GLN H 246 75.171 -33.846 -0.940 1.00109.42 O +ATOM 15152 CB GLN H 246 74.803 -32.206 -3.204 1.00139.42 C +ATOM 15153 CG GLN H 246 74.006 -31.700 -4.407 1.00156.78 C +ATOM 15154 CD GLN H 246 74.196 -30.217 -4.684 1.00167.33 C +ATOM 15155 OE1 GLN H 246 75.306 -29.700 -4.591 1.00143.33 O +ATOM 15156 NE2 GLN H 246 73.094 -29.510 -4.938 1.00170.42 N +ATOM 15157 N ASN H 247 74.999 -32.075 0.449 1.00 93.40 N +ATOM 15158 CA ASN H 247 75.361 -32.800 1.666 1.00111.07 C +ATOM 15159 C ASN H 247 74.598 -34.126 1.768 1.00107.23 C +ATOM 15160 O ASN H 247 73.386 -34.164 1.516 1.00135.56 O +ATOM 15161 CB ASN H 247 75.041 -31.916 2.881 1.00124.94 C +ATOM 15162 CG ASN H 247 75.878 -32.244 4.092 1.00152.00 C +ATOM 15163 OD1 ASN H 247 75.389 -32.820 5.073 1.00142.51 O +ATOM 15164 ND2 ASN H 247 77.155 -31.885 4.030 1.00176.10 N +ATOM 15165 N ASP H 248 75.283 -35.186 2.196 1.00130.85 N +ATOM 15166 CA ASP H 248 74.664 -36.524 2.333 1.00182.31 C +ATOM 15167 C ASP H 248 73.366 -36.492 3.154 1.00223.00 C +ATOM 15168 O ASP H 248 72.339 -37.076 2.768 1.00240.40 O +ATOM 15169 CB ASP H 248 75.630 -37.508 3.015 1.00172.13 C +ATOM 15170 CG ASP H 248 76.799 -37.892 2.136 1.00171.57 C +ATOM 15171 OD1 ASP H 248 76.611 -38.054 0.910 1.00207.28 O +ATOM 15172 OD2 ASP H 248 77.911 -38.044 2.678 1.00141.17 O +ATOM 15173 N ILE H 249 73.433 -35.819 4.299 1.00214.57 N +ATOM 15174 CA ILE H 249 72.313 -35.750 5.225 1.00170.20 C +ATOM 15175 C ILE H 249 71.156 -34.969 4.594 1.00144.49 C +ATOM 15176 O ILE H 249 70.007 -35.438 4.561 1.00184.20 O +ATOM 15177 CB ILE H 249 72.747 -35.084 6.546 1.00158.05 C +ATOM 15178 CG1 ILE H 249 73.821 -35.926 7.238 1.00144.62 C +ATOM 15179 CG2 ILE H 249 71.556 -34.929 7.474 1.00190.09 C +ATOM 15180 CD1 ILE H 249 74.643 -35.163 8.253 1.00147.62 C +ATOM 15181 N LEU H 250 71.468 -33.782 4.078 1.00103.63 N +ATOM 15182 CA LEU H 250 70.455 -32.928 3.458 1.00114.42 C +ATOM 15183 C LEU H 250 69.714 -33.596 2.289 1.00138.48 C +ATOM 15184 O LEU H 250 68.504 -33.403 2.130 1.00168.53 O +ATOM 15185 CB LEU H 250 71.075 -31.615 2.989 1.00104.49 C +ATOM 15186 CG LEU H 250 71.318 -30.581 4.087 1.00114.22 C +ATOM 15187 CD1 LEU H 250 72.194 -29.436 3.606 1.00135.72 C +ATOM 15188 CD2 LEU H 250 69.999 -30.037 4.592 1.00135.99 C +ATOM 15189 N VAL H 251 70.437 -34.361 1.470 1.00156.70 N +ATOM 15190 CA VAL H 251 69.820 -35.063 0.335 1.00141.55 C +ATOM 15191 C VAL H 251 69.064 -36.306 0.798 1.00158.61 C +ATOM 15192 O VAL H 251 68.127 -36.751 0.130 1.00219.98 O +ATOM 15193 CB VAL H 251 70.845 -35.465 -0.741 1.00134.02 C +ATOM 15194 CG1 VAL H 251 71.623 -34.243 -1.210 1.00129.21 C +ATOM 15195 CG2 VAL H 251 71.785 -36.562 -0.233 1.00142.31 C +ATOM 15196 N LYS H 252 69.453 -36.849 1.952 1.00133.31 N +ATOM 15197 CA LYS H 252 68.737 -37.974 2.552 1.00120.78 C +ATOM 15198 C LYS H 252 67.327 -37.554 3.015 1.00142.83 C +ATOM 15199 O LYS H 252 66.330 -38.211 2.689 1.00144.09 O +ATOM 15200 CB LYS H 252 69.560 -38.526 3.716 1.00109.65 C +ATOM 15201 CG LYS H 252 68.926 -39.692 4.453 1.00116.36 C +ATOM 15202 CD LYS H 252 69.826 -40.128 5.603 1.00120.22 C +ATOM 15203 CE LYS H 252 69.043 -40.311 6.900 1.00126.69 C +ATOM 15204 NZ LYS H 252 69.924 -40.485 8.092 1.00110.93 N +ATOM 15205 N TYR H 253 67.248 -36.408 3.695 1.00150.90 N +ATOM 15206 CA TYR H 253 65.970 -35.874 4.196 1.00111.79 C +ATOM 15207 C TYR H 253 65.168 -35.226 3.077 1.00120.30 C +ATOM 15208 O TYR H 253 63.937 -35.271 3.077 1.00150.50 O +ATOM 15209 CB TYR H 253 66.205 -34.877 5.340 1.00 89.43 C +ATOM 15210 CG TYR H 253 66.647 -35.567 6.610 1.00112.49 C +ATOM 15211 CD1 TYR H 253 65.726 -36.181 7.456 1.00130.86 C +ATOM 15212 CD2 TYR H 253 67.992 -35.725 6.906 1.00139.57 C +ATOM 15213 CE1 TYR H 253 66.137 -36.866 8.592 1.00126.57 C +ATOM 15214 CE2 TYR H 253 68.408 -36.430 8.034 1.00145.44 C +ATOM 15215 CZ TYR H 253 67.470 -36.985 8.878 1.00120.90 C +ATOM 15216 OH TYR H 253 67.880 -37.658 10.011 1.00114.77 O +ATOM 15217 N ARG H 254 65.868 -34.622 2.120 1.00119.50 N +ATOM 15218 CA ARG H 254 65.236 -34.173 0.877 1.00119.68 C +ATOM 15219 C ARG H 254 64.521 -35.342 0.192 1.00124.36 C +ATOM 15220 O ARG H 254 63.439 -35.180 -0.367 1.00127.18 O +ATOM 15221 CB ARG H 254 66.278 -33.566 -0.075 1.00124.74 C +ATOM 15222 CG ARG H 254 65.672 -32.951 -1.324 1.00126.07 C +ATOM 15223 CD ARG H 254 66.624 -32.005 -2.023 1.00143.54 C +ATOM 15224 NE ARG H 254 66.930 -30.821 -1.219 1.00135.95 N +ATOM 15225 CZ ARG H 254 68.105 -30.569 -0.643 1.00174.77 C +ATOM 15226 NH1 ARG H 254 69.123 -31.420 -0.754 1.00205.00 N +ATOM 15227 NH2 ARG H 254 68.270 -29.458 0.063 1.00160.10 N +ATOM 15228 N HIS H 255 65.167 -36.507 0.196 1.00138.53 N +ATOM 15229 CA HIS H 255 64.631 -37.700 -0.455 1.00154.83 C +ATOM 15230 C HIS H 255 63.410 -38.234 0.266 1.00143.39 C +ATOM 15231 O HIS H 255 62.503 -38.775 -0.375 1.00198.46 O +ATOM 15232 CB HIS H 255 65.709 -38.800 -0.584 1.00184.68 C +ATOM 15233 CG HIS H 255 66.212 -38.983 -1.984 1.00182.47 C +ATOM 15234 ND1 HIS H 255 67.054 -38.078 -2.595 1.00186.31 N +ATOM 15235 CD2 HIS H 255 65.956 -39.942 -2.905 1.00166.42 C +ATOM 15236 CE1 HIS H 255 67.311 -38.484 -3.826 1.00189.96 C +ATOM 15237 NE2 HIS H 255 66.653 -39.610 -4.040 1.00184.16 N +ATOM 15238 N MET H 256 63.396 -38.120 1.588 1.00105.63 N +ATOM 15239 CA MET H 256 62.251 -38.616 2.343 1.00126.38 C +ATOM 15240 C MET H 256 60.998 -37.778 2.043 1.00140.85 C +ATOM 15241 O MET H 256 59.861 -38.267 2.192 1.00120.85 O +ATOM 15242 CB MET H 256 62.567 -38.656 3.839 1.00142.95 C +ATOM 15243 CG MET H 256 63.830 -39.444 4.178 1.00160.63 C +ATOM 15244 SD MET H 256 63.983 -39.996 5.892 1.00149.00 S +ATOM 15245 CE MET H 256 62.678 -41.241 5.951 1.00 85.78 C +ATOM 15246 N SER H 257 61.210 -36.542 1.577 1.00149.66 N +ATOM 15247 CA SER H 257 60.127 -35.668 1.112 1.00144.15 C +ATOM 15248 C SER H 257 59.704 -36.077 -0.302 1.00149.91 C +ATOM 15249 O SER H 257 58.798 -36.902 -0.454 1.00165.65 O +ATOM 15250 CB SER H 257 60.559 -34.192 1.131 1.00123.18 C +ATOM 15251 OG SER H 257 61.308 -33.892 2.309 1.00110.02 O +TER 15252 SER H 257 +ATOM 15253 N LEU I 2 74.414 -54.680 30.781 1.00144.50 N +ATOM 15254 CA LEU I 2 72.980 -54.525 30.376 1.00124.60 C +ATOM 15255 C LEU I 2 72.215 -53.683 31.414 1.00136.13 C +ATOM 15256 O LEU I 2 71.367 -54.199 32.186 1.00122.18 O +ATOM 15257 CB LEU I 2 72.315 -55.887 30.158 1.00119.56 C +ATOM 15258 CG LEU I 2 72.872 -56.802 29.044 1.00128.32 C +ATOM 15259 CD1 LEU I 2 72.066 -58.098 29.014 1.00133.54 C +ATOM 15260 CD2 LEU I 2 72.915 -56.182 27.641 1.00121.68 C +ATOM 15261 N THR I 3 72.659 -52.423 31.528 1.00152.32 N +ATOM 15262 CA THR I 3 71.902 -51.344 32.180 1.00146.50 C +ATOM 15263 C THR I 3 72.084 -50.045 31.398 1.00178.22 C +ATOM 15264 O THR I 3 71.429 -49.030 31.673 1.00263.63 O +ATOM 15265 CB THR I 3 72.357 -51.059 33.620 1.00127.24 C +ATOM 15266 OG1 THR I 3 73.671 -50.484 33.601 1.00112.17 O +ATOM 15267 CG2 THR I 3 72.314 -52.328 34.466 1.00128.15 C +ATOM 15268 N ALA I 4 72.926 -50.078 30.372 1.00164.28 N +ATOM 15269 CA ALA I 4 72.780 -49.128 29.281 1.00180.75 C +ATOM 15270 C ALA I 4 71.453 -49.372 28.537 1.00185.36 C +ATOM 15271 O ALA I 4 70.789 -50.412 28.705 1.00203.99 O +ATOM 15272 CB ALA I 4 74.030 -49.115 28.389 1.00144.69 C +ATOM 15273 N PRO I 5 70.915 -48.306 27.962 1.00137.40 N +ATOM 15274 CA PRO I 5 69.579 -48.498 27.458 1.00109.28 C +ATOM 15275 C PRO I 5 69.634 -49.275 26.158 1.00126.96 C +ATOM 15276 O PRO I 5 70.726 -49.518 25.637 1.00123.73 O +ATOM 15277 CB PRO I 5 69.098 -47.076 27.217 1.00140.53 C +ATOM 15278 CG PRO I 5 70.331 -46.240 27.037 1.00134.73 C +ATOM 15279 CD PRO I 5 71.477 -46.972 27.667 1.00135.45 C +ATOM 15280 N PRO I 6 68.477 -49.755 25.695 1.00135.65 N +ATOM 15281 CA PRO I 6 68.391 -50.271 24.336 1.00132.54 C +ATOM 15282 C PRO I 6 68.340 -49.148 23.302 1.00116.74 C +ATOM 15283 O PRO I 6 67.828 -48.060 23.559 1.00105.54 O +ATOM 15284 CB PRO I 6 67.098 -51.081 24.329 1.00125.17 C +ATOM 15285 CG PRO I 6 66.329 -50.645 25.525 1.00116.59 C +ATOM 15286 CD PRO I 6 67.243 -49.941 26.473 1.00118.95 C +ATOM 15287 N LYS I 7 68.898 -49.413 22.134 1.00130.84 N +ATOM 15288 CA LYS I 7 68.972 -48.401 21.079 1.00136.07 C +ATOM 15289 C LYS I 7 67.834 -48.544 20.068 1.00141.69 C +ATOM 15290 O LYS I 7 67.104 -49.547 20.074 1.00 99.13 O +ATOM 15291 CB LYS I 7 70.348 -48.442 20.384 1.00132.45 C +ATOM 15292 CG LYS I 7 71.506 -47.959 21.239 1.00110.99 C +ATOM 15293 CD LYS I 7 72.368 -49.088 21.782 1.00 97.14 C +ATOM 15294 CE LYS I 7 73.641 -48.535 22.380 1.00107.28 C +ATOM 15295 NZ LYS I 7 74.154 -49.385 23.493 1.00128.03 N +ATOM 15296 N GLU I 8 67.727 -47.545 19.183 1.00170.38 N +ATOM 15297 CA GLU I 8 66.570 -47.366 18.294 1.00164.00 C +ATOM 15298 C GLU I 8 66.390 -48.487 17.270 1.00157.54 C +ATOM 15299 O GLU I 8 67.247 -48.725 16.442 1.00140.37 O +ATOM 15300 CB GLU I 8 66.610 -45.984 17.569 1.00147.09 C +ATOM 15301 CG GLU I 8 67.464 -45.855 16.325 1.00134.61 C +ATOM 15302 CD GLU I 8 67.274 -44.518 15.614 1.00149.89 C +ATOM 15303 OE1 GLU I 8 66.108 -44.181 15.243 1.00187.53 O +ATOM 15304 OE2 GLU I 8 68.295 -43.828 15.369 1.00137.26 O +ATOM 15305 N ALA I 9 65.271 -49.191 17.384 1.00159.61 N +ATOM 15306 CA ALA I 9 64.857 -50.180 16.405 1.00131.40 C +ATOM 15307 C ALA I 9 63.861 -49.541 15.438 1.00105.18 C +ATOM 15308 O ALA I 9 62.747 -49.185 15.820 1.00 92.52 O +ATOM 15309 CB ALA I 9 64.225 -51.361 17.117 1.00137.75 C +ATOM 15310 N ALA I 10 64.284 -49.398 14.188 1.00 97.70 N +ATOM 15311 CA ALA I 10 63.564 -48.648 13.139 1.00 92.00 C +ATOM 15312 C ALA I 10 63.900 -47.168 13.216 1.00 90.26 C +ATOM 15313 O ALA I 10 64.334 -46.665 14.251 1.00 79.51 O +ATOM 15314 CB ALA I 10 62.052 -48.870 13.175 1.00 82.03 C +ATOM 15315 N ARG I 11 63.766 -46.497 12.073 1.00115.09 N +ATOM 15316 CA ARG I 11 64.244 -45.120 11.896 1.00136.12 C +ATOM 15317 C ARG I 11 63.044 -44.168 11.994 1.00122.28 C +ATOM 15318 O ARG I 11 61.896 -44.541 11.679 1.00150.21 O +ATOM 15319 CB ARG I 11 64.973 -44.951 10.524 1.00152.28 C +ATOM 15320 CG ARG I 11 65.492 -46.291 9.978 1.00160.66 C +ATOM 15321 CD ARG I 11 67.019 -46.134 9.803 1.00152.01 C +ATOM 15322 NE ARG I 11 67.525 -44.797 9.453 1.00146.56 N +ATOM 15323 CZ ARG I 11 68.774 -44.394 9.701 1.00158.84 C +ATOM 15324 NH1 ARG I 11 69.670 -45.224 10.235 1.00176.59 N +ATOM 15325 NH2 ARG I 11 69.163 -43.161 9.378 1.00140.17 N +ATOM 15326 N PRO I 12 63.299 -42.936 12.427 1.00108.88 N +ATOM 15327 CA PRO I 12 62.283 -41.929 12.237 1.00123.43 C +ATOM 15328 C PRO I 12 61.995 -41.698 10.742 1.00119.09 C +ATOM 15329 O PRO I 12 62.844 -41.199 10.012 1.00 81.33 O +ATOM 15330 CB PRO I 12 62.891 -40.668 12.894 1.00124.15 C +ATOM 15331 CG PRO I 12 64.081 -41.138 13.653 1.00119.16 C +ATOM 15332 CD PRO I 12 64.547 -42.366 12.943 1.00123.90 C +ATOM 15333 N THR I 13 60.769 -42.018 10.331 1.00127.19 N +ATOM 15334 CA THR I 13 60.222 -41.552 9.067 1.00122.72 C +ATOM 15335 C THR I 13 59.323 -40.321 9.246 1.00113.47 C +ATOM 15336 O THR I 13 58.858 -40.051 10.352 1.00162.82 O +ATOM 15337 CB THR I 13 59.383 -42.660 8.441 1.00122.13 C +ATOM 15338 OG1 THR I 13 59.078 -42.306 7.087 1.00170.18 O +ATOM 15339 CG2 THR I 13 58.075 -42.932 9.265 1.00 93.14 C +ATOM 15340 N LEU I 14 59.072 -39.563 8.185 1.00100.25 N +ATOM 15341 CA LEU I 14 58.032 -38.526 8.297 1.00107.81 C +ATOM 15342 C LEU I 14 56.672 -39.218 8.228 1.00110.28 C +ATOM 15343 O LEU I 14 56.615 -40.374 7.848 1.00111.19 O +ATOM 15344 CB LEU I 14 58.191 -37.391 7.289 1.00101.17 C +ATOM 15345 CG LEU I 14 58.333 -37.743 5.829 1.00106.93 C +ATOM 15346 CD1 LEU I 14 57.708 -36.663 4.964 1.00114.76 C +ATOM 15347 CD2 LEU I 14 59.801 -37.865 5.497 1.00129.96 C +ATOM 15348 N MET I 15 55.607 -38.583 8.715 1.00108.60 N +ATOM 15349 CA MET I 15 54.434 -39.345 9.184 1.00108.01 C +ATOM 15350 C MET I 15 53.702 -40.003 8.010 1.00101.82 C +ATOM 15351 O MET I 15 53.313 -39.325 7.057 1.00 85.99 O +ATOM 15352 CB MET I 15 53.461 -38.472 9.981 1.00122.68 C +ATOM 15353 CG MET I 15 52.668 -39.267 11.013 1.00122.93 C +ATOM 15354 SD MET I 15 50.944 -38.911 11.332 1.00127.05 S +ATOM 15355 CE MET I 15 50.381 -37.854 9.996 1.00144.69 C +ATOM 15356 N PRO I 16 53.522 -41.341 8.075 1.00100.56 N +ATOM 15357 CA PRO I 16 53.015 -42.172 6.965 1.00 92.10 C +ATOM 15358 C PRO I 16 51.577 -41.880 6.534 1.00101.16 C +ATOM 15359 O PRO I 16 50.641 -42.579 6.922 1.00 87.56 O +ATOM 15360 CB PRO I 16 53.137 -43.598 7.516 1.00 91.90 C +ATOM 15361 CG PRO I 16 53.122 -43.439 8.994 1.00 94.76 C +ATOM 15362 CD PRO I 16 53.860 -42.165 9.251 1.00 95.38 C +ATOM 15363 N ARG I 17 51.418 -40.855 5.705 1.00126.43 N +ATOM 15364 CA ARG I 17 50.120 -40.528 5.112 1.00145.79 C +ATOM 15365 C ARG I 17 49.980 -41.281 3.800 1.00121.82 C +ATOM 15366 O ARG I 17 50.968 -41.503 3.121 1.00 95.88 O +ATOM 15367 CB ARG I 17 50.019 -39.015 4.873 1.00178.05 C +ATOM 15368 CG ARG I 17 49.503 -38.236 6.075 1.00172.76 C +ATOM 15369 CD ARG I 17 49.794 -36.742 5.990 1.00145.13 C +ATOM 15370 NE ARG I 17 51.182 -36.434 6.337 1.00152.87 N +ATOM 15371 CZ ARG I 17 51.737 -35.235 6.196 1.00153.12 C +ATOM 15372 NH1 ARG I 17 51.006 -34.233 5.726 1.00155.21 N +ATOM 15373 NH2 ARG I 17 53.005 -35.032 6.545 1.00132.10 N +ATOM 15374 N ALA I 18 48.764 -41.698 3.460 1.00130.31 N +ATOM 15375 CA ALA I 18 48.554 -42.515 2.259 1.00126.15 C +ATOM 15376 C ALA I 18 47.743 -41.792 1.170 1.00111.82 C +ATOM 15377 O ALA I 18 48.180 -40.763 0.650 1.00 76.49 O +ATOM 15378 CB ALA I 18 47.924 -43.857 2.617 1.00119.34 C +ATOM 15379 N GLN I 19 46.589 -42.351 0.807 1.00100.63 N +ATOM 15380 CA GLN I 19 45.943 -42.003 -0.451 1.00111.74 C +ATOM 15381 C GLN I 19 45.415 -40.565 -0.431 1.00112.75 C +ATOM 15382 O GLN I 19 45.610 -39.791 -1.386 1.00105.11 O +ATOM 15383 CB GLN I 19 44.806 -42.990 -0.754 1.00111.15 C +ATOM 15384 CG GLN I 19 44.164 -42.814 -2.127 1.00122.61 C +ATOM 15385 CD GLN I 19 45.178 -42.854 -3.258 1.00137.93 C +ATOM 15386 OE1 GLN I 19 45.799 -43.890 -3.519 1.00169.47 O +ATOM 15387 NE2 GLN I 19 45.365 -41.723 -3.928 1.00145.11 N +ATOM 15388 N SER I 20 44.669 -40.260 0.627 1.00 92.16 N +ATOM 15389 CA SER I 20 44.124 -38.942 0.849 1.00 78.69 C +ATOM 15390 C SER I 20 45.184 -37.888 0.600 1.00 78.40 C +ATOM 15391 O SER I 20 44.955 -36.912 -0.142 1.00 66.69 O +ATOM 15392 CB SER I 20 43.617 -38.864 2.285 1.00 75.00 C +ATOM 15393 OG SER I 20 42.713 -39.933 2.568 1.00 75.23 O +ATOM 15394 N TYR I 21 46.356 -38.112 1.183 1.00 92.06 N +ATOM 15395 CA TYR I 21 47.504 -37.211 1.001 1.00137.11 C +ATOM 15396 C TYR I 21 47.886 -37.035 -0.478 1.00125.05 C +ATOM 15397 O TYR I 21 48.087 -35.904 -0.958 1.00 64.60 O +ATOM 15398 CB TYR I 21 48.714 -37.732 1.795 1.00149.94 C +ATOM 15399 CG TYR I 21 49.941 -36.845 1.719 1.00159.22 C +ATOM 15400 CD1 TYR I 21 50.028 -35.676 2.465 1.00147.14 C +ATOM 15401 CD2 TYR I 21 51.012 -37.177 0.896 1.00189.49 C +ATOM 15402 CE1 TYR I 21 51.131 -34.852 2.374 1.00160.60 C +ATOM 15403 CE2 TYR I 21 52.128 -36.356 0.809 1.00184.58 C +ATOM 15404 CZ TYR I 21 52.175 -35.192 1.552 1.00164.35 C +ATOM 15405 OH TYR I 21 53.244 -34.338 1.460 1.00178.68 O +ATOM 15406 N LYS I 22 48.013 -38.160 -1.180 1.00122.13 N +ATOM 15407 CA LYS I 22 48.455 -38.153 -2.572 1.00113.70 C +ATOM 15408 C LYS I 22 47.499 -37.367 -3.455 1.00116.23 C +ATOM 15409 O LYS I 22 47.920 -36.636 -4.357 1.00 90.58 O +ATOM 15410 CB LYS I 22 48.591 -39.584 -3.088 1.00 96.66 C +ATOM 15411 CG LYS I 22 49.965 -40.188 -2.853 1.00101.69 C +ATOM 15412 CD LYS I 22 50.936 -39.733 -3.951 1.00119.81 C +ATOM 15413 CE LYS I 22 51.126 -40.850 -4.984 1.00149.48 C +ATOM 15414 NZ LYS I 22 51.792 -42.036 -4.385 1.00163.80 N +ATOM 15415 N ASP I 23 46.205 -37.537 -3.193 1.00123.24 N +ATOM 15416 CA ASP I 23 45.169 -36.767 -3.885 1.00120.33 C +ATOM 15417 C ASP I 23 45.285 -35.288 -3.543 1.00105.69 C +ATOM 15418 O ASP I 23 45.210 -34.429 -4.426 1.00110.47 O +ATOM 15419 CB ASP I 23 43.779 -37.273 -3.490 1.00115.26 C +ATOM 15420 CG ASP I 23 43.496 -38.660 -4.007 1.00111.93 C +ATOM 15421 OD1 ASP I 23 43.858 -38.925 -5.168 1.00106.45 O +ATOM 15422 OD2 ASP I 23 42.905 -39.465 -3.251 1.00 99.57 O +ATOM 15423 N LEU I 24 45.467 -35.012 -2.253 1.00 94.44 N +ATOM 15424 CA LEU I 24 45.467 -33.648 -1.732 1.00104.90 C +ATOM 15425 C LEU I 24 46.636 -32.825 -2.279 1.00102.40 C +ATOM 15426 O LEU I 24 46.500 -31.608 -2.530 1.00 68.70 O +ATOM 15427 CB LEU I 24 45.528 -33.683 -0.200 1.00120.61 C +ATOM 15428 CG LEU I 24 45.531 -32.341 0.559 1.00133.41 C +ATOM 15429 CD1 LEU I 24 44.119 -31.840 0.790 1.00129.86 C +ATOM 15430 CD2 LEU I 24 46.267 -32.488 1.883 1.00136.90 C +ATOM 15431 N THR I 25 47.782 -33.486 -2.450 1.00100.31 N +ATOM 15432 CA THR I 25 48.983 -32.809 -2.930 1.00102.36 C +ATOM 15433 C THR I 25 48.912 -32.494 -4.435 1.00121.15 C +ATOM 15434 O THR I 25 49.226 -31.369 -4.864 1.00 83.12 O +ATOM 15435 CB THR I 25 50.239 -33.644 -2.633 1.00 88.30 C +ATOM 15436 OG1 THR I 25 50.020 -35.005 -3.021 1.00 70.71 O +ATOM 15437 CG2 THR I 25 50.583 -33.575 -1.160 1.00 71.45 C +ATOM 15438 N HIS I 26 48.505 -33.490 -5.226 1.00144.28 N +ATOM 15439 CA HIS I 26 48.463 -33.372 -6.691 1.00145.30 C +ATOM 15440 C HIS I 26 47.161 -32.704 -7.167 1.00117.74 C +ATOM 15441 O HIS I 26 46.588 -33.076 -8.184 1.00107.84 O +ATOM 15442 CB HIS I 26 48.652 -34.759 -7.341 1.00139.24 C +ATOM 15443 CG HIS I 26 49.998 -35.368 -7.088 1.00134.97 C +ATOM 15444 ND1 HIS I 26 50.379 -35.834 -5.848 1.00147.14 N +ATOM 15445 CD2 HIS I 26 51.064 -35.557 -7.903 1.00135.84 C +ATOM 15446 CE1 HIS I 26 51.622 -36.279 -5.909 1.00150.81 C +ATOM 15447 NE2 HIS I 26 52.060 -36.126 -7.145 1.00147.34 N +ATOM 15448 N LEU I 27 46.675 -31.737 -6.403 1.00105.34 N +ATOM 15449 CA LEU I 27 45.496 -30.995 -6.803 1.00106.45 C +ATOM 15450 C LEU I 27 45.945 -29.830 -7.668 1.00 86.99 C +ATOM 15451 O LEU I 27 46.855 -29.097 -7.283 1.00 87.17 O +ATOM 15452 CB LEU I 27 44.703 -30.504 -5.565 1.00105.90 C +ATOM 15453 CG LEU I 27 43.655 -31.487 -5.028 1.00110.73 C +ATOM 15454 CD1 LEU I 27 43.167 -31.071 -3.657 1.00104.81 C +ATOM 15455 CD2 LEU I 27 42.473 -31.624 -5.986 1.00120.00 C +ATOM 15456 N PRO I 28 45.241 -29.591 -8.787 1.00 82.36 N +ATOM 15457 CA PRO I 28 45.507 -28.417 -9.633 1.00 88.44 C +ATOM 15458 C PRO I 28 45.409 -27.086 -8.906 1.00 93.25 C +ATOM 15459 O PRO I 28 44.427 -26.822 -8.245 1.00 99.41 O +ATOM 15460 CB PRO I 28 44.419 -28.490 -10.704 1.00 94.04 C +ATOM 15461 CG PRO I 28 43.303 -29.249 -10.058 1.00 99.51 C +ATOM 15462 CD PRO I 28 43.966 -30.243 -9.144 1.00 92.44 C +ATOM 15463 N ALA I 29 46.441 -26.261 -9.015 1.00132.93 N +ATOM 15464 CA ALA I 29 46.577 -25.083 -8.151 1.00144.61 C +ATOM 15465 C ALA I 29 45.576 -23.966 -8.532 1.00131.35 C +ATOM 15466 O ALA I 29 45.205 -23.818 -9.701 1.00101.58 O +ATOM 15467 CB ALA I 29 48.027 -24.571 -8.169 1.00153.52 C +ATOM 15468 N PRO I 30 45.136 -23.182 -7.536 1.00123.14 N +ATOM 15469 CA PRO I 30 44.260 -22.028 -7.758 1.00120.05 C +ATOM 15470 C PRO I 30 45.024 -20.820 -8.314 1.00 95.53 C +ATOM 15471 O PRO I 30 46.248 -20.857 -8.387 1.00 75.42 O +ATOM 15472 CB PRO I 30 43.756 -21.713 -6.351 1.00135.30 C +ATOM 15473 CG PRO I 30 44.863 -22.150 -5.448 1.00133.34 C +ATOM 15474 CD PRO I 30 45.523 -23.323 -6.118 1.00124.41 C +ATOM 15475 N THR I 31 44.306 -19.738 -8.617 1.00106.92 N +ATOM 15476 CA THR I 31 44.923 -18.511 -9.157 1.00121.23 C +ATOM 15477 C THR I 31 45.815 -17.793 -8.137 1.00123.53 C +ATOM 15478 O THR I 31 46.758 -17.108 -8.508 1.00124.59 O +ATOM 15479 CB THR I 31 43.877 -17.499 -9.708 1.00129.08 C +ATOM 15480 OG1 THR I 31 42.881 -17.208 -8.718 1.00134.78 O +ATOM 15481 CG2 THR I 31 43.197 -18.043 -10.959 1.00133.61 C +ATOM 15482 N GLY I 32 45.505 -17.956 -6.858 1.00130.95 N +ATOM 15483 CA GLY I 32 46.407 -17.562 -5.777 1.00127.94 C +ATOM 15484 C GLY I 32 46.061 -18.364 -4.536 1.00135.08 C +ATOM 15485 O GLY I 32 44.938 -18.864 -4.424 1.00151.77 O +ATOM 15486 N LYS I 33 47.016 -18.537 -3.620 1.00123.83 N +ATOM 15487 CA LYS I 33 46.722 -19.257 -2.380 1.00113.61 C +ATOM 15488 C LYS I 33 45.781 -18.429 -1.493 1.00131.85 C +ATOM 15489 O LYS I 33 45.767 -17.201 -1.596 1.00118.53 O +ATOM 15490 CB LYS I 33 47.993 -19.604 -1.612 1.00 86.20 C +ATOM 15491 CG LYS I 33 48.571 -20.947 -1.965 1.00 91.01 C +ATOM 15492 CD LYS I 33 49.909 -21.151 -1.293 1.00109.28 C +ATOM 15493 CE LYS I 33 50.776 -22.130 -2.078 1.00139.92 C +ATOM 15494 NZ LYS I 33 52.158 -22.212 -1.529 1.00135.11 N +ATOM 15495 N ILE I 34 44.951 -19.106 -0.693 1.00135.71 N +ATOM 15496 CA ILE I 34 43.937 -18.436 0.110 1.00117.22 C +ATOM 15497 C ILE I 34 44.384 -18.484 1.571 1.00 99.60 C +ATOM 15498 O ILE I 34 45.079 -19.407 1.986 1.00 60.00 O +ATOM 15499 CB ILE I 34 42.527 -19.047 -0.112 1.00131.67 C +ATOM 15500 CG1 ILE I 34 42.042 -18.779 -1.544 1.00133.57 C +ATOM 15501 CG2 ILE I 34 41.493 -18.450 0.830 1.00159.26 C +ATOM 15502 CD1 ILE I 34 41.813 -20.045 -2.341 1.00159.61 C +ATOM 15503 N PHE I 35 44.160 -17.367 2.266 1.00115.08 N +ATOM 15504 CA PHE I 35 44.566 -17.184 3.659 1.00101.41 C +ATOM 15505 C PHE I 35 43.528 -17.802 4.564 1.00102.76 C +ATOM 15506 O PHE I 35 42.357 -17.427 4.504 1.00103.30 O +ATOM 15507 CB PHE I 35 44.636 -15.698 3.988 1.00 96.06 C +ATOM 15508 CG PHE I 35 45.952 -15.055 3.684 1.00 73.52 C +ATOM 15509 CD1 PHE I 35 47.135 -15.631 4.080 1.00 53.79 C +ATOM 15510 CD2 PHE I 35 45.973 -13.782 3.112 1.00 72.28 C +ATOM 15511 CE1 PHE I 35 48.318 -15.022 3.759 1.00 61.62 C +ATOM 15512 CE2 PHE I 35 47.161 -13.133 2.866 1.00 61.42 C +ATOM 15513 CZ PHE I 35 48.336 -13.757 3.178 1.00 62.20 C +ATOM 15514 N VAL I 36 43.961 -18.694 5.443 1.00 92.48 N +ATOM 15515 CA VAL I 36 43.006 -19.406 6.266 1.00 89.64 C +ATOM 15516 C VAL I 36 43.403 -19.409 7.747 1.00 87.18 C +ATOM 15517 O VAL I 36 44.588 -19.391 8.084 1.00100.34 O +ATOM 15518 CB VAL I 36 42.833 -20.842 5.764 1.00 78.28 C +ATOM 15519 CG1 VAL I 36 44.036 -21.693 6.154 1.00103.69 C +ATOM 15520 CG2 VAL I 36 41.568 -21.436 6.326 1.00 71.78 C +ATOM 15521 N SER I 37 42.403 -19.452 8.625 1.00 65.60 N +ATOM 15522 CA SER I 37 42.645 -19.517 10.042 1.00 52.46 C +ATOM 15523 C SER I 37 42.043 -20.765 10.591 1.00 46.85 C +ATOM 15524 O SER I 37 40.872 -21.052 10.348 1.00 52.30 O +ATOM 15525 CB SER I 37 41.985 -18.334 10.701 1.00 54.29 C +ATOM 15526 OG SER I 37 42.722 -17.145 10.473 1.00 80.71 O +ATOM 15527 N VAL I 38 42.792 -21.503 11.391 1.00 39.05 N +ATOM 15528 CA VAL I 38 42.144 -22.526 12.193 1.00 51.99 C +ATOM 15529 C VAL I 38 42.377 -22.222 13.673 1.00 68.31 C +ATOM 15530 O VAL I 38 43.543 -22.268 14.136 1.00112.21 O +ATOM 15531 CB VAL I 38 42.668 -23.943 11.870 1.00 51.49 C +ATOM 15532 CG1 VAL I 38 42.024 -24.982 12.789 1.00 55.00 C +ATOM 15533 CG2 VAL I 38 42.451 -24.316 10.404 1.00 37.15 C +ATOM 15534 N TYR I 39 41.278 -22.025 14.433 1.00 56.15 N +ATOM 15535 CA TYR I 39 41.360 -21.781 15.878 1.00 51.19 C +ATOM 15536 C TYR I 39 41.337 -23.086 16.719 1.00 63.30 C +ATOM 15537 O TYR I 39 42.261 -23.360 17.509 1.00 60.40 O +ATOM 15538 CB TYR I 39 40.262 -20.852 16.292 1.00 45.77 C +ATOM 15539 CG TYR I 39 40.637 -19.418 16.070 1.00 48.65 C +ATOM 15540 CD1 TYR I 39 40.584 -18.853 14.825 1.00 47.42 C +ATOM 15541 CD2 TYR I 39 40.985 -18.591 17.149 1.00 63.68 C +ATOM 15542 CE1 TYR I 39 40.900 -17.511 14.641 1.00 55.45 C +ATOM 15543 CE2 TYR I 39 41.282 -17.236 16.976 1.00 59.08 C +ATOM 15544 CZ TYR I 39 41.250 -16.706 15.714 1.00 53.49 C +ATOM 15545 OH TYR I 39 41.531 -15.375 15.546 1.00 50.51 O +ATOM 15546 N ASN I 40 40.370 -23.954 16.455 1.00 69.94 N +ATOM 15547 CA ASN I 40 40.292 -25.210 17.186 1.00 72.46 C +ATOM 15548 C ASN I 40 39.305 -26.210 16.582 1.00 77.14 C +ATOM 15549 O ASN I 40 38.159 -25.868 16.284 1.00 73.30 O +ATOM 15550 CB ASN I 40 39.892 -24.934 18.630 1.00 76.25 C +ATOM 15551 CG ASN I 40 40.202 -26.099 19.543 1.00104.84 C +ATOM 15552 OD1 ASN I 40 39.300 -26.699 20.123 1.00107.01 O +ATOM 15553 ND2 ASN I 40 41.488 -26.431 19.671 1.00116.62 N +ATOM 15554 N ILE I 41 39.743 -27.462 16.456 1.00 68.41 N +ATOM 15555 CA ILE I 41 38.849 -28.554 16.162 1.00 65.57 C +ATOM 15556 C ILE I 41 38.810 -29.523 17.349 1.00 77.43 C +ATOM 15557 O ILE I 41 39.820 -30.158 17.661 1.00110.00 O +ATOM 15558 CB ILE I 41 39.278 -29.292 14.876 1.00 61.73 C +ATOM 15559 CG1 ILE I 41 38.819 -28.534 13.627 1.00 66.65 C +ATOM 15560 CG2 ILE I 41 38.597 -30.668 14.808 1.00 87.78 C +ATOM 15561 CD1 ILE I 41 39.536 -27.248 13.340 1.00 54.98 C +ATOM 15562 N GLN I 42 37.635 -29.698 17.966 1.00 75.70 N +ATOM 15563 CA GLN I 42 37.540 -30.423 19.245 1.00 84.06 C +ATOM 15564 C GLN I 42 37.281 -31.909 19.072 1.00 74.28 C +ATOM 15565 O GLN I 42 36.753 -32.337 18.055 1.00 60.62 O +ATOM 15566 CB GLN I 42 36.428 -29.856 20.124 1.00105.17 C +ATOM 15567 CG GLN I 42 36.650 -28.426 20.582 1.00123.54 C +ATOM 15568 CD GLN I 42 35.561 -27.478 20.081 1.00142.90 C +ATOM 15569 OE1 GLN I 42 34.520 -27.319 20.727 1.00136.01 O +ATOM 15570 NE2 GLN I 42 35.777 -26.881 18.906 1.00120.16 N +ATOM 15571 N ASP I 43 37.658 -32.679 20.091 1.00 67.84 N +ATOM 15572 CA ASP I 43 37.297 -34.085 20.190 1.00 64.07 C +ATOM 15573 C ASP I 43 35.889 -34.217 20.732 1.00 56.56 C +ATOM 15574 O ASP I 43 35.685 -34.700 21.840 1.00 45.45 O +ATOM 15575 CB ASP I 43 38.273 -34.811 21.127 1.00 93.48 C +ATOM 15576 CG ASP I 43 38.083 -36.339 21.114 1.00108.56 C +ATOM 15577 OD1 ASP I 43 38.042 -36.919 20.012 1.00160.30 O +ATOM 15578 OD2 ASP I 43 38.007 -36.976 22.192 1.00 99.12 O +ATOM 15579 N GLU I 44 34.910 -33.754 19.953 1.00 82.63 N +ATOM 15580 CA GLU I 44 33.474 -33.743 20.365 1.00 78.54 C +ATOM 15581 C GLU I 44 32.897 -35.170 20.469 1.00 59.55 C +ATOM 15582 O GLU I 44 31.683 -35.346 20.549 1.00 37.83 O +ATOM 15583 CB GLU I 44 32.616 -32.858 19.406 1.00 66.05 C +ATOM 15584 CG GLU I 44 32.562 -31.369 19.770 1.00 75.02 C +ATOM 15585 CD GLU I 44 31.757 -30.509 18.770 1.00 83.29 C +ATOM 15586 OE1 GLU I 44 30.640 -30.888 18.346 1.00 66.92 O +ATOM 15587 OE2 GLU I 44 32.199 -29.383 18.459 1.00 98.94 O +ATOM 15588 N THR I 45 33.791 -36.170 20.491 1.00 56.71 N +ATOM 15589 CA THR I 45 33.400 -37.564 20.337 1.00 77.03 C +ATOM 15590 C THR I 45 32.786 -38.120 21.619 1.00 67.83 C +ATOM 15591 O THR I 45 31.837 -38.893 21.555 1.00 86.31 O +ATOM 15592 CB THR I 45 34.556 -38.471 19.804 1.00 95.34 C +ATOM 15593 OG1 THR I 45 34.044 -39.739 19.409 1.00 97.30 O +ATOM 15594 CG2 THR I 45 35.630 -38.717 20.861 1.00 99.49 C +ATOM 15595 N GLY I 46 33.378 -37.805 22.760 1.00 65.27 N +ATOM 15596 CA GLY I 46 32.839 -38.222 24.075 1.00 89.90 C +ATOM 15597 C GLY I 46 33.337 -39.570 24.612 1.00 90.60 C +ATOM 15598 O GLY I 46 32.700 -40.251 25.416 1.00 83.35 O +ATOM 15599 N GLN I 47 34.441 -40.030 24.083 1.00 90.64 N +ATOM 15600 CA GLN I 47 34.678 -41.424 24.144 1.00 79.19 C +ATOM 15601 C GLN I 47 36.082 -41.707 24.616 1.00 77.12 C +ATOM 15602 O GLN I 47 37.037 -41.033 24.225 1.00 63.46 O +ATOM 15603 CB GLN I 47 34.401 -42.035 22.783 1.00 83.29 C +ATOM 15604 CG GLN I 47 32.929 -42.051 22.391 1.00 66.95 C +ATOM 15605 CD GLN I 47 32.031 -42.617 23.479 1.00 80.11 C +ATOM 15606 OE1 GLN I 47 32.060 -43.806 23.764 1.00 81.94 O +ATOM 15607 NE2 GLN I 47 31.254 -41.768 24.115 1.00 92.67 N +ATOM 15608 N PHE I 48 36.176 -42.713 25.480 1.00 93.24 N +ATOM 15609 CA PHE I 48 37.446 -43.154 26.060 1.00102.83 C +ATOM 15610 C PHE I 48 37.662 -44.644 25.822 1.00141.08 C +ATOM 15611 O PHE I 48 36.723 -45.379 25.449 1.00220.18 O +ATOM 15612 CB PHE I 48 37.480 -42.897 27.578 1.00 82.12 C +ATOM 15613 CG PHE I 48 37.463 -41.465 27.930 1.00 67.42 C +ATOM 15614 CD1 PHE I 48 36.300 -40.740 27.790 1.00 95.18 C +ATOM 15615 CD2 PHE I 48 38.612 -40.817 28.243 1.00 60.61 C +ATOM 15616 CE1 PHE I 48 36.280 -39.387 27.991 1.00105.79 C +ATOM 15617 CE2 PHE I 48 38.611 -39.471 28.450 1.00 71.05 C +ATOM 15618 CZ PHE I 48 37.442 -38.755 28.343 1.00 93.10 C +ATOM 15619 N LYS I 49 38.894 -45.090 26.084 1.00113.78 N +ATOM 15620 CA LYS I 49 39.292 -46.468 25.825 1.00 79.79 C +ATOM 15621 C LYS I 49 38.830 -47.342 26.954 1.00 74.35 C +ATOM 15622 O LYS I 49 38.713 -46.879 28.097 1.00 65.92 O +ATOM 15623 CB LYS I 49 40.794 -46.581 25.642 1.00 78.98 C +ATOM 15624 CG LYS I 49 41.290 -45.861 24.390 1.00 92.13 C +ATOM 15625 CD LYS I 49 42.740 -46.097 23.994 1.00 98.70 C +ATOM 15626 CE LYS I 49 42.943 -45.450 22.622 1.00 94.60 C +ATOM 15627 NZ LYS I 49 44.295 -45.618 22.023 1.00111.42 N +ATOM 15628 N PRO I 50 38.449 -48.585 26.618 1.00 89.70 N +ATOM 15629 CA PRO I 50 37.916 -49.535 27.608 1.00109.25 C +ATOM 15630 C PRO I 50 39.044 -50.210 28.360 1.00134.83 C +ATOM 15631 O PRO I 50 40.233 -50.064 27.993 1.00166.51 O +ATOM 15632 CB PRO I 50 37.162 -50.567 26.761 1.00107.80 C +ATOM 15633 CG PRO I 50 37.848 -50.515 25.430 1.00130.60 C +ATOM 15634 CD PRO I 50 38.316 -49.095 25.241 1.00104.48 C +ATOM 15635 N TYR I 51 38.689 -50.930 29.419 1.00129.70 N +ATOM 15636 CA TYR I 51 39.669 -51.736 30.133 1.00124.06 C +ATOM 15637 C TYR I 51 40.421 -52.606 29.128 1.00144.32 C +ATOM 15638 O TYR I 51 39.795 -53.177 28.228 1.00132.97 O +ATOM 15639 CB TYR I 51 38.992 -52.624 31.174 1.00 99.07 C +ATOM 15640 CG TYR I 51 39.990 -53.221 32.122 1.00125.48 C +ATOM 15641 CD1 TYR I 51 40.417 -52.504 33.228 1.00153.55 C +ATOM 15642 CD2 TYR I 51 40.553 -54.480 31.899 1.00149.95 C +ATOM 15643 CE1 TYR I 51 41.352 -53.023 34.109 1.00182.02 C +ATOM 15644 CE2 TYR I 51 41.485 -55.023 32.795 1.00179.44 C +ATOM 15645 CZ TYR I 51 41.905 -54.264 33.878 1.00190.54 C +ATOM 15646 OH TYR I 51 42.822 -54.731 34.799 1.00208.43 O +ATOM 15647 N PRO I 52 41.770 -52.699 29.256 1.00136.79 N +ATOM 15648 CA PRO I 52 42.644 -52.223 30.337 1.00108.69 C +ATOM 15649 C PRO I 52 43.286 -50.866 30.155 1.00123.97 C +ATOM 15650 O PRO I 52 44.249 -50.568 30.873 1.00155.14 O +ATOM 15651 CB PRO I 52 43.746 -53.266 30.351 1.00106.12 C +ATOM 15652 CG PRO I 52 43.897 -53.634 28.907 1.00118.98 C +ATOM 15653 CD PRO I 52 42.509 -53.566 28.317 1.00134.79 C +ATOM 15654 N ALA I 53 42.764 -50.031 29.253 1.00120.52 N +ATOM 15655 CA ALA I 53 43.307 -48.678 29.114 1.00116.48 C +ATOM 15656 C ALA I 53 43.108 -47.862 30.397 1.00107.22 C +ATOM 15657 O ALA I 53 42.256 -48.201 31.251 1.00 72.39 O +ATOM 15658 CB ALA I 53 42.679 -47.956 27.944 1.00123.43 C +ATOM 15659 N SER I 54 43.897 -46.793 30.538 1.00111.15 N +ATOM 15660 CA SER I 54 43.622 -45.827 31.588 1.00 97.86 C +ATOM 15661 C SER I 54 42.232 -45.258 31.369 1.00117.57 C +ATOM 15662 O SER I 54 41.759 -45.074 30.235 1.00141.22 O +ATOM 15663 CB SER I 54 44.628 -44.694 31.617 1.00 71.19 C +ATOM 15664 OG SER I 54 44.088 -43.547 32.268 1.00 62.49 O +ATOM 15665 N ASN I 55 41.531 -45.064 32.476 1.00107.07 N +ATOM 15666 CA ASN I 55 40.194 -44.497 32.443 1.00100.60 C +ATOM 15667 C ASN I 55 40.156 -43.221 31.603 1.00 97.35 C +ATOM 15668 O ASN I 55 39.131 -42.857 31.000 1.00101.41 O +ATOM 15669 CB ASN I 55 39.777 -44.189 33.868 1.00 95.74 C +ATOM 15670 CG ASN I 55 38.307 -43.939 33.993 1.00128.72 C +ATOM 15671 OD1 ASN I 55 37.499 -44.316 33.145 1.00139.03 O +ATOM 15672 ND2 ASN I 55 37.949 -43.325 35.082 1.00150.08 N +ATOM 15673 N PHE I 56 41.301 -42.537 31.575 1.00 97.51 N +ATOM 15674 CA PHE I 56 41.405 -41.188 31.016 1.00 88.16 C +ATOM 15675 C PHE I 56 41.925 -41.200 29.590 1.00101.18 C +ATOM 15676 O PHE I 56 42.155 -40.138 29.003 1.00 88.51 O +ATOM 15677 CB PHE I 56 42.376 -40.338 31.837 1.00 98.12 C +ATOM 15678 CG PHE I 56 41.989 -40.189 33.268 1.00109.90 C +ATOM 15679 CD1 PHE I 56 40.771 -39.629 33.635 1.00107.60 C +ATOM 15680 CD2 PHE I 56 42.815 -40.667 34.247 1.00131.75 C +ATOM 15681 CE1 PHE I 56 40.380 -39.573 34.962 1.00 87.32 C +ATOM 15682 CE2 PHE I 56 42.445 -40.568 35.579 1.00136.50 C +ATOM 15683 CZ PHE I 56 41.223 -40.015 35.936 1.00 87.62 C +ATOM 15684 N SER I 57 42.250 -42.373 29.059 1.00108.61 N +ATOM 15685 CA SER I 57 42.750 -42.433 27.689 1.00115.96 C +ATOM 15686 C SER I 57 41.599 -42.192 26.716 1.00108.82 C +ATOM 15687 O SER I 57 40.643 -42.978 26.631 1.00148.39 O +ATOM 15688 CB SER I 57 43.446 -43.774 27.418 1.00154.26 C +ATOM 15689 OG SER I 57 44.713 -43.802 28.060 1.00165.35 O +ATOM 15690 N THR I 58 41.667 -41.083 26.005 1.00 78.56 N +ATOM 15691 CA THR I 58 40.648 -40.788 25.025 1.00 91.45 C +ATOM 15692 C THR I 58 40.682 -41.757 23.867 1.00 83.39 C +ATOM 15693 O THR I 58 41.729 -42.236 23.456 1.00100.53 O +ATOM 15694 CB THR I 58 40.845 -39.384 24.464 1.00102.70 C +ATOM 15695 OG1 THR I 58 42.110 -39.296 23.812 1.00 85.74 O +ATOM 15696 CG2 THR I 58 40.824 -38.400 25.587 1.00116.08 C +ATOM 15697 N ALA I 59 39.552 -41.951 23.242 1.00 80.60 N +ATOM 15698 CA ALA I 59 39.556 -42.853 22.124 1.00102.20 C +ATOM 15699 C ALA I 59 40.208 -42.244 20.883 1.00 81.96 C +ATOM 15700 O ALA I 59 40.599 -42.972 19.975 1.00 75.99 O +ATOM 15701 CB ALA I 59 38.148 -43.316 21.820 1.00121.91 C +ATOM 15702 N VAL I 60 40.319 -40.926 20.853 1.00 69.29 N +ATOM 15703 CA VAL I 60 40.738 -40.234 19.666 1.00 82.13 C +ATOM 15704 C VAL I 60 41.738 -39.189 20.068 1.00 68.96 C +ATOM 15705 O VAL I 60 41.577 -38.541 21.099 1.00 77.54 O +ATOM 15706 CB VAL I 60 39.541 -39.528 19.001 1.00128.22 C +ATOM 15707 CG1 VAL I 60 39.956 -38.743 17.755 1.00127.97 C +ATOM 15708 CG2 VAL I 60 38.447 -40.532 18.640 1.00161.49 C +ATOM 15709 N PRO I 61 42.737 -38.954 19.222 1.00 60.14 N +ATOM 15710 CA PRO I 61 43.775 -38.021 19.637 1.00 71.15 C +ATOM 15711 C PRO I 61 43.258 -36.603 19.588 1.00 75.35 C +ATOM 15712 O PRO I 61 42.404 -36.285 18.747 1.00 43.34 O +ATOM 15713 CB PRO I 61 44.870 -38.206 18.595 1.00 74.54 C +ATOM 15714 CG PRO I 61 44.184 -38.865 17.440 1.00 71.47 C +ATOM 15715 CD PRO I 61 43.157 -39.745 18.068 1.00 73.50 C +ATOM 15716 N GLN I 62 43.777 -35.766 20.494 1.00 69.58 N +ATOM 15717 CA GLN I 62 43.252 -34.421 20.682 1.00 65.63 C +ATOM 15718 C GLN I 62 44.012 -33.481 19.802 1.00 53.41 C +ATOM 15719 O GLN I 62 44.210 -32.334 20.162 1.00 87.65 O +ATOM 15720 CB GLN I 62 43.411 -33.968 22.148 1.00 87.91 C +ATOM 15721 CG GLN I 62 42.871 -34.940 23.193 1.00 86.05 C +ATOM 15722 CD GLN I 62 41.399 -35.218 23.004 1.00 80.08 C +ATOM 15723 OE1 GLN I 62 40.549 -34.402 23.347 1.00 78.30 O +ATOM 15724 NE2 GLN I 62 41.091 -36.347 22.396 1.00 89.67 N +ATOM 15725 N SER I 63 44.365 -33.933 18.625 1.00 53.50 N +ATOM 15726 CA SER I 63 45.352 -33.256 17.827 1.00 69.42 C +ATOM 15727 C SER I 63 44.800 -32.844 16.455 1.00 93.26 C +ATOM 15728 O SER I 63 45.552 -32.403 15.569 1.00104.54 O +ATOM 15729 CB SER I 63 46.563 -34.178 17.666 1.00 95.80 C +ATOM 15730 OG SER I 63 46.270 -35.391 16.981 1.00109.30 O +ATOM 15731 N ALA I 64 43.481 -32.940 16.299 1.00 81.54 N +ATOM 15732 CA ALA I 64 42.849 -32.722 15.011 1.00 91.37 C +ATOM 15733 C ALA I 64 43.169 -31.346 14.389 1.00 74.99 C +ATOM 15734 O ALA I 64 43.362 -31.212 13.163 1.00 77.26 O +ATOM 15735 CB ALA I 64 41.350 -32.902 15.159 1.00109.98 C +ATOM 15736 N THR I 65 43.165 -30.330 15.230 1.00 60.74 N +ATOM 15737 CA THR I 65 43.446 -28.981 14.801 1.00 67.10 C +ATOM 15738 C THR I 65 44.706 -28.917 13.952 1.00 64.52 C +ATOM 15739 O THR I 65 44.745 -28.265 12.917 1.00 45.58 O +ATOM 15740 CB THR I 65 43.641 -28.091 16.035 1.00 91.53 C +ATOM 15741 OG1 THR I 65 42.710 -28.489 17.051 1.00116.96 O +ATOM 15742 CG2 THR I 65 43.460 -26.605 15.690 1.00 78.41 C +ATOM 15743 N ALA I 66 45.782 -29.492 14.471 1.00100.82 N +ATOM 15744 CA ALA I 66 47.070 -29.339 13.838 1.00123.74 C +ATOM 15745 C ALA I 66 47.055 -30.130 12.529 1.00 99.78 C +ATOM 15746 O ALA I 66 47.734 -29.743 11.555 1.00114.41 O +ATOM 15747 CB ALA I 66 48.185 -29.789 14.789 1.00126.33 C +ATOM 15748 N MET I 67 46.338 -31.258 12.537 1.00 66.43 N +ATOM 15749 CA MET I 67 46.266 -32.112 11.350 1.00 91.21 C +ATOM 15750 C MET I 67 45.556 -31.357 10.227 1.00 93.83 C +ATOM 15751 O MET I 67 45.973 -31.386 9.061 1.00 77.89 O +ATOM 15752 CB MET I 67 45.514 -33.408 11.647 1.00 98.41 C +ATOM 15753 CG MET I 67 46.242 -34.419 12.516 1.00 98.36 C +ATOM 15754 SD MET I 67 45.123 -35.724 13.067 1.00128.10 S +ATOM 15755 CE MET I 67 46.261 -36.841 13.886 1.00143.35 C +ATOM 15756 N LEU I 68 44.510 -30.631 10.598 1.00 89.15 N +ATOM 15757 CA LEU I 68 43.776 -29.847 9.622 1.00 81.57 C +ATOM 15758 C LEU I 68 44.652 -28.750 9.058 1.00 96.73 C +ATOM 15759 O LEU I 68 44.625 -28.506 7.860 1.00109.61 O +ATOM 15760 CB LEU I 68 42.527 -29.211 10.232 1.00 95.57 C +ATOM 15761 CG LEU I 68 41.838 -28.186 9.314 1.00 89.37 C +ATOM 15762 CD1 LEU I 68 41.271 -28.876 8.084 1.00 94.87 C +ATOM 15763 CD2 LEU I 68 40.739 -27.420 10.028 1.00 95.30 C +ATOM 15764 N VAL I 69 45.385 -28.044 9.925 1.00103.29 N +ATOM 15765 CA VAL I 69 46.233 -26.943 9.467 1.00 85.24 C +ATOM 15766 C VAL I 69 47.241 -27.502 8.478 1.00 90.57 C +ATOM 15767 O VAL I 69 47.519 -26.906 7.432 1.00 91.41 O +ATOM 15768 CB VAL I 69 46.974 -26.245 10.625 1.00 65.56 C +ATOM 15769 CG1 VAL I 69 47.965 -25.238 10.066 1.00 60.74 C +ATOM 15770 CG2 VAL I 69 46.009 -25.507 11.539 1.00102.09 C +ATOM 15771 N THR I 70 47.810 -28.648 8.830 1.00 88.58 N +ATOM 15772 CA THR I 70 48.826 -29.273 7.999 1.00 83.86 C +ATOM 15773 C THR I 70 48.226 -29.661 6.661 1.00 98.58 C +ATOM 15774 O THR I 70 48.852 -29.462 5.603 1.00112.51 O +ATOM 15775 CB THR I 70 49.416 -30.497 8.713 1.00 78.08 C +ATOM 15776 OG1 THR I 70 49.937 -30.078 9.981 1.00 90.51 O +ATOM 15777 CG2 THR I 70 50.537 -31.128 7.886 1.00 88.96 C +ATOM 15778 N ALA I 71 47.040 -30.273 6.698 1.00 92.45 N +ATOM 15779 CA ALA I 71 46.377 -30.684 5.452 1.00 97.63 C +ATOM 15780 C ALA I 71 46.089 -29.453 4.572 1.00 94.69 C +ATOM 15781 O ALA I 71 46.257 -29.483 3.350 1.00 57.60 O +ATOM 15782 CB ALA I 71 45.103 -31.448 5.759 1.00 90.80 C +ATOM 15783 N LEU I 72 45.661 -28.366 5.211 1.00110.22 N +ATOM 15784 CA LEU I 72 45.363 -27.123 4.489 1.00128.01 C +ATOM 15785 C LEU I 72 46.615 -26.579 3.829 1.00148.82 C +ATOM 15786 O LEU I 72 46.529 -25.869 2.833 1.00144.14 O +ATOM 15787 CB LEU I 72 44.783 -26.064 5.431 1.00123.60 C +ATOM 15788 CG LEU I 72 43.385 -26.353 5.970 1.00115.82 C +ATOM 15789 CD1 LEU I 72 43.110 -25.480 7.183 1.00 89.45 C +ATOM 15790 CD2 LEU I 72 42.325 -26.136 4.907 1.00133.53 C +ATOM 15791 N LYS I 73 47.779 -26.896 4.399 1.00141.41 N +ATOM 15792 CA LYS I 73 49.043 -26.424 3.831 1.00124.33 C +ATOM 15793 C LYS I 73 49.522 -27.316 2.717 1.00114.76 C +ATOM 15794 O LYS I 73 49.923 -26.828 1.656 1.00127.72 O +ATOM 15795 CB LYS I 73 50.136 -26.334 4.887 1.00129.30 C +ATOM 15796 CG LYS I 73 51.373 -25.566 4.419 1.00128.74 C +ATOM 15797 CD LYS I 73 52.444 -25.486 5.514 1.00142.09 C +ATOM 15798 CE LYS I 73 53.848 -25.365 4.935 1.00162.41 C +ATOM 15799 NZ LYS I 73 54.502 -24.057 5.223 1.00165.57 N +ATOM 15800 N ASP I 74 49.466 -28.625 2.945 1.00111.62 N +ATOM 15801 CA ASP I 74 49.945 -29.589 1.952 1.00132.78 C +ATOM 15802 C ASP I 74 49.188 -29.486 0.622 1.00140.03 C +ATOM 15803 O ASP I 74 49.749 -29.785 -0.442 1.00139.30 O +ATOM 15804 CB ASP I 74 49.839 -31.017 2.493 1.00122.34 C +ATOM 15805 CG ASP I 74 50.814 -31.299 3.641 1.00117.16 C +ATOM 15806 OD1 ASP I 74 51.903 -30.678 3.717 1.00114.38 O +ATOM 15807 OD2 ASP I 74 50.475 -32.171 4.475 1.00120.73 O +ATOM 15808 N SER I 75 47.928 -29.046 0.688 1.00132.20 N +ATOM 15809 CA SER I 75 47.068 -28.941 -0.499 1.00135.24 C +ATOM 15810 C SER I 75 47.583 -27.920 -1.521 1.00126.84 C +ATOM 15811 O SER I 75 47.269 -28.010 -2.708 1.00104.88 O +ATOM 15812 CB SER I 75 45.637 -28.568 -0.096 1.00126.21 C +ATOM 15813 OG SER I 75 45.490 -27.163 0.023 1.00107.84 O +ATOM 15814 N ARG I 76 48.352 -26.949 -1.036 1.00132.02 N +ATOM 15815 CA ARG I 76 48.878 -25.853 -1.845 1.00127.19 C +ATOM 15816 C ARG I 76 47.744 -25.036 -2.421 1.00102.54 C +ATOM 15817 O ARG I 76 47.839 -24.503 -3.528 1.00 95.11 O +ATOM 15818 CB ARG I 76 49.788 -26.362 -2.953 1.00143.60 C +ATOM 15819 CG ARG I 76 51.023 -27.122 -2.470 1.00148.19 C +ATOM 15820 CD ARG I 76 51.877 -27.553 -3.663 1.00155.63 C +ATOM 15821 NE ARG I 76 51.231 -28.593 -4.465 1.00150.68 N +ATOM 15822 CZ ARG I 76 50.463 -28.383 -5.537 1.00139.00 C +ATOM 15823 NH1 ARG I 76 50.241 -27.155 -6.007 1.00125.24 N +ATOM 15824 NH2 ARG I 76 49.896 -29.419 -6.141 1.00137.67 N +ATOM 15825 N TRP I 77 46.699 -24.882 -1.613 1.00 90.86 N +ATOM 15826 CA TRP I 77 45.621 -23.938 -1.890 1.00 99.09 C +ATOM 15827 C TRP I 77 45.556 -22.819 -0.841 1.00 88.51 C +ATOM 15828 O TRP I 77 45.200 -21.677 -1.154 1.00 59.47 O +ATOM 15829 CB TRP I 77 44.298 -24.690 -1.911 1.00111.02 C +ATOM 15830 CG TRP I 77 43.907 -25.177 -3.258 1.00112.33 C +ATOM 15831 CD1 TRP I 77 44.404 -26.267 -3.911 1.00125.99 C +ATOM 15832 CD2 TRP I 77 42.891 -24.633 -4.098 1.00 96.69 C +ATOM 15833 NE1 TRP I 77 43.757 -26.434 -5.105 1.00124.98 N +ATOM 15834 CE2 TRP I 77 42.822 -25.441 -5.243 1.00107.28 C +ATOM 15835 CE3 TRP I 77 42.025 -23.546 -3.989 1.00 96.66 C +ATOM 15836 CZ2 TRP I 77 41.933 -25.187 -6.279 1.00110.99 C +ATOM 15837 CZ3 TRP I 77 41.124 -23.312 -5.012 1.00108.36 C +ATOM 15838 CH2 TRP I 77 41.091 -24.121 -6.144 1.00105.55 C +ATOM 15839 N PHE I 78 45.920 -23.163 0.395 1.00100.22 N +ATOM 15840 CA PHE I 78 45.798 -22.263 1.541 1.00108.26 C +ATOM 15841 C PHE I 78 47.144 -21.983 2.241 1.00120.41 C +ATOM 15842 O PHE I 78 47.985 -22.864 2.366 1.00101.44 O +ATOM 15843 CB PHE I 78 44.889 -22.896 2.569 1.00 97.23 C +ATOM 15844 CG PHE I 78 43.572 -23.292 2.030 1.00 92.71 C +ATOM 15845 CD1 PHE I 78 42.607 -22.325 1.750 1.00 95.49 C +ATOM 15846 CD2 PHE I 78 43.268 -24.632 1.835 1.00 76.31 C +ATOM 15847 CE1 PHE I 78 41.362 -22.696 1.268 1.00102.70 C +ATOM 15848 CE2 PHE I 78 42.022 -25.007 1.362 1.00 74.11 C +ATOM 15849 CZ PHE I 78 41.069 -24.042 1.073 1.00 76.75 C +ATOM 15850 N ILE I 79 47.307 -20.749 2.701 1.00112.05 N +ATOM 15851 CA ILE I 79 48.323 -20.388 3.665 1.00 79.12 C +ATOM 15852 C ILE I 79 47.619 -20.374 5.008 1.00 86.68 C +ATOM 15853 O ILE I 79 46.599 -19.684 5.202 1.00 86.55 O +ATOM 15854 CB ILE I 79 48.842 -18.969 3.415 1.00 99.21 C +ATOM 15855 CG1 ILE I 79 49.217 -18.784 1.946 1.00101.67 C +ATOM 15856 CG2 ILE I 79 50.042 -18.661 4.305 1.00121.28 C +ATOM 15857 CD1 ILE I 79 49.208 -17.331 1.479 1.00 93.05 C +ATOM 15858 N PRO I 80 48.114 -21.177 5.936 1.00 99.37 N +ATOM 15859 CA PRO I 80 47.500 -21.103 7.244 1.00107.84 C +ATOM 15860 C PRO I 80 48.143 -20.030 8.107 1.00 89.98 C +ATOM 15861 O PRO I 80 49.355 -19.960 8.194 1.00 59.25 O +ATOM 15862 CB PRO I 80 47.732 -22.516 7.820 1.00 91.80 C +ATOM 15863 CG PRO I 80 47.936 -23.362 6.623 1.00 82.28 C +ATOM 15864 CD PRO I 80 48.750 -22.478 5.727 1.00 93.15 C +ATOM 15865 N LEU I 81 47.308 -19.223 8.747 1.00 93.06 N +ATOM 15866 CA LEU I 81 47.765 -18.284 9.749 1.00 86.86 C +ATOM 15867 C LEU I 81 47.642 -18.877 11.140 1.00 87.55 C +ATOM 15868 O LEU I 81 46.719 -19.694 11.415 1.00121.79 O +ATOM 15869 CB LEU I 81 46.944 -17.034 9.653 1.00 99.08 C +ATOM 15870 CG LEU I 81 46.948 -16.490 8.227 1.00135.32 C +ATOM 15871 CD1 LEU I 81 46.021 -15.308 8.174 1.00127.82 C +ATOM 15872 CD2 LEU I 81 48.347 -16.083 7.834 1.00172.11 C +ATOM 15873 N GLU I 82 48.640 -18.575 11.960 1.00 75.04 N +ATOM 15874 CA GLU I 82 48.795 -19.252 13.253 1.00113.56 C +ATOM 15875 C GLU I 82 47.887 -18.578 14.250 1.00125.13 C +ATOM 15876 O GLU I 82 48.148 -17.448 14.686 1.00143.02 O +ATOM 15877 CB GLU I 82 50.268 -19.262 13.762 1.00133.30 C +ATOM 15878 CG GLU I 82 50.499 -19.879 15.159 1.00111.28 C +ATOM 15879 CD GLU I 82 50.326 -21.410 15.230 1.00113.13 C +ATOM 15880 OE1 GLU I 82 49.300 -21.973 14.722 1.00191.41 O +ATOM 15881 OE2 GLU I 82 51.191 -22.072 15.836 1.00 69.15 O +ATOM 15882 N ARG I 83 46.873 -19.332 14.665 1.00109.95 N +ATOM 15883 CA ARG I 83 45.985 -18.913 15.728 1.00 95.95 C +ATOM 15884 C ARG I 83 45.903 -19.924 16.885 1.00 84.48 C +ATOM 15885 O ARG I 83 45.511 -19.561 17.991 1.00 92.93 O +ATOM 15886 CB ARG I 83 44.593 -18.639 15.153 1.00 91.76 C +ATOM 15887 CG ARG I 83 44.561 -17.615 14.031 1.00 70.70 C +ATOM 15888 CD ARG I 83 44.874 -16.212 14.505 1.00 55.10 C +ATOM 15889 NE ARG I 83 44.567 -15.291 13.429 1.00 50.72 N +ATOM 15890 CZ ARG I 83 45.454 -14.744 12.619 1.00 61.97 C +ATOM 15891 NH1 ARG I 83 46.766 -14.940 12.816 1.00 77.62 N +ATOM 15892 NH2 ARG I 83 45.037 -14.016 11.574 1.00 51.99 N +ATOM 15893 N GLN I 84 46.256 -21.183 16.665 1.00 86.02 N +ATOM 15894 CA GLN I 84 46.233 -22.133 17.796 1.00 99.11 C +ATOM 15895 C GLN I 84 47.105 -21.626 18.948 1.00 91.34 C +ATOM 15896 O GLN I 84 46.732 -21.712 20.097 1.00 82.28 O +ATOM 15897 CB GLN I 84 46.646 -23.557 17.379 1.00120.13 C +ATOM 15898 CG GLN I 84 45.965 -24.667 18.172 1.00115.80 C +ATOM 15899 CD GLN I 84 46.472 -26.052 17.788 1.00164.39 C +ATOM 15900 OE1 GLN I 84 46.759 -26.324 16.620 1.00220.49 O +ATOM 15901 NE2 GLN I 84 46.555 -26.947 18.768 1.00176.06 N +ATOM 15902 N GLY I 85 48.269 -21.072 18.646 1.00100.51 N +ATOM 15903 CA GLY I 85 49.120 -20.582 19.717 1.00104.51 C +ATOM 15904 C GLY I 85 49.204 -19.074 19.720 1.00 97.23 C +ATOM 15905 O GLY I 85 50.277 -18.517 19.971 1.00 95.03 O +ATOM 15906 N LEU I 86 48.081 -18.406 19.456 1.00 87.81 N +ATOM 15907 CA LEU I 86 48.092 -16.962 19.177 1.00 96.11 C +ATOM 15908 C LEU I 86 48.695 -16.162 20.344 1.00 87.68 C +ATOM 15909 O LEU I 86 49.392 -15.166 20.125 1.00 78.19 O +ATOM 15910 CB LEU I 86 46.679 -16.446 18.861 1.00 83.38 C +ATOM 15911 CG LEU I 86 46.440 -14.943 18.718 1.00 92.09 C +ATOM 15912 CD1 LEU I 86 47.258 -14.317 17.598 1.00117.33 C +ATOM 15913 CD2 LEU I 86 44.959 -14.685 18.486 1.00 84.32 C +ATOM 15914 N GLN I 87 48.491 -16.648 21.562 1.00 81.24 N +ATOM 15915 CA GLN I 87 48.906 -15.903 22.736 1.00103.58 C +ATOM 15916 C GLN I 87 50.438 -15.746 22.778 1.00113.05 C +ATOM 15917 O GLN I 87 50.983 -14.658 23.049 1.00107.16 O +ATOM 15918 CB GLN I 87 48.360 -16.579 24.000 1.00112.91 C +ATOM 15919 CG GLN I 87 48.022 -15.603 25.126 1.00121.49 C +ATOM 15920 CD GLN I 87 47.277 -14.346 24.663 1.00124.64 C +ATOM 15921 OE1 GLN I 87 46.220 -14.426 24.028 1.00121.31 O +ATOM 15922 NE2 GLN I 87 47.842 -13.176 24.961 1.00120.71 N +ATOM 15923 N ASN I 88 51.135 -16.829 22.452 1.00 96.72 N +ATOM 15924 CA ASN I 88 52.595 -16.812 22.426 1.00 85.20 C +ATOM 15925 C ASN I 88 53.138 -15.884 21.356 1.00 79.43 C +ATOM 15926 O ASN I 88 54.204 -15.272 21.490 1.00 60.08 O +ATOM 15927 CB ASN I 88 53.108 -18.213 22.163 1.00 82.39 C +ATOM 15928 CG ASN I 88 52.580 -19.196 23.161 1.00 91.72 C +ATOM 15929 OD1 ASN I 88 52.497 -18.880 24.354 1.00 61.56 O +ATOM 15930 ND2 ASN I 88 52.278 -20.416 22.705 1.00106.82 N +ATOM 15931 N LEU I 89 52.428 -15.862 20.242 1.00 87.64 N +ATOM 15932 CA LEU I 89 52.831 -15.072 19.101 1.00 81.27 C +ATOM 15933 C LEU I 89 52.817 -13.608 19.561 1.00 66.17 C +ATOM 15934 O LEU I 89 53.710 -12.828 19.231 1.00 48.78 O +ATOM 15935 CB LEU I 89 51.868 -15.374 17.920 1.00 89.77 C +ATOM 15936 CG LEU I 89 52.351 -15.253 16.482 1.00 90.26 C +ATOM 15937 CD1 LEU I 89 51.613 -14.124 15.791 1.00101.55 C +ATOM 15938 CD2 LEU I 89 53.849 -14.998 16.424 1.00122.95 C +ATOM 15939 N LEU I 90 51.769 -13.248 20.300 1.00 79.61 N +ATOM 15940 CA LEU I 90 51.556 -11.857 20.686 1.00 74.62 C +ATOM 15941 C LEU I 90 52.570 -11.482 21.741 1.00 71.34 C +ATOM 15942 O LEU I 90 53.014 -10.327 21.826 1.00 53.49 O +ATOM 15943 CB LEU I 90 50.145 -11.674 21.209 1.00 69.73 C +ATOM 15944 CG LEU I 90 49.043 -11.973 20.190 1.00 69.78 C +ATOM 15945 CD1 LEU I 90 47.737 -12.184 20.923 1.00 90.97 C +ATOM 15946 CD2 LEU I 90 48.939 -10.812 19.218 1.00 80.32 C +ATOM 15947 N ASN I 91 52.974 -12.484 22.518 1.00 70.68 N +ATOM 15948 CA ASN I 91 54.000 -12.296 23.544 1.00 87.84 C +ATOM 15949 C ASN I 91 55.392 -12.036 22.944 1.00 73.30 C +ATOM 15950 O ASN I 91 56.065 -11.072 23.310 1.00 56.28 O +ATOM 15951 CB ASN I 91 54.050 -13.538 24.425 1.00110.52 C +ATOM 15952 CG ASN I 91 53.664 -13.301 25.863 1.00113.95 C +ATOM 15953 OD1 ASN I 91 52.965 -12.347 26.208 1.00 88.09 O +ATOM 15954 ND2 ASN I 91 54.090 -14.234 26.709 1.00117.98 N +ATOM 15955 N GLU I 92 55.800 -12.872 21.991 1.00 74.40 N +ATOM 15956 CA GLU I 92 57.059 -12.621 21.262 1.00 71.64 C +ATOM 15957 C GLU I 92 57.074 -11.234 20.596 1.00 66.80 C +ATOM 15958 O GLU I 92 58.102 -10.557 20.542 1.00 68.61 O +ATOM 15959 CB GLU I 92 57.330 -13.702 20.209 1.00 57.42 C +ATOM 15960 CG GLU I 92 58.143 -14.881 20.725 1.00 59.25 C +ATOM 15961 CD GLU I 92 59.519 -14.491 21.355 1.00 64.58 C +ATOM 15962 OE1 GLU I 92 60.336 -13.798 20.752 1.00 57.18 O +ATOM 15963 OE2 GLU I 92 59.780 -14.818 22.499 1.00 45.32 O +ATOM 15964 N ARG I 93 55.910 -10.794 20.134 1.00 76.20 N +ATOM 15965 CA ARG I 93 55.787 -9.488 19.510 1.00 80.83 C +ATOM 15966 C ARG I 93 55.875 -8.361 20.547 1.00 82.95 C +ATOM 15967 O ARG I 93 56.492 -7.317 20.284 1.00 94.78 O +ATOM 15968 CB ARG I 93 54.500 -9.422 18.670 1.00 64.74 C +ATOM 15969 CG ARG I 93 54.585 -10.318 17.429 1.00 46.11 C +ATOM 15970 CD ARG I 93 53.280 -10.553 16.762 1.00 36.97 C +ATOM 15971 NE ARG I 93 53.154 -9.688 15.587 1.00 39.37 N +ATOM 15972 CZ ARG I 93 52.486 -8.532 15.546 1.00 46.21 C +ATOM 15973 NH1 ARG I 93 51.910 -8.008 16.646 1.00 48.27 N +ATOM 15974 NH2 ARG I 93 52.361 -7.899 14.392 1.00 50.41 N +ATOM 15975 N LYS I 94 55.394 -8.617 21.752 1.00 79.68 N +ATOM 15976 CA LYS I 94 55.643 -7.684 22.849 1.00107.81 C +ATOM 15977 C LYS I 94 57.143 -7.539 23.129 1.00 99.62 C +ATOM 15978 O LYS I 94 57.637 -6.432 23.400 1.00 84.21 O +ATOM 15979 CB LYS I 94 54.941 -8.146 24.127 1.00126.31 C +ATOM 15980 CG LYS I 94 53.497 -7.690 24.265 1.00149.47 C +ATOM 15981 CD LYS I 94 52.843 -8.369 25.460 1.00146.94 C +ATOM 15982 CE LYS I 94 51.602 -7.637 25.954 1.00138.23 C +ATOM 15983 NZ LYS I 94 50.820 -8.514 26.865 1.00135.99 N +ATOM 15984 N ILE I 95 57.851 -8.668 23.123 1.00 87.01 N +ATOM 15985 CA ILE I 95 59.259 -8.665 23.506 1.00 75.87 C +ATOM 15986 C ILE I 95 60.085 -7.954 22.459 1.00 64.92 C +ATOM 15987 O ILE I 95 61.052 -7.249 22.785 1.00 61.95 O +ATOM 15988 CB ILE I 95 59.841 -10.080 23.725 1.00 77.53 C +ATOM 15989 CG1 ILE I 95 58.938 -10.912 24.629 1.00 65.22 C +ATOM 15990 CG2 ILE I 95 61.201 -9.942 24.390 1.00 98.67 C +ATOM 15991 CD1 ILE I 95 59.580 -12.167 25.171 1.00 67.09 C +ATOM 15992 N ILE I 96 59.734 -8.222 21.205 1.00 68.65 N +ATOM 15993 CA ILE I 96 60.322 -7.538 20.076 1.00 79.02 C +ATOM 15994 C ILE I 96 60.153 -6.047 20.283 1.00 73.63 C +ATOM 15995 O ILE I 96 61.139 -5.313 20.277 1.00103.52 O +ATOM 15996 CB ILE I 96 59.690 -7.948 18.713 1.00 84.22 C +ATOM 15997 CG1 ILE I 96 60.021 -9.405 18.379 1.00 76.55 C +ATOM 15998 CG2 ILE I 96 60.234 -7.071 17.599 1.00 73.17 C +ATOM 15999 CD1 ILE I 96 59.483 -9.849 17.040 1.00 60.46 C +ATOM 16000 N ARG I 97 58.912 -5.593 20.400 1.00 63.77 N +ATOM 16001 CA ARG I 97 58.635 -4.150 20.441 1.00 76.46 C +ATOM 16002 C ARG I 97 59.338 -3.505 21.636 1.00 90.07 C +ATOM 16003 O ARG I 97 59.723 -2.327 21.589 1.00 81.02 O +ATOM 16004 CB ARG I 97 57.129 -3.878 20.517 1.00 75.82 C +ATOM 16005 CG ARG I 97 56.499 -3.393 19.228 1.00 72.62 C +ATOM 16006 CD ARG I 97 55.019 -3.099 19.408 1.00 76.62 C +ATOM 16007 NE ARG I 97 54.201 -4.323 19.343 1.00 93.90 N +ATOM 16008 CZ ARG I 97 53.527 -4.738 18.265 1.00109.64 C +ATOM 16009 NH1 ARG I 97 53.567 -4.049 17.115 1.00 96.98 N +ATOM 16010 NH2 ARG I 97 52.807 -5.858 18.331 1.00120.34 N +ATOM 16011 N ALA I 98 59.510 -4.279 22.704 1.00 80.12 N +ATOM 16012 CA ALA I 98 60.189 -3.774 23.878 1.00 87.32 C +ATOM 16013 C ALA I 98 61.695 -3.705 23.652 1.00 80.89 C +ATOM 16014 O ALA I 98 62.390 -2.854 24.234 1.00 75.25 O +ATOM 16015 CB ALA I 98 59.871 -4.654 25.067 1.00 97.77 C +ATOM 16016 N ALA I 99 62.178 -4.574 22.772 1.00 75.12 N +ATOM 16017 CA ALA I 99 63.597 -4.627 22.437 1.00 82.66 C +ATOM 16018 C ALA I 99 64.057 -3.413 21.640 1.00 72.57 C +ATOM 16019 O ALA I 99 65.058 -2.773 21.971 1.00 85.68 O +ATOM 16020 CB ALA I 99 63.907 -5.897 21.652 1.00115.61 C +ATOM 16021 N GLN I 100 63.326 -3.103 20.585 1.00 64.08 N +ATOM 16022 CA GLN I 100 63.830 -2.191 19.567 1.00 79.76 C +ATOM 16023 C GLN I 100 63.184 -0.818 19.584 1.00 82.54 C +ATOM 16024 O GLN I 100 63.437 0.004 18.698 1.00102.23 O +ATOM 16025 CB GLN I 100 63.686 -2.820 18.171 1.00100.89 C +ATOM 16026 CG GLN I 100 62.367 -3.528 17.905 1.00108.29 C +ATOM 16027 CD GLN I 100 62.485 -4.639 16.866 1.00102.07 C +ATOM 16028 OE1 GLN I 100 63.239 -5.626 17.040 1.00 70.03 O +ATOM 16029 NE2 GLN I 100 61.697 -4.506 15.805 1.00 83.03 N +ATOM 16030 N GLU I 101 62.369 -0.554 20.595 1.00101.43 N +ATOM 16031 CA GLU I 101 61.677 0.734 20.691 1.00117.26 C +ATOM 16032 C GLU I 101 62.629 1.913 20.927 1.00112.53 C +ATOM 16033 O GLU I 101 62.298 3.055 20.600 1.00 86.94 O +ATOM 16034 CB GLU I 101 60.597 0.695 21.780 1.00121.42 C +ATOM 16035 CG GLU I 101 61.085 0.218 23.143 1.00125.33 C +ATOM 16036 CD GLU I 101 60.002 0.283 24.208 1.00114.39 C +ATOM 16037 OE1 GLU I 101 58.817 0.359 23.835 1.00125.04 O +ATOM 16038 OE2 GLU I 101 60.329 0.232 25.416 1.00103.86 O +ATOM 16039 N ASN I 102 63.807 1.642 21.483 1.00102.17 N +ATOM 16040 CA ASN I 102 64.750 2.712 21.791 1.00112.68 C +ATOM 16041 C ASN I 102 65.751 2.996 20.673 1.00138.92 C +ATOM 16042 O ASN I 102 66.612 3.859 20.812 1.00142.72 O +ATOM 16043 CB ASN I 102 65.487 2.389 23.082 1.00118.34 C +ATOM 16044 CG ASN I 102 64.596 2.514 24.282 1.00134.01 C +ATOM 16045 OD1 ASN I 102 64.325 3.624 24.766 1.00132.66 O +ATOM 16046 ND2 ASN I 102 64.090 1.372 24.757 1.00149.44 N +ATOM 16047 N GLY I 103 65.697 2.212 19.602 1.00147.29 N +ATOM 16048 CA GLY I 103 66.662 2.353 18.508 1.00131.66 C +ATOM 16049 C GLY I 103 68.123 2.146 18.888 1.00117.33 C +ATOM 16050 O GLY I 103 69.017 2.817 18.376 1.00146.65 O +ATOM 16051 N THR I 104 68.364 1.248 19.829 1.00119.63 N +ATOM 16052 CA THR I 104 69.716 0.834 20.139 1.00130.47 C +ATOM 16053 C THR I 104 69.979 -0.506 19.502 1.00120.30 C +ATOM 16054 O THR I 104 71.110 -0.799 19.159 1.00 93.08 O +ATOM 16055 CB THR I 104 69.988 0.751 21.667 1.00154.20 C +ATOM 16056 OG1 THR I 104 69.174 -0.260 22.278 1.00138.33 O +ATOM 16057 CG2 THR I 104 69.723 2.108 22.341 1.00144.45 C +ATOM 16058 N VAL I 105 68.930 -1.299 19.291 1.00158.99 N +ATOM 16059 CA VAL I 105 69.120 -2.673 18.803 1.00191.41 C +ATOM 16060 C VAL I 105 69.843 -2.673 17.451 1.00208.22 C +ATOM 16061 O VAL I 105 69.582 -1.816 16.584 1.00120.68 O +ATOM 16062 CB VAL I 105 67.797 -3.503 18.748 1.00170.21 C +ATOM 16063 CG1 VAL I 105 67.794 -4.505 17.593 1.00140.34 C +ATOM 16064 CG2 VAL I 105 67.570 -4.236 20.067 1.00135.45 C +ATOM 16065 N ALA I 106 70.758 -3.637 17.309 1.00216.54 N +ATOM 16066 CA ALA I 106 71.671 -3.721 16.174 1.00193.48 C +ATOM 16067 C ALA I 106 70.901 -3.911 14.872 1.00196.94 C +ATOM 16068 O ALA I 106 69.983 -4.735 14.794 1.00286.57 O +ATOM 16069 CB ALA I 106 72.656 -4.865 16.378 1.00154.55 C +ATOM 16070 N ILE I 107 71.268 -3.129 13.861 1.00156.00 N +ATOM 16071 CA ILE I 107 70.529 -3.087 12.599 1.00134.38 C +ATOM 16072 C ILE I 107 70.431 -4.472 11.920 1.00113.36 C +ATOM 16073 O ILE I 107 69.462 -4.768 11.213 1.00 88.92 O +ATOM 16074 CB ILE I 107 71.161 -2.041 11.645 1.00137.21 C +ATOM 16075 CG1 ILE I 107 70.240 -1.754 10.452 1.00144.48 C +ATOM 16076 CG2 ILE I 107 72.537 -2.502 11.165 1.00144.01 C +ATOM 16077 CD1 ILE I 107 68.848 -1.268 10.819 1.00117.84 C +ATOM 16078 N ASN I 108 71.446 -5.310 12.124 1.00137.53 N +ATOM 16079 CA ASN I 108 71.452 -6.694 11.610 1.00146.65 C +ATOM 16080 C ASN I 108 70.452 -7.561 12.367 1.00147.10 C +ATOM 16081 O ASN I 108 69.824 -8.451 11.801 1.00147.72 O +ATOM 16082 CB ASN I 108 72.841 -7.327 11.755 1.00142.47 C +ATOM 16083 CG ASN I 108 73.962 -6.307 11.651 1.00165.78 C +ATOM 16084 OD1 ASN I 108 74.421 -5.986 10.558 1.00170.34 O +ATOM 16085 ND2 ASN I 108 74.395 -5.778 12.797 1.00161.25 N +ATOM 16086 N ASN I 109 70.307 -7.271 13.655 1.00141.23 N +ATOM 16087 CA ASN I 109 69.476 -8.067 14.551 1.00128.82 C +ATOM 16088 C ASN I 109 68.007 -7.637 14.558 1.00117.25 C +ATOM 16089 O ASN I 109 67.139 -8.382 15.007 1.00116.00 O +ATOM 16090 CB ASN I 109 70.042 -7.991 15.970 1.00139.99 C +ATOM 16091 CG ASN I 109 70.518 -9.337 16.470 1.00157.49 C +ATOM 16092 OD1 ASN I 109 69.953 -9.893 17.406 1.00162.62 O +ATOM 16093 ND2 ASN I 109 71.539 -9.886 15.820 1.00179.67 N +ATOM 16094 N ARG I 110 67.745 -6.432 14.049 1.00 97.68 N +ATOM 16095 CA ARG I 110 66.422 -5.800 14.105 1.00 77.58 C +ATOM 16096 C ARG I 110 65.363 -6.692 13.468 1.00 91.53 C +ATOM 16097 O ARG I 110 65.567 -7.227 12.363 1.00 98.92 O +ATOM 16098 CB ARG I 110 66.479 -4.453 13.351 1.00 87.44 C +ATOM 16099 CG ARG I 110 65.419 -3.440 13.752 1.00 94.52 C +ATOM 16100 CD ARG I 110 65.935 -2.006 13.685 1.00 92.54 C +ATOM 16101 NE ARG I 110 65.757 -1.389 12.360 1.00 96.74 N +ATOM 16102 CZ ARG I 110 65.024 -0.287 12.113 1.00114.13 C +ATOM 16103 NH1 ARG I 110 64.395 0.362 13.095 1.00111.01 N +ATOM 16104 NH2 ARG I 110 64.935 0.187 10.876 1.00102.91 N +ATOM 16105 N ILE I 111 64.214 -6.831 14.128 1.00105.69 N +ATOM 16106 CA ILE I 111 63.061 -7.546 13.524 1.00104.69 C +ATOM 16107 C ILE I 111 61.944 -6.583 13.145 1.00 96.09 C +ATOM 16108 O ILE I 111 61.395 -5.946 14.015 1.00 76.08 O +ATOM 16109 CB ILE I 111 62.474 -8.599 14.476 1.00 89.10 C +ATOM 16110 CG1 ILE I 111 63.543 -9.667 14.750 1.00121.06 C +ATOM 16111 CG2 ILE I 111 61.234 -9.230 13.865 1.00 70.56 C +ATOM 16112 CD1 ILE I 111 63.214 -10.603 15.890 1.00134.29 C +ATOM 16113 N PRO I 112 61.624 -6.469 11.842 1.00 98.46 N +ATOM 16114 CA PRO I 112 60.618 -5.510 11.397 1.00 93.49 C +ATOM 16115 C PRO I 112 59.221 -6.077 11.595 1.00113.59 C +ATOM 16116 O PRO I 112 58.972 -7.250 11.234 1.00107.60 O +ATOM 16117 CB PRO I 112 60.919 -5.358 9.917 1.00101.74 C +ATOM 16118 CG PRO I 112 61.474 -6.693 9.513 1.00120.73 C +ATOM 16119 CD PRO I 112 62.134 -7.293 10.727 1.00115.96 C +ATOM 16120 N LEU I 113 58.352 -5.292 12.244 1.00129.59 N +ATOM 16121 CA LEU I 113 57.038 -5.784 12.697 1.00112.36 C +ATOM 16122 C LEU I 113 55.907 -5.189 11.922 1.00103.45 C +ATOM 16123 O LEU I 113 55.921 -4.011 11.533 1.00 94.84 O +ATOM 16124 CB LEU I 113 56.791 -5.500 14.166 1.00106.14 C +ATOM 16125 CG LEU I 113 57.314 -6.561 15.132 1.00128.57 C +ATOM 16126 CD1 LEU I 113 56.897 -6.154 16.524 1.00123.20 C +ATOM 16127 CD2 LEU I 113 56.821 -7.968 14.820 1.00113.49 C +ATOM 16128 N GLN I 114 54.973 -6.070 11.608 1.00 92.87 N +ATOM 16129 CA GLN I 114 53.989 -5.819 10.574 1.00 96.94 C +ATOM 16130 C GLN I 114 52.766 -6.417 11.166 1.00 83.38 C +ATOM 16131 O GLN I 114 52.851 -7.380 11.932 1.00 80.19 O +ATOM 16132 CB GLN I 114 54.346 -6.514 9.239 1.00105.56 C +ATOM 16133 CG GLN I 114 53.860 -5.795 7.957 1.00 94.07 C +ATOM 16134 CD GLN I 114 53.811 -6.719 6.678 1.00111.92 C +ATOM 16135 OE1 GLN I 114 53.221 -6.406 5.602 1.00 66.32 O +ATOM 16136 NE2 GLN I 114 54.476 -7.855 6.798 1.00111.24 N +ATOM 16137 N SER I 115 51.634 -5.796 10.868 1.00 80.14 N +ATOM 16138 CA SER I 115 50.381 -6.180 11.484 1.00 87.32 C +ATOM 16139 C SER I 115 50.121 -7.645 11.202 1.00 82.10 C +ATOM 16140 O SER I 115 50.647 -8.189 10.194 1.00 85.26 O +ATOM 16141 CB SER I 115 49.241 -5.319 10.935 1.00107.94 C +ATOM 16142 OG SER I 115 49.225 -5.319 9.493 1.00 86.28 O +ATOM 16143 N LEU I 116 49.346 -8.303 12.074 1.00 63.62 N +ATOM 16144 CA LEU I 116 49.226 -9.743 11.930 1.00 73.35 C +ATOM 16145 C LEU I 116 48.377 -10.039 10.691 1.00 92.95 C +ATOM 16146 O LEU I 116 47.319 -9.447 10.531 1.00 82.72 O +ATOM 16147 CB LEU I 116 48.590 -10.383 13.127 1.00 60.59 C +ATOM 16148 CG LEU I 116 49.385 -10.317 14.404 1.00 55.58 C +ATOM 16149 CD1 LEU I 116 48.936 -9.087 15.231 1.00 66.20 C +ATOM 16150 CD2 LEU I 116 49.182 -11.607 15.181 1.00 42.62 C +ATOM 16151 N THR I 117 48.923 -10.835 9.761 1.00112.32 N +ATOM 16152 CA THR I 117 48.254 -11.153 8.489 1.00 88.75 C +ATOM 16153 C THR I 117 46.939 -11.778 8.812 1.00 87.63 C +ATOM 16154 O THR I 117 46.864 -12.593 9.735 1.00 82.29 O +ATOM 16155 CB THR I 117 49.032 -12.178 7.665 1.00 81.76 C +ATOM 16156 OG1 THR I 117 50.368 -11.716 7.452 1.00108.60 O +ATOM 16157 CG2 THR I 117 48.360 -12.393 6.330 1.00 85.67 C +ATOM 16158 N ALA I 118 45.893 -11.309 8.142 1.00 93.01 N +ATOM 16159 CA ALA I 118 44.535 -11.610 8.567 1.00110.50 C +ATOM 16160 C ALA I 118 43.839 -12.442 7.526 1.00101.02 C +ATOM 16161 O ALA I 118 43.908 -12.141 6.333 1.00 82.63 O +ATOM 16162 CB ALA I 118 43.737 -10.336 8.839 1.00119.43 C +ATOM 16163 N ALA I 119 43.050 -13.394 8.016 1.00 86.45 N +ATOM 16164 CA ALA I 119 42.369 -14.372 7.170 1.00 78.34 C +ATOM 16165 C ALA I 119 41.043 -13.880 6.665 1.00 71.63 C +ATOM 16166 O ALA I 119 40.391 -13.030 7.317 1.00 68.30 O +ATOM 16167 CB ALA I 119 42.168 -15.650 7.951 1.00 87.54 C +ATOM 16168 N ASN I 120 40.594 -14.435 5.542 1.00 95.79 N +ATOM 16169 CA ASN I 120 39.238 -14.113 5.057 1.00137.73 C +ATOM 16170 C ASN I 120 38.192 -15.174 5.407 1.00 98.79 C +ATOM 16171 O ASN I 120 37.081 -14.862 5.822 1.00 77.08 O +ATOM 16172 CB ASN I 120 39.200 -13.875 3.549 1.00145.57 C +ATOM 16173 CG ASN I 120 37.814 -13.426 3.071 1.00141.23 C +ATOM 16174 OD1 ASN I 120 37.346 -13.897 2.034 1.00171.85 O +ATOM 16175 ND2 ASN I 120 37.123 -12.562 3.856 1.00105.44 N +ATOM 16176 N ILE I 121 38.546 -16.421 5.192 1.00 69.22 N +ATOM 16177 CA ILE I 121 37.689 -17.488 5.609 1.00 54.93 C +ATOM 16178 C ILE I 121 38.407 -18.151 6.735 1.00 52.46 C +ATOM 16179 O ILE I 121 39.628 -18.308 6.727 1.00 70.08 O +ATOM 16180 CB ILE I 121 37.360 -18.484 4.453 1.00 63.63 C +ATOM 16181 CG1 ILE I 121 38.562 -19.357 4.056 1.00 56.88 C +ATOM 16182 CG2 ILE I 121 36.832 -17.731 3.232 1.00 71.48 C +ATOM 16183 CD1 ILE I 121 38.397 -20.797 4.432 1.00 55.41 C +ATOM 16184 N MET I 122 37.654 -18.594 7.705 1.00 51.86 N +ATOM 16185 CA MET I 122 38.225 -19.487 8.697 1.00 58.20 C +ATOM 16186 C MET I 122 37.396 -20.769 8.744 1.00 49.31 C +ATOM 16187 O MET I 122 36.198 -20.777 8.462 1.00 46.48 O +ATOM 16188 CB MET I 122 38.313 -18.809 10.066 1.00 67.24 C +ATOM 16189 CG MET I 122 36.992 -18.282 10.615 1.00 89.36 C +ATOM 16190 SD MET I 122 37.049 -18.175 12.406 1.00 70.90 S +ATOM 16191 CE MET I 122 35.410 -18.889 12.799 1.00124.29 C +ATOM 16192 N VAL I 123 38.070 -21.877 8.971 1.00 51.10 N +ATOM 16193 CA VAL I 123 37.425 -23.176 8.892 1.00 62.85 C +ATOM 16194 C VAL I 123 37.568 -23.821 10.226 1.00 61.91 C +ATOM 16195 O VAL I 123 38.681 -23.994 10.726 1.00 48.05 O +ATOM 16196 CB VAL I 123 38.016 -24.130 7.788 1.00 73.00 C +ATOM 16197 CG1 VAL I 123 39.526 -24.013 7.691 1.00 78.79 C +ATOM 16198 CG2 VAL I 123 37.597 -25.583 8.037 1.00 83.46 C +ATOM 16199 N GLU I 124 36.443 -24.241 10.784 1.00 83.60 N +ATOM 16200 CA GLU I 124 36.475 -25.042 12.011 1.00 98.39 C +ATOM 16201 C GLU I 124 35.698 -26.312 11.826 1.00 61.26 C +ATOM 16202 O GLU I 124 34.929 -26.442 10.884 1.00 75.04 O +ATOM 16203 CB GLU I 124 35.954 -24.233 13.212 1.00115.66 C +ATOM 16204 CG GLU I 124 34.927 -23.158 12.886 1.00102.33 C +ATOM 16205 CD GLU I 124 34.797 -22.171 14.021 1.00 98.14 C +ATOM 16206 OE1 GLU I 124 35.831 -21.816 14.648 1.00144.66 O +ATOM 16207 OE2 GLU I 124 33.689 -21.681 14.249 1.00 93.09 O +ATOM 16208 N GLY I 125 35.792 -27.173 12.813 1.00 42.22 N +ATOM 16209 CA GLY I 125 35.105 -28.428 12.752 1.00 40.46 C +ATOM 16210 C GLY I 125 35.170 -29.178 14.046 1.00 44.95 C +ATOM 16211 O GLY I 125 35.497 -28.614 15.114 1.00 55.47 O +ATOM 16212 N SER I 126 34.976 -30.485 13.967 1.00 47.71 N +ATOM 16213 CA SER I 126 34.946 -31.281 15.188 1.00 63.82 C +ATOM 16214 C SER I 126 35.165 -32.716 14.813 1.00 62.46 C +ATOM 16215 O SER I 126 34.670 -33.156 13.779 1.00 57.45 O +ATOM 16216 CB SER I 126 33.587 -31.113 15.921 1.00 83.14 C +ATOM 16217 OG SER I 126 32.999 -29.817 15.742 1.00 70.28 O +ATOM 16218 N ILE I 127 35.789 -33.475 15.697 1.00 63.54 N +ATOM 16219 CA ILE I 127 35.646 -34.911 15.625 1.00 92.72 C +ATOM 16220 C ILE I 127 34.258 -35.319 16.156 1.00106.44 C +ATOM 16221 O ILE I 127 34.040 -35.397 17.353 1.00160.33 O +ATOM 16222 CB ILE I 127 36.757 -35.652 16.384 1.00 84.75 C +ATOM 16223 CG1 ILE I 127 38.105 -35.328 15.735 1.00 85.43 C +ATOM 16224 CG2 ILE I 127 36.500 -37.174 16.381 1.00 71.71 C +ATOM 16225 CD1 ILE I 127 39.264 -35.345 16.714 1.00103.74 C +ATOM 16226 N ILE I 128 33.334 -35.594 15.234 1.00 88.69 N +ATOM 16227 CA ILE I 128 31.958 -36.046 15.547 1.00 63.24 C +ATOM 16228 C ILE I 128 31.959 -37.564 15.578 1.00 74.50 C +ATOM 16229 O ILE I 128 32.121 -38.244 14.537 1.00124.00 O +ATOM 16230 CB ILE I 128 30.969 -35.501 14.522 1.00 45.95 C +ATOM 16231 CG1 ILE I 128 31.411 -35.837 13.098 1.00 48.63 C +ATOM 16232 CG2 ILE I 128 30.990 -33.985 14.561 1.00 49.39 C +ATOM 16233 CD1 ILE I 128 30.269 -35.829 12.103 1.00 49.18 C +ATOM 16234 N GLY I 129 32.122 -38.092 16.781 1.00 71.33 N +ATOM 16235 CA GLY I 129 31.938 -39.504 16.981 1.00 81.89 C +ATOM 16236 C GLY I 129 33.179 -40.379 16.823 1.00 80.19 C +ATOM 16237 O GLY I 129 33.865 -40.365 15.771 1.00 79.50 O +ATOM 16238 N TYR I 130 33.271 -41.337 17.743 1.00 77.64 N +ATOM 16239 CA TYR I 130 33.997 -42.574 17.499 1.00 93.43 C +ATOM 16240 C TYR I 130 33.166 -43.691 18.090 1.00104.03 C +ATOM 16241 O TYR I 130 32.994 -43.766 19.293 1.00 92.73 O +ATOM 16242 CB TYR I 130 35.345 -42.478 18.186 1.00112.14 C +ATOM 16243 CG TYR I 130 36.217 -43.734 18.166 1.00112.45 C +ATOM 16244 CD1 TYR I 130 35.962 -44.805 19.028 1.00109.68 C +ATOM 16245 CD2 TYR I 130 37.371 -43.778 17.390 1.00 96.53 C +ATOM 16246 CE1 TYR I 130 36.764 -45.932 19.035 1.00 81.98 C +ATOM 16247 CE2 TYR I 130 38.183 -44.891 17.399 1.00 89.88 C +ATOM 16248 CZ TYR I 130 37.854 -45.971 18.198 1.00 84.52 C +ATOM 16249 OH TYR I 130 38.683 -47.051 18.186 1.00134.11 O +ATOM 16250 N GLU I 131 32.586 -44.532 17.238 1.00118.73 N +ATOM 16251 CA GLU I 131 31.923 -45.742 17.717 1.00118.51 C +ATOM 16252 C GLU I 131 32.880 -46.915 17.590 1.00 88.67 C +ATOM 16253 O GLU I 131 33.734 -46.930 16.695 1.00 62.70 O +ATOM 16254 CB GLU I 131 30.652 -45.984 16.917 1.00158.31 C +ATOM 16255 CG GLU I 131 29.743 -47.078 17.452 1.00173.11 C +ATOM 16256 CD GLU I 131 28.757 -46.593 18.507 1.00159.61 C +ATOM 16257 OE1 GLU I 131 28.379 -45.388 18.481 1.00147.56 O +ATOM 16258 OE2 GLU I 131 28.338 -47.434 19.340 1.00136.64 O +ATOM 16259 N SER I 132 32.801 -47.855 18.531 1.00 80.03 N +ATOM 16260 CA SER I 132 33.802 -48.927 18.614 1.00 87.04 C +ATOM 16261 C SER I 132 33.209 -50.321 18.413 1.00 88.63 C +ATOM 16262 O SER I 132 32.101 -50.605 18.889 1.00 99.80 O +ATOM 16263 CB SER I 132 34.523 -48.861 19.952 1.00 78.45 C +ATOM 16264 OG SER I 132 34.216 -49.987 20.754 1.00 75.01 O +ATOM 16265 N ASN I 133 33.951 -51.181 17.718 1.00 75.43 N +ATOM 16266 CA ASN I 133 33.416 -52.457 17.258 1.00 91.30 C +ATOM 16267 C ASN I 133 32.050 -52.282 16.622 1.00103.18 C +ATOM 16268 O ASN I 133 31.069 -52.940 17.000 1.00105.29 O +ATOM 16269 CB ASN I 133 33.318 -53.463 18.396 1.00 94.52 C +ATOM 16270 CG ASN I 133 34.662 -53.712 19.046 1.00120.73 C +ATOM 16271 OD1 ASN I 133 35.717 -53.679 18.389 1.00 89.94 O +ATOM 16272 ND2 ASN I 133 34.633 -54.022 20.331 1.00153.13 N +ATOM 16273 N VAL I 134 32.017 -51.440 15.597 1.00109.92 N +ATOM 16274 CA VAL I 134 30.807 -51.210 14.816 1.00115.09 C +ATOM 16275 C VAL I 134 30.474 -52.497 14.048 1.00126.55 C +ATOM 16276 O VAL I 134 29.304 -52.863 13.898 1.00122.50 O +ATOM 16277 CB VAL I 134 30.997 -50.028 13.842 1.00108.03 C +ATOM 16278 CG1 VAL I 134 29.718 -49.713 13.101 1.00109.49 C +ATOM 16279 CG2 VAL I 134 31.475 -48.797 14.602 1.00116.19 C +ATOM 16280 N LYS I 135 31.515 -53.211 13.620 1.00138.32 N +ATOM 16281 CA LYS I 135 31.368 -54.605 13.197 1.00128.09 C +ATOM 16282 C LYS I 135 32.484 -55.473 13.748 1.00117.78 C +ATOM 16283 O LYS I 135 33.572 -54.983 14.109 1.00109.33 O +ATOM 16284 CB LYS I 135 31.370 -54.709 11.677 1.00127.51 C +ATOM 16285 CG LYS I 135 30.211 -53.982 11.019 1.00125.14 C +ATOM 16286 CD LYS I 135 30.346 -54.034 9.510 1.00119.00 C +ATOM 16287 CE LYS I 135 29.215 -53.313 8.818 1.00120.42 C +ATOM 16288 NZ LYS I 135 29.086 -53.779 7.413 1.00102.01 N +ATOM 16289 N SER I 136 32.218 -56.772 13.788 1.00117.02 N +ATOM 16290 CA SER I 136 33.203 -57.733 14.264 1.00124.73 C +ATOM 16291 C SER I 136 32.853 -59.145 13.833 1.00137.59 C +ATOM 16292 O SER I 136 31.689 -59.447 13.564 1.00183.26 O +ATOM 16293 CB SER I 136 33.339 -57.656 15.786 1.00108.11 C +ATOM 16294 OG SER I 136 33.132 -58.923 16.395 1.00113.78 O +ATOM 16295 N GLY I 137 33.864 -60.006 13.768 1.00120.74 N +ATOM 16296 CA GLY I 137 33.636 -61.399 13.411 1.00144.85 C +ATOM 16297 C GLY I 137 34.829 -62.294 13.652 1.00163.80 C +ATOM 16298 O GLY I 137 35.881 -61.840 14.095 1.00167.73 O +ATOM 16299 N GLY I 138 34.641 -63.593 13.432 1.00206.37 N +ATOM 16300 CA GLY I 138 35.706 -64.566 13.664 1.00211.07 C +ATOM 16301 C GLY I 138 35.414 -65.921 13.052 1.00201.84 C +ATOM 16302 O GLY I 138 34.260 -66.360 13.016 1.00226.26 O +ATOM 16303 N VAL I 139 36.470 -66.585 12.586 1.00160.66 N +ATOM 16304 CA VAL I 139 36.363 -67.933 12.047 1.00143.67 C +ATOM 16305 C VAL I 139 37.547 -68.768 12.502 1.00146.77 C +ATOM 16306 O VAL I 139 38.706 -68.386 12.297 1.00174.07 O +ATOM 16307 CB VAL I 139 36.334 -67.933 10.513 1.00135.43 C +ATOM 16308 CG1 VAL I 139 36.350 -69.357 9.993 1.00125.10 C +ATOM 16309 CG2 VAL I 139 35.107 -67.190 9.996 1.00161.73 C +ATOM 16310 N GLY I 140 37.253 -69.917 13.105 1.00155.12 N +ATOM 16311 CA GLY I 140 38.295 -70.794 13.634 1.00165.99 C +ATOM 16312 C GLY I 140 37.927 -72.267 13.637 1.00157.98 C +ATOM 16313 O GLY I 140 36.777 -72.636 13.871 1.00165.77 O +ATOM 16314 N ALA I 141 38.921 -73.112 13.396 1.00158.55 N +ATOM 16315 CA ALA I 141 38.720 -74.553 13.403 1.00164.73 C +ATOM 16316 C ALA I 141 39.939 -75.295 13.945 1.00187.05 C +ATOM 16317 O ALA I 141 41.087 -74.916 13.698 1.00200.29 O +ATOM 16318 CB ALA I 141 38.381 -75.041 12.006 1.00149.50 C +ATOM 16319 N ARG I 142 39.678 -76.338 14.716 1.00203.58 N +ATOM 16320 CA ARG I 142 40.733 -77.240 15.127 1.00207.87 C +ATOM 16321 C ARG I 142 40.317 -78.660 14.796 1.00202.61 C +ATOM 16322 O ARG I 142 39.136 -79.001 14.879 1.00164.31 O +ATOM 16323 CB ARG I 142 41.052 -77.093 16.621 1.00219.31 C +ATOM 16324 CG ARG I 142 42.224 -77.961 17.072 1.00213.21 C +ATOM 16325 CD ARG I 142 43.145 -77.237 18.028 1.00199.51 C +ATOM 16326 NE ARG I 142 42.545 -77.225 19.358 1.00195.44 N +ATOM 16327 CZ ARG I 142 42.769 -76.292 20.277 1.00179.98 C +ATOM 16328 NH1 ARG I 142 43.661 -75.327 20.065 1.00181.22 N +ATOM 16329 NH2 ARG I 142 42.137 -76.354 21.442 1.00156.22 N +ATOM 16330 N TYR I 143 41.296 -79.473 14.405 1.00218.56 N +ATOM 16331 CA TYR I 143 41.039 -80.824 13.911 1.00199.61 C +ATOM 16332 C TYR I 143 41.949 -81.859 14.582 1.00183.50 C +ATOM 16333 O TYR I 143 43.018 -82.210 14.065 1.00162.20 O +ATOM 16334 CB TYR I 143 41.228 -80.848 12.395 1.00200.65 C +ATOM 16335 CG TYR I 143 40.824 -82.135 11.746 1.00206.87 C +ATOM 16336 CD1 TYR I 143 39.478 -82.483 11.626 1.00189.20 C +ATOM 16337 CD2 TYR I 143 41.777 -82.987 11.220 1.00214.23 C +ATOM 16338 CE1 TYR I 143 39.082 -83.655 11.016 1.00158.36 C +ATOM 16339 CE2 TYR I 143 41.390 -84.162 10.599 1.00211.30 C +ATOM 16340 CZ TYR I 143 40.044 -84.491 10.504 1.00179.51 C +ATOM 16341 OH TYR I 143 39.667 -85.660 9.892 1.00169.96 O +ATOM 16342 N GLY I 145 44.192 -82.136 16.147 1.00119.90 N +ATOM 16343 CA GLY I 145 45.482 -81.661 16.619 1.00126.61 C +ATOM 16344 C GLY I 145 45.915 -80.297 16.092 1.00137.89 C +ATOM 16345 O GLY I 145 46.721 -79.619 16.739 1.00153.59 O +ATOM 16346 N ILE I 146 45.446 -79.921 14.904 1.00146.63 N +ATOM 16347 CA ILE I 146 45.941 -78.726 14.205 1.00157.51 C +ATOM 16348 C ILE I 146 44.808 -77.702 14.152 1.00193.37 C +ATOM 16349 O ILE I 146 43.662 -78.060 13.885 1.00247.98 O +ATOM 16350 CB ILE I 146 46.427 -79.047 12.761 1.00129.07 C +ATOM 16351 CG1 ILE I 146 47.186 -80.381 12.728 1.00110.96 C +ATOM 16352 CG2 ILE I 146 47.306 -77.924 12.217 1.00 97.26 C +ATOM 16353 CD1 ILE I 146 46.336 -81.566 12.316 1.00101.81 C +ATOM 16354 N GLY I 147 45.111 -76.432 14.404 1.00185.33 N +ATOM 16355 CA GLY I 147 44.062 -75.414 14.435 1.00169.54 C +ATOM 16356 C GLY I 147 44.480 -74.020 14.018 1.00167.62 C +ATOM 16357 O GLY I 147 45.642 -73.645 14.124 1.00180.52 O +ATOM 16358 N ALA I 148 43.509 -73.244 13.555 1.00166.07 N +ATOM 16359 CA ALA I 148 43.730 -71.840 13.256 1.00144.56 C +ATOM 16360 C ALA I 148 42.456 -71.033 13.516 1.00138.53 C +ATOM 16361 O ALA I 148 41.374 -71.593 13.714 1.00138.62 O +ATOM 16362 CB ALA I 148 44.211 -71.669 11.818 1.00112.43 C +ATOM 16363 N ASP I 149 42.608 -69.714 13.541 1.00142.02 N +ATOM 16364 CA ASP I 149 41.495 -68.803 13.761 1.00156.91 C +ATOM 16365 C ASP I 149 41.866 -67.398 13.350 1.00161.17 C +ATOM 16366 O ASP I 149 43.006 -66.997 13.528 1.00128.19 O +ATOM 16367 CB ASP I 149 41.154 -68.841 15.269 1.00145.31 C +ATOM 16368 CG ASP I 149 40.233 -67.714 15.748 1.00154.53 C +ATOM 16369 OD1 ASP I 149 40.742 -66.584 15.920 1.00154.22 O +ATOM 16370 OD2 ASP I 149 39.071 -68.004 16.161 1.00159.29 O +ATOM 16371 N THR I 150 40.927 -66.669 12.750 1.00165.25 N +ATOM 16372 CA THR I 150 41.071 -65.220 12.673 1.00145.30 C +ATOM 16373 C THR I 150 39.898 -64.574 13.394 1.00150.84 C +ATOM 16374 O THR I 150 38.818 -65.160 13.487 1.00137.13 O +ATOM 16375 CB THR I 150 41.170 -64.688 11.224 1.00117.71 C +ATOM 16376 OG1 THR I 150 40.001 -65.077 10.495 1.00161.77 O +ATOM 16377 CG2 THR I 150 42.406 -65.226 10.531 1.00110.31 C +ATOM 16378 N GLN I 151 40.133 -63.382 13.923 1.00144.93 N +ATOM 16379 CA GLN I 151 39.045 -62.554 14.444 1.00130.93 C +ATOM 16380 C GLN I 151 39.297 -61.091 14.018 1.00146.44 C +ATOM 16381 O GLN I 151 40.438 -60.675 13.789 1.00182.32 O +ATOM 16382 CB GLN I 151 38.823 -62.742 15.960 1.00101.86 C +ATOM 16383 CG GLN I 151 39.922 -62.164 16.815 1.00125.15 C +ATOM 16384 CD GLN I 151 39.513 -61.973 18.265 1.00143.12 C +ATOM 16385 OE1 GLN I 151 38.762 -62.776 18.813 1.00152.91 O +ATOM 16386 NE2 GLN I 151 39.960 -60.869 18.879 1.00156.15 N +ATOM 16387 N TYR I 152 38.228 -60.371 13.714 1.00139.12 N +ATOM 16388 CA TYR I 152 38.375 -58.999 13.254 1.00117.45 C +ATOM 16389 C TYR I 152 37.380 -58.108 13.936 1.00117.46 C +ATOM 16390 O TYR I 152 36.253 -58.531 14.233 1.00113.84 O +ATOM 16391 CB TYR I 152 38.266 -58.903 11.728 1.00110.82 C +ATOM 16392 CG TYR I 152 36.965 -58.369 11.175 1.00106.60 C +ATOM 16393 CD1 TYR I 152 35.751 -59.070 11.325 1.00 98.94 C +ATOM 16394 CD2 TYR I 152 36.961 -57.227 10.395 1.00 95.09 C +ATOM 16395 CE1 TYR I 152 34.563 -58.593 10.772 1.00 88.40 C +ATOM 16396 CE2 TYR I 152 35.786 -56.768 9.796 1.00108.91 C +ATOM 16397 CZ TYR I 152 34.591 -57.458 9.979 1.00 96.96 C +ATOM 16398 OH TYR I 152 33.446 -56.979 9.393 1.00 74.11 O +ATOM 16399 N GLN I 153 37.796 -56.872 14.196 1.00110.24 N +ATOM 16400 CA GLN I 153 36.861 -55.840 14.628 1.00116.78 C +ATOM 16401 C GLN I 153 37.103 -54.531 13.870 1.00107.91 C +ATOM 16402 O GLN I 153 38.197 -54.309 13.339 1.00107.35 O +ATOM 16403 CB GLN I 153 37.014 -55.609 16.120 1.00117.93 C +ATOM 16404 CG GLN I 153 36.635 -56.801 17.003 1.00129.65 C +ATOM 16405 CD GLN I 153 36.960 -56.535 18.481 1.00147.97 C +ATOM 16406 OE1 GLN I 153 37.756 -55.646 18.809 1.00153.05 O +ATOM 16407 NE2 GLN I 153 36.317 -57.278 19.375 1.00163.73 N +ATOM 16408 N LEU I 154 36.055 -53.718 13.727 1.00 90.30 N +ATOM 16409 CA LEU I 154 36.235 -52.405 13.117 1.00 84.31 C +ATOM 16410 C LEU I 154 35.386 -51.331 13.766 1.00 89.86 C +ATOM 16411 O LEU I 154 34.228 -51.565 14.153 1.00 86.67 O +ATOM 16412 CB LEU I 154 35.988 -52.445 11.612 1.00 77.36 C +ATOM 16413 CG LEU I 154 34.540 -52.630 11.187 1.00 97.80 C +ATOM 16414 CD1 LEU I 154 33.878 -51.295 10.892 1.00111.82 C +ATOM 16415 CD2 LEU I 154 34.471 -53.544 9.973 1.00123.79 C +ATOM 16416 N ASP I 155 35.965 -50.130 13.784 1.00109.64 N +ATOM 16417 CA ASP I 155 35.463 -48.966 14.525 1.00 98.25 C +ATOM 16418 C ASP I 155 35.245 -47.809 13.536 1.00101.00 C +ATOM 16419 O ASP I 155 35.737 -47.846 12.408 1.00 77.20 O +ATOM 16420 CB ASP I 155 36.483 -48.517 15.570 1.00 98.71 C +ATOM 16421 CG ASP I 155 37.036 -49.675 16.380 1.00134.05 C +ATOM 16422 OD1 ASP I 155 37.924 -50.397 15.866 1.00187.06 O +ATOM 16423 OD2 ASP I 155 36.563 -49.887 17.508 1.00126.35 O +ATOM 16424 N GLN I 156 34.454 -46.816 13.935 1.00 97.00 N +ATOM 16425 CA GLN I 156 34.136 -45.706 13.034 1.00 78.95 C +ATOM 16426 C GLN I 156 34.665 -44.406 13.600 1.00 61.02 C +ATOM 16427 O GLN I 156 34.816 -44.269 14.823 1.00 52.22 O +ATOM 16428 CB GLN I 156 32.617 -45.625 12.794 1.00 96.91 C +ATOM 16429 CG GLN I 156 32.225 -44.683 11.670 1.00101.91 C +ATOM 16430 CD GLN I 156 30.881 -45.023 11.054 1.00 90.70 C +ATOM 16431 OE1 GLN I 156 30.097 -45.803 11.620 1.00 88.87 O +ATOM 16432 NE2 GLN I 156 30.558 -44.353 9.942 1.00 70.97 N +ATOM 16433 N ILE I 157 34.934 -43.458 12.719 1.00 45.90 N +ATOM 16434 CA ILE I 157 35.300 -42.133 13.142 1.00 63.14 C +ATOM 16435 C ILE I 157 34.803 -41.126 12.113 1.00 71.43 C +ATOM 16436 O ILE I 157 34.810 -41.385 10.916 1.00 56.68 O +ATOM 16437 CB ILE I 157 36.830 -42.037 13.294 1.00 84.87 C +ATOM 16438 CG1 ILE I 157 37.222 -40.908 14.266 1.00117.20 C +ATOM 16439 CG2 ILE I 157 37.497 -41.825 11.952 1.00 76.39 C +ATOM 16440 CD1 ILE I 157 38.700 -40.886 14.626 1.00128.57 C +ATOM 16441 N ALA I 158 34.290 -39.989 12.574 1.00 87.06 N +ATOM 16442 CA ALA I 158 33.720 -39.015 11.639 1.00 77.79 C +ATOM 16443 C ALA I 158 34.207 -37.636 11.978 1.00 61.13 C +ATOM 16444 O ALA I 158 34.516 -37.348 13.150 1.00 78.29 O +ATOM 16445 CB ALA I 158 32.197 -39.079 11.642 1.00 77.06 C +ATOM 16446 N VAL I 159 34.268 -36.795 10.961 1.00 42.63 N +ATOM 16447 CA VAL I 159 34.828 -35.489 11.115 1.00 48.17 C +ATOM 16448 C VAL I 159 34.034 -34.461 10.366 1.00 60.95 C +ATOM 16449 O VAL I 159 33.685 -34.647 9.203 1.00 74.29 O +ATOM 16450 CB VAL I 159 36.276 -35.443 10.624 1.00 52.61 C +ATOM 16451 CG1 VAL I 159 36.716 -34.022 10.315 1.00 54.31 C +ATOM 16452 CG2 VAL I 159 37.200 -36.044 11.689 1.00 70.23 C +ATOM 16453 N ASN I 160 33.677 -33.390 11.077 1.00 79.11 N +ATOM 16454 CA ASN I 160 33.033 -32.236 10.461 1.00 83.79 C +ATOM 16455 C ASN I 160 34.117 -31.204 10.212 1.00 67.63 C +ATOM 16456 O ASN I 160 34.902 -30.900 11.115 1.00 46.19 O +ATOM 16457 CB ASN I 160 31.938 -31.678 11.390 1.00 89.46 C +ATOM 16458 CG ASN I 160 31.279 -30.405 10.852 1.00106.03 C +ATOM 16459 OD1 ASN I 160 31.947 -29.461 10.443 1.00115.83 O +ATOM 16460 ND2 ASN I 160 29.958 -30.352 10.925 1.00122.70 N +ATOM 16461 N LEU I 161 34.167 -30.700 8.980 1.00 49.78 N +ATOM 16462 CA LEU I 161 34.848 -29.454 8.710 1.00 52.76 C +ATOM 16463 C LEU I 161 33.901 -28.466 8.057 1.00 46.26 C +ATOM 16464 O LEU I 161 33.018 -28.830 7.322 1.00 42.41 O +ATOM 16465 CB LEU I 161 36.038 -29.695 7.799 1.00 61.84 C +ATOM 16466 CG LEU I 161 37.146 -30.565 8.370 1.00 66.55 C +ATOM 16467 CD1 LEU I 161 38.155 -30.882 7.280 1.00 75.03 C +ATOM 16468 CD2 LEU I 161 37.807 -29.851 9.543 1.00 60.93 C +ATOM 16469 N ARG I 162 34.093 -27.193 8.319 1.00 60.47 N +ATOM 16470 CA ARG I 162 33.208 -26.200 7.748 1.00 74.44 C +ATOM 16471 C ARG I 162 33.849 -24.815 7.588 1.00 74.50 C +ATOM 16472 O ARG I 162 34.470 -24.276 8.506 1.00 70.28 O +ATOM 16473 CB ARG I 162 31.892 -26.121 8.540 1.00 92.42 C +ATOM 16474 CG ARG I 162 31.981 -25.657 9.989 1.00118.46 C +ATOM 16475 CD ARG I 162 30.600 -25.240 10.491 1.00124.69 C +ATOM 16476 NE ARG I 162 30.624 -24.612 11.813 1.00128.52 N +ATOM 16477 CZ ARG I 162 30.696 -25.275 12.972 1.00126.87 C +ATOM 16478 NH1 ARG I 162 30.815 -26.603 13.006 1.00 82.38 N +ATOM 16479 NH2 ARG I 162 30.693 -24.588 14.110 1.00154.29 N +ATOM 16480 N VAL I 163 33.682 -24.268 6.390 1.00 85.56 N +ATOM 16481 CA VAL I 163 34.178 -22.934 6.042 1.00 96.75 C +ATOM 16482 C VAL I 163 33.191 -21.864 6.451 1.00 88.27 C +ATOM 16483 O VAL I 163 32.045 -21.873 6.003 1.00121.16 O +ATOM 16484 CB VAL I 163 34.358 -22.764 4.522 1.00112.13 C +ATOM 16485 CG1 VAL I 163 34.857 -21.345 4.207 1.00 95.12 C +ATOM 16486 CG2 VAL I 163 35.281 -23.854 3.971 1.00130.80 C +ATOM 16487 N VAL I 164 33.667 -20.933 7.264 1.00 72.76 N +ATOM 16488 CA VAL I 164 32.859 -19.831 7.741 1.00 47.69 C +ATOM 16489 C VAL I 164 33.391 -18.583 7.180 1.00 38.03 C +ATOM 16490 O VAL I 164 34.619 -18.357 7.174 1.00 54.26 O +ATOM 16491 CB VAL I 164 32.943 -19.723 9.255 1.00 44.28 C +ATOM 16492 CG1 VAL I 164 32.148 -18.535 9.723 1.00 40.70 C +ATOM 16493 CG2 VAL I 164 32.426 -21.004 9.906 1.00 50.19 C +ATOM 16494 N ASN I 165 32.498 -17.769 6.698 1.00 39.97 N +ATOM 16495 CA ASN I 165 32.902 -16.479 6.168 1.00 73.83 C +ATOM 16496 C ASN I 165 33.059 -15.430 7.270 1.00 71.61 C +ATOM 16497 O ASN I 165 32.085 -15.089 7.933 1.00 94.01 O +ATOM 16498 CB ASN I 165 31.894 -15.963 5.136 1.00102.07 C +ATOM 16499 CG ASN I 165 32.355 -14.690 4.468 1.00100.55 C +ATOM 16500 OD1 ASN I 165 33.562 -14.371 4.475 1.00157.59 O +ATOM 16501 ND2 ASN I 165 31.444 -14.040 3.772 1.00 99.75 N +ATOM 16502 N VAL I 166 34.269 -14.885 7.408 1.00 72.87 N +ATOM 16503 CA VAL I 166 34.589 -13.934 8.454 1.00 60.59 C +ATOM 16504 C VAL I 166 33.750 -12.700 8.272 1.00 65.60 C +ATOM 16505 O VAL I 166 33.257 -12.148 9.268 1.00121.10 O +ATOM 16506 CB VAL I 166 36.070 -13.550 8.422 1.00 61.69 C +ATOM 16507 CG1 VAL I 166 36.310 -12.169 9.028 1.00 74.02 C +ATOM 16508 CG2 VAL I 166 36.919 -14.629 9.102 1.00 49.24 C +ATOM 16509 N SER I 167 33.529 -12.298 7.020 1.00 58.04 N +ATOM 16510 CA SER I 167 32.866 -11.041 6.741 1.00 65.84 C +ATOM 16511 C SER I 167 31.355 -11.060 7.024 1.00 87.77 C +ATOM 16512 O SER I 167 30.729 -9.990 7.147 1.00100.99 O +ATOM 16513 CB SER I 167 33.091 -10.672 5.296 1.00 72.14 C +ATOM 16514 OG SER I 167 34.447 -10.850 4.944 1.00 72.54 O +ATOM 16515 N THR I 168 30.771 -12.253 7.201 1.00 96.29 N +ATOM 16516 CA THR I 168 29.319 -12.366 7.517 1.00 75.38 C +ATOM 16517 C THR I 168 28.913 -13.358 8.639 1.00 61.88 C +ATOM 16518 O THR I 168 27.955 -13.153 9.401 1.00 43.15 O +ATOM 16519 CB THR I 168 28.581 -12.814 6.276 1.00 77.28 C +ATOM 16520 OG1 THR I 168 29.220 -13.979 5.775 1.00 45.57 O +ATOM 16521 CG2 THR I 168 28.590 -11.698 5.247 1.00 97.36 C +ATOM 16522 N GLY I 169 29.685 -14.415 8.786 1.00 59.83 N +ATOM 16523 CA GLY I 169 29.338 -15.440 9.744 1.00 55.67 C +ATOM 16524 C GLY I 169 28.588 -16.537 9.026 1.00 53.88 C +ATOM 16525 O GLY I 169 28.329 -17.587 9.632 1.00 52.57 O +ATOM 16526 N GLU I 170 28.189 -16.288 7.760 1.00 42.53 N +ATOM 16527 CA GLU I 170 27.583 -17.339 6.939 1.00 40.16 C +ATOM 16528 C GLU I 170 28.575 -18.466 6.971 1.00 34.53 C +ATOM 16529 O GLU I 170 29.725 -18.274 6.640 1.00 43.46 O +ATOM 16530 CB GLU I 170 27.309 -16.856 5.518 1.00 45.63 C +ATOM 16531 CG GLU I 170 26.065 -15.989 5.390 1.00 84.32 C +ATOM 16532 CD GLU I 170 26.180 -14.826 4.395 1.00115.27 C +ATOM 16533 OE1 GLU I 170 27.289 -14.547 3.923 1.00 84.20 O +ATOM 16534 OE2 GLU I 170 25.144 -14.174 4.086 1.00162.60 O +ATOM 16535 N ILE I 171 28.143 -19.648 7.355 1.00 35.65 N +ATOM 16536 CA ILE I 171 28.848 -20.828 6.941 1.00 47.37 C +ATOM 16537 C ILE I 171 28.799 -21.024 5.398 1.00 70.04 C +ATOM 16538 O ILE I 171 27.720 -21.052 4.800 1.00 59.96 O +ATOM 16539 CB ILE I 171 28.288 -22.080 7.622 1.00 37.73 C +ATOM 16540 CG1 ILE I 171 28.583 -21.974 9.106 1.00 30.97 C +ATOM 16541 CG2 ILE I 171 28.905 -23.341 6.992 1.00 33.02 C +ATOM 16542 CD1 ILE I 171 27.781 -22.941 9.928 1.00 26.30 C +ATOM 16543 N LEU I 172 29.973 -21.101 4.746 1.00 80.34 N +ATOM 16544 CA LEU I 172 30.031 -21.186 3.281 1.00 76.14 C +ATOM 16545 C LEU I 172 30.079 -22.646 2.784 1.00 87.73 C +ATOM 16546 O LEU I 172 29.890 -22.944 1.569 1.00 70.23 O +ATOM 16547 CB LEU I 172 31.212 -20.397 2.721 1.00 79.74 C +ATOM 16548 CG LEU I 172 31.093 -18.852 2.843 1.00 95.73 C +ATOM 16549 CD1 LEU I 172 32.171 -17.996 2.160 1.00 98.05 C +ATOM 16550 CD2 LEU I 172 29.707 -18.360 2.450 1.00108.85 C +ATOM 16551 N SER I 173 30.322 -23.561 3.730 1.00 68.72 N +ATOM 16552 CA SER I 173 30.408 -24.979 3.415 1.00 59.03 C +ATOM 16553 C SER I 173 30.510 -25.807 4.675 1.00 58.50 C +ATOM 16554 O SER I 173 31.349 -25.563 5.515 1.00 81.64 O +ATOM 16555 CB SER I 173 31.637 -25.261 2.525 1.00 60.09 C +ATOM 16556 OG SER I 173 31.906 -26.648 2.477 1.00 69.94 O +ATOM 16557 N SER I 174 29.718 -26.858 4.752 1.00 77.60 N +ATOM 16558 CA SER I 174 29.893 -27.881 5.785 1.00 73.89 C +ATOM 16559 C SER I 174 30.056 -29.218 5.098 1.00 88.57 C +ATOM 16560 O SER I 174 29.321 -29.550 4.156 1.00105.94 O +ATOM 16561 CB SER I 174 28.674 -27.937 6.740 1.00 81.11 C +ATOM 16562 OG SER I 174 28.900 -28.749 7.879 1.00 42.69 O +ATOM 16563 N VAL I 175 30.994 -30.011 5.603 1.00100.38 N +ATOM 16564 CA VAL I 175 31.221 -31.372 5.092 1.00 86.58 C +ATOM 16565 C VAL I 175 31.409 -32.385 6.214 1.00 61.46 C +ATOM 16566 O VAL I 175 32.022 -32.070 7.250 1.00 57.02 O +ATOM 16567 CB VAL I 175 32.442 -31.406 4.155 1.00105.07 C +ATOM 16568 CG1 VAL I 175 32.200 -30.530 2.936 1.00132.87 C +ATOM 16569 CG2 VAL I 175 33.697 -30.932 4.864 1.00117.00 C +ATOM 16570 N ASN I 176 30.909 -33.590 5.987 1.00 56.04 N +ATOM 16571 CA ASN I 176 30.920 -34.644 7.003 1.00 74.36 C +ATOM 16572 C ASN I 176 31.583 -35.951 6.554 1.00 75.51 C +ATOM 16573 O ASN I 176 30.923 -36.775 5.951 1.00 88.51 O +ATOM 16574 CB ASN I 176 29.474 -34.914 7.423 1.00 81.78 C +ATOM 16575 CG ASN I 176 29.108 -34.181 8.728 1.00 96.34 C +ATOM 16576 OD1 ASN I 176 29.800 -33.224 9.071 1.00 61.32 O +ATOM 16577 ND2 ASN I 176 27.980 -34.551 9.400 1.00 99.11 N +ATOM 16578 N THR I 177 32.874 -36.137 6.858 1.00 61.44 N +ATOM 16579 CA THR I 177 33.622 -37.298 6.368 1.00 50.30 C +ATOM 16580 C THR I 177 33.704 -38.365 7.446 1.00 55.89 C +ATOM 16581 O THR I 177 33.476 -38.095 8.627 1.00 45.75 O +ATOM 16582 CB THR I 177 35.050 -36.933 5.936 1.00 49.79 C +ATOM 16583 OG1 THR I 177 35.838 -36.581 7.079 1.00 54.48 O +ATOM 16584 CG2 THR I 177 35.067 -35.769 4.954 1.00 48.66 C +ATOM 16585 N SER I 178 33.980 -39.590 7.022 1.00 66.13 N +ATOM 16586 CA SER I 178 33.963 -40.743 7.921 1.00 68.58 C +ATOM 16587 C SER I 178 34.992 -41.745 7.489 1.00 76.26 C +ATOM 16588 O SER I 178 35.307 -41.880 6.295 1.00106.02 O +ATOM 16589 CB SER I 178 32.574 -41.412 7.952 1.00 67.08 C +ATOM 16590 OG SER I 178 32.619 -42.701 8.560 1.00 42.73 O +ATOM 16591 N LYS I 179 35.464 -42.521 8.446 1.00 73.93 N +ATOM 16592 CA LYS I 179 36.514 -43.481 8.153 1.00 92.88 C +ATOM 16593 C LYS I 179 36.504 -44.654 9.147 1.00 88.00 C +ATOM 16594 O LYS I 179 36.123 -44.500 10.315 1.00 65.63 O +ATOM 16595 CB LYS I 179 37.842 -42.755 8.198 1.00102.48 C +ATOM 16596 CG LYS I 179 38.861 -43.236 7.189 1.00117.32 C +ATOM 16597 CD LYS I 179 39.768 -44.284 7.816 1.00145.52 C +ATOM 16598 CE LYS I 179 40.688 -44.883 6.775 1.00159.20 C +ATOM 16599 NZ LYS I 179 41.357 -46.100 7.284 1.00149.86 N +ATOM 16600 N THR I 180 36.865 -45.832 8.650 1.00 67.94 N +ATOM 16601 CA THR I 180 36.739 -47.035 9.434 1.00 77.04 C +ATOM 16602 C THR I 180 38.128 -47.511 9.847 1.00104.75 C +ATOM 16603 O THR I 180 39.058 -47.582 9.030 1.00 83.08 O +ATOM 16604 CB THR I 180 35.968 -48.149 8.695 1.00 77.59 C +ATOM 16605 OG1 THR I 180 36.362 -49.435 9.193 1.00 66.92 O +ATOM 16606 CG2 THR I 180 36.225 -48.089 7.198 1.00 83.25 C +ATOM 16607 N ILE I 181 38.254 -47.860 11.129 1.00133.50 N +ATOM 16608 CA ILE I 181 39.518 -48.371 11.682 1.00115.21 C +ATOM 16609 C ILE I 181 39.489 -49.902 11.812 1.00120.64 C +ATOM 16610 O ILE I 181 38.656 -50.456 12.532 1.00140.82 O +ATOM 16611 CB ILE I 181 39.821 -47.744 13.064 1.00105.71 C +ATOM 16612 CG1 ILE I 181 39.754 -46.218 12.988 1.00102.73 C +ATOM 16613 CG2 ILE I 181 41.198 -48.152 13.565 1.00136.95 C +ATOM 16614 CD1 ILE I 181 38.706 -45.613 13.896 1.00100.95 C +ATOM 16615 N LEU I 182 40.376 -50.569 11.071 1.00106.69 N +ATOM 16616 CA LEU I 182 40.405 -52.026 11.001 1.00 99.05 C +ATOM 16617 C LEU I 182 41.347 -52.649 12.023 1.00104.54 C +ATOM 16618 O LEU I 182 42.484 -52.193 12.200 1.00101.80 O +ATOM 16619 CB LEU I 182 40.811 -52.467 9.594 1.00 97.80 C +ATOM 16620 CG LEU I 182 40.921 -53.979 9.384 1.00 98.16 C +ATOM 16621 CD1 LEU I 182 39.592 -54.716 9.610 1.00 96.12 C +ATOM 16622 CD2 LEU I 182 41.461 -54.222 7.986 1.00 84.35 C +ATOM 16623 N SER I 183 40.894 -53.747 12.626 1.00110.64 N +ATOM 16624 CA SER I 183 41.732 -54.560 13.495 1.00132.23 C +ATOM 16625 C SER I 183 41.500 -56.050 13.237 1.00134.15 C +ATOM 16626 O SER I 183 40.376 -56.478 13.002 1.00120.70 O +ATOM 16627 CB SER I 183 41.429 -54.236 14.954 1.00129.50 C +ATOM 16628 OG SER I 183 41.184 -52.847 15.118 1.00147.19 O +ATOM 16629 N TYR I 184 42.577 -56.835 13.251 1.00146.99 N +ATOM 16630 CA TYR I 184 42.459 -58.285 13.100 1.00134.83 C +ATOM 16631 C TYR I 184 43.557 -59.097 13.784 1.00124.78 C +ATOM 16632 O TYR I 184 44.668 -58.617 14.039 1.00128.01 O +ATOM 16633 CB TYR I 184 42.387 -58.674 11.627 1.00120.44 C +ATOM 16634 CG TYR I 184 43.595 -58.232 10.823 1.00 97.55 C +ATOM 16635 CD1 TYR I 184 44.728 -59.029 10.731 1.00 69.87 C +ATOM 16636 CD2 TYR I 184 43.582 -57.023 10.136 1.00 97.79 C +ATOM 16637 CE1 TYR I 184 45.808 -58.640 9.966 1.00 63.38 C +ATOM 16638 CE2 TYR I 184 44.653 -56.634 9.349 1.00 90.48 C +ATOM 16639 CZ TYR I 184 45.760 -57.454 9.258 1.00 71.92 C +ATOM 16640 OH TYR I 184 46.836 -57.027 8.518 1.00 53.81 O +ATOM 16641 N GLU I 185 43.203 -60.343 14.076 1.00119.56 N +ATOM 16642 CA GLU I 185 44.024 -61.246 14.835 1.00137.44 C +ATOM 16643 C GLU I 185 44.032 -62.626 14.203 1.00159.85 C +ATOM 16644 O GLU I 185 43.033 -63.328 14.205 1.00174.08 O +ATOM 16645 CB GLU I 185 43.502 -61.274 16.268 1.00136.49 C +ATOM 16646 CG GLU I 185 44.092 -62.316 17.198 1.00149.06 C +ATOM 16647 CD GLU I 185 43.649 -62.084 18.636 1.00156.91 C +ATOM 16648 OE1 GLU I 185 42.967 -61.073 18.901 1.00169.93 O +ATOM 16649 OE2 GLU I 185 44.043 -62.876 19.511 1.00166.61 O +ATOM 16650 N VAL I 186 45.171 -62.985 13.621 1.00174.51 N +ATOM 16651 CA VAL I 186 45.357 -64.284 12.995 1.00154.31 C +ATOM 16652 C VAL I 186 46.169 -65.178 13.917 1.00173.52 C +ATOM 16653 O VAL I 186 47.124 -64.743 14.568 1.00186.47 O +ATOM 16654 CB VAL I 186 46.086 -64.160 11.647 1.00126.49 C +ATOM 16655 CG1 VAL I 186 46.097 -65.497 10.928 1.00117.23 C +ATOM 16656 CG2 VAL I 186 45.429 -63.092 10.789 1.00116.00 C +ATOM 16657 N GLN I 187 45.772 -66.435 14.001 1.00170.55 N +ATOM 16658 CA GLN I 187 46.407 -67.313 14.937 1.00176.92 C +ATOM 16659 C GLN I 187 46.344 -68.777 14.453 1.00206.06 C +ATOM 16660 O GLN I 187 45.337 -69.234 13.903 1.00245.11 O +ATOM 16661 CB GLN I 187 45.816 -67.075 16.317 1.00143.97 C +ATOM 16662 CG GLN I 187 46.349 -68.026 17.346 1.00146.74 C +ATOM 16663 CD GLN I 187 45.645 -67.877 18.665 1.00139.53 C +ATOM 16664 OE1 GLN I 187 44.478 -67.517 18.703 1.00116.57 O +ATOM 16665 NE2 GLN I 187 46.379 -68.068 19.759 1.00156.26 N +ATOM 16666 N ALA I 188 47.473 -69.475 14.556 1.00216.38 N +ATOM 16667 CA ALA I 188 47.547 -70.875 14.147 1.00188.16 C +ATOM 16668 C ALA I 188 48.401 -71.664 15.137 1.00180.66 C +ATOM 16669 O ALA I 188 49.422 -71.180 15.609 1.00175.60 O +ATOM 16670 CB ALA I 188 48.097 -70.998 12.732 1.00160.60 C +ATOM 16671 N GLY I 189 47.971 -72.874 15.462 1.00170.78 N +ATOM 16672 CA GLY I 189 48.704 -73.722 16.385 1.00181.85 C +ATOM 16673 C GLY I 189 48.651 -75.187 16.002 1.00207.24 C +ATOM 16674 O GLY I 189 47.604 -75.698 15.605 1.00254.88 O +ATOM 16675 N VAL I 190 49.789 -75.863 16.117 1.00197.86 N +ATOM 16676 CA VAL I 190 49.864 -77.291 15.862 1.00166.74 C +ATOM 16677 C VAL I 190 50.177 -78.023 17.178 1.00159.00 C +ATOM 16678 O VAL I 190 51.051 -77.608 17.950 1.00206.41 O +ATOM 16679 CB VAL I 190 50.929 -77.608 14.788 1.00137.17 C +ATOM 16680 CG1 VAL I 190 50.817 -79.064 14.360 1.00133.28 C +ATOM 16681 CG2 VAL I 190 50.799 -76.663 13.597 1.00101.43 C +ATOM 16682 N PHE I 191 49.477 -79.124 17.428 1.00130.06 N +ATOM 16683 CA PHE I 191 49.563 -79.813 18.720 1.00145.88 C +ATOM 16684 C PHE I 191 49.717 -81.323 18.501 1.00150.28 C +ATOM 16685 O PHE I 191 48.941 -81.917 17.736 1.00185.47 O +ATOM 16686 CB PHE I 191 48.305 -79.502 19.555 1.00148.94 C +ATOM 16687 CG PHE I 191 48.483 -79.711 21.031 1.00146.12 C +ATOM 16688 CD1 PHE I 191 48.570 -80.991 21.558 1.00155.84 C +ATOM 16689 CD2 PHE I 191 48.548 -78.628 21.896 1.00148.45 C +ATOM 16690 CE1 PHE I 191 48.724 -81.188 22.920 1.00148.39 C +ATOM 16691 CE2 PHE I 191 48.717 -78.817 23.258 1.00143.00 C +ATOM 16692 CZ PHE I 191 48.797 -80.100 23.772 1.00134.29 C +ATOM 16693 N LEU I 200 54.771 -82.350 21.121 1.00133.61 N +ATOM 16694 CA LEU I 200 54.925 -81.256 20.169 1.00165.32 C +ATOM 16695 C LEU I 200 53.765 -80.268 20.266 1.00216.36 C +ATOM 16696 O LEU I 200 52.628 -80.588 19.886 1.00267.43 O +ATOM 16697 CB LEU I 200 55.026 -81.768 18.721 1.00151.40 C +ATOM 16698 CG LEU I 200 54.997 -80.662 17.638 1.00126.91 C +ATOM 16699 CD1 LEU I 200 56.400 -80.374 17.141 1.00121.18 C +ATOM 16700 CD2 LEU I 200 54.053 -80.988 16.481 1.00125.01 C +ATOM 16701 N GLU I 201 54.073 -79.052 20.711 1.00239.00 N +ATOM 16702 CA GLU I 201 53.218 -77.896 20.457 1.00235.64 C +ATOM 16703 C GLU I 201 53.978 -76.833 19.669 1.00262.47 C +ATOM 16704 O GLU I 201 55.194 -76.689 19.812 1.00316.77 O +ATOM 16705 CB GLU I 201 52.716 -77.299 21.764 1.00190.21 C +ATOM 16706 CG GLU I 201 51.488 -76.425 21.574 1.00193.15 C +ATOM 16707 CD GLU I 201 50.978 -75.826 22.871 1.00228.04 C +ATOM 16708 OE1 GLU I 201 50.790 -76.580 23.852 1.00285.82 O +ATOM 16709 OE2 GLU I 201 50.753 -74.596 22.910 1.00245.84 O +ATOM 16710 N GLY I 202 53.262 -76.114 18.810 1.00260.15 N +ATOM 16711 CA GLY I 202 53.840 -74.988 18.081 1.00244.05 C +ATOM 16712 C GLY I 202 52.782 -73.967 17.717 1.00242.05 C +ATOM 16713 O GLY I 202 51.767 -74.307 17.110 1.00285.27 O +ATOM 16714 N GLU I 203 53.006 -72.712 18.098 1.00212.27 N +ATOM 16715 CA GLU I 203 52.012 -71.667 17.876 1.00161.97 C +ATOM 16716 C GLU I 203 52.583 -70.422 17.205 1.00135.25 C +ATOM 16717 O GLU I 203 53.661 -69.937 17.565 1.00136.15 O +ATOM 16718 CB GLU I 203 51.351 -71.285 19.193 1.00151.33 C +ATOM 16719 CG GLU I 203 50.502 -72.407 19.783 1.00167.19 C +ATOM 16720 CD GLU I 203 49.741 -72.017 21.043 1.00202.48 C +ATOM 16721 OE1 GLU I 203 49.992 -70.916 21.581 1.00258.53 O +ATOM 16722 OE2 GLU I 203 48.913 -72.833 21.520 1.00241.23 O +ATOM 16723 N VAL I 204 51.846 -69.927 16.219 1.00103.66 N +ATOM 16724 CA VAL I 204 52.113 -68.641 15.610 1.00109.70 C +ATOM 16725 C VAL I 204 50.879 -67.762 15.778 1.00135.87 C +ATOM 16726 O VAL I 204 49.746 -68.203 15.589 1.00141.72 O +ATOM 16727 CB VAL I 204 52.468 -68.783 14.115 1.00 94.65 C +ATOM 16728 CG1 VAL I 204 52.381 -67.442 13.385 1.00 86.43 C +ATOM 16729 CG2 VAL I 204 53.861 -69.378 13.978 1.00100.64 C +ATOM 16730 N GLY I 205 51.114 -66.517 16.176 1.00172.53 N +ATOM 16731 CA GLY I 205 50.049 -65.533 16.306 1.00162.82 C +ATOM 16732 C GLY I 205 50.482 -64.191 15.734 1.00149.53 C +ATOM 16733 O GLY I 205 51.665 -63.828 15.796 1.00183.22 O +ATOM 16734 N TYR I 206 49.527 -63.454 15.184 1.00112.06 N +ATOM 16735 CA TYR I 206 49.779 -62.107 14.681 1.00100.97 C +ATOM 16736 C TYR I 206 48.543 -61.244 14.833 1.00111.31 C +ATOM 16737 O TYR I 206 47.437 -61.722 14.661 1.00106.20 O +ATOM 16738 CB TYR I 206 50.170 -62.146 13.209 1.00 92.17 C +ATOM 16739 CG TYR I 206 50.378 -60.773 12.607 1.00 93.54 C +ATOM 16740 CD1 TYR I 206 51.533 -60.035 12.883 1.00117.00 C +ATOM 16741 CD2 TYR I 206 49.422 -60.207 11.788 1.00 96.54 C +ATOM 16742 CE1 TYR I 206 51.730 -58.777 12.341 1.00124.92 C +ATOM 16743 CE2 TYR I 206 49.607 -58.953 11.238 1.00107.77 C +ATOM 16744 CZ TYR I 206 50.758 -58.246 11.511 1.00130.93 C +ATOM 16745 OH TYR I 206 50.958 -57.020 10.924 1.00173.59 O +ATOM 16746 N THR I 207 48.731 -59.977 15.202 1.00136.48 N +ATOM 16747 CA THR I 207 47.609 -59.040 15.373 1.00111.13 C +ATOM 16748 C THR I 207 47.958 -57.672 14.793 1.00 95.48 C +ATOM 16749 O THR I 207 49.076 -57.170 14.972 1.00100.21 O +ATOM 16750 CB THR I 207 47.218 -58.858 16.858 1.00 97.25 C +ATOM 16751 OG1 THR I 207 48.320 -58.300 17.580 1.00104.02 O +ATOM 16752 CG2 THR I 207 46.848 -60.184 17.493 1.00 93.89 C +ATOM 16753 N SER I 208 47.009 -57.080 14.084 1.00 90.52 N +ATOM 16754 CA SER I 208 47.243 -55.772 13.478 1.00 90.48 C +ATOM 16755 C SER I 208 46.078 -54.829 13.710 1.00 99.54 C +ATOM 16756 O SER I 208 44.933 -55.147 13.388 1.00145.84 O +ATOM 16757 CB SER I 208 47.523 -55.889 11.975 1.00 89.78 C +ATOM 16758 OG SER I 208 47.605 -54.595 11.377 1.00 68.67 O +ATOM 16759 N ASN I 209 46.391 -53.657 14.255 1.00100.58 N +ATOM 16760 CA ASN I 209 45.432 -52.560 14.414 1.00 92.82 C +ATOM 16761 C ASN I 209 45.816 -51.399 13.539 1.00101.45 C +ATOM 16762 O ASN I 209 46.999 -51.031 13.452 1.00158.33 O +ATOM 16763 CB ASN I 209 45.414 -52.075 15.849 1.00 89.56 C +ATOM 16764 CG ASN I 209 44.814 -53.093 16.775 1.00 86.91 C +ATOM 16765 OD1 ASN I 209 43.605 -53.149 16.937 1.00116.86 O +ATOM 16766 ND2 ASN I 209 45.658 -53.864 17.432 1.00 88.60 N +ATOM 16767 N GLU I 210 44.828 -50.815 12.889 1.00 86.49 N +ATOM 16768 CA GLU I 210 45.060 -49.556 12.208 1.00 96.76 C +ATOM 16769 C GLU I 210 45.289 -48.495 13.267 1.00 77.61 C +ATOM 16770 O GLU I 210 44.666 -48.513 14.329 1.00 65.64 O +ATOM 16771 CB GLU I 210 43.852 -49.186 11.348 1.00125.10 C +ATOM 16772 CG GLU I 210 44.175 -48.643 9.967 1.00125.38 C +ATOM 16773 CD GLU I 210 42.972 -48.690 9.020 1.00124.96 C +ATOM 16774 OE1 GLU I 210 42.063 -49.546 9.183 1.00 73.36 O +ATOM 16775 OE2 GLU I 210 42.958 -47.862 8.084 1.00145.31 O +ATOM 16776 N PRO I 211 46.173 -47.558 12.974 1.00 78.32 N +ATOM 16777 CA PRO I 211 46.282 -46.435 13.881 1.00120.40 C +ATOM 16778 C PRO I 211 45.088 -45.473 13.744 1.00117.20 C +ATOM 16779 O PRO I 211 44.827 -44.975 12.652 1.00 52.81 O +ATOM 16780 CB PRO I 211 47.605 -45.759 13.454 1.00142.39 C +ATOM 16781 CG PRO I 211 48.333 -46.787 12.650 1.00112.74 C +ATOM 16782 CD PRO I 211 47.244 -47.561 11.974 1.00 86.00 C +ATOM 16783 N VAL I 212 44.444 -45.171 14.876 1.00133.85 N +ATOM 16784 CA VAL I 212 43.333 -44.223 14.927 1.00102.32 C +ATOM 16785 C VAL I 212 43.829 -42.834 14.569 1.00 85.45 C +ATOM 16786 O VAL I 212 43.202 -42.104 13.792 1.00 92.63 O +ATOM 16787 CB VAL I 212 42.716 -44.149 16.334 1.00 91.60 C +ATOM 16788 CG1 VAL I 212 41.475 -43.281 16.299 1.00 89.09 C +ATOM 16789 CG2 VAL I 212 42.380 -45.547 16.862 1.00103.47 C +ATOM 16790 N MET I 213 44.989 -42.511 15.118 1.00 64.25 N +ATOM 16791 CA MET I 213 45.842 -41.419 14.659 1.00 82.02 C +ATOM 16792 C MET I 213 45.845 -41.163 13.138 1.00 82.95 C +ATOM 16793 O MET I 213 45.595 -40.039 12.653 1.00 79.72 O +ATOM 16794 CB MET I 213 47.245 -41.814 15.121 1.00 99.76 C +ATOM 16795 CG MET I 213 48.363 -40.823 14.931 1.00121.95 C +ATOM 16796 SD MET I 213 49.845 -41.641 15.606 1.00140.83 S +ATOM 16797 CE MET I 213 50.676 -41.835 14.036 1.00166.21 C +ATOM 16798 N LEU I 214 46.064 -42.235 12.391 1.00 89.36 N +ATOM 16799 CA LEU I 214 46.344 -42.147 10.961 1.00113.02 C +ATOM 16800 C LEU I 214 45.038 -42.083 10.176 1.00118.84 C +ATOM 16801 O LEU I 214 44.965 -41.468 9.113 1.00108.73 O +ATOM 16802 CB LEU I 214 47.166 -43.367 10.518 1.00138.55 C +ATOM 16803 CG LEU I 214 48.362 -43.166 9.566 1.00140.81 C +ATOM 16804 CD1 LEU I 214 49.420 -42.209 10.158 1.00162.26 C +ATOM 16805 CD2 LEU I 214 48.967 -44.535 9.222 1.00103.53 C +ATOM 16806 N CYS I 215 43.996 -42.694 10.733 1.00122.62 N +ATOM 16807 CA CYS I 215 42.648 -42.620 10.157 1.00114.75 C +ATOM 16808 C CYS I 215 42.029 -41.220 10.309 1.00 95.97 C +ATOM 16809 O CYS I 215 41.385 -40.687 9.390 1.00 54.88 O +ATOM 16810 CB CYS I 215 41.732 -43.620 10.850 1.00119.14 C +ATOM 16811 SG CYS I 215 42.219 -45.329 10.607 1.00138.20 S +ATOM 16812 N LEU I 216 42.239 -40.636 11.485 1.00 97.93 N +ATOM 16813 CA LEU I 216 41.857 -39.263 11.719 1.00 97.31 C +ATOM 16814 C LEU I 216 42.513 -38.362 10.676 1.00 99.71 C +ATOM 16815 O LEU I 216 41.831 -37.547 10.033 1.00121.50 O +ATOM 16816 CB LEU I 216 42.248 -38.817 13.131 1.00 80.95 C +ATOM 16817 CG LEU I 216 41.906 -37.357 13.457 1.00 70.44 C +ATOM 16818 CD1 LEU I 216 40.425 -37.052 13.302 1.00 69.35 C +ATOM 16819 CD2 LEU I 216 42.332 -37.046 14.882 1.00 93.64 C +ATOM 16820 N MET I 217 43.816 -38.554 10.472 1.00 78.84 N +ATOM 16821 CA MET I 217 44.564 -37.690 9.584 1.00 91.47 C +ATOM 16822 C MET I 217 44.041 -37.836 8.159 1.00104.17 C +ATOM 16823 O MET I 217 43.752 -36.837 7.480 1.00146.17 O +ATOM 16824 CB MET I 217 46.053 -37.995 9.645 1.00 96.21 C +ATOM 16825 CG MET I 217 46.927 -36.738 9.673 1.00 90.44 C +ATOM 16826 SD MET I 217 46.915 -35.853 8.092 1.00137.78 S +ATOM 16827 CE MET I 217 47.768 -34.329 8.501 1.00106.52 C +ATOM 16828 N SER I 218 43.830 -39.078 7.742 1.00101.52 N +ATOM 16829 CA SER I 218 43.279 -39.374 6.409 1.00111.65 C +ATOM 16830 C SER I 218 41.933 -38.684 6.162 1.00 85.98 C +ATOM 16831 O SER I 218 41.735 -38.019 5.146 1.00 51.82 O +ATOM 16832 CB SER I 218 43.112 -40.895 6.242 1.00125.20 C +ATOM 16833 OG SER I 218 42.812 -41.237 4.900 1.00109.79 O +ATOM 16834 N ALA I 219 41.027 -38.846 7.117 1.00 83.82 N +ATOM 16835 CA ALA I 219 39.691 -38.326 6.972 1.00 90.89 C +ATOM 16836 C ALA I 219 39.691 -36.791 6.895 1.00 87.86 C +ATOM 16837 O ALA I 219 38.868 -36.177 6.196 1.00 78.76 O +ATOM 16838 CB ALA I 219 38.834 -38.825 8.125 1.00100.59 C +ATOM 16839 N ILE I 220 40.593 -36.163 7.643 1.00 85.79 N +ATOM 16840 CA ILE I 220 40.695 -34.701 7.633 1.00 90.41 C +ATOM 16841 C ILE I 220 41.186 -34.194 6.265 1.00 91.80 C +ATOM 16842 O ILE I 220 40.646 -33.216 5.727 1.00 76.81 O +ATOM 16843 CB ILE I 220 41.619 -34.169 8.760 1.00 74.51 C +ATOM 16844 CG1 ILE I 220 40.962 -34.410 10.129 1.00 61.67 C +ATOM 16845 CG2 ILE I 220 41.946 -32.679 8.535 1.00 59.03 C +ATOM 16846 CD1 ILE I 220 41.907 -34.313 11.295 1.00 50.15 C +ATOM 16847 N GLU I 221 42.153 -34.898 5.685 1.00 93.27 N +ATOM 16848 CA GLU I 221 42.621 -34.583 4.337 1.00115.54 C +ATOM 16849 C GLU I 221 41.454 -34.651 3.331 1.00131.07 C +ATOM 16850 O GLU I 221 41.217 -33.694 2.567 1.00124.22 O +ATOM 16851 CB GLU I 221 43.734 -35.550 3.925 1.00106.52 C +ATOM 16852 CG GLU I 221 45.054 -35.287 4.621 1.00 93.47 C +ATOM 16853 CD GLU I 221 46.019 -36.463 4.561 1.00106.38 C +ATOM 16854 OE1 GLU I 221 45.581 -37.648 4.597 1.00106.61 O +ATOM 16855 OE2 GLU I 221 47.234 -36.189 4.450 1.00 99.57 O +ATOM 16856 N THR I 222 40.727 -35.773 3.363 1.00101.79 N +ATOM 16857 CA THR I 222 39.557 -35.996 2.516 1.00 85.54 C +ATOM 16858 C THR I 222 38.548 -34.850 2.635 1.00 81.29 C +ATOM 16859 O THR I 222 38.080 -34.313 1.626 1.00 61.33 O +ATOM 16860 CB THR I 222 38.852 -37.296 2.930 1.00 89.99 C +ATOM 16861 OG1 THR I 222 39.641 -38.432 2.541 1.00 89.36 O +ATOM 16862 CG2 THR I 222 37.428 -37.374 2.322 1.00 93.09 C +ATOM 16863 N GLY I 223 38.237 -34.479 3.878 1.00 73.17 N +ATOM 16864 CA GLY I 223 37.401 -33.318 4.154 1.00 72.10 C +ATOM 16865 C GLY I 223 37.898 -32.014 3.518 1.00 79.20 C +ATOM 16866 O GLY I 223 37.106 -31.236 2.977 1.00 83.62 O +ATOM 16867 N VAL I 224 39.210 -31.787 3.549 1.00 81.06 N +ATOM 16868 CA VAL I 224 39.777 -30.586 2.957 1.00 91.34 C +ATOM 16869 C VAL I 224 39.547 -30.584 1.452 1.00 95.27 C +ATOM 16870 O VAL I 224 39.191 -29.552 0.877 1.00 95.21 O +ATOM 16871 CB VAL I 224 41.282 -30.468 3.230 1.00118.01 C +ATOM 16872 CG1 VAL I 224 41.877 -29.296 2.457 1.00113.63 C +ATOM 16873 CG2 VAL I 224 41.538 -30.307 4.722 1.00137.62 C +ATOM 16874 N ILE I 225 39.734 -31.738 0.817 1.00 86.75 N +ATOM 16875 CA ILE I 225 39.485 -31.841 -0.616 1.00 85.34 C +ATOM 16876 C ILE I 225 38.037 -31.484 -0.917 1.00 87.27 C +ATOM 16877 O ILE I 225 37.778 -30.646 -1.787 1.00 73.29 O +ATOM 16878 CB ILE I 225 39.817 -33.245 -1.167 1.00 90.83 C +ATOM 16879 CG1 ILE I 225 41.324 -33.477 -1.102 1.00113.44 C +ATOM 16880 CG2 ILE I 225 39.362 -33.381 -2.609 1.00 77.02 C +ATOM 16881 CD1 ILE I 225 41.721 -34.932 -1.209 1.00136.69 C +ATOM 16882 N PHE I 226 37.093 -32.148 -0.234 1.00 83.60 N +ATOM 16883 CA PHE I 226 35.654 -31.890 -0.452 1.00 85.59 C +ATOM 16884 C PHE I 226 35.318 -30.394 -0.266 1.00 84.93 C +ATOM 16885 O PHE I 226 34.430 -29.869 -0.926 1.00 79.47 O +ATOM 16886 CB PHE I 226 34.772 -32.752 0.478 1.00 79.88 C +ATOM 16887 CG PHE I 226 34.570 -34.178 0.025 1.00 80.91 C +ATOM 16888 CD1 PHE I 226 33.957 -34.457 -1.192 1.00101.83 C +ATOM 16889 CD2 PHE I 226 34.902 -35.243 0.856 1.00 80.34 C +ATOM 16890 CE1 PHE I 226 33.750 -35.769 -1.612 1.00 81.52 C +ATOM 16891 CE2 PHE I 226 34.672 -36.545 0.459 1.00 83.22 C +ATOM 16892 CZ PHE I 226 34.111 -36.807 -0.791 1.00 85.14 C +ATOM 16893 N LEU I 227 36.000 -29.741 0.670 1.00 77.13 N +ATOM 16894 CA LEU I 227 35.801 -28.321 0.915 1.00 72.36 C +ATOM 16895 C LEU I 227 36.284 -27.482 -0.253 1.00 78.19 C +ATOM 16896 O LEU I 227 35.598 -26.579 -0.683 1.00 65.93 O +ATOM 16897 CB LEU I 227 36.553 -27.929 2.168 1.00 88.67 C +ATOM 16898 CG LEU I 227 35.896 -28.303 3.501 1.00 92.61 C +ATOM 16899 CD1 LEU I 227 36.790 -28.162 4.728 1.00 79.79 C +ATOM 16900 CD2 LEU I 227 34.619 -27.516 3.708 1.00 94.88 C +ATOM 16901 N ILE I 228 37.441 -27.834 -0.811 1.00101.04 N +ATOM 16902 CA ILE I 228 37.993 -27.098 -1.943 1.00100.93 C +ATOM 16903 C ILE I 228 37.081 -27.281 -3.139 1.00 99.29 C +ATOM 16904 O ILE I 228 36.749 -26.312 -3.832 1.00111.04 O +ATOM 16905 CB ILE I 228 39.424 -27.566 -2.328 1.00 99.44 C +ATOM 16906 CG1 ILE I 228 40.409 -27.275 -1.196 1.00107.64 C +ATOM 16907 CG2 ILE I 228 39.905 -26.832 -3.566 1.00 90.12 C +ATOM 16908 CD1 ILE I 228 41.733 -27.996 -1.309 1.00 96.22 C +ATOM 16909 N ASN I 229 36.697 -28.526 -3.401 1.00 77.95 N +ATOM 16910 CA ASN I 229 35.872 -28.832 -4.560 1.00 96.14 C +ATOM 16911 C ASN I 229 34.546 -28.092 -4.444 1.00 84.68 C +ATOM 16912 O ASN I 229 34.046 -27.512 -5.424 1.00 74.17 O +ATOM 16913 CB ASN I 229 35.663 -30.358 -4.664 1.00121.34 C +ATOM 16914 CG ASN I 229 35.161 -30.815 -6.033 1.00130.14 C +ATOM 16915 OD1 ASN I 229 35.300 -30.099 -7.029 1.00166.45 O +ATOM 16916 ND2 ASN I 229 34.534 -31.992 -6.070 1.00 94.63 N +ATOM 16917 N ASP I 230 33.971 -28.140 -3.251 1.00 64.93 N +ATOM 16918 CA ASP I 230 32.712 -27.475 -3.007 1.00 70.83 C +ATOM 16919 C ASP I 230 32.852 -25.983 -3.276 1.00 74.73 C +ATOM 16920 O ASP I 230 31.952 -25.329 -3.799 1.00 81.34 O +ATOM 16921 CB ASP I 230 32.267 -27.729 -1.576 1.00 83.89 C +ATOM 16922 CG ASP I 230 30.889 -27.156 -1.287 1.00117.67 C +ATOM 16923 OD1 ASP I 230 29.900 -27.755 -1.755 1.00131.80 O +ATOM 16924 OD2 ASP I 230 30.787 -26.154 -0.530 1.00209.06 O +ATOM 16925 N GLY I 231 33.962 -25.419 -2.831 1.00112.41 N +ATOM 16926 CA GLY I 231 34.193 -23.986 -2.975 1.00126.71 C +ATOM 16927 C GLY I 231 34.329 -23.627 -4.445 1.00 99.28 C +ATOM 16928 O GLY I 231 33.983 -22.502 -4.847 1.00 81.76 O +ATOM 16929 N ILE I 232 34.901 -24.554 -5.219 1.00 77.99 N +ATOM 16930 CA ILE I 232 35.124 -24.317 -6.634 1.00101.27 C +ATOM 16931 C ILE I 232 33.765 -24.210 -7.279 1.00125.39 C +ATOM 16932 O ILE I 232 33.508 -23.268 -8.040 1.00132.98 O +ATOM 16933 CB ILE I 232 35.950 -25.450 -7.283 1.00112.89 C +ATOM 16934 CG1 ILE I 232 37.432 -25.300 -6.909 1.00117.54 C +ATOM 16935 CG2 ILE I 232 35.788 -25.453 -8.808 1.00137.38 C +ATOM 16936 CD1 ILE I 232 38.253 -26.553 -7.126 1.00116.11 C +ATOM 16937 N ASP I 233 32.901 -25.178 -6.976 1.00141.96 N +ATOM 16938 CA ASP I 233 31.527 -25.195 -7.501 1.00165.70 C +ATOM 16939 C ASP I 233 30.767 -23.918 -7.145 1.00143.87 C +ATOM 16940 O ASP I 233 30.174 -23.278 -8.008 1.00142.36 O +ATOM 16941 CB ASP I 233 30.753 -26.399 -6.952 1.00181.20 C +ATOM 16942 CG ASP I 233 31.302 -27.740 -7.437 1.00180.45 C +ATOM 16943 OD1 ASP I 233 32.401 -27.764 -8.037 1.00177.49 O +ATOM 16944 OD2 ASP I 233 30.637 -28.774 -7.183 1.00139.93 O +ATOM 16945 N ARG I 234 30.836 -23.529 -5.880 1.00137.72 N +ATOM 16946 CA ARG I 234 30.068 -22.398 -5.391 1.00143.48 C +ATOM 16947 C ARG I 234 30.684 -21.018 -5.678 1.00155.85 C +ATOM 16948 O ARG I 234 30.107 -19.981 -5.317 1.00198.73 O +ATOM 16949 CB ARG I 234 29.837 -22.561 -3.893 1.00159.06 C +ATOM 16950 CG ARG I 234 28.837 -23.656 -3.599 1.00151.57 C +ATOM 16951 CD ARG I 234 28.959 -24.192 -2.188 1.00157.73 C +ATOM 16952 NE ARG I 234 28.005 -25.290 -2.043 1.00161.87 N +ATOM 16953 CZ ARG I 234 27.016 -25.324 -1.158 1.00175.12 C +ATOM 16954 NH1 ARG I 234 26.916 -24.356 -0.248 1.00220.40 N +ATOM 16955 NH2 ARG I 234 26.145 -26.335 -1.163 1.00123.05 N +ATOM 16956 N GLY I 235 31.851 -20.996 -6.313 1.00147.73 N +ATOM 16957 CA GLY I 235 32.483 -19.737 -6.709 1.00132.24 C +ATOM 16958 C GLY I 235 33.152 -18.985 -5.575 1.00 96.14 C +ATOM 16959 O GLY I 235 33.176 -17.755 -5.583 1.00 50.54 O +ATOM 16960 N LEU I 236 33.672 -19.724 -4.588 1.00102.68 N +ATOM 16961 CA LEU I 236 34.506 -19.112 -3.545 1.00107.38 C +ATOM 16962 C LEU I 236 35.860 -18.803 -4.148 1.00106.19 C +ATOM 16963 O LEU I 236 36.372 -17.687 -4.008 1.00138.02 O +ATOM 16964 CB LEU I 236 34.689 -20.026 -2.317 1.00115.06 C +ATOM 16965 CG LEU I 236 33.592 -20.015 -1.242 1.00126.41 C +ATOM 16966 CD1 LEU I 236 32.392 -20.856 -1.667 1.00126.63 C +ATOM 16967 CD2 LEU I 236 34.144 -20.538 0.070 1.00129.64 C +ATOM 16968 N TRP I 237 36.428 -19.786 -4.838 1.00 89.40 N +ATOM 16969 CA TRP I 237 37.745 -19.632 -5.447 1.00 91.87 C +ATOM 16970 C TRP I 237 37.774 -20.282 -6.829 1.00112.84 C +ATOM 16971 O TRP I 237 36.872 -21.046 -7.182 1.00106.50 O +ATOM 16972 CB TRP I 237 38.812 -20.227 -4.538 1.00 84.24 C +ATOM 16973 CG TRP I 237 38.322 -21.402 -3.773 1.00 88.41 C +ATOM 16974 CD1 TRP I 237 38.017 -22.624 -4.276 1.00101.14 C +ATOM 16975 CD2 TRP I 237 38.115 -21.488 -2.356 1.00102.39 C +ATOM 16976 NE1 TRP I 237 37.640 -23.479 -3.264 1.00105.92 N +ATOM 16977 CE2 TRP I 237 37.704 -22.812 -2.074 1.00102.91 C +ATOM 16978 CE3 TRP I 237 38.235 -20.579 -1.300 1.00120.44 C +ATOM 16979 CZ2 TRP I 237 37.399 -23.247 -0.789 1.00115.62 C +ATOM 16980 CZ3 TRP I 237 37.914 -21.006 -0.021 1.00131.20 C +ATOM 16981 CH2 TRP I 237 37.502 -22.331 0.222 1.00147.03 C +ATOM 16982 N ASP I 238 38.800 -19.953 -7.614 1.00135.52 N +ATOM 16983 CA ASP I 238 38.864 -20.365 -9.018 1.00149.44 C +ATOM 16984 C ASP I 238 40.184 -21.036 -9.387 1.00136.39 C +ATOM 16985 O ASP I 238 41.247 -20.687 -8.863 1.00 96.75 O +ATOM 16986 CB ASP I 238 38.627 -19.173 -9.949 1.00145.47 C +ATOM 16987 CG ASP I 238 37.304 -18.477 -9.678 1.00140.13 C +ATOM 16988 OD1 ASP I 238 37.253 -17.681 -8.724 1.00124.30 O +ATOM 16989 OD2 ASP I 238 36.320 -18.714 -10.412 1.00124.09 O +ATOM 16990 N LEU I 239 40.102 -21.971 -10.333 1.00147.31 N +ATOM 16991 CA LEU I 239 41.266 -22.711 -10.798 1.00167.94 C +ATOM 16992 C LEU I 239 42.111 -21.852 -11.731 1.00182.80 C +ATOM 16993 O LEU I 239 41.585 -21.044 -12.499 1.00138.66 O +ATOM 16994 CB LEU I 239 40.842 -23.992 -11.533 1.00166.55 C +ATOM 16995 CG LEU I 239 40.364 -25.203 -10.733 1.00154.83 C +ATOM 16996 CD1 LEU I 239 40.099 -26.389 -11.651 1.00155.95 C +ATOM 16997 CD2 LEU I 239 41.385 -25.581 -9.680 1.00162.70 C +ATOM 16998 N GLN I 240 43.427 -22.039 -11.648 1.00184.96 N +ATOM 16999 CA GLN I 240 44.350 -21.451 -12.611 1.00162.43 C +ATOM 17000 C GLN I 240 43.936 -21.841 -14.031 1.00159.39 C +ATOM 17001 O GLN I 240 43.693 -20.980 -14.880 1.00154.60 O +ATOM 17002 CB GLN I 240 45.788 -21.917 -12.325 1.00142.59 C +ATOM 17003 CG GLN I 240 46.846 -21.205 -13.160 1.00136.97 C +ATOM 17004 CD GLN I 240 46.936 -19.724 -12.836 1.00151.59 C +ATOM 17005 OE1 GLN I 240 47.542 -19.332 -11.835 1.00178.81 O +ATOM 17006 NE2 GLN I 240 46.275 -18.894 -13.644 1.00148.79 N +ATOM 17007 N ASN I 241 43.851 -23.147 -14.266 1.00167.80 N +ATOM 17008 CA ASN I 241 43.459 -23.699 -15.558 1.00158.01 C +ATOM 17009 C ASN I 241 42.036 -24.223 -15.517 1.00151.45 C +ATOM 17010 O ASN I 241 41.764 -25.254 -14.888 1.00148.30 O +ATOM 17011 CB ASN I 241 44.393 -24.845 -15.942 1.00157.36 C +ATOM 17012 CG ASN I 241 45.444 -24.423 -16.937 1.00175.64 C +ATOM 17013 OD1 ASN I 241 45.320 -24.707 -18.124 1.00186.11 O +ATOM 17014 ND2 ASN I 241 46.476 -23.720 -16.466 1.00187.21 N +ATOM 17015 N LYS I 242 41.138 -23.530 -16.212 1.00133.37 N +ATOM 17016 CA LYS I 242 39.737 -23.930 -16.256 1.00114.95 C +ATOM 17017 C LYS I 242 39.607 -25.275 -16.964 1.00128.79 C +ATOM 17018 O LYS I 242 38.678 -26.049 -16.692 1.00109.54 O +ATOM 17019 CB LYS I 242 38.895 -22.860 -16.949 1.00109.32 C +ATOM 17020 CG LYS I 242 39.144 -21.450 -16.427 1.00113.38 C +ATOM 17021 CD LYS I 242 37.858 -20.774 -15.986 1.00134.57 C +ATOM 17022 CE LYS I 242 38.026 -20.104 -14.629 1.00144.33 C +ATOM 17023 NZ LYS I 242 36.834 -19.300 -14.235 1.00152.26 N +ATOM 17024 N ALA I 243 40.590 -25.556 -17.825 1.00154.92 N +ATOM 17025 CA ALA I 243 40.729 -26.843 -18.504 1.00168.44 C +ATOM 17026 C ALA I 243 40.953 -27.982 -17.516 1.00179.04 C +ATOM 17027 O ALA I 243 40.747 -29.153 -17.861 1.00188.58 O +ATOM 17028 CB ALA I 243 41.883 -26.791 -19.501 1.00151.81 C +ATOM 17029 N GLU I 244 41.393 -27.651 -16.300 1.00173.23 N +ATOM 17030 CA GLU I 244 41.681 -28.680 -15.306 1.00172.02 C +ATOM 17031 C GLU I 244 40.486 -28.981 -14.406 1.00149.79 C +ATOM 17032 O GLU I 244 40.640 -29.670 -13.410 1.00130.86 O +ATOM 17033 CB GLU I 244 42.894 -28.290 -14.455 1.00155.45 C +ATOM 17034 CG GLU I 244 44.218 -28.389 -15.185 1.00138.54 C +ATOM 17035 CD GLU I 244 45.402 -28.257 -14.250 1.00142.17 C +ATOM 17036 OE1 GLU I 244 45.724 -27.117 -13.843 1.00137.67 O +ATOM 17037 OE2 GLU I 244 46.040 -29.294 -13.949 1.00162.68 O +ATOM 17038 N ARG I 245 39.309 -28.469 -14.755 1.00130.77 N +ATOM 17039 CA ARG I 245 38.097 -28.810 -14.027 1.00128.61 C +ATOM 17040 C ARG I 245 37.850 -30.317 -13.977 1.00127.75 C +ATOM 17041 O ARG I 245 37.319 -30.822 -12.984 1.00136.78 O +ATOM 17042 CB ARG I 245 36.872 -28.123 -14.618 1.00130.32 C +ATOM 17043 CG ARG I 245 35.608 -28.300 -13.774 1.00141.13 C +ATOM 17044 CD ARG I 245 34.401 -27.520 -14.316 1.00162.13 C +ATOM 17045 NE ARG I 245 34.239 -26.244 -13.613 1.00203.38 N +ATOM 17046 CZ ARG I 245 33.815 -26.115 -12.355 1.00195.04 C +ATOM 17047 NH1 ARG I 245 33.527 -27.181 -11.634 1.00174.75 N +ATOM 17048 NH2 ARG I 245 33.683 -24.911 -11.811 1.00193.17 N +ATOM 17049 N GLN I 246 38.157 -31.021 -15.065 1.00130.75 N +ATOM 17050 CA GLN I 246 37.845 -32.453 -15.148 1.00146.29 C +ATOM 17051 C GLN I 246 39.018 -33.297 -14.673 1.00134.48 C +ATOM 17052 O GLN I 246 39.144 -34.465 -15.051 1.00150.16 O +ATOM 17053 CB GLN I 246 37.421 -32.858 -16.573 1.00156.62 C +ATOM 17054 CG GLN I 246 36.045 -32.362 -16.991 1.00156.97 C +ATOM 17055 CD GLN I 246 36.046 -30.886 -17.324 1.00186.07 C +ATOM 17056 OE1 GLN I 246 36.937 -30.396 -18.028 1.00173.00 O +ATOM 17057 NE2 GLN I 246 35.034 -30.169 -16.842 1.00204.70 N +ATOM 17058 N ASN I 247 39.892 -32.683 -13.880 1.00116.67 N +ATOM 17059 CA ASN I 247 40.964 -33.396 -13.173 1.00126.72 C +ATOM 17060 C ASN I 247 40.458 -34.699 -12.556 1.00107.26 C +ATOM 17061 O ASN I 247 39.352 -34.738 -12.014 1.00128.97 O +ATOM 17062 CB ASN I 247 41.508 -32.496 -12.068 1.00136.63 C +ATOM 17063 CG ASN I 247 42.926 -32.826 -11.688 1.00154.97 C +ATOM 17064 OD1 ASN I 247 43.181 -33.382 -10.612 1.00179.25 O +ATOM 17065 ND2 ASN I 247 43.862 -32.496 -12.573 1.00155.77 N +ATOM 17066 N ASP I 248 41.255 -35.762 -12.659 1.00106.02 N +ATOM 17067 CA ASP I 248 40.852 -37.100 -12.181 1.00144.22 C +ATOM 17068 C ASP I 248 40.390 -37.057 -10.724 1.00166.30 C +ATOM 17069 O ASP I 248 39.356 -37.634 -10.354 1.00179.65 O +ATOM 17070 CB ASP I 248 42.024 -38.088 -12.289 1.00156.22 C +ATOM 17071 CG ASP I 248 42.341 -38.482 -13.724 1.00157.49 C +ATOM 17072 OD1 ASP I 248 41.406 -38.661 -14.524 1.00133.56 O +ATOM 17073 OD2 ASP I 248 43.537 -38.638 -14.039 1.00168.44 O +ATOM 17074 N ILE I 249 41.175 -36.369 -9.901 1.00170.49 N +ATOM 17075 CA ILE I 249 40.915 -36.281 -8.472 1.00142.34 C +ATOM 17076 C ILE I 249 39.619 -35.498 -8.227 1.00122.00 C +ATOM 17077 O ILE I 249 38.728 -35.956 -7.505 1.00132.05 O +ATOM 17078 CB ILE I 249 42.103 -35.609 -7.747 1.00133.66 C +ATOM 17079 CG1 ILE I 249 43.374 -36.455 -7.904 1.00124.05 C +ATOM 17080 CG2 ILE I 249 41.791 -35.432 -6.277 1.00138.91 C +ATOM 17081 CD1 ILE I 249 44.657 -35.686 -7.669 1.00117.73 C +ATOM 17082 N LEU I 250 39.511 -34.328 -8.855 1.00109.10 N +ATOM 17083 CA LEU I 250 38.348 -33.453 -8.676 1.00103.39 C +ATOM 17084 C LEU I 250 37.030 -34.101 -9.093 1.00108.27 C +ATOM 17085 O LEU I 250 36.012 -33.927 -8.424 1.00136.16 O +ATOM 17086 CB LEU I 250 38.534 -32.154 -9.449 1.00103.25 C +ATOM 17087 CG LEU I 250 39.433 -31.112 -8.773 1.00102.94 C +ATOM 17088 CD1 LEU I 250 39.793 -29.980 -9.721 1.00106.33 C +ATOM 17089 CD2 LEU I 250 38.744 -30.557 -7.546 1.00110.01 C +ATOM 17090 N VAL I 251 37.060 -34.878 -10.170 1.00117.00 N +ATOM 17091 CA VAL I 251 35.869 -35.604 -10.613 1.00121.83 C +ATOM 17092 C VAL I 251 35.582 -36.834 -9.741 1.00134.15 C +ATOM 17093 O VAL I 251 34.436 -37.298 -9.657 1.00196.37 O +ATOM 17094 CB VAL I 251 35.961 -36.032 -12.095 1.00125.86 C +ATOM 17095 CG1 VAL I 251 36.256 -34.824 -12.974 1.00113.10 C +ATOM 17096 CG2 VAL I 251 37.001 -37.138 -12.301 1.00129.78 C +ATOM 17097 N LYS I 252 36.621 -37.376 -9.111 1.00117.65 N +ATOM 17098 CA LYS I 252 36.455 -38.499 -8.188 1.00113.82 C +ATOM 17099 C LYS I 252 35.666 -38.054 -6.936 1.00107.93 C +ATOM 17100 O LYS I 252 34.714 -38.712 -6.521 1.00 83.06 O +ATOM 17101 CB LYS I 252 37.832 -39.054 -7.824 1.00115.98 C +ATOM 17102 CG LYS I 252 37.826 -40.207 -6.835 1.00121.04 C +ATOM 17103 CD LYS I 252 39.261 -40.639 -6.534 1.00133.99 C +ATOM 17104 CE LYS I 252 39.506 -40.803 -5.041 1.00141.96 C +ATOM 17105 NZ LYS I 252 40.948 -40.970 -4.698 1.00127.72 N +ATOM 17106 N TYR I 253 36.037 -36.897 -6.386 1.00123.42 N +ATOM 17107 CA TYR I 253 35.391 -36.352 -5.174 1.00101.46 C +ATOM 17108 C TYR I 253 34.063 -35.712 -5.519 1.00 88.80 C +ATOM 17109 O TYR I 253 33.130 -35.743 -4.728 1.00102.11 O +ATOM 17110 CB TYR I 253 36.315 -35.343 -4.456 1.00 88.75 C +ATOM 17111 CG TYR I 253 37.483 -36.008 -3.749 1.00 91.15 C +ATOM 17112 CD1 TYR I 253 37.332 -36.578 -2.506 1.00 83.25 C +ATOM 17113 CD2 TYR I 253 38.704 -36.187 -4.396 1.00114.71 C +ATOM 17114 CE1 TYR I 253 38.374 -37.265 -1.906 1.00 96.71 C +ATOM 17115 CE2 TYR I 253 39.745 -36.890 -3.802 1.00112.48 C +ATOM 17116 CZ TYR I 253 39.570 -37.420 -2.549 1.00 95.55 C +ATOM 17117 OH TYR I 253 40.611 -38.109 -1.940 1.00111.30 O +ATOM 17118 N ARG I 254 33.982 -35.138 -6.712 1.00 94.52 N +ATOM 17119 CA ARG I 254 32.709 -34.686 -7.257 1.00 95.08 C +ATOM 17120 C ARG I 254 31.722 -35.855 -7.306 1.00 83.68 C +ATOM 17121 O ARG I 254 30.530 -35.689 -7.040 1.00 81.87 O +ATOM 17122 CB ARG I 254 32.899 -34.095 -8.667 1.00116.65 C +ATOM 17123 CG ARG I 254 31.633 -33.490 -9.250 1.00121.63 C +ATOM 17124 CD ARG I 254 31.907 -32.562 -10.419 1.00123.87 C +ATOM 17125 NE ARG I 254 32.649 -31.368 -10.035 1.00112.80 N +ATOM 17126 CZ ARG I 254 33.922 -31.132 -10.329 1.00135.42 C +ATOM 17127 NH1 ARG I 254 34.645 -32.015 -11.011 1.00136.13 N +ATOM 17128 NH2 ARG I 254 34.485 -29.988 -9.943 1.00147.60 N +ATOM 17129 N HIS I 255 32.218 -37.026 -7.691 1.00 90.43 N +ATOM 17130 CA HIS I 255 31.377 -38.217 -7.832 1.00120.70 C +ATOM 17131 C HIS I 255 30.896 -38.721 -6.482 1.00117.67 C +ATOM 17132 O HIS I 255 29.800 -39.266 -6.375 1.00135.35 O +ATOM 17133 CB HIS I 255 32.123 -39.333 -8.598 1.00150.00 C +ATOM 17134 CG HIS I 255 31.623 -39.551 -9.992 1.00159.25 C +ATOM 17135 ND1 HIS I 255 31.914 -38.690 -11.030 1.00160.48 N +ATOM 17136 CD2 HIS I 255 30.862 -40.538 -10.521 1.00163.42 C +ATOM 17137 CE1 HIS I 255 31.354 -39.139 -12.138 1.00175.32 C +ATOM 17138 NE2 HIS I 255 30.707 -40.257 -11.856 1.00183.15 N +ATOM 17139 N MET I 256 31.735 -38.589 -5.459 1.00129.27 N +ATOM 17140 CA MET I 256 31.356 -39.066 -4.124 1.00132.17 C +ATOM 17141 C MET I 256 30.221 -38.218 -3.532 1.00131.49 C +ATOM 17142 O MET I 256 29.461 -38.701 -2.695 1.00123.86 O +ATOM 17143 CB MET I 256 32.579 -39.102 -3.199 1.00134.65 C +ATOM 17144 CG MET I 256 33.763 -39.899 -3.761 1.00132.73 C +ATOM 17145 SD MET I 256 35.000 -40.435 -2.562 1.00106.72 S +ATOM 17146 CE MET I 256 34.054 -41.664 -1.639 1.00 89.83 C +ATOM 17147 N SER I 257 30.070 -36.988 -4.036 1.00145.82 N +ATOM 17148 CA SER I 257 28.958 -36.090 -3.659 1.00124.58 C +ATOM 17149 C SER I 257 27.635 -36.446 -4.341 1.00 98.41 C +ATOM 17150 O SER I 257 26.904 -37.294 -3.849 1.00 74.00 O +ATOM 17151 CB SER I 257 29.305 -34.632 -3.998 1.00116.88 C +ATOM 17152 OG SER I 257 30.644 -34.318 -3.648 1.00103.50 O +TER 17153 SER I 257 +ATOM 17154 N LEU J 2 24.473 55.453 3.734 1.00129.33 N +ATOM 17155 CA LEU J 2 25.669 55.301 4.626 1.00126.24 C +ATOM 17156 C LEU J 2 25.224 55.025 6.078 1.00140.10 C +ATOM 17157 O LEU J 2 25.364 55.877 6.989 1.00113.69 O +ATOM 17158 CB LEU J 2 26.594 56.529 4.545 1.00122.00 C +ATOM 17159 CG LEU J 2 27.255 56.881 3.186 1.00122.32 C +ATOM 17160 CD1 LEU J 2 28.094 58.150 3.349 1.00100.48 C +ATOM 17161 CD2 LEU J 2 28.093 55.753 2.555 1.00 94.36 C +ATOM 17162 N THR J 3 24.566 53.868 6.228 1.00177.08 N +ATOM 17163 CA THR J 3 24.374 53.185 7.520 1.00160.32 C +ATOM 17164 C THR J 3 24.543 51.662 7.354 1.00134.85 C +ATOM 17165 O THR J 3 24.488 50.910 8.325 1.00113.79 O +ATOM 17166 CB THR J 3 22.979 53.450 8.132 1.00130.04 C +ATOM 17167 OG1 THR J 3 21.976 52.793 7.345 1.00142.83 O +ATOM 17168 CG2 THR J 3 22.702 54.959 8.242 1.00108.13 C +ATOM 17169 N ALA J 4 24.722 51.219 6.113 1.00117.83 N +ATOM 17170 CA ALA J 4 25.355 49.936 5.852 1.00112.66 C +ATOM 17171 C ALA J 4 26.866 50.073 6.115 1.00107.12 C +ATOM 17172 O ALA J 4 27.326 51.108 6.584 1.00 92.31 O +ATOM 17173 CB ALA J 4 25.083 49.485 4.424 1.00134.42 C +ATOM 17174 N PRO J 5 27.651 49.012 5.886 1.00128.56 N +ATOM 17175 CA PRO J 5 28.944 49.123 6.554 1.00141.72 C +ATOM 17176 C PRO J 5 29.949 49.918 5.726 1.00136.00 C +ATOM 17177 O PRO J 5 29.670 50.235 4.569 1.00 77.56 O +ATOM 17178 CB PRO J 5 29.392 47.669 6.689 1.00150.47 C +ATOM 17179 CG PRO J 5 28.703 46.933 5.574 1.00157.57 C +ATOM 17180 CD PRO J 5 27.508 47.744 5.146 1.00143.67 C +ATOM 17181 N PRO J 6 31.098 50.260 6.333 1.00115.76 N +ATOM 17182 CA PRO J 6 32.248 50.765 5.582 1.00107.48 C +ATOM 17183 C PRO J 6 33.077 49.654 4.969 1.00103.34 C +ATOM 17184 O PRO J 6 33.102 48.544 5.488 1.00102.60 O +ATOM 17185 CB PRO J 6 33.062 51.524 6.629 1.00119.53 C +ATOM 17186 CG PRO J 6 32.590 51.049 7.957 1.00113.31 C +ATOM 17187 CD PRO J 6 31.260 50.378 7.793 1.00 97.56 C +ATOM 17188 N LYS J 7 33.741 49.934 3.853 1.00114.07 N +ATOM 17189 CA LYS J 7 34.564 48.912 3.188 1.00133.21 C +ATOM 17190 C LYS J 7 36.037 49.008 3.574 1.00137.50 C +ATOM 17191 O LYS J 7 36.471 49.975 4.213 1.00 77.01 O +ATOM 17192 CB LYS J 7 34.427 48.973 1.668 1.00125.33 C +ATOM 17193 CG LYS J 7 33.069 48.577 1.149 1.00128.22 C +ATOM 17194 CD LYS J 7 32.226 49.777 0.728 1.00147.09 C +ATOM 17195 CE LYS J 7 31.023 49.324 -0.083 1.00165.54 C +ATOM 17196 NZ LYS J 7 29.869 50.252 0.054 1.00168.32 N +ATOM 17197 N GLU J 8 36.794 47.975 3.199 1.00171.47 N +ATOM 17198 CA GLU J 8 38.153 47.782 3.714 1.00182.38 C +ATOM 17199 C GLU J 8 39.158 48.831 3.207 1.00151.75 C +ATOM 17200 O GLU J 8 39.363 48.974 2.019 1.00153.43 O +ATOM 17201 CB GLU J 8 38.637 46.357 3.460 1.00191.75 C +ATOM 17202 CG GLU J 8 38.705 45.523 4.774 1.00209.11 C +ATOM 17203 CD GLU J 8 37.712 44.357 4.861 1.00185.81 C +ATOM 17204 OE1 GLU J 8 36.540 44.582 4.471 1.00209.55 O +ATOM 17205 OE2 GLU J 8 38.076 43.262 5.404 1.00 99.10 O +ATOM 17206 N ALA J 9 39.694 49.626 4.128 1.00125.21 N +ATOM 17207 CA ALA J 9 40.728 50.607 3.833 1.00 90.99 C +ATOM 17208 C ALA J 9 42.116 50.028 4.171 1.00 92.93 C +ATOM 17209 O ALA J 9 42.428 49.769 5.334 1.00 89.80 O +ATOM 17210 CB ALA J 9 40.474 51.862 4.642 1.00 79.94 C +ATOM 17211 N ALA J 10 42.921 49.803 3.138 1.00 86.70 N +ATOM 17212 CA ALA J 10 44.216 49.099 3.221 1.00 89.23 C +ATOM 17213 C ALA J 10 44.024 47.594 3.110 1.00 95.50 C +ATOM 17214 O ALA J 10 42.940 47.074 3.373 1.00 99.32 O +ATOM 17215 CB ALA J 10 45.012 49.470 4.474 1.00 77.21 C +ATOM 17216 N ARG J 11 45.080 46.904 2.678 1.00106.96 N +ATOM 17217 CA ARG J 11 44.979 45.509 2.219 1.00118.01 C +ATOM 17218 C ARG J 11 45.594 44.546 3.222 1.00 89.07 C +ATOM 17219 O ARG J 11 46.556 44.888 3.906 1.00117.49 O +ATOM 17220 CB ARG J 11 45.698 45.340 0.864 1.00141.37 C +ATOM 17221 CG ARG J 11 47.213 45.497 0.921 1.00158.80 C +ATOM 17222 CD ARG J 11 47.786 46.004 -0.404 1.00175.63 C +ATOM 17223 NE ARG J 11 48.338 47.357 -0.282 1.00187.16 N +ATOM 17224 CZ ARG J 11 48.946 48.010 -1.268 1.00195.23 C +ATOM 17225 NH1 ARG J 11 49.089 47.429 -2.451 1.00235.85 N +ATOM 17226 NH2 ARG J 11 49.416 49.238 -1.077 1.00174.08 N +ATOM 17227 N PRO J 12 45.081 43.321 3.285 1.00 64.87 N +ATOM 17228 CA PRO J 12 45.880 42.301 3.927 1.00 80.46 C +ATOM 17229 C PRO J 12 47.216 42.053 3.205 1.00 83.11 C +ATOM 17230 O PRO J 12 47.237 41.555 2.091 1.00 78.33 O +ATOM 17231 CB PRO J 12 44.977 41.033 3.874 1.00 76.28 C +ATOM 17232 CG PRO J 12 43.646 41.508 3.439 1.00 71.42 C +ATOM 17233 CD PRO J 12 43.908 42.745 2.630 1.00 71.43 C +ATOM 17234 N THR J 13 48.315 42.364 3.880 1.00 97.18 N +ATOM 17235 CA THR J 13 49.634 41.881 3.496 1.00116.67 C +ATOM 17236 C THR J 13 50.028 40.626 4.299 1.00105.17 C +ATOM 17237 O THR J 13 49.485 40.396 5.380 1.00189.00 O +ATOM 17238 CB THR J 13 50.669 42.989 3.742 1.00127.87 C +ATOM 17239 OG1 THR J 13 51.918 42.608 3.151 1.00125.50 O +ATOM 17240 CG2 THR J 13 50.854 43.278 5.275 1.00126.46 C +ATOM 17241 N LEU J 14 51.006 39.850 3.846 1.00 82.08 N +ATOM 17242 CA LEU J 14 51.588 38.848 4.764 1.00118.54 C +ATOM 17243 C LEU J 14 52.503 39.553 5.790 1.00138.42 C +ATOM 17244 O LEU J 14 52.851 40.703 5.597 1.00132.45 O +ATOM 17245 CB LEU J 14 52.269 37.681 4.049 1.00 99.34 C +ATOM 17246 CG LEU J 14 53.334 38.007 3.040 1.00105.86 C +ATOM 17247 CD1 LEU J 14 54.387 36.920 3.020 1.00 94.60 C +ATOM 17248 CD2 LEU J 14 52.682 38.121 1.679 1.00130.19 C +ATOM 17249 N MET J 15 52.764 38.934 6.942 1.00151.82 N +ATOM 17250 CA MET J 15 53.107 39.702 8.158 1.00119.81 C +ATOM 17251 C MET J 15 54.489 40.343 8.031 1.00 93.43 C +ATOM 17252 O MET J 15 55.472 39.654 7.788 1.00 56.94 O +ATOM 17253 CB MET J 15 53.034 38.836 9.435 1.00117.28 C +ATOM 17254 CG MET J 15 52.679 39.629 10.696 1.00 99.67 C +ATOM 17255 SD MET J 15 53.343 39.132 12.297 1.00102.14 S +ATOM 17256 CE MET J 15 54.859 38.205 11.911 1.00123.00 C +ATOM 17257 N PRO J 16 54.546 41.681 8.170 1.00 93.48 N +ATOM 17258 CA PRO J 16 55.741 42.503 7.918 1.00105.76 C +ATOM 17259 C PRO J 16 56.966 42.228 8.797 1.00106.64 C +ATOM 17260 O PRO J 16 57.209 42.917 9.799 1.00139.40 O +ATOM 17261 CB PRO J 16 55.230 43.932 8.145 1.00120.26 C +ATOM 17262 CG PRO J 16 54.060 43.782 9.050 1.00108.45 C +ATOM 17263 CD PRO J 16 53.409 42.507 8.622 1.00 92.73 C +ATOM 17264 N ARG J 17 57.700 41.187 8.449 1.00107.65 N +ATOM 17265 CA ARG J 17 58.934 40.864 9.142 1.00128.97 C +ATOM 17266 C ARG J 17 60.061 41.652 8.475 1.00109.55 C +ATOM 17267 O ARG J 17 60.044 41.805 7.272 1.00108.93 O +ATOM 17268 CB ARG J 17 59.175 39.335 9.098 1.00143.38 C +ATOM 17269 CG ARG J 17 58.513 38.568 10.245 1.00123.21 C +ATOM 17270 CD ARG J 17 58.392 37.085 9.980 1.00117.69 C +ATOM 17271 NE ARG J 17 57.280 36.781 9.093 1.00118.55 N +ATOM 17272 CZ ARG J 17 57.055 35.576 8.579 1.00143.58 C +ATOM 17273 NH1 ARG J 17 57.856 34.556 8.897 1.00160.91 N +ATOM 17274 NH2 ARG J 17 56.035 35.372 7.759 1.00128.72 N +ATOM 17275 N ALA J 18 61.076 42.057 9.236 1.00107.78 N +ATOM 17276 CA ALA J 18 62.195 42.813 8.671 1.00 94.97 C +ATOM 17277 C ALA J 18 63.538 42.041 8.704 1.00 94.51 C +ATOM 17278 O ALA J 18 63.693 41.019 8.024 1.00 71.48 O +ATOM 17279 CB ALA J 18 62.320 44.151 9.365 1.00 88.14 C +ATOM 17280 N GLN J 19 64.531 42.589 9.400 1.00 91.02 N +ATOM 17281 CA GLN J 19 65.926 42.240 9.133 1.00114.86 C +ATOM 17282 C GLN J 19 66.226 40.804 9.574 1.00109.00 C +ATOM 17283 O GLN J 19 66.860 40.021 8.847 1.00108.44 O +ATOM 17284 CB GLN J 19 66.869 43.232 9.841 1.00129.52 C +ATOM 17285 CG GLN J 19 68.353 43.043 9.525 1.00137.81 C +ATOM 17286 CD GLN J 19 68.633 43.064 8.034 1.00125.98 C +ATOM 17287 OE1 GLN J 19 68.482 44.095 7.378 1.00134.86 O +ATOM 17288 NE2 GLN J 19 69.033 41.921 7.489 1.00113.45 N +ATOM 17289 N SER J 20 65.851 40.518 10.815 1.00 86.65 N +ATOM 17290 CA SER J 20 66.001 39.211 11.389 1.00 80.26 C +ATOM 17291 C SER J 20 65.556 38.172 10.363 1.00114.59 C +ATOM 17292 O SER J 20 66.240 37.160 10.142 1.00 99.68 O +ATOM 17293 CB SER J 20 65.154 39.145 12.661 1.00 81.83 C +ATOM 17294 OG SER J 20 65.464 40.218 13.543 1.00 68.50 O +ATOM 17295 N TYR J 21 64.380 38.400 9.772 1.00141.89 N +ATOM 17296 CA TYR J 21 63.800 37.471 8.784 1.00151.30 C +ATOM 17297 C TYR J 21 64.732 37.274 7.599 1.00122.91 C +ATOM 17298 O TYR J 21 64.977 36.140 7.166 1.00 69.14 O +ATOM 17299 CB TYR J 21 62.439 37.997 8.298 1.00163.91 C +ATOM 17300 CG TYR J 21 61.762 37.099 7.280 1.00163.06 C +ATOM 17301 CD1 TYR J 21 61.136 35.920 7.670 1.00173.91 C +ATOM 17302 CD2 TYR J 21 61.752 37.430 5.937 1.00170.18 C +ATOM 17303 CE1 TYR J 21 60.531 35.089 6.753 1.00173.01 C +ATOM 17304 CE2 TYR J 21 61.134 36.602 5.014 1.00182.32 C +ATOM 17305 CZ TYR J 21 60.515 35.437 5.438 1.00174.55 C +ATOM 17306 OH TYR J 21 59.922 34.581 4.542 1.00155.25 O +ATOM 17307 N LYS J 22 65.233 38.391 7.076 1.00124.82 N +ATOM 17308 CA LYS J 22 66.069 38.375 5.883 1.00144.27 C +ATOM 17309 C LYS J 22 67.348 37.582 6.122 1.00148.39 C +ATOM 17310 O LYS J 22 67.799 36.827 5.246 1.00196.21 O +ATOM 17311 CB LYS J 22 66.414 39.806 5.445 1.00123.95 C +ATOM 17312 CG LYS J 22 65.416 40.438 4.483 1.00139.86 C +ATOM 17313 CD LYS J 22 65.889 40.391 3.033 1.00159.14 C +ATOM 17314 CE LYS J 22 64.957 40.340 1.907 1.00172.04 C +ATOM 17315 NZ LYS J 22 65.001 41.600 1.136 1.00153.58 N +ATOM 17316 N ASP J 23 67.921 37.752 7.309 1.00116.44 N +ATOM 17317 CA ASP J 23 69.088 36.970 7.717 1.00128.63 C +ATOM 17318 C ASP J 23 68.738 35.490 7.854 1.00133.87 C +ATOM 17319 O ASP J 23 69.470 34.614 7.380 1.00107.71 O +ATOM 17320 CB ASP J 23 69.619 37.480 9.055 1.00139.47 C +ATOM 17321 CG ASP J 23 70.210 38.854 8.954 1.00134.77 C +ATOM 17322 OD1 ASP J 23 70.919 39.104 7.962 1.00117.40 O +ATOM 17323 OD2 ASP J 23 69.979 39.669 9.875 1.00166.55 O +ATOM 17324 N LEU J 24 67.597 35.229 8.490 1.00144.81 N +ATOM 17325 CA LEU J 24 67.160 33.866 8.807 1.00155.10 C +ATOM 17326 C LEU J 24 66.886 33.033 7.551 1.00163.80 C +ATOM 17327 O LEU J 24 67.149 31.819 7.520 1.00134.34 O +ATOM 17328 CB LEU J 24 65.893 33.922 9.678 1.00150.99 C +ATOM 17329 CG LEU J 24 65.273 32.593 10.143 1.00135.45 C +ATOM 17330 CD1 LEU J 24 65.937 32.096 11.419 1.00146.82 C +ATOM 17331 CD2 LEU J 24 63.781 32.762 10.354 1.00128.76 C +ATOM 17332 N THR J 25 66.332 33.684 6.528 1.00172.44 N +ATOM 17333 CA THR J 25 65.979 33.004 5.281 1.00148.34 C +ATOM 17334 C THR J 25 67.220 32.671 4.439 1.00142.70 C +ATOM 17335 O THR J 25 67.361 31.544 3.943 1.00 86.77 O +ATOM 17336 CB THR J 25 64.991 33.847 4.446 1.00136.69 C +ATOM 17337 OG1 THR J 25 65.447 35.207 4.380 1.00146.80 O +ATOM 17338 CG2 THR J 25 63.605 33.801 5.067 1.00108.76 C +ATOM 17339 N HIS J 26 68.103 33.661 4.276 1.00168.50 N +ATOM 17340 CA HIS J 26 69.295 33.534 3.430 1.00163.78 C +ATOM 17341 C HIS J 26 70.452 32.873 4.205 1.00129.04 C +ATOM 17342 O HIS J 26 71.615 33.212 4.022 1.00124.55 O +ATOM 17343 CB HIS J 26 69.715 34.918 2.878 1.00150.49 C +ATOM 17344 CG HIS J 26 68.704 35.546 1.962 1.00157.09 C +ATOM 17345 ND1 HIS J 26 67.485 36.019 2.402 1.00147.19 N +ATOM 17346 CD2 HIS J 26 68.734 35.777 0.626 1.00173.31 C +ATOM 17347 CE1 HIS J 26 66.797 36.491 1.378 1.00149.44 C +ATOM 17348 NE2 HIS J 26 67.537 36.366 0.290 1.00184.97 N +ATOM 17349 N LEU J 27 70.128 31.921 5.068 1.00106.90 N +ATOM 17350 CA LEU J 27 71.154 31.153 5.759 1.00116.69 C +ATOM 17351 C LEU J 27 71.558 29.954 4.907 1.00 95.11 C +ATOM 17352 O LEU J 27 70.696 29.238 4.394 1.00109.28 O +ATOM 17353 CB LEU J 27 70.649 30.687 7.140 1.00139.34 C +ATOM 17354 CG LEU J 27 70.858 31.678 8.290 1.00133.36 C +ATOM 17355 CD1 LEU J 27 70.055 31.276 9.509 1.00135.07 C +ATOM 17356 CD2 LEU J 27 72.336 31.790 8.646 1.00139.64 C +ATOM 17357 N PRO J 28 72.863 29.683 4.819 1.00 78.29 N +ATOM 17358 CA PRO J 28 73.361 28.528 4.064 1.00 99.07 C +ATOM 17359 C PRO J 28 72.825 27.209 4.581 1.00 96.99 C +ATOM 17360 O PRO J 28 72.905 26.954 5.764 1.00104.74 O +ATOM 17361 CB PRO J 28 74.884 28.590 4.281 1.00124.35 C +ATOM 17362 CG PRO J 28 75.061 29.354 5.546 1.00108.79 C +ATOM 17363 CD PRO J 28 73.939 30.358 5.561 1.00 92.53 C +ATOM 17364 N ALA J 29 72.287 26.374 3.694 1.00139.27 N +ATOM 17365 CA ALA J 29 71.505 25.196 4.109 1.00138.53 C +ATOM 17366 C ALA J 29 72.396 24.056 4.667 1.00114.42 C +ATOM 17367 O ALA J 29 73.563 23.925 4.288 1.00101.51 O +ATOM 17368 CB ALA J 29 70.638 24.694 2.953 1.00129.86 C +ATOM 17369 N PRO J 30 71.859 23.277 5.623 1.00 90.75 N +ATOM 17370 CA PRO J 30 72.569 22.150 6.235 1.00100.62 C +ATOM 17371 C PRO J 30 72.517 20.936 5.331 1.00 89.40 C +ATOM 17372 O PRO J 30 71.847 20.983 4.288 1.00 67.27 O +ATOM 17373 CB PRO J 30 71.755 21.870 7.489 1.00119.88 C +ATOM 17374 CG PRO J 30 70.372 22.317 7.148 1.00116.53 C +ATOM 17375 CD PRO J 30 70.518 23.471 6.202 1.00 99.70 C +ATOM 17376 N THR J 31 73.192 19.858 5.735 1.00 89.63 N +ATOM 17377 CA THR J 31 73.247 18.635 4.914 1.00127.72 C +ATOM 17378 C THR J 31 71.884 17.946 4.814 1.00146.80 C +ATOM 17379 O THR J 31 71.605 17.240 3.838 1.00193.89 O +ATOM 17380 CB THR J 31 74.303 17.610 5.410 1.00115.04 C +ATOM 17381 OG1 THR J 31 74.115 17.334 6.799 1.00131.63 O +ATOM 17382 CG2 THR J 31 75.713 18.135 5.188 1.00131.52 C +ATOM 17383 N GLY J 32 71.055 18.127 5.835 1.00140.12 N +ATOM 17384 CA GLY J 32 69.650 17.726 5.777 1.00149.56 C +ATOM 17385 C GLY J 32 68.876 18.518 6.802 1.00134.45 C +ATOM 17386 O GLY J 32 69.476 19.045 7.741 1.00175.61 O +ATOM 17387 N LYS J 33 67.579 18.716 6.580 1.00114.78 N +ATOM 17388 CA LYS J 33 66.789 19.470 7.551 1.00106.52 C +ATOM 17389 C LYS J 33 66.641 18.658 8.840 1.00124.96 C +ATOM 17390 O LYS J 33 66.711 17.423 8.795 1.00101.46 O +ATOM 17391 CB LYS J 33 65.425 19.841 7.002 1.00 92.88 C +ATOM 17392 CG LYS J 33 65.365 21.187 6.309 1.00 78.32 C +ATOM 17393 CD LYS J 33 64.005 21.399 5.658 1.00 90.35 C +ATOM 17394 CE LYS J 33 64.097 22.359 4.493 1.00104.57 C +ATOM 17395 NZ LYS J 33 62.819 22.454 3.744 1.00 97.89 N +ATOM 17396 N ILE J 34 66.498 19.348 9.979 1.00127.03 N +ATOM 17397 CA ILE J 34 66.461 18.682 11.275 1.00126.34 C +ATOM 17398 C ILE J 34 65.019 18.735 11.789 1.00131.29 C +ATOM 17399 O ILE J 34 64.285 19.671 11.480 1.00 86.57 O +ATOM 17400 CB ILE J 34 67.491 19.290 12.263 1.00132.89 C +ATOM 17401 CG1 ILE J 34 68.920 19.004 11.786 1.00133.40 C +ATOM 17402 CG2 ILE J 34 67.363 18.700 13.659 1.00144.90 C +ATOM 17403 CD1 ILE J 34 69.708 20.261 11.476 1.00145.76 C +ATOM 17404 N PHE J 35 64.586 17.624 12.405 1.00141.71 N +ATOM 17405 CA PHE J 35 63.214 17.440 12.926 1.00 86.38 C +ATOM 17406 C PHE J 35 63.079 18.047 14.305 1.00 73.15 C +ATOM 17407 O PHE J 35 63.901 17.725 15.197 1.00 72.52 O +ATOM 17408 CB PHE J 35 62.929 15.963 13.079 1.00 72.23 C +ATOM 17409 CG PHE J 35 62.390 15.312 11.867 1.00 70.45 C +ATOM 17410 CD1 PHE J 35 61.407 15.928 11.101 1.00 71.28 C +ATOM 17411 CD2 PHE J 35 62.806 14.031 11.537 1.00 70.91 C +ATOM 17412 CE1 PHE J 35 60.916 15.311 9.971 1.00 87.14 C +ATOM 17413 CE2 PHE J 35 62.309 13.400 10.420 1.00 82.75 C +ATOM 17414 CZ PHE J 35 61.366 14.041 9.629 1.00 99.87 C +ATOM 17415 N VAL J 36 62.116 18.951 14.482 1.00 45.08 N +ATOM 17416 CA VAL J 36 62.088 19.706 15.712 1.00 56.54 C +ATOM 17417 C VAL J 36 60.711 19.781 16.280 1.00 66.79 C +ATOM 17418 O VAL J 36 59.728 19.726 15.558 1.00 91.96 O +ATOM 17419 CB VAL J 36 62.601 21.137 15.538 1.00 76.17 C +ATOM 17420 CG1 VAL J 36 61.583 22.008 14.811 1.00 69.24 C +ATOM 17421 CG2 VAL J 36 62.947 21.748 16.896 1.00102.40 C +ATOM 17422 N SER J 37 60.629 19.867 17.605 1.00 75.12 N +ATOM 17423 CA SER J 37 59.342 19.916 18.281 1.00 74.07 C +ATOM 17424 C SER J 37 59.289 21.185 19.077 1.00 61.50 C +ATOM 17425 O SER J 37 60.181 21.436 19.881 1.00 44.85 O +ATOM 17426 CB SER J 37 59.190 18.704 19.218 1.00 83.89 C +ATOM 17427 OG SER J 37 58.930 17.494 18.510 1.00 64.84 O +ATOM 17428 N VAL J 38 58.200 21.924 18.956 1.00 60.27 N +ATOM 17429 CA VAL J 38 57.934 22.948 19.956 1.00 96.59 C +ATOM 17430 C VAL J 38 56.600 22.673 20.656 1.00109.42 C +ATOM 17431 O VAL J 38 55.551 22.693 20.011 1.00105.50 O +ATOM 17432 CB VAL J 38 57.875 24.347 19.334 1.00108.61 C +ATOM 17433 CG1 VAL J 38 57.555 25.394 20.391 1.00124.00 C +ATOM 17434 CG2 VAL J 38 59.186 24.688 18.640 1.00110.64 C +ATOM 17435 N TYR J 39 56.646 22.496 21.988 1.00 97.07 N +ATOM 17436 CA TYR J 39 55.449 22.246 22.792 1.00 77.39 C +ATOM 17437 C TYR J 39 54.814 23.582 23.278 1.00 77.51 C +ATOM 17438 O TYR J 39 53.639 23.842 23.049 1.00 56.78 O +ATOM 17439 CB TYR J 39 55.792 21.299 23.957 1.00 77.81 C +ATOM 17440 CG TYR J 39 55.774 19.803 23.582 1.00 76.13 C +ATOM 17441 CD1 TYR J 39 56.825 19.212 22.907 1.00 49.17 C +ATOM 17442 CD2 TYR J 39 54.675 18.989 23.931 1.00104.53 C +ATOM 17443 CE1 TYR J 39 56.794 17.866 22.594 1.00 41.65 C +ATOM 17444 CE2 TYR J 39 54.614 17.641 23.582 1.00 74.66 C +ATOM 17445 CZ TYR J 39 55.687 17.094 22.918 1.00 52.70 C +ATOM 17446 OH TYR J 39 55.578 15.791 22.532 1.00 57.27 O +ATOM 17447 N ASN J 40 55.607 24.442 23.905 1.00 79.22 N +ATOM 17448 CA ASN J 40 55.090 25.708 24.409 1.00 74.78 C +ATOM 17449 C ASN J 40 56.172 26.700 24.870 1.00 87.49 C +ATOM 17450 O ASN J 40 57.122 26.343 25.581 1.00 84.01 O +ATOM 17451 CB ASN J 40 54.177 25.447 25.583 1.00 93.95 C +ATOM 17452 CG ASN J 40 53.265 26.617 25.868 1.00118.03 C +ATOM 17453 OD1 ASN J 40 52.467 27.031 25.027 1.00140.98 O +ATOM 17454 ND2 ASN J 40 53.361 27.138 27.083 1.00144.98 N +ATOM 17455 N ILE J 41 56.024 27.950 24.451 1.00 83.34 N +ATOM 17456 CA ILE J 41 56.850 29.038 24.963 1.00 75.64 C +ATOM 17457 C ILE J 41 55.943 30.034 25.679 1.00 88.24 C +ATOM 17458 O ILE J 41 55.079 30.653 25.048 1.00126.04 O +ATOM 17459 CB ILE J 41 57.627 29.757 23.835 1.00 66.00 C +ATOM 17460 CG1 ILE J 41 58.895 28.977 23.462 1.00 69.36 C +ATOM 17461 CG2 ILE J 41 58.089 31.123 24.304 1.00 70.39 C +ATOM 17462 CD1 ILE J 41 58.675 27.684 22.721 1.00 70.99 C +ATOM 17463 N GLN J 42 56.142 30.197 26.988 1.00 96.56 N +ATOM 17464 CA GLN J 42 55.192 30.944 27.837 1.00 87.65 C +ATOM 17465 C GLN J 42 55.506 32.411 27.954 1.00 74.37 C +ATOM 17466 O GLN J 42 56.639 32.843 27.707 1.00111.94 O +ATOM 17467 CB GLN J 42 55.165 30.394 29.254 1.00 92.19 C +ATOM 17468 CG GLN J 42 54.644 28.973 29.358 1.00112.68 C +ATOM 17469 CD GLN J 42 55.680 28.020 29.927 1.00120.80 C +ATOM 17470 OE1 GLN J 42 55.797 27.874 31.145 1.00152.77 O +ATOM 17471 NE2 GLN J 42 56.468 27.401 29.050 1.00112.17 N +ATOM 17472 N ASP J 43 54.475 33.185 28.259 1.00 59.71 N +ATOM 17473 CA ASP J 43 54.633 34.611 28.548 1.00 65.31 C +ATOM 17474 C ASP J 43 55.101 34.822 29.966 1.00 52.53 C +ATOM 17475 O ASP J 43 54.312 35.269 30.809 1.00 59.06 O +ATOM 17476 CB ASP J 43 53.285 35.343 28.318 1.00 87.86 C +ATOM 17477 CG ASP J 43 53.409 36.879 28.419 1.00 97.73 C +ATOM 17478 OD1 ASP J 43 54.337 37.443 27.803 1.00112.65 O +ATOM 17479 OD2 ASP J 43 52.622 37.523 29.149 1.00 75.26 O +ATOM 17480 N GLU J 44 56.306 34.361 30.273 1.00 56.06 N +ATOM 17481 CA GLU J 44 56.792 34.312 31.668 1.00 74.15 C +ATOM 17482 C GLU J 44 57.079 35.735 32.176 1.00 80.07 C +ATOM 17483 O GLU J 44 57.752 35.919 33.206 1.00 66.66 O +ATOM 17484 CB GLU J 44 58.049 33.404 31.788 1.00 83.80 C +ATOM 17485 CG GLU J 44 57.784 31.920 32.083 1.00 98.05 C +ATOM 17486 CD GLU J 44 59.063 31.043 32.152 1.00127.73 C +ATOM 17487 OE1 GLU J 44 60.092 31.430 32.779 1.00 94.48 O +ATOM 17488 OE2 GLU J 44 59.034 29.910 31.605 1.00156.60 O +ATOM 17489 N THR J 45 56.554 36.731 31.451 1.00 91.00 N +ATOM 17490 CA THR J 45 56.911 38.142 31.671 1.00104.48 C +ATOM 17491 C THR J 45 56.253 38.764 32.890 1.00 94.51 C +ATOM 17492 O THR J 45 56.892 39.476 33.651 1.00129.09 O +ATOM 17493 CB THR J 45 56.628 39.018 30.440 1.00102.65 C +ATOM 17494 OG1 THR J 45 57.263 40.276 30.597 1.00154.62 O +ATOM 17495 CG2 THR J 45 55.143 39.267 30.233 1.00 91.51 C +ATOM 17496 N GLY J 46 54.985 38.461 33.112 1.00 97.34 N +ATOM 17497 CA GLY J 46 54.299 38.840 34.368 1.00102.50 C +ATOM 17498 C GLY J 46 53.655 40.214 34.276 1.00 85.39 C +ATOM 17499 O GLY J 46 53.289 40.847 35.286 1.00 83.34 O +ATOM 17500 N GLN J 47 53.388 40.641 33.064 1.00 78.16 N +ATOM 17501 CA GLN J 47 53.138 42.016 32.897 1.00 75.20 C +ATOM 17502 C GLN J 47 51.892 42.285 32.072 1.00 64.68 C +ATOM 17503 O GLN J 47 51.616 41.581 31.093 1.00 69.33 O +ATOM 17504 CB GLN J 47 54.362 42.606 32.308 1.00 64.50 C +ATOM 17505 CG GLN J 47 55.541 42.619 33.258 1.00 73.02 C +ATOM 17506 CD GLN J 47 55.201 43.206 34.616 1.00 97.06 C +ATOM 17507 OE1 GLN J 47 54.980 44.404 34.759 1.00 78.42 O +ATOM 17508 NE2 GLN J 47 55.157 42.365 35.624 1.00153.87 N +ATOM 17509 N PHE J 48 51.120 43.255 32.540 1.00 50.31 N +ATOM 17510 CA PHE J 48 49.925 43.693 31.873 1.00 70.64 C +ATOM 17511 C PHE J 48 49.978 45.170 31.550 1.00 90.27 C +ATOM 17512 O PHE J 48 50.813 45.907 32.075 1.00146.80 O +ATOM 17513 CB PHE J 48 48.696 43.432 32.750 1.00 78.46 C +ATOM 17514 CG PHE J 48 48.423 41.988 32.955 1.00 61.92 C +ATOM 17515 CD1 PHE J 48 49.251 41.258 33.717 1.00 46.48 C +ATOM 17516 CD2 PHE J 48 47.385 41.370 32.269 1.00 64.80 C +ATOM 17517 CE1 PHE J 48 49.083 39.922 33.829 1.00 57.32 C +ATOM 17518 CE2 PHE J 48 47.180 40.051 32.417 1.00 63.33 C +ATOM 17519 CZ PHE J 48 48.045 39.318 33.187 1.00 73.40 C +ATOM 17520 N LYS J 49 49.052 45.603 30.700 1.00 96.42 N +ATOM 17521 CA LYS J 49 49.027 46.975 30.253 1.00108.20 C +ATOM 17522 C LYS J 49 48.438 47.835 31.360 1.00 88.62 C +ATOM 17523 O LYS J 49 47.510 47.408 32.056 1.00 69.61 O +ATOM 17524 CB LYS J 49 48.249 47.109 28.916 1.00126.59 C +ATOM 17525 CG LYS J 49 48.957 46.395 27.765 1.00112.50 C +ATOM 17526 CD LYS J 49 48.404 46.638 26.374 1.00102.74 C +ATOM 17527 CE LYS J 49 49.375 45.978 25.396 1.00120.32 C +ATOM 17528 NZ LYS J 49 49.050 46.135 23.947 1.00160.35 N +ATOM 17529 N PRO J 50 48.969 49.058 31.502 1.00 70.87 N +ATOM 17530 CA PRO J 50 48.392 50.059 32.382 1.00 77.10 C +ATOM 17531 C PRO J 50 47.078 50.700 31.903 1.00 91.78 C +ATOM 17532 O PRO J 50 46.685 50.573 30.734 1.00 98.76 O +ATOM 17533 CB PRO J 50 49.500 51.114 32.461 1.00 75.29 C +ATOM 17534 CG PRO J 50 50.182 51.033 31.151 1.00 65.40 C +ATOM 17535 CD PRO J 50 50.086 49.598 30.706 1.00 58.20 C +ATOM 17536 N TYR J 51 46.414 51.425 32.799 1.00101.93 N +ATOM 17537 CA TYR J 51 45.273 52.252 32.392 1.00105.43 C +ATOM 17538 C TYR J 51 45.653 53.090 31.169 1.00100.28 C +ATOM 17539 O TYR J 51 46.750 53.683 31.163 1.00148.42 O +ATOM 17540 CB TYR J 51 44.831 53.172 33.536 1.00 89.43 C +ATOM 17541 CG TYR J 51 43.481 53.769 33.267 1.00 75.12 C +ATOM 17542 CD1 TYR J 51 42.344 53.092 33.625 1.00 80.57 C +ATOM 17543 CD2 TYR J 51 43.340 55.008 32.652 1.00 97.45 C +ATOM 17544 CE1 TYR J 51 41.088 53.607 33.362 1.00103.12 C +ATOM 17545 CE2 TYR J 51 42.077 55.557 32.411 1.00108.54 C +ATOM 17546 CZ TYR J 51 40.956 54.824 32.744 1.00105.89 C +ATOM 17547 OH TYR J 51 39.679 55.297 32.543 1.00119.19 O +ATOM 17548 N PRO J 52 44.776 53.158 30.141 1.00 73.04 N +ATOM 17549 CA PRO J 52 43.384 52.742 30.102 1.00 92.02 C +ATOM 17550 C PRO J 52 43.135 51.388 29.493 1.00130.91 C +ATOM 17551 O PRO J 52 41.980 51.087 29.150 1.00156.62 O +ATOM 17552 CB PRO J 52 42.738 53.784 29.198 1.00 97.43 C +ATOM 17553 CG PRO J 52 43.818 54.113 28.225 1.00 99.53 C +ATOM 17554 CD PRO J 52 45.107 54.023 28.998 1.00 83.79 C +ATOM 17555 N ALA J 53 44.161 50.542 29.418 1.00143.87 N +ATOM 17556 CA ALA J 53 43.946 49.190 28.914 1.00150.94 C +ATOM 17557 C ALA J 53 42.995 48.394 29.822 1.00115.24 C +ATOM 17558 O ALA J 53 42.830 48.724 31.018 1.00 85.82 O +ATOM 17559 CB ALA J 53 45.274 48.466 28.756 1.00145.42 C +ATOM 17560 N SER J 54 42.382 47.353 29.260 1.00 83.02 N +ATOM 17561 CA SER J 54 41.729 46.378 30.108 1.00 74.86 C +ATOM 17562 C SER J 54 42.725 45.763 31.084 1.00 76.32 C +ATOM 17563 O SER J 54 43.926 45.577 30.808 1.00 58.61 O +ATOM 17564 CB SER J 54 41.098 45.258 29.323 1.00 77.78 C +ATOM 17565 OG SER J 54 40.882 44.100 30.134 1.00 71.16 O +ATOM 17566 N ASN J 55 42.232 45.545 32.296 1.00 72.14 N +ATOM 17567 CA ASN J 55 43.047 44.991 33.364 1.00 64.01 C +ATOM 17568 C ASN J 55 43.751 43.750 32.886 1.00 61.67 C +ATOM 17569 O ASN J 55 44.852 43.378 33.374 1.00 65.72 O +ATOM 17570 CB ASN J 55 42.143 44.670 34.536 1.00 70.58 C +ATOM 17571 CG ASN J 55 42.910 44.372 35.789 1.00109.26 C +ATOM 17572 OD1 ASN J 55 44.056 44.783 35.970 1.00187.36 O +ATOM 17573 ND2 ASN J 55 42.241 43.737 36.704 1.00128.68 N +ATOM 17574 N PHE J 56 43.096 43.092 31.931 1.00 79.38 N +ATOM 17575 CA PHE J 56 43.469 41.734 31.513 1.00100.80 C +ATOM 17576 C PHE J 56 44.333 41.756 30.287 1.00 98.62 C +ATOM 17577 O PHE J 56 44.696 40.689 29.780 1.00111.81 O +ATOM 17578 CB PHE J 56 42.237 40.863 31.166 1.00 76.62 C +ATOM 17579 CG PHE J 56 41.291 40.678 32.293 1.00 58.54 C +ATOM 17580 CD1 PHE J 56 41.705 40.114 33.489 1.00 47.01 C +ATOM 17581 CD2 PHE J 56 40.036 41.193 32.203 1.00 64.40 C +ATOM 17582 CE1 PHE J 56 40.872 40.083 34.572 1.00 50.21 C +ATOM 17583 CE2 PHE J 56 39.167 41.112 33.269 1.00 77.24 C +ATOM 17584 CZ PHE J 56 39.592 40.563 34.464 1.00 69.04 C +ATOM 17585 N SER J 57 44.600 42.934 29.747 1.00 76.76 N +ATOM 17586 CA SER J 57 45.410 42.975 28.555 1.00 87.85 C +ATOM 17587 C SER J 57 46.874 42.716 28.943 1.00 59.62 C +ATOM 17588 O SER J 57 47.508 43.521 29.632 1.00 73.67 O +ATOM 17589 CB SER J 57 45.213 44.302 27.810 1.00120.31 C +ATOM 17590 OG SER J 57 43.947 44.320 27.138 1.00 94.17 O +ATOM 17591 N THR J 58 47.406 41.598 28.482 1.00 44.53 N +ATOM 17592 CA THR J 58 48.796 41.318 28.678 1.00 63.28 C +ATOM 17593 C THR J 58 49.718 42.269 27.925 1.00 73.10 C +ATOM 17594 O THR J 58 49.419 42.765 26.866 1.00 62.93 O +ATOM 17595 CB THR J 58 49.118 39.919 28.202 1.00 69.00 C +ATOM 17596 OG1 THR J 58 48.881 39.831 26.804 1.00 65.18 O +ATOM 17597 CG2 THR J 58 48.218 38.948 28.891 1.00 76.22 C +ATOM 17598 N ALA J 59 50.898 42.457 28.451 1.00 92.57 N +ATOM 17599 CA ALA J 59 51.779 43.379 27.797 1.00 89.11 C +ATOM 17600 C ALA J 59 52.387 42.752 26.567 1.00 61.29 C +ATOM 17601 O ALA J 59 52.882 43.469 25.694 1.00 83.20 O +ATOM 17602 CB ALA J 59 52.860 43.842 28.740 1.00112.35 C +ATOM 17603 N VAL J 60 52.316 41.440 26.472 1.00 45.17 N +ATOM 17604 CA VAL J 60 52.997 40.739 25.427 1.00 61.82 C +ATOM 17605 C VAL J 60 52.022 39.727 24.868 1.00 78.50 C +ATOM 17606 O VAL J 60 51.344 39.043 25.619 1.00116.43 O +ATOM 17607 CB VAL J 60 54.254 40.021 25.982 1.00 68.23 C +ATOM 17608 CG1 VAL J 60 54.987 39.204 24.905 1.00 56.27 C +ATOM 17609 CG2 VAL J 60 55.210 41.044 26.617 1.00 77.11 C +ATOM 17610 N PRO J 61 52.038 39.522 23.548 1.00 83.63 N +ATOM 17611 CA PRO J 61 51.149 38.513 22.980 1.00 99.10 C +ATOM 17612 C PRO J 61 51.506 37.088 23.388 1.00107.15 C +ATOM 17613 O PRO J 61 52.700 36.759 23.566 1.00102.45 O +ATOM 17614 CB PRO J 61 51.334 38.683 21.473 1.00105.83 C +ATOM 17615 CG PRO J 61 52.661 39.336 21.322 1.00 92.79 C +ATOM 17616 CD PRO J 61 52.791 40.232 22.510 1.00 87.73 C +ATOM 17617 N GLN J 62 50.472 36.263 23.543 1.00 81.89 N +ATOM 17618 CA GLN J 62 50.647 34.919 24.087 1.00108.68 C +ATOM 17619 C GLN J 62 50.938 33.938 22.987 1.00 85.42 C +ATOM 17620 O GLN J 62 50.479 32.806 23.036 1.00117.14 O +ATOM 17621 CB GLN J 62 49.376 34.469 24.846 1.00132.47 C +ATOM 17622 CG GLN J 62 48.873 35.455 25.895 1.00127.01 C +ATOM 17623 CD GLN J 62 49.908 35.753 26.966 1.00102.18 C +ATOM 17624 OE1 GLN J 62 50.147 34.945 27.853 1.00103.41 O +ATOM 17625 NE2 GLN J 62 50.578 36.877 26.832 1.00 93.43 N +ATOM 17626 N SER J 63 51.688 34.370 21.999 1.00 68.38 N +ATOM 17627 CA SER J 63 51.682 33.698 20.722 1.00 93.98 C +ATOM 17628 C SER J 63 53.078 33.252 20.329 1.00 97.04 C +ATOM 17629 O SER J 63 53.315 32.829 19.190 1.00110.85 O +ATOM 17630 CB SER J 63 51.064 34.623 19.639 1.00139.58 C +ATOM 17631 OG SER J 63 51.776 35.836 19.436 1.00118.75 O +ATOM 17632 N ALA J 64 54.004 33.395 21.267 1.00 85.35 N +ATOM 17633 CA ALA J 64 55.415 33.167 21.004 1.00100.06 C +ATOM 17634 C ALA J 64 55.712 31.780 20.404 1.00111.66 C +ATOM 17635 O ALA J 64 56.552 31.627 19.498 1.00 95.99 O +ATOM 17636 CB ALA J 64 56.187 33.350 22.288 1.00 95.91 C +ATOM 17637 N THR J 65 54.978 30.785 20.882 1.00119.51 N +ATOM 17638 CA THR J 65 55.133 29.414 20.432 1.00119.62 C +ATOM 17639 C THR J 65 55.036 29.308 18.919 1.00128.35 C +ATOM 17640 O THR J 65 55.876 28.676 18.274 1.00 97.02 O +ATOM 17641 CB THR J 65 54.019 28.548 21.034 1.00127.86 C +ATOM 17642 OG1 THR J 65 53.791 28.964 22.383 1.00147.24 O +ATOM 17643 CG2 THR J 65 54.397 27.061 20.991 1.00128.35 C +ATOM 17644 N ALA J 66 53.969 29.879 18.362 1.00126.14 N +ATOM 17645 CA ALA J 66 53.712 29.753 16.944 1.00108.76 C +ATOM 17646 C ALA J 66 54.752 30.551 16.138 1.00146.31 C +ATOM 17647 O ALA J 66 55.159 30.131 15.044 1.00186.09 O +ATOM 17648 CB ALA J 66 52.311 30.213 16.642 1.00 94.53 C +ATOM 17649 N MET J 67 55.204 31.679 16.700 1.00156.65 N +ATOM 17650 CA MET J 67 56.245 32.512 16.066 1.00129.36 C +ATOM 17651 C MET J 67 57.564 31.760 15.992 1.00105.21 C +ATOM 17652 O MET J 67 58.230 31.750 14.939 1.00 93.67 O +ATOM 17653 CB MET J 67 56.478 33.806 16.842 1.00112.04 C +ATOM 17654 CG MET J 67 55.345 34.819 16.775 1.00108.60 C +ATOM 17655 SD MET J 67 55.585 36.130 17.986 1.00110.68 S +ATOM 17656 CE MET J 67 54.241 37.249 17.551 1.00101.22 C +ATOM 17657 N LEU J 68 57.883 31.043 17.070 1.00 94.90 N +ATOM 17658 CA LEU J 68 59.082 30.219 17.066 1.00131.73 C +ATOM 17659 C LEU J 68 59.008 29.095 16.028 1.00146.84 C +ATOM 17660 O LEU J 68 59.976 28.850 15.314 1.00116.34 O +ATOM 17661 CB LEU J 68 59.349 29.599 18.436 1.00137.09 C +ATOM 17662 CG LEU J 68 60.504 28.561 18.432 1.00116.04 C +ATOM 17663 CD1 LEU J 68 61.830 29.238 18.122 1.00106.63 C +ATOM 17664 CD2 LEU J 68 60.593 27.787 19.739 1.00 86.68 C +ATOM 17665 N VAL J 69 57.882 28.382 15.980 1.00132.99 N +ATOM 17666 CA VAL J 69 57.727 27.282 15.022 1.00106.98 C +ATOM 17667 C VAL J 69 57.899 27.841 13.614 1.00137.27 C +ATOM 17668 O VAL J 69 58.547 27.238 12.764 1.00161.28 O +ATOM 17669 CB VAL J 69 56.351 26.591 15.136 1.00115.55 C +ATOM 17670 CG1 VAL J 69 56.169 25.596 14.006 1.00109.34 C +ATOM 17671 CG2 VAL J 69 56.192 25.875 16.468 1.00126.39 C +ATOM 17672 N THR J 70 57.279 28.994 13.361 1.00155.18 N +ATOM 17673 CA THR J 70 57.336 29.632 12.043 1.00116.95 C +ATOM 17674 C THR J 70 58.761 30.023 11.701 1.00 85.93 C +ATOM 17675 O THR J 70 59.232 29.776 10.578 1.00 73.63 O +ATOM 17676 CB THR J 70 56.414 30.860 11.985 1.00107.84 C +ATOM 17677 OG1 THR J 70 55.081 30.447 12.335 1.00126.75 O +ATOM 17678 CG2 THR J 70 56.414 31.478 10.583 1.00111.74 C +ATOM 17679 N ALA J 71 59.447 30.627 12.663 1.00 83.26 N +ATOM 17680 CA ALA J 71 60.844 30.993 12.457 1.00105.81 C +ATOM 17681 C ALA J 71 61.711 29.754 12.190 1.00 97.39 C +ATOM 17682 O ALA J 71 62.589 29.767 11.292 1.00 91.74 O +ATOM 17683 CB ALA J 71 61.379 31.760 13.654 1.00111.78 C +ATOM 17684 N LEU J 72 61.457 28.686 12.944 1.00 78.67 N +ATOM 17685 CA LEU J 72 62.185 27.418 12.737 1.00105.57 C +ATOM 17686 C LEU J 72 61.952 26.850 11.336 1.00127.57 C +ATOM 17687 O LEU J 72 62.801 26.141 10.795 1.00 98.63 O +ATOM 17688 CB LEU J 72 61.778 26.365 13.767 1.00 82.76 C +ATOM 17689 CG LEU J 72 62.203 26.672 15.184 1.00 82.96 C +ATOM 17690 CD1 LEU J 72 61.410 25.821 16.133 1.00 78.66 C +ATOM 17691 CD2 LEU J 72 63.688 26.438 15.393 1.00102.18 C +ATOM 17692 N LYS J 73 60.810 27.187 10.737 1.00132.04 N +ATOM 17693 CA LYS J 73 60.505 26.710 9.388 1.00117.27 C +ATOM 17694 C LYS J 73 61.135 27.594 8.332 1.00101.26 C +ATOM 17695 O LYS J 73 61.715 27.088 7.375 1.00102.53 O +ATOM 17696 CB LYS J 73 58.995 26.627 9.147 1.00132.56 C +ATOM 17697 CG LYS J 73 58.614 25.850 7.881 1.00134.23 C +ATOM 17698 CD LYS J 73 57.097 25.795 7.675 1.00134.71 C +ATOM 17699 CE LYS J 73 56.724 25.681 6.202 1.00138.53 C +ATOM 17700 NZ LYS J 73 56.087 24.384 5.852 1.00131.01 N +ATOM 17701 N ASP J 74 60.986 28.908 8.487 1.00 90.51 N +ATOM 17702 CA ASP J 74 61.482 29.861 7.489 1.00 95.17 C +ATOM 17703 C ASP J 74 62.990 29.711 7.289 1.00 94.37 C +ATOM 17704 O ASP J 74 63.507 30.015 6.209 1.00107.14 O +ATOM 17705 CB ASP J 74 61.137 31.309 7.880 1.00 87.17 C +ATOM 17706 CG ASP J 74 59.646 31.630 7.759 1.00 97.44 C +ATOM 17707 OD1 ASP J 74 58.908 30.962 6.983 1.00 67.42 O +ATOM 17708 OD2 ASP J 74 59.184 32.475 8.576 1.00115.72 O +ATOM 17709 N SER J 75 63.690 29.288 8.343 1.00 93.36 N +ATOM 17710 CA SER J 75 65.152 29.179 8.317 1.00120.15 C +ATOM 17711 C SER J 75 65.643 28.152 7.297 1.00118.71 C +ATOM 17712 O SER J 75 66.793 28.217 6.840 1.00120.22 O +ATOM 17713 CB SER J 75 65.697 28.813 9.706 1.00129.32 C +ATOM 17714 OG SER J 75 65.680 27.407 9.911 1.00120.07 O +ATOM 17715 N ARG J 76 64.780 27.194 6.983 1.00116.97 N +ATOM 17716 CA ARG J 76 65.114 26.082 6.099 1.00148.75 C +ATOM 17717 C ARG J 76 66.267 25.261 6.662 1.00133.52 C +ATOM 17718 O ARG J 76 67.069 24.701 5.922 1.00134.65 O +ATOM 17719 CB ARG J 76 65.450 26.571 4.695 1.00166.47 C +ATOM 17720 CG ARG J 76 64.328 27.334 3.993 1.00150.59 C +ATOM 17721 CD ARG J 76 64.763 27.743 2.594 1.00135.38 C +ATOM 17722 NE ARG J 76 65.805 28.772 2.632 1.00164.03 N +ATOM 17723 CZ ARG J 76 67.124 28.547 2.603 1.00162.18 C +ATOM 17724 NH1 ARG J 76 67.619 27.311 2.525 1.00156.45 N +ATOM 17725 NH2 ARG J 76 67.959 29.577 2.668 1.00134.78 N +ATOM 17726 N TRP J 77 66.258 25.113 7.980 1.00131.79 N +ATOM 17727 CA TRP J 77 67.107 24.155 8.676 1.00133.50 C +ATOM 17728 C TRP J 77 66.291 23.038 9.369 1.00147.53 C +ATOM 17729 O TRP J 77 66.746 21.900 9.484 1.00 92.34 O +ATOM 17730 CB TRP J 77 67.921 24.910 9.711 1.00139.03 C +ATOM 17731 CG TRP J 77 69.226 25.380 9.208 1.00124.11 C +ATOM 17732 CD1 TRP J 77 69.455 26.471 8.424 1.00116.51 C +ATOM 17733 CD2 TRP J 77 70.507 24.840 9.539 1.00111.73 C +ATOM 17734 NE1 TRP J 77 70.800 26.644 8.251 1.00130.07 N +ATOM 17735 CE2 TRP J 77 71.467 25.643 8.914 1.00118.05 C +ATOM 17736 CE3 TRP J 77 70.936 23.753 10.309 1.00108.46 C +ATOM 17737 CZ2 TRP J 77 72.828 25.372 8.998 1.00119.59 C +ATOM 17738 CZ3 TRP J 77 72.290 23.496 10.400 1.00101.75 C +ATOM 17739 CH2 TRP J 77 73.216 24.294 9.744 1.00100.63 C +ATOM 17740 N PHE J 78 65.085 23.392 9.824 1.00156.36 N +ATOM 17741 CA PHE J 78 64.236 22.510 10.629 1.00107.30 C +ATOM 17742 C PHE J 78 62.870 22.240 9.996 1.00 92.70 C +ATOM 17743 O PHE J 78 62.266 23.129 9.390 1.00 63.41 O +ATOM 17744 CB PHE J 78 63.973 23.164 11.961 1.00 98.59 C +ATOM 17745 CG PHE J 78 65.208 23.545 12.684 1.00 84.44 C +ATOM 17746 CD1 PHE J 78 66.013 22.564 13.282 1.00 70.48 C +ATOM 17747 CD2 PHE J 78 65.559 24.891 12.789 1.00 66.96 C +ATOM 17748 CE1 PHE J 78 67.123 22.931 14.008 1.00 94.01 C +ATOM 17749 CE2 PHE J 78 66.681 25.261 13.497 1.00 84.17 C +ATOM 17750 CZ PHE J 78 67.474 24.280 14.102 1.00106.00 C +ATOM 17751 N ILE J 79 62.395 21.008 10.160 1.00 95.77 N +ATOM 17752 CA ILE J 79 60.992 20.643 9.935 1.00 96.87 C +ATOM 17753 C ILE J 79 60.311 20.632 11.297 1.00104.59 C +ATOM 17754 O ILE J 79 60.814 19.982 12.225 1.00 77.75 O +ATOM 17755 CB ILE J 79 60.864 19.224 9.362 1.00102.62 C +ATOM 17756 CG1 ILE J 79 61.813 19.034 8.178 1.00133.43 C +ATOM 17757 CG2 ILE J 79 59.427 18.936 8.945 1.00 81.58 C +ATOM 17758 CD1 ILE J 79 62.182 17.585 7.903 1.00127.39 C +ATOM 17759 N PRO J 80 59.248 21.440 11.448 1.00 98.97 N +ATOM 17760 CA PRO J 80 58.622 21.425 12.733 1.00 78.43 C +ATOM 17761 C PRO J 80 57.553 20.380 12.744 1.00 67.73 C +ATOM 17762 O PRO J 80 56.777 20.297 11.817 1.00 44.34 O +ATOM 17763 CB PRO J 80 58.033 22.837 12.865 1.00 68.68 C +ATOM 17764 CG PRO J 80 58.871 23.659 11.979 1.00 97.56 C +ATOM 17765 CD PRO J 80 59.084 22.751 10.800 1.00110.89 C +ATOM 17766 N LEU J 81 57.563 19.558 13.790 1.00 74.09 N +ATOM 17767 CA LEU J 81 56.491 18.624 14.054 1.00 66.66 C +ATOM 17768 C LEU J 81 55.462 19.216 15.003 1.00 84.07 C +ATOM 17769 O LEU J 81 55.805 20.047 15.882 1.00 79.34 O +ATOM 17770 CB LEU J 81 57.050 17.381 14.648 1.00 66.08 C +ATOM 17771 CG LEU J 81 58.173 16.817 13.784 1.00 92.64 C +ATOM 17772 CD1 LEU J 81 58.770 15.631 14.494 1.00 89.17 C +ATOM 17773 CD2 LEU J 81 57.643 16.405 12.429 1.00129.12 C +ATOM 17774 N GLU J 82 54.192 18.966 14.666 1.00104.58 N +ATOM 17775 CA GLU J 82 53.058 19.650 15.314 1.00109.40 C +ATOM 17776 C GLU J 82 52.741 18.999 16.635 1.00113.83 C +ATOM 17777 O GLU J 82 52.302 17.847 16.687 1.00 75.87 O +ATOM 17778 CB GLU J 82 51.801 19.678 14.437 1.00100.81 C +ATOM 17779 CG GLU J 82 50.571 20.309 15.104 1.00 87.41 C +ATOM 17780 CD GLU J 82 50.650 21.840 15.305 1.00 79.58 C +ATOM 17781 OE1 GLU J 82 51.658 22.383 15.782 1.00 94.05 O +ATOM 17782 OE2 GLU J 82 49.681 22.545 14.975 1.00 66.28 O +ATOM 17783 N ARG J 83 53.059 19.739 17.697 1.00128.65 N +ATOM 17784 CA ARG J 83 52.769 19.319 19.057 1.00 94.43 C +ATOM 17785 C ARG J 83 51.894 20.335 19.796 1.00 73.74 C +ATOM 17786 O ARG J 83 51.261 19.986 20.784 1.00 59.63 O +ATOM 17787 CB ARG J 83 54.068 19.045 19.825 1.00 77.07 C +ATOM 17788 CG ARG J 83 54.982 18.029 19.171 1.00 51.63 C +ATOM 17789 CD ARG J 83 54.425 16.668 19.203 1.00 37.92 C +ATOM 17790 NE ARG J 83 55.513 15.802 18.776 1.00 47.89 N +ATOM 17791 CZ ARG J 83 55.582 15.191 17.601 1.00 78.25 C +ATOM 17792 NH1 ARG J 83 54.634 15.365 16.665 1.00 90.91 N +ATOM 17793 NH2 ARG J 83 56.620 14.384 17.337 1.00 88.14 N +ATOM 17794 N GLN J 84 51.832 21.582 19.332 1.00 81.89 N +ATOM 17795 CA GLN J 84 50.984 22.574 20.032 1.00110.77 C +ATOM 17796 C GLN J 84 49.531 22.113 20.029 1.00 97.20 C +ATOM 17797 O GLN J 84 48.856 22.179 21.032 1.00 96.95 O +ATOM 17798 CB GLN J 84 51.103 23.993 19.448 1.00102.33 C +ATOM 17799 CG GLN J 84 50.891 25.114 20.462 1.00 82.05 C +ATOM 17800 CD GLN J 84 50.890 26.485 19.798 1.00 94.01 C +ATOM 17801 OE1 GLN J 84 51.682 26.757 18.890 1.00 76.66 O +ATOM 17802 NE2 GLN J 84 50.067 27.391 20.317 1.00121.52 N +ATOM 17803 N GLY J 85 49.082 21.538 18.937 1.00 87.36 N +ATOM 17804 CA GLY J 85 47.718 21.024 18.922 1.00 92.38 C +ATOM 17805 C GLY J 85 47.621 19.512 18.900 1.00 85.20 C +ATOM 17806 O GLY J 85 46.813 18.961 18.137 1.00 88.00 O +ATOM 17807 N LEU J 86 48.498 18.831 19.646 1.00 66.43 N +ATOM 17808 CA LEU J 86 48.733 17.384 19.426 1.00 70.20 C +ATOM 17809 C LEU J 86 47.463 16.584 19.645 1.00 78.88 C +ATOM 17810 O LEU J 86 47.199 15.600 18.933 1.00 73.73 O +ATOM 17811 CB LEU J 86 49.815 16.850 20.354 1.00 75.38 C +ATOM 17812 CG LEU J 86 50.065 15.326 20.449 1.00 70.26 C +ATOM 17813 CD1 LEU J 86 50.479 14.700 19.143 1.00 58.61 C +ATOM 17814 CD2 LEU J 86 51.149 15.075 21.503 1.00 97.71 C +ATOM 17815 N GLN J 87 46.622 17.077 20.542 1.00 86.02 N +ATOM 17816 CA GLN J 87 45.411 16.361 20.875 1.00105.09 C +ATOM 17817 C GLN J 87 44.480 16.205 19.644 1.00108.85 C +ATOM 17818 O GLN J 87 43.904 15.122 19.395 1.00 86.67 O +ATOM 17819 CB GLN J 87 44.715 17.052 22.056 1.00104.23 C +ATOM 17820 CG GLN J 87 44.012 16.080 22.999 1.00116.42 C +ATOM 17821 CD GLN J 87 44.829 14.815 23.302 1.00109.29 C +ATOM 17822 OE1 GLN J 87 45.955 14.889 23.795 1.00 95.48 O +ATOM 17823 NE2 GLN J 87 44.244 13.650 23.036 1.00105.49 N +ATOM 17824 N ASN J 88 44.327 17.290 18.880 1.00105.21 N +ATOM 17825 CA ASN J 88 43.448 17.288 17.696 1.00 98.40 C +ATOM 17826 C ASN J 88 43.983 16.352 16.635 1.00 86.97 C +ATOM 17827 O ASN J 88 43.245 15.727 15.884 1.00 73.47 O +ATOM 17828 CB ASN J 88 43.363 18.682 17.102 1.00 97.07 C +ATOM 17829 CG ASN J 88 42.860 19.684 18.077 1.00109.98 C +ATOM 17830 OD1 ASN J 88 41.982 19.372 18.890 1.00163.62 O +ATOM 17831 ND2 ASN J 88 43.428 20.891 18.048 1.00120.26 N +ATOM 17832 N LEU J 89 45.299 16.282 16.571 1.00 90.81 N +ATOM 17833 CA LEU J 89 45.967 15.495 15.565 1.00 92.03 C +ATOM 17834 C LEU J 89 45.622 14.042 15.861 1.00 77.73 C +ATOM 17835 O LEU J 89 45.326 13.257 14.941 1.00103.14 O +ATOM 17836 CB LEU J 89 47.486 15.785 15.634 1.00120.73 C +ATOM 17837 CG LEU J 89 48.350 15.658 14.383 1.00103.44 C +ATOM 17838 CD1 LEU J 89 49.341 14.528 14.572 1.00113.23 C +ATOM 17839 CD2 LEU J 89 47.503 15.412 13.150 1.00102.80 C +ATOM 17840 N LEU J 90 45.650 13.693 17.146 1.00 63.72 N +ATOM 17841 CA LEU J 90 45.447 12.293 17.542 1.00 67.91 C +ATOM 17842 C LEU J 90 43.980 11.915 17.348 1.00 80.65 C +ATOM 17843 O LEU J 90 43.643 10.771 17.060 1.00 82.12 O +ATOM 17844 CB LEU J 90 45.858 12.098 18.981 1.00 52.44 C +ATOM 17845 CG LEU J 90 47.312 12.385 19.274 1.00 55.93 C +ATOM 17846 CD1 LEU J 90 47.524 12.612 20.754 1.00 64.56 C +ATOM 17847 CD2 LEU J 90 48.137 11.211 18.783 1.00 71.24 C +ATOM 17848 N ASN J 91 43.113 12.911 17.486 1.00 83.17 N +ATOM 17849 CA ASN J 91 41.683 12.724 17.291 1.00 69.27 C +ATOM 17850 C ASN J 91 41.351 12.456 15.828 1.00 61.01 C +ATOM 17851 O ASN J 91 40.642 11.522 15.512 1.00 66.38 O +ATOM 17852 CB ASN J 91 40.967 13.987 17.773 1.00 94.47 C +ATOM 17853 CG ASN J 91 40.066 13.776 18.956 1.00109.13 C +ATOM 17854 OD1 ASN J 91 40.196 12.823 19.721 1.00121.30 O +ATOM 17855 ND2 ASN J 91 39.149 14.716 19.126 1.00136.54 N +ATOM 17856 N GLU J 92 41.878 13.276 14.922 1.00 68.89 N +ATOM 17857 CA GLU J 92 41.694 13.039 13.472 1.00 65.70 C +ATOM 17858 C GLU J 92 42.215 11.665 13.058 1.00 65.75 C +ATOM 17859 O GLU J 92 41.618 10.987 12.219 1.00 75.60 O +ATOM 17860 CB GLU J 92 42.384 14.110 12.609 1.00 57.08 C +ATOM 17861 CG GLU J 92 41.522 15.323 12.263 1.00 47.89 C +ATOM 17862 CD GLU J 92 40.188 15.001 11.624 1.00 43.27 C +ATOM 17863 OE1 GLU J 92 40.150 14.283 10.586 1.00 71.24 O +ATOM 17864 OE2 GLU J 92 39.146 15.358 12.230 1.00 38.06 O +ATOM 17865 N ARG J 93 43.293 11.233 13.698 1.00 65.01 N +ATOM 17866 CA ARG J 93 43.843 9.911 13.438 1.00 74.78 C +ATOM 17867 C ARG J 93 42.948 8.786 14.001 1.00 74.23 C +ATOM 17868 O ARG J 93 42.774 7.747 13.374 1.00 52.53 O +ATOM 17869 CB ARG J 93 45.279 9.835 13.967 1.00 74.71 C +ATOM 17870 CG ARG J 93 46.246 10.720 13.164 1.00 77.96 C +ATOM 17871 CD ARG J 93 47.609 10.988 13.835 1.00 56.93 C +ATOM 17872 NE ARG J 93 48.715 10.207 13.292 1.00 47.62 N +ATOM 17873 CZ ARG J 93 49.057 9.016 13.744 1.00 57.65 C +ATOM 17874 NH1 ARG J 93 48.480 8.481 14.845 1.00 97.68 N +ATOM 17875 NH2 ARG J 93 50.044 8.383 13.180 1.00 51.86 N +ATOM 17876 N LYS J 94 42.266 9.051 15.108 1.00 92.56 N +ATOM 17877 CA LYS J 94 41.233 8.122 15.579 1.00105.29 C +ATOM 17878 C LYS J 94 40.109 7.985 14.540 1.00 90.29 C +ATOM 17879 O LYS J 94 39.583 6.893 14.331 1.00 66.69 O +ATOM 17880 CB LYS J 94 40.640 8.595 16.913 1.00118.59 C +ATOM 17881 CG LYS J 94 41.391 8.142 18.154 1.00128.53 C +ATOM 17882 CD LYS J 94 40.833 8.835 19.388 1.00135.51 C +ATOM 17883 CE LYS J 94 41.174 8.109 20.682 1.00138.91 C +ATOM 17884 NZ LYS J 94 40.918 8.993 21.851 1.00150.50 N +ATOM 17885 N ILE J 95 39.702 9.116 13.960 1.00 79.27 N +ATOM 17886 CA ILE J 95 38.544 9.134 13.083 1.00 82.76 C +ATOM 17887 C ILE J 95 38.881 8.426 11.803 1.00 90.42 C +ATOM 17888 O ILE J 95 38.026 7.701 11.233 1.00128.44 O +ATOM 17889 CB ILE J 95 38.036 10.555 12.744 1.00 86.20 C +ATOM 17890 CG1 ILE J 95 37.867 11.400 14.022 1.00 78.98 C +ATOM 17891 CG2 ILE J 95 36.686 10.422 12.050 1.00 82.28 C +ATOM 17892 CD1 ILE J 95 37.070 12.671 13.847 1.00 75.33 C +ATOM 17893 N ILE J 96 40.102 8.683 11.332 1.00 76.92 N +ATOM 17894 CA ILE J 96 40.643 7.959 10.205 1.00 84.95 C +ATOM 17895 C ILE J 96 40.577 6.460 10.472 1.00 83.36 C +ATOM 17896 O ILE J 96 39.969 5.714 9.696 1.00122.95 O +ATOM 17897 CB ILE J 96 42.093 8.349 9.887 1.00 88.40 C +ATOM 17898 CG1 ILE J 96 42.148 9.789 9.400 1.00100.69 C +ATOM 17899 CG2 ILE J 96 42.656 7.453 8.791 1.00 82.72 C +ATOM 17900 CD1 ILE J 96 43.546 10.231 9.010 1.00121.40 C +ATOM 17901 N ARG J 97 41.238 6.016 11.526 1.00 77.66 N +ATOM 17902 CA ARG J 97 41.345 4.585 11.793 1.00 90.96 C +ATOM 17903 C ARG J 97 39.956 3.962 11.933 1.00 93.88 C +ATOM 17904 O ARG J 97 39.763 2.768 11.663 1.00 94.48 O +ATOM 17905 CB ARG J 97 42.191 4.325 13.051 1.00 86.05 C +ATOM 17906 CG ARG J 97 43.598 3.837 12.776 1.00 82.07 C +ATOM 17907 CD ARG J 97 44.346 3.541 14.068 1.00 93.91 C +ATOM 17908 NE ARG J 97 44.891 4.752 14.675 1.00 98.16 N +ATOM 17909 CZ ARG J 97 46.162 5.148 14.566 1.00108.30 C +ATOM 17910 NH1 ARG J 97 47.060 4.441 13.871 1.00 89.42 N +ATOM 17911 NH2 ARG J 97 46.542 6.283 15.146 1.00125.80 N +ATOM 17912 N ALA J 98 39.005 4.752 12.422 1.00 78.84 N +ATOM 17913 CA ALA J 98 37.670 4.241 12.630 1.00 80.00 C +ATOM 17914 C ALA J 98 36.962 4.122 11.303 1.00 72.46 C +ATOM 17915 O ALA J 98 36.052 3.294 11.126 1.00 72.11 O +ATOM 17916 CB ALA J 98 36.907 5.146 13.584 1.00 81.51 C +ATOM 17917 N ALA J 99 37.369 4.979 10.375 1.00 72.54 N +ATOM 17918 CA ALA J 99 36.775 5.019 9.030 1.00 93.95 C +ATOM 17919 C ALA J 99 37.123 3.775 8.190 1.00 81.91 C +ATOM 17920 O ALA J 99 36.249 3.120 7.636 1.00 57.90 O +ATOM 17921 CB ALA J 99 37.207 6.285 8.286 1.00 86.51 C +ATOM 17922 N GLN J 100 38.397 3.434 8.168 1.00 71.63 N +ATOM 17923 CA GLN J 100 38.895 2.512 7.171 1.00 74.58 C +ATOM 17924 C GLN J 100 39.248 1.152 7.730 1.00 83.68 C +ATOM 17925 O GLN J 100 39.823 0.317 7.028 1.00 91.21 O +ATOM 17926 CB GLN J 100 40.102 3.127 6.442 1.00 98.78 C +ATOM 17927 CG GLN J 100 41.111 3.860 7.321 1.00100.44 C +ATOM 17928 CD GLN J 100 41.867 4.962 6.574 1.00106.82 C +ATOM 17929 OE1 GLN J 100 41.275 5.951 6.064 1.00 63.55 O +ATOM 17930 NE2 GLN J 100 43.190 4.841 6.576 1.00 98.97 N +ATOM 17931 N GLU J 101 38.946 0.925 9.007 1.00101.32 N +ATOM 17932 CA GLU J 101 39.284 -0.361 9.667 1.00 97.34 C +ATOM 17933 C GLU J 101 38.511 -1.566 9.090 1.00 98.78 C +ATOM 17934 O GLU J 101 38.955 -2.696 9.189 1.00 62.65 O +ATOM 17935 CB GLU J 101 39.073 -0.268 11.185 1.00 81.08 C +ATOM 17936 CG GLU J 101 37.699 0.246 11.600 1.00 84.43 C +ATOM 17937 CD GLU J 101 37.504 0.257 13.103 1.00 88.84 C +ATOM 17938 OE1 GLU J 101 38.515 0.154 13.826 1.00114.48 O +ATOM 17939 OE2 GLU J 101 36.339 0.291 13.569 1.00 87.70 O +ATOM 17940 N ASN J 102 37.369 -1.303 8.458 1.00112.06 N +ATOM 17941 CA ASN J 102 36.536 -2.376 7.931 1.00 91.09 C +ATOM 17942 C ASN J 102 36.819 -2.696 6.478 1.00 87.48 C +ATOM 17943 O ASN J 102 36.199 -3.572 5.902 1.00 74.97 O +ATOM 17944 CB ASN J 102 35.064 -2.021 8.111 1.00 94.45 C +ATOM 17945 CG ASN J 102 34.630 -2.102 9.564 1.00108.10 C +ATOM 17946 OD1 ASN J 102 34.424 -3.193 10.121 1.00 66.01 O +ATOM 17947 ND2 ASN J 102 34.544 -0.936 10.205 1.00115.48 N +ATOM 17948 N GLY J 103 37.721 -1.945 5.860 1.00116.20 N +ATOM 17949 CA GLY J 103 38.019 -2.139 4.435 1.00126.61 C +ATOM 17950 C GLY J 103 36.829 -1.973 3.493 1.00112.33 C +ATOM 17951 O GLY J 103 36.713 -2.654 2.482 1.00 95.84 O +ATOM 17952 N THR J 104 35.938 -1.055 3.835 1.00138.16 N +ATOM 17953 CA THR J 104 34.907 -0.643 2.914 1.00136.94 C +ATOM 17954 C THR J 104 35.288 0.678 2.272 1.00 99.48 C +ATOM 17955 O THR J 104 34.889 0.935 1.155 1.00107.04 O +ATOM 17956 CB THR J 104 33.523 -0.530 3.604 1.00171.84 C +ATOM 17957 OG1 THR J 104 33.529 0.509 4.593 1.00196.02 O +ATOM 17958 CG2 THR J 104 33.132 -1.859 4.266 1.00160.60 C +ATOM 17959 N VAL J 105 36.065 1.498 2.967 1.00 78.82 N +ATOM 17960 CA VAL J 105 36.329 2.838 2.493 1.00106.05 C +ATOM 17961 C VAL J 105 36.971 2.800 1.100 1.00132.20 C +ATOM 17962 O VAL J 105 37.859 1.977 0.812 1.00 96.81 O +ATOM 17963 CB VAL J 105 37.166 3.699 3.499 1.00150.02 C +ATOM 17964 CG1 VAL J 105 38.090 4.700 2.784 1.00178.59 C +ATOM 17965 CG2 VAL J 105 36.252 4.459 4.458 1.00133.59 C +ATOM 17966 N ALA J 106 36.536 3.749 0.266 1.00163.01 N +ATOM 17967 CA ALA J 106 36.914 3.824 -1.142 1.00150.76 C +ATOM 17968 C ALA J 106 38.417 4.036 -1.312 1.00163.11 C +ATOM 17969 O ALA J 106 39.015 4.884 -0.650 1.00210.65 O +ATOM 17970 CB ALA J 106 36.143 4.946 -1.828 1.00130.23 C +ATOM 17971 N ILE J 107 39.018 3.257 -2.205 1.00160.54 N +ATOM 17972 CA ILE J 107 40.473 3.233 -2.377 1.00148.58 C +ATOM 17973 C ILE J 107 41.056 4.617 -2.740 1.00128.85 C +ATOM 17974 O ILE J 107 42.190 4.942 -2.394 1.00 96.78 O +ATOM 17975 CB ILE J 107 40.869 2.175 -3.437 1.00147.25 C +ATOM 17976 CG1 ILE J 107 42.377 1.916 -3.419 1.00137.23 C +ATOM 17977 CG2 ILE J 107 40.411 2.600 -4.832 1.00154.42 C +ATOM 17978 CD1 ILE J 107 42.922 1.467 -2.078 1.00127.06 C +ATOM 17979 N ASN J 108 40.264 5.426 -3.434 1.00129.88 N +ATOM 17980 CA ASN J 108 40.648 6.801 -3.764 1.00138.40 C +ATOM 17981 C ASN J 108 40.642 7.685 -2.523 1.00140.84 C +ATOM 17982 O ASN J 108 41.442 8.609 -2.394 1.00144.86 O +ATOM 17983 CB ASN J 108 39.679 7.396 -4.798 1.00158.91 C +ATOM 17984 CG ASN J 108 39.104 6.346 -5.735 1.00174.91 C +ATOM 17985 OD1 ASN J 108 39.697 6.032 -6.766 1.00203.08 O +ATOM 17986 ND2 ASN J 108 37.942 5.804 -5.381 1.00161.55 N +ATOM 17987 N ASN J 109 39.700 7.409 -1.633 1.00151.95 N +ATOM 17988 CA ASN J 109 39.466 8.231 -0.452 1.00149.31 C +ATOM 17989 C ASN J 109 40.356 7.846 0.727 1.00135.85 C +ATOM 17990 O ASN J 109 40.511 8.613 1.682 1.00130.87 O +ATOM 17991 CB ASN J 109 37.993 8.135 -0.047 1.00149.33 C +ATOM 17992 CG ASN J 109 37.284 9.463 -0.150 1.00164.73 C +ATOM 17993 OD1 ASN J 109 36.866 10.031 0.855 1.00210.46 O +ATOM 17994 ND2 ASN J 109 37.183 9.992 -1.366 1.00161.84 N +ATOM 17995 N ARG J 110 40.938 6.651 0.644 1.00116.43 N +ATOM 17996 CA ARG J 110 41.700 6.051 1.747 1.00 99.50 C +ATOM 17997 C ARG J 110 42.826 6.989 2.202 1.00 78.23 C +ATOM 17998 O ARG J 110 43.575 7.494 1.369 1.00 76.60 O +ATOM 17999 CB ARG J 110 42.278 4.692 1.278 1.00 97.79 C +ATOM 18000 CG ARG J 110 42.606 3.705 2.386 1.00102.70 C +ATOM 18001 CD ARG J 110 42.362 2.263 1.962 1.00114.25 C +ATOM 18002 NE ARG J 110 43.537 1.651 1.325 1.00124.18 N +ATOM 18003 CZ ARG J 110 44.178 0.563 1.775 1.00127.44 C +ATOM 18004 NH1 ARG J 110 43.771 -0.077 2.877 1.00125.29 N +ATOM 18005 NH2 ARG J 110 45.232 0.099 1.113 1.00108.31 N +ATOM 18006 N ILE J 111 42.988 7.158 3.509 1.00 64.71 N +ATOM 18007 CA ILE J 111 44.158 7.854 4.029 1.00 73.40 C +ATOM 18008 C ILE J 111 45.132 6.901 4.690 1.00 80.36 C +ATOM 18009 O ILE J 111 44.800 6.291 5.699 1.00 88.26 O +ATOM 18010 CB ILE J 111 43.756 8.908 5.058 1.00 89.85 C +ATOM 18011 CG1 ILE J 111 42.871 9.968 4.377 1.00 98.41 C +ATOM 18012 CG2 ILE J 111 45.000 9.554 5.675 1.00 93.85 C +ATOM 18013 CD1 ILE J 111 42.166 10.924 5.325 1.00 80.87 C +ATOM 18014 N PRO J 112 46.350 6.783 4.142 1.00 92.63 N +ATOM 18015 CA PRO J 112 47.334 5.876 4.724 1.00102.41 C +ATOM 18016 C PRO J 112 48.014 6.465 5.966 1.00122.82 C +ATOM 18017 O PRO J 112 48.482 7.613 5.933 1.00136.73 O +ATOM 18018 CB PRO J 112 48.343 5.707 3.596 1.00109.85 C +ATOM 18019 CG PRO J 112 48.320 7.027 2.885 1.00119.06 C +ATOM 18020 CD PRO J 112 46.943 7.614 3.078 1.00107.95 C +ATOM 18021 N LEU J 113 48.030 5.691 7.052 1.00148.04 N +ATOM 18022 CA LEU J 113 48.484 6.174 8.354 1.00116.51 C +ATOM 18023 C LEU J 113 49.784 5.546 8.787 1.00 87.67 C +ATOM 18024 O LEU J 113 50.045 4.347 8.619 1.00 62.45 O +ATOM 18025 CB LEU J 113 47.451 5.910 9.443 1.00114.12 C +ATOM 18026 CG LEU J 113 46.364 6.973 9.595 1.00109.10 C +ATOM 18027 CD1 LEU J 113 45.519 6.569 10.780 1.00128.07 C +ATOM 18028 CD2 LEU J 113 46.920 8.370 9.796 1.00 93.30 C +ATOM 18029 N GLN J 114 50.595 6.401 9.369 1.00 93.78 N +ATOM 18030 CA GLN J 114 51.968 6.089 9.628 1.00118.07 C +ATOM 18031 C GLN J 114 52.230 6.706 10.970 1.00105.98 C +ATOM 18032 O GLN J 114 51.637 7.738 11.299 1.00109.47 O +ATOM 18033 CB GLN J 114 52.873 6.706 8.550 1.00139.81 C +ATOM 18034 CG GLN J 114 54.140 5.906 8.254 1.00126.25 C +ATOM 18035 CD GLN J 114 55.231 6.786 7.669 1.00159.37 C +ATOM 18036 OE1 GLN J 114 54.935 7.823 7.061 1.00203.84 O +ATOM 18037 NE2 GLN J 114 56.488 6.445 7.942 1.00142.03 N +ATOM 18038 N SER J 115 53.098 6.064 11.740 1.00 90.96 N +ATOM 18039 CA SER J 115 53.383 6.496 13.083 1.00 88.64 C +ATOM 18040 C SER J 115 53.827 7.962 13.061 1.00 79.41 C +ATOM 18041 O SER J 115 54.362 8.453 12.049 1.00 57.26 O +ATOM 18042 CB SER J 115 54.451 5.606 13.722 1.00104.27 C +ATOM 18043 OG SER J 115 55.616 5.504 12.891 1.00181.75 O +ATOM 18044 N LEU J 116 53.649 8.654 14.185 1.00 82.21 N +ATOM 18045 CA LEU J 116 53.842 10.088 14.176 1.00 86.57 C +ATOM 18046 C LEU J 116 55.326 10.339 14.105 1.00107.79 C +ATOM 18047 O LEU J 116 56.078 9.769 14.885 1.00112.83 O +ATOM 18048 CB LEU J 116 53.265 10.754 15.412 1.00 82.19 C +ATOM 18049 CG LEU J 116 51.749 10.696 15.549 1.00 85.66 C +ATOM 18050 CD1 LEU J 116 51.324 9.482 16.412 1.00 89.21 C +ATOM 18051 CD2 LEU J 116 51.275 12.002 16.165 1.00 71.69 C +ATOM 18052 N THR J 117 55.741 11.119 13.108 1.00147.82 N +ATOM 18053 CA THR J 117 57.150 11.455 12.905 1.00136.59 C +ATOM 18054 C THR J 117 57.680 12.085 14.165 1.00100.62 C +ATOM 18055 O THR J 117 56.996 12.926 14.769 1.00 85.06 O +ATOM 18056 CB THR J 117 57.343 12.476 11.769 1.00147.75 C +ATOM 18057 OG1 THR J 117 56.729 11.994 10.565 1.00152.23 O +ATOM 18058 CG2 THR J 117 58.821 12.698 11.520 1.00150.18 C +ATOM 18059 N ALA J 118 58.849 11.626 14.598 1.00 88.60 N +ATOM 18060 CA ALA J 118 59.329 11.929 15.941 1.00 97.37 C +ATOM 18061 C ALA J 118 60.577 12.769 15.862 1.00101.44 C +ATOM 18062 O ALA J 118 61.479 12.461 15.092 1.00 76.46 O +ATOM 18063 CB ALA J 118 59.591 10.653 16.758 1.00 72.46 C +ATOM 18064 N ALA J 119 60.668 13.723 16.794 1.00109.93 N +ATOM 18065 CA ALA J 119 61.751 14.704 16.835 1.00 91.65 C +ATOM 18066 C ALA J 119 62.964 14.214 17.607 1.00 71.61 C +ATOM 18067 O ALA J 119 62.821 13.363 18.506 1.00 72.50 O +ATOM 18068 CB ALA J 119 61.239 15.985 17.455 1.00 83.74 C +ATOM 18069 N ASN J 120 64.135 14.746 17.279 1.00 66.32 N +ATOM 18070 CA ASN J 120 65.317 14.405 18.049 1.00107.04 C +ATOM 18071 C ASN J 120 65.673 15.480 19.061 1.00121.80 C +ATOM 18072 O ASN J 120 66.026 15.184 20.216 1.00161.45 O +ATOM 18073 CB ASN J 120 66.536 14.147 17.173 1.00134.06 C +ATOM 18074 CG ASN J 120 67.758 13.702 17.998 1.00129.07 C +ATOM 18075 OD1 ASN J 120 68.869 14.169 17.724 1.00185.82 O +ATOM 18076 ND2 ASN J 120 67.553 12.872 19.054 1.00 70.37 N +ATOM 18077 N ILE J 121 65.655 16.728 18.621 1.00 99.55 N +ATOM 18078 CA ILE J 121 65.858 17.814 19.558 1.00 95.89 C +ATOM 18079 C ILE J 121 64.540 18.530 19.668 1.00 95.94 C +ATOM 18080 O ILE J 121 63.792 18.644 18.700 1.00105.85 O +ATOM 18081 CB ILE J 121 66.979 18.779 19.129 1.00 98.92 C +ATOM 18082 CG1 ILE J 121 66.557 19.645 17.924 1.00113.53 C +ATOM 18083 CG2 ILE J 121 68.259 18.011 18.824 1.00 92.91 C +ATOM 18084 CD1 ILE J 121 66.363 21.106 18.266 1.00111.68 C +ATOM 18085 N MET J 122 64.213 18.967 20.869 1.00 81.37 N +ATOM 18086 CA MET J 122 63.089 19.862 21.004 1.00 66.99 C +ATOM 18087 C MET J 122 63.556 21.142 21.665 1.00 70.50 C +ATOM 18088 O MET J 122 64.510 21.144 22.464 1.00 93.72 O +ATOM 18089 CB MET J 122 61.970 19.195 21.784 1.00 68.43 C +ATOM 18090 CG MET J 122 62.348 18.686 23.173 1.00 66.73 C +ATOM 18091 SD MET J 122 60.903 18.795 24.227 1.00 84.71 S +ATOM 18092 CE MET J 122 61.563 19.348 25.769 1.00 73.31 C +ATOM 18093 N VAL J 123 62.993 22.256 21.229 1.00 75.30 N +ATOM 18094 CA VAL J 123 63.441 23.561 21.709 1.00 97.78 C +ATOM 18095 C VAL J 123 62.287 24.236 22.395 1.00107.19 C +ATOM 18096 O VAL J 123 61.225 24.391 21.824 1.00106.13 O +ATOM 18097 CB VAL J 123 63.970 24.485 20.584 1.00119.23 C +ATOM 18098 CG1 VAL J 123 63.122 24.362 19.327 1.00131.12 C +ATOM 18099 CG2 VAL J 123 64.038 25.937 21.061 1.00144.14 C +ATOM 18100 N GLU J 124 62.513 24.649 23.633 1.00131.47 N +ATOM 18101 CA GLU J 124 61.526 25.447 24.353 1.00119.41 C +ATOM 18102 C GLU J 124 62.170 26.691 24.909 1.00105.25 C +ATOM 18103 O GLU J 124 63.392 26.841 24.902 1.00120.59 O +ATOM 18104 CB GLU J 124 60.877 24.646 25.482 1.00139.85 C +ATOM 18105 CG GLU J 124 61.753 23.571 26.112 1.00146.99 C +ATOM 18106 CD GLU J 124 60.927 22.565 26.885 1.00159.63 C +ATOM 18107 OE1 GLU J 124 59.798 22.238 26.438 1.00123.74 O +ATOM 18108 OE2 GLU J 124 61.410 22.119 27.945 1.00184.57 O +ATOM 18109 N GLY J 125 61.340 27.574 25.425 1.00 83.75 N +ATOM 18110 CA GLY J 125 61.830 28.847 25.910 1.00 67.58 C +ATOM 18111 C GLY J 125 60.745 29.624 26.604 1.00 63.74 C +ATOM 18112 O GLY J 125 59.695 29.082 26.970 1.00 64.95 O +ATOM 18113 N SER J 126 60.950 30.928 26.712 1.00 65.26 N +ATOM 18114 CA SER J 126 60.014 31.765 27.430 1.00 74.75 C +ATOM 18115 C SER J 126 60.195 33.200 26.983 1.00 53.18 C +ATOM 18116 O SER J 126 61.311 33.614 26.770 1.00 45.00 O +ATOM 18117 CB SER J 126 60.253 31.618 28.951 1.00107.96 C +ATOM 18118 OG SER J 126 60.735 30.319 29.328 1.00146.61 O +ATOM 18119 N ILE J 127 59.118 33.967 27.007 1.00 46.76 N +ATOM 18120 CA ILE J 127 59.266 35.383 27.084 1.00 62.50 C +ATOM 18121 C ILE J 127 59.667 35.804 28.498 1.00 74.38 C +ATOM 18122 O ILE J 127 58.860 35.906 29.400 1.00 77.78 O +ATOM 18123 CB ILE J 127 58.000 36.126 26.664 1.00 75.54 C +ATOM 18124 CG1 ILE J 127 57.690 35.804 25.194 1.00 87.94 C +ATOM 18125 CG2 ILE J 127 58.166 37.644 26.847 1.00 80.97 C +ATOM 18126 CD1 ILE J 127 56.205 35.834 24.853 1.00 93.06 C +ATOM 18127 N ILE J 128 60.957 36.078 28.667 1.00103.37 N +ATOM 18128 CA ILE J 128 61.548 36.543 29.940 1.00 82.19 C +ATOM 18129 C ILE J 128 61.515 38.076 29.896 1.00 82.16 C +ATOM 18130 O ILE J 128 62.294 38.726 29.189 1.00146.54 O +ATOM 18131 CB ILE J 128 62.984 35.971 30.121 1.00 65.04 C +ATOM 18132 CG1 ILE J 128 63.877 36.296 28.909 1.00 78.93 C +ATOM 18133 CG2 ILE J 128 62.927 34.453 30.146 1.00 64.96 C +ATOM 18134 CD1 ILE J 128 65.356 36.293 29.223 1.00 65.81 C +ATOM 18135 N GLY J 129 60.482 38.637 30.484 1.00 59.71 N +ATOM 18136 CA GLY J 129 60.512 40.034 30.807 1.00 56.79 C +ATOM 18137 C GLY J 129 59.973 40.957 29.749 1.00 59.82 C +ATOM 18138 O GLY J 129 60.275 40.852 28.534 1.00 56.68 O +ATOM 18139 N TYR J 130 59.214 41.935 30.244 1.00 65.01 N +ATOM 18140 CA TYR J 130 58.866 43.113 29.470 1.00 86.99 C +ATOM 18141 C TYR J 130 58.886 44.217 30.480 1.00 89.76 C +ATOM 18142 O TYR J 130 58.019 44.301 31.327 1.00 83.24 O +ATOM 18143 CB TYR J 130 57.471 42.978 28.799 1.00105.90 C +ATOM 18144 CG TYR J 130 56.926 44.206 28.081 1.00 98.91 C +ATOM 18145 CD1 TYR J 130 56.527 45.340 28.800 1.00 81.40 C +ATOM 18146 CD2 TYR J 130 56.755 44.200 26.697 1.00 99.54 C +ATOM 18147 CE1 TYR J 130 56.029 46.448 28.159 1.00 81.19 C +ATOM 18148 CE2 TYR J 130 56.299 45.321 26.039 1.00104.11 C +ATOM 18149 CZ TYR J 130 55.926 46.438 26.769 1.00 91.34 C +ATOM 18150 OH TYR J 130 55.468 47.550 26.086 1.00 80.02 O +ATOM 18151 N GLU J 131 59.910 45.057 30.405 1.00130.10 N +ATOM 18152 CA GLU J 131 59.943 46.279 31.199 1.00129.64 C +ATOM 18153 C GLU J 131 59.481 47.449 30.341 1.00 87.95 C +ATOM 18154 O GLU J 131 59.655 47.435 29.128 1.00 61.11 O +ATOM 18155 CB GLU J 131 61.353 46.504 31.724 1.00145.68 C +ATOM 18156 CG GLU J 131 61.482 47.599 32.765 1.00148.46 C +ATOM 18157 CD GLU J 131 61.244 47.121 34.192 1.00148.90 C +ATOM 18158 OE1 GLU J 131 61.498 45.920 34.484 1.00119.53 O +ATOM 18159 OE2 GLU J 131 60.822 47.963 35.023 1.00166.18 O +ATOM 18160 N SER J 132 58.807 48.404 30.964 1.00 76.98 N +ATOM 18161 CA SER J 132 58.117 49.447 30.215 1.00 87.12 C +ATOM 18162 C SER J 132 58.657 50.830 30.566 1.00 92.32 C +ATOM 18163 O SER J 132 58.920 51.124 31.732 1.00109.21 O +ATOM 18164 CB SER J 132 56.595 49.386 30.454 1.00 85.08 C +ATOM 18165 OG SER J 132 56.138 50.534 31.163 1.00 75.23 O +ATOM 18166 N ASN J 133 58.742 51.696 29.562 1.00 95.39 N +ATOM 18167 CA ASN J 133 59.436 52.982 29.703 1.00 93.83 C +ATOM 18168 C ASN J 133 60.776 52.800 30.390 1.00 89.88 C +ATOM 18169 O ASN J 133 61.064 53.446 31.396 1.00 80.66 O +ATOM 18170 CB ASN J 133 58.599 53.999 30.474 1.00 87.74 C +ATOM 18171 CG ASN J 133 57.271 54.273 29.804 1.00116.19 C +ATOM 18172 OD1 ASN J 133 57.138 54.192 28.563 1.00184.34 O +ATOM 18173 ND2 ASN J 133 56.275 54.599 30.607 1.00 99.58 N +ATOM 18174 N VAL J 134 61.599 51.937 29.803 1.00 87.86 N +ATOM 18175 CA VAL J 134 62.944 51.701 30.285 1.00 98.79 C +ATOM 18176 C VAL J 134 63.768 52.976 30.079 1.00114.76 C +ATOM 18177 O VAL J 134 64.594 53.343 30.919 1.00150.08 O +ATOM 18178 CB VAL J 134 63.592 50.511 29.545 1.00120.14 C +ATOM 18179 CG1 VAL J 134 64.965 50.194 30.120 1.00132.70 C +ATOM 18180 CG2 VAL J 134 62.691 49.282 29.632 1.00140.53 C +ATOM 18181 N LYS J 135 63.488 53.685 28.985 1.00129.30 N +ATOM 18182 CA LYS J 135 63.918 55.085 28.840 1.00102.36 C +ATOM 18183 C LYS J 135 62.798 55.955 28.282 1.00 98.68 C +ATOM 18184 O LYS J 135 61.850 55.465 27.639 1.00108.53 O +ATOM 18185 CB LYS J 135 65.132 55.175 27.921 1.00 84.65 C +ATOM 18186 CG LYS J 135 66.335 54.432 28.454 1.00 78.91 C +ATOM 18187 CD LYS J 135 67.448 54.447 27.444 1.00 84.67 C +ATOM 18188 CE LYS J 135 68.660 53.698 27.962 1.00100.47 C +ATOM 18189 NZ LYS J 135 69.883 54.136 27.234 1.00123.30 N +ATOM 18190 N SER J 136 62.932 57.253 28.503 1.00 98.35 N +ATOM 18191 CA SER J 136 61.960 58.211 28.005 1.00125.50 C +ATOM 18192 C SER J 136 62.528 59.631 27.994 1.00150.52 C +ATOM 18193 O SER J 136 63.432 59.945 28.760 1.00162.15 O +ATOM 18194 CB SER J 136 60.662 58.142 28.829 1.00109.24 C +ATOM 18195 OG SER J 136 60.306 59.415 29.354 1.00112.77 O +ATOM 18196 N GLY J 137 61.965 60.488 27.144 1.00159.04 N +ATOM 18197 CA GLY J 137 62.367 61.888 27.101 1.00173.26 C +ATOM 18198 C GLY J 137 61.443 62.777 26.289 1.00187.09 C +ATOM 18199 O GLY J 137 60.445 62.318 25.732 1.00158.76 O +ATOM 18200 N GLY J 138 61.741 64.075 26.276 1.00199.34 N +ATOM 18201 CA GLY J 138 60.929 65.041 25.544 1.00179.69 C +ATOM 18202 C GLY J 138 61.629 66.373 25.359 1.00171.93 C +ATOM 18203 O GLY J 138 62.368 66.822 26.234 1.00200.66 O +ATOM 18204 N VAL J 139 61.382 67.007 24.215 1.00152.92 N +ATOM 18205 CA VAL J 139 61.912 68.342 23.925 1.00117.66 C +ATOM 18206 C VAL J 139 60.865 69.208 23.225 1.00101.62 C +ATOM 18207 O VAL J 139 60.278 68.797 22.216 1.00 81.77 O +ATOM 18208 CB VAL J 139 63.146 68.271 23.015 1.00109.94 C +ATOM 18209 CG1 VAL J 139 63.587 69.677 22.640 1.00114.06 C +ATOM 18210 CG2 VAL J 139 64.276 67.504 23.686 1.00102.30 C +ATOM 18211 N GLY J 140 60.614 70.394 23.776 1.00111.13 N +ATOM 18212 CA GLY J 140 59.585 71.291 23.241 1.00147.11 C +ATOM 18213 C GLY J 140 59.878 72.765 23.444 1.00161.72 C +ATOM 18214 O GLY J 140 60.468 73.155 24.446 1.00177.40 O +ATOM 18215 N ALA J 141 59.449 73.587 22.489 1.00187.13 N +ATOM 18216 CA ALA J 141 59.582 75.035 22.611 1.00183.72 C +ATOM 18217 C ALA J 141 58.371 75.774 22.034 1.00199.07 C +ATOM 18218 O ALA J 141 57.805 75.380 21.014 1.00214.56 O +ATOM 18219 CB ALA J 141 60.867 75.507 21.949 1.00140.86 C +ATOM 18220 N ARG J 142 57.949 76.822 22.728 1.00192.68 N +ATOM 18221 CA ARG J 142 56.957 77.726 22.187 1.00171.50 C +ATOM 18222 C ARG J 142 57.488 79.149 22.264 1.00210.24 C +ATOM 18223 O ARG J 142 58.215 79.498 23.197 1.00228.80 O +ATOM 18224 CB ARG J 142 55.624 77.606 22.924 1.00141.20 C +ATOM 18225 CG ARG J 142 54.527 78.476 22.316 1.00145.22 C +ATOM 18226 CD ARG J 142 53.183 77.776 22.243 1.00149.08 C +ATOM 18227 NE ARG J 142 52.442 77.889 23.495 1.00144.91 N +ATOM 18228 CZ ARG J 142 51.502 77.043 23.901 1.00168.42 C +ATOM 18229 NH1 ARG J 142 51.187 75.984 23.160 1.00200.71 N +ATOM 18230 NH2 ARG J 142 50.887 77.242 25.062 1.00163.35 N +ATOM 18231 N TYR J 143 57.160 79.944 21.246 1.00237.70 N +ATOM 18232 CA TYR J 143 57.713 81.286 21.085 1.00197.52 C +ATOM 18233 C TYR J 143 56.605 82.304 20.812 1.00167.86 C +ATOM 18234 O TYR J 143 56.313 82.658 19.670 1.00136.35 O +ATOM 18235 CB TYR J 143 58.739 81.285 19.952 1.00187.46 C +ATOM 18236 CG TYR J 143 59.489 82.567 19.806 1.00200.17 C +ATOM 18237 CD1 TYR J 143 60.452 82.936 20.736 1.00198.38 C +ATOM 18238 CD2 TYR J 143 59.247 83.412 18.738 1.00211.03 C +ATOM 18239 CE1 TYR J 143 61.158 84.116 20.605 1.00186.86 C +ATOM 18240 CE2 TYR J 143 59.951 84.595 18.593 1.00211.80 C +ATOM 18241 CZ TYR J 143 60.903 84.940 19.530 1.00188.44 C +ATOM 18242 OH TYR J 143 61.598 86.115 19.393 1.00182.74 O +ATOM 18243 N GLY J 145 53.908 82.610 20.220 1.00 82.00 N +ATOM 18244 CA GLY J 145 52.734 82.132 19.488 1.00121.20 C +ATOM 18245 C GLY J 145 52.844 80.786 18.773 1.00152.59 C +ATOM 18246 O GLY J 145 51.841 80.077 18.637 1.00145.68 O +ATOM 18247 N ILE J 146 54.066 80.386 18.394 1.00175.58 N +ATOM 18248 CA ILE J 146 54.290 79.163 17.596 1.00174.78 C +ATOM 18249 C ILE J 146 55.075 78.141 18.424 1.00187.46 C +ATOM 18250 O ILE J 146 56.010 78.503 19.132 1.00241.76 O +ATOM 18251 CB ILE J 146 55.075 79.458 16.295 1.00168.08 C +ATOM 18252 CG1 ILE J 146 54.608 80.785 15.674 1.00199.06 C +ATOM 18253 CG2 ILE J 146 54.907 78.319 15.297 1.00160.03 C +ATOM 18254 CD1 ILE J 146 55.472 81.973 16.024 1.00198.68 C +ATOM 18255 N GLY J 147 54.677 76.872 18.377 1.00199.26 N +ATOM 18256 CA GLY J 147 55.307 75.861 19.233 1.00194.98 C +ATOM 18257 C GLY J 147 55.332 74.451 18.682 1.00187.53 C +ATOM 18258 O GLY J 147 54.485 74.070 17.879 1.00193.30 O +ATOM 18259 N ALA J 148 56.326 73.682 19.113 1.00171.60 N +ATOM 18260 CA ALA J 148 56.405 72.276 18.771 1.00153.47 C +ATOM 18261 C ALA J 148 57.076 71.495 19.896 1.00164.41 C +ATOM 18262 O ALA J 148 57.647 72.063 20.826 1.00175.10 O +ATOM 18263 CB ALA J 148 57.162 72.080 17.469 1.00136.17 C +ATOM 18264 N ASP J 149 56.932 70.178 19.841 1.00184.37 N +ATOM 18265 CA ASP J 149 57.519 69.307 20.856 1.00146.98 C +ATOM 18266 C ASP J 149 57.506 67.858 20.389 1.00121.11 C +ATOM 18267 O ASP J 149 56.607 67.443 19.647 1.00113.81 O +ATOM 18268 CB ASP J 149 56.783 69.451 22.201 1.00147.37 C +ATOM 18269 CG ASP J 149 55.504 68.661 22.253 1.00152.75 C +ATOM 18270 OD1 ASP J 149 54.520 69.098 21.635 1.00189.87 O +ATOM 18271 OD2 ASP J 149 55.483 67.609 22.910 1.00129.25 O +ATOM 18272 N THR J 150 58.518 67.104 20.791 1.00114.06 N +ATOM 18273 CA THR J 150 58.451 65.660 20.665 1.00135.58 C +ATOM 18274 C THR J 150 58.624 65.013 22.027 1.00151.40 C +ATOM 18275 O THR J 150 59.189 65.603 22.949 1.00142.54 O +ATOM 18276 CB THR J 150 59.519 65.090 19.704 1.00131.79 C +ATOM 18277 OG1 THR J 150 60.820 65.431 20.179 1.00 99.49 O +ATOM 18278 CG2 THR J 150 59.312 65.617 18.300 1.00120.50 C +ATOM 18279 N GLN J 151 58.102 63.798 22.141 1.00168.56 N +ATOM 18280 CA GLN J 151 58.246 62.995 23.329 1.00158.98 C +ATOM 18281 C GLN J 151 58.452 61.546 22.932 1.00142.49 C +ATOM 18282 O GLN J 151 57.922 61.119 21.919 1.00140.02 O +ATOM 18283 CB GLN J 151 56.968 63.188 24.097 1.00135.42 C +ATOM 18284 CG GLN J 151 57.054 62.829 25.557 1.00155.40 C +ATOM 18285 CD GLN J 151 56.711 63.994 26.464 1.00162.90 C +ATOM 18286 OE1 GLN J 151 55.667 64.623 26.303 1.00182.46 O +ATOM 18287 NE2 GLN J 151 57.537 64.228 27.485 1.00141.47 N +ATOM 18288 N TYR J 152 59.334 60.837 23.635 1.00114.67 N +ATOM 18289 CA TYR J 152 59.612 59.458 23.278 1.00 92.11 C +ATOM 18290 C TYR J 152 59.676 58.577 24.487 1.00107.80 C +ATOM 18291 O TYR J 152 60.119 59.003 25.554 1.00133.06 O +ATOM 18292 CB TYR J 152 60.891 59.346 22.451 1.00 66.62 C +ATOM 18293 CG TYR J 152 62.093 58.799 23.156 1.00 62.03 C +ATOM 18294 CD1 TYR J 152 62.717 59.507 24.194 1.00 84.13 C +ATOM 18295 CD2 TYR J 152 62.717 57.653 22.694 1.00 56.56 C +ATOM 18296 CE1 TYR J 152 63.888 59.030 24.803 1.00 91.11 C +ATOM 18297 CE2 TYR J 152 63.909 57.182 23.270 1.00 69.68 C +ATOM 18298 CZ TYR J 152 64.506 57.877 24.316 1.00 87.30 C +ATOM 18299 OH TYR J 152 65.688 57.413 24.874 1.00 83.76 O +ATOM 18300 N GLN J 153 59.231 57.335 24.322 1.00129.33 N +ATOM 18301 CA GLN J 153 59.455 56.308 25.331 1.00138.01 C +ATOM 18302 C GLN J 153 59.929 55.010 24.681 1.00109.30 C +ATOM 18303 O GLN J 153 59.646 54.763 23.500 1.00156.73 O +ATOM 18304 CB GLN J 153 58.166 56.079 26.114 1.00151.56 C +ATOM 18305 CG GLN J 153 57.694 57.279 26.949 1.00180.91 C +ATOM 18306 CD GLN J 153 56.337 57.004 27.618 1.00211.29 C +ATOM 18307 OE1 GLN J 153 55.576 56.135 27.175 1.00258.62 O +ATOM 18308 NE2 GLN J 153 56.026 57.753 28.671 1.00204.32 N +ATOM 18309 N LEU J 154 60.687 54.210 25.422 1.00 71.09 N +ATOM 18310 CA LEU J 154 61.031 52.889 24.934 1.00 91.29 C +ATOM 18311 C LEU J 154 61.026 51.803 26.012 1.00116.16 C +ATOM 18312 O LEU J 154 61.405 52.043 27.165 1.00128.63 O +ATOM 18313 CB LEU J 154 62.372 52.910 24.214 1.00 72.39 C +ATOM 18314 CG LEU J 154 63.573 53.082 25.108 1.00 86.55 C +ATOM 18315 CD1 LEU J 154 64.199 51.739 25.455 1.00 81.08 C +ATOM 18316 CD2 LEU J 154 64.583 53.985 24.423 1.00126.32 C +ATOM 18317 N ASP J 155 60.662 50.592 25.571 1.00130.47 N +ATOM 18318 CA ASP J 155 60.382 49.439 26.428 1.00 93.05 C +ATOM 18319 C ASP J 155 61.311 48.291 26.033 1.00 85.78 C +ATOM 18320 O ASP J 155 61.862 48.299 24.938 1.00 73.06 O +ATOM 18321 CB ASP J 155 58.924 49.007 26.240 1.00 98.59 C +ATOM 18322 CG ASP J 155 57.949 50.188 26.289 1.00104.76 C +ATOM 18323 OD1 ASP J 155 57.795 50.879 25.264 1.00116.47 O +ATOM 18324 OD2 ASP J 155 57.312 50.395 27.341 1.00 92.64 O +ATOM 18325 N GLN J 156 61.475 47.306 26.912 1.00 97.81 N +ATOM 18326 CA GLN J 156 62.356 46.167 26.626 1.00 90.00 C +ATOM 18327 C GLN J 156 61.584 44.863 26.594 1.00 90.38 C +ATOM 18328 O GLN J 156 60.479 44.750 27.154 1.00 91.61 O +ATOM 18329 CB GLN J 156 63.449 46.074 27.667 1.00 97.30 C +ATOM 18330 CG GLN J 156 64.557 45.113 27.302 1.00107.63 C +ATOM 18331 CD GLN J 156 65.862 45.419 28.041 1.00137.58 C +ATOM 18332 OE1 GLN J 156 65.893 46.241 28.972 1.00132.89 O +ATOM 18333 NE2 GLN J 156 66.941 44.725 27.661 1.00110.91 N +ATOM 18334 N ILE J 157 62.135 43.887 25.893 1.00 84.53 N +ATOM 18335 CA ILE J 157 61.512 42.568 25.801 1.00 93.52 C +ATOM 18336 C ILE J 157 62.619 41.537 25.546 1.00 80.39 C +ATOM 18337 O ILE J 157 63.577 41.810 24.836 1.00 45.51 O +ATOM 18338 CB ILE J 157 60.448 42.498 24.678 1.00 95.98 C +ATOM 18339 CG1 ILE J 157 59.431 41.380 24.953 1.00117.03 C +ATOM 18340 CG2 ILE J 157 61.118 42.265 23.326 1.00102.26 C +ATOM 18341 CD1 ILE J 157 58.251 41.350 23.987 1.00126.50 C +ATOM 18342 N ALA J 158 62.541 40.399 26.224 1.00 89.11 N +ATOM 18343 CA ALA J 158 63.631 39.437 26.150 1.00 86.40 C +ATOM 18344 C ALA J 158 63.053 38.077 25.984 1.00 68.18 C +ATOM 18345 O ALA J 158 61.939 37.803 26.462 1.00100.48 O +ATOM 18346 CB ALA J 158 64.559 39.507 27.380 1.00 84.60 C +ATOM 18347 N VAL J 159 63.824 37.219 25.333 1.00 50.49 N +ATOM 18348 CA VAL J 159 63.353 35.903 25.017 1.00 65.35 C +ATOM 18349 C VAL J 159 64.444 34.877 25.237 1.00 68.08 C +ATOM 18350 O VAL J 159 65.564 35.038 24.770 1.00 64.16 O +ATOM 18351 CB VAL J 159 62.834 35.836 23.575 1.00 90.92 C +ATOM 18352 CG1 VAL J 159 62.800 34.402 23.063 1.00105.30 C +ATOM 18353 CG2 VAL J 159 61.441 36.459 23.463 1.00 94.82 C +ATOM 18354 N ASN J 160 64.102 33.823 25.984 1.00 78.15 N +ATOM 18355 CA ASN J 160 64.948 32.651 26.107 1.00 67.13 C +ATOM 18356 C ASN J 160 64.482 31.599 25.117 1.00 66.52 C +ATOM 18357 O ASN J 160 63.286 31.309 25.012 1.00 73.83 O +ATOM 18358 CB ASN J 160 64.864 32.112 27.521 1.00 75.90 C +ATOM 18359 CG ASN J 160 65.693 30.834 27.726 1.00120.30 C +ATOM 18360 OD1 ASN J 160 65.581 29.868 26.971 1.00156.90 O +ATOM 18361 ND2 ASN J 160 66.423 30.778 28.833 1.00124.88 N +ATOM 18362 N LEU J 161 65.414 31.088 24.331 1.00 64.03 N +ATOM 18363 CA LEU J 161 65.193 29.839 23.623 1.00 71.66 C +ATOM 18364 C LEU J 161 66.281 28.833 23.994 1.00 81.63 C +ATOM 18365 O LEU J 161 67.420 29.192 24.242 1.00 57.98 O +ATOM 18366 CB LEU J 161 65.209 30.066 22.119 1.00 65.57 C +ATOM 18367 CG LEU J 161 64.112 30.950 21.579 1.00 69.75 C +ATOM 18368 CD1 LEU J 161 64.364 31.246 20.108 1.00 97.84 C +ATOM 18369 CD2 LEU J 161 62.776 30.255 21.763 1.00 77.20 C +ATOM 18370 N ARG J 162 65.939 27.558 24.008 1.00100.17 N +ATOM 18371 CA ARG J 162 66.920 26.553 24.376 1.00117.50 C +ATOM 18372 C ARG J 162 66.656 25.168 23.795 1.00 99.06 C +ATOM 18373 O ARG J 162 65.547 24.652 23.835 1.00106.21 O +ATOM 18374 CB ARG J 162 67.087 26.484 25.898 1.00148.13 C +ATOM 18375 CG ARG J 162 65.876 26.044 26.708 1.00160.09 C +ATOM 18376 CD ARG J 162 66.308 25.639 28.118 1.00153.55 C +ATOM 18377 NE ARG J 162 65.229 25.029 28.901 1.00136.85 N +ATOM 18378 CZ ARG J 162 64.284 25.705 29.562 1.00124.23 C +ATOM 18379 NH1 ARG J 162 64.245 27.031 29.519 1.00123.89 N +ATOM 18380 NH2 ARG J 162 63.347 25.044 30.225 1.00104.70 N +ATOM 18381 N VAL J 163 67.711 24.609 23.214 1.00106.78 N +ATOM 18382 CA VAL J 163 67.679 23.283 22.604 1.00113.46 C +ATOM 18383 C VAL J 163 67.924 22.249 23.672 1.00113.52 C +ATOM 18384 O VAL J 163 68.993 22.219 24.279 1.00166.00 O +ATOM 18385 CB VAL J 163 68.790 23.087 21.539 1.00 99.62 C +ATOM 18386 CG1 VAL J 163 68.734 21.669 20.962 1.00 87.69 C +ATOM 18387 CG2 VAL J 163 68.671 24.162 20.460 1.00111.69 C +ATOM 18388 N VAL J 164 66.978 21.336 23.793 1.00 90.54 N +ATOM 18389 CA VAL J 164 67.105 20.236 24.691 1.00 80.32 C +ATOM 18390 C VAL J 164 67.280 18.994 23.858 1.00 67.15 C +ATOM 18391 O VAL J 164 66.472 18.713 22.952 1.00 73.99 O +ATOM 18392 CB VAL J 164 65.844 20.128 25.559 1.00130.73 C +ATOM 18393 CG1 VAL J 164 65.930 18.929 26.499 1.00172.61 C +ATOM 18394 CG2 VAL J 164 65.658 21.409 26.357 1.00124.07 C +ATOM 18395 N ASN J 165 68.204 18.159 24.292 1.00 63.32 N +ATOM 18396 CA ASN J 165 68.318 16.823 23.722 1.00 82.95 C +ATOM 18397 C ASN J 165 67.311 15.800 24.292 1.00 87.50 C +ATOM 18398 O ASN J 165 67.375 15.449 25.479 1.00 87.39 O +ATOM 18399 CB ASN J 165 69.727 16.276 23.936 1.00 86.00 C +ATOM 18400 CG ASN J 165 69.951 14.985 23.199 1.00 76.45 C +ATOM 18401 OD1 ASN J 165 69.229 14.687 22.219 1.00143.97 O +ATOM 18402 ND2 ASN J 165 71.043 14.325 23.516 1.00 64.90 N +ATOM 18403 N VAL J 166 66.435 15.289 23.426 1.00 78.59 N +ATOM 18404 CA VAL J 166 65.440 14.331 23.817 1.00 70.31 C +ATOM 18405 C VAL J 166 66.111 13.118 24.424 1.00 79.97 C +ATOM 18406 O VAL J 166 65.571 12.528 25.376 1.00159.59 O +ATOM 18407 CB VAL J 166 64.581 13.912 22.613 1.00 90.66 C +ATOM 18408 CG1 VAL J 166 63.930 12.527 22.803 1.00100.72 C +ATOM 18409 CG2 VAL J 166 63.544 14.997 22.321 1.00 86.65 C +ATOM 18410 N SER J 167 67.255 12.714 23.868 1.00 58.41 N +ATOM 18411 CA SER J 167 67.829 11.421 24.184 1.00 62.99 C +ATOM 18412 C SER J 167 68.487 11.424 25.563 1.00 83.55 C +ATOM 18413 O SER J 167 68.763 10.341 26.136 1.00 79.44 O +ATOM 18414 CB SER J 167 68.837 11.018 23.120 1.00 59.18 C +ATOM 18415 OG SER J 167 68.301 11.186 21.820 1.00 49.93 O +ATOM 18416 N THR J 168 68.671 12.618 26.134 1.00 85.27 N +ATOM 18417 CA THR J 168 69.295 12.730 27.467 1.00 93.04 C +ATOM 18418 C THR J 168 68.592 13.701 28.438 1.00 87.19 C +ATOM 18419 O THR J 168 68.643 13.540 29.663 1.00102.15 O +ATOM 18420 CB THR J 168 70.761 13.158 27.311 1.00 82.51 C +ATOM 18421 OG1 THR J 168 70.812 14.312 26.480 1.00 54.00 O +ATOM 18422 CG2 THR J 168 71.582 12.024 26.695 1.00 92.25 C +ATOM 18423 N GLY J 169 68.021 14.760 27.899 1.00 69.05 N +ATOM 18424 CA GLY J 169 67.567 15.835 28.736 1.00 66.33 C +ATOM 18425 C GLY J 169 68.614 16.923 28.906 1.00 78.90 C +ATOM 18426 O GLY J 169 68.321 17.980 29.471 1.00109.86 O +ATOM 18427 N GLU J 170 69.864 16.649 28.513 1.00 77.02 N +ATOM 18428 CA GLU J 170 70.908 17.697 28.484 1.00 68.45 C +ATOM 18429 C GLU J 170 70.336 18.827 27.674 1.00 65.31 C +ATOM 18430 O GLU J 170 69.870 18.625 26.548 1.00 82.68 O +ATOM 18431 CB GLU J 170 72.222 17.187 27.843 1.00 74.26 C +ATOM 18432 CG GLU J 170 73.082 16.319 28.756 1.00 86.10 C +ATOM 18433 CD GLU J 170 73.799 15.155 28.058 1.00 81.41 C +ATOM 18434 OE1 GLU J 170 73.467 14.854 26.899 1.00 65.43 O +ATOM 18435 OE2 GLU J 170 74.616 14.469 28.718 1.00 50.02 O +ATOM 18436 N ILE J 171 70.364 20.023 28.223 1.00 62.65 N +ATOM 18437 CA ILE J 171 70.207 21.185 27.388 1.00 88.50 C +ATOM 18438 C ILE J 171 71.445 21.334 26.480 1.00 98.12 C +ATOM 18439 O ILE J 171 72.564 21.389 26.981 1.00 85.67 O +ATOM 18440 CB ILE J 171 70.010 22.440 28.248 1.00 79.48 C +ATOM 18441 CG1 ILE J 171 68.643 22.355 28.894 1.00 91.57 C +ATOM 18442 CG2 ILE J 171 70.123 23.685 27.382 1.00 87.12 C +ATOM 18443 CD1 ILE J 171 68.482 23.318 30.036 1.00104.97 C +ATOM 18444 N LEU J 172 71.244 21.372 25.157 1.00 86.45 N +ATOM 18445 CA LEU J 172 72.362 21.485 24.239 1.00 86.08 C +ATOM 18446 C LEU J 172 72.747 22.954 23.901 1.00111.70 C +ATOM 18447 O LEU J 172 73.809 23.239 23.302 1.00101.13 O +ATOM 18448 CB LEU J 172 72.092 20.693 22.955 1.00 68.38 C +ATOM 18449 CG LEU J 172 72.489 19.208 22.877 1.00 72.49 C +ATOM 18450 CD1 LEU J 172 72.478 18.647 24.266 1.00 68.44 C +ATOM 18451 CD2 LEU J 172 71.736 18.345 21.888 1.00 93.84 C +ATOM 18452 N SER J 173 71.868 23.885 24.261 1.00 95.00 N +ATOM 18453 CA SER J 173 72.100 25.306 23.991 1.00 66.24 C +ATOM 18454 C SER J 173 71.035 26.166 24.642 1.00 66.01 C +ATOM 18455 O SER J 173 69.837 25.907 24.506 1.00110.08 O +ATOM 18456 CB SER J 173 72.067 25.573 22.482 1.00 64.21 C +ATOM 18457 OG SER J 173 71.935 26.956 22.225 1.00 59.56 O +ATOM 18458 N SER J 174 71.456 27.210 25.321 1.00 77.85 N +ATOM 18459 CA SER J 174 70.520 28.228 25.807 1.00 88.90 C +ATOM 18460 C SER J 174 70.960 29.561 25.263 1.00116.09 C +ATOM 18461 O SER J 174 72.161 29.890 25.275 1.00156.88 O +ATOM 18462 CB SER J 174 70.493 28.282 27.353 1.00 95.54 C +ATOM 18463 OG SER J 174 69.448 29.098 27.858 1.00 64.76 O +ATOM 18464 N VAL J 175 69.996 30.347 24.806 1.00108.51 N +ATOM 18465 CA VAL J 175 70.289 31.691 24.302 1.00109.62 C +ATOM 18466 C VAL J 175 69.299 32.722 24.811 1.00100.79 C +ATOM 18467 O VAL J 175 68.099 32.434 24.954 1.00159.85 O +ATOM 18468 CB VAL J 175 70.300 31.720 22.758 1.00125.58 C +ATOM 18469 CG1 VAL J 175 71.413 30.833 22.222 1.00125.63 C +ATOM 18470 CG2 VAL J 175 68.972 31.262 22.190 1.00152.35 C +ATOM 18471 N ASN J 176 69.797 33.933 25.043 1.00 86.64 N +ATOM 18472 CA ASN J 176 68.997 35.007 25.629 1.00110.89 C +ATOM 18473 C ASN J 176 68.994 36.291 24.775 1.00102.77 C +ATOM 18474 O ASN J 176 69.856 37.124 24.960 1.00123.65 O +ATOM 18475 CB ASN J 176 69.542 35.293 27.042 1.00108.34 C +ATOM 18476 CG ASN J 176 68.741 34.573 28.134 1.00 92.37 C +ATOM 18477 OD1 ASN J 176 68.019 33.638 27.808 1.00106.73 O +ATOM 18478 ND2 ASN J 176 68.908 34.947 29.420 1.00 82.72 N +ATOM 18479 N THR J 177 67.967 36.486 23.944 1.00 94.80 N +ATOM 18480 CA THR J 177 67.893 37.658 23.078 1.00 80.19 C +ATOM 18481 C THR J 177 66.993 38.738 23.639 1.00 78.28 C +ATOM 18482 O THR J 177 66.189 38.486 24.544 1.00109.61 O +ATOM 18483 CB THR J 177 67.366 37.290 21.689 1.00104.45 C +ATOM 18484 OG1 THR J 177 65.975 36.951 21.760 1.00106.61 O +ATOM 18485 CG2 THR J 177 68.145 36.100 21.095 1.00108.19 C +ATOM 18486 N SER J 178 67.163 39.953 23.139 1.00 83.55 N +ATOM 18487 CA SER J 178 66.475 41.122 23.688 1.00103.70 C +ATOM 18488 C SER J 178 66.190 42.124 22.598 1.00 92.36 C +ATOM 18489 O SER J 178 66.946 42.257 21.634 1.00 86.00 O +ATOM 18490 CB SER J 178 67.299 41.797 24.818 1.00123.67 C +ATOM 18491 OG SER J 178 66.789 43.091 25.144 1.00123.38 O +ATOM 18492 N LYS J 179 65.162 42.924 22.809 1.00110.08 N +ATOM 18493 CA LYS J 179 64.758 43.877 21.793 1.00128.02 C +ATOM 18494 C LYS J 179 63.995 45.053 22.402 1.00104.76 C +ATOM 18495 O LYS J 179 63.280 44.923 23.393 1.00131.71 O +ATOM 18496 CB LYS J 179 63.893 43.148 20.773 1.00150.26 C +ATOM 18497 CG LYS J 179 64.073 43.613 19.342 1.00155.38 C +ATOM 18498 CD LYS J 179 63.033 44.657 18.989 1.00123.85 C +ATOM 18499 CE LYS J 179 63.315 45.234 17.624 1.00109.65 C +ATOM 18500 NZ LYS J 179 62.509 46.454 17.387 1.00114.90 N +ATOM 18501 N THR J 180 64.153 46.203 21.785 1.00 65.45 N +ATOM 18502 CA THR J 180 63.590 47.399 22.289 1.00 77.45 C +ATOM 18503 C THR J 180 62.394 47.835 21.452 1.00 87.28 C +ATOM 18504 O THR J 180 62.515 47.982 20.242 1.00 81.33 O +ATOM 18505 CB THR J 180 64.626 48.527 22.100 1.00 86.03 C +ATOM 18506 OG1 THR J 180 65.905 48.057 22.493 1.00 52.79 O +ATOM 18507 CG2 THR J 180 64.260 49.803 22.872 1.00 80.06 C +ATOM 18508 N ILE J 181 61.328 48.252 22.133 1.00100.60 N +ATOM 18509 CA ILE J 181 60.140 48.796 21.476 1.00102.51 C +ATOM 18510 C ILE J 181 60.111 50.332 21.570 1.00 85.05 C +ATOM 18511 O ILE J 181 59.998 50.899 22.659 1.00101.98 O +ATOM 18512 CB ILE J 181 58.839 48.183 22.084 1.00109.50 C +ATOM 18513 CG1 ILE J 181 58.938 46.657 22.104 1.00118.20 C +ATOM 18514 CG2 ILE J 181 57.610 48.584 21.295 1.00105.32 C +ATOM 18515 CD1 ILE J 181 58.861 46.068 23.491 1.00123.45 C +ATOM 18516 N LEU J 182 60.197 50.986 20.417 1.00 78.68 N +ATOM 18517 CA LEU J 182 60.173 52.451 20.337 1.00 93.25 C +ATOM 18518 C LEU J 182 58.780 53.081 20.188 1.00 98.77 C +ATOM 18519 O LEU J 182 57.945 52.617 19.394 1.00100.22 O +ATOM 18520 CB LEU J 182 61.040 52.908 19.164 1.00 93.91 C +ATOM 18521 CG LEU J 182 61.127 54.428 18.944 1.00 77.65 C +ATOM 18522 CD1 LEU J 182 61.746 55.157 20.114 1.00 74.62 C +ATOM 18523 CD2 LEU J 182 61.924 54.646 17.677 1.00 89.81 C +ATOM 18524 N SER J 183 58.584 54.197 20.882 1.00112.10 N +ATOM 18525 CA SER J 183 57.380 55.000 20.745 1.00147.48 C +ATOM 18526 C SER J 183 57.743 56.488 20.753 1.00156.86 C +ATOM 18527 O SER J 183 58.590 56.920 21.527 1.00174.20 O +ATOM 18528 CB SER J 183 56.399 54.686 21.885 1.00146.05 C +ATOM 18529 OG SER J 183 56.413 53.299 22.195 1.00151.46 O +ATOM 18530 N TYR J 184 57.075 57.275 19.911 1.00166.35 N +ATOM 18531 CA TYR J 184 57.267 58.731 19.902 1.00127.93 C +ATOM 18532 C TYR J 184 56.069 59.545 19.412 1.00109.88 C +ATOM 18533 O TYR J 184 55.169 59.043 18.716 1.00 94.82 O +ATOM 18534 CB TYR J 184 58.496 59.120 19.082 1.00118.07 C +ATOM 18535 CG TYR J 184 58.453 58.698 17.639 1.00112.95 C +ATOM 18536 CD1 TYR J 184 57.771 59.461 16.679 1.00 90.19 C +ATOM 18537 CD2 TYR J 184 59.088 57.538 17.227 1.00100.00 C +ATOM 18538 CE1 TYR J 184 57.713 59.071 15.354 1.00 64.46 C +ATOM 18539 CE2 TYR J 184 59.037 57.149 15.901 1.00 95.27 C +ATOM 18540 CZ TYR J 184 58.361 57.929 14.973 1.00 70.30 C +ATOM 18541 OH TYR J 184 58.240 57.473 13.685 1.00 83.68 O +ATOM 18542 N GLU J 185 56.045 60.790 19.865 1.00115.18 N +ATOM 18543 CA GLU J 185 54.914 61.673 19.687 1.00153.73 C +ATOM 18544 C GLU J 185 55.389 63.058 19.292 1.00186.13 C +ATOM 18545 O GLU J 185 56.003 63.766 20.083 1.00257.16 O +ATOM 18546 CB GLU J 185 54.088 61.691 20.979 1.00157.49 C +ATOM 18547 CG GLU J 185 52.977 62.720 21.075 1.00155.27 C +ATOM 18548 CD GLU J 185 52.085 62.465 22.281 1.00153.88 C +ATOM 18549 OE1 GLU J 185 52.310 61.464 23.001 1.00122.83 O +ATOM 18550 OE2 GLU J 185 51.163 63.268 22.515 1.00170.26 O +ATOM 18551 N VAL J 186 55.155 63.405 18.032 1.00189.95 N +ATOM 18552 CA VAL J 186 55.543 64.700 17.488 1.00167.43 C +ATOM 18553 C VAL J 186 54.322 65.596 17.382 1.00146.21 C +ATOM 18554 O VAL J 186 53.222 65.148 17.053 1.00131.55 O +ATOM 18555 CB VAL J 186 56.165 64.564 16.092 1.00159.45 C +ATOM 18556 CG1 VAL J 186 56.734 65.899 15.635 1.00150.47 C +ATOM 18557 CG2 VAL J 186 57.245 63.497 16.097 1.00145.58 C +ATOM 18558 N GLN J 187 54.500 66.861 17.725 1.00133.80 N +ATOM 18559 CA GLN J 187 53.364 67.731 17.826 1.00148.24 C +ATOM 18560 C GLN J 187 53.758 69.198 17.580 1.00155.97 C +ATOM 18561 O GLN J 187 54.832 69.655 17.999 1.00209.19 O +ATOM 18562 CB GLN J 187 52.668 67.484 19.158 1.00146.09 C +ATOM 18563 CG GLN J 187 51.515 68.411 19.399 1.00145.00 C +ATOM 18564 CD GLN J 187 50.904 68.203 20.759 1.00162.36 C +ATOM 18565 OE1 GLN J 187 51.596 67.836 21.702 1.00156.17 O +ATOM 18566 NE2 GLN J 187 49.586 68.369 20.853 1.00182.36 N +ATOM 18567 N ALA J 188 52.944 69.894 16.787 1.00177.80 N +ATOM 18568 CA ALA J 188 53.212 71.296 16.462 1.00157.45 C +ATOM 18569 C ALA J 188 51.910 72.092 16.446 1.00164.80 C +ATOM 18570 O ALA J 188 50.876 71.595 16.008 1.00164.99 O +ATOM 18571 CB ALA J 188 53.927 71.411 15.123 1.00112.49 C +ATOM 18572 N GLY J 189 51.956 73.314 16.959 1.00176.44 N +ATOM 18573 CA GLY J 189 50.784 74.175 16.982 1.00189.17 C +ATOM 18574 C GLY J 189 51.129 75.631 16.753 1.00210.93 C +ATOM 18575 O GLY J 189 52.117 76.135 17.285 1.00230.67 O +ATOM 18576 N VAL J 190 50.308 76.307 15.957 1.00230.42 N +ATOM 18577 CA VAL J 190 50.464 77.732 15.717 1.00209.51 C +ATOM 18578 C VAL J 190 49.263 78.487 16.311 1.00212.22 C +ATOM 18579 O VAL J 190 48.113 78.068 16.134 1.00211.97 O +ATOM 18580 CB VAL J 190 50.595 78.028 14.207 1.00169.53 C +ATOM 18581 CG1 VAL J 190 50.997 79.474 14.000 1.00184.86 C +ATOM 18582 CG2 VAL J 190 51.587 77.076 13.542 1.00117.34 C +ATOM 18583 N PHE J 191 49.536 79.587 17.013 1.00204.09 N +ATOM 18584 CA PHE J 191 48.508 80.303 17.781 1.00215.39 C +ATOM 18585 C PHE J 191 48.631 81.835 17.605 1.00243.62 C +ATOM 18586 O PHE J 191 49.708 82.361 17.601 1.00234.13 O +ATOM 18587 CB PHE J 191 48.666 79.965 19.271 1.00190.97 C +ATOM 18588 CG PHE J 191 47.419 80.215 20.095 1.00186.08 C +ATOM 18589 CD1 PHE J 191 47.019 81.509 20.407 1.00160.96 C +ATOM 18590 CD2 PHE J 191 46.661 79.161 20.574 1.00188.02 C +ATOM 18591 CE1 PHE J 191 45.877 81.750 21.154 1.00135.41 C +ATOM 18592 CE2 PHE J 191 45.532 79.396 21.346 1.00171.05 C +ATOM 18593 CZ PHE J 191 45.139 80.692 21.633 1.00145.27 C +ATOM 18594 N ARG J 192 47.523 82.570 17.536 1.00236.62 N +ATOM 18595 CA ARG J 192 47.564 84.047 17.505 1.00182.76 C +ATOM 18596 C ARG J 192 46.243 84.650 17.994 1.00146.16 C +ATOM 18597 O ARG J 192 46.179 85.818 18.360 1.00114.71 O +ATOM 18598 CB ARG J 192 47.904 84.544 16.085 1.00167.67 C +ATOM 18599 CG ARG J 192 49.362 84.942 15.873 1.00143.89 C +ATOM 18600 CD ARG J 192 49.888 84.518 14.517 1.00128.27 C +ATOM 18601 NE ARG J 192 51.342 84.495 14.540 1.00140.65 N +ATOM 18602 CZ ARG J 192 52.105 83.512 14.065 1.00146.55 C +ATOM 18603 NH1 ARG J 192 51.563 82.490 13.420 1.00162.43 N +ATOM 18604 NH2 ARG J 192 53.431 83.615 14.143 1.00146.38 N +ATOM 18605 N LEU J 200 43.649 82.950 15.765 1.00 96.81 N +ATOM 18606 CA LEU J 200 43.883 81.911 14.770 1.00125.38 C +ATOM 18607 C LEU J 200 44.731 80.780 15.343 1.00166.07 C +ATOM 18608 O LEU J 200 45.900 80.974 15.675 1.00215.46 O +ATOM 18609 CB LEU J 200 44.561 82.499 13.531 1.00123.09 C +ATOM 18610 CG LEU J 200 45.448 81.547 12.726 1.00134.98 C +ATOM 18611 CD1 LEU J 200 45.516 81.977 11.269 1.00123.01 C +ATOM 18612 CD2 LEU J 200 46.841 81.469 13.332 1.00126.32 C +ATOM 18613 N GLU J 201 44.133 79.598 15.456 1.00187.72 N +ATOM 18614 CA GLU J 201 44.833 78.431 15.990 1.00195.67 C +ATOM 18615 C GLU J 201 44.947 77.351 14.921 1.00207.57 C +ATOM 18616 O GLU J 201 44.077 77.230 14.065 1.00181.52 O +ATOM 18617 CB GLU J 201 44.107 77.862 17.208 1.00185.27 C +ATOM 18618 CG GLU J 201 44.997 76.968 18.062 1.00173.15 C +ATOM 18619 CD GLU J 201 44.278 76.390 19.271 1.00178.65 C +ATOM 18620 OE1 GLU J 201 43.662 77.170 20.038 1.00206.62 O +ATOM 18621 OE2 GLU J 201 44.380 75.168 19.497 1.00136.30 O +ATOM 18622 N GLY J 202 46.038 76.593 14.964 1.00221.25 N +ATOM 18623 CA GLY J 202 46.209 75.435 14.088 1.00214.74 C +ATOM 18624 C GLY J 202 47.149 74.412 14.694 1.00216.14 C +ATOM 18625 O GLY J 202 48.265 74.749 15.091 1.00240.32 O +ATOM 18626 N GLU J 203 46.692 73.166 14.803 1.00201.51 N +ATOM 18627 CA GLU J 203 47.476 72.125 15.463 1.00165.46 C +ATOM 18628 C GLU J 203 47.595 70.845 14.639 1.00138.12 C +ATOM 18629 O GLU J 203 46.616 70.348 14.076 1.00109.25 O +ATOM 18630 CB GLU J 203 46.882 71.795 16.832 1.00177.15 C +ATOM 18631 CG GLU J 203 46.985 72.947 17.832 1.00180.02 C +ATOM 18632 CD GLU J 203 46.479 72.613 19.229 1.00164.14 C +ATOM 18633 OE1 GLU J 203 45.926 71.506 19.414 1.00140.75 O +ATOM 18634 OE2 GLU J 203 46.647 73.458 20.137 1.00136.89 O +ATOM 18635 N VAL J 204 48.817 70.331 14.581 1.00129.95 N +ATOM 18636 CA VAL J 204 49.105 69.057 13.941 1.00132.65 C +ATOM 18637 C VAL J 204 49.804 68.160 14.954 1.00174.71 C +ATOM 18638 O VAL J 204 50.693 68.602 15.696 1.00232.78 O +ATOM 18639 CB VAL J 204 49.994 69.249 12.693 1.00114.98 C +ATOM 18640 CG1 VAL J 204 50.637 67.936 12.246 1.00109.99 C +ATOM 18641 CG2 VAL J 204 49.171 69.865 11.570 1.00 97.91 C +ATOM 18642 N GLY J 205 49.388 66.899 14.991 1.00202.41 N +ATOM 18643 CA GLY J 205 50.013 65.909 15.859 1.00200.96 C +ATOM 18644 C GLY J 205 50.213 64.576 15.148 1.00185.91 C +ATOM 18645 O GLY J 205 49.447 64.213 14.253 1.00147.54 O +ATOM 18646 N TYR J 206 51.248 63.847 15.550 1.00168.41 N +ATOM 18647 CA TYR J 206 51.487 62.497 15.044 1.00147.64 C +ATOM 18648 C TYR J 206 52.122 61.641 16.123 1.00170.66 C +ATOM 18649 O TYR J 206 52.954 62.122 16.882 1.00190.65 O +ATOM 18650 CB TYR J 206 52.413 62.531 13.836 1.00131.52 C +ATOM 18651 CG TYR J 206 52.758 61.151 13.320 1.00127.77 C +ATOM 18652 CD1 TYR J 206 51.823 60.394 12.584 1.00114.89 C +ATOM 18653 CD2 TYR J 206 54.014 60.601 13.565 1.00123.23 C +ATOM 18654 CE1 TYR J 206 52.147 59.154 12.072 1.00108.17 C +ATOM 18655 CE2 TYR J 206 54.344 59.354 13.071 1.00145.87 C +ATOM 18656 CZ TYR J 206 53.409 58.639 12.327 1.00151.76 C +ATOM 18657 OH TYR J 206 53.762 57.395 11.858 1.00213.80 O +ATOM 18658 N THR J 207 51.730 60.371 16.193 1.00177.87 N +ATOM 18659 CA THR J 207 52.297 59.447 17.179 1.00152.48 C +ATOM 18660 C THR J 207 52.567 58.071 16.565 1.00129.58 C +ATOM 18661 O THR J 207 51.755 57.560 15.780 1.00110.63 O +ATOM 18662 CB THR J 207 51.357 59.261 18.388 1.00157.65 C +ATOM 18663 OG1 THR J 207 50.117 58.692 17.955 1.00145.29 O +ATOM 18664 CG2 THR J 207 51.077 60.582 19.069 1.00151.43 C +ATOM 18665 N SER J 208 53.718 57.486 16.900 1.00100.15 N +ATOM 18666 CA SER J 208 54.070 56.167 16.375 1.00101.85 C +ATOM 18667 C SER J 208 54.577 55.239 17.452 1.00 97.33 C +ATOM 18668 O SER J 208 55.523 55.564 18.155 1.00 99.44 O +ATOM 18669 CB SER J 208 55.104 56.266 15.248 1.00104.89 C +ATOM 18670 OG SER J 208 55.563 54.976 14.845 1.00109.05 O +ATOM 18671 N ASN J 209 53.941 54.071 17.539 1.00131.41 N +ATOM 18672 CA ASN J 209 54.385 52.975 18.394 1.00122.18 C +ATOM 18673 C ASN J 209 54.856 51.801 17.560 1.00113.24 C +ATOM 18674 O ASN J 209 54.202 51.426 16.577 1.00152.50 O +ATOM 18675 CB ASN J 209 53.238 52.485 19.276 1.00102.32 C +ATOM 18676 CG ASN J 209 52.846 53.491 20.322 1.00 88.62 C +ATOM 18677 OD1 ASN J 209 53.490 53.597 21.366 1.00133.16 O +ATOM 18678 ND2 ASN J 209 51.815 54.240 20.047 1.00 66.42 N +ATOM 18679 N GLU J 210 55.984 51.226 17.943 1.00 82.25 N +ATOM 18680 CA GLU J 210 56.370 49.949 17.377 1.00 93.45 C +ATOM 18681 C GLU J 210 55.376 48.907 17.845 1.00101.77 C +ATOM 18682 O GLU J 210 54.917 48.936 18.985 1.00122.61 O +ATOM 18683 CB GLU J 210 57.779 49.573 17.820 1.00107.69 C +ATOM 18684 CG GLU J 210 58.673 49.012 16.733 1.00128.11 C +ATOM 18685 CD GLU J 210 60.150 49.053 17.119 1.00173.49 C +ATOM 18686 OE1 GLU J 210 60.585 49.934 17.926 1.00194.35 O +ATOM 18687 OE2 GLU J 210 60.904 48.227 16.566 1.00254.05 O +ATOM 18688 N PRO J 211 55.031 47.965 16.968 1.00137.14 N +ATOM 18689 CA PRO J 211 54.244 46.828 17.431 1.00161.86 C +ATOM 18690 C PRO J 211 55.056 45.851 18.297 1.00176.29 C +ATOM 18691 O PRO J 211 56.125 45.385 17.877 1.00175.64 O +ATOM 18692 CB PRO J 211 53.804 46.150 16.127 1.00171.79 C +ATOM 18693 CG PRO J 211 54.010 47.168 15.058 1.00142.11 C +ATOM 18694 CD PRO J 211 55.202 47.947 15.510 1.00147.47 C +ATOM 18695 N VAL J 212 54.540 45.550 19.489 1.00136.46 N +ATOM 18696 CA VAL J 212 55.217 44.653 20.425 1.00109.08 C +ATOM 18697 C VAL J 212 55.242 43.288 19.793 1.00 91.60 C +ATOM 18698 O VAL J 212 56.217 42.532 19.882 1.00 75.69 O +ATOM 18699 CB VAL J 212 54.470 44.589 21.773 1.00 93.72 C +ATOM 18700 CG1 VAL J 212 55.261 43.734 22.762 1.00 92.40 C +ATOM 18701 CG2 VAL J 212 54.259 45.993 22.352 1.00128.12 C +ATOM 18702 N MET J 213 54.111 42.979 19.179 1.00 88.55 N +ATOM 18703 CA MET J 213 53.925 41.829 18.272 1.00104.75 C +ATOM 18704 C MET J 213 55.134 41.547 17.364 1.00 85.31 C +ATOM 18705 O MET J 213 55.661 40.439 17.303 1.00 56.45 O +ATOM 18706 CB MET J 213 52.700 42.213 17.443 1.00137.61 C +ATOM 18707 CG MET J 213 52.171 41.223 16.449 1.00180.56 C +ATOM 18708 SD MET J 213 50.750 42.056 15.655 1.00204.02 S +ATOM 18709 CE MET J 213 51.497 42.235 14.054 1.00206.58 C +ATOM 18710 N LEU J 214 55.631 42.614 16.769 1.00111.73 N +ATOM 18711 CA LEU J 214 56.577 42.515 15.678 1.00136.20 C +ATOM 18712 C LEU J 214 57.963 42.425 16.260 1.00120.55 C +ATOM 18713 O LEU J 214 58.865 41.837 15.663 1.00137.40 O +ATOM 18714 CB LEU J 214 56.438 43.743 14.752 1.00186.47 C +ATOM 18715 CG LEU J 214 56.479 43.543 13.232 1.00210.21 C +ATOM 18716 CD1 LEU J 214 55.372 42.608 12.741 1.00246.85 C +ATOM 18717 CD2 LEU J 214 56.378 44.892 12.526 1.00192.32 C +ATOM 18718 N CYS J 215 58.138 43.039 17.423 1.00116.26 N +ATOM 18719 CA CYS J 215 59.420 42.996 18.123 1.00151.59 C +ATOM 18720 C CYS J 215 59.659 41.602 18.691 1.00152.87 C +ATOM 18721 O CYS J 215 60.800 41.076 18.684 1.00114.03 O +ATOM 18722 CB CYS J 215 59.438 44.017 19.260 1.00159.76 C +ATOM 18723 SG CYS J 215 59.338 45.727 18.711 1.00146.81 S +ATOM 18724 N LEU J 216 58.587 41.028 19.238 1.00136.01 N +ATOM 18725 CA LEU J 216 58.646 39.668 19.740 1.00132.86 C +ATOM 18726 C LEU J 216 59.078 38.741 18.606 1.00137.74 C +ATOM 18727 O LEU J 216 60.008 37.934 18.761 1.00129.96 O +ATOM 18728 CB LEU J 216 57.298 39.246 20.297 1.00114.34 C +ATOM 18729 CG LEU J 216 57.241 37.793 20.790 1.00118.95 C +ATOM 18730 CD1 LEU J 216 58.264 37.493 21.869 1.00104.82 C +ATOM 18731 CD2 LEU J 216 55.838 37.484 21.305 1.00132.65 C +ATOM 18732 N MET J 217 58.467 38.935 17.436 1.00121.81 N +ATOM 18733 CA MET J 217 58.728 38.057 16.299 1.00132.15 C +ATOM 18734 C MET J 217 60.170 38.189 15.836 1.00112.39 C +ATOM 18735 O MET J 217 60.878 37.185 15.696 1.00 94.84 O +ATOM 18736 CB MET J 217 57.777 38.366 15.144 1.00152.05 C +ATOM 18737 CG MET J 217 57.219 37.116 14.469 1.00147.00 C +ATOM 18738 SD MET J 217 58.477 36.210 13.553 1.00137.65 S +ATOM 18739 CE MET J 217 57.622 34.691 13.131 1.00179.77 C +ATOM 18740 N SER J 218 60.626 39.431 15.719 1.00102.07 N +ATOM 18741 CA SER J 218 62.018 39.718 15.382 1.00139.69 C +ATOM 18742 C SER J 218 63.024 39.022 16.330 1.00153.87 C +ATOM 18743 O SER J 218 63.963 38.349 15.886 1.00130.62 O +ATOM 18744 CB SER J 218 62.262 41.233 15.400 1.00130.29 C +ATOM 18745 OG SER J 218 63.523 41.558 14.831 1.00136.05 O +ATOM 18746 N ALA J 219 62.823 39.204 17.631 1.00120.26 N +ATOM 18747 CA ALA J 219 63.753 38.693 18.615 1.00 93.91 C +ATOM 18748 C ALA J 219 63.799 37.152 18.583 1.00106.56 C +ATOM 18749 O ALA J 219 64.845 36.528 18.821 1.00 94.54 O +ATOM 18750 CB ALA J 219 63.356 39.209 19.985 1.00 87.61 C +ATOM 18751 N ILE J 220 62.656 36.523 18.319 1.00111.80 N +ATOM 18752 CA ILE J 220 62.602 35.058 18.260 1.00115.87 C +ATOM 18753 C ILE J 220 63.413 34.550 17.064 1.00117.74 C +ATOM 18754 O ILE J 220 64.123 33.545 17.164 1.00 80.91 O +ATOM 18755 CB ILE J 220 61.144 34.542 18.200 1.00132.09 C +ATOM 18756 CG1 ILE J 220 60.447 34.802 19.549 1.00110.37 C +ATOM 18757 CG2 ILE J 220 61.107 33.048 17.825 1.00109.68 C +ATOM 18758 CD1 ILE J 220 58.940 34.715 19.493 1.00114.23 C +ATOM 18759 N GLU J 221 63.302 35.252 15.933 1.00114.26 N +ATOM 18760 CA GLU J 221 64.066 34.899 14.731 1.00100.85 C +ATOM 18761 C GLU J 221 65.554 34.941 15.051 1.00113.71 C +ATOM 18762 O GLU J 221 66.296 33.974 14.789 1.00 83.22 O +ATOM 18763 CB GLU J 221 63.731 35.862 13.590 1.00 78.77 C +ATOM 18764 CG GLU J 221 62.368 35.607 12.960 1.00 82.13 C +ATOM 18765 CD GLU J 221 61.808 36.784 12.164 1.00 78.52 C +ATOM 18766 OE1 GLU J 221 62.076 37.968 12.499 1.00 52.99 O +ATOM 18767 OE2 GLU J 221 61.189 36.501 11.107 1.00 98.45 O +ATOM 18768 N THR J 222 65.971 36.065 15.637 1.00121.41 N +ATOM 18769 CA THR J 222 67.359 36.280 16.056 1.00116.56 C +ATOM 18770 C THR J 222 67.853 35.125 16.922 1.00107.91 C +ATOM 18771 O THR J 222 68.947 34.593 16.709 1.00 80.51 O +ATOM 18772 CB THR J 222 67.468 37.591 16.857 1.00110.43 C +ATOM 18773 OG1 THR J 222 67.307 38.720 15.985 1.00 96.64 O +ATOM 18774 CG2 THR J 222 68.817 37.665 17.612 1.00123.05 C +ATOM 18775 N GLY J 223 67.034 34.757 17.904 1.00112.82 N +ATOM 18776 CA GLY J 223 67.333 33.626 18.775 1.00126.01 C +ATOM 18777 C GLY J 223 67.550 32.336 17.995 1.00123.85 C +ATOM 18778 O GLY J 223 68.437 31.536 18.333 1.00 80.53 O +ATOM 18779 N VAL J 224 66.730 32.116 16.965 1.00114.91 N +ATOM 18780 CA VAL J 224 66.823 30.887 16.186 1.00120.97 C +ATOM 18781 C VAL J 224 68.160 30.855 15.470 1.00134.46 C +ATOM 18782 O VAL J 224 68.827 29.819 15.422 1.00136.96 O +ATOM 18783 CB VAL J 224 65.692 30.767 15.161 1.00114.49 C +ATOM 18784 CG1 VAL J 224 65.944 29.581 14.238 1.00106.38 C +ATOM 18785 CG2 VAL J 224 64.351 30.623 15.867 1.00126.07 C +ATOM 18786 N ILE J 225 68.577 32.006 14.953 1.00134.10 N +ATOM 18787 CA ILE J 225 69.871 32.088 14.278 1.00129.41 C +ATOM 18788 C ILE J 225 70.996 31.737 15.247 1.00114.96 C +ATOM 18789 O ILE J 225 71.824 30.882 14.930 1.00 80.49 O +ATOM 18790 CB ILE J 225 70.119 33.480 13.655 1.00127.49 C +ATOM 18791 CG1 ILE J 225 69.161 33.714 12.488 1.00127.85 C +ATOM 18792 CG2 ILE J 225 71.550 33.591 13.144 1.00123.19 C +ATOM 18793 CD1 ILE J 225 69.021 35.170 12.093 1.00130.31 C +ATOM 18794 N PHE J 226 71.017 32.396 16.413 1.00 91.81 N +ATOM 18795 CA PHE J 226 72.053 32.149 17.417 1.00 99.06 C +ATOM 18796 C PHE J 226 72.086 30.673 17.817 1.00116.36 C +ATOM 18797 O PHE J 226 73.144 30.125 18.128 1.00110.60 O +ATOM 18798 CB PHE J 226 71.845 33.019 18.662 1.00 96.26 C +ATOM 18799 CG PHE J 226 72.348 34.438 18.526 1.00 97.12 C +ATOM 18800 CD1 PHE J 226 73.705 34.695 18.329 1.00 99.69 C +ATOM 18801 CD2 PHE J 226 71.486 35.525 18.722 1.00 96.07 C +ATOM 18802 CE1 PHE J 226 74.175 36.003 18.224 1.00 98.10 C +ATOM 18803 CE2 PHE J 226 71.955 36.828 18.658 1.00 99.15 C +ATOM 18804 CZ PHE J 226 73.297 37.068 18.378 1.00109.02 C +ATOM 18805 N LEU J 227 70.922 30.036 17.820 1.00129.01 N +ATOM 18806 CA LEU J 227 70.832 28.610 18.133 1.00133.99 C +ATOM 18807 C LEU J 227 71.474 27.750 17.059 1.00116.80 C +ATOM 18808 O LEU J 227 72.218 26.832 17.370 1.00 82.55 O +ATOM 18809 CB LEU J 227 69.366 28.223 18.306 1.00136.97 C +ATOM 18810 CG LEU J 227 68.708 28.612 19.641 1.00125.78 C +ATOM 18811 CD1 LEU J 227 67.204 28.481 19.676 1.00124.81 C +ATOM 18812 CD2 LEU J 227 69.299 27.834 20.797 1.00125.03 C +ATOM 18813 N ILE J 228 71.213 28.083 15.798 1.00132.87 N +ATOM 18814 CA ILE J 228 71.774 27.331 14.681 1.00130.66 C +ATOM 18815 C ILE J 228 73.282 27.497 14.666 1.00127.84 C +ATOM 18816 O ILE J 228 74.021 26.511 14.553 1.00119.18 O +ATOM 18817 CB ILE J 228 71.216 27.782 13.311 1.00129.21 C +ATOM 18818 CG1 ILE J 228 69.711 27.512 13.224 1.00126.96 C +ATOM 18819 CG2 ILE J 228 71.910 27.027 12.186 1.00113.99 C +ATOM 18820 CD1 ILE J 228 69.009 28.236 12.097 1.00106.34 C +ATOM 18821 N ASN J 229 73.737 28.742 14.794 1.00121.84 N +ATOM 18822 CA ASN J 229 75.170 29.043 14.785 1.00140.79 C +ATOM 18823 C ASN J 229 75.894 28.333 15.935 1.00138.84 C +ATOM 18824 O ASN J 229 76.936 27.697 15.736 1.00 78.65 O +ATOM 18825 CB ASN J 229 75.386 30.557 14.874 1.00135.66 C +ATOM 18826 CG ASN J 229 76.784 30.980 14.460 1.00176.12 C +ATOM 18827 OD1 ASN J 229 77.484 30.259 13.740 1.00224.24 O +ATOM 18828 ND2 ASN J 229 77.206 32.146 14.935 1.00172.34 N +ATOM 18829 N ASP J 230 75.278 28.374 17.113 1.00148.57 N +ATOM 18830 CA ASP J 230 75.806 27.690 18.279 1.00156.24 C +ATOM 18831 C ASP J 230 75.899 26.181 18.028 1.00179.03 C +ATOM 18832 O ASP J 230 76.871 25.529 18.412 1.00175.28 O +ATOM 18833 CB ASP J 230 74.925 27.976 19.494 1.00148.58 C +ATOM 18834 CG ASP J 230 75.510 27.422 20.775 1.00194.70 C +ATOM 18835 OD1 ASP J 230 76.515 27.984 21.250 1.00238.54 O +ATOM 18836 OD2 ASP J 230 74.994 26.414 21.305 1.00239.85 O +ATOM 18837 N GLY J 231 74.866 25.622 17.407 1.00194.03 N +ATOM 18838 CA GLY J 231 74.832 24.191 17.122 1.00198.36 C +ATOM 18839 C GLY J 231 75.882 23.784 16.102 1.00183.37 C +ATOM 18840 O GLY J 231 76.453 22.686 16.177 1.00141.33 O +ATOM 18841 N ILE J 232 76.132 24.673 15.145 1.00178.94 N +ATOM 18842 CA ILE J 232 77.186 24.456 14.165 1.00168.36 C +ATOM 18843 C ILE J 232 78.513 24.344 14.892 1.00143.78 C +ATOM 18844 O ILE J 232 79.290 23.409 14.626 1.00144.34 O +ATOM 18845 CB ILE J 232 77.234 25.589 13.109 1.00172.30 C +ATOM 18846 CG1 ILE J 232 76.042 25.452 12.154 1.00172.58 C +ATOM 18847 CG2 ILE J 232 78.549 25.573 12.326 1.00182.91 C +ATOM 18848 CD1 ILE J 232 75.734 26.707 11.360 1.00165.66 C +ATOM 18849 N ASP J 233 78.786 25.317 15.765 1.00106.56 N +ATOM 18850 CA ASP J 233 80.040 25.349 16.508 1.00130.90 C +ATOM 18851 C ASP J 233 80.201 24.070 17.315 1.00129.16 C +ATOM 18852 O ASP J 233 81.271 23.433 17.299 1.00174.42 O +ATOM 18853 CB ASP J 233 80.088 26.563 17.446 1.00143.53 C +ATOM 18854 CG ASP J 233 80.124 27.906 16.701 1.00133.72 C +ATOM 18855 OD1 ASP J 233 79.997 27.917 15.465 1.00 96.42 O +ATOM 18856 OD2 ASP J 233 80.388 28.940 17.366 1.00141.18 O +ATOM 18857 N ARG J 234 79.144 23.689 18.014 1.00122.65 N +ATOM 18858 CA ARG J 234 79.219 22.568 18.953 1.00166.13 C +ATOM 18859 C ARG J 234 79.053 21.181 18.311 1.00152.34 C +ATOM 18860 O ARG J 234 79.142 20.157 19.007 1.00125.47 O +ATOM 18861 CB ARG J 234 78.182 22.750 20.058 1.00171.70 C +ATOM 18862 CG ARG J 234 78.562 23.845 21.026 1.00169.33 C +ATOM 18863 CD ARG J 234 77.360 24.380 21.777 1.00154.79 C +ATOM 18864 NE ARG J 234 77.777 25.475 22.633 1.00180.27 N +ATOM 18865 CZ ARG J 234 77.635 25.487 23.953 1.00172.63 C +ATOM 18866 NH1 ARG J 234 76.962 24.513 24.568 1.00113.65 N +ATOM 18867 NH2 ARG J 234 78.133 26.513 24.656 1.00214.42 N +ATOM 18868 N GLY J 235 78.848 21.149 16.998 1.00117.70 N +ATOM 18869 CA GLY J 235 78.807 19.894 16.276 1.00113.34 C +ATOM 18870 C GLY J 235 77.500 19.164 16.471 1.00115.37 C +ATOM 18871 O GLY J 235 77.463 17.928 16.458 1.00 98.82 O +ATOM 18872 N LEU J 236 76.410 19.915 16.631 1.00141.27 N +ATOM 18873 CA LEU J 236 75.060 19.307 16.582 1.00142.32 C +ATOM 18874 C LEU J 236 74.722 18.981 15.133 1.00140.03 C +ATOM 18875 O LEU J 236 74.292 17.871 14.822 1.00119.54 O +ATOM 18876 CB LEU J 236 73.976 20.231 17.164 1.00117.31 C +ATOM 18877 CG LEU J 236 73.772 20.230 18.676 1.00 90.25 C +ATOM 18878 CD1 LEU J 236 74.858 21.063 19.364 1.00109.10 C +ATOM 18879 CD2 LEU J 236 72.405 20.785 19.022 1.00 81.96 C +ATOM 18880 N TRP J 237 74.949 19.951 14.252 1.00134.04 N +ATOM 18881 CA TRP J 237 74.635 19.797 12.839 1.00144.86 C +ATOM 18882 C TRP J 237 75.729 20.425 11.975 1.00178.45 C +ATOM 18883 O TRP J 237 76.559 21.190 12.477 1.00193.09 O +ATOM 18884 CB TRP J 237 73.270 20.416 12.535 1.00121.50 C +ATOM 18885 CG TRP J 237 72.972 21.600 13.374 1.00117.92 C +ATOM 18886 CD1 TRP J 237 73.599 22.805 13.328 1.00143.00 C +ATOM 18887 CD2 TRP J 237 71.977 21.705 14.402 1.00140.01 C +ATOM 18888 NE1 TRP J 237 73.055 23.661 14.257 1.00165.35 N +ATOM 18889 CE2 TRP J 237 72.039 23.020 14.912 1.00157.17 C +ATOM 18890 CE3 TRP J 237 71.033 20.826 14.931 1.00148.98 C +ATOM 18891 CZ2 TRP J 237 71.187 23.478 15.926 1.00141.22 C +ATOM 18892 CZ3 TRP J 237 70.202 21.280 15.956 1.00142.34 C +ATOM 18893 CH2 TRP J 237 70.291 22.590 16.440 1.00130.32 C +ATOM 18894 N ASP J 238 75.734 20.086 10.684 1.00191.72 N +ATOM 18895 CA ASP J 238 76.823 20.477 9.781 1.00169.76 C +ATOM 18896 C ASP J 238 76.329 21.147 8.503 1.00171.47 C +ATOM 18897 O ASP J 238 75.255 20.811 7.980 1.00162.51 O +ATOM 18898 CB ASP J 238 77.688 19.271 9.415 1.00123.32 C +ATOM 18899 CG ASP J 238 78.252 18.566 10.630 1.00127.51 C +ATOM 18900 OD1 ASP J 238 77.507 17.795 11.259 1.00123.82 O +ATOM 18901 OD2 ASP J 238 79.433 18.794 10.982 1.00142.86 O +ATOM 18902 N LEU J 239 77.139 22.076 7.996 1.00147.60 N +ATOM 18903 CA LEU J 239 76.806 22.807 6.785 1.00167.13 C +ATOM 18904 C LEU J 239 77.017 21.924 5.562 1.00189.73 C +ATOM 18905 O LEU J 239 77.953 21.116 5.517 1.00187.24 O +ATOM 18906 CB LEU J 239 77.663 24.075 6.663 1.00164.27 C +ATOM 18907 CG LEU J 239 77.322 25.298 7.511 1.00153.65 C +ATOM 18908 CD1 LEU J 239 78.223 26.471 7.160 1.00164.87 C +ATOM 18909 CD2 LEU J 239 75.873 25.695 7.326 1.00135.90 C +ATOM 18910 N GLN J 240 76.151 22.101 4.567 1.00183.01 N +ATOM 18911 CA GLN J 240 76.368 21.516 3.248 1.00176.59 C +ATOM 18912 C GLN J 240 77.753 21.882 2.710 1.00195.53 C +ATOM 18913 O GLN J 240 78.577 21.008 2.407 1.00148.21 O +ATOM 18914 CB GLN J 240 75.282 21.992 2.267 1.00157.00 C +ATOM 18915 CG GLN J 240 75.302 21.265 0.927 1.00149.77 C +ATOM 18916 CD GLN J 240 74.973 19.786 1.070 1.00159.17 C +ATOM 18917 OE1 GLN J 240 73.803 19.408 1.187 1.00175.37 O +ATOM 18918 NE2 GLN J 240 76.007 18.943 1.115 1.00144.51 N +ATOM 18919 N ASN J 241 78.001 23.183 2.622 1.00211.52 N +ATOM 18920 CA ASN J 241 79.274 23.707 2.174 1.00184.38 C +ATOM 18921 C ASN J 241 80.095 24.223 3.338 1.00162.87 C +ATOM 18922 O ASN J 241 79.792 25.289 3.895 1.00134.60 O +ATOM 18923 CB ASN J 241 79.042 24.836 1.182 1.00182.81 C +ATOM 18924 CG ASN J 241 79.210 24.373 -0.242 1.00235.78 C +ATOM 18925 OD1 ASN J 241 80.223 24.680 -0.880 1.00500.00 O +ATOM 18926 ND2 ASN J 241 78.207 23.675 -0.772 1.00293.05 N +ATOM 18927 N LYS J 242 81.188 23.521 3.637 1.00133.00 N +ATOM 18928 CA LYS J 242 82.091 23.944 4.709 1.00119.31 C +ATOM 18929 C LYS J 242 82.742 25.288 4.377 1.00128.82 C +ATOM 18930 O LYS J 242 83.092 26.068 5.263 1.00 90.46 O +ATOM 18931 CB LYS J 242 83.153 22.873 4.967 1.00111.18 C +ATOM 18932 CG LYS J 242 82.582 21.468 5.093 1.00125.30 C +ATOM 18933 CD LYS J 242 83.003 20.799 6.395 1.00126.04 C +ATOM 18934 CE LYS J 242 81.808 20.141 7.076 1.00146.76 C +ATOM 18935 NZ LYS J 242 82.198 19.341 8.266 1.00138.23 N +ATOM 18936 N ALA J 243 82.858 25.552 3.075 1.00197.71 N +ATOM 18937 CA ALA J 243 83.318 26.837 2.547 1.00215.84 C +ATOM 18938 C ALA J 243 82.405 27.987 2.961 1.00182.84 C +ATOM 18939 O ALA J 243 82.809 29.152 2.876 1.00201.73 O +ATOM 18940 CB ALA J 243 83.419 26.772 1.023 1.00239.70 C +ATOM 18941 N GLU J 244 81.166 27.672 3.340 1.00142.90 N +ATOM 18942 CA GLU J 244 80.210 28.718 3.672 1.00167.43 C +ATOM 18943 C GLU J 244 80.228 29.048 5.156 1.00173.18 C +ATOM 18944 O GLU J 244 79.336 29.732 5.633 1.00123.83 O +ATOM 18945 CB GLU J 244 78.798 28.334 3.224 1.00181.51 C +ATOM 18946 CG GLU J 244 78.579 28.418 1.722 1.00176.88 C +ATOM 18947 CD GLU J 244 77.114 28.295 1.336 1.00181.59 C +ATOM 18948 OE1 GLU J 244 76.584 27.158 1.344 1.00172.57 O +ATOM 18949 OE2 GLU J 244 76.499 29.335 1.006 1.00150.52 O +ATOM 18950 N ARG J 245 81.214 28.528 5.888 1.00182.44 N +ATOM 18951 CA ARG J 245 81.366 28.867 7.304 1.00171.05 C +ATOM 18952 C ARG J 245 81.501 30.372 7.527 1.00167.68 C +ATOM 18953 O ARG J 245 81.020 30.891 8.529 1.00169.37 O +ATOM 18954 CB ARG J 245 82.568 28.169 7.929 1.00154.76 C +ATOM 18955 CG ARG J 245 82.659 28.358 9.443 1.00161.63 C +ATOM 18956 CD ARG J 245 83.813 27.569 10.082 1.00174.96 C +ATOM 18957 NE ARG J 245 83.348 26.304 10.652 1.00183.43 N +ATOM 18958 CZ ARG J 245 82.603 26.197 11.752 1.00189.12 C +ATOM 18959 NH1 ARG J 245 82.216 27.273 12.411 1.00173.32 N +ATOM 18960 NH2 ARG J 245 82.226 25.001 12.194 1.00208.25 N +ATOM 18961 N GLN J 246 82.184 31.063 6.617 1.00173.05 N +ATOM 18962 CA GLN J 246 82.449 32.498 6.792 1.00151.37 C +ATOM 18963 C GLN J 246 81.369 33.346 6.134 1.00133.45 C +ATOM 18964 O GLN J 246 81.607 34.502 5.782 1.00140.82 O +ATOM 18965 CB GLN J 246 83.842 32.876 6.257 1.00154.24 C +ATOM 18966 CG GLN J 246 84.999 32.369 7.103 1.00169.73 C +ATOM 18967 CD GLN J 246 85.246 30.883 6.917 1.00183.52 C +ATOM 18968 OE1 GLN J 246 85.267 30.385 5.788 1.00159.64 O +ATOM 18969 NE2 GLN J 246 85.463 30.172 8.021 1.00180.84 N +ATOM 18970 N ASN J 247 80.208 32.736 5.903 1.00101.49 N +ATOM 18971 CA ASN J 247 79.016 33.459 5.463 1.00116.13 C +ATOM 18972 C ASN J 247 78.896 34.791 6.216 1.00 99.25 C +ATOM 18973 O ASN J 247 79.068 34.823 7.441 1.00147.29 O +ATOM 18974 CB ASN J 247 77.783 32.569 5.725 1.00137.61 C +ATOM 18975 CG ASN J 247 76.610 32.882 4.826 1.00150.58 C +ATOM 18976 OD1 ASN J 247 75.614 33.479 5.264 1.00142.82 O +ATOM 18977 ND2 ASN J 247 76.734 32.515 3.555 1.00142.73 N +ATOM 18978 N ASP J 248 78.504 35.852 5.509 1.00114.09 N +ATOM 18979 CA ASP J 248 78.320 37.189 6.118 1.00157.48 C +ATOM 18980 C ASP J 248 77.429 37.164 7.372 1.00191.10 C +ATOM 18981 O ASP J 248 77.767 37.737 8.418 1.00204.75 O +ATOM 18982 CB ASP J 248 77.685 38.168 5.117 1.00156.02 C +ATOM 18983 CG ASP J 248 78.619 38.546 3.991 1.00170.56 C +ATOM 18984 OD1 ASP J 248 79.834 38.708 4.237 1.00214.32 O +ATOM 18985 OD2 ASP J 248 78.134 38.690 2.854 1.00160.03 O +ATOM 18986 N ILE J 249 76.287 36.492 7.250 1.00189.06 N +ATOM 18987 CA ILE J 249 75.309 36.417 8.325 1.00150.70 C +ATOM 18988 C ILE J 249 75.874 35.633 9.517 1.00143.17 C +ATOM 18989 O ILE J 249 75.858 36.106 10.661 1.00173.14 O +ATOM 18990 CB ILE J 249 74.012 35.752 7.826 1.00135.20 C +ATOM 18991 CG1 ILE J 249 73.375 36.592 6.716 1.00132.35 C +ATOM 18992 CG2 ILE J 249 73.026 35.599 8.969 1.00164.92 C +ATOM 18993 CD1 ILE J 249 72.401 35.830 5.843 1.00140.38 C +ATOM 18994 N LEU J 250 76.399 34.442 9.236 1.00115.91 N +ATOM 18995 CA LEU J 250 76.979 33.592 10.278 1.00124.15 C +ATOM 18996 C LEU J 250 78.113 34.258 11.072 1.00144.31 C +ATOM 18997 O LEU J 250 78.210 34.070 12.287 1.00184.82 O +ATOM 18998 CB LEU J 250 77.481 32.275 9.683 1.00125.43 C +ATOM 18999 CG LEU J 250 76.395 31.239 9.388 1.00139.07 C +ATOM 19000 CD1 LEU J 250 76.921 30.096 8.535 1.00167.36 C +ATOM 19001 CD2 LEU J 250 75.825 30.697 10.681 1.00151.30 C +ATOM 19002 N VAL J 251 78.969 35.018 10.387 1.00164.09 N +ATOM 19003 CA VAL J 251 80.070 35.725 11.056 1.00152.35 C +ATOM 19004 C VAL J 251 79.572 36.977 11.781 1.00177.31 C +ATOM 19005 O VAL J 251 80.189 37.420 12.756 1.00249.75 O +ATOM 19006 CB VAL J 251 81.196 36.122 10.086 1.00138.77 C +ATOM 19007 CG1 VAL J 251 81.702 34.899 9.334 1.00129.73 C +ATOM 19008 CG2 VAL J 251 80.737 37.219 9.123 1.00148.85 C +ATOM 19009 N LYS J 252 78.447 37.529 11.325 1.00141.64 N +ATOM 19010 CA LYS J 252 77.808 38.648 12.013 1.00129.27 C +ATOM 19011 C LYS J 252 77.278 38.220 13.402 1.00161.29 C +ATOM 19012 O LYS J 252 77.544 38.883 14.418 1.00151.66 O +ATOM 19013 CB LYS J 252 76.687 39.198 11.137 1.00112.40 C +ATOM 19014 CG LYS J 252 75.917 40.361 11.732 1.00118.08 C +ATOM 19015 CD LYS J 252 74.809 40.797 10.780 1.00130.53 C +ATOM 19016 CE LYS J 252 73.476 40.981 11.497 1.00137.66 C +ATOM 19017 NZ LYS J 252 72.330 41.154 10.558 1.00138.30 N +ATOM 19018 N TYR J 253 76.591 37.075 13.448 1.00169.97 N +ATOM 19019 CA TYR J 253 76.027 36.541 14.702 1.00127.12 C +ATOM 19020 C TYR J 253 77.097 35.888 15.565 1.00126.71 C +ATOM 19021 O TYR J 253 77.037 35.946 16.796 1.00172.00 O +ATOM 19022 CB TYR J 253 74.893 35.550 14.411 1.00 92.33 C +ATOM 19023 CG TYR J 253 73.652 36.254 13.903 1.00117.13 C +ATOM 19024 CD1 TYR J 253 72.754 36.862 14.784 1.00142.98 C +ATOM 19025 CD2 TYR J 253 73.425 36.416 12.544 1.00133.11 C +ATOM 19026 CE1 TYR J 253 71.634 37.538 14.315 1.00141.37 C +ATOM 19027 CE2 TYR J 253 72.317 37.117 12.071 1.00133.85 C +ATOM 19028 CZ TYR J 253 71.418 37.657 12.965 1.00129.60 C +ATOM 19029 OH TYR J 253 70.306 38.332 12.504 1.00131.62 O +ATOM 19030 N ARG J 254 78.089 35.289 14.917 1.00116.28 N +ATOM 19031 CA ARG J 254 79.300 34.850 15.609 1.00124.44 C +ATOM 19032 C ARG J 254 79.950 36.023 16.353 1.00123.16 C +ATOM 19033 O ARG J 254 80.455 35.864 17.464 1.00113.27 O +ATOM 19034 CB ARG J 254 80.303 34.240 14.615 1.00140.79 C +ATOM 19035 CG ARG J 254 81.523 33.629 15.282 1.00141.84 C +ATOM 19036 CD ARG J 254 82.270 32.681 14.367 1.00159.80 C +ATOM 19037 NE ARG J 254 81.497 31.486 14.018 1.00166.58 N +ATOM 19038 CZ ARG J 254 80.977 31.228 12.818 1.00160.63 C +ATOM 19039 NH1 ARG J 254 81.112 32.089 11.816 1.00171.94 N +ATOM 19040 NH2 ARG J 254 80.318 30.090 12.615 1.00127.62 N +ATOM 19041 N HIS J 255 79.969 37.189 15.708 1.00129.90 N +ATOM 19042 CA HIS J 255 80.596 38.385 16.272 1.00150.31 C +ATOM 19043 C HIS J 255 79.817 38.929 17.452 1.00137.10 C +ATOM 19044 O HIS J 255 80.412 39.462 18.390 1.00172.93 O +ATOM 19045 CB HIS J 255 80.776 39.481 15.198 1.00175.29 C +ATOM 19046 CG HIS J 255 82.198 39.666 14.761 1.00172.68 C +ATOM 19047 ND1 HIS J 255 82.850 38.763 13.947 1.00173.04 N +ATOM 19048 CD2 HIS J 255 83.102 40.632 15.052 1.00159.28 C +ATOM 19049 CE1 HIS J 255 84.091 39.171 13.749 1.00173.73 C +ATOM 19050 NE2 HIS J 255 84.270 40.301 14.411 1.00174.53 N +ATOM 19051 N MET J 256 78.496 38.818 17.401 1.00111.94 N +ATOM 19052 CA MET J 256 77.685 39.303 18.510 1.00122.04 C +ATOM 19053 C MET J 256 77.923 38.464 19.777 1.00145.21 C +ATOM 19054 O MET J 256 77.720 38.952 20.904 1.00152.75 O +ATOM 19055 CB MET J 256 76.209 39.340 18.118 1.00136.53 C +ATOM 19056 CG MET J 256 75.937 40.125 16.837 1.00154.39 C +ATOM 19057 SD MET J 256 74.231 40.670 16.591 1.00158.65 S +ATOM 19058 CE MET J 256 74.103 41.921 17.887 1.00105.20 C +ATOM 19059 N SER J 257 78.404 37.229 19.592 1.00160.33 N +ATOM 19060 CA SER J 257 78.826 36.356 20.699 1.00139.61 C +ATOM 19061 C SER J 257 80.221 36.765 21.185 1.00127.66 C +ATOM 19062 O SER J 257 80.328 37.598 22.090 1.00135.43 O +ATOM 19063 CB SER J 257 78.823 34.878 20.268 1.00114.07 C +ATOM 19064 OG SER J 257 77.674 34.577 19.464 1.00112.44 O +TER 19065 SER J 257 +ATOM 19066 N LEU K 2 50.256 56.072 5.027 1.00155.14 N +ATOM 19067 CA LEU K 2 50.444 55.917 6.506 1.00147.52 C +ATOM 19068 C LEU K 2 49.180 55.320 7.150 1.00141.03 C +ATOM 19069 O LEU K 2 48.423 56.006 7.886 1.00 78.80 O +ATOM 19070 CB LEU K 2 50.829 57.254 7.162 1.00144.62 C +ATOM 19071 CG LEU K 2 52.144 57.938 6.732 1.00143.74 C +ATOM 19072 CD1 LEU K 2 52.305 59.243 7.500 1.00141.30 C +ATOM 19073 CD2 LEU K 2 53.401 57.077 6.893 1.00157.15 C +ATOM 19074 N THR K 3 48.897 54.082 6.729 1.00180.81 N +ATOM 19075 CA THR K 3 47.966 53.176 7.408 1.00202.52 C +ATOM 19076 C THR K 3 48.497 51.745 7.361 1.00180.65 C +ATOM 19077 O THR K 3 47.941 50.846 8.003 1.00190.70 O +ATOM 19078 CB THR K 3 46.559 53.151 6.779 1.00210.88 C +ATOM 19079 OG1 THR K 3 46.619 52.527 5.489 1.00227.20 O +ATOM 19080 CG2 THR K 3 45.974 54.560 6.688 1.00226.51 C +ATOM 19081 N ALA K 4 49.586 51.523 6.626 1.00162.04 N +ATOM 19082 CA ALA K 4 50.340 50.283 6.796 1.00164.48 C +ATOM 19083 C ALA K 4 51.271 50.392 8.035 1.00166.05 C +ATOM 19084 O ALA K 4 51.166 51.381 8.773 1.00148.02 O +ATOM 19085 CB ALA K 4 51.126 49.955 5.542 1.00127.20 C +ATOM 19086 N PRO K 5 52.106 49.356 8.321 1.00151.22 N +ATOM 19087 CA PRO K 5 52.693 49.413 9.651 1.00121.83 C +ATOM 19088 C PRO K 5 54.033 50.143 9.696 1.00139.23 C +ATOM 19089 O PRO K 5 54.605 50.470 8.654 1.00136.49 O +ATOM 19090 CB PRO K 5 52.904 47.943 9.998 1.00122.63 C +ATOM 19091 CG PRO K 5 53.092 47.237 8.690 1.00128.24 C +ATOM 19092 CD PRO K 5 52.482 48.108 7.616 1.00148.42 C +ATOM 19093 N PRO K 6 54.502 50.459 10.908 1.00137.54 N +ATOM 19094 CA PRO K 6 55.883 50.903 11.088 1.00130.84 C +ATOM 19095 C PRO K 6 56.871 49.733 11.129 1.00119.04 C +ATOM 19096 O PRO K 6 56.526 48.635 11.540 1.00105.93 O +ATOM 19097 CB PRO K 6 55.857 51.646 12.422 1.00113.55 C +ATOM 19098 CG PRO K 6 54.613 51.219 13.114 1.00103.35 C +ATOM 19099 CD PRO K 6 53.679 50.606 12.120 1.00113.26 C +ATOM 19100 N LYS K 7 58.088 49.968 10.668 1.00125.82 N +ATOM 19101 CA LYS K 7 59.114 48.920 10.636 1.00134.92 C +ATOM 19102 C LYS K 7 60.029 49.007 11.845 1.00134.08 C +ATOM 19103 O LYS K 7 60.001 49.990 12.591 1.00105.02 O +ATOM 19104 CB LYS K 7 59.928 48.972 9.329 1.00127.17 C +ATOM 19105 CG LYS K 7 59.153 48.560 8.096 1.00115.93 C +ATOM 19106 CD LYS K 7 58.712 49.737 7.241 1.00114.93 C +ATOM 19107 CE LYS K 7 58.192 49.255 5.903 1.00136.63 C +ATOM 19108 NZ LYS K 7 57.156 50.164 5.337 1.00149.24 N +ATOM 19109 N GLU K 8 60.856 47.981 12.016 1.00178.61 N +ATOM 19110 CA GLU K 8 61.613 47.793 13.251 1.00205.82 C +ATOM 19111 C GLU K 8 62.716 48.847 13.496 1.00195.25 C +ATOM 19112 O GLU K 8 63.620 49.016 12.701 1.00176.07 O +ATOM 19113 CB GLU K 8 62.133 46.365 13.336 1.00209.11 C +ATOM 19114 CG GLU K 8 61.280 45.513 14.324 1.00211.51 C +ATOM 19115 CD GLU K 8 60.348 44.500 13.650 1.00177.45 C +ATOM 19116 OE1 GLU K 8 59.713 44.896 12.649 1.00140.01 O +ATOM 19117 OE2 GLU K 8 60.194 43.346 14.160 1.00147.63 O +ATOM 19118 N ALA K 9 62.557 49.623 14.565 1.00187.02 N +ATOM 19119 CA ALA K 9 63.531 50.637 14.973 1.00141.33 C +ATOM 19120 C ALA K 9 64.442 50.074 16.062 1.00107.66 C +ATOM 19121 O ALA K 9 63.989 49.774 17.166 1.00109.87 O +ATOM 19122 CB ALA K 9 62.802 51.862 15.491 1.00140.56 C +ATOM 19123 N ALA K 10 65.719 49.937 15.734 1.00 91.83 N +ATOM 19124 CA ALA K 10 66.727 49.270 16.576 1.00 84.47 C +ATOM 19125 C ALA K 10 66.700 47.770 16.355 1.00 81.08 C +ATOM 19126 O ALA K 10 65.727 47.211 15.877 1.00 88.04 O +ATOM 19127 CB ALA K 10 66.582 49.615 18.052 1.00 79.52 C +ATOM 19128 N ARG K 11 67.830 47.134 16.620 1.00103.52 N +ATOM 19129 CA ARG K 11 68.086 45.759 16.162 1.00139.60 C +ATOM 19130 C ARG K 11 67.906 44.776 17.316 1.00125.21 C +ATOM 19131 O ARG K 11 68.171 45.128 18.472 1.00160.66 O +ATOM 19132 CB ARG K 11 69.535 45.658 15.660 1.00172.31 C +ATOM 19133 CG ARG K 11 70.499 45.844 16.851 1.00205.44 C +ATOM 19134 CD ARG K 11 71.589 46.860 16.631 1.00206.40 C +ATOM 19135 NE ARG K 11 71.737 47.747 17.805 1.00217.15 N +ATOM 19136 CZ ARG K 11 71.002 48.820 18.169 1.00181.61 C +ATOM 19137 NH1 ARG K 11 70.010 49.297 17.420 1.00184.42 N +ATOM 19138 NH2 ARG K 11 71.273 49.437 19.322 1.00127.54 N +ATOM 19139 N PRO K 12 67.542 43.526 17.007 1.00101.10 N +ATOM 19140 CA PRO K 12 67.727 42.515 18.016 1.00115.89 C +ATOM 19141 C PRO K 12 69.208 42.316 18.379 1.00112.27 C +ATOM 19142 O PRO K 12 69.998 41.866 17.553 1.00 87.98 O +ATOM 19143 CB PRO K 12 67.142 41.242 17.359 1.00117.04 C +ATOM 19144 CG PRO K 12 66.434 41.696 16.134 1.00 98.95 C +ATOM 19145 CD PRO K 12 67.135 42.945 15.722 1.00102.57 C +ATOM 19146 N THR K 13 69.558 42.652 19.618 1.00125.00 N +ATOM 19147 CA THR K 13 70.813 42.216 20.215 1.00140.04 C +ATOM 19148 C THR K 13 70.618 40.971 21.100 1.00130.40 C +ATOM 19149 O THR K 13 69.499 40.684 21.519 1.00180.49 O +ATOM 19150 CB THR K 13 71.385 43.336 21.082 1.00145.31 C +ATOM 19151 OG1 THR K 13 72.729 43.001 21.451 1.00182.82 O +ATOM 19152 CG2 THR K 13 70.504 43.590 22.350 1.00125.18 C +ATOM 19153 N LEU K 14 71.680 40.230 21.401 1.00105.45 N +ATOM 19154 CA LEU K 14 71.538 39.196 22.441 1.00112.90 C +ATOM 19155 C LEU K 14 71.537 39.886 23.803 1.00105.74 C +ATOM 19156 O LEU K 14 71.885 41.046 23.879 1.00 94.27 O +ATOM 19157 CB LEU K 14 72.571 38.078 22.337 1.00104.15 C +ATOM 19158 CG LEU K 14 74.028 38.455 22.276 1.00128.13 C +ATOM 19159 CD1 LEU K 14 74.878 37.396 22.953 1.00140.74 C +ATOM 19160 CD2 LEU K 14 74.434 38.588 20.825 1.00161.77 C +ATOM 19161 N MET K 15 71.003 39.248 24.840 1.00125.83 N +ATOM 19162 CA MET K 15 70.462 40.005 25.984 1.00127.48 C +ATOM 19163 C MET K 15 71.591 40.658 26.778 1.00110.54 C +ATOM 19164 O MET K 15 72.521 39.975 27.214 1.00 75.53 O +ATOM 19165 CB MET K 15 69.605 39.126 26.920 1.00146.46 C +ATOM 19166 CG MET K 15 68.522 39.909 27.671 1.00124.22 C +ATOM 19167 SD MET K 15 68.017 39.417 29.328 1.00128.23 S +ATOM 19168 CE MET K 15 69.424 38.496 29.995 1.00157.37 C +ATOM 19169 N PRO K 16 71.505 41.992 26.970 1.00107.18 N +ATOM 19170 CA PRO K 16 72.588 42.821 27.524 1.00 90.81 C +ATOM 19171 C PRO K 16 72.940 42.516 28.983 1.00 93.89 C +ATOM 19172 O PRO K 16 72.524 43.228 29.892 1.00 74.13 O +ATOM 19173 CB PRO K 16 72.046 44.252 27.375 1.00 88.89 C +ATOM 19174 CG PRO K 16 70.568 44.091 27.324 1.00103.72 C +ATOM 19175 CD PRO K 16 70.345 42.815 26.574 1.00104.66 C +ATOM 19176 N ARG K 17 73.762 41.489 29.182 1.00113.47 N +ATOM 19177 CA ARG K 17 74.310 41.161 30.503 1.00124.61 C +ATOM 19178 C ARG K 17 75.627 41.894 30.704 1.00115.12 C +ATOM 19179 O ARG K 17 76.341 42.142 29.741 1.00 97.37 O +ATOM 19180 CB ARG K 17 74.541 39.654 30.613 1.00148.55 C +ATOM 19181 CG ARG K 17 73.314 38.882 31.069 1.00144.56 C +ATOM 19182 CD ARG K 17 73.408 37.391 30.778 1.00136.43 C +ATOM 19183 NE ARG K 17 73.113 37.082 29.378 1.00141.18 N +ATOM 19184 CZ ARG K 17 73.282 35.885 28.831 1.00141.56 C +ATOM 19185 NH1 ARG K 17 73.714 34.880 29.587 1.00138.85 N +ATOM 19186 NH2 ARG K 17 72.994 35.683 27.550 1.00117.32 N +ATOM 19187 N ALA K 18 75.911 42.309 31.933 1.00129.24 N +ATOM 19188 CA ALA K 18 77.092 43.146 32.196 1.00134.41 C +ATOM 19189 C ALA K 18 78.130 42.419 33.065 1.00126.00 C +ATOM 19190 O ALA K 18 78.676 41.401 32.647 1.00 86.86 O +ATOM 19191 CB ALA K 18 76.702 44.499 32.804 1.00108.90 C +ATOM 19192 N GLN K 19 78.435 42.979 34.236 1.00108.37 N +ATOM 19193 CA GLN K 19 79.669 42.646 34.930 1.00 94.29 C +ATOM 19194 C GLN K 19 79.615 41.212 35.440 1.00 89.22 C +ATOM 19195 O GLN K 19 80.589 40.439 35.307 1.00111.00 O +ATOM 19196 CB GLN K 19 79.921 43.635 36.077 1.00 93.60 C +ATOM 19197 CG GLN K 19 81.263 43.466 36.786 1.00112.85 C +ATOM 19198 CD GLN K 19 82.445 43.509 35.830 1.00136.38 C +ATOM 19199 OE1 GLN K 19 82.726 44.539 35.215 1.00130.12 O +ATOM 19200 NE2 GLN K 19 83.127 42.376 35.680 1.00155.85 N +ATOM 19201 N SER K 20 78.522 40.910 36.132 1.00 72.20 N +ATOM 19202 CA SER K 20 78.283 39.596 36.684 1.00 63.26 C +ATOM 19203 C SER K 20 78.594 38.548 35.633 1.00 70.25 C +ATOM 19204 O SER K 20 79.317 37.560 35.905 1.00 60.14 O +ATOM 19205 CB SER K 20 76.826 39.514 37.130 1.00 54.11 C +ATOM 19206 OG SER K 20 76.506 40.582 38.018 1.00 44.35 O +ATOM 19207 N TYR K 21 78.084 38.785 34.428 1.00 80.30 N +ATOM 19208 CA TYR K 21 78.298 37.864 33.298 1.00137.75 C +ATOM 19209 C TYR K 21 79.792 37.676 32.986 1.00128.23 C +ATOM 19210 O TYR K 21 80.280 36.546 32.818 1.00 60.84 O +ATOM 19211 CB TYR K 21 77.557 38.388 32.053 1.00149.19 C +ATOM 19212 CG TYR K 21 77.679 37.507 30.827 1.00159.58 C +ATOM 19213 CD1 TYR K 21 76.931 36.339 30.704 1.00164.62 C +ATOM 19214 CD2 TYR K 21 78.550 37.832 29.802 1.00168.19 C +ATOM 19215 CE1 TYR K 21 77.064 35.515 29.607 1.00149.75 C +ATOM 19216 CE2 TYR K 21 78.678 37.007 28.695 1.00168.47 C +ATOM 19217 CZ TYR K 21 77.925 35.853 28.609 1.00136.51 C +ATOM 19218 OH TYR K 21 78.088 34.981 27.564 1.00166.54 O +ATOM 19219 N LYS K 22 80.500 38.797 32.888 1.00140.09 N +ATOM 19220 CA LYS K 22 81.915 38.785 32.521 1.00134.12 C +ATOM 19221 C LYS K 22 82.732 37.983 33.522 1.00129.94 C +ATOM 19222 O LYS K 22 83.667 37.274 33.147 1.00113.82 O +ATOM 19223 CB LYS K 22 82.450 40.224 32.419 1.00117.16 C +ATOM 19224 CG LYS K 22 82.282 40.865 31.049 1.00119.53 C +ATOM 19225 CD LYS K 22 83.524 40.887 30.189 1.00121.24 C +ATOM 19226 CE LYS K 22 83.083 40.836 28.726 1.00136.05 C +ATOM 19227 NZ LYS K 22 82.582 39.486 28.366 1.00154.70 N +ATOM 19228 N ASP K 23 82.411 38.162 34.802 1.00129.28 N +ATOM 19229 CA ASP K 23 83.061 37.409 35.876 1.00123.50 C +ATOM 19230 C ASP K 23 82.719 35.938 35.749 1.00105.09 C +ATOM 19231 O ASP K 23 83.599 35.071 35.862 1.00106.26 O +ATOM 19232 CB ASP K 23 82.600 37.917 37.247 1.00122.32 C +ATOM 19233 CG ASP K 23 83.113 39.302 37.562 1.00119.86 C +ATOM 19234 OD1 ASP K 23 84.286 39.568 37.238 1.00105.48 O +ATOM 19235 OD2 ASP K 23 82.326 40.114 38.100 1.00 91.24 O +ATOM 19236 N LEU K 24 81.439 35.668 35.500 1.00 86.76 N +ATOM 19237 CA LEU K 24 80.916 34.301 35.479 1.00 99.49 C +ATOM 19238 C LEU K 24 81.521 33.474 34.340 1.00111.13 C +ATOM 19239 O LEU K 24 81.763 32.250 34.489 1.00 76.19 O +ATOM 19240 CB LEU K 24 79.392 34.335 35.338 1.00104.81 C +ATOM 19241 CG LEU K 24 78.637 32.994 35.300 1.00114.17 C +ATOM 19242 CD1 LEU K 24 78.336 32.493 36.699 1.00126.25 C +ATOM 19243 CD2 LEU K 24 77.349 33.141 34.505 1.00118.99 C +ATOM 19244 N THR K 25 81.761 34.135 33.203 1.00117.31 N +ATOM 19245 CA THR K 25 82.292 33.452 32.019 1.00112.34 C +ATOM 19246 C THR K 25 83.785 33.130 32.161 1.00104.79 C +ATOM 19247 O THR K 25 84.217 31.997 31.884 1.00 61.68 O +ATOM 19248 CB THR K 25 82.058 34.285 30.744 1.00100.99 C +ATOM 19249 OG1 THR K 25 82.434 35.643 30.985 1.00 78.49 O +ATOM 19250 CG2 THR K 25 80.600 34.218 30.329 1.00 85.75 C +ATOM 19251 N HIS K 26 84.559 34.126 32.602 1.00125.87 N +ATOM 19252 CA HIS K 26 86.018 34.000 32.731 1.00134.72 C +ATOM 19253 C HIS K 26 86.421 33.341 34.062 1.00119.43 C +ATOM 19254 O HIS K 26 87.416 33.707 34.670 1.00121.20 O +ATOM 19255 CB HIS K 26 86.686 35.378 32.559 1.00130.55 C +ATOM 19256 CG HIS K 26 86.503 35.967 31.193 1.00144.73 C +ATOM 19257 ND1 HIS K 26 85.283 36.437 30.750 1.00162.07 N +ATOM 19258 CD2 HIS K 26 87.364 36.122 30.157 1.00133.32 C +ATOM 19259 CE1 HIS K 26 85.406 36.860 29.504 1.00152.41 C +ATOM 19260 NE2 HIS K 26 86.660 36.693 29.124 1.00135.73 N +ATOM 19261 N LEU K 27 85.631 32.375 34.516 1.00114.12 N +ATOM 19262 CA LEU K 27 85.971 31.624 35.716 1.00105.23 C +ATOM 19263 C LEU K 27 86.836 30.443 35.328 1.00 95.68 C +ATOM 19264 O LEU K 27 86.515 29.725 34.372 1.00109.91 O +ATOM 19265 CB LEU K 27 84.702 31.139 36.442 1.00108.63 C +ATOM 19266 CG LEU K 27 84.116 32.127 37.457 1.00119.70 C +ATOM 19267 CD1 LEU K 27 82.721 31.715 37.879 1.00105.96 C +ATOM 19268 CD2 LEU K 27 85.019 32.264 38.679 1.00128.48 C +ATOM 19269 N PRO K 28 87.925 30.212 36.081 1.00 81.38 N +ATOM 19270 CA PRO K 28 88.804 29.050 35.835 1.00 90.49 C +ATOM 19271 C PRO K 28 88.080 27.711 35.901 1.00 94.68 C +ATOM 19272 O PRO K 28 87.364 27.451 36.843 1.00 74.35 O +ATOM 19273 CB PRO K 28 89.822 29.128 36.968 1.00 95.03 C +ATOM 19274 CG PRO K 28 89.124 29.887 38.052 1.00 89.59 C +ATOM 19275 CD PRO K 28 88.243 30.878 37.351 1.00 77.49 C +ATOM 19276 N ALA K 29 88.230 26.891 34.870 1.00134.58 N +ATOM 19277 CA ALA K 29 87.373 25.716 34.694 1.00143.85 C +ATOM 19278 C ALA K 29 87.705 24.596 35.709 1.00116.73 C +ATOM 19279 O ALA K 29 88.852 24.447 36.137 1.00 71.45 O +ATOM 19280 CB ALA K 29 87.460 25.203 33.248 1.00164.47 C +ATOM 19281 N PRO K 30 86.688 23.809 36.093 1.00115.91 N +ATOM 19282 CA PRO K 30 86.866 22.663 36.987 1.00110.83 C +ATOM 19283 C PRO K 30 87.466 21.462 36.258 1.00 84.70 C +ATOM 19284 O PRO K 30 87.581 21.490 35.036 1.00 62.74 O +ATOM 19285 CB PRO K 30 85.432 22.351 37.426 1.00123.14 C +ATOM 19286 CG PRO K 30 84.583 22.789 36.280 1.00120.64 C +ATOM 19287 CD PRO K 30 85.287 23.957 35.649 1.00118.14 C +ATOM 19288 N THR K 31 87.732 20.383 36.994 1.00 93.59 N +ATOM 19289 CA THR K 31 88.284 19.146 36.404 1.00125.14 C +ATOM 19290 C THR K 31 87.306 18.431 35.459 1.00126.30 C +ATOM 19291 O THR K 31 87.722 17.739 34.538 1.00147.09 O +ATOM 19292 CB THR K 31 88.782 18.131 37.473 1.00131.92 C +ATOM 19293 OG1 THR K 31 87.748 17.842 38.419 1.00136.63 O +ATOM 19294 CG2 THR K 31 90.000 18.673 38.212 1.00142.30 C +ATOM 19295 N GLY K 32 86.013 18.601 35.701 1.00135.45 N +ATOM 19296 CA GLY K 32 84.979 18.203 34.752 1.00133.45 C +ATOM 19297 C GLY K 32 83.726 19.007 35.037 1.00142.66 C +ATOM 19298 O GLY K 32 83.559 19.503 36.155 1.00160.15 O +ATOM 19299 N LYS K 33 82.861 19.185 34.039 1.00133.24 N +ATOM 19300 CA LYS K 33 81.604 19.899 34.275 1.00133.75 C +ATOM 19301 C LYS K 33 80.666 19.075 35.163 1.00151.74 C +ATOM 19302 O LYS K 33 80.770 17.847 35.189 1.00139.55 O +ATOM 19303 CB LYS K 33 80.900 20.247 32.973 1.00112.13 C +ATOM 19304 CG LYS K 33 81.289 21.594 32.405 1.00111.71 C +ATOM 19305 CD LYS K 33 80.686 21.797 31.029 1.00116.03 C +ATOM 19306 CE LYS K 33 81.514 22.773 30.206 1.00118.13 C +ATOM 19307 NZ LYS K 33 81.037 22.853 28.801 1.00112.37 N +ATOM 19308 N ILE K 34 79.823 19.754 35.947 1.00152.63 N +ATOM 19309 CA ILE K 34 78.978 19.083 36.928 1.00136.37 C +ATOM 19310 C ILE K 34 77.539 19.132 36.419 1.00103.28 C +ATOM 19311 O ILE K 34 77.166 20.053 35.699 1.00 58.80 O +ATOM 19312 CB ILE K 34 79.136 19.697 38.349 1.00156.54 C +ATOM 19313 CG1 ILE K 34 80.544 19.432 38.904 1.00156.05 C +ATOM 19314 CG2 ILE K 34 78.144 19.098 39.339 1.00198.48 C +ATOM 19315 CD1 ILE K 34 81.332 20.694 39.175 1.00172.69 C +ATOM 19316 N PHE K 35 76.828 18.019 36.621 1.00113.06 N +ATOM 19317 CA PHE K 35 75.454 17.826 36.134 1.00105.03 C +ATOM 19318 C PHE K 35 74.496 18.434 37.127 1.00 95.35 C +ATOM 19319 O PHE K 35 74.514 18.076 38.299 1.00 83.80 O +ATOM 19320 CB PHE K 35 75.124 16.335 36.050 1.00105.89 C +ATOM 19321 CG PHE K 35 75.469 15.681 34.747 1.00 80.82 C +ATOM 19322 CD1 PHE K 35 75.111 16.251 33.542 1.00 61.73 C +ATOM 19323 CD2 PHE K 35 76.054 14.410 34.756 1.00 72.64 C +ATOM 19324 CE1 PHE K 35 75.508 15.650 32.367 1.00 68.56 C +ATOM 19325 CE2 PHE K 35 76.392 13.782 33.582 1.00 66.52 C +ATOM 19326 CZ PHE K 35 76.133 14.409 32.384 1.00 70.59 C +ATOM 19327 N VAL K 36 73.631 19.315 36.651 1.00 88.11 N +ATOM 19328 CA VAL K 36 72.786 20.047 37.561 1.00 84.42 C +ATOM 19329 C VAL K 36 71.331 20.034 37.096 1.00 72.55 C +ATOM 19330 O VAL K 36 71.052 20.047 35.895 1.00 91.15 O +ATOM 19331 CB VAL K 36 73.290 21.494 37.752 1.00 79.06 C +ATOM 19332 CG1 VAL K 36 72.958 22.349 36.538 1.00 97.96 C +ATOM 19333 CG2 VAL K 36 72.667 22.094 38.990 1.00 86.05 C +ATOM 19334 N SER K 37 70.408 20.080 38.052 1.00 52.12 N +ATOM 19335 CA SER K 37 69.003 20.178 37.744 1.00 44.36 C +ATOM 19336 C SER K 37 68.433 21.436 38.312 1.00 41.35 C +ATOM 19337 O SER K 37 68.612 21.722 39.488 1.00 47.22 O +ATOM 19338 CB SER K 37 68.304 18.998 38.362 1.00 40.35 C +ATOM 19339 OG SER K 37 68.570 17.806 37.638 1.00 45.66 O +ATOM 19340 N VAL K 38 67.661 22.163 37.530 1.00 38.17 N +ATOM 19341 CA VAL K 38 66.828 23.187 38.135 1.00 52.88 C +ATOM 19342 C VAL K 38 65.356 22.878 37.826 1.00 67.85 C +ATOM 19343 O VAL K 38 64.954 22.939 36.639 1.00105.11 O +ATOM 19344 CB VAL K 38 67.181 24.608 37.625 1.00 52.78 C +ATOM 19345 CG1 VAL K 38 66.239 25.650 38.224 1.00 55.81 C +ATOM 19346 CG2 VAL K 38 68.629 24.975 37.916 1.00 40.37 C +ATOM 19347 N TYR K 39 64.540 22.685 38.883 1.00 55.14 N +ATOM 19348 CA TYR K 39 63.097 22.449 38.731 1.00 51.61 C +ATOM 19349 C TYR K 39 62.257 23.752 38.717 1.00 71.96 C +ATOM 19350 O TYR K 39 61.524 24.034 37.755 1.00 75.27 O +ATOM 19351 CB TYR K 39 62.629 21.526 39.808 1.00 43.37 C +ATOM 19352 CG TYR K 39 62.866 20.087 39.444 1.00 44.45 C +ATOM 19353 CD1 TYR K 39 64.105 19.514 39.569 1.00 40.44 C +ATOM 19354 CD2 TYR K 39 61.813 19.271 39.021 1.00 53.30 C +ATOM 19355 CE1 TYR K 39 64.307 18.174 39.274 1.00 41.09 C +ATOM 19356 CE2 TYR K 39 62.003 17.912 38.769 1.00 54.62 C +ATOM 19357 CZ TYR K 39 63.267 17.373 38.905 1.00 43.39 C +ATOM 19358 OH TYR K 39 63.456 16.044 38.596 1.00 43.50 O +ATOM 19359 N ASN K 40 62.482 24.625 39.690 1.00 84.54 N +ATOM 19360 CA ASN K 40 61.752 25.888 39.730 1.00 79.77 C +ATOM 19361 C ASN K 40 62.316 26.886 40.748 1.00 87.11 C +ATOM 19362 O ASN K 40 62.557 26.546 41.911 1.00109.39 O +ATOM 19363 CB ASN K 40 60.290 25.610 40.056 1.00 81.85 C +ATOM 19364 CG ASN K 40 59.394 26.769 39.705 1.00117.48 C +ATOM 19365 OD1 ASN K 40 58.778 27.377 40.583 1.00139.81 O +ATOM 19366 ND2 ASN K 40 59.339 27.108 38.420 1.00125.47 N +ATOM 19367 N ILE K 41 62.471 28.134 40.322 1.00 85.36 N +ATOM 19368 CA ILE K 41 62.721 29.228 41.240 1.00 91.20 C +ATOM 19369 C ILE K 41 61.534 30.204 41.220 1.00 90.47 C +ATOM 19370 O ILE K 41 61.274 30.834 40.194 1.00117.28 O +ATOM 19371 CB ILE K 41 64.028 29.967 40.881 1.00 90.70 C +ATOM 19372 CG1 ILE K 41 65.252 29.207 41.405 1.00 92.99 C +ATOM 19373 CG2 ILE K 41 64.062 31.339 41.556 1.00121.85 C +ATOM 19374 CD1 ILE K 41 65.565 27.921 40.692 1.00 79.47 C +ATOM 19375 N GLN K 42 60.855 30.376 42.361 1.00 73.29 N +ATOM 19376 CA GLN K 42 59.573 31.098 42.396 1.00 75.56 C +ATOM 19377 C GLN K 42 59.730 32.579 42.680 1.00 70.52 C +ATOM 19378 O GLN K 42 60.737 33.011 43.242 1.00 75.84 O +ATOM 19379 CB GLN K 42 58.642 30.531 43.455 1.00 97.79 C +ATOM 19380 CG GLN K 42 58.187 29.108 43.205 1.00111.19 C +ATOM 19381 CD GLN K 42 58.629 28.153 44.312 1.00145.85 C +ATOM 19382 OE1 GLN K 42 57.939 28.003 45.328 1.00143.85 O +ATOM 19383 NE2 GLN K 42 59.820 27.563 44.160 1.00129.54 N +ATOM 19384 N ASP K 43 58.726 33.352 42.259 1.00 60.29 N +ATOM 19385 CA ASP K 43 58.629 34.766 42.602 1.00 55.63 C +ATOM 19386 C ASP K 43 58.033 34.917 43.982 1.00 55.89 C +ATOM 19387 O ASP K 43 56.914 35.380 44.131 1.00 40.98 O +ATOM 19388 CB ASP K 43 57.746 35.488 41.590 1.00 81.59 C +ATOM 19389 CG ASP K 43 57.753 37.014 41.786 1.00106.56 C +ATOM 19390 OD1 ASP K 43 58.854 37.593 41.863 1.00151.22 O +ATOM 19391 OD2 ASP K 43 56.671 37.654 41.796 1.00 89.90 O +ATOM 19392 N GLU K 44 58.765 34.456 45.002 1.00 89.25 N +ATOM 19393 CA GLU K 44 58.268 34.425 46.407 1.00 78.70 C +ATOM 19394 C GLU K 44 58.095 35.845 46.978 1.00 59.05 C +ATOM 19395 O GLU K 44 58.003 36.024 48.184 1.00 39.38 O +ATOM 19396 CB GLU K 44 59.194 33.537 47.297 1.00 67.34 C +ATOM 19397 CG GLU K 44 58.830 32.048 47.340 1.00 78.31 C +ATOM 19398 CD GLU K 44 59.786 31.179 48.195 1.00 83.71 C +ATOM 19399 OE1 GLU K 44 60.153 31.554 49.334 1.00 65.78 O +ATOM 19400 OE2 GLU K 44 60.115 30.053 47.765 1.00 86.08 O +ATOM 19401 N THR K 45 58.143 36.842 46.090 1.00 56.47 N +ATOM 19402 CA THR K 45 58.308 38.225 46.495 1.00 76.44 C +ATOM 19403 C THR K 45 56.999 38.753 47.066 1.00 73.53 C +ATOM 19404 O THR K 45 57.022 39.564 47.988 1.00 99.18 O +ATOM 19405 CB THR K 45 58.896 39.138 45.357 1.00 90.79 C +ATOM 19406 OG1 THR K 45 59.272 40.410 45.882 1.00 98.65 O +ATOM 19407 CG2 THR K 45 57.893 39.392 44.230 1.00 91.52 C +ATOM 19408 N GLY K 46 55.888 38.443 46.414 1.00 71.92 N +ATOM 19409 CA GLY K 46 54.557 38.888 46.872 1.00 91.21 C +ATOM 19410 C GLY K 46 54.065 40.248 46.356 1.00 88.70 C +ATOM 19411 O GLY K 46 53.210 40.925 46.943 1.00 83.84 O +ATOM 19412 N GLN K 47 54.650 40.705 45.277 1.00 83.07 N +ATOM 19413 CA GLN K 47 54.589 42.094 45.023 1.00 79.29 C +ATOM 19414 C GLN K 47 54.177 42.385 43.592 1.00 76.07 C +ATOM 19415 O GLN K 47 54.605 41.707 42.665 1.00 62.67 O +ATOM 19416 CB GLN K 47 55.924 42.705 45.366 1.00 74.13 C +ATOM 19417 CG GLN K 47 56.239 42.718 46.857 1.00 64.84 C +ATOM 19418 CD GLN K 47 55.122 43.288 47.711 1.00 73.69 C +ATOM 19419 OE1 GLN K 47 54.831 44.479 47.660 1.00 66.27 O +ATOM 19420 NE2 GLN K 47 54.457 42.439 48.465 1.00 87.43 N +ATOM 19421 N PHE K 48 53.322 43.394 43.453 1.00 77.68 N +ATOM 19422 CA PHE K 48 52.806 43.832 42.166 1.00 81.87 C +ATOM 19423 C PHE K 48 53.048 45.318 41.962 1.00116.66 C +ATOM 19424 O PHE K 48 53.370 46.056 42.916 1.00190.55 O +ATOM 19425 CB PHE K 48 51.290 43.579 42.069 1.00 78.64 C +ATOM 19426 CG PHE K 48 50.935 42.147 42.079 1.00 67.31 C +ATOM 19427 CD1 PHE K 48 51.016 41.433 43.235 1.00 67.44 C +ATOM 19428 CD2 PHE K 48 50.674 41.496 40.905 1.00 78.49 C +ATOM 19429 CE1 PHE K 48 50.829 40.087 43.240 1.00 80.96 C +ATOM 19430 CE2 PHE K 48 50.458 40.154 40.898 1.00 85.29 C +ATOM 19431 CZ PHE K 48 50.506 39.452 42.074 1.00 88.34 C +ATOM 19432 N LYS K 49 52.831 45.768 40.724 1.00101.62 N +ATOM 19433 CA LYS K 49 53.118 47.147 40.341 1.00 76.48 C +ATOM 19434 C LYS K 49 51.969 48.019 40.751 1.00 66.22 C +ATOM 19435 O LYS K 49 50.824 47.558 40.788 1.00 61.06 O +ATOM 19436 CB LYS K 49 53.384 47.259 38.842 1.00 78.21 C +ATOM 19437 CG LYS K 49 54.664 46.539 38.412 1.00 85.67 C +ATOM 19438 CD LYS K 49 55.130 46.772 36.985 1.00 96.82 C +ATOM 19439 CE LYS K 49 56.505 46.124 36.848 1.00101.55 C +ATOM 19440 NZ LYS K 49 57.171 46.290 35.526 1.00131.80 N +ATOM 19441 N PRO K 50 52.281 49.262 41.142 1.00 78.78 N +ATOM 19442 CA PRO K 50 51.268 50.228 41.593 1.00106.19 C +ATOM 19443 C PRO K 50 50.581 50.897 40.424 1.00122.52 C +ATOM 19444 O PRO K 50 51.008 50.742 39.261 1.00167.71 O +ATOM 19445 CB PRO K 50 52.075 51.269 42.385 1.00104.71 C +ATOM 19446 CG PRO K 50 53.435 51.206 41.778 1.00125.00 C +ATOM 19447 CD PRO K 50 53.649 49.774 41.337 1.00 98.39 C +ATOM 19448 N TYR K 51 49.506 51.623 40.717 1.00125.80 N +ATOM 19449 CA TYR K 51 48.846 52.423 39.692 1.00115.08 C +ATOM 19450 C TYR K 51 49.886 53.293 38.998 1.00142.50 C +ATOM 19451 O TYR K 51 50.754 53.858 39.670 1.00149.16 O +ATOM 19452 CB TYR K 51 47.771 53.310 40.301 1.00 84.48 C +ATOM 19453 CG TYR K 51 46.889 53.892 39.243 1.00103.03 C +ATOM 19454 CD1 TYR K 51 45.802 53.175 38.769 1.00131.89 C +ATOM 19455 CD2 TYR K 51 47.134 55.149 38.696 1.00130.21 C +ATOM 19456 CE1 TYR K 51 44.969 53.691 37.792 1.00168.42 C +ATOM 19457 CE2 TYR K 51 46.285 55.693 37.723 1.00168.36 C +ATOM 19458 CZ TYR K 51 45.227 54.931 37.248 1.00184.88 C +ATOM 19459 OH TYR K 51 44.360 55.393 36.275 1.00206.10 O +ATOM 19460 N PRO K 52 49.830 53.387 37.648 1.00146.93 N +ATOM 19461 CA PRO K 52 48.814 52.899 36.715 1.00124.88 C +ATOM 19462 C PRO K 52 49.044 51.541 36.081 1.00156.95 C +ATOM 19463 O PRO K 52 48.365 51.232 35.089 1.00223.46 O +ATOM 19464 CB PRO K 52 48.860 53.938 35.606 1.00131.98 C +ATOM 19465 CG PRO K 52 50.307 54.308 35.537 1.00153.09 C +ATOM 19466 CD PRO K 52 50.817 54.242 36.958 1.00167.55 C +ATOM 19467 N ALA K 53 49.920 50.710 36.651 1.00139.21 N +ATOM 19468 CA ALA K 53 50.069 49.350 36.136 1.00125.10 C +ATOM 19469 C ALA K 53 48.765 48.530 36.265 1.00119.45 C +ATOM 19470 O ALA K 53 47.862 48.865 37.072 1.00 63.26 O +ATOM 19471 CB ALA K 53 51.196 48.629 36.833 1.00114.16 C +ATOM 19472 N SER K 54 48.665 47.468 35.457 1.00117.05 N +ATOM 19473 CA SER K 54 47.615 46.488 35.672 1.00 95.77 C +ATOM 19474 C SER K 54 47.748 45.924 37.079 1.00114.64 C +ATOM 19475 O SER K 54 48.850 45.744 37.622 1.00130.38 O +ATOM 19476 CB SER K 54 47.654 45.353 34.661 1.00 59.47 C +ATOM 19477 OG SER K 54 46.992 44.206 35.161 1.00 46.75 O +ATOM 19478 N ASN K 55 46.597 45.726 37.711 1.00106.44 N +ATOM 19479 CA ASN K 55 46.533 45.148 39.045 1.00 83.18 C +ATOM 19480 C ASN K 55 47.366 43.881 39.142 1.00 77.71 C +ATOM 19481 O ASN K 55 47.936 43.542 40.206 1.00 87.02 O +ATOM 19482 CB ASN K 55 45.089 44.831 39.360 1.00 73.08 C +ATOM 19483 CG ASN K 55 44.867 44.577 40.814 1.00103.30 C +ATOM 19484 OD1 ASN K 55 45.656 44.958 41.680 1.00121.84 O +ATOM 19485 ND2 ASN K 55 43.758 43.953 41.098 1.00142.06 N +ATOM 19486 N PHE K 56 47.469 43.200 38.002 1.00 80.12 N +ATOM 19487 CA PHE K 56 48.042 41.856 37.941 1.00 79.58 C +ATOM 19488 C PHE K 56 49.499 41.875 37.512 1.00 94.88 C +ATOM 19489 O PHE K 56 50.102 40.811 37.320 1.00 91.18 O +ATOM 19490 CB PHE K 56 47.301 41.000 36.919 1.00 87.30 C +ATOM 19491 CG PHE K 56 45.856 40.834 37.199 1.00 88.97 C +ATOM 19492 CD1 PHE K 56 45.412 40.255 38.369 1.00 96.03 C +ATOM 19493 CD2 PHE K 56 44.937 41.292 36.295 1.00104.74 C +ATOM 19494 CE1 PHE K 56 44.062 40.171 38.652 1.00 99.09 C +ATOM 19495 CE2 PHE K 56 43.584 41.182 36.558 1.00111.89 C +ATOM 19496 CZ PHE K 56 43.147 40.623 37.743 1.00 95.28 C +ATOM 19497 N SER K 57 50.047 43.049 37.218 1.00 98.63 N +ATOM 19498 CA SER K 57 51.435 43.101 36.791 1.00108.50 C +ATOM 19499 C SER K 57 52.331 42.854 37.995 1.00 94.56 C +ATOM 19500 O SER K 57 52.385 43.655 38.944 1.00131.68 O +ATOM 19501 CB SER K 57 51.750 44.438 36.107 1.00157.27 C +ATOM 19502 OG SER K 57 51.190 44.462 34.802 1.00182.26 O +ATOM 19503 N THR K 58 53.034 41.739 37.967 1.00 79.82 N +ATOM 19504 CA THR K 58 53.982 41.452 39.019 1.00112.15 C +ATOM 19505 C THR K 58 55.162 42.404 39.031 1.00108.16 C +ATOM 19506 O THR K 58 55.609 42.907 38.012 1.00111.74 O +ATOM 19507 CB THR K 58 54.547 40.053 38.852 1.00126.97 C +ATOM 19508 OG1 THR K 58 55.258 39.971 37.617 1.00101.17 O +ATOM 19509 CG2 THR K 58 53.422 39.071 38.825 1.00139.33 C +ATOM 19510 N ALA K 59 55.739 42.595 40.190 1.00102.76 N +ATOM 19511 CA ALA K 59 56.832 43.526 40.244 1.00111.10 C +ATOM 19512 C ALA K 59 58.092 42.919 39.651 1.00 82.28 C +ATOM 19513 O ALA K 59 59.023 43.642 39.316 1.00 78.61 O +ATOM 19514 CB ALA K 59 57.062 43.989 41.666 1.00135.71 C +ATOM 19515 N VAL K 60 58.115 41.601 39.527 1.00 67.04 N +ATOM 19516 CA VAL K 60 59.326 40.902 39.182 1.00 78.56 C +ATOM 19517 C VAL K 60 58.971 39.858 38.161 1.00 68.69 C +ATOM 19518 O VAL K 60 57.936 39.211 38.279 1.00 74.65 O +ATOM 19519 CB VAL K 60 59.934 40.196 40.415 1.00 99.50 C +ATOM 19520 CG1 VAL K 60 61.196 39.409 40.062 1.00102.76 C +ATOM 19521 CG2 VAL K 60 60.248 41.201 41.519 1.00113.27 C +ATOM 19522 N PRO K 61 59.866 39.624 37.195 1.00 53.99 N +ATOM 19523 CA PRO K 61 59.505 38.691 36.146 1.00 61.12 C +ATOM 19524 C PRO K 61 59.514 37.272 36.682 1.00 67.73 C +ATOM 19525 O PRO K 61 60.321 36.954 37.567 1.00 41.33 O +ATOM 19526 CB PRO K 61 60.601 38.877 35.103 1.00 51.48 C +ATOM 19527 CG PRO K 61 61.708 39.526 35.839 1.00 46.88 C +ATOM 19528 CD PRO K 61 61.040 40.410 36.827 1.00 52.15 C +ATOM 19529 N GLN K 62 58.619 36.437 36.133 1.00 58.52 N +ATOM 19530 CA GLN K 62 58.422 35.094 36.640 1.00 56.69 C +ATOM 19531 C GLN K 62 59.339 34.153 35.924 1.00 47.90 C +ATOM 19532 O GLN K 62 58.990 33.007 35.704 1.00 78.39 O +ATOM 19533 CB GLN K 62 56.973 34.644 36.409 1.00 90.67 C +ATOM 19534 CG GLN K 62 55.900 35.617 36.892 1.00 89.74 C +ATOM 19535 CD GLN K 62 56.009 35.898 38.369 1.00 85.87 C +ATOM 19536 OE1 GLN K 62 55.628 35.082 39.204 1.00 80.23 O +ATOM 19537 NE2 GLN K 62 56.602 37.027 38.702 1.00105.47 N +ATOM 19538 N SER K 63 60.536 34.599 35.629 1.00 51.98 N +ATOM 19539 CA SER K 63 61.378 33.920 34.675 1.00 69.46 C +ATOM 19540 C SER K 63 62.719 33.495 35.283 1.00 88.16 C +ATOM 19541 O SER K 63 63.641 33.065 34.572 1.00 99.07 O +ATOM 19542 CB SER K 63 61.596 34.841 33.468 1.00 96.59 C +ATOM 19543 OG SER K 63 62.266 36.055 33.789 1.00 95.17 O +ATOM 19544 N ALA K 64 62.816 33.594 36.607 1.00 85.32 N +ATOM 19545 CA ALA K 64 64.076 33.380 37.308 1.00109.20 C +ATOM 19546 C ALA K 64 64.711 32.005 37.035 1.00 84.49 C +ATOM 19547 O ALA K 64 65.939 31.877 36.878 1.00108.33 O +ATOM 19548 CB ALA K 64 63.853 33.569 38.797 1.00118.09 C +ATOM 19549 N THR K 65 63.870 30.996 36.987 1.00 64.78 N +ATOM 19550 CA THR K 65 64.305 29.656 36.707 1.00 76.87 C +ATOM 19551 C THR K 65 65.217 29.589 35.489 1.00 71.14 C +ATOM 19552 O THR K 65 66.249 28.933 35.499 1.00 55.65 O +ATOM 19553 CB THR K 65 63.076 28.766 36.445 1.00108.72 C +ATOM 19554 OG1 THR K 65 62.018 29.163 37.331 1.00145.22 O +ATOM 19555 CG2 THR K 65 63.407 27.274 36.640 1.00 89.11 C +ATOM 19556 N ALA K 66 64.750 30.155 34.388 1.00104.93 N +ATOM 19557 CA ALA K 66 65.448 29.997 33.133 1.00120.14 C +ATOM 19558 C ALA K 66 66.751 30.783 33.215 1.00 90.21 C +ATOM 19559 O ALA K 66 67.753 30.404 32.579 1.00124.39 O +ATOM 19560 CB ALA K 66 64.555 30.453 31.973 1.00140.66 C +ATOM 19561 N MET K 67 66.704 31.917 33.917 1.00 63.36 N +ATOM 19562 CA MET K 67 67.891 32.768 34.050 1.00 84.29 C +ATOM 19563 C MET K 67 68.982 32.007 34.809 1.00 81.29 C +ATOM 19564 O MET K 67 70.163 32.044 34.459 1.00 56.80 O +ATOM 19565 CB MET K 67 67.558 34.066 34.789 1.00 88.35 C +ATOM 19566 CG MET K 67 66.720 35.075 34.022 1.00 83.36 C +ATOM 19567 SD MET K 67 66.123 36.384 35.116 1.00100.32 S +ATOM 19568 CE MET K 67 65.358 37.499 33.941 1.00122.93 C +ATOM 19569 N LEU K 68 68.562 31.284 35.837 1.00 82.91 N +ATOM 19570 CA LEU K 68 69.499 30.517 36.624 1.00 76.44 C +ATOM 19571 C LEU K 68 70.105 29.430 35.766 1.00 91.32 C +ATOM 19572 O LEU K 68 71.295 29.166 35.866 1.00 84.86 O +ATOM 19573 CB LEU K 68 68.823 29.885 37.845 1.00 89.76 C +ATOM 19574 CG LEU K 68 69.702 28.862 38.583 1.00 89.52 C +ATOM 19575 CD1 LEU K 68 70.906 29.547 39.205 1.00 87.89 C +ATOM 19576 CD2 LEU K 68 68.935 28.089 39.648 1.00 95.94 C +ATOM 19577 N VAL K 69 69.270 28.724 34.997 1.00102.88 N +ATOM 19578 CA VAL K 69 69.768 27.611 34.185 1.00 90.20 C +ATOM 19579 C VAL K 69 70.815 28.170 33.233 1.00 86.53 C +ATOM 19580 O VAL K 69 71.862 27.561 32.997 1.00 80.99 O +ATOM 19581 CB VAL K 69 68.644 26.903 33.392 1.00 66.61 C +ATOM 19582 CG1 VAL K 69 69.250 25.897 32.420 1.00 64.62 C +ATOM 19583 CG2 VAL K 69 67.682 26.167 34.311 1.00 83.74 C +ATOM 19584 N THR K 70 70.496 29.319 32.654 1.00 68.55 N +ATOM 19585 CA THR K 70 71.360 29.923 31.667 1.00 65.77 C +ATOM 19586 C THR K 70 72.669 30.282 32.337 1.00 78.41 C +ATOM 19587 O THR K 70 73.754 30.109 31.752 1.00 86.56 O +ATOM 19588 CB THR K 70 70.672 31.152 31.034 1.00 66.30 C +ATOM 19589 OG1 THR K 70 69.429 30.737 30.450 1.00 88.51 O +ATOM 19590 CG2 THR K 70 71.549 31.781 29.949 1.00 77.84 C +ATOM 19591 N ALA K 71 72.575 30.897 33.515 1.00 84.92 N +ATOM 19592 CA ALA K 71 73.788 31.327 34.225 1.00100.73 C +ATOM 19593 C ALA K 71 74.650 30.098 34.558 1.00100.71 C +ATOM 19594 O ALA K 71 75.878 30.131 34.454 1.00 59.01 O +ATOM 19595 CB ALA K 71 73.419 32.101 35.485 1.00102.20 C +ATOM 19596 N LEU K 72 73.989 29.014 34.959 1.00120.40 N +ATOM 19597 CA LEU K 72 74.691 27.773 35.292 1.00135.69 C +ATOM 19598 C LEU K 72 75.407 27.222 34.074 1.00165.39 C +ATOM 19599 O LEU K 72 76.403 26.518 34.208 1.00152.18 O +ATOM 19600 CB LEU K 72 73.717 26.721 35.826 1.00119.47 C +ATOM 19601 CG LEU K 72 73.119 27.016 37.196 1.00 96.85 C +ATOM 19602 CD1 LEU K 72 71.897 26.144 37.408 1.00 77.25 C +ATOM 19603 CD2 LEU K 72 74.130 26.795 38.311 1.00100.90 C +ATOM 19604 N LYS K 73 74.891 27.531 32.884 1.00164.46 N +ATOM 19605 CA LYS K 73 75.526 27.067 31.647 1.00145.53 C +ATOM 19606 C LYS K 73 76.670 27.960 31.219 1.00138.24 C +ATOM 19607 O LYS K 73 77.745 27.470 30.870 1.00115.35 O +ATOM 19608 CB LYS K 73 74.527 26.978 30.502 1.00126.48 C +ATOM 19609 CG LYS K 73 75.056 26.206 29.291 1.00113.76 C +ATOM 19610 CD LYS K 73 74.010 26.125 28.172 1.00129.99 C +ATOM 19611 CE LYS K 73 74.649 25.996 26.798 1.00156.58 C +ATOM 19612 NZ LYS K 73 74.384 24.687 26.137 1.00165.31 N +ATOM 19613 N ASP K 74 76.442 29.271 31.256 1.00139.10 N +ATOM 19614 CA ASP K 74 77.458 30.239 30.828 1.00139.72 C +ATOM 19615 C ASP K 74 78.749 30.133 31.651 1.00154.52 C +ATOM 19616 O ASP K 74 79.835 30.428 31.143 1.00148.46 O +ATOM 19617 CB ASP K 74 76.915 31.666 30.911 1.00111.38 C +ATOM 19618 CG ASP K 74 75.817 31.950 29.883 1.00111.48 C +ATOM 19619 OD1 ASP K 74 75.787 31.322 28.792 1.00 92.75 O +ATOM 19620 OD2 ASP K 74 74.959 32.819 30.185 1.00108.40 O +ATOM 19621 N SER K 75 78.624 29.687 32.907 1.00157.40 N +ATOM 19622 CA SER K 75 79.766 29.585 33.830 1.00139.62 C +ATOM 19623 C SER K 75 80.803 28.562 33.374 1.00114.09 C +ATOM 19624 O SER K 75 81.972 28.652 33.734 1.00 86.22 O +ATOM 19625 CB SER K 75 79.290 29.215 35.235 1.00145.79 C +ATOM 19626 OG SER K 75 79.160 27.810 35.379 1.00149.44 O +ATOM 19627 N ARG K 76 80.352 27.590 32.584 1.00138.09 N +ATOM 19628 CA ARG K 76 81.186 26.489 32.092 1.00140.14 C +ATOM 19629 C ARG K 76 81.701 25.663 33.247 1.00105.80 C +ATOM 19630 O ARG K 76 82.814 25.140 33.209 1.00 86.45 O +ATOM 19631 CB ARG K 76 82.341 26.997 31.234 1.00151.44 C +ATOM 19632 CG ARG K 76 81.923 27.758 29.975 1.00151.66 C +ATOM 19633 CD ARG K 76 83.153 28.184 29.180 1.00137.61 C +ATOM 19634 NE ARG K 76 83.916 29.221 29.868 1.00130.43 N +ATOM 19635 CZ ARG K 76 84.939 29.007 30.698 1.00135.08 C +ATOM 19636 NH1 ARG K 76 85.395 27.781 30.946 1.00137.09 N +ATOM 19637 NH2 ARG K 76 85.510 30.040 31.301 1.00132.00 N +ATOM 19638 N TRP K 77 80.848 25.521 34.255 1.00 94.84 N +ATOM 19639 CA TRP K 77 81.073 24.583 35.341 1.00105.49 C +ATOM 19640 C TRP K 77 80.021 23.462 35.344 1.00 99.86 C +ATOM 19641 O TRP K 77 80.309 22.320 35.730 1.00 68.80 O +ATOM 19642 CB TRP K 77 81.031 25.338 36.662 1.00114.97 C +ATOM 19643 CG TRP K 77 82.361 25.823 37.122 1.00121.41 C +ATOM 19644 CD1 TRP K 77 83.036 26.909 36.660 1.00142.15 C +ATOM 19645 CD2 TRP K 77 83.150 25.278 38.182 1.00102.11 C +ATOM 19646 NE1 TRP K 77 84.201 27.072 37.361 1.00137.16 N +ATOM 19647 CE2 TRP K 77 84.290 26.085 38.307 1.00105.66 C +ATOM 19648 CE3 TRP K 77 82.998 24.192 39.040 1.00 99.98 C +ATOM 19649 CZ2 TRP K 77 85.279 25.828 39.233 1.00 92.29 C +ATOM 19650 CZ3 TRP K 77 83.971 23.954 39.978 1.00108.16 C +ATOM 19651 CH2 TRP K 77 85.103 24.763 40.063 1.00103.07 C +ATOM 19652 N PHE K 78 78.803 23.811 34.932 1.00109.61 N +ATOM 19653 CA PHE K 78 77.653 22.912 35.004 1.00123.29 C +ATOM 19654 C PHE K 78 77.018 22.631 33.631 1.00139.23 C +ATOM 19655 O PHE K 78 76.936 23.510 32.782 1.00129.75 O +ATOM 19656 CB PHE K 78 76.582 23.545 35.863 1.00113.25 C +ATOM 19657 CG PHE K 78 77.058 23.944 37.202 1.00 96.69 C +ATOM 19658 CD1 PHE K 78 77.284 22.976 38.189 1.00101.65 C +ATOM 19659 CD2 PHE K 78 77.238 25.282 37.507 1.00 68.37 C +ATOM 19660 CE1 PHE K 78 77.731 23.337 39.451 1.00 95.79 C +ATOM 19661 CE2 PHE K 78 77.650 25.649 38.776 1.00 83.27 C +ATOM 19662 CZ PHE K 78 77.915 24.679 39.748 1.00 78.31 C +ATOM 19663 N ILE K 79 76.561 21.399 33.448 1.00126.49 N +ATOM 19664 CA ILE K 79 75.641 21.043 32.384 1.00 80.90 C +ATOM 19665 C ILE K 79 74.270 21.030 33.024 1.00 76.16 C +ATOM 19666 O ILE K 79 74.023 20.336 34.024 1.00 89.69 O +ATOM 19667 CB ILE K 79 75.917 19.619 31.875 1.00106.14 C +ATOM 19668 CG1 ILE K 79 77.411 19.427 31.573 1.00104.85 C +ATOM 19669 CG2 ILE K 79 75.082 19.307 30.636 1.00121.43 C +ATOM 19670 CD1 ILE K 79 77.876 17.977 31.604 1.00 93.61 C +ATOM 19671 N PRO K 80 73.383 21.850 32.515 1.00 78.96 N +ATOM 19672 CA PRO K 80 72.035 21.768 33.034 1.00 95.98 C +ATOM 19673 C PRO K 80 71.182 20.709 32.349 1.00 92.38 C +ATOM 19674 O PRO K 80 71.164 20.623 31.130 1.00 72.81 O +ATOM 19675 CB PRO K 80 71.476 23.176 32.772 1.00 83.63 C +ATOM 19676 CG PRO K 80 72.692 24.023 32.636 1.00 71.33 C +ATOM 19677 CD PRO K 80 73.624 23.137 31.875 1.00 77.28 C +ATOM 19678 N LEU K 81 70.493 19.906 33.154 1.00 93.26 N +ATOM 19679 CA LEU K 81 69.514 18.950 32.655 1.00 82.52 C +ATOM 19680 C LEU K 81 68.111 19.514 32.726 1.00 71.48 C +ATOM 19681 O LEU K 81 67.816 20.356 33.605 1.00 86.28 O +ATOM 19682 CB LEU K 81 69.586 17.696 33.473 1.00 91.52 C +ATOM 19683 CG LEU K 81 71.015 17.147 33.529 1.00139.23 C +ATOM 19684 CD1 LEU K 81 71.024 15.964 34.454 1.00138.82 C +ATOM 19685 CD2 LEU K 81 71.477 16.740 32.148 1.00175.65 C +ATOM 19686 N GLU K 82 67.344 19.227 31.680 1.00 71.23 N +ATOM 19687 CA GLU K 82 66.069 19.917 31.443 1.00101.93 C +ATOM 19688 C GLU K 82 65.020 19.247 32.288 1.00124.27 C +ATOM 19689 O GLU K 82 64.614 18.113 32.014 1.00160.56 O +ATOM 19690 CB GLU K 82 65.640 19.922 29.941 1.00111.27 C +ATOM 19691 CG GLU K 82 64.252 20.537 29.640 1.00 92.94 C +ATOM 19692 CD GLU K 82 64.164 22.069 29.809 1.00101.26 C +ATOM 19693 OE1 GLU K 82 64.636 22.637 30.857 1.00179.19 O +ATOM 19694 OE2 GLU K 82 63.604 22.728 28.904 1.00 53.73 O +ATOM 19695 N ARG K 83 64.559 19.995 33.284 1.00110.79 N +ATOM 19696 CA ARG K 83 63.459 19.565 34.120 1.00 80.61 C +ATOM 19697 C ARG K 83 62.308 20.571 34.127 1.00 69.85 C +ATOM 19698 O ARG K 83 61.194 20.224 34.486 1.00 94.72 O +ATOM 19699 CB ARG K 83 63.975 19.305 35.543 1.00 82.24 C +ATOM 19700 CG ARG K 83 65.102 18.287 35.633 1.00 65.80 C +ATOM 19701 CD ARG K 83 64.638 16.879 35.292 1.00 56.41 C +ATOM 19702 NE ARG K 83 65.685 15.937 35.639 1.00 54.16 N +ATOM 19703 CZ ARG K 83 66.556 15.415 34.792 1.00 59.91 C +ATOM 19704 NH1 ARG K 83 66.419 15.605 33.475 1.00 59.89 N +ATOM 19705 NH2 ARG K 83 67.589 14.696 35.264 1.00 54.58 N +ATOM 19706 N GLN K 84 62.546 21.834 33.787 1.00 77.23 N +ATOM 19707 CA GLN K 84 61.420 22.805 33.765 1.00 92.21 C +ATOM 19708 C GLN K 84 60.312 22.320 32.836 1.00 99.06 C +ATOM 19709 O GLN K 84 59.145 22.389 33.169 1.00 99.69 O +ATOM 19710 CB GLN K 84 61.860 24.228 33.374 1.00104.04 C +ATOM 19711 CG GLN K 84 61.038 25.339 34.007 1.00 97.16 C +ATOM 19712 CD GLN K 84 61.451 26.714 33.500 1.00129.39 C +ATOM 19713 OE1 GLN K 84 62.639 26.992 33.304 1.00182.34 O +ATOM 19714 NE2 GLN K 84 60.483 27.613 33.380 1.00152.03 N +ATOM 19715 N GLY K 85 60.674 21.756 31.695 1.00107.56 N +ATOM 19716 CA GLY K 85 59.649 21.254 30.802 1.00111.35 C +ATOM 19717 C GLY K 85 59.670 19.748 30.710 1.00105.62 C +ATOM 19718 O GLY K 85 59.448 19.198 29.629 1.00107.18 O +ATOM 19719 N LEU K 86 59.870 19.076 31.844 1.00100.72 N +ATOM 19720 CA LEU K 86 60.129 17.634 31.846 1.00106.53 C +ATOM 19721 C LEU K 86 58.990 16.841 31.189 1.00 92.97 C +ATOM 19722 O LEU K 86 59.236 15.850 30.497 1.00 89.84 O +ATOM 19723 CB LEU K 86 60.369 17.113 33.270 1.00 97.98 C +ATOM 19724 CG LEU K 86 60.493 15.605 33.515 1.00101.59 C +ATOM 19725 CD1 LEU K 86 61.655 14.983 32.754 1.00121.75 C +ATOM 19726 CD2 LEU K 86 60.656 15.343 35.004 1.00 98.93 C +ATOM 19727 N GLN K 87 57.767 17.324 31.341 1.00 81.22 N +ATOM 19728 CA GLN K 87 56.614 16.589 30.855 1.00101.19 C +ATOM 19729 C GLN K 87 56.654 16.443 29.326 1.00100.83 C +ATOM 19730 O GLN K 87 56.392 15.358 28.759 1.00 93.63 O +ATOM 19731 CB GLN K 87 55.319 17.268 31.332 1.00114.71 C +ATOM 19732 CG GLN K 87 54.168 16.297 31.612 1.00114.20 C +ATOM 19733 CD GLN K 87 54.586 15.035 32.376 1.00113.15 C +ATOM 19734 OE1 GLN K 87 55.172 15.109 33.463 1.00116.76 O +ATOM 19735 NE2 GLN K 87 54.313 13.869 31.792 1.00104.81 N +ATOM 19736 N ASN K 88 57.007 17.533 28.653 1.00 83.63 N +ATOM 19737 CA ASN K 88 57.102 17.519 27.192 1.00 79.95 C +ATOM 19738 C ASN K 88 58.191 16.573 26.708 1.00 79.63 C +ATOM 19739 O ASN K 88 58.113 15.972 25.621 1.00 55.33 O +ATOM 19740 CB ASN K 88 57.401 18.915 26.693 1.00 68.49 C +ATOM 19741 CG ASN K 88 56.398 19.893 27.183 1.00 75.15 C +ATOM 19742 OD1 ASN K 88 55.196 19.593 27.197 1.00 67.46 O +ATOM 19743 ND2 ASN K 88 56.848 21.107 27.498 1.00 97.01 N +ATOM 19744 N LEU K 89 59.258 16.522 27.491 1.00 73.88 N +ATOM 19745 CA LEU K 89 60.419 15.755 27.126 1.00 68.63 C +ATOM 19746 C LEU K 89 59.951 14.302 27.100 1.00 56.47 C +ATOM 19747 O LEU K 89 60.332 13.521 26.218 1.00 47.19 O +ATOM 19748 CB LEU K 89 61.554 16.055 28.138 1.00 73.02 C +ATOM 19749 CG LEU K 89 63.012 15.932 27.713 1.00 77.22 C +ATOM 19750 CD1 LEU K 89 63.666 14.799 28.486 1.00 92.20 C +ATOM 19751 CD2 LEU K 89 63.152 15.688 26.218 1.00 87.31 C +ATOM 19752 N LEU K 90 59.149 13.948 28.097 1.00 63.74 N +ATOM 19753 CA LEU K 90 58.765 12.550 28.289 1.00 70.50 C +ATOM 19754 C LEU K 90 57.759 12.178 27.224 1.00 70.28 C +ATOM 19755 O LEU K 90 57.695 11.028 26.775 1.00 62.19 O +ATOM 19756 CB LEU K 90 58.176 12.359 29.675 1.00 67.97 C +ATOM 19757 CG LEU K 90 59.125 12.651 30.834 1.00 68.85 C +ATOM 19758 CD1 LEU K 90 58.342 12.871 32.108 1.00 66.92 C +ATOM 19759 CD2 LEU K 90 60.093 11.483 30.972 1.00 93.02 C +ATOM 19760 N ASN K 91 57.005 13.181 26.784 1.00 71.71 N +ATOM 19761 CA ASN K 91 56.038 13.004 25.700 1.00 84.69 C +ATOM 19762 C ASN K 91 56.714 12.749 24.346 1.00 71.68 C +ATOM 19763 O ASN K 91 56.377 11.789 23.650 1.00 55.65 O +ATOM 19764 CB ASN K 91 55.169 14.252 25.607 1.00107.99 C +ATOM 19765 CG ASN K 91 53.712 14.011 25.882 1.00116.41 C +ATOM 19766 OD1 ASN K 91 53.320 13.060 26.563 1.00106.63 O +ATOM 19767 ND2 ASN K 91 52.900 14.945 25.404 1.00124.19 N +ATOM 19768 N GLU K 92 57.698 13.576 23.998 1.00 71.07 N +ATOM 19769 CA GLU K 92 58.485 13.331 22.773 1.00 70.20 C +ATOM 19770 C GLU K 92 59.151 11.952 22.781 1.00 58.19 C +ATOM 19771 O GLU K 92 59.242 11.277 21.755 1.00 53.83 O +ATOM 19772 CB GLU K 92 59.553 14.410 22.561 1.00 60.81 C +ATOM 19773 CG GLU K 92 59.080 15.586 21.721 1.00 65.00 C +ATOM 19774 CD GLU K 92 58.508 15.190 20.324 1.00 65.23 C +ATOM 19775 OE1 GLU K 92 59.160 14.519 19.526 1.00 55.47 O +ATOM 19776 OE2 GLU K 92 57.382 15.542 20.007 1.00 43.37 O +ATOM 19777 N ARG K 93 59.548 11.509 23.964 1.00 61.82 N +ATOM 19778 CA ARG K 93 60.148 10.195 24.112 1.00 75.30 C +ATOM 19779 C ARG K 93 59.120 9.064 23.965 1.00 77.42 C +ATOM 19780 O ARG K 93 59.405 8.029 23.356 1.00 64.33 O +ATOM 19781 CB ARG K 93 60.919 10.123 25.441 1.00 72.49 C +ATOM 19782 CG ARG K 93 62.171 11.023 25.424 1.00 57.31 C +ATOM 19783 CD ARG K 93 62.783 11.248 26.764 1.00 44.68 C +ATOM 19784 NE ARG K 93 63.950 10.376 26.928 1.00 43.14 N +ATOM 19785 CZ ARG K 93 63.944 9.206 27.560 1.00 53.49 C +ATOM 19786 NH1 ARG K 93 62.820 8.704 28.122 1.00 63.49 N +ATOM 19787 NH2 ARG K 93 65.081 8.558 27.716 1.00 62.32 N +ATOM 19788 N LYS K 94 57.891 9.319 24.381 1.00 94.96 N +ATOM 19789 CA LYS K 94 56.805 8.391 24.073 1.00107.55 C +ATOM 19790 C LYS K 94 56.608 8.258 22.561 1.00 90.90 C +ATOM 19791 O LYS K 94 56.349 7.156 22.050 1.00 73.15 O +ATOM 19792 CB LYS K 94 55.495 8.857 24.713 1.00120.34 C +ATOM 19793 CG LYS K 94 55.278 8.398 26.147 1.00138.07 C +ATOM 19794 CD LYS K 94 54.051 9.081 26.738 1.00140.00 C +ATOM 19795 CE LYS K 94 53.484 8.353 27.951 1.00132.77 C +ATOM 19796 NZ LYS K 94 52.538 9.236 28.687 1.00125.61 N +ATOM 19797 N ILE K 95 56.655 9.393 21.861 1.00 76.69 N +ATOM 19798 CA ILE K 95 56.340 9.406 20.428 1.00 74.52 C +ATOM 19799 C ILE K 95 57.421 8.703 19.634 1.00 64.26 C +ATOM 19800 O ILE K 95 57.129 7.987 18.668 1.00 53.31 O +ATOM 19801 CB ILE K 95 56.150 10.826 19.848 1.00 72.06 C +ATOM 19802 CG1 ILE K 95 55.209 11.653 20.715 1.00 66.74 C +ATOM 19803 CG2 ILE K 95 55.550 10.689 18.458 1.00 86.71 C +ATOM 19804 CD1 ILE K 95 54.704 12.909 20.057 1.00 72.49 C +ATOM 19805 N ILE K 96 58.662 8.966 20.044 1.00 65.92 N +ATOM 19806 CA ILE K 96 59.808 8.276 19.518 1.00 66.67 C +ATOM 19807 C ILE K 96 59.587 6.783 19.681 1.00 66.01 C +ATOM 19808 O ILE K 96 59.635 6.047 18.701 1.00 82.93 O +ATOM 19809 CB ILE K 96 61.125 8.681 20.225 1.00 81.14 C +ATOM 19810 CG1 ILE K 96 61.475 10.141 19.926 1.00 67.03 C +ATOM 19811 CG2 ILE K 96 62.267 7.799 19.739 1.00 80.11 C +ATOM 19812 CD1 ILE K 96 62.790 10.572 20.541 1.00 60.66 C +ATOM 19813 N ARG K 97 59.402 6.324 20.916 1.00 68.21 N +ATOM 19814 CA ARG K 97 59.341 4.875 21.190 1.00 88.27 C +ATOM 19815 C ARG K 97 58.182 4.232 20.427 1.00 99.78 C +ATOM 19816 O ARG K 97 58.249 3.053 20.039 1.00 81.96 O +ATOM 19817 CB ARG K 97 59.190 4.598 22.692 1.00 88.80 C +ATOM 19818 CG ARG K 97 60.449 4.105 23.378 1.00 87.88 C +ATOM 19819 CD ARG K 97 60.195 3.805 24.849 1.00100.38 C +ATOM 19820 NE ARG K 97 60.221 5.021 25.676 1.00115.22 N +ATOM 19821 CZ ARG K 97 61.269 5.438 26.394 1.00105.69 C +ATOM 19822 NH1 ARG K 97 62.418 4.748 26.399 1.00 80.06 N +ATOM 19823 NH2 ARG K 97 61.179 6.566 27.103 1.00105.61 N +ATOM 19824 N ALA K 98 57.123 5.007 20.208 1.00 85.27 N +ATOM 19825 CA ALA K 98 55.981 4.509 19.468 1.00 90.15 C +ATOM 19826 C ALA K 98 56.276 4.449 17.977 1.00 82.52 C +ATOM 19827 O ALA K 98 55.738 3.593 17.250 1.00 72.70 O +ATOM 19828 CB ALA K 98 54.786 5.389 19.731 1.00 99.76 C +ATOM 19829 N ALA K 99 57.188 5.314 17.543 1.00 85.69 N +ATOM 19830 CA ALA K 99 57.599 5.362 16.140 1.00 94.64 C +ATOM 19831 C ALA K 99 58.406 4.132 15.723 1.00 73.94 C +ATOM 19832 O ALA K 99 58.136 3.514 14.700 1.00 82.17 O +ATOM 19833 CB ALA K 99 58.402 6.635 15.867 1.00121.03 C +ATOM 19834 N GLN K 100 59.406 3.800 16.512 1.00 66.94 N +ATOM 19835 CA GLN K 100 60.458 2.918 16.043 1.00 92.50 C +ATOM 19836 C GLN K 100 60.397 1.537 16.653 1.00 97.03 C +ATOM 19837 O GLN K 100 61.319 0.731 16.467 1.00137.93 O +ATOM 19838 CB GLN K 100 61.857 3.554 16.261 1.00109.17 C +ATOM 19839 CG GLN K 100 62.059 4.260 17.592 1.00102.44 C +ATOM 19840 CD GLN K 100 63.097 5.382 17.532 1.00107.82 C +ATOM 19841 OE1 GLN K 100 62.971 6.366 16.765 1.00 66.25 O +ATOM 19842 NE2 GLN K 100 64.117 5.244 18.369 1.00 95.53 N +ATOM 19843 N GLU K 101 59.344 1.271 17.409 1.00 99.42 N +ATOM 19844 CA GLU K 101 59.238 -0.007 18.119 1.00113.64 C +ATOM 19845 C GLU K 101 59.056 -1.180 17.159 1.00113.22 C +ATOM 19846 O GLU K 101 59.365 -2.325 17.503 1.00 78.35 O +ATOM 19847 CB GLU K 101 58.101 0.033 19.144 1.00122.67 C +ATOM 19848 CG GLU K 101 56.764 0.509 18.589 1.00134.94 C +ATOM 19849 CD GLU K 101 55.644 0.428 19.617 1.00124.35 C +ATOM 19850 OE1 GLU K 101 55.959 0.363 20.822 1.00122.62 O +ATOM 19851 OE2 GLU K 101 54.454 0.497 19.229 1.00103.67 O +ATOM 19852 N ASN K 102 58.560 -0.904 15.956 1.00114.30 N +ATOM 19853 CA ASN K 102 58.296 -1.976 14.993 1.00141.57 C +ATOM 19854 C ASN K 102 59.465 -2.257 14.047 1.00172.07 C +ATOM 19855 O ASN K 102 59.370 -3.118 13.181 1.00160.05 O +ATOM 19856 CB ASN K 102 57.043 -1.648 14.189 1.00142.70 C +ATOM 19857 CG ASN K 102 55.796 -1.773 15.013 1.00134.19 C +ATOM 19858 OD1 ASN K 102 55.300 -2.882 15.258 1.00116.07 O +ATOM 19859 ND2 ASN K 102 55.304 -0.631 15.503 1.00133.91 N +ATOM 19860 N GLY K 103 60.532 -1.472 14.157 1.00180.28 N +ATOM 19861 CA GLY K 103 61.678 -1.611 13.250 1.00150.01 C +ATOM 19862 C GLY K 103 61.379 -1.396 11.772 1.00125.44 C +ATOM 19863 O GLY K 103 61.928 -2.069 10.906 1.00145.40 O +ATOM 19864 N THR K 104 60.442 -0.505 11.486 1.00145.08 N +ATOM 19865 CA THR K 104 60.199 -0.088 10.121 1.00150.87 C +ATOM 19866 C THR K 104 60.856 1.250 9.896 1.00137.37 C +ATOM 19867 O THR K 104 61.253 1.544 8.783 1.00114.65 O +ATOM 19868 CB THR K 104 58.685 -0.004 9.773 1.00165.42 C +ATOM 19869 OG1 THR K 104 58.035 1.006 10.556 1.00128.25 O +ATOM 19870 CG2 THR K 104 57.995 -1.358 10.001 1.00149.11 C +ATOM 19871 N VAL K 105 61.008 2.043 10.955 1.00160.34 N +ATOM 19872 CA VAL K 105 61.500 3.419 10.795 1.00190.14 C +ATOM 19873 C VAL K 105 62.886 3.432 10.144 1.00201.38 C +ATOM 19874 O VAL K 105 63.744 2.575 10.441 1.00132.12 O +ATOM 19875 CB VAL K 105 61.487 4.240 12.119 1.00190.21 C +ATOM 19876 CG1 VAL K 105 62.641 5.245 12.183 1.00176.51 C +ATOM 19877 CG2 VAL K 105 60.157 4.970 12.283 1.00168.26 C +ATOM 19878 N ALA K 106 63.066 4.402 9.240 1.00187.14 N +ATOM 19879 CA ALA K 106 64.241 4.492 8.382 1.00174.51 C +ATOM 19880 C ALA K 106 65.509 4.684 9.209 1.00194.14 C +ATOM 19881 O ALA K 106 65.541 5.501 10.135 1.00291.16 O +ATOM 19882 CB ALA K 106 64.076 5.636 7.395 1.00148.47 C +ATOM 19883 N ILE K 107 66.541 3.909 8.886 1.00163.48 N +ATOM 19884 CA ILE K 107 67.771 3.867 9.682 1.00148.64 C +ATOM 19885 C ILE K 107 68.442 5.253 9.816 1.00127.28 C +ATOM 19886 O ILE K 107 69.094 5.551 10.820 1.00108.47 O +ATOM 19887 CB ILE K 107 68.760 2.829 9.090 1.00148.30 C +ATOM 19888 CG1 ILE K 107 69.912 2.549 10.062 1.00150.28 C +ATOM 19889 CG2 ILE K 107 69.299 3.296 7.740 1.00144.22 C +ATOM 19890 CD1 ILE K 107 69.480 2.056 11.432 1.00137.32 C +ATOM 19891 N ASN K 108 68.272 6.098 8.801 1.00142.37 N +ATOM 19892 CA ASN K 108 68.778 7.482 8.825 1.00145.64 C +ATOM 19893 C ASN K 108 67.975 8.340 9.791 1.00143.25 C +ATOM 19894 O ASN K 108 68.507 9.233 10.445 1.00138.83 O +ATOM 19895 CB ASN K 108 68.692 8.118 7.433 1.00153.56 C +ATOM 19896 CG ASN K 108 68.850 7.103 6.315 1.00180.11 C +ATOM 19897 OD1 ASN K 108 69.966 6.792 5.899 1.00196.09 O +ATOM 19898 ND2 ASN K 108 67.728 6.571 5.829 1.00169.36 N +ATOM 19899 N ASN K 109 66.685 8.042 9.877 1.00132.49 N +ATOM 19900 CA ASN K 109 65.751 8.830 10.667 1.00130.96 C +ATOM 19901 C ASN K 109 65.679 8.392 12.131 1.00126.11 C +ATOM 19902 O ASN K 109 65.189 9.135 12.985 1.00151.81 O +ATOM 19903 CB ASN K 109 64.357 8.752 10.036 1.00140.89 C +ATOM 19904 CG ASN K 109 63.874 10.100 9.544 1.00145.07 C +ATOM 19905 OD1 ASN K 109 62.912 10.651 10.071 1.00139.08 O +ATOM 19906 ND2 ASN K 109 64.568 10.658 8.557 1.00147.45 N +ATOM 19907 N ARG K 110 66.180 7.187 12.410 1.00103.90 N +ATOM 19908 CA ARG K 110 66.068 6.543 13.731 1.00 88.68 C +ATOM 19909 C ARG K 110 66.657 7.414 14.833 1.00100.70 C +ATOM 19910 O ARG K 110 67.764 7.970 14.678 1.00107.61 O +ATOM 19911 CB ARG K 110 66.823 5.202 13.704 1.00 95.75 C +ATOM 19912 CG ARG K 110 66.371 4.191 14.743 1.00104.81 C +ATOM 19913 CD ARG K 110 66.469 2.763 14.228 1.00110.36 C +ATOM 19914 NE ARG K 110 67.791 2.169 14.478 1.00114.80 N +ATOM 19915 CZ ARG K 110 68.016 1.063 15.205 1.00126.72 C +ATOM 19916 NH1 ARG K 110 67.010 0.392 15.772 1.00119.03 N +ATOM 19917 NH2 ARG K 110 69.257 0.606 15.354 1.00118.13 N +ATOM 19918 N ILE K 111 65.935 7.551 15.947 1.00105.80 N +ATOM 19919 CA ILE K 111 66.479 8.266 17.122 1.00115.66 C +ATOM 19920 C ILE K 111 66.802 7.297 18.253 1.00118.92 C +ATOM 19921 O ILE K 111 65.901 6.667 18.760 1.00102.88 O +ATOM 19922 CB ILE K 111 65.503 9.324 17.661 1.00 93.11 C +ATOM 19923 CG1 ILE K 111 65.293 10.407 16.597 1.00 97.95 C +ATOM 19924 CG2 ILE K 111 66.057 9.948 18.934 1.00 90.44 C +ATOM 19925 CD1 ILE K 111 64.150 11.348 16.880 1.00 95.51 C +ATOM 19926 N PRO K 112 68.091 7.187 18.655 1.00109.96 N +ATOM 19927 CA PRO K 112 68.484 6.214 19.672 1.00 88.93 C +ATOM 19928 C PRO K 112 68.212 6.772 21.058 1.00106.00 C +ATOM 19929 O PRO K 112 68.564 7.944 21.329 1.00105.11 O +ATOM 19930 CB PRO K 112 69.977 6.057 19.444 1.00 88.47 C +ATOM 19931 CG PRO K 112 70.413 7.392 18.918 1.00109.51 C +ATOM 19932 CD PRO K 112 69.236 8.002 18.199 1.00117.23 C +ATOM 19933 N LEU K 113 67.512 5.984 21.885 1.00116.37 N +ATOM 19934 CA LEU K 113 66.992 6.462 23.178 1.00101.93 C +ATOM 19935 C LEU K 113 67.678 5.837 24.349 1.00 91.34 C +ATOM 19936 O LEU K 113 68.051 4.650 24.348 1.00 65.58 O +ATOM 19937 CB LEU K 113 65.512 6.198 23.340 1.00105.22 C +ATOM 19938 CG LEU K 113 64.584 7.272 22.777 1.00119.93 C +ATOM 19939 CD1 LEU K 113 63.174 6.864 23.125 1.00116.88 C +ATOM 19940 CD2 LEU K 113 64.877 8.672 23.298 1.00105.37 C +ATOM 19941 N GLN K 114 67.959 6.711 25.301 1.00100.60 N +ATOM 19942 CA GLN K 114 68.921 6.442 26.345 1.00115.12 C +ATOM 19943 C GLN K 114 68.300 7.062 27.545 1.00 93.67 C +ATOM 19944 O GLN K 114 67.573 8.053 27.420 1.00 92.11 O +ATOM 19945 CB GLN K 114 70.282 7.098 26.049 1.00127.32 C +ATOM 19946 CG GLN K 114 71.494 6.336 26.593 1.00120.64 C +ATOM 19947 CD GLN K 114 72.720 7.247 26.748 1.00150.35 C +ATOM 19948 OE1 GLN K 114 72.807 8.279 26.083 1.00144.05 O +ATOM 19949 NE2 GLN K 114 73.590 6.937 27.710 1.00143.63 N +ATOM 19950 N SER K 115 68.520 6.430 28.690 1.00 88.73 N +ATOM 19951 CA SER K 115 67.861 6.831 29.919 1.00106.78 C +ATOM 19952 C SER K 115 68.173 8.293 30.209 1.00 97.91 C +ATOM 19953 O SER K 115 69.200 8.822 29.718 1.00 94.90 O +ATOM 19954 CB SER K 115 68.322 5.954 31.083 1.00120.36 C +ATOM 19955 OG SER K 115 69.752 5.916 31.168 1.00120.57 O +ATOM 19956 N LEU K 116 67.290 8.961 30.963 1.00 72.89 N +ATOM 19957 CA LEU K 116 67.414 10.405 31.065 1.00 77.85 C +ATOM 19958 C LEU K 116 68.605 10.690 31.968 1.00 95.89 C +ATOM 19959 O LEU K 116 68.707 10.095 33.031 1.00 70.52 O +ATOM 19960 CB LEU K 116 66.181 11.051 31.636 1.00 63.38 C +ATOM 19961 CG LEU K 116 64.936 10.998 30.784 1.00 62.80 C +ATOM 19962 CD1 LEU K 116 64.077 9.763 31.179 1.00 77.09 C +ATOM 19963 CD2 LEU K 116 64.155 12.288 30.947 1.00 44.75 C +ATOM 19964 N THR K 117 69.563 11.481 31.465 1.00114.69 N +ATOM 19965 CA THR K 117 70.796 11.804 32.195 1.00 93.43 C +ATOM 19966 C THR K 117 70.405 12.417 33.498 1.00 98.04 C +ATOM 19967 O THR K 117 69.491 13.247 33.530 1.00113.14 O +ATOM 19968 CB THR K 117 71.654 12.834 31.463 1.00 81.40 C +ATOM 19969 OG1 THR K 117 71.932 12.372 30.141 1.00 98.90 O +ATOM 19970 CG2 THR K 117 72.959 13.048 32.199 1.00 92.79 C +ATOM 19971 N ALA K 118 71.026 11.946 34.573 1.00100.86 N +ATOM 19972 CA ALA K 118 70.552 12.256 35.912 1.00112.78 C +ATOM 19973 C ALA K 118 71.573 13.092 36.658 1.00 96.01 C +ATOM 19974 O ALA K 118 72.757 12.787 36.652 1.00 60.58 O +ATOM 19975 CB ALA K 118 70.236 10.985 36.698 1.00116.90 C +ATOM 19976 N ALA K 119 71.050 14.051 37.421 1.00 82.48 N +ATOM 19977 CA ALA K 119 71.860 15.025 38.147 1.00 66.08 C +ATOM 19978 C ALA K 119 72.294 14.528 39.494 1.00 67.41 C +ATOM 19979 O ALA K 119 71.595 13.686 40.116 1.00 85.71 O +ATOM 19980 CB ALA K 119 71.065 16.307 38.310 1.00 73.27 C +ATOM 19981 N ASN K 120 73.389 15.085 40.007 1.00 92.12 N +ATOM 19982 CA ASN K 120 73.797 14.766 41.387 1.00124.44 C +ATOM 19983 C ASN K 120 73.409 15.826 42.416 1.00 85.42 C +ATOM 19984 O ASN K 120 72.918 15.518 43.499 1.00 81.14 O +ATOM 19985 CB ASN K 120 75.293 14.519 41.509 1.00128.43 C +ATOM 19986 CG ASN K 120 75.683 14.076 42.921 1.00139.98 C +ATOM 19987 OD1 ASN K 120 76.704 14.532 43.443 1.00170.20 O +ATOM 19988 ND2 ASN K 120 74.846 13.222 43.569 1.00101.24 N +ATOM 19989 N ILE K 121 73.648 17.068 42.074 1.00 56.39 N +ATOM 19990 CA ILE K 121 73.186 18.134 42.908 1.00 49.06 C +ATOM 19991 C ILE K 121 72.098 18.805 42.147 1.00 43.20 C +ATOM 19992 O ILE K 121 72.163 18.964 40.916 1.00 68.59 O +ATOM 19993 CB ILE K 121 74.329 19.134 43.291 1.00 63.81 C +ATOM 19994 CG1 ILE K 121 74.790 20.011 42.109 1.00 55.00 C +ATOM 19995 CG2 ILE K 121 75.513 18.380 43.885 1.00 76.56 C +ATOM 19996 CD1 ILE K 121 74.405 21.455 42.256 1.00 50.88 C +ATOM 19997 N MET K 122 71.112 19.275 42.857 1.00 38.20 N +ATOM 19998 CA MET K 122 70.151 20.157 42.224 1.00 53.43 C +ATOM 19999 C MET K 122 70.070 21.440 43.039 1.00 49.74 C +ATOM 20000 O MET K 122 70.268 21.444 44.253 1.00 57.69 O +ATOM 20001 CB MET K 122 68.770 19.483 42.059 1.00 65.09 C +ATOM 20002 CG MET K 122 68.151 18.968 43.347 1.00 88.19 C +ATOM 20003 SD MET K 122 66.371 18.903 43.206 1.00 68.42 S +ATOM 20004 CE MET K 122 65.888 19.577 44.830 1.00104.17 C +ATOM 20005 N VAL K 123 69.866 22.548 42.353 1.00 49.90 N +ATOM 20006 CA VAL K 123 69.901 23.845 43.000 1.00 58.68 C +ATOM 20007 C VAL K 123 68.566 24.462 42.794 1.00 54.10 C +ATOM 20008 O VAL K 123 68.138 24.662 41.664 1.00 52.98 O +ATOM 20009 CB VAL K 123 71.034 24.803 42.467 1.00 63.91 C +ATOM 20010 CG1 VAL K 123 71.201 24.678 40.965 1.00 74.33 C +ATOM 20011 CG2 VAL K 123 70.773 26.256 42.873 1.00 59.13 C +ATOM 20012 N GLU K 124 67.949 24.870 43.892 1.00 68.13 N +ATOM 20013 CA GLU K 124 66.741 25.700 43.806 1.00 83.81 C +ATOM 20014 C GLU K 124 66.892 26.978 44.600 1.00 57.57 C +ATOM 20015 O GLU K 124 67.799 27.114 45.409 1.00 61.25 O +ATOM 20016 CB GLU K 124 65.508 24.903 44.260 1.00 95.43 C +ATOM 20017 CG GLU K 124 65.782 23.830 45.296 1.00 91.85 C +ATOM 20018 CD GLU K 124 64.635 22.855 45.372 1.00 85.65 C +ATOM 20019 OE1 GLU K 124 64.065 22.503 44.313 1.00111.47 O +ATOM 20020 OE2 GLU K 124 64.360 22.361 46.473 1.00 95.81 O +ATOM 20021 N GLY K 125 65.920 27.848 44.452 1.00 48.19 N +ATOM 20022 CA GLY K 125 65.945 29.095 45.157 1.00 51.56 C +ATOM 20023 C GLY K 125 64.649 29.846 45.028 1.00 60.27 C +ATOM 20024 O GLY K 125 63.607 29.292 44.629 1.00 83.90 O +ATOM 20025 N SER K 126 64.721 31.149 45.237 1.00 62.34 N +ATOM 20026 CA SER K 126 63.518 31.953 45.188 1.00 74.30 C +ATOM 20027 C SER K 126 63.929 33.394 44.966 1.00 66.86 C +ATOM 20028 O SER K 126 64.919 33.832 45.522 1.00 43.83 O +ATOM 20029 CB SER K 126 62.714 31.790 46.505 1.00 85.69 C +ATOM 20030 OG SER K 126 62.867 30.492 47.097 1.00 62.84 O +ATOM 20031 N ILE K 127 63.067 34.157 44.313 1.00 76.01 N +ATOM 20032 CA ILE K 127 63.130 35.591 44.465 1.00 92.61 C +ATOM 20033 C ILE K 127 62.523 35.979 45.831 1.00100.98 C +ATOM 20034 O ILE K 127 61.316 36.070 45.986 1.00130.65 O +ATOM 20035 CB ILE K 127 62.419 36.333 43.317 1.00 90.38 C +ATOM 20036 CG1 ILE K 127 63.121 36.007 41.995 1.00 92.54 C +ATOM 20037 CG2 ILE K 127 62.413 37.848 43.570 1.00 79.64 C +ATOM 20038 CD1 ILE K 127 62.194 36.015 40.792 1.00 90.11 C +ATOM 20039 N ILE K 128 63.398 36.247 46.803 1.00 81.26 N +ATOM 20040 CA ILE K 128 63.017 36.710 48.163 1.00 52.00 C +ATOM 20041 C ILE K 128 62.990 38.236 48.164 1.00 64.19 C +ATOM 20042 O ILE K 128 64.042 38.917 48.037 1.00116.28 O +ATOM 20043 CB ILE K 128 63.985 36.166 49.193 1.00 37.41 C +ATOM 20044 CG1 ILE K 128 65.438 36.509 48.824 1.00 44.49 C +ATOM 20045 CG2 ILE K 128 63.951 34.657 49.167 1.00 36.45 C +ATOM 20046 CD1 ILE K 128 66.391 36.505 50.014 1.00 42.96 C +ATOM 20047 N GLY K 129 61.799 38.768 47.935 1.00 65.61 N +ATOM 20048 CA GLY K 129 61.596 40.180 48.107 1.00 73.39 C +ATOM 20049 C GLY K 129 61.813 41.051 46.874 1.00 74.27 C +ATOM 20050 O GLY K 129 62.895 41.034 46.231 1.00 73.13 O +ATOM 20051 N TYR K 130 60.909 42.019 46.753 1.00 76.08 N +ATOM 20052 CA TYR K 130 61.180 43.249 46.034 1.00 94.59 C +ATOM 20053 C TYR K 130 60.555 44.353 46.846 1.00101.17 C +ATOM 20054 O TYR K 130 59.343 44.438 46.942 1.00 96.01 O +ATOM 20055 CB TYR K 130 60.554 43.150 44.651 1.00113.42 C +ATOM 20056 CG TYR K 130 60.619 44.402 43.779 1.00126.85 C +ATOM 20057 CD1 TYR K 130 59.760 45.475 43.999 1.00127.64 C +ATOM 20058 CD2 TYR K 130 61.440 44.441 42.648 1.00114.61 C +ATOM 20059 CE1 TYR K 130 59.802 46.604 43.197 1.00104.28 C +ATOM 20060 CE2 TYR K 130 61.471 45.554 41.830 1.00 99.84 C +ATOM 20061 CZ TYR K 130 60.674 46.639 42.128 1.00 89.81 C +ATOM 20062 OH TYR K 130 60.717 47.714 41.303 1.00 78.87 O +ATOM 20063 N GLU K 131 61.378 45.195 47.467 1.00114.22 N +ATOM 20064 CA GLU K 131 60.869 46.421 48.090 1.00122.44 C +ATOM 20065 C GLU K 131 61.045 47.604 47.144 1.00 94.31 C +ATOM 20066 O GLU K 131 61.967 47.607 46.319 1.00 85.54 O +ATOM 20067 CB GLU K 131 61.601 46.668 49.395 1.00157.39 C +ATOM 20068 CG GLU K 131 61.019 47.766 50.274 1.00155.53 C +ATOM 20069 CD GLU K 131 59.925 47.286 51.215 1.00138.81 C +ATOM 20070 OE1 GLU K 131 59.935 46.084 51.600 1.00140.03 O +ATOM 20071 OE2 GLU K 131 59.074 48.122 51.586 1.00127.73 O +ATOM 20072 N SER K 132 60.104 48.545 47.177 1.00 80.69 N +ATOM 20073 CA SER K 132 60.059 49.599 46.160 1.00 91.45 C +ATOM 20074 C SER K 132 60.233 50.992 46.760 1.00 96.41 C +ATOM 20075 O SER K 132 59.690 51.276 47.838 1.00131.03 O +ATOM 20076 CB SER K 132 58.750 49.521 45.375 1.00 93.96 C +ATOM 20077 OG SER K 132 57.925 50.642 45.639 1.00103.09 O +ATOM 20078 N ASN K 133 60.963 51.853 46.050 1.00 83.85 N +ATOM 20079 CA ASN K 133 61.385 53.144 46.595 1.00102.13 C +ATOM 20080 C ASN K 133 61.969 52.986 47.989 1.00107.24 C +ATOM 20081 O ASN K 133 61.523 53.622 48.953 1.00102.02 O +ATOM 20082 CB ASN K 133 60.233 54.147 46.639 1.00107.30 C +ATOM 20083 CG ASN K 133 59.660 54.432 45.264 1.00126.01 C +ATOM 20084 OD1 ASN K 133 60.351 54.341 44.242 1.00109.94 O +ATOM 20085 ND2 ASN K 133 58.373 54.743 45.233 1.00134.60 N +ATOM 20086 N VAL K 134 62.990 52.139 48.075 1.00102.17 N +ATOM 20087 CA VAL K 134 63.703 51.896 49.323 1.00101.20 C +ATOM 20088 C VAL K 134 64.462 53.177 49.695 1.00117.95 C +ATOM 20089 O VAL K 134 64.539 53.549 50.868 1.00115.14 O +ATOM 20090 CB VAL K 134 64.681 50.714 49.177 1.00100.16 C +ATOM 20091 CG1 VAL K 134 65.362 50.401 50.490 1.00111.89 C +ATOM 20092 CG2 VAL K 134 63.949 49.481 48.666 1.00111.02 C +ATOM 20093 N LYS K 135 64.948 53.889 48.678 1.00132.38 N +ATOM 20094 CA LYS K 135 65.342 55.290 48.847 1.00115.74 C +ATOM 20095 C LYS K 135 64.820 56.152 47.712 1.00117.65 C +ATOM 20096 O LYS K 135 64.521 55.662 46.597 1.00144.00 O +ATOM 20097 CB LYS K 135 66.854 55.401 48.909 1.00110.33 C +ATOM 20098 CG LYS K 135 67.453 54.673 50.095 1.00118.58 C +ATOM 20099 CD LYS K 135 68.969 54.722 50.030 1.00123.65 C +ATOM 20100 CE LYS K 135 69.610 54.002 51.197 1.00123.36 C +ATOM 20101 NZ LYS K 135 71.009 54.469 51.393 1.00100.30 N +ATOM 20102 N SER K 136 64.751 57.450 47.979 1.00104.88 N +ATOM 20103 CA SER K 136 64.332 58.406 46.963 1.00115.17 C +ATOM 20104 C SER K 136 64.740 59.823 47.323 1.00128.65 C +ATOM 20105 O SER K 136 64.957 60.131 48.493 1.00172.97 O +ATOM 20106 CB SER K 136 62.823 58.321 46.748 1.00 99.46 C +ATOM 20107 OG SER K 136 62.201 59.582 46.920 1.00 99.27 O +ATOM 20108 N GLY K 137 64.856 60.679 46.312 1.00120.82 N +ATOM 20109 CA GLY K 137 65.180 62.077 46.547 1.00137.43 C +ATOM 20110 C GLY K 137 64.954 62.966 45.345 1.00143.66 C +ATOM 20111 O GLY K 137 64.596 62.498 44.267 1.00159.67 O +ATOM 20112 N GLY K 138 65.130 64.271 45.541 1.00173.66 N +ATOM 20113 CA GLY K 138 64.984 65.237 44.452 1.00175.73 C +ATOM 20114 C GLY K 138 65.581 66.597 44.757 1.00163.36 C +ATOM 20115 O GLY K 138 65.577 67.037 45.908 1.00177.15 O +ATOM 20116 N VAL K 139 66.134 67.236 43.728 1.00136.61 N +ATOM 20117 CA VAL K 139 66.727 68.563 43.868 1.00133.07 C +ATOM 20118 C VAL K 139 66.388 69.413 42.660 1.00134.05 C +ATOM 20119 O VAL K 139 66.638 69.012 41.521 1.00155.04 O +ATOM 20120 CB VAL K 139 68.262 68.506 43.993 1.00125.15 C +ATOM 20121 CG1 VAL K 139 68.840 69.911 44.005 1.00109.32 C +ATOM 20122 CG2 VAL K 139 68.679 67.756 45.253 1.00154.83 C +ATOM 20123 N GLY K 140 65.834 70.598 42.907 1.00143.61 N +ATOM 20124 CA GLY K 140 65.435 71.509 41.829 1.00157.51 C +ATOM 20125 C GLY K 140 65.531 72.988 42.168 1.00148.53 C +ATOM 20126 O GLY K 140 65.284 73.389 43.300 1.00157.31 O +ATOM 20127 N ALA K 141 65.876 73.798 41.172 1.00143.34 N +ATOM 20128 CA ALA K 141 65.998 75.237 41.355 1.00132.79 C +ATOM 20129 C ALA K 141 65.560 76.021 40.109 1.00147.16 C +ATOM 20130 O ALA K 141 65.805 75.611 38.970 1.00173.00 O +ATOM 20131 CB ALA K 141 67.427 75.586 41.730 1.00115.21 C +ATOM 20132 N ARG K 142 64.867 77.127 40.338 1.00163.28 N +ATOM 20133 CA ARG K 142 64.505 78.022 39.259 1.00170.18 C +ATOM 20134 C ARG K 142 64.918 79.437 39.630 1.00190.39 C +ATOM 20135 O ARG K 142 64.884 79.819 40.800 1.00189.13 O +ATOM 20136 CB ARG K 142 63.005 77.951 38.961 1.00182.22 C +ATOM 20137 CG ARG K 142 62.585 78.806 37.769 1.00193.19 C +ATOM 20138 CD ARG K 142 61.582 78.110 36.862 1.00189.16 C +ATOM 20139 NE ARG K 142 60.200 78.296 37.293 1.00187.90 N +ATOM 20140 CZ ARG K 142 59.190 77.490 36.981 1.00176.62 C +ATOM 20141 NH1 ARG K 142 59.404 76.385 36.280 1.00188.13 N +ATOM 20142 NH2 ARG K 142 57.962 77.769 37.405 1.00163.35 N +ATOM 20143 N TYR K 143 65.352 80.195 38.626 1.00206.13 N +ATOM 20144 CA TYR K 143 65.949 81.515 38.842 1.00195.59 C +ATOM 20145 C TYR K 143 65.333 82.570 37.918 1.00166.86 C +ATOM 20146 O TYR K 143 65.851 82.858 36.835 1.00105.04 O +ATOM 20147 CB TYR K 143 67.455 81.427 38.619 1.00209.05 C +ATOM 20148 CG TYR K 143 68.235 82.649 38.976 1.00206.29 C +ATOM 20149 CD1 TYR K 143 68.490 82.963 40.309 1.00187.09 C +ATOM 20150 CD2 TYR K 143 68.850 83.405 37.986 1.00190.16 C +ATOM 20151 CE1 TYR K 143 69.287 84.038 40.647 1.00169.19 C +ATOM 20152 CE2 TYR K 143 69.659 84.479 38.316 1.00171.40 C +ATOM 20153 CZ TYR K 143 69.868 84.793 39.645 1.00163.93 C +ATOM 20154 OH TYR K 143 70.654 85.870 39.976 1.00169.76 O +ATOM 20155 N GLY K 145 63.741 82.880 35.709 1.00105.70 N +ATOM 20156 CA GLY K 145 63.181 82.386 34.455 1.00124.62 C +ATOM 20157 C GLY K 145 63.637 80.989 34.034 1.00136.55 C +ATOM 20158 O GLY K 145 62.942 80.328 33.260 1.00130.18 O +ATOM 20159 N ILE K 146 64.813 80.560 34.490 1.00152.03 N +ATOM 20160 CA ILE K 146 65.441 79.319 34.007 1.00154.09 C +ATOM 20161 C ILE K 146 65.472 78.319 35.161 1.00179.62 C +ATOM 20162 O ILE K 146 65.766 78.689 36.294 1.00220.04 O +ATOM 20163 CB ILE K 146 66.885 79.561 33.476 1.00140.70 C +ATOM 20164 CG1 ILE K 146 66.963 80.879 32.681 1.00124.51 C +ATOM 20165 CG2 ILE K 146 67.348 78.393 32.612 1.00104.72 C +ATOM 20166 CD1 ILE K 146 67.459 82.059 33.489 1.00107.00 C +ATOM 20167 N GLY K 147 65.152 77.059 34.894 1.00174.06 N +ATOM 20168 CA GLY K 147 65.071 76.076 35.976 1.00174.04 C +ATOM 20169 C GLY K 147 65.412 74.656 35.591 1.00162.39 C +ATOM 20170 O GLY K 147 65.283 74.261 34.443 1.00177.71 O +ATOM 20171 N ALA K 148 65.837 73.877 36.577 1.00160.41 N +ATOM 20172 CA ALA K 148 66.066 72.456 36.381 1.00132.08 C +ATOM 20173 C ALA K 148 65.753 71.690 37.664 1.00133.45 C +ATOM 20174 O ALA K 148 65.577 72.276 38.739 1.00166.74 O +ATOM 20175 CB ALA K 148 67.495 72.199 35.914 1.00 95.94 C +ATOM 20176 N ASP K 149 65.635 70.378 37.532 1.00145.98 N +ATOM 20177 CA ASP K 149 65.429 69.511 38.684 1.00154.50 C +ATOM 20178 C ASP K 149 65.732 68.057 38.327 1.00158.15 C +ATOM 20179 O ASP K 149 65.553 67.645 37.178 1.00131.35 O +ATOM 20180 CB ASP K 149 64.002 69.655 39.223 1.00127.93 C +ATOM 20181 CG ASP K 149 63.017 68.860 38.445 1.00129.89 C +ATOM 20182 OD1 ASP K 149 62.670 69.295 37.325 1.00166.96 O +ATOM 20183 OD2 ASP K 149 62.587 67.799 38.941 1.00114.14 O +ATOM 20184 N THR K 150 66.262 67.307 39.289 1.00156.08 N +ATOM 20185 CA THR K 150 66.322 65.862 39.146 1.00144.41 C +ATOM 20186 C THR K 150 65.570 65.209 40.287 1.00141.52 C +ATOM 20187 O THR K 150 65.383 65.803 41.354 1.00123.83 O +ATOM 20188 CB THR K 150 67.765 65.318 39.111 1.00121.44 C +ATOM 20189 OG1 THR K 150 68.430 65.684 40.319 1.00155.88 O +ATOM 20190 CG2 THR K 150 68.518 65.860 37.915 1.00102.62 C +ATOM 20191 N GLN K 151 65.082 64.003 40.020 1.00142.18 N +ATOM 20192 CA GLN K 151 64.444 63.171 41.024 1.00133.99 C +ATOM 20193 C GLN K 151 64.911 61.740 40.847 1.00131.89 C +ATOM 20194 O GLN K 151 65.157 61.316 39.728 1.00187.56 O +ATOM 20195 CB GLN K 151 62.936 63.236 40.857 1.00104.20 C +ATOM 20196 CG GLN K 151 62.359 64.562 41.283 1.00110.85 C +ATOM 20197 CD GLN K 151 61.023 64.823 40.641 1.00139.17 C +ATOM 20198 OE1 GLN K 151 60.206 63.916 40.531 1.00138.89 O +ATOM 20199 NE2 GLN K 151 60.790 66.066 40.210 1.00156.44 N +ATOM 20200 N TYR K 152 65.125 61.025 41.943 1.00109.81 N +ATOM 20201 CA TYR K 152 65.592 59.655 41.826 1.00 96.54 C +ATOM 20202 C TYR K 152 64.871 58.766 42.791 1.00107.55 C +ATOM 20203 O TYR K 152 64.519 59.191 43.902 1.00119.78 O +ATOM 20204 CB TYR K 152 67.107 59.569 42.010 1.00 89.08 C +ATOM 20205 CG TYR K 152 67.588 59.037 43.340 1.00 90.29 C +ATOM 20206 CD1 TYR K 152 67.387 59.755 44.550 1.00 84.66 C +ATOM 20207 CD2 TYR K 152 68.368 57.897 43.382 1.00 80.30 C +ATOM 20208 CE1 TYR K 152 67.893 59.293 45.766 1.00 68.99 C +ATOM 20209 CE2 TYR K 152 68.926 57.455 44.588 1.00 87.28 C +ATOM 20210 CZ TYR K 152 68.697 58.157 45.774 1.00 76.22 C +ATOM 20211 OH TYR K 152 69.234 57.673 46.938 1.00 56.57 O +ATOM 20212 N GLN K 153 64.641 57.529 42.369 1.00104.48 N +ATOM 20213 CA GLN K 153 64.159 56.502 43.284 1.00113.28 C +ATOM 20214 C GLN K 153 64.924 55.200 43.083 1.00113.48 C +ATOM 20215 O GLN K 153 65.517 54.980 42.011 1.00166.50 O +ATOM 20216 CB GLN K 153 62.679 56.265 43.053 1.00112.64 C +ATOM 20217 CG GLN K 153 61.775 57.455 43.390 1.00129.00 C +ATOM 20218 CD GLN K 153 60.311 57.179 43.004 1.00145.60 C +ATOM 20219 OE1 GLN K 153 60.026 56.296 42.187 1.00148.24 O +ATOM 20220 NE2 GLN K 153 59.386 57.932 43.591 1.00157.96 N +ATOM 20221 N LEU K 154 65.011 54.387 44.137 1.00 83.59 N +ATOM 20222 CA LEU K 154 65.638 53.081 43.986 1.00 80.16 C +ATOM 20223 C LEU K 154 64.956 52.009 44.799 1.00 89.17 C +ATOM 20224 O LEU K 154 64.520 52.245 45.938 1.00 97.42 O +ATOM 20225 CB LEU K 154 67.132 53.127 44.307 1.00 75.08 C +ATOM 20226 CG LEU K 154 67.489 53.321 45.777 1.00 92.26 C +ATOM 20227 CD1 LEU K 154 67.759 51.986 46.449 1.00 97.98 C +ATOM 20228 CD2 LEU K 154 68.698 54.235 45.898 1.00116.09 C +ATOM 20229 N ASP K 155 64.975 50.804 44.222 1.00105.74 N +ATOM 20230 CA ASP K 155 64.217 49.636 44.690 1.00 94.03 C +ATOM 20231 C ASP K 155 65.199 48.496 44.974 1.00 95.40 C +ATOM 20232 O ASP K 155 66.346 48.527 44.520 1.00 84.48 O +ATOM 20233 CB ASP K 155 63.225 49.177 43.619 1.00 89.29 C +ATOM 20234 CG ASP K 155 62.436 50.334 43.025 1.00130.82 C +ATOM 20235 OD1 ASP K 155 62.991 51.065 42.166 1.00196.65 O +ATOM 20236 OD2 ASP K 155 61.287 50.554 43.449 1.00123.77 O +ATOM 20237 N GLN K 156 64.765 47.511 45.754 1.00101.96 N +ATOM 20238 CA GLN K 156 65.639 46.393 46.107 1.00 90.90 C +ATOM 20239 C GLN K 156 65.089 45.078 45.552 1.00 68.14 C +ATOM 20240 O GLN K 156 63.887 44.945 45.324 1.00 53.96 O +ATOM 20241 CB GLN K 156 65.812 46.313 47.628 1.00 99.99 C +ATOM 20242 CG GLN K 156 66.913 45.370 48.064 1.00110.17 C +ATOM 20243 CD GLN K 156 67.450 45.700 49.439 1.00 99.61 C +ATOM 20244 OE1 GLN K 156 66.865 46.498 50.181 1.00 71.71 O +ATOM 20245 NE2 GLN K 156 68.528 45.015 49.826 1.00 99.29 N +ATOM 20246 N ILE K 157 65.980 44.127 45.317 1.00 49.94 N +ATOM 20247 CA ILE K 157 65.585 42.801 44.922 1.00 63.64 C +ATOM 20248 C ILE K 157 66.599 41.798 45.482 1.00 65.01 C +ATOM 20249 O ILE K 157 67.792 42.060 45.519 1.00 46.15 O +ATOM 20250 CB ILE K 157 65.509 42.709 43.381 1.00 92.42 C +ATOM 20251 CG1 ILE K 157 64.553 41.579 42.947 1.00118.61 C +ATOM 20252 CG2 ILE K 157 66.890 42.503 42.776 1.00 78.53 C +ATOM 20253 CD1 ILE K 157 64.265 41.554 41.454 1.00118.22 C +ATOM 20254 N ALA K 158 66.116 40.661 45.979 1.00 76.83 N +ATOM 20255 CA ALA K 158 67.023 39.684 46.606 1.00 61.19 C +ATOM 20256 C ALA K 158 66.695 38.292 46.127 1.00 46.91 C +ATOM 20257 O ALA K 158 65.544 38.022 45.711 1.00 60.79 O +ATOM 20258 CB ALA K 158 66.945 39.760 48.118 1.00 52.64 C +ATOM 20259 N VAL K 159 67.705 37.442 46.120 1.00 31.80 N +ATOM 20260 CA VAL K 159 67.581 36.158 45.515 1.00 37.25 C +ATOM 20261 C VAL K 159 68.286 35.140 46.347 1.00 50.46 C +ATOM 20262 O VAL K 159 69.440 35.319 46.726 1.00 65.35 O +ATOM 20263 CB VAL K 159 68.150 36.120 44.082 1.00 41.32 C +ATOM 20264 CG1 VAL K 159 68.474 34.703 43.647 1.00 43.06 C +ATOM 20265 CG2 VAL K 159 67.142 36.713 43.097 1.00 57.66 C +ATOM 20266 N ASN K 160 67.562 34.068 46.676 1.00 73.27 N +ATOM 20267 CA ASN K 160 68.146 32.905 47.341 1.00 73.45 C +ATOM 20268 C ASN K 160 68.437 31.861 46.274 1.00 58.33 C +ATOM 20269 O ASN K 160 67.583 31.567 45.429 1.00 38.30 O +ATOM 20270 CB ASN K 160 67.166 32.353 48.381 1.00 86.94 C +ATOM 20271 CG ASN K 160 67.661 31.080 49.060 1.00112.65 C +ATOM 20272 OD1 ASN K 160 68.106 30.132 48.409 1.00145.68 O +ATOM 20273 ND2 ASN K 160 67.507 31.023 50.368 1.00122.31 N +ATOM 20274 N LEU K 161 69.669 31.360 46.280 1.00 48.60 N +ATOM 20275 CA LEU K 161 69.979 30.119 45.597 1.00 51.85 C +ATOM 20276 C LEU K 161 70.595 29.119 46.571 1.00 43.15 C +ATOM 20277 O LEU K 161 71.272 29.493 47.488 1.00 40.02 O +ATOM 20278 CB LEU K 161 70.948 30.369 44.447 1.00 56.95 C +ATOM 20279 CG LEU K 161 70.427 31.244 43.314 1.00 60.69 C +ATOM 20280 CD1 LEU K 161 71.564 31.559 42.360 1.00 71.39 C +ATOM 20281 CD2 LEU K 161 69.279 30.525 42.594 1.00 55.02 C +ATOM 20282 N ARG K 162 70.343 27.845 46.366 1.00 49.06 N +ATOM 20283 CA ARG K 162 70.861 26.860 47.278 1.00 59.33 C +ATOM 20284 C ARG K 162 71.031 25.476 46.663 1.00 61.97 C +ATOM 20285 O ARG K 162 70.150 24.945 45.979 1.00 65.97 O +ATOM 20286 CB ARG K 162 70.003 26.786 48.545 1.00 92.28 C +ATOM 20287 CG ARG K 162 68.552 26.324 48.391 1.00129.44 C +ATOM 20288 CD ARG K 162 67.982 25.909 49.751 1.00135.98 C +ATOM 20289 NE ARG K 162 66.662 25.283 49.670 1.00124.26 N +ATOM 20290 CZ ARG K 162 65.510 25.951 49.555 1.00123.03 C +ATOM 20291 NH1 ARG K 162 65.488 27.279 49.456 1.00 82.91 N +ATOM 20292 NH2 ARG K 162 64.368 25.270 49.501 1.00149.24 N +ATOM 20293 N VAL K 163 72.217 24.927 46.879 1.00 75.96 N +ATOM 20294 CA VAL K 163 72.585 23.593 46.389 1.00 84.17 C +ATOM 20295 C VAL K 163 72.123 22.527 47.358 1.00 72.33 C +ATOM 20296 O VAL K 163 72.530 22.528 48.523 1.00 98.40 O +ATOM 20297 CB VAL K 163 74.113 23.417 46.270 1.00 98.66 C +ATOM 20298 CG1 VAL K 163 74.452 21.995 45.788 1.00 75.48 C +ATOM 20299 CG2 VAL K 163 74.715 24.508 45.380 1.00109.22 C +ATOM 20300 N VAL K 164 71.326 21.602 46.844 1.00 56.67 N +ATOM 20301 CA VAL K 164 70.815 20.499 47.615 1.00 38.48 C +ATOM 20302 C VAL K 164 71.400 19.245 47.118 1.00 36.99 C +ATOM 20303 O VAL K 164 71.463 19.019 45.888 1.00 49.27 O +ATOM 20304 CB VAL K 164 69.317 20.402 47.449 1.00 32.14 C +ATOM 20305 CG1 VAL K 164 68.807 19.217 48.227 1.00 31.88 C +ATOM 20306 CG2 VAL K 164 68.648 21.686 47.944 1.00 34.03 C +ATOM 20307 N ASN K 165 71.862 18.437 48.040 1.00 41.17 N +ATOM 20308 CA ASN K 165 72.376 17.133 47.664 1.00 75.90 C +ATOM 20309 C ASN K 165 71.272 16.090 47.445 1.00 80.74 C +ATOM 20310 O ASN K 165 70.548 15.755 48.379 1.00126.54 O +ATOM 20311 CB ASN K 165 73.334 16.600 48.722 1.00 96.60 C +ATOM 20312 CG ASN K 165 73.955 15.291 48.306 1.00102.45 C +ATOM 20313 OD1 ASN K 165 74.065 15.007 47.082 1.00149.21 O +ATOM 20314 ND2 ASN K 165 74.599 14.638 49.259 1.00106.23 N +ATOM 20315 N VAL K 166 71.181 15.554 46.226 1.00 84.80 N +ATOM 20316 CA VAL K 166 70.128 14.612 45.847 1.00 63.87 C +ATOM 20317 C VAL K 166 70.260 13.378 46.689 1.00 68.03 C +ATOM 20318 O VAL K 166 69.238 12.834 47.126 1.00107.06 O +ATOM 20319 CB VAL K 166 70.241 14.220 44.362 1.00 74.92 C +ATOM 20320 CG1 VAL K 166 69.646 12.844 44.088 1.00 89.26 C +ATOM 20321 CG2 VAL K 166 69.629 15.300 43.472 1.00 57.23 C +ATOM 20322 N SER K 167 71.503 12.961 46.970 1.00 60.22 N +ATOM 20323 CA SER K 167 71.740 11.698 47.640 1.00 59.22 C +ATOM 20324 C SER K 167 71.374 11.716 49.141 1.00 72.33 C +ATOM 20325 O SER K 167 71.192 10.644 49.757 1.00 61.46 O +ATOM 20326 CB SER K 167 73.187 11.316 47.492 1.00 60.05 C +ATOM 20327 OG SER K 167 73.608 11.495 46.167 1.00 56.80 O +ATOM 20328 N THR K 168 71.195 12.912 49.720 1.00 73.22 N +ATOM 20329 CA THR K 168 70.787 13.022 51.145 1.00 63.42 C +ATOM 20330 C THR K 168 69.634 14.013 51.481 1.00 65.40 C +ATOM 20331 O THR K 168 68.845 13.826 52.421 1.00 52.37 O +ATOM 20332 CB THR K 168 71.996 13.461 51.955 1.00 63.96 C +ATOM 20333 OG1 THR K 168 72.543 14.615 51.346 1.00 32.93 O +ATOM 20334 CG2 THR K 168 73.008 12.326 52.003 1.00 82.58 C +ATOM 20335 N GLY K 169 69.531 15.080 50.706 1.00 64.87 N +ATOM 20336 CA GLY K 169 68.590 16.131 51.020 1.00 49.47 C +ATOM 20337 C GLY K 169 69.288 17.218 51.811 1.00 51.23 C +ATOM 20338 O GLY K 169 68.694 18.266 52.046 1.00 59.35 O +ATOM 20339 N GLU K 170 70.519 16.954 52.294 1.00 43.34 N +ATOM 20340 CA GLU K 170 71.326 17.996 52.943 1.00 39.46 C +ATOM 20341 C GLU K 170 71.378 19.122 51.959 1.00 37.12 C +ATOM 20342 O GLU K 170 71.764 18.927 50.808 1.00 58.19 O +ATOM 20343 CB GLU K 170 72.727 17.491 53.280 1.00 47.25 C +ATOM 20344 CG GLU K 170 72.778 16.600 54.521 1.00 88.18 C +ATOM 20345 CD GLU K 170 73.738 15.398 54.445 1.00 98.09 C +ATOM 20346 OE1 GLU K 170 74.287 15.147 53.373 1.00 70.42 O +ATOM 20347 OE2 GLU K 170 74.005 14.761 55.501 1.00112.24 O +ATOM 20348 N ILE K 171 70.962 20.302 52.365 1.00 34.76 N +ATOM 20349 CA ILE K 171 71.430 21.485 51.675 1.00 43.22 C +ATOM 20350 C ILE K 171 72.979 21.667 51.788 1.00 60.52 C +ATOM 20351 O ILE K 171 73.517 21.695 52.894 1.00 57.65 O +ATOM 20352 CB ILE K 171 70.730 22.742 52.197 1.00 30.45 C +ATOM 20353 CG1 ILE K 171 69.270 22.629 51.832 1.00 25.32 C +ATOM 20354 CG2 ILE K 171 71.397 24.000 51.619 1.00 25.41 C +ATOM 20355 CD1 ILE K 171 68.417 23.603 52.592 1.00 25.38 C +ATOM 20356 N LEU K 172 73.692 21.733 50.649 1.00 69.31 N +ATOM 20357 CA LEU K 172 75.161 21.838 50.669 1.00 79.36 C +ATOM 20358 C LEU K 172 75.666 23.303 50.632 1.00 96.24 C +ATOM 20359 O LEU K 172 76.861 23.603 50.880 1.00 66.39 O +ATOM 20360 CB LEU K 172 75.791 21.043 49.526 1.00 84.99 C +ATOM 20361 CG LEU K 172 76.129 19.549 49.695 1.00104.19 C +ATOM 20362 CD1 LEU K 172 75.219 18.977 50.746 1.00102.93 C +ATOM 20363 CD2 LEU K 172 76.192 18.684 48.441 1.00 98.59 C +ATOM 20364 N SER K 173 74.734 24.217 50.340 1.00 84.16 N +ATOM 20365 CA SER K 173 75.056 25.636 50.265 1.00 67.41 C +ATOM 20366 C SER K 173 73.814 26.481 50.087 1.00 59.47 C +ATOM 20367 O SER K 173 72.994 26.222 49.236 1.00 65.12 O +ATOM 20368 CB SER K 173 76.004 25.915 49.090 1.00 67.09 C +ATOM 20369 OG SER K 173 76.054 27.303 48.826 1.00 86.25 O +ATOM 20370 N SER K 174 73.691 27.521 50.891 1.00 76.85 N +ATOM 20371 CA SER K 174 72.664 28.549 50.679 1.00 79.01 C +ATOM 20372 C SER K 174 73.353 29.891 50.551 1.00 92.83 C +ATOM 20373 O SER K 174 74.256 30.220 51.330 1.00106.24 O +ATOM 20374 CB SER K 174 71.646 28.598 51.852 1.00 79.42 C +ATOM 20375 OG SER K 174 70.520 29.412 51.572 1.00 40.43 O +ATOM 20376 N VAL K 175 72.893 30.682 49.591 1.00104.84 N +ATOM 20377 CA VAL K 175 73.417 32.033 49.385 1.00 86.07 C +ATOM 20378 C VAL K 175 72.307 33.049 49.134 1.00 66.32 C +ATOM 20379 O VAL K 175 71.301 32.737 48.480 1.00 48.70 O +ATOM 20380 CB VAL K 175 74.410 32.062 48.214 1.00 98.40 C +ATOM 20381 CG1 VAL K 175 75.616 31.184 48.514 1.00114.73 C +ATOM 20382 CG2 VAL K 175 73.760 31.593 46.924 1.00112.39 C +ATOM 20383 N ASN K 176 72.519 34.257 49.641 1.00 61.38 N +ATOM 20384 CA ASN K 176 71.521 35.309 49.584 1.00 76.74 C +ATOM 20385 C ASN K 176 72.041 36.596 48.932 1.00 77.73 C +ATOM 20386 O ASN K 176 72.581 37.436 49.629 1.00 91.70 O +ATOM 20387 CB ASN K 176 71.035 35.586 51.007 1.00 76.17 C +ATOM 20388 CG ASN K 176 69.717 34.857 51.309 1.00 93.51 C +ATOM 20389 OD1 ASN K 176 69.394 33.906 50.600 1.00 60.69 O +ATOM 20390 ND2 ASN K 176 69.007 35.219 52.411 1.00116.64 N +ATOM 20391 N THR K 177 71.797 36.780 47.625 1.00 62.88 N +ATOM 20392 CA THR K 177 72.281 37.960 46.900 1.00 49.38 C +ATOM 20393 C THR K 177 71.193 39.031 46.761 1.00 56.80 C +ATOM 20394 O THR K 177 70.012 38.767 46.968 1.00 49.88 O +ATOM 20395 CB THR K 177 72.777 37.605 45.505 1.00 42.37 C +ATOM 20396 OG1 THR K 177 71.668 37.254 44.677 1.00 45.60 O +ATOM 20397 CG2 THR K 177 73.749 36.437 45.543 1.00 43.97 C +ATOM 20398 N SER K 178 71.622 40.258 46.491 1.00 68.42 N +ATOM 20399 CA SER K 178 70.726 41.419 46.494 1.00 64.50 C +ATOM 20400 C SER K 178 71.215 42.433 45.502 1.00 67.79 C +ATOM 20401 O SER K 178 72.424 42.556 45.237 1.00 88.94 O +ATOM 20402 CB SER K 178 70.633 42.087 47.890 1.00 65.64 C +ATOM 20403 OG SER K 178 70.040 43.386 47.815 1.00 41.53 O +ATOM 20404 N LYS K 179 70.291 43.225 45.006 1.00 70.19 N +ATOM 20405 CA LYS K 179 70.630 44.168 43.950 1.00 89.69 C +ATOM 20406 C LYS K 179 69.624 45.323 43.877 1.00 76.89 C +ATOM 20407 O LYS K 179 68.454 45.179 44.227 1.00 63.93 O +ATOM 20408 CB LYS K 179 70.652 43.429 42.619 1.00115.29 C +ATOM 20409 CG LYS K 179 71.712 43.905 41.643 1.00101.98 C +ATOM 20410 CD LYS K 179 71.121 44.949 40.710 1.00110.94 C +ATOM 20411 CE LYS K 179 72.198 45.545 39.841 1.00121.53 C +ATOM 20412 NZ LYS K 179 71.720 46.763 39.146 1.00118.83 N +ATOM 20413 N THR K 180 70.119 46.479 43.475 1.00 55.76 N +ATOM 20414 CA THR K 180 69.358 47.675 43.575 1.00 62.10 C +ATOM 20415 C THR K 180 68.987 48.084 42.187 1.00 86.04 C +ATOM 20416 O THR K 180 69.868 48.242 41.342 1.00 84.88 O +ATOM 20417 CB THR K 180 70.260 48.820 44.092 1.00 62.41 C +ATOM 20418 OG1 THR K 180 71.017 48.368 45.209 1.00 83.67 O +ATOM 20419 CG2 THR K 180 69.467 50.067 44.457 1.00 52.68 C +ATOM 20420 N ILE K 181 67.731 48.490 42.027 1.00123.76 N +ATOM 20421 CA ILE K 181 67.242 49.030 40.758 1.00115.59 C +ATOM 20422 C ILE K 181 67.125 50.567 40.794 1.00117.63 C +ATOM 20423 O ILE K 181 66.358 51.126 41.588 1.00153.27 O +ATOM 20424 CB ILE K 181 65.872 48.407 40.396 1.00101.55 C +ATOM 20425 CG1 ILE K 181 65.951 46.884 40.474 1.00102.82 C +ATOM 20426 CG2 ILE K 181 65.441 48.815 39.003 1.00123.21 C +ATOM 20427 CD1 ILE K 181 65.000 46.284 41.480 1.00113.82 C +ATOM 20428 N LEU K 182 67.909 51.232 39.950 1.00 92.37 N +ATOM 20429 CA LEU K 182 67.966 52.684 39.921 1.00 88.52 C +ATOM 20430 C LEU K 182 66.987 53.298 38.926 1.00 89.50 C +ATOM 20431 O LEU K 182 66.873 52.851 37.780 1.00 82.17 O +ATOM 20432 CB LEU K 182 69.389 53.137 39.585 1.00 93.03 C +ATOM 20433 CG LEU K 182 69.604 54.651 39.483 1.00 89.35 C +ATOM 20434 CD1 LEU K 182 69.312 55.392 40.792 1.00 82.54 C +ATOM 20435 CD2 LEU K 182 71.028 54.888 39.016 1.00 82.99 C +ATOM 20436 N SER K 183 66.377 54.406 39.338 1.00105.94 N +ATOM 20437 CA SER K 183 65.551 55.215 38.453 1.00150.38 C +ATOM 20438 C SER K 183 65.807 56.707 38.695 1.00157.89 C +ATOM 20439 O SER K 183 65.965 57.137 39.837 1.00161.15 O +ATOM 20440 CB SER K 183 64.072 54.892 38.686 1.00158.20 C +ATOM 20441 OG SER K 183 63.896 53.504 38.930 1.00146.67 O +ATOM 20442 N TYR K 184 65.843 57.493 37.619 1.00137.79 N +ATOM 20443 CA TYR K 184 65.979 58.946 37.746 1.00112.55 C +ATOM 20444 C TYR K 184 65.352 59.753 36.613 1.00102.09 C +ATOM 20445 O TYR K 184 65.135 59.264 35.498 1.00118.99 O +ATOM 20446 CB TYR K 184 67.444 59.347 37.903 1.00 87.21 C +ATOM 20447 CG TYR K 184 68.318 58.918 36.755 1.00 76.52 C +ATOM 20448 CD1 TYR K 184 68.459 59.705 35.625 1.00 63.29 C +ATOM 20449 CD2 TYR K 184 68.992 57.699 36.793 1.00 87.16 C +ATOM 20450 CE1 TYR K 184 69.255 59.300 34.566 1.00 62.90 C +ATOM 20451 CE2 TYR K 184 69.831 57.303 35.758 1.00 84.57 C +ATOM 20452 CZ TYR K 184 69.977 58.117 34.652 1.00 73.87 C +ATOM 20453 OH TYR K 184 70.772 57.687 33.607 1.00 53.68 O +ATOM 20454 N GLU K 185 65.030 60.995 36.951 1.00108.00 N +ATOM 20455 CA GLU K 185 64.289 61.890 36.101 1.00129.40 C +ATOM 20456 C GLU K 185 64.905 63.276 36.116 1.00154.11 C +ATOM 20457 O GLU K 185 64.863 63.973 37.116 1.00166.52 O +ATOM 20458 CB GLU K 185 62.831 61.903 36.560 1.00131.25 C +ATOM 20459 CG GLU K 185 61.921 62.934 35.927 1.00140.55 C +ATOM 20460 CD GLU K 185 60.465 62.677 36.280 1.00145.13 C +ATOM 20461 OE1 GLU K 185 60.177 61.668 36.961 1.00148.77 O +ATOM 20462 OE2 GLU K 185 59.603 63.472 35.864 1.00156.57 O +ATOM 20463 N VAL K 186 65.545 63.631 35.007 1.00168.58 N +ATOM 20464 CA VAL K 186 66.184 64.928 34.849 1.00141.07 C +ATOM 20465 C VAL K 186 65.292 65.815 34.000 1.00148.56 C +ATOM 20466 O VAL K 186 64.691 65.374 33.016 1.00167.45 O +ATOM 20467 CB VAL K 186 67.566 64.804 34.181 1.00112.47 C +ATOM 20468 CG1 VAL K 186 68.282 66.140 34.206 1.00109.83 C +ATOM 20469 CG2 VAL K 186 68.398 63.743 34.877 1.00107.43 C +ATOM 20470 N GLN K 187 65.182 67.070 34.395 1.00136.59 N +ATOM 20471 CA GLN K 187 64.273 67.947 33.717 1.00150.37 C +ATOM 20472 C GLN K 187 64.766 69.405 33.784 1.00175.30 C +ATOM 20473 O GLN K 187 65.303 69.863 34.801 1.00223.74 O +ATOM 20474 CB GLN K 187 62.873 67.718 34.259 1.00131.78 C +ATOM 20475 CG GLN K 187 61.854 68.692 33.705 1.00135.57 C +ATOM 20476 CD GLN K 187 60.520 68.687 34.480 1.00135.34 C +ATOM 20477 OE1 GLN K 187 59.520 69.355 34.126 1.00139.89 O +ATOM 20478 NE2 GLN K 187 60.512 67.934 35.558 1.00142.81 N +ATOM 20479 N ALA K 188 64.716 70.088 32.645 1.00192.10 N +ATOM 20480 CA ALA K 188 65.171 71.473 32.570 1.00177.44 C +ATOM 20481 C ALA K 188 64.209 72.286 31.705 1.00166.03 C +ATOM 20482 O ALA K 188 63.721 71.808 30.697 1.00161.51 O +ATOM 20483 CB ALA K 188 66.596 71.546 32.036 1.00141.22 C +ATOM 20484 N GLY K 189 63.909 73.503 32.130 1.00144.81 N +ATOM 20485 CA GLY K 189 62.998 74.361 31.401 1.00144.08 C +ATOM 20486 C GLY K 189 63.444 75.808 31.414 1.00171.46 C +ATOM 20487 O GLY K 189 63.868 76.329 32.443 1.00195.48 O +ATOM 20488 N VAL K 190 63.325 76.465 30.267 1.00181.00 N +ATOM 20489 CA VAL K 190 63.620 77.881 30.162 1.00165.55 C +ATOM 20490 C VAL K 190 62.317 78.654 29.883 1.00165.56 C +ATOM 20491 O VAL K 190 61.503 78.247 29.050 1.00168.54 O +ATOM 20492 CB VAL K 190 64.666 78.142 29.059 1.00122.25 C +ATOM 20493 CG1 VAL K 190 65.145 79.586 29.134 1.00121.88 C +ATOM 20494 CG2 VAL K 190 65.826 77.155 29.174 1.00 83.53 C +ATOM 20495 N PHE K 191 62.124 79.772 30.581 1.00152.61 N +ATOM 20496 CA PHE K 191 60.850 80.491 30.538 1.00147.51 C +ATOM 20497 C PHE K 191 61.083 81.992 30.355 1.00157.85 C +ATOM 20498 O PHE K 191 61.908 82.588 31.056 1.00182.92 O +ATOM 20499 CB PHE K 191 60.063 80.227 31.827 1.00152.03 C +ATOM 20500 CG PHE K 191 58.587 80.465 31.700 1.00148.72 C +ATOM 20501 CD1 PHE K 191 58.083 81.757 31.623 1.00151.97 C +ATOM 20502 CD2 PHE K 191 57.696 79.399 31.686 1.00163.55 C +ATOM 20503 CE1 PHE K 191 56.717 81.984 31.527 1.00145.23 C +ATOM 20504 CE2 PHE K 191 56.330 79.619 31.585 1.00171.51 C +ATOM 20505 CZ PHE K 191 55.839 80.914 31.511 1.00148.23 C +ATOM 20506 N LEU K 200 58.328 83.048 25.457 1.00119.38 N +ATOM 20507 CA LEU K 200 59.242 81.936 25.255 1.00159.68 C +ATOM 20508 C LEU K 200 59.163 80.953 26.416 1.00214.24 C +ATOM 20509 O LEU K 200 59.596 81.265 27.532 1.00267.83 O +ATOM 20510 CB LEU K 200 60.701 82.414 25.096 1.00140.35 C +ATOM 20511 CG LEU K 200 61.755 81.279 25.079 1.00121.49 C +ATOM 20512 CD1 LEU K 200 62.183 80.971 23.657 1.00107.58 C +ATOM 20513 CD2 LEU K 200 62.963 81.567 25.973 1.00111.55 C +ATOM 20514 N GLU K 201 58.672 79.747 26.131 1.00242.48 N +ATOM 20515 CA GLU K 201 58.925 78.584 26.982 1.00229.82 C +ATOM 20516 C GLU K 201 59.646 77.490 26.204 1.00223.99 C +ATOM 20517 O GLU K 201 59.463 77.354 24.992 1.00267.89 O +ATOM 20518 CB GLU K 201 57.626 78.025 27.540 1.00197.94 C +ATOM 20519 CG GLU K 201 57.842 77.153 28.765 1.00192.63 C +ATOM 20520 CD GLU K 201 56.552 76.596 29.336 1.00217.87 C +ATOM 20521 OE1 GLU K 201 55.599 77.377 29.556 1.00264.01 O +ATOM 20522 OE2 GLU K 201 56.486 75.371 29.570 1.00221.96 O +ATOM 20523 N GLY K 202 60.511 76.751 26.893 1.00200.97 N +ATOM 20524 CA GLY K 202 61.195 75.611 26.292 1.00196.80 C +ATOM 20525 C GLY K 202 61.572 74.589 27.344 1.00201.09 C +ATOM 20526 O GLY K 202 62.220 74.918 28.336 1.00245.26 O +ATOM 20527 N GLU K 203 61.166 73.339 27.141 1.00187.39 N +ATOM 20528 CA GLU K 203 61.408 72.297 28.141 1.00150.72 C +ATOM 20529 C GLU K 203 62.065 71.045 27.570 1.00145.03 C +ATOM 20530 O GLU K 203 61.704 70.568 26.497 1.00147.14 O +ATOM 20531 CB GLU K 203 60.107 71.935 28.831 1.00144.38 C +ATOM 20532 CG GLU K 203 59.548 73.074 29.682 1.00171.43 C +ATOM 20533 CD GLU K 203 58.307 72.704 30.482 1.00198.82 C +ATOM 20534 OE1 GLU K 203 57.732 71.625 30.233 1.00249.08 O +ATOM 20535 OE2 GLU K 203 57.865 73.528 31.321 1.00207.71 O +ATOM 20536 N VAL K 204 63.068 70.555 28.289 1.00132.46 N +ATOM 20537 CA VAL K 204 63.705 69.285 28.000 1.00134.84 C +ATOM 20538 C VAL K 204 63.546 68.383 29.218 1.00169.20 C +ATOM 20539 O VAL K 204 63.723 68.819 30.352 1.00191.89 O +ATOM 20540 CB VAL K 204 65.200 69.466 27.646 1.00 90.57 C +ATOM 20541 CG1 VAL K 204 65.953 68.137 27.718 1.00 82.80 C +ATOM 20542 CG2 VAL K 204 65.317 70.082 26.261 1.00 88.58 C +ATOM 20543 N GLY K 205 63.166 67.134 28.971 1.00194.68 N +ATOM 20544 CA GLY K 205 63.041 66.144 30.029 1.00182.44 C +ATOM 20545 C GLY K 205 63.649 64.810 29.617 1.00178.11 C +ATOM 20546 O GLY K 205 63.652 64.452 28.434 1.00232.18 O +ATOM 20547 N TYR K 206 64.176 64.078 30.590 1.00131.92 N +ATOM 20548 CA TYR K 206 64.700 62.731 30.357 1.00 96.31 C +ATOM 20549 C TYR K 206 64.495 61.874 31.582 1.00105.72 C +ATOM 20550 O TYR K 206 64.623 62.354 32.698 1.00114.76 O +ATOM 20551 CB TYR K 206 66.184 62.774 30.041 1.00 78.56 C +ATOM 20552 CG TYR K 206 66.799 61.402 29.872 1.00 71.38 C +ATOM 20553 CD1 TYR K 206 66.619 60.675 28.694 1.00 82.07 C +ATOM 20554 CD2 TYR K 206 67.581 60.842 30.876 1.00 74.19 C +ATOM 20555 CE1 TYR K 206 67.219 59.438 28.518 1.00101.69 C +ATOM 20556 CE2 TYR K 206 68.183 59.607 30.718 1.00 81.01 C +ATOM 20557 CZ TYR K 206 68.012 58.912 29.539 1.00107.31 C +ATOM 20558 OH TYR K 206 68.616 57.683 29.380 1.00125.25 O +ATOM 20559 N THR K 207 64.138 60.608 31.378 1.00117.65 N +ATOM 20560 CA THR K 207 63.921 59.674 32.494 1.00 99.23 C +ATOM 20561 C THR K 207 64.513 58.300 32.184 1.00 87.19 C +ATOM 20562 O THR K 207 64.403 57.798 31.059 1.00 81.65 O +ATOM 20563 CB THR K 207 62.426 59.490 32.814 1.00 87.24 C +ATOM 20564 OG1 THR K 207 61.759 58.927 31.679 1.00121.83 O +ATOM 20565 CG2 THR K 207 61.771 60.811 33.152 1.00 83.35 C +ATOM 20566 N SER K 208 65.198 57.724 33.159 1.00 90.48 N +ATOM 20567 CA SER K 208 65.829 56.427 32.956 1.00 91.97 C +ATOM 20568 C SER K 208 65.542 55.486 34.110 1.00111.42 C +ATOM 20569 O SER K 208 65.814 55.801 35.269 1.00134.75 O +ATOM 20570 CB SER K 208 67.343 56.552 32.748 1.00 82.19 C +ATOM 20571 OG SER K 208 67.952 55.259 32.703 1.00 67.95 O +ATOM 20572 N ASN K 209 65.015 54.314 33.767 1.00120.60 N +ATOM 20573 CA ASN K 209 64.826 53.219 34.710 1.00104.55 C +ATOM 20574 C ASN K 209 65.747 52.075 34.364 1.00 96.33 C +ATOM 20575 O ASN K 209 65.857 51.687 33.201 1.00120.63 O +ATOM 20576 CB ASN K 209 63.388 52.729 34.660 1.00 94.37 C +ATOM 20577 CG ASN K 209 62.433 53.749 35.218 1.00 92.80 C +ATOM 20578 OD1 ASN K 209 62.202 53.799 36.419 1.00112.07 O +ATOM 20579 ND2 ASN K 209 61.817 54.517 34.341 1.00 96.92 N +ATOM 20580 N GLU K 210 66.363 51.500 35.379 1.00 77.50 N +ATOM 20581 CA GLU K 210 67.005 50.217 35.196 1.00 92.37 C +ATOM 20582 C GLU K 210 65.943 49.160 34.911 1.00 82.13 C +ATOM 20583 O GLU K 210 64.852 49.169 35.496 1.00 75.04 O +ATOM 20584 CB GLU K 210 67.794 49.840 36.451 1.00121.43 C +ATOM 20585 CG GLU K 210 69.183 49.286 36.201 1.00128.79 C +ATOM 20586 CD GLU K 210 70.059 49.327 37.453 1.00139.10 C +ATOM 20587 OE1 GLU K 210 69.863 50.205 38.340 1.00 96.83 O +ATOM 20588 OE2 GLU K 210 71.005 48.518 37.499 1.00185.55 O +ATOM 20589 N PRO K 211 66.277 48.209 34.057 1.00 83.03 N +ATOM 20590 CA PRO K 211 65.367 47.088 33.904 1.00127.13 C +ATOM 20591 C PRO K 211 65.441 46.123 35.094 1.00127.54 C +ATOM 20592 O PRO K 211 66.521 45.632 35.418 1.00 82.55 O +ATOM 20593 CB PRO K 211 65.856 46.411 32.608 1.00157.34 C +ATOM 20594 CG PRO K 211 66.697 47.440 31.918 1.00128.53 C +ATOM 20595 CD PRO K 211 67.325 48.212 33.036 1.00 90.39 C +ATOM 20596 N VAL K 212 64.282 45.830 35.690 1.00131.73 N +ATOM 20597 CA VAL K 212 64.185 44.886 36.801 1.00108.14 C +ATOM 20598 C VAL K 212 64.571 43.489 36.328 1.00 97.36 C +ATOM 20599 O VAL K 212 65.312 42.764 36.993 1.00102.66 O +ATOM 20600 CB VAL K 212 62.754 44.813 37.353 1.00102.37 C +ATOM 20601 CG1 VAL K 212 62.729 43.947 38.600 1.00106.50 C +ATOM 20602 CG2 VAL K 212 62.212 46.209 37.663 1.00128.87 C +ATOM 20603 N MET K 213 64.076 43.159 35.148 1.00 80.63 N +ATOM 20604 CA MET K 213 64.569 42.069 34.315 1.00 84.93 C +ATOM 20605 C MET K 213 66.086 41.819 34.387 1.00 84.88 C +ATOM 20606 O MET K 213 66.560 40.698 34.660 1.00 89.97 O +ATOM 20607 CB MET K 213 64.171 42.465 32.893 1.00 95.77 C +ATOM 20608 CG MET K 213 64.414 41.472 31.789 1.00119.34 C +ATOM 20609 SD MET K 213 63.798 42.274 30.273 1.00132.00 S +ATOM 20610 CE MET K 213 65.412 42.480 29.517 1.00184.19 C +ATOM 20611 N LEU K 214 66.843 42.893 34.202 1.00 89.58 N +ATOM 20612 CA LEU K 214 68.283 42.805 33.988 1.00119.53 C +ATOM 20613 C LEU K 214 69.002 42.738 35.329 1.00136.83 C +ATOM 20614 O LEU K 214 70.067 42.125 35.454 1.00165.82 O +ATOM 20615 CB LEU K 214 68.768 44.027 33.196 1.00145.00 C +ATOM 20616 CG LEU K 214 69.781 43.833 32.061 1.00159.37 C +ATOM 20617 CD1 LEU K 214 69.244 42.895 30.977 1.00180.47 C +ATOM 20618 CD2 LEU K 214 70.151 45.186 31.462 1.00134.01 C +ATOM 20619 N CYS K 215 68.398 43.352 36.341 1.00121.98 N +ATOM 20620 CA CYS K 215 68.917 43.282 37.710 1.00112.56 C +ATOM 20621 C CYS K 215 68.740 41.879 38.312 1.00102.89 C +ATOM 20622 O CYS K 215 69.625 41.352 39.016 1.00 66.99 O +ATOM 20623 CB CYS K 215 68.186 44.281 38.597 1.00117.92 C +ATOM 20624 SG CYS K 215 68.450 45.988 38.120 1.00127.15 S +ATOM 20625 N LEU K 216 67.573 41.293 38.046 1.00 98.74 N +ATOM 20626 CA LEU K 216 67.315 39.925 38.431 1.00 92.36 C +ATOM 20627 C LEU K 216 68.384 39.015 37.826 1.00 86.46 C +ATOM 20628 O LEU K 216 69.000 38.210 38.544 1.00110.11 O +ATOM 20629 CB LEU K 216 65.921 39.486 37.985 1.00 73.41 C +ATOM 20630 CG LEU K 216 65.584 38.024 38.316 1.00 64.48 C +ATOM 20631 CD1 LEU K 216 65.664 37.720 39.797 1.00 60.83 C +ATOM 20632 CD2 LEU K 216 64.183 37.713 37.823 1.00 91.59 C +ATOM 20633 N MET K 217 68.657 39.211 36.538 1.00 67.45 N +ATOM 20634 CA MET K 217 69.581 38.350 35.833 1.00 86.99 C +ATOM 20635 C MET K 217 70.986 38.495 36.414 1.00112.15 C +ATOM 20636 O MET K 217 71.641 37.494 36.746 1.00181.67 O +ATOM 20637 CB MET K 217 69.588 38.655 34.343 1.00 87.75 C +ATOM 20638 CG MET K 217 69.602 37.396 33.469 1.00 87.07 C +ATOM 20639 SD MET K 217 71.175 36.505 33.559 1.00137.24 S +ATOM 20640 CE MET K 217 70.802 34.982 32.688 1.00 89.66 C +ATOM 20641 N SER K 218 71.404 39.735 36.631 1.00107.01 N +ATOM 20642 CA SER K 218 72.703 40.027 37.256 1.00101.56 C +ATOM 20643 C SER K 218 72.880 39.340 38.612 1.00 90.25 C +ATOM 20644 O SER K 218 73.879 38.674 38.866 1.00 60.65 O +ATOM 20645 CB SER K 218 72.858 41.543 37.440 1.00111.06 C +ATOM 20646 OG SER K 218 74.181 41.890 37.802 1.00 97.56 O +ATOM 20647 N ALA K 219 71.890 39.518 39.479 1.00 96.80 N +ATOM 20648 CA ALA K 219 71.967 38.990 40.824 1.00101.25 C +ATOM 20649 C ALA K 219 72.054 37.452 40.820 1.00 89.66 C +ATOM 20650 O ALA K 219 72.695 36.841 41.686 1.00 74.98 O +ATOM 20651 CB ALA K 219 70.767 39.485 41.630 1.00115.14 C +ATOM 20652 N ILE K 220 71.345 36.822 39.889 1.00 79.70 N +ATOM 20653 CA ILE K 220 71.349 35.361 39.801 1.00 80.81 C +ATOM 20654 C ILE K 220 72.738 34.855 39.386 1.00 83.93 C +ATOM 20655 O ILE K 220 73.239 33.875 39.940 1.00 68.01 O +ATOM 20656 CB ILE K 220 70.263 34.833 38.825 1.00 73.26 C +ATOM 20657 CG1 ILE K 220 68.857 35.079 39.416 1.00 64.68 C +ATOM 20658 CG2 ILE K 220 70.497 33.342 38.509 1.00 58.63 C +ATOM 20659 CD1 ILE K 220 67.730 34.981 38.419 1.00 49.55 C +ATOM 20660 N GLU K 221 73.366 35.556 38.445 1.00 99.29 N +ATOM 20661 CA GLU K 221 74.729 35.232 38.030 1.00110.01 C +ATOM 20662 C GLU K 221 75.670 35.299 39.243 1.00132.51 C +ATOM 20663 O GLU K 221 76.422 34.347 39.516 1.00128.60 O +ATOM 20664 CB GLU K 221 75.195 36.201 36.938 1.00 98.88 C +ATOM 20665 CG GLU K 221 74.563 35.938 35.586 1.00 92.18 C +ATOM 20666 CD GLU K 221 74.668 37.111 34.624 1.00101.48 C +ATOM 20667 OE1 GLU K 221 74.608 38.299 35.056 1.00118.81 O +ATOM 20668 OE2 GLU K 221 74.831 36.835 33.412 1.00 83.52 O +ATOM 20669 N THR K 222 75.599 36.419 39.970 1.00115.99 N +ATOM 20670 CA THR K 222 76.397 36.647 41.177 1.00 85.96 C +ATOM 20671 C THR K 222 76.227 35.503 42.170 1.00 84.02 C +ATOM 20672 O THR K 222 77.212 34.967 42.692 1.00 69.55 O +ATOM 20673 CB THR K 222 75.952 37.946 41.856 1.00 79.64 C +ATOM 20674 OG1 THR K 222 76.382 39.082 41.084 1.00 85.57 O +ATOM 20675 CG2 THR K 222 76.490 38.027 43.299 1.00 86.00 C +ATOM 20676 N GLY K 223 74.970 35.134 42.415 1.00 73.30 N +ATOM 20677 CA GLY K 223 74.655 33.978 43.244 1.00 75.97 C +ATOM 20678 C GLY K 223 75.308 32.672 42.784 1.00 78.01 C +ATOM 20679 O GLY K 223 75.812 31.894 43.607 1.00 79.81 O +ATOM 20680 N VAL K 224 75.331 32.441 41.474 1.00 72.01 N +ATOM 20681 CA VAL K 224 75.952 31.242 40.940 1.00 83.49 C +ATOM 20682 C VAL K 224 77.451 31.242 41.235 1.00 95.89 C +ATOM 20683 O VAL K 224 78.007 30.207 41.627 1.00121.01 O +ATOM 20684 CB VAL K 224 75.751 31.121 39.428 1.00109.43 C +ATOM 20685 CG1 VAL K 224 76.554 29.947 38.872 1.00108.90 C +ATOM 20686 CG2 VAL K 224 74.277 30.964 39.103 1.00117.49 C +ATOM 20687 N ILE K 225 78.098 32.396 41.080 1.00 82.45 N +ATOM 20688 CA ILE K 225 79.514 32.497 41.398 1.00 82.12 C +ATOM 20689 C ILE K 225 79.751 32.146 42.863 1.00 88.74 C +ATOM 20690 O ILE K 225 80.602 31.298 43.163 1.00 62.58 O +ATOM 20691 CB ILE K 225 80.078 33.895 41.093 1.00 94.54 C +ATOM 20692 CG1 ILE K 225 80.088 34.126 39.585 1.00125.78 C +ATOM 20693 CG2 ILE K 225 81.501 34.031 41.620 1.00 84.48 C +ATOM 20694 CD1 ILE K 225 80.218 35.583 39.190 1.00161.40 C +ATOM 20695 N PHE K 226 79.021 32.810 43.774 1.00 89.25 N +ATOM 20696 CA PHE K 226 79.158 32.551 45.229 1.00 88.31 C +ATOM 20697 C PHE K 226 78.937 31.060 45.574 1.00 77.81 C +ATOM 20698 O PHE K 226 79.574 30.528 46.471 1.00 55.86 O +ATOM 20699 CB PHE K 226 78.186 33.415 46.057 1.00 85.05 C +ATOM 20700 CG PHE K 226 78.632 34.839 46.284 1.00 97.70 C +ATOM 20701 CD1 PHE K 226 79.849 35.119 46.921 1.00131.12 C +ATOM 20702 CD2 PHE K 226 77.805 35.901 45.952 1.00 91.26 C +ATOM 20703 CE1 PHE K 226 80.278 36.434 47.125 1.00 95.91 C +ATOM 20704 CE2 PHE K 226 78.215 37.209 46.178 1.00101.80 C +ATOM 20705 CZ PHE K 226 79.459 37.473 46.761 1.00 95.27 C +ATOM 20706 N LEU K 227 78.033 30.412 44.852 1.00 71.24 N +ATOM 20707 CA LEU K 227 77.800 28.991 45.017 1.00 74.62 C +ATOM 20708 C LEU K 227 79.001 28.157 44.593 1.00 80.68 C +ATOM 20709 O LEU K 227 79.387 27.237 45.294 1.00 67.10 O +ATOM 20710 CB LEU K 227 76.584 28.591 44.199 1.00 94.19 C +ATOM 20711 CG LEU K 227 75.217 28.966 44.787 1.00 95.78 C +ATOM 20712 CD1 LEU K 227 74.035 28.822 43.839 1.00 81.27 C +ATOM 20713 CD2 LEU K 227 74.949 28.174 46.053 1.00109.92 C +ATOM 20714 N ILE K 228 79.615 28.507 43.463 1.00 96.25 N +ATOM 20715 CA ILE K 228 80.763 27.759 42.959 1.00106.05 C +ATOM 20716 C ILE K 228 81.922 27.939 43.916 1.00106.13 C +ATOM 20717 O ILE K 228 82.586 26.963 44.297 1.00107.44 O +ATOM 20718 CB ILE K 228 81.214 28.217 41.548 1.00107.91 C +ATOM 20719 CG1 ILE K 228 80.131 27.926 40.512 1.00114.55 C +ATOM 20720 CG2 ILE K 228 82.473 27.474 41.127 1.00 98.85 C +ATOM 20721 CD1 ILE K 228 80.309 28.646 39.196 1.00 97.42 C +ATOM 20722 N ASN K 229 82.170 29.187 44.301 1.00 77.54 N +ATOM 20723 CA ASN K 229 83.275 29.488 45.195 1.00 91.43 C +ATOM 20724 C ASN K 229 83.089 28.740 46.518 1.00 76.89 C +ATOM 20725 O ASN K 229 84.043 28.169 47.069 1.00 85.38 O +ATOM 20726 CB ASN K 229 83.371 31.015 45.408 1.00110.22 C +ATOM 20727 CG ASN K 229 84.719 31.473 45.968 1.00124.14 C +ATOM 20728 OD1 ASN K 229 85.717 30.750 45.891 1.00158.19 O +ATOM 20729 ND2 ASN K 229 84.730 32.655 46.589 1.00 96.53 N +ATOM 20730 N ASP K 230 81.874 28.790 47.040 1.00 56.20 N +ATOM 20731 CA ASP K 230 81.576 28.139 48.285 1.00 63.62 C +ATOM 20732 C ASP K 230 81.857 26.649 48.155 1.00 69.48 C +ATOM 20733 O ASP K 230 82.320 25.990 49.086 1.00 67.12 O +ATOM 20734 CB ASP K 230 80.119 28.395 48.658 1.00 84.08 C +ATOM 20735 CG ASP K 230 79.757 27.821 50.024 1.00115.16 C +ATOM 20736 OD1 ASP K 230 80.175 28.419 51.033 1.00133.62 O +ATOM 20737 OD2 ASP K 230 78.999 26.819 50.090 1.00189.02 O +ATOM 20738 N GLY K 231 81.462 26.082 47.025 1.00108.26 N +ATOM 20739 CA GLY K 231 81.601 24.644 46.808 1.00128.20 C +ATOM 20740 C GLY K 231 83.071 24.275 46.728 1.00107.48 C +ATOM 20741 O GLY K 231 83.458 23.158 47.114 1.00 98.81 O +ATOM 20742 N ILE K 232 83.869 25.190 46.171 1.00 78.33 N +ATOM 20743 CA ILE K 232 85.295 24.961 46.047 1.00100.46 C +ATOM 20744 C ILE K 232 85.869 24.857 47.449 1.00122.70 C +ATOM 20745 O ILE K 232 86.624 23.922 47.743 1.00129.27 O +ATOM 20746 CB ILE K 232 85.990 26.092 45.256 1.00115.30 C +ATOM 20747 CG1 ILE K 232 85.690 25.943 43.763 1.00121.80 C +ATOM 20748 CG2 ILE K 232 87.508 26.098 45.496 1.00137.33 C +ATOM 20749 CD1 ILE K 232 85.949 27.197 42.951 1.00123.24 C +ATOM 20750 N ASP K 233 85.530 25.830 48.296 1.00137.08 N +ATOM 20751 CA ASP K 233 85.989 25.855 49.690 1.00149.59 C +ATOM 20752 C ASP K 233 85.595 24.583 50.435 1.00142.55 C +ATOM 20753 O ASP K 233 86.432 23.942 51.068 1.00176.09 O +ATOM 20754 CB ASP K 233 85.405 27.062 50.432 1.00150.88 C +ATOM 20755 CG ASP K 233 85.912 28.404 49.896 1.00151.27 C +ATOM 20756 OD1 ASP K 233 86.575 28.424 48.836 1.00139.05 O +ATOM 20757 OD2 ASP K 233 85.636 29.442 50.546 1.00129.43 O +ATOM 20758 N ARG K 234 84.334 24.200 50.311 1.00138.25 N +ATOM 20759 CA ARG K 234 83.810 23.066 51.052 1.00156.87 C +ATOM 20760 C ARG K 234 84.129 21.685 50.455 1.00178.28 C +ATOM 20761 O ARG K 234 83.740 20.650 51.018 1.00240.88 O +ATOM 20762 CB ARG K 234 82.304 23.227 51.211 1.00172.86 C +ATOM 20763 CG ARG K 234 81.968 24.325 52.194 1.00156.31 C +ATOM 20764 CD ARG K 234 80.568 24.866 52.005 1.00162.33 C +ATOM 20765 NE ARG K 234 80.386 25.968 52.946 1.00148.37 N +ATOM 20766 CZ ARG K 234 79.442 26.018 53.876 1.00164.26 C +ATOM 20767 NH1 ARG K 234 78.518 25.052 53.928 1.00207.56 N +ATOM 20768 NH2 ARG K 234 79.405 27.030 54.745 1.00107.74 N +ATOM 20769 N GLY K 235 84.823 21.658 49.324 1.00167.26 N +ATOM 20770 CA GLY K 235 85.246 20.399 48.716 1.00140.19 C +ATOM 20771 C GLY K 235 84.135 19.648 48.008 1.00 97.08 C +ATOM 20772 O GLY K 235 84.143 18.419 47.974 1.00 56.83 O +ATOM 20773 N LEU K 236 83.179 20.384 47.440 1.00 98.07 N +ATOM 20774 CA LEU K 236 82.194 19.767 46.547 1.00118.18 C +ATOM 20775 C LEU K 236 82.884 19.448 45.227 1.00110.86 C +ATOM 20776 O LEU K 236 82.741 18.338 44.697 1.00141.17 O +ATOM 20777 CB LEU K 236 80.970 20.677 46.295 1.00122.44 C +ATOM 20778 CG LEU K 236 79.846 20.671 47.332 1.00108.67 C +ATOM 20779 CD1 LEU K 236 80.211 21.514 48.549 1.00109.57 C +ATOM 20780 CD2 LEU K 236 78.564 21.190 46.712 1.00 94.76 C +ATOM 20781 N TRP K 237 83.612 20.426 44.693 1.00 81.73 N +ATOM 20782 CA TRP K 237 84.255 20.282 43.390 1.00 88.33 C +ATOM 20783 C TRP K 237 85.623 20.938 43.419 1.00108.74 C +ATOM 20784 O TRP K 237 85.932 21.693 44.343 1.00106.11 O +ATOM 20785 CB TRP K 237 83.389 20.878 42.275 1.00 84.96 C +ATOM 20786 CG TRP K 237 82.599 22.054 42.713 1.00 97.02 C +ATOM 20787 CD1 TRP K 237 83.085 23.276 43.048 1.00110.25 C +ATOM 20788 CD2 TRP K 237 81.169 22.135 42.863 1.00121.44 C +ATOM 20789 NE1 TRP K 237 82.054 24.129 43.380 1.00106.24 N +ATOM 20790 CE2 TRP K 237 80.868 23.457 43.272 1.00121.07 C +ATOM 20791 CE3 TRP K 237 80.119 21.224 42.693 1.00127.56 C +ATOM 20792 CZ2 TRP K 237 79.567 23.887 43.523 1.00133.53 C +ATOM 20793 CZ3 TRP K 237 78.823 21.653 42.948 1.00136.45 C +ATOM 20794 CH2 TRP K 237 78.562 22.975 43.355 1.00153.49 C +ATOM 20795 N ASP K 238 86.456 20.606 42.434 1.00131.61 N +ATOM 20796 CA ASP K 238 87.864 21.008 42.444 1.00135.33 C +ATOM 20797 C ASP K 238 88.294 21.675 41.147 1.00128.31 C +ATOM 20798 O ASP K 238 87.822 21.323 40.055 1.00112.81 O +ATOM 20799 CB ASP K 238 88.781 19.811 42.721 1.00123.52 C +ATOM 20800 CG ASP K 238 88.449 19.108 44.023 1.00122.41 C +ATOM 20801 OD1 ASP K 238 87.485 18.315 44.025 1.00 99.42 O +ATOM 20802 OD2 ASP K 238 89.134 19.351 45.045 1.00113.35 O +ATOM 20803 N LEU K 239 89.236 22.608 41.274 1.00126.25 N +ATOM 20804 CA LEU K 239 89.760 23.340 40.130 1.00137.98 C +ATOM 20805 C LEU K 239 90.730 22.475 39.328 1.00140.48 C +ATOM 20806 O LEU K 239 91.471 21.672 39.891 1.00102.09 O +ATOM 20807 CB LEU K 239 90.474 24.622 40.584 1.00129.26 C +ATOM 20808 CG LEU K 239 89.654 25.835 41.020 1.00126.10 C +ATOM 20809 CD1 LEU K 239 90.560 27.021 41.324 1.00138.21 C +ATOM 20810 CD2 LEU K 239 88.652 26.215 39.950 1.00143.36 C +ATOM 20811 N GLN K 240 90.705 22.653 38.009 1.00143.36 N +ATOM 20812 CA GLN K 240 91.709 22.070 37.138 1.00129.49 C +ATOM 20813 C GLN K 240 93.106 22.459 37.626 1.00133.90 C +ATOM 20814 O GLN K 240 93.947 21.600 37.900 1.00129.52 O +ATOM 20815 CB GLN K 240 91.494 22.539 35.688 1.00125.64 C +ATOM 20816 CG GLN K 240 92.375 21.825 34.669 1.00125.77 C +ATOM 20817 CD GLN K 240 92.050 20.345 34.570 1.00134.73 C +ATOM 20818 OE1 GLN K 240 91.085 19.954 33.910 1.00145.27 O +ATOM 20819 NE2 GLN K 240 92.822 19.515 35.271 1.00136.97 N +ATOM 20820 N ASN K 241 93.338 23.766 37.716 1.00151.94 N +ATOM 20821 CA ASN K 241 94.612 24.319 38.166 1.00153.12 C +ATOM 20822 C ASN K 241 94.502 24.847 39.583 1.00134.51 C +ATOM 20823 O ASN K 241 93.869 25.881 39.819 1.00111.23 O +ATOM 20824 CB ASN K 241 95.043 25.463 37.248 1.00166.41 C +ATOM 20825 CG ASN K 241 96.089 25.037 36.244 1.00197.03 C +ATOM 20826 OD1 ASN K 241 97.271 25.319 36.426 1.00187.68 O +ATOM 20827 ND2 ASN K 241 95.666 24.341 35.187 1.00217.43 N +ATOM 20828 N LYS K 242 95.146 24.150 40.516 1.00125.81 N +ATOM 20829 CA LYS K 242 95.128 24.556 41.917 1.00109.65 C +ATOM 20830 C LYS K 242 95.828 25.904 42.074 1.00125.88 C +ATOM 20831 O LYS K 242 95.518 26.678 42.988 1.00 90.22 O +ATOM 20832 CB LYS K 242 95.786 23.487 42.790 1.00110.62 C +ATOM 20833 CG LYS K 242 95.280 22.075 42.519 1.00120.72 C +ATOM 20834 CD LYS K 242 94.780 21.398 43.784 1.00148.31 C +ATOM 20835 CE LYS K 242 93.433 20.728 43.552 1.00166.62 C +ATOM 20836 NZ LYS K 242 92.982 19.925 44.722 1.00170.51 N +ATOM 20837 N ALA K 243 96.741 26.179 41.134 1.00159.15 N +ATOM 20838 CA ALA K 243 97.432 27.463 41.024 1.00160.48 C +ATOM 20839 C ALA K 243 96.460 28.604 40.747 1.00176.13 C +ATOM 20840 O ALA K 243 96.797 29.773 40.967 1.00175.84 O +ATOM 20841 CB ALA K 243 98.485 27.404 39.920 1.00142.53 C +ATOM 20842 N GLU K 244 95.266 28.274 40.248 1.00177.08 N +ATOM 20843 CA GLU K 244 94.285 29.302 39.913 1.00173.38 C +ATOM 20844 C GLU K 244 93.326 29.599 41.063 1.00159.04 C +ATOM 20845 O GLU K 244 92.345 30.298 40.862 1.00140.74 O +ATOM 20846 CB GLU K 244 93.492 28.912 38.665 1.00150.74 C +ATOM 20847 CG GLU K 244 94.283 29.010 37.377 1.00152.41 C +ATOM 20848 CD GLU K 244 93.405 28.878 36.148 1.00164.04 C +ATOM 20849 OE1 GLU K 244 93.015 27.737 35.809 1.00164.38 O +ATOM 20850 OE2 GLU K 244 93.140 29.913 35.494 1.00174.14 O +ATOM 20851 N ARG K 245 93.620 29.091 42.258 1.00139.22 N +ATOM 20852 CA ARG K 245 92.838 29.438 43.435 1.00131.66 C +ATOM 20853 C ARG K 245 92.785 30.947 43.677 1.00134.85 C +ATOM 20854 O ARG K 245 91.766 31.457 44.159 1.00173.38 O +ATOM 20855 CB ARG K 245 93.365 28.753 44.688 1.00139.04 C +ATOM 20856 CG ARG K 245 92.459 28.939 45.908 1.00143.49 C +ATOM 20857 CD ARG K 245 92.941 28.160 47.138 1.00180.04 C +ATOM 20858 NE ARG K 245 92.226 26.887 47.267 1.00228.43 N +ATOM 20859 CZ ARG K 245 90.951 26.763 47.635 1.00213.02 C +ATOM 20860 NH1 ARG K 245 90.221 27.830 47.888 1.00176.49 N +ATOM 20861 NH2 ARG K 245 90.399 25.559 47.747 1.00219.98 N +ATOM 20862 N GLN K 246 93.889 31.650 43.412 1.00113.56 N +ATOM 20863 CA GLN K 246 93.963 33.082 43.725 1.00116.99 C +ATOM 20864 C GLN K 246 93.553 33.925 42.533 1.00110.05 C +ATOM 20865 O GLN K 246 93.929 35.093 42.427 1.00114.97 O +ATOM 20866 CB GLN K 246 95.364 33.481 44.212 1.00125.45 C +ATOM 20867 CG GLN K 246 95.711 32.984 45.608 1.00153.95 C +ATOM 20868 CD GLN K 246 96.032 31.504 45.624 1.00186.23 C +ATOM 20869 OE1 GLN K 246 96.784 31.013 44.777 1.00188.04 O +ATOM 20870 NE2 GLN K 246 95.502 30.792 46.615 1.00216.77 N +ATOM 20871 N ASN K 247 92.800 33.314 41.622 1.00111.89 N +ATOM 20872 CA ASN K 247 92.144 34.027 40.520 1.00117.92 C +ATOM 20873 C ASN K 247 91.526 35.337 41.004 1.00112.94 C +ATOM 20874 O ASN K 247 90.906 35.374 42.073 1.00129.26 O +ATOM 20875 CB ASN K 247 91.054 33.128 39.928 1.00122.10 C +ATOM 20876 CG ASN K 247 90.740 33.454 38.494 1.00134.39 C +ATOM 20877 OD1 ASN K 247 89.680 34.012 38.187 1.00137.90 O +ATOM 20878 ND2 ASN K 247 91.666 33.120 37.602 1.00140.97 N +ATOM 20879 N ASP K 248 91.669 36.395 40.211 1.00120.36 N +ATOM 20880 CA ASP K 248 91.151 37.727 40.580 1.00150.19 C +ATOM 20881 C ASP K 248 89.671 37.681 40.976 1.00153.85 C +ATOM 20882 O ASP K 248 89.251 38.270 41.983 1.00133.95 O +ATOM 20883 CB ASP K 248 91.312 38.709 39.410 1.00166.07 C +ATOM 20884 CG ASP K 248 92.762 39.091 39.152 1.00169.27 C +ATOM 20885 OD1 ASP K 248 93.524 39.275 40.121 1.00141.16 O +ATOM 20886 OD2 ASP K 248 93.123 39.251 37.969 1.00199.84 O +ATOM 20887 N ILE K 249 88.884 36.993 40.153 1.00164.45 N +ATOM 20888 CA ILE K 249 87.443 36.914 40.338 1.00150.29 C +ATOM 20889 C ILE K 249 87.121 36.131 41.616 1.00140.28 C +ATOM 20890 O ILE K 249 86.368 36.600 42.478 1.00184.38 O +ATOM 20891 CB ILE K 249 86.774 36.245 39.119 1.00142.25 C +ATOM 20892 CG1 ILE K 249 86.994 37.088 37.855 1.00133.24 C +ATOM 20893 CG2 ILE K 249 85.287 36.075 39.363 1.00154.34 C +ATOM 20894 CD1 ILE K 249 86.817 36.321 36.563 1.00125.62 C +ATOM 20895 N LEU K 250 87.732 34.957 41.749 1.00112.40 N +ATOM 20896 CA LEU K 250 87.506 34.094 42.912 1.00108.44 C +ATOM 20897 C LEU K 250 87.860 34.761 44.244 1.00126.04 C +ATOM 20898 O LEU K 250 87.154 34.577 45.236 1.00155.51 O +ATOM 20899 CB LEU K 250 88.291 32.793 42.777 1.00106.68 C +ATOM 20900 CG LEU K 250 87.662 31.751 41.853 1.00109.82 C +ATOM 20901 CD1 LEU K 250 88.626 30.619 41.536 1.00104.28 C +ATOM 20902 CD2 LEU K 250 86.400 31.200 42.480 1.00118.23 C +ATOM 20903 N VAL K 251 88.945 35.534 44.264 1.00131.05 N +ATOM 20904 CA VAL K 251 89.338 36.253 45.477 1.00135.69 C +ATOM 20905 C VAL K 251 88.457 37.485 45.724 1.00146.25 C +ATOM 20906 O VAL K 251 88.321 37.945 46.864 1.00178.38 O +ATOM 20907 CB VAL K 251 90.822 36.675 45.454 1.00140.92 C +ATOM 20908 CG1 VAL K 251 91.712 35.464 45.207 1.00133.37 C +ATOM 20909 CG2 VAL K 251 91.079 37.776 44.424 1.00133.27 C +ATOM 20910 N LYS K 252 87.876 38.027 44.656 1.00125.04 N +ATOM 20911 CA LYS K 252 86.948 39.151 44.774 1.00107.30 C +ATOM 20912 C LYS K 252 85.663 38.707 45.494 1.00124.41 C +ATOM 20913 O LYS K 252 85.205 39.365 46.436 1.00143.42 O +ATOM 20914 CB LYS K 252 86.653 39.702 43.384 1.00103.68 C +ATOM 20915 CG LYS K 252 85.672 40.854 43.340 1.00113.15 C +ATOM 20916 CD LYS K 252 85.438 41.286 41.890 1.00133.43 C +ATOM 20917 CE LYS K 252 83.952 41.454 41.571 1.00140.01 C +ATOM 20918 NZ LYS K 252 83.673 41.620 40.111 1.00107.86 N +ATOM 20919 N TYR K 253 85.126 37.550 45.096 1.00151.57 N +ATOM 20920 CA TYR K 253 83.883 37.003 45.689 1.00134.01 C +ATOM 20921 C TYR K 253 84.156 36.348 47.032 1.00124.17 C +ATOM 20922 O TYR K 253 83.329 36.401 47.935 1.00130.98 O +ATOM 20923 CB TYR K 253 83.206 36.001 44.738 1.00113.90 C +ATOM 20924 CG TYR K 253 82.564 36.667 43.541 1.00110.72 C +ATOM 20925 CD1 TYR K 253 81.309 37.247 43.635 1.00106.95 C +ATOM 20926 CD2 TYR K 253 83.264 36.827 42.346 1.00123.24 C +ATOM 20927 CE1 TYR K 253 80.749 37.920 42.558 1.00109.58 C +ATOM 20928 CE2 TYR K 253 82.716 37.524 41.275 1.00131.62 C +ATOM 20929 CZ TYR K 253 81.446 38.058 41.388 1.00116.76 C +ATOM 20930 OH TYR K 253 80.899 38.760 40.327 1.00112.49 O +ATOM 20931 N ARG K 254 85.348 35.778 47.173 1.00115.51 N +ATOM 20932 CA ARG K 254 85.837 35.340 48.476 1.00106.05 C +ATOM 20933 C ARG K 254 85.834 36.513 49.462 1.00 98.49 C +ATOM 20934 O ARG K 254 85.512 36.350 50.643 1.00 93.04 O +ATOM 20935 CB ARG K 254 87.257 34.751 48.358 1.00109.31 C +ATOM 20936 CG ARG K 254 87.779 34.148 49.649 1.00 98.30 C +ATOM 20937 CD ARG K 254 88.957 33.219 49.433 1.00 94.49 C +ATOM 20938 NE ARG K 254 88.610 32.021 48.682 1.00 99.00 N +ATOM 20939 CZ ARG K 254 88.975 31.774 47.429 1.00142.21 C +ATOM 20940 NH1 ARG K 254 89.702 32.647 46.741 1.00142.60 N +ATOM 20941 NH2 ARG K 254 88.616 30.629 46.852 1.00166.93 N +ATOM 20942 N HIS K 255 86.261 37.679 48.986 1.00110.26 N +ATOM 20943 CA HIS K 255 86.355 38.874 49.825 1.00138.79 C +ATOM 20944 C HIS K 255 84.982 39.383 50.240 1.00130.22 C +ATOM 20945 O HIS K 255 84.825 39.933 51.329 1.00162.61 O +ATOM 20946 CB HIS K 255 87.164 39.985 49.117 1.00156.10 C +ATOM 20947 CG HIS K 255 88.533 40.188 49.686 1.00155.79 C +ATOM 20948 ND1 HIS K 255 89.568 39.298 49.478 1.00141.80 N +ATOM 20949 CD2 HIS K 255 89.029 41.165 50.482 1.00168.23 C +ATOM 20950 CE1 HIS K 255 90.646 39.729 50.109 1.00165.49 C +ATOM 20951 NE2 HIS K 255 90.345 40.859 50.727 1.00184.99 N +ATOM 20952 N MET K 256 83.999 39.249 49.355 1.00121.34 N +ATOM 20953 CA MET K 256 82.654 39.732 49.669 1.00128.45 C +ATOM 20954 C MET K 256 82.014 38.886 50.784 1.00144.23 C +ATOM 20955 O MET K 256 81.136 39.367 51.504 1.00121.91 O +ATOM 20956 CB MET K 256 81.786 39.762 48.405 1.00123.70 C +ATOM 20957 CG MET K 256 82.398 40.555 47.248 1.00115.53 C +ATOM 20958 SD MET K 256 81.254 41.086 45.952 1.00107.11 S +ATOM 20959 CE MET K 256 80.282 42.309 46.859 1.00 89.49 C +ATOM 20960 N SER K 257 82.506 37.654 50.955 1.00161.74 N +ATOM 20961 CA SER K 257 82.073 36.758 52.043 1.00147.09 C +ATOM 20962 C SER K 257 82.704 37.145 53.382 1.00123.32 C +ATOM 20963 O SER K 257 82.129 37.937 54.122 1.00 99.18 O +ATOM 20964 CB SER K 257 82.428 35.296 51.718 1.00134.96 C +ATOM 20965 OG SER K 257 82.136 34.976 50.368 1.00118.05 O +TER 20966 SER K 257 +ATOM 20967 N LEU L 2 70.889 56.148 21.773 1.00129.91 N +ATOM 20968 CA LEU L 2 70.405 56.218 23.183 1.00110.92 C +ATOM 20969 C LEU L 2 68.868 56.061 23.214 1.00108.19 C +ATOM 20970 O LEU L 2 68.109 57.004 23.539 1.00 67.44 O +ATOM 20971 CB LEU L 2 70.853 57.519 23.861 1.00118.04 C +ATOM 20972 CG LEU L 2 72.371 57.787 24.013 1.00137.42 C +ATOM 20973 CD1 LEU L 2 72.577 59.145 24.688 1.00149.76 C +ATOM 20974 CD2 LEU L 2 73.153 56.702 24.768 1.00121.88 C +ATOM 20975 N THR L 3 68.452 54.863 22.787 1.00111.42 N +ATOM 20976 CA THR L 3 67.131 54.284 23.048 1.00120.33 C +ATOM 20977 C THR L 3 67.221 52.738 23.290 1.00159.02 C +ATOM 20978 O THR L 3 66.209 52.077 23.576 1.00156.27 O +ATOM 20979 CB THR L 3 66.168 54.494 21.873 1.00 91.13 C +ATOM 20980 OG1 THR L 3 66.609 53.693 20.753 1.00151.45 O +ATOM 20981 CG2 THR L 3 66.069 55.960 21.502 1.00 79.06 C +ATOM 20982 N ALA L 4 68.415 52.164 23.142 1.00162.15 N +ATOM 20983 CA ALA L 4 68.696 50.808 23.643 1.00144.07 C +ATOM 20984 C ALA L 4 68.839 50.835 25.187 1.00148.08 C +ATOM 20985 O ALA L 4 68.628 51.877 25.814 1.00149.09 O +ATOM 20986 CB ALA L 4 69.950 50.246 22.982 1.00140.90 C +ATOM 20987 N PRO L 5 69.170 49.696 25.826 1.00136.21 N +ATOM 20988 CA PRO L 5 68.886 49.766 27.264 1.00137.82 C +ATOM 20989 C PRO L 5 69.997 50.434 28.040 1.00142.41 C +ATOM 20990 O PRO L 5 71.077 50.677 27.483 1.00167.15 O +ATOM 20991 CB PRO L 5 68.766 48.299 27.668 1.00142.37 C +ATOM 20992 CG PRO L 5 69.586 47.538 26.657 1.00136.03 C +ATOM 20993 CD PRO L 5 69.745 48.396 25.428 1.00110.51 C +ATOM 20994 N PRO L 6 69.736 50.752 29.314 1.00142.41 N +ATOM 20995 CA PRO L 6 70.823 51.111 30.241 1.00158.70 C +ATOM 20996 C PRO L 6 71.567 49.913 30.864 1.00145.90 C +ATOM 20997 O PRO L 6 71.014 48.825 30.966 1.00102.71 O +ATOM 20998 CB PRO L 6 70.115 51.893 31.341 1.00135.32 C +ATOM 20999 CG PRO L 6 68.673 51.541 31.235 1.00127.89 C +ATOM 21000 CD PRO L 6 68.397 50.954 29.885 1.00111.45 C +ATOM 21001 N LYS L 7 72.836 50.115 31.215 1.00144.26 N +ATOM 21002 CA LYS L 7 73.642 49.093 31.911 1.00141.62 C +ATOM 21003 C LYS L 7 73.710 49.410 33.395 1.00131.76 C +ATOM 21004 O LYS L 7 73.224 50.449 33.842 1.00 79.08 O +ATOM 21005 CB LYS L 7 75.069 48.994 31.348 1.00133.75 C +ATOM 21006 CG LYS L 7 75.170 48.362 29.975 1.00125.30 C +ATOM 21007 CD LYS L 7 75.378 49.375 28.849 1.00112.39 C +ATOM 21008 CE LYS L 7 75.757 48.664 27.559 1.00 97.00 C +ATOM 21009 NZ LYS L 7 75.304 49.420 26.361 1.00 98.76 N +ATOM 21010 N GLU L 8 74.248 48.463 34.162 1.00143.65 N +ATOM 21011 CA GLU L 8 74.000 48.393 35.606 1.00136.35 C +ATOM 21012 C GLU L 8 74.589 49.522 36.392 1.00109.58 C +ATOM 21013 O GLU L 8 75.789 49.694 36.421 1.00101.07 O +ATOM 21014 CB GLU L 8 74.488 47.089 36.201 1.00136.77 C +ATOM 21015 CG GLU L 8 73.292 46.382 36.857 1.00152.37 C +ATOM 21016 CD GLU L 8 72.806 45.136 36.113 1.00166.74 C +ATOM 21017 OE1 GLU L 8 72.783 45.178 34.854 1.00244.70 O +ATOM 21018 OE2 GLU L 8 72.379 44.144 36.773 1.00128.34 O +ATOM 21019 N ALA L 9 73.708 50.276 37.034 1.00118.68 N +ATOM 21020 CA ALA L 9 74.082 51.273 38.005 1.00120.21 C +ATOM 21021 C ALA L 9 73.963 50.660 39.411 1.00 97.00 C +ATOM 21022 O ALA L 9 72.861 50.423 39.909 1.00 71.52 O +ATOM 21023 CB ALA L 9 73.183 52.496 37.855 1.00119.52 C +ATOM 21024 N ALA L 10 75.118 50.479 40.051 1.00 84.63 N +ATOM 21025 CA ALA L 10 75.270 49.781 41.333 1.00 72.47 C +ATOM 21026 C ALA L 10 75.412 48.317 41.075 1.00 64.53 C +ATOM 21027 O ALA L 10 74.968 47.806 40.035 1.00 78.27 O +ATOM 21028 CB ALA L 10 74.133 50.082 42.318 1.00 74.18 C +ATOM 21029 N ARG L 11 76.048 47.636 42.012 1.00 63.35 N +ATOM 21030 CA ARG L 11 76.482 46.256 41.790 1.00 99.36 C +ATOM 21031 C ARG L 11 75.595 45.248 42.552 1.00 97.31 C +ATOM 21032 O ARG L 11 75.090 45.564 43.629 1.00115.51 O +ATOM 21033 CB ARG L 11 77.913 46.117 42.304 1.00140.26 C +ATOM 21034 CG ARG L 11 77.883 46.234 43.835 1.00164.87 C +ATOM 21035 CD ARG L 11 78.823 47.237 44.416 1.00161.26 C +ATOM 21036 NE ARG L 11 78.083 47.979 45.449 1.00144.41 N +ATOM 21037 CZ ARG L 11 77.201 48.984 45.289 1.00111.73 C +ATOM 21038 NH1 ARG L 11 76.988 49.585 44.119 1.00 84.80 N +ATOM 21039 NH2 ARG L 11 76.569 49.448 46.366 1.00109.27 N +ATOM 21040 N PRO L 12 75.502 43.996 42.065 1.00 89.20 N +ATOM 21041 CA PRO L 12 74.973 42.950 42.921 1.00 89.53 C +ATOM 21042 C PRO L 12 75.897 42.666 44.108 1.00116.30 C +ATOM 21043 O PRO L 12 77.050 42.249 43.932 1.00111.52 O +ATOM 21044 CB PRO L 12 74.910 41.731 42.003 1.00 91.34 C +ATOM 21045 CG PRO L 12 75.138 42.240 40.629 1.00107.17 C +ATOM 21046 CD PRO L 12 75.974 43.463 40.782 1.00100.76 C +ATOM 21047 N THR L 13 75.410 42.972 45.308 1.00118.37 N +ATOM 21048 CA THR L 13 76.045 42.522 46.542 1.00109.64 C +ATOM 21049 C THR L 13 75.334 41.275 47.091 1.00 90.33 C +ATOM 21050 O THR L 13 74.204 41.008 46.714 1.00 69.95 O +ATOM 21051 CB THR L 13 75.973 43.622 47.599 1.00111.60 C +ATOM 21052 OG1 THR L 13 76.803 43.253 48.709 1.00152.61 O +ATOM 21053 CG2 THR L 13 74.502 43.893 48.052 1.00 88.20 C +ATOM 21054 N LEU L 14 75.970 40.518 47.982 1.00 84.34 N +ATOM 21055 CA LEU L 14 75.211 39.471 48.697 1.00 79.23 C +ATOM 21056 C LEU L 14 74.396 40.152 49.806 1.00 66.02 C +ATOM 21057 O LEU L 14 74.613 41.312 50.074 1.00 56.30 O +ATOM 21058 CB LEU L 14 76.080 38.319 49.205 1.00 74.96 C +ATOM 21059 CG LEU L 14 77.284 38.662 50.042 1.00 86.53 C +ATOM 21060 CD1 LEU L 14 77.527 37.575 51.072 1.00 97.95 C +ATOM 21061 CD2 LEU L 14 78.493 38.795 49.152 1.00 89.96 C +ATOM 21062 N MET L 15 73.331 39.521 50.284 1.00 73.67 N +ATOM 21063 CA MET L 15 72.172 40.277 50.806 1.00 84.33 C +ATOM 21064 C MET L 15 72.531 40.944 52.135 1.00 92.04 C +ATOM 21065 O MET L 15 72.980 40.269 53.064 1.00125.29 O +ATOM 21066 CB MET L 15 70.935 39.381 50.973 1.00 90.88 C +ATOM 21067 CG MET L 15 69.635 40.161 50.857 1.00102.30 C +ATOM 21068 SD MET L 15 68.236 39.793 51.914 1.00140.95 S +ATOM 21069 CE MET L 15 68.855 38.741 53.225 1.00124.03 C +ATOM 21070 N PRO L 16 72.355 42.277 52.220 1.00 81.05 N +ATOM 21071 CA PRO L 16 72.805 43.085 53.339 1.00 88.92 C +ATOM 21072 C PRO L 16 72.104 42.739 54.667 1.00 98.29 C +ATOM 21073 O PRO L 16 71.226 43.475 55.115 1.00109.70 O +ATOM 21074 CB PRO L 16 72.470 44.518 52.887 1.00 79.72 C +ATOM 21075 CG PRO L 16 71.376 44.361 51.914 1.00 66.61 C +ATOM 21076 CD PRO L 16 71.701 43.098 51.193 1.00 72.38 C +ATOM 21077 N ARG L 17 72.625 41.724 55.354 1.00 84.89 N +ATOM 21078 CA ARG L 17 72.230 41.420 56.730 1.00 81.78 C +ATOM 21079 C ARG L 17 73.100 42.150 57.754 1.00 74.92 C +ATOM 21080 O ARG L 17 74.244 42.456 57.469 1.00 58.40 O +ATOM 21081 CB ARG L 17 72.347 39.935 56.970 1.00 79.28 C +ATOM 21082 CG ARG L 17 71.114 39.145 56.530 1.00 84.46 C +ATOM 21083 CD ARG L 17 71.371 37.649 56.380 1.00 71.56 C +ATOM 21084 NE ARG L 17 71.993 37.343 55.098 1.00 93.07 N +ATOM 21085 CZ ARG L 17 72.548 36.176 54.801 1.00112.94 C +ATOM 21086 NH1 ARG L 17 72.459 35.188 55.675 1.00102.62 N +ATOM 21087 NH2 ARG L 17 73.180 35.989 53.628 1.00131.55 N +ATOM 21088 N ALA L 18 72.494 42.590 58.859 1.00 87.47 N +ATOM 21089 CA ALA L 18 73.191 43.455 59.822 1.00105.89 C +ATOM 21090 C ALA L 18 73.444 42.757 61.159 1.00121.66 C +ATOM 21091 O ALA L 18 74.146 41.741 61.193 1.00169.48 O +ATOM 21092 CB ALA L 18 72.463 44.782 60.034 1.00109.77 C +ATOM 21093 N GLN L 19 72.904 43.301 62.254 1.00 98.35 N +ATOM 21094 CA GLN L 19 73.396 42.962 63.594 1.00 88.36 C +ATOM 21095 C GLN L 19 73.050 41.526 64.000 1.00 78.85 C +ATOM 21096 O GLN L 19 73.907 40.755 64.458 1.00 63.28 O +ATOM 21097 CB GLN L 19 72.832 43.941 64.625 1.00 93.58 C +ATOM 21098 CG GLN L 19 73.405 43.776 66.030 1.00119.52 C +ATOM 21099 CD GLN L 19 74.926 43.850 66.072 1.00127.11 C +ATOM 21100 OE1 GLN L 19 75.515 44.892 65.783 1.00112.38 O +ATOM 21101 NE2 GLN L 19 75.567 42.724 66.390 1.00122.67 N +ATOM 21102 N SER L 20 71.773 41.193 63.837 1.00 95.02 N +ATOM 21103 CA SER L 20 71.250 39.834 64.029 1.00 90.27 C +ATOM 21104 C SER L 20 72.159 38.768 63.398 1.00 77.58 C +ATOM 21105 O SER L 20 72.603 37.841 64.078 1.00 69.26 O +ATOM 21106 CB SER L 20 69.840 39.742 63.424 1.00 72.80 C +ATOM 21107 OG SER L 20 69.028 40.805 63.906 1.00 58.46 O +ATOM 21108 N TYR L 21 72.511 38.988 62.137 1.00 70.20 N +ATOM 21109 CA TYR L 21 73.474 38.151 61.445 1.00 75.66 C +ATOM 21110 C TYR L 21 74.815 38.012 62.187 1.00 75.91 C +ATOM 21111 O TYR L 21 75.344 36.895 62.342 1.00 54.83 O +ATOM 21112 CB TYR L 21 73.722 38.696 60.033 1.00 86.54 C +ATOM 21113 CG TYR L 21 74.645 37.823 59.210 1.00106.59 C +ATOM 21114 CD1 TYR L 21 74.188 36.633 58.649 1.00118.08 C +ATOM 21115 CD2 TYR L 21 75.972 38.175 58.996 1.00113.52 C +ATOM 21116 CE1 TYR L 21 75.023 35.825 57.903 1.00124.61 C +ATOM 21117 CE2 TYR L 21 76.811 37.369 58.239 1.00121.37 C +ATOM 21118 CZ TYR L 21 76.323 36.197 57.695 1.00121.42 C +ATOM 21119 OH TYR L 21 77.113 35.390 56.909 1.00186.31 O +ATOM 21120 N LYS L 22 75.407 39.153 62.566 1.00 88.39 N +ATOM 21121 CA LYS L 22 76.743 39.183 63.183 1.00 82.73 C +ATOM 21122 C LYS L 22 76.766 38.420 64.487 1.00 78.79 C +ATOM 21123 O LYS L 22 77.709 37.671 64.767 1.00 75.88 O +ATOM 21124 CB LYS L 22 77.183 40.614 63.431 1.00 87.68 C +ATOM 21125 CG LYS L 22 77.937 41.228 62.269 1.00123.57 C +ATOM 21126 CD LYS L 22 79.416 40.799 62.297 1.00152.63 C +ATOM 21127 CE LYS L 22 80.286 41.933 62.859 1.00175.31 C +ATOM 21128 NZ LYS L 22 80.279 43.124 61.965 1.00184.79 N +ATOM 21129 N ASP L 23 75.687 38.565 65.248 1.00 87.79 N +ATOM 21130 CA ASP L 23 75.481 37.762 66.453 1.00 96.36 C +ATOM 21131 C ASP L 23 75.336 36.274 66.129 1.00107.18 C +ATOM 21132 O ASP L 23 75.953 35.418 66.782 1.00136.86 O +ATOM 21133 CB ASP L 23 74.238 38.240 67.207 1.00 73.41 C +ATOM 21134 CG ASP L 23 74.404 39.624 67.743 1.00 72.68 C +ATOM 21135 OD1 ASP L 23 75.496 39.902 68.289 1.00 83.00 O +ATOM 21136 OD2 ASP L 23 73.433 40.404 67.696 1.00 69.88 O +ATOM 21137 N LEU L 24 74.513 35.983 65.125 1.00 95.39 N +ATOM 21138 CA LEU L 24 74.163 34.611 64.764 1.00102.48 C +ATOM 21139 C LEU L 24 75.379 33.807 64.269 1.00105.87 C +ATOM 21140 O LEU L 24 75.492 32.592 64.539 1.00 81.18 O +ATOM 21141 CB LEU L 24 73.080 34.630 63.689 1.00 92.75 C +ATOM 21142 CG LEU L 24 72.562 33.278 63.178 1.00 89.38 C +ATOM 21143 CD1 LEU L 24 71.439 32.759 64.049 1.00 82.91 C +ATOM 21144 CD2 LEU L 24 72.090 33.421 61.738 1.00107.27 C +ATOM 21145 N THR L 25 76.292 34.493 63.578 1.00108.11 N +ATOM 21146 CA THR L 25 77.469 33.839 63.002 1.00126.23 C +ATOM 21147 C THR L 25 78.534 33.553 64.047 1.00137.36 C +ATOM 21148 O THR L 25 79.059 32.426 64.117 1.00135.43 O +ATOM 21149 CB THR L 25 78.099 34.691 61.885 1.00123.25 C +ATOM 21150 OG1 THR L 25 78.199 36.052 62.310 1.00 92.25 O +ATOM 21151 CG2 THR L 25 77.244 34.612 60.624 1.00131.22 C +ATOM 21152 N HIS L 26 78.817 34.558 64.879 1.00132.14 N +ATOM 21153 CA HIS L 26 79.834 34.453 65.925 1.00129.31 C +ATOM 21154 C HIS L 26 79.272 33.798 67.206 1.00119.63 C +ATOM 21155 O HIS L 26 79.667 34.138 68.306 1.00108.24 O +ATOM 21156 CB HIS L 26 80.425 35.840 66.231 1.00115.27 C +ATOM 21157 CG HIS L 26 81.149 36.449 65.071 1.00130.95 C +ATOM 21158 ND1 HIS L 26 80.493 36.888 63.942 1.00163.78 N +ATOM 21159 CD2 HIS L 26 82.471 36.623 64.828 1.00127.73 C +ATOM 21160 CE1 HIS L 26 81.376 37.339 63.068 1.00175.17 C +ATOM 21161 NE2 HIS L 26 82.585 37.178 63.577 1.00154.71 N +ATOM 21162 N LEU L 27 78.396 32.810 67.048 1.00125.32 N +ATOM 21163 CA LEU L 27 77.920 32.019 68.178 1.00105.05 C +ATOM 21164 C LEU L 27 78.851 30.842 68.417 1.00102.00 C +ATOM 21165 O LEU L 27 79.240 30.146 67.472 1.00127.88 O +ATOM 21166 CB LEU L 27 76.501 31.501 67.927 1.00102.45 C +ATOM 21167 CG LEU L 27 75.383 32.462 68.337 1.00105.36 C +ATOM 21168 CD1 LEU L 27 74.046 32.016 67.765 1.00 88.94 C +ATOM 21169 CD2 LEU L 27 75.295 32.590 69.847 1.00116.35 C +ATOM 21170 N PRO L 28 79.239 30.628 69.681 1.00 85.12 N +ATOM 21171 CA PRO L 28 80.102 29.504 70.032 1.00 77.04 C +ATOM 21172 C PRO L 28 79.525 28.165 69.614 1.00 80.78 C +ATOM 21173 O PRO L 28 78.377 27.861 69.908 1.00115.13 O +ATOM 21174 CB PRO L 28 80.176 29.582 71.546 1.00 80.79 C +ATOM 21175 CG PRO L 28 78.933 30.297 71.963 1.00 84.94 C +ATOM 21176 CD PRO L 28 78.664 31.280 70.869 1.00 87.88 C +ATOM 21177 N ALA L 29 80.320 27.349 68.947 1.00 83.97 N +ATOM 21178 CA ALA L 29 79.780 26.166 68.270 1.00 90.08 C +ATOM 21179 C ALA L 29 79.389 25.059 69.272 1.00 63.21 C +ATOM 21180 O ALA L 29 80.034 24.890 70.301 1.00 56.56 O +ATOM 21181 CB ALA L 29 80.783 25.658 67.204 1.00123.92 C +ATOM 21182 N PRO L 30 78.344 24.301 68.959 1.00 54.93 N +ATOM 21183 CA PRO L 30 78.008 23.097 69.710 1.00 69.09 C +ATOM 21184 C PRO L 30 78.985 21.917 69.545 1.00 62.63 C +ATOM 21185 O PRO L 30 79.817 21.935 68.640 1.00 67.36 O +ATOM 21186 CB PRO L 30 76.633 22.725 69.128 1.00 83.84 C +ATOM 21187 CG PRO L 30 76.691 23.175 67.705 1.00 75.57 C +ATOM 21188 CD PRO L 30 77.603 24.379 67.686 1.00 64.97 C +ATOM 21189 N THR L 31 78.740 20.829 70.273 1.00 68.63 N +ATOM 21190 CA THR L 31 79.556 19.617 70.144 1.00 86.66 C +ATOM 21191 C THR L 31 79.412 18.918 68.784 1.00 96.67 C +ATOM 21192 O THR L 31 80.322 18.199 68.339 1.00114.60 O +ATOM 21193 CB THR L 31 79.291 18.588 71.278 1.00105.00 C +ATOM 21194 OG1 THR L 31 77.893 18.261 71.362 1.00141.62 O +ATOM 21195 CG2 THR L 31 79.760 19.135 72.614 1.00105.15 C +ATOM 21196 N GLY L 32 78.253 19.070 68.156 1.00101.29 N +ATOM 21197 CA GLY L 32 78.063 18.629 66.771 1.00115.86 C +ATOM 21198 C GLY L 32 76.899 19.392 66.188 1.00114.56 C +ATOM 21199 O GLY L 32 76.043 19.866 66.940 1.00118.23 O +ATOM 21200 N LYS L 33 76.868 19.557 64.868 1.00101.67 N +ATOM 21201 CA LYS L 33 75.741 20.258 64.252 1.00 99.60 C +ATOM 21202 C LYS L 33 74.466 19.408 64.348 1.00102.03 C +ATOM 21203 O LYS L 33 74.553 18.180 64.410 1.00 97.37 O +ATOM 21204 CB LYS L 33 76.029 20.624 62.801 1.00 88.62 C +ATOM 21205 CG LYS L 33 76.665 21.987 62.622 1.00 88.79 C +ATOM 21206 CD LYS L 33 77.083 22.195 61.177 1.00114.54 C +ATOM 21207 CE LYS L 33 78.234 23.187 61.083 1.00121.01 C +ATOM 21208 NZ LYS L 33 78.771 23.281 59.704 1.00136.68 N +ATOM 21209 N ILE L 34 73.304 20.064 64.412 1.00 88.01 N +ATOM 21210 CA ILE L 34 72.054 19.362 64.584 1.00 76.68 C +ATOM 21211 C ILE L 34 71.320 19.385 63.242 1.00 82.38 C +ATOM 21212 O ILE L 34 71.418 20.334 62.472 1.00 62.96 O +ATOM 21213 CB ILE L 34 71.242 19.958 65.765 1.00 99.63 C +ATOM 21214 CG1 ILE L 34 71.963 19.712 67.096 1.00104.04 C +ATOM 21215 CG2 ILE L 34 69.851 19.338 65.888 1.00124.94 C +ATOM 21216 CD1 ILE L 34 72.371 20.985 67.808 1.00104.97 C +ATOM 21217 N PHE L 35 70.654 18.271 62.936 1.00115.97 N +ATOM 21218 CA PHE L 35 69.869 18.095 61.699 1.00 99.50 C +ATOM 21219 C PHE L 35 68.485 18.711 61.848 1.00 59.30 C +ATOM 21220 O PHE L 35 67.741 18.291 62.733 1.00 72.22 O +ATOM 21221 CB PHE L 35 69.692 16.586 61.424 1.00107.21 C +ATOM 21222 CG PHE L 35 70.827 15.945 60.662 1.00 98.25 C +ATOM 21223 CD1 PHE L 35 71.385 16.559 59.556 1.00 79.51 C +ATOM 21224 CD2 PHE L 35 71.255 14.665 61.003 1.00 99.28 C +ATOM 21225 CE1 PHE L 35 72.421 15.961 58.883 1.00 79.97 C +ATOM 21226 CE2 PHE L 35 72.287 14.053 60.313 1.00 83.30 C +ATOM 21227 CZ PHE L 35 72.860 14.698 59.243 1.00 81.02 C +ATOM 21228 N VAL L 36 68.154 19.651 60.993 1.00 36.64 N +ATOM 21229 CA VAL L 36 66.885 20.280 61.098 1.00 41.15 C +ATOM 21230 C VAL L 36 66.054 20.308 59.790 1.00 55.27 C +ATOM 21231 O VAL L 36 66.601 20.251 58.691 1.00 91.17 O +ATOM 21232 CB VAL L 36 67.093 21.685 61.548 1.00 38.40 C +ATOM 21233 CG1 VAL L 36 67.601 22.546 60.410 1.00 43.60 C +ATOM 21234 CG2 VAL L 36 65.789 22.256 62.066 1.00 41.56 C +ATOM 21235 N SER L 37 64.719 20.325 59.912 1.00 57.12 N +ATOM 21236 CA SER L 37 63.777 20.313 58.753 1.00 46.87 C +ATOM 21237 C SER L 37 62.856 21.503 58.795 1.00 45.58 C +ATOM 21238 O SER L 37 62.367 21.839 59.862 1.00 70.08 O +ATOM 21239 CB SER L 37 62.878 19.093 58.793 1.00 29.72 C +ATOM 21240 OG SER L 37 63.604 17.946 58.424 1.00 29.08 O +ATOM 21241 N VAL L 38 62.778 22.253 57.714 1.00 40.93 N +ATOM 21242 CA VAL L 38 61.808 23.323 57.675 1.00 48.23 C +ATOM 21243 C VAL L 38 60.913 23.078 56.488 1.00 72.75 C +ATOM 21244 O VAL L 38 61.399 23.065 55.339 1.00136.34 O +ATOM 21245 CB VAL L 38 62.428 24.730 57.500 1.00 56.88 C +ATOM 21246 CG1 VAL L 38 61.310 25.762 57.363 1.00 62.56 C +ATOM 21247 CG2 VAL L 38 63.361 25.116 58.648 1.00 51.55 C +ATOM 21248 N TYR L 39 59.619 22.872 56.747 1.00 68.82 N +ATOM 21249 CA TYR L 39 58.634 22.529 55.694 1.00 45.49 C +ATOM 21250 C TYR L 39 58.002 23.824 55.177 1.00 60.13 C +ATOM 21251 O TYR L 39 58.052 24.115 53.978 1.00110.86 O +ATOM 21252 CB TYR L 39 57.594 21.571 56.226 1.00 35.27 C +ATOM 21253 CG TYR L 39 58.002 20.158 56.136 1.00 33.56 C +ATOM 21254 CD1 TYR L 39 58.856 19.595 57.049 1.00 39.23 C +ATOM 21255 CD2 TYR L 39 57.484 19.339 55.156 1.00 53.53 C +ATOM 21256 CE1 TYR L 39 59.256 18.267 56.938 1.00 57.86 C +ATOM 21257 CE2 TYR L 39 57.856 17.991 55.027 1.00 62.00 C +ATOM 21258 CZ TYR L 39 58.728 17.445 55.917 1.00 56.89 C +ATOM 21259 OH TYR L 39 59.094 16.114 55.800 1.00 31.64 O +ATOM 21260 N ASN L 40 57.557 24.693 56.076 1.00 63.76 N +ATOM 21261 CA ASN L 40 56.935 25.938 55.653 1.00 68.06 C +ATOM 21262 C ASN L 40 56.684 26.927 56.790 1.00 66.16 C +ATOM 21263 O ASN L 40 56.114 26.573 57.823 1.00 62.68 O +ATOM 21264 CB ASN L 40 55.606 25.640 54.949 1.00 70.42 C +ATOM 21265 CG ASN L 40 55.142 26.792 54.082 1.00 93.70 C +ATOM 21266 OD1 ASN L 40 55.838 27.246 53.151 1.00110.83 O +ATOM 21267 ND2 ASN L 40 53.949 27.265 54.371 1.00105.97 N +ATOM 21268 N ILE L 41 57.054 28.183 56.567 1.00 69.83 N +ATOM 21269 CA ILE L 41 56.627 29.274 57.432 1.00 81.09 C +ATOM 21270 C ILE L 41 55.724 30.236 56.637 1.00 90.63 C +ATOM 21271 O ILE L 41 56.185 30.890 55.694 1.00113.59 O +ATOM 21272 CB ILE L 41 57.838 30.045 58.036 1.00 75.71 C +ATOM 21273 CG1 ILE L 41 58.450 29.285 59.220 1.00 62.44 C +ATOM 21274 CG2 ILE L 41 57.402 31.413 58.569 1.00 61.36 C +ATOM 21275 CD1 ILE L 41 59.174 28.015 58.848 1.00 62.88 C +ATOM 21276 N GLN L 42 54.456 30.356 57.043 1.00 79.53 N +ATOM 21277 CA GLN L 42 53.461 31.092 56.252 1.00 75.37 C +ATOM 21278 C GLN L 42 53.442 32.592 56.553 1.00 67.73 C +ATOM 21279 O GLN L 42 53.766 33.008 57.664 1.00 58.52 O +ATOM 21280 CB GLN L 42 52.060 30.507 56.459 1.00 81.17 C +ATOM 21281 CG GLN L 42 51.893 29.100 55.918 1.00 97.47 C +ATOM 21282 CD GLN L 42 51.387 28.050 56.893 1.00115.83 C +ATOM 21283 OE1 GLN L 42 52.107 27.098 57.183 1.00 92.51 O +ATOM 21284 NE2 GLN L 42 50.085 28.095 57.222 1.00120.41 N +ATOM 21285 N ASP L 43 52.986 33.377 55.570 1.00 63.35 N +ATOM 21286 CA ASP L 43 52.560 34.746 55.789 1.00 58.30 C +ATOM 21287 C ASP L 43 51.159 34.801 56.443 1.00 64.45 C +ATOM 21288 O ASP L 43 50.224 35.339 55.875 1.00 53.22 O +ATOM 21289 CB ASP L 43 52.513 35.493 54.477 1.00 59.11 C +ATOM 21290 CG ASP L 43 52.354 37.009 54.672 1.00 84.37 C +ATOM 21291 OD1 ASP L 43 53.138 37.606 55.446 1.00106.59 O +ATOM 21292 OD2 ASP L 43 51.513 37.651 53.991 1.00109.57 O +ATOM 21293 N GLU L 44 51.054 34.331 57.695 1.00 78.87 N +ATOM 21294 CA GLU L 44 49.770 34.318 58.450 1.00 59.56 C +ATOM 21295 C GLU L 44 49.246 35.733 58.786 1.00 55.74 C +ATOM 21296 O GLU L 44 48.438 35.904 59.691 1.00 68.56 O +ATOM 21297 CB GLU L 44 49.932 33.433 59.721 1.00 68.82 C +ATOM 21298 CG GLU L 44 49.658 31.945 59.515 1.00 65.73 C +ATOM 21299 CD GLU L 44 49.858 31.071 60.782 1.00 75.59 C +ATOM 21300 OE1 GLU L 44 49.396 31.436 61.905 1.00 80.09 O +ATOM 21301 OE2 GLU L 44 50.427 29.956 60.660 1.00 74.60 O +ATOM 21302 N THR L 45 49.876 36.754 58.199 1.00 56.66 N +ATOM 21303 CA THR L 45 49.731 38.146 58.649 1.00 74.68 C +ATOM 21304 C THR L 45 48.356 38.682 58.260 1.00 77.05 C +ATOM 21305 O THR L 45 47.766 39.450 59.012 1.00 69.49 O +ATOM 21306 CB THR L 45 50.906 39.092 58.166 1.00 88.49 C +ATOM 21307 OG1 THR L 45 50.832 40.355 58.831 1.00 90.66 O +ATOM 21308 CG2 THR L 45 50.862 39.351 56.670 1.00104.39 C +ATOM 21309 N GLY L 46 47.919 38.391 57.041 1.00 83.55 N +ATOM 21310 CA GLY L 46 46.574 38.784 56.591 1.00 87.87 C +ATOM 21311 C GLY L 46 46.513 40.155 55.935 1.00 80.96 C +ATOM 21312 O GLY L 46 45.467 40.811 55.819 1.00 49.41 O +ATOM 21313 N GLN L 47 47.659 40.619 55.489 1.00 88.92 N +ATOM 21314 CA GLN L 47 47.765 42.007 55.237 1.00 80.72 C +ATOM 21315 C GLN L 47 48.360 42.302 53.874 1.00 72.91 C +ATOM 21316 O GLN L 47 49.304 41.648 53.413 1.00 55.01 O +ATOM 21317 CB GLN L 47 48.575 42.634 56.330 1.00 69.25 C +ATOM 21318 CG GLN L 47 47.844 42.633 57.637 1.00 76.21 C +ATOM 21319 CD GLN L 47 46.422 43.166 57.500 1.00 87.41 C +ATOM 21320 OE1 GLN L 47 46.217 44.371 57.399 1.00 83.04 O +ATOM 21321 NE2 GLN L 47 45.441 42.287 57.650 1.00 78.20 N +ATOM 21322 N PHE L 48 47.760 43.301 53.236 1.00 58.92 N +ATOM 21323 CA PHE L 48 48.196 43.770 51.946 1.00 53.26 C +ATOM 21324 C PHE L 48 48.487 45.261 52.005 1.00 65.97 C +ATOM 21325 O PHE L 48 48.076 45.976 52.939 1.00 62.84 O +ATOM 21326 CB PHE L 48 47.113 43.500 50.909 1.00 53.24 C +ATOM 21327 CG PHE L 48 46.884 42.062 50.686 1.00 43.58 C +ATOM 21328 CD1 PHE L 48 46.178 41.307 51.617 1.00 34.54 C +ATOM 21329 CD2 PHE L 48 47.427 41.465 49.597 1.00 46.76 C +ATOM 21330 CE1 PHE L 48 46.004 39.973 51.470 1.00 34.38 C +ATOM 21331 CE2 PHE L 48 47.288 40.121 49.448 1.00 55.95 C +ATOM 21332 CZ PHE L 48 46.581 39.371 50.388 1.00 47.51 C +ATOM 21333 N LYS L 49 49.135 45.741 50.948 1.00 78.42 N +ATOM 21334 CA LYS L 49 49.529 47.141 50.853 1.00 80.78 C +ATOM 21335 C LYS L 49 48.330 48.000 50.481 1.00 79.47 C +ATOM 21336 O LYS L 49 47.436 47.540 49.760 1.00 96.22 O +ATOM 21337 CB LYS L 49 50.674 47.322 49.856 1.00 75.67 C +ATOM 21338 CG LYS L 49 51.954 46.626 50.303 1.00 86.66 C +ATOM 21339 CD LYS L 49 53.211 46.913 49.495 1.00 93.51 C +ATOM 21340 CE LYS L 49 54.391 46.269 50.235 1.00102.94 C +ATOM 21341 NZ LYS L 49 55.736 46.479 49.635 1.00 96.08 N +ATOM 21342 N PRO L 50 48.271 49.211 51.049 1.00 78.93 N +ATOM 21343 CA PRO L 50 47.188 50.133 50.808 1.00 85.84 C +ATOM 21344 C PRO L 50 47.389 50.871 49.501 1.00 85.64 C +ATOM 21345 O PRO L 50 48.461 50.756 48.849 1.00 74.58 O +ATOM 21346 CB PRO L 50 47.286 51.114 51.969 1.00 99.45 C +ATOM 21347 CG PRO L 50 48.723 51.100 52.352 1.00110.94 C +ATOM 21348 CD PRO L 50 49.211 49.713 52.070 1.00104.77 C +ATOM 21349 N TYR L 51 46.341 51.569 49.074 1.00 80.40 N +ATOM 21350 CA TYR L 51 46.446 52.383 47.880 1.00 83.29 C +ATOM 21351 C TYR L 51 47.678 53.275 48.033 1.00 91.59 C +ATOM 21352 O TYR L 51 47.897 53.826 49.108 1.00 66.10 O +ATOM 21353 CB TYR L 51 45.193 53.230 47.702 1.00 73.15 C +ATOM 21354 CG TYR L 51 45.137 53.852 46.337 1.00 90.11 C +ATOM 21355 CD1 TYR L 51 44.603 53.150 45.263 1.00 93.79 C +ATOM 21356 CD2 TYR L 51 45.644 55.127 46.098 1.00115.96 C +ATOM 21357 CE1 TYR L 51 44.576 53.677 43.987 1.00 94.85 C +ATOM 21358 CE2 TYR L 51 45.593 55.683 44.815 1.00132.74 C +ATOM 21359 CZ TYR L 51 45.085 54.926 43.761 1.00119.83 C +ATOM 21360 OH TYR L 51 45.005 55.419 42.475 1.00149.99 O +ATOM 21361 N PRO L 52 48.484 53.434 46.954 1.00102.08 N +ATOM 21362 CA PRO L 52 48.284 53.002 45.558 1.00104.29 C +ATOM 21363 C PRO L 52 48.905 51.679 45.134 1.00104.23 C +ATOM 21364 O PRO L 52 49.019 51.428 43.938 1.00126.19 O +ATOM 21365 CB PRO L 52 48.970 54.109 44.772 1.00120.95 C +ATOM 21366 CG PRO L 52 50.118 54.499 45.648 1.00128.44 C +ATOM 21367 CD PRO L 52 49.633 54.353 47.069 1.00111.21 C +ATOM 21368 N ALA L 53 49.220 50.808 46.082 1.00112.03 N +ATOM 21369 CA ALA L 53 49.707 49.476 45.725 1.00 94.11 C +ATOM 21370 C ALA L 53 48.642 48.662 45.006 1.00 77.02 C +ATOM 21371 O ALA L 53 47.428 48.960 45.076 1.00 55.25 O +ATOM 21372 CB ALA L 53 50.169 48.731 46.955 1.00 90.97 C +ATOM 21373 N SER L 54 49.097 47.632 44.302 1.00 74.89 N +ATOM 21374 CA SER L 54 48.157 46.654 43.783 1.00 83.04 C +ATOM 21375 C SER L 54 47.389 46.065 44.981 1.00 75.45 C +ATOM 21376 O SER L 54 47.934 45.818 46.040 1.00 46.90 O +ATOM 21377 CB SER L 54 48.843 45.543 42.947 1.00 66.60 C +ATOM 21378 OG SER L 54 48.049 44.363 42.875 1.00 44.15 O +ATOM 21379 N ASN L 55 46.113 45.810 44.752 1.00 66.15 N +ATOM 21380 CA ASN L 55 45.273 45.148 45.709 1.00 54.69 C +ATOM 21381 C ASN L 55 45.915 43.893 46.257 1.00 55.27 C +ATOM 21382 O ASN L 55 45.672 43.469 47.384 1.00 45.22 O +ATOM 21383 CB ASN L 55 43.959 44.793 45.021 1.00 55.81 C +ATOM 21384 CG ASN L 55 42.885 44.452 46.002 1.00 78.49 C +ATOM 21385 OD1 ASN L 55 42.936 44.805 47.183 1.00109.29 O +ATOM 21386 ND2 ASN L 55 41.858 43.838 45.501 1.00102.80 N +ATOM 21387 N PHE L 56 46.716 43.254 45.406 1.00 68.78 N +ATOM 21388 CA PHE L 56 47.251 41.907 45.676 1.00 64.59 C +ATOM 21389 C PHE L 56 48.647 41.942 46.265 1.00 77.38 C +ATOM 21390 O PHE L 56 49.270 40.899 46.439 1.00 73.40 O +ATOM 21391 CB PHE L 56 47.331 41.080 44.399 1.00 56.16 C +ATOM 21392 CG PHE L 56 46.030 40.873 43.759 1.00 56.35 C +ATOM 21393 CD1 PHE L 56 44.990 40.272 44.415 1.00 55.66 C +ATOM 21394 CD2 PHE L 56 45.816 41.401 42.522 1.00 91.96 C +ATOM 21395 CE1 PHE L 56 43.754 40.161 43.827 1.00 75.81 C +ATOM 21396 CE2 PHE L 56 44.590 41.255 41.897 1.00116.21 C +ATOM 21397 CZ PHE L 56 43.553 40.638 42.557 1.00103.07 C +ATOM 21398 N SER L 57 49.216 43.130 46.418 1.00 93.23 N +ATOM 21399 CA SER L 57 50.573 43.217 46.941 1.00 92.97 C +ATOM 21400 C SER L 57 50.523 42.945 48.444 1.00 84.87 C +ATOM 21401 O SER L 57 49.926 43.699 49.208 1.00 64.90 O +ATOM 21402 CB SER L 57 51.199 44.591 46.630 1.00108.58 C +ATOM 21403 OG SER L 57 51.568 44.670 45.262 1.00108.85 O +ATOM 21404 N THR L 58 51.135 41.848 48.849 1.00 83.20 N +ATOM 21405 CA THR L 58 51.179 41.502 50.243 1.00 79.58 C +ATOM 21406 C THR L 58 52.067 42.417 51.002 1.00 80.32 C +ATOM 21407 O THR L 58 53.032 42.996 50.499 1.00106.76 O +ATOM 21408 CB THR L 58 51.759 40.118 50.434 1.00 91.60 C +ATOM 21409 OG1 THR L 58 53.096 40.067 49.927 1.00 68.89 O +ATOM 21410 CG2 THR L 58 50.928 39.128 49.669 1.00117.45 C +ATOM 21411 N ALA L 59 51.769 42.567 52.257 1.00 92.27 N +ATOM 21412 CA ALA L 59 52.545 43.540 52.984 1.00 99.39 C +ATOM 21413 C ALA L 59 53.923 42.981 53.272 1.00 64.25 C +ATOM 21414 O ALA L 59 54.818 43.711 53.675 1.00 54.92 O +ATOM 21415 CB ALA L 59 51.805 43.972 54.239 1.00117.59 C +ATOM 21416 N VAL L 60 54.039 41.663 53.191 1.00 57.60 N +ATOM 21417 CA VAL L 60 55.192 40.950 53.739 1.00 61.15 C +ATOM 21418 C VAL L 60 55.590 39.879 52.744 1.00 41.91 C +ATOM 21419 O VAL L 60 54.735 39.272 52.131 1.00 35.01 O +ATOM 21420 CB VAL L 60 54.856 40.233 55.088 1.00 81.38 C +ATOM 21421 CG1 VAL L 60 56.058 39.463 55.617 1.00 76.96 C +ATOM 21422 CG2 VAL L 60 54.368 41.224 56.146 1.00 96.71 C +ATOM 21423 N PRO L 61 56.888 39.672 52.570 1.00 31.52 N +ATOM 21424 CA PRO L 61 57.296 38.776 51.507 1.00 28.15 C +ATOM 21425 C PRO L 61 56.987 37.393 51.901 1.00 26.82 C +ATOM 21426 O PRO L 61 57.042 37.052 53.090 1.00 19.07 O +ATOM 21427 CB PRO L 61 58.811 38.989 51.414 1.00 29.78 C +ATOM 21428 CG PRO L 61 59.191 39.681 52.705 1.00 35.06 C +ATOM 21429 CD PRO L 61 58.004 40.533 53.031 1.00 35.09 C +ATOM 21430 N GLN L 62 56.722 36.574 50.893 1.00 40.19 N +ATOM 21431 CA GLN L 62 56.269 35.211 51.118 1.00 52.85 C +ATOM 21432 C GLN L 62 57.444 34.295 51.137 1.00 41.61 C +ATOM 21433 O GLN L 62 57.337 33.165 50.736 1.00 48.84 O +ATOM 21434 CB GLN L 62 55.301 34.755 49.997 1.00 67.36 C +ATOM 21435 CG GLN L 62 54.141 35.712 49.697 1.00 70.73 C +ATOM 21436 CD GLN L 62 53.259 35.975 50.889 1.00 67.88 C +ATOM 21437 OE1 GLN L 62 52.451 35.127 51.290 1.00 87.23 O +ATOM 21438 NE2 GLN L 62 53.477 37.114 51.535 1.00 60.18 N +ATOM 21439 N SER L 63 58.516 34.739 51.735 1.00 54.82 N +ATOM 21440 CA SER L 63 59.808 34.091 51.559 1.00 81.35 C +ATOM 21441 C SER L 63 60.453 33.691 52.894 1.00113.25 C +ATOM 21442 O SER L 63 61.593 33.235 52.938 1.00 68.71 O +ATOM 21443 CB SER L 63 60.749 35.027 50.790 1.00 85.05 C +ATOM 21444 OG SER L 63 61.004 36.236 51.472 1.00 47.40 O +ATOM 21445 N ALA L 64 59.664 33.762 53.963 1.00153.29 N +ATOM 21446 CA ALA L 64 60.167 33.526 55.310 1.00144.02 C +ATOM 21447 C ALA L 64 60.874 32.156 55.449 1.00109.28 C +ATOM 21448 O ALA L 64 61.864 32.019 56.173 1.00 85.74 O +ATOM 21449 CB ALA L 64 59.017 33.671 56.310 1.00147.18 C +ATOM 21450 N THR L 65 60.290 31.132 54.832 1.00 80.54 N +ATOM 21451 CA THR L 65 60.769 29.764 54.959 1.00 64.27 C +ATOM 21452 C THR L 65 62.228 29.674 54.581 1.00 55.48 C +ATOM 21453 O THR L 65 63.028 29.085 55.307 1.00 82.29 O +ATOM 21454 CB THR L 65 59.994 28.870 54.003 1.00 82.86 C +ATOM 21455 OG1 THR L 65 58.613 29.261 53.995 1.00 83.49 O +ATOM 21456 CG2 THR L 65 60.142 27.389 54.370 1.00 67.27 C +ATOM 21457 N ALA L 66 62.575 30.265 53.453 1.00 52.70 N +ATOM 21458 CA ALA L 66 63.917 30.169 52.963 1.00 71.38 C +ATOM 21459 C ALA L 66 64.875 30.996 53.851 1.00 87.96 C +ATOM 21460 O ALA L 66 66.044 30.613 54.053 1.00 89.79 O +ATOM 21461 CB ALA L 66 63.972 30.630 51.520 1.00 84.64 C +ATOM 21462 N MET L 67 64.384 32.120 54.373 1.00 85.33 N +ATOM 21463 CA MET L 67 65.191 32.960 55.272 1.00 87.25 C +ATOM 21464 C MET L 67 65.546 32.182 56.545 1.00 68.75 C +ATOM 21465 O MET L 67 66.643 32.247 57.051 1.00 61.63 O +ATOM 21466 CB MET L 67 64.418 34.238 55.645 1.00107.46 C +ATOM 21467 CG MET L 67 64.246 35.268 54.536 1.00110.45 C +ATOM 21468 SD MET L 67 63.059 36.560 54.986 1.00 89.60 S +ATOM 21469 CE MET L 67 63.221 37.692 53.616 1.00126.37 C +ATOM 21470 N LEU L 68 64.569 31.463 57.075 1.00 58.37 N +ATOM 21471 CA LEU L 68 64.785 30.696 58.269 1.00 49.59 C +ATOM 21472 C LEU L 68 65.828 29.649 57.986 1.00 59.32 C +ATOM 21473 O LEU L 68 66.649 29.368 58.844 1.00 73.55 O +ATOM 21474 CB LEU L 68 63.472 30.036 58.760 1.00 60.30 C +ATOM 21475 CG LEU L 68 63.680 29.013 59.884 1.00 73.62 C +ATOM 21476 CD1 LEU L 68 64.199 29.688 61.145 1.00 85.30 C +ATOM 21477 CD2 LEU L 68 62.421 28.220 60.206 1.00 75.61 C +ATOM 21478 N VAL L 69 65.695 28.931 56.862 1.00 79.37 N +ATOM 21479 CA VAL L 69 66.606 27.804 56.553 1.00 76.23 C +ATOM 21480 C VAL L 69 68.012 28.358 56.428 1.00 56.45 C +ATOM 21481 O VAL L 69 68.960 27.802 56.995 1.00 44.16 O +ATOM 21482 CB VAL L 69 66.256 27.083 55.233 1.00 83.21 C +ATOM 21483 CG1 VAL L 69 67.365 26.111 54.870 1.00 87.64 C +ATOM 21484 CG2 VAL L 69 64.936 26.332 55.325 1.00 87.43 C +ATOM 21485 N THR L 70 68.108 29.513 55.787 1.00 45.62 N +ATOM 21486 CA THR L 70 69.377 30.180 55.657 1.00 67.81 C +ATOM 21487 C THR L 70 69.974 30.620 57.016 1.00 72.99 C +ATOM 21488 O THR L 70 71.164 30.404 57.295 1.00 86.33 O +ATOM 21489 CB THR L 70 69.235 31.397 54.751 1.00 87.88 C +ATOM 21490 OG1 THR L 70 68.687 30.970 53.505 1.00 98.18 O +ATOM 21491 CG2 THR L 70 70.611 32.054 54.505 1.00125.35 C +ATOM 21492 N ALA L 71 69.153 31.220 57.865 1.00 59.39 N +ATOM 21493 CA ALA L 71 69.611 31.596 59.203 1.00 48.65 C +ATOM 21494 C ALA L 71 70.070 30.359 60.015 1.00 44.05 C +ATOM 21495 O ALA L 71 71.047 30.400 60.726 1.00 39.34 O +ATOM 21496 CB ALA L 71 68.491 32.339 59.932 1.00 60.45 C +ATOM 21497 N LEU L 72 69.300 29.278 59.947 1.00 48.25 N +ATOM 21498 CA LEU L 72 69.652 28.041 60.627 1.00 51.24 C +ATOM 21499 C LEU L 72 70.993 27.515 60.143 1.00 64.65 C +ATOM 21500 O LEU L 72 71.671 26.801 60.863 1.00 58.84 O +ATOM 21501 CB LEU L 72 68.585 26.968 60.385 1.00 53.40 C +ATOM 21502 CG LEU L 72 67.242 27.258 61.041 1.00 50.14 C +ATOM 21503 CD1 LEU L 72 66.186 26.358 60.403 1.00 66.68 C +ATOM 21504 CD2 LEU L 72 67.288 27.015 62.526 1.00 57.11 C +ATOM 21505 N LYS L 73 71.355 27.826 58.894 1.00 80.71 N +ATOM 21506 CA LYS L 73 72.641 27.375 58.341 1.00 75.96 C +ATOM 21507 C LYS L 73 73.772 28.297 58.743 1.00 86.83 C +ATOM 21508 O LYS L 73 74.826 27.823 59.181 1.00117.93 O +ATOM 21509 CB LYS L 73 72.615 27.286 56.824 1.00 62.42 C +ATOM 21510 CG LYS L 73 73.818 26.552 56.250 1.00 67.15 C +ATOM 21511 CD LYS L 73 73.758 26.482 54.724 1.00 90.74 C +ATOM 21512 CE LYS L 73 75.143 26.392 54.094 1.00114.79 C +ATOM 21513 NZ LYS L 73 75.397 25.091 53.407 1.00126.93 N +ATOM 21514 N ASP L 74 73.541 29.609 58.647 1.00 80.88 N +ATOM 21515 CA ASP L 74 74.577 30.598 58.979 1.00102.61 C +ATOM 21516 C ASP L 74 75.029 30.538 60.443 1.00121.82 C +ATOM 21517 O ASP L 74 76.197 30.805 60.745 1.00118.75 O +ATOM 21518 CB ASP L 74 74.081 32.001 58.686 1.00107.98 C +ATOM 21519 CG ASP L 74 73.875 32.257 57.195 1.00122.34 C +ATOM 21520 OD1 ASP L 74 74.599 31.671 56.344 1.00174.26 O +ATOM 21521 OD2 ASP L 74 73.044 33.135 56.883 1.00111.44 O +ATOM 21522 N SER L 75 74.133 30.075 61.322 1.00123.09 N +ATOM 21523 CA SER L 75 74.429 29.940 62.752 1.00 95.13 C +ATOM 21524 C SER L 75 75.544 28.919 63.063 1.00102.73 C +ATOM 21525 O SER L 75 76.208 29.013 64.093 1.00 81.87 O +ATOM 21526 CB SER L 75 73.172 29.530 63.510 1.00 84.33 C +ATOM 21527 OG SER L 75 73.007 28.113 63.536 1.00 73.60 O +ATOM 21528 N ARG L 76 75.705 27.930 62.178 1.00 91.26 N +ATOM 21529 CA ARG L 76 76.688 26.856 62.319 1.00 73.18 C +ATOM 21530 C ARG L 76 76.359 26.016 63.516 1.00 61.75 C +ATOM 21531 O ARG L 76 77.244 25.523 64.206 1.00 49.05 O +ATOM 21532 CB ARG L 76 78.112 27.397 62.401 1.00 79.83 C +ATOM 21533 CG ARG L 76 78.587 28.164 61.168 1.00 96.35 C +ATOM 21534 CD ARG L 76 80.027 28.631 61.343 1.00116.67 C +ATOM 21535 NE ARG L 76 80.135 29.679 62.372 1.00141.70 N +ATOM 21536 CZ ARG L 76 80.427 29.473 63.660 1.00151.64 C +ATOM 21537 NH1 ARG L 76 80.671 28.250 64.131 1.00155.29 N +ATOM 21538 NH2 ARG L 76 80.485 30.506 64.486 1.00124.55 N +ATOM 21539 N TRP L 77 75.063 25.845 63.734 1.00 67.59 N +ATOM 21540 CA TRP L 77 74.545 24.910 64.730 1.00 85.72 C +ATOM 21541 C TRP L 77 73.747 23.778 64.063 1.00 74.30 C +ATOM 21542 O TRP L 77 73.760 22.636 64.530 1.00 57.88 O +ATOM 21543 CB TRP L 77 73.641 25.659 65.725 1.00 82.21 C +ATOM 21544 CG TRP L 77 74.347 26.181 66.952 1.00 75.51 C +ATOM 21545 CD1 TRP L 77 75.157 27.260 67.025 1.00 83.01 C +ATOM 21546 CD2 TRP L 77 74.303 25.626 68.259 1.00 73.56 C +ATOM 21547 NE1 TRP L 77 75.632 27.410 68.297 1.00 76.16 N +ATOM 21548 CE2 TRP L 77 75.125 26.413 69.076 1.00 67.63 C +ATOM 21549 CE3 TRP L 77 73.646 24.531 68.817 1.00100.74 C +ATOM 21550 CZ2 TRP L 77 75.293 26.163 70.425 1.00 80.23 C +ATOM 21551 CZ3 TRP L 77 73.818 24.274 70.167 1.00109.51 C +ATOM 21552 CH2 TRP L 77 74.646 25.081 70.955 1.00 98.61 C +ATOM 21553 N PHE L 78 73.089 24.116 62.958 1.00 67.38 N +ATOM 21554 CA PHE L 78 72.186 23.213 62.278 1.00 75.78 C +ATOM 21555 C PHE L 78 72.607 22.933 60.825 1.00 77.05 C +ATOM 21556 O PHE L 78 73.055 23.830 60.110 1.00 58.59 O +ATOM 21557 CB PHE L 78 70.789 23.824 62.239 1.00 82.89 C +ATOM 21558 CG PHE L 78 70.257 24.207 63.580 1.00 71.48 C +ATOM 21559 CD1 PHE L 78 69.781 23.245 64.445 1.00 82.34 C +ATOM 21560 CD2 PHE L 78 70.184 25.517 63.948 1.00 60.17 C +ATOM 21561 CE1 PHE L 78 69.271 23.601 65.674 1.00 75.61 C +ATOM 21562 CE2 PHE L 78 69.677 25.876 65.176 1.00 54.10 C +ATOM 21563 CZ PHE L 78 69.187 24.927 66.022 1.00 57.20 C +ATOM 21564 N ILE L 79 72.381 21.691 60.387 1.00 67.87 N +ATOM 21565 CA ILE L 79 72.365 21.333 58.980 1.00 56.26 C +ATOM 21566 C ILE L 79 70.922 21.293 58.546 1.00 52.73 C +ATOM 21567 O ILE L 79 70.083 20.604 59.185 1.00 74.84 O +ATOM 21568 CB ILE L 79 72.925 19.926 58.768 1.00 65.77 C +ATOM 21569 CG1 ILE L 79 74.256 19.768 59.485 1.00 63.47 C +ATOM 21570 CG2 ILE L 79 73.094 19.631 57.275 1.00 88.62 C +ATOM 21571 CD1 ILE L 79 74.609 18.325 59.798 1.00 67.81 C +ATOM 21572 N PRO L 80 70.598 22.069 57.515 1.00 41.49 N +ATOM 21573 CA PRO L 80 69.205 21.992 57.146 1.00 48.49 C +ATOM 21574 C PRO L 80 69.027 20.898 56.114 1.00 51.67 C +ATOM 21575 O PRO L 80 69.764 20.881 55.139 1.00 79.71 O +ATOM 21576 CB PRO L 80 68.908 23.410 56.591 1.00 40.05 C +ATOM 21577 CG PRO L 80 69.898 24.274 57.240 1.00 36.00 C +ATOM 21578 CD PRO L 80 71.137 23.395 57.232 1.00 37.60 C +ATOM 21579 N LEU L 81 67.994 20.087 56.286 1.00 45.27 N +ATOM 21580 CA LEU L 81 67.561 19.192 55.271 1.00 60.82 C +ATOM 21581 C LEU L 81 66.445 19.757 54.399 1.00 75.03 C +ATOM 21582 O LEU L 81 65.610 20.555 54.880 1.00 77.82 O +ATOM 21583 CB LEU L 81 67.095 17.927 55.914 1.00 70.88 C +ATOM 21584 CG LEU L 81 68.171 17.396 56.868 1.00 83.70 C +ATOM 21585 CD1 LEU L 81 67.596 16.190 57.566 1.00 95.89 C +ATOM 21586 CD2 LEU L 81 69.418 17.013 56.117 1.00 87.38 C +ATOM 21587 N GLU L 82 66.537 19.463 53.088 1.00 90.35 N +ATOM 21588 CA GLU L 82 65.692 20.119 52.067 1.00 85.86 C +ATOM 21589 C GLU L 82 64.360 19.464 52.007 1.00 74.36 C +ATOM 21590 O GLU L 82 64.245 18.299 51.585 1.00 78.13 O +ATOM 21591 CB GLU L 82 66.330 20.128 50.664 1.00 85.06 C +ATOM 21592 CG GLU L 82 65.452 20.744 49.565 1.00 76.75 C +ATOM 21593 CD GLU L 82 65.257 22.273 49.660 1.00 92.90 C +ATOM 21594 OE1 GLU L 82 64.929 22.831 50.750 1.00113.98 O +ATOM 21595 OE2 GLU L 82 65.408 22.953 48.612 1.00115.75 O +ATOM 21596 N ARG L 83 63.359 20.199 52.504 1.00 80.28 N +ATOM 21597 CA ARG L 83 61.971 19.750 52.472 1.00 84.52 C +ATOM 21598 C ARG L 83 61.053 20.753 51.761 1.00 76.85 C +ATOM 21599 O ARG L 83 59.989 20.368 51.283 1.00 79.98 O +ATOM 21600 CB ARG L 83 61.447 19.455 53.881 1.00 74.28 C +ATOM 21601 CG ARG L 83 62.271 18.441 54.664 1.00 73.93 C +ATOM 21602 CD ARG L 83 62.162 17.017 54.103 1.00 70.54 C +ATOM 21603 NE ARG L 83 62.773 16.065 55.033 1.00 58.64 N +ATOM 21604 CZ ARG L 83 63.992 15.555 54.932 1.00 51.82 C +ATOM 21605 NH1 ARG L 83 64.755 15.816 53.885 1.00 61.42 N +ATOM 21606 NH2 ARG L 83 64.470 14.830 55.920 1.00 48.87 N +ATOM 21607 N GLN L 84 61.467 22.006 51.616 1.00 74.59 N +ATOM 21608 CA GLN L 84 60.607 22.942 50.883 1.00 88.46 C +ATOM 21609 C GLN L 84 60.353 22.416 49.477 1.00 86.04 C +ATOM 21610 O GLN L 84 59.249 22.495 48.954 1.00 92.15 O +ATOM 21611 CB GLN L 84 61.159 24.377 50.867 1.00 89.00 C +ATOM 21612 CG GLN L 84 60.075 25.466 50.832 1.00 89.84 C +ATOM 21613 CD GLN L 84 60.658 26.871 50.743 1.00135.96 C +ATOM 21614 OE1 GLN L 84 61.718 27.153 51.308 1.00185.77 O +ATOM 21615 NE2 GLN L 84 59.974 27.759 50.027 1.00144.55 N +ATOM 21616 N GLY L 85 61.376 21.876 48.847 1.00 86.87 N +ATOM 21617 CA GLY L 85 61.195 21.397 47.496 1.00 87.10 C +ATOM 21618 C GLY L 85 61.356 19.895 47.466 1.00 61.06 C +ATOM 21619 O GLY L 85 61.848 19.361 46.465 1.00 57.03 O +ATOM 21620 N LEU L 86 60.771 19.221 48.452 1.00 49.78 N +ATOM 21621 CA LEU L 86 60.943 17.775 48.601 1.00 54.58 C +ATOM 21622 C LEU L 86 60.466 16.985 47.375 1.00 88.49 C +ATOM 21623 O LEU L 86 61.112 16.005 46.969 1.00126.73 O +ATOM 21624 CB LEU L 86 60.200 17.265 49.823 1.00 45.90 C +ATOM 21625 CG LEU L 86 60.147 15.786 50.082 1.00 55.07 C +ATOM 21626 CD1 LEU L 86 61.539 15.161 50.246 1.00 69.30 C +ATOM 21627 CD2 LEU L 86 59.297 15.517 51.322 1.00 57.96 C +ATOM 21628 N GLN L 87 59.395 17.455 46.725 1.00 91.67 N +ATOM 21629 CA GLN L 87 58.822 16.729 45.599 1.00 84.80 C +ATOM 21630 C GLN L 87 59.812 16.585 44.405 1.00100.95 C +ATOM 21631 O GLN L 87 60.000 15.492 43.826 1.00 95.17 O +ATOM 21632 CB GLN L 87 57.521 17.398 45.170 1.00 81.84 C +ATOM 21633 CG GLN L 87 56.464 16.411 44.662 1.00 92.31 C +ATOM 21634 CD GLN L 87 56.345 15.149 45.517 1.00 85.87 C +ATOM 21635 OE1 GLN L 87 56.096 15.224 46.721 1.00130.04 O +ATOM 21636 NE2 GLN L 87 56.518 13.983 44.897 1.00 88.32 N +ATOM 21637 N ASN L 88 60.500 17.678 44.093 1.00 86.83 N +ATOM 21638 CA ASN L 88 61.524 17.669 43.055 1.00 74.24 C +ATOM 21639 C ASN L 88 62.707 16.778 43.393 1.00 77.71 C +ATOM 21640 O ASN L 88 63.309 16.137 42.505 1.00 85.17 O +ATOM 21641 CB ASN L 88 62.050 19.072 42.858 1.00 65.86 C +ATOM 21642 CG ASN L 88 60.941 20.054 42.570 1.00 73.65 C +ATOM 21643 OD1 ASN L 88 60.003 19.721 41.848 1.00 67.78 O +ATOM 21644 ND2 ASN L 88 61.068 21.283 43.084 1.00 61.71 N +ATOM 21645 N LEU L 89 63.093 16.800 44.668 1.00 62.14 N +ATOM 21646 CA LEU L 89 64.179 15.988 45.141 1.00 59.28 C +ATOM 21647 C LEU L 89 63.839 14.491 44.860 1.00 65.03 C +ATOM 21648 O LEU L 89 64.678 13.695 44.384 1.00 62.40 O +ATOM 21649 CB LEU L 89 64.386 16.264 46.617 1.00 64.86 C +ATOM 21650 CG LEU L 89 65.783 16.111 47.210 1.00 88.70 C +ATOM 21651 CD1 LEU L 89 65.810 14.985 48.245 1.00 96.75 C +ATOM 21652 CD2 LEU L 89 66.845 15.862 46.147 1.00 78.86 C +ATOM 21653 N LEU L 90 62.589 14.125 45.108 1.00 69.92 N +ATOM 21654 CA LEU L 90 62.181 12.735 44.987 1.00 74.92 C +ATOM 21655 C LEU L 90 62.115 12.356 43.520 1.00 68.28 C +ATOM 21656 O LEU L 90 62.320 11.178 43.144 1.00 50.34 O +ATOM 21657 CB LEU L 90 60.825 12.522 45.675 1.00 69.47 C +ATOM 21658 CG LEU L 90 60.844 12.796 47.178 1.00 57.96 C +ATOM 21659 CD1 LEU L 90 59.410 12.995 47.628 1.00 65.06 C +ATOM 21660 CD2 LEU L 90 61.521 11.647 47.925 1.00 49.84 C +ATOM 21661 N ASN L 91 61.806 13.355 42.703 1.00 64.65 N +ATOM 21662 CA ASN L 91 61.719 13.148 41.279 1.00 84.11 C +ATOM 21663 C ASN L 91 63.094 12.896 40.668 1.00 76.18 C +ATOM 21664 O ASN L 91 63.277 11.921 39.904 1.00 57.71 O +ATOM 21665 CB ASN L 91 61.061 14.350 40.615 1.00102.80 C +ATOM 21666 CG ASN L 91 59.898 13.938 39.742 1.00120.44 C +ATOM 21667 OD1 ASN L 91 59.052 13.156 40.198 1.00124.98 O +ATOM 21668 ND2 ASN L 91 59.985 14.238 38.429 1.00126.05 N +ATOM 21669 N GLU L 92 64.054 13.759 40.995 1.00 55.15 N +ATOM 21670 CA GLU L 92 65.437 13.511 40.554 1.00 61.69 C +ATOM 21671 C GLU L 92 65.994 12.133 41.002 1.00 61.30 C +ATOM 21672 O GLU L 92 66.710 11.452 40.253 1.00 42.31 O +ATOM 21673 CB GLU L 92 66.378 14.587 41.055 1.00 61.59 C +ATOM 21674 CG GLU L 92 66.521 15.751 40.119 1.00 65.89 C +ATOM 21675 CD GLU L 92 66.896 15.336 38.682 1.00 76.31 C +ATOM 21676 OE1 GLU L 92 67.970 14.722 38.459 1.00 75.79 O +ATOM 21677 OE2 GLU L 92 66.178 15.743 37.755 1.00 77.86 O +ATOM 21678 N ARG L 93 65.595 11.709 42.197 1.00 61.18 N +ATOM 21679 CA ARG L 93 65.950 10.390 42.675 1.00 69.00 C +ATOM 21680 C ARG L 93 65.244 9.247 41.870 1.00 77.28 C +ATOM 21681 O ARG L 93 65.851 8.201 41.605 1.00 59.66 O +ATOM 21682 CB ARG L 93 65.687 10.294 44.178 1.00 57.23 C +ATOM 21683 CG ARG L 93 66.615 11.174 44.944 1.00 51.88 C +ATOM 21684 CD ARG L 93 66.201 11.409 46.384 1.00 64.73 C +ATOM 21685 NE ARG L 93 66.964 10.587 47.327 1.00 71.07 N +ATOM 21686 CZ ARG L 93 66.598 9.397 47.764 1.00 61.94 C +ATOM 21687 NH1 ARG L 93 65.427 8.864 47.408 1.00 56.55 N +ATOM 21688 NH2 ARG L 93 67.390 8.777 48.628 1.00 64.14 N +ATOM 21689 N LYS L 94 64.014 9.471 41.426 1.00 69.85 N +ATOM 21690 CA LYS L 94 63.387 8.533 40.517 1.00 82.88 C +ATOM 21691 C LYS L 94 64.208 8.410 39.235 1.00 74.38 C +ATOM 21692 O LYS L 94 64.338 7.308 38.663 1.00 62.12 O +ATOM 21693 CB LYS L 94 61.965 8.981 40.173 1.00110.82 C +ATOM 21694 CG LYS L 94 60.891 8.516 41.146 1.00142.07 C +ATOM 21695 CD LYS L 94 59.561 9.187 40.819 1.00162.66 C +ATOM 21696 CE LYS L 94 58.362 8.447 41.400 1.00163.63 C +ATOM 21697 NZ LYS L 94 57.153 9.312 41.355 1.00165.48 N +ATOM 21698 N ILE L 95 64.680 9.551 38.728 1.00 65.88 N +ATOM 21699 CA ILE L 95 65.343 9.568 37.419 1.00 65.23 C +ATOM 21700 C ILE L 95 66.697 8.909 37.488 1.00 56.77 C +ATOM 21701 O ILE L 95 67.093 8.169 36.558 1.00 39.31 O +ATOM 21702 CB ILE L 95 65.538 10.980 36.849 1.00 66.08 C +ATOM 21703 CG1 ILE L 95 64.233 11.785 36.903 1.00 56.77 C +ATOM 21704 CG2 ILE L 95 65.968 10.846 35.393 1.00 97.67 C +ATOM 21705 CD1 ILE L 95 64.220 13.049 36.060 1.00 53.12 C +ATOM 21706 N ILE L 96 67.383 9.188 38.602 1.00 59.43 N +ATOM 21707 CA ILE L 96 68.606 8.482 38.953 1.00 55.12 C +ATOM 21708 C ILE L 96 68.368 6.973 38.951 1.00 53.77 C +ATOM 21709 O ILE L 96 69.023 6.252 38.194 1.00 74.43 O +ATOM 21710 CB ILE L 96 69.184 8.898 40.313 1.00 41.29 C +ATOM 21711 CG1 ILE L 96 69.610 10.350 40.275 1.00 37.49 C +ATOM 21712 CG2 ILE L 96 70.384 8.033 40.657 1.00 30.98 C +ATOM 21713 CD1 ILE L 96 70.237 10.802 41.568 1.00 44.13 C +ATOM 21714 N ARG L 97 67.438 6.506 39.768 1.00 51.24 N +ATOM 21715 CA ARG L 97 67.221 5.060 39.924 1.00 78.21 C +ATOM 21716 C ARG L 97 66.807 4.404 38.606 1.00 84.13 C +ATOM 21717 O ARG L 97 67.127 3.244 38.343 1.00 64.83 O +ATOM 21718 CB ARG L 97 66.155 4.772 40.983 1.00 98.86 C +ATOM 21719 CG ARG L 97 66.701 4.296 42.325 1.00100.16 C +ATOM 21720 CD ARG L 97 65.568 3.981 43.291 1.00105.06 C +ATOM 21721 NE ARG L 97 65.034 5.183 43.938 1.00101.92 N +ATOM 21722 CZ ARG L 97 65.395 5.623 45.145 1.00114.81 C +ATOM 21723 NH1 ARG L 97 66.304 4.953 45.875 1.00105.60 N +ATOM 21724 NH2 ARG L 97 64.852 6.748 45.628 1.00102.62 N +ATOM 21725 N ALA L 98 66.129 5.167 37.759 1.00 92.54 N +ATOM 21726 CA ALA L 98 65.742 4.662 36.453 1.00 99.66 C +ATOM 21727 C ALA L 98 66.937 4.605 35.502 1.00 75.17 C +ATOM 21728 O ALA L 98 66.988 3.772 34.590 1.00 43.27 O +ATOM 21729 CB ALA L 98 64.642 5.533 35.879 1.00119.68 C +ATOM 21730 N ALA L 99 67.902 5.487 35.745 1.00 78.31 N +ATOM 21731 CA ALA L 99 69.113 5.561 34.926 1.00 97.92 C +ATOM 21732 C ALA L 99 70.001 4.333 35.128 1.00 86.24 C +ATOM 21733 O ALA L 99 70.469 3.724 34.169 1.00117.51 O +ATOM 21734 CB ALA L 99 69.896 6.845 35.222 1.00 99.78 C +ATOM 21735 N GLN L 100 70.259 4.003 36.379 1.00 70.62 N +ATOM 21736 CA GLN L 100 71.387 3.141 36.705 1.00 87.39 C +ATOM 21737 C GLN L 100 70.955 1.771 37.158 1.00 84.37 C +ATOM 21738 O GLN L 100 71.793 0.966 37.597 1.00138.51 O +ATOM 21739 CB GLN L 100 72.323 3.795 37.760 1.00 89.48 C +ATOM 21740 CG GLN L 100 71.624 4.503 38.899 1.00 69.26 C +ATOM 21741 CD GLN L 100 72.455 5.615 39.493 1.00 52.20 C +ATOM 21742 OE1 GLN L 100 72.822 6.610 38.832 1.00 29.41 O +ATOM 21743 NE2 GLN L 100 72.734 5.463 40.784 1.00 55.34 N +ATOM 21744 N GLU L 101 69.666 1.495 37.054 1.00 80.65 N +ATOM 21745 CA GLU L 101 69.138 0.210 37.527 1.00100.96 C +ATOM 21746 C GLU L 101 69.619 -0.969 36.679 1.00104.43 C +ATOM 21747 O GLU L 101 69.661 -2.115 37.156 1.00 69.81 O +ATOM 21748 CB GLU L 101 67.611 0.234 37.575 1.00106.76 C +ATOM 21749 CG GLU L 101 66.944 0.700 36.290 1.00 99.09 C +ATOM 21750 CD GLU L 101 65.429 0.619 36.363 1.00 93.81 C +ATOM 21751 OE1 GLU L 101 64.892 0.531 37.480 1.00111.47 O +ATOM 21752 OE2 GLU L 101 64.765 0.651 35.305 1.00117.98 O +ATOM 21753 N ASN L 102 70.008 -0.689 35.436 1.00104.60 N +ATOM 21754 CA ASN L 102 70.453 -1.749 34.541 1.00112.75 C +ATOM 21755 C ASN L 102 71.959 -2.010 34.573 1.00123.89 C +ATOM 21756 O ASN L 102 72.448 -2.896 33.878 1.00116.97 O +ATOM 21757 CB ASN L 102 70.009 -1.434 33.125 1.00106.49 C +ATOM 21758 CG ASN L 102 68.513 -1.578 32.958 1.00108.03 C +ATOM 21759 OD1 ASN L 102 67.991 -2.693 32.814 1.00 99.53 O +ATOM 21760 ND2 ASN L 102 67.809 -0.452 33.008 1.00 97.58 N +ATOM 21761 N GLY L 103 72.696 -1.223 35.350 1.00131.18 N +ATOM 21762 CA GLY L 103 74.150 -1.363 35.422 1.00112.71 C +ATOM 21763 C GLY L 103 74.880 -1.162 34.103 1.00116.24 C +ATOM 21764 O GLY L 103 75.871 -1.838 33.809 1.00158.08 O +ATOM 21765 N THR L 104 74.353 -0.286 33.264 1.00100.91 N +ATOM 21766 CA THR L 104 75.067 0.110 32.075 1.00101.57 C +ATOM 21767 C THR L 104 75.729 1.433 32.344 1.00 99.79 C +ATOM 21768 O THR L 104 76.724 1.745 31.715 1.00115.24 O +ATOM 21769 CB THR L 104 74.150 0.186 30.823 1.00128.32 C +ATOM 21770 OG1 THR L 104 73.129 1.187 30.974 1.00110.46 O +ATOM 21771 CG2 THR L 104 73.484 -1.176 30.565 1.00148.84 C +ATOM 21772 N VAL L 105 75.163 2.235 33.250 1.00 97.63 N +ATOM 21773 CA VAL L 105 75.590 3.649 33.385 1.00110.99 C +ATOM 21774 C VAL L 105 77.063 3.687 33.790 1.00139.62 C +ATOM 21775 O VAL L 105 77.533 2.834 34.559 1.00111.95 O +ATOM 21776 CB VAL L 105 74.701 4.496 34.359 1.00 95.74 C +ATOM 21777 CG1 VAL L 105 75.533 5.502 35.148 1.00 94.75 C +ATOM 21778 CG2 VAL L 105 73.571 5.219 33.607 1.00 65.42 C +ATOM 21779 N ALA L 106 77.781 4.652 33.207 1.00161.73 N +ATOM 21780 CA ALA L 106 79.235 4.744 33.307 1.00145.87 C +ATOM 21781 C ALA L 106 79.657 4.949 34.752 1.00151.27 C +ATOM 21782 O ALA L 106 79.078 5.773 35.461 1.00183.45 O +ATOM 21783 CB ALA L 106 79.745 5.884 32.433 1.00124.86 C +ATOM 21784 N ILE L 107 80.659 4.183 35.182 1.00155.51 N +ATOM 21785 CA ILE L 107 81.092 4.164 36.584 1.00143.91 C +ATOM 21786 C ILE L 107 81.510 5.557 37.107 1.00134.16 C +ATOM 21787 O ILE L 107 81.341 5.867 38.287 1.00108.34 O +ATOM 21788 CB ILE L 107 82.244 3.142 36.787 1.00140.67 C +ATOM 21789 CG1 ILE L 107 82.494 2.878 38.277 1.00126.20 C +ATOM 21790 CG2 ILE L 107 83.522 3.617 36.101 1.00133.83 C +ATOM 21791 CD1 ILE L 107 81.281 2.375 39.036 1.00119.40 C +ATOM 21792 N ASN L 108 82.041 6.394 36.221 1.00141.85 N +ATOM 21793 CA ASN L 108 82.378 7.783 36.556 1.00138.44 C +ATOM 21794 C ASN L 108 81.123 8.621 36.770 1.00141.20 C +ATOM 21795 O ASN L 108 81.099 9.533 37.593 1.00133.67 O +ATOM 21796 CB ASN L 108 83.206 8.416 35.433 1.00151.61 C +ATOM 21797 CG ASN L 108 84.060 7.402 34.697 1.00182.09 C +ATOM 21798 OD1 ASN L 108 85.186 7.113 35.103 1.00192.85 O +ATOM 21799 ND2 ASN L 108 83.530 6.862 33.599 1.00198.36 N +ATOM 21800 N ASN L 109 80.095 8.323 35.984 1.00139.07 N +ATOM 21801 CA ASN L 109 78.864 9.097 35.967 1.00119.19 C +ATOM 21802 C ASN L 109 77.856 8.653 37.024 1.00109.07 C +ATOM 21803 O ASN L 109 76.930 9.400 37.356 1.00148.04 O +ATOM 21804 CB ASN L 109 78.219 9.006 34.589 1.00125.99 C +ATOM 21805 CG ASN L 109 78.153 10.351 33.899 1.00151.38 C +ATOM 21806 OD1 ASN L 109 77.071 10.882 33.650 1.00150.17 O +ATOM 21807 ND2 ASN L 109 79.317 10.919 33.596 1.00173.05 N +ATOM 21808 N ARG L 110 78.060 7.452 37.560 1.00 89.72 N +ATOM 21809 CA ARG L 110 77.145 6.827 38.509 1.00 69.50 C +ATOM 21810 C ARG L 110 76.899 7.728 39.719 1.00 72.45 C +ATOM 21811 O ARG L 110 77.830 8.286 40.307 1.00 68.86 O +ATOM 21812 CB ARG L 110 77.751 5.495 38.996 1.00 83.45 C +ATOM 21813 CG ARG L 110 76.748 4.474 39.503 1.00 99.51 C +ATOM 21814 CD ARG L 110 77.160 3.042 39.175 1.00101.60 C +ATOM 21815 NE ARG L 110 77.997 2.433 40.212 1.00108.76 N +ATOM 21816 CZ ARG L 110 77.685 1.324 40.905 1.00122.48 C +ATOM 21817 NH1 ARG L 110 76.541 0.665 40.683 1.00107.11 N +ATOM 21818 NH2 ARG L 110 78.534 0.860 41.823 1.00100.13 N +ATOM 21819 N ILE L 111 75.639 7.846 40.127 1.00 91.49 N +ATOM 21820 CA ILE L 111 75.287 8.583 41.372 1.00 85.86 C +ATOM 21821 C ILE L 111 74.834 7.590 42.432 1.00 81.00 C +ATOM 21822 O ILE L 111 73.806 6.957 42.244 1.00 91.80 O +ATOM 21823 CB ILE L 111 74.157 9.628 41.152 1.00 70.64 C +ATOM 21824 CG1 ILE L 111 74.653 10.690 40.179 1.00 80.67 C +ATOM 21825 CG2 ILE L 111 73.757 10.262 42.463 1.00 53.56 C +ATOM 21826 CD1 ILE L 111 73.575 11.601 39.636 1.00 70.04 C +ATOM 21827 N PRO L 112 75.579 7.480 43.549 1.00 81.53 N +ATOM 21828 CA PRO L 112 75.232 6.529 44.595 1.00 77.96 C +ATOM 21829 C PRO L 112 74.128 7.085 45.489 1.00 91.84 C +ATOM 21830 O PRO L 112 74.195 8.257 45.914 1.00 83.42 O +ATOM 21831 CB PRO L 112 76.519 6.396 45.378 1.00 72.82 C +ATOM 21832 CG PRO L 112 77.165 7.748 45.248 1.00 87.39 C +ATOM 21833 CD PRO L 112 76.713 8.342 43.940 1.00 89.08 C +ATOM 21834 N LEU L 113 73.071 6.289 45.665 1.00102.37 N +ATOM 21835 CA LEU L 113 71.853 6.753 46.325 1.00 91.99 C +ATOM 21836 C LEU L 113 71.711 6.141 47.685 1.00 98.91 C +ATOM 21837 O LEU L 113 71.968 4.945 47.909 1.00 88.71 O +ATOM 21838 CB LEU L 113 70.597 6.452 45.513 1.00 82.99 C +ATOM 21839 CG LEU L 113 70.213 7.506 44.484 1.00 85.76 C +ATOM 21840 CD1 LEU L 113 68.916 7.083 43.854 1.00 97.79 C +ATOM 21841 CD2 LEU L 113 70.084 8.900 45.061 1.00 86.13 C +ATOM 21842 N GLN L 114 71.274 6.997 48.589 1.00 97.92 N +ATOM 21843 CA GLN L 114 71.327 6.721 49.997 1.00 90.86 C +ATOM 21844 C GLN L 114 70.050 7.322 50.512 1.00 78.36 C +ATOM 21845 O GLN L 114 69.538 8.280 49.935 1.00 60.36 O +ATOM 21846 CB GLN L 114 72.546 7.395 50.643 1.00 87.44 C +ATOM 21847 CG GLN L 114 73.131 6.630 51.826 1.00 82.38 C +ATOM 21848 CD GLN L 114 74.009 7.488 52.751 1.00 91.93 C +ATOM 21849 OE1 GLN L 114 74.297 7.139 53.936 1.00 86.20 O +ATOM 21850 NE2 GLN L 114 74.438 8.633 52.222 1.00 81.12 N +ATOM 21851 N SER L 115 69.516 6.714 51.567 1.00 77.03 N +ATOM 21852 CA SER L 115 68.201 7.075 52.083 1.00 69.60 C +ATOM 21853 C SER L 115 68.233 8.516 52.515 1.00 65.24 C +ATOM 21854 O SER L 115 69.334 9.074 52.744 1.00 66.79 O +ATOM 21855 CB SER L 115 67.834 6.197 53.268 1.00 75.70 C +ATOM 21856 OG SER L 115 68.898 6.172 54.237 1.00 80.58 O +ATOM 21857 N LEU L 116 67.066 9.164 52.544 1.00 63.20 N +ATOM 21858 CA LEU L 116 67.095 10.609 52.655 1.00 72.38 C +ATOM 21859 C LEU L 116 67.448 10.920 54.096 1.00 83.08 C +ATOM 21860 O LEU L 116 66.838 10.321 54.970 1.00 88.56 O +ATOM 21861 CB LEU L 116 65.764 11.219 52.286 1.00 60.72 C +ATOM 21862 CG LEU L 116 65.345 11.148 50.812 1.00 62.06 C +ATOM 21863 CD1 LEU L 116 64.448 9.934 50.577 1.00 66.80 C +ATOM 21864 CD2 LEU L 116 64.621 12.442 50.438 1.00 63.54 C +ATOM 21865 N THR L 117 68.501 11.727 54.322 1.00 68.08 N +ATOM 21866 CA THR L 117 68.971 12.062 55.672 1.00 60.45 C +ATOM 21867 C THR L 117 67.840 12.674 56.418 1.00 61.20 C +ATOM 21868 O THR L 117 67.083 13.479 55.851 1.00 42.77 O +ATOM 21869 CB THR L 117 70.068 13.117 55.666 1.00 69.14 C +ATOM 21870 OG1 THR L 117 71.140 12.667 54.835 1.00129.59 O +ATOM 21871 CG2 THR L 117 70.587 13.346 57.056 1.00 75.96 C +ATOM 21872 N ALA L 118 67.616 12.171 57.635 1.00 73.99 N +ATOM 21873 CA ALA L 118 66.369 12.457 58.368 1.00 85.81 C +ATOM 21874 C ALA L 118 66.612 13.274 59.606 1.00 60.15 C +ATOM 21875 O ALA L 118 67.554 12.995 60.348 1.00 52.11 O +ATOM 21876 CB ALA L 118 65.645 11.172 58.754 1.00116.30 C +ATOM 21877 N ALA L 119 65.704 14.218 59.840 1.00 43.25 N +ATOM 21878 CA ALA L 119 65.858 15.199 60.888 1.00 54.04 C +ATOM 21879 C ALA L 119 65.332 14.686 62.220 1.00 77.76 C +ATOM 21880 O ALA L 119 64.426 13.822 62.258 1.00 65.36 O +ATOM 21881 CB ALA L 119 65.131 16.465 60.507 1.00 55.28 C +ATOM 21882 N ASN L 120 65.848 15.243 63.325 1.00 98.97 N +ATOM 21883 CA ASN L 120 65.296 14.915 64.655 1.00122.55 C +ATOM 21884 C ASN L 120 64.293 15.953 65.140 1.00 87.09 C +ATOM 21885 O ASN L 120 63.248 15.621 65.709 1.00 74.07 O +ATOM 21886 CB ASN L 120 66.408 14.741 65.710 1.00132.91 C +ATOM 21887 CG ASN L 120 65.863 14.403 67.106 1.00131.15 C +ATOM 21888 OD1 ASN L 120 64.855 13.684 67.255 1.00121.27 O +ATOM 21889 ND2 ASN L 120 66.528 14.933 68.133 1.00109.70 N +ATOM 21890 N ILE L 121 64.669 17.212 65.014 1.00 65.37 N +ATOM 21891 CA ILE L 121 63.762 18.280 65.382 1.00 59.79 C +ATOM 21892 C ILE L 121 63.401 18.933 64.106 1.00 48.98 C +ATOM 21893 O ILE L 121 64.241 19.111 63.234 1.00 66.31 O +ATOM 21894 CB ILE L 121 64.370 19.287 66.419 1.00 58.72 C +ATOM 21895 CG1 ILE L 121 65.446 20.177 65.815 1.00 46.41 C +ATOM 21896 CG2 ILE L 121 64.928 18.532 67.644 1.00 76.57 C +ATOM 21897 CD1 ILE L 121 65.015 21.596 65.681 1.00 39.30 C +ATOM 21898 N MET L 122 62.152 19.277 63.973 1.00 45.67 N +ATOM 21899 CA MET L 122 61.808 20.210 62.944 1.00 66.95 C +ATOM 21900 C MET L 122 61.201 21.504 63.521 1.00 67.97 C +ATOM 21901 O MET L 122 60.593 21.500 64.579 1.00128.54 O +ATOM 21902 CB MET L 122 60.879 19.540 61.946 1.00 81.39 C +ATOM 21903 CG MET L 122 59.590 19.003 62.531 1.00120.08 C +ATOM 21904 SD MET L 122 58.318 18.891 61.239 1.00100.51 S +ATOM 21905 CE MET L 122 56.917 19.562 62.197 1.00152.27 C +ATOM 21906 N VAL L 123 61.514 22.635 62.896 1.00 62.89 N +ATOM 21907 CA VAL L 123 61.082 23.943 63.383 1.00 50.83 C +ATOM 21908 C VAL L 123 60.169 24.535 62.375 1.00 49.96 C +ATOM 21909 O VAL L 123 60.570 24.753 61.229 1.00 52.04 O +ATOM 21910 CB VAL L 123 62.274 24.944 63.676 1.00 37.06 C +ATOM 21911 CG1 VAL L 123 63.359 24.816 62.652 1.00 31.22 C +ATOM 21912 CG2 VAL L 123 61.783 26.383 63.825 1.00 26.13 C +ATOM 21913 N GLU L 124 58.967 24.872 62.818 1.00 55.24 N +ATOM 21914 CA GLU L 124 58.084 25.684 61.994 1.00 75.21 C +ATOM 21915 C GLU L 124 57.584 26.922 62.709 1.00 75.16 C +ATOM 21916 O GLU L 124 57.849 27.120 63.882 1.00 94.64 O +ATOM 21917 CB GLU L 124 56.894 24.868 61.541 1.00 72.77 C +ATOM 21918 CG GLU L 124 56.483 23.790 62.500 1.00 60.78 C +ATOM 21919 CD GLU L 124 55.602 22.782 61.812 1.00 75.77 C +ATOM 21920 OE1 GLU L 124 55.826 22.478 60.625 1.00 64.05 O +ATOM 21921 OE2 GLU L 124 54.649 22.301 62.452 1.00127.93 O +ATOM 21922 N GLY L 125 56.964 27.817 61.945 1.00 78.44 N +ATOM 21923 CA GLY L 125 56.560 29.096 62.471 1.00 89.28 C +ATOM 21924 C GLY L 125 55.715 29.857 61.486 1.00 88.84 C +ATOM 21925 O GLY L 125 55.114 29.276 60.573 1.00112.64 O +ATOM 21926 N SER L 126 55.609 31.162 61.696 1.00 64.18 N +ATOM 21927 CA SER L 126 54.638 31.938 60.949 1.00 73.63 C +ATOM 21928 C SER L 126 54.992 33.370 61.077 1.00 63.51 C +ATOM 21929 O SER L 126 55.451 33.805 62.123 1.00 74.81 O +ATOM 21930 CB SER L 126 53.177 31.726 61.448 1.00 87.86 C +ATOM 21931 OG SER L 126 52.929 30.414 61.990 1.00 75.13 O +ATOM 21932 N ILE L 127 54.721 34.137 60.038 1.00 74.67 N +ATOM 21933 CA ILE L 127 54.726 35.580 60.191 1.00 91.12 C +ATOM 21934 C ILE L 127 53.391 35.916 60.840 1.00 81.91 C +ATOM 21935 O ILE L 127 52.379 36.015 60.173 1.00103.56 O +ATOM 21936 CB ILE L 127 54.943 36.346 58.851 1.00 92.10 C +ATOM 21937 CG1 ILE L 127 56.343 36.050 58.283 1.00 93.80 C +ATOM 21938 CG2 ILE L 127 54.759 37.855 59.044 1.00 71.51 C +ATOM 21939 CD1 ILE L 127 56.413 36.068 56.772 1.00 94.67 C +ATOM 21940 N ILE L 128 53.439 36.185 62.132 1.00 79.44 N +ATOM 21941 CA ILE L 128 52.280 36.615 62.900 1.00 75.19 C +ATOM 21942 C ILE L 128 52.271 38.153 62.894 1.00 94.28 C +ATOM 21943 O ILE L 128 53.105 38.848 63.507 1.00106.42 O +ATOM 21944 CB ILE L 128 52.372 36.052 64.320 1.00 78.95 C +ATOM 21945 CG1 ILE L 128 53.716 36.412 64.992 1.00 70.08 C +ATOM 21946 CG2 ILE L 128 52.358 34.544 64.273 1.00 99.38 C +ATOM 21947 CD1 ILE L 128 53.650 36.407 66.510 1.00 63.04 C +ATOM 21948 N GLY L 129 51.463 38.694 62.010 1.00114.68 N +ATOM 21949 CA GLY L 129 51.181 40.118 62.062 1.00133.21 C +ATOM 21950 C GLY L 129 52.125 41.085 61.355 1.00124.86 C +ATOM 21951 O GLY L 129 53.360 41.009 61.446 1.00103.06 O +ATOM 21952 N TYR L 130 51.501 42.022 60.653 1.00126.35 N +ATOM 21953 CA TYR L 130 52.152 43.243 60.216 1.00118.25 C +ATOM 21954 C TYR L 130 51.124 44.340 60.410 1.00 96.18 C +ATOM 21955 O TYR L 130 50.137 44.384 59.730 1.00102.36 O +ATOM 21956 CB TYR L 130 52.565 43.127 58.741 1.00114.33 C +ATOM 21957 CG TYR L 130 53.153 44.385 58.114 1.00 98.40 C +ATOM 21958 CD1 TYR L 130 52.360 45.490 57.835 1.00 98.82 C +ATOM 21959 CD2 TYR L 130 54.494 44.432 57.733 1.00 94.45 C +ATOM 21960 CE1 TYR L 130 52.895 46.625 57.236 1.00104.25 C +ATOM 21961 CE2 TYR L 130 55.034 45.556 57.134 1.00101.95 C +ATOM 21962 CZ TYR L 130 54.233 46.652 56.893 1.00101.88 C +ATOM 21963 OH TYR L 130 54.795 47.766 56.313 1.00101.43 O +ATOM 21964 N GLU L 131 51.333 45.186 61.398 1.00 91.34 N +ATOM 21965 CA GLU L 131 50.528 46.391 61.543 1.00 82.72 C +ATOM 21966 C GLU L 131 51.275 47.562 60.929 1.00 73.15 C +ATOM 21967 O GLU L 131 52.509 47.594 60.943 1.00 69.64 O +ATOM 21968 CB GLU L 131 50.248 46.633 63.027 1.00110.94 C +ATOM 21969 CG GLU L 131 49.231 47.713 63.339 1.00100.16 C +ATOM 21970 CD GLU L 131 47.786 47.203 63.333 1.00111.89 C +ATOM 21971 OE1 GLU L 131 47.557 46.001 63.619 1.00126.09 O +ATOM 21972 OE2 GLU L 131 46.874 48.022 63.074 1.00 97.37 O +ATOM 21973 N SER L 132 50.538 48.513 60.374 1.00 89.13 N +ATOM 21974 CA SER L 132 51.148 49.585 59.597 1.00104.05 C +ATOM 21975 C SER L 132 50.883 50.972 60.196 1.00111.43 C +ATOM 21976 O SER L 132 49.775 51.261 60.658 1.00150.60 O +ATOM 21977 CB SER L 132 50.652 49.516 58.150 1.00100.67 C +ATOM 21978 OG SER L 132 49.851 50.640 57.830 1.00126.34 O +ATOM 21979 N ASN L 133 51.889 51.842 60.134 1.00102.89 N +ATOM 21980 CA ASN L 133 51.853 53.133 60.832 1.00117.02 C +ATOM 21981 C ASN L 133 51.389 52.949 62.268 1.00130.63 C +ATOM 21982 O ASN L 133 50.435 53.589 62.719 1.00147.77 O +ATOM 21983 CB ASN L 133 50.954 54.149 60.120 1.00 98.33 C +ATOM 21984 CG ASN L 133 51.421 54.434 58.702 1.00100.48 C +ATOM 21985 OD1 ASN L 133 52.618 54.385 58.388 1.00108.40 O +ATOM 21986 ND2 ASN L 133 50.477 54.728 57.839 1.00110.63 N +ATOM 21987 N VAL L 134 52.121 52.108 62.987 1.00129.74 N +ATOM 21988 CA VAL L 134 51.862 51.856 64.396 1.00117.72 C +ATOM 21989 C VAL L 134 52.190 53.137 65.177 1.00 97.34 C +ATOM 21990 O VAL L 134 51.495 53.492 66.128 1.00 68.92 O +ATOM 21991 CB VAL L 134 52.711 50.670 64.907 1.00120.76 C +ATOM 21992 CG1 VAL L 134 52.379 50.344 66.345 1.00111.57 C +ATOM 21993 CG2 VAL L 134 52.488 49.442 64.030 1.00123.83 C +ATOM 21994 N LYS L 135 53.208 53.860 64.716 1.00 90.71 N +ATOM 21995 CA LYS L 135 53.400 55.249 65.124 1.00 92.39 C +ATOM 21996 C LYS L 135 53.751 56.134 63.949 1.00 96.62 C +ATOM 21997 O LYS L 135 54.240 55.661 62.900 1.00 93.58 O +ATOM 21998 CB LYS L 135 54.518 55.348 66.158 1.00111.60 C +ATOM 21999 CG LYS L 135 54.224 54.602 67.448 1.00123.48 C +ATOM 22000 CD LYS L 135 55.421 54.646 68.384 1.00118.85 C +ATOM 22001 CE LYS L 135 55.152 53.900 69.677 1.00133.44 C +ATOM 22002 NZ LYS L 135 56.081 54.343 70.744 1.00131.50 N +ATOM 22003 N SER L 136 53.542 57.435 64.137 1.00113.38 N +ATOM 22004 CA SER L 136 53.865 58.422 63.103 1.00132.43 C +ATOM 22005 C SER L 136 53.942 59.844 63.666 1.00104.84 C +ATOM 22006 O SER L 136 53.334 60.135 64.686 1.00 85.31 O +ATOM 22007 CB SER L 136 52.850 58.351 61.952 1.00125.20 C +ATOM 22008 OG SER L 136 52.266 59.623 61.701 1.00140.38 O +ATOM 22009 N GLY L 137 54.704 60.710 62.994 1.00 91.65 N +ATOM 22010 CA GLY L 137 54.804 62.107 63.398 1.00 95.44 C +ATOM 22011 C GLY L 137 55.479 63.014 62.386 1.00105.81 C +ATOM 22012 O GLY L 137 55.885 62.574 61.317 1.00 85.10 O +ATOM 22013 N GLY L 138 55.510 64.313 62.683 1.00145.98 N +ATOM 22014 CA GLY L 138 56.065 65.307 61.757 1.00160.09 C +ATOM 22015 C GLY L 138 56.333 66.664 62.398 1.00138.29 C +ATOM 22016 O GLY L 138 55.582 67.100 63.271 1.00 82.34 O +ATOM 22017 N VAL L 139 57.393 67.328 61.933 1.00118.96 N +ATOM 22018 CA VAL L 139 57.726 68.669 62.379 1.00110.34 C +ATOM 22019 C VAL L 139 58.205 69.514 61.204 1.00115.43 C +ATOM 22020 O VAL L 139 59.133 69.135 60.482 1.00105.42 O +ATOM 22021 CB VAL L 139 58.835 68.646 63.438 1.00122.34 C +ATOM 22022 CG1 VAL L 139 59.255 70.065 63.792 1.00118.02 C +ATOM 22023 CG2 VAL L 139 58.382 67.893 64.687 1.00129.81 C +ATOM 22024 N GLY L 140 57.598 70.688 61.038 1.00126.74 N +ATOM 22025 CA GLY L 140 57.969 71.605 59.952 1.00135.27 C +ATOM 22026 C GLY L 140 57.794 73.074 60.278 1.00128.77 C +ATOM 22027 O GLY L 140 56.873 73.449 61.004 1.00122.46 O +ATOM 22028 N ALA L 141 58.653 73.912 59.700 1.00126.87 N +ATOM 22029 CA ALA L 141 58.501 75.357 59.818 1.00129.08 C +ATOM 22030 C ALA L 141 58.875 76.089 58.526 1.00130.73 C +ATOM 22031 O ALA L 141 59.826 75.726 57.837 1.00115.42 O +ATOM 22032 CB ALA L 141 59.320 75.875 60.988 1.00117.95 C +ATOM 22033 N ARG L 142 58.098 77.111 58.195 1.00134.41 N +ATOM 22034 CA ARG L 142 58.472 78.017 57.135 1.00158.94 C +ATOM 22035 C ARG L 142 58.421 79.446 57.656 1.00210.27 C +ATOM 22036 O ARG L 142 57.585 79.781 58.499 1.00202.86 O +ATOM 22037 CB ARG L 142 57.565 77.854 55.917 1.00152.25 C +ATOM 22038 CG ARG L 142 57.987 78.725 54.735 1.00167.71 C +ATOM 22039 CD ARG L 142 57.905 77.997 53.401 1.00178.90 C +ATOM 22040 NE ARG L 142 56.572 78.052 52.807 1.00178.75 N +ATOM 22041 CZ ARG L 142 56.087 77.173 51.931 1.00165.65 C +ATOM 22042 NH1 ARG L 142 56.810 76.126 51.559 1.00178.68 N +ATOM 22043 NH2 ARG L 142 54.861 77.330 51.444 1.00137.58 N +ATOM 22044 N TYR L 143 59.360 80.265 57.186 1.00244.25 N +ATOM 22045 CA TYR L 143 59.556 81.613 57.716 1.00220.08 C +ATOM 22046 C TYR L 143 59.642 82.646 56.590 1.00180.00 C +ATOM 22047 O TYR L 143 60.729 83.018 56.133 1.00143.49 O +ATOM 22048 CB TYR L 143 60.823 81.647 58.566 1.00230.00 C +ATOM 22049 CG TYR L 143 61.040 82.934 59.291 1.00224.19 C +ATOM 22050 CD1 TYR L 143 60.256 83.272 60.388 1.00200.00 C +ATOM 22051 CD2 TYR L 143 62.065 83.791 58.916 1.00215.14 C +ATOM 22052 CE1 TYR L 143 60.476 84.439 61.087 1.00191.81 C +ATOM 22053 CE2 TYR L 143 62.301 84.959 59.615 1.00211.96 C +ATOM 22054 CZ TYR L 143 61.500 85.279 60.694 1.00206.15 C +ATOM 22055 OH TYR L 143 61.720 86.448 61.380 1.00238.75 O +ATOM 22056 N GLY L 145 60.039 82.926 53.930 1.00199.40 N +ATOM 22057 CA GLY L 145 60.445 82.495 52.598 1.00189.60 C +ATOM 22058 C GLY L 145 61.160 81.155 52.594 1.00196.01 C +ATOM 22059 O GLY L 145 61.161 80.469 51.567 1.00228.78 O +ATOM 22060 N ILE L 146 61.728 80.764 53.737 1.00183.13 N +ATOM 22061 CA ILE L 146 62.578 79.569 53.828 1.00178.98 C +ATOM 22062 C ILE L 146 61.910 78.529 54.735 1.00162.03 C +ATOM 22063 O ILE L 146 61.342 78.878 55.765 1.00128.87 O +ATOM 22064 CB ILE L 146 63.978 79.908 54.396 1.00184.24 C +ATOM 22065 CG1 ILE L 146 64.480 81.247 53.838 1.00163.27 C +ATOM 22066 CG2 ILE L 146 64.974 78.799 54.079 1.00178.33 C +ATOM 22067 CD1 ILE L 146 64.223 82.428 54.752 1.00157.87 C +ATOM 22068 N GLY L 147 61.950 77.255 54.351 1.00149.65 N +ATOM 22069 CA GLY L 147 61.238 76.228 55.121 1.00140.30 C +ATOM 22070 C GLY L 147 61.840 74.841 55.083 1.00125.01 C +ATOM 22071 O GLY L 147 62.507 74.465 54.121 1.00102.92 O +ATOM 22072 N ALA L 148 61.545 74.064 56.114 1.00132.67 N +ATOM 22073 CA ALA L 148 61.881 72.655 56.116 1.00147.68 C +ATOM 22074 C ALA L 148 60.853 71.859 56.914 1.00156.53 C +ATOM 22075 O ALA L 148 60.020 72.417 57.636 1.00142.78 O +ATOM 22076 CB ALA L 148 63.275 72.446 56.683 1.00144.86 C +ATOM 22077 N ASP L 149 60.907 70.542 56.767 1.00156.30 N +ATOM 22078 CA ASP L 149 60.032 69.659 57.529 1.00155.57 C +ATOM 22079 C ASP L 149 60.537 68.222 57.467 1.00140.62 C +ATOM 22080 O ASP L 149 61.102 67.807 56.448 1.00119.65 O +ATOM 22081 CB ASP L 149 58.575 69.771 57.032 1.00152.48 C +ATOM 22082 CG ASP L 149 58.316 68.973 55.787 1.00151.84 C +ATOM 22083 OD1 ASP L 149 58.764 69.406 54.708 1.00165.18 O +ATOM 22084 OD2 ASP L 149 57.682 67.907 55.894 1.00133.95 O +ATOM 22085 N THR L 150 60.322 67.469 58.543 1.00117.67 N +ATOM 22086 CA THR L 150 60.440 66.026 58.459 1.00127.72 C +ATOM 22087 C THR L 150 59.142 65.350 58.881 1.00149.57 C +ATOM 22088 O THR L 150 58.311 65.927 59.585 1.00124.71 O +ATOM 22089 CB THR L 150 61.569 65.484 59.334 1.00125.86 C +ATOM 22090 OG1 THR L 150 61.324 65.843 60.696 1.00145.09 O +ATOM 22091 CG2 THR L 150 62.906 66.031 58.881 1.00122.50 C +ATOM 22092 N GLN L 151 58.948 64.138 58.372 1.00169.33 N +ATOM 22093 CA GLN L 151 57.819 63.303 58.742 1.00150.38 C +ATOM 22094 C GLN L 151 58.310 61.881 58.911 1.00134.60 C +ATOM 22095 O GLN L 151 59.181 61.459 58.173 1.00116.35 O +ATOM 22096 CB GLN L 151 56.754 63.375 57.648 1.00149.26 C +ATOM 22097 CG GLN L 151 56.017 64.698 57.626 1.00148.52 C +ATOM 22098 CD GLN L 151 55.367 64.963 56.292 1.00165.77 C +ATOM 22099 OE1 GLN L 151 54.815 64.051 55.678 1.00131.94 O +ATOM 22100 NE2 GLN L 151 55.440 66.211 55.824 1.00189.46 N +ATOM 22101 N TYR L 152 57.767 61.145 59.877 1.00110.27 N +ATOM 22102 CA TYR L 152 58.157 59.756 60.046 1.00100.97 C +ATOM 22103 C TYR L 152 56.985 58.844 60.319 1.00110.17 C +ATOM 22104 O TYR L 152 55.982 59.260 60.901 1.00112.54 O +ATOM 22105 CB TYR L 152 59.179 59.641 61.149 1.00 95.59 C +ATOM 22106 CG TYR L 152 58.672 59.074 62.457 1.00 91.23 C +ATOM 22107 CD1 TYR L 152 57.730 59.751 63.239 1.00 77.58 C +ATOM 22108 CD2 TYR L 152 59.257 57.941 62.986 1.00 89.07 C +ATOM 22109 CE1 TYR L 152 57.314 59.251 64.460 1.00 73.20 C +ATOM 22110 CE2 TYR L 152 58.906 57.478 64.239 1.00 90.13 C +ATOM 22111 CZ TYR L 152 57.921 58.125 64.962 1.00 84.43 C +ATOM 22112 OH TYR L 152 57.575 57.638 66.208 1.00124.89 O +ATOM 22113 N GLN L 153 57.091 57.608 59.841 1.00127.22 N +ATOM 22114 CA GLN L 153 56.130 56.574 60.190 1.00133.46 C +ATOM 22115 C GLN L 153 56.862 55.283 60.529 1.00120.30 C +ATOM 22116 O GLN L 153 57.976 55.053 60.050 1.00141.72 O +ATOM 22117 CB GLN L 153 55.148 56.350 59.034 1.00144.12 C +ATOM 22118 CG GLN L 153 54.234 57.542 58.716 1.00143.87 C +ATOM 22119 CD GLN L 153 53.381 57.284 57.465 1.00161.95 C +ATOM 22120 OE1 GLN L 153 53.691 56.401 56.649 1.00167.72 O +ATOM 22121 NE2 GLN L 153 52.277 58.011 57.337 1.00171.72 N +ATOM 22122 N LEU L 154 56.249 54.449 61.362 1.00 98.88 N +ATOM 22123 CA LEU L 154 56.811 53.129 61.606 1.00103.68 C +ATOM 22124 C LEU L 154 55.757 52.036 61.770 1.00118.87 C +ATOM 22125 O LEU L 154 54.678 52.251 62.352 1.00115.15 O +ATOM 22126 CB LEU L 154 57.744 53.155 62.811 1.00 83.14 C +ATOM 22127 CG LEU L 154 57.054 53.308 64.159 1.00 92.86 C +ATOM 22128 CD1 LEU L 154 56.825 51.969 64.827 1.00 87.30 C +ATOM 22129 CD2 LEU L 154 57.887 54.214 65.049 1.00135.60 C +ATOM 22130 N ASP L 155 56.146 50.837 61.328 1.00124.73 N +ATOM 22131 CA ASP L 155 55.266 49.668 61.200 1.00 98.18 C +ATOM 22132 C ASP L 155 55.829 48.534 62.056 1.00 88.89 C +ATOM 22133 O ASP L 155 57.004 48.544 62.409 1.00 94.36 O +ATOM 22134 CB ASP L 155 55.200 49.228 59.735 1.00 93.99 C +ATOM 22135 CG ASP L 155 54.971 50.396 58.789 1.00113.82 C +ATOM 22136 OD1 ASP L 155 55.952 51.118 58.475 1.00142.86 O +ATOM 22137 OD2 ASP L 155 53.823 50.581 58.341 1.00123.24 O +ATOM 22138 N GLN L 156 55.000 47.550 62.379 1.00 78.34 N +ATOM 22139 CA GLN L 156 55.462 46.398 63.158 1.00 76.78 C +ATOM 22140 C GLN L 156 55.451 45.095 62.320 1.00 70.09 C +ATOM 22141 O GLN L 156 54.647 44.943 61.405 1.00 74.09 O +ATOM 22142 CB GLN L 156 54.612 46.279 64.428 1.00 79.09 C +ATOM 22143 CG GLN L 156 55.169 45.326 65.470 1.00 97.37 C +ATOM 22144 CD GLN L 156 54.672 45.631 66.883 1.00103.77 C +ATOM 22145 OE1 GLN L 156 53.753 46.426 67.065 1.00122.32 O +ATOM 22146 NE2 GLN L 156 55.217 44.922 67.871 1.00 78.50 N +ATOM 22147 N ILE L 157 56.303 44.150 62.682 1.00 56.23 N +ATOM 22148 CA ILE L 157 56.252 42.811 62.121 1.00 49.78 C +ATOM 22149 C ILE L 157 56.697 41.769 63.187 1.00 54.35 C +ATOM 22150 O ILE L 157 57.528 42.058 64.044 1.00 58.17 O +ATOM 22151 CB ILE L 157 57.170 42.757 60.920 1.00 48.81 C +ATOM 22152 CG1 ILE L 157 56.746 41.633 59.986 1.00 91.09 C +ATOM 22153 CG2 ILE L 157 58.594 42.544 61.354 1.00 47.64 C +ATOM 22154 CD1 ILE L 157 57.484 41.616 58.661 1.00109.64 C +ATOM 22155 N ALA L 158 56.012 40.634 63.260 1.00 53.26 N +ATOM 22156 CA ALA L 158 56.320 39.677 64.304 1.00 44.09 C +ATOM 22157 C ALA L 158 56.386 38.307 63.697 1.00 36.34 C +ATOM 22158 O ALA L 158 55.746 37.998 62.689 1.00 23.82 O +ATOM 22159 CB ALA L 158 55.282 39.716 65.425 1.00 54.49 C +ATOM 22160 N VAL L 159 57.170 37.475 64.332 1.00 35.53 N +ATOM 22161 CA VAL L 159 57.440 36.154 63.804 1.00 41.08 C +ATOM 22162 C VAL L 159 57.438 35.135 64.948 1.00 45.14 C +ATOM 22163 O VAL L 159 58.117 35.309 65.966 1.00 55.79 O +ATOM 22164 CB VAL L 159 58.802 36.134 63.053 1.00 42.15 C +ATOM 22165 CG1 VAL L 159 59.352 34.728 62.939 1.00 47.53 C +ATOM 22166 CG2 VAL L 159 58.670 36.736 61.692 1.00 36.78 C +ATOM 22167 N ASN L 160 56.682 34.081 64.764 1.00 46.17 N +ATOM 22168 CA ASN L 160 56.784 32.934 65.608 1.00 63.79 C +ATOM 22169 C ASN L 160 57.753 31.923 64.945 1.00 63.62 C +ATOM 22170 O ASN L 160 57.604 31.579 63.772 1.00 64.15 O +ATOM 22171 CB ASN L 160 55.384 32.322 65.783 1.00 83.53 C +ATOM 22172 CG ASN L 160 55.382 31.047 66.655 1.00107.49 C +ATOM 22173 OD1 ASN L 160 56.117 30.097 66.386 1.00 84.27 O +ATOM 22174 ND2 ASN L 160 54.420 30.958 67.564 1.00122.39 N +ATOM 22175 N LEU L 161 58.693 31.404 65.722 1.00 51.71 N +ATOM 22176 CA LEU L 161 59.344 30.154 65.391 1.00 40.28 C +ATOM 22177 C LEU L 161 59.149 29.170 66.518 1.00 42.29 C +ATOM 22178 O LEU L 161 59.137 29.527 67.703 1.00 72.67 O +ATOM 22179 CB LEU L 161 60.809 30.415 65.170 1.00 44.90 C +ATOM 22180 CG LEU L 161 61.132 31.316 63.985 1.00 53.26 C +ATOM 22181 CD1 LEU L 161 62.619 31.665 63.994 1.00 73.01 C +ATOM 22182 CD2 LEU L 161 60.745 30.611 62.691 1.00 52.09 C +ATOM 22183 N ARG L 162 59.143 27.903 66.205 1.00 47.21 N +ATOM 22184 CA ARG L 162 59.000 26.911 67.253 1.00 61.26 C +ATOM 22185 C ARG L 162 59.604 25.562 66.908 1.00 63.19 C +ATOM 22186 O ARG L 162 59.342 24.987 65.826 1.00114.04 O +ATOM 22187 CB ARG L 162 57.526 26.788 67.679 1.00 69.00 C +ATOM 22188 CG ARG L 162 56.530 26.309 66.631 1.00 84.60 C +ATOM 22189 CD ARG L 162 55.237 25.852 67.325 1.00101.85 C +ATOM 22190 NE ARG L 162 54.213 25.182 66.525 1.00 90.05 N +ATOM 22191 CZ ARG L 162 53.312 25.849 65.803 1.00 90.46 C +ATOM 22192 NH1 ARG L 162 53.443 27.168 65.543 1.00 87.88 N +ATOM 22193 NH2 ARG L 162 52.336 25.173 65.253 1.00 95.77 N +ATOM 22194 N VAL L 163 60.399 25.046 67.839 1.00 52.01 N +ATOM 22195 CA VAL L 163 60.969 23.694 67.713 1.00 61.16 C +ATOM 22196 C VAL L 163 60.012 22.583 68.148 1.00 47.10 C +ATOM 22197 O VAL L 163 59.565 22.568 69.287 1.00 68.86 O +ATOM 22198 CB VAL L 163 62.211 23.531 68.602 1.00 72.58 C +ATOM 22199 CG1 VAL L 163 62.798 22.108 68.438 1.00 68.66 C +ATOM 22200 CG2 VAL L 163 63.218 24.640 68.319 1.00 74.39 C +ATOM 22201 N VAL L 164 59.801 21.623 67.269 1.00 40.74 N +ATOM 22202 CA VAL L 164 58.910 20.497 67.513 1.00 37.09 C +ATOM 22203 C VAL L 164 59.731 19.280 67.510 1.00 36.33 C +ATOM 22204 O VAL L 164 60.524 19.066 66.598 1.00 40.32 O +ATOM 22205 CB VAL L 164 57.833 20.347 66.398 1.00 34.33 C +ATOM 22206 CG1 VAL L 164 56.969 19.159 66.656 1.00 25.16 C +ATOM 22207 CG2 VAL L 164 56.968 21.623 66.352 1.00 47.14 C +ATOM 22208 N ASN L 165 59.479 18.448 68.489 1.00 56.66 N +ATOM 22209 CA ASN L 165 60.142 17.155 68.572 1.00 87.95 C +ATOM 22210 C ASN L 165 59.446 16.084 67.721 1.00 86.00 C +ATOM 22211 O ASN L 165 58.291 15.750 67.961 1.00 61.54 O +ATOM 22212 CB ASN L 165 60.220 16.665 70.015 1.00 88.64 C +ATOM 22213 CG ASN L 165 61.160 15.494 70.169 1.00100.57 C +ATOM 22214 OD1 ASN L 165 61.851 15.109 69.219 1.00131.55 O +ATOM 22215 ND2 ASN L 165 61.082 14.832 71.298 1.00124.06 N +ATOM 22216 N VAL L 166 60.170 15.575 66.719 1.00 94.22 N +ATOM 22217 CA VAL L 166 59.634 14.615 65.760 1.00 84.48 C +ATOM 22218 C VAL L 166 59.186 13.386 66.482 1.00 66.28 C +ATOM 22219 O VAL L 166 58.158 12.829 66.167 1.00 83.80 O +ATOM 22220 CB VAL L 166 60.695 14.240 64.705 1.00101.28 C +ATOM 22221 CG1 VAL L 166 60.433 12.863 64.115 1.00 96.83 C +ATOM 22222 CG2 VAL L 166 60.772 15.321 63.622 1.00104.03 C +ATOM 22223 N SER L 167 59.945 12.994 67.485 1.00 65.61 N +ATOM 22224 CA SER L 167 59.706 11.741 68.158 1.00 82.33 C +ATOM 22225 C SER L 167 58.427 11.752 69.008 1.00 80.12 C +ATOM 22226 O SER L 167 57.994 10.680 69.466 1.00 89.34 O +ATOM 22227 CB SER L 167 60.932 11.376 69.008 1.00 97.28 C +ATOM 22228 OG SER L 167 62.131 11.579 68.266 1.00139.93 O +ATOM 22229 N THR L 168 57.870 12.941 69.282 1.00 64.05 N +ATOM 22230 CA THR L 168 56.714 13.034 70.184 1.00 65.30 C +ATOM 22231 C THR L 168 55.638 13.978 69.725 1.00 70.34 C +ATOM 22232 O THR L 168 54.422 13.774 69.937 1.00 62.48 O +ATOM 22233 CB THR L 168 57.116 13.488 71.597 1.00 69.24 C +ATOM 22234 OG1 THR L 168 57.924 14.657 71.509 1.00 47.11 O +ATOM 22235 CG2 THR L 168 57.894 12.372 72.323 1.00101.29 C +ATOM 22236 N GLY L 169 56.072 15.069 69.143 1.00 77.29 N +ATOM 22237 CA GLY L 169 55.106 16.091 68.766 1.00 95.98 C +ATOM 22238 C GLY L 169 55.092 17.200 69.793 1.00 61.50 C +ATOM 22239 O GLY L 169 54.457 18.214 69.576 1.00 50.29 O +ATOM 22240 N GLU L 170 55.732 16.957 70.929 1.00 51.55 N +ATOM 22241 CA GLU L 170 55.898 17.990 71.937 1.00 51.36 C +ATOM 22242 C GLU L 170 56.570 19.101 71.227 1.00 43.14 C +ATOM 22243 O GLU L 170 57.587 18.927 70.570 1.00 49.04 O +ATOM 22244 CB GLU L 170 56.765 17.516 73.120 1.00 70.49 C +ATOM 22245 CG GLU L 170 56.030 16.638 74.134 1.00 99.80 C +ATOM 22246 CD GLU L 170 56.872 15.500 74.727 1.00133.95 C +ATOM 22247 OE1 GLU L 170 57.965 15.218 74.203 1.00144.81 O +ATOM 22248 OE2 GLU L 170 56.392 14.814 75.659 1.00148.70 O +ATOM 22249 N ILE L 171 56.022 20.283 71.368 1.00 52.99 N +ATOM 22250 CA ILE L 171 56.774 21.475 71.035 1.00 57.73 C +ATOM 22251 C ILE L 171 57.846 21.700 72.098 1.00 59.75 C +ATOM 22252 O ILE L 171 57.549 21.711 73.284 1.00 82.39 O +ATOM 22253 CB ILE L 171 55.854 22.699 70.942 1.00 53.38 C +ATOM 22254 CG1 ILE L 171 54.944 22.565 69.705 1.00 43.17 C +ATOM 22255 CG2 ILE L 171 56.706 23.971 70.908 1.00 47.11 C +ATOM 22256 CD1 ILE L 171 53.780 23.491 69.751 1.00 37.56 C +ATOM 22257 N LEU L 172 59.106 21.785 71.682 1.00 61.88 N +ATOM 22258 CA LEU L 172 60.207 21.893 72.643 1.00 58.16 C +ATOM 22259 C LEU L 172 60.533 23.354 72.977 1.00 54.05 C +ATOM 22260 O LEU L 172 61.320 23.651 73.884 1.00 56.74 O +ATOM 22261 CB LEU L 172 61.447 21.130 72.153 1.00 63.47 C +ATOM 22262 CG LEU L 172 61.307 19.584 72.152 1.00 80.57 C +ATOM 22263 CD1 LEU L 172 62.557 18.748 71.817 1.00 79.32 C +ATOM 22264 CD2 LEU L 172 60.652 19.075 73.425 1.00108.17 C +ATOM 22265 N SER L 173 59.995 24.259 72.170 1.00 60.94 N +ATOM 22266 CA SER L 173 60.295 25.672 72.295 1.00 66.04 C +ATOM 22267 C SER L 173 59.433 26.498 71.355 1.00 60.37 C +ATOM 22268 O SER L 173 59.396 26.257 70.155 1.00 57.96 O +ATOM 22269 CB SER L 173 61.779 25.975 71.986 1.00 81.82 C +ATOM 22270 OG SER L 173 61.979 27.377 71.830 1.00105.90 O +ATOM 22271 N SER L 174 58.805 27.530 71.897 1.00 70.42 N +ATOM 22272 CA SER L 174 58.152 28.558 71.083 1.00 80.08 C +ATOM 22273 C SER L 174 58.724 29.923 71.430 1.00 76.47 C +ATOM 22274 O SER L 174 58.932 30.230 72.589 1.00 70.56 O +ATOM 22275 CB SER L 174 56.628 28.570 71.307 1.00 88.76 C +ATOM 22276 OG SER L 174 55.940 29.373 70.350 1.00 62.70 O +ATOM 22277 N VAL L 175 58.976 30.733 70.401 1.00 87.76 N +ATOM 22278 CA VAL L 175 59.518 32.097 70.579 1.00 73.74 C +ATOM 22279 C VAL L 175 58.846 33.103 69.661 1.00 55.85 C +ATOM 22280 O VAL L 175 58.470 32.755 68.517 1.00 73.30 O +ATOM 22281 CB VAL L 175 61.033 32.127 70.324 1.00 89.11 C +ATOM 22282 CG1 VAL L 175 61.776 31.248 71.321 1.00 93.66 C +ATOM 22283 CG2 VAL L 175 61.372 31.653 68.915 1.00 99.12 C +ATOM 22284 N ASN L 176 58.683 34.315 70.154 1.00 49.48 N +ATOM 22285 CA ASN L 176 57.853 35.330 69.458 1.00 57.80 C +ATOM 22286 C ASN L 176 58.559 36.670 69.265 1.00 59.94 C +ATOM 22287 O ASN L 176 58.574 37.480 70.174 1.00 62.20 O +ATOM 22288 CB ASN L 176 56.574 35.580 70.265 1.00 61.09 C +ATOM 22289 CG ASN L 176 55.353 34.850 69.704 1.00 81.06 C +ATOM 22290 OD1 ASN L 176 54.177 35.077 70.142 1.00125.19 O +ATOM 22291 ND2 ASN L 176 55.615 33.915 68.797 1.00 70.95 N +ATOM 22292 N THR L 177 59.234 36.850 68.134 1.00 63.96 N +ATOM 22293 CA THR L 177 60.094 38.016 67.938 1.00 59.59 C +ATOM 22294 C THR L 177 59.363 39.057 67.151 1.00 65.40 C +ATOM 22295 O THR L 177 58.360 38.776 66.499 1.00 57.29 O +ATOM 22296 CB THR L 177 61.397 37.681 67.187 1.00 72.16 C +ATOM 22297 OG1 THR L 177 61.104 37.316 65.835 1.00 55.69 O +ATOM 22298 CG2 THR L 177 62.162 36.512 67.860 1.00 81.64 C +ATOM 22299 N SER L 178 59.825 40.284 67.293 1.00 82.04 N +ATOM 22300 CA SER L 178 59.134 41.424 66.707 1.00 85.16 C +ATOM 22301 C SER L 178 60.133 42.468 66.281 1.00 79.51 C +ATOM 22302 O SER L 178 61.232 42.592 66.843 1.00 95.37 O +ATOM 22303 CB SER L 178 58.149 42.048 67.696 1.00 91.63 C +ATOM 22304 OG SER L 178 57.721 43.335 67.266 1.00 87.08 O +ATOM 22305 N LYS L 179 59.744 43.250 65.293 1.00 68.59 N +ATOM 22306 CA LYS L 179 60.672 44.199 64.722 1.00 82.06 C +ATOM 22307 C LYS L 179 59.908 45.367 64.094 1.00 86.85 C +ATOM 22308 O LYS L 179 58.823 45.200 63.532 1.00 64.92 O +ATOM 22309 CB LYS L 179 61.559 43.485 63.695 1.00 81.52 C +ATOM 22310 CG LYS L 179 62.990 43.975 63.637 1.00 87.91 C +ATOM 22311 CD LYS L 179 63.136 45.039 62.566 1.00 99.70 C +ATOM 22312 CE LYS L 179 64.515 45.655 62.623 1.00109.38 C +ATOM 22313 NZ LYS L 179 64.593 46.883 61.800 1.00128.23 N +ATOM 22314 N THR L 180 60.505 46.549 64.179 1.00 90.78 N +ATOM 22315 CA THR L 180 59.857 47.750 63.706 1.00 84.59 C +ATOM 22316 C THR L 180 60.503 48.235 62.403 1.00 84.71 C +ATOM 22317 O THR L 180 61.735 48.333 62.285 1.00 99.87 O +ATOM 22318 CB THR L 180 59.862 48.849 64.781 1.00 81.20 C +ATOM 22319 OG1 THR L 180 59.767 50.132 64.157 1.00 79.12 O +ATOM 22320 CG2 THR L 180 61.138 48.790 65.625 1.00 88.85 C +ATOM 22321 N ILE L 181 59.660 48.564 61.436 1.00 82.60 N +ATOM 22322 CA ILE L 181 60.124 49.102 60.163 1.00 91.86 C +ATOM 22323 C ILE L 181 60.002 50.642 60.128 1.00 95.28 C +ATOM 22324 O ILE L 181 58.892 51.193 60.216 1.00104.40 O +ATOM 22325 CB ILE L 181 59.331 48.481 58.988 1.00113.84 C +ATOM 22326 CG1 ILE L 181 59.349 46.957 59.079 1.00105.37 C +ATOM 22327 CG2 ILE L 181 59.893 48.911 57.635 1.00135.83 C +ATOM 22328 CD1 ILE L 181 57.976 46.342 59.221 1.00102.42 C +ATOM 22329 N LEU L 182 61.140 51.321 59.965 1.00 81.78 N +ATOM 22330 CA LEU L 182 61.201 52.779 59.993 1.00 82.00 C +ATOM 22331 C LEU L 182 61.111 53.418 58.619 1.00 94.06 C +ATOM 22332 O LEU L 182 61.746 52.974 57.658 1.00 78.35 O +ATOM 22333 CB LEU L 182 62.497 53.232 60.650 1.00 87.54 C +ATOM 22334 CG LEU L 182 62.711 54.749 60.730 1.00 90.17 C +ATOM 22335 CD1 LEU L 182 61.649 55.465 61.563 1.00 78.91 C +ATOM 22336 CD2 LEU L 182 64.104 55.001 61.291 1.00105.66 C +ATOM 22337 N SER L 183 60.361 54.517 58.551 1.00129.78 N +ATOM 22338 CA SER L 183 60.282 55.342 57.345 1.00142.05 C +ATOM 22339 C SER L 183 60.318 56.838 57.718 1.00124.47 C +ATOM 22340 O SER L 183 59.705 57.250 58.698 1.00 96.51 O +ATOM 22341 CB SER L 183 59.000 55.012 56.570 1.00129.91 C +ATOM 22342 OG SER L 183 58.713 53.618 56.636 1.00140.83 O +ATOM 22343 N TYR L 184 61.027 57.637 56.927 1.00110.23 N +ATOM 22344 CA TYR L 184 61.034 59.078 57.132 1.00102.92 C +ATOM 22345 C TYR L 184 61.249 59.890 55.850 1.00135.90 C +ATOM 22346 O TYR L 184 61.828 59.421 54.861 1.00130.89 O +ATOM 22347 CB TYR L 184 62.062 59.465 58.184 1.00 93.38 C +ATOM 22348 CG TYR L 184 63.469 59.043 57.846 1.00 92.90 C +ATOM 22349 CD1 TYR L 184 64.310 59.844 57.085 1.00 79.68 C +ATOM 22350 CD2 TYR L 184 63.963 57.835 58.296 1.00124.37 C +ATOM 22351 CE1 TYR L 184 65.597 59.442 56.767 1.00 86.30 C +ATOM 22352 CE2 TYR L 184 65.262 57.425 57.989 1.00139.27 C +ATOM 22353 CZ TYR L 184 66.078 58.232 57.222 1.00102.56 C +ATOM 22354 OH TYR L 184 67.379 57.821 56.957 1.00 67.39 O +ATOM 22355 N GLU L 185 60.757 61.127 55.895 1.00158.38 N +ATOM 22356 CA GLU L 185 60.806 62.061 54.772 1.00171.00 C +ATOM 22357 C GLU L 185 61.298 63.424 55.225 1.00165.72 C +ATOM 22358 O GLU L 185 60.605 64.125 55.955 1.00165.95 O +ATOM 22359 CB GLU L 185 59.439 62.250 54.100 1.00171.48 C +ATOM 22360 CG GLU L 185 58.614 60.997 53.909 1.00183.13 C +ATOM 22361 CD GLU L 185 57.387 61.269 53.054 1.00184.12 C +ATOM 22362 OE1 GLU L 185 57.178 62.439 52.663 1.00164.23 O +ATOM 22363 OE2 GLU L 185 56.651 60.310 52.751 1.00208.57 O +ATOM 22364 N VAL L 186 62.484 63.795 54.759 1.00154.04 N +ATOM 22365 CA VAL L 186 63.063 65.097 55.036 1.00134.62 C +ATOM 22366 C VAL L 186 62.917 65.993 53.813 1.00137.47 C +ATOM 22367 O VAL L 186 63.085 65.547 52.679 1.00149.62 O +ATOM 22368 CB VAL L 186 64.549 64.966 55.396 1.00129.80 C +ATOM 22369 CG1 VAL L 186 65.092 66.300 55.879 1.00148.12 C +ATOM 22370 CG2 VAL L 186 64.745 63.896 56.463 1.00141.80 C +ATOM 22371 N GLN L 187 62.577 67.254 54.048 1.00148.42 N +ATOM 22372 CA GLN L 187 62.321 68.184 52.959 1.00161.35 C +ATOM 22373 C GLN L 187 62.721 69.594 53.352 1.00178.98 C +ATOM 22374 O GLN L 187 62.405 70.044 54.451 1.00167.12 O +ATOM 22375 CB GLN L 187 60.827 68.170 52.598 1.00155.21 C +ATOM 22376 CG GLN L 187 60.407 67.097 51.613 1.00155.25 C +ATOM 22377 CD GLN L 187 58.920 66.804 51.688 1.00155.59 C +ATOM 22378 OE1 GLN L 187 58.107 67.718 51.858 1.00111.77 O +ATOM 22379 NE2 GLN L 187 58.554 65.522 51.575 1.00162.51 N +ATOM 22380 N ALA L 188 63.355 70.299 52.420 1.00185.34 N +ATOM 22381 CA ALA L 188 63.707 71.697 52.638 1.00152.07 C +ATOM 22382 C ALA L 188 63.537 72.502 51.354 1.00175.39 C +ATOM 22383 O ALA L 188 63.806 72.009 50.259 1.00208.22 O +ATOM 22384 CB ALA L 188 65.129 71.795 53.140 1.00123.58 C +ATOM 22385 N GLY L 189 63.023 73.716 51.480 1.00181.43 N +ATOM 22386 CA GLY L 189 62.778 74.568 50.324 1.00202.27 C +ATOM 22387 C GLY L 189 63.031 76.035 50.617 1.00203.54 C +ATOM 22388 O GLY L 189 62.634 76.534 51.666 1.00186.90 O +ATOM 22389 N VAL L 190 63.662 76.724 49.670 1.00193.07 N +ATOM 22390 CA VAL L 190 63.879 78.159 49.766 1.00165.55 C +ATOM 22391 C VAL L 190 63.088 78.895 48.667 1.00169.76 C +ATOM 22392 O VAL L 190 63.069 78.478 47.507 1.00143.97 O +ATOM 22393 CB VAL L 190 65.374 78.494 49.650 1.00142.75 C +ATOM 22394 CG1 VAL L 190 65.615 79.947 50.026 1.00141.32 C +ATOM 22395 CG2 VAL L 190 66.200 77.560 50.522 1.00129.24 C +ATOM 22396 N PHE L 191 62.423 79.988 49.039 1.00176.28 N +ATOM 22397 CA PHE L 191 61.489 80.676 48.137 1.00166.44 C +ATOM 22398 C PHE L 191 61.730 82.187 48.161 1.00151.50 C +ATOM 22399 O PHE L 191 61.815 82.776 49.251 1.00200.13 O +ATOM 22400 CB PHE L 191 60.038 80.351 48.543 1.00172.42 C +ATOM 22401 CG PHE L 191 59.034 80.562 47.439 1.00192.23 C +ATOM 22402 CD1 PHE L 191 58.699 81.841 47.021 1.00179.81 C +ATOM 22403 CD2 PHE L 191 58.429 79.480 46.814 1.00207.52 C +ATOM 22404 CE1 PHE L 191 57.775 82.039 46.008 1.00158.66 C +ATOM 22405 CE2 PHE L 191 57.517 79.671 45.788 1.00190.51 C +ATOM 22406 CZ PHE L 191 57.181 80.954 45.391 1.00157.87 C +ATOM 22407 N LEU L 200 63.010 83.253 42.670 1.00148.99 N +ATOM 22408 CA LEU L 200 63.860 82.179 43.159 1.00153.15 C +ATOM 22409 C LEU L 200 63.057 81.171 43.970 1.00199.12 C +ATOM 22410 O LEU L 200 62.589 81.475 45.076 1.00185.20 O +ATOM 22411 CB LEU L 200 65.000 82.720 44.030 1.00148.27 C +ATOM 22412 CG LEU L 200 65.833 81.635 44.737 1.00151.82 C +ATOM 22413 CD1 LEU L 200 67.141 81.392 43.992 1.00139.28 C +ATOM 22414 CD2 LEU L 200 66.082 81.946 46.214 1.00144.02 C +ATOM 22415 N GLU L 201 62.956 79.953 43.439 1.00232.28 N +ATOM 22416 CA GLU L 201 62.595 78.785 44.241 1.00229.82 C +ATOM 22417 C GLU L 201 63.695 77.729 44.181 1.00213.00 C +ATOM 22418 O GLU L 201 64.388 77.605 43.175 1.00214.35 O +ATOM 22419 CB GLU L 201 61.282 78.180 43.754 1.00208.35 C +ATOM 22420 CG GLU L 201 60.619 77.296 44.796 1.00214.79 C +ATOM 22421 CD GLU L 201 59.311 76.691 44.318 1.00218.73 C +ATOM 22422 OE1 GLU L 201 58.442 77.445 43.826 1.00219.03 O +ATOM 22423 OE2 GLU L 201 59.135 75.461 44.470 1.00218.96 O +ATOM 22424 N GLY L 202 63.869 76.993 45.275 1.00194.09 N +ATOM 22425 CA GLY L 202 64.791 75.864 45.308 1.00212.65 C +ATOM 22426 C GLY L 202 64.373 74.841 46.347 1.00234.10 C +ATOM 22427 O GLY L 202 64.180 75.179 47.515 1.00265.15 O +ATOM 22428 N GLU L 203 64.220 73.587 45.925 1.00223.76 N +ATOM 22429 CA GLU L 203 63.742 72.534 46.819 1.00174.59 C +ATOM 22430 C GLU L 203 64.613 71.280 46.801 1.00184.52 C +ATOM 22431 O GLU L 203 65.012 70.790 45.740 1.00188.00 O +ATOM 22432 CB GLU L 203 62.304 72.160 46.475 1.00147.28 C +ATOM 22433 CG GLU L 203 61.312 73.287 46.747 1.00164.17 C +ATOM 22434 CD GLU L 203 59.852 72.907 46.509 1.00190.19 C +ATOM 22435 OE1 GLU L 203 59.598 71.805 45.980 1.00181.46 O +ATOM 22436 OE2 GLU L 203 58.961 73.738 46.813 1.00210.44 O +ATOM 22437 N VAL L 204 64.884 70.764 47.995 1.00179.04 N +ATOM 22438 CA VAL L 204 65.539 69.471 48.170 1.00145.04 C +ATOM 22439 C VAL L 204 64.633 68.571 49.011 1.00142.81 C +ATOM 22440 O VAL L 204 64.043 69.009 50.004 1.00116.66 O +ATOM 22441 CB VAL L 204 66.914 69.635 48.845 1.00115.61 C +ATOM 22442 CG1 VAL L 204 67.443 68.306 49.377 1.00117.05 C +ATOM 22443 CG2 VAL L 204 67.893 70.253 47.864 1.00104.35 C +ATOM 22444 N GLY L 205 64.511 67.319 48.587 1.00142.03 N +ATOM 22445 CA GLY L 205 63.743 66.332 49.326 1.00141.38 C +ATOM 22446 C GLY L 205 64.465 64.994 49.389 1.00151.53 C +ATOM 22447 O GLY L 205 65.217 64.634 48.478 1.00183.06 O +ATOM 22448 N TYR L 206 64.243 64.259 50.474 1.00133.43 N +ATOM 22449 CA TYR L 206 64.791 62.911 50.626 1.00104.12 C +ATOM 22450 C TYR L 206 63.857 62.043 51.450 1.00118.06 C +ATOM 22451 O TYR L 206 63.235 62.523 52.387 1.00122.48 O +ATOM 22452 CB TYR L 206 66.139 62.956 51.321 1.00 97.23 C +ATOM 22453 CG TYR L 206 66.720 61.587 51.576 1.00 97.80 C +ATOM 22454 CD1 TYR L 206 67.312 60.850 50.548 1.00108.46 C +ATOM 22455 CD2 TYR L 206 66.674 61.020 52.838 1.00 97.62 C +ATOM 22456 CE1 TYR L 206 67.848 59.590 50.780 1.00103.85 C +ATOM 22457 CE2 TYR L 206 67.221 59.765 53.082 1.00101.35 C +ATOM 22458 CZ TYR L 206 67.809 59.053 52.058 1.00 94.15 C +ATOM 22459 OH TYR L 206 68.405 57.834 52.329 1.00 72.86 O +ATOM 22460 N THR L 207 63.711 60.779 51.062 1.00144.94 N +ATOM 22461 CA THR L 207 62.832 59.851 51.782 1.00135.77 C +ATOM 22462 C THR L 207 63.511 58.499 51.919 1.00133.97 C +ATOM 22463 O THR L 207 64.122 57.992 50.959 1.00137.00 O +ATOM 22464 CB THR L 207 61.469 59.660 51.075 1.00121.29 C +ATOM 22465 OG1 THR L 207 61.674 59.109 49.771 1.00118.85 O +ATOM 22466 CG2 THR L 207 60.742 60.983 50.925 1.00138.63 C +ATOM 22467 N SER L 208 63.401 57.907 53.105 1.00114.07 N +ATOM 22468 CA SER L 208 64.009 56.593 53.334 1.00127.83 C +ATOM 22469 C SER L 208 63.076 55.629 54.039 1.00118.09 C +ATOM 22470 O SER L 208 62.515 55.953 55.084 1.00 93.16 O +ATOM 22471 CB SER L 208 65.301 56.712 54.137 1.00148.20 C +ATOM 22472 OG SER L 208 65.795 55.421 54.474 1.00155.65 O +ATOM 22473 N ASN L 209 62.895 54.458 53.421 1.00126.00 N +ATOM 22474 CA ASN L 209 62.127 53.358 53.998 1.00100.14 C +ATOM 22475 C ASN L 209 63.066 52.225 54.312 1.00 90.41 C +ATOM 22476 O ASN L 209 63.901 51.860 53.490 1.00 99.96 O +ATOM 22477 CB ASN L 209 61.065 52.845 53.022 1.00 84.08 C +ATOM 22478 CG ASN L 209 59.936 53.820 52.825 1.00 93.58 C +ATOM 22479 OD1 ASN L 209 59.014 53.907 53.634 1.00101.09 O +ATOM 22480 ND2 ASN L 209 59.997 54.565 51.733 1.00 90.01 N +ATOM 22481 N GLU L 210 62.891 51.637 55.477 1.00 75.83 N +ATOM 22482 CA GLU L 210 63.513 50.364 55.744 1.00 81.16 C +ATOM 22483 C GLU L 210 62.891 49.307 54.834 1.00 86.81 C +ATOM 22484 O GLU L 210 61.681 49.313 54.581 1.00120.78 O +ATOM 22485 CB GLU L 210 63.304 49.976 57.210 1.00101.57 C +ATOM 22486 CG GLU L 210 64.540 49.432 57.912 1.00121.95 C +ATOM 22487 CD GLU L 210 64.423 49.478 59.437 1.00110.13 C +ATOM 22488 OE1 GLU L 210 63.675 50.322 59.990 1.00 75.59 O +ATOM 22489 OE2 GLU L 210 65.100 48.658 60.081 1.00106.32 O +ATOM 22490 N PRO L 211 63.708 48.383 54.337 1.00 70.57 N +ATOM 22491 CA PRO L 211 63.133 47.250 53.640 1.00 73.83 C +ATOM 22492 C PRO L 211 62.434 46.268 54.576 1.00 74.92 C +ATOM 22493 O PRO L 211 63.052 45.788 55.538 1.00 66.74 O +ATOM 22494 CB PRO L 211 64.353 46.596 52.969 1.00 70.98 C +ATOM 22495 CG PRO L 211 65.411 47.636 52.975 1.00 68.51 C +ATOM 22496 CD PRO L 211 65.165 48.395 54.237 1.00 69.51 C +ATOM 22497 N VAL L 212 61.154 45.989 54.296 1.00 76.58 N +ATOM 22498 CA VAL L 212 60.378 45.029 55.078 1.00 88.17 C +ATOM 22499 C VAL L 212 60.988 43.631 54.951 1.00100.90 C +ATOM 22500 O VAL L 212 61.142 42.903 55.944 1.00148.03 O +ATOM 22501 CB VAL L 212 58.928 44.947 54.595 1.00 97.71 C +ATOM 22502 CG1 VAL L 212 58.110 44.053 55.521 1.00102.50 C +ATOM 22503 CG2 VAL L 212 58.298 46.338 54.502 1.00109.57 C +ATOM 22504 N MET L 213 61.349 43.292 53.722 1.00 98.58 N +ATOM 22505 CA MET L 213 62.298 42.225 53.394 1.00109.51 C +ATOM 22506 C MET L 213 63.439 41.988 54.411 1.00104.04 C +ATOM 22507 O MET L 213 63.627 40.876 54.945 1.00 90.36 O +ATOM 22508 CB MET L 213 62.906 42.640 52.059 1.00134.06 C +ATOM 22509 CG MET L 213 63.821 41.664 51.375 1.00144.45 C +ATOM 22510 SD MET L 213 64.348 42.458 49.838 1.00136.67 S +ATOM 22511 CE MET L 213 66.050 42.702 50.281 1.00110.80 C +ATOM 22512 N LEU L 214 64.122 43.074 54.759 1.00102.62 N +ATOM 22513 CA LEU L 214 65.345 43.007 55.547 1.00120.93 C +ATOM 22514 C LEU L 214 65.034 42.936 57.050 1.00108.49 C +ATOM 22515 O LEU L 214 65.771 42.320 57.826 1.00 95.12 O +ATOM 22516 CB LEU L 214 66.214 44.232 55.252 1.00134.25 C +ATOM 22517 CG LEU L 214 67.723 44.033 55.012 1.00146.96 C +ATOM 22518 CD1 LEU L 214 68.024 43.093 53.828 1.00135.26 C +ATOM 22519 CD2 LEU L 214 68.373 45.402 54.811 1.00136.90 C +ATOM 22520 N CYS L 215 63.903 43.511 57.441 1.00115.12 N +ATOM 22521 CA CYS L 215 63.401 43.421 58.826 1.00122.36 C +ATOM 22522 C CYS L 215 62.852 42.032 59.182 1.00 99.54 C +ATOM 22523 O CYS L 215 63.141 41.482 60.261 1.00101.23 O +ATOM 22524 CB CYS L 215 62.263 44.408 59.045 1.00118.15 C +ATOM 22525 SG CYS L 215 62.761 46.121 58.879 1.00 82.02 S +ATOM 22526 N LEU L 216 62.091 41.471 58.254 1.00 63.73 N +ATOM 22527 CA LEU L 216 61.739 40.082 58.348 1.00 66.63 C +ATOM 22528 C LEU L 216 62.992 39.212 58.578 1.00 73.31 C +ATOM 22529 O LEU L 216 63.010 38.348 59.474 1.00 96.56 O +ATOM 22530 CB LEU L 216 60.992 39.613 57.082 1.00 64.72 C +ATOM 22531 CG LEU L 216 60.542 38.154 57.072 1.00 54.62 C +ATOM 22532 CD1 LEU L 216 59.654 37.824 58.253 1.00 74.43 C +ATOM 22533 CD2 LEU L 216 59.820 37.835 55.807 1.00 51.19 C +ATOM 22534 N MET L 217 64.018 39.392 57.737 1.00 71.15 N +ATOM 22535 CA MET L 217 65.198 38.538 57.784 1.00 80.03 C +ATOM 22536 C MET L 217 65.876 38.674 59.145 1.00 74.43 C +ATOM 22537 O MET L 217 66.200 37.678 59.798 1.00 73.48 O +ATOM 22538 CB MET L 217 66.166 38.868 56.651 1.00 89.18 C +ATOM 22539 CG MET L 217 66.764 37.630 55.988 1.00126.07 C +ATOM 22540 SD MET L 217 67.922 36.735 57.061 1.00174.55 S +ATOM 22541 CE MET L 217 68.231 35.219 56.143 1.00135.08 C +ATOM 22542 N SER L 218 66.012 39.908 59.598 1.00 81.85 N +ATOM 22543 CA SER L 218 66.630 40.203 60.892 1.00 88.85 C +ATOM 22544 C SER L 218 65.903 39.487 62.007 1.00 68.97 C +ATOM 22545 O SER L 218 66.520 38.847 62.859 1.00 83.15 O +ATOM 22546 CB SER L 218 66.615 41.721 61.141 1.00110.77 C +ATOM 22547 OG SER L 218 67.386 42.081 62.263 1.00 88.77 O +ATOM 22548 N ALA L 219 64.589 39.637 62.025 1.00 63.82 N +ATOM 22549 CA ALA L 219 63.785 39.095 63.111 1.00 87.87 C +ATOM 22550 C ALA L 219 63.850 37.559 63.163 1.00 72.76 C +ATOM 22551 O ALA L 219 63.822 36.948 64.233 1.00 49.78 O +ATOM 22552 CB ALA L 219 62.342 39.577 62.966 1.00121.41 C +ATOM 22553 N ILE L 220 63.949 36.940 61.996 1.00 82.81 N +ATOM 22554 CA ILE L 220 64.041 35.483 61.923 1.00 87.28 C +ATOM 22555 C ILE L 220 65.381 34.991 62.476 1.00 89.01 C +ATOM 22556 O ILE L 220 65.426 34.029 63.238 1.00 76.90 O +ATOM 22557 CB ILE L 220 63.862 34.977 60.475 1.00 84.89 C +ATOM 22558 CG1 ILE L 220 62.397 35.180 60.029 1.00 78.29 C +ATOM 22559 CG2 ILE L 220 64.274 33.511 60.366 1.00 84.27 C +ATOM 22560 CD1 ILE L 220 62.184 35.087 58.534 1.00 74.63 C +ATOM 22561 N GLU L 221 66.458 35.695 62.148 1.00 99.73 N +ATOM 22562 CA GLU L 221 67.768 35.419 62.751 1.00 96.81 C +ATOM 22563 C GLU L 221 67.720 35.477 64.297 1.00 71.16 C +ATOM 22564 O GLU L 221 68.122 34.534 64.972 1.00 47.96 O +ATOM 22565 CB GLU L 221 68.810 36.420 62.225 1.00123.37 C +ATOM 22566 CG GLU L 221 69.205 36.183 60.777 1.00138.79 C +ATOM 22567 CD GLU L 221 69.908 37.374 60.133 1.00143.23 C +ATOM 22568 OE1 GLU L 221 69.544 38.548 60.417 1.00100.00 O +ATOM 22569 OE2 GLU L 221 70.801 37.106 59.296 1.00131.80 O +ATOM 22570 N THR L 222 67.216 36.598 64.822 1.00 53.34 N +ATOM 22571 CA THR L 222 67.006 36.808 66.247 1.00 42.39 C +ATOM 22572 C THR L 222 66.240 35.659 66.883 1.00 41.21 C +ATOM 22573 O THR L 222 66.667 35.118 67.903 1.00 44.31 O +ATOM 22574 CB THR L 222 66.199 38.096 66.480 1.00 46.97 C +ATOM 22575 OG1 THR L 222 67.014 39.250 66.179 1.00 47.36 O +ATOM 22576 CG2 THR L 222 65.656 38.161 67.916 1.00 51.38 C +ATOM 22577 N GLY L 223 65.117 35.292 66.277 1.00 47.52 N +ATOM 22578 CA GLY L 223 64.382 34.113 66.684 1.00 65.86 C +ATOM 22579 C GLY L 223 65.225 32.824 66.759 1.00 88.48 C +ATOM 22580 O GLY L 223 65.075 32.020 67.696 1.00 79.97 O +ATOM 22581 N VAL L 224 66.089 32.611 65.769 1.00 87.71 N +ATOM 22582 CA VAL L 224 66.912 31.417 65.741 1.00 82.64 C +ATOM 22583 C VAL L 224 67.871 31.417 66.931 1.00 77.42 C +ATOM 22584 O VAL L 224 68.064 30.393 67.589 1.00 93.22 O +ATOM 22585 CB VAL L 224 67.726 31.315 64.451 1.00 87.58 C +ATOM 22586 CG1 VAL L 224 68.726 30.167 64.538 1.00 87.97 C +ATOM 22587 CG2 VAL L 224 66.807 31.134 63.259 1.00 80.52 C +ATOM 22588 N ILE L 225 68.439 32.571 67.236 1.00 70.80 N +ATOM 22589 CA ILE L 225 69.318 32.682 68.398 1.00 81.98 C +ATOM 22590 C ILE L 225 68.554 32.296 69.666 1.00 79.61 C +ATOM 22591 O ILE L 225 69.044 31.486 70.448 1.00 60.32 O +ATOM 22592 CB ILE L 225 69.936 34.100 68.537 1.00 85.14 C +ATOM 22593 CG1 ILE L 225 70.910 34.356 67.384 1.00 92.38 C +ATOM 22594 CG2 ILE L 225 70.671 34.248 69.853 1.00 68.07 C +ATOM 22595 CD1 ILE L 225 71.227 35.823 67.170 1.00109.96 C +ATOM 22596 N PHE L 226 67.387 32.920 69.889 1.00 83.81 N +ATOM 22597 CA PHE L 226 66.585 32.671 71.107 1.00 75.10 C +ATOM 22598 C PHE L 226 66.252 31.194 71.210 1.00 69.50 C +ATOM 22599 O PHE L 226 66.148 30.654 72.306 1.00 73.26 O +ATOM 22600 CB PHE L 226 65.292 33.506 71.121 1.00 69.12 C +ATOM 22601 CG PHE L 226 65.473 34.931 71.569 1.00 79.02 C +ATOM 22602 CD1 PHE L 226 66.031 35.221 72.808 1.00 95.54 C +ATOM 22603 CD2 PHE L 226 65.075 35.993 70.760 1.00 78.04 C +ATOM 22604 CE1 PHE L 226 66.212 36.539 73.222 1.00 92.46 C +ATOM 22605 CE2 PHE L 226 65.249 37.305 71.180 1.00 79.23 C +ATOM 22606 CZ PHE L 226 65.814 37.576 72.411 1.00 77.23 C +ATOM 22607 N LEU L 227 66.081 30.547 70.064 1.00 76.79 N +ATOM 22608 CA LEU L 227 65.783 29.111 70.033 1.00 81.28 C +ATOM 22609 C LEU L 227 66.981 28.302 70.492 1.00 64.65 C +ATOM 22610 O LEU L 227 66.835 27.387 71.268 1.00 65.03 O +ATOM 22611 CB LEU L 227 65.354 28.712 68.624 1.00 82.14 C +ATOM 22612 CG LEU L 227 63.922 29.084 68.204 1.00 75.82 C +ATOM 22613 CD1 LEU L 227 63.631 28.947 66.726 1.00 82.62 C +ATOM 22614 CD2 LEU L 227 62.912 28.269 68.989 1.00 88.11 C +ATOM 22615 N ILE L 228 68.163 28.675 70.030 1.00 63.02 N +ATOM 22616 CA ILE L 228 69.358 27.945 70.377 1.00 71.73 C +ATOM 22617 C ILE L 228 69.584 28.106 71.859 1.00 69.85 C +ATOM 22618 O ILE L 228 69.934 27.156 72.569 1.00 59.06 O +ATOM 22619 CB ILE L 228 70.600 28.439 69.589 1.00 99.33 C +ATOM 22620 CG1 ILE L 228 70.442 28.150 68.094 1.00103.89 C +ATOM 22621 CG2 ILE L 228 71.866 27.739 70.076 1.00113.49 C +ATOM 22622 CD1 ILE L 228 71.413 28.895 67.204 1.00109.20 C +ATOM 22623 N ASN L 229 69.533 29.349 72.315 1.00 79.29 N +ATOM 22624 CA ASN L 229 69.841 29.654 73.721 1.00 86.67 C +ATOM 22625 C ASN L 229 68.868 28.865 74.586 1.00 65.13 C +ATOM 22626 O ASN L 229 69.246 28.338 75.638 1.00 86.96 O +ATOM 22627 CB ASN L 229 69.746 31.179 73.971 1.00 86.65 C +ATOM 22628 CG ASN L 229 70.329 31.603 75.300 1.00 64.30 C +ATOM 22629 OD1 ASN L 229 71.247 30.961 75.835 1.00 53.31 O +ATOM 22630 ND2 ASN L 229 69.860 32.746 75.790 1.00 58.44 N +ATOM 22631 N ASP L 230 67.612 28.841 74.159 1.00 50.31 N +ATOM 22632 CA ASP L 230 66.571 28.200 74.932 1.00 62.84 C +ATOM 22633 C ASP L 230 66.859 26.712 75.004 1.00 54.77 C +ATOM 22634 O ASP L 230 66.660 26.078 76.037 1.00 55.40 O +ATOM 22635 CB ASP L 230 65.204 28.462 74.286 1.00 73.10 C +ATOM 22636 CG ASP L 230 64.048 27.873 75.089 1.00 76.86 C +ATOM 22637 OD1 ASP L 230 63.715 28.448 76.144 1.00 85.19 O +ATOM 22638 OD2 ASP L 230 63.461 26.861 74.670 1.00 76.42 O +ATOM 22639 N GLY L 231 67.328 26.178 73.900 1.00 50.34 N +ATOM 22640 CA GLY L 231 67.595 24.766 73.819 1.00 54.99 C +ATOM 22641 C GLY L 231 68.783 24.416 74.677 1.00 64.71 C +ATOM 22642 O GLY L 231 68.851 23.309 75.238 1.00 90.63 O +ATOM 22643 N ILE L 232 69.748 25.332 74.755 1.00 74.93 N +ATOM 22644 CA ILE L 232 70.924 25.139 75.616 1.00 98.32 C +ATOM 22645 C ILE L 232 70.468 25.000 77.066 1.00111.85 C +ATOM 22646 O ILE L 232 70.863 24.066 77.762 1.00 78.54 O +ATOM 22647 CB ILE L 232 71.949 26.311 75.476 1.00109.31 C +ATOM 22648 CG1 ILE L 232 72.694 26.196 74.144 1.00 98.51 C +ATOM 22649 CG2 ILE L 232 72.950 26.330 76.636 1.00129.88 C +ATOM 22650 CD1 ILE L 232 73.390 27.472 73.716 1.00 97.51 C +ATOM 22651 N ASP L 233 69.647 25.954 77.514 1.00141.13 N +ATOM 22652 CA ASP L 233 69.086 25.941 78.869 1.00111.95 C +ATOM 22653 C ASP L 233 68.340 24.644 79.148 1.00102.70 C +ATOM 22654 O ASP L 233 68.570 24.000 80.171 1.00140.22 O +ATOM 22655 CB ASP L 233 68.130 27.120 79.077 1.00 89.75 C +ATOM 22656 CG ASP L 233 68.836 28.462 79.052 1.00 96.96 C +ATOM 22657 OD1 ASP L 233 70.039 28.544 78.637 1.00 96.01 O +ATOM 22658 OD2 ASP L 233 68.155 29.488 79.355 1.00 89.52 O +ATOM 22659 N ARG L 234 67.448 24.269 78.246 1.00 90.98 N +ATOM 22660 CA ARG L 234 66.578 23.129 78.482 1.00 88.36 C +ATOM 22661 C ARG L 234 67.245 21.767 78.279 1.00 83.10 C +ATOM 22662 O ARG L 234 66.590 20.723 78.396 1.00 73.68 O +ATOM 22663 CB ARG L 234 65.316 23.270 77.625 1.00 80.30 C +ATOM 22664 CG ARG L 234 64.407 24.345 78.173 1.00 92.05 C +ATOM 22665 CD ARG L 234 63.449 24.879 77.130 1.00111.61 C +ATOM 22666 NE ARG L 234 62.680 26.027 77.632 1.00115.30 N +ATOM 22667 CZ ARG L 234 61.352 26.108 77.645 1.00105.44 C +ATOM 22668 NH1 ARG L 234 60.617 25.074 77.220 1.00128.71 N +ATOM 22669 NH2 ARG L 234 60.760 27.214 78.088 1.00 70.31 N +ATOM 22670 N GLY L 235 68.512 21.765 77.871 1.00 94.43 N +ATOM 22671 CA GLY L 235 69.212 20.505 77.585 1.00108.02 C +ATOM 22672 C GLY L 235 68.772 19.745 76.314 1.00 87.47 C +ATOM 22673 O GLY L 235 68.837 18.531 76.272 1.00 50.32 O +ATOM 22674 N LEU L 236 68.397 20.474 75.261 1.00 83.45 N +ATOM 22675 CA LEU L 236 68.275 19.887 73.923 1.00 66.01 C +ATOM 22676 C LEU L 236 69.655 19.636 73.319 1.00 65.42 C +ATOM 22677 O LEU L 236 69.951 18.530 72.889 1.00 70.70 O +ATOM 22678 CB LEU L 236 67.492 20.807 72.987 1.00 87.85 C +ATOM 22679 CG LEU L 236 65.954 20.778 73.051 1.00104.10 C +ATOM 22680 CD1 LEU L 236 65.462 21.603 74.233 1.00134.66 C +ATOM 22681 CD2 LEU L 236 65.357 21.318 71.767 1.00 91.06 C +ATOM 22682 N TRP L 237 70.527 20.648 73.359 1.00 67.00 N +ATOM 22683 CA TRP L 237 71.910 20.540 72.851 1.00 71.28 C +ATOM 22684 C TRP L 237 72.928 21.275 73.755 1.00 82.98 C +ATOM 22685 O TRP L 237 72.539 21.938 74.707 1.00 90.41 O +ATOM 22686 CB TRP L 237 71.969 21.143 71.473 1.00 62.37 C +ATOM 22687 CG TRP L 237 71.073 22.289 71.317 1.00 63.08 C +ATOM 22688 CD1 TRP L 237 71.206 23.503 71.907 1.00 75.29 C +ATOM 22689 CD2 TRP L 237 69.893 22.368 70.499 1.00 76.91 C +ATOM 22690 NE1 TRP L 237 70.177 24.336 71.519 1.00 81.14 N +ATOM 22691 CE2 TRP L 237 69.357 23.659 70.657 1.00 88.19 C +ATOM 22692 CE3 TRP L 237 69.229 21.472 69.655 1.00 98.11 C +ATOM 22693 CZ2 TRP L 237 68.173 24.074 70.005 1.00106.17 C +ATOM 22694 CZ3 TRP L 237 68.030 21.883 69.012 1.00 89.63 C +ATOM 22695 CH2 TRP L 237 67.525 23.165 69.198 1.00 94.59 C +ATOM 22696 N ASP L 238 74.228 21.040 73.565 1.00 96.87 N +ATOM 22697 CA ASP L 238 75.266 21.654 74.462 1.00100.51 C +ATOM 22698 C ASP L 238 76.482 22.174 73.757 1.00 85.51 C +ATOM 22699 O ASP L 238 76.838 21.713 72.660 1.00 89.66 O +ATOM 22700 CB ASP L 238 75.645 20.796 75.695 1.00107.35 C +ATOM 22701 CG ASP L 238 75.353 21.524 76.990 1.00102.05 C +ATOM 22702 OD1 ASP L 238 75.648 22.736 77.185 1.00 79.31 O +ATOM 22703 OD2 ASP L 238 74.843 20.837 77.813 1.00110.04 O +ATOM 22704 N LEU L 239 77.154 23.067 74.475 1.00 75.52 N +ATOM 22705 CA LEU L 239 78.279 23.796 73.945 1.00 80.89 C +ATOM 22706 C LEU L 239 79.549 22.963 73.928 1.00 87.21 C +ATOM 22707 O LEU L 239 79.786 22.140 74.829 1.00114.28 O +ATOM 22708 CB LEU L 239 78.534 25.066 74.762 1.00 69.08 C +ATOM 22709 CG LEU L 239 77.585 26.242 74.607 1.00 64.53 C +ATOM 22710 CD1 LEU L 239 78.092 27.435 75.400 1.00 48.74 C +ATOM 22711 CD2 LEU L 239 77.451 26.608 73.149 1.00 77.60 C +ATOM 22712 N GLN L 240 80.367 23.184 72.905 1.00 79.55 N +ATOM 22713 CA GLN L 240 81.707 22.599 72.852 1.00 87.39 C +ATOM 22714 C GLN L 240 82.536 23.008 74.066 1.00 76.13 C +ATOM 22715 O GLN L 240 83.001 22.154 74.830 1.00 75.78 O +ATOM 22716 CB GLN L 240 82.429 23.049 71.585 1.00108.45 C +ATOM 22717 CG GLN L 240 83.768 22.356 71.340 1.00112.40 C +ATOM 22718 CD GLN L 240 83.592 20.869 71.075 1.00121.75 C +ATOM 22719 OE1 GLN L 240 83.279 20.465 69.955 1.00116.89 O +ATOM 22720 NE2 GLN L 240 83.769 20.048 72.111 1.00130.74 N +ATOM 22721 N ASN L 241 82.640 24.314 74.274 1.00 78.83 N +ATOM 22722 CA ASN L 241 83.351 24.879 75.424 1.00111.58 C +ATOM 22723 C ASN L 241 82.406 25.397 76.499 1.00139.21 C +ATOM 22724 O ASN L 241 81.661 26.375 76.267 1.00176.49 O +ATOM 22725 CB ASN L 241 84.206 26.040 74.968 1.00133.46 C +ATOM 22726 CG ASN L 241 85.646 25.662 74.813 1.00167.00 C +ATOM 22727 OD1 ASN L 241 86.466 25.978 75.671 1.00176.85 O +ATOM 22728 ND2 ASN L 241 85.970 24.962 73.727 1.00202.99 N +ATOM 22729 N LYS L 242 82.394 24.731 77.658 1.00133.42 N +ATOM 22730 CA LYS L 242 81.443 25.133 78.716 1.00113.02 C +ATOM 22731 C LYS L 242 81.879 26.471 79.200 1.00 89.74 C +ATOM 22732 O LYS L 242 81.066 27.164 79.806 1.00110.39 O +ATOM 22733 CB LYS L 242 81.426 24.274 79.969 1.00113.46 C +ATOM 22734 CG LYS L 242 82.434 23.162 79.951 1.00116.36 C +ATOM 22735 CD LYS L 242 81.937 21.903 80.645 1.00133.10 C +ATOM 22736 CE LYS L 242 82.257 20.670 79.818 1.00160.31 C +ATOM 22737 NZ LYS L 242 81.935 19.413 80.542 1.00192.33 N +ATOM 22738 N ALA L 243 83.174 26.766 79.030 1.00 66.97 N +ATOM 22739 CA ALA L 243 83.759 28.077 79.378 1.00 69.74 C +ATOM 22740 C ALA L 243 83.140 29.197 78.561 1.00 94.55 C +ATOM 22741 O ALA L 243 83.159 30.359 78.981 1.00112.62 O +ATOM 22742 CB ALA L 243 85.242 28.076 79.140 1.00 48.74 C +ATOM 22743 N GLU L 244 82.476 28.839 77.462 1.00 99.28 N +ATOM 22744 CA GLU L 244 81.844 29.842 76.619 1.00 91.71 C +ATOM 22745 C GLU L 244 80.377 30.117 76.947 1.00 70.02 C +ATOM 22746 O GLU L 244 79.675 30.735 76.156 1.00 94.90 O +ATOM 22747 CB GLU L 244 82.002 29.441 75.146 1.00128.16 C +ATOM 22748 CG GLU L 244 83.433 29.580 74.617 1.00129.77 C +ATOM 22749 CD GLU L 244 83.543 29.445 73.110 1.00120.21 C +ATOM 22750 OE1 GLU L 244 83.439 28.302 72.601 1.00129.47 O +ATOM 22751 OE2 GLU L 244 83.658 30.494 72.441 1.00106.09 O +ATOM 22752 N ARG L 245 79.902 29.579 78.060 1.00 65.95 N +ATOM 22753 CA ARG L 245 78.547 29.807 78.578 1.00 82.31 C +ATOM 22754 C ARG L 245 78.256 31.328 78.720 1.00 74.96 C +ATOM 22755 O ARG L 245 77.133 31.824 78.362 1.00 95.57 O +ATOM 22756 CB ARG L 245 78.414 29.024 79.982 1.00 94.17 C +ATOM 22757 CG ARG L 245 78.232 27.501 79.861 1.00 93.58 C +ATOM 22758 CD ARG L 245 78.524 26.735 81.093 1.00 93.85 C +ATOM 22759 NE ARG L 245 78.244 25.328 80.977 1.00104.77 N +ATOM 22760 CZ ARG L 245 78.303 24.472 81.988 1.00126.15 C +ATOM 22761 NH1 ARG L 245 78.464 24.900 83.235 1.00142.36 N +ATOM 22762 NH2 ARG L 245 78.119 23.192 81.761 1.00123.04 N +ATOM 22763 N GLN L 246 79.269 32.078 79.149 1.00 64.44 N +ATOM 22764 CA GLN L 246 79.072 33.494 79.424 1.00 74.57 C +ATOM 22765 C GLN L 246 79.508 34.347 78.241 1.00 71.56 C +ATOM 22766 O GLN L 246 79.733 35.549 78.381 1.00 58.49 O +ATOM 22767 CB GLN L 246 79.842 33.926 80.673 1.00 76.98 C +ATOM 22768 CG GLN L 246 79.278 33.403 81.983 1.00 78.81 C +ATOM 22769 CD GLN L 246 79.615 31.957 82.227 1.00 91.72 C +ATOM 22770 OE1 GLN L 246 80.724 31.522 81.975 1.00 97.64 O +ATOM 22771 NE2 GLN L 246 78.623 31.184 82.662 1.00121.90 N +ATOM 22772 N ASN L 247 79.509 33.746 77.060 1.00 91.62 N +ATOM 22773 CA ASN L 247 79.602 34.474 75.788 1.00105.72 C +ATOM 22774 C ASN L 247 78.762 35.750 75.758 1.00 95.48 C +ATOM 22775 O ASN L 247 77.604 35.751 76.213 1.00118.61 O +ATOM 22776 CB ASN L 247 79.140 33.558 74.646 1.00108.30 C +ATOM 22777 CG ASN L 247 79.783 33.901 73.334 1.00100.13 C +ATOM 22778 OD1 ASN L 247 79.141 34.435 72.439 1.00 83.65 O +ATOM 22779 ND2 ASN L 247 81.073 33.615 73.219 1.00110.10 N +ATOM 22780 N ASP L 248 79.339 36.828 75.230 1.00 83.72 N +ATOM 22781 CA ASP L 248 78.673 38.145 75.214 1.00 95.96 C +ATOM 22782 C ASP L 248 77.273 38.039 74.596 1.00 93.12 C +ATOM 22783 O ASP L 248 76.298 38.606 75.104 1.00 94.37 O +ATOM 22784 CB ASP L 248 79.500 39.161 74.408 1.00 98.32 C +ATOM 22785 CG ASP L 248 80.770 39.577 75.111 1.00102.60 C +ATOM 22786 OD1 ASP L 248 80.750 39.751 76.352 1.00134.96 O +ATOM 22787 OD2 ASP L 248 81.791 39.763 74.419 1.00 99.10 O +ATOM 22788 N ILE L 249 77.199 37.327 73.479 1.00 89.96 N +ATOM 22789 CA ILE L 249 75.979 37.236 72.696 1.00 91.93 C +ATOM 22790 C ILE L 249 74.946 36.441 73.479 1.00 84.56 C +ATOM 22791 O ILE L 249 73.807 36.875 73.647 1.00 93.23 O +ATOM 22792 CB ILE L 249 76.259 36.576 71.325 1.00 96.03 C +ATOM 22793 CG1 ILE L 249 77.219 37.449 70.490 1.00107.89 C +ATOM 22794 CG2 ILE L 249 74.968 36.378 70.562 1.00 85.27 C +ATOM 22795 CD1 ILE L 249 77.938 36.705 69.381 1.00107.21 C +ATOM 22796 N LEU L 250 75.372 35.296 73.997 1.00 89.02 N +ATOM 22797 CA LEU L 250 74.475 34.396 74.727 1.00 83.32 C +ATOM 22798 C LEU L 250 73.864 35.055 75.959 1.00 81.09 C +ATOM 22799 O LEU L 250 72.696 34.820 76.277 1.00 83.90 O +ATOM 22800 CB LEU L 250 75.212 33.111 75.123 1.00 72.14 C +ATOM 22801 CG LEU L 250 75.336 32.072 74.006 1.00 71.68 C +ATOM 22802 CD1 LEU L 250 76.315 30.962 74.365 1.00 63.37 C +ATOM 22803 CD2 LEU L 250 73.965 31.480 73.679 1.00 81.77 C +ATOM 22804 N VAL L 251 74.654 35.874 76.646 1.00 84.09 N +ATOM 22805 CA VAL L 251 74.172 36.562 77.854 1.00 91.68 C +ATOM 22806 C VAL L 251 73.303 37.750 77.476 1.00 91.85 C +ATOM 22807 O VAL L 251 72.471 38.205 78.263 1.00121.57 O +ATOM 22808 CB VAL L 251 75.332 37.013 78.788 1.00 91.47 C +ATOM 22809 CG1 VAL L 251 76.231 35.818 79.153 1.00116.23 C +ATOM 22810 CG2 VAL L 251 76.159 38.125 78.164 1.00 85.49 C +ATOM 22811 N LYS L 252 73.521 38.274 76.274 1.00 87.53 N +ATOM 22812 CA LYS L 252 72.721 39.395 75.773 1.00 76.28 C +ATOM 22813 C LYS L 252 71.290 38.925 75.499 1.00 66.38 C +ATOM 22814 O LYS L 252 70.323 39.569 75.910 1.00 73.43 O +ATOM 22815 CB LYS L 252 73.383 39.965 74.516 1.00 81.92 C +ATOM 22816 CG LYS L 252 72.643 41.105 73.852 1.00 96.03 C +ATOM 22817 CD LYS L 252 73.376 41.555 72.590 1.00104.40 C +ATOM 22818 CE LYS L 252 72.426 41.709 71.409 1.00112.15 C +ATOM 22819 NZ LYS L 252 73.140 41.894 70.118 1.00109.26 N +ATOM 22820 N TYR L 253 71.163 37.766 74.859 1.00 73.38 N +ATOM 22821 CA TYR L 253 69.842 37.208 74.496 1.00 81.21 C +ATOM 22822 C TYR L 253 69.205 36.606 75.719 1.00 73.38 C +ATOM 22823 O TYR L 253 67.984 36.573 75.844 1.00 63.68 O +ATOM 22824 CB TYR L 253 69.938 36.174 73.344 1.00 92.21 C +ATOM 22825 CG TYR L 253 70.152 36.825 71.997 1.00 98.32 C +ATOM 22826 CD1 TYR L 253 71.454 37.130 71.584 1.00129.48 C +ATOM 22827 CD2 TYR L 253 69.090 37.231 71.186 1.00 68.64 C +ATOM 22828 CE1 TYR L 253 71.709 37.809 70.409 1.00129.51 C +ATOM 22829 CE2 TYR L 253 69.349 37.901 70.000 1.00 83.04 C +ATOM 22830 CZ TYR L 253 70.652 38.208 69.624 1.00114.76 C +ATOM 22831 OH TYR L 253 70.939 38.985 68.495 1.00139.70 O +ATOM 22832 N ARG L 254 70.013 36.128 76.688 1.00 88.02 N +ATOM 22833 CA ARG L 254 69.545 35.604 77.907 1.00 96.99 C +ATOM 22834 C ARG L 254 68.955 36.771 78.723 1.00 82.21 C +ATOM 22835 O ARG L 254 67.986 36.517 79.442 1.00 85.55 O +ATOM 22836 CB ARG L 254 70.815 35.141 78.622 1.00 96.89 C +ATOM 22837 CG ARG L 254 70.751 35.254 80.137 1.00 84.82 C +ATOM 22838 CD ARG L 254 70.052 34.052 80.751 1.00 74.12 C +ATOM 22839 NE ARG L 254 69.379 33.237 79.744 1.00 70.43 N +ATOM 22840 CZ ARG L 254 69.535 31.923 79.619 1.00 68.53 C +ATOM 22841 NH1 ARG L 254 70.345 31.269 80.441 1.00 62.72 N +ATOM 22842 NH2 ARG L 254 68.882 31.262 78.673 1.00 91.33 N +ATOM 22843 N HIS L 255 69.515 37.930 78.560 1.00 79.22 N +ATOM 22844 CA HIS L 255 69.025 39.130 79.222 1.00 80.29 C +ATOM 22845 C HIS L 255 67.717 39.632 78.619 1.00 81.65 C +ATOM 22846 O HIS L 255 66.864 40.139 79.338 1.00 89.27 O +ATOM 22847 CB HIS L 255 70.094 40.237 79.230 1.00 87.93 C +ATOM 22848 CG HIS L 255 70.714 40.462 80.585 1.00122.18 C +ATOM 22849 ND1 HIS L 255 70.152 41.307 81.520 1.00151.92 N +ATOM 22850 CD2 HIS L 255 71.777 39.882 81.203 1.00138.25 C +ATOM 22851 CE1 HIS L 255 70.847 41.261 82.643 1.00144.40 C +ATOM 22852 NE2 HIS L 255 71.845 40.412 82.474 1.00159.65 N +ATOM 22853 N MET L 256 67.533 39.446 77.316 1.00 99.67 N +ATOM 22854 CA MET L 256 66.295 39.889 76.664 1.00 99.21 C +ATOM 22855 C MET L 256 65.094 39.026 77.072 1.00 89.48 C +ATOM 22856 O MET L 256 63.954 39.508 77.076 1.00 96.74 O +ATOM 22857 CB MET L 256 66.447 39.899 75.137 1.00103.31 C +ATOM 22858 CG MET L 256 67.642 40.697 74.630 1.00113.02 C +ATOM 22859 SD MET L 256 67.572 41.171 72.880 1.00104.10 S +ATOM 22860 CE MET L 256 66.248 42.400 72.951 1.00105.42 C +ATOM 22861 N SER L 257 65.354 37.783 77.470 1.00 80.39 N +ATOM 22862 CA SER L 257 64.289 36.894 77.948 1.00 88.18 C +ATOM 22863 C SER L 257 63.760 37.321 79.313 1.00110.51 C +ATOM 22864 O SER L 257 62.776 38.044 79.437 1.00 85.05 O +ATOM 22865 CB SER L 257 64.811 35.465 78.060 1.00 87.58 C +ATOM 22866 OG SER L 257 65.534 35.110 76.922 1.00103.86 O +TER 22867 SER L 257 +ATOM 22868 N LEU M 2 75.412 56.180 48.116 1.00147.49 N +ATOM 22869 CA LEU M 2 74.033 56.348 48.686 1.00156.49 C +ATOM 22870 C LEU M 2 72.954 56.119 47.595 1.00137.32 C +ATOM 22871 O LEU M 2 72.256 57.062 47.147 1.00 71.57 O +ATOM 22872 CB LEU M 2 73.880 57.721 49.366 1.00165.16 C +ATOM 22873 CG LEU M 2 74.793 58.073 50.569 1.00130.74 C +ATOM 22874 CD1 LEU M 2 74.476 59.492 51.043 1.00109.89 C +ATOM 22875 CD2 LEU M 2 74.714 57.085 51.739 1.00109.67 C +ATOM 22876 N THR M 3 72.949 54.871 47.113 1.00141.21 N +ATOM 22877 CA THR M 3 71.867 54.268 46.341 1.00148.62 C +ATOM 22878 C THR M 3 71.674 52.773 46.711 1.00157.55 C +ATOM 22879 O THR M 3 70.778 52.102 46.187 1.00172.63 O +ATOM 22880 CB THR M 3 72.136 54.332 44.822 1.00140.23 C +ATOM 22881 OG1 THR M 3 73.240 53.465 44.487 1.00119.75 O +ATOM 22882 CG2 THR M 3 72.410 55.773 44.363 1.00139.50 C +ATOM 22883 N ALA M 4 72.560 52.237 47.544 1.00141.00 N +ATOM 22884 CA ALA M 4 72.376 50.902 48.135 1.00123.06 C +ATOM 22885 C ALA M 4 71.341 50.982 49.286 1.00115.77 C +ATOM 22886 O ALA M 4 70.733 52.032 49.493 1.00108.48 O +ATOM 22887 CB ALA M 4 73.726 50.342 48.592 1.00111.05 C +ATOM 22888 N PRO M 5 71.072 49.865 49.994 1.00119.47 N +ATOM 22889 CA PRO M 5 69.909 49.992 50.868 1.00111.85 C +ATOM 22890 C PRO M 5 70.174 50.791 52.161 1.00139.47 C +ATOM 22891 O PRO M 5 71.328 51.133 52.476 1.00192.07 O +ATOM 22892 CB PRO M 5 69.572 48.543 51.201 1.00109.92 C +ATOM 22893 CG PRO M 5 70.879 47.806 51.115 1.00129.64 C +ATOM 22894 CD PRO M 5 71.826 48.620 50.264 1.00133.07 C +ATOM 22895 N PRO M 6 69.102 51.141 52.887 1.00125.41 N +ATOM 22896 CA PRO M 6 69.225 51.713 54.233 1.00114.42 C +ATOM 22897 C PRO M 6 69.518 50.649 55.282 1.00107.02 C +ATOM 22898 O PRO M 6 69.126 49.494 55.097 1.00 97.34 O +ATOM 22899 CB PRO M 6 67.853 52.375 54.478 1.00114.14 C +ATOM 22900 CG PRO M 6 66.927 51.835 53.460 1.00 99.95 C +ATOM 22901 CD PRO M 6 67.734 51.221 52.347 1.00123.66 C +ATOM 22902 N LYS M 7 70.161 51.044 56.383 1.00103.91 N +ATOM 22903 CA LYS M 7 70.527 50.089 57.433 1.00109.80 C +ATOM 22904 C LYS M 7 69.506 50.037 58.565 1.00 83.47 C +ATOM 22905 O LYS M 7 68.620 50.907 58.633 1.00 64.46 O +ATOM 22906 CB LYS M 7 71.919 50.391 57.993 1.00118.64 C +ATOM 22907 CG LYS M 7 73.052 50.157 57.014 1.00147.15 C +ATOM 22908 CD LYS M 7 73.633 51.449 56.441 1.00133.18 C +ATOM 22909 CE LYS M 7 74.951 51.178 55.731 1.00139.90 C +ATOM 22910 NZ LYS M 7 75.203 52.142 54.626 1.00131.04 N +ATOM 22911 N GLU M 8 69.628 49.000 59.407 1.00 74.60 N +ATOM 22912 CA GLU M 8 68.551 48.598 60.339 1.00 80.19 C +ATOM 22913 C GLU M 8 68.325 49.639 61.451 1.00 67.60 C +ATOM 22914 O GLU M 8 69.225 50.055 62.174 1.00 52.88 O +ATOM 22915 CB GLU M 8 68.668 47.112 60.840 1.00 95.94 C +ATOM 22916 CG GLU M 8 68.620 46.011 59.699 1.00144.37 C +ATOM 22917 CD GLU M 8 67.176 45.869 59.054 1.00154.23 C +ATOM 22918 OE1 GLU M 8 66.757 46.878 58.460 1.00166.34 O +ATOM 22919 OE2 GLU M 8 66.427 44.816 59.033 1.00 87.14 O +ATOM 22920 N ALA M 9 67.123 50.190 61.455 1.00 75.10 N +ATOM 22921 CA ALA M 9 66.701 51.124 62.481 1.00 73.63 C +ATOM 22922 C ALA M 9 65.938 50.334 63.540 1.00 66.26 C +ATOM 22923 O ALA M 9 64.840 49.842 63.268 1.00 58.49 O +ATOM 22924 CB ALA M 9 65.814 52.212 61.869 1.00 79.68 C +ATOM 22925 N ALA M 10 66.494 50.302 64.754 1.00 56.13 N +ATOM 22926 CA ALA M 10 65.954 49.559 65.900 1.00 55.56 C +ATOM 22927 C ALA M 10 66.413 48.130 65.836 1.00 66.68 C +ATOM 22928 O ALA M 10 66.831 47.638 64.782 1.00 71.78 O +ATOM 22929 CB ALA M 10 64.430 49.637 65.986 1.00 57.89 C +ATOM 22930 N ARG M 11 66.370 47.466 66.980 1.00 82.58 N +ATOM 22931 CA ARG M 11 66.828 46.075 67.086 1.00111.08 C +ATOM 22932 C ARG M 11 65.618 45.136 67.078 1.00 94.26 C +ATOM 22933 O ARG M 11 64.562 45.514 67.550 1.00 87.27 O +ATOM 22934 CB ARG M 11 67.638 45.871 68.391 1.00144.40 C +ATOM 22935 CG ARG M 11 66.832 46.023 69.676 1.00161.72 C +ATOM 22936 CD ARG M 11 67.701 46.442 70.856 1.00169.49 C +ATOM 22937 NE ARG M 11 67.319 47.755 71.371 1.00187.36 N +ATOM 22938 CZ ARG M 11 67.877 48.326 72.435 1.00192.17 C +ATOM 22939 NH1 ARG M 11 68.849 47.707 73.090 1.00183.31 N +ATOM 22940 NH2 ARG M 11 67.479 49.527 72.836 1.00201.78 N +ATOM 22941 N PRO M 12 65.787 43.892 66.590 1.00 90.25 N +ATOM 22942 CA PRO M 12 64.790 42.899 66.925 1.00 91.98 C +ATOM 22943 C PRO M 12 64.734 42.655 68.433 1.00103.89 C +ATOM 22944 O PRO M 12 65.684 42.145 69.036 1.00 99.81 O +ATOM 22945 CB PRO M 12 65.269 41.642 66.185 1.00 94.89 C +ATOM 22946 CG PRO M 12 66.354 42.093 65.262 1.00 89.15 C +ATOM 22947 CD PRO M 12 66.946 43.287 65.911 1.00 93.53 C +ATOM 22948 N THR M 13 63.610 43.023 69.034 1.00104.15 N +ATOM 22949 CA THR M 13 63.290 42.610 70.388 1.00107.61 C +ATOM 22950 C THR M 13 62.387 41.389 70.387 1.00 95.33 C +ATOM 22951 O THR M 13 61.768 41.046 69.382 1.00 88.25 O +ATOM 22952 CB THR M 13 62.544 43.720 71.126 1.00108.60 C +ATOM 22953 OG1 THR M 13 62.467 43.397 72.522 1.00205.02 O +ATOM 22954 CG2 THR M 13 61.129 43.961 70.526 1.00 83.97 C +ATOM 22955 N LEU M 14 62.312 40.695 71.509 1.00 79.97 N +ATOM 22956 CA LEU M 14 61.314 39.661 71.587 1.00 79.52 C +ATOM 22957 C LEU M 14 59.970 40.309 71.695 1.00 65.88 C +ATOM 22958 O LEU M 14 59.934 41.408 72.195 1.00 52.80 O +ATOM 22959 CB LEU M 14 61.600 38.843 72.813 1.00 69.32 C +ATOM 22960 CG LEU M 14 62.802 37.923 72.829 1.00 80.32 C +ATOM 22961 CD1 LEU M 14 63.318 37.785 74.248 1.00 76.17 C +ATOM 22962 CD2 LEU M 14 62.347 36.577 72.276 1.00103.75 C +ATOM 22963 N MET M 15 58.883 39.603 71.384 1.00 74.74 N +ATOM 22964 CA MET M 15 57.612 40.292 71.160 1.00 90.42 C +ATOM 22965 C MET M 15 57.022 40.933 72.446 1.00 85.52 C +ATOM 22966 O MET M 15 56.773 40.247 73.440 1.00119.48 O +ATOM 22967 CB MET M 15 56.581 39.366 70.501 1.00 99.49 C +ATOM 22968 CG MET M 15 55.658 40.134 69.584 1.00113.57 C +ATOM 22969 SD MET M 15 53.922 39.755 69.488 1.00124.62 S +ATOM 22970 CE MET M 15 53.551 38.683 70.868 1.00 93.27 C +ATOM 22971 N PRO M 16 56.818 42.248 72.428 1.00 71.92 N +ATOM 22972 CA PRO M 16 56.450 43.044 73.583 1.00 75.83 C +ATOM 22973 C PRO M 16 55.073 42.708 74.158 1.00 86.01 C +ATOM 22974 O PRO M 16 54.079 43.407 73.887 1.00130.56 O +ATOM 22975 CB PRO M 16 56.475 44.473 73.034 1.00 91.64 C +ATOM 22976 CG PRO M 16 56.262 44.329 71.565 1.00 99.32 C +ATOM 22977 CD PRO M 16 56.976 43.070 71.216 1.00 92.34 C +ATOM 22978 N ARG M 17 55.023 41.687 75.004 1.00 73.65 N +ATOM 22979 CA ARG M 17 53.801 41.345 75.743 1.00 74.96 C +ATOM 22980 C ARG M 17 53.770 42.096 77.049 1.00 73.53 C +ATOM 22981 O ARG M 17 54.820 42.361 77.622 1.00 76.83 O +ATOM 22982 CB ARG M 17 53.760 39.845 76.007 1.00 86.78 C +ATOM 22983 CG ARG M 17 53.123 39.052 74.873 1.00121.71 C +ATOM 22984 CD ARG M 17 53.450 37.564 74.914 1.00108.30 C +ATOM 22985 NE ARG M 17 54.811 37.303 74.443 1.00132.14 N +ATOM 22986 CZ ARG M 17 55.401 36.113 74.493 1.00154.25 C +ATOM 22987 NH1 ARG M 17 54.732 35.081 74.998 1.00177.68 N +ATOM 22988 NH2 ARG M 17 56.647 35.952 74.032 1.00134.64 N +ATOM 22989 N ALA M 18 52.584 42.474 77.524 1.00 93.58 N +ATOM 22990 CA ALA M 18 52.478 43.290 78.757 1.00106.27 C +ATOM 22991 C ALA M 18 51.817 42.554 79.928 1.00 95.75 C +ATOM 22992 O ALA M 18 52.360 41.541 80.406 1.00104.61 O +ATOM 22993 CB ALA M 18 51.771 44.611 78.487 1.00112.26 C +ATOM 22994 N GLN M 19 50.693 43.077 80.421 1.00 80.40 N +ATOM 22995 CA GLN M 19 50.227 42.720 81.764 1.00118.30 C +ATOM 22996 C GLN M 19 49.718 41.275 81.831 1.00118.57 C +ATOM 22997 O GLN M 19 50.082 40.492 82.734 1.00106.28 O +ATOM 22998 CB GLN M 19 49.122 43.682 82.218 1.00118.89 C +ATOM 22999 CG GLN M 19 48.672 43.484 83.665 1.00117.22 C +ATOM 23000 CD GLN M 19 49.836 43.534 84.651 1.00117.44 C +ATOM 23001 OE1 GLN M 19 50.451 44.582 84.848 1.00126.12 O +ATOM 23002 NE2 GLN M 19 50.133 42.400 85.282 1.00106.51 N +ATOM 23003 N SER M 20 48.835 40.961 80.896 1.00109.30 N +ATOM 23004 CA SER M 20 48.339 39.617 80.708 1.00109.26 C +ATOM 23005 C SER M 20 49.469 38.589 80.823 1.00121.70 C +ATOM 23006 O SER M 20 49.350 37.605 81.558 1.00129.89 O +ATOM 23007 CB SER M 20 47.675 39.535 79.330 1.00127.42 C +ATOM 23008 OG SER M 20 46.735 40.590 79.150 1.00154.31 O +ATOM 23009 N TYR M 21 50.562 38.829 80.092 1.00129.35 N +ATOM 23010 CA TYR M 21 51.751 37.966 80.127 1.00112.31 C +ATOM 23011 C TYR M 21 52.324 37.795 81.535 1.00124.21 C +ATOM 23012 O TYR M 21 52.581 36.669 81.988 1.00125.20 O +ATOM 23013 CB TYR M 21 52.840 38.529 79.207 1.00 96.38 C +ATOM 23014 CG TYR M 21 54.082 37.673 79.153 1.00103.16 C +ATOM 23015 CD1 TYR M 21 54.104 36.485 78.410 1.00114.20 C +ATOM 23016 CD2 TYR M 21 55.226 38.026 79.844 1.00 99.36 C +ATOM 23017 CE1 TYR M 21 55.225 35.677 78.368 1.00 91.13 C +ATOM 23018 CE2 TYR M 21 56.358 37.229 79.794 1.00 97.77 C +ATOM 23019 CZ TYR M 21 56.343 36.058 79.058 1.00 81.35 C +ATOM 23020 OH TYR M 21 57.443 35.251 78.997 1.00 81.25 O +ATOM 23021 N LYS M 22 52.517 38.914 82.226 1.00126.10 N +ATOM 23022 CA LYS M 22 53.104 38.903 83.569 1.00111.92 C +ATOM 23023 C LYS M 22 52.266 38.099 84.559 1.00112.08 C +ATOM 23024 O LYS M 22 52.800 37.370 85.390 1.00122.69 O +ATOM 23025 CB LYS M 22 53.267 40.329 84.081 1.00104.11 C +ATOM 23026 CG LYS M 22 54.545 41.008 83.616 1.00117.37 C +ATOM 23027 CD LYS M 22 55.781 40.981 84.410 1.00139.94 C +ATOM 23028 CE LYS M 22 56.429 42.233 84.024 1.00145.64 C +ATOM 23029 NZ LYS M 22 57.135 43.015 85.054 1.00163.55 N +ATOM 23030 N ASP M 23 50.947 38.251 84.469 1.00106.44 N +ATOM 23031 CA ASP M 23 50.018 37.442 85.263 1.00102.08 C +ATOM 23032 C ASP M 23 50.150 35.963 84.897 1.00 87.49 C +ATOM 23033 O ASP M 23 50.166 35.091 85.763 1.00 83.35 O +ATOM 23034 CB ASP M 23 48.565 37.908 85.033 1.00105.36 C +ATOM 23035 CG ASP M 23 48.293 39.267 85.607 1.00125.35 C +ATOM 23036 OD1 ASP M 23 48.829 39.554 86.700 1.00130.51 O +ATOM 23037 OD2 ASP M 23 47.638 40.083 84.918 1.00147.41 O +ATOM 23038 N LEU M 24 50.179 35.698 83.594 1.00 93.06 N +ATOM 23039 CA LEU M 24 50.124 34.336 83.056 1.00 95.81 C +ATOM 23040 C LEU M 24 51.361 33.534 83.465 1.00 96.24 C +ATOM 23041 O LEU M 24 51.277 32.310 83.699 1.00 65.98 O +ATOM 23042 CB LEU M 24 49.998 34.388 81.523 1.00 93.10 C +ATOM 23043 CG LEU M 24 49.940 33.052 80.772 1.00 99.51 C +ATOM 23044 CD1 LEU M 24 48.519 32.522 80.690 1.00101.99 C +ATOM 23045 CD2 LEU M 24 50.515 33.223 79.374 1.00128.35 C +ATOM 23046 N THR M 25 52.500 34.226 83.545 1.00 93.83 N +ATOM 23047 CA THR M 25 53.770 33.570 83.840 1.00110.81 C +ATOM 23048 C THR M 25 53.896 33.250 85.326 1.00113.38 C +ATOM 23049 O THR M 25 54.256 32.118 85.704 1.00105.43 O +ATOM 23050 CB THR M 25 54.970 34.435 83.403 1.00108.12 C +ATOM 23051 OG1 THR M 25 54.763 35.787 83.813 1.00101.78 O +ATOM 23052 CG2 THR M 25 55.135 34.386 81.891 1.00100.27 C +ATOM 23053 N HIS M 26 53.566 34.232 86.160 1.00112.95 N +ATOM 23054 CA HIS M 26 53.678 34.097 87.612 1.00116.24 C +ATOM 23055 C HIS M 26 52.418 33.415 88.216 1.00116.62 C +ATOM 23056 O HIS M 26 52.001 33.736 89.319 1.00 95.77 O +ATOM 23057 CB HIS M 26 53.926 35.479 88.252 1.00109.16 C +ATOM 23058 CG HIS M 26 55.219 36.123 87.833 1.00110.82 C +ATOM 23059 ND1 HIS M 26 55.449 36.578 86.552 1.00122.64 N +ATOM 23060 CD2 HIS M 26 56.347 36.394 88.531 1.00117.86 C +ATOM 23061 CE1 HIS M 26 56.664 37.091 86.475 1.00108.16 C +ATOM 23062 NE2 HIS M 26 57.232 36.987 87.661 1.00116.57 N +ATOM 23063 N LEU M 27 51.845 32.445 87.504 1.00118.82 N +ATOM 23064 CA LEU M 27 50.750 31.630 88.043 1.00 90.98 C +ATOM 23065 C LEU M 27 51.286 30.420 88.802 1.00100.50 C +ATOM 23066 O LEU M 27 52.218 29.756 88.345 1.00110.47 O +ATOM 23067 CB LEU M 27 49.845 31.143 86.921 1.00 88.70 C +ATOM 23068 CG LEU M 27 48.734 32.118 86.524 1.00110.52 C +ATOM 23069 CD1 LEU M 27 48.092 31.700 85.209 1.00129.14 C +ATOM 23070 CD2 LEU M 27 47.683 32.222 87.606 1.00108.41 C +ATOM 23071 N PRO M 28 50.731 30.147 89.992 1.00104.43 N +ATOM 23072 CA PRO M 28 51.176 29.023 90.840 1.00101.41 C +ATOM 23073 C PRO M 28 51.018 27.698 90.133 1.00 94.57 C +ATOM 23074 O PRO M 28 49.970 27.432 89.575 1.00113.49 O +ATOM 23075 CB PRO M 28 50.221 29.078 92.033 1.00113.52 C +ATOM 23076 CG PRO M 28 49.019 29.812 91.535 1.00113.45 C +ATOM 23077 CD PRO M 28 49.550 30.819 90.555 1.00114.36 C +ATOM 23078 N ALA M 29 52.064 26.887 90.122 1.00104.88 N +ATOM 23079 CA ALA M 29 52.116 25.725 89.231 1.00104.88 C +ATOM 23080 C ALA M 29 51.177 24.595 89.718 1.00 90.63 C +ATOM 23081 O ALA M 29 50.965 24.430 90.908 1.00 89.92 O +ATOM 23082 CB ALA M 29 53.568 25.239 89.070 1.00 95.27 C +ATOM 23083 N PRO M 30 50.582 23.847 88.781 1.00 88.67 N +ATOM 23084 CA PRO M 30 49.803 22.657 89.087 1.00 85.76 C +ATOM 23085 C PRO M 30 50.656 21.459 89.557 1.00 77.37 C +ATOM 23086 O PRO M 30 51.887 21.501 89.456 1.00 62.52 O +ATOM 23087 CB PRO M 30 49.148 22.336 87.743 1.00101.76 C +ATOM 23088 CG PRO M 30 50.130 22.797 86.721 1.00117.09 C +ATOM 23089 CD PRO M 30 50.840 23.978 87.331 1.00112.59 C +ATOM 23090 N THR M 31 49.993 20.361 89.929 1.00 80.97 N +ATOM 23091 CA THR M 31 50.684 19.129 90.354 1.00 99.68 C +ATOM 23092 C THR M 31 51.454 18.419 89.233 1.00 90.70 C +ATOM 23093 O THR M 31 52.448 17.748 89.478 1.00 80.68 O +ATOM 23094 CB THR M 31 49.725 18.096 91.003 1.00123.88 C +ATOM 23095 OG1 THR M 31 48.624 17.799 90.131 1.00115.38 O +ATOM 23096 CG2 THR M 31 49.191 18.612 92.331 1.00144.12 C +ATOM 23097 N GLY M 32 51.000 18.592 88.001 1.00101.75 N +ATOM 23098 CA GLY M 32 51.795 18.250 86.821 1.00116.85 C +ATOM 23099 C GLY M 32 51.318 19.098 85.655 1.00118.31 C +ATOM 23100 O GLY M 32 50.162 19.526 85.650 1.00120.53 O +ATOM 23101 N LYS M 33 52.163 19.315 84.646 1.00102.37 N +ATOM 23102 CA LYS M 33 51.690 19.985 83.437 1.00 85.77 C +ATOM 23103 C LYS M 33 50.648 19.138 82.671 1.00 74.51 C +ATOM 23104 O LYS M 33 50.691 17.903 82.724 1.00 58.79 O +ATOM 23105 CB LYS M 33 52.844 20.359 82.522 1.00 91.75 C +ATOM 23106 CG LYS M 33 53.438 21.719 82.824 1.00102.35 C +ATOM 23107 CD LYS M 33 54.693 21.946 82.001 1.00131.70 C +ATOM 23108 CE LYS M 33 55.623 22.926 82.697 1.00129.41 C +ATOM 23109 NZ LYS M 33 56.928 23.041 81.999 1.00141.20 N +ATOM 23110 N ILE M 34 49.706 19.802 81.993 1.00 74.11 N +ATOM 23111 CA ILE M 34 48.652 19.108 81.275 1.00 85.32 C +ATOM 23112 C ILE M 34 48.959 19.148 79.764 1.00108.60 C +ATOM 23113 O ILE M 34 49.560 20.107 79.261 1.00105.09 O +ATOM 23114 CB ILE M 34 47.269 19.689 81.649 1.00 92.71 C +ATOM 23115 CG1 ILE M 34 46.963 19.410 83.123 1.00116.43 C +ATOM 23116 CG2 ILE M 34 46.145 19.073 80.825 1.00107.69 C +ATOM 23117 CD1 ILE M 34 46.804 20.661 83.958 1.00134.16 C +ATOM 23118 N PHE M 35 48.680 18.031 79.089 1.00107.59 N +ATOM 23119 CA PHE M 35 48.909 17.887 77.661 1.00107.81 C +ATOM 23120 C PHE M 35 47.758 18.512 76.882 1.00115.21 C +ATOM 23121 O PHE M 35 46.607 18.095 77.057 1.00168.31 O +ATOM 23122 CB PHE M 35 48.956 16.398 77.309 1.00127.65 C +ATOM 23123 CG PHE M 35 50.306 15.768 77.469 1.00114.75 C +ATOM 23124 CD1 PHE M 35 51.443 16.399 77.014 1.00 99.62 C +ATOM 23125 CD2 PHE M 35 50.410 14.485 77.976 1.00125.21 C +ATOM 23126 CE1 PHE M 35 52.673 15.798 77.144 1.00112.03 C +ATOM 23127 CE2 PHE M 35 51.635 13.864 78.075 1.00114.07 C +ATOM 23128 CZ PHE M 35 52.771 14.530 77.670 1.00112.22 C +ATOM 23129 N VAL M 36 48.060 19.431 75.966 1.00 76.05 N +ATOM 23130 CA VAL M 36 47.009 20.102 75.238 1.00 56.71 C +ATOM 23131 C VAL M 36 47.229 20.152 73.747 1.00 63.86 C +ATOM 23132 O VAL M 36 48.358 20.125 73.261 1.00 79.88 O +ATOM 23133 CB VAL M 36 46.876 21.518 75.745 1.00 63.95 C +ATOM 23134 CG1 VAL M 36 48.016 22.403 75.247 1.00 62.14 C +ATOM 23135 CG2 VAL M 36 45.528 22.082 75.334 1.00 73.40 C +ATOM 23136 N SER M 37 46.137 20.227 73.003 1.00 78.03 N +ATOM 23137 CA SER M 37 46.192 20.254 71.536 1.00 85.39 C +ATOM 23138 C SER M 37 45.486 21.492 71.061 1.00 65.74 C +ATOM 23139 O SER M 37 44.370 21.735 71.451 1.00 64.36 O +ATOM 23140 CB SER M 37 45.484 19.028 70.923 1.00 68.88 C +ATOM 23141 OG SER M 37 46.271 17.851 71.076 1.00 69.57 O +ATOM 23142 N VAL M 38 46.119 22.250 70.180 1.00 70.79 N +ATOM 23143 CA VAL M 38 45.397 23.278 69.449 1.00 73.35 C +ATOM 23144 C VAL M 38 45.472 23.026 67.943 1.00 80.36 C +ATOM 23145 O VAL M 38 46.578 23.031 67.386 1.00 97.29 O +ATOM 23146 CB VAL M 38 45.964 24.683 69.724 1.00 66.06 C +ATOM 23147 CG1 VAL M 38 45.191 25.707 68.917 1.00 70.09 C +ATOM 23148 CG2 VAL M 38 45.906 25.025 71.203 1.00 60.94 C +ATOM 23149 N TYR M 39 44.303 22.835 67.302 1.00 80.54 N +ATOM 23150 CA TYR M 39 44.201 22.527 65.857 1.00 67.21 C +ATOM 23151 C TYR M 39 44.056 23.820 65.057 1.00 63.92 C +ATOM 23152 O TYR M 39 44.899 24.120 64.203 1.00113.70 O +ATOM 23153 CB TYR M 39 43.042 21.568 65.571 1.00 58.58 C +ATOM 23154 CG TYR M 39 43.393 20.108 65.746 1.00 73.78 C +ATOM 23155 CD1 TYR M 39 43.499 19.525 67.012 1.00 72.54 C +ATOM 23156 CD2 TYR M 39 43.697 19.316 64.638 1.00112.21 C +ATOM 23157 CE1 TYR M 39 43.854 18.199 67.155 1.00 85.75 C +ATOM 23158 CE2 TYR M 39 44.046 17.974 64.757 1.00116.79 C +ATOM 23159 CZ TYR M 39 44.114 17.415 66.012 1.00118.94 C +ATOM 23160 OH TYR M 39 44.558 16.104 66.128 1.00114.88 O +ATOM 23161 N ASN M 40 43.140 24.682 65.465 1.00 53.74 N +ATOM 23162 CA ASN M 40 42.955 25.944 64.774 1.00 59.76 C +ATOM 23163 C ASN M 40 42.016 26.920 65.469 1.00 67.08 C +ATOM 23164 O ASN M 40 40.921 26.547 65.913 1.00 92.86 O +ATOM 23165 CB ASN M 40 42.395 25.673 63.392 1.00 76.12 C +ATOM 23166 CG ASN M 40 42.572 26.855 62.467 1.00136.12 C +ATOM 23167 OD1 ASN M 40 41.597 27.429 61.979 1.00185.80 O +ATOM 23168 ND2 ASN M 40 43.829 27.206 62.188 1.00182.62 N +ATOM 23169 N ILE M 41 42.428 28.177 65.560 1.00 85.43 N +ATOM 23170 CA ILE M 41 41.537 29.261 65.999 1.00 96.21 C +ATOM 23171 C ILE M 41 41.353 30.262 64.854 1.00113.45 C +ATOM 23172 O ILE M 41 42.322 30.886 64.404 1.00175.31 O +ATOM 23173 CB ILE M 41 42.096 30.003 67.240 1.00 77.33 C +ATOM 23174 CG1 ILE M 41 41.805 29.233 68.521 1.00 73.51 C +ATOM 23175 CG2 ILE M 41 41.412 31.344 67.377 1.00 81.71 C +ATOM 23176 CD1 ILE M 41 42.585 27.955 68.700 1.00 77.79 C +ATOM 23177 N GLN M 42 40.132 30.388 64.354 1.00100.87 N +ATOM 23178 CA GLN M 42 39.893 31.117 63.100 1.00 98.05 C +ATOM 23179 C GLN M 42 39.661 32.595 63.334 1.00 81.28 C +ATOM 23180 O GLN M 42 39.187 32.995 64.388 1.00 86.13 O +ATOM 23181 CB GLN M 42 38.687 30.539 62.345 1.00123.98 C +ATOM 23182 CG GLN M 42 38.878 29.116 61.845 1.00162.64 C +ATOM 23183 CD GLN M 42 37.872 28.143 62.451 1.00200.22 C +ATOM 23184 OE1 GLN M 42 36.779 27.953 61.916 1.00211.12 O +ATOM 23185 NE2 GLN M 42 38.227 27.544 63.587 1.00215.51 N +ATOM 23186 N ASP M 43 39.893 33.378 62.289 1.00 70.31 N +ATOM 23187 CA ASP M 43 39.454 34.756 62.220 1.00 73.07 C +ATOM 23188 C ASP M 43 37.973 34.820 61.839 1.00 84.16 C +ATOM 23189 O ASP M 43 37.617 35.358 60.787 1.00 86.08 O +ATOM 23190 CB ASP M 43 40.283 35.523 61.184 1.00 83.60 C +ATOM 23191 CG ASP M 43 40.057 37.042 61.242 1.00101.76 C +ATOM 23192 OD1 ASP M 43 40.118 37.618 62.348 1.00 94.23 O +ATOM 23193 OD2 ASP M 43 39.811 37.680 60.190 1.00125.94 O +ATOM 23194 N GLU M 44 37.100 34.335 62.730 1.00113.40 N +ATOM 23195 CA GLU M 44 35.630 34.327 62.508 1.00118.32 C +ATOM 23196 C GLU M 44 35.005 35.752 62.556 1.00 89.68 C +ATOM 23197 O GLU M 44 33.776 35.904 62.590 1.00 75.17 O +ATOM 23198 CB GLU M 44 34.925 33.404 63.533 1.00124.48 C +ATOM 23199 CG GLU M 44 34.848 31.920 63.144 1.00108.94 C +ATOM 23200 CD GLU M 44 34.174 31.019 64.206 1.00126.21 C +ATOM 23201 OE1 GLU M 44 33.111 31.389 64.782 1.00152.08 O +ATOM 23202 OE2 GLU M 44 34.703 29.920 64.483 1.00 95.97 O +ATOM 23203 N THR M 45 35.868 36.772 62.480 1.00 68.13 N +ATOM 23204 CA THR M 45 35.464 38.164 62.643 1.00 68.55 C +ATOM 23205 C THR M 45 34.661 38.702 61.454 1.00 80.95 C +ATOM 23206 O THR M 45 33.703 39.444 61.650 1.00 75.83 O +ATOM 23207 CB THR M 45 36.665 39.102 63.012 1.00 58.65 C +ATOM 23208 OG1 THR M 45 36.160 40.342 63.477 1.00 50.30 O +ATOM 23209 CG2 THR M 45 37.583 39.370 61.850 1.00 59.03 C +ATOM 23210 N GLY M 46 35.089 38.390 60.233 1.00112.54 N +ATOM 23211 CA GLY M 46 34.344 38.773 59.023 1.00117.97 C +ATOM 23212 C GLY M 46 34.733 40.142 58.468 1.00124.51 C +ATOM 23213 O GLY M 46 33.984 40.808 57.725 1.00 81.65 O +ATOM 23214 N GLN M 47 35.891 40.615 58.880 1.00104.98 N +ATOM 23215 CA GLN M 47 36.127 42.001 58.767 1.00 83.50 C +ATOM 23216 C GLN M 47 37.446 42.277 58.094 1.00 71.99 C +ATOM 23217 O GLN M 47 38.464 41.646 58.346 1.00 46.93 O +ATOM 23218 CB GLN M 47 36.045 42.635 60.126 1.00 75.95 C +ATOM 23219 CG GLN M 47 34.636 42.631 60.677 1.00106.09 C +ATOM 23220 CD GLN M 47 33.611 43.167 59.691 1.00141.51 C +ATOM 23221 OE1 GLN M 47 33.534 44.361 59.453 1.00144.69 O +ATOM 23222 NE2 GLN M 47 32.779 42.288 59.158 1.00181.00 N +ATOM 23223 N PHE M 48 37.385 43.260 57.205 1.00 86.27 N +ATOM 23224 CA PHE M 48 38.535 43.741 56.486 1.00 77.76 C +ATOM 23225 C PHE M 48 38.692 45.240 56.701 1.00 84.56 C +ATOM 23226 O PHE M 48 37.784 45.951 57.154 1.00 81.98 O +ATOM 23227 CB PHE M 48 38.375 43.461 54.992 1.00 81.39 C +ATOM 23228 CG PHE M 48 38.369 42.031 54.669 1.00 72.93 C +ATOM 23229 CD1 PHE M 48 37.211 41.293 54.856 1.00 76.99 C +ATOM 23230 CD2 PHE M 48 39.491 41.427 54.202 1.00 61.42 C +ATOM 23231 CE1 PHE M 48 37.188 39.948 54.613 1.00 82.61 C +ATOM 23232 CE2 PHE M 48 39.469 40.087 53.926 1.00 75.55 C +ATOM 23233 CZ PHE M 48 38.325 39.343 54.133 1.00 82.17 C +ATOM 23234 N LYS M 49 39.847 45.724 56.287 1.00 92.76 N +ATOM 23235 CA LYS M 49 40.171 47.119 56.452 1.00 91.39 C +ATOM 23236 C LYS M 49 39.443 47.937 55.393 1.00 91.97 C +ATOM 23237 O LYS M 49 39.260 47.485 54.267 1.00 87.87 O +ATOM 23238 CB LYS M 49 41.696 47.321 56.405 1.00 89.01 C +ATOM 23239 CG LYS M 49 42.411 46.646 57.576 1.00 92.18 C +ATOM 23240 CD LYS M 49 43.884 46.951 57.755 1.00 91.05 C +ATOM 23241 CE LYS M 49 44.315 46.325 59.086 1.00 86.56 C +ATOM 23242 NZ LYS M 49 45.732 46.562 59.467 1.00109.12 N +ATOM 23243 N PRO M 50 39.031 49.152 55.766 1.00108.84 N +ATOM 23244 CA PRO M 50 38.382 50.071 54.847 1.00108.56 C +ATOM 23245 C PRO M 50 39.365 50.783 53.906 1.00 80.09 C +ATOM 23246 O PRO M 50 40.596 50.708 54.105 1.00 57.75 O +ATOM 23247 CB PRO M 50 37.722 51.081 55.789 1.00120.36 C +ATOM 23248 CG PRO M 50 38.591 51.099 57.001 1.00113.78 C +ATOM 23249 CD PRO M 50 39.143 49.709 57.131 1.00115.41 C +ATOM 23250 N TYR M 51 38.816 51.471 52.908 1.00 50.35 N +ATOM 23251 CA TYR M 51 39.632 52.279 52.056 1.00 49.38 C +ATOM 23252 C TYR M 51 40.454 53.187 52.931 1.00 47.45 C +ATOM 23253 O TYR M 51 39.926 53.772 53.880 1.00 42.75 O +ATOM 23254 CB TYR M 51 38.768 53.100 51.097 1.00 59.68 C +ATOM 23255 CG TYR M 51 39.597 53.717 49.984 1.00 68.63 C +ATOM 23256 CD1 TYR M 51 39.858 52.998 48.825 1.00 70.44 C +ATOM 23257 CD2 TYR M 51 40.142 54.998 50.098 1.00 75.71 C +ATOM 23258 CE1 TYR M 51 40.664 53.499 47.824 1.00 79.53 C +ATOM 23259 CE2 TYR M 51 40.931 55.534 49.076 1.00 87.88 C +ATOM 23260 CZ TYR M 51 41.222 54.749 47.958 1.00 98.28 C +ATOM 23261 OH TYR M 51 42.010 55.200 46.912 1.00101.93 O +ATOM 23262 N PRO M 52 41.755 53.357 52.617 1.00 59.80 N +ATOM 23263 CA PRO M 52 42.501 52.921 51.438 1.00 69.46 C +ATOM 23264 C PRO M 52 43.247 51.609 51.534 1.00 79.97 C +ATOM 23265 O PRO M 52 44.130 51.359 50.703 1.00 70.20 O +ATOM 23266 CB PRO M 52 43.532 54.032 51.258 1.00 82.52 C +ATOM 23267 CG PRO M 52 43.844 54.453 52.657 1.00 88.55 C +ATOM 23268 CD PRO M 52 42.553 54.303 53.431 1.00 78.22 C +ATOM 23269 N ALA M 53 42.867 50.747 52.473 1.00 89.99 N +ATOM 23270 CA ALA M 53 43.516 49.443 52.561 1.00 93.10 C +ATOM 23271 C ALA M 53 43.147 48.591 51.375 1.00 78.04 C +ATOM 23272 O ALA M 53 42.162 48.863 50.647 1.00 67.58 O +ATOM 23273 CB ALA M 53 43.121 48.725 53.823 1.00116.02 C +ATOM 23274 N SER M 54 43.977 47.583 51.123 1.00 66.39 N +ATOM 23275 CA SER M 54 43.591 46.601 50.116 1.00 55.07 C +ATOM 23276 C SER M 54 42.244 46.014 50.540 1.00 43.41 C +ATOM 23277 O SER M 54 42.018 45.752 51.722 1.00 40.39 O +ATOM 23278 CB SER M 54 44.668 45.511 49.917 1.00 45.04 C +ATOM 23279 OG SER M 54 44.123 44.317 49.352 1.00 30.01 O +ATOM 23280 N ASN M 55 41.410 45.752 49.545 1.00 36.21 N +ATOM 23281 CA ASN M 55 40.193 45.022 49.736 1.00 39.29 C +ATOM 23282 C ASN M 55 40.360 43.763 50.589 1.00 43.63 C +ATOM 23283 O ASN M 55 39.479 43.337 51.330 1.00 35.53 O +ATOM 23284 CB ASN M 55 39.659 44.622 48.379 1.00 40.96 C +ATOM 23285 CG ASN M 55 38.249 44.143 48.459 1.00 67.90 C +ATOM 23286 OD1 ASN M 55 37.487 44.497 49.372 1.00109.68 O +ATOM 23287 ND2 ASN M 55 37.821 43.510 47.404 1.00 96.44 N +ATOM 23288 N PHE M 56 41.538 43.166 50.482 1.00 57.10 N +ATOM 23289 CA PHE M 56 41.795 41.856 51.055 1.00 54.68 C +ATOM 23290 C PHE M 56 42.492 41.919 52.404 1.00 67.36 C +ATOM 23291 O PHE M 56 42.912 40.881 52.933 1.00 77.59 O +ATOM 23292 CB PHE M 56 42.685 41.050 50.118 1.00 55.36 C +ATOM 23293 CG PHE M 56 42.101 40.849 48.765 1.00 46.36 C +ATOM 23294 CD1 PHE M 56 40.897 40.189 48.584 1.00 37.54 C +ATOM 23295 CD2 PHE M 56 42.788 41.293 47.667 1.00 56.26 C +ATOM 23296 CE1 PHE M 56 40.379 39.986 47.328 1.00 39.16 C +ATOM 23297 CE2 PHE M 56 42.294 41.047 46.392 1.00 61.02 C +ATOM 23298 CZ PHE M 56 41.078 40.402 46.223 1.00 44.98 C +ATOM 23299 N SER M 57 42.788 43.120 52.890 1.00 69.28 N +ATOM 23300 CA SER M 57 43.542 43.236 54.145 1.00 71.60 C +ATOM 23301 C SER M 57 42.564 42.964 55.272 1.00 81.34 C +ATOM 23302 O SER M 57 41.601 43.691 55.467 1.00 70.49 O +ATOM 23303 CB SER M 57 44.208 44.615 54.297 1.00 66.12 C +ATOM 23304 OG SER M 57 45.354 44.704 53.466 1.00 66.40 O +ATOM 23305 N THR M 58 42.814 41.888 56.010 1.00 89.82 N +ATOM 23306 CA THR M 58 41.950 41.515 57.110 1.00 65.51 C +ATOM 23307 C THR M 58 42.143 42.457 58.266 1.00 68.51 C +ATOM 23308 O THR M 58 43.186 43.043 58.479 1.00 40.14 O +ATOM 23309 CB THR M 58 42.288 40.130 57.628 1.00 49.28 C +ATOM 23310 OG1 THR M 58 43.635 40.101 58.088 1.00 34.66 O +ATOM 23311 CG2 THR M 58 42.147 39.163 56.534 1.00 56.42 C +ATOM 23312 N ALA M 59 41.104 42.625 59.032 1.00 92.19 N +ATOM 23313 CA ALA M 59 41.218 43.587 60.097 1.00 99.71 C +ATOM 23314 C ALA M 59 42.064 43.019 61.233 1.00 79.74 C +ATOM 23315 O ALA M 59 42.528 43.746 62.092 1.00 85.86 O +ATOM 23316 CB ALA M 59 39.837 43.995 60.573 1.00124.90 C +ATOM 23317 N VAL M 60 42.179 41.696 61.271 1.00 71.68 N +ATOM 23318 CA VAL M 60 42.754 40.983 62.407 1.00 63.94 C +ATOM 23319 C VAL M 60 43.749 39.972 61.848 1.00 63.30 C +ATOM 23320 O VAL M 60 43.470 39.309 60.851 1.00 88.47 O +ATOM 23321 CB VAL M 60 41.650 40.233 63.193 1.00 65.63 C +ATOM 23322 CG1 VAL M 60 42.231 39.457 64.360 1.00 70.05 C +ATOM 23323 CG2 VAL M 60 40.602 41.204 63.689 1.00 85.04 C +ATOM 23324 N PRO M 61 44.912 39.850 62.476 1.00 52.15 N +ATOM 23325 CA PRO M 61 45.845 38.855 61.995 1.00 54.57 C +ATOM 23326 C PRO M 61 45.306 37.441 62.060 1.00 59.21 C +ATOM 23327 O PRO M 61 44.631 37.062 63.059 1.00 97.99 O +ATOM 23328 CB PRO M 61 47.060 39.032 62.938 1.00 62.70 C +ATOM 23329 CG PRO M 61 46.524 39.691 64.165 1.00 52.51 C +ATOM 23330 CD PRO M 61 45.418 40.574 63.657 1.00 54.46 C +ATOM 23331 N GLN M 62 45.707 36.632 61.082 1.00 57.33 N +ATOM 23332 CA GLN M 62 45.254 35.245 60.998 1.00 64.10 C +ATOM 23333 C GLN M 62 46.123 34.308 61.798 1.00 61.69 C +ATOM 23334 O GLN M 62 46.320 33.166 61.410 1.00 53.48 O +ATOM 23335 CB GLN M 62 45.276 34.786 59.547 1.00 82.04 C +ATOM 23336 CG GLN M 62 44.584 35.751 58.601 1.00106.91 C +ATOM 23337 CD GLN M 62 43.134 35.985 58.992 1.00111.47 C +ATOM 23338 OE1 GLN M 62 42.263 35.168 58.708 1.00101.16 O +ATOM 23339 NE2 GLN M 62 42.874 37.099 59.649 1.00110.97 N +ATOM 23340 N SER M 63 46.626 34.782 62.941 1.00 77.87 N +ATOM 23341 CA SER M 63 47.749 34.135 63.636 1.00 75.86 C +ATOM 23342 C SER M 63 47.383 33.752 65.079 1.00 93.81 C +ATOM 23343 O SER M 63 48.218 33.233 65.824 1.00101.69 O +ATOM 23344 CB SER M 63 48.966 35.065 63.635 1.00 53.71 C +ATOM 23345 OG SER M 63 48.700 36.249 64.348 1.00 41.33 O +ATOM 23346 N ALA M 64 46.092 33.838 65.397 1.00112.93 N +ATOM 23347 CA ALA M 64 45.598 33.518 66.729 1.00127.63 C +ATOM 23348 C ALA M 64 46.026 32.129 67.274 1.00158.70 C +ATOM 23349 O ALA M 64 46.341 31.973 68.467 1.00164.30 O +ATOM 23350 CB ALA M 64 44.081 33.644 66.748 1.00144.19 C +ATOM 23351 N THR M 65 45.989 31.118 66.407 1.00153.76 N +ATOM 23352 CA THR M 65 46.311 29.735 66.775 1.00119.26 C +ATOM 23353 C THR M 65 47.669 29.636 67.445 1.00101.15 C +ATOM 23354 O THR M 65 47.803 29.047 68.518 1.00102.88 O +ATOM 23355 CB THR M 65 46.365 28.867 65.519 1.00107.66 C +ATOM 23356 OG1 THR M 65 45.305 29.263 64.646 1.00112.10 O +ATOM 23357 CG2 THR M 65 46.245 27.390 65.879 1.00103.42 C +ATOM 23358 N ALA M 66 48.665 30.241 66.814 1.00 93.26 N +ATOM 23359 CA ALA M 66 50.007 30.174 67.325 1.00 88.45 C +ATOM 23360 C ALA M 66 50.167 30.984 68.625 1.00 68.31 C +ATOM 23361 O ALA M 66 50.914 30.569 69.535 1.00 54.24 O +ATOM 23362 CB ALA M 66 50.975 30.652 66.265 1.00105.04 C +ATOM 23363 N MET M 67 49.455 32.108 68.708 1.00 52.02 N +ATOM 23364 CA MET M 67 49.460 32.917 69.916 1.00 63.07 C +ATOM 23365 C MET M 67 48.864 32.129 71.085 1.00 62.54 C +ATOM 23366 O MET M 67 49.405 32.165 72.226 1.00 68.28 O +ATOM 23367 CB MET M 67 48.644 34.190 69.731 1.00 84.80 C +ATOM 23368 CG MET M 67 49.244 35.233 68.792 1.00 75.96 C +ATOM 23369 SD MET M 67 48.014 36.523 68.388 1.00 93.70 S +ATOM 23370 CE MET M 67 49.025 37.676 67.469 1.00 92.41 C +ATOM 23371 N LEU M 68 47.775 31.394 70.817 1.00 45.26 N +ATOM 23372 CA LEU M 68 47.182 30.584 71.861 1.00 53.27 C +ATOM 23373 C LEU M 68 48.144 29.476 72.346 1.00 66.18 C +ATOM 23374 O LEU M 68 48.264 29.245 73.559 1.00 77.92 O +ATOM 23375 CB LEU M 68 45.888 29.943 71.419 1.00 52.53 C +ATOM 23376 CG LEU M 68 45.318 28.903 72.423 1.00 65.77 C +ATOM 23377 CD1 LEU M 68 44.887 29.567 73.737 1.00 62.36 C +ATOM 23378 CD2 LEU M 68 44.158 28.095 71.847 1.00 63.82 C +ATOM 23379 N VAL M 69 48.781 28.775 71.417 1.00 62.73 N +ATOM 23380 CA VAL M 69 49.698 27.697 71.775 1.00 51.73 C +ATOM 23381 C VAL M 69 50.813 28.269 72.593 1.00 52.82 C +ATOM 23382 O VAL M 69 51.213 27.699 73.631 1.00 77.73 O +ATOM 23383 CB VAL M 69 50.314 27.026 70.543 1.00 62.02 C +ATOM 23384 CG1 VAL M 69 51.401 26.068 70.958 1.00 57.99 C +ATOM 23385 CG2 VAL M 69 49.254 26.272 69.730 1.00 68.16 C +ATOM 23386 N THR M 70 51.318 29.417 72.161 1.00 50.89 N +ATOM 23387 CA THR M 70 52.371 30.103 72.922 1.00 77.72 C +ATOM 23388 C THR M 70 51.961 30.545 74.352 1.00 57.83 C +ATOM 23389 O THR M 70 52.690 30.283 75.329 1.00 48.90 O +ATOM 23390 CB THR M 70 52.885 31.323 72.156 1.00 95.24 C +ATOM 23391 OG1 THR M 70 53.279 30.905 70.840 1.00 89.83 O +ATOM 23392 CG2 THR M 70 54.098 31.983 72.890 1.00 89.55 C +ATOM 23393 N ALA M 71 50.789 31.141 74.465 1.00 45.34 N +ATOM 23394 CA ALA M 71 50.250 31.455 75.774 1.00 52.54 C +ATOM 23395 C ALA M 71 50.028 30.212 76.665 1.00 57.22 C +ATOM 23396 O ALA M 71 50.377 30.224 77.861 1.00 62.11 O +ATOM 23397 CB ALA M 71 48.939 32.184 75.623 1.00 68.84 C +ATOM 23398 N LEU M 72 49.468 29.145 76.088 1.00 54.78 N +ATOM 23399 CA LEU M 72 49.365 27.861 76.797 1.00 61.36 C +ATOM 23400 C LEU M 72 50.712 27.294 77.277 1.00 74.51 C +ATOM 23401 O LEU M 72 50.774 26.609 78.309 1.00 90.83 O +ATOM 23402 CB LEU M 72 48.725 26.795 75.925 1.00 56.76 C +ATOM 23403 CG LEU M 72 47.291 27.080 75.572 1.00 52.65 C +ATOM 23404 CD1 LEU M 72 46.906 26.205 74.408 1.00 64.53 C +ATOM 23405 CD2 LEU M 72 46.363 26.808 76.729 1.00 64.17 C +ATOM 23406 N LYS M 73 51.796 27.613 76.573 1.00 74.30 N +ATOM 23407 CA LYS M 73 53.116 27.201 77.022 1.00 89.25 C +ATOM 23408 C LYS M 73 53.711 28.112 78.108 1.00118.20 C +ATOM 23409 O LYS M 73 54.259 27.623 79.103 1.00126.27 O +ATOM 23410 CB LYS M 73 54.076 27.154 75.860 1.00 83.87 C +ATOM 23411 CG LYS M 73 55.371 26.467 76.213 1.00 98.45 C +ATOM 23412 CD LYS M 73 56.477 26.991 75.343 1.00106.37 C +ATOM 23413 CE LYS M 73 57.051 28.356 75.803 1.00115.55 C +ATOM 23414 NZ LYS M 73 58.383 28.221 76.458 1.00118.40 N +ATOM 23415 N ASP M 74 53.627 29.429 77.903 1.00128.38 N +ATOM 23416 CA ASP M 74 54.206 30.408 78.838 1.00124.70 C +ATOM 23417 C ASP M 74 53.596 30.310 80.243 1.00123.99 C +ATOM 23418 O ASP M 74 54.280 30.574 81.233 1.00139.48 O +ATOM 23419 CB ASP M 74 54.013 31.830 78.321 1.00134.56 C +ATOM 23420 CG ASP M 74 54.831 32.126 77.063 1.00162.24 C +ATOM 23421 OD1 ASP M 74 55.918 31.529 76.861 1.00155.21 O +ATOM 23422 OD2 ASP M 74 54.386 33.003 76.286 1.00187.68 O +ATOM 23423 N SER M 75 52.346 29.843 80.324 1.00108.32 N +ATOM 23424 CA SER M 75 51.637 29.683 81.605 1.00 86.94 C +ATOM 23425 C SER M 75 52.270 28.646 82.533 1.00 85.13 C +ATOM 23426 O SER M 75 52.114 28.728 83.750 1.00 91.39 O +ATOM 23427 CB SER M 75 50.183 29.277 81.366 1.00 87.35 C +ATOM 23428 OG SER M 75 50.047 27.865 81.243 1.00 69.05 O +ATOM 23429 N ARG M 76 52.964 27.668 81.942 1.00 84.99 N +ATOM 23430 CA ARG M 76 53.626 26.581 82.664 1.00 91.04 C +ATOM 23431 C ARG M 76 52.620 25.684 83.333 1.00 84.32 C +ATOM 23432 O ARG M 76 52.826 25.219 84.464 1.00155.66 O +ATOM 23433 CB ARG M 76 54.650 27.120 83.677 1.00117.61 C +ATOM 23434 CG ARG M 76 55.819 27.908 83.076 1.00142.23 C +ATOM 23435 CD ARG M 76 56.797 28.353 84.168 1.00143.36 C +ATOM 23436 NE ARG M 76 56.223 29.375 85.049 1.00150.87 N +ATOM 23437 CZ ARG M 76 55.577 29.141 86.197 1.00126.67 C +ATOM 23438 NH1 ARG M 76 55.433 27.908 86.676 1.00123.46 N +ATOM 23439 NH2 ARG M 76 55.077 30.158 86.874 1.00 97.92 N +ATOM 23440 N TRP M 77 51.494 25.531 82.669 1.00 67.31 N +ATOM 23441 CA TRP M 77 50.472 24.608 83.096 1.00 76.66 C +ATOM 23442 C TRP M 77 50.320 23.496 82.057 1.00 86.55 C +ATOM 23443 O TRP M 77 49.991 22.361 82.392 1.00 90.60 O +ATOM 23444 CB TRP M 77 49.141 25.357 83.265 1.00 88.92 C +ATOM 23445 CG TRP M 77 48.886 25.829 84.657 1.00 99.65 C +ATOM 23446 CD1 TRP M 77 49.436 26.911 85.261 1.00107.90 C +ATOM 23447 CD2 TRP M 77 47.981 25.250 85.613 1.00110.65 C +ATOM 23448 NE1 TRP M 77 48.950 27.040 86.539 1.00107.54 N +ATOM 23449 CE2 TRP M 77 48.061 26.027 86.780 1.00 96.64 C +ATOM 23450 CE3 TRP M 77 47.113 24.151 85.591 1.00110.98 C +ATOM 23451 CZ2 TRP M 77 47.321 25.738 87.913 1.00 97.71 C +ATOM 23452 CZ3 TRP M 77 46.360 23.884 86.707 1.00102.48 C +ATOM 23453 CH2 TRP M 77 46.470 24.673 87.857 1.00107.02 C +ATOM 23454 N PHE M 78 50.512 23.856 80.786 1.00 93.61 N +ATOM 23455 CA PHE M 78 50.244 22.972 79.644 1.00 71.70 C +ATOM 23456 C PHE M 78 51.492 22.713 78.796 1.00 75.58 C +ATOM 23457 O PHE M 78 52.329 23.622 78.583 1.00 85.64 O +ATOM 23458 CB PHE M 78 49.220 23.608 78.720 1.00 72.80 C +ATOM 23459 CG PHE M 78 47.942 23.981 79.390 1.00 79.71 C +ATOM 23460 CD1 PHE M 78 47.015 23.007 79.737 1.00 97.48 C +ATOM 23461 CD2 PHE M 78 47.648 25.296 79.644 1.00 67.01 C +ATOM 23462 CE1 PHE M 78 45.818 23.346 80.329 1.00 93.44 C +ATOM 23463 CE2 PHE M 78 46.463 25.640 80.258 1.00 76.55 C +ATOM 23464 CZ PHE M 78 45.538 24.671 80.582 1.00 86.17 C +ATOM 23465 N ILE M 79 51.592 21.486 78.288 1.00 69.95 N +ATOM 23466 CA ILE M 79 52.526 21.141 77.223 1.00 72.79 C +ATOM 23467 C ILE M 79 51.701 21.121 75.942 1.00 72.45 C +ATOM 23468 O ILE M 79 50.675 20.437 75.903 1.00 58.88 O +ATOM 23469 CB ILE M 79 53.116 19.740 77.414 1.00 74.94 C +ATOM 23470 CG1 ILE M 79 53.681 19.570 78.821 1.00 82.34 C +ATOM 23471 CG2 ILE M 79 54.215 19.467 76.386 1.00 81.52 C +ATOM 23472 CD1 ILE M 79 53.757 18.114 79.272 1.00101.24 C +ATOM 23473 N PRO M 80 52.113 21.919 74.922 1.00 63.64 N +ATOM 23474 CA PRO M 80 51.309 21.898 73.728 1.00 57.87 C +ATOM 23475 C PRO M 80 51.841 20.911 72.752 1.00 56.67 C +ATOM 23476 O PRO M 80 53.059 20.797 72.617 1.00 81.37 O +ATOM 23477 CB PRO M 80 51.467 23.295 73.182 1.00 56.03 C +ATOM 23478 CG PRO M 80 51.803 24.133 74.351 1.00 64.18 C +ATOM 23479 CD PRO M 80 52.730 23.243 75.113 1.00 66.40 C +ATOM 23480 N LEU M 81 50.955 20.068 72.248 1.00 43.89 N +ATOM 23481 CA LEU M 81 51.332 19.132 71.269 1.00 53.97 C +ATOM 23482 C LEU M 81 51.079 19.749 69.913 1.00 92.38 C +ATOM 23483 O LEU M 81 50.079 20.491 69.722 1.00 82.97 O +ATOM 23484 CB LEU M 81 50.551 17.860 71.438 1.00 53.83 C +ATOM 23485 CG LEU M 81 50.736 17.288 72.823 1.00 48.74 C +ATOM 23486 CD1 LEU M 81 49.856 16.068 72.970 1.00 55.57 C +ATOM 23487 CD2 LEU M 81 52.170 16.896 73.039 1.00 58.81 C +ATOM 23488 N GLU M 82 52.018 19.478 68.989 1.00119.99 N +ATOM 23489 CA GLU M 82 52.009 20.086 67.659 1.00113.54 C +ATOM 23490 C GLU M 82 50.991 19.397 66.758 1.00 84.50 C +ATOM 23491 O GLU M 82 51.210 18.279 66.288 1.00 43.78 O +ATOM 23492 CB GLU M 82 53.408 20.113 67.010 1.00 90.75 C +ATOM 23493 CG GLU M 82 53.451 20.752 65.622 1.00102.61 C +ATOM 23494 CD GLU M 82 53.244 22.287 65.611 1.00110.30 C +ATOM 23495 OE1 GLU M 82 52.261 22.828 66.193 1.00120.26 O +ATOM 23496 OE2 GLU M 82 54.012 22.976 64.902 1.00136.63 O +ATOM 23497 N ARG M 83 49.894 20.129 66.505 1.00 85.76 N +ATOM 23498 CA ARG M 83 48.894 19.737 65.532 1.00 82.58 C +ATOM 23499 C ARG M 83 48.657 20.771 64.403 1.00 77.02 C +ATOM 23500 O ARG M 83 48.150 20.404 63.330 1.00 57.12 O +ATOM 23501 CB ARG M 83 47.590 19.437 66.241 1.00 81.88 C +ATOM 23502 CG ARG M 83 47.727 18.393 67.350 1.00 81.39 C +ATOM 23503 CD ARG M 83 48.006 16.973 66.812 1.00 63.49 C +ATOM 23504 NE ARG M 83 47.851 15.976 67.853 1.00 57.49 N +ATOM 23505 CZ ARG M 83 48.831 15.518 68.611 1.00 76.72 C +ATOM 23506 NH1 ARG M 83 50.100 15.769 68.306 1.00 99.17 N +ATOM 23507 NH2 ARG M 83 48.541 14.778 69.680 1.00 93.99 N +ATOM 23508 N GLN M 84 49.076 22.020 64.580 1.00 68.98 N +ATOM 23509 CA GLN M 84 48.881 22.962 63.489 1.00 84.35 C +ATOM 23510 C GLN M 84 49.621 22.453 62.247 1.00 94.08 C +ATOM 23511 O GLN M 84 49.126 22.566 61.133 1.00109.30 O +ATOM 23512 CB GLN M 84 49.290 24.394 63.865 1.00 97.23 C +ATOM 23513 CG GLN M 84 48.477 25.499 63.157 1.00 94.02 C +ATOM 23514 CD GLN M 84 48.957 26.912 63.496 1.00129.33 C +ATOM 23515 OE1 GLN M 84 49.416 27.172 64.604 1.00167.61 O +ATOM 23516 NE2 GLN M 84 48.920 27.804 62.515 1.00146.33 N +ATOM 23517 N GLY M 85 50.830 21.945 62.417 1.00 85.11 N +ATOM 23518 CA GLY M 85 51.579 21.493 61.252 1.00 90.49 C +ATOM 23519 C GLY M 85 51.681 19.989 61.176 1.00 82.00 C +ATOM 23520 O GLY M 85 52.752 19.453 60.874 1.00 61.61 O +ATOM 23521 N LEU M 86 50.581 19.293 61.461 1.00 79.21 N +ATOM 23522 CA LEU M 86 50.657 17.844 61.787 1.00 79.73 C +ATOM 23523 C LEU M 86 51.121 17.075 60.581 1.00 90.07 C +ATOM 23524 O LEU M 86 51.869 16.096 60.705 1.00113.57 O +ATOM 23525 CB LEU M 86 49.299 17.310 62.243 1.00 53.11 C +ATOM 23526 CG LEU M 86 49.103 15.823 62.394 1.00 44.54 C +ATOM 23527 CD1 LEU M 86 50.026 15.194 63.424 1.00 38.48 C +ATOM 23528 CD2 LEU M 86 47.653 15.546 62.781 1.00 62.70 C +ATOM 23529 N GLN M 87 50.765 17.578 59.406 1.00 90.91 N +ATOM 23530 CA GLN M 87 51.084 16.869 58.170 1.00105.20 C +ATOM 23531 C GLN M 87 52.614 16.724 57.956 1.00108.70 C +ATOM 23532 O GLN M 87 53.128 15.645 57.608 1.00 88.67 O +ATOM 23533 CB GLN M 87 50.405 17.565 56.987 1.00110.01 C +ATOM 23534 CG GLN M 87 49.951 16.606 55.889 1.00108.36 C +ATOM 23535 CD GLN M 87 49.289 15.337 56.423 1.00106.90 C +ATOM 23536 OE1 GLN M 87 48.293 15.399 57.156 1.00123.19 O +ATOM 23537 NE2 GLN M 87 49.845 14.178 56.071 1.00 97.76 N +ATOM 23538 N ASN M 88 53.340 17.804 58.234 1.00103.71 N +ATOM 23539 CA ASN M 88 54.794 17.812 58.106 1.00 89.01 C +ATOM 23540 C ASN M 88 55.449 16.902 59.127 1.00 90.12 C +ATOM 23541 O ASN M 88 56.481 16.260 58.834 1.00138.26 O +ATOM 23542 CB ASN M 88 55.337 19.213 58.332 1.00 84.19 C +ATOM 23543 CG ASN M 88 54.749 20.218 57.383 1.00 84.80 C +ATOM 23544 OD1 ASN M 88 54.502 19.907 56.230 1.00 73.49 O +ATOM 23545 ND2 ASN M 88 54.461 21.423 57.888 1.00 97.63 N +ATOM 23546 N LEU M 89 54.873 16.873 60.322 1.00 52.50 N +ATOM 23547 CA LEU M 89 55.380 16.034 61.353 1.00 60.34 C +ATOM 23548 C LEU M 89 55.309 14.563 60.912 1.00 69.65 C +ATOM 23549 O LEU M 89 56.252 13.765 61.073 1.00115.26 O +ATOM 23550 CB LEU M 89 54.550 16.273 62.605 1.00 70.95 C +ATOM 23551 CG LEU M 89 55.214 16.081 63.981 1.00 72.67 C +ATOM 23552 CD1 LEU M 89 54.548 14.953 64.734 1.00 62.85 C +ATOM 23553 CD2 LEU M 89 56.718 15.824 63.889 1.00 53.02 C +ATOM 23554 N LEU M 90 54.196 14.204 60.301 1.00 67.47 N +ATOM 23555 CA LEU M 90 53.984 12.825 59.872 1.00 66.37 C +ATOM 23556 C LEU M 90 54.918 12.466 58.709 1.00 73.01 C +ATOM 23557 O LEU M 90 55.306 11.298 58.526 1.00 58.89 O +ATOM 23558 CB LEU M 90 52.512 12.621 59.476 1.00 49.75 C +ATOM 23559 CG LEU M 90 51.531 12.865 60.608 1.00 39.10 C +ATOM 23560 CD1 LEU M 90 50.159 13.084 60.028 1.00 48.45 C +ATOM 23561 CD2 LEU M 90 51.532 11.697 61.565 1.00 38.28 C +ATOM 23562 N ASN M 91 55.208 13.471 57.894 1.00 86.89 N +ATOM 23563 CA ASN M 91 56.081 13.297 56.759 1.00101.79 C +ATOM 23564 C ASN M 91 57.510 13.030 57.218 1.00 97.42 C +ATOM 23565 O ASN M 91 58.162 12.085 56.739 1.00122.79 O +ATOM 23566 CB ASN M 91 56.029 14.556 55.906 1.00106.53 C +ATOM 23567 CG ASN M 91 55.521 14.324 54.515 1.00137.72 C +ATOM 23568 OD1 ASN M 91 54.800 13.359 54.221 1.00122.04 O +ATOM 23569 ND2 ASN M 91 55.883 15.250 53.637 1.00172.41 N +ATOM 23570 N GLU M 92 58.007 13.850 58.135 1.00 74.04 N +ATOM 23571 CA GLU M 92 59.342 13.614 58.690 1.00 76.54 C +ATOM 23572 C GLU M 92 59.433 12.202 59.283 1.00 70.98 C +ATOM 23573 O GLU M 92 60.496 11.563 59.236 1.00 63.65 O +ATOM 23574 CB GLU M 92 59.717 14.676 59.743 1.00 71.88 C +ATOM 23575 CG GLU M 92 60.466 15.863 59.172 1.00 87.15 C +ATOM 23576 CD GLU M 92 61.725 15.472 58.361 1.00 80.10 C +ATOM 23577 OE1 GLU M 92 62.648 14.814 58.878 1.00 57.30 O +ATOM 23578 OE2 GLU M 92 61.830 15.877 57.183 1.00 67.66 O +ATOM 23579 N ARG M 93 58.333 11.738 59.877 1.00 61.01 N +ATOM 23580 CA ARG M 93 58.331 10.438 60.525 1.00 67.25 C +ATOM 23581 C ARG M 93 58.349 9.338 59.472 1.00 96.12 C +ATOM 23582 O ARG M 93 59.002 8.307 59.659 1.00122.91 O +ATOM 23583 CB ARG M 93 57.149 10.330 61.478 1.00 63.26 C +ATOM 23584 CG ARG M 93 57.333 11.204 62.704 1.00 99.19 C +ATOM 23585 CD ARG M 93 56.078 11.424 63.532 1.00111.80 C +ATOM 23586 NE ARG M 93 56.059 10.576 64.721 1.00111.24 N +ATOM 23587 CZ ARG M 93 55.491 9.383 64.784 1.00105.49 C +ATOM 23588 NH1 ARG M 93 54.780 8.895 63.753 1.00103.03 N +ATOM 23589 NH2 ARG M 93 55.568 8.723 65.927 1.00 82.53 N +ATOM 23590 N LYS M 94 57.729 9.591 58.318 1.00 93.39 N +ATOM 23591 CA LYS M 94 57.846 8.660 57.185 1.00 74.81 C +ATOM 23592 C LYS M 94 59.299 8.565 56.713 1.00 79.47 C +ATOM 23593 O LYS M 94 59.799 7.468 56.421 1.00 66.35 O +ATOM 23594 CB LYS M 94 57.005 9.131 56.019 1.00 85.55 C +ATOM 23595 CG LYS M 94 55.565 8.668 56.022 1.00117.26 C +ATOM 23596 CD LYS M 94 54.791 9.366 54.905 1.00132.92 C +ATOM 23597 CE LYS M 94 53.517 8.631 54.518 1.00134.54 C +ATOM 23598 NZ LYS M 94 52.641 9.517 53.701 1.00144.68 N +ATOM 23599 N ILE M 95 59.989 9.711 56.670 1.00 79.73 N +ATOM 23600 CA ILE M 95 61.356 9.742 56.152 1.00 83.59 C +ATOM 23601 C ILE M 95 62.332 9.082 57.104 1.00 79.74 C +ATOM 23602 O ILE M 95 63.256 8.359 56.649 1.00 86.31 O +ATOM 23603 CB ILE M 95 61.880 11.160 55.884 1.00 90.85 C +ATOM 23604 CG1 ILE M 95 60.858 11.987 55.092 1.00 87.70 C +ATOM 23605 CG2 ILE M 95 63.166 11.049 55.077 1.00104.10 C +ATOM 23606 CD1 ILE M 95 61.410 13.275 54.502 1.00 93.75 C +ATOM 23607 N ILE M 96 62.116 9.337 58.408 1.00 57.03 N +ATOM 23608 CA ILE M 96 62.843 8.652 59.465 1.00 41.70 C +ATOM 23609 C ILE M 96 62.694 7.146 59.306 1.00 52.65 C +ATOM 23610 O ILE M 96 63.682 6.427 59.129 1.00 55.00 O +ATOM 23611 CB ILE M 96 62.364 9.031 60.834 1.00 29.72 C +ATOM 23612 CG1 ILE M 96 62.700 10.455 61.126 1.00 29.07 C +ATOM 23613 CG2 ILE M 96 63.067 8.179 61.854 1.00 26.90 C +ATOM 23614 CD1 ILE M 96 62.313 10.892 62.529 1.00 34.92 C +ATOM 23615 N ARG M 97 61.451 6.662 59.294 1.00 53.84 N +ATOM 23616 CA ARG M 97 61.200 5.204 59.244 1.00 67.38 C +ATOM 23617 C ARG M 97 61.761 4.563 57.965 1.00 63.48 C +ATOM 23618 O ARG M 97 62.185 3.402 57.968 1.00 49.97 O +ATOM 23619 CB ARG M 97 59.696 4.892 59.363 1.00 88.78 C +ATOM 23620 CG ARG M 97 59.233 4.387 60.737 1.00 67.38 C +ATOM 23621 CD ARG M 97 57.750 4.049 60.715 1.00 69.65 C +ATOM 23622 NE ARG M 97 56.896 5.230 60.856 1.00 71.49 N +ATOM 23623 CZ ARG M 97 56.336 5.631 61.999 1.00 88.51 C +ATOM 23624 NH1 ARG M 97 56.489 4.919 63.122 1.00 66.34 N +ATOM 23625 NH2 ARG M 97 55.600 6.754 62.014 1.00101.70 N +ATOM 23626 N ALA M 98 61.783 5.332 56.886 1.00 65.52 N +ATOM 23627 CA ALA M 98 62.343 4.844 55.643 1.00 91.43 C +ATOM 23628 C ALA M 98 63.874 4.802 55.707 1.00 95.36 C +ATOM 23629 O ALA M 98 64.514 3.983 55.032 1.00 58.29 O +ATOM 23630 CB ALA M 98 61.879 5.727 54.503 1.00126.72 C +ATOM 23631 N ALA M 99 64.440 5.685 56.538 1.00118.81 N +ATOM 23632 CA ALA M 99 65.895 5.794 56.703 1.00113.97 C +ATOM 23633 C ALA M 99 66.474 4.603 57.432 1.00 99.82 C +ATOM 23634 O ALA M 99 67.426 3.973 56.974 1.00 99.06 O +ATOM 23635 CB ALA M 99 66.255 7.067 57.451 1.00113.23 C +ATOM 23636 N GLN M 100 65.867 4.278 58.561 1.00113.26 N +ATOM 23637 CA GLN M 100 66.499 3.377 59.521 1.00124.20 C +ATOM 23638 C GLN M 100 65.876 1.984 59.571 1.00 99.68 C +ATOM 23639 O GLN M 100 66.263 1.161 60.417 1.00130.10 O +ATOM 23640 CB GLN M 100 66.503 4.003 60.922 1.00117.82 C +ATOM 23641 CG GLN M 100 65.195 4.680 61.318 1.00 81.52 C +ATOM 23642 CD GLN M 100 65.374 5.801 62.305 1.00 64.69 C +ATOM 23643 OE1 GLN M 100 66.117 6.780 62.088 1.00 58.40 O +ATOM 23644 NE2 GLN M 100 64.761 5.618 63.464 1.00 71.00 N +ATOM 23645 N GLU M 101 64.965 1.698 58.646 1.00 73.82 N +ATOM 23646 CA GLU M 101 64.298 0.389 58.631 1.00 89.08 C +ATOM 23647 C GLU M 101 65.238 -0.771 58.289 1.00 88.98 C +ATOM 23648 O GLU M 101 64.982 -1.915 58.652 1.00 68.84 O +ATOM 23649 CB GLU M 101 63.104 0.395 57.680 1.00 93.47 C +ATOM 23650 CG GLU M 101 63.419 0.869 56.274 1.00109.74 C +ATOM 23651 CD GLU M 101 62.219 0.750 55.340 1.00109.44 C +ATOM 23652 OE1 GLU M 101 61.086 0.684 55.847 1.00101.22 O +ATOM 23653 OE2 GLU M 101 62.406 0.836 54.104 1.00106.45 O +ATOM 23654 N ASN M 102 66.341 -0.473 57.613 1.00109.68 N +ATOM 23655 CA ASN M 102 67.277 -1.516 57.204 1.00105.25 C +ATOM 23656 C ASN M 102 68.402 -1.762 58.196 1.00 98.22 C +ATOM 23657 O ASN M 102 69.249 -2.624 57.974 1.00100.02 O +ATOM 23658 CB ASN M 102 67.861 -1.175 55.837 1.00104.51 C +ATOM 23659 CG ASN M 102 66.844 -1.331 54.737 1.00100.70 C +ATOM 23660 OD1 ASN M 102 66.531 -2.456 54.300 1.00 75.53 O +ATOM 23661 ND2 ASN M 102 66.271 -0.207 54.317 1.00 99.62 N +ATOM 23662 N GLY M 103 68.447 -0.976 59.262 1.00102.62 N +ATOM 23663 CA GLY M 103 69.514 -1.108 60.251 1.00114.85 C +ATOM 23664 C GLY M 103 70.920 -0.901 59.706 1.00102.97 C +ATOM 23665 O GLY M 103 71.877 -1.549 60.152 1.00117.68 O +ATOM 23666 N THR M 104 71.050 -0.007 58.733 1.00 78.46 N +ATOM 23667 CA THR M 104 72.363 0.431 58.302 1.00 73.76 C +ATOM 23668 C THR M 104 72.655 1.770 58.933 1.00 72.38 C +ATOM 23669 O THR M 104 73.817 2.105 59.136 1.00108.53 O +ATOM 23670 CB THR M 104 72.496 0.511 56.771 1.00 76.12 C +ATOM 23671 OG1 THR M 104 71.593 1.503 56.238 1.00105.54 O +ATOM 23672 CG2 THR M 104 72.182 -0.846 56.156 1.00 89.03 C +ATOM 23673 N VAL M 105 71.621 2.530 59.297 1.00 79.21 N +ATOM 23674 CA VAL M 105 71.830 3.950 59.698 1.00104.68 C +ATOM 23675 C VAL M 105 72.694 4.009 60.953 1.00 91.47 C +ATOM 23676 O VAL M 105 72.568 3.150 61.836 1.00 86.39 O +ATOM 23677 CB VAL M 105 70.496 4.766 59.872 1.00109.53 C +ATOM 23678 CG1 VAL M 105 70.605 5.773 61.017 1.00 96.98 C +ATOM 23679 CG2 VAL M 105 70.100 5.485 58.562 1.00 79.26 C +ATOM 23680 N ALA M 106 73.602 4.988 60.971 1.00 93.36 N +ATOM 23681 CA ALA M 106 74.636 5.095 61.985 1.00117.34 C +ATOM 23682 C ALA M 106 74.014 5.278 63.370 1.00146.98 C +ATOM 23683 O ALA M 106 73.097 6.085 63.546 1.00202.84 O +ATOM 23684 CB ALA M 106 75.561 6.255 61.659 1.00109.67 C +ATOM 23685 N ILE M 107 74.520 4.522 64.343 1.00145.88 N +ATOM 23686 CA ILE M 107 73.938 4.480 65.684 1.00146.42 C +ATOM 23687 C ILE M 107 73.880 5.874 66.357 1.00125.24 C +ATOM 23688 O ILE M 107 72.990 6.153 67.166 1.00 85.02 O +ATOM 23689 CB ILE M 107 74.705 3.464 66.572 1.00142.27 C +ATOM 23690 CG1 ILE M 107 73.935 3.171 67.868 1.00150.20 C +ATOM 23691 CG2 ILE M 107 76.113 3.967 66.882 1.00137.14 C +ATOM 23692 CD1 ILE M 107 72.524 2.640 67.661 1.00132.14 C +ATOM 23693 N ASN M 108 74.840 6.732 66.024 1.00113.70 N +ATOM 23694 CA ASN M 108 74.868 8.112 66.520 1.00129.26 C +ATOM 23695 C ASN M 108 73.760 8.939 65.880 1.00128.30 C +ATOM 23696 O ASN M 108 73.189 9.832 66.504 1.00130.49 O +ATOM 23697 CB ASN M 108 76.217 8.778 66.203 1.00148.08 C +ATOM 23698 CG ASN M 108 77.372 7.793 66.184 1.00155.14 C +ATOM 23699 OD1 ASN M 108 77.966 7.501 67.218 1.00204.49 O +ATOM 23700 ND2 ASN M 108 77.686 7.265 65.006 1.00156.86 N +ATOM 23701 N ASN M 109 73.486 8.641 64.618 1.00123.85 N +ATOM 23702 CA ASN M 109 72.534 9.402 63.821 1.00121.04 C +ATOM 23703 C ASN M 109 71.085 8.927 63.987 1.00108.76 C +ATOM 23704 O ASN M 109 70.149 9.647 63.646 1.00 97.78 O +ATOM 23705 CB ASN M 109 72.932 9.325 62.346 1.00138.78 C +ATOM 23706 CG ASN M 109 73.312 10.676 61.781 1.00166.25 C +ATOM 23707 OD1 ASN M 109 72.623 11.205 60.912 1.00220.75 O +ATOM 23708 ND2 ASN M 109 74.385 11.260 62.302 1.00170.33 N +ATOM 23709 N ARG M 110 70.920 7.723 64.533 1.00103.87 N +ATOM 23710 CA ARG M 110 69.618 7.057 64.640 1.00 79.62 C +ATOM 23711 C ARG M 110 68.620 7.932 65.394 1.00 75.83 C +ATOM 23712 O ARG M 110 68.930 8.469 66.470 1.00 96.19 O +ATOM 23713 CB ARG M 110 69.804 5.717 65.385 1.00 77.42 C +ATOM 23714 CG ARG M 110 68.732 4.684 65.112 1.00 92.20 C +ATOM 23715 CD ARG M 110 69.296 3.263 65.109 1.00113.35 C +ATOM 23716 NE ARG M 110 69.287 2.636 66.430 1.00132.75 N +ATOM 23717 CZ ARG M 110 68.581 1.542 66.756 1.00162.42 C +ATOM 23718 NH1 ARG M 110 67.825 0.894 65.855 1.00119.87 N +ATOM 23719 NH2 ARG M 110 68.634 1.084 68.006 1.00184.36 N +ATOM 23720 N ILE M 111 67.406 8.035 64.880 1.00 65.10 N +ATOM 23721 CA ILE M 111 66.316 8.711 65.620 1.00 77.85 C +ATOM 23722 C ILE M 111 65.279 7.713 66.125 1.00 71.03 C +ATOM 23723 O ILE M 111 64.631 7.066 65.321 1.00 92.17 O +ATOM 23724 CB ILE M 111 65.585 9.751 64.744 1.00 73.34 C +ATOM 23725 CG1 ILE M 111 66.576 10.837 64.344 1.00 95.41 C +ATOM 23726 CG2 ILE M 111 64.399 10.344 65.484 1.00 58.66 C +ATOM 23727 CD1 ILE M 111 66.085 11.756 63.245 1.00102.25 C +ATOM 23728 N PRO M 112 65.118 7.601 67.445 1.00 69.97 N +ATOM 23729 CA PRO M 112 64.181 6.647 67.976 1.00 77.54 C +ATOM 23730 C PRO M 112 62.758 7.197 67.897 1.00 83.97 C +ATOM 23731 O PRO M 112 62.489 8.318 68.353 1.00 91.29 O +ATOM 23732 CB PRO M 112 64.641 6.503 69.424 1.00104.64 C +ATOM 23733 CG PRO M 112 65.206 7.859 69.781 1.00 89.46 C +ATOM 23734 CD PRO M 112 65.716 8.447 68.500 1.00 81.28 C +ATOM 23735 N LEU M 113 61.848 6.378 67.386 1.00103.10 N +ATOM 23736 CA LEU M 113 60.484 6.803 67.146 1.00110.63 C +ATOM 23737 C LEU M 113 59.493 6.164 68.115 1.00 99.31 C +ATOM 23738 O LEU M 113 59.501 4.951 68.374 1.00 76.25 O +ATOM 23739 CB LEU M 113 60.069 6.503 65.700 1.00132.53 C +ATOM 23740 CG LEU M 113 60.440 7.567 64.675 1.00146.27 C +ATOM 23741 CD1 LEU M 113 59.865 7.145 63.336 1.00138.85 C +ATOM 23742 CD2 LEU M 113 59.935 8.954 65.050 1.00155.87 C +ATOM 23743 N GLN M 114 58.531 6.988 68.492 1.00 97.93 N +ATOM 23744 CA GLN M 114 57.584 6.661 69.517 1.00 77.00 C +ATOM 23745 C GLN M 114 56.263 7.260 69.066 1.00 76.27 C +ATOM 23746 O GLN M 114 56.251 8.228 68.316 1.00 76.65 O +ATOM 23747 CB GLN M 114 58.037 7.322 70.801 1.00 72.08 C +ATOM 23748 CG GLN M 114 57.656 6.552 72.021 1.00 83.60 C +ATOM 23749 CD GLN M 114 57.512 7.461 73.190 1.00 98.36 C +ATOM 23750 OE1 GLN M 114 58.173 8.512 73.255 1.00103.22 O +ATOM 23751 NE2 GLN M 114 56.607 7.102 74.121 1.00104.40 N +ATOM 23752 N SER M 115 55.162 6.631 69.454 1.00 79.87 N +ATOM 23753 CA SER M 115 53.821 7.015 68.987 1.00 59.70 C +ATOM 23754 C SER M 115 53.597 8.443 69.360 1.00 68.48 C +ATOM 23755 O SER M 115 54.240 8.968 70.299 1.00100.70 O +ATOM 23756 CB SER M 115 52.741 6.129 69.628 1.00 59.28 C +ATOM 23757 OG SER M 115 52.890 6.046 71.061 1.00 74.14 O +ATOM 23758 N LEU M 116 52.692 9.104 68.656 1.00 97.15 N +ATOM 23759 CA LEU M 116 52.625 10.561 68.797 1.00115.95 C +ATOM 23760 C LEU M 116 51.941 10.863 70.110 1.00 97.13 C +ATOM 23761 O LEU M 116 50.928 10.238 70.395 1.00 89.09 O +ATOM 23762 CB LEU M 116 51.845 11.187 67.652 1.00111.92 C +ATOM 23763 CG LEU M 116 52.475 11.119 66.251 1.00 87.25 C +ATOM 23764 CD1 LEU M 116 51.959 9.912 65.456 1.00 57.36 C +ATOM 23765 CD2 LEU M 116 52.191 12.423 65.537 1.00 70.82 C +ATOM 23766 N THR M 117 52.589 11.661 70.958 1.00 79.03 N +ATOM 23767 CA THR M 117 52.095 11.923 72.306 1.00 81.58 C +ATOM 23768 C THR M 117 50.729 12.481 72.117 1.00 68.66 C +ATOM 23769 O THR M 117 50.560 13.378 71.279 1.00 52.81 O +ATOM 23770 CB THR M 117 52.956 12.971 73.062 1.00 97.31 C +ATOM 23771 OG1 THR M 117 54.312 12.521 73.124 1.00109.52 O +ATOM 23772 CG2 THR M 117 52.450 13.191 74.485 1.00 89.14 C +ATOM 23773 N ALA M 118 49.773 11.980 72.911 1.00 55.73 N +ATOM 23774 CA ALA M 118 48.359 12.302 72.717 1.00 50.84 C +ATOM 23775 C ALA M 118 47.732 13.095 73.817 1.00 47.97 C +ATOM 23776 O ALA M 118 48.016 12.857 74.999 1.00 40.97 O +ATOM 23777 CB ALA M 118 47.579 11.042 72.558 1.00 49.21 C +ATOM 23778 N ALA M 119 46.865 14.027 73.418 1.00 49.38 N +ATOM 23779 CA ALA M 119 46.343 15.033 74.348 1.00 76.87 C +ATOM 23780 C ALA M 119 45.086 14.527 75.026 1.00112.44 C +ATOM 23781 O ALA M 119 44.392 13.671 74.462 1.00110.19 O +ATOM 23782 CB ALA M 119 46.051 16.328 73.612 1.00 69.25 C +ATOM 23783 N ASN M 120 44.780 15.049 76.223 1.00126.61 N +ATOM 23784 CA ASN M 120 43.511 14.711 76.873 1.00143.87 C +ATOM 23785 C ASN M 120 42.422 15.754 76.665 1.00131.91 C +ATOM 23786 O ASN M 120 41.265 15.430 76.385 1.00115.18 O +ATOM 23787 CB ASN M 120 43.664 14.484 78.369 1.00143.06 C +ATOM 23788 CG ASN M 120 42.344 14.034 79.017 1.00152.34 C +ATOM 23789 OD1 ASN M 120 42.022 14.476 80.108 1.00209.50 O +ATOM 23790 ND2 ASN M 120 41.553 13.196 78.317 1.00121.04 N +ATOM 23791 N ILE M 121 42.777 17.010 76.873 1.00128.44 N +ATOM 23792 CA ILE M 121 41.862 18.092 76.554 1.00123.84 C +ATOM 23793 C ILE M 121 42.423 18.817 75.353 1.00112.89 C +ATOM 23794 O ILE M 121 43.625 18.947 75.187 1.00142.02 O +ATOM 23795 CB ILE M 121 41.645 19.070 77.736 1.00108.30 C +ATOM 23796 CG1 ILE M 121 42.864 19.958 77.970 1.00 85.70 C +ATOM 23797 CG2 ILE M 121 41.284 18.297 78.996 1.00135.47 C +ATOM 23798 CD1 ILE M 121 42.630 21.394 77.609 1.00 77.24 C +ATOM 23799 N MET M 122 41.550 19.196 74.452 1.00 95.46 N +ATOM 23800 CA MET M 122 41.968 20.093 73.437 1.00 77.13 C +ATOM 23801 C MET M 122 41.160 21.375 73.593 1.00 74.46 C +ATOM 23802 O MET M 122 39.971 21.350 73.900 1.00 91.44 O +ATOM 23803 CB MET M 122 41.877 19.419 72.062 1.00 61.74 C +ATOM 23804 CG MET M 122 40.518 18.877 71.677 1.00 71.46 C +ATOM 23805 SD MET M 122 40.360 18.798 69.873 1.00110.81 S +ATOM 23806 CE MET M 122 38.679 19.467 69.699 1.00 99.18 C +ATOM 23807 N VAL M 123 41.809 22.505 73.350 1.00 70.51 N +ATOM 23808 CA VAL M 123 41.131 23.804 73.372 1.00 70.59 C +ATOM 23809 C VAL M 123 41.101 24.514 72.013 1.00 68.36 C +ATOM 23810 O VAL M 123 42.110 24.653 71.361 1.00 60.76 O +ATOM 23811 CB VAL M 123 41.805 24.763 74.355 1.00 62.45 C +ATOM 23812 CG1 VAL M 123 43.307 24.652 74.256 1.00 55.66 C +ATOM 23813 CG2 VAL M 123 41.324 26.205 74.143 1.00 59.56 C +ATOM 23814 N GLU M 124 39.906 24.887 71.575 1.00 82.23 N +ATOM 23815 CA GLU M 124 39.753 25.642 70.353 1.00 78.35 C +ATOM 23816 C GLU M 124 38.923 26.859 70.621 1.00 81.28 C +ATOM 23817 O GLU M 124 38.308 27.001 71.668 1.00118.31 O +ATOM 23818 CB GLU M 124 39.107 24.807 69.234 1.00 70.77 C +ATOM 23819 CG GLU M 124 38.154 23.709 69.687 1.00 55.21 C +ATOM 23820 CD GLU M 124 37.939 22.684 68.611 1.00 58.94 C +ATOM 23821 OE1 GLU M 124 38.887 22.400 67.831 1.00 61.41 O +ATOM 23822 OE2 GLU M 124 36.797 22.226 68.462 1.00 64.35 O +ATOM 23823 N GLY M 125 38.905 27.743 69.641 1.00 94.26 N +ATOM 23824 CA GLY M 125 38.231 29.014 69.787 1.00 83.47 C +ATOM 23825 C GLY M 125 38.255 29.801 68.475 1.00 66.61 C +ATOM 23826 O GLY M 125 38.378 29.228 67.400 1.00 45.55 O +ATOM 23827 N SER M 126 38.006 31.099 68.569 1.00 47.30 N +ATOM 23828 CA SER M 126 37.734 31.898 67.389 1.00 44.68 C +ATOM 23829 C SER M 126 37.871 33.325 67.739 1.00 48.74 C +ATOM 23830 O SER M 126 37.591 33.733 68.881 1.00 93.78 O +ATOM 23831 CB SER M 126 36.300 31.690 66.859 1.00 52.02 C +ATOM 23832 OG SER M 126 35.779 30.369 67.093 1.00 69.11 O +ATOM 23833 N ILE M 127 38.361 34.108 66.812 1.00 59.64 N +ATOM 23834 CA ILE M 127 38.288 35.558 66.983 1.00 83.62 C +ATOM 23835 C ILE M 127 36.878 35.982 66.631 1.00 93.88 C +ATOM 23836 O ILE M 127 36.501 35.985 65.459 1.00119.35 O +ATOM 23837 CB ILE M 127 39.306 36.319 66.110 1.00 98.17 C +ATOM 23838 CG1 ILE M 127 40.743 36.011 66.577 1.00106.00 C +ATOM 23839 CG2 ILE M 127 39.027 37.822 66.141 1.00 62.52 C +ATOM 23840 CD1 ILE M 127 41.776 36.050 65.465 1.00116.60 C +ATOM 23841 N ILE M 128 36.085 36.256 67.661 1.00 86.03 N +ATOM 23842 CA ILE M 128 34.666 36.599 67.510 1.00 80.92 C +ATOM 23843 C ILE M 128 34.630 38.110 67.515 1.00 86.27 C +ATOM 23844 O ILE M 128 34.881 38.773 68.513 1.00116.86 O +ATOM 23845 CB ILE M 128 33.812 35.997 68.642 1.00 85.64 C +ATOM 23846 CG1 ILE M 128 34.402 36.336 70.008 1.00122.39 C +ATOM 23847 CG2 ILE M 128 33.832 34.478 68.568 1.00103.00 C +ATOM 23848 CD1 ILE M 128 33.368 36.312 71.118 1.00165.51 C +ATOM 23849 N GLY M 129 34.578 38.667 66.323 1.00100.67 N +ATOM 23850 CA GLY M 129 34.311 40.100 66.196 1.00 80.59 C +ATOM 23851 C GLY M 129 35.445 41.106 66.325 1.00 79.58 C +ATOM 23852 O GLY M 129 36.400 40.957 67.121 1.00 81.52 O +ATOM 23853 N TYR M 130 35.436 42.025 65.374 1.00 85.75 N +ATOM 23854 CA TYR M 130 36.254 43.215 65.444 1.00 84.74 C +ATOM 23855 C TYR M 130 35.354 44.313 64.925 1.00100.73 C +ATOM 23856 O TYR M 130 35.034 44.354 63.751 1.00100.26 O +ATOM 23857 CB TYR M 130 37.524 43.101 64.581 1.00 72.86 C +ATOM 23858 CG TYR M 130 38.363 44.358 64.516 1.00 56.88 C +ATOM 23859 CD1 TYR M 130 37.948 45.447 63.770 1.00 64.28 C +ATOM 23860 CD2 TYR M 130 39.616 44.415 65.115 1.00 65.91 C +ATOM 23861 CE1 TYR M 130 38.736 46.576 63.651 1.00 86.63 C +ATOM 23862 CE2 TYR M 130 40.435 45.521 64.967 1.00 90.90 C +ATOM 23863 CZ TYR M 130 39.982 46.608 64.257 1.00100.37 C +ATOM 23864 OH TYR M 130 40.780 47.723 64.161 1.00115.10 O +ATOM 23865 N GLU M 131 34.858 45.129 65.832 1.00112.58 N +ATOM 23866 CA GLU M 131 34.124 46.324 65.440 1.00129.29 C +ATOM 23867 C GLU M 131 35.083 47.503 65.455 1.00101.29 C +ATOM 23868 O GLU M 131 36.034 47.520 66.243 1.00 90.96 O +ATOM 23869 CB GLU M 131 32.951 46.537 66.399 1.00171.48 C +ATOM 23870 CG GLU M 131 31.958 47.622 66.003 1.00128.74 C +ATOM 23871 CD GLU M 131 30.830 47.132 65.112 1.00134.94 C +ATOM 23872 OE1 GLU M 131 30.495 45.917 65.151 1.00172.01 O +ATOM 23873 OE2 GLU M 131 30.334 47.946 64.307 1.00119.75 O +ATOM 23874 N SER M 132 34.880 48.437 64.539 1.00 87.63 N +ATOM 23875 CA SER M 132 35.847 49.501 64.331 1.00 93.98 C +ATOM 23876 C SER M 132 35.242 50.878 64.607 1.00113.34 C +ATOM 23877 O SER M 132 34.086 51.143 64.273 1.00108.30 O +ATOM 23878 CB SER M 132 36.400 49.442 62.912 1.00 87.34 C +ATOM 23879 OG SER M 132 35.976 50.555 62.152 1.00 84.54 O +ATOM 23880 N ASN M 133 36.045 51.759 65.198 1.00136.84 N +ATOM 23881 CA ASN M 133 35.552 53.042 65.724 1.00147.86 C +ATOM 23882 C ASN M 133 34.285 52.861 66.555 1.00138.27 C +ATOM 23883 O ASN M 133 33.252 53.465 66.275 1.00114.02 O +ATOM 23884 CB ASN M 133 35.302 54.043 64.599 1.00130.09 C +ATOM 23885 CG ASN M 133 36.556 54.347 63.802 1.00141.85 C +ATOM 23886 OD1 ASN M 133 37.681 54.269 64.310 1.00145.75 O +ATOM 23887 ND2 ASN M 133 36.366 54.649 62.535 1.00155.12 N +ATOM 23888 N VAL M 134 34.396 52.012 67.572 1.00133.08 N +ATOM 23889 CA VAL M 134 33.301 51.734 68.476 1.00122.61 C +ATOM 23890 C VAL M 134 33.040 53.015 69.257 1.00119.54 C +ATOM 23891 O VAL M 134 31.889 53.351 69.568 1.00106.00 O +ATOM 23892 CB VAL M 134 33.642 50.551 69.420 1.00131.07 C +ATOM 23893 CG1 VAL M 134 32.463 50.213 70.318 1.00148.05 C +ATOM 23894 CG2 VAL M 134 34.042 49.323 68.609 1.00122.02 C +ATOM 23895 N LYS M 135 34.116 53.742 69.560 1.00127.24 N +ATOM 23896 CA LYS M 135 33.999 55.135 69.999 1.00125.38 C +ATOM 23897 C LYS M 135 35.016 56.022 69.306 1.00127.19 C +ATOM 23898 O LYS M 135 36.061 55.551 68.831 1.00131.21 O +ATOM 23899 CB LYS M 135 34.187 55.243 71.514 1.00123.00 C +ATOM 23900 CG LYS M 135 33.126 54.500 72.313 1.00126.06 C +ATOM 23901 CD LYS M 135 33.438 54.556 73.795 1.00113.16 C +ATOM 23902 CE LYS M 135 32.401 53.810 74.605 1.00110.44 C +ATOM 23903 NZ LYS M 135 32.424 54.278 76.013 1.00118.98 N +ATOM 23904 N SER M 136 34.718 57.317 69.281 1.00138.36 N +ATOM 23905 CA SER M 136 35.624 58.293 68.681 1.00153.42 C +ATOM 23906 C SER M 136 35.297 59.719 69.108 1.00138.97 C +ATOM 23907 O SER M 136 34.188 60.000 69.556 1.00103.89 O +ATOM 23908 CB SER M 136 35.583 58.199 67.162 1.00148.50 C +ATOM 23909 OG SER M 136 35.278 59.453 66.579 1.00113.25 O +ATOM 23910 N GLY M 137 36.301 60.593 69.040 1.00136.33 N +ATOM 23911 CA GLY M 137 36.120 61.988 69.429 1.00144.29 C +ATOM 23912 C GLY M 137 37.266 62.891 69.009 1.00141.44 C +ATOM 23913 O GLY M 137 38.273 62.429 68.478 1.00 93.35 O +ATOM 23914 N GLY M 138 37.091 64.192 69.223 1.00142.57 N +ATOM 23915 CA GLY M 138 38.108 65.172 68.867 1.00134.83 C +ATOM 23916 C GLY M 138 37.879 66.519 69.508 1.00105.85 C +ATOM 23917 O GLY M 138 36.741 66.931 69.706 1.00 95.88 O +ATOM 23918 N VAL M 139 38.970 67.179 69.877 1.00108.84 N +ATOM 23919 CA VAL M 139 38.904 68.498 70.490 1.00105.15 C +ATOM 23920 C VAL M 139 40.023 69.365 69.943 1.00112.61 C +ATOM 23921 O VAL M 139 41.203 69.000 70.014 1.00104.13 O +ATOM 23922 CB VAL M 139 39.035 68.449 72.032 1.00102.86 C +ATOM 23923 CG1 VAL M 139 39.094 69.860 72.597 1.00 97.56 C +ATOM 23924 CG2 VAL M 139 37.884 67.666 72.661 1.00 98.25 C +ATOM 23925 N GLY M 140 39.657 70.538 69.440 1.00131.21 N +ATOM 23926 CA GLY M 140 40.633 71.460 68.866 1.00134.45 C +ATOM 23927 C GLY M 140 40.256 72.915 69.015 1.00116.56 C +ATOM 23928 O GLY M 140 39.075 73.269 68.961 1.00132.43 O +ATOM 23929 N ALA M 141 41.267 73.769 69.128 1.00101.31 N +ATOM 23930 CA ALA M 141 41.036 75.206 69.123 1.00107.78 C +ATOM 23931 C ALA M 141 42.137 75.958 68.383 1.00118.06 C +ATOM 23932 O ALA M 141 43.322 75.623 68.471 1.00129.64 O +ATOM 23933 CB ALA M 141 40.893 75.717 70.547 1.00109.33 C +ATOM 23934 N ARG M 142 41.734 76.976 67.642 1.00136.56 N +ATOM 23935 CA ARG M 142 42.688 77.891 67.056 1.00175.77 C +ATOM 23936 C ARG M 142 42.286 79.313 67.414 1.00187.45 C +ATOM 23937 O ARG M 142 41.098 79.627 67.508 1.00221.53 O +ATOM 23938 CB ARG M 142 42.775 77.707 65.536 1.00184.55 C +ATOM 23939 CG ARG M 142 43.836 78.593 64.891 1.00182.73 C +ATOM 23940 CD ARG M 142 44.619 77.864 63.826 1.00165.86 C +ATOM 23941 NE ARG M 142 43.808 77.784 62.619 1.00157.98 N +ATOM 23942 CZ ARG M 142 43.914 76.822 61.709 1.00185.04 C +ATOM 23943 NH1 ARG M 142 44.868 75.897 61.795 1.00195.41 N +ATOM 23944 NH2 ARG M 142 43.106 76.826 60.657 1.00210.16 N +ATOM 23945 N TYR M 143 43.288 80.161 67.625 1.00176.52 N +ATOM 23946 CA TYR M 143 43.075 81.518 68.105 1.00168.16 C +ATOM 23947 C TYR M 143 43.870 82.501 67.239 1.00147.76 C +ATOM 23948 O TYR M 143 44.955 82.964 67.611 1.00136.53 O +ATOM 23949 CB TYR M 143 43.495 81.610 69.571 1.00182.24 C +ATOM 23950 CG TYR M 143 43.172 82.918 70.229 1.00201.44 C +ATOM 23951 CD1 TYR M 143 41.862 83.250 70.542 1.00201.20 C +ATOM 23952 CD2 TYR M 143 44.178 83.808 70.570 1.00205.49 C +ATOM 23953 CE1 TYR M 143 41.558 84.438 71.178 1.00193.80 C +ATOM 23954 CE2 TYR M 143 43.887 84.998 71.215 1.00205.43 C +ATOM 23955 CZ TYR M 143 42.574 85.309 71.511 1.00191.56 C +ATOM 23956 OH TYR M 143 42.277 86.496 72.133 1.00184.99 O +ATOM 23957 N GLY M 145 45.792 82.837 65.382 1.00167.06 N +ATOM 23958 CA GLY M 145 47.013 82.401 64.712 1.00172.51 C +ATOM 23959 C GLY M 145 47.588 81.080 65.204 1.00195.71 C +ATOM 23960 O GLY M 145 48.283 80.399 64.449 1.00176.58 O +ATOM 23961 N ILE M 146 47.296 80.711 66.457 1.00224.33 N +ATOM 23962 CA ILE M 146 47.922 79.544 67.115 1.00179.48 C +ATOM 23963 C ILE M 146 46.846 78.490 67.393 1.00142.85 C +ATOM 23964 O ILE M 146 45.744 78.828 67.811 1.00127.00 O +ATOM 23965 CB ILE M 146 48.617 79.927 68.455 1.00144.70 C +ATOM 23966 CG1 ILE M 146 49.333 81.284 68.329 1.00146.10 C +ATOM 23967 CG2 ILE M 146 49.603 78.851 68.877 1.00104.87 C +ATOM 23968 CD1 ILE M 146 48.524 82.467 68.836 1.00131.53 C +ATOM 23969 N GLY M 147 47.149 77.223 67.131 1.00119.61 N +ATOM 23970 CA GLY M 147 46.137 76.176 67.281 1.00125.46 C +ATOM 23971 C GLY M 147 46.648 74.792 67.634 1.00124.45 C +ATOM 23972 O GLY M 147 47.796 74.450 67.356 1.00112.91 O +ATOM 23973 N ALA M 148 45.775 73.997 68.241 1.00128.98 N +ATOM 23974 CA ALA M 148 46.067 72.601 68.494 1.00120.74 C +ATOM 23975 C ALA M 148 44.784 71.779 68.454 1.00114.48 C +ATOM 23976 O ALA M 148 43.673 72.318 68.466 1.00 82.96 O +ATOM 23977 CB ALA M 148 46.773 72.436 69.835 1.00109.45 C +ATOM 23978 N ASP M 149 44.951 70.466 68.387 1.00129.72 N +ATOM 23979 CA ASP M 149 43.806 69.560 68.381 1.00152.58 C +ATOM 23980 C ASP M 149 44.246 68.122 68.632 1.00152.16 C +ATOM 23981 O ASP M 149 45.358 67.735 68.261 1.00153.38 O +ATOM 23982 CB ASP M 149 43.036 69.661 67.054 1.00166.13 C +ATOM 23983 CG ASP M 149 43.675 68.873 65.954 1.00168.88 C +ATOM 23984 OD1 ASP M 149 44.710 69.336 65.423 1.00177.67 O +ATOM 23985 OD2 ASP M 149 43.145 67.801 65.601 1.00152.69 O +ATOM 23986 N THR M 150 43.387 67.347 69.282 1.00139.61 N +ATOM 23987 CA THR M 150 43.564 65.905 69.319 1.00128.74 C +ATOM 23988 C THR M 150 42.321 65.221 68.802 1.00107.22 C +ATOM 23989 O THR M 150 41.229 65.794 68.765 1.00112.60 O +ATOM 23990 CB THR M 150 43.846 65.370 70.731 1.00142.76 C +ATOM 23991 OG1 THR M 150 42.757 65.712 71.597 1.00176.61 O +ATOM 23992 CG2 THR M 150 45.141 65.935 71.279 1.00137.66 C +ATOM 23993 N GLN M 151 42.515 63.998 68.346 1.00112.32 N +ATOM 23994 CA GLN M 151 41.433 63.166 67.871 1.00115.02 C +ATOM 23995 C GLN M 151 41.707 61.754 68.282 1.00118.45 C +ATOM 23996 O GLN M 151 42.858 61.345 68.290 1.00133.70 O +ATOM 23997 CB GLN M 151 41.415 63.266 66.362 1.00128.22 C +ATOM 23998 CG GLN M 151 40.293 62.614 65.592 1.00138.34 C +ATOM 23999 CD GLN M 151 40.334 63.081 64.153 1.00148.24 C +ATOM 24000 OE1 GLN M 151 41.416 63.339 63.622 1.00111.95 O +ATOM 24001 NE2 GLN M 151 39.167 63.331 63.567 1.00176.53 N +ATOM 24002 N TYR M 152 40.672 61.015 68.648 1.00102.32 N +ATOM 24003 CA TYR M 152 40.870 59.641 69.075 1.00 96.18 C +ATOM 24004 C TYR M 152 39.796 58.722 68.558 1.00109.32 C +ATOM 24005 O TYR M 152 38.654 59.129 68.359 1.00 99.03 O +ATOM 24006 CB TYR M 152 40.943 59.554 70.595 1.00 87.32 C +ATOM 24007 CG TYR M 152 39.727 58.991 71.300 1.00 78.47 C +ATOM 24008 CD1 TYR M 152 38.506 59.643 71.265 1.00 74.66 C +ATOM 24009 CD2 TYR M 152 39.845 57.879 72.110 1.00 89.46 C +ATOM 24010 CE1 TYR M 152 37.412 59.160 71.970 1.00 87.62 C +ATOM 24011 CE2 TYR M 152 38.771 57.404 72.843 1.00102.08 C +ATOM 24012 CZ TYR M 152 37.552 58.038 72.759 1.00 99.37 C +ATOM 24013 OH TYR M 152 36.482 57.560 73.488 1.00126.87 O +ATOM 24014 N GLN M 153 40.188 57.485 68.294 1.00128.16 N +ATOM 24015 CA GLN M 153 39.228 56.455 67.961 1.00137.57 C +ATOM 24016 C GLN M 153 39.582 55.194 68.722 1.00115.29 C +ATOM 24017 O GLN M 153 40.751 54.957 69.045 1.00125.54 O +ATOM 24018 CB GLN M 153 39.222 56.207 66.442 1.00191.55 C +ATOM 24019 CG GLN M 153 38.719 57.386 65.591 1.00222.09 C +ATOM 24020 CD GLN M 153 38.842 57.097 64.080 1.00261.18 C +ATOM 24021 OE1 GLN M 153 39.630 56.241 63.655 1.00265.44 O +ATOM 24022 NE2 GLN M 153 38.078 57.825 63.268 1.00283.50 N +ATOM 24023 N LEU M 154 38.589 54.352 68.965 1.00 91.79 N +ATOM 24024 CA LEU M 154 38.870 53.031 69.518 1.00 93.39 C +ATOM 24025 C LEU M 154 37.965 51.925 68.994 1.00 91.52 C +ATOM 24026 O LEU M 154 36.764 52.145 68.723 1.00 74.40 O +ATOM 24027 CB LEU M 154 38.806 53.066 71.038 1.00 83.95 C +ATOM 24028 CG LEU M 154 37.405 53.211 71.632 1.00101.14 C +ATOM 24029 CD1 LEU M 154 36.809 51.867 72.000 1.00 84.75 C +ATOM 24030 CD2 LEU M 154 37.475 54.133 72.840 1.00147.67 C +ATOM 24031 N ASP M 155 38.561 50.730 68.906 1.00 91.78 N +ATOM 24032 CA ASP M 155 37.983 49.574 68.224 1.00 94.88 C +ATOM 24033 C ASP M 155 37.866 48.440 69.225 1.00 92.58 C +ATOM 24034 O ASP M 155 38.538 48.453 70.257 1.00 77.07 O +ATOM 24035 CB ASP M 155 38.881 49.142 67.054 1.00 95.65 C +ATOM 24036 CG ASP M 155 39.304 50.313 66.180 1.00126.11 C +ATOM 24037 OD1 ASP M 155 40.238 51.047 66.574 1.00139.80 O +ATOM 24038 OD2 ASP M 155 38.700 50.510 65.102 1.00121.83 O +ATOM 24039 N GLN M 156 37.021 47.453 68.928 1.00 86.65 N +ATOM 24040 CA GLN M 156 36.878 46.291 69.811 1.00 85.21 C +ATOM 24041 C GLN M 156 37.394 44.997 69.169 1.00 81.87 C +ATOM 24042 O GLN M 156 37.401 44.868 67.950 1.00115.19 O +ATOM 24043 CB GLN M 156 35.417 46.160 70.238 1.00 84.06 C +ATOM 24044 CG GLN M 156 35.187 45.191 71.389 1.00 87.94 C +ATOM 24045 CD GLN M 156 33.879 45.454 72.121 1.00 93.96 C +ATOM 24046 OE1 GLN M 156 33.025 46.237 71.658 1.00 94.14 O +ATOM 24047 NE2 GLN M 156 33.701 44.779 73.254 1.00 72.27 N +ATOM 24048 N ILE M 157 37.784 44.034 69.995 1.00 67.46 N +ATOM 24049 CA ILE M 157 38.148 42.692 69.518 1.00 62.49 C +ATOM 24050 C ILE M 157 37.825 41.645 70.598 1.00 51.69 C +ATOM 24051 O ILE M 157 37.910 41.937 71.792 1.00 58.18 O +ATOM 24052 CB ILE M 157 39.639 42.654 69.187 1.00 59.38 C +ATOM 24053 CG1 ILE M 157 39.936 41.558 68.189 1.00 65.48 C +ATOM 24054 CG2 ILE M 157 40.454 42.440 70.447 1.00 58.50 C +ATOM 24055 CD1 ILE M 157 41.364 41.564 67.659 1.00 60.87 C +ATOM 24056 N ALA M 158 37.255 40.528 70.195 1.00 48.38 N +ATOM 24057 CA ALA M 158 36.802 39.569 71.175 1.00 64.49 C +ATOM 24058 C ALA M 158 37.245 38.199 70.754 1.00 87.15 C +ATOM 24059 O ALA M 158 37.422 37.910 69.567 1.00 62.78 O +ATOM 24060 CB ALA M 158 35.288 39.600 71.373 1.00 62.37 C +ATOM 24061 N VAL M 159 37.458 37.353 71.754 1.00 97.19 N +ATOM 24062 CA VAL M 159 38.012 36.035 71.523 1.00 99.20 C +ATOM 24063 C VAL M 159 37.256 35.013 72.364 1.00 83.71 C +ATOM 24064 O VAL M 159 37.127 35.161 73.569 1.00112.16 O +ATOM 24065 CB VAL M 159 39.535 36.011 71.823 1.00100.75 C +ATOM 24066 CG1 VAL M 159 40.033 34.598 72.056 1.00 94.11 C +ATOM 24067 CG2 VAL M 159 40.315 36.645 70.680 1.00 97.25 C +ATOM 24068 N ASN M 160 36.791 33.961 71.707 1.00 69.16 N +ATOM 24069 CA ASN M 160 36.324 32.763 72.374 1.00 73.81 C +ATOM 24070 C ASN M 160 37.476 31.732 72.471 1.00 83.27 C +ATOM 24071 O ASN M 160 38.175 31.459 71.496 1.00 72.11 O +ATOM 24072 CB ASN M 160 35.161 32.187 71.568 1.00 72.64 C +ATOM 24073 CG ASN M 160 34.611 30.875 72.118 1.00 89.51 C +ATOM 24074 OD1 ASN M 160 35.351 29.947 72.473 1.00 75.21 O +ATOM 24075 ND2 ASN M 160 33.287 30.785 72.155 1.00 92.83 N +ATOM 24076 N LEU M 161 37.696 31.207 73.671 1.00 88.23 N +ATOM 24077 CA LEU M 161 38.470 29.973 73.853 1.00 77.87 C +ATOM 24078 C LEU M 161 37.634 28.969 74.620 1.00 79.50 C +ATOM 24079 O LEU M 161 36.785 29.341 75.437 1.00143.19 O +ATOM 24080 CB LEU M 161 39.740 30.243 74.636 1.00 73.12 C +ATOM 24081 CG LEU M 161 40.747 31.143 73.957 1.00 94.12 C +ATOM 24082 CD1 LEU M 161 41.873 31.476 74.924 1.00 88.51 C +ATOM 24083 CD2 LEU M 161 41.271 30.471 72.699 1.00110.76 C +ATOM 24084 N ARG M 162 37.819 27.698 74.342 1.00 69.70 N +ATOM 24085 CA ARG M 162 36.987 26.693 75.001 1.00 60.45 C +ATOM 24086 C ARG M 162 37.617 25.336 75.072 1.00 55.94 C +ATOM 24087 O ARG M 162 38.187 24.825 74.089 1.00115.22 O +ATOM 24088 CB ARG M 162 35.594 26.597 74.358 1.00 63.87 C +ATOM 24089 CG ARG M 162 35.511 26.149 72.903 1.00 78.56 C +ATOM 24090 CD ARG M 162 34.080 25.696 72.568 1.00 84.63 C +ATOM 24091 NE ARG M 162 33.898 25.046 71.265 1.00 84.25 N +ATOM 24092 CZ ARG M 162 33.823 25.711 70.114 1.00 98.80 C +ATOM 24093 NH1 ARG M 162 33.982 27.041 70.068 1.00100.67 N +ATOM 24094 NH2 ARG M 162 33.655 25.038 68.988 1.00102.93 N +ATOM 24095 N VAL M 163 37.621 24.799 76.267 1.00 54.26 N +ATOM 24096 CA VAL M 163 38.198 23.487 76.534 1.00 71.34 C +ATOM 24097 C VAL M 163 37.184 22.421 76.198 1.00 57.12 C +ATOM 24098 O VAL M 163 36.120 22.368 76.829 1.00 99.24 O +ATOM 24099 CB VAL M 163 38.572 23.313 78.037 1.00 86.25 C +ATOM 24100 CG1 VAL M 163 39.131 21.897 78.289 1.00 82.30 C +ATOM 24101 CG2 VAL M 163 39.533 24.422 78.494 1.00 75.65 C +ATOM 24102 N VAL M 164 37.604 21.476 75.377 1.00 40.22 N +ATOM 24103 CA VAL M 164 36.781 20.341 75.004 1.00 42.14 C +ATOM 24104 C VAL M 164 37.413 19.090 75.509 1.00 43.02 C +ATOM 24105 O VAL M 164 38.607 18.896 75.358 1.00 51.17 O +ATOM 24106 CB VAL M 164 36.661 20.206 73.481 1.00 48.35 C +ATOM 24107 CG1 VAL M 164 35.822 19.010 73.097 1.00 36.29 C +ATOM 24108 CG2 VAL M 164 36.044 21.481 72.912 1.00 74.50 C +ATOM 24109 N ASN M 165 36.594 18.240 76.106 1.00 60.24 N +ATOM 24110 CA ASN M 165 37.058 16.967 76.599 1.00 72.88 C +ATOM 24111 C ASN M 165 37.077 15.921 75.469 1.00101.80 C +ATOM 24112 O ASN M 165 36.033 15.574 74.903 1.00 78.72 O +ATOM 24113 CB ASN M 165 36.186 16.460 77.731 1.00 69.19 C +ATOM 24114 CG ASN M 165 36.814 15.281 78.442 1.00 94.73 C +ATOM 24115 OD1 ASN M 165 37.947 14.894 78.155 1.00 94.21 O +ATOM 24116 ND2 ASN M 165 36.017 14.594 79.232 1.00135.23 N +ATOM 24117 N VAL M 166 38.278 15.411 75.165 1.00104.27 N +ATOM 24118 CA VAL M 166 38.486 14.445 74.077 1.00 74.42 C +ATOM 24119 C VAL M 166 37.662 13.210 74.315 1.00 67.40 C +ATOM 24120 O VAL M 166 37.092 12.664 73.403 1.00 58.62 O +ATOM 24121 CB VAL M 166 39.985 14.062 73.952 1.00 70.37 C +ATOM 24122 CG1 VAL M 166 40.172 12.690 73.306 1.00 58.70 C +ATOM 24123 CG2 VAL M 166 40.731 15.172 73.203 1.00 82.66 C +ATOM 24124 N SER M 167 37.594 12.801 75.574 1.00 74.51 N +ATOM 24125 CA SER M 167 37.004 11.536 75.927 1.00 83.23 C +ATOM 24126 C SER M 167 35.481 11.536 75.760 1.00 88.22 C +ATOM 24127 O SER M 167 34.866 10.461 75.809 1.00 78.50 O +ATOM 24128 CB SER M 167 37.409 11.168 77.359 1.00 96.67 C +ATOM 24129 OG SER M 167 38.802 11.379 77.569 1.00119.85 O +ATOM 24130 N THR M 168 34.873 12.721 75.605 1.00 79.71 N +ATOM 24131 CA THR M 168 33.411 12.811 75.559 1.00 74.58 C +ATOM 24132 C THR M 168 32.904 13.768 74.532 1.00 59.91 C +ATOM 24133 O THR M 168 31.817 13.577 73.929 1.00 74.97 O +ATOM 24134 CB THR M 168 32.810 13.247 76.912 1.00 83.90 C +ATOM 24135 OG1 THR M 168 33.471 14.423 77.379 1.00 74.96 O +ATOM 24136 CG2 THR M 168 32.949 12.130 77.957 1.00101.67 C +ATOM 24137 N GLY M 169 33.622 14.855 74.364 1.00 50.25 N +ATOM 24138 CA GLY M 169 33.101 15.892 73.485 1.00 77.51 C +ATOM 24139 C GLY M 169 32.340 16.961 74.239 1.00 65.34 C +ATOM 24140 O GLY M 169 32.049 18.013 73.688 1.00 56.70 O +ATOM 24141 N GLU M 170 32.057 16.699 75.506 1.00 69.65 N +ATOM 24142 CA GLU M 170 31.594 17.748 76.407 1.00 68.38 C +ATOM 24143 C GLU M 170 32.565 18.894 76.351 1.00 54.01 C +ATOM 24144 O GLU M 170 33.788 18.716 76.486 1.00 65.80 O +ATOM 24145 CB GLU M 170 31.520 17.242 77.866 1.00101.19 C +ATOM 24146 CG GLU M 170 30.312 16.357 78.161 1.00125.12 C +ATOM 24147 CD GLU M 170 30.579 15.226 79.153 1.00137.49 C +ATOM 24148 OE1 GLU M 170 31.757 14.955 79.458 1.00125.34 O +ATOM 24149 OE2 GLU M 170 29.613 14.531 79.544 1.00148.16 O +ATOM 24150 N ILE M 171 32.051 20.080 76.132 1.00 45.55 N +ATOM 24151 CA ILE M 171 32.864 21.262 76.346 1.00 59.91 C +ATOM 24152 C ILE M 171 32.992 21.493 77.840 1.00 80.63 C +ATOM 24153 O ILE M 171 31.992 21.469 78.561 1.00142.08 O +ATOM 24154 CB ILE M 171 32.213 22.488 75.712 1.00 75.53 C +ATOM 24155 CG1 ILE M 171 32.332 22.391 74.181 1.00105.17 C +ATOM 24156 CG2 ILE M 171 32.870 23.754 76.238 1.00 74.63 C +ATOM 24157 CD1 ILE M 171 31.408 23.325 73.440 1.00 97.90 C +ATOM 24158 N LEU M 172 34.220 21.603 78.336 1.00 82.75 N +ATOM 24159 CA LEU M 172 34.438 21.664 79.786 1.00 70.46 C +ATOM 24160 C LEU M 172 34.472 23.100 80.266 1.00 63.41 C +ATOM 24161 O LEU M 172 34.466 23.371 81.476 1.00114.53 O +ATOM 24162 CB LEU M 172 35.711 20.889 80.210 1.00 62.48 C +ATOM 24163 CG LEU M 172 35.598 19.336 80.113 1.00 72.49 C +ATOM 24164 CD1 LEU M 172 36.768 18.498 80.637 1.00 64.76 C +ATOM 24165 CD2 LEU M 172 34.272 18.796 80.647 1.00 80.93 C +ATOM 24166 N SER M 173 34.584 24.014 79.322 1.00 55.74 N +ATOM 24167 CA SER M 173 34.705 25.408 79.642 1.00 73.25 C +ATOM 24168 C SER M 173 34.652 26.252 78.382 1.00 94.44 C +ATOM 24169 O SER M 173 35.410 26.036 77.433 1.00130.42 O +ATOM 24170 CB SER M 173 36.032 25.705 80.373 1.00100.41 C +ATOM 24171 OG SER M 173 36.285 27.104 80.399 1.00168.01 O +ATOM 24172 N SER M 174 33.828 27.292 78.406 1.00115.28 N +ATOM 24173 CA SER M 174 33.857 28.327 77.358 1.00110.42 C +ATOM 24174 C SER M 174 34.059 29.677 77.996 1.00 80.24 C +ATOM 24175 O SER M 174 33.473 29.973 79.036 1.00 80.36 O +ATOM 24176 CB SER M 174 32.546 28.344 76.547 1.00130.29 C +ATOM 24177 OG SER M 174 32.641 29.159 75.385 1.00115.42 O +ATOM 24178 N VAL M 175 34.909 30.485 77.384 1.00 77.08 N +ATOM 24179 CA VAL M 175 35.197 31.825 77.896 1.00103.84 C +ATOM 24180 C VAL M 175 35.226 32.839 76.766 1.00 91.42 C +ATOM 24181 O VAL M 175 35.739 32.543 75.678 1.00133.24 O +ATOM 24182 CB VAL M 175 36.536 31.880 78.690 1.00117.67 C +ATOM 24183 CG1 VAL M 175 36.463 30.994 79.924 1.00131.91 C +ATOM 24184 CG2 VAL M 175 37.714 31.444 77.840 1.00135.96 C +ATOM 24185 N ASN M 176 34.792 34.053 77.074 1.00 75.39 N +ATOM 24186 CA ASN M 176 34.646 35.088 76.076 1.00 84.28 C +ATOM 24187 C ASN M 176 35.355 36.367 76.495 1.00 89.52 C +ATOM 24188 O ASN M 176 34.749 37.214 77.144 1.00129.40 O +ATOM 24189 CB ASN M 176 33.153 35.353 75.882 1.00 79.99 C +ATOM 24190 CG ASN M 176 32.559 34.599 74.704 1.00 97.12 C +ATOM 24191 OD1 ASN M 176 31.417 34.890 74.216 1.00146.16 O +ATOM 24192 ND2 ASN M 176 33.334 33.659 74.181 1.00 95.59 N +ATOM 24193 N THR M 177 36.600 36.565 76.054 1.00 88.07 N +ATOM 24194 CA THR M 177 37.356 37.771 76.410 1.00 88.41 C +ATOM 24195 C THR M 177 37.275 38.869 75.340 1.00 83.58 C +ATOM 24196 O THR M 177 36.929 38.607 74.194 1.00 70.64 O +ATOM 24197 CB THR M 177 38.837 37.455 76.672 1.00 91.41 C +ATOM 24198 OG1 THR M 177 39.479 37.132 75.436 1.00113.19 O +ATOM 24199 CG2 THR M 177 38.980 36.286 77.642 1.00 80.46 C +ATOM 24200 N SER M 178 37.564 40.101 75.747 1.00 83.43 N +ATOM 24201 CA SER M 178 37.426 41.257 74.871 1.00 93.17 C +ATOM 24202 C SER M 178 38.483 42.294 75.184 1.00 83.58 C +ATOM 24203 O SER M 178 38.948 42.414 76.322 1.00107.06 O +ATOM 24204 CB SER M 178 36.033 41.892 75.002 1.00117.72 C +ATOM 24205 OG SER M 178 35.984 43.191 74.404 1.00129.92 O +ATOM 24206 N LYS M 179 38.814 43.103 74.188 1.00 78.46 N +ATOM 24207 CA LYS M 179 39.876 44.070 74.351 1.00 89.54 C +ATOM 24208 C LYS M 179 39.695 45.243 73.391 1.00118.20 C +ATOM 24209 O LYS M 179 39.222 45.087 72.265 1.00149.27 O +ATOM 24210 CB LYS M 179 41.209 43.369 74.117 1.00 88.81 C +ATOM 24211 CG LYS M 179 42.339 43.855 75.004 1.00113.94 C +ATOM 24212 CD LYS M 179 43.140 44.923 74.294 1.00122.36 C +ATOM 24213 CE LYS M 179 44.158 45.535 75.232 1.00128.50 C +ATOM 24214 NZ LYS M 179 44.739 46.776 74.660 1.00122.36 N +ATOM 24215 N THR M 180 40.072 46.429 73.854 1.00133.24 N +ATOM 24216 CA THR M 180 39.877 47.653 73.083 1.00119.93 C +ATOM 24217 C THR M 180 41.202 48.173 72.503 1.00127.17 C +ATOM 24218 O THR M 180 42.237 48.236 73.205 1.00148.09 O +ATOM 24219 CB THR M 180 39.192 48.748 73.918 1.00122.98 C +ATOM 24220 OG1 THR M 180 39.519 50.035 73.383 1.00137.86 O +ATOM 24221 CG2 THR M 180 39.628 48.674 75.385 1.00136.05 C +ATOM 24222 N ILE M 181 41.173 48.518 71.218 1.00102.12 N +ATOM 24223 CA ILE M 181 42.361 49.036 70.534 1.00 99.72 C +ATOM 24224 C ILE M 181 42.300 50.560 70.402 1.00119.58 C +ATOM 24225 O ILE M 181 41.374 51.107 69.789 1.00114.46 O +ATOM 24226 CB ILE M 181 42.518 48.420 69.136 1.00100.83 C +ATOM 24227 CG1 ILE M 181 42.485 46.893 69.211 1.00 94.32 C +ATOM 24228 CG2 ILE M 181 43.824 48.849 68.480 1.00 98.76 C +ATOM 24229 CD1 ILE M 181 41.340 46.273 68.427 1.00100.02 C +ATOM 24230 N LEU M 182 43.265 51.243 71.030 1.00134.68 N +ATOM 24231 CA LEU M 182 43.290 52.719 71.096 1.00136.15 C +ATOM 24232 C LEU M 182 44.118 53.372 69.990 1.00120.30 C +ATOM 24233 O LEU M 182 45.209 52.913 69.665 1.00 86.03 O +ATOM 24234 CB LEU M 182 43.837 53.183 72.445 1.00116.18 C +ATOM 24235 CG LEU M 182 43.940 54.702 72.630 1.00104.02 C +ATOM 24236 CD1 LEU M 182 42.588 55.407 72.563 1.00 98.37 C +ATOM 24237 CD2 LEU M 182 44.637 54.970 73.951 1.00 97.69 C +ATOM 24238 N SER M 183 43.585 54.466 69.451 1.00131.73 N +ATOM 24239 CA SER M 183 44.283 55.263 68.458 1.00134.84 C +ATOM 24240 C SER M 183 44.058 56.749 68.741 1.00106.42 C +ATOM 24241 O SER M 183 42.943 57.151 69.090 1.00 71.11 O +ATOM 24242 CB SER M 183 43.785 54.904 67.046 1.00161.66 C +ATOM 24243 OG SER M 183 43.528 53.514 66.928 1.00135.08 O +ATOM 24244 N TYR M 184 45.097 57.555 68.546 1.00 88.34 N +ATOM 24245 CA TYR M 184 44.968 58.995 68.709 1.00 90.50 C +ATOM 24246 C TYR M 184 45.949 59.815 67.868 1.00106.63 C +ATOM 24247 O TYR M 184 47.036 59.362 67.495 1.00 88.81 O +ATOM 24248 CB TYR M 184 45.059 59.393 70.195 1.00 82.95 C +ATOM 24249 CG TYR M 184 46.333 58.991 70.892 1.00 73.93 C +ATOM 24250 CD1 TYR M 184 47.461 59.779 70.823 1.00 85.64 C +ATOM 24251 CD2 TYR M 184 46.409 57.821 71.618 1.00 81.43 C +ATOM 24252 CE1 TYR M 184 48.648 59.388 71.424 1.00105.06 C +ATOM 24253 CE2 TYR M 184 47.593 57.412 72.217 1.00 99.49 C +ATOM 24254 CZ TYR M 184 48.713 58.196 72.117 1.00104.23 C +ATOM 24255 OH TYR M 184 49.891 57.794 72.720 1.00109.64 O +ATOM 24256 N GLU M 185 45.546 61.056 67.606 1.00123.70 N +ATOM 24257 CA GLU M 185 46.312 62.004 66.795 1.00142.32 C +ATOM 24258 C GLU M 185 46.358 63.350 67.494 1.00139.50 C +ATOM 24259 O GLU M 185 45.353 64.049 67.561 1.00148.23 O +ATOM 24260 CB GLU M 185 45.730 62.204 65.381 1.00149.97 C +ATOM 24261 CG GLU M 185 45.240 60.953 64.678 1.00179.88 C +ATOM 24262 CD GLU M 185 44.867 61.241 63.229 1.00170.67 C +ATOM 24263 OE1 GLU M 185 44.967 62.407 62.802 1.00113.14 O +ATOM 24264 OE2 GLU M 185 44.526 60.283 62.511 1.00185.12 O +ATOM 24265 N VAL M 186 47.557 63.740 67.905 1.00140.38 N +ATOM 24266 CA VAL M 186 47.792 65.049 68.482 1.00135.61 C +ATOM 24267 C VAL M 186 48.469 65.962 67.458 1.00147.56 C +ATOM 24268 O VAL M 186 49.355 65.533 66.717 1.00108.13 O +ATOM 24269 CB VAL M 186 48.675 64.932 69.729 1.00155.53 C +ATOM 24270 CG1 VAL M 186 48.750 66.265 70.454 1.00168.74 C +ATOM 24271 CG2 VAL M 186 48.140 63.850 70.656 1.00168.19 C +ATOM 24272 N GLN M 187 48.039 67.222 67.415 1.00172.01 N +ATOM 24273 CA GLN M 187 48.551 68.172 66.423 1.00160.33 C +ATOM 24274 C GLN M 187 48.564 69.593 66.955 1.00135.62 C +ATOM 24275 O GLN M 187 47.614 70.020 67.611 1.00108.51 O +ATOM 24276 CB GLN M 187 47.670 68.139 65.172 1.00154.51 C +ATOM 24277 CG GLN M 187 48.024 67.078 64.154 1.00170.53 C +ATOM 24278 CD GLN M 187 46.864 66.775 63.224 1.00213.61 C +ATOM 24279 OE1 GLN M 187 46.131 67.684 62.820 1.00178.77 O +ATOM 24280 NE2 GLN M 187 46.668 65.491 62.904 1.00246.44 N +ATOM 24281 N ALA M 188 49.636 70.317 66.653 1.00124.41 N +ATOM 24282 CA ALA M 188 49.733 71.716 67.034 1.00140.71 C +ATOM 24283 C ALA M 188 50.420 72.516 65.939 1.00132.27 C +ATOM 24284 O ALA M 188 51.367 72.045 65.323 1.00 93.87 O +ATOM 24285 CB ALA M 188 50.481 71.858 68.352 1.00156.51 C +ATOM 24286 N GLY M 189 49.921 73.720 65.689 1.00140.33 N +ATOM 24287 CA GLY M 189 50.477 74.573 64.652 1.00151.25 C +ATOM 24288 C GLY M 189 50.430 76.050 64.996 1.00150.13 C +ATOM 24289 O GLY M 189 49.442 76.532 65.543 1.00118.86 O +ATOM 24290 N VAL M 190 51.508 76.761 64.675 1.00167.36 N +ATOM 24291 CA VAL M 190 51.580 78.200 64.884 1.00174.97 C +ATOM 24292 C VAL M 190 51.683 78.911 63.532 1.00190.22 C +ATOM 24293 O VAL M 190 52.444 78.494 62.651 1.00152.65 O +ATOM 24294 CB VAL M 190 52.784 78.582 65.770 1.00176.63 C +ATOM 24295 CG1 VAL M 190 52.692 80.042 66.186 1.00156.21 C +ATOM 24296 CG2 VAL M 190 52.870 77.668 66.991 1.00163.61 C +ATOM 24297 N PHE M 191 50.910 79.980 63.368 1.00214.69 N +ATOM 24298 CA PHE M 191 50.774 80.638 62.065 1.00222.88 C +ATOM 24299 C PHE M 191 50.889 82.156 62.221 1.00185.07 C +ATOM 24300 O PHE M 191 50.230 82.738 63.086 1.00146.04 O +ATOM 24301 CB PHE M 191 49.423 80.261 61.429 1.00227.49 C +ATOM 24302 CG PHE M 191 49.382 80.438 59.932 1.00215.38 C +ATOM 24303 CD1 PHE M 191 49.357 81.705 59.373 1.00197.57 C +ATOM 24304 CD2 PHE M 191 49.365 79.337 59.084 1.00201.31 C +ATOM 24305 CE1 PHE M 191 49.308 81.871 57.999 1.00173.94 C +ATOM 24306 CE2 PHE M 191 49.325 79.499 57.709 1.00173.80 C +ATOM 24307 CZ PHE M 191 49.291 80.768 57.165 1.00150.52 C +ATOM 24308 N LEU M 200 55.451 83.224 58.800 1.00139.12 N +ATOM 24309 CA LEU M 200 55.799 82.211 59.789 1.00149.33 C +ATOM 24310 C LEU M 200 54.690 81.176 59.923 1.00193.92 C +ATOM 24311 O LEU M 200 53.596 81.472 60.436 1.00193.31 O +ATOM 24312 CB LEU M 200 56.077 82.806 61.179 1.00139.76 C +ATOM 24313 CG LEU M 200 56.269 81.751 62.284 1.00131.24 C +ATOM 24314 CD1 LEU M 200 57.752 81.564 62.570 1.00118.37 C +ATOM 24315 CD2 LEU M 200 55.485 82.057 63.564 1.00110.81 C +ATOM 24316 N GLU M 201 54.989 79.957 59.482 1.00199.80 N +ATOM 24317 CA GLU M 201 54.213 78.786 59.873 1.00167.10 C +ATOM 24318 C GLU M 201 55.116 77.784 60.573 1.00137.91 C +ATOM 24319 O GLU M 201 56.296 77.673 60.248 1.00120.57 O +ATOM 24320 CB GLU M 201 53.550 78.141 58.654 1.00170.51 C +ATOM 24321 CG GLU M 201 52.386 77.237 59.027 1.00180.27 C +ATOM 24322 CD GLU M 201 51.713 76.591 57.827 1.00191.95 C +ATOM 24323 OE1 GLU M 201 51.365 77.314 56.869 1.00217.55 O +ATOM 24324 OE2 GLU M 201 51.527 75.356 57.843 1.00203.82 O +ATOM 24325 N GLY M 202 54.558 77.057 61.532 1.00123.72 N +ATOM 24326 CA GLY M 202 55.256 75.945 62.164 1.00153.06 C +ATOM 24327 C GLY M 202 54.290 74.900 62.691 1.00167.53 C +ATOM 24328 O GLY M 202 53.367 75.228 63.440 1.00204.56 O +ATOM 24329 N GLU M 203 54.487 73.640 62.296 1.00142.95 N +ATOM 24330 CA GLU M 203 53.568 72.574 62.675 1.00113.47 C +ATOM 24331 C GLU M 203 54.261 71.343 63.253 1.00110.71 C +ATOM 24332 O GLU M 203 55.269 70.870 62.726 1.00 87.42 O +ATOM 24333 CB GLU M 203 52.716 72.162 61.478 1.00122.35 C +ATOM 24334 CG GLU M 203 51.754 73.255 61.013 1.00132.15 C +ATOM 24335 CD GLU M 203 50.811 72.831 59.889 1.00145.39 C +ATOM 24336 OE1 GLU M 203 50.985 71.715 59.353 1.00149.77 O +ATOM 24337 OE2 GLU M 203 49.911 73.629 59.533 1.00138.78 O +ATOM 24338 N VAL M 204 53.694 70.836 64.347 1.00118.91 N +ATOM 24339 CA VAL M 204 54.100 69.565 64.941 1.00110.10 C +ATOM 24340 C VAL M 204 52.898 68.641 65.023 1.00115.11 C +ATOM 24341 O VAL M 204 51.780 69.061 65.355 1.00118.21 O +ATOM 24342 CB VAL M 204 54.677 69.769 66.349 1.00107.17 C +ATOM 24343 CG1 VAL M 204 54.754 68.457 67.115 1.00110.80 C +ATOM 24344 CG2 VAL M 204 56.053 70.411 66.243 1.00116.45 C +ATOM 24345 N GLY M 205 53.115 67.392 64.632 1.00125.37 N +ATOM 24346 CA GLY M 205 52.061 66.384 64.664 1.00134.55 C +ATOM 24347 C GLY M 205 52.582 65.056 65.187 1.00122.12 C +ATOM 24348 O GLY M 205 53.759 64.724 64.999 1.00 97.78 O +ATOM 24349 N TYR M 206 51.700 64.292 65.821 1.00109.86 N +ATOM 24350 CA TYR M 206 52.033 62.946 66.274 1.00120.89 C +ATOM 24351 C TYR M 206 50.791 62.064 66.245 1.00131.21 C +ATOM 24352 O TYR M 206 49.703 62.522 66.579 1.00130.00 O +ATOM 24353 CB TYR M 206 52.598 62.988 67.699 1.00135.76 C +ATOM 24354 CG TYR M 206 52.902 61.626 68.274 1.00134.25 C +ATOM 24355 CD1 TYR M 206 54.016 60.912 67.868 1.00125.23 C +ATOM 24356 CD2 TYR M 206 52.050 61.040 69.207 1.00144.34 C +ATOM 24357 CE1 TYR M 206 54.272 59.646 68.366 1.00129.53 C +ATOM 24358 CE2 TYR M 206 52.299 59.777 69.709 1.00126.46 C +ATOM 24359 CZ TYR M 206 53.403 59.082 69.285 1.00114.28 C +ATOM 24360 OH TYR M 206 53.670 57.847 69.819 1.00 97.04 O +ATOM 24361 N THR M 207 50.954 60.797 65.869 1.00135.58 N +ATOM 24362 CA THR M 207 49.831 59.852 65.839 1.00135.26 C +ATOM 24363 C THR M 207 50.243 58.478 66.359 1.00113.53 C +ATOM 24364 O THR M 207 51.340 57.987 66.054 1.00109.14 O +ATOM 24365 CB THR M 207 49.271 59.673 64.414 1.00162.32 C +ATOM 24366 OG1 THR M 207 50.287 59.133 63.562 1.00206.22 O +ATOM 24367 CG2 THR M 207 48.806 60.996 63.838 1.00178.72 C +ATOM 24368 N SER M 208 49.370 57.861 67.151 1.00 95.98 N +ATOM 24369 CA SER M 208 49.678 56.551 67.729 1.00 99.84 C +ATOM 24370 C SER M 208 48.507 55.585 67.655 1.00 77.31 C +ATOM 24371 O SER M 208 47.412 55.895 68.118 1.00 49.80 O +ATOM 24372 CB SER M 208 50.146 56.679 69.193 1.00108.67 C +ATOM 24373 OG SER M 208 50.312 55.406 69.792 1.00113.74 O +ATOM 24374 N ASN M 209 48.782 54.405 67.101 1.00 86.42 N +ATOM 24375 CA ASN M 209 47.830 53.292 67.068 1.00 97.55 C +ATOM 24376 C ASN M 209 48.352 52.163 67.925 1.00 91.35 C +ATOM 24377 O ASN M 209 49.540 51.813 67.867 1.00 85.19 O +ATOM 24378 CB ASN M 209 47.652 52.721 65.646 1.00 90.80 C +ATOM 24379 CG ASN M 209 46.884 53.618 64.724 1.00 94.96 C +ATOM 24380 OD1 ASN M 209 45.663 53.725 64.807 1.00101.04 O +ATOM 24381 ND2 ASN M 209 47.610 54.350 63.889 1.00122.53 N +ATOM 24382 N GLU M 210 47.455 51.552 68.683 1.00 97.00 N +ATOM 24383 CA GLU M 210 47.779 50.288 69.342 1.00105.70 C +ATOM 24384 C GLU M 210 47.881 49.216 68.274 1.00 92.81 C +ATOM 24385 O GLU M 210 47.150 49.249 67.303 1.00 73.45 O +ATOM 24386 CB GLU M 210 46.692 49.908 70.352 1.00113.01 C +ATOM 24387 CG GLU M 210 47.203 49.369 71.688 1.00104.12 C +ATOM 24388 CD GLU M 210 46.141 49.425 72.785 1.00 94.53 C +ATOM 24389 OE1 GLU M 210 45.180 50.253 72.712 1.00 58.31 O +ATOM 24390 OE2 GLU M 210 46.228 48.571 73.687 1.00 85.81 O +ATOM 24391 N PRO M 211 48.842 48.294 68.415 1.00113.01 N +ATOM 24392 CA PRO M 211 48.893 47.180 67.484 1.00109.25 C +ATOM 24393 C PRO M 211 47.770 46.190 67.757 1.00 92.60 C +ATOM 24394 O PRO M 211 47.598 45.729 68.891 1.00 70.33 O +ATOM 24395 CB PRO M 211 50.260 46.548 67.754 1.00128.81 C +ATOM 24396 CG PRO M 211 51.051 47.585 68.470 1.00149.21 C +ATOM 24397 CD PRO M 211 50.034 48.338 69.278 1.00149.88 C +ATOM 24398 N VAL M 212 46.970 45.930 66.726 1.00 96.97 N +ATOM 24399 CA VAL M 212 45.857 44.991 66.818 1.00107.21 C +ATOM 24400 C VAL M 212 46.437 43.606 67.147 1.00111.56 C +ATOM 24401 O VAL M 212 45.882 42.848 67.944 1.00 73.28 O +ATOM 24402 CB VAL M 212 45.045 44.927 65.489 1.00 94.46 C +ATOM 24403 CG1 VAL M 212 43.827 44.017 65.660 1.00 82.57 C +ATOM 24404 CG2 VAL M 212 44.633 46.324 65.012 1.00 67.13 C +ATOM 24405 N MET M 213 47.542 43.300 66.471 1.00127.83 N +ATOM 24406 CA MET M 213 48.460 42.192 66.775 1.00116.29 C +ATOM 24407 C MET M 213 48.653 41.933 68.270 1.00118.28 C +ATOM 24408 O MET M 213 48.443 40.819 68.779 1.00108.76 O +ATOM 24409 CB MET M 213 49.788 42.611 66.151 1.00 98.15 C +ATOM 24410 CG MET M 213 50.922 41.626 66.205 1.00 78.84 C +ATOM 24411 SD MET M 213 52.296 42.411 65.324 1.00 58.99 S +ATOM 24412 CE MET M 213 53.289 42.677 66.797 1.00 99.39 C +ATOM 24413 N LEU M 214 48.927 43.015 68.983 1.00121.65 N +ATOM 24414 CA LEU M 214 49.356 42.934 70.371 1.00120.18 C +ATOM 24415 C LEU M 214 48.147 42.854 71.306 1.00101.41 C +ATOM 24416 O LEU M 214 48.206 42.228 72.378 1.00101.89 O +ATOM 24417 CB LEU M 214 50.206 44.156 70.717 1.00126.01 C +ATOM 24418 CG LEU M 214 51.513 43.950 71.503 1.00103.63 C +ATOM 24419 CD1 LEU M 214 52.512 43.021 70.799 1.00 67.28 C +ATOM 24420 CD2 LEU M 214 52.120 45.334 71.782 1.00105.94 C +ATOM 24421 N CYS M 215 47.038 43.455 70.878 1.00 78.01 N +ATOM 24422 CA CYS M 215 45.768 43.344 71.606 1.00 92.65 C +ATOM 24423 C CYS M 215 45.166 41.931 71.518 1.00103.48 C +ATOM 24424 O CYS M 215 44.637 41.382 72.520 1.00104.42 O +ATOM 24425 CB CYS M 215 44.748 44.322 71.051 1.00 81.76 C +ATOM 24426 SG CYS M 215 45.224 46.031 71.244 1.00 82.80 S +ATOM 24427 N LEU M 216 45.230 41.362 70.314 1.00 83.41 N +ATOM 24428 CA LEU M 216 44.843 39.990 70.124 1.00 68.68 C +ATOM 24429 C LEU M 216 45.634 39.108 71.102 1.00 57.30 C +ATOM 24430 O LEU M 216 45.062 38.254 71.806 1.00 57.19 O +ATOM 24431 CB LEU M 216 45.067 39.561 68.683 1.00 66.91 C +ATOM 24432 CG LEU M 216 44.722 38.098 68.375 1.00 76.56 C +ATOM 24433 CD1 LEU M 216 43.278 37.760 68.708 1.00 88.43 C +ATOM 24434 CD2 LEU M 216 44.988 37.784 66.912 1.00 77.00 C +ATOM 24435 N MET M 217 46.939 39.322 71.157 1.00 55.86 N +ATOM 24436 CA MET M 217 47.793 38.458 71.948 1.00 88.61 C +ATOM 24437 C MET M 217 47.393 38.574 73.412 1.00 77.54 C +ATOM 24438 O MET M 217 47.272 37.559 74.117 1.00 93.86 O +ATOM 24439 CB MET M 217 49.285 38.790 71.728 1.00108.13 C +ATOM 24440 CG MET M 217 50.187 37.551 71.598 1.00118.25 C +ATOM 24441 SD MET M 217 50.367 36.637 73.148 1.00 96.79 S +ATOM 24442 CE MET M 217 51.187 35.141 72.635 1.00116.26 C +ATOM 24443 N SER M 218 47.215 39.808 73.861 1.00 71.49 N +ATOM 24444 CA SER M 218 46.867 40.095 75.259 1.00 75.48 C +ATOM 24445 C SER M 218 45.586 39.366 75.641 1.00 72.12 C +ATOM 24446 O SER M 218 45.520 38.687 76.674 1.00 63.05 O +ATOM 24447 CB SER M 218 46.695 41.611 75.457 1.00 62.93 C +ATOM 24448 OG SER M 218 46.538 41.917 76.822 1.00 56.39 O +ATOM 24449 N ALA M 219 44.588 39.481 74.779 1.00 73.86 N +ATOM 24450 CA ALA M 219 43.272 38.938 75.083 1.00 94.23 C +ATOM 24451 C ALA M 219 43.286 37.406 75.137 1.00 78.77 C +ATOM 24452 O ALA M 219 42.588 36.785 75.948 1.00 86.59 O +ATOM 24453 CB ALA M 219 42.269 39.437 74.056 1.00110.34 C +ATOM 24454 N ILE M 220 44.131 36.802 74.317 1.00 68.82 N +ATOM 24455 CA ILE M 220 44.263 35.345 74.314 1.00 69.75 C +ATOM 24456 C ILE M 220 44.903 34.854 75.614 1.00 75.70 C +ATOM 24457 O ILE M 220 44.468 33.860 76.188 1.00 69.11 O +ATOM 24458 CB ILE M 220 45.083 34.846 73.090 1.00 66.76 C +ATOM 24459 CG1 ILE M 220 44.259 35.074 71.801 1.00 77.38 C +ATOM 24460 CG2 ILE M 220 45.453 33.374 73.238 1.00 48.85 C +ATOM 24461 CD1 ILE M 220 45.057 35.009 70.521 1.00 66.97 C +ATOM 24462 N GLU M 221 45.919 35.566 76.084 1.00 81.03 N +ATOM 24463 CA GLU M 221 46.549 35.243 77.369 1.00 81.48 C +ATOM 24464 C GLU M 221 45.518 35.271 78.491 1.00 80.06 C +ATOM 24465 O GLU M 221 45.395 34.325 79.269 1.00 80.53 O +ATOM 24466 CB GLU M 221 47.677 36.242 77.664 1.00100.03 C +ATOM 24467 CG GLU M 221 48.921 36.025 76.812 1.00133.23 C +ATOM 24468 CD GLU M 221 49.873 37.222 76.793 1.00152.01 C +ATOM 24469 OE1 GLU M 221 49.405 38.397 76.784 1.00 92.63 O +ATOM 24470 OE2 GLU M 221 51.098 36.957 76.728 1.00172.79 O +ATOM 24471 N THR M 222 44.782 36.380 78.558 1.00 81.66 N +ATOM 24472 CA THR M 222 43.714 36.581 79.539 1.00 72.82 C +ATOM 24473 C THR M 222 42.743 35.414 79.528 1.00 70.62 C +ATOM 24474 O THR M 222 42.386 34.873 80.574 1.00 75.65 O +ATOM 24475 CB THR M 222 42.928 37.873 79.212 1.00 71.61 C +ATOM 24476 OG1 THR M 222 43.730 39.032 79.505 1.00 61.21 O +ATOM 24477 CG2 THR M 222 41.595 37.921 79.986 1.00 76.40 C +ATOM 24478 N GLY M 223 42.298 35.052 78.335 1.00 77.10 N +ATOM 24479 CA GLY M 223 41.443 33.883 78.154 1.00102.92 C +ATOM 24480 C GLY M 223 42.038 32.600 78.737 1.00 98.02 C +ATOM 24481 O GLY M 223 41.312 31.785 79.323 1.00 95.47 O +ATOM 24482 N VAL M 224 43.346 32.409 78.556 1.00 76.37 N +ATOM 24483 CA VAL M 224 43.986 31.204 79.030 1.00 74.51 C +ATOM 24484 C VAL M 224 43.913 31.176 80.543 1.00 85.26 C +ATOM 24485 O VAL M 224 43.658 30.137 81.148 1.00102.06 O +ATOM 24486 CB VAL M 224 45.449 31.131 78.578 1.00 80.58 C +ATOM 24487 CG1 VAL M 224 46.153 29.972 79.265 1.00 83.30 C +ATOM 24488 CG2 VAL M 224 45.530 30.972 77.061 1.00 97.90 C +ATOM 24489 N ILE M 225 44.137 32.331 81.165 1.00101.64 N +ATOM 24490 CA ILE M 225 44.067 32.426 82.627 1.00 95.11 C +ATOM 24491 C ILE M 225 42.674 32.057 83.121 1.00 92.48 C +ATOM 24492 O ILE M 225 42.542 31.185 83.972 1.00 76.61 O +ATOM 24493 CB ILE M 225 44.444 33.827 83.139 1.00 78.54 C +ATOM 24494 CG1 ILE M 225 45.930 34.084 82.906 1.00 77.10 C +ATOM 24495 CG2 ILE M 225 44.158 33.933 84.622 1.00 85.19 C +ATOM 24496 CD1 ILE M 225 46.314 35.544 82.978 1.00 86.99 C +ATOM 24497 N PHE M 226 41.648 32.705 82.569 1.00108.39 N +ATOM 24498 CA PHE M 226 40.252 32.398 82.924 1.00120.13 C +ATOM 24499 C PHE M 226 39.962 30.897 82.749 1.00114.50 C +ATOM 24500 O PHE M 226 39.140 30.344 83.491 1.00151.26 O +ATOM 24501 CB PHE M 226 39.237 33.235 82.104 1.00107.28 C +ATOM 24502 CG PHE M 226 39.036 34.644 82.600 1.00 96.22 C +ATOM 24503 CD1 PHE M 226 38.587 34.893 83.873 1.00 93.45 C +ATOM 24504 CD2 PHE M 226 39.279 35.733 81.754 1.00105.13 C +ATOM 24505 CE1 PHE M 226 38.440 36.200 84.324 1.00 98.62 C +ATOM 24506 CE2 PHE M 226 39.113 37.039 82.192 1.00 85.70 C +ATOM 24507 CZ PHE M 226 38.712 37.272 83.485 1.00 92.14 C +ATOM 24508 N LEU M 227 40.597 30.252 81.763 1.00 78.02 N +ATOM 24509 CA LEU M 227 40.375 28.818 81.525 1.00 74.19 C +ATOM 24510 C LEU M 227 40.943 28.039 82.654 1.00 72.57 C +ATOM 24511 O LEU M 227 40.328 27.081 83.118 1.00 84.49 O +ATOM 24512 CB LEU M 227 41.059 28.316 80.258 1.00 89.96 C +ATOM 24513 CG LEU M 227 40.193 27.746 79.134 1.00105.39 C +ATOM 24514 CD1 LEU M 227 38.882 28.441 79.189 1.00103.03 C +ATOM 24515 CD2 LEU M 227 40.718 27.782 77.699 1.00126.69 C +ATOM 24516 N ILE M 228 42.152 28.403 83.058 1.00 72.97 N +ATOM 24517 CA ILE M 228 42.854 27.653 84.094 1.00 93.65 C +ATOM 24518 C ILE M 228 42.105 27.796 85.408 1.00 87.75 C +ATOM 24519 O ILE M 228 41.838 26.815 86.096 1.00 68.50 O +ATOM 24520 CB ILE M 228 44.310 28.133 84.297 1.00102.60 C +ATOM 24521 CG1 ILE M 228 45.156 27.864 83.048 1.00116.31 C +ATOM 24522 CG2 ILE M 228 44.940 27.398 85.461 1.00 99.75 C +ATOM 24523 CD1 ILE M 228 46.471 28.612 83.010 1.00108.93 C +ATOM 24524 N ASN M 229 41.757 29.028 85.737 1.00 96.39 N +ATOM 24525 CA ASN M 229 41.028 29.308 86.964 1.00106.02 C +ATOM 24526 C ASN M 229 39.703 28.547 86.981 1.00112.45 C +ATOM 24527 O ASN M 229 39.319 27.965 87.998 1.00135.89 O +ATOM 24528 CB ASN M 229 40.794 30.822 87.096 1.00109.53 C +ATOM 24529 CG ASN M 229 40.412 31.237 88.493 1.00 98.43 C +ATOM 24530 OD1 ASN M 229 40.718 30.545 89.472 1.00101.91 O +ATOM 24531 ND2 ASN M 229 39.758 32.390 88.602 1.00 82.37 N +ATOM 24532 N ASP M 230 39.000 28.564 85.848 1.00116.07 N +ATOM 24533 CA ASP M 230 37.712 27.882 85.714 1.00112.97 C +ATOM 24534 C ASP M 230 37.884 26.385 85.893 1.00 98.54 C +ATOM 24535 O ASP M 230 37.088 25.741 86.598 1.00104.03 O +ATOM 24536 CB ASP M 230 37.100 28.156 84.342 1.00122.97 C +ATOM 24537 CG ASP M 230 35.711 27.572 84.201 1.00144.17 C +ATOM 24538 OD1 ASP M 230 34.779 28.128 84.809 1.00182.30 O +ATOM 24539 OD2 ASP M 230 35.540 26.560 83.504 1.00161.96 O +ATOM 24540 N GLY M 231 38.963 25.854 85.331 1.00 74.88 N +ATOM 24541 CA GLY M 231 39.261 24.453 85.488 1.00 90.96 C +ATOM 24542 C GLY M 231 39.627 24.057 86.917 1.00107.21 C +ATOM 24543 O GLY M 231 39.280 22.950 87.389 1.00126.37 O +ATOM 24544 N ILE M 232 40.296 24.964 87.624 1.00117.41 N +ATOM 24545 CA ILE M 232 40.610 24.760 89.046 1.00115.98 C +ATOM 24546 C ILE M 232 39.336 24.649 89.889 1.00105.94 C +ATOM 24547 O ILE M 232 39.166 23.684 90.627 1.00105.22 O +ATOM 24548 CB ILE M 232 41.479 25.910 89.596 1.00119.69 C +ATOM 24549 CG1 ILE M 232 42.904 25.790 89.050 1.00108.80 C +ATOM 24550 CG2 ILE M 232 41.484 25.905 91.119 1.00137.60 C +ATOM 24551 CD1 ILE M 232 43.713 27.057 89.180 1.00105.47 C +ATOM 24552 N ASP M 233 38.430 25.614 89.727 1.00110.63 N +ATOM 24553 CA ASP M 233 37.114 25.582 90.377 1.00100.27 C +ATOM 24554 C ASP M 233 36.373 24.268 90.086 1.00100.63 C +ATOM 24555 O ASP M 233 35.855 23.633 90.992 1.00 83.76 O +ATOM 24556 CB ASP M 233 36.242 26.766 89.907 1.00119.72 C +ATOM 24557 CG ASP M 233 36.796 28.119 90.332 1.00125.51 C +ATOM 24558 OD1 ASP M 233 37.976 28.167 90.780 1.00170.78 O +ATOM 24559 OD2 ASP M 233 36.089 29.137 90.126 1.00 80.12 O +ATOM 24560 N ARG M 234 36.302 23.877 88.812 1.00 98.11 N +ATOM 24561 CA ARG M 234 35.466 22.747 88.398 1.00 95.13 C +ATOM 24562 C ARG M 234 36.107 21.382 88.628 1.00 90.03 C +ATOM 24563 O ARG M 234 35.522 20.352 88.297 1.00104.15 O +ATOM 24564 CB ARG M 234 35.049 22.918 86.926 1.00 95.42 C +ATOM 24565 CG ARG M 234 33.995 23.994 86.750 1.00 80.33 C +ATOM 24566 CD ARG M 234 33.940 24.527 85.352 1.00 73.76 C +ATOM 24567 NE ARG M 234 32.964 25.604 85.303 1.00 94.45 N +ATOM 24568 CZ ARG M 234 31.905 25.633 84.499 1.00116.99 C +ATOM 24569 NH1 ARG M 234 31.688 24.635 83.653 1.00150.13 N +ATOM 24570 NH2 ARG M 234 31.073 26.675 84.514 1.00 99.14 N +ATOM 24571 N GLY M 235 37.333 21.376 89.132 1.00 97.66 N +ATOM 24572 CA GLY M 235 38.036 20.128 89.399 1.00103.96 C +ATOM 24573 C GLY M 235 38.538 19.408 88.150 1.00122.10 C +ATOM 24574 O GLY M 235 38.620 18.182 88.141 1.00121.52 O +ATOM 24575 N LEU M 236 38.933 20.157 87.113 1.00135.80 N +ATOM 24576 CA LEU M 236 39.689 19.566 85.985 1.00112.69 C +ATOM 24577 C LEU M 236 41.119 19.279 86.419 1.00119.22 C +ATOM 24578 O LEU M 236 41.636 18.175 86.222 1.00151.57 O +ATOM 24579 CB LEU M 236 39.726 20.487 84.765 1.00120.17 C +ATOM 24580 CG LEU M 236 38.516 20.464 83.821 1.00151.53 C +ATOM 24581 CD1 LEU M 236 37.366 21.274 84.407 1.00179.33 C +ATOM 24582 CD2 LEU M 236 38.903 21.022 82.459 1.00160.70 C +ATOM 24583 N TRP M 237 41.745 20.261 87.056 1.00120.76 N +ATOM 24584 CA TRP M 237 43.130 20.131 87.514 1.00131.80 C +ATOM 24585 C TRP M 237 43.299 20.773 88.907 1.00134.64 C +ATOM 24586 O TRP M 237 42.441 21.531 89.358 1.00107.94 O +ATOM 24587 CB TRP M 237 44.086 20.756 86.487 1.00117.32 C +ATOM 24588 CG TRP M 237 43.510 21.935 85.798 1.00 99.73 C +ATOM 24589 CD1 TRP M 237 43.221 23.142 86.357 1.00103.73 C +ATOM 24590 CD2 TRP M 237 43.114 22.021 84.431 1.00 88.51 C +ATOM 24591 NE1 TRP M 237 42.665 23.972 85.424 1.00127.22 N +ATOM 24592 CE2 TRP M 237 42.613 23.315 84.224 1.00110.18 C +ATOM 24593 CE3 TRP M 237 43.128 21.133 83.362 1.00 91.68 C +ATOM 24594 CZ2 TRP M 237 42.137 23.750 82.983 1.00103.74 C +ATOM 24595 CZ3 TRP M 237 42.653 21.572 82.122 1.00100.68 C +ATOM 24596 CH2 TRP M 237 42.162 22.865 81.950 1.00 94.55 C +ATOM 24597 N ASP M 238 44.410 20.464 89.571 1.00125.45 N +ATOM 24598 CA ASP M 238 44.623 20.884 90.954 1.00105.58 C +ATOM 24599 C ASP M 238 45.960 21.580 91.166 1.00 95.37 C +ATOM 24600 O ASP M 238 46.973 21.241 90.517 1.00100.96 O +ATOM 24601 CB ASP M 238 44.516 19.685 91.885 1.00120.78 C +ATOM 24602 CG ASP M 238 43.184 18.968 91.757 1.00130.38 C +ATOM 24603 OD1 ASP M 238 43.047 18.160 90.812 1.00142.83 O +ATOM 24604 OD2 ASP M 238 42.292 19.177 92.614 1.00129.78 O +ATOM 24605 N LEU M 239 45.967 22.529 92.099 1.00 75.54 N +ATOM 24606 CA LEU M 239 47.176 23.253 92.440 1.00 84.32 C +ATOM 24607 C LEU M 239 48.143 22.394 93.262 1.00102.21 C +ATOM 24608 O LEU M 239 47.731 21.572 94.085 1.00102.39 O +ATOM 24609 CB LEU M 239 46.833 24.510 93.232 1.00 91.07 C +ATOM 24610 CG LEU M 239 46.253 25.722 92.507 1.00105.01 C +ATOM 24611 CD1 LEU M 239 46.082 26.900 93.458 1.00100.19 C +ATOM 24612 CD2 LEU M 239 47.138 26.124 91.349 1.00121.61 C +ATOM 24613 N GLN M 240 49.437 22.605 93.038 1.00113.59 N +ATOM 24614 CA GLN M 240 50.471 22.017 93.878 1.00107.66 C +ATOM 24615 C GLN M 240 50.221 22.386 95.336 1.00113.84 C +ATOM 24616 O GLN M 240 50.105 21.519 96.198 1.00110.00 O +ATOM 24617 CB GLN M 240 51.860 22.509 93.432 1.00112.13 C +ATOM 24618 CG GLN M 240 53.014 21.800 94.124 1.00114.18 C +ATOM 24619 CD GLN M 240 53.065 20.323 93.760 1.00126.82 C +ATOM 24620 OE1 GLN M 240 53.584 19.950 92.708 1.00139.43 O +ATOM 24621 NE2 GLN M 240 52.528 19.476 94.632 1.00135.27 N +ATOM 24622 N ASN M 241 50.158 23.688 95.595 1.00149.45 N +ATOM 24623 CA ASN M 241 49.917 24.220 96.936 1.00160.78 C +ATOM 24624 C ASN M 241 48.494 24.719 97.069 1.00159.48 C +ATOM 24625 O ASN M 241 48.128 25.751 96.472 1.00179.17 O +ATOM 24626 CB ASN M 241 50.867 25.384 97.213 1.00183.30 C +ATOM 24627 CG ASN M 241 52.037 24.983 98.071 1.00183.50 C +ATOM 24628 OD1 ASN M 241 52.048 25.256 99.268 1.00167.70 O +ATOM 24629 ND2 ASN M 241 53.020 24.306 97.473 1.00189.90 N +ATOM 24630 N LYS M 242 47.699 24.005 97.860 1.00128.77 N +ATOM 24631 CA LYS M 242 46.301 24.377 98.052 1.00120.59 C +ATOM 24632 C LYS M 242 46.234 25.723 98.762 1.00133.40 C +ATOM 24633 O LYS M 242 45.261 26.476 98.616 1.00104.08 O +ATOM 24634 CB LYS M 242 45.563 23.294 98.839 1.00116.58 C +ATOM 24635 CG LYS M 242 45.773 21.890 98.289 1.00120.43 C +ATOM 24636 CD LYS M 242 44.455 21.190 97.998 1.00139.99 C +ATOM 24637 CE LYS M 242 44.472 20.532 96.625 1.00151.43 C +ATOM 24638 NZ LYS M 242 43.261 19.706 96.370 1.00155.64 N +ATOM 24639 N ALA M 243 47.301 26.016 99.512 1.00172.74 N +ATOM 24640 CA ALA M 243 47.485 27.298 100.189 1.00179.59 C +ATOM 24641 C ALA M 243 47.563 28.445 99.191 1.00184.06 C +ATOM 24642 O ALA M 243 47.386 29.611 99.574 1.00243.93 O +ATOM 24643 CB ALA M 243 48.749 27.266 101.049 1.00163.87 C +ATOM 24644 N GLU M 244 47.855 28.129 97.927 1.00148.55 N +ATOM 24645 CA GLU M 244 48.022 29.168 96.918 1.00142.25 C +ATOM 24646 C GLU M 244 46.731 29.445 96.164 1.00126.07 C +ATOM 24647 O GLU M 244 46.763 30.163 95.178 1.00134.33 O +ATOM 24648 CB GLU M 244 49.142 28.814 95.937 1.00130.33 C +ATOM 24649 CG GLU M 244 50.546 28.937 96.517 1.00136.29 C +ATOM 24650 CD GLU M 244 51.633 28.829 95.465 1.00155.17 C +ATOM 24651 OE1 GLU M 244 51.910 27.701 94.993 1.00179.55 O +ATOM 24652 OE2 GLU M 244 52.199 29.877 95.085 1.00170.67 O +ATOM 24653 N ARG M 245 45.606 28.913 96.646 1.00120.35 N +ATOM 24654 CA ARG M 245 44.285 29.240 96.080 1.00144.31 C +ATOM 24655 C ARG M 245 43.974 30.742 96.089 1.00158.88 C +ATOM 24656 O ARG M 245 43.378 31.253 95.142 1.00166.25 O +ATOM 24657 CB ARG M 245 43.167 28.504 96.820 1.00149.33 C +ATOM 24658 CG ARG M 245 41.738 28.636 96.301 1.00156.46 C +ATOM 24659 CD ARG M 245 41.614 28.093 94.938 1.00159.96 C +ATOM 24660 NE ARG M 245 40.459 28.571 94.136 1.00165.94 N +ATOM 24661 CZ ARG M 245 39.263 27.970 94.114 1.00162.97 C +ATOM 24662 NH1 ARG M 245 39.033 26.801 94.718 1.00141.72 N +ATOM 24663 NH2 ARG M 245 38.286 28.503 93.402 1.00157.70 N +ATOM 24664 N GLN M 246 44.416 31.443 97.133 1.00169.38 N +ATOM 24665 CA GLN M 246 44.130 32.876 97.260 1.00163.69 C +ATOM 24666 C GLN M 246 45.259 33.739 96.686 1.00148.97 C +ATOM 24667 O GLN M 246 45.397 34.905 97.039 1.00151.64 O +ATOM 24668 CB GLN M 246 43.862 33.251 98.724 1.00170.25 C +ATOM 24669 CG GLN M 246 42.551 32.720 99.280 1.00178.91 C +ATOM 24670 CD GLN M 246 42.615 31.240 99.596 1.00226.61 C +ATOM 24671 OE1 GLN M 246 43.588 30.763 100.191 1.00272.18 O +ATOM 24672 NE2 GLN M 246 41.571 30.504 99.221 1.00239.14 N +ATOM 24673 N ASN M 247 46.063 33.152 95.805 1.00142.61 N +ATOM 24674 CA ASN M 247 47.006 33.896 94.966 1.00149.82 C +ATOM 24675 C ASN M 247 46.408 35.195 94.421 1.00164.35 C +ATOM 24676 O ASN M 247 45.248 35.218 93.999 1.00180.95 O +ATOM 24677 CB ASN M 247 47.429 33.028 93.785 1.00138.70 C +ATOM 24678 CG ASN M 247 48.783 33.403 93.247 1.00133.40 C +ATOM 24679 OD1 ASN M 247 48.905 33.947 92.142 1.00159.00 O +ATOM 24680 ND2 ASN M 247 49.819 33.081 94.009 1.00140.99 N +ATOM 24681 N ASP M 248 47.199 36.268 94.430 1.00168.64 N +ATOM 24682 CA ASP M 248 46.724 37.604 94.009 1.00172.48 C +ATOM 24683 C ASP M 248 46.087 37.563 92.620 1.00160.71 C +ATOM 24684 O ASP M 248 45.012 38.130 92.379 1.00154.11 O +ATOM 24685 CB ASP M 248 47.887 38.606 93.983 1.00159.05 C +ATOM 24686 CG ASP M 248 48.380 38.980 95.373 1.00148.42 C +ATOM 24687 OD1 ASP M 248 47.548 39.151 96.285 1.00135.95 O +ATOM 24688 OD2 ASP M 248 49.605 39.149 95.540 1.00140.50 O +ATOM 24689 N ILE M 249 46.775 36.886 91.710 1.00146.43 N +ATOM 24690 CA ILE M 249 46.356 36.817 90.326 1.00143.74 C +ATOM 24691 C ILE M 249 45.061 36.014 90.224 1.00119.16 C +ATOM 24692 O ILE M 249 44.075 36.461 89.607 1.00151.03 O +ATOM 24693 CB ILE M 249 47.459 36.173 89.452 1.00150.07 C +ATOM 24694 CG1 ILE M 249 48.726 37.044 89.459 1.00133.25 C +ATOM 24695 CG2 ILE M 249 46.975 36.007 88.019 1.00189.22 C +ATOM 24696 CD1 ILE M 249 49.985 36.310 89.061 1.00113.76 C +ATOM 24697 N LEU M 250 45.061 34.836 90.835 1.00 93.96 N +ATOM 24698 CA LEU M 250 43.900 33.954 90.777 1.00108.31 C +ATOM 24699 C LEU M 250 42.629 34.605 91.334 1.00134.80 C +ATOM 24700 O LEU M 250 41.525 34.372 90.824 1.00120.29 O +ATOM 24701 CB LEU M 250 44.186 32.652 91.517 1.00 94.15 C +ATOM 24702 CG LEU M 250 45.001 31.626 90.731 1.00 92.10 C +ATOM 24703 CD1 LEU M 250 45.494 30.488 91.613 1.00 91.57 C +ATOM 24704 CD2 LEU M 250 44.181 31.069 89.583 1.00 97.26 C +ATOM 24705 N VAL M 251 42.774 35.369 92.417 1.00157.19 N +ATOM 24706 CA VAL M 251 41.625 36.053 93.029 1.00160.09 C +ATOM 24707 C VAL M 251 41.209 37.279 92.220 1.00152.17 C +ATOM 24708 O VAL M 251 40.050 37.701 92.270 1.00135.04 O +ATOM 24709 CB VAL M 251 41.887 36.471 94.500 1.00146.02 C +ATOM 24710 CG1 VAL M 251 42.298 35.258 95.325 1.00140.22 C +ATOM 24711 CG2 VAL M 251 42.919 37.584 94.589 1.00137.32 C +ATOM 24712 N LYS M 252 42.150 37.835 91.467 1.00145.64 N +ATOM 24713 CA LYS M 252 41.855 38.954 90.583 1.00147.48 C +ATOM 24714 C LYS M 252 40.934 38.502 89.437 1.00156.08 C +ATOM 24715 O LYS M 252 39.918 39.145 89.142 1.00150.39 O +ATOM 24716 CB LYS M 252 43.171 39.540 90.061 1.00141.41 C +ATOM 24717 CG LYS M 252 43.028 40.702 89.094 1.00138.30 C +ATOM 24718 CD LYS M 252 44.404 41.165 88.628 1.00144.07 C +ATOM 24719 CE LYS M 252 44.453 41.342 87.117 1.00166.86 C +ATOM 24720 NZ LYS M 252 45.839 41.534 86.606 1.00161.02 N +ATOM 24721 N TYR M 253 41.271 37.365 88.830 1.00178.70 N +ATOM 24722 CA TYR M 253 40.493 36.822 87.711 1.00185.98 C +ATOM 24723 C TYR M 253 39.222 36.146 88.206 1.00180.73 C +ATOM 24724 O TYR M 253 38.195 36.162 87.513 1.00223.66 O +ATOM 24725 CB TYR M 253 41.337 35.846 86.867 1.00169.41 C +ATOM 24726 CG TYR M 253 42.390 36.561 86.040 1.00146.41 C +ATOM 24727 CD1 TYR M 253 42.077 37.125 84.807 1.00147.34 C +ATOM 24728 CD2 TYR M 253 43.678 36.759 86.540 1.00128.84 C +ATOM 24729 CE1 TYR M 253 43.026 37.836 84.093 1.00157.30 C +ATOM 24730 CE2 TYR M 253 44.636 37.477 85.828 1.00104.16 C +ATOM 24731 CZ TYR M 253 44.303 38.007 84.611 1.00129.49 C +ATOM 24732 OH TYR M 253 45.241 38.692 83.881 1.00130.11 O +ATOM 24733 N ARG M 254 39.274 35.611 89.421 1.00132.41 N +ATOM 24734 CA ARG M 254 38.085 35.081 90.072 1.00146.81 C +ATOM 24735 C ARG M 254 37.102 36.216 90.357 1.00161.34 C +ATOM 24736 O ARG M 254 35.888 36.013 90.351 1.00170.10 O +ATOM 24737 CB ARG M 254 38.456 34.365 91.371 1.00148.05 C +ATOM 24738 CG ARG M 254 37.277 33.725 92.086 1.00145.68 C +ATOM 24739 CD ARG M 254 37.706 32.490 92.862 1.00134.54 C +ATOM 24740 NE ARG M 254 38.483 32.832 94.049 1.00140.85 N +ATOM 24741 CZ ARG M 254 39.749 32.477 94.241 1.00144.84 C +ATOM 24742 NH1 ARG M 254 40.387 31.766 93.322 1.00 99.11 N +ATOM 24743 NH2 ARG M 254 40.378 32.832 95.353 1.00192.17 N +ATOM 24744 N HIS M 255 37.636 37.410 90.603 1.00172.85 N +ATOM 24745 CA HIS M 255 36.802 38.593 90.848 1.00183.58 C +ATOM 24746 C HIS M 255 36.169 39.133 89.574 1.00170.46 C +ATOM 24747 O HIS M 255 35.035 39.618 89.599 1.00209.80 O +ATOM 24748 CB HIS M 255 37.602 39.704 91.542 1.00185.87 C +ATOM 24749 CG HIS M 255 37.247 39.887 92.987 1.00224.00 C +ATOM 24750 ND1 HIS M 255 37.649 39.004 93.968 1.00241.51 N +ATOM 24751 CD2 HIS M 255 36.495 40.826 93.611 1.00217.98 C +ATOM 24752 CE1 HIS M 255 37.176 39.404 95.137 1.00230.59 C +ATOM 24753 NE2 HIS M 255 36.469 40.504 94.947 1.00210.47 N +ATOM 24754 N MET M 256 36.875 39.013 88.457 1.00150.81 N +ATOM 24755 CA MET M 256 36.317 39.461 87.184 1.00161.29 C +ATOM 24756 C MET M 256 35.125 38.588 86.730 1.00133.30 C +ATOM 24757 O MET M 256 34.243 39.069 86.001 1.00112.11 O +ATOM 24758 CB MET M 256 37.409 39.522 86.104 1.00191.31 C +ATOM 24759 CG MET M 256 38.633 40.337 86.513 1.00185.71 C +ATOM 24760 SD MET M 256 39.689 40.889 85.163 1.00180.63 S +ATOM 24761 CE MET M 256 38.611 42.094 84.371 1.00149.02 C +ATOM 24762 N SER M 257 35.070 37.346 87.216 1.00124.61 N +ATOM 24763 CA SER M 257 33.921 36.453 87.009 1.00128.13 C +ATOM 24764 C SER M 257 32.730 36.785 87.914 1.00129.99 C +ATOM 24765 O SER M 257 31.905 37.629 87.545 1.00156.17 O +ATOM 24766 CB SER M 257 34.329 35.004 87.257 1.00132.45 C +ATOM 24767 OG SER M 257 35.615 34.734 86.709 1.00129.63 O +TER 24768 SER M 257 +ATOM 24769 N LEU N 2 61.604 55.583 71.629 1.00104.15 N +ATOM 24770 CA LEU N 2 60.161 55.686 71.222 1.00120.35 C +ATOM 24771 C LEU N 2 60.011 55.579 69.685 1.00129.43 C +ATOM 24772 O LEU N 2 59.702 56.563 68.978 1.00100.17 O +ATOM 24773 CB LEU N 2 59.525 56.975 71.767 1.00138.46 C +ATOM 24774 CG LEU N 2 59.452 57.194 73.299 1.00123.42 C +ATOM 24775 CD1 LEU N 2 58.811 58.549 73.588 1.00114.75 C +ATOM 24776 CD2 LEU N 2 58.717 56.085 74.062 1.00112.31 C +ATOM 24777 N THR N 3 60.406 54.404 69.192 1.00159.39 N +ATOM 24778 CA THR N 3 60.093 53.913 67.847 1.00143.60 C +ATOM 24779 C THR N 3 59.776 52.403 67.885 1.00152.24 C +ATOM 24780 O THR N 3 59.470 51.786 66.853 1.00181.78 O +ATOM 24781 CB THR N 3 61.259 54.142 66.848 1.00115.98 C +ATOM 24782 OG1 THR N 3 62.374 53.292 67.183 1.00 67.39 O +ATOM 24783 CG2 THR N 3 61.668 55.624 66.813 1.00100.55 C +ATOM 24784 N ALA N 4 59.933 51.797 69.060 1.00145.08 N +ATOM 24785 CA ALA N 4 59.305 50.510 69.350 1.00128.92 C +ATOM 24786 C ALA N 4 57.799 50.764 69.563 1.00127.76 C +ATOM 24787 O ALA N 4 57.325 51.890 69.368 1.00129.58 O +ATOM 24788 CB ALA N 4 59.959 49.845 70.563 1.00109.47 C +ATOM 24789 N PRO N 5 57.014 49.715 69.865 1.00136.48 N +ATOM 24790 CA PRO N 5 55.595 49.994 69.717 1.00127.73 C +ATOM 24791 C PRO N 5 55.009 50.803 70.895 1.00121.43 C +ATOM 24792 O PRO N 5 55.667 50.988 71.912 1.00147.37 O +ATOM 24793 CB PRO N 5 54.979 48.594 69.629 1.00128.08 C +ATOM 24794 CG PRO N 5 55.908 47.709 70.394 1.00159.62 C +ATOM 24795 CD PRO N 5 57.258 48.387 70.465 1.00164.94 C +ATOM 24796 N PRO N 6 53.782 51.314 70.739 1.00125.21 N +ATOM 24797 CA PRO N 6 53.005 51.844 71.859 1.00119.20 C +ATOM 24798 C PRO N 6 52.398 50.746 72.709 1.00112.02 C +ATOM 24799 O PRO N 6 52.087 49.661 72.206 1.00 98.46 O +ATOM 24800 CB PRO N 6 51.917 52.688 71.187 1.00139.69 C +ATOM 24801 CG PRO N 6 51.869 52.258 69.763 1.00130.52 C +ATOM 24802 CD PRO N 6 53.133 51.525 69.432 1.00140.87 C +ATOM 24803 N LYS N 7 52.206 51.026 73.997 1.00111.50 N +ATOM 24804 CA LYS N 7 51.820 49.983 74.933 1.00110.50 C +ATOM 24805 C LYS N 7 50.319 49.923 75.022 1.00104.74 C +ATOM 24806 O LYS N 7 49.557 50.652 74.341 1.00 89.31 O +ATOM 24807 CB LYS N 7 52.378 50.230 76.367 1.00123.83 C +ATOM 24808 CG LYS N 7 53.478 51.308 76.374 1.00124.69 C +ATOM 24809 CD LYS N 7 54.808 50.693 75.974 1.00119.93 C +ATOM 24810 CE LYS N 7 55.826 51.768 75.637 1.00106.64 C +ATOM 24811 NZ LYS N 7 57.218 51.330 75.919 1.00102.82 N +ATOM 24812 N GLU N 8 49.935 49.063 75.942 1.00100.75 N +ATOM 24813 CA GLU N 8 48.553 48.706 76.134 1.00 97.04 C +ATOM 24814 C GLU N 8 47.714 49.886 76.559 1.00 82.36 C +ATOM 24815 O GLU N 8 47.908 50.437 77.642 1.00 77.81 O +ATOM 24816 CB GLU N 8 48.421 47.634 77.201 1.00120.09 C +ATOM 24817 CG GLU N 8 47.723 46.355 76.855 1.00145.13 C +ATOM 24818 CD GLU N 8 47.622 45.424 78.067 1.00155.26 C +ATOM 24819 OE1 GLU N 8 48.643 45.114 78.716 1.00133.88 O +ATOM 24820 OE2 GLU N 8 46.560 44.870 78.312 1.00168.02 O +ATOM 24821 N ALA N 9 46.743 50.216 75.727 1.00 86.51 N +ATOM 24822 CA ALA N 9 45.673 51.105 76.097 1.00100.15 C +ATOM 24823 C ALA N 9 44.423 50.291 76.513 1.00112.57 C +ATOM 24824 O ALA N 9 43.760 49.667 75.664 1.00101.31 O +ATOM 24825 CB ALA N 9 45.353 52.014 74.927 1.00104.99 C +ATOM 24826 N ALA N 10 44.092 50.350 77.808 1.00 89.03 N +ATOM 24827 CA ALA N 10 43.006 49.561 78.423 1.00 86.22 C +ATOM 24828 C ALA N 10 43.484 48.161 78.780 1.00 88.46 C +ATOM 24829 O ALA N 10 44.492 47.706 78.277 1.00 71.68 O +ATOM 24830 CB ALA N 10 41.756 49.498 77.528 1.00 80.64 C +ATOM 24831 N ARG N 11 42.731 47.479 79.633 1.00111.67 N +ATOM 24832 CA ARG N 11 43.048 46.104 80.029 1.00136.56 C +ATOM 24833 C ARG N 11 42.160 45.131 79.256 1.00116.34 C +ATOM 24834 O ARG N 11 41.033 45.468 78.950 1.00 99.17 O +ATOM 24835 CB ARG N 11 42.838 45.904 81.550 1.00176.72 C +ATOM 24836 CG ARG N 11 41.395 46.027 82.018 1.00183.97 C +ATOM 24837 CD ARG N 11 41.322 46.489 83.473 1.00192.34 C +ATOM 24838 NE ARG N 11 40.878 47.877 83.591 1.00207.04 N +ATOM 24839 CZ ARG N 11 40.703 48.504 84.752 1.00208.14 C +ATOM 24840 NH1 ARG N 11 40.862 47.848 85.896 1.00226.41 N +ATOM 24841 NH2 ARG N 11 40.337 49.778 84.773 1.00191.73 N +ATOM 24842 N PRO N 12 42.640 43.894 79.008 1.00 96.48 N +ATOM 24843 CA PRO N 12 41.702 42.855 78.633 1.00 76.52 C +ATOM 24844 C PRO N 12 40.694 42.571 79.750 1.00 68.31 C +ATOM 24845 O PRO N 12 41.052 42.096 80.814 1.00 61.76 O +ATOM 24846 CB PRO N 12 42.602 41.629 78.371 1.00 74.99 C +ATOM 24847 CG PRO N 12 44.002 42.137 78.346 1.00 79.21 C +ATOM 24848 CD PRO N 12 43.986 43.343 79.232 1.00105.37 C +ATOM 24849 N THR N 13 39.438 42.895 79.501 1.00 81.72 N +ATOM 24850 CA THR N 13 38.338 42.424 80.324 1.00105.82 C +ATOM 24851 C THR N 13 37.712 41.158 79.730 1.00104.10 C +ATOM 24852 O THR N 13 37.864 40.904 78.529 1.00133.87 O +ATOM 24853 CB THR N 13 37.265 43.519 80.409 1.00140.16 C +ATOM 24854 OG1 THR N 13 36.298 43.162 81.402 1.00245.30 O +ATOM 24855 CG2 THR N 13 36.567 43.778 79.027 1.00107.22 C +ATOM 24856 N LEU N 14 36.970 40.385 80.516 1.00 79.96 N +ATOM 24857 CA LEU N 14 36.133 39.372 79.873 1.00 81.60 C +ATOM 24858 C LEU N 14 34.946 40.049 79.163 1.00 83.34 C +ATOM 24859 O LEU N 14 34.633 41.181 79.455 1.00 77.12 O +ATOM 24860 CB LEU N 14 35.719 38.247 80.818 1.00 80.64 C +ATOM 24861 CG LEU N 14 35.044 38.611 82.114 1.00103.69 C +ATOM 24862 CD1 LEU N 14 34.039 37.537 82.519 1.00115.30 C +ATOM 24863 CD2 LEU N 14 36.106 38.764 83.178 1.00117.59 C +ATOM 24864 N MET N 15 34.316 39.387 78.193 1.00101.70 N +ATOM 24865 CA MET N 15 33.545 40.112 77.166 1.00 98.64 C +ATOM 24866 C MET N 15 32.275 40.745 77.761 1.00100.63 C +ATOM 24867 O MET N 15 31.438 40.039 78.337 1.00133.21 O +ATOM 24868 CB MET N 15 33.184 39.201 75.966 1.00111.63 C +ATOM 24869 CG MET N 15 33.057 39.960 74.644 1.00118.41 C +ATOM 24870 SD MET N 15 31.879 39.427 73.374 1.00140.29 S +ATOM 24871 CE MET N 15 30.613 38.495 74.255 1.00109.84 C +ATOM 24872 N PRO N 16 32.115 42.068 77.592 1.00 79.51 N +ATOM 24873 CA PRO N 16 31.084 42.865 78.246 1.00 75.86 C +ATOM 24874 C PRO N 16 29.667 42.515 77.803 1.00 79.85 C +ATOM 24875 O PRO N 16 29.071 43.207 76.972 1.00105.69 O +ATOM 24876 CB PRO N 16 31.451 44.298 77.852 1.00 81.53 C +ATOM 24877 CG PRO N 16 32.238 44.145 76.601 1.00 88.44 C +ATOM 24878 CD PRO N 16 33.016 42.894 76.782 1.00 83.20 C +ATOM 24879 N ARG N 17 29.098 41.486 78.415 1.00 87.77 N +ATOM 24880 CA ARG N 17 27.689 41.144 78.200 1.00122.12 C +ATOM 24881 C ARG N 17 26.829 41.898 79.212 1.00150.13 C +ATOM 24882 O ARG N 17 27.274 42.140 80.331 1.00188.30 O +ATOM 24883 CB ARG N 17 27.493 39.639 78.358 1.00132.68 C +ATOM 24884 CG ARG N 17 27.726 38.865 77.078 1.00145.01 C +ATOM 24885 CD ARG N 17 27.955 37.379 77.319 1.00152.63 C +ATOM 24886 NE ARG N 17 29.308 37.101 77.801 1.00167.87 N +ATOM 24887 CZ ARG N 17 29.728 35.903 78.198 1.00174.74 C +ATOM 24888 NH1 ARG N 17 28.877 34.880 78.202 1.00168.56 N +ATOM 24889 NH2 ARG N 17 30.993 35.729 78.588 1.00160.44 N +ATOM 24890 N ALA N 18 25.611 42.285 78.830 1.00148.62 N +ATOM 24891 CA ALA N 18 24.752 43.087 79.718 1.00127.81 C +ATOM 24892 C ALA N 18 23.495 42.332 80.184 1.00139.53 C +ATOM 24893 O ALA N 18 23.607 41.321 80.892 1.00135.75 O +ATOM 24894 CB ALA N 18 24.384 44.413 79.068 1.00122.19 C +ATOM 24895 N GLN N 19 22.312 42.847 79.847 1.00133.27 N +ATOM 24896 CA GLN N 19 21.096 42.498 80.586 1.00158.47 C +ATOM 24897 C GLN N 19 20.665 41.067 80.295 1.00146.90 C +ATOM 24898 O GLN N 19 20.366 40.275 81.214 1.00121.12 O +ATOM 24899 CB GLN N 19 19.961 43.466 80.231 1.00178.19 C +ATOM 24900 CG GLN N 19 18.686 43.268 81.044 1.00199.00 C +ATOM 24901 CD GLN N 19 18.929 43.316 82.548 1.00172.94 C +ATOM 24902 OE1 GLN N 19 19.285 44.358 83.096 1.00156.77 O +ATOM 24903 NE2 GLN N 19 18.747 42.180 83.216 1.00147.15 N +ATOM 24904 N SER N 20 20.585 40.769 79.004 1.00122.13 N +ATOM 24905 CA SER N 20 20.321 39.426 78.535 1.00142.31 C +ATOM 24906 C SER N 20 21.114 38.388 79.351 1.00165.51 C +ATOM 24907 O SER N 20 20.552 37.393 79.826 1.00141.96 O +ATOM 24908 CB SER N 20 20.688 39.342 77.049 1.00139.59 C +ATOM 24909 OG SER N 20 20.080 40.396 76.320 1.00123.39 O +ATOM 24910 N TYR N 21 22.420 38.622 79.485 1.00173.24 N +ATOM 24911 CA TYR N 21 23.304 37.747 80.256 1.00166.24 C +ATOM 24912 C TYR N 21 22.836 37.575 81.699 1.00150.45 C +ATOM 24913 O TYR N 21 22.761 36.446 82.213 1.00151.53 O +ATOM 24914 CB TYR N 21 24.732 38.297 80.247 1.00165.50 C +ATOM 24915 CG TYR N 21 25.718 37.422 80.998 1.00163.02 C +ATOM 24916 CD1 TYR N 21 26.196 36.236 80.434 1.00144.51 C +ATOM 24917 CD2 TYR N 21 26.158 37.772 82.274 1.00146.26 C +ATOM 24918 CE1 TYR N 21 27.085 35.438 81.109 1.00126.04 C +ATOM 24919 CE2 TYR N 21 27.063 36.981 82.959 1.00131.22 C +ATOM 24920 CZ TYR N 21 27.523 35.821 82.369 1.00132.69 C +ATOM 24921 OH TYR N 21 28.427 35.018 83.019 1.00146.95 O +ATOM 24922 N LYS N 22 22.548 38.695 82.354 1.00124.81 N +ATOM 24923 CA LYS N 22 22.152 38.679 83.757 1.00132.91 C +ATOM 24924 C LYS N 22 20.881 37.868 83.975 1.00133.55 C +ATOM 24925 O LYS N 22 20.758 37.138 84.967 1.00132.62 O +ATOM 24926 CB LYS N 22 21.952 40.106 84.262 1.00144.46 C +ATOM 24927 CG LYS N 22 23.217 40.738 84.812 1.00157.28 C +ATOM 24928 CD LYS N 22 23.449 40.291 86.261 1.00171.14 C +ATOM 24929 CE LYS N 22 23.033 41.404 87.229 1.00179.39 C +ATOM 24930 NZ LYS N 22 23.899 42.604 87.083 1.00181.50 N +ATOM 24931 N ASP N 23 19.933 38.017 83.056 1.00140.38 N +ATOM 24932 CA ASP N 23 18.707 37.218 83.076 1.00148.61 C +ATOM 24933 C ASP N 23 19.024 35.745 82.858 1.00136.23 C +ATOM 24934 O ASP N 23 18.495 34.872 83.559 1.00162.81 O +ATOM 24935 CB ASP N 23 17.742 37.696 81.988 1.00140.81 C +ATOM 24936 CG ASP N 23 17.197 39.066 82.265 1.00162.01 C +ATOM 24937 OD1 ASP N 23 16.861 39.335 83.438 1.00187.58 O +ATOM 24938 OD2 ASP N 23 17.088 39.873 81.313 1.00186.91 O +ATOM 24939 N LEU N 24 19.882 35.486 81.877 1.00118.32 N +ATOM 24940 CA LEU N 24 20.194 34.127 81.446 1.00139.10 C +ATOM 24941 C LEU N 24 20.888 33.318 82.548 1.00153.23 C +ATOM 24942 O LEU N 24 20.670 32.094 82.678 1.00140.41 O +ATOM 24943 CB LEU N 24 21.080 34.177 80.194 1.00134.16 C +ATOM 24944 CG LEU N 24 21.520 32.846 79.566 1.00132.84 C +ATOM 24945 CD1 LEU N 24 20.472 32.315 78.595 1.00122.10 C +ATOM 24946 CD2 LEU N 24 22.855 33.022 78.860 1.00142.35 C +ATOM 24947 N THR N 25 21.728 33.999 83.330 1.00164.97 N +ATOM 24948 CA THR N 25 22.511 33.341 84.389 1.00169.04 C +ATOM 24949 C THR N 25 21.664 33.022 85.620 1.00177.41 C +ATOM 24950 O THR N 25 21.689 31.892 86.128 1.00170.73 O +ATOM 24951 CB THR N 25 23.709 34.205 84.826 1.00140.68 C +ATOM 24952 OG1 THR N 25 23.284 35.557 85.010 1.00142.84 O +ATOM 24953 CG2 THR N 25 24.793 34.164 83.770 1.00146.23 C +ATOM 24954 N HIS N 26 20.868 33.999 86.048 1.00186.39 N +ATOM 24955 CA HIS N 26 20.018 33.861 87.234 1.00187.59 C +ATOM 24956 C HIS N 26 18.674 33.176 86.911 1.00156.91 C +ATOM 24957 O HIS N 26 17.633 33.514 87.467 1.00125.49 O +ATOM 24958 CB HIS N 26 19.799 35.241 87.880 1.00201.29 C +ATOM 24959 CG HIS N 26 21.064 35.875 88.391 1.00200.13 C +ATOM 24960 ND1 HIS N 26 22.059 36.338 87.554 1.00198.46 N +ATOM 24961 CD2 HIS N 26 21.503 36.104 89.652 1.00192.49 C +ATOM 24962 CE1 HIS N 26 23.048 36.835 88.276 1.00186.08 C +ATOM 24963 NE2 HIS N 26 22.738 36.701 89.553 1.00187.53 N +ATOM 24964 N LEU N 27 18.698 32.209 86.004 1.00131.93 N +ATOM 24965 CA LEU N 27 17.508 31.426 85.708 1.00120.61 C +ATOM 24966 C LEU N 27 17.441 30.248 86.678 1.00115.58 C +ATOM 24967 O LEU N 27 18.432 29.543 86.863 1.00134.92 O +ATOM 24968 CB LEU N 27 17.524 30.935 84.245 1.00122.52 C +ATOM 24969 CG LEU N 27 16.919 31.900 83.222 1.00138.80 C +ATOM 24970 CD1 LEU N 27 17.266 31.481 81.804 1.00156.42 C +ATOM 24971 CD2 LEU N 27 15.409 31.998 83.385 1.00144.90 C +ATOM 24972 N PRO N 28 16.253 29.980 87.235 1.00107.63 N +ATOM 24973 CA PRO N 28 16.058 28.817 88.103 1.00105.84 C +ATOM 24974 C PRO N 28 16.420 27.497 87.432 1.00100.90 C +ATOM 24975 O PRO N 28 15.927 27.208 86.349 1.00127.95 O +ATOM 24976 CB PRO N 28 14.553 28.853 88.403 1.00134.23 C +ATOM 24977 CG PRO N 28 13.942 29.589 87.249 1.00129.37 C +ATOM 24978 CD PRO N 28 14.973 30.603 86.845 1.00122.19 C +ATOM 24979 N ALA N 29 17.237 26.684 88.088 1.00106.78 N +ATOM 24980 CA ALA N 29 17.828 25.505 87.442 1.00106.56 C +ATOM 24981 C ALA N 29 16.800 24.368 87.217 1.00111.69 C +ATOM 24982 O ALA N 29 15.854 24.203 87.997 1.00135.93 O +ATOM 24983 CB ALA N 29 19.039 25.013 88.240 1.00 95.02 C +ATOM 24984 N PRO N 30 16.954 23.609 86.119 1.00103.21 N +ATOM 24985 CA PRO N 30 16.142 22.419 85.837 1.00104.66 C +ATOM 24986 C PRO N 30 16.521 21.210 86.704 1.00 97.02 C +ATOM 24987 O PRO N 30 17.505 21.274 87.456 1.00 64.92 O +ATOM 24988 CB PRO N 30 16.483 22.111 84.392 1.00108.75 C +ATOM 24989 CG PRO N 30 17.888 22.579 84.241 1.00130.83 C +ATOM 24990 CD PRO N 30 18.055 23.759 85.156 1.00118.77 C +ATOM 24991 N THR N 31 15.765 20.116 86.573 1.00 97.75 N +ATOM 24992 CA THR N 31 16.017 18.907 87.374 1.00132.34 C +ATOM 24993 C THR N 31 17.340 18.218 87.012 1.00133.66 C +ATOM 24994 O THR N 31 17.946 17.537 87.838 1.00106.64 O +ATOM 24995 CB THR N 31 14.866 17.867 87.274 1.00143.09 C +ATOM 24996 OG1 THR N 31 14.574 17.565 85.907 1.00122.23 O +ATOM 24997 CG2 THR N 31 13.607 18.380 87.958 1.00152.29 C +ATOM 24998 N GLY N 32 17.765 18.380 85.767 1.00147.39 N +ATOM 24999 CA GLY N 32 19.116 18.009 85.352 1.00157.62 C +ATOM 25000 C GLY N 32 19.483 18.818 84.123 1.00153.21 C +ATOM 25001 O GLY N 32 18.594 19.297 83.421 1.00168.27 O +ATOM 25002 N LYS N 33 20.775 19.035 83.885 1.00122.53 N +ATOM 25003 CA LYS N 33 21.173 19.754 82.690 1.00103.08 C +ATOM 25004 C LYS N 33 20.865 18.914 81.445 1.00110.71 C +ATOM 25005 O LYS N 33 20.866 17.682 81.505 1.00107.70 O +ATOM 25006 CB LYS N 33 22.643 20.145 82.741 1.00109.43 C +ATOM 25007 CG LYS N 33 22.868 21.519 83.364 1.00102.11 C +ATOM 25008 CD LYS N 33 24.320 21.806 83.388 1.00107.44 C +ATOM 25009 CE LYS N 33 24.925 21.154 84.581 1.00113.05 C +ATOM 25010 NZ LYS N 33 26.284 20.667 84.273 1.00130.26 N +ATOM 25011 N ILE N 34 20.597 19.578 80.323 1.00113.23 N +ATOM 25012 CA ILE N 34 20.235 18.882 79.098 1.00121.86 C +ATOM 25013 C ILE N 34 21.437 18.926 78.135 1.00137.99 C +ATOM 25014 O ILE N 34 22.209 19.895 78.131 1.00128.57 O +ATOM 25015 CB ILE N 34 18.924 19.468 78.503 1.00132.93 C +ATOM 25016 CG1 ILE N 34 17.746 19.186 79.440 1.00133.85 C +ATOM 25017 CG2 ILE N 34 18.586 18.861 77.145 1.00156.50 C +ATOM 25018 CD1 ILE N 34 17.094 20.438 79.977 1.00144.43 C +ATOM 25019 N PHE N 35 21.644 17.820 77.416 1.00129.68 N +ATOM 25020 CA PHE N 35 22.732 17.679 76.455 1.00105.03 C +ATOM 25021 C PHE N 35 22.337 18.304 75.133 1.00109.54 C +ATOM 25022 O PHE N 35 21.344 17.890 74.528 1.00133.65 O +ATOM 25023 CB PHE N 35 22.996 16.198 76.204 1.00110.20 C +ATOM 25024 CG PHE N 35 23.930 15.566 77.186 1.00 99.67 C +ATOM 25025 CD1 PHE N 35 25.085 16.217 77.590 1.00 75.47 C +ATOM 25026 CD2 PHE N 35 23.690 14.265 77.629 1.00 92.78 C +ATOM 25027 CE1 PHE N 35 25.954 15.602 78.463 1.00 93.16 C +ATOM 25028 CE2 PHE N 35 24.565 13.643 78.492 1.00 92.03 C +ATOM 25029 CZ PHE N 35 25.696 14.314 78.918 1.00100.40 C +ATOM 25030 N VAL N 36 23.152 19.230 74.631 1.00102.05 N +ATOM 25031 CA VAL N 36 22.800 19.929 73.400 1.00 84.44 C +ATOM 25032 C VAL N 36 23.933 19.989 72.388 1.00102.53 C +ATOM 25033 O VAL N 36 25.113 19.944 72.737 1.00142.24 O +ATOM 25034 CB VAL N 36 22.365 21.342 73.715 1.00 79.45 C +ATOM 25035 CG1 VAL N 36 23.566 22.221 74.053 1.00 81.13 C +ATOM 25036 CG2 VAL N 36 21.597 21.905 72.549 1.00 90.61 C +ATOM 25037 N SER N 37 23.569 20.035 71.120 1.00 93.50 N +ATOM 25038 CA SER N 37 24.554 20.082 70.059 1.00104.18 C +ATOM 25039 C SER N 37 24.296 21.354 69.274 1.00 92.71 C +ATOM 25040 O SER N 37 23.196 21.576 68.814 1.00 68.49 O +ATOM 25041 CB SER N 37 24.405 18.862 69.133 1.00 94.98 C +ATOM 25042 OG SER N 37 24.911 17.688 69.718 1.00 65.63 O +ATOM 25043 N VAL N 38 25.345 22.104 68.980 1.00 93.67 N +ATOM 25044 CA VAL N 38 25.247 23.121 67.930 1.00 88.14 C +ATOM 25045 C VAL N 38 26.285 22.874 66.821 1.00 95.29 C +ATOM 25046 O VAL N 38 27.491 22.875 67.092 1.00121.84 O +ATOM 25047 CB VAL N 38 25.497 24.522 68.491 1.00 71.68 C +ATOM 25048 CG1 VAL N 38 25.428 25.547 67.380 1.00 60.13 C +ATOM 25049 CG2 VAL N 38 24.515 24.848 69.596 1.00 71.75 C +ATOM 25050 N TYR N 39 25.804 22.684 65.594 1.00 84.58 N +ATOM 25051 CA TYR N 39 26.656 22.401 64.455 1.00 83.05 C +ATOM 25052 C TYR N 39 27.050 23.721 63.796 1.00 90.70 C +ATOM 25053 O TYR N 39 28.230 23.989 63.582 1.00112.31 O +ATOM 25054 CB TYR N 39 25.949 21.440 63.470 1.00 87.24 C +ATOM 25055 CG TYR N 39 26.132 19.974 63.839 1.00 98.16 C +ATOM 25056 CD1 TYR N 39 25.410 19.386 64.872 1.00 71.76 C +ATOM 25057 CD2 TYR N 39 27.065 19.178 63.158 1.00148.77 C +ATOM 25058 CE1 TYR N 39 25.594 18.059 65.196 1.00 83.16 C +ATOM 25059 CE2 TYR N 39 27.266 17.835 63.479 1.00155.36 C +ATOM 25060 CZ TYR N 39 26.537 17.280 64.512 1.00120.61 C +ATOM 25061 OH TYR N 39 26.771 15.942 64.838 1.00100.96 O +ATOM 25062 N ASN N 40 26.069 24.546 63.447 1.00 99.70 N +ATOM 25063 CA ASN N 40 26.358 25.811 62.762 1.00 98.15 C +ATOM 25064 C ASN N 40 25.190 26.793 62.684 1.00 93.92 C +ATOM 25065 O ASN N 40 24.061 26.412 62.351 1.00 78.29 O +ATOM 25066 CB ASN N 40 26.813 25.543 61.338 1.00105.99 C +ATOM 25067 CG ASN N 40 27.544 26.724 60.745 1.00134.54 C +ATOM 25068 OD1 ASN N 40 27.101 27.316 59.764 1.00139.14 O +ATOM 25069 ND2 ASN N 40 28.681 27.075 61.343 1.00163.28 N +ATOM 25070 N ILE N 41 25.455 28.053 63.024 1.00 95.76 N +ATOM 25071 CA ILE N 41 24.483 29.126 62.816 1.00 97.91 C +ATOM 25072 C ILE N 41 25.072 30.120 61.821 1.00114.61 C +ATOM 25073 O ILE N 41 26.095 30.750 62.102 1.00119.65 O +ATOM 25074 CB ILE N 41 24.116 29.855 64.129 1.00 77.63 C +ATOM 25075 CG1 ILE N 41 23.067 29.074 64.921 1.00 89.33 C +ATOM 25076 CG2 ILE N 41 23.488 31.199 63.818 1.00 75.58 C +ATOM 25077 CD1 ILE N 41 23.554 27.792 65.558 1.00102.08 C +ATOM 25078 N GLN N 42 24.431 30.264 60.660 1.00116.46 N +ATOM 25079 CA GLN N 42 25.034 31.005 59.540 1.00105.01 C +ATOM 25080 C GLN N 42 24.698 32.489 59.560 1.00 74.72 C +ATOM 25081 O GLN N 42 23.682 32.878 60.100 1.00 58.88 O +ATOM 25082 CB GLN N 42 24.594 30.431 58.194 1.00113.35 C +ATOM 25083 CG GLN N 42 25.029 29.013 57.925 1.00129.10 C +ATOM 25084 CD GLN N 42 23.798 28.116 57.749 1.00147.48 C +ATOM 25085 OE1 GLN N 42 23.394 27.848 56.631 1.00144.98 O +ATOM 25086 NE2 GLN N 42 23.286 27.561 58.857 1.00141.56 N +ATOM 25087 N ASP N 43 25.571 33.285 58.944 1.00 60.82 N +ATOM 25088 CA ASP N 43 25.287 34.651 58.624 1.00 56.35 C +ATOM 25089 C ASP N 43 24.396 34.704 57.393 1.00 70.29 C +ATOM 25090 O ASP N 43 24.790 35.268 56.352 1.00 67.30 O +ATOM 25091 CB ASP N 43 26.569 35.411 58.341 1.00 60.61 C +ATOM 25092 CG ASP N 43 26.339 36.933 58.230 1.00 84.22 C +ATOM 25093 OD1 ASP N 43 25.714 37.510 59.156 1.00121.66 O +ATOM 25094 OD2 ASP N 43 26.864 37.591 57.298 1.00 68.62 O +ATOM 25095 N GLU N 44 23.157 34.199 57.525 1.00 83.10 N +ATOM 25096 CA GLU N 44 22.157 34.228 56.430 1.00100.33 C +ATOM 25097 C GLU N 44 21.637 35.679 56.069 1.00 85.74 C +ATOM 25098 O GLU N 44 20.670 35.830 55.284 1.00 45.68 O +ATOM 25099 CB GLU N 44 20.956 33.301 56.755 1.00101.71 C +ATOM 25100 CG GLU N 44 21.138 31.824 56.383 1.00100.69 C +ATOM 25101 CD GLU N 44 19.939 30.906 56.734 1.00 96.65 C +ATOM 25102 OE1 GLU N 44 18.760 31.282 56.526 1.00135.57 O +ATOM 25103 OE2 GLU N 44 20.166 29.814 57.287 1.00 74.93 O +ATOM 25104 N THR N 45 22.375 36.702 56.532 1.00 79.07 N +ATOM 25105 CA THR N 45 21.966 38.096 56.418 1.00 83.14 C +ATOM 25106 C THR N 45 22.128 38.696 55.027 1.00 87.68 C +ATOM 25107 O THR N 45 21.230 39.377 54.543 1.00 88.44 O +ATOM 25108 CB THR N 45 22.658 39.001 57.466 1.00 71.90 C +ATOM 25109 OG1 THR N 45 21.950 40.239 57.520 1.00146.77 O +ATOM 25110 CG2 THR N 45 24.108 39.274 57.158 1.00 50.73 C +ATOM 25111 N GLY N 46 23.232 38.384 54.358 1.00107.94 N +ATOM 25112 CA GLY N 46 23.404 38.728 52.934 1.00103.89 C +ATOM 25113 C GLY N 46 24.023 40.109 52.782 1.00117.69 C +ATOM 25114 O GLY N 46 23.952 40.763 51.723 1.00142.93 O +ATOM 25115 N GLN N 47 24.638 40.580 53.842 1.00 90.41 N +ATOM 25116 CA GLN N 47 24.912 41.956 53.885 1.00 67.40 C +ATOM 25117 C GLN N 47 26.358 42.227 54.208 1.00 77.60 C +ATOM 25118 O GLN N 47 27.007 41.580 55.057 1.00 91.59 O +ATOM 25119 CB GLN N 47 23.999 42.567 54.873 1.00 59.18 C +ATOM 25120 CG GLN N 47 22.567 42.552 54.410 1.00 78.47 C +ATOM 25121 CD GLN N 47 22.387 43.114 53.016 1.00116.40 C +ATOM 25122 OE1 GLN N 47 22.493 44.308 52.793 1.00124.42 O +ATOM 25123 NE2 GLN N 47 22.085 42.251 52.068 1.00184.10 N +ATOM 25124 N PHE N 48 26.881 43.214 53.499 1.00 83.71 N +ATOM 25125 CA PHE N 48 28.245 43.686 53.696 1.00 79.88 C +ATOM 25126 C PHE N 48 28.243 45.181 54.016 1.00 82.18 C +ATOM 25127 O PHE N 48 27.269 45.904 53.777 1.00 82.52 O +ATOM 25128 CB PHE N 48 29.087 43.400 52.441 1.00 71.85 C +ATOM 25129 CG PHE N 48 29.283 41.961 52.206 1.00 57.01 C +ATOM 25130 CD1 PHE N 48 28.233 41.195 51.781 1.00 53.62 C +ATOM 25131 CD2 PHE N 48 30.458 41.375 52.505 1.00 66.83 C +ATOM 25132 CE1 PHE N 48 28.345 39.848 51.642 1.00 61.57 C +ATOM 25133 CE2 PHE N 48 30.591 40.023 52.373 1.00 97.21 C +ATOM 25134 CZ PHE N 48 29.537 39.259 51.912 1.00 89.15 C +ATOM 25135 N LYS N 49 29.399 45.650 54.446 1.00 92.20 N +ATOM 25136 CA LYS N 49 29.556 47.048 54.774 1.00 97.09 C +ATOM 25137 C LYS N 49 29.674 47.884 53.506 1.00 94.24 C +ATOM 25138 O LYS N 49 30.239 47.442 52.495 1.00 89.15 O +ATOM 25139 CB LYS N 49 30.773 47.240 55.690 1.00116.91 C +ATOM 25140 CG LYS N 49 30.579 46.557 57.039 1.00110.37 C +ATOM 25141 CD LYS N 49 31.618 46.846 58.107 1.00123.50 C +ATOM 25142 CE LYS N 49 31.112 46.202 59.403 1.00140.17 C +ATOM 25143 NZ LYS N 49 31.970 46.405 60.598 1.00156.07 N +ATOM 25144 N PRO N 50 29.151 49.111 53.568 1.00 95.79 N +ATOM 25145 CA PRO N 50 29.224 50.033 52.448 1.00113.77 C +ATOM 25146 C PRO N 50 30.589 50.720 52.319 1.00 97.57 C +ATOM 25147 O PRO N 50 31.408 50.668 53.240 1.00 85.73 O +ATOM 25148 CB PRO N 50 28.124 51.057 52.771 1.00117.89 C +ATOM 25149 CG PRO N 50 28.049 51.061 54.253 1.00103.58 C +ATOM 25150 CD PRO N 50 28.369 49.659 54.689 1.00 95.31 C +ATOM 25151 N TYR N 51 30.805 51.367 51.175 1.00 87.14 N +ATOM 25152 CA TYR N 51 31.952 52.222 51.010 1.00 73.51 C +ATOM 25153 C TYR N 51 32.055 53.164 52.203 1.00 70.69 C +ATOM 25154 O TYR N 51 31.054 53.738 52.634 1.00 65.33 O +ATOM 25155 CB TYR N 51 31.859 53.028 49.716 1.00 73.46 C +ATOM 25156 CG TYR N 51 33.185 53.639 49.353 1.00 68.35 C +ATOM 25157 CD1 TYR N 51 34.073 52.942 48.594 1.00 78.81 C +ATOM 25158 CD2 TYR N 51 33.534 54.926 49.757 1.00 81.83 C +ATOM 25159 CE1 TYR N 51 35.312 53.462 48.278 1.00103.03 C +ATOM 25160 CE2 TYR N 51 34.761 55.487 49.398 1.00 95.35 C +ATOM 25161 CZ TYR N 51 35.664 54.714 48.693 1.00105.78 C +ATOM 25162 OH TYR N 51 36.918 55.170 48.342 1.00115.06 O +ATOM 25163 N PRO N 52 33.265 53.338 52.750 1.00 83.38 N +ATOM 25164 CA PRO N 52 34.575 52.868 52.270 1.00110.43 C +ATOM 25165 C PRO N 52 35.084 51.532 52.798 1.00129.45 C +ATOM 25166 O PRO N 52 36.295 51.276 52.704 1.00117.21 O +ATOM 25167 CB PRO N 52 35.519 53.974 52.748 1.00117.30 C +ATOM 25168 CG PRO N 52 34.906 54.416 54.043 1.00113.81 C +ATOM 25169 CD PRO N 52 33.411 54.281 53.875 1.00 88.97 C +ATOM 25170 N ALA N 53 34.204 50.691 53.348 1.00122.93 N +ATOM 25171 CA ALA N 53 34.644 49.386 53.827 1.00117.04 C +ATOM 25172 C ALA N 53 35.117 48.553 52.657 1.00120.95 C +ATOM 25173 O ALA N 53 34.771 48.810 51.485 1.00 86.41 O +ATOM 25174 CB ALA N 53 33.536 48.658 54.565 1.00125.10 C +ATOM 25175 N SER N 54 35.921 47.543 52.961 1.00116.11 N +ATOM 25176 CA SER N 54 36.219 46.572 51.928 1.00 90.77 C +ATOM 25177 C SER N 54 34.900 45.990 51.421 1.00 72.48 C +ATOM 25178 O SER N 54 33.976 45.703 52.217 1.00 73.14 O +ATOM 25179 CB SER N 54 37.162 45.476 52.438 1.00 96.43 C +ATOM 25180 OG SER N 54 37.093 44.288 51.634 1.00 62.76 O +ATOM 25181 N ASN N 55 34.856 45.767 50.111 1.00 49.97 N +ATOM 25182 CA ASN N 55 33.797 45.017 49.484 1.00 48.63 C +ATOM 25183 C ASN N 55 33.407 43.721 50.239 1.00 65.21 C +ATOM 25184 O ASN N 55 32.239 43.295 50.292 1.00 47.19 O +ATOM 25185 CB ASN N 55 34.219 44.651 48.094 1.00 42.24 C +ATOM 25186 CG ASN N 55 33.069 44.254 47.250 1.00 73.99 C +ATOM 25187 OD1 ASN N 55 31.897 44.566 47.533 1.00161.77 O +ATOM 25188 ND2 ASN N 55 33.377 43.658 46.133 1.00100.59 N +ATOM 25189 N PHE N 56 34.394 43.133 50.907 1.00 93.12 N +ATOM 25190 CA PHE N 56 34.257 41.814 51.539 1.00 90.55 C +ATOM 25191 C PHE N 56 34.007 41.862 53.042 1.00 97.93 C +ATOM 25192 O PHE N 56 33.923 40.822 53.690 1.00105.83 O +ATOM 25193 CB PHE N 56 35.524 41.005 51.328 1.00 80.66 C +ATOM 25194 CG PHE N 56 35.883 40.836 49.872 1.00 72.69 C +ATOM 25195 CD1 PHE N 56 35.027 40.228 48.968 1.00 43.95 C +ATOM 25196 CD2 PHE N 56 37.055 41.366 49.412 1.00 90.72 C +ATOM 25197 CE1 PHE N 56 35.367 40.097 47.655 1.00 35.27 C +ATOM 25198 CE2 PHE N 56 37.422 41.183 48.092 1.00 72.33 C +ATOM 25199 CZ PHE N 56 36.559 40.569 47.209 1.00 43.24 C +ATOM 25200 N SER N 57 33.935 43.053 53.615 1.00 84.21 N +ATOM 25201 CA SER N 57 33.670 43.151 55.042 1.00 70.07 C +ATOM 25202 C SER N 57 32.193 42.860 55.310 1.00 64.99 C +ATOM 25203 O SER N 57 31.296 43.607 54.859 1.00 79.40 O +ATOM 25204 CB SER N 57 34.075 44.532 55.571 1.00 69.35 C +ATOM 25205 OG SER N 57 35.487 44.627 55.639 1.00 60.33 O +ATOM 25206 N THR N 58 31.924 41.777 56.023 1.00 46.48 N +ATOM 25207 CA THR N 58 30.552 41.432 56.315 1.00 57.19 C +ATOM 25208 C THR N 58 29.935 42.413 57.295 1.00 72.81 C +ATOM 25209 O THR N 58 30.584 42.940 58.166 1.00 77.05 O +ATOM 25210 CB THR N 58 30.451 40.030 56.918 1.00 44.99 C +ATOM 25211 OG1 THR N 58 31.153 39.995 58.151 1.00 35.76 O +ATOM 25212 CG2 THR N 58 31.058 39.069 55.982 1.00 39.48 C +ATOM 25213 N ALA N 59 28.629 42.578 57.237 1.00103.95 N +ATOM 25214 CA ALA N 59 27.997 43.505 58.166 1.00 97.82 C +ATOM 25215 C ALA N 59 27.875 42.914 59.566 1.00 83.34 C +ATOM 25216 O ALA N 59 27.747 43.641 60.540 1.00 95.28 O +ATOM 25217 CB ALA N 59 26.636 43.917 57.656 1.00116.75 C +ATOM 25218 N VAL N 60 27.935 41.588 59.658 1.00 93.45 N +ATOM 25219 CA VAL N 60 27.687 40.874 60.901 1.00 92.81 C +ATOM 25220 C VAL N 60 28.798 39.863 61.114 1.00 82.84 C +ATOM 25221 O VAL N 60 29.245 39.205 60.159 1.00 94.59 O +ATOM 25222 CB VAL N 60 26.345 40.129 60.807 1.00109.20 C +ATOM 25223 CG1 VAL N 60 26.054 39.337 62.082 1.00129.54 C +ATOM 25224 CG2 VAL N 60 25.221 41.109 60.514 1.00111.23 C +ATOM 25225 N PRO N 61 29.226 39.696 62.360 1.00 60.23 N +ATOM 25226 CA PRO N 61 30.293 38.732 62.581 1.00 77.40 C +ATOM 25227 C PRO N 61 29.862 37.300 62.316 1.00 84.57 C +ATOM 25228 O PRO N 61 28.712 36.937 62.592 1.00 53.24 O +ATOM 25229 CB PRO N 61 30.634 38.909 64.061 1.00 76.78 C +ATOM 25230 CG PRO N 61 29.433 39.553 64.648 1.00 61.83 C +ATOM 25231 CD PRO N 61 28.901 40.438 63.567 1.00 53.91 C +ATOM 25232 N GLN N 62 30.805 36.495 61.806 1.00105.27 N +ATOM 25233 CA GLN N 62 30.523 35.124 61.397 1.00 98.36 C +ATOM 25234 C GLN N 62 30.722 34.189 62.577 1.00 98.13 C +ATOM 25235 O GLN N 62 31.077 33.028 62.383 1.00156.11 O +ATOM 25236 CB GLN N 62 31.463 34.683 60.269 1.00 83.74 C +ATOM 25237 CG GLN N 62 31.560 35.658 59.125 1.00 72.95 C +ATOM 25238 CD GLN N 62 30.219 35.914 58.498 1.00 70.14 C +ATOM 25239 OE1 GLN N 62 29.694 35.077 57.737 1.00113.62 O +ATOM 25240 NE2 GLN N 62 29.646 37.070 58.786 1.00 53.88 N +ATOM 25241 N SER N 63 30.381 34.654 63.772 1.00 68.34 N +ATOM 25242 CA SER N 63 30.760 33.962 64.971 1.00 64.46 C +ATOM 25243 C SER N 63 29.568 33.483 65.818 1.00 72.96 C +ATOM 25244 O SER N 63 29.719 33.061 66.970 1.00 79.30 O +ATOM 25245 CB SER N 63 31.668 34.900 65.757 1.00 71.11 C +ATOM 25246 OG SER N 63 31.019 36.093 66.163 1.00 90.12 O +ATOM 25247 N ALA N 64 28.367 33.599 65.261 1.00 85.36 N +ATOM 25248 CA ALA N 64 27.128 33.350 65.997 1.00 89.64 C +ATOM 25249 C ALA N 64 27.099 31.964 66.684 1.00107.95 C +ATOM 25250 O ALA N 64 26.585 31.809 67.801 1.00 75.96 O +ATOM 25251 CB ALA N 64 25.950 33.501 65.054 1.00 88.72 C +ATOM 25252 N THR N 65 27.642 30.966 65.994 1.00128.21 N +ATOM 25253 CA THR N 65 27.648 29.591 66.472 1.00125.16 C +ATOM 25254 C THR N 65 28.255 29.508 67.858 1.00125.86 C +ATOM 25255 O THR N 65 27.688 28.884 68.763 1.00191.71 O +ATOM 25256 CB THR N 65 28.495 28.724 65.540 1.00118.16 C +ATOM 25257 OG1 THR N 65 28.235 29.124 64.192 1.00143.88 O +ATOM 25258 CG2 THR N 65 28.174 27.244 65.732 1.00106.39 C +ATOM 25259 N ALA N 66 29.413 30.127 68.021 1.00 96.43 N +ATOM 25260 CA ALA N 66 30.126 30.013 69.266 1.00 95.37 C +ATOM 25261 C ALA N 66 29.406 30.788 70.354 1.00 80.03 C +ATOM 25262 O ALA N 66 29.428 30.391 71.539 1.00 59.60 O +ATOM 25263 CB ALA N 66 31.553 30.501 69.083 1.00125.72 C +ATOM 25264 N MET N 67 28.778 31.901 69.952 1.00 74.49 N +ATOM 25265 CA MET N 67 28.026 32.748 70.898 1.00 87.69 C +ATOM 25266 C MET N 67 26.825 31.969 71.448 1.00 97.93 C +ATOM 25267 O MET N 67 26.543 31.983 72.660 1.00 80.25 O +ATOM 25268 CB MET N 67 27.533 34.032 70.241 1.00 66.73 C +ATOM 25269 CG MET N 67 28.610 35.057 69.909 1.00 57.94 C +ATOM 25270 SD MET N 67 27.926 36.351 68.833 1.00 96.37 S +ATOM 25271 CE MET N 67 29.295 37.506 68.770 1.00 79.70 C +ATOM 25272 N LEU N 68 26.187 31.205 70.566 1.00 98.50 N +ATOM 25273 CA LEU N 68 25.051 30.382 70.979 1.00 94.22 C +ATOM 25274 C LEU N 68 25.484 29.280 71.932 1.00 84.26 C +ATOM 25275 O LEU N 68 24.823 29.061 72.941 1.00 95.33 O +ATOM 25276 CB LEU N 68 24.340 29.751 69.781 1.00 74.85 C +ATOM 25277 CG LEU N 68 23.294 28.710 70.199 1.00 60.67 C +ATOM 25278 CD1 LEU N 68 22.135 29.373 70.923 1.00 75.37 C +ATOM 25279 CD2 LEU N 68 22.772 27.936 69.008 1.00 65.49 C +ATOM 25280 N VAL N 69 26.586 28.601 71.611 1.00 79.62 N +ATOM 25281 CA VAL N 69 27.086 27.528 72.461 1.00 87.38 C +ATOM 25282 C VAL N 69 27.438 28.082 73.840 1.00102.58 C +ATOM 25283 O VAL N 69 27.059 27.510 74.875 1.00133.53 O +ATOM 25284 CB VAL N 69 28.334 26.852 71.890 1.00 96.56 C +ATOM 25285 CG1 VAL N 69 28.898 25.879 72.913 1.00128.52 C +ATOM 25286 CG2 VAL N 69 28.036 26.109 70.600 1.00 84.27 C +ATOM 25287 N THR N 70 28.095 29.234 73.851 1.00101.65 N +ATOM 25288 CA THR N 70 28.420 29.907 75.100 1.00115.09 C +ATOM 25289 C THR N 70 27.177 30.306 75.903 1.00113.21 C +ATOM 25290 O THR N 70 27.114 30.079 77.129 1.00140.18 O +ATOM 25291 CB THR N 70 29.273 31.148 74.830 1.00127.39 C +ATOM 25292 OG1 THR N 70 30.410 30.750 74.052 1.00135.66 O +ATOM 25293 CG2 THR N 70 29.738 31.800 76.152 1.00131.32 C +ATOM 25294 N ALA N 71 26.191 30.898 75.227 1.00100.24 N +ATOM 25295 CA ALA N 71 24.929 31.244 75.889 1.00109.95 C +ATOM 25296 C ALA N 71 24.186 30.010 76.449 1.00102.75 C +ATOM 25297 O ALA N 71 23.708 30.019 77.603 1.00133.07 O +ATOM 25298 CB ALA N 71 24.021 31.987 74.940 1.00103.71 C +ATOM 25299 N LEU N 72 24.154 28.939 75.664 1.00 85.70 N +ATOM 25300 CA LEU N 72 23.614 27.659 76.141 1.00 91.22 C +ATOM 25301 C LEU N 72 24.330 27.118 77.393 1.00109.24 C +ATOM 25302 O LEU N 72 23.735 26.400 78.195 1.00 89.08 O +ATOM 25303 CB LEU N 72 23.676 26.589 75.049 1.00 75.09 C +ATOM 25304 CG LEU N 72 22.790 26.878 73.852 1.00 76.25 C +ATOM 25305 CD1 LEU N 72 23.237 26.017 72.708 1.00 85.89 C +ATOM 25306 CD2 LEU N 72 21.334 26.611 74.153 1.00102.48 C +ATOM 25307 N LYS N 73 25.603 27.466 77.559 1.00118.72 N +ATOM 25308 CA LYS N 73 26.350 27.009 78.728 1.00111.32 C +ATOM 25309 C LYS N 73 26.132 27.901 79.934 1.00110.46 C +ATOM 25310 O LYS N 73 25.904 27.409 81.033 1.00103.29 O +ATOM 25311 CB LYS N 73 27.835 26.961 78.433 1.00116.94 C +ATOM 25312 CG LYS N 73 28.605 26.268 79.522 1.00114.46 C +ATOM 25313 CD LYS N 73 30.007 26.798 79.554 1.00134.51 C +ATOM 25314 CE LYS N 73 30.154 28.160 80.272 1.00126.22 C +ATOM 25315 NZ LYS N 73 30.766 28.013 81.626 1.00135.55 N +ATOM 25316 N ASP N 74 26.201 29.216 79.717 1.00108.97 N +ATOM 25317 CA ASP N 74 26.036 30.192 80.793 1.00112.19 C +ATOM 25318 C ASP N 74 24.672 30.067 81.485 1.00124.58 C +ATOM 25319 O ASP N 74 24.557 30.356 82.684 1.00183.58 O +ATOM 25320 CB ASP N 74 26.210 31.631 80.277 1.00103.03 C +ATOM 25321 CG ASP N 74 27.645 31.944 79.851 1.00112.79 C +ATOM 25322 OD1 ASP N 74 28.613 31.324 80.374 1.00100.01 O +ATOM 25323 OD2 ASP N 74 27.791 32.807 78.959 1.00106.30 O +ATOM 25324 N SER N 75 23.661 29.598 80.749 1.00106.66 N +ATOM 25325 CA SER N 75 22.291 29.458 81.281 1.00 96.95 C +ATOM 25326 C SER N 75 22.189 28.426 82.410 1.00108.12 C +ATOM 25327 O SER N 75 21.288 28.505 83.241 1.00108.82 O +ATOM 25328 CB SER N 75 21.321 29.063 80.171 1.00 85.02 C +ATOM 25329 OG SER N 75 21.301 27.654 79.987 1.00 72.59 O +ATOM 25330 N ARG N 76 23.133 27.484 82.440 1.00129.42 N +ATOM 25331 CA ARG N 76 23.176 26.413 83.449 1.00131.44 C +ATOM 25332 C ARG N 76 21.927 25.524 83.269 1.00117.28 C +ATOM 25333 O ARG N 76 21.391 24.989 84.230 1.00156.20 O +ATOM 25334 CB ARG N 76 23.356 26.970 84.915 1.00131.98 C +ATOM 25335 CG ARG N 76 23.112 25.933 85.975 1.00156.54 C +ATOM 25336 CD ARG N 76 23.796 24.583 85.835 1.00158.49 C +ATOM 25337 NE ARG N 76 25.193 24.560 86.372 1.00159.70 N +ATOM 25338 CZ ARG N 76 26.270 24.616 85.579 1.00145.97 C +ATOM 25339 NH1 ARG N 76 26.136 24.714 84.249 1.00143.84 N +ATOM 25340 NH2 ARG N 76 27.492 24.633 86.110 1.00109.86 N +ATOM 25341 N TRP N 77 21.496 25.360 82.026 1.00 99.85 N +ATOM 25342 CA TRP N 77 20.458 24.406 81.679 1.00103.27 C +ATOM 25343 C TRP N 77 20.997 23.294 80.767 1.00118.46 C +ATOM 25344 O TRP N 77 20.542 22.146 80.823 1.00 99.21 O +ATOM 25345 CB TRP N 77 19.321 25.144 80.966 1.00118.16 C +ATOM 25346 CG TRP N 77 18.240 25.617 81.884 1.00114.93 C +ATOM 25347 CD1 TRP N 77 18.274 26.702 82.691 1.00 94.46 C +ATOM 25348 CD2 TRP N 77 16.930 25.050 82.021 1.00123.13 C +ATOM 25349 NE1 TRP N 77 17.083 26.836 83.346 1.00 99.60 N +ATOM 25350 CE2 TRP N 77 16.248 25.819 82.966 1.00112.22 C +ATOM 25351 CE3 TRP N 77 16.275 23.953 81.438 1.00140.61 C +ATOM 25352 CZ2 TRP N 77 14.944 25.531 83.355 1.00136.51 C +ATOM 25353 CZ3 TRP N 77 14.979 23.669 81.826 1.00131.81 C +ATOM 25354 CH2 TRP N 77 14.327 24.453 82.776 1.00127.97 C +ATOM 25355 N PHE N 78 21.969 23.653 79.926 1.00142.71 N +ATOM 25356 CA PHE N 78 22.500 22.768 78.881 1.00116.78 C +ATOM 25357 C PHE N 78 24.004 22.508 79.022 1.00114.02 C +ATOM 25358 O PHE N 78 24.767 23.417 79.385 1.00104.69 O +ATOM 25359 CB PHE N 78 22.282 23.402 77.520 1.00 99.37 C +ATOM 25360 CG PHE N 78 20.862 23.765 77.246 1.00102.87 C +ATOM 25361 CD1 PHE N 78 19.926 22.786 76.935 1.00123.01 C +ATOM 25362 CD2 PHE N 78 20.465 25.081 77.262 1.00 94.60 C +ATOM 25363 CE1 PHE N 78 18.620 23.122 76.638 1.00132.70 C +ATOM 25364 CE2 PHE N 78 19.162 25.428 76.951 1.00113.00 C +ATOM 25365 CZ PHE N 78 18.238 24.448 76.644 1.00123.30 C +ATOM 25366 N ILE N 79 24.411 21.274 78.721 1.00100.40 N +ATOM 25367 CA ILE N 79 25.807 20.931 78.463 1.00 96.27 C +ATOM 25368 C ILE N 79 25.983 20.913 76.943 1.00112.14 C +ATOM 25369 O ILE N 79 25.212 20.239 76.249 1.00 96.64 O +ATOM 25370 CB ILE N 79 26.137 19.531 78.974 1.00 96.16 C +ATOM 25371 CG1 ILE N 79 25.665 19.353 80.408 1.00111.86 C +ATOM 25372 CG2 ILE N 79 27.629 19.266 78.884 1.00 94.02 C +ATOM 25373 CD1 ILE N 79 25.436 17.904 80.802 1.00131.92 C +ATOM 25374 N PRO N 80 26.911 21.738 76.415 1.00118.28 N +ATOM 25375 CA PRO N 80 27.062 21.719 74.976 1.00 99.61 C +ATOM 25376 C PRO N 80 28.109 20.728 74.576 1.00114.05 C +ATOM 25377 O PRO N 80 29.138 20.609 75.251 1.00123.61 O +ATOM 25378 CB PRO N 80 27.529 23.122 74.648 1.00 89.57 C +ATOM 25379 CG PRO N 80 27.049 23.948 75.773 1.00128.19 C +ATOM 25380 CD PRO N 80 27.271 23.057 76.962 1.00138.58 C +ATOM 25381 N LEU N 81 27.770 19.908 73.590 1.00104.65 N +ATOM 25382 CA LEU N 81 28.693 18.944 73.066 1.00 88.17 C +ATOM 25383 C LEU N 81 29.362 19.579 71.878 1.00 92.80 C +ATOM 25384 O LEU N 81 28.700 20.322 71.117 1.00 79.09 O +ATOM 25385 CB LEU N 81 27.974 17.664 72.691 1.00 70.78 C +ATOM 25386 CG LEU N 81 27.230 17.082 73.878 1.00 77.68 C +ATOM 25387 CD1 LEU N 81 26.459 15.870 73.434 1.00 57.20 C +ATOM 25388 CD2 LEU N 81 28.204 16.698 74.989 1.00105.53 C +ATOM 25389 N GLU N 82 30.686 19.341 71.786 1.00 84.71 N +ATOM 25390 CA GLU N 82 31.544 19.953 70.764 1.00 67.96 C +ATOM 25391 C GLU N 82 31.394 19.277 69.387 1.00 65.83 C +ATOM 25392 O GLU N 82 31.782 18.129 69.194 1.00 34.86 O +ATOM 25393 CB GLU N 82 33.009 19.966 71.178 1.00 53.94 C +ATOM 25394 CG GLU N 82 33.918 20.602 70.150 1.00 70.85 C +ATOM 25395 CD GLU N 82 33.753 22.143 70.025 1.00101.39 C +ATOM 25396 OE1 GLU N 82 32.617 22.684 69.825 1.00 95.64 O +ATOM 25397 OE2 GLU N 82 34.807 22.833 69.941 1.00153.27 O +ATOM 25398 N ARG N 83 30.687 19.986 68.497 1.00 71.80 N +ATOM 25399 CA ARG N 83 30.508 19.559 67.137 1.00 63.50 C +ATOM 25400 C ARG N 83 31.042 20.590 66.130 1.00 75.48 C +ATOM 25401 O ARG N 83 31.346 20.228 64.990 1.00 85.45 O +ATOM 25402 CB ARG N 83 29.028 19.274 66.857 1.00 64.61 C +ATOM 25403 CG ARG N 83 28.409 18.245 67.778 1.00 56.38 C +ATOM 25404 CD ARG N 83 28.959 16.851 67.542 1.00 51.31 C +ATOM 25405 NE ARG N 83 28.154 15.891 68.283 1.00 66.14 N +ATOM 25406 CZ ARG N 83 28.469 15.360 69.474 1.00100.13 C +ATOM 25407 NH1 ARG N 83 29.655 15.570 70.035 1.00104.91 N +ATOM 25408 NH2 ARG N 83 27.591 14.569 70.085 1.00124.96 N +ATOM 25409 N GLN N 84 31.168 21.861 66.507 1.00 77.66 N +ATOM 25410 CA GLN N 84 31.750 22.819 65.558 1.00 86.49 C +ATOM 25411 C GLN N 84 33.133 22.338 65.081 1.00 87.68 C +ATOM 25412 O GLN N 84 33.460 22.430 63.919 1.00 89.25 O +ATOM 25413 CB GLN N 84 31.817 24.247 66.123 1.00100.55 C +ATOM 25414 CG GLN N 84 31.647 25.350 65.070 1.00 99.39 C +ATOM 25415 CD GLN N 84 31.792 26.760 65.646 1.00122.07 C +ATOM 25416 OE1 GLN N 84 31.425 27.016 66.787 1.00122.61 O +ATOM 25417 NE2 GLN N 84 32.394 27.661 64.873 1.00133.27 N +ATOM 25418 N GLY N 85 33.960 21.825 65.979 1.00103.92 N +ATOM 25419 CA GLY N 85 35.281 21.347 65.564 1.00 98.48 C +ATOM 25420 C GLY N 85 35.389 19.832 65.614 1.00 91.53 C +ATOM 25421 O GLY N 85 36.421 19.297 66.028 1.00 51.98 O +ATOM 25422 N LEU N 86 34.331 19.132 65.193 1.00 83.87 N +ATOM 25423 CA LEU N 86 34.224 17.689 65.452 1.00 76.12 C +ATOM 25424 C LEU N 86 35.403 16.938 64.850 1.00 78.41 C +ATOM 25425 O LEU N 86 35.864 15.933 65.390 1.00 67.56 O +ATOM 25426 CB LEU N 86 32.898 17.135 64.908 1.00 66.03 C +ATOM 25427 CG LEU N 86 32.631 15.621 64.887 1.00 59.76 C +ATOM 25428 CD1 LEU N 86 32.696 15.005 66.272 1.00 69.93 C +ATOM 25429 CD2 LEU N 86 31.277 15.319 64.277 1.00 55.72 C +ATOM 25430 N GLN N 87 35.878 17.423 63.712 1.00 99.68 N +ATOM 25431 CA GLN N 87 36.897 16.709 62.969 1.00103.22 C +ATOM 25432 C GLN N 87 38.167 16.577 63.815 1.00 85.92 C +ATOM 25433 O GLN N 87 38.821 15.508 63.849 1.00 95.26 O +ATOM 25434 CB GLN N 87 37.151 17.407 61.619 1.00103.79 C +ATOM 25435 CG GLN N 87 37.512 16.435 60.500 1.00107.00 C +ATOM 25436 CD GLN N 87 36.663 15.152 60.532 1.00 95.36 C +ATOM 25437 OE1 GLN N 87 35.439 15.210 60.376 1.00 95.14 O +ATOM 25438 NE2 GLN N 87 37.320 13.992 60.627 1.00 74.53 N +ATOM 25439 N ASN N 88 38.523 17.661 64.490 1.00 69.40 N +ATOM 25440 CA ASN N 88 39.748 17.677 65.304 1.00 97.23 C +ATOM 25441 C ASN N 88 39.622 16.745 66.495 1.00 86.85 C +ATOM 25442 O ASN N 88 40.597 16.141 66.941 1.00 96.68 O +ATOM 25443 CB ASN N 88 40.027 19.084 65.820 1.00102.58 C +ATOM 25444 CG ASN N 88 40.160 20.088 64.711 1.00106.75 C +ATOM 25445 OD1 ASN N 88 40.729 19.786 63.670 1.00 94.23 O +ATOM 25446 ND2 ASN N 88 39.595 21.283 64.910 1.00136.81 N +ATOM 25447 N LEU N 89 38.406 16.655 67.003 1.00 69.26 N +ATOM 25448 CA LEU N 89 38.139 15.860 68.169 1.00 60.66 C +ATOM 25449 C LEU N 89 38.354 14.414 67.794 1.00 77.91 C +ATOM 25450 O LEU N 89 39.005 13.638 68.506 1.00 94.64 O +ATOM 25451 CB LEU N 89 36.697 16.105 68.574 1.00 57.02 C +ATOM 25452 CG LEU N 89 36.318 15.945 70.034 1.00 46.95 C +ATOM 25453 CD1 LEU N 89 35.336 14.812 70.182 1.00 44.57 C +ATOM 25454 CD2 LEU N 89 37.522 15.722 70.917 1.00 43.72 C +ATOM 25455 N LEU N 90 37.885 14.058 66.601 1.00 97.95 N +ATOM 25456 CA LEU N 90 38.018 12.670 66.110 1.00 98.26 C +ATOM 25457 C LEU N 90 39.483 12.321 65.790 1.00 93.24 C +ATOM 25458 O LEU N 90 39.921 11.171 65.938 1.00 63.47 O +ATOM 25459 CB LEU N 90 37.147 12.457 64.869 1.00 71.63 C +ATOM 25460 CG LEU N 90 35.667 12.697 65.086 1.00 50.37 C +ATOM 25461 CD1 LEU N 90 34.995 12.909 63.751 1.00 40.65 C +ATOM 25462 CD2 LEU N 90 35.078 11.519 65.838 1.00 61.01 C +ATOM 25463 N ASN N 91 40.229 13.343 65.379 1.00 81.71 N +ATOM 25464 CA ASN N 91 41.628 13.182 65.103 1.00 87.53 C +ATOM 25465 C ASN N 91 42.407 12.878 66.380 1.00 97.63 C +ATOM 25466 O ASN N 91 43.253 11.974 66.405 1.00 94.93 O +ATOM 25467 CB ASN N 91 42.174 14.429 64.397 1.00 78.65 C +ATOM 25468 CG ASN N 91 42.880 14.072 63.123 1.00103.14 C +ATOM 25469 OD1 ASN N 91 42.329 13.279 62.324 1.00125.58 O +ATOM 25470 ND2 ASN N 91 44.173 14.430 63.028 1.00105.87 N +ATOM 25471 N GLU N 92 42.195 13.688 67.412 1.00108.17 N +ATOM 25472 CA GLU N 92 42.913 13.484 68.673 1.00 93.07 C +ATOM 25473 C GLU N 92 42.619 12.082 69.184 1.00 89.95 C +ATOM 25474 O GLU N 92 43.458 11.438 69.807 1.00 56.48 O +ATOM 25475 CB GLU N 92 42.520 14.555 69.699 1.00 82.21 C +ATOM 25476 CG GLU N 92 43.456 15.749 69.744 1.00 83.81 C +ATOM 25477 CD GLU N 92 44.935 15.355 69.922 1.00 95.92 C +ATOM 25478 OE1 GLU N 92 45.320 14.700 70.927 1.00 73.07 O +ATOM 25479 OE2 GLU N 92 45.753 15.789 69.085 1.00122.44 O +ATOM 25480 N ARG N 93 41.388 11.640 68.957 1.00 90.60 N +ATOM 25481 CA ARG N 93 40.985 10.332 69.420 1.00 94.85 C +ATOM 25482 C ARG N 93 41.698 9.246 68.617 1.00 95.41 C +ATOM 25483 O ARG N 93 42.035 8.189 69.152 1.00 74.27 O +ATOM 25484 CB ARG N 93 39.451 10.217 69.389 1.00 90.39 C +ATOM 25485 CG ARG N 93 38.811 11.090 70.471 1.00 94.61 C +ATOM 25486 CD ARG N 93 37.322 11.290 70.298 1.00104.90 C +ATOM 25487 NE ARG N 93 36.553 10.427 71.184 1.00 80.12 N +ATOM 25488 CZ ARG N 93 36.057 9.240 70.842 1.00 65.98 C +ATOM 25489 NH1 ARG N 93 36.242 8.716 69.631 1.00 61.27 N +ATOM 25490 NH2 ARG N 93 35.314 8.609 71.723 1.00 67.79 N +ATOM 25491 N LYS N 94 41.964 9.515 67.341 1.00101.40 N +ATOM 25492 CA LYS N 94 42.748 8.576 66.524 1.00 84.40 C +ATOM 25493 C LYS N 94 44.155 8.475 67.084 1.00 77.48 C +ATOM 25494 O LYS N 94 44.714 7.370 67.163 1.00 65.60 O +ATOM 25495 CB LYS N 94 42.840 9.049 65.076 1.00 79.23 C +ATOM 25496 CG LYS N 94 41.726 8.584 64.152 1.00 77.34 C +ATOM 25497 CD LYS N 94 41.840 9.288 62.810 1.00 83.90 C +ATOM 25498 CE LYS N 94 41.108 8.555 61.695 1.00 87.12 C +ATOM 25499 NZ LYS N 94 40.960 9.448 60.511 1.00 95.27 N +ATOM 25500 N ILE N 95 44.705 9.622 67.505 1.00 65.49 N +ATOM 25501 CA ILE N 95 46.090 9.649 67.959 1.00 58.91 C +ATOM 25502 C ILE N 95 46.203 8.945 69.278 1.00 65.66 C +ATOM 25503 O ILE N 95 47.228 8.239 69.535 1.00 48.17 O +ATOM 25504 CB ILE N 95 46.660 11.055 68.136 1.00 53.81 C +ATOM 25505 CG1 ILE N 95 46.385 11.915 66.906 1.00 70.51 C +ATOM 25506 CG2 ILE N 95 48.171 10.924 68.300 1.00 49.58 C +ATOM 25507 CD1 ILE N 95 47.187 13.218 66.806 1.00 58.57 C +ATOM 25508 N ILE N 96 45.168 9.170 70.126 1.00 51.93 N +ATOM 25509 CA ILE N 96 45.064 8.486 71.412 1.00 40.98 C +ATOM 25510 C ILE N 96 45.070 6.991 71.210 1.00 38.13 C +ATOM 25511 O ILE N 96 45.954 6.288 71.700 1.00 33.63 O +ATOM 25512 CB ILE N 96 43.817 8.872 72.166 1.00 37.87 C +ATOM 25513 CG1 ILE N 96 43.887 10.323 72.633 1.00 44.03 C +ATOM 25514 CG2 ILE N 96 43.714 7.997 73.411 1.00 45.80 C +ATOM 25515 CD1 ILE N 96 42.702 10.776 73.477 1.00 43.26 C +ATOM 25516 N ARG N 97 44.129 6.519 70.418 1.00 43.51 N +ATOM 25517 CA ARG N 97 43.976 5.084 70.209 1.00 60.15 C +ATOM 25518 C ARG N 97 45.230 4.483 69.596 1.00 67.87 C +ATOM 25519 O ARG N 97 45.538 3.304 69.822 1.00 93.43 O +ATOM 25520 CB ARG N 97 42.750 4.782 69.325 1.00 84.49 C +ATOM 25521 CG ARG N 97 41.515 4.272 70.080 1.00 78.53 C +ATOM 25522 CD ARG N 97 40.384 3.941 69.122 1.00 75.86 C +ATOM 25523 NE ARG N 97 39.649 5.129 68.709 1.00 78.61 N +ATOM 25524 CZ ARG N 97 38.496 5.525 69.237 1.00 97.51 C +ATOM 25525 NH1 ARG N 97 37.930 4.838 70.221 1.00 83.25 N +ATOM 25526 NH2 ARG N 97 37.912 6.633 68.778 1.00118.67 N +ATOM 25527 N ALA N 98 45.936 5.263 68.782 1.00 70.88 N +ATOM 25528 CA ALA N 98 47.148 4.769 68.151 1.00 79.20 C +ATOM 25529 C ALA N 98 48.281 4.715 69.175 1.00 85.04 C +ATOM 25530 O ALA N 98 49.200 3.886 69.050 1.00 73.29 O +ATOM 25531 CB ALA N 98 47.516 5.653 66.980 1.00 92.10 C +ATOM 25532 N ALA N 99 48.202 5.593 70.189 1.00 85.68 N +ATOM 25533 CA ALA N 99 49.222 5.686 71.270 1.00 76.70 C +ATOM 25534 C ALA N 99 49.205 4.526 72.219 1.00 85.31 C +ATOM 25535 O ALA N 99 50.211 3.833 72.406 1.00137.18 O +ATOM 25536 CB ALA N 99 49.013 6.925 72.072 1.00 78.03 C +ATOM 25537 N GLN N 100 48.007 4.190 72.682 1.00105.31 N +ATOM 25538 CA GLN N 100 47.863 3.226 73.777 1.00106.23 C +ATOM 25539 C GLN N 100 47.351 1.825 73.389 1.00 99.24 C +ATOM 25540 O GLN N 100 47.115 0.985 74.263 1.00110.27 O +ATOM 25541 CB GLN N 100 46.972 3.818 74.865 1.00 88.59 C +ATOM 25542 CG GLN N 100 45.717 4.496 74.354 1.00 72.42 C +ATOM 25543 CD GLN N 100 45.230 5.593 75.265 1.00 62.21 C +ATOM 25544 OE1 GLN N 100 45.937 6.588 75.548 1.00 54.64 O +ATOM 25545 NE2 GLN N 100 43.997 5.435 75.724 1.00 56.73 N +ATOM 25546 N GLU N 101 47.237 1.553 72.089 1.00 90.66 N +ATOM 25547 CA GLU N 101 46.731 0.258 71.625 1.00 92.29 C +ATOM 25548 C GLU N 101 47.678 -0.899 71.935 1.00 98.30 C +ATOM 25549 O GLU N 101 47.249 -2.051 72.027 1.00 78.05 O +ATOM 25550 CB GLU N 101 46.421 0.294 70.129 1.00101.84 C +ATOM 25551 CG GLU N 101 47.562 0.791 69.250 1.00108.36 C +ATOM 25552 CD GLU N 101 47.223 0.729 67.766 1.00112.00 C +ATOM 25553 OE1 GLU N 101 46.021 0.634 67.433 1.00111.04 O +ATOM 25554 OE2 GLU N 101 48.153 0.791 66.931 1.00107.60 O +ATOM 25555 N ASN N 102 48.961 -0.601 72.117 1.00113.25 N +ATOM 25556 CA ASN N 102 49.944 -1.649 72.367 1.00107.64 C +ATOM 25557 C ASN N 102 50.200 -1.907 73.834 1.00 97.97 C +ATOM 25558 O ASN N 102 50.976 -2.799 74.181 1.00108.90 O +ATOM 25559 CB ASN N 102 51.252 -1.302 71.683 1.00113.33 C +ATOM 25560 CG ASN N 102 51.148 -1.424 70.182 1.00121.77 C +ATOM 25561 OD1 ASN N 102 51.219 -2.533 69.620 1.00 94.04 O +ATOM 25562 ND2 ASN N 102 50.961 -0.287 69.517 1.00130.78 N +ATOM 25563 N GLY N 103 49.562 -1.131 74.701 1.00 90.61 N +ATOM 25564 CA GLY N 103 49.735 -1.315 76.135 1.00100.50 C +ATOM 25565 C GLY N 103 51.170 -1.132 76.596 1.00102.29 C +ATOM 25566 O GLY N 103 51.636 -1.791 77.542 1.00115.37 O +ATOM 25567 N THR N 104 51.880 -0.229 75.938 1.00 87.81 N +ATOM 25568 CA THR N 104 53.156 0.213 76.449 1.00 82.25 C +ATOM 25569 C THR N 104 52.977 1.543 77.183 1.00 71.85 C +ATOM 25570 O THR N 104 53.748 1.855 78.074 1.00 83.72 O +ATOM 25571 CB THR N 104 54.230 0.317 75.334 1.00 74.88 C +ATOM 25572 OG1 THR N 104 53.868 1.336 74.392 1.00 63.56 O +ATOM 25573 CG2 THR N 104 54.395 -1.019 74.629 1.00 68.63 C +ATOM 25574 N VAL N 105 51.960 2.315 76.826 1.00 75.42 N +ATOM 25575 CA VAL N 105 51.867 3.706 77.310 1.00116.07 C +ATOM 25576 C VAL N 105 51.735 3.709 78.823 1.00130.90 C +ATOM 25577 O VAL N 105 51.051 2.849 79.398 1.00135.56 O +ATOM 25578 CB VAL N 105 50.721 4.531 76.622 1.00146.91 C +ATOM 25579 CG1 VAL N 105 50.069 5.517 77.589 1.00127.26 C +ATOM 25580 CG2 VAL N 105 51.247 5.282 75.381 1.00139.23 C +ATOM 25581 N ALA N 106 52.416 4.674 79.442 1.00150.49 N +ATOM 25582 CA ALA N 106 52.548 4.758 80.890 1.00156.88 C +ATOM 25583 C ALA N 106 51.186 4.933 81.557 1.00166.90 C +ATOM 25584 O ALA N 106 50.369 5.749 81.124 1.00179.10 O +ATOM 25585 CB ALA N 106 53.472 5.909 81.260 1.00139.35 C +ATOM 25586 N ILE N 107 50.954 4.160 82.613 1.00151.35 N +ATOM 25587 CA ILE N 107 49.644 4.099 83.268 1.00135.97 C +ATOM 25588 C ILE N 107 49.173 5.474 83.792 1.00122.60 C +ATOM 25589 O ILE N 107 47.974 5.759 83.843 1.00 99.44 O +ATOM 25590 CB ILE N 107 49.664 3.049 84.413 1.00117.19 C +ATOM 25591 CG1 ILE N 107 48.245 2.744 84.910 1.00104.14 C +ATOM 25592 CG2 ILE N 107 50.552 3.518 85.562 1.00120.66 C +ATOM 25593 CD1 ILE N 107 47.287 2.249 83.845 1.00 94.39 C +ATOM 25594 N ASN N 108 50.125 6.320 84.172 1.00125.10 N +ATOM 25595 CA ASN N 108 49.832 7.695 84.594 1.00143.43 C +ATOM 25596 C ASN N 108 49.393 8.552 83.412 1.00147.33 C +ATOM 25597 O ASN N 108 48.559 9.446 83.547 1.00141.80 O +ATOM 25598 CB ASN N 108 51.070 8.337 85.228 1.00158.63 C +ATOM 25599 CG ASN N 108 51.961 7.323 85.925 1.00178.76 C +ATOM 25600 OD1 ASN N 108 51.761 7.011 87.097 1.00197.22 O +ATOM 25601 ND2 ASN N 108 52.954 6.805 85.203 1.00178.57 N +ATOM 25602 N ASN N 109 49.985 8.275 82.258 1.00137.06 N +ATOM 25603 CA ASN N 109 49.770 9.069 81.058 1.00141.22 C +ATOM 25604 C ASN N 109 48.548 8.626 80.252 1.00132.94 C +ATOM 25605 O ASN N 109 48.054 9.372 79.398 1.00115.05 O +ATOM 25606 CB ASN N 109 51.020 9.007 80.178 1.00145.17 C +ATOM 25607 CG ASN N 109 51.683 10.358 80.018 1.00156.50 C +ATOM 25608 OD1 ASN N 109 51.707 10.922 78.920 1.00124.12 O +ATOM 25609 ND2 ASN N 109 52.193 10.906 81.120 1.00159.05 N +ATOM 25610 N ARG N 110 48.069 7.414 80.538 1.00128.52 N +ATOM 25611 CA ARG N 110 46.993 6.762 79.769 1.00104.55 C +ATOM 25612 C ARG N 110 45.725 7.626 79.724 1.00 94.90 C +ATOM 25613 O ARG N 110 45.308 8.184 80.740 1.00112.78 O +ATOM 25614 CB ARG N 110 46.663 5.411 80.417 1.00 89.76 C +ATOM 25615 CG ARG N 110 46.007 4.411 79.497 1.00 98.18 C +ATOM 25616 CD ARG N 110 46.426 2.988 79.832 1.00104.68 C +ATOM 25617 NE ARG N 110 45.543 2.373 80.830 1.00118.36 N +ATOM 25618 CZ ARG N 110 44.800 1.277 80.632 1.00136.93 C +ATOM 25619 NH1 ARG N 110 44.813 0.624 79.464 1.00141.68 N +ATOM 25620 NH2 ARG N 110 44.045 0.810 81.626 1.00136.33 N +ATOM 25621 N ILE N 111 45.117 7.751 78.550 1.00 83.69 N +ATOM 25622 CA ILE N 111 43.845 8.470 78.429 1.00 82.53 C +ATOM 25623 C ILE N 111 42.726 7.498 78.139 1.00 94.13 C +ATOM 25624 O ILE N 111 42.731 6.866 77.085 1.00108.17 O +ATOM 25625 CB ILE N 111 43.867 9.517 77.303 1.00 78.25 C +ATOM 25626 CG1 ILE N 111 44.893 10.602 77.637 1.00 94.90 C +ATOM 25627 CG2 ILE N 111 42.483 10.127 77.122 1.00 71.80 C +ATOM 25628 CD1 ILE N 111 45.221 11.536 76.485 1.00110.97 C +ATOM 25629 N PRO N 112 41.757 7.383 79.060 1.00105.08 N +ATOM 25630 CA PRO N 112 40.670 6.438 78.859 1.00103.99 C +ATOM 25631 C PRO N 112 39.627 7.014 77.893 1.00 97.31 C +ATOM 25632 O PRO N 112 39.157 8.144 78.076 1.00 64.29 O +ATOM 25633 CB PRO N 112 40.104 6.271 80.268 1.00 98.06 C +ATOM 25634 CG PRO N 112 40.329 7.609 80.907 1.00 96.29 C +ATOM 25635 CD PRO N 112 41.545 8.217 80.259 1.00 96.39 C +ATOM 25636 N LEU N 113 39.261 6.217 76.898 1.00107.05 N +ATOM 25637 CA LEU N 113 38.373 6.664 75.843 1.00115.75 C +ATOM 25638 C LEU N 113 36.986 6.047 75.935 1.00 89.42 C +ATOM 25639 O LEU N 113 36.802 4.835 76.133 1.00 71.80 O +ATOM 25640 CB LEU N 113 38.977 6.366 74.467 1.00145.04 C +ATOM 25641 CG LEU N 113 39.927 7.427 73.928 1.00137.25 C +ATOM 25642 CD1 LEU N 113 40.338 7.002 72.529 1.00132.90 C +ATOM 25643 CD2 LEU N 113 39.304 8.821 73.907 1.00120.98 C +ATOM 25644 N GLN N 114 36.020 6.896 75.657 1.00 82.75 N +ATOM 25645 CA GLN N 114 34.639 6.589 75.880 1.00104.72 C +ATOM 25646 C GLN N 114 33.903 7.141 74.699 1.00 98.14 C +ATOM 25647 O GLN N 114 34.379 8.093 74.078 1.00145.11 O +ATOM 25648 CB GLN N 114 34.186 7.292 77.145 1.00108.55 C +ATOM 25649 CG GLN N 114 33.067 6.593 77.868 1.00115.25 C +ATOM 25650 CD GLN N 114 32.200 7.588 78.562 1.00111.15 C +ATOM 25651 OE1 GLN N 114 32.698 8.617 79.047 1.00132.15 O +ATOM 25652 NE2 GLN N 114 30.893 7.296 78.639 1.00107.04 N +ATOM 25653 N SER N 115 32.818 6.483 74.319 1.00 97.79 N +ATOM 25654 CA SER N 115 32.094 6.838 73.101 1.00119.86 C +ATOM 25655 C SER N 115 31.662 8.275 73.196 1.00105.85 C +ATOM 25656 O SER N 115 31.568 8.837 74.305 1.00 99.46 O +ATOM 25657 CB SER N 115 30.862 5.944 72.917 1.00135.19 C +ATOM 25658 OG SER N 115 30.076 5.897 74.102 1.00115.25 O +ATOM 25659 N LEU N 116 31.434 8.909 72.054 1.00 97.79 N +ATOM 25660 CA LEU N 116 31.287 10.365 72.100 1.00147.77 C +ATOM 25661 C LEU N 116 29.911 10.644 72.665 1.00140.00 C +ATOM 25662 O LEU N 116 28.951 10.043 72.207 1.00105.98 O +ATOM 25663 CB LEU N 116 31.421 11.008 70.719 1.00159.22 C +ATOM 25664 CG LEU N 116 32.802 10.965 70.056 1.00120.82 C +ATOM 25665 CD1 LEU N 116 32.921 9.753 69.120 1.00120.66 C +ATOM 25666 CD2 LEU N 116 33.025 12.264 69.317 1.00 82.20 C +ATOM 25667 N THR N 117 29.848 11.449 73.726 1.00138.39 N +ATOM 25668 CA THR N 117 28.591 11.742 74.401 1.00111.18 C +ATOM 25669 C THR N 117 27.676 12.309 73.354 1.00 99.83 C +ATOM 25670 O THR N 117 28.087 13.194 72.602 1.00 83.34 O +ATOM 25671 CB THR N 117 28.772 12.775 75.532 1.00113.87 C +ATOM 25672 OG1 THR N 117 29.769 12.326 76.456 1.00 90.49 O +ATOM 25673 CG2 THR N 117 27.467 12.974 76.285 1.00122.27 C +ATOM 25674 N ALA N 118 26.441 11.819 73.336 1.00 87.34 N +ATOM 25675 CA ALA N 118 25.504 12.133 72.257 1.00 80.37 C +ATOM 25676 C ALA N 118 24.314 12.931 72.725 1.00 79.01 C +ATOM 25677 O ALA N 118 23.767 12.670 73.809 1.00139.12 O +ATOM 25678 CB ALA N 118 25.014 10.864 71.616 1.00 63.91 C +ATOM 25679 N ALA N 119 23.870 13.840 71.872 1.00 75.56 N +ATOM 25680 CA ALA N 119 22.872 14.848 72.253 1.00109.43 C +ATOM 25681 C ALA N 119 21.490 14.346 71.949 1.00119.55 C +ATOM 25682 O ALA N 119 21.341 13.484 71.076 1.00106.24 O +ATOM 25683 CB ALA N 119 23.116 16.148 71.500 1.00113.27 C +ATOM 25684 N ASN N 120 20.487 14.860 72.670 1.00114.32 N +ATOM 25685 CA ASN N 120 19.113 14.496 72.364 1.00129.92 C +ATOM 25686 C ASN N 120 18.413 15.543 71.527 1.00123.69 C +ATOM 25687 O ASN N 120 17.707 15.227 70.556 1.00138.94 O +ATOM 25688 CB ASN N 120 18.280 14.245 73.611 1.00157.02 C +ATOM 25689 CG ASN N 120 16.864 13.768 73.269 1.00200.15 C +ATOM 25690 OD1 ASN N 120 15.902 14.221 73.882 1.00269.87 O +ATOM 25691 ND2 ASN N 120 16.721 12.922 72.226 1.00171.31 N +ATOM 25692 N ILE N 121 18.548 16.796 71.928 1.00 99.86 N +ATOM 25693 CA ILE N 121 18.024 17.877 71.105 1.00126.77 C +ATOM 25694 C ILE N 121 19.207 18.631 70.545 1.00144.61 C +ATOM 25695 O ILE N 121 20.250 18.754 71.186 1.00162.77 O +ATOM 25696 CB ILE N 121 17.092 18.841 71.873 1.00111.37 C +ATOM 25697 CG1 ILE N 121 17.875 19.733 72.844 1.00124.79 C +ATOM 25698 CG2 ILE N 121 16.016 18.058 72.604 1.00105.04 C +ATOM 25699 CD1 ILE N 121 17.918 21.184 72.429 1.00124.87 C +ATOM 25700 N MET N 122 19.086 19.059 69.300 1.00122.52 N +ATOM 25701 CA MET N 122 20.072 19.959 68.782 1.00 84.51 C +ATOM 25702 C MET N 122 19.345 21.222 68.381 1.00 62.77 C +ATOM 25703 O MET N 122 18.252 21.177 67.870 1.00 51.39 O +ATOM 25704 CB MET N 122 20.898 19.288 67.654 1.00 88.82 C +ATOM 25705 CG MET N 122 20.119 18.730 66.478 1.00 76.37 C +ATOM 25706 SD MET N 122 21.183 18.697 65.018 1.00 97.75 S +ATOM 25707 CE MET N 122 19.991 19.348 63.798 1.00136.61 C +ATOM 25708 N VAL N 123 20.006 22.344 68.570 1.00 69.24 N +ATOM 25709 CA VAL N 123 19.443 23.627 68.194 1.00 79.18 C +ATOM 25710 C VAL N 123 20.286 24.336 67.155 1.00 77.71 C +ATOM 25711 O VAL N 123 21.500 24.484 67.305 1.00 77.97 O +ATOM 25712 CB VAL N 123 19.334 24.568 69.402 1.00117.06 C +ATOM 25713 CG1 VAL N 123 20.564 24.469 70.297 1.00127.27 C +ATOM 25714 CG2 VAL N 123 19.097 26.012 68.955 1.00141.95 C +ATOM 25715 N GLU N 124 19.646 24.736 66.072 1.00 79.23 N +ATOM 25716 CA GLU N 124 20.327 25.506 65.045 1.00 89.53 C +ATOM 25717 C GLU N 124 19.533 26.731 64.745 1.00 80.68 C +ATOM 25718 O GLU N 124 18.381 26.849 65.126 1.00 98.59 O +ATOM 25719 CB GLU N 124 20.563 24.689 63.754 1.00102.50 C +ATOM 25720 CG GLU N 124 19.556 23.593 63.456 1.00100.33 C +ATOM 25721 CD GLU N 124 20.085 22.604 62.437 1.00104.19 C +ATOM 25722 OE1 GLU N 124 21.301 22.283 62.475 1.00135.92 O +ATOM 25723 OE2 GLU N 124 19.285 22.102 61.640 1.00 95.81 O +ATOM 25724 N GLY N 125 20.133 27.608 63.965 1.00 92.61 N +ATOM 25725 CA GLY N 125 19.506 28.867 63.629 1.00 94.42 C +ATOM 25726 C GLY N 125 20.323 29.656 62.616 1.00 80.73 C +ATOM 25727 O GLY N 125 21.137 29.098 61.884 1.00 60.35 O +ATOM 25728 N SER N 126 20.053 30.946 62.534 1.00 70.28 N +ATOM 25729 CA SER N 126 20.639 31.754 61.493 1.00 80.83 C +ATOM 25730 C SER N 126 20.549 33.189 61.904 1.00 96.86 C +ATOM 25731 O SER N 126 19.590 33.597 62.557 1.00126.07 O +ATOM 25732 CB SER N 126 19.892 31.576 60.172 1.00 93.02 C +ATOM 25733 OG SER N 126 19.336 30.264 60.009 1.00133.86 O +ATOM 25734 N ILE N 127 21.520 33.980 61.491 1.00 96.96 N +ATOM 25735 CA ILE N 127 21.351 35.417 61.548 1.00 91.57 C +ATOM 25736 C ILE N 127 20.489 35.832 60.360 1.00101.54 C +ATOM 25737 O ILE N 127 20.942 35.871 59.230 1.00131.70 O +ATOM 25738 CB ILE N 127 22.683 36.170 61.526 1.00 98.13 C +ATOM 25739 CG1 ILE N 127 23.480 35.878 62.799 1.00 88.58 C +ATOM 25740 CG2 ILE N 127 22.447 37.671 61.387 1.00108.23 C +ATOM 25741 CD1 ILE N 127 24.991 35.928 62.600 1.00 95.45 C +ATOM 25742 N ILE N 128 19.221 36.091 60.633 1.00101.37 N +ATOM 25743 CA ILE N 128 18.231 36.466 59.620 1.00 85.01 C +ATOM 25744 C ILE N 128 18.243 37.975 59.641 1.00 80.61 C +ATOM 25745 O ILE N 128 17.745 38.641 60.557 1.00135.30 O +ATOM 25746 CB ILE N 128 16.839 35.863 59.946 1.00 98.81 C +ATOM 25747 CG1 ILE N 128 16.410 36.194 61.395 1.00132.71 C +ATOM 25748 CG2 ILE N 128 16.903 34.347 59.902 1.00118.07 C +ATOM 25749 CD1 ILE N 128 14.908 36.166 61.600 1.00126.46 C +ATOM 25750 N GLY N 129 18.964 38.535 58.705 1.00 84.05 N +ATOM 25751 CA GLY N 129 18.821 39.960 58.426 1.00105.97 C +ATOM 25752 C GLY N 129 19.634 40.953 59.252 1.00111.32 C +ATOM 25753 O GLY N 129 19.804 40.829 60.476 1.00 91.40 O +ATOM 25754 N TYR N 130 20.204 41.910 58.528 1.00106.35 N +ATOM 25755 CA TYR N 130 20.772 43.115 59.118 1.00 78.69 C +ATOM 25756 C TYR N 130 20.415 44.221 58.158 1.00101.65 C +ATOM 25757 O TYR N 130 20.906 44.256 57.035 1.00125.36 O +ATOM 25758 CB TYR N 130 22.284 43.004 59.270 1.00 66.84 C +ATOM 25759 CG TYR N 130 22.955 44.243 59.753 1.00 59.37 C +ATOM 25760 CD1 TYR N 130 23.214 45.297 58.870 1.00 63.77 C +ATOM 25761 CD2 TYR N 130 23.509 44.300 61.026 1.00 68.76 C +ATOM 25762 CE1 TYR N 130 23.901 46.435 59.278 1.00 83.24 C +ATOM 25763 CE2 TYR N 130 24.256 45.405 61.426 1.00 91.30 C +ATOM 25764 CZ TYR N 130 24.445 46.467 60.557 1.00 90.44 C +ATOM 25765 OH TYR N 130 25.054 47.607 61.021 1.00 81.63 O +ATOM 25766 N GLU N 131 19.434 45.024 58.531 1.00129.11 N +ATOM 25767 CA GLU N 131 19.101 46.207 57.753 1.00133.35 C +ATOM 25768 C GLU N 131 19.806 47.395 58.382 1.00121.52 C +ATOM 25769 O GLU N 131 20.064 47.402 59.593 1.00 94.09 O +ATOM 25770 CB GLU N 131 17.594 46.404 57.745 1.00175.03 C +ATOM 25771 CG GLU N 131 17.090 47.482 56.810 1.00196.09 C +ATOM 25772 CD GLU N 131 16.808 46.999 55.394 1.00213.16 C +ATOM 25773 OE1 GLU N 131 16.522 45.786 55.203 1.00264.71 O +ATOM 25774 OE2 GLU N 131 16.897 47.840 54.465 1.00139.93 O +ATOM 25775 N SER N 132 20.250 48.322 57.542 1.00116.27 N +ATOM 25776 CA SER N 132 21.133 49.388 58.008 1.00116.72 C +ATOM 25777 C SER N 132 20.483 50.764 57.845 1.00145.01 C +ATOM 25778 O SER N 132 19.814 51.023 56.838 1.00148.41 O +ATOM 25779 CB SER N 132 22.471 49.337 57.268 1.00109.67 C +ATOM 25780 OG SER N 132 22.623 50.459 56.418 1.00125.52 O +ATOM 25781 N ASN N 133 20.700 51.634 58.835 1.00166.31 N +ATOM 25782 CA ASN N 133 20.013 52.925 58.912 1.00146.53 C +ATOM 25783 C ASN N 133 18.512 52.762 58.757 1.00134.65 C +ATOM 25784 O ASN N 133 17.904 53.357 57.863 1.00121.98 O +ATOM 25785 CB ASN N 133 20.527 53.867 57.822 1.00137.13 C +ATOM 25786 CG ASN N 133 22.027 53.893 57.741 1.00163.92 C +ATOM 25787 OD1 ASN N 133 22.700 53.621 58.719 1.00176.62 O +ATOM 25788 ND2 ASN N 133 22.557 54.162 56.553 1.00160.93 N +ATOM 25789 N VAL N 134 17.947 51.898 59.597 1.00105.52 N +ATOM 25790 CA VAL N 134 16.530 51.604 59.574 1.00 92.44 C +ATOM 25791 C VAL N 134 15.821 52.872 60.029 1.00120.59 C +ATOM 25792 O VAL N 134 14.749 53.222 59.508 1.00180.18 O +ATOM 25793 CB VAL N 134 16.183 50.416 60.496 1.00 86.47 C +ATOM 25794 CG1 VAL N 134 14.708 50.071 60.432 1.00 84.25 C +ATOM 25795 CG2 VAL N 134 17.007 49.193 60.120 1.00 95.78 C +ATOM 25796 N LYS N 135 16.455 53.596 60.949 1.00116.33 N +ATOM 25797 CA LYS N 135 16.090 54.991 61.197 1.00118.04 C +ATOM 25798 C LYS N 135 17.326 55.873 61.320 1.00128.32 C +ATOM 25799 O LYS N 135 18.434 55.406 61.618 1.00168.14 O +ATOM 25800 CB LYS N 135 15.259 55.102 62.468 1.00118.26 C +ATOM 25801 CG LYS N 135 13.938 54.360 62.395 1.00137.92 C +ATOM 25802 CD LYS N 135 13.222 54.415 63.732 1.00164.67 C +ATOM 25803 CE LYS N 135 11.901 53.675 63.696 1.00173.22 C +ATOM 25804 NZ LYS N 135 11.009 54.149 64.788 1.00147.41 N +ATOM 25805 N SER N 136 17.116 57.168 61.138 1.00131.51 N +ATOM 25806 CA SER N 136 18.194 58.139 61.258 1.00147.63 C +ATOM 25807 C SER N 136 17.642 59.546 61.404 1.00154.06 C +ATOM 25808 O SER N 136 16.516 59.830 60.987 1.00168.72 O +ATOM 25809 CB SER N 136 19.141 58.053 60.057 1.00149.30 C +ATOM 25810 OG SER N 136 19.280 59.310 59.410 1.00190.56 O +ATOM 25811 N GLY N 137 18.445 60.429 61.984 1.00150.61 N +ATOM 25812 CA GLY N 137 18.043 61.820 62.140 1.00159.90 C +ATOM 25813 C GLY N 137 19.177 62.731 62.557 1.00166.30 C +ATOM 25814 O GLY N 137 20.296 62.281 62.792 1.00148.20 O +ATOM 25815 N GLY N 138 18.897 64.030 62.593 1.00186.20 N +ATOM 25816 CA GLY N 138 19.906 65.011 62.964 1.00189.26 C +ATOM 25817 C GLY N 138 19.311 66.361 63.284 1.00206.49 C +ATOM 25818 O GLY N 138 18.317 66.774 62.681 1.00264.82 O +ATOM 25819 N VAL N 139 19.910 67.041 64.258 1.00201.23 N +ATOM 25820 CA VAL N 139 19.492 68.394 64.641 1.00167.45 C +ATOM 25821 C VAL N 139 20.706 69.271 64.915 1.00159.44 C +ATOM 25822 O VAL N 139 21.576 68.904 65.705 1.00166.83 O +ATOM 25823 CB VAL N 139 18.614 68.396 65.903 1.00130.47 C +ATOM 25824 CG1 VAL N 139 18.324 69.822 66.324 1.00115.71 C +ATOM 25825 CG2 VAL N 139 17.320 67.624 65.665 1.00142.96 C +ATOM 25826 N GLY N 140 20.772 70.410 64.228 1.00175.96 N +ATOM 25827 CA GLY N 140 21.915 71.307 64.332 1.00176.08 C +ATOM 25828 C GLY N 140 21.580 72.762 64.085 1.00176.17 C +ATOM 25829 O GLY N 140 20.732 73.090 63.249 1.00172.18 O +ATOM 25830 N ALA N 141 22.234 73.640 64.835 1.00179.67 N +ATOM 25831 CA ALA N 141 21.994 75.072 64.714 1.00165.80 C +ATOM 25832 C ALA N 141 23.273 75.869 64.916 1.00162.30 C +ATOM 25833 O ALA N 141 24.109 75.538 65.763 1.00187.29 O +ATOM 25834 CB ALA N 141 20.913 75.518 65.692 1.00141.83 C +ATOM 25835 N ARG N 142 23.440 76.891 64.093 1.00171.88 N +ATOM 25836 CA ARG N 142 24.540 77.812 64.261 1.00183.86 C +ATOM 25837 C ARG N 142 23.994 79.235 64.259 1.00198.72 C +ATOM 25838 O ARG N 142 23.018 79.537 63.571 1.00152.19 O +ATOM 25839 CB ARG N 142 25.595 77.629 63.165 1.00164.25 C +ATOM 25840 CG ARG N 142 26.810 78.522 63.364 1.00143.89 C +ATOM 25841 CD ARG N 142 28.094 77.795 63.068 1.00156.40 C +ATOM 25842 NE ARG N 142 28.262 77.701 61.625 1.00178.69 N +ATOM 25843 CZ ARG N 142 28.941 76.736 61.009 1.00194.69 C +ATOM 25844 NH1 ARG N 142 29.622 75.823 61.699 1.00192.80 N +ATOM 25845 NH2 ARG N 142 29.008 76.729 59.683 1.00199.57 N +ATOM 25846 N TYR N 143 24.605 80.087 65.080 1.00228.02 N +ATOM 25847 CA TYR N 143 24.105 81.442 65.325 1.00200.43 C +ATOM 25848 C TYR N 143 25.230 82.477 65.176 1.00177.44 C +ATOM 25849 O TYR N 143 25.853 82.900 66.151 1.00114.09 O +ATOM 25850 CB TYR N 143 23.468 81.525 66.726 1.00186.74 C +ATOM 25851 CG TYR N 143 22.819 82.844 66.994 1.00183.76 C +ATOM 25852 CD1 TYR N 143 21.671 83.215 66.311 1.00190.35 C +ATOM 25853 CD2 TYR N 143 23.414 83.769 67.834 1.00183.40 C +ATOM 25854 CE1 TYR N 143 21.113 84.468 66.483 1.00190.67 C +ATOM 25855 CE2 TYR N 143 22.861 85.022 68.024 1.00200.60 C +ATOM 25856 CZ TYR N 143 21.710 85.367 67.344 1.00197.97 C +ATOM 25857 OH TYR N 143 21.152 86.611 67.521 1.00205.03 O +ATOM 25858 N GLY N 145 27.913 82.795 65.053 1.00178.49 N +ATOM 25859 CA GLY N 145 29.293 82.365 65.273 1.00191.15 C +ATOM 25860 C GLY N 145 29.438 81.062 66.050 1.00201.00 C +ATOM 25861 O GLY N 145 30.435 80.364 65.894 1.00174.36 O +ATOM 25862 N ILE N 146 28.408 80.685 66.811 1.00210.33 N +ATOM 25863 CA ILE N 146 28.465 79.508 67.698 1.00176.03 C +ATOM 25864 C ILE N 146 27.480 78.439 67.204 1.00161.05 C +ATOM 25865 O ILE N 146 26.357 78.764 66.824 1.00208.21 O +ATOM 25866 CB ILE N 146 28.128 79.888 69.163 1.00152.73 C +ATOM 25867 CG1 ILE N 146 28.745 81.246 69.517 1.00146.23 C +ATOM 25868 CG2 ILE N 146 28.622 78.818 70.128 1.00150.79 C +ATOM 25869 CD1 ILE N 146 27.787 82.414 69.387 1.00137.29 C +ATOM 25870 N GLY N 147 27.888 77.171 67.206 1.00147.88 N +ATOM 25871 CA GLY N 147 27.025 76.113 66.679 1.00143.67 C +ATOM 25872 C GLY N 147 27.195 74.734 67.291 1.00147.29 C +ATOM 25873 O GLY N 147 28.242 74.398 67.837 1.00131.70 O +ATOM 25874 N ALA N 148 26.141 73.933 67.202 1.00165.48 N +ATOM 25875 CA ALA N 148 26.209 72.538 67.607 1.00166.03 C +ATOM 25876 C ALA N 148 25.295 71.692 66.733 1.00178.06 C +ATOM 25877 O ALA N 148 24.467 72.218 65.982 1.00148.12 O +ATOM 25878 CB ALA N 148 25.851 72.389 69.081 1.00132.25 C +ATOM 25879 N ASP N 149 25.474 70.378 66.813 1.00201.78 N +ATOM 25880 CA ASP N 149 24.612 69.453 66.097 1.00194.22 C +ATOM 25881 C ASP N 149 24.771 68.031 66.628 1.00166.01 C +ATOM 25882 O ASP N 149 25.849 67.645 67.089 1.00142.83 O +ATOM 25883 CB ASP N 149 24.894 69.506 64.591 1.00205.15 C +ATOM 25884 CG ASP N 149 26.098 68.703 64.200 1.00224.64 C +ATOM 25885 OD1 ASP N 149 27.223 69.166 64.468 1.00216.64 O +ATOM 25886 OD2 ASP N 149 25.916 67.613 63.626 1.00235.28 O +ATOM 25887 N THR N 150 23.686 67.267 66.596 1.00159.37 N +ATOM 25888 CA THR N 150 23.789 65.824 66.766 1.00162.64 C +ATOM 25889 C THR N 150 23.207 65.119 65.553 1.00158.59 C +ATOM 25890 O THR N 150 22.369 65.667 64.835 1.00123.15 O +ATOM 25891 CB THR N 150 23.078 65.312 68.040 1.00145.48 C +ATOM 25892 OG1 THR N 150 21.694 65.654 67.985 1.00147.48 O +ATOM 25893 CG2 THR N 150 23.701 65.897 69.282 1.00128.11 C +ATOM 25894 N GLN N 151 23.681 63.904 65.330 1.00149.97 N +ATOM 25895 CA GLN N 151 23.142 63.046 64.315 1.00156.35 C +ATOM 25896 C GLN N 151 23.058 61.647 64.878 1.00149.41 C +ATOM 25897 O GLN N 151 23.923 61.231 65.627 1.00134.28 O +ATOM 25898 CB GLN N 151 24.062 63.073 63.096 1.00185.23 C +ATOM 25899 CG GLN N 151 23.980 64.375 62.327 1.00182.53 C +ATOM 25900 CD GLN N 151 25.211 64.611 61.485 1.00186.36 C +ATOM 25901 OE1 GLN N 151 25.726 63.681 60.867 1.00164.21 O +ATOM 25902 NE2 GLN N 151 25.691 65.853 61.453 1.00188.25 N +ATOM 25903 N TYR N 152 22.032 60.900 64.495 1.00162.68 N +ATOM 25904 CA TYR N 152 21.933 59.515 64.924 1.00155.51 C +ATOM 25905 C TYR N 152 21.504 58.591 63.800 1.00150.52 C +ATOM 25906 O TYR N 152 20.721 58.981 62.938 1.00139.10 O +ATOM 25907 CB TYR N 152 20.995 59.406 66.125 1.00122.93 C +ATOM 25908 CG TYR N 152 19.623 58.819 65.855 1.00 82.97 C +ATOM 25909 CD1 TYR N 152 18.712 59.467 65.033 1.00 70.56 C +ATOM 25910 CD2 TYR N 152 19.204 57.692 66.538 1.00 80.81 C +ATOM 25911 CE1 TYR N 152 17.437 58.973 64.847 1.00 76.95 C +ATOM 25912 CE2 TYR N 152 17.915 57.220 66.413 1.00 86.25 C +ATOM 25913 CZ TYR N 152 17.037 57.861 65.563 1.00 88.98 C +ATOM 25914 OH TYR N 152 15.743 57.403 65.472 1.00101.60 O +ATOM 25915 N GLN N 153 22.007 57.366 63.841 1.00121.04 N +ATOM 25916 CA GLN N 153 21.451 56.327 63.013 1.00126.53 C +ATOM 25917 C GLN N 153 21.212 55.054 63.823 1.00104.97 C +ATOM 25918 O GLN N 153 21.893 54.819 64.821 1.00 81.68 O +ATOM 25919 CB GLN N 153 22.342 55.966 61.846 1.00132.57 C +ATOM 25920 CG GLN N 153 23.765 55.477 62.168 1.00138.23 C +ATOM 25921 CD GLN N 153 24.353 54.527 61.123 1.00108.07 C +ATOM 25922 OE1 GLN N 153 24.823 53.381 61.382 1.00 75.05 O +ATOM 25923 NE2 GLN N 153 24.356 55.018 59.927 1.00102.13 N +ATOM 25924 N LEU N 154 20.286 54.210 63.359 1.00 96.54 N +ATOM 25925 CA LEU N 154 20.144 52.891 63.946 1.00107.15 C +ATOM 25926 C LEU N 154 19.806 51.794 62.933 1.00104.02 C +ATOM 25927 O LEU N 154 19.037 52.011 61.978 1.00 87.17 O +ATOM 25928 CB LEU N 154 19.111 52.923 65.071 1.00102.88 C +ATOM 25929 CG LEU N 154 17.654 53.065 64.635 1.00130.45 C +ATOM 25930 CD1 LEU N 154 16.962 51.715 64.529 1.00126.62 C +ATOM 25931 CD2 LEU N 154 16.930 53.982 65.607 1.00178.77 C +ATOM 25932 N ASP N 155 20.308 50.594 63.247 1.00 92.45 N +ATOM 25933 CA ASP N 155 20.294 49.437 62.360 1.00 84.20 C +ATOM 25934 C ASP N 155 19.585 48.290 63.054 1.00 91.49 C +ATOM 25935 O ASP N 155 19.415 48.311 64.275 1.00 91.82 O +ATOM 25936 CB ASP N 155 21.724 49.023 62.045 1.00 88.20 C +ATOM 25937 CG ASP N 155 22.589 50.205 61.648 1.00 98.39 C +ATOM 25938 OD1 ASP N 155 23.073 50.926 62.553 1.00 94.06 O +ATOM 25939 OD2 ASP N 155 22.838 50.392 60.431 1.00 97.58 O +ATOM 25940 N GLN N 156 19.145 47.297 62.283 1.00 96.93 N +ATOM 25941 CA GLN N 156 18.436 46.147 62.860 1.00113.12 C +ATOM 25942 C GLN N 156 19.207 44.839 62.648 1.00112.49 C +ATOM 25943 O GLN N 156 20.032 44.741 61.759 1.00 97.74 O +ATOM 25944 CB GLN N 156 17.033 46.028 62.262 1.00121.52 C +ATOM 25945 CG GLN N 156 16.121 45.045 62.981 1.00115.13 C +ATOM 25946 CD GLN N 156 14.647 45.281 62.675 1.00102.03 C +ATOM 25947 OE1 GLN N 156 14.291 46.098 61.813 1.00 72.81 O +ATOM 25948 NE2 GLN N 156 13.781 44.566 63.387 1.00 99.30 N +ATOM 25949 N ILE N 157 18.958 43.862 63.515 1.00106.48 N +ATOM 25950 CA ILE N 157 19.577 42.552 63.396 1.00 89.77 C +ATOM 25951 C ILE N 157 18.619 41.530 63.996 1.00 84.67 C +ATOM 25952 O ILE N 157 17.962 41.799 65.020 1.00100.54 O +ATOM 25953 CB ILE N 157 20.948 42.519 64.101 1.00 77.40 C +ATOM 25954 CG1 ILE N 157 21.824 41.427 63.515 1.00 64.20 C +ATOM 25955 CG2 ILE N 157 20.773 42.312 65.607 1.00 78.70 C +ATOM 25956 CD1 ILE N 157 23.253 41.443 64.022 1.00 66.53 C +ATOM 25957 N ALA N 158 18.461 40.398 63.331 1.00 70.23 N +ATOM 25958 CA ALA N 158 17.509 39.421 63.814 1.00 75.34 C +ATOM 25959 C ALA N 158 18.130 38.068 63.801 1.00 79.13 C +ATOM 25960 O ALA N 158 19.021 37.780 63.000 1.00110.28 O +ATOM 25961 CB ALA N 158 16.216 39.445 63.001 1.00 74.02 C +ATOM 25962 N VAL N 159 17.667 37.223 64.711 1.00 85.13 N +ATOM 25963 CA VAL N 159 18.238 35.905 64.872 1.00114.68 C +ATOM 25964 C VAL N 159 17.137 34.868 65.029 1.00136.49 C +ATOM 25965 O VAL N 159 16.243 35.006 65.864 1.00194.54 O +ATOM 25966 CB VAL N 159 19.205 35.871 66.071 1.00103.83 C +ATOM 25967 CG1 VAL N 159 19.440 34.451 66.552 1.00100.98 C +ATOM 25968 CG2 VAL N 159 20.530 36.508 65.689 1.00125.00 C +ATOM 25969 N ASN N 160 17.230 33.805 64.236 1.00118.13 N +ATOM 25970 CA ASN N 160 16.421 32.617 64.438 1.00112.54 C +ATOM 25971 C ASN N 160 17.233 31.600 65.250 1.00 87.28 C +ATOM 25972 O ASN N 160 18.382 31.315 64.923 1.00 69.74 O +ATOM 25973 CB ASN N 160 16.017 32.043 63.079 1.00115.81 C +ATOM 25974 CG ASN N 160 15.204 30.751 63.181 1.00128.73 C +ATOM 25975 OD1 ASN N 160 15.577 29.799 63.876 1.00 97.69 O +ATOM 25976 ND2 ASN N 160 14.145 30.672 62.388 1.00136.54 N +ATOM 25977 N LEU N 161 16.628 31.072 66.320 1.00 79.42 N +ATOM 25978 CA LEU N 161 17.090 29.818 66.947 1.00 75.40 C +ATOM 25979 C LEU N 161 15.971 28.800 67.031 1.00 68.95 C +ATOM 25980 O LEU N 161 14.796 29.152 67.086 1.00 96.22 O +ATOM 25981 CB LEU N 161 17.579 30.071 68.347 1.00 65.88 C +ATOM 25982 CG LEU N 161 18.791 30.980 68.464 1.00 78.62 C +ATOM 25983 CD1 LEU N 161 19.042 31.315 69.921 1.00 72.06 C +ATOM 25984 CD2 LEU N 161 19.996 30.310 67.828 1.00 87.13 C +ATOM 25985 N ARG N 162 16.304 27.536 66.884 1.00 63.59 N +ATOM 25986 CA ARG N 162 15.254 26.528 66.843 1.00 69.03 C +ATOM 25987 C ARG N 162 15.711 25.157 67.310 1.00 84.20 C +ATOM 25988 O ARG N 162 16.758 24.648 66.886 1.00104.97 O +ATOM 25989 CB ARG N 162 14.585 26.443 65.454 1.00 74.28 C +ATOM 25990 CG ARG N 162 15.453 26.010 64.285 1.00 88.95 C +ATOM 25991 CD ARG N 162 14.578 25.567 63.124 1.00103.86 C +ATOM 25992 NE ARG N 162 15.331 24.954 62.032 1.00131.46 N +ATOM 25993 CZ ARG N 162 15.962 25.622 61.074 1.00133.58 C +ATOM 25994 NH1 ARG N 162 16.062 26.943 61.125 1.00107.14 N +ATOM 25995 NH2 ARG N 162 16.551 24.947 60.088 1.00169.67 N +ATOM 25996 N VAL N 163 14.915 24.575 68.203 1.00104.87 N +ATOM 25997 CA VAL N 163 15.187 23.261 68.786 1.00133.51 C +ATOM 25998 C VAL N 163 14.621 22.189 67.888 1.00126.11 C +ATOM 25999 O VAL N 163 13.414 22.155 67.665 1.00169.35 O +ATOM 26000 CB VAL N 163 14.511 23.078 70.163 1.00126.00 C +ATOM 26001 CG1 VAL N 163 14.802 21.672 70.700 1.00 98.63 C +ATOM 26002 CG2 VAL N 163 14.964 24.174 71.127 1.00131.13 C +ATOM 26003 N VAL N 164 15.492 21.277 67.459 1.00 82.90 N +ATOM 26004 CA VAL N 164 15.109 20.145 66.610 1.00 54.84 C +ATOM 26005 C VAL N 164 15.294 18.858 67.358 1.00 53.30 C +ATOM 26006 O VAL N 164 16.298 18.697 68.089 1.00 81.19 O +ATOM 26007 CB VAL N 164 15.980 20.059 65.381 1.00 51.47 C +ATOM 26008 CG1 VAL N 164 15.601 18.866 64.553 1.00 44.91 C +ATOM 26009 CG2 VAL N 164 15.856 21.329 64.580 1.00 59.76 C +ATOM 26010 N ASN N 165 14.293 17.994 67.267 1.00 46.55 N +ATOM 26011 CA ASN N 165 14.353 16.752 67.998 1.00 64.19 C +ATOM 26012 C ASN N 165 15.100 15.722 67.188 1.00 81.53 C +ATOM 26013 O ASN N 165 14.675 15.389 66.060 1.00111.12 O +ATOM 26014 CB ASN N 165 12.963 16.230 68.305 1.00 77.33 C +ATOM 26015 CG ASN N 165 13.002 15.011 69.222 1.00104.67 C +ATOM 26016 OD1 ASN N 165 14.051 14.651 69.760 1.00 64.57 O +ATOM 26017 ND2 ASN N 165 11.873 14.320 69.333 1.00133.30 N +ATOM 26018 N VAL N 166 16.196 15.203 67.745 1.00 82.95 N +ATOM 26019 CA VAL N 166 17.069 14.262 67.018 1.00112.67 C +ATOM 26020 C VAL N 166 16.325 12.987 66.670 1.00108.37 C +ATOM 26021 O VAL N 166 16.463 12.472 65.572 1.00 82.63 O +ATOM 26022 CB VAL N 166 18.313 13.889 67.849 1.00116.22 C +ATOM 26023 CG1 VAL N 166 18.888 12.524 67.448 1.00 83.12 C +ATOM 26024 CG2 VAL N 166 19.349 15.009 67.753 1.00137.30 C +ATOM 26025 N SER N 167 15.456 12.568 67.580 1.00109.01 N +ATOM 26026 CA SER N 167 14.776 11.300 67.451 1.00119.48 C +ATOM 26027 C SER N 167 13.696 11.300 66.362 1.00132.93 C +ATOM 26028 O SER N 167 13.231 10.236 65.966 1.00137.78 O +ATOM 26029 CB SER N 167 14.173 10.922 68.794 1.00152.05 C +ATOM 26030 OG SER N 167 15.109 11.144 69.843 1.00217.53 O +ATOM 26031 N THR N 168 13.325 12.481 65.851 1.00144.92 N +ATOM 26032 CA THR N 168 12.266 12.585 64.832 1.00119.07 C +ATOM 26033 C THR N 168 12.576 13.555 63.681 1.00 89.09 C +ATOM 26034 O THR N 168 12.103 13.388 62.557 1.00 75.19 O +ATOM 26035 CB THR N 168 10.930 13.004 65.480 1.00129.62 C +ATOM 26036 OG1 THR N 168 11.127 14.179 66.279 1.00116.80 O +ATOM 26037 CG2 THR N 168 10.380 11.870 66.357 1.00146.17 C +ATOM 26038 N GLY N 169 13.266 14.631 63.994 1.00 68.02 N +ATOM 26039 CA GLY N 169 13.377 15.694 63.045 1.00 80.38 C +ATOM 26040 C GLY N 169 12.298 16.748 63.204 1.00103.08 C +ATOM 26041 O GLY N 169 12.376 17.825 62.593 1.00110.51 O +ATOM 26042 N GLU N 170 11.292 16.470 64.032 1.00115.59 N +ATOM 26043 CA GLU N 170 10.316 17.501 64.416 1.00135.27 C +ATOM 26044 C GLU N 170 11.066 18.672 65.018 1.00133.83 C +ATOM 26045 O GLU N 170 11.904 18.497 65.879 1.00124.64 O +ATOM 26046 CB GLU N 170 9.301 16.977 65.452 1.00138.84 C +ATOM 26047 CG GLU N 170 8.200 16.096 64.870 1.00158.40 C +ATOM 26048 CD GLU N 170 7.781 14.941 65.767 1.00152.06 C +ATOM 26049 OE1 GLU N 170 8.472 14.680 66.770 1.00145.74 O +ATOM 26050 OE2 GLU N 170 6.787 14.253 65.434 1.00148.79 O +ATOM 26051 N ILE N 171 10.819 19.870 64.506 1.00122.83 N +ATOM 26052 CA ILE N 171 11.256 21.064 65.207 1.00120.84 C +ATOM 26053 C ILE N 171 10.386 21.252 66.448 1.00108.35 C +ATOM 26054 O ILE N 171 9.166 21.225 66.342 1.00159.65 O +ATOM 26055 CB ILE N 171 11.149 22.295 64.310 1.00116.49 C +ATOM 26056 CG1 ILE N 171 12.209 22.212 63.214 1.00112.64 C +ATOM 26057 CG2 ILE N 171 11.303 23.559 65.147 1.00127.21 C +ATOM 26058 CD1 ILE N 171 11.952 23.158 62.067 1.00111.93 C +ATOM 26059 N LEU N 172 11.005 21.354 67.618 1.00 99.25 N +ATOM 26060 CA LEU N 172 10.251 21.407 68.862 1.00 93.38 C +ATOM 26061 C LEU N 172 10.027 22.851 69.297 1.00110.83 C +ATOM 26062 O LEU N 172 9.197 23.139 70.200 1.00126.98 O +ATOM 26063 CB LEU N 172 10.937 20.626 69.994 1.00 77.08 C +ATOM 26064 CG LEU N 172 10.634 19.133 70.213 1.00 68.00 C +ATOM 26065 CD1 LEU N 172 10.201 18.545 68.894 1.00 70.94 C +ATOM 26066 CD2 LEU N 172 11.697 18.293 70.899 1.00 64.57 C +ATOM 26067 N SER N 173 10.736 23.765 68.645 1.00 89.71 N +ATOM 26068 CA SER N 173 10.562 25.170 68.935 1.00124.03 C +ATOM 26069 C SER N 173 11.300 26.007 67.904 1.00123.12 C +ATOM 26070 O SER N 173 12.483 25.824 67.692 1.00112.08 O +ATOM 26071 CB SER N 173 11.086 25.494 70.349 1.00156.70 C +ATOM 26072 OG SER N 173 11.260 26.897 70.537 1.00183.80 O +ATOM 26073 N SER N 174 10.638 27.042 67.392 1.00150.12 N +ATOM 26074 CA SER N 174 11.318 28.117 66.646 1.00143.75 C +ATOM 26075 C SER N 174 11.062 29.483 67.281 1.00147.14 C +ATOM 26076 O SER N 174 9.949 29.779 67.708 1.00142.83 O +ATOM 26077 CB SER N 174 10.834 28.151 65.197 1.00128.82 C +ATOM 26078 OG SER N 174 11.641 28.986 64.380 1.00117.58 O +ATOM 26079 N VAL N 175 12.116 30.290 67.386 1.00163.50 N +ATOM 26080 CA VAL N 175 12.012 31.631 67.967 1.00153.39 C +ATOM 26081 C VAL N 175 12.770 32.658 67.136 1.00156.66 C +ATOM 26082 O VAL N 175 13.847 32.366 66.595 1.00266.87 O +ATOM 26083 CB VAL N 175 12.531 31.679 69.428 1.00126.56 C +ATOM 26084 CG1 VAL N 175 11.689 30.788 70.313 1.00119.58 C +ATOM 26085 CG2 VAL N 175 13.978 31.241 69.516 1.00135.57 C +ATOM 26086 N ASN N 176 12.224 33.867 67.075 1.00117.87 N +ATOM 26087 CA ASN N 176 12.752 34.916 66.214 1.00124.83 C +ATOM 26088 C ASN N 176 13.023 36.194 66.990 1.00115.67 C +ATOM 26089 O ASN N 176 12.125 37.029 67.105 1.00179.55 O +ATOM 26090 CB ASN N 176 11.747 35.169 65.075 1.00141.61 C +ATOM 26091 CG ASN N 176 12.130 34.435 63.791 1.00153.24 C +ATOM 26092 OD1 ASN N 176 12.937 33.517 63.866 1.00150.06 O +ATOM 26093 ND2 ASN N 176 11.503 34.764 62.635 1.00153.51 N +ATOM 26094 N THR N 177 14.262 36.395 67.445 1.00 89.97 N +ATOM 26095 CA THR N 177 14.604 37.598 68.209 1.00 95.82 C +ATOM 26096 C THR N 177 15.212 38.701 67.339 1.00104.79 C +ATOM 26097 O THR N 177 15.673 38.447 66.230 1.00115.85 O +ATOM 26098 CB THR N 177 15.570 37.288 69.348 1.00 92.69 C +ATOM 26099 OG1 THR N 177 16.852 36.970 68.808 1.00119.76 O +ATOM 26100 CG2 THR N 177 15.066 36.115 70.176 1.00 97.91 C +ATOM 26101 N SER N 178 15.149 39.936 67.832 1.00110.72 N +ATOM 26102 CA SER N 178 15.599 41.106 67.074 1.00120.62 C +ATOM 26103 C SER N 178 16.211 42.151 67.999 1.00122.25 C +ATOM 26104 O SER N 178 15.851 42.254 69.174 1.00137.56 O +ATOM 26105 CB SER N 178 14.445 41.736 66.281 1.00103.83 C +ATOM 26106 OG SER N 178 14.804 43.032 65.800 1.00122.70 O +ATOM 26107 N LYS N 179 17.107 42.960 67.450 1.00100.53 N +ATOM 26108 CA LYS N 179 17.818 43.914 68.263 1.00 99.13 C +ATOM 26109 C LYS N 179 18.286 45.088 67.414 1.00101.25 C +ATOM 26110 O LYS N 179 18.661 44.939 66.249 1.00 86.79 O +ATOM 26111 CB LYS N 179 18.988 43.207 68.943 1.00111.75 C +ATOM 26112 CG LYS N 179 19.290 43.683 70.356 1.00112.05 C +ATOM 26113 CD LYS N 179 20.365 44.749 70.326 1.00130.58 C +ATOM 26114 CE LYS N 179 20.555 45.348 71.698 1.00127.18 C +ATOM 26115 NZ LYS N 179 21.369 46.588 71.632 1.00150.20 N +ATOM 26116 N THR N 180 18.288 46.264 68.026 1.00122.67 N +ATOM 26117 CA THR N 180 18.634 47.492 67.325 1.00144.11 C +ATOM 26118 C THR N 180 20.028 48.009 67.733 1.00154.55 C +ATOM 26119 O THR N 180 20.369 48.076 68.924 1.00111.22 O +ATOM 26120 CB THR N 180 17.566 48.592 67.533 1.00134.02 C +ATOM 26121 OG1 THR N 180 18.158 49.879 67.321 1.00152.54 O +ATOM 26122 CG2 THR N 180 16.966 48.511 68.928 1.00107.00 C +ATOM 26123 N ILE N 181 20.834 48.349 66.725 1.00155.17 N +ATOM 26124 CA ILE N 181 22.172 48.888 66.952 1.00149.66 C +ATOM 26125 C ILE N 181 22.156 50.415 66.844 1.00138.67 C +ATOM 26126 O ILE N 181 21.886 50.965 65.764 1.00142.60 O +ATOM 26127 CB ILE N 181 23.195 48.290 65.950 1.00134.52 C +ATOM 26128 CG1 ILE N 181 23.123 46.763 65.978 1.00130.36 C +ATOM 26129 CG2 ILE N 181 24.621 48.725 66.285 1.00139.73 C +ATOM 26130 CD1 ILE N 181 22.750 46.153 64.648 1.00123.89 C +ATOM 26131 N LEU N 182 22.462 51.086 67.959 1.00108.24 N +ATOM 26132 CA LEU N 182 22.478 52.552 68.016 1.00125.83 C +ATOM 26133 C LEU N 182 23.839 53.216 67.694 1.00137.40 C +ATOM 26134 O LEU N 182 24.893 52.776 68.161 1.00131.89 O +ATOM 26135 CB LEU N 182 22.033 53.007 69.397 1.00108.06 C +ATOM 26136 CG LEU N 182 21.980 54.527 69.608 1.00 99.32 C +ATOM 26137 CD1 LEU N 182 20.997 55.238 68.687 1.00 77.92 C +ATOM 26138 CD2 LEU N 182 21.653 54.775 71.071 1.00107.81 C +ATOM 26139 N SER N 183 23.784 54.321 66.949 1.00139.80 N +ATOM 26140 CA SER N 183 24.961 55.145 66.672 1.00137.73 C +ATOM 26141 C SER N 183 24.593 56.630 66.735 1.00142.24 C +ATOM 26142 O SER N 183 23.508 57.024 66.297 1.00120.71 O +ATOM 26143 CB SER N 183 25.527 54.816 65.285 1.00139.60 C +ATOM 26144 OG SER N 183 25.432 53.432 65.009 1.00114.80 O +ATOM 26145 N TYR N 184 25.486 57.448 67.289 1.00147.52 N +ATOM 26146 CA TYR N 184 25.267 58.892 67.329 1.00128.23 C +ATOM 26147 C TYR N 184 26.555 59.718 67.322 1.00131.30 C +ATOM 26148 O TYR N 184 27.617 59.277 67.787 1.00140.89 O +ATOM 26149 CB TYR N 184 24.361 59.285 68.508 1.00105.50 C +ATOM 26150 CG TYR N 184 24.891 58.892 69.860 1.00107.43 C +ATOM 26151 CD1 TYR N 184 25.765 59.720 70.557 1.00130.79 C +ATOM 26152 CD2 TYR N 184 24.496 57.707 70.464 1.00108.77 C +ATOM 26153 CE1 TYR N 184 26.243 59.363 71.807 1.00141.57 C +ATOM 26154 CE2 TYR N 184 24.967 57.344 71.720 1.00114.75 C +ATOM 26155 CZ TYR N 184 25.837 58.171 72.386 1.00125.29 C +ATOM 26156 OH TYR N 184 26.328 57.793 73.608 1.00114.03 O +ATOM 26157 N GLU N 185 26.418 60.949 66.837 1.00148.15 N +ATOM 26158 CA GLU N 185 27.523 61.896 66.707 1.00170.85 C +ATOM 26159 C GLU N 185 27.125 63.271 67.223 1.00162.51 C +ATOM 26160 O GLU N 185 26.296 63.948 66.628 1.00139.54 O +ATOM 26161 CB GLU N 185 27.996 62.049 65.259 1.00181.07 C +ATOM 26162 CG GLU N 185 28.082 60.771 64.454 1.00179.53 C +ATOM 26163 CD GLU N 185 28.750 61.014 63.115 1.00174.09 C +ATOM 26164 OE1 GLU N 185 29.097 62.185 62.815 1.00162.55 O +ATOM 26165 OE2 GLU N 185 28.956 60.034 62.376 1.00175.93 O +ATOM 26166 N VAL N 186 27.754 63.681 68.319 1.00167.52 N +ATOM 26167 CA VAL N 186 27.548 64.999 68.901 1.00144.77 C +ATOM 26168 C VAL N 186 28.726 65.912 68.551 1.00132.59 C +ATOM 26169 O VAL N 186 29.874 65.474 68.572 1.00121.22 O +ATOM 26170 CB VAL N 186 27.390 64.900 70.431 1.00129.24 C +ATOM 26171 CG1 VAL N 186 26.979 66.245 71.002 1.00138.88 C +ATOM 26172 CG2 VAL N 186 26.374 63.824 70.805 1.00118.00 C +ATOM 26173 N GLN N 187 28.429 67.166 68.216 1.00135.29 N +ATOM 26174 CA GLN N 187 29.455 68.098 67.770 1.00140.60 C +ATOM 26175 C GLN N 187 29.112 69.521 68.150 1.00136.52 C +ATOM 26176 O GLN N 187 27.971 69.950 68.005 1.00141.50 O +ATOM 26177 CB GLN N 187 29.604 68.023 66.247 1.00148.89 C +ATOM 26178 CG GLN N 187 30.537 66.943 65.731 1.00165.04 C +ATOM 26179 CD GLN N 187 30.269 66.607 64.276 1.00210.38 C +ATOM 26180 OE1 GLN N 187 29.973 67.493 63.470 1.00251.34 O +ATOM 26181 NE2 GLN N 187 30.343 65.317 63.933 1.00230.82 N +ATOM 26182 N ALA N 188 30.117 70.261 68.602 1.00156.87 N +ATOM 26183 CA ALA N 188 29.938 71.677 68.915 1.00167.88 C +ATOM 26184 C ALA N 188 31.165 72.482 68.501 1.00173.06 C +ATOM 26185 O ALA N 188 32.287 72.017 68.648 1.00161.11 O +ATOM 26186 CB ALA N 188 29.649 71.855 70.398 1.00147.85 C +ATOM 26187 N GLY N 189 30.943 73.675 67.959 1.00188.69 N +ATOM 26188 CA GLY N 189 32.037 74.523 67.507 1.00198.42 C +ATOM 26189 C GLY N 189 31.771 76.002 67.716 1.00216.60 C +ATOM 26190 O GLY N 189 30.657 76.481 67.502 1.00238.50 O +ATOM 26191 N VAL N 190 32.795 76.727 68.151 1.00221.96 N +ATOM 26192 CA VAL N 190 32.694 78.171 68.332 1.00208.36 C +ATOM 26193 C VAL N 190 33.610 78.867 67.326 1.00220.42 C +ATOM 26194 O VAL N 190 34.763 78.455 67.136 1.00218.83 O +ATOM 26195 CB VAL N 190 33.062 78.581 69.774 1.00189.03 C +ATOM 26196 CG1 VAL N 190 32.714 80.038 70.014 1.00172.48 C +ATOM 26197 CG2 VAL N 190 32.359 77.682 70.789 1.00188.08 C +ATOM 26198 N PHE N 191 33.097 79.913 66.678 1.00213.28 N +ATOM 26199 CA PHE N 191 33.812 80.551 65.566 1.00195.14 C +ATOM 26200 C PHE N 191 33.820 82.075 65.691 1.00154.43 C +ATOM 26201 O PHE N 191 32.800 82.679 65.995 1.00 92.55 O +ATOM 26202 CB PHE N 191 33.162 80.143 64.242 1.00189.34 C +ATOM 26203 CG PHE N 191 34.054 80.298 63.044 1.00185.32 C +ATOM 26204 CD1 PHE N 191 34.339 81.556 62.531 1.00161.78 C +ATOM 26205 CD2 PHE N 191 34.564 79.181 62.395 1.00187.10 C +ATOM 26206 CE1 PHE N 191 35.142 81.698 61.415 1.00159.45 C +ATOM 26207 CE2 PHE N 191 35.375 79.317 61.283 1.00191.33 C +ATOM 26208 CZ PHE N 191 35.662 80.577 60.790 1.00186.48 C +ATOM 26209 N LEU N 200 39.339 83.314 65.930 1.00107.33 N +ATOM 26210 CA LEU N 200 39.075 82.266 66.917 1.00132.68 C +ATOM 26211 C LEU N 200 38.166 81.181 66.347 1.00171.92 C +ATOM 26212 O LEU N 200 36.995 81.440 66.059 1.00210.37 O +ATOM 26213 CB LEU N 200 38.415 82.855 68.169 1.00110.68 C +ATOM 26214 CG LEU N 200 37.893 81.807 69.169 1.00106.23 C +ATOM 26215 CD1 LEU N 200 38.875 81.661 70.323 1.00114.48 C +ATOM 26216 CD2 LEU N 200 36.486 82.104 69.669 1.00 85.45 C +ATOM 26217 N GLU N 201 38.700 79.965 66.223 1.00183.98 N +ATOM 26218 CA GLU N 201 37.876 78.767 66.078 1.00166.04 C +ATOM 26219 C GLU N 201 38.152 77.787 67.211 1.00161.25 C +ATOM 26220 O GLU N 201 39.273 77.715 67.713 1.00164.20 O +ATOM 26221 CB GLU N 201 38.138 78.091 64.736 1.00160.39 C +ATOM 26222 CG GLU N 201 37.019 77.154 64.323 1.00175.26 C +ATOM 26223 CD GLU N 201 37.275 76.476 62.986 1.00212.22 C +ATOM 26224 OE1 GLU N 201 37.573 77.182 61.996 1.00249.62 O +ATOM 26225 OE2 GLU N 201 37.122 75.238 62.907 1.00226.43 O +ATOM 26226 N GLY N 202 37.128 77.044 67.617 1.00146.62 N +ATOM 26227 CA GLY N 202 37.282 75.970 68.594 1.00151.59 C +ATOM 26228 C GLY N 202 36.207 74.909 68.433 1.00158.52 C +ATOM 26229 O GLY N 202 35.021 75.223 68.413 1.00157.84 O +ATOM 26230 N GLU N 203 36.617 73.647 68.302 1.00162.29 N +ATOM 26231 CA GLU N 203 35.673 72.560 68.036 1.00150.95 C +ATOM 26232 C GLU N 203 35.835 71.352 68.956 1.00130.60 C +ATOM 26233 O GLU N 203 36.950 70.909 69.231 1.00126.25 O +ATOM 26234 CB GLU N 203 35.793 72.104 66.585 1.00164.44 C +ATOM 26235 CG GLU N 203 35.343 73.165 65.579 1.00185.08 C +ATOM 26236 CD GLU N 203 35.339 72.693 64.128 1.00198.01 C +ATOM 26237 OE1 GLU N 203 35.854 71.585 63.857 1.00214.65 O +ATOM 26238 OE2 GLU N 203 34.854 73.454 63.254 1.00183.10 O +ATOM 26239 N VAL N 204 34.699 70.835 69.425 1.00114.05 N +ATOM 26240 CA VAL N 204 34.630 69.579 70.176 1.00 96.97 C +ATOM 26241 C VAL N 204 33.672 68.627 69.475 1.00 92.79 C +ATOM 26242 O VAL N 204 32.605 69.031 69.013 1.00106.26 O +ATOM 26243 CB VAL N 204 34.162 69.813 71.631 1.00 86.46 C +ATOM 26244 CG1 VAL N 204 33.724 68.516 72.307 1.00 74.21 C +ATOM 26245 CG2 VAL N 204 35.273 70.489 72.423 1.00 87.74 C +ATOM 26246 N GLY N 205 34.090 67.372 69.357 1.00114.62 N +ATOM 26247 CA GLY N 205 33.268 66.335 68.749 1.00126.41 C +ATOM 26248 C GLY N 205 33.326 65.018 69.514 1.00123.20 C +ATOM 26249 O GLY N 205 34.324 64.715 70.172 1.00102.39 O +ATOM 26250 N TYR N 206 32.239 64.255 69.451 1.00124.45 N +ATOM 26251 CA TYR N 206 32.180 62.928 70.067 1.00122.66 C +ATOM 26252 C TYR N 206 31.268 62.024 69.243 1.00142.14 C +ATOM 26253 O TYR N 206 30.229 62.465 68.768 1.00170.97 O +ATOM 26254 CB TYR N 206 31.657 63.014 71.513 1.00100.12 C +ATOM 26255 CG TYR N 206 31.502 61.682 72.199 1.00103.22 C +ATOM 26256 CD1 TYR N 206 32.626 60.984 72.675 1.00104.17 C +ATOM 26257 CD2 TYR N 206 30.250 61.092 72.344 1.00 87.38 C +ATOM 26258 CE1 TYR N 206 32.498 59.738 73.273 1.00 94.55 C +ATOM 26259 CE2 TYR N 206 30.115 59.843 72.928 1.00106.35 C +ATOM 26260 CZ TYR N 206 31.236 59.171 73.391 1.00107.24 C +ATOM 26261 OH TYR N 206 31.081 57.916 73.949 1.00125.78 O +ATOM 26262 N THR N 207 31.651 60.758 69.080 1.00138.19 N +ATOM 26263 CA THR N 207 30.824 59.789 68.352 1.00109.94 C +ATOM 26264 C THR N 207 30.794 58.444 69.071 1.00 82.34 C +ATOM 26265 O THR N 207 31.821 57.960 69.554 1.00 52.50 O +ATOM 26266 CB THR N 207 31.334 59.573 66.916 1.00126.85 C +ATOM 26267 OG1 THR N 207 32.666 59.052 66.958 1.00137.35 O +ATOM 26268 CG2 THR N 207 31.349 60.877 66.143 1.00132.15 C +ATOM 26269 N SER N 208 29.608 57.843 69.142 1.00 84.68 N +ATOM 26270 CA SER N 208 29.468 56.528 69.769 1.00 98.77 C +ATOM 26271 C SER N 208 28.650 55.529 68.918 1.00131.00 C +ATOM 26272 O SER N 208 27.516 55.804 68.547 1.00129.58 O +ATOM 26273 CB SER N 208 28.854 56.657 71.160 1.00 70.26 C +ATOM 26274 OG SER N 208 28.616 55.380 71.727 1.00 74.17 O +ATOM 26275 N ASN N 209 29.243 54.364 68.653 1.00138.53 N +ATOM 26276 CA ASN N 209 28.570 53.251 67.997 1.00108.62 C +ATOM 26277 C ASN N 209 28.415 52.092 68.963 1.00121.70 C +ATOM 26278 O ASN N 209 29.365 51.714 69.649 1.00 84.49 O +ATOM 26279 CB ASN N 209 29.379 52.756 66.802 1.00 94.31 C +ATOM 26280 CG ASN N 209 29.376 53.727 65.667 1.00103.76 C +ATOM 26281 OD1 ASN N 209 28.450 53.766 64.856 1.00105.45 O +ATOM 26282 ND2 ASN N 209 30.440 54.511 65.581 1.00124.34 N +ATOM 26283 N GLU N 210 27.245 51.463 68.939 1.00150.24 N +ATOM 26284 CA GLU N 210 27.090 50.153 69.565 1.00141.37 C +ATOM 26285 C GLU N 210 27.888 49.099 68.770 1.00160.45 C +ATOM 26286 O GLU N 210 27.945 49.150 67.540 1.00164.07 O +ATOM 26287 CB GLU N 210 25.616 49.760 69.616 1.00125.54 C +ATOM 26288 CG GLU N 210 25.156 49.197 70.944 1.00103.52 C +ATOM 26289 CD GLU N 210 23.637 49.225 71.075 1.00113.61 C +ATOM 26290 OE1 GLU N 210 22.941 50.076 70.432 1.00 80.30 O +ATOM 26291 OE2 GLU N 210 23.134 48.376 71.838 1.00109.35 O +ATOM 26292 N PRO N 211 28.549 48.167 69.473 1.00147.70 N +ATOM 26293 CA PRO N 211 29.170 47.050 68.775 1.00122.82 C +ATOM 26294 C PRO N 211 28.137 46.052 68.252 1.00 93.47 C +ATOM 26295 O PRO N 211 27.261 45.586 69.003 1.00 67.81 O +ATOM 26296 CB PRO N 211 30.045 46.403 69.860 1.00132.04 C +ATOM 26297 CG PRO N 211 30.200 47.426 70.925 1.00105.96 C +ATOM 26298 CD PRO N 211 28.897 48.170 70.903 1.00138.83 C +ATOM 26299 N VAL N 212 28.205 45.775 66.962 1.00 76.61 N +ATOM 26300 CA VAL N 212 27.257 44.856 66.334 1.00 93.47 C +ATOM 26301 C VAL N 212 27.483 43.497 66.965 1.00100.86 C +ATOM 26302 O VAL N 212 26.549 42.713 67.175 1.00 97.02 O +ATOM 26303 CB VAL N 212 27.480 44.780 64.789 1.00 94.40 C +ATOM 26304 CG1 VAL N 212 26.430 43.878 64.130 1.00 68.03 C +ATOM 26305 CG2 VAL N 212 27.470 46.179 64.153 1.00103.70 C +ATOM 26306 N MET N 213 28.773 43.193 67.126 1.00108.02 N +ATOM 26307 CA MET N 213 29.291 42.056 67.893 1.00 99.92 C +ATOM 26308 C MET N 213 28.466 41.780 69.172 1.00129.27 C +ATOM 26309 O MET N 213 27.993 40.659 69.430 1.00 93.97 O +ATOM 26310 CB MET N 213 30.706 42.477 68.229 1.00 80.17 C +ATOM 26311 CG MET N 213 31.540 41.503 68.985 1.00 92.58 C +ATOM 26312 SD MET N 213 33.139 42.316 69.208 1.00 96.33 S +ATOM 26313 CE MET N 213 32.977 42.534 70.999 1.00111.19 C +ATOM 26314 N LEU N 214 28.208 42.851 69.908 1.00142.28 N +ATOM 26315 CA LEU N 214 27.672 42.749 71.250 1.00121.67 C +ATOM 26316 C LEU N 214 26.151 42.635 71.178 1.00125.68 C +ATOM 26317 O LEU N 214 25.511 42.045 72.053 1.00145.75 O +ATOM 26318 CB LEU N 214 28.100 43.980 72.058 1.00125.68 C +ATOM 26319 CG LEU N 214 28.587 43.786 73.492 1.00122.74 C +ATOM 26320 CD1 LEU N 214 29.805 42.884 73.582 1.00 99.89 C +ATOM 26321 CD2 LEU N 214 28.884 45.151 74.109 1.00133.21 C +ATOM 26322 N CYS N 215 25.568 43.234 70.143 1.00119.39 N +ATOM 26323 CA CYS N 215 24.123 43.159 69.922 1.00128.91 C +ATOM 26324 C CYS N 215 23.725 41.748 69.496 1.00123.25 C +ATOM 26325 O CYS N 215 22.671 41.212 69.886 1.00104.14 O +ATOM 26326 CB CYS N 215 23.704 44.154 68.832 1.00111.64 C +ATOM 26327 SG CYS N 215 23.936 45.871 69.303 1.00133.76 S +ATOM 26328 N LEU N 216 24.542 41.184 68.614 1.00109.77 N +ATOM 26329 CA LEU N 216 24.339 39.823 68.190 1.00 83.92 C +ATOM 26330 C LEU N 216 24.314 38.955 69.431 1.00 79.39 C +ATOM 26331 O LEU N 216 23.450 38.087 69.583 1.00 65.81 O +ATOM 26332 CB LEU N 216 25.450 39.395 67.216 1.00 95.13 C +ATOM 26333 CG LEU N 216 25.389 37.937 66.728 1.00101.87 C +ATOM 26334 CD1 LEU N 216 24.063 37.610 66.063 1.00112.57 C +ATOM 26335 CD2 LEU N 216 26.532 37.636 65.772 1.00 97.70 C +ATOM 26336 N MET N 217 25.311 39.148 70.298 1.00 95.49 N +ATOM 26337 CA MET N 217 25.488 38.266 71.456 1.00120.27 C +ATOM 26338 C MET N 217 24.265 38.387 72.357 1.00130.13 C +ATOM 26339 O MET N 217 23.697 37.375 72.772 1.00140.49 O +ATOM 26340 CB MET N 217 26.781 38.600 72.222 1.00121.76 C +ATOM 26341 CG MET N 217 27.558 37.367 72.686 1.00106.65 C +ATOM 26342 SD MET N 217 26.699 36.455 73.978 1.00 99.72 S +ATOM 26343 CE MET N 217 27.668 34.958 74.105 1.00124.00 C +ATOM 26344 N SER N 218 23.832 39.627 72.587 1.00120.58 N +ATOM 26345 CA SER N 218 22.662 39.912 73.412 1.00 97.53 C +ATOM 26346 C SER N 218 21.425 39.191 72.882 1.00102.77 C +ATOM 26347 O SER N 218 20.717 38.499 73.630 1.00 91.88 O +ATOM 26348 CB SER N 218 22.404 41.417 73.442 1.00 81.19 C +ATOM 26349 OG SER N 218 21.422 41.727 74.415 1.00123.76 O +ATOM 26350 N ALA N 219 21.185 39.331 71.582 1.00112.67 N +ATOM 26351 CA ALA N 219 19.982 38.775 70.960 1.00111.47 C +ATOM 26352 C ALA N 219 19.964 37.236 70.992 1.00 92.54 C +ATOM 26353 O ALA N 219 18.921 36.605 71.184 1.00 57.03 O +ATOM 26354 CB ALA N 219 19.873 39.279 69.537 1.00115.30 C +ATOM 26355 N ILE N 220 21.140 36.636 70.890 1.00102.10 N +ATOM 26356 CA ILE N 220 21.247 35.181 70.983 1.00114.01 C +ATOM 26357 C ILE N 220 20.904 34.687 72.390 1.00112.63 C +ATOM 26358 O ILE N 220 20.217 33.676 72.554 1.00105.14 O +ATOM 26359 CB ILE N 220 22.655 34.689 70.559 1.00119.18 C +ATOM 26360 CG1 ILE N 220 22.847 34.916 69.047 1.00107.56 C +ATOM 26361 CG2 ILE N 220 22.847 33.213 70.915 1.00108.25 C +ATOM 26362 CD1 ILE N 220 24.282 34.849 68.580 1.00 91.77 C +ATOM 26363 N GLU N 221 21.382 35.404 73.407 1.00120.35 N +ATOM 26364 CA GLU N 221 21.064 35.073 74.814 1.00112.59 C +ATOM 26365 C GLU N 221 19.555 35.111 75.068 1.00 98.76 C +ATOM 26366 O GLU N 221 18.967 34.127 75.525 1.00 73.75 O +ATOM 26367 CB GLU N 221 21.758 36.056 75.756 1.00110.29 C +ATOM 26368 CG GLU N 221 23.254 35.833 75.894 1.00119.74 C +ATOM 26369 CD GLU N 221 23.997 37.028 76.485 1.00120.58 C +ATOM 26370 OE1 GLU N 221 23.645 38.201 76.185 1.00 68.50 O +ATOM 26371 OE2 GLU N 221 24.979 36.759 77.216 1.00154.45 O +ATOM 26372 N THR N 222 18.945 36.227 74.669 1.00 82.59 N +ATOM 26373 CA THR N 222 17.498 36.397 74.690 1.00 75.18 C +ATOM 26374 C THR N 222 16.770 35.220 74.039 1.00 89.57 C +ATOM 26375 O THR N 222 15.815 34.677 74.608 1.00 86.62 O +ATOM 26376 CB THR N 222 17.097 37.682 73.929 1.00 75.16 C +ATOM 26377 OG1 THR N 222 17.528 38.832 74.671 1.00 78.43 O +ATOM 26378 CG2 THR N 222 15.577 37.731 73.657 1.00 68.74 C +ATOM 26379 N GLY N 223 17.207 34.850 72.829 1.00 93.61 N +ATOM 26380 CA GLY N 223 16.662 33.689 72.124 1.00 92.62 C +ATOM 26381 C GLY N 223 16.747 32.398 72.938 1.00 93.64 C +ATOM 26382 O GLY N 223 15.797 31.594 72.947 1.00 83.10 O +ATOM 26383 N VAL N 224 17.862 32.213 73.644 1.00 75.19 N +ATOM 26384 CA VAL N 224 18.049 31.016 74.424 1.00 91.43 C +ATOM 26385 C VAL N 224 17.027 30.982 75.550 1.00119.13 C +ATOM 26386 O VAL N 224 16.438 29.932 75.842 1.00133.37 O +ATOM 26387 CB VAL N 224 19.464 30.931 75.007 1.00 98.48 C +ATOM 26388 CG1 VAL N 224 19.565 29.762 75.980 1.00111.98 C +ATOM 26389 CG2 VAL N 224 20.488 30.777 73.894 1.00104.44 C +ATOM 26390 N ILE N 225 16.800 32.133 76.174 1.00147.48 N +ATOM 26391 CA ILE N 225 15.808 32.219 77.251 1.00156.76 C +ATOM 26392 C ILE N 225 14.418 31.854 76.738 1.00153.97 C +ATOM 26393 O ILE N 225 13.773 30.973 77.307 1.00106.02 O +ATOM 26394 CB ILE N 225 15.768 33.616 77.901 1.00149.01 C +ATOM 26395 CG1 ILE N 225 17.066 33.879 78.666 1.00161.21 C +ATOM 26396 CG2 ILE N 225 14.596 33.718 78.862 1.00126.42 C +ATOM 26397 CD1 ILE N 225 17.308 35.341 78.970 1.00170.40 C +ATOM 26398 N PHE N 226 13.981 32.504 75.654 1.00155.56 N +ATOM 26399 CA PHE N 226 12.682 32.200 75.038 1.00150.26 C +ATOM 26400 C PHE N 226 12.551 30.709 74.682 1.00163.16 C +ATOM 26401 O PHE N 226 11.458 30.139 74.758 1.00191.53 O +ATOM 26402 CB PHE N 226 12.443 33.048 73.781 1.00137.71 C +ATOM 26403 CG PHE N 226 11.996 34.456 74.060 1.00109.13 C +ATOM 26404 CD1 PHE N 226 10.808 34.693 74.710 1.00133.71 C +ATOM 26405 CD2 PHE N 226 12.717 35.544 73.571 1.00 99.18 C +ATOM 26406 CE1 PHE N 226 10.379 35.995 74.933 1.00165.81 C +ATOM 26407 CE2 PHE N 226 12.270 36.842 73.740 1.00 97.20 C +ATOM 26408 CZ PHE N 226 11.113 37.071 74.445 1.00125.09 C +ATOM 26409 N LEU N 227 13.653 30.085 74.274 1.00128.94 N +ATOM 26410 CA LEU N 227 13.653 28.667 73.976 1.00120.13 C +ATOM 26411 C LEU N 227 13.400 27.845 75.234 1.00140.28 C +ATOM 26412 O LEU N 227 12.633 26.877 75.203 1.00152.22 O +ATOM 26413 CB LEU N 227 14.985 28.280 73.338 1.00113.24 C +ATOM 26414 CG LEU N 227 15.147 28.650 71.862 1.00117.11 C +ATOM 26415 CD1 LEU N 227 16.553 28.530 71.317 1.00109.75 C +ATOM 26416 CD2 LEU N 227 14.210 27.842 70.986 1.00140.13 C +ATOM 26417 N ILE N 228 14.079 28.193 76.326 1.00137.14 N +ATOM 26418 CA ILE N 228 13.953 27.434 77.570 1.00131.65 C +ATOM 26419 C ILE N 228 12.527 27.570 78.080 1.00127.77 C +ATOM 26420 O ILE N 228 11.892 26.586 78.465 1.00105.08 O +ATOM 26421 CB ILE N 228 14.938 27.909 78.663 1.00117.10 C +ATOM 26422 CG1 ILE N 228 16.381 27.650 78.241 1.00140.53 C +ATOM 26423 CG2 ILE N 228 14.685 27.166 79.962 1.00 92.10 C +ATOM 26424 CD1 ILE N 228 17.413 28.401 79.058 1.00161.49 C +ATOM 26425 N ASN N 229 12.037 28.802 78.102 1.00137.87 N +ATOM 26426 CA ASN N 229 10.698 29.082 78.610 1.00144.11 C +ATOM 26427 C ASN N 229 9.670 28.323 77.787 1.00135.62 C +ATOM 26428 O ASN N 229 8.735 27.729 78.328 1.00105.74 O +ATOM 26429 CB ASN N 229 10.429 30.592 78.568 1.00148.08 C +ATOM 26430 CG ASN N 229 9.235 30.997 79.393 1.00142.81 C +ATOM 26431 OD1 ASN N 229 8.856 30.314 80.356 1.00148.91 O +ATOM 26432 ND2 ASN N 229 8.672 32.155 79.072 1.00137.37 N +ATOM 26433 N ASP N 230 9.863 28.335 76.470 1.00148.32 N +ATOM 26434 CA ASP N 230 8.960 27.652 75.544 1.00155.09 C +ATOM 26435 C ASP N 230 8.978 26.153 75.803 1.00125.58 C +ATOM 26436 O ASP N 230 7.923 25.501 75.813 1.00125.88 O +ATOM 26437 CB ASP N 230 9.363 27.932 74.093 1.00172.05 C +ATOM 26438 CG ASP N 230 8.385 27.341 73.088 1.00190.33 C +ATOM 26439 OD1 ASP N 230 7.271 27.892 72.966 1.00258.49 O +ATOM 26440 OD2 ASP N 230 8.709 26.333 72.445 1.00144.53 O +ATOM 26441 N GLY N 231 10.165 25.627 76.072 1.00 99.82 N +ATOM 26442 CA GLY N 231 10.312 24.207 76.358 1.00128.62 C +ATOM 26443 C GLY N 231 9.702 23.801 77.691 1.00139.07 C +ATOM 26444 O GLY N 231 9.115 22.708 77.812 1.00137.06 O +ATOM 26445 N ILE N 232 9.756 24.714 78.662 1.00146.98 N +ATOM 26446 CA ILE N 232 9.073 24.518 79.949 1.00143.33 C +ATOM 26447 C ILE N 232 7.556 24.399 79.764 1.00156.25 C +ATOM 26448 O ILE N 232 6.951 23.435 80.234 1.00129.53 O +ATOM 26449 CB ILE N 232 9.376 25.666 80.934 1.00134.88 C +ATOM 26450 CG1 ILE N 232 10.819 25.552 81.424 1.00131.81 C +ATOM 26451 CG2 ILE N 232 8.403 25.650 82.112 1.00142.63 C +ATOM 26452 CD1 ILE N 232 11.355 26.822 82.048 1.00132.42 C +ATOM 26453 N ASP N 233 6.966 25.356 79.042 1.00182.26 N +ATOM 26454 CA ASP N 233 5.528 25.336 78.700 1.00154.88 C +ATOM 26455 C ASP N 233 5.117 24.050 77.978 1.00138.81 C +ATOM 26456 O ASP N 233 4.172 23.387 78.384 1.00169.69 O +ATOM 26457 CB ASP N 233 5.158 26.529 77.809 1.00152.98 C +ATOM 26458 CG ASP N 233 5.323 27.869 78.514 1.00169.89 C +ATOM 26459 OD1 ASP N 233 5.926 27.911 79.620 1.00167.60 O +ATOM 26460 OD2 ASP N 233 4.900 28.894 77.933 1.00141.68 O +ATOM 26461 N ARG N 234 5.875 23.664 76.954 1.00114.98 N +ATOM 26462 CA ARG N 234 5.519 22.510 76.124 1.00101.58 C +ATOM 26463 C ARG N 234 5.880 21.140 76.718 1.00122.59 C +ATOM 26464 O ARG N 234 5.639 20.105 76.099 1.00126.62 O +ATOM 26465 CB ARG N 234 6.144 22.673 74.746 1.00 90.28 C +ATOM 26466 CG ARG N 234 5.456 23.748 73.946 1.00 96.41 C +ATOM 26467 CD ARG N 234 6.321 24.296 72.829 1.00101.13 C +ATOM 26468 NE ARG N 234 5.607 25.367 72.153 1.00102.42 N +ATOM 26469 CZ ARG N 234 5.245 25.343 70.879 1.00108.77 C +ATOM 26470 NH1 ARG N 234 5.623 24.341 70.099 1.00126.01 N +ATOM 26471 NH2 ARG N 234 4.576 26.367 70.365 1.00109.78 N +ATOM 26472 N GLY N 235 6.517 21.136 77.886 1.00140.54 N +ATOM 26473 CA GLY N 235 6.883 19.892 78.558 1.00144.98 C +ATOM 26474 C GLY N 235 8.082 19.174 77.953 1.00156.11 C +ATOM 26475 O GLY N 235 8.139 17.941 77.974 1.00161.53 O +ATOM 26476 N LEU N 236 9.038 19.929 77.403 1.00155.78 N +ATOM 26477 CA LEU N 236 10.325 19.337 77.005 1.00153.83 C +ATOM 26478 C LEU N 236 11.134 19.037 78.263 1.00158.63 C +ATOM 26479 O LEU N 236 11.676 17.943 78.423 1.00148.08 O +ATOM 26480 CB LEU N 236 11.129 20.262 76.076 1.00137.30 C +ATOM 26481 CG LEU N 236 10.797 20.223 74.578 1.00120.76 C +ATOM 26482 CD1 LEU N 236 9.544 21.029 74.289 1.00140.75 C +ATOM 26483 CD2 LEU N 236 11.961 20.785 73.778 1.00130.63 C +ATOM 26484 N TRP N 237 11.208 20.020 79.154 1.00161.97 N +ATOM 26485 CA TRP N 237 11.991 19.893 80.383 1.00163.68 C +ATOM 26486 C TRP N 237 11.238 20.520 81.556 1.00173.15 C +ATOM 26487 O TRP N 237 10.289 21.285 81.352 1.00165.36 O +ATOM 26488 CB TRP N 237 13.372 20.532 80.198 1.00149.21 C +ATOM 26489 CG TRP N 237 13.349 21.718 79.283 1.00161.39 C +ATOM 26490 CD1 TRP N 237 12.754 22.916 79.518 1.00168.01 C +ATOM 26491 CD2 TRP N 237 13.932 21.809 77.975 1.00172.60 C +ATOM 26492 NE1 TRP N 237 12.931 23.752 78.445 1.00174.08 N +ATOM 26493 CE2 TRP N 237 13.668 23.102 77.491 1.00156.80 C +ATOM 26494 CE3 TRP N 237 14.658 20.924 77.170 1.00181.55 C +ATOM 26495 CZ2 TRP N 237 14.109 23.538 76.242 1.00137.44 C +ATOM 26496 CZ3 TRP N 237 15.091 21.362 75.921 1.00146.40 C +ATOM 26497 CH2 TRP N 237 14.799 22.650 75.468 1.00119.64 C +ATOM 26498 N ASP N 238 11.679 20.209 82.774 1.00187.39 N +ATOM 26499 CA ASP N 238 10.964 20.618 83.987 1.00181.28 C +ATOM 26500 C ASP N 238 11.855 21.307 85.025 1.00161.35 C +ATOM 26501 O ASP N 238 13.049 21.002 85.147 1.00135.98 O +ATOM 26502 CB ASP N 238 10.286 19.418 84.636 1.00172.90 C +ATOM 26503 CG ASP N 238 9.350 18.698 83.691 1.00178.29 C +ATOM 26504 OD1 ASP N 238 9.848 17.915 82.862 1.00176.48 O +ATOM 26505 OD2 ASP N 238 8.121 18.909 83.774 1.00183.77 O +ATOM 26506 N LEU N 239 11.257 22.240 85.768 1.00134.95 N +ATOM 26507 CA LEU N 239 11.971 23.008 86.779 1.00132.46 C +ATOM 26508 C LEU N 239 12.196 22.157 88.014 1.00136.15 C +ATOM 26509 O LEU N 239 11.354 21.334 88.381 1.00155.09 O +ATOM 26510 CB LEU N 239 11.187 24.269 87.165 1.00134.03 C +ATOM 26511 CG LEU N 239 11.194 25.477 86.229 1.00149.14 C +ATOM 26512 CD1 LEU N 239 10.453 26.650 86.852 1.00155.19 C +ATOM 26513 CD2 LEU N 239 12.614 25.889 85.899 1.00171.38 C +ATOM 26514 N GLN N 240 13.337 22.372 88.659 1.00143.90 N +ATOM 26515 CA GLN N 240 13.598 21.791 89.972 1.00158.81 C +ATOM 26516 C GLN N 240 12.472 22.156 90.943 1.00159.88 C +ATOM 26517 O GLN N 240 11.830 21.279 91.530 1.00120.04 O +ATOM 26518 CB GLN N 240 14.951 22.285 90.513 1.00164.93 C +ATOM 26519 CG GLN N 240 15.403 21.579 91.787 1.00171.31 C +ATOM 26520 CD GLN N 240 15.689 20.102 91.562 1.00167.70 C +ATOM 26521 OE1 GLN N 240 16.750 19.736 91.054 1.00156.70 O +ATOM 26522 NE2 GLN N 240 14.719 19.249 91.893 1.00163.44 N +ATOM 26523 N ASN N 241 12.250 23.458 91.093 1.00179.75 N +ATOM 26524 CA ASN N 241 11.207 23.988 91.964 1.00167.17 C +ATOM 26525 C ASN N 241 10.025 24.480 91.148 1.00162.21 C +ATOM 26526 O ASN N 241 10.114 25.517 90.475 1.00134.73 O +ATOM 26527 CB ASN N 241 11.757 25.149 92.789 1.00167.80 C +ATOM 26528 CG ASN N 241 12.111 24.741 94.199 1.00166.77 C +ATOM 26529 OD1 ASN N 241 11.353 25.013 95.128 1.00164.09 O +ATOM 26530 ND2 ASN N 241 13.247 24.062 94.367 1.00156.55 N +ATOM 26531 N LYS N 242 8.907 23.764 91.248 1.00153.33 N +ATOM 26532 CA LYS N 242 7.694 24.137 90.519 1.00140.30 C +ATOM 26533 C LYS N 242 7.171 25.475 91.035 1.00144.22 C +ATOM 26534 O LYS N 242 6.530 26.233 90.300 1.00100.89 O +ATOM 26535 CB LYS N 242 6.633 23.045 90.651 1.00134.51 C +ATOM 26536 CG LYS N 242 7.154 21.645 90.358 1.00148.30 C +ATOM 26537 CD LYS N 242 6.332 20.942 89.291 1.00174.08 C +ATOM 26538 CE LYS N 242 7.230 20.284 88.248 1.00188.71 C +ATOM 26539 NZ LYS N 242 6.467 19.454 87.275 1.00194.63 N +ATOM 26540 N ALA N 243 7.513 25.765 92.293 1.00174.98 N +ATOM 26541 CA ALA N 243 7.234 27.052 92.930 1.00187.24 C +ATOM 26542 C ALA N 243 7.930 28.204 92.216 1.00185.54 C +ATOM 26543 O ALA N 243 7.553 29.366 92.404 1.00188.07 O +ATOM 26544 CB ALA N 243 7.664 27.014 94.396 1.00205.01 C +ATOM 26545 N GLU N 244 8.970 27.896 91.439 1.00181.27 N +ATOM 26546 CA GLU N 244 9.736 28.944 90.774 1.00174.25 C +ATOM 26547 C GLU N 244 9.207 29.248 89.381 1.00150.40 C +ATOM 26548 O GLU N 244 9.877 29.928 88.620 1.00121.01 O +ATOM 26549 CB GLU N 244 11.225 28.581 90.718 1.00168.65 C +ATOM 26550 CG GLU N 244 11.939 28.699 92.055 1.00170.52 C +ATOM 26551 CD GLU N 244 13.448 28.596 91.930 1.00161.56 C +ATOM 26552 OE1 GLU N 244 13.963 27.469 91.755 1.00140.19 O +ATOM 26553 OE2 GLU N 244 14.123 29.647 92.013 1.00160.47 O +ATOM 26554 N ARG N 245 8.034 28.709 89.039 1.00140.33 N +ATOM 26555 CA ARG N 245 7.403 29.014 87.753 1.00137.65 C +ATOM 26556 C ARG N 245 7.167 30.511 87.563 1.00140.02 C +ATOM 26557 O ARG N 245 7.291 31.016 86.447 1.00 96.61 O +ATOM 26558 CB ARG N 245 6.080 28.288 87.583 1.00135.30 C +ATOM 26559 CG ARG N 245 5.480 28.452 86.184 1.00153.39 C +ATOM 26560 CD ARG N 245 4.188 27.638 85.985 1.00171.52 C +ATOM 26561 NE ARG N 245 4.446 26.365 85.307 1.00180.84 N +ATOM 26562 CZ ARG N 245 4.766 26.243 84.020 1.00171.61 C +ATOM 26563 NH1 ARG N 245 4.893 27.313 83.253 1.00158.94 N +ATOM 26564 NH2 ARG N 245 4.984 25.043 83.493 1.00169.89 N +ATOM 26565 N GLN N 246 6.833 31.215 88.645 1.00150.68 N +ATOM 26566 CA GLN N 246 6.517 32.644 88.554 1.00143.71 C +ATOM 26567 C GLN N 246 7.749 33.502 88.837 1.00127.25 C +ATOM 26568 O GLN N 246 7.626 34.673 89.179 1.00167.06 O +ATOM 26569 CB GLN N 246 5.375 33.024 89.507 1.00138.80 C +ATOM 26570 CG GLN N 246 4.010 32.498 89.105 1.00125.50 C +ATOM 26571 CD GLN N 246 3.863 31.016 89.390 1.00156.96 C +ATOM 26572 OE1 GLN N 246 4.235 30.536 90.471 1.00198.20 O +ATOM 26573 NE2 GLN N 246 3.299 30.282 88.436 1.00155.11 N +ATOM 26574 N ASN N 247 8.928 32.911 88.688 1.00104.55 N +ATOM 26575 CA ASN N 247 10.177 33.662 88.623 1.00133.30 C +ATOM 26576 C ASN N 247 10.046 34.970 87.826 1.00144.96 C +ATOM 26577 O ASN N 247 9.446 34.986 86.745 1.00176.61 O +ATOM 26578 CB ASN N 247 11.259 32.793 87.972 1.00148.23 C +ATOM 26579 CG ASN N 247 12.650 33.162 88.420 1.00148.70 C +ATOM 26580 OD1 ASN N 247 13.447 33.719 87.648 1.00139.45 O +ATOM 26581 ND2 ASN N 247 12.961 32.842 89.672 1.00131.04 N +ATOM 26582 N ASP N 248 10.645 36.049 88.335 1.00149.70 N +ATOM 26583 CA ASP N 248 10.556 37.378 87.695 1.00152.00 C +ATOM 26584 C ASP N 248 10.957 37.324 86.220 1.00166.85 C +ATOM 26585 O ASP N 248 10.289 37.896 85.345 1.00195.20 O +ATOM 26586 CB ASP N 248 11.465 38.393 88.409 1.00164.02 C +ATOM 26587 CG ASP N 248 10.949 38.792 89.782 1.00183.17 C +ATOM 26588 OD1 ASP N 248 9.723 38.929 89.953 1.00175.87 O +ATOM 26589 OD2 ASP N 248 11.784 38.969 90.693 1.00194.30 O +ATOM 26590 N ILE N 249 12.079 36.661 85.960 1.00171.92 N +ATOM 26591 CA ILE N 249 12.647 36.594 84.623 1.00162.43 C +ATOM 26592 C ILE N 249 11.715 35.789 83.712 1.00143.96 C +ATOM 26593 O ILE N 249 11.349 36.239 82.616 1.00146.50 O +ATOM 26594 CB ILE N 249 14.053 35.956 84.660 1.00162.49 C +ATOM 26595 CG1 ILE N 249 15.017 36.829 85.482 1.00150.41 C +ATOM 26596 CG2 ILE N 249 14.595 35.790 83.252 1.00178.11 C +ATOM 26597 CD1 ILE N 249 16.240 36.091 85.986 1.00145.03 C +ATOM 26598 N LEU N 250 11.311 34.612 84.185 1.00112.77 N +ATOM 26599 CA LEU N 250 10.455 33.721 83.398 1.00118.89 C +ATOM 26600 C LEU N 250 9.119 34.360 83.019 1.00144.25 C +ATOM 26601 O LEU N 250 8.617 34.149 81.915 1.00138.72 O +ATOM 26602 CB LEU N 250 10.207 32.414 84.150 1.00106.76 C +ATOM 26603 CG LEU N 250 11.347 31.391 84.077 1.00118.45 C +ATOM 26604 CD1 LEU N 250 11.170 30.254 85.070 1.00103.92 C +ATOM 26605 CD2 LEU N 250 11.452 30.833 82.667 1.00131.33 C +ATOM 26606 N VAL N 251 8.543 35.133 83.940 1.00182.02 N +ATOM 26607 CA VAL N 251 7.270 35.818 83.674 1.00172.02 C +ATOM 26608 C VAL N 251 7.467 37.055 82.798 1.00160.78 C +ATOM 26609 O VAL N 251 6.549 37.478 82.093 1.00173.22 O +ATOM 26610 CB VAL N 251 6.533 36.224 84.972 1.00156.39 C +ATOM 26611 CG1 VAL N 251 6.326 35.008 85.870 1.00146.95 C +ATOM 26612 CG2 VAL N 251 7.272 37.340 85.703 1.00154.39 C +ATOM 26613 N LYS N 252 8.670 37.620 82.833 1.00124.13 N +ATOM 26614 CA LYS N 252 9.008 38.734 81.955 1.00130.33 C +ATOM 26615 C LYS N 252 9.019 38.275 80.484 1.00159.19 C +ATOM 26616 O LYS N 252 8.449 38.926 79.604 1.00140.22 O +ATOM 26617 CB LYS N 252 10.358 39.321 82.380 1.00123.39 C +ATOM 26618 CG LYS N 252 10.868 40.487 81.540 1.00109.72 C +ATOM 26619 CD LYS N 252 12.219 40.958 82.064 1.00123.28 C +ATOM 26620 CE LYS N 252 13.221 41.142 80.938 1.00136.81 C +ATOM 26621 NZ LYS N 252 14.613 41.332 81.441 1.00166.44 N +ATOM 26622 N TYR N 253 9.674 37.145 80.231 1.00175.51 N +ATOM 26623 CA TYR N 253 9.792 36.610 78.871 1.00152.86 C +ATOM 26624 C TYR N 253 8.499 35.947 78.437 1.00131.51 C +ATOM 26625 O TYR N 253 8.157 35.945 77.251 1.00150.36 O +ATOM 26626 CB TYR N 253 10.980 35.636 78.768 1.00158.47 C +ATOM 26627 CG TYR N 253 12.319 36.363 78.819 1.00149.30 C +ATOM 26628 CD1 TYR N 253 12.870 36.931 77.674 1.00144.45 C +ATOM 26629 CD2 TYR N 253 12.988 36.556 80.024 1.00133.71 C +ATOM 26630 CE1 TYR N 253 14.064 37.630 77.733 1.00130.10 C +ATOM 26631 CE2 TYR N 253 14.185 37.259 80.082 1.00115.18 C +ATOM 26632 CZ TYR N 253 14.713 37.796 78.933 1.00109.14 C +ATOM 26633 OH TYR N 253 15.909 38.485 78.972 1.00 99.31 O +ATOM 26634 N ARG N 254 7.797 35.364 79.401 1.00147.85 N +ATOM 26635 CA ARG N 254 6.440 34.873 79.169 1.00166.04 C +ATOM 26636 C ARG N 254 5.547 36.016 78.682 1.00174.34 C +ATOM 26637 O ARG N 254 4.715 35.825 77.783 1.00173.98 O +ATOM 26638 CB ARG N 254 5.851 34.265 80.450 1.00152.34 C +ATOM 26639 CG ARG N 254 4.486 33.634 80.245 1.00140.21 C +ATOM 26640 CD ARG N 254 4.107 32.690 81.371 1.00149.75 C +ATOM 26641 NE ARG N 254 4.957 31.501 81.461 1.00141.57 N +ATOM 26642 CZ ARG N 254 5.853 31.266 82.419 1.00145.88 C +ATOM 26643 NH1 ARG N 254 6.077 32.154 83.376 1.00142.92 N +ATOM 26644 NH2 ARG N 254 6.540 30.131 82.407 1.00151.35 N +ATOM 26645 N HIS N 255 5.750 37.201 79.263 1.00182.49 N +ATOM 26646 CA HIS N 255 4.951 38.387 78.923 1.00182.88 C +ATOM 26647 C HIS N 255 5.272 38.926 77.547 1.00162.85 C +ATOM 26648 O HIS N 255 4.388 39.407 76.838 1.00124.33 O +ATOM 26649 CB HIS N 255 5.159 39.512 79.939 1.00191.61 C +ATOM 26650 CG HIS N 255 3.898 40.024 80.553 1.00214.87 C +ATOM 26651 ND1 HIS N 255 3.094 40.939 79.907 1.00222.83 N +ATOM 26652 CD2 HIS N 255 3.356 39.843 81.778 1.00207.92 C +ATOM 26653 CE1 HIS N 255 2.079 41.256 80.691 1.00198.21 C +ATOM 26654 NE2 HIS N 255 2.213 40.602 81.830 1.00198.74 N +ATOM 26655 N MET N 256 6.529 38.802 77.135 1.00167.12 N +ATOM 26656 CA MET N 256 6.910 39.242 75.787 1.00179.35 C +ATOM 26657 C MET N 256 6.277 38.369 74.670 1.00166.46 C +ATOM 26658 O MET N 256 6.074 38.846 73.552 1.00118.44 O +ATOM 26659 CB MET N 256 8.444 39.304 75.656 1.00181.00 C +ATOM 26660 CG MET N 256 9.119 40.116 76.757 1.00159.28 C +ATOM 26661 SD MET N 256 10.790 40.673 76.397 1.00165.70 S +ATOM 26662 CE MET N 256 10.470 41.880 75.107 1.00181.38 C +ATOM 26663 N SER N 257 5.931 37.120 74.998 1.00169.94 N +ATOM 26664 CA SER N 257 5.255 36.196 74.065 1.00147.50 C +ATOM 26665 C SER N 257 3.769 36.479 73.870 1.00112.99 C +ATOM 26666 O SER N 257 3.401 37.294 73.038 1.00118.51 O +ATOM 26667 CB SER N 257 5.395 34.754 74.559 1.00167.94 C +ATOM 26668 OG SER N 257 6.700 34.483 75.004 1.00171.45 O +TER 26669 SER N 257 +ATOM 26670 N LEU O 2 35.991 55.471 80.076 1.00114.75 N +ATOM 26671 CA LEU O 2 35.157 55.420 78.831 1.00123.13 C +ATOM 26672 C LEU O 2 36.054 55.253 77.582 1.00130.00 C +ATOM 26673 O LEU O 2 36.222 56.182 76.751 1.00 97.42 O +ATOM 26674 CB LEU O 2 34.251 56.658 78.715 1.00138.09 C +ATOM 26675 CG LEU O 2 33.185 56.914 79.808 1.00139.66 C +ATOM 26676 CD1 LEU O 2 32.436 58.209 79.497 1.00132.01 C +ATOM 26677 CD2 LEU O 2 32.193 55.764 80.014 1.00126.69 C +ATOM 26678 N THR O 3 36.731 54.102 77.565 1.00141.01 N +ATOM 26679 CA THR O 3 37.366 53.530 76.372 1.00139.22 C +ATOM 26680 C THR O 3 37.161 51.998 76.340 1.00119.08 C +ATOM 26681 O THR O 3 37.600 51.306 75.421 1.00117.32 O +ATOM 26682 CB THR O 3 38.886 53.826 76.317 1.00137.63 C +ATOM 26683 OG1 THR O 3 39.563 53.104 77.360 1.00123.09 O +ATOM 26684 CG2 THR O 3 39.163 55.337 76.414 1.00123.11 C +ATOM 26685 N ALA O 4 36.550 51.470 77.389 1.00115.31 N +ATOM 26686 CA ALA O 4 35.860 50.182 77.318 1.00107.56 C +ATOM 26687 C ALA O 4 34.555 50.376 76.511 1.00 86.67 C +ATOM 26688 O ALA O 4 34.328 51.439 75.949 1.00 64.04 O +ATOM 26689 CB ALA O 4 35.593 49.652 78.730 1.00114.98 C +ATOM 26690 N PRO O 5 33.699 49.355 76.427 1.00 88.41 N +ATOM 26691 CA PRO O 5 32.717 49.555 75.370 1.00108.24 C +ATOM 26692 C PRO O 5 31.540 50.425 75.809 1.00118.36 C +ATOM 26693 O PRO O 5 31.419 50.729 76.993 1.00166.35 O +ATOM 26694 CB PRO O 5 32.252 48.132 75.073 1.00154.35 C +ATOM 26695 CG PRO O 5 32.477 47.356 76.350 1.00135.39 C +ATOM 26696 CD PRO O 5 33.507 48.084 77.160 1.00 97.23 C +ATOM 26697 N PRO O 6 30.694 50.862 74.854 1.00121.66 N +ATOM 26698 CA PRO O 6 29.385 51.460 75.170 1.00114.86 C +ATOM 26699 C PRO O 6 28.351 50.413 75.530 1.00114.59 C +ATOM 26700 O PRO O 6 28.443 49.266 75.087 1.00102.32 O +ATOM 26701 CB PRO O 6 28.981 52.196 73.889 1.00106.20 C +ATOM 26702 CG PRO O 6 29.841 51.650 72.813 1.00113.48 C +ATOM 26703 CD PRO O 6 31.019 50.936 73.422 1.00128.66 C +ATOM 26704 N LYS O 7 27.383 50.796 76.355 1.00131.20 N +ATOM 26705 CA LYS O 7 26.432 49.826 76.894 1.00155.33 C +ATOM 26706 C LYS O 7 25.147 49.778 76.075 1.00137.41 C +ATOM 26707 O LYS O 7 24.925 50.624 75.192 1.00 86.23 O +ATOM 26708 CB LYS O 7 26.164 50.088 78.388 1.00159.98 C +ATOM 26709 CG LYS O 7 27.383 49.624 79.253 1.00155.50 C +ATOM 26710 CD LYS O 7 27.487 48.092 79.330 1.00168.85 C +ATOM 26711 CE LYS O 7 28.922 47.642 79.586 1.00164.55 C +ATOM 26712 NZ LYS O 7 28.989 46.331 80.294 1.00180.06 N +ATOM 26713 N GLU O 8 24.318 48.774 76.376 1.00132.00 N +ATOM 26714 CA GLU O 8 23.161 48.434 75.553 1.00134.93 C +ATOM 26715 C GLU O 8 22.105 49.521 75.460 1.00129.64 C +ATOM 26716 O GLU O 8 21.511 49.912 76.464 1.00126.92 O +ATOM 26717 CB GLU O 8 22.464 47.212 76.104 1.00122.34 C +ATOM 26718 CG GLU O 8 22.235 46.057 75.190 1.00129.49 C +ATOM 26719 CD GLU O 8 21.457 44.948 75.889 1.00153.24 C +ATOM 26720 OE1 GLU O 8 21.872 44.474 76.972 1.00132.85 O +ATOM 26721 OE2 GLU O 8 20.477 44.450 75.329 1.00216.98 O +ATOM 26722 N ALA O 9 21.893 50.002 74.240 1.00124.01 N +ATOM 26723 CA ALA O 9 20.800 50.895 73.920 1.00106.70 C +ATOM 26724 C ALA O 9 19.657 50.083 73.290 1.00116.64 C +ATOM 26725 O ALA O 9 19.768 49.596 72.158 1.00142.41 O +ATOM 26726 CB ALA O 9 21.280 51.978 72.964 1.00 86.94 C +ATOM 26727 N ALA O 10 18.559 49.974 74.030 1.00100.50 N +ATOM 26728 CA ALA O 10 17.395 49.142 73.679 1.00105.26 C +ATOM 26729 C ALA O 10 17.612 47.701 74.098 1.00103.63 C +ATOM 26730 O ALA O 10 18.740 47.277 74.340 1.00 99.16 O +ATOM 26731 CB ALA O 10 17.045 49.214 72.197 1.00105.97 C +ATOM 26732 N ARG O 11 16.506 46.972 74.243 1.00115.31 N +ATOM 26733 CA ARG O 11 16.534 45.569 74.679 1.00136.07 C +ATOM 26734 C ARG O 11 16.300 44.660 73.482 1.00128.63 C +ATOM 26735 O ARG O 11 15.618 45.050 72.548 1.00130.66 O +ATOM 26736 CB ARG O 11 15.444 45.289 75.736 1.00152.66 C +ATOM 26737 CG ARG O 11 14.016 45.409 75.225 1.00155.76 C +ATOM 26738 CD ARG O 11 13.051 45.765 76.352 1.00166.24 C +ATOM 26739 NE ARG O 11 12.526 47.124 76.220 1.00198.70 N +ATOM 26740 CZ ARG O 11 11.622 47.657 77.041 1.00192.18 C +ATOM 26741 NH1 ARG O 11 11.120 46.936 78.033 1.00193.74 N +ATOM 26742 NH2 ARG O 11 11.205 48.905 76.864 1.00169.89 N +ATOM 26743 N PRO O 12 16.832 43.428 73.519 1.00109.59 N +ATOM 26744 CA PRO O 12 16.393 42.454 72.538 1.00 94.73 C +ATOM 26745 C PRO O 12 14.929 42.121 72.779 1.00 94.21 C +ATOM 26746 O PRO O 12 14.572 41.579 73.833 1.00112.51 O +ATOM 26747 CB PRO O 12 17.289 41.230 72.802 1.00 77.30 C +ATOM 26748 CG PRO O 12 18.384 41.712 73.667 1.00 90.31 C +ATOM 26749 CD PRO O 12 17.810 42.859 74.453 1.00101.19 C +ATOM 26750 N THR O 13 14.081 42.505 71.838 1.00 76.27 N +ATOM 26751 CA THR O 13 12.713 42.009 71.809 1.00 91.19 C +ATOM 26752 C THR O 13 12.617 40.772 70.922 1.00 92.50 C +ATOM 26753 O THR O 13 13.492 40.558 70.070 1.00150.53 O +ATOM 26754 CB THR O 13 11.782 43.096 71.264 1.00 95.21 C +ATOM 26755 OG1 THR O 13 10.420 42.675 71.436 1.00 95.80 O +ATOM 26756 CG2 THR O 13 12.086 43.415 69.761 1.00 84.29 C +ATOM 26757 N LEU O 14 11.564 39.976 71.055 1.00 71.26 N +ATOM 26758 CA LEU O 14 11.344 38.974 70.018 1.00 70.54 C +ATOM 26759 C LEU O 14 10.800 39.662 68.756 1.00 63.23 C +ATOM 26760 O LEU O 14 10.365 40.783 68.805 1.00 53.32 O +ATOM 26761 CB LEU O 14 10.506 37.785 70.495 1.00 77.16 C +ATOM 26762 CG LEU O 14 9.169 38.055 71.130 1.00 93.60 C +ATOM 26763 CD1 LEU O 14 8.182 36.936 70.815 1.00 94.01 C +ATOM 26764 CD2 LEU O 14 9.362 38.167 72.621 1.00100.87 C +ATOM 26765 N MET O 15 10.959 39.045 67.596 1.00 88.22 N +ATOM 26766 CA MET O 15 11.026 39.801 66.327 1.00110.61 C +ATOM 26767 C MET O 15 9.670 40.423 65.965 1.00109.61 C +ATOM 26768 O MET O 15 8.670 39.712 65.860 1.00 85.90 O +ATOM 26769 CB MET O 15 11.549 38.914 65.162 1.00138.40 C +ATOM 26770 CG MET O 15 12.305 39.687 64.076 1.00144.24 C +ATOM 26771 SD MET O 15 12.258 39.135 62.342 1.00121.25 S +ATOM 26772 CE MET O 15 10.713 38.220 62.212 1.00137.84 C +ATOM 26773 N PRO O 16 9.654 41.749 65.731 1.00114.65 N +ATOM 26774 CA PRO O 16 8.436 42.549 65.568 1.00122.16 C +ATOM 26775 C PRO O 16 7.637 42.212 64.312 1.00112.90 C +ATOM 26776 O PRO O 16 7.717 42.906 63.309 1.00 81.39 O +ATOM 26777 CB PRO O 16 8.966 43.989 65.508 1.00121.43 C +ATOM 26778 CG PRO O 16 10.375 43.850 65.066 1.00114.92 C +ATOM 26779 CD PRO O 16 10.860 42.592 65.714 1.00112.82 C +ATOM 26780 N ARG O 17 6.831 41.160 64.403 1.00127.29 N +ATOM 26781 CA ARG O 17 5.878 40.812 63.349 1.00126.51 C +ATOM 26782 C ARG O 17 4.552 41.538 63.580 1.00124.24 C +ATOM 26783 O ARG O 17 4.185 41.783 64.717 1.00116.42 O +ATOM 26784 CB ARG O 17 5.651 39.300 63.343 1.00138.37 C +ATOM 26785 CG ARG O 17 6.668 38.538 62.515 1.00166.03 C +ATOM 26786 CD ARG O 17 6.713 37.051 62.836 1.00171.23 C +ATOM 26787 NE ARG O 17 7.452 36.776 64.065 1.00173.36 N +ATOM 26788 CZ ARG O 17 7.543 35.573 64.622 1.00200.38 C +ATOM 26789 NH1 ARG O 17 6.958 34.533 64.037 1.00219.79 N +ATOM 26790 NH2 ARG O 17 8.226 35.407 65.748 1.00185.55 N +ATOM 26791 N ALA O 18 3.854 41.917 62.512 1.00146.98 N +ATOM 26792 CA ALA O 18 2.621 42.716 62.645 1.00138.23 C +ATOM 26793 C ALA O 18 1.361 41.960 62.206 1.00132.04 C +ATOM 26794 O ALA O 18 1.023 40.931 62.792 1.00 79.94 O +ATOM 26795 CB ALA O 18 2.747 44.048 61.904 1.00138.84 C +ATOM 26796 N GLN O 19 0.671 42.470 61.184 1.00150.10 N +ATOM 26797 CA GLN O 19 -0.723 42.088 60.942 1.00163.23 C +ATOM 26798 C GLN O 19 -0.842 40.651 60.439 1.00149.08 C +ATOM 26799 O GLN O 19 -1.649 39.852 60.938 1.00104.56 O +ATOM 26800 CB GLN O 19 -1.367 43.049 59.934 1.00169.22 C +ATOM 26801 CG GLN O 19 -2.860 42.828 59.729 1.00178.92 C +ATOM 26802 CD GLN O 19 -3.639 42.864 61.034 1.00192.41 C +ATOM 26803 OE1 GLN O 19 -3.743 43.907 61.680 1.00203.80 O +ATOM 26804 NE2 GLN O 19 -4.190 41.720 61.427 1.00199.26 N +ATOM 26805 N SER O 20 -0.052 40.358 59.412 1.00143.70 N +ATOM 26806 CA SER O 20 0.061 39.023 58.863 1.00128.38 C +ATOM 26807 C SER O 20 0.161 37.987 59.983 1.00120.66 C +ATOM 26808 O SER O 20 -0.571 36.990 59.985 1.00 95.29 O +ATOM 26809 CB SER O 20 1.298 38.962 57.959 1.00140.82 C +ATOM 26810 OG SER O 20 1.287 40.018 57.003 1.00123.82 O +ATOM 26811 N TYR O 21 1.072 38.231 60.923 1.00130.31 N +ATOM 26812 CA TYR O 21 1.256 37.361 62.090 1.00164.17 C +ATOM 26813 C TYR O 21 -0.025 37.169 62.910 1.00149.84 C +ATOM 26814 O TYR O 21 -0.409 36.038 63.235 1.00131.01 O +ATOM 26815 CB TYR O 21 2.341 37.927 63.003 1.00174.90 C +ATOM 26816 CG TYR O 21 2.614 37.063 64.209 1.00165.05 C +ATOM 26817 CD1 TYR O 21 3.351 35.897 64.086 1.00175.12 C +ATOM 26818 CD2 TYR O 21 2.114 37.395 65.469 1.00130.80 C +ATOM 26819 CE1 TYR O 21 3.605 35.103 65.185 1.00183.84 C +ATOM 26820 CE2 TYR O 21 2.374 36.609 66.575 1.00109.39 C +ATOM 26821 CZ TYR O 21 3.119 35.469 66.427 1.00121.70 C +ATOM 26822 OH TYR O 21 3.422 34.658 67.492 1.00120.25 O +ATOM 26823 N LYS O 22 -0.676 38.277 63.239 1.00134.49 N +ATOM 26824 CA LYS O 22 -1.885 38.233 64.035 1.00150.45 C +ATOM 26825 C LYS O 22 -2.970 37.391 63.374 1.00144.01 C +ATOM 26826 O LYS O 22 -3.724 36.681 64.052 1.00128.97 O +ATOM 26827 CB LYS O 22 -2.396 39.656 64.289 1.00186.81 C +ATOM 26828 CG LYS O 22 -1.799 40.300 65.528 1.00209.84 C +ATOM 26829 CD LYS O 22 -2.554 39.846 66.785 1.00199.04 C +ATOM 26830 CE LYS O 22 -3.518 40.946 67.253 1.00181.03 C +ATOM 26831 NZ LYS O 22 -2.786 42.159 67.703 1.00170.88 N +ATOM 26832 N ASP O 23 -3.116 37.556 62.062 1.00141.72 N +ATOM 26833 CA ASP O 23 -4.073 36.762 61.290 1.00133.22 C +ATOM 26834 C ASP O 23 -3.673 35.299 61.349 1.00114.30 C +ATOM 26835 O ASP O 23 -4.519 34.415 61.514 1.00113.03 O +ATOM 26836 CB ASP O 23 -4.116 37.241 59.828 1.00124.68 C +ATOM 26837 CG ASP O 23 -4.729 38.604 59.688 1.00123.52 C +ATOM 26838 OD1 ASP O 23 -5.744 38.861 60.372 1.00136.80 O +ATOM 26839 OD2 ASP O 23 -4.208 39.422 58.895 1.00115.16 O +ATOM 26840 N LEU O 24 -2.382 35.057 61.151 1.00105.02 N +ATOM 26841 CA LEU O 24 -1.850 33.703 60.992 1.00147.70 C +ATOM 26842 C LEU O 24 -2.010 32.891 62.278 1.00149.12 C +ATOM 26843 O LEU O 24 -2.250 31.667 62.231 1.00141.18 O +ATOM 26844 CB LEU O 24 -0.366 33.771 60.598 1.00166.13 C +ATOM 26845 CG LEU O 24 0.396 32.450 60.400 1.00151.64 C +ATOM 26846 CD1 LEU O 24 0.222 31.926 58.981 1.00143.44 C +ATOM 26847 CD2 LEU O 24 1.870 32.645 60.723 1.00141.19 C +ATOM 26848 N THR O 25 -1.883 33.574 63.418 1.00152.31 N +ATOM 26849 CA THR O 25 -1.957 32.915 64.729 1.00163.90 C +ATOM 26850 C THR O 25 -3.397 32.573 65.124 1.00184.14 C +ATOM 26851 O THR O 25 -3.687 31.436 65.526 1.00137.69 O +ATOM 26852 CB THR O 25 -1.331 33.785 65.836 1.00132.20 C +ATOM 26853 OG1 THR O 25 -1.795 35.132 65.705 1.00102.20 O +ATOM 26854 CG2 THR O 25 0.176 33.758 65.733 1.00120.25 C +ATOM 26855 N HIS O 26 -4.297 33.540 64.935 1.00194.89 N +ATOM 26856 CA HIS O 26 -5.708 33.383 65.287 1.00168.18 C +ATOM 26857 C HIS O 26 -6.505 32.712 64.150 1.00133.69 C +ATOM 26858 O HIS O 26 -7.667 33.009 63.934 1.00138.01 O +ATOM 26859 CB HIS O 26 -6.311 34.750 65.650 1.00167.76 C +ATOM 26860 CG HIS O 26 -5.686 35.384 66.862 1.00163.93 C +ATOM 26861 ND1 HIS O 26 -4.397 35.876 66.864 1.00172.96 N +ATOM 26862 CD2 HIS O 26 -6.165 35.586 68.115 1.00144.19 C +ATOM 26863 CE1 HIS O 26 -4.113 36.362 68.061 1.00154.71 C +ATOM 26864 NE2 HIS O 26 -5.162 36.183 68.843 1.00126.85 N +ATOM 26865 N LEU O 27 -5.892 31.752 63.471 1.00138.10 N +ATOM 26866 CA LEU O 27 -6.600 30.939 62.487 1.00128.77 C +ATOM 26867 C LEU O 27 -7.234 29.710 63.144 1.00117.60 C +ATOM 26868 O LEU O 27 -6.611 29.047 63.978 1.00 93.72 O +ATOM 26869 CB LEU O 27 -5.647 30.471 61.388 1.00156.75 C +ATOM 26870 CG LEU O 27 -5.467 31.441 60.221 1.00169.59 C +ATOM 26871 CD1 LEU O 27 -4.278 31.037 59.363 1.00173.67 C +ATOM 26872 CD2 LEU O 27 -6.731 31.520 59.379 1.00169.10 C +ATOM 26873 N PRO O 28 -8.476 29.391 62.754 1.00107.33 N +ATOM 26874 CA PRO O 28 -9.215 28.280 63.372 1.00109.94 C +ATOM 26875 C PRO O 28 -8.506 26.976 63.109 1.00 96.31 C +ATOM 26876 O PRO O 28 -8.180 26.704 61.975 1.00 91.66 O +ATOM 26877 CB PRO O 28 -10.574 28.317 62.651 1.00119.21 C +ATOM 26878 CG PRO O 28 -10.315 29.060 61.378 1.00103.16 C +ATOM 26879 CD PRO O 28 -9.272 30.075 61.718 1.00103.96 C +ATOM 26880 N ALA O 29 -8.291 26.174 64.146 1.00118.03 N +ATOM 26881 CA ALA O 29 -7.415 25.008 64.044 1.00111.96 C +ATOM 26882 C ALA O 29 -8.046 23.857 63.224 1.00116.71 C +ATOM 26883 O ALA O 29 -9.269 23.687 63.198 1.00101.42 O +ATOM 26884 CB ALA O 29 -7.001 24.529 65.431 1.00 94.85 C +ATOM 26885 N PRO O 30 -7.205 23.097 62.499 1.00125.37 N +ATOM 26886 CA PRO O 30 -7.635 21.917 61.740 1.00124.27 C +ATOM 26887 C PRO O 30 -7.889 20.703 62.645 1.00107.62 C +ATOM 26888 O PRO O 30 -7.622 20.776 63.851 1.00 67.31 O +ATOM 26889 CB PRO O 30 -6.432 21.631 60.850 1.00129.00 C +ATOM 26890 CG PRO O 30 -5.261 22.107 61.637 1.00122.51 C +ATOM 26891 CD PRO O 30 -5.741 23.276 62.449 1.00131.90 C +ATOM 26892 N THR O 31 -8.368 19.600 62.058 1.00 96.52 N +ATOM 26893 CA THR O 31 -8.683 18.380 62.829 1.00110.73 C +ATOM 26894 C THR O 31 -7.437 17.711 63.399 1.00113.56 C +ATOM 26895 O THR O 31 -7.496 17.039 64.420 1.00132.07 O +ATOM 26896 CB THR O 31 -9.487 17.334 62.010 1.00114.05 C +ATOM 26897 OG1 THR O 31 -8.831 17.048 60.776 1.00110.45 O +ATOM 26898 CG2 THR O 31 -10.900 17.837 61.718 1.00135.95 C +ATOM 26899 N GLY O 32 -6.310 17.908 62.732 1.00134.12 N +ATOM 26900 CA GLY O 32 -5.004 17.555 63.283 1.00143.72 C +ATOM 26901 C GLY O 32 -3.944 18.380 62.577 1.00146.11 C +ATOM 26902 O GLY O 32 -4.175 18.851 61.462 1.00127.07 O +ATOM 26903 N LYS O 33 -2.801 18.599 63.221 1.00137.39 N +ATOM 26904 CA LYS O 33 -1.730 19.335 62.562 1.00128.20 C +ATOM 26905 C LYS O 33 -1.159 18.500 61.414 1.00153.13 C +ATOM 26906 O LYS O 33 -1.187 17.272 61.465 1.00134.59 O +ATOM 26907 CB LYS O 33 -0.633 19.738 63.541 1.00111.02 C +ATOM 26908 CG LYS O 33 -0.845 21.099 64.181 1.00108.16 C +ATOM 26909 CD LYS O 33 0.182 21.340 65.273 1.00138.38 C +ATOM 26910 CE LYS O 33 -0.348 22.308 66.315 1.00144.96 C +ATOM 26911 NZ LYS O 33 0.574 22.424 67.477 1.00180.45 N +ATOM 26912 N ILE O 34 -0.664 19.171 60.375 1.00167.29 N +ATOM 26913 CA ILE O 34 -0.143 18.489 59.201 1.00144.10 C +ATOM 26914 C ILE O 34 1.394 18.566 59.238 1.00153.65 C +ATOM 26915 O ILE O 34 1.981 19.533 59.742 1.00187.39 O +ATOM 26916 CB ILE O 34 -0.767 19.064 57.904 1.00145.26 C +ATOM 26917 CG1 ILE O 34 -2.266 18.759 57.862 1.00145.51 C +ATOM 26918 CG2 ILE O 34 -0.140 18.469 56.650 1.00180.95 C +ATOM 26919 CD1 ILE O 34 -3.126 19.999 57.850 1.00176.92 C +ATOM 26920 N PHE O 35 2.025 17.469 58.838 1.00124.71 N +ATOM 26921 CA PHE O 35 3.468 17.356 58.819 1.00 98.26 C +ATOM 26922 C PHE O 35 3.994 18.007 57.550 1.00 89.37 C +ATOM 26923 O PHE O 35 3.652 17.566 56.445 1.00110.79 O +ATOM 26924 CB PHE O 35 3.848 15.876 58.821 1.00107.48 C +ATOM 26925 CG PHE O 35 3.915 15.255 60.190 1.00 85.93 C +ATOM 26926 CD1 PHE O 35 4.585 15.884 61.225 1.00 81.72 C +ATOM 26927 CD2 PHE O 35 3.415 13.980 60.394 1.00 84.28 C +ATOM 26928 CE1 PHE O 35 4.677 15.294 62.467 1.00 79.35 C +ATOM 26929 CE2 PHE O 35 3.525 13.373 61.623 1.00 88.21 C +ATOM 26930 CZ PHE O 35 4.144 14.037 62.668 1.00 91.12 C +ATOM 26931 N VAL O 36 4.936 18.932 57.690 1.00 67.07 N +ATOM 26932 CA VAL O 36 5.466 19.611 56.521 1.00 80.59 C +ATOM 26933 C VAL O 36 7.006 19.636 56.472 1.00115.40 C +ATOM 26934 O VAL O 36 7.676 19.650 57.497 1.00151.14 O +ATOM 26935 CB VAL O 36 4.915 21.035 56.464 1.00 75.44 C +ATOM 26936 CG1 VAL O 36 5.606 21.911 57.496 1.00 94.03 C +ATOM 26937 CG2 VAL O 36 5.079 21.603 55.074 1.00 67.36 C +ATOM 26938 N SER O 37 7.556 19.688 55.263 1.00121.66 N +ATOM 26939 CA SER O 37 8.998 19.769 55.080 1.00104.86 C +ATOM 26940 C SER O 37 9.333 21.008 54.283 1.00112.93 C +ATOM 26941 O SER O 37 8.720 21.286 53.253 1.00 87.01 O +ATOM 26942 CB SER O 37 9.471 18.577 54.289 1.00111.33 C +ATOM 26943 OG SER O 37 9.471 17.405 55.064 1.00145.59 O +ATOM 26944 N VAL O 38 10.313 21.770 54.738 1.00105.71 N +ATOM 26945 CA VAL O 38 10.847 22.833 53.888 1.00131.92 C +ATOM 26946 C VAL O 38 12.334 22.581 53.697 1.00137.08 C +ATOM 26947 O VAL O 38 13.093 22.628 54.679 1.00220.41 O +ATOM 26948 CB VAL O 38 10.657 24.253 54.489 1.00140.17 C +ATOM 26949 CG1 VAL O 38 11.298 25.303 53.585 1.00123.34 C +ATOM 26950 CG2 VAL O 38 9.190 24.578 54.704 1.00141.73 C +ATOM 26951 N TYR O 39 12.748 22.396 52.440 1.00 90.85 N +ATOM 26952 CA TYR O 39 14.140 22.154 52.114 1.00 71.99 C +ATOM 26953 C TYR O 39 14.857 23.495 51.869 1.00 72.87 C +ATOM 26954 O TYR O 39 15.905 23.776 52.473 1.00102.07 O +ATOM 26955 CB TYR O 39 14.246 21.196 50.915 1.00 64.80 C +ATOM 26956 CG TYR O 39 14.159 19.724 51.307 1.00 64.17 C +ATOM 26957 CD1 TYR O 39 12.952 19.120 51.605 1.00 59.12 C +ATOM 26958 CD2 TYR O 39 15.304 18.931 51.379 1.00 86.99 C +ATOM 26959 CE1 TYR O 39 12.889 17.788 52.027 1.00 66.59 C +ATOM 26960 CE2 TYR O 39 15.250 17.582 51.779 1.00100.59 C +ATOM 26961 CZ TYR O 39 14.040 17.010 52.128 1.00 71.66 C +ATOM 26962 OH TYR O 39 14.002 15.661 52.489 1.00 37.40 O +ATOM 26963 N ASN O 40 14.307 24.337 51.004 1.00 73.45 N +ATOM 26964 CA ASN O 40 14.964 25.601 50.669 1.00 77.81 C +ATOM 26965 C ASN O 40 14.090 26.558 49.880 1.00 83.54 C +ATOM 26966 O ASN O 40 13.493 26.185 48.863 1.00 97.96 O +ATOM 26967 CB ASN O 40 16.242 25.341 49.861 1.00 95.21 C +ATOM 26968 CG ASN O 40 17.181 26.532 49.865 1.00106.63 C +ATOM 26969 OD1 ASN O 40 17.465 27.121 48.822 1.00130.68 O +ATOM 26970 ND2 ASN O 40 17.684 26.881 51.043 1.00119.61 N +ATOM 26971 N ILE O 41 14.072 27.816 50.304 1.00 80.32 N +ATOM 26972 CA ILE O 41 13.488 28.901 49.503 1.00 92.15 C +ATOM 26973 C ILE O 41 14.573 29.918 49.112 1.00 81.89 C +ATOM 26974 O ILE O 41 15.169 30.553 49.985 1.00 73.96 O +ATOM 26975 CB ILE O 41 12.347 29.620 50.265 1.00 87.95 C +ATOM 26976 CG1 ILE O 41 11.051 28.822 50.206 1.00 94.11 C +ATOM 26977 CG2 ILE O 41 12.056 30.959 49.621 1.00 88.07 C +ATOM 26978 CD1 ILE O 41 11.040 27.532 51.013 1.00 93.66 C +ATOM 26979 N GLN O 42 14.838 30.055 47.813 1.00 83.72 N +ATOM 26980 CA GLN O 42 16.016 30.802 47.337 1.00 94.36 C +ATOM 26981 C GLN O 42 15.734 32.271 47.088 1.00 87.59 C +ATOM 26982 O GLN O 42 14.586 32.675 46.903 1.00 75.35 O +ATOM 26983 CB GLN O 42 16.545 30.228 46.029 1.00121.01 C +ATOM 26984 CG GLN O 42 17.089 28.818 46.132 1.00142.88 C +ATOM 26985 CD GLN O 42 16.327 27.837 45.256 1.00164.97 C +ATOM 26986 OE1 GLN O 42 16.642 27.673 44.070 1.00203.77 O +ATOM 26987 NE2 GLN O 42 15.286 27.221 45.816 1.00140.37 N +ATOM 26988 N ASP O 43 16.802 33.063 47.106 1.00 83.31 N +ATOM 26989 CA ASP O 43 16.741 34.484 46.751 1.00 74.91 C +ATOM 26990 C ASP O 43 16.815 34.623 45.266 1.00 56.27 C +ATOM 26991 O ASP O 43 17.814 35.124 44.728 1.00 39.49 O +ATOM 26992 CB ASP O 43 17.905 35.250 47.404 1.00 97.01 C +ATOM 26993 CG ASP O 43 17.789 36.764 47.216 1.00124.05 C +ATOM 26994 OD1 ASP O 43 16.700 37.324 47.496 1.00168.07 O +ATOM 26995 OD2 ASP O 43 18.767 37.416 46.811 1.00112.63 O +ATOM 26996 N GLU O 44 15.783 34.111 44.593 1.00 57.40 N +ATOM 26997 CA GLU O 44 15.752 34.084 43.124 1.00 75.49 C +ATOM 26998 C GLU O 44 15.627 35.523 42.513 1.00 78.71 C +ATOM 26999 O GLU O 44 15.357 35.668 41.298 1.00 58.12 O +ATOM 27000 CB GLU O 44 14.626 33.146 42.598 1.00 69.41 C +ATOM 27001 CG GLU O 44 15.024 31.671 42.424 1.00 88.31 C +ATOM 27002 CD GLU O 44 13.879 30.755 41.946 1.00108.01 C +ATOM 27003 OE1 GLU O 44 13.133 31.098 40.998 1.00139.97 O +ATOM 27004 OE2 GLU O 44 13.743 29.638 42.478 1.00111.82 O +ATOM 27005 N THR O 45 15.930 36.547 43.330 1.00 77.33 N +ATOM 27006 CA THR O 45 15.627 37.945 42.997 1.00 69.20 C +ATOM 27007 C THR O 45 16.636 38.588 42.064 1.00 74.60 C +ATOM 27008 O THR O 45 16.242 39.236 41.095 1.00 85.09 O +ATOM 27009 CB THR O 45 15.449 38.829 44.241 1.00 48.92 C +ATOM 27010 OG1 THR O 45 14.861 40.064 43.839 1.00 76.04 O +ATOM 27011 CG2 THR O 45 16.735 39.101 44.916 1.00 43.41 C +ATOM 27012 N GLY O 46 17.905 38.276 42.256 1.00 91.32 N +ATOM 27013 CA GLY O 46 18.937 38.628 41.264 1.00120.05 C +ATOM 27014 C GLY O 46 19.487 40.013 41.533 1.00118.59 C +ATOM 27015 O GLY O 46 20.115 40.675 40.691 1.00131.30 O +ATOM 27016 N GLN O 47 19.310 40.456 42.747 1.00102.16 N +ATOM 27017 CA GLN O 47 19.475 41.827 42.961 1.00109.26 C +ATOM 27018 C GLN O 47 20.378 42.116 44.148 1.00132.55 C +ATOM 27019 O GLN O 47 20.302 41.474 45.207 1.00148.32 O +ATOM 27020 CB GLN O 47 18.111 42.430 43.127 1.00 97.90 C +ATOM 27021 CG GLN O 47 17.307 42.413 41.845 1.00 80.20 C +ATOM 27022 CD GLN O 47 18.068 42.987 40.680 1.00 89.08 C +ATOM 27023 OE1 GLN O 47 18.291 44.191 40.589 1.00 66.32 O +ATOM 27024 NE2 GLN O 47 18.453 42.135 39.765 1.00125.71 N +ATOM 27025 N PHE O 48 21.207 43.136 43.962 1.00133.99 N +ATOM 27026 CA PHE O 48 22.110 43.602 44.992 1.00108.11 C +ATOM 27027 C PHE O 48 21.894 45.080 45.268 1.00115.77 C +ATOM 27028 O PHE O 48 21.289 45.821 44.478 1.00103.05 O +ATOM 27029 CB PHE O 48 23.562 43.351 44.556 1.00117.10 C +ATOM 27030 CG PHE O 48 23.897 41.910 44.436 1.00103.10 C +ATOM 27031 CD1 PHE O 48 23.449 41.186 43.354 1.00 87.84 C +ATOM 27032 CD2 PHE O 48 24.547 41.268 45.455 1.00 94.69 C +ATOM 27033 CE1 PHE O 48 23.631 39.842 43.295 1.00 86.19 C +ATOM 27034 CE2 PHE O 48 24.729 39.918 45.411 1.00 96.45 C +ATOM 27035 CZ PHE O 48 24.302 39.209 44.315 1.00 99.10 C +ATOM 27036 N LYS O 49 22.495 45.528 46.363 1.00145.66 N +ATOM 27037 CA LYS O 49 22.388 46.920 46.779 1.00127.00 C +ATOM 27038 C LYS O 49 23.296 47.786 45.923 1.00114.33 C +ATOM 27039 O LYS O 49 24.384 47.354 45.509 1.00100.46 O +ATOM 27040 CB LYS O 49 22.715 47.074 48.275 1.00114.52 C +ATOM 27041 CG LYS O 49 21.695 46.360 49.159 1.00113.31 C +ATOM 27042 CD LYS O 49 21.800 46.588 50.660 1.00107.21 C +ATOM 27043 CE LYS O 49 20.605 45.886 51.320 1.00 99.07 C +ATOM 27044 NZ LYS O 49 20.541 45.984 52.811 1.00 85.35 N +ATOM 27045 N PRO O 50 22.839 49.009 45.645 1.00111.42 N +ATOM 27046 CA PRO O 50 23.606 49.939 44.839 1.00106.75 C +ATOM 27047 C PRO O 50 24.722 50.596 45.636 1.00106.07 C +ATOM 27048 O PRO O 50 24.753 50.531 46.893 1.00119.97 O +ATOM 27049 CB PRO O 50 22.558 50.970 44.406 1.00118.59 C +ATOM 27050 CG PRO O 50 21.534 50.945 45.496 1.00123.81 C +ATOM 27051 CD PRO O 50 21.507 49.534 46.009 1.00111.58 C +ATOM 27052 N TYR O 51 25.628 51.241 44.913 1.00109.75 N +ATOM 27053 CA TYR O 51 26.609 52.092 45.549 1.00114.88 C +ATOM 27054 C TYR O 51 25.919 53.021 46.565 1.00117.10 C +ATOM 27055 O TYR O 51 24.880 53.606 46.263 1.00101.63 O +ATOM 27056 CB TYR O 51 27.364 52.924 44.505 1.00 91.09 C +ATOM 27057 CG TYR O 51 28.613 53.522 45.075 1.00109.79 C +ATOM 27058 CD1 TYR O 51 29.788 52.786 45.107 1.00137.96 C +ATOM 27059 CD2 TYR O 51 28.626 54.803 45.641 1.00122.62 C +ATOM 27060 CE1 TYR O 51 30.949 53.293 45.671 1.00142.96 C +ATOM 27061 CE2 TYR O 51 29.811 55.349 46.165 1.00119.17 C +ATOM 27062 CZ TYR O 51 30.959 54.563 46.201 1.00132.49 C +ATOM 27063 OH TYR O 51 32.145 55.009 46.731 1.00121.57 O +ATOM 27064 N PRO O 52 26.496 53.171 47.775 1.00126.05 N +ATOM 27065 CA PRO O 52 27.816 52.701 48.233 1.00116.98 C +ATOM 27066 C PRO O 52 27.879 51.345 48.933 1.00 82.18 C +ATOM 27067 O PRO O 52 28.853 51.089 49.642 1.00 78.46 O +ATOM 27068 CB PRO O 52 28.235 53.804 49.215 1.00122.05 C +ATOM 27069 CG PRO O 52 26.940 54.239 49.831 1.00125.38 C +ATOM 27070 CD PRO O 52 25.898 54.118 48.741 1.00125.85 C +ATOM 27071 N ALA O 53 26.833 50.529 48.829 1.00 62.39 N +ATOM 27072 CA ALA O 53 26.858 49.219 49.488 1.00 70.52 C +ATOM 27073 C ALA O 53 28.006 48.407 48.932 1.00 71.28 C +ATOM 27074 O ALA O 53 28.509 48.685 47.807 1.00 67.42 O +ATOM 27075 CB ALA O 53 25.542 48.472 49.295 1.00 84.87 C +ATOM 27076 N SER O 54 28.361 47.343 49.645 1.00 66.66 N +ATOM 27077 CA SER O 54 29.253 46.384 49.040 1.00 88.55 C +ATOM 27078 C SER O 54 28.597 45.807 47.779 1.00 91.23 C +ATOM 27079 O SER O 54 27.395 45.561 47.723 1.00 53.94 O +ATOM 27080 CB SER O 54 29.635 45.260 49.992 1.00110.64 C +ATOM 27081 OG SER O 54 30.108 44.096 49.302 1.00167.70 O +ATOM 27082 N ASN O 55 29.425 45.630 46.747 1.00 86.68 N +ATOM 27083 CA ASN O 55 29.011 45.002 45.519 1.00 68.10 C +ATOM 27084 C ASN O 55 28.236 43.696 45.790 1.00 76.84 C +ATOM 27085 O ASN O 55 27.342 43.293 45.013 1.00 82.71 O +ATOM 27086 CB ASN O 55 30.234 44.713 44.679 1.00 55.85 C +ATOM 27087 CG ASN O 55 29.890 44.444 43.247 1.00 81.41 C +ATOM 27088 OD1 ASN O 55 28.809 44.755 42.760 1.00113.18 O +ATOM 27089 ND2 ASN O 55 30.828 43.874 42.551 1.00107.85 N +ATOM 27090 N PHE O 56 28.574 43.040 46.911 1.00 61.78 N +ATOM 27091 CA PHE O 56 28.095 41.684 47.222 1.00 55.64 C +ATOM 27092 C PHE O 56 26.909 41.714 48.154 1.00 60.72 C +ATOM 27093 O PHE O 56 26.430 40.649 48.567 1.00 60.96 O +ATOM 27094 CB PHE O 56 29.176 40.843 47.880 1.00 49.06 C +ATOM 27095 CG PHE O 56 30.384 40.688 47.041 1.00 73.64 C +ATOM 27096 CD1 PHE O 56 30.337 40.113 45.768 1.00 79.18 C +ATOM 27097 CD2 PHE O 56 31.566 41.253 47.451 1.00120.81 C +ATOM 27098 CE1 PHE O 56 31.450 40.109 44.926 1.00 77.44 C +ATOM 27099 CE2 PHE O 56 32.703 41.181 46.642 1.00139.75 C +ATOM 27100 CZ PHE O 56 32.637 40.631 45.361 1.00 89.27 C +ATOM 27101 N SER O 57 26.477 42.899 48.579 1.00 52.30 N +ATOM 27102 CA SER O 57 25.362 42.946 49.498 1.00 51.33 C +ATOM 27103 C SER O 57 24.087 42.668 48.697 1.00 50.17 C +ATOM 27104 O SER O 57 23.672 43.456 47.845 1.00 53.53 O +ATOM 27105 CB SER O 57 25.320 44.292 50.221 1.00 59.57 C +ATOM 27106 OG SER O 57 26.307 44.345 51.227 1.00 77.15 O +ATOM 27107 N THR O 58 23.432 41.570 49.010 1.00 55.55 N +ATOM 27108 CA THR O 58 22.170 41.252 48.371 1.00 77.71 C +ATOM 27109 C THR O 58 21.076 42.226 48.771 1.00101.65 C +ATOM 27110 O THR O 58 21.002 42.718 49.893 1.00113.47 O +ATOM 27111 CB THR O 58 21.706 39.846 48.758 1.00 71.07 C +ATOM 27112 OG1 THR O 58 21.486 39.790 50.182 1.00 49.41 O +ATOM 27113 CG2 THR O 58 22.762 38.892 48.393 1.00 82.38 C +ATOM 27114 N ALA O 59 20.125 42.412 47.898 1.00100.48 N +ATOM 27115 CA ALA O 59 19.059 43.306 48.259 1.00100.33 C +ATOM 27116 C ALA O 59 18.099 42.712 49.312 1.00 70.51 C +ATOM 27117 O ALA O 59 17.308 43.429 49.906 1.00 69.77 O +ATOM 27118 CB ALA O 59 18.324 43.739 47.002 1.00119.13 C +ATOM 27119 N VAL O 60 18.082 41.394 49.415 1.00 58.92 N +ATOM 27120 CA VAL O 60 17.066 40.685 50.162 1.00 55.79 C +ATOM 27121 C VAL O 60 17.769 39.668 50.994 1.00 70.29 C +ATOM 27122 O VAL O 60 18.741 39.014 50.538 1.00 88.29 O +ATOM 27123 CB VAL O 60 16.112 39.933 49.209 1.00 78.55 C +ATOM 27124 CG1 VAL O 60 15.072 39.122 49.972 1.00 77.60 C +ATOM 27125 CG2 VAL O 60 15.417 40.912 48.257 1.00114.54 C +ATOM 27126 N PRO O 61 17.289 39.473 52.212 1.00 84.58 N +ATOM 27127 CA PRO O 61 18.000 38.513 53.080 1.00114.76 C +ATOM 27128 C PRO O 61 17.845 37.075 52.611 1.00 98.75 C +ATOM 27129 O PRO O 61 16.795 36.724 52.050 1.00 72.71 O +ATOM 27130 CB PRO O 61 17.316 38.695 54.441 1.00143.10 C +ATOM 27131 CG PRO O 61 15.998 39.340 54.123 1.00124.50 C +ATOM 27132 CD PRO O 61 16.271 40.230 52.944 1.00 86.89 C +ATOM 27133 N GLN O 62 18.880 36.266 52.847 1.00 85.41 N +ATOM 27134 CA GLN O 62 18.943 34.913 52.292 1.00 95.09 C +ATOM 27135 C GLN O 62 18.298 33.945 53.248 1.00 84.42 C +ATOM 27136 O GLN O 62 18.759 32.823 53.384 1.00161.50 O +ATOM 27137 CB GLN O 62 20.413 34.479 52.024 1.00 85.37 C +ATOM 27138 CG GLN O 62 21.220 35.455 51.191 1.00 75.47 C +ATOM 27139 CD GLN O 62 20.571 35.710 49.841 1.00 73.54 C +ATOM 27140 OE1 GLN O 62 20.678 34.897 48.940 1.00 75.37 O +ATOM 27141 NE2 GLN O 62 19.889 36.840 49.705 1.00 64.15 N +ATOM 27142 N SER O 63 17.261 34.383 53.932 1.00 66.05 N +ATOM 27143 CA SER O 63 16.825 33.723 55.147 1.00 85.85 C +ATOM 27144 C SER O 63 15.392 33.212 55.045 1.00 85.63 C +ATOM 27145 O SER O 63 14.771 32.839 56.040 1.00108.87 O +ATOM 27146 CB SER O 63 17.018 34.681 56.360 1.00111.19 C +ATOM 27147 OG SER O 63 16.255 35.875 56.276 1.00118.90 O +ATOM 27148 N ALA O 64 14.840 33.307 53.848 1.00 91.36 N +ATOM 27149 CA ALA O 64 13.408 33.100 53.626 1.00 86.58 C +ATOM 27150 C ALA O 64 12.953 31.731 54.123 1.00 80.07 C +ATOM 27151 O ALA O 64 11.855 31.564 54.656 1.00 48.99 O +ATOM 27152 CB ALA O 64 13.119 33.262 52.144 1.00 93.25 C +ATOM 27153 N THR O 65 13.839 30.751 53.962 1.00115.40 N +ATOM 27154 CA THR O 65 13.559 29.371 54.333 1.00125.41 C +ATOM 27155 C THR O 65 13.107 29.294 55.780 1.00121.20 C +ATOM 27156 O THR O 65 12.111 28.640 56.107 1.00 98.25 O +ATOM 27157 CB THR O 65 14.830 28.520 54.168 1.00100.84 C +ATOM 27158 OG1 THR O 65 15.492 28.920 52.965 1.00 80.43 O +ATOM 27159 CG2 THR O 65 14.472 27.031 54.108 1.00113.98 C +ATOM 27160 N ALA O 66 13.880 29.925 56.650 1.00124.49 N +ATOM 27161 CA ALA O 66 13.644 29.803 58.073 1.00129.92 C +ATOM 27162 C ALA O 66 12.396 30.571 58.461 1.00 83.48 C +ATOM 27163 O ALA O 66 11.649 30.154 59.349 1.00 80.04 O +ATOM 27164 CB ALA O 66 14.862 30.288 58.842 1.00157.76 C +ATOM 27165 N MET O 67 12.153 31.658 57.744 1.00 83.59 N +ATOM 27166 CA MET O 67 10.964 32.464 57.973 1.00106.52 C +ATOM 27167 C MET O 67 9.719 31.648 57.630 1.00119.65 C +ATOM 27168 O MET O 67 8.701 31.692 58.351 1.00150.68 O +ATOM 27169 CB MET O 67 10.985 33.749 57.128 1.00 95.49 C +ATOM 27170 CG MET O 67 11.995 34.803 57.555 1.00 90.89 C +ATOM 27171 SD MET O 67 12.167 36.106 56.310 1.00 82.69 S +ATOM 27172 CE MET O 67 13.245 37.257 57.142 1.00106.21 C +ATOM 27173 N LEU O 68 9.801 30.897 56.537 1.00 95.73 N +ATOM 27174 CA LEU O 68 8.661 30.110 56.111 1.00 94.99 C +ATOM 27175 C LEU O 68 8.396 29.018 57.117 1.00 90.37 C +ATOM 27176 O LEU O 68 7.235 28.761 57.456 1.00107.47 O +ATOM 27177 CB LEU O 68 8.884 29.484 54.738 1.00 94.83 C +ATOM 27178 CG LEU O 68 7.812 28.432 54.372 1.00 76.21 C +ATOM 27179 CD1 LEU O 68 6.455 29.060 54.181 1.00 64.70 C +ATOM 27180 CD2 LEU O 68 8.201 27.654 53.127 1.00 87.98 C +ATOM 27181 N VAL O 69 9.452 28.351 57.575 1.00 90.75 N +ATOM 27182 CA VAL O 69 9.285 27.260 58.551 1.00126.63 C +ATOM 27183 C VAL O 69 8.648 27.799 59.838 1.00116.48 C +ATOM 27184 O VAL O 69 7.714 27.213 60.382 1.00115.81 O +ATOM 27185 CB VAL O 69 10.621 26.588 58.922 1.00156.39 C +ATOM 27186 CG1 VAL O 69 10.407 25.612 60.068 1.00164.41 C +ATOM 27187 CG2 VAL O 69 11.232 25.855 57.737 1.00161.81 C +ATOM 27188 N THR O 70 9.117 28.960 60.270 1.00123.38 N +ATOM 27189 CA THR O 70 8.570 29.621 61.448 1.00135.12 C +ATOM 27190 C THR O 70 7.098 30.002 61.265 1.00140.66 C +ATOM 27191 O THR O 70 6.270 29.758 62.144 1.00138.68 O +ATOM 27192 CB THR O 70 9.391 30.877 61.788 1.00153.48 C +ATOM 27193 OG1 THR O 70 10.770 30.497 61.909 1.00202.89 O +ATOM 27194 CG2 THR O 70 8.895 31.520 63.095 1.00132.19 C +ATOM 27195 N ALA O 71 6.769 30.573 60.106 1.00128.21 N +ATOM 27196 CA ALA O 71 5.381 30.917 59.803 1.00124.98 C +ATOM 27197 C ALA O 71 4.487 29.667 59.779 1.00128.74 C +ATOM 27198 O ALA O 71 3.365 29.669 60.311 1.00154.91 O +ATOM 27199 CB ALA O 71 5.293 31.655 58.473 1.00107.33 C +ATOM 27200 N LEU O 72 4.990 28.596 59.170 1.00105.83 N +ATOM 27201 CA LEU O 72 4.264 27.322 59.148 1.00 87.43 C +ATOM 27202 C LEU O 72 4.007 26.789 60.561 1.00107.64 C +ATOM 27203 O LEU O 72 3.044 26.052 60.774 1.00108.30 O +ATOM 27204 CB LEU O 72 5.019 26.271 58.336 1.00 61.58 C +ATOM 27205 CG LEU O 72 5.121 26.561 56.849 1.00 56.25 C +ATOM 27206 CD1 LEU O 72 6.200 25.710 56.255 1.00 55.07 C +ATOM 27207 CD2 LEU O 72 3.815 26.277 56.144 1.00 87.32 C +ATOM 27208 N LYS O 73 4.874 27.148 61.514 1.00115.37 N +ATOM 27209 CA LYS O 73 4.711 26.683 62.895 1.00111.21 C +ATOM 27210 C LYS O 73 3.762 27.556 63.668 1.00111.64 C +ATOM 27211 O LYS O 73 2.871 27.057 64.348 1.00105.51 O +ATOM 27212 CB LYS O 73 6.038 26.632 63.633 1.00110.00 C +ATOM 27213 CG LYS O 73 5.956 25.879 64.959 1.00127.08 C +ATOM 27214 CD LYS O 73 7.309 25.851 65.672 1.00177.33 C +ATOM 27215 CE LYS O 73 7.158 25.748 67.182 1.00201.73 C +ATOM 27216 NZ LYS O 73 7.663 24.458 67.733 1.00215.92 N +ATOM 27217 N ASP O 74 3.929 28.865 63.527 1.00113.44 N +ATOM 27218 CA ASP O 74 3.091 29.812 64.246 1.00132.73 C +ATOM 27219 C ASP O 74 1.605 29.654 63.915 1.00140.82 C +ATOM 27220 O ASP O 74 0.738 29.961 64.750 1.00170.46 O +ATOM 27221 CB ASP O 74 3.543 31.247 63.960 1.00134.07 C +ATOM 27222 CG ASP O 74 4.935 31.551 64.523 1.00126.17 C +ATOM 27223 OD1 ASP O 74 5.317 30.990 65.586 1.00117.05 O +ATOM 27224 OD2 ASP O 74 5.584 32.470 63.969 1.00101.81 O +ATOM 27225 N SER O 75 1.313 29.188 62.700 1.00137.30 N +ATOM 27226 CA SER O 75 -0.069 29.051 62.220 1.00147.27 C +ATOM 27227 C SER O 75 -0.866 28.012 63.018 1.00140.66 C +ATOM 27228 O SER O 75 -2.099 28.081 63.061 1.00119.01 O +ATOM 27229 CB SER O 75 -0.094 28.664 60.737 1.00142.70 C +ATOM 27230 OG SER O 75 0.018 27.260 60.577 1.00124.18 O +ATOM 27231 N ARG O 76 -0.148 27.062 63.622 1.00119.54 N +ATOM 27232 CA ARG O 76 -0.733 25.956 64.382 1.00122.33 C +ATOM 27233 C ARG O 76 -1.570 25.062 63.496 1.00108.63 C +ATOM 27234 O ARG O 76 -2.615 24.566 63.890 1.00 78.00 O +ATOM 27235 CB ARG O 76 -1.550 26.472 65.554 1.00151.55 C +ATOM 27236 CG ARG O 76 -0.757 27.270 66.581 1.00171.92 C +ATOM 27237 CD ARG O 76 -1.666 27.702 67.729 1.00213.51 C +ATOM 27238 NE ARG O 76 -2.642 28.717 67.304 1.00227.13 N +ATOM 27239 CZ ARG O 76 -3.889 28.469 66.894 1.00199.38 C +ATOM 27240 NH1 ARG O 76 -4.364 27.225 66.840 1.00210.07 N +ATOM 27241 NH2 ARG O 76 -4.661 29.475 66.522 1.00155.65 N +ATOM 27242 N TRP O 77 -1.123 24.935 62.257 1.00130.48 N +ATOM 27243 CA TRP O 77 -1.695 23.989 61.312 1.00128.18 C +ATOM 27244 C TRP O 77 -0.681 22.894 60.978 1.00158.31 C +ATOM 27245 O TRP O 77 -1.050 21.742 60.724 1.00166.82 O +ATOM 27246 CB TRP O 77 -2.102 24.724 60.026 1.00117.80 C +ATOM 27247 CG TRP O 77 -3.514 25.192 60.011 1.00113.51 C +ATOM 27248 CD1 TRP O 77 -4.018 26.271 60.653 1.00116.22 C +ATOM 27249 CD2 TRP O 77 -4.603 24.612 59.284 1.00112.50 C +ATOM 27250 NE1 TRP O 77 -5.358 26.388 60.394 1.00125.13 N +ATOM 27251 CE2 TRP O 77 -5.738 25.377 59.554 1.00109.43 C +ATOM 27252 CE3 TRP O 77 -4.725 23.509 58.442 1.00134.61 C +ATOM 27253 CZ2 TRP O 77 -6.982 25.080 59.010 1.00111.69 C +ATOM 27254 CZ3 TRP O 77 -5.966 23.216 57.903 1.00119.88 C +ATOM 27255 CH2 TRP O 77 -7.073 24.006 58.180 1.00105.97 C +ATOM 27256 N PHE O 78 0.599 23.274 60.954 1.00188.27 N +ATOM 27257 CA PHE O 78 1.691 22.404 60.498 1.00157.47 C +ATOM 27258 C PHE O 78 2.750 22.158 61.584 1.00126.71 C +ATOM 27259 O PHE O 78 3.092 23.071 62.343 1.00135.66 O +ATOM 27260 CB PHE O 78 2.399 23.045 59.309 1.00128.07 C +ATOM 27261 CG PHE O 78 1.490 23.395 58.179 1.00110.45 C +ATOM 27262 CD1 PHE O 78 0.968 22.410 57.350 1.00113.94 C +ATOM 27263 CD2 PHE O 78 1.154 24.705 57.947 1.00101.71 C +ATOM 27264 CE1 PHE O 78 0.130 22.732 56.299 1.00110.49 C +ATOM 27265 CE2 PHE O 78 0.344 25.041 56.881 1.00106.77 C +ATOM 27266 CZ PHE O 78 -0.167 24.054 56.054 1.00107.15 C +ATOM 27267 N ILE O 79 3.270 20.935 61.623 1.00 86.32 N +ATOM 27268 CA ILE O 79 4.493 20.624 62.319 1.00 84.13 C +ATOM 27269 C ILE O 79 5.582 20.639 61.260 1.00102.28 C +ATOM 27270 O ILE O 79 5.483 19.930 60.248 1.00107.63 O +ATOM 27271 CB ILE O 79 4.436 19.222 62.925 1.00101.58 C +ATOM 27272 CG1 ILE O 79 3.151 19.023 63.723 1.00112.87 C +ATOM 27273 CG2 ILE O 79 5.646 18.973 63.822 1.00121.75 C +ATOM 27274 CD1 ILE O 79 2.748 17.569 63.883 1.00129.37 C +ATOM 27275 N PRO O 80 6.626 21.456 61.466 1.00115.10 N +ATOM 27276 CA PRO O 80 7.692 21.425 60.467 1.00114.69 C +ATOM 27277 C PRO O 80 8.772 20.428 60.838 1.00126.75 C +ATOM 27278 O PRO O 80 9.141 20.330 62.005 1.00107.96 O +ATOM 27279 CB PRO O 80 8.250 22.838 60.498 1.00 84.98 C +ATOM 27280 CG PRO O 80 7.155 23.649 61.056 1.00109.91 C +ATOM 27281 CD PRO O 80 6.563 22.763 62.119 1.00112.93 C +ATOM 27282 N LEU O 81 9.159 19.611 59.869 1.00114.58 N +ATOM 27283 CA LEU O 81 10.220 18.674 60.059 1.00 93.48 C +ATOM 27284 C LEU O 81 11.485 19.316 59.544 1.00 91.86 C +ATOM 27285 O LEU O 81 11.467 20.062 58.550 1.00102.40 O +ATOM 27286 CB LEU O 81 9.910 17.395 59.317 1.00107.16 C +ATOM 27287 CG LEU O 81 8.572 16.810 59.751 1.00131.43 C +ATOM 27288 CD1 LEU O 81 8.272 15.602 58.901 1.00120.49 C +ATOM 27289 CD2 LEU O 81 8.608 16.426 61.223 1.00155.23 C +ATOM 27290 N GLU O 82 12.560 19.093 60.289 1.00 71.98 N +ATOM 27291 CA GLU O 82 13.845 19.739 60.012 1.00 60.76 C +ATOM 27292 C GLU O 82 14.522 19.023 58.849 1.00 53.07 C +ATOM 27293 O GLU O 82 15.041 17.908 58.997 1.00 55.67 O +ATOM 27294 CB GLU O 82 14.766 19.757 61.280 1.00 66.67 C +ATOM 27295 CG GLU O 82 16.161 20.373 61.096 1.00 56.08 C +ATOM 27296 CD GLU O 82 16.151 21.892 60.842 1.00 83.22 C +ATOM 27297 OE1 GLU O 82 15.322 22.440 60.012 1.00 77.65 O +ATOM 27298 OE2 GLU O 82 16.960 22.583 61.518 1.00 94.84 O +ATOM 27299 N ARG O 83 14.625 19.739 57.750 1.00 55.18 N +ATOM 27300 CA ARG O 83 15.406 19.303 56.605 1.00 54.29 C +ATOM 27301 C ARG O 83 16.453 20.351 56.163 1.00 78.20 C +ATOM 27302 O ARG O 83 17.409 20.006 55.483 1.00 96.55 O +ATOM 27303 CB ARG O 83 14.474 19.011 55.453 1.00 58.07 C +ATOM 27304 CG ARG O 83 13.399 17.998 55.781 1.00 66.81 C +ATOM 27305 CD ARG O 83 13.943 16.613 55.964 1.00 68.96 C +ATOM 27306 NE ARG O 83 12.822 15.662 56.031 1.00 85.58 N +ATOM 27307 CZ ARG O 83 12.337 15.093 57.141 1.00 77.92 C +ATOM 27308 NH1 ARG O 83 12.892 15.337 58.331 1.00 65.45 N +ATOM 27309 NH2 ARG O 83 11.291 14.276 57.046 1.00 64.95 N +ATOM 27310 N GLN O 84 16.324 21.622 56.564 1.00119.65 N +ATOM 27311 CA GLN O 84 17.361 22.611 56.207 1.00116.38 C +ATOM 27312 C GLN O 84 18.744 22.172 56.732 1.00121.37 C +ATOM 27313 O GLN O 84 19.725 22.234 56.022 1.00193.39 O +ATOM 27314 CB GLN O 84 17.026 24.034 56.693 1.00128.96 C +ATOM 27315 CG GLN O 84 17.560 25.156 55.795 1.00130.92 C +ATOM 27316 CD GLN O 84 17.290 26.561 56.338 1.00146.06 C +ATOM 27317 OE1 GLN O 84 16.277 26.799 56.985 1.00158.40 O +ATOM 27318 NE2 GLN O 84 18.250 27.473 56.146 1.00135.69 N +ATOM 27319 N GLY O 85 18.822 21.661 57.947 1.00 88.94 N +ATOM 27320 CA GLY O 85 20.104 21.158 58.430 1.00 76.56 C +ATOM 27321 C GLY O 85 20.186 19.631 58.517 1.00 84.24 C +ATOM 27322 O GLY O 85 20.668 19.083 59.520 1.00104.49 O +ATOM 27323 N LEU O 86 19.627 18.923 57.541 1.00 67.16 N +ATOM 27324 CA LEU O 86 19.346 17.486 57.711 1.00 77.91 C +ATOM 27325 C LEU O 86 20.633 16.760 58.031 1.00 67.75 C +ATOM 27326 O LEU O 86 20.629 15.714 58.688 1.00 73.25 O +ATOM 27327 CB LEU O 86 18.659 16.910 56.445 1.00101.03 C +ATOM 27328 CG LEU O 86 18.463 15.384 56.260 1.00 96.63 C +ATOM 27329 CD1 LEU O 86 17.644 14.759 57.375 1.00 85.30 C +ATOM 27330 CD2 LEU O 86 17.816 15.097 54.893 1.00 77.68 C +ATOM 27331 N GLN O 87 21.724 17.254 57.459 1.00 68.09 N +ATOM 27332 CA GLN O 87 22.976 16.510 57.487 1.00 95.52 C +ATOM 27333 C GLN O 87 23.441 16.378 58.947 1.00 98.77 C +ATOM 27334 O GLN O 87 23.897 15.293 59.383 1.00 76.92 O +ATOM 27335 CB GLN O 87 24.025 17.193 56.588 1.00 99.94 C +ATOM 27336 CG GLN O 87 25.023 16.224 55.945 1.00105.39 C +ATOM 27337 CD GLN O 87 24.379 14.942 55.387 1.00103.92 C +ATOM 27338 OE1 GLN O 87 23.490 14.994 54.542 1.00 83.74 O +ATOM 27339 NE2 GLN O 87 24.846 13.787 55.857 1.00102.83 N +ATOM 27340 N ASN O 88 23.254 17.458 59.707 1.00 84.36 N +ATOM 27341 CA ASN O 88 23.666 17.489 61.118 1.00 80.73 C +ATOM 27342 C ASN O 88 22.801 16.583 61.966 1.00 65.61 C +ATOM 27343 O ASN O 88 23.277 15.930 62.903 1.00 62.55 O +ATOM 27344 CB ASN O 88 23.549 18.893 61.684 1.00 66.17 C +ATOM 27345 CG ASN O 88 24.389 19.900 60.940 1.00 61.15 C +ATOM 27346 OD1 ASN O 88 25.464 19.583 60.453 1.00 61.45 O +ATOM 27347 ND2 ASN O 88 23.859 21.092 60.779 1.00 79.80 N +ATOM 27348 N LEU O 89 21.544 16.503 61.571 1.00 53.05 N +ATOM 27349 CA LEU O 89 20.598 15.659 62.255 1.00 60.54 C +ATOM 27350 C LEU O 89 21.058 14.195 62.126 1.00 70.85 C +ATOM 27351 O LEU O 89 21.053 13.416 63.085 1.00 64.99 O +ATOM 27352 CB LEU O 89 19.208 15.901 61.628 1.00 56.18 C +ATOM 27353 CG LEU O 89 17.988 15.742 62.496 1.00 64.17 C +ATOM 27354 CD1 LEU O 89 17.141 14.609 62.015 1.00 62.69 C +ATOM 27355 CD2 LEU O 89 18.365 15.510 63.969 1.00 97.19 C +ATOM 27356 N LEU O 90 21.476 13.828 60.915 1.00 93.89 N +ATOM 27357 CA LEU O 90 21.847 12.430 60.608 1.00 75.95 C +ATOM 27358 C LEU O 90 23.163 12.093 61.247 1.00 74.82 C +ATOM 27359 O LEU O 90 23.389 10.956 61.681 1.00 80.67 O +ATOM 27360 CB LEU O 90 21.955 12.228 59.107 1.00 87.14 C +ATOM 27361 CG LEU O 90 20.664 12.478 58.314 1.00 95.52 C +ATOM 27362 CD1 LEU O 90 20.992 12.716 56.850 1.00 69.38 C +ATOM 27363 CD2 LEU O 90 19.731 11.288 58.516 1.00119.27 C +ATOM 27364 N ASN O 91 24.000 13.117 61.395 1.00 86.73 N +ATOM 27365 CA ASN O 91 25.267 12.971 62.098 1.00 99.31 C +ATOM 27366 C ASN O 91 25.072 12.677 63.608 1.00 85.58 C +ATOM 27367 O ASN O 91 25.669 11.748 64.155 1.00 53.43 O +ATOM 27368 CB ASN O 91 26.085 14.247 61.901 1.00 82.66 C +ATOM 27369 CG ASN O 91 27.326 14.054 61.105 1.00 94.82 C +ATOM 27370 OD1 ASN O 91 27.527 13.046 60.416 1.00 83.90 O +ATOM 27371 ND2 ASN O 91 28.233 15.012 61.262 1.00138.05 N +ATOM 27372 N GLU O 92 24.243 13.474 64.271 1.00 81.75 N +ATOM 27373 CA GLU O 92 23.980 13.244 65.682 1.00 92.52 C +ATOM 27374 C GLU O 92 23.450 11.834 65.877 1.00 73.16 C +ATOM 27375 O GLU O 92 23.666 11.204 66.903 1.00 66.57 O +ATOM 27376 CB GLU O 92 23.006 14.311 66.243 1.00118.75 C +ATOM 27377 CG GLU O 92 23.686 15.520 66.891 1.00111.98 C +ATOM 27378 CD GLU O 92 24.706 15.151 67.980 1.00 84.64 C +ATOM 27379 OE1 GLU O 92 24.373 14.455 68.966 1.00 52.66 O +ATOM 27380 OE2 GLU O 92 25.886 15.552 67.827 1.00 90.86 O +ATOM 27381 N ARG O 93 22.643 11.395 64.934 1.00 70.78 N +ATOM 27382 CA ARG O 93 22.027 10.095 65.048 1.00 84.09 C +ATOM 27383 C ARG O 93 23.087 9.018 64.883 1.00 75.11 C +ATOM 27384 O ARG O 93 23.006 7.953 65.492 1.00 64.06 O +ATOM 27385 CB ARG O 93 20.846 9.985 64.052 1.00108.28 C +ATOM 27386 CG ARG O 93 19.651 10.864 64.475 1.00109.25 C +ATOM 27387 CD ARG O 93 18.616 11.078 63.385 1.00108.02 C +ATOM 27388 NE ARG O 93 17.447 10.230 63.543 1.00112.00 N +ATOM 27389 CZ ARG O 93 17.264 9.061 62.922 1.00115.13 C +ATOM 27390 NH1 ARG O 93 18.170 8.546 62.087 1.00 90.28 N +ATOM 27391 NH2 ARG O 93 16.136 8.413 63.145 1.00132.16 N +ATOM 27392 N LYS O 94 24.099 9.297 64.070 1.00 86.88 N +ATOM 27393 CA LYS O 94 25.215 8.355 63.921 1.00101.31 C +ATOM 27394 C LYS O 94 25.959 8.253 65.238 1.00102.77 C +ATOM 27395 O LYS O 94 26.347 7.148 65.649 1.00123.91 O +ATOM 27396 CB LYS O 94 26.193 8.826 62.846 1.00108.42 C +ATOM 27397 CG LYS O 94 25.895 8.363 61.423 1.00111.77 C +ATOM 27398 CD LYS O 94 26.818 9.067 60.437 1.00117.30 C +ATOM 27399 CE LYS O 94 26.923 8.348 59.102 1.00113.09 C +ATOM 27400 NZ LYS O 94 27.542 9.249 58.090 1.00127.38 N +ATOM 27401 N ILE O 95 26.142 9.400 65.901 1.00 74.43 N +ATOM 27402 CA ILE O 95 26.919 9.415 67.128 1.00 59.00 C +ATOM 27403 C ILE O 95 26.159 8.685 68.216 1.00 67.99 C +ATOM 27404 O ILE O 95 26.767 8.010 69.081 1.00 43.24 O +ATOM 27405 CB ILE O 95 27.233 10.820 67.614 1.00 67.97 C +ATOM 27406 CG1 ILE O 95 27.791 11.673 66.485 1.00100.61 C +ATOM 27407 CG2 ILE O 95 28.278 10.719 68.700 1.00 69.05 C +ATOM 27408 CD1 ILE O 95 28.451 12.974 66.917 1.00123.03 C +ATOM 27409 N ILE O 96 24.823 8.893 68.219 1.00 89.85 N +ATOM 27410 CA ILE O 96 23.910 8.215 69.160 1.00 71.82 C +ATOM 27411 C ILE O 96 24.036 6.733 69.003 1.00 61.52 C +ATOM 27412 O ILE O 96 24.427 6.041 69.945 1.00 59.84 O +ATOM 27413 CB ILE O 96 22.440 8.594 68.947 1.00 53.71 C +ATOM 27414 CG1 ILE O 96 22.207 10.055 69.366 1.00 75.55 C +ATOM 27415 CG2 ILE O 96 21.574 7.724 69.824 1.00 50.96 C +ATOM 27416 CD1 ILE O 96 20.765 10.496 69.261 1.00 86.18 C +ATOM 27417 N ARG O 97 23.787 6.267 67.793 1.00 61.05 N +ATOM 27418 CA ARG O 97 23.849 4.838 67.520 1.00 82.94 C +ATOM 27419 C ARG O 97 25.220 4.229 67.847 1.00 98.71 C +ATOM 27420 O ARG O 97 25.323 3.060 68.236 1.00116.14 O +ATOM 27421 CB ARG O 97 23.494 4.548 66.059 1.00 96.28 C +ATOM 27422 CG ARG O 97 22.076 4.032 65.844 1.00109.07 C +ATOM 27423 CD ARG O 97 21.809 3.702 64.376 1.00 95.93 C +ATOM 27424 NE ARG O 97 21.482 4.886 63.586 1.00 81.64 N +ATOM 27425 CZ ARG O 97 20.245 5.275 63.282 1.00 93.74 C +ATOM 27426 NH1 ARG O 97 19.179 4.571 63.677 1.00 70.24 N +ATOM 27427 NH2 ARG O 97 20.076 6.395 62.581 1.00122.19 N +ATOM 27428 N ALA O 98 26.276 5.015 67.686 1.00105.36 N +ATOM 27429 CA ALA O 98 27.618 4.537 67.989 1.00104.86 C +ATOM 27430 C ALA O 98 27.839 4.495 69.499 1.00100.17 C +ATOM 27431 O ALA O 98 28.632 3.689 69.988 1.00 86.96 O +ATOM 27432 CB ALA O 98 28.645 5.428 67.308 1.00122.30 C +ATOM 27433 N ALA O 99 27.132 5.372 70.220 1.00 96.14 N +ATOM 27434 CA ALA O 99 27.235 5.468 71.689 1.00 91.93 C +ATOM 27435 C ALA O 99 26.628 4.283 72.395 1.00 92.27 C +ATOM 27436 O ALA O 99 27.274 3.619 73.209 1.00141.97 O +ATOM 27437 CB ALA O 99 26.537 6.711 72.180 1.00103.25 C +ATOM 27438 N GLN O 100 25.404 3.946 72.006 1.00103.16 N +ATOM 27439 CA GLN O 100 24.601 2.975 72.764 1.00105.70 C +ATOM 27440 C GLN O 100 24.451 1.577 72.139 1.00 95.47 C +ATOM 27441 O GLN O 100 23.726 0.735 72.659 1.00 95.38 O +ATOM 27442 CB GLN O 100 23.217 3.558 73.036 1.00 99.12 C +ATOM 27443 CG GLN O 100 22.564 4.233 71.853 1.00 86.57 C +ATOM 27444 CD GLN O 100 21.590 5.316 72.276 1.00 77.36 C +ATOM 27445 OE1 GLN O 100 21.960 6.334 72.908 1.00 63.01 O +ATOM 27446 NE2 GLN O 100 20.337 5.135 71.874 1.00 70.63 N +ATOM 27447 N GLU O 101 25.190 1.312 71.072 1.00107.37 N +ATOM 27448 CA GLU O 101 25.120 0.016 70.408 1.00116.86 C +ATOM 27449 C GLU O 101 25.656 -1.128 71.270 1.00122.33 C +ATOM 27450 O GLU O 101 25.302 -2.292 71.050 1.00134.54 O +ATOM 27451 CB GLU O 101 25.852 0.061 69.055 1.00131.09 C +ATOM 27452 CG GLU O 101 27.288 0.586 69.110 1.00129.00 C +ATOM 27453 CD GLU O 101 27.972 0.555 67.756 1.00132.22 C +ATOM 27454 OE1 GLU O 101 27.262 0.408 66.729 1.00134.83 O +ATOM 27455 OE2 GLU O 101 29.225 0.601 67.709 1.00140.15 O +ATOM 27456 N ASN O 102 26.543 -0.817 72.212 1.00118.72 N +ATOM 27457 CA ASN O 102 27.171 -1.854 73.022 1.00122.94 C +ATOM 27458 C ASN O 102 26.421 -2.128 74.313 1.00129.81 C +ATOM 27459 O ASN O 102 26.799 -3.022 75.073 1.00141.74 O +ATOM 27460 CB ASN O 102 28.610 -1.480 73.347 1.00119.78 C +ATOM 27461 CG ASN O 102 29.513 -1.581 72.148 1.00142.41 C +ATOM 27462 OD1 ASN O 102 29.939 -2.683 71.756 1.00190.82 O +ATOM 27463 ND2 ASN O 102 29.761 -0.444 71.508 1.00151.76 N +ATOM 27464 N GLY O 103 25.355 -1.376 74.565 1.00117.99 N +ATOM 27465 CA GLY O 103 24.569 -1.575 75.780 1.00110.11 C +ATOM 27466 C GLY O 103 25.371 -1.388 77.049 1.00106.43 C +ATOM 27467 O GLY O 103 25.122 -2.042 78.069 1.00136.01 O +ATOM 27468 N THR O 104 26.333 -0.475 77.006 1.00106.90 N +ATOM 27469 CA THR O 104 26.987 -0.018 78.219 1.00107.98 C +ATOM 27470 C THR O 104 26.399 1.326 78.660 1.00109.26 C +ATOM 27471 O THR O 104 26.384 1.622 79.850 1.00115.48 O +ATOM 27472 CB THR O 104 28.518 0.098 78.053 1.00 99.74 C +ATOM 27473 OG1 THR O 104 28.832 1.125 77.099 1.00 84.14 O +ATOM 27474 CG2 THR O 104 29.111 -1.237 77.618 1.00 87.47 C +ATOM 27475 N VAL O 105 25.851 2.102 77.725 1.00100.37 N +ATOM 27476 CA VAL O 105 25.431 3.473 78.042 1.00123.33 C +ATOM 27477 C VAL O 105 24.355 3.472 79.123 1.00137.11 C +ATOM 27478 O VAL O 105 23.463 2.608 79.140 1.00122.51 O +ATOM 27479 CB VAL O 105 24.978 4.283 76.789 1.00150.64 C +ATOM 27480 CG1 VAL O 105 23.855 5.265 77.117 1.00138.98 C +ATOM 27481 CG2 VAL O 105 26.164 5.041 76.171 1.00157.34 C +ATOM 27482 N ALA O 106 24.480 4.441 80.031 1.00157.03 N +ATOM 27483 CA ALA O 106 23.661 4.524 81.234 1.00149.14 C +ATOM 27484 C ALA O 106 22.186 4.696 80.884 1.00165.37 C +ATOM 27485 O ALA O 106 21.831 5.509 80.028 1.00173.87 O +ATOM 27486 CB ALA O 106 24.136 5.676 82.104 1.00125.12 C +ATOM 27487 N ILE O 107 21.333 3.922 81.553 1.00163.26 N +ATOM 27488 CA ILE O 107 19.903 3.860 81.230 1.00159.48 C +ATOM 27489 C ILE O 107 19.203 5.239 81.328 1.00146.56 C +ATOM 27490 O ILE O 107 18.251 5.522 80.596 1.00 96.10 O +ATOM 27491 CB ILE O 107 19.188 2.815 82.129 1.00144.62 C +ATOM 27492 CG1 ILE O 107 17.776 2.512 81.609 1.00141.96 C +ATOM 27493 CG2 ILE O 107 19.138 3.297 83.576 1.00141.38 C +ATOM 27494 CD1 ILE O 107 17.720 2.008 80.179 1.00139.74 C +ATOM 27495 N ASN O 108 19.694 6.090 82.224 1.00153.61 N +ATOM 27496 CA ASN O 108 19.204 7.467 82.351 1.00149.62 C +ATOM 27497 C ASN O 108 19.620 8.314 81.157 1.00143.49 C +ATOM 27498 O ASN O 108 18.894 9.207 80.724 1.00158.13 O +ATOM 27499 CB ASN O 108 19.757 8.119 83.625 1.00165.60 C +ATOM 27500 CG ASN O 108 20.000 7.116 84.737 1.00184.06 C +ATOM 27501 OD1 ASN O 108 19.096 6.800 85.510 1.00236.79 O +ATOM 27502 ND2 ASN O 108 21.225 6.604 84.821 1.00177.76 N +ATOM 27503 N ASN O 109 20.815 8.037 80.650 1.00141.31 N +ATOM 27504 CA ASN O 109 21.420 8.824 79.583 1.00151.25 C +ATOM 27505 C ASN O 109 21.000 8.368 78.182 1.00141.84 C +ATOM 27506 O ASN O 109 21.150 9.114 77.207 1.00112.84 O +ATOM 27507 CB ASN O 109 22.944 8.762 79.702 1.00150.60 C +ATOM 27508 CG ASN O 109 23.558 10.115 79.990 1.00176.66 C +ATOM 27509 OD1 ASN O 109 24.278 10.669 79.161 1.00183.74 O +ATOM 27510 ND2 ASN O 109 23.234 10.680 81.150 1.00202.66 N +ATOM 27511 N ARG O 110 20.448 7.158 78.104 1.00135.83 N +ATOM 27512 CA ARG O 110 20.092 6.511 76.830 1.00108.62 C +ATOM 27513 C ARG O 110 19.143 7.377 75.991 1.00 93.96 C +ATOM 27514 O ARG O 110 18.163 7.914 76.513 1.00104.53 O +ATOM 27515 CB ARG O 110 19.421 5.156 77.120 1.00105.21 C +ATOM 27516 CG ARG O 110 19.509 4.141 75.997 1.00119.66 C +ATOM 27517 CD ARG O 110 19.629 2.719 76.522 1.00122.74 C +ATOM 27518 NE ARG O 110 18.316 2.098 76.728 1.00154.02 N +ATOM 27519 CZ ARG O 110 17.883 0.990 76.115 1.00171.13 C +ATOM 27520 NH1 ARG O 110 18.645 0.337 75.232 1.00155.43 N +ATOM 27521 NH2 ARG O 110 16.674 0.515 76.403 1.00173.26 N +ATOM 27522 N ILE O 111 19.426 7.511 74.698 1.00 78.74 N +ATOM 27523 CA ILE O 111 18.505 8.202 73.792 1.00 76.95 C +ATOM 27524 C ILE O 111 17.826 7.218 72.849 1.00 84.80 C +ATOM 27525 O ILE O 111 18.509 6.587 72.058 1.00 76.14 O +ATOM 27526 CB ILE O 111 19.222 9.250 72.948 1.00 70.56 C +ATOM 27527 CG1 ILE O 111 19.782 10.338 73.856 1.00 86.99 C +ATOM 27528 CG2 ILE O 111 18.258 9.856 71.936 1.00 68.18 C +ATOM 27529 CD1 ILE O 111 20.760 11.280 73.175 1.00113.60 C +ATOM 27530 N PRO O 112 16.482 7.092 72.926 1.00105.28 N +ATOM 27531 CA PRO O 112 15.768 6.121 72.104 1.00 96.93 C +ATOM 27532 C PRO O 112 15.552 6.684 70.711 1.00122.60 C +ATOM 27533 O PRO O 112 15.105 7.833 70.556 1.00 85.81 O +ATOM 27534 CB PRO O 112 14.446 5.948 72.831 1.00 81.11 C +ATOM 27535 CG PRO O 112 14.209 7.280 73.467 1.00101.79 C +ATOM 27536 CD PRO O 112 15.555 7.906 73.734 1.00116.72 C +ATOM 27537 N LEU O 113 15.945 5.900 69.708 1.00159.44 N +ATOM 27538 CA LEU O 113 15.957 6.362 68.329 1.00138.94 C +ATOM 27539 C LEU O 113 14.838 5.752 67.532 1.00112.45 C +ATOM 27540 O LEU O 113 14.531 4.551 67.618 1.00117.99 O +ATOM 27541 CB LEU O 113 17.288 6.071 67.643 1.00120.87 C +ATOM 27542 CG LEU O 113 18.347 7.145 67.841 1.00124.00 C +ATOM 27543 CD1 LEU O 113 19.555 6.741 67.023 1.00144.56 C +ATOM 27544 CD2 LEU O 113 17.873 8.539 67.434 1.00124.52 C +ATOM 27545 N GLN O 114 14.263 6.604 66.705 1.00 90.16 N +ATOM 27546 CA GLN O 114 13.056 6.287 66.012 1.00100.69 C +ATOM 27547 C GLN O 114 13.268 6.814 64.623 1.00 97.01 C +ATOM 27548 O GLN O 114 13.977 7.815 64.452 1.00139.45 O +ATOM 27549 CB GLN O 114 11.894 6.990 66.704 1.00 94.49 C +ATOM 27550 CG GLN O 114 10.581 6.260 66.585 1.00 96.69 C +ATOM 27551 CD GLN O 114 9.426 7.218 66.642 1.00107.26 C +ATOM 27552 OE1 GLN O 114 8.404 6.999 65.984 1.00131.96 O +ATOM 27553 NE2 GLN O 114 9.591 8.314 67.391 1.00108.89 N +ATOM 27554 N SER O 115 12.696 6.133 63.637 1.00 77.41 N +ATOM 27555 CA SER O 115 12.855 6.542 62.261 1.00102.17 C +ATOM 27556 C SER O 115 12.446 8.013 62.074 1.00102.95 C +ATOM 27557 O SER O 115 11.646 8.556 62.850 1.00 70.12 O +ATOM 27558 CB SER O 115 12.028 5.647 61.333 1.00115.49 C +ATOM 27559 OG SER O 115 10.666 5.606 61.735 1.00124.96 O +ATOM 27560 N LEU O 116 13.020 8.673 61.069 1.00 99.35 N +ATOM 27561 CA LEU O 116 12.850 10.101 61.005 1.00 97.57 C +ATOM 27562 C LEU O 116 11.417 10.321 60.599 1.00111.38 C +ATOM 27563 O LEU O 116 10.981 9.766 59.587 1.00157.82 O +ATOM 27564 CB LEU O 116 13.804 10.748 60.002 1.00101.87 C +ATOM 27565 CG LEU O 116 15.285 10.705 60.356 1.00 86.68 C +ATOM 27566 CD1 LEU O 116 15.981 9.501 59.713 1.00103.24 C +ATOM 27567 CD2 LEU O 116 15.925 12.009 59.899 1.00 79.60 C +ATOM 27568 N THR O 117 10.695 11.127 61.372 1.00111.82 N +ATOM 27569 CA THR O 117 9.313 11.467 61.046 1.00112.58 C +ATOM 27570 C THR O 117 9.279 12.033 59.642 1.00 85.74 C +ATOM 27571 O THR O 117 10.069 12.922 59.320 1.00102.05 O +ATOM 27572 CB THR O 117 8.719 12.507 62.023 1.00113.35 C +ATOM 27573 OG1 THR O 117 8.882 12.044 63.368 1.00161.61 O +ATOM 27574 CG2 THR O 117 7.239 12.706 61.755 1.00109.11 C +ATOM 27575 N ALA O 118 8.369 11.515 58.825 1.00 60.70 N +ATOM 27576 CA ALA O 118 8.351 11.839 57.420 1.00 63.35 C +ATOM 27577 C ALA O 118 7.121 12.663 57.054 1.00 95.39 C +ATOM 27578 O ALA O 118 5.990 12.359 57.475 1.00128.28 O +ATOM 27579 CB ALA O 118 8.386 10.581 56.605 1.00 46.50 C +ATOM 27580 N ALA O 119 7.336 13.620 56.160 1.00 88.79 N +ATOM 27581 CA ALA O 119 6.307 14.547 55.739 1.00 86.26 C +ATOM 27582 C ALA O 119 5.429 14.002 54.608 1.00 92.68 C +ATOM 27583 O ALA O 119 5.891 13.167 53.817 1.00 64.94 O +ATOM 27584 CB ALA O 119 6.960 15.841 55.297 1.00116.41 C +ATOM 27585 N ASN O 120 4.192 14.520 54.493 1.00103.78 N +ATOM 27586 CA ASN O 120 3.327 14.171 53.359 1.00 99.04 C +ATOM 27587 C ASN O 120 3.295 15.201 52.265 1.00 79.36 C +ATOM 27588 O ASN O 120 3.445 14.885 51.066 1.00101.99 O +ATOM 27589 CB ASN O 120 1.900 13.932 53.786 1.00100.96 C +ATOM 27590 CG ASN O 120 1.009 13.509 52.619 1.00128.88 C +ATOM 27591 OD1 ASN O 120 1.434 12.802 51.683 1.00 93.53 O +ATOM 27592 ND2 ASN O 120 -0.232 13.990 52.646 1.00175.23 N +ATOM 27593 N ILE O 121 3.138 16.444 52.658 1.00 72.14 N +ATOM 27594 CA ILE O 121 3.330 17.507 51.703 1.00120.51 C +ATOM 27595 C ILE O 121 4.649 18.216 52.032 1.00117.18 C +ATOM 27596 O ILE O 121 4.971 18.428 53.179 1.00108.44 O +ATOM 27597 CB ILE O 121 2.116 18.479 51.680 1.00152.38 C +ATOM 27598 CG1 ILE O 121 2.079 19.378 52.928 1.00152.19 C +ATOM 27599 CG2 ILE O 121 0.821 17.693 51.526 1.00147.12 C +ATOM 27600 CD1 ILE O 121 2.366 20.839 52.633 1.00157.68 C +ATOM 27601 N MET O 122 5.377 18.641 51.008 1.00108.39 N +ATOM 27602 CA MET O 122 6.420 19.610 51.227 1.00 91.38 C +ATOM 27603 C MET O 122 6.175 20.892 50.419 1.00 77.37 C +ATOM 27604 O MET O 122 5.575 20.859 49.345 1.00 64.57 O +ATOM 27605 CB MET O 122 7.752 18.970 50.897 1.00119.05 C +ATOM 27606 CG MET O 122 7.904 18.444 49.474 1.00108.74 C +ATOM 27607 SD MET O 122 9.641 18.522 48.995 1.00 99.81 S +ATOM 27608 CE MET O 122 9.534 19.103 47.334 1.00 88.25 C +ATOM 27609 N VAL O 123 6.506 22.027 51.016 1.00 62.50 N +ATOM 27610 CA VAL O 123 6.248 23.300 50.371 1.00 79.83 C +ATOM 27611 C VAL O 123 7.536 24.031 50.110 1.00 81.17 C +ATOM 27612 O VAL O 123 8.372 24.192 51.010 1.00 71.21 O +ATOM 27613 CB VAL O 123 5.367 24.226 51.220 1.00118.80 C +ATOM 27614 CG1 VAL O 123 5.731 24.140 52.695 1.00131.13 C +ATOM 27615 CG2 VAL O 123 5.457 25.678 50.725 1.00152.39 C +ATOM 27616 N GLU O 124 7.732 24.442 48.859 1.00 84.67 N +ATOM 27617 CA GLU O 124 8.917 25.225 48.492 1.00 91.33 C +ATOM 27618 C GLU O 124 8.504 26.417 47.692 1.00 70.71 C +ATOM 27619 O GLU O 124 7.373 26.554 47.327 1.00 50.44 O +ATOM 27620 CB GLU O 124 9.946 24.419 47.680 1.00118.08 C +ATOM 27621 CG GLU O 124 9.381 23.318 46.809 1.00126.98 C +ATOM 27622 CD GLU O 124 10.456 22.340 46.380 1.00144.10 C +ATOM 27623 OE1 GLU O 124 11.363 22.032 47.184 1.00166.57 O +ATOM 27624 OE2 GLU O 124 10.374 21.839 45.255 1.00163.63 O +ATOM 27625 N GLY O 125 9.451 27.318 47.495 1.00 91.15 N +ATOM 27626 CA GLY O 125 9.166 28.598 46.895 1.00 94.12 C +ATOM 27627 C GLY O 125 10.428 29.403 46.653 1.00 88.38 C +ATOM 27628 O GLY O 125 11.530 28.859 46.626 1.00 93.01 O +ATOM 27629 N SER O 126 10.266 30.699 46.458 1.00 75.10 N +ATOM 27630 CA SER O 126 11.376 31.517 46.011 1.00 71.29 C +ATOM 27631 C SER O 126 11.028 32.957 46.245 1.00 85.47 C +ATOM 27632 O SER O 126 9.868 33.349 46.156 1.00 92.99 O +ATOM 27633 CB SER O 126 11.672 31.335 44.510 1.00 61.74 C +ATOM 27634 OG SER O 126 11.383 30.018 44.051 1.00 59.63 O +ATOM 27635 N ILE O 127 12.039 33.765 46.520 1.00 95.28 N +ATOM 27636 CA ILE O 127 11.849 35.207 46.504 1.00 81.19 C +ATOM 27637 C ILE O 127 11.938 35.630 45.073 1.00 84.85 C +ATOM 27638 O ILE O 127 13.015 35.671 44.483 1.00135.33 O +ATOM 27639 CB ILE O 127 12.888 35.961 47.351 1.00 86.74 C +ATOM 27640 CG1 ILE O 127 12.695 35.658 48.861 1.00 84.66 C +ATOM 27641 CG2 ILE O 127 12.773 37.456 47.100 1.00 85.50 C +ATOM 27642 CD1 ILE O 127 13.971 35.711 49.691 1.00 53.84 C +ATOM 27643 N ILE O 128 10.784 35.865 44.485 1.00 88.37 N +ATOM 27644 CA ILE O 128 10.680 36.266 43.098 1.00103.39 C +ATOM 27645 C ILE O 128 10.685 37.783 43.076 1.00 94.69 C +ATOM 27646 O ILE O 128 9.695 38.434 43.437 1.00106.42 O +ATOM 27647 CB ILE O 128 9.289 35.989 42.509 1.00109.41 C +ATOM 27648 CG1 ILE O 128 8.676 34.597 42.695 1.00 91.78 C +ATOM 27649 CG2 ILE O 128 9.354 36.215 41.036 1.00132.39 C +ATOM 27650 CD1 ILE O 128 7.152 34.668 42.691 1.00 93.57 C +ATOM 27651 N GLY O 129 11.825 38.347 42.754 1.00 76.61 N +ATOM 27652 CA GLY O 129 11.877 39.776 42.500 1.00104.45 C +ATOM 27653 C GLY O 129 11.948 40.770 43.670 1.00117.55 C +ATOM 27654 O GLY O 129 11.308 40.620 44.721 1.00113.02 O +ATOM 27655 N TYR O 130 12.843 41.736 43.500 1.00115.12 N +ATOM 27656 CA TYR O 130 12.897 42.928 44.337 1.00 89.25 C +ATOM 27657 C TYR O 130 13.247 44.066 43.421 1.00 83.50 C +ATOM 27658 O TYR O 130 14.335 44.094 42.837 1.00 80.66 O +ATOM 27659 CB TYR O 130 13.972 42.801 45.417 1.00110.86 C +ATOM 27660 CG TYR O 130 14.194 44.049 46.227 1.00111.85 C +ATOM 27661 CD1 TYR O 130 14.788 45.194 45.658 1.00 97.88 C +ATOM 27662 CD2 TYR O 130 13.899 44.061 47.582 1.00109.48 C +ATOM 27663 CE1 TYR O 130 15.036 46.325 46.414 1.00101.65 C +ATOM 27664 CE2 TYR O 130 14.147 45.186 48.349 1.00127.50 C +ATOM 27665 CZ TYR O 130 14.705 46.319 47.760 1.00113.37 C +ATOM 27666 OH TYR O 130 14.891 47.426 48.552 1.00 99.38 O +ATOM 27667 N GLU O 131 12.253 44.859 43.087 1.00117.87 N +ATOM 27668 CA GLU O 131 12.500 46.030 42.255 1.00151.93 C +ATOM 27669 C GLU O 131 12.643 47.199 43.209 1.00153.55 C +ATOM 27670 O GLU O 131 12.016 47.207 44.268 1.00100.54 O +ATOM 27671 CB GLU O 131 11.355 46.228 41.256 1.00162.80 C +ATOM 27672 CG GLU O 131 11.575 47.321 40.222 1.00157.37 C +ATOM 27673 CD GLU O 131 12.319 46.858 38.979 1.00191.41 C +ATOM 27674 OE1 GLU O 131 12.222 45.656 38.619 1.00285.66 O +ATOM 27675 OE2 GLU O 131 12.968 47.708 38.329 1.00176.14 O +ATOM 27676 N SER O 132 13.481 48.165 42.842 1.00155.26 N +ATOM 27677 CA SER O 132 13.829 49.239 43.756 1.00151.62 C +ATOM 27678 C SER O 132 13.408 50.619 43.227 1.00159.09 C +ATOM 27679 O SER O 132 13.555 50.902 42.032 1.00166.99 O +ATOM 27680 CB SER O 132 15.329 49.201 44.045 1.00138.93 C +ATOM 27681 OG SER O 132 15.980 50.334 43.502 1.00113.98 O +ATOM 27682 N ASN O 133 12.920 51.474 44.131 1.00140.34 N +ATOM 27683 CA ASN O 133 12.310 52.757 43.756 1.00144.20 C +ATOM 27684 C ASN O 133 11.282 52.586 42.648 1.00150.22 C +ATOM 27685 O ASN O 133 11.383 53.186 41.576 1.00 94.49 O +ATOM 27686 CB ASN O 133 13.359 53.781 43.323 1.00134.04 C +ATOM 27687 CG ASN O 133 14.345 54.105 44.424 1.00127.61 C +ATOM 27688 OD1 ASN O 133 14.039 54.017 45.625 1.00 82.24 O +ATOM 27689 ND2 ASN O 133 15.552 54.472 44.019 1.00127.50 N +ATOM 27690 N VAL O 134 10.320 51.714 42.917 1.00175.74 N +ATOM 27691 CA VAL O 134 9.260 51.411 41.968 1.00151.75 C +ATOM 27692 C VAL O 134 8.430 52.673 41.850 1.00144.04 C +ATOM 27693 O VAL O 134 7.913 52.999 40.786 1.00114.38 O +ATOM 27694 CB VAL O 134 8.414 50.204 42.453 1.00160.97 C +ATOM 27695 CG1 VAL O 134 7.344 49.842 41.442 1.00139.05 C +ATOM 27696 CG2 VAL O 134 9.312 48.989 42.705 1.00221.85 C +ATOM 27697 N LYS O 135 8.298 53.378 42.971 1.00181.38 N +ATOM 27698 CA LYS O 135 7.796 54.749 42.945 1.00188.41 C +ATOM 27699 C LYS O 135 8.621 55.650 43.849 1.00180.23 C +ATOM 27700 O LYS O 135 9.295 55.188 44.787 1.00218.40 O +ATOM 27701 CB LYS O 135 6.331 54.809 43.391 1.00203.29 C +ATOM 27702 CG LYS O 135 5.379 54.052 42.482 1.00197.75 C +ATOM 27703 CD LYS O 135 3.972 54.067 43.049 1.00180.13 C +ATOM 27704 CE LYS O 135 3.009 53.301 42.171 1.00169.19 C +ATOM 27705 NZ LYS O 135 1.614 53.734 42.437 1.00162.55 N +ATOM 27706 N SER O 136 8.524 56.948 43.590 1.00130.64 N +ATOM 27707 CA SER O 136 9.234 57.930 44.378 1.00108.45 C +ATOM 27708 C SER O 136 8.653 59.301 44.169 1.00 80.66 C +ATOM 27709 O SER O 136 8.096 59.595 43.114 1.00 81.41 O +ATOM 27710 CB SER O 136 10.745 57.897 44.056 1.00133.43 C +ATOM 27711 OG SER O 136 11.239 59.165 43.647 1.00121.79 O +ATOM 27712 N GLY O 137 8.896 60.183 45.125 1.00 90.64 N +ATOM 27713 CA GLY O 137 8.509 61.592 44.975 1.00139.20 C +ATOM 27714 C GLY O 137 9.149 62.521 45.995 1.00165.03 C +ATOM 27715 O GLY O 137 9.841 62.064 46.908 1.00236.54 O +ATOM 27716 N GLY O 138 8.906 63.822 45.853 1.00133.65 N +ATOM 27717 CA GLY O 138 9.421 64.795 46.803 1.00130.69 C +ATOM 27718 C GLY O 138 8.755 66.141 46.696 1.00160.35 C +ATOM 27719 O GLY O 138 8.341 66.554 45.614 1.00189.01 O +ATOM 27720 N VAL O 139 8.581 66.796 47.841 1.00204.17 N +ATOM 27721 CA VAL O 139 7.986 68.133 47.891 1.00204.30 C +ATOM 27722 C VAL O 139 8.748 69.002 48.878 1.00213.15 C +ATOM 27723 O VAL O 139 8.915 68.635 50.046 1.00223.43 O +ATOM 27724 CB VAL O 139 6.504 68.103 48.318 1.00167.57 C +ATOM 27725 CG1 VAL O 139 5.982 69.519 48.479 1.00149.11 C +ATOM 27726 CG2 VAL O 139 5.666 67.333 47.305 1.00160.92 C +ATOM 27727 N GLY O 140 9.204 70.159 48.405 1.00212.10 N +ATOM 27728 CA GLY O 140 9.974 71.078 49.235 1.00224.93 C +ATOM 27729 C GLY O 140 9.788 72.539 48.877 1.00204.88 C +ATOM 27730 O GLY O 140 9.618 72.888 47.709 1.00192.73 O +ATOM 27731 N ALA O 141 9.820 73.396 49.893 1.00193.55 N +ATOM 27732 CA ALA O 141 9.685 74.833 49.687 1.00177.79 C +ATOM 27733 C ALA O 141 10.552 75.632 50.652 1.00173.17 C +ATOM 27734 O ALA O 141 10.708 75.273 51.820 1.00166.82 O +ATOM 27735 CB ALA O 141 8.229 75.251 49.806 1.00162.99 C +ATOM 27736 N ARG O 142 11.166 76.680 50.129 1.00175.67 N +ATOM 27737 CA ARG O 142 11.899 77.600 50.958 1.00176.95 C +ATOM 27738 C ARG O 142 11.419 79.006 50.648 1.00222.82 C +ATOM 27739 O ARG O 142 11.075 79.319 49.506 1.00258.73 O +ATOM 27740 CB ARG O 142 13.410 77.468 50.738 1.00167.85 C +ATOM 27741 CG ARG O 142 14.224 78.368 51.657 1.00166.12 C +ATOM 27742 CD ARG O 142 15.451 77.682 52.237 1.00164.80 C +ATOM 27743 NE ARG O 142 16.651 77.832 51.431 1.00145.87 N +ATOM 27744 CZ ARG O 142 17.713 77.035 51.507 1.00140.81 C +ATOM 27745 NH1 ARG O 142 17.688 75.934 52.250 1.00133.56 N +ATOM 27746 NH2 ARG O 142 18.784 77.302 50.771 1.00174.26 N +ATOM 27747 N TYR O 143 11.375 79.842 51.681 1.00242.69 N +ATOM 27748 CA TYR O 143 10.821 81.190 51.583 1.00231.35 C +ATOM 27749 C TYR O 143 11.770 82.240 52.178 1.00189.61 C +ATOM 27750 O TYR O 143 11.648 82.631 53.342 1.00141.43 O +ATOM 27751 CB TYR O 143 9.456 81.246 52.282 1.00240.08 C +ATOM 27752 CG TYR O 143 8.776 82.572 52.109 1.00256.27 C +ATOM 27753 CD1 TYR O 143 8.303 82.966 50.868 1.00253.22 C +ATOM 27754 CD2 TYR O 143 8.692 83.472 53.162 1.00251.43 C +ATOM 27755 CE1 TYR O 143 7.734 84.212 50.688 1.00242.42 C +ATOM 27756 CE2 TYR O 143 8.115 84.718 52.999 1.00238.68 C +ATOM 27757 CZ TYR O 143 7.639 85.083 51.758 1.00233.94 C +ATOM 27758 OH TYR O 143 7.070 86.318 51.580 1.00231.20 O +ATOM 27759 N GLY O 145 13.966 82.583 53.739 1.00163.70 N +ATOM 27760 CA GLY O 145 14.898 82.155 54.777 1.00147.15 C +ATOM 27761 C GLY O 145 14.561 80.824 55.436 1.00150.32 C +ATOM 27762 O GLY O 145 15.459 80.156 55.944 1.00171.50 O +ATOM 27763 N ILE O 146 13.288 80.417 55.394 1.00168.55 N +ATOM 27764 CA ILE O 146 12.807 79.217 56.111 1.00173.45 C +ATOM 27765 C ILE O 146 12.357 78.157 55.096 1.00188.00 C +ATOM 27766 O ILE O 146 11.707 78.487 54.105 1.00167.28 O +ATOM 27767 CB ILE O 146 11.626 79.546 57.068 1.00143.85 C +ATOM 27768 CG1 ILE O 146 11.855 80.901 57.756 1.00145.33 C +ATOM 27769 CG2 ILE O 146 11.446 78.444 58.106 1.00119.39 C +ATOM 27770 CD1 ILE O 146 11.161 82.065 57.082 1.00140.06 C +ATOM 27771 N GLY O 147 12.707 76.892 55.328 1.00202.39 N +ATOM 27772 CA GLY O 147 12.406 75.845 54.352 1.00192.65 C +ATOM 27773 C GLY O 147 12.197 74.452 54.913 1.00202.98 C +ATOM 27774 O GLY O 147 12.700 74.107 55.980 1.00233.06 O +ATOM 27775 N ALA O 148 11.456 73.642 54.172 1.00198.47 N +ATOM 27776 CA ALA O 148 11.293 72.237 54.511 1.00172.25 C +ATOM 27777 C ALA O 148 11.141 71.409 53.242 1.00172.69 C +ATOM 27778 O ALA O 148 10.923 71.952 52.150 1.00240.69 O +ATOM 27779 CB ALA O 148 10.101 72.048 55.446 1.00137.90 C +ATOM 27780 N ASP O 149 11.259 70.096 53.389 1.00138.77 N +ATOM 27781 CA ASP O 149 11.036 69.191 52.275 1.00144.43 C +ATOM 27782 C ASP O 149 10.849 67.761 52.765 1.00145.31 C +ATOM 27783 O ASP O 149 11.411 67.369 53.793 1.00178.62 O +ATOM 27784 CB ASP O 149 12.193 69.284 51.271 1.00133.03 C +ATOM 27785 CG ASP O 149 13.386 68.501 51.697 1.00141.69 C +ATOM 27786 OD1 ASP O 149 14.090 68.955 52.621 1.00159.46 O +ATOM 27787 OD2 ASP O 149 13.611 67.413 51.128 1.00159.92 O +ATOM 27788 N THR O 150 10.027 66.996 52.056 1.00146.75 N +ATOM 27789 CA THR O 150 10.024 65.552 52.241 1.00170.93 C +ATOM 27790 C THR O 150 10.348 64.863 50.924 1.00191.14 C +ATOM 27791 O THR O 150 10.123 65.416 49.844 1.00235.60 O +ATOM 27792 CB THR O 150 8.677 65.022 52.786 1.00148.25 C +ATOM 27793 OG1 THR O 150 7.627 65.363 51.881 1.00145.95 O +ATOM 27794 CG2 THR O 150 8.384 65.593 54.158 1.00128.33 C +ATOM 27795 N GLN O 151 10.888 63.656 51.028 1.00160.66 N +ATOM 27796 CA GLN O 151 11.111 62.799 49.886 1.00116.12 C +ATOM 27797 C GLN O 151 10.711 61.392 50.254 1.00108.24 C +ATOM 27798 O GLN O 151 10.878 60.978 51.383 1.00119.45 O +ATOM 27799 CB GLN O 151 12.575 62.849 49.517 1.00113.16 C +ATOM 27800 CG GLN O 151 12.970 64.163 48.889 1.00135.44 C +ATOM 27801 CD GLN O 151 14.450 64.424 49.006 1.00164.54 C +ATOM 27802 OE1 GLN O 151 15.253 63.512 48.824 1.00220.51 O +ATOM 27803 NE2 GLN O 151 14.825 65.666 49.299 1.00184.54 N +ATOM 27804 N TYR O 152 10.117 60.668 49.321 1.00124.51 N +ATOM 27805 CA TYR O 152 9.755 59.282 49.597 1.00144.10 C +ATOM 27806 C TYR O 152 10.108 58.360 48.442 1.00164.20 C +ATOM 27807 O TYR O 152 10.079 58.771 47.279 1.00214.08 O +ATOM 27808 CB TYR O 152 8.276 59.163 49.944 1.00114.40 C +ATOM 27809 CG TYR O 152 7.383 58.580 48.853 1.00118.27 C +ATOM 27810 CD1 TYR O 152 7.167 59.248 47.632 1.00 93.84 C +ATOM 27811 CD2 TYR O 152 6.684 57.405 49.077 1.00117.54 C +ATOM 27812 CE1 TYR O 152 6.348 58.714 46.644 1.00 69.03 C +ATOM 27813 CE2 TYR O 152 5.779 56.918 48.137 1.00109.73 C +ATOM 27814 CZ TYR O 152 5.625 57.571 46.918 1.00 84.87 C +ATOM 27815 OH TYR O 152 4.727 57.072 46.014 1.00 81.41 O +ATOM 27816 N GLN O 153 10.503 57.133 48.773 1.00137.31 N +ATOM 27817 CA GLN O 153 10.702 56.111 47.765 1.00118.05 C +ATOM 27818 C GLN O 153 10.047 54.822 48.236 1.00130.82 C +ATOM 27819 O GLN O 153 9.910 54.579 49.445 1.00153.41 O +ATOM 27820 CB GLN O 153 12.207 55.901 47.501 1.00118.91 C +ATOM 27821 CG GLN O 153 12.894 57.102 46.864 1.00115.37 C +ATOM 27822 CD GLN O 153 13.302 58.221 47.849 1.00116.50 C +ATOM 27823 OE1 GLN O 153 13.153 58.091 49.069 1.00106.42 O +ATOM 27824 NE2 GLN O 153 13.888 59.293 47.316 1.00102.81 N +ATOM 27825 N LEU O 154 9.672 53.973 47.288 1.00135.23 N +ATOM 27826 CA LEU O 154 9.199 52.640 47.648 1.00157.78 C +ATOM 27827 C LEU O 154 9.622 51.556 46.649 1.00132.29 C +ATOM 27828 O LEU O 154 9.615 51.782 45.434 1.00109.63 O +ATOM 27829 CB LEU O 154 7.675 52.644 47.850 1.00177.35 C +ATOM 27830 CG LEU O 154 6.825 52.787 46.579 1.00222.18 C +ATOM 27831 CD1 LEU O 154 6.393 51.430 46.043 1.00211.55 C +ATOM 27832 CD2 LEU O 154 5.623 53.672 46.862 1.00260.62 C +ATOM 27833 N ASP O 155 9.827 50.357 47.202 1.00114.11 N +ATOM 27834 CA ASP O 155 10.399 49.210 46.515 1.00 90.77 C +ATOM 27835 C ASP O 155 9.429 48.040 46.602 1.00102.64 C +ATOM 27836 O ASP O 155 8.488 48.048 47.416 1.00 91.22 O +ATOM 27837 CB ASP O 155 11.692 48.805 47.196 1.00108.20 C +ATOM 27838 CG ASP O 155 12.593 49.995 47.476 1.00162.92 C +ATOM 27839 OD1 ASP O 155 12.355 50.714 48.483 1.00222.92 O +ATOM 27840 OD2 ASP O 155 13.549 50.214 46.703 1.00185.31 O +ATOM 27841 N GLN O 156 9.603 47.051 45.726 1.00137.01 N +ATOM 27842 CA GLN O 156 8.678 45.893 45.685 1.00150.35 C +ATOM 27843 C GLN O 156 9.399 44.599 46.001 1.00138.50 C +ATOM 27844 O GLN O 156 10.614 44.516 45.866 1.00157.45 O +ATOM 27845 CB GLN O 156 8.002 45.770 44.315 1.00147.33 C +ATOM 27846 CG GLN O 156 6.849 44.781 44.275 1.00144.40 C +ATOM 27847 CD GLN O 156 5.897 45.035 43.113 1.00146.39 C +ATOM 27848 OE1 GLN O 156 6.169 45.855 42.227 1.00125.60 O +ATOM 27849 NE2 GLN O 156 4.764 44.338 43.121 1.00138.08 N +ATOM 27850 N ILE O 157 8.657 43.626 46.507 1.00107.76 N +ATOM 27851 CA ILE O 157 9.223 42.326 46.799 1.00113.38 C +ATOM 27852 C ILE O 157 8.105 41.306 46.598 1.00121.77 C +ATOM 27853 O ILE O 157 6.958 41.530 47.007 1.00146.19 O +ATOM 27854 CB ILE O 157 9.820 42.279 48.232 1.00126.96 C +ATOM 27855 CG1 ILE O 157 10.892 41.194 48.353 1.00115.78 C +ATOM 27856 CG2 ILE O 157 8.728 42.051 49.278 1.00145.25 C +ATOM 27857 CD1 ILE O 157 11.659 41.204 49.669 1.00 96.95 C +ATOM 27858 N ALA O 158 8.419 40.178 45.975 1.00103.25 N +ATOM 27859 CA ALA O 158 7.399 39.166 45.766 1.00 77.68 C +ATOM 27860 C ALA O 158 7.902 37.803 46.201 1.00 73.17 C +ATOM 27861 O ALA O 158 9.107 37.528 46.135 1.00104.89 O +ATOM 27862 CB ALA O 158 6.953 39.178 44.317 1.00 56.93 C +ATOM 27863 N VAL O 159 6.977 36.954 46.624 1.00 53.67 N +ATOM 27864 CA VAL O 159 7.324 35.634 47.085 1.00 74.89 C +ATOM 27865 C VAL O 159 6.391 34.537 46.562 1.00 91.25 C +ATOM 27866 O VAL O 159 5.170 34.703 46.525 1.00134.62 O +ATOM 27867 CB VAL O 159 7.294 35.602 48.602 1.00 96.79 C +ATOM 27868 CG1 VAL O 159 7.166 34.172 49.113 1.00122.42 C +ATOM 27869 CG2 VAL O 159 8.543 36.248 49.157 1.00109.34 C +ATOM 27870 N ASN O 160 6.989 33.465 46.027 1.00 95.62 N +ATOM 27871 CA ASN O 160 6.245 32.281 45.567 1.00 83.57 C +ATOM 27872 C ASN O 160 6.360 31.256 46.653 1.00 87.66 C +ATOM 27873 O ASN O 160 7.452 31.022 47.175 1.00 99.85 O +ATOM 27874 CB ASN O 160 6.856 31.732 44.261 1.00 82.49 C +ATOM 27875 CG ASN O 160 6.254 30.407 43.796 1.00 91.97 C +ATOM 27876 OD1 ASN O 160 6.010 29.491 44.569 1.00 78.25 O +ATOM 27877 ND2 ASN O 160 5.984 30.325 42.498 1.00112.56 N +ATOM 27878 N LEU O 161 5.219 30.733 47.070 1.00 84.26 N +ATOM 27879 CA LEU O 161 5.205 29.508 47.839 1.00 73.72 C +ATOM 27880 C LEU O 161 4.342 28.497 47.122 1.00 85.31 C +ATOM 27881 O LEU O 161 3.356 28.833 46.489 1.00102.15 O +ATOM 27882 CB LEU O 161 4.663 29.764 49.234 1.00 72.25 C +ATOM 27883 CG LEU O 161 5.493 30.680 50.117 1.00 73.35 C +ATOM 27884 CD1 LEU O 161 4.739 30.992 51.399 1.00 89.30 C +ATOM 27885 CD2 LEU O 161 6.821 30.018 50.423 1.00 91.02 C +ATOM 27886 N ARG O 162 4.682 27.231 47.246 1.00 96.44 N +ATOM 27887 CA ARG O 162 3.888 26.198 46.584 1.00 95.69 C +ATOM 27888 C ARG O 162 3.951 24.811 47.278 1.00 82.51 C +ATOM 27889 O ARG O 162 5.023 24.322 47.633 1.00 72.37 O +ATOM 27890 CB ARG O 162 4.254 26.115 45.094 1.00 85.97 C +ATOM 27891 CG ARG O 162 5.676 25.696 44.784 1.00113.29 C +ATOM 27892 CD ARG O 162 5.773 25.259 43.337 1.00107.27 C +ATOM 27893 NE ARG O 162 7.082 24.653 43.017 1.00146.42 N +ATOM 27894 CZ ARG O 162 8.205 25.318 42.737 1.00107.55 C +ATOM 27895 NH1 ARG O 162 8.208 26.642 42.774 1.00121.66 N +ATOM 27896 NH2 ARG O 162 9.323 24.648 42.444 1.00 72.29 N +ATOM 27897 N VAL O 163 2.775 24.220 47.467 1.00 72.63 N +ATOM 27898 CA VAL O 163 2.630 22.907 48.097 1.00 73.99 C +ATOM 27899 C VAL O 163 2.767 21.844 47.063 1.00 72.02 C +ATOM 27900 O VAL O 163 2.001 21.806 46.079 1.00121.63 O +ATOM 27901 CB VAL O 163 1.225 22.711 48.695 1.00 98.92 C +ATOM 27902 CG1 VAL O 163 1.094 21.304 49.283 1.00 72.56 C +ATOM 27903 CG2 VAL O 163 0.923 23.814 49.722 1.00130.37 C +ATOM 27904 N VAL O 164 3.713 20.960 47.290 1.00 66.75 N +ATOM 27905 CA VAL O 164 3.978 19.841 46.387 1.00 89.45 C +ATOM 27906 C VAL O 164 3.635 18.540 47.080 1.00 84.79 C +ATOM 27907 O VAL O 164 3.958 18.366 48.263 1.00112.63 O +ATOM 27908 CB VAL O 164 5.457 19.760 46.007 1.00118.55 C +ATOM 27909 CG1 VAL O 164 5.714 18.558 45.122 1.00127.89 C +ATOM 27910 CG2 VAL O 164 5.867 21.023 45.296 1.00137.61 C +ATOM 27911 N ASN O 165 2.948 17.657 46.355 1.00 63.73 N +ATOM 27912 CA ASN O 165 2.544 16.390 46.926 1.00 57.01 C +ATOM 27913 C ASN O 165 3.647 15.365 46.778 1.00 75.70 C +ATOM 27914 O ASN O 165 4.057 15.053 45.652 1.00110.82 O +ATOM 27915 CB ASN O 165 1.308 15.864 46.250 1.00 49.20 C +ATOM 27916 CG ASN O 165 0.785 14.638 46.944 1.00 55.57 C +ATOM 27917 OD1 ASN O 165 1.190 14.305 48.069 1.00 40.06 O +ATOM 27918 ND2 ASN O 165 -0.137 13.953 46.294 1.00 73.45 N +ATOM 27919 N VAL O 166 4.134 14.849 47.909 1.00 77.64 N +ATOM 27920 CA VAL O 166 5.272 13.925 47.932 1.00 70.06 C +ATOM 27921 C VAL O 166 4.946 12.668 47.198 1.00 75.40 C +ATOM 27922 O VAL O 166 5.759 12.165 46.443 1.00 80.27 O +ATOM 27923 CB VAL O 166 5.652 13.555 49.371 1.00 79.21 C +ATOM 27924 CG1 VAL O 166 6.355 12.212 49.443 1.00 65.27 C +ATOM 27925 CG2 VAL O 166 6.511 14.684 49.984 1.00128.41 C +ATOM 27926 N SER O 167 3.702 12.236 47.341 1.00 91.82 N +ATOM 27927 CA SER O 167 3.270 10.969 46.781 1.00100.28 C +ATOM 27928 C SER O 167 3.167 10.971 45.255 1.00102.67 C +ATOM 27929 O SER O 167 3.060 9.903 44.651 1.00101.95 O +ATOM 27930 CB SER O 167 1.937 10.578 47.401 1.00101.97 C +ATOM 27931 OG SER O 167 1.966 10.791 48.800 1.00150.25 O +ATOM 27932 N THR O 168 3.215 12.151 44.628 1.00 97.56 N +ATOM 27933 CA THR O 168 3.057 12.247 43.175 1.00 96.75 C +ATOM 27934 C THR O 168 4.055 13.203 42.500 1.00 77.93 C +ATOM 27935 O THR O 168 4.385 13.058 41.322 1.00 71.07 O +ATOM 27936 CB THR O 168 1.609 12.653 42.799 1.00103.89 C +ATOM 27937 OG1 THR O 168 1.223 13.830 43.531 1.00108.84 O +ATOM 27938 CG2 THR O 168 0.629 11.512 43.103 1.00101.36 C +ATOM 27939 N GLY O 169 4.375 14.281 43.175 1.00 59.47 N +ATOM 27940 CA GLY O 169 5.031 15.360 42.487 1.00 65.21 C +ATOM 27941 C GLY O 169 4.098 16.379 41.847 1.00 92.83 C +ATOM 27942 O GLY O 169 4.533 17.496 41.517 1.00163.92 O +ATOM 27943 N GLU O 170 2.797 16.101 41.834 1.00101.85 N +ATOM 27944 CA GLU O 170 1.801 17.140 41.569 1.00118.03 C +ATOM 27945 C GLU O 170 2.007 18.311 42.527 1.00112.79 C +ATOM 27946 O GLU O 170 2.041 18.145 43.727 1.00 66.98 O +ATOM 27947 CB GLU O 170 0.353 16.616 41.717 1.00143.40 C +ATOM 27948 CG GLU O 170 -0.116 15.734 40.559 1.00159.39 C +ATOM 27949 CD GLU O 170 -1.018 14.580 40.975 1.00160.26 C +ATOM 27950 OE1 GLU O 170 -1.127 14.311 42.190 1.00165.45 O +ATOM 27951 OE2 GLU O 170 -1.553 13.885 40.081 1.00153.09 O +ATOM 27952 N ILE O 171 2.121 19.514 41.984 1.00126.53 N +ATOM 27953 CA ILE O 171 1.960 20.698 42.793 1.00134.37 C +ATOM 27954 C ILE O 171 0.481 20.857 43.173 1.00145.94 C +ATOM 27955 O ILE O 171 -0.386 20.844 42.312 1.00134.64 O +ATOM 27956 CB ILE O 171 2.439 21.931 42.038 1.00118.58 C +ATOM 27957 CG1 ILE O 171 3.952 21.866 41.900 1.00103.18 C +ATOM 27958 CG2 ILE O 171 2.000 23.191 42.772 1.00145.34 C +ATOM 27959 CD1 ILE O 171 4.477 22.821 40.853 1.00125.46 C +ATOM 27960 N LEU O 172 0.195 20.947 44.468 1.00130.59 N +ATOM 27961 CA LEU O 172 -1.186 21.012 44.928 1.00105.83 C +ATOM 27962 C LEU O 172 -1.679 22.463 45.107 1.00112.37 C +ATOM 27963 O LEU O 172 -2.889 22.733 45.272 1.00 86.33 O +ATOM 27964 CB LEU O 172 -1.355 20.240 46.233 1.00110.10 C +ATOM 27965 CG LEU O 172 -1.231 18.704 46.091 1.00112.40 C +ATOM 27966 CD1 LEU O 172 -1.546 17.865 47.348 1.00124.69 C +ATOM 27967 CD2 LEU O 172 -1.973 18.162 44.884 1.00109.25 C +ATOM 27968 N SER O 173 -0.736 23.396 45.085 1.00 98.40 N +ATOM 27969 CA SER O 173 -1.061 24.799 45.205 1.00106.02 C +ATOM 27970 C SER O 173 0.162 25.658 44.907 1.00106.49 C +ATOM 27971 O SER O 173 1.223 25.467 45.491 1.00124.51 O +ATOM 27972 CB SER O 173 -1.565 25.106 46.623 1.00124.66 C +ATOM 27973 OG SER O 173 -1.560 26.507 46.871 1.00180.11 O +ATOM 27974 N SER O 174 -0.018 26.685 44.090 1.00114.56 N +ATOM 27975 CA SER O 174 0.985 27.749 43.961 1.00132.67 C +ATOM 27976 C SER O 174 0.359 29.093 44.304 1.00142.18 C +ATOM 27977 O SER O 174 -0.759 29.392 43.878 1.00192.02 O +ATOM 27978 CB SER O 174 1.546 27.789 42.531 1.00147.61 C +ATOM 27979 OG SER O 174 2.686 28.631 42.408 1.00148.94 O +ATOM 27980 N VAL O 175 1.085 29.909 45.062 1.00139.76 N +ATOM 27981 CA VAL O 175 0.622 31.258 45.411 1.00126.62 C +ATOM 27982 C VAL O 175 1.723 32.314 45.277 1.00124.10 C +ATOM 27983 O VAL O 175 2.905 32.041 45.535 1.00 95.40 O +ATOM 27984 CB VAL O 175 0.079 31.301 46.848 1.00136.79 C +ATOM 27985 CG1 VAL O 175 -1.130 30.392 46.980 1.00142.30 C +ATOM 27986 CG2 VAL O 175 1.137 30.883 47.848 1.00132.05 C +ATOM 27987 N ASN O 176 1.330 33.521 44.861 1.00120.43 N +ATOM 27988 CA ASN O 176 2.288 34.596 44.513 1.00122.26 C +ATOM 27989 C ASN O 176 2.004 35.899 45.261 1.00 82.79 C +ATOM 27990 O ASN O 176 1.205 36.683 44.804 1.00 92.65 O +ATOM 27991 CB ASN O 176 2.217 34.855 42.994 1.00118.45 C +ATOM 27992 CG ASN O 176 3.323 34.154 42.200 1.00124.53 C +ATOM 27993 OD1 ASN O 176 3.580 34.439 41.004 1.00127.69 O +ATOM 27994 ND2 ASN O 176 3.978 33.217 42.861 1.00111.95 N +ATOM 27995 N THR O 177 2.638 36.115 46.413 1.00 76.04 N +ATOM 27996 CA THR O 177 2.361 37.291 47.246 1.00 85.00 C +ATOM 27997 C THR O 177 3.363 38.404 46.957 1.00109.83 C +ATOM 27998 O THR O 177 4.454 38.148 46.443 1.00145.56 O +ATOM 27999 CB THR O 177 2.374 36.961 48.757 1.00 91.57 C +ATOM 28000 OG1 THR O 177 3.707 36.648 49.172 1.00105.77 O +ATOM 28001 CG2 THR O 177 1.472 35.774 49.068 1.00 99.21 C +ATOM 28002 N SER O 178 2.997 39.631 47.321 1.00128.70 N +ATOM 28003 CA SER O 178 3.827 40.811 47.049 1.00137.98 C +ATOM 28004 C SER O 178 3.673 41.863 48.142 1.00140.55 C +ATOM 28005 O SER O 178 2.659 41.929 48.830 1.00128.85 O +ATOM 28006 CB SER O 178 3.464 41.441 45.704 1.00125.95 C +ATOM 28007 OG SER O 178 4.033 42.741 45.581 1.00120.93 O +ATOM 28008 N LYS O 179 4.700 42.687 48.304 1.00138.98 N +ATOM 28009 CA LYS O 179 4.730 43.617 49.414 1.00123.49 C +ATOM 28010 C LYS O 179 5.632 44.798 49.070 1.00125.38 C +ATOM 28011 O LYS O 179 6.671 44.657 48.413 1.00100.47 O +ATOM 28012 CB LYS O 179 5.200 42.897 50.686 1.00114.41 C +ATOM 28013 CG LYS O 179 4.533 43.353 51.964 1.00 97.45 C +ATOM 28014 CD LYS O 179 5.370 44.420 52.632 1.00 98.87 C +ATOM 28015 CE LYS O 179 4.627 45.007 53.809 1.00125.87 C +ATOM 28016 NZ LYS O 179 5.270 46.258 54.292 1.00148.37 N +ATOM 28017 N THR O 180 5.228 45.965 49.548 1.00126.72 N +ATOM 28018 CA THR O 180 5.928 47.195 49.236 1.00138.86 C +ATOM 28019 C THR O 180 6.722 47.725 50.447 1.00144.41 C +ATOM 28020 O THR O 180 6.219 47.771 51.581 1.00 73.54 O +ATOM 28021 CB THR O 180 4.964 48.279 48.715 1.00154.26 C +ATOM 28022 OG1 THR O 180 5.537 49.572 48.946 1.00182.31 O +ATOM 28023 CG2 THR O 180 3.604 48.178 49.397 1.00139.48 C +ATOM 28024 N ILE O 181 7.983 48.086 50.197 1.00155.97 N +ATOM 28025 CA ILE O 181 8.855 48.624 51.242 1.00137.65 C +ATOM 28026 C ILE O 181 8.881 50.152 51.150 1.00114.88 C +ATOM 28027 O ILE O 181 9.370 50.710 50.157 1.00 96.17 O +ATOM 28028 CB ILE O 181 10.290 48.035 51.133 1.00129.16 C +ATOM 28029 CG1 ILE O 181 10.239 46.507 51.112 1.00139.81 C +ATOM 28030 CG2 ILE O 181 11.163 48.467 52.300 1.00124.88 C +ATOM 28031 CD1 ILE O 181 10.811 45.908 49.852 1.00171.90 C +ATOM 28032 N LEU O 182 8.401 50.811 52.206 1.00 98.13 N +ATOM 28033 CA LEU O 182 8.349 52.279 52.267 1.00113.85 C +ATOM 28034 C LEU O 182 9.574 52.970 52.897 1.00105.29 C +ATOM 28035 O LEU O 182 10.117 52.508 53.914 1.00112.75 O +ATOM 28036 CB LEU O 182 7.127 52.707 53.056 1.00123.35 C +ATOM 28037 CG LEU O 182 6.937 54.218 53.199 1.00154.62 C +ATOM 28038 CD1 LEU O 182 6.749 54.935 51.860 1.00167.93 C +ATOM 28039 CD2 LEU O 182 5.755 54.452 54.121 1.00174.22 C +ATOM 28040 N SER O 183 9.994 54.083 52.290 1.00 91.02 N +ATOM 28041 CA SER O 183 11.080 54.901 52.813 1.00104.45 C +ATOM 28042 C SER O 183 10.740 56.371 52.640 1.00139.35 C +ATOM 28043 O SER O 183 10.184 56.772 51.614 1.00168.77 O +ATOM 28044 CB SER O 183 12.402 54.593 52.095 1.00111.31 C +ATOM 28045 OG SER O 183 12.527 53.202 51.817 1.00144.94 O +ATOM 28046 N TYR O 184 11.075 57.182 53.640 1.00183.17 N +ATOM 28047 CA TYR O 184 10.875 58.627 53.538 1.00169.72 C +ATOM 28048 C TYR O 184 11.877 59.451 54.348 1.00171.55 C +ATOM 28049 O TYR O 184 12.414 59.005 55.368 1.00134.74 O +ATOM 28050 CB TYR O 184 9.432 59.002 53.894 1.00141.39 C +ATOM 28051 CG TYR O 184 9.019 58.577 55.286 1.00143.03 C +ATOM 28052 CD1 TYR O 184 9.278 59.383 56.386 1.00134.70 C +ATOM 28053 CD2 TYR O 184 8.350 57.371 55.497 1.00141.52 C +ATOM 28054 CE1 TYR O 184 8.871 59.003 57.649 1.00123.26 C +ATOM 28055 CE2 TYR O 184 7.942 56.980 56.762 1.00109.05 C +ATOM 28056 CZ TYR O 184 8.211 57.789 57.829 1.00110.76 C +ATOM 28057 OH TYR O 184 7.780 57.425 59.070 1.00106.05 O +ATOM 28058 N GLU O 185 12.078 60.681 53.883 1.00212.58 N +ATOM 28059 CA GLU O 185 13.015 61.630 54.479 1.00227.11 C +ATOM 28060 C GLU O 185 12.379 63.004 54.654 1.00217.82 C +ATOM 28061 O GLU O 185 12.089 63.686 53.678 1.00224.15 O +ATOM 28062 CB GLU O 185 14.282 61.797 53.639 1.00204.44 C +ATOM 28063 CG GLU O 185 14.854 60.524 53.051 1.00187.23 C +ATOM 28064 CD GLU O 185 16.209 60.777 52.421 1.00201.84 C +ATOM 28065 OE1 GLU O 185 16.659 61.954 52.411 1.00227.74 O +ATOM 28066 OE2 GLU O 185 16.832 59.803 51.959 1.00188.48 O +ATOM 28067 N VAL O 186 12.172 63.393 55.907 1.00162.01 N +ATOM 28068 CA VAL O 186 11.642 64.694 56.243 1.00142.75 C +ATOM 28069 C VAL O 186 12.780 65.605 56.698 1.00156.60 C +ATOM 28070 O VAL O 186 13.655 65.180 57.451 1.00216.93 O +ATOM 28071 CB VAL O 186 10.574 64.574 57.349 1.00131.67 C +ATOM 28072 CG1 VAL O 186 9.876 65.912 57.551 1.00160.92 C +ATOM 28073 CG2 VAL O 186 9.556 63.500 56.999 1.00118.00 C +ATOM 28074 N GLN O 187 12.751 66.862 56.263 1.00161.34 N +ATOM 28075 CA GLN O 187 13.817 67.808 56.584 1.00154.59 C +ATOM 28076 C GLN O 187 13.297 69.228 56.687 1.00196.25 C +ATOM 28077 O GLN O 187 12.478 69.657 55.870 1.00264.18 O +ATOM 28078 CB GLN O 187 14.876 67.763 55.487 1.00147.13 C +ATOM 28079 CG GLN O 187 15.925 66.688 55.642 1.00158.63 C +ATOM 28080 CD GLN O 187 16.594 66.366 54.320 1.00186.45 C +ATOM 28081 OE1 GLN O 187 16.881 67.269 53.528 1.00181.67 O +ATOM 28082 NE2 GLN O 187 16.860 65.078 54.074 1.00210.24 N +ATOM 28083 N ALA O 188 13.796 69.966 57.669 1.00208.09 N +ATOM 28084 CA ALA O 188 13.430 71.370 57.822 1.00217.06 C +ATOM 28085 C ALA O 188 14.637 72.189 58.261 1.00214.10 C +ATOM 28086 O ALA O 188 15.433 71.730 59.067 1.00243.75 O +ATOM 28087 CB ALA O 188 12.280 71.512 58.814 1.00200.22 C +ATOM 28088 N GLY O 189 14.772 73.396 57.721 1.00192.48 N +ATOM 28089 CA GLY O 189 15.883 74.270 58.070 1.00178.41 C +ATOM 28090 C GLY O 189 15.501 75.738 58.104 1.00192.41 C +ATOM 28091 O GLY O 189 14.745 76.217 57.258 1.00209.89 O +ATOM 28092 N VAL O 190 16.011 76.455 59.098 1.00208.79 N +ATOM 28093 CA VAL O 190 15.783 77.892 59.206 1.00201.97 C +ATOM 28094 C VAL O 190 17.110 78.630 58.998 1.00199.78 C +ATOM 28095 O VAL O 190 18.142 78.235 59.552 1.00214.86 O +ATOM 28096 CB VAL O 190 15.165 78.261 60.574 1.00182.54 C +ATOM 28097 CG1 VAL O 190 14.708 79.713 60.574 1.00168.34 C +ATOM 28098 CG2 VAL O 190 14.008 77.319 60.917 1.00141.66 C +ATOM 28099 N PHE O 191 17.083 79.697 58.198 1.00193.12 N +ATOM 28100 CA PHE O 191 18.316 80.371 57.779 1.00185.76 C +ATOM 28101 C PHE O 191 18.206 81.884 57.931 1.00174.81 C +ATOM 28102 O PHE O 191 17.207 82.476 57.527 1.00191.63 O +ATOM 28103 CB PHE O 191 18.637 80.008 56.324 1.00175.97 C +ATOM 28104 CG PHE O 191 20.075 80.209 55.948 1.00188.18 C +ATOM 28105 CD1 PHE O 191 20.592 81.486 55.773 1.00173.57 C +ATOM 28106 CD2 PHE O 191 20.919 79.120 55.762 1.00198.63 C +ATOM 28107 CE1 PHE O 191 21.924 81.677 55.426 1.00154.68 C +ATOM 28108 CE2 PHE O 191 22.255 79.306 55.429 1.00190.31 C +ATOM 28109 CZ PHE O 191 22.758 80.587 55.257 1.00143.50 C +ATOM 28110 N LEU O 200 22.496 83.074 61.517 1.00108.39 N +ATOM 28111 CA LEU O 200 21.607 82.067 62.100 1.00152.40 C +ATOM 28112 C LEU O 200 21.261 81.012 61.074 1.00193.97 C +ATOM 28113 O LEU O 200 20.492 81.269 60.136 1.00222.56 O +ATOM 28114 CB LEU O 200 20.286 82.638 62.675 1.00141.73 C +ATOM 28115 CG LEU O 200 19.267 81.561 63.127 1.00126.96 C +ATOM 28116 CD1 LEU O 200 19.315 81.384 64.643 1.00137.74 C +ATOM 28117 CD2 LEU O 200 17.839 81.832 62.653 1.00103.39 C +ATOM 28118 N GLU O 201 21.776 79.806 61.298 1.00215.27 N +ATOM 28119 CA GLU O 201 21.240 78.608 60.661 1.00203.06 C +ATOM 28120 C GLU O 201 20.771 77.602 61.713 1.00174.39 C +ATOM 28121 O GLU O 201 21.340 77.527 62.796 1.00125.90 O +ATOM 28122 CB GLU O 201 22.291 77.972 59.755 1.00188.96 C +ATOM 28123 CG GLU O 201 21.689 77.043 58.714 1.00184.04 C +ATOM 28124 CD GLU O 201 22.730 76.415 57.805 1.00194.56 C +ATOM 28125 OE1 GLU O 201 23.570 77.155 57.245 1.00190.03 O +ATOM 28126 OE2 GLU O 201 22.697 75.177 57.633 1.00208.12 O +ATOM 28127 N GLY O 202 19.731 76.839 61.383 1.00164.37 N +ATOM 28128 CA GLY O 202 19.276 75.732 62.221 1.00167.82 C +ATOM 28129 C GLY O 202 18.559 74.665 61.410 1.00174.34 C +ATOM 28130 O GLY O 202 17.639 74.970 60.655 1.00209.09 O +ATOM 28131 N GLU O 203 18.994 73.412 61.537 1.00164.15 N +ATOM 28132 CA GLU O 203 18.446 72.328 60.721 1.00165.23 C +ATOM 28133 C GLU O 203 18.020 71.105 61.525 1.00156.96 C +ATOM 28134 O GLU O 203 18.736 70.650 62.416 1.00193.00 O +ATOM 28135 CB GLU O 203 19.459 71.912 59.656 1.00175.25 C +ATOM 28136 CG GLU O 203 19.707 72.995 58.606 1.00194.87 C +ATOM 28137 CD GLU O 203 20.624 72.565 57.467 1.00195.11 C +ATOM 28138 OE1 GLU O 203 21.231 71.475 57.565 1.00166.99 O +ATOM 28139 OE2 GLU O 203 20.764 73.343 56.488 1.00205.57 O +ATOM 28140 N VAL O 204 16.852 70.571 61.178 1.00158.19 N +ATOM 28141 CA VAL O 204 16.355 69.300 61.705 1.00176.52 C +ATOM 28142 C VAL O 204 16.073 68.343 60.537 1.00186.32 C +ATOM 28143 O VAL O 204 15.502 68.743 59.522 1.00170.83 O +ATOM 28144 CB VAL O 204 15.079 69.512 62.564 1.00145.03 C +ATOM 28145 CG1 VAL O 204 14.336 68.202 62.813 1.00140.10 C +ATOM 28146 CG2 VAL O 204 15.449 70.172 63.882 1.00125.13 C +ATOM 28147 N GLY O 205 16.484 67.084 60.695 1.00174.14 N +ATOM 28148 CA GLY O 205 16.205 66.047 59.710 1.00143.53 C +ATOM 28149 C GLY O 205 15.766 64.730 60.339 1.00129.25 C +ATOM 28150 O GLY O 205 16.137 64.417 61.468 1.00129.75 O +ATOM 28151 N TYR O 206 14.964 63.960 59.604 1.00126.18 N +ATOM 28152 CA TYR O 206 14.566 62.608 60.012 1.00116.74 C +ATOM 28153 C TYR O 206 14.368 61.717 58.794 1.00130.20 C +ATOM 28154 O TYR O 206 13.841 62.165 57.782 1.00197.71 O +ATOM 28155 CB TYR O 206 13.261 62.641 60.806 1.00100.07 C +ATOM 28156 CG TYR O 206 12.743 61.262 61.197 1.00 91.60 C +ATOM 28157 CD1 TYR O 206 13.322 60.547 62.251 1.00 98.74 C +ATOM 28158 CD2 TYR O 206 11.653 60.699 60.557 1.00 75.87 C +ATOM 28159 CE1 TYR O 206 12.824 59.314 62.645 1.00 92.75 C +ATOM 28160 CE2 TYR O 206 11.144 59.474 60.952 1.00 84.82 C +ATOM 28161 CZ TYR O 206 11.733 58.775 61.991 1.00 86.87 C +ATOM 28162 OH TYR O 206 11.235 57.525 62.347 1.00 77.95 O +ATOM 28163 N THR O 207 14.767 60.452 58.890 1.00112.90 N +ATOM 28164 CA THR O 207 14.573 59.498 57.787 1.00 91.78 C +ATOM 28165 C THR O 207 14.080 58.153 58.327 1.00 72.53 C +ATOM 28166 O THR O 207 14.596 57.658 59.342 1.00 76.65 O +ATOM 28167 CB THR O 207 15.879 59.298 56.969 1.00 81.05 C +ATOM 28168 OG1 THR O 207 16.891 58.757 57.815 1.00 91.43 O +ATOM 28169 CG2 THR O 207 16.372 60.599 56.400 1.00 74.20 C +ATOM 28170 N SER O 208 13.109 57.548 57.648 1.00 66.88 N +ATOM 28171 CA SER O 208 12.619 56.222 58.053 1.00102.45 C +ATOM 28172 C SER O 208 12.515 55.238 56.889 1.00139.67 C +ATOM 28173 O SER O 208 11.886 55.532 55.879 1.00155.08 O +ATOM 28174 CB SER O 208 11.265 56.318 58.749 1.00 92.42 C +ATOM 28175 OG SER O 208 10.744 55.023 59.025 1.00 63.89 O +ATOM 28176 N ASN O 209 13.160 54.077 57.052 1.00133.18 N +ATOM 28177 CA ASN O 209 13.070 52.969 56.108 1.00 83.94 C +ATOM 28178 C ASN O 209 12.340 51.822 56.756 1.00 92.58 C +ATOM 28179 O ASN O 209 12.626 51.450 57.893 1.00108.92 O +ATOM 28180 CB ASN O 209 14.453 52.484 55.700 1.00 67.07 C +ATOM 28181 CG ASN O 209 15.174 53.464 54.843 1.00 68.71 C +ATOM 28182 OD1 ASN O 209 14.951 53.538 53.623 1.00111.15 O +ATOM 28183 ND2 ASN O 209 16.062 54.228 55.456 1.00 63.36 N +ATOM 28184 N GLU O 210 11.452 51.199 56.003 1.00117.34 N +ATOM 28185 CA GLU O 210 10.945 49.890 56.398 1.00146.64 C +ATOM 28186 C GLU O 210 12.091 48.859 56.316 1.00136.54 C +ATOM 28187 O GLU O 210 12.902 48.899 55.395 1.00147.92 O +ATOM 28188 CB GLU O 210 9.780 49.482 55.485 1.00159.32 C +ATOM 28189 CG GLU O 210 8.571 48.907 56.201 1.00134.68 C +ATOM 28190 CD GLU O 210 7.325 48.920 55.322 1.00117.50 C +ATOM 28191 OE1 GLU O 210 7.198 49.770 54.396 1.00 69.18 O +ATOM 28192 OE2 GLU O 210 6.455 48.069 55.588 1.00128.93 O +ATOM 28193 N PRO O 211 12.164 47.937 57.279 1.00105.25 N +ATOM 28194 CA PRO O 211 13.070 46.815 57.127 1.00115.55 C +ATOM 28195 C PRO O 211 12.607 45.837 56.027 1.00146.87 C +ATOM 28196 O PRO O 211 11.472 45.331 56.069 1.00182.67 O +ATOM 28197 CB PRO O 211 13.044 46.150 58.512 1.00 94.32 C +ATOM 28198 CG PRO O 211 12.473 47.166 59.418 1.00 96.04 C +ATOM 28199 CD PRO O 211 11.483 47.911 58.573 1.00 99.25 C +ATOM 28200 N VAL O 212 13.483 45.582 55.056 1.00123.78 N +ATOM 28201 CA VAL O 212 13.205 44.629 53.990 1.00103.08 C +ATOM 28202 C VAL O 212 13.021 43.237 54.594 1.00108.36 C +ATOM 28203 O VAL O 212 12.137 42.465 54.204 1.00129.23 O +ATOM 28204 CB VAL O 212 14.368 44.575 52.984 1.00117.17 C +ATOM 28205 CG1 VAL O 212 14.001 43.675 51.802 1.00146.32 C +ATOM 28206 CG2 VAL O 212 14.750 45.971 52.498 1.00101.68 C +ATOM 28207 N MET O 213 13.910 42.918 55.525 1.00109.21 N +ATOM 28208 CA MET O 213 13.761 41.823 56.475 1.00116.47 C +ATOM 28209 C MET O 213 12.297 41.541 56.903 1.00110.52 C +ATOM 28210 O MET O 213 11.792 40.406 56.839 1.00 93.57 O +ATOM 28211 CB MET O 213 14.608 42.244 57.683 1.00123.51 C +ATOM 28212 CG MET O 213 14.761 41.263 58.810 1.00155.56 C +ATOM 28213 SD MET O 213 15.815 42.043 60.044 1.00161.12 S +ATOM 28214 CE MET O 213 14.557 42.281 61.289 1.00188.74 C +ATOM 28215 N LEU O 214 11.627 42.595 57.338 1.00114.98 N +ATOM 28216 CA LEU O 214 10.357 42.472 58.028 1.00139.24 C +ATOM 28217 C LEU O 214 9.244 42.337 56.995 1.00146.68 C +ATOM 28218 O LEU O 214 8.191 41.752 57.259 1.00195.00 O +ATOM 28219 CB LEU O 214 10.143 43.702 58.929 1.00169.26 C +ATOM 28220 CG LEU O 214 9.583 43.506 60.342 1.00184.35 C +ATOM 28221 CD1 LEU O 214 10.464 42.606 61.198 1.00165.69 C +ATOM 28222 CD2 LEU O 214 9.406 44.863 61.015 1.00204.80 C +ATOM 28223 N CYS O 215 9.460 42.935 55.827 1.00126.88 N +ATOM 28224 CA CYS O 215 8.488 42.867 54.730 1.00129.67 C +ATOM 28225 C CYS O 215 8.476 41.464 54.138 1.00131.69 C +ATOM 28226 O CYS O 215 7.427 40.916 53.765 1.00 96.57 O +ATOM 28227 CB CYS O 215 8.857 43.874 53.638 1.00123.35 C +ATOM 28228 SG CYS O 215 8.726 45.586 54.157 1.00139.21 S +ATOM 28229 N LEU O 216 9.677 40.912 54.003 1.00144.60 N +ATOM 28230 CA LEU O 216 9.821 39.549 53.547 1.00130.84 C +ATOM 28231 C LEU O 216 9.027 38.647 54.487 1.00114.81 C +ATOM 28232 O LEU O 216 8.252 37.797 54.033 1.00113.95 O +ATOM 28233 CB LEU O 216 11.306 39.140 53.509 1.00140.94 C +ATOM 28234 CG LEU O 216 11.588 37.689 53.093 1.00122.14 C +ATOM 28235 CD1 LEU O 216 10.997 37.357 51.725 1.00124.10 C +ATOM 28236 CD2 LEU O 216 13.075 37.405 53.100 1.00 95.69 C +ATOM 28237 N MET O 217 9.223 38.841 55.791 1.00 94.40 N +ATOM 28238 CA MET O 217 8.611 37.969 56.776 1.00 93.90 C +ATOM 28239 C MET O 217 7.084 38.074 56.684 1.00122.92 C +ATOM 28240 O MET O 217 6.384 37.059 56.619 1.00121.34 O +ATOM 28241 CB MET O 217 9.100 38.319 58.179 1.00 83.16 C +ATOM 28242 CG MET O 217 9.401 37.091 59.024 1.00100.84 C +ATOM 28243 SD MET O 217 7.910 36.157 59.473 1.00157.59 S +ATOM 28244 CE MET O 217 8.593 34.662 60.203 1.00141.57 C +ATOM 28245 N SER O 218 6.585 39.308 56.612 1.00133.74 N +ATOM 28246 CA SER O 218 5.156 39.569 56.469 1.00113.14 C +ATOM 28247 C SER O 218 4.563 38.849 55.255 1.00131.91 C +ATOM 28248 O SER O 218 3.538 38.154 55.355 1.00137.48 O +ATOM 28249 CB SER O 218 4.917 41.068 56.326 1.00117.57 C +ATOM 28250 OG SER O 218 3.530 41.376 56.423 1.00186.10 O +ATOM 28251 N ALA O 219 5.200 39.026 54.102 1.00141.88 N +ATOM 28252 CA ALA O 219 4.687 38.463 52.854 1.00139.27 C +ATOM 28253 C ALA O 219 4.657 36.916 52.883 1.00124.55 C +ATOM 28254 O ALA O 219 3.758 36.277 52.324 1.00 82.88 O +ATOM 28255 CB ALA O 219 5.522 38.973 51.690 1.00136.86 C +ATOM 28256 N ILE O 220 5.636 36.318 53.557 1.00123.93 N +ATOM 28257 CA ILE O 220 5.696 34.863 53.666 1.00104.92 C +ATOM 28258 C ILE O 220 4.523 34.360 54.512 1.00116.21 C +ATOM 28259 O ILE O 220 3.901 33.339 54.196 1.00 73.00 O +ATOM 28260 CB ILE O 220 7.055 34.390 54.245 1.00 82.66 C +ATOM 28261 CG1 ILE O 220 8.155 34.633 53.208 1.00 74.93 C +ATOM 28262 CG2 ILE O 220 6.992 32.912 54.644 1.00 67.49 C +ATOM 28263 CD1 ILE O 220 9.550 34.574 53.776 1.00 96.62 C +ATOM 28264 N GLU O 221 4.230 35.069 55.598 1.00133.04 N +ATOM 28265 CA GLU O 221 3.097 34.711 56.457 1.00142.63 C +ATOM 28266 C GLU O 221 1.806 34.713 55.637 1.00135.61 C +ATOM 28267 O GLU O 221 1.032 33.749 55.661 1.00115.12 O +ATOM 28268 CB GLU O 221 2.995 35.695 57.633 1.00156.62 C +ATOM 28269 CG GLU O 221 4.050 35.488 58.711 1.00178.76 C +ATOM 28270 CD GLU O 221 4.199 36.679 59.654 1.00174.25 C +ATOM 28271 OE1 GLU O 221 4.126 37.851 59.193 1.00118.68 O +ATOM 28272 OE2 GLU O 221 4.501 36.413 60.841 1.00145.17 O +ATOM 28273 N THR O 222 1.594 35.819 54.924 1.00119.42 N +ATOM 28274 CA THR O 222 0.433 36.001 54.055 1.00100.88 C +ATOM 28275 C THR O 222 0.300 34.833 53.090 1.00109.35 C +ATOM 28276 O THR O 222 -0.791 34.279 52.927 1.00113.27 O +ATOM 28277 CB THR O 222 0.583 37.296 53.238 1.00 96.30 C +ATOM 28278 OG1 THR O 222 0.415 38.439 54.101 1.00 94.10 O +ATOM 28279 CG2 THR O 222 -0.406 37.337 52.044 1.00 80.02 C +ATOM 28280 N GLY O 223 1.413 34.480 52.446 1.00105.35 N +ATOM 28281 CA GLY O 223 1.462 33.327 51.551 1.00 92.56 C +ATOM 28282 C GLY O 223 1.046 32.030 52.224 1.00 91.87 C +ATOM 28283 O GLY O 223 0.309 31.218 51.634 1.00 79.88 O +ATOM 28284 N VAL O 224 1.453 31.853 53.484 1.00 75.48 N +ATOM 28285 CA VAL O 224 1.089 30.647 54.217 1.00 95.82 C +ATOM 28286 C VAL O 224 -0.428 30.591 54.432 1.00108.85 C +ATOM 28287 O VAL O 224 -1.057 29.533 54.273 1.00 85.22 O +ATOM 28288 CB VAL O 224 1.796 30.564 55.581 1.00100.89 C +ATOM 28289 CG1 VAL O 224 1.251 29.385 56.388 1.00109.70 C +ATOM 28290 CG2 VAL O 224 3.293 30.431 55.394 1.00 87.74 C +ATOM 28291 N ILE O 225 -1.020 31.736 54.774 1.00115.34 N +ATOM 28292 CA ILE O 225 -2.472 31.805 54.951 1.00136.34 C +ATOM 28293 C ILE O 225 -3.209 31.439 53.661 1.00136.38 C +ATOM 28294 O ILE O 225 -4.052 30.540 53.677 1.00111.21 O +ATOM 28295 CB ILE O 225 -2.934 33.191 55.421 1.00160.18 C +ATOM 28296 CG1 ILE O 225 -2.440 33.457 56.843 1.00178.26 C +ATOM 28297 CG2 ILE O 225 -4.451 33.273 55.397 1.00168.75 C +ATOM 28298 CD1 ILE O 225 -2.471 34.920 57.235 1.00190.14 C +ATOM 28299 N PHE O 226 -2.850 32.093 52.550 1.00130.42 N +ATOM 28300 CA PHE O 226 -3.432 31.771 51.243 1.00123.73 C +ATOM 28301 C PHE O 226 -3.285 30.280 50.888 1.00128.63 C +ATOM 28302 O PHE O 226 -4.163 29.703 50.239 1.00122.67 O +ATOM 28303 CB PHE O 226 -2.819 32.626 50.126 1.00120.50 C +ATOM 28304 CG PHE O 226 -3.376 34.037 50.040 1.00124.32 C +ATOM 28305 CD1 PHE O 226 -4.722 34.264 49.781 1.00 97.44 C +ATOM 28306 CD2 PHE O 226 -2.512 35.135 50.101 1.00134.42 C +ATOM 28307 CE1 PHE O 226 -5.209 35.549 49.684 1.00 90.11 C +ATOM 28308 CE2 PHE O 226 -2.985 36.423 49.946 1.00105.38 C +ATOM 28309 CZ PHE O 226 -4.342 36.631 49.767 1.00104.44 C +ATOM 28310 N LEU O 227 -2.183 29.660 51.308 1.00128.29 N +ATOM 28311 CA LEU O 227 -1.986 28.219 51.090 1.00125.57 C +ATOM 28312 C LEU O 227 -2.989 27.418 51.861 1.00119.45 C +ATOM 28313 O LEU O 227 -3.533 26.447 51.336 1.00178.78 O +ATOM 28314 CB LEU O 227 -0.607 27.735 51.544 1.00124.51 C +ATOM 28315 CG LEU O 227 0.351 27.189 50.489 1.00123.47 C +ATOM 28316 CD1 LEU O 227 0.057 27.880 49.205 1.00125.36 C +ATOM 28317 CD2 LEU O 227 1.851 27.243 50.763 1.00119.34 C +ATOM 28318 N ILE O 228 -3.161 27.759 53.135 1.00115.49 N +ATOM 28319 CA ILE O 228 -4.051 26.997 54.007 1.00132.51 C +ATOM 28320 C ILE O 228 -5.478 27.127 53.491 1.00149.81 C +ATOM 28321 O ILE O 228 -6.191 26.129 53.354 1.00152.34 O +ATOM 28322 CB ILE O 228 -4.004 27.469 55.476 1.00114.24 C +ATOM 28323 CG1 ILE O 228 -2.623 27.229 56.079 1.00106.92 C +ATOM 28324 CG2 ILE O 228 -5.031 26.713 56.301 1.00 95.84 C +ATOM 28325 CD1 ILE O 228 -2.367 27.978 57.367 1.00101.38 C +ATOM 28326 N ASN O 229 -5.876 28.356 53.178 1.00140.91 N +ATOM 28327 CA ASN O 229 -7.224 28.624 52.686 1.00145.38 C +ATOM 28328 C ASN O 229 -7.483 27.897 51.372 1.00124.72 C +ATOM 28329 O ASN O 229 -8.520 27.246 51.211 1.00121.81 O +ATOM 28330 CB ASN O 229 -7.421 30.129 52.496 1.00164.35 C +ATOM 28331 CG ASN O 229 -8.877 30.518 52.371 1.00164.08 C +ATOM 28332 OD1 ASN O 229 -9.773 29.813 52.847 1.00157.93 O +ATOM 28333 ND2 ASN O 229 -9.121 31.665 51.755 1.00170.08 N +ATOM 28334 N ASP O 230 -6.503 27.959 50.472 1.00102.86 N +ATOM 28335 CA ASP O 230 -6.562 27.231 49.207 1.00113.74 C +ATOM 28336 C ASP O 230 -6.702 25.713 49.427 1.00112.42 C +ATOM 28337 O ASP O 230 -7.497 25.045 48.758 1.00106.06 O +ATOM 28338 CB ASP O 230 -5.310 27.516 48.367 1.00111.65 C +ATOM 28339 CG ASP O 230 -5.390 26.928 46.968 1.00119.93 C +ATOM 28340 OD1 ASP O 230 -6.175 27.454 46.157 1.00180.29 O +ATOM 28341 OD2 ASP O 230 -4.737 25.910 46.684 1.00108.40 O +ATOM 28342 N GLY O 231 -5.959 25.182 50.391 1.00125.68 N +ATOM 28343 CA GLY O 231 -6.016 23.757 50.705 1.00136.58 C +ATOM 28344 C GLY O 231 -7.339 23.339 51.333 1.00135.94 C +ATOM 28345 O GLY O 231 -7.848 22.238 51.054 1.00142.64 O +ATOM 28346 N ILE O 232 -7.928 24.242 52.121 1.00116.54 N +ATOM 28347 CA ILE O 232 -9.270 24.026 52.668 1.00127.84 C +ATOM 28348 C ILE O 232 -10.309 23.898 51.552 1.00144.08 C +ATOM 28349 O ILE O 232 -11.068 22.926 51.517 1.00123.00 O +ATOM 28350 CB ILE O 232 -9.689 25.164 53.621 1.00135.48 C +ATOM 28351 CG1 ILE O 232 -8.898 25.056 54.928 1.00149.91 C +ATOM 28352 CG2 ILE O 232 -11.197 25.131 53.897 1.00135.07 C +ATOM 28353 CD1 ILE O 232 -8.902 26.323 55.753 1.00164.69 C +ATOM 28354 N ASP O 233 -10.307 24.863 50.630 1.00170.25 N +ATOM 28355 CA ASP O 233 -11.184 24.834 49.447 1.00155.74 C +ATOM 28356 C ASP O 233 -11.024 23.542 48.635 1.00170.44 C +ATOM 28357 O ASP O 233 -12.002 22.879 48.315 1.00187.67 O +ATOM 28358 CB ASP O 233 -10.900 26.035 48.529 1.00131.15 C +ATOM 28359 CG ASP O 233 -11.209 27.374 49.186 1.00118.70 C +ATOM 28360 OD1 ASP O 233 -11.506 27.399 50.402 1.00119.91 O +ATOM 28361 OD2 ASP O 233 -11.205 28.399 48.466 1.00120.87 O +ATOM 28362 N ARG O 234 -9.783 23.170 48.334 1.00181.68 N +ATOM 28363 CA ARG O 234 -9.511 22.030 47.454 1.00155.10 C +ATOM 28364 C ARG O 234 -9.586 20.664 48.146 1.00138.39 C +ATOM 28365 O ARG O 234 -9.371 19.631 47.509 1.00154.63 O +ATOM 28366 CB ARG O 234 -8.148 22.216 46.790 1.00166.77 C +ATOM 28367 CG ARG O 234 -8.185 23.293 45.730 1.00134.23 C +ATOM 28368 CD ARG O 234 -6.818 23.860 45.424 1.00137.16 C +ATOM 28369 NE ARG O 234 -7.007 24.908 44.422 1.00128.98 N +ATOM 28370 CZ ARG O 234 -6.453 24.915 43.212 1.00108.54 C +ATOM 28371 NH1 ARG O 234 -5.575 23.981 42.897 1.00126.14 N +ATOM 28372 NH2 ARG O 234 -6.719 25.892 42.363 1.00 80.95 N +ATOM 28373 N GLY O 235 -9.846 20.656 49.452 1.00119.17 N +ATOM 28374 CA GLY O 235 -10.007 19.411 50.197 1.00120.56 C +ATOM 28375 C GLY O 235 -8.703 18.703 50.513 1.00124.93 C +ATOM 28376 O GLY O 235 -8.658 17.466 50.554 1.00130.05 O +ATOM 28377 N LEU O 236 -7.624 19.465 50.695 1.00119.18 N +ATOM 28378 CA LEU O 236 -6.380 18.882 51.209 1.00130.27 C +ATOM 28379 C LEU O 236 -6.571 18.571 52.691 1.00131.44 C +ATOM 28380 O LEU O 236 -6.230 17.485 53.160 1.00105.37 O +ATOM 28381 CB LEU O 236 -5.174 19.821 51.009 1.00144.44 C +ATOM 28382 CG LEU O 236 -4.456 19.808 49.646 1.00141.61 C +ATOM 28383 CD1 LEU O 236 -5.237 20.603 48.616 1.00104.80 C +ATOM 28384 CD2 LEU O 236 -3.045 20.378 49.788 1.00167.23 C +ATOM 28385 N TRP O 237 -7.087 19.549 53.429 1.00148.63 N +ATOM 28386 CA TRP O 237 -7.268 19.417 54.878 1.00160.42 C +ATOM 28387 C TRP O 237 -8.600 20.034 55.296 1.00168.04 C +ATOM 28388 O TRP O 237 -9.214 20.786 54.522 1.00182.93 O +ATOM 28389 CB TRP O 237 -6.098 20.064 55.628 1.00148.69 C +ATOM 28390 CG TRP O 237 -5.536 21.259 54.912 1.00164.86 C +ATOM 28391 CD1 TRP O 237 -6.167 22.448 54.691 1.00177.34 C +ATOM 28392 CD2 TRP O 237 -4.241 21.375 54.304 1.00147.42 C +ATOM 28393 NE1 TRP O 237 -5.348 23.298 53.987 1.00148.97 N +ATOM 28394 CE2 TRP O 237 -4.156 22.669 53.746 1.00133.56 C +ATOM 28395 CE3 TRP O 237 -3.143 20.521 54.196 1.00139.75 C +ATOM 28396 CZ2 TRP O 237 -3.027 23.121 53.079 1.00116.58 C +ATOM 28397 CZ3 TRP O 237 -2.018 20.980 53.532 1.00142.76 C +ATOM 28398 CH2 TRP O 237 -1.967 22.276 52.994 1.00127.73 C +ATOM 28399 N ASP O 238 -9.042 19.714 56.512 1.00171.28 N +ATOM 28400 CA ASP O 238 -10.376 20.108 56.979 1.00204.81 C +ATOM 28401 C ASP O 238 -10.367 20.801 58.344 1.00209.75 C +ATOM 28402 O ASP O 238 -9.540 20.487 59.212 1.00159.60 O +ATOM 28403 CB ASP O 238 -11.306 18.896 57.043 1.00190.89 C +ATOM 28404 CG ASP O 238 -11.413 18.174 55.718 1.00160.78 C +ATOM 28405 OD1 ASP O 238 -10.487 17.398 55.405 1.00138.18 O +ATOM 28406 OD2 ASP O 238 -12.412 18.383 54.991 1.00151.80 O +ATOM 28407 N LEU O 239 -11.325 21.714 58.533 1.00185.16 N +ATOM 28408 CA LEU O 239 -11.445 22.474 59.770 1.00151.38 C +ATOM 28409 C LEU O 239 -12.059 21.615 60.859 1.00137.87 C +ATOM 28410 O LEU O 239 -12.924 20.778 60.597 1.00139.44 O +ATOM 28411 CB LEU O 239 -12.308 23.721 59.560 1.00151.37 C +ATOM 28412 CG LEU O 239 -11.713 24.933 58.848 1.00182.72 C +ATOM 28413 CD1 LEU O 239 -12.697 26.096 58.850 1.00205.68 C +ATOM 28414 CD2 LEU O 239 -10.415 25.361 59.505 1.00202.40 C +ATOM 28415 N GLN O 240 -11.600 21.825 62.088 1.00137.61 N +ATOM 28416 CA GLN O 240 -12.242 21.232 63.263 1.00119.32 C +ATOM 28417 C GLN O 240 -13.730 21.581 63.299 1.00137.77 C +ATOM 28418 O GLN O 240 -14.587 20.701 63.320 1.00125.38 O +ATOM 28419 CB GLN O 240 -11.560 21.730 64.542 1.00108.73 C +ATOM 28420 CG GLN O 240 -12.028 21.015 65.802 1.00106.99 C +ATOM 28421 CD GLN O 240 -11.649 19.550 65.803 1.00103.74 C +ATOM 28422 OE1 GLN O 240 -10.504 19.192 66.114 1.00130.48 O +ATOM 28423 NE2 GLN O 240 -12.585 18.695 65.412 1.00102.72 N +ATOM 28424 N ASN O 241 -14.012 22.880 63.263 1.00165.11 N +ATOM 28425 CA ASN O 241 -15.377 23.396 63.258 1.00153.85 C +ATOM 28426 C ASN O 241 -15.773 23.894 61.884 1.00166.71 C +ATOM 28427 O ASN O 241 -15.268 24.929 61.413 1.00185.81 O +ATOM 28428 CB ASN O 241 -15.496 24.550 64.243 1.00153.09 C +ATOM 28429 CG ASN O 241 -16.126 24.128 65.541 1.00162.36 C +ATOM 28430 OD1 ASN O 241 -17.298 24.404 65.778 1.00185.33 O +ATOM 28431 ND2 ASN O 241 -15.356 23.452 66.394 1.00169.79 N +ATOM 28432 N LYS O 242 -16.692 23.174 61.252 1.00149.60 N +ATOM 28433 CA LYS O 242 -17.140 23.537 59.915 1.00168.89 C +ATOM 28434 C LYS O 242 -17.878 24.869 59.976 1.00165.56 C +ATOM 28435 O LYS O 242 -17.915 25.623 58.988 1.00145.67 O +ATOM 28436 CB LYS O 242 -18.026 22.431 59.325 1.00166.76 C +ATOM 28437 CG LYS O 242 -17.417 21.034 59.423 1.00163.25 C +ATOM 28438 CD LYS O 242 -17.352 20.334 58.071 1.00163.79 C +ATOM 28439 CE LYS O 242 -15.987 19.697 57.845 1.00155.16 C +ATOM 28440 NZ LYS O 242 -15.939 18.875 56.609 1.00150.41 N +ATOM 28441 N ALA O 243 -18.423 25.151 61.163 1.00169.58 N +ATOM 28442 CA ALA O 243 -19.067 26.425 61.473 1.00190.19 C +ATOM 28443 C ALA O 243 -18.085 27.588 61.372 1.00214.85 C +ATOM 28444 O ALA O 243 -18.508 28.746 61.258 1.00266.09 O +ATOM 28445 CB ALA O 243 -19.680 26.382 62.870 1.00156.19 C +ATOM 28446 N GLU O 244 -16.786 27.291 61.427 1.00193.35 N +ATOM 28447 CA GLU O 244 -15.783 28.348 61.401 1.00171.80 C +ATOM 28448 C GLU O 244 -15.292 28.638 59.997 1.00145.69 C +ATOM 28449 O GLU O 244 -14.308 29.351 59.837 1.00155.06 O +ATOM 28450 CB GLU O 244 -14.602 28.002 62.311 1.00172.80 C +ATOM 28451 CG GLU O 244 -14.910 28.115 63.796 1.00176.85 C +ATOM 28452 CD GLU O 244 -13.662 28.026 64.661 1.00166.55 C +ATOM 28453 OE1 GLU O 244 -13.149 26.902 64.860 1.00146.43 O +ATOM 28454 OE2 GLU O 244 -13.213 29.082 65.164 1.00150.20 O +ATOM 28455 N ARG O 245 -15.965 28.095 58.985 1.00135.60 N +ATOM 28456 CA ARG O 245 -15.630 28.421 57.595 1.00175.05 C +ATOM 28457 C ARG O 245 -15.700 29.917 57.299 1.00178.81 C +ATOM 28458 O ARG O 245 -14.905 30.436 56.511 1.00143.50 O +ATOM 28459 CB ARG O 245 -16.524 27.689 56.606 1.00188.06 C +ATOM 28460 CG ARG O 245 -16.085 27.858 55.146 1.00194.11 C +ATOM 28461 CD ARG O 245 -16.934 27.031 54.163 1.00195.65 C +ATOM 28462 NE ARG O 245 -16.282 25.769 53.802 1.00191.22 N +ATOM 28463 CZ ARG O 245 -15.205 25.668 53.021 1.00189.37 C +ATOM 28464 NH1 ARG O 245 -14.626 26.748 52.528 1.00173.02 N +ATOM 28465 NH2 ARG O 245 -14.682 24.479 52.749 1.00196.22 N +ATOM 28466 N GLN O 246 -16.664 30.604 57.907 1.00194.57 N +ATOM 28467 CA GLN O 246 -16.865 32.028 57.631 1.00194.12 C +ATOM 28468 C GLN O 246 -16.108 32.913 58.613 1.00174.14 C +ATOM 28469 O GLN O 246 -16.455 34.073 58.814 1.00184.35 O +ATOM 28470 CB GLN O 246 -18.358 32.363 57.632 1.00198.26 C +ATOM 28471 CG GLN O 246 -19.117 31.662 56.509 1.00183.32 C +ATOM 28472 CD GLN O 246 -18.889 32.257 55.125 1.00186.65 C +ATOM 28473 OE1 GLN O 246 -17.755 32.500 54.714 1.00200.15 O +ATOM 28474 NE2 GLN O 246 -19.972 32.443 54.378 1.00204.75 N +ATOM 28475 N ASN O 247 -15.090 32.339 59.246 1.00162.61 N +ATOM 28476 CA ASN O 247 -14.116 33.096 60.030 1.00163.23 C +ATOM 28477 C ASN O 247 -13.719 34.404 59.342 1.00167.44 C +ATOM 28478 O ASN O 247 -13.497 34.423 58.125 1.00185.68 O +ATOM 28479 CB ASN O 247 -12.863 32.241 60.232 1.00179.60 C +ATOM 28480 CG ASN O 247 -12.093 32.624 61.466 1.00160.06 C +ATOM 28481 OD1 ASN O 247 -10.993 33.181 61.385 1.00159.51 O +ATOM 28482 ND2 ASN O 247 -12.649 32.292 62.621 1.00150.78 N +ATOM 28483 N ASP O 248 -13.600 35.478 60.123 1.00165.24 N +ATOM 28484 CA ASP O 248 -13.282 36.812 59.579 1.00194.99 C +ATOM 28485 C ASP O 248 -12.025 36.782 58.704 1.00221.88 C +ATOM 28486 O ASP O 248 -11.986 37.352 57.601 1.00230.60 O +ATOM 28487 CB ASP O 248 -13.055 37.820 60.715 1.00191.46 C +ATOM 28488 CG ASP O 248 -14.332 38.190 61.443 1.00196.42 C +ATOM 28489 OD1 ASP O 248 -15.388 38.332 60.785 1.00206.78 O +ATOM 28490 OD2 ASP O 248 -14.271 38.368 62.678 1.00185.64 O +ATOM 28491 N ILE O 249 -10.989 36.133 59.225 1.00214.36 N +ATOM 28492 CA ILE O 249 -9.696 36.077 58.561 1.00191.65 C +ATOM 28493 C ILE O 249 -9.808 35.275 57.260 1.00176.35 C +ATOM 28494 O ILE O 249 -9.395 35.732 56.187 1.00162.95 O +ATOM 28495 CB ILE O 249 -8.638 35.446 59.492 1.00184.05 C +ATOM 28496 CG1 ILE O 249 -8.442 36.313 60.743 1.00163.84 C +ATOM 28497 CG2 ILE O 249 -7.313 35.300 58.761 1.00209.90 C +ATOM 28498 CD1 ILE O 249 -7.819 35.581 61.913 1.00148.92 C +ATOM 28499 N LEU O 250 -10.406 34.092 57.359 1.00156.40 N +ATOM 28500 CA LEU O 250 -10.550 33.205 56.204 1.00154.83 C +ATOM 28501 C LEU O 250 -11.337 33.843 55.060 1.00158.40 C +ATOM 28502 O LEU O 250 -11.013 33.627 53.890 1.00178.22 O +ATOM 28503 CB LEU O 250 -11.209 31.886 56.619 1.00151.37 C +ATOM 28504 CG LEU O 250 -10.276 30.874 57.290 1.00145.81 C +ATOM 28505 CD1 LEU O 250 -11.042 29.729 57.930 1.00136.84 C +ATOM 28506 CD2 LEU O 250 -9.283 30.330 56.281 1.00165.83 C +ATOM 28507 N VAL O 251 -12.384 34.596 55.398 1.00155.42 N +ATOM 28508 CA VAL O 251 -13.197 35.265 54.378 1.00166.37 C +ATOM 28509 C VAL O 251 -12.496 36.507 53.833 1.00169.13 C +ATOM 28510 O VAL O 251 -12.755 36.930 52.702 1.00189.81 O +ATOM 28511 CB VAL O 251 -14.601 35.652 54.898 1.00177.22 C +ATOM 28512 CG1 VAL O 251 -15.321 34.427 55.452 1.00172.67 C +ATOM 28513 CG2 VAL O 251 -14.522 36.766 55.934 1.00188.65 C +ATOM 28514 N LYS O 252 -11.602 37.082 54.634 1.00159.81 N +ATOM 28515 CA LYS O 252 -10.791 38.213 54.188 1.00163.99 C +ATOM 28516 C LYS O 252 -9.812 37.782 53.079 1.00164.60 C +ATOM 28517 O LYS O 252 -9.719 38.424 52.025 1.00113.06 O +ATOM 28518 CB LYS O 252 -10.051 38.802 55.388 1.00155.13 C +ATOM 28519 CG LYS O 252 -9.138 39.977 55.077 1.00161.98 C +ATOM 28520 CD LYS O 252 -8.440 40.452 56.350 1.00169.32 C +ATOM 28521 CE LYS O 252 -6.946 40.659 56.139 1.00164.06 C +ATOM 28522 NZ LYS O 252 -6.206 40.863 57.416 1.00140.84 N +ATOM 28523 N TYR O 253 -9.140 36.655 53.296 1.00180.50 N +ATOM 28524 CA TYR O 253 -8.175 36.129 52.322 1.00185.97 C +ATOM 28525 C TYR O 253 -8.879 35.457 51.153 1.00178.06 C +ATOM 28526 O TYR O 253 -8.379 35.463 50.027 1.00185.32 O +ATOM 28527 CB TYR O 253 -7.186 35.168 53.001 1.00190.73 C +ATOM 28528 CG TYR O 253 -6.207 35.909 53.901 1.00185.02 C +ATOM 28529 CD1 TYR O 253 -5.063 36.502 53.377 1.00161.73 C +ATOM 28530 CD2 TYR O 253 -6.464 36.079 55.262 1.00188.68 C +ATOM 28531 CE1 TYR O 253 -4.193 37.210 54.193 1.00147.80 C +ATOM 28532 CE2 TYR O 253 -5.581 36.769 56.085 1.00159.72 C +ATOM 28533 CZ TYR O 253 -4.450 37.336 55.541 1.00141.89 C +ATOM 28534 OH TYR O 253 -3.583 38.047 56.340 1.00131.04 O +ATOM 28535 N ARG O 254 -10.036 34.864 51.435 1.00168.35 N +ATOM 28536 CA ARG O 254 -10.915 34.353 50.382 1.00156.60 C +ATOM 28537 C ARG O 254 -11.302 35.486 49.438 1.00156.90 C +ATOM 28538 O ARG O 254 -11.353 35.297 48.219 1.00171.81 O +ATOM 28539 CB ARG O 254 -12.183 33.725 50.983 1.00151.05 C +ATOM 28540 CG ARG O 254 -13.092 33.075 49.949 1.00130.95 C +ATOM 28541 CD ARG O 254 -14.103 32.123 50.566 1.00135.29 C +ATOM 28542 NE ARG O 254 -13.506 30.940 51.186 1.00149.24 N +ATOM 28543 CZ ARG O 254 -13.425 30.711 52.497 1.00159.94 C +ATOM 28544 NH1 ARG O 254 -13.902 31.581 53.374 1.00152.02 N +ATOM 28545 NH2 ARG O 254 -12.864 29.588 52.936 1.00164.04 N +ATOM 28546 N HIS O 255 -11.563 36.660 50.015 1.00168.79 N +ATOM 28547 CA HIS O 255 -11.953 37.843 49.243 1.00186.24 C +ATOM 28548 C HIS O 255 -10.818 38.395 48.391 1.00176.70 C +ATOM 28549 O HIS O 255 -11.049 38.885 47.285 1.00134.75 O +ATOM 28550 CB HIS O 255 -12.501 38.942 50.163 1.00207.53 C +ATOM 28551 CG HIS O 255 -13.988 39.104 50.086 1.00205.21 C +ATOM 28552 ND1 HIS O 255 -14.865 38.210 50.663 1.00193.69 N +ATOM 28553 CD2 HIS O 255 -14.752 40.042 49.476 1.00193.85 C +ATOM 28554 CE1 HIS O 255 -16.106 38.600 50.424 1.00189.13 C +ATOM 28555 NE2 HIS O 255 -16.065 39.709 49.708 1.00184.89 N +ATOM 28556 N MET O 256 -9.589 38.293 48.888 1.00175.66 N +ATOM 28557 CA MET O 256 -8.439 38.766 48.114 1.00185.36 C +ATOM 28558 C MET O 256 -8.182 37.901 46.861 1.00214.80 C +ATOM 28559 O MET O 256 -7.616 38.386 45.874 1.00205.64 O +ATOM 28560 CB MET O 256 -7.193 38.851 49.003 1.00172.42 C +ATOM 28561 CG MET O 256 -7.412 39.660 50.278 1.00160.93 C +ATOM 28562 SD MET O 256 -5.930 40.252 51.093 1.00140.93 S +ATOM 28563 CE MET O 256 -5.357 41.466 49.899 1.00107.65 C +ATOM 28564 N SER O 257 -8.643 36.647 46.891 1.00219.09 N +ATOM 28565 CA SER O 257 -8.562 35.738 45.736 1.00189.36 C +ATOM 28566 C SER O 257 -9.603 36.073 44.670 1.00163.84 C +ATOM 28567 O SER O 257 -9.347 36.855 43.760 1.00120.25 O +ATOM 28568 CB SER O 257 -8.760 34.283 46.185 1.00179.29 C +ATOM 28569 OG SER O 257 -8.029 34.015 47.363 1.00200.26 O +TER 28570 SER O 257 +ATOM 28571 N LEU P 2 10.522 55.021 70.032 1.00128.16 N +ATOM 28572 CA LEU P 2 10.692 55.019 68.548 1.00145.72 C +ATOM 28573 C LEU P 2 12.198 55.062 68.193 1.00163.64 C +ATOM 28574 O LEU P 2 12.727 56.064 67.657 1.00136.21 O +ATOM 28575 CB LEU P 2 9.918 56.179 67.896 1.00153.85 C +ATOM 28576 CG LEU P 2 8.380 56.243 68.046 1.00128.34 C +ATOM 28577 CD1 LEU P 2 7.850 57.491 67.340 1.00 94.38 C +ATOM 28578 CD2 LEU P 2 7.641 54.996 67.548 1.00122.14 C +ATOM 28579 N THR P 3 12.874 53.983 68.589 1.00177.50 N +ATOM 28580 CA THR P 3 14.183 53.590 68.065 1.00183.18 C +ATOM 28581 C THR P 3 14.259 52.053 67.874 1.00207.16 C +ATOM 28582 O THR P 3 15.270 51.504 67.421 1.00172.03 O +ATOM 28583 CB THR P 3 15.322 54.022 69.005 1.00157.66 C +ATOM 28584 OG1 THR P 3 15.259 53.256 70.224 1.00126.07 O +ATOM 28585 CG2 THR P 3 15.266 55.535 69.282 1.00128.33 C +ATOM 28586 N ALA P 4 13.202 51.356 68.272 1.00211.62 N +ATOM 28587 CA ALA P 4 12.927 50.007 67.763 1.00168.95 C +ATOM 28588 C ALA P 4 12.390 50.130 66.307 1.00127.75 C +ATOM 28589 O ALA P 4 12.400 51.217 65.748 1.00 95.81 O +ATOM 28590 CB ALA P 4 11.953 49.298 68.708 1.00154.82 C +ATOM 28591 N PRO P 5 11.922 49.034 65.683 1.00101.25 N +ATOM 28592 CA PRO P 5 11.687 49.242 64.265 1.00 93.35 C +ATOM 28593 C PRO P 5 10.367 49.925 63.966 1.00101.28 C +ATOM 28594 O PRO P 5 9.544 50.115 64.862 1.00151.76 O +ATOM 28595 CB PRO P 5 11.668 47.821 63.718 1.00125.65 C +ATOM 28596 CG PRO P 5 11.220 46.946 64.858 1.00122.29 C +ATOM 28597 CD PRO P 5 11.480 47.695 66.136 1.00113.01 C +ATOM 28598 N PRO P 6 10.172 50.354 62.720 1.00135.99 N +ATOM 28599 CA PRO P 6 8.849 50.814 62.256 1.00167.57 C +ATOM 28600 C PRO P 6 7.924 49.655 61.894 1.00177.53 C +ATOM 28601 O PRO P 6 8.400 48.581 61.535 1.00203.76 O +ATOM 28602 CB PRO P 6 9.165 51.657 61.015 1.00175.14 C +ATOM 28603 CG PRO P 6 10.549 51.299 60.607 1.00179.84 C +ATOM 28604 CD PRO P 6 11.251 50.630 61.759 1.00157.03 C +ATOM 28605 N LYS P 7 6.613 49.866 62.001 1.00172.87 N +ATOM 28606 CA LYS P 7 5.637 48.802 61.723 1.00167.80 C +ATOM 28607 C LYS P 7 5.111 48.893 60.296 1.00168.03 C +ATOM 28608 O LYS P 7 5.356 49.875 59.593 1.00135.98 O +ATOM 28609 CB LYS P 7 4.474 48.823 62.724 1.00142.55 C +ATOM 28610 CG LYS P 7 4.850 48.404 64.125 1.00145.23 C +ATOM 28611 CD LYS P 7 4.969 49.576 65.093 1.00140.92 C +ATOM 28612 CE LYS P 7 5.042 49.070 66.525 1.00161.88 C +ATOM 28613 NZ LYS P 7 5.807 49.992 67.407 1.00189.29 N +ATOM 28614 N GLU P 8 4.408 47.846 59.872 1.00181.39 N +ATOM 28615 CA GLU P 8 4.133 47.613 58.458 1.00180.68 C +ATOM 28616 C GLU P 8 3.225 48.662 57.804 1.00139.65 C +ATOM 28617 O GLU P 8 2.085 48.869 58.201 1.00153.18 O +ATOM 28618 CB GLU P 8 3.624 46.199 58.239 1.00198.76 C +ATOM 28619 CG GLU P 8 4.724 45.311 57.598 1.00245.21 C +ATOM 28620 CD GLU P 8 5.342 44.297 58.559 1.00276.07 C +ATOM 28621 OE1 GLU P 8 5.611 44.704 59.717 1.00304.42 O +ATOM 28622 OE2 GLU P 8 5.633 43.126 58.139 1.00303.39 O +ATOM 28623 N ALA P 9 3.782 49.374 56.832 1.00128.50 N +ATOM 28624 CA ALA P 9 3.037 50.329 56.016 1.00117.73 C +ATOM 28625 C ALA P 9 2.602 49.658 54.717 1.00111.74 C +ATOM 28626 O ALA P 9 3.438 49.326 53.869 1.00151.91 O +ATOM 28627 CB ALA P 9 3.908 51.543 55.717 1.00102.49 C +ATOM 28628 N ALA P 10 1.291 49.502 54.556 1.00 94.22 N +ATOM 28629 CA ALA P 10 0.673 48.715 53.473 1.00 99.10 C +ATOM 28630 C ALA P 10 0.626 47.250 53.873 1.00105.83 C +ATOM 28631 O ALA P 10 1.401 46.802 54.717 1.00119.21 O +ATOM 28632 CB ALA P 10 1.364 48.913 52.114 1.00 80.70 C +ATOM 28633 N ARG P 11 -0.282 46.505 53.251 1.00123.64 N +ATOM 28634 CA ARG P 11 -0.448 45.087 53.573 1.00141.89 C +ATOM 28635 C ARG P 11 0.163 44.205 52.470 1.00145.80 C +ATOM 28636 O ARG P 11 0.380 44.652 51.327 1.00156.57 O +ATOM 28637 CB ARG P 11 -1.896 44.738 53.895 1.00152.43 C +ATOM 28638 CG ARG P 11 -2.303 45.052 55.329 1.00161.08 C +ATOM 28639 CD ARG P 11 -3.769 44.842 55.616 1.00181.69 C +ATOM 28640 NE ARG P 11 -4.001 44.729 57.053 1.00185.84 N +ATOM 28641 CZ ARG P 11 -5.204 44.607 57.600 1.00181.30 C +ATOM 28642 NH1 ARG P 11 -6.282 44.568 56.830 1.00175.79 N +ATOM 28643 NH2 ARG P 11 -5.329 44.514 58.914 1.00170.41 N +ATOM 28644 N PRO P 12 0.564 42.981 52.832 1.00151.87 N +ATOM 28645 CA PRO P 12 0.928 42.042 51.783 1.00148.30 C +ATOM 28646 C PRO P 12 -0.311 41.699 50.981 1.00142.08 C +ATOM 28647 O PRO P 12 -1.289 41.191 51.538 1.00157.71 O +ATOM 28648 CB PRO P 12 1.430 40.815 52.550 1.00178.19 C +ATOM 28649 CG PRO P 12 1.674 41.271 53.950 1.00187.75 C +ATOM 28650 CD PRO P 12 0.716 42.403 54.176 1.00173.91 C +ATOM 28651 N THR P 13 -0.321 42.103 49.718 1.00133.51 N +ATOM 28652 CA THR P 13 -1.355 41.671 48.794 1.00126.01 C +ATOM 28653 C THR P 13 -0.865 40.441 48.051 1.00132.79 C +ATOM 28654 O THR P 13 0.349 40.209 47.989 1.00197.18 O +ATOM 28655 CB THR P 13 -1.674 42.784 47.788 1.00113.85 C +ATOM 28656 OG1 THR P 13 -2.823 42.401 47.019 1.00132.09 O +ATOM 28657 CG2 THR P 13 -0.462 43.090 46.864 1.00 95.48 C +ATOM 28658 N LEU P 14 -1.767 39.660 47.464 1.00100.79 N +ATOM 28659 CA LEU P 14 -1.289 38.656 46.515 1.00 96.63 C +ATOM 28660 C LEU P 14 -0.898 39.356 45.176 1.00 70.28 C +ATOM 28661 O LEU P 14 -1.189 40.499 44.994 1.00 45.63 O +ATOM 28662 CB LEU P 14 -2.257 37.486 46.329 1.00 87.71 C +ATOM 28663 CG LEU P 14 -3.671 37.803 45.915 1.00100.01 C +ATOM 28664 CD1 LEU P 14 -4.219 36.706 45.018 1.00 89.53 C +ATOM 28665 CD2 LEU P 14 -4.502 37.930 47.159 1.00115.47 C +ATOM 28666 N MET P 15 -0.028 38.744 44.385 1.00 83.89 N +ATOM 28667 CA MET P 15 0.888 39.511 43.524 1.00 91.20 C +ATOM 28668 C MET P 15 0.065 40.130 42.416 1.00 78.61 C +ATOM 28669 O MET P 15 -0.598 39.414 41.664 1.00 76.38 O +ATOM 28670 CB MET P 15 2.048 38.625 42.960 1.00125.94 C +ATOM 28671 CG MET P 15 3.325 39.404 42.604 1.00117.08 C +ATOM 28672 SD MET P 15 4.382 38.878 41.204 1.00105.19 S +ATOM 28673 CE MET P 15 3.307 37.931 40.128 1.00 89.37 C +ATOM 28674 N PRO P 16 0.171 41.451 42.262 1.00 94.11 N +ATOM 28675 CA PRO P 16 -0.623 42.239 41.326 1.00116.47 C +ATOM 28676 C PRO P 16 -0.426 41.902 39.841 1.00116.18 C +ATOM 28677 O PRO P 16 0.258 42.617 39.107 1.00 89.09 O +ATOM 28678 CB PRO P 16 -0.184 43.678 41.621 1.00127.34 C +ATOM 28679 CG PRO P 16 1.181 43.543 42.177 1.00123.12 C +ATOM 28680 CD PRO P 16 1.150 42.280 42.980 1.00101.40 C +ATOM 28681 N ARG P 17 -1.106 40.854 39.398 1.00121.54 N +ATOM 28682 CA ARG P 17 -1.165 40.518 37.982 1.00124.33 C +ATOM 28683 C ARG P 17 -2.339 41.255 37.333 1.00 94.38 C +ATOM 28684 O ARG P 17 -3.354 41.456 37.966 1.00118.72 O +ATOM 28685 CB ARG P 17 -1.316 38.998 37.821 1.00119.53 C +ATOM 28686 CG ARG P 17 0.015 38.250 37.822 1.00108.91 C +ATOM 28687 CD ARG P 17 -0.132 36.763 38.078 1.00116.91 C +ATOM 28688 NE ARG P 17 -0.331 36.468 39.487 1.00136.85 N +ATOM 28689 CZ ARG P 17 -0.666 35.269 39.956 1.00158.73 C +ATOM 28690 NH1 ARG P 17 -0.752 34.237 39.127 1.00142.54 N +ATOM 28691 NH2 ARG P 17 -0.851 35.095 41.264 1.00153.24 N +ATOM 28692 N ALA P 18 -2.200 41.650 36.078 1.00 82.84 N +ATOM 28693 CA ALA P 18 -3.247 42.422 35.403 1.00 97.37 C +ATOM 28694 C ALA P 18 -3.924 41.668 34.249 1.00100.82 C +ATOM 28695 O ALA P 18 -4.550 40.635 34.470 1.00 65.40 O +ATOM 28696 CB ALA P 18 -2.695 43.762 34.920 1.00126.64 C +ATOM 28697 N GLN P 19 -3.801 42.186 33.021 1.00118.27 N +ATOM 28698 CA GLN P 19 -4.721 41.806 31.944 1.00139.89 C +ATOM 28699 C GLN P 19 -4.484 40.370 31.476 1.00130.07 C +ATOM 28700 O GLN P 19 -5.424 39.572 31.338 1.00 78.69 O +ATOM 28701 CB GLN P 19 -4.587 42.780 30.761 1.00152.81 C +ATOM 28702 CG GLN P 19 -5.607 42.567 29.649 1.00154.33 C +ATOM 28703 CD GLN P 19 -7.041 42.587 30.153 1.00189.17 C +ATOM 28704 OE1 GLN P 19 -7.536 43.622 30.606 1.00235.06 O +ATOM 28705 NE2 GLN P 19 -7.710 41.437 30.102 1.00203.86 N +ATOM 28706 N SER P 20 -3.213 40.083 31.190 1.00133.08 N +ATOM 28707 CA SER P 20 -2.754 38.749 30.817 1.00115.06 C +ATOM 28708 C SER P 20 -3.369 37.695 31.735 1.00107.43 C +ATOM 28709 O SER P 20 -3.959 36.722 31.261 1.00113.00 O +ATOM 28710 CB SER P 20 -1.223 38.701 30.900 1.00102.79 C +ATOM 28711 OG SER P 20 -0.649 39.770 30.161 1.00133.46 O +ATOM 28712 N TYR P 21 -3.264 37.927 33.044 1.00 91.53 N +ATOM 28713 CA TYR P 21 -3.880 37.062 34.059 1.00 92.06 C +ATOM 28714 C TYR P 21 -5.397 36.867 33.881 1.00107.10 C +ATOM 28715 O TYR P 21 -5.895 35.731 33.865 1.00100.14 O +ATOM 28716 CB TYR P 21 -3.630 37.629 35.456 1.00 94.24 C +ATOM 28717 CG TYR P 21 -4.156 36.768 36.579 1.00 99.65 C +ATOM 28718 CD1 TYR P 21 -3.470 35.615 36.964 1.00155.61 C +ATOM 28719 CD2 TYR P 21 -5.328 37.088 37.249 1.00 82.18 C +ATOM 28720 CE1 TYR P 21 -3.945 34.803 37.974 1.00155.85 C +ATOM 28721 CE2 TYR P 21 -5.793 36.300 38.284 1.00 88.36 C +ATOM 28722 CZ TYR P 21 -5.105 35.142 38.629 1.00130.97 C +ATOM 28723 OH TYR P 21 -5.578 34.262 39.581 1.00113.86 O +ATOM 28724 N LYS P 22 -6.121 37.971 33.716 1.00131.68 N +ATOM 28725 CA LYS P 22 -7.572 37.930 33.560 1.00130.47 C +ATOM 28726 C LYS P 22 -8.009 37.124 32.335 1.00113.75 C +ATOM 28727 O LYS P 22 -8.979 36.362 32.394 1.00 71.63 O +ATOM 28728 CB LYS P 22 -8.133 39.354 33.447 1.00149.49 C +ATOM 28729 CG LYS P 22 -8.452 40.012 34.781 1.00146.50 C +ATOM 28730 CD LYS P 22 -9.910 40.016 35.178 1.00134.88 C +ATOM 28731 CE LYS P 22 -9.974 39.999 36.696 1.00115.85 C +ATOM 28732 NZ LYS P 22 -9.590 38.663 37.212 1.00132.73 N +ATOM 28733 N ASP P 23 -7.303 37.319 31.227 1.00101.10 N +ATOM 28734 CA ASP P 23 -7.505 36.496 30.048 1.00113.44 C +ATOM 28735 C ASP P 23 -7.214 35.019 30.337 1.00106.49 C +ATOM 28736 O ASP P 23 -7.959 34.127 29.914 1.00 96.37 O +ATOM 28737 CB ASP P 23 -6.605 36.988 28.900 1.00132.25 C +ATOM 28738 CG ASP P 23 -6.998 38.352 28.417 1.00147.12 C +ATOM 28739 OD1 ASP P 23 -8.218 38.590 28.297 1.00167.75 O +ATOM 28740 OD2 ASP P 23 -6.097 39.168 28.133 1.00159.73 O +ATOM 28741 N LEU P 24 -6.080 34.771 30.989 1.00 93.80 N +ATOM 28742 CA LEU P 24 -5.560 33.418 31.198 1.00 98.43 C +ATOM 28743 C LEU P 24 -6.487 32.587 32.090 1.00101.42 C +ATOM 28744 O LEU P 24 -6.639 31.371 31.880 1.00102.53 O +ATOM 28745 CB LEU P 24 -4.165 33.493 31.827 1.00117.13 C +ATOM 28746 CG LEU P 24 -3.438 32.179 32.151 1.00123.23 C +ATOM 28747 CD1 LEU P 24 -2.671 31.672 30.936 1.00122.11 C +ATOM 28748 CD2 LEU P 24 -2.502 32.370 33.345 1.00110.36 C +ATOM 28749 N THR P 25 -7.122 33.252 33.060 1.00116.81 N +ATOM 28750 CA THR P 25 -8.017 32.576 34.018 1.00139.78 C +ATOM 28751 C THR P 25 -9.375 32.231 33.405 1.00168.70 C +ATOM 28752 O THR P 25 -9.839 31.094 33.511 1.00163.82 O +ATOM 28753 CB THR P 25 -8.251 33.433 35.272 1.00125.18 C +ATOM 28754 OG1 THR P 25 -8.528 34.788 34.888 1.00126.89 O +ATOM 28755 CG2 THR P 25 -7.021 33.412 36.141 1.00149.22 C +ATOM 28756 N HIS P 26 -9.960 33.196 32.697 1.00174.59 N +ATOM 28757 CA HIS P 26 -11.273 33.026 32.074 1.00141.35 C +ATOM 28758 C HIS P 26 -11.187 32.351 30.698 1.00156.79 C +ATOM 28759 O HIS P 26 -11.923 32.690 29.772 1.00186.94 O +ATOM 28760 CB HIS P 26 -11.973 34.389 31.991 1.00161.85 C +ATOM 28761 CG HIS P 26 -12.259 34.993 33.340 1.00176.89 C +ATOM 28762 ND1 HIS P 26 -11.266 35.475 34.169 1.00184.57 N +ATOM 28763 CD2 HIS P 26 -13.422 35.157 34.020 1.00165.70 C +ATOM 28764 CE1 HIS P 26 -11.806 35.928 35.286 1.00151.49 C +ATOM 28765 NE2 HIS P 26 -13.112 35.747 35.223 1.00145.68 N +ATOM 28766 N LEU P 27 -10.269 31.403 30.552 1.00169.27 N +ATOM 28767 CA LEU P 27 -10.168 30.630 29.315 1.00153.72 C +ATOM 28768 C LEU P 27 -11.079 29.408 29.409 1.00151.57 C +ATOM 28769 O LEU P 27 -11.103 28.733 30.435 1.00138.81 O +ATOM 28770 CB LEU P 27 -8.726 30.182 29.064 1.00133.54 C +ATOM 28771 CG LEU P 27 -7.857 31.169 28.286 1.00135.19 C +ATOM 28772 CD1 LEU P 27 -6.386 30.777 28.368 1.00157.63 C +ATOM 28773 CD2 LEU P 27 -8.294 31.262 26.834 1.00139.13 C +ATOM 28774 N PRO P 28 -11.823 29.114 28.329 1.00127.87 N +ATOM 28775 CA PRO P 28 -12.750 27.976 28.301 1.00131.41 C +ATOM 28776 C PRO P 28 -12.035 26.661 28.513 1.00148.42 C +ATOM 28777 O PRO P 28 -11.026 26.417 27.866 1.00189.93 O +ATOM 28778 CB PRO P 28 -13.322 28.023 26.885 1.00145.74 C +ATOM 28779 CG PRO P 28 -12.308 28.775 26.082 1.00136.67 C +ATOM 28780 CD PRO P 28 -11.733 29.788 27.021 1.00128.06 C +ATOM 28781 N ALA P 29 -12.525 25.838 29.437 1.00159.07 N +ATOM 28782 CA ALA P 29 -11.754 24.687 29.925 1.00161.02 C +ATOM 28783 C ALA P 29 -11.704 23.542 28.895 1.00150.68 C +ATOM 28784 O ALA P 29 -12.617 23.386 28.088 1.00130.86 O +ATOM 28785 CB ALA P 29 -12.309 24.196 31.259 1.00128.86 C +ATOM 28786 N PRO P 30 -10.584 22.796 28.867 1.00157.45 N +ATOM 28787 CA PRO P 30 -10.420 21.639 27.982 1.00135.60 C +ATOM 28788 C PRO P 30 -11.192 20.426 28.497 1.00110.13 C +ATOM 28789 O PRO P 30 -11.740 20.474 29.609 1.00 81.24 O +ATOM 28790 CB PRO P 30 -8.923 21.361 28.062 1.00157.92 C +ATOM 28791 CG PRO P 30 -8.519 21.832 29.423 1.00150.04 C +ATOM 28792 CD PRO P 30 -9.417 22.987 29.755 1.00158.59 C +ATOM 28793 N THR P 31 -11.173 19.330 27.735 1.00 93.41 N +ATOM 28794 CA THR P 31 -11.896 18.099 28.130 1.00118.83 C +ATOM 28795 C THR P 31 -11.290 17.418 29.361 1.00117.49 C +ATOM 28796 O THR P 31 -11.982 16.734 30.109 1.00103.17 O +ATOM 28797 CB THR P 31 -11.994 17.060 26.984 1.00121.93 C +ATOM 28798 OG1 THR P 31 -10.695 16.782 26.448 1.00152.32 O +ATOM 28799 CG2 THR P 31 -12.899 17.566 25.866 1.00129.25 C +ATOM 28800 N GLY P 32 -9.992 17.610 29.557 1.00143.91 N +ATOM 28801 CA GLY P 32 -9.326 17.249 30.810 1.00139.11 C +ATOM 28802 C GLY P 32 -8.057 18.066 30.947 1.00123.39 C +ATOM 28803 O GLY P 32 -7.542 18.569 29.941 1.00144.66 O +ATOM 28804 N LYS P 33 -7.593 18.280 32.175 1.00 86.16 N +ATOM 28805 CA LYS P 33 -6.362 19.038 32.355 1.00102.04 C +ATOM 28806 C LYS P 33 -5.174 18.220 31.832 1.00121.94 C +ATOM 28807 O LYS P 33 -5.225 16.992 31.825 1.00113.36 O +ATOM 28808 CB LYS P 33 -6.148 19.426 33.813 1.00 95.51 C +ATOM 28809 CG LYS P 33 -6.728 20.771 34.193 1.00 97.05 C +ATOM 28810 CD LYS P 33 -6.629 20.988 35.692 1.00 99.73 C +ATOM 28811 CE LYS P 33 -7.700 21.940 36.164 1.00123.30 C +ATOM 28812 NZ LYS P 33 -7.727 22.039 37.644 1.00145.72 N +ATOM 28813 N ILE P 34 -4.131 18.906 31.363 1.00142.18 N +ATOM 28814 CA ILE P 34 -2.980 18.239 30.765 1.00137.49 C +ATOM 28815 C ILE P 34 -1.815 18.314 31.760 1.00151.02 C +ATOM 28816 O ILE P 34 -1.706 19.272 32.541 1.00179.00 O +ATOM 28817 CB ILE P 34 -2.642 18.838 29.367 1.00127.82 C +ATOM 28818 CG1 ILE P 34 -3.767 18.538 28.376 1.00114.71 C +ATOM 28819 CG2 ILE P 34 -1.358 18.258 28.797 1.00142.70 C +ATOM 28820 CD1 ILE P 34 -4.435 19.774 27.838 1.00123.98 C +ATOM 28821 N PHE P 35 -1.064 17.221 31.836 1.00135.93 N +ATOM 28822 CA PHE P 35 0.058 17.098 32.747 1.00114.67 C +ATOM 28823 C PHE P 35 1.283 17.738 32.132 1.00116.45 C +ATOM 28824 O PHE P 35 1.702 17.345 31.051 1.00133.55 O +ATOM 28825 CB PHE P 35 0.348 15.629 32.979 1.00100.34 C +ATOM 28826 CG PHE P 35 -0.481 15.008 34.066 1.00 87.48 C +ATOM 28827 CD1 PHE P 35 -0.634 15.625 35.304 1.00 69.19 C +ATOM 28828 CD2 PHE P 35 -0.988 13.731 33.893 1.00110.14 C +ATOM 28829 CE1 PHE P 35 -1.319 15.005 36.327 1.00 76.74 C +ATOM 28830 CE2 PHE P 35 -1.665 13.095 34.919 1.00112.15 C +ATOM 28831 CZ PHE P 35 -1.839 13.735 36.134 1.00107.80 C +ATOM 28832 N VAL P 36 1.916 18.653 32.857 1.00126.34 N +ATOM 28833 CA VAL P 36 3.060 19.376 32.299 1.00122.99 C +ATOM 28834 C VAL P 36 4.272 19.398 33.253 1.00 91.53 C +ATOM 28835 O VAL P 36 4.107 19.424 34.456 1.00 93.49 O +ATOM 28836 CB VAL P 36 2.648 20.810 31.910 1.00106.83 C +ATOM 28837 CG1 VAL P 36 2.518 21.685 33.158 1.00113.26 C +ATOM 28838 CG2 VAL P 36 3.647 21.393 30.935 1.00 91.06 C +ATOM 28839 N SER P 37 5.462 19.468 32.684 1.00 58.51 N +ATOM 28840 CA SER P 37 6.651 19.583 33.460 1.00 50.91 C +ATOM 28841 C SER P 37 7.414 20.799 33.076 1.00 51.61 C +ATOM 28842 O SER P 37 7.613 21.095 31.881 1.00 82.87 O +ATOM 28843 CB SER P 37 7.523 18.410 33.136 1.00 75.99 C +ATOM 28844 OG SER P 37 7.043 17.217 33.715 1.00120.15 O +ATOM 28845 N VAL P 38 7.877 21.548 34.044 1.00 66.14 N +ATOM 28846 CA VAL P 38 8.830 22.633 33.724 1.00118.39 C +ATOM 28847 C VAL P 38 10.099 22.431 34.531 1.00129.16 C +ATOM 28848 O VAL P 38 10.053 22.447 35.775 1.00171.79 O +ATOM 28849 CB VAL P 38 8.294 24.051 34.065 1.00163.97 C +ATOM 28850 CG1 VAL P 38 9.360 25.105 33.785 1.00170.22 C +ATOM 28851 CG2 VAL P 38 7.023 24.380 33.296 1.00145.35 C +ATOM 28852 N TYR P 39 11.225 22.286 33.832 1.00 94.90 N +ATOM 28853 CA TYR P 39 12.493 22.009 34.489 1.00 83.25 C +ATOM 28854 C TYR P 39 13.163 23.357 34.771 1.00 74.27 C +ATOM 28855 O TYR P 39 13.622 23.610 35.884 1.00 61.21 O +ATOM 28856 CB TYR P 39 13.366 21.027 33.641 1.00 88.29 C +ATOM 28857 CG TYR P 39 13.069 19.526 33.883 1.00 85.60 C +ATOM 28858 CD1 TYR P 39 11.912 18.923 33.348 1.00 98.15 C +ATOM 28859 CD2 TYR P 39 13.924 18.722 34.633 1.00 76.02 C +ATOM 28860 CE1 TYR P 39 11.616 17.569 33.563 1.00 65.77 C +ATOM 28861 CE2 TYR P 39 13.614 17.379 34.889 1.00 70.70 C +ATOM 28862 CZ TYR P 39 12.463 16.802 34.347 1.00 63.48 C +ATOM 28863 OH TYR P 39 12.154 15.496 34.608 1.00 34.43 O +ATOM 28864 N ASN P 40 13.313 24.186 33.742 1.00 81.66 N +ATOM 28865 CA ASN P 40 14.072 25.444 33.892 1.00 88.69 C +ATOM 28866 C ASN P 40 13.957 26.429 32.713 1.00 98.36 C +ATOM 28867 O ASN P 40 14.073 26.041 31.551 1.00109.00 O +ATOM 28868 CB ASN P 40 15.556 25.165 34.105 1.00 88.92 C +ATOM 28869 CG ASN P 40 16.267 26.311 34.752 1.00 90.39 C +ATOM 28870 OD1 ASN P 40 15.917 26.749 35.856 1.00 72.36 O +ATOM 28871 ND2 ASN P 40 17.259 26.844 34.046 1.00126.30 N +ATOM 28872 N ILE P 41 13.647 27.687 33.032 1.00 81.35 N +ATOM 28873 CA ILE P 41 13.664 28.760 32.051 1.00 70.95 C +ATOM 28874 C ILE P 41 14.723 29.770 32.468 1.00 63.40 C +ATOM 28875 O ILE P 41 14.602 30.408 33.515 1.00 44.39 O +ATOM 28876 CB ILE P 41 12.284 29.455 31.913 1.00 85.48 C +ATOM 28877 CG1 ILE P 41 11.319 28.647 31.026 1.00 89.98 C +ATOM 28878 CG2 ILE P 41 12.443 30.808 31.237 1.00 91.99 C +ATOM 28879 CD1 ILE P 41 10.788 27.350 31.625 1.00 71.11 C +ATOM 28880 N GLN P 42 15.757 29.922 31.647 1.00 67.68 N +ATOM 28881 CA GLN P 42 16.957 30.685 32.052 1.00 77.49 C +ATOM 28882 C GLN P 42 16.872 32.144 31.711 1.00 77.31 C +ATOM 28883 O GLN P 42 16.121 32.550 30.800 1.00111.70 O +ATOM 28884 CB GLN P 42 18.206 30.133 31.374 1.00114.13 C +ATOM 28885 CG GLN P 42 18.564 28.719 31.791 1.00139.14 C +ATOM 28886 CD GLN P 42 18.542 27.739 30.621 1.00159.29 C +ATOM 28887 OE1 GLN P 42 19.548 27.586 29.908 1.00153.60 O +ATOM 28888 NE2 GLN P 42 17.382 27.104 30.383 1.00116.30 N +ATOM 28889 N ASP P 43 17.649 32.943 32.432 1.00 70.59 N +ATOM 28890 CA ASP P 43 17.855 34.368 32.094 1.00 86.25 C +ATOM 28891 C ASP P 43 18.887 34.507 30.956 1.00 65.66 C +ATOM 28892 O ASP P 43 19.976 35.043 31.181 1.00 43.51 O +ATOM 28893 CB ASP P 43 18.319 35.148 33.355 1.00 78.39 C +ATOM 28894 CG ASP P 43 18.330 36.677 33.159 1.00 95.93 C +ATOM 28895 OD1 ASP P 43 17.325 37.212 32.623 1.00158.08 O +ATOM 28896 OD2 ASP P 43 19.356 37.337 33.428 1.00 55.85 O +ATOM 28897 N GLU P 44 18.541 33.992 29.778 1.00 51.21 N +ATOM 28898 CA GLU P 44 19.458 33.982 28.669 1.00 59.29 C +ATOM 28899 C GLU P 44 19.790 35.420 28.165 1.00 60.60 C +ATOM 28900 O GLU P 44 20.285 35.589 27.006 1.00 42.62 O +ATOM 28901 CB GLU P 44 18.923 33.074 27.531 1.00 75.85 C +ATOM 28902 CG GLU P 44 19.324 31.597 27.635 1.00 99.14 C +ATOM 28903 CD GLU P 44 18.736 30.691 26.515 1.00128.09 C +ATOM 28904 OE1 GLU P 44 18.787 31.044 25.305 1.00133.19 O +ATOM 28905 OE2 GLU P 44 18.300 29.550 26.834 1.00106.46 O +ATOM 28906 N THR P 45 19.489 36.445 28.983 1.00 48.96 N +ATOM 28907 CA THR P 45 19.409 37.849 28.480 1.00 57.87 C +ATOM 28908 C THR P 45 20.747 38.517 28.399 1.00 51.50 C +ATOM 28909 O THR P 45 21.054 39.189 27.420 1.00 31.82 O +ATOM 28910 CB THR P 45 18.453 38.728 29.310 1.00 66.90 C +ATOM 28911 OG1 THR P 45 18.232 39.974 28.637 1.00 77.93 O +ATOM 28912 CG2 THR P 45 19.004 39.004 30.680 1.00 66.20 C +ATOM 28913 N GLY P 46 21.601 38.194 29.359 1.00 69.33 N +ATOM 28914 CA GLY P 46 23.031 38.591 29.285 1.00 99.31 C +ATOM 28915 C GLY P 46 23.284 39.985 29.869 1.00110.02 C +ATOM 28916 O GLY P 46 24.291 40.651 29.634 1.00 55.41 O +ATOM 28917 N GLN P 47 22.380 40.415 30.715 1.00141.89 N +ATOM 28918 CA GLN P 47 22.327 41.802 30.975 1.00133.18 C +ATOM 28919 C GLN P 47 22.212 42.102 32.455 1.00105.41 C +ATOM 28920 O GLN P 47 21.505 41.419 33.204 1.00 98.65 O +ATOM 28921 CB GLN P 47 21.172 42.379 30.201 1.00135.59 C +ATOM 28922 CG GLN P 47 21.385 42.363 28.691 1.00104.86 C +ATOM 28923 CD GLN P 47 22.719 42.941 28.295 1.00 85.05 C +ATOM 28924 OE1 GLN P 47 22.924 44.146 28.370 1.00 80.12 O +ATOM 28925 NE2 GLN P 47 23.613 42.103 27.868 1.00 81.14 N +ATOM 28926 N PHE P 48 22.945 43.126 32.847 1.00 99.84 N +ATOM 28927 CA PHE P 48 22.984 43.572 34.214 1.00109.79 C +ATOM 28928 C PHE P 48 22.644 45.045 34.271 1.00117.51 C +ATOM 28929 O PHE P 48 22.700 45.768 33.266 1.00115.54 O +ATOM 28930 CB PHE P 48 24.380 43.333 34.825 1.00130.22 C +ATOM 28931 CG PHE P 48 24.715 41.900 34.968 1.00135.80 C +ATOM 28932 CD1 PHE P 48 25.061 41.161 33.857 1.00126.10 C +ATOM 28933 CD2 PHE P 48 24.599 41.275 36.186 1.00139.78 C +ATOM 28934 CE1 PHE P 48 25.271 39.814 33.951 1.00119.85 C +ATOM 28935 CE2 PHE P 48 24.835 39.930 36.293 1.00141.05 C +ATOM 28936 CZ PHE P 48 25.188 39.202 35.179 1.00131.44 C +ATOM 28937 N LYS P 49 22.416 45.510 35.493 1.00122.33 N +ATOM 28938 CA LYS P 49 22.042 46.903 35.722 1.00 92.43 C +ATOM 28939 C LYS P 49 23.285 47.766 35.670 1.00 86.75 C +ATOM 28940 O LYS P 49 24.377 47.332 36.059 1.00109.32 O +ATOM 28941 CB LYS P 49 21.296 47.066 37.055 1.00 82.32 C +ATOM 28942 CG LYS P 49 19.955 46.343 37.062 1.00 78.17 C +ATOM 28943 CD LYS P 49 19.040 46.592 38.250 1.00 69.75 C +ATOM 28944 CE LYS P 49 17.703 45.892 37.936 1.00 77.49 C +ATOM 28945 NZ LYS P 49 16.620 46.059 38.941 1.00 75.24 N +ATOM 28946 N PRO P 50 23.126 48.992 35.170 1.00 92.39 N +ATOM 28947 CA PRO P 50 24.241 49.922 35.067 1.00105.90 C +ATOM 28948 C PRO P 50 24.563 50.582 36.413 1.00127.74 C +ATOM 28949 O PRO P 50 23.741 50.529 37.353 1.00157.35 O +ATOM 28950 CB PRO P 50 23.737 50.952 34.039 1.00 99.88 C +ATOM 28951 CG PRO P 50 22.251 50.925 34.175 1.00 91.41 C +ATOM 28952 CD PRO P 50 21.891 49.518 34.553 1.00 91.79 C +ATOM 28953 N TYR P 51 25.711 51.254 36.480 1.00129.56 N +ATOM 28954 CA TYR P 51 25.992 52.120 37.604 1.00126.44 C +ATOM 28955 C TYR P 51 24.807 53.057 37.879 1.00153.45 C +ATOM 28956 O TYR P 51 24.242 53.630 36.942 1.00179.85 O +ATOM 28957 CB TYR P 51 27.246 52.954 37.363 1.00124.88 C +ATOM 28958 CG TYR P 51 27.755 53.551 38.660 1.00149.24 C +ATOM 28959 CD1 TYR P 51 28.567 52.804 39.506 1.00137.06 C +ATOM 28960 CD2 TYR P 51 27.393 54.838 39.069 1.00183.31 C +ATOM 28961 CE1 TYR P 51 29.042 53.309 40.707 1.00124.44 C +ATOM 28962 CE2 TYR P 51 27.885 55.365 40.274 1.00178.73 C +ATOM 28963 CZ TYR P 51 28.683 54.567 41.096 1.00154.10 C +ATOM 28964 OH TYR P 51 29.187 55.018 42.290 1.00185.44 O +ATOM 28965 N PRO P 52 24.407 53.215 39.162 1.00148.52 N +ATOM 28966 CA PRO P 52 25.043 52.746 40.394 1.00138.69 C +ATOM 28967 C PRO P 52 24.624 51.392 40.950 1.00129.54 C +ATOM 28968 O PRO P 52 24.865 51.139 42.135 1.00130.79 O +ATOM 28969 CB PRO P 52 24.663 53.843 41.387 1.00140.55 C +ATOM 28970 CG PRO P 52 23.292 54.261 40.947 1.00122.78 C +ATOM 28971 CD PRO P 52 23.288 54.143 39.449 1.00126.39 C +ATOM 28972 N ALA P 53 24.001 50.539 40.138 1.00105.71 N +ATOM 28973 CA ALA P 53 23.598 49.217 40.628 1.00 97.54 C +ATOM 28974 C ALA P 53 24.803 48.395 40.904 1.00 86.91 C +ATOM 28975 O ALA P 53 25.940 48.716 40.465 1.00 72.73 O +ATOM 28976 CB ALA P 53 22.741 48.480 39.632 1.00109.33 C +ATOM 28977 N SER P 54 24.600 47.351 41.694 1.00 86.86 N +ATOM 28978 CA SER P 54 25.718 46.449 41.903 1.00143.82 C +ATOM 28979 C SER P 54 26.074 45.882 40.538 1.00124.70 C +ATOM 28980 O SER P 54 25.200 45.592 39.725 1.00106.23 O +ATOM 28981 CB SER P 54 25.389 45.335 42.908 1.00180.86 C +ATOM 28982 OG SER P 54 26.201 44.176 42.724 1.00186.94 O +ATOM 28983 N ASN P 55 27.374 45.687 40.321 1.00118.82 N +ATOM 28984 CA ASN P 55 27.873 45.018 39.137 1.00 99.55 C +ATOM 28985 C ASN P 55 27.145 43.690 38.847 1.00104.14 C +ATOM 28986 O ASN P 55 26.959 43.300 37.682 1.00104.08 O +ATOM 28987 CB ASN P 55 29.352 44.748 39.313 1.00 77.25 C +ATOM 28988 CG ASN P 55 30.036 44.507 38.009 1.00106.73 C +ATOM 28989 OD1 ASN P 55 29.540 44.829 36.925 1.00115.65 O +ATOM 28990 ND2 ASN P 55 31.196 43.939 38.105 1.00144.92 N +ATOM 28991 N PHE P 56 26.661 43.055 39.918 1.00110.87 N +ATOM 28992 CA PHE P 56 26.090 41.717 39.855 1.00 84.75 C +ATOM 28993 C PHE P 56 24.583 41.732 39.783 1.00 94.11 C +ATOM 28994 O PHE P 56 23.961 40.676 39.783 1.00133.68 O +ATOM 28995 CB PHE P 56 26.442 40.924 41.113 1.00100.08 C +ATOM 28996 CG PHE P 56 27.917 40.791 41.371 1.00120.20 C +ATOM 28997 CD1 PHE P 56 28.759 40.139 40.460 1.00137.57 C +ATOM 28998 CD2 PHE P 56 28.465 41.318 42.520 1.00 98.03 C +ATOM 28999 CE1 PHE P 56 30.124 40.059 40.685 1.00118.28 C +ATOM 29000 CE2 PHE P 56 29.823 41.203 42.767 1.00109.70 C +ATOM 29001 CZ PHE P 56 30.658 40.593 41.838 1.00114.15 C +ATOM 29002 N SER P 57 23.961 42.903 39.812 1.00 99.56 N +ATOM 29003 CA SER P 57 22.504 42.954 39.755 1.00 88.59 C +ATOM 29004 C SER P 57 22.077 42.672 38.314 1.00 87.69 C +ATOM 29005 O SER P 57 22.337 43.450 37.396 1.00 91.83 O +ATOM 29006 CB SER P 57 21.974 44.301 40.258 1.00104.15 C +ATOM 29007 OG SER P 57 22.070 44.374 41.666 1.00129.33 O +ATOM 29008 N THR P 58 21.389 41.561 38.124 1.00 90.12 N +ATOM 29009 CA THR P 58 20.870 41.216 36.823 1.00110.75 C +ATOM 29010 C THR P 58 19.759 42.150 36.406 1.00140.85 C +ATOM 29011 O THR P 58 18.989 42.672 37.215 1.00222.63 O +ATOM 29012 CB THR P 58 20.296 39.806 36.836 1.00131.39 C +ATOM 29013 OG1 THR P 58 19.215 39.729 37.775 1.00135.19 O +ATOM 29014 CG2 THR P 58 21.355 38.852 37.267 1.00153.92 C +ATOM 29015 N ALA P 59 19.602 42.319 35.123 1.00138.48 N +ATOM 29016 CA ALA P 59 18.568 43.228 34.697 1.00112.01 C +ATOM 29017 C ALA P 59 17.178 42.605 34.833 1.00 87.04 C +ATOM 29018 O ALA P 59 16.176 43.301 34.842 1.00 57.33 O +ATOM 29019 CB ALA P 59 18.828 43.649 33.283 1.00119.32 C +ATOM 29020 N VAL P 60 17.131 41.279 34.924 1.00 84.08 N +ATOM 29021 CA VAL P 60 15.875 40.548 34.884 1.00 76.19 C +ATOM 29022 C VAL P 60 15.897 39.531 36.017 1.00 99.43 C +ATOM 29023 O VAL P 60 16.927 38.883 36.270 1.00132.12 O +ATOM 29024 CB VAL P 60 15.739 39.806 33.546 1.00 82.09 C +ATOM 29025 CG1 VAL P 60 14.455 38.979 33.473 1.00 70.09 C +ATOM 29026 CG2 VAL P 60 15.816 40.790 32.389 1.00 94.90 C +ATOM 29027 N PRO P 61 14.758 39.349 36.699 1.00 96.32 N +ATOM 29028 CA PRO P 61 14.723 38.345 37.786 1.00 97.56 C +ATOM 29029 C PRO P 61 14.890 36.903 37.312 1.00 85.61 C +ATOM 29030 O PRO P 61 14.486 36.566 36.183 1.00 56.59 O +ATOM 29031 CB PRO P 61 13.336 38.514 38.385 1.00112.92 C +ATOM 29032 CG PRO P 61 12.537 39.156 37.297 1.00140.94 C +ATOM 29033 CD PRO P 61 13.486 40.064 36.567 1.00102.97 C +ATOM 29034 N GLN P 62 15.582 36.100 38.126 1.00 96.37 N +ATOM 29035 CA GLN P 62 16.023 34.749 37.715 1.00105.88 C +ATOM 29036 C GLN P 62 14.929 33.774 38.029 1.00126.42 C +ATOM 29037 O GLN P 62 15.206 32.652 38.421 1.00165.29 O +ATOM 29038 CB GLN P 62 17.328 34.323 38.430 1.00 74.52 C +ATOM 29039 CG GLN P 62 18.468 35.337 38.329 1.00 66.04 C +ATOM 29040 CD GLN P 62 18.867 35.617 36.894 1.00 71.68 C +ATOM 29041 OE1 GLN P 62 19.506 34.812 36.261 1.00 48.75 O +ATOM 29042 NE2 GLN P 62 18.406 36.741 36.358 1.00 93.49 N +ATOM 29043 N SER P 63 13.681 34.222 37.904 1.00115.62 N +ATOM 29044 CA SER P 63 12.568 33.547 38.554 1.00139.01 C +ATOM 29045 C SER P 63 11.529 33.059 37.544 1.00128.04 C +ATOM 29046 O SER P 63 10.425 32.636 37.923 1.00184.71 O +ATOM 29047 CB SER P 63 11.942 34.475 39.616 1.00144.47 C +ATOM 29048 OG SER P 63 11.398 35.666 39.061 1.00131.44 O +ATOM 29049 N ALA P 64 11.892 33.107 36.269 1.00 90.75 N +ATOM 29050 CA ALA P 64 10.931 32.898 35.194 1.00107.26 C +ATOM 29051 C ALA P 64 10.270 31.526 35.280 1.00102.84 C +ATOM 29052 O ALA P 64 9.066 31.364 35.000 1.00 73.67 O +ATOM 29053 CB ALA P 64 11.641 33.077 33.872 1.00116.20 C +ATOM 29054 N THR P 65 11.067 30.538 35.688 1.00 99.50 N +ATOM 29055 CA THR P 65 10.605 29.145 35.812 1.00 81.54 C +ATOM 29056 C THR P 65 9.359 29.003 36.675 1.00 86.74 C +ATOM 29057 O THR P 65 8.364 28.417 36.265 1.00123.87 O +ATOM 29058 CB THR P 65 11.673 28.314 36.468 1.00 76.92 C +ATOM 29059 OG1 THR P 65 12.953 28.741 35.978 1.00 88.38 O +ATOM 29060 CG2 THR P 65 11.434 26.835 36.202 1.00 70.23 C +ATOM 29061 N ALA P 66 9.387 29.643 37.837 1.00114.87 N +ATOM 29062 CA ALA P 66 8.284 29.549 38.778 1.00 94.30 C +ATOM 29063 C ALA P 66 7.072 30.335 38.274 1.00 72.14 C +ATOM 29064 O ALA P 66 5.927 29.914 38.467 1.00 71.65 O +ATOM 29065 CB ALA P 66 8.722 30.038 40.145 1.00 89.01 C +ATOM 29066 N MET P 67 7.340 31.425 37.572 1.00 56.78 N +ATOM 29067 CA MET P 67 6.276 32.193 37.005 1.00 73.16 C +ATOM 29068 C MET P 67 5.532 31.330 35.988 1.00 74.96 C +ATOM 29069 O MET P 67 4.282 31.443 35.840 1.00112.01 O +ATOM 29070 CB MET P 67 6.816 33.495 36.349 1.00 72.92 C +ATOM 29071 CG MET P 67 7.310 34.562 37.321 1.00 73.10 C +ATOM 29072 SD MET P 67 8.215 35.887 36.470 1.00 41.20 S +ATOM 29073 CE MET P 67 8.514 37.027 37.819 1.00 60.12 C +ATOM 29074 N LEU P 68 6.302 30.620 35.167 1.00 61.31 N +ATOM 29075 CA LEU P 68 5.706 29.861 34.085 1.00 75.43 C +ATOM 29076 C LEU P 68 4.875 28.748 34.653 1.00 82.11 C +ATOM 29077 O LEU P 68 3.745 28.523 34.196 1.00164.89 O +ATOM 29078 CB LEU P 68 6.755 29.257 33.172 1.00 81.53 C +ATOM 29079 CG LEU P 68 6.178 28.213 32.196 1.00103.03 C +ATOM 29080 CD1 LEU P 68 5.227 28.860 31.168 1.00101.08 C +ATOM 29081 CD2 LEU P 68 7.278 27.451 31.477 1.00106.48 C +ATOM 29082 N VAL P 69 5.396 28.074 35.660 1.00 77.53 N +ATOM 29083 CA VAL P 69 4.641 27.012 36.321 1.00100.59 C +ATOM 29084 C VAL P 69 3.318 27.569 36.873 1.00105.23 C +ATOM 29085 O VAL P 69 2.255 26.952 36.737 1.00 93.25 O +ATOM 29086 CB VAL P 69 5.439 26.341 37.485 1.00 98.61 C +ATOM 29087 CG1 VAL P 69 4.555 25.358 38.236 1.00 82.43 C +ATOM 29088 CG2 VAL P 69 6.671 25.620 36.961 1.00105.73 C +ATOM 29089 N THR P 70 3.399 28.734 37.506 1.00100.82 N +ATOM 29090 CA THR P 70 2.229 29.362 38.107 1.00110.73 C +ATOM 29091 C THR P 70 1.205 29.702 37.033 1.00102.35 C +ATOM 29092 O THR P 70 0.004 29.474 37.197 1.00100.55 O +ATOM 29093 CB THR P 70 2.632 30.620 38.912 1.00108.11 C +ATOM 29094 OG1 THR P 70 3.618 30.240 39.882 1.00155.59 O +ATOM 29095 CG2 THR P 70 1.420 31.239 39.616 1.00 87.41 C +ATOM 29096 N ALA P 71 1.681 30.286 35.943 1.00 94.67 N +ATOM 29097 CA ALA P 71 0.795 30.646 34.848 1.00102.35 C +ATOM 29098 C ALA P 71 0.112 29.389 34.300 1.00 87.89 C +ATOM 29099 O ALA P 71 -1.073 29.401 33.945 1.00 85.19 O +ATOM 29100 CB ALA P 71 1.575 31.401 33.753 1.00 89.72 C +ATOM 29101 N LEU P 72 0.893 28.329 34.141 1.00 89.29 N +ATOM 29102 CA LEU P 72 0.368 27.077 33.605 1.00 93.74 C +ATOM 29103 C LEU P 72 -0.719 26.541 34.520 1.00101.77 C +ATOM 29104 O LEU P 72 -1.589 25.784 34.070 1.00 87.56 O +ATOM 29105 CB LEU P 72 1.482 26.036 33.442 1.00103.87 C +ATOM 29106 CG LEU P 72 2.504 26.331 32.330 1.00 84.13 C +ATOM 29107 CD1 LEU P 72 3.737 25.478 32.594 1.00112.70 C +ATOM 29108 CD2 LEU P 72 1.956 26.063 30.953 1.00 53.94 C +ATOM 29109 N LYS P 73 -0.657 26.897 35.803 1.00105.44 N +ATOM 29110 CA LYS P 73 -1.647 26.399 36.755 1.00110.52 C +ATOM 29111 C LYS P 73 -2.871 27.263 36.725 1.00 84.93 C +ATOM 29112 O LYS P 73 -3.994 26.745 36.730 1.00 92.83 O +ATOM 29113 CB LYS P 73 -1.087 26.338 38.175 1.00128.52 C +ATOM 29114 CG LYS P 73 -1.966 25.570 39.171 1.00137.12 C +ATOM 29115 CD LYS P 73 -1.338 25.538 40.578 1.00126.15 C +ATOM 29116 CE LYS P 73 -2.379 25.419 41.676 1.00126.92 C +ATOM 29117 NZ LYS P 73 -2.283 24.134 42.417 1.00109.49 N +ATOM 29118 N ASP P 74 -2.657 28.574 36.728 1.00 76.82 N +ATOM 29119 CA ASP P 74 -3.770 29.515 36.786 1.00108.79 C +ATOM 29120 C ASP P 74 -4.720 29.366 35.580 1.00 96.70 C +ATOM 29121 O ASP P 74 -5.926 29.635 35.693 1.00 72.56 O +ATOM 29122 CB ASP P 74 -3.260 30.963 36.869 1.00105.25 C +ATOM 29123 CG ASP P 74 -2.597 31.290 38.206 1.00113.70 C +ATOM 29124 OD1 ASP P 74 -2.936 30.669 39.259 1.00130.21 O +ATOM 29125 OD2 ASP P 74 -1.713 32.171 38.198 1.00 94.70 O +ATOM 29126 N SER P 75 -4.178 28.913 34.456 1.00 84.70 N +ATOM 29127 CA SER P 75 -4.949 28.774 33.217 1.00 72.12 C +ATOM 29128 C SER P 75 -6.057 27.733 33.340 1.00 80.35 C +ATOM 29129 O SER P 75 -7.030 27.778 32.583 1.00113.97 O +ATOM 29130 CB SER P 75 -4.024 28.394 32.048 1.00 65.59 C +ATOM 29131 OG SER P 75 -3.815 26.991 31.991 1.00 49.79 O +ATOM 29132 N ARG P 76 -5.872 26.769 34.243 1.00 86.11 N +ATOM 29133 CA ARG P 76 -6.799 25.646 34.447 1.00 98.41 C +ATOM 29134 C ARG P 76 -6.881 24.783 33.216 1.00108.71 C +ATOM 29135 O ARG P 76 -7.936 24.261 32.860 1.00104.38 O +ATOM 29136 CB ARG P 76 -8.183 26.135 34.840 1.00112.68 C +ATOM 29137 CG ARG P 76 -8.228 26.915 36.147 1.00136.17 C +ATOM 29138 CD ARG P 76 -9.659 27.327 36.468 1.00168.86 C +ATOM 29139 NE ARG P 76 -10.144 28.347 35.528 1.00240.47 N +ATOM 29140 CZ ARG P 76 -10.837 28.106 34.412 1.00253.51 C +ATOM 29141 NH1 ARG P 76 -11.161 26.865 34.057 1.00256.41 N +ATOM 29142 NH2 ARG P 76 -11.206 29.120 33.641 1.00242.15 N +ATOM 29143 N TRP P 77 -5.742 24.662 32.549 1.00125.80 N +ATOM 29144 CA TRP P 77 -5.576 23.717 31.450 1.00137.47 C +ATOM 29145 C TRP P 77 -4.584 22.611 31.845 1.00132.44 C +ATOM 29146 O TRP P 77 -4.686 21.469 31.390 1.00128.64 O +ATOM 29147 CB TRP P 77 -5.081 24.462 30.201 1.00118.22 C +ATOM 29148 CG TRP P 77 -6.162 24.912 29.312 1.00115.89 C +ATOM 29149 CD1 TRP P 77 -6.998 25.958 29.517 1.00138.58 C +ATOM 29150 CD2 TRP P 77 -6.538 24.338 28.062 1.00124.78 C +ATOM 29151 NE1 TRP P 77 -7.865 26.085 28.465 1.00148.94 N +ATOM 29152 CE2 TRP P 77 -7.606 25.096 27.557 1.00132.62 C +ATOM 29153 CE3 TRP P 77 -6.072 23.263 27.313 1.00155.09 C +ATOM 29154 CZ2 TRP P 77 -8.225 24.807 26.338 1.00133.77 C +ATOM 29155 CZ3 TRP P 77 -6.689 22.979 26.098 1.00166.06 C +ATOM 29156 CH2 TRP P 77 -7.752 23.751 25.624 1.00132.38 C +ATOM 29157 N PHE P 78 -3.595 22.981 32.658 1.00121.35 N +ATOM 29158 CA PHE P 78 -2.458 22.122 32.972 1.00 91.24 C +ATOM 29159 C PHE P 78 -2.355 21.870 34.479 1.00 90.74 C +ATOM 29160 O PHE P 78 -2.541 22.787 35.291 1.00120.46 O +ATOM 29161 CB PHE P 78 -1.147 22.785 32.513 1.00 86.03 C +ATOM 29162 CG PHE P 78 -1.110 23.150 31.054 1.00 70.93 C +ATOM 29163 CD1 PHE P 78 -0.926 22.183 30.087 1.00 75.75 C +ATOM 29164 CD2 PHE P 78 -1.152 24.475 30.677 1.00 74.58 C +ATOM 29165 CE1 PHE P 78 -0.903 22.519 28.755 1.00 97.17 C +ATOM 29166 CE2 PHE P 78 -1.125 24.825 29.348 1.00 95.39 C +ATOM 29167 CZ PHE P 78 -0.988 23.848 28.383 1.00107.87 C +ATOM 29168 N ILE P 79 -1.966 20.652 34.828 1.00 83.41 N +ATOM 29169 CA ILE P 79 -1.434 20.327 36.142 1.00100.68 C +ATOM 29170 C ILE P 79 0.087 20.339 36.037 1.00 99.04 C +ATOM 29171 O ILE P 79 0.660 19.665 35.169 1.00106.82 O +ATOM 29172 CB ILE P 79 -1.852 18.915 36.566 1.00131.67 C +ATOM 29173 CG1 ILE P 79 -3.348 18.709 36.350 1.00146.25 C +ATOM 29174 CG2 ILE P 79 -1.491 18.660 38.025 1.00149.22 C +ATOM 29175 CD1 ILE P 79 -3.745 17.254 36.201 1.00154.93 C +ATOM 29176 N PRO P 80 0.745 21.169 36.855 1.00 94.99 N +ATOM 29177 CA PRO P 80 2.174 21.134 36.758 1.00 82.05 C +ATOM 29178 C PRO P 80 2.711 20.091 37.710 1.00 63.76 C +ATOM 29179 O PRO P 80 2.310 20.053 38.862 1.00 56.85 O +ATOM 29180 CB PRO P 80 2.590 22.556 37.157 1.00 76.41 C +ATOM 29181 CG PRO P 80 1.405 23.381 36.867 1.00 75.10 C +ATOM 29182 CD PRO P 80 0.286 22.485 37.313 1.00100.56 C +ATOM 29183 N LEU P 81 3.644 19.290 37.218 1.00 46.31 N +ATOM 29184 CA LEU P 81 4.384 18.424 38.056 1.00 37.69 C +ATOM 29185 C LEU P 81 5.651 19.148 38.482 1.00 35.63 C +ATOM 29186 O LEU P 81 6.301 19.871 37.709 1.00 25.49 O +ATOM 29187 CB LEU P 81 4.657 17.162 37.305 1.00 46.28 C +ATOM 29188 CG LEU P 81 3.367 16.561 36.773 1.00 69.06 C +ATOM 29189 CD1 LEU P 81 3.691 15.359 35.896 1.00 79.02 C +ATOM 29190 CD2 LEU P 81 2.454 16.147 37.908 1.00 72.06 C +ATOM 29191 N GLU P 82 5.996 18.926 39.740 1.00 49.04 N +ATOM 29192 CA GLU P 82 7.191 19.539 40.369 1.00 61.62 C +ATOM 29193 C GLU P 82 8.468 18.828 39.885 1.00 77.26 C +ATOM 29194 O GLU P 82 8.783 17.687 40.329 1.00100.28 O +ATOM 29195 CB GLU P 82 7.109 19.539 41.941 1.00 50.94 C +ATOM 29196 CG GLU P 82 8.301 20.127 42.669 1.00 40.76 C +ATOM 29197 CD GLU P 82 8.481 21.646 42.485 1.00 62.17 C +ATOM 29198 OE1 GLU P 82 8.373 22.214 41.344 1.00 90.83 O +ATOM 29199 OE2 GLU P 82 8.680 22.347 43.502 1.00 88.12 O +ATOM 29200 N ARG P 83 9.219 19.543 39.044 1.00 58.04 N +ATOM 29201 CA ARG P 83 10.553 19.147 38.685 1.00 57.50 C +ATOM 29202 C ARG P 83 11.665 20.166 39.093 1.00 92.28 C +ATOM 29203 O ARG P 83 12.849 19.799 39.147 1.00129.38 O +ATOM 29204 CB ARG P 83 10.577 18.880 37.204 1.00 43.18 C +ATOM 29205 CG ARG P 83 9.552 17.886 36.771 1.00 44.78 C +ATOM 29206 CD ARG P 83 9.845 16.490 37.245 1.00 63.77 C +ATOM 29207 NE ARG P 83 8.902 15.590 36.540 1.00 81.54 N +ATOM 29208 CZ ARG P 83 7.824 14.997 37.079 1.00 72.27 C +ATOM 29209 NH1 ARG P 83 7.530 15.180 38.381 1.00 74.43 N +ATOM 29210 NH2 ARG P 83 7.070 14.200 36.312 1.00 49.19 N +ATOM 29211 N GLN P 84 11.317 21.426 39.379 1.00117.37 N +ATOM 29212 CA GLN P 84 12.353 22.434 39.736 1.00105.93 C +ATOM 29213 C GLN P 84 13.067 22.059 41.019 1.00 70.50 C +ATOM 29214 O GLN P 84 14.279 22.030 41.052 1.00 81.77 O +ATOM 29215 CB GLN P 84 11.793 23.852 39.874 1.00129.18 C +ATOM 29216 CG GLN P 84 12.790 24.968 39.504 1.00127.32 C +ATOM 29217 CD GLN P 84 12.243 26.377 39.718 1.00139.57 C +ATOM 29218 OE1 GLN P 84 11.035 26.602 39.598 1.00194.57 O +ATOM 29219 NE2 GLN P 84 13.109 27.308 40.117 1.00100.23 N +ATOM 29220 N GLY P 85 12.343 21.534 41.968 1.00 59.25 N +ATOM 29221 CA GLY P 85 13.034 20.902 43.078 1.00 93.52 C +ATOM 29222 C GLY P 85 13.027 19.357 43.174 1.00 96.70 C +ATOM 29223 O GLY P 85 12.800 18.805 44.279 1.00 79.85 O +ATOM 29224 N LEU P 86 13.241 18.656 42.058 1.00 59.67 N +ATOM 29225 CA LEU P 86 12.922 17.232 42.009 1.00 64.16 C +ATOM 29226 C LEU P 86 13.741 16.472 43.030 1.00 86.61 C +ATOM 29227 O LEU P 86 13.299 15.447 43.592 1.00126.44 O +ATOM 29228 CB LEU P 86 13.186 16.676 40.616 1.00 87.66 C +ATOM 29229 CG LEU P 86 13.140 15.145 40.343 1.00100.28 C +ATOM 29230 CD1 LEU P 86 11.793 14.519 40.656 1.00 64.98 C +ATOM 29231 CD2 LEU P 86 13.521 14.865 38.884 1.00115.37 C +ATOM 29232 N GLN P 87 14.966 16.939 43.257 1.00106.06 N +ATOM 29233 CA GLN P 87 15.900 16.216 44.132 1.00117.51 C +ATOM 29234 C GLN P 87 15.350 16.084 45.579 1.00119.64 C +ATOM 29235 O GLN P 87 15.396 15.005 46.196 1.00 72.52 O +ATOM 29236 CB GLN P 87 17.271 16.897 44.106 1.00116.80 C +ATOM 29237 CG GLN P 87 18.441 15.928 44.236 1.00127.87 C +ATOM 29238 CD GLN P 87 18.280 14.657 43.396 1.00117.73 C +ATOM 29239 OE1 GLN P 87 18.130 14.720 42.173 1.00102.50 O +ATOM 29240 NE2 GLN P 87 18.338 13.496 44.053 1.00 95.38 N +ATOM 29241 N ASN P 88 14.744 17.164 46.064 1.00119.92 N +ATOM 29242 CA ASN P 88 14.138 17.176 47.387 1.00100.67 C +ATOM 29243 C ASN P 88 12.924 16.274 47.473 1.00 90.90 C +ATOM 29244 O ASN P 88 12.687 15.630 48.517 1.00100.53 O +ATOM 29245 CB ASN P 88 13.693 18.584 47.725 1.00 86.85 C +ATOM 29246 CG ASN P 88 14.811 19.563 47.575 1.00 71.43 C +ATOM 29247 OD1 ASN P 88 15.943 19.274 48.026 1.00110.39 O +ATOM 29248 ND2 ASN P 88 14.508 20.749 47.080 1.00 45.75 N +ATOM 29249 N LEU P 89 12.155 16.246 46.383 1.00 56.89 N +ATOM 29250 CA LEU P 89 10.997 15.407 46.305 1.00 51.08 C +ATOM 29251 C LEU P 89 11.405 13.928 46.454 1.00 69.59 C +ATOM 29252 O LEU P 89 10.821 13.139 47.234 1.00 88.75 O +ATOM 29253 CB LEU P 89 10.338 15.648 44.976 1.00 54.12 C +ATOM 29254 CG LEU P 89 8.832 15.464 44.876 1.00 78.28 C +ATOM 29255 CD1 LEU P 89 8.472 14.331 43.948 1.00 75.10 C +ATOM 29256 CD2 LEU P 89 8.178 15.234 46.235 1.00 93.07 C +ATOM 29257 N LEU P 90 12.500 13.568 45.796 1.00 76.80 N +ATOM 29258 CA LEU P 90 12.978 12.185 45.831 1.00 77.64 C +ATOM 29259 C LEU P 90 13.521 11.846 47.214 1.00 74.93 C +ATOM 29260 O LEU P 90 13.505 10.675 47.647 1.00 73.86 O +ATOM 29261 CB LEU P 90 14.045 11.968 44.757 1.00 77.46 C +ATOM 29262 CG LEU P 90 13.544 12.200 43.338 1.00 76.57 C +ATOM 29263 CD1 LEU P 90 14.732 12.434 42.408 1.00 94.84 C +ATOM 29264 CD2 LEU P 90 12.692 11.011 42.891 1.00 73.58 C +ATOM 29265 N ASN P 91 14.048 12.867 47.878 1.00 65.96 N +ATOM 29266 CA ASN P 91 14.633 12.673 49.174 1.00 83.62 C +ATOM 29267 C ASN P 91 13.544 12.373 50.180 1.00 64.75 C +ATOM 29268 O ASN P 91 13.677 11.460 51.002 1.00 76.38 O +ATOM 29269 CB ASN P 91 15.470 13.895 49.577 1.00 99.32 C +ATOM 29270 CG ASN P 91 16.875 13.491 50.020 1.00103.93 C +ATOM 29271 OD1 ASN P 91 17.537 12.738 49.298 1.00 53.71 O +ATOM 29272 ND2 ASN P 91 17.230 13.786 51.287 1.00113.99 N +ATOM 29273 N GLU P 92 12.517 13.193 50.176 1.00 66.71 N +ATOM 29274 CA GLU P 92 11.400 12.977 51.096 1.00 94.52 C +ATOM 29275 C GLU P 92 10.837 11.575 50.886 1.00 81.35 C +ATOM 29276 O GLU P 92 10.370 10.939 51.840 1.00105.69 O +ATOM 29277 CB GLU P 92 10.293 14.054 50.922 1.00100.41 C +ATOM 29278 CG GLU P 92 10.412 15.259 51.839 1.00 83.83 C +ATOM 29279 CD GLU P 92 10.547 14.879 53.318 1.00 91.50 C +ATOM 29280 OE1 GLU P 92 9.650 14.200 53.885 1.00 96.64 O +ATOM 29281 OE2 GLU P 92 11.562 15.295 53.943 1.00 70.15 O +ATOM 29282 N ARG P 93 10.812 11.133 49.635 1.00 59.54 N +ATOM 29283 CA ARG P 93 10.276 9.827 49.333 1.00 74.03 C +ATOM 29284 C ARG P 93 11.206 8.719 49.853 1.00 97.30 C +ATOM 29285 O ARG P 93 10.750 7.681 50.331 1.00 82.90 O +ATOM 29286 CB ARG P 93 10.016 9.727 47.842 1.00 84.59 C +ATOM 29287 CG ARG P 93 8.849 10.607 47.413 1.00 84.01 C +ATOM 29288 CD ARG P 93 8.756 10.811 45.912 1.00104.13 C +ATOM 29289 NE ARG P 93 7.750 9.956 45.291 1.00131.26 N +ATOM 29290 CZ ARG P 93 7.997 8.780 44.709 1.00133.13 C +ATOM 29291 NH1 ARG P 93 9.228 8.280 44.620 1.00 96.83 N +ATOM 29292 NH2 ARG P 93 6.987 8.127 44.161 1.00167.00 N +ATOM 29293 N LYS P 94 12.513 8.987 49.883 1.00131.35 N +ATOM 29294 CA LYS P 94 13.473 8.064 50.532 1.00113.72 C +ATOM 29295 C LYS P 94 13.217 7.979 52.026 1.00 85.35 C +ATOM 29296 O LYS P 94 13.215 6.872 52.596 1.00 97.47 O +ATOM 29297 CB LYS P 94 14.911 8.531 50.342 1.00118.18 C +ATOM 29298 CG LYS P 94 15.584 8.063 49.065 1.00146.07 C +ATOM 29299 CD LYS P 94 16.926 8.762 48.902 1.00162.29 C +ATOM 29300 CE LYS P 94 17.861 8.035 47.947 1.00172.91 C +ATOM 29301 NZ LYS P 94 18.993 8.920 47.561 1.00166.42 N +ATOM 29302 N ILE P 95 12.944 9.133 52.645 1.00 54.68 N +ATOM 29303 CA ILE P 95 12.708 9.153 54.071 1.00 52.86 C +ATOM 29304 C ILE P 95 11.414 8.425 54.438 1.00 62.91 C +ATOM 29305 O ILE P 95 11.338 7.748 55.505 1.00 57.69 O +ATOM 29306 CB ILE P 95 12.665 10.562 54.660 1.00 50.77 C +ATOM 29307 CG1 ILE P 95 13.827 11.377 54.154 1.00 54.92 C +ATOM 29308 CG2 ILE P 95 12.768 10.466 56.174 1.00 51.04 C +ATOM 29309 CD1 ILE P 95 14.066 12.672 54.911 1.00 67.01 C +ATOM 29310 N ILE P 96 10.378 8.650 53.612 1.00 61.03 N +ATOM 29311 CA ILE P 96 9.096 7.968 53.757 1.00 59.15 C +ATOM 29312 C ILE P 96 9.316 6.489 53.725 1.00 61.24 C +ATOM 29313 O ILE P 96 8.982 5.787 54.678 1.00 59.75 O +ATOM 29314 CB ILE P 96 8.107 8.336 52.653 1.00 68.11 C +ATOM 29315 CG1 ILE P 96 7.664 9.794 52.818 1.00 99.03 C +ATOM 29316 CG2 ILE P 96 6.873 7.467 52.758 1.00 73.11 C +ATOM 29317 CD1 ILE P 96 6.623 10.233 51.807 1.00124.16 C +ATOM 29318 N ARG P 97 9.888 6.011 52.628 1.00 83.75 N +ATOM 29319 CA ARG P 97 10.094 4.565 52.445 1.00100.38 C +ATOM 29320 C ARG P 97 10.946 3.947 53.565 1.00 94.98 C +ATOM 29321 O ARG P 97 10.751 2.786 53.951 1.00 98.30 O +ATOM 29322 CB ARG P 97 10.745 4.272 51.091 1.00118.41 C +ATOM 29323 CG ARG P 97 9.790 3.767 50.020 1.00124.23 C +ATOM 29324 CD ARG P 97 10.529 3.434 48.726 1.00112.82 C +ATOM 29325 NE ARG P 97 10.787 4.624 47.912 1.00 98.17 N +ATOM 29326 CZ ARG P 97 10.062 5.000 46.857 1.00 80.08 C +ATOM 29327 NH1 ARG P 97 9.024 4.286 46.443 1.00 60.78 N +ATOM 29328 NH2 ARG P 97 10.378 6.116 46.219 1.00105.23 N +ATOM 29329 N ALA P 98 11.863 4.738 54.112 1.00 93.21 N +ATOM 29330 CA ALA P 98 12.686 4.280 55.214 1.00 96.13 C +ATOM 29331 C ALA P 98 11.890 4.262 56.527 1.00114.93 C +ATOM 29332 O ALA P 98 12.172 3.450 57.417 1.00109.29 O +ATOM 29333 CB ALA P 98 13.909 5.165 55.342 1.00 87.92 C +ATOM 29334 N ALA P 99 10.893 5.148 56.626 1.00106.79 N +ATOM 29335 CA ALA P 99 10.022 5.233 57.809 1.00 84.89 C +ATOM 29336 C ALA P 99 9.125 4.019 57.958 1.00 96.44 C +ATOM 29337 O ALA P 99 9.055 3.394 59.027 1.00157.65 O +ATOM 29338 CB ALA P 99 9.167 6.468 57.744 1.00 67.78 C +ATOM 29339 N GLN P 100 8.435 3.667 56.881 1.00 86.24 N +ATOM 29340 CA GLN P 100 7.310 2.725 56.975 1.00 98.53 C +ATOM 29341 C GLN P 100 7.598 1.325 56.456 1.00 96.91 C +ATOM 29342 O GLN P 100 6.696 0.492 56.376 1.00121.40 O +ATOM 29343 CB GLN P 100 6.065 3.305 56.282 1.00 94.04 C +ATOM 29344 CG GLN P 100 6.325 3.976 54.950 1.00 91.13 C +ATOM 29345 CD GLN P 100 5.321 5.076 54.627 1.00 86.55 C +ATOM 29346 OE1 GLN P 100 5.184 6.088 55.353 1.00 61.54 O +ATOM 29347 NE2 GLN P 100 4.646 4.908 53.502 1.00100.07 N +ATOM 29348 N GLU P 101 8.851 1.059 56.120 1.00 93.88 N +ATOM 29349 CA GLU P 101 9.209 -0.237 55.558 1.00113.49 C +ATOM 29350 C GLU P 101 9.073 -1.374 56.575 1.00114.46 C +ATOM 29351 O GLU P 101 8.943 -2.546 56.192 1.00100.33 O +ATOM 29352 CB GLU P 101 10.629 -0.201 54.969 1.00133.02 C +ATOM 29353 CG GLU P 101 11.703 0.331 55.912 1.00115.18 C +ATOM 29354 CD GLU P 101 13.093 0.259 55.302 1.00122.51 C +ATOM 29355 OE1 GLU P 101 13.196 0.120 54.063 1.00113.67 O +ATOM 29356 OE2 GLU P 101 14.092 0.340 56.060 1.00188.50 O +ATOM 29357 N ASN P 102 9.156 -1.047 57.862 1.00106.52 N +ATOM 29358 CA ASN P 102 9.138 -2.076 58.898 1.00116.46 C +ATOM 29359 C ASN P 102 7.735 -2.356 59.411 1.00138.06 C +ATOM 29360 O ASN P 102 7.549 -3.220 60.269 1.00149.14 O +ATOM 29361 CB ASN P 102 10.036 -1.676 60.068 1.00114.74 C +ATOM 29362 CG ASN P 102 11.512 -1.784 59.741 1.00125.85 C +ATOM 29363 OD1 ASN P 102 12.085 -2.876 59.708 1.00 81.77 O +ATOM 29364 ND2 ASN P 102 12.113 -0.648 59.416 1.00169.16 N +ATOM 29365 N GLY P 103 6.749 -1.613 58.915 1.00138.83 N +ATOM 29366 CA GLY P 103 5.369 -1.804 59.356 1.00117.85 C +ATOM 29367 C GLY P 103 5.169 -1.583 60.846 1.00 97.54 C +ATOM 29368 O GLY P 103 4.343 -2.239 61.484 1.00 92.82 O +ATOM 29369 N THR P 104 5.923 -0.650 61.406 1.00 94.13 N +ATOM 29370 CA THR P 104 5.644 -0.178 62.741 1.00107.81 C +ATOM 29371 C THR P 104 4.897 1.149 62.666 1.00122.72 C +ATOM 29372 O THR P 104 4.115 1.453 63.559 1.00143.42 O +ATOM 29373 CB THR P 104 6.921 -0.022 63.593 1.00117.60 C +ATOM 29374 OG1 THR P 104 7.770 0.999 63.043 1.00107.85 O +ATOM 29375 CG2 THR P 104 7.669 -1.346 63.666 1.00112.00 C +ATOM 29376 N VAL P 105 5.069 1.905 61.582 1.00131.46 N +ATOM 29377 CA VAL P 105 4.523 3.272 61.528 1.00143.61 C +ATOM 29378 C VAL P 105 3.006 3.256 61.662 1.00139.29 C +ATOM 29379 O VAL P 105 2.325 2.388 61.102 1.00113.95 O +ATOM 29380 CB VAL P 105 4.975 4.077 60.268 1.00146.84 C +ATOM 29381 CG1 VAL P 105 3.902 5.056 59.788 1.00 98.50 C +ATOM 29382 CG2 VAL P 105 6.280 4.846 60.556 1.00179.15 C +ATOM 29383 N ALA P 106 2.506 4.223 62.435 1.00156.11 N +ATOM 29384 CA ALA P 106 1.103 4.300 62.819 1.00150.92 C +ATOM 29385 C ALA P 106 0.201 4.460 61.598 1.00164.29 C +ATOM 29386 O ALA P 106 0.479 5.271 60.709 1.00213.26 O +ATOM 29387 CB ALA P 106 0.894 5.457 63.784 1.00145.47 C +ATOM 29388 N ILE P 107 -0.876 3.677 61.561 1.00145.74 N +ATOM 29389 CA ILE P 107 -1.756 3.600 60.390 1.00135.01 C +ATOM 29390 C ILE P 107 -2.371 4.967 60.008 1.00128.12 C +ATOM 29391 O ILE P 107 -2.623 5.248 58.834 1.00 93.43 O +ATOM 29392 CB ILE P 107 -2.873 2.548 60.619 1.00119.46 C +ATOM 29393 CG1 ILE P 107 -3.615 2.235 59.311 1.00112.49 C +ATOM 29394 CG2 ILE P 107 -3.849 3.022 61.693 1.00105.97 C +ATOM 29395 CD1 ILE P 107 -2.734 1.739 58.183 1.00112.99 C +ATOM 29396 N ASN P 108 -2.580 5.819 61.005 1.00142.61 N +ATOM 29397 CA ASN P 108 -3.050 7.191 60.776 1.00161.67 C +ATOM 29398 C ASN P 108 -1.968 8.044 60.119 1.00158.38 C +ATOM 29399 O ASN P 108 -2.252 8.935 59.324 1.00158.62 O +ATOM 29400 CB ASN P 108 -3.457 7.847 62.103 1.00181.72 C +ATOM 29401 CG ASN P 108 -3.978 6.846 63.118 1.00195.88 C +ATOM 29402 OD1 ASN P 108 -5.164 6.518 63.126 1.00240.89 O +ATOM 29403 ND2 ASN P 108 -3.091 6.352 63.980 1.00185.14 N +ATOM 29404 N ASN P 109 -0.725 7.785 60.505 1.00147.74 N +ATOM 29405 CA ASN P 109 0.409 8.588 60.078 1.00139.46 C +ATOM 29406 C ASN P 109 0.991 8.137 58.739 1.00138.31 C +ATOM 29407 O ASN P 109 1.749 8.875 58.107 1.00147.24 O +ATOM 29408 CB ASN P 109 1.493 8.547 61.155 1.00139.18 C +ATOM 29409 CG ASN P 109 1.753 9.912 61.757 1.00140.39 C +ATOM 29410 OD1 ASN P 109 2.839 10.473 61.603 1.00167.65 O +ATOM 29411 ND2 ASN P 109 0.752 10.465 62.426 1.00127.59 N +ATOM 29412 N ARG P 110 0.638 6.918 58.329 1.00123.28 N +ATOM 29413 CA ARG P 110 1.210 6.258 57.143 1.00 96.55 C +ATOM 29414 C ARG P 110 1.031 7.101 55.887 1.00 97.82 C +ATOM 29415 O ARG P 110 -0.047 7.660 55.657 1.00134.05 O +ATOM 29416 CB ARG P 110 0.516 4.908 56.932 1.00 90.49 C +ATOM 29417 CG ARG P 110 1.308 3.903 56.132 1.00103.98 C +ATOM 29418 CD ARG P 110 1.064 2.482 56.610 1.00119.18 C +ATOM 29419 NE ARG P 110 -0.064 1.868 55.903 1.00124.15 N +ATOM 29420 CZ ARG P 110 0.006 0.760 55.155 1.00127.79 C +ATOM 29421 NH1 ARG P 110 1.153 0.088 54.999 1.00101.04 N +ATOM 29422 NH2 ARG P 110 -1.099 0.294 54.576 1.00141.95 N +ATOM 29423 N ILE P 111 2.087 7.234 55.088 1.00 91.88 N +ATOM 29424 CA ILE P 111 1.979 7.942 53.809 1.00 93.31 C +ATOM 29425 C ILE P 111 2.057 6.960 52.665 1.00 96.48 C +ATOM 29426 O ILE P 111 3.092 6.341 52.485 1.00100.31 O +ATOM 29427 CB ILE P 111 3.081 8.992 53.623 1.00 83.25 C +ATOM 29428 CG1 ILE P 111 2.931 10.086 54.683 1.00108.43 C +ATOM 29429 CG2 ILE P 111 2.991 9.609 52.234 1.00 77.72 C +ATOM 29430 CD1 ILE P 111 4.119 11.025 54.799 1.00110.97 C +ATOM 29431 N PRO P 112 0.974 6.835 51.876 1.00107.81 N +ATOM 29432 CA PRO P 112 0.968 5.885 50.782 1.00104.49 C +ATOM 29433 C PRO P 112 1.714 6.451 49.577 1.00115.78 C +ATOM 29434 O PRO P 112 1.453 7.587 49.150 1.00 97.74 O +ATOM 29435 CB PRO P 112 -0.520 5.718 50.479 1.00102.83 C +ATOM 29436 CG PRO P 112 -1.107 7.049 50.807 1.00112.73 C +ATOM 29437 CD PRO P 112 -0.241 7.673 51.875 1.00116.44 C +ATOM 29438 N LEU P 113 2.650 5.665 49.051 1.00130.53 N +ATOM 29439 CA LEU P 113 3.531 6.127 47.987 1.00108.62 C +ATOM 29440 C LEU P 113 3.173 5.525 46.651 1.00 96.09 C +ATOM 29441 O LEU P 113 2.835 4.338 46.524 1.00 81.84 O +ATOM 29442 CB LEU P 113 4.985 5.831 48.315 1.00101.63 C +ATOM 29443 CG LEU P 113 5.686 6.890 49.158 1.00107.05 C +ATOM 29444 CD1 LEU P 113 7.139 6.484 49.315 1.00103.58 C +ATOM 29445 CD2 LEU P 113 5.582 8.279 48.532 1.00116.13 C +ATOM 29446 N GLN P 114 3.273 6.375 45.645 1.00 81.62 N +ATOM 29447 CA GLN P 114 2.757 6.080 44.329 1.00 84.65 C +ATOM 29448 C GLN P 114 3.805 6.597 43.393 1.00 79.04 C +ATOM 29449 O GLN P 114 4.509 7.552 43.742 1.00129.03 O +ATOM 29450 CB GLN P 114 1.453 6.828 44.102 1.00 81.85 C +ATOM 29451 CG GLN P 114 0.513 6.188 43.104 1.00 76.59 C +ATOM 29452 CD GLN P 114 -0.267 7.240 42.358 1.00 67.42 C +ATOM 29453 OE1 GLN P 114 -0.455 7.125 41.155 1.00 57.20 O +ATOM 29454 NE2 GLN P 114 -0.656 8.310 43.059 1.00 67.65 N +ATOM 29455 N SER P 115 3.990 5.916 42.269 1.00 59.00 N +ATOM 29456 CA SER P 115 5.055 6.267 41.349 1.00 69.58 C +ATOM 29457 C SER P 115 4.898 7.721 40.917 1.00 83.97 C +ATOM 29458 O SER P 115 3.774 8.275 40.993 1.00126.25 O +ATOM 29459 CB SER P 115 5.023 5.347 40.141 1.00 67.51 C +ATOM 29460 OG SER P 115 3.731 5.268 39.583 1.00 64.37 O +ATOM 29461 N LEU P 116 5.996 8.381 40.528 1.00 67.11 N +ATOM 29462 CA LEU P 116 5.891 9.823 40.354 1.00 79.44 C +ATOM 29463 C LEU P 116 5.046 10.051 39.121 1.00 92.29 C +ATOM 29464 O LEU P 116 5.359 9.490 38.069 1.00132.52 O +ATOM 29465 CB LEU P 116 7.241 10.486 40.207 1.00 76.35 C +ATOM 29466 CG LEU P 116 8.129 10.430 41.431 1.00 99.64 C +ATOM 29467 CD1 LEU P 116 9.086 9.229 41.386 1.00128.96 C +ATOM 29468 CD2 LEU P 116 8.902 11.742 41.503 1.00113.68 C +ATOM 29469 N THR P 117 3.966 10.824 39.259 1.00 89.26 N +ATOM 29470 CA THR P 117 3.127 11.180 38.128 1.00113.91 C +ATOM 29471 C THR P 117 3.968 11.830 37.029 1.00122.04 C +ATOM 29472 O THR P 117 4.815 12.674 37.321 1.00121.36 O +ATOM 29473 CB THR P 117 2.048 12.194 38.520 1.00139.83 C +ATOM 29474 OG1 THR P 117 1.303 11.688 39.637 1.00192.28 O +ATOM 29475 CG2 THR P 117 1.098 12.417 37.362 1.00129.67 C +ATOM 29476 N ALA P 118 3.764 11.390 35.784 1.00111.90 N +ATOM 29477 CA ALA P 118 4.707 11.675 34.692 1.00 85.83 C +ATOM 29478 C ALA P 118 4.038 12.428 33.631 1.00 79.55 C +ATOM 29479 O ALA P 118 2.889 12.132 33.266 1.00 61.80 O +ATOM 29480 CB ALA P 118 5.278 10.400 34.098 1.00103.32 C +ATOM 29481 N ALA P 119 4.781 13.386 33.103 1.00101.13 N +ATOM 29482 CA ALA P 119 4.240 14.362 32.160 1.00107.53 C +ATOM 29483 C ALA P 119 4.329 13.857 30.721 1.00 97.80 C +ATOM 29484 O ALA P 119 5.162 13.001 30.413 1.00 60.87 O +ATOM 29485 CB ALA P 119 4.999 15.659 32.276 1.00110.05 C +ATOM 29486 N ASN P 120 3.438 14.353 29.857 1.00 87.00 N +ATOM 29487 CA ASN P 120 3.486 13.984 28.437 1.00 88.96 C +ATOM 29488 C ASN P 120 4.163 15.028 27.592 1.00 83.37 C +ATOM 29489 O ASN P 120 4.995 14.729 26.749 1.00 87.54 O +ATOM 29490 CB ASN P 120 2.093 13.747 27.860 1.00106.19 C +ATOM 29491 CG ASN P 120 2.137 13.385 26.384 1.00125.44 C +ATOM 29492 OD1 ASN P 120 3.045 12.670 25.918 1.00130.00 O +ATOM 29493 ND2 ASN P 120 1.161 13.898 25.630 1.00135.13 N +ATOM 29494 N ILE P 121 3.776 16.272 27.793 1.00 76.42 N +ATOM 29495 CA ILE P 121 4.499 17.351 27.181 1.00 86.52 C +ATOM 29496 C ILE P 121 5.274 18.061 28.275 1.00 85.20 C +ATOM 29497 O ILE P 121 4.799 18.252 29.384 1.00 97.99 O +ATOM 29498 CB ILE P 121 3.557 18.314 26.413 1.00113.42 C +ATOM 29499 CG1 ILE P 121 2.730 19.209 27.360 1.00136.99 C +ATOM 29500 CG2 ILE P 121 2.646 17.529 25.472 1.00105.49 C +ATOM 29501 CD1 ILE P 121 3.126 20.675 27.331 1.00131.03 C +ATOM 29502 N MET P 122 6.463 18.491 27.950 1.00 88.14 N +ATOM 29503 CA MET P 122 7.091 19.442 28.797 1.00104.92 C +ATOM 29504 C MET P 122 7.303 20.741 28.006 1.00 82.57 C +ATOM 29505 O MET P 122 7.681 20.705 26.839 1.00 87.81 O +ATOM 29506 CB MET P 122 8.371 18.817 29.402 1.00144.79 C +ATOM 29507 CG MET P 122 9.420 18.302 28.424 1.00137.20 C +ATOM 29508 SD MET P 122 11.074 18.459 29.177 1.00 99.51 S +ATOM 29509 CE MET P 122 12.052 18.961 27.795 1.00110.61 C +ATOM 29510 N VAL P 123 7.175 21.875 28.689 1.00 48.59 N +ATOM 29511 CA VAL P 123 7.498 23.148 28.084 1.00 45.72 C +ATOM 29512 C VAL P 123 8.670 23.885 28.708 1.00 48.30 C +ATOM 29513 O VAL P 123 8.763 24.019 29.927 1.00 58.98 O +ATOM 29514 CB VAL P 123 6.316 24.057 28.170 1.00 53.01 C +ATOM 29515 CG1 VAL P 123 5.647 23.940 29.529 1.00 50.20 C +ATOM 29516 CG2 VAL P 123 6.710 25.513 27.854 1.00 68.01 C +ATOM 29517 N GLU P 124 9.623 24.310 27.875 1.00 66.78 N +ATOM 29518 CA GLU P 124 10.780 25.072 28.354 1.00 93.44 C +ATOM 29519 C GLU P 124 10.979 26.266 27.473 1.00 90.38 C +ATOM 29520 O GLU P 124 10.332 26.413 26.462 1.00 59.07 O +ATOM 29521 CB GLU P 124 12.092 24.264 28.383 1.00121.87 C +ATOM 29522 CG GLU P 124 12.215 23.164 27.346 1.00135.29 C +ATOM 29523 CD GLU P 124 13.298 22.160 27.704 1.00152.68 C +ATOM 29524 OE1 GLU P 124 13.491 21.877 28.906 1.00131.04 O +ATOM 29525 OE2 GLU P 124 13.985 21.707 26.771 1.00193.67 O +ATOM 29526 N GLY P 125 11.828 27.175 27.935 1.00114.67 N +ATOM 29527 CA GLY P 125 11.990 28.468 27.287 1.00100.84 C +ATOM 29528 C GLY P 125 13.114 29.277 27.892 1.00 67.04 C +ATOM 29529 O GLY P 125 13.969 28.737 28.586 1.00 65.73 O +ATOM 29530 N SER P 126 13.110 30.567 27.623 1.00 54.64 N +ATOM 29531 CA SER P 126 14.233 31.385 28.005 1.00 67.38 C +ATOM 29532 C SER P 126 13.839 32.825 27.977 1.00 93.51 C +ATOM 29533 O SER P 126 12.958 33.224 27.191 1.00123.74 O +ATOM 29534 CB SER P 126 15.406 31.231 27.032 1.00 65.84 C +ATOM 29535 OG SER P 126 15.476 29.934 26.465 1.00 59.42 O +ATOM 29536 N ILE P 127 14.449 33.624 28.854 1.00 78.06 N +ATOM 29537 CA ILE P 127 14.276 35.063 28.755 1.00 90.33 C +ATOM 29538 C ILE P 127 15.264 35.469 27.691 1.00 91.79 C +ATOM 29539 O ILE P 127 16.441 35.557 27.954 1.00 67.65 O +ATOM 29540 CB ILE P 127 14.503 35.829 30.088 1.00 73.85 C +ATOM 29541 CG1 ILE P 127 13.364 35.537 31.090 1.00 53.06 C +ATOM 29542 CG2 ILE P 127 14.557 37.330 29.828 1.00 83.52 C +ATOM 29543 CD1 ILE P 127 13.816 35.598 32.523 1.00 47.84 C +ATOM 29544 N ILE P 128 14.743 35.730 26.489 1.00103.83 N +ATOM 29545 CA ILE P 128 15.543 36.140 25.331 1.00107.16 C +ATOM 29546 C ILE P 128 15.549 37.658 25.267 1.00 83.06 C +ATOM 29547 O ILE P 128 14.511 38.312 25.030 1.00183.42 O +ATOM 29548 CB ILE P 128 14.979 35.524 24.035 1.00147.39 C +ATOM 29549 CG1 ILE P 128 13.490 35.844 23.870 1.00188.42 C +ATOM 29550 CG2 ILE P 128 15.074 34.008 24.092 1.00174.26 C +ATOM 29551 CD1 ILE P 128 13.036 35.813 22.421 1.00223.61 C +ATOM 29552 N GLY P 129 16.609 38.224 25.804 1.00 75.26 N +ATOM 29553 CA GLY P 129 16.790 39.659 25.714 1.00118.59 C +ATOM 29554 C GLY P 129 16.107 40.612 26.718 1.00145.17 C +ATOM 29555 O GLY P 129 14.918 40.499 27.062 1.00115.69 O +ATOM 29556 N TYR P 130 16.894 41.588 27.157 1.00145.39 N +ATOM 29557 CA TYR P 130 16.379 42.789 27.793 1.00116.34 C +ATOM 29558 C TYR P 130 17.227 43.921 27.257 1.00108.59 C +ATOM 29559 O TYR P 130 18.424 43.995 27.545 1.00143.30 O +ATOM 29560 CB TYR P 130 16.517 42.676 29.315 1.00106.59 C +ATOM 29561 CG TYR P 130 16.163 43.912 30.110 1.00113.07 C +ATOM 29562 CD1 TYR P 130 16.968 45.060 30.061 1.00111.97 C +ATOM 29563 CD2 TYR P 130 15.071 43.909 30.980 1.00118.02 C +ATOM 29564 CE1 TYR P 130 16.653 46.188 30.810 1.00122.19 C +ATOM 29565 CE2 TYR P 130 14.756 45.025 31.749 1.00139.11 C +ATOM 29566 CZ TYR P 130 15.553 46.159 31.668 1.00137.00 C +ATOM 29567 OH TYR P 130 15.161 47.277 32.362 1.00101.67 O +ATOM 29568 N GLU P 131 16.659 44.718 26.375 1.00 84.18 N +ATOM 29569 CA GLU P 131 17.342 45.912 25.942 1.00108.38 C +ATOM 29570 C GLU P 131 16.834 47.076 26.786 1.00120.18 C +ATOM 29571 O GLU P 131 15.681 47.087 27.206 1.00 76.99 O +ATOM 29572 CB GLU P 131 17.096 46.132 24.459 1.00139.86 C +ATOM 29573 CG GLU P 131 17.923 47.232 23.814 1.00148.32 C +ATOM 29574 CD GLU P 131 19.289 46.770 23.324 1.00163.31 C +ATOM 29575 OE1 GLU P 131 19.440 45.576 22.971 1.00181.95 O +ATOM 29576 OE2 GLU P 131 20.209 47.620 23.249 1.00202.22 O +ATOM 29577 N SER P 132 17.713 48.042 27.063 1.00138.50 N +ATOM 29578 CA SER P 132 17.393 49.116 28.003 1.00130.99 C +ATOM 29579 C SER P 132 17.414 50.507 27.336 1.00150.19 C +ATOM 29580 O SER P 132 18.283 50.796 26.504 1.00110.39 O +ATOM 29581 CB SER P 132 18.350 49.080 29.186 1.00120.51 C +ATOM 29582 OG SER P 132 19.195 50.220 29.191 1.00164.84 O +ATOM 29583 N ASN P 133 16.462 51.361 27.727 1.00154.48 N +ATOM 29584 CA ASN P 133 16.217 52.651 27.061 1.00126.85 C +ATOM 29585 C ASN P 133 16.109 52.494 25.562 1.00145.51 C +ATOM 29586 O ASN P 133 16.891 53.086 24.799 1.00143.72 O +ATOM 29587 CB ASN P 133 17.305 53.672 27.394 1.00101.76 C +ATOM 29588 CG ASN P 133 17.370 53.988 28.870 1.00114.27 C +ATOM 29589 OD1 ASN P 133 16.375 53.875 29.609 1.00 83.64 O +ATOM 29590 ND2 ASN P 133 18.565 54.333 29.330 1.00152.30 N +ATOM 29591 N VAL P 134 15.185 51.627 25.152 1.00128.27 N +ATOM 29592 CA VAL P 134 14.992 51.321 23.740 1.00134.64 C +ATOM 29593 C VAL P 134 14.433 52.584 23.119 1.00134.36 C +ATOM 29594 O VAL P 134 14.728 52.929 21.968 1.00 65.94 O +ATOM 29595 CB VAL P 134 14.041 50.114 23.560 1.00127.11 C +ATOM 29596 CG1 VAL P 134 13.870 49.769 22.084 1.00118.02 C +ATOM 29597 CG2 VAL P 134 14.578 48.894 24.310 1.00160.34 C +ATOM 29598 N LYS P 135 13.627 53.284 23.917 1.00179.72 N +ATOM 29599 CA LYS P 135 13.256 54.661 23.605 1.00202.45 C +ATOM 29600 C LYS P 135 13.324 55.545 24.850 1.00164.41 C +ATOM 29601 O LYS P 135 13.220 55.070 25.984 1.00 83.14 O +ATOM 29602 CB LYS P 135 11.842 54.725 23.008 1.00241.70 C +ATOM 29603 CG LYS P 135 11.691 53.987 21.685 1.00234.58 C +ATOM 29604 CD LYS P 135 10.244 54.004 21.222 1.00209.16 C +ATOM 29605 CE LYS P 135 10.064 53.254 19.919 1.00195.73 C +ATOM 29606 NZ LYS P 135 8.818 53.686 19.242 1.00187.91 N +ATOM 29607 N SER P 136 13.440 56.846 24.610 1.00163.14 N +ATOM 29608 CA SER P 136 13.480 57.813 25.686 1.00137.24 C +ATOM 29609 C SER P 136 13.221 59.215 25.170 1.00137.24 C +ATOM 29610 O SER P 136 13.386 59.502 23.985 1.00 79.02 O +ATOM 29611 CB SER P 136 14.821 57.758 26.402 1.00124.79 C +ATOM 29612 OG SER P 136 15.455 59.022 26.409 1.00125.11 O +ATOM 29613 N GLY P 137 12.786 60.084 26.075 1.00180.96 N +ATOM 29614 CA GLY P 137 12.532 61.478 25.728 1.00215.06 C +ATOM 29615 C GLY P 137 12.379 62.381 26.940 1.00202.41 C +ATOM 29616 O GLY P 137 12.306 61.911 28.069 1.00140.43 O +ATOM 29617 N GLY P 138 12.290 63.682 26.688 1.00189.69 N +ATOM 29618 CA GLY P 138 12.041 64.642 27.749 1.00168.33 C +ATOM 29619 C GLY P 138 11.577 65.986 27.229 1.00173.16 C +ATOM 29620 O GLY P 138 11.958 66.411 26.136 1.00138.05 O +ATOM 29621 N VAL P 139 10.693 66.627 27.990 1.00189.75 N +ATOM 29622 CA VAL P 139 10.194 67.958 27.654 1.00177.47 C +ATOM 29623 C VAL P 139 10.139 68.810 28.916 1.00184.04 C +ATOM 29624 O VAL P 139 9.519 68.428 29.909 1.00169.12 O +ATOM 29625 CB VAL P 139 8.786 67.912 27.027 1.00151.76 C +ATOM 29626 CG1 VAL P 139 8.266 69.321 26.825 1.00152.01 C +ATOM 29627 CG2 VAL P 139 8.810 67.157 25.706 1.00148.22 C +ATOM 29628 N GLY P 140 10.782 69.973 28.861 1.00198.79 N +ATOM 29629 CA GLY P 140 10.826 70.879 29.999 1.00199.82 C +ATOM 29630 C GLY P 140 10.900 72.343 29.607 1.00204.14 C +ATOM 29631 O GLY P 140 11.543 72.707 28.620 1.00189.97 O +ATOM 29632 N ALA P 141 10.250 73.187 30.399 1.00197.91 N +ATOM 29633 CA ALA P 141 10.287 74.623 30.166 1.00175.82 C +ATOM 29634 C ALA P 141 10.311 75.406 31.476 1.00185.54 C +ATOM 29635 O ALA P 141 9.655 75.037 32.460 1.00129.87 O +ATOM 29636 CB ALA P 141 9.112 75.047 29.306 1.00157.01 C +ATOM 29637 N ARG P 142 11.120 76.456 31.496 1.00195.79 N +ATOM 29638 CA ARG P 142 11.133 77.368 32.618 1.00192.43 C +ATOM 29639 C ARG P 142 10.975 78.781 32.090 1.00204.92 C +ATOM 29640 O ARG P 142 11.458 79.108 31.005 1.00171.11 O +ATOM 29641 CB ARG P 142 12.416 77.225 33.443 1.00172.41 C +ATOM 29642 CG ARG P 142 12.423 78.101 34.687 1.00161.47 C +ATOM 29643 CD ARG P 142 12.967 77.390 35.915 1.00157.67 C +ATOM 29644 NE ARG P 142 14.409 77.512 36.063 1.00184.60 N +ATOM 29645 CZ ARG P 142 15.170 76.685 36.774 1.00187.66 C +ATOM 29646 NH1 ARG P 142 14.652 75.592 37.320 1.00182.25 N +ATOM 29647 NH2 ARG P 142 16.472 76.925 36.895 1.00180.54 N +ATOM 29648 N TYR P 143 10.247 79.597 32.847 1.00237.47 N +ATOM 29649 CA TYR P 143 9.868 80.936 32.414 1.00236.88 C +ATOM 29650 C TYR P 143 10.186 81.962 33.504 1.00237.72 C +ATOM 29651 O TYR P 143 9.322 82.363 34.286 1.00229.02 O +ATOM 29652 CB TYR P 143 8.379 80.965 32.057 1.00224.57 C +ATOM 29653 CG TYR P 143 7.939 82.270 31.469 1.00220.43 C +ATOM 29654 CD1 TYR P 143 8.351 82.649 30.200 1.00205.42 C +ATOM 29655 CD2 TYR P 143 7.142 83.144 32.195 1.00219.30 C +ATOM 29656 CE1 TYR P 143 7.967 83.861 29.659 1.00222.18 C +ATOM 29657 CE2 TYR P 143 6.746 84.358 31.664 1.00228.58 C +ATOM 29658 CZ TYR P 143 7.163 84.712 30.395 1.00238.88 C +ATOM 29659 OH TYR P 143 6.781 85.920 29.859 1.00258.74 O +ATOM 29660 N GLY P 145 10.919 82.311 36.092 1.00123.60 N +ATOM 29661 CA GLY P 145 10.877 81.890 37.481 1.00161.34 C +ATOM 29662 C GLY P 145 10.207 80.546 37.749 1.00194.94 C +ATOM 29663 O GLY P 145 10.555 79.885 38.731 1.00208.04 O +ATOM 29664 N ILE P 146 9.262 80.139 36.896 1.00206.49 N +ATOM 29665 CA ILE P 146 8.437 78.936 37.128 1.00200.58 C +ATOM 29666 C ILE P 146 8.751 77.882 36.057 1.00223.63 C +ATOM 29667 O ILE P 146 8.915 78.219 34.888 1.00165.46 O +ATOM 29668 CB ILE P 146 6.920 79.256 37.093 1.00170.21 C +ATOM 29669 CG1 ILE P 146 6.637 80.603 37.773 1.00160.08 C +ATOM 29670 CG2 ILE P 146 6.115 78.143 37.759 1.00141.80 C +ATOM 29671 CD1 ILE P 146 6.537 81.772 36.814 1.00132.03 C +ATOM 29672 N GLY P 147 8.878 76.614 36.449 1.00257.49 N +ATOM 29673 CA GLY P 147 9.285 75.576 35.497 1.00235.78 C +ATOM 29674 C GLY P 147 8.763 74.181 35.767 1.00238.53 C +ATOM 29675 O GLY P 147 8.451 73.823 36.902 1.00261.29 O +ATOM 29676 N ALA P 148 8.678 73.384 34.710 1.00220.42 N +ATOM 29677 CA ALA P 148 8.359 71.971 34.849 1.00201.63 C +ATOM 29678 C ALA P 148 9.068 71.160 33.773 1.00189.84 C +ATOM 29679 O ALA P 148 9.626 71.717 32.821 1.00190.75 O +ATOM 29680 CB ALA P 148 6.855 71.754 34.788 1.00170.04 C +ATOM 29681 N ASP P 149 9.097 69.848 33.966 1.00172.95 N +ATOM 29682 CA ASP P 149 9.684 68.954 32.977 1.00168.37 C +ATOM 29683 C ASP P 149 9.259 67.507 33.235 1.00179.75 C +ATOM 29684 O ASP P 149 9.012 67.113 34.377 1.00111.93 O +ATOM 29685 CB ASP P 149 11.211 69.071 32.971 1.00159.13 C +ATOM 29686 CG ASP P 149 11.852 68.281 34.075 1.00175.88 C +ATOM 29687 OD1 ASP P 149 11.784 68.726 35.236 1.00170.39 O +ATOM 29688 OD2 ASP P 149 12.413 67.213 33.779 1.00176.43 O +ATOM 29689 N THR P 150 9.100 66.742 32.161 1.00196.31 N +ATOM 29690 CA THR P 150 8.991 65.297 32.290 1.00159.63 C +ATOM 29691 C THR P 150 10.113 64.646 31.492 1.00179.92 C +ATOM 29692 O THR P 150 10.623 65.220 30.531 1.00196.47 O +ATOM 29693 CB THR P 150 7.621 64.763 31.823 1.00123.15 C +ATOM 29694 OG1 THR P 150 7.404 65.117 30.451 1.00143.35 O +ATOM 29695 CG2 THR P 150 6.499 65.315 32.672 1.00107.14 C +ATOM 29696 N GLN P 151 10.503 63.456 31.914 1.00181.41 N +ATOM 29697 CA GLN P 151 11.390 62.623 31.101 1.00164.69 C +ATOM 29698 C GLN P 151 10.863 61.183 31.167 1.00187.48 C +ATOM 29699 O GLN P 151 10.238 60.758 32.149 1.00180.83 O +ATOM 29700 CB GLN P 151 12.881 62.774 31.486 1.00165.24 C +ATOM 29701 CG GLN P 151 13.246 62.175 32.832 1.00186.67 C +ATOM 29702 CD GLN P 151 14.738 61.958 33.016 1.00191.02 C +ATOM 29703 OE1 GLN P 151 15.549 62.762 32.553 1.00213.29 O +ATOM 29704 NE2 GLN P 151 15.113 60.845 33.656 1.00182.16 N +ATOM 29705 N TYR P 152 10.968 60.476 30.058 1.00178.50 N +ATOM 29706 CA TYR P 152 10.510 59.096 30.024 1.00193.85 C +ATOM 29707 C TYR P 152 11.525 58.187 29.359 1.00239.78 C +ATOM 29708 O TYR P 152 12.243 58.611 28.454 1.00239.14 O +ATOM 29709 CB TYR P 152 9.144 58.990 29.345 1.00143.37 C +ATOM 29710 CG TYR P 152 9.127 58.449 27.935 1.00138.14 C +ATOM 29711 CD1 TYR P 152 9.747 59.127 26.882 1.00141.08 C +ATOM 29712 CD2 TYR P 152 8.418 57.296 27.635 1.00127.09 C +ATOM 29713 CE1 TYR P 152 9.738 58.612 25.583 1.00126.05 C +ATOM 29714 CE2 TYR P 152 8.360 56.800 26.335 1.00133.21 C +ATOM 29715 CZ TYR P 152 9.030 57.455 25.313 1.00123.25 C +ATOM 29716 OH TYR P 152 8.943 56.974 24.028 1.00 89.36 O +ATOM 29717 N GLN P 153 11.621 56.954 29.856 1.00237.35 N +ATOM 29718 CA GLN P 153 12.419 55.929 29.197 1.00197.59 C +ATOM 29719 C GLN P 153 11.636 54.626 29.142 1.00169.71 C +ATOM 29720 O GLN P 153 10.732 54.393 29.952 1.00106.12 O +ATOM 29721 CB GLN P 153 13.741 55.715 29.943 1.00206.73 C +ATOM 29722 CG GLN P 153 14.671 56.922 29.904 1.00202.85 C +ATOM 29723 CD GLN P 153 14.358 58.013 30.949 1.00169.97 C +ATOM 29724 OE1 GLN P 153 13.466 57.863 31.792 1.00132.38 O +ATOM 29725 NE2 GLN P 153 15.144 59.086 30.931 1.00134.11 N +ATOM 29726 N LEU P 154 11.928 53.807 28.135 1.00186.47 N +ATOM 29727 CA LEU P 154 11.317 52.478 28.072 1.00171.76 C +ATOM 29728 C LEU P 154 12.265 51.403 27.532 1.00163.31 C +ATOM 29729 O LEU P 154 13.070 51.651 26.614 1.00 92.80 O +ATOM 29730 CB LEU P 154 10.016 52.496 27.263 1.00143.31 C +ATOM 29731 CG LEU P 154 10.183 52.659 25.747 1.00196.71 C +ATOM 29732 CD1 LEU P 154 10.194 51.312 25.038 1.00194.09 C +ATOM 29733 CD2 LEU P 154 9.080 53.552 25.205 1.00248.46 C +ATOM 29734 N ASP P 155 12.070 50.201 28.072 1.00149.13 N +ATOM 29735 CA ASP P 155 12.970 49.072 27.907 1.00119.37 C +ATOM 29736 C ASP P 155 12.195 47.915 27.324 1.00 92.10 C +ATOM 29737 O ASP P 155 10.955 47.904 27.383 1.00 98.36 O +ATOM 29738 CB ASP P 155 13.534 48.662 29.271 1.00135.99 C +ATOM 29739 CG ASP P 155 14.050 49.850 30.081 1.00174.41 C +ATOM 29740 OD1 ASP P 155 13.226 50.552 30.714 1.00156.41 O +ATOM 29741 OD2 ASP P 155 15.286 50.071 30.097 1.00209.36 O +ATOM 29742 N GLN P 156 12.900 46.948 26.743 1.00 99.85 N +ATOM 29743 CA GLN P 156 12.224 45.774 26.143 1.00150.63 C +ATOM 29744 C GLN P 156 12.606 44.459 26.820 1.00156.73 C +ATOM 29745 O GLN P 156 13.607 44.385 27.519 1.00191.01 O +ATOM 29746 CB GLN P 156 12.563 45.662 24.665 1.00162.57 C +ATOM 29747 CG GLN P 156 11.707 44.666 23.900 1.00141.35 C +ATOM 29748 CD GLN P 156 11.733 44.916 22.406 1.00132.05 C +ATOM 29749 OE1 GLN P 156 12.523 45.739 21.899 1.00145.95 O +ATOM 29750 NE2 GLN P 156 10.857 44.230 21.690 1.00106.52 N +ATOM 29751 N ILE P 157 11.728 43.470 26.719 1.00119.52 N +ATOM 29752 CA ILE P 157 11.971 42.178 27.327 1.00119.51 C +ATOM 29753 C ILE P 157 11.239 41.160 26.470 1.00150.50 C +ATOM 29754 O ILE P 157 10.086 41.387 26.051 1.00268.94 O +ATOM 29755 CB ILE P 157 11.503 42.130 28.817 1.00123.77 C +ATOM 29756 CG1 ILE P 157 12.252 41.045 29.582 1.00129.07 C +ATOM 29757 CG2 ILE P 157 9.996 41.888 28.933 1.00118.21 C +ATOM 29758 CD1 ILE P 157 12.001 41.044 31.084 1.00125.74 C +ATOM 29759 N ALA P 158 11.882 40.038 26.190 1.00132.62 N +ATOM 29760 CA ALA P 158 11.240 39.029 25.352 1.00109.63 C +ATOM 29761 C ALA P 158 11.410 37.655 25.960 1.00104.96 C +ATOM 29762 O ALA P 158 12.346 37.396 26.722 1.00 68.72 O +ATOM 29763 CB ALA P 158 11.796 39.069 23.943 1.00 92.47 C +ATOM 29764 N VAL P 159 10.450 36.792 25.661 1.00108.99 N +ATOM 29765 CA VAL P 159 10.413 35.476 26.272 1.00118.41 C +ATOM 29766 C VAL P 159 10.073 34.430 25.227 1.00120.51 C +ATOM 29767 O VAL P 159 9.079 34.572 24.491 1.00172.68 O +ATOM 29768 CB VAL P 159 9.391 35.436 27.438 1.00120.80 C +ATOM 29769 CG1 VAL P 159 8.966 34.012 27.753 1.00117.38 C +ATOM 29770 CG2 VAL P 159 9.991 36.083 28.679 1.00126.42 C +ATOM 29771 N ASN P 160 10.903 33.392 25.160 1.00 80.23 N +ATOM 29772 CA ASN P 160 10.577 32.208 24.386 1.00 74.82 C +ATOM 29773 C ASN P 160 9.941 31.175 25.312 1.00 77.51 C +ATOM 29774 O ASN P 160 10.452 30.899 26.417 1.00 87.34 O +ATOM 29775 CB ASN P 160 11.851 31.659 23.767 1.00 62.72 C +ATOM 29776 CG ASN P 160 11.647 30.358 22.995 1.00 63.23 C +ATOM 29777 OD1 ASN P 160 11.014 29.391 23.476 1.00 63.01 O +ATOM 29778 ND2 ASN P 160 12.306 30.267 21.844 1.00 51.46 N +ATOM 29779 N LEU P 161 8.805 30.629 24.892 1.00 57.00 N +ATOM 29780 CA LEU P 161 8.334 29.394 25.471 1.00 58.79 C +ATOM 29781 C LEU P 161 8.206 28.383 24.372 1.00 56.72 C +ATOM 29782 O LEU P 161 7.760 28.712 23.274 1.00 89.22 O +ATOM 29783 CB LEU P 161 7.003 29.612 26.208 1.00 64.35 C +ATOM 29784 CG LEU P 161 7.053 30.500 27.429 1.00 73.77 C +ATOM 29785 CD1 LEU P 161 5.652 30.795 27.941 1.00 86.50 C +ATOM 29786 CD2 LEU P 161 7.894 29.841 28.519 1.00 80.54 C +ATOM 29787 N ARG P 162 8.372 27.114 24.705 1.00 70.04 N +ATOM 29788 CA ARG P 162 8.141 26.076 23.701 1.00 98.17 C +ATOM 29789 C ARG P 162 7.754 24.680 24.247 1.00 72.27 C +ATOM 29790 O ARG P 162 8.337 24.190 25.192 1.00 79.82 O +ATOM 29791 CB ARG P 162 9.362 25.989 22.785 1.00115.03 C +ATOM 29792 CG ARG P 162 10.669 25.569 23.446 1.00129.60 C +ATOM 29793 CD ARG P 162 11.669 25.139 22.375 1.00127.46 C +ATOM 29794 NE ARG P 162 12.897 24.519 22.891 1.00 95.71 N +ATOM 29795 CZ ARG P 162 13.945 25.186 23.340 1.00 80.05 C +ATOM 29796 NH1 ARG P 162 13.890 26.513 23.448 1.00102.95 N +ATOM 29797 NH2 ARG P 162 15.028 24.525 23.715 1.00 64.26 N +ATOM 29798 N VAL P 163 6.745 24.083 23.624 1.00 61.56 N +ATOM 29799 CA VAL P 163 6.234 22.786 24.008 1.00 57.28 C +ATOM 29800 C VAL P 163 7.065 21.787 23.290 1.00 52.25 C +ATOM 29801 O VAL P 163 7.009 21.702 22.060 1.00 63.51 O +ATOM 29802 CB VAL P 163 4.759 22.588 23.564 1.00 78.28 C +ATOM 29803 CG1 VAL P 163 4.278 21.187 23.928 1.00 75.10 C +ATOM 29804 CG2 VAL P 163 3.851 23.669 24.184 1.00112.18 C +ATOM 29805 N VAL P 164 7.637 20.887 24.073 1.00 62.10 N +ATOM 29806 CA VAL P 164 8.379 19.731 23.569 1.00 76.90 C +ATOM 29807 C VAL P 164 7.697 18.406 23.891 1.00 74.32 C +ATOM 29808 O VAL P 164 7.140 18.233 24.970 1.00 58.86 O +ATOM 29809 CB VAL P 164 9.741 19.633 24.221 1.00 67.68 C +ATOM 29810 CG1 VAL P 164 10.478 18.439 23.668 1.00 75.72 C +ATOM 29811 CG2 VAL P 164 10.493 20.893 23.925 1.00 89.30 C +ATOM 29812 N ASN P 165 7.598 17.549 22.874 1.00 78.97 N +ATOM 29813 CA ASN P 165 6.895 16.279 23.012 1.00 84.75 C +ATOM 29814 C ASN P 165 7.872 15.259 23.590 1.00 84.85 C +ATOM 29815 O ASN P 165 8.876 14.947 22.955 1.00 78.77 O +ATOM 29816 CB ASN P 165 6.312 15.782 21.666 1.00 70.01 C +ATOM 29817 CG ASN P 165 5.373 14.610 21.853 1.00 74.56 C +ATOM 29818 OD1 ASN P 165 5.114 14.194 22.994 1.00 86.19 O +ATOM 29819 ND2 ASN P 165 5.082 13.922 20.776 1.00 92.64 N +ATOM 29820 N VAL P 166 7.535 14.724 24.762 1.00 75.78 N +ATOM 29821 CA VAL P 166 8.403 13.804 25.479 1.00 60.46 C +ATOM 29822 C VAL P 166 8.610 12.580 24.673 1.00 49.93 C +ATOM 29823 O VAL P 166 9.699 12.059 24.598 1.00 45.59 O +ATOM 29824 CB VAL P 166 7.782 13.420 26.835 1.00 71.32 C +ATOM 29825 CG1 VAL P 166 8.285 12.066 27.307 1.00 62.79 C +ATOM 29826 CG2 VAL P 166 8.043 14.543 27.875 1.00 79.55 C +ATOM 29827 N SER P 167 7.554 12.153 24.012 1.00 64.68 N +ATOM 29828 CA SER P 167 7.574 10.893 23.288 1.00 92.17 C +ATOM 29829 C SER P 167 8.470 10.905 22.044 1.00 75.33 C +ATOM 29830 O SER P 167 8.736 9.834 21.479 1.00 61.64 O +ATOM 29831 CB SER P 167 6.137 10.487 22.920 1.00114.06 C +ATOM 29832 OG SER P 167 5.274 10.675 24.026 1.00151.85 O +ATOM 29833 N THR P 168 8.907 12.090 21.609 1.00 63.38 N +ATOM 29834 CA THR P 168 9.659 12.203 20.357 1.00 72.92 C +ATOM 29835 C THR P 168 10.812 13.187 20.406 1.00 54.50 C +ATOM 29836 O THR P 168 11.841 13.021 19.745 1.00 58.00 O +ATOM 29837 CB THR P 168 8.755 12.605 19.163 1.00 81.64 C +ATOM 29838 OG1 THR P 168 8.003 13.772 19.495 1.00104.69 O +ATOM 29839 CG2 THR P 168 7.792 11.461 18.762 1.00 76.24 C +ATOM 29840 N GLY P 169 10.624 14.242 21.145 1.00 50.01 N +ATOM 29841 CA GLY P 169 11.601 15.283 21.107 1.00 68.07 C +ATOM 29842 C GLY P 169 11.329 16.285 20.011 1.00 88.53 C +ATOM 29843 O GLY P 169 11.848 17.422 20.093 1.00182.51 O +ATOM 29844 N GLU P 170 10.369 15.996 19.127 1.00 78.00 N +ATOM 29845 CA GLU P 170 9.699 17.082 18.358 1.00101.19 C +ATOM 29846 C GLU P 170 9.214 18.262 19.239 1.00 80.00 C +ATOM 29847 O GLU P 170 8.524 18.073 20.220 1.00 83.04 O +ATOM 29848 CB GLU P 170 8.481 16.573 17.560 1.00105.79 C +ATOM 29849 CG GLU P 170 8.857 15.709 16.362 1.00119.59 C +ATOM 29850 CD GLU P 170 7.884 14.577 16.088 1.00119.59 C +ATOM 29851 OE1 GLU P 170 7.039 14.283 16.969 1.00138.30 O +ATOM 29852 OE2 GLU P 170 8.052 13.885 15.060 1.00124.27 O +ATOM 29853 N ILE P 171 9.689 19.457 18.959 1.00 60.36 N +ATOM 29854 CA ILE P 171 9.076 20.601 19.509 1.00 67.31 C +ATOM 29855 C ILE P 171 7.683 20.729 18.861 1.00112.95 C +ATOM 29856 O ILE P 171 7.554 20.783 17.628 1.00192.33 O +ATOM 29857 CB ILE P 171 9.924 21.819 19.230 1.00 59.37 C +ATOM 29858 CG1 ILE P 171 11.156 21.747 20.087 1.00 59.06 C +ATOM 29859 CG2 ILE P 171 9.119 23.080 19.525 1.00 86.23 C +ATOM 29860 CD1 ILE P 171 12.227 22.711 19.625 1.00 97.72 C +ATOM 29861 N LEU P 172 6.638 20.828 19.677 1.00131.23 N +ATOM 29862 CA LEU P 172 5.274 20.925 19.154 1.00116.40 C +ATOM 29863 C LEU P 172 4.767 22.374 18.987 1.00105.40 C +ATOM 29864 O LEU P 172 3.745 22.654 18.314 1.00123.39 O +ATOM 29865 CB LEU P 172 4.310 20.155 20.048 1.00114.92 C +ATOM 29866 CG LEU P 172 4.505 18.620 19.997 1.00141.76 C +ATOM 29867 CD1 LEU P 172 3.471 17.769 20.757 1.00126.39 C +ATOM 29868 CD2 LEU P 172 4.697 18.097 18.575 1.00166.53 C +ATOM 29869 N SER P 173 5.486 23.300 19.594 1.00 90.11 N +ATOM 29870 CA SER P 173 5.159 24.709 19.468 1.00108.37 C +ATOM 29871 C SER P 173 6.272 25.593 20.023 1.00110.43 C +ATOM 29872 O SER P 173 6.759 25.365 21.131 1.00178.60 O +ATOM 29873 CB SER P 173 3.880 25.000 20.239 1.00120.34 C +ATOM 29874 OG SER P 173 3.723 26.389 20.433 1.00168.41 O +ATOM 29875 N SER P 174 6.677 26.601 19.264 1.00 84.88 N +ATOM 29876 CA SER P 174 7.547 27.633 19.799 1.00 91.37 C +ATOM 29877 C SER P 174 6.823 28.977 19.685 1.00 98.12 C +ATOM 29878 O SER P 174 6.245 29.285 18.645 1.00157.51 O +ATOM 29879 CB SER P 174 8.903 27.663 19.050 1.00 69.32 C +ATOM 29880 OG SER P 174 9.857 28.502 19.692 1.00 76.39 O +ATOM 29881 N VAL P 175 6.894 29.794 20.735 1.00 74.36 N +ATOM 29882 CA VAL P 175 6.328 31.132 20.713 1.00 76.83 C +ATOM 29883 C VAL P 175 7.274 32.167 21.290 1.00 77.46 C +ATOM 29884 O VAL P 175 7.983 31.917 22.262 1.00 59.78 O +ATOM 29885 CB VAL P 175 4.981 31.181 21.479 1.00111.60 C +ATOM 29886 CG1 VAL P 175 3.953 30.273 20.808 1.00132.36 C +ATOM 29887 CG2 VAL P 175 5.158 30.756 22.916 1.00118.04 C +ATOM 29888 N ASN P 176 7.207 33.380 20.737 1.00119.99 N +ATOM 29889 CA ASN P 176 8.130 34.476 21.100 1.00130.49 C +ATOM 29890 C ASN P 176 7.416 35.775 21.516 1.00103.57 C +ATOM 29891 O ASN P 176 7.095 36.577 20.659 1.00 99.27 O +ATOM 29892 CB ASN P 176 9.040 34.760 19.888 1.00119.63 C +ATOM 29893 CG ASN P 176 10.404 34.076 19.984 1.00142.94 C +ATOM 29894 OD1 ASN P 176 11.358 34.357 19.203 1.00107.61 O +ATOM 29895 ND2 ASN P 176 10.501 33.145 20.934 1.00150.74 N +ATOM 29896 N THR P 177 7.174 35.980 22.816 1.00 94.09 N +ATOM 29897 CA THR P 177 6.419 37.156 23.291 1.00 84.36 C +ATOM 29898 C THR P 177 7.366 38.265 23.716 1.00111.50 C +ATOM 29899 O THR P 177 8.547 38.015 24.002 1.00116.06 O +ATOM 29900 CB THR P 177 5.472 36.821 24.459 1.00 64.38 C +ATOM 29901 OG1 THR P 177 6.242 36.496 25.618 1.00 77.43 O +ATOM 29902 CG2 THR P 177 4.590 35.620 24.109 1.00 62.65 C +ATOM 29903 N SER P 178 6.838 39.485 23.763 1.00124.04 N +ATOM 29904 CA SER P 178 7.639 40.674 24.085 1.00147.88 C +ATOM 29905 C SER P 178 6.805 41.734 24.815 1.00130.04 C +ATOM 29906 O SER P 178 5.598 41.777 24.707 1.00 83.00 O +ATOM 29907 CB SER P 178 8.223 41.314 22.822 1.00142.82 C +ATOM 29908 OG SER P 178 8.731 42.622 23.100 1.00 90.52 O +ATOM 29909 N LYS P 179 7.480 42.575 25.586 1.00138.57 N +ATOM 29910 CA LYS P 179 6.785 43.477 26.484 1.00101.22 C +ATOM 29911 C LYS P 179 7.700 44.648 26.814 1.00122.53 C +ATOM 29912 O LYS P 179 8.931 44.504 26.971 1.00140.26 O +ATOM 29913 CB LYS P 179 6.349 42.734 27.756 1.00 99.97 C +ATOM 29914 CG LYS P 179 5.015 43.165 28.310 1.00 73.62 C +ATOM 29915 CD LYS P 179 5.229 44.222 29.370 1.00101.22 C +ATOM 29916 CE LYS P 179 3.902 44.800 29.818 1.00118.02 C +ATOM 29917 NZ LYS P 179 4.083 46.042 30.617 1.00130.02 N +ATOM 29918 N THR P 180 7.084 45.810 26.942 1.00129.25 N +ATOM 29919 CA THR P 180 7.819 47.042 27.159 1.00146.92 C +ATOM 29920 C THR P 180 7.653 47.551 28.602 1.00161.12 C +ATOM 29921 O THR P 180 6.546 47.585 29.151 1.00117.88 O +ATOM 29922 CB THR P 180 7.405 48.137 26.155 1.00143.04 C +ATOM 29923 OG1 THR P 180 7.692 49.425 26.705 1.00143.66 O +ATOM 29924 CG2 THR P 180 5.927 48.033 25.818 1.00140.49 C +ATOM 29925 N ILE P 181 8.778 47.896 29.220 1.00169.97 N +ATOM 29926 CA ILE P 181 8.774 48.422 30.571 1.00146.73 C +ATOM 29927 C ILE P 181 8.835 49.954 30.510 1.00161.45 C +ATOM 29928 O ILE P 181 9.861 50.528 30.087 1.00216.13 O +ATOM 29929 CB ILE P 181 9.951 47.835 31.396 1.00127.47 C +ATOM 29930 CG1 ILE P 181 9.930 46.314 31.337 1.00 93.07 C +ATOM 29931 CG2 ILE P 181 9.879 48.262 32.857 1.00148.48 C +ATOM 29932 CD1 ILE P 181 11.180 45.740 30.729 1.00116.40 C +ATOM 29933 N LEU P 182 7.781 50.604 31.017 1.00116.20 N +ATOM 29934 CA LEU P 182 7.713 52.072 31.078 1.00132.88 C +ATOM 29935 C LEU P 182 8.273 52.744 32.365 1.00157.17 C +ATOM 29936 O LEU P 182 8.031 52.286 33.490 1.00142.34 O +ATOM 29937 CB LEU P 182 6.274 52.502 30.916 1.00105.80 C +ATOM 29938 CG LEU P 182 6.041 54.009 30.920 1.00109.02 C +ATOM 29939 CD1 LEU P 182 6.750 54.746 29.777 1.00 96.41 C +ATOM 29940 CD2 LEU P 182 4.545 54.241 30.879 1.00129.02 C +ATOM 29941 N SER P 183 9.007 53.848 32.180 1.00162.87 N +ATOM 29942 CA SER P 183 9.491 54.669 33.291 1.00150.76 C +ATOM 29943 C SER P 183 9.349 56.155 32.961 1.00169.32 C +ATOM 29944 O SER P 183 9.551 56.567 31.815 1.00139.11 O +ATOM 29945 CB SER P 183 10.954 54.368 33.581 1.00143.28 C +ATOM 29946 OG SER P 183 11.226 52.994 33.430 1.00159.14 O +ATOM 29947 N TYR P 184 8.948 56.950 33.953 1.00180.41 N +ATOM 29948 CA TYR P 184 8.847 58.390 33.764 1.00143.62 C +ATOM 29949 C TYR P 184 9.092 59.193 35.044 1.00150.23 C +ATOM 29950 O TYR P 184 8.828 58.742 36.170 1.00 90.49 O +ATOM 29951 CB TYR P 184 7.507 58.767 33.111 1.00130.44 C +ATOM 29952 CG TYR P 184 6.285 58.328 33.895 1.00127.04 C +ATOM 29953 CD1 TYR P 184 5.763 59.122 34.902 1.00152.38 C +ATOM 29954 CD2 TYR P 184 5.632 57.141 33.597 1.00114.10 C +ATOM 29955 CE1 TYR P 184 4.636 58.736 35.598 1.00149.03 C +ATOM 29956 CE2 TYR P 184 4.495 56.753 34.275 1.00113.37 C +ATOM 29957 CZ TYR P 184 4.009 57.548 35.280 1.00140.48 C +ATOM 29958 OH TYR P 184 2.906 57.144 35.987 1.00178.28 O +ATOM 29959 N GLU P 185 9.535 60.427 34.831 1.00182.86 N +ATOM 29960 CA GLU P 185 9.833 61.375 35.904 1.00205.52 C +ATOM 29961 C GLU P 185 9.216 62.748 35.629 1.00211.90 C +ATOM 29962 O GLU P 185 9.628 63.438 34.705 1.00191.55 O +ATOM 29963 CB GLU P 185 11.337 61.556 36.099 1.00174.11 C +ATOM 29964 CG GLU P 185 12.167 60.295 36.020 1.00144.06 C +ATOM 29965 CD GLU P 185 13.597 60.563 36.433 1.00169.69 C +ATOM 29966 OE1 GLU P 185 13.939 61.744 36.719 1.00203.32 O +ATOM 29967 OE2 GLU P 185 14.381 59.599 36.481 1.00205.19 O +ATOM 29968 N VAL P 186 8.241 63.128 36.449 1.00183.28 N +ATOM 29969 CA VAL P 186 7.605 64.426 36.366 1.00174.28 C +ATOM 29970 C VAL P 186 8.163 65.335 37.459 1.00199.15 C +ATOM 29971 O VAL P 186 8.352 64.904 38.594 1.00191.07 O +ATOM 29972 CB VAL P 186 6.075 64.299 36.510 1.00156.85 C +ATOM 29973 CG1 VAL P 186 5.405 65.628 36.216 1.00156.41 C +ATOM 29974 CG2 VAL P 186 5.540 63.225 35.574 1.00160.11 C +ATOM 29975 N GLN P 187 8.422 66.593 37.109 1.00209.49 N +ATOM 29976 CA GLN P 187 9.011 67.540 38.053 1.00179.29 C +ATOM 29977 C GLN P 187 8.512 68.948 37.799 1.00170.84 C +ATOM 29978 O GLN P 187 8.430 69.387 36.649 1.00147.92 O +ATOM 29979 CB GLN P 187 10.533 67.520 37.912 1.00161.78 C +ATOM 29980 CG GLN P 187 11.238 66.451 38.720 1.00174.22 C +ATOM 29981 CD GLN P 187 12.620 66.149 38.180 1.00204.99 C +ATOM 29982 OE1 GLN P 187 13.328 67.053 37.731 1.00209.46 O +ATOM 29983 NE2 GLN P 187 13.006 64.865 38.192 1.00204.29 N +ATOM 29984 N ALA P 188 8.218 69.668 38.874 1.00178.46 N +ATOM 29985 CA ALA P 188 7.825 71.068 38.762 1.00195.61 C +ATOM 29986 C ALA P 188 8.440 71.895 39.888 1.00205.43 C +ATOM 29987 O ALA P 188 8.533 71.428 41.013 1.00191.19 O +ATOM 29988 CB ALA P 188 6.311 71.185 38.762 1.00166.67 C +ATOM 29989 N GLY P 189 8.900 73.103 39.567 1.00185.02 N +ATOM 29990 CA GLY P 189 9.549 73.967 40.545 1.00179.19 C +ATOM 29991 C GLY P 189 9.242 75.439 40.343 1.00189.95 C +ATOM 29992 O GLY P 189 9.198 75.921 39.215 1.00201.43 O +ATOM 29993 N VAL P 190 8.988 76.147 41.441 1.00223.16 N +ATOM 29994 CA VAL P 190 8.712 77.579 41.397 1.00220.00 C +ATOM 29995 C VAL P 190 9.833 78.337 42.117 1.00212.69 C +ATOM 29996 O VAL P 190 10.268 77.936 43.205 1.00242.11 O +ATOM 29997 CB VAL P 190 7.347 77.910 42.042 1.00211.47 C +ATOM 29998 CG1 VAL P 190 6.970 79.355 41.761 1.00216.84 C +ATOM 29999 CG2 VAL P 190 6.263 76.959 41.540 1.00188.23 C +ATOM 30000 N PHE P 191 10.309 79.420 41.506 1.00185.86 N +ATOM 30001 CA PHE P 191 11.496 80.119 42.006 1.00197.02 C +ATOM 30002 C PHE P 191 11.252 81.626 42.063 1.00184.72 C +ATOM 30003 O PHE P 191 10.775 82.210 41.087 1.00229.81 O +ATOM 30004 CB PHE P 191 12.702 79.792 41.111 1.00187.40 C +ATOM 30005 CG PHE P 191 14.036 80.019 41.770 1.00224.02 C +ATOM 30006 CD1 PHE P 191 14.505 81.307 41.996 1.00223.11 C +ATOM 30007 CD2 PHE P 191 14.830 78.945 42.157 1.00220.22 C +ATOM 30008 CE1 PHE P 191 15.735 81.521 42.599 1.00194.92 C +ATOM 30009 CE2 PHE P 191 16.053 79.152 42.772 1.00204.85 C +ATOM 30010 CZ PHE P 191 16.511 80.443 42.984 1.00182.95 C +ATOM 30011 N LEU P 200 12.005 82.831 47.565 1.00227.11 N +ATOM 30012 CA LEU P 200 11.062 81.720 47.462 1.00201.88 C +ATOM 30013 C LEU P 200 11.515 80.691 46.435 1.00205.41 C +ATOM 30014 O LEU P 200 11.563 80.982 45.236 1.00142.07 O +ATOM 30015 CB LEU P 200 9.674 82.227 47.071 1.00177.28 C +ATOM 30016 CG LEU P 200 8.665 81.116 46.731 1.00160.67 C +ATOM 30017 CD1 LEU P 200 7.731 80.873 47.909 1.00137.17 C +ATOM 30018 CD2 LEU P 200 7.889 81.401 45.443 1.00149.35 C +ATOM 30019 N GLU P 201 11.824 79.487 46.917 1.00214.76 N +ATOM 30020 CA GLU P 201 11.887 78.308 46.066 1.00206.79 C +ATOM 30021 C GLU P 201 10.891 77.256 46.543 1.00203.32 C +ATOM 30022 O GLU P 201 10.618 77.148 47.737 1.00195.97 O +ATOM 30023 CB GLU P 201 13.294 77.715 46.056 1.00203.81 C +ATOM 30024 CG GLU P 201 13.543 76.808 44.863 1.00214.39 C +ATOM 30025 CD GLU P 201 14.941 76.213 44.843 1.00219.40 C +ATOM 30026 OE1 GLU P 201 15.922 76.976 44.975 1.00202.32 O +ATOM 30027 OE2 GLU P 201 15.056 74.978 44.674 1.00213.80 O +ATOM 30028 N GLY P 202 10.345 76.491 45.602 1.00203.02 N +ATOM 30029 CA GLY P 202 9.488 75.352 45.924 1.00196.66 C +ATOM 30030 C GLY P 202 9.530 74.314 44.816 1.00189.08 C +ATOM 30031 O GLY P 202 9.256 74.639 43.661 1.00243.79 O +ATOM 30032 N GLU P 203 9.818 73.061 45.165 1.00161.54 N +ATOM 30033 CA GLU P 203 9.863 71.988 44.162 1.00149.01 C +ATOM 30034 C GLU P 203 8.958 70.772 44.539 1.00161.16 C +ATOM 30035 O GLU P 203 8.867 70.348 45.705 1.00134.57 O +ATOM 30036 CB GLU P 203 11.336 71.575 43.849 1.00144.99 C +ATOM 30037 CG GLU P 203 11.495 70.245 43.090 1.00154.80 C +ATOM 30038 CD GLU P 203 12.911 69.657 43.102 1.00146.32 C +ATOM 30039 OE1 GLU P 203 13.859 70.364 43.519 1.00184.68 O +ATOM 30040 OE2 GLU P 203 13.083 68.485 42.661 1.00104.89 O +ATOM 30041 N VAL P 204 8.267 70.245 43.526 1.00176.66 N +ATOM 30042 CA VAL P 204 7.559 68.961 43.599 1.00184.21 C +ATOM 30043 C VAL P 204 8.100 68.017 42.517 1.00197.73 C +ATOM 30044 O VAL P 204 8.340 68.437 41.384 1.00146.14 O +ATOM 30045 CB VAL P 204 6.035 69.145 43.422 1.00156.39 C +ATOM 30046 CG1 VAL P 204 5.336 67.820 43.124 1.00146.79 C +ATOM 30047 CG2 VAL P 204 5.447 69.784 44.667 1.00145.40 C +ATOM 30048 N GLY P 205 8.350 66.765 42.901 1.00197.45 N +ATOM 30049 CA GLY P 205 8.813 65.748 41.967 1.00156.06 C +ATOM 30050 C GLY P 205 8.100 64.418 42.156 1.00151.29 C +ATOM 30051 O GLY P 205 7.659 64.087 43.260 1.00136.43 O +ATOM 30052 N TYR P 206 7.965 63.662 41.069 1.00146.96 N +ATOM 30053 CA TYR P 206 7.394 62.309 41.112 1.00138.05 C +ATOM 30054 C TYR P 206 8.032 61.426 40.044 1.00138.12 C +ATOM 30055 O TYR P 206 8.296 61.887 38.948 1.00125.07 O +ATOM 30056 CB TYR P 206 5.883 62.347 40.885 1.00116.28 C +ATOM 30057 CG TYR P 206 5.229 60.981 40.845 1.00 91.36 C +ATOM 30058 CD1 TYR P 206 4.930 60.297 42.025 1.00 92.40 C +ATOM 30059 CD2 TYR P 206 4.871 60.389 39.629 1.00 75.15 C +ATOM 30060 CE1 TYR P 206 4.296 59.059 41.994 1.00 96.79 C +ATOM 30061 CE2 TYR P 206 4.225 59.165 39.583 1.00 74.34 C +ATOM 30062 CZ TYR P 206 3.952 58.491 40.763 1.00 96.67 C +ATOM 30063 OH TYR P 206 3.383 57.232 40.710 1.00 93.57 O +ATOM 30064 N THR P 207 8.298 60.162 40.374 1.00133.66 N +ATOM 30065 CA THR P 207 8.889 59.220 39.415 1.00118.28 C +ATOM 30066 C THR P 207 8.203 57.852 39.508 1.00132.02 C +ATOM 30067 O THR P 207 7.936 57.343 40.611 1.00109.72 O +ATOM 30068 CB THR P 207 10.407 59.039 39.642 1.00 97.12 C +ATOM 30069 OG1 THR P 207 10.628 58.491 40.947 1.00124.81 O +ATOM 30070 CG2 THR P 207 11.132 60.347 39.532 1.00 80.20 C +ATOM 30071 N SER P 208 7.910 57.254 38.355 1.00146.67 N +ATOM 30072 CA SER P 208 7.282 55.927 38.334 1.00170.15 C +ATOM 30073 C SER P 208 7.962 54.967 37.356 1.00201.75 C +ATOM 30074 O SER P 208 8.114 55.274 36.174 1.00153.71 O +ATOM 30075 CB SER P 208 5.795 56.030 38.003 1.00169.32 C +ATOM 30076 OG SER P 208 5.222 54.736 37.850 1.00125.29 O +ATOM 30077 N ASN P 209 8.364 53.808 37.876 1.00209.43 N +ATOM 30078 CA ASN P 209 8.908 52.716 37.071 1.00149.64 C +ATOM 30079 C ASN P 209 7.973 51.536 37.100 1.00179.74 C +ATOM 30080 O ASN P 209 7.451 51.170 38.153 1.00202.33 O +ATOM 30081 CB ASN P 209 10.241 52.260 37.623 1.00112.39 C +ATOM 30082 CG ASN P 209 11.312 53.287 37.416 1.00 97.93 C +ATOM 30083 OD1 ASN P 209 11.933 53.343 36.368 1.00 70.02 O +ATOM 30084 ND2 ASN P 209 11.595 54.055 38.458 1.00112.15 N +ATOM 30085 N GLU P 210 7.758 50.936 35.940 1.00180.12 N +ATOM 30086 CA GLU P 210 7.093 49.646 35.903 1.00139.74 C +ATOM 30087 C GLU P 210 8.023 48.635 36.556 1.00 98.49 C +ATOM 30088 O GLU P 210 9.244 48.673 36.357 1.00113.53 O +ATOM 30089 CB GLU P 210 6.785 49.250 34.451 1.00192.44 C +ATOM 30090 CG GLU P 210 5.398 48.672 34.222 1.00192.48 C +ATOM 30091 CD GLU P 210 4.988 48.700 32.749 1.00193.04 C +ATOM 30092 OE1 GLU P 210 5.482 49.557 31.958 1.00111.23 O +ATOM 30093 OE2 GLU P 210 4.162 47.837 32.388 1.00216.31 O +ATOM 30094 N PRO P 211 7.461 47.702 37.303 1.00 80.55 N +ATOM 30095 CA PRO P 211 8.260 46.579 37.750 1.00 99.52 C +ATOM 30096 C PRO P 211 8.616 45.591 36.626 1.00110.50 C +ATOM 30097 O PRO P 211 7.734 45.092 35.933 1.00 83.71 O +ATOM 30098 CB PRO P 211 7.371 45.900 38.796 1.00 95.85 C +ATOM 30099 CG PRO P 211 6.349 46.908 39.143 1.00108.23 C +ATOM 30100 CD PRO P 211 6.123 47.670 37.873 1.00103.00 C +ATOM 30101 N VAL P 212 9.920 45.348 36.441 1.00125.71 N +ATOM 30102 CA VAL P 212 10.423 44.410 35.432 1.00 90.99 C +ATOM 30103 C VAL P 212 9.939 43.003 35.771 1.00 80.36 C +ATOM 30104 O VAL P 212 9.478 42.254 34.906 1.00 98.10 O +ATOM 30105 CB VAL P 212 11.962 44.385 35.390 1.00 87.05 C +ATOM 30106 CG1 VAL P 212 12.434 43.498 34.247 1.00120.23 C +ATOM 30107 CG2 VAL P 212 12.540 45.792 35.253 1.00 76.92 C +ATOM 30108 N MET P 213 10.018 42.692 37.050 1.00 70.23 N +ATOM 30109 CA MET P 213 9.293 41.607 37.674 1.00102.57 C +ATOM 30110 C MET P 213 7.898 41.327 37.053 1.00133.12 C +ATOM 30111 O MET P 213 7.551 40.180 36.698 1.00169.16 O +ATOM 30112 CB MET P 213 9.161 42.012 39.155 1.00109.90 C +ATOM 30113 CG MET P 213 8.570 41.013 40.122 1.00133.78 C +ATOM 30114 SD MET P 213 8.602 41.761 41.759 1.00113.09 S +ATOM 30115 CE MET P 213 6.831 42.006 41.905 1.00162.39 C +ATOM 30116 N LEU P 214 7.094 42.378 36.958 1.00132.12 N +ATOM 30117 CA LEU P 214 5.666 42.246 36.701 1.00123.06 C +ATOM 30118 C LEU P 214 5.456 42.128 35.198 1.00 83.29 C +ATOM 30119 O LEU P 214 4.498 41.509 34.733 1.00 92.65 O +ATOM 30120 CB LEU P 214 4.915 43.462 37.276 1.00132.45 C +ATOM 30121 CG LEU P 214 3.575 43.242 38.003 1.00136.41 C +ATOM 30122 CD1 LEU P 214 3.719 42.332 39.217 1.00122.28 C +ATOM 30123 CD2 LEU P 214 2.993 44.590 38.412 1.00144.99 C +ATOM 30124 N CYS P 215 6.344 42.755 34.445 1.00 58.85 N +ATOM 30125 CA CYS P 215 6.313 42.670 32.989 1.00 71.28 C +ATOM 30126 C CYS P 215 6.691 41.254 32.530 1.00 96.34 C +ATOM 30127 O CYS P 215 6.138 40.709 31.547 1.00 96.58 O +ATOM 30128 CB CYS P 215 7.289 43.677 32.369 1.00 66.66 C +ATOM 30129 SG CYS P 215 6.846 45.371 32.699 1.00110.82 S +ATOM 30130 N LEU P 216 7.713 40.705 33.188 1.00119.33 N +ATOM 30131 CA LEU P 216 8.140 39.346 32.922 1.00100.48 C +ATOM 30132 C LEU P 216 6.929 38.420 33.128 1.00 90.71 C +ATOM 30133 O LEU P 216 6.634 37.588 32.262 1.00104.60 O +ATOM 30134 CB LEU P 216 9.325 38.957 33.830 1.00 71.26 C +ATOM 30135 CG LEU P 216 9.802 37.518 33.667 1.00 65.08 C +ATOM 30136 CD1 LEU P 216 10.243 37.184 32.235 1.00 71.75 C +ATOM 30137 CD2 LEU P 216 10.940 37.240 34.603 1.00 67.99 C +ATOM 30138 N MET P 217 6.230 38.603 34.246 1.00 63.67 N +ATOM 30139 CA MET P 217 5.153 37.714 34.601 1.00 51.37 C +ATOM 30140 C MET P 217 4.068 37.826 33.566 1.00 65.18 C +ATOM 30141 O MET P 217 3.561 36.821 33.068 1.00 69.92 O +ATOM 30142 CB MET P 217 4.634 38.061 35.972 1.00 57.03 C +ATOM 30143 CG MET P 217 4.345 36.836 36.821 1.00 76.78 C +ATOM 30144 SD MET P 217 2.917 35.899 36.231 1.00115.77 S +ATOM 30145 CE MET P 217 2.982 34.398 37.220 1.00122.74 C +ATOM 30146 N SER P 218 3.730 39.066 33.186 1.00110.13 N +ATOM 30147 CA SER P 218 2.679 39.353 32.162 1.00 95.22 C +ATOM 30148 C SER P 218 2.983 38.692 30.824 1.00 95.51 C +ATOM 30149 O SER P 218 2.151 37.934 30.293 1.00 98.17 O +ATOM 30150 CB SER P 218 2.562 40.849 31.927 1.00 74.77 C +ATOM 30151 OG SER P 218 1.444 41.137 31.142 1.00 80.01 O +ATOM 30152 N ALA P 219 4.218 38.876 30.355 1.00 94.98 N +ATOM 30153 CA ALA P 219 4.648 38.280 29.096 1.00115.00 C +ATOM 30154 C ALA P 219 4.632 36.716 29.092 1.00103.83 C +ATOM 30155 O ALA P 219 4.271 36.084 28.081 1.00 68.88 O +ATOM 30156 CB ALA P 219 6.027 38.799 28.734 1.00108.89 C +ATOM 30157 N ILE P 220 4.987 36.105 30.221 1.00 74.51 N +ATOM 30158 CA ILE P 220 4.937 34.660 30.330 1.00 77.48 C +ATOM 30159 C ILE P 220 3.496 34.132 30.261 1.00112.13 C +ATOM 30160 O ILE P 220 3.214 33.131 29.595 1.00126.34 O +ATOM 30161 CB ILE P 220 5.598 34.182 31.621 1.00 80.27 C +ATOM 30162 CG1 ILE P 220 7.110 34.426 31.530 1.00 99.53 C +ATOM 30163 CG2 ILE P 220 5.295 32.703 31.885 1.00 66.88 C +ATOM 30164 CD1 ILE P 220 7.834 34.362 32.865 1.00136.05 C +ATOM 30165 N GLU P 221 2.569 34.824 30.920 1.00169.82 N +ATOM 30166 CA GLU P 221 1.132 34.478 30.844 1.00167.55 C +ATOM 30167 C GLU P 221 0.635 34.505 29.397 1.00130.30 C +ATOM 30168 O GLU P 221 0.056 33.529 28.904 1.00101.77 O +ATOM 30169 CB GLU P 221 0.295 35.452 31.691 1.00171.47 C +ATOM 30170 CG GLU P 221 0.422 35.230 33.189 1.00169.31 C +ATOM 30171 CD GLU P 221 -0.086 36.406 34.008 1.00151.58 C +ATOM 30172 OE1 GLU P 221 0.162 37.584 33.626 1.00119.97 O +ATOM 30173 OE2 GLU P 221 -0.582 36.137 35.122 1.00135.10 O +ATOM 30174 N THR P 222 0.915 35.620 28.726 1.00104.84 N +ATOM 30175 CA THR P 222 0.598 35.801 27.315 1.00 97.09 C +ATOM 30176 C THR P 222 1.115 34.631 26.483 1.00101.85 C +ATOM 30177 O THR P 222 0.386 34.090 25.640 1.00 82.55 O +ATOM 30178 CB THR P 222 1.233 37.105 26.789 1.00 91.06 C +ATOM 30179 OG1 THR P 222 0.547 38.240 27.351 1.00112.22 O +ATOM 30180 CG2 THR P 222 1.219 37.161 25.249 1.00 91.40 C +ATOM 30181 N GLY P 223 2.389 34.285 26.689 1.00 92.83 N +ATOM 30182 CA GLY P 223 3.006 33.151 26.002 1.00 91.91 C +ATOM 30183 C GLY P 223 2.236 31.861 26.231 1.00 95.53 C +ATOM 30184 O GLY P 223 2.074 31.048 25.313 1.00111.00 O +ATOM 30185 N VAL P 224 1.758 31.658 27.457 1.00 92.53 N +ATOM 30186 CA VAL P 224 1.034 30.435 27.784 1.00105.61 C +ATOM 30187 C VAL P 224 -0.256 30.388 26.978 1.00110.53 C +ATOM 30188 O VAL P 224 -0.639 29.336 26.467 1.00112.67 O +ATOM 30189 CB VAL P 224 0.718 30.334 29.293 1.00128.91 C +ATOM 30190 CG1 VAL P 224 -0.210 29.152 29.563 1.00124.27 C +ATOM 30191 CG2 VAL P 224 2.008 30.208 30.108 1.00124.02 C +ATOM 30192 N ILE P 225 -0.935 31.530 26.878 1.00116.78 N +ATOM 30193 CA ILE P 225 -2.175 31.597 26.108 1.00128.19 C +ATOM 30194 C ILE P 225 -1.912 31.246 24.641 1.00135.49 C +ATOM 30195 O ILE P 225 -2.575 30.356 24.112 1.00125.10 O +ATOM 30196 CB ILE P 225 -2.845 32.974 26.198 1.00128.17 C +ATOM 30197 CG1 ILE P 225 -3.372 33.220 27.614 1.00129.26 C +ATOM 30198 CG2 ILE P 225 -4.004 33.061 25.216 1.00127.10 C +ATOM 30199 CD1 ILE P 225 -3.659 34.680 27.913 1.00147.02 C +ATOM 30200 N PHE P 226 -0.925 31.904 24.018 1.00128.17 N +ATOM 30201 CA PHE P 226 -0.543 31.614 22.623 1.00116.99 C +ATOM 30202 C PHE P 226 -0.177 30.146 22.424 1.00120.53 C +ATOM 30203 O PHE P 226 -0.465 29.566 21.379 1.00125.71 O +ATOM 30204 CB PHE P 226 0.636 32.474 22.161 1.00120.37 C +ATOM 30205 CG PHE P 226 0.255 33.893 21.766 1.00146.16 C +ATOM 30206 CD1 PHE P 226 -0.640 34.131 20.729 1.00149.60 C +ATOM 30207 CD2 PHE P 226 0.864 34.997 22.383 1.00138.79 C +ATOM 30208 CE1 PHE P 226 -0.953 35.430 20.347 1.00145.49 C +ATOM 30209 CE2 PHE P 226 0.595 36.299 21.976 1.00 96.51 C +ATOM 30210 CZ PHE P 226 -0.352 36.515 20.991 1.00145.19 C +ATOM 30211 N LEU P 227 0.388 29.518 23.454 1.00124.02 N +ATOM 30212 CA LEU P 227 0.677 28.069 23.403 1.00118.78 C +ATOM 30213 C LEU P 227 -0.590 27.260 23.349 1.00 97.96 C +ATOM 30214 O LEU P 227 -0.660 26.293 22.598 1.00 95.62 O +ATOM 30215 CB LEU P 227 1.459 27.568 24.630 1.00121.31 C +ATOM 30216 CG LEU P 227 2.880 27.028 24.424 1.00105.61 C +ATOM 30217 CD1 LEU P 227 3.476 27.729 23.243 1.00 84.87 C +ATOM 30218 CD2 LEU P 227 3.862 27.075 25.600 1.00 86.81 C +ATOM 30219 N ILE P 228 -1.540 27.591 24.224 1.00 79.96 N +ATOM 30220 CA ILE P 228 -2.767 26.808 24.337 1.00 86.18 C +ATOM 30221 C ILE P 228 -3.539 26.945 23.034 1.00 90.46 C +ATOM 30222 O ILE P 228 -3.992 25.949 22.467 1.00 72.56 O +ATOM 30223 CB ILE P 228 -3.664 27.258 25.507 1.00 86.27 C +ATOM 30224 CG1 ILE P 228 -2.980 27.006 26.850 1.00107.69 C +ATOM 30225 CG2 ILE P 228 -4.969 26.494 25.487 1.00 71.10 C +ATOM 30226 CD1 ILE P 228 -3.606 27.745 28.018 1.00114.42 C +ATOM 30227 N ASN P 229 -3.665 28.179 22.554 1.00103.81 N +ATOM 30228 CA ASN P 229 -4.391 28.457 21.313 1.00109.83 C +ATOM 30229 C ASN P 229 -3.750 27.763 20.113 1.00104.03 C +ATOM 30230 O ASN P 229 -4.442 27.095 19.341 1.00130.85 O +ATOM 30231 CB ASN P 229 -4.433 29.958 21.060 1.00131.82 C +ATOM 30232 CG ASN P 229 -5.474 30.346 20.036 1.00157.42 C +ATOM 30233 OD1 ASN P 229 -6.467 29.641 19.835 1.00167.80 O +ATOM 30234 ND2 ASN P 229 -5.279 31.503 19.417 1.00193.07 N +ATOM 30235 N ASP P 230 -2.423 27.842 20.029 1.00 90.34 N +ATOM 30236 CA ASP P 230 -1.665 27.118 19.025 1.00 80.87 C +ATOM 30237 C ASP P 230 -1.907 25.595 19.111 1.00102.86 C +ATOM 30238 O ASP P 230 -2.072 24.923 18.088 1.00106.99 O +ATOM 30239 CB ASP P 230 -0.171 27.401 19.176 1.00 79.80 C +ATOM 30240 CG ASP P 230 0.657 26.816 18.036 1.00 86.66 C +ATOM 30241 OD1 ASP P 230 0.580 27.368 16.945 1.00 90.00 O +ATOM 30242 OD2 ASP P 230 1.394 25.829 18.248 1.00111.28 O +ATOM 30243 N GLY P 231 -1.935 25.049 20.327 1.00109.83 N +ATOM 30244 CA GLY P 231 -2.152 23.615 20.520 1.00106.01 C +ATOM 30245 C GLY P 231 -3.562 23.187 20.147 1.00121.81 C +ATOM 30246 O GLY P 231 -3.772 22.085 19.613 1.00169.86 O +ATOM 30247 N ILE P 232 -4.530 24.071 20.395 1.00129.22 N +ATOM 30248 CA ILE P 232 -5.921 23.846 19.962 1.00134.62 C +ATOM 30249 C ILE P 232 -6.014 23.729 18.440 1.00124.64 C +ATOM 30250 O ILE P 232 -6.557 22.756 17.929 1.00123.83 O +ATOM 30251 CB ILE P 232 -6.862 24.976 20.444 1.00142.99 C +ATOM 30252 CG1 ILE P 232 -7.080 24.854 21.955 1.00157.46 C +ATOM 30253 CG2 ILE P 232 -8.199 24.942 19.705 1.00134.62 C +ATOM 30254 CD1 ILE P 232 -7.617 26.113 22.600 1.00178.05 C +ATOM 30255 N ASP P 233 -5.443 24.704 17.736 1.00116.74 N +ATOM 30256 CA ASP P 233 -5.364 24.675 16.276 1.00112.09 C +ATOM 30257 C ASP P 233 -4.710 23.386 15.771 1.00126.13 C +ATOM 30258 O ASP P 233 -5.234 22.734 14.876 1.00147.15 O +ATOM 30259 CB ASP P 233 -4.581 25.889 15.745 1.00116.67 C +ATOM 30260 CG ASP P 233 -5.278 27.221 16.030 1.00109.37 C +ATOM 30261 OD1 ASP P 233 -6.250 27.241 16.816 1.00121.11 O +ATOM 30262 OD2 ASP P 233 -4.803 28.260 15.517 1.00 97.97 O +ATOM 30263 N ARG P 234 -3.553 23.033 16.329 1.00162.96 N +ATOM 30264 CA ARG P 234 -2.748 21.916 15.812 1.00187.40 C +ATOM 30265 C ARG P 234 -3.209 20.542 16.295 1.00158.38 C +ATOM 30266 O ARG P 234 -2.639 19.521 15.902 1.00136.46 O +ATOM 30267 CB ARG P 234 -1.273 22.123 16.163 1.00215.18 C +ATOM 30268 CG ARG P 234 -0.636 23.223 15.333 1.00218.61 C +ATOM 30269 CD ARG P 234 0.610 23.811 15.984 1.00193.24 C +ATOM 30270 NE ARG P 234 1.101 24.937 15.192 1.00152.30 N +ATOM 30271 CZ ARG P 234 2.307 25.004 14.649 1.00141.00 C +ATOM 30272 NH1 ARG P 234 3.200 24.048 14.914 1.00158.65 N +ATOM 30273 NH2 ARG P 234 2.614 25.992 13.808 1.00 98.24 N +ATOM 30274 N GLY P 235 -4.255 20.513 17.118 1.00140.91 N +ATOM 30275 CA GLY P 235 -4.846 19.256 17.564 1.00125.87 C +ATOM 30276 C GLY P 235 -4.019 18.549 18.623 1.00105.49 C +ATOM 30277 O GLY P 235 -3.995 17.319 18.674 1.00101.56 O +ATOM 30278 N LEU P 236 -3.327 19.313 19.461 1.00108.61 N +ATOM 30279 CA LEU P 236 -2.701 18.730 20.654 1.00125.01 C +ATOM 30280 C LEU P 236 -3.790 18.407 21.672 1.00124.81 C +ATOM 30281 O LEU P 236 -3.825 17.315 22.233 1.00129.07 O +ATOM 30282 CB LEU P 236 -1.663 19.680 21.281 1.00147.64 C +ATOM 30283 CG LEU P 236 -0.245 19.691 20.690 1.00164.40 C +ATOM 30284 CD1 LEU P 236 -0.198 20.503 19.400 1.00154.47 C +ATOM 30285 CD2 LEU P 236 0.750 20.255 21.696 1.00173.00 C +ATOM 30286 N TRP P 237 -4.670 19.373 21.913 1.00138.24 N +ATOM 30287 CA TRP P 237 -5.736 19.223 22.905 1.00146.35 C +ATOM 30288 C TRP P 237 -7.042 19.836 22.384 1.00151.42 C +ATOM 30289 O TRP P 237 -7.027 20.587 21.400 1.00110.92 O +ATOM 30290 CB TRP P 237 -5.316 19.862 24.233 1.00137.02 C +ATOM 30291 CG TRP P 237 -4.437 21.060 24.050 1.00134.85 C +ATOM 30292 CD1 TRP P 237 -4.796 22.251 23.500 1.00148.74 C +ATOM 30293 CD2 TRP P 237 -3.054 21.184 24.409 1.00128.75 C +ATOM 30294 NE1 TRP P 237 -3.727 23.114 23.498 1.00145.85 N +ATOM 30295 CE2 TRP P 237 -2.645 22.488 24.054 1.00129.20 C +ATOM 30296 CE3 TRP P 237 -2.136 20.338 25.025 1.00133.29 C +ATOM 30297 CZ2 TRP P 237 -1.347 22.952 24.254 1.00116.47 C +ATOM 30298 CZ3 TRP P 237 -0.848 20.807 25.238 1.00151.07 C +ATOM 30299 CH2 TRP P 237 -0.470 22.112 24.857 1.00132.40 C +ATOM 30300 N ASP P 238 -8.155 19.499 23.039 1.00151.92 N +ATOM 30301 CA ASP P 238 -9.485 19.878 22.559 1.00162.67 C +ATOM 30302 C ASP P 238 -10.355 20.552 23.628 1.00167.81 C +ATOM 30303 O ASP P 238 -10.263 20.236 24.818 1.00125.61 O +ATOM 30304 CB ASP P 238 -10.232 18.661 22.011 1.00150.95 C +ATOM 30305 CG ASP P 238 -9.469 17.952 20.917 1.00149.20 C +ATOM 30306 OD1 ASP P 238 -8.549 17.186 21.253 1.00169.19 O +ATOM 30307 OD2 ASP P 238 -9.775 18.161 19.723 1.00165.48 O +ATOM 30308 N LEU P 239 -11.225 21.460 23.175 1.00154.09 N +ATOM 30309 CA LEU P 239 -12.106 22.215 24.060 1.00117.84 C +ATOM 30310 C LEU P 239 -13.264 21.348 24.500 1.00118.35 C +ATOM 30311 O LEU P 239 -13.757 20.514 23.737 1.00120.31 O +ATOM 30312 CB LEU P 239 -12.644 23.467 23.358 1.00104.08 C +ATOM 30313 CG LEU P 239 -11.742 24.691 23.197 1.00127.95 C +ATOM 30314 CD1 LEU P 239 -12.508 25.851 22.580 1.00140.97 C +ATOM 30315 CD2 LEU P 239 -11.162 25.111 24.533 1.00147.82 C +ATOM 30316 N GLN P 240 -13.693 21.550 25.740 1.00130.61 N +ATOM 30317 CA GLN P 240 -14.931 20.946 26.234 1.00135.09 C +ATOM 30318 C GLN P 240 -16.103 21.295 25.316 1.00145.76 C +ATOM 30319 O GLN P 240 -16.772 20.408 24.777 1.00180.04 O +ATOM 30320 CB GLN P 240 -15.226 21.427 27.661 1.00133.38 C +ATOM 30321 CG GLN P 240 -16.386 20.701 28.333 1.00128.40 C +ATOM 30322 CD GLN P 240 -16.089 19.231 28.565 1.00126.13 C +ATOM 30323 OE1 GLN P 240 -15.394 18.872 29.519 1.00153.18 O +ATOM 30324 NE2 GLN P 240 -16.572 18.376 27.666 1.00127.61 N +ATOM 30325 N ASN P 241 -16.312 22.592 25.120 1.00145.87 N +ATOM 30326 CA ASN P 241 -17.367 23.101 24.251 1.00161.19 C +ATOM 30327 C ASN P 241 -16.800 23.613 22.939 1.00172.51 C +ATOM 30328 O ASN P 241 -16.116 24.651 22.908 1.00213.54 O +ATOM 30329 CB ASN P 241 -18.096 24.246 24.944 1.00173.55 C +ATOM 30330 CG ASN P 241 -19.406 23.815 25.546 1.00183.81 C +ATOM 30331 OD1 ASN P 241 -20.460 24.070 24.972 1.00199.16 O +ATOM 30332 ND2 ASN P 241 -19.353 23.141 26.695 1.00179.67 N +ATOM 30333 N LYS P 242 -17.092 22.897 21.857 1.00152.67 N +ATOM 30334 CA LYS P 242 -16.581 23.271 20.541 1.00147.28 C +ATOM 30335 C LYS P 242 -17.202 24.595 20.128 1.00161.40 C +ATOM 30336 O LYS P 242 -16.610 25.365 19.354 1.00129.81 O +ATOM 30337 CB LYS P 242 -16.879 22.175 19.519 1.00152.71 C +ATOM 30338 CG LYS P 242 -16.467 20.777 19.977 1.00154.25 C +ATOM 30339 CD LYS P 242 -15.556 20.089 18.973 1.00167.96 C +ATOM 30340 CE LYS P 242 -14.356 19.454 19.661 1.00166.05 C +ATOM 30341 NZ LYS P 242 -13.524 18.642 18.731 1.00165.70 N +ATOM 30342 N ALA P 243 -18.380 24.864 20.702 1.00185.31 N +ATOM 30343 CA ALA P 243 -19.088 26.135 20.542 1.00208.14 C +ATOM 30344 C ALA P 243 -18.286 27.304 21.108 1.00219.74 C +ATOM 30345 O ALA P 243 -18.549 28.461 20.758 1.00277.24 O +ATOM 30346 CB ALA P 243 -20.453 26.068 21.221 1.00180.38 C +ATOM 30347 N GLU P 244 -17.321 27.012 21.983 1.00180.09 N +ATOM 30348 CA GLU P 244 -16.538 28.072 22.611 1.00151.26 C +ATOM 30349 C GLU P 244 -15.260 28.372 21.849 1.00132.17 C +ATOM 30350 O GLU P 244 -14.408 29.094 22.348 1.00122.79 O +ATOM 30351 CB GLU P 244 -16.207 27.719 24.059 1.00152.66 C +ATOM 30352 CG GLU P 244 -17.396 27.814 25.002 1.00161.66 C +ATOM 30353 CD GLU P 244 -16.995 27.714 26.461 1.00168.43 C +ATOM 30354 OE1 GLU P 244 -16.705 26.591 26.931 1.00168.94 O +ATOM 30355 OE2 GLU P 244 -16.961 28.760 27.141 1.00174.52 O +ATOM 30356 N ARG P 245 -15.126 27.837 20.640 1.00122.08 N +ATOM 30357 CA ARG P 245 -14.002 28.200 19.785 1.00144.81 C +ATOM 30358 C ARG P 245 -13.880 29.706 19.514 1.00137.41 C +ATOM 30359 O ARG P 245 -12.768 30.227 19.412 1.00123.86 O +ATOM 30360 CB ARG P 245 -14.068 27.487 18.452 1.00159.66 C +ATOM 30361 CG ARG P 245 -12.790 27.699 17.651 1.00156.21 C +ATOM 30362 CD ARG P 245 -12.726 26.918 16.421 1.00153.91 C +ATOM 30363 NE ARG P 245 -11.733 27.501 15.535 1.00149.12 N +ATOM 30364 CZ ARG P 245 -10.415 27.350 15.636 1.00136.61 C +ATOM 30365 NH1 ARG P 245 -9.871 26.622 16.591 1.00121.11 N +ATOM 30366 NH2 ARG P 245 -9.620 27.950 14.750 1.00155.64 N +ATOM 30367 N GLN P 246 -15.015 30.386 19.362 1.00153.18 N +ATOM 30368 CA GLN P 246 -15.007 31.813 19.036 1.00154.16 C +ATOM 30369 C GLN P 246 -15.059 32.672 20.298 1.00163.56 C +ATOM 30370 O GLN P 246 -15.455 33.833 20.250 1.00204.57 O +ATOM 30371 CB GLN P 246 -16.169 32.174 18.102 1.00147.98 C +ATOM 30372 CG GLN P 246 -16.021 31.653 16.689 1.00139.90 C +ATOM 30373 CD GLN P 246 -16.306 30.170 16.597 1.00164.25 C +ATOM 30374 OE1 GLN P 246 -17.291 29.677 17.152 1.00140.96 O +ATOM 30375 NE2 GLN P 246 -15.465 29.453 15.858 1.00208.75 N +ATOM 30376 N ASN P 247 -14.659 32.090 21.424 1.00153.44 N +ATOM 30377 CA ASN P 247 -14.409 32.838 22.658 1.00143.66 C +ATOM 30378 C ASN P 247 -13.667 34.149 22.404 1.00148.98 C +ATOM 30379 O ASN P 247 -12.732 34.187 21.595 1.00168.36 O +ATOM 30380 CB ASN P 247 -13.568 31.984 23.600 1.00150.36 C +ATOM 30381 CG ASN P 247 -13.766 32.359 25.044 1.00143.46 C +ATOM 30382 OD1 ASN P 247 -12.865 32.903 25.688 1.00116.73 O +ATOM 30383 ND2 ASN P 247 -14.929 32.009 25.581 1.00149.66 N +ATOM 30384 N ASP P 248 -14.083 35.214 23.088 1.00164.76 N +ATOM 30385 CA ASP P 248 -13.506 36.558 22.877 1.00195.01 C +ATOM 30386 C ASP P 248 -11.981 36.536 22.997 1.00190.89 C +ATOM 30387 O ASP P 248 -11.258 37.120 22.179 1.00164.46 O +ATOM 30388 CB ASP P 248 -14.064 37.556 23.907 1.00203.17 C +ATOM 30389 CG ASP P 248 -15.516 37.922 23.656 1.00208.17 C +ATOM 30390 OD1 ASP P 248 -15.913 38.068 22.482 1.00219.29 O +ATOM 30391 OD2 ASP P 248 -16.259 38.083 24.644 1.00206.71 O +ATOM 30392 N ILE P 249 -11.506 35.874 24.047 1.00184.27 N +ATOM 30393 CA ILE P 249 -10.087 35.831 24.359 1.00158.93 C +ATOM 30394 C ILE P 249 -9.341 35.048 23.277 1.00162.57 C +ATOM 30395 O ILE P 249 -8.346 35.517 22.718 1.00164.04 O +ATOM 30396 CB ILE P 249 -9.861 35.186 25.740 1.00145.12 C +ATOM 30397 CG1 ILE P 249 -10.513 36.035 26.842 1.00144.33 C +ATOM 30398 CG2 ILE P 249 -8.376 35.049 26.019 1.00162.14 C +ATOM 30399 CD1 ILE P 249 -10.774 35.289 28.136 1.00138.34 C +ATOM 30400 N LEU P 250 -9.860 33.867 22.953 1.00162.93 N +ATOM 30401 CA LEU P 250 -9.226 32.987 21.962 1.00147.50 C +ATOM 30402 C LEU P 250 -9.116 33.629 20.584 1.00143.70 C +ATOM 30403 O LEU P 250 -8.116 33.442 19.894 1.00120.21 O +ATOM 30404 CB LEU P 250 -9.988 31.663 21.855 1.00142.34 C +ATOM 30405 CG LEU P 250 -9.687 30.641 22.960 1.00132.40 C +ATOM 30406 CD1 LEU P 250 -10.682 29.489 22.958 1.00112.55 C +ATOM 30407 CD2 LEU P 250 -8.273 30.115 22.807 1.00135.28 C +ATOM 30408 N VAL P 251 -10.144 34.382 20.191 1.00161.08 N +ATOM 30409 CA VAL P 251 -10.126 35.074 18.901 1.00179.36 C +ATOM 30410 C VAL P 251 -9.242 36.321 18.941 1.00174.81 C +ATOM 30411 O VAL P 251 -8.733 36.766 17.909 1.00195.16 O +ATOM 30412 CB VAL P 251 -11.544 35.459 18.415 1.00177.02 C +ATOM 30413 CG1 VAL P 251 -12.442 34.226 18.367 1.00169.49 C +ATOM 30414 CG2 VAL P 251 -12.150 36.561 19.278 1.00165.71 C +ATOM 30415 N LYS P 252 -9.074 36.888 20.130 1.00152.76 N +ATOM 30416 CA LYS P 252 -8.179 38.022 20.309 1.00158.00 C +ATOM 30417 C LYS P 252 -6.721 37.597 20.062 1.00172.93 C +ATOM 30418 O LYS P 252 -5.974 38.267 19.330 1.00154.05 O +ATOM 30419 CB LYS P 252 -8.372 38.595 21.716 1.00148.38 C +ATOM 30420 CG LYS P 252 -7.484 39.777 22.068 1.00151.61 C +ATOM 30421 CD LYS P 252 -7.759 40.230 23.496 1.00174.98 C +ATOM 30422 CE LYS P 252 -6.472 40.433 24.282 1.00206.39 C +ATOM 30423 NZ LYS P 252 -6.712 40.615 25.742 1.00199.23 N +ATOM 30424 N TYR P 253 -6.329 36.469 20.654 1.00180.35 N +ATOM 30425 CA TYR P 253 -4.956 35.960 20.521 1.00165.60 C +ATOM 30426 C TYR P 253 -4.747 35.303 19.169 1.00172.17 C +ATOM 30427 O TYR P 253 -3.641 35.338 18.612 1.00157.76 O +ATOM 30428 CB TYR P 253 -4.618 34.990 21.659 1.00140.02 C +ATOM 30429 CG TYR P 253 -4.441 35.726 22.979 1.00161.36 C +ATOM 30430 CD1 TYR P 253 -3.228 36.333 23.306 1.00157.59 C +ATOM 30431 CD2 TYR P 253 -5.510 35.893 23.858 1.00173.52 C +ATOM 30432 CE1 TYR P 253 -3.081 37.047 24.485 1.00135.74 C +ATOM 30433 CE2 TYR P 253 -5.362 36.593 25.051 1.00145.75 C +ATOM 30434 CZ TYR P 253 -4.146 37.167 25.357 1.00126.81 C +ATOM 30435 OH TYR P 253 -3.978 37.829 26.546 1.00 99.68 O +ATOM 30436 N ARG P 254 -5.817 34.715 18.640 1.00171.00 N +ATOM 30437 CA ARG P 254 -5.820 34.224 17.264 1.00171.34 C +ATOM 30438 C ARG P 254 -5.526 35.378 16.304 1.00160.97 C +ATOM 30439 O ARG P 254 -4.787 35.208 15.326 1.00153.15 O +ATOM 30440 CB ARG P 254 -7.175 33.587 16.915 1.00177.42 C +ATOM 30441 CG ARG P 254 -7.215 32.958 15.531 1.00165.44 C +ATOM 30442 CD ARG P 254 -8.374 31.996 15.354 1.00170.36 C +ATOM 30443 NE ARG P 254 -8.286 30.810 16.207 1.00181.04 N +ATOM 30444 CZ ARG P 254 -9.063 30.555 17.261 1.00173.72 C +ATOM 30445 NH1 ARG P 254 -9.990 31.421 17.648 1.00161.18 N +ATOM 30446 NH2 ARG P 254 -8.937 29.398 17.912 1.00170.59 N +ATOM 30447 N HIS P 255 -6.102 36.545 16.600 1.00161.35 N +ATOM 30448 CA HIS P 255 -5.925 37.741 15.772 1.00173.91 C +ATOM 30449 C HIS P 255 -4.516 38.314 15.846 1.00160.49 C +ATOM 30450 O HIS P 255 -3.990 38.810 14.851 1.00167.87 O +ATOM 30451 CB HIS P 255 -6.943 38.825 16.148 1.00178.66 C +ATOM 30452 CG HIS P 255 -8.045 38.990 15.147 1.00178.47 C +ATOM 30453 ND1 HIS P 255 -9.090 38.098 15.034 1.00156.62 N +ATOM 30454 CD2 HIS P 255 -8.253 39.937 14.201 1.00168.92 C +ATOM 30455 CE1 HIS P 255 -9.896 38.490 14.063 1.00165.95 C +ATOM 30456 NE2 HIS P 255 -9.413 39.605 13.544 1.00178.87 N +ATOM 30457 N MET P 256 -3.885 38.216 17.009 1.00159.72 N +ATOM 30458 CA MET P 256 -2.508 38.695 17.141 1.00158.31 C +ATOM 30459 C MET P 256 -1.513 37.851 16.308 1.00170.33 C +ATOM 30460 O MET P 256 -0.443 38.349 15.930 1.00111.01 O +ATOM 30461 CB MET P 256 -2.103 38.753 18.621 1.00169.48 C +ATOM 30462 CG MET P 256 -3.081 39.536 19.493 1.00167.37 C +ATOM 30463 SD MET P 256 -2.437 40.090 21.086 1.00170.23 S +ATOM 30464 CE MET P 256 -1.274 41.343 20.534 1.00142.51 C +ATOM 30465 N SER P 257 -1.883 36.596 16.016 1.00186.64 N +ATOM 30466 CA SER P 257 -1.092 35.707 15.154 1.00170.20 C +ATOM 30467 C SER P 257 -1.276 36.063 13.686 1.00149.13 C +ATOM 30468 O SER P 257 -0.525 36.889 13.156 1.00166.11 O +ATOM 30469 CB SER P 257 -1.494 34.246 15.370 1.00155.31 C +ATOM 30470 OG SER P 257 -1.654 33.961 16.752 1.00125.99 O +TER 30471 SER P 257 +ATOM 30472 N LEU Q 2 -1.730 54.819 47.273 1.00137.10 N +ATOM 30473 CA LEU Q 2 -0.714 54.807 46.174 1.00131.46 C +ATOM 30474 C LEU Q 2 0.713 54.748 46.767 1.00142.54 C +ATOM 30475 O LEU Q 2 1.503 55.722 46.704 1.00 94.72 O +ATOM 30476 CB LEU Q 2 -0.889 56.013 45.245 1.00129.29 C +ATOM 30477 CG LEU Q 2 -2.215 56.165 44.468 1.00124.98 C +ATOM 30478 CD1 LEU Q 2 -2.171 57.449 43.636 1.00122.40 C +ATOM 30479 CD2 LEU Q 2 -2.574 54.971 43.579 1.00111.77 C +ATOM 30480 N THR Q 3 0.966 53.622 47.441 1.00165.17 N +ATOM 30481 CA THR Q 3 2.308 53.146 47.800 1.00175.49 C +ATOM 30482 C THR Q 3 2.400 51.608 47.641 1.00192.22 C +ATOM 30483 O THR Q 3 3.451 50.997 47.876 1.00166.34 O +ATOM 30484 CB THR Q 3 2.683 53.504 49.252 1.00157.12 C +ATOM 30485 OG1 THR Q 3 1.858 52.754 50.168 1.00138.36 O +ATOM 30486 CG2 THR Q 3 2.555 55.012 49.501 1.00145.65 C +ATOM 30487 N ALA Q 4 1.275 50.982 47.309 1.00180.40 N +ATOM 30488 CA ALA Q 4 1.289 49.649 46.714 1.00149.95 C +ATOM 30489 C ALA Q 4 1.771 49.785 45.254 1.00151.77 C +ATOM 30490 O ALA Q 4 2.173 50.868 44.824 1.00135.92 O +ATOM 30491 CB ALA Q 4 -0.098 49.019 46.812 1.00139.95 C +ATOM 30492 N PRO Q 5 1.790 48.688 44.487 1.00164.04 N +ATOM 30493 CA PRO Q 5 2.537 48.881 43.250 1.00144.60 C +ATOM 30494 C PRO Q 5 1.763 49.658 42.178 1.00113.93 C +ATOM 30495 O PRO Q 5 0.551 49.856 42.294 1.00131.15 O +ATOM 30496 CB PRO Q 5 2.832 47.441 42.807 1.00165.97 C +ATOM 30497 CG PRO Q 5 1.715 46.613 43.383 1.00188.95 C +ATOM 30498 CD PRO Q 5 1.103 47.378 44.529 1.00180.71 C +ATOM 30499 N PRO Q 6 2.451 50.064 41.113 1.00 95.59 N +ATOM 30500 CA PRO Q 6 1.787 50.514 39.875 1.00115.97 C +ATOM 30501 C PRO Q 6 1.232 49.377 39.003 1.00112.68 C +ATOM 30502 O PRO Q 6 1.769 48.277 39.023 1.00 62.58 O +ATOM 30503 CB PRO Q 6 2.886 51.291 39.131 1.00106.65 C +ATOM 30504 CG PRO Q 6 4.168 50.858 39.736 1.00 95.13 C +ATOM 30505 CD PRO Q 6 3.907 50.221 41.074 1.00 90.40 C +ATOM 30506 N LYS Q 7 0.206 49.673 38.197 1.00129.80 N +ATOM 30507 CA LYS Q 7 -0.398 48.665 37.320 1.00140.10 C +ATOM 30508 C LYS Q 7 0.137 48.736 35.890 1.00136.61 C +ATOM 30509 O LYS Q 7 0.846 49.674 35.519 1.00 93.14 O +ATOM 30510 CB LYS Q 7 -1.922 48.782 37.302 1.00143.19 C +ATOM 30511 CG LYS Q 7 -2.591 48.411 38.606 1.00166.52 C +ATOM 30512 CD LYS Q 7 -3.067 49.624 39.403 1.00163.00 C +ATOM 30513 CE LYS Q 7 -3.998 49.195 40.525 1.00158.68 C +ATOM 30514 NZ LYS Q 7 -3.940 50.127 41.681 1.00154.72 N +ATOM 30515 N GLU Q 8 -0.169 47.699 35.113 1.00160.66 N +ATOM 30516 CA GLU Q 8 0.542 47.418 33.863 1.00194.03 C +ATOM 30517 C GLU Q 8 0.322 48.475 32.778 1.00153.86 C +ATOM 30518 O GLU Q 8 -0.791 48.714 32.329 1.00130.03 O +ATOM 30519 CB GLU Q 8 0.227 46.017 33.341 1.00231.64 C +ATOM 30520 CG GLU Q 8 1.439 45.053 33.484 1.00229.68 C +ATOM 30521 CD GLU Q 8 1.232 43.907 34.478 1.00218.24 C +ATOM 30522 OE1 GLU Q 8 0.716 44.209 35.590 1.00248.70 O +ATOM 30523 OE2 GLU Q 8 1.648 42.734 34.178 1.00107.37 O +ATOM 30524 N ALA Q 9 1.413 49.122 32.387 1.00148.17 N +ATOM 30525 CA ALA Q 9 1.432 50.040 31.257 1.00134.87 C +ATOM 30526 C ALA Q 9 1.939 49.328 29.999 1.00141.22 C +ATOM 30527 O ALA Q 9 3.105 48.930 29.934 1.00192.38 O +ATOM 30528 CB ALA Q 9 2.328 51.225 31.587 1.00126.17 C +ATOM 30529 N ALA Q 10 1.062 49.190 29.005 1.00133.00 N +ATOM 30530 CA ALA Q 10 1.345 48.496 27.724 1.00142.81 C +ATOM 30531 C ALA Q 10 1.093 47.004 27.827 1.00152.08 C +ATOM 30532 O ALA Q 10 1.060 46.461 28.944 1.00129.51 O +ATOM 30533 CB ALA Q 10 2.759 48.771 27.209 1.00114.62 C +ATOM 30534 N ARG Q 11 0.892 46.371 26.661 1.00145.39 N +ATOM 30535 CA ARG Q 11 0.482 44.975 26.587 1.00141.56 C +ATOM 30536 C ARG Q 11 1.618 44.095 26.094 1.00132.69 C +ATOM 30537 O ARG Q 11 2.455 44.519 25.291 1.00150.36 O +ATOM 30538 CB ARG Q 11 -0.717 44.803 25.636 1.00156.03 C +ATOM 30539 CG ARG Q 11 -0.399 45.037 24.168 1.00163.73 C +ATOM 30540 CD ARG Q 11 -1.622 45.497 23.384 1.00172.20 C +ATOM 30541 NE ARG Q 11 -1.431 46.838 22.838 1.00190.19 N +ATOM 30542 CZ ARG Q 11 -2.303 47.443 22.038 1.00207.28 C +ATOM 30543 NH1 ARG Q 11 -3.442 46.843 21.722 1.00230.22 N +ATOM 30544 NH2 ARG Q 11 -2.050 48.659 21.567 1.00211.84 N +ATOM 30545 N PRO Q 12 1.632 42.831 26.527 1.00132.15 N +ATOM 30546 CA PRO Q 12 2.518 41.896 25.861 1.00137.00 C +ATOM 30547 C PRO Q 12 2.037 41.666 24.434 1.00105.12 C +ATOM 30548 O PRO Q 12 0.937 41.146 24.221 1.00118.61 O +ATOM 30549 CB PRO Q 12 2.391 40.610 26.698 1.00166.93 C +ATOM 30550 CG PRO Q 12 1.703 41.005 27.960 1.00169.21 C +ATOM 30551 CD PRO Q 12 0.851 42.183 27.588 1.00145.72 C +ATOM 30552 N THR Q 13 2.847 42.080 23.472 1.00 77.26 N +ATOM 30553 CA THR Q 13 2.666 41.653 22.105 1.00 90.36 C +ATOM 30554 C THR Q 13 3.502 40.397 21.806 1.00109.08 C +ATOM 30555 O THR Q 13 4.470 40.133 22.512 1.00143.22 O +ATOM 30556 CB THR Q 13 3.079 42.780 21.151 1.00 85.75 C +ATOM 30557 OG1 THR Q 13 2.658 42.429 19.816 1.00168.43 O +ATOM 30558 CG2 THR Q 13 4.604 43.049 21.199 1.00 60.51 C +ATOM 30559 N LEU Q 14 3.155 39.626 20.772 1.00 96.31 N +ATOM 30560 CA LEU Q 14 4.110 38.628 20.308 1.00 87.15 C +ATOM 30561 C LEU Q 14 5.278 39.328 19.559 1.00 95.82 C +ATOM 30562 O LEU Q 14 5.169 40.487 19.221 1.00 93.35 O +ATOM 30563 CB LEU Q 14 3.471 37.509 19.503 1.00 66.06 C +ATOM 30564 CG LEU Q 14 2.682 37.882 18.292 1.00 80.66 C +ATOM 30565 CD1 LEU Q 14 2.822 36.819 17.213 1.00 99.84 C +ATOM 30566 CD2 LEU Q 14 1.244 38.012 18.707 1.00107.66 C +ATOM 30567 N MET Q 15 6.447 38.690 19.495 1.00118.63 N +ATOM 30568 CA MET Q 15 7.718 39.426 19.382 1.00106.20 C +ATOM 30569 C MET Q 15 7.810 40.051 18.003 1.00 82.23 C +ATOM 30570 O MET Q 15 7.751 39.348 16.997 1.00 56.74 O +ATOM 30571 CB MET Q 15 8.946 38.537 19.687 1.00116.31 C +ATOM 30572 CG MET Q 15 10.123 39.326 20.245 1.00102.45 C +ATOM 30573 SD MET Q 15 11.808 38.972 19.729 1.00 94.35 S +ATOM 30574 CE MET Q 15 11.729 37.883 18.326 1.00 82.94 C +ATOM 30575 N PRO Q 16 7.976 41.374 17.965 1.00 84.03 N +ATOM 30576 CA PRO Q 16 7.977 42.161 16.743 1.00103.15 C +ATOM 30577 C PRO Q 16 9.115 41.821 15.751 1.00104.58 C +ATOM 30578 O PRO Q 16 10.085 42.561 15.615 1.00 76.57 O +ATOM 30579 CB PRO Q 16 8.101 43.605 17.256 1.00103.72 C +ATOM 30580 CG PRO Q 16 8.780 43.475 18.558 1.00 98.63 C +ATOM 30581 CD PRO Q 16 8.245 42.207 19.145 1.00 86.15 C +ATOM 30582 N ARG Q 17 8.898 40.775 14.964 1.00107.29 N +ATOM 30583 CA ARG Q 17 9.766 40.453 13.832 1.00 90.82 C +ATOM 30584 C ARG Q 17 9.306 41.213 12.589 1.00 99.17 C +ATOM 30585 O ARG Q 17 8.103 41.399 12.392 1.00109.40 O +ATOM 30586 CB ARG Q 17 9.735 38.932 13.588 1.00 68.04 C +ATOM 30587 CG ARG Q 17 10.730 38.170 14.436 1.00 65.63 C +ATOM 30588 CD ARG Q 17 10.458 36.675 14.523 1.00 60.36 C +ATOM 30589 NE ARG Q 17 9.397 36.389 15.477 1.00 75.50 N +ATOM 30590 CZ ARG Q 17 8.882 35.183 15.679 1.00104.36 C +ATOM 30591 NH1 ARG Q 17 9.374 34.144 15.007 1.00120.02 N +ATOM 30592 NH2 ARG Q 17 7.880 35.014 16.559 1.00121.34 N +ATOM 30593 N ALA Q 18 10.238 41.608 11.728 1.00103.40 N +ATOM 30594 CA ALA Q 18 9.875 42.358 10.517 1.00133.28 C +ATOM 30595 C ALA Q 18 10.084 41.595 9.183 1.00110.18 C +ATOM 30596 O ALA Q 18 9.446 40.570 8.940 1.00 65.93 O +ATOM 30597 CB ALA Q 18 10.600 43.695 10.501 1.00167.22 C +ATOM 30598 N GLN Q 19 10.949 42.119 8.319 1.00110.70 N +ATOM 30599 CA GLN Q 19 10.932 41.745 6.911 1.00128.76 C +ATOM 30600 C GLN Q 19 11.440 40.317 6.700 1.00135.20 C +ATOM 30601 O GLN Q 19 10.822 39.510 5.995 1.00112.62 O +ATOM 30602 CB GLN Q 19 11.797 42.724 6.107 1.00159.10 C +ATOM 30603 CG GLN Q 19 11.747 42.508 4.599 1.00190.83 C +ATOM 30604 CD GLN Q 19 10.332 42.515 4.053 1.00194.74 C +ATOM 30605 OE1 GLN Q 19 9.659 43.549 4.067 1.00216.72 O +ATOM 30606 NE2 GLN Q 19 9.867 41.359 3.578 1.00164.96 N +ATOM 30607 N SER Q 20 12.598 40.035 7.303 1.00152.18 N +ATOM 30608 CA SER Q 20 13.194 38.697 7.329 1.00123.86 C +ATOM 30609 C SER Q 20 12.139 37.622 7.637 1.00111.24 C +ATOM 30610 O SER Q 20 11.998 36.659 6.895 1.00124.79 O +ATOM 30611 CB SER Q 20 14.307 38.660 8.384 1.00113.42 C +ATOM 30612 OG SER Q 20 15.215 39.736 8.217 1.00 83.31 O +ATOM 30613 N TYR Q 21 11.352 37.853 8.686 1.00 97.18 N +ATOM 30614 CA TYR Q 21 10.230 36.985 9.054 1.00 98.19 C +ATOM 30615 C TYR Q 21 9.194 36.785 7.938 1.00115.10 C +ATOM 30616 O TYR Q 21 8.836 35.657 7.607 1.00 96.94 O +ATOM 30617 CB TYR Q 21 9.506 37.564 10.273 1.00110.67 C +ATOM 30618 CG TYR Q 21 8.377 36.706 10.768 1.00130.05 C +ATOM 30619 CD1 TYR Q 21 8.653 35.513 11.458 1.00195.55 C +ATOM 30620 CD2 TYR Q 21 7.049 37.048 10.544 1.00 75.66 C +ATOM 30621 CE1 TYR Q 21 7.645 34.686 11.910 1.00166.33 C +ATOM 30622 CE2 TYR Q 21 6.040 36.230 11.011 1.00 93.03 C +ATOM 30623 CZ TYR Q 21 6.350 35.056 11.709 1.00117.94 C +ATOM 30624 OH TYR Q 21 5.396 34.180 12.153 1.00 95.33 O +ATOM 30625 N LYS Q 22 8.733 37.887 7.355 1.00156.54 N +ATOM 30626 CA LYS Q 22 7.743 37.838 6.279 1.00143.92 C +ATOM 30627 C LYS Q 22 8.216 37.046 5.061 1.00128.03 C +ATOM 30628 O LYS Q 22 7.450 36.284 4.479 1.00100.40 O +ATOM 30629 CB LYS Q 22 7.386 39.256 5.835 1.00163.55 C +ATOM 30630 CG LYS Q 22 6.261 39.869 6.639 1.00154.60 C +ATOM 30631 CD LYS Q 22 4.902 39.382 6.118 1.00116.71 C +ATOM 30632 CE LYS Q 22 4.250 40.468 5.259 1.00131.99 C +ATOM 30633 NZ LYS Q 22 3.907 41.677 6.061 1.00155.97 N +ATOM 30634 N ASP Q 23 9.482 37.241 4.686 1.00126.76 N +ATOM 30635 CA ASP Q 23 10.122 36.429 3.651 1.00120.99 C +ATOM 30636 C ASP Q 23 10.208 34.949 4.041 1.00134.57 C +ATOM 30637 O ASP Q 23 9.860 34.061 3.258 1.00163.15 O +ATOM 30638 CB ASP Q 23 11.536 36.939 3.372 1.00111.32 C +ATOM 30639 CG ASP Q 23 11.534 38.300 2.770 1.00118.33 C +ATOM 30640 OD1 ASP Q 23 10.690 38.530 1.878 1.00156.76 O +ATOM 30641 OD2 ASP Q 23 12.401 39.114 3.131 1.00107.63 O +ATOM 30642 N LEU Q 24 10.633 34.702 5.275 1.00144.73 N +ATOM 30643 CA LEU Q 24 10.859 33.346 5.782 1.00134.70 C +ATOM 30644 C LEU Q 24 9.569 32.510 5.838 1.00138.94 C +ATOM 30645 O LEU Q 24 9.587 31.298 5.604 1.00141.97 O +ATOM 30646 CB LEU Q 24 11.482 33.430 7.186 1.00136.53 C +ATOM 30647 CG LEU Q 24 11.818 32.122 7.902 1.00118.20 C +ATOM 30648 CD1 LEU Q 24 13.200 31.621 7.480 1.00139.15 C +ATOM 30649 CD2 LEU Q 24 11.746 32.309 9.410 1.00 95.47 C +ATOM 30650 N THR Q 25 8.457 33.160 6.183 1.00149.14 N +ATOM 30651 CA THR Q 25 7.168 32.473 6.325 1.00136.19 C +ATOM 30652 C THR Q 25 6.564 32.112 4.970 1.00121.80 C +ATOM 30653 O THR Q 25 6.109 30.993 4.765 1.00 62.11 O +ATOM 30654 CB THR Q 25 6.164 33.334 7.132 1.00178.71 C +ATOM 30655 OG1 THR Q 25 6.182 34.691 6.660 1.00210.01 O +ATOM 30656 CG2 THR Q 25 6.526 33.321 8.609 1.00201.34 C +ATOM 30657 N HIS Q 26 6.558 33.088 4.055 1.00172.87 N +ATOM 30658 CA HIS Q 26 5.944 32.939 2.725 1.00142.37 C +ATOM 30659 C HIS Q 26 6.906 32.263 1.731 1.00 92.38 C +ATOM 30660 O HIS Q 26 6.957 32.615 0.568 1.00 71.03 O +ATOM 30661 CB HIS Q 26 5.467 34.319 2.206 1.00152.26 C +ATOM 30662 CG HIS Q 26 4.372 34.941 3.036 1.00168.70 C +ATOM 30663 ND1 HIS Q 26 4.585 35.440 4.305 1.00192.38 N +ATOM 30664 CD2 HIS Q 26 3.058 35.145 2.775 1.00167.64 C +ATOM 30665 CE1 HIS Q 26 3.449 35.903 4.797 1.00157.76 C +ATOM 30666 NE2 HIS Q 26 2.509 35.748 3.885 1.00146.10 N +ATOM 30667 N LEU Q 27 7.699 31.328 2.216 1.00 80.31 N +ATOM 30668 CA LEU Q 27 8.578 30.574 1.348 1.00 97.94 C +ATOM 30669 C LEU Q 27 7.829 29.346 0.829 1.00104.56 C +ATOM 30670 O LEU Q 27 7.158 28.658 1.597 1.00 82.12 O +ATOM 30671 CB LEU Q 27 9.840 30.126 2.103 1.00130.49 C +ATOM 30672 CG LEU Q 27 11.010 31.112 2.089 1.00142.17 C +ATOM 30673 CD1 LEU Q 27 12.071 30.723 3.112 1.00142.31 C +ATOM 30674 CD2 LEU Q 27 11.624 31.209 0.696 1.00149.04 C +ATOM 30675 N PRO Q 28 7.980 29.039 -0.472 1.00118.27 N +ATOM 30676 CA PRO Q 28 7.292 27.896 -1.102 1.00104.48 C +ATOM 30677 C PRO Q 28 7.702 26.594 -0.469 1.00130.75 C +ATOM 30678 O PRO Q 28 8.894 26.354 -0.302 1.00195.89 O +ATOM 30679 CB PRO Q 28 7.779 27.944 -2.539 1.00103.47 C +ATOM 30680 CG PRO Q 28 9.075 28.709 -2.489 1.00104.07 C +ATOM 30681 CD PRO Q 28 8.897 29.725 -1.404 1.00119.24 C +ATOM 30682 N ALA Q 29 6.736 25.770 -0.082 1.00147.44 N +ATOM 30683 CA ALA Q 29 7.016 24.622 0.793 1.00145.19 C +ATOM 30684 C ALA Q 29 7.736 23.481 0.040 1.00140.48 C +ATOM 30685 O ALA Q 29 7.560 23.316 -1.179 1.00112.52 O +ATOM 30686 CB ALA Q 29 5.733 24.118 1.440 1.00137.83 C +ATOM 30687 N PRO Q 30 8.615 22.741 0.751 1.00126.57 N +ATOM 30688 CA PRO Q 30 9.319 21.575 0.187 1.00109.08 C +ATOM 30689 C PRO Q 30 8.419 20.342 0.093 1.00 93.22 C +ATOM 30690 O PRO Q 30 7.258 20.398 0.532 1.00113.43 O +ATOM 30691 CB PRO Q 30 10.398 21.302 1.220 1.00107.47 C +ATOM 30692 CG PRO Q 30 9.810 21.766 2.511 1.00 92.29 C +ATOM 30693 CD PRO Q 30 8.912 22.923 2.186 1.00107.26 C +ATOM 30694 N THR Q 31 8.940 19.247 -0.467 1.00 76.51 N +ATOM 30695 CA THR Q 31 8.130 18.030 -0.685 1.00 98.69 C +ATOM 30696 C THR Q 31 7.790 17.344 0.630 1.00 99.06 C +ATOM 30697 O THR Q 31 6.780 16.650 0.737 1.00109.99 O +ATOM 30698 CB THR Q 31 8.812 17.005 -1.632 1.00111.21 C +ATOM 30699 OG1 THR Q 31 10.146 16.734 -1.195 1.00121.77 O +ATOM 30700 CG2 THR Q 31 8.843 17.512 -3.074 1.00110.48 C +ATOM 30701 N GLY Q 32 8.634 17.551 1.630 1.00115.90 N +ATOM 30702 CA GLY Q 32 8.305 17.197 3.004 1.00134.59 C +ATOM 30703 C GLY Q 32 9.128 18.085 3.913 1.00140.12 C +ATOM 30704 O GLY Q 32 10.220 18.511 3.523 1.00156.58 O +ATOM 30705 N LYS Q 33 8.660 18.315 5.138 1.00110.34 N +ATOM 30706 CA LYS Q 33 9.512 18.982 6.108 1.00111.60 C +ATOM 30707 C LYS Q 33 10.784 18.155 6.462 1.00145.60 C +ATOM 30708 O LYS Q 33 10.762 16.919 6.451 1.00131.66 O +ATOM 30709 CB LYS Q 33 8.737 19.341 7.366 1.00 75.85 C +ATOM 30710 CG LYS Q 33 8.052 20.667 7.284 1.00 72.66 C +ATOM 30711 CD LYS Q 33 7.151 20.878 8.478 1.00 71.87 C +ATOM 30712 CE LYS Q 33 6.029 21.834 8.143 1.00 83.23 C +ATOM 30713 NZ LYS Q 33 5.038 21.939 9.232 1.00 85.86 N +ATOM 30714 N ILE Q 34 11.880 18.842 6.798 1.00156.20 N +ATOM 30715 CA ILE Q 34 13.140 18.176 7.117 1.00144.01 C +ATOM 30716 C ILE Q 34 13.370 18.241 8.644 1.00143.12 C +ATOM 30717 O ILE Q 34 12.964 19.207 9.308 1.00 80.19 O +ATOM 30718 CB ILE Q 34 14.305 18.776 6.283 1.00137.54 C +ATOM 30719 CG1 ILE Q 34 14.094 18.479 4.801 1.00120.83 C +ATOM 30720 CG2 ILE Q 34 15.658 18.205 6.682 1.00161.53 C +ATOM 30721 CD1 ILE Q 34 13.936 19.725 3.957 1.00135.06 C +ATOM 30722 N PHE Q 35 13.891 17.140 9.191 1.00137.44 N +ATOM 30723 CA PHE Q 35 14.182 17.009 10.608 1.00124.21 C +ATOM 30724 C PHE Q 35 15.523 17.643 10.965 1.00126.96 C +ATOM 30725 O PHE Q 35 16.533 17.287 10.386 1.00125.97 O +ATOM 30726 CB PHE Q 35 14.259 15.536 10.953 1.00101.87 C +ATOM 30727 CG PHE Q 35 12.928 14.910 11.220 1.00 95.11 C +ATOM 30728 CD1 PHE Q 35 11.990 15.530 12.052 1.00 97.45 C +ATOM 30729 CD2 PHE Q 35 12.681 13.632 10.793 1.00108.45 C +ATOM 30730 CE1 PHE Q 35 10.788 14.915 12.361 1.00 84.18 C +ATOM 30731 CE2 PHE Q 35 11.491 12.997 11.125 1.00115.50 C +ATOM 30732 CZ PHE Q 35 10.541 13.642 11.905 1.00 92.73 C +ATOM 30733 N VAL Q 36 15.533 18.565 11.928 1.00113.14 N +ATOM 30734 CA VAL Q 36 16.750 19.330 12.224 1.00 84.88 C +ATOM 30735 C VAL Q 36 17.047 19.429 13.707 1.00 60.62 C +ATOM 30736 O VAL Q 36 16.144 19.362 14.533 1.00 50.31 O +ATOM 30737 CB VAL Q 36 16.665 20.766 11.665 1.00 90.57 C +ATOM 30738 CG1 VAL Q 36 15.753 21.645 12.524 1.00 81.59 C +ATOM 30739 CG2 VAL Q 36 18.052 21.351 11.579 1.00 86.72 C +ATOM 30740 N SER Q 37 18.322 19.553 14.028 1.00 56.93 N +ATOM 30741 CA SER Q 37 18.752 19.574 15.411 1.00 74.20 C +ATOM 30742 C SER Q 37 19.575 20.800 15.616 1.00 70.57 C +ATOM 30743 O SER Q 37 20.486 21.061 14.853 1.00 50.36 O +ATOM 30744 CB SER Q 37 19.632 18.362 15.741 1.00 85.25 C +ATOM 30745 OG SER Q 37 18.876 17.166 15.882 1.00140.91 O +ATOM 30746 N VAL Q 38 19.279 21.560 16.662 1.00111.10 N +ATOM 30747 CA VAL Q 38 20.196 22.639 17.078 1.00115.86 C +ATOM 30748 C VAL Q 38 20.642 22.444 18.522 1.00 90.65 C +ATOM 30749 O VAL Q 38 19.798 22.405 19.421 1.00 95.59 O +ATOM 30750 CB VAL Q 38 19.542 24.032 16.988 1.00143.37 C +ATOM 30751 CG1 VAL Q 38 20.519 25.081 17.462 1.00130.92 C +ATOM 30752 CG2 VAL Q 38 19.079 24.340 15.569 1.00192.80 C +ATOM 30753 N TYR Q 39 21.946 22.265 18.716 1.00 82.54 N +ATOM 30754 CA TYR Q 39 22.512 21.957 20.031 1.00 81.40 C +ATOM 30755 C TYR Q 39 22.864 23.291 20.703 1.00 83.07 C +ATOM 30756 O TYR Q 39 22.437 23.566 21.816 1.00 89.31 O +ATOM 30757 CB TYR Q 39 23.746 20.988 19.908 1.00 67.56 C +ATOM 30758 CG TYR Q 39 23.401 19.477 19.878 1.00 53.20 C +ATOM 30759 CD1 TYR Q 39 22.840 18.892 18.756 1.00 50.83 C +ATOM 30760 CD2 TYR Q 39 23.483 18.692 21.022 1.00 53.17 C +ATOM 30761 CE1 TYR Q 39 22.390 17.563 18.761 1.00 43.62 C +ATOM 30762 CE2 TYR Q 39 23.018 17.381 21.046 1.00 44.70 C +ATOM 30763 CZ TYR Q 39 22.465 16.809 19.902 1.00 40.25 C +ATOM 30764 OH TYR Q 39 22.146 15.459 19.872 1.00 25.24 O +ATOM 30765 N ASN Q 40 23.632 24.137 20.019 1.00 87.55 N +ATOM 30766 CA ASN Q 40 24.051 25.422 20.602 1.00 82.79 C +ATOM 30767 C ASN Q 40 24.671 26.405 19.600 1.00 98.82 C +ATOM 30768 O ASN Q 40 25.552 26.036 18.810 1.00141.75 O +ATOM 30769 CB ASN Q 40 25.062 25.169 21.720 1.00 89.82 C +ATOM 30770 CG ASN Q 40 25.204 26.349 22.663 1.00108.59 C +ATOM 30771 OD1 ASN Q 40 26.254 26.980 22.722 1.00 82.10 O +ATOM 30772 ND2 ASN Q 40 24.120 26.692 23.357 1.00136.88 N +ATOM 30773 N ILE Q 41 24.210 27.656 19.632 1.00 94.67 N +ATOM 30774 CA ILE Q 41 24.875 28.749 18.910 1.00103.32 C +ATOM 30775 C ILE Q 41 25.427 29.793 19.884 1.00 90.44 C +ATOM 30776 O ILE Q 41 24.662 30.381 20.645 1.00115.14 O +ATOM 30777 CB ILE Q 41 23.915 29.442 17.935 1.00 92.50 C +ATOM 30778 CG1 ILE Q 41 23.782 28.635 16.635 1.00100.93 C +ATOM 30779 CG2 ILE Q 41 24.478 30.799 17.541 1.00105.70 C +ATOM 30780 CD1 ILE Q 41 23.009 27.342 16.742 1.00102.61 C +ATOM 30781 N GLN Q 42 26.747 29.969 19.912 1.00 74.36 N +ATOM 30782 CA GLN Q 42 27.395 30.701 21.012 1.00 92.50 C +ATOM 30783 C GLN Q 42 27.519 32.169 20.705 1.00 74.27 C +ATOM 30784 O GLN Q 42 27.562 32.552 19.553 1.00 92.03 O +ATOM 30785 CB GLN Q 42 28.796 30.147 21.323 1.00125.04 C +ATOM 30786 CG GLN Q 42 28.809 28.732 21.882 1.00148.88 C +ATOM 30787 CD GLN Q 42 29.559 27.758 20.984 1.00178.72 C +ATOM 30788 OE1 GLN Q 42 30.784 27.609 21.097 1.00214.04 O +ATOM 30789 NE2 GLN Q 42 28.838 27.117 20.057 1.00147.21 N +ATOM 30790 N ASP Q 43 27.594 32.980 21.758 1.00 69.17 N +ATOM 30791 CA ASP Q 43 27.989 34.375 21.658 1.00 60.20 C +ATOM 30792 C ASP Q 43 29.525 34.514 21.465 1.00 65.95 C +ATOM 30793 O ASP Q 43 30.219 35.028 22.355 1.00 72.96 O +ATOM 30794 CB ASP Q 43 27.543 35.127 22.913 1.00 52.13 C +ATOM 30795 CG ASP Q 43 27.720 36.650 22.781 1.00 63.28 C +ATOM 30796 OD1 ASP Q 43 27.277 37.201 21.764 1.00 56.76 O +ATOM 30797 OD2 ASP Q 43 28.305 37.310 23.682 1.00 73.51 O +ATOM 30798 N GLU Q 44 30.046 34.021 20.337 1.00 57.67 N +ATOM 30799 CA GLU Q 44 31.475 34.015 20.075 1.00 57.13 C +ATOM 30800 C GLU Q 44 32.005 35.430 19.832 1.00 51.06 C +ATOM 30801 O GLU Q 44 33.166 35.614 19.398 1.00 63.06 O +ATOM 30802 CB GLU Q 44 31.813 33.100 18.883 1.00 64.94 C +ATOM 30803 CG GLU Q 44 32.063 31.626 19.234 1.00 91.49 C +ATOM 30804 CD GLU Q 44 32.363 30.720 18.015 1.00126.21 C +ATOM 30805 OE1 GLU Q 44 33.170 31.084 17.117 1.00171.27 O +ATOM 30806 OE2 GLU Q 44 31.823 29.585 17.957 1.00150.73 O +ATOM 30807 N THR Q 45 31.220 36.432 20.216 1.00 53.11 N +ATOM 30808 CA THR Q 45 31.531 37.837 19.886 1.00 80.14 C +ATOM 30809 C THR Q 45 32.666 38.441 20.716 1.00 95.82 C +ATOM 30810 O THR Q 45 33.481 39.200 20.206 1.00 67.59 O +ATOM 30811 CB THR Q 45 30.271 38.733 19.949 1.00 95.40 C +ATOM 30812 OG1 THR Q 45 30.532 39.994 19.331 1.00136.62 O +ATOM 30813 CG2 THR Q 45 29.788 38.994 21.388 1.00 77.45 C +ATOM 30814 N GLY Q 46 32.687 38.145 22.014 1.00116.82 N +ATOM 30815 CA GLY Q 46 33.800 38.576 22.898 1.00 86.51 C +ATOM 30816 C GLY Q 46 33.599 39.957 23.522 1.00 68.71 C +ATOM 30817 O GLY Q 46 34.519 40.613 23.999 1.00 45.91 O +ATOM 30818 N GLN Q 47 32.358 40.381 23.603 1.00 72.13 N +ATOM 30819 CA GLN Q 47 32.142 41.762 23.788 1.00 82.73 C +ATOM 30820 C GLN Q 47 31.109 42.039 24.854 1.00 89.09 C +ATOM 30821 O GLN Q 47 30.082 41.361 24.953 1.00 57.61 O +ATOM 30822 CB GLN Q 47 31.760 42.370 22.473 1.00 78.92 C +ATOM 30823 CG GLN Q 47 32.903 42.367 21.438 1.00 77.33 C +ATOM 30824 CD GLN Q 47 34.192 42.952 21.930 1.00 58.79 C +ATOM 30825 OE1 GLN Q 47 34.272 44.142 22.191 1.00 74.29 O +ATOM 30826 NE2 GLN Q 47 35.160 42.120 22.157 1.00 59.84 N +ATOM 30827 N PHE Q 48 31.449 43.029 25.676 1.00100.09 N +ATOM 30828 CA PHE Q 48 30.600 43.483 26.762 1.00 87.73 C +ATOM 30829 C PHE Q 48 30.349 44.971 26.655 1.00 89.79 C +ATOM 30830 O PHE Q 48 30.992 45.692 25.867 1.00108.13 O +ATOM 30831 CB PHE Q 48 31.267 43.226 28.105 1.00 96.73 C +ATOM 30832 CG PHE Q 48 31.426 41.798 28.421 1.00 77.54 C +ATOM 30833 CD1 PHE Q 48 32.455 41.082 27.805 1.00 67.66 C +ATOM 30834 CD2 PHE Q 48 30.579 41.189 29.345 1.00 45.35 C +ATOM 30835 CE1 PHE Q 48 32.567 39.745 28.018 1.00 64.64 C +ATOM 30836 CE2 PHE Q 48 30.723 39.880 29.616 1.00 44.61 C +ATOM 30837 CZ PHE Q 48 31.699 39.141 28.922 1.00 68.52 C +ATOM 30838 N LYS Q 49 29.395 45.431 27.454 1.00 89.66 N +ATOM 30839 CA LYS Q 49 28.938 46.810 27.373 1.00103.66 C +ATOM 30840 C LYS Q 49 29.910 47.668 28.125 1.00122.09 C +ATOM 30841 O LYS Q 49 30.508 47.220 29.113 1.00173.98 O +ATOM 30842 CB LYS Q 49 27.520 46.968 27.926 1.00 96.83 C +ATOM 30843 CG LYS Q 49 26.485 46.271 27.040 1.00108.39 C +ATOM 30844 CD LYS Q 49 25.021 46.528 27.353 1.00108.43 C +ATOM 30845 CE LYS Q 49 24.194 45.862 26.244 1.00117.90 C +ATOM 30846 NZ LYS Q 49 22.725 46.044 26.346 1.00134.34 N +ATOM 30847 N PRO Q 50 30.113 48.894 27.629 1.00119.30 N +ATOM 30848 CA PRO Q 50 31.032 49.813 28.272 1.00132.51 C +ATOM 30849 C PRO Q 50 30.419 50.484 29.516 1.00118.85 C +ATOM 30850 O PRO Q 50 29.197 50.423 29.736 1.00 51.98 O +ATOM 30851 CB PRO Q 50 31.309 50.845 27.166 1.00150.07 C +ATOM 30852 CG PRO Q 50 30.075 50.834 26.319 1.00111.81 C +ATOM 30853 CD PRO Q 50 29.567 49.433 26.366 1.00100.14 C +ATOM 30854 N TYR Q 51 31.277 51.154 30.285 1.00111.01 N +ATOM 30855 CA TYR Q 51 30.813 51.991 31.363 1.00 97.49 C +ATOM 30856 C TYR Q 51 29.739 52.929 30.863 1.00 94.37 C +ATOM 30857 O TYR Q 51 29.881 53.508 29.772 1.00113.51 O +ATOM 30858 CB TYR Q 51 31.962 52.808 31.952 1.00 99.42 C +ATOM 30859 CG TYR Q 51 31.582 53.408 33.294 1.00104.85 C +ATOM 30860 CD1 TYR Q 51 31.719 52.670 34.457 1.00105.80 C +ATOM 30861 CD2 TYR Q 51 31.068 54.689 33.397 1.00119.57 C +ATOM 30862 CE1 TYR Q 51 31.361 53.179 35.685 1.00 96.00 C +ATOM 30863 CE2 TYR Q 51 30.741 55.226 34.642 1.00116.65 C +ATOM 30864 CZ TYR Q 51 30.860 54.436 35.772 1.00104.67 C +ATOM 30865 OH TYR Q 51 30.531 54.894 37.022 1.00137.97 O +ATOM 30866 N PRO Q 52 28.653 53.099 31.643 1.00 91.61 N +ATOM 30867 CA PRO Q 52 28.383 52.611 32.991 1.00 87.17 C +ATOM 30868 C PRO Q 52 27.690 51.263 33.126 1.00116.72 C +ATOM 30869 O PRO Q 52 27.103 50.999 34.187 1.00138.88 O +ATOM 30870 CB PRO Q 52 27.480 53.700 33.554 1.00 90.47 C +ATOM 30871 CG PRO Q 52 26.675 54.154 32.365 1.00 99.55 C +ATOM 30872 CD PRO Q 52 27.599 54.034 31.180 1.00104.33 C +ATOM 30873 N ALA Q 53 27.681 50.431 32.078 1.00121.61 N +ATOM 30874 CA ALA Q 53 27.023 49.116 32.182 1.00136.58 C +ATOM 30875 C ALA Q 53 27.746 48.301 33.233 1.00146.07 C +ATOM 30876 O ALA Q 53 28.909 48.572 33.554 1.00149.42 O +ATOM 30877 CB ALA Q 53 26.996 48.374 30.841 1.00111.16 C +ATOM 30878 N SER Q 54 27.079 47.280 33.757 1.00156.93 N +ATOM 30879 CA SER Q 54 27.808 46.301 34.536 1.00154.17 C +ATOM 30880 C SER Q 54 28.941 45.724 33.687 1.00152.74 C +ATOM 30881 O SER Q 54 28.799 45.476 32.464 1.00236.23 O +ATOM 30882 CB SER Q 54 26.901 45.178 35.033 1.00180.63 C +ATOM 30883 OG SER Q 54 27.637 44.008 35.368 1.00206.80 O +ATOM 30884 N ASN Q 55 30.070 45.497 34.348 1.00 97.00 N +ATOM 30885 CA ASN Q 55 31.219 44.860 33.726 1.00 74.17 C +ATOM 30886 C ASN Q 55 30.853 43.575 33.000 1.00 78.76 C +ATOM 30887 O ASN Q 55 31.442 43.200 31.961 1.00 93.83 O +ATOM 30888 CB ASN Q 55 32.220 44.548 34.808 1.00 66.14 C +ATOM 30889 CG ASN Q 55 33.581 44.294 34.257 1.00 94.75 C +ATOM 30890 OD1 ASN Q 55 33.911 44.619 33.107 1.00118.00 O +ATOM 30891 ND2 ASN Q 55 34.411 43.747 35.093 1.00101.66 N +ATOM 30892 N PHE Q 56 29.792 42.937 33.500 1.00 92.95 N +ATOM 30893 CA PHE Q 56 29.384 41.605 33.064 1.00 91.04 C +ATOM 30894 C PHE Q 56 28.247 41.615 32.047 1.00103.70 C +ATOM 30895 O PHE Q 56 27.782 40.556 31.617 1.00130.07 O +ATOM 30896 CB PHE Q 56 28.906 40.791 34.265 1.00 85.62 C +ATOM 30897 CG PHE Q 56 29.921 40.693 35.377 1.00 74.95 C +ATOM 30898 CD1 PHE Q 56 31.166 40.091 35.183 1.00 82.01 C +ATOM 30899 CD2 PHE Q 56 29.645 41.205 36.596 1.00 78.35 C +ATOM 30900 CE1 PHE Q 56 32.131 40.078 36.185 1.00 62.07 C +ATOM 30901 CE2 PHE Q 56 30.582 41.117 37.629 1.00 84.83 C +ATOM 30902 CZ PHE Q 56 31.836 40.569 37.419 1.00 54.60 C +ATOM 30903 N SER Q 57 27.744 42.785 31.691 1.00109.58 N +ATOM 30904 CA SER Q 57 26.680 42.849 30.693 1.00106.37 C +ATOM 30905 C SER Q 57 27.253 42.593 29.293 1.00 99.62 C +ATOM 30906 O SER Q 57 28.062 43.351 28.763 1.00 68.19 O +ATOM 30907 CB SER Q 57 25.961 44.197 30.758 1.00140.76 C +ATOM 30908 OG SER Q 57 25.145 44.265 31.913 1.00175.58 O +ATOM 30909 N THR Q 58 26.815 41.510 28.679 1.00100.77 N +ATOM 30910 CA THR Q 58 27.287 41.166 27.351 1.00104.27 C +ATOM 30911 C THR Q 58 26.737 42.130 26.342 1.00110.88 C +ATOM 30912 O THR Q 58 25.603 42.617 26.458 1.00147.14 O +ATOM 30913 CB THR Q 58 26.835 39.747 26.970 1.00122.56 C +ATOM 30914 OG1 THR Q 58 25.398 39.657 26.971 1.00153.86 O +ATOM 30915 CG2 THR Q 58 27.368 38.772 27.961 1.00149.66 C +ATOM 30916 N ALA Q 59 27.435 42.289 25.243 1.00126.55 N +ATOM 30917 CA ALA Q 59 26.904 43.189 24.233 1.00173.08 C +ATOM 30918 C ALA Q 59 25.751 42.572 23.411 1.00175.62 C +ATOM 30919 O ALA Q 59 24.945 43.289 22.814 1.00108.54 O +ATOM 30920 CB ALA Q 59 28.006 43.628 23.318 1.00169.59 C +ATOM 30921 N VAL Q 60 25.668 41.241 23.416 1.00156.48 N +ATOM 30922 CA VAL Q 60 24.718 40.499 22.592 1.00113.76 C +ATOM 30923 C VAL Q 60 23.985 39.482 23.470 1.00 96.86 C +ATOM 30924 O VAL Q 60 24.607 38.839 24.314 1.00155.69 O +ATOM 30925 CB VAL Q 60 25.481 39.776 21.469 1.00104.53 C +ATOM 30926 CG1 VAL Q 60 24.540 38.962 20.577 1.00118.87 C +ATOM 30927 CG2 VAL Q 60 26.270 40.778 20.644 1.00105.26 C +ATOM 30928 N PRO Q 61 22.665 39.313 23.274 1.00103.02 N +ATOM 30929 CA PRO Q 61 21.955 38.287 24.040 1.00123.89 C +ATOM 30930 C PRO Q 61 22.432 36.860 23.770 1.00137.06 C +ATOM 30931 O PRO Q 61 22.811 36.522 22.635 1.00117.04 O +ATOM 30932 CB PRO Q 61 20.502 38.436 23.587 1.00131.15 C +ATOM 30933 CG PRO Q 61 20.584 39.080 22.252 1.00135.49 C +ATOM 30934 CD PRO Q 61 21.772 39.996 22.328 1.00122.33 C +ATOM 30935 N GLN Q 62 22.424 36.042 24.823 1.00132.33 N +ATOM 30936 CA GLN Q 62 23.002 34.694 24.769 1.00115.33 C +ATOM 30937 C GLN Q 62 21.968 33.704 24.305 1.00125.67 C +ATOM 30938 O GLN Q 62 21.943 32.572 24.759 1.00 67.43 O +ATOM 30939 CB GLN Q 62 23.513 34.279 26.148 1.00104.32 C +ATOM 30940 CG GLN Q 62 24.443 35.284 26.801 1.00 83.60 C +ATOM 30941 CD GLN Q 62 25.637 35.533 25.916 1.00 72.47 C +ATOM 30942 OE1 GLN Q 62 26.582 34.763 25.909 1.00 73.05 O +ATOM 30943 NE2 GLN Q 62 25.633 36.638 25.233 1.00100.20 N +ATOM 30944 N SER Q 63 21.080 34.157 23.425 1.00153.66 N +ATOM 30945 CA SER Q 63 19.812 33.472 23.189 1.00154.59 C +ATOM 30946 C SER Q 63 19.677 32.983 21.735 1.00126.36 C +ATOM 30947 O SER Q 63 18.598 32.565 21.308 1.00141.15 O +ATOM 30948 CB SER Q 63 18.643 34.399 23.595 1.00134.27 C +ATOM 30949 OG SER Q 63 18.577 35.593 22.815 1.00101.92 O +ATOM 30950 N ALA Q 64 20.772 33.084 20.984 1.00 77.35 N +ATOM 30951 CA ALA Q 64 20.761 32.860 19.557 1.00 69.31 C +ATOM 30952 C ALA Q 64 20.225 31.471 19.189 1.00 92.30 C +ATOM 30953 O ALA Q 64 19.479 31.316 18.199 1.00116.40 O +ATOM 30954 CB ALA Q 64 22.163 33.054 19.024 1.00 56.14 C +ATOM 30955 N THR Q 65 20.565 30.482 20.013 1.00 97.42 N +ATOM 30956 CA THR Q 65 20.146 29.105 19.810 1.00100.59 C +ATOM 30957 C THR Q 65 18.641 28.968 19.665 1.00106.41 C +ATOM 30958 O THR Q 65 18.141 28.362 18.698 1.00143.78 O +ATOM 30959 CB THR Q 65 20.528 28.276 21.016 1.00123.82 C +ATOM 30960 OG1 THR Q 65 21.814 28.698 21.463 1.00154.38 O +ATOM 30961 CG2 THR Q 65 20.545 26.788 20.659 1.00173.21 C +ATOM 30962 N ALA Q 66 17.904 29.579 20.591 1.00106.30 N +ATOM 30963 CA ALA Q 66 16.436 29.485 20.578 1.00115.18 C +ATOM 30964 C ALA Q 66 15.790 30.282 19.425 1.00102.26 C +ATOM 30965 O ALA Q 66 14.827 29.829 18.802 1.00 67.05 O +ATOM 30966 CB ALA Q 66 15.884 29.956 21.894 1.00117.73 C +ATOM 30967 N MET Q 67 16.426 31.392 19.062 1.00 92.12 N +ATOM 30968 CA MET Q 67 16.017 32.142 17.885 1.00 84.79 C +ATOM 30969 C MET Q 67 16.140 31.303 16.599 1.00 49.89 C +ATOM 30970 O MET Q 67 15.284 31.374 15.727 1.00 43.47 O +ATOM 30971 CB MET Q 67 16.848 33.449 17.756 1.00108.90 C +ATOM 30972 CG MET Q 67 16.586 34.508 18.834 1.00107.80 C +ATOM 30973 SD MET Q 67 17.834 35.848 18.769 1.00 57.90 S +ATOM 30974 CE MET Q 67 17.175 36.970 20.002 1.00 87.51 C +ATOM 30975 N LEU Q 68 17.276 30.645 16.435 1.00 36.53 N +ATOM 30976 CA LEU Q 68 17.499 29.850 15.261 1.00 40.58 C +ATOM 30977 C LEU Q 68 16.502 28.730 15.174 1.00 46.72 C +ATOM 30978 O LEU Q 68 15.968 28.465 14.119 1.00 76.09 O +ATOM 30979 CB LEU Q 68 18.886 29.226 15.262 1.00 61.66 C +ATOM 30980 CG LEU Q 68 19.098 28.138 14.160 1.00 60.08 C +ATOM 30981 CD1 LEU Q 68 19.059 28.812 12.801 1.00 73.06 C +ATOM 30982 CD2 LEU Q 68 20.410 27.384 14.320 1.00 60.97 C +ATOM 30983 N VAL Q 69 16.254 28.035 16.278 1.00 66.45 N +ATOM 30984 CA VAL Q 69 15.265 26.938 16.302 1.00 67.14 C +ATOM 30985 C VAL Q 69 13.889 27.474 15.895 1.00 94.50 C +ATOM 30986 O VAL Q 69 13.189 26.869 15.080 1.00 89.51 O +ATOM 30987 CB VAL Q 69 15.133 26.256 17.694 1.00 59.30 C +ATOM 30988 CG1 VAL Q 69 13.989 25.278 17.681 1.00 53.42 C +ATOM 30989 CG2 VAL Q 69 16.423 25.532 18.099 1.00 66.34 C +ATOM 30990 N THR Q 70 13.539 28.645 16.425 1.00122.63 N +ATOM 30991 CA THR Q 70 12.261 29.284 16.111 1.00127.34 C +ATOM 30992 C THR Q 70 12.158 29.681 14.641 1.00 97.62 C +ATOM 30993 O THR Q 70 11.169 29.393 13.973 1.00116.31 O +ATOM 30994 CB THR Q 70 12.047 30.523 16.986 1.00125.45 C +ATOM 30995 OG1 THR Q 70 12.159 30.130 18.365 1.00177.36 O +ATOM 30996 CG2 THR Q 70 10.658 31.140 16.716 1.00105.94 C +ATOM 30997 N ALA Q 71 13.238 30.234 14.117 1.00 72.76 N +ATOM 30998 CA ALA Q 71 13.289 30.563 12.702 1.00 71.52 C +ATOM 30999 C ALA Q 71 13.138 29.313 11.840 1.00 61.70 C +ATOM 31000 O ALA Q 71 12.468 29.327 10.799 1.00 75.57 O +ATOM 31001 CB ALA Q 71 14.586 31.324 12.368 1.00 71.19 C +ATOM 31002 N LEU Q 72 13.834 28.260 12.222 1.00 63.66 N +ATOM 31003 CA LEU Q 72 13.792 27.003 11.467 1.00 84.66 C +ATOM 31004 C LEU Q 72 12.376 26.468 11.440 1.00 88.84 C +ATOM 31005 O LEU Q 72 12.017 25.707 10.548 1.00 84.28 O +ATOM 31006 CB LEU Q 72 14.746 25.951 12.076 1.00 91.33 C +ATOM 31007 CG LEU Q 72 16.240 26.254 11.908 1.00 92.12 C +ATOM 31008 CD1 LEU Q 72 17.027 25.422 12.896 1.00 91.30 C +ATOM 31009 CD2 LEU Q 72 16.720 26.012 10.489 1.00 76.59 C +ATOM 31010 N LYS Q 73 11.590 26.806 12.460 1.00 89.84 N +ATOM 31011 CA LYS Q 73 10.217 26.298 12.537 1.00 93.75 C +ATOM 31012 C LYS Q 73 9.299 27.170 11.703 1.00102.52 C +ATOM 31013 O LYS Q 73 8.445 26.651 11.001 1.00130.19 O +ATOM 31014 CB LYS Q 73 9.715 26.220 13.986 1.00 80.50 C +ATOM 31015 CG LYS Q 73 8.407 25.435 14.164 1.00 60.53 C +ATOM 31016 CD LYS Q 73 7.962 25.415 15.636 1.00 59.63 C +ATOM 31017 CE LYS Q 73 6.457 25.305 15.785 1.00 62.48 C +ATOM 31018 NZ LYS Q 73 6.018 24.029 16.402 1.00 57.18 N +ATOM 31019 N ASP Q 74 9.451 28.483 11.830 1.00 97.20 N +ATOM 31020 CA ASP Q 74 8.550 29.410 11.185 1.00110.71 C +ATOM 31021 C ASP Q 74 8.611 29.231 9.678 1.00105.61 C +ATOM 31022 O ASP Q 74 7.641 29.538 8.974 1.00116.48 O +ATOM 31023 CB ASP Q 74 8.893 30.864 11.588 1.00104.22 C +ATOM 31024 CG ASP Q 74 8.567 31.169 13.060 1.00 95.72 C +ATOM 31025 OD1 ASP Q 74 7.600 30.578 13.627 1.00119.62 O +ATOM 31026 OD2 ASP Q 74 9.208 32.077 13.621 1.00 86.51 O +ATOM 31027 N SER Q 75 9.776 28.819 9.185 1.00 91.68 N +ATOM 31028 CA SER Q 75 10.010 28.688 7.735 1.00 98.87 C +ATOM 31029 C SER Q 75 9.092 27.658 7.083 1.00 88.45 C +ATOM 31030 O SER Q 75 8.856 27.702 5.881 1.00 61.21 O +ATOM 31031 CB SER Q 75 11.474 28.316 7.451 1.00 95.68 C +ATOM 31032 OG SER Q 75 11.678 26.922 7.534 1.00 79.87 O +ATOM 31033 N ARG Q 76 8.622 26.710 7.892 1.00103.61 N +ATOM 31034 CA ARG Q 76 7.818 25.572 7.431 1.00101.93 C +ATOM 31035 C ARG Q 76 8.573 24.740 6.418 1.00 69.31 C +ATOM 31036 O ARG Q 76 8.002 24.178 5.493 1.00 61.20 O +ATOM 31037 CB ARG Q 76 6.510 26.052 6.831 1.00138.67 C +ATOM 31038 CG ARG Q 76 5.626 26.824 7.796 1.00159.74 C +ATOM 31039 CD ARG Q 76 4.328 27.224 7.103 1.00167.40 C +ATOM 31040 NE ARG Q 76 4.565 28.245 6.080 1.00182.86 N +ATOM 31041 CZ ARG Q 76 4.766 28.005 4.786 1.00166.96 C +ATOM 31042 NH1 ARG Q 76 4.762 26.762 4.306 1.00142.72 N +ATOM 31043 NH2 ARG Q 76 4.987 29.026 3.968 1.00160.68 N +ATOM 31044 N TRP Q 77 9.868 24.641 6.637 1.00 74.25 N +ATOM 31045 CA TRP Q 77 10.704 23.665 5.957 1.00118.77 C +ATOM 31046 C TRP Q 77 11.210 22.540 6.913 1.00119.35 C +ATOM 31047 O TRP Q 77 11.436 21.400 6.497 1.00 91.04 O +ATOM 31048 CB TRP Q 77 11.887 24.406 5.333 1.00125.23 C +ATOM 31049 CG TRP Q 77 11.636 24.860 3.962 1.00114.85 C +ATOM 31050 CD1 TRP Q 77 10.878 25.909 3.582 1.00124.77 C +ATOM 31051 CD2 TRP Q 77 12.162 24.281 2.768 1.00113.52 C +ATOM 31052 NE1 TRP Q 77 10.887 26.021 2.221 1.00155.86 N +ATOM 31053 CE2 TRP Q 77 11.677 25.033 1.697 1.00127.53 C +ATOM 31054 CE3 TRP Q 77 13.023 23.215 2.503 1.00143.98 C +ATOM 31055 CZ2 TRP Q 77 12.021 24.760 0.368 1.00142.00 C +ATOM 31056 CZ3 TRP Q 77 13.344 22.930 1.183 1.00170.00 C +ATOM 31057 CH2 TRP Q 77 12.850 23.708 0.133 1.00152.95 C +ATOM 31058 N PHE Q 78 11.438 22.902 8.174 1.00115.65 N +ATOM 31059 CA PHE Q 78 12.094 22.042 9.147 1.00 96.68 C +ATOM 31060 C PHE Q 78 11.191 21.782 10.355 1.00104.20 C +ATOM 31061 O PHE Q 78 10.509 22.694 10.850 1.00 83.07 O +ATOM 31062 CB PHE Q 78 13.384 22.711 9.655 1.00117.00 C +ATOM 31063 CG PHE Q 78 14.362 23.083 8.569 1.00112.44 C +ATOM 31064 CD1 PHE Q 78 15.166 22.117 7.961 1.00 92.77 C +ATOM 31065 CD2 PHE Q 78 14.540 24.415 8.229 1.00101.32 C +ATOM 31066 CE1 PHE Q 78 16.077 22.467 6.990 1.00 73.39 C +ATOM 31067 CE2 PHE Q 78 15.460 24.767 7.267 1.00 92.78 C +ATOM 31068 CZ PHE Q 78 16.212 23.786 6.630 1.00 72.80 C +ATOM 31069 N ILE Q 79 11.298 20.565 10.888 1.00123.16 N +ATOM 31070 CA ILE Q 79 10.823 20.213 12.239 1.00112.63 C +ATOM 31071 C ILE Q 79 12.009 20.185 13.186 1.00 79.21 C +ATOM 31072 O ILE Q 79 13.047 19.581 12.844 1.00 76.98 O +ATOM 31073 CB ILE Q 79 10.239 18.800 12.269 1.00126.24 C +ATOM 31074 CG1 ILE Q 79 9.247 18.589 11.128 1.00149.09 C +ATOM 31075 CG2 ILE Q 79 9.570 18.541 13.602 1.00142.88 C +ATOM 31076 CD1 ILE Q 79 9.054 17.130 10.750 1.00128.06 C +ATOM 31077 N PRO Q 80 11.951 21.016 14.228 1.00 74.58 N +ATOM 31078 CA PRO Q 80 13.133 21.009 15.022 1.00 91.72 C +ATOM 31079 C PRO Q 80 12.931 19.964 16.051 1.00 67.67 C +ATOM 31080 O PRO Q 80 11.906 19.953 16.712 1.00 61.12 O +ATOM 31081 CB PRO Q 80 13.186 22.440 15.611 1.00110.51 C +ATOM 31082 CG PRO Q 80 12.460 23.268 14.622 1.00 98.96 C +ATOM 31083 CD PRO Q 80 11.327 22.353 14.231 1.00 96.97 C +ATOM 31084 N LEU Q 81 13.988 19.223 16.300 1.00 56.81 N +ATOM 31085 CA LEU Q 81 14.027 18.377 17.416 1.00 76.65 C +ATOM 31086 C LEU Q 81 14.699 19.097 18.588 1.00 80.51 C +ATOM 31087 O LEU Q 81 15.710 19.798 18.423 1.00 51.40 O +ATOM 31088 CB LEU Q 81 14.731 17.083 17.027 1.00111.57 C +ATOM 31089 CG LEU Q 81 14.076 16.474 15.781 1.00115.84 C +ATOM 31090 CD1 LEU Q 81 14.909 15.287 15.353 1.00132.03 C +ATOM 31091 CD2 LEU Q 81 12.646 16.057 16.067 1.00 88.79 C +ATOM 31092 N GLU Q 82 14.123 18.864 19.778 1.00 98.23 N +ATOM 31093 CA GLU Q 82 14.608 19.450 21.014 1.00 85.89 C +ATOM 31094 C GLU Q 82 15.907 18.742 21.496 1.00120.80 C +ATOM 31095 O GLU Q 82 15.880 17.620 22.064 1.00140.26 O +ATOM 31096 CB GLU Q 82 13.517 19.460 22.101 1.00 54.72 C +ATOM 31097 CG GLU Q 82 13.950 20.101 23.413 1.00 63.24 C +ATOM 31098 CD GLU Q 82 14.145 21.637 23.352 1.00 64.72 C +ATOM 31099 OE1 GLU Q 82 14.878 22.167 22.482 1.00 58.81 O +ATOM 31100 OE2 GLU Q 82 13.716 22.314 24.314 1.00 67.11 O +ATOM 31101 N ARG Q 83 17.027 19.462 21.350 1.00 96.84 N +ATOM 31102 CA ARG Q 83 18.292 19.080 21.961 1.00 95.22 C +ATOM 31103 C ARG Q 83 18.860 20.107 22.994 1.00108.46 C +ATOM 31104 O ARG Q 83 19.729 19.754 23.796 1.00 83.67 O +ATOM 31105 CB ARG Q 83 19.290 18.809 20.842 1.00 81.76 C +ATOM 31106 CG ARG Q 83 18.791 17.810 19.838 1.00 76.05 C +ATOM 31107 CD ARG Q 83 18.717 16.413 20.420 1.00 97.17 C +ATOM 31108 NE ARG Q 83 18.466 15.487 19.323 1.00115.06 N +ATOM 31109 CZ ARG Q 83 17.293 14.920 19.028 1.00105.00 C +ATOM 31110 NH1 ARG Q 83 16.239 15.069 19.828 1.00 79.23 N +ATOM 31111 NH2 ARG Q 83 17.213 14.147 17.936 1.00103.94 N +ATOM 31112 N GLN Q 84 18.396 21.365 22.978 1.00111.28 N +ATOM 31113 CA GLN Q 84 18.948 22.367 23.908 1.00103.30 C +ATOM 31114 C GLN Q 84 18.666 21.949 25.332 1.00 77.60 C +ATOM 31115 O GLN Q 84 19.544 21.976 26.170 1.00109.46 O +ATOM 31116 CB GLN Q 84 18.424 23.780 23.662 1.00115.29 C +ATOM 31117 CG GLN Q 84 19.421 24.896 24.038 1.00115.82 C +ATOM 31118 CD GLN Q 84 18.833 26.290 23.868 1.00161.25 C +ATOM 31119 OE1 GLN Q 84 18.020 26.533 22.963 1.00259.80 O +ATOM 31120 NE2 GLN Q 84 19.198 27.200 24.754 1.00146.18 N +ATOM 31121 N GLY Q 85 17.516 21.369 25.574 1.00 77.78 N +ATOM 31122 CA GLY Q 85 17.257 20.824 26.914 1.00105.85 C +ATOM 31123 C GLY Q 85 17.186 19.307 26.958 1.00114.26 C +ATOM 31124 O GLY Q 85 16.364 18.751 27.702 1.00125.54 O +ATOM 31125 N LEU Q 86 18.075 18.627 26.220 1.00 91.23 N +ATOM 31126 CA LEU Q 86 17.960 17.171 26.028 1.00 74.11 C +ATOM 31127 C LEU Q 86 17.983 16.385 27.356 1.00 82.69 C +ATOM 31128 O LEU Q 86 17.275 15.384 27.521 1.00 74.57 O +ATOM 31129 CB LEU Q 86 19.078 16.647 25.147 1.00 76.82 C +ATOM 31130 CG LEU Q 86 19.249 15.126 24.939 1.00 95.98 C +ATOM 31131 CD1 LEU Q 86 18.017 14.486 24.311 1.00106.39 C +ATOM 31132 CD2 LEU Q 86 20.469 14.847 24.065 1.00107.79 C +ATOM 31133 N GLN Q 87 18.745 16.874 28.329 1.00 90.74 N +ATOM 31134 CA GLN Q 87 18.904 16.151 29.593 1.00 94.94 C +ATOM 31135 C GLN Q 87 17.561 15.974 30.359 1.00 63.34 C +ATOM 31136 O GLN Q 87 17.223 14.905 30.860 1.00 65.92 O +ATOM 31137 CB GLN Q 87 19.972 16.859 30.451 1.00120.91 C +ATOM 31138 CG GLN Q 87 20.813 15.906 31.292 1.00135.16 C +ATOM 31139 CD GLN Q 87 21.238 14.648 30.535 1.00145.84 C +ATOM 31140 OE1 GLN Q 87 21.891 14.719 29.493 1.00136.84 O +ATOM 31141 NE2 GLN Q 87 20.876 13.481 31.073 1.00162.49 N +ATOM 31142 N ASN Q 88 16.817 17.047 30.455 1.00 52.38 N +ATOM 31143 CA ASN Q 88 15.528 17.012 31.073 1.00 63.13 C +ATOM 31144 C ASN Q 88 14.579 16.066 30.342 1.00 76.07 C +ATOM 31145 O ASN Q 88 13.661 15.484 30.944 1.00 86.61 O +ATOM 31146 CB ASN Q 88 14.917 18.424 31.033 1.00 97.27 C +ATOM 31147 CG ASN Q 88 15.784 19.431 31.722 1.00 75.67 C +ATOM 31148 OD1 ASN Q 88 16.398 19.097 32.722 1.00 40.77 O +ATOM 31149 ND2 ASN Q 88 15.896 20.648 31.144 1.00 78.96 N +ATOM 31150 N LEU Q 89 14.665 16.075 29.012 1.00 78.61 N +ATOM 31151 CA LEU Q 89 13.782 15.286 28.178 1.00 67.96 C +ATOM 31152 C LEU Q 89 14.006 13.800 28.565 1.00 78.85 C +ATOM 31153 O LEU Q 89 13.054 13.023 28.741 1.00 68.77 O +ATOM 31154 CB LEU Q 89 14.095 15.574 26.693 1.00 53.82 C +ATOM 31155 CG LEU Q 89 13.022 15.431 25.636 1.00 48.55 C +ATOM 31156 CD1 LEU Q 89 13.351 14.297 24.705 1.00 58.59 C +ATOM 31157 CD2 LEU Q 89 11.655 15.155 26.262 1.00 51.17 C +ATOM 31158 N LEU Q 90 15.272 13.440 28.732 1.00 86.11 N +ATOM 31159 CA LEU Q 90 15.640 12.060 29.035 1.00 92.32 C +ATOM 31160 C LEU Q 90 15.206 11.695 30.451 1.00 93.37 C +ATOM 31161 O LEU Q 90 14.873 10.539 30.748 1.00112.91 O +ATOM 31162 CB LEU Q 90 17.149 11.871 28.886 1.00 81.09 C +ATOM 31163 CG LEU Q 90 17.656 12.140 27.494 1.00 85.58 C +ATOM 31164 CD1 LEU Q 90 19.155 12.379 27.544 1.00 82.89 C +ATOM 31165 CD2 LEU Q 90 17.292 10.966 26.587 1.00114.75 C +ATOM 31166 N ASN Q 91 15.207 12.693 31.319 1.00 80.91 N +ATOM 31167 CA ASN Q 91 14.771 12.486 32.666 1.00 77.88 C +ATOM 31168 C ASN Q 91 13.275 12.217 32.754 1.00116.62 C +ATOM 31169 O ASN Q 91 12.847 11.296 33.453 1.00141.94 O +ATOM 31170 CB ASN Q 91 15.136 13.669 33.523 1.00 79.57 C +ATOM 31171 CG ASN Q 91 15.858 13.203 34.748 1.00 75.88 C +ATOM 31172 OD1 ASN Q 91 16.875 12.535 34.611 1.00 60.87 O +ATOM 31173 ND2 ASN Q 91 15.303 13.453 35.952 1.00 99.77 N +ATOM 31174 N GLU Q 92 12.477 13.054 32.096 1.00112.02 N +ATOM 31175 CA GLU Q 92 11.043 12.844 32.095 1.00 99.94 C +ATOM 31176 C GLU Q 92 10.748 11.442 31.579 1.00 78.15 C +ATOM 31177 O GLU Q 92 9.764 10.794 31.984 1.00 74.34 O +ATOM 31178 CB GLU Q 92 10.319 13.918 31.262 1.00110.16 C +ATOM 31179 CG GLU Q 92 9.838 15.114 32.064 1.00 96.27 C +ATOM 31180 CD GLU Q 92 8.979 14.725 33.279 1.00102.26 C +ATOM 31181 OE1 GLU Q 92 7.903 14.064 33.135 1.00 72.43 O +ATOM 31182 OE2 GLU Q 92 9.357 15.145 34.398 1.00 89.26 O +ATOM 31183 N ARG Q 93 11.503 11.037 30.572 1.00 63.34 N +ATOM 31184 CA ARG Q 93 11.284 9.732 29.997 1.00 91.83 C +ATOM 31185 C ARG Q 93 11.643 8.626 31.018 1.00114.38 C +ATOM 31186 O ARG Q 93 11.028 7.556 31.035 1.00138.79 O +ATOM 31187 CB ARG Q 93 12.037 9.629 28.663 1.00 84.50 C +ATOM 31188 CG ARG Q 93 11.414 10.507 27.594 1.00 67.36 C +ATOM 31189 CD ARG Q 93 12.311 10.715 26.385 1.00 86.64 C +ATOM 31190 NE ARG Q 93 11.929 9.873 25.255 1.00 97.86 N +ATOM 31191 CZ ARG Q 93 12.514 8.727 24.924 1.00109.87 C +ATOM 31192 NH1 ARG Q 93 13.517 8.227 25.639 1.00126.66 N +ATOM 31193 NH2 ARG Q 93 12.094 8.087 23.846 1.00123.29 N +ATOM 31194 N LYS Q 94 12.635 8.875 31.868 1.00116.38 N +ATOM 31195 CA LYS Q 94 12.972 7.917 32.924 1.00106.14 C +ATOM 31196 C LYS Q 94 11.802 7.822 33.876 1.00 94.71 C +ATOM 31197 O LYS Q 94 11.466 6.712 34.347 1.00 84.11 O +ATOM 31198 CB LYS Q 94 14.200 8.367 33.701 1.00132.45 C +ATOM 31199 CG LYS Q 94 15.539 7.893 33.152 1.00144.47 C +ATOM 31200 CD LYS Q 94 16.677 8.575 33.906 1.00149.68 C +ATOM 31201 CE LYS Q 94 18.005 7.840 33.786 1.00128.80 C +ATOM 31202 NZ LYS Q 94 19.117 8.719 34.240 1.00126.35 N +ATOM 31203 N ILE Q 95 11.165 8.974 34.141 1.00 69.99 N +ATOM 31204 CA ILE Q 95 10.097 9.012 35.140 1.00 74.99 C +ATOM 31205 C ILE Q 95 8.835 8.322 34.624 1.00 80.27 C +ATOM 31206 O ILE Q 95 8.145 7.575 35.383 1.00 39.44 O +ATOM 31207 CB ILE Q 95 9.715 10.416 35.579 1.00 55.71 C +ATOM 31208 CG1 ILE Q 95 10.939 11.203 35.953 1.00 62.47 C +ATOM 31209 CG2 ILE Q 95 8.829 10.290 36.807 1.00 65.52 C +ATOM 31210 CD1 ILE Q 95 10.658 12.477 36.708 1.00 88.92 C +ATOM 31211 N ILE Q 96 8.596 8.530 33.323 1.00 81.39 N +ATOM 31212 CA ILE Q 96 7.543 7.811 32.597 1.00 80.72 C +ATOM 31213 C ILE Q 96 7.747 6.325 32.695 1.00 87.97 C +ATOM 31214 O ILE Q 96 6.902 5.613 33.221 1.00 82.74 O +ATOM 31215 CB ILE Q 96 7.492 8.190 31.108 1.00 67.64 C +ATOM 31216 CG1 ILE Q 96 7.050 9.642 30.981 1.00 90.74 C +ATOM 31217 CG2 ILE Q 96 6.486 7.320 30.398 1.00 54.65 C +ATOM 31218 CD1 ILE Q 96 6.895 10.091 29.551 1.00109.08 C +ATOM 31219 N ARG Q 97 8.909 5.862 32.233 1.00106.36 N +ATOM 31220 CA ARG Q 97 9.209 4.418 32.210 1.00 98.71 C +ATOM 31221 C ARG Q 97 9.165 3.784 33.613 1.00 87.77 C +ATOM 31222 O ARG Q 97 8.770 2.621 33.768 1.00 66.43 O +ATOM 31223 CB ARG Q 97 10.570 4.143 31.576 1.00100.31 C +ATOM 31224 CG ARG Q 97 10.512 3.650 30.141 1.00110.95 C +ATOM 31225 CD ARG Q 97 11.908 3.333 29.619 1.00110.85 C +ATOM 31226 NE ARG Q 97 12.622 4.529 29.176 1.00 84.74 N +ATOM 31227 CZ ARG Q 97 12.697 4.931 27.907 1.00 86.14 C +ATOM 31228 NH1 ARG Q 97 12.117 4.242 26.913 1.00 69.76 N +ATOM 31229 NH2 ARG Q 97 13.369 6.033 27.618 1.00 95.94 N +ATOM 31230 N ALA Q 98 9.507 4.572 34.631 1.00 64.19 N +ATOM 31231 CA ALA Q 98 9.433 4.098 35.991 1.00 64.61 C +ATOM 31232 C ALA Q 98 7.983 4.015 36.468 1.00 67.77 C +ATOM 31233 O ALA Q 98 7.639 3.201 37.343 1.00 45.56 O +ATOM 31234 CB ALA Q 98 10.262 4.996 36.887 1.00 57.96 C +ATOM 31235 N ALA Q 99 7.149 4.900 35.915 1.00 90.38 N +ATOM 31236 CA ALA Q 99 5.729 4.968 36.275 1.00 96.60 C +ATOM 31237 C ALA Q 99 4.972 3.722 35.825 1.00 80.35 C +ATOM 31238 O ALA Q 99 4.234 3.110 36.585 1.00 48.10 O +ATOM 31239 CB ALA Q 99 5.087 6.232 35.691 1.00 81.33 C +ATOM 31240 N GLN Q 100 5.137 3.387 34.556 1.00112.23 N +ATOM 31241 CA GLN Q 100 4.208 2.479 33.882 1.00134.17 C +ATOM 31242 C GLN Q 100 4.797 1.107 33.621 1.00125.30 C +ATOM 31243 O GLN Q 100 4.154 0.273 32.971 1.00143.17 O +ATOM 31244 CB GLN Q 100 3.688 3.095 32.564 1.00138.55 C +ATOM 31245 CG GLN Q 100 4.736 3.803 31.713 1.00110.06 C +ATOM 31246 CD GLN Q 100 4.183 4.925 30.846 1.00 97.52 C +ATOM 31247 OE1 GLN Q 100 3.558 5.890 31.326 1.00 95.08 O +ATOM 31248 NE2 GLN Q 100 4.373 4.777 29.547 1.00115.72 N +ATOM 31249 N GLU Q 101 5.997 0.861 34.146 1.00 98.76 N +ATOM 31250 CA GLU Q 101 6.653 -0.439 33.953 1.00110.00 C +ATOM 31251 C GLU Q 101 5.931 -1.622 34.645 1.00102.43 C +ATOM 31252 O GLU Q 101 6.051 -2.765 34.203 1.00 72.30 O +ATOM 31253 CB GLU Q 101 8.109 -0.383 34.407 1.00 98.21 C +ATOM 31254 CG GLU Q 101 8.307 0.125 35.822 1.00115.70 C +ATOM 31255 CD GLU Q 101 9.769 0.099 36.260 1.00112.08 C +ATOM 31256 OE1 GLU Q 101 10.641 -0.018 35.378 1.00 93.30 O +ATOM 31257 OE2 GLU Q 101 10.031 0.142 37.491 1.00 93.38 O +ATOM 31258 N ASN Q 102 5.152 -1.333 35.685 1.00 80.03 N +ATOM 31259 CA ASN Q 102 4.458 -2.370 36.409 1.00 63.32 C +ATOM 31260 C ASN Q 102 3.035 -2.633 35.892 1.00 93.08 C +ATOM 31261 O ASN Q 102 2.335 -3.527 36.399 1.00 79.90 O +ATOM 31262 CB ASN Q 102 4.374 -2.006 37.877 1.00 54.45 C +ATOM 31263 CG ASN Q 102 5.668 -2.125 38.568 1.00 50.48 C +ATOM 31264 OD1 ASN Q 102 6.180 -3.242 38.808 1.00 59.65 O +ATOM 31265 ND2 ASN Q 102 6.294 -0.972 38.805 1.00 61.55 N +ATOM 31266 N GLY Q 103 2.582 -1.861 34.903 1.00115.31 N +ATOM 31267 CA GLY Q 103 1.229 -2.048 34.356 1.00111.30 C +ATOM 31268 C GLY Q 103 0.114 -1.866 35.376 1.00 85.52 C +ATOM 31269 O GLY Q 103 -0.921 -2.541 35.321 1.00 88.53 O +ATOM 31270 N THR Q 104 0.332 -0.970 36.319 1.00 67.75 N +ATOM 31271 CA THR Q 104 -0.733 -0.542 37.178 1.00 79.94 C +ATOM 31272 C THR Q 104 -1.257 0.793 36.693 1.00100.61 C +ATOM 31273 O THR Q 104 -2.443 1.078 36.881 1.00168.26 O +ATOM 31274 CB THR Q 104 -0.298 -0.416 38.648 1.00 90.96 C +ATOM 31275 OG1 THR Q 104 0.693 0.614 38.802 1.00104.61 O +ATOM 31276 CG2 THR Q 104 0.253 -1.746 39.144 1.00 89.33 C +ATOM 31277 N VAL Q 105 -0.426 1.585 36.009 1.00104.01 N +ATOM 31278 CA VAL Q 105 -0.834 2.944 35.630 1.00115.32 C +ATOM 31279 C VAL Q 105 -2.083 2.944 34.740 1.00117.68 C +ATOM 31280 O VAL Q 105 -2.262 2.075 33.878 1.00122.12 O +ATOM 31281 CB VAL Q 105 0.301 3.769 34.971 1.00141.24 C +ATOM 31282 CG1 VAL Q 105 -0.240 4.760 33.935 1.00145.44 C +ATOM 31283 CG2 VAL Q 105 1.108 4.530 36.031 1.00159.14 C +ATOM 31284 N ALA Q 106 -2.972 3.895 35.026 1.00123.45 N +ATOM 31285 CA ALA Q 106 -4.307 3.945 34.443 1.00123.44 C +ATOM 31286 C ALA Q 106 -4.216 4.118 32.937 1.00113.83 C +ATOM 31287 O ALA Q 106 -3.466 4.965 32.447 1.00136.90 O +ATOM 31288 CB ALA Q 106 -5.109 5.085 35.075 1.00126.88 C +ATOM 31289 N ILE Q 107 -5.011 3.336 32.211 1.00114.60 N +ATOM 31290 CA ILE Q 107 -4.953 3.302 30.746 1.00137.76 C +ATOM 31291 C ILE Q 107 -5.195 4.681 30.081 1.00136.52 C +ATOM 31292 O ILE Q 107 -4.651 4.983 29.019 1.00103.33 O +ATOM 31293 CB ILE Q 107 -5.946 2.248 30.191 1.00137.19 C +ATOM 31294 CG1 ILE Q 107 -5.673 1.962 28.709 1.00134.23 C +ATOM 31295 CG2 ILE Q 107 -7.391 2.698 30.396 1.00140.79 C +ATOM 31296 CD1 ILE Q 107 -4.264 1.486 28.402 1.00103.08 C +ATOM 31297 N ASN Q 108 -6.008 5.512 30.725 1.00154.26 N +ATOM 31298 CA ASN Q 108 -6.240 6.888 30.277 1.00158.96 C +ATOM 31299 C ASN Q 108 -5.001 7.753 30.482 1.00161.04 C +ATOM 31300 O ASN Q 108 -4.721 8.661 29.702 1.00219.76 O +ATOM 31301 CB ASN Q 108 -7.410 7.518 31.049 1.00174.77 C +ATOM 31302 CG ASN Q 108 -8.450 6.498 31.476 1.00201.60 C +ATOM 31303 OD1 ASN Q 108 -9.362 6.170 30.717 1.00236.63 O +ATOM 31304 ND2 ASN Q 108 -8.311 5.982 32.695 1.00198.65 N +ATOM 31305 N ASN Q 109 -4.292 7.486 31.570 1.00153.85 N +ATOM 31306 CA ASN Q 109 -3.154 8.295 31.991 1.00151.66 C +ATOM 31307 C ASN Q 109 -1.843 7.865 31.333 1.00149.31 C +ATOM 31308 O ASN Q 109 -0.865 8.623 31.323 1.00158.93 O +ATOM 31309 CB ASN Q 109 -3.006 8.222 33.512 1.00154.66 C +ATOM 31310 CG ASN Q 109 -3.216 9.564 34.181 1.00165.46 C +ATOM 31311 OD1 ASN Q 109 -2.285 10.131 34.749 1.00169.16 O +ATOM 31312 ND2 ASN Q 109 -4.426 10.103 34.074 1.00166.87 N +ATOM 31313 N ARG Q 110 -1.848 6.660 30.761 1.00131.59 N +ATOM 31314 CA ARG Q 110 -0.647 6.032 30.188 1.00106.32 C +ATOM 31315 C ARG Q 110 0.003 6.922 29.121 1.00102.22 C +ATOM 31316 O ARG Q 110 -0.686 7.460 28.256 1.00 95.03 O +ATOM 31317 CB ARG Q 110 -1.031 4.675 29.565 1.00 93.27 C +ATOM 31318 CG ARG Q 110 0.101 3.673 29.453 1.00 89.06 C +ATOM 31319 CD ARG Q 110 -0.380 2.243 29.650 1.00 83.25 C +ATOM 31320 NE ARG Q 110 -0.810 1.624 28.391 1.00 99.83 N +ATOM 31321 CZ ARG Q 110 -0.225 0.557 27.815 1.00108.44 C +ATOM 31322 NH1 ARG Q 110 0.790 -0.089 28.406 1.00 91.32 N +ATOM 31323 NH2 ARG Q 110 -0.664 0.124 26.629 1.00 93.32 N +ATOM 31324 N ILE Q 111 1.325 7.075 29.178 1.00 93.89 N +ATOM 31325 CA ILE Q 111 2.046 7.786 28.123 1.00 88.53 C +ATOM 31326 C ILE Q 111 2.842 6.820 27.282 1.00 84.85 C +ATOM 31327 O ILE Q 111 3.768 6.203 27.788 1.00 92.77 O +ATOM 31328 CB ILE Q 111 3.000 8.831 28.692 1.00 89.63 C +ATOM 31329 CG1 ILE Q 111 2.196 9.902 29.436 1.00119.29 C +ATOM 31330 CG2 ILE Q 111 3.810 9.469 27.568 1.00 86.72 C +ATOM 31331 CD1 ILE Q 111 3.033 10.838 30.292 1.00149.05 C +ATOM 31332 N PRO Q 112 2.495 6.691 25.990 1.00 94.15 N +ATOM 31333 CA PRO Q 112 3.216 5.777 25.123 1.00103.07 C +ATOM 31334 C PRO Q 112 4.560 6.363 24.674 1.00120.56 C +ATOM 31335 O PRO Q 112 4.623 7.506 24.190 1.00113.68 O +ATOM 31336 CB PRO Q 112 2.273 5.621 23.935 1.00104.14 C +ATOM 31337 CG PRO Q 112 1.598 6.950 23.828 1.00109.24 C +ATOM 31338 CD PRO Q 112 1.570 7.544 25.220 1.00112.24 C +ATOM 31339 N LEU Q 113 5.620 5.583 24.851 1.00115.35 N +ATOM 31340 CA LEU Q 113 6.960 6.064 24.597 1.00105.34 C +ATOM 31341 C LEU Q 113 7.525 5.495 23.310 1.00108.70 C +ATOM 31342 O LEU Q 113 7.381 4.318 22.992 1.00140.02 O +ATOM 31343 CB LEU Q 113 7.880 5.758 25.782 1.00 96.77 C +ATOM 31344 CG LEU Q 113 7.883 6.805 26.900 1.00 86.95 C +ATOM 31345 CD1 LEU Q 113 8.905 6.393 27.924 1.00 79.44 C +ATOM 31346 CD2 LEU Q 113 8.201 8.199 26.370 1.00100.67 C +ATOM 31347 N GLN Q 114 8.245 6.350 22.612 1.00 97.61 N +ATOM 31348 CA GLN Q 114 8.674 6.086 21.270 1.00103.92 C +ATOM 31349 C GLN Q 114 10.098 6.564 21.253 1.00111.34 C +ATOM 31350 O GLN Q 114 10.438 7.528 21.954 1.00169.74 O +ATOM 31351 CB GLN Q 114 7.814 6.891 20.295 1.00103.65 C +ATOM 31352 CG GLN Q 114 7.651 6.278 18.915 1.00116.22 C +ATOM 31353 CD GLN Q 114 7.330 7.343 17.862 1.00110.44 C +ATOM 31354 OE1 GLN Q 114 6.765 8.384 18.193 1.00 85.39 O +ATOM 31355 NE2 GLN Q 114 7.727 7.103 16.610 1.00 97.60 N +ATOM 31356 N SER Q 115 10.934 5.916 20.460 1.00 88.27 N +ATOM 31357 CA SER Q 115 12.356 6.267 20.429 1.00 88.22 C +ATOM 31358 C SER Q 115 12.556 7.714 20.031 1.00 70.10 C +ATOM 31359 O SER Q 115 11.638 8.307 19.387 1.00 96.23 O +ATOM 31360 CB SER Q 115 13.064 5.375 19.424 1.00112.08 C +ATOM 31361 OG SER Q 115 12.380 5.366 18.158 1.00 54.42 O +ATOM 31362 N LEU Q 116 13.678 8.325 20.426 1.00 42.12 N +ATOM 31363 CA LEU Q 116 13.729 9.764 20.244 1.00 53.39 C +ATOM 31364 C LEU Q 116 13.928 10.028 18.782 1.00 57.18 C +ATOM 31365 O LEU Q 116 14.817 9.447 18.173 1.00 46.05 O +ATOM 31366 CB LEU Q 116 14.842 10.416 21.020 1.00 76.49 C +ATOM 31367 CG LEU Q 116 14.723 10.357 22.545 1.00103.95 C +ATOM 31368 CD1 LEU Q 116 15.476 9.165 23.116 1.00 94.74 C +ATOM 31369 CD2 LEU Q 116 15.258 11.677 23.098 1.00137.62 C +ATOM 31370 N THR Q 117 13.016 10.795 18.180 1.00 84.90 N +ATOM 31371 CA THR Q 117 13.078 11.096 16.755 1.00112.33 C +ATOM 31372 C THR Q 117 14.444 11.713 16.483 1.00125.89 C +ATOM 31373 O THR Q 117 14.867 12.611 17.206 1.00 93.52 O +ATOM 31374 CB THR Q 117 11.982 12.098 16.330 1.00135.05 C +ATOM 31375 OG1 THR Q 117 10.697 11.572 16.687 1.00100.39 O +ATOM 31376 CG2 THR Q 117 12.003 12.309 14.822 1.00167.27 C +ATOM 31377 N ALA Q 118 15.097 11.255 15.413 1.00126.66 N +ATOM 31378 CA ALA Q 118 16.498 11.585 15.161 1.00 94.34 C +ATOM 31379 C ALA Q 118 16.656 12.367 13.902 1.00 76.99 C +ATOM 31380 O ALA Q 118 16.018 12.059 12.868 1.00 64.18 O +ATOM 31381 CB ALA Q 118 17.330 10.326 15.078 1.00114.94 C +ATOM 31382 N ALA Q 119 17.535 13.353 13.984 1.00 66.38 N +ATOM 31383 CA ALA Q 119 17.737 14.297 12.889 1.00 83.22 C +ATOM 31384 C ALA Q 119 18.710 13.774 11.816 1.00 87.17 C +ATOM 31385 O ALA Q 119 19.568 12.947 12.114 1.00 67.46 O +ATOM 31386 CB ALA Q 119 18.244 15.597 13.451 1.00 79.67 C +ATOM 31387 N ASN Q 120 18.598 14.285 10.587 1.00 88.64 N +ATOM 31388 CA ASN Q 120 19.570 13.945 9.562 1.00 96.13 C +ATOM 31389 C ASN Q 120 20.640 15.011 9.403 1.00114.01 C +ATOM 31390 O ASN Q 120 21.827 14.717 9.236 1.00124.84 O +ATOM 31391 CB ASN Q 120 18.916 13.708 8.207 1.00107.66 C +ATOM 31392 CG ASN Q 120 19.936 13.272 7.153 1.00136.35 C +ATOM 31393 OD1 ASN Q 120 19.858 13.701 6.003 1.00173.35 O +ATOM 31394 ND2 ASN Q 120 20.934 12.451 7.551 1.00125.12 N +ATOM 31395 N ILE Q 121 20.211 16.263 9.326 1.00 98.12 N +ATOM 31396 CA ILE Q 121 21.164 17.357 9.278 1.00 67.11 C +ATOM 31397 C ILE Q 121 21.034 18.083 10.572 1.00 62.88 C +ATOM 31398 O ILE Q 121 19.958 18.221 11.118 1.00 46.31 O +ATOM 31399 CB ILE Q 121 20.950 18.312 8.080 1.00 60.02 C +ATOM 31400 CG1 ILE Q 121 19.707 19.202 8.266 1.00 60.68 C +ATOM 31401 CG2 ILE Q 121 20.878 17.528 6.757 1.00 59.37 C +ATOM 31402 CD1 ILE Q 121 20.013 20.670 8.494 1.00 52.63 C +ATOM 31403 N MET Q 122 22.160 18.508 11.106 1.00100.67 N +ATOM 31404 CA MET Q 122 22.114 19.442 12.206 1.00122.20 C +ATOM 31405 C MET Q 122 22.861 20.723 11.847 1.00111.69 C +ATOM 31406 O MET Q 122 23.796 20.706 11.068 1.00116.38 O +ATOM 31407 CB MET Q 122 22.670 18.794 13.468 1.00123.27 C +ATOM 31408 CG MET Q 122 24.094 18.285 13.360 1.00107.57 C +ATOM 31409 SD MET Q 122 24.867 18.314 14.967 1.00 80.92 S +ATOM 31410 CE MET Q 122 26.499 18.937 14.593 1.00 85.03 C +ATOM 31411 N VAL Q 123 22.325 21.846 12.288 1.00 87.25 N +ATOM 31412 CA VAL Q 123 22.880 23.131 11.936 1.00 79.62 C +ATOM 31413 C VAL Q 123 23.350 23.812 13.203 1.00 87.94 C +ATOM 31414 O VAL Q 123 22.592 24.008 14.132 1.00 84.31 O +ATOM 31415 CB VAL Q 123 21.879 24.043 11.203 1.00 82.73 C +ATOM 31416 CG1 VAL Q 123 20.488 23.941 11.804 1.00 94.26 C +ATOM 31417 CG2 VAL Q 123 22.353 25.502 11.215 1.00107.05 C +ATOM 31418 N GLU Q 124 24.602 24.235 13.196 1.00107.55 N +ATOM 31419 CA GLU Q 124 25.128 25.055 14.270 1.00111.37 C +ATOM 31420 C GLU Q 124 25.788 26.293 13.717 1.00114.44 C +ATOM 31421 O GLU Q 124 26.012 26.423 12.521 1.00117.99 O +ATOM 31422 CB GLU Q 124 26.126 24.271 15.125 1.00138.24 C +ATOM 31423 CG GLU Q 124 26.897 23.176 14.406 1.00140.13 C +ATOM 31424 CD GLU Q 124 27.518 22.185 15.381 1.00140.87 C +ATOM 31425 OE1 GLU Q 124 26.906 21.888 16.421 1.00100.40 O +ATOM 31426 OE2 GLU Q 124 28.625 21.715 15.097 1.00146.54 O +ATOM 31427 N GLY Q 125 26.122 27.208 14.609 1.00120.04 N +ATOM 31428 CA GLY Q 125 26.712 28.473 14.204 1.00109.66 C +ATOM 31429 C GLY Q 125 27.202 29.269 15.385 1.00104.69 C +ATOM 31430 O GLY Q 125 27.384 28.740 16.484 1.00105.40 O +ATOM 31431 N SER Q 126 27.373 30.564 15.177 1.00100.09 N +ATOM 31432 CA SER Q 126 27.948 31.402 16.212 1.00114.79 C +ATOM 31433 C SER Q 126 27.628 32.847 15.931 1.00105.12 C +ATOM 31434 O SER Q 126 27.493 33.248 14.782 1.00158.36 O +ATOM 31435 CB SER Q 126 29.470 31.250 16.249 1.00132.01 C +ATOM 31436 OG SER Q 126 29.901 29.950 15.852 1.00125.79 O +ATOM 31437 N ILE Q 127 27.487 33.639 16.978 1.00 83.76 N +ATOM 31438 CA ILE Q 127 27.464 35.068 16.798 1.00 64.64 C +ATOM 31439 C ILE Q 127 28.925 35.405 16.644 1.00 63.19 C +ATOM 31440 O ILE Q 127 29.637 35.578 17.617 1.00 69.22 O +ATOM 31441 CB ILE Q 127 26.769 35.844 17.943 1.00 57.40 C +ATOM 31442 CG1 ILE Q 127 25.251 35.525 17.987 1.00 56.22 C +ATOM 31443 CG2 ILE Q 127 26.967 37.354 17.796 1.00 46.39 C +ATOM 31444 CD1 ILE Q 127 24.661 35.570 19.397 1.00 62.20 C +ATOM 31445 N ILE Q 128 29.307 35.663 15.402 1.00 82.54 N +ATOM 31446 CA ILE Q 128 30.632 36.160 15.061 1.00113.91 C +ATOM 31447 C ILE Q 128 30.613 37.707 15.056 1.00119.75 C +ATOM 31448 O ILE Q 128 30.041 38.357 14.178 1.00177.68 O +ATOM 31449 CB ILE Q 128 31.060 35.577 13.708 1.00128.57 C +ATOM 31450 CG1 ILE Q 128 30.028 35.904 12.624 1.00131.41 C +ATOM 31451 CG2 ILE Q 128 31.109 34.057 13.800 1.00123.07 C +ATOM 31452 CD1 ILE Q 128 30.624 35.886 11.231 1.00182.74 C +ATOM 31453 N GLY Q 129 31.054 38.288 16.165 1.00 96.91 N +ATOM 31454 CA GLY Q 129 31.305 39.703 16.212 1.00101.18 C +ATOM 31455 C GLY Q 129 30.134 40.617 16.569 1.00115.61 C +ATOM 31456 O GLY Q 129 29.027 40.543 16.003 1.00142.14 O +ATOM 31457 N TYR Q 130 30.453 41.596 17.405 1.00125.47 N +ATOM 31458 CA TYR Q 130 29.662 42.824 17.548 1.00 99.38 C +ATOM 31459 C TYR Q 130 30.655 43.970 17.688 1.00101.70 C +ATOM 31460 O TYR Q 130 31.371 44.041 18.671 1.00156.84 O +ATOM 31461 CB TYR Q 130 28.780 42.715 18.785 1.00 69.90 C +ATOM 31462 CG TYR Q 130 28.000 43.942 19.143 1.00 71.63 C +ATOM 31463 CD1 TYR Q 130 28.630 45.089 19.594 1.00 80.46 C +ATOM 31464 CD2 TYR Q 130 26.606 43.921 19.128 1.00 97.03 C +ATOM 31465 CE1 TYR Q 130 27.893 46.215 19.954 1.00 99.55 C +ATOM 31466 CE2 TYR Q 130 25.858 45.034 19.496 1.00 99.87 C +ATOM 31467 CZ TYR Q 130 26.503 46.183 19.889 1.00 83.39 C +ATOM 31468 OH TYR Q 130 25.740 47.267 20.246 1.00 49.01 O +ATOM 31469 N GLU Q 131 30.806 44.773 16.645 1.00 98.37 N +ATOM 31470 CA GLU Q 131 31.573 45.995 16.757 1.00 89.26 C +ATOM 31471 C GLU Q 131 30.614 47.149 17.100 1.00 95.16 C +ATOM 31472 O GLU Q 131 29.457 47.154 16.664 1.00 64.01 O +ATOM 31473 CB GLU Q 131 32.321 46.230 15.458 1.00 97.56 C +ATOM 31474 CG GLU Q 131 33.349 47.350 15.496 1.00124.13 C +ATOM 31475 CD GLU Q 131 34.724 46.903 15.982 1.00138.11 C +ATOM 31476 OE1 GLU Q 131 35.082 45.722 15.786 1.00121.03 O +ATOM 31477 OE2 GLU Q 131 35.462 47.754 16.526 1.00150.89 O +ATOM 31478 N SER Q 132 31.101 48.128 17.857 1.00 97.08 N +ATOM 31479 CA SER Q 132 30.231 49.182 18.368 1.00106.98 C +ATOM 31480 C SER Q 132 30.657 50.583 17.883 1.00135.68 C +ATOM 31481 O SER Q 132 31.848 50.883 17.789 1.00145.86 O +ATOM 31482 CB SER Q 132 30.207 49.136 19.887 1.00102.01 C +ATOM 31483 OG SER Q 132 30.832 50.286 20.440 1.00133.91 O +ATOM 31484 N ASN Q 133 29.669 51.438 17.598 1.00134.73 N +ATOM 31485 CA ASN Q 133 29.896 52.729 16.917 1.00101.38 C +ATOM 31486 C ASN Q 133 30.787 52.568 15.701 1.00121.50 C +ATOM 31487 O ASN Q 133 31.849 53.189 15.595 1.00101.36 O +ATOM 31488 CB ASN Q 133 30.502 53.749 17.858 1.00 93.38 C +ATOM 31489 CG ASN Q 133 29.610 54.042 19.041 1.00130.39 C +ATOM 31490 OD1 ASN Q 133 28.378 53.913 18.978 1.00122.40 O +ATOM 31491 ND2 ASN Q 133 30.235 54.380 20.159 1.00159.77 N +ATOM 31492 N VAL Q 134 30.341 51.712 14.782 1.00146.86 N +ATOM 31493 CA VAL Q 134 31.068 51.435 13.549 1.00149.06 C +ATOM 31494 C VAL Q 134 30.994 52.696 12.695 1.00148.75 C +ATOM 31495 O VAL Q 134 31.966 53.066 12.026 1.00104.79 O +ATOM 31496 CB VAL Q 134 30.462 50.224 12.801 1.00117.64 C +ATOM 31497 CG1 VAL Q 134 31.279 49.902 11.561 1.00129.62 C +ATOM 31498 CG2 VAL Q 134 30.433 49.004 13.719 1.00157.04 C +ATOM 31499 N LYS Q 135 29.859 53.389 12.796 1.00143.28 N +ATOM 31500 CA LYS Q 135 29.764 54.777 12.343 1.00126.60 C +ATOM 31501 C LYS Q 135 28.973 55.648 13.304 1.00 94.63 C +ATOM 31502 O LYS Q 135 28.235 55.155 14.168 1.00 63.19 O +ATOM 31503 CB LYS Q 135 29.069 54.846 10.994 1.00189.93 C +ATOM 31504 CG LYS Q 135 29.806 54.117 9.884 1.00250.27 C +ATOM 31505 CD LYS Q 135 28.989 54.139 8.605 1.00252.12 C +ATOM 31506 CE LYS Q 135 29.692 53.404 7.483 1.00226.39 C +ATOM 31507 NZ LYS Q 135 29.160 53.841 6.170 1.00227.83 N +ATOM 31508 N SER Q 136 29.204 56.949 13.198 1.00107.12 N +ATOM 31509 CA SER Q 136 28.579 57.906 14.092 1.00129.89 C +ATOM 31510 C SER Q 136 28.689 59.315 13.549 1.00143.87 C +ATOM 31511 O SER Q 136 29.596 59.629 12.774 1.00119.27 O +ATOM 31512 CB SER Q 136 29.186 57.840 15.506 1.00157.97 C +ATOM 31513 OG SER Q 136 29.656 59.103 15.952 1.00179.04 O +ATOM 31514 N GLY Q 137 27.767 60.168 13.983 1.00156.63 N +ATOM 31515 CA GLY Q 137 27.787 61.571 13.584 1.00162.20 C +ATOM 31516 C GLY Q 137 26.852 62.452 14.397 1.00133.47 C +ATOM 31517 O GLY Q 137 26.122 61.975 15.254 1.00 82.35 O +ATOM 31518 N GLY Q 138 26.936 63.755 14.160 1.00123.03 N +ATOM 31519 CA GLY Q 138 26.094 64.704 14.855 1.00113.88 C +ATOM 31520 C GLY Q 138 26.039 66.035 14.147 1.00143.15 C +ATOM 31521 O GLY Q 138 27.031 66.484 13.554 1.00143.21 O +ATOM 31522 N VAL Q 139 24.867 66.665 14.192 1.00151.50 N +ATOM 31523 CA VAL Q 139 24.689 68.000 13.625 1.00138.28 C +ATOM 31524 C VAL Q 139 23.845 68.855 14.570 1.00119.90 C +ATOM 31525 O VAL Q 139 22.735 68.476 14.937 1.00 81.40 O +ATOM 31526 CB VAL Q 139 24.005 67.953 12.245 1.00121.15 C +ATOM 31527 CG1 VAL Q 139 23.725 69.361 11.758 1.00137.13 C +ATOM 31528 CG2 VAL Q 139 24.860 67.198 11.238 1.00104.51 C +ATOM 31529 N GLY Q 140 24.386 70.011 14.940 1.00115.63 N +ATOM 31530 CA GLY Q 140 23.718 70.903 15.863 1.00111.46 C +ATOM 31531 C GLY Q 140 24.041 72.365 15.625 1.00138.24 C +ATOM 31532 O GLY Q 140 25.154 72.733 15.229 1.00108.74 O +ATOM 31533 N ALA Q 141 23.053 73.214 15.870 1.00173.58 N +ATOM 31534 CA ALA Q 141 23.237 74.657 15.733 1.00179.12 C +ATOM 31535 C ALA Q 141 22.463 75.432 16.803 1.00193.01 C +ATOM 31536 O ALA Q 141 21.347 75.065 17.176 1.00163.69 O +ATOM 31537 CB ALA Q 141 22.836 75.116 14.339 1.00135.08 C +ATOM 31538 N ARG Q 142 23.092 76.475 17.326 1.00182.23 N +ATOM 31539 CA ARG Q 142 22.412 77.383 18.213 1.00168.03 C +ATOM 31540 C ARG Q 142 22.609 78.796 17.701 1.00198.04 C +ATOM 31541 O ARG Q 142 23.661 79.126 17.149 1.00212.41 O +ATOM 31542 CB ARG Q 142 22.918 77.244 19.649 1.00159.37 C +ATOM 31543 CG ARG Q 142 22.157 78.122 20.640 1.00179.81 C +ATOM 31544 CD ARG Q 142 21.840 77.418 21.951 1.00194.90 C +ATOM 31545 NE ARG Q 142 22.919 77.527 22.929 1.00205.94 N +ATOM 31546 CZ ARG Q 142 23.130 76.675 23.929 1.00203.47 C +ATOM 31547 NH1 ARG Q 142 22.367 75.596 24.066 1.00204.92 N +ATOM 31548 NH2 ARG Q 142 24.132 76.887 24.778 1.00182.62 N +ATOM 31549 N TYR Q 143 21.573 79.615 17.860 1.00215.83 N +ATOM 31550 CA TYR Q 143 21.546 80.962 17.303 1.00191.18 C +ATOM 31551 C TYR Q 143 21.129 81.988 18.365 1.00148.37 C +ATOM 31552 O TYR Q 143 19.959 82.378 18.466 1.00122.59 O +ATOM 31553 CB TYR Q 143 20.594 81.004 16.101 1.00194.47 C +ATOM 31554 CG TYR Q 143 20.616 82.318 15.383 1.00199.37 C +ATOM 31555 CD1 TYR Q 143 21.729 82.706 14.650 1.00189.07 C +ATOM 31556 CD2 TYR Q 143 19.551 83.203 15.488 1.00199.88 C +ATOM 31557 CE1 TYR Q 143 21.773 83.934 14.025 1.00200.78 C +ATOM 31558 CE2 TYR Q 143 19.580 84.436 14.866 1.00189.99 C +ATOM 31559 CZ TYR Q 143 20.696 84.797 14.138 1.00208.37 C +ATOM 31560 OH TYR Q 143 20.740 86.026 13.524 1.00256.38 O +ATOM 31561 N GLY Q 145 19.997 82.325 20.812 1.00140.10 N +ATOM 31562 CA GLY Q 145 19.173 81.891 21.928 1.00152.25 C +ATOM 31563 C GLY Q 145 18.502 80.538 21.718 1.00214.59 C +ATOM 31564 O GLY Q 145 18.176 79.863 22.694 1.00221.31 O +ATOM 31565 N ILE Q 146 18.299 80.132 20.460 1.00259.49 N +ATOM 31566 CA ILE Q 146 17.510 78.926 20.120 1.00235.27 C +ATOM 31567 C ILE Q 146 18.429 77.883 19.473 1.00232.31 C +ATOM 31568 O ILE Q 146 19.271 78.232 18.648 1.00193.86 O +ATOM 31569 CB ILE Q 146 16.340 79.251 19.146 1.00182.45 C +ATOM 31570 CG1 ILE Q 146 15.691 80.595 19.511 1.00185.48 C +ATOM 31571 CG2 ILE Q 146 15.299 78.141 19.163 1.00136.51 C +ATOM 31572 CD1 ILE Q 146 16.203 81.775 18.707 1.00163.36 C +ATOM 31573 N GLY Q 147 18.289 76.614 19.856 1.00214.63 N +ATOM 31574 CA GLY Q 147 19.197 75.583 19.353 1.00176.86 C +ATOM 31575 C GLY Q 147 18.620 74.187 19.239 1.00164.95 C +ATOM 31576 O GLY Q 147 17.667 73.827 19.917 1.00114.65 O +ATOM 31577 N ALA Q 148 19.193 73.406 18.335 1.00180.29 N +ATOM 31578 CA ALA Q 148 18.823 72.005 18.192 1.00172.18 C +ATOM 31579 C ALA Q 148 20.027 71.189 17.747 1.00174.16 C +ATOM 31580 O ALA Q 148 21.060 71.743 17.348 1.00138.66 O +ATOM 31581 CB ALA Q 148 17.671 71.845 17.208 1.00141.35 C +ATOM 31582 N ASP Q 149 19.901 69.873 17.861 1.00169.13 N +ATOM 31583 CA ASP Q 149 20.961 68.984 17.430 1.00159.10 C +ATOM 31584 C ASP Q 149 20.449 67.551 17.332 1.00136.15 C +ATOM 31585 O ASP Q 149 19.567 67.135 18.093 1.00 93.13 O +ATOM 31586 CB ASP Q 149 22.168 69.076 18.379 1.00181.14 C +ATOM 31587 CG ASP Q 149 21.985 68.269 19.633 1.00194.33 C +ATOM 31588 OD1 ASP Q 149 21.221 68.708 20.511 1.00172.77 O +ATOM 31589 OD2 ASP Q 149 22.616 67.203 19.748 1.00200.54 O +ATOM 31590 N THR Q 150 21.004 66.796 16.394 1.00129.76 N +ATOM 31591 CA THR Q 150 20.848 65.345 16.426 1.00137.74 C +ATOM 31592 C THR Q 150 22.211 64.678 16.457 1.00145.15 C +ATOM 31593 O THR Q 150 23.231 65.262 16.055 1.00 90.74 O +ATOM 31594 CB THR Q 150 20.072 64.796 15.216 1.00131.72 C +ATOM 31595 OG1 THR Q 150 20.763 65.156 14.009 1.00194.46 O +ATOM 31596 CG2 THR Q 150 18.672 65.330 15.195 1.00104.39 C +ATOM 31597 N GLN Q 151 22.216 63.455 16.968 1.00153.67 N +ATOM 31598 CA GLN Q 151 23.395 62.637 16.990 1.00171.44 C +ATOM 31599 C GLN Q 151 23.014 61.216 16.696 1.00145.00 C +ATOM 31600 O GLN Q 151 21.956 60.781 17.097 1.00 81.37 O +ATOM 31601 CB GLN Q 151 23.951 62.758 18.383 1.00198.31 C +ATOM 31602 CG GLN Q 151 25.309 62.184 18.683 1.00219.02 C +ATOM 31603 CD GLN Q 151 25.813 62.753 19.991 1.00197.52 C +ATOM 31604 OE1 GLN Q 151 25.017 63.003 20.895 1.00142.00 O +ATOM 31605 NE2 GLN Q 151 27.107 63.048 20.066 1.00193.13 N +ATOM 31606 N TYR Q 152 23.844 60.509 15.942 1.00142.76 N +ATOM 31607 CA TYR Q 152 23.538 59.130 15.620 1.00142.88 C +ATOM 31608 C TYR Q 152 24.744 58.234 15.739 1.00153.94 C +ATOM 31609 O TYR Q 152 25.882 58.670 15.499 1.00129.64 O +ATOM 31610 CB TYR Q 152 22.922 59.035 14.229 1.00139.17 C +ATOM 31611 CG TYR Q 152 23.817 58.525 13.115 1.00146.65 C +ATOM 31612 CD1 TYR Q 152 24.930 59.232 12.683 1.00141.42 C +ATOM 31613 CD2 TYR Q 152 23.486 57.365 12.437 1.00164.20 C +ATOM 31614 CE1 TYR Q 152 25.740 58.739 11.665 1.00151.13 C +ATOM 31615 CE2 TYR Q 152 24.247 56.897 11.371 1.00154.49 C +ATOM 31616 CZ TYR Q 152 25.385 57.578 10.996 1.00149.43 C +ATOM 31617 OH TYR Q 152 26.163 57.079 9.961 1.00132.16 O +ATOM 31618 N GLN Q 153 24.503 56.994 16.162 1.00139.27 N +ATOM 31619 CA GLN Q 153 25.553 55.984 16.137 1.00162.36 C +ATOM 31620 C GLN Q 153 25.006 54.672 15.595 1.00118.76 C +ATOM 31621 O GLN Q 153 23.807 54.427 15.658 1.00 65.41 O +ATOM 31622 CB GLN Q 153 26.125 55.777 17.542 1.00211.46 C +ATOM 31623 CG GLN Q 153 26.868 56.985 18.137 1.00222.56 C +ATOM 31624 CD GLN Q 153 27.305 56.725 19.590 1.00205.06 C +ATOM 31625 OE1 GLN Q 153 26.749 55.851 20.274 1.00240.15 O +ATOM 31626 NE2 GLN Q 153 28.281 57.492 20.069 1.00166.77 N +ATOM 31627 N LEU Q 154 25.885 53.865 15.002 1.00119.09 N +ATOM 31628 CA LEU Q 154 25.470 52.543 14.564 1.00137.96 C +ATOM 31629 C LEU Q 154 26.553 51.483 14.747 1.00181.09 C +ATOM 31630 O LEU Q 154 27.757 51.736 14.548 1.00161.43 O +ATOM 31631 CB LEU Q 154 24.991 52.566 13.112 1.00144.19 C +ATOM 31632 CG LEU Q 154 26.083 52.747 12.049 1.00193.41 C +ATOM 31633 CD1 LEU Q 154 26.560 51.411 11.501 1.00194.17 C +ATOM 31634 CD2 LEU Q 154 25.558 53.640 10.935 1.00249.99 C +ATOM 31635 N ASP Q 155 26.075 50.272 15.040 1.00195.06 N +ATOM 31636 CA ASP Q 155 26.897 49.132 15.469 1.00156.14 C +ATOM 31637 C ASP Q 155 26.715 47.986 14.466 1.00117.73 C +ATOM 31638 O ASP Q 155 25.717 47.963 13.744 1.00 72.91 O +ATOM 31639 CB ASP Q 155 26.472 48.687 16.884 1.00139.54 C +ATOM 31640 CG ASP Q 155 26.322 49.857 17.854 1.00167.05 C +ATOM 31641 OD1 ASP Q 155 25.288 50.567 17.794 1.00177.44 O +ATOM 31642 OD2 ASP Q 155 27.261 50.100 18.635 1.00160.03 O +ATOM 31643 N GLN Q 156 27.640 47.026 14.453 1.00118.12 N +ATOM 31644 CA GLN Q 156 27.528 45.841 13.584 1.00123.86 C +ATOM 31645 C GLN Q 156 27.375 44.517 14.368 1.00131.34 C +ATOM 31646 O GLN Q 156 27.699 44.436 15.545 1.00173.18 O +ATOM 31647 CB GLN Q 156 28.752 45.740 12.692 1.00 94.04 C +ATOM 31648 CG GLN Q 156 28.624 44.727 11.570 1.00121.78 C +ATOM 31649 CD GLN Q 156 29.679 44.916 10.488 1.00130.21 C +ATOM 31650 OE1 GLN Q 156 30.514 45.830 10.577 1.00127.37 O +ATOM 31651 NE2 GLN Q 156 29.528 44.179 9.382 1.00124.87 N +ATOM 31652 N ILE Q 157 26.767 43.524 13.732 1.00 90.43 N +ATOM 31653 CA ILE Q 157 26.580 42.237 14.330 1.00 62.09 C +ATOM 31654 C ILE Q 157 26.596 41.213 13.196 1.00 62.42 C +ATOM 31655 O ILE Q 157 26.002 41.438 12.126 1.00129.80 O +ATOM 31656 CB ILE Q 157 25.274 42.191 15.158 1.00 57.82 C +ATOM 31657 CG1 ILE Q 157 25.356 41.070 16.206 1.00110.36 C +ATOM 31658 CG2 ILE Q 157 24.073 41.929 14.285 1.00 61.53 C +ATOM 31659 CD1 ILE Q 157 24.205 41.043 17.200 1.00125.55 C +ATOM 31660 N ALA Q 158 27.258 40.088 13.394 1.00 65.30 N +ATOM 31661 CA ALA Q 158 27.342 39.074 12.341 1.00 93.26 C +ATOM 31662 C ALA Q 158 27.134 37.682 12.878 1.00 79.07 C +ATOM 31663 O ALA Q 158 27.308 37.434 14.056 1.00 90.38 O +ATOM 31664 CB ALA Q 158 28.679 39.133 11.628 1.00114.65 C +ATOM 31665 N VAL Q 159 26.651 36.805 12.006 1.00 72.90 N +ATOM 31666 CA VAL Q 159 26.194 35.503 12.433 1.00 64.88 C +ATOM 31667 C VAL Q 159 26.655 34.504 11.398 1.00 53.36 C +ATOM 31668 O VAL Q 159 26.299 34.613 10.223 1.00106.98 O +ATOM 31669 CB VAL Q 159 24.630 35.458 12.670 1.00 68.12 C +ATOM 31670 CG1 VAL Q 159 24.090 34.028 12.630 1.00 76.36 C +ATOM 31671 CG2 VAL Q 159 24.255 36.099 14.012 1.00 63.54 C +ATOM 31672 N ASN Q 160 27.279 33.453 11.873 1.00 41.24 N +ATOM 31673 CA ASN Q 160 27.498 32.280 11.090 1.00 43.44 C +ATOM 31674 C ASN Q 160 26.410 31.242 11.407 1.00 46.94 C +ATOM 31675 O ASN Q 160 26.112 30.922 12.577 1.00 29.70 O +ATOM 31676 CB ASN Q 160 28.878 31.705 11.391 1.00 55.21 C +ATOM 31677 CG ASN Q 160 29.260 30.555 10.428 1.00 61.49 C +ATOM 31678 OD1 ASN Q 160 30.058 30.720 9.491 1.00 43.01 O +ATOM 31679 ND2 ASN Q 160 28.676 29.386 10.647 1.00 78.90 N +ATOM 31680 N LEU Q 161 25.802 30.696 10.354 1.00 61.44 N +ATOM 31681 CA LEU Q 161 25.082 29.422 10.457 1.00 65.34 C +ATOM 31682 C LEU Q 161 25.694 28.397 9.494 1.00 55.61 C +ATOM 31683 O LEU Q 161 26.136 28.741 8.424 1.00 37.80 O +ATOM 31684 CB LEU Q 161 23.605 29.626 10.168 1.00 60.87 C +ATOM 31685 CG LEU Q 161 22.871 30.516 11.151 1.00 82.01 C +ATOM 31686 CD1 LEU Q 161 21.473 30.804 10.627 1.00139.62 C +ATOM 31687 CD2 LEU Q 161 22.804 29.848 12.514 1.00 74.84 C +ATOM 31688 N ARG Q 162 25.642 27.127 9.860 1.00 54.20 N +ATOM 31689 CA ARG Q 162 26.132 26.109 8.981 1.00 69.87 C +ATOM 31690 C ARG Q 162 25.458 24.728 9.137 1.00 70.71 C +ATOM 31691 O ARG Q 162 25.336 24.204 10.242 1.00115.75 O +ATOM 31692 CB ARG Q 162 27.657 26.022 9.096 1.00 80.64 C +ATOM 31693 CG ARG Q 162 28.235 25.583 10.439 1.00 89.10 C +ATOM 31694 CD ARG Q 162 29.702 25.141 10.264 1.00 82.07 C +ATOM 31695 NE ARG Q 162 30.314 24.508 11.429 1.00 62.74 N +ATOM 31696 CZ ARG Q 162 30.787 25.182 12.465 1.00 78.69 C +ATOM 31697 NH1 ARG Q 162 30.664 26.522 12.532 1.00104.27 N +ATOM 31698 NH2 ARG Q 162 31.349 24.526 13.466 1.00 79.61 N +ATOM 31699 N VAL Q 163 25.103 24.127 7.995 1.00 66.86 N +ATOM 31700 CA VAL Q 163 24.498 22.800 7.940 1.00 65.62 C +ATOM 31701 C VAL Q 163 25.554 21.734 7.894 1.00 55.07 C +ATOM 31702 O VAL Q 163 26.378 21.724 6.982 1.00 60.10 O +ATOM 31703 CB VAL Q 163 23.673 22.606 6.670 1.00 80.54 C +ATOM 31704 CG1 VAL Q 163 23.091 21.192 6.644 1.00 89.31 C +ATOM 31705 CG2 VAL Q 163 22.583 23.685 6.569 1.00 96.05 C +ATOM 31706 N VAL Q 164 25.493 20.829 8.864 1.00 42.38 N +ATOM 31707 CA VAL Q 164 26.419 19.736 8.977 1.00 46.72 C +ATOM 31708 C VAL Q 164 25.712 18.435 8.771 1.00 41.96 C +ATOM 31709 O VAL Q 164 24.611 18.244 9.269 1.00 39.63 O +ATOM 31710 CB VAL Q 164 27.040 19.658 10.356 1.00 64.26 C +ATOM 31711 CG1 VAL Q 164 27.986 18.456 10.444 1.00 95.21 C +ATOM 31712 CG2 VAL Q 164 27.807 20.928 10.653 1.00 76.07 C +ATOM 31713 N ASN Q 165 26.327 17.565 7.975 1.00 45.72 N +ATOM 31714 CA ASN Q 165 25.711 16.295 7.636 1.00 69.49 C +ATOM 31715 C ASN Q 165 26.072 15.270 8.686 1.00 88.31 C +ATOM 31716 O ASN Q 165 27.243 14.961 8.859 1.00 85.09 O +ATOM 31717 CB ASN Q 165 26.147 15.786 6.250 1.00 81.91 C +ATOM 31718 CG ASN Q 165 25.334 14.578 5.792 1.00 93.15 C +ATOM 31719 OD1 ASN Q 165 24.359 14.199 6.444 1.00 88.75 O +ATOM 31720 ND2 ASN Q 165 25.788 13.920 4.738 1.00 94.48 N +ATOM 31721 N VAL Q 166 25.046 14.742 9.361 1.00109.34 N +ATOM 31722 CA VAL Q 166 25.224 13.808 10.457 1.00 87.11 C +ATOM 31723 C VAL Q 166 25.895 12.562 9.970 1.00 64.84 C +ATOM 31724 O VAL Q 166 26.793 12.048 10.630 1.00105.84 O +ATOM 31725 CB VAL Q 166 23.876 13.424 11.088 1.00 90.66 C +ATOM 31726 CG1 VAL Q 166 23.959 12.061 11.778 1.00 87.35 C +ATOM 31727 CG2 VAL Q 166 23.412 14.533 12.044 1.00 98.19 C +ATOM 31728 N SER Q 167 25.537 12.152 8.776 1.00 53.21 N +ATOM 31729 CA SER Q 167 26.033 10.923 8.255 1.00 73.99 C +ATOM 31730 C SER Q 167 27.534 10.955 7.892 1.00 63.10 C +ATOM 31731 O SER Q 167 28.119 9.865 7.643 1.00 98.12 O +ATOM 31732 CB SER Q 167 25.184 10.508 7.044 1.00103.52 C +ATOM 31733 OG SER Q 167 23.803 10.696 7.319 1.00110.77 O +ATOM 31734 N THR Q 168 28.138 12.142 7.813 1.00 40.62 N +ATOM 31735 CA THR Q 168 29.532 12.240 7.373 1.00 52.48 C +ATOM 31736 C THR Q 168 30.379 13.240 8.119 1.00 61.15 C +ATOM 31737 O THR Q 168 31.581 13.037 8.370 1.00 92.94 O +ATOM 31738 CB THR Q 168 29.643 12.650 5.902 1.00 58.81 C +ATOM 31739 OG1 THR Q 168 28.845 13.802 5.675 1.00 72.61 O +ATOM 31740 CG2 THR Q 168 29.180 11.513 4.972 1.00 67.97 C +ATOM 31741 N GLY Q 169 29.757 14.314 8.536 1.00 70.63 N +ATOM 31742 CA GLY Q 169 30.506 15.338 9.230 1.00 78.25 C +ATOM 31743 C GLY Q 169 30.912 16.383 8.242 1.00103.86 C +ATOM 31744 O GLY Q 169 31.351 17.468 8.638 1.00176.99 O +ATOM 31745 N GLU Q 170 30.739 16.096 6.948 1.00111.52 N +ATOM 31746 CA GLU Q 170 30.839 17.148 5.913 1.00145.18 C +ATOM 31747 C GLU Q 170 29.905 18.315 6.272 1.00107.81 C +ATOM 31748 O GLU Q 170 28.745 18.106 6.575 1.00127.88 O +ATOM 31749 CB GLU Q 170 30.464 16.620 4.514 1.00145.55 C +ATOM 31750 CG GLU Q 170 31.535 15.754 3.866 1.00127.59 C +ATOM 31751 CD GLU Q 170 30.982 14.604 3.047 1.00148.38 C +ATOM 31752 OE1 GLU Q 170 29.762 14.326 3.133 1.00194.48 O +ATOM 31753 OE2 GLU Q 170 31.774 13.930 2.356 1.00163.87 O +ATOM 31754 N ILE Q 171 30.439 19.518 6.334 1.00 58.79 N +ATOM 31755 CA ILE Q 171 29.601 20.643 6.371 1.00 53.75 C +ATOM 31756 C ILE Q 171 28.970 20.758 4.999 1.00 69.60 C +ATOM 31757 O ILE Q 171 29.679 20.826 3.981 1.00107.18 O +ATOM 31758 CB ILE Q 171 30.411 21.874 6.719 1.00 66.40 C +ATOM 31759 CG1 ILE Q 171 30.826 21.808 8.187 1.00 68.10 C +ATOM 31760 CG2 ILE Q 171 29.603 23.140 6.435 1.00 70.34 C +ATOM 31761 CD1 ILE Q 171 31.933 22.772 8.537 1.00 81.16 C +ATOM 31762 N LEU Q 172 27.640 20.848 4.948 1.00 89.91 N +ATOM 31763 CA LEU Q 172 26.919 20.952 3.663 1.00 97.88 C +ATOM 31764 C LEU Q 172 26.592 22.399 3.221 1.00103.28 C +ATOM 31765 O LEU Q 172 26.296 22.693 2.034 1.00 56.88 O +ATOM 31766 CB LEU Q 172 25.622 20.175 3.708 1.00 84.54 C +ATOM 31767 CG LEU Q 172 25.844 18.645 3.774 1.00128.38 C +ATOM 31768 CD1 LEU Q 172 24.567 17.785 3.676 1.00166.35 C +ATOM 31769 CD2 LEU Q 172 26.928 18.120 2.830 1.00105.62 C +ATOM 31770 N SER Q 173 26.774 23.325 4.154 1.00133.11 N +ATOM 31771 CA SER Q 173 26.630 24.747 3.837 1.00138.06 C +ATOM 31772 C SER Q 173 27.127 25.629 4.972 1.00119.03 C +ATOM 31773 O SER Q 173 26.772 25.397 6.133 1.00206.42 O +ATOM 31774 CB SER Q 173 25.160 25.043 3.590 1.00155.57 C +ATOM 31775 OG SER Q 173 24.914 26.423 3.639 1.00130.59 O +ATOM 31776 N SER Q 174 27.918 26.645 4.648 1.00 71.18 N +ATOM 31777 CA SER Q 174 28.217 27.676 5.619 1.00 86.24 C +ATOM 31778 C SER Q 174 27.710 29.009 5.071 1.00 89.71 C +ATOM 31779 O SER Q 174 27.965 29.333 3.917 1.00116.26 O +ATOM 31780 CB SER Q 174 29.732 27.719 5.923 1.00 78.43 C +ATOM 31781 OG SER Q 174 30.035 28.557 7.051 1.00102.84 O +ATOM 31782 N VAL Q 175 27.074 29.817 5.924 1.00 69.46 N +ATOM 31783 CA VAL Q 175 26.667 31.168 5.542 1.00 57.15 C +ATOM 31784 C VAL Q 175 27.003 32.219 6.613 1.00 81.55 C +ATOM 31785 O VAL Q 175 26.929 31.958 7.812 1.00 97.22 O +ATOM 31786 CB VAL Q 175 25.167 31.211 5.270 1.00 59.64 C +ATOM 31787 CG1 VAL Q 175 24.834 30.303 4.096 1.00 89.62 C +ATOM 31788 CG2 VAL Q 175 24.370 30.776 6.479 1.00 54.07 C +ATOM 31789 N ASN Q 176 27.292 33.442 6.166 1.00106.18 N +ATOM 31790 CA ASN Q 176 27.768 34.526 7.043 1.00104.53 C +ATOM 31791 C ASN Q 176 26.951 35.815 6.893 1.00 76.75 C +ATOM 31792 O ASN Q 176 27.260 36.623 6.034 1.00 90.87 O +ATOM 31793 CB ASN Q 176 29.253 34.806 6.700 1.00129.47 C +ATOM 31794 CG ASN Q 176 30.245 34.091 7.629 1.00136.12 C +ATOM 31795 OD1 ASN Q 176 31.479 34.398 7.680 1.00 71.80 O +ATOM 31796 ND2 ASN Q 176 29.703 33.169 8.413 1.00135.52 N +ATOM 31797 N THR Q 177 25.941 36.014 7.730 1.00 65.33 N +ATOM 31798 CA THR Q 177 25.064 37.175 7.617 1.00102.12 C +ATOM 31799 C THR Q 177 25.475 38.300 8.579 1.00107.82 C +ATOM 31800 O THR Q 177 26.191 38.058 9.531 1.00104.94 O +ATOM 31801 CB THR Q 177 23.583 36.816 7.869 1.00108.70 C +ATOM 31802 OG1 THR Q 177 23.399 36.505 9.253 1.00136.99 O +ATOM 31803 CG2 THR Q 177 23.143 35.624 7.012 1.00 98.95 C +ATOM 31804 N SER Q 178 25.011 39.524 8.305 1.00163.28 N +ATOM 31805 CA SER Q 178 25.407 40.727 9.061 1.00160.39 C +ATOM 31806 C SER Q 178 24.287 41.766 9.093 1.00130.10 C +ATOM 31807 O SER Q 178 23.450 41.821 8.210 1.00168.52 O +ATOM 31808 CB SER Q 178 26.667 41.386 8.462 1.00148.85 C +ATOM 31809 OG SER Q 178 26.874 42.690 9.004 1.00103.51 O +ATOM 31810 N LYS Q 179 24.318 42.627 10.093 1.00100.07 N +ATOM 31811 CA LYS Q 179 23.211 43.517 10.334 1.00115.80 C +ATOM 31812 C LYS Q 179 23.674 44.693 11.181 1.00117.38 C +ATOM 31813 O LYS Q 179 24.492 44.551 12.103 1.00163.49 O +ATOM 31814 CB LYS Q 179 22.056 42.757 11.023 1.00147.72 C +ATOM 31815 CG LYS Q 179 20.667 43.197 10.597 1.00139.94 C +ATOM 31816 CD LYS Q 179 20.124 44.245 11.551 1.00148.81 C +ATOM 31817 CE LYS Q 179 18.823 44.817 11.032 1.00175.31 C +ATOM 31818 NZ LYS Q 179 18.428 46.041 11.773 1.00206.50 N +ATOM 31819 N THR Q 180 23.088 45.844 10.909 1.00129.83 N +ATOM 31820 CA THR Q 180 23.482 47.072 11.563 1.00157.49 C +ATOM 31821 C THR Q 180 22.421 47.543 12.572 1.00139.20 C +ATOM 31822 O THR Q 180 21.227 47.608 12.265 1.00112.30 O +ATOM 31823 CB THR Q 180 23.795 48.190 10.536 1.00198.53 C +ATOM 31824 OG1 THR Q 180 23.621 49.476 11.153 1.00222.58 O +ATOM 31825 CG2 THR Q 180 22.894 48.088 9.315 1.00205.62 C +ATOM 31826 N ILE Q 181 22.883 47.907 13.767 1.00149.80 N +ATOM 31827 CA ILE Q 181 22.007 48.440 14.820 1.00149.21 C +ATOM 31828 C ILE Q 181 22.062 49.981 14.890 1.00163.76 C +ATOM 31829 O ILE Q 181 23.117 50.554 15.159 1.00117.73 O +ATOM 31830 CB ILE Q 181 22.369 47.837 16.202 1.00127.93 C +ATOM 31831 CG1 ILE Q 181 22.414 46.312 16.114 1.00118.00 C +ATOM 31832 CG2 ILE Q 181 21.371 48.252 17.271 1.00111.42 C +ATOM 31833 CD1 ILE Q 181 23.767 45.741 16.443 1.00147.54 C +ATOM 31834 N LEU Q 182 20.915 50.635 14.648 1.00172.20 N +ATOM 31835 CA LEU Q 182 20.801 52.109 14.623 1.00152.53 C +ATOM 31836 C LEU Q 182 20.407 52.742 15.970 1.00116.36 C +ATOM 31837 O LEU Q 182 19.496 52.269 16.644 1.00 61.16 O +ATOM 31838 CB LEU Q 182 19.781 52.548 13.563 1.00152.79 C +ATOM 31839 CG LEU Q 182 19.557 54.058 13.433 1.00158.64 C +ATOM 31840 CD1 LEU Q 182 20.828 54.799 13.010 1.00155.64 C +ATOM 31841 CD2 LEU Q 182 18.416 54.299 12.461 1.00159.38 C +ATOM 31842 N SER Q 183 21.076 53.846 16.302 1.00127.87 N +ATOM 31843 CA SER Q 183 20.726 54.655 17.460 1.00126.77 C +ATOM 31844 C SER Q 183 20.811 56.152 17.122 1.00168.23 C +ATOM 31845 O SER Q 183 21.697 56.581 16.378 1.00128.90 O +ATOM 31846 CB SER Q 183 21.673 54.344 18.599 1.00115.60 C +ATOM 31847 OG SER Q 183 21.994 52.967 18.631 1.00149.21 O +ATOM 31848 N TYR Q 184 19.868 56.940 17.648 1.00181.46 N +ATOM 31849 CA TYR Q 184 19.889 58.395 17.448 1.00128.84 C +ATOM 31850 C TYR Q 184 19.254 59.204 18.595 1.00116.67 C +ATOM 31851 O TYR Q 184 18.390 58.716 19.341 1.00 74.62 O +ATOM 31852 CB TYR Q 184 19.271 58.766 16.102 1.00 87.91 C +ATOM 31853 CG TYR Q 184 17.846 58.328 15.950 1.00116.36 C +ATOM 31854 CD1 TYR Q 184 16.788 59.109 16.445 1.00150.95 C +ATOM 31855 CD2 TYR Q 184 17.534 57.156 15.286 1.00137.88 C +ATOM 31856 CE1 TYR Q 184 15.470 58.712 16.306 1.00135.54 C +ATOM 31857 CE2 TYR Q 184 16.220 56.749 15.137 1.00156.98 C +ATOM 31858 CZ TYR Q 184 15.194 57.535 15.641 1.00154.62 C +ATOM 31859 OH TYR Q 184 13.897 57.111 15.515 1.00179.78 O +ATOM 31860 N GLU Q 185 19.734 60.440 18.725 1.00127.05 N +ATOM 31861 CA GLU Q 185 19.310 61.367 19.766 1.00167.04 C +ATOM 31862 C GLU Q 185 18.994 62.732 19.169 1.00190.59 C +ATOM 31863 O GLU Q 185 19.884 63.445 18.718 1.00154.46 O +ATOM 31864 CB GLU Q 185 20.371 61.554 20.853 1.00186.13 C +ATOM 31865 CG GLU Q 185 21.088 60.302 21.304 1.00205.47 C +ATOM 31866 CD GLU Q 185 21.960 60.572 22.518 1.00215.04 C +ATOM 31867 OE1 GLU Q 185 22.029 61.743 22.964 1.00216.77 O +ATOM 31868 OE2 GLU Q 185 22.552 59.612 23.045 1.00207.49 O +ATOM 31869 N VAL Q 186 17.721 63.101 19.215 1.00202.25 N +ATOM 31870 CA VAL Q 186 17.265 64.410 18.768 1.00178.83 C +ATOM 31871 C VAL Q 186 17.011 65.324 19.974 1.00160.05 C +ATOM 31872 O VAL Q 186 16.458 64.877 20.981 1.00123.67 O +ATOM 31873 CB VAL Q 186 15.983 64.274 17.925 1.00161.15 C +ATOM 31874 CG1 VAL Q 186 15.623 65.606 17.290 1.00165.83 C +ATOM 31875 CG2 VAL Q 186 16.154 63.204 16.859 1.00142.53 C +ATOM 31876 N GLN Q 187 17.419 66.591 19.866 1.00133.17 N +ATOM 31877 CA GLN Q 187 17.299 67.524 20.979 1.00134.78 C +ATOM 31878 C GLN Q 187 17.076 68.944 20.501 1.00147.91 C +ATOM 31879 O GLN Q 187 17.715 69.390 19.550 1.00101.83 O +ATOM 31880 CB GLN Q 187 18.581 67.489 21.811 1.00152.34 C +ATOM 31881 CG GLN Q 187 18.641 66.413 22.878 1.00176.83 C +ATOM 31882 CD GLN Q 187 20.062 66.114 23.317 1.00180.33 C +ATOM 31883 OE1 GLN Q 187 20.892 67.023 23.416 1.00151.47 O +ATOM 31884 NE2 GLN Q 187 20.363 64.830 23.553 1.00173.16 N +ATOM 31885 N ALA Q 188 16.200 69.668 21.194 1.00173.53 N +ATOM 31886 CA ALA Q 188 15.975 71.087 20.903 1.00171.86 C +ATOM 31887 C ALA Q 188 15.775 71.884 22.190 1.00180.35 C +ATOM 31888 O ALA Q 188 15.147 71.398 23.118 1.00163.13 O +ATOM 31889 CB ALA Q 188 14.782 71.249 19.974 1.00136.30 C +ATOM 31890 N GLY Q 189 16.340 73.088 22.253 1.00174.95 N +ATOM 31891 CA GLY Q 189 16.239 73.933 23.434 1.00168.90 C +ATOM 31892 C GLY Q 189 16.145 75.409 23.116 1.00182.89 C +ATOM 31893 O GLY Q 189 16.811 75.899 22.208 1.00149.09 O +ATOM 31894 N VAL Q 190 15.266 76.108 23.826 1.00217.76 N +ATOM 31895 CA VAL Q 190 15.071 77.543 23.628 1.00229.97 C +ATOM 31896 C VAL Q 190 15.489 78.297 24.897 1.00225.78 C +ATOM 31897 O VAL Q 190 15.164 77.882 26.008 1.00184.47 O +ATOM 31898 CB VAL Q 190 13.601 77.877 23.281 1.00206.53 C +ATOM 31899 CG1 VAL Q 190 13.480 79.327 22.839 1.00194.48 C +ATOM 31900 CG2 VAL Q 190 13.062 76.936 22.204 1.00177.21 C +ATOM 31901 N PHE Q 191 16.229 79.390 24.726 1.00230.85 N +ATOM 31902 CA PHE Q 191 16.857 80.078 25.855 1.00221.72 C +ATOM 31903 C PHE Q 191 16.622 81.583 25.752 1.00183.09 C +ATOM 31904 O PHE Q 191 16.872 82.173 24.695 1.00185.73 O +ATOM 31905 CB PHE Q 191 18.365 79.754 25.894 1.00232.11 C +ATOM 31906 CG PHE Q 191 19.007 79.975 27.239 1.00243.08 C +ATOM 31907 CD1 PHE Q 191 19.245 81.258 27.711 1.00204.57 C +ATOM 31908 CD2 PHE Q 191 19.402 78.896 28.023 1.00253.34 C +ATOM 31909 CE1 PHE Q 191 19.845 81.464 28.943 1.00178.24 C +ATOM 31910 CE2 PHE Q 191 19.992 79.095 29.260 1.00221.79 C +ATOM 31911 CZ PHE Q 191 20.217 80.382 29.720 1.00188.91 C +ATOM 31912 N LEU Q 200 13.823 82.732 30.563 1.00290.01 N +ATOM 31913 CA LEU Q 200 13.146 81.636 29.873 1.00290.82 C +ATOM 31914 C LEU Q 200 14.136 80.607 29.342 1.00273.50 C +ATOM 31915 O LEU Q 200 14.919 80.902 28.432 1.00222.63 O +ATOM 31916 CB LEU Q 200 12.309 82.164 28.701 1.00265.76 C +ATOM 31917 CG LEU Q 200 11.728 81.064 27.790 1.00212.11 C +ATOM 31918 CD1 LEU Q 200 10.261 80.832 28.125 1.00195.95 C +ATOM 31919 CD2 LEU Q 200 11.921 81.356 26.305 1.00165.33 C +ATOM 31920 N GLU Q 201 14.074 79.399 29.898 1.00238.71 N +ATOM 31921 CA GLU Q 201 14.650 78.227 29.256 1.00200.15 C +ATOM 31922 C GLU Q 201 13.575 77.180 29.001 1.00166.07 C +ATOM 31923 O GLU Q 201 12.620 77.065 29.765 1.00 95.15 O +ATOM 31924 CB GLU Q 201 15.760 77.626 30.116 1.00219.06 C +ATOM 31925 CG GLU Q 201 16.700 76.725 29.328 1.00227.10 C +ATOM 31926 CD GLU Q 201 17.817 76.133 30.178 1.00226.50 C +ATOM 31927 OE1 GLU Q 201 18.501 76.891 30.896 1.00226.64 O +ATOM 31928 OE2 GLU Q 201 18.023 74.906 30.118 1.00205.11 O +ATOM 31929 N GLY Q 202 13.736 76.421 27.920 1.00172.34 N +ATOM 31930 CA GLY Q 202 12.859 75.290 27.626 1.00162.23 C +ATOM 31931 C GLY Q 202 13.562 74.256 26.758 1.00146.99 C +ATOM 31932 O GLY Q 202 14.087 74.586 25.700 1.00109.69 O +ATOM 31933 N GLU Q 203 13.527 72.993 27.177 1.00135.94 N +ATOM 31934 CA GLU Q 203 14.178 71.917 26.422 1.00145.01 C +ATOM 31935 C GLU Q 203 13.264 70.719 26.134 1.00137.03 C +ATOM 31936 O GLU Q 203 12.521 70.259 27.005 1.00 91.40 O +ATOM 31937 CB GLU Q 203 15.442 71.445 27.155 1.00167.01 C +ATOM 31938 CG GLU Q 203 16.512 72.527 27.207 1.00160.89 C +ATOM 31939 CD GLU Q 203 17.439 72.595 26.000 1.00163.17 C +ATOM 31940 OE1 GLU Q 203 17.841 71.560 25.443 1.00152.46 O +ATOM 31941 OE2 GLU Q 203 17.833 73.707 25.623 1.00165.89 O +ATOM 31942 N VAL Q 204 13.364 70.204 24.907 1.00166.60 N +ATOM 31943 CA VAL Q 204 12.763 68.930 24.510 1.00184.94 C +ATOM 31944 C VAL Q 204 13.856 67.990 23.976 1.00202.79 C +ATOM 31945 O VAL Q 204 14.732 68.408 23.217 1.00171.85 O +ATOM 31946 CB VAL Q 204 11.663 69.144 23.441 1.00144.69 C +ATOM 31947 CG1 VAL Q 204 11.284 67.836 22.746 1.00140.73 C +ATOM 31948 CG2 VAL Q 204 10.439 69.782 24.079 1.00106.81 C +ATOM 31949 N GLY Q 205 13.794 66.723 24.389 1.00180.33 N +ATOM 31950 CA GLY Q 205 14.721 65.708 23.910 1.00143.68 C +ATOM 31951 C GLY Q 205 14.042 64.385 23.597 1.00155.40 C +ATOM 31952 O GLY Q 205 13.014 64.051 24.188 1.00133.86 O +ATOM 31953 N TYR Q 206 14.625 63.620 22.672 1.00199.98 N +ATOM 31954 CA TYR Q 206 14.168 62.254 22.351 1.00222.00 C +ATOM 31955 C TYR Q 206 15.351 61.379 21.919 1.00202.51 C +ATOM 31956 O TYR Q 206 16.225 61.848 21.210 1.00145.36 O +ATOM 31957 CB TYR Q 206 13.117 62.287 21.227 1.00209.18 C +ATOM 31958 CG TYR Q 206 12.620 60.925 20.780 1.00190.62 C +ATOM 31959 CD1 TYR Q 206 11.699 60.209 21.548 1.00152.27 C +ATOM 31960 CD2 TYR Q 206 13.072 60.358 19.586 1.00185.35 C +ATOM 31961 CE1 TYR Q 206 11.258 58.964 21.147 1.00148.90 C +ATOM 31962 CE2 TYR Q 206 12.633 59.115 19.171 1.00180.68 C +ATOM 31963 CZ TYR Q 206 11.732 58.419 19.955 1.00189.36 C +ATOM 31964 OH TYR Q 206 11.340 57.157 19.552 1.00243.83 O +ATOM 31965 N THR Q 207 15.359 60.110 22.332 1.00178.20 N +ATOM 31966 CA THR Q 207 16.417 59.169 21.932 1.00147.68 C +ATOM 31967 C THR Q 207 15.861 57.778 21.592 1.00146.33 C +ATOM 31968 O THR Q 207 14.949 57.282 22.267 1.00127.51 O +ATOM 31969 CB THR Q 207 17.452 58.993 23.044 1.00148.30 C +ATOM 31970 OG1 THR Q 207 16.812 58.446 24.205 1.00142.28 O +ATOM 31971 CG2 THR Q 207 18.082 60.319 23.410 1.00149.23 C +ATOM 31972 N SER Q 208 16.365 57.171 20.513 1.00155.32 N +ATOM 31973 CA SER Q 208 15.861 55.849 20.079 1.00140.05 C +ATOM 31974 C SER Q 208 16.977 54.886 19.693 1.00162.50 C +ATOM 31975 O SER Q 208 17.839 55.216 18.862 1.00160.13 O +ATOM 31976 CB SER Q 208 14.893 55.978 18.904 1.00135.35 C +ATOM 31977 OG SER Q 208 14.515 54.700 18.410 1.00 90.77 O +ATOM 31978 N ASN Q 209 16.940 53.700 20.295 1.00154.48 N +ATOM 31979 CA ASN Q 209 17.880 52.634 19.980 1.00151.08 C +ATOM 31980 C ASN Q 209 17.159 51.460 19.367 1.00155.12 C +ATOM 31981 O ASN Q 209 16.098 51.078 19.839 1.00122.80 O +ATOM 31982 CB ASN Q 209 18.574 52.146 21.240 1.00140.90 C +ATOM 31983 CG ASN Q 209 19.536 53.164 21.794 1.00145.18 C +ATOM 31984 OD1 ASN Q 209 20.686 53.246 21.368 1.00159.53 O +ATOM 31985 ND2 ASN Q 209 19.094 53.896 22.799 1.00156.81 N +ATOM 31986 N GLU Q 210 17.750 50.872 18.326 1.00162.94 N +ATOM 31987 CA GLU Q 210 17.276 49.586 17.818 1.00114.92 C +ATOM 31988 C GLU Q 210 17.587 48.547 18.870 1.00109.42 C +ATOM 31989 O GLU Q 210 18.634 48.605 19.530 1.00110.79 O +ATOM 31990 CB GLU Q 210 17.968 49.215 16.506 1.00115.23 C +ATOM 31991 CG GLU Q 210 17.054 48.645 15.433 1.00111.56 C +ATOM 31992 CD GLU Q 210 17.686 48.688 14.038 1.00141.76 C +ATOM 31993 OE1 GLU Q 210 18.578 49.551 13.752 1.00110.04 O +ATOM 31994 OE2 GLU Q 210 17.313 47.826 13.209 1.00176.09 O +ATOM 31995 N PRO Q 211 16.680 47.599 19.051 1.00115.35 N +ATOM 31996 CA PRO Q 211 16.999 46.494 19.927 1.00140.22 C +ATOM 31997 C PRO Q 211 18.021 45.533 19.274 1.00167.68 C +ATOM 31998 O PRO Q 211 17.794 45.046 18.163 1.00155.32 O +ATOM 31999 CB PRO Q 211 15.642 45.811 20.138 1.00132.09 C +ATOM 32000 CG PRO Q 211 14.623 46.812 19.744 1.00133.60 C +ATOM 32001 CD PRO Q 211 15.271 47.595 18.647 1.00133.93 C +ATOM 32002 N VAL Q 212 19.131 45.274 19.973 1.00136.04 N +ATOM 32003 CA VAL Q 212 20.174 44.343 19.505 1.00 81.13 C +ATOM 32004 C VAL Q 212 19.606 42.935 19.433 1.00 57.36 C +ATOM 32005 O VAL Q 212 19.804 42.209 18.467 1.00 35.12 O +ATOM 32006 CB VAL Q 212 21.366 44.314 20.469 1.00115.69 C +ATOM 32007 CG1 VAL Q 212 22.480 43.453 19.900 1.00114.84 C +ATOM 32008 CG2 VAL Q 212 21.873 45.726 20.773 1.00165.31 C +ATOM 32009 N MET Q 213 18.832 42.606 20.453 1.00 55.01 N +ATOM 32010 CA MET Q 213 17.856 41.518 20.431 1.00 88.93 C +ATOM 32011 C MET Q 213 17.192 41.251 19.054 1.00113.32 C +ATOM 32012 O MET Q 213 17.173 40.117 18.543 1.00150.65 O +ATOM 32013 CB MET Q 213 16.784 41.899 21.465 1.00 91.96 C +ATOM 32014 CG MET Q 213 15.714 40.884 21.776 1.00 92.79 C +ATOM 32015 SD MET Q 213 14.653 41.609 23.014 1.00125.31 S +ATOM 32016 CE MET Q 213 13.221 41.902 22.016 1.00149.06 C +ATOM 32017 N LEU Q 214 16.651 42.312 18.464 1.00138.00 N +ATOM 32018 CA LEU Q 214 15.734 42.216 17.323 1.00128.90 C +ATOM 32019 C LEU Q 214 16.524 42.169 16.026 1.00118.68 C +ATOM 32020 O LEU Q 214 16.130 41.492 15.074 1.00120.91 O +ATOM 32021 CB LEU Q 214 14.794 43.425 17.297 1.00119.35 C +ATOM 32022 CG LEU Q 214 13.310 43.184 16.982 1.00138.32 C +ATOM 32023 CD1 LEU Q 214 12.619 42.232 17.984 1.00149.90 C +ATOM 32024 CD2 LEU Q 214 12.603 44.539 16.934 1.00139.23 C +ATOM 32025 N CYS Q 215 17.702 42.768 16.056 1.00120.44 N +ATOM 32026 CA CYS Q 215 18.643 42.655 14.949 1.00141.36 C +ATOM 32027 C CYS Q 215 19.273 41.259 14.844 1.00124.41 C +ATOM 32028 O CYS Q 215 19.445 40.701 13.733 1.00114.39 O +ATOM 32029 CB CYS Q 215 19.760 43.665 15.139 1.00186.60 C +ATOM 32030 SG CYS Q 215 19.176 45.362 15.136 1.00245.85 S +ATOM 32031 N LEU Q 216 19.647 40.705 16.001 1.00 89.22 N +ATOM 32032 CA LEU Q 216 20.110 39.331 16.060 1.00 79.63 C +ATOM 32033 C LEU Q 216 19.065 38.375 15.445 1.00 97.22 C +ATOM 32034 O LEU Q 216 19.375 37.567 14.566 1.00115.70 O +ATOM 32035 CB LEU Q 216 20.395 38.929 17.493 1.00 61.97 C +ATOM 32036 CG LEU Q 216 20.866 37.489 17.656 1.00 73.42 C +ATOM 32037 CD1 LEU Q 216 22.131 37.174 16.863 1.00 83.30 C +ATOM 32038 CD2 LEU Q 216 21.142 37.199 19.123 1.00101.80 C +ATOM 32039 N MET Q 217 17.809 38.551 15.836 1.00 92.16 N +ATOM 32040 CA MET Q 217 16.738 37.692 15.355 1.00 68.98 C +ATOM 32041 C MET Q 217 16.595 37.796 13.862 1.00 47.25 C +ATOM 32042 O MET Q 217 16.521 36.797 13.158 1.00 40.18 O +ATOM 32043 CB MET Q 217 15.411 38.023 16.071 1.00 77.48 C +ATOM 32044 CG MET Q 217 14.637 36.788 16.525 1.00 95.04 C +ATOM 32045 SD MET Q 217 13.969 35.849 15.142 1.00123.14 S +ATOM 32046 CE MET Q 217 13.386 34.341 15.929 1.00136.07 C +ATOM 32047 N SER Q 218 16.602 39.015 13.378 1.00 59.19 N +ATOM 32048 CA SER Q 218 16.447 39.284 11.934 1.00100.65 C +ATOM 32049 C SER Q 218 17.534 38.593 11.135 1.00 80.42 C +ATOM 32050 O SER Q 218 17.256 37.906 10.145 1.00103.43 O +ATOM 32051 CB SER Q 218 16.492 40.808 11.664 1.00116.33 C +ATOM 32052 OG SER Q 218 16.158 41.109 10.301 1.00 65.05 O +ATOM 32053 N ALA Q 219 18.764 38.761 11.591 1.00 63.01 N +ATOM 32054 CA ALA Q 219 19.907 38.254 10.859 1.00 73.16 C +ATOM 32055 C ALA Q 219 19.874 36.692 10.820 1.00 67.72 C +ATOM 32056 O ALA Q 219 20.310 36.071 9.851 1.00 54.24 O +ATOM 32057 CB ALA Q 219 21.207 38.798 11.476 1.00 68.88 C +ATOM 32058 N ILE Q 220 19.361 36.079 11.873 1.00 61.47 N +ATOM 32059 CA ILE Q 220 19.333 34.627 11.949 1.00 77.67 C +ATOM 32060 C ILE Q 220 18.307 34.096 10.970 1.00 75.52 C +ATOM 32061 O ILE Q 220 18.529 33.101 10.296 1.00 71.79 O +ATOM 32062 CB ILE Q 220 19.006 34.141 13.393 1.00121.97 C +ATOM 32063 CG1 ILE Q 220 20.204 34.396 14.328 1.00121.66 C +ATOM 32064 CG2 ILE Q 220 18.633 32.657 13.399 1.00125.72 C +ATOM 32065 CD1 ILE Q 220 19.877 34.339 15.812 1.00 79.24 C +ATOM 32066 N GLU Q 221 17.176 34.779 10.881 1.00103.75 N +ATOM 32067 CA GLU Q 221 16.145 34.424 9.900 1.00116.89 C +ATOM 32068 C GLU Q 221 16.738 34.446 8.492 1.00106.74 C +ATOM 32069 O GLU Q 221 16.590 33.489 7.722 1.00100.85 O +ATOM 32070 CB GLU Q 221 14.951 35.403 9.997 1.00131.29 C +ATOM 32071 CG GLU Q 221 14.072 35.173 11.223 1.00147.71 C +ATOM 32072 CD GLU Q 221 13.167 36.343 11.562 1.00141.10 C +ATOM 32073 OE1 GLU Q 221 13.577 37.526 11.377 1.00145.72 O +ATOM 32074 OE2 GLU Q 221 12.041 36.068 12.027 1.00114.86 O +ATOM 32075 N THR Q 222 17.373 35.573 8.159 1.00 92.23 N +ATOM 32076 CA THR Q 222 18.032 35.778 6.868 1.00 77.89 C +ATOM 32077 C THR Q 222 18.980 34.626 6.559 1.00 76.70 C +ATOM 32078 O THR Q 222 18.962 34.074 5.458 1.00 68.45 O +ATOM 32079 CB THR Q 222 18.841 37.095 6.880 1.00 80.83 C +ATOM 32080 OG1 THR Q 222 17.941 38.219 6.862 1.00 76.38 O +ATOM 32081 CG2 THR Q 222 19.838 37.159 5.705 1.00 78.47 C +ATOM 32082 N GLY Q 223 19.803 34.277 7.541 1.00 95.61 N +ATOM 32083 CA GLY Q 223 20.713 33.136 7.423 1.00121.68 C +ATOM 32084 C GLY Q 223 19.999 31.829 7.117 1.00124.93 C +ATOM 32085 O GLY Q 223 20.469 31.037 6.301 1.00114.87 O +ATOM 32086 N VAL Q 224 18.848 31.607 7.758 1.00135.28 N +ATOM 32087 CA VAL Q 224 18.077 30.394 7.523 1.00124.25 C +ATOM 32088 C VAL Q 224 17.608 30.345 6.063 1.00136.01 C +ATOM 32089 O VAL Q 224 17.670 29.304 5.408 1.00116.95 O +ATOM 32090 CB VAL Q 224 16.856 30.307 8.450 1.00114.24 C +ATOM 32091 CG1 VAL Q 224 15.989 29.116 8.045 1.00137.76 C +ATOM 32092 CG2 VAL Q 224 17.297 30.187 9.888 1.00 93.15 C +ATOM 32093 N ILE Q 225 17.143 31.483 5.545 1.00119.75 N +ATOM 32094 CA ILE Q 225 16.727 31.553 4.150 1.00102.44 C +ATOM 32095 C ILE Q 225 17.884 31.200 3.217 1.00 99.18 C +ATOM 32096 O ILE Q 225 17.726 30.329 2.363 1.00 90.58 O +ATOM 32097 CB ILE Q 225 16.156 32.930 3.781 1.00 99.74 C +ATOM 32098 CG1 ILE Q 225 14.825 33.167 4.505 1.00 88.51 C +ATOM 32099 CG2 ILE Q 225 15.918 33.018 2.279 1.00122.09 C +ATOM 32100 CD1 ILE Q 225 14.409 34.623 4.543 1.00110.05 C +ATOM 32101 N PHE Q 226 19.031 31.867 3.386 1.00106.13 N +ATOM 32102 CA PHE Q 226 20.220 31.596 2.562 1.00119.15 C +ATOM 32103 C PHE Q 226 20.617 30.131 2.634 1.00117.78 C +ATOM 32104 O PHE Q 226 21.107 29.569 1.656 1.00122.01 O +ATOM 32105 CB PHE Q 226 21.408 32.470 2.980 1.00127.36 C +ATOM 32106 CG PHE Q 226 21.356 33.888 2.438 1.00146.98 C +ATOM 32107 CD1 PHE Q 226 21.326 34.129 1.067 1.00143.20 C +ATOM 32108 CD2 PHE Q 226 21.394 34.985 3.300 1.00129.63 C +ATOM 32109 CE1 PHE Q 226 21.307 35.427 0.570 1.00120.45 C +ATOM 32110 CE2 PHE Q 226 21.393 36.281 2.809 1.00 97.13 C +ATOM 32111 CZ PHE Q 226 21.343 36.503 1.445 1.00107.09 C +ATOM 32112 N LEU Q 227 20.362 29.492 3.778 1.00145.93 N +ATOM 32113 CA LEU Q 227 20.656 28.045 3.938 1.00141.74 C +ATOM 32114 C LEU Q 227 19.738 27.219 3.102 1.00127.51 C +ATOM 32115 O LEU Q 227 20.188 26.285 2.446 1.00152.42 O +ATOM 32116 CB LEU Q 227 20.459 27.549 5.370 1.00129.84 C +ATOM 32117 CG LEU Q 227 21.680 27.016 6.125 1.00124.98 C +ATOM 32118 CD1 LEU Q 227 22.890 27.720 5.618 1.00104.34 C +ATOM 32119 CD2 LEU Q 227 21.666 27.074 7.660 1.00150.98 C +ATOM 32120 N ILE Q 228 18.449 27.551 3.142 1.00 96.19 N +ATOM 32121 CA ILE Q 228 17.449 26.786 2.401 1.00 98.85 C +ATOM 32122 C ILE Q 228 17.681 26.930 0.903 1.00102.44 C +ATOM 32123 O ILE Q 228 17.742 25.936 0.177 1.00 91.63 O +ATOM 32124 CB ILE Q 228 16.008 27.232 2.701 1.00 95.82 C +ATOM 32125 CG1 ILE Q 228 15.648 26.979 4.167 1.00 98.08 C +ATOM 32126 CG2 ILE Q 228 15.039 26.466 1.825 1.00 90.65 C +ATOM 32127 CD1 ILE Q 228 14.403 27.706 4.653 1.00 75.48 C +ATOM 32128 N ASN Q 229 17.898 28.165 0.462 1.00114.26 N +ATOM 32129 CA ASN Q 229 18.172 28.444 -0.949 1.00128.41 C +ATOM 32130 C ASN Q 229 19.436 27.740 -1.443 1.00111.14 C +ATOM 32131 O ASN Q 229 19.429 27.096 -2.489 1.00136.99 O +ATOM 32132 CB ASN Q 229 18.306 29.954 -1.169 1.00138.11 C +ATOM 32133 CG ASN Q 229 18.177 30.347 -2.625 1.00140.82 C +ATOM 32134 OD1 ASN Q 229 17.566 29.632 -3.427 1.00139.60 O +ATOM 32135 ND2 ASN Q 229 18.723 31.505 -2.965 1.00152.06 N +ATOM 32136 N ASP Q 230 20.492 27.808 -0.639 1.00119.73 N +ATOM 32137 CA ASP Q 230 21.739 27.117 -0.929 1.00121.66 C +ATOM 32138 C ASP Q 230 21.512 25.604 -1.030 1.00137.70 C +ATOM 32139 O ASP Q 230 22.056 24.942 -1.910 1.00145.03 O +ATOM 32140 CB ASP Q 230 22.778 27.427 0.155 1.00136.23 C +ATOM 32141 CG ASP Q 230 24.148 26.891 -0.184 1.00153.73 C +ATOM 32142 OD1 ASP Q 230 24.770 27.449 -1.111 1.00 95.98 O +ATOM 32143 OD2 ASP Q 230 24.574 25.877 0.461 1.00246.30 O +ATOM 32144 N GLY Q 231 20.705 25.053 -0.124 1.00151.25 N +ATOM 32145 CA GLY Q 231 20.420 23.617 -0.122 1.00135.58 C +ATOM 32146 C GLY Q 231 19.606 23.195 -1.332 1.00113.97 C +ATOM 32147 O GLY Q 231 19.788 22.090 -1.863 1.00127.35 O +ATOM 32148 N ILE Q 232 18.699 24.071 -1.760 1.00101.12 N +ATOM 32149 CA ILE Q 232 17.930 23.841 -2.985 1.00114.72 C +ATOM 32150 C ILE Q 232 18.853 23.723 -4.192 1.00114.78 C +ATOM 32151 O ILE Q 232 18.765 22.763 -4.950 1.00116.95 O +ATOM 32152 CB ILE Q 232 16.901 24.969 -3.228 1.00126.48 C +ATOM 32153 CG1 ILE Q 232 15.747 24.844 -2.218 1.00141.13 C +ATOM 32154 CG2 ILE Q 232 16.369 24.933 -4.664 1.00128.08 C +ATOM 32155 CD1 ILE Q 232 14.908 26.096 -2.074 1.00125.10 C +ATOM 32156 N ASP Q 233 19.745 24.699 -4.345 1.00145.20 N +ATOM 32157 CA ASP Q 233 20.743 24.692 -5.416 1.00140.06 C +ATOM 32158 C ASP Q 233 21.565 23.406 -5.383 1.00118.88 C +ATOM 32159 O ASP Q 233 21.759 22.764 -6.413 1.00137.74 O +ATOM 32160 CB ASP Q 233 21.680 25.912 -5.303 1.00164.00 C +ATOM 32161 CG ASP Q 233 20.958 27.245 -5.523 1.00165.92 C +ATOM 32162 OD1 ASP Q 233 19.710 27.257 -5.572 1.00171.44 O +ATOM 32163 OD2 ASP Q 233 21.648 28.284 -5.622 1.00131.45 O +ATOM 32164 N ARG Q 234 22.062 23.039 -4.205 1.00131.62 N +ATOM 32165 CA ARG Q 234 23.028 21.934 -4.085 1.00159.98 C +ATOM 32166 C ARG Q 234 22.381 20.558 -4.027 1.00138.21 C +ATOM 32167 O ARG Q 234 23.076 19.547 -3.954 1.00114.40 O +ATOM 32168 CB ARG Q 234 23.919 22.142 -2.859 1.00182.29 C +ATOM 32169 CG ARG Q 234 24.936 23.245 -3.074 1.00192.05 C +ATOM 32170 CD ARG Q 234 25.460 23.826 -1.781 1.00148.86 C +ATOM 32171 NE ARG Q 234 26.376 24.916 -2.105 1.00125.33 N +ATOM 32172 CZ ARG Q 234 27.649 24.961 -1.736 1.00135.37 C +ATOM 32173 NH1 ARG Q 234 28.140 24.023 -0.930 1.00133.08 N +ATOM 32174 NH2 ARG Q 234 28.411 25.979 -2.116 1.00136.07 N +ATOM 32175 N GLY Q 235 21.052 20.525 -4.080 1.00137.30 N +ATOM 32176 CA GLY Q 235 20.317 19.264 -4.126 1.00119.96 C +ATOM 32177 C GLY Q 235 20.252 18.558 -2.785 1.00128.30 C +ATOM 32178 O GLY Q 235 20.251 17.326 -2.734 1.00131.26 O +ATOM 32179 N LEU Q 236 20.234 19.323 -1.692 1.00148.46 N +ATOM 32180 CA LEU Q 236 19.939 18.738 -0.372 1.00147.04 C +ATOM 32181 C LEU Q 236 18.451 18.411 -0.278 1.00117.30 C +ATOM 32182 O LEU Q 236 18.068 17.303 0.095 1.00103.64 O +ATOM 32183 CB LEU Q 236 20.320 19.686 0.776 1.00174.96 C +ATOM 32184 CG LEU Q 236 21.784 19.697 1.250 1.00168.30 C +ATOM 32185 CD1 LEU Q 236 22.645 20.512 0.298 1.00164.44 C +ATOM 32186 CD2 LEU Q 236 21.878 20.259 2.660 1.00151.37 C +ATOM 32187 N TRP Q 237 17.622 19.371 -0.666 1.00111.85 N +ATOM 32188 CA TRP Q 237 16.171 19.205 -0.623 1.00134.44 C +ATOM 32189 C TRP Q 237 15.517 19.826 -1.870 1.00166.03 C +ATOM 32190 O TRP Q 237 16.167 20.571 -2.620 1.00138.35 O +ATOM 32191 CB TRP Q 237 15.619 19.833 0.651 1.00123.00 C +ATOM 32192 CG TRP Q 237 16.394 21.036 1.083 1.00136.78 C +ATOM 32193 CD1 TRP Q 237 16.470 22.231 0.434 1.00153.57 C +ATOM 32194 CD2 TRP Q 237 17.217 21.162 2.249 1.00147.30 C +ATOM 32195 NE1 TRP Q 237 17.288 23.093 1.121 1.00154.64 N +ATOM 32196 CE2 TRP Q 237 17.742 22.469 2.251 1.00150.51 C +ATOM 32197 CE3 TRP Q 237 17.545 20.307 3.300 1.00166.21 C +ATOM 32198 CZ2 TRP Q 237 18.596 22.935 3.253 1.00137.00 C +ATOM 32199 CZ3 TRP Q 237 18.384 20.780 4.303 1.00160.45 C +ATOM 32200 CH2 TRP Q 237 18.898 22.083 4.269 1.00136.49 C +ATOM 32201 N ASP Q 238 14.248 19.489 -2.104 1.00177.80 N +ATOM 32202 CA ASP Q 238 13.561 19.863 -3.344 1.00175.21 C +ATOM 32203 C ASP Q 238 12.215 20.537 -3.092 1.00157.51 C +ATOM 32204 O ASP Q 238 11.504 20.198 -2.139 1.00119.74 O +ATOM 32205 CB ASP Q 238 13.359 18.644 -4.255 1.00172.74 C +ATOM 32206 CG ASP Q 238 14.660 17.932 -4.590 1.00155.26 C +ATOM 32207 OD1 ASP Q 238 15.136 17.161 -3.734 1.00145.56 O +ATOM 32208 OD2 ASP Q 238 15.206 18.145 -5.696 1.00137.24 O +ATOM 32209 N LEU Q 239 11.852 21.449 -3.996 1.00143.01 N +ATOM 32210 CA LEU Q 239 10.596 22.176 -3.905 1.00145.01 C +ATOM 32211 C LEU Q 239 9.426 21.299 -4.341 1.00155.59 C +ATOM 32212 O LEU Q 239 9.554 20.466 -5.239 1.00141.99 O +ATOM 32213 CB LEU Q 239 10.632 23.429 -4.783 1.00171.29 C +ATOM 32214 CG LEU Q 239 11.410 24.656 -4.313 1.00177.43 C +ATOM 32215 CD1 LEU Q 239 11.219 25.815 -5.282 1.00191.59 C +ATOM 32216 CD2 LEU Q 239 10.974 25.066 -2.923 1.00173.72 C +ATOM 32217 N GLN Q 240 8.284 21.495 -3.687 1.00159.50 N +ATOM 32218 CA GLN Q 240 7.026 20.876 -4.118 1.00131.94 C +ATOM 32219 C GLN Q 240 6.732 21.227 -5.570 1.00139.22 C +ATOM 32220 O GLN Q 240 6.592 20.344 -6.413 1.00166.26 O +ATOM 32221 CB GLN Q 240 5.869 21.349 -3.223 1.00126.71 C +ATOM 32222 CG GLN Q 240 4.557 20.617 -3.470 1.00108.97 C +ATOM 32223 CD GLN Q 240 4.643 19.144 -3.102 1.00134.69 C +ATOM 32224 OE1 GLN Q 240 4.557 18.780 -1.921 1.00161.63 O +ATOM 32225 NE2 GLN Q 240 4.881 18.294 -4.097 1.00145.45 N +ATOM 32226 N ASN Q 241 6.680 22.526 -5.845 1.00136.34 N +ATOM 32227 CA ASN Q 241 6.453 23.037 -7.184 1.00120.81 C +ATOM 32228 C ASN Q 241 7.737 23.552 -7.801 1.00141.67 C +ATOM 32229 O ASN Q 241 8.272 24.602 -7.387 1.00170.58 O +ATOM 32230 CB ASN Q 241 5.452 24.173 -7.125 1.00111.66 C +ATOM 32231 CG ASN Q 241 4.072 23.734 -7.524 1.00121.36 C +ATOM 32232 OD1 ASN Q 241 3.638 23.998 -8.646 1.00145.68 O +ATOM 32233 ND2 ASN Q 241 3.370 23.056 -6.622 1.00129.32 N +ATOM 32234 N LYS Q 242 8.223 22.840 -8.814 1.00131.62 N +ATOM 32235 CA LYS Q 242 9.459 23.241 -9.494 1.00153.00 C +ATOM 32236 C LYS Q 242 9.251 24.571 -10.220 1.00162.76 C +ATOM 32237 O LYS Q 242 10.198 25.346 -10.414 1.00119.84 O +ATOM 32238 CB LYS Q 242 9.916 22.153 -10.470 1.00159.22 C +ATOM 32239 CG LYS Q 242 9.948 20.754 -9.860 1.00169.42 C +ATOM 32240 CD LYS Q 242 11.301 20.083 -10.028 1.00165.56 C +ATOM 32241 CE LYS Q 242 11.766 19.446 -8.727 1.00161.30 C +ATOM 32242 NZ LYS Q 242 13.011 18.648 -8.894 1.00174.24 N +ATOM 32243 N ALA Q 243 7.986 24.837 -10.554 1.00197.97 N +ATOM 32244 CA ALA Q 243 7.543 26.114 -11.121 1.00199.58 C +ATOM 32245 C ALA Q 243 7.782 27.275 -10.165 1.00197.69 C +ATOM 32246 O ALA Q 243 7.803 28.431 -10.593 1.00211.75 O +ATOM 32247 CB ALA Q 243 6.062 26.044 -11.484 1.00194.85 C +ATOM 32248 N GLU Q 244 7.945 26.976 -8.874 1.00187.59 N +ATOM 32249 CA GLU Q 244 8.131 28.029 -7.883 1.00159.48 C +ATOM 32250 C GLU Q 244 9.602 28.347 -7.636 1.00149.58 C +ATOM 32251 O GLU Q 244 9.911 29.054 -6.693 1.00130.82 O +ATOM 32252 CB GLU Q 244 7.448 27.659 -6.567 1.00152.83 C +ATOM 32253 CG GLU Q 244 5.939 27.746 -6.608 1.00157.28 C +ATOM 32254 CD GLU Q 244 5.316 27.644 -5.224 1.00166.35 C +ATOM 32255 OE1 GLU Q 244 5.215 26.503 -4.703 1.00134.43 O +ATOM 32256 OE2 GLU Q 244 4.860 28.699 -4.704 1.00118.99 O +ATOM 32257 N ARG Q 245 10.499 27.815 -8.467 1.00145.62 N +ATOM 32258 CA ARG Q 245 11.913 28.167 -8.382 1.00157.85 C +ATOM 32259 C ARG Q 245 12.168 29.671 -8.510 1.00188.68 C +ATOM 32260 O ARG Q 245 13.061 30.201 -7.849 1.00230.77 O +ATOM 32261 CB ARG Q 245 12.737 27.452 -9.440 1.00156.40 C +ATOM 32262 CG ARG Q 245 14.245 27.642 -9.260 1.00163.17 C +ATOM 32263 CD ARG Q 245 15.080 26.828 -10.266 1.00164.96 C +ATOM 32264 NE ARG Q 245 15.564 25.571 -9.688 1.00164.13 N +ATOM 32265 CZ ARG Q 245 16.524 25.479 -8.765 1.00177.85 C +ATOM 32266 NH1 ARG Q 245 17.098 26.567 -8.280 1.00185.77 N +ATOM 32267 NH2 ARG Q 245 16.905 24.293 -8.303 1.00164.31 N +ATOM 32268 N GLN Q 246 11.396 30.350 -9.357 1.00194.27 N +ATOM 32269 CA GLN Q 246 11.603 31.784 -9.593 1.00170.10 C +ATOM 32270 C GLN Q 246 10.734 32.638 -8.666 1.00161.10 C +ATOM 32271 O GLN Q 246 10.460 33.797 -8.959 1.00175.95 O +ATOM 32272 CB GLN Q 246 11.333 32.145 -11.059 1.00158.16 C +ATOM 32273 CG GLN Q 246 12.374 31.628 -12.033 1.00162.18 C +ATOM 32274 CD GLN Q 246 12.232 30.144 -12.289 1.00196.34 C +ATOM 32275 OE1 GLN Q 246 11.121 29.640 -12.503 1.00232.28 O +ATOM 32276 NE2 GLN Q 246 13.355 29.433 -12.296 1.00208.80 N +ATOM 32277 N ASN Q 247 10.299 32.051 -7.555 1.00136.38 N +ATOM 32278 CA ASN Q 247 9.689 32.792 -6.456 1.00132.97 C +ATOM 32279 C ASN Q 247 10.413 34.111 -6.180 1.00144.17 C +ATOM 32280 O ASN Q 247 11.648 34.153 -6.165 1.00161.54 O +ATOM 32281 CB ASN Q 247 9.726 31.932 -5.192 1.00150.23 C +ATOM 32282 CG ASN Q 247 8.633 32.287 -4.214 1.00183.57 C +ATOM 32283 OD1 ASN Q 247 8.890 32.847 -3.144 1.00175.27 O +ATOM 32284 ND2 ASN Q 247 7.400 31.936 -4.564 1.00224.27 N +ATOM 32285 N ASP Q 248 9.647 35.177 -5.932 1.00168.15 N +ATOM 32286 CA ASP Q 248 10.216 36.524 -5.691 1.00179.39 C +ATOM 32287 C ASP Q 248 11.292 36.511 -4.601 1.00173.26 C +ATOM 32288 O ASP Q 248 12.376 37.088 -4.754 1.00167.56 O +ATOM 32289 CB ASP Q 248 9.119 37.515 -5.266 1.00168.76 C +ATOM 32290 CG ASP Q 248 8.178 37.879 -6.396 1.00169.97 C +ATOM 32291 OD1 ASP Q 248 8.634 38.019 -7.550 1.00185.87 O +ATOM 32292 OD2 ASP Q 248 6.971 38.038 -6.124 1.00188.00 O +ATOM 32293 N ILE Q 249 10.967 35.855 -3.493 1.00154.84 N +ATOM 32294 CA ILE Q 249 11.844 35.798 -2.346 1.00136.51 C +ATOM 32295 C ILE Q 249 13.116 35.020 -2.692 1.00132.90 C +ATOM 32296 O ILE Q 249 14.238 35.487 -2.455 1.00154.06 O +ATOM 32297 CB ILE Q 249 11.121 35.142 -1.152 1.00143.13 C +ATOM 32298 CG1 ILE Q 249 9.901 35.981 -0.737 1.00120.34 C +ATOM 32299 CG2 ILE Q 249 12.070 35.004 0.030 1.00181.48 C +ATOM 32300 CD1 ILE Q 249 8.863 35.228 0.076 1.00106.77 C +ATOM 32301 N LEU Q 250 12.934 33.832 -3.261 1.00132.64 N +ATOM 32302 CA LEU Q 250 14.061 32.961 -3.606 1.00141.81 C +ATOM 32303 C LEU Q 250 15.049 33.610 -4.583 1.00143.09 C +ATOM 32304 O LEU Q 250 16.263 33.426 -4.454 1.00121.99 O +ATOM 32305 CB LEU Q 250 13.559 31.635 -4.183 1.00129.83 C +ATOM 32306 CG LEU Q 250 13.074 30.617 -3.148 1.00129.97 C +ATOM 32307 CD1 LEU Q 250 12.336 29.462 -3.800 1.00137.47 C +ATOM 32308 CD2 LEU Q 250 14.253 30.090 -2.348 1.00157.17 C +ATOM 32309 N VAL Q 251 14.526 34.366 -5.544 1.00151.77 N +ATOM 32310 CA VAL Q 251 15.381 35.055 -6.510 1.00158.11 C +ATOM 32311 C VAL Q 251 16.022 36.301 -5.902 1.00158.83 C +ATOM 32312 O VAL Q 251 17.077 36.752 -6.358 1.00157.61 O +ATOM 32313 CB VAL Q 251 14.616 35.439 -7.800 1.00158.31 C +ATOM 32314 CG1 VAL Q 251 13.968 34.205 -8.425 1.00146.40 C +ATOM 32315 CG2 VAL Q 251 13.589 36.538 -7.538 1.00140.63 C +ATOM 32316 N LYS Q 252 15.371 36.867 -4.891 1.00156.43 N +ATOM 32317 CA LYS Q 252 15.926 38.007 -4.167 1.00158.04 C +ATOM 32318 C LYS Q 252 17.193 37.593 -3.393 1.00187.42 C +ATOM 32319 O LYS Q 252 18.237 38.253 -3.480 1.00168.01 O +ATOM 32320 CB LYS Q 252 14.858 38.571 -3.229 1.00129.74 C +ATOM 32321 CG LYS Q 252 15.302 39.746 -2.378 1.00131.45 C +ATOM 32322 CD LYS Q 252 14.162 40.191 -1.469 1.00137.44 C +ATOM 32323 CE LYS Q 252 14.628 40.386 -0.030 1.00139.13 C +ATOM 32324 NZ LYS Q 252 13.496 40.563 0.920 1.00121.85 N +ATOM 32325 N TYR Q 253 17.114 36.460 -2.694 1.00208.74 N +ATOM 32326 CA TYR Q 253 18.246 35.944 -1.909 1.00174.38 C +ATOM 32327 C TYR Q 253 19.286 35.286 -2.802 1.00175.06 C +ATOM 32328 O TYR Q 253 20.486 35.330 -2.510 1.00165.38 O +ATOM 32329 CB TYR Q 253 17.765 34.972 -0.823 1.00147.64 C +ATOM 32330 CG TYR Q 253 17.037 35.699 0.294 1.00157.40 C +ATOM 32331 CD1 TYR Q 253 17.739 36.298 1.335 1.00149.77 C +ATOM 32332 CD2 TYR Q 253 15.646 35.866 0.264 1.00163.50 C +ATOM 32333 CE1 TYR Q 253 17.071 37.007 2.327 1.00152.56 C +ATOM 32334 CE2 TYR Q 253 14.971 36.579 1.256 1.00126.20 C +ATOM 32335 CZ TYR Q 253 15.688 37.151 2.280 1.00131.92 C +ATOM 32336 OH TYR Q 253 15.045 37.787 3.306 1.00100.86 O +ATOM 32337 N ARG Q 254 18.820 34.693 -3.900 1.00161.52 N +ATOM 32338 CA ARG Q 254 19.715 34.213 -4.951 1.00163.62 C +ATOM 32339 C ARG Q 254 20.566 35.365 -5.493 1.00150.74 C +ATOM 32340 O ARG Q 254 21.764 35.199 -5.751 1.00118.23 O +ATOM 32341 CB ARG Q 254 18.911 33.579 -6.096 1.00168.16 C +ATOM 32342 CG ARG Q 254 19.781 32.949 -7.174 1.00179.91 C +ATOM 32343 CD ARG Q 254 19.017 31.991 -8.074 1.00164.13 C +ATOM 32344 NE ARG Q 254 18.535 30.801 -7.378 1.00184.34 N +ATOM 32345 CZ ARG Q 254 17.267 30.558 -7.060 1.00182.51 C +ATOM 32346 NH1 ARG Q 254 16.311 31.419 -7.366 1.00164.46 N +ATOM 32347 NH2 ARG Q 254 16.955 29.434 -6.419 1.00187.35 N +ATOM 32348 N HIS Q 255 19.930 36.526 -5.660 1.00145.06 N +ATOM 32349 CA HIS Q 255 20.605 37.721 -6.159 1.00154.45 C +ATOM 32350 C HIS Q 255 21.634 38.283 -5.174 1.00175.14 C +ATOM 32351 O HIS Q 255 22.671 38.804 -5.582 1.00176.72 O +ATOM 32352 CB HIS Q 255 19.585 38.803 -6.543 1.00166.31 C +ATOM 32353 CG HIS Q 255 19.412 38.958 -8.022 1.00199.13 C +ATOM 32354 ND1 HIS Q 255 18.728 38.043 -8.792 1.00208.67 N +ATOM 32355 CD2 HIS Q 255 19.891 39.888 -8.883 1.00217.68 C +ATOM 32356 CE1 HIS Q 255 18.765 38.417 -10.059 1.00193.87 C +ATOM 32357 NE2 HIS Q 255 19.467 39.533 -10.141 1.00211.32 N +ATOM 32358 N MET Q 256 21.354 38.185 -3.877 1.00184.71 N +ATOM 32359 CA MET Q 256 22.297 38.690 -2.872 1.00152.17 C +ATOM 32360 C MET Q 256 23.596 37.856 -2.844 1.00152.63 C +ATOM 32361 O MET Q 256 24.646 38.360 -2.434 1.00112.23 O +ATOM 32362 CB MET Q 256 21.631 38.744 -1.490 1.00160.21 C +ATOM 32363 CG MET Q 256 20.317 39.521 -1.475 1.00166.72 C +ATOM 32364 SD MET Q 256 19.754 40.076 0.145 1.00204.90 S +ATOM 32365 CE MET Q 256 20.990 41.325 0.508 1.00199.85 C +ATOM 32366 N SER Q 257 23.518 36.594 -3.294 1.00152.50 N +ATOM 32367 CA SER Q 257 24.690 35.687 -3.365 1.00115.11 C +ATOM 32368 C SER Q 257 25.634 36.028 -4.508 1.00115.86 C +ATOM 32369 O SER Q 257 26.550 36.830 -4.363 1.00 62.98 O +ATOM 32370 CB SER Q 257 24.236 34.231 -3.530 1.00 84.10 C +ATOM 32371 OG SER Q 257 23.187 33.938 -2.638 1.00 77.73 O +TER 32372 SER Q 257 +ATOM 32373 N LEU R 2 3.443 54.964 20.571 1.00158.47 N +ATOM 32374 CA LEU R 2 4.933 54.933 20.385 1.00169.74 C +ATOM 32375 C LEU R 2 5.660 54.845 21.754 1.00182.45 C +ATOM 32376 O LEU R 2 6.304 55.811 22.221 1.00136.59 O +ATOM 32377 CB LEU R 2 5.411 56.135 19.555 1.00155.28 C +ATOM 32378 CG LEU R 2 4.892 56.301 18.105 1.00119.63 C +ATOM 32379 CD1 LEU R 2 5.482 57.575 17.505 1.00109.27 C +ATOM 32380 CD2 LEU R 2 5.160 55.103 17.189 1.00 89.31 C +ATOM 32381 N THR R 3 5.396 53.727 22.435 1.00219.43 N +ATOM 32382 CA THR R 3 6.161 53.250 23.596 1.00204.50 C +ATOM 32383 C THR R 3 6.322 51.713 23.531 1.00176.94 C +ATOM 32384 O THR R 3 6.939 51.089 24.405 1.00106.93 O +ATOM 32385 CB THR R 3 5.483 53.621 24.940 1.00195.76 C +ATOM 32386 OG1 THR R 3 4.253 52.888 25.085 1.00150.26 O +ATOM 32387 CG2 THR R 3 5.240 55.137 25.041 1.00159.21 C +ATOM 32388 N ALA R 4 5.691 51.108 22.531 1.00150.77 N +ATOM 32389 CA ALA R 4 6.079 49.780 22.071 1.00111.58 C +ATOM 32390 C ALA R 4 7.408 49.914 21.296 1.00 78.78 C +ATOM 32391 O ALA R 4 8.011 50.973 21.264 1.00 52.30 O +ATOM 32392 CB ALA R 4 4.948 49.164 21.232 1.00 91.38 C +ATOM 32393 N PRO R 5 7.900 48.829 20.713 1.00 85.11 N +ATOM 32394 CA PRO R 5 9.270 49.016 20.272 1.00 85.47 C +ATOM 32395 C PRO R 5 9.379 49.845 18.974 1.00 75.84 C +ATOM 32396 O PRO R 5 8.400 50.025 18.272 1.00 50.61 O +ATOM 32397 CB PRO R 5 9.765 47.558 20.092 1.00 99.24 C +ATOM 32398 CG PRO R 5 8.533 46.741 19.794 1.00 98.86 C +ATOM 32399 CD PRO R 5 7.333 47.526 20.280 1.00 99.61 C +ATOM 32400 N PRO R 6 10.599 50.190 18.576 1.00 75.19 N +ATOM 32401 CA PRO R 6 10.906 50.601 17.196 1.00 74.40 C +ATOM 32402 C PRO R 6 11.036 49.461 16.188 1.00 68.08 C +ATOM 32403 O PRO R 6 11.421 48.363 16.541 1.00 79.67 O +ATOM 32404 CB PRO R 6 12.236 51.339 17.329 1.00 83.25 C +ATOM 32405 CG PRO R 6 12.823 50.891 18.620 1.00 96.69 C +ATOM 32406 CD PRO R 6 11.751 50.279 19.480 1.00 77.42 C +ATOM 32407 N LYS R 7 10.726 49.731 14.932 1.00 81.71 N +ATOM 32408 CA LYS R 7 10.802 48.710 13.884 1.00118.11 C +ATOM 32409 C LYS R 7 12.135 48.730 13.129 1.00131.21 C +ATOM 32410 O LYS R 7 12.937 49.658 13.273 1.00 92.75 O +ATOM 32411 CB LYS R 7 9.633 48.856 12.898 1.00150.46 C +ATOM 32412 CG LYS R 7 8.280 48.511 13.483 1.00159.35 C +ATOM 32413 CD LYS R 7 7.426 49.741 13.782 1.00158.53 C +ATOM 32414 CE LYS R 7 5.989 49.335 14.056 1.00143.77 C +ATOM 32415 NZ LYS R 7 5.312 50.284 14.974 1.00141.45 N +ATOM 32416 N GLU R 8 12.342 47.712 12.292 1.00154.03 N +ATOM 32417 CA GLU R 8 13.657 47.418 11.721 1.00166.85 C +ATOM 32418 C GLU R 8 14.189 48.523 10.771 1.00134.68 C +ATOM 32419 O GLU R 8 13.605 48.818 9.737 1.00111.88 O +ATOM 32420 CB GLU R 8 13.656 46.024 11.057 1.00191.36 C +ATOM 32421 CG GLU R 8 14.344 44.871 11.863 1.00201.84 C +ATOM 32422 CD GLU R 8 13.420 43.696 12.235 1.00187.76 C +ATOM 32423 OE1 GLU R 8 12.307 43.988 12.747 1.00175.03 O +ATOM 32424 OE2 GLU R 8 13.842 42.494 12.121 1.00122.79 O +ATOM 32425 N ALA R 9 15.298 49.142 11.167 1.00128.07 N +ATOM 32426 CA ALA R 9 16.055 50.069 10.331 1.00108.19 C +ATOM 32427 C ALA R 9 17.248 49.367 9.647 1.00113.80 C +ATOM 32428 O ALA R 9 18.204 48.958 10.313 1.00136.81 O +ATOM 32429 CB ALA R 9 16.559 51.222 11.186 1.00 93.89 C +ATOM 32430 N ALA R 10 17.165 49.225 8.324 1.00101.27 N +ATOM 32431 CA ALA R 10 18.125 48.461 7.499 1.00102.87 C +ATOM 32432 C ALA R 10 17.787 46.972 7.478 1.00121.97 C +ATOM 32433 O ALA R 10 17.058 46.484 8.348 1.00 89.26 O +ATOM 32434 CB ALA R 10 19.570 48.674 7.942 1.00 95.28 C +ATOM 32435 N ARG R 11 18.325 46.268 6.473 1.00149.47 N +ATOM 32436 CA ARG R 11 18.101 44.828 6.289 1.00137.54 C +ATOM 32437 C ARG R 11 19.348 44.031 6.678 1.00119.24 C +ATOM 32438 O ARG R 11 20.475 44.499 6.518 1.00103.32 O +ATOM 32439 CB ARG R 11 17.747 44.507 4.822 1.00129.26 C +ATOM 32440 CG ARG R 11 18.884 44.729 3.830 1.00147.30 C +ATOM 32441 CD ARG R 11 18.351 45.051 2.435 1.00142.70 C +ATOM 32442 NE ARG R 11 18.587 46.446 2.064 1.00152.75 N +ATOM 32443 CZ ARG R 11 18.238 46.978 0.894 1.00148.14 C +ATOM 32444 NH1 ARG R 11 17.699 46.214 -0.044 1.00159.90 N +ATOM 32445 NH2 ARG R 11 18.459 48.266 0.644 1.00128.59 N +ATOM 32446 N PRO R 12 19.152 42.806 7.171 1.00104.23 N +ATOM 32447 CA PRO R 12 20.288 41.920 7.209 1.00102.43 C +ATOM 32448 C PRO R 12 20.790 41.643 5.778 1.00 86.20 C +ATOM 32449 O PRO R 12 20.105 40.996 4.987 1.00142.47 O +ATOM 32450 CB PRO R 12 19.721 40.635 7.875 1.00116.87 C +ATOM 32451 CG PRO R 12 18.380 41.002 8.430 1.00 96.33 C +ATOM 32452 CD PRO R 12 17.903 42.117 7.544 1.00114.96 C +ATOM 32453 N THR R 13 21.981 42.102 5.468 1.00 58.12 N +ATOM 32454 CA THR R 13 22.705 41.606 4.312 1.00 67.60 C +ATOM 32455 C THR R 13 23.547 40.361 4.657 1.00 78.09 C +ATOM 32456 O THR R 13 23.881 40.146 5.824 1.00162.78 O +ATOM 32457 CB THR R 13 23.619 42.719 3.793 1.00 75.22 C +ATOM 32458 OG1 THR R 13 24.177 42.350 2.526 1.00 73.51 O +ATOM 32459 CG2 THR R 13 24.776 43.035 4.799 1.00 85.45 C +ATOM 32460 N LEU R 14 23.982 39.587 3.667 1.00 83.31 N +ATOM 32461 CA LEU R 14 25.045 38.604 3.954 1.00101.49 C +ATOM 32462 C LEU R 14 26.412 39.317 4.122 1.00100.23 C +ATOM 32463 O LEU R 14 26.527 40.474 3.756 1.00 78.23 O +ATOM 32464 CB LEU R 14 25.106 37.464 2.938 1.00112.27 C +ATOM 32465 CG LEU R 14 25.247 37.812 1.465 1.00120.64 C +ATOM 32466 CD1 LEU R 14 26.069 36.753 0.749 1.00133.21 C +ATOM 32467 CD2 LEU R 14 23.869 37.914 0.855 1.00 95.30 C +ATOM 32468 N MET R 15 27.372 38.697 4.821 1.00132.07 N +ATOM 32469 CA MET R 15 28.423 39.478 5.546 1.00139.91 C +ATOM 32470 C MET R 15 29.382 40.109 4.565 1.00123.72 C +ATOM 32471 O MET R 15 29.957 39.419 3.728 1.00103.20 O +ATOM 32472 CB MET R 15 29.235 38.664 6.548 1.00123.35 C +ATOM 32473 CG MET R 15 30.349 39.478 7.263 1.00113.16 C +ATOM 32474 SD MET R 15 30.049 39.582 8.909 1.00100.69 S +ATOM 32475 CE MET R 15 31.681 39.182 9.545 1.00112.85 C +ATOM 32476 N PRO R 16 29.537 41.435 4.658 1.00101.79 N +ATOM 32477 CA PRO R 16 30.255 42.233 3.666 1.00101.25 C +ATOM 32478 C PRO R 16 31.746 41.919 3.609 1.00 87.56 C +ATOM 32479 O PRO R 16 32.574 42.659 4.141 1.00 92.61 O +ATOM 32480 CB PRO R 16 29.995 43.676 4.127 1.00116.82 C +ATOM 32481 CG PRO R 16 29.675 43.545 5.574 1.00112.61 C +ATOM 32482 CD PRO R 16 28.905 42.282 5.685 1.00 90.30 C +ATOM 32483 N ARG R 17 32.090 40.879 2.870 1.00104.70 N +ATOM 32484 CA ARG R 17 33.482 40.592 2.561 1.00130.28 C +ATOM 32485 C ARG R 17 33.933 41.400 1.334 1.00108.53 C +ATOM 32486 O ARG R 17 33.158 41.549 0.402 1.00108.11 O +ATOM 32487 CB ARG R 17 33.644 39.072 2.361 1.00131.39 C +ATOM 32488 CG ARG R 17 33.866 38.312 3.670 1.00144.91 C +ATOM 32489 CD ARG R 17 33.608 36.822 3.546 1.00159.42 C +ATOM 32490 NE ARG R 17 32.187 36.512 3.577 1.00149.25 N +ATOM 32491 CZ ARG R 17 31.682 35.306 3.335 1.00 98.60 C +ATOM 32492 NH1 ARG R 17 32.496 34.301 3.044 1.00 86.31 N +ATOM 32493 NH2 ARG R 17 30.369 35.109 3.403 1.00 72.84 N +ATOM 32494 N ALA R 18 35.196 41.835 1.304 1.00 84.93 N +ATOM 32495 CA ALA R 18 35.716 42.557 0.155 1.00 87.96 C +ATOM 32496 C ALA R 18 36.767 41.767 -0.691 1.00 98.67 C +ATOM 32497 O ALA R 18 36.429 40.763 -1.351 1.00116.91 O +ATOM 32498 CB ALA R 18 36.272 43.882 0.609 1.00 89.94 C +ATOM 32499 N GLN R 19 37.993 42.285 -0.787 1.00103.23 N +ATOM 32500 CA GLN R 19 38.887 41.954 -1.918 1.00142.22 C +ATOM 32501 C GLN R 19 39.438 40.541 -1.790 1.00140.58 C +ATOM 32502 O GLN R 19 39.393 39.738 -2.742 1.00181.86 O +ATOM 32503 CB GLN R 19 40.059 42.942 -1.991 1.00168.04 C +ATOM 32504 CG GLN R 19 40.991 42.744 -3.186 1.00170.48 C +ATOM 32505 CD GLN R 19 40.251 42.771 -4.512 1.00180.40 C +ATOM 32506 OE1 GLN R 19 39.718 43.805 -4.918 1.00176.46 O +ATOM 32507 NE2 GLN R 19 40.196 41.625 -5.185 1.00197.33 N +ATOM 32508 N SER R 20 39.954 40.257 -0.603 1.00105.76 N +ATOM 32509 CA SER R 20 40.372 38.929 -0.239 1.00108.98 C +ATOM 32510 C SER R 20 39.355 37.872 -0.717 1.00135.21 C +ATOM 32511 O SER R 20 39.726 36.874 -1.346 1.00145.53 O +ATOM 32512 CB SER R 20 40.526 38.871 1.281 1.00121.61 C +ATOM 32513 OG SER R 20 41.321 39.947 1.755 1.00 79.91 O +ATOM 32514 N TYR R 21 38.075 38.087 -0.398 1.00143.72 N +ATOM 32515 CA TYR R 21 36.987 37.186 -0.813 1.00145.26 C +ATOM 32516 C TYR R 21 36.949 36.993 -2.331 1.00147.46 C +ATOM 32517 O TYR R 21 36.852 35.867 -2.825 1.00100.60 O +ATOM 32518 CB TYR R 21 35.632 37.731 -0.325 1.00155.09 C +ATOM 32519 CG TYR R 21 34.456 36.845 -0.668 1.00181.50 C +ATOM 32520 CD1 TYR R 21 34.222 35.660 0.033 1.00189.23 C +ATOM 32521 CD2 TYR R 21 33.601 37.166 -1.718 1.00190.23 C +ATOM 32522 CE1 TYR R 21 33.173 34.823 -0.294 1.00180.94 C +ATOM 32523 CE2 TYR R 21 32.539 36.328 -2.049 1.00196.41 C +ATOM 32524 CZ TYR R 21 32.332 35.152 -1.330 1.00167.63 C +ATOM 32525 OH TYR R 21 31.274 34.314 -1.617 1.00 79.98 O +ATOM 32526 N LYS R 22 36.967 38.106 -3.061 1.00187.06 N +ATOM 32527 CA LYS R 22 36.865 38.083 -4.522 1.00183.64 C +ATOM 32528 C LYS R 22 37.999 37.292 -5.160 1.00171.60 C +ATOM 32529 O LYS R 22 37.781 36.535 -6.110 1.00201.89 O +ATOM 32530 CB LYS R 22 36.863 39.509 -5.075 1.00169.28 C +ATOM 32531 CG LYS R 22 35.482 40.119 -5.170 1.00169.99 C +ATOM 32532 CD LYS R 22 34.782 39.649 -6.454 1.00176.32 C +ATOM 32533 CE LYS R 22 34.838 40.746 -7.522 1.00169.34 C +ATOM 32534 NZ LYS R 22 34.061 41.945 -7.109 1.00187.44 N +ATOM 32535 N ASP R 23 39.202 37.457 -4.616 1.00151.97 N +ATOM 32536 CA ASP R 23 40.354 36.663 -5.038 1.00161.57 C +ATOM 32537 C ASP R 23 40.163 35.184 -4.700 1.00159.07 C +ATOM 32538 O ASP R 23 40.417 34.307 -5.529 1.00147.53 O +ATOM 32539 CB ASP R 23 41.621 37.172 -4.351 1.00163.45 C +ATOM 32540 CG ASP R 23 42.013 38.543 -4.811 1.00153.80 C +ATOM 32541 OD1 ASP R 23 41.927 38.787 -6.030 1.00136.21 O +ATOM 32542 OD2 ASP R 23 42.437 39.358 -3.957 1.00181.59 O +ATOM 32543 N LEU R 24 39.689 34.930 -3.483 1.00146.23 N +ATOM 32544 CA LEU R 24 39.558 33.576 -2.953 1.00150.54 C +ATOM 32545 C LEU R 24 38.536 32.743 -3.733 1.00155.67 C +ATOM 32546 O LEU R 24 38.712 31.529 -3.924 1.00162.81 O +ATOM 32547 CB LEU R 24 39.148 33.648 -1.476 1.00150.49 C +ATOM 32548 CG LEU R 24 38.965 32.328 -0.719 1.00151.73 C +ATOM 32549 CD1 LEU R 24 40.291 31.823 -0.157 1.00154.81 C +ATOM 32550 CD2 LEU R 24 37.949 32.501 0.398 1.00149.28 C +ATOM 32551 N THR R 25 37.461 33.396 -4.173 1.00171.42 N +ATOM 32552 CA THR R 25 36.385 32.717 -4.910 1.00172.91 C +ATOM 32553 C THR R 25 36.778 32.380 -6.360 1.00151.25 C +ATOM 32554 O THR R 25 36.576 31.256 -6.818 1.00 82.68 O +ATOM 32555 CB THR R 25 35.095 33.567 -4.918 1.00175.51 C +ATOM 32556 OG1 THR R 25 35.414 34.928 -5.265 1.00235.99 O +ATOM 32557 CG2 THR R 25 34.426 33.524 -3.549 1.00133.49 C +ATOM 32558 N HIS R 26 37.357 33.361 -7.054 1.00165.29 N +ATOM 32559 CA HIS R 26 37.735 33.220 -8.461 1.00152.29 C +ATOM 32560 C HIS R 26 39.108 32.541 -8.610 1.00145.28 C +ATOM 32561 O HIS R 26 39.902 32.889 -9.479 1.00174.88 O +ATOM 32562 CB HIS R 26 37.715 34.605 -9.155 1.00156.72 C +ATOM 32563 CG HIS R 26 36.353 35.241 -9.215 1.00169.09 C +ATOM 32564 ND1 HIS R 26 35.708 35.732 -8.099 1.00173.32 N +ATOM 32565 CD2 HIS R 26 35.511 35.457 -10.256 1.00169.23 C +ATOM 32566 CE1 HIS R 26 34.522 36.201 -8.445 1.00160.19 C +ATOM 32567 NE2 HIS R 26 34.377 36.047 -9.749 1.00161.78 N +ATOM 32568 N LEU R 27 39.406 31.589 -7.736 1.00128.07 N +ATOM 32569 CA LEU R 27 40.645 30.831 -7.845 1.00127.46 C +ATOM 32570 C LEU R 27 40.403 29.626 -8.750 1.00114.27 C +ATOM 32571 O LEU R 27 39.415 28.917 -8.581 1.00102.43 O +ATOM 32572 CB LEU R 27 41.140 30.374 -6.457 1.00150.84 C +ATOM 32573 CG LEU R 27 42.046 31.360 -5.710 1.00158.72 C +ATOM 32574 CD1 LEU R 27 42.213 30.964 -4.252 1.00154.42 C +ATOM 32575 CD2 LEU R 27 43.411 31.464 -6.389 1.00176.52 C +ATOM 32576 N PRO R 28 41.346 29.347 -9.665 1.00110.46 N +ATOM 32577 CA PRO R 28 41.244 28.178 -10.554 1.00114.11 C +ATOM 32578 C PRO R 28 41.151 26.869 -9.796 1.00114.86 C +ATOM 32579 O PRO R 28 41.976 26.615 -8.930 1.00179.01 O +ATOM 32580 CB PRO R 28 42.546 28.225 -11.350 1.00118.74 C +ATOM 32581 CG PRO R 28 43.501 28.995 -10.481 1.00111.33 C +ATOM 32582 CD PRO R 28 42.661 30.007 -9.764 1.00109.61 C +ATOM 32583 N ALA R 29 40.154 26.050 -10.110 1.00119.21 N +ATOM 32584 CA ALA R 29 39.821 24.879 -9.284 1.00106.56 C +ATOM 32585 C ALA R 29 40.873 23.732 -9.420 1.00 97.85 C +ATOM 32586 O ALA R 29 41.512 23.573 -10.454 1.00 64.21 O +ATOM 32587 CB ALA R 29 38.412 24.379 -9.609 1.00 88.50 C +ATOM 32588 N PRO R 30 41.088 22.967 -8.342 1.00104.78 N +ATOM 32589 CA PRO R 30 41.996 21.821 -8.328 1.00101.92 C +ATOM 32590 C PRO R 30 41.363 20.613 -8.991 1.00100.16 C +ATOM 32591 O PRO R 30 40.178 20.654 -9.354 1.00 77.89 O +ATOM 32592 CB PRO R 30 42.165 21.536 -6.846 1.00123.16 C +ATOM 32593 CG PRO R 30 40.881 21.993 -6.223 1.00133.25 C +ATOM 32594 CD PRO R 30 40.397 23.149 -7.051 1.00123.37 C +ATOM 32595 N THR R 31 42.125 19.525 -9.095 1.00108.96 N +ATOM 32596 CA THR R 31 41.631 18.302 -9.755 1.00134.73 C +ATOM 32597 C THR R 31 40.497 17.645 -8.969 1.00133.54 C +ATOM 32598 O THR R 31 39.677 16.918 -9.531 1.00150.97 O +ATOM 32599 CB THR R 31 42.760 17.261 -10.042 1.00127.92 C +ATOM 32600 OG1 THR R 31 43.504 16.976 -8.854 1.00 96.89 O +ATOM 32601 CG2 THR R 31 43.716 17.777 -11.116 1.00146.42 C +ATOM 32602 N GLY R 32 40.507 17.844 -7.660 1.00144.48 N +ATOM 32603 CA GLY R 32 39.394 17.451 -6.804 1.00157.48 C +ATOM 32604 C GLY R 32 39.463 18.302 -5.554 1.00147.01 C +ATOM 32605 O GLY R 32 40.548 18.738 -5.171 1.00155.17 O +ATOM 32606 N LYS R 33 38.333 18.519 -4.895 1.00121.77 N +ATOM 32607 CA LYS R 33 38.375 19.195 -3.610 1.00114.46 C +ATOM 32608 C LYS R 33 39.127 18.357 -2.554 1.00154.29 C +ATOM 32609 O LYS R 33 39.098 17.126 -2.588 1.00167.09 O +ATOM 32610 CB LYS R 33 36.971 19.564 -3.118 1.00102.46 C +ATOM 32611 CG LYS R 33 36.484 20.902 -3.607 1.00 93.51 C +ATOM 32612 CD LYS R 33 35.032 21.121 -3.228 1.00 83.28 C +ATOM 32613 CE LYS R 33 34.390 22.083 -4.232 1.00 79.06 C +ATOM 32614 NZ LYS R 33 32.936 22.194 -4.028 1.00 95.57 N +ATOM 32615 N ILE R 34 39.761 19.024 -1.585 1.00164.75 N +ATOM 32616 CA ILE R 34 40.582 18.331 -0.571 1.00139.11 C +ATOM 32617 C ILE R 34 39.973 18.420 0.808 1.00129.57 C +ATOM 32618 O ILE R 34 39.657 19.514 1.199 1.00 82.42 O +ATOM 32619 CB ILE R 34 41.970 18.964 -0.462 1.00130.16 C +ATOM 32620 CG1 ILE R 34 42.748 18.683 -1.734 1.00119.79 C +ATOM 32621 CG2 ILE R 34 42.738 18.394 0.715 1.00157.84 C +ATOM 32622 CD1 ILE R 34 43.142 19.940 -2.467 1.00151.75 C +ATOM 32623 N PHE R 35 39.928 17.288 1.532 1.00121.10 N +ATOM 32624 CA PHE R 35 39.166 17.162 2.781 1.00 90.39 C +ATOM 32625 C PHE R 35 39.903 17.768 3.965 1.00 63.86 C +ATOM 32626 O PHE R 35 41.049 17.451 4.118 1.00 60.53 O +ATOM 32627 CB PHE R 35 39.016 15.691 3.105 1.00 74.37 C +ATOM 32628 CG PHE R 35 37.817 15.044 2.506 1.00 86.24 C +ATOM 32629 CD1 PHE R 35 36.560 15.630 2.643 1.00 75.42 C +ATOM 32630 CD2 PHE R 35 37.898 13.740 2.009 1.00 79.10 C +ATOM 32631 CE1 PHE R 35 35.438 14.998 2.113 1.00 72.88 C +ATOM 32632 CE2 PHE R 35 36.773 13.089 1.529 1.00 73.02 C +ATOM 32633 CZ PHE R 35 35.546 13.730 1.551 1.00 74.63 C +ATOM 32634 N VAL R 36 39.279 18.676 4.734 1.00 50.57 N +ATOM 32635 CA VAL R 36 40.007 19.475 5.713 1.00 49.98 C +ATOM 32636 C VAL R 36 39.284 19.603 7.034 1.00 63.35 C +ATOM 32637 O VAL R 36 38.076 19.503 7.099 1.00120.72 O +ATOM 32638 CB VAL R 36 40.293 20.900 5.232 1.00 54.05 C +ATOM 32639 CG1 VAL R 36 39.028 21.785 5.333 1.00 46.22 C +ATOM 32640 CG2 VAL R 36 41.423 21.488 6.035 1.00 68.39 C +ATOM 32641 N SER R 37 40.080 19.682 8.089 1.00 65.65 N +ATOM 32642 CA SER R 37 39.536 19.707 9.442 1.00 80.97 C +ATOM 32643 C SER R 37 40.046 20.964 10.121 1.00 69.54 C +ATOM 32644 O SER R 37 41.229 21.206 10.111 1.00 50.55 O +ATOM 32645 CB SER R 37 40.004 18.479 10.248 1.00 81.02 C +ATOM 32646 OG SER R 37 39.344 17.288 9.877 1.00 64.26 O +ATOM 32647 N VAL R 38 39.149 21.730 10.727 1.00 59.92 N +ATOM 32648 CA VAL R 38 39.569 22.763 11.621 1.00 63.35 C +ATOM 32649 C VAL R 38 38.988 22.499 13.007 1.00 83.10 C +ATOM 32650 O VAL R 38 37.763 22.501 13.180 1.00 77.01 O +ATOM 32651 CB VAL R 38 39.103 24.134 11.153 1.00 65.02 C +ATOM 32652 CG1 VAL R 38 39.549 25.178 12.144 1.00 97.31 C +ATOM 32653 CG2 VAL R 38 39.663 24.463 9.787 1.00 81.16 C +ATOM 32654 N TYR R 39 39.877 22.318 13.997 1.00100.78 N +ATOM 32655 CA TYR R 39 39.487 22.053 15.385 1.00 93.43 C +ATOM 32656 C TYR R 39 39.324 23.387 16.149 1.00 81.72 C +ATOM 32657 O TYR R 39 38.264 23.659 16.722 1.00 75.18 O +ATOM 32658 CB TYR R 39 40.507 21.101 16.070 1.00 92.31 C +ATOM 32659 CG TYR R 39 40.252 19.597 15.819 1.00 99.43 C +ATOM 32660 CD1 TYR R 39 40.539 19.021 14.609 1.00 88.14 C +ATOM 32661 CD2 TYR R 39 39.630 18.793 16.782 1.00111.49 C +ATOM 32662 CE1 TYR R 39 40.195 17.696 14.352 1.00 88.64 C +ATOM 32663 CE2 TYR R 39 39.302 17.467 16.538 1.00 79.99 C +ATOM 32664 CZ TYR R 39 39.560 16.929 15.311 1.00 72.93 C +ATOM 32665 OH TYR R 39 39.356 15.586 15.101 1.00 65.82 O +ATOM 32666 N ASN R 40 40.344 24.234 16.116 1.00 78.34 N +ATOM 32667 CA ASN R 40 40.272 25.509 16.818 1.00 90.87 C +ATOM 32668 C ASN R 40 41.380 26.494 16.450 1.00 96.81 C +ATOM 32669 O ASN R 40 42.565 26.141 16.409 1.00129.74 O +ATOM 32670 CB ASN R 40 40.336 25.258 18.319 1.00114.80 C +ATOM 32671 CG ASN R 40 39.840 26.436 19.126 1.00145.54 C +ATOM 32672 OD1 ASN R 40 40.601 27.056 19.873 1.00140.81 O +ATOM 32673 ND2 ASN R 40 38.564 26.771 18.960 1.00173.94 N +ATOM 32674 N ILE R 41 40.998 27.744 16.215 1.00 92.12 N +ATOM 32675 CA ILE R 41 41.967 28.840 16.084 1.00110.88 C +ATOM 32676 C ILE R 41 41.752 29.858 17.209 1.00112.29 C +ATOM 32677 O ILE R 41 40.682 30.469 17.286 1.00140.58 O +ATOM 32678 CB ILE R 41 41.850 29.555 14.713 1.00 93.33 C +ATOM 32679 CG1 ILE R 41 42.579 28.760 13.621 1.00100.79 C +ATOM 32680 CG2 ILE R 41 42.521 30.916 14.776 1.00 76.88 C +ATOM 32681 CD1 ILE R 41 41.923 27.465 13.207 1.00102.13 C +ATOM 32682 N GLN R 42 42.750 30.023 18.080 1.00102.15 N +ATOM 32683 CA GLN R 42 42.558 30.766 19.336 1.00113.31 C +ATOM 32684 C GLN R 42 42.850 32.240 19.196 1.00113.52 C +ATOM 32685 O GLN R 42 43.602 32.651 18.311 1.00122.62 O +ATOM 32686 CB GLN R 42 43.443 30.220 20.455 1.00116.85 C +ATOM 32687 CG GLN R 42 43.106 28.810 20.880 1.00122.46 C +ATOM 32688 CD GLN R 42 44.271 27.867 20.654 1.00141.20 C +ATOM 32689 OE1 GLN R 42 45.134 27.707 21.522 1.00156.37 O +ATOM 32690 NE2 GLN R 42 44.311 27.238 19.480 1.00151.52 N +ATOM 32691 N ASP R 43 42.264 33.025 20.100 1.00109.96 N +ATOM 32692 CA ASP R 43 42.600 34.443 20.252 1.00115.70 C +ATOM 32693 C ASP R 43 43.876 34.608 21.075 1.00 79.31 C +ATOM 32694 O ASP R 43 43.824 35.121 22.189 1.00 53.68 O +ATOM 32695 CB ASP R 43 41.445 35.195 20.928 1.00127.65 C +ATOM 32696 CG ASP R 43 41.645 36.720 20.921 1.00143.83 C +ATOM 32697 OD1 ASP R 43 41.930 37.277 19.841 1.00129.65 O +ATOM 32698 OD2 ASP R 43 41.489 37.373 21.981 1.00138.63 O +ATOM 32699 N GLU R 44 45.004 34.150 20.519 1.00 65.62 N +ATOM 32700 CA GLU R 44 46.273 34.141 21.234 1.00 68.05 C +ATOM 32701 C GLU R 44 46.831 35.565 21.387 1.00 60.91 C +ATOM 32702 O GLU R 44 47.993 35.751 21.794 1.00 58.79 O +ATOM 32703 CB GLU R 44 47.296 33.220 20.532 1.00 79.90 C +ATOM 32704 CG GLU R 44 47.273 31.743 20.955 1.00 96.70 C +ATOM 32705 CD GLU R 44 48.301 30.849 20.229 1.00129.86 C +ATOM 32706 OE1 GLU R 44 49.485 31.235 20.023 1.00136.07 O +ATOM 32707 OE2 GLU R 44 47.928 29.721 19.816 1.00158.00 O +ATOM 32708 N THR R 45 45.972 36.556 21.167 1.00 64.68 N +ATOM 32709 CA THR R 45 46.395 37.957 21.131 1.00 94.72 C +ATOM 32710 C THR R 45 46.720 38.562 22.501 1.00 86.22 C +ATOM 32711 O THR R 45 47.660 39.324 22.638 1.00 81.68 O +ATOM 32712 CB THR R 45 45.375 38.845 20.370 1.00135.47 C +ATOM 32713 OG1 THR R 45 45.961 40.110 20.067 1.00218.73 O +ATOM 32714 CG2 THR R 45 44.091 39.098 21.162 1.00128.58 C +ATOM 32715 N GLY R 46 45.901 38.272 23.504 1.00 97.68 N +ATOM 32716 CA GLY R 46 46.169 38.705 24.890 1.00 77.53 C +ATOM 32717 C GLY R 46 45.643 40.099 25.210 1.00 62.05 C +ATOM 32718 O GLY R 46 46.009 40.744 26.198 1.00100.37 O +ATOM 32719 N GLN R 47 44.662 40.524 24.475 1.00 59.53 N +ATOM 32720 CA GLN R 47 44.362 41.889 24.517 1.00 74.09 C +ATOM 32721 C GLN R 47 42.879 42.147 24.694 1.00 98.26 C +ATOM 32722 O GLN R 47 42.004 41.454 24.096 1.00127.97 O +ATOM 32723 CB GLN R 47 44.891 42.483 23.253 1.00 91.86 C +ATOM 32724 CG GLN R 47 46.407 42.489 23.189 1.00 85.82 C +ATOM 32725 CD GLN R 47 47.041 43.078 24.411 1.00107.71 C +ATOM 32726 OE1 GLN R 47 46.955 44.278 24.653 1.00144.91 O +ATOM 32727 NE2 GLN R 47 47.658 42.247 25.212 1.00149.58 N +ATOM 32728 N PHE R 48 42.601 43.160 25.507 1.00 73.87 N +ATOM 32729 CA PHE R 48 41.228 43.590 25.758 1.00100.84 C +ATOM 32730 C PHE R 48 41.050 45.060 25.428 1.00 95.03 C +ATOM 32731 O PHE R 48 42.029 45.807 25.312 1.00 72.91 O +ATOM 32732 CB PHE R 48 40.855 43.330 27.226 1.00126.88 C +ATOM 32733 CG PHE R 48 40.794 41.891 27.570 1.00102.65 C +ATOM 32734 CD1 PHE R 48 41.972 41.181 27.743 1.00 74.70 C +ATOM 32735 CD2 PHE R 48 39.570 41.243 27.650 1.00 85.73 C +ATOM 32736 CE1 PHE R 48 41.939 39.844 27.975 1.00 80.62 C +ATOM 32737 CE2 PHE R 48 39.531 39.902 27.883 1.00 94.14 C +ATOM 32738 CZ PHE R 48 40.717 39.202 28.055 1.00107.48 C +ATOM 32739 N LYS R 49 39.785 45.484 25.402 1.00107.98 N +ATOM 32740 CA LYS R 49 39.445 46.864 25.113 1.00114.14 C +ATOM 32741 C LYS R 49 39.709 47.746 26.320 1.00122.98 C +ATOM 32742 O LYS R 49 39.535 47.315 27.471 1.00158.61 O +ATOM 32743 CB LYS R 49 37.988 46.982 24.649 1.00100.57 C +ATOM 32744 CG LYS R 49 37.773 46.257 23.331 1.00104.51 C +ATOM 32745 CD LYS R 49 36.439 46.484 22.649 1.00121.32 C +ATOM 32746 CE LYS R 49 36.527 45.812 21.272 1.00148.96 C +ATOM 32747 NZ LYS R 49 35.319 45.947 20.414 1.00178.99 N +ATOM 32748 N PRO R 50 40.161 48.979 26.060 1.00119.46 N +ATOM 32749 CA PRO R 50 40.406 49.954 27.106 1.00123.85 C +ATOM 32750 C PRO R 50 39.125 50.634 27.615 1.00112.50 C +ATOM 32751 O PRO R 50 38.036 50.494 27.035 1.00 65.46 O +ATOM 32752 CB PRO R 50 41.303 50.986 26.423 1.00144.17 C +ATOM 32753 CG PRO R 50 40.895 50.923 24.992 1.00162.64 C +ATOM 32754 CD PRO R 50 40.505 49.498 24.727 1.00133.09 C +ATOM 32755 N TYR R 51 39.268 51.337 28.733 1.00 92.71 N +ATOM 32756 CA TYR R 51 38.181 52.131 29.257 1.00 69.60 C +ATOM 32757 C TYR R 51 37.626 52.970 28.133 1.00 56.45 C +ATOM 32758 O TYR R 51 38.403 53.580 27.377 1.00 72.58 O +ATOM 32759 CB TYR R 51 38.682 53.024 30.409 1.00 71.96 C +ATOM 32760 CG TYR R 51 37.543 53.619 31.198 1.00 66.50 C +ATOM 32761 CD1 TYR R 51 36.994 52.919 32.260 1.00 77.87 C +ATOM 32762 CD2 TYR R 51 37.018 54.860 30.890 1.00 71.16 C +ATOM 32763 CE1 TYR R 51 35.937 53.418 32.990 1.00 76.41 C +ATOM 32764 CE2 TYR R 51 35.966 55.389 31.635 1.00 88.12 C +ATOM 32765 CZ TYR R 51 35.403 54.627 32.657 1.00 90.41 C +ATOM 32766 OH TYR R 51 34.340 55.074 33.410 1.00 96.93 O +ATOM 32767 N PRO R 52 36.300 53.080 28.051 1.00 54.28 N +ATOM 32768 CA PRO R 52 35.267 52.629 28.992 1.00 65.64 C +ATOM 32769 C PRO R 52 34.680 51.268 28.702 1.00 88.91 C +ATOM 32770 O PRO R 52 33.574 50.971 29.188 1.00 78.56 O +ATOM 32771 CB PRO R 52 34.166 53.681 28.837 1.00 65.10 C +ATOM 32772 CG PRO R 52 34.270 54.079 27.395 1.00 79.96 C +ATOM 32773 CD PRO R 52 35.743 53.987 27.031 1.00 69.03 C +ATOM 32774 N ALA R 53 35.361 50.441 27.900 1.00111.50 N +ATOM 32775 CA ALA R 53 34.830 49.102 27.604 1.00125.60 C +ATOM 32776 C ALA R 53 34.743 48.311 28.899 1.00107.02 C +ATOM 32777 O ALA R 53 35.473 48.608 29.864 1.00109.33 O +ATOM 32778 CB ALA R 53 35.683 48.365 26.556 1.00124.59 C +ATOM 32779 N SER R 54 33.895 47.287 28.915 1.00 77.65 N +ATOM 32780 CA SER R 54 34.009 46.322 29.986 1.00 65.54 C +ATOM 32781 C SER R 54 35.421 45.731 30.029 1.00 72.04 C +ATOM 32782 O SER R 54 36.115 45.511 28.991 1.00 78.92 O +ATOM 32783 CB SER R 54 33.033 45.197 29.828 1.00 73.48 C +ATOM 32784 OG SER R 54 33.425 44.032 30.570 1.00 60.88 O +ATOM 32785 N ASN R 55 35.871 45.498 31.255 1.00 61.87 N +ATOM 32786 CA ASN R 55 37.165 44.897 31.489 1.00 53.53 C +ATOM 32787 C ASN R 55 37.362 43.658 30.611 1.00 54.75 C +ATOM 32788 O ASN R 55 38.492 43.273 30.254 1.00 39.20 O +ATOM 32789 CB ASN R 55 37.260 44.541 32.962 1.00 44.15 C +ATOM 32790 CG ASN R 55 38.656 44.184 33.355 1.00 76.29 C +ATOM 32791 OD1 ASN R 55 39.651 44.602 32.735 1.00120.59 O +ATOM 32792 ND2 ASN R 55 38.759 43.484 34.441 1.00101.45 N +ATOM 32793 N PHE R 56 36.231 43.000 30.332 1.00 63.86 N +ATOM 32794 CA PHE R 56 36.204 41.648 29.773 1.00 62.80 C +ATOM 32795 C PHE R 56 35.965 41.636 28.289 1.00 64.50 C +ATOM 32796 O PHE R 56 35.939 40.575 27.675 1.00 83.54 O +ATOM 32797 CB PHE R 56 35.078 40.817 30.388 1.00 47.41 C +ATOM 32798 CG PHE R 56 35.186 40.651 31.872 1.00 37.12 C +ATOM 32799 CD1 PHE R 56 36.288 40.039 32.468 1.00 33.64 C +ATOM 32800 CD2 PHE R 56 34.206 41.100 32.652 1.00 39.78 C +ATOM 32801 CE1 PHE R 56 36.382 39.889 33.824 1.00 32.02 C +ATOM 32802 CE2 PHE R 56 34.283 40.935 34.028 1.00 46.91 C +ATOM 32803 CZ PHE R 56 35.384 40.351 34.613 1.00 35.89 C +ATOM 32804 N SER R 57 35.757 42.793 27.711 1.00 60.15 N +ATOM 32805 CA SER R 57 35.624 42.841 26.272 1.00 65.30 C +ATOM 32806 C SER R 57 37.003 42.612 25.559 1.00 74.63 C +ATOM 32807 O SER R 57 37.952 43.386 25.671 1.00 59.67 O +ATOM 32808 CB SER R 57 35.003 44.172 25.874 1.00 76.38 C +ATOM 32809 OG SER R 57 33.636 44.206 26.278 1.00 46.80 O +ATOM 32810 N THR R 58 37.097 41.524 24.827 1.00 84.15 N +ATOM 32811 CA THR R 58 38.314 41.208 24.108 1.00 95.50 C +ATOM 32812 C THR R 58 38.521 42.157 22.968 1.00 90.03 C +ATOM 32813 O THR R 58 37.573 42.620 22.341 1.00104.14 O +ATOM 32814 CB THR R 58 38.233 39.789 23.530 1.00117.89 C +ATOM 32815 OG1 THR R 58 37.125 39.681 22.622 1.00 97.77 O +ATOM 32816 CG2 THR R 58 38.011 38.810 24.643 1.00148.13 C +ATOM 32817 N ALA R 59 39.754 42.309 22.560 1.00 93.60 N +ATOM 32818 CA ALA R 59 39.994 43.229 21.477 1.00118.17 C +ATOM 32819 C ALA R 59 39.677 42.610 20.132 1.00115.33 C +ATOM 32820 O ALA R 59 39.414 43.325 19.151 1.00172.85 O +ATOM 32821 CB ALA R 59 41.420 43.689 21.490 1.00128.27 C +ATOM 32822 N VAL R 60 39.625 41.282 20.095 1.00 97.78 N +ATOM 32823 CA VAL R 60 39.424 40.538 18.842 1.00 90.68 C +ATOM 32824 C VAL R 60 38.331 39.492 19.028 1.00105.99 C +ATOM 32825 O VAL R 60 38.236 38.881 20.092 1.00182.99 O +ATOM 32826 CB VAL R 60 40.724 39.825 18.464 1.00 72.89 C +ATOM 32827 CG1 VAL R 60 40.569 39.029 17.196 1.00 56.78 C +ATOM 32828 CG2 VAL R 60 41.844 40.847 18.346 1.00 97.90 C +ATOM 32829 N PRO R 61 37.446 39.336 18.030 1.00117.63 N +ATOM 32830 CA PRO R 61 36.397 38.345 18.197 1.00133.24 C +ATOM 32831 C PRO R 61 36.967 36.923 18.329 1.00140.21 C +ATOM 32832 O PRO R 61 37.947 36.579 17.658 1.00143.30 O +ATOM 32833 CB PRO R 61 35.557 38.503 16.923 1.00121.31 C +ATOM 32834 CG PRO R 61 36.462 39.157 15.942 1.00 99.98 C +ATOM 32835 CD PRO R 61 37.319 40.057 16.757 1.00102.82 C +ATOM 32836 N GLN R 62 36.296 36.100 19.136 1.00117.22 N +ATOM 32837 CA GLN R 62 36.752 34.744 19.409 1.00115.36 C +ATOM 32838 C GLN R 62 36.292 33.738 18.367 1.00124.90 C +ATOM 32839 O GLN R 62 35.929 32.622 18.702 1.00101.72 O +ATOM 32840 CB GLN R 62 36.241 34.314 20.791 1.00128.82 C +ATOM 32841 CG GLN R 62 36.522 35.310 21.898 1.00128.55 C +ATOM 32842 CD GLN R 62 38.006 35.589 22.017 1.00127.58 C +ATOM 32843 OE1 GLN R 62 38.751 34.804 22.593 1.00150.15 O +ATOM 32844 NE2 GLN R 62 38.443 36.693 21.460 1.00146.76 N +ATOM 32845 N SER R 63 36.187 34.178 17.120 1.00145.25 N +ATOM 32846 CA SER R 63 35.330 33.508 16.135 1.00149.30 C +ATOM 32847 C SER R 63 36.141 33.058 14.927 1.00127.85 C +ATOM 32848 O SER R 63 35.583 32.628 13.916 1.00112.63 O +ATOM 32849 CB SER R 63 34.155 34.431 15.707 1.00141.86 C +ATOM 32850 OG SER R 63 34.580 35.638 15.081 1.00110.53 O +ATOM 32851 N ALA R 64 37.457 33.187 15.048 1.00 99.14 N +ATOM 32852 CA ALA R 64 38.371 32.953 13.940 1.00 86.58 C +ATOM 32853 C ALA R 64 38.222 31.565 13.315 1.00 88.13 C +ATOM 32854 O ALA R 64 38.257 31.412 12.087 1.00129.98 O +ATOM 32855 CB ALA R 64 39.781 33.143 14.425 1.00 94.90 C +ATOM 32856 N THR R 65 37.942 30.579 14.156 1.00 99.59 N +ATOM 32857 CA THR R 65 37.747 29.204 13.727 1.00100.35 C +ATOM 32858 C THR R 65 36.682 29.061 12.654 1.00102.87 C +ATOM 32859 O THR R 65 36.919 28.453 11.593 1.00126.99 O +ATOM 32860 CB THR R 65 37.276 28.359 14.904 1.00121.55 C +ATOM 32861 OG1 THR R 65 37.976 28.779 16.077 1.00159.68 O +ATOM 32862 CG2 THR R 65 37.522 26.872 14.637 1.00138.74 C +ATOM 32863 N ALA R 66 35.519 29.651 12.907 1.00 79.25 N +ATOM 32864 CA ALA R 66 34.425 29.540 11.969 1.00 87.92 C +ATOM 32865 C ALA R 66 34.701 30.322 10.674 1.00 84.56 C +ATOM 32866 O ALA R 66 34.307 29.903 9.564 1.00 86.40 O +ATOM 32867 CB ALA R 66 33.149 30.019 12.622 1.00113.26 C +ATOM 32868 N MET R 67 35.396 31.450 10.810 1.00 82.42 N +ATOM 32869 CA MET R 67 35.807 32.251 9.641 1.00102.86 C +ATOM 32870 C MET R 67 36.751 31.461 8.717 1.00 80.06 C +ATOM 32871 O MET R 67 36.610 31.498 7.495 1.00 63.05 O +ATOM 32872 CB MET R 67 36.503 33.561 10.074 1.00115.93 C +ATOM 32873 CG MET R 67 35.601 34.596 10.740 1.00124.82 C +ATOM 32874 SD MET R 67 36.569 35.920 11.510 1.00113.09 S +ATOM 32875 CE MET R 67 35.269 37.044 12.039 1.00113.62 C +ATOM 32876 N LEU R 68 37.704 30.761 9.321 1.00 77.90 N +ATOM 32877 CA LEU R 68 38.634 29.962 8.568 1.00 78.24 C +ATOM 32878 C LEU R 68 37.923 28.842 7.848 1.00 88.36 C +ATOM 32879 O LEU R 68 38.181 28.609 6.679 1.00 79.65 O +ATOM 32880 CB LEU R 68 39.697 29.355 9.468 1.00100.35 C +ATOM 32881 CG LEU R 68 40.572 28.312 8.741 1.00121.93 C +ATOM 32882 CD1 LEU R 68 41.400 28.982 7.655 1.00141.57 C +ATOM 32883 CD2 LEU R 68 41.478 27.549 9.692 1.00112.26 C +ATOM 32884 N VAL R 69 37.026 28.136 8.542 1.00127.31 N +ATOM 32885 CA VAL R 69 36.255 27.052 7.905 1.00127.56 C +ATOM 32886 C VAL R 69 35.460 27.593 6.709 1.00124.86 C +ATOM 32887 O VAL R 69 35.439 27.001 5.625 1.00111.79 O +ATOM 32888 CB VAL R 69 35.273 26.354 8.879 1.00120.15 C +ATOM 32889 CG1 VAL R 69 34.428 25.356 8.121 1.00102.90 C +ATOM 32890 CG2 VAL R 69 36.005 25.644 10.010 1.00107.60 C +ATOM 32891 N THR R 70 34.830 28.746 6.912 1.00116.36 N +ATOM 32892 CA THR R 70 34.059 29.395 5.863 1.00105.28 C +ATOM 32893 C THR R 70 34.938 29.790 4.677 1.00 91.65 C +ATOM 32894 O THR R 70 34.584 29.546 3.509 1.00110.32 O +ATOM 32895 CB THR R 70 33.322 30.628 6.406 1.00 92.70 C +ATOM 32896 OG1 THR R 70 32.520 30.217 7.524 1.00 80.53 O +ATOM 32897 CG2 THR R 70 32.427 31.257 5.315 1.00 96.46 C +ATOM 32898 N ALA R 71 36.087 30.373 4.971 1.00 79.81 N +ATOM 32899 CA ALA R 71 37.020 30.725 3.906 1.00112.76 C +ATOM 32900 C ALA R 71 37.488 29.482 3.136 1.00103.52 C +ATOM 32901 O ALA R 71 37.617 29.506 1.902 1.00 94.32 O +ATOM 32902 CB ALA R 71 38.214 31.490 4.479 1.00124.39 C +ATOM 32903 N LEU R 72 37.771 28.417 3.876 1.00107.05 N +ATOM 32904 CA LEU R 72 38.209 27.154 3.268 1.00118.25 C +ATOM 32905 C LEU R 72 37.132 26.577 2.368 1.00105.45 C +ATOM 32906 O LEU R 72 37.445 25.890 1.404 1.00104.91 O +ATOM 32907 CB LEU R 72 38.567 26.113 4.340 1.00101.74 C +ATOM 32908 CG LEU R 72 39.814 26.415 5.167 1.00 86.60 C +ATOM 32909 CD1 LEU R 72 39.799 25.579 6.398 1.00 65.81 C +ATOM 32910 CD2 LEU R 72 41.081 26.170 4.377 1.00112.03 C +ATOM 32911 N LYS R 73 35.881 26.923 2.642 1.00 85.60 N +ATOM 32912 CA LYS R 73 34.805 26.452 1.798 1.00 96.29 C +ATOM 32913 C LYS R 73 34.678 27.350 0.562 1.00102.24 C +ATOM 32914 O LYS R 73 34.444 26.856 -0.544 1.00137.24 O +ATOM 32915 CB LYS R 73 33.464 26.389 2.545 1.00108.43 C +ATOM 32916 CG LYS R 73 32.367 25.613 1.790 1.00101.09 C +ATOM 32917 CD LYS R 73 31.042 25.546 2.565 1.00 95.27 C +ATOM 32918 CE LYS R 73 29.849 25.393 1.632 1.00 79.21 C +ATOM 32919 NZ LYS R 73 29.180 24.070 1.747 1.00 60.84 N +ATOM 32920 N ASP R 74 34.673 28.665 0.770 1.00101.15 N +ATOM 32921 CA ASP R 74 34.365 29.615 -0.312 1.00106.01 C +ATOM 32922 C ASP R 74 35.386 29.460 -1.428 1.00 93.42 C +ATOM 32923 O ASP R 74 35.088 29.761 -2.590 1.00117.75 O +ATOM 32924 CB ASP R 74 34.340 31.067 0.210 1.00 95.07 C +ATOM 32925 CG ASP R 74 33.122 31.379 1.097 1.00 76.88 C +ATOM 32926 OD1 ASP R 74 32.045 30.739 0.958 1.00 41.34 O +ATOM 32927 OD2 ASP R 74 33.287 32.235 1.997 1.00 78.57 O +ATOM 32928 N SER R 75 36.581 28.997 -1.067 1.00 83.81 N +ATOM 32929 CA SER R 75 37.686 28.889 -2.026 1.00124.94 C +ATOM 32930 C SER R 75 37.424 27.858 -3.113 1.00124.78 C +ATOM 32931 O SER R 75 37.997 27.926 -4.202 1.00108.85 O +ATOM 32932 CB SER R 75 38.985 28.524 -1.307 1.00145.34 C +ATOM 32933 OG SER R 75 39.094 27.124 -1.123 1.00131.26 O +ATOM 32934 N ARG R 76 36.553 26.911 -2.792 1.00126.57 N +ATOM 32935 CA ARG R 76 36.220 25.808 -3.676 1.00142.57 C +ATOM 32936 C ARG R 76 37.451 24.978 -3.973 1.00114.72 C +ATOM 32937 O ARG R 76 37.587 24.414 -5.055 1.00 90.04 O +ATOM 32938 CB ARG R 76 35.587 26.302 -4.971 1.00156.89 C +ATOM 32939 CG ARG R 76 34.284 27.075 -4.785 1.00130.25 C +ATOM 32940 CD ARG R 76 33.738 27.484 -6.139 1.00147.79 C +ATOM 32941 NE ARG R 76 34.592 28.508 -6.755 1.00153.84 N +ATOM 32942 CZ ARG R 76 35.567 28.273 -7.641 1.00156.87 C +ATOM 32943 NH1 ARG R 76 35.859 27.027 -8.040 1.00159.99 N +ATOM 32944 NH2 ARG R 76 36.264 29.294 -8.119 1.00124.71 N +ATOM 32945 N TRP R 77 38.295 24.848 -2.957 1.00128.41 N +ATOM 32946 CA TRP R 77 39.397 23.885 -2.948 1.00148.99 C +ATOM 32947 C TRP R 77 39.216 22.777 -1.861 1.00146.12 C +ATOM 32948 O TRP R 77 39.591 21.614 -2.076 1.00 95.50 O +ATOM 32949 CB TRP R 77 40.696 24.640 -2.677 1.00141.75 C +ATOM 32950 CG TRP R 77 41.398 25.133 -3.859 1.00108.15 C +ATOM 32951 CD1 TRP R 77 41.064 26.203 -4.619 1.00 94.11 C +ATOM 32952 CD2 TRP R 77 42.573 24.564 -4.439 1.00 93.48 C +ATOM 32953 NE1 TRP R 77 41.945 26.321 -5.654 1.00124.34 N +ATOM 32954 CE2 TRP R 77 42.897 25.338 -5.549 1.00 98.38 C +ATOM 32955 CE3 TRP R 77 43.384 23.471 -4.122 1.00100.26 C +ATOM 32956 CZ2 TRP R 77 43.999 25.057 -6.362 1.00104.01 C +ATOM 32957 CZ3 TRP R 77 44.476 23.191 -4.931 1.00100.08 C +ATOM 32958 CH2 TRP R 77 44.772 23.981 -6.034 1.00101.08 C +ATOM 32959 N PHE R 78 38.531 23.118 -0.774 1.00143.58 N +ATOM 32960 CA PHE R 78 38.362 22.226 0.376 1.00131.20 C +ATOM 32961 C PHE R 78 36.883 22.005 0.619 1.00143.65 C +ATOM 32962 O PHE R 78 36.111 22.904 0.671 1.00138.95 O +ATOM 32963 CB PHE R 78 39.032 22.878 1.584 1.00132.88 C +ATOM 32964 CG PHE R 78 40.479 23.257 1.342 1.00120.83 C +ATOM 32965 CD1 PHE R 78 41.485 22.276 1.299 1.00 92.52 C +ATOM 32966 CD2 PHE R 78 40.837 24.602 1.188 1.00 94.48 C +ATOM 32967 CE1 PHE R 78 42.807 22.639 1.159 1.00 81.88 C +ATOM 32968 CE2 PHE R 78 42.164 24.972 1.046 1.00 80.89 C +ATOM 32969 CZ PHE R 78 43.146 23.984 1.017 1.00 91.23 C +ATOM 32970 N ILE R 79 36.491 20.756 0.648 1.00151.66 N +ATOM 32971 CA ILE R 79 35.344 20.430 1.503 1.00132.50 C +ATOM 32972 C ILE R 79 35.949 20.618 2.821 1.00135.42 C +ATOM 32973 O ILE R 79 36.986 20.017 3.075 1.00114.71 O +ATOM 32974 CB ILE R 79 34.952 18.949 1.399 1.00113.55 C +ATOM 32975 CG1 ILE R 79 34.824 18.643 -0.101 1.00150.73 C +ATOM 32976 CG2 ILE R 79 33.669 18.700 2.162 1.00115.05 C +ATOM 32977 CD1 ILE R 79 34.960 17.213 -0.468 1.00137.00 C +ATOM 32978 N PRO R 80 35.320 21.447 3.691 1.00170.42 N +ATOM 32979 CA PRO R 80 35.832 21.386 5.036 1.00156.63 C +ATOM 32980 C PRO R 80 35.098 20.432 5.806 1.00124.14 C +ATOM 32981 O PRO R 80 33.903 20.630 6.198 1.00111.09 O +ATOM 32982 CB PRO R 80 35.442 22.685 5.675 1.00160.42 C +ATOM 32983 CG PRO R 80 35.245 23.591 4.480 1.00218.24 C +ATOM 32984 CD PRO R 80 34.554 22.677 3.537 1.00215.30 C +ATOM 32985 N LEU R 81 35.818 19.394 6.097 1.00106.84 N +ATOM 32986 CA LEU R 81 35.325 18.605 7.199 1.00 93.42 C +ATOM 32987 C LEU R 81 35.455 19.282 8.527 1.00 86.87 C +ATOM 32988 O LEU R 81 36.572 19.729 8.944 1.00 79.68 O +ATOM 32989 CB LEU R 81 35.996 17.257 7.290 1.00119.76 C +ATOM 32990 CG LEU R 81 35.568 16.160 6.271 1.00140.43 C +ATOM 32991 CD1 LEU R 81 36.383 14.906 6.532 1.00 98.97 C +ATOM 32992 CD2 LEU R 81 34.068 15.928 6.410 1.00174.83 C +ATOM 32993 N GLU R 82 34.267 19.146 9.195 1.00 92.84 N +ATOM 32994 CA GLU R 82 33.687 19.633 10.540 1.00123.67 C +ATOM 32995 C GLU R 82 33.976 18.775 11.827 1.00107.03 C +ATOM 32996 O GLU R 82 33.604 17.596 11.860 1.00 88.14 O +ATOM 32997 CB GLU R 82 32.112 19.729 10.457 1.00114.41 C +ATOM 32998 CG GLU R 82 31.392 20.174 11.760 1.00127.58 C +ATOM 32999 CD GLU R 82 31.608 21.650 12.173 1.00117.09 C +ATOM 33000 OE1 GLU R 82 32.729 22.183 12.134 1.00125.23 O +ATOM 33001 OE2 GLU R 82 30.635 22.301 12.598 1.00 64.15 O +ATOM 33002 N ARG R 83 34.429 19.511 12.873 1.00104.92 N +ATOM 33003 CA ARG R 83 35.000 19.107 14.200 1.00 97.86 C +ATOM 33004 C ARG R 83 34.792 20.158 15.356 1.00 87.97 C +ATOM 33005 O ARG R 83 34.953 19.825 16.551 1.00102.07 O +ATOM 33006 CB ARG R 83 36.513 18.858 14.011 1.00103.39 C +ATOM 33007 CG ARG R 83 36.792 17.861 12.920 1.00 87.70 C +ATOM 33008 CD ARG R 83 36.385 16.480 13.324 1.00 92.41 C +ATOM 33009 NE ARG R 83 36.880 15.570 12.307 1.00 97.03 N +ATOM 33010 CZ ARG R 83 36.152 15.010 11.332 1.00119.96 C +ATOM 33011 NH1 ARG R 83 34.834 15.193 11.228 1.00 91.21 N +ATOM 33012 NH2 ARG R 83 36.769 14.199 10.469 1.00162.73 N +ATOM 33013 N GLN R 84 34.448 21.413 15.048 1.00 82.32 N +ATOM 33014 CA GLN R 84 34.253 22.411 16.130 1.00 99.97 C +ATOM 33015 C GLN R 84 33.139 21.973 17.059 1.00 96.04 C +ATOM 33016 O GLN R 84 33.276 22.034 18.262 1.00122.06 O +ATOM 33017 CB GLN R 84 33.984 23.838 15.616 1.00 84.90 C +ATOM 33018 CG GLN R 84 34.496 24.965 16.523 1.00 66.64 C +ATOM 33019 CD GLN R 84 34.118 26.332 16.010 1.00 73.10 C +ATOM 33020 OE1 GLN R 84 34.113 26.591 14.796 1.00101.61 O +ATOM 33021 NE2 GLN R 84 33.821 27.234 16.920 1.00 96.64 N +ATOM 33022 N GLY R 85 32.093 21.388 16.519 1.00132.90 N +ATOM 33023 CA GLY R 85 31.040 20.856 17.391 1.00150.90 C +ATOM 33024 C GLY R 85 30.964 19.343 17.424 1.00138.64 C +ATOM 33025 O GLY R 85 29.868 18.788 17.405 1.00142.41 O +ATOM 33026 N LEU R 86 32.118 18.664 17.451 1.00110.22 N +ATOM 33027 CA LEU R 86 32.167 17.205 17.176 1.00 84.93 C +ATOM 33028 C LEU R 86 31.340 16.413 18.181 1.00 88.73 C +ATOM 33029 O LEU R 86 30.690 15.427 17.827 1.00 70.89 O +ATOM 33030 CB LEU R 86 33.598 16.672 17.201 1.00 79.01 C +ATOM 33031 CG LEU R 86 33.870 15.143 17.146 1.00 60.41 C +ATOM 33032 CD1 LEU R 86 33.346 14.516 15.881 1.00 56.39 C +ATOM 33033 CD2 LEU R 86 35.363 14.895 17.245 1.00 66.84 C +ATOM 33034 N GLN R 87 31.301 16.899 19.413 1.00 96.09 N +ATOM 33035 CA GLN R 87 30.583 16.186 20.461 1.00105.70 C +ATOM 33036 C GLN R 87 29.068 16.025 20.143 1.00108.31 C +ATOM 33037 O GLN R 87 28.478 14.947 20.323 1.00143.79 O +ATOM 33038 CB GLN R 87 30.811 16.886 21.805 1.00109.91 C +ATOM 33039 CG GLN R 87 30.886 15.928 22.980 1.00118.10 C +ATOM 33040 CD GLN R 87 31.704 14.672 22.677 1.00137.66 C +ATOM 33041 OE1 GLN R 87 32.891 14.748 22.341 1.00156.10 O +ATOM 33042 NE2 GLN R 87 31.089 13.505 22.857 1.00150.77 N +ATOM 33043 N ASN R 88 28.440 17.103 19.676 1.00 79.40 N +ATOM 33044 CA ASN R 88 27.023 17.084 19.348 1.00 49.16 C +ATOM 33045 C ASN R 88 26.802 16.136 18.208 1.00 47.77 C +ATOM 33046 O ASN R 88 25.729 15.531 18.063 1.00 63.18 O +ATOM 33047 CB ASN R 88 26.559 18.466 18.924 1.00 62.38 C +ATOM 33048 CG ASN R 88 26.741 19.488 19.988 1.00 74.91 C +ATOM 33049 OD1 ASN R 88 26.651 19.158 21.169 1.00 73.92 O +ATOM 33050 ND2 ASN R 88 27.142 20.721 19.592 1.00 84.89 N +ATOM 33051 N LEU R 89 27.765 16.089 17.298 1.00 59.41 N +ATOM 33052 CA LEU R 89 27.618 15.316 16.063 1.00 95.79 C +ATOM 33053 C LEU R 89 27.553 13.834 16.470 1.00 99.23 C +ATOM 33054 O LEU R 89 26.695 13.065 15.994 1.00 79.88 O +ATOM 33055 CB LEU R 89 28.811 15.606 15.125 1.00 96.67 C +ATOM 33056 CG LEU R 89 28.662 15.468 13.609 1.00 84.91 C +ATOM 33057 CD1 LEU R 89 29.526 14.327 13.122 1.00 81.84 C +ATOM 33058 CD2 LEU R 89 27.219 15.220 13.200 1.00 88.74 C +ATOM 33059 N LEU R 90 28.407 13.482 17.420 1.00 85.41 N +ATOM 33060 CA LEU R 90 28.471 12.106 17.893 1.00 89.03 C +ATOM 33061 C LEU R 90 27.208 11.743 18.698 1.00 96.70 C +ATOM 33062 O LEU R 90 26.773 10.594 18.710 1.00 99.06 O +ATOM 33063 CB LEU R 90 29.720 11.917 18.745 1.00 83.91 C +ATOM 33064 CG LEU R 90 31.027 12.195 18.037 1.00 73.95 C +ATOM 33065 CD1 LEU R 90 32.134 12.438 19.038 1.00 66.96 C +ATOM 33066 CD2 LEU R 90 31.333 11.021 17.126 1.00 93.25 C +ATOM 33067 N ASN R 91 26.633 12.740 19.369 1.00 77.82 N +ATOM 33068 CA ASN R 91 25.407 12.554 20.109 1.00 63.26 C +ATOM 33069 C ASN R 91 24.224 12.295 19.226 1.00 69.80 C +ATOM 33070 O ASN R 91 23.477 11.354 19.453 1.00 93.88 O +ATOM 33071 CB ASN R 91 25.128 13.749 20.976 1.00 85.88 C +ATOM 33072 CG ASN R 91 24.872 13.319 22.394 1.00130.56 C +ATOM 33073 OD1 ASN R 91 25.735 12.653 22.974 1.00185.39 O +ATOM 33074 ND2 ASN R 91 23.664 13.569 22.924 1.00132.28 N +ATOM 33075 N GLU R 92 24.057 13.116 18.186 1.00 96.90 N +ATOM 33076 CA GLU R 92 22.983 12.902 17.200 1.00 90.66 C +ATOM 33077 C GLU R 92 23.104 11.530 16.538 1.00 80.71 C +ATOM 33078 O GLU R 92 22.096 10.831 16.313 1.00 52.57 O +ATOM 33079 CB GLU R 92 22.979 13.976 16.113 1.00 70.93 C +ATOM 33080 CG GLU R 92 22.118 15.184 16.420 1.00 61.51 C +ATOM 33081 CD GLU R 92 20.689 14.827 16.824 1.00 78.00 C +ATOM 33082 OE1 GLU R 92 19.939 14.134 16.022 1.00 96.30 O +ATOM 33083 OE2 GLU R 92 20.309 15.239 17.964 1.00 68.44 O +ATOM 33084 N ARG R 93 24.342 11.114 16.307 1.00 66.45 N +ATOM 33085 CA ARG R 93 24.570 9.782 15.797 1.00 85.41 C +ATOM 33086 C ARG R 93 24.200 8.663 16.826 1.00 83.52 C +ATOM 33087 O ARG R 93 23.710 7.587 16.449 1.00 57.66 O +ATOM 33088 CB ARG R 93 26.008 9.677 15.276 1.00 85.38 C +ATOM 33089 CG ARG R 93 26.225 10.543 14.049 1.00 71.56 C +ATOM 33090 CD ARG R 93 27.691 10.770 13.710 1.00 81.83 C +ATOM 33091 NE ARG R 93 28.149 9.935 12.605 1.00 76.89 N +ATOM 33092 CZ ARG R 93 28.797 8.790 12.742 1.00 94.72 C +ATOM 33093 NH1 ARG R 93 29.089 8.292 13.944 1.00124.00 N +ATOM 33094 NH2 ARG R 93 29.174 8.137 11.664 1.00119.28 N +ATOM 33095 N LYS R 94 24.403 8.919 18.115 1.00 76.53 N +ATOM 33096 CA LYS R 94 23.960 7.969 19.140 1.00 81.88 C +ATOM 33097 C LYS R 94 22.440 7.838 19.099 1.00 70.57 C +ATOM 33098 O LYS R 94 21.898 6.738 19.247 1.00 49.09 O +ATOM 33099 CB LYS R 94 24.376 8.435 20.532 1.00100.35 C +ATOM 33100 CG LYS R 94 25.755 7.985 21.000 1.00115.05 C +ATOM 33101 CD LYS R 94 26.107 8.684 22.309 1.00125.22 C +ATOM 33102 CE LYS R 94 27.195 7.971 23.095 1.00127.37 C +ATOM 33103 NZ LYS R 94 27.725 8.867 24.160 1.00137.82 N +ATOM 33104 N ILE R 95 21.764 8.977 18.900 1.00 69.50 N +ATOM 33105 CA ILE R 95 20.305 9.016 18.961 1.00 66.94 C +ATOM 33106 C ILE R 95 19.711 8.325 17.746 1.00 87.66 C +ATOM 33107 O ILE R 95 18.710 7.561 17.881 1.00 80.43 O +ATOM 33108 CB ILE R 95 19.709 10.427 19.030 1.00 49.44 C +ATOM 33109 CG1 ILE R 95 20.379 11.246 20.109 1.00 70.54 C +ATOM 33110 CG2 ILE R 95 18.252 10.296 19.395 1.00 54.62 C +ATOM 33111 CD1 ILE R 95 19.660 12.514 20.498 1.00 79.96 C +ATOM 33112 N ILE R 96 20.351 8.570 16.595 1.00 76.82 N +ATOM 33113 CA ILE R 96 20.058 7.823 15.390 1.00 74.65 C +ATOM 33114 C ILE R 96 20.180 6.322 15.635 1.00 87.65 C +ATOM 33115 O ILE R 96 19.201 5.578 15.461 1.00135.96 O +ATOM 33116 CB ILE R 96 20.972 8.204 14.218 1.00 58.34 C +ATOM 33117 CG1 ILE R 96 20.709 9.639 13.829 1.00 69.60 C +ATOM 33118 CG2 ILE R 96 20.682 7.310 13.013 1.00 50.87 C +ATOM 33119 CD1 ILE R 96 21.509 10.074 12.623 1.00100.30 C +ATOM 33120 N ARG R 97 21.367 5.877 16.029 1.00 71.05 N +ATOM 33121 CA ARG R 97 21.616 4.455 16.181 1.00 78.27 C +ATOM 33122 C ARG R 97 20.663 3.836 17.202 1.00 79.89 C +ATOM 33123 O ARG R 97 20.316 2.633 17.101 1.00103.28 O +ATOM 33124 CB ARG R 97 23.065 4.186 16.588 1.00 90.41 C +ATOM 33125 CG ARG R 97 23.954 3.680 15.462 1.00103.95 C +ATOM 33126 CD ARG R 97 25.358 3.376 15.973 1.00111.25 C +ATOM 33127 NE ARG R 97 26.173 4.581 16.092 1.00 93.38 N +ATOM 33128 CZ ARG R 97 27.050 4.984 15.172 1.00107.86 C +ATOM 33129 NH1 ARG R 97 27.262 4.289 14.038 1.00102.98 N +ATOM 33130 NH2 ARG R 97 27.728 6.100 15.380 1.00121.56 N +ATOM 33131 N ALA R 98 20.277 4.617 18.210 1.00 53.49 N +ATOM 33132 CA ALA R 98 19.362 4.112 19.207 1.00 59.41 C +ATOM 33133 C ALA R 98 17.944 3.990 18.648 1.00 76.40 C +ATOM 33134 O ALA R 98 17.138 3.132 19.084 1.00 74.49 O +ATOM 33135 CB ALA R 98 19.384 5.004 20.411 1.00 51.38 C +ATOM 33136 N ALA R 99 17.655 4.843 17.671 1.00 87.19 N +ATOM 33137 CA ALA R 99 16.345 4.867 17.042 1.00 90.22 C +ATOM 33138 C ALA R 99 16.096 3.600 16.221 1.00 63.28 C +ATOM 33139 O ALA R 99 15.049 2.972 16.320 1.00 38.74 O +ATOM 33140 CB ALA R 99 16.194 6.130 16.177 1.00 94.56 C +ATOM 33141 N GLN R 100 17.054 3.282 15.364 1.00 69.30 N +ATOM 33142 CA GLN R 100 16.797 2.380 14.238 1.00 99.67 C +ATOM 33143 C GLN R 100 17.468 1.029 14.402 1.00 87.68 C +ATOM 33144 O GLN R 100 17.406 0.183 13.500 1.00 91.91 O +ATOM 33145 CB GLN R 100 17.220 3.008 12.891 1.00111.82 C +ATOM 33146 CG GLN R 100 18.550 3.746 12.909 1.00108.05 C +ATOM 33147 CD GLN R 100 18.656 4.865 11.877 1.00 98.81 C +ATOM 33148 OE1 GLN R 100 17.855 5.823 11.853 1.00 57.77 O +ATOM 33149 NE2 GLN R 100 19.658 4.744 11.019 1.00 97.38 N +ATOM 33150 N GLU R 101 18.048 0.801 15.570 1.00 82.17 N +ATOM 33151 CA GLU R 101 18.691 -0.487 15.847 1.00104.96 C +ATOM 33152 C GLU R 101 17.729 -1.700 15.865 1.00 92.22 C +ATOM 33153 O GLU R 101 18.154 -2.827 15.664 1.00 84.43 O +ATOM 33154 CB GLU R 101 19.495 -0.408 17.153 1.00112.40 C +ATOM 33155 CG GLU R 101 18.704 0.073 18.362 1.00117.46 C +ATOM 33156 CD GLU R 101 19.526 0.060 19.643 1.00120.86 C +ATOM 33157 OE1 GLU R 101 20.773 0.005 19.544 1.00125.74 O +ATOM 33158 OE2 GLU R 101 18.933 0.118 20.745 1.00 98.12 O +ATOM 33159 N ASN R 102 16.450 -1.462 16.124 1.00 76.04 N +ATOM 33160 CA ASN R 102 15.505 -2.546 16.261 1.00 59.04 C +ATOM 33161 C ASN R 102 14.827 -2.879 14.961 1.00 67.24 C +ATOM 33162 O ASN R 102 13.949 -3.747 14.914 1.00 96.00 O +ATOM 33163 CB ASN R 102 14.484 -2.214 17.349 1.00 53.04 C +ATOM 33164 CG ASN R 102 15.090 -2.306 18.712 1.00 73.92 C +ATOM 33165 OD1 ASN R 102 15.291 -3.401 19.267 1.00 91.53 O +ATOM 33166 ND2 ASN R 102 15.455 -1.153 19.259 1.00117.86 N +ATOM 33167 N GLY R 103 15.113 -2.112 13.920 1.00 75.30 N +ATOM 33168 CA GLY R 103 14.376 -2.277 12.644 1.00110.40 C +ATOM 33169 C GLY R 103 12.847 -2.135 12.682 1.00 88.04 C +ATOM 33170 O GLY R 103 12.122 -2.816 11.980 1.00 69.54 O +ATOM 33171 N THR R 104 12.374 -1.235 13.520 1.00109.78 N +ATOM 33172 CA THR R 104 10.999 -0.845 13.485 1.00112.08 C +ATOM 33173 C THR R 104 10.886 0.467 12.750 1.00103.86 C +ATOM 33174 O THR R 104 9.833 0.749 12.196 1.00137.90 O +ATOM 33175 CB THR R 104 10.379 -0.747 14.909 1.00137.26 C +ATOM 33176 OG1 THR R 104 11.003 0.289 15.686 1.00155.81 O +ATOM 33177 CG2 THR R 104 10.522 -2.085 15.650 1.00147.83 C +ATOM 33178 N VAL R 105 11.928 1.297 12.793 1.00 85.88 N +ATOM 33179 CA VAL R 105 11.799 2.666 12.317 1.00 95.82 C +ATOM 33180 C VAL R 105 11.383 2.665 10.844 1.00109.92 C +ATOM 33181 O VAL R 105 11.848 1.845 10.046 1.00 97.70 O +ATOM 33182 CB VAL R 105 13.071 3.528 12.559 1.00110.87 C +ATOM 33183 CG1 VAL R 105 13.302 4.544 11.427 1.00140.13 C +ATOM 33184 CG2 VAL R 105 12.989 4.277 13.892 1.00105.86 C +ATOM 33185 N ALA R 106 10.493 3.608 10.512 1.00119.28 N +ATOM 33186 CA ALA R 106 9.852 3.700 9.204 1.00102.50 C +ATOM 33187 C ALA R 106 10.887 3.911 8.103 1.00112.63 C +ATOM 33188 O ALA R 106 11.768 4.771 8.219 1.00163.19 O +ATOM 33189 CB ALA R 106 8.822 4.834 9.201 1.00 82.69 C +ATOM 33190 N ILE R 107 10.764 3.131 7.034 1.00109.84 N +ATOM 33191 CA ILE R 107 11.742 3.126 5.947 1.00112.79 C +ATOM 33192 C ILE R 107 11.947 4.521 5.296 1.00120.44 C +ATOM 33193 O ILE R 107 13.040 4.852 4.831 1.00 89.39 O +ATOM 33194 CB ILE R 107 11.345 2.080 4.881 1.00106.79 C +ATOM 33195 CG1 ILE R 107 12.499 1.825 3.914 1.00110.54 C +ATOM 33196 CG2 ILE R 107 10.093 2.527 4.121 1.00112.09 C +ATOM 33197 CD1 ILE R 107 13.787 1.366 4.575 1.00110.57 C +ATOM 33198 N ASN R 108 10.895 5.338 5.289 1.00134.57 N +ATOM 33199 CA ASN R 108 10.974 6.728 4.814 1.00130.17 C +ATOM 33200 C ASN R 108 11.784 7.599 5.769 1.00114.71 C +ATOM 33201 O ASN R 108 12.483 8.519 5.353 1.00136.24 O +ATOM 33202 CB ASN R 108 9.569 7.335 4.671 1.00126.56 C +ATOM 33203 CG ASN R 108 8.516 6.298 4.325 1.00153.42 C +ATOM 33204 OD1 ASN R 108 8.306 5.979 3.151 1.00217.66 O +ATOM 33205 ND2 ASN R 108 7.859 5.753 5.344 1.00131.60 N +ATOM 33206 N ASN R 109 11.654 7.310 7.053 1.00 99.35 N +ATOM 33207 CA ASN R 109 12.251 8.115 8.102 1.00110.55 C +ATOM 33208 C ASN R 109 13.685 7.715 8.418 1.00106.37 C +ATOM 33209 O ASN R 109 14.433 8.483 9.044 1.00160.92 O +ATOM 33210 CB ASN R 109 11.403 8.017 9.369 1.00134.86 C +ATOM 33211 CG ASN R 109 10.810 9.351 9.765 1.00158.35 C +ATOM 33212 OD1 ASN R 109 11.139 9.898 10.814 1.00186.46 O +ATOM 33213 ND2 ASN R 109 9.937 9.891 8.915 1.00160.66 N +ATOM 33214 N ARG R 110 14.072 6.525 7.957 1.00 97.66 N +ATOM 33215 CA ARG R 110 15.374 5.908 8.289 1.00 87.46 C +ATOM 33216 C ARG R 110 16.556 6.801 7.886 1.00 90.95 C +ATOM 33217 O ARG R 110 16.553 7.368 6.785 1.00138.68 O +ATOM 33218 CB ARG R 110 15.497 4.565 7.559 1.00 82.32 C +ATOM 33219 CG ARG R 110 16.470 3.586 8.179 1.00 91.22 C +ATOM 33220 CD ARG R 110 16.009 2.148 8.005 1.00105.83 C +ATOM 33221 NE ARG R 110 16.481 1.557 6.750 1.00110.97 N +ATOM 33222 CZ ARG R 110 17.269 0.484 6.662 1.00139.65 C +ATOM 33223 NH1 ARG R 110 17.691 -0.166 7.759 1.00144.44 N +ATOM 33224 NH2 ARG R 110 17.627 0.030 5.463 1.00140.56 N +ATOM 33225 N ILE R 111 17.535 6.968 8.775 1.00 67.71 N +ATOM 33226 CA ILE R 111 18.737 7.711 8.430 1.00 71.64 C +ATOM 33227 C ILE R 111 19.897 6.765 8.302 1.00 92.25 C +ATOM 33228 O ILE R 111 20.290 6.156 9.288 1.00100.48 O +ATOM 33229 CB ILE R 111 19.093 8.757 9.478 1.00 83.42 C +ATOM 33230 CG1 ILE R 111 17.996 9.830 9.528 1.00 91.76 C +ATOM 33231 CG2 ILE R 111 20.435 9.409 9.139 1.00109.05 C +ATOM 33232 CD1 ILE R 111 18.080 10.791 10.715 1.00 68.85 C +ATOM 33233 N PRO R 112 20.463 6.634 7.079 1.00106.27 N +ATOM 33234 CA PRO R 112 21.583 5.713 6.873 1.00 89.96 C +ATOM 33235 C PRO R 112 22.913 6.299 7.375 1.00 96.63 C +ATOM 33236 O PRO R 112 23.254 7.453 7.067 1.00 91.11 O +ATOM 33237 CB PRO R 112 21.609 5.550 5.366 1.00 84.41 C +ATOM 33238 CG PRO R 112 21.149 6.876 4.847 1.00 95.03 C +ATOM 33239 CD PRO R 112 20.231 7.472 5.886 1.00100.89 C +ATOM 33240 N LEU R 113 23.608 5.531 8.208 1.00 88.41 N +ATOM 33241 CA LEU R 113 24.794 6.016 8.902 1.00 79.93 C +ATOM 33242 C LEU R 113 26.035 5.363 8.353 1.00 76.58 C +ATOM 33243 O LEU R 113 26.055 4.160 8.047 1.00 85.14 O +ATOM 33244 CB LEU R 113 24.713 5.740 10.414 1.00 70.65 C +ATOM 33245 CG LEU R 113 24.001 6.810 11.235 1.00 67.66 C +ATOM 33246 CD1 LEU R 113 24.131 6.399 12.681 1.00 87.98 C +ATOM 33247 CD2 LEU R 113 24.586 8.202 11.038 1.00 66.62 C +ATOM 33248 N GLN R 114 27.116 6.113 8.390 1.00 72.06 N +ATOM 33249 CA GLN R 114 28.408 5.511 8.149 1.00 86.34 C +ATOM 33250 C GLN R 114 29.344 6.269 9.042 1.00 84.08 C +ATOM 33251 O GLN R 114 29.180 7.478 9.209 1.00139.44 O +ATOM 33252 CB GLN R 114 28.808 5.649 6.678 1.00103.46 C +ATOM 33253 CG GLN R 114 29.800 4.610 6.165 1.00 91.40 C +ATOM 33254 CD GLN R 114 30.839 5.264 5.292 1.00 96.26 C +ATOM 33255 OE1 GLN R 114 32.019 5.037 5.495 1.00 58.47 O +ATOM 33256 NE2 GLN R 114 30.414 6.223 4.446 1.00125.49 N +ATOM 33257 N SER R 115 30.373 5.596 9.530 1.00 82.05 N +ATOM 33258 CA SER R 115 31.399 6.248 10.331 1.00 77.52 C +ATOM 33259 C SER R 115 31.952 7.490 9.521 1.00 55.95 C +ATOM 33260 O SER R 115 32.011 7.526 8.397 1.00 29.53 O +ATOM 33261 CB SER R 115 32.476 5.215 10.763 1.00 66.00 C +ATOM 33262 OG SER R 115 33.071 4.628 9.626 1.00110.41 O +ATOM 33263 N LEU R 116 32.523 8.408 10.204 1.00 59.82 N +ATOM 33264 CA LEU R 116 32.646 9.804 9.889 1.00 65.06 C +ATOM 33265 C LEU R 116 33.688 9.969 8.828 1.00 60.70 C +ATOM 33266 O LEU R 116 34.835 9.543 9.014 1.00 80.62 O +ATOM 33267 CB LEU R 116 33.049 10.534 11.208 1.00 92.26 C +ATOM 33268 CG LEU R 116 31.994 10.474 12.340 1.00 93.78 C +ATOM 33269 CD1 LEU R 116 32.229 9.278 13.286 1.00 86.09 C +ATOM 33270 CD2 LEU R 116 32.023 11.787 13.114 1.00 84.90 C +ATOM 33271 N THR R 117 33.366 10.772 7.825 1.00 70.16 N +ATOM 33272 CA THR R 117 34.348 11.191 6.810 1.00102.55 C +ATOM 33273 C THR R 117 35.570 11.862 7.434 1.00 99.21 C +ATOM 33274 O THR R 117 35.442 12.681 8.329 1.00 98.82 O +ATOM 33275 CB THR R 117 33.772 12.218 5.804 1.00133.28 C +ATOM 33276 OG1 THR R 117 32.539 11.724 5.270 1.00147.23 O +ATOM 33277 CG2 THR R 117 34.737 12.445 4.666 1.00153.73 C +ATOM 33278 N ALA R 118 36.753 11.429 7.013 1.00114.49 N +ATOM 33279 CA ALA R 118 37.989 11.751 7.734 1.00100.83 C +ATOM 33280 C ALA R 118 38.844 12.594 6.843 1.00 74.43 C +ATOM 33281 O ALA R 118 39.077 12.244 5.688 1.00 67.95 O +ATOM 33282 CB ALA R 118 38.735 10.471 8.187 1.00 91.88 C +ATOM 33283 N ALA R 119 39.481 13.556 7.467 1.00 78.08 N +ATOM 33284 CA ALA R 119 40.379 14.464 6.788 1.00104.92 C +ATOM 33285 C ALA R 119 41.812 13.929 6.598 1.00 96.78 C +ATOM 33286 O ALA R 119 42.294 13.121 7.389 1.00 93.55 O +ATOM 33287 CB ALA R 119 40.412 15.753 7.574 1.00123.23 C +ATOM 33288 N ASN R 120 42.512 14.434 5.588 1.00 92.54 N +ATOM 33289 CA ASN R 120 43.914 14.105 5.428 1.00 89.71 C +ATOM 33290 C ASN R 120 44.824 15.185 5.990 1.00 82.48 C +ATOM 33291 O ASN R 120 45.862 14.890 6.619 1.00120.04 O +ATOM 33292 CB ASN R 120 44.283 13.856 3.966 1.00102.38 C +ATOM 33293 CG ASN R 120 45.749 13.412 3.806 1.00122.01 C +ATOM 33294 OD1 ASN R 120 46.420 13.865 2.879 1.00173.93 O +ATOM 33295 ND2 ASN R 120 46.272 12.587 4.747 1.00 92.95 N +ATOM 33296 N ILE R 121 44.537 16.431 5.645 1.00 60.10 N +ATOM 33297 CA ILE R 121 45.299 17.509 6.204 1.00 66.90 C +ATOM 33298 C ILE R 121 44.375 18.241 7.151 1.00 87.82 C +ATOM 33299 O ILE R 121 43.192 18.383 6.879 1.00 63.92 O +ATOM 33300 CB ILE R 121 45.883 18.468 5.131 1.00 62.30 C +ATOM 33301 CG1 ILE R 121 44.804 19.354 4.488 1.00 48.05 C +ATOM 33302 CG2 ILE R 121 46.676 17.692 4.077 1.00 57.57 C +ATOM 33303 CD1 ILE R 121 44.898 20.821 4.877 1.00 50.30 C +ATOM 33304 N MET R 122 44.912 18.685 8.289 1.00 92.18 N +ATOM 33305 CA MET R 122 44.161 19.611 9.131 1.00 71.36 C +ATOM 33306 C MET R 122 44.955 20.875 9.371 1.00 63.93 C +ATOM 33307 O MET R 122 46.181 20.865 9.292 1.00 51.75 O +ATOM 33308 CB MET R 122 43.792 18.958 10.433 1.00 70.06 C +ATOM 33309 CG MET R 122 44.959 18.444 11.251 1.00 75.45 C +ATOM 33310 SD MET R 122 44.539 18.493 12.998 1.00112.27 S +ATOM 33311 CE MET R 122 46.048 19.093 13.743 1.00 68.16 C +ATOM 33312 N VAL R 123 44.251 21.998 9.366 1.00 70.91 N +ATOM 33313 CA VAL R 123 44.909 23.305 9.399 1.00 78.51 C +ATOM 33314 C VAL R 123 44.468 24.016 10.644 1.00 88.94 C +ATOM 33315 O VAL R 123 43.282 24.159 10.898 1.00 69.36 O +ATOM 33316 CB VAL R 123 44.598 24.212 8.190 1.00 81.15 C +ATOM 33317 CG1 VAL R 123 43.146 24.108 7.773 1.00 90.83 C +ATOM 33318 CG2 VAL R 123 44.945 25.664 8.509 1.00110.93 C +ATOM 33319 N GLU R 124 45.439 24.412 11.454 1.00110.90 N +ATOM 33320 CA GLU R 124 45.152 25.203 12.648 1.00118.08 C +ATOM 33321 C GLU R 124 46.027 26.419 12.680 1.00113.95 C +ATOM 33322 O GLU R 124 46.926 26.579 11.859 1.00118.23 O +ATOM 33323 CB GLU R 124 45.366 24.405 13.927 1.00116.57 C +ATOM 33324 CG GLU R 124 46.419 23.313 13.839 1.00122.97 C +ATOM 33325 CD GLU R 124 46.271 22.283 14.944 1.00125.76 C +ATOM 33326 OE1 GLU R 124 45.131 21.998 15.358 1.00 76.18 O +ATOM 33327 OE2 GLU R 124 47.316 21.859 15.480 1.00198.03 O +ATOM 33328 N GLY R 125 45.723 27.313 13.602 1.00106.63 N +ATOM 33329 CA GLY R 125 46.386 28.599 13.631 1.00111.04 C +ATOM 33330 C GLY R 125 46.035 29.386 14.862 1.00107.60 C +ATOM 33331 O GLY R 125 45.445 28.860 15.808 1.00114.08 O +ATOM 33332 N SER R 126 46.323 30.686 14.827 1.00102.27 N +ATOM 33333 CA SER R 126 46.066 31.543 15.983 1.00 93.15 C +ATOM 33334 C SER R 126 46.003 32.993 15.597 1.00 65.93 C +ATOM 33335 O SER R 126 46.588 33.388 14.606 1.00 58.13 O +ATOM 33336 CB SER R 126 47.201 31.441 16.967 1.00118.43 C +ATOM 33337 OG SER R 126 48.043 30.364 16.747 1.00142.97 O +ATOM 33338 N ILE R 127 45.200 33.767 16.308 1.00 52.53 N +ATOM 33339 CA ILE R 127 45.266 35.178 16.140 1.00 63.00 C +ATOM 33340 C ILE R 127 46.471 35.560 16.961 1.00 72.71 C +ATOM 33341 O ILE R 127 46.410 35.707 18.167 1.00 64.66 O +ATOM 33342 CB ILE R 127 43.997 35.925 16.603 1.00 89.21 C +ATOM 33343 CG1 ILE R 127 42.811 35.611 15.679 1.00 96.06 C +ATOM 33344 CG2 ILE R 127 44.224 37.446 16.625 1.00108.73 C +ATOM 33345 CD1 ILE R 127 41.460 35.643 16.382 1.00103.94 C +ATOM 33346 N ILE R 128 47.551 35.838 16.257 1.00101.73 N +ATOM 33347 CA ILE R 128 48.792 36.320 16.851 1.00100.70 C +ATOM 33348 C ILE R 128 48.720 37.867 16.823 1.00 75.99 C +ATOM 33349 O ILE R 128 48.899 38.504 15.783 1.00127.52 O +ATOM 33350 CB ILE R 128 50.005 35.727 16.074 1.00113.54 C +ATOM 33351 CG1 ILE R 128 49.914 36.054 14.571 1.00145.45 C +ATOM 33352 CG2 ILE R 128 49.982 34.202 16.151 1.00 94.01 C +ATOM 33353 CD1 ILE R 128 51.256 36.047 13.869 1.00137.60 C +ATOM 33354 N GLY R 129 48.310 38.452 17.926 1.00 47.64 N +ATOM 33355 CA GLY R 129 48.558 39.840 18.147 1.00 47.52 C +ATOM 33356 C GLY R 129 47.452 40.752 17.674 1.00 65.40 C +ATOM 33357 O GLY R 129 46.939 40.663 16.549 1.00 62.69 O +ATOM 33358 N TYR R 130 47.171 41.739 18.519 1.00115.07 N +ATOM 33359 CA TYR R 130 46.428 42.949 18.135 1.00113.52 C +ATOM 33360 C TYR R 130 47.075 44.093 18.879 1.00129.59 C +ATOM 33361 O TYR R 130 47.000 44.159 20.102 1.00171.89 O +ATOM 33362 CB TYR R 130 44.949 42.820 18.529 1.00103.12 C +ATOM 33363 CG TYR R 130 44.093 44.041 18.317 1.00105.46 C +ATOM 33364 CD1 TYR R 130 44.269 45.180 19.089 1.00113.98 C +ATOM 33365 CD2 TYR R 130 43.060 44.030 17.376 1.00122.30 C +ATOM 33366 CE1 TYR R 130 43.458 46.287 18.909 1.00148.74 C +ATOM 33367 CE2 TYR R 130 42.261 45.135 17.171 1.00124.18 C +ATOM 33368 CZ TYR R 130 42.464 46.261 17.932 1.00155.97 C +ATOM 33369 OH TYR R 130 41.654 47.357 17.724 1.00204.64 O +ATOM 33370 N GLU R 131 47.837 44.911 18.171 1.00118.89 N +ATOM 33371 CA GLU R 131 48.366 46.133 18.770 1.00138.25 C +ATOM 33372 C GLU R 131 47.429 47.288 18.423 1.00119.96 C +ATOM 33373 O GLU R 131 46.812 47.280 17.361 1.00113.30 O +ATOM 33374 CB GLU R 131 49.787 46.380 18.267 1.00140.40 C +ATOM 33375 CG GLU R 131 50.552 47.494 18.973 1.00121.21 C +ATOM 33376 CD GLU R 131 51.321 47.035 20.206 1.00118.32 C +ATOM 33377 OE1 GLU R 131 51.740 45.848 20.262 1.00 87.02 O +ATOM 33378 OE2 GLU R 131 51.491 47.873 21.124 1.00138.42 O +ATOM 33379 N SER R 132 47.310 48.258 19.323 1.00 97.26 N +ATOM 33380 CA SER R 132 46.299 49.299 19.171 1.00 99.90 C +ATOM 33381 C SER R 132 46.922 50.695 19.086 1.00125.65 C +ATOM 33382 O SER R 132 47.882 51.004 19.796 1.00163.09 O +ATOM 33383 CB SER R 132 45.292 49.244 20.324 1.00100.62 C +ATOM 33384 OG SER R 132 45.390 50.395 21.157 1.00 93.41 O +ATOM 33385 N ASN R 133 46.332 51.553 18.254 1.00131.76 N +ATOM 33386 CA ASN R 133 46.944 52.845 17.890 1.00119.21 C +ATOM 33387 C ASN R 133 48.416 52.691 17.540 1.00120.44 C +ATOM 33388 O ASN R 133 49.285 53.326 18.141 1.00100.68 O +ATOM 33389 CB ASN R 133 46.784 53.869 19.004 1.00 96.71 C +ATOM 33390 CG ASN R 133 45.337 54.130 19.331 1.00114.90 C +ATOM 33391 OD1 ASN R 133 44.443 54.027 18.469 1.00137.57 O +ATOM 33392 ND2 ASN R 133 45.084 54.458 20.581 1.00136.25 N +ATOM 33393 N VAL R 134 48.677 51.832 16.559 1.00121.67 N +ATOM 33394 CA VAL R 134 50.026 51.583 16.086 1.00125.43 C +ATOM 33395 C VAL R 134 50.510 52.858 15.399 1.00131.08 C +ATOM 33396 O VAL R 134 51.682 53.227 15.502 1.00103.95 O +ATOM 33397 CB VAL R 134 50.060 50.377 15.116 1.00127.26 C +ATOM 33398 CG1 VAL R 134 51.487 50.065 14.684 1.00138.01 C +ATOM 33399 CG2 VAL R 134 49.438 49.147 15.770 1.00134.18 C +ATOM 33400 N LYS R 135 49.582 53.548 14.739 1.00140.80 N +ATOM 33401 CA LYS R 135 49.803 54.934 14.340 1.00136.69 C +ATOM 33402 C LYS R 135 48.580 55.796 14.615 1.00152.51 C +ATOM 33403 O LYS R 135 47.447 55.299 14.736 1.00140.20 O +ATOM 33404 CB LYS R 135 50.138 55.011 12.858 1.00165.34 C +ATOM 33405 CG LYS R 135 51.422 54.290 12.490 1.00185.82 C +ATOM 33406 CD LYS R 135 51.628 54.317 10.988 1.00234.32 C +ATOM 33407 CE LYS R 135 52.898 53.596 10.589 1.00237.71 C +ATOM 33408 NZ LYS R 135 53.344 54.042 9.244 1.00272.88 N +ATOM 33409 N SER R 136 48.814 57.103 14.692 1.00177.29 N +ATOM 33410 CA SER R 136 47.736 58.061 14.929 1.00192.37 C +ATOM 33411 C SER R 136 48.155 59.483 14.569 1.00192.27 C +ATOM 33412 O SER R 136 49.342 59.799 14.552 1.00175.32 O +ATOM 33413 CB SER R 136 47.268 57.997 16.387 1.00177.73 C +ATOM 33414 OG SER R 136 47.324 59.270 17.011 1.00141.66 O +ATOM 33415 N GLY R 137 47.170 60.330 14.278 1.00179.25 N +ATOM 33416 CA GLY R 137 47.441 61.728 13.963 1.00182.76 C +ATOM 33417 C GLY R 137 46.204 62.604 13.939 1.00191.34 C +ATOM 33418 O GLY R 137 45.083 62.130 14.132 1.00195.74 O +ATOM 33419 N GLY R 138 46.413 63.902 13.747 1.00192.91 N +ATOM 33420 CA GLY R 138 45.309 64.851 13.704 1.00196.56 C +ATOM 33421 C GLY R 138 45.711 66.193 13.131 1.00190.82 C +ATOM 33422 O GLY R 138 46.839 66.651 13.329 1.00134.39 O +ATOM 33423 N VAL R 139 44.776 66.820 12.420 1.00181.20 N +ATOM 33424 CA VAL R 139 44.983 68.155 11.877 1.00145.53 C +ATOM 33425 C VAL R 139 43.707 68.979 12.061 1.00118.17 C +ATOM 33426 O VAL R 139 42.634 68.594 11.592 1.00 80.20 O +ATOM 33427 CB VAL R 139 45.361 68.110 10.377 1.00122.23 C +ATOM 33428 CG1 VAL R 139 45.445 69.520 9.824 1.00135.53 C +ATOM 33429 CG2 VAL R 139 46.679 67.375 10.161 1.00 97.52 C +ATOM 33430 N GLY R 140 43.848 70.141 12.693 1.00119.38 N +ATOM 33431 CA GLY R 140 42.723 71.047 12.890 1.00130.73 C +ATOM 33432 C GLY R 140 43.087 72.521 12.912 1.00165.06 C +ATOM 33433 O GLY R 140 44.169 72.906 13.368 1.00184.22 O +ATOM 33434 N ALA R 141 42.169 73.358 12.431 1.00174.48 N +ATOM 33435 CA ALA R 141 42.366 74.808 12.466 1.00152.89 C +ATOM 33436 C ALA R 141 41.058 75.556 12.730 1.00137.69 C +ATOM 33437 O ALA R 141 39.989 75.175 12.245 1.00123.17 O +ATOM 33438 CB ALA R 141 43.008 75.289 11.176 1.00135.66 C +ATOM 33439 N ARG R 142 41.146 76.594 13.551 1.00139.38 N +ATOM 33440 CA ARG R 142 40.024 77.487 13.753 1.00142.53 C +ATOM 33441 C ARG R 142 40.486 78.915 13.529 1.00173.95 C +ATOM 33442 O ARG R 142 41.638 79.255 13.813 1.00192.95 O +ATOM 33443 CB ARG R 142 39.425 77.331 15.148 1.00138.12 C +ATOM 33444 CG ARG R 142 38.186 78.194 15.360 1.00152.56 C +ATOM 33445 CD ARG R 142 37.077 77.466 16.106 1.00179.10 C +ATOM 33446 NE ARG R 142 37.193 77.569 17.555 1.00175.64 N +ATOM 33447 CZ ARG R 142 36.662 76.713 18.424 1.00181.37 C +ATOM 33448 NH1 ARG R 142 36.030 75.623 18.002 1.00180.56 N +ATOM 33449 NH2 ARG R 142 36.806 76.924 19.729 1.00183.63 N +ATOM 33450 N TYR R 143 39.602 79.722 12.946 1.00188.51 N +ATOM 33451 CA TYR R 143 39.954 81.064 12.488 1.00177.42 C +ATOM 33452 C TYR R 143 38.911 82.080 12.979 1.00126.79 C +ATOM 33453 O TYR R 143 38.022 82.467 12.226 1.00 98.70 O +ATOM 33454 CB TYR R 143 40.064 81.070 10.954 1.00169.04 C +ATOM 33455 CG TYR R 143 40.579 82.350 10.373 1.00182.91 C +ATOM 33456 CD1 TYR R 143 41.923 82.690 10.478 1.00193.07 C +ATOM 33457 CD2 TYR R 143 39.737 83.200 9.667 1.00191.15 C +ATOM 33458 CE1 TYR R 143 42.408 83.858 9.914 1.00202.41 C +ATOM 33459 CE2 TYR R 143 40.214 84.368 9.089 1.00190.27 C +ATOM 33460 CZ TYR R 143 41.549 84.694 9.220 1.00196.15 C +ATOM 33461 OH TYR R 143 42.027 85.851 8.656 1.00191.69 O +ATOM 33462 N GLY R 145 33.893 82.926 13.834 1.00135.79 N +ATOM 33463 CA GLY R 145 35.020 82.030 14.047 1.00163.20 C +ATOM 33464 C GLY R 145 34.734 80.589 13.633 1.00189.26 C +ATOM 33465 O GLY R 145 33.860 79.890 14.184 1.00157.19 O +ATOM 33466 N ILE R 146 35.459 80.165 12.610 1.00224.95 N +ATOM 33467 CA ILE R 146 35.107 78.968 11.838 1.00208.38 C +ATOM 33468 C ILE R 146 36.221 77.940 11.988 1.00191.22 C +ATOM 33469 O ILE R 146 37.398 78.300 11.947 1.00224.32 O +ATOM 33470 CB ILE R 146 34.895 79.300 10.334 1.00194.82 C +ATOM 33471 CG1 ILE R 146 34.158 80.642 10.166 1.00194.76 C +ATOM 33472 CG2 ILE R 146 34.124 78.183 9.642 1.00167.21 C +ATOM 33473 CD1 ILE R 146 35.067 81.829 9.912 1.00169.04 C +ATOM 33474 N GLY R 147 35.870 76.665 12.162 1.00135.13 N +ATOM 33475 CA GLY R 147 36.900 75.647 12.391 1.00145.74 C +ATOM 33476 C GLY R 147 36.578 74.246 11.904 1.00135.09 C +ATOM 33477 O GLY R 147 35.421 73.870 11.785 1.00 93.17 O +ATOM 33478 N ALA R 148 37.626 73.471 11.633 1.00160.85 N +ATOM 33479 CA ALA R 148 37.475 72.051 11.330 1.00146.67 C +ATOM 33480 C ALA R 148 38.688 71.269 11.809 1.00165.40 C +ATOM 33481 O ALA R 148 39.720 71.846 12.196 1.00132.30 O +ATOM 33482 CB ALA R 148 37.271 71.836 9.843 1.00113.93 C +ATOM 33483 N ASP R 149 38.535 69.951 11.844 1.00180.95 N +ATOM 33484 CA ASP R 149 39.624 69.079 12.258 1.00190.00 C +ATOM 33485 C ASP R 149 39.325 67.635 11.884 1.00164.09 C +ATOM 33486 O ASP R 149 38.169 67.215 11.892 1.00 89.92 O +ATOM 33487 CB ASP R 149 39.901 69.205 13.772 1.00197.72 C +ATOM 33488 CG ASP R 149 38.949 68.396 14.610 1.00168.53 C +ATOM 33489 OD1 ASP R 149 37.799 68.840 14.769 1.00168.42 O +ATOM 33490 OD2 ASP R 149 39.367 67.353 15.140 1.00122.20 O +ATOM 33491 N THR R 150 40.375 66.885 11.565 1.00174.40 N +ATOM 33492 CA THR R 150 40.269 65.436 11.515 1.00171.84 C +ATOM 33493 C THR R 150 41.284 64.797 12.456 1.00198.35 C +ATOM 33494 O THR R 150 42.309 65.391 12.801 1.00163.00 O +ATOM 33495 CB THR R 150 40.483 64.873 10.098 1.00147.60 C +ATOM 33496 OG1 THR R 150 41.786 65.244 9.633 1.00157.86 O +ATOM 33497 CG2 THR R 150 39.424 65.387 9.151 1.00125.59 C +ATOM 33498 N GLN R 151 40.955 63.593 12.901 1.00216.33 N +ATOM 33499 CA GLN R 151 41.852 62.786 13.703 1.00195.76 C +ATOM 33500 C GLN R 151 41.772 61.350 13.221 1.00168.77 C +ATOM 33501 O GLN R 151 40.712 60.904 12.819 1.00110.98 O +ATOM 33502 CB GLN R 151 41.433 62.873 15.164 1.00172.34 C +ATOM 33503 CG GLN R 151 41.750 64.213 15.789 1.00163.35 C +ATOM 33504 CD GLN R 151 40.910 64.486 17.011 1.00166.28 C +ATOM 33505 OE1 GLN R 151 40.673 63.583 17.809 1.00185.20 O +ATOM 33506 NE2 GLN R 151 40.446 65.724 17.161 1.00162.25 N +ATOM 33507 N TYR R 152 42.896 60.639 13.218 1.00147.38 N +ATOM 33508 CA TYR R 152 42.881 59.253 12.792 1.00112.99 C +ATOM 33509 C TYR R 152 43.738 58.370 13.669 1.00136.56 C +ATOM 33510 O TYR R 152 44.751 58.811 14.219 1.00154.01 O +ATOM 33511 CB TYR R 152 43.334 59.142 11.353 1.00103.89 C +ATOM 33512 CG TYR R 152 44.744 58.600 11.149 1.00 97.47 C +ATOM 33513 CD1 TYR R 152 45.867 59.319 11.520 1.00 78.23 C +ATOM 33514 CD2 TYR R 152 44.941 57.417 10.444 1.00 98.13 C +ATOM 33515 CE1 TYR R 152 47.134 58.834 11.261 1.00 80.63 C +ATOM 33516 CE2 TYR R 152 46.218 56.966 10.105 1.00 71.64 C +ATOM 33517 CZ TYR R 152 47.305 57.668 10.516 1.00 70.28 C +ATOM 33518 OH TYR R 152 48.573 57.226 10.167 1.00 83.12 O +ATOM 33519 N GLN R 153 43.311 57.123 13.822 1.00165.56 N +ATOM 33520 CA GLN R 153 44.131 56.116 14.479 1.00171.88 C +ATOM 33521 C GLN R 153 44.083 54.815 13.691 1.00142.22 C +ATOM 33522 O GLN R 153 43.113 54.554 12.976 1.00125.32 O +ATOM 33523 CB GLN R 153 43.641 55.895 15.914 1.00187.80 C +ATOM 33524 CG GLN R 153 43.801 57.102 16.852 1.00204.60 C +ATOM 33525 CD GLN R 153 43.180 56.836 18.237 1.00218.55 C +ATOM 33526 OE1 GLN R 153 42.329 55.952 18.393 1.00246.58 O +ATOM 33527 NE2 GLN R 153 43.616 57.588 19.242 1.00215.11 N +ATOM 33528 N LEU R 154 45.134 54.010 13.810 1.00112.41 N +ATOM 33529 CA LEU R 154 45.098 52.687 13.223 1.00115.22 C +ATOM 33530 C LEU R 154 45.804 51.624 14.063 1.00147.61 C +ATOM 33531 O LEU R 154 46.847 51.875 14.690 1.00143.08 O +ATOM 33532 CB LEU R 154 45.672 52.707 11.813 1.00105.60 C +ATOM 33533 CG LEU R 154 47.191 52.886 11.714 1.00119.76 C +ATOM 33534 CD1 LEU R 154 47.919 51.554 11.594 1.00 97.29 C +ATOM 33535 CD2 LEU R 154 47.509 53.785 10.528 1.00166.00 C +ATOM 33536 N ASP R 155 45.254 50.408 13.972 1.00176.85 N +ATOM 33537 CA ASP R 155 45.610 49.261 14.819 1.00125.45 C +ATOM 33538 C ASP R 155 46.118 48.124 13.924 1.00 87.20 C +ATOM 33539 O ASP R 155 45.810 48.098 12.732 1.00 93.57 O +ATOM 33540 CB ASP R 155 44.371 48.809 15.615 1.00124.52 C +ATOM 33541 CG ASP R 155 43.624 49.977 16.267 1.00145.34 C +ATOM 33542 OD1 ASP R 155 42.862 50.679 15.566 1.00119.28 O +ATOM 33543 OD2 ASP R 155 43.836 50.210 17.476 1.00184.17 O +ATOM 33544 N GLN R 156 46.850 47.179 14.492 1.00 66.84 N +ATOM 33545 CA GLN R 156 47.309 46.008 13.736 1.00 71.66 C +ATOM 33546 C GLN R 156 46.675 44.676 14.228 1.00 88.65 C +ATOM 33547 O GLN R 156 46.193 44.565 15.356 1.00117.21 O +ATOM 33548 CB GLN R 156 48.812 45.906 13.817 1.00 61.45 C +ATOM 33549 CG GLN R 156 49.426 44.915 12.858 1.00 65.42 C +ATOM 33550 CD GLN R 156 50.899 45.188 12.624 1.00 93.07 C +ATOM 33551 OE1 GLN R 156 51.505 46.056 13.277 1.00125.00 O +ATOM 33552 NE2 GLN R 156 51.496 44.460 11.684 1.00112.10 N +ATOM 33553 N ILE R 157 46.643 43.682 13.350 1.00 68.07 N +ATOM 33554 CA ILE R 157 46.135 42.377 13.677 1.00 61.36 C +ATOM 33555 C ILE R 157 46.886 41.361 12.803 1.00 54.72 C +ATOM 33556 O ILE R 157 47.097 41.586 11.626 1.00 56.71 O +ATOM 33557 CB ILE R 157 44.587 42.302 13.475 1.00 68.29 C +ATOM 33558 CG1 ILE R 157 43.965 41.175 14.338 1.00 92.83 C +ATOM 33559 CG2 ILE R 157 44.239 42.053 12.021 1.00 64.53 C +ATOM 33560 CD1 ILE R 157 42.437 41.140 14.365 1.00 64.71 C +ATOM 33561 N ALA R 158 47.261 40.229 13.372 1.00 67.58 N +ATOM 33562 CA ALA R 158 47.995 39.234 12.611 1.00 94.01 C +ATOM 33563 C ALA R 158 47.450 37.851 12.869 1.00 83.97 C +ATOM 33564 O ALA R 158 46.880 37.576 13.933 1.00129.38 O +ATOM 33565 CB ALA R 158 49.487 39.289 12.940 1.00124.92 C +ATOM 33566 N VAL R 159 47.653 36.971 11.899 1.00 58.30 N +ATOM 33567 CA VAL R 159 47.055 35.660 11.954 1.00 66.41 C +ATOM 33568 C VAL R 159 48.045 34.646 11.418 1.00 60.78 C +ATOM 33569 O VAL R 159 48.571 34.777 10.325 1.00 46.08 O +ATOM 33570 CB VAL R 159 45.705 35.600 11.165 1.00 87.05 C +ATOM 33571 CG1 VAL R 159 45.342 34.169 10.786 1.00 89.54 C +ATOM 33572 CG2 VAL R 159 44.554 36.232 11.959 1.00 82.73 C +ATOM 33573 N ASN R 160 48.225 33.591 12.190 1.00 76.51 N +ATOM 33574 CA ASN R 160 48.916 32.412 11.733 1.00 67.75 C +ATOM 33575 C ASN R 160 47.859 31.421 11.248 1.00 48.85 C +ATOM 33576 O ASN R 160 46.940 31.069 11.984 1.00 40.60 O +ATOM 33577 CB ASN R 160 49.770 31.847 12.895 1.00 67.09 C +ATOM 33578 CG ASN R 160 50.527 30.572 12.512 1.00 75.77 C +ATOM 33579 OD1 ASN R 160 49.949 29.599 12.037 1.00 81.17 O +ATOM 33580 ND2 ASN R 160 51.799 30.515 12.871 1.00113.43 N +ATOM 33581 N LEU R 161 48.052 30.898 10.059 1.00 48.91 N +ATOM 33582 CA LEU R 161 47.471 29.592 9.691 1.00 59.12 C +ATOM 33583 C LEU R 161 48.545 28.554 9.284 1.00 59.98 C +ATOM 33584 O LEU R 161 49.608 28.912 8.780 1.00 75.14 O +ATOM 33585 CB LEU R 161 46.535 29.791 8.530 1.00 60.60 C +ATOM 33586 CG LEU R 161 45.347 30.691 8.834 1.00 78.39 C +ATOM 33587 CD1 LEU R 161 44.611 30.982 7.542 1.00110.85 C +ATOM 33588 CD2 LEU R 161 44.444 30.015 9.833 1.00 84.61 C +ATOM 33589 N ARG R 162 48.288 27.279 9.522 1.00 49.85 N +ATOM 33590 CA ARG R 162 49.266 26.275 9.176 1.00 70.07 C +ATOM 33591 C ARG R 162 48.671 24.902 8.883 1.00 75.72 C +ATOM 33592 O ARG R 162 47.873 24.376 9.663 1.00 76.13 O +ATOM 33593 CB ARG R 162 50.377 26.186 10.244 1.00102.50 C +ATOM 33594 CG ARG R 162 49.979 25.741 11.653 1.00124.03 C +ATOM 33595 CD ARG R 162 51.223 25.311 12.455 1.00 95.81 C +ATOM 33596 NE ARG R 162 50.924 24.694 13.747 1.00 90.20 N +ATOM 33597 CZ ARG R 162 50.587 25.377 14.850 1.00119.51 C +ATOM 33598 NH1 ARG R 162 50.483 26.714 14.835 1.00139.00 N +ATOM 33599 NH2 ARG R 162 50.311 24.723 15.973 1.00101.32 N +ATOM 33600 N VAL R 163 49.134 24.311 7.775 1.00 78.70 N +ATOM 33601 CA VAL R 163 48.714 22.977 7.321 1.00 85.20 C +ATOM 33602 C VAL R 163 49.559 21.898 7.932 1.00 87.29 C +ATOM 33603 O VAL R 163 50.777 21.913 7.799 1.00 89.84 O +ATOM 33604 CB VAL R 163 48.890 22.780 5.817 1.00 79.34 C +ATOM 33605 CG1 VAL R 163 48.470 21.364 5.428 1.00 60.34 C +ATOM 33606 CG2 VAL R 163 48.107 23.863 5.064 1.00103.19 C +ATOM 33607 N VAL R 164 48.892 20.983 8.632 1.00 85.03 N +ATOM 33608 CA VAL R 164 49.545 19.899 9.324 1.00 87.42 C +ATOM 33609 C VAL R 164 49.126 18.630 8.644 1.00 69.86 C +ATOM 33610 O VAL R 164 47.954 18.416 8.412 1.00 45.93 O +ATOM 33611 CB VAL R 164 49.141 19.822 10.808 1.00129.79 C +ATOM 33612 CG1 VAL R 164 49.811 18.627 11.480 1.00148.51 C +ATOM 33613 CG2 VAL R 164 49.530 21.103 11.535 1.00166.72 C +ATOM 33614 N ASN R 165 50.104 17.772 8.405 1.00 66.24 N +ATOM 33615 CA ASN R 165 49.844 16.481 7.825 1.00 66.00 C +ATOM 33616 C ASN R 165 49.457 15.466 8.882 1.00 86.40 C +ATOM 33617 O ASN R 165 50.255 15.150 9.789 1.00122.53 O +ATOM 33618 CB ASN R 165 51.066 15.955 7.102 1.00 77.22 C +ATOM 33619 CG ASN R 165 50.772 14.672 6.379 1.00101.58 C +ATOM 33620 OD1 ASN R 165 49.601 14.369 6.106 1.00127.68 O +ATOM 33621 ND2 ASN R 165 51.822 14.020 5.890 1.00134.60 N +ATOM 33622 N VAL R 166 48.247 14.932 8.754 1.00 90.86 N +ATOM 33623 CA VAL R 166 47.702 14.001 9.732 1.00 91.00 C +ATOM 33624 C VAL R 166 48.587 12.783 9.790 1.00 86.25 C +ATOM 33625 O VAL R 166 48.798 12.232 10.879 1.00139.68 O +ATOM 33626 CB VAL R 166 46.252 13.595 9.378 1.00106.84 C +ATOM 33627 CG1 VAL R 166 45.866 12.233 9.955 1.00 94.74 C +ATOM 33628 CG2 VAL R 166 45.286 14.691 9.817 1.00119.65 C +ATOM 33629 N SER R 167 49.111 12.379 8.639 1.00 67.14 N +ATOM 33630 CA SER R 167 49.774 11.105 8.542 1.00 81.88 C +ATOM 33631 C SER R 167 51.160 11.111 9.199 1.00 77.75 C +ATOM 33632 O SER R 167 51.739 10.039 9.446 1.00 68.07 O +ATOM 33633 CB SER R 167 49.872 10.700 7.079 1.00105.26 C +ATOM 33634 OG SER R 167 48.621 10.877 6.416 1.00111.00 O +ATOM 33635 N THR R 168 51.679 12.300 9.507 1.00 75.97 N +ATOM 33636 CA THR R 168 53.028 12.422 10.116 1.00 83.26 C +ATOM 33637 C THR R 168 53.175 13.447 11.253 1.00 77.55 C +ATOM 33638 O THR R 168 53.923 13.251 12.217 1.00 94.19 O +ATOM 33639 CB THR R 168 54.040 12.839 9.068 1.00 93.31 C +ATOM 33640 OG1 THR R 168 53.546 13.995 8.387 1.00 61.50 O +ATOM 33641 CG2 THR R 168 54.272 11.698 8.076 1.00125.16 C +ATOM 33642 N GLY R 169 52.392 14.505 11.192 1.00 67.38 N +ATOM 33643 CA GLY R 169 52.504 15.531 12.182 1.00 65.38 C +ATOM 33644 C GLY R 169 53.436 16.588 11.666 1.00 90.36 C +ATOM 33645 O GLY R 169 53.544 17.666 12.260 1.00130.58 O +ATOM 33646 N GLU R 170 54.125 16.307 10.553 1.00 94.55 N +ATOM 33647 CA GLU R 170 54.889 17.353 9.837 1.00100.02 C +ATOM 33648 C GLU R 170 53.941 18.509 9.519 1.00 80.29 C +ATOM 33649 O GLU R 170 52.868 18.301 8.999 1.00 89.16 O +ATOM 33650 CB GLU R 170 55.508 16.822 8.530 1.00 89.29 C +ATOM 33651 CG GLU R 170 56.752 15.974 8.731 1.00 84.37 C +ATOM 33652 CD GLU R 170 56.865 14.807 7.774 1.00 92.84 C +ATOM 33653 OE1 GLU R 170 55.878 14.525 7.037 1.00129.55 O +ATOM 33654 OE2 GLU R 170 57.932 14.142 7.774 1.00 78.82 O +ATOM 33655 N ILE R 171 54.298 19.705 9.931 1.00 61.54 N +ATOM 33656 CA ILE R 171 53.648 20.840 9.402 1.00 69.57 C +ATOM 33657 C ILE R 171 54.045 20.955 7.924 1.00 74.13 C +ATOM 33658 O ILE R 171 55.233 21.033 7.606 1.00 80.92 O +ATOM 33659 CB ILE R 171 54.035 22.086 10.202 1.00 87.13 C +ATOM 33660 CG1 ILE R 171 53.410 22.018 11.588 1.00 82.82 C +ATOM 33661 CG2 ILE R 171 53.590 23.344 9.460 1.00101.74 C +ATOM 33662 CD1 ILE R 171 54.037 22.980 12.561 1.00104.53 C +ATOM 33663 N LEU R 172 53.063 21.050 7.033 1.00102.13 N +ATOM 33664 CA LEU R 172 53.348 21.160 5.601 1.00126.65 C +ATOM 33665 C LEU R 172 53.397 22.613 5.092 1.00156.17 C +ATOM 33666 O LEU R 172 53.862 22.903 3.972 1.00148.41 O +ATOM 33667 CB LEU R 172 52.325 20.377 4.779 1.00126.66 C +ATOM 33668 CG LEU R 172 52.570 18.891 4.488 1.00140.95 C +ATOM 33669 CD1 LEU R 172 53.451 18.319 5.581 1.00103.16 C +ATOM 33670 CD2 LEU R 172 51.336 18.030 4.218 1.00173.06 C +ATOM 33671 N SER R 173 52.924 23.537 5.921 1.00179.17 N +ATOM 33672 CA SER R 173 52.978 24.961 5.576 1.00165.59 C +ATOM 33673 C SER R 173 52.603 25.844 6.753 1.00139.39 C +ATOM 33674 O SER R 173 51.597 25.594 7.426 1.00185.97 O +ATOM 33675 CB SER R 173 51.998 25.251 4.444 1.00200.02 C +ATOM 33676 OG SER R 173 51.766 26.635 4.329 1.00188.40 O +ATOM 33677 N SER R 174 53.387 26.888 6.990 1.00 91.42 N +ATOM 33678 CA SER R 174 52.992 27.913 7.966 1.00104.13 C +ATOM 33679 C SER R 174 52.976 29.238 7.267 1.00116.60 C +ATOM 33680 O SER R 174 53.905 29.551 6.509 1.00170.44 O +ATOM 33681 CB SER R 174 53.961 27.968 9.180 1.00104.13 C +ATOM 33682 OG SER R 174 53.478 28.810 10.239 1.00 57.07 O +ATOM 33683 N VAL R 175 51.959 30.042 7.553 1.00 95.87 N +ATOM 33684 CA VAL R 175 51.859 31.380 6.967 1.00 98.89 C +ATOM 33685 C VAL R 175 51.407 32.421 7.982 1.00107.59 C +ATOM 33686 O VAL R 175 50.599 32.143 8.860 1.00125.26 O +ATOM 33687 CB VAL R 175 50.884 31.411 5.771 1.00113.58 C +ATOM 33688 CG1 VAL R 175 51.393 30.516 4.648 1.00140.47 C +ATOM 33689 CG2 VAL R 175 49.492 30.968 6.178 1.00108.13 C +ATOM 33690 N ASN R 176 51.909 33.639 7.818 1.00135.03 N +ATOM 33691 CA ASN R 176 51.714 34.708 8.793 1.00157.43 C +ATOM 33692 C ASN R 176 51.185 35.991 8.130 1.00109.66 C +ATOM 33693 O ASN R 176 51.980 36.821 7.720 1.00135.54 O +ATOM 33694 CB ASN R 176 53.069 34.975 9.515 1.00174.18 C +ATOM 33695 CG ASN R 176 53.204 34.198 10.840 1.00138.43 C +ATOM 33696 OD1 ASN R 176 52.379 33.337 11.091 1.00186.98 O +ATOM 33697 ND2 ASN R 176 54.176 34.548 11.716 1.00 84.64 N +ATOM 33698 N THR R 177 49.877 36.192 8.143 1.00 77.94 N +ATOM 33699 CA THR R 177 49.283 37.374 7.534 1.00 89.41 C +ATOM 33700 C THR R 177 49.002 38.487 8.544 1.00110.64 C +ATOM 33701 O THR R 177 48.920 38.232 9.741 1.00137.29 O +ATOM 33702 CB THR R 177 47.979 37.026 6.800 1.00 98.40 C +ATOM 33703 OG1 THR R 177 46.958 36.692 7.740 1.00100.00 O +ATOM 33704 CG2 THR R 177 48.188 35.828 5.859 1.00129.65 C +ATOM 33705 N SER R 178 48.825 39.713 8.047 1.00141.68 N +ATOM 33706 CA SER R 178 48.628 40.904 8.896 1.00128.88 C +ATOM 33707 C SER R 178 47.745 41.948 8.216 1.00107.70 C +ATOM 33708 O SER R 178 47.647 42.004 6.997 1.00140.76 O +ATOM 33709 CB SER R 178 49.967 41.562 9.243 1.00103.43 C +ATOM 33710 OG SER R 178 49.759 42.856 9.795 1.00 92.66 O +ATOM 33711 N LYS R 179 47.080 42.761 9.016 1.00 99.35 N +ATOM 33712 CA LYS R 179 46.077 43.666 8.496 1.00115.83 C +ATOM 33713 C LYS R 179 45.881 44.840 9.441 1.00133.96 C +ATOM 33714 O LYS R 179 45.934 44.696 10.671 1.00221.10 O +ATOM 33715 CB LYS R 179 44.757 42.912 8.284 1.00137.30 C +ATOM 33716 CG LYS R 179 43.966 43.364 7.066 1.00141.22 C +ATOM 33717 CD LYS R 179 42.938 44.409 7.457 1.00109.44 C +ATOM 33718 CE LYS R 179 42.283 44.972 6.220 1.00108.18 C +ATOM 33719 NZ LYS R 179 41.506 46.192 6.542 1.00111.71 N +ATOM 33720 N THR R 180 45.634 46.000 8.863 1.00107.67 N +ATOM 33721 CA THR R 180 45.518 47.218 9.631 1.00118.65 C +ATOM 33722 C THR R 180 44.050 47.682 9.721 1.00115.95 C +ATOM 33723 O THR R 180 43.324 47.742 8.719 1.00129.48 O +ATOM 33724 CB THR R 180 46.413 48.335 9.058 1.00161.06 C +ATOM 33725 OG1 THR R 180 45.886 49.622 9.421 1.00225.78 O +ATOM 33726 CG2 THR R 180 46.501 48.241 7.537 1.00194.91 C +ATOM 33727 N ILE R 181 43.638 48.062 10.926 1.00129.25 N +ATOM 33728 CA ILE R 181 42.280 48.573 11.169 1.00151.03 C +ATOM 33729 C ILE R 181 42.281 50.111 11.263 1.00159.12 C +ATOM 33730 O ILE R 181 42.903 50.680 12.153 1.00137.78 O +ATOM 33731 CB ILE R 181 41.666 47.961 12.458 1.00141.23 C +ATOM 33732 CG1 ILE R 181 41.767 46.433 12.425 1.00145.95 C +ATOM 33733 CG2 ILE R 181 40.208 48.363 12.636 1.00111.26 C +ATOM 33734 CD1 ILE R 181 42.597 45.855 13.553 1.00160.62 C +ATOM 33735 N LEU R 182 41.563 50.760 10.343 1.00191.17 N +ATOM 33736 CA LEU R 182 41.503 52.226 10.251 1.00179.18 C +ATOM 33737 C LEU R 182 40.326 52.855 11.010 1.00147.39 C +ATOM 33738 O LEU R 182 39.190 52.377 10.943 1.00 78.74 O +ATOM 33739 CB LEU R 182 41.419 52.653 8.783 1.00191.69 C +ATOM 33740 CG LEU R 182 41.337 54.160 8.531 1.00185.34 C +ATOM 33741 CD1 LEU R 182 42.568 54.905 9.035 1.00146.81 C +ATOM 33742 CD2 LEU R 182 41.113 54.383 7.047 1.00199.31 C +ATOM 33743 N SER R 183 40.612 53.974 11.665 1.00150.44 N +ATOM 33744 CA SER R 183 39.588 54.771 12.321 1.00165.62 C +ATOM 33745 C SER R 183 39.857 56.260 12.092 1.00164.27 C +ATOM 33746 O SER R 183 41.012 56.697 12.128 1.00171.07 O +ATOM 33747 CB SER R 183 39.575 54.466 13.823 1.00205.27 C +ATOM 33748 OG SER R 183 39.809 53.086 14.073 1.00242.09 O +ATOM 33749 N TYR R 184 38.796 57.040 11.878 1.00154.24 N +ATOM 33750 CA TYR R 184 38.929 58.501 11.720 1.00126.25 C +ATOM 33751 C TYR R 184 37.679 59.318 12.103 1.00109.09 C +ATOM 33752 O TYR R 184 36.550 58.806 12.167 1.00 65.21 O +ATOM 33753 CB TYR R 184 39.360 58.880 10.298 1.00 95.58 C +ATOM 33754 CG TYR R 184 38.411 58.454 9.220 1.00 93.89 C +ATOM 33755 CD1 TYR R 184 37.257 59.183 8.943 1.00 92.31 C +ATOM 33756 CD2 TYR R 184 38.622 57.272 8.522 1.00115.59 C +ATOM 33757 CE1 TYR R 184 36.361 58.772 7.972 1.00118.32 C +ATOM 33758 CE2 TYR R 184 37.712 56.830 7.580 1.00145.06 C +ATOM 33759 CZ TYR R 184 36.596 57.598 7.287 1.00141.32 C +ATOM 33760 OH TYR R 184 35.674 57.130 6.365 1.00141.94 O +ATOM 33761 N GLU R 185 37.949 60.571 12.455 1.00109.92 N +ATOM 33762 CA GLU R 185 36.971 61.452 13.043 1.00124.09 C +ATOM 33763 C GLU R 185 37.075 62.829 12.435 1.00146.86 C +ATOM 33764 O GLU R 185 38.051 63.539 12.635 1.00145.16 O +ATOM 33765 CB GLU R 185 37.186 61.486 14.558 1.00156.87 C +ATOM 33766 CG GLU R 185 36.404 62.522 15.341 1.00164.39 C +ATOM 33767 CD GLU R 185 36.516 62.291 16.846 1.00165.12 C +ATOM 33768 OE1 GLU R 185 37.141 61.292 17.261 1.00152.10 O +ATOM 33769 OE2 GLU R 185 35.954 63.089 17.618 1.00145.26 O +ATOM 33770 N VAL R 186 36.080 63.169 11.624 1.00169.79 N +ATOM 33771 CA VAL R 186 36.016 64.459 10.949 1.00163.53 C +ATOM 33772 C VAL R 186 35.015 65.365 11.665 1.00144.62 C +ATOM 33773 O VAL R 186 33.951 64.912 12.084 1.00 91.35 O +ATOM 33774 CB VAL R 186 35.601 64.297 9.472 1.00162.74 C +ATOM 33775 CG1 VAL R 186 35.737 65.619 8.736 1.00191.90 C +ATOM 33776 CG2 VAL R 186 36.442 63.230 8.789 1.00166.52 C +ATOM 33777 N GLN R 187 35.378 66.636 11.825 1.00160.87 N +ATOM 33778 CA GLN R 187 34.544 67.577 12.568 1.00162.14 C +ATOM 33779 C GLN R 187 34.676 68.980 12.013 1.00173.31 C +ATOM 33780 O GLN R 187 35.784 69.434 11.719 1.00166.50 O +ATOM 33781 CB GLN R 187 34.962 67.589 14.043 1.00156.97 C +ATOM 33782 CG GLN R 187 34.313 66.531 14.912 1.00159.64 C +ATOM 33783 CD GLN R 187 35.092 66.274 16.187 1.00171.47 C +ATOM 33784 OE1 GLN R 187 35.648 67.198 16.781 1.00161.07 O +ATOM 33785 NE2 GLN R 187 35.171 65.004 16.594 1.00169.55 N +ATOM 33786 N ALA R 188 33.547 69.679 11.924 1.00157.56 N +ATOM 33787 CA ALA R 188 33.548 71.076 11.504 1.00137.91 C +ATOM 33788 C ALA R 188 32.516 71.882 12.288 1.00127.22 C +ATOM 33789 O ALA R 188 31.437 71.393 12.580 1.00 99.47 O +ATOM 33790 CB ALA R 188 33.284 71.172 10.013 1.00128.70 C +ATOM 33791 N GLY R 189 32.873 73.108 12.656 1.00135.92 N +ATOM 33792 CA GLY R 189 31.989 73.957 13.443 1.00149.71 C +ATOM 33793 C GLY R 189 32.117 75.427 13.087 1.00173.83 C +ATOM 33794 O GLY R 189 33.223 75.931 12.889 1.00167.57 O +ATOM 33795 N VAL R 190 30.982 76.120 13.032 1.00182.76 N +ATOM 33796 CA VAL R 190 30.956 77.561 12.778 1.00180.65 C +ATOM 33797 C VAL R 190 30.400 78.310 13.992 1.00177.98 C +ATOM 33798 O VAL R 190 29.431 77.868 14.614 1.00127.50 O +ATOM 33799 CB VAL R 190 30.096 77.892 11.547 1.00182.04 C +ATOM 33800 CG1 VAL R 190 30.287 79.343 11.147 1.00170.91 C +ATOM 33801 CG2 VAL R 190 30.431 76.953 10.385 1.00183.03 C +ATOM 33802 N PHE R 191 31.055 79.408 14.368 1.00205.91 N +ATOM 33803 CA PHE R 191 30.766 80.076 15.643 1.00234.41 C +ATOM 33804 C PHE R 191 30.648 81.582 15.432 1.00199.51 C +ATOM 33805 O PHE R 191 31.527 82.181 14.810 1.00192.47 O +ATOM 33806 CB PHE R 191 31.861 79.754 16.684 1.00243.32 C +ATOM 33807 CG PHE R 191 31.425 79.951 18.115 1.00225.43 C +ATOM 33808 CD1 PHE R 191 31.236 81.230 18.628 1.00190.71 C +ATOM 33809 CD2 PHE R 191 31.223 78.858 18.952 1.00204.47 C +ATOM 33810 CE1 PHE R 191 30.854 81.416 19.945 1.00167.41 C +ATOM 33811 CE2 PHE R 191 30.825 79.039 20.265 1.00200.57 C +ATOM 33812 CZ PHE R 191 30.650 80.320 20.765 1.00179.71 C +ATOM 33813 N LEU R 200 25.339 82.653 17.178 1.00184.91 N +ATOM 33814 CA LEU R 200 25.320 81.577 16.186 1.00215.34 C +ATOM 33815 C LEU R 200 26.422 80.558 16.441 1.00217.68 C +ATOM 33816 O LEU R 200 27.609 80.862 16.283 1.00182.88 O +ATOM 33817 CB LEU R 200 25.475 82.115 14.755 1.00209.28 C +ATOM 33818 CG LEU R 200 25.657 81.021 13.681 1.00179.22 C +ATOM 33819 CD1 LEU R 200 24.343 80.785 12.951 1.00158.60 C +ATOM 33820 CD2 LEU R 200 26.790 81.323 12.700 1.00164.28 C +ATOM 33821 N GLU R 201 26.016 79.343 16.806 1.00207.54 N +ATOM 33822 CA GLU R 201 26.882 78.175 16.701 1.00174.51 C +ATOM 33823 C GLU R 201 26.262 77.132 15.783 1.00139.90 C +ATOM 33824 O GLU R 201 25.039 77.009 15.712 1.00113.32 O +ATOM 33825 CB GLU R 201 27.141 77.563 18.077 1.00178.03 C +ATOM 33826 CG GLU R 201 28.377 76.673 18.104 1.00182.36 C +ATOM 33827 CD GLU R 201 28.654 76.063 19.467 1.00181.32 C +ATOM 33828 OE1 GLU R 201 28.666 76.809 20.470 1.00202.56 O +ATOM 33829 OE2 GLU R 201 28.856 74.833 19.536 1.00171.14 O +ATOM 33830 N GLY R 202 27.107 76.382 15.083 1.00123.19 N +ATOM 33831 CA GLY R 202 26.653 75.256 14.265 1.00133.73 C +ATOM 33832 C GLY R 202 27.759 74.232 14.085 1.00137.82 C +ATOM 33833 O GLY R 202 28.863 74.569 13.652 1.00118.77 O +ATOM 33834 N GLU R 203 27.459 72.972 14.381 1.00138.53 N +ATOM 33835 CA GLU R 203 28.473 71.923 14.328 1.00134.65 C +ATOM 33836 C GLU R 203 28.031 70.675 13.566 1.00118.00 C +ATOM 33837 O GLU R 203 26.909 70.191 13.728 1.00 71.58 O +ATOM 33838 CB GLU R 203 28.886 71.537 15.746 1.00158.92 C +ATOM 33839 CG GLU R 203 29.623 72.653 16.486 1.00171.90 C +ATOM 33840 CD GLU R 203 30.138 72.254 17.865 1.00207.90 C +ATOM 33841 OE1 GLU R 203 29.789 71.147 18.344 1.00228.99 O +ATOM 33842 OE2 GLU R 203 30.888 73.059 18.478 1.00221.94 O +ATOM 33843 N VAL R 204 28.945 70.150 12.757 1.00135.38 N +ATOM 33844 CA VAL R 204 28.794 68.851 12.110 1.00170.75 C +ATOM 33845 C VAL R 204 29.974 67.959 12.499 1.00191.78 C +ATOM 33846 O VAL R 204 31.126 68.397 12.509 1.00184.04 O +ATOM 33847 CB VAL R 204 28.713 68.997 10.570 1.00156.25 C +ATOM 33848 CG1 VAL R 204 28.926 67.663 9.861 1.00146.70 C +ATOM 33849 CG2 VAL R 204 27.370 69.596 10.182 1.00148.03 C +ATOM 33850 N GLY R 205 29.670 66.704 12.825 1.00179.66 N +ATOM 33851 CA GLY R 205 30.695 65.714 13.131 1.00148.61 C +ATOM 33852 C GLY R 205 30.410 64.361 12.499 1.00121.49 C +ATOM 33853 O GLY R 205 29.256 64.000 12.286 1.00 81.33 O +ATOM 33854 N TYR R 206 31.471 63.618 12.193 1.00141.56 N +ATOM 33855 CA TYR R 206 31.351 62.249 11.685 1.00162.77 C +ATOM 33856 C TYR R 206 32.536 61.403 12.141 1.00179.57 C +ATOM 33857 O TYR R 206 33.664 61.883 12.158 1.00193.06 O +ATOM 33858 CB TYR R 206 31.294 62.249 10.153 1.00173.75 C +ATOM 33859 CG TYR R 206 31.237 60.859 9.531 1.00163.19 C +ATOM 33860 CD1 TYR R 206 30.058 60.103 9.552 1.00125.24 C +ATOM 33861 CD2 TYR R 206 32.359 60.311 8.913 1.00152.63 C +ATOM 33862 CE1 TYR R 206 29.991 58.854 8.962 1.00 89.55 C +ATOM 33863 CE2 TYR R 206 32.301 59.068 8.316 1.00129.89 C +ATOM 33864 CZ TYR R 206 31.118 58.344 8.346 1.00111.30 C +ATOM 33865 OH TYR R 206 31.102 57.089 7.774 1.00152.05 O +ATOM 33866 N THR R 207 32.287 60.135 12.462 1.00152.79 N +ATOM 33867 CA THR R 207 33.364 59.221 12.848 1.00145.57 C +ATOM 33868 C THR R 207 33.180 57.835 12.219 1.00118.32 C +ATOM 33869 O THR R 207 32.060 57.308 12.166 1.00 71.09 O +ATOM 33870 CB THR R 207 33.429 59.056 14.378 1.00163.38 C +ATOM 33871 OG1 THR R 207 32.197 58.498 14.855 1.00167.25 O +ATOM 33872 CG2 THR R 207 33.649 60.387 15.058 1.00163.65 C +ATOM 33873 N SER R 208 34.275 57.241 11.738 1.00104.18 N +ATOM 33874 CA SER R 208 34.206 55.905 11.125 1.00118.24 C +ATOM 33875 C SER R 208 35.311 54.979 11.605 1.00143.73 C +ATOM 33876 O SER R 208 36.497 55.308 11.515 1.00107.32 O +ATOM 33877 CB SER R 208 34.245 55.992 9.597 1.00124.39 C +ATOM 33878 OG SER R 208 34.306 54.706 8.991 1.00 80.14 O +ATOM 33879 N ASN R 209 34.896 53.806 12.075 1.00179.67 N +ATOM 33880 CA ASN R 209 35.811 52.735 12.449 1.00185.99 C +ATOM 33881 C ASN R 209 35.654 51.553 11.520 1.00177.19 C +ATOM 33882 O ASN R 209 34.531 51.165 11.196 1.00110.06 O +ATOM 33883 CB ASN R 209 35.516 52.254 13.864 1.00174.30 C +ATOM 33884 CG ASN R 209 35.882 53.275 14.906 1.00160.18 C +ATOM 33885 OD1 ASN R 209 37.038 53.375 15.312 1.00180.08 O +ATOM 33886 ND2 ASN R 209 34.893 54.013 15.372 1.00132.39 N +ATOM 33887 N GLU R 210 36.777 50.966 11.114 1.00171.08 N +ATOM 33888 CA GLU R 210 36.738 49.682 10.432 1.00141.95 C +ATOM 33889 C GLU R 210 36.295 48.647 11.442 1.00141.61 C +ATOM 33890 O GLU R 210 36.666 48.701 12.619 1.00150.20 O +ATOM 33891 CB GLU R 210 38.106 49.313 9.871 1.00122.36 C +ATOM 33892 CG GLU R 210 38.086 48.742 8.464 1.00116.29 C +ATOM 33893 CD GLU R 210 39.462 48.797 7.803 1.00187.40 C +ATOM 33894 OE1 GLU R 210 40.323 49.667 8.156 1.00292.39 O +ATOM 33895 OE2 GLU R 210 39.716 47.948 6.924 1.00258.02 O +ATOM 33896 N PRO R 211 35.460 47.712 11.005 1.00135.29 N +ATOM 33897 CA PRO R 211 35.164 46.590 11.874 1.00157.54 C +ATOM 33898 C PRO R 211 36.363 45.633 12.020 1.00176.38 C +ATOM 33899 O PRO R 211 36.900 45.142 11.024 1.00162.24 O +ATOM 33900 CB PRO R 211 33.989 45.900 11.166 1.00182.74 C +ATOM 33901 CG PRO R 211 33.452 46.905 10.209 1.00156.43 C +ATOM 33902 CD PRO R 211 34.652 47.688 9.783 1.00149.59 C +ATOM 33903 N VAL R 212 36.757 45.367 13.264 1.00159.27 N +ATOM 33904 CA VAL R 212 37.857 44.443 13.553 1.00121.65 C +ATOM 33905 C VAL R 212 37.459 43.066 13.028 1.00 99.74 C +ATOM 33906 O VAL R 212 38.264 42.309 12.514 1.00 65.65 O +ATOM 33907 CB VAL R 212 38.157 44.389 15.083 1.00 94.20 C +ATOM 33908 CG1 VAL R 212 39.397 43.533 15.344 1.00 74.89 C +ATOM 33909 CG2 VAL R 212 38.336 45.792 15.659 1.00101.51 C +ATOM 33910 N MET R 213 36.214 42.725 13.327 1.00 93.75 N +ATOM 33911 CA MET R 213 35.512 41.590 12.771 1.00 87.16 C +ATOM 33912 C MET R 213 35.926 41.333 11.332 1.00 76.95 C +ATOM 33913 O MET R 213 36.202 40.208 10.924 1.00 86.98 O +ATOM 33914 CB MET R 213 34.019 41.971 12.890 1.00118.97 C +ATOM 33915 CG MET R 213 32.966 40.977 12.467 1.00135.75 C +ATOM 33916 SD MET R 213 31.351 41.804 12.740 1.00154.10 S +ATOM 33917 CE MET R 213 30.905 41.941 11.025 1.00165.50 C +ATOM 33918 N LEU R 214 35.874 42.388 10.539 1.00101.11 N +ATOM 33919 CA LEU R 214 35.862 42.282 9.080 1.00126.54 C +ATOM 33920 C LEU R 214 37.303 42.207 8.623 1.00108.72 C +ATOM 33921 O LEU R 214 37.605 41.599 7.589 1.00101.13 O +ATOM 33922 CB LEU R 214 35.144 43.499 8.446 1.00132.64 C +ATOM 33923 CG LEU R 214 34.202 43.292 7.258 1.00114.73 C +ATOM 33924 CD1 LEU R 214 33.042 42.347 7.589 1.00117.02 C +ATOM 33925 CD2 LEU R 214 33.673 44.639 6.772 1.00107.55 C +ATOM 33926 N CYS R 215 38.182 42.788 9.425 1.00 79.05 N +ATOM 33927 CA CYS R 215 39.591 42.751 9.114 1.00100.81 C +ATOM 33928 C CYS R 215 40.107 41.344 9.383 1.00 88.90 C +ATOM 33929 O CYS R 215 41.021 40.828 8.675 1.00 74.86 O +ATOM 33930 CB CYS R 215 40.340 43.775 9.970 1.00127.32 C +ATOM 33931 SG CYS R 215 39.913 45.479 9.600 1.00152.42 S +ATOM 33932 N LEU R 216 39.617 40.774 10.480 1.00 73.23 N +ATOM 33933 CA LEU R 216 40.038 39.435 10.855 1.00 98.06 C +ATOM 33934 C LEU R 216 39.653 38.496 9.726 1.00117.28 C +ATOM 33935 O LEU R 216 40.460 37.693 9.259 1.00104.28 O +ATOM 33936 CB LEU R 216 39.364 39.017 12.159 1.00117.54 C +ATOM 33937 CG LEU R 216 39.644 37.570 12.609 1.00116.48 C +ATOM 33938 CD1 LEU R 216 41.135 37.272 12.783 1.00 92.52 C +ATOM 33939 CD2 LEU R 216 38.888 37.265 13.902 1.00 92.98 C +ATOM 33940 N MET R 217 38.427 38.662 9.240 1.00150.96 N +ATOM 33941 CA MET R 217 37.905 37.794 8.186 1.00152.28 C +ATOM 33942 C MET R 217 38.731 37.920 6.907 1.00114.92 C +ATOM 33943 O MET R 217 39.165 36.925 6.350 1.00 88.98 O +ATOM 33944 CB MET R 217 36.430 38.117 7.907 1.00195.47 C +ATOM 33945 CG MET R 217 35.558 36.881 7.753 1.00213.72 C +ATOM 33946 SD MET R 217 35.940 35.963 6.248 1.00235.45 S +ATOM 33947 CE MET R 217 35.001 34.455 6.477 1.00272.88 C +ATOM 33948 N SER R 218 39.005 39.162 6.512 1.00 90.12 N +ATOM 33949 CA SER R 218 39.840 39.445 5.360 1.00 94.40 C +ATOM 33950 C SER R 218 41.209 38.747 5.453 1.00109.58 C +ATOM 33951 O SER R 218 41.655 38.079 4.517 1.00107.36 O +ATOM 33952 CB SER R 218 40.034 40.963 5.221 1.00 92.51 C +ATOM 33953 OG SER R 218 40.640 41.287 3.976 1.00125.57 O +ATOM 33954 N ALA R 219 41.889 38.943 6.578 1.00107.04 N +ATOM 33955 CA ALA R 219 43.238 38.436 6.741 1.00101.24 C +ATOM 33956 C ALA R 219 43.245 36.886 6.686 1.00139.09 C +ATOM 33957 O ALA R 219 44.207 36.256 6.216 1.00106.76 O +ATOM 33958 CB ALA R 219 43.821 38.960 8.046 1.00 85.56 C +ATOM 33959 N ILE R 220 42.185 36.264 7.201 1.00172.42 N +ATOM 33960 CA ILE R 220 42.106 34.796 7.217 1.00164.79 C +ATOM 33961 C ILE R 220 41.988 34.299 5.781 1.00129.53 C +ATOM 33962 O ILE R 220 42.574 33.282 5.414 1.00 97.89 O +ATOM 33963 CB ILE R 220 40.935 34.289 8.111 1.00154.12 C +ATOM 33964 CG1 ILE R 220 41.269 34.540 9.585 1.00165.41 C +ATOM 33965 CG2 ILE R 220 40.665 32.803 7.874 1.00121.51 C +ATOM 33966 CD1 ILE R 220 40.084 34.461 10.514 1.00166.14 C +ATOM 33967 N GLU R 221 41.185 34.997 4.986 1.00111.18 N +ATOM 33968 CA GLU R 221 40.994 34.619 3.592 1.00101.92 C +ATOM 33969 C GLU R 221 42.342 34.645 2.892 1.00 95.97 C +ATOM 33970 O GLU R 221 42.728 33.690 2.200 1.00 85.71 O +ATOM 33971 CB GLU R 221 40.007 35.589 2.926 1.00109.79 C +ATOM 33972 CG GLU R 221 38.552 35.347 3.311 1.00130.52 C +ATOM 33973 CD GLU R 221 37.620 36.514 3.025 1.00134.91 C +ATOM 33974 OE1 GLU R 221 38.043 37.694 3.121 1.00103.50 O +ATOM 33975 OE2 GLU R 221 36.461 36.236 2.626 1.00173.63 O +ATOM 33976 N THR R 222 43.034 35.769 3.055 1.00 93.60 N +ATOM 33977 CA THR R 222 44.356 35.983 2.474 1.00 91.95 C +ATOM 33978 C THR R 222 45.272 34.823 2.835 1.00 95.48 C +ATOM 33979 O THR R 222 45.992 34.292 1.975 1.00 73.94 O +ATOM 33980 CB THR R 222 44.969 37.304 3.008 1.00 99.61 C +ATOM 33981 OG1 THR R 222 44.292 38.439 2.440 1.00 66.12 O +ATOM 33982 CG2 THR R 222 46.494 37.370 2.730 1.00 93.61 C +ATOM 33983 N GLY R 223 45.263 34.461 4.118 1.00106.21 N +ATOM 33984 CA GLY R 223 46.062 33.339 4.598 1.00132.41 C +ATOM 33985 C GLY R 223 45.731 32.050 3.858 1.00152.81 C +ATOM 33986 O GLY R 223 46.623 31.240 3.565 1.00136.72 O +ATOM 33987 N VAL R 224 44.442 31.835 3.584 1.00146.00 N +ATOM 33988 CA VAL R 224 44.001 30.593 2.943 1.00117.84 C +ATOM 33989 C VAL R 224 44.572 30.546 1.536 1.00136.51 C +ATOM 33990 O VAL R 224 45.052 29.515 1.080 1.00128.34 O +ATOM 33991 CB VAL R 224 42.471 30.490 2.881 1.00 97.89 C +ATOM 33992 CG1 VAL R 224 42.074 29.301 2.027 1.00 92.59 C +ATOM 33993 CG2 VAL R 224 41.895 30.357 4.275 1.00107.60 C +ATOM 33994 N ILE R 225 44.560 31.693 0.859 1.00150.34 N +ATOM 33995 CA ILE R 225 45.133 31.776 -0.489 1.00126.77 C +ATOM 33996 C ILE R 225 46.621 31.427 -0.470 1.00117.75 C +ATOM 33997 O ILE R 225 47.039 30.554 -1.224 1.00 79.57 O +ATOM 33998 CB ILE R 225 44.931 33.164 -1.129 1.00102.61 C +ATOM 33999 CG1 ILE R 225 43.443 33.400 -1.411 1.00 92.15 C +ATOM 34000 CG2 ILE R 225 45.710 33.261 -2.427 1.00 86.62 C +ATOM 34001 CD1 ILE R 225 43.090 34.856 -1.624 1.00 92.04 C +ATOM 34002 N PHE R 226 47.393 32.087 0.409 1.00 98.67 N +ATOM 34003 CA PHE R 226 48.834 31.824 0.536 1.00 84.47 C +ATOM 34004 C PHE R 226 49.102 30.352 0.842 1.00109.36 C +ATOM 34005 O PHE R 226 50.099 29.793 0.396 1.00 82.72 O +ATOM 34006 CB PHE R 226 49.465 32.693 1.612 1.00 77.12 C +ATOM 34007 CG PHE R 226 49.768 34.111 1.174 1.00 91.49 C +ATOM 34008 CD1 PHE R 226 50.648 34.361 0.132 1.00 99.98 C +ATOM 34009 CD2 PHE R 226 49.240 35.206 1.871 1.00 93.27 C +ATOM 34010 CE1 PHE R 226 50.946 35.665 -0.257 1.00 99.32 C +ATOM 34011 CE2 PHE R 226 49.559 36.505 1.512 1.00 92.77 C +ATOM 34012 CZ PHE R 226 50.402 36.736 0.435 1.00104.14 C +ATOM 34013 N LEU R 227 48.178 29.706 1.558 1.00154.88 N +ATOM 34014 CA LEU R 227 48.300 28.259 1.849 1.00155.98 C +ATOM 34015 C LEU R 227 48.148 27.448 0.603 1.00138.48 C +ATOM 34016 O LEU R 227 48.894 26.503 0.396 1.00121.67 O +ATOM 34017 CB LEU R 227 47.226 27.757 2.821 1.00151.55 C +ATOM 34018 CG LEU R 227 47.672 27.224 4.180 1.00165.56 C +ATOM 34019 CD1 LEU R 227 48.918 27.934 4.567 1.00162.14 C +ATOM 34020 CD2 LEU R 227 46.685 27.266 5.350 1.00181.75 C +ATOM 34021 N ILE R 228 47.129 27.779 -0.191 1.00124.52 N +ATOM 34022 CA ILE R 228 46.822 27.006 -1.393 1.00119.11 C +ATOM 34023 C ILE R 228 47.962 27.154 -2.375 1.00127.31 C +ATOM 34024 O ILE R 228 48.461 26.168 -2.911 1.00 98.88 O +ATOM 34025 CB ILE R 228 45.518 27.459 -2.083 1.00106.46 C +ATOM 34026 CG1 ILE R 228 44.310 27.203 -1.181 1.00118.10 C +ATOM 34027 CG2 ILE R 228 45.322 26.690 -3.381 1.00 91.49 C +ATOM 34028 CD1 ILE R 228 43.048 27.924 -1.599 1.00 98.99 C +ATOM 34029 N ASN R 229 48.402 28.396 -2.572 1.00146.78 N +ATOM 34030 CA ASN R 229 49.503 28.689 -3.491 1.00154.47 C +ATOM 34031 C ASN R 229 50.788 27.977 -3.060 1.00166.60 C +ATOM 34032 O ASN R 229 51.458 27.338 -3.872 1.00148.96 O +ATOM 34033 CB ASN R 229 49.734 30.202 -3.565 1.00148.67 C +ATOM 34034 CG ASN R 229 50.539 30.618 -4.778 1.00170.53 C +ATOM 34035 OD1 ASN R 229 50.619 29.891 -5.769 1.00165.02 O +ATOM 34036 ND2 ASN R 229 51.184 31.775 -4.682 1.00194.56 N +ATOM 34037 N ASP R 230 51.079 28.037 -1.761 1.00183.02 N +ATOM 34038 CA ASP R 230 52.227 27.356 -1.194 1.00179.33 C +ATOM 34039 C ASP R 230 52.126 25.843 -1.440 1.00195.54 C +ATOM 34040 O ASP R 230 53.117 25.182 -1.758 1.00181.94 O +ATOM 34041 CB ASP R 230 52.330 27.659 0.304 1.00161.29 C +ATOM 34042 CG ASP R 230 53.603 27.123 0.919 1.00190.38 C +ATOM 34043 OD1 ASP R 230 54.681 27.678 0.595 1.00116.44 O +ATOM 34044 OD2 ASP R 230 53.535 26.097 1.672 1.00271.62 O +ATOM 34045 N GLY R 231 50.931 25.289 -1.259 1.00189.43 N +ATOM 34046 CA GLY R 231 50.726 23.857 -1.443 1.00184.57 C +ATOM 34047 C GLY R 231 50.897 23.450 -2.895 1.00165.01 C +ATOM 34048 O GLY R 231 51.356 22.335 -3.193 1.00106.59 O +ATOM 34049 N ILE R 232 50.473 24.333 -3.799 1.00157.95 N +ATOM 34050 CA ILE R 232 50.638 24.102 -5.231 1.00144.39 C +ATOM 34051 C ILE R 232 52.121 23.986 -5.547 1.00132.52 C +ATOM 34052 O ILE R 232 52.542 23.033 -6.212 1.00120.46 O +ATOM 34053 CB ILE R 232 49.992 25.226 -6.074 1.00142.00 C +ATOM 34054 CG1 ILE R 232 48.462 25.091 -6.040 1.00139.40 C +ATOM 34055 CG2 ILE R 232 50.503 25.197 -7.517 1.00152.89 C +ATOM 34056 CD1 ILE R 232 47.725 26.345 -6.456 1.00142.91 C +ATOM 34057 N ASP R 233 52.897 24.957 -5.068 1.00133.01 N +ATOM 34058 CA ASP R 233 54.342 24.973 -5.275 1.00139.29 C +ATOM 34059 C ASP R 233 54.966 23.690 -4.741 1.00144.46 C +ATOM 34060 O ASP R 233 55.777 23.051 -5.422 1.00164.51 O +ATOM 34061 CB ASP R 233 54.980 26.188 -4.578 1.00139.58 C +ATOM 34062 CG ASP R 233 54.541 27.526 -5.180 1.00137.21 C +ATOM 34063 OD1 ASP R 233 53.644 27.535 -6.048 1.00133.21 O +ATOM 34064 OD2 ASP R 233 55.159 28.561 -4.834 1.00110.44 O +ATOM 34065 N ARG R 234 54.596 23.313 -3.519 1.00151.91 N +ATOM 34066 CA ARG R 234 55.251 22.196 -2.817 1.00157.73 C +ATOM 34067 C ARG R 234 54.697 20.814 -3.170 1.00120.53 C +ATOM 34068 O ARG R 234 55.223 19.795 -2.705 1.00 82.97 O +ATOM 34069 CB ARG R 234 55.163 22.395 -1.306 1.00162.56 C +ATOM 34070 CG ARG R 234 56.081 23.490 -0.818 1.00153.32 C +ATOM 34071 CD ARG R 234 55.652 24.034 0.519 1.00125.23 C +ATOM 34072 NE ARG R 234 56.546 25.120 0.898 1.00142.35 N +ATOM 34073 CZ ARG R 234 57.263 25.154 2.021 1.00157.63 C +ATOM 34074 NH1 ARG R 234 57.147 24.188 2.925 1.00121.85 N +ATOM 34075 NH2 ARG R 234 58.079 26.186 2.247 1.00180.90 N +ATOM 34076 N GLY R 235 53.695 20.783 -4.046 1.00100.51 N +ATOM 34077 CA GLY R 235 53.211 19.525 -4.594 1.00102.62 C +ATOM 34078 C GLY R 235 52.323 18.808 -3.613 1.00104.70 C +ATOM 34079 O GLY R 235 52.292 17.574 -3.586 1.00 89.33 O +ATOM 34080 N LEU R 236 51.594 19.571 -2.803 1.00125.04 N +ATOM 34081 CA LEU R 236 50.525 18.979 -1.979 1.00147.13 C +ATOM 34082 C LEU R 236 49.336 18.649 -2.873 1.00122.22 C +ATOM 34083 O LEU R 236 48.800 17.540 -2.829 1.00 93.73 O +ATOM 34084 CB LEU R 236 50.076 19.912 -0.840 1.00139.17 C +ATOM 34085 CG LEU R 236 50.896 19.914 0.461 1.00121.81 C +ATOM 34086 CD1 LEU R 236 52.167 20.735 0.291 1.00129.84 C +ATOM 34087 CD2 LEU R 236 50.068 20.465 1.606 1.00110.14 C +ATOM 34088 N TRP R 237 48.945 19.615 -3.689 1.00114.47 N +ATOM 34089 CA TRP R 237 47.797 19.451 -4.567 1.00152.50 C +ATOM 34090 C TRP R 237 48.090 20.065 -5.935 1.00182.78 C +ATOM 34091 O TRP R 237 49.054 20.830 -6.088 1.00219.19 O +ATOM 34092 CB TRP R 237 46.553 20.079 -3.933 1.00140.51 C +ATOM 34093 CG TRP R 237 46.858 21.269 -3.109 1.00142.61 C +ATOM 34094 CD1 TRP R 237 47.299 22.478 -3.556 1.00168.92 C +ATOM 34095 CD2 TRP R 237 46.754 21.382 -1.686 1.00143.25 C +ATOM 34096 NE1 TRP R 237 47.483 23.336 -2.500 1.00161.89 N +ATOM 34097 CE2 TRP R 237 47.138 22.692 -1.342 1.00148.09 C +ATOM 34098 CE3 TRP R 237 46.351 20.512 -0.672 1.00151.40 C +ATOM 34099 CZ2 TRP R 237 47.147 23.148 -0.029 1.00136.67 C +ATOM 34100 CZ3 TRP R 237 46.362 20.972 0.638 1.00152.21 C +ATOM 34101 CH2 TRP R 237 46.768 22.273 0.946 1.00137.76 C +ATOM 34102 N ASP R 238 47.264 19.718 -6.924 1.00181.19 N +ATOM 34103 CA ASP R 238 47.517 20.095 -8.312 1.00151.31 C +ATOM 34104 C ASP R 238 46.317 20.761 -8.978 1.00144.55 C +ATOM 34105 O ASP R 238 45.160 20.440 -8.691 1.00111.08 O +ATOM 34106 CB ASP R 238 47.947 18.883 -9.132 1.00120.60 C +ATOM 34107 CG ASP R 238 49.173 18.193 -8.550 1.00125.40 C +ATOM 34108 OD1 ASP R 238 49.018 17.426 -7.592 1.00 86.84 O +ATOM 34109 OD2 ASP R 238 50.295 18.409 -9.054 1.00164.33 O +ATOM 34110 N LEU R 239 46.627 21.692 -9.875 1.00135.03 N +ATOM 34111 CA LEU R 239 45.635 22.486 -10.568 1.00130.28 C +ATOM 34112 C LEU R 239 45.015 21.641 -11.715 1.00155.92 C +ATOM 34113 O LEU R 239 45.667 20.753 -12.309 1.00154.40 O +ATOM 34114 CB LEU R 239 46.268 23.853 -10.977 1.00118.72 C +ATOM 34115 CG LEU R 239 45.420 25.081 -10.649 1.00123.23 C +ATOM 34116 CD1 LEU R 239 46.120 26.359 -11.068 1.00121.68 C +ATOM 34117 CD2 LEU R 239 44.057 25.001 -11.336 1.00120.52 C +ATOM 34118 N GLN R 240 43.701 21.790 -11.903 1.00159.04 N +ATOM 34119 CA GLN R 240 43.015 21.169 -13.041 1.00151.24 C +ATOM 34120 C GLN R 240 43.743 21.523 -14.337 1.00146.88 C +ATOM 34121 O GLN R 240 44.158 20.642 -15.096 1.00111.64 O +ATOM 34122 CB GLN R 240 41.547 21.644 -13.107 1.00143.39 C +ATOM 34123 CG GLN R 240 40.706 20.912 -14.142 1.00128.40 C +ATOM 34124 CD GLN R 240 40.558 19.438 -13.797 1.00137.94 C +ATOM 34125 OE1 GLN R 240 39.704 19.063 -12.984 1.00186.19 O +ATOM 34126 NE2 GLN R 240 41.398 18.592 -14.396 1.00112.41 N +ATOM 34127 N ASN R 241 43.871 22.825 -14.580 1.00157.36 N +ATOM 34128 CA ASN R 241 44.542 23.346 -15.766 1.00151.57 C +ATOM 34129 C ASN R 241 45.923 23.862 -15.422 1.00155.04 C +ATOM 34130 O ASN R 241 46.057 24.906 -14.755 1.00183.81 O +ATOM 34131 CB ASN R 241 43.727 24.490 -16.369 1.00147.84 C +ATOM 34132 CG ASN R 241 42.916 24.058 -17.569 1.00166.19 C +ATOM 34133 OD1 ASN R 241 43.312 24.308 -18.706 1.00159.64 O +ATOM 34134 ND2 ASN R 241 41.800 23.368 -17.330 1.00179.66 N +ATOM 34135 N LYS R 242 46.948 23.150 -15.889 1.00133.64 N +ATOM 34136 CA LYS R 242 48.329 23.551 -15.624 1.00141.45 C +ATOM 34137 C LYS R 242 48.625 24.886 -16.310 1.00152.19 C +ATOM 34138 O LYS R 242 49.471 25.665 -15.850 1.00113.56 O +ATOM 34139 CB LYS R 242 49.304 22.465 -16.088 1.00123.37 C +ATOM 34140 CG LYS R 242 48.939 21.067 -15.612 1.00122.58 C +ATOM 34141 CD LYS R 242 50.094 20.398 -14.882 1.00131.45 C +ATOM 34142 CE LYS R 242 49.615 19.757 -13.584 1.00157.02 C +ATOM 34143 NZ LYS R 242 50.677 18.959 -12.914 1.00154.73 N +ATOM 34144 N ALA R 243 47.867 25.149 -17.379 1.00180.41 N +ATOM 34145 CA ALA R 243 47.891 26.422 -18.098 1.00185.09 C +ATOM 34146 C ALA R 243 47.455 27.587 -17.209 1.00188.34 C +ATOM 34147 O ALA R 243 47.739 28.747 -17.526 1.00202.43 O +ATOM 34148 CB ALA R 243 46.990 26.345 -19.327 1.00171.93 C +ATOM 34149 N GLU R 244 46.753 27.285 -16.113 1.00157.32 N +ATOM 34150 CA GLU R 244 46.249 28.335 -15.235 1.00140.85 C +ATOM 34151 C GLU R 244 47.211 28.642 -14.093 1.00143.26 C +ATOM 34152 O GLU R 244 46.852 29.373 -13.183 1.00115.44 O +ATOM 34153 CB GLU R 244 44.881 27.959 -14.669 1.00137.00 C +ATOM 34154 CG GLU R 244 43.751 28.040 -15.675 1.00150.13 C +ATOM 34155 CD GLU R 244 42.379 27.924 -15.030 1.00166.65 C +ATOM 34156 OE1 GLU R 244 41.975 26.799 -14.677 1.00160.04 O +ATOM 34157 OE2 GLU R 244 41.697 28.965 -14.893 1.00170.24 O +ATOM 34158 N ARG R 245 48.442 28.155 -14.194 1.00135.62 N +ATOM 34159 CA ARG R 245 49.472 28.470 -13.211 1.00137.02 C +ATOM 34160 C ARG R 245 49.775 29.971 -13.131 1.00155.62 C +ATOM 34161 O ARG R 245 50.103 30.482 -12.060 1.00155.48 O +ATOM 34162 CB ARG R 245 50.755 27.693 -13.513 1.00136.60 C +ATOM 34163 CG ARG R 245 51.846 27.866 -12.468 1.00145.67 C +ATOM 34164 CD ARG R 245 53.051 26.994 -12.779 1.00154.52 C +ATOM 34165 NE ARG R 245 53.086 25.792 -11.952 1.00164.84 N +ATOM 34166 CZ ARG R 245 53.261 25.796 -10.635 1.00167.75 C +ATOM 34167 NH1 ARG R 245 53.419 26.943 -9.988 1.00148.70 N +ATOM 34168 NH2 ARG R 245 53.278 24.654 -9.962 1.00180.01 N +ATOM 34169 N GLN R 246 49.670 30.673 -14.258 1.00182.07 N +ATOM 34170 CA GLN R 246 49.987 32.105 -14.295 1.00172.02 C +ATOM 34171 C GLN R 246 48.737 32.955 -14.108 1.00158.06 C +ATOM 34172 O GLN R 246 48.699 34.112 -14.534 1.00214.71 O +ATOM 34173 CB GLN R 246 50.721 32.479 -15.598 1.00162.15 C +ATOM 34174 CG GLN R 246 52.153 31.971 -15.688 1.00143.04 C +ATOM 34175 CD GLN R 246 52.223 30.488 -15.993 1.00166.26 C +ATOM 34176 OE1 GLN R 246 51.504 29.984 -16.864 1.00179.30 O +ATOM 34177 NE2 GLN R 246 53.090 29.776 -15.279 1.00176.88 N +ATOM 34178 N ASN R 247 47.698 32.353 -13.534 1.00114.87 N +ATOM 34179 CA ASN R 247 46.506 33.083 -13.114 1.00137.28 C +ATOM 34180 C ASN R 247 46.883 34.407 -12.439 1.00157.55 C +ATOM 34181 O ASN R 247 47.821 34.449 -11.630 1.00151.33 O +ATOM 34182 CB ASN R 247 45.721 32.216 -12.131 1.00140.88 C +ATOM 34183 CG ASN R 247 44.255 32.568 -12.081 1.00128.87 C +ATOM 34184 OD1 ASN R 247 43.764 33.128 -11.087 1.00128.54 O +ATOM 34185 ND2 ASN R 247 43.543 32.224 -13.139 1.00118.44 N +ATOM 34186 N ASP R 248 46.125 35.469 -12.730 1.00162.69 N +ATOM 34187 CA ASP R 248 46.401 36.810 -12.171 1.00198.64 C +ATOM 34188 C ASP R 248 46.532 36.789 -10.642 1.00215.38 C +ATOM 34189 O ASP R 248 47.463 37.372 -10.060 1.00239.37 O +ATOM 34190 CB ASP R 248 45.282 37.796 -12.540 1.00177.59 C +ATOM 34191 CG ASP R 248 45.275 38.161 -14.010 1.00158.27 C +ATOM 34192 OD1 ASP R 248 46.367 38.324 -14.601 1.00178.77 O +ATOM 34193 OD2 ASP R 248 44.171 38.324 -14.563 1.00113.09 O +ATOM 34194 N ILE R 249 45.576 36.125 -10.001 1.00199.54 N +ATOM 34195 CA ILE R 249 45.512 36.062 -8.551 1.00175.27 C +ATOM 34196 C ILE R 249 46.708 35.276 -7.997 1.00164.75 C +ATOM 34197 O ILE R 249 47.430 35.752 -7.108 1.00196.03 O +ATOM 34198 CB ILE R 249 44.191 35.407 -8.099 1.00152.37 C +ATOM 34199 CG1 ILE R 249 42.992 36.255 -8.549 1.00145.90 C +ATOM 34200 CG2 ILE R 249 44.168 35.263 -6.591 1.00166.83 C +ATOM 34201 CD1 ILE R 249 41.680 35.501 -8.594 1.00129.17 C +ATOM 34202 N LEU R 250 46.934 34.091 -8.554 1.00137.04 N +ATOM 34203 CA LEU R 250 48.034 33.231 -8.113 1.00152.50 C +ATOM 34204 C LEU R 250 49.416 33.883 -8.237 1.00168.78 C +ATOM 34205 O LEU R 250 50.268 33.701 -7.363 1.00198.70 O +ATOM 34206 CB LEU R 250 48.027 31.916 -8.887 1.00167.37 C +ATOM 34207 CG LEU R 250 46.996 30.890 -8.408 1.00176.07 C +ATOM 34208 CD1 LEU R 250 46.850 29.744 -9.399 1.00206.48 C +ATOM 34209 CD2 LEU R 250 47.387 30.353 -7.046 1.00176.74 C +ATOM 34210 N VAL R 251 49.635 34.635 -9.316 1.00178.95 N +ATOM 34211 CA VAL R 251 50.909 35.341 -9.505 1.00167.78 C +ATOM 34212 C VAL R 251 51.005 36.590 -8.620 1.00176.18 C +ATOM 34213 O VAL R 251 52.105 37.039 -8.285 1.00166.99 O +ATOM 34214 CB VAL R 251 51.149 35.736 -10.977 1.00155.42 C +ATOM 34215 CG1 VAL R 251 51.049 34.512 -11.875 1.00141.95 C +ATOM 34216 CG2 VAL R 251 50.186 36.834 -11.426 1.00158.70 C +ATOM 34217 N LYS R 252 49.854 37.149 -8.248 1.00157.89 N +ATOM 34218 CA LYS R 252 49.811 38.282 -7.325 1.00128.24 C +ATOM 34219 C LYS R 252 50.289 37.858 -5.922 1.00146.83 C +ATOM 34220 O LYS R 252 51.148 38.514 -5.317 1.00140.36 O +ATOM 34221 CB LYS R 252 48.393 38.838 -7.282 1.00114.12 C +ATOM 34222 CG LYS R 252 48.185 40.004 -6.339 1.00123.56 C +ATOM 34223 CD LYS R 252 46.723 40.447 -6.365 1.00131.88 C +ATOM 34224 CE LYS R 252 46.163 40.640 -4.963 1.00129.24 C +ATOM 34225 NZ LYS R 252 44.688 40.824 -4.956 1.00124.29 N +ATOM 34226 N TYR R 253 49.789 36.716 -5.444 1.00160.00 N +ATOM 34227 CA TYR R 253 50.162 36.184 -4.116 1.00134.98 C +ATOM 34228 C TYR R 253 51.533 35.521 -4.139 1.00135.92 C +ATOM 34229 O TYR R 253 52.273 35.575 -3.155 1.00139.75 O +ATOM 34230 CB TYR R 253 49.101 35.203 -3.597 1.00108.39 C +ATOM 34231 CG TYR R 253 47.823 35.914 -3.189 1.00123.77 C +ATOM 34232 CD1 TYR R 253 47.697 36.513 -1.934 1.00107.28 C +ATOM 34233 CD2 TYR R 253 46.789 36.112 -4.108 1.00139.78 C +ATOM 34234 CE1 TYR R 253 46.564 37.244 -1.605 1.00 91.81 C +ATOM 34235 CE2 TYR R 253 45.647 36.841 -3.775 1.00111.50 C +ATOM 34236 CZ TYR R 253 45.536 37.387 -2.512 1.00 88.49 C +ATOM 34237 OH TYR R 253 44.366 38.022 -2.144 1.00 81.10 O +ATOM 34238 N ARG R 254 51.882 34.934 -5.282 1.00146.68 N +ATOM 34239 CA ARG R 254 53.249 34.466 -5.528 1.00132.85 C +ATOM 34240 C ARG R 254 54.245 35.619 -5.404 1.00139.01 C +ATOM 34241 O ARG R 254 55.327 35.462 -4.835 1.00105.77 O +ATOM 34242 CB ARG R 254 53.364 33.852 -6.926 1.00140.32 C +ATOM 34243 CG ARG R 254 54.722 33.232 -7.191 1.00150.18 C +ATOM 34244 CD ARG R 254 54.706 32.279 -8.373 1.00180.06 C +ATOM 34245 NE ARG R 254 53.889 31.089 -8.148 1.00179.60 N +ATOM 34246 CZ ARG R 254 52.720 30.840 -8.732 1.00178.75 C +ATOM 34247 NH1 ARG R 254 52.174 31.712 -9.573 1.00159.26 N +ATOM 34248 NH2 ARG R 254 52.081 29.708 -8.461 1.00169.58 N +ATOM 34249 N HIS R 255 53.852 36.788 -5.922 1.00170.08 N +ATOM 34250 CA HIS R 255 54.690 37.992 -5.870 1.00169.61 C +ATOM 34251 C HIS R 255 54.862 38.533 -4.454 1.00144.27 C +ATOM 34252 O HIS R 255 55.922 39.049 -4.105 1.00115.56 O +ATOM 34253 CB HIS R 255 54.130 39.095 -6.792 1.00173.27 C +ATOM 34254 CG HIS R 255 54.916 39.293 -8.049 1.00173.94 C +ATOM 34255 ND1 HIS R 255 54.848 38.420 -9.112 1.00189.56 N +ATOM 34256 CD2 HIS R 255 55.780 40.270 -8.415 1.00165.01 C +ATOM 34257 CE1 HIS R 255 55.647 38.844 -10.075 1.00201.52 C +ATOM 34258 NE2 HIS R 255 56.225 39.964 -9.677 1.00189.00 N +ATOM 34259 N MET R 256 53.818 38.431 -3.639 1.00142.64 N +ATOM 34260 CA MET R 256 53.911 38.917 -2.264 1.00128.15 C +ATOM 34261 C MET R 256 54.920 38.088 -1.442 1.00128.11 C +ATOM 34262 O MET R 256 55.446 38.586 -0.435 1.00 89.48 O +ATOM 34263 CB MET R 256 52.512 38.968 -1.624 1.00133.96 C +ATOM 34264 CG MET R 256 51.493 39.758 -2.449 1.00134.68 C +ATOM 34265 SD MET R 256 50.031 40.324 -1.568 1.00175.93 S +ATOM 34266 CE MET R 256 50.750 41.566 -0.482 1.00159.43 C +ATOM 34267 N SER R 257 55.173 36.842 -1.881 1.00140.33 N +ATOM 34268 CA SER R 257 56.159 35.934 -1.244 1.00119.40 C +ATOM 34269 C SER R 257 57.591 36.243 -1.640 1.00103.69 C +ATOM 34270 O SER R 257 58.184 37.158 -1.071 1.00120.17 O +ATOM 34271 CB SER R 257 55.860 34.477 -1.594 1.00 98.77 C +ATOM 34272 OG SER R 257 54.459 34.202 -1.512 1.00127.64 O +TER 34273 SER R 257 +MASTER 824 0 0 108 12 0 0 3334255 18 0 378 +END diff --git a/esm/source/examples/inverse_folding/data/5YH2.cif b/esm/source/examples/inverse_folding/data/5YH2.cif new file mode 100644 index 0000000000000000000000000000000000000000..661c0bd208578342eb9762baa50e4a7fb26ec5bc --- /dev/null +++ b/esm/source/examples/inverse_folding/data/5YH2.cif @@ -0,0 +1,18542 @@ +data_5YH2 +# +_entry.id 5YH2 +# +_audit_conform.dict_name mmcif_pdbx.dic +_audit_conform.dict_version 5.291 +_audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic +# +loop_ +_database_2.database_id +_database_2.database_code +PDB 5YH2 +WWPDB D_1300005266 +# +_pdbx_database_status.status_code REL +_pdbx_database_status.status_code_sf REL +_pdbx_database_status.status_code_mr ? +_pdbx_database_status.entry_id 5YH2 +_pdbx_database_status.recvd_initial_deposition_date 2017-09-27 +_pdbx_database_status.SG_entry N +_pdbx_database_status.deposit_site PDBJ +_pdbx_database_status.process_site PDBJ +_pdbx_database_status.status_code_cs ? +_pdbx_database_status.methods_development_category ? +_pdbx_database_status.pdb_format_compatible Y +# +loop_ +_audit_author.name +_audit_author.pdbx_ordinal +_audit_author.identifier_ORCID +'Zhang, H.' 1 ? +'Xiao, J.' 2 ? +# +_citation.abstract ? +_citation.abstract_id_CAS ? +_citation.book_id_ISBN ? +_citation.book_publisher ? +_citation.book_publisher_city ? +_citation.book_title ? +_citation.coordinate_linkage ? +_citation.country UK +_citation.database_id_Medline ? +_citation.details ? +_citation.id primary +_citation.journal_abbrev 'Nat Commun' +_citation.journal_id_ASTM ? +_citation.journal_id_CSD ? +_citation.journal_id_ISSN 2041-1723 +_citation.journal_full ? +_citation.journal_issue ? +_citation.journal_volume 9 +_citation.language ? +_citation.page_first 1218 +_citation.page_last 1218 +_citation.title 'Structure and evolution of the Fam20 kinases' +_citation.year 2018 +_citation.database_id_CSD ? +_citation.pdbx_database_id_DOI 10.1038/s41467-018-03615-z +_citation.pdbx_database_id_PubMed 29572475 +_citation.unpublished_flag ? +# +loop_ +_citation_author.citation_id +_citation_author.name +_citation_author.ordinal +primary 'Zhang, H.' 1 +primary 'Zhu, Q.' 2 +primary 'Cui, J.' 3 +primary 'Wang, Y.' 4 +primary 'Chen, M.J.' 5 +primary 'Guo, X.' 6 +primary 'Tagliabracci, V.S.' 7 +primary 'Dixon, J.E.' 8 +primary 'Xiao, J.' 9 +# +_cell.angle_alpha 90.00 +_cell.angle_alpha_esd ? +_cell.angle_beta 90.00 +_cell.angle_beta_esd ? +_cell.angle_gamma 90.00 +_cell.angle_gamma_esd ? +_cell.entry_id 5YH2 +_cell.details ? +_cell.formula_units_Z ? +_cell.length_a 110.059 +_cell.length_a_esd ? +_cell.length_b 110.059 +_cell.length_b_esd ? +_cell.length_c 461.698 +_cell.length_c_esd ? +_cell.volume ? +_cell.volume_esd ? +_cell.Z_PDB 16 +_cell.reciprocal_angle_alpha ? +_cell.reciprocal_angle_beta ? +_cell.reciprocal_angle_gamma ? +_cell.reciprocal_angle_alpha_esd ? +_cell.reciprocal_angle_beta_esd ? +_cell.reciprocal_angle_gamma_esd ? +_cell.reciprocal_length_a ? +_cell.reciprocal_length_b ? +_cell.reciprocal_length_c ? +_cell.reciprocal_length_a_esd ? +_cell.reciprocal_length_b_esd ? +_cell.reciprocal_length_c_esd ? +_cell.pdbx_unique_axis ? +# +_symmetry.entry_id 5YH2 +_symmetry.cell_setting ? +_symmetry.Int_Tables_number 92 +_symmetry.space_group_name_Hall ? +_symmetry.space_group_name_H-M 'P 41 21 2' +_symmetry.pdbx_full_space_group_name_H-M ? +# +loop_ +_entity.id +_entity.type +_entity.src_method +_entity.pdbx_description +_entity.formula_weight +_entity.pdbx_number_of_molecules +_entity.pdbx_ec +_entity.pdbx_mutation +_entity.pdbx_fragment +_entity.details +1 polymer man 'Pseudokinase FAM20A' 53464.199 2 ? ? 'UNP residues 63-529' ? +2 polymer man 'Family with sequence similarity 20, member Ca' 64505.363 2 ? +'T223A, K421M, A422D, L423M, H425I, Y426F, S427D, L428F, K429L, T430M' ? ? +3 non-polymer man "ADENOSINE-5'-TRIPHOSPHATE" 507.181 2 ? ? ? ATP +# +_entity_name_com.entity_id 2 +_entity_name_com.name DrFam20C1 +# +loop_ +_entity_poly.entity_id +_entity_poly.type +_entity_poly.nstd_linkage +_entity_poly.nstd_monomer +_entity_poly.pdbx_seq_one_letter_code +_entity_poly.pdbx_seq_one_letter_code_can +_entity_poly.pdbx_strand_id +_entity_poly.pdbx_target_identifier +1 'polypeptide(L)' no no +;DPGTIVHNFSRTEPRTEPAGGSHSGSSSKLQALFAHPLYNVPEEPPLLGAEDSLLASQEALRYYRRKVARWNRRHKMYRE +QMNLTSLDPPLQLRLEASWVQFHLGINRHGLYSRSSPVVSKLLQDMRHFPTISADYSQDEKALLGACDCTQIVKPSGVHL +KLVLRFSDFGKAMFKPMRQQRDEETPVDFFYFIDFQRHNAEIAAFHLDRILDFRRVPPTVGRIVNVTKEILEVTKNEILQ +SVFFVSPASNVCFFAKCPYMCKTEYAVCGKPHLLEGSLSAFLPSLNLAPRLSVPNPWIRSYTLAGKEEWEVNPLYCDTVK +QIYPYNNSQRLLNVIDMAIFDFLIGNMDRHHYEMFTKFGDDGFLIHLDNARGFGRHSHDEISILSPLSQCCMIKKKTLLH +LQLLAQADYRLSDVMRESLLEDQLSPVLTEPHLLALDRRLQTILRTVEGCIVAHGQQSVIVDGPVEQ +; +;DPGTIVHNFSRTEPRTEPAGGSHSGSSSKLQALFAHPLYNVPEEPPLLGAEDSLLASQEALRYYRRKVARWNRRHKMYRE +QMNLTSLDPPLQLRLEASWVQFHLGINRHGLYSRSSPVVSKLLQDMRHFPTISADYSQDEKALLGACDCTQIVKPSGVHL +KLVLRFSDFGKAMFKPMRQQRDEETPVDFFYFIDFQRHNAEIAAFHLDRILDFRRVPPTVGRIVNVTKEILEVTKNEILQ +SVFFVSPASNVCFFAKCPYMCKTEYAVCGKPHLLEGSLSAFLPSLNLAPRLSVPNPWIRSYTLAGKEEWEVNPLYCDTVK +QIYPYNNSQRLLNVIDMAIFDFLIGNMDRHHYEMFTKFGDDGFLIHLDNARGFGRHSHDEISILSPLSQCCMIKKKTLLH +LQLLAQADYRLSDVMRESLLEDQLSPVLTEPHLLALDRRLQTILRTVEGCIVAHGQQSVIVDGPVEQ +; +A,B ? +2 'polypeptide(L)' no no +;MILFRKFRVLILTVFLIACTMHIMIDLLPKLEKRAAGSSSSAGGGSGCSCAHTPGEEPRSWGKQRARAADPGWPNKHSLR +LLQDFSNEPNSNLTSQSREKVTERAGSEKQGSGKRGLMREADSRQRRTDVRVSSVLQSLFEHPLYRTVLPDLTEEDTLFN +LNAEIRLYPKAAGQQEWHNEGNVEEEEFSPPGEANSESYPNWLRFHIGINRYELYSRHNPVIAALLRDLLSQKISSVGMK +SGGTQLKLIMSFQNYGQALFKPMKQTREQETPPDFFYFSDFERHNAEIAAFHLDRILDFRRVPPVAGRLVNMTREIRDVT +RDKKLWRTFFVSPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLALAKRKTWRNPWRRSYHKRKKAEWEVDPD +YCDEVKQTPPYDRGTRLLDIMDMTIFDFLMGNMDRHHYETFEKFGNDTFIIHLDNGRGFGKHSHDEMSILVPLTQCCRVK +RSTYLRLQLLAKEEYKLSSLMEESLLQDRLVPVLIKPHLEALDRRLRLVLKVLSDCVEKDGFSAVVENDLDGQPSVHGGR +; +;MILFRKFRVLILTVFLIACTMHIMIDLLPKLEKRAAGSSSSAGGGSGCSCAHTPGEEPRSWGKQRARAADPGWPNKHSLR +LLQDFSNEPNSNLTSQSREKVTERAGSEKQGSGKRGLMREADSRQRRTDVRVSSVLQSLFEHPLYRTVLPDLTEEDTLFN +LNAEIRLYPKAAGQQEWHNEGNVEEEEFSPPGEANSESYPNWLRFHIGINRYELYSRHNPVIAALLRDLLSQKISSVGMK +SGGTQLKLIMSFQNYGQALFKPMKQTREQETPPDFFYFSDFERHNAEIAAFHLDRILDFRRVPPVAGRLVNMTREIRDVT +RDKKLWRTFFVSPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLALAKRKTWRNPWRRSYHKRKKAEWEVDPD +YCDEVKQTPPYDRGTRLLDIMDMTIFDFLMGNMDRHHYETFEKFGNDTFIIHLDNGRGFGKHSHDEMSILVPLTQCCRVK +RSTYLRLQLLAKEEYKLSSLMEESLLQDRLVPVLIKPHLEALDRRLRLVLKVLSDCVEKDGFSAVVENDLDGQPSVHGGR +; +C,D ? +# +loop_ +_entity_poly_seq.entity_id +_entity_poly_seq.num +_entity_poly_seq.mon_id +_entity_poly_seq.hetero +1 1 ASP n +1 2 PRO n +1 3 GLY n +1 4 THR n +1 5 ILE n +1 6 VAL n +1 7 HIS n +1 8 ASN n +1 9 PHE n +1 10 SER n +1 11 ARG n +1 12 THR n +1 13 GLU n +1 14 PRO n +1 15 ARG n +1 16 THR n +1 17 GLU n +1 18 PRO n +1 19 ALA n +1 20 GLY n +1 21 GLY n +1 22 SER n +1 23 HIS n +1 24 SER n +1 25 GLY n +1 26 SER n +1 27 SER n +1 28 SER n +1 29 LYS n +1 30 LEU n +1 31 GLN n +1 32 ALA n +1 33 LEU n +1 34 PHE n +1 35 ALA n +1 36 HIS n +1 37 PRO n +1 38 LEU n +1 39 TYR n +1 40 ASN n +1 41 VAL n +1 42 PRO n +1 43 GLU n +1 44 GLU n +1 45 PRO n +1 46 PRO n +1 47 LEU n +1 48 LEU n +1 49 GLY n +1 50 ALA n +1 51 GLU n +1 52 ASP n +1 53 SER n +1 54 LEU n +1 55 LEU n +1 56 ALA n +1 57 SER n +1 58 GLN n +1 59 GLU n +1 60 ALA n +1 61 LEU n +1 62 ARG n +1 63 TYR n +1 64 TYR n +1 65 ARG n +1 66 ARG n +1 67 LYS n +1 68 VAL n +1 69 ALA n +1 70 ARG n +1 71 TRP n +1 72 ASN n +1 73 ARG n +1 74 ARG n +1 75 HIS n +1 76 LYS n +1 77 MET n +1 78 TYR n +1 79 ARG n +1 80 GLU n +1 81 GLN n +1 82 MET n +1 83 ASN n +1 84 LEU n +1 85 THR n +1 86 SER n +1 87 LEU n +1 88 ASP n +1 89 PRO n +1 90 PRO n +1 91 LEU n +1 92 GLN n +1 93 LEU n +1 94 ARG n +1 95 LEU n +1 96 GLU n +1 97 ALA n +1 98 SER n +1 99 TRP n +1 100 VAL n +1 101 GLN n +1 102 PHE n +1 103 HIS n +1 104 LEU n +1 105 GLY n +1 106 ILE n +1 107 ASN n +1 108 ARG n +1 109 HIS n +1 110 GLY n +1 111 LEU n +1 112 TYR n +1 113 SER n +1 114 ARG n +1 115 SER n +1 116 SER n +1 117 PRO n +1 118 VAL n +1 119 VAL n +1 120 SER n +1 121 LYS n +1 122 LEU n +1 123 LEU n +1 124 GLN n +1 125 ASP n +1 126 MET n +1 127 ARG n +1 128 HIS n +1 129 PHE n +1 130 PRO n +1 131 THR n +1 132 ILE n +1 133 SER n +1 134 ALA n +1 135 ASP n +1 136 TYR n +1 137 SER n +1 138 GLN n +1 139 ASP n +1 140 GLU n +1 141 LYS n +1 142 ALA n +1 143 LEU n +1 144 LEU n +1 145 GLY n +1 146 ALA n +1 147 CYS n +1 148 ASP n +1 149 CYS n +1 150 THR n +1 151 GLN n +1 152 ILE n +1 153 VAL n +1 154 LYS n +1 155 PRO n +1 156 SER n +1 157 GLY n +1 158 VAL n +1 159 HIS n +1 160 LEU n +1 161 LYS n +1 162 LEU n +1 163 VAL n +1 164 LEU n +1 165 ARG n +1 166 PHE n +1 167 SER n +1 168 ASP n +1 169 PHE n +1 170 GLY n +1 171 LYS n +1 172 ALA n +1 173 MET n +1 174 PHE n +1 175 LYS n +1 176 PRO n +1 177 MET n +1 178 ARG n +1 179 GLN n +1 180 GLN n +1 181 ARG n +1 182 ASP n +1 183 GLU n +1 184 GLU n +1 185 THR n +1 186 PRO n +1 187 VAL n +1 188 ASP n +1 189 PHE n +1 190 PHE n +1 191 TYR n +1 192 PHE n +1 193 ILE n +1 194 ASP n +1 195 PHE n +1 196 GLN n +1 197 ARG n +1 198 HIS n +1 199 ASN n +1 200 ALA n +1 201 GLU n +1 202 ILE n +1 203 ALA n +1 204 ALA n +1 205 PHE n +1 206 HIS n +1 207 LEU n +1 208 ASP n +1 209 ARG n +1 210 ILE n +1 211 LEU n +1 212 ASP n +1 213 PHE n +1 214 ARG n +1 215 ARG n +1 216 VAL n +1 217 PRO n +1 218 PRO n +1 219 THR n +1 220 VAL n +1 221 GLY n +1 222 ARG n +1 223 ILE n +1 224 VAL n +1 225 ASN n +1 226 VAL n +1 227 THR n +1 228 LYS n +1 229 GLU n +1 230 ILE n +1 231 LEU n +1 232 GLU n +1 233 VAL n +1 234 THR n +1 235 LYS n +1 236 ASN n +1 237 GLU n +1 238 ILE n +1 239 LEU n +1 240 GLN n +1 241 SER n +1 242 VAL n +1 243 PHE n +1 244 PHE n +1 245 VAL n +1 246 SER n +1 247 PRO n +1 248 ALA n +1 249 SER n +1 250 ASN n +1 251 VAL n +1 252 CYS n +1 253 PHE n +1 254 PHE n +1 255 ALA n +1 256 LYS n +1 257 CYS n +1 258 PRO n +1 259 TYR n +1 260 MET n +1 261 CYS n +1 262 LYS n +1 263 THR n +1 264 GLU n +1 265 TYR n +1 266 ALA n +1 267 VAL n +1 268 CYS n +1 269 GLY n +1 270 LYS n +1 271 PRO n +1 272 HIS n +1 273 LEU n +1 274 LEU n +1 275 GLU n +1 276 GLY n +1 277 SER n +1 278 LEU n +1 279 SER n +1 280 ALA n +1 281 PHE n +1 282 LEU n +1 283 PRO n +1 284 SER n +1 285 LEU n +1 286 ASN n +1 287 LEU n +1 288 ALA n +1 289 PRO n +1 290 ARG n +1 291 LEU n +1 292 SER n +1 293 VAL n +1 294 PRO n +1 295 ASN n +1 296 PRO n +1 297 TRP n +1 298 ILE n +1 299 ARG n +1 300 SER n +1 301 TYR n +1 302 THR n +1 303 LEU n +1 304 ALA n +1 305 GLY n +1 306 LYS n +1 307 GLU n +1 308 GLU n +1 309 TRP n +1 310 GLU n +1 311 VAL n +1 312 ASN n +1 313 PRO n +1 314 LEU n +1 315 TYR n +1 316 CYS n +1 317 ASP n +1 318 THR n +1 319 VAL n +1 320 LYS n +1 321 GLN n +1 322 ILE n +1 323 TYR n +1 324 PRO n +1 325 TYR n +1 326 ASN n +1 327 ASN n +1 328 SER n +1 329 GLN n +1 330 ARG n +1 331 LEU n +1 332 LEU n +1 333 ASN n +1 334 VAL n +1 335 ILE n +1 336 ASP n +1 337 MET n +1 338 ALA n +1 339 ILE n +1 340 PHE n +1 341 ASP n +1 342 PHE n +1 343 LEU n +1 344 ILE n +1 345 GLY n +1 346 ASN n +1 347 MET n +1 348 ASP n +1 349 ARG n +1 350 HIS n +1 351 HIS n +1 352 TYR n +1 353 GLU n +1 354 MET n +1 355 PHE n +1 356 THR n +1 357 LYS n +1 358 PHE n +1 359 GLY n +1 360 ASP n +1 361 ASP n +1 362 GLY n +1 363 PHE n +1 364 LEU n +1 365 ILE n +1 366 HIS n +1 367 LEU n +1 368 ASP n +1 369 ASN n +1 370 ALA n +1 371 ARG n +1 372 GLY n +1 373 PHE n +1 374 GLY n +1 375 ARG n +1 376 HIS n +1 377 SER n +1 378 HIS n +1 379 ASP n +1 380 GLU n +1 381 ILE n +1 382 SER n +1 383 ILE n +1 384 LEU n +1 385 SER n +1 386 PRO n +1 387 LEU n +1 388 SER n +1 389 GLN n +1 390 CYS n +1 391 CYS n +1 392 MET n +1 393 ILE n +1 394 LYS n +1 395 LYS n +1 396 LYS n +1 397 THR n +1 398 LEU n +1 399 LEU n +1 400 HIS n +1 401 LEU n +1 402 GLN n +1 403 LEU n +1 404 LEU n +1 405 ALA n +1 406 GLN n +1 407 ALA n +1 408 ASP n +1 409 TYR n +1 410 ARG n +1 411 LEU n +1 412 SER n +1 413 ASP n +1 414 VAL n +1 415 MET n +1 416 ARG n +1 417 GLU n +1 418 SER n +1 419 LEU n +1 420 LEU n +1 421 GLU n +1 422 ASP n +1 423 GLN n +1 424 LEU n +1 425 SER n +1 426 PRO n +1 427 VAL n +1 428 LEU n +1 429 THR n +1 430 GLU n +1 431 PRO n +1 432 HIS n +1 433 LEU n +1 434 LEU n +1 435 ALA n +1 436 LEU n +1 437 ASP n +1 438 ARG n +1 439 ARG n +1 440 LEU n +1 441 GLN n +1 442 THR n +1 443 ILE n +1 444 LEU n +1 445 ARG n +1 446 THR n +1 447 VAL n +1 448 GLU n +1 449 GLY n +1 450 CYS n +1 451 ILE n +1 452 VAL n +1 453 ALA n +1 454 HIS n +1 455 GLY n +1 456 GLN n +1 457 GLN n +1 458 SER n +1 459 VAL n +1 460 ILE n +1 461 VAL n +1 462 ASP n +1 463 GLY n +1 464 PRO n +1 465 VAL n +1 466 GLU n +1 467 GLN n +2 1 MET n +2 2 ILE n +2 3 LEU n +2 4 PHE n +2 5 ARG n +2 6 LYS n +2 7 PHE n +2 8 ARG n +2 9 VAL n +2 10 LEU n +2 11 ILE n +2 12 LEU n +2 13 THR n +2 14 VAL n +2 15 PHE n +2 16 LEU n +2 17 ILE n +2 18 ALA n +2 19 CYS n +2 20 THR n +2 21 MET n +2 22 HIS n +2 23 ILE n +2 24 MET n +2 25 ILE n +2 26 ASP n +2 27 LEU n +2 28 LEU n +2 29 PRO n +2 30 LYS n +2 31 LEU n +2 32 GLU n +2 33 LYS n +2 34 ARG n +2 35 ALA n +2 36 ALA n +2 37 GLY n +2 38 SER n +2 39 SER n +2 40 SER n +2 41 SER n +2 42 ALA n +2 43 GLY n +2 44 GLY n +2 45 GLY n +2 46 SER n +2 47 GLY n +2 48 CYS n +2 49 SER n +2 50 CYS n +2 51 ALA n +2 52 HIS n +2 53 THR n +2 54 PRO n +2 55 GLY n +2 56 GLU n +2 57 GLU n +2 58 PRO n +2 59 ARG n +2 60 SER n +2 61 TRP n +2 62 GLY n +2 63 LYS n +2 64 GLN n +2 65 ARG n +2 66 ALA n +2 67 ARG n +2 68 ALA n +2 69 ALA n +2 70 ASP n +2 71 PRO n +2 72 GLY n +2 73 TRP n +2 74 PRO n +2 75 ASN n +2 76 LYS n +2 77 HIS n +2 78 SER n +2 79 LEU n +2 80 ARG n +2 81 LEU n +2 82 LEU n +2 83 GLN n +2 84 ASP n +2 85 PHE n +2 86 SER n +2 87 ASN n +2 88 GLU n +2 89 PRO n +2 90 ASN n +2 91 SER n +2 92 ASN n +2 93 LEU n +2 94 THR n +2 95 SER n +2 96 GLN n +2 97 SER n +2 98 ARG n +2 99 GLU n +2 100 LYS n +2 101 VAL n +2 102 THR n +2 103 GLU n +2 104 ARG n +2 105 ALA n +2 106 GLY n +2 107 SER n +2 108 GLU n +2 109 LYS n +2 110 GLN n +2 111 GLY n +2 112 SER n +2 113 GLY n +2 114 LYS n +2 115 ARG n +2 116 GLY n +2 117 LEU n +2 118 MET n +2 119 ARG n +2 120 GLU n +2 121 ALA n +2 122 ASP n +2 123 SER n +2 124 ARG n +2 125 GLN n +2 126 ARG n +2 127 ARG n +2 128 THR n +2 129 ASP n +2 130 VAL n +2 131 ARG n +2 132 VAL n +2 133 SER n +2 134 SER n +2 135 VAL n +2 136 LEU n +2 137 GLN n +2 138 SER n +2 139 LEU n +2 140 PHE n +2 141 GLU n +2 142 HIS n +2 143 PRO n +2 144 LEU n +2 145 TYR n +2 146 ARG n +2 147 THR n +2 148 VAL n +2 149 LEU n +2 150 PRO n +2 151 ASP n +2 152 LEU n +2 153 THR n +2 154 GLU n +2 155 GLU n +2 156 ASP n +2 157 THR n +2 158 LEU n +2 159 PHE n +2 160 ASN n +2 161 LEU n +2 162 ASN n +2 163 ALA n +2 164 GLU n +2 165 ILE n +2 166 ARG n +2 167 LEU n +2 168 TYR n +2 169 PRO n +2 170 LYS n +2 171 ALA n +2 172 ALA n +2 173 GLY n +2 174 GLN n +2 175 GLN n +2 176 GLU n +2 177 TRP n +2 178 HIS n +2 179 ASN n +2 180 GLU n +2 181 GLY n +2 182 ASN n +2 183 VAL n +2 184 GLU n +2 185 GLU n +2 186 GLU n +2 187 GLU n +2 188 PHE n +2 189 SER n +2 190 PRO n +2 191 PRO n +2 192 GLY n +2 193 GLU n +2 194 ALA n +2 195 ASN n +2 196 SER n +2 197 GLU n +2 198 SER n +2 199 TYR n +2 200 PRO n +2 201 ASN n +2 202 TRP n +2 203 LEU n +2 204 ARG n +2 205 PHE n +2 206 HIS n +2 207 ILE n +2 208 GLY n +2 209 ILE n +2 210 ASN n +2 211 ARG n +2 212 TYR n +2 213 GLU n +2 214 LEU n +2 215 TYR n +2 216 SER n +2 217 ARG n +2 218 HIS n +2 219 ASN n +2 220 PRO n +2 221 VAL n +2 222 ILE n +2 223 ALA n +2 224 ALA n +2 225 LEU n +2 226 LEU n +2 227 ARG n +2 228 ASP n +2 229 LEU n +2 230 LEU n +2 231 SER n +2 232 GLN n +2 233 LYS n +2 234 ILE n +2 235 SER n +2 236 SER n +2 237 VAL n +2 238 GLY n +2 239 MET n +2 240 LYS n +2 241 SER n +2 242 GLY n +2 243 GLY n +2 244 THR n +2 245 GLN n +2 246 LEU n +2 247 LYS n +2 248 LEU n +2 249 ILE n +2 250 MET n +2 251 SER n +2 252 PHE n +2 253 GLN n +2 254 ASN n +2 255 TYR n +2 256 GLY n +2 257 GLN n +2 258 ALA n +2 259 LEU n +2 260 PHE n +2 261 LYS n +2 262 PRO n +2 263 MET n +2 264 LYS n +2 265 GLN n +2 266 THR n +2 267 ARG n +2 268 GLU n +2 269 GLN n +2 270 GLU n +2 271 THR n +2 272 PRO n +2 273 PRO n +2 274 ASP n +2 275 PHE n +2 276 PHE n +2 277 TYR n +2 278 PHE n +2 279 SER n +2 280 ASP n +2 281 PHE n +2 282 GLU n +2 283 ARG n +2 284 HIS n +2 285 ASN n +2 286 ALA n +2 287 GLU n +2 288 ILE n +2 289 ALA n +2 290 ALA n +2 291 PHE n +2 292 HIS n +2 293 LEU n +2 294 ASP n +2 295 ARG n +2 296 ILE n +2 297 LEU n +2 298 ASP n +2 299 PHE n +2 300 ARG n +2 301 ARG n +2 302 VAL n +2 303 PRO n +2 304 PRO n +2 305 VAL n +2 306 ALA n +2 307 GLY n +2 308 ARG n +2 309 LEU n +2 310 VAL n +2 311 ASN n +2 312 MET n +2 313 THR n +2 314 ARG n +2 315 GLU n +2 316 ILE n +2 317 ARG n +2 318 ASP n +2 319 VAL n +2 320 THR n +2 321 ARG n +2 322 ASP n +2 323 LYS n +2 324 LYS n +2 325 LEU n +2 326 TRP n +2 327 ARG n +2 328 THR n +2 329 PHE n +2 330 PHE n +2 331 VAL n +2 332 SER n +2 333 PRO n +2 334 ALA n +2 335 ASN n +2 336 ASN n +2 337 ILE n +2 338 CYS n +2 339 PHE n +2 340 TYR n +2 341 GLY n +2 342 GLU n +2 343 CYS n +2 344 SER n +2 345 TYR n +2 346 TYR n +2 347 CYS n +2 348 SER n +2 349 THR n +2 350 GLU n +2 351 HIS n +2 352 ALA n +2 353 LEU n +2 354 CYS n +2 355 GLY n +2 356 LYS n +2 357 PRO n +2 358 ASP n +2 359 GLN n +2 360 ILE n +2 361 GLU n +2 362 GLY n +2 363 SER n +2 364 LEU n +2 365 ALA n +2 366 ALA n +2 367 PHE n +2 368 LEU n +2 369 PRO n +2 370 ASP n +2 371 LEU n +2 372 ALA n +2 373 LEU n +2 374 ALA n +2 375 LYS n +2 376 ARG n +2 377 LYS n +2 378 THR n +2 379 TRP n +2 380 ARG n +2 381 ASN n +2 382 PRO n +2 383 TRP n +2 384 ARG n +2 385 ARG n +2 386 SER n +2 387 TYR n +2 388 HIS n +2 389 LYS n +2 390 ARG n +2 391 LYS n +2 392 LYS n +2 393 ALA n +2 394 GLU n +2 395 TRP n +2 396 GLU n +2 397 VAL n +2 398 ASP n +2 399 PRO n +2 400 ASP n +2 401 TYR n +2 402 CYS n +2 403 ASP n +2 404 GLU n +2 405 VAL n +2 406 LYS n +2 407 GLN n +2 408 THR n +2 409 PRO n +2 410 PRO n +2 411 TYR n +2 412 ASP n +2 413 ARG n +2 414 GLY n +2 415 THR n +2 416 ARG n +2 417 LEU n +2 418 LEU n +2 419 ASP n +2 420 ILE n +2 421 MET n +2 422 ASP n +2 423 MET n +2 424 THR n +2 425 ILE n +2 426 PHE n +2 427 ASP n +2 428 PHE n +2 429 LEU n +2 430 MET n +2 431 GLY n +2 432 ASN n +2 433 MET n +2 434 ASP n +2 435 ARG n +2 436 HIS n +2 437 HIS n +2 438 TYR n +2 439 GLU n +2 440 THR n +2 441 PHE n +2 442 GLU n +2 443 LYS n +2 444 PHE n +2 445 GLY n +2 446 ASN n +2 447 ASP n +2 448 THR n +2 449 PHE n +2 450 ILE n +2 451 ILE n +2 452 HIS n +2 453 LEU n +2 454 ASP n +2 455 ASN n +2 456 GLY n +2 457 ARG n +2 458 GLY n +2 459 PHE n +2 460 GLY n +2 461 LYS n +2 462 HIS n +2 463 SER n +2 464 HIS n +2 465 ASP n +2 466 GLU n +2 467 MET n +2 468 SER n +2 469 ILE n +2 470 LEU n +2 471 VAL n +2 472 PRO n +2 473 LEU n +2 474 THR n +2 475 GLN n +2 476 CYS n +2 477 CYS n +2 478 ARG n +2 479 VAL n +2 480 LYS n +2 481 ARG n +2 482 SER n +2 483 THR n +2 484 TYR n +2 485 LEU n +2 486 ARG n +2 487 LEU n +2 488 GLN n +2 489 LEU n +2 490 LEU n +2 491 ALA n +2 492 LYS n +2 493 GLU n +2 494 GLU n +2 495 TYR n +2 496 LYS n +2 497 LEU n +2 498 SER n +2 499 SER n +2 500 LEU n +2 501 MET n +2 502 GLU n +2 503 GLU n +2 504 SER n +2 505 LEU n +2 506 LEU n +2 507 GLN n +2 508 ASP n +2 509 ARG n +2 510 LEU n +2 511 VAL n +2 512 PRO n +2 513 VAL n +2 514 LEU n +2 515 ILE n +2 516 LYS n +2 517 PRO n +2 518 HIS n +2 519 LEU n +2 520 GLU n +2 521 ALA n +2 522 LEU n +2 523 ASP n +2 524 ARG n +2 525 ARG n +2 526 LEU n +2 527 ARG n +2 528 LEU n +2 529 VAL n +2 530 LEU n +2 531 LYS n +2 532 VAL n +2 533 LEU n +2 534 SER n +2 535 ASP n +2 536 CYS n +2 537 VAL n +2 538 GLU n +2 539 LYS n +2 540 ASP n +2 541 GLY n +2 542 PHE n +2 543 SER n +2 544 ALA n +2 545 VAL n +2 546 VAL n +2 547 GLU n +2 548 ASN n +2 549 ASP n +2 550 LEU n +2 551 ASP n +2 552 GLY n +2 553 GLN n +2 554 PRO n +2 555 SER n +2 556 VAL n +2 557 HIS n +2 558 GLY n +2 559 GLY n +2 560 ARG n +# +loop_ +_entity_src_gen.entity_id +_entity_src_gen.pdbx_src_id +_entity_src_gen.pdbx_alt_source_flag +_entity_src_gen.pdbx_seq_type +_entity_src_gen.pdbx_beg_seq_num +_entity_src_gen.pdbx_end_seq_num +_entity_src_gen.gene_src_common_name +_entity_src_gen.gene_src_genus +_entity_src_gen.pdbx_gene_src_gene +_entity_src_gen.gene_src_species +_entity_src_gen.gene_src_strain +_entity_src_gen.gene_src_tissue +_entity_src_gen.gene_src_tissue_fraction +_entity_src_gen.gene_src_details +_entity_src_gen.pdbx_gene_src_fragment +_entity_src_gen.pdbx_gene_src_scientific_name +_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id +_entity_src_gen.pdbx_gene_src_variant +_entity_src_gen.pdbx_gene_src_cell_line +_entity_src_gen.pdbx_gene_src_atcc +_entity_src_gen.pdbx_gene_src_organ +_entity_src_gen.pdbx_gene_src_organelle +_entity_src_gen.pdbx_gene_src_cell +_entity_src_gen.pdbx_gene_src_cellular_location +_entity_src_gen.host_org_common_name +_entity_src_gen.pdbx_host_org_scientific_name +_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id +_entity_src_gen.host_org_genus +_entity_src_gen.pdbx_host_org_gene +_entity_src_gen.pdbx_host_org_organ +_entity_src_gen.host_org_species +_entity_src_gen.pdbx_host_org_tissue +_entity_src_gen.pdbx_host_org_tissue_fraction +_entity_src_gen.pdbx_host_org_strain +_entity_src_gen.pdbx_host_org_variant +_entity_src_gen.pdbx_host_org_cell_line +_entity_src_gen.pdbx_host_org_atcc +_entity_src_gen.pdbx_host_org_culture_collection +_entity_src_gen.pdbx_host_org_cell +_entity_src_gen.pdbx_host_org_organelle +_entity_src_gen.pdbx_host_org_cellular_location +_entity_src_gen.pdbx_host_org_vector_type +_entity_src_gen.pdbx_host_org_vector +_entity_src_gen.host_org_details +_entity_src_gen.expression_system_id +_entity_src_gen.plasmid_name +_entity_src_gen.plasmid_details +_entity_src_gen.pdbx_description +1 1 sample 'Biological sequence' 1 467 Human ? 'FAM20A, UNQ9388/PRO34279' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? +'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? +2 1 sample 'Biological sequence' 1 560 Zebrafish ? fam20ca ? ? ? ? ? ? 'Danio rerio' 7955 ? ? ? ? ? ? ? ? +'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? +# +loop_ +_struct_ref.id +_struct_ref.db_name +_struct_ref.db_code +_struct_ref.pdbx_db_accession +_struct_ref.pdbx_db_isoform +_struct_ref.entity_id +_struct_ref.pdbx_seq_one_letter_code +_struct_ref.pdbx_align_begin +1 UNP FA20A_HUMAN Q96MK3 ? 1 +;DPGTIVHNFSRTEPRTEPAGGSHSGSSSKLQALFAHPLYNVPEEPPLLGAEDSLLASQEALRYYRRKVARWNRRHKMYRE +QMNLTSLDPPLQLRLEASWVQFHLGINRHGLYSRSSPVVSKLLQDMRHFPTISADYSQDEKALLGACDCTQIVKPSGVHL +KLVLRFSDFGKAMFKPMRQQRDEETPVDFFYFIDFQRHNAEIAAFHLDRILDFRRVPPTVGRIVNVTKEILEVTKNEILQ +SVFFVSPASNVCFFAKCPYMCKTEYAVCGNPHLLEGSLSAFLPSLNLAPRLSVPNPWIRSYTLAGKEEWEVNPLYCDTVK +QIYPYNNSQRLLNVIDMAIFDFLIGNMDRHHYEMFTKFGDDGFLIHLDNARGFGRHSHDEISILSPLSQCCMIKKKTLLH +LQLLAQADYRLSDVMRESLLEDQLSPVLTEPHLLALDRRLQTILRTVEGCIVAHGQQSVIVDGPVEQ +; +63 +2 UNP E7FBB8_DANRE E7FBB8 ? 2 +;MILFRKFRVLILTVFLIACTMHIMIDLLPKLEKRAAGSSSSAGGGSGCSCAHTPGEEPRSWGKQRARAADPGWPNKHSLR +LLQDFSNEPNSNLTSQSREKVTERAGSEKQGSGKRGLMREADSRQRRTDVRVSSVLQSLFEHPLYRTVLPDLTEEDTLFN +LNAEIRLYPKAAGQQEWHNEGNVEEEEFSPPGEANSESYPNWLRFHIGINRYELYSRHNPVITALLRDLLSQKISSVGMK +SGGTQLKLIMSFQNYGQALFKPMKQTREQETPPDFFYFSDFERHNAEIAAFHLDRILDFRRVPPVAGRLVNMTREIRDVT +RDKKLWRTFFVSPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLALAKRKTWRNPWRRSYHKRKKAEWEVDPD +YCDEVKQTPPYDRGTRLLDIKALTHYSLKTGNMDRHHYETFEKFGNDTFIIHLDNGRGFGKHSHDEMSILVPLTQCCRVK +RSTYLRLQLLAKEEYKLSSLMEESLLQDRLVPVLIKPHLEALDRRLRLVLKVLSDCVEKDGFSAVVENDLDGQPSVHGGR + +; +1 +# +loop_ +_struct_ref_seq.align_id +_struct_ref_seq.ref_id +_struct_ref_seq.pdbx_PDB_id_code +_struct_ref_seq.pdbx_strand_id +_struct_ref_seq.seq_align_beg +_struct_ref_seq.pdbx_seq_align_beg_ins_code +_struct_ref_seq.seq_align_end +_struct_ref_seq.pdbx_seq_align_end_ins_code +_struct_ref_seq.pdbx_db_accession +_struct_ref_seq.db_align_beg +_struct_ref_seq.pdbx_db_align_beg_ins_code +_struct_ref_seq.db_align_end +_struct_ref_seq.pdbx_db_align_end_ins_code +_struct_ref_seq.pdbx_auth_seq_align_beg +_struct_ref_seq.pdbx_auth_seq_align_end +1 1 5YH2 A 1 ? 467 ? Q96MK3 63 ? 529 ? 63 529 +2 2 5YH2 C 1 ? 560 ? E7FBB8 1 ? 560 ? 1 560 +3 1 5YH2 B 1 ? 467 ? Q96MK3 63 ? 529 ? 63 529 +4 2 5YH2 D 1 ? 560 ? E7FBB8 1 ? 560 ? 1 560 +# +loop_ +_struct_ref_seq_dif.align_id +_struct_ref_seq_dif.pdbx_pdb_id_code +_struct_ref_seq_dif.mon_id +_struct_ref_seq_dif.pdbx_pdb_strand_id +_struct_ref_seq_dif.seq_num +_struct_ref_seq_dif.pdbx_pdb_ins_code +_struct_ref_seq_dif.pdbx_seq_db_name +_struct_ref_seq_dif.pdbx_seq_db_accession_code +_struct_ref_seq_dif.db_mon_id +_struct_ref_seq_dif.pdbx_seq_db_seq_num +_struct_ref_seq_dif.details +_struct_ref_seq_dif.pdbx_auth_seq_num +_struct_ref_seq_dif.pdbx_ordinal +1 5YH2 LYS A 270 ? UNP Q96MK3 ASN 332 variant 332 1 +2 5YH2 ALA C 223 ? UNP E7FBB8 THR 223 'engineered mutation' 223 2 +2 5YH2 MET C 421 ? UNP E7FBB8 LYS 421 'engineered mutation' 421 3 +2 5YH2 ASP C 422 ? UNP E7FBB8 ALA 422 'engineered mutation' 422 4 +2 5YH2 MET C 423 ? UNP E7FBB8 LEU 423 'engineered mutation' 423 5 +2 5YH2 ILE C 425 ? UNP E7FBB8 HIS 425 'engineered mutation' 425 6 +2 5YH2 PHE C 426 ? UNP E7FBB8 TYR 426 'engineered mutation' 426 7 +2 5YH2 ASP C 427 ? UNP E7FBB8 SER 427 'engineered mutation' 427 8 +2 5YH2 PHE C 428 ? UNP E7FBB8 LEU 428 'engineered mutation' 428 9 +2 5YH2 LEU C 429 ? UNP E7FBB8 LYS 429 'engineered mutation' 429 10 +2 5YH2 MET C 430 ? UNP E7FBB8 THR 430 'engineered mutation' 430 11 +3 5YH2 LYS B 270 ? UNP Q96MK3 ASN 332 variant 332 12 +4 5YH2 ALA D 223 ? UNP E7FBB8 THR 223 'engineered mutation' 223 13 +4 5YH2 MET D 421 ? UNP E7FBB8 LYS 421 'engineered mutation' 421 14 +4 5YH2 ASP D 422 ? UNP E7FBB8 ALA 422 'engineered mutation' 422 15 +4 5YH2 MET D 423 ? UNP E7FBB8 LEU 423 'engineered mutation' 423 16 +4 5YH2 ILE D 425 ? UNP E7FBB8 HIS 425 'engineered mutation' 425 17 +4 5YH2 PHE D 426 ? UNP E7FBB8 TYR 426 'engineered mutation' 426 18 +4 5YH2 ASP D 427 ? UNP E7FBB8 SER 427 'engineered mutation' 427 19 +4 5YH2 PHE D 428 ? UNP E7FBB8 LEU 428 'engineered mutation' 428 20 +4 5YH2 LEU D 429 ? UNP E7FBB8 LYS 429 'engineered mutation' 429 21 +4 5YH2 MET D 430 ? UNP E7FBB8 THR 430 'engineered mutation' 430 22 +# +loop_ +_chem_comp.id +_chem_comp.type +_chem_comp.mon_nstd_flag +_chem_comp.name +_chem_comp.pdbx_synonyms +_chem_comp.formula +_chem_comp.formula_weight +ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 +ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 +ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 +ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 +ATP non-polymer . "ADENOSINE-5'-TRIPHOSPHATE" ? 'C10 H16 N5 O13 P3' 507.181 +CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 +GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 +GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 +GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 +HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 +ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 +LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 +LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 +MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 +PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 +PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 +SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 +THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 +TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 +TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 +VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 +# +_exptl.absorpt_coefficient_mu ? +_exptl.absorpt_correction_T_max ? +_exptl.absorpt_correction_T_min ? +_exptl.absorpt_correction_type ? +_exptl.absorpt_process_details ? +_exptl.entry_id 5YH2 +_exptl.crystals_number 1 +_exptl.details ? +_exptl.method 'X-RAY DIFFRACTION' +_exptl.method_details ? +# +_exptl_crystal.colour ? +_exptl_crystal.density_diffrn ? +_exptl_crystal.density_Matthews 2.96 +_exptl_crystal.density_method ? +_exptl_crystal.density_percent_sol 58.49 +_exptl_crystal.description ? +_exptl_crystal.F_000 ? +_exptl_crystal.id 1 +_exptl_crystal.preparation ? +_exptl_crystal.size_max ? +_exptl_crystal.size_mid ? +_exptl_crystal.size_min ? +_exptl_crystal.size_rad ? +_exptl_crystal.colour_lustre ? +_exptl_crystal.colour_modifier ? +_exptl_crystal.colour_primary ? +_exptl_crystal.density_meas ? +_exptl_crystal.density_meas_esd ? +_exptl_crystal.density_meas_gt ? +_exptl_crystal.density_meas_lt ? +_exptl_crystal.density_meas_temp ? +_exptl_crystal.density_meas_temp_esd ? +_exptl_crystal.density_meas_temp_gt ? +_exptl_crystal.density_meas_temp_lt ? +_exptl_crystal.pdbx_crystal_image_url ? +_exptl_crystal.pdbx_crystal_image_format ? +_exptl_crystal.pdbx_mosaicity ? +_exptl_crystal.pdbx_mosaicity_esd ? +# +_exptl_crystal_grow.apparatus ? +_exptl_crystal_grow.atmosphere ? +_exptl_crystal_grow.crystal_id 1 +_exptl_crystal_grow.details ? +_exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' +_exptl_crystal_grow.method_ref ? +_exptl_crystal_grow.pH 5.0 +_exptl_crystal_grow.pressure ? +_exptl_crystal_grow.pressure_esd ? +_exptl_crystal_grow.seeding ? +_exptl_crystal_grow.seeding_ref ? +_exptl_crystal_grow.temp 290 +_exptl_crystal_grow.temp_details ? +_exptl_crystal_grow.temp_esd ? +_exptl_crystal_grow.time ? +_exptl_crystal_grow.pdbx_details +'11% v/v 2-Propanol, 0.1 M Sodium citrate tribasic dihydrate pH 5.0, 8% w/v Polyethylene glycol 10,000' +_exptl_crystal_grow.pdbx_pH_range ? +# +_diffrn.ambient_environment ? +_diffrn.ambient_temp 100 +_diffrn.ambient_temp_details ? +_diffrn.ambient_temp_esd ? +_diffrn.crystal_id 1 +_diffrn.crystal_support ? +_diffrn.crystal_treatment ? +_diffrn.details ? +_diffrn.id 1 +_diffrn.ambient_pressure ? +_diffrn.ambient_pressure_esd ? +_diffrn.ambient_pressure_gt ? +_diffrn.ambient_pressure_lt ? +_diffrn.ambient_temp_gt ? +_diffrn.ambient_temp_lt ? +# +_diffrn_detector.details ? +_diffrn_detector.detector PIXEL +_diffrn_detector.diffrn_id 1 +_diffrn_detector.type 'DECTRIS PILATUS3 6M' +_diffrn_detector.area_resol_mean ? +_diffrn_detector.dtime ? +_diffrn_detector.pdbx_frames_total ? +_diffrn_detector.pdbx_collection_time_total ? +_diffrn_detector.pdbx_collection_date 2016-10-02 +# +_diffrn_radiation.collimation ? +_diffrn_radiation.diffrn_id 1 +_diffrn_radiation.filter_edge ? +_diffrn_radiation.inhomogeneity ? +_diffrn_radiation.monochromator ? +_diffrn_radiation.polarisn_norm ? +_diffrn_radiation.polarisn_ratio ? +_diffrn_radiation.probe ? +_diffrn_radiation.type ? +_diffrn_radiation.xray_symbol ? +_diffrn_radiation.wavelength_id 1 +_diffrn_radiation.pdbx_monochromatic_or_laue_m_l M +_diffrn_radiation.pdbx_wavelength_list ? +_diffrn_radiation.pdbx_wavelength ? +_diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' +_diffrn_radiation.pdbx_analyzer ? +_diffrn_radiation.pdbx_scattering_type x-ray +# +_diffrn_radiation_wavelength.id 1 +_diffrn_radiation_wavelength.wavelength 0.977 +_diffrn_radiation_wavelength.wt 1.0 +# +_diffrn_source.current ? +_diffrn_source.details ? +_diffrn_source.diffrn_id 1 +_diffrn_source.power ? +_diffrn_source.size ? +_diffrn_source.source SYNCHROTRON +_diffrn_source.target ? +_diffrn_source.type 'SSRF BEAMLINE BL18U1' +_diffrn_source.voltage ? +_diffrn_source.take-off_angle ? +_diffrn_source.pdbx_wavelength_list 0.977 +_diffrn_source.pdbx_wavelength ? +_diffrn_source.pdbx_synchrotron_beamline BL18U1 +_diffrn_source.pdbx_synchrotron_site SSRF +# +_reflns.B_iso_Wilson_estimate ? +_reflns.entry_id 5YH2 +_reflns.data_reduction_details ? +_reflns.data_reduction_method ? +_reflns.d_resolution_high 3.55 +_reflns.d_resolution_low 50 +_reflns.details ? +_reflns.limit_h_max ? +_reflns.limit_h_min ? +_reflns.limit_k_max ? +_reflns.limit_k_min ? +_reflns.limit_l_max ? +_reflns.limit_l_min ? +_reflns.number_all ? +_reflns.number_obs 35615 +_reflns.observed_criterion ? +_reflns.observed_criterion_F_max ? +_reflns.observed_criterion_F_min ? +_reflns.observed_criterion_I_max ? +_reflns.observed_criterion_I_min ? +_reflns.observed_criterion_sigma_F ? +_reflns.observed_criterion_sigma_I ? +_reflns.percent_possible_obs 100 +_reflns.R_free_details ? +_reflns.Rmerge_F_all ? +_reflns.Rmerge_F_obs ? +_reflns.Friedel_coverage ? +_reflns.number_gt ? +_reflns.threshold_expression ? +_reflns.pdbx_redundancy 11.4 +_reflns.pdbx_Rmerge_I_obs ? +_reflns.pdbx_Rmerge_I_all ? +_reflns.pdbx_Rsym_value ? +_reflns.pdbx_netI_over_av_sigmaI ? +_reflns.pdbx_netI_over_sigmaI 11 +_reflns.pdbx_res_netI_over_av_sigmaI_2 ? +_reflns.pdbx_res_netI_over_sigmaI_2 ? +_reflns.pdbx_chi_squared ? +_reflns.pdbx_scaling_rejects ? +_reflns.pdbx_d_res_high_opt ? +_reflns.pdbx_d_res_low_opt ? +_reflns.pdbx_d_res_opt_method ? +_reflns.phase_calculation_details ? +_reflns.pdbx_Rrim_I_all ? +_reflns.pdbx_Rpim_I_all ? +_reflns.pdbx_d_opt ? +_reflns.pdbx_number_measured_all ? +_reflns.pdbx_diffrn_id 1 +_reflns.pdbx_ordinal 1 +_reflns.pdbx_CC_half ? +_reflns.pdbx_R_split ? +# +_reflns_shell.d_res_high . +_reflns_shell.d_res_low ? +_reflns_shell.meanI_over_sigI_all ? +_reflns_shell.meanI_over_sigI_obs ? +_reflns_shell.number_measured_all ? +_reflns_shell.number_measured_obs ? +_reflns_shell.number_possible ? +_reflns_shell.number_unique_all ? +_reflns_shell.number_unique_obs ? +_reflns_shell.percent_possible_all ? +_reflns_shell.percent_possible_obs ? +_reflns_shell.Rmerge_F_all ? +_reflns_shell.Rmerge_F_obs ? +_reflns_shell.Rmerge_I_all ? +_reflns_shell.Rmerge_I_obs ? +_reflns_shell.meanI_over_sigI_gt ? +_reflns_shell.meanI_over_uI_all ? +_reflns_shell.meanI_over_uI_gt ? +_reflns_shell.number_measured_gt ? +_reflns_shell.number_unique_gt ? +_reflns_shell.percent_possible_gt ? +_reflns_shell.Rmerge_F_gt ? +_reflns_shell.Rmerge_I_gt ? +_reflns_shell.pdbx_redundancy ? +_reflns_shell.pdbx_Rsym_value ? +_reflns_shell.pdbx_chi_squared ? +_reflns_shell.pdbx_netI_over_sigmaI_all ? +_reflns_shell.pdbx_netI_over_sigmaI_obs ? +_reflns_shell.pdbx_Rrim_I_all ? +_reflns_shell.pdbx_Rpim_I_all ? +_reflns_shell.pdbx_rejects ? +_reflns_shell.pdbx_ordinal 1 +_reflns_shell.pdbx_diffrn_id 1 +_reflns_shell.pdbx_CC_half ? +_reflns_shell.pdbx_R_split ? +# +_refine.aniso_B[1][1] ? +_refine.aniso_B[1][2] ? +_refine.aniso_B[1][3] ? +_refine.aniso_B[2][2] ? +_refine.aniso_B[2][3] ? +_refine.aniso_B[3][3] ? +_refine.B_iso_max ? +_refine.B_iso_mean ? +_refine.B_iso_min ? +_refine.correlation_coeff_Fo_to_Fc ? +_refine.correlation_coeff_Fo_to_Fc_free ? +_refine.details ? +_refine.diff_density_max ? +_refine.diff_density_max_esd ? +_refine.diff_density_min ? +_refine.diff_density_min_esd ? +_refine.diff_density_rms ? +_refine.diff_density_rms_esd ? +_refine.entry_id 5YH2 +_refine.pdbx_refine_id 'X-RAY DIFFRACTION' +_refine.ls_abs_structure_details ? +_refine.ls_abs_structure_Flack ? +_refine.ls_abs_structure_Flack_esd ? +_refine.ls_abs_structure_Rogers ? +_refine.ls_abs_structure_Rogers_esd ? +_refine.ls_d_res_high 3.550 +_refine.ls_d_res_low 48.943 +_refine.ls_extinction_coef ? +_refine.ls_extinction_coef_esd ? +_refine.ls_extinction_expression ? +_refine.ls_extinction_method ? +_refine.ls_goodness_of_fit_all ? +_refine.ls_goodness_of_fit_all_esd ? +_refine.ls_goodness_of_fit_obs ? +_refine.ls_goodness_of_fit_obs_esd ? +_refine.ls_hydrogen_treatment ? +_refine.ls_matrix_type ? +_refine.ls_number_constraints ? +_refine.ls_number_parameters ? +_refine.ls_number_reflns_all ? +_refine.ls_number_reflns_obs 31136 +_refine.ls_number_reflns_R_free 1556 +_refine.ls_number_reflns_R_work ? +_refine.ls_number_restraints ? +_refine.ls_percent_reflns_obs 87.70 +_refine.ls_percent_reflns_R_free 5.00 +_refine.ls_R_factor_all ? +_refine.ls_R_factor_obs 0.2480 +_refine.ls_R_factor_R_free 0.2984 +_refine.ls_R_factor_R_free_error ? +_refine.ls_R_factor_R_free_error_details ? +_refine.ls_R_factor_R_work 0.2454 +_refine.ls_R_Fsqd_factor_obs ? +_refine.ls_R_I_factor_obs ? +_refine.ls_redundancy_reflns_all ? +_refine.ls_redundancy_reflns_obs ? +_refine.ls_restrained_S_all ? +_refine.ls_restrained_S_obs ? +_refine.ls_shift_over_esd_max ? +_refine.ls_shift_over_esd_mean ? +_refine.ls_structure_factor_coef ? +_refine.ls_weighting_details ? +_refine.ls_weighting_scheme ? +_refine.ls_wR_factor_all ? +_refine.ls_wR_factor_obs ? +_refine.ls_wR_factor_R_free ? +_refine.ls_wR_factor_R_work ? +_refine.occupancy_max ? +_refine.occupancy_min ? +_refine.solvent_model_details ? +_refine.solvent_model_param_bsol ? +_refine.solvent_model_param_ksol ? +_refine.ls_R_factor_gt ? +_refine.ls_goodness_of_fit_gt ? +_refine.ls_goodness_of_fit_ref ? +_refine.ls_shift_over_su_max ? +_refine.ls_shift_over_su_max_lt ? +_refine.ls_shift_over_su_mean ? +_refine.ls_shift_over_su_mean_lt ? +_refine.pdbx_ls_sigma_I ? +_refine.pdbx_ls_sigma_F 1.34 +_refine.pdbx_ls_sigma_Fsqd ? +_refine.pdbx_data_cutoff_high_absF ? +_refine.pdbx_data_cutoff_high_rms_absF ? +_refine.pdbx_data_cutoff_low_absF ? +_refine.pdbx_isotropic_thermal_model ? +_refine.pdbx_ls_cross_valid_method 'FREE R-VALUE' +_refine.pdbx_method_to_determine_struct ? +_refine.pdbx_starting_model ? +_refine.pdbx_stereochemistry_target_values ? +_refine.pdbx_R_Free_selection_details ? +_refine.pdbx_stereochem_target_val_spec_case ? +_refine.pdbx_overall_ESU_R ? +_refine.pdbx_overall_ESU_R_Free ? +_refine.pdbx_solvent_vdw_probe_radii 1.11 +_refine.pdbx_solvent_ion_probe_radii ? +_refine.pdbx_solvent_shrinkage_radii 0.90 +_refine.pdbx_real_space_R ? +_refine.pdbx_density_correlation ? +_refine.pdbx_pd_number_of_powder_patterns ? +_refine.pdbx_pd_number_of_points ? +_refine.pdbx_pd_meas_number_of_points ? +_refine.pdbx_pd_proc_ls_prof_R_factor ? +_refine.pdbx_pd_proc_ls_prof_wR_factor ? +_refine.pdbx_pd_Marquardt_correlation_coeff ? +_refine.pdbx_pd_Fsqrd_R_factor ? +_refine.pdbx_pd_ls_matrix_band_width ? +_refine.pdbx_overall_phase_error 28.88 +_refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? +_refine.pdbx_overall_SU_R_free_Blow_DPI ? +_refine.pdbx_overall_SU_R_Blow_DPI ? +_refine.pdbx_TLS_residual_ADP_flag ? +_refine.pdbx_diffrn_id 1 +_refine.overall_SU_B ? +_refine.overall_SU_ML 0.50 +_refine.overall_SU_R_Cruickshank_DPI ? +_refine.overall_SU_R_free ? +_refine.overall_FOM_free_R_set ? +_refine.overall_FOM_work_R_set ? +_refine.pdbx_average_fsc_overall ? +_refine.pdbx_average_fsc_work ? +_refine.pdbx_average_fsc_free ? +# +_refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' +_refine_hist.cycle_id LAST +_refine_hist.pdbx_number_atoms_protein 13431 +_refine_hist.pdbx_number_atoms_nucleic_acid 0 +_refine_hist.pdbx_number_atoms_ligand 62 +_refine_hist.number_atoms_solvent 0 +_refine_hist.number_atoms_total 13493 +_refine_hist.d_res_high 3.550 +_refine_hist.d_res_low 48.943 +# +loop_ +_refine_ls_restr.pdbx_refine_id +_refine_ls_restr.criterion +_refine_ls_restr.dev_ideal +_refine_ls_restr.dev_ideal_target +_refine_ls_restr.number +_refine_ls_restr.rejects +_refine_ls_restr.type +_refine_ls_restr.weight +_refine_ls_restr.pdbx_restraint_function +'X-RAY DIFFRACTION' ? 0.005 ? 13846 ? f_bond_d ? ? +'X-RAY DIFFRACTION' ? 0.739 ? 18758 ? f_angle_d ? ? +'X-RAY DIFFRACTION' ? 15.217 ? 8431 ? f_dihedral_angle_d ? ? +'X-RAY DIFFRACTION' ? 0.044 ? 2028 ? f_chiral_restr ? ? +'X-RAY DIFFRACTION' ? 0.006 ? 2410 ? f_plane_restr ? ? +# +loop_ +_refine_ls_shell.pdbx_refine_id +_refine_ls_shell.d_res_high +_refine_ls_shell.d_res_low +_refine_ls_shell.number_reflns_all +_refine_ls_shell.number_reflns_obs +_refine_ls_shell.number_reflns_R_free +_refine_ls_shell.number_reflns_R_work +_refine_ls_shell.percent_reflns_obs +_refine_ls_shell.percent_reflns_R_free +_refine_ls_shell.R_factor_all +_refine_ls_shell.R_factor_obs +_refine_ls_shell.R_factor_R_free +_refine_ls_shell.R_factor_R_free_error +_refine_ls_shell.R_factor_R_work +_refine_ls_shell.redundancy_reflns_all +_refine_ls_shell.redundancy_reflns_obs +_refine_ls_shell.wR_factor_all +_refine_ls_shell.wR_factor_obs +_refine_ls_shell.wR_factor_R_free +_refine_ls_shell.wR_factor_R_work +_refine_ls_shell.pdbx_total_number_of_bins_used +_refine_ls_shell.pdbx_phase_error +_refine_ls_shell.pdbx_fsc_work +_refine_ls_shell.pdbx_fsc_free +'X-RAY DIFFRACTION' 3.5504 3.6650 . . 62 1169 39.00 . . . 0.3218 . 0.2907 . . . . . . . . . . +'X-RAY DIFFRACTION' 3.6650 3.7959 . . 78 1493 50.00 . . . 0.3970 . 0.2939 . . . . . . . . . . +'X-RAY DIFFRACTION' 3.7959 3.9478 . . 120 2288 77.00 . . . 0.3518 . 0.2929 . . . . . . . . . . +'X-RAY DIFFRACTION' 3.9478 4.1274 . . 157 2973 99.00 . . . 0.3451 . 0.2931 . . . . . . . . . . +'X-RAY DIFFRACTION' 4.1274 4.3449 . . 158 3000 100.00 . . . 0.3580 . 0.2688 . . . . . . . . . . +'X-RAY DIFFRACTION' 4.3449 4.6169 . . 160 3037 100.00 . . . 0.2814 . 0.2402 . . . . . . . . . . +'X-RAY DIFFRACTION' 4.6169 4.9731 . . 160 3051 100.00 . . . 0.2652 . 0.2193 . . . . . . . . . . +'X-RAY DIFFRACTION' 4.9731 5.4729 . . 161 3062 100.00 . . . 0.2819 . 0.2260 . . . . . . . . . . +'X-RAY DIFFRACTION' 5.4729 6.2635 . . 163 3076 100.00 . . . 0.2841 . 0.2375 . . . . . . . . . . +'X-RAY DIFFRACTION' 6.2635 7.8860 . . 166 3161 100.00 . . . 0.2823 . 0.2337 . . . . . . . . . . +'X-RAY DIFFRACTION' 7.8860 48.9472 . . 171 3270 98.00 . . . 0.2582 . 0.2169 . . . . . . . . . . +# +_struct.entry_id 5YH2 +_struct.title 'The structure of DrFam20C1 and hFam20A complex' +_struct.pdbx_descriptor 'Pseudokinase FAM20A, DrFam20C1' +_struct.pdbx_model_details ? +_struct.pdbx_formula_weight ? +_struct.pdbx_formula_weight_method ? +_struct.pdbx_model_type_details ? +_struct.pdbx_CASP_flag N +# +_struct_keywords.entry_id 5YH2 +_struct_keywords.text 'complex, kinase, TRANSFERASE' +_struct_keywords.pdbx_keywords TRANSFERASE +# +loop_ +_struct_asym.id +_struct_asym.pdbx_blank_PDB_chainid_flag +_struct_asym.pdbx_modified +_struct_asym.entity_id +_struct_asym.details +A N N 1 ? +B N N 2 ? +C N N 1 ? +D N N 2 ? +E N N 3 ? +F N N 3 ? +# +loop_ +_struct_conf.conf_type_id +_struct_conf.id +_struct_conf.pdbx_PDB_helix_id +_struct_conf.beg_label_comp_id +_struct_conf.beg_label_asym_id +_struct_conf.beg_label_seq_id +_struct_conf.pdbx_beg_PDB_ins_code +_struct_conf.end_label_comp_id +_struct_conf.end_label_asym_id +_struct_conf.end_label_seq_id +_struct_conf.pdbx_end_PDB_ins_code +_struct_conf.beg_auth_comp_id +_struct_conf.beg_auth_asym_id +_struct_conf.beg_auth_seq_id +_struct_conf.end_auth_comp_id +_struct_conf.end_auth_asym_id +_struct_conf.end_auth_seq_id +_struct_conf.pdbx_PDB_helix_class +_struct_conf.details +_struct_conf.pdbx_PDB_helix_length +HELX_P HELX_P1 AA1 SER A 28 ? ALA A 35 ? SER A 90 ALA A 97 1 ? 8 +HELX_P HELX_P2 AA2 HIS A 36 ? ASN A 40 ? HIS A 98 ASN A 102 5 ? 5 +HELX_P HELX_P3 AA3 ALA A 56 ? MET A 77 ? ALA A 118 MET A 139 1 ? 22 +HELX_P HELX_P4 AA4 ALA A 97 ? GLY A 105 ? ALA A 159 GLY A 167 1 ? 9 +HELX_P HELX_P5 AA5 SER A 116 ? PHE A 129 ? SER A 178 PHE A 191 1 ? 14 +HELX_P HELX_P6 AA6 PHE A 190 ? ASP A 194 ? PHE A 252 ASP A 256 5 ? 5 +HELX_P HELX_P7 AA7 ARG A 197 ? LEU A 211 ? ARG A 259 LEU A 273 1 ? 15 +HELX_P HELX_P8 AA8 ILE A 230 ? THR A 234 ? ILE A 292 THR A 296 5 ? 5 +HELX_P HELX_P9 AA9 ASN A 236 ? VAL A 242 ? ASN A 298 VAL A 304 1 ? 7 +HELX_P HELX_P10 AB1 ALA A 255 ? CYS A 261 ? ALA A 317 CYS A 323 1 ? 7 +HELX_P HELX_P11 AB2 LEU A 314 ? LYS A 320 ? LEU A 376 LYS A 382 1 ? 7 +HELX_P HELX_P12 AB3 PRO A 324 ? SER A 328 ? PRO A 386 SER A 390 5 ? 5 +HELX_P HELX_P13 AB4 GLN A 329 ? GLY A 345 ? GLN A 391 GLY A 407 1 ? 17 +HELX_P HELX_P14 AB5 LYS A 357 ? GLY A 359 ? LYS A 419 GLY A 421 5 ? 3 +HELX_P HELX_P15 AB6 GLU A 380 ? ILE A 383 ? GLU A 442 ILE A 445 5 ? 4 +HELX_P HELX_P16 AB7 LEU A 384 ? CYS A 391 ? LEU A 446 CYS A 453 1 ? 8 +HELX_P HELX_P17 AB8 LYS A 395 ? LEU A 404 ? LYS A 457 LEU A 466 1 ? 10 +HELX_P HELX_P18 AB9 ALA A 405 ? TYR A 409 ? ALA A 467 TYR A 471 5 ? 5 +HELX_P HELX_P19 AC1 ARG A 410 ? LEU A 419 ? ARG A 472 LEU A 481 1 ? 10 +HELX_P HELX_P20 AC2 LEU A 420 ? ASP A 422 ? LEU A 482 ASP A 484 5 ? 3 +HELX_P HELX_P21 AC3 THR A 429 ? VAL A 459 ? THR A 491 VAL A 521 1 ? 31 +HELX_P HELX_P22 AC4 VAL B 135 ? HIS B 142 ? VAL C 135 HIS C 142 1 ? 8 +HELX_P HELX_P23 AC5 ASN B 160 ? GLU B 164 ? ASN C 160 GLU C 164 5 ? 5 +HELX_P HELX_P24 AC6 PRO B 200 ? GLY B 208 ? PRO C 200 GLY C 208 1 ? 9 +HELX_P HELX_P25 AC7 ASN B 219 ? GLN B 232 ? ASN C 219 GLN C 232 1 ? 14 +HELX_P HELX_P26 AC8 PHE B 276 ? ASP B 280 ? PHE C 276 ASP C 280 5 ? 5 +HELX_P HELX_P27 AC9 ARG B 283 ? LEU B 297 ? ARG C 283 LEU C 297 1 ? 15 +HELX_P HELX_P28 AD1 ILE B 316 ? THR B 320 ? ILE C 316 THR C 320 5 ? 5 +HELX_P HELX_P29 AD2 ASP B 322 ? ARG B 327 ? ASP C 322 ARG C 327 1 ? 6 +HELX_P HELX_P30 AD3 SER B 348 ? ALA B 352 ? SER C 348 ALA C 352 5 ? 5 +HELX_P HELX_P31 AD4 ALA B 393 ? VAL B 397 ? ALA C 393 VAL C 397 5 ? 5 +HELX_P HELX_P32 AD5 ASP B 400 ? LYS B 406 ? ASP C 400 LYS C 406 1 ? 7 +HELX_P HELX_P33 AD6 LEU B 417 ? GLY B 431 ? LEU C 417 GLY C 431 1 ? 15 +HELX_P HELX_P34 AD7 GLU B 466 ? ILE B 469 ? GLU C 466 ILE C 469 5 ? 4 +HELX_P HELX_P35 AD8 LEU B 470 ? CYS B 477 ? LEU C 470 CYS C 477 1 ? 8 +HELX_P HELX_P36 AD9 ARG B 481 ? LEU B 490 ? ARG C 481 LEU C 490 1 ? 10 +HELX_P HELX_P37 AE1 LEU B 497 ? LEU B 506 ? LEU C 497 LEU C 506 1 ? 10 +HELX_P HELX_P38 AE2 ILE B 515 ? GLY B 541 ? ILE C 515 GLY C 541 1 ? 27 +HELX_P HELX_P39 AE3 SER C 28 ? ALA C 35 ? SER B 90 ALA B 97 1 ? 8 +HELX_P HELX_P40 AE4 HIS C 36 ? VAL C 41 ? HIS B 98 VAL B 103 5 ? 6 +HELX_P HELX_P41 AE5 ALA C 56 ? TYR C 78 ? ALA B 118 TYR B 140 1 ? 23 +HELX_P HELX_P42 AE6 ALA C 97 ? GLY C 105 ? ALA B 159 GLY B 167 1 ? 9 +HELX_P HELX_P43 AE7 SER C 116 ? PHE C 129 ? SER B 178 PHE B 191 1 ? 14 +HELX_P HELX_P44 AE8 PHE C 190 ? ASP C 194 ? PHE B 252 ASP B 256 5 ? 5 +HELX_P HELX_P45 AE9 ARG C 197 ? LEU C 211 ? ARG B 259 LEU B 273 1 ? 15 +HELX_P HELX_P46 AF1 ILE C 230 ? THR C 234 ? ILE B 292 THR B 296 5 ? 5 +HELX_P HELX_P47 AF2 ASN C 236 ? VAL C 242 ? ASN B 298 VAL B 304 1 ? 7 +HELX_P HELX_P48 AF3 ALA C 255 ? CYS C 261 ? ALA B 317 CYS B 323 1 ? 7 +HELX_P HELX_P49 AF4 GLU C 307 ? ASN C 312 ? GLU B 369 ASN B 374 1 ? 6 +HELX_P HELX_P50 AF5 LEU C 314 ? LYS C 320 ? LEU B 376 LYS B 382 1 ? 7 +HELX_P HELX_P51 AF6 GLN C 329 ? GLY C 345 ? GLN B 391 GLY B 407 1 ? 17 +HELX_P HELX_P52 AF7 LYS C 357 ? GLY C 359 ? LYS B 419 GLY B 421 5 ? 3 +HELX_P HELX_P53 AF8 GLU C 380 ? ILE C 383 ? GLU B 442 ILE B 445 5 ? 4 +HELX_P HELX_P54 AF9 LEU C 384 ? CYS C 391 ? LEU B 446 CYS B 453 1 ? 8 +HELX_P HELX_P55 AG1 LYS C 395 ? LEU C 404 ? LYS B 457 LEU B 466 1 ? 10 +HELX_P HELX_P56 AG2 ALA C 405 ? TYR C 409 ? ALA B 467 TYR B 471 5 ? 5 +HELX_P HELX_P57 AG3 ARG C 410 ? LEU C 419 ? ARG B 472 LEU B 481 1 ? 10 +HELX_P HELX_P58 AG4 LEU C 420 ? ASP C 422 ? LEU B 482 ASP B 484 5 ? 3 +HELX_P HELX_P59 AG5 THR C 429 ? VAL C 459 ? THR B 491 VAL B 521 1 ? 31 +HELX_P HELX_P60 AG6 VAL D 135 ? HIS D 142 ? VAL D 135 HIS D 142 1 ? 8 +HELX_P HELX_P61 AG7 ASN D 160 ? GLU D 164 ? ASN D 160 GLU D 164 5 ? 5 +HELX_P HELX_P62 AG8 PRO D 200 ? GLY D 208 ? PRO D 200 GLY D 208 1 ? 9 +HELX_P HELX_P63 AG9 ASN D 219 ? GLN D 232 ? ASN D 219 GLN D 232 1 ? 14 +HELX_P HELX_P64 AH1 ARG D 283 ? LEU D 297 ? ARG D 283 LEU D 297 1 ? 15 +HELX_P HELX_P65 AH2 ILE D 316 ? THR D 320 ? ILE D 316 THR D 320 5 ? 5 +HELX_P HELX_P66 AH3 ASP D 322 ? ARG D 327 ? ASP D 322 ARG D 327 1 ? 6 +HELX_P HELX_P67 AH4 SER D 348 ? ALA D 352 ? SER D 348 ALA D 352 5 ? 5 +HELX_P HELX_P68 AH5 ALA D 393 ? VAL D 397 ? ALA D 393 VAL D 397 5 ? 5 +HELX_P HELX_P69 AH6 ASP D 400 ? LYS D 406 ? ASP D 400 LYS D 406 1 ? 7 +HELX_P HELX_P70 AH7 LEU D 417 ? GLY D 431 ? LEU D 417 GLY D 431 1 ? 15 +HELX_P HELX_P71 AH8 GLU D 466 ? ILE D 469 ? GLU D 466 ILE D 469 5 ? 4 +HELX_P HELX_P72 AH9 LEU D 470 ? CYS D 477 ? LEU D 470 CYS D 477 1 ? 8 +HELX_P HELX_P73 AI1 ARG D 481 ? LEU D 490 ? ARG D 481 LEU D 490 1 ? 10 +HELX_P HELX_P74 AI2 LEU D 497 ? LEU D 505 ? LEU D 497 LEU D 505 1 ? 9 +HELX_P HELX_P75 AI3 ILE D 515 ? GLY D 541 ? ILE D 515 GLY D 541 1 ? 27 +# +_struct_conf_type.id HELX_P +_struct_conf_type.criteria ? +_struct_conf_type.reference ? +# +loop_ +_struct_conn.id +_struct_conn.conn_type_id +_struct_conn.pdbx_leaving_atom_flag +_struct_conn.pdbx_PDB_id +_struct_conn.ptnr1_label_asym_id +_struct_conn.ptnr1_label_comp_id +_struct_conn.ptnr1_label_seq_id +_struct_conn.ptnr1_label_atom_id +_struct_conn.pdbx_ptnr1_label_alt_id +_struct_conn.pdbx_ptnr1_PDB_ins_code +_struct_conn.pdbx_ptnr1_standard_comp_id +_struct_conn.ptnr1_symmetry +_struct_conn.ptnr2_label_asym_id +_struct_conn.ptnr2_label_comp_id +_struct_conn.ptnr2_label_seq_id +_struct_conn.ptnr2_label_atom_id +_struct_conn.pdbx_ptnr2_label_alt_id +_struct_conn.pdbx_ptnr2_PDB_ins_code +_struct_conn.ptnr1_auth_asym_id +_struct_conn.ptnr1_auth_comp_id +_struct_conn.ptnr1_auth_seq_id +_struct_conn.ptnr2_auth_asym_id +_struct_conn.ptnr2_auth_comp_id +_struct_conn.ptnr2_auth_seq_id +_struct_conn.ptnr2_symmetry +_struct_conn.pdbx_ptnr3_label_atom_id +_struct_conn.pdbx_ptnr3_label_seq_id +_struct_conn.pdbx_ptnr3_label_comp_id +_struct_conn.pdbx_ptnr3_label_asym_id +_struct_conn.pdbx_ptnr3_label_alt_id +_struct_conn.pdbx_ptnr3_PDB_ins_code +_struct_conn.details +_struct_conn.pdbx_dist_value +_struct_conn.pdbx_value_order +disulf1 disulf ? ? A CYS 147 SG ? ? ? 1_555 A CYS 257 SG ? ? A CYS 209 A CYS 319 1_555 ? ? ? ? ? ? ? 2.035 ? +disulf2 disulf ? ? A CYS 149 SG ? ? ? 1_555 A CYS 261 SG ? ? A CYS 211 A CYS 323 1_555 ? ? ? ? ? ? ? 2.035 ? +disulf3 disulf ? ? A CYS 252 SG ? ? ? 1_555 A CYS 268 SG ? ? A CYS 314 A CYS 330 1_555 ? ? ? ? ? ? ? 2.030 ? +disulf4 disulf ? ? A CYS 316 SG ? ? ? 1_555 A CYS 390 SG ? ? A CYS 378 A CYS 452 1_555 ? ? ? ? ? ? ? 2.032 ? +disulf5 disulf ? ? A CYS 391 SG ? ? ? 1_555 A CYS 450 SG ? ? A CYS 453 A CYS 512 1_555 ? ? ? ? ? ? ? 2.036 ? +disulf6 disulf ? ? B CYS 338 SG ? ? ? 1_555 B CYS 354 SG ? ? C CYS 338 C CYS 354 1_555 ? ? ? ? ? ? ? 2.032 ? +disulf7 disulf ? ? B CYS 343 SG ? ? ? 1_555 B CYS 347 SG ? ? C CYS 343 C CYS 347 1_555 ? ? ? ? ? ? ? 2.033 ? +disulf8 disulf ? ? B CYS 402 SG ? ? ? 1_555 B CYS 476 SG ? ? C CYS 402 C CYS 476 1_555 ? ? ? ? ? ? ? 2.034 ? +disulf9 disulf ? ? B CYS 477 SG ? ? ? 1_555 B CYS 536 SG ? ? C CYS 477 C CYS 536 1_555 ? ? ? ? ? ? ? 2.022 ? +disulf10 disulf ? ? C CYS 147 SG ? ? ? 1_555 C CYS 257 SG ? ? B CYS 209 B CYS 319 1_555 ? ? ? ? ? ? ? 2.035 ? +disulf11 disulf ? ? C CYS 149 SG ? ? ? 1_555 C CYS 261 SG ? ? B CYS 211 B CYS 323 1_555 ? ? ? ? ? ? ? 2.038 ? +disulf12 disulf ? ? C CYS 252 SG ? ? ? 1_555 C CYS 268 SG ? ? B CYS 314 B CYS 330 1_555 ? ? ? ? ? ? ? 2.031 ? +disulf13 disulf ? ? C CYS 316 SG ? ? ? 1_555 C CYS 390 SG ? ? B CYS 378 B CYS 452 1_555 ? ? ? ? ? ? ? 2.035 ? +disulf14 disulf ? ? C CYS 391 SG ? ? ? 1_555 C CYS 450 SG ? ? B CYS 453 B CYS 512 1_555 ? ? ? ? ? ? ? 2.031 ? +disulf15 disulf ? ? D CYS 338 SG ? ? ? 1_555 D CYS 354 SG ? ? D CYS 338 D CYS 354 1_555 ? ? ? ? ? ? ? 2.033 ? +disulf16 disulf ? ? D CYS 343 SG ? ? ? 1_555 D CYS 347 SG ? ? D CYS 343 D CYS 347 1_555 ? ? ? ? ? ? ? 2.032 ? +disulf17 disulf ? ? D CYS 402 SG ? ? ? 1_555 D CYS 476 SG ? ? D CYS 402 D CYS 476 1_555 ? ? ? ? ? ? ? 2.032 ? +disulf18 disulf ? ? D CYS 477 SG ? ? ? 1_555 D CYS 536 SG ? ? D CYS 477 D CYS 536 1_555 ? ? ? ? ? ? ? 2.018 ? +# +_struct_conn_type.id disulf +_struct_conn_type.criteria ? +_struct_conn_type.reference ? +# +loop_ +_struct_mon_prot_cis.pdbx_id +_struct_mon_prot_cis.label_comp_id +_struct_mon_prot_cis.label_seq_id +_struct_mon_prot_cis.label_asym_id +_struct_mon_prot_cis.label_alt_id +_struct_mon_prot_cis.pdbx_PDB_ins_code +_struct_mon_prot_cis.auth_comp_id +_struct_mon_prot_cis.auth_seq_id +_struct_mon_prot_cis.auth_asym_id +_struct_mon_prot_cis.pdbx_label_comp_id_2 +_struct_mon_prot_cis.pdbx_label_seq_id_2 +_struct_mon_prot_cis.pdbx_label_asym_id_2 +_struct_mon_prot_cis.pdbx_PDB_ins_code_2 +_struct_mon_prot_cis.pdbx_auth_comp_id_2 +_struct_mon_prot_cis.pdbx_auth_seq_id_2 +_struct_mon_prot_cis.pdbx_auth_asym_id_2 +_struct_mon_prot_cis.pdbx_PDB_model_num +_struct_mon_prot_cis.pdbx_omega_angle +1 GLU 44 A . ? GLU 106 A PRO 45 A ? PRO 107 A 1 -3.63 +2 GLY 145 A . ? GLY 207 A ALA 146 A ? ALA 208 A 1 -5.09 +3 LYS 270 A . ? LYS 332 A PRO 271 A ? PRO 333 A 1 -7.68 +4 TYR 323 A . ? TYR 385 A PRO 324 A ? PRO 386 A 1 1.19 +5 SER 425 A . ? SER 487 A PRO 426 A ? PRO 488 A 1 1.76 +6 LYS 356 B . ? LYS 356 C PRO 357 B ? PRO 357 C 1 -4.96 +7 GLY 414 B . ? GLY 414 C THR 415 B ? THR 415 C 1 -3.41 +8 VAL 511 B . ? VAL 511 C PRO 512 B ? PRO 512 C 1 -1.77 +9 GLU 44 C . ? GLU 106 B PRO 45 C ? PRO 107 B 1 -4.25 +10 GLY 145 C . ? GLY 207 B ALA 146 C ? ALA 208 B 1 -4.68 +11 LYS 270 C . ? LYS 332 B PRO 271 C ? PRO 333 B 1 -7.18 +12 TYR 323 C . ? TYR 385 B PRO 324 C ? PRO 386 B 1 1.49 +13 SER 425 C . ? SER 487 B PRO 426 C ? PRO 488 B 1 0.98 +14 LYS 356 D . ? LYS 356 D PRO 357 D ? PRO 357 D 1 -4.39 +15 GLY 414 D . ? GLY 414 D THR 415 D ? THR 415 D 1 -4.05 +16 VAL 511 D . ? VAL 511 D PRO 512 D ? PRO 512 D 1 -1.90 +# +loop_ +_struct_sheet.id +_struct_sheet.type +_struct_sheet.number_strands +_struct_sheet.details +AA1 ? 5 ? +AA2 ? 3 ? +AA3 ? 3 ? +AA4 ? 2 ? +AA5 ? 5 ? +AA6 ? 3 ? +AA7 ? 2 ? +AA8 ? 2 ? +AA9 ? 5 ? +AB1 ? 3 ? +AB2 ? 3 ? +AB3 ? 2 ? +AB4 ? 5 ? +AB5 ? 3 ? +AB6 ? 2 ? +AB7 ? 2 ? +# +loop_ +_struct_sheet_order.sheet_id +_struct_sheet_order.range_id_1 +_struct_sheet_order.range_id_2 +_struct_sheet_order.offset +_struct_sheet_order.sense +AA1 1 2 ? anti-parallel +AA1 2 3 ? anti-parallel +AA1 3 4 ? anti-parallel +AA1 4 5 ? anti-parallel +AA2 1 2 ? anti-parallel +AA2 2 3 ? anti-parallel +AA3 1 2 ? anti-parallel +AA3 2 3 ? anti-parallel +AA4 1 2 ? parallel +AA5 1 2 ? anti-parallel +AA5 2 3 ? anti-parallel +AA5 3 4 ? anti-parallel +AA5 4 5 ? anti-parallel +AA6 1 2 ? anti-parallel +AA6 2 3 ? anti-parallel +AA7 1 2 ? anti-parallel +AA8 1 2 ? parallel +AA9 1 2 ? anti-parallel +AA9 2 3 ? anti-parallel +AA9 3 4 ? anti-parallel +AA9 4 5 ? anti-parallel +AB1 1 2 ? anti-parallel +AB1 2 3 ? anti-parallel +AB2 1 2 ? anti-parallel +AB2 2 3 ? anti-parallel +AB3 1 2 ? parallel +AB4 1 2 ? anti-parallel +AB4 2 3 ? anti-parallel +AB4 3 4 ? anti-parallel +AB4 4 5 ? anti-parallel +AB5 1 2 ? anti-parallel +AB5 2 3 ? anti-parallel +AB6 1 2 ? anti-parallel +AB7 1 2 ? parallel +# +loop_ +_struct_sheet_range.sheet_id +_struct_sheet_range.id +_struct_sheet_range.beg_label_comp_id +_struct_sheet_range.beg_label_asym_id +_struct_sheet_range.beg_label_seq_id +_struct_sheet_range.pdbx_beg_PDB_ins_code +_struct_sheet_range.end_label_comp_id +_struct_sheet_range.end_label_asym_id +_struct_sheet_range.end_label_seq_id +_struct_sheet_range.pdbx_end_PDB_ins_code +_struct_sheet_range.beg_auth_comp_id +_struct_sheet_range.beg_auth_asym_id +_struct_sheet_range.beg_auth_seq_id +_struct_sheet_range.end_auth_comp_id +_struct_sheet_range.end_auth_asym_id +_struct_sheet_range.end_auth_seq_id +AA1 1 THR A 131 ? ASP A 135 ? THR A 193 ASP A 197 +AA1 2 LEU A 162 ? PHE A 166 ? LEU A 224 PHE A 228 +AA1 3 LYS A 171 ? PRO A 176 ? LYS A 233 PRO A 238 +AA1 4 LEU A 273 ? ALA A 280 ? LEU A 335 ALA A 342 +AA1 5 THR A 219 ? ASN A 225 ? THR A 281 ASN A 287 +AA2 1 PHE A 244 ? VAL A 245 ? PHE A 306 VAL A 307 +AA2 2 VAL A 251 ? PHE A 253 ? VAL A 313 PHE A 315 +AA2 3 VAL A 267 ? CYS A 268 ? VAL A 329 CYS A 330 +AA3 1 ARG A 290 ? PRO A 294 ? ARG A 352 PRO A 356 +AA3 2 HIS A 351 ? PHE A 355 ? HIS A 413 PHE A 417 +AA3 3 LEU A 364 ? ILE A 365 ? LEU A 426 ILE A 427 +AA4 1 ILE A 393 ? LYS A 394 ? ILE A 455 LYS A 456 +AA4 2 ILE A 460 ? VAL A 461 ? ILE A 522 VAL A 523 +AA5 1 ILE B 234 ? MET B 239 ? ILE C 234 MET C 239 +AA5 2 LEU B 248 ? PHE B 252 ? LEU C 248 PHE C 252 +AA5 3 GLN B 257 ? PRO B 262 ? GLN C 257 PRO C 262 +AA5 4 GLY B 362 ? ALA B 366 ? GLY C 362 ALA C 366 +AA5 5 VAL B 305 ? ARG B 308 ? VAL C 305 ARG C 308 +AA6 1 PHE B 330 ? VAL B 331 ? PHE C 330 VAL C 331 +AA6 2 ILE B 337 ? PHE B 339 ? ILE C 337 PHE C 339 +AA6 3 LEU B 353 ? CYS B 354 ? LEU C 353 CYS C 354 +AA7 1 THR B 378 ? ARG B 380 ? THR C 378 ARG C 380 +AA7 2 HIS B 437 ? GLU B 439 ? HIS C 437 GLU C 439 +AA8 1 VAL B 479 ? LYS B 480 ? VAL C 479 LYS C 480 +AA8 2 VAL B 546 ? GLU B 547 ? VAL C 546 GLU C 547 +AA9 1 THR C 131 ? ASP C 135 ? THR B 193 ASP B 197 +AA9 2 LEU C 162 ? PHE C 166 ? LEU B 224 PHE B 228 +AA9 3 LYS C 171 ? PRO C 176 ? LYS B 233 PRO B 238 +AA9 4 LEU C 273 ? ALA C 280 ? LEU B 335 ALA B 342 +AA9 5 THR C 219 ? ASN C 225 ? THR B 281 ASN B 287 +AB1 1 PHE C 244 ? VAL C 245 ? PHE B 306 VAL B 307 +AB1 2 VAL C 251 ? PHE C 253 ? VAL B 313 PHE B 315 +AB1 3 VAL C 267 ? CYS C 268 ? VAL B 329 CYS B 330 +AB2 1 ARG C 290 ? PRO C 294 ? ARG B 352 PRO B 356 +AB2 2 HIS C 351 ? PHE C 355 ? HIS B 413 PHE B 417 +AB2 3 LEU C 364 ? ILE C 365 ? LEU B 426 ILE B 427 +AB3 1 ILE C 393 ? LYS C 394 ? ILE B 455 LYS B 456 +AB3 2 ILE C 460 ? VAL C 461 ? ILE B 522 VAL B 523 +AB4 1 ILE D 234 ? MET D 239 ? ILE D 234 MET D 239 +AB4 2 LEU D 248 ? PHE D 252 ? LEU D 248 PHE D 252 +AB4 3 GLN D 257 ? PRO D 262 ? GLN D 257 PRO D 262 +AB4 4 GLY D 362 ? ALA D 366 ? GLY D 362 ALA D 366 +AB4 5 VAL D 305 ? ARG D 308 ? VAL D 305 ARG D 308 +AB5 1 PHE D 330 ? VAL D 331 ? PHE D 330 VAL D 331 +AB5 2 ILE D 337 ? PHE D 339 ? ILE D 337 PHE D 339 +AB5 3 LEU D 353 ? CYS D 354 ? LEU D 353 CYS D 354 +AB6 1 THR D 378 ? ARG D 380 ? THR D 378 ARG D 380 +AB6 2 HIS D 437 ? GLU D 439 ? HIS D 437 GLU D 439 +AB7 1 VAL D 479 ? LYS D 480 ? VAL D 479 LYS D 480 +AB7 2 VAL D 546 ? GLU D 547 ? VAL D 546 GLU D 547 +# +loop_ +_pdbx_struct_sheet_hbond.sheet_id +_pdbx_struct_sheet_hbond.range_id_1 +_pdbx_struct_sheet_hbond.range_id_2 +_pdbx_struct_sheet_hbond.range_1_label_atom_id +_pdbx_struct_sheet_hbond.range_1_label_comp_id +_pdbx_struct_sheet_hbond.range_1_label_asym_id +_pdbx_struct_sheet_hbond.range_1_label_seq_id +_pdbx_struct_sheet_hbond.range_1_PDB_ins_code +_pdbx_struct_sheet_hbond.range_1_auth_atom_id +_pdbx_struct_sheet_hbond.range_1_auth_comp_id +_pdbx_struct_sheet_hbond.range_1_auth_asym_id +_pdbx_struct_sheet_hbond.range_1_auth_seq_id +_pdbx_struct_sheet_hbond.range_2_label_atom_id +_pdbx_struct_sheet_hbond.range_2_label_comp_id +_pdbx_struct_sheet_hbond.range_2_label_asym_id +_pdbx_struct_sheet_hbond.range_2_label_seq_id +_pdbx_struct_sheet_hbond.range_2_PDB_ins_code +_pdbx_struct_sheet_hbond.range_2_auth_atom_id +_pdbx_struct_sheet_hbond.range_2_auth_comp_id +_pdbx_struct_sheet_hbond.range_2_auth_asym_id +_pdbx_struct_sheet_hbond.range_2_auth_seq_id +AA1 1 2 N ILE A 132 ? N ILE A 194 O ARG A 165 ? O ARG A 227 +AA1 2 3 N LEU A 162 ? N LEU A 224 O PHE A 174 ? O PHE A 236 +AA1 3 4 N MET A 173 ? N MET A 235 O SER A 279 ? O SER A 341 +AA1 4 5 O LEU A 274 ? O LEU A 336 N VAL A 224 ? N VAL A 286 +AA2 1 2 N PHE A 244 ? N PHE A 306 O CYS A 252 ? O CYS A 314 +AA2 2 3 N PHE A 253 ? N PHE A 315 O VAL A 267 ? O VAL A 329 +AA3 1 2 N VAL A 293 ? N VAL A 355 O TYR A 352 ? O TYR A 414 +AA3 2 3 N GLU A 353 ? N GLU A 415 O ILE A 365 ? O ILE A 427 +AA4 1 2 N ILE A 393 ? N ILE A 455 O VAL A 461 ? O VAL A 523 +AA5 1 2 N GLY B 238 ? N GLY C 238 O ILE B 249 ? O ILE C 249 +AA5 2 3 N MET B 250 ? N MET C 250 O ALA B 258 ? O ALA C 258 +AA5 3 4 N LEU B 259 ? N LEU C 259 O ALA B 365 ? O ALA C 365 +AA5 4 5 O LEU B 364 ? O LEU C 364 N ALA B 306 ? N ALA C 306 +AA6 1 2 N PHE B 330 ? N PHE C 330 O CYS B 338 ? O CYS C 338 +AA6 2 3 N PHE B 339 ? N PHE C 339 O LEU B 353 ? O LEU C 353 +AA7 1 2 N TRP B 379 ? N TRP C 379 O TYR B 438 ? O TYR C 438 +AA8 1 2 N VAL B 479 ? N VAL C 479 O GLU B 547 ? O GLU C 547 +AA9 1 2 N ILE C 132 ? N ILE B 194 O ARG C 165 ? O ARG B 227 +AA9 2 3 N LEU C 162 ? N LEU B 224 O PHE C 174 ? O PHE B 236 +AA9 3 4 N MET C 173 ? N MET B 235 O SER C 279 ? O SER B 341 +AA9 4 5 O LEU C 274 ? O LEU B 336 N VAL C 224 ? N VAL B 286 +AB1 1 2 N PHE C 244 ? N PHE B 306 O CYS C 252 ? O CYS B 314 +AB1 2 3 N PHE C 253 ? N PHE B 315 O VAL C 267 ? O VAL B 329 +AB2 1 2 N VAL C 293 ? N VAL B 355 O TYR C 352 ? O TYR B 414 +AB2 2 3 N GLU C 353 ? N GLU B 415 O ILE C 365 ? O ILE B 427 +AB3 1 2 N ILE C 393 ? N ILE B 455 O VAL C 461 ? O VAL B 523 +AB4 1 2 N GLY D 238 ? N GLY D 238 O ILE D 249 ? O ILE D 249 +AB4 2 3 N LEU D 248 ? N LEU D 248 O PHE D 260 ? O PHE D 260 +AB4 3 4 N LEU D 259 ? N LEU D 259 O ALA D 365 ? O ALA D 365 +AB4 4 5 O LEU D 364 ? O LEU D 364 N ALA D 306 ? N ALA D 306 +AB5 1 2 N PHE D 330 ? N PHE D 330 O CYS D 338 ? O CYS D 338 +AB5 2 3 N PHE D 339 ? N PHE D 339 O LEU D 353 ? O LEU D 353 +AB6 1 2 N TRP D 379 ? N TRP D 379 O TYR D 438 ? O TYR D 438 +AB7 1 2 N VAL D 479 ? N VAL D 479 O GLU D 547 ? O GLU D 547 +# +loop_ +_struct_site.id +_struct_site.pdbx_evidence_code +_struct_site.pdbx_auth_asym_id +_struct_site.pdbx_auth_comp_id +_struct_site.pdbx_auth_seq_id +_struct_site.pdbx_auth_ins_code +_struct_site.pdbx_num_residues +_struct_site.details +AC1 Software A ATP 701 ? 16 'binding site for residue ATP A 701' +AC2 Software B ATP 701 ? 13 'binding site for residue ATP B 701' +# +loop_ +_struct_site_gen.id +_struct_site_gen.site_id +_struct_site_gen.pdbx_num_res +_struct_site_gen.label_comp_id +_struct_site_gen.label_asym_id +_struct_site_gen.label_seq_id +_struct_site_gen.pdbx_auth_ins_code +_struct_site_gen.auth_comp_id +_struct_site_gen.auth_asym_id +_struct_site_gen.auth_seq_id +_struct_site_gen.label_atom_id +_struct_site_gen.label_alt_id +_struct_site_gen.symmetry +_struct_site_gen.details +1 AC1 16 TYR A 63 ? TYR A 125 . ? 1_555 ? +2 AC1 16 LYS A 67 ? LYS A 129 . ? 1_555 ? +3 AC1 16 GLN A 138 ? GLN A 200 . ? 1_555 ? +4 AC1 16 LYS A 171 ? LYS A 233 . ? 1_555 ? +5 AC1 16 MET A 173 ? MET A 235 . ? 1_555 ? +6 AC1 16 PRO A 217 ? PRO A 279 . ? 1_555 ? +7 AC1 16 SER A 279 ? SER A 341 . ? 1_555 ? +8 AC1 16 ALA A 280 ? ALA A 342 . ? 1_555 ? +9 AC1 16 PHE A 281 ? PHE A 343 . ? 1_555 ? +10 AC1 16 LEU A 282 ? LEU A 344 . ? 1_555 ? +11 AC1 16 SER A 284 ? SER A 346 . ? 1_555 ? +12 AC1 16 LEU A 285 ? LEU A 347 . ? 1_555 ? +13 AC1 16 ASN A 286 ? ASN A 348 . ? 1_555 ? +14 AC1 16 ARG A 290 ? ARG A 352 . ? 1_555 ? +15 AC1 16 ASP A 368 ? ASP A 430 . ? 1_555 ? +16 AC1 16 LYS D 170 ? LYS D 170 . ? 1_555 ? +17 AC2 13 TYR C 63 ? TYR B 125 . ? 1_555 ? +18 AC2 13 LYS C 67 ? LYS B 129 . ? 1_555 ? +19 AC2 13 LYS C 171 ? LYS B 233 . ? 1_555 ? +20 AC2 13 PRO C 217 ? PRO B 279 . ? 1_555 ? +21 AC2 13 SER C 279 ? SER B 341 . ? 1_555 ? +22 AC2 13 ALA C 280 ? ALA B 342 . ? 1_555 ? +23 AC2 13 PHE C 281 ? PHE B 343 . ? 1_555 ? +24 AC2 13 LEU C 282 ? LEU B 344 . ? 1_555 ? +25 AC2 13 SER C 284 ? SER B 346 . ? 1_555 ? +26 AC2 13 LEU C 285 ? LEU B 347 . ? 1_555 ? +27 AC2 13 ASN C 286 ? ASN B 348 . ? 1_555 ? +28 AC2 13 ARG C 290 ? ARG B 352 . ? 1_555 ? +29 AC2 13 LYS B 170 ? LYS C 170 . ? 1_555 ? +# +_atom_sites.entry_id 5YH2 +_atom_sites.fract_transf_matrix[1][1] 0.009086 +_atom_sites.fract_transf_matrix[1][2] 0.000000 +_atom_sites.fract_transf_matrix[1][3] 0.000000 +_atom_sites.fract_transf_matrix[2][1] 0.000000 +_atom_sites.fract_transf_matrix[2][2] 0.009086 +_atom_sites.fract_transf_matrix[2][3] 0.000000 +_atom_sites.fract_transf_matrix[3][1] 0.000000 +_atom_sites.fract_transf_matrix[3][2] 0.000000 +_atom_sites.fract_transf_matrix[3][3] 0.002166 +_atom_sites.fract_transf_vector[1] 0.00000 +_atom_sites.fract_transf_vector[2] 0.00000 +_atom_sites.fract_transf_vector[3] 0.00000 +# +loop_ +_atom_type.symbol +C +N +O +P +S +# +loop_ +_atom_site.group_PDB +_atom_site.id +_atom_site.type_symbol +_atom_site.label_atom_id +_atom_site.label_alt_id +_atom_site.label_comp_id +_atom_site.label_asym_id +_atom_site.label_entity_id +_atom_site.label_seq_id +_atom_site.pdbx_PDB_ins_code +_atom_site.Cartn_x +_atom_site.Cartn_y +_atom_site.Cartn_z +_atom_site.occupancy +_atom_site.B_iso_or_equiv +_atom_site.pdbx_formal_charge +_atom_site.auth_seq_id +_atom_site.auth_comp_id +_atom_site.auth_asym_id +_atom_site.auth_atom_id +_atom_site.pdbx_PDB_model_num +ATOM 1 N N . SER A 1 27 ? -50.080 17.388 -22.113 1.00 69.45 ? 89 SER A N 1 +ATOM 2 C CA . SER A 1 27 ? -49.351 16.577 -23.081 1.00 68.09 ? 89 SER A CA 1 +ATOM 3 C C . SER A 1 27 ? -50.270 15.578 -23.790 1.00 71.23 ? 89 SER A C 1 +ATOM 4 O O . SER A 1 27 ? -51.412 15.362 -23.369 1.00 66.77 ? 89 SER A O 1 +ATOM 5 C CB . SER A 1 27 ? -48.200 15.834 -22.397 1.00 60.76 ? 89 SER A CB 1 +ATOM 6 O OG . SER A 1 27 ? -47.294 16.738 -21.791 1.00 60.76 ? 89 SER A OG 1 +ATOM 7 N N . SER A 1 28 ? -49.768 15.001 -24.886 1.00 74.47 ? 90 SER A N 1 +ATOM 8 C CA . SER A 1 28 ? -50.488 13.988 -25.654 1.00 70.57 ? 90 SER A CA 1 +ATOM 9 C C . SER A 1 28 ? -51.820 14.505 -26.177 1.00 65.72 ? 90 SER A C 1 +ATOM 10 O O . SER A 1 28 ? -52.858 14.329 -25.528 1.00 58.64 ? 90 SER A O 1 +ATOM 11 C CB . SER A 1 28 ? -50.721 12.725 -24.820 1.00 64.97 ? 90 SER A CB 1 +ATOM 12 O OG . SER A 1 28 ? -51.550 11.811 -25.518 1.00 56.14 ? 90 SER A OG 1 +ATOM 13 N N . LYS A 1 29 ? -51.801 15.141 -27.352 1.00 65.14 ? 91 LYS A N 1 +ATOM 14 C CA . LYS A 1 29 ? -53.048 15.588 -27.957 1.00 58.33 ? 91 LYS A CA 1 +ATOM 15 C C . LYS A 1 29 ? -53.914 14.419 -28.403 1.00 50.96 ? 91 LYS A C 1 +ATOM 16 O O . LYS A 1 29 ? -55.133 14.577 -28.523 1.00 45.72 ? 91 LYS A O 1 +ATOM 17 C CB . LYS A 1 29 ? -52.767 16.506 -29.148 1.00 49.49 ? 91 LYS A CB 1 +ATOM 18 C CG . LYS A 1 29 ? -52.050 17.789 -28.789 1.00 52.35 ? 91 LYS A CG 1 +ATOM 19 C CD . LYS A 1 29 ? -51.806 18.648 -30.019 1.00 50.79 ? 91 LYS A CD 1 +ATOM 20 C CE . LYS A 1 29 ? -50.808 19.757 -29.733 1.00 51.10 ? 91 LYS A CE 1 +ATOM 21 N NZ . LYS A 1 29 ? -51.303 21.056 -30.271 1.00 59.36 ? 91 LYS A NZ 1 +ATOM 22 N N . LEU A 1 30 ? -53.320 13.244 -28.619 1.00 52.59 ? 92 LEU A N 1 +ATOM 23 C CA . LEU A 1 30 ? -54.109 12.101 -29.061 1.00 54.16 ? 92 LEU A CA 1 +ATOM 24 C C . LEU A 1 30 ? -55.051 11.637 -27.956 1.00 53.23 ? 92 LEU A C 1 +ATOM 25 O O . LEU A 1 30 ? -56.246 11.425 -28.199 1.00 49.37 ? 92 LEU A O 1 +ATOM 26 C CB . LEU A 1 30 ? -53.183 10.967 -29.520 1.00 46.72 ? 92 LEU A CB 1 +ATOM 27 C CG . LEU A 1 30 ? -53.723 9.889 -30.474 1.00 39.69 ? 92 LEU A CG 1 +ATOM 28 C CD1 . LEU A 1 30 ? -54.374 8.755 -29.719 1.00 48.43 ? 92 LEU A CD1 1 +ATOM 29 C CD2 . LEU A 1 30 ? -54.710 10.465 -31.462 1.00 38.00 ? 92 LEU A CD2 1 +ATOM 30 N N . GLN A 1 31 ? -54.539 11.521 -26.723 1.00 52.43 ? 93 GLN A N 1 +ATOM 31 C CA . GLN A 1 31 ? -55.379 11.096 -25.604 1.00 50.58 ? 93 GLN A CA 1 +ATOM 32 C C . GLN A 1 31 ? -56.489 12.096 -25.326 1.00 47.74 ? 93 GLN A C 1 +ATOM 33 O O . GLN A 1 31 ? -57.610 11.706 -24.978 1.00 44.00 ? 93 GLN A O 1 +ATOM 34 C CB . GLN A 1 31 ? -54.533 10.887 -24.353 1.00 45.16 ? 93 GLN A CB 1 +ATOM 35 C CG . GLN A 1 31 ? -53.619 9.694 -24.443 1.00 51.45 ? 93 GLN A CG 1 +ATOM 36 C CD . GLN A 1 31 ? -52.877 9.421 -23.153 1.00 59.38 ? 93 GLN A CD 1 +ATOM 37 O OE1 . GLN A 1 31 ? -53.076 10.107 -22.145 1.00 60.26 ? 93 GLN A OE1 1 +ATOM 38 N NE2 . GLN A 1 31 ? -52.016 8.408 -23.175 1.00 52.88 ? 93 GLN A NE2 1 +ATOM 39 N N . ALA A 1 32 ? -56.199 13.389 -25.472 1.00 47.63 ? 94 ALA A N 1 +ATOM 40 C CA . ALA A 1 32 ? -57.234 14.392 -25.265 1.00 46.64 ? 94 ALA A CA 1 +ATOM 41 C C . ALA A 1 32 ? -58.347 14.261 -26.295 1.00 45.67 ? 94 ALA A C 1 +ATOM 42 O O . ALA A 1 32 ? -59.513 14.529 -25.981 1.00 45.43 ? 94 ALA A O 1 +ATOM 43 C CB . ALA A 1 32 ? -56.627 15.794 -25.308 1.00 45.28 ? 94 ALA A CB 1 +ATOM 44 N N . LEU A 1 33 ? -58.017 13.824 -27.516 1.00 40.15 ? 95 LEU A N 1 +ATOM 45 C CA . LEU A 1 33 ? -59.033 13.727 -28.560 1.00 40.12 ? 95 LEU A CA 1 +ATOM 46 C C . LEU A 1 33 ? -60.082 12.685 -28.210 1.00 44.07 ? 95 LEU A C 1 +ATOM 47 O O . LEU A 1 33 ? -61.285 12.965 -28.244 1.00 47.72 ? 95 LEU A O 1 +ATOM 48 C CB . LEU A 1 33 ? -58.397 13.406 -29.915 1.00 42.16 ? 95 LEU A CB 1 +ATOM 49 C CG . LEU A 1 33 ? -59.382 13.437 -31.095 1.00 38.00 ? 95 LEU A CG 1 +ATOM 50 C CD1 . LEU A 1 33 ? -60.050 14.774 -31.171 1.00 38.00 ? 95 LEU A CD1 1 +ATOM 51 C CD2 . LEU A 1 33 ? -58.697 13.149 -32.416 1.00 38.00 ? 95 LEU A CD2 1 +ATOM 52 N N . PHE A 1 34 ? -59.650 11.475 -27.870 1.00 43.71 ? 96 PHE A N 1 +ATOM 53 C CA . PHE A 1 34 ? -60.619 10.421 -27.618 1.00 46.56 ? 96 PHE A CA 1 +ATOM 54 C C . PHE A 1 34 ? -61.295 10.562 -26.263 1.00 43.27 ? 96 PHE A C 1 +ATOM 55 O O . PHE A 1 34 ? -62.347 9.952 -26.048 1.00 48.90 ? 96 PHE A O 1 +ATOM 56 C CB . PHE A 1 34 ? -59.946 9.055 -27.760 1.00 51.04 ? 96 PHE A CB 1 +ATOM 57 C CG . PHE A 1 34 ? -59.502 8.747 -29.170 1.00 56.37 ? 96 PHE A CG 1 +ATOM 58 C CD1 . PHE A 1 34 ? -60.428 8.369 -30.134 1.00 48.00 ? 96 PHE A CD1 1 +ATOM 59 C CD2 . PHE A 1 34 ? -58.166 8.844 -29.534 1.00 51.88 ? 96 PHE A CD2 1 +ATOM 60 C CE1 . PHE A 1 34 ? -60.031 8.091 -31.426 1.00 43.76 ? 96 PHE A CE1 1 +ATOM 61 C CE2 . PHE A 1 34 ? -57.763 8.564 -30.830 1.00 43.47 ? 96 PHE A CE2 1 +ATOM 62 C CZ . PHE A 1 34 ? -58.698 8.187 -31.774 1.00 44.64 ? 96 PHE A CZ 1 +ATOM 63 N N . ALA A 1 35 ? -60.744 11.373 -25.364 1.00 38.99 ? 97 ALA A N 1 +ATOM 64 C CA . ALA A 1 35 ? -61.384 11.672 -24.091 1.00 40.19 ? 97 ALA A CA 1 +ATOM 65 C C . ALA A 1 35 ? -62.299 12.888 -24.170 1.00 40.83 ? 97 ALA A C 1 +ATOM 66 O O . ALA A 1 35 ? -62.807 13.340 -23.139 1.00 38.33 ? 97 ALA A O 1 +ATOM 67 C CB . ALA A 1 35 ? -60.328 11.881 -23.005 1.00 45.41 ? 97 ALA A CB 1 +ATOM 68 N N . HIS A 1 36 ? -62.515 13.418 -25.353 1.00 39.35 ? 98 HIS A N 1 +ATOM 69 C CA . HIS A 1 36 ? -63.402 14.548 -25.539 1.00 40.46 ? 98 HIS A CA 1 +ATOM 70 C C . HIS A 1 36 ? -64.853 14.078 -25.503 1.00 40.76 ? 98 HIS A C 1 +ATOM 71 O O . HIS A 1 36 ? -65.151 12.953 -25.906 1.00 44.67 ? 98 HIS A O 1 +ATOM 72 C CB . HIS A 1 36 ? -63.108 15.222 -26.876 1.00 45.49 ? 98 HIS A CB 1 +ATOM 73 C CG . HIS A 1 36 ? -63.755 16.561 -27.043 1.00 45.74 ? 98 HIS A CG 1 +ATOM 74 N ND1 . HIS A 1 36 ? -65.049 16.710 -27.493 1.00 39.79 ? 98 HIS A ND1 1 +ATOM 75 C CD2 . HIS A 1 36 ? -63.275 17.812 -26.850 1.00 45.30 ? 98 HIS A CD2 1 +ATOM 76 C CE1 . HIS A 1 36 ? -65.346 17.996 -27.549 1.00 41.06 ? 98 HIS A CE1 1 +ATOM 77 N NE2 . HIS A 1 36 ? -64.287 18.685 -27.164 1.00 48.52 ? 98 HIS A NE2 1 +ATOM 78 N N . PRO A 1 37 ? -65.768 14.913 -25.006 1.00 41.12 ? 99 PRO A N 1 +ATOM 79 C CA . PRO A 1 37 ? -67.188 14.524 -24.983 1.00 43.92 ? 99 PRO A CA 1 +ATOM 80 C C . PRO A 1 37 ? -67.725 14.088 -26.332 1.00 49.69 ? 99 PRO A C 1 +ATOM 81 O O . PRO A 1 37 ? -68.725 13.363 -26.383 1.00 50.43 ? 99 PRO A O 1 +ATOM 82 C CB . PRO A 1 37 ? -67.890 15.801 -24.505 1.00 46.05 ? 99 PRO A CB 1 +ATOM 83 C CG . PRO A 1 37 ? -66.879 16.488 -23.682 1.00 50.74 ? 99 PRO A CG 1 +ATOM 84 C CD . PRO A 1 37 ? -65.539 16.188 -24.308 1.00 48.48 ? 99 PRO A CD 1 +ATOM 85 N N . LEU A 1 38 ? -67.127 14.557 -27.430 1.00 46.92 ? 100 LEU A N 1 +ATOM 86 C CA . LEU A 1 38 ? -67.583 14.149 -28.754 1.00 51.50 ? 100 LEU A CA 1 +ATOM 87 C C . LEU A 1 38 ? -67.324 12.667 -28.998 1.00 52.64 ? 100 LEU A C 1 +ATOM 88 O O . LEU A 1 38 ? -68.184 11.957 -29.534 1.00 59.97 ? 100 LEU A O 1 +ATOM 89 C CB . LEU A 1 38 ? -66.916 14.999 -29.833 1.00 53.41 ? 100 LEU A CB 1 +ATOM 90 C CG . LEU A 1 38 ? -67.877 15.877 -30.633 1.00 48.66 ? 100 LEU A CG 1 +ATOM 91 C CD1 . LEU A 1 38 ? -67.111 16.662 -31.683 1.00 44.28 ? 100 LEU A CD1 1 +ATOM 92 C CD2 . LEU A 1 38 ? -68.983 15.034 -31.268 1.00 42.00 ? 100 LEU A CD2 1 +ATOM 93 N N . TYR A 1 39 ? -66.134 12.188 -28.640 1.00 45.87 ? 101 TYR A N 1 +ATOM 94 C CA . TYR A 1 39 ? -65.774 10.790 -28.853 1.00 48.87 ? 101 TYR A CA 1 +ATOM 95 C C . TYR A 1 39 ? -66.272 9.887 -27.727 1.00 52.48 ? 101 TYR A C 1 +ATOM 96 O O . TYR A 1 39 ? -65.628 8.882 -27.405 1.00 48.53 ? 101 TYR A O 1 +ATOM 97 C CB . TYR A 1 39 ? -64.258 10.661 -29.005 1.00 44.37 ? 101 TYR A CB 1 +ATOM 98 C CG . TYR A 1 39 ? -63.712 11.325 -30.247 1.00 45.79 ? 101 TYR A CG 1 +ATOM 99 C CD1 . TYR A 1 39 ? -63.608 12.705 -30.343 1.00 44.15 ? 101 TYR A CD1 1 +ATOM 100 C CD2 . TYR A 1 39 ? -63.286 10.563 -31.323 1.00 48.82 ? 101 TYR A CD2 1 +ATOM 101 C CE1 . TYR A 1 39 ? -63.108 13.304 -31.486 1.00 45.11 ? 101 TYR A CE1 1 +ATOM 102 C CE2 . TYR A 1 39 ? -62.782 11.150 -32.462 1.00 45.56 ? 101 TYR A CE2 1 +ATOM 103 C CZ . TYR A 1 39 ? -62.693 12.518 -32.542 1.00 41.92 ? 101 TYR A CZ 1 +ATOM 104 O OH . TYR A 1 39 ? -62.191 13.088 -33.690 1.00 38.00 ? 101 TYR A OH 1 +ATOM 105 N N . ASN A 1 40 ? -67.432 10.219 -27.147 1.00 51.44 ? 102 ASN A N 1 +ATOM 106 C CA . ASN A 1 40 ? -67.961 9.485 -26.001 1.00 48.87 ? 102 ASN A CA 1 +ATOM 107 C C . ASN A 1 40 ? -69.485 9.487 -25.967 1.00 52.22 ? 102 ASN A C 1 +ATOM 108 O O . ASN A 1 40 ? -70.095 8.658 -25.282 1.00 53.16 ? 102 ASN A O 1 +ATOM 109 C CB . ASN A 1 40 ? -67.428 10.081 -24.702 1.00 43.16 ? 102 ASN A CB 1 +ATOM 110 C CG . ASN A 1 40 ? -66.012 9.664 -24.417 1.00 44.58 ? 102 ASN A CG 1 +ATOM 111 O OD1 . ASN A 1 40 ? -65.662 8.489 -24.547 1.00 50.15 ? 102 ASN A OD1 1 +ATOM 112 N ND2 . ASN A 1 40 ? -65.179 10.625 -24.041 1.00 44.72 ? 102 ASN A ND2 1 +ATOM 113 N N . VAL A 1 41 ? -70.106 10.434 -26.659 1.00 53.17 ? 103 VAL A N 1 +ATOM 114 C CA . VAL A 1 41 ? -71.572 10.469 -26.693 1.00 59.33 ? 103 VAL A CA 1 +ATOM 115 C C . VAL A 1 41 ? -72.080 9.235 -27.426 1.00 61.62 ? 103 VAL A C 1 +ATOM 116 O O . VAL A 1 41 ? -71.441 8.794 -28.397 1.00 68.04 ? 103 VAL A O 1 +ATOM 117 C CB . VAL A 1 41 ? -72.063 11.751 -27.368 1.00 55.92 ? 103 VAL A CB 1 +ATOM 118 C CG1 . VAL A 1 41 ? -71.854 12.951 -26.450 1.00 64.85 ? 103 VAL A CG1 1 +ATOM 119 C CG2 . VAL A 1 41 ? -71.344 11.955 -28.684 1.00 48.69 ? 103 VAL A CG2 1 +ATOM 120 N N . PRO A 1 42 ? -73.190 8.636 -26.998 1.00 62.12 ? 104 PRO A N 1 +ATOM 121 C CA . PRO A 1 42 ? -73.728 7.476 -27.721 1.00 70.65 ? 104 PRO A CA 1 +ATOM 122 C C . PRO A 1 42 ? -74.178 7.841 -29.132 1.00 85.13 ? 104 PRO A C 1 +ATOM 123 O O . PRO A 1 42 ? -74.672 8.942 -29.390 1.00 84.66 ? 104 PRO A O 1 +ATOM 124 C CB . PRO A 1 42 ? -74.912 7.033 -26.851 1.00 70.44 ? 104 PRO A CB 1 +ATOM 125 C CG . PRO A 1 42 ? -74.625 7.609 -25.494 1.00 68.68 ? 104 PRO A CG 1 +ATOM 126 C CD . PRO A 1 42 ? -73.914 8.900 -25.745 1.00 61.41 ? 104 PRO A CD 1 +ATOM 127 N N . GLU A 1 43 ? -74.028 6.881 -30.044 1.00 86.85 ? 105 GLU A N 1 +ATOM 128 C CA . GLU A 1 43 ? -74.381 7.071 -31.446 1.00 71.98 ? 105 GLU A CA 1 +ATOM 129 C C . GLU A 1 43 ? -75.826 6.658 -31.665 1.00 76.27 ? 105 GLU A C 1 +ATOM 130 O O . GLU A 1 43 ? -76.253 5.595 -31.202 1.00 84.62 ? 105 GLU A O 1 +ATOM 131 C CB . GLU A 1 43 ? -73.466 6.251 -32.358 1.00 70.10 ? 105 GLU A CB 1 +ATOM 132 C CG . GLU A 1 43 ? -72.267 6.998 -32.916 1.00 73.16 ? 105 GLU A CG 1 +ATOM 133 C CD . GLU A 1 43 ? -71.322 6.083 -33.678 1.00 65.73 ? 105 GLU A CD 1 +ATOM 134 O OE1 . GLU A 1 43 ? -70.974 5.012 -33.135 1.00 67.29 ? 105 GLU A OE1 1 +ATOM 135 O OE2 . GLU A 1 43 ? -70.929 6.432 -34.815 1.00 56.61 ? 105 GLU A OE2 1 +ATOM 136 N N . GLU A 1 44 ? -76.566 7.490 -32.362 1.00 84.85 ? 106 GLU A N 1 +ATOM 137 C CA . GLU A 1 44 ? -77.963 7.187 -32.609 1.00 93.04 ? 106 GLU A CA 1 +ATOM 138 C C . GLU A 1 44 ? -78.175 6.794 -34.067 1.00 95.40 ? 106 GLU A C 1 +ATOM 139 O O . GLU A 1 44 ? -77.509 7.338 -34.956 1.00 98.77 ? 106 GLU A O 1 +ATOM 140 C CB . GLU A 1 44 ? -78.853 8.385 -32.259 1.00 96.92 ? 106 GLU A CB 1 +ATOM 141 C CG . GLU A 1 44 ? -78.521 8.996 -30.904 1.00 96.11 ? 106 GLU A CG 1 +ATOM 142 C CD . GLU A 1 44 ? -78.931 8.110 -29.739 1.00 92.77 ? 106 GLU A CD 1 +ATOM 143 O OE1 . GLU A 1 44 ? -79.662 7.121 -29.962 1.00 89.74 ? 106 GLU A OE1 1 +ATOM 144 O OE2 . GLU A 1 44 ? -78.507 8.396 -28.599 1.00 92.12 ? 106 GLU A OE2 1 +ATOM 145 N N . PRO A 1 45 ? -79.086 5.848 -34.351 1.00 91.33 ? 107 PRO A N 1 +ATOM 146 C CA . PRO A 1 45 ? -79.866 5.083 -33.371 1.00 86.80 ? 107 PRO A CA 1 +ATOM 147 C C . PRO A 1 45 ? -79.039 3.998 -32.692 1.00 86.31 ? 107 PRO A C 1 +ATOM 148 O O . PRO A 1 45 ? -78.074 3.517 -33.286 1.00 83.88 ? 107 PRO A O 1 +ATOM 149 C CB . PRO A 1 45 ? -80.980 4.451 -34.221 1.00 93.35 ? 107 PRO A CB 1 +ATOM 150 C CG . PRO A 1 45 ? -80.973 5.211 -35.513 1.00 98.31 ? 107 PRO A CG 1 +ATOM 151 C CD . PRO A 1 45 ? -79.544 5.587 -35.723 1.00 93.88 ? 107 PRO A CD 1 +ATOM 152 N N . PRO A 1 46 ? -79.430 3.598 -31.484 1.00 87.58 ? 108 PRO A N 1 +ATOM 153 C CA . PRO A 1 46 ? -78.714 2.518 -30.793 1.00 88.98 ? 108 PRO A CA 1 +ATOM 154 C C . PRO A 1 46 ? -78.944 1.178 -31.480 1.00 95.70 ? 108 PRO A C 1 +ATOM 155 O O . PRO A 1 46 ? -79.831 1.013 -32.321 1.00 100.27 ? 108 PRO A O 1 +ATOM 156 C CB . PRO A 1 46 ? -79.299 2.530 -29.377 1.00 74.95 ? 108 PRO A CB 1 +ATOM 157 C CG . PRO A 1 46 ? -80.121 3.788 -29.280 1.00 73.50 ? 108 PRO A CG 1 +ATOM 158 C CD . PRO A 1 46 ? -80.515 4.164 -30.668 1.00 78.06 ? 108 PRO A CD 1 +ATOM 159 N N . LEU A 1 47 ? -78.117 0.205 -31.105 1.00 90.31 ? 109 LEU A N 1 +ATOM 160 C CA . LEU A 1 47 ? -78.110 -1.105 -31.745 1.00 90.40 ? 109 LEU A CA 1 +ATOM 161 C C . LEU A 1 47 ? -78.939 -2.084 -30.924 1.00 97.39 ? 109 LEU A C 1 +ATOM 162 O O . LEU A 1 47 ? -78.658 -2.302 -29.741 1.00 96.31 ? 109 LEU A O 1 +ATOM 163 C CB . LEU A 1 47 ? -76.681 -1.626 -31.906 1.00 79.04 ? 109 LEU A CB 1 +ATOM 164 C CG . LEU A 1 47 ? -75.643 -0.656 -32.471 1.00 73.46 ? 109 LEU A CG 1 +ATOM 165 C CD1 . LEU A 1 47 ? -74.252 -1.252 -32.366 1.00 56.89 ? 109 LEU A CD1 1 +ATOM 166 C CD2 . LEU A 1 47 ? -75.974 -0.314 -33.911 1.00 79.24 ? 109 LEU A CD2 1 +ATOM 167 N N . LEU A 1 48 ? -79.966 -2.666 -31.552 1.00 104.65 ? 110 LEU A N 1 +ATOM 168 C CA . LEU A 1 48 ? -80.746 -3.704 -30.889 1.00 102.24 ? 110 LEU A CA 1 +ATOM 169 C C . LEU A 1 48 ? -79.993 -5.026 -30.829 1.00 96.60 ? 110 LEU A C 1 +ATOM 170 O O . LEU A 1 48 ? -80.301 -5.862 -29.973 1.00 92.57 ? 110 LEU A O 1 +ATOM 171 C CB . LEU A 1 48 ? -82.099 -3.898 -31.584 1.00 96.49 ? 110 LEU A CB 1 +ATOM 172 C CG . LEU A 1 48 ? -82.327 -3.352 -32.996 1.00 105.11 ? 110 LEU A CG 1 +ATOM 173 C CD1 . LEU A 1 48 ? -83.325 -4.224 -33.755 1.00 107.86 ? 110 LEU A CD1 1 +ATOM 174 C CD2 . LEU A 1 48 ? -82.821 -1.909 -32.944 1.00 102.89 ? 110 LEU A CD2 1 +ATOM 175 N N . GLY A 1 49 ? -79.016 -5.231 -31.711 1.00 91.19 ? 111 GLY A N 1 +ATOM 176 C CA . GLY A 1 49 ? -78.296 -6.485 -31.769 1.00 98.71 ? 111 GLY A CA 1 +ATOM 177 C C . GLY A 1 49 ? -78.877 -7.435 -32.794 1.00 104.44 ? 111 GLY A C 1 +ATOM 178 O O . GLY A 1 49 ? -79.901 -7.177 -33.436 1.00 103.41 ? 111 GLY A O 1 +ATOM 179 N N . ALA A 1 50 ? -78.185 -8.564 -32.955 1.00 101.90 ? 112 ALA A N 1 +ATOM 180 C CA . ALA A 1 50 ? -78.594 -9.613 -33.883 1.00 101.99 ? 112 ALA A CA 1 +ATOM 181 C C . ALA A 1 50 ? -78.729 -9.082 -35.308 1.00 105.42 ? 112 ALA A C 1 +ATOM 182 O O . ALA A 1 50 ? -77.913 -9.413 -36.174 1.00 109.31 ? 112 ALA A O 1 +ATOM 183 C CB . ALA A 1 50 ? -79.905 -10.255 -33.416 1.00 98.35 ? 112 ALA A CB 1 +ATOM 184 N N . GLU A 1 51 ? -79.739 -8.244 -35.561 1.00 101.98 ? 113 GLU A N 1 +ATOM 185 C CA . GLU A 1 51 ? -79.957 -7.711 -36.899 1.00 97.28 ? 113 GLU A CA 1 +ATOM 186 C C . GLU A 1 51 ? -79.072 -6.513 -37.208 1.00 96.01 ? 113 GLU A C 1 +ATOM 187 O O . GLU A 1 51 ? -79.061 -6.051 -38.354 1.00 94.07 ? 113 GLU A O 1 +ATOM 188 C CB . GLU A 1 51 ? -81.427 -7.313 -37.090 1.00 92.82 ? 113 GLU A CB 1 +ATOM 189 C CG . GLU A 1 51 ? -82.434 -8.409 -36.765 1.00 103.32 ? 113 GLU A CG 1 +ATOM 190 C CD . GLU A 1 51 ? -82.760 -8.491 -35.284 1.00 112.47 ? 113 GLU A CD 1 +ATOM 191 O OE1 . GLU A 1 51 ? -82.583 -7.476 -34.576 1.00 110.55 ? 113 GLU A OE1 1 +ATOM 192 O OE2 . GLU A 1 51 ? -83.196 -9.571 -34.829 1.00 106.98 ? 113 GLU A OE2 1 +ATOM 193 N N . ASP A 1 52 ? -78.308 -6.020 -36.235 1.00 93.45 ? 114 ASP A N 1 +ATOM 194 C CA . ASP A 1 52 ? -77.398 -4.904 -36.451 1.00 85.85 ? 114 ASP A CA 1 +ATOM 195 C C . ASP A 1 52 ? -75.939 -5.343 -36.445 1.00 76.49 ? 114 ASP A C 1 +ATOM 196 O O . ASP A 1 52 ? -75.045 -4.494 -36.512 1.00 73.93 ? 114 ASP A O 1 +ATOM 197 C CB . ASP A 1 52 ? -77.637 -3.822 -35.393 1.00 88.87 ? 114 ASP A CB 1 +ATOM 198 C CG . ASP A 1 52 ? -78.980 -3.120 -35.560 1.00 85.26 ? 114 ASP A CG 1 +ATOM 199 O OD1 . ASP A 1 52 ? -79.685 -3.400 -36.552 1.00 82.36 ? 114 ASP A OD1 1 +ATOM 200 O OD2 . ASP A 1 52 ? -79.340 -2.298 -34.687 1.00 86.07 ? 114 ASP A OD2 1 +ATOM 201 N N . SER A 1 53 ? -75.682 -6.649 -36.400 1.00 72.24 ? 115 SER A N 1 +ATOM 202 C CA . SER A 1 53 ? -74.342 -7.217 -36.539 1.00 75.41 ? 115 SER A CA 1 +ATOM 203 C C . SER A 1 53 ? -74.359 -8.078 -37.794 1.00 76.04 ? 115 SER A C 1 +ATOM 204 O O . SER A 1 53 ? -75.092 -9.070 -37.856 1.00 83.27 ? 115 SER A O 1 +ATOM 205 C CB . SER A 1 53 ? -73.940 -8.039 -35.312 1.00 76.92 ? 115 SER A CB 1 +ATOM 206 O OG . SER A 1 53 ? -73.428 -7.222 -34.273 1.00 69.35 ? 115 SER A OG 1 +ATOM 207 N N . LEU A 1 54 ? -73.588 -7.678 -38.810 1.00 68.67 ? 116 LEU A N 1 +ATOM 208 C CA . LEU A 1 54 ? -73.691 -8.337 -40.109 1.00 64.93 ? 116 LEU A CA 1 +ATOM 209 C C . LEU A 1 54 ? -73.308 -9.810 -40.055 1.00 65.30 ? 116 LEU A C 1 +ATOM 210 O O . LEU A 1 54 ? -73.712 -10.572 -40.940 1.00 71.04 ? 116 LEU A O 1 +ATOM 211 C CB . LEU A 1 54 ? -72.850 -7.604 -41.158 1.00 62.82 ? 116 LEU A CB 1 +ATOM 212 C CG . LEU A 1 54 ? -71.341 -7.394 -41.022 1.00 62.35 ? 116 LEU A CG 1 +ATOM 213 C CD1 . LEU A 1 54 ? -70.544 -8.658 -41.298 1.00 59.98 ? 116 LEU A CD1 1 +ATOM 214 C CD2 . LEU A 1 54 ? -70.914 -6.298 -41.973 1.00 60.11 ? 116 LEU A CD2 1 +ATOM 215 N N . LEU A 1 55 ? -72.535 -10.228 -39.059 1.00 65.20 ? 117 LEU A N 1 +ATOM 216 C CA . LEU A 1 55 ? -72.116 -11.617 -38.934 1.00 66.13 ? 117 LEU A CA 1 +ATOM 217 C C . LEU A 1 55 ? -72.902 -12.291 -37.814 1.00 75.65 ? 117 LEU A C 1 +ATOM 218 O O . LEU A 1 55 ? -72.884 -11.825 -36.669 1.00 79.71 ? 117 LEU A O 1 +ATOM 219 C CB . LEU A 1 55 ? -70.612 -11.700 -38.669 1.00 58.78 ? 117 LEU A CB 1 +ATOM 220 C CG . LEU A 1 55 ? -69.857 -12.670 -39.578 1.00 55.22 ? 117 LEU A CG 1 +ATOM 221 C CD1 . LEU A 1 55 ? -70.019 -12.263 -41.031 1.00 56.44 ? 117 LEU A CD1 1 +ATOM 222 C CD2 . LEU A 1 55 ? -68.389 -12.753 -39.201 1.00 50.02 ? 117 LEU A CD2 1 +ATOM 223 N N . ALA A 1 56 ? -73.590 -13.384 -38.145 1.00 75.45 ? 118 ALA A N 1 +ATOM 224 C CA . ALA A 1 56 ? -74.263 -14.193 -37.136 1.00 74.90 ? 118 ALA A CA 1 +ATOM 225 C C . ALA A 1 56 ? -73.253 -15.108 -36.451 1.00 75.36 ? 118 ALA A C 1 +ATOM 226 O O . ALA A 1 56 ? -72.476 -15.799 -37.116 1.00 70.64 ? 118 ALA A O 1 +ATOM 227 C CB . ALA A 1 56 ? -75.389 -15.016 -37.762 1.00 75.86 ? 118 ALA A CB 1 +ATOM 228 N N . SER A 1 57 ? -73.277 -15.111 -35.116 1.00 81.64 ? 119 SER A N 1 +ATOM 229 C CA . SER A 1 57 ? -72.243 -15.781 -34.330 1.00 77.24 ? 119 SER A CA 1 +ATOM 230 C C . SER A 1 57 ? -72.185 -17.278 -34.627 1.00 76.83 ? 119 SER A C 1 +ATOM 231 O O . SER A 1 57 ? -71.121 -17.822 -34.938 1.00 68.36 ? 119 SER A O 1 +ATOM 232 C CB . SER A 1 57 ? -72.480 -15.525 -32.837 1.00 76.74 ? 119 SER A CB 1 +ATOM 233 O OG . SER A 1 57 ? -73.839 -15.727 -32.478 1.00 78.07 ? 119 SER A OG 1 +ATOM 234 N N . GLN A 1 58 ? -73.319 -17.971 -34.495 1.00 85.88 ? 120 GLN A N 1 +ATOM 235 C CA . GLN A 1 58 ? -73.312 -19.424 -34.646 1.00 86.56 ? 120 GLN A CA 1 +ATOM 236 C C . GLN A 1 58 ? -72.981 -19.840 -36.077 1.00 85.74 ? 120 GLN A C 1 +ATOM 237 O O . GLN A 1 58 ? -72.226 -20.797 -36.292 1.00 79.26 ? 120 GLN A O 1 +ATOM 238 C CB . GLN A 1 58 ? -74.666 -19.999 -34.223 1.00 94.83 ? 120 GLN A CB 1 +ATOM 239 C CG . GLN A 1 58 ? -74.660 -21.505 -33.988 1.00 92.72 ? 120 GLN A CG 1 +ATOM 240 C CD . GLN A 1 58 ? -76.055 -22.092 -33.865 1.00 92.83 ? 120 GLN A CD 1 +ATOM 241 O OE1 . GLN A 1 58 ? -76.795 -22.188 -34.848 1.00 85.40 ? 120 GLN A OE1 1 +ATOM 242 N NE2 . GLN A 1 58 ? -76.424 -22.481 -32.649 1.00 93.97 ? 120 GLN A NE2 1 +ATOM 243 N N . GLU A 1 59 ? -73.509 -19.117 -37.067 1.00 84.96 ? 121 GLU A N 1 +ATOM 244 C CA . GLU A 1 59 ? -73.269 -19.492 -38.456 1.00 76.25 ? 121 GLU A CA 1 +ATOM 245 C C . GLU A 1 59 ? -71.836 -19.198 -38.875 1.00 70.74 ? 121 GLU A C 1 +ATOM 246 O O . GLU A 1 59 ? -71.211 -20.009 -39.567 1.00 71.82 ? 121 GLU A O 1 +ATOM 247 C CB . GLU A 1 59 ? -74.250 -18.769 -39.373 1.00 77.07 ? 121 GLU A CB 1 +ATOM 248 C CG . GLU A 1 59 ? -74.004 -19.037 -40.845 1.00 77.78 ? 121 GLU A CG 1 +ATOM 249 C CD . GLU A 1 59 ? -74.713 -18.044 -41.738 1.00 97.71 ? 121 GLU A CD 1 +ATOM 250 O OE1 . GLU A 1 59 ? -75.373 -17.131 -41.197 1.00 101.52 ? 121 GLU A OE1 1 +ATOM 251 O OE2 . GLU A 1 59 ? -74.608 -18.174 -42.978 1.00 104.72 ? 121 GLU A OE2 1 +ATOM 252 N N . ALA A 1 60 ? -71.298 -18.045 -38.468 1.00 71.15 ? 122 ALA A N 1 +ATOM 253 C CA . ALA A 1 60 ? -69.951 -17.670 -38.889 1.00 73.83 ? 122 ALA A CA 1 +ATOM 254 C C . ALA A 1 60 ? -68.901 -18.614 -38.315 1.00 72.34 ? 122 ALA A C 1 +ATOM 255 O O . ALA A 1 60 ? -67.979 -19.031 -39.026 1.00 67.25 ? 122 ALA A O 1 +ATOM 256 C CB . ALA A 1 60 ? -69.649 -16.230 -38.477 1.00 71.20 ? 122 ALA A CB 1 +ATOM 257 N N . LEU A 1 61 ? -69.023 -18.962 -37.030 1.00 72.15 ? 123 LEU A N 1 +ATOM 258 C CA . LEU A 1 61 ? -68.045 -19.853 -36.415 1.00 66.33 ? 123 LEU A CA 1 +ATOM 259 C C . LEU A 1 61 ? -68.030 -21.218 -37.092 1.00 67.84 ? 123 LEU A C 1 +ATOM 260 O O . LEU A 1 61 ? -66.969 -21.845 -37.197 1.00 62.14 ? 123 LEU A O 1 +ATOM 261 C CB . LEU A 1 61 ? -68.321 -19.988 -34.917 1.00 63.38 ? 123 LEU A CB 1 +ATOM 262 C CG . LEU A 1 61 ? -67.620 -18.992 -33.979 1.00 56.74 ? 123 LEU A CG 1 +ATOM 263 C CD1 . LEU A 1 61 ? -66.119 -18.941 -34.236 1.00 55.12 ? 123 LEU A CD1 1 +ATOM 264 C CD2 . LEU A 1 61 ? -68.221 -17.601 -34.067 1.00 53.12 ? 123 LEU A CD2 1 +ATOM 265 N N . ARG A 1 62 ? -69.185 -21.686 -37.575 1.00 71.92 ? 124 ARG A N 1 +ATOM 266 C CA . ARG A 1 62 ? -69.227 -22.960 -38.287 1.00 75.29 ? 124 ARG A CA 1 +ATOM 267 C C . ARG A 1 62 ? -68.477 -22.870 -39.612 1.00 72.69 ? 124 ARG A C 1 +ATOM 268 O O . ARG A 1 62 ? -67.684 -23.758 -39.948 1.00 68.78 ? 124 ARG A O 1 +ATOM 269 C CB . ARG A 1 62 ? -70.679 -23.386 -38.524 1.00 75.01 ? 124 ARG A CB 1 +ATOM 270 C CG . ARG A 1 62 ? -70.837 -24.798 -39.077 1.00 66.79 ? 124 ARG A CG 1 +ATOM 271 C CD . ARG A 1 62 ? -72.281 -25.095 -39.466 1.00 74.94 ? 124 ARG A CD 1 +ATOM 272 N NE . ARG A 1 62 ? -73.240 -24.695 -38.435 1.00 90.58 ? 124 ARG A NE 1 +ATOM 273 C CZ . ARG A 1 62 ? -74.115 -23.699 -38.559 1.00 91.91 ? 124 ARG A CZ 1 +ATOM 274 N NH1 . ARG A 1 62 ? -74.172 -22.991 -39.680 1.00 89.21 ? 124 ARG A NH1 1 +ATOM 275 N NH2 . ARG A 1 62 ? -74.943 -23.414 -37.560 1.00 86.65 ? 124 ARG A NH2 1 +ATOM 276 N N . TYR A 1 63 ? -68.720 -21.800 -40.378 1.00 69.59 ? 125 TYR A N 1 +ATOM 277 C CA . TYR A 1 63 ? -68.075 -21.635 -41.679 1.00 64.55 ? 125 TYR A CA 1 +ATOM 278 C C . TYR A 1 63 ? -66.563 -21.506 -41.543 1.00 68.07 ? 125 TYR A C 1 +ATOM 279 O O . TYR A 1 63 ? -65.809 -22.111 -42.314 1.00 67.64 ? 125 TYR A O 1 +ATOM 280 C CB . TYR A 1 63 ? -68.651 -20.417 -42.397 1.00 66.66 ? 125 TYR A CB 1 +ATOM 281 C CG . TYR A 1 63 ? -68.034 -20.160 -43.755 1.00 77.33 ? 125 TYR A CG 1 +ATOM 282 C CD1 . TYR A 1 63 ? -68.047 -21.133 -44.747 1.00 76.60 ? 125 TYR A CD1 1 +ATOM 283 C CD2 . TYR A 1 63 ? -67.419 -18.948 -44.037 1.00 78.48 ? 125 TYR A CD2 1 +ATOM 284 C CE1 . TYR A 1 63 ? -67.479 -20.895 -45.985 1.00 73.59 ? 125 TYR A CE1 1 +ATOM 285 C CE2 . TYR A 1 63 ? -66.850 -18.702 -45.270 1.00 75.38 ? 125 TYR A CE2 1 +ATOM 286 C CZ . TYR A 1 63 ? -66.882 -19.678 -46.238 1.00 78.80 ? 125 TYR A CZ 1 +ATOM 287 O OH . TYR A 1 63 ? -66.316 -19.431 -47.465 1.00 88.41 ? 125 TYR A OH 1 +ATOM 288 N N . TYR A 1 64 ? -66.098 -20.677 -40.601 1.00 69.21 ? 126 TYR A N 1 +ATOM 289 C CA . TYR A 1 64 ? -64.658 -20.561 -40.383 1.00 66.43 ? 126 TYR A CA 1 +ATOM 290 C C . TYR A 1 64 ? -64.074 -21.865 -39.856 1.00 61.54 ? 126 TYR A C 1 +ATOM 291 O O . TYR A 1 64 ? -62.899 -22.161 -40.101 1.00 54.81 ? 126 TYR A O 1 +ATOM 292 C CB . TYR A 1 64 ? -64.338 -19.402 -39.431 1.00 62.01 ? 126 TYR A CB 1 +ATOM 293 C CG . TYR A 1 64 ? -64.523 -18.029 -40.051 1.00 61.84 ? 126 TYR A CG 1 +ATOM 294 C CD1 . TYR A 1 64 ? -64.308 -17.826 -41.410 1.00 68.66 ? 126 TYR A CD1 1 +ATOM 295 C CD2 . TYR A 1 64 ? -64.934 -16.945 -39.288 1.00 60.13 ? 126 TYR A CD2 1 +ATOM 296 C CE1 . TYR A 1 64 ? -64.487 -16.583 -41.989 1.00 61.52 ? 126 TYR A CE1 1 +ATOM 297 C CE2 . TYR A 1 64 ? -65.119 -15.694 -39.861 1.00 60.90 ? 126 TYR A CE2 1 +ATOM 298 C CZ . TYR A 1 64 ? -64.892 -15.522 -41.213 1.00 61.15 ? 126 TYR A CZ 1 +ATOM 299 O OH . TYR A 1 64 ? -65.068 -14.286 -41.792 1.00 62.64 ? 126 TYR A OH 1 +ATOM 300 N N . ARG A 1 65 ? -64.872 -22.653 -39.130 1.00 64.77 ? 127 ARG A N 1 +ATOM 301 C CA . ARG A 1 65 ? -64.384 -23.937 -38.646 1.00 64.56 ? 127 ARG A CA 1 +ATOM 302 C C . ARG A 1 65 ? -64.228 -24.942 -39.780 1.00 59.22 ? 127 ARG A C 1 +ATOM 303 O O . ARG A 1 65 ? -63.312 -25.772 -39.746 1.00 57.77 ? 127 ARG A O 1 +ATOM 304 C CB . ARG A 1 65 ? -65.311 -24.473 -37.553 1.00 66.12 ? 127 ARG A CB 1 +ATOM 305 C CG . ARG A 1 65 ? -64.709 -25.613 -36.744 1.00 73.52 ? 127 ARG A CG 1 +ATOM 306 C CD . ARG A 1 65 ? -65.549 -25.947 -35.521 1.00 76.17 ? 127 ARG A CD 1 +ATOM 307 N NE . ARG A 1 65 ? -65.545 -24.869 -34.531 1.00 78.24 ? 127 ARG A NE 1 +ATOM 308 C CZ . ARG A 1 65 ? -66.552 -24.023 -34.339 1.00 75.93 ? 127 ARG A CZ 1 +ATOM 309 N NH1 . ARG A 1 65 ? -67.650 -24.127 -35.077 1.00 77.89 ? 127 ARG A NH1 1 +ATOM 310 N NH2 . ARG A 1 65 ? -66.463 -23.077 -33.409 1.00 57.73 ? 127 ARG A NH2 1 +ATOM 311 N N . ARG A 1 66 ? -65.080 -24.867 -40.805 1.00 62.30 ? 128 ARG A N 1 +ATOM 312 C CA . ARG A 1 66 ? -64.911 -25.760 -41.947 1.00 62.71 ? 128 ARG A CA 1 +ATOM 313 C C . ARG A 1 66 ? -63.675 -25.385 -42.747 1.00 57.28 ? 128 ARG A C 1 +ATOM 314 O O . ARG A 1 66 ? -62.903 -26.260 -43.153 1.00 56.41 ? 128 ARG A O 1 +ATOM 315 C CB . ARG A 1 66 ? -66.147 -25.727 -42.851 1.00 71.28 ? 128 ARG A CB 1 +ATOM 316 C CG . ARG A 1 66 ? -67.347 -26.518 -42.329 1.00 79.17 ? 128 ARG A CG 1 +ATOM 317 C CD . ARG A 1 66 ? -68.339 -26.869 -43.449 1.00 83.06 ? 128 ARG A CD 1 +ATOM 318 N NE . ARG A 1 66 ? -69.101 -25.721 -43.945 1.00 85.40 ? 128 ARG A NE 1 +ATOM 319 C CZ . ARG A 1 66 ? -70.339 -25.410 -43.561 1.00 84.78 ? 128 ARG A CZ 1 +ATOM 320 N NH1 . ARG A 1 66 ? -70.980 -26.156 -42.666 1.00 84.04 ? 128 ARG A NH1 1 +ATOM 321 N NH2 . ARG A 1 66 ? -70.944 -24.347 -44.078 1.00 71.80 ? 128 ARG A NH2 1 +ATOM 322 N N . LYS A 1 67 ? -63.467 -24.086 -42.975 1.00 61.61 ? 129 LYS A N 1 +ATOM 323 C CA . LYS A 1 67 ? -62.293 -23.644 -43.720 1.00 67.05 ? 129 LYS A CA 1 +ATOM 324 C C . LYS A 1 67 ? -60.996 -23.966 -42.987 1.00 59.53 ? 129 LYS A C 1 +ATOM 325 O O . LYS A 1 67 ? -59.953 -24.142 -43.626 1.00 58.20 ? 129 LYS A O 1 +ATOM 326 C CB . LYS A 1 67 ? -62.387 -22.149 -44.030 1.00 71.46 ? 129 LYS A CB 1 +ATOM 327 C CG . LYS A 1 67 ? -63.408 -21.808 -45.118 1.00 71.08 ? 129 LYS A CG 1 +ATOM 328 C CD . LYS A 1 67 ? -62.737 -21.213 -46.363 1.00 80.12 ? 129 LYS A CD 1 +ATOM 329 C CE . LYS A 1 67 ? -61.860 -22.239 -47.088 1.00 69.47 ? 129 LYS A CE 1 +ATOM 330 N NZ . LYS A 1 67 ? -61.143 -21.687 -48.278 1.00 77.84 ? 129 LYS A NZ 1 +ATOM 331 N N . VAL A 1 68 ? -61.029 -24.041 -41.656 1.00 58.45 ? 130 VAL A N 1 +ATOM 332 C CA . VAL A 1 68 ? -59.849 -24.500 -40.933 1.00 57.07 ? 130 VAL A CA 1 +ATOM 333 C C . VAL A 1 68 ? -59.645 -25.988 -41.171 1.00 57.42 ? 130 VAL A C 1 +ATOM 334 O O . VAL A 1 68 ? -58.515 -26.459 -41.350 1.00 56.46 ? 130 VAL A O 1 +ATOM 335 C CB . VAL A 1 68 ? -59.972 -24.178 -39.434 1.00 54.82 ? 130 VAL A CB 1 +ATOM 336 C CG1 . VAL A 1 68 ? -58.868 -24.865 -38.648 1.00 56.40 ? 130 VAL A CG1 1 +ATOM 337 C CG2 . VAL A 1 68 ? -59.926 -22.684 -39.211 1.00 54.20 ? 130 VAL A CG2 1 +ATOM 338 N N . ALA A 1 69 ? -60.740 -26.747 -41.204 1.00 60.33 ? 131 ALA A N 1 +ATOM 339 C CA . ALA A 1 69 ? -60.642 -28.168 -41.513 1.00 64.07 ? 131 ALA A CA 1 +ATOM 340 C C . ALA A 1 69 ? -60.128 -28.375 -42.931 1.00 68.96 ? 131 ALA A C 1 +ATOM 341 O O . ALA A 1 69 ? -59.212 -29.174 -43.161 1.00 66.96 ? 131 ALA A O 1 +ATOM 342 C CB . ALA A 1 69 ? -62.006 -28.837 -41.330 1.00 59.25 ? 131 ALA A CB 1 +ATOM 343 N N . ARG A 1 70 ? -60.684 -27.627 -43.893 1.00 70.81 ? 132 ARG A N 1 +ATOM 344 C CA . ARG A 1 70 ? -60.273 -27.776 -45.286 1.00 62.47 ? 132 ARG A CA 1 +ATOM 345 C C . ARG A 1 70 ? -58.837 -27.320 -45.488 1.00 61.86 ? 132 ARG A C 1 +ATOM 346 O O . ARG A 1 70 ? -58.111 -27.887 -46.310 1.00 67.74 ? 132 ARG A O 1 +ATOM 347 C CB . ARG A 1 70 ? -61.221 -27.001 -46.204 1.00 55.66 ? 132 ARG A CB 1 +ATOM 348 C CG . ARG A 1 70 ? -62.639 -27.544 -46.209 1.00 70.05 ? 132 ARG A CG 1 +ATOM 349 C CD . ARG A 1 70 ? -63.538 -26.871 -47.243 1.00 92.63 ? 132 ARG A CD 1 +ATOM 350 N NE . ARG A 1 70 ? -64.908 -27.390 -47.201 1.00 107.27 ? 132 ARG A NE 1 +ATOM 351 C CZ . ARG A 1 70 ? -65.899 -26.963 -47.981 1.00 118.99 ? 132 ARG A CZ 1 +ATOM 352 N NH1 . ARG A 1 70 ? -65.675 -26.008 -48.876 1.00 125.70 ? 132 ARG A NH1 1 +ATOM 353 N NH2 . ARG A 1 70 ? -67.113 -27.491 -47.868 1.00 105.86 ? 132 ARG A NH2 1 +ATOM 354 N N . TRP A 1 71 ? -58.414 -26.289 -44.760 1.00 60.56 ? 133 TRP A N 1 +ATOM 355 C CA . TRP A 1 71 ? -57.034 -25.846 -44.879 1.00 63.76 ? 133 TRP A CA 1 +ATOM 356 C C . TRP A 1 71 ? -56.071 -26.882 -44.315 1.00 64.17 ? 133 TRP A C 1 +ATOM 357 O O . TRP A 1 71 ? -55.022 -27.150 -44.915 1.00 67.42 ? 133 TRP A O 1 +ATOM 358 C CB . TRP A 1 71 ? -56.836 -24.505 -44.178 1.00 59.42 ? 133 TRP A CB 1 +ATOM 359 C CG . TRP A 1 71 ? -55.502 -23.898 -44.463 1.00 52.83 ? 133 TRP A CG 1 +ATOM 360 C CD1 . TRP A 1 71 ? -55.210 -22.988 -45.435 1.00 57.64 ? 133 TRP A CD1 1 +ATOM 361 C CD2 . TRP A 1 71 ? -54.270 -24.181 -43.794 1.00 51.51 ? 133 TRP A CD2 1 +ATOM 362 N NE1 . TRP A 1 71 ? -53.874 -22.672 -45.400 1.00 59.89 ? 133 TRP A NE1 1 +ATOM 363 C CE2 . TRP A 1 71 ? -53.274 -23.394 -44.402 1.00 54.08 ? 133 TRP A CE2 1 +ATOM 364 C CE3 . TRP A 1 71 ? -53.914 -25.016 -42.734 1.00 58.55 ? 133 TRP A CE3 1 +ATOM 365 C CZ2 . TRP A 1 71 ? -51.947 -23.418 -43.986 1.00 50.18 ? 133 TRP A CZ2 1 +ATOM 366 C CZ3 . TRP A 1 71 ? -52.597 -25.040 -42.325 1.00 63.74 ? 133 TRP A CZ3 1 +ATOM 367 C CH2 . TRP A 1 71 ? -51.628 -24.245 -42.949 1.00 53.52 ? 133 TRP A CH2 1 +ATOM 368 N N . ASN A 1 72 ? -56.409 -27.488 -43.173 1.00 63.05 ? 134 ASN A N 1 +ATOM 369 C CA . ASN A 1 72 ? -55.449 -28.383 -42.531 1.00 71.73 ? 134 ASN A CA 1 +ATOM 370 C C . ASN A 1 72 ? -55.058 -29.548 -43.418 1.00 79.79 ? 134 ASN A C 1 +ATOM 371 O O . ASN A 1 72 ? -53.914 -30.012 -43.357 1.00 80.93 ? 134 ASN A O 1 +ATOM 372 C CB . ASN A 1 72 ? -55.979 -28.884 -41.193 1.00 74.55 ? 134 ASN A CB 1 +ATOM 373 C CG . ASN A 1 72 ? -55.485 -28.046 -40.056 1.00 73.04 ? 134 ASN A CG 1 +ATOM 374 O OD1 . ASN A 1 72 ? -56.233 -27.666 -39.158 1.00 75.57 ? 134 ASN A OD1 1 +ATOM 375 N ND2 . ASN A 1 72 ? -54.190 -27.743 -40.091 1.00 66.31 ? 134 ASN A ND2 1 +ATOM 376 N N . ARG A 1 73 ? -55.974 -30.034 -44.243 1.00 80.78 ? 135 ARG A N 1 +ATOM 377 C CA . ARG A 1 73 ? -55.593 -31.057 -45.199 1.00 77.26 ? 135 ARG A CA 1 +ATOM 378 C C . ARG A 1 73 ? -54.702 -30.450 -46.278 1.00 76.42 ? 135 ARG A C 1 +ATOM 379 O O . ARG A 1 73 ? -53.482 -30.485 -46.103 1.00 80.00 ? 135 ARG A O 1 +ATOM 380 C CB . ARG A 1 73 ? -56.854 -31.761 -45.701 1.00 73.52 ? 135 ARG A CB 1 +ATOM 381 C CG . ARG A 1 73 ? -57.040 -33.100 -44.969 1.00 75.58 ? 135 ARG A CG 1 +ATOM 382 C CD . ARG A 1 73 ? -58.472 -33.595 -44.882 1.00 72.06 ? 135 ARG A CD 1 +ATOM 383 N NE . ARG A 1 73 ? -59.178 -33.628 -46.150 1.00 72.65 ? 135 ARG A NE 1 +ATOM 384 C CZ . ARG A 1 73 ? -60.135 -32.761 -46.442 1.00 74.51 ? 135 ARG A CZ 1 +ATOM 385 N NH1 . ARG A 1 73 ? -60.456 -31.845 -45.541 1.00 71.48 ? 135 ARG A NH1 1 +ATOM 386 N NH2 . ARG A 1 73 ? -60.774 -32.811 -47.603 1.00 80.70 ? 135 ARG A NH2 1 +ATOM 387 N N . ARG A 1 74 ? -55.263 -29.833 -47.329 1.00 77.38 ? 136 ARG A N 1 +ATOM 388 C CA . ARG A 1 74 ? -54.508 -29.359 -48.501 1.00 85.37 ? 136 ARG A CA 1 +ATOM 389 C C . ARG A 1 74 ? -52.998 -29.211 -48.295 1.00 92.09 ? 136 ARG A C 1 +ATOM 390 O O . ARG A 1 74 ? -52.198 -29.652 -49.130 1.00 92.61 ? 136 ARG A O 1 +ATOM 391 C CB . ARG A 1 74 ? -55.026 -27.991 -48.956 1.00 77.10 ? 136 ARG A CB 1 +ATOM 392 C CG . ARG A 1 74 ? -56.342 -27.964 -49.686 1.00 76.40 ? 136 ARG A CG 1 +ATOM 393 C CD . ARG A 1 74 ? -56.452 -26.637 -50.416 1.00 75.29 ? 136 ARG A CD 1 +ATOM 394 N NE . ARG A 1 74 ? -56.514 -25.492 -49.511 1.00 84.87 ? 136 ARG A NE 1 +ATOM 395 C CZ . ARG A 1 74 ? -57.551 -24.663 -49.448 1.00 94.64 ? 136 ARG A CZ 1 +ATOM 396 N NH1 . ARG A 1 74 ? -58.595 -24.859 -50.244 1.00 98.16 ? 136 ARG A NH1 1 +ATOM 397 N NH2 . ARG A 1 74 ? -57.549 -23.638 -48.602 1.00 81.77 ? 136 ARG A NH2 1 +ATOM 398 N N . HIS A 1 75 ? -52.604 -28.631 -47.154 1.00 86.85 ? 137 HIS A N 1 +ATOM 399 C CA . HIS A 1 75 ? -51.190 -28.472 -46.839 1.00 85.66 ? 137 HIS A CA 1 +ATOM 400 C C . HIS A 1 75 ? -50.575 -29.753 -46.286 1.00 88.25 ? 137 HIS A C 1 +ATOM 401 O O . HIS A 1 75 ? -49.399 -30.024 -46.554 1.00 99.78 ? 137 HIS A O 1 +ATOM 402 C CB . HIS A 1 75 ? -50.997 -27.290 -45.888 1.00 78.90 ? 137 HIS A CB 1 +ATOM 403 C CG . HIS A 1 75 ? -50.976 -25.964 -46.589 1.00 79.09 ? 137 HIS A CG 1 +ATOM 404 N ND1 . HIS A 1 75 ? -50.024 -24.999 -46.337 1.00 74.31 ? 137 HIS A ND1 1 +ATOM 405 C CD2 . HIS A 1 75 ? -51.774 -25.460 -47.563 1.00 68.61 ? 137 HIS A CD2 1 +ATOM 406 C CE1 . HIS A 1 75 ? -50.245 -23.954 -47.115 1.00 63.68 ? 137 HIS A CE1 1 +ATOM 407 N NE2 . HIS A 1 75 ? -51.301 -24.208 -47.868 1.00 64.26 ? 137 HIS A NE2 1 +ATOM 408 N N . LYS A 1 76 ? -51.326 -30.542 -45.514 1.00 85.18 ? 138 LYS A N 1 +ATOM 409 C CA . LYS A 1 76 ? -50.816 -31.845 -45.088 1.00 87.70 ? 138 LYS A CA 1 +ATOM 410 C C . LYS A 1 76 ? -50.508 -32.737 -46.287 1.00 100.67 ? 138 LYS A C 1 +ATOM 411 O O . LYS A 1 76 ? -49.467 -33.407 -46.320 1.00 104.82 ? 138 LYS A O 1 +ATOM 412 C CB . LYS A 1 76 ? -51.819 -32.532 -44.166 1.00 79.76 ? 138 LYS A CB 1 +ATOM 413 C CG . LYS A 1 76 ? -51.557 -34.012 -43.982 1.00 85.33 ? 138 LYS A CG 1 +ATOM 414 C CD . LYS A 1 76 ? -52.554 -34.610 -43.021 1.00 94.02 ? 138 LYS A CD 1 +ATOM 415 C CE . LYS A 1 76 ? -52.308 -34.101 -41.611 1.00 99.13 ? 138 LYS A CE 1 +ATOM 416 N NZ . LYS A 1 76 ? -50.946 -34.455 -41.109 1.00 84.65 ? 138 LYS A NZ 1 +ATOM 417 N N . MET A 1 77 ? -51.401 -32.767 -47.273 1.00 101.02 ? 139 MET A N 1 +ATOM 418 C CA . MET A 1 77 ? -51.144 -33.484 -48.521 1.00 94.48 ? 139 MET A CA 1 +ATOM 419 C C . MET A 1 77 ? -50.029 -32.805 -49.307 1.00 85.70 ? 139 MET A C 1 +ATOM 420 O O . MET A 1 77 ? -49.241 -33.469 -49.980 1.00 88.29 ? 139 MET A O 1 +ATOM 421 C CB . MET A 1 77 ? -52.410 -33.578 -49.377 1.00 94.34 ? 139 MET A CB 1 +ATOM 422 C CG . MET A 1 77 ? -53.511 -34.426 -48.764 1.00 107.82 ? 139 MET A CG 1 +ATOM 423 S SD . MET A 1 77 ? -54.805 -34.865 -49.944 1.00 154.98 ? 139 MET A SD 1 +ATOM 424 C CE . MET A 1 77 ? -54.042 -36.230 -50.816 1.00 94.08 ? 139 MET A CE 1 +ATOM 425 N N . ASP A 1 88 ? -45.820 -31.093 -35.722 1.00 105.34 ? 150 ASP A N 1 +ATOM 426 C CA . ASP A 1 88 ? -46.708 -30.009 -35.313 1.00 112.25 ? 150 ASP A CA 1 +ATOM 427 C C . ASP A 1 88 ? -48.179 -30.412 -35.437 1.00 120.45 ? 150 ASP A C 1 +ATOM 428 O O . ASP A 1 88 ? -48.581 -30.997 -36.448 1.00 109.22 ? 150 ASP A O 1 +ATOM 429 C CB . ASP A 1 88 ? -46.437 -28.754 -36.148 1.00 115.55 ? 150 ASP A CB 1 +ATOM 430 C CG . ASP A 1 88 ? -45.033 -28.211 -35.950 1.00 119.31 ? 150 ASP A CG 1 +ATOM 431 O OD1 . ASP A 1 88 ? -44.476 -28.388 -34.845 1.00 110.75 ? 150 ASP A OD1 1 +ATOM 432 O OD2 . ASP A 1 88 ? -44.487 -27.607 -36.900 1.00 117.37 ? 150 ASP A OD2 1 +ATOM 433 N N . PRO A 1 89 ? -48.978 -30.092 -34.418 1.00 126.31 ? 151 PRO A N 1 +ATOM 434 C CA . PRO A 1 89 ? -50.414 -30.421 -34.456 1.00 116.07 ? 151 PRO A CA 1 +ATOM 435 C C . PRO A 1 89 ? -51.145 -29.578 -35.488 1.00 108.89 ? 151 PRO A C 1 +ATOM 436 O O . PRO A 1 89 ? -50.618 -28.558 -35.960 1.00 96.81 ? 151 PRO A O 1 +ATOM 437 C CB . PRO A 1 89 ? -50.886 -30.097 -33.029 1.00 102.67 ? 151 PRO A CB 1 +ATOM 438 C CG . PRO A 1 89 ? -49.934 -29.057 -32.548 1.00 103.79 ? 151 PRO A CG 1 +ATOM 439 C CD . PRO A 1 89 ? -48.604 -29.374 -33.185 1.00 113.15 ? 151 PRO A CD 1 +ATOM 440 N N . PRO A 1 90 ? -52.367 -29.961 -35.857 1.00 108.22 ? 152 PRO A N 1 +ATOM 441 C CA . PRO A 1 90 ? -53.120 -29.186 -36.851 1.00 90.38 ? 152 PRO A CA 1 +ATOM 442 C C . PRO A 1 90 ? -53.632 -27.868 -36.287 1.00 80.74 ? 152 PRO A C 1 +ATOM 443 O O . PRO A 1 90 ? -53.572 -27.586 -35.088 1.00 78.18 ? 152 PRO A O 1 +ATOM 444 C CB . PRO A 1 90 ? -54.277 -30.117 -37.229 1.00 89.64 ? 152 PRO A CB 1 +ATOM 445 C CG . PRO A 1 90 ? -54.452 -31.002 -36.044 1.00 93.33 ? 152 PRO A CG 1 +ATOM 446 C CD . PRO A 1 90 ? -53.072 -31.201 -35.478 1.00 102.82 ? 152 PRO A CD 1 +ATOM 447 N N . LEU A 1 91 ? -54.137 -27.046 -37.202 1.00 79.52 ? 153 LEU A N 1 +ATOM 448 C CA . LEU A 1 91 ? -54.658 -25.736 -36.846 1.00 78.24 ? 153 LEU A CA 1 +ATOM 449 C C . LEU A 1 91 ? -55.868 -25.878 -35.928 1.00 71.75 ? 153 LEU A C 1 +ATOM 450 O O . LEU A 1 91 ? -56.635 -26.841 -36.012 1.00 64.95 ? 153 LEU A O 1 +ATOM 451 C CB . LEU A 1 91 ? -55.032 -24.954 -38.110 1.00 71.92 ? 153 LEU A CB 1 +ATOM 452 C CG . LEU A 1 91 ? -54.525 -23.517 -38.298 1.00 65.85 ? 153 LEU A CG 1 +ATOM 453 C CD1 . LEU A 1 91 ? -54.997 -22.632 -37.156 1.00 69.63 ? 153 LEU A CD1 1 +ATOM 454 C CD2 . LEU A 1 91 ? -53.004 -23.455 -38.444 1.00 61.49 ? 153 LEU A CD2 1 +ATOM 455 N N . GLN A 1 92 ? -56.005 -24.924 -35.013 1.00 69.86 ? 154 GLN A N 1 +ATOM 456 C CA . GLN A 1 92 ? -57.145 -24.846 -34.114 1.00 70.51 ? 154 GLN A CA 1 +ATOM 457 C C . GLN A 1 92 ? -57.827 -23.500 -34.304 1.00 66.82 ? 154 GLN A C 1 +ATOM 458 O O . GLN A 1 92 ? -57.177 -22.451 -34.227 1.00 63.90 ? 154 GLN A O 1 +ATOM 459 C CB . GLN A 1 92 ? -56.713 -25.039 -32.656 1.00 83.45 ? 154 GLN A CB 1 +ATOM 460 C CG . GLN A 1 92 ? -57.871 -25.321 -31.712 1.00 90.64 ? 154 GLN A CG 1 +ATOM 461 C CD . GLN A 1 92 ? -58.267 -26.785 -31.708 1.00 97.44 ? 154 GLN A CD 1 +ATOM 462 O OE1 . GLN A 1 92 ? -57.796 -27.569 -32.537 1.00 100.07 ? 154 GLN A OE1 1 +ATOM 463 N NE2 . GLN A 1 92 ? -59.155 -27.159 -30.790 1.00 84.16 ? 154 GLN A NE2 1 +ATOM 464 N N . LEU A 1 93 ? -59.132 -23.532 -34.553 1.00 58.39 ? 155 LEU A N 1 +ATOM 465 C CA . LEU A 1 93 ? -59.916 -22.318 -34.748 1.00 56.56 ? 155 LEU A CA 1 +ATOM 466 C C . LEU A 1 93 ? -60.446 -21.867 -33.389 1.00 62.91 ? 155 LEU A C 1 +ATOM 467 O O . LEU A 1 93 ? -61.385 -22.466 -32.854 1.00 63.35 ? 155 LEU A O 1 +ATOM 468 C CB . LEU A 1 93 ? -61.050 -22.578 -35.740 1.00 54.71 ? 155 LEU A CB 1 +ATOM 469 C CG . LEU A 1 93 ? -61.876 -21.417 -36.304 1.00 52.16 ? 155 LEU A CG 1 +ATOM 470 C CD1 . LEU A 1 93 ? -63.109 -21.145 -35.450 1.00 55.22 ? 155 LEU A CD1 1 +ATOM 471 C CD2 . LEU A 1 93 ? -61.027 -20.167 -36.449 1.00 51.09 ? 155 LEU A CD2 1 +ATOM 472 N N . ARG A 1 94 ? -59.846 -20.813 -32.833 1.00 59.48 ? 156 ARG A N 1 +ATOM 473 C CA . ARG A 1 94 ? -60.212 -20.292 -31.521 1.00 61.71 ? 156 ARG A CA 1 +ATOM 474 C C . ARG A 1 94 ? -61.043 -19.024 -31.655 1.00 57.96 ? 156 ARG A C 1 +ATOM 475 O O . ARG A 1 94 ? -60.689 -18.125 -32.424 1.00 61.25 ? 156 ARG A O 1 +ATOM 476 C CB . ARG A 1 94 ? -58.966 -19.998 -30.680 1.00 71.80 ? 156 ARG A CB 1 +ATOM 477 C CG . ARG A 1 94 ? -58.332 -21.228 -30.048 1.00 92.42 ? 156 ARG A CG 1 +ATOM 478 C CD . ARG A 1 94 ? -57.317 -20.843 -28.977 1.00 93.73 ? 156 ARG A CD 1 +ATOM 479 N NE . ARG A 1 94 ? -56.117 -20.236 -29.546 1.00 102.24 ? 156 ARG A NE 1 +ATOM 480 C CZ . ARG A 1 94 ? -55.033 -20.919 -29.904 1.00 114.68 ? 156 ARG A CZ 1 +ATOM 481 N NH1 . ARG A 1 94 ? -54.993 -22.239 -29.754 1.00 108.22 ? 156 ARG A NH1 1 +ATOM 482 N NH2 . ARG A 1 94 ? -53.986 -20.282 -30.412 1.00 114.13 ? 156 ARG A NH2 1 +ATOM 483 N N . LEU A 1 95 ? -62.137 -18.950 -30.889 1.00 53.10 ? 157 LEU A N 1 +ATOM 484 C CA . LEU A 1 95 ? -62.967 -17.747 -30.870 1.00 52.11 ? 157 LEU A CA 1 +ATOM 485 C C . LEU A 1 95 ? -62.182 -16.538 -30.378 1.00 59.64 ? 157 LEU A C 1 +ATOM 486 O O . LEU A 1 95 ? -62.484 -15.399 -30.754 1.00 57.20 ? 157 LEU A O 1 +ATOM 487 C CB . LEU A 1 95 ? -64.197 -17.974 -29.990 1.00 50.46 ? 157 LEU A CB 1 +ATOM 488 C CG . LEU A 1 95 ? -65.567 -17.482 -30.466 1.00 47.01 ? 157 LEU A CG 1 +ATOM 489 C CD1 . LEU A 1 95 ? -66.649 -17.866 -29.469 1.00 38.00 ? 157 LEU A CD1 1 +ATOM 490 C CD2 . LEU A 1 95 ? -65.575 -15.984 -30.680 1.00 53.76 ? 157 LEU A CD2 1 +ATOM 491 N N . GLU A 1 96 ? -61.173 -16.764 -29.538 1.00 67.74 ? 158 GLU A N 1 +ATOM 492 C CA . GLU A 1 96 ? -60.361 -15.678 -29.004 1.00 67.85 ? 158 GLU A CA 1 +ATOM 493 C C . GLU A 1 96 ? -59.412 -15.082 -30.037 1.00 69.39 ? 158 GLU A C 1 +ATOM 494 O O . GLU A 1 96 ? -58.617 -14.207 -29.677 1.00 79.66 ? 158 GLU A O 1 +ATOM 495 C CB . GLU A 1 96 ? -59.554 -16.163 -27.794 1.00 71.94 ? 158 GLU A CB 1 +ATOM 496 C CG . GLU A 1 96 ? -60.345 -16.975 -26.770 1.00 76.16 ? 158 GLU A CG 1 +ATOM 497 C CD . GLU A 1 96 ? -60.339 -18.466 -27.059 1.00 74.61 ? 158 GLU A CD 1 +ATOM 498 O OE1 . GLU A 1 96 ? -61.358 -18.976 -27.571 1.00 70.21 ? 158 GLU A OE1 1 +ATOM 499 O OE2 . GLU A 1 96 ? -59.314 -19.126 -26.780 1.00 77.45 ? 158 GLU A OE2 1 +ATOM 500 N N . ALA A 1 97 ? -59.449 -15.534 -31.289 1.00 62.81 ? 159 ALA A N 1 +ATOM 501 C CA . ALA A 1 97 ? -58.561 -14.982 -32.299 1.00 55.00 ? 159 ALA A CA 1 +ATOM 502 C C . ALA A 1 97 ? -58.975 -13.559 -32.652 1.00 51.21 ? 159 ALA A C 1 +ATOM 503 O O . ALA A 1 97 ? -60.147 -13.181 -32.562 1.00 46.16 ? 159 ALA A O 1 +ATOM 504 C CB . ALA A 1 97 ? -58.558 -15.853 -33.553 1.00 52.04 ? 159 ALA A CB 1 +ATOM 505 N N . SER A 1 98 ? -57.989 -12.768 -33.071 1.00 47.89 ? 160 SER A N 1 +ATOM 506 C CA . SER A 1 98 ? -58.241 -11.355 -33.310 1.00 45.30 ? 160 SER A CA 1 +ATOM 507 C C . SER A 1 98 ? -59.206 -11.158 -34.471 1.00 45.20 ? 160 SER A C 1 +ATOM 508 O O . SER A 1 98 ? -60.244 -10.504 -34.320 1.00 48.35 ? 160 SER A O 1 +ATOM 509 C CB . SER A 1 98 ? -56.920 -10.637 -33.569 1.00 44.05 ? 160 SER A CB 1 +ATOM 510 O OG . SER A 1 98 ? -56.024 -10.866 -32.498 1.00 38.00 ? 160 SER A OG 1 +ATOM 511 N N . TRP A 1 99 ? -58.899 -11.747 -35.628 1.00 38.76 ? 161 TRP A N 1 +ATOM 512 C CA . TRP A 1 99 ? -59.749 -11.554 -36.797 1.00 41.41 ? 161 TRP A CA 1 +ATOM 513 C C . TRP A 1 99 ? -61.154 -12.094 -36.571 1.00 41.10 ? 161 TRP A C 1 +ATOM 514 O O . TRP A 1 99 ? -62.115 -11.585 -37.158 1.00 38.00 ? 161 TRP A O 1 +ATOM 515 C CB . TRP A 1 99 ? -59.118 -12.216 -38.016 1.00 47.05 ? 161 TRP A CB 1 +ATOM 516 C CG . TRP A 1 99 ? -59.016 -13.692 -37.892 1.00 50.57 ? 161 TRP A CG 1 +ATOM 517 C CD1 . TRP A 1 99 ? -58.054 -14.391 -37.225 1.00 49.96 ? 161 TRP A CD1 1 +ATOM 518 C CD2 . TRP A 1 99 ? -59.906 -14.667 -38.456 1.00 52.43 ? 161 TRP A CD2 1 +ATOM 519 N NE1 . TRP A 1 99 ? -58.289 -15.741 -37.341 1.00 53.79 ? 161 TRP A NE1 1 +ATOM 520 C CE2 . TRP A 1 99 ? -59.419 -15.935 -38.092 1.00 52.20 ? 161 TRP A CE2 1 +ATOM 521 C CE3 . TRP A 1 99 ? -61.066 -14.588 -39.233 1.00 51.83 ? 161 TRP A CE3 1 +ATOM 522 C CZ2 . TRP A 1 99 ? -60.053 -17.114 -38.475 1.00 53.15 ? 161 TRP A CZ2 1 +ATOM 523 C CZ3 . TRP A 1 99 ? -61.692 -15.762 -39.612 1.00 48.44 ? 161 TRP A CZ3 1 +ATOM 524 C CH2 . TRP A 1 99 ? -61.187 -17.004 -39.233 1.00 50.27 ? 161 TRP A CH2 1 +ATOM 525 N N . VAL A 1 100 ? -61.294 -13.128 -35.745 1.00 38.00 ? 162 VAL A N 1 +ATOM 526 C CA . VAL A 1 100 ? -62.617 -13.667 -35.457 1.00 38.00 ? 162 VAL A CA 1 +ATOM 527 C C . VAL A 1 100 ? -63.463 -12.646 -34.705 1.00 40.97 ? 162 VAL A C 1 +ATOM 528 O O . VAL A 1 100 ? -64.610 -12.374 -35.076 1.00 39.76 ? 162 VAL A O 1 +ATOM 529 C CB . VAL A 1 100 ? -62.498 -14.987 -34.678 1.00 44.31 ? 162 VAL A CB 1 +ATOM 530 C CG1 . VAL A 1 100 ? -63.874 -15.574 -34.427 1.00 46.77 ? 162 VAL A CG1 1 +ATOM 531 C CG2 . VAL A 1 100 ? -61.641 -15.962 -35.452 1.00 47.73 ? 162 VAL A CG2 1 +ATOM 532 N N . GLN A 1 101 ? -62.917 -12.079 -33.625 1.00 50.09 ? 163 GLN A N 1 +ATOM 533 C CA . GLN A 1 101 ? -63.664 -11.077 -32.868 1.00 50.70 ? 163 GLN A CA 1 +ATOM 534 C C . GLN A 1 101 ? -63.865 -9.798 -33.672 1.00 43.34 ? 163 GLN A C 1 +ATOM 535 O O . GLN A 1 101 ? -64.907 -9.141 -33.544 1.00 38.00 ? 163 GLN A O 1 +ATOM 536 C CB . GLN A 1 101 ? -62.957 -10.785 -31.542 1.00 49.45 ? 163 GLN A CB 1 +ATOM 537 C CG . GLN A 1 101 ? -63.917 -10.618 -30.369 1.00 52.41 ? 163 GLN A CG 1 +ATOM 538 C CD . GLN A 1 101 ? -64.701 -11.885 -30.065 1.00 52.49 ? 163 GLN A CD 1 +ATOM 539 O OE1 . GLN A 1 101 ? -64.270 -12.994 -30.385 1.00 51.52 ? 163 GLN A OE1 1 +ATOM 540 N NE2 . GLN A 1 101 ? -65.874 -11.720 -29.466 1.00 49.73 ? 163 GLN A NE2 1 +ATOM 541 N N . PHE A 1 102 ? -62.899 -9.452 -34.526 1.00 43.41 ? 164 PHE A N 1 +ATOM 542 C CA . PHE A 1 102 ? -63.056 -8.298 -35.404 1.00 39.72 ? 164 PHE A CA 1 +ATOM 543 C C . PHE A 1 102 ? -64.224 -8.491 -36.361 1.00 40.70 ? 164 PHE A C 1 +ATOM 544 O O . PHE A 1 102 ? -65.026 -7.572 -36.563 1.00 41.08 ? 164 PHE A O 1 +ATOM 545 C CB . PHE A 1 102 ? -61.755 -8.050 -36.171 1.00 38.00 ? 164 PHE A CB 1 +ATOM 546 C CG . PHE A 1 102 ? -61.915 -7.149 -37.364 1.00 40.21 ? 164 PHE A CG 1 +ATOM 547 C CD1 . PHE A 1 102 ? -62.413 -5.867 -37.218 1.00 44.16 ? 164 PHE A CD1 1 +ATOM 548 C CD2 . PHE A 1 102 ? -61.534 -7.572 -38.629 1.00 39.97 ? 164 PHE A CD2 1 +ATOM 549 C CE1 . PHE A 1 102 ? -62.558 -5.036 -38.310 1.00 41.92 ? 164 PHE A CE1 1 +ATOM 550 C CE2 . PHE A 1 102 ? -61.672 -6.741 -39.725 1.00 38.00 ? 164 PHE A CE2 1 +ATOM 551 C CZ . PHE A 1 102 ? -62.184 -5.473 -39.564 1.00 38.00 ? 164 PHE A CZ 1 +ATOM 552 N N . HIS A 1 103 ? -64.349 -9.688 -36.941 1.00 40.83 ? 165 HIS A N 1 +ATOM 553 C CA . HIS A 1 103 ? -65.449 -9.949 -37.863 1.00 39.77 ? 165 HIS A CA 1 +ATOM 554 C C . HIS A 1 103 ? -66.780 -9.951 -37.130 1.00 41.29 ? 165 HIS A C 1 +ATOM 555 O O . HIS A 1 103 ? -67.773 -9.413 -37.631 1.00 45.34 ? 165 HIS A O 1 +ATOM 556 C CB . HIS A 1 103 ? -65.247 -11.275 -38.590 1.00 39.09 ? 165 HIS A CB 1 +ATOM 557 C CG . HIS A 1 103 ? -64.143 -11.255 -39.596 1.00 44.94 ? 165 HIS A CG 1 +ATOM 558 N ND1 . HIS A 1 103 ? -63.915 -12.299 -40.466 1.00 52.19 ? 165 HIS A ND1 1 +ATOM 559 C CD2 . HIS A 1 103 ? -63.192 -10.330 -39.864 1.00 47.64 ? 165 HIS A CD2 1 +ATOM 560 C CE1 . HIS A 1 103 ? -62.879 -12.013 -41.234 1.00 50.63 ? 165 HIS A CE1 1 +ATOM 561 N NE2 . HIS A 1 103 ? -62.419 -10.825 -40.887 1.00 45.74 ? 165 HIS A NE2 1 +ATOM 562 N N . LEU A 1 104 ? -66.831 -10.581 -35.957 1.00 41.16 ? 166 LEU A N 1 +ATOM 563 C CA . LEU A 1 104 ? -68.066 -10.578 -35.189 1.00 45.39 ? 166 LEU A CA 1 +ATOM 564 C C . LEU A 1 104 ? -68.380 -9.214 -34.593 1.00 46.21 ? 166 LEU A C 1 +ATOM 565 O O . LEU A 1 104 ? -69.534 -8.978 -34.214 1.00 47.34 ? 166 LEU A O 1 +ATOM 566 C CB . LEU A 1 104 ? -67.989 -11.628 -34.083 1.00 47.29 ? 166 LEU A CB 1 +ATOM 567 C CG . LEU A 1 104 ? -67.772 -13.065 -34.553 1.00 42.44 ? 166 LEU A CG 1 +ATOM 568 C CD1 . LEU A 1 104 ? -67.002 -13.847 -33.508 1.00 38.58 ? 166 LEU A CD1 1 +ATOM 569 C CD2 . LEU A 1 104 ? -69.118 -13.722 -34.845 1.00 49.21 ? 166 LEU A CD2 1 +ATOM 570 N N . GLY A 1 105 ? -67.409 -8.300 -34.563 1.00 46.99 ? 167 GLY A N 1 +ATOM 571 C CA . GLY A 1 105 ? -67.570 -6.964 -34.027 1.00 55.43 ? 167 GLY A CA 1 +ATOM 572 C C . GLY A 1 105 ? -67.949 -5.897 -35.028 1.00 47.00 ? 167 GLY A C 1 +ATOM 573 O O . GLY A 1 105 ? -68.019 -4.714 -34.676 1.00 38.33 ? 167 GLY A O 1 +ATOM 574 N N . ILE A 1 106 ? -68.191 -6.286 -36.276 1.00 48.06 ? 168 ILE A N 1 +ATOM 575 C CA . ILE A 1 106 ? -68.639 -5.358 -37.307 1.00 45.88 ? 168 ILE A CA 1 +ATOM 576 C C . ILE A 1 106 ? -70.146 -5.177 -37.180 1.00 47.53 ? 168 ILE A C 1 +ATOM 577 O O . ILE A 1 106 ? -70.921 -6.116 -37.400 1.00 44.74 ? 168 ILE A O 1 +ATOM 578 C CB . ILE A 1 106 ? -68.250 -5.855 -38.706 1.00 46.04 ? 168 ILE A CB 1 +ATOM 579 C CG1 . ILE A 1 106 ? -66.755 -6.164 -38.755 1.00 42.11 ? 168 ILE A CG1 1 +ATOM 580 C CG2 . ILE A 1 106 ? -68.578 -4.814 -39.753 1.00 51.20 ? 168 ILE A CG2 1 +ATOM 581 C CD1 . ILE A 1 106 ? -66.260 -6.536 -40.122 1.00 38.00 ? 168 ILE A CD1 1 +ATOM 582 N N . ASN A 1 107 ? -70.557 -3.963 -36.844 1.00 52.24 ? 169 ASN A N 1 +ATOM 583 C CA . ASN A 1 107 ? -71.941 -3.597 -36.607 1.00 52.94 ? 169 ASN A CA 1 +ATOM 584 C C . ASN A 1 107 ? -72.377 -2.574 -37.648 1.00 51.48 ? 169 ASN A C 1 +ATOM 585 O O . ASN A 1 107 ? -71.587 -2.125 -38.482 1.00 49.26 ? 169 ASN A O 1 +ATOM 586 C CB . ASN A 1 107 ? -72.118 -3.036 -35.191 1.00 55.34 ? 169 ASN A CB 1 +ATOM 587 C CG . ASN A 1 107 ? -71.085 -1.966 -34.842 1.00 62.66 ? 169 ASN A CG 1 +ATOM 588 O OD1 . ASN A 1 107 ? -70.075 -1.800 -35.532 1.00 61.63 ? 169 ASN A OD1 1 +ATOM 589 N ND2 . ASN A 1 107 ? -71.339 -1.234 -33.761 1.00 60.30 ? 169 ASN A ND2 1 +ATOM 590 N N . ARG A 1 108 ? -73.650 -2.184 -37.571 1.00 56.37 ? 170 ARG A N 1 +ATOM 591 C CA . ARG A 1 108 ? -74.188 -1.179 -38.476 1.00 56.11 ? 170 ARG A CA 1 +ATOM 592 C C . ARG A 1 108 ? -73.514 0.177 -38.313 1.00 54.31 ? 170 ARG A C 1 +ATOM 593 O O . ARG A 1 108 ? -73.637 1.024 -39.206 1.00 52.21 ? 170 ARG A O 1 +ATOM 594 C CB . ARG A 1 108 ? -75.696 -1.049 -38.246 1.00 58.70 ? 170 ARG A CB 1 +ATOM 595 C CG . ARG A 1 108 ? -76.436 -0.278 -39.317 1.00 55.99 ? 170 ARG A CG 1 +ATOM 596 C CD . ARG A 1 108 ? -77.931 -0.324 -39.079 1.00 60.21 ? 170 ARG A CD 1 +ATOM 597 N NE . ARG A 1 108 ? -78.447 -1.686 -39.134 1.00 64.34 ? 170 ARG A NE 1 +ATOM 598 C CZ . ARG A 1 108 ? -78.942 -2.242 -40.233 1.00 65.81 ? 170 ARG A CZ 1 +ATOM 599 N NH1 . ARG A 1 108 ? -78.983 -1.547 -41.361 1.00 64.31 ? 170 ARG A NH1 1 +ATOM 600 N NH2 . ARG A 1 108 ? -79.394 -3.486 -40.209 1.00 71.08 ? 170 ARG A NH2 1 +ATOM 601 N N . HIS A 1 109 ? -72.783 0.391 -37.221 1.00 57.45 ? 171 HIS A N 1 +ATOM 602 C CA . HIS A 1 109 ? -72.153 1.670 -36.932 1.00 58.49 ? 171 HIS A CA 1 +ATOM 603 C C . HIS A 1 109 ? -70.724 1.759 -37.442 1.00 56.27 ? 171 HIS A C 1 +ATOM 604 O O . HIS A 1 109 ? -70.100 2.818 -37.324 1.00 59.24 ? 171 HIS A O 1 +ATOM 605 C CB . HIS A 1 109 ? -72.182 1.938 -35.427 1.00 62.60 ? 171 HIS A CB 1 +ATOM 606 C CG . HIS A 1 109 ? -73.503 2.441 -34.939 1.00 69.52 ? 171 HIS A CG 1 +ATOM 607 N ND1 . HIS A 1 109 ? -73.773 2.656 -33.605 1.00 80.70 ? 171 HIS A ND1 1 +ATOM 608 C CD2 . HIS A 1 109 ? -74.633 2.766 -35.612 1.00 64.42 ? 171 HIS A CD2 1 +ATOM 609 C CE1 . HIS A 1 109 ? -75.013 3.096 -33.478 1.00 88.70 ? 171 HIS A CE1 1 +ATOM 610 N NE2 . HIS A 1 109 ? -75.556 3.171 -34.680 1.00 82.69 ? 171 HIS A NE2 1 +ATOM 611 N N . GLY A 1 110 ? -70.194 0.694 -38.001 1.00 51.68 ? 172 GLY A N 1 +ATOM 612 C CA . GLY A 1 110 ? -68.886 0.766 -38.614 1.00 54.22 ? 172 GLY A CA 1 +ATOM 613 C C . GLY A 1 110 ? -68.179 -0.568 -38.559 1.00 49.61 ? 172 GLY A C 1 +ATOM 614 O O . GLY A 1 110 ? -68.697 -1.560 -38.054 1.00 46.13 ? 172 GLY A O 1 +ATOM 615 N N . LEU A 1 111 ? -66.951 -0.552 -39.077 1.00 44.28 ? 173 LEU A N 1 +ATOM 616 C CA . LEU A 1 111 ? -66.152 -1.766 -39.149 1.00 42.79 ? 173 LEU A CA 1 +ATOM 617 C C . LEU A 1 111 ? -65.680 -2.198 -37.768 1.00 44.48 ? 173 LEU A C 1 +ATOM 618 O O . LEU A 1 111 ? -65.660 -3.395 -37.456 1.00 45.91 ? 173 LEU A O 1 +ATOM 619 C CB . LEU A 1 111 ? -64.970 -1.546 -40.090 1.00 41.16 ? 173 LEU A CB 1 +ATOM 620 C CG . LEU A 1 111 ? -64.965 -2.430 -41.337 1.00 43.29 ? 173 LEU A CG 1 +ATOM 621 C CD1 . LEU A 1 111 ? -66.286 -2.324 -42.097 1.00 38.00 ? 173 LEU A CD1 1 +ATOM 622 C CD2 . LEU A 1 111 ? -63.776 -2.092 -42.237 1.00 40.44 ? 173 LEU A CD2 1 +ATOM 623 N N . TYR A 1 112 ? -65.269 -1.249 -36.938 1.00 43.64 ? 174 TYR A N 1 +ATOM 624 C CA . TYR A 1 112 ? -64.765 -1.555 -35.611 1.00 47.55 ? 174 TYR A CA 1 +ATOM 625 C C . TYR A 1 112 ? -65.424 -0.642 -34.580 1.00 49.18 ? 174 TYR A C 1 +ATOM 626 O O . TYR A 1 112 ? -66.245 0.222 -34.907 1.00 42.76 ? 174 TYR A O 1 +ATOM 627 C CB . TYR A 1 112 ? -63.235 -1.463 -35.579 1.00 45.72 ? 174 TYR A CB 1 +ATOM 628 C CG . TYR A 1 112 ? -62.655 -0.220 -36.210 1.00 46.18 ? 174 TYR A CG 1 +ATOM 629 C CD1 . TYR A 1 112 ? -62.574 -0.093 -37.590 1.00 53.22 ? 174 TYR A CD1 1 +ATOM 630 C CD2 . TYR A 1 112 ? -62.162 0.813 -35.429 1.00 47.79 ? 174 TYR A CD2 1 +ATOM 631 C CE1 . TYR A 1 112 ? -62.040 1.036 -38.177 1.00 52.16 ? 174 TYR A CE1 1 +ATOM 632 C CE2 . TYR A 1 112 ? -61.616 1.946 -36.010 1.00 52.77 ? 174 TYR A CE2 1 +ATOM 633 C CZ . TYR A 1 112 ? -61.564 2.051 -37.386 1.00 46.65 ? 174 TYR A CZ 1 +ATOM 634 O OH . TYR A 1 112 ? -61.033 3.169 -37.979 1.00 42.93 ? 174 TYR A OH 1 +ATOM 635 N N . SER A 1 113 ? -65.080 -0.871 -33.315 1.00 53.67 ? 175 SER A N 1 +ATOM 636 C CA . SER A 1 113 ? -65.633 -0.123 -32.199 1.00 44.77 ? 175 SER A CA 1 +ATOM 637 C C . SER A 1 113 ? -64.765 1.084 -31.883 1.00 45.89 ? 175 SER A C 1 +ATOM 638 O O . SER A 1 113 ? -63.559 1.106 -32.145 1.00 44.22 ? 175 SER A O 1 +ATOM 639 C CB . SER A 1 113 ? -65.748 -1.001 -30.954 1.00 47.60 ? 175 SER A CB 1 +ATOM 640 O OG . SER A 1 113 ? -66.186 -2.307 -31.280 1.00 62.41 ? 175 SER A OG 1 +ATOM 641 N N . ARG A 1 114 ? -65.394 2.082 -31.274 1.00 45.50 ? 176 ARG A N 1 +ATOM 642 C CA . ARG A 1 114 ? -64.683 3.289 -30.885 1.00 43.12 ? 176 ARG A CA 1 +ATOM 643 C C . ARG A 1 114 ? -63.748 2.961 -29.731 1.00 40.19 ? 176 ARG A C 1 +ATOM 644 O O . ARG A 1 114 ? -64.193 2.454 -28.695 1.00 42.69 ? 176 ARG A O 1 +ATOM 645 C CB . ARG A 1 114 ? -65.677 4.381 -30.504 1.00 38.00 ? 176 ARG A CB 1 +ATOM 646 C CG . ARG A 1 114 ? -65.024 5.687 -30.130 1.00 44.17 ? 176 ARG A CG 1 +ATOM 647 C CD . ARG A 1 114 ? -65.885 6.849 -30.561 1.00 45.97 ? 176 ARG A CD 1 +ATOM 648 N NE . ARG A 1 114 ? -67.221 6.783 -29.984 1.00 49.52 ? 176 ARG A NE 1 +ATOM 649 C CZ . ARG A 1 114 ? -68.235 7.551 -30.367 1.00 59.94 ? 176 ARG A CZ 1 +ATOM 650 N NH1 . ARG A 1 114 ? -68.072 8.442 -31.338 1.00 56.40 ? 176 ARG A NH1 1 +ATOM 651 N NH2 . ARG A 1 114 ? -69.417 7.425 -29.782 1.00 67.33 ? 176 ARG A NH2 1 +ATOM 652 N N . SER A 1 115 ? -62.455 3.218 -29.921 1.00 38.00 ? 177 SER A N 1 +ATOM 653 C CA . SER A 1 115 ? -61.421 2.840 -28.959 1.00 47.93 ? 177 SER A CA 1 +ATOM 654 C C . SER A 1 115 ? -61.580 1.377 -28.555 1.00 50.31 ? 177 SER A C 1 +ATOM 655 O O . SER A 1 115 ? -61.796 1.038 -27.390 1.00 44.63 ? 177 SER A O 1 +ATOM 656 C CB . SER A 1 115 ? -61.431 3.753 -27.731 1.00 48.38 ? 177 SER A CB 1 +ATOM 657 O OG . SER A 1 115 ? -60.948 5.044 -28.053 1.00 57.28 ? 177 SER A OG 1 +ATOM 658 N N . SER A 1 116 ? -61.484 0.507 -29.563 1.00 53.71 ? 178 SER A N 1 +ATOM 659 C CA . SER A 1 116 ? -61.712 -0.918 -29.368 1.00 49.83 ? 178 SER A CA 1 +ATOM 660 C C . SER A 1 116 ? -60.415 -1.607 -28.969 1.00 46.35 ? 178 SER A C 1 +ATOM 661 O O . SER A 1 116 ? -59.404 -1.466 -29.666 1.00 43.99 ? 178 SER A O 1 +ATOM 662 C CB . SER A 1 116 ? -62.260 -1.556 -30.639 1.00 46.90 ? 178 SER A CB 1 +ATOM 663 O OG . SER A 1 116 ? -62.282 -2.970 -30.540 1.00 50.29 ? 178 SER A OG 1 +ATOM 664 N N . PRO A 1 117 ? -60.408 -2.355 -27.867 1.00 46.81 ? 179 PRO A N 1 +ATOM 665 C CA . PRO A 1 117 ? -59.216 -3.147 -27.534 1.00 49.27 ? 179 PRO A CA 1 +ATOM 666 C C . PRO A 1 117 ? -59.004 -4.317 -28.479 1.00 49.27 ? 179 PRO A C 1 +ATOM 667 O O . PRO A 1 117 ? -57.887 -4.847 -28.548 1.00 43.10 ? 179 PRO A O 1 +ATOM 668 C CB . PRO A 1 117 ? -59.500 -3.616 -26.102 1.00 52.31 ? 179 PRO A CB 1 +ATOM 669 C CG . PRO A 1 117 ? -61.001 -3.647 -26.015 1.00 46.86 ? 179 PRO A CG 1 +ATOM 670 C CD . PRO A 1 117 ? -61.491 -2.522 -26.882 1.00 43.90 ? 179 PRO A CD 1 +ATOM 671 N N . VAL A 1 118 ? -60.051 -4.730 -29.200 1.00 51.52 ? 180 VAL A N 1 +ATOM 672 C CA . VAL A 1 118 ? -59.936 -5.806 -30.180 1.00 44.52 ? 180 VAL A CA 1 +ATOM 673 C C . VAL A 1 118 ? -59.024 -5.385 -31.322 1.00 41.13 ? 180 VAL A C 1 +ATOM 674 O O . VAL A 1 118 ? -58.110 -6.116 -31.722 1.00 39.89 ? 180 VAL A O 1 +ATOM 675 C CB . VAL A 1 118 ? -61.335 -6.183 -30.702 1.00 38.00 ? 180 VAL A CB 1 +ATOM 676 C CG1 . VAL A 1 118 ? -61.236 -7.172 -31.856 1.00 40.82 ? 180 VAL A CG1 1 +ATOM 677 C CG2 . VAL A 1 118 ? -62.201 -6.721 -29.576 1.00 38.18 ? 180 VAL A CG2 1 +ATOM 678 N N . VAL A 1 119 ? -59.253 -4.186 -31.849 1.00 39.65 ? 181 VAL A N 1 +ATOM 679 C CA . VAL A 1 119 ? -58.466 -3.697 -32.969 1.00 38.09 ? 181 VAL A CA 1 +ATOM 680 C C . VAL A 1 119 ? -57.020 -3.485 -32.548 1.00 38.00 ? 181 VAL A C 1 +ATOM 681 O O . VAL A 1 119 ? -56.090 -3.733 -33.321 1.00 38.06 ? 181 VAL A O 1 +ATOM 682 C CB . VAL A 1 119 ? -59.108 -2.415 -33.517 1.00 38.00 ? 181 VAL A CB 1 +ATOM 683 C CG1 . VAL A 1 119 ? -58.464 -2.010 -34.815 1.00 38.00 ? 181 VAL A CG1 1 +ATOM 684 C CG2 . VAL A 1 119 ? -60.596 -2.631 -33.685 1.00 38.00 ? 181 VAL A CG2 1 +ATOM 685 N N . SER A 1 120 ? -56.807 -3.047 -31.308 1.00 38.00 ? 182 SER A N 1 +ATOM 686 C CA . SER A 1 120 ? -55.450 -2.865 -30.809 1.00 40.49 ? 182 SER A CA 1 +ATOM 687 C C . SER A 1 120 ? -54.688 -4.184 -30.806 1.00 43.56 ? 182 SER A C 1 +ATOM 688 O O . SER A 1 120 ? -53.495 -4.223 -31.130 1.00 45.85 ? 182 SER A O 1 +ATOM 689 C CB . SER A 1 120 ? -55.502 -2.271 -29.403 1.00 50.23 ? 182 SER A CB 1 +ATOM 690 O OG . SER A 1 120 ? -56.118 -0.996 -29.423 1.00 50.75 ? 182 SER A OG 1 +ATOM 691 N N . LYS A 1 121 ? -55.362 -5.273 -30.425 1.00 44.72 ? 183 LYS A N 1 +ATOM 692 C CA . LYS A 1 121 ? -54.758 -6.599 -30.503 1.00 43.11 ? 183 LYS A CA 1 +ATOM 693 C C . LYS A 1 121 ? -54.648 -7.063 -31.946 1.00 40.33 ? 183 LYS A C 1 +ATOM 694 O O . LYS A 1 121 ? -53.648 -7.677 -32.335 1.00 42.63 ? 183 LYS A O 1 +ATOM 695 C CB . LYS A 1 121 ? -55.580 -7.593 -29.682 1.00 48.45 ? 183 LYS A CB 1 +ATOM 696 C CG . LYS A 1 121 ? -55.032 -9.016 -29.642 1.00 46.26 ? 183 LYS A CG 1 +ATOM 697 C CD . LYS A 1 121 ? -53.682 -9.085 -28.945 1.00 43.46 ? 183 LYS A CD 1 +ATOM 698 C CE . LYS A 1 121 ? -53.364 -10.503 -28.500 1.00 38.00 ? 183 LYS A CE 1 +ATOM 699 N NZ . LYS A 1 121 ? -53.533 -11.492 -29.592 1.00 38.00 ? 183 LYS A NZ 1 +ATOM 700 N N . LEU A 1 122 ? -55.666 -6.764 -32.753 1.00 40.14 ? 184 LEU A N 1 +ATOM 701 C CA . LEU A 1 122 ? -55.641 -7.148 -34.158 1.00 41.12 ? 184 LEU A CA 1 +ATOM 702 C C . LEU A 1 122 ? -54.436 -6.539 -34.863 1.00 38.57 ? 184 LEU A C 1 +ATOM 703 O O . LEU A 1 122 ? -53.703 -7.233 -35.577 1.00 38.00 ? 184 LEU A O 1 +ATOM 704 C CB . LEU A 1 122 ? -56.955 -6.721 -34.821 1.00 38.00 ? 184 LEU A CB 1 +ATOM 705 C CG . LEU A 1 122 ? -57.151 -6.981 -36.309 1.00 38.00 ? 184 LEU A CG 1 +ATOM 706 C CD1 . LEU A 1 122 ? -56.917 -8.437 -36.589 1.00 38.00 ? 184 LEU A CD1 1 +ATOM 707 C CD2 . LEU A 1 122 ? -58.556 -6.603 -36.704 1.00 38.00 ? 184 LEU A CD2 1 +ATOM 708 N N . LEU A 1 123 ? -54.192 -5.246 -34.636 1.00 40.01 ? 185 LEU A N 1 +ATOM 709 C CA . LEU A 1 123 ? -53.029 -4.591 -35.223 1.00 38.82 ? 185 LEU A CA 1 +ATOM 710 C C . LEU A 1 123 ? -51.730 -5.217 -34.731 1.00 38.97 ? 185 LEU A C 1 +ATOM 711 O O . LEU A 1 123 ? -50.793 -5.410 -35.514 1.00 40.82 ? 185 LEU A O 1 +ATOM 712 C CB . LEU A 1 123 ? -53.057 -3.092 -34.916 1.00 41.62 ? 185 LEU A CB 1 +ATOM 713 C CG . LEU A 1 123 ? -53.922 -2.191 -35.804 1.00 38.00 ? 185 LEU A CG 1 +ATOM 714 C CD1 . LEU A 1 123 ? -54.955 -1.465 -34.983 1.00 38.00 ? 185 LEU A CD1 1 +ATOM 715 C CD2 . LEU A 1 123 ? -53.068 -1.173 -36.530 1.00 48.32 ? 185 LEU A CD2 1 +ATOM 716 N N . GLN A 1 124 ? -51.646 -5.529 -33.435 1.00 40.03 ? 186 GLN A N 1 +ATOM 717 C CA . GLN A 1 124 ? -50.426 -6.131 -32.904 1.00 44.40 ? 186 GLN A CA 1 +ATOM 718 C C . GLN A 1 124 ? -50.216 -7.540 -33.445 1.00 41.94 ? 186 GLN A C 1 +ATOM 719 O O . GLN A 1 124 ? -49.071 -7.981 -33.600 1.00 38.00 ? 186 GLN A O 1 +ATOM 720 C CB . GLN A 1 124 ? -50.466 -6.145 -31.374 1.00 46.03 ? 186 GLN A CB 1 +ATOM 721 C CG . GLN A 1 124 ? -50.281 -4.780 -30.722 1.00 52.75 ? 186 GLN A CG 1 +ATOM 722 C CD . GLN A 1 124 ? -48.963 -4.115 -31.093 1.00 55.63 ? 186 GLN A CD 1 +ATOM 723 O OE1 . GLN A 1 124 ? -48.944 -3.028 -31.677 1.00 57.32 ? 186 GLN A OE1 1 +ATOM 724 N NE2 . GLN A 1 124 ? -47.855 -4.765 -30.753 1.00 53.28 ? 186 GLN A NE2 1 +ATOM 725 N N . ASP A 1 125 ? -51.304 -8.253 -33.750 1.00 42.55 ? 187 ASP A N 1 +ATOM 726 C CA . ASP A 1 125 ? -51.172 -9.605 -34.282 1.00 42.58 ? 187 ASP A CA 1 +ATOM 727 C C . ASP A 1 125 ? -50.628 -9.582 -35.702 1.00 39.32 ? 187 ASP A C 1 +ATOM 728 O O . ASP A 1 125 ? -49.678 -10.304 -36.026 1.00 38.00 ? 187 ASP A O 1 +ATOM 729 C CB . ASP A 1 125 ? -52.519 -10.331 -34.245 1.00 43.67 ? 187 ASP A CB 1 +ATOM 730 C CG . ASP A 1 125 ? -52.896 -10.788 -32.857 1.00 43.36 ? 187 ASP A CG 1 +ATOM 731 O OD1 . ASP A 1 125 ? -52.153 -10.460 -31.910 1.00 46.99 ? 187 ASP A OD1 1 +ATOM 732 O OD2 . ASP A 1 125 ? -53.910 -11.507 -32.717 1.00 44.31 ? 187 ASP A OD2 1 +ATOM 733 N N . MET A 1 126 ? -51.195 -8.731 -36.556 1.00 38.00 ? 188 MET A N 1 +ATOM 734 C CA . MET A 1 126 ? -50.724 -8.650 -37.929 1.00 38.00 ? 188 MET A CA 1 +ATOM 735 C C . MET A 1 126 ? -49.272 -8.199 -38.008 1.00 38.00 ? 188 MET A C 1 +ATOM 736 O O . MET A 1 126 ? -48.615 -8.446 -39.025 1.00 38.00 ? 188 MET A O 1 +ATOM 737 C CB . MET A 1 126 ? -51.628 -7.708 -38.724 1.00 38.00 ? 188 MET A CB 1 +ATOM 738 C CG . MET A 1 126 ? -53.102 -8.071 -38.637 1.00 38.00 ? 188 MET A CG 1 +ATOM 739 S SD . MET A 1 126 ? -54.128 -7.299 -39.903 1.00 38.00 ? 188 MET A SD 1 +ATOM 740 C CE . MET A 1 126 ? -54.334 -5.654 -39.252 1.00 38.00 ? 188 MET A CE 1 +ATOM 741 N N . ARG A 1 127 ? -48.743 -7.585 -36.949 1.00 38.00 ? 189 ARG A N 1 +ATOM 742 C CA . ARG A 1 127 ? -47.355 -7.147 -36.958 1.00 38.00 ? 189 ARG A CA 1 +ATOM 743 C C . ARG A 1 127 ? -46.388 -8.251 -36.562 1.00 40.74 ? 189 ARG A C 1 +ATOM 744 O O . ARG A 1 127 ? -45.250 -8.266 -37.044 1.00 38.00 ? 189 ARG A O 1 +ATOM 745 C CB . ARG A 1 127 ? -47.153 -5.955 -36.012 1.00 43.07 ? 189 ARG A CB 1 +ATOM 746 C CG . ARG A 1 127 ? -45.833 -5.203 -36.241 1.00 46.91 ? 189 ARG A CG 1 +ATOM 747 C CD . ARG A 1 127 ? -45.259 -4.569 -34.973 1.00 51.32 ? 189 ARG A CD 1 +ATOM 748 N NE . ARG A 1 127 ? -46.271 -3.867 -34.188 1.00 64.00 ? 189 ARG A NE 1 +ATOM 749 C CZ . ARG A 1 127 ? -46.726 -2.650 -34.469 1.00 69.27 ? 189 ARG A CZ 1 +ATOM 750 N NH1 . ARG A 1 127 ? -46.264 -2.003 -35.528 1.00 69.84 ? 189 ARG A NH1 1 +ATOM 751 N NH2 . ARG A 1 127 ? -47.651 -2.084 -33.700 1.00 63.08 ? 189 ARG A NH2 1 +ATOM 752 N N . HIS A 1 128 ? -46.820 -9.191 -35.717 1.00 47.86 ? 190 HIS A N 1 +ATOM 753 C CA . HIS A 1 128 ? -45.917 -10.169 -35.121 1.00 50.28 ? 190 HIS A CA 1 +ATOM 754 C C . HIS A 1 128 ? -46.206 -11.616 -35.484 1.00 44.55 ? 190 HIS A C 1 +ATOM 755 O O . HIS A 1 128 ? -45.262 -12.407 -35.570 1.00 40.14 ? 190 HIS A O 1 +ATOM 756 C CB . HIS A 1 128 ? -45.939 -10.054 -33.588 1.00 47.44 ? 190 HIS A CB 1 +ATOM 757 C CG . HIS A 1 128 ? -45.500 -8.722 -33.075 1.00 46.21 ? 190 HIS A CG 1 +ATOM 758 N ND1 . HIS A 1 128 ? -44.182 -8.437 -32.791 1.00 51.21 ? 190 HIS A ND1 1 +ATOM 759 C CD2 . HIS A 1 128 ? -46.201 -7.603 -32.778 1.00 45.70 ? 190 HIS A CD2 1 +ATOM 760 C CE1 . HIS A 1 128 ? -44.088 -7.195 -32.353 1.00 60.92 ? 190 HIS A CE1 1 +ATOM 761 N NE2 . HIS A 1 128 ? -45.299 -6.668 -32.332 1.00 63.70 ? 190 HIS A NE2 1 +ATOM 762 N N . PHE A 1 129 ? -47.465 -11.984 -35.698 1.00 44.23 ? 191 PHE A N 1 +ATOM 763 C CA . PHE A 1 129 ? -47.794 -13.375 -35.961 1.00 47.10 ? 191 PHE A CA 1 +ATOM 764 C C . PHE A 1 129 ? -47.054 -13.859 -37.205 1.00 51.80 ? 191 PHE A C 1 +ATOM 765 O O . PHE A 1 129 ? -46.945 -13.119 -38.192 1.00 55.81 ? 191 PHE A O 1 +ATOM 766 C CB . PHE A 1 129 ? -49.303 -13.537 -36.147 1.00 44.10 ? 191 PHE A CB 1 +ATOM 767 C CG . PHE A 1 129 ? -50.062 -13.716 -34.861 1.00 45.19 ? 191 PHE A CG 1 +ATOM 768 C CD1 . PHE A 1 129 ? -49.852 -12.863 -33.791 1.00 44.59 ? 191 PHE A CD1 1 +ATOM 769 C CD2 . PHE A 1 129 ? -51.030 -14.699 -34.744 1.00 43.08 ? 191 PHE A CD2 1 +ATOM 770 C CE1 . PHE A 1 129 ? -50.558 -13.015 -32.616 1.00 38.00 ? 191 PHE A CE1 1 +ATOM 771 C CE2 . PHE A 1 129 ? -51.748 -14.848 -33.572 1.00 43.57 ? 191 PHE A CE2 1 +ATOM 772 C CZ . PHE A 1 129 ? -51.513 -14.003 -32.508 1.00 38.00 ? 191 PHE A CZ 1 +ATOM 773 N N . PRO A 1 130 ? -46.532 -15.081 -37.195 1.00 50.20 ? 192 PRO A N 1 +ATOM 774 C CA . PRO A 1 130 ? -45.825 -15.588 -38.373 1.00 54.62 ? 192 PRO A CA 1 +ATOM 775 C C . PRO A 1 130 ? -46.800 -15.959 -39.481 1.00 54.96 ? 192 PRO A C 1 +ATOM 776 O O . PRO A 1 130 ? -47.977 -16.252 -39.250 1.00 49.70 ? 192 PRO A O 1 +ATOM 777 C CB . PRO A 1 130 ? -45.089 -16.819 -37.837 1.00 50.93 ? 192 PRO A CB 1 +ATOM 778 C CG . PRO A 1 130 ? -45.970 -17.302 -36.735 1.00 46.33 ? 192 PRO A CG 1 +ATOM 779 C CD . PRO A 1 130 ? -46.561 -16.068 -36.102 1.00 45.16 ? 192 PRO A CD 1 +ATOM 780 N N . THR A 1 131 ? -46.285 -15.937 -40.706 1.00 48.72 ? 193 THR A N 1 +ATOM 781 C CA . THR A 1 131 ? -47.078 -16.279 -41.876 1.00 47.94 ? 193 THR A CA 1 +ATOM 782 C C . THR A 1 131 ? -47.028 -17.780 -42.126 1.00 44.81 ? 193 THR A C 1 +ATOM 783 O O . THR A 1 131 ? -46.010 -18.433 -41.877 1.00 42.35 ? 193 THR A O 1 +ATOM 784 C CB . THR A 1 131 ? -46.585 -15.514 -43.106 1.00 46.02 ? 193 THR A CB 1 +ATOM 785 O OG1 . THR A 1 131 ? -45.174 -15.706 -43.257 1.00 45.26 ? 193 THR A OG1 1 +ATOM 786 C CG2 . THR A 1 131 ? -46.887 -14.032 -42.969 1.00 46.79 ? 193 THR A CG2 1 +ATOM 787 N N . ILE A 1 132 ? -48.154 -18.328 -42.575 1.00 44.98 ? 194 ILE A N 1 +ATOM 788 C CA . ILE A 1 132 ? -48.263 -19.752 -42.874 1.00 48.07 ? 194 ILE A CA 1 +ATOM 789 C C . ILE A 1 132 ? -48.606 -20.031 -44.328 1.00 48.42 ? 194 ILE A C 1 +ATOM 790 O O . ILE A 1 132 ? -48.605 -21.204 -44.732 1.00 52.40 ? 194 ILE A O 1 +ATOM 791 C CB . ILE A 1 132 ? -49.298 -20.441 -41.960 1.00 44.87 ? 194 ILE A CB 1 +ATOM 792 C CG1 . ILE A 1 132 ? -50.714 -19.957 -42.294 1.00 44.13 ? 194 ILE A CG1 1 +ATOM 793 C CG2 . ILE A 1 132 ? -48.969 -20.194 -40.505 1.00 43.79 ? 194 ILE A CG2 1 +ATOM 794 C CD1 . ILE A 1 132 ? -51.785 -20.580 -41.430 1.00 45.74 ? 194 ILE A CD1 1 +ATOM 795 N N . SER A 1 133 ? -48.891 -19.009 -45.126 1.00 45.25 ? 195 SER A N 1 +ATOM 796 C CA . SER A 1 133 ? -49.417 -19.196 -46.467 1.00 39.12 ? 195 SER A CA 1 +ATOM 797 C C . SER A 1 133 ? -49.385 -17.858 -47.184 1.00 42.67 ? 195 SER A C 1 +ATOM 798 O O . SER A 1 133 ? -49.521 -16.808 -46.553 1.00 51.49 ? 195 SER A O 1 +ATOM 799 C CB . SER A 1 133 ? -50.848 -19.747 -46.405 1.00 44.49 ? 195 SER A CB 1 +ATOM 800 O OG . SER A 1 133 ? -51.606 -19.405 -47.549 1.00 44.15 ? 195 SER A OG 1 +ATOM 801 N N . ALA A 1 134 ? -49.218 -17.905 -48.505 1.00 45.68 ? 196 ALA A N 1 +ATOM 802 C CA . ALA A 1 134 ? -49.246 -16.703 -49.330 1.00 40.75 ? 196 ALA A CA 1 +ATOM 803 C C . ALA A 1 134 ? -49.827 -17.059 -50.690 1.00 38.00 ? 196 ALA A C 1 +ATOM 804 O O . ALA A 1 134 ? -49.443 -18.071 -51.281 1.00 39.90 ? 196 ALA A O 1 +ATOM 805 C CB . ALA A 1 134 ? -47.842 -16.097 -49.481 1.00 38.00 ? 196 ALA A CB 1 +ATOM 806 N N . ASP A 1 135 ? -50.757 -16.239 -51.178 1.00 38.00 ? 197 ASP A N 1 +ATOM 807 C CA . ASP A 1 135 ? -51.370 -16.487 -52.478 1.00 42.30 ? 197 ASP A CA 1 +ATOM 808 C C . ASP A 1 135 ? -51.406 -15.211 -53.315 1.00 47.81 ? 197 ASP A C 1 +ATOM 809 O O . ASP A 1 135 ? -50.819 -14.192 -52.936 1.00 52.61 ? 197 ASP A O 1 +ATOM 810 C CB . ASP A 1 135 ? -52.784 -17.055 -52.299 1.00 48.24 ? 197 ASP A CB 1 +ATOM 811 C CG . ASP A 1 135 ? -53.261 -17.863 -53.501 1.00 49.20 ? 197 ASP A CG 1 +ATOM 812 O OD1 . ASP A 1 135 ? -52.851 -17.559 -54.637 1.00 50.76 ? 197 ASP A OD1 1 +ATOM 813 O OD2 . ASP A 1 135 ? -54.052 -18.809 -53.307 1.00 54.58 ? 197 ASP A OD2 1 +ATOM 814 N N . TYR A 1 136 ? -52.097 -15.256 -54.452 1.00 47.14 ? 198 TYR A N 1 +ATOM 815 C CA . TYR A 1 136 ? -52.195 -14.121 -55.360 1.00 49.31 ? 198 TYR A CA 1 +ATOM 816 C C . TYR A 1 136 ? -53.461 -13.305 -55.157 1.00 50.40 ? 198 TYR A C 1 +ATOM 817 O O . TYR A 1 136 ? -53.626 -12.277 -55.821 1.00 60.71 ? 198 TYR A O 1 +ATOM 818 C CB . TYR A 1 136 ? -52.123 -14.605 -56.813 1.00 50.63 ? 198 TYR A CB 1 +ATOM 819 C CG . TYR A 1 136 ? -50.789 -14.384 -57.496 1.00 42.33 ? 198 TYR A CG 1 +ATOM 820 C CD1 . TYR A 1 136 ? -50.137 -13.166 -57.407 1.00 48.63 ? 198 TYR A CD1 1 +ATOM 821 C CD2 . TYR A 1 136 ? -50.188 -15.393 -58.232 1.00 45.11 ? 198 TYR A CD2 1 +ATOM 822 C CE1 . TYR A 1 136 ? -48.927 -12.956 -58.035 1.00 54.55 ? 198 TYR A CE1 1 +ATOM 823 C CE2 . TYR A 1 136 ? -48.974 -15.197 -58.856 1.00 48.61 ? 198 TYR A CE2 1 +ATOM 824 C CZ . TYR A 1 136 ? -48.347 -13.973 -58.756 1.00 54.69 ? 198 TYR A CZ 1 +ATOM 825 O OH . TYR A 1 136 ? -47.136 -13.751 -59.378 1.00 58.83 ? 198 TYR A OH 1 +ATOM 826 N N . SER A 1 137 ? -54.347 -13.736 -54.259 1.00 46.26 ? 199 SER A N 1 +ATOM 827 C CA . SER A 1 137 ? -55.636 -13.093 -54.016 1.00 57.07 ? 199 SER A CA 1 +ATOM 828 C C . SER A 1 137 ? -56.577 -13.211 -55.204 1.00 55.30 ? 199 SER A C 1 +ATOM 829 O O . SER A 1 137 ? -56.150 -13.475 -56.331 1.00 56.71 ? 199 SER A O 1 +ATOM 830 C CB . SER A 1 137 ? -55.461 -11.609 -53.676 1.00 59.81 ? 199 SER A CB 1 +ATOM 831 O OG . SER A 1 137 ? -55.217 -10.855 -54.856 1.00 52.12 ? 199 SER A OG 1 +ATOM 832 N N . GLN A 1 138 ? -57.860 -12.968 -54.964 1.00 59.07 ? 200 GLN A N 1 +ATOM 833 C CA . GLN A 1 138 ? -58.818 -12.869 -56.051 1.00 63.99 ? 200 GLN A CA 1 +ATOM 834 C C . GLN A 1 138 ? -58.600 -11.548 -56.772 1.00 73.16 ? 200 GLN A C 1 +ATOM 835 O O . GLN A 1 138 ? -57.534 -10.938 -56.634 1.00 72.48 ? 200 GLN A O 1 +ATOM 836 C CB . GLN A 1 138 ? -60.244 -12.972 -55.522 1.00 67.72 ? 200 GLN A CB 1 +ATOM 837 C CG . GLN A 1 138 ? -61.153 -13.790 -56.399 1.00 62.99 ? 200 GLN A CG 1 +ATOM 838 C CD . GLN A 1 138 ? -61.139 -15.262 -56.035 1.00 66.18 ? 200 GLN A CD 1 +ATOM 839 O OE1 . GLN A 1 138 ? -62.050 -16.000 -56.397 1.00 78.45 ? 200 GLN A OE1 1 +ATOM 840 N NE2 . GLN A 1 138 ? -60.110 -15.694 -55.311 1.00 52.31 ? 200 GLN A NE2 1 +ATOM 841 N N . ASP A 1 139 ? -59.586 -11.108 -57.558 1.00 75.98 ? 201 ASP A N 1 +ATOM 842 C CA . ASP A 1 139 ? -59.523 -9.843 -58.291 1.00 83.12 ? 201 ASP A CA 1 +ATOM 843 C C . ASP A 1 139 ? -58.412 -9.880 -59.342 1.00 75.75 ? 201 ASP A C 1 +ATOM 844 O O . ASP A 1 139 ? -58.614 -9.443 -60.480 1.00 75.13 ? 201 ASP A O 1 +ATOM 845 C CB . ASP A 1 139 ? -59.377 -8.668 -57.306 1.00 82.70 ? 201 ASP A CB 1 +ATOM 846 C CG . ASP A 1 139 ? -58.094 -7.878 -57.496 1.00 76.91 ? 201 ASP A CG 1 +ATOM 847 O OD1 . ASP A 1 139 ? -58.046 -7.033 -58.415 1.00 77.36 ? 201 ASP A OD1 1 +ATOM 848 O OD2 . ASP A 1 139 ? -57.145 -8.088 -56.710 1.00 69.09 ? 201 ASP A OD2 1 +ATOM 849 N N . GLU A 1 140 ? -57.241 -10.398 -58.974 1.00 71.66 ? 202 GLU A N 1 +ATOM 850 C CA . GLU A 1 140 ? -56.345 -11.048 -59.918 1.00 63.49 ? 202 GLU A CA 1 +ATOM 851 C C . GLU A 1 140 ? -56.818 -12.497 -60.036 1.00 65.89 ? 202 GLU A C 1 +ATOM 852 O O . GLU A 1 140 ? -57.976 -12.795 -59.731 1.00 70.55 ? 202 GLU A O 1 +ATOM 853 C CB . GLU A 1 140 ? -54.888 -10.920 -59.451 1.00 60.17 ? 202 GLU A CB 1 +ATOM 854 C CG . GLU A 1 140 ? -53.842 -11.248 -60.522 1.00 61.43 ? 202 GLU A CG 1 +ATOM 855 C CD . GLU A 1 140 ? -53.091 -12.537 -60.233 1.00 57.41 ? 202 GLU A CD 1 +ATOM 856 O OE1 . GLU A 1 140 ? -52.616 -12.702 -59.097 1.00 49.89 ? 202 GLU A OE1 1 +ATOM 857 O OE2 . GLU A 1 140 ? -52.996 -13.397 -61.133 1.00 55.12 ? 202 GLU A OE2 1 +ATOM 858 N N . LYS A 1 141 ? -55.954 -13.405 -60.492 1.00 65.98 ? 203 LYS A N 1 +ATOM 859 C CA . LYS A 1 141 ? -56.252 -14.833 -60.521 1.00 73.07 ? 203 LYS A CA 1 +ATOM 860 C C . LYS A 1 141 ? -57.438 -15.130 -61.432 1.00 70.28 ? 203 LYS A C 1 +ATOM 861 O O . LYS A 1 141 ? -57.343 -15.977 -62.325 1.00 72.00 ? 203 LYS A O 1 +ATOM 862 C CB . LYS A 1 141 ? -56.514 -15.343 -59.099 1.00 74.23 ? 203 LYS A CB 1 +ATOM 863 C CG . LYS A 1 141 ? -56.081 -16.773 -58.827 1.00 68.60 ? 203 LYS A CG 1 +ATOM 864 C CD . LYS A 1 141 ? -55.898 -16.978 -57.327 1.00 70.67 ? 203 LYS A CD 1 +ATOM 865 C CE . LYS A 1 141 ? -55.890 -18.441 -56.929 1.00 64.06 ? 203 LYS A CE 1 +ATOM 866 N NZ . LYS A 1 141 ? -55.553 -18.586 -55.484 1.00 55.05 ? 203 LYS A NZ 1 +ATOM 867 N N . ALA A 1 142 ? -58.557 -14.435 -61.215 1.00 74.60 ? 204 ALA A N 1 +ATOM 868 C CA . ALA A 1 142 ? -59.703 -14.532 -62.108 1.00 67.01 ? 204 ALA A CA 1 +ATOM 869 C C . ALA A 1 142 ? -59.466 -13.841 -63.442 1.00 63.18 ? 204 ALA A C 1 +ATOM 870 O O . ALA A 1 142 ? -60.319 -13.946 -64.330 1.00 56.17 ? 204 ALA A O 1 +ATOM 871 C CB . ALA A 1 142 ? -60.947 -13.944 -61.433 1.00 66.07 ? 204 ALA A CB 1 +ATOM 872 N N . LEU A 1 143 ? -58.337 -13.145 -63.606 1.00 68.75 ? 205 LEU A N 1 +ATOM 873 C CA . LEU A 1 143 ? -57.979 -12.586 -64.906 1.00 57.71 ? 205 LEU A CA 1 +ATOM 874 C C . LEU A 1 143 ? -57.527 -13.651 -65.895 1.00 52.66 ? 205 LEU A C 1 +ATOM 875 O O . LEU A 1 143 ? -57.539 -13.394 -67.104 1.00 55.07 ? 205 LEU A O 1 +ATOM 876 C CB . LEU A 1 143 ? -56.872 -11.541 -64.752 1.00 51.50 ? 205 LEU A CB 1 +ATOM 877 C CG . LEU A 1 143 ? -57.241 -10.213 -64.092 1.00 56.24 ? 205 LEU A CG 1 +ATOM 878 C CD1 . LEU A 1 143 ? -56.086 -9.230 -64.209 1.00 63.57 ? 205 LEU A CD1 1 +ATOM 879 C CD2 . LEU A 1 143 ? -58.515 -9.634 -64.693 1.00 54.75 ? 205 LEU A CD2 1 +ATOM 880 N N . LEU A 1 144 ? -57.125 -14.826 -65.407 1.00 50.12 ? 206 LEU A N 1 +ATOM 881 C CA . LEU A 1 144 ? -56.697 -15.950 -66.233 1.00 45.99 ? 206 LEU A CA 1 +ATOM 882 C C . LEU A 1 144 ? -55.447 -15.581 -67.024 1.00 44.92 ? 206 LEU A C 1 +ATOM 883 O O . LEU A 1 144 ? -54.351 -16.069 -66.726 1.00 38.00 ? 206 LEU A O 1 +ATOM 884 C CB . LEU A 1 144 ? -57.829 -16.398 -67.168 1.00 51.71 ? 206 LEU A CB 1 +ATOM 885 C CG . LEU A 1 144 ? -59.051 -17.031 -66.491 1.00 52.59 ? 206 LEU A CG 1 +ATOM 886 C CD1 . LEU A 1 144 ? -60.000 -17.659 -67.503 1.00 59.47 ? 206 LEU A CD1 1 +ATOM 887 C CD2 . LEU A 1 144 ? -58.624 -18.064 -65.473 1.00 48.68 ? 206 LEU A CD2 1 +ATOM 888 N N . GLY A 1 145 ? -55.602 -14.691 -68.007 1.00 58.17 ? 207 GLY A N 1 +ATOM 889 C CA . GLY A 1 145 ? -54.505 -14.203 -68.825 1.00 53.08 ? 207 GLY A CA 1 +ATOM 890 C C . GLY A 1 145 ? -53.529 -13.346 -68.046 1.00 43.33 ? 207 GLY A C 1 +ATOM 891 O O . GLY A 1 145 ? -52.722 -13.893 -67.290 1.00 46.98 ? 207 GLY A O 1 +ATOM 892 N N . ALA A 1 146 ? -53.560 -12.022 -68.204 1.00 40.68 ? 208 ALA A N 1 +ATOM 893 C CA . ALA A 1 146 ? -54.392 -11.283 -69.153 1.00 45.43 ? 208 ALA A CA 1 +ATOM 894 C C . ALA A 1 146 ? -53.744 -9.915 -69.338 1.00 59.45 ? 208 ALA A C 1 +ATOM 895 O O . ALA A 1 146 ? -54.227 -8.904 -68.821 1.00 60.50 ? 208 ALA A O 1 +ATOM 896 C CB . ALA A 1 146 ? -55.824 -11.135 -68.660 1.00 46.91 ? 208 ALA A CB 1 +ATOM 897 N N . CYS A 1 147 ? -52.632 -9.895 -70.062 1.00 62.85 ? 209 CYS A N 1 +ATOM 898 C CA . CYS A 1 147 ? -51.772 -8.722 -70.158 1.00 55.22 ? 209 CYS A CA 1 +ATOM 899 C C . CYS A 1 147 ? -51.950 -8.084 -71.528 1.00 54.89 ? 209 CYS A C 1 +ATOM 900 O O . CYS A 1 147 ? -51.592 -8.679 -72.549 1.00 64.78 ? 209 CYS A O 1 +ATOM 901 C CB . CYS A 1 147 ? -50.322 -9.122 -69.918 1.00 53.78 ? 209 CYS A CB 1 +ATOM 902 S SG . CYS A 1 147 ? -49.379 -7.886 -69.038 1.00 70.49 ? 209 CYS A SG 1 +ATOM 903 N N . ASP A 1 148 ? -52.498 -6.873 -71.543 1.00 58.42 ? 210 ASP A N 1 +ATOM 904 C CA . ASP A 1 148 ? -52.664 -6.065 -72.750 1.00 56.67 ? 210 ASP A CA 1 +ATOM 905 C C . ASP A 1 148 ? -51.813 -4.813 -72.561 1.00 59.44 ? 210 ASP A C 1 +ATOM 906 O O . ASP A 1 148 ? -52.249 -3.845 -71.935 1.00 62.37 ? 210 ASP A O 1 +ATOM 907 C CB . ASP A 1 148 ? -54.132 -5.720 -72.983 1.00 55.97 ? 210 ASP A CB 1 +ATOM 908 C CG . ASP A 1 148 ? -54.373 -5.039 -74.320 1.00 65.12 ? 210 ASP A CG 1 +ATOM 909 O OD1 . ASP A 1 148 ? -53.420 -4.923 -75.123 1.00 66.38 ? 210 ASP A OD1 1 +ATOM 910 O OD2 . ASP A 1 148 ? -55.520 -4.594 -74.554 1.00 66.62 ? 210 ASP A OD2 1 +ATOM 911 N N . CYS A 1 149 ? -50.587 -4.841 -73.089 1.00 58.08 ? 211 CYS A N 1 +ATOM 912 C CA . CYS A 1 149 ? -49.675 -3.711 -72.935 1.00 60.22 ? 211 CYS A CA 1 +ATOM 913 C C . CYS A 1 149 ? -50.187 -2.435 -73.592 1.00 68.94 ? 211 CYS A C 1 +ATOM 914 O O . CYS A 1 149 ? -49.640 -1.358 -73.324 1.00 61.97 ? 211 CYS A O 1 +ATOM 915 C CB . CYS A 1 149 ? -48.308 -4.077 -73.509 1.00 57.86 ? 211 CYS A CB 1 +ATOM 916 S SG . CYS A 1 149 ? -47.556 -5.480 -72.676 1.00 73.84 ? 211 CYS A SG 1 +ATOM 917 N N . THR A 1 150 ? -51.217 -2.534 -74.439 1.00 74.33 ? 212 THR A N 1 +ATOM 918 C CA . THR A 1 150 ? -51.852 -1.368 -75.040 1.00 67.54 ? 212 THR A CA 1 +ATOM 919 C C . THR A 1 150 ? -52.829 -0.709 -74.073 1.00 64.63 ? 212 THR A C 1 +ATOM 920 O O . THR A 1 150 ? -52.987 0.518 -74.089 1.00 62.28 ? 212 THR A O 1 +ATOM 921 C CB . THR A 1 150 ? -52.570 -1.786 -76.328 1.00 63.02 ? 212 THR A CB 1 +ATOM 922 O OG1 . THR A 1 150 ? -51.600 -2.183 -77.304 1.00 64.62 ? 212 THR A OG1 1 +ATOM 923 C CG2 . THR A 1 150 ? -53.386 -0.640 -76.898 1.00 68.48 ? 212 THR A CG2 1 +ATOM 924 N N . GLN A 1 151 ? -53.474 -1.508 -73.225 1.00 68.06 ? 213 GLN A N 1 +ATOM 925 C CA . GLN A 1 151 ? -54.389 -1.000 -72.212 1.00 63.60 ? 213 GLN A CA 1 +ATOM 926 C C . GLN A 1 151 ? -53.673 -0.025 -71.290 1.00 57.18 ? 213 GLN A C 1 +ATOM 927 O O . GLN A 1 151 ? -52.746 -0.405 -70.568 1.00 52.08 ? 213 GLN A O 1 +ATOM 928 C CB . GLN A 1 151 ? -54.952 -2.164 -71.404 1.00 61.68 ? 213 GLN A CB 1 +ATOM 929 C CG . GLN A 1 151 ? -56.380 -2.001 -70.948 1.00 60.71 ? 213 GLN A CG 1 +ATOM 930 C CD . GLN A 1 151 ? -56.875 -3.247 -70.243 1.00 64.98 ? 213 GLN A CD 1 +ATOM 931 O OE1 . GLN A 1 151 ? -56.097 -4.169 -69.980 1.00 58.00 ? 213 GLN A OE1 1 +ATOM 932 N NE2 . GLN A 1 151 ? -58.172 -3.292 -69.945 1.00 72.48 ? 213 GLN A NE2 1 +ATOM 933 N N . ILE A 1 152 ? -54.119 1.229 -71.294 1.00 59.04 ? 214 ILE A N 1 +ATOM 934 C CA . ILE A 1 152 ? -53.475 2.229 -70.453 1.00 49.47 ? 214 ILE A CA 1 +ATOM 935 C C . ILE A 1 152 ? -53.921 2.071 -69.009 1.00 44.51 ? 214 ILE A C 1 +ATOM 936 O O . ILE A 1 152 ? -53.098 2.070 -68.088 1.00 39.01 ? 214 ILE A O 1 +ATOM 937 C CB . ILE A 1 152 ? -53.782 3.636 -70.998 1.00 48.91 ? 214 ILE A CB 1 +ATOM 938 C CG1 . ILE A 1 152 ? -53.301 3.758 -72.444 1.00 49.39 ? 214 ILE A CG1 1 +ATOM 939 C CG2 . ILE A 1 152 ? -53.119 4.697 -70.137 1.00 46.74 ? 214 ILE A CG2 1 +ATOM 940 C CD1 . ILE A 1 152 ? -53.589 5.097 -73.071 1.00 48.51 ? 214 ILE A CD1 1 +ATOM 941 N N . VAL A 1 153 ? -55.222 1.884 -68.795 1.00 49.46 ? 215 VAL A N 1 +ATOM 942 C CA . VAL A 1 153 ? -55.766 1.656 -67.463 1.00 50.55 ? 215 VAL A CA 1 +ATOM 943 C C . VAL A 1 153 ? -56.203 0.202 -67.371 1.00 55.13 ? 215 VAL A C 1 +ATOM 944 O O . VAL A 1 153 ? -57.399 -0.108 -67.441 1.00 49.60 ? 215 VAL A O 1 +ATOM 945 C CB . VAL A 1 153 ? -56.935 2.606 -67.147 1.00 56.78 ? 215 VAL A CB 1 +ATOM 946 C CG1 . VAL A 1 153 ? -57.233 2.590 -65.658 1.00 54.08 ? 215 VAL A CG1 1 +ATOM 947 C CG2 . VAL A 1 153 ? -56.623 4.016 -67.616 1.00 60.03 ? 215 VAL A CG2 1 +ATOM 948 N N . LYS A 1 154 ? -55.228 -0.698 -67.269 1.00 57.95 ? 216 LYS A N 1 +ATOM 949 C CA . LYS A 1 154 ? -55.519 -2.107 -67.069 1.00 55.29 ? 216 LYS A CA 1 +ATOM 950 C C . LYS A 1 154 ? -56.248 -2.298 -65.738 1.00 53.88 ? 216 LYS A C 1 +ATOM 951 O O . LYS A 1 154 ? -56.055 -1.511 -64.807 1.00 61.38 ? 216 LYS A O 1 +ATOM 952 C CB . LYS A 1 154 ? -54.221 -2.910 -67.105 1.00 52.58 ? 216 LYS A CB 1 +ATOM 953 C CG . LYS A 1 154 ? -52.984 -2.093 -66.751 1.00 49.35 ? 216 LYS A CG 1 +ATOM 954 C CD . LYS A 1 154 ? -51.703 -2.879 -67.011 1.00 49.94 ? 216 LYS A CD 1 +ATOM 955 C CE . LYS A 1 154 ? -51.479 -3.133 -68.491 1.00 45.17 ? 216 LYS A CE 1 +ATOM 956 N NZ . LYS A 1 154 ? -50.841 -1.961 -69.146 1.00 50.31 ? 216 LYS A NZ 1 +ATOM 957 N N . PRO A 1 155 ? -57.075 -3.342 -65.614 1.00 54.63 ? 217 PRO A N 1 +ATOM 958 C CA . PRO A 1 155 ? -57.933 -3.473 -64.428 1.00 65.21 ? 217 PRO A CA 1 +ATOM 959 C C . PRO A 1 155 ? -57.123 -3.575 -63.142 1.00 77.31 ? 217 PRO A C 1 +ATOM 960 O O . PRO A 1 155 ? -55.918 -3.838 -63.154 1.00 75.39 ? 217 PRO A O 1 +ATOM 961 C CB . PRO A 1 155 ? -58.721 -4.761 -64.697 1.00 53.49 ? 217 PRO A CB 1 +ATOM 962 C CG . PRO A 1 155 ? -57.880 -5.520 -65.652 1.00 49.13 ? 217 PRO A CG 1 +ATOM 963 C CD . PRO A 1 155 ? -57.248 -4.483 -66.528 1.00 56.38 ? 217 PRO A CD 1 +ATOM 964 N N . SER A 1 156 ? -57.811 -3.376 -62.013 1.00 70.33 ? 218 SER A N 1 +ATOM 965 C CA . SER A 1 156 ? -57.141 -3.316 -60.716 1.00 72.39 ? 218 SER A CA 1 +ATOM 966 C C . SER A 1 156 ? -56.663 -4.691 -60.261 1.00 66.85 ? 218 SER A C 1 +ATOM 967 O O . SER A 1 156 ? -56.367 -4.887 -59.079 1.00 77.49 ? 218 SER A O 1 +ATOM 968 C CB . SER A 1 156 ? -58.080 -2.698 -59.665 1.00 80.79 ? 218 SER A CB 1 +ATOM 969 O OG . SER A 1 156 ? -57.443 -2.518 -58.405 1.00 74.97 ? 218 SER A OG 1 +ATOM 970 N N . GLY A 1 157 ? -56.526 -5.632 -61.190 1.00 59.01 ? 219 GLY A N 1 +ATOM 971 C CA . GLY A 1 157 ? -56.067 -6.956 -60.833 1.00 59.66 ? 219 GLY A CA 1 +ATOM 972 C C . GLY A 1 157 ? -54.618 -7.196 -61.191 1.00 60.84 ? 219 GLY A C 1 +ATOM 973 O O . GLY A 1 157 ? -54.000 -8.144 -60.703 1.00 59.00 ? 219 GLY A O 1 +ATOM 974 N N . VAL A 1 158 ? -54.039 -6.314 -61.996 1.00 61.81 ? 220 VAL A N 1 +ATOM 975 C CA . VAL A 1 158 ? -52.647 -6.480 -62.391 1.00 58.35 ? 220 VAL A CA 1 +ATOM 976 C C . VAL A 1 158 ? -51.774 -5.609 -61.502 1.00 60.00 ? 220 VAL A C 1 +ATOM 977 O O . VAL A 1 158 ? -50.841 -4.962 -61.982 1.00 72.16 ? 220 VAL A O 1 +ATOM 978 C CB . VAL A 1 158 ? -52.444 -6.126 -63.876 1.00 59.33 ? 220 VAL A CB 1 +ATOM 979 C CG1 . VAL A 1 158 ? -53.040 -7.199 -64.765 1.00 65.27 ? 220 VAL A CG1 1 +ATOM 980 C CG2 . VAL A 1 158 ? -53.095 -4.792 -64.180 1.00 61.78 ? 220 VAL A CG2 1 +ATOM 981 N N . HIS A 1 159 ? -52.044 -5.608 -60.202 1.00 48.92 ? 221 HIS A N 1 +ATOM 982 C CA . HIS A 1 159 ? -51.278 -4.812 -59.260 1.00 44.18 ? 221 HIS A CA 1 +ATOM 983 C C . HIS A 1 159 ? -50.634 -5.727 -58.231 1.00 38.67 ? 221 HIS A C 1 +ATOM 984 O O . HIS A 1 159 ? -51.210 -6.748 -57.841 1.00 39.31 ? 221 HIS A O 1 +ATOM 985 C CB . HIS A 1 159 ? -52.167 -3.771 -58.558 1.00 60.39 ? 221 HIS A CB 1 +ATOM 986 C CG . HIS A 1 159 ? -52.684 -2.693 -59.464 1.00 63.35 ? 221 HIS A CG 1 +ATOM 987 N ND1 . HIS A 1 159 ? -51.967 -2.205 -60.536 1.00 65.19 ? 221 HIS A ND1 1 +ATOM 988 C CD2 . HIS A 1 159 ? -53.861 -2.023 -59.465 1.00 57.40 ? 221 HIS A CD2 1 +ATOM 989 C CE1 . HIS A 1 159 ? -52.675 -1.274 -61.151 1.00 57.32 ? 221 HIS A CE1 1 +ATOM 990 N NE2 . HIS A 1 159 ? -53.829 -1.146 -60.522 1.00 57.54 ? 221 HIS A NE2 1 +ATOM 991 N N . LEU A 1 160 ? -49.439 -5.344 -57.786 1.00 44.93 ? 222 LEU A N 1 +ATOM 992 C CA . LEU A 1 160 ? -48.636 -6.171 -56.882 1.00 44.52 ? 222 LEU A CA 1 +ATOM 993 C C . LEU A 1 160 ? -49.243 -6.146 -55.486 1.00 41.64 ? 222 LEU A C 1 +ATOM 994 O O . LEU A 1 160 ? -49.032 -5.206 -54.717 1.00 41.78 ? 222 LEU A O 1 +ATOM 995 C CB . LEU A 1 160 ? -47.192 -5.685 -56.853 1.00 38.05 ? 222 LEU A CB 1 +ATOM 996 C CG . LEU A 1 160 ? -46.123 -6.776 -56.747 1.00 41.89 ? 222 LEU A CG 1 +ATOM 997 C CD1 . LEU A 1 160 ? -44.733 -6.173 -56.845 1.00 48.51 ? 222 LEU A CD1 1 +ATOM 998 C CD2 . LEU A 1 160 ? -46.268 -7.598 -55.478 1.00 38.00 ? 222 LEU A CD2 1 +ATOM 999 N N . LYS A 1 161 ? -49.972 -7.206 -55.144 1.00 42.12 ? 223 LYS A N 1 +ATOM 1000 C CA . LYS A 1 161 ? -50.540 -7.372 -53.816 1.00 39.24 ? 223 LYS A CA 1 +ATOM 1001 C C . LYS A 1 161 ? -50.783 -8.856 -53.586 1.00 42.15 ? 223 LYS A C 1 +ATOM 1002 O O . LYS A 1 161 ? -51.179 -9.575 -54.508 1.00 45.12 ? 223 LYS A O 1 +ATOM 1003 C CB . LYS A 1 161 ? -51.839 -6.574 -53.643 1.00 38.00 ? 223 LYS A CB 1 +ATOM 1004 C CG . LYS A 1 161 ? -52.985 -6.990 -54.556 1.00 41.07 ? 223 LYS A CG 1 +ATOM 1005 C CD . LYS A 1 161 ? -54.182 -6.076 -54.352 1.00 46.61 ? 223 LYS A CD 1 +ATOM 1006 C CE . LYS A 1 161 ? -55.121 -6.097 -55.543 1.00 50.02 ? 223 LYS A CE 1 +ATOM 1007 N NZ . LYS A 1 161 ? -56.244 -5.125 -55.379 1.00 54.14 ? 223 LYS A NZ 1 +ATOM 1008 N N . LEU A 1 162 ? -50.520 -9.307 -52.362 1.00 41.16 ? 224 LEU A N 1 +ATOM 1009 C CA . LEU A 1 162 ? -50.693 -10.695 -51.963 1.00 38.00 ? 224 LEU A CA 1 +ATOM 1010 C C . LEU A 1 162 ? -51.668 -10.765 -50.802 1.00 39.72 ? 224 LEU A C 1 +ATOM 1011 O O . LEU A 1 162 ? -51.998 -9.755 -50.177 1.00 46.03 ? 224 LEU A O 1 +ATOM 1012 C CB . LEU A 1 162 ? -49.366 -11.329 -51.538 1.00 38.00 ? 224 LEU A CB 1 +ATOM 1013 C CG . LEU A 1 162 ? -48.212 -11.147 -52.506 1.00 38.00 ? 224 LEU A CG 1 +ATOM 1014 C CD1 . LEU A 1 162 ? -46.951 -11.765 -51.940 1.00 38.00 ? 224 LEU A CD1 1 +ATOM 1015 C CD2 . LEU A 1 162 ? -48.586 -11.762 -53.836 1.00 46.83 ? 224 LEU A CD2 1 +ATOM 1016 N N . VAL A 1 163 ? -52.142 -11.973 -50.520 1.00 38.58 ? 225 VAL A N 1 +ATOM 1017 C CA . VAL A 1 163 ? -53.006 -12.223 -49.374 1.00 40.65 ? 225 VAL A CA 1 +ATOM 1018 C C . VAL A 1 163 ? -52.287 -13.207 -48.459 1.00 40.68 ? 225 VAL A C 1 +ATOM 1019 O O . VAL A 1 163 ? -52.012 -14.348 -48.852 1.00 38.54 ? 225 VAL A O 1 +ATOM 1020 C CB . VAL A 1 163 ? -54.387 -12.745 -49.789 1.00 38.00 ? 225 VAL A CB 1 +ATOM 1021 C CG1 . VAL A 1 163 ? -54.251 -13.780 -50.874 1.00 38.08 ? 225 VAL A CG1 1 +ATOM 1022 C CG2 . VAL A 1 163 ? -55.092 -13.327 -48.581 1.00 41.98 ? 225 VAL A CG2 1 +ATOM 1023 N N . LEU A 1 164 ? -51.986 -12.767 -47.245 1.00 40.95 ? 226 LEU A N 1 +ATOM 1024 C CA . LEU A 1 164 ? -51.212 -13.552 -46.300 1.00 45.87 ? 226 LEU A CA 1 +ATOM 1025 C C . LEU A 1 164 ? -52.117 -14.166 -45.234 1.00 49.95 ? 226 LEU A C 1 +ATOM 1026 O O . LEU A 1 164 ? -53.184 -13.635 -44.913 1.00 47.85 ? 226 LEU A O 1 +ATOM 1027 C CB . LEU A 1 164 ? -50.134 -12.681 -45.648 1.00 41.30 ? 226 LEU A CB 1 +ATOM 1028 C CG . LEU A 1 164 ? -48.795 -12.516 -46.377 1.00 38.00 ? 226 LEU A CG 1 +ATOM 1029 C CD1 . LEU A 1 164 ? -48.963 -12.421 -47.875 1.00 38.00 ? 226 LEU A CD1 1 +ATOM 1030 C CD2 . LEU A 1 164 ? -48.052 -11.303 -45.856 1.00 38.00 ? 226 LEU A CD2 1 +ATOM 1031 N N . ARG A 1 165 ? -51.678 -15.300 -44.692 1.00 48.62 ? 227 ARG A N 1 +ATOM 1032 C CA . ARG A 1 165 ? -52.372 -15.982 -43.610 1.00 51.95 ? 227 ARG A CA 1 +ATOM 1033 C C . ARG A 1 165 ? -51.428 -16.148 -42.434 1.00 52.89 ? 227 ARG A C 1 +ATOM 1034 O O . ARG A 1 165 ? -50.245 -16.461 -42.607 1.00 49.16 ? 227 ARG A O 1 +ATOM 1035 C CB . ARG A 1 165 ? -52.895 -17.361 -44.018 1.00 57.49 ? 227 ARG A CB 1 +ATOM 1036 C CG . ARG A 1 165 ? -53.613 -17.388 -45.340 1.00 70.27 ? 227 ARG A CG 1 +ATOM 1037 C CD . ARG A 1 165 ? -54.639 -18.503 -45.386 1.00 62.13 ? 227 ARG A CD 1 +ATOM 1038 N NE . ARG A 1 165 ? -55.715 -18.268 -44.431 1.00 47.11 ? 227 ARG A NE 1 +ATOM 1039 C CZ . ARG A 1 165 ? -56.940 -18.754 -44.572 1.00 47.67 ? 227 ARG A CZ 1 +ATOM 1040 N NH1 . ARG A 1 165 ? -57.242 -19.487 -45.633 1.00 52.24 ? 227 ARG A NH1 1 +ATOM 1041 N NH2 . ARG A 1 165 ? -57.866 -18.488 -43.669 1.00 49.00 ? 227 ARG A NH2 1 +ATOM 1042 N N . PHE A 1 166 ? -51.952 -15.915 -41.243 1.00 51.35 ? 228 PHE A N 1 +ATOM 1043 C CA . PHE A 1 166 ? -51.174 -15.996 -40.024 1.00 46.55 ? 228 PHE A CA 1 +ATOM 1044 C C . PHE A 1 166 ? -51.583 -17.222 -39.226 1.00 44.60 ? 228 PHE A C 1 +ATOM 1045 O O . PHE A 1 166 ? -52.569 -17.901 -39.529 1.00 45.40 ? 228 PHE A O 1 +ATOM 1046 C CB . PHE A 1 166 ? -51.361 -14.735 -39.189 1.00 53.62 ? 228 PHE A CB 1 +ATOM 1047 C CG . PHE A 1 166 ? -51.197 -13.474 -39.966 1.00 49.32 ? 228 PHE A CG 1 +ATOM 1048 C CD1 . PHE A 1 166 ? -49.935 -12.974 -40.248 1.00 44.42 ? 228 PHE A CD1 1 +ATOM 1049 C CD2 . PHE A 1 166 ? -52.307 -12.801 -40.438 1.00 45.47 ? 228 PHE A CD2 1 +ATOM 1050 C CE1 . PHE A 1 166 ? -49.789 -11.811 -40.965 1.00 42.87 ? 228 PHE A CE1 1 +ATOM 1051 C CE2 . PHE A 1 166 ? -52.171 -11.643 -41.159 1.00 46.91 ? 228 PHE A CE2 1 +ATOM 1052 C CZ . PHE A 1 166 ? -50.911 -11.145 -41.423 1.00 48.42 ? 228 PHE A CZ 1 +ATOM 1053 N N . SER A 1 167 ? -50.821 -17.467 -38.161 1.00 40.09 ? 229 SER A N 1 +ATOM 1054 C CA . SER A 1 167 ? -51.026 -18.658 -37.354 1.00 38.45 ? 229 SER A CA 1 +ATOM 1055 C C . SER A 1 167 ? -52.400 -18.696 -36.699 1.00 38.16 ? 229 SER A C 1 +ATOM 1056 O O . SER A 1 167 ? -52.879 -19.782 -36.364 1.00 49.38 ? 229 SER A O 1 +ATOM 1057 C CB . SER A 1 167 ? -49.938 -18.743 -36.291 1.00 41.85 ? 229 SER A CB 1 +ATOM 1058 O OG . SER A 1 167 ? -49.940 -17.568 -35.506 1.00 49.24 ? 229 SER A OG 1 +ATOM 1059 N N . ASP A 1 168 ? -53.055 -17.555 -36.513 1.00 38.90 ? 230 ASP A N 1 +ATOM 1060 C CA . ASP A 1 168 ? -54.406 -17.577 -35.973 1.00 38.50 ? 230 ASP A CA 1 +ATOM 1061 C C . ASP A 1 168 ? -55.461 -17.743 -37.061 1.00 42.13 ? 230 ASP A C 1 +ATOM 1062 O O . ASP A 1 168 ? -56.648 -17.535 -36.791 1.00 43.57 ? 230 ASP A O 1 +ATOM 1063 C CB . ASP A 1 168 ? -54.671 -16.320 -35.128 1.00 42.09 ? 230 ASP A CB 1 +ATOM 1064 C CG . ASP A 1 168 ? -54.589 -15.028 -35.925 1.00 48.56 ? 230 ASP A CG 1 +ATOM 1065 O OD1 . ASP A 1 168 ? -54.230 -15.072 -37.118 1.00 58.69 ? 230 ASP A OD1 1 +ATOM 1066 O OD2 . ASP A 1 168 ? -54.875 -13.957 -35.348 1.00 45.29 ? 230 ASP A OD2 1 +ATOM 1067 N N . PHE A 1 169 ? -55.050 -18.120 -38.274 1.00 40.37 ? 231 PHE A N 1 +ATOM 1068 C CA . PHE A 1 169 ? -55.860 -18.423 -39.450 1.00 46.70 ? 231 PHE A CA 1 +ATOM 1069 C C . PHE A 1 169 ? -56.342 -17.163 -40.164 1.00 53.69 ? 231 PHE A C 1 +ATOM 1070 O O . PHE A 1 169 ? -56.869 -17.270 -41.271 1.00 60.88 ? 231 PHE A O 1 +ATOM 1071 C CB . PHE A 1 169 ? -57.080 -19.313 -39.134 1.00 49.43 ? 231 PHE A CB 1 +ATOM 1072 C CG . PHE A 1 169 ? -57.676 -19.997 -40.336 1.00 56.47 ? 231 PHE A CG 1 +ATOM 1073 C CD1 . PHE A 1 169 ? -56.994 -21.015 -40.981 1.00 57.10 ? 231 PHE A CD1 1 +ATOM 1074 C CD2 . PHE A 1 169 ? -58.936 -19.642 -40.801 1.00 62.77 ? 231 PHE A CD2 1 +ATOM 1075 C CE1 . PHE A 1 169 ? -57.550 -21.654 -42.082 1.00 60.19 ? 231 PHE A CE1 1 +ATOM 1076 C CE2 . PHE A 1 169 ? -59.500 -20.282 -41.899 1.00 56.94 ? 231 PHE A CE2 1 +ATOM 1077 C CZ . PHE A 1 169 ? -58.804 -21.286 -42.539 1.00 55.77 ? 231 PHE A CZ 1 +ATOM 1078 N N . GLY A 1 170 ? -56.184 -15.977 -39.582 1.00 53.87 ? 232 GLY A N 1 +ATOM 1079 C CA . GLY A 1 170 ? -56.673 -14.766 -40.209 1.00 57.21 ? 232 GLY A CA 1 +ATOM 1080 C C . GLY A 1 170 ? -55.898 -14.385 -41.455 1.00 57.60 ? 232 GLY A C 1 +ATOM 1081 O O . GLY A 1 170 ? -54.797 -14.868 -41.726 1.00 56.59 ? 232 GLY A O 1 +ATOM 1082 N N . LYS A 1 171 ? -56.489 -13.478 -42.226 1.00 51.97 ? 233 LYS A N 1 +ATOM 1083 C CA . LYS A 1 171 ? -55.891 -13.018 -43.467 1.00 52.40 ? 233 LYS A CA 1 +ATOM 1084 C C . LYS A 1 171 ? -55.733 -11.503 -43.456 1.00 52.71 ? 233 LYS A C 1 +ATOM 1085 O O . LYS A 1 171 ? -56.342 -10.787 -42.655 1.00 48.81 ? 233 LYS A O 1 +ATOM 1086 C CB . LYS A 1 171 ? -56.724 -13.444 -44.680 1.00 50.02 ? 233 LYS A CB 1 +ATOM 1087 C CG . LYS A 1 171 ? -56.833 -14.931 -44.873 1.00 48.81 ? 233 LYS A CG 1 +ATOM 1088 C CD . LYS A 1 171 ? -57.524 -15.242 -46.190 1.00 50.55 ? 233 LYS A CD 1 +ATOM 1089 C CE . LYS A 1 171 ? -59.030 -15.285 -46.013 1.00 54.63 ? 233 LYS A CE 1 +ATOM 1090 N NZ . LYS A 1 171 ? -59.716 -15.761 -47.236 1.00 62.22 ? 233 LYS A NZ 1 +ATOM 1091 N N . ALA A 1 172 ? -54.919 -11.024 -44.394 1.00 45.87 ? 234 ALA A N 1 +ATOM 1092 C CA . ALA A 1 172 ? -54.600 -9.612 -44.508 1.00 40.87 ? 234 ALA A CA 1 +ATOM 1093 C C . ALA A 1 172 ? -54.045 -9.358 -45.900 1.00 42.56 ? 234 ALA A C 1 +ATOM 1094 O O . ALA A 1 172 ? -53.267 -10.162 -46.412 1.00 45.22 ? 234 ALA A O 1 +ATOM 1095 C CB . ALA A 1 172 ? -53.581 -9.189 -43.447 1.00 38.00 ? 234 ALA A CB 1 +ATOM 1096 N N . MET A 1 173 ? -54.445 -8.238 -46.498 1.00 42.87 ? 235 MET A N 1 +ATOM 1097 C CA . MET A 1 173 ? -54.008 -7.862 -47.836 1.00 38.00 ? 235 MET A CA 1 +ATOM 1098 C C . MET A 1 173 ? -52.681 -7.119 -47.738 1.00 38.00 ? 235 MET A C 1 +ATOM 1099 O O . MET A 1 173 ? -52.602 -6.062 -47.103 1.00 38.00 ? 235 MET A O 1 +ATOM 1100 C CB . MET A 1 173 ? -55.065 -7.001 -48.525 1.00 39.23 ? 235 MET A CB 1 +ATOM 1101 C CG . MET A 1 173 ? -54.792 -6.702 -49.998 1.00 51.83 ? 235 MET A CG 1 +ATOM 1102 S SD . MET A 1 173 ? -54.828 -8.154 -51.076 1.00 50.09 ? 235 MET A SD 1 +ATOM 1103 C CE . MET A 1 173 ? -56.512 -8.698 -50.828 1.00 54.29 ? 235 MET A CE 1 +ATOM 1104 N N . PHE A 1 174 ? -51.644 -7.680 -48.352 1.00 38.00 ? 236 PHE A N 1 +ATOM 1105 C CA . PHE A 1 174 ? -50.283 -7.167 -48.272 1.00 38.00 ? 236 PHE A CA 1 +ATOM 1106 C C . PHE A 1 174 ? -49.984 -6.273 -49.472 1.00 40.05 ? 236 PHE A C 1 +ATOM 1107 O O . PHE A 1 174 ? -50.107 -6.709 -50.621 1.00 42.73 ? 236 PHE A O 1 +ATOM 1108 C CB . PHE A 1 174 ? -49.299 -8.332 -48.217 1.00 38.00 ? 236 PHE A CB 1 +ATOM 1109 C CG . PHE A 1 174 ? -47.856 -7.924 -48.223 1.00 38.00 ? 236 PHE A CG 1 +ATOM 1110 C CD1 . PHE A 1 174 ? -47.234 -7.518 -47.061 1.00 38.00 ? 236 PHE A CD1 1 +ATOM 1111 C CD2 . PHE A 1 174 ? -47.115 -7.971 -49.390 1.00 38.00 ? 236 PHE A CD2 1 +ATOM 1112 C CE1 . PHE A 1 174 ? -45.901 -7.160 -47.061 1.00 38.00 ? 236 PHE A CE1 1 +ATOM 1113 C CE2 . PHE A 1 174 ? -45.785 -7.611 -49.397 1.00 38.00 ? 236 PHE A CE2 1 +ATOM 1114 C CZ . PHE A 1 174 ? -45.176 -7.204 -48.229 1.00 38.00 ? 236 PHE A CZ 1 +ATOM 1115 N N . LYS A 1 175 ? -49.596 -5.028 -49.200 1.00 38.00 ? 237 LYS A N 1 +ATOM 1116 C CA . LYS A 1 175 ? -49.152 -4.072 -50.208 1.00 38.00 ? 237 LYS A CA 1 +ATOM 1117 C C . LYS A 1 175 ? -47.705 -3.700 -49.912 1.00 38.00 ? 237 LYS A C 1 +ATOM 1118 O O . LYS A 1 175 ? -47.421 -3.164 -48.828 1.00 38.00 ? 237 LYS A O 1 +ATOM 1119 C CB . LYS A 1 175 ? -50.040 -2.830 -50.206 1.00 38.00 ? 237 LYS A CB 1 +ATOM 1120 C CG . LYS A 1 175 ? -51.494 -3.089 -50.557 1.00 38.00 ? 237 LYS A CG 1 +ATOM 1121 C CD . LYS A 1 175 ? -51.792 -2.718 -52.000 1.00 38.86 ? 237 LYS A CD 1 +ATOM 1122 C CE . LYS A 1 175 ? -53.282 -2.841 -52.322 1.00 46.99 ? 237 LYS A CE 1 +ATOM 1123 N NZ . LYS A 1 175 ? -54.169 -1.969 -51.495 1.00 45.33 ? 237 LYS A NZ 1 +ATOM 1124 N N . PRO A 1 176 ? -46.760 -3.985 -50.799 1.00 38.00 ? 238 PRO A N 1 +ATOM 1125 C CA . PRO A 1 176 ? -45.349 -3.716 -50.507 1.00 39.19 ? 238 PRO A CA 1 +ATOM 1126 C C . PRO A 1 176 ? -44.976 -2.250 -50.706 1.00 41.74 ? 238 PRO A C 1 +ATOM 1127 O O . PRO A 1 176 ? -45.730 -1.445 -51.255 1.00 39.92 ? 238 PRO A O 1 +ATOM 1128 C CB . PRO A 1 176 ? -44.612 -4.609 -51.509 1.00 39.78 ? 238 PRO A CB 1 +ATOM 1129 C CG . PRO A 1 176 ? -45.535 -4.668 -52.670 1.00 43.30 ? 238 PRO A CG 1 +ATOM 1130 C CD . PRO A 1 176 ? -46.936 -4.651 -52.101 1.00 49.20 ? 238 PRO A CD 1 +ATOM 1131 N N . MET A 1 177 ? -43.773 -1.921 -50.240 1.00 43.73 ? 239 MET A N 1 +ATOM 1132 C CA . MET A 1 177 ? -43.231 -0.583 -50.421 1.00 42.28 ? 239 MET A CA 1 +ATOM 1133 C C . MET A 1 177 ? -42.880 -0.353 -51.884 1.00 46.41 ? 239 MET A C 1 +ATOM 1134 O O . MET A 1 177 ? -42.102 -1.108 -52.474 1.00 47.26 ? 239 MET A O 1 +ATOM 1135 C CB . MET A 1 177 ? -41.989 -0.402 -49.555 1.00 40.28 ? 239 MET A CB 1 +ATOM 1136 C CG . MET A 1 177 ? -41.343 0.951 -49.694 1.00 43.83 ? 239 MET A CG 1 +ATOM 1137 S SD . MET A 1 177 ? -39.981 1.185 -48.541 1.00 39.32 ? 239 MET A SD 1 +ATOM 1138 C CE . MET A 1 177 ? -38.718 0.164 -49.297 1.00 38.00 ? 239 MET A CE 1 +ATOM 1139 N N . ARG A 1 178 ? -43.390 0.739 -52.446 1.00 52.15 ? 240 ARG A N 1 +ATOM 1140 C CA . ARG A 1 178 ? -43.207 1.040 -53.855 1.00 47.22 ? 240 ARG A CA 1 +ATOM 1141 C C . ARG A 1 178 ? -42.539 2.386 -54.090 1.00 50.89 ? 240 ARG A C 1 +ATOM 1142 O O . ARG A 1 178 ? -42.253 2.724 -55.244 1.00 46.55 ? 240 ARG A O 1 +ATOM 1143 C CB . ARG A 1 178 ? -44.563 1.008 -54.577 1.00 50.55 ? 240 ARG A CB 1 +ATOM 1144 C CG . ARG A 1 178 ? -45.370 -0.263 -54.339 1.00 51.27 ? 240 ARG A CG 1 +ATOM 1145 C CD . ARG A 1 178 ? -45.280 -1.192 -55.532 1.00 55.97 ? 240 ARG A CD 1 +ATOM 1146 N NE . ARG A 1 178 ? -44.015 -1.029 -56.239 1.00 54.53 ? 240 ARG A NE 1 +ATOM 1147 C CZ . ARG A 1 178 ? -43.702 -1.670 -57.358 1.00 55.13 ? 240 ARG A CZ 1 +ATOM 1148 N NH1 . ARG A 1 178 ? -44.564 -2.525 -57.888 1.00 53.88 ? 240 ARG A NH1 1 +ATOM 1149 N NH2 . ARG A 1 178 ? -42.530 -1.456 -57.943 1.00 53.58 ? 240 ARG A NH2 1 +ATOM 1150 N N . GLN A 1 179 ? -42.287 3.158 -53.033 1.00 52.27 ? 241 GLN A N 1 +ATOM 1151 C CA . GLN A 1 179 ? -41.698 4.486 -53.137 1.00 52.96 ? 241 GLN A CA 1 +ATOM 1152 C C . GLN A 1 179 ? -41.124 4.882 -51.786 1.00 50.85 ? 241 GLN A C 1 +ATOM 1153 O O . GLN A 1 179 ? -41.609 4.446 -50.740 1.00 58.66 ? 241 GLN A O 1 +ATOM 1154 C CB . GLN A 1 179 ? -42.731 5.524 -53.584 1.00 54.51 ? 241 GLN A CB 1 +ATOM 1155 C CG . GLN A 1 179 ? -42.688 5.861 -55.057 1.00 53.77 ? 241 GLN A CG 1 +ATOM 1156 C CD . GLN A 1 179 ? -43.579 7.029 -55.388 1.00 49.83 ? 241 GLN A CD 1 +ATOM 1157 O OE1 . GLN A 1 179 ? -44.596 7.258 -54.726 1.00 40.91 ? 241 GLN A OE1 1 +ATOM 1158 N NE2 . GLN A 1 179 ? -43.206 7.781 -56.415 1.00 56.03 ? 241 GLN A NE2 1 +ATOM 1159 N N . GLN A 1 180 ? -40.114 5.747 -51.824 1.00 53.57 ? 242 GLN A N 1 +ATOM 1160 C CA . GLN A 1 180 ? -39.511 6.290 -50.615 1.00 56.70 ? 242 GLN A CA 1 +ATOM 1161 C C . GLN A 1 180 ? -40.507 7.202 -49.886 1.00 59.54 ? 242 GLN A C 1 +ATOM 1162 O O . GLN A 1 180 ? -41.633 7.432 -50.340 1.00 59.54 ? 242 GLN A O 1 +ATOM 1163 C CB . GLN A 1 180 ? -38.229 7.039 -50.969 1.00 58.28 ? 242 GLN A CB 1 +ATOM 1164 C CG . GLN A 1 180 ? -37.161 6.155 -51.572 1.00 50.04 ? 242 GLN A CG 1 +ATOM 1165 C CD . GLN A 1 180 ? -36.654 5.133 -50.588 1.00 49.44 ? 242 GLN A CD 1 +ATOM 1166 O OE1 . GLN A 1 180 ? -36.661 5.366 -49.384 1.00 60.91 ? 242 GLN A OE1 1 +ATOM 1167 N NE2 . GLN A 1 180 ? -36.206 3.993 -51.092 1.00 57.62 ? 242 GLN A NE2 1 +ATOM 1168 N N . ARG A 1 181 ? -40.097 7.705 -48.714 1.00 54.66 ? 243 ARG A N 1 +ATOM 1169 C CA . ARG A 1 181 ? -40.965 8.591 -47.936 1.00 57.25 ? 243 ARG A CA 1 +ATOM 1170 C C . ARG A 1 181 ? -41.027 9.990 -48.540 1.00 54.56 ? 243 ARG A C 1 +ATOM 1171 O O . ARG A 1 181 ? -42.115 10.546 -48.735 1.00 50.74 ? 243 ARG A O 1 +ATOM 1172 C CB . ARG A 1 181 ? -40.489 8.654 -46.483 1.00 48.63 ? 243 ARG A CB 1 +ATOM 1173 C CG . ARG A 1 181 ? -40.663 7.353 -45.754 1.00 46.04 ? 243 ARG A CG 1 +ATOM 1174 C CD . ARG A 1 181 ? -42.106 6.874 -45.848 1.00 43.15 ? 243 ARG A CD 1 +ATOM 1175 N NE . ARG A 1 181 ? -42.195 5.432 -45.662 1.00 45.69 ? 243 ARG A NE 1 +ATOM 1176 C CZ . ARG A 1 181 ? -42.182 4.826 -44.482 1.00 48.80 ? 243 ARG A CZ 1 +ATOM 1177 N NH1 . ARG A 1 181 ? -42.078 5.540 -43.371 1.00 45.67 ? 243 ARG A NH1 1 +ATOM 1178 N NH2 . ARG A 1 181 ? -42.262 3.503 -44.416 1.00 53.09 ? 243 ARG A NH2 1 +ATOM 1179 N N . ASP A 1 182 ? -39.869 10.563 -48.864 1.00 53.24 ? 244 ASP A N 1 +ATOM 1180 C CA . ASP A 1 182 ? -39.801 11.921 -49.384 1.00 48.09 ? 244 ASP A CA 1 +ATOM 1181 C C . ASP A 1 182 ? -40.040 11.960 -50.888 1.00 46.22 ? 244 ASP A C 1 +ATOM 1182 O O . ASP A 1 182 ? -39.548 12.861 -51.565 1.00 51.16 ? 244 ASP A O 1 +ATOM 1183 C CB . ASP A 1 182 ? -38.439 12.542 -49.072 1.00 55.17 ? 244 ASP A CB 1 +ATOM 1184 C CG . ASP A 1 182 ? -37.282 11.670 -49.541 1.00 67.09 ? 244 ASP A CG 1 +ATOM 1185 O OD1 . ASP A 1 182 ? -37.025 11.613 -50.764 1.00 59.39 ? 244 ASP A OD1 1 +ATOM 1186 O OD2 . ASP A 1 182 ? -36.623 11.042 -48.683 1.00 76.69 ? 244 ASP A OD2 1 +ATOM 1187 N N . GLU A 1 183 ? -40.785 10.993 -51.416 1.00 49.08 ? 245 GLU A N 1 +ATOM 1188 C CA . GLU A 1 183 ? -41.042 10.909 -52.846 1.00 51.94 ? 245 GLU A CA 1 +ATOM 1189 C C . GLU A 1 183 ? -42.513 11.169 -53.139 1.00 46.78 ? 245 GLU A C 1 +ATOM 1190 O O . GLU A 1 183 ? -43.396 10.666 -52.436 1.00 46.49 ? 245 GLU A O 1 +ATOM 1191 C CB . GLU A 1 183 ? -40.637 9.540 -53.404 1.00 51.88 ? 245 GLU A CB 1 +ATOM 1192 C CG . GLU A 1 183 ? -39.147 9.383 -53.667 1.00 55.27 ? 245 GLU A CG 1 +ATOM 1193 C CD . GLU A 1 183 ? -38.824 8.131 -54.465 1.00 60.40 ? 245 GLU A CD 1 +ATOM 1194 O OE1 . GLU A 1 183 ? -39.762 7.386 -54.822 1.00 62.00 ? 245 GLU A OE1 1 +ATOM 1195 O OE2 . GLU A 1 183 ? -37.630 7.896 -54.746 1.00 66.82 ? 245 GLU A OE2 1 +ATOM 1196 N N . GLU A 1 184 ? -42.769 11.960 -54.174 1.00 41.55 ? 246 GLU A N 1 +ATOM 1197 C CA . GLU A 1 184 ? -44.119 12.266 -54.619 1.00 43.41 ? 246 GLU A CA 1 +ATOM 1198 C C . GLU A 1 184 ? -44.404 11.566 -55.943 1.00 45.10 ? 246 GLU A C 1 +ATOM 1199 O O . GLU A 1 184 ? -43.490 11.112 -56.640 1.00 40.34 ? 246 GLU A O 1 +ATOM 1200 C CB . GLU A 1 184 ? -44.330 13.779 -54.773 1.00 47.74 ? 246 GLU A CB 1 +ATOM 1201 C CG . GLU A 1 184 ? -43.859 14.619 -53.591 1.00 48.45 ? 246 GLU A CG 1 +ATOM 1202 C CD . GLU A 1 184 ? -44.294 16.076 -53.693 1.00 50.58 ? 246 GLU A CD 1 +ATOM 1203 O OE1 . GLU A 1 184 ? -45.460 16.337 -54.068 1.00 50.45 ? 246 GLU A OE1 1 +ATOM 1204 O OE2 . GLU A 1 184 ? -43.456 16.963 -53.423 1.00 47.96 ? 246 GLU A OE2 1 +ATOM 1205 N N . THR A 1 185 ? -45.698 11.460 -56.270 1.00 45.29 ? 247 THR A N 1 +ATOM 1206 C CA . THR A 1 185 ? -46.092 11.069 -57.618 1.00 50.35 ? 247 THR A CA 1 +ATOM 1207 C C . THR A 1 185 ? -45.567 12.135 -58.567 1.00 59.17 ? 247 THR A C 1 +ATOM 1208 O O . THR A 1 185 ? -45.990 13.295 -58.491 1.00 66.43 ? 247 THR A O 1 +ATOM 1209 C CB . THR A 1 185 ? -47.612 10.925 -57.760 1.00 45.54 ? 247 THR A CB 1 +ATOM 1210 O OG1 . THR A 1 185 ? -48.106 11.862 -58.728 1.00 52.44 ? 247 THR A OG1 1 +ATOM 1211 C CG2 . THR A 1 185 ? -48.302 11.167 -56.448 1.00 39.48 ? 247 THR A CG2 1 +ATOM 1212 N N . PRO A 1 186 ? -44.633 11.792 -59.455 1.00 57.23 ? 248 PRO A N 1 +ATOM 1213 C CA . PRO A 1 186 ? -44.028 12.823 -60.303 1.00 65.55 ? 248 PRO A CA 1 +ATOM 1214 C C . PRO A 1 186 ? -45.072 13.484 -61.188 1.00 68.95 ? 248 PRO A C 1 +ATOM 1215 O O . PRO A 1 186 ? -46.058 12.865 -61.591 1.00 60.03 ? 248 PRO A O 1 +ATOM 1216 C CB . PRO A 1 186 ? -42.994 12.049 -61.127 1.00 66.25 ? 248 PRO A CB 1 +ATOM 1217 C CG . PRO A 1 186 ? -43.499 10.638 -61.130 1.00 63.30 ? 248 PRO A CG 1 +ATOM 1218 C CD . PRO A 1 186 ? -44.182 10.436 -59.811 1.00 54.08 ? 248 PRO A CD 1 +ATOM 1219 N N . VAL A 1 187 ? -44.869 14.779 -61.446 1.00 77.86 ? 249 VAL A N 1 +ATOM 1220 C CA . VAL A 1 187 ? -45.714 15.463 -62.410 1.00 66.33 ? 249 VAL A CA 1 +ATOM 1221 C C . VAL A 1 187 ? -45.582 14.750 -63.749 1.00 63.05 ? 249 VAL A C 1 +ATOM 1222 O O . VAL A 1 187 ? -44.567 14.103 -64.034 1.00 60.99 ? 249 VAL A O 1 +ATOM 1223 C CB . VAL A 1 187 ? -45.345 16.951 -62.520 1.00 71.73 ? 249 VAL A CB 1 +ATOM 1224 C CG1 . VAL A 1 187 ? -45.563 17.652 -61.178 1.00 75.79 ? 249 VAL A CG1 1 +ATOM 1225 C CG2 . VAL A 1 187 ? -43.899 17.098 -62.971 1.00 68.71 ? 249 VAL A CG2 1 +ATOM 1226 N N . ASP A 1 188 ? -46.632 14.857 -64.566 1.00 64.13 ? 250 ASP A N 1 +ATOM 1227 C CA . ASP A 1 188 ? -46.868 14.108 -65.809 1.00 66.22 ? 250 ASP A CA 1 +ATOM 1228 C C . ASP A 1 188 ? -47.451 12.731 -65.521 1.00 62.91 ? 250 ASP A C 1 +ATOM 1229 O O . ASP A 1 188 ? -47.531 11.901 -66.436 1.00 62.15 ? 250 ASP A O 1 +ATOM 1230 C CB . ASP A 1 188 ? -45.623 13.923 -66.689 1.00 63.55 ? 250 ASP A CB 1 +ATOM 1231 C CG . ASP A 1 188 ? -44.894 15.228 -66.970 1.00 61.64 ? 250 ASP A CG 1 +ATOM 1232 O OD1 . ASP A 1 188 ? -45.572 16.264 -67.149 1.00 67.39 ? 250 ASP A OD1 1 +ATOM 1233 O OD2 . ASP A 1 188 ? -43.641 15.209 -67.018 1.00 40.77 ? 250 ASP A OD2 1 +ATOM 1234 N N . PHE A 1 189 ? -47.862 12.456 -64.289 1.00 58.64 ? 251 PHE A N 1 +ATOM 1235 C CA . PHE A 1 189 ? -48.457 11.177 -63.930 1.00 47.69 ? 251 PHE A CA 1 +ATOM 1236 C C . PHE A 1 189 ? -49.942 11.383 -63.695 1.00 45.55 ? 251 PHE A C 1 +ATOM 1237 O O . PHE A 1 189 ? -50.335 12.125 -62.790 1.00 51.68 ? 251 PHE A O 1 +ATOM 1238 C CB . PHE A 1 189 ? -47.802 10.585 -62.685 1.00 56.18 ? 251 PHE A CB 1 +ATOM 1239 C CG . PHE A 1 189 ? -46.860 9.459 -62.976 1.00 63.27 ? 251 PHE A CG 1 +ATOM 1240 C CD1 . PHE A 1 189 ? -45.669 9.690 -63.641 1.00 70.21 ? 251 PHE A CD1 1 +ATOM 1241 C CD2 . PHE A 1 189 ? -47.163 8.169 -62.584 1.00 58.27 ? 251 PHE A CD2 1 +ATOM 1242 C CE1 . PHE A 1 189 ? -44.794 8.652 -63.905 1.00 64.01 ? 251 PHE A CE1 1 +ATOM 1243 C CE2 . PHE A 1 189 ? -46.298 7.131 -62.848 1.00 59.40 ? 251 PHE A CE2 1 +ATOM 1244 C CZ . PHE A 1 189 ? -45.111 7.373 -63.509 1.00 56.75 ? 251 PHE A CZ 1 +ATOM 1245 N N . PHE A 1 190 ? -50.761 10.741 -64.514 1.00 44.73 ? 252 PHE A N 1 +ATOM 1246 C CA . PHE A 1 190 ? -52.190 10.748 -64.276 1.00 51.94 ? 252 PHE A CA 1 +ATOM 1247 C C . PHE A 1 190 ? -52.516 9.924 -63.030 1.00 47.44 ? 252 PHE A C 1 +ATOM 1248 O O . PHE A 1 190 ? -51.664 9.233 -62.463 1.00 49.85 ? 252 PHE A O 1 +ATOM 1249 C CB . PHE A 1 190 ? -52.927 10.211 -65.500 1.00 55.23 ? 252 PHE A CB 1 +ATOM 1250 C CG . PHE A 1 190 ? -53.009 11.190 -66.631 1.00 57.11 ? 252 PHE A CG 1 +ATOM 1251 C CD1 . PHE A 1 190 ? -53.995 12.163 -66.648 1.00 69.82 ? 252 PHE A CD1 1 +ATOM 1252 C CD2 . PHE A 1 190 ? -52.093 11.152 -67.666 1.00 52.56 ? 252 PHE A CD2 1 +ATOM 1253 C CE1 . PHE A 1 190 ? -54.077 13.073 -67.688 1.00 71.01 ? 252 PHE A CE1 1 +ATOM 1254 C CE2 . PHE A 1 190 ? -52.167 12.058 -68.709 1.00 63.00 ? 252 PHE A CE2 1 +ATOM 1255 C CZ . PHE A 1 190 ? -53.161 13.021 -68.721 1.00 68.17 ? 252 PHE A CZ 1 +ATOM 1256 N N . TYR A 1 191 ? -53.771 10.011 -62.592 1.00 38.00 ? 253 TYR A N 1 +ATOM 1257 C CA . TYR A 1 191 ? -54.165 9.280 -61.396 1.00 38.00 ? 253 TYR A CA 1 +ATOM 1258 C C . TYR A 1 191 ? -54.094 7.771 -61.613 1.00 45.49 ? 253 TYR A C 1 +ATOM 1259 O O . TYR A 1 191 ? -53.609 7.042 -60.740 1.00 49.46 ? 253 TYR A O 1 +ATOM 1260 C CB . TYR A 1 191 ? -55.568 9.708 -60.962 1.00 43.39 ? 253 TYR A CB 1 +ATOM 1261 C CG . TYR A 1 191 ? -56.534 9.918 -62.106 1.00 49.87 ? 253 TYR A CG 1 +ATOM 1262 C CD1 . TYR A 1 191 ? -56.605 11.141 -62.761 1.00 53.33 ? 253 TYR A CD1 1 +ATOM 1263 C CD2 . TYR A 1 191 ? -57.398 8.910 -62.509 1.00 57.61 ? 253 TYR A CD2 1 +ATOM 1264 C CE1 . TYR A 1 191 ? -57.483 11.344 -63.806 1.00 56.57 ? 253 TYR A CE1 1 +ATOM 1265 C CE2 . TYR A 1 191 ? -58.285 9.107 -63.554 1.00 60.25 ? 253 TYR A CE2 1 +ATOM 1266 C CZ . TYR A 1 191 ? -58.321 10.326 -64.198 1.00 60.10 ? 253 TYR A CZ 1 +ATOM 1267 O OH . TYR A 1 191 ? -59.204 10.533 -65.233 1.00 63.20 ? 253 TYR A OH 1 +ATOM 1268 N N . PHE A 1 192 ? -54.505 7.285 -62.793 1.00 52.30 ? 254 PHE A N 1 +ATOM 1269 C CA . PHE A 1 192 ? -54.584 5.841 -63.016 1.00 46.76 ? 254 PHE A CA 1 +ATOM 1270 C C . PHE A 1 192 ? -53.221 5.174 -63.146 1.00 41.32 ? 254 PHE A C 1 +ATOM 1271 O O . PHE A 1 192 ? -53.150 3.942 -63.097 1.00 40.41 ? 254 PHE A O 1 +ATOM 1272 C CB . PHE A 1 192 ? -55.435 5.519 -64.258 1.00 45.32 ? 254 PHE A CB 1 +ATOM 1273 C CG . PHE A 1 192 ? -55.187 6.427 -65.436 1.00 49.27 ? 254 PHE A CG 1 +ATOM 1274 C CD1 . PHE A 1 192 ? -54.074 6.254 -66.245 1.00 48.75 ? 254 PHE A CD1 1 +ATOM 1275 C CD2 . PHE A 1 192 ? -56.095 7.423 -65.764 1.00 49.89 ? 254 PHE A CD2 1 +ATOM 1276 C CE1 . PHE A 1 192 ? -53.852 7.079 -67.335 1.00 49.83 ? 254 PHE A CE1 1 +ATOM 1277 C CE2 . PHE A 1 192 ? -55.880 8.252 -66.854 1.00 52.05 ? 254 PHE A CE2 1 +ATOM 1278 C CZ . PHE A 1 192 ? -54.760 8.078 -67.642 1.00 53.65 ? 254 PHE A CZ 1 +ATOM 1279 N N . ILE A 1 193 ? -52.140 5.938 -63.267 1.00 42.71 ? 255 ILE A N 1 +ATOM 1280 C CA . ILE A 1 193 ? -50.799 5.372 -63.287 1.00 48.14 ? 255 ILE A CA 1 +ATOM 1281 C C . ILE A 1 193 ? -50.014 5.759 -62.043 1.00 51.83 ? 255 ILE A C 1 +ATOM 1282 O O . ILE A 1 193 ? -48.806 5.512 -61.975 1.00 54.78 ? 255 ILE A O 1 +ATOM 1283 C CB . ILE A 1 193 ? -50.029 5.768 -64.557 1.00 52.07 ? 255 ILE A CB 1 +ATOM 1284 C CG1 . ILE A 1 193 ? -49.829 7.275 -64.605 1.00 59.46 ? 255 ILE A CG1 1 +ATOM 1285 C CG2 . ILE A 1 193 ? -50.775 5.322 -65.800 1.00 47.84 ? 255 ILE A CG2 1 +ATOM 1286 C CD1 . ILE A 1 193 ? -48.972 7.714 -65.759 1.00 65.87 ? 255 ILE A CD1 1 +ATOM 1287 N N . ASP A 1 194 ? -50.664 6.388 -61.066 1.00 48.01 ? 256 ASP A N 1 +ATOM 1288 C CA . ASP A 1 194 ? -50.006 6.701 -59.807 1.00 51.48 ? 256 ASP A CA 1 +ATOM 1289 C C . ASP A 1 194 ? -49.635 5.406 -59.078 1.00 55.45 ? 256 ASP A C 1 +ATOM 1290 O O . ASP A 1 194 ? -50.163 4.326 -59.362 1.00 57.63 ? 256 ASP A O 1 +ATOM 1291 C CB . ASP A 1 194 ? -50.915 7.587 -58.948 1.00 51.77 ? 256 ASP A CB 1 +ATOM 1292 C CG . ASP A 1 194 ? -50.148 8.410 -57.920 1.00 48.02 ? 256 ASP A CG 1 +ATOM 1293 O OD1 . ASP A 1 194 ? -48.933 8.177 -57.748 1.00 49.98 ? 256 ASP A OD1 1 +ATOM 1294 O OD2 . ASP A 1 194 ? -50.755 9.322 -57.316 1.00 38.15 ? 256 ASP A OD2 1 +ATOM 1295 N N . PHE A 1 195 ? -48.719 5.525 -58.122 1.00 54.22 ? 257 PHE A N 1 +ATOM 1296 C CA . PHE A 1 195 ? -48.164 4.364 -57.437 1.00 53.35 ? 257 PHE A CA 1 +ATOM 1297 C C . PHE A 1 195 ? -49.188 3.770 -56.464 1.00 60.09 ? 257 PHE A C 1 +ATOM 1298 O O . PHE A 1 195 ? -50.380 4.094 -56.477 1.00 55.60 ? 257 PHE A O 1 +ATOM 1299 C CB . PHE A 1 195 ? -46.879 4.743 -56.708 1.00 48.02 ? 257 PHE A CB 1 +ATOM 1300 C CG . PHE A 1 195 ? -45.664 4.777 -57.579 1.00 53.92 ? 257 PHE A CG 1 +ATOM 1301 C CD1 . PHE A 1 195 ? -44.903 3.639 -57.768 1.00 57.50 ? 257 PHE A CD1 1 +ATOM 1302 C CD2 . PHE A 1 195 ? -45.278 5.947 -58.203 1.00 65.65 ? 257 PHE A CD2 1 +ATOM 1303 C CE1 . PHE A 1 195 ? -43.772 3.667 -58.564 1.00 64.51 ? 257 PHE A CE1 1 +ATOM 1304 C CE2 . PHE A 1 195 ? -44.149 5.984 -59.004 1.00 64.37 ? 257 PHE A CE2 1 +ATOM 1305 C CZ . PHE A 1 195 ? -43.395 4.841 -59.184 1.00 62.30 ? 257 PHE A CZ 1 +ATOM 1306 N N . GLN A 1 196 ? -48.693 2.889 -55.580 1.00 59.29 ? 258 GLN A N 1 +ATOM 1307 C CA . GLN A 1 196 ? -49.488 2.119 -54.622 1.00 54.10 ? 258 GLN A CA 1 +ATOM 1308 C C . GLN A 1 196 ? -48.690 2.125 -53.316 1.00 54.13 ? 258 GLN A C 1 +ATOM 1309 O O . GLN A 1 196 ? -47.951 1.185 -53.014 1.00 59.17 ? 258 GLN A O 1 +ATOM 1310 C CB . GLN A 1 196 ? -49.737 0.698 -55.132 1.00 60.08 ? 258 GLN A CB 1 +ATOM 1311 C CG . GLN A 1 196 ? -51.068 0.087 -54.738 1.00 56.15 ? 258 GLN A CG 1 +ATOM 1312 C CD . GLN A 1 196 ? -52.004 -0.063 -55.920 1.00 54.70 ? 258 GLN A CD 1 +ATOM 1313 O OE1 . GLN A 1 196 ? -51.716 0.411 -57.020 1.00 52.18 ? 258 GLN A OE1 1 +ATOM 1314 N NE2 . GLN A 1 196 ? -53.129 -0.729 -55.701 1.00 57.21 ? 258 GLN A NE2 1 +ATOM 1315 N N . ARG A 1 197 ? -48.774 3.222 -52.568 1.00 50.83 ? 259 ARG A N 1 +ATOM 1316 C CA . ARG A 1 197 ? -47.917 3.382 -51.399 1.00 50.03 ? 259 ARG A CA 1 +ATOM 1317 C C . ARG A 1 197 ? -48.449 2.583 -50.219 1.00 51.23 ? 259 ARG A C 1 +ATOM 1318 O O . ARG A 1 197 ? -49.624 2.702 -49.849 1.00 47.69 ? 259 ARG A O 1 +ATOM 1319 C CB . ARG A 1 197 ? -47.781 4.853 -51.016 1.00 51.73 ? 259 ARG A CB 1 +ATOM 1320 C CG . ARG A 1 197 ? -48.452 5.806 -51.977 1.00 52.42 ? 259 ARG A CG 1 +ATOM 1321 C CD . ARG A 1 197 ? -47.706 7.125 -52.075 1.00 43.28 ? 259 ARG A CD 1 +ATOM 1322 N NE . ARG A 1 197 ? -47.347 7.398 -53.459 1.00 39.13 ? 259 ARG A NE 1 +ATOM 1323 C CZ . ARG A 1 197 ? -48.219 7.790 -54.381 1.00 42.00 ? 259 ARG A CZ 1 +ATOM 1324 N NH1 . ARG A 1 197 ? -49.495 7.957 -54.055 1.00 41.92 ? 259 ARG A NH1 1 +ATOM 1325 N NH2 . ARG A 1 197 ? -47.816 8.013 -55.625 1.00 43.41 ? 259 ARG A NH2 1 +ATOM 1326 N N . HIS A 1 198 ? -47.564 1.795 -49.603 1.00 47.43 ? 260 HIS A N 1 +ATOM 1327 C CA . HIS A 1 198 ? -47.962 1.048 -48.420 1.00 41.99 ? 260 HIS A CA 1 +ATOM 1328 C C . HIS A 1 198 ? -48.274 1.994 -47.276 1.00 42.19 ? 260 HIS A C 1 +ATOM 1329 O O . HIS A 1 198 ? -49.310 1.859 -46.617 1.00 48.59 ? 260 HIS A O 1 +ATOM 1330 C CB . HIS A 1 198 ? -46.865 0.057 -48.018 1.00 41.18 ? 260 HIS A CB 1 +ATOM 1331 C CG . HIS A 1 198 ? -45.568 0.697 -47.610 1.00 45.48 ? 260 HIS A CG 1 +ATOM 1332 N ND1 . HIS A 1 198 ? -44.986 1.732 -48.311 1.00 47.79 ? 260 HIS A ND1 1 +ATOM 1333 C CD2 . HIS A 1 198 ? -44.744 0.443 -46.565 1.00 46.21 ? 260 HIS A CD2 1 +ATOM 1334 C CE1 . HIS A 1 198 ? -43.859 2.085 -47.717 1.00 50.08 ? 260 HIS A CE1 1 +ATOM 1335 N NE2 . HIS A 1 198 ? -43.690 1.318 -46.655 1.00 45.90 ? 260 HIS A NE2 1 +ATOM 1336 N N . ASN A 1 199 ? -47.430 3.006 -47.083 1.00 40.28 ? 261 ASN A N 1 +ATOM 1337 C CA . ASN A 1 199 ? -47.614 3.916 -45.966 1.00 38.00 ? 261 ASN A CA 1 +ATOM 1338 C C . ASN A 1 199 ? -48.916 4.683 -46.074 1.00 38.00 ? 261 ASN A C 1 +ATOM 1339 O O . ASN A 1 199 ? -49.439 5.142 -45.054 1.00 44.06 ? 261 ASN A O 1 +ATOM 1340 C CB . ASN A 1 199 ? -46.438 4.873 -45.894 1.00 38.00 ? 261 ASN A CB 1 +ATOM 1341 C CG . ASN A 1 199 ? -46.306 5.688 -47.142 1.00 41.55 ? 261 ASN A CG 1 +ATOM 1342 O OD1 . ASN A 1 199 ? -45.752 5.228 -48.141 1.00 49.23 ? 261 ASN A OD1 1 +ATOM 1343 N ND2 . ASN A 1 199 ? -46.827 6.903 -47.108 1.00 51.14 ? 261 ASN A ND2 1 +ATOM 1344 N N . ALA A 1 200 ? -49.473 4.804 -47.275 1.00 38.00 ? 262 ALA A N 1 +ATOM 1345 C CA . ALA A 1 200 ? -50.765 5.461 -47.377 1.00 38.00 ? 262 ALA A CA 1 +ATOM 1346 C C . ALA A 1 200 ? -51.871 4.553 -46.865 1.00 38.00 ? 262 ALA A C 1 +ATOM 1347 O O . ALA A 1 200 ? -52.805 5.023 -46.211 1.00 38.00 ? 262 ALA A O 1 +ATOM 1348 C CB . ALA A 1 200 ? -51.036 5.884 -48.820 1.00 38.78 ? 262 ALA A CB 1 +ATOM 1349 N N . GLU A 1 201 ? -51.766 3.244 -47.126 1.00 38.12 ? 263 GLU A N 1 +ATOM 1350 C CA . GLU A 1 201 ? -52.744 2.301 -46.587 1.00 43.17 ? 263 GLU A CA 1 +ATOM 1351 C C . GLU A 1 201 ? -52.761 2.320 -45.067 1.00 41.10 ? 263 GLU A C 1 +ATOM 1352 O O . GLU A 1 201 ? -53.814 2.103 -44.456 1.00 40.28 ? 263 GLU A O 1 +ATOM 1353 C CB . GLU A 1 201 ? -52.469 0.884 -47.092 1.00 49.53 ? 263 GLU A CB 1 +ATOM 1354 C CG . GLU A 1 201 ? -52.854 0.649 -48.546 1.00 49.52 ? 263 GLU A CG 1 +ATOM 1355 C CD . GLU A 1 201 ? -54.336 0.326 -48.731 1.00 53.50 ? 263 GLU A CD 1 +ATOM 1356 O OE1 . GLU A 1 201 ? -54.947 -0.283 -47.826 1.00 57.91 ? 263 GLU A OE1 1 +ATOM 1357 O OE2 . GLU A 1 201 ? -54.890 0.688 -49.787 1.00 52.52 ? 263 GLU A OE2 1 +ATOM 1358 N N . ILE A 1 202 ? -51.603 2.536 -44.444 1.00 38.78 ? 264 ILE A N 1 +ATOM 1359 C CA . ILE A 1 202 ? -51.537 2.651 -42.990 1.00 38.00 ? 264 ILE A CA 1 +ATOM 1360 C C . ILE A 1 202 ? -52.170 3.955 -42.531 1.00 40.83 ? 264 ILE A C 1 +ATOM 1361 O O . ILE A 1 202 ? -53.118 3.966 -41.735 1.00 40.05 ? 264 ILE A O 1 +ATOM 1362 C CB . ILE A 1 202 ? -50.080 2.560 -42.516 1.00 38.00 ? 264 ILE A CB 1 +ATOM 1363 C CG1 . ILE A 1 202 ? -49.397 1.357 -43.148 1.00 38.00 ? 264 ILE A CG1 1 +ATOM 1364 C CG2 . ILE A 1 202 ? -50.019 2.513 -41.018 1.00 38.00 ? 264 ILE A CG2 1 +ATOM 1365 C CD1 . ILE A 1 202 ? -47.920 1.333 -42.900 1.00 38.00 ? 264 ILE A CD1 1 +ATOM 1366 N N . ALA A 1 203 ? -51.651 5.075 -43.039 1.00 40.71 ? 265 ALA A N 1 +ATOM 1367 C CA . ALA A 1 203 ? -52.126 6.384 -42.614 1.00 40.46 ? 265 ALA A CA 1 +ATOM 1368 C C . ALA A 1 203 ? -53.605 6.573 -42.909 1.00 38.00 ? 265 ALA A C 1 +ATOM 1369 O O . ALA A 1 203 ? -54.302 7.262 -42.157 1.00 38.00 ? 265 ALA A O 1 +ATOM 1370 C CB . ALA A 1 203 ? -51.299 7.476 -43.287 1.00 38.91 ? 265 ALA A CB 1 +ATOM 1371 N N . ALA A 1 204 ? -54.109 5.953 -43.976 1.00 38.00 ? 266 ALA A N 1 +ATOM 1372 C CA . ALA A 1 204 ? -55.537 6.036 -44.244 1.00 38.00 ? 266 ALA A CA 1 +ATOM 1373 C C . ALA A 1 204 ? -56.335 5.404 -43.124 1.00 38.00 ? 266 ALA A C 1 +ATOM 1374 O O . ALA A 1 204 ? -57.463 5.826 -42.848 1.00 39.23 ? 266 ALA A O 1 +ATOM 1375 C CB . ALA A 1 204 ? -55.879 5.357 -45.567 1.00 43.38 ? 266 ALA A CB 1 +ATOM 1376 N N . PHE A 1 205 ? -55.766 4.400 -42.462 1.00 38.00 ? 267 PHE A N 1 +ATOM 1377 C CA . PHE A 1 205 ? -56.466 3.787 -41.344 1.00 41.07 ? 267 PHE A CA 1 +ATOM 1378 C C . PHE A 1 205 ? -56.481 4.713 -40.138 1.00 45.20 ? 267 PHE A C 1 +ATOM 1379 O O . PHE A 1 205 ? -57.536 4.940 -39.535 1.00 49.76 ? 267 PHE A O 1 +ATOM 1380 C CB . PHE A 1 205 ? -55.832 2.443 -40.993 1.00 38.58 ? 267 PHE A CB 1 +ATOM 1381 C CG . PHE A 1 205 ? -56.272 1.901 -39.669 1.00 39.09 ? 267 PHE A CG 1 +ATOM 1382 C CD1 . PHE A 1 205 ? -57.617 1.678 -39.413 1.00 39.67 ? 267 PHE A CD1 1 +ATOM 1383 C CD2 . PHE A 1 205 ? -55.344 1.597 -38.689 1.00 38.00 ? 267 PHE A CD2 1 +ATOM 1384 C CE1 . PHE A 1 205 ? -58.031 1.182 -38.194 1.00 38.00 ? 267 PHE A CE1 1 +ATOM 1385 C CE2 . PHE A 1 205 ? -55.751 1.092 -37.470 1.00 39.19 ? 267 PHE A CE2 1 +ATOM 1386 C CZ . PHE A 1 205 ? -57.097 0.884 -37.223 1.00 40.90 ? 267 PHE A CZ 1 +ATOM 1387 N N . HIS A 1 206 ? -55.328 5.291 -39.796 1.00 41.30 ? 268 HIS A N 1 +ATOM 1388 C CA . HIS A 1 206 ? -55.273 6.167 -38.632 1.00 39.38 ? 268 HIS A CA 1 +ATOM 1389 C C . HIS A 1 206 ? -56.170 7.379 -38.807 1.00 42.80 ? 268 HIS A C 1 +ATOM 1390 O O . HIS A 1 206 ? -56.873 7.776 -37.870 1.00 44.27 ? 268 HIS A O 1 +ATOM 1391 C CB . HIS A 1 206 ? -53.835 6.583 -38.377 1.00 38.00 ? 268 HIS A CB 1 +ATOM 1392 C CG . HIS A 1 206 ? -52.976 5.448 -37.944 1.00 38.00 ? 268 HIS A CG 1 +ATOM 1393 N ND1 . HIS A 1 206 ? -52.525 5.313 -36.651 1.00 44.78 ? 268 HIS A ND1 1 +ATOM 1394 C CD2 . HIS A 1 206 ? -52.533 4.362 -38.615 1.00 40.02 ? 268 HIS A CD2 1 +ATOM 1395 C CE1 . HIS A 1 206 ? -51.811 4.205 -36.551 1.00 49.18 ? 268 HIS A CE1 1 +ATOM 1396 N NE2 . HIS A 1 206 ? -51.803 3.608 -37.729 1.00 48.38 ? 268 HIS A NE2 1 +ATOM 1397 N N . LEU A 1 207 ? -56.204 7.946 -40.015 1.00 43.38 ? 269 LEU A N 1 +ATOM 1398 C CA . LEU A 1 207 ? -57.116 9.053 -40.283 1.00 44.94 ? 269 LEU A CA 1 +ATOM 1399 C C . LEU A 1 207 ? -58.566 8.617 -40.128 1.00 41.92 ? 269 LEU A C 1 +ATOM 1400 O O . LEU A 1 207 ? -59.401 9.372 -39.616 1.00 41.19 ? 269 LEU A O 1 +ATOM 1401 C CB . LEU A 1 207 ? -56.867 9.599 -41.688 1.00 39.61 ? 269 LEU A CB 1 +ATOM 1402 C CG . LEU A 1 207 ? -56.852 11.115 -41.876 1.00 38.00 ? 269 LEU A CG 1 +ATOM 1403 C CD1 . LEU A 1 207 ? -56.790 11.437 -43.349 1.00 38.00 ? 269 LEU A CD1 1 +ATOM 1404 C CD2 . LEU A 1 207 ? -58.058 11.766 -41.243 1.00 38.00 ? 269 LEU A CD2 1 +ATOM 1405 N N . ASP A 1 208 ? -58.882 7.394 -40.554 1.00 41.52 ? 270 ASP A N 1 +ATOM 1406 C CA . ASP A 1 208 ? -60.217 6.859 -40.328 1.00 40.68 ? 270 ASP A CA 1 +ATOM 1407 C C . ASP A 1 208 ? -60.519 6.760 -38.841 1.00 41.59 ? 270 ASP A C 1 +ATOM 1408 O O . ASP A 1 208 ? -61.648 7.015 -38.406 1.00 38.41 ? 270 ASP A O 1 +ATOM 1409 C CB . ASP A 1 208 ? -60.350 5.495 -41.000 1.00 41.94 ? 270 ASP A CB 1 +ATOM 1410 C CG . ASP A 1 208 ? -61.724 4.887 -40.812 1.00 52.10 ? 270 ASP A CG 1 +ATOM 1411 O OD1 . ASP A 1 208 ? -62.669 5.621 -40.445 1.00 48.70 ? 270 ASP A OD1 1 +ATOM 1412 O OD2 . ASP A 1 208 ? -61.859 3.666 -41.031 1.00 55.82 ? 270 ASP A OD2 1 +ATOM 1413 N N . ARG A 1 209 ? -59.523 6.369 -38.049 1.00 42.74 ? 271 ARG A N 1 +ATOM 1414 C CA . ARG A 1 209 ? -59.740 6.221 -36.618 1.00 41.56 ? 271 ARG A CA 1 +ATOM 1415 C C . ARG A 1 209 ? -59.891 7.577 -35.941 1.00 41.95 ? 271 ARG A C 1 +ATOM 1416 O O . ARG A 1 209 ? -60.736 7.743 -35.053 1.00 45.18 ? 271 ARG A O 1 +ATOM 1417 C CB . ARG A 1 209 ? -58.587 5.424 -36.008 1.00 38.00 ? 271 ARG A CB 1 +ATOM 1418 C CG . ARG A 1 209 ? -58.908 4.835 -34.661 1.00 38.00 ? 271 ARG A CG 1 +ATOM 1419 C CD . ARG A 1 209 ? -57.917 3.765 -34.248 1.00 38.20 ? 271 ARG A CD 1 +ATOM 1420 N NE . ARG A 1 209 ? -56.532 4.162 -34.483 1.00 44.11 ? 271 ARG A NE 1 +ATOM 1421 C CZ . ARG A 1 209 ? -55.485 3.355 -34.320 1.00 47.50 ? 271 ARG A CZ 1 +ATOM 1422 N NH1 . ARG A 1 209 ? -55.659 2.102 -33.917 1.00 45.16 ? 271 ARG A NH1 1 +ATOM 1423 N NH2 . ARG A 1 209 ? -54.259 3.802 -34.555 1.00 44.51 ? 271 ARG A NH2 1 +ATOM 1424 N N . ILE A 1 210 ? -59.114 8.568 -36.380 1.00 38.84 ? 272 ILE A N 1 +ATOM 1425 C CA . ILE A 1 210 ? -59.150 9.883 -35.750 1.00 38.00 ? 272 ILE A CA 1 +ATOM 1426 C C . ILE A 1 210 ? -60.460 10.597 -36.069 1.00 38.00 ? 272 ILE A C 1 +ATOM 1427 O O . ILE A 1 210 ? -61.021 11.297 -35.218 1.00 43.62 ? 272 ILE A O 1 +ATOM 1428 C CB . ILE A 1 210 ? -57.922 10.709 -36.180 1.00 38.00 ? 272 ILE A CB 1 +ATOM 1429 C CG1 . ILE A 1 210 ? -56.770 10.555 -35.181 1.00 38.00 ? 272 ILE A CG1 1 +ATOM 1430 C CG2 . ILE A 1 210 ? -58.276 12.175 -36.324 1.00 40.07 ? 272 ILE A CG2 1 +ATOM 1431 C CD1 . ILE A 1 210 ? -56.179 9.165 -35.101 1.00 38.55 ? 272 ILE A CD1 1 +ATOM 1432 N N . LEU A 1 211 ? -60.968 10.437 -37.295 1.00 38.00 ? 273 LEU A N 1 +ATOM 1433 C CA . LEU A 1 211 ? -62.227 11.073 -37.681 1.00 38.51 ? 273 LEU A CA 1 +ATOM 1434 C C . LEU A 1 211 ? -63.450 10.400 -37.079 1.00 39.54 ? 273 LEU A C 1 +ATOM 1435 O O . LEU A 1 211 ? -64.555 10.941 -37.204 1.00 38.00 ? 273 LEU A O 1 +ATOM 1436 C CB . LEU A 1 211 ? -62.387 11.090 -39.199 1.00 38.09 ? 273 LEU A CB 1 +ATOM 1437 C CG . LEU A 1 211 ? -61.507 12.026 -40.017 1.00 38.00 ? 273 LEU A CG 1 +ATOM 1438 C CD1 . LEU A 1 211 ? -61.753 11.763 -41.485 1.00 42.30 ? 273 LEU A CD1 1 +ATOM 1439 C CD2 . LEU A 1 211 ? -61.803 13.469 -39.674 1.00 38.00 ? 273 LEU A CD2 1 +ATOM 1440 N N . ASP A 1 212 ? -63.290 9.232 -36.465 1.00 40.43 ? 274 ASP A N 1 +ATOM 1441 C CA . ASP A 1 212 ? -64.417 8.435 -35.994 1.00 43.73 ? 274 ASP A CA 1 +ATOM 1442 C C . ASP A 1 212 ? -65.389 8.121 -37.132 1.00 49.54 ? 274 ASP A C 1 +ATOM 1443 O O . ASP A 1 212 ? -66.608 8.106 -36.939 1.00 48.01 ? 274 ASP A O 1 +ATOM 1444 C CB . ASP A 1 212 ? -65.137 9.115 -34.829 1.00 45.69 ? 274 ASP A CB 1 +ATOM 1445 C CG . ASP A 1 212 ? -65.978 8.150 -34.035 1.00 51.08 ? 274 ASP A CG 1 +ATOM 1446 O OD1 . ASP A 1 212 ? -65.454 7.068 -33.696 1.00 47.34 ? 274 ASP A OD1 1 +ATOM 1447 O OD2 . ASP A 1 212 ? -67.154 8.467 -33.756 1.00 57.45 ? 274 ASP A OD2 1 +ATOM 1448 N N . PHE A 1 213 ? -64.854 7.962 -38.347 1.00 47.55 ? 275 PHE A N 1 +ATOM 1449 C CA . PHE A 1 213 ? -65.635 7.402 -39.446 1.00 48.88 ? 275 PHE A CA 1 +ATOM 1450 C C . PHE A 1 213 ? -65.786 5.896 -39.294 1.00 49.62 ? 275 PHE A C 1 +ATOM 1451 O O . PHE A 1 213 ? -66.877 5.350 -39.506 1.00 46.08 ? 275 PHE A O 1 +ATOM 1452 C CB . PHE A 1 213 ? -64.979 7.734 -40.780 1.00 54.24 ? 275 PHE A CB 1 +ATOM 1453 C CG . PHE A 1 213 ? -65.334 9.087 -41.307 1.00 57.46 ? 275 PHE A CG 1 +ATOM 1454 C CD1 . PHE A 1 213 ? -66.412 9.787 -40.792 1.00 57.87 ? 275 PHE A CD1 1 +ATOM 1455 C CD2 . PHE A 1 213 ? -64.580 9.665 -42.311 1.00 49.35 ? 275 PHE A CD2 1 +ATOM 1456 C CE1 . PHE A 1 213 ? -66.736 11.034 -41.282 1.00 59.09 ? 275 PHE A CE1 1 +ATOM 1457 C CE2 . PHE A 1 213 ? -64.896 10.909 -42.802 1.00 54.07 ? 275 PHE A CE2 1 +ATOM 1458 C CZ . PHE A 1 213 ? -65.977 11.597 -42.287 1.00 64.01 ? 275 PHE A CZ 1 +ATOM 1459 N N . ARG A 1 214 ? -64.691 5.212 -38.946 1.00 47.72 ? 276 ARG A N 1 +ATOM 1460 C CA . ARG A 1 214 ? -64.705 3.781 -38.640 1.00 47.08 ? 276 ARG A CA 1 +ATOM 1461 C C . ARG A 1 214 ? -65.227 2.974 -39.825 1.00 50.31 ? 276 ARG A C 1 +ATOM 1462 O O . ARG A 1 214 ? -66.249 2.290 -39.745 1.00 53.16 ? 276 ARG A O 1 +ATOM 1463 C CB . ARG A 1 214 ? -65.528 3.533 -37.367 1.00 49.56 ? 276 ARG A CB 1 +ATOM 1464 C CG . ARG A 1 214 ? -64.691 3.223 -36.131 1.00 46.40 ? 276 ARG A CG 1 +ATOM 1465 C CD . ARG A 1 214 ? -65.316 3.683 -34.821 1.00 44.32 ? 276 ARG A CD 1 +ATOM 1466 N NE . ARG A 1 214 ? -66.721 3.312 -34.684 1.00 49.16 ? 276 ARG A NE 1 +ATOM 1467 C CZ . ARG A 1 214 ? -67.691 4.222 -34.703 1.00 52.81 ? 276 ARG A CZ 1 +ATOM 1468 N NH1 . ARG A 1 214 ? -67.360 5.505 -34.816 1.00 51.23 ? 276 ARG A NH1 1 +ATOM 1469 N NH2 . ARG A 1 214 ? -68.970 3.873 -34.585 1.00 63.28 ? 276 ARG A NH2 1 +ATOM 1470 N N . ARG A 1 215 ? -64.496 3.077 -40.941 1.00 50.42 ? 277 ARG A N 1 +ATOM 1471 C CA . ARG A 1 215 ? -64.923 2.506 -42.217 1.00 46.66 ? 277 ARG A CA 1 +ATOM 1472 C C . ARG A 1 215 ? -63.824 1.797 -42.998 1.00 43.99 ? 277 ARG A C 1 +ATOM 1473 O O . ARG A 1 215 ? -64.146 0.960 -43.846 1.00 47.87 ? 277 ARG A O 1 +ATOM 1474 C CB . ARG A 1 215 ? -65.542 3.593 -43.096 1.00 45.10 ? 277 ARG A CB 1 +ATOM 1475 C CG . ARG A 1 215 ? -66.843 4.111 -42.533 1.00 47.45 ? 277 ARG A CG 1 +ATOM 1476 C CD . ARG A 1 215 ? -67.300 5.348 -43.243 1.00 54.31 ? 277 ARG A CD 1 +ATOM 1477 N NE . ARG A 1 215 ? -68.048 6.231 -42.356 1.00 58.48 ? 277 ARG A NE 1 +ATOM 1478 C CZ . ARG A 1 215 ? -68.709 7.300 -42.780 1.00 65.83 ? 277 ARG A CZ 1 +ATOM 1479 N NH1 . ARG A 1 215 ? -68.711 7.594 -44.075 1.00 77.45 ? 277 ARG A NH1 1 +ATOM 1480 N NH2 . ARG A 1 215 ? -69.367 8.067 -41.921 1.00 55.61 ? 277 ARG A NH2 1 +ATOM 1481 N N . VAL A 1 216 ? -62.553 2.110 -42.794 1.00 41.50 ? 278 VAL A N 1 +ATOM 1482 C CA . VAL A 1 216 ? -61.503 1.365 -43.480 1.00 43.87 ? 278 VAL A CA 1 +ATOM 1483 C C . VAL A 1 216 ? -61.039 0.225 -42.580 1.00 47.16 ? 278 VAL A C 1 +ATOM 1484 O O . VAL A 1 216 ? -61.163 0.317 -41.349 1.00 44.20 ? 278 VAL A O 1 +ATOM 1485 C CB . VAL A 1 216 ? -60.339 2.281 -43.885 1.00 46.37 ? 278 VAL A CB 1 +ATOM 1486 C CG1 . VAL A 1 216 ? -60.862 3.657 -44.196 1.00 52.75 ? 278 VAL A CG1 1 +ATOM 1487 C CG2 . VAL A 1 216 ? -59.303 2.340 -42.788 1.00 45.77 ? 278 VAL A CG2 1 +ATOM 1488 N N . PRO A 1 217 ? -60.538 -0.879 -43.138 1.00 47.33 ? 279 PRO A N 1 +ATOM 1489 C CA . PRO A 1 217 ? -60.080 -1.972 -42.291 1.00 41.20 ? 279 PRO A CA 1 +ATOM 1490 C C . PRO A 1 217 ? -58.781 -1.606 -41.594 1.00 38.16 ? 279 PRO A C 1 +ATOM 1491 O O . PRO A 1 217 ? -57.926 -0.912 -42.169 1.00 38.00 ? 279 PRO A O 1 +ATOM 1492 C CB . PRO A 1 217 ? -59.868 -3.127 -43.285 1.00 42.66 ? 279 PRO A CB 1 +ATOM 1493 C CG . PRO A 1 217 ? -60.622 -2.739 -44.499 1.00 47.47 ? 279 PRO A CG 1 +ATOM 1494 C CD . PRO A 1 217 ? -60.520 -1.253 -44.559 1.00 47.05 ? 279 PRO A CD 1 +ATOM 1495 N N . PRO A 1 218 ? -58.570 -2.099 -40.378 1.00 38.00 ? 280 PRO A N 1 +ATOM 1496 C CA . PRO A 1 218 ? -57.318 -1.818 -39.671 1.00 38.00 ? 280 PRO A CA 1 +ATOM 1497 C C . PRO A 1 218 ? -56.116 -2.251 -40.491 1.00 38.00 ? 280 PRO A C 1 +ATOM 1498 O O . PRO A 1 218 ? -56.146 -3.270 -41.179 1.00 42.57 ? 280 PRO A O 1 +ATOM 1499 C CB . PRO A 1 218 ? -57.452 -2.639 -38.385 1.00 38.00 ? 280 PRO A CB 1 +ATOM 1500 C CG . PRO A 1 218 ? -58.932 -2.765 -38.189 1.00 38.00 ? 280 PRO A CG 1 +ATOM 1501 C CD . PRO A 1 218 ? -59.516 -2.868 -39.553 1.00 38.00 ? 280 PRO A CD 1 +ATOM 1502 N N . THR A 1 219 ? -55.065 -1.441 -40.440 1.00 38.00 ? 281 THR A N 1 +ATOM 1503 C CA . THR A 1 219 ? -53.888 -1.668 -41.262 1.00 38.00 ? 281 THR A CA 1 +ATOM 1504 C C . THR A 1 219 ? -52.641 -1.331 -40.461 1.00 38.00 ? 281 THR A C 1 +ATOM 1505 O O . THR A 1 219 ? -52.591 -0.287 -39.806 1.00 41.01 ? 281 THR A O 1 +ATOM 1506 C CB . THR A 1 219 ? -53.956 -0.821 -42.537 1.00 38.00 ? 281 THR A CB 1 +ATOM 1507 O OG1 . THR A 1 219 ? -55.172 -1.109 -43.243 1.00 38.00 ? 281 THR A OG1 1 +ATOM 1508 C CG2 . THR A 1 219 ? -52.779 -1.120 -43.435 1.00 43.52 ? 281 THR A CG2 1 +ATOM 1509 N N . VAL A 1 220 ? -51.655 -2.223 -40.484 1.00 38.00 ? 282 VAL A N 1 +ATOM 1510 C CA . VAL A 1 220 ? -50.391 -1.993 -39.802 1.00 38.00 ? 282 VAL A CA 1 +ATOM 1511 C C . VAL A 1 220 ? -49.268 -2.121 -40.819 1.00 38.00 ? 282 VAL A C 1 +ATOM 1512 O O . VAL A 1 220 ? -49.426 -2.712 -41.889 1.00 38.00 ? 282 VAL A O 1 +ATOM 1513 C CB . VAL A 1 220 ? -50.163 -2.955 -38.614 1.00 38.00 ? 282 VAL A CB 1 +ATOM 1514 C CG1 . VAL A 1 220 ? -51.444 -3.634 -38.238 1.00 38.00 ? 282 VAL A CG1 1 +ATOM 1515 C CG2 . VAL A 1 220 ? -49.115 -4.001 -38.942 1.00 38.00 ? 282 VAL A CG2 1 +ATOM 1516 N N . GLY A 1 221 ? -48.131 -1.527 -40.483 1.00 41.85 ? 283 GLY A N 1 +ATOM 1517 C CA . GLY A 1 221 ? -46.908 -1.711 -41.235 1.00 39.33 ? 283 GLY A CA 1 +ATOM 1518 C C . GLY A 1 221 ? -46.039 -2.771 -40.586 1.00 44.97 ? 283 GLY A C 1 +ATOM 1519 O O . GLY A 1 221 ? -46.034 -2.928 -39.369 1.00 52.66 ? 283 GLY A O 1 +ATOM 1520 N N . ARG A 1 222 ? -45.306 -3.510 -41.414 1.00 42.18 ? 284 ARG A N 1 +ATOM 1521 C CA . ARG A 1 222 ? -44.488 -4.606 -40.919 1.00 40.97 ? 284 ARG A CA 1 +ATOM 1522 C C . ARG A 1 222 ? -43.327 -4.836 -41.871 1.00 39.94 ? 284 ARG A C 1 +ATOM 1523 O O . ARG A 1 222 ? -43.479 -4.708 -43.087 1.00 40.34 ? 284 ARG A O 1 +ATOM 1524 C CB . ARG A 1 222 ? -45.320 -5.884 -40.770 1.00 38.00 ? 284 ARG A CB 1 +ATOM 1525 C CG . ARG A 1 222 ? -44.517 -7.153 -40.559 1.00 41.36 ? 284 ARG A CG 1 +ATOM 1526 C CD . ARG A 1 222 ? -45.444 -8.312 -40.248 1.00 43.71 ? 284 ARG A CD 1 +ATOM 1527 N NE . ARG A 1 222 ? -44.726 -9.567 -40.061 1.00 40.00 ? 284 ARG A NE 1 +ATOM 1528 C CZ . ARG A 1 222 ? -45.315 -10.714 -39.746 1.00 43.20 ? 284 ARG A CZ 1 +ATOM 1529 N NH1 . ARG A 1 222 ? -46.631 -10.765 -39.581 1.00 38.00 ? 284 ARG A NH1 1 +ATOM 1530 N NH2 . ARG A 1 222 ? -44.590 -11.813 -39.598 1.00 50.63 ? 284 ARG A NH2 1 +ATOM 1531 N N . ILE A 1 223 ? -42.167 -5.143 -41.311 1.00 39.07 ? 285 ILE A N 1 +ATOM 1532 C CA . ILE A 1 223 ? -41.014 -5.557 -42.096 1.00 38.00 ? 285 ILE A CA 1 +ATOM 1533 C C . ILE A 1 223 ? -41.105 -7.059 -42.322 1.00 43.15 ? 285 ILE A C 1 +ATOM 1534 O O . ILE A 1 223 ? -41.293 -7.826 -41.371 1.00 55.09 ? 285 ILE A O 1 +ATOM 1535 C CB . ILE A 1 223 ? -39.706 -5.192 -41.388 1.00 38.16 ? 285 ILE A CB 1 +ATOM 1536 C CG1 . ILE A 1 223 ? -39.649 -3.689 -41.121 1.00 41.68 ? 285 ILE A CG1 1 +ATOM 1537 C CG2 . ILE A 1 223 ? -38.522 -5.685 -42.207 1.00 43.01 ? 285 ILE A CG2 1 +ATOM 1538 C CD1 . ILE A 1 223 ? -38.404 -3.254 -40.384 1.00 47.42 ? 285 ILE A CD1 1 +ATOM 1539 N N . VAL A 1 224 ? -40.982 -7.482 -43.577 1.00 38.83 ? 286 VAL A N 1 +ATOM 1540 C CA . VAL A 1 224 ? -41.213 -8.867 -43.971 1.00 41.21 ? 286 VAL A CA 1 +ATOM 1541 C C . VAL A 1 224 ? -39.912 -9.454 -44.514 1.00 43.94 ? 286 VAL A C 1 +ATOM 1542 O O . VAL A 1 224 ? -39.181 -8.774 -45.242 1.00 44.24 ? 286 VAL A O 1 +ATOM 1543 C CB . VAL A 1 224 ? -42.349 -8.971 -45.009 1.00 38.00 ? 286 VAL A CB 1 +ATOM 1544 C CG1 . VAL A 1 224 ? -42.630 -10.419 -45.345 1.00 38.00 ? 286 VAL A CG1 1 +ATOM 1545 C CG2 . VAL A 1 224 ? -43.616 -8.302 -44.490 1.00 38.00 ? 286 VAL A CG2 1 +ATOM 1546 N N . ASN A 1 225 ? -39.580 -10.677 -44.082 1.00 48.11 ? 287 ASN A N 1 +ATOM 1547 C CA . ASN A 1 225 ? -38.542 -11.495 -44.722 1.00 45.39 ? 287 ASN A CA 1 +ATOM 1548 C C . ASN A 1 225 ? -39.201 -12.198 -45.904 1.00 47.72 ? 287 ASN A C 1 +ATOM 1549 O O . ASN A 1 225 ? -39.841 -13.241 -45.742 1.00 46.80 ? 287 ASN A O 1 +ATOM 1550 C CB . ASN A 1 225 ? -37.926 -12.491 -43.736 1.00 45.35 ? 287 ASN A CB 1 +ATOM 1551 C CG . ASN A 1 225 ? -36.699 -13.220 -44.305 1.00 42.24 ? 287 ASN A CG 1 +ATOM 1552 O OD1 . ASN A 1 225 ? -36.597 -13.429 -45.507 1.00 44.45 ? 287 ASN A OD1 1 +ATOM 1553 N ND2 . ASN A 1 225 ? -35.767 -13.603 -43.433 1.00 38.00 ? 287 ASN A ND2 1 +ATOM 1554 N N . VAL A 1 226 ? -39.036 -11.624 -47.102 1.00 53.35 ? 288 VAL A N 1 +ATOM 1555 C CA . VAL A 1 226 ? -39.765 -12.078 -48.285 1.00 52.35 ? 288 VAL A CA 1 +ATOM 1556 C C . VAL A 1 226 ? -39.460 -13.526 -48.633 1.00 52.90 ? 288 VAL A C 1 +ATOM 1557 O O . VAL A 1 226 ? -40.280 -14.198 -49.267 1.00 51.19 ? 288 VAL A O 1 +ATOM 1558 C CB . VAL A 1 226 ? -39.465 -11.158 -49.487 1.00 44.75 ? 288 VAL A CB 1 +ATOM 1559 C CG1 . VAL A 1 226 ? -40.054 -9.786 -49.257 1.00 44.58 ? 288 VAL A CG1 1 +ATOM 1560 C CG2 . VAL A 1 226 ? -37.967 -11.065 -49.720 1.00 40.84 ? 288 VAL A CG2 1 +ATOM 1561 N N . THR A 1 227 ? -38.311 -14.040 -48.210 1.00 48.93 ? 289 THR A N 1 +ATOM 1562 C CA . THR A 1 227 ? -38.037 -15.447 -48.455 1.00 46.89 ? 289 THR A CA 1 +ATOM 1563 C C . THR A 1 227 ? -38.754 -16.324 -47.436 1.00 52.08 ? 289 THR A C 1 +ATOM 1564 O O . THR A 1 227 ? -39.524 -17.215 -47.809 1.00 50.53 ? 289 THR A O 1 +ATOM 1565 C CB . THR A 1 227 ? -36.531 -15.699 -48.425 1.00 44.22 ? 289 THR A CB 1 +ATOM 1566 O OG1 . THR A 1 227 ? -35.896 -14.901 -49.429 1.00 39.27 ? 289 THR A OG1 1 +ATOM 1567 C CG2 . THR A 1 227 ? -36.235 -17.165 -48.685 1.00 50.14 ? 289 THR A CG2 1 +ATOM 1568 N N . LYS A 1 228 ? -38.549 -16.053 -46.142 1.00 53.71 ? 290 LYS A N 1 +ATOM 1569 C CA . LYS A 1 228 ? -39.086 -16.923 -45.100 1.00 53.53 ? 290 LYS A CA 1 +ATOM 1570 C C . LYS A 1 228 ? -40.585 -16.726 -44.882 1.00 51.66 ? 290 LYS A C 1 +ATOM 1571 O O . LYS A 1 228 ? -41.276 -17.667 -44.472 1.00 52.14 ? 290 LYS A O 1 +ATOM 1572 C CB . LYS A 1 228 ? -38.326 -16.708 -43.784 1.00 47.03 ? 290 LYS A CB 1 +ATOM 1573 C CG . LYS A 1 228 ? -38.735 -17.684 -42.677 1.00 45.90 ? 290 LYS A CG 1 +ATOM 1574 C CD . LYS A 1 228 ? -38.059 -17.400 -41.344 1.00 38.00 ? 290 LYS A CD 1 +ATOM 1575 C CE . LYS A 1 228 ? -38.634 -16.159 -40.683 1.00 46.13 ? 290 LYS A CE 1 +ATOM 1576 N NZ . LYS A 1 228 ? -37.843 -15.710 -39.502 1.00 38.00 ? 290 LYS A NZ 1 +ATOM 1577 N N . GLU A 1 229 ? -41.105 -15.528 -45.138 1.00 44.74 ? 291 GLU A N 1 +ATOM 1578 C CA . GLU A 1 229 ? -42.485 -15.206 -44.812 1.00 41.92 ? 291 GLU A CA 1 +ATOM 1579 C C . GLU A 1 229 ? -43.387 -15.074 -46.029 1.00 39.34 ? 291 GLU A C 1 +ATOM 1580 O O . GLU A 1 229 ? -44.586 -14.835 -45.859 1.00 39.07 ? 291 GLU A O 1 +ATOM 1581 C CB . GLU A 1 229 ? -42.540 -13.923 -43.974 1.00 44.53 ? 291 GLU A CB 1 +ATOM 1582 C CG . GLU A 1 229 ? -42.284 -14.165 -42.493 1.00 47.35 ? 291 GLU A CG 1 +ATOM 1583 C CD . GLU A 1 229 ? -41.874 -12.913 -41.753 1.00 43.08 ? 291 GLU A CD 1 +ATOM 1584 O OE1 . GLU A 1 229 ? -41.529 -11.917 -42.413 1.00 45.91 ? 291 GLU A OE1 1 +ATOM 1585 O OE2 . GLU A 1 229 ? -41.894 -12.921 -40.508 1.00 51.20 ? 291 GLU A OE2 1 +ATOM 1586 N N . ILE A 1 230 ? -42.852 -15.199 -47.245 1.00 41.56 ? 292 ILE A N 1 +ATOM 1587 C CA . ILE A 1 230 ? -43.680 -15.158 -48.450 1.00 48.18 ? 292 ILE A CA 1 +ATOM 1588 C C . ILE A 1 230 ? -43.375 -16.342 -49.359 1.00 47.04 ? 292 ILE A C 1 +ATOM 1589 O O . ILE A 1 230 ? -44.267 -17.130 -49.699 1.00 44.87 ? 292 ILE A O 1 +ATOM 1590 C CB . ILE A 1 230 ? -43.490 -13.847 -49.229 1.00 44.22 ? 292 ILE A CB 1 +ATOM 1591 C CG1 . ILE A 1 230 ? -43.927 -12.648 -48.392 1.00 42.25 ? 292 ILE A CG1 1 +ATOM 1592 C CG2 . ILE A 1 230 ? -44.303 -13.896 -50.509 1.00 39.58 ? 292 ILE A CG2 1 +ATOM 1593 C CD1 . ILE A 1 230 ? -43.739 -11.330 -49.105 1.00 38.00 ? 292 ILE A CD1 1 +ATOM 1594 N N . LEU A 1 231 ? -42.121 -16.441 -49.802 1.00 43.54 ? 293 LEU A N 1 +ATOM 1595 C CA . LEU A 1 231 ? -41.758 -17.463 -50.776 1.00 41.70 ? 293 LEU A CA 1 +ATOM 1596 C C . LEU A 1 231 ? -41.833 -18.856 -50.168 1.00 48.00 ? 293 LEU A C 1 +ATOM 1597 O O . LEU A 1 231 ? -42.404 -19.774 -50.765 1.00 51.31 ? 293 LEU A O 1 +ATOM 1598 C CB . LEU A 1 231 ? -40.358 -17.187 -51.323 1.00 43.12 ? 293 LEU A CB 1 +ATOM 1599 C CG . LEU A 1 231 ? -39.784 -18.256 -52.250 1.00 42.24 ? 293 LEU A CG 1 +ATOM 1600 C CD1 . LEU A 1 231 ? -40.704 -18.450 -53.437 1.00 45.15 ? 293 LEU A CD1 1 +ATOM 1601 C CD2 . LEU A 1 231 ? -38.384 -17.866 -52.709 1.00 42.72 ? 293 LEU A CD2 1 +ATOM 1602 N N . GLU A 1 232 ? -41.275 -19.034 -48.974 1.00 49.55 ? 294 GLU A N 1 +ATOM 1603 C CA . GLU A 1 232 ? -41.212 -20.358 -48.370 1.00 47.24 ? 294 GLU A CA 1 +ATOM 1604 C C . GLU A 1 232 ? -42.545 -20.828 -47.810 1.00 43.42 ? 294 GLU A C 1 +ATOM 1605 O O . GLU A 1 232 ? -42.608 -21.937 -47.274 1.00 56.85 ? 294 GLU A O 1 +ATOM 1606 C CB . GLU A 1 232 ? -40.150 -20.387 -47.269 1.00 47.45 ? 294 GLU A CB 1 +ATOM 1607 C CG . GLU A 1 232 ? -38.729 -20.324 -47.800 1.00 52.05 ? 294 GLU A CG 1 +ATOM 1608 C CD . GLU A 1 232 ? -37.687 -20.447 -46.703 1.00 59.27 ? 294 GLU A CD 1 +ATOM 1609 O OE1 . GLU A 1 232 ? -38.042 -20.867 -45.575 1.00 55.99 ? 294 GLU A OE1 1 +ATOM 1610 O OE2 . GLU A 1 232 ? -36.509 -20.132 -46.976 1.00 58.41 ? 294 GLU A OE2 1 +ATOM 1611 N N . VAL A 1 233 ? -43.607 -20.037 -47.929 1.00 38.00 ? 295 VAL A N 1 +ATOM 1612 C CA . VAL A 1 233 ? -44.918 -20.429 -47.435 1.00 44.78 ? 295 VAL A CA 1 +ATOM 1613 C C . VAL A 1 233 ? -45.969 -20.464 -48.528 1.00 47.29 ? 295 VAL A C 1 +ATOM 1614 O O . VAL A 1 233 ? -47.116 -20.837 -48.256 1.00 47.95 ? 295 VAL A O 1 +ATOM 1615 C CB . VAL A 1 233 ? -45.376 -19.514 -46.281 1.00 43.56 ? 295 VAL A CB 1 +ATOM 1616 C CG1 . VAL A 1 233 ? -45.240 -20.236 -44.958 1.00 46.14 ? 295 VAL A CG1 1 +ATOM 1617 C CG2 . VAL A 1 233 ? -44.551 -18.258 -46.268 1.00 44.54 ? 295 VAL A CG2 1 +ATOM 1618 N N . THR A 1 234 ? -45.623 -20.086 -49.753 1.00 47.71 ? 296 THR A N 1 +ATOM 1619 C CA . THR A 1 234 ? -46.594 -20.076 -50.836 1.00 49.01 ? 296 THR A CA 1 +ATOM 1620 C C . THR A 1 234 ? -46.665 -21.429 -51.533 1.00 52.23 ? 296 THR A C 1 +ATOM 1621 O O . THR A 1 234 ? -45.641 -22.038 -51.856 1.00 53.88 ? 296 THR A O 1 +ATOM 1622 C CB . THR A 1 234 ? -46.265 -18.979 -51.852 1.00 46.29 ? 296 THR A CB 1 +ATOM 1623 O OG1 . THR A 1 234 ? -47.226 -19.018 -52.911 1.00 51.63 ? 296 THR A OG1 1 +ATOM 1624 C CG2 . THR A 1 234 ? -44.875 -19.158 -52.428 1.00 45.35 ? 296 THR A CG2 1 +ATOM 1625 N N . LYS A 1 235 ? -47.893 -21.888 -51.769 1.00 57.05 ? 297 LYS A N 1 +ATOM 1626 C CA . LYS A 1 235 ? -48.151 -23.100 -52.533 1.00 64.85 ? 297 LYS A CA 1 +ATOM 1627 C C . LYS A 1 235 ? -48.484 -22.819 -53.992 1.00 59.04 ? 297 LYS A C 1 +ATOM 1628 O O . LYS A 1 235 ? -48.718 -23.763 -54.754 1.00 55.50 ? 297 LYS A O 1 +ATOM 1629 C CB . LYS A 1 235 ? -49.285 -23.906 -51.884 1.00 72.77 ? 297 LYS A CB 1 +ATOM 1630 C CG . LYS A 1 235 ? -48.999 -24.363 -50.457 1.00 80.50 ? 297 LYS A CG 1 +ATOM 1631 C CD . LYS A 1 235 ? -47.848 -25.368 -50.449 1.00 76.61 ? 297 LYS A CD 1 +ATOM 1632 C CE . LYS A 1 235 ? -47.543 -25.887 -49.057 1.00 79.05 ? 297 LYS A CE 1 +ATOM 1633 N NZ . LYS A 1 235 ? -46.510 -26.962 -49.114 1.00 66.79 ? 297 LYS A NZ 1 +ATOM 1634 N N . ASN A 1 236 ? -48.509 -21.549 -54.396 1.00 63.34 ? 298 ASN A N 1 +ATOM 1635 C CA . ASN A 1 236 ? -48.876 -21.174 -55.756 1.00 57.60 ? 298 ASN A CA 1 +ATOM 1636 C C . ASN A 1 236 ? -47.649 -21.284 -56.652 1.00 52.47 ? 298 ASN A C 1 +ATOM 1637 O O . ASN A 1 236 ? -46.628 -20.632 -56.407 1.00 44.03 ? 298 ASN A O 1 +ATOM 1638 C CB . ASN A 1 236 ? -49.455 -19.760 -55.779 1.00 47.19 ? 298 ASN A CB 1 +ATOM 1639 C CG . ASN A 1 236 ? -50.058 -19.393 -57.118 1.00 42.45 ? 298 ASN A CG 1 +ATOM 1640 O OD1 . ASN A 1 236 ? -49.339 -19.068 -58.063 1.00 43.13 ? 298 ASN A OD1 1 +ATOM 1641 N ND2 . ASN A 1 236 ? -51.386 -19.443 -57.207 1.00 38.00 ? 298 ASN A ND2 1 +ATOM 1642 N N . GLU A 1 237 ? -47.760 -22.112 -57.694 1.00 55.04 ? 299 GLU A N 1 +ATOM 1643 C CA . GLU A 1 237 ? -46.616 -22.398 -58.552 1.00 54.89 ? 299 GLU A CA 1 +ATOM 1644 C C . GLU A 1 237 ? -46.200 -21.177 -59.366 1.00 54.97 ? 299 GLU A C 1 +ATOM 1645 O O . GLU A 1 237 ? -45.023 -21.042 -59.724 1.00 48.63 ? 299 GLU A O 1 +ATOM 1646 C CB . GLU A 1 237 ? -46.952 -23.587 -59.449 1.00 49.51 ? 299 GLU A CB 1 +ATOM 1647 C CG . GLU A 1 237 ? -47.686 -24.690 -58.689 1.00 53.76 ? 299 GLU A CG 1 +ATOM 1648 C CD . GLU A 1 237 ? -46.807 -25.888 -58.351 1.00 55.74 ? 299 GLU A CD 1 +ATOM 1649 O OE1 . GLU A 1 237 ? -45.618 -25.701 -57.997 1.00 46.31 ? 299 GLU A OE1 1 +ATOM 1650 O OE2 . GLU A 1 237 ? -47.318 -27.025 -58.436 1.00 55.36 ? 299 GLU A OE2 1 +ATOM 1651 N N . ILE A 1 238 ? -47.136 -20.269 -59.644 1.00 55.09 ? 300 ILE A N 1 +ATOM 1652 C CA . ILE A 1 238 ? -46.789 -19.044 -60.354 1.00 47.54 ? 300 ILE A CA 1 +ATOM 1653 C C . ILE A 1 238 ? -45.986 -18.125 -59.451 1.00 49.97 ? 300 ILE A C 1 +ATOM 1654 O O . ILE A 1 238 ? -44.951 -17.578 -59.850 1.00 47.51 ? 300 ILE A O 1 +ATOM 1655 C CB . ILE A 1 238 ? -48.059 -18.336 -60.848 1.00 38.00 ? 300 ILE A CB 1 +ATOM 1656 C CG1 . ILE A 1 238 ? -49.062 -19.346 -61.378 1.00 38.00 ? 300 ILE A CG1 1 +ATOM 1657 C CG2 . ILE A 1 238 ? -47.713 -17.329 -61.912 1.00 41.22 ? 300 ILE A CG2 1 +ATOM 1658 C CD1 . ILE A 1 238 ? -50.353 -18.719 -61.789 1.00 38.00 ? 300 ILE A CD1 1 +ATOM 1659 N N . LEU A 1 239 ? -46.447 -17.957 -58.210 1.00 47.39 ? 301 LEU A N 1 +ATOM 1660 C CA . LEU A 1 239 ? -45.802 -17.021 -57.302 1.00 48.85 ? 301 LEU A CA 1 +ATOM 1661 C C . LEU A 1 239 ? -44.354 -17.411 -57.042 1.00 52.69 ? 301 LEU A C 1 +ATOM 1662 O O . LEU A 1 239 ? -43.492 -16.538 -56.890 1.00 50.00 ? 301 LEU A O 1 +ATOM 1663 C CB . LEU A 1 239 ? -46.595 -16.947 -55.997 1.00 51.61 ? 301 LEU A CB 1 +ATOM 1664 C CG . LEU A 1 239 ? -46.334 -15.760 -55.070 1.00 50.33 ? 301 LEU A CG 1 +ATOM 1665 C CD1 . LEU A 1 239 ? -46.459 -14.455 -55.828 1.00 41.92 ? 301 LEU A CD1 1 +ATOM 1666 C CD2 . LEU A 1 239 ? -47.299 -15.788 -53.899 1.00 50.20 ? 301 LEU A CD2 1 +ATOM 1667 N N . GLN A 1 240 ? -44.055 -18.710 -57.025 1.00 54.69 ? 302 GLN A N 1 +ATOM 1668 C CA . GLN A 1 240 ? -42.666 -19.123 -56.903 1.00 55.43 ? 302 GLN A CA 1 +ATOM 1669 C C . GLN A 1 240 ? -41.859 -18.749 -58.136 1.00 51.68 ? 302 GLN A C 1 +ATOM 1670 O O . GLN A 1 240 ? -40.643 -18.559 -58.035 1.00 50.29 ? 302 GLN A O 1 +ATOM 1671 C CB . GLN A 1 240 ? -42.575 -20.631 -56.663 1.00 57.16 ? 302 GLN A CB 1 +ATOM 1672 C CG . GLN A 1 240 ? -43.244 -21.105 -55.387 1.00 60.56 ? 302 GLN A CG 1 +ATOM 1673 C CD . GLN A 1 240 ? -43.352 -22.613 -55.318 1.00 65.05 ? 302 GLN A CD 1 +ATOM 1674 O OE1 . GLN A 1 240 ? -44.049 -23.237 -56.120 1.00 63.37 ? 302 GLN A OE1 1 +ATOM 1675 N NE2 . GLN A 1 240 ? -42.650 -23.211 -54.362 1.00 73.75 ? 302 GLN A NE2 1 +ATOM 1676 N N . SER A 1 241 ? -42.516 -18.583 -59.281 1.00 49.57 ? 303 SER A N 1 +ATOM 1677 C CA . SER A 1 241 ? -41.807 -18.331 -60.526 1.00 54.59 ? 303 SER A CA 1 +ATOM 1678 C C . SER A 1 241 ? -41.353 -16.887 -60.667 1.00 54.83 ? 303 SER A C 1 +ATOM 1679 O O . SER A 1 241 ? -40.447 -16.612 -61.464 1.00 54.30 ? 303 SER A O 1 +ATOM 1680 C CB . SER A 1 241 ? -42.703 -18.687 -61.709 1.00 58.88 ? 303 SER A CB 1 +ATOM 1681 O OG . SER A 1 241 ? -43.645 -17.650 -61.933 1.00 50.68 ? 303 SER A OG 1 +ATOM 1682 N N . VAL A 1 242 ? -41.945 -15.965 -59.903 1.00 51.97 ? 304 VAL A N 1 +ATOM 1683 C CA . VAL A 1 242 ? -41.632 -14.548 -60.028 1.00 46.51 ? 304 VAL A CA 1 +ATOM 1684 C C . VAL A 1 242 ? -40.572 -14.095 -59.038 1.00 41.27 ? 304 VAL A C 1 +ATOM 1685 O O . VAL A 1 242 ? -40.252 -12.903 -58.988 1.00 42.98 ? 304 VAL A O 1 +ATOM 1686 C CB . VAL A 1 242 ? -42.906 -13.693 -59.873 1.00 42.03 ? 304 VAL A CB 1 +ATOM 1687 C CG1 . VAL A 1 242 ? -43.964 -14.133 -60.874 1.00 43.57 ? 304 VAL A CG1 1 +ATOM 1688 C CG2 . VAL A 1 242 ? -43.429 -13.771 -58.458 1.00 41.29 ? 304 VAL A CG2 1 +ATOM 1689 N N . PHE A 1 243 ? -40.006 -15.008 -58.262 1.00 44.26 ? 305 PHE A N 1 +ATOM 1690 C CA . PHE A 1 243 ? -38.941 -14.680 -57.326 1.00 47.77 ? 305 PHE A CA 1 +ATOM 1691 C C . PHE A 1 243 ? -37.600 -14.996 -57.971 1.00 47.02 ? 305 PHE A C 1 +ATOM 1692 O O . PHE A 1 243 ? -37.379 -16.119 -58.434 1.00 57.85 ? 305 PHE A O 1 +ATOM 1693 C CB . PHE A 1 243 ? -39.108 -15.448 -56.013 1.00 52.19 ? 305 PHE A CB 1 +ATOM 1694 C CG . PHE A 1 243 ? -40.072 -14.804 -55.047 1.00 43.34 ? 305 PHE A CG 1 +ATOM 1695 C CD1 . PHE A 1 243 ? -41.427 -15.085 -55.102 1.00 39.74 ? 305 PHE A CD1 1 +ATOM 1696 C CD2 . PHE A 1 243 ? -39.617 -13.918 -54.083 1.00 38.41 ? 305 PHE A CD2 1 +ATOM 1697 C CE1 . PHE A 1 243 ? -42.308 -14.492 -54.221 1.00 38.00 ? 305 PHE A CE1 1 +ATOM 1698 C CE2 . PHE A 1 243 ? -40.493 -13.324 -53.198 1.00 38.00 ? 305 PHE A CE2 1 +ATOM 1699 C CZ . PHE A 1 243 ? -41.840 -13.613 -53.267 1.00 38.00 ? 305 PHE A CZ 1 +ATOM 1700 N N . PHE A 1 244 ? -36.718 -14.003 -58.020 1.00 40.51 ? 306 PHE A N 1 +ATOM 1701 C CA . PHE A 1 244 ? -35.388 -14.185 -58.577 1.00 45.82 ? 306 PHE A CA 1 +ATOM 1702 C C . PHE A 1 244 ? -34.398 -13.454 -57.685 1.00 41.80 ? 306 PHE A C 1 +ATOM 1703 O O . PHE A 1 244 ? -34.749 -12.944 -56.618 1.00 42.14 ? 306 PHE A O 1 +ATOM 1704 C CB . PHE A 1 244 ? -35.324 -13.709 -60.035 1.00 60.91 ? 306 PHE A CB 1 +ATOM 1705 C CG . PHE A 1 244 ? -35.602 -12.239 -60.216 1.00 62.23 ? 306 PHE A CG 1 +ATOM 1706 C CD1 . PHE A 1 244 ? -36.898 -11.786 -60.422 1.00 55.65 ? 306 PHE A CD1 1 +ATOM 1707 C CD2 . PHE A 1 244 ? -34.569 -11.311 -60.178 1.00 53.49 ? 306 PHE A CD2 1 +ATOM 1708 C CE1 . PHE A 1 244 ? -37.158 -10.441 -60.591 1.00 52.16 ? 306 PHE A CE1 1 +ATOM 1709 C CE2 . PHE A 1 244 ? -34.826 -9.963 -60.344 1.00 54.27 ? 306 PHE A CE2 1 +ATOM 1710 C CZ . PHE A 1 244 ? -36.122 -9.530 -60.553 1.00 56.25 ? 306 PHE A CZ 1 +ATOM 1711 N N . VAL A 1 245 ? -33.142 -13.421 -58.114 1.00 41.83 ? 307 VAL A N 1 +ATOM 1712 C CA . VAL A 1 245 ? -32.076 -12.769 -57.367 1.00 46.99 ? 307 VAL A CA 1 +ATOM 1713 C C . VAL A 1 245 ? -31.426 -11.740 -58.282 1.00 50.09 ? 307 VAL A C 1 +ATOM 1714 O O . VAL A 1 245 ? -31.166 -12.023 -59.457 1.00 46.81 ? 307 VAL A O 1 +ATOM 1715 C CB . VAL A 1 245 ? -31.049 -13.785 -56.832 1.00 39.50 ? 307 VAL A CB 1 +ATOM 1716 C CG1 . VAL A 1 245 ? -29.945 -13.077 -56.072 1.00 39.36 ? 307 VAL A CG1 1 +ATOM 1717 C CG2 . VAL A 1 245 ? -31.729 -14.793 -55.931 1.00 38.00 ? 307 VAL A CG2 1 +ATOM 1718 N N . SER A 1 246 ? -31.198 -10.543 -57.750 1.00 53.83 ? 308 SER A N 1 +ATOM 1719 C CA . SER A 1 246 ? -30.647 -9.433 -58.503 1.00 46.48 ? 308 SER A CA 1 +ATOM 1720 C C . SER A 1 246 ? -29.143 -9.587 -58.660 1.00 46.21 ? 308 SER A C 1 +ATOM 1721 O O . SER A 1 246 ? -28.510 -10.353 -57.933 1.00 52.83 ? 308 SER A O 1 +ATOM 1722 C CB . SER A 1 246 ? -30.946 -8.121 -57.783 1.00 48.53 ? 308 SER A CB 1 +ATOM 1723 O OG . SER A 1 246 ? -32.325 -7.818 -57.831 1.00 59.68 ? 308 SER A OG 1 +ATOM 1724 N N . PRO A 1 247 ? -28.539 -8.856 -59.599 1.00 49.54 ? 309 PRO A N 1 +ATOM 1725 C CA . PRO A 1 247 ? -27.069 -8.768 -59.618 1.00 52.07 ? 309 PRO A CA 1 +ATOM 1726 C C . PRO A 1 247 ? -26.484 -8.232 -58.323 1.00 60.29 ? 309 PRO A C 1 +ATOM 1727 O O . PRO A 1 247 ? -25.286 -8.426 -58.074 1.00 58.83 ? 309 PRO A O 1 +ATOM 1728 C CB . PRO A 1 247 ? -26.787 -7.832 -60.798 1.00 53.22 ? 309 PRO A CB 1 +ATOM 1729 C CG . PRO A 1 247 ? -27.971 -8.008 -61.696 1.00 54.94 ? 309 PRO A CG 1 +ATOM 1730 C CD . PRO A 1 247 ? -29.147 -8.233 -60.787 1.00 49.54 ? 309 PRO A CD 1 +ATOM 1731 N N . ALA A 1 248 ? -27.284 -7.545 -57.503 1.00 58.07 ? 310 ALA A N 1 +ATOM 1732 C CA . ALA A 1 248 ? -26.884 -7.100 -56.175 1.00 53.00 ? 310 ALA A CA 1 +ATOM 1733 C C . ALA A 1 248 ? -27.140 -8.149 -55.107 1.00 54.19 ? 310 ALA A C 1 +ATOM 1734 O O . ALA A 1 248 ? -26.916 -7.874 -53.924 1.00 62.98 ? 310 ALA A O 1 +ATOM 1735 C CB . ALA A 1 248 ? -27.622 -5.810 -55.807 1.00 53.16 ? 310 ALA A CB 1 +ATOM 1736 N N . SER A 1 249 ? -27.589 -9.341 -55.503 1.00 50.45 ? 311 SER A N 1 +ATOM 1737 C CA . SER A 1 249 ? -27.831 -10.460 -54.592 1.00 45.52 ? 311 SER A CA 1 +ATOM 1738 C C . SER A 1 249 ? -28.961 -10.145 -53.609 1.00 41.75 ? 311 SER A C 1 +ATOM 1739 O O . SER A 1 249 ? -28.836 -10.331 -52.399 1.00 44.41 ? 311 SER A O 1 +ATOM 1740 C CB . SER A 1 249 ? -26.547 -10.834 -53.848 1.00 45.08 ? 311 SER A CB 1 +ATOM 1741 O OG . SER A 1 249 ? -25.458 -10.947 -54.747 1.00 41.11 ? 311 SER A OG 1 +ATOM 1742 N N . ASN A 1 250 ? -30.090 -9.698 -54.148 1.00 40.80 ? 312 ASN A N 1 +ATOM 1743 C CA . ASN A 1 250 ? -31.279 -9.393 -53.365 1.00 45.26 ? 312 ASN A CA 1 +ATOM 1744 C C . ASN A 1 250 ? -32.435 -10.262 -53.837 1.00 40.64 ? 312 ASN A C 1 +ATOM 1745 O O . ASN A 1 250 ? -32.575 -10.527 -55.033 1.00 41.08 ? 312 ASN A O 1 +ATOM 1746 C CB . ASN A 1 250 ? -31.680 -7.907 -53.475 1.00 54.11 ? 312 ASN A CB 1 +ATOM 1747 C CG . ASN A 1 250 ? -30.655 -6.959 -52.860 1.00 56.02 ? 312 ASN A CG 1 +ATOM 1748 O OD1 . ASN A 1 250 ? -29.907 -7.329 -51.956 1.00 52.81 ? 312 ASN A OD1 1 +ATOM 1749 N ND2 . ASN A 1 250 ? -30.611 -5.727 -53.369 1.00 57.73 ? 312 ASN A ND2 1 +ATOM 1750 N N . VAL A 1 251 ? -33.242 -10.729 -52.892 1.00 39.29 ? 313 VAL A N 1 +ATOM 1751 C CA . VAL A 1 251 ? -34.447 -11.482 -53.218 1.00 38.43 ? 313 VAL A CA 1 +ATOM 1752 C C . VAL A 1 251 ? -35.504 -10.494 -53.689 1.00 47.11 ? 313 VAL A C 1 +ATOM 1753 O O . VAL A 1 251 ? -35.924 -9.617 -52.927 1.00 55.24 ? 313 VAL A O 1 +ATOM 1754 C CB . VAL A 1 251 ? -34.946 -12.285 -52.010 1.00 38.00 ? 313 VAL A CB 1 +ATOM 1755 C CG1 . VAL A 1 251 ? -36.268 -12.957 -52.327 1.00 38.00 ? 313 VAL A CG1 1 +ATOM 1756 C CG2 . VAL A 1 251 ? -33.910 -13.307 -51.592 1.00 38.00 ? 313 VAL A CG2 1 +ATOM 1757 N N . CYS A 1 252 ? -35.912 -10.609 -54.950 1.00 46.84 ? 314 CYS A N 1 +ATOM 1758 C CA . CYS A 1 252 ? -36.898 -9.717 -55.539 1.00 41.40 ? 314 CYS A CA 1 +ATOM 1759 C C . CYS A 1 252 ? -38.077 -10.511 -56.086 1.00 42.24 ? 314 CYS A C 1 +ATOM 1760 O O . CYS A 1 252 ? -37.958 -11.691 -56.424 1.00 44.35 ? 314 CYS A O 1 +ATOM 1761 C CB . CYS A 1 252 ? -36.283 -8.890 -56.662 1.00 45.27 ? 314 CYS A CB 1 +ATOM 1762 S SG . CYS A 1 252 ? -34.677 -8.196 -56.275 1.00 85.00 ? 314 CYS A SG 1 +ATOM 1763 N N . PHE A 1 253 ? -39.215 -9.836 -56.203 1.00 43.12 ? 315 PHE A N 1 +ATOM 1764 C CA . PHE A 1 253 ? -40.380 -10.403 -56.865 1.00 44.16 ? 315 PHE A CA 1 +ATOM 1765 C C . PHE A 1 253 ? -41.153 -9.266 -57.518 1.00 52.08 ? 315 PHE A C 1 +ATOM 1766 O O . PHE A 1 253 ? -40.845 -8.089 -57.322 1.00 58.03 ? 315 PHE A O 1 +ATOM 1767 C CB . PHE A 1 253 ? -41.261 -11.208 -55.900 1.00 44.99 ? 315 PHE A CB 1 +ATOM 1768 C CG . PHE A 1 253 ? -42.001 -10.371 -54.889 1.00 48.39 ? 315 PHE A CG 1 +ATOM 1769 C CD1 . PHE A 1 253 ? -41.335 -9.457 -54.087 1.00 43.69 ? 315 PHE A CD1 1 +ATOM 1770 C CD2 . PHE A 1 253 ? -43.375 -10.494 -54.755 1.00 45.59 ? 315 PHE A CD2 1 +ATOM 1771 C CE1 . PHE A 1 253 ? -42.025 -8.692 -53.168 1.00 44.20 ? 315 PHE A CE1 1 +ATOM 1772 C CE2 . PHE A 1 253 ? -44.069 -9.732 -53.839 1.00 42.43 ? 315 PHE A CE2 1 +ATOM 1773 C CZ . PHE A 1 253 ? -43.393 -8.829 -53.046 1.00 46.19 ? 315 PHE A CZ 1 +ATOM 1774 N N . PHE A 1 254 ? -42.151 -9.625 -58.323 1.00 45.01 ? 316 PHE A N 1 +ATOM 1775 C CA . PHE A 1 254 ? -42.811 -8.646 -59.177 1.00 38.76 ? 316 PHE A CA 1 +ATOM 1776 C C . PHE A 1 254 ? -44.216 -9.121 -59.508 1.00 38.00 ? 316 PHE A C 1 +ATOM 1777 O O . PHE A 1 254 ? -44.573 -10.277 -59.271 1.00 41.84 ? 316 PHE A O 1 +ATOM 1778 C CB . PHE A 1 254 ? -42.015 -8.408 -60.466 1.00 41.11 ? 316 PHE A CB 1 +ATOM 1779 C CG . PHE A 1 254 ? -41.769 -9.662 -61.270 1.00 44.73 ? 316 PHE A CG 1 +ATOM 1780 C CD1 . PHE A 1 254 ? -42.713 -10.123 -62.180 1.00 44.29 ? 316 PHE A CD1 1 +ATOM 1781 C CD2 . PHE A 1 254 ? -40.592 -10.378 -61.116 1.00 46.32 ? 316 PHE A CD2 1 +ATOM 1782 C CE1 . PHE A 1 254 ? -42.490 -11.274 -62.916 1.00 39.37 ? 316 PHE A CE1 1 +ATOM 1783 C CE2 . PHE A 1 254 ? -40.364 -11.530 -61.850 1.00 44.85 ? 316 PHE A CE2 1 +ATOM 1784 C CZ . PHE A 1 254 ? -41.314 -11.976 -62.752 1.00 43.49 ? 316 PHE A CZ 1 +ATOM 1785 N N . ALA A 1 255 ? -45.017 -8.200 -60.034 1.00 38.00 ? 317 ALA A N 1 +ATOM 1786 C CA . ALA A 1 255 ? -46.300 -8.563 -60.620 1.00 42.14 ? 317 ALA A CA 1 +ATOM 1787 C C . ALA A 1 255 ? -46.083 -9.060 -62.044 1.00 49.25 ? 317 ALA A C 1 +ATOM 1788 O O . ALA A 1 255 ? -45.340 -8.444 -62.816 1.00 49.70 ? 317 ALA A O 1 +ATOM 1789 C CB . ALA A 1 255 ? -47.257 -7.374 -60.609 1.00 44.58 ? 317 ALA A CB 1 +ATOM 1790 N N . LYS A 1 256 ? -46.723 -10.182 -62.386 1.00 59.45 ? 318 LYS A N 1 +ATOM 1791 C CA . LYS A 1 256 ? -46.444 -10.846 -63.660 1.00 56.19 ? 318 LYS A CA 1 +ATOM 1792 C C . LYS A 1 256 ? -46.761 -9.944 -64.846 1.00 57.57 ? 318 LYS A C 1 +ATOM 1793 O O . LYS A 1 256 ? -45.922 -9.753 -65.734 1.00 60.17 ? 318 LYS A O 1 +ATOM 1794 C CB . LYS A 1 256 ? -47.246 -12.147 -63.758 1.00 66.79 ? 318 LYS A CB 1 +ATOM 1795 C CG . LYS A 1 256 ? -46.912 -13.027 -64.971 1.00 74.26 ? 318 LYS A CG 1 +ATOM 1796 C CD . LYS A 1 256 ? -45.694 -13.909 -64.725 1.00 77.88 ? 318 LYS A CD 1 +ATOM 1797 C CE . LYS A 1 256 ? -45.413 -14.835 -65.904 1.00 64.97 ? 318 LYS A CE 1 +ATOM 1798 N NZ . LYS A 1 256 ? -44.226 -15.700 -65.647 1.00 75.26 ? 318 LYS A NZ 1 +ATOM 1799 N N . CYS A 1 257 ? -47.960 -9.350 -64.866 1.00 55.31 ? 319 CYS A N 1 +ATOM 1800 C CA . CYS A 1 257 ? -48.354 -8.573 -66.042 1.00 56.17 ? 319 CYS A CA 1 +ATOM 1801 C C . CYS A 1 257 ? -47.585 -7.261 -66.147 1.00 49.38 ? 319 CYS A C 1 +ATOM 1802 O O . CYS A 1 257 ? -47.000 -7.000 -67.212 1.00 50.66 ? 319 CYS A O 1 +ATOM 1803 C CB . CYS A 1 257 ? -49.874 -8.370 -66.048 1.00 57.55 ? 319 CYS A CB 1 +ATOM 1804 S SG . CYS A 1 257 ? -50.536 -7.405 -67.435 1.00 69.37 ? 319 CYS A SG 1 +ATOM 1805 N N . PRO A 1 258 ? -47.517 -6.412 -65.117 1.00 47.56 ? 320 PRO A N 1 +ATOM 1806 C CA . PRO A 1 258 ? -46.753 -5.167 -65.272 1.00 48.54 ? 320 PRO A CA 1 +ATOM 1807 C C . PRO A 1 258 ? -45.290 -5.381 -65.598 1.00 49.11 ? 320 PRO A C 1 +ATOM 1808 O O . PRO A 1 258 ? -44.707 -4.538 -66.288 1.00 62.39 ? 320 PRO A O 1 +ATOM 1809 C CB . PRO A 1 258 ? -46.931 -4.472 -63.918 1.00 51.84 ? 320 PRO A CB 1 +ATOM 1810 C CG . PRO A 1 258 ? -48.206 -4.977 -63.435 1.00 60.17 ? 320 PRO A CG 1 +ATOM 1811 C CD . PRO A 1 258 ? -48.272 -6.412 -63.855 1.00 55.08 ? 320 PRO A CD 1 +ATOM 1812 N N . TYR A 1 259 ? -44.657 -6.449 -65.110 1.00 42.42 ? 321 TYR A N 1 +ATOM 1813 C CA . TYR A 1 259 ? -43.267 -6.669 -65.497 1.00 45.30 ? 321 TYR A CA 1 +ATOM 1814 C C . TYR A 1 259 ? -43.157 -6.976 -66.984 1.00 48.35 ? 321 TYR A C 1 +ATOM 1815 O O . TYR A 1 259 ? -42.237 -6.498 -67.655 1.00 50.51 ? 321 TYR A O 1 +ATOM 1816 C CB . TYR A 1 259 ? -42.636 -7.791 -64.680 1.00 43.71 ? 321 TYR A CB 1 +ATOM 1817 C CG . TYR A 1 259 ? -41.116 -7.803 -64.719 1.00 39.46 ? 321 TYR A CG 1 +ATOM 1818 C CD1 . TYR A 1 259 ? -40.394 -6.723 -65.215 1.00 46.71 ? 321 TYR A CD1 1 +ATOM 1819 C CD2 . TYR A 1 259 ? -40.407 -8.909 -64.286 1.00 49.92 ? 321 TYR A CD2 1 +ATOM 1820 C CE1 . TYR A 1 259 ? -39.001 -6.744 -65.252 1.00 60.40 ? 321 TYR A CE1 1 +ATOM 1821 C CE2 . TYR A 1 259 ? -39.023 -8.941 -64.321 1.00 61.46 ? 321 TYR A CE2 1 +ATOM 1822 C CZ . TYR A 1 259 ? -38.321 -7.859 -64.802 1.00 63.81 ? 321 TYR A CZ 1 +ATOM 1823 O OH . TYR A 1 259 ? -36.940 -7.908 -64.827 1.00 56.34 ? 321 TYR A OH 1 +ATOM 1824 N N . MET A 1 260 ? -44.081 -7.773 -67.520 1.00 47.42 ? 322 MET A N 1 +ATOM 1825 C CA . MET A 1 260 ? -44.028 -8.108 -68.940 1.00 59.87 ? 322 MET A CA 1 +ATOM 1826 C C . MET A 1 260 ? -44.160 -6.862 -69.806 1.00 55.27 ? 322 MET A C 1 +ATOM 1827 O O . MET A 1 260 ? -43.384 -6.659 -70.746 1.00 64.58 ? 322 MET A O 1 +ATOM 1828 C CB . MET A 1 260 ? -45.120 -9.122 -69.279 1.00 66.32 ? 322 MET A CB 1 +ATOM 1829 C CG . MET A 1 260 ? -45.393 -9.282 -70.770 1.00 62.34 ? 322 MET A CG 1 +ATOM 1830 S SD . MET A 1 260 ? -46.272 -10.810 -71.141 1.00 91.89 ? 322 MET A SD 1 +ATOM 1831 C CE . MET A 1 260 ? -47.349 -10.964 -69.714 1.00 65.23 ? 322 MET A CE 1 +ATOM 1832 N N . CYS A 1 261 ? -45.113 -5.995 -69.483 1.00 46.22 ? 323 CYS A N 1 +ATOM 1833 C CA . CYS A 1 261 ? -45.273 -4.771 -70.251 1.00 50.03 ? 323 CYS A CA 1 +ATOM 1834 C C . CYS A 1 261 ? -44.229 -3.716 -69.908 1.00 56.18 ? 323 CYS A C 1 +ATOM 1835 O O . CYS A 1 261 ? -44.238 -2.646 -70.522 1.00 66.42 ? 323 CYS A O 1 +ATOM 1836 C CB . CYS A 1 261 ? -46.681 -4.207 -70.048 1.00 53.69 ? 323 CYS A CB 1 +ATOM 1837 S SG . CYS A 1 261 ? -48.026 -5.216 -70.714 1.00 61.08 ? 323 CYS A SG 1 +ATOM 1838 N N . LYS A 1 262 ? -43.327 -3.998 -68.964 1.00 53.83 ? 324 LYS A N 1 +ATOM 1839 C CA . LYS A 1 262 ? -42.271 -3.064 -68.558 1.00 55.48 ? 324 LYS A CA 1 +ATOM 1840 C C . LYS A 1 262 ? -42.853 -1.720 -68.117 1.00 53.44 ? 324 LYS A C 1 +ATOM 1841 O O . LYS A 1 262 ? -42.249 -0.661 -68.309 1.00 51.91 ? 324 LYS A O 1 +ATOM 1842 C CB . LYS A 1 262 ? -41.245 -2.882 -69.679 1.00 55.49 ? 324 LYS A CB 1 +ATOM 1843 C CG . LYS A 1 262 ? -40.688 -4.205 -70.187 1.00 55.28 ? 324 LYS A CG 1 +ATOM 1844 C CD . LYS A 1 262 ? -39.865 -4.908 -69.114 1.00 63.93 ? 324 LYS A CD 1 +ATOM 1845 C CE . LYS A 1 262 ? -39.643 -6.382 -69.441 1.00 58.88 ? 324 LYS A CE 1 +ATOM 1846 N NZ . LYS A 1 262 ? -38.501 -6.965 -68.673 1.00 55.75 ? 324 LYS A NZ 1 +ATOM 1847 N N . THR A 1 263 ? -44.031 -1.771 -67.496 1.00 49.78 ? 325 THR A N 1 +ATOM 1848 C CA . THR A 1 263 ? -44.650 -0.584 -66.928 1.00 53.79 ? 325 THR A CA 1 +ATOM 1849 C C . THR A 1 263 ? -44.183 -0.316 -65.503 1.00 54.90 ? 325 THR A C 1 +ATOM 1850 O O . THR A 1 263 ? -44.140 0.843 -65.077 1.00 50.94 ? 325 THR A O 1 +ATOM 1851 C CB . THR A 1 263 ? -46.182 -0.714 -66.966 1.00 51.38 ? 325 THR A CB 1 +ATOM 1852 O OG1 . THR A 1 263 ? -46.737 -0.309 -65.708 1.00 66.76 ? 325 THR A OG1 1 +ATOM 1853 C CG2 . THR A 1 263 ? -46.604 -2.131 -67.261 1.00 42.06 ? 325 THR A CG2 1 +ATOM 1854 N N . GLU A 1 264 ? -43.792 -1.351 -64.766 1.00 52.76 ? 326 GLU A N 1 +ATOM 1855 C CA . GLU A 1 264 ? -43.234 -1.167 -63.436 1.00 52.94 ? 326 GLU A CA 1 +ATOM 1856 C C . GLU A 1 264 ? -42.002 -2.047 -63.291 1.00 52.31 ? 326 GLU A C 1 +ATOM 1857 O O . GLU A 1 264 ? -41.663 -2.831 -64.182 1.00 50.65 ? 326 GLU A O 1 +ATOM 1858 C CB . GLU A 1 264 ? -44.258 -1.487 -62.345 1.00 49.95 ? 326 GLU A CB 1 +ATOM 1859 C CG . GLU A 1 264 ? -44.333 -2.950 -62.008 1.00 48.37 ? 326 GLU A CG 1 +ATOM 1860 C CD . GLU A 1 264 ? -45.240 -3.229 -60.836 1.00 55.29 ? 326 GLU A CD 1 +ATOM 1861 O OE1 . GLU A 1 264 ? -46.270 -2.534 -60.698 1.00 56.89 ? 326 GLU A OE1 1 +ATOM 1862 O OE2 . GLU A 1 264 ? -44.907 -4.132 -60.037 1.00 50.55 ? 326 GLU A OE2 1 +ATOM 1863 N N . TYR A 1 265 ? -41.307 -1.888 -62.167 1.00 53.79 ? 327 TYR A N 1 +ATOM 1864 C CA . TYR A 1 265 ? -40.104 -2.658 -61.895 1.00 54.10 ? 327 TYR A CA 1 +ATOM 1865 C C . TYR A 1 265 ? -40.425 -3.751 -60.882 1.00 51.22 ? 327 TYR A C 1 +ATOM 1866 O O . TYR A 1 265 ? -41.589 -4.011 -60.556 1.00 47.94 ? 327 TYR A O 1 +ATOM 1867 C CB . TYR A 1 265 ? -38.998 -1.738 -61.379 1.00 60.01 ? 327 TYR A CB 1 +ATOM 1868 C CG . TYR A 1 265 ? -38.670 -0.587 -62.299 1.00 62.48 ? 327 TYR A CG 1 +ATOM 1869 C CD1 . TYR A 1 265 ? -38.736 -0.727 -63.677 1.00 72.21 ? 327 TYR A CD1 1 +ATOM 1870 C CD2 . TYR A 1 265 ? -38.323 0.655 -61.783 1.00 60.93 ? 327 TYR A CD2 1 +ATOM 1871 C CE1 . TYR A 1 265 ? -38.441 0.331 -64.518 1.00 68.41 ? 327 TYR A CE1 1 +ATOM 1872 C CE2 . TYR A 1 265 ? -38.031 1.717 -62.616 1.00 64.62 ? 327 TYR A CE2 1 +ATOM 1873 C CZ . TYR A 1 265 ? -38.091 1.550 -63.980 1.00 62.04 ? 327 TYR A CZ 1 +ATOM 1874 O OH . TYR A 1 265 ? -37.803 2.610 -64.807 1.00 60.97 ? 327 TYR A OH 1 +ATOM 1875 N N . ALA A 1 266 ? -39.383 -4.360 -60.330 1.00 40.12 ? 328 ALA A N 1 +ATOM 1876 C CA . ALA A 1 266 ? -39.563 -5.340 -59.278 1.00 38.00 ? 328 ALA A CA 1 +ATOM 1877 C C . ALA A 1 266 ? -39.431 -4.669 -57.920 1.00 45.82 ? 328 ALA A C 1 +ATOM 1878 O O . ALA A 1 266 ? -39.087 -3.492 -57.807 1.00 55.65 ? 328 ALA A O 1 +ATOM 1879 C CB . ALA A 1 266 ? -38.555 -6.480 -59.420 1.00 42.71 ? 328 ALA A CB 1 +ATOM 1880 N N . VAL A 1 267 ? -39.704 -5.450 -56.882 1.00 44.79 ? 329 VAL A N 1 +ATOM 1881 C CA . VAL A 1 267 ? -39.654 -5.004 -55.496 1.00 38.00 ? 329 VAL A CA 1 +ATOM 1882 C C . VAL A 1 267 ? -38.653 -5.902 -54.798 1.00 38.00 ? 329 VAL A C 1 +ATOM 1883 O O . VAL A 1 267 ? -38.894 -7.105 -54.652 1.00 49.49 ? 329 VAL A O 1 +ATOM 1884 C CB . VAL A 1 267 ? -41.024 -5.074 -54.810 1.00 38.00 ? 329 VAL A CB 1 +ATOM 1885 C CG1 . VAL A 1 267 ? -40.909 -4.606 -53.392 1.00 48.76 ? 329 VAL A CG1 1 +ATOM 1886 C CG2 . VAL A 1 267 ? -42.049 -4.235 -55.555 1.00 38.00 ? 329 VAL A CG2 1 +ATOM 1887 N N . CYS A 1 268 ? -37.500 -5.350 -54.444 1.00 38.00 ? 330 CYS A N 1 +ATOM 1888 C CA . CYS A 1 268 ? -36.430 -6.122 -53.826 1.00 53.18 ? 330 CYS A CA 1 +ATOM 1889 C C . CYS A 1 268 ? -36.329 -5.877 -52.324 1.00 51.62 ? 330 CYS A C 1 +ATOM 1890 O O . CYS A 1 268 ? -36.603 -4.781 -51.830 1.00 55.39 ? 330 CYS A O 1 +ATOM 1891 C CB . CYS A 1 268 ? -35.085 -5.808 -54.472 1.00 61.32 ? 330 CYS A CB 1 +ATOM 1892 S SG . CYS A 1 268 ? -34.999 -6.192 -56.222 1.00 72.27 ? 330 CYS A SG 1 +ATOM 1893 N N . GLY A 1 269 ? -35.930 -6.923 -51.601 1.00 41.92 ? 331 GLY A N 1 +ATOM 1894 C CA . GLY A 1 269 ? -35.467 -6.764 -50.242 1.00 46.95 ? 331 GLY A CA 1 +ATOM 1895 C C . GLY A 1 269 ? -34.019 -6.309 -50.190 1.00 52.63 ? 331 GLY A C 1 +ATOM 1896 O O . GLY A 1 269 ? -33.330 -6.193 -51.203 1.00 49.78 ? 331 GLY A O 1 +ATOM 1897 N N . LYS A 1 270 ? -33.539 -6.102 -48.964 1.00 58.78 ? 332 LYS A N 1 +ATOM 1898 C CA . LYS A 1 270 ? -32.173 -5.645 -48.702 1.00 61.08 ? 332 LYS A CA 1 +ATOM 1899 C C . LYS A 1 270 ? -31.519 -6.544 -47.656 1.00 59.89 ? 332 LYS A C 1 +ATOM 1900 O O . LYS A 1 270 ? -31.390 -6.168 -46.484 1.00 62.39 ? 332 LYS A O 1 +ATOM 1901 C CB . LYS A 1 270 ? -32.158 -4.185 -48.242 1.00 67.82 ? 332 LYS A CB 1 +ATOM 1902 C CG . LYS A 1 270 ? -31.603 -3.185 -49.259 1.00 68.97 ? 332 LYS A CG 1 +ATOM 1903 C CD . LYS A 1 270 ? -32.561 -2.965 -50.426 1.00 80.84 ? 332 LYS A CD 1 +ATOM 1904 C CE . LYS A 1 270 ? -32.089 -1.837 -51.341 1.00 82.38 ? 332 LYS A CE 1 +ATOM 1905 N NZ . LYS A 1 270 ? -30.793 -2.160 -52.000 1.00 78.07 ? 332 LYS A NZ 1 +ATOM 1906 N N . PRO A 1 271 ? -31.147 -7.776 -48.036 1.00 53.46 ? 333 PRO A N 1 +ATOM 1907 C CA . PRO A 1 271 ? -31.445 -8.412 -49.320 1.00 46.40 ? 333 PRO A CA 1 +ATOM 1908 C C . PRO A 1 271 ? -32.753 -9.190 -49.226 1.00 46.15 ? 333 PRO A C 1 +ATOM 1909 O O . PRO A 1 271 ? -33.377 -9.454 -50.251 1.00 47.14 ? 333 PRO A O 1 +ATOM 1910 C CB . PRO A 1 271 ? -30.240 -9.328 -49.555 1.00 41.17 ? 333 PRO A CB 1 +ATOM 1911 C CG . PRO A 1 271 ? -29.635 -9.553 -48.205 1.00 45.91 ? 333 PRO A CG 1 +ATOM 1912 C CD . PRO A 1 271 ? -30.276 -8.621 -47.204 1.00 54.77 ? 333 PRO A CD 1 +ATOM 1913 N N . HIS A 1 272 ? -33.163 -9.530 -47.999 1.00 45.67 ? 334 HIS A N 1 +ATOM 1914 C CA . HIS A 1 272 ? -34.432 -10.196 -47.744 1.00 47.41 ? 334 HIS A CA 1 +ATOM 1915 C C . HIS A 1 272 ? -35.487 -9.288 -47.128 1.00 47.75 ? 334 HIS A C 1 +ATOM 1916 O O . HIS A 1 272 ? -36.680 -9.571 -47.274 1.00 47.29 ? 334 HIS A O 1 +ATOM 1917 C CB . HIS A 1 272 ? -34.238 -11.398 -46.803 1.00 46.61 ? 334 HIS A CB 1 +ATOM 1918 C CG . HIS A 1 272 ? -33.309 -12.447 -47.327 1.00 40.19 ? 334 HIS A CG 1 +ATOM 1919 N ND1 . HIS A 1 272 ? -33.746 -13.534 -48.053 1.00 38.00 ? 334 HIS A ND1 1 +ATOM 1920 C CD2 . HIS A 1 272 ? -31.969 -12.591 -47.206 1.00 39.87 ? 334 HIS A CD2 1 +ATOM 1921 C CE1 . HIS A 1 272 ? -32.714 -14.294 -48.371 1.00 38.00 ? 334 HIS A CE1 1 +ATOM 1922 N NE2 . HIS A 1 272 ? -31.624 -13.744 -47.870 1.00 41.08 ? 334 HIS A NE2 1 +ATOM 1923 N N . LEU A 1 273 ? -35.083 -8.216 -46.453 1.00 46.48 ? 335 LEU A N 1 +ATOM 1924 C CA . LEU A 1 273 ? -36.011 -7.386 -45.694 1.00 46.94 ? 335 LEU A CA 1 +ATOM 1925 C C . LEU A 1 273 ? -36.732 -6.395 -46.601 1.00 49.98 ? 335 LEU A C 1 +ATOM 1926 O O . LEU A 1 273 ? -36.095 -5.630 -47.330 1.00 54.75 ? 335 LEU A O 1 +ATOM 1927 C CB . LEU A 1 273 ? -35.264 -6.632 -44.595 1.00 49.65 ? 335 LEU A CB 1 +ATOM 1928 C CG . LEU A 1 273 ? -34.752 -7.467 -43.424 1.00 45.22 ? 335 LEU A CG 1 +ATOM 1929 C CD1 . LEU A 1 273 ? -35.814 -8.487 -43.034 1.00 38.00 ? 335 LEU A CD1 1 +ATOM 1930 C CD2 . LEU A 1 273 ? -33.403 -8.120 -43.747 1.00 44.47 ? 335 LEU A CD2 1 +ATOM 1931 N N . LEU A 1 274 ? -38.064 -6.407 -46.545 1.00 47.39 ? 336 LEU A N 1 +ATOM 1932 C CA . LEU A 1 274 ? -38.910 -5.481 -47.288 1.00 42.38 ? 336 LEU A CA 1 +ATOM 1933 C C . LEU A 1 274 ? -40.108 -5.107 -46.432 1.00 40.70 ? 336 LEU A C 1 +ATOM 1934 O O . LEU A 1 274 ? -40.743 -5.985 -45.842 1.00 50.89 ? 336 LEU A O 1 +ATOM 1935 C CB . LEU A 1 274 ? -39.401 -6.099 -48.598 1.00 48.81 ? 336 LEU A CB 1 +ATOM 1936 C CG . LEU A 1 274 ? -40.542 -5.343 -49.279 1.00 47.59 ? 336 LEU A CG 1 +ATOM 1937 C CD1 . LEU A 1 274 ? -40.049 -4.045 -49.894 1.00 48.31 ? 336 LEU A CD1 1 +ATOM 1938 C CD2 . LEU A 1 274 ? -41.225 -6.216 -50.309 1.00 44.10 ? 336 LEU A CD2 1 +ATOM 1939 N N . GLU A 1 275 ? -40.450 -3.823 -46.394 1.00 38.00 ? 337 GLU A N 1 +ATOM 1940 C CA . GLU A 1 275 ? -41.560 -3.379 -45.562 1.00 42.41 ? 337 GLU A CA 1 +ATOM 1941 C C . GLU A 1 275 ? -42.832 -3.272 -46.394 1.00 38.00 ? 337 GLU A C 1 +ATOM 1942 O O . GLU A 1 275 ? -42.790 -2.976 -47.588 1.00 38.00 ? 337 GLU A O 1 +ATOM 1943 C CB . GLU A 1 275 ? -41.270 -2.033 -44.885 1.00 51.92 ? 337 GLU A CB 1 +ATOM 1944 C CG . GLU A 1 275 ? -41.122 -0.857 -45.837 1.00 51.39 ? 337 GLU A CG 1 +ATOM 1945 C CD . GLU A 1 275 ? -40.984 0.483 -45.119 1.00 45.74 ? 337 GLU A CD 1 +ATOM 1946 O OE1 . GLU A 1 275 ? -39.967 0.701 -44.421 1.00 44.30 ? 337 GLU A OE1 1 +ATOM 1947 O OE2 . GLU A 1 275 ? -41.913 1.311 -45.242 1.00 38.00 ? 337 GLU A OE2 1 +ATOM 1948 N N . GLY A 1 276 ? -43.965 -3.551 -45.754 1.00 38.00 ? 338 GLY A N 1 +ATOM 1949 C CA . GLY A 1 276 ? -45.245 -3.504 -46.426 1.00 38.00 ? 338 GLY A CA 1 +ATOM 1950 C C . GLY A 1 276 ? -46.354 -3.156 -45.459 1.00 38.00 ? 338 GLY A C 1 +ATOM 1951 O O . GLY A 1 276 ? -46.120 -2.903 -44.276 1.00 38.00 ? 338 GLY A O 1 +ATOM 1952 N N . SER A 1 277 ? -47.578 -3.145 -45.978 1.00 38.00 ? 339 SER A N 1 +ATOM 1953 C CA . SER A 1 277 ? -48.758 -2.785 -45.203 1.00 38.00 ? 339 SER A CA 1 +ATOM 1954 C C . SER A 1 277 ? -49.781 -3.903 -45.299 1.00 38.00 ? 339 SER A C 1 +ATOM 1955 O O . SER A 1 277 ? -50.254 -4.220 -46.394 1.00 38.00 ? 339 SER A O 1 +ATOM 1956 C CB . SER A 1 277 ? -49.360 -1.475 -45.708 1.00 41.01 ? 339 SER A CB 1 +ATOM 1957 O OG . SER A 1 277 ? -49.943 -1.648 -46.988 1.00 40.82 ? 339 SER A OG 1 +ATOM 1958 N N . LEU A 1 278 ? -50.144 -4.476 -44.159 1.00 38.88 ? 340 LEU A N 1 +ATOM 1959 C CA . LEU A 1 278 ? -51.147 -5.531 -44.102 1.00 38.00 ? 340 LEU A CA 1 +ATOM 1960 C C . LEU A 1 278 ? -52.484 -4.920 -43.703 1.00 38.00 ? 340 LEU A C 1 +ATOM 1961 O O . LEU A 1 278 ? -52.593 -4.304 -42.639 1.00 38.06 ? 340 LEU A O 1 +ATOM 1962 C CB . LEU A 1 278 ? -50.740 -6.617 -43.107 1.00 38.00 ? 340 LEU A CB 1 +ATOM 1963 C CG . LEU A 1 278 ? -49.371 -7.246 -43.350 1.00 38.00 ? 340 LEU A CG 1 +ATOM 1964 C CD1 . LEU A 1 278 ? -48.366 -6.817 -42.295 1.00 38.00 ? 340 LEU A CD1 1 +ATOM 1965 C CD2 . LEU A 1 278 ? -49.490 -8.741 -43.407 1.00 43.26 ? 340 LEU A CD2 1 +ATOM 1966 N N . SER A 1 279 ? -53.495 -5.098 -44.544 1.00 38.00 ? 341 SER A N 1 +ATOM 1967 C CA . SER A 1 279 ? -54.829 -4.580 -44.279 1.00 38.00 ? 341 SER A CA 1 +ATOM 1968 C C . SER A 1 279 ? -55.719 -5.748 -43.883 1.00 38.00 ? 341 SER A C 1 +ATOM 1969 O O . SER A 1 279 ? -55.857 -6.705 -44.648 1.00 40.79 ? 341 SER A O 1 +ATOM 1970 C CB . SER A 1 279 ? -55.387 -3.851 -45.503 1.00 40.38 ? 341 SER A CB 1 +ATOM 1971 O OG . SER A 1 279 ? -56.629 -3.227 -45.214 1.00 43.01 ? 341 SER A OG 1 +ATOM 1972 N N . ALA A 1 280 ? -56.307 -5.673 -42.690 1.00 38.00 ? 342 ALA A N 1 +ATOM 1973 C CA . ALA A 1 280 ? -57.097 -6.786 -42.183 1.00 38.00 ? 342 ALA A CA 1 +ATOM 1974 C C . ALA A 1 280 ? -58.223 -7.120 -43.148 1.00 40.30 ? 342 ALA A C 1 +ATOM 1975 O O . ALA A 1 280 ? -58.839 -6.236 -43.748 1.00 42.53 ? 342 ALA A O 1 +ATOM 1976 C CB . ALA A 1 280 ? -57.671 -6.461 -40.806 1.00 38.00 ? 342 ALA A CB 1 +ATOM 1977 N N . PHE A 1 281 ? -58.503 -8.407 -43.276 1.00 42.36 ? 343 PHE A N 1 +ATOM 1978 C CA . PHE A 1 281 ? -59.479 -8.881 -44.240 1.00 39.99 ? 343 PHE A CA 1 +ATOM 1979 C C . PHE A 1 281 ? -60.894 -8.677 -43.728 1.00 38.84 ? 343 PHE A C 1 +ATOM 1980 O O . PHE A 1 281 ? -61.181 -8.888 -42.548 1.00 45.99 ? 343 PHE A O 1 +ATOM 1981 C CB . PHE A 1 281 ? -59.247 -10.359 -44.527 1.00 45.70 ? 343 PHE A CB 1 +ATOM 1982 C CG . PHE A 1 281 ? -58.769 -10.631 -45.909 1.00 48.10 ? 343 PHE A CG 1 +ATOM 1983 C CD1 . PHE A 1 281 ? -57.607 -10.048 -46.379 1.00 42.61 ? 343 PHE A CD1 1 +ATOM 1984 C CD2 . PHE A 1 281 ? -59.478 -11.480 -46.738 1.00 49.42 ? 343 PHE A CD2 1 +ATOM 1985 C CE1 . PHE A 1 281 ? -57.165 -10.302 -47.652 1.00 43.88 ? 343 PHE A CE1 1 +ATOM 1986 C CE2 . PHE A 1 281 ? -59.040 -11.739 -48.009 1.00 51.23 ? 343 PHE A CE2 1 +ATOM 1987 C CZ . PHE A 1 281 ? -57.884 -11.148 -48.470 1.00 49.25 ? 343 PHE A CZ 1 +ATOM 1988 N N . LEU A 1 282 ? -61.777 -8.255 -44.620 1.00 40.12 ? 344 LEU A N 1 +ATOM 1989 C CA . LEU A 1 282 ? -63.182 -8.200 -44.284 1.00 47.06 ? 344 LEU A CA 1 +ATOM 1990 C C . LEU A 1 282 ? -63.740 -9.623 -44.203 1.00 50.77 ? 344 LEU A C 1 +ATOM 1991 O O . LEU A 1 282 ? -63.102 -10.575 -44.663 1.00 45.57 ? 344 LEU A O 1 +ATOM 1992 C CB . LEU A 1 282 ? -63.936 -7.372 -45.319 1.00 50.18 ? 344 LEU A CB 1 +ATOM 1993 C CG . LEU A 1 282 ? -63.517 -5.904 -45.440 1.00 46.39 ? 344 LEU A CG 1 +ATOM 1994 C CD1 . LEU A 1 282 ? -64.404 -5.185 -46.434 1.00 51.38 ? 344 LEU A CD1 1 +ATOM 1995 C CD2 . LEU A 1 282 ? -63.553 -5.207 -44.102 1.00 45.56 ? 344 LEU A CD2 1 +ATOM 1996 N N . PRO A 1 283 ? -64.915 -9.802 -43.592 1.00 52.05 ? 345 PRO A N 1 +ATOM 1997 C CA . PRO A 1 283 ? -65.511 -11.140 -43.531 1.00 51.96 ? 345 PRO A CA 1 +ATOM 1998 C C . PRO A 1 283 ? -65.751 -11.711 -44.920 1.00 61.19 ? 345 PRO A C 1 +ATOM 1999 O O . PRO A 1 283 ? -65.874 -10.986 -45.911 1.00 58.41 ? 345 PRO A O 1 +ATOM 2000 C CB . PRO A 1 283 ? -66.835 -10.908 -42.795 1.00 48.42 ? 345 PRO A CB 1 +ATOM 2001 C CG . PRO A 1 283 ? -66.608 -9.698 -41.991 1.00 46.68 ? 345 PRO A CG 1 +ATOM 2002 C CD . PRO A 1 283 ? -65.705 -8.828 -42.818 1.00 49.20 ? 345 PRO A CD 1 +ATOM 2003 N N . SER A 1 284 ? -65.816 -13.041 -44.975 1.00 71.07 ? 346 SER A N 1 +ATOM 2004 C CA . SER A 1 284 ? -65.987 -13.743 -46.241 1.00 72.25 ? 346 SER A CA 1 +ATOM 2005 C C . SER A 1 284 ? -67.305 -13.364 -46.902 1.00 65.64 ? 346 SER A C 1 +ATOM 2006 O O . SER A 1 284 ? -68.337 -13.224 -46.240 1.00 57.62 ? 346 SER A O 1 +ATOM 2007 C CB . SER A 1 284 ? -65.936 -15.257 -46.022 1.00 75.40 ? 346 SER A CB 1 +ATOM 2008 O OG . SER A 1 284 ? -64.670 -15.664 -45.532 1.00 81.46 ? 346 SER A OG 1 +ATOM 2009 N N . LEU A 1 285 ? -67.268 -13.229 -48.230 1.00 67.63 ? 347 LEU A N 1 +ATOM 2010 C CA . LEU A 1 285 ? -68.457 -12.864 -48.989 1.00 65.32 ? 347 LEU A CA 1 +ATOM 2011 C C . LEU A 1 285 ? -69.538 -13.927 -48.934 1.00 68.75 ? 347 LEU A C 1 +ATOM 2012 O O . LEU A 1 285 ? -70.677 -13.645 -49.321 1.00 62.31 ? 347 LEU A O 1 +ATOM 2013 C CB . LEU A 1 285 ? -68.083 -12.581 -50.442 1.00 55.95 ? 347 LEU A CB 1 +ATOM 2014 C CG . LEU A 1 285 ? -67.279 -11.299 -50.635 1.00 55.81 ? 347 LEU A CG 1 +ATOM 2015 C CD1 . LEU A 1 285 ? -65.895 -11.599 -51.194 1.00 54.10 ? 347 LEU A CD1 1 +ATOM 2016 C CD2 . LEU A 1 285 ? -68.056 -10.336 -51.529 1.00 48.39 ? 347 LEU A CD2 1 +ATOM 2017 N N . ASN A 1 286 ? -69.210 -15.131 -48.462 1.00 80.59 ? 348 ASN A N 1 +ATOM 2018 C CA . ASN A 1 286 ? -70.219 -16.148 -48.207 1.00 83.14 ? 348 ASN A CA 1 +ATOM 2019 C C . ASN A 1 286 ? -70.992 -15.871 -46.926 1.00 83.03 ? 348 ASN A C 1 +ATOM 2020 O O . ASN A 1 286 ? -72.131 -16.334 -46.790 1.00 79.15 ? 348 ASN A O 1 +ATOM 2021 C CB . ASN A 1 286 ? -69.559 -17.529 -48.125 1.00 78.99 ? 348 ASN A CB 1 +ATOM 2022 C CG . ASN A 1 286 ? -68.895 -17.943 -49.429 1.00 78.68 ? 348 ASN A CG 1 +ATOM 2023 O OD1 . ASN A 1 286 ? -69.295 -17.513 -50.511 1.00 79.73 ? 348 ASN A OD1 1 +ATOM 2024 N ND2 . ASN A 1 286 ? -67.863 -18.774 -49.329 1.00 74.58 ? 348 ASN A ND2 1 +ATOM 2025 N N . LEU A 1 287 ? -70.418 -15.086 -46.013 1.00 76.17 ? 349 LEU A N 1 +ATOM 2026 C CA . LEU A 1 287 ? -71.072 -14.714 -44.764 1.00 69.42 ? 349 LEU A CA 1 +ATOM 2027 C C . LEU A 1 287 ? -71.617 -13.293 -44.783 1.00 69.76 ? 349 LEU A C 1 +ATOM 2028 O O . LEU A 1 287 ? -72.663 -13.033 -44.178 1.00 66.25 ? 349 LEU A O 1 +ATOM 2029 C CB . LEU A 1 287 ? -70.092 -14.858 -43.591 1.00 66.70 ? 349 LEU A CB 1 +ATOM 2030 C CG . LEU A 1 287 ? -69.497 -16.244 -43.326 1.00 61.75 ? 349 LEU A CG 1 +ATOM 2031 C CD1 . LEU A 1 287 ? -68.517 -16.226 -42.156 1.00 52.72 ? 349 LEU A CD1 1 +ATOM 2032 C CD2 . LEU A 1 287 ? -70.608 -17.240 -43.069 1.00 67.66 ? 349 LEU A CD2 1 +ATOM 2033 N N . ALA A 1 288 ? -70.947 -12.380 -45.487 1.00 67.83 ? 350 ALA A N 1 +ATOM 2034 C CA . ALA A 1 288 ? -71.359 -10.979 -45.571 1.00 60.81 ? 350 ALA A CA 1 +ATOM 2035 C C . ALA A 1 288 ? -71.134 -10.499 -46.994 1.00 59.81 ? 350 ALA A C 1 +ATOM 2036 O O . ALA A 1 288 ? -70.055 -9.989 -47.328 1.00 53.51 ? 350 ALA A O 1 +ATOM 2037 C CB . ALA A 1 288 ? -70.593 -10.108 -44.577 1.00 64.19 ? 350 ALA A CB 1 +ATOM 2038 N N . PRO A 1 289 ? -72.119 -10.681 -47.876 1.00 62.53 ? 351 PRO A N 1 +ATOM 2039 C CA . PRO A 1 289 ? -71.944 -10.259 -49.271 1.00 63.16 ? 351 PRO A CA 1 +ATOM 2040 C C . PRO A 1 289 ? -71.785 -8.750 -49.385 1.00 61.34 ? 351 PRO A C 1 +ATOM 2041 O O . PRO A 1 289 ? -72.397 -7.974 -48.647 1.00 56.45 ? 351 PRO A O 1 +ATOM 2042 C CB . PRO A 1 289 ? -73.230 -10.739 -49.955 1.00 58.00 ? 351 PRO A CB 1 +ATOM 2043 C CG . PRO A 1 289 ? -73.808 -11.763 -49.030 1.00 54.75 ? 351 PRO A CG 1 +ATOM 2044 C CD . PRO A 1 289 ? -73.421 -11.326 -47.653 1.00 54.77 ? 351 PRO A CD 1 +ATOM 2045 N N . ARG A 1 290 ? -70.995 -8.338 -50.367 1.00 60.56 ? 352 ARG A N 1 +ATOM 2046 C CA . ARG A 1 290 ? -70.710 -6.934 -50.589 1.00 56.84 ? 352 ARG A CA 1 +ATOM 2047 C C . ARG A 1 290 ? -71.121 -6.543 -51.998 1.00 58.71 ? 352 ARG A C 1 +ATOM 2048 O O . ARG A 1 290 ? -71.279 -7.388 -52.882 1.00 69.03 ? 352 ARG A O 1 +ATOM 2049 C CB . ARG A 1 290 ? -69.228 -6.626 -50.371 1.00 48.99 ? 352 ARG A CB 1 +ATOM 2050 C CG . ARG A 1 290 ? -68.766 -6.932 -48.980 1.00 41.37 ? 352 ARG A CG 1 +ATOM 2051 C CD . ARG A 1 290 ? -67.489 -6.208 -48.689 1.00 41.85 ? 352 ARG A CD 1 +ATOM 2052 N NE . ARG A 1 290 ? -66.355 -6.776 -49.403 1.00 43.42 ? 352 ARG A NE 1 +ATOM 2053 C CZ . ARG A 1 290 ? -65.674 -7.829 -48.972 1.00 50.20 ? 352 ARG A CZ 1 +ATOM 2054 N NH1 . ARG A 1 290 ? -66.032 -8.421 -47.840 1.00 49.38 ? 352 ARG A NH1 1 +ATOM 2055 N NH2 . ARG A 1 290 ? -64.643 -8.290 -49.669 1.00 52.18 ? 352 ARG A NH2 1 +ATOM 2056 N N . LEU A 1 291 ? -71.263 -5.239 -52.202 1.00 51.75 ? 353 LEU A N 1 +ATOM 2057 C CA . LEU A 1 291 ? -71.826 -4.693 -53.431 1.00 47.71 ? 353 LEU A CA 1 +ATOM 2058 C C . LEU A 1 291 ? -70.943 -3.538 -53.881 1.00 50.99 ? 353 LEU A C 1 +ATOM 2059 O O . LEU A 1 291 ? -71.014 -2.445 -53.318 1.00 56.59 ? 353 LEU A O 1 +ATOM 2060 C CB . LEU A 1 291 ? -73.265 -4.248 -53.200 1.00 42.10 ? 353 LEU A CB 1 +ATOM 2061 C CG . LEU A 1 291 ? -74.248 -4.426 -54.351 1.00 50.38 ? 353 LEU A CG 1 +ATOM 2062 C CD1 . LEU A 1 291 ? -75.649 -4.070 -53.873 1.00 47.18 ? 353 LEU A CD1 1 +ATOM 2063 C CD2 . LEU A 1 291 ? -73.847 -3.587 -55.573 1.00 42.53 ? 353 LEU A CD2 1 +ATOM 2064 N N . SER A 1 292 ? -70.087 -3.786 -54.866 1.00 51.59 ? 354 SER A N 1 +ATOM 2065 C CA . SER A 1 292 ? -69.281 -2.718 -55.446 1.00 54.33 ? 354 SER A CA 1 +ATOM 2066 C C . SER A 1 292 ? -70.191 -1.795 -56.248 1.00 56.22 ? 354 SER A C 1 +ATOM 2067 O O . SER A 1 292 ? -70.775 -2.205 -57.256 1.00 56.14 ? 354 SER A O 1 +ATOM 2068 C CB . SER A 1 292 ? -68.168 -3.286 -56.321 1.00 61.31 ? 354 SER A CB 1 +ATOM 2069 O OG . SER A 1 292 ? -67.151 -2.323 -56.540 1.00 54.81 ? 354 SER A OG 1 +ATOM 2070 N N . VAL A 1 293 ? -70.357 -0.571 -55.773 1.00 55.04 ? 355 VAL A N 1 +ATOM 2071 C CA . VAL A 1 293 ? -71.203 0.431 -56.414 1.00 54.33 ? 355 VAL A CA 1 +ATOM 2072 C C . VAL A 1 293 ? -70.296 1.452 -57.088 1.00 54.97 ? 355 VAL A C 1 +ATOM 2073 O O . VAL A 1 293 ? -69.316 1.892 -56.475 1.00 48.27 ? 355 VAL A O 1 +ATOM 2074 C CB . VAL A 1 293 ? -72.150 1.116 -55.408 1.00 52.53 ? 355 VAL A CB 1 +ATOM 2075 C CG1 . VAL A 1 293 ? -72.862 2.287 -56.058 1.00 58.44 ? 355 VAL A CG1 1 +ATOM 2076 C CG2 . VAL A 1 293 ? -73.170 0.117 -54.891 1.00 48.17 ? 355 VAL A CG2 1 +ATOM 2077 N N . PRO A 1 294 ? -70.545 1.806 -58.348 1.00 60.57 ? 356 PRO A N 1 +ATOM 2078 C CA . PRO A 1 294 ? -69.748 2.857 -58.986 1.00 59.55 ? 356 PRO A CA 1 +ATOM 2079 C C . PRO A 1 294 ? -70.061 4.225 -58.403 1.00 61.41 ? 356 PRO A C 1 +ATOM 2080 O O . PRO A 1 294 ? -71.222 4.577 -58.171 1.00 58.77 ? 356 PRO A O 1 +ATOM 2081 C CB . PRO A 1 294 ? -70.160 2.771 -60.460 1.00 62.65 ? 356 PRO A CB 1 +ATOM 2082 C CG . PRO A 1 294 ? -71.523 2.167 -60.430 1.00 66.07 ? 356 PRO A CG 1 +ATOM 2083 C CD . PRO A 1 294 ? -71.523 1.211 -59.275 1.00 62.05 ? 356 PRO A CD 1 +ATOM 2084 N N . ASN A 1 295 ? -69.004 4.994 -58.166 1.00 58.05 ? 357 ASN A N 1 +ATOM 2085 C CA . ASN A 1 295 ? -69.157 6.353 -57.684 1.00 55.25 ? 357 ASN A CA 1 +ATOM 2086 C C . ASN A 1 295 ? -69.908 7.200 -58.712 1.00 58.68 ? 357 ASN A C 1 +ATOM 2087 O O . ASN A 1 295 ? -69.800 6.965 -59.916 1.00 65.79 ? 357 ASN A O 1 +ATOM 2088 C CB . ASN A 1 295 ? -67.789 6.967 -57.405 1.00 49.74 ? 357 ASN A CB 1 +ATOM 2089 C CG . ASN A 1 295 ? -67.878 8.230 -56.592 1.00 55.13 ? 357 ASN A CG 1 +ATOM 2090 O OD1 . ASN A 1 295 ? -68.319 9.265 -57.083 1.00 54.69 ? 357 ASN A OD1 1 +ATOM 2091 N ND2 . ASN A 1 295 ? -67.461 8.154 -55.336 1.00 63.48 ? 357 ASN A ND2 1 +ATOM 2092 N N . PRO A 1 296 ? -70.698 8.180 -58.267 1.00 54.36 ? 358 PRO A N 1 +ATOM 2093 C CA . PRO A 1 296 ? -71.240 9.166 -59.213 1.00 54.87 ? 358 PRO A CA 1 +ATOM 2094 C C . PRO A 1 296 ? -70.214 10.179 -59.694 1.00 53.64 ? 358 PRO A C 1 +ATOM 2095 O O . PRO A 1 296 ? -70.463 10.857 -60.699 1.00 58.17 ? 358 PRO A O 1 +ATOM 2096 C CB . PRO A 1 296 ? -72.358 9.848 -58.408 1.00 54.54 ? 358 PRO A CB 1 +ATOM 2097 C CG . PRO A 1 296 ? -72.681 8.894 -57.308 1.00 56.17 ? 358 PRO A CG 1 +ATOM 2098 C CD . PRO A 1 296 ? -71.390 8.221 -56.970 1.00 57.65 ? 358 PRO A CD 1 +ATOM 2099 N N . TRP A 1 297 ? -69.062 10.281 -59.034 1.00 48.09 ? 359 TRP A N 1 +ATOM 2100 C CA . TRP A 1 297 ? -68.026 11.223 -59.436 1.00 50.01 ? 359 TRP A CA 1 +ATOM 2101 C C . TRP A 1 297 ? -66.797 10.473 -59.928 1.00 50.15 ? 359 TRP A C 1 +ATOM 2102 O O . TRP A 1 297 ? -65.676 10.737 -59.477 1.00 45.87 ? 359 TRP A O 1 +ATOM 2103 C CB . TRP A 1 297 ? -67.646 12.160 -58.278 1.00 51.30 ? 359 TRP A CB 1 +ATOM 2104 C CG . TRP A 1 297 ? -68.627 13.277 -58.032 1.00 50.46 ? 359 TRP A CG 1 +ATOM 2105 C CD1 . TRP A 1 297 ? -68.541 14.553 -58.504 1.00 48.72 ? 359 TRP A CD1 1 +ATOM 2106 C CD2 . TRP A 1 297 ? -69.833 13.219 -57.253 1.00 50.74 ? 359 TRP A CD2 1 +ATOM 2107 N NE1 . TRP A 1 297 ? -69.619 15.290 -58.077 1.00 52.49 ? 359 TRP A NE1 1 +ATOM 2108 C CE2 . TRP A 1 297 ? -70.426 14.494 -57.308 1.00 49.47 ? 359 TRP A CE2 1 +ATOM 2109 C CE3 . TRP A 1 297 ? -70.468 12.214 -56.519 1.00 53.18 ? 359 TRP A CE3 1 +ATOM 2110 C CZ2 . TRP A 1 297 ? -71.623 14.789 -56.657 1.00 48.52 ? 359 TRP A CZ2 1 +ATOM 2111 C CZ3 . TRP A 1 297 ? -71.659 12.513 -55.874 1.00 49.45 ? 359 TRP A CZ3 1 +ATOM 2112 C CH2 . TRP A 1 297 ? -72.220 13.787 -55.948 1.00 43.05 ? 359 TRP A CH2 1 +ATOM 2113 N N . ILE A 1 298 ? -66.996 9.515 -60.836 1.00 56.10 ? 360 ILE A N 1 +ATOM 2114 C CA . ILE A 1 298 ? -65.849 8.825 -61.411 1.00 61.12 ? 360 ILE A CA 1 +ATOM 2115 C C . ILE A 1 298 ? -65.048 9.792 -62.274 1.00 57.97 ? 360 ILE A C 1 +ATOM 2116 O O . ILE A 1 298 ? -65.537 10.836 -62.721 1.00 58.92 ? 360 ILE A O 1 +ATOM 2117 C CB . ILE A 1 298 ? -66.254 7.585 -62.225 1.00 57.91 ? 360 ILE A CB 1 +ATOM 2118 C CG1 . ILE A 1 298 ? -67.699 7.174 -61.944 1.00 53.22 ? 360 ILE A CG1 1 +ATOM 2119 C CG2 . ILE A 1 298 ? -65.292 6.438 -61.936 1.00 48.91 ? 360 ILE A CG2 1 +ATOM 2120 C CD1 . ILE A 1 298 ? -68.738 7.813 -62.864 1.00 51.63 ? 360 ILE A CD1 1 +ATOM 2121 N N . ARG A 1 299 ? -63.797 9.431 -62.512 1.00 59.71 ? 361 ARG A N 1 +ATOM 2122 C CA . ARG A 1 299 ? -62.981 10.135 -63.481 1.00 65.25 ? 361 ARG A CA 1 +ATOM 2123 C C . ARG A 1 299 ? -63.116 9.481 -64.856 1.00 68.41 ? 361 ARG A C 1 +ATOM 2124 O O . ARG A 1 299 ? -63.667 8.388 -65.007 1.00 69.82 ? 361 ARG A O 1 +ATOM 2125 C CB . ARG A 1 299 ? -61.525 10.157 -63.035 1.00 60.37 ? 361 ARG A CB 1 +ATOM 2126 C CG . ARG A 1 299 ? -61.046 11.514 -62.597 1.00 58.71 ? 361 ARG A CG 1 +ATOM 2127 C CD . ARG A 1 299 ? -61.020 11.637 -61.094 1.00 59.50 ? 361 ARG A CD 1 +ATOM 2128 N NE . ARG A 1 299 ? -60.335 12.863 -60.699 1.00 68.58 ? 361 ARG A NE 1 +ATOM 2129 C CZ . ARG A 1 299 ? -60.199 13.281 -59.446 1.00 62.38 ? 361 ARG A CZ 1 +ATOM 2130 N NH1 . ARG A 1 299 ? -60.705 12.569 -58.446 1.00 63.32 ? 361 ARG A NH1 1 +ATOM 2131 N NH2 . ARG A 1 299 ? -59.552 14.413 -59.195 1.00 49.50 ? 361 ARG A NH2 1 +ATOM 2132 N N . SER A 1 300 ? -62.630 10.188 -65.879 1.00 61.88 ? 362 SER A N 1 +ATOM 2133 C CA . SER A 1 300 ? -62.667 9.641 -67.231 1.00 65.25 ? 362 SER A CA 1 +ATOM 2134 C C . SER A 1 300 ? -61.738 8.438 -67.380 1.00 65.61 ? 362 SER A C 1 +ATOM 2135 O O . SER A 1 300 ? -62.006 7.549 -68.197 1.00 57.24 ? 362 SER A O 1 +ATOM 2136 C CB . SER A 1 300 ? -62.315 10.731 -68.244 1.00 70.20 ? 362 SER A CB 1 +ATOM 2137 O OG . SER A 1 300 ? -61.022 11.265 -68.013 1.00 62.86 ? 362 SER A OG 1 +ATOM 2138 N N . TYR A 1 301 ? -60.642 8.405 -66.615 1.00 66.15 ? 363 TYR A N 1 +ATOM 2139 C CA . TYR A 1 301 ? -59.606 7.371 -66.719 1.00 59.16 ? 363 TYR A CA 1 +ATOM 2140 C C . TYR A 1 301 ? -59.099 7.261 -68.152 1.00 57.36 ? 363 TYR A C 1 +ATOM 2141 O O . TYR A 1 301 ? -58.946 6.173 -68.708 1.00 57.39 ? 363 TYR A O 1 +ATOM 2142 C CB . TYR A 1 301 ? -60.098 6.022 -66.194 1.00 54.68 ? 363 TYR A CB 1 +ATOM 2143 C CG . TYR A 1 301 ? -60.241 6.009 -64.691 1.00 61.81 ? 363 TYR A CG 1 +ATOM 2144 C CD1 . TYR A 1 301 ? -59.139 5.803 -63.867 1.00 60.57 ? 363 TYR A CD1 1 +ATOM 2145 C CD2 . TYR A 1 301 ? -61.478 6.209 -64.093 1.00 63.82 ? 363 TYR A CD2 1 +ATOM 2146 C CE1 . TYR A 1 301 ? -59.269 5.803 -62.486 1.00 58.80 ? 363 TYR A CE1 1 +ATOM 2147 C CE2 . TYR A 1 301 ? -61.619 6.205 -62.721 1.00 62.75 ? 363 TYR A CE2 1 +ATOM 2148 C CZ . TYR A 1 301 ? -60.515 6.004 -61.922 1.00 63.28 ? 363 TYR A CZ 1 +ATOM 2149 O OH . TYR A 1 301 ? -60.664 6.003 -60.554 1.00 62.83 ? 363 TYR A OH 1 +ATOM 2150 N N . THR A 1 302 ? -58.828 8.422 -68.740 1.00 57.77 ? 364 THR A N 1 +ATOM 2151 C CA . THR A 1 302 ? -58.294 8.534 -70.084 1.00 54.98 ? 364 THR A CA 1 +ATOM 2152 C C . THR A 1 302 ? -57.261 9.647 -70.092 1.00 61.51 ? 364 THR A C 1 +ATOM 2153 O O . THR A 1 302 ? -57.183 10.454 -69.161 1.00 64.16 ? 364 THR A O 1 +ATOM 2154 C CB . THR A 1 302 ? -59.387 8.843 -71.113 1.00 49.50 ? 364 THR A CB 1 +ATOM 2155 O OG1 . THR A 1 302 ? -60.664 8.483 -70.575 1.00 39.33 ? 364 THR A OG1 1 +ATOM 2156 C CG2 . THR A 1 302 ? -59.133 8.078 -72.412 1.00 49.80 ? 364 THR A CG2 1 +ATOM 2157 N N . LEU A 1 303 ? -56.454 9.675 -71.153 1.00 60.73 ? 365 LEU A N 1 +ATOM 2158 C CA . LEU A 1 303 ? -55.480 10.750 -71.309 1.00 67.49 ? 365 LEU A CA 1 +ATOM 2159 C C . LEU A 1 303 ? -56.131 12.108 -71.576 1.00 66.15 ? 365 LEU A C 1 +ATOM 2160 O O . LEU A 1 303 ? -55.455 13.137 -71.460 1.00 61.17 ? 365 LEU A O 1 +ATOM 2161 C CB . LEU A 1 303 ? -54.493 10.396 -72.423 1.00 65.22 ? 365 LEU A CB 1 +ATOM 2162 C CG . LEU A 1 303 ? -53.627 9.162 -72.148 1.00 56.73 ? 365 LEU A CG 1 +ATOM 2163 C CD1 . LEU A 1 303 ? -52.689 8.868 -73.310 1.00 60.66 ? 365 LEU A CD1 1 +ATOM 2164 C CD2 . LEU A 1 303 ? -52.842 9.348 -70.867 1.00 52.66 ? 365 LEU A CD2 1 +ATOM 2165 N N . ALA A 1 304 ? -57.419 12.137 -71.908 1.00 58.56 ? 366 ALA A N 1 +ATOM 2166 C CA . ALA A 1 304 ? -58.156 13.374 -72.106 1.00 49.78 ? 366 ALA A CA 1 +ATOM 2167 C C . ALA A 1 304 ? -59.619 13.100 -71.782 1.00 55.00 ? 366 ALA A C 1 +ATOM 2168 O O . ALA A 1 304 ? -59.989 11.995 -71.374 1.00 54.45 ? 366 ALA A O 1 +ATOM 2169 C CB . ALA A 1 304 ? -57.968 13.910 -73.528 1.00 52.99 ? 366 ALA A CB 1 +ATOM 2170 N N . GLY A 1 305 ? -60.453 14.121 -71.939 1.00 54.40 ? 367 GLY A N 1 +ATOM 2171 C CA . GLY A 1 305 ? -61.864 13.941 -71.671 1.00 54.56 ? 367 GLY A CA 1 +ATOM 2172 C C . GLY A 1 305 ? -62.206 14.096 -70.205 1.00 61.85 ? 367 GLY A C 1 +ATOM 2173 O O . GLY A 1 305 ? -61.495 13.596 -69.328 1.00 58.38 ? 367 GLY A O 1 +ATOM 2174 N N . LYS A 1 306 ? -63.288 14.817 -69.934 1.00 68.80 ? 368 LYS A N 1 +ATOM 2175 C CA . LYS A 1 306 ? -63.766 15.054 -68.583 1.00 64.51 ? 368 LYS A CA 1 +ATOM 2176 C C . LYS A 1 306 ? -65.171 14.490 -68.431 1.00 63.30 ? 368 LYS A C 1 +ATOM 2177 O O . LYS A 1 306 ? -65.921 14.375 -69.406 1.00 57.78 ? 368 LYS A O 1 +ATOM 2178 C CB . LYS A 1 306 ? -63.775 16.554 -68.227 1.00 70.42 ? 368 LYS A CB 1 +ATOM 2179 C CG . LYS A 1 306 ? -63.390 17.506 -69.358 1.00 75.54 ? 368 LYS A CG 1 +ATOM 2180 C CD . LYS A 1 306 ? -61.872 17.686 -69.470 1.00 70.04 ? 368 LYS A CD 1 +ATOM 2181 C CE . LYS A 1 306 ? -61.270 18.241 -68.183 1.00 68.05 ? 368 LYS A CE 1 +ATOM 2182 N NZ . LYS A 1 306 ? -59.792 18.426 -68.285 1.00 69.17 ? 368 LYS A NZ 1 +ATOM 2183 N N . GLU A 1 307 ? -65.517 14.138 -67.197 1.00 63.98 ? 369 GLU A N 1 +ATOM 2184 C CA . GLU A 1 307 ? -66.851 13.648 -66.901 1.00 62.46 ? 369 GLU A CA 1 +ATOM 2185 C C . GLU A 1 307 ? -67.824 14.821 -66.764 1.00 61.24 ? 369 GLU A C 1 +ATOM 2186 O O . GLU A 1 307 ? -67.443 15.995 -66.819 1.00 57.92 ? 369 GLU A O 1 +ATOM 2187 C CB . GLU A 1 307 ? -66.826 12.782 -65.644 1.00 60.21 ? 369 GLU A CB 1 +ATOM 2188 C CG . GLU A 1 307 ? -66.152 11.433 -65.840 1.00 66.81 ? 369 GLU A CG 1 +ATOM 2189 C CD . GLU A 1 307 ? -66.950 10.501 -66.740 1.00 77.74 ? 369 GLU A CD 1 +ATOM 2190 O OE1 . GLU A 1 307 ? -68.185 10.681 -66.841 1.00 77.03 ? 369 GLU A OE1 1 +ATOM 2191 O OE2 . GLU A 1 307 ? -66.341 9.589 -67.345 1.00 72.44 ? 369 GLU A OE2 1 +ATOM 2192 N N . GLU A 1 308 ? -69.106 14.489 -66.577 1.00 60.62 ? 370 GLU A N 1 +ATOM 2193 C CA . GLU A 1 308 ? -70.147 15.513 -66.526 1.00 60.91 ? 370 GLU A CA 1 +ATOM 2194 C C . GLU A 1 308 ? -69.963 16.435 -65.326 1.00 56.61 ? 370 GLU A C 1 +ATOM 2195 O O . GLU A 1 308 ? -70.116 17.657 -65.444 1.00 50.59 ? 370 GLU A O 1 +ATOM 2196 C CB . GLU A 1 308 ? -71.525 14.848 -66.491 1.00 67.91 ? 370 GLU A CB 1 +ATOM 2197 C CG . GLU A 1 308 ? -72.563 15.497 -67.403 1.00 76.98 ? 370 GLU A CG 1 +ATOM 2198 C CD . GLU A 1 308 ? -73.593 16.331 -66.651 1.00 80.16 ? 370 GLU A CD 1 +ATOM 2199 O OE1 . GLU A 1 308 ? -74.244 15.795 -65.724 1.00 79.32 ? 370 GLU A OE1 1 +ATOM 2200 O OE2 . GLU A 1 308 ? -73.754 17.523 -66.991 1.00 76.05 ? 370 GLU A OE2 1 +ATOM 2201 N N . TRP A 1 309 ? -69.644 15.863 -64.158 1.00 62.61 ? 371 TRP A N 1 +ATOM 2202 C CA . TRP A 1 309 ? -69.429 16.659 -62.952 1.00 57.90 ? 371 TRP A CA 1 +ATOM 2203 C C . TRP A 1 309 ? -68.219 17.575 -63.082 1.00 59.56 ? 371 TRP A C 1 +ATOM 2204 O O . TRP A 1 309 ? -68.145 18.604 -62.400 1.00 59.79 ? 371 TRP A O 1 +ATOM 2205 C CB . TRP A 1 309 ? -69.246 15.748 -61.738 1.00 51.77 ? 371 TRP A CB 1 +ATOM 2206 C CG . TRP A 1 309 ? -68.019 14.888 -61.814 1.00 52.35 ? 371 TRP A CG 1 +ATOM 2207 C CD1 . TRP A 1 309 ? -67.941 13.621 -62.309 1.00 52.90 ? 371 TRP A CD1 1 +ATOM 2208 C CD2 . TRP A 1 309 ? -66.691 15.238 -61.393 1.00 50.04 ? 371 TRP A CD2 1 +ATOM 2209 N NE1 . TRP A 1 309 ? -66.649 13.158 -62.219 1.00 57.25 ? 371 TRP A NE1 1 +ATOM 2210 C CE2 . TRP A 1 309 ? -65.863 14.132 -61.660 1.00 53.93 ? 371 TRP A CE2 1 +ATOM 2211 C CE3 . TRP A 1 309 ? -66.124 16.377 -60.813 1.00 51.84 ? 371 TRP A CE3 1 +ATOM 2212 C CZ2 . TRP A 1 309 ? -64.497 14.129 -61.366 1.00 54.46 ? 371 TRP A CZ2 1 +ATOM 2213 C CZ3 . TRP A 1 309 ? -64.768 16.372 -60.523 1.00 52.99 ? 371 TRP A CZ3 1 +ATOM 2214 C CH2 . TRP A 1 309 ? -63.971 15.255 -60.799 1.00 48.17 ? 371 TRP A CH2 1 +ATOM 2215 N N . GLU A 1 310 ? -67.245 17.204 -63.916 1.00 52.90 ? 372 GLU A N 1 +ATOM 2216 C CA . GLU A 1 310 ? -66.067 18.042 -64.084 1.00 48.77 ? 372 GLU A CA 1 +ATOM 2217 C C . GLU A 1 310 ? -66.366 19.346 -64.808 1.00 58.41 ? 372 GLU A C 1 +ATOM 2218 O O . GLU A 1 310 ? -65.550 20.270 -64.733 1.00 58.55 ? 372 GLU A O 1 +ATOM 2219 C CB . GLU A 1 310 ? -64.973 17.283 -64.835 1.00 52.47 ? 372 GLU A CB 1 +ATOM 2220 C CG . GLU A 1 310 ? -63.862 16.768 -63.936 1.00 59.38 ? 372 GLU A CG 1 +ATOM 2221 C CD . GLU A 1 310 ? -62.906 15.820 -64.637 1.00 55.46 ? 372 GLU A CD 1 +ATOM 2222 O OE1 . GLU A 1 310 ? -63.383 14.890 -65.325 1.00 55.75 ? 372 GLU A OE1 1 +ATOM 2223 O OE2 . GLU A 1 310 ? -61.677 16.008 -64.490 1.00 38.00 ? 372 GLU A OE2 1 +ATOM 2224 N N . VAL A 1 311 ? -67.518 19.460 -65.472 1.00 63.38 ? 373 VAL A N 1 +ATOM 2225 C CA . VAL A 1 311 ? -67.805 20.622 -66.308 1.00 58.59 ? 373 VAL A CA 1 +ATOM 2226 C C . VAL A 1 311 ? -69.069 21.339 -65.843 1.00 53.91 ? 373 VAL A C 1 +ATOM 2227 O O . VAL A 1 311 ? -69.175 22.564 -65.962 1.00 53.97 ? 373 VAL A O 1 +ATOM 2228 C CB . VAL A 1 311 ? -67.923 20.211 -67.788 1.00 58.81 ? 373 VAL A CB 1 +ATOM 2229 C CG1 . VAL A 1 311 ? -68.065 21.443 -68.676 1.00 63.42 ? 373 VAL A CG1 1 +ATOM 2230 C CG2 . VAL A 1 311 ? -66.721 19.360 -68.214 1.00 50.94 ? 373 VAL A CG2 1 +ATOM 2231 N N . ASN A 1 312 ? -70.033 20.591 -65.300 1.00 52.02 ? 374 ASN A N 1 +ATOM 2232 C CA . ASN A 1 312 ? -71.311 21.163 -64.899 1.00 53.76 ? 374 ASN A CA 1 +ATOM 2233 C C . ASN A 1 312 ? -71.328 21.384 -63.393 1.00 66.58 ? 374 ASN A C 1 +ATOM 2234 O O . ASN A 1 312 ? -71.386 20.402 -62.637 1.00 69.38 ? 374 ASN A O 1 +ATOM 2235 C CB . ASN A 1 312 ? -72.468 20.253 -65.315 1.00 53.15 ? 374 ASN A CB 1 +ATOM 2236 C CG . ASN A 1 312 ? -73.820 20.743 -64.804 1.00 57.99 ? 374 ASN A CG 1 +ATOM 2237 O OD1 . ASN A 1 312 ? -73.985 21.912 -64.453 1.00 59.19 ? 374 ASN A OD1 1 +ATOM 2238 N ND2 . ASN A 1 312 ? -74.797 19.841 -64.765 1.00 54.81 ? 374 ASN A ND2 1 +ATOM 2239 N N . PRO A 1 313 ? -71.278 22.630 -62.907 1.00 67.73 ? 375 PRO A N 1 +ATOM 2240 C CA . PRO A 1 313 ? -71.384 22.858 -61.457 1.00 61.97 ? 375 PRO A CA 1 +ATOM 2241 C C . PRO A 1 313 ? -72.730 22.467 -60.874 1.00 57.29 ? 375 PRO A C 1 +ATOM 2242 O O . PRO A 1 313 ? -72.840 22.354 -59.647 1.00 59.44 ? 375 PRO A O 1 +ATOM 2243 C CB . PRO A 1 313 ? -71.141 24.368 -61.316 1.00 64.03 ? 375 PRO A CB 1 +ATOM 2244 C CG . PRO A 1 313 ? -70.493 24.791 -62.592 1.00 61.48 ? 375 PRO A CG 1 +ATOM 2245 C CD . PRO A 1 313 ? -71.030 23.879 -63.646 1.00 65.13 ? 375 PRO A CD 1 +ATOM 2246 N N . LEU A 1 314 ? -73.750 22.243 -61.703 1.00 52.50 ? 376 LEU A N 1 +ATOM 2247 C CA . LEU A 1 314 ? -75.060 21.806 -61.237 1.00 62.76 ? 376 LEU A CA 1 +ATOM 2248 C C . LEU A 1 314 ? -75.219 20.294 -61.314 1.00 70.06 ? 376 LEU A C 1 +ATOM 2249 O O . LEU A 1 314 ? -76.342 19.792 -61.443 1.00 72.12 ? 376 LEU A O 1 +ATOM 2250 C CB . LEU A 1 314 ? -76.165 22.488 -62.040 1.00 63.30 ? 376 LEU A CB 1 +ATOM 2251 C CG . LEU A 1 314 ? -76.246 24.009 -61.952 1.00 72.98 ? 376 LEU A CG 1 +ATOM 2252 C CD1 . LEU A 1 314 ? -77.189 24.537 -63.017 1.00 75.82 ? 376 LEU A CD1 1 +ATOM 2253 C CD2 . LEU A 1 314 ? -76.704 24.437 -60.566 1.00 69.59 ? 376 LEU A CD2 1 +ATOM 2254 N N . TYR A 1 315 ? -74.108 19.559 -61.223 1.00 70.17 ? 377 TYR A N 1 +ATOM 2255 C CA . TYR A 1 315 ? -74.155 18.108 -61.381 1.00 69.92 ? 377 TYR A CA 1 +ATOM 2256 C C . TYR A 1 315 ? -74.984 17.452 -60.284 1.00 70.17 ? 377 TYR A C 1 +ATOM 2257 O O . TYR A 1 315 ? -75.751 16.519 -60.553 1.00 64.53 ? 377 TYR A O 1 +ATOM 2258 C CB . TYR A 1 315 ? -72.733 17.542 -61.392 1.00 64.64 ? 377 TYR A CB 1 +ATOM 2259 C CG . TYR A 1 315 ? -72.657 16.044 -61.599 1.00 66.51 ? 377 TYR A CG 1 +ATOM 2260 C CD1 . TYR A 1 315 ? -72.889 15.486 -62.849 1.00 68.83 ? 377 TYR A CD1 1 +ATOM 2261 C CD2 . TYR A 1 315 ? -72.343 15.189 -60.550 1.00 64.43 ? 377 TYR A CD2 1 +ATOM 2262 C CE1 . TYR A 1 315 ? -72.818 14.120 -63.048 1.00 70.18 ? 377 TYR A CE1 1 +ATOM 2263 C CE2 . TYR A 1 315 ? -72.263 13.822 -60.740 1.00 61.56 ? 377 TYR A CE2 1 +ATOM 2264 C CZ . TYR A 1 315 ? -72.505 13.292 -61.990 1.00 67.17 ? 377 TYR A CZ 1 +ATOM 2265 O OH . TYR A 1 315 ? -72.433 11.930 -62.183 1.00 76.94 ? 377 TYR A OH 1 +ATOM 2266 N N . CYS A 1 316 ? -74.858 17.937 -59.045 1.00 70.46 ? 378 CYS A N 1 +ATOM 2267 C CA . CYS A 1 316 ? -75.555 17.308 -57.927 1.00 75.86 ? 378 CYS A CA 1 +ATOM 2268 C C . CYS A 1 316 ? -77.058 17.550 -57.959 1.00 74.00 ? 378 CYS A C 1 +ATOM 2269 O O . CYS A 1 316 ? -77.806 16.790 -57.335 1.00 71.57 ? 378 CYS A O 1 +ATOM 2270 C CB . CYS A 1 316 ? -74.977 17.791 -56.593 1.00 72.18 ? 378 CYS A CB 1 +ATOM 2271 S SG . CYS A 1 316 ? -75.561 16.839 -55.146 1.00 74.61 ? 378 CYS A SG 1 +ATOM 2272 N N . ASP A 1 317 ? -77.520 18.586 -58.659 1.00 75.00 ? 379 ASP A N 1 +ATOM 2273 C CA . ASP A 1 317 ? -78.959 18.759 -58.819 1.00 76.19 ? 379 ASP A CA 1 +ATOM 2274 C C . ASP A 1 317 ? -79.578 17.579 -59.555 1.00 77.49 ? 379 ASP A C 1 +ATOM 2275 O O . ASP A 1 317 ? -80.732 17.218 -59.294 1.00 73.86 ? 379 ASP A O 1 +ATOM 2276 C CB . ASP A 1 317 ? -79.242 20.070 -59.547 1.00 78.52 ? 379 ASP A CB 1 +ATOM 2277 C CG . ASP A 1 317 ? -79.029 21.276 -58.659 1.00 78.99 ? 379 ASP A CG 1 +ATOM 2278 O OD1 . ASP A 1 317 ? -79.196 21.141 -57.428 1.00 69.52 ? 379 ASP A OD1 1 +ATOM 2279 O OD2 . ASP A 1 317 ? -78.676 22.350 -59.187 1.00 83.08 ? 379 ASP A OD2 1 +ATOM 2280 N N . THR A 1 318 ? -78.816 16.949 -60.451 1.00 73.87 ? 380 THR A N 1 +ATOM 2281 C CA . THR A 1 318 ? -79.282 15.727 -61.093 1.00 72.51 ? 380 THR A CA 1 +ATOM 2282 C C . THR A 1 318 ? -79.131 14.533 -60.161 1.00 71.17 ? 380 THR A C 1 +ATOM 2283 O O . THR A 1 318 ? -80.037 13.698 -60.065 1.00 68.70 ? 380 THR A O 1 +ATOM 2284 C CB . THR A 1 318 ? -78.506 15.484 -62.389 1.00 74.98 ? 380 THR A CB 1 +ATOM 2285 O OG1 . THR A 1 318 ? -78.554 16.659 -63.204 1.00 94.26 ? 380 THR A OG1 1 +ATOM 2286 C CG2 . THR A 1 318 ? -79.112 14.321 -63.163 1.00 71.76 ? 380 THR A CG2 1 +ATOM 2287 N N . VAL A 1 319 ? -78.009 14.468 -59.435 1.00 67.85 ? 381 VAL A N 1 +ATOM 2288 C CA . VAL A 1 319 ? -77.724 13.311 -58.588 1.00 62.06 ? 381 VAL A CA 1 +ATOM 2289 C C . VAL A 1 319 ? -78.779 13.176 -57.502 1.00 63.35 ? 381 VAL A C 1 +ATOM 2290 O O . VAL A 1 319 ? -79.198 12.064 -57.157 1.00 64.36 ? 381 VAL A O 1 +ATOM 2291 C CB . VAL A 1 319 ? -76.310 13.423 -57.983 1.00 56.30 ? 381 VAL A CB 1 +ATOM 2292 C CG1 . VAL A 1 319 ? -75.968 12.169 -57.193 1.00 52.82 ? 381 VAL A CG1 1 +ATOM 2293 C CG2 . VAL A 1 319 ? -75.277 13.685 -59.060 1.00 59.41 ? 381 VAL A CG2 1 +ATOM 2294 N N . LYS A 1 320 ? -79.226 14.304 -56.946 1.00 67.33 ? 382 LYS A N 1 +ATOM 2295 C CA . LYS A 1 320 ? -80.210 14.290 -55.871 1.00 65.12 ? 382 LYS A CA 1 +ATOM 2296 C C . LYS A 1 320 ? -81.552 13.710 -56.299 1.00 70.73 ? 382 LYS A C 1 +ATOM 2297 O O . LYS A 1 320 ? -82.392 13.440 -55.434 1.00 74.83 ? 382 LYS A O 1 +ATOM 2298 C CB . LYS A 1 320 ? -80.412 15.705 -55.321 1.00 62.74 ? 382 LYS A CB 1 +ATOM 2299 C CG . LYS A 1 320 ? -79.195 16.271 -54.601 1.00 62.42 ? 382 LYS A CG 1 +ATOM 2300 C CD . LYS A 1 320 ? -79.472 17.650 -54.018 1.00 56.91 ? 382 LYS A CD 1 +ATOM 2301 C CE . LYS A 1 320 ? -78.242 18.205 -53.315 1.00 55.13 ? 382 LYS A CE 1 +ATOM 2302 N NZ . LYS A 1 320 ? -78.492 19.540 -52.710 1.00 53.97 ? 382 LYS A NZ 1 +ATOM 2303 N N . GLN A 1 321 ? -81.782 13.518 -57.598 1.00 66.65 ? 383 GLN A N 1 +ATOM 2304 C CA . GLN A 1 321 ? -83.054 13.011 -58.094 1.00 69.54 ? 383 GLN A CA 1 +ATOM 2305 C C . GLN A 1 321 ? -82.940 11.609 -58.688 1.00 72.41 ? 383 GLN A C 1 +ATOM 2306 O O . GLN A 1 321 ? -83.856 11.157 -59.384 1.00 70.21 ? 383 GLN A O 1 +ATOM 2307 C CB . GLN A 1 321 ? -83.623 13.988 -59.122 1.00 81.54 ? 383 GLN A CB 1 +ATOM 2308 C CG . GLN A 1 321 ? -83.791 15.403 -58.581 1.00 81.75 ? 383 GLN A CG 1 +ATOM 2309 C CD . GLN A 1 321 ? -84.234 16.392 -59.642 1.00 90.56 ? 383 GLN A CD 1 +ATOM 2310 O OE1 . GLN A 1 321 ? -83.944 16.225 -60.831 1.00 87.17 ? 383 GLN A OE1 1 +ATOM 2311 N NE2 . GLN A 1 321 ? -84.956 17.425 -59.217 1.00 85.15 ? 383 GLN A NE2 1 +ATOM 2312 N N . ILE A 1 322 ? -81.849 10.900 -58.403 1.00 78.72 ? 384 ILE A N 1 +ATOM 2313 C CA . ILE A 1 322 ? -81.608 9.554 -58.914 1.00 75.81 ? 384 ILE A CA 1 +ATOM 2314 C C . ILE A 1 322 ? -81.529 8.598 -57.729 1.00 80.41 ? 384 ILE A C 1 +ATOM 2315 O O . ILE A 1 322 ? -80.788 8.846 -56.770 1.00 84.06 ? 384 ILE A O 1 +ATOM 2316 C CB . ILE A 1 322 ? -80.324 9.497 -59.770 1.00 61.38 ? 384 ILE A CB 1 +ATOM 2317 C CG1 . ILE A 1 322 ? -80.636 9.716 -61.255 1.00 63.14 ? 384 ILE A CG1 1 +ATOM 2318 C CG2 . ILE A 1 322 ? -79.596 8.170 -59.601 1.00 56.60 ? 384 ILE A CG2 1 +ATOM 2319 C CD1 . ILE A 1 322 ? -81.138 11.101 -61.614 1.00 60.55 ? 384 ILE A CD1 1 +ATOM 2320 N N . TYR A 1 323 ? -82.300 7.519 -57.791 1.00 75.65 ? 385 TYR A N 1 +ATOM 2321 C CA . TYR A 1 323 ? -82.243 6.493 -56.760 1.00 78.38 ? 385 TYR A CA 1 +ATOM 2322 C C . TYR A 1 323 ? -80.889 5.783 -56.817 1.00 79.80 ? 385 TYR A C 1 +ATOM 2323 O O . TYR A 1 323 ? -80.330 5.599 -57.903 1.00 78.17 ? 385 TYR A O 1 +ATOM 2324 C CB . TYR A 1 323 ? -83.395 5.504 -56.959 1.00 77.78 ? 385 TYR A CB 1 +ATOM 2325 C CG . TYR A 1 323 ? -83.398 4.302 -56.045 1.00 84.35 ? 385 TYR A CG 1 +ATOM 2326 C CD1 . TYR A 1 323 ? -84.053 4.331 -54.820 1.00 82.63 ? 385 TYR A CD1 1 +ATOM 2327 C CD2 . TYR A 1 323 ? -82.749 3.130 -56.415 1.00 92.17 ? 385 TYR A CD2 1 +ATOM 2328 C CE1 . TYR A 1 323 ? -84.056 3.222 -53.986 1.00 90.13 ? 385 TYR A CE1 1 +ATOM 2329 C CE2 . TYR A 1 323 ? -82.745 2.023 -55.592 1.00 94.55 ? 385 TYR A CE2 1 +ATOM 2330 C CZ . TYR A 1 323 ? -83.400 2.072 -54.381 1.00 96.62 ? 385 TYR A CZ 1 +ATOM 2331 O OH . TYR A 1 323 ? -83.393 0.963 -53.566 1.00 102.02 ? 385 TYR A OH 1 +ATOM 2332 N N . PRO A 1 324 ? -80.314 5.393 -55.664 1.00 81.74 ? 386 PRO A N 1 +ATOM 2333 C CA . PRO A 1 324 ? -80.849 5.546 -54.310 1.00 87.60 ? 386 PRO A CA 1 +ATOM 2334 C C . PRO A 1 324 ? -80.349 6.795 -53.586 1.00 87.11 ? 386 PRO A C 1 +ATOM 2335 O O . PRO A 1 324 ? -80.301 6.805 -52.355 1.00 89.55 ? 386 PRO A O 1 +ATOM 2336 C CB . PRO A 1 324 ? -80.345 4.283 -53.612 1.00 89.56 ? 386 PRO A CB 1 +ATOM 2337 C CG . PRO A 1 324 ? -78.998 4.067 -54.230 1.00 82.79 ? 386 PRO A CG 1 +ATOM 2338 C CD . PRO A 1 324 ? -79.093 4.565 -55.664 1.00 78.68 ? 386 PRO A CD 1 +ATOM 2339 N N . TYR A 1 325 ? -79.977 7.827 -54.340 1.00 80.45 ? 387 TYR A N 1 +ATOM 2340 C CA . TYR A 1 325 ? -79.545 9.090 -53.759 1.00 73.19 ? 387 TYR A CA 1 +ATOM 2341 C C . TYR A 1 325 ? -80.708 10.036 -53.494 1.00 75.82 ? 387 TYR A C 1 +ATOM 2342 O O . TYR A 1 325 ? -80.486 11.160 -53.031 1.00 69.06 ? 387 TYR A O 1 +ATOM 2343 C CB . TYR A 1 325 ? -78.511 9.754 -54.671 1.00 58.95 ? 387 TYR A CB 1 +ATOM 2344 C CG . TYR A 1 325 ? -77.358 8.838 -55.015 1.00 63.53 ? 387 TYR A CG 1 +ATOM 2345 C CD1 . TYR A 1 325 ? -77.436 7.968 -56.093 1.00 72.72 ? 387 TYR A CD1 1 +ATOM 2346 C CD2 . TYR A 1 325 ? -76.192 8.839 -54.260 1.00 69.10 ? 387 TYR A CD2 1 +ATOM 2347 C CE1 . TYR A 1 325 ? -76.385 7.123 -56.411 1.00 77.77 ? 387 TYR A CE1 1 +ATOM 2348 C CE2 . TYR A 1 325 ? -75.132 7.997 -54.571 1.00 72.53 ? 387 TYR A CE2 1 +ATOM 2349 C CZ . TYR A 1 325 ? -75.235 7.141 -55.651 1.00 75.09 ? 387 TYR A CZ 1 +ATOM 2350 O OH . TYR A 1 325 ? -74.193 6.297 -55.980 1.00 65.98 ? 387 TYR A OH 1 +ATOM 2351 N N . ASN A 1 326 ? -81.942 9.592 -53.759 1.00 80.20 ? 388 ASN A N 1 +ATOM 2352 C CA . ASN A 1 326 ? -83.133 10.384 -53.482 1.00 79.73 ? 388 ASN A CA 1 +ATOM 2353 C C . ASN A 1 326 ? -83.488 10.407 -52.002 1.00 82.97 ? 388 ASN A C 1 +ATOM 2354 O O . ASN A 1 326 ? -84.154 11.348 -51.556 1.00 77.36 ? 388 ASN A O 1 +ATOM 2355 C CB . ASN A 1 326 ? -84.324 9.859 -54.299 1.00 78.66 ? 388 ASN A CB 1 +ATOM 2356 C CG . ASN A 1 326 ? -84.620 8.377 -54.049 1.00 77.97 ? 388 ASN A CG 1 +ATOM 2357 O OD1 . ASN A 1 326 ? -83.730 7.596 -53.711 1.00 74.54 ? 388 ASN A OD1 1 +ATOM 2358 N ND2 . ASN A 1 326 ? -85.883 7.994 -54.202 1.00 81.28 ? 388 ASN A ND2 1 +ATOM 2359 N N . ASN A 1 327 ? -83.061 9.396 -51.237 1.00 92.97 ? 389 ASN A N 1 +ATOM 2360 C CA . ASN A 1 327 ? -83.334 9.340 -49.804 1.00 98.22 ? 389 ASN A CA 1 +ATOM 2361 C C . ASN A 1 327 ? -82.507 10.337 -48.999 1.00 95.95 ? 389 ASN A C 1 +ATOM 2362 O O . ASN A 1 327 ? -82.755 10.486 -47.795 1.00 89.69 ? 389 ASN A O 1 +ATOM 2363 C CB . ASN A 1 327 ? -83.110 7.916 -49.266 1.00 93.38 ? 389 ASN A CB 1 +ATOM 2364 C CG . ASN A 1 327 ? -81.702 7.394 -49.523 1.00 84.88 ? 389 ASN A CG 1 +ATOM 2365 O OD1 . ASN A 1 327 ? -80.739 7.834 -48.898 1.00 88.16 ? 389 ASN A OD1 1 +ATOM 2366 N ND2 . ASN A 1 327 ? -81.585 6.428 -50.423 1.00 82.00 ? 389 ASN A ND2 1 +ATOM 2367 N N . SER A 1 328 ? -81.540 11.012 -49.626 1.00 92.20 ? 390 SER A N 1 +ATOM 2368 C CA . SER A 1 328 ? -80.709 12.042 -48.998 1.00 98.57 ? 390 SER A CA 1 +ATOM 2369 C C . SER A 1 328 ? -79.921 11.523 -47.794 1.00 86.62 ? 390 SER A C 1 +ATOM 2370 O O . SER A 1 328 ? -79.471 12.311 -46.957 1.00 77.45 ? 390 SER A O 1 +ATOM 2371 C CB . SER A 1 328 ? -81.552 13.258 -48.590 1.00 100.52 ? 390 SER A CB 1 +ATOM 2372 O OG . SER A 1 328 ? -82.152 13.882 -49.714 1.00 87.86 ? 390 SER A OG 1 +ATOM 2373 N N . GLN A 1 329 ? -79.746 10.208 -47.688 1.00 88.28 ? 391 GLN A N 1 +ATOM 2374 C CA . GLN A 1 329 ? -78.919 9.589 -46.660 1.00 79.34 ? 391 GLN A CA 1 +ATOM 2375 C C . GLN A 1 329 ? -77.708 8.865 -47.230 1.00 69.24 ? 391 GLN A C 1 +ATOM 2376 O O . GLN A 1 329 ? -76.652 8.846 -46.591 1.00 56.92 ? 391 GLN A O 1 +ATOM 2377 C CB . GLN A 1 329 ? -79.759 8.598 -45.829 1.00 74.49 ? 391 GLN A CB 1 +ATOM 2378 C CG . GLN A 1 329 ? -79.065 8.032 -44.598 1.00 69.32 ? 391 GLN A CG 1 +ATOM 2379 C CD . GLN A 1 329 ? -78.801 9.080 -43.537 1.00 69.02 ? 391 GLN A CD 1 +ATOM 2380 O OE1 . GLN A 1 329 ? -79.591 10.009 -43.351 1.00 71.68 ? 391 GLN A OE1 1 +ATOM 2381 N NE2 . GLN A 1 329 ? -77.678 8.940 -42.837 1.00 57.50 ? 391 GLN A NE2 1 +ATOM 2382 N N . ARG A 1 330 ? -77.839 8.273 -48.419 1.00 75.45 ? 392 ARG A N 1 +ATOM 2383 C CA . ARG A 1 330 ? -76.688 7.700 -49.106 1.00 75.05 ? 392 ARG A CA 1 +ATOM 2384 C C . ARG A 1 330 ? -75.753 8.795 -49.597 1.00 69.44 ? 392 ARG A C 1 +ATOM 2385 O O . ARG A 1 330 ? -74.525 8.646 -49.547 1.00 61.31 ? 392 ARG A O 1 +ATOM 2386 C CB . ARG A 1 330 ? -77.163 6.832 -50.275 1.00 82.89 ? 392 ARG A CB 1 +ATOM 2387 C CG . ARG A 1 330 ? -76.086 6.448 -51.298 1.00 79.02 ? 392 ARG A CG 1 +ATOM 2388 C CD . ARG A 1 330 ? -75.307 5.217 -50.857 1.00 72.56 ? 392 ARG A CD 1 +ATOM 2389 N NE . ARG A 1 330 ? -76.109 4.003 -50.975 1.00 70.71 ? 392 ARG A NE 1 +ATOM 2390 C CZ . ARG A 1 330 ? -76.257 3.316 -52.101 1.00 70.73 ? 392 ARG A CZ 1 +ATOM 2391 N NH1 . ARG A 1 330 ? -75.654 3.728 -53.206 1.00 69.20 ? 392 ARG A NH1 1 +ATOM 2392 N NH2 . ARG A 1 330 ? -77.006 2.221 -52.120 1.00 75.34 ? 392 ARG A NH2 1 +ATOM 2393 N N . LEU A 1 331 ? -76.320 9.910 -50.064 1.00 69.65 ? 393 LEU A N 1 +ATOM 2394 C CA . LEU A 1 331 ? -75.490 11.006 -50.552 1.00 71.32 ? 393 LEU A CA 1 +ATOM 2395 C C . LEU A 1 331 ? -74.600 11.560 -49.451 1.00 63.39 ? 393 LEU A C 1 +ATOM 2396 O O . LEU A 1 331 ? -73.439 11.903 -49.704 1.00 54.72 ? 393 LEU A O 1 +ATOM 2397 C CB . LEU A 1 331 ? -76.370 12.115 -51.138 1.00 71.42 ? 393 LEU A CB 1 +ATOM 2398 C CG . LEU A 1 331 ? -75.655 13.293 -51.809 1.00 58.07 ? 393 LEU A CG 1 +ATOM 2399 C CD1 . LEU A 1 331 ? -74.701 12.812 -52.892 1.00 59.68 ? 393 LEU A CD1 1 +ATOM 2400 C CD2 . LEU A 1 331 ? -76.670 14.261 -52.386 1.00 51.49 ? 393 LEU A CD2 1 +ATOM 2401 N N . LEU A 1 332 ? -75.102 11.604 -48.217 1.00 65.23 ? 394 LEU A N 1 +ATOM 2402 C CA . LEU A 1 332 ? -74.291 12.121 -47.125 1.00 57.31 ? 394 LEU A CA 1 +ATOM 2403 C C . LEU A 1 332 ? -73.083 11.238 -46.885 1.00 56.10 ? 394 LEU A C 1 +ATOM 2404 O O . LEU A 1 332 ? -71.980 11.740 -46.645 1.00 57.94 ? 394 LEU A O 1 +ATOM 2405 C CB . LEU A 1 332 ? -75.125 12.230 -45.854 1.00 59.61 ? 394 LEU A CB 1 +ATOM 2406 C CG . LEU A 1 332 ? -76.293 13.199 -45.945 1.00 65.12 ? 394 LEU A CG 1 +ATOM 2407 C CD1 . LEU A 1 332 ? -77.136 13.144 -44.683 1.00 66.76 ? 394 LEU A CD1 1 +ATOM 2408 C CD2 . LEU A 1 332 ? -75.743 14.594 -46.170 1.00 62.09 ? 394 LEU A CD2 1 +ATOM 2409 N N . ASN A 1 333 ? -73.262 9.921 -46.982 1.00 56.13 ? 395 ASN A N 1 +ATOM 2410 C CA . ASN A 1 333 ? -72.127 9.023 -46.814 1.00 60.41 ? 395 ASN A CA 1 +ATOM 2411 C C . ASN A 1 333 ? -71.093 9.215 -47.915 1.00 58.06 ? 395 ASN A C 1 +ATOM 2412 O O . ASN A 1 333 ? -69.891 9.055 -47.670 1.00 55.45 ? 395 ASN A O 1 +ATOM 2413 C CB . ASN A 1 333 ? -72.607 7.575 -46.766 1.00 62.09 ? 395 ASN A CB 1 +ATOM 2414 C CG . ASN A 1 333 ? -73.398 7.273 -45.518 1.00 64.65 ? 395 ASN A CG 1 +ATOM 2415 O OD1 . ASN A 1 333 ? -72.841 6.830 -44.509 1.00 62.51 ? 395 ASN A OD1 1 +ATOM 2416 N ND2 . ASN A 1 333 ? -74.707 7.518 -45.572 1.00 62.04 ? 395 ASN A ND2 1 +ATOM 2417 N N . VAL A 1 334 ? -71.531 9.578 -49.122 1.00 55.36 ? 396 VAL A N 1 +ATOM 2418 C CA . VAL A 1 334 ? -70.569 9.845 -50.185 1.00 54.50 ? 396 VAL A CA 1 +ATOM 2419 C C . VAL A 1 334 ? -69.811 11.130 -49.898 1.00 51.01 ? 396 VAL A C 1 +ATOM 2420 O O . VAL A 1 334 ? -68.640 11.269 -50.275 1.00 43.11 ? 396 VAL A O 1 +ATOM 2421 C CB . VAL A 1 334 ? -71.276 9.905 -51.547 1.00 55.76 ? 396 VAL A CB 1 +ATOM 2422 C CG1 . VAL A 1 334 ? -70.251 10.006 -52.666 1.00 47.34 ? 396 VAL A CG1 1 +ATOM 2423 C CG2 . VAL A 1 334 ? -72.181 8.698 -51.726 1.00 62.18 ? 396 VAL A CG2 1 +ATOM 2424 N N . ILE A 1 335 ? -70.464 12.090 -49.242 1.00 55.88 ? 397 ILE A N 1 +ATOM 2425 C CA . ILE A 1 335 ? -69.796 13.335 -48.874 1.00 51.14 ? 397 ILE A CA 1 +ATOM 2426 C C . ILE A 1 335 ? -68.655 13.059 -47.905 1.00 48.70 ? 397 ILE A C 1 +ATOM 2427 O O . ILE A 1 335 ? -67.556 13.611 -48.040 1.00 49.94 ? 397 ILE A O 1 +ATOM 2428 C CB . ILE A 1 335 ? -70.806 14.325 -48.272 1.00 50.00 ? 397 ILE A CB 1 +ATOM 2429 C CG1 . ILE A 1 335 ? -71.972 14.562 -49.239 1.00 47.59 ? 397 ILE A CG1 1 +ATOM 2430 C CG2 . ILE A 1 335 ? -70.100 15.617 -47.900 1.00 47.93 ? 397 ILE A CG2 1 +ATOM 2431 C CD1 . ILE A 1 335 ? -71.609 15.340 -50.473 1.00 50.46 ? 397 ILE A CD1 1 +ATOM 2432 N N . ASP A 1 336 ? -68.911 12.225 -46.893 1.00 48.42 ? 398 ASP A N 1 +ATOM 2433 C CA . ASP A 1 336 ? -67.850 11.855 -45.962 1.00 45.15 ? 398 ASP A CA 1 +ATOM 2434 C C . ASP A 1 336 ? -66.694 11.194 -46.694 1.00 46.30 ? 398 ASP A C 1 +ATOM 2435 O O . ASP A 1 336 ? -65.527 11.532 -46.461 1.00 40.11 ? 398 ASP A O 1 +ATOM 2436 C CB . ASP A 1 336 ? -68.392 10.920 -44.883 1.00 50.60 ? 398 ASP A CB 1 +ATOM 2437 C CG . ASP A 1 336 ? -69.348 11.611 -43.932 1.00 53.32 ? 398 ASP A CG 1 +ATOM 2438 O OD1 . ASP A 1 336 ? -69.933 12.650 -44.306 1.00 49.09 ? 398 ASP A OD1 1 +ATOM 2439 O OD2 . ASP A 1 336 ? -69.519 11.106 -42.804 1.00 61.25 ? 398 ASP A OD2 1 +ATOM 2440 N N . MET A 1 337 ? -67.003 10.262 -47.601 1.00 50.61 ? 399 MET A N 1 +ATOM 2441 C CA . MET A 1 337 ? -65.955 9.608 -48.378 1.00 58.09 ? 399 MET A CA 1 +ATOM 2442 C C . MET A 1 337 ? -65.169 10.627 -49.192 1.00 48.64 ? 399 MET A C 1 +ATOM 2443 O O . MET A 1 337 ? -63.943 10.522 -49.317 1.00 50.60 ? 399 MET A O 1 +ATOM 2444 C CB . MET A 1 337 ? -66.562 8.526 -49.280 1.00 61.93 ? 399 MET A CB 1 +ATOM 2445 C CG . MET A 1 337 ? -65.538 7.688 -50.064 1.00 64.95 ? 399 MET A CG 1 +ATOM 2446 S SD . MET A 1 337 ? -66.260 6.280 -50.941 1.00 68.46 ? 399 MET A SD 1 +ATOM 2447 C CE . MET A 1 337 ? -67.491 7.089 -51.963 1.00 62.77 ? 399 MET A CE 1 +ATOM 2448 N N . ALA A 1 338 ? -65.851 11.645 -49.719 1.00 40.73 ? 400 ALA A N 1 +ATOM 2449 C CA . ALA A 1 338 ? -65.136 12.686 -50.445 1.00 42.98 ? 400 ALA A CA 1 +ATOM 2450 C C . ALA A 1 338 ? -64.183 13.425 -49.523 1.00 42.60 ? 400 ALA A C 1 +ATOM 2451 O O . ALA A 1 338 ? -63.014 13.639 -49.864 1.00 40.22 ? 400 ALA A O 1 +ATOM 2452 C CB . ALA A 1 338 ? -66.128 13.662 -51.078 1.00 43.23 ? 400 ALA A CB 1 +ATOM 2453 N N . ILE A 1 339 ? -64.645 13.752 -48.317 1.00 42.57 ? 401 ILE A N 1 +ATOM 2454 C CA . ILE A 1 339 ? -63.796 14.451 -47.361 1.00 40.68 ? 401 ILE A CA 1 +ATOM 2455 C C . ILE A 1 339 ? -62.569 13.611 -47.054 1.00 44.14 ? 401 ILE A C 1 +ATOM 2456 O O . ILE A 1 339 ? -61.430 14.091 -47.111 1.00 42.59 ? 401 ILE A O 1 +ATOM 2457 C CB . ILE A 1 339 ? -64.597 14.771 -46.088 1.00 38.00 ? 401 ILE A CB 1 +ATOM 2458 C CG1 . ILE A 1 339 ? -65.764 15.701 -46.435 1.00 38.00 ? 401 ILE A CG1 1 +ATOM 2459 C CG2 . ILE A 1 339 ? -63.687 15.362 -45.024 1.00 38.00 ? 401 ILE A CG2 1 +ATOM 2460 C CD1 . ILE A 1 339 ? -66.682 16.018 -45.294 1.00 38.00 ? 401 ILE A CD1 1 +ATOM 2461 N N . PHE A 1 340 ? -62.788 12.322 -46.794 1.00 45.75 ? 402 PHE A N 1 +ATOM 2462 C CA . PHE A 1 340 ? -61.686 11.434 -46.453 1.00 45.97 ? 402 PHE A CA 1 +ATOM 2463 C C . PHE A 1 340 ? -60.704 11.301 -47.611 1.00 50.57 ? 402 PHE A C 1 +ATOM 2464 O O . PHE A 1 340 ? -59.488 11.236 -47.398 1.00 50.07 ? 402 PHE A O 1 +ATOM 2465 C CB . PHE A 1 340 ? -62.243 10.073 -46.034 1.00 40.64 ? 402 PHE A CB 1 +ATOM 2466 C CG . PHE A 1 340 ? -61.189 9.078 -45.681 1.00 44.73 ? 402 PHE A CG 1 +ATOM 2467 C CD1 . PHE A 1 340 ? -60.359 9.295 -44.597 1.00 49.67 ? 402 PHE A CD1 1 +ATOM 2468 C CD2 . PHE A 1 340 ? -61.030 7.923 -46.424 1.00 47.71 ? 402 PHE A CD2 1 +ATOM 2469 C CE1 . PHE A 1 340 ? -59.379 8.383 -44.263 1.00 51.07 ? 402 PHE A CE1 1 +ATOM 2470 C CE2 . PHE A 1 340 ? -60.052 7.005 -46.099 1.00 50.81 ? 402 PHE A CE2 1 +ATOM 2471 C CZ . PHE A 1 340 ? -59.225 7.234 -45.014 1.00 50.70 ? 402 PHE A CZ 1 +ATOM 2472 N N . ASP A 1 341 ? -61.204 11.296 -48.848 1.00 52.62 ? 403 ASP A N 1 +ATOM 2473 C CA . ASP A 1 341 ? -60.301 11.195 -49.989 1.00 51.49 ? 403 ASP A CA 1 +ATOM 2474 C C . ASP A 1 341 ? -59.555 12.499 -50.212 1.00 52.49 ? 403 ASP A C 1 +ATOM 2475 O O . ASP A 1 341 ? -58.367 12.487 -50.549 1.00 52.87 ? 403 ASP A O 1 +ATOM 2476 C CB . ASP A 1 341 ? -61.073 10.811 -51.245 1.00 51.38 ? 403 ASP A CB 1 +ATOM 2477 C CG . ASP A 1 341 ? -61.527 9.380 -51.227 1.00 58.69 ? 403 ASP A CG 1 +ATOM 2478 O OD1 . ASP A 1 341 ? -60.769 8.520 -50.729 1.00 54.86 ? 403 ASP A OD1 1 +ATOM 2479 O OD2 . ASP A 1 341 ? -62.657 9.126 -51.688 1.00 64.20 ? 403 ASP A OD2 1 +ATOM 2480 N N . PHE A 1 342 ? -60.230 13.634 -50.022 1.00 48.48 ? 404 PHE A N 1 +ATOM 2481 C CA . PHE A 1 342 ? -59.552 14.908 -50.224 1.00 52.04 ? 404 PHE A CA 1 +ATOM 2482 C C . PHE A 1 342 ? -58.452 15.106 -49.192 1.00 48.14 ? 404 PHE A C 1 +ATOM 2483 O O . PHE A 1 342 ? -57.401 15.680 -49.500 1.00 48.51 ? 404 PHE A O 1 +ATOM 2484 C CB . PHE A 1 342 ? -60.550 16.065 -50.194 1.00 48.20 ? 404 PHE A CB 1 +ATOM 2485 C CG . PHE A 1 342 ? -59.903 17.422 -50.285 1.00 50.16 ? 404 PHE A CG 1 +ATOM 2486 C CD1 . PHE A 1 342 ? -59.061 17.732 -51.341 1.00 54.82 ? 404 PHE A CD1 1 +ATOM 2487 C CD2 . PHE A 1 342 ? -60.141 18.387 -49.323 1.00 55.09 ? 404 PHE A CD2 1 +ATOM 2488 C CE1 . PHE A 1 342 ? -58.457 18.972 -51.429 1.00 54.26 ? 404 PHE A CE1 1 +ATOM 2489 C CE2 . PHE A 1 342 ? -59.545 19.631 -49.405 1.00 54.79 ? 404 PHE A CE2 1 +ATOM 2490 C CZ . PHE A 1 342 ? -58.701 19.925 -50.462 1.00 57.29 ? 404 PHE A CZ 1 +ATOM 2491 N N . LEU A 1 343 ? -58.668 14.632 -47.966 1.00 38.00 ? 405 LEU A N 1 +ATOM 2492 C CA . LEU A 1 343 ? -57.625 14.740 -46.956 1.00 39.06 ? 405 LEU A CA 1 +ATOM 2493 C C . LEU A 1 343 ? -56.370 13.980 -47.371 1.00 48.60 ? 405 LEU A C 1 +ATOM 2494 O O . LEU A 1 343 ? -55.250 14.462 -47.168 1.00 49.50 ? 405 LEU A O 1 +ATOM 2495 C CB . LEU A 1 343 ? -58.157 14.238 -45.620 1.00 38.03 ? 405 LEU A CB 1 +ATOM 2496 C CG . LEU A 1 343 ? -59.081 15.263 -44.976 1.00 41.12 ? 405 LEU A CG 1 +ATOM 2497 C CD1 . LEU A 1 343 ? -59.842 14.644 -43.841 1.00 47.39 ? 405 LEU A CD1 1 +ATOM 2498 C CD2 . LEU A 1 343 ? -58.224 16.407 -44.468 1.00 41.52 ? 405 LEU A CD2 1 +ATOM 2499 N N . ILE A 1 344 ? -56.534 12.806 -47.987 1.00 51.02 ? 406 ILE A N 1 +ATOM 2500 C CA . ILE A 1 344 ? -55.390 12.000 -48.411 1.00 45.81 ? 406 ILE A CA 1 +ATOM 2501 C C . ILE A 1 344 ? -55.026 12.198 -49.874 1.00 46.16 ? 406 ILE A C 1 +ATOM 2502 O O . ILE A 1 344 ? -53.973 11.698 -50.303 1.00 47.33 ? 406 ILE A O 1 +ATOM 2503 C CB . ILE A 1 344 ? -55.634 10.503 -48.149 1.00 41.23 ? 406 ILE A CB 1 +ATOM 2504 C CG1 . ILE A 1 344 ? -56.814 10.040 -48.991 1.00 49.15 ? 406 ILE A CG1 1 +ATOM 2505 C CG2 . ILE A 1 344 ? -55.861 10.249 -46.673 1.00 38.00 ? 406 ILE A CG2 1 +ATOM 2506 C CD1 . ILE A 1 344 ? -57.186 8.614 -48.756 1.00 63.49 ? 406 ILE A CD1 1 +ATOM 2507 N N . GLY A 1 345 ? -55.858 12.884 -50.653 1.00 49.63 ? 407 GLY A N 1 +ATOM 2508 C CA . GLY A 1 345 ? -55.593 13.078 -52.072 1.00 51.66 ? 407 GLY A CA 1 +ATOM 2509 C C . GLY A 1 345 ? -55.788 11.831 -52.907 1.00 49.93 ? 407 GLY A C 1 +ATOM 2510 O O . GLY A 1 345 ? -54.985 11.554 -53.810 1.00 43.58 ? 407 GLY A O 1 +ATOM 2511 N N . ASN A 1 346 ? -56.865 11.094 -52.657 1.00 53.85 ? 408 ASN A N 1 +ATOM 2512 C CA . ASN A 1 346 ? -57.142 9.837 -53.347 1.00 57.16 ? 408 ASN A CA 1 +ATOM 2513 C C . ASN A 1 346 ? -58.100 10.178 -54.482 1.00 55.90 ? 408 ASN A C 1 +ATOM 2514 O O . ASN A 1 346 ? -59.318 10.218 -54.306 1.00 55.74 ? 408 ASN A O 1 +ATOM 2515 C CB . ASN A 1 346 ? -57.735 8.803 -52.392 1.00 56.99 ? 408 ASN A CB 1 +ATOM 2516 C CG . ASN A 1 346 ? -57.751 7.389 -52.970 1.00 54.34 ? 408 ASN A CG 1 +ATOM 2517 O OD1 . ASN A 1 346 ? -56.788 6.950 -53.617 1.00 46.36 ? 408 ASN A OD1 1 +ATOM 2518 N ND2 . ASN A 1 346 ? -58.863 6.679 -52.761 1.00 47.37 ? 408 ASN A ND2 1 +ATOM 2519 N N . MET A 1 347 ? -57.535 10.463 -55.653 1.00 49.35 ? 409 MET A N 1 +ATOM 2520 C CA . MET A 1 347 ? -58.377 10.728 -56.813 1.00 52.46 ? 409 MET A CA 1 +ATOM 2521 C C . MET A 1 347 ? -59.030 9.450 -57.323 1.00 54.97 ? 409 MET A C 1 +ATOM 2522 O O . MET A 1 347 ? -60.097 9.501 -57.945 1.00 57.71 ? 409 MET A O 1 +ATOM 2523 C CB . MET A 1 347 ? -57.547 11.390 -57.909 1.00 53.27 ? 409 MET A CB 1 +ATOM 2524 C CG . MET A 1 347 ? -56.578 12.425 -57.367 1.00 55.07 ? 409 MET A CG 1 +ATOM 2525 S SD . MET A 1 347 ? -55.739 13.369 -58.653 1.00 52.78 ? 409 MET A SD 1 +ATOM 2526 C CE . MET A 1 347 ? -54.443 14.179 -57.703 1.00 46.60 ? 409 MET A CE 1 +ATOM 2527 N N . ASP A 1 348 ? -58.411 8.303 -57.050 1.00 57.40 ? 410 ASP A N 1 +ATOM 2528 C CA . ASP A 1 348 ? -58.831 7.011 -57.594 1.00 53.57 ? 410 ASP A CA 1 +ATOM 2529 C C . ASP A 1 348 ? -59.840 6.337 -56.659 1.00 50.64 ? 410 ASP A C 1 +ATOM 2530 O O . ASP A 1 348 ? -59.547 5.357 -55.973 1.00 58.48 ? 410 ASP A O 1 +ATOM 2531 C CB . ASP A 1 348 ? -57.603 6.138 -57.822 1.00 52.37 ? 410 ASP A CB 1 +ATOM 2532 C CG . ASP A 1 348 ? -57.919 4.857 -58.556 1.00 62.39 ? 410 ASP A CG 1 +ATOM 2533 O OD1 . ASP A 1 348 ? -59.103 4.629 -58.885 1.00 67.83 ? 410 ASP A OD1 1 +ATOM 2534 O OD2 . ASP A 1 348 ? -56.975 4.073 -58.799 1.00 57.73 ? 410 ASP A OD2 1 +ATOM 2535 N N . ARG A 1 349 ? -61.058 6.867 -56.656 1.00 43.42 ? 411 ARG A N 1 +ATOM 2536 C CA . ARG A 1 349 ? -62.172 6.253 -55.936 1.00 46.95 ? 411 ARG A CA 1 +ATOM 2537 C C . ARG A 1 349 ? -63.320 6.019 -56.919 1.00 49.27 ? 411 ARG A C 1 +ATOM 2538 O O . ARG A 1 349 ? -64.387 6.637 -56.825 1.00 38.00 ? 411 ARG A O 1 +ATOM 2539 C CB . ARG A 1 349 ? -62.609 7.116 -54.739 1.00 49.83 ? 411 ARG A CB 1 +ATOM 2540 C CG . ARG A 1 349 ? -63.634 6.423 -53.836 1.00 57.10 ? 411 ARG A CG 1 +ATOM 2541 C CD . ARG A 1 349 ? -63.079 6.166 -52.446 1.00 53.53 ? 411 ARG A CD 1 +ATOM 2542 N NE . ARG A 1 349 ? -62.091 5.096 -52.444 1.00 59.71 ? 411 ARG A NE 1 +ATOM 2543 C CZ . ARG A 1 349 ? -61.317 4.800 -51.406 1.00 60.42 ? 411 ARG A CZ 1 +ATOM 2544 N NH1 . ARG A 1 349 ? -61.419 5.499 -50.283 1.00 56.38 ? 411 ARG A NH1 1 +ATOM 2545 N NH2 . ARG A 1 349 ? -60.442 3.805 -51.490 1.00 59.24 ? 411 ARG A NH2 1 +ATOM 2546 N N . HIS A 1 350 ? -63.102 5.084 -57.850 1.00 57.09 ? 412 HIS A N 1 +ATOM 2547 C CA . HIS A 1 350 ? -64.112 4.777 -58.860 1.00 62.21 ? 412 HIS A CA 1 +ATOM 2548 C C . HIS A 1 350 ? -65.296 4.009 -58.281 1.00 58.93 ? 412 HIS A C 1 +ATOM 2549 O O . HIS A 1 350 ? -66.430 4.174 -58.748 1.00 53.00 ? 412 HIS A O 1 +ATOM 2550 C CB . HIS A 1 350 ? -63.481 3.990 -60.018 1.00 64.84 ? 412 HIS A CB 1 +ATOM 2551 C CG . HIS A 1 350 ? -62.461 2.972 -59.597 1.00 64.93 ? 412 HIS A CG 1 +ATOM 2552 N ND1 . HIS A 1 350 ? -62.454 2.383 -58.350 1.00 62.56 ? 412 HIS A ND1 1 +ATOM 2553 C CD2 . HIS A 1 350 ? -61.413 2.437 -60.270 1.00 66.71 ? 412 HIS A CD2 1 +ATOM 2554 C CE1 . HIS A 1 350 ? -61.442 1.536 -58.271 1.00 69.94 ? 412 HIS A CE1 1 +ATOM 2555 N NE2 . HIS A 1 350 ? -60.796 1.549 -59.423 1.00 66.39 ? 412 HIS A NE2 1 +ATOM 2556 N N . HIS A 1 351 ? -65.063 3.166 -57.280 1.00 59.28 ? 413 HIS A N 1 +ATOM 2557 C CA . HIS A 1 351 ? -66.124 2.357 -56.706 1.00 54.73 ? 413 HIS A CA 1 +ATOM 2558 C C . HIS A 1 351 ? -65.990 2.331 -55.193 1.00 47.76 ? 413 HIS A C 1 +ATOM 2559 O O . HIS A 1 351 ? -64.880 2.274 -54.655 1.00 39.43 ? 413 HIS A O 1 +ATOM 2560 C CB . HIS A 1 351 ? -66.090 0.934 -57.260 1.00 60.35 ? 413 HIS A CB 1 +ATOM 2561 C CG . HIS A 1 351 ? -66.375 0.856 -58.726 1.00 58.72 ? 413 HIS A CG 1 +ATOM 2562 N ND1 . HIS A 1 351 ? -65.468 1.267 -59.678 1.00 52.99 ? 413 HIS A ND1 1 +ATOM 2563 C CD2 . HIS A 1 351 ? -67.458 0.409 -59.404 1.00 62.45 ? 413 HIS A CD2 1 +ATOM 2564 C CE1 . HIS A 1 351 ? -65.983 1.082 -60.880 1.00 63.70 ? 413 HIS A CE1 1 +ATOM 2565 N NE2 . HIS A 1 351 ? -67.190 0.563 -60.742 1.00 68.79 ? 413 HIS A NE2 1 +ATOM 2566 N N . TYR A 1 352 ? -67.128 2.370 -54.516 1.00 45.89 ? 414 TYR A N 1 +ATOM 2567 C CA . TYR A 1 352 ? -67.193 2.207 -53.075 1.00 46.07 ? 414 TYR A CA 1 +ATOM 2568 C C . TYR A 1 352 ? -68.048 0.991 -52.753 1.00 52.84 ? 414 TYR A C 1 +ATOM 2569 O O . TYR A 1 352 ? -69.128 0.816 -53.325 1.00 55.61 ? 414 TYR A O 1 +ATOM 2570 C CB . TYR A 1 352 ? -67.766 3.458 -52.415 1.00 47.13 ? 414 TYR A CB 1 +ATOM 2571 C CG . TYR A 1 352 ? -69.184 3.794 -52.821 1.00 42.18 ? 414 TYR A CG 1 +ATOM 2572 C CD1 . TYR A 1 352 ? -69.446 4.596 -53.922 1.00 47.22 ? 414 TYR A CD1 1 +ATOM 2573 C CD2 . TYR A 1 352 ? -70.260 3.315 -52.095 1.00 47.87 ? 414 TYR A CD2 1 +ATOM 2574 C CE1 . TYR A 1 352 ? -70.745 4.905 -54.287 1.00 50.97 ? 414 TYR A CE1 1 +ATOM 2575 C CE2 . TYR A 1 352 ? -71.554 3.614 -52.452 1.00 53.48 ? 414 TYR A CE2 1 +ATOM 2576 C CZ . TYR A 1 352 ? -71.794 4.409 -53.545 1.00 52.93 ? 414 TYR A CZ 1 +ATOM 2577 O OH . TYR A 1 352 ? -73.095 4.702 -53.885 1.00 54.99 ? 414 TYR A OH 1 +ATOM 2578 N N . GLU A 1 353 ? -67.578 0.159 -51.829 1.00 46.32 ? 415 GLU A N 1 +ATOM 2579 C CA . GLU A 1 353 ? -68.267 -1.079 -51.497 1.00 46.56 ? 415 GLU A CA 1 +ATOM 2580 C C . GLU A 1 353 ? -69.153 -0.896 -50.274 1.00 44.48 ? 415 GLU A C 1 +ATOM 2581 O O . GLU A 1 353 ? -68.906 -0.034 -49.427 1.00 46.30 ? 415 GLU A O 1 +ATOM 2582 C CB . GLU A 1 353 ? -67.273 -2.213 -51.258 1.00 47.67 ? 415 GLU A CB 1 +ATOM 2583 C CG . GLU A 1 353 ? -66.537 -2.642 -52.511 1.00 53.18 ? 415 GLU A CG 1 +ATOM 2584 C CD . GLU A 1 353 ? -65.771 -3.933 -52.315 1.00 61.84 ? 415 GLU A CD 1 +ATOM 2585 O OE1 . GLU A 1 353 ? -65.996 -4.608 -51.287 1.00 59.19 ? 415 GLU A OE1 1 +ATOM 2586 O OE2 . GLU A 1 353 ? -64.935 -4.266 -53.182 1.00 64.63 ? 415 GLU A OE2 1 +ATOM 2587 N N . MET A 1 354 ? -70.201 -1.715 -50.201 1.00 47.76 ? 416 MET A N 1 +ATOM 2588 C CA . MET A 1 354 ? -71.171 -1.667 -49.117 1.00 49.40 ? 416 MET A CA 1 +ATOM 2589 C C . MET A 1 354 ? -71.517 -3.081 -48.678 1.00 53.17 ? 416 MET A C 1 +ATOM 2590 O O . MET A 1 354 ? -71.401 -4.030 -49.456 1.00 60.85 ? 416 MET A O 1 +ATOM 2591 C CB . MET A 1 354 ? -72.458 -0.958 -49.542 1.00 39.99 ? 416 MET A CB 1 +ATOM 2592 C CG . MET A 1 354 ? -72.253 0.412 -50.127 1.00 39.05 ? 416 MET A CG 1 +ATOM 2593 S SD . MET A 1 354 ? -73.837 1.169 -50.494 1.00 54.73 ? 416 MET A SD 1 +ATOM 2594 C CE . MET A 1 354 ? -74.700 0.904 -48.947 1.00 56.78 ? 416 MET A CE 1 +ATOM 2595 N N . PHE A 1 355 ? -71.942 -3.218 -47.422 1.00 51.38 ? 417 PHE A N 1 +ATOM 2596 C CA . PHE A 1 355 ? -72.475 -4.481 -46.922 1.00 53.31 ? 417 PHE A CA 1 +ATOM 2597 C C . PHE A 1 355 ? -73.971 -4.529 -47.219 1.00 59.23 ? 417 PHE A C 1 +ATOM 2598 O O . PHE A 1 355 ? -74.724 -3.644 -46.791 1.00 57.25 ? 417 PHE A O 1 +ATOM 2599 C CB . PHE A 1 355 ? -72.209 -4.646 -45.428 1.00 48.31 ? 417 PHE A CB 1 +ATOM 2600 C CG . PHE A 1 355 ? -70.775 -4.916 -45.099 1.00 45.82 ? 417 PHE A CG 1 +ATOM 2601 C CD1 . PHE A 1 355 ? -70.177 -6.102 -45.480 1.00 51.35 ? 417 PHE A CD1 1 +ATOM 2602 C CD2 . PHE A 1 355 ? -70.024 -3.988 -44.398 1.00 51.27 ? 417 PHE A CD2 1 +ATOM 2603 C CE1 . PHE A 1 355 ? -68.848 -6.357 -45.176 1.00 59.50 ? 417 PHE A CE1 1 +ATOM 2604 C CE2 . PHE A 1 355 ? -68.697 -4.236 -44.085 1.00 50.64 ? 417 PHE A CE2 1 +ATOM 2605 C CZ . PHE A 1 355 ? -68.107 -5.422 -44.477 1.00 53.87 ? 417 PHE A CZ 1 +ATOM 2606 N N . THR A 1 356 ? -74.398 -5.562 -47.952 1.00 60.23 ? 418 THR A N 1 +ATOM 2607 C CA . THR A 1 356 ? -75.780 -5.638 -48.414 1.00 63.54 ? 418 THR A CA 1 +ATOM 2608 C C . THR A 1 356 ? -76.783 -5.775 -47.270 1.00 56.25 ? 418 THR A C 1 +ATOM 2609 O O . THR A 1 356 ? -77.951 -5.412 -47.445 1.00 55.76 ? 418 THR A O 1 +ATOM 2610 C CB . THR A 1 356 ? -75.939 -6.793 -49.415 1.00 54.51 ? 418 THR A CB 1 +ATOM 2611 O OG1 . THR A 1 356 ? -77.328 -6.994 -49.700 1.00 50.27 ? 418 THR A OG1 1 +ATOM 2612 C CG2 . THR A 1 356 ? -75.361 -8.075 -48.870 1.00 51.14 ? 418 THR A CG2 1 +ATOM 2613 N N . LYS A 1 357 ? -76.355 -6.272 -46.107 1.00 54.77 ? 419 LYS A N 1 +ATOM 2614 C CA . LYS A 1 357 ? -77.274 -6.450 -44.985 1.00 57.55 ? 419 LYS A CA 1 +ATOM 2615 C C . LYS A 1 357 ? -77.784 -5.121 -44.444 1.00 64.94 ? 419 LYS A C 1 +ATOM 2616 O O . LYS A 1 357 ? -78.909 -5.049 -43.931 1.00 65.16 ? 419 LYS A O 1 +ATOM 2617 C CB . LYS A 1 357 ? -76.583 -7.234 -43.869 1.00 54.21 ? 419 LYS A CB 1 +ATOM 2618 C CG . LYS A 1 357 ? -77.426 -7.415 -42.623 1.00 57.38 ? 419 LYS A CG 1 +ATOM 2619 C CD . LYS A 1 357 ? -76.785 -8.385 -41.658 1.00 55.58 ? 419 LYS A CD 1 +ATOM 2620 C CE . LYS A 1 357 ? -77.603 -8.512 -40.387 1.00 60.71 ? 419 LYS A CE 1 +ATOM 2621 N NZ . LYS A 1 357 ? -77.035 -9.536 -39.479 1.00 65.03 ? 419 LYS A NZ 1 +ATOM 2622 N N . PHE A 1 358 ? -76.987 -4.063 -44.563 1.00 65.11 ? 420 PHE A N 1 +ATOM 2623 C CA . PHE A 1 358 ? -77.298 -2.782 -43.946 1.00 68.22 ? 420 PHE A CA 1 +ATOM 2624 C C . PHE A 1 358 ? -78.156 -1.874 -44.819 1.00 70.04 ? 420 PHE A C 1 +ATOM 2625 O O . PHE A 1 358 ? -78.619 -0.835 -44.333 1.00 73.25 ? 420 PHE A O 1 +ATOM 2626 C CB . PHE A 1 358 ? -75.998 -2.076 -43.560 1.00 70.29 ? 420 PHE A CB 1 +ATOM 2627 C CG . PHE A 1 358 ? -75.203 -2.817 -42.524 1.00 63.58 ? 420 PHE A CG 1 +ATOM 2628 C CD1 . PHE A 1 358 ? -75.844 -3.559 -41.543 1.00 54.36 ? 420 PHE A CD1 1 +ATOM 2629 C CD2 . PHE A 1 358 ? -73.818 -2.789 -42.539 1.00 63.19 ? 420 PHE A CD2 1 +ATOM 2630 C CE1 . PHE A 1 358 ? -75.120 -4.242 -40.591 1.00 59.85 ? 420 PHE A CE1 1 +ATOM 2631 C CE2 . PHE A 1 358 ? -73.087 -3.473 -41.588 1.00 57.65 ? 420 PHE A CE2 1 +ATOM 2632 C CZ . PHE A 1 358 ? -73.739 -4.200 -40.612 1.00 60.71 ? 420 PHE A CZ 1 +ATOM 2633 N N . GLY A 1 359 ? -78.364 -2.218 -46.085 1.00 63.56 ? 421 GLY A N 1 +ATOM 2634 C CA . GLY A 1 359 ? -79.300 -1.482 -46.904 1.00 62.06 ? 421 GLY A CA 1 +ATOM 2635 C C . GLY A 1 359 ? -78.701 -0.218 -47.495 1.00 72.48 ? 421 GLY A C 1 +ATOM 2636 O O . GLY A 1 359 ? -77.499 0.051 -47.406 1.00 76.89 ? 421 GLY A O 1 +ATOM 2637 N N . ASP A 1 360 ? -79.585 0.577 -48.109 1.00 72.59 ? 422 ASP A N 1 +ATOM 2638 C CA . ASP A 1 360 ? -79.155 1.791 -48.800 1.00 72.53 ? 422 ASP A CA 1 +ATOM 2639 C C . ASP A 1 360 ? -78.537 2.806 -47.849 1.00 69.20 ? 422 ASP A C 1 +ATOM 2640 O O . ASP A 1 360 ? -77.668 3.587 -48.256 1.00 70.69 ? 422 ASP A O 1 +ATOM 2641 C CB . ASP A 1 360 ? -80.332 2.406 -49.556 1.00 70.99 ? 422 ASP A CB 1 +ATOM 2642 C CG . ASP A 1 360 ? -81.098 1.376 -50.372 1.00 83.81 ? 422 ASP A CG 1 +ATOM 2643 O OD1 . ASP A 1 360 ? -81.844 0.569 -49.777 1.00 79.04 ? 422 ASP A OD1 1 +ATOM 2644 O OD2 . ASP A 1 360 ? -80.936 1.361 -51.612 1.00 87.23 ? 422 ASP A OD2 1 +ATOM 2645 N N . ASP A 1 361 ? -78.948 2.802 -46.584 1.00 67.82 ? 423 ASP A N 1 +ATOM 2646 C CA . ASP A 1 361 ? -78.406 3.724 -45.596 1.00 67.85 ? 423 ASP A CA 1 +ATOM 2647 C C . ASP A 1 361 ? -77.113 3.222 -44.972 1.00 66.09 ? 423 ASP A C 1 +ATOM 2648 O O . ASP A 1 361 ? -76.544 3.908 -44.118 1.00 67.97 ? 423 ASP A O 1 +ATOM 2649 C CB . ASP A 1 361 ? -79.438 3.984 -44.493 1.00 61.77 ? 423 ASP A CB 1 +ATOM 2650 C CG . ASP A 1 361 ? -80.659 4.719 -45.001 1.00 65.76 ? 423 ASP A CG 1 +ATOM 2651 O OD1 . ASP A 1 361 ? -80.554 5.400 -46.042 1.00 75.92 ? 423 ASP A OD1 1 +ATOM 2652 O OD2 . ASP A 1 361 ? -81.726 4.612 -44.361 1.00 63.94 ? 423 ASP A OD2 1 +ATOM 2653 N N . GLY A 1 362 ? -76.629 2.058 -45.392 1.00 69.17 ? 424 GLY A N 1 +ATOM 2654 C CA . GLY A 1 362 ? -75.415 1.518 -44.820 1.00 67.76 ? 424 GLY A CA 1 +ATOM 2655 C C . GLY A 1 362 ? -74.204 2.381 -45.108 1.00 59.84 ? 424 GLY A C 1 +ATOM 2656 O O . GLY A 1 362 ? -74.158 3.161 -46.063 1.00 52.26 ? 424 GLY A O 1 +ATOM 2657 N N . PHE A 1 363 ? -73.214 2.243 -44.230 1.00 55.53 ? 425 PHE A N 1 +ATOM 2658 C CA . PHE A 1 363 ? -71.974 2.980 -44.378 1.00 52.29 ? 425 PHE A CA 1 +ATOM 2659 C C . PHE A 1 363 ? -71.158 2.411 -45.529 1.00 51.97 ? 425 PHE A C 1 +ATOM 2660 O O . PHE A 1 363 ? -71.357 1.276 -45.971 1.00 49.95 ? 425 PHE A O 1 +ATOM 2661 C CB . PHE A 1 363 ? -71.157 2.932 -43.087 1.00 54.64 ? 425 PHE A CB 1 +ATOM 2662 C CG . PHE A 1 363 ? -70.662 1.551 -42.713 1.00 54.49 ? 425 PHE A CG 1 +ATOM 2663 C CD1 . PHE A 1 363 ? -71.507 0.639 -42.094 1.00 50.77 ? 425 PHE A CD1 1 +ATOM 2664 C CD2 . PHE A 1 363 ? -69.337 1.188 -42.928 1.00 46.60 ? 425 PHE A CD2 1 +ATOM 2665 C CE1 . PHE A 1 363 ? -71.050 -0.617 -41.730 1.00 48.48 ? 425 PHE A CE1 1 +ATOM 2666 C CE2 . PHE A 1 363 ? -68.876 -0.065 -42.560 1.00 42.62 ? 425 PHE A CE2 1 +ATOM 2667 C CZ . PHE A 1 363 ? -69.733 -0.967 -41.962 1.00 46.85 ? 425 PHE A CZ 1 +ATOM 2668 N N . LEU A 1 364 ? -70.203 3.204 -45.992 1.00 54.11 ? 426 LEU A N 1 +ATOM 2669 C CA . LEU A 1 364 ? -69.364 2.834 -47.118 1.00 47.10 ? 426 LEU A CA 1 +ATOM 2670 C C . LEU A 1 364 ? -68.017 2.341 -46.618 1.00 45.11 ? 426 LEU A C 1 +ATOM 2671 O O . LEU A 1 364 ? -67.495 2.840 -45.619 1.00 52.68 ? 426 LEU A O 1 +ATOM 2672 C CB . LEU A 1 364 ? -69.161 4.018 -48.057 1.00 49.27 ? 426 LEU A CB 1 +ATOM 2673 C CG . LEU A 1 364 ? -70.408 4.834 -48.388 1.00 52.95 ? 426 LEU A CG 1 +ATOM 2674 C CD1 . LEU A 1 364 ? -70.066 5.814 -49.498 1.00 56.54 ? 426 LEU A CD1 1 +ATOM 2675 C CD2 . LEU A 1 364 ? -71.598 3.955 -48.762 1.00 47.16 ? 426 LEU A CD2 1 +ATOM 2676 N N . ILE A 1 365 ? -67.472 1.345 -47.301 1.00 38.00 ? 427 ILE A N 1 +ATOM 2677 C CA . ILE A 1 365 ? -66.166 0.791 -46.974 1.00 44.19 ? 427 ILE A CA 1 +ATOM 2678 C C . ILE A 1 365 ? -65.120 1.465 -47.850 1.00 42.58 ? 427 ILE A C 1 +ATOM 2679 O O . ILE A 1 365 ? -65.243 1.476 -49.080 1.00 46.83 ? 427 ILE A O 1 +ATOM 2680 C CB . ILE A 1 365 ? -66.153 -0.735 -47.159 1.00 45.87 ? 427 ILE A CB 1 +ATOM 2681 C CG1 . ILE A 1 365 ? -67.516 -1.316 -46.790 1.00 40.30 ? 427 ILE A CG1 1 +ATOM 2682 C CG2 . ILE A 1 365 ? -65.063 -1.389 -46.330 1.00 42.85 ? 427 ILE A CG2 1 +ATOM 2683 C CD1 . ILE A 1 365 ? -67.596 -2.791 -47.020 1.00 46.70 ? 427 ILE A CD1 1 +ATOM 2684 N N . HIS A 1 366 ? -64.080 2.009 -47.224 1.00 38.00 ? 428 HIS A N 1 +ATOM 2685 C CA . HIS A 1 366 ? -63.017 2.693 -47.951 1.00 43.42 ? 428 HIS A CA 1 +ATOM 2686 C C . HIS A 1 366 ? -61.836 1.726 -48.029 1.00 47.76 ? 428 HIS A C 1 +ATOM 2687 O O . HIS A 1 366 ? -60.898 1.776 -47.233 1.00 48.26 ? 428 HIS A O 1 +ATOM 2688 C CB . HIS A 1 366 ? -62.646 4.010 -47.265 1.00 53.49 ? 428 HIS A CB 1 +ATOM 2689 C CG . HIS A 1 366 ? -63.820 4.883 -46.917 1.00 56.83 ? 428 HIS A CG 1 +ATOM 2690 N ND1 . HIS A 1 366 ? -63.725 5.935 -46.028 1.00 48.23 ? 428 HIS A ND1 1 +ATOM 2691 C CD2 . HIS A 1 366 ? -65.111 4.860 -47.330 1.00 53.34 ? 428 HIS A CD2 1 +ATOM 2692 C CE1 . HIS A 1 366 ? -64.904 6.521 -45.911 1.00 48.78 ? 428 HIS A CE1 1 +ATOM 2693 N NE2 . HIS A 1 366 ? -65.763 5.888 -46.690 1.00 48.26 ? 428 HIS A NE2 1 +ATOM 2694 N N . LEU A 1 367 ? -61.892 0.832 -49.021 1.00 51.14 ? 429 LEU A N 1 +ATOM 2695 C CA . LEU A 1 367 ? -60.998 -0.330 -49.045 1.00 54.76 ? 429 LEU A CA 1 +ATOM 2696 C C . LEU A 1 367 ? -59.578 0.015 -49.478 1.00 59.07 ? 429 LEU A C 1 +ATOM 2697 O O . LEU A 1 367 ? -58.633 -0.095 -48.691 1.00 63.74 ? 429 LEU A O 1 +ATOM 2698 C CB . LEU A 1 367 ? -61.566 -1.423 -49.955 1.00 52.99 ? 429 LEU A CB 1 +ATOM 2699 C CG . LEU A 1 367 ? -62.573 -2.377 -49.323 1.00 55.16 ? 429 LEU A CG 1 +ATOM 2700 C CD1 . LEU A 1 367 ? -62.944 -3.481 -50.295 1.00 62.22 ? 429 LEU A CD1 1 +ATOM 2701 C CD2 . LEU A 1 367 ? -61.989 -2.972 -48.056 1.00 56.71 ? 429 LEU A CD2 1 +ATOM 2702 N N . ASP A 1 368 ? -59.403 0.401 -50.733 1.00 56.28 ? 430 ASP A N 1 +ATOM 2703 C CA . ASP A 1 368 ? -58.069 0.560 -51.307 1.00 66.50 ? 430 ASP A CA 1 +ATOM 2704 C C . ASP A 1 368 ? -57.745 2.047 -51.350 1.00 55.01 ? 430 ASP A C 1 +ATOM 2705 O O . ASP A 1 368 ? -58.238 2.778 -52.211 1.00 55.25 ? 430 ASP A O 1 +ATOM 2706 C CB . ASP A 1 368 ? -57.977 -0.102 -52.681 1.00 81.37 ? 430 ASP A CB 1 +ATOM 2707 C CG . ASP A 1 368 ? -57.905 -1.642 -52.599 1.00 80.02 ? 430 ASP A CG 1 +ATOM 2708 O OD1 . ASP A 1 368 ? -56.937 -2.173 -51.999 1.00 69.59 ? 430 ASP A OD1 1 +ATOM 2709 O OD2 . ASP A 1 368 ? -58.809 -2.321 -53.144 1.00 84.87 ? 430 ASP A OD2 1 +ATOM 2710 N N . ASN A 1 369 ? -56.937 2.495 -50.388 1.00 56.37 ? 431 ASN A N 1 +ATOM 2711 C CA . ASN A 1 369 ? -56.524 3.887 -50.276 1.00 51.70 ? 431 ASN A CA 1 +ATOM 2712 C C . ASN A 1 369 ? -55.053 4.089 -50.602 1.00 41.66 ? 431 ASN A C 1 +ATOM 2713 O O . ASN A 1 369 ? -54.515 5.165 -50.331 1.00 41.41 ? 431 ASN A O 1 +ATOM 2714 C CB . ASN A 1 369 ? -56.804 4.398 -48.863 1.00 50.17 ? 431 ASN A CB 1 +ATOM 2715 C CG . ASN A 1 369 ? -58.087 3.833 -48.289 1.00 57.65 ? 431 ASN A CG 1 +ATOM 2716 O OD1 . ASN A 1 369 ? -59.186 4.167 -48.738 1.00 54.56 ? 431 ASN A OD1 1 +ATOM 2717 N ND2 . ASN A 1 369 ? -57.953 2.966 -47.289 1.00 56.20 ? 431 ASN A ND2 1 +ATOM 2718 N N . ALA A 1 370 ? -54.399 3.088 -51.193 1.00 44.88 ? 432 ALA A N 1 +ATOM 2719 C CA . ALA A 1 370 ? -52.951 3.086 -51.372 1.00 48.54 ? 432 ALA A CA 1 +ATOM 2720 C C . ALA A 1 370 ? -52.440 4.169 -52.315 1.00 50.61 ? 432 ALA A C 1 +ATOM 2721 O O . ALA A 1 370 ? -51.223 4.238 -52.524 1.00 45.95 ? 432 ALA A O 1 +ATOM 2722 C CB . ALA A 1 370 ? -52.481 1.724 -51.871 1.00 54.97 ? 432 ALA A CB 1 +ATOM 2723 N N . ARG A 1 371 ? -53.320 4.967 -52.928 1.00 57.43 ? 433 ARG A N 1 +ATOM 2724 C CA . ARG A 1 371 ? -52.894 5.986 -53.885 1.00 60.99 ? 433 ARG A CA 1 +ATOM 2725 C C . ARG A 1 371 ? -52.774 7.376 -53.282 1.00 56.20 ? 433 ARG A C 1 +ATOM 2726 O O . ARG A 1 371 ? -51.950 8.172 -53.749 1.00 50.96 ? 433 ARG A O 1 +ATOM 2727 C CB . ARG A 1 371 ? -53.854 6.045 -55.080 1.00 56.10 ? 433 ARG A CB 1 +ATOM 2728 C CG . ARG A 1 371 ? -53.842 4.785 -55.929 1.00 55.84 ? 433 ARG A CG 1 +ATOM 2729 C CD . ARG A 1 371 ? -53.864 5.097 -57.420 1.00 51.87 ? 433 ARG A CD 1 +ATOM 2730 N NE . ARG A 1 371 ? -54.051 3.895 -58.234 1.00 56.02 ? 433 ARG A NE 1 +ATOM 2731 C CZ . ARG A 1 371 ? -53.421 3.658 -59.383 1.00 54.90 ? 433 ARG A CZ 1 +ATOM 2732 N NH1 . ARG A 1 371 ? -52.544 4.530 -59.858 1.00 50.61 ? 433 ARG A NH1 1 +ATOM 2733 N NH2 . ARG A 1 371 ? -53.653 2.538 -60.056 1.00 59.27 ? 433 ARG A NH2 1 +ATOM 2734 N N . GLY A 1 372 ? -53.539 7.674 -52.238 1.00 51.72 ? 434 GLY A N 1 +ATOM 2735 C CA . GLY A 1 372 ? -53.428 8.948 -51.560 1.00 46.60 ? 434 GLY A CA 1 +ATOM 2736 C C . GLY A 1 372 ? -52.044 9.205 -51.000 1.00 45.35 ? 434 GLY A C 1 +ATOM 2737 O O . GLY A 1 372 ? -51.136 8.379 -51.146 1.00 42.32 ? 434 GLY A O 1 +ATOM 2738 N N . PHE A 1 373 ? -51.861 10.381 -50.402 1.00 51.20 ? 435 PHE A N 1 +ATOM 2739 C CA . PHE A 1 373 ? -50.593 10.760 -49.781 1.00 49.07 ? 435 PHE A CA 1 +ATOM 2740 C C . PHE A 1 373 ? -49.454 10.658 -50.788 1.00 45.40 ? 435 PHE A C 1 +ATOM 2741 O O . PHE A 1 373 ? -48.430 10.015 -50.548 1.00 43.18 ? 435 PHE A O 1 +ATOM 2742 C CB . PHE A 1 373 ? -50.308 9.913 -48.539 1.00 45.24 ? 435 PHE A CB 1 +ATOM 2743 C CG . PHE A 1 373 ? -51.134 10.296 -47.352 1.00 43.06 ? 435 PHE A CG 1 +ATOM 2744 C CD1 . PHE A 1 373 ? -51.162 11.605 -46.909 1.00 48.73 ? 435 PHE A CD1 1 +ATOM 2745 C CD2 . PHE A 1 373 ? -51.909 9.357 -46.703 1.00 38.00 ? 435 PHE A CD2 1 +ATOM 2746 C CE1 . PHE A 1 373 ? -51.931 11.960 -45.821 1.00 48.97 ? 435 PHE A CE1 1 +ATOM 2747 C CE2 . PHE A 1 373 ? -52.678 9.708 -45.621 1.00 38.00 ? 435 PHE A CE2 1 +ATOM 2748 C CZ . PHE A 1 373 ? -52.692 11.009 -45.179 1.00 38.00 ? 435 PHE A CZ 1 +ATOM 2749 N N . GLY A 1 374 ? -49.659 11.276 -51.943 1.00 44.34 ? 436 GLY A N 1 +ATOM 2750 C CA . GLY A 1 374 ? -48.637 11.283 -52.962 1.00 46.77 ? 436 GLY A CA 1 +ATOM 2751 C C . GLY A 1 374 ? -48.201 12.676 -53.358 1.00 46.69 ? 436 GLY A C 1 +ATOM 2752 O O . GLY A 1 374 ? -47.110 12.858 -53.901 1.00 42.74 ? 436 GLY A O 1 +ATOM 2753 N N . ARG A 1 375 ? -49.034 13.673 -53.072 1.00 49.59 ? 437 ARG A N 1 +ATOM 2754 C CA . ARG A 1 375 ? -48.734 15.069 -53.385 1.00 49.48 ? 437 ARG A CA 1 +ATOM 2755 C C . ARG A 1 375 ? -48.930 15.881 -52.109 1.00 49.56 ? 437 ARG A C 1 +ATOM 2756 O O . ARG A 1 375 ? -50.059 16.230 -51.748 1.00 49.11 ? 437 ARG A O 1 +ATOM 2757 C CB . ARG A 1 375 ? -49.618 15.591 -54.516 1.00 57.35 ? 437 ARG A CB 1 +ATOM 2758 C CG . ARG A 1 375 ? -49.385 14.936 -55.869 1.00 56.69 ? 437 ARG A CG 1 +ATOM 2759 C CD . ARG A 1 375 ? -48.029 15.347 -56.430 1.00 65.52 ? 437 ARG A CD 1 +ATOM 2760 N NE . ARG A 1 375 ? -47.904 16.795 -56.599 1.00 73.17 ? 437 ARG A NE 1 +ATOM 2761 C CZ . ARG A 1 375 ? -48.259 17.458 -57.696 1.00 77.21 ? 437 ARG A CZ 1 +ATOM 2762 N NH1 . ARG A 1 375 ? -48.768 16.805 -58.735 1.00 70.09 ? 437 ARG A NH1 1 +ATOM 2763 N NH2 . ARG A 1 375 ? -48.106 18.776 -57.755 1.00 75.57 ? 437 ARG A NH2 1 +ATOM 2764 N N . HIS A 1 376 ? -47.835 16.175 -51.419 1.00 46.13 ? 438 HIS A N 1 +ATOM 2765 C CA . HIS A 1 376 ? -47.925 17.003 -50.227 1.00 47.24 ? 438 HIS A CA 1 +ATOM 2766 C C . HIS A 1 376 ? -47.914 18.487 -50.550 1.00 51.37 ? 438 HIS A C 1 +ATOM 2767 O O . HIS A 1 376 ? -48.254 19.299 -49.683 1.00 54.28 ? 438 HIS A O 1 +ATOM 2768 C CB . HIS A 1 376 ? -46.785 16.659 -49.273 1.00 46.57 ? 438 HIS A CB 1 +ATOM 2769 C CG . HIS A 1 376 ? -45.424 16.904 -49.841 1.00 40.46 ? 438 HIS A CG 1 +ATOM 2770 N ND1 . HIS A 1 376 ? -44.911 18.169 -50.026 1.00 38.47 ? 438 HIS A ND1 1 +ATOM 2771 C CD2 . HIS A 1 376 ? -44.473 16.044 -50.275 1.00 41.14 ? 438 HIS A CD2 1 +ATOM 2772 C CE1 . HIS A 1 376 ? -43.697 18.078 -50.536 1.00 47.02 ? 438 HIS A CE1 1 +ATOM 2773 N NE2 . HIS A 1 376 ? -43.408 16.799 -50.700 1.00 45.86 ? 438 HIS A NE2 1 +ATOM 2774 N N . SER A 1 377 ? -47.537 18.851 -51.771 1.00 55.66 ? 439 SER A N 1 +ATOM 2775 C CA . SER A 1 377 ? -47.472 20.239 -52.194 1.00 55.42 ? 439 SER A CA 1 +ATOM 2776 C C . SER A 1 377 ? -48.686 20.664 -53.010 1.00 57.69 ? 439 SER A C 1 +ATOM 2777 O O . SER A 1 377 ? -48.834 21.854 -53.300 1.00 67.27 ? 439 SER A O 1 +ATOM 2778 C CB . SER A 1 377 ? -46.183 20.464 -52.999 1.00 58.38 ? 439 SER A CB 1 +ATOM 2779 O OG . SER A 1 377 ? -46.115 21.769 -53.539 1.00 81.37 ? 439 SER A OG 1 +ATOM 2780 N N . HIS A 1 378 ? -49.562 19.733 -53.369 1.00 52.72 ? 440 HIS A N 1 +ATOM 2781 C CA . HIS A 1 378 ? -50.733 20.020 -54.182 1.00 49.19 ? 440 HIS A CA 1 +ATOM 2782 C C . HIS A 1 378 ? -51.985 19.499 -53.495 1.00 45.33 ? 440 HIS A C 1 +ATOM 2783 O O . HIS A 1 378 ? -51.968 18.432 -52.875 1.00 50.24 ? 440 HIS A O 1 +ATOM 2784 C CB . HIS A 1 378 ? -50.607 19.398 -55.572 1.00 59.23 ? 440 HIS A CB 1 +ATOM 2785 C CG . HIS A 1 378 ? -51.813 19.601 -56.434 1.00 66.28 ? 440 HIS A CG 1 +ATOM 2786 N ND1 . HIS A 1 378 ? -52.287 20.850 -56.772 1.00 69.91 ? 440 HIS A ND1 1 +ATOM 2787 C CD2 . HIS A 1 378 ? -52.658 18.710 -57.007 1.00 65.59 ? 440 HIS A CD2 1 +ATOM 2788 C CE1 . HIS A 1 378 ? -53.363 20.719 -57.528 1.00 68.15 ? 440 HIS A CE1 1 +ATOM 2789 N NE2 . HIS A 1 378 ? -53.611 19.431 -57.683 1.00 62.74 ? 440 HIS A NE2 1 +ATOM 2790 N N . ASP A 1 379 ? -53.065 20.264 -53.594 1.00 41.54 ? 441 ASP A N 1 +ATOM 2791 C CA . ASP A 1 379 ? -54.366 19.861 -53.081 1.00 44.28 ? 441 ASP A CA 1 +ATOM 2792 C C . ASP A 1 379 ? -55.320 19.798 -54.261 1.00 46.87 ? 441 ASP A C 1 +ATOM 2793 O O . ASP A 1 379 ? -55.489 20.791 -54.975 1.00 53.10 ? 441 ASP A O 1 +ATOM 2794 C CB . ASP A 1 379 ? -54.879 20.839 -52.022 1.00 50.36 ? 441 ASP A CB 1 +ATOM 2795 C CG . ASP A 1 379 ? -53.894 21.040 -50.876 1.00 56.57 ? 441 ASP A CG 1 +ATOM 2796 O OD1 . ASP A 1 379 ? -53.002 20.184 -50.678 1.00 59.01 ? 441 ASP A OD1 1 +ATOM 2797 O OD2 . ASP A 1 379 ? -54.018 22.065 -50.171 1.00 52.84 ? 441 ASP A OD2 1 +ATOM 2798 N N . GLU A 1 380 ? -55.900 18.629 -54.498 1.00 48.10 ? 442 GLU A N 1 +ATOM 2799 C CA . GLU A 1 380 ? -56.802 18.445 -55.632 1.00 51.14 ? 442 GLU A CA 1 +ATOM 2800 C C . GLU A 1 380 ? -58.231 18.707 -55.172 1.00 47.67 ? 442 GLU A C 1 +ATOM 2801 O O . GLU A 1 380 ? -58.870 17.845 -54.565 1.00 45.35 ? 442 GLU A O 1 +ATOM 2802 C CB . GLU A 1 380 ? -56.640 17.053 -56.227 1.00 56.53 ? 442 GLU A CB 1 +ATOM 2803 C CG . GLU A 1 380 ? -57.382 16.860 -57.541 1.00 61.21 ? 442 GLU A CG 1 +ATOM 2804 C CD . GLU A 1 380 ? -56.967 17.847 -58.616 1.00 54.94 ? 442 GLU A CD 1 +ATOM 2805 O OE1 . GLU A 1 380 ? -57.825 18.640 -59.052 1.00 49.70 ? 442 GLU A OE1 1 +ATOM 2806 O OE2 . GLU A 1 380 ? -55.782 17.843 -59.012 1.00 56.99 ? 442 GLU A OE2 1 +ATOM 2807 N N . ILE A 1 381 ? -58.745 19.898 -55.491 1.00 50.88 ? 443 ILE A N 1 +ATOM 2808 C CA . ILE A 1 381 ? -60.067 20.299 -55.021 1.00 49.82 ? 443 ILE A CA 1 +ATOM 2809 C C . ILE A 1 381 ? -61.178 19.594 -55.781 1.00 48.46 ? 443 ILE A C 1 +ATOM 2810 O O . ILE A 1 381 ? -62.326 19.583 -55.318 1.00 43.67 ? 443 ILE A O 1 +ATOM 2811 C CB . ILE A 1 381 ? -60.272 21.819 -55.135 1.00 48.08 ? 443 ILE A CB 1 +ATOM 2812 C CG1 . ILE A 1 381 ? -58.959 22.570 -54.888 1.00 50.36 ? 443 ILE A CG1 1 +ATOM 2813 C CG2 . ILE A 1 381 ? -61.353 22.282 -54.169 1.00 38.00 ? 443 ILE A CG2 1 +ATOM 2814 C CD1 . ILE A 1 381 ? -58.219 22.989 -56.162 1.00 47.84 ? 443 ILE A CD1 1 +ATOM 2815 N N . SER A 1 382 ? -60.876 19.023 -56.948 1.00 48.30 ? 444 SER A N 1 +ATOM 2816 C CA . SER A 1 382 ? -61.898 18.285 -57.672 1.00 50.94 ? 444 SER A CA 1 +ATOM 2817 C C . SER A 1 382 ? -62.389 17.082 -56.881 1.00 50.45 ? 444 SER A C 1 +ATOM 2818 O O . SER A 1 382 ? -63.536 16.661 -57.066 1.00 51.01 ? 444 SER A O 1 +ATOM 2819 C CB . SER A 1 382 ? -61.366 17.849 -59.042 1.00 56.94 ? 444 SER A CB 1 +ATOM 2820 O OG . SER A 1 382 ? -60.175 17.092 -58.923 1.00 55.57 ? 444 SER A OG 1 +ATOM 2821 N N . ILE A 1 383 ? -61.567 16.543 -55.975 1.00 46.82 ? 445 ILE A N 1 +ATOM 2822 C CA . ILE A 1 383 ? -62.037 15.460 -55.117 1.00 47.59 ? 445 ILE A CA 1 +ATOM 2823 C C . ILE A 1 383 ? -63.162 15.950 -54.226 1.00 45.06 ? 445 ILE A C 1 +ATOM 2824 O O . ILE A 1 383 ? -64.122 15.219 -53.956 1.00 44.50 ? 445 ILE A O 1 +ATOM 2825 C CB . ILE A 1 383 ? -60.877 14.879 -54.287 1.00 44.65 ? 445 ILE A CB 1 +ATOM 2826 C CG1 . ILE A 1 383 ? -59.688 14.553 -55.182 1.00 43.66 ? 445 ILE A CG1 1 +ATOM 2827 C CG2 . ILE A 1 383 ? -61.312 13.623 -53.564 1.00 50.43 ? 445 ILE A CG2 1 +ATOM 2828 C CD1 . ILE A 1 383 ? -58.475 14.113 -54.408 1.00 45.98 ? 445 ILE A CD1 1 +ATOM 2829 N N . LEU A 1 384 ? -63.087 17.201 -53.793 1.00 47.16 ? 446 LEU A N 1 +ATOM 2830 C CA . LEU A 1 384 ? -64.085 17.802 -52.925 1.00 51.45 ? 446 LEU A CA 1 +ATOM 2831 C C . LEU A 1 384 ? -65.346 18.210 -53.678 1.00 47.72 ? 446 LEU A C 1 +ATOM 2832 O O . LEU A 1 384 ? -66.243 18.804 -53.073 1.00 45.56 ? 446 LEU A O 1 +ATOM 2833 C CB . LEU A 1 384 ? -63.468 19.013 -52.216 1.00 55.10 ? 446 LEU A CB 1 +ATOM 2834 C CG . LEU A 1 384 ? -63.570 19.179 -50.698 1.00 47.40 ? 446 LEU A CG 1 +ATOM 2835 C CD1 . LEU A 1 384 ? -64.848 19.902 -50.344 1.00 57.60 ? 446 LEU A CD1 1 +ATOM 2836 C CD2 . LEU A 1 384 ? -63.525 17.849 -50.004 1.00 40.60 ? 446 LEU A CD2 1 +ATOM 2837 N N . SER A 1 385 ? -65.443 17.873 -54.964 1.00 49.10 ? 447 SER A N 1 +ATOM 2838 C CA . SER A 1 385 ? -66.608 18.252 -55.760 1.00 55.79 ? 447 SER A CA 1 +ATOM 2839 C C . SER A 1 385 ? -67.948 17.854 -55.151 1.00 57.54 ? 447 SER A C 1 +ATOM 2840 O O . SER A 1 385 ? -68.902 18.640 -55.285 1.00 58.96 ? 447 SER A O 1 +ATOM 2841 C CB . SER A 1 385 ? -66.499 17.656 -57.173 1.00 51.26 ? 447 SER A CB 1 +ATOM 2842 O OG . SER A 1 385 ? -65.503 18.311 -57.935 1.00 52.26 ? 447 SER A OG 1 +ATOM 2843 N N . PRO A 1 386 ? -68.112 16.685 -54.513 1.00 53.97 ? 448 PRO A N 1 +ATOM 2844 C CA . PRO A 1 386 ? -69.426 16.381 -53.913 1.00 49.30 ? 448 PRO A CA 1 +ATOM 2845 C C . PRO A 1 386 ? -69.868 17.420 -52.902 1.00 51.46 ? 448 PRO A C 1 +ATOM 2846 O O . PRO A 1 386 ? -71.022 17.867 -52.929 1.00 47.95 ? 448 PRO A O 1 +ATOM 2847 C CB . PRO A 1 386 ? -69.201 15.009 -53.267 1.00 51.03 ? 448 PRO A CB 1 +ATOM 2848 C CG . PRO A 1 386 ? -68.118 14.397 -54.061 1.00 56.34 ? 448 PRO A CG 1 +ATOM 2849 C CD . PRO A 1 386 ? -67.200 15.530 -54.413 1.00 51.97 ? 448 PRO A CD 1 +ATOM 2850 N N . LEU A 1 387 ? -68.974 17.805 -51.990 1.00 57.47 ? 449 LEU A N 1 +ATOM 2851 C CA . LEU A 1 387 ? -69.312 18.837 -51.020 1.00 54.99 ? 449 LEU A CA 1 +ATOM 2852 C C . LEU A 1 387 ? -69.450 20.195 -51.692 1.00 54.85 ? 449 LEU A C 1 +ATOM 2853 O O . LEU A 1 387 ? -70.334 20.980 -51.326 1.00 54.34 ? 449 LEU A O 1 +ATOM 2854 C CB . LEU A 1 387 ? -68.244 18.887 -49.929 1.00 42.74 ? 449 LEU A CB 1 +ATOM 2855 C CG . LEU A 1 387 ? -68.528 19.800 -48.741 1.00 41.42 ? 449 LEU A CG 1 +ATOM 2856 C CD1 . LEU A 1 387 ? -69.791 19.335 -48.025 1.00 42.56 ? 449 LEU A CD1 1 +ATOM 2857 C CD2 . LEU A 1 387 ? -67.342 19.838 -47.795 1.00 38.48 ? 449 LEU A CD2 1 +ATOM 2858 N N . SER A 1 388 ? -68.625 20.460 -52.710 1.00 54.71 ? 450 SER A N 1 +ATOM 2859 C CA . SER A 1 388 ? -68.679 21.743 -53.400 1.00 52.20 ? 450 SER A CA 1 +ATOM 2860 C C . SER A 1 388 ? -70.026 21.943 -54.077 1.00 54.74 ? 450 SER A C 1 +ATOM 2861 O O . SER A 1 388 ? -70.625 23.021 -53.982 1.00 62.20 ? 450 SER A O 1 +ATOM 2862 C CB . SER A 1 388 ? -67.557 21.833 -54.438 1.00 50.58 ? 450 SER A CB 1 +ATOM 2863 O OG . SER A 1 388 ? -66.280 21.618 -53.862 1.00 49.56 ? 450 SER A OG 1 +ATOM 2864 N N . GLN A 1 389 ? -70.528 20.910 -54.747 1.00 58.73 ? 451 GLN A N 1 +ATOM 2865 C CA . GLN A 1 389 ? -71.709 21.056 -55.586 1.00 59.08 ? 451 GLN A CA 1 +ATOM 2866 C C . GLN A 1 389 ? -73.002 20.718 -54.852 1.00 54.11 ? 451 GLN A C 1 +ATOM 2867 O O . GLN A 1 389 ? -73.985 21.453 -54.982 1.00 49.55 ? 451 GLN A O 1 +ATOM 2868 C CB . GLN A 1 389 ? -71.540 20.199 -56.843 1.00 58.13 ? 451 GLN A CB 1 +ATOM 2869 C CG . GLN A 1 389 ? -70.217 20.500 -57.557 1.00 55.84 ? 451 GLN A CG 1 +ATOM 2870 C CD . GLN A 1 389 ? -69.911 19.555 -58.696 1.00 60.59 ? 451 GLN A CD 1 +ATOM 2871 O OE1 . GLN A 1 389 ? -70.128 18.350 -58.596 1.00 59.98 ? 451 GLN A OE1 1 +ATOM 2872 N NE2 . GLN A 1 389 ? -69.386 20.102 -59.789 1.00 62.29 ? 451 GLN A NE2 1 +ATOM 2873 N N . CYS A 1 390 ? -73.022 19.642 -54.060 1.00 62.01 ? 452 CYS A N 1 +ATOM 2874 C CA . CYS A 1 390 ? -74.238 19.306 -53.319 1.00 65.27 ? 452 CYS A CA 1 +ATOM 2875 C C . CYS A 1 390 ? -74.488 20.290 -52.193 1.00 65.96 ? 452 CYS A C 1 +ATOM 2876 O O . CYS A 1 390 ? -75.641 20.649 -51.917 1.00 56.84 ? 452 CYS A O 1 +ATOM 2877 C CB . CYS A 1 390 ? -74.146 17.897 -52.745 1.00 62.77 ? 452 CYS A CB 1 +ATOM 2878 S SG . CYS A 1 390 ? -73.911 16.639 -53.977 1.00 75.24 ? 452 CYS A SG 1 +ATOM 2879 N N . CYS A 1 391 ? -73.419 20.719 -51.529 1.00 68.62 ? 453 CYS A N 1 +ATOM 2880 C CA . CYS A 1 391 ? -73.471 21.649 -50.409 1.00 68.29 ? 453 CYS A CA 1 +ATOM 2881 C C . CYS A 1 391 ? -74.426 21.134 -49.324 1.00 67.03 ? 453 CYS A C 1 +ATOM 2882 O O . CYS A 1 391 ? -75.521 21.651 -49.102 1.00 62.57 ? 453 CYS A O 1 +ATOM 2883 C CB . CYS A 1 391 ? -73.834 23.057 -50.901 1.00 65.97 ? 453 CYS A CB 1 +ATOM 2884 S SG . CYS A 1 391 ? -73.811 24.338 -49.611 1.00 105.53 ? 453 CYS A SG 1 +ATOM 2885 N N . MET A 1 392 ? -73.979 20.047 -48.686 1.00 62.40 ? 454 MET A N 1 +ATOM 2886 C CA . MET A 1 392 ? -74.597 19.514 -47.474 1.00 61.18 ? 454 MET A CA 1 +ATOM 2887 C C . MET A 1 392 ? -73.675 18.491 -46.819 1.00 59.44 ? 454 MET A C 1 +ATOM 2888 O O . MET A 1 392 ? -73.097 17.643 -47.504 1.00 59.14 ? 454 MET A O 1 +ATOM 2889 C CB . MET A 1 392 ? -75.974 18.900 -47.761 1.00 62.02 ? 454 MET A CB 1 +ATOM 2890 C CG . MET A 1 392 ? -76.054 17.982 -48.960 1.00 60.59 ? 454 MET A CG 1 +ATOM 2891 S SD . MET A 1 392 ? -77.770 17.621 -49.416 1.00 74.57 ? 454 MET A SD 1 +ATOM 2892 C CE . MET A 1 392 ? -78.513 17.253 -47.832 1.00 52.98 ? 454 MET A CE 1 +ATOM 2893 N N . ILE A 1 393 ? -73.508 18.584 -45.496 1.00 63.05 ? 455 ILE A N 1 +ATOM 2894 C CA . ILE A 1 393 ? -72.596 17.732 -44.738 1.00 55.11 ? 455 ILE A CA 1 +ATOM 2895 C C . ILE A 1 393 ? -73.297 17.279 -43.461 1.00 57.47 ? 455 ILE A C 1 +ATOM 2896 O O . ILE A 1 393 ? -74.163 17.979 -42.926 1.00 57.35 ? 455 ILE A O 1 +ATOM 2897 C CB . ILE A 1 393 ? -71.267 18.456 -44.415 1.00 45.40 ? 455 ILE A CB 1 +ATOM 2898 C CG1 . ILE A 1 393 ? -70.288 17.517 -43.717 1.00 39.22 ? 455 ILE A CG1 1 +ATOM 2899 C CG2 . ILE A 1 393 ? -71.506 19.678 -43.552 1.00 48.46 ? 455 ILE A CG2 1 +ATOM 2900 C CD1 . ILE A 1 393 ? -68.991 18.181 -43.338 1.00 40.29 ? 455 ILE A CD1 1 +ATOM 2901 N N . LYS A 1 394 ? -72.931 16.088 -42.984 1.00 57.72 ? 456 LYS A N 1 +ATOM 2902 C CA . LYS A 1 394 ? -73.538 15.534 -41.780 1.00 54.96 ? 456 LYS A CA 1 +ATOM 2903 C C . LYS A 1 394 ? -73.123 16.313 -40.534 1.00 52.72 ? 456 LYS A C 1 +ATOM 2904 O O . LYS A 1 394 ? -71.985 16.775 -40.408 1.00 49.72 ? 456 LYS A O 1 +ATOM 2905 C CB . LYS A 1 394 ? -73.159 14.063 -41.612 1.00 51.09 ? 456 LYS A CB 1 +ATOM 2906 C CG . LYS A 1 394 ? -73.283 13.243 -42.882 1.00 60.67 ? 456 LYS A CG 1 +ATOM 2907 C CD . LYS A 1 394 ? -73.583 11.773 -42.589 1.00 64.05 ? 456 LYS A CD 1 +ATOM 2908 C CE . LYS A 1 394 ? -72.488 11.104 -41.777 1.00 60.35 ? 456 LYS A CE 1 +ATOM 2909 N NZ . LYS A 1 394 ? -72.669 9.623 -41.741 1.00 54.96 ? 456 LYS A NZ 1 +ATOM 2910 N N . LYS A 1 395 ? -74.055 16.403 -39.581 1.00 55.20 ? 457 LYS A N 1 +ATOM 2911 C CA . LYS A 1 395 ? -73.799 17.145 -38.349 1.00 52.85 ? 457 LYS A CA 1 +ATOM 2912 C C . LYS A 1 395 ? -72.564 16.610 -37.639 1.00 45.84 ? 457 LYS A C 1 +ATOM 2913 O O . LYS A 1 395 ? -71.623 17.360 -37.359 1.00 41.94 ? 457 LYS A O 1 +ATOM 2914 C CB . LYS A 1 395 ? -75.020 17.051 -37.430 1.00 59.04 ? 457 LYS A CB 1 +ATOM 2915 C CG . LYS A 1 395 ? -74.928 17.832 -36.123 1.00 51.88 ? 457 LYS A CG 1 +ATOM 2916 C CD . LYS A 1 395 ? -75.270 19.293 -36.332 1.00 54.26 ? 457 LYS A CD 1 +ATOM 2917 C CE . LYS A 1 395 ? -75.831 19.927 -35.070 1.00 54.83 ? 457 LYS A CE 1 +ATOM 2918 N NZ . LYS A 1 395 ? -76.266 21.330 -35.337 1.00 53.20 ? 457 LYS A NZ 1 +ATOM 2919 N N . LYS A 1 396 ? -72.536 15.295 -37.395 1.00 49.35 ? 458 LYS A N 1 +ATOM 2920 C CA . LYS A 1 396 ? -71.413 14.658 -36.710 1.00 47.85 ? 458 LYS A CA 1 +ATOM 2921 C C . LYS A 1 396 ? -70.094 14.902 -37.435 1.00 50.29 ? 458 LYS A C 1 +ATOM 2922 O O . LYS A 1 396 ? -69.067 15.171 -36.797 1.00 42.79 ? 458 LYS A O 1 +ATOM 2923 C CB . LYS A 1 396 ? -71.682 13.155 -36.572 1.00 46.51 ? 458 LYS A CB 1 +ATOM 2924 C CG . LYS A 1 396 ? -70.474 12.328 -36.125 1.00 51.69 ? 458 LYS A CG 1 +ATOM 2925 C CD . LYS A 1 396 ? -70.832 10.857 -35.909 1.00 50.44 ? 458 LYS A CD 1 +ATOM 2926 C CE . LYS A 1 396 ? -69.585 10.003 -35.721 1.00 51.91 ? 458 LYS A CE 1 +ATOM 2927 N NZ . LYS A 1 396 ? -69.440 9.544 -34.315 1.00 61.80 ? 458 LYS A NZ 1 +ATOM 2928 N N . THR A 1 397 ? -70.091 14.780 -38.764 1.00 55.70 ? 459 THR A N 1 +ATOM 2929 C CA . THR A 1 397 ? -68.851 14.957 -39.514 1.00 52.57 ? 459 THR A CA 1 +ATOM 2930 C C . THR A 1 397 ? -68.314 16.373 -39.365 1.00 47.69 ? 459 THR A C 1 +ATOM 2931 O O . THR A 1 397 ? -67.102 16.577 -39.236 1.00 42.91 ? 459 THR A O 1 +ATOM 2932 C CB . THR A 1 397 ? -69.071 14.623 -40.989 1.00 46.02 ? 459 THR A CB 1 +ATOM 2933 O OG1 . THR A 1 397 ? -69.633 13.311 -41.105 1.00 45.14 ? 459 THR A OG1 1 +ATOM 2934 C CG2 . THR A 1 397 ? -67.750 14.659 -41.734 1.00 38.27 ? 459 THR A CG2 1 +ATOM 2935 N N . LEU A 1 398 ? -69.204 17.364 -39.366 1.00 48.50 ? 460 LEU A N 1 +ATOM 2936 C CA . LEU A 1 398 ? -68.756 18.749 -39.284 1.00 50.78 ? 460 LEU A CA 1 +ATOM 2937 C C . LEU A 1 398 ? -68.167 19.061 -37.914 1.00 49.29 ? 460 LEU A C 1 +ATOM 2938 O O . LEU A 1 398 ? -67.170 19.786 -37.811 1.00 43.40 ? 460 LEU A O 1 +ATOM 2939 C CB . LEU A 1 398 ? -69.924 19.681 -39.607 1.00 50.04 ? 460 LEU A CB 1 +ATOM 2940 C CG . LEU A 1 398 ? -69.676 21.185 -39.594 1.00 43.14 ? 460 LEU A CG 1 +ATOM 2941 C CD1 . LEU A 1 398 ? -68.456 21.521 -40.429 1.00 43.06 ? 460 LEU A CD1 1 +ATOM 2942 C CD2 . LEU A 1 398 ? -70.912 21.894 -40.131 1.00 38.00 ? 460 LEU A CD2 1 +ATOM 2943 N N . LEU A 1 399 ? -68.756 18.496 -36.855 1.00 53.52 ? 461 LEU A N 1 +ATOM 2944 C CA . LEU A 1 399 ? -68.273 18.753 -35.501 1.00 45.67 ? 461 LEU A CA 1 +ATOM 2945 C C . LEU A 1 399 ? -66.880 18.169 -35.291 1.00 39.37 ? 461 LEU A C 1 +ATOM 2946 O O . LEU A 1 399 ? -66.018 18.814 -34.683 1.00 38.00 ? 461 LEU A O 1 +ATOM 2947 C CB . LEU A 1 399 ? -69.270 18.195 -34.483 1.00 38.00 ? 461 LEU A CB 1 +ATOM 2948 C CG . LEU A 1 399 ? -70.698 18.750 -34.592 1.00 38.00 ? 461 LEU A CG 1 +ATOM 2949 C CD1 . LEU A 1 399 ? -71.622 18.147 -33.551 1.00 38.00 ? 461 LEU A CD1 1 +ATOM 2950 C CD2 . LEU A 1 399 ? -70.709 20.263 -34.499 1.00 38.00 ? 461 LEU A CD2 1 +ATOM 2951 N N . HIS A 1 400 ? -66.634 16.957 -35.797 1.00 38.57 ? 462 HIS A N 1 +ATOM 2952 C CA . HIS A 1 400 ? -65.302 16.372 -35.682 1.00 40.51 ? 462 HIS A CA 1 +ATOM 2953 C C . HIS A 1 400 ? -64.273 17.161 -36.481 1.00 40.27 ? 462 HIS A C 1 +ATOM 2954 O O . HIS A 1 400 ? -63.106 17.243 -36.080 1.00 38.00 ? 462 HIS A O 1 +ATOM 2955 C CB . HIS A 1 400 ? -65.318 14.908 -36.132 1.00 44.09 ? 462 HIS A CB 1 +ATOM 2956 C CG . HIS A 1 400 ? -66.012 13.981 -35.180 1.00 45.92 ? 462 HIS A CG 1 +ATOM 2957 N ND1 . HIS A 1 400 ? -65.330 13.236 -34.241 1.00 43.15 ? 462 HIS A ND1 1 +ATOM 2958 C CD2 . HIS A 1 400 ? -67.320 13.663 -35.035 1.00 46.21 ? 462 HIS A CD2 1 +ATOM 2959 C CE1 . HIS A 1 400 ? -66.191 12.511 -33.548 1.00 47.94 ? 462 HIS A CE1 1 +ATOM 2960 N NE2 . HIS A 1 400 ? -67.405 12.752 -34.010 1.00 52.04 ? 462 HIS A NE2 1 +ATOM 2961 N N . LEU A 1 401 ? -64.678 17.719 -37.622 1.00 43.63 ? 463 LEU A N 1 +ATOM 2962 C CA . LEU A 1 401 ? -63.763 18.520 -38.432 1.00 47.62 ? 463 LEU A CA 1 +ATOM 2963 C C . LEU A 1 401 ? -63.435 19.845 -37.755 1.00 45.75 ? 463 LEU A C 1 +ATOM 2964 O O . LEU A 1 401 ? -62.271 20.267 -37.733 1.00 40.00 ? 463 LEU A O 1 +ATOM 2965 C CB . LEU A 1 401 ? -64.369 18.764 -39.814 1.00 46.01 ? 463 LEU A CB 1 +ATOM 2966 C CG . LEU A 1 401 ? -64.507 17.546 -40.729 1.00 43.09 ? 463 LEU A CG 1 +ATOM 2967 C CD1 . LEU A 1 401 ? -65.074 17.946 -42.085 1.00 43.62 ? 463 LEU A CD1 1 +ATOM 2968 C CD2 . LEU A 1 401 ? -63.163 16.854 -40.889 1.00 38.00 ? 463 LEU A CD2 1 +ATOM 2969 N N . GLN A 1 402 ? -64.453 20.521 -37.213 1.00 44.44 ? 464 GLN A N 1 +ATOM 2970 C CA . GLN A 1 402 ? -64.216 21.774 -36.507 1.00 43.91 ? 464 GLN A CA 1 +ATOM 2971 C C . GLN A 1 402 ? -63.290 21.562 -35.316 1.00 45.23 ? 464 GLN A C 1 +ATOM 2972 O O . GLN A 1 402 ? -62.362 22.350 -35.090 1.00 41.78 ? 464 GLN A O 1 +ATOM 2973 C CB . GLN A 1 402 ? -65.553 22.376 -36.063 1.00 38.00 ? 464 GLN A CB 1 +ATOM 2974 C CG . GLN A 1 402 ? -66.358 23.004 -37.193 1.00 40.90 ? 464 GLN A CG 1 +ATOM 2975 C CD . GLN A 1 402 ? -67.731 23.481 -36.757 1.00 47.68 ? 464 GLN A CD 1 +ATOM 2976 O OE1 . GLN A 1 402 ? -68.172 23.205 -35.644 1.00 63.23 ? 464 GLN A OE1 1 +ATOM 2977 N NE2 . GLN A 1 402 ? -68.407 24.220 -37.630 1.00 53.51 ? 464 GLN A NE2 1 +ATOM 2978 N N . LEU A 1 403 ? -63.507 20.477 -34.568 1.00 47.68 ? 465 LEU A N 1 +ATOM 2979 C CA . LEU A 1 403 ? -62.684 20.181 -33.400 1.00 44.26 ? 465 LEU A CA 1 +ATOM 2980 C C . LEU A 1 403 ? -61.232 19.958 -33.795 1.00 42.39 ? 465 LEU A C 1 +ATOM 2981 O O . LEU A 1 403 ? -60.313 20.429 -33.114 1.00 45.57 ? 465 LEU A O 1 +ATOM 2982 C CB . LEU A 1 403 ? -63.241 18.949 -32.684 1.00 38.72 ? 465 LEU A CB 1 +ATOM 2983 C CG . LEU A 1 403 ? -62.843 18.606 -31.248 1.00 38.00 ? 465 LEU A CG 1 +ATOM 2984 C CD1 . LEU A 1 403 ? -63.853 17.638 -30.662 1.00 38.00 ? 465 LEU A CD1 1 +ATOM 2985 C CD2 . LEU A 1 403 ? -61.478 18.013 -31.182 1.00 38.80 ? 465 LEU A CD2 1 +ATOM 2986 N N . LEU A 1 404 ? -61.004 19.224 -34.879 1.00 42.01 ? 466 LEU A N 1 +ATOM 2987 C CA . LEU A 1 404 ? -59.648 18.936 -35.321 1.00 47.65 ? 466 LEU A CA 1 +ATOM 2988 C C . LEU A 1 404 ? -58.939 20.155 -35.899 1.00 50.90 ? 466 LEU A C 1 +ATOM 2989 O O . LEU A 1 404 ? -57.766 20.044 -36.278 1.00 48.19 ? 466 LEU A O 1 +ATOM 2990 C CB . LEU A 1 404 ? -59.682 17.799 -36.340 1.00 44.83 ? 466 LEU A CB 1 +ATOM 2991 C CG . LEU A 1 404 ? -59.958 16.427 -35.721 1.00 40.85 ? 466 LEU A CG 1 +ATOM 2992 C CD1 . LEU A 1 404 ? -60.410 15.458 -36.777 1.00 42.92 ? 466 LEU A CD1 1 +ATOM 2993 C CD2 . LEU A 1 404 ? -58.705 15.903 -35.029 1.00 40.14 ? 466 LEU A CD2 1 +ATOM 2994 N N . ALA A 1 405 ? -59.601 21.310 -35.959 1.00 49.08 ? 467 ALA A N 1 +ATOM 2995 C CA . ALA A 1 405 ? -58.959 22.538 -36.403 1.00 47.61 ? 467 ALA A CA 1 +ATOM 2996 C C . ALA A 1 405 ? -58.388 23.352 -35.250 1.00 50.37 ? 467 ALA A C 1 +ATOM 2997 O O . ALA A 1 405 ? -57.594 24.269 -35.488 1.00 52.78 ? 467 ALA A O 1 +ATOM 2998 C CB . ALA A 1 405 ? -59.952 23.395 -37.193 1.00 47.31 ? 467 ALA A CB 1 +ATOM 2999 N N . GLN A 1 406 ? -58.751 23.023 -34.015 1.00 44.97 ? 468 GLN A N 1 +ATOM 3000 C CA . GLN A 1 406 ? -58.276 23.736 -32.840 1.00 43.06 ? 468 GLN A CA 1 +ATOM 3001 C C . GLN A 1 406 ? -56.939 23.163 -32.397 1.00 43.44 ? 468 GLN A C 1 +ATOM 3002 O O . GLN A 1 406 ? -56.732 21.950 -32.438 1.00 48.74 ? 468 GLN A O 1 +ATOM 3003 C CB . GLN A 1 406 ? -59.305 23.619 -31.722 1.00 45.92 ? 468 GLN A CB 1 +ATOM 3004 C CG . GLN A 1 406 ? -60.611 24.294 -32.077 1.00 48.42 ? 468 GLN A CG 1 +ATOM 3005 C CD . GLN A 1 406 ? -61.785 23.694 -31.348 1.00 51.21 ? 468 GLN A CD 1 +ATOM 3006 O OE1 . GLN A 1 406 ? -61.619 22.916 -30.406 1.00 47.54 ? 468 GLN A OE1 1 +ATOM 3007 N NE2 . GLN A 1 406 ? -62.987 24.055 -31.777 1.00 52.28 ? 468 GLN A NE2 1 +ATOM 3008 N N . ALA A 1 407 ? -56.037 24.046 -31.960 1.00 46.62 ? 469 ALA A N 1 +ATOM 3009 C CA . ALA A 1 407 ? -54.660 23.639 -31.688 1.00 46.62 ? 469 ALA A CA 1 +ATOM 3010 C C . ALA A 1 407 ? -54.574 22.568 -30.607 1.00 48.91 ? 469 ALA A C 1 +ATOM 3011 O O . ALA A 1 407 ? -53.617 21.784 -30.588 1.00 47.90 ? 469 ALA A O 1 +ATOM 3012 C CB . ALA A 1 407 ? -53.820 24.852 -31.293 1.00 49.08 ? 469 ALA A CB 1 +ATOM 3013 N N . ASP A 1 408 ? -55.553 22.517 -29.700 1.00 51.19 ? 470 ASP A N 1 +ATOM 3014 C CA . ASP A 1 408 ? -55.527 21.521 -28.631 1.00 50.82 ? 470 ASP A CA 1 +ATOM 3015 C C . ASP A 1 408 ? -55.676 20.102 -29.169 1.00 50.29 ? 470 ASP A C 1 +ATOM 3016 O O . ASP A 1 408 ? -55.216 19.144 -28.535 1.00 46.04 ? 470 ASP A O 1 +ATOM 3017 C CB . ASP A 1 408 ? -56.635 21.818 -27.626 1.00 49.28 ? 470 ASP A CB 1 +ATOM 3018 C CG . ASP A 1 408 ? -56.454 23.153 -26.954 1.00 55.26 ? 470 ASP A CG 1 +ATOM 3019 O OD1 . ASP A 1 408 ? -55.436 23.328 -26.252 1.00 60.45 ? 470 ASP A OD1 1 +ATOM 3020 O OD2 . ASP A 1 408 ? -57.323 24.029 -27.138 1.00 56.96 ? 470 ASP A OD2 1 +ATOM 3021 N N . TYR A 1 409 ? -56.333 19.946 -30.312 1.00 54.13 ? 471 TYR A N 1 +ATOM 3022 C CA . TYR A 1 409 ? -56.484 18.656 -30.968 1.00 46.62 ? 471 TYR A CA 1 +ATOM 3023 C C . TYR A 1 409 ? -56.359 18.835 -32.477 1.00 48.97 ? 471 TYR A C 1 +ATOM 3024 O O . TYR A 1 409 ? -57.238 18.441 -33.244 1.00 42.37 ? 471 TYR A O 1 +ATOM 3025 C CB . TYR A 1 409 ? -57.821 17.989 -30.649 1.00 44.96 ? 471 TYR A CB 1 +ATOM 3026 C CG . TYR A 1 409 ? -58.556 18.417 -29.391 1.00 44.70 ? 471 TYR A CG 1 +ATOM 3027 C CD1 . TYR A 1 409 ? -59.309 19.584 -29.356 1.00 49.89 ? 471 TYR A CD1 1 +ATOM 3028 C CD2 . TYR A 1 409 ? -58.562 17.607 -28.266 1.00 49.72 ? 471 TYR A CD2 1 +ATOM 3029 C CE1 . TYR A 1 409 ? -60.019 19.944 -28.222 1.00 58.55 ? 471 TYR A CE1 1 +ATOM 3030 C CE2 . TYR A 1 409 ? -59.264 17.962 -27.128 1.00 52.72 ? 471 TYR A CE2 1 +ATOM 3031 C CZ . TYR A 1 409 ? -59.989 19.130 -27.109 1.00 56.87 ? 471 TYR A CZ 1 +ATOM 3032 O OH . TYR A 1 409 ? -60.681 19.483 -25.970 1.00 57.52 ? 471 TYR A OH 1 +ATOM 3033 N N . ARG A 1 410 ? -55.284 19.479 -32.926 1.00 49.31 ? 472 ARG A N 1 +ATOM 3034 C CA . ARG A 1 410 ? -55.157 19.737 -34.354 1.00 51.69 ? 472 ARG A CA 1 +ATOM 3035 C C . ARG A 1 410 ? -54.831 18.455 -35.115 1.00 50.94 ? 472 ARG A C 1 +ATOM 3036 O O . ARG A 1 410 ? -54.125 17.569 -34.623 1.00 47.74 ? 472 ARG A O 1 +ATOM 3037 C CB . ARG A 1 410 ? -54.105 20.805 -34.630 1.00 50.73 ? 472 ARG A CB 1 +ATOM 3038 C CG . ARG A 1 410 ? -52.697 20.444 -34.238 1.00 50.83 ? 472 ARG A CG 1 +ATOM 3039 C CD . ARG A 1 410 ? -51.742 21.374 -34.959 1.00 52.03 ? 472 ARG A CD 1 +ATOM 3040 N NE . ARG A 1 410 ? -52.353 22.679 -35.196 1.00 50.15 ? 472 ARG A NE 1 +ATOM 3041 C CZ . ARG A 1 410 ? -52.200 23.734 -34.403 1.00 58.14 ? 472 ARG A CZ 1 +ATOM 3042 N NH1 . ARG A 1 410 ? -51.440 23.653 -33.317 1.00 55.67 ? 472 ARG A NH1 1 +ATOM 3043 N NH2 . ARG A 1 410 ? -52.804 24.876 -34.704 1.00 61.83 ? 472 ARG A NH2 1 +ATOM 3044 N N . LEU A 1 411 ? -55.319 18.393 -36.358 1.00 47.99 ? 473 LEU A N 1 +ATOM 3045 C CA . LEU A 1 411 ? -55.321 17.135 -37.098 1.00 43.00 ? 473 LEU A CA 1 +ATOM 3046 C C . LEU A 1 411 ? -53.913 16.619 -37.352 1.00 38.00 ? 473 LEU A C 1 +ATOM 3047 O O . LEU A 1 411 ? -53.698 15.404 -37.373 1.00 38.00 ? 473 LEU A O 1 +ATOM 3048 C CB . LEU A 1 411 ? -56.069 17.310 -38.420 1.00 38.98 ? 473 LEU A CB 1 +ATOM 3049 C CG . LEU A 1 411 ? -56.238 16.066 -39.291 1.00 38.00 ? 473 LEU A CG 1 +ATOM 3050 C CD1 . LEU A 1 411 ? -56.926 14.967 -38.513 1.00 38.00 ? 473 LEU A CD1 1 +ATOM 3051 C CD2 . LEU A 1 411 ? -57.036 16.407 -40.529 1.00 38.00 ? 473 LEU A CD2 1 +ATOM 3052 N N . SER A 1 412 ? -52.943 17.513 -37.543 1.00 38.45 ? 474 SER A N 1 +ATOM 3053 C CA . SER A 1 412 ? -51.589 17.054 -37.833 1.00 44.02 ? 474 SER A CA 1 +ATOM 3054 C C . SER A 1 412 ? -50.947 16.411 -36.614 1.00 41.39 ? 474 SER A C 1 +ATOM 3055 O O . SER A 1 412 ? -50.201 15.435 -36.743 1.00 44.72 ? 474 SER A O 1 +ATOM 3056 C CB . SER A 1 412 ? -50.717 18.205 -38.330 1.00 51.62 ? 474 SER A CB 1 +ATOM 3057 O OG . SER A 1 412 ? -50.652 19.254 -37.382 1.00 54.24 ? 474 SER A OG 1 +ATOM 3058 N N . ASP A 1 413 ? -51.181 16.972 -35.427 1.00 40.74 ? 475 ASP A N 1 +ATOM 3059 C CA . ASP A 1 413 ? -50.502 16.473 -34.237 1.00 43.06 ? 475 ASP A CA 1 +ATOM 3060 C C . ASP A 1 413 ? -51.069 15.132 -33.777 1.00 41.70 ? 475 ASP A C 1 +ATOM 3061 O O . ASP A 1 413 ? -50.311 14.251 -33.351 1.00 38.91 ? 475 ASP A O 1 +ATOM 3062 C CB . ASP A 1 413 ? -50.571 17.515 -33.123 1.00 50.73 ? 475 ASP A CB 1 +ATOM 3063 C CG . ASP A 1 413 ? -49.637 18.692 -33.368 1.00 52.39 ? 475 ASP A CG 1 +ATOM 3064 O OD1 . ASP A 1 413 ? -48.668 18.531 -34.142 1.00 55.82 ? 475 ASP A OD1 1 +ATOM 3065 O OD2 . ASP A 1 413 ? -49.859 19.772 -32.781 1.00 51.62 ? 475 ASP A OD2 1 +ATOM 3066 N N . VAL A 1 414 ? -52.395 14.961 -33.836 1.00 41.29 ? 476 VAL A N 1 +ATOM 3067 C CA . VAL A 1 414 ? -53.007 13.702 -33.410 1.00 38.93 ? 476 VAL A CA 1 +ATOM 3068 C C . VAL A 1 414 ? -52.695 12.572 -34.391 1.00 43.86 ? 476 VAL A C 1 +ATOM 3069 O O . VAL A 1 414 ? -52.631 11.400 -33.998 1.00 43.82 ? 476 VAL A O 1 +ATOM 3070 C CB . VAL A 1 414 ? -54.525 13.885 -33.222 1.00 38.00 ? 476 VAL A CB 1 +ATOM 3071 C CG1 . VAL A 1 414 ? -54.804 14.862 -32.098 1.00 38.00 ? 476 VAL A CG1 1 +ATOM 3072 C CG2 . VAL A 1 414 ? -55.172 14.366 -34.508 1.00 39.75 ? 476 VAL A CG2 1 +ATOM 3073 N N . MET A 1 415 ? -52.507 12.896 -35.673 1.00 45.82 ? 477 MET A N 1 +ATOM 3074 C CA . MET A 1 415 ? -52.058 11.903 -36.644 1.00 38.00 ? 477 MET A CA 1 +ATOM 3075 C C . MET A 1 415 ? -50.596 11.551 -36.419 1.00 38.00 ? 477 MET A C 1 +ATOM 3076 O O . MET A 1 415 ? -50.227 10.375 -36.399 1.00 38.00 ? 477 MET A O 1 +ATOM 3077 C CB . MET A 1 415 ? -52.266 12.429 -38.062 1.00 38.00 ? 477 MET A CB 1 +ATOM 3078 C CG . MET A 1 415 ? -53.683 12.291 -38.568 1.00 39.68 ? 477 MET A CG 1 +ATOM 3079 S SD . MET A 1 415 ? -54.084 10.602 -39.026 1.00 47.94 ? 477 MET A SD 1 +ATOM 3080 C CE . MET A 1 415 ? -52.982 10.356 -40.410 1.00 41.92 ? 477 MET A CE 1 +ATOM 3081 N N . ARG A 1 416 ? -49.744 12.567 -36.282 1.00 38.00 ? 478 ARG A N 1 +ATOM 3082 C CA . ARG A 1 416 ? -48.326 12.333 -36.035 1.00 38.00 ? 478 ARG A CA 1 +ATOM 3083 C C . ARG A 1 416 ? -48.116 11.402 -34.854 1.00 41.98 ? 478 ARG A C 1 +ATOM 3084 O O . ARG A 1 416 ? -47.268 10.504 -34.902 1.00 47.19 ? 478 ARG A O 1 +ATOM 3085 C CB . ARG A 1 416 ? -47.619 13.663 -35.782 1.00 44.12 ? 478 ARG A CB 1 +ATOM 3086 C CG . ARG A 1 416 ? -46.143 13.560 -35.440 1.00 40.48 ? 478 ARG A CG 1 +ATOM 3087 C CD . ARG A 1 416 ? -45.698 14.812 -34.706 1.00 41.83 ? 478 ARG A CD 1 +ATOM 3088 N NE . ARG A 1 416 ? -46.462 15.978 -35.147 1.00 50.19 ? 478 ARG A NE 1 +ATOM 3089 C CZ . ARG A 1 416 ? -46.183 16.688 -36.238 1.00 51.74 ? 478 ARG A CZ 1 +ATOM 3090 N NH1 . ARG A 1 416 ? -45.153 16.348 -37.003 1.00 46.69 ? 478 ARG A NH1 1 +ATOM 3091 N NH2 . ARG A 1 416 ? -46.938 17.733 -36.569 1.00 44.67 ? 478 ARG A NH2 1 +ATOM 3092 N N . GLU A 1 417 ? -48.894 11.590 -33.786 1.00 43.06 ? 479 GLU A N 1 +ATOM 3093 C CA . GLU A 1 417 ? -48.723 10.760 -32.600 1.00 47.11 ? 479 GLU A CA 1 +ATOM 3094 C C . GLU A 1 417 ? -49.270 9.353 -32.832 1.00 48.27 ? 479 GLU A C 1 +ATOM 3095 O O . GLU A 1 417 ? -48.582 8.361 -32.557 1.00 44.62 ? 479 GLU A O 1 +ATOM 3096 C CB . GLU A 1 417 ? -49.410 11.432 -31.405 1.00 49.65 ? 479 GLU A CB 1 +ATOM 3097 C CG . GLU A 1 417 ? -49.059 10.854 -30.037 1.00 62.24 ? 479 GLU A CG 1 +ATOM 3098 C CD . GLU A 1 417 ? -49.786 11.549 -28.886 1.00 65.75 ? 479 GLU A CD 1 +ATOM 3099 O OE1 . GLU A 1 417 ? -50.377 12.631 -29.101 1.00 59.13 ? 479 GLU A OE1 1 +ATOM 3100 O OE2 . GLU A 1 417 ? -49.764 11.007 -27.759 1.00 71.64 ? 479 GLU A OE2 1 +ATOM 3101 N N . SER A 1 418 ? -50.471 9.247 -33.418 1.00 44.02 ? 480 SER A N 1 +ATOM 3102 C CA . SER A 1 418 ? -51.086 7.943 -33.648 1.00 38.00 ? 480 SER A CA 1 +ATOM 3103 C C . SER A 1 418 ? -50.230 7.065 -34.544 1.00 38.12 ? 480 SER A C 1 +ATOM 3104 O O . SER A 1 418 ? -50.152 5.851 -34.333 1.00 45.13 ? 480 SER A O 1 +ATOM 3105 C CB . SER A 1 418 ? -52.473 8.128 -34.267 1.00 38.00 ? 480 SER A CB 1 +ATOM 3106 O OG . SER A 1 418 ? -53.039 6.895 -34.677 1.00 38.00 ? 480 SER A OG 1 +ATOM 3107 N N . LEU A 1 419 ? -49.537 7.663 -35.507 1.00 44.50 ? 481 LEU A N 1 +ATOM 3108 C CA . LEU A 1 419 ? -48.712 6.896 -36.426 1.00 44.71 ? 481 LEU A CA 1 +ATOM 3109 C C . LEU A 1 419 ? -47.404 6.437 -35.799 1.00 47.87 ? 481 LEU A C 1 +ATOM 3110 O O . LEU A 1 419 ? -46.690 5.637 -36.413 1.00 53.52 ? 481 LEU A O 1 +ATOM 3111 C CB . LEU A 1 419 ? -48.432 7.733 -37.678 1.00 41.04 ? 481 LEU A CB 1 +ATOM 3112 C CG . LEU A 1 419 ? -49.671 8.179 -38.466 1.00 38.00 ? 481 LEU A CG 1 +ATOM 3113 C CD1 . LEU A 1 419 ? -49.326 9.283 -39.443 1.00 41.25 ? 481 LEU A CD1 1 +ATOM 3114 C CD2 . LEU A 1 419 ? -50.328 7.019 -39.194 1.00 38.00 ? 481 LEU A CD2 1 +ATOM 3115 N N . LEU A 1 420 ? -47.067 6.913 -34.601 1.00 41.52 ? 482 LEU A N 1 +ATOM 3116 C CA . LEU A 1 420 ? -45.831 6.469 -33.974 1.00 46.92 ? 482 LEU A CA 1 +ATOM 3117 C C . LEU A 1 420 ? -45.923 5.046 -33.437 1.00 56.66 ? 482 LEU A C 1 +ATOM 3118 O O . LEU A 1 420 ? -44.883 4.394 -33.278 1.00 60.49 ? 482 LEU A O 1 +ATOM 3119 C CB . LEU A 1 420 ? -45.432 7.436 -32.862 1.00 48.60 ? 482 LEU A CB 1 +ATOM 3120 C CG . LEU A 1 420 ? -44.738 8.702 -33.362 1.00 45.16 ? 482 LEU A CG 1 +ATOM 3121 C CD1 . LEU A 1 420 ? -44.433 9.632 -32.206 1.00 49.74 ? 482 LEU A CD1 1 +ATOM 3122 C CD2 . LEU A 1 420 ? -43.471 8.338 -34.107 1.00 42.05 ? 482 LEU A CD2 1 +ATOM 3123 N N . GLU A 1 421 ? -47.139 4.538 -33.181 1.00 58.42 ? 483 GLU A N 1 +ATOM 3124 C CA . GLU A 1 421 ? -47.335 3.178 -32.670 1.00 56.57 ? 483 GLU A CA 1 +ATOM 3125 C C . GLU A 1 421 ? -47.111 2.113 -33.727 1.00 52.74 ? 483 GLU A C 1 +ATOM 3126 O O . GLU A 1 421 ? -47.331 0.930 -33.451 1.00 46.72 ? 483 GLU A O 1 +ATOM 3127 C CB . GLU A 1 421 ? -48.745 3.015 -32.088 1.00 50.95 ? 483 GLU A CB 1 +ATOM 3128 C CG . GLU A 1 421 ? -49.323 4.281 -31.462 1.00 53.97 ? 483 GLU A CG 1 +ATOM 3129 C CD . GLU A 1 421 ? -50.788 4.134 -31.049 1.00 64.57 ? 483 GLU A CD 1 +ATOM 3130 O OE1 . GLU A 1 421 ? -51.602 3.634 -31.863 1.00 53.93 ? 483 GLU A OE1 1 +ATOM 3131 O OE2 . GLU A 1 421 ? -51.129 4.530 -29.912 1.00 70.14 ? 483 GLU A OE2 1 +ATOM 3132 N N . ASP A 1 422 ? -46.688 2.497 -34.924 1.00 54.81 ? 484 ASP A N 1 +ATOM 3133 C CA . ASP A 1 422 ? -46.462 1.562 -36.012 1.00 54.80 ? 484 ASP A CA 1 +ATOM 3134 C C . ASP A 1 422 ? -44.972 1.315 -36.204 1.00 52.40 ? 484 ASP A C 1 +ATOM 3135 O O . ASP A 1 422 ? -44.145 2.204 -35.989 1.00 54.85 ? 484 ASP A O 1 +ATOM 3136 C CB . ASP A 1 422 ? -47.078 2.073 -37.308 1.00 53.10 ? 484 ASP A CB 1 +ATOM 3137 C CG . ASP A 1 422 ? -47.183 0.993 -38.351 1.00 55.03 ? 484 ASP A CG 1 +ATOM 3138 O OD1 . ASP A 1 422 ? -46.863 -0.168 -38.026 1.00 56.64 ? 484 ASP A OD1 1 +ATOM 3139 O OD2 . ASP A 1 422 ? -47.573 1.298 -39.493 1.00 61.29 ? 484 ASP A OD2 1 +ATOM 3140 N N . GLN A 1 423 ? -44.641 0.084 -36.604 1.00 52.43 ? 485 GLN A N 1 +ATOM 3141 C CA . GLN A 1 423 ? -43.249 -0.300 -36.798 1.00 53.97 ? 485 GLN A CA 1 +ATOM 3142 C C . GLN A 1 423 ? -42.587 0.495 -37.908 1.00 48.98 ? 485 GLN A C 1 +ATOM 3143 O O . GLN A 1 423 ? -41.362 0.667 -37.890 1.00 46.71 ? 485 GLN A O 1 +ATOM 3144 C CB . GLN A 1 423 ? -43.156 -1.801 -37.099 1.00 56.30 ? 485 GLN A CB 1 +ATOM 3145 C CG . GLN A 1 423 ? -41.735 -2.361 -37.160 1.00 62.58 ? 485 GLN A CG 1 +ATOM 3146 C CD . GLN A 1 423 ? -41.690 -3.873 -37.008 1.00 66.54 ? 485 GLN A CD 1 +ATOM 3147 O OE1 . GLN A 1 423 ? -42.235 -4.426 -36.050 1.00 85.03 ? 485 GLN A OE1 1 +ATOM 3148 N NE2 . GLN A 1 423 ? -41.043 -4.549 -37.957 1.00 44.53 ? 485 GLN A NE2 1 +ATOM 3149 N N . LEU A 1 424 ? -43.370 1.018 -38.849 1.00 42.40 ? 486 LEU A N 1 +ATOM 3150 C CA . LEU A 1 424 ? -42.833 1.744 -39.988 1.00 45.60 ? 486 LEU A CA 1 +ATOM 3151 C C . LEU A 1 424 ? -42.728 3.246 -39.747 1.00 52.10 ? 486 LEU A C 1 +ATOM 3152 O O . LEU A 1 424 ? -42.583 4.005 -40.713 1.00 55.13 ? 486 LEU A O 1 +ATOM 3153 C CB . LEU A 1 424 ? -43.688 1.475 -41.226 1.00 47.60 ? 486 LEU A CB 1 +ATOM 3154 C CG . LEU A 1 424 ? -43.766 0.023 -41.695 1.00 52.07 ? 486 LEU A CG 1 +ATOM 3155 C CD1 . LEU A 1 424 ? -44.403 -0.050 -43.077 1.00 50.42 ? 486 LEU A CD1 1 +ATOM 3156 C CD2 . LEU A 1 424 ? -42.376 -0.604 -41.703 1.00 55.34 ? 486 LEU A CD2 1 +ATOM 3157 N N . SER A 1 425 ? -42.758 3.688 -38.493 1.00 56.40 ? 487 SER A N 1 +ATOM 3158 C CA . SER A 1 425 ? -42.662 5.114 -38.216 1.00 50.16 ? 487 SER A CA 1 +ATOM 3159 C C . SER A 1 425 ? -41.278 5.631 -38.606 1.00 44.07 ? 487 SER A C 1 +ATOM 3160 O O . SER A 1 425 ? -40.266 4.985 -38.311 1.00 38.00 ? 487 SER A O 1 +ATOM 3161 C CB . SER A 1 425 ? -42.932 5.398 -36.738 1.00 51.10 ? 487 SER A CB 1 +ATOM 3162 O OG . SER A 1 425 ? -44.273 5.097 -36.395 1.00 49.27 ? 487 SER A OG 1 +ATOM 3163 N N . PRO A 1 426 ? -41.197 6.807 -39.252 1.00 47.66 ? 488 PRO A N 1 +ATOM 3164 C CA . PRO A 1 426 ? -42.345 7.661 -39.584 1.00 49.95 ? 488 PRO A CA 1 +ATOM 3165 C C . PRO A 1 426 ? -43.058 7.263 -40.874 1.00 43.74 ? 488 PRO A C 1 +ATOM 3166 O O . PRO A 1 426 ? -42.427 7.198 -41.928 1.00 40.22 ? 488 PRO A O 1 +ATOM 3167 C CB . PRO A 1 426 ? -41.708 9.042 -39.732 1.00 51.57 ? 488 PRO A CB 1 +ATOM 3168 C CG . PRO A 1 426 ? -40.335 8.752 -40.239 1.00 45.51 ? 488 PRO A CG 1 +ATOM 3169 C CD . PRO A 1 426 ? -39.919 7.424 -39.651 1.00 45.78 ? 488 PRO A CD 1 +ATOM 3170 N N . VAL A 1 427 ? -44.367 7.009 -40.791 1.00 41.56 ? 489 VAL A N 1 +ATOM 3171 C CA . VAL A 1 427 ? -45.095 6.584 -41.983 1.00 43.16 ? 489 VAL A CA 1 +ATOM 3172 C C . VAL A 1 427 ? -45.464 7.760 -42.880 1.00 42.46 ? 489 VAL A C 1 +ATOM 3173 O O . VAL A 1 427 ? -45.637 7.577 -44.092 1.00 42.81 ? 489 VAL A O 1 +ATOM 3174 C CB . VAL A 1 427 ? -46.352 5.780 -41.605 1.00 38.00 ? 489 VAL A CB 1 +ATOM 3175 C CG1 . VAL A 1 427 ? -45.986 4.641 -40.671 1.00 45.70 ? 489 VAL A CG1 1 +ATOM 3176 C CG2 . VAL A 1 427 ? -47.395 6.664 -40.991 1.00 38.00 ? 489 VAL A CG2 1 +ATOM 3177 N N . LEU A 1 428 ? -45.570 8.966 -42.329 1.00 40.69 ? 490 LEU A N 1 +ATOM 3178 C CA . LEU A 1 428 ? -45.847 10.165 -43.107 1.00 38.94 ? 490 LEU A CA 1 +ATOM 3179 C C . LEU A 1 428 ? -44.766 11.194 -42.820 1.00 45.61 ? 490 LEU A C 1 +ATOM 3180 O O . LEU A 1 428 ? -44.420 11.423 -41.657 1.00 39.50 ? 490 LEU A O 1 +ATOM 3181 C CB . LEU A 1 428 ? -47.224 10.744 -42.775 1.00 38.19 ? 490 LEU A CB 1 +ATOM 3182 C CG . LEU A 1 428 ? -48.440 10.013 -43.338 1.00 38.00 ? 490 LEU A CG 1 +ATOM 3183 C CD1 . LEU A 1 428 ? -49.707 10.746 -42.958 1.00 38.00 ? 490 LEU A CD1 1 +ATOM 3184 C CD2 . LEU A 1 428 ? -48.330 9.904 -44.835 1.00 38.00 ? 490 LEU A CD2 1 +ATOM 3185 N N . THR A 1 429 ? -44.227 11.797 -43.879 1.00 45.46 ? 491 THR A N 1 +ATOM 3186 C CA . THR A 1 429 ? -43.264 12.874 -43.716 1.00 40.09 ? 491 THR A CA 1 +ATOM 3187 C C . THR A 1 429 ? -43.965 14.127 -43.199 1.00 47.15 ? 491 THR A C 1 +ATOM 3188 O O . THR A 1 429 ? -45.194 14.205 -43.133 1.00 52.09 ? 491 THR A O 1 +ATOM 3189 C CB . THR A 1 429 ? -42.551 13.178 -45.033 1.00 39.19 ? 491 THR A CB 1 +ATOM 3190 O OG1 . THR A 1 429 ? -43.455 13.838 -45.926 1.00 45.19 ? 491 THR A OG1 1 +ATOM 3191 C CG2 . THR A 1 429 ? -42.041 11.907 -45.678 1.00 49.24 ? 491 THR A CG2 1 +ATOM 3192 N N . GLU A 1 430 ? -43.160 15.121 -42.835 1.00 45.90 ? 492 GLU A N 1 +ATOM 3193 C CA . GLU A 1 430 ? -43.719 16.343 -42.266 1.00 44.34 ? 492 GLU A CA 1 +ATOM 3194 C C . GLU A 1 430 ? -44.601 17.126 -43.235 1.00 44.92 ? 492 GLU A C 1 +ATOM 3195 O O . GLU A 1 430 ? -45.686 17.562 -42.811 1.00 41.08 ? 492 GLU A O 1 +ATOM 3196 C CB . GLU A 1 430 ? -42.580 17.211 -41.718 1.00 46.43 ? 492 GLU A CB 1 +ATOM 3197 C CG . GLU A 1 430 ? -42.110 16.789 -40.338 1.00 53.78 ? 492 GLU A CG 1 +ATOM 3198 C CD . GLU A 1 430 ? -43.238 16.807 -39.323 1.00 54.01 ? 492 GLU A CD 1 +ATOM 3199 O OE1 . GLU A 1 430 ? -43.970 17.816 -39.282 1.00 55.14 ? 492 GLU A OE1 1 +ATOM 3200 O OE2 . GLU A 1 430 ? -43.384 15.830 -38.554 1.00 51.50 ? 492 GLU A OE2 1 +ATOM 3201 N N . PRO A 1 431 ? -44.234 17.334 -44.508 1.00 40.11 ? 493 PRO A N 1 +ATOM 3202 C CA . PRO A 1 431 ? -45.158 18.037 -45.413 1.00 38.00 ? 493 PRO A CA 1 +ATOM 3203 C C . PRO A 1 431 ? -46.518 17.372 -45.531 1.00 40.92 ? 493 PRO A C 1 +ATOM 3204 O O . PRO A 1 431 ? -47.529 18.072 -45.668 1.00 41.70 ? 493 PRO A O 1 +ATOM 3205 C CB . PRO A 1 431 ? -44.408 18.024 -46.751 1.00 38.00 ? 493 PRO A CB 1 +ATOM 3206 C CG . PRO A 1 431 ? -42.981 17.969 -46.370 1.00 39.53 ? 493 PRO A CG 1 +ATOM 3207 C CD . PRO A 1 431 ? -42.926 17.102 -45.151 1.00 41.82 ? 493 PRO A CD 1 +ATOM 3208 N N . HIS A 1 432 ? -46.575 16.040 -45.469 1.00 47.85 ? 494 HIS A N 1 +ATOM 3209 C CA . HIS A 1 432 ? -47.858 15.351 -45.557 1.00 50.81 ? 494 HIS A CA 1 +ATOM 3210 C C . HIS A 1 432 ? -48.724 15.641 -44.337 1.00 47.57 ? 494 HIS A C 1 +ATOM 3211 O O . HIS A 1 432 ? -49.925 15.907 -44.469 1.00 45.86 ? 494 HIS A O 1 +ATOM 3212 C CB . HIS A 1 432 ? -47.636 13.844 -45.709 1.00 49.64 ? 494 HIS A CB 1 +ATOM 3213 C CG . HIS A 1 432 ? -47.145 13.428 -47.063 1.00 45.94 ? 494 HIS A CG 1 +ATOM 3214 N ND1 . HIS A 1 432 ? -45.836 13.061 -47.299 1.00 43.78 ? 494 HIS A ND1 1 +ATOM 3215 C CD2 . HIS A 1 432 ? -47.793 13.287 -48.244 1.00 38.00 ? 494 HIS A CD2 1 +ATOM 3216 C CE1 . HIS A 1 432 ? -45.695 12.730 -48.570 1.00 38.73 ? 494 HIS A CE1 1 +ATOM 3217 N NE2 . HIS A 1 432 ? -46.868 12.857 -49.164 1.00 43.56 ? 494 HIS A NE2 1 +ATOM 3218 N N . LEU A 1 433 ? -48.133 15.595 -43.141 1.00 46.64 ? 495 LEU A N 1 +ATOM 3219 C CA . LEU A 1 433 ? -48.904 15.812 -41.921 1.00 48.56 ? 495 LEU A CA 1 +ATOM 3220 C C . LEU A 1 433 ? -49.475 17.223 -41.874 1.00 50.72 ? 495 LEU A C 1 +ATOM 3221 O O . LEU A 1 433 ? -50.670 17.413 -41.617 1.00 49.28 ? 495 LEU A O 1 +ATOM 3222 C CB . LEU A 1 433 ? -48.023 15.553 -40.700 1.00 50.42 ? 495 LEU A CB 1 +ATOM 3223 C CG . LEU A 1 433 ? -47.575 14.106 -40.513 1.00 51.24 ? 495 LEU A CG 1 +ATOM 3224 C CD1 . LEU A 1 433 ? -46.478 14.015 -39.460 1.00 46.93 ? 495 LEU A CD1 1 +ATOM 3225 C CD2 . LEU A 1 433 ? -48.772 13.232 -40.147 1.00 48.39 ? 495 LEU A CD2 1 +ATOM 3226 N N . LEU A 1 434 ? -48.636 18.229 -42.140 1.00 45.61 ? 496 LEU A N 1 +ATOM 3227 C CA . LEU A 1 434 ? -49.114 19.607 -42.125 1.00 42.56 ? 496 LEU A CA 1 +ATOM 3228 C C . LEU A 1 434 ? -50.142 19.855 -43.221 1.00 43.04 ? 496 LEU A C 1 +ATOM 3229 O O . LEU A 1 434 ? -51.042 20.686 -43.049 1.00 38.78 ? 496 LEU A O 1 +ATOM 3230 C CB . LEU A 1 434 ? -47.931 20.566 -42.263 1.00 38.00 ? 496 LEU A CB 1 +ATOM 3231 C CG . LEU A 1 434 ? -46.991 20.658 -41.059 1.00 38.00 ? 496 LEU A CG 1 +ATOM 3232 C CD1 . LEU A 1 434 ? -46.111 21.884 -41.165 1.00 48.98 ? 496 LEU A CD1 1 +ATOM 3233 C CD2 . LEU A 1 434 ? -47.788 20.704 -39.767 1.00 38.69 ? 496 LEU A CD2 1 +ATOM 3234 N N . ALA A 1 435 ? -50.058 19.101 -44.322 1.00 41.02 ? 497 ALA A N 1 +ATOM 3235 C CA . ALA A 1 435 ? -51.010 19.258 -45.415 1.00 42.30 ? 497 ALA A CA 1 +ATOM 3236 C C . ALA A 1 435 ? -52.423 18.931 -44.969 1.00 46.95 ? 497 ALA A C 1 +ATOM 3237 O O . ALA A 1 435 ? -53.388 19.499 -45.491 1.00 45.34 ? 497 ALA A O 1 +ATOM 3238 C CB . ALA A 1 435 ? -50.608 18.371 -46.592 1.00 45.53 ? 497 ALA A CB 1 +ATOM 3239 N N . LEU A 1 436 ? -52.563 18.009 -44.018 1.00 48.39 ? 498 LEU A N 1 +ATOM 3240 C CA . LEU A 1 436 ? -53.883 17.686 -43.496 1.00 46.86 ? 498 LEU A CA 1 +ATOM 3241 C C . LEU A 1 436 ? -54.547 18.918 -42.905 1.00 50.91 ? 498 LEU A C 1 +ATOM 3242 O O . LEU A 1 436 ? -55.736 19.165 -43.142 1.00 48.07 ? 498 LEU A O 1 +ATOM 3243 C CB . LEU A 1 436 ? -53.757 16.599 -42.437 1.00 42.06 ? 498 LEU A CB 1 +ATOM 3244 C CG . LEU A 1 436 ? -53.142 15.314 -42.961 1.00 40.04 ? 498 LEU A CG 1 +ATOM 3245 C CD1 . LEU A 1 436 ? -52.886 14.368 -41.815 1.00 43.33 ? 498 LEU A CD1 1 +ATOM 3246 C CD2 . LEU A 1 436 ? -54.098 14.715 -43.968 1.00 42.44 ? 498 LEU A CD2 1 +ATOM 3247 N N . ASP A 1 437 ? -53.777 19.731 -42.174 1.00 48.65 ? 499 ASP A N 1 +ATOM 3248 C CA . ASP A 1 437 ? -54.331 20.937 -41.573 1.00 47.30 ? 499 ASP A CA 1 +ATOM 3249 C C . ASP A 1 437 ? -54.861 21.879 -42.641 1.00 50.84 ? 499 ASP A C 1 +ATOM 3250 O O . ASP A 1 437 ? -56.015 22.319 -42.580 1.00 49.26 ? 499 ASP A O 1 +ATOM 3251 C CB . ASP A 1 437 ? -53.269 21.637 -40.726 1.00 44.89 ? 499 ASP A CB 1 +ATOM 3252 C CG . ASP A 1 437 ? -52.964 20.898 -39.441 1.00 48.63 ? 499 ASP A CG 1 +ATOM 3253 O OD1 . ASP A 1 437 ? -53.848 20.171 -38.943 1.00 49.44 ? 499 ASP A OD1 1 +ATOM 3254 O OD2 . ASP A 1 437 ? -51.839 21.059 -38.924 1.00 49.77 ? 499 ASP A OD2 1 +ATOM 3255 N N . ARG A 1 438 ? -54.033 22.173 -43.648 1.00 52.74 ? 500 ARG A N 1 +ATOM 3256 C CA . ARG A 1 438 ? -54.440 23.084 -44.713 1.00 51.82 ? 500 ARG A CA 1 +ATOM 3257 C C . ARG A 1 438 ? -55.641 22.541 -45.475 1.00 50.29 ? 500 ARG A C 1 +ATOM 3258 O O . ARG A 1 438 ? -56.581 23.286 -45.784 1.00 45.37 ? 500 ARG A O 1 +ATOM 3259 C CB . ARG A 1 438 ? -53.267 23.324 -45.659 1.00 46.03 ? 500 ARG A CB 1 +ATOM 3260 C CG . ARG A 1 438 ? -53.656 23.992 -46.954 1.00 47.96 ? 500 ARG A CG 1 +ATOM 3261 C CD . ARG A 1 438 ? -52.501 23.976 -47.922 1.00 49.17 ? 500 ARG A CD 1 +ATOM 3262 N NE . ARG A 1 438 ? -51.847 22.672 -47.948 1.00 51.77 ? 500 ARG A NE 1 +ATOM 3263 C CZ . ARG A 1 438 ? -51.019 22.275 -48.908 1.00 56.08 ? 500 ARG A CZ 1 +ATOM 3264 N NH1 . ARG A 1 438 ? -50.753 23.081 -49.926 1.00 73.29 ? 500 ARG A NH1 1 +ATOM 3265 N NH2 . ARG A 1 438 ? -50.463 21.072 -48.855 1.00 53.43 ? 500 ARG A NH2 1 +ATOM 3266 N N . ARG A 1 439 ? -55.620 21.243 -45.798 1.00 51.32 ? 501 ARG A N 1 +ATOM 3267 C CA . ARG A 1 439 ? -56.760 20.632 -46.470 1.00 51.62 ? 501 ARG A CA 1 +ATOM 3268 C C . ARG A 1 439 ? -57.991 20.624 -45.578 1.00 47.26 ? 501 ARG A C 1 +ATOM 3269 O O . ARG A 1 439 ? -59.117 20.638 -46.084 1.00 40.55 ? 501 ARG A O 1 +ATOM 3270 C CB . ARG A 1 439 ? -56.418 19.211 -46.923 1.00 49.92 ? 501 ARG A CB 1 +ATOM 3271 C CG . ARG A 1 439 ? -55.239 19.137 -47.894 1.00 52.12 ? 501 ARG A CG 1 +ATOM 3272 C CD . ARG A 1 439 ? -55.185 17.800 -48.626 1.00 52.12 ? 501 ARG A CD 1 +ATOM 3273 N NE . ARG A 1 439 ? -53.975 17.650 -49.431 1.00 49.55 ? 501 ARG A NE 1 +ATOM 3274 C CZ . ARG A 1 439 ? -53.000 16.789 -49.166 1.00 47.36 ? 501 ARG A CZ 1 +ATOM 3275 N NH1 . ARG A 1 439 ? -53.099 15.981 -48.121 1.00 48.76 ? 501 ARG A NH1 1 +ATOM 3276 N NH2 . ARG A 1 439 ? -51.936 16.722 -49.957 1.00 44.24 ? 501 ARG A NH2 1 +ATOM 3277 N N . LEU A 1 440 ? -57.796 20.599 -44.256 1.00 47.94 ? 502 LEU A N 1 +ATOM 3278 C CA . LEU A 1 440 ? -58.926 20.692 -43.337 1.00 46.68 ? 502 LEU A CA 1 +ATOM 3279 C C . LEU A 1 440 ? -59.576 22.067 -43.399 1.00 47.10 ? 502 LEU A C 1 +ATOM 3280 O O . LEU A 1 440 ? -60.808 22.180 -43.393 1.00 43.14 ? 502 LEU A O 1 +ATOM 3281 C CB . LEU A 1 440 ? -58.467 20.373 -41.915 1.00 42.26 ? 502 LEU A CB 1 +ATOM 3282 C CG . LEU A 1 440 ? -59.516 20.493 -40.811 1.00 46.11 ? 502 LEU A CG 1 +ATOM 3283 C CD1 . LEU A 1 440 ? -60.592 19.435 -40.964 1.00 38.92 ? 502 LEU A CD1 1 +ATOM 3284 C CD2 . LEU A 1 440 ? -58.836 20.377 -39.460 1.00 47.64 ? 502 LEU A CD2 1 +ATOM 3285 N N . GLN A 1 441 ? -58.764 23.124 -43.473 1.00 47.52 ? 503 GLN A N 1 +ATOM 3286 C CA . GLN A 1 441 ? -59.315 24.465 -43.606 1.00 42.05 ? 503 GLN A CA 1 +ATOM 3287 C C . GLN A 1 441 ? -60.148 24.577 -44.871 1.00 41.07 ? 503 GLN A C 1 +ATOM 3288 O O . GLN A 1 441 ? -61.261 25.114 -44.847 1.00 39.15 ? 503 GLN A O 1 +ATOM 3289 C CB . GLN A 1 441 ? -58.182 25.489 -43.615 1.00 39.14 ? 503 GLN A CB 1 +ATOM 3290 C CG . GLN A 1 441 ? -57.462 25.616 -42.286 1.00 46.96 ? 503 GLN A CG 1 +ATOM 3291 C CD . GLN A 1 441 ? -58.348 26.168 -41.185 1.00 51.66 ? 503 GLN A CD 1 +ATOM 3292 O OE1 . GLN A 1 441 ? -59.024 27.180 -41.365 1.00 63.37 ? 503 GLN A OE1 1 +ATOM 3293 N NE2 . GLN A 1 441 ? -58.345 25.504 -40.033 1.00 45.05 ? 503 GLN A NE2 1 +ATOM 3294 N N . THR A 1 442 ? -59.640 24.029 -45.976 1.00 40.11 ? 504 THR A N 1 +ATOM 3295 C CA . THR A 1 442 ? -60.355 24.093 -47.245 1.00 42.00 ? 504 THR A CA 1 +ATOM 3296 C C . THR A 1 442 ? -61.715 23.414 -47.152 1.00 43.13 ? 504 THR A C 1 +ATOM 3297 O O . THR A 1 442 ? -62.681 23.853 -47.787 1.00 40.91 ? 504 THR A O 1 +ATOM 3298 C CB . THR A 1 442 ? -59.505 23.458 -48.342 1.00 44.80 ? 504 THR A CB 1 +ATOM 3299 O OG1 . THR A 1 442 ? -58.239 24.127 -48.398 1.00 40.33 ? 504 THR A OG1 1 +ATOM 3300 C CG2 . THR A 1 442 ? -60.203 23.570 -49.691 1.00 42.61 ? 504 THR A CG2 1 +ATOM 3301 N N . ILE A 1 443 ? -61.812 22.342 -46.367 1.00 46.07 ? 505 ILE A N 1 +ATOM 3302 C CA . ILE A 1 443 ? -63.102 21.689 -46.170 1.00 45.58 ? 505 ILE A CA 1 +ATOM 3303 C C . ILE A 1 443 ? -64.022 22.585 -45.357 1.00 47.70 ? 505 ILE A C 1 +ATOM 3304 O O . ILE A 1 443 ? -65.195 22.780 -45.701 1.00 45.40 ? 505 ILE A O 1 +ATOM 3305 C CB . ILE A 1 443 ? -62.916 20.324 -45.490 1.00 38.32 ? 505 ILE A CB 1 +ATOM 3306 C CG1 . ILE A 1 443 ? -61.942 19.465 -46.280 1.00 40.15 ? 505 ILE A CG1 1 +ATOM 3307 C CG2 . ILE A 1 443 ? -64.247 19.613 -45.378 1.00 38.72 ? 505 ILE A CG2 1 +ATOM 3308 C CD1 . ILE A 1 443 ? -61.517 18.242 -45.537 1.00 43.74 ? 505 ILE A CD1 1 +ATOM 3309 N N . LEU A 1 444 ? -63.498 23.146 -44.266 1.00 46.67 ? 506 LEU A N 1 +ATOM 3310 C CA . LEU A 1 444 ? -64.299 24.028 -43.428 1.00 45.22 ? 506 LEU A CA 1 +ATOM 3311 C C . LEU A 1 444 ? -64.685 25.288 -44.182 1.00 52.00 ? 506 LEU A C 1 +ATOM 3312 O O . LEU A 1 444 ? -65.841 25.722 -44.126 1.00 52.45 ? 506 LEU A O 1 +ATOM 3313 C CB . LEU A 1 444 ? -63.524 24.377 -42.162 1.00 44.37 ? 506 LEU A CB 1 +ATOM 3314 C CG . LEU A 1 444 ? -63.307 23.193 -41.227 1.00 43.46 ? 506 LEU A CG 1 +ATOM 3315 C CD1 . LEU A 1 444 ? -62.365 23.568 -40.102 1.00 41.74 ? 506 LEU A CD1 1 +ATOM 3316 C CD2 . LEU A 1 444 ? -64.656 22.745 -40.685 1.00 41.17 ? 506 LEU A CD2 1 +ATOM 3317 N N . ARG A 1 445 ? -63.740 25.859 -44.932 1.00 53.66 ? 507 ARG A N 1 +ATOM 3318 C CA . ARG A 1 445 ? -64.047 27.047 -45.715 1.00 48.17 ? 507 ARG A CA 1 +ATOM 3319 C C . ARG A 1 445 ? -65.147 26.777 -46.730 1.00 46.18 ? 507 ARG A C 1 +ATOM 3320 O O . ARG A 1 445 ? -66.020 27.628 -46.931 1.00 44.56 ? 507 ARG A O 1 +ATOM 3321 C CB . ARG A 1 445 ? -62.778 27.543 -46.405 1.00 38.00 ? 507 ARG A CB 1 +ATOM 3322 C CG . ARG A 1 445 ? -63.007 28.714 -47.313 1.00 44.74 ? 507 ARG A CG 1 +ATOM 3323 C CD . ARG A 1 445 ? -61.710 29.399 -47.713 1.00 61.99 ? 507 ARG A CD 1 +ATOM 3324 N NE . ARG A 1 445 ? -60.672 28.480 -48.178 1.00 58.83 ? 507 ARG A NE 1 +ATOM 3325 C CZ . ARG A 1 445 ? -59.611 28.130 -47.458 1.00 51.63 ? 507 ARG A CZ 1 +ATOM 3326 N NH1 . ARG A 1 445 ? -59.450 28.621 -46.235 1.00 45.00 ? 507 ARG A NH1 1 +ATOM 3327 N NH2 . ARG A 1 445 ? -58.709 27.294 -47.959 1.00 47.26 ? 507 ARG A NH2 1 +ATOM 3328 N N . THR A 1 446 ? -65.175 25.576 -47.313 1.00 45.05 ? 508 THR A N 1 +ATOM 3329 C CA . THR A 1 446 ? -66.235 25.253 -48.262 1.00 47.47 ? 508 THR A CA 1 +ATOM 3330 C C . THR A 1 446 ? -67.579 25.127 -47.557 1.00 53.32 ? 508 THR A C 1 +ATOM 3331 O O . THR A 1 446 ? -68.611 25.529 -48.107 1.00 60.11 ? 508 THR A O 1 +ATOM 3332 C CB . THR A 1 446 ? -65.912 23.965 -49.028 1.00 41.44 ? 508 THR A CB 1 +ATOM 3333 O OG1 . THR A 1 446 ? -64.663 24.100 -49.713 1.00 38.00 ? 508 THR A OG1 1 +ATOM 3334 C CG2 . THR A 1 446 ? -66.993 23.682 -50.055 1.00 43.50 ? 508 THR A CG2 1 +ATOM 3335 N N . VAL A 1 447 ? -67.594 24.563 -46.346 1.00 46.91 ? 509 VAL A N 1 +ATOM 3336 C CA . VAL A 1 447 ? -68.853 24.424 -45.613 1.00 54.36 ? 509 VAL A CA 1 +ATOM 3337 C C . VAL A 1 447 ? -69.429 25.795 -45.285 1.00 64.86 ? 509 VAL A C 1 +ATOM 3338 O O . VAL A 1 447 ? -70.565 26.118 -45.655 1.00 64.10 ? 509 VAL A O 1 +ATOM 3339 C CB . VAL A 1 447 ? -68.652 23.582 -44.343 1.00 44.52 ? 509 VAL A CB 1 +ATOM 3340 C CG1 . VAL A 1 447 ? -69.954 23.509 -43.552 1.00 38.00 ? 509 VAL A CG1 1 +ATOM 3341 C CG2 . VAL A 1 447 ? -68.169 22.201 -44.708 1.00 45.36 ? 509 VAL A CG2 1 +ATOM 3342 N N . GLU A 1 448 ? -68.644 26.630 -44.597 1.00 69.56 ? 510 GLU A N 1 +ATOM 3343 C CA . GLU A 1 448 ? -69.110 27.975 -44.280 1.00 67.43 ? 510 GLU A CA 1 +ATOM 3344 C C . GLU A 1 448 ? -69.261 28.806 -45.541 1.00 63.32 ? 510 GLU A C 1 +ATOM 3345 O O . GLU A 1 448 ? -70.110 29.702 -45.593 1.00 62.32 ? 510 GLU A O 1 +ATOM 3346 C CB . GLU A 1 448 ? -68.157 28.651 -43.286 1.00 68.08 ? 510 GLU A CB 1 +ATOM 3347 C CG . GLU A 1 448 ? -66.903 29.288 -43.897 1.00 69.12 ? 510 GLU A CG 1 +ATOM 3348 C CD . GLU A 1 448 ? -66.014 29.958 -42.851 1.00 77.48 ? 510 GLU A CD 1 +ATOM 3349 O OE1 . GLU A 1 448 ? -66.551 30.399 -41.812 1.00 78.13 ? 510 GLU A OE1 1 +ATOM 3350 O OE2 . GLU A 1 448 ? -64.782 30.044 -43.067 1.00 67.67 ? 510 GLU A OE2 1 +ATOM 3351 N N . GLY A 1 449 ? -68.495 28.484 -46.583 1.00 59.86 ? 511 GLY A N 1 +ATOM 3352 C CA . GLY A 1 449 ? -68.584 29.257 -47.807 1.00 70.51 ? 511 GLY A CA 1 +ATOM 3353 C C . GLY A 1 449 ? -69.928 29.090 -48.487 1.00 78.81 ? 511 GLY A C 1 +ATOM 3354 O O . GLY A 1 449 ? -70.586 30.073 -48.831 1.00 86.91 ? 511 GLY A O 1 +ATOM 3355 N N . CYS A 1 450 ? -70.365 27.846 -48.669 1.00 74.95 ? 512 CYS A N 1 +ATOM 3356 C CA . CYS A 1 450 ? -71.648 27.588 -49.306 1.00 78.00 ? 512 CYS A CA 1 +ATOM 3357 C C . CYS A 1 450 ? -72.809 27.577 -48.314 1.00 67.90 ? 512 CYS A C 1 +ATOM 3358 O O . CYS A 1 450 ? -73.956 27.369 -48.726 1.00 69.17 ? 512 CYS A O 1 +ATOM 3359 C CB . CYS A 1 450 ? -71.580 26.284 -50.116 1.00 83.17 ? 512 CYS A CB 1 +ATOM 3360 S SG . CYS A 1 450 ? -71.857 24.755 -49.221 1.00 80.23 ? 512 CYS A SG 1 +ATOM 3361 N N . ILE A 1 451 ? -72.544 27.823 -47.028 1.00 65.21 ? 513 ILE A N 1 +ATOM 3362 C CA . ILE A 1 451 ? -73.629 28.106 -46.090 1.00 69.75 ? 513 ILE A CA 1 +ATOM 3363 C C . ILE A 1 451 ? -74.290 29.437 -46.431 1.00 67.31 ? 513 ILE A C 1 +ATOM 3364 O O . ILE A 1 451 ? -75.509 29.595 -46.302 1.00 58.86 ? 513 ILE A O 1 +ATOM 3365 C CB . ILE A 1 451 ? -73.106 28.092 -44.640 1.00 64.73 ? 513 ILE A CB 1 +ATOM 3366 C CG1 . ILE A 1 451 ? -73.278 26.708 -44.018 1.00 68.11 ? 513 ILE A CG1 1 +ATOM 3367 C CG2 . ILE A 1 451 ? -73.825 29.127 -43.789 1.00 66.02 ? 513 ILE A CG2 1 +ATOM 3368 C CD1 . ILE A 1 451 ? -73.034 26.687 -42.534 1.00 53.52 ? 513 ILE A CD1 1 +ATOM 3369 N N . VAL A 1 452 ? -73.497 30.408 -46.893 1.00 65.63 ? 514 VAL A N 1 +ATOM 3370 C CA . VAL A 1 452 ? -74.014 31.729 -47.229 1.00 56.01 ? 514 VAL A CA 1 +ATOM 3371 C C . VAL A 1 452 ? -75.023 31.663 -48.362 1.00 62.79 ? 514 VAL A C 1 +ATOM 3372 O O . VAL A 1 452 ? -75.884 32.546 -48.482 1.00 67.73 ? 514 VAL A O 1 +ATOM 3373 C CB . VAL A 1 452 ? -72.865 32.679 -47.611 1.00 47.95 ? 514 VAL A CB 1 +ATOM 3374 C CG1 . VAL A 1 452 ? -71.694 32.533 -46.661 1.00 47.54 ? 514 VAL A CG1 1 +ATOM 3375 C CG2 . VAL A 1 452 ? -72.426 32.467 -49.064 1.00 52.58 ? 514 VAL A CG2 1 +ATOM 3376 N N . ALA A 1 453 ? -74.964 30.616 -49.181 1.00 64.31 ? 515 ALA A N 1 +ATOM 3377 C CA . ALA A 1 453 ? -75.849 30.461 -50.328 1.00 62.92 ? 515 ALA A CA 1 +ATOM 3378 C C . ALA A 1 453 ? -77.064 29.593 -50.035 1.00 69.44 ? 515 ALA A C 1 +ATOM 3379 O O . ALA A 1 453 ? -77.999 29.578 -50.840 1.00 78.15 ? 515 ALA A O 1 +ATOM 3380 C CB . ALA A 1 453 ? -75.069 29.880 -51.512 1.00 54.90 ? 515 ALA A CB 1 +ATOM 3381 N N . HIS A 1 454 ? -77.061 28.844 -48.931 1.00 65.25 ? 516 HIS A N 1 +ATOM 3382 C CA . HIS A 1 454 ? -78.189 27.983 -48.600 1.00 67.27 ? 516 HIS A CA 1 +ATOM 3383 C C . HIS A 1 454 ? -78.629 28.049 -47.140 1.00 76.50 ? 516 HIS A C 1 +ATOM 3384 O O . HIS A 1 454 ? -79.726 27.563 -46.831 1.00 71.57 ? 516 HIS A O 1 +ATOM 3385 C CB . HIS A 1 454 ? -77.873 26.521 -48.952 1.00 69.17 ? 516 HIS A CB 1 +ATOM 3386 C CG . HIS A 1 454 ? -77.457 26.310 -50.376 1.00 70.76 ? 516 HIS A CG 1 +ATOM 3387 N ND1 . HIS A 1 454 ? -76.255 26.764 -50.876 1.00 73.24 ? 516 HIS A ND1 1 +ATOM 3388 C CD2 . HIS A 1 454 ? -78.075 25.678 -51.402 1.00 73.95 ? 516 HIS A CD2 1 +ATOM 3389 C CE1 . HIS A 1 454 ? -76.151 26.425 -52.148 1.00 70.00 ? 516 HIS A CE1 1 +ATOM 3390 N NE2 . HIS A 1 454 ? -77.243 25.766 -52.493 1.00 75.66 ? 516 HIS A NE2 1 +ATOM 3391 N N . GLY A 1 455 ? -77.828 28.612 -46.240 1.00 77.43 ? 517 GLY A N 1 +ATOM 3392 C CA . GLY A 1 455 ? -78.151 28.654 -44.827 1.00 75.86 ? 517 GLY A CA 1 +ATOM 3393 C C . GLY A 1 455 ? -77.932 27.315 -44.140 1.00 76.87 ? 517 GLY A C 1 +ATOM 3394 O O . GLY A 1 455 ? -77.791 26.270 -44.770 1.00 78.60 ? 517 GLY A O 1 +ATOM 3395 N N . GLN A 1 456 ? -77.908 27.356 -42.806 1.00 72.30 ? 518 GLN A N 1 +ATOM 3396 C CA . GLN A 1 456 ? -77.724 26.137 -42.020 1.00 66.97 ? 518 GLN A CA 1 +ATOM 3397 C C . GLN A 1 456 ? -78.903 25.166 -42.127 1.00 71.13 ? 518 GLN A C 1 +ATOM 3398 O O . GLN A 1 456 ? -78.827 24.064 -41.569 1.00 66.28 ? 518 GLN A O 1 +ATOM 3399 C CB . GLN A 1 456 ? -77.469 26.502 -40.557 1.00 64.91 ? 518 GLN A CB 1 +ATOM 3400 C CG . GLN A 1 456 ? -76.153 27.242 -40.313 1.00 63.15 ? 518 GLN A CG 1 +ATOM 3401 C CD . GLN A 1 456 ? -75.818 27.364 -38.832 1.00 67.23 ? 518 GLN A CD 1 +ATOM 3402 O OE1 . GLN A 1 456 ? -76.424 26.698 -37.991 1.00 71.00 ? 518 GLN A OE1 1 +ATOM 3403 N NE2 . GLN A 1 456 ? -74.851 28.220 -38.508 1.00 54.77 ? 518 GLN A NE2 1 +ATOM 3404 N N . GLN A 1 457 ? -79.972 25.540 -42.835 1.00 78.19 ? 519 GLN A N 1 +ATOM 3405 C CA . GLN A 1 457 ? -81.095 24.631 -43.050 1.00 77.20 ? 519 GLN A CA 1 +ATOM 3406 C C . GLN A 1 457 ? -80.680 23.443 -43.911 1.00 78.81 ? 519 GLN A C 1 +ATOM 3407 O O . GLN A 1 457 ? -80.860 22.285 -43.518 1.00 76.22 ? 519 GLN A O 1 +ATOM 3408 C CB . GLN A 1 457 ? -82.262 25.387 -43.696 1.00 87.99 ? 519 GLN A CB 1 +ATOM 3409 C CG . GLN A 1 457 ? -83.305 24.497 -44.384 1.00 99.70 ? 519 GLN A CG 1 +ATOM 3410 C CD . GLN A 1 457 ? -83.631 24.947 -45.808 1.00 98.98 ? 519 GLN A CD 1 +ATOM 3411 O OE1 . GLN A 1 457 ? -82.741 25.065 -46.658 1.00 96.93 ? 519 GLN A OE1 1 +ATOM 3412 N NE2 . GLN A 1 457 ? -84.912 25.196 -46.072 1.00 90.38 ? 519 GLN A NE2 1 +ATOM 3413 N N . SER A 1 458 ? -80.118 23.716 -45.089 1.00 75.63 ? 520 SER A N 1 +ATOM 3414 C CA . SER A 1 458 ? -79.823 22.695 -46.082 1.00 69.39 ? 520 SER A CA 1 +ATOM 3415 C C . SER A 1 458 ? -78.347 22.329 -46.154 1.00 70.36 ? 520 SER A C 1 +ATOM 3416 O O . SER A 1 458 ? -77.967 21.534 -47.018 1.00 78.60 ? 520 SER A O 1 +ATOM 3417 C CB . SER A 1 458 ? -80.298 23.159 -47.465 1.00 69.89 ? 520 SER A CB 1 +ATOM 3418 O OG . SER A 1 458 ? -79.992 22.206 -48.468 1.00 77.00 ? 520 SER A OG 1 +ATOM 3419 N N . VAL A 1 459 ? -77.502 22.879 -45.284 1.00 57.82 ? 521 VAL A N 1 +ATOM 3420 C CA . VAL A 1 459 ? -76.091 22.514 -45.267 1.00 56.19 ? 521 VAL A CA 1 +ATOM 3421 C C . VAL A 1 459 ? -75.707 21.729 -44.020 1.00 61.38 ? 521 VAL A C 1 +ATOM 3422 O O . VAL A 1 459 ? -74.589 21.195 -43.956 1.00 64.35 ? 521 VAL A O 1 +ATOM 3423 C CB . VAL A 1 459 ? -75.195 23.756 -45.433 1.00 54.21 ? 521 VAL A CB 1 +ATOM 3424 C CG1 . VAL A 1 459 ? -73.806 23.368 -45.909 1.00 54.69 ? 521 VAL A CG1 1 +ATOM 3425 C CG2 . VAL A 1 459 ? -75.809 24.710 -46.433 1.00 56.63 ? 521 VAL A CG2 1 +ATOM 3426 N N . ILE A 1 460 ? -76.618 21.573 -43.060 1.00 67.30 ? 522 ILE A N 1 +ATOM 3427 C CA . ILE A 1 460 ? -76.377 20.768 -41.865 1.00 60.48 ? 522 ILE A CA 1 +ATOM 3428 C C . ILE A 1 460 ? -77.567 19.839 -41.678 1.00 66.36 ? 522 ILE A C 1 +ATOM 3429 O O . ILE A 1 460 ? -78.707 20.301 -41.529 1.00 68.19 ? 522 ILE A O 1 +ATOM 3430 C CB . ILE A 1 460 ? -76.157 21.632 -40.611 1.00 46.27 ? 522 ILE A CB 1 +ATOM 3431 C CG1 . ILE A 1 460 ? -74.680 21.984 -40.456 1.00 38.00 ? 522 ILE A CG1 1 +ATOM 3432 C CG2 . ILE A 1 460 ? -76.641 20.922 -39.366 1.00 56.16 ? 522 ILE A CG2 1 +ATOM 3433 C CD1 . ILE A 1 460 ? -74.258 23.172 -41.253 1.00 41.30 ? 522 ILE A CD1 1 +ATOM 3434 N N . VAL A 1 461 ? -77.298 18.541 -41.653 1.00 64.07 ? 523 VAL A N 1 +ATOM 3435 C CA . VAL A 1 461 ? -78.331 17.511 -41.580 1.00 66.57 ? 523 VAL A CA 1 +ATOM 3436 C C . VAL A 1 461 ? -78.110 16.761 -40.273 1.00 69.20 ? 523 VAL A C 1 +ATOM 3437 O O . VAL A 1 461 ? -77.370 15.775 -40.207 1.00 64.28 ? 523 VAL A O 1 +ATOM 3438 C CB . VAL A 1 461 ? -78.297 16.570 -42.785 1.00 71.04 ? 523 VAL A CB 1 +ATOM 3439 C CG1 . VAL A 1 461 ? -79.213 17.081 -43.889 1.00 65.26 ? 523 VAL A CG1 1 +ATOM 3440 C CG2 . VAL A 1 461 ? -76.876 16.454 -43.301 1.00 67.46 ? 523 VAL A CG2 1 +ATOM 3441 N N . ASP A 1 462 ? -78.735 17.253 -39.207 1.00 78.80 ? 524 ASP A N 1 +ATOM 3442 C CA . ASP A 1 462 ? -78.574 16.674 -37.879 1.00 84.44 ? 524 ASP A CA 1 +ATOM 3443 C C . ASP A 1 462 ? -79.494 15.476 -37.669 1.00 90.68 ? 524 ASP A C 1 +ATOM 3444 O O . ASP A 1 462 ? -80.162 15.381 -36.636 1.00 99.67 ? 524 ASP A O 1 +ATOM 3445 C CB . ASP A 1 462 ? -78.826 17.741 -36.812 1.00 80.89 ? 524 ASP A CB 1 +ATOM 3446 C CG . ASP A 1 462 ? -80.144 18.469 -37.016 1.00 99.45 ? 524 ASP A CG 1 +ATOM 3447 O OD1 . ASP A 1 462 ? -80.579 18.603 -38.181 1.00 94.96 ? 524 ASP A OD1 1 +ATOM 3448 O OD2 . ASP A 1 462 ? -80.744 18.906 -36.008 1.00 110.04 ? 524 ASP A OD2 1 +ATOM 3449 N N . GLY A 1 463 ? -79.544 14.563 -38.639 1.00 81.03 ? 525 GLY A N 1 +ATOM 3450 C CA . GLY A 1 463 ? -80.300 13.343 -38.482 1.00 83.46 ? 525 GLY A CA 1 +ATOM 3451 C C . GLY A 1 463 ? -79.760 12.498 -37.344 1.00 96.62 ? 525 GLY A C 1 +ATOM 3452 O O . GLY A 1 463 ? -78.587 12.605 -36.967 1.00 103.85 ? 525 GLY A O 1 +ATOM 3453 N N . PRO A 1 464 ? -80.608 11.627 -36.773 1.00 104.91 ? 526 PRO A N 1 +ATOM 3454 C CA . PRO A 1 464 ? -80.200 10.824 -35.611 1.00 104.35 ? 526 PRO A CA 1 +ATOM 3455 C C . PRO A 1 464 ? -79.246 9.682 -35.969 1.00 105.24 ? 526 PRO A C 1 +ATOM 3456 O O . PRO A 1 464 ? -78.917 9.497 -37.144 1.00 101.73 ? 526 PRO A O 1 +ATOM 3457 C CB . PRO A 1 464 ? -81.530 10.279 -35.080 1.00 91.92 ? 526 PRO A CB 1 +ATOM 3458 C CG . PRO A 1 464 ? -82.412 10.222 -36.281 1.00 91.45 ? 526 PRO A CG 1 +ATOM 3459 C CD . PRO A 1 464 ? -82.010 11.380 -37.158 1.00 93.39 ? 526 PRO A CD 1 +ATOM 3460 N N . SER B 2 134 ? -5.555 22.103 -75.953 1.00 70.85 ? 134 SER C N 1 +ATOM 3461 C CA . SER B 2 134 ? -4.121 21.850 -75.885 1.00 74.77 ? 134 SER C CA 1 +ATOM 3462 C C . SER B 2 134 ? -3.849 20.353 -75.765 1.00 85.14 ? 134 SER C C 1 +ATOM 3463 O O . SER B 2 134 ? -3.062 19.796 -76.530 1.00 79.35 ? 134 SER C O 1 +ATOM 3464 C CB . SER B 2 134 ? -3.492 22.603 -74.707 1.00 76.97 ? 134 SER C CB 1 +ATOM 3465 O OG . SER B 2 134 ? -3.908 22.055 -73.466 1.00 78.94 ? 134 SER C OG 1 +ATOM 3466 N N . VAL B 2 135 ? -4.510 19.712 -74.797 1.00 88.32 ? 135 VAL C N 1 +ATOM 3467 C CA . VAL B 2 135 ? -4.308 18.282 -74.566 1.00 85.66 ? 135 VAL C CA 1 +ATOM 3468 C C . VAL B 2 135 ? -4.707 17.486 -75.801 1.00 86.60 ? 135 VAL C C 1 +ATOM 3469 O O . VAL B 2 135 ? -3.946 16.645 -76.296 1.00 78.30 ? 135 VAL C O 1 +ATOM 3470 C CB . VAL B 2 135 ? -5.098 17.823 -73.327 1.00 80.98 ? 135 VAL C CB 1 +ATOM 3471 C CG1 . VAL B 2 135 ? -4.535 16.515 -72.797 1.00 77.06 ? 135 VAL C CG1 1 +ATOM 3472 C CG2 . VAL B 2 135 ? -5.082 18.902 -72.257 1.00 83.50 ? 135 VAL C CG2 1 +ATOM 3473 N N . LEU B 2 136 ? -5.911 17.750 -76.317 1.00 83.95 ? 136 LEU C N 1 +ATOM 3474 C CA . LEU B 2 136 ? -6.370 17.079 -77.527 1.00 79.86 ? 136 LEU C CA 1 +ATOM 3475 C C . LEU B 2 136 ? -5.490 17.441 -78.714 1.00 79.96 ? 136 LEU C C 1 +ATOM 3476 O O . LEU B 2 136 ? -5.167 16.583 -79.546 1.00 73.03 ? 136 LEU C O 1 +ATOM 3477 C CB . LEU B 2 136 ? -7.826 17.452 -77.797 1.00 81.46 ? 136 LEU C CB 1 +ATOM 3478 C CG . LEU B 2 136 ? -8.611 16.496 -78.690 1.00 81.39 ? 136 LEU C CG 1 +ATOM 3479 C CD1 . LEU B 2 136 ? -8.386 15.069 -78.231 1.00 72.54 ? 136 LEU C CD1 1 +ATOM 3480 C CD2 . LEU B 2 136 ? -10.096 16.844 -78.686 1.00 81.76 ? 136 LEU C CD2 1 +ATOM 3481 N N . GLN B 2 137 ? -5.102 18.713 -78.812 1.00 78.74 ? 137 GLN C N 1 +ATOM 3482 C CA . GLN B 2 137 ? -4.166 19.129 -79.848 1.00 81.85 ? 137 GLN C CA 1 +ATOM 3483 C C . GLN B 2 137 ? -2.866 18.340 -79.753 1.00 85.22 ? 137 GLN C C 1 +ATOM 3484 O O . GLN B 2 137 ? -2.304 17.927 -80.775 1.00 78.93 ? 137 GLN C O 1 +ATOM 3485 C CB . GLN B 2 137 ? -3.905 20.630 -79.731 1.00 82.87 ? 137 GLN C CB 1 +ATOM 3486 C CG . GLN B 2 137 ? -3.109 21.219 -80.878 1.00 92.59 ? 137 GLN C CG 1 +ATOM 3487 C CD . GLN B 2 137 ? -3.846 21.123 -82.198 1.00 98.20 ? 137 GLN C CD 1 +ATOM 3488 O OE1 . GLN B 2 137 ? -5.052 21.367 -82.264 1.00 100.61 ? 137 GLN C OE1 1 +ATOM 3489 N NE2 . GLN B 2 137 ? -3.122 20.783 -83.261 1.00 86.75 ? 137 GLN C NE2 1 +ATOM 3490 N N . SER B 2 138 ? -2.378 18.113 -78.528 1.00 90.62 ? 138 SER C N 1 +ATOM 3491 C CA . SER B 2 138 ? -1.123 17.387 -78.341 1.00 88.57 ? 138 SER C CA 1 +ATOM 3492 C C . SER B 2 138 ? -1.299 15.896 -78.588 1.00 84.29 ? 138 SER C C 1 +ATOM 3493 O O . SER B 2 138 ? -0.384 15.237 -79.096 1.00 76.24 ? 138 SER C O 1 +ATOM 3494 C CB . SER B 2 138 ? -0.579 17.612 -76.930 1.00 84.47 ? 138 SER C CB 1 +ATOM 3495 O OG . SER B 2 138 ? -0.424 18.989 -76.644 1.00 100.09 ? 138 SER C OG 1 +ATOM 3496 N N . LEU B 2 139 ? -2.460 15.345 -78.217 1.00 83.51 ? 139 LEU C N 1 +ATOM 3497 C CA . LEU B 2 139 ? -2.689 13.915 -78.395 1.00 83.46 ? 139 LEU C CA 1 +ATOM 3498 C C . LEU B 2 139 ? -2.560 13.523 -79.859 1.00 77.50 ? 139 LEU C C 1 +ATOM 3499 O O . LEU B 2 139 ? -1.792 12.620 -80.208 1.00 69.53 ? 139 LEU C O 1 +ATOM 3500 C CB . LEU B 2 139 ? -4.068 13.521 -77.866 1.00 87.74 ? 139 LEU C CB 1 +ATOM 3501 C CG . LEU B 2 139 ? -4.373 12.036 -78.116 1.00 86.53 ? 139 LEU C CG 1 +ATOM 3502 C CD1 . LEU B 2 139 ? -3.550 11.141 -77.187 1.00 77.56 ? 139 LEU C CD1 1 +ATOM 3503 C CD2 . LEU B 2 139 ? -5.868 11.716 -78.026 1.00 79.08 ? 139 LEU C CD2 1 +ATOM 3504 N N . PHE B 2 140 ? -3.298 14.207 -80.735 1.00 77.84 ? 140 PHE C N 1 +ATOM 3505 C CA . PHE B 2 140 ? -3.184 13.933 -82.159 1.00 74.98 ? 140 PHE C CA 1 +ATOM 3506 C C . PHE B 2 140 ? -1.818 14.331 -82.701 1.00 75.13 ? 140 PHE C C 1 +ATOM 3507 O O . PHE B 2 140 ? -1.436 13.868 -83.783 1.00 74.85 ? 140 PHE C O 1 +ATOM 3508 C CB . PHE B 2 140 ? -4.297 14.651 -82.923 1.00 70.10 ? 140 PHE C CB 1 +ATOM 3509 C CG . PHE B 2 140 ? -5.686 14.193 -82.553 1.00 72.99 ? 140 PHE C CG 1 +ATOM 3510 C CD1 . PHE B 2 140 ? -5.901 12.916 -82.057 1.00 66.88 ? 140 PHE C CD1 1 +ATOM 3511 C CD2 . PHE B 2 140 ? -6.781 15.027 -82.734 1.00 81.11 ? 140 PHE C CD2 1 +ATOM 3512 C CE1 . PHE B 2 140 ? -7.175 12.489 -81.726 1.00 63.54 ? 140 PHE C CE1 1 +ATOM 3513 C CE2 . PHE B 2 140 ? -8.063 14.601 -82.409 1.00 70.41 ? 140 PHE C CE2 1 +ATOM 3514 C CZ . PHE B 2 140 ? -8.258 13.331 -81.905 1.00 62.92 ? 140 PHE C CZ 1 +ATOM 3515 N N . GLU B 2 141 ? -1.067 15.152 -81.961 1.00 78.09 ? 141 GLU C N 1 +ATOM 3516 C CA . GLU B 2 141 ? 0.297 15.501 -82.332 1.00 81.27 ? 141 GLU C CA 1 +ATOM 3517 C C . GLU B 2 141 ? 1.306 14.447 -81.899 1.00 77.28 ? 141 GLU C C 1 +ATOM 3518 O O . GLU B 2 141 ? 2.479 14.542 -82.277 1.00 81.06 ? 141 GLU C O 1 +ATOM 3519 C CB . GLU B 2 141 ? 0.676 16.859 -81.727 1.00 86.17 ? 141 GLU C CB 1 +ATOM 3520 C CG . GLU B 2 141 ? 0.518 18.034 -82.696 1.00 95.55 ? 141 GLU C CG 1 +ATOM 3521 C CD . GLU B 2 141 ? 0.679 19.391 -82.019 1.00 91.71 ? 141 GLU C CD 1 +ATOM 3522 O OE1 . GLU B 2 141 ? 1.833 19.792 -81.753 1.00 94.55 ? 141 GLU C OE1 1 +ATOM 3523 O OE2 . GLU B 2 141 ? -0.344 20.059 -81.752 1.00 81.55 ? 141 GLU C OE2 1 +ATOM 3524 N N . HIS B 2 142 ? 0.877 13.444 -81.128 1.00 71.75 ? 142 HIS C N 1 +ATOM 3525 C CA . HIS B 2 142 ? 1.757 12.361 -80.722 1.00 72.48 ? 142 HIS C CA 1 +ATOM 3526 C C . HIS B 2 142 ? 2.204 11.564 -81.947 1.00 76.35 ? 142 HIS C C 1 +ATOM 3527 O O . HIS B 2 142 ? 1.544 11.592 -82.986 1.00 78.37 ? 142 HIS C O 1 +ATOM 3528 C CB . HIS B 2 142 ? 1.029 11.440 -79.746 1.00 73.11 ? 142 HIS C CB 1 +ATOM 3529 C CG . HIS B 2 142 ? 1.935 10.700 -78.816 1.00 73.29 ? 142 HIS C CG 1 +ATOM 3530 N ND1 . HIS B 2 142 ? 2.582 11.310 -77.764 1.00 81.94 ? 142 HIS C ND1 1 +ATOM 3531 C CD2 . HIS B 2 142 ? 2.327 9.405 -78.802 1.00 67.29 ? 142 HIS C CD2 1 +ATOM 3532 C CE1 . HIS B 2 142 ? 3.318 10.415 -77.127 1.00 87.70 ? 142 HIS C CE1 1 +ATOM 3533 N NE2 . HIS B 2 142 ? 3.181 9.251 -77.738 1.00 72.72 ? 142 HIS C NE2 1 +ATOM 3534 N N . PRO B 2 143 ? 3.322 10.836 -81.850 1.00 78.08 ? 143 PRO C N 1 +ATOM 3535 C CA . PRO B 2 143 ? 3.702 9.912 -82.929 1.00 79.13 ? 143 PRO C CA 1 +ATOM 3536 C C . PRO B 2 143 ? 2.972 8.578 -82.900 1.00 72.64 ? 143 PRO C C 1 +ATOM 3537 O O . PRO B 2 143 ? 3.154 7.769 -83.819 1.00 64.05 ? 143 PRO C O 1 +ATOM 3538 C CB . PRO B 2 143 ? 5.207 9.711 -82.694 1.00 77.88 ? 143 PRO C CB 1 +ATOM 3539 C CG . PRO B 2 143 ? 5.396 9.956 -81.238 1.00 77.21 ? 143 PRO C CG 1 +ATOM 3540 C CD . PRO B 2 143 ? 4.421 11.043 -80.888 1.00 77.52 ? 143 PRO C CD 1 +ATOM 3541 N N . LEU B 2 144 ? 2.135 8.334 -81.897 1.00 73.20 ? 144 LEU C N 1 +ATOM 3542 C CA . LEU B 2 144 ? 1.331 7.121 -81.825 1.00 72.51 ? 144 LEU C CA 1 +ATOM 3543 C C . LEU B 2 144 ? -0.039 7.294 -82.460 1.00 74.48 ? 144 LEU C C 1 +ATOM 3544 O O . LEU B 2 144 ? -0.849 6.361 -82.429 1.00 73.81 ? 144 LEU C O 1 +ATOM 3545 C CB . LEU B 2 144 ? 1.162 6.678 -80.367 1.00 70.81 ? 144 LEU C CB 1 +ATOM 3546 C CG . LEU B 2 144 ? 1.701 5.306 -79.955 1.00 63.14 ? 144 LEU C CG 1 +ATOM 3547 C CD1 . LEU B 2 144 ? 0.625 4.538 -79.216 1.00 60.96 ? 144 LEU C CD1 1 +ATOM 3548 C CD2 . LEU B 2 144 ? 2.208 4.511 -81.149 1.00 62.07 ? 144 LEU C CD2 1 +ATOM 3549 N N . TYR B 2 145 ? -0.321 8.472 -83.009 1.00 74.90 ? 145 TYR C N 1 +ATOM 3550 C CA . TYR B 2 145 ? -1.601 8.756 -83.640 1.00 74.20 ? 145 TYR C CA 1 +ATOM 3551 C C . TYR B 2 145 ? -1.456 9.139 -85.106 1.00 78.71 ? 145 TYR C C 1 +ATOM 3552 O O . TYR B 2 145 ? -2.450 9.522 -85.732 1.00 81.29 ? 145 TYR C O 1 +ATOM 3553 C CB . TYR B 2 145 ? -2.344 9.863 -82.883 1.00 69.23 ? 145 TYR C CB 1 +ATOM 3554 C CG . TYR B 2 145 ? -3.095 9.392 -81.658 1.00 70.86 ? 145 TYR C CG 1 +ATOM 3555 C CD1 . TYR B 2 145 ? -2.459 8.690 -80.638 1.00 66.41 ? 145 TYR C CD1 1 +ATOM 3556 C CD2 . TYR B 2 145 ? -4.456 9.642 -81.530 1.00 73.50 ? 145 TYR C CD2 1 +ATOM 3557 C CE1 . TYR B 2 145 ? -3.163 8.258 -79.522 1.00 63.87 ? 145 TYR C CE1 1 +ATOM 3558 C CE2 . TYR B 2 145 ? -5.165 9.216 -80.423 1.00 67.56 ? 145 TYR C CE2 1 +ATOM 3559 C CZ . TYR B 2 145 ? -4.517 8.526 -79.424 1.00 65.14 ? 145 TYR C CZ 1 +ATOM 3560 O OH . TYR B 2 145 ? -5.240 8.109 -78.331 1.00 61.75 ? 145 TYR C OH 1 +ATOM 3561 N N . ARG B 2 146 ? -0.252 9.058 -85.670 1.00 74.41 ? 146 ARG C N 1 +ATOM 3562 C CA . ARG B 2 146 ? -0.038 9.405 -87.067 1.00 79.50 ? 146 ARG C CA 1 +ATOM 3563 C C . ARG B 2 146 ? 0.244 8.193 -87.945 1.00 85.63 ? 146 ARG C C 1 +ATOM 3564 O O . ARG B 2 146 ? 0.470 8.356 -89.149 1.00 86.80 ? 146 ARG C O 1 +ATOM 3565 C CB . ARG B 2 146 ? 1.103 10.425 -87.183 1.00 86.64 ? 146 ARG C CB 1 +ATOM 3566 C CG . ARG B 2 146 ? 1.233 11.304 -85.948 1.00 80.81 ? 146 ARG C CG 1 +ATOM 3567 C CD . ARG B 2 146 ? 2.013 12.598 -86.170 1.00 84.86 ? 146 ARG C CD 1 +ATOM 3568 N NE . ARG B 2 146 ? 1.171 13.638 -86.763 1.00 102.06 ? 146 ARG C NE 1 +ATOM 3569 C CZ . ARG B 2 146 ? 1.432 14.942 -86.713 1.00 97.45 ? 146 ARG C CZ 1 +ATOM 3570 N NH1 . ARG B 2 146 ? 2.515 15.383 -86.086 1.00 94.45 ? 146 ARG C NH1 1 +ATOM 3571 N NH2 . ARG B 2 146 ? 0.601 15.810 -87.282 1.00 81.18 ? 146 ARG C NH2 1 +ATOM 3572 N N . THR B 2 147 ? 0.217 6.985 -87.379 1.00 85.55 ? 147 THR C N 1 +ATOM 3573 C CA . THR B 2 147 ? 0.399 5.749 -88.134 1.00 84.23 ? 147 THR C CA 1 +ATOM 3574 C C . THR B 2 147 ? -0.651 5.588 -89.228 1.00 82.28 ? 147 THR C C 1 +ATOM 3575 O O . THR B 2 147 ? -1.805 5.263 -88.938 1.00 84.39 ? 147 THR C O 1 +ATOM 3576 C CB . THR B 2 147 ? 0.340 4.544 -87.198 1.00 78.33 ? 147 THR C CB 1 +ATOM 3577 O OG1 . THR B 2 147 ? 1.307 4.706 -86.154 1.00 88.46 ? 147 THR C OG1 1 +ATOM 3578 C CG2 . THR B 2 147 ? 0.640 3.266 -87.974 1.00 67.39 ? 147 THR C CG2 1 +ATOM 3579 N N . VAL B 2 148 ? -0.262 5.799 -90.486 1.00 85.59 ? 148 VAL C N 1 +ATOM 3580 C CA . VAL B 2 148 ? -1.206 5.672 -91.591 1.00 87.37 ? 148 VAL C CA 1 +ATOM 3581 C C . VAL B 2 148 ? -1.556 4.205 -91.827 1.00 82.44 ? 148 VAL C C 1 +ATOM 3582 O O . VAL B 2 148 ? -0.799 3.292 -91.470 1.00 84.27 ? 148 VAL C O 1 +ATOM 3583 C CB . VAL B 2 148 ? -0.634 6.315 -92.869 1.00 87.46 ? 148 VAL C CB 1 +ATOM 3584 C CG1 . VAL B 2 148 ? -0.314 7.788 -92.628 1.00 93.42 ? 148 VAL C CG1 1 +ATOM 3585 C CG2 . VAL B 2 148 ? 0.605 5.564 -93.344 1.00 70.21 ? 148 VAL C CG2 1 +ATOM 3586 N N . LEU B 2 149 ? -2.738 3.976 -92.402 1.00 78.47 ? 149 LEU C N 1 +ATOM 3587 C CA . LEU B 2 149 ? -3.129 2.640 -92.816 1.00 76.10 ? 149 LEU C CA 1 +ATOM 3588 C C . LEU B 2 149 ? -2.256 2.175 -93.977 1.00 77.14 ? 149 LEU C C 1 +ATOM 3589 O O . LEU B 2 149 ? -1.669 2.993 -94.689 1.00 75.95 ? 149 LEU C O 1 +ATOM 3590 C CB . LEU B 2 149 ? -4.595 2.609 -93.235 1.00 72.06 ? 149 LEU C CB 1 +ATOM 3591 C CG . LEU B 2 149 ? -5.635 3.225 -92.300 1.00 75.94 ? 149 LEU C CG 1 +ATOM 3592 C CD1 . LEU B 2 149 ? -6.997 3.204 -92.973 1.00 70.23 ? 149 LEU C CD1 1 +ATOM 3593 C CD2 . LEU B 2 149 ? -5.680 2.498 -90.963 1.00 79.37 ? 149 LEU C CD2 1 +ATOM 3594 N N . PRO B 2 150 ? -2.171 0.864 -94.204 1.00 80.41 ? 150 PRO C N 1 +ATOM 3595 C CA . PRO B 2 150 ? -1.511 0.372 -95.419 1.00 80.86 ? 150 PRO C CA 1 +ATOM 3596 C C . PRO B 2 150 ? -2.172 0.928 -96.673 1.00 76.71 ? 150 PRO C C 1 +ATOM 3597 O O . PRO B 2 150 ? -3.196 1.615 -96.629 1.00 75.77 ? 150 PRO C O 1 +ATOM 3598 C CB . PRO B 2 150 ? -1.664 -1.149 -95.318 1.00 74.76 ? 150 PRO C CB 1 +ATOM 3599 C CG . PRO B 2 150 ? -1.767 -1.412 -93.850 1.00 74.12 ? 150 PRO C CG 1 +ATOM 3600 C CD . PRO B 2 150 ? -2.520 -0.235 -93.284 1.00 75.07 ? 150 PRO C CD 1 +ATOM 3601 N N . ASP B 2 151 ? -1.543 0.649 -97.812 1.00 78.85 ? 151 ASP C N 1 +ATOM 3602 C CA . ASP B 2 151 ? -2.113 1.052 -99.086 1.00 75.31 ? 151 ASP C CA 1 +ATOM 3603 C C . ASP B 2 151 ? -3.484 0.410 -99.274 1.00 77.52 ? 151 ASP C C 1 +ATOM 3604 O O . ASP B 2 151 ? -3.889 -0.498 -98.541 1.00 82.85 ? 151 ASP C O 1 +ATOM 3605 C CB . ASP B 2 151 ? -1.196 0.651 -100.239 1.00 71.66 ? 151 ASP C CB 1 +ATOM 3606 C CG . ASP B 2 151 ? 0.073 1.460 -100.275 1.00 76.00 ? 151 ASP C CG 1 +ATOM 3607 O OD1 . ASP B 2 151 ? 0.067 2.593 -99.745 1.00 82.82 ? 151 ASP C OD1 1 +ATOM 3608 O OD2 . ASP B 2 151 ? 1.073 0.964 -100.834 1.00 71.74 ? 151 ASP C OD2 1 +ATOM 3609 N N . LEU B 2 152 ? -4.200 0.880 -100.280 1.00 64.57 ? 152 LEU C N 1 +ATOM 3610 C CA . LEU B 2 152 ? -5.532 0.369 -100.533 1.00 69.77 ? 152 LEU C CA 1 +ATOM 3611 C C . LEU B 2 152 ? -5.562 -0.359 -101.873 1.00 72.89 ? 152 LEU C C 1 +ATOM 3612 O O . LEU B 2 152 ? -4.525 -0.616 -102.495 1.00 79.07 ? 152 LEU C O 1 +ATOM 3613 C CB . LEU B 2 152 ? -6.543 1.512 -100.474 1.00 71.72 ? 152 LEU C CB 1 +ATOM 3614 C CG . LEU B 2 152 ? -6.640 2.179 -99.102 1.00 72.38 ? 152 LEU C CG 1 +ATOM 3615 C CD1 . LEU B 2 152 ? -5.749 3.415 -99.038 1.00 61.54 ? 152 LEU C CD1 1 +ATOM 3616 C CD2 . LEU B 2 152 ? -8.087 2.521 -98.785 1.00 65.43 ? 152 LEU C CD2 1 +ATOM 3617 N N . THR B 2 153 ? -6.770 -0.694 -102.311 1.00 74.12 ? 153 THR C N 1 +ATOM 3618 C CA . THR B 2 153 ? -7.039 -1.387 -103.562 1.00 76.82 ? 153 THR C CA 1 +ATOM 3619 C C . THR B 2 153 ? -8.539 -1.356 -103.783 1.00 78.82 ? 153 THR C C 1 +ATOM 3620 O O . THR B 2 153 ? -9.311 -1.314 -102.823 1.00 76.43 ? 153 THR C O 1 +ATOM 3621 C CB . THR B 2 153 ? -6.532 -2.839 -103.555 1.00 75.02 ? 153 THR C CB 1 +ATOM 3622 O OG1 . THR B 2 153 ? -7.051 -3.535 -104.695 1.00 73.99 ? 153 THR C OG1 1 +ATOM 3623 C CG2 . THR B 2 153 ? -6.967 -3.567 -102.301 1.00 68.89 ? 153 THR C CG2 1 +ATOM 3624 N N . GLU B 2 154 ? -8.944 -1.342 -105.057 1.00 81.53 ? 154 GLU C N 1 +ATOM 3625 C CA . GLU B 2 154 ? -10.367 -1.322 -105.383 1.00 85.63 ? 154 GLU C CA 1 +ATOM 3626 C C . GLU B 2 154 ? -11.129 -2.439 -104.679 1.00 83.81 ? 154 GLU C C 1 +ATOM 3627 O O . GLU B 2 154 ? -12.342 -2.314 -104.467 1.00 79.62 ? 154 GLU C O 1 +ATOM 3628 C CB . GLU B 2 154 ? -10.566 -1.418 -106.897 1.00 86.78 ? 154 GLU C CB 1 +ATOM 3629 C CG . GLU B 2 154 ? -11.318 -0.238 -107.495 1.00 89.61 ? 154 GLU C CG 1 +ATOM 3630 C CD . GLU B 2 154 ? -12.550 -0.664 -108.275 1.00 91.08 ? 154 GLU C CD 1 +ATOM 3631 O OE1 . GLU B 2 154 ? -13.648 -0.137 -107.995 1.00 84.65 ? 154 GLU C OE1 1 +ATOM 3632 O OE2 . GLU B 2 154 ? -12.417 -1.533 -109.165 1.00 91.29 ? 154 GLU C OE2 1 +ATOM 3633 N N . GLU B 2 155 ? -10.441 -3.522 -104.304 1.00 79.99 ? 155 GLU C N 1 +ATOM 3634 C CA . GLU B 2 155 ? -11.050 -4.574 -103.502 1.00 73.50 ? 155 GLU C CA 1 +ATOM 3635 C C . GLU B 2 155 ? -11.272 -4.140 -102.056 1.00 78.44 ? 155 GLU C C 1 +ATOM 3636 O O . GLU B 2 155 ? -12.064 -4.773 -101.348 1.00 75.30 ? 155 GLU C O 1 +ATOM 3637 C CB . GLU B 2 155 ? -10.174 -5.831 -103.554 1.00 68.83 ? 155 GLU C CB 1 +ATOM 3638 C CG . GLU B 2 155 ? -10.893 -7.130 -103.194 1.00 80.22 ? 155 GLU C CG 1 +ATOM 3639 C CD . GLU B 2 155 ? -10.723 -7.519 -101.733 1.00 83.61 ? 155 GLU C CD 1 +ATOM 3640 O OE1 . GLU B 2 155 ? -10.004 -6.802 -101.003 1.00 85.43 ? 155 GLU C OE1 1 +ATOM 3641 O OE2 . GLU B 2 155 ? -11.315 -8.538 -101.313 1.00 73.08 ? 155 GLU C OE2 1 +ATOM 3642 N N . ASP B 2 156 ? -10.618 -3.061 -101.607 1.00 79.65 ? 156 ASP C N 1 +ATOM 3643 C CA . ASP B 2 156 ? -10.765 -2.566 -100.241 1.00 77.24 ? 156 ASP C CA 1 +ATOM 3644 C C . ASP B 2 156 ? -11.821 -1.480 -100.098 1.00 73.84 ? 156 ASP C C 1 +ATOM 3645 O O . ASP B 2 156 ? -12.183 -1.140 -98.965 1.00 65.92 ? 156 ASP C O 1 +ATOM 3646 C CB . ASP B 2 156 ? -9.433 -2.014 -99.719 1.00 74.97 ? 156 ASP C CB 1 +ATOM 3647 C CG . ASP B 2 156 ? -8.469 -3.104 -99.318 1.00 77.83 ? 156 ASP C CG 1 +ATOM 3648 O OD1 . ASP B 2 156 ? -8.936 -4.217 -98.994 1.00 81.16 ? 156 ASP C OD1 1 +ATOM 3649 O OD2 . ASP B 2 156 ? -7.246 -2.841 -99.305 1.00 75.39 ? 156 ASP C OD2 1 +ATOM 3650 N N . THR B 2 157 ? -12.304 -0.915 -101.201 1.00 73.44 ? 157 THR C N 1 +ATOM 3651 C CA . THR B 2 157 ? -13.433 0.001 -101.141 1.00 69.60 ? 157 THR C CA 1 +ATOM 3652 C C . THR B 2 157 ? -14.720 -0.755 -100.823 1.00 69.48 ? 157 THR C C 1 +ATOM 3653 O O . THR B 2 157 ? -14.820 -1.975 -100.990 1.00 74.27 ? 157 THR C O 1 +ATOM 3654 C CB . THR B 2 157 ? -13.599 0.755 -102.464 1.00 68.58 ? 157 THR C CB 1 +ATOM 3655 O OG1 . THR B 2 157 ? -13.024 -0.009 -103.534 1.00 72.26 ? 157 THR C OG1 1 +ATOM 3656 C CG2 . THR B 2 157 ? -12.945 2.125 -102.397 1.00 66.87 ? 157 THR C CG2 1 +ATOM 3657 N N . LEU B 2 158 ? -15.718 -0.014 -100.349 1.00 59.40 ? 158 LEU C N 1 +ATOM 3658 C CA . LEU B 2 158 ? -16.990 -0.651 -100.041 1.00 60.69 ? 158 LEU C CA 1 +ATOM 3659 C C . LEU B 2 158 ? -17.857 -0.764 -101.291 1.00 66.90 ? 158 LEU C C 1 +ATOM 3660 O O . LEU B 2 158 ? -18.358 -1.845 -101.613 1.00 67.69 ? 158 LEU C O 1 +ATOM 3661 C CB . LEU B 2 158 ? -17.719 0.127 -98.946 1.00 56.23 ? 158 LEU C CB 1 +ATOM 3662 C CG . LEU B 2 158 ? -18.284 -0.703 -97.790 1.00 58.88 ? 158 LEU C CG 1 +ATOM 3663 C CD1 . LEU B 2 158 ? -19.494 -0.001 -97.208 1.00 55.36 ? 158 LEU C CD1 1 +ATOM 3664 C CD2 . LEU B 2 158 ? -18.623 -2.138 -98.201 1.00 58.41 ? 158 LEU C CD2 1 +ATOM 3665 N N . PHE B 2 159 ? -18.031 0.342 -102.009 1.00 63.89 ? 159 PHE C N 1 +ATOM 3666 C CA . PHE B 2 159 ? -18.855 0.380 -103.207 1.00 53.94 ? 159 PHE C CA 1 +ATOM 3667 C C . PHE B 2 159 ? -18.425 1.583 -104.030 1.00 55.40 ? 159 PHE C C 1 +ATOM 3668 O O . PHE B 2 159 ? -17.966 2.591 -103.487 1.00 55.26 ? 159 PHE C O 1 +ATOM 3669 C CB . PHE B 2 159 ? -20.361 0.459 -102.898 1.00 51.26 ? 159 PHE C CB 1 +ATOM 3670 C CG . PHE B 2 159 ? -20.762 1.542 -101.902 1.00 56.92 ? 159 PHE C CG 1 +ATOM 3671 C CD1 . PHE B 2 159 ? -19.892 2.030 -100.934 1.00 63.01 ? 159 PHE C CD1 1 +ATOM 3672 C CD2 . PHE B 2 159 ? -22.041 2.062 -101.942 1.00 57.99 ? 159 PHE C CD2 1 +ATOM 3673 C CE1 . PHE B 2 159 ? -20.283 3.005 -100.041 1.00 64.06 ? 159 PHE C CE1 1 +ATOM 3674 C CE2 . PHE B 2 159 ? -22.437 3.040 -101.050 1.00 58.69 ? 159 PHE C CE2 1 +ATOM 3675 C CZ . PHE B 2 159 ? -21.556 3.511 -100.099 1.00 59.43 ? 159 PHE C CZ 1 +ATOM 3676 N N . ASN B 2 160 ? -18.612 1.482 -105.341 1.00 61.22 ? 160 ASN C N 1 +ATOM 3677 C CA . ASN B 2 160 ? -18.168 2.525 -106.263 1.00 61.08 ? 160 ASN C CA 1 +ATOM 3678 C C . ASN B 2 160 ? -19.197 3.647 -106.308 1.00 54.94 ? 160 ASN C C 1 +ATOM 3679 O O . ASN B 2 160 ? -20.164 3.596 -107.067 1.00 58.04 ? 160 ASN C O 1 +ATOM 3680 C CB . ASN B 2 160 ? -17.910 1.941 -107.645 1.00 69.38 ? 160 ASN C CB 1 +ATOM 3681 C CG . ASN B 2 160 ? -16.818 0.881 -107.632 1.00 84.57 ? 160 ASN C CG 1 +ATOM 3682 O OD1 . ASN B 2 160 ? -16.452 0.361 -106.572 1.00 78.86 ? 160 ASN C OD1 1 +ATOM 3683 N ND2 . ASN B 2 160 ? -16.269 0.582 -108.805 1.00 81.66 ? 160 ASN C ND2 1 +ATOM 3684 N N . LEU B 2 161 ? -18.982 4.661 -105.459 1.00 48.05 ? 161 LEU C N 1 +ATOM 3685 C CA . LEU B 2 161 ? -19.713 5.932 -105.395 1.00 49.66 ? 161 LEU C CA 1 +ATOM 3686 C C . LEU B 2 161 ? -20.760 6.174 -106.482 1.00 51.20 ? 161 LEU C C 1 +ATOM 3687 O O . LEU B 2 161 ? -21.888 6.581 -106.181 1.00 46.19 ? 161 LEU C O 1 +ATOM 3688 C CB . LEU B 2 161 ? -18.710 7.090 -105.424 1.00 48.61 ? 161 LEU C CB 1 +ATOM 3689 C CG . LEU B 2 161 ? -19.218 8.480 -105.819 1.00 44.84 ? 161 LEU C CG 1 +ATOM 3690 C CD1 . LEU B 2 161 ? -20.172 9.061 -104.780 1.00 44.55 ? 161 LEU C CD1 1 +ATOM 3691 C CD2 . LEU B 2 161 ? -18.044 9.412 -106.056 1.00 45.01 ? 161 LEU C CD2 1 +ATOM 3692 N N . ASN B 2 162 ? -20.400 5.951 -107.749 1.00 54.45 ? 162 ASN C N 1 +ATOM 3693 C CA . ASN B 2 162 ? -21.356 6.095 -108.841 1.00 53.31 ? 162 ASN C CA 1 +ATOM 3694 C C . ASN B 2 162 ? -22.559 5.161 -108.702 1.00 57.62 ? 162 ASN C C 1 +ATOM 3695 O O . ASN B 2 162 ? -23.544 5.328 -109.432 1.00 55.39 ? 162 ASN C O 1 +ATOM 3696 C CB . ASN B 2 162 ? -20.639 5.851 -110.175 1.00 49.02 ? 162 ASN C CB 1 +ATOM 3697 C CG . ASN B 2 162 ? -21.484 6.233 -111.380 1.00 53.69 ? 162 ASN C CG 1 +ATOM 3698 O OD1 . ASN B 2 162 ? -22.283 7.168 -111.323 1.00 56.17 ? 162 ASN C OD1 1 +ATOM 3699 N ND2 . ASN B 2 162 ? -21.306 5.508 -112.483 1.00 55.38 ? 162 ASN C ND2 1 +ATOM 3700 N N . ALA B 2 163 ? -22.528 4.218 -107.756 1.00 57.08 ? 163 ALA C N 1 +ATOM 3701 C CA . ALA B 2 163 ? -23.603 3.254 -107.577 1.00 52.54 ? 163 ALA C CA 1 +ATOM 3702 C C . ALA B 2 163 ? -24.464 3.508 -106.352 1.00 48.17 ? 163 ALA C C 1 +ATOM 3703 O O . ALA B 2 163 ? -25.522 2.885 -106.228 1.00 51.08 ? 163 ALA C O 1 +ATOM 3704 C CB . ALA B 2 163 ? -23.034 1.829 -107.493 1.00 58.59 ? 163 ALA C CB 1 +ATOM 3705 N N . GLU B 2 164 ? -24.054 4.391 -105.446 1.00 47.40 ? 164 GLU C N 1 +ATOM 3706 C CA . GLU B 2 164 ? -24.964 4.807 -104.389 1.00 40.97 ? 164 GLU C CA 1 +ATOM 3707 C C . GLU B 2 164 ? -25.772 6.028 -104.786 1.00 42.28 ? 164 GLU C C 1 +ATOM 3708 O O . GLU B 2 164 ? -26.935 6.148 -104.387 1.00 40.18 ? 164 GLU C O 1 +ATOM 3709 C CB . GLU B 2 164 ? -24.204 5.112 -103.096 1.00 38.00 ? 164 GLU C CB 1 +ATOM 3710 C CG . GLU B 2 164 ? -25.123 5.585 -101.978 1.00 47.09 ? 164 GLU C CG 1 +ATOM 3711 C CD . GLU B 2 164 ? -24.412 5.822 -100.662 1.00 56.20 ? 164 GLU C CD 1 +ATOM 3712 O OE1 . GLU B 2 164 ? -23.189 6.066 -100.689 1.00 61.17 ? 164 GLU C OE1 1 +ATOM 3713 O OE2 . GLU B 2 164 ? -25.084 5.778 -99.603 1.00 46.33 ? 164 GLU C OE2 1 +ATOM 3714 N N . ILE B 2 165 ? -25.207 6.902 -105.622 1.00 43.75 ? 165 ILE C N 1 +ATOM 3715 C CA . ILE B 2 165 ? -25.941 8.062 -106.109 1.00 41.32 ? 165 ILE C CA 1 +ATOM 3716 C C . ILE B 2 165 ? -27.078 7.685 -107.040 1.00 42.91 ? 165 ILE C C 1 +ATOM 3717 O O . ILE B 2 165 ? -27.961 8.514 -107.292 1.00 38.00 ? 165 ILE C O 1 +ATOM 3718 C CB . ILE B 2 165 ? -24.965 9.019 -106.819 1.00 42.31 ? 165 ILE C CB 1 +ATOM 3719 C CG1 . ILE B 2 165 ? -24.355 8.353 -108.063 1.00 55.09 ? 165 ILE C CG1 1 +ATOM 3720 C CG2 . ILE B 2 165 ? -23.851 9.429 -105.865 1.00 38.00 ? 165 ILE C CG2 1 +ATOM 3721 C CD1 . ILE B 2 165 ? -24.999 8.737 -109.413 1.00 51.49 ? 165 ILE C CD1 1 +ATOM 3722 N N . ARG B 2 166 ? -27.110 6.437 -107.503 1.00 46.02 ? 166 ARG C N 1 +ATOM 3723 C CA . ARG B 2 166 ? -28.155 5.945 -108.386 1.00 45.42 ? 166 ARG C CA 1 +ATOM 3724 C C . ARG B 2 166 ? -29.305 5.316 -107.609 1.00 42.70 ? 166 ARG C C 1 +ATOM 3725 O O . ARG B 2 166 ? -30.273 4.851 -108.218 1.00 43.70 ? 166 ARG C O 1 +ATOM 3726 C CB . ARG B 2 166 ? -27.587 4.912 -109.371 1.00 51.28 ? 166 ARG C CB 1 +ATOM 3727 C CG . ARG B 2 166 ? -28.534 4.579 -110.542 1.00 58.89 ? 166 ARG C CG 1 +ATOM 3728 C CD . ARG B 2 166 ? -28.014 3.447 -111.399 1.00 66.45 ? 166 ARG C CD 1 +ATOM 3729 N NE . ARG B 2 166 ? -26.618 3.577 -111.785 1.00 72.46 ? 166 ARG C NE 1 +ATOM 3730 C CZ . ARG B 2 166 ? -25.677 2.799 -111.261 1.00 67.01 ? 166 ARG C CZ 1 +ATOM 3731 N NH1 . ARG B 2 166 ? -26.011 1.896 -110.347 1.00 69.68 ? 166 ARG C NH1 1 +ATOM 3732 N NH2 . ARG B 2 166 ? -24.412 2.920 -111.628 1.00 58.73 ? 166 ARG C NH2 1 +ATOM 3733 N N . LEU B 2 167 ? -29.214 5.274 -106.282 1.00 41.33 ? 167 LEU C N 1 +ATOM 3734 C CA . LEU B 2 167 ? -30.281 4.734 -105.452 1.00 38.06 ? 167 LEU C CA 1 +ATOM 3735 C C . LEU B 2 167 ? -31.217 5.807 -104.937 1.00 38.65 ? 167 LEU C C 1 +ATOM 3736 O O . LEU B 2 167 ? -32.358 5.498 -104.568 1.00 38.00 ? 167 LEU C O 1 +ATOM 3737 C CB . LEU B 2 167 ? -29.696 3.986 -104.252 1.00 38.00 ? 167 LEU C CB 1 +ATOM 3738 C CG . LEU B 2 167 ? -29.471 2.487 -104.414 1.00 38.00 ? 167 LEU C CG 1 +ATOM 3739 C CD1 . LEU B 2 167 ? -28.497 2.196 -105.538 1.00 43.63 ? 167 LEU C CD1 1 +ATOM 3740 C CD2 . LEU B 2 167 ? -28.968 1.916 -103.106 1.00 39.44 ? 167 LEU C CD2 1 +ATOM 3741 N N . TYR B 2 168 ? -30.778 7.043 -104.954 1.00 41.30 ? 168 TYR C N 1 +ATOM 3742 C CA . TYR B 2 168 ? -31.526 8.180 -104.471 1.00 41.26 ? 168 TYR C CA 1 +ATOM 3743 C C . TYR B 2 168 ? -32.238 8.854 -105.631 1.00 43.40 ? 168 TYR C C 1 +ATOM 3744 O O . TYR B 2 168 ? -31.853 8.690 -106.792 1.00 44.31 ? 168 TYR C O 1 +ATOM 3745 C CB . TYR B 2 168 ? -30.577 9.167 -103.774 1.00 39.51 ? 168 TYR C CB 1 +ATOM 3746 C CG . TYR B 2 168 ? -30.107 8.700 -102.406 1.00 40.05 ? 168 TYR C CG 1 +ATOM 3747 C CD1 . TYR B 2 168 ? -29.248 7.614 -102.276 1.00 40.65 ? 168 TYR C CD1 1 +ATOM 3748 C CD2 . TYR B 2 168 ? -30.541 9.328 -101.246 1.00 45.04 ? 168 TYR C CD2 1 +ATOM 3749 C CE1 . TYR B 2 168 ? -28.826 7.177 -101.036 1.00 40.14 ? 168 TYR C CE1 1 +ATOM 3750 C CE2 . TYR B 2 168 ? -30.125 8.892 -99.999 1.00 47.20 ? 168 TYR C CE2 1 +ATOM 3751 C CZ . TYR B 2 168 ? -29.268 7.816 -99.903 1.00 48.64 ? 168 TYR C CZ 1 +ATOM 3752 O OH . TYR B 2 168 ? -28.843 7.379 -98.668 1.00 70.86 ? 168 TYR C OH 1 +ATOM 3753 N N . PRO B 2 169 ? -33.289 9.620 -105.355 1.00 43.75 ? 169 PRO C N 1 +ATOM 3754 C CA . PRO B 2 169 ? -34.028 10.286 -106.437 1.00 50.22 ? 169 PRO C CA 1 +ATOM 3755 C C . PRO B 2 169 ? -33.182 11.257 -107.239 1.00 55.69 ? 169 PRO C C 1 +ATOM 3756 O O . PRO B 2 169 ? -32.003 11.473 -106.945 1.00 60.96 ? 169 PRO C O 1 +ATOM 3757 C CB . PRO B 2 169 ? -35.147 11.024 -105.692 1.00 52.65 ? 169 PRO C CB 1 +ATOM 3758 C CG . PRO B 2 169 ? -34.669 11.135 -104.290 1.00 54.99 ? 169 PRO C CG 1 +ATOM 3759 C CD . PRO B 2 169 ? -33.898 9.883 -104.044 1.00 49.13 ? 169 PRO C CD 1 +ATOM 3760 N N . LYS B 2 170 ? -33.782 11.865 -108.252 1.00 52.71 ? 170 LYS C N 1 +ATOM 3761 C CA . LYS B 2 170 ? -33.039 12.812 -109.070 1.00 51.31 ? 170 LYS C CA 1 +ATOM 3762 C C . LYS B 2 170 ? -32.604 14.061 -108.291 1.00 57.60 ? 170 LYS C C 1 +ATOM 3763 O O . LYS B 2 170 ? -31.924 14.902 -108.883 1.00 70.42 ? 170 LYS C O 1 +ATOM 3764 C CB . LYS B 2 170 ? -33.888 13.198 -110.287 1.00 62.91 ? 170 LYS C CB 1 +ATOM 3765 C CG . LYS B 2 170 ? -34.229 12.023 -111.217 1.00 65.89 ? 170 LYS C CG 1 +ATOM 3766 C CD . LYS B 2 170 ? -34.650 12.488 -112.618 1.00 62.35 ? 170 LYS C CD 1 +ATOM 3767 C CE . LYS B 2 170 ? -33.479 12.974 -113.462 1.00 63.30 ? 170 LYS C CE 1 +ATOM 3768 N NZ . LYS B 2 170 ? -32.447 11.916 -113.624 1.00 70.20 ? 170 LYS C NZ 1 +ATOM 3769 N N . ALA B 2 171 ? -32.980 14.199 -107.011 1.00 55.23 ? 171 ALA C N 1 +ATOM 3770 C CA . ALA B 2 171 ? -32.549 15.278 -106.116 1.00 55.31 ? 171 ALA C CA 1 +ATOM 3771 C C . ALA B 2 171 ? -32.999 16.661 -106.590 1.00 68.94 ? 171 ALA C C 1 +ATOM 3772 O O . ALA B 2 171 ? -33.438 16.828 -107.734 1.00 67.25 ? 171 ALA C O 1 +ATOM 3773 C CB . ALA B 2 171 ? -31.025 15.261 -105.916 1.00 48.18 ? 171 ALA C CB 1 +ATOM 3774 N N . ALA B 2 172 ? -32.891 17.659 -105.711 1.00 74.56 ? 172 ALA C N 1 +ATOM 3775 C CA . ALA B 2 172 ? -33.279 19.034 -106.031 1.00 71.93 ? 172 ALA C CA 1 +ATOM 3776 C C . ALA B 2 172 ? -32.148 20.002 -105.694 1.00 70.17 ? 172 ALA C C 1 +ATOM 3777 O O . ALA B 2 172 ? -30.972 19.641 -105.772 1.00 65.80 ? 172 ALA C O 1 +ATOM 3778 C CB . ALA B 2 172 ? -34.562 19.424 -105.284 1.00 52.93 ? 172 ALA C CB 1 +ATOM 3779 N N . SER B 2 196 ? -16.159 19.406 -107.497 1.00 101.44 ? 196 SER C N 1 +ATOM 3780 C CA . SER B 2 196 ? -16.884 18.171 -107.756 1.00 92.96 ? 196 SER C CA 1 +ATOM 3781 C C . SER B 2 196 ? -17.393 17.579 -106.445 1.00 87.77 ? 196 SER C C 1 +ATOM 3782 O O . SER B 2 196 ? -18.444 16.936 -106.413 1.00 85.80 ? 196 SER C O 1 +ATOM 3783 C CB . SER B 2 196 ? -15.997 17.162 -108.498 1.00 82.11 ? 196 SER C CB 1 +ATOM 3784 O OG . SER B 2 196 ? -14.900 16.736 -107.704 1.00 74.43 ? 196 SER C OG 1 +ATOM 3785 N N . GLU B 2 197 ? -16.656 17.822 -105.363 1.00 95.01 ? 197 GLU C N 1 +ATOM 3786 C CA . GLU B 2 197 ? -16.952 17.215 -104.062 1.00 95.96 ? 197 GLU C CA 1 +ATOM 3787 C C . GLU B 2 197 ? -17.935 18.058 -103.246 1.00 80.57 ? 197 GLU C C 1 +ATOM 3788 O O . GLU B 2 197 ? -17.741 18.307 -102.056 1.00 63.28 ? 197 GLU C O 1 +ATOM 3789 C CB . GLU B 2 197 ? -15.653 16.979 -103.293 1.00 86.24 ? 197 GLU C CB 1 +ATOM 3790 C CG . GLU B 2 197 ? -14.802 15.825 -103.833 1.00 81.86 ? 197 GLU C CG 1 +ATOM 3791 C CD . GLU B 2 197 ? -15.616 14.562 -104.090 1.00 81.78 ? 197 GLU C CD 1 +ATOM 3792 O OE1 . GLU B 2 197 ? -16.293 14.082 -103.153 1.00 71.56 ? 197 GLU C OE1 1 +ATOM 3793 O OE2 . GLU B 2 197 ? -15.581 14.056 -105.237 1.00 71.78 ? 197 GLU C OE2 1 +ATOM 3794 N N . SER B 2 198 ? -19.012 18.498 -103.896 1.00 81.17 ? 198 SER C N 1 +ATOM 3795 C CA . SER B 2 198 ? -20.102 19.204 -103.237 1.00 76.97 ? 198 SER C CA 1 +ATOM 3796 C C . SER B 2 198 ? -21.212 18.264 -102.784 1.00 74.87 ? 198 SER C C 1 +ATOM 3797 O O . SER B 2 198 ? -22.323 18.724 -102.497 1.00 65.25 ? 198 SER C O 1 +ATOM 3798 C CB . SER B 2 198 ? -20.682 20.280 -104.157 1.00 81.53 ? 198 SER C CB 1 +ATOM 3799 O OG . SER B 2 198 ? -21.783 20.924 -103.538 1.00 75.01 ? 198 SER C OG 1 +ATOM 3800 N N . TYR B 2 199 ? -20.946 16.960 -102.761 1.00 76.86 ? 199 TYR C N 1 +ATOM 3801 C CA . TYR B 2 199 ? -21.907 16.002 -102.251 1.00 64.72 ? 199 TYR C CA 1 +ATOM 3802 C C . TYR B 2 199 ? -22.090 16.210 -100.751 1.00 59.28 ? 199 TYR C C 1 +ATOM 3803 O O . TYR B 2 199 ? -21.140 16.564 -100.046 1.00 64.52 ? 199 TYR C O 1 +ATOM 3804 C CB . TYR B 2 199 ? -21.433 14.577 -102.510 1.00 62.11 ? 199 TYR C CB 1 +ATOM 3805 C CG . TYR B 2 199 ? -21.145 14.267 -103.960 1.00 61.71 ? 199 TYR C CG 1 +ATOM 3806 C CD1 . TYR B 2 199 ? -21.857 14.877 -104.982 1.00 62.03 ? 199 TYR C CD1 1 +ATOM 3807 C CD2 . TYR B 2 199 ? -20.143 13.370 -104.303 1.00 62.45 ? 199 TYR C CD2 1 +ATOM 3808 C CE1 . TYR B 2 199 ? -21.587 14.590 -106.304 1.00 71.25 ? 199 TYR C CE1 1 +ATOM 3809 C CE2 . TYR B 2 199 ? -19.864 13.079 -105.616 1.00 63.40 ? 199 TYR C CE2 1 +ATOM 3810 C CZ . TYR B 2 199 ? -20.587 13.690 -106.615 1.00 72.47 ? 199 TYR C CZ 1 +ATOM 3811 O OH . TYR B 2 199 ? -20.303 13.397 -107.932 1.00 75.32 ? 199 TYR C OH 1 +ATOM 3812 N N . PRO B 2 200 ? -23.291 15.962 -100.235 1.00 51.36 ? 200 PRO C N 1 +ATOM 3813 C CA . PRO B 2 200 ? -23.538 16.170 -98.806 1.00 51.05 ? 200 PRO C CA 1 +ATOM 3814 C C . PRO B 2 200 ? -22.577 15.363 -97.948 1.00 55.98 ? 200 PRO C C 1 +ATOM 3815 O O . PRO B 2 200 ? -21.995 14.366 -98.380 1.00 58.67 ? 200 PRO C O 1 +ATOM 3816 C CB . PRO B 2 200 ? -24.981 15.693 -98.628 1.00 55.84 ? 200 PRO C CB 1 +ATOM 3817 C CG . PRO B 2 200 ? -25.598 15.884 -99.981 1.00 63.93 ? 200 PRO C CG 1 +ATOM 3818 C CD . PRO B 2 200 ? -24.507 15.555 -100.957 1.00 58.34 ? 200 PRO C CD 1 +ATOM 3819 N N . ASN B 2 201 ? -22.388 15.837 -96.712 1.00 56.51 ? 201 ASN C N 1 +ATOM 3820 C CA . ASN B 2 201 ? -21.410 15.213 -95.828 1.00 56.42 ? 201 ASN C CA 1 +ATOM 3821 C C . ASN B 2 201 ? -21.747 13.759 -95.533 1.00 55.77 ? 201 ASN C C 1 +ATOM 3822 O O . ASN B 2 201 ? -20.838 12.932 -95.389 1.00 51.99 ? 201 ASN C O 1 +ATOM 3823 C CB . ASN B 2 201 ? -21.302 16.004 -94.528 1.00 56.42 ? 201 ASN C CB 1 +ATOM 3824 C CG . ASN B 2 201 ? -20.792 17.394 -94.749 1.00 56.77 ? 201 ASN C CG 1 +ATOM 3825 O OD1 . ASN B 2 201 ? -20.104 17.658 -95.733 1.00 57.45 ? 201 ASN C OD1 1 +ATOM 3826 N ND2 . ASN B 2 201 ? -21.133 18.303 -93.844 1.00 63.17 ? 201 ASN C ND2 1 +ATOM 3827 N N . TRP B 2 202 ? -23.033 13.418 -95.446 1.00 49.92 ? 202 TRP C N 1 +ATOM 3828 C CA . TRP B 2 202 ? -23.382 12.029 -95.183 1.00 46.65 ? 202 TRP C CA 1 +ATOM 3829 C C . TRP B 2 202 ? -22.998 11.120 -96.335 1.00 47.34 ? 202 TRP C C 1 +ATOM 3830 O O . TRP B 2 202 ? -22.896 9.906 -96.144 1.00 54.09 ? 202 TRP C O 1 +ATOM 3831 C CB . TRP B 2 202 ? -24.873 11.900 -94.901 1.00 47.45 ? 202 TRP C CB 1 +ATOM 3832 C CG . TRP B 2 202 ? -25.720 12.239 -96.067 1.00 52.64 ? 202 TRP C CG 1 +ATOM 3833 C CD1 . TRP B 2 202 ? -26.293 13.442 -96.328 1.00 56.91 ? 202 TRP C CD1 1 +ATOM 3834 C CD2 . TRP B 2 202 ? -26.102 11.369 -97.139 1.00 53.32 ? 202 TRP C CD2 1 +ATOM 3835 N NE1 . TRP B 2 202 ? -27.017 13.381 -97.493 1.00 55.33 ? 202 TRP C NE1 1 +ATOM 3836 C CE2 . TRP B 2 202 ? -26.912 12.119 -98.013 1.00 54.03 ? 202 TRP C CE2 1 +ATOM 3837 C CE3 . TRP B 2 202 ? -25.839 10.031 -97.444 1.00 52.33 ? 202 TRP C CE3 1 +ATOM 3838 C CZ2 . TRP B 2 202 ? -27.460 11.577 -99.170 1.00 52.96 ? 202 TRP C CZ2 1 +ATOM 3839 C CZ3 . TRP B 2 202 ? -26.382 9.497 -98.595 1.00 53.49 ? 202 TRP C CZ3 1 +ATOM 3840 C CH2 . TRP B 2 202 ? -27.181 10.269 -99.444 1.00 50.91 ? 202 TRP C CH2 1 +ATOM 3841 N N . LEU B 2 203 ? -22.771 11.677 -97.517 1.00 47.04 ? 203 LEU C N 1 +ATOM 3842 C CA . LEU B 2 203 ? -22.332 10.876 -98.647 1.00 46.69 ? 203 LEU C CA 1 +ATOM 3843 C C . LEU B 2 203 ? -20.818 10.739 -98.665 1.00 48.30 ? 203 LEU C C 1 +ATOM 3844 O O . LEU B 2 203 ? -20.295 9.642 -98.875 1.00 51.72 ? 203 LEU C O 1 +ATOM 3845 C CB . LEU B 2 203 ? -22.821 11.497 -99.955 1.00 48.99 ? 203 LEU C CB 1 +ATOM 3846 C CG . LEU B 2 203 ? -22.548 10.702 -101.228 1.00 43.78 ? 203 LEU C CG 1 +ATOM 3847 C CD1 . LEU B 2 203 ? -22.760 9.220 -100.998 1.00 43.50 ? 203 LEU C CD1 1 +ATOM 3848 C CD2 . LEU B 2 203 ? -23.433 11.208 -102.347 1.00 48.60 ? 203 LEU C CD2 1 +ATOM 3849 N N . ARG B 2 204 ? -20.105 11.848 -98.453 1.00 47.73 ? 204 ARG C N 1 +ATOM 3850 C CA . ARG B 2 204 ? -18.657 11.774 -98.307 1.00 48.38 ? 204 ARG C CA 1 +ATOM 3851 C C . ARG B 2 204 ? -18.271 10.830 -97.177 1.00 51.45 ? 204 ARG C C 1 +ATOM 3852 O O . ARG B 2 204 ? -17.235 10.161 -97.250 1.00 51.87 ? 204 ARG C O 1 +ATOM 3853 C CB . ARG B 2 204 ? -18.081 13.171 -98.065 1.00 54.06 ? 204 ARG C CB 1 +ATOM 3854 C CG . ARG B 2 204 ? -16.844 13.497 -98.900 1.00 65.52 ? 204 ARG C CG 1 +ATOM 3855 C CD . ARG B 2 204 ? -17.164 14.481 -100.024 1.00 73.79 ? 204 ARG C CD 1 +ATOM 3856 N NE . ARG B 2 204 ? -17.831 15.680 -99.522 1.00 73.45 ? 204 ARG C NE 1 +ATOM 3857 C CZ . ARG B 2 204 ? -17.198 16.753 -99.056 1.00 74.36 ? 204 ARG C CZ 1 +ATOM 3858 N NH1 . ARG B 2 204 ? -17.893 17.795 -98.615 1.00 68.63 ? 204 ARG C NH1 1 +ATOM 3859 N NH2 . ARG B 2 204 ? -15.870 16.784 -99.028 1.00 71.89 ? 204 ARG C NH2 1 +ATOM 3860 N N . PHE B 2 205 ? -19.116 10.736 -96.148 1.00 50.11 ? 205 PHE C N 1 +ATOM 3861 C CA . PHE B 2 205 ? -18.877 9.803 -95.053 1.00 47.49 ? 205 PHE C CA 1 +ATOM 3862 C C . PHE B 2 205 ? -18.988 8.358 -95.522 1.00 45.94 ? 205 PHE C C 1 +ATOM 3863 O O . PHE B 2 205 ? -18.158 7.518 -95.154 1.00 46.08 ? 205 PHE C O 1 +ATOM 3864 C CB . PHE B 2 205 ? -19.862 10.115 -93.925 1.00 45.80 ? 205 PHE C CB 1 +ATOM 3865 C CG . PHE B 2 205 ? -20.061 9.002 -92.942 1.00 48.14 ? 205 PHE C CG 1 +ATOM 3866 C CD1 . PHE B 2 205 ? -19.002 8.503 -92.204 1.00 49.73 ? 205 PHE C CD1 1 +ATOM 3867 C CD2 . PHE B 2 205 ? -21.329 8.488 -92.719 1.00 47.00 ? 205 PHE C CD2 1 +ATOM 3868 C CE1 . PHE B 2 205 ? -19.200 7.491 -91.286 1.00 48.31 ? 205 PHE C CE1 1 +ATOM 3869 C CE2 . PHE B 2 205 ? -21.535 7.479 -91.801 1.00 42.65 ? 205 PHE C CE2 1 +ATOM 3870 C CZ . PHE B 2 205 ? -20.468 6.980 -91.083 1.00 47.72 ? 205 PHE C CZ 1 +ATOM 3871 N N . HIS B 2 206 ? -19.972 8.062 -96.376 1.00 48.46 ? 206 HIS C N 1 +ATOM 3872 C CA . HIS B 2 206 ? -20.207 6.683 -96.800 1.00 50.00 ? 206 HIS C CA 1 +ATOM 3873 C C . HIS B 2 206 ? -19.088 6.170 -97.700 1.00 49.32 ? 206 HIS C C 1 +ATOM 3874 O O . HIS B 2 206 ? -18.618 5.039 -97.531 1.00 48.30 ? 206 HIS C O 1 +ATOM 3875 C CB . HIS B 2 206 ? -21.551 6.577 -97.521 1.00 47.71 ? 206 HIS C CB 1 +ATOM 3876 C CG . HIS B 2 206 ? -22.730 6.562 -96.602 1.00 44.80 ? 206 HIS C CG 1 +ATOM 3877 N ND1 . HIS B 2 206 ? -23.856 7.323 -96.826 1.00 52.49 ? 206 HIS C ND1 1 +ATOM 3878 C CD2 . HIS B 2 206 ? -22.956 5.890 -95.450 1.00 46.17 ? 206 HIS C CD2 1 +ATOM 3879 C CE1 . HIS B 2 206 ? -24.728 7.116 -95.856 1.00 52.39 ? 206 HIS C CE1 1 +ATOM 3880 N NE2 . HIS B 2 206 ? -24.206 6.250 -95.007 1.00 50.77 ? 206 HIS C NE2 1 +ATOM 3881 N N . ILE B 2 207 ? -18.652 6.981 -98.667 1.00 49.20 ? 207 ILE C N 1 +ATOM 3882 C CA . ILE B 2 207 ? -17.638 6.521 -99.607 1.00 54.13 ? 207 ILE C CA 1 +ATOM 3883 C C . ILE B 2 207 ? -16.290 6.338 -98.923 1.00 55.20 ? 207 ILE C C 1 +ATOM 3884 O O . ILE B 2 207 ? -15.422 5.630 -99.451 1.00 53.47 ? 207 ILE C O 1 +ATOM 3885 C CB . ILE B 2 207 ? -17.529 7.484 -100.807 1.00 53.39 ? 207 ILE C CB 1 +ATOM 3886 C CG1 . ILE B 2 207 ? -17.258 8.908 -100.333 1.00 54.09 ? 207 ILE C CG1 1 +ATOM 3887 C CG2 . ILE B 2 207 ? -18.797 7.446 -101.649 1.00 44.38 ? 207 ILE C CG2 1 +ATOM 3888 C CD1 . ILE B 2 207 ? -17.208 9.912 -101.461 1.00 52.06 ? 207 ILE C CD1 1 +ATOM 3889 N N . GLY B 2 208 ? -16.082 6.972 -97.766 1.00 50.57 ? 208 GLY C N 1 +ATOM 3890 C CA . GLY B 2 208 ? -14.832 6.834 -97.041 1.00 57.51 ? 208 GLY C CA 1 +ATOM 3891 C C . GLY B 2 208 ? -14.703 5.589 -96.189 1.00 55.39 ? 208 GLY C C 1 +ATOM 3892 O O . GLY B 2 208 ? -13.617 5.323 -95.665 1.00 54.21 ? 208 GLY C O 1 +ATOM 3893 N N . ILE B 2 209 ? -15.771 4.803 -96.065 1.00 52.71 ? 209 ILE C N 1 +ATOM 3894 C CA . ILE B 2 209 ? -15.730 3.569 -95.292 1.00 48.00 ? 209 ILE C CA 1 +ATOM 3895 C C . ILE B 2 209 ? -14.913 2.545 -96.065 1.00 50.72 ? 209 ILE C C 1 +ATOM 3896 O O . ILE B 2 209 ? -15.402 1.945 -97.028 1.00 57.65 ? 209 ILE C O 1 +ATOM 3897 C CB . ILE B 2 209 ? -17.138 3.020 -94.996 1.00 44.55 ? 209 ILE C CB 1 +ATOM 3898 C CG1 . ILE B 2 209 ? -18.062 4.101 -94.451 1.00 46.34 ? 209 ILE C CG1 1 +ATOM 3899 C CG2 . ILE B 2 209 ? -17.066 1.903 -93.982 1.00 47.22 ? 209 ILE C CG2 1 +ATOM 3900 C CD1 . ILE B 2 209 ? -19.475 3.604 -94.247 1.00 38.00 ? 209 ILE C CD1 1 +ATOM 3901 N N . ASN B 2 210 ? -13.649 2.386 -95.701 1.00 48.34 ? 210 ASN C N 1 +ATOM 3902 C CA . ASN B 2 210 ? -12.801 1.390 -96.329 1.00 50.56 ? 210 ASN C CA 1 +ATOM 3903 C C . ASN B 2 210 ? -12.645 0.177 -95.409 1.00 52.04 ? 210 ASN C C 1 +ATOM 3904 O O . ASN B 2 210 ? -13.304 0.066 -94.370 1.00 48.74 ? 210 ASN C O 1 +ATOM 3905 C CB . ASN B 2 210 ? -11.460 2.013 -96.703 1.00 60.75 ? 210 ASN C CB 1 +ATOM 3906 C CG . ASN B 2 210 ? -10.664 2.437 -95.496 1.00 65.93 ? 210 ASN C CG 1 +ATOM 3907 O OD1 . ASN B 2 210 ? -11.187 3.076 -94.585 1.00 61.55 ? 210 ASN C OD1 1 +ATOM 3908 N ND2 . ASN B 2 210 ? -9.387 2.076 -95.477 1.00 70.12 ? 210 ASN C ND2 1 +ATOM 3909 N N . ARG B 2 211 ? -11.748 -0.738 -95.794 1.00 60.57 ? 211 ARG C N 1 +ATOM 3910 C CA . ARG B 2 211 ? -11.582 -2.005 -95.081 1.00 62.49 ? 211 ARG C CA 1 +ATOM 3911 C C . ARG B 2 211 ? -11.150 -1.797 -93.632 1.00 60.60 ? 211 ARG C C 1 +ATOM 3912 O O . ARG B 2 211 ? -11.615 -2.503 -92.731 1.00 64.50 ? 211 ARG C O 1 +ATOM 3913 C CB . ARG B 2 211 ? -10.572 -2.890 -95.826 1.00 67.16 ? 211 ARG C CB 1 +ATOM 3914 C CG . ARG B 2 211 ? -9.965 -4.029 -94.996 1.00 64.67 ? 211 ARG C CG 1 +ATOM 3915 C CD . ARG B 2 211 ? -9.178 -5.031 -95.843 1.00 62.01 ? 211 ARG C CD 1 +ATOM 3916 N NE . ARG B 2 211 ? -10.011 -5.622 -96.889 1.00 73.09 ? 211 ARG C NE 1 +ATOM 3917 C CZ . ARG B 2 211 ? -10.659 -6.779 -96.779 1.00 71.89 ? 211 ARG C CZ 1 +ATOM 3918 N NH1 . ARG B 2 211 ? -10.576 -7.491 -95.663 1.00 66.13 ? 211 ARG C NH1 1 +ATOM 3919 N NH2 . ARG B 2 211 ? -11.397 -7.224 -97.789 1.00 68.63 ? 211 ARG C NH2 1 +ATOM 3920 N N . TYR B 2 212 ? -10.255 -0.845 -93.386 1.00 56.58 ? 212 TYR C N 1 +ATOM 3921 C CA . TYR B 2 212 ? -9.652 -0.722 -92.065 1.00 55.38 ? 212 TYR C CA 1 +ATOM 3922 C C . TYR B 2 212 ? -10.445 0.222 -91.166 1.00 53.62 ? 212 TYR C C 1 +ATOM 3923 O O . TYR B 2 212 ? -11.178 -0.229 -90.282 1.00 48.04 ? 212 TYR C O 1 +ATOM 3924 C CB . TYR B 2 212 ? -8.197 -0.275 -92.212 1.00 60.35 ? 212 TYR C CB 1 +ATOM 3925 C CG . TYR B 2 212 ? -7.418 -1.121 -93.204 1.00 60.63 ? 212 TYR C CG 1 +ATOM 3926 C CD1 . TYR B 2 212 ? -7.008 -2.410 -92.883 1.00 58.12 ? 212 TYR C CD1 1 +ATOM 3927 C CD2 . TYR B 2 212 ? -7.106 -0.635 -94.468 1.00 67.61 ? 212 TYR C CD2 1 +ATOM 3928 C CE1 . TYR B 2 212 ? -6.303 -3.188 -93.792 1.00 59.84 ? 212 TYR C CE1 1 +ATOM 3929 C CE2 . TYR B 2 212 ? -6.401 -1.408 -95.383 1.00 72.07 ? 212 TYR C CE2 1 +ATOM 3930 C CZ . TYR B 2 212 ? -6.004 -2.682 -95.039 1.00 65.33 ? 212 TYR C CZ 1 +ATOM 3931 O OH . TYR B 2 212 ? -5.304 -3.447 -95.943 1.00 62.38 ? 212 TYR C OH 1 +ATOM 3932 N N . GLU B 2 213 ? -10.280 1.525 -91.354 1.00 63.41 ? 213 GLU C N 1 +ATOM 3933 C CA . GLU B 2 213 ? -11.012 2.500 -90.561 1.00 61.53 ? 213 GLU C CA 1 +ATOM 3934 C C . GLU B 2 213 ? -12.399 2.744 -91.159 1.00 57.95 ? 213 GLU C C 1 +ATOM 3935 O O . GLU B 2 213 ? -12.666 2.445 -92.327 1.00 59.59 ? 213 GLU C O 1 +ATOM 3936 C CB . GLU B 2 213 ? -10.224 3.811 -90.462 1.00 67.43 ? 213 GLU C CB 1 +ATOM 3937 C CG . GLU B 2 213 ? -10.136 4.618 -91.765 1.00 67.45 ? 213 GLU C CG 1 +ATOM 3938 C CD . GLU B 2 213 ? -9.034 5.676 -91.749 1.00 72.17 ? 213 GLU C CD 1 +ATOM 3939 O OE1 . GLU B 2 213 ? -8.602 6.093 -90.651 1.00 74.43 ? 213 GLU C OE1 1 +ATOM 3940 O OE2 . GLU B 2 213 ? -8.612 6.107 -92.843 1.00 71.46 ? 213 GLU C OE2 1 +ATOM 3941 N N . LEU B 2 214 ? -13.302 3.257 -90.318 1.00 52.88 ? 214 LEU C N 1 +ATOM 3942 C CA . LEU B 2 214 ? -14.603 3.724 -90.779 1.00 46.88 ? 214 LEU C CA 1 +ATOM 3943 C C . LEU B 2 214 ? -14.565 5.170 -91.273 1.00 57.73 ? 214 LEU C C 1 +ATOM 3944 O O . LEU B 2 214 ? -15.506 5.605 -91.949 1.00 52.70 ? 214 LEU C O 1 +ATOM 3945 C CB . LEU B 2 214 ? -15.632 3.571 -89.659 1.00 38.00 ? 214 LEU C CB 1 +ATOM 3946 C CG . LEU B 2 214 ? -17.096 3.770 -90.026 1.00 38.00 ? 214 LEU C CG 1 +ATOM 3947 C CD1 . LEU B 2 214 ? -17.736 2.442 -90.282 1.00 38.00 ? 214 LEU C CD1 1 +ATOM 3948 C CD2 . LEU B 2 214 ? -17.802 4.477 -88.901 1.00 38.00 ? 214 LEU C CD2 1 +ATOM 3949 N N . TYR B 2 215 ? -13.509 5.919 -90.940 1.00 64.96 ? 215 TYR C N 1 +ATOM 3950 C CA . TYR B 2 215 ? -13.302 7.298 -91.372 1.00 63.40 ? 215 TYR C CA 1 +ATOM 3951 C C . TYR B 2 215 ? -11.870 7.707 -91.050 1.00 65.28 ? 215 TYR C C 1 +ATOM 3952 O O . TYR B 2 215 ? -11.325 7.294 -90.024 1.00 63.29 ? 215 TYR C O 1 +ATOM 3953 C CB . TYR B 2 215 ? -14.287 8.266 -90.698 1.00 59.90 ? 215 TYR C CB 1 +ATOM 3954 C CG . TYR B 2 215 ? -14.356 8.184 -89.180 1.00 64.25 ? 215 TYR C CG 1 +ATOM 3955 C CD1 . TYR B 2 215 ? -15.237 7.312 -88.553 1.00 66.68 ? 215 TYR C CD1 1 +ATOM 3956 C CD2 . TYR B 2 215 ? -13.553 8.987 -88.374 1.00 63.22 ? 215 TYR C CD2 1 +ATOM 3957 C CE1 . TYR B 2 215 ? -15.315 7.236 -87.163 1.00 66.48 ? 215 TYR C CE1 1 +ATOM 3958 C CE2 . TYR B 2 215 ? -13.625 8.916 -86.980 1.00 63.01 ? 215 TYR C CE2 1 +ATOM 3959 C CZ . TYR B 2 215 ? -14.509 8.036 -86.384 1.00 58.83 ? 215 TYR C CZ 1 +ATOM 3960 O OH . TYR B 2 215 ? -14.602 7.942 -85.012 1.00 50.26 ? 215 TYR C OH 1 +ATOM 3961 N N . SER B 2 216 ? -11.276 8.525 -91.922 1.00 69.32 ? 216 SER C N 1 +ATOM 3962 C CA . SER B 2 216 ? -9.895 8.970 -91.750 1.00 73.78 ? 216 SER C CA 1 +ATOM 3963 C C . SER B 2 216 ? -9.712 9.671 -90.402 1.00 74.66 ? 216 SER C C 1 +ATOM 3964 O O . SER B 2 216 ? -10.672 10.120 -89.768 1.00 78.60 ? 216 SER C O 1 +ATOM 3965 C CB . SER B 2 216 ? -9.474 9.882 -92.904 1.00 76.04 ? 216 SER C CB 1 +ATOM 3966 O OG . SER B 2 216 ? -9.931 11.210 -92.726 1.00 84.35 ? 216 SER C OG 1 +ATOM 3967 N N . ARG B 2 217 ? -8.453 9.737 -89.953 1.00 68.13 ? 217 ARG C N 1 +ATOM 3968 C CA . ARG B 2 217 ? -8.162 10.228 -88.605 1.00 72.24 ? 217 ARG C CA 1 +ATOM 3969 C C . ARG B 2 217 ? -8.704 11.632 -88.381 1.00 75.09 ? 217 ARG C C 1 +ATOM 3970 O O . ARG B 2 217 ? -9.550 11.852 -87.507 1.00 68.44 ? 217 ARG C O 1 +ATOM 3971 C CB . ARG B 2 217 ? -6.659 10.180 -88.335 1.00 60.66 ? 217 ARG C CB 1 +ATOM 3972 C CG . ARG B 2 217 ? -6.296 9.251 -87.200 1.00 58.39 ? 217 ARG C CG 1 +ATOM 3973 C CD . ARG B 2 217 ? -4.916 8.704 -87.394 1.00 59.83 ? 217 ARG C CD 1 +ATOM 3974 N NE . ARG B 2 217 ? -4.790 7.374 -86.813 1.00 72.72 ? 217 ARG C NE 1 +ATOM 3975 C CZ . ARG B 2 217 ? -3.662 6.674 -86.799 1.00 80.21 ? 217 ARG C CZ 1 +ATOM 3976 N NH1 . ARG B 2 217 ? -2.567 7.192 -87.331 1.00 80.20 ? 217 ARG C NH1 1 +ATOM 3977 N NH2 . ARG B 2 217 ? -3.628 5.467 -86.244 1.00 80.97 ? 217 ARG C NH2 1 +ATOM 3978 N N . HIS B 2 218 ? -8.243 12.595 -89.165 1.00 71.07 ? 218 HIS C N 1 +ATOM 3979 C CA . HIS B 2 218 ? -8.689 13.975 -89.028 1.00 77.25 ? 218 HIS C CA 1 +ATOM 3980 C C . HIS B 2 218 ? -9.392 14.387 -90.317 1.00 78.07 ? 218 HIS C C 1 +ATOM 3981 O O . HIS B 2 218 ? -8.877 15.196 -91.089 1.00 82.57 ? 218 HIS C O 1 +ATOM 3982 C CB . HIS B 2 218 ? -7.526 14.904 -88.686 1.00 77.50 ? 218 HIS C CB 1 +ATOM 3983 C CG . HIS B 2 218 ? -7.919 16.040 -87.794 1.00 79.98 ? 218 HIS C CG 1 +ATOM 3984 N ND1 . HIS B 2 218 ? -8.946 16.906 -88.104 1.00 65.48 ? 218 HIS C ND1 1 +ATOM 3985 C CD2 . HIS B 2 218 ? -7.450 16.429 -86.584 1.00 76.62 ? 218 HIS C CD2 1 +ATOM 3986 C CE1 . HIS B 2 218 ? -9.080 17.792 -87.134 1.00 70.61 ? 218 HIS C CE1 1 +ATOM 3987 N NE2 . HIS B 2 218 ? -8.185 17.524 -86.198 1.00 72.65 ? 218 HIS C NE2 1 +ATOM 3988 N N . ASN B 2 219 ? -10.564 13.802 -90.555 1.00 78.71 ? 219 ASN C N 1 +ATOM 3989 C CA . ASN B 2 219 ? -11.355 14.147 -91.724 1.00 75.88 ? 219 ASN C CA 1 +ATOM 3990 C C . ASN B 2 219 ? -12.035 15.499 -91.520 1.00 72.98 ? 219 ASN C C 1 +ATOM 3991 O O . ASN B 2 219 ? -12.449 15.835 -90.407 1.00 74.72 ? 219 ASN C O 1 +ATOM 3992 C CB . ASN B 2 219 ? -12.414 13.079 -91.991 1.00 72.11 ? 219 ASN C CB 1 +ATOM 3993 C CG . ASN B 2 219 ? -12.751 12.944 -93.469 1.00 71.91 ? 219 ASN C CG 1 +ATOM 3994 O OD1 . ASN B 2 219 ? -13.745 13.495 -93.951 1.00 63.77 ? 219 ASN C OD1 1 +ATOM 3995 N ND2 . ASN B 2 219 ? -11.923 12.199 -94.193 1.00 74.99 ? 219 ASN C ND2 1 +ATOM 3996 N N . PRO B 2 220 ? -12.171 16.292 -92.584 1.00 68.98 ? 220 PRO C N 1 +ATOM 3997 C CA . PRO B 2 220 ? -12.929 17.542 -92.470 1.00 66.28 ? 220 PRO C CA 1 +ATOM 3998 C C . PRO B 2 220 ? -14.427 17.339 -92.571 1.00 68.29 ? 220 PRO C C 1 +ATOM 3999 O O . PRO B 2 220 ? -15.186 18.253 -92.221 1.00 66.40 ? 220 PRO C O 1 +ATOM 4000 C CB . PRO B 2 220 ? -12.410 18.370 -93.652 1.00 74.26 ? 220 PRO C CB 1 +ATOM 4001 C CG . PRO B 2 220 ? -12.010 17.353 -94.675 1.00 80.95 ? 220 PRO C CG 1 +ATOM 4002 C CD . PRO B 2 220 ? -11.605 16.097 -93.932 1.00 75.04 ? 220 PRO C CD 1 +ATOM 4003 N N . VAL B 2 221 ? -14.873 16.161 -92.999 1.00 69.77 ? 221 VAL C N 1 +ATOM 4004 C CA . VAL B 2 221 ? -16.299 15.901 -93.146 1.00 66.02 ? 221 VAL C CA 1 +ATOM 4005 C C . VAL B 2 221 ? -16.889 15.349 -91.863 1.00 61.67 ? 221 VAL C C 1 +ATOM 4006 O O . VAL B 2 221 ? -17.956 15.788 -91.430 1.00 61.20 ? 221 VAL C O 1 +ATOM 4007 C CB . VAL B 2 221 ? -16.543 14.940 -94.326 1.00 56.79 ? 221 VAL C CB 1 +ATOM 4008 C CG1 . VAL B 2 221 ? -17.970 14.409 -94.295 1.00 56.86 ? 221 VAL C CG1 1 +ATOM 4009 C CG2 . VAL B 2 221 ? -16.256 15.636 -95.641 1.00 67.88 ? 221 VAL C CG2 1 +ATOM 4010 N N . ILE B 2 222 ? -16.187 14.409 -91.230 1.00 59.97 ? 222 ILE C N 1 +ATOM 4011 C CA . ILE B 2 222 ? -16.668 13.845 -89.973 1.00 65.94 ? 222 ILE C CA 1 +ATOM 4012 C C . ILE B 2 222 ? -16.894 14.948 -88.953 1.00 72.53 ? 222 ILE C C 1 +ATOM 4013 O O . ILE B 2 222 ? -17.858 14.912 -88.176 1.00 69.63 ? 222 ILE C O 1 +ATOM 4014 C CB . ILE B 2 222 ? -15.680 12.786 -89.456 1.00 62.75 ? 222 ILE C CB 1 +ATOM 4015 C CG1 . ILE B 2 222 ? -15.525 11.686 -90.495 1.00 59.52 ? 222 ILE C CG1 1 +ATOM 4016 C CG2 . ILE B 2 222 ? -16.177 12.186 -88.156 1.00 62.89 ? 222 ILE C CG2 1 +ATOM 4017 C CD1 . ILE B 2 222 ? -16.810 10.936 -90.726 1.00 64.14 ? 222 ILE C CD1 1 +ATOM 4018 N N . ALA B 2 223 ? -16.041 15.971 -88.970 1.00 71.04 ? 223 ALA C N 1 +ATOM 4019 C CA . ALA B 2 223 ? -16.295 17.138 -88.138 1.00 70.66 ? 223 ALA C CA 1 +ATOM 4020 C C . ALA B 2 223 ? -17.536 17.876 -88.623 1.00 70.77 ? 223 ALA C C 1 +ATOM 4021 O O . ALA B 2 223 ? -18.421 18.214 -87.829 1.00 65.21 ? 223 ALA C O 1 +ATOM 4022 C CB . ALA B 2 223 ? -15.074 18.058 -88.138 1.00 71.41 ? 223 ALA C CB 1 +ATOM 4023 N N . ALA B 2 224 ? -17.641 18.086 -89.939 1.00 68.29 ? 224 ALA C N 1 +ATOM 4024 C CA . ALA B 2 224 ? -18.786 18.801 -90.489 1.00 66.30 ? 224 ALA C CA 1 +ATOM 4025 C C . ALA B 2 224 ? -20.045 17.947 -90.482 1.00 64.07 ? 224 ALA C C 1 +ATOM 4026 O O . ALA B 2 224 ? -21.156 18.486 -90.421 1.00 61.45 ? 224 ALA C O 1 +ATOM 4027 C CB . ALA B 2 224 ? -18.478 19.270 -91.908 1.00 63.27 ? 224 ALA C CB 1 +ATOM 4028 N N . LEU B 2 225 ? -19.900 16.624 -90.569 1.00 60.43 ? 225 LEU C N 1 +ATOM 4029 C CA . LEU B 2 225 ? -21.071 15.759 -90.496 1.00 61.54 ? 225 LEU C CA 1 +ATOM 4030 C C . LEU B 2 225 ? -21.758 15.903 -89.144 1.00 66.67 ? 225 LEU C C 1 +ATOM 4031 O O . LEU B 2 225 ? -22.994 15.920 -89.064 1.00 65.67 ? 225 LEU C O 1 +ATOM 4032 C CB . LEU B 2 225 ? -20.668 14.307 -90.775 1.00 57.56 ? 225 LEU C CB 1 +ATOM 4033 C CG . LEU B 2 225 ? -21.748 13.257 -91.059 1.00 50.14 ? 225 LEU C CG 1 +ATOM 4034 C CD1 . LEU B 2 225 ? -22.276 12.638 -89.781 1.00 63.58 ? 225 LEU C CD1 1 +ATOM 4035 C CD2 . LEU B 2 225 ? -22.894 13.866 -91.855 1.00 51.74 ? 225 LEU C CD2 1 +ATOM 4036 N N . LEU B 2 226 ? -20.972 16.041 -88.070 1.00 64.12 ? 226 LEU C N 1 +ATOM 4037 C CA . LEU B 2 226 ? -21.551 16.270 -86.750 1.00 62.51 ? 226 LEU C CA 1 +ATOM 4038 C C . LEU B 2 226 ? -22.340 17.572 -86.713 1.00 63.23 ? 226 LEU C C 1 +ATOM 4039 O O . LEU B 2 226 ? -23.413 17.639 -86.101 1.00 55.47 ? 226 LEU C O 1 +ATOM 4040 C CB . LEU B 2 226 ? -20.444 16.285 -85.696 1.00 59.83 ? 226 LEU C CB 1 +ATOM 4041 C CG . LEU B 2 226 ? -19.693 14.975 -85.453 1.00 57.53 ? 226 LEU C CG 1 +ATOM 4042 C CD1 . LEU B 2 226 ? -18.588 15.188 -84.431 1.00 57.55 ? 226 LEU C CD1 1 +ATOM 4043 C CD2 . LEU B 2 226 ? -20.656 13.894 -84.986 1.00 55.89 ? 226 LEU C CD2 1 +ATOM 4044 N N . ARG B 2 227 ? -21.837 18.607 -87.395 1.00 66.86 ? 227 ARG C N 1 +ATOM 4045 C CA . ARG B 2 227 ? -22.501 19.907 -87.410 1.00 60.61 ? 227 ARG C CA 1 +ATOM 4046 C C . ARG B 2 227 ? -23.844 19.831 -88.122 1.00 60.24 ? 227 ARG C C 1 +ATOM 4047 O O . ARG B 2 227 ? -24.803 20.505 -87.726 1.00 53.99 ? 227 ARG C O 1 +ATOM 4048 C CB . ARG B 2 227 ? -21.604 20.934 -88.099 1.00 58.09 ? 227 ARG C CB 1 +ATOM 4049 C CG . ARG B 2 227 ? -20.246 21.115 -87.451 1.00 63.37 ? 227 ARG C CG 1 +ATOM 4050 C CD . ARG B 2 227 ? -19.281 21.838 -88.382 1.00 70.39 ? 227 ARG C CD 1 +ATOM 4051 N NE . ARG B 2 227 ? -17.967 22.022 -87.770 1.00 80.39 ? 227 ARG C NE 1 +ATOM 4052 C CZ . ARG B 2 227 ? -16.905 22.507 -88.407 1.00 78.99 ? 227 ARG C CZ 1 +ATOM 4053 N NH1 . ARG B 2 227 ? -15.750 22.642 -87.768 1.00 84.75 ? 227 ARG C NH1 1 +ATOM 4054 N NH2 . ARG B 2 227 ? -16.997 22.846 -89.687 1.00 74.86 ? 227 ARG C NH2 1 +ATOM 4055 N N . ASP B 2 228 ? -23.927 19.017 -89.177 1.00 61.48 ? 228 ASP C N 1 +ATOM 4056 C CA . ASP B 2 228 ? -25.177 18.884 -89.916 1.00 63.32 ? 228 ASP C CA 1 +ATOM 4057 C C . ASP B 2 228 ? -26.274 18.330 -89.021 1.00 65.07 ? 228 ASP C C 1 +ATOM 4058 O O . ASP B 2 228 ? -27.380 18.880 -88.959 1.00 67.26 ? 228 ASP C O 1 +ATOM 4059 C CB . ASP B 2 228 ? -24.981 17.982 -91.135 1.00 66.73 ? 228 ASP C CB 1 +ATOM 4060 C CG . ASP B 2 228 ? -24.252 18.676 -92.266 1.00 67.81 ? 228 ASP C CG 1 +ATOM 4061 O OD1 . ASP B 2 228 ? -24.181 19.922 -92.250 1.00 71.52 ? 228 ASP C OD1 1 +ATOM 4062 O OD2 . ASP B 2 228 ? -23.768 17.975 -93.181 1.00 64.50 ? 228 ASP C OD2 1 +ATOM 4063 N N . LEU B 2 229 ? -25.975 17.247 -88.302 1.00 59.39 ? 229 LEU C N 1 +ATOM 4064 C CA . LEU B 2 229 ? -26.975 16.635 -87.437 1.00 55.38 ? 229 LEU C CA 1 +ATOM 4065 C C . LEU B 2 229 ? -27.454 17.605 -86.364 1.00 56.27 ? 229 LEU C C 1 +ATOM 4066 O O . LEU B 2 229 ? -28.631 17.573 -85.981 1.00 47.93 ? 229 LEU C O 1 +ATOM 4067 C CB . LEU B 2 229 ? -26.389 15.370 -86.808 1.00 59.27 ? 229 LEU C CB 1 +ATOM 4068 C CG . LEU B 2 229 ? -25.694 14.430 -87.802 1.00 54.74 ? 229 LEU C CG 1 +ATOM 4069 C CD1 . LEU B 2 229 ? -25.139 13.177 -87.133 1.00 44.68 ? 229 LEU C CD1 1 +ATOM 4070 C CD2 . LEU B 2 229 ? -26.657 14.052 -88.912 1.00 61.83 ? 229 LEU C CD2 1 +ATOM 4071 N N . LEU B 2 230 ? -26.578 18.517 -85.923 1.00 60.90 ? 230 LEU C N 1 +ATOM 4072 C CA . LEU B 2 230 ? -26.935 19.466 -84.870 1.00 57.46 ? 230 LEU C CA 1 +ATOM 4073 C C . LEU B 2 230 ? -28.037 20.414 -85.318 1.00 53.86 ? 230 LEU C C 1 +ATOM 4074 O O . LEU B 2 230 ? -28.903 20.784 -84.517 1.00 52.92 ? 230 LEU C O 1 +ATOM 4075 C CB . LEU B 2 230 ? -25.704 20.277 -84.442 1.00 54.41 ? 230 LEU C CB 1 +ATOM 4076 C CG . LEU B 2 230 ? -24.492 19.595 -83.800 1.00 59.95 ? 230 LEU C CG 1 +ATOM 4077 C CD1 . LEU B 2 230 ? -23.332 20.558 -83.605 1.00 63.07 ? 230 LEU C CD1 1 +ATOM 4078 C CD2 . LEU B 2 230 ? -24.887 19.030 -82.470 1.00 56.43 ? 230 LEU C CD2 1 +ATOM 4079 N N . SER B 2 231 ? -28.018 20.823 -86.592 1.00 54.51 ? 231 SER C N 1 +ATOM 4080 C CA . SER B 2 231 ? -28.813 21.960 -87.031 1.00 58.31 ? 231 SER C CA 1 +ATOM 4081 C C . SER B 2 231 ? -29.613 21.761 -88.313 1.00 53.50 ? 231 SER C C 1 +ATOM 4082 O O . SER B 2 231 ? -30.457 22.613 -88.610 1.00 53.88 ? 231 SER C O 1 +ATOM 4083 C CB . SER B 2 231 ? -27.909 23.192 -87.214 1.00 62.21 ? 231 SER C CB 1 +ATOM 4084 O OG . SER B 2 231 ? -26.816 22.898 -88.064 1.00 65.10 ? 231 SER C OG 1 +ATOM 4085 N N . GLN B 2 232 ? -29.385 20.700 -89.084 1.00 52.28 ? 232 GLN C N 1 +ATOM 4086 C CA . GLN B 2 232 ? -30.133 20.537 -90.327 1.00 54.26 ? 232 GLN C CA 1 +ATOM 4087 C C . GLN B 2 232 ? -31.617 20.325 -90.041 1.00 49.73 ? 232 GLN C C 1 +ATOM 4088 O O . GLN B 2 232 ? -32.001 19.813 -88.988 1.00 52.66 ? 232 GLN C O 1 +ATOM 4089 C CB . GLN B 2 232 ? -29.575 19.375 -91.153 1.00 64.31 ? 232 GLN C CB 1 +ATOM 4090 C CG . GLN B 2 232 ? -30.002 19.390 -92.629 1.00 70.93 ? 232 GLN C CG 1 +ATOM 4091 C CD . GLN B 2 232 ? -29.212 20.368 -93.494 1.00 75.44 ? 232 GLN C CD 1 +ATOM 4092 O OE1 . GLN B 2 232 ? -29.128 21.562 -93.196 1.00 78.97 ? 232 GLN C OE1 1 +ATOM 4093 N NE2 . GLN B 2 232 ? -28.660 19.866 -94.593 1.00 61.85 ? 232 GLN C NE2 1 +ATOM 4094 N N . LYS B 2 233 ? -32.453 20.709 -91.005 1.00 50.78 ? 233 LYS C N 1 +ATOM 4095 C CA . LYS B 2 233 ? -33.896 20.686 -90.810 1.00 53.47 ? 233 LYS C CA 1 +ATOM 4096 C C . LYS B 2 233 ? -34.437 19.269 -90.911 1.00 57.25 ? 233 LYS C C 1 +ATOM 4097 O O . LYS B 2 233 ? -34.045 18.500 -91.792 1.00 60.10 ? 233 LYS C O 1 +ATOM 4098 C CB . LYS B 2 233 ? -34.592 21.581 -91.837 1.00 53.22 ? 233 LYS C CB 1 +ATOM 4099 C CG . LYS B 2 233 ? -36.092 21.730 -91.610 1.00 59.07 ? 233 LYS C CG 1 +ATOM 4100 C CD . LYS B 2 233 ? -36.699 22.794 -92.529 1.00 78.51 ? 233 LYS C CD 1 +ATOM 4101 C CE . LYS B 2 233 ? -38.179 23.043 -92.204 1.00 83.40 ? 233 LYS C CE 1 +ATOM 4102 N NZ . LYS B 2 233 ? -38.797 24.170 -92.978 1.00 62.55 ? 233 LYS C NZ 1 +ATOM 4103 N N . ILE B 2 234 ? -35.354 18.934 -90.009 1.00 59.14 ? 234 ILE C N 1 +ATOM 4104 C CA . ILE B 2 234 ? -35.951 17.603 -89.979 1.00 58.20 ? 234 ILE C CA 1 +ATOM 4105 C C . ILE B 2 234 ? -37.035 17.536 -91.044 1.00 52.27 ? 234 ILE C C 1 +ATOM 4106 O O . ILE B 2 234 ? -37.973 18.338 -91.038 1.00 63.42 ? 234 ILE C O 1 +ATOM 4107 C CB . ILE B 2 234 ? -36.521 17.279 -88.591 1.00 58.62 ? 234 ILE C CB 1 +ATOM 4108 C CG1 . ILE B 2 234 ? -35.415 17.305 -87.524 1.00 49.95 ? 234 ILE C CG1 1 +ATOM 4109 C CG2 . ILE B 2 234 ? -37.276 15.955 -88.622 1.00 50.07 ? 234 ILE C CG2 1 +ATOM 4110 C CD1 . ILE B 2 234 ? -34.294 16.309 -87.747 1.00 43.18 ? 234 ILE C CD1 1 +ATOM 4111 N N . SER B 2 235 ? -36.918 16.568 -91.952 1.00 51.72 ? 235 SER C N 1 +ATOM 4112 C CA . SER B 2 235 ? -37.899 16.435 -93.022 1.00 52.01 ? 235 SER C CA 1 +ATOM 4113 C C . SER B 2 235 ? -38.999 15.439 -92.676 1.00 51.40 ? 235 SER C C 1 +ATOM 4114 O O . SER B 2 235 ? -40.184 15.775 -92.761 1.00 49.52 ? 235 SER C O 1 +ATOM 4115 C CB . SER B 2 235 ? -37.207 16.018 -94.320 1.00 51.26 ? 235 SER C CB 1 +ATOM 4116 O OG . SER B 2 235 ? -36.773 14.675 -94.240 1.00 50.40 ? 235 SER C OG 1 +ATOM 4117 N N . SER B 2 236 ? -38.629 14.217 -92.294 1.00 60.06 ? 236 SER C N 1 +ATOM 4118 C CA . SER B 2 236 ? -39.604 13.194 -91.938 1.00 61.62 ? 236 SER C CA 1 +ATOM 4119 C C . SER B 2 236 ? -39.076 12.355 -90.783 1.00 60.00 ? 236 SER C C 1 +ATOM 4120 O O . SER B 2 236 ? -37.874 12.097 -90.675 1.00 54.98 ? 236 SER C O 1 +ATOM 4121 C CB . SER B 2 236 ? -39.945 12.285 -93.126 1.00 56.63 ? 236 SER C CB 1 +ATOM 4122 O OG . SER B 2 236 ? -40.892 11.299 -92.749 1.00 55.78 ? 236 SER C OG 1 +ATOM 4123 N N . VAL B 2 237 ? -39.997 11.907 -89.933 1.00 61.30 ? 237 VAL C N 1 +ATOM 4124 C CA . VAL B 2 237 ? -39.668 11.111 -88.759 1.00 56.36 ? 237 VAL C CA 1 +ATOM 4125 C C . VAL B 2 237 ? -40.472 9.821 -88.812 1.00 55.35 ? 237 VAL C C 1 +ATOM 4126 O O . VAL B 2 237 ? -41.682 9.846 -89.068 1.00 47.54 ? 237 VAL C O 1 +ATOM 4127 C CB . VAL B 2 237 ? -39.948 11.874 -87.451 1.00 47.84 ? 237 VAL C CB 1 +ATOM 4128 C CG1 . VAL B 2 237 ? -39.633 11.005 -86.261 1.00 49.90 ? 237 VAL C CG1 1 +ATOM 4129 C CG2 . VAL B 2 237 ? -39.118 13.141 -87.398 1.00 46.77 ? 237 VAL C CG2 1 +ATOM 4130 N N . GLY B 2 238 ? -39.795 8.704 -88.592 1.00 56.25 ? 238 GLY C N 1 +ATOM 4131 C CA . GLY B 2 238 ? -40.442 7.407 -88.601 1.00 55.55 ? 238 GLY C CA 1 +ATOM 4132 C C . GLY B 2 238 ? -39.891 6.530 -87.500 1.00 53.97 ? 238 GLY C C 1 +ATOM 4133 O O . GLY B 2 238 ? -38.715 6.611 -87.139 1.00 53.09 ? 238 GLY C O 1 +ATOM 4134 N N . MET B 2 239 ? -40.765 5.688 -86.960 1.00 52.52 ? 239 MET C N 1 +ATOM 4135 C CA . MET B 2 239 ? -40.400 4.787 -85.880 1.00 59.15 ? 239 MET C CA 1 +ATOM 4136 C C . MET B 2 239 ? -39.861 3.477 -86.448 1.00 61.42 ? 239 MET C C 1 +ATOM 4137 O O . MET B 2 239 ? -40.430 2.917 -87.388 1.00 58.30 ? 239 MET C O 1 +ATOM 4138 C CB . MET B 2 239 ? -41.613 4.528 -84.984 1.00 61.94 ? 239 MET C CB 1 +ATOM 4139 C CG . MET B 2 239 ? -41.307 3.715 -83.743 1.00 74.29 ? 239 MET C CG 1 +ATOM 4140 S SD . MET B 2 239 ? -42.786 3.133 -82.886 1.00 92.57 ? 239 MET C SD 1 +ATOM 4141 C CE . MET B 2 239 ? -43.571 4.666 -82.463 1.00 56.92 ? 239 MET C CE 1 +ATOM 4142 N N . LYS B 2 240 ? -38.763 2.992 -85.865 1.00 63.90 ? 240 LYS C N 1 +ATOM 4143 C CA . LYS B 2 240 ? -38.191 1.701 -86.235 1.00 66.53 ? 240 LYS C CA 1 +ATOM 4144 C C . LYS B 2 240 ? -38.916 0.565 -85.520 1.00 75.03 ? 240 LYS C C 1 +ATOM 4145 O O . LYS B 2 240 ? -39.463 0.737 -84.427 1.00 86.41 ? 240 LYS C O 1 +ATOM 4146 C CB . LYS B 2 240 ? -36.699 1.650 -85.883 1.00 67.61 ? 240 LYS C CB 1 +ATOM 4147 C CG . LYS B 2 240 ? -35.960 0.407 -86.384 1.00 72.45 ? 240 LYS C CG 1 +ATOM 4148 C CD . LYS B 2 240 ? -34.532 0.345 -85.867 1.00 66.15 ? 240 LYS C CD 1 +ATOM 4149 C CE . LYS B 2 240 ? -33.583 1.103 -86.791 1.00 54.96 ? 240 LYS C CE 1 +ATOM 4150 N NZ . LYS B 2 240 ? -33.347 0.418 -88.098 1.00 42.38 ? 240 LYS C NZ 1 +ATOM 4151 N N . SER B 2 241 ? -38.921 -0.608 -86.146 1.00 69.01 ? 241 SER C N 1 +ATOM 4152 C CA . SER B 2 241 ? -39.532 -1.781 -85.544 1.00 80.89 ? 241 SER C CA 1 +ATOM 4153 C C . SER B 2 241 ? -38.458 -2.813 -85.213 1.00 80.56 ? 241 SER C C 1 +ATOM 4154 O O . SER B 2 241 ? -37.333 -2.762 -85.724 1.00 66.45 ? 241 SER C O 1 +ATOM 4155 C CB . SER B 2 241 ? -40.597 -2.381 -86.475 1.00 81.46 ? 241 SER C CB 1 +ATOM 4156 O OG . SER B 2 241 ? -41.387 -3.357 -85.813 1.00 76.04 ? 241 SER C OG 1 +ATOM 4157 N N . GLY B 2 242 ? -38.813 -3.736 -84.313 1.00 79.72 ? 242 GLY C N 1 +ATOM 4158 C CA . GLY B 2 242 ? -38.002 -4.893 -83.982 1.00 79.02 ? 242 GLY C CA 1 +ATOM 4159 C C . GLY B 2 242 ? -36.871 -4.672 -82.995 1.00 90.32 ? 242 GLY C C 1 +ATOM 4160 O O . GLY B 2 242 ? -36.216 -5.650 -82.607 1.00 89.77 ? 242 GLY C O 1 +ATOM 4161 N N . GLY B 2 243 ? -36.616 -3.434 -82.566 1.00 90.35 ? 243 GLY C N 1 +ATOM 4162 C CA . GLY B 2 243 ? -35.520 -3.153 -81.664 1.00 72.14 ? 243 GLY C CA 1 +ATOM 4163 C C . GLY B 2 243 ? -35.885 -3.359 -80.205 1.00 72.42 ? 243 GLY C C 1 +ATOM 4164 O O . GLY B 2 243 ? -37.014 -3.695 -79.849 1.00 66.07 ? 243 GLY C O 1 +ATOM 4165 N N . THR B 2 244 ? -34.891 -3.131 -79.344 1.00 80.50 ? 244 THR C N 1 +ATOM 4166 C CA . THR B 2 244 ? -35.106 -3.283 -77.907 1.00 72.16 ? 244 THR C CA 1 +ATOM 4167 C C . THR B 2 244 ? -35.970 -2.154 -77.353 1.00 67.96 ? 244 THR C C 1 +ATOM 4168 O O . THR B 2 244 ? -37.066 -2.392 -76.835 1.00 66.19 ? 244 THR C O 1 +ATOM 4169 C CB . THR B 2 244 ? -33.763 -3.345 -77.174 1.00 70.35 ? 244 THR C CB 1 +ATOM 4170 O OG1 . THR B 2 244 ? -32.691 -3.512 -78.117 1.00 65.46 ? 244 THR C OG1 1 +ATOM 4171 C CG2 . THR B 2 244 ? -33.760 -4.511 -76.199 1.00 66.16 ? 244 THR C CG2 1 +ATOM 4172 N N . GLN B 2 245 ? -35.500 -0.917 -77.475 1.00 69.23 ? 245 GLN C N 1 +ATOM 4173 C CA . GLN B 2 245 ? -36.170 0.276 -76.966 1.00 59.38 ? 245 GLN C CA 1 +ATOM 4174 C C . GLN B 2 245 ? -36.547 1.181 -78.136 1.00 60.77 ? 245 GLN C C 1 +ATOM 4175 O O . GLN B 2 245 ? -36.378 0.826 -79.301 1.00 72.12 ? 245 GLN C O 1 +ATOM 4176 C CB . GLN B 2 245 ? -35.280 1.023 -75.966 1.00 56.22 ? 245 GLN C CB 1 +ATOM 4177 C CG . GLN B 2 245 ? -35.450 0.596 -74.515 1.00 51.74 ? 245 GLN C CG 1 +ATOM 4178 C CD . GLN B 2 245 ? -34.274 1.012 -73.647 1.00 52.60 ? 245 GLN C CD 1 +ATOM 4179 O OE1 . GLN B 2 245 ? -33.822 2.156 -73.697 1.00 48.51 ? 245 GLN C OE1 1 +ATOM 4180 N NE2 . GLN B 2 245 ? -33.783 0.084 -72.835 1.00 54.94 ? 245 GLN C NE2 1 +ATOM 4181 N N . LEU B 2 246 ? -37.071 2.359 -77.811 1.00 55.18 ? 246 LEU C N 1 +ATOM 4182 C CA . LEU B 2 246 ? -37.543 3.292 -78.831 1.00 52.07 ? 246 LEU C CA 1 +ATOM 4183 C C . LEU B 2 246 ? -36.367 3.970 -79.524 1.00 53.02 ? 246 LEU C C 1 +ATOM 4184 O O . LEU B 2 246 ? -35.506 4.561 -78.865 1.00 49.26 ? 246 LEU C O 1 +ATOM 4185 C CB . LEU B 2 246 ? -38.463 4.337 -78.212 1.00 49.17 ? 246 LEU C CB 1 +ATOM 4186 C CG . LEU B 2 246 ? -39.038 5.346 -79.203 1.00 47.36 ? 246 LEU C CG 1 +ATOM 4187 C CD1 . LEU B 2 246 ? -40.201 4.747 -79.982 1.00 49.68 ? 246 LEU C CD1 1 +ATOM 4188 C CD2 . LEU B 2 246 ? -39.459 6.599 -78.460 1.00 48.13 ? 246 LEU C CD2 1 +ATOM 4189 N N . LYS B 2 247 ? -36.319 3.862 -80.853 1.00 54.34 ? 247 LYS C N 1 +ATOM 4190 C CA . LYS B 2 247 ? -35.318 4.550 -81.664 1.00 54.09 ? 247 LYS C CA 1 +ATOM 4191 C C . LYS B 2 247 ? -35.992 5.057 -82.931 1.00 57.28 ? 247 LYS C C 1 +ATOM 4192 O O . LYS B 2 247 ? -36.632 4.283 -83.649 1.00 63.95 ? 247 LYS C O 1 +ATOM 4193 C CB . LYS B 2 247 ? -34.123 3.632 -81.981 1.00 59.69 ? 247 LYS C CB 1 +ATOM 4194 C CG . LYS B 2 247 ? -34.458 2.142 -82.098 1.00 69.32 ? 247 LYS C CG 1 +ATOM 4195 C CD . LYS B 2 247 ? -33.218 1.249 -81.920 1.00 76.18 ? 247 LYS C CD 1 +ATOM 4196 C CE . LYS B 2 247 ? -33.612 -0.216 -81.660 1.00 85.43 ? 247 LYS C CE 1 +ATOM 4197 N NZ . LYS B 2 247 ? -32.469 -1.186 -81.525 1.00 86.43 ? 247 LYS C NZ 1 +ATOM 4198 N N . LEU B 2 248 ? -35.858 6.356 -83.195 1.00 51.08 ? 248 LEU C N 1 +ATOM 4199 C CA . LEU B 2 248 ? -36.537 7.015 -84.301 1.00 48.73 ? 248 LEU C CA 1 +ATOM 4200 C C . LEU B 2 248 ? -35.580 7.299 -85.455 1.00 49.40 ? 248 LEU C C 1 +ATOM 4201 O O . LEU B 2 248 ? -34.397 7.583 -85.249 1.00 43.09 ? 248 LEU C O 1 +ATOM 4202 C CB . LEU B 2 248 ? -37.176 8.319 -83.821 1.00 45.44 ? 248 LEU C CB 1 +ATOM 4203 C CG . LEU B 2 248 ? -38.661 8.229 -83.465 1.00 51.10 ? 248 LEU C CG 1 +ATOM 4204 C CD1 . LEU B 2 248 ? -38.974 6.981 -82.647 1.00 58.10 ? 248 LEU C CD1 1 +ATOM 4205 C CD2 . LEU B 2 248 ? -39.105 9.485 -82.724 1.00 44.02 ? 248 LEU C CD2 1 +ATOM 4206 N N . ILE B 2 249 ? -36.116 7.251 -86.675 1.00 55.15 ? 249 ILE C N 1 +ATOM 4207 C CA . ILE B 2 249 ? -35.351 7.520 -87.892 1.00 56.57 ? 249 ILE C CA 1 +ATOM 4208 C C . ILE B 2 249 ? -35.657 8.935 -88.360 1.00 51.38 ? 249 ILE C C 1 +ATOM 4209 O O . ILE B 2 249 ? -36.820 9.292 -88.588 1.00 47.87 ? 249 ILE C O 1 +ATOM 4210 C CB . ILE B 2 249 ? -35.653 6.500 -89.002 1.00 51.34 ? 249 ILE C CB 1 +ATOM 4211 C CG1 . ILE B 2 249 ? -34.955 5.176 -88.711 1.00 58.56 ? 249 ILE C CG1 1 +ATOM 4212 C CG2 . ILE B 2 249 ? -35.171 7.018 -90.347 1.00 49.42 ? 249 ILE C CG2 1 +ATOM 4213 C CD1 . ILE B 2 249 ? -35.742 4.253 -87.842 1.00 62.02 ? 249 ILE C CD1 1 +ATOM 4214 N N . MET B 2 250 ? -34.607 9.732 -88.512 1.00 48.31 ? 250 MET C N 1 +ATOM 4215 C CA . MET B 2 250 ? -34.707 11.102 -88.980 1.00 50.96 ? 250 MET C CA 1 +ATOM 4216 C C . MET B 2 250 ? -34.225 11.173 -90.421 1.00 56.63 ? 250 MET C C 1 +ATOM 4217 O O . MET B 2 250 ? -33.273 10.487 -90.800 1.00 48.73 ? 250 MET C O 1 +ATOM 4218 C CB . MET B 2 250 ? -33.871 12.038 -88.102 1.00 51.14 ? 250 MET C CB 1 +ATOM 4219 C CG . MET B 2 250 ? -34.164 11.929 -86.613 1.00 46.21 ? 250 MET C CG 1 +ATOM 4220 S SD . MET B 2 250 ? -35.417 13.068 -86.027 1.00 39.27 ? 250 MET C SD 1 +ATOM 4221 C CE . MET B 2 250 ? -35.778 12.414 -84.410 1.00 39.08 ? 250 MET C CE 1 +ATOM 4222 N N . SER B 2 251 ? -34.892 11.997 -91.221 1.00 66.27 ? 251 SER C N 1 +ATOM 4223 C CA . SER B 2 251 ? -34.469 12.306 -92.577 1.00 56.10 ? 251 SER C CA 1 +ATOM 4224 C C . SER B 2 251 ? -34.308 13.813 -92.697 1.00 53.59 ? 251 SER C C 1 +ATOM 4225 O O . SER B 2 251 ? -35.097 14.576 -92.131 1.00 56.54 ? 251 SER C O 1 +ATOM 4226 C CB . SER B 2 251 ? -35.479 11.783 -93.598 1.00 55.35 ? 251 SER C CB 1 +ATOM 4227 O OG . SER B 2 251 ? -35.517 10.366 -93.583 1.00 53.94 ? 251 SER C OG 1 +ATOM 4228 N N . PHE B 2 252 ? -33.297 14.247 -93.432 1.00 53.87 ? 252 PHE C N 1 +ATOM 4229 C CA . PHE B 2 252 ? -32.947 15.656 -93.445 1.00 58.44 ? 252 PHE C CA 1 +ATOM 4230 C C . PHE B 2 252 ? -33.203 16.283 -94.807 1.00 59.54 ? 252 PHE C C 1 +ATOM 4231 O O . PHE B 2 252 ? -33.555 15.620 -95.787 1.00 54.80 ? 252 PHE C O 1 +ATOM 4232 C CB . PHE B 2 252 ? -31.485 15.852 -93.041 1.00 58.59 ? 252 PHE C CB 1 +ATOM 4233 C CG . PHE B 2 252 ? -31.187 15.395 -91.655 1.00 52.73 ? 252 PHE C CG 1 +ATOM 4234 C CD1 . PHE B 2 252 ? -31.426 16.223 -90.577 1.00 56.03 ? 252 PHE C CD1 1 +ATOM 4235 C CD2 . PHE B 2 252 ? -30.670 14.137 -91.428 1.00 54.77 ? 252 PHE C CD2 1 +ATOM 4236 C CE1 . PHE B 2 252 ? -31.152 15.807 -89.295 1.00 67.63 ? 252 PHE C CE1 1 +ATOM 4237 C CE2 . PHE B 2 252 ? -30.393 13.711 -90.150 1.00 60.98 ? 252 PHE C CE2 1 +ATOM 4238 C CZ . PHE B 2 252 ? -30.633 14.547 -89.078 1.00 70.07 ? 252 PHE C CZ 1 +ATOM 4239 N N . GLN B 2 253 ? -33.003 17.600 -94.841 1.00 61.93 ? 253 GLN C N 1 +ATOM 4240 C CA . GLN B 2 253 ? -33.222 18.362 -96.059 1.00 67.98 ? 253 GLN C CA 1 +ATOM 4241 C C . GLN B 2 253 ? -32.265 17.944 -97.166 1.00 67.91 ? 253 GLN C C 1 +ATOM 4242 O O . GLN B 2 253 ? -32.599 18.080 -98.348 1.00 67.82 ? 253 GLN C O 1 +ATOM 4243 C CB . GLN B 2 253 ? -33.069 19.851 -95.740 1.00 65.29 ? 253 GLN C CB 1 +ATOM 4244 C CG . GLN B 2 253 ? -33.609 20.799 -96.778 1.00 66.29 ? 253 GLN C CG 1 +ATOM 4245 C CD . GLN B 2 253 ? -33.464 22.238 -96.341 1.00 77.25 ? 253 GLN C CD 1 +ATOM 4246 O OE1 . GLN B 2 253 ? -34.454 22.925 -96.086 1.00 85.12 ? 253 GLN C OE1 1 +ATOM 4247 N NE2 . GLN B 2 253 ? -32.223 22.700 -96.231 1.00 78.80 ? 253 GLN C NE2 1 +ATOM 4248 N N . ASN B 2 254 ? -31.105 17.392 -96.809 1.00 63.53 ? 254 ASN C N 1 +ATOM 4249 C CA . ASN B 2 254 ? -30.121 16.929 -97.778 1.00 57.90 ? 254 ASN C CA 1 +ATOM 4250 C C . ASN B 2 254 ? -30.168 15.419 -97.957 1.00 52.00 ? 254 ASN C C 1 +ATOM 4251 O O . ASN B 2 254 ? -29.130 14.785 -98.173 1.00 49.51 ? 254 ASN C O 1 +ATOM 4252 C CB . ASN B 2 254 ? -28.719 17.385 -97.379 1.00 57.73 ? 254 ASN C CB 1 +ATOM 4253 C CG . ASN B 2 254 ? -28.383 17.043 -95.953 1.00 50.84 ? 254 ASN C CG 1 +ATOM 4254 O OD1 . ASN B 2 254 ? -28.854 17.692 -95.022 1.00 56.41 ? 254 ASN C OD1 1 +ATOM 4255 N ND2 . ASN B 2 254 ? -27.562 16.025 -95.768 1.00 50.00 ? 254 ASN C ND2 1 +ATOM 4256 N N . TYR B 2 255 ? -31.351 14.826 -97.795 1.00 54.45 ? 255 TYR C N 1 +ATOM 4257 C CA . TYR B 2 255 ? -31.596 13.418 -98.099 1.00 64.87 ? 255 TYR C CA 1 +ATOM 4258 C C . TYR B 2 255 ? -30.792 12.467 -97.214 1.00 65.08 ? 255 TYR C C 1 +ATOM 4259 O O . TYR B 2 255 ? -30.951 11.242 -97.305 1.00 60.66 ? 255 TYR C O 1 +ATOM 4260 C CB . TYR B 2 255 ? -31.320 13.146 -99.583 1.00 55.20 ? 255 TYR C CB 1 +ATOM 4261 C CG . TYR B 2 255 ? -32.227 13.930 -100.510 1.00 50.90 ? 255 TYR C CG 1 +ATOM 4262 C CD1 . TYR B 2 255 ? -31.914 15.230 -100.878 1.00 57.79 ? 255 TYR C CD1 1 +ATOM 4263 C CD2 . TYR B 2 255 ? -33.393 13.367 -101.019 1.00 49.14 ? 255 TYR C CD2 1 +ATOM 4264 C CE1 . TYR B 2 255 ? -32.738 15.954 -101.723 1.00 64.19 ? 255 TYR C CE1 1 +ATOM 4265 C CE2 . TYR B 2 255 ? -34.222 14.082 -101.865 1.00 55.90 ? 255 TYR C CE2 1 +ATOM 4266 C CZ . TYR B 2 255 ? -33.890 15.375 -102.215 1.00 64.53 ? 255 TYR C CZ 1 +ATOM 4267 O OH . TYR B 2 255 ? -34.710 16.096 -103.059 1.00 64.51 ? 255 TYR C OH 1 +ATOM 4268 N N . GLY B 2 256 ? -29.930 13.008 -96.358 1.00 60.10 ? 256 GLY C N 1 +ATOM 4269 C CA . GLY B 2 256 ? -29.262 12.178 -95.382 1.00 56.77 ? 256 GLY C CA 1 +ATOM 4270 C C . GLY B 2 256 ? -30.200 11.763 -94.268 1.00 61.22 ? 256 GLY C C 1 +ATOM 4271 O O . GLY B 2 256 ? -31.217 12.402 -93.997 1.00 64.27 ? 256 GLY C O 1 +ATOM 4272 N N . GLN B 2 257 ? -29.851 10.662 -93.608 1.00 59.09 ? 257 GLN C N 1 +ATOM 4273 C CA . GLN B 2 257 ? -30.658 10.158 -92.509 1.00 52.10 ? 257 GLN C CA 1 +ATOM 4274 C C . GLN B 2 257 ? -29.746 9.735 -91.365 1.00 43.28 ? 257 GLN C C 1 +ATOM 4275 O O . GLN B 2 257 ? -28.524 9.631 -91.513 1.00 38.00 ? 257 GLN C O 1 +ATOM 4276 C CB . GLN B 2 257 ? -31.574 9.012 -92.970 1.00 48.59 ? 257 GLN C CB 1 +ATOM 4277 C CG . GLN B 2 257 ? -31.070 8.239 -94.176 1.00 52.51 ? 257 GLN C CG 1 +ATOM 4278 C CD . GLN B 2 257 ? -32.121 7.307 -94.745 1.00 54.74 ? 257 GLN C CD 1 +ATOM 4279 O OE1 . GLN B 2 257 ? -33.297 7.666 -94.847 1.00 47.38 ? 257 GLN C OE1 1 +ATOM 4280 N NE2 . GLN B 2 257 ? -31.707 6.090 -95.095 1.00 54.26 ? 257 GLN C NE2 1 +ATOM 4281 N N . ALA B 2 258 ? -30.361 9.511 -90.205 1.00 42.68 ? 258 ALA C N 1 +ATOM 4282 C CA . ALA B 2 258 ? -29.638 9.179 -88.987 1.00 38.00 ? 258 ALA C CA 1 +ATOM 4283 C C . ALA B 2 258 ? -30.595 8.511 -88.011 1.00 38.00 ? 258 ALA C C 1 +ATOM 4284 O O . ALA B 2 258 ? -31.815 8.664 -88.108 1.00 38.00 ? 258 ALA C O 1 +ATOM 4285 C CB . ALA B 2 258 ? -29.004 10.424 -88.360 1.00 38.00 ? 258 ALA C CB 1 +ATOM 4286 N N . LEU B 2 259 ? -30.024 7.746 -87.085 1.00 38.00 ? 259 LEU C N 1 +ATOM 4287 C CA . LEU B 2 259 ? -30.779 7.158 -85.989 1.00 38.00 ? 259 LEU C CA 1 +ATOM 4288 C C . LEU B 2 259 ? -30.867 8.136 -84.831 1.00 38.00 ? 259 LEU C C 1 +ATOM 4289 O O . LEU B 2 259 ? -29.965 8.943 -84.600 1.00 38.00 ? 259 LEU C O 1 +ATOM 4290 C CB . LEU B 2 259 ? -30.135 5.860 -85.504 1.00 40.63 ? 259 LEU C CB 1 +ATOM 4291 C CG . LEU B 2 259 ? -31.082 4.683 -85.281 1.00 42.26 ? 259 LEU C CG 1 +ATOM 4292 C CD1 . LEU B 2 259 ? -31.579 4.161 -86.625 1.00 53.34 ? 259 LEU C CD1 1 +ATOM 4293 C CD2 . LEU B 2 259 ? -30.411 3.583 -84.479 1.00 38.00 ? 259 LEU C CD2 1 +ATOM 4294 N N . PHE B 2 260 ? -31.936 8.012 -84.058 1.00 38.00 ? 260 PHE C N 1 +ATOM 4295 C CA . PHE B 2 260 ? -32.209 8.965 -82.995 1.00 44.05 ? 260 PHE C CA 1 +ATOM 4296 C C . PHE B 2 260 ? -32.608 8.223 -81.736 1.00 51.91 ? 260 PHE C C 1 +ATOM 4297 O O . PHE B 2 260 ? -33.620 7.516 -81.723 1.00 55.33 ? 260 PHE C O 1 +ATOM 4298 C CB . PHE B 2 260 ? -33.309 9.942 -83.408 1.00 46.88 ? 260 PHE C CB 1 +ATOM 4299 C CG . PHE B 2 260 ? -33.766 10.827 -82.298 1.00 48.60 ? 260 PHE C CG 1 +ATOM 4300 C CD1 . PHE B 2 260 ? -33.057 11.967 -81.975 1.00 48.20 ? 260 PHE C CD1 1 +ATOM 4301 C CD2 . PHE B 2 260 ? -34.935 10.542 -81.604 1.00 49.09 ? 260 PHE C CD2 1 +ATOM 4302 C CE1 . PHE B 2 260 ? -33.478 12.791 -80.953 1.00 53.32 ? 260 PHE C CE1 1 +ATOM 4303 C CE2 . PHE B 2 260 ? -35.365 11.365 -80.586 1.00 50.46 ? 260 PHE C CE2 1 +ATOM 4304 C CZ . PHE B 2 260 ? -34.635 12.491 -80.258 1.00 52.41 ? 260 PHE C CZ 1 +ATOM 4305 N N . LYS B 2 261 ? -31.822 8.397 -80.680 1.00 44.90 ? 261 LYS C N 1 +ATOM 4306 C CA . LYS B 2 261 ? -32.173 7.862 -79.380 1.00 44.61 ? 261 LYS C CA 1 +ATOM 4307 C C . LYS B 2 261 ? -32.424 9.014 -78.420 1.00 45.07 ? 261 LYS C C 1 +ATOM 4308 O O . LYS B 2 261 ? -31.550 9.879 -78.258 1.00 44.93 ? 261 LYS C O 1 +ATOM 4309 C CB . LYS B 2 261 ? -31.073 6.940 -78.852 1.00 50.62 ? 261 LYS C CB 1 +ATOM 4310 C CG . LYS B 2 261 ? -30.891 5.661 -79.672 1.00 51.27 ? 261 LYS C CG 1 +ATOM 4311 C CD . LYS B 2 261 ? -29.971 4.675 -78.959 1.00 59.97 ? 261 LYS C CD 1 +ATOM 4312 C CE . LYS B 2 261 ? -29.909 3.338 -79.694 1.00 74.88 ? 261 LYS C CE 1 +ATOM 4313 N NZ . LYS B 2 261 ? -28.978 2.363 -79.044 1.00 72.99 ? 261 LYS C NZ 1 +ATOM 4314 N N . PRO B 2 262 ? -33.601 9.069 -77.768 1.00 46.10 ? 262 PRO C N 1 +ATOM 4315 C CA . PRO B 2 262 ? -33.934 10.222 -76.922 1.00 48.98 ? 262 PRO C CA 1 +ATOM 4316 C C . PRO B 2 262 ? -33.197 10.229 -75.592 1.00 57.97 ? 262 PRO C C 1 +ATOM 4317 O O . PRO B 2 262 ? -32.267 9.447 -75.377 1.00 60.46 ? 262 PRO C O 1 +ATOM 4318 C CB . PRO B 2 262 ? -35.447 10.079 -76.706 1.00 42.74 ? 262 PRO C CB 1 +ATOM 4319 C CG . PRO B 2 262 ? -35.903 8.992 -77.629 1.00 38.00 ? 262 PRO C CG 1 +ATOM 4320 C CD . PRO B 2 262 ? -34.722 8.123 -77.856 1.00 40.40 ? 262 PRO C CD 1 +ATOM 4321 N N . MET B 2 263 ? -33.584 11.158 -74.714 1.00 56.02 ? 263 MET C N 1 +ATOM 4322 C CA . MET B 2 263 ? -32.903 11.313 -73.432 1.00 57.42 ? 263 MET C CA 1 +ATOM 4323 C C . MET B 2 263 ? -33.094 10.086 -72.550 1.00 59.80 ? 263 MET C C 1 +ATOM 4324 O O . MET B 2 263 ? -32.121 9.455 -72.117 1.00 59.71 ? 263 MET C O 1 +ATOM 4325 C CB . MET B 2 263 ? -33.389 12.571 -72.717 1.00 55.47 ? 263 MET C CB 1 +ATOM 4326 C CG . MET B 2 263 ? -32.711 12.762 -71.379 1.00 59.25 ? 263 MET C CG 1 +ATOM 4327 S SD . MET B 2 263 ? -32.316 14.485 -71.055 1.00 65.02 ? 263 MET C SD 1 +ATOM 4328 C CE . MET B 2 263 ? -30.932 14.313 -69.919 1.00 53.98 ? 263 MET C CE 1 +ATOM 4329 N N . LYS B 2 264 ? -34.347 9.790 -72.207 1.00 61.45 ? 264 LYS C N 1 +ATOM 4330 C CA . LYS B 2 264 ? -34.751 8.615 -71.438 1.00 67.17 ? 264 LYS C CA 1 +ATOM 4331 C C . LYS B 2 264 ? -34.341 8.717 -69.966 1.00 63.14 ? 264 LYS C C 1 +ATOM 4332 O O . LYS B 2 264 ? -35.128 8.358 -69.083 1.00 54.08 ? 264 LYS C O 1 +ATOM 4333 C CB . LYS B 2 264 ? -34.201 7.337 -72.085 1.00 62.79 ? 264 LYS C CB 1 +ATOM 4334 C CG . LYS B 2 264 ? -35.021 6.102 -71.760 1.00 64.11 ? 264 LYS C CG 1 +ATOM 4335 C CD . LYS B 2 264 ? -36.401 6.195 -72.415 1.00 69.70 ? 264 LYS C CD 1 +ATOM 4336 C CE . LYS B 2 264 ? -37.510 5.561 -71.560 1.00 70.68 ? 264 LYS C CE 1 +ATOM 4337 N NZ . LYS B 2 264 ? -37.765 6.252 -70.255 1.00 69.22 ? 264 LYS C NZ 1 +ATOM 4338 N N . GLN B 2 265 ? -33.136 9.209 -69.674 1.00 67.03 ? 265 GLN C N 1 +ATOM 4339 C CA . GLN B 2 265 ? -32.733 9.374 -68.282 1.00 70.27 ? 265 GLN C CA 1 +ATOM 4340 C C . GLN B 2 265 ? -31.730 10.519 -68.154 1.00 74.46 ? 265 GLN C C 1 +ATOM 4341 O O . GLN B 2 265 ? -31.059 10.900 -69.119 1.00 74.51 ? 265 GLN C O 1 +ATOM 4342 C CB . GLN B 2 265 ? -32.150 8.079 -67.697 1.00 66.81 ? 265 GLN C CB 1 +ATOM 4343 C CG . GLN B 2 265 ? -33.055 7.403 -66.659 1.00 67.80 ? 265 GLN C CG 1 +ATOM 4344 C CD . GLN B 2 265 ? -33.600 8.372 -65.612 1.00 86.09 ? 265 GLN C CD 1 +ATOM 4345 O OE1 . GLN B 2 265 ? -32.933 9.334 -65.226 1.00 94.40 ? 265 GLN C OE1 1 +ATOM 4346 N NE2 . GLN B 2 265 ? -34.818 8.109 -65.140 1.00 72.66 ? 265 GLN C NE2 1 +ATOM 4347 N N . THR B 2 266 ? -31.624 11.047 -66.928 1.00 72.45 ? 266 THR C N 1 +ATOM 4348 C CA . THR B 2 266 ? -30.829 12.228 -66.608 1.00 67.52 ? 266 THR C CA 1 +ATOM 4349 C C . THR B 2 266 ? -29.346 11.877 -66.471 1.00 67.05 ? 266 THR C C 1 +ATOM 4350 O O . THR B 2 266 ? -28.931 10.729 -66.649 1.00 79.60 ? 266 THR C O 1 +ATOM 4351 C CB . THR B 2 266 ? -31.328 12.858 -65.312 1.00 66.17 ? 266 THR C CB 1 +ATOM 4352 O OG1 . THR B 2 266 ? -30.924 12.041 -64.208 1.00 62.83 ? 266 THR C OG1 1 +ATOM 4353 C CG2 . THR B 2 266 ? -32.847 12.940 -65.325 1.00 57.50 ? 266 THR C CG2 1 +ATOM 4354 N N . ARG B 2 267 ? -28.534 12.872 -66.109 1.00 59.16 ? 267 ARG C N 1 +ATOM 4355 C CA . ARG B 2 267 ? -27.089 12.672 -66.037 1.00 68.83 ? 267 ARG C CA 1 +ATOM 4356 C C . ARG B 2 267 ? -26.640 12.118 -64.693 1.00 75.82 ? 267 ARG C C 1 +ATOM 4357 O O . ARG B 2 267 ? -25.847 11.173 -64.638 1.00 75.89 ? 267 ARG C O 1 +ATOM 4358 C CB . ARG B 2 267 ? -26.338 13.981 -66.316 1.00 70.33 ? 267 ARG C CB 1 +ATOM 4359 C CG . ARG B 2 267 ? -25.831 14.147 -67.746 1.00 67.51 ? 267 ARG C CG 1 +ATOM 4360 C CD . ARG B 2 267 ? -26.952 14.084 -68.773 1.00 66.06 ? 267 ARG C CD 1 +ATOM 4361 N NE . ARG B 2 267 ? -26.488 14.451 -70.108 1.00 58.61 ? 267 ARG C NE 1 +ATOM 4362 C CZ . ARG B 2 267 ? -26.507 15.687 -70.593 1.00 60.95 ? 267 ARG C CZ 1 +ATOM 4363 N NH1 . ARG B 2 267 ? -26.963 16.687 -69.853 1.00 72.50 ? 267 ARG C NH1 1 +ATOM 4364 N NH2 . ARG B 2 267 ? -26.068 15.926 -71.818 1.00 53.87 ? 267 ARG C NH2 1 +ATOM 4365 N N . GLU B 2 268 ? -27.128 12.698 -63.604 1.00 85.89 ? 268 GLU C N 1 +ATOM 4366 C CA . GLU B 2 268 ? -26.675 12.303 -62.279 1.00 90.04 ? 268 GLU C CA 1 +ATOM 4367 C C . GLU B 2 268 ? -27.291 10.991 -61.813 1.00 83.90 ? 268 GLU C C 1 +ATOM 4368 O O . GLU B 2 268 ? -27.040 10.580 -60.673 1.00 87.65 ? 268 GLU C O 1 +ATOM 4369 C CB . GLU B 2 268 ? -26.971 13.418 -61.267 1.00 92.76 ? 268 GLU C CB 1 +ATOM 4370 C CG . GLU B 2 268 ? -26.270 14.749 -61.562 1.00 82.82 ? 268 GLU C CG 1 +ATOM 4371 C CD . GLU B 2 268 ? -27.028 15.625 -62.550 1.00 95.87 ? 268 GLU C CD 1 +ATOM 4372 O OE1 . GLU B 2 268 ? -28.160 15.255 -62.941 1.00 97.06 ? 268 GLU C OE1 1 +ATOM 4373 O OE2 . GLU B 2 268 ? -26.487 16.684 -62.936 1.00 91.09 ? 268 GLU C OE2 1 +ATOM 4374 N N . GLN B 2 269 ? -28.070 10.323 -62.660 1.00 76.93 ? 269 GLN C N 1 +ATOM 4375 C CA . GLN B 2 269 ? -28.722 9.080 -62.282 1.00 79.74 ? 269 GLN C CA 1 +ATOM 4376 C C . GLN B 2 269 ? -27.836 7.883 -62.607 1.00 82.13 ? 269 GLN C C 1 +ATOM 4377 O O . GLN B 2 269 ? -27.075 7.889 -63.579 1.00 82.41 ? 269 GLN C O 1 +ATOM 4378 C CB . GLN B 2 269 ? -30.071 8.929 -62.988 1.00 68.57 ? 269 GLN C CB 1 +ATOM 4379 C CG . GLN B 2 269 ? -31.246 9.446 -62.183 1.00 73.77 ? 269 GLN C CG 1 +ATOM 4380 C CD . GLN B 2 269 ? -32.527 8.693 -62.493 1.00 83.51 ? 269 GLN C CD 1 +ATOM 4381 O OE1 . GLN B 2 269 ? -32.492 7.510 -62.831 1.00 88.27 ? 269 GLN C OE1 1 +ATOM 4382 N NE2 . GLN B 2 269 ? -33.664 9.375 -62.383 1.00 88.82 ? 269 GLN C NE2 1 +ATOM 4383 N N . GLU B 2 270 ? -27.941 6.853 -61.773 1.00 79.54 ? 270 GLU C N 1 +ATOM 4384 C CA . GLU B 2 270 ? -27.224 5.602 -61.959 1.00 68.92 ? 270 GLU C CA 1 +ATOM 4385 C C . GLU B 2 270 ? -28.217 4.473 -62.200 1.00 71.13 ? 270 GLU C C 1 +ATOM 4386 O O . GLU B 2 270 ? -29.368 4.533 -61.753 1.00 64.46 ? 270 GLU C O 1 +ATOM 4387 C CB . GLU B 2 270 ? -26.344 5.273 -60.750 1.00 66.44 ? 270 GLU C CB 1 +ATOM 4388 C CG . GLU B 2 270 ? -25.018 6.002 -60.744 1.00 65.71 ? 270 GLU C CG 1 +ATOM 4389 C CD . GLU B 2 270 ? -24.007 5.361 -59.816 1.00 74.29 ? 270 GLU C CD 1 +ATOM 4390 O OE1 . GLU B 2 270 ? -23.751 4.143 -59.946 1.00 78.43 ? 270 GLU C OE1 1 +ATOM 4391 O OE2 . GLU B 2 270 ? -23.494 6.072 -58.929 1.00 76.86 ? 270 GLU C OE2 1 +ATOM 4392 N N . THR B 2 271 ? -27.771 3.459 -62.936 1.00 68.79 ? 271 THR C N 1 +ATOM 4393 C CA . THR B 2 271 ? -28.587 2.268 -63.130 1.00 64.25 ? 271 THR C CA 1 +ATOM 4394 C C . THR B 2 271 ? -28.826 1.598 -61.781 1.00 62.97 ? 271 THR C C 1 +ATOM 4395 O O . THR B 2 271 ? -27.862 1.352 -61.041 1.00 60.19 ? 271 THR C O 1 +ATOM 4396 C CB . THR B 2 271 ? -27.901 1.284 -64.079 1.00 63.10 ? 271 THR C CB 1 +ATOM 4397 O OG1 . THR B 2 271 ? -27.718 1.896 -65.362 1.00 62.97 ? 271 THR C OG1 1 +ATOM 4398 C CG2 . THR B 2 271 ? -28.748 0.033 -64.249 1.00 64.97 ? 271 THR C CG2 1 +ATOM 4399 N N . PRO B 2 272 ? -30.073 1.285 -61.428 1.00 54.25 ? 272 PRO C N 1 +ATOM 4400 C CA . PRO B 2 272 ? -30.342 0.627 -60.148 1.00 52.81 ? 272 PRO C CA 1 +ATOM 4401 C C . PRO B 2 272 ? -29.504 -0.628 -60.013 1.00 63.53 ? 272 PRO C C 1 +ATOM 4402 O O . PRO B 2 272 ? -29.307 -1.358 -60.996 1.00 70.93 ? 272 PRO C O 1 +ATOM 4403 C CB . PRO B 2 272 ? -31.837 0.288 -60.233 1.00 45.60 ? 272 PRO C CB 1 +ATOM 4404 C CG . PRO B 2 272 ? -32.385 1.285 -61.171 1.00 47.54 ? 272 PRO C CG 1 +ATOM 4405 C CD . PRO B 2 272 ? -31.309 1.553 -62.180 1.00 46.97 ? 272 PRO C CD 1 +ATOM 4406 N N . PRO B 2 273 ? -28.975 -0.907 -58.822 1.00 58.03 ? 273 PRO C N 1 +ATOM 4407 C CA . PRO B 2 273 ? -28.118 -2.092 -58.670 1.00 58.84 ? 273 PRO C CA 1 +ATOM 4408 C C . PRO B 2 273 ? -28.851 -3.392 -58.933 1.00 55.72 ? 273 PRO C C 1 +ATOM 4409 O O . PRO B 2 273 ? -28.211 -4.384 -59.301 1.00 51.72 ? 273 PRO C O 1 +ATOM 4410 C CB . PRO B 2 273 ? -27.637 -1.995 -57.216 1.00 58.79 ? 273 PRO C CB 1 +ATOM 4411 C CG . PRO B 2 273 ? -27.860 -0.560 -56.828 1.00 59.35 ? 273 PRO C CG 1 +ATOM 4412 C CD . PRO B 2 273 ? -29.077 -0.130 -57.578 1.00 52.16 ? 273 PRO C CD 1 +ATOM 4413 N N . ASP B 2 274 ? -30.174 -3.409 -58.789 1.00 52.84 ? 274 ASP C N 1 +ATOM 4414 C CA . ASP B 2 274 ? -30.977 -4.609 -58.969 1.00 54.93 ? 274 ASP C CA 1 +ATOM 4415 C C . ASP B 2 274 ? -31.437 -4.796 -60.414 1.00 52.11 ? 274 ASP C C 1 +ATOM 4416 O O . ASP B 2 274 ? -32.224 -5.708 -60.692 1.00 47.25 ? 274 ASP C O 1 +ATOM 4417 C CB . ASP B 2 274 ? -32.180 -4.571 -58.018 1.00 58.21 ? 274 ASP C CB 1 +ATOM 4418 C CG . ASP B 2 274 ? -31.789 -4.200 -56.590 1.00 60.07 ? 274 ASP C CG 1 +ATOM 4419 O OD1 . ASP B 2 274 ? -31.538 -3.002 -56.338 1.00 68.16 ? 274 ASP C OD1 1 +ATOM 4420 O OD2 . ASP B 2 274 ? -31.740 -5.095 -55.717 1.00 51.59 ? 274 ASP C OD2 1 +ATOM 4421 N N . PHE B 2 275 ? -30.974 -3.951 -61.332 1.00 54.97 ? 275 PHE C N 1 +ATOM 4422 C CA . PHE B 2 275 ? -31.321 -4.068 -62.742 1.00 55.54 ? 275 PHE C CA 1 +ATOM 4423 C C . PHE B 2 275 ? -30.350 -5.013 -63.438 1.00 53.34 ? 275 PHE C C 1 +ATOM 4424 O O . PHE B 2 275 ? -29.131 -4.906 -63.260 1.00 49.11 ? 275 PHE C O 1 +ATOM 4425 C CB . PHE B 2 275 ? -31.303 -2.705 -63.439 1.00 55.87 ? 275 PHE C CB 1 +ATOM 4426 C CG . PHE B 2 275 ? -32.640 -2.011 -63.473 1.00 57.87 ? 275 PHE C CG 1 +ATOM 4427 C CD1 . PHE B 2 275 ? -33.730 -2.529 -62.791 1.00 59.28 ? 275 PHE C CD1 1 +ATOM 4428 C CD2 . PHE B 2 275 ? -32.812 -0.854 -64.219 1.00 55.01 ? 275 PHE C CD2 1 +ATOM 4429 C CE1 . PHE B 2 275 ? -34.962 -1.892 -62.834 1.00 60.66 ? 275 PHE C CE1 1 +ATOM 4430 C CE2 . PHE B 2 275 ? -34.040 -0.215 -64.269 1.00 57.62 ? 275 PHE C CE2 1 +ATOM 4431 C CZ . PHE B 2 275 ? -35.115 -0.734 -63.576 1.00 59.84 ? 275 PHE C CZ 1 +ATOM 4432 N N . PHE B 2 276 ? -30.896 -5.957 -64.198 1.00 49.94 ? 276 PHE C N 1 +ATOM 4433 C CA . PHE B 2 276 ? -30.061 -6.792 -65.041 1.00 51.49 ? 276 PHE C CA 1 +ATOM 4434 C C . PHE B 2 276 ? -29.485 -5.970 -66.191 1.00 53.47 ? 276 PHE C C 1 +ATOM 4435 O O . PHE B 2 276 ? -29.991 -4.899 -66.537 1.00 54.93 ? 276 PHE C O 1 +ATOM 4436 C CB . PHE B 2 276 ? -30.859 -7.968 -65.599 1.00 51.81 ? 276 PHE C CB 1 +ATOM 4437 C CG . PHE B 2 276 ? -31.062 -9.086 -64.621 1.00 55.34 ? 276 PHE C CG 1 +ATOM 4438 C CD1 . PHE B 2 276 ? -30.014 -9.929 -64.295 1.00 56.43 ? 276 PHE C CD1 1 +ATOM 4439 C CD2 . PHE B 2 276 ? -32.311 -9.333 -64.073 1.00 56.22 ? 276 PHE C CD2 1 +ATOM 4440 C CE1 . PHE B 2 276 ? -30.196 -10.971 -63.409 1.00 63.41 ? 276 PHE C CE1 1 +ATOM 4441 C CE2 . PHE B 2 276 ? -32.501 -10.381 -63.188 1.00 59.98 ? 276 PHE C CE2 1 +ATOM 4442 C CZ . PHE B 2 276 ? -31.441 -11.201 -62.857 1.00 60.94 ? 276 PHE C CZ 1 +ATOM 4443 N N . TYR B 2 277 ? -28.434 -6.509 -66.818 1.00 54.91 ? 277 TYR C N 1 +ATOM 4444 C CA . TYR B 2 277 ? -27.852 -5.834 -67.974 1.00 48.23 ? 277 TYR C CA 1 +ATOM 4445 C C . TYR B 2 277 ? -28.875 -5.677 -69.091 1.00 43.31 ? 277 TYR C C 1 +ATOM 4446 O O . TYR B 2 277 ? -28.808 -4.713 -69.863 1.00 40.82 ? 277 TYR C O 1 +ATOM 4447 C CB . TYR B 2 277 ? -26.623 -6.600 -68.479 1.00 49.79 ? 277 TYR C CB 1 +ATOM 4448 C CG . TYR B 2 277 ? -26.762 -8.111 -68.421 1.00 63.88 ? 277 TYR C CG 1 +ATOM 4449 C CD1 . TYR B 2 277 ? -27.330 -8.825 -69.472 1.00 55.86 ? 277 TYR C CD1 1 +ATOM 4450 C CD2 . TYR B 2 277 ? -26.335 -8.823 -67.305 1.00 76.45 ? 277 TYR C CD2 1 +ATOM 4451 C CE1 . TYR B 2 277 ? -27.467 -10.206 -69.409 1.00 57.98 ? 277 TYR C CE1 1 +ATOM 4452 C CE2 . TYR B 2 277 ? -26.466 -10.207 -67.236 1.00 78.69 ? 277 TYR C CE2 1 +ATOM 4453 C CZ . TYR B 2 277 ? -27.031 -10.892 -68.292 1.00 71.29 ? 277 TYR C CZ 1 +ATOM 4454 O OH . TYR B 2 277 ? -27.162 -12.265 -68.223 1.00 74.61 ? 277 TYR C OH 1 +ATOM 4455 N N . PHE B 2 278 ? -29.843 -6.585 -69.176 1.00 47.35 ? 278 PHE C N 1 +ATOM 4456 C CA . PHE B 2 278 ? -30.887 -6.485 -70.184 1.00 49.08 ? 278 PHE C CA 1 +ATOM 4457 C C . PHE B 2 278 ? -32.093 -5.690 -69.704 1.00 44.33 ? 278 PHE C C 1 +ATOM 4458 O O . PHE B 2 278 ? -33.142 -5.731 -70.350 1.00 44.38 ? 278 PHE C O 1 +ATOM 4459 C CB . PHE B 2 278 ? -31.315 -7.878 -70.670 1.00 52.82 ? 278 PHE C CB 1 +ATOM 4460 C CG . PHE B 2 278 ? -31.794 -8.809 -69.584 1.00 48.39 ? 278 PHE C CG 1 +ATOM 4461 C CD1 . PHE B 2 278 ? -33.129 -8.833 -69.210 1.00 47.57 ? 278 PHE C CD1 1 +ATOM 4462 C CD2 . PHE B 2 278 ? -30.915 -9.688 -68.967 1.00 46.44 ? 278 PHE C CD2 1 +ATOM 4463 C CE1 . PHE B 2 278 ? -33.577 -9.703 -68.227 1.00 44.75 ? 278 PHE C CE1 1 +ATOM 4464 C CE2 . PHE B 2 278 ? -31.356 -10.555 -67.986 1.00 48.61 ? 278 PHE C CE2 1 +ATOM 4465 C CZ . PHE B 2 278 ? -32.689 -10.562 -67.615 1.00 48.88 ? 278 PHE C CZ 1 +ATOM 4466 N N . SER B 2 279 ? -31.972 -4.982 -68.584 1.00 46.01 ? 279 SER C N 1 +ATOM 4467 C CA . SER B 2 279 ? -33.006 -4.062 -68.138 1.00 50.52 ? 279 SER C CA 1 +ATOM 4468 C C . SER B 2 279 ? -32.517 -2.622 -68.111 1.00 49.48 ? 279 SER C C 1 +ATOM 4469 O O . SER B 2 279 ? -33.319 -1.713 -67.860 1.00 44.83 ? 279 SER C O 1 +ATOM 4470 C CB . SER B 2 279 ? -33.525 -4.461 -66.750 1.00 55.67 ? 279 SER C CB 1 +ATOM 4471 O OG . SER B 2 279 ? -34.104 -5.755 -66.770 1.00 56.28 ? 279 SER C OG 1 +ATOM 4472 N N . ASP B 2 280 ? -31.237 -2.389 -68.393 1.00 49.74 ? 280 ASP C N 1 +ATOM 4473 C CA . ASP B 2 280 ? -30.663 -1.053 -68.337 1.00 50.60 ? 280 ASP C CA 1 +ATOM 4474 C C . ASP B 2 280 ? -31.258 -0.164 -69.424 1.00 54.36 ? 280 ASP C C 1 +ATOM 4475 O O . ASP B 2 280 ? -31.743 -0.637 -70.454 1.00 53.92 ? 280 ASP C O 1 +ATOM 4476 C CB . ASP B 2 280 ? -29.140 -1.132 -68.486 1.00 48.96 ? 280 ASP C CB 1 +ATOM 4477 C CG . ASP B 2 280 ? -28.422 0.058 -67.870 1.00 58.60 ? 280 ASP C CG 1 +ATOM 4478 O OD1 . ASP B 2 280 ? -28.967 1.180 -67.933 1.00 67.27 ? 280 ASP C OD1 1 +ATOM 4479 O OD2 . ASP B 2 280 ? -27.319 -0.133 -67.308 1.00 51.05 ? 280 ASP C OD2 1 +ATOM 4480 N N . PHE B 2 281 ? -31.241 1.139 -69.171 1.00 57.52 ? 281 PHE C N 1 +ATOM 4481 C CA . PHE B 2 281 ? -31.764 2.092 -70.133 1.00 55.10 ? 281 PHE C CA 1 +ATOM 4482 C C . PHE B 2 281 ? -30.751 2.354 -71.236 1.00 61.22 ? 281 PHE C C 1 +ATOM 4483 O O . PHE B 2 281 ? -29.538 2.314 -71.013 1.00 63.29 ? 281 PHE C O 1 +ATOM 4484 C CB . PHE B 2 281 ? -32.125 3.406 -69.446 1.00 55.20 ? 281 PHE C CB 1 +ATOM 4485 C CG . PHE B 2 281 ? -33.278 3.292 -68.498 1.00 57.58 ? 281 PHE C CG 1 +ATOM 4486 C CD1 . PHE B 2 281 ? -34.546 2.991 -68.971 1.00 54.66 ? 281 PHE C CD1 1 +ATOM 4487 C CD2 . PHE B 2 281 ? -33.104 3.502 -67.141 1.00 50.24 ? 281 PHE C CD2 1 +ATOM 4488 C CE1 . PHE B 2 281 ? -35.614 2.891 -68.110 1.00 50.41 ? 281 PHE C CE1 1 +ATOM 4489 C CE2 . PHE B 2 281 ? -34.172 3.400 -66.276 1.00 51.92 ? 281 PHE C CE2 1 +ATOM 4490 C CZ . PHE B 2 281 ? -35.427 3.093 -66.763 1.00 54.82 ? 281 PHE C CZ 1 +ATOM 4491 N N . GLU B 2 282 ? -31.262 2.622 -72.438 1.00 59.14 ? 282 GLU C N 1 +ATOM 4492 C CA . GLU B 2 282 ? -30.443 3.130 -73.534 1.00 53.58 ? 282 GLU C CA 1 +ATOM 4493 C C . GLU B 2 282 ? -30.544 4.648 -73.521 1.00 52.53 ? 282 GLU C C 1 +ATOM 4494 O O . GLU B 2 282 ? -31.621 5.207 -73.750 1.00 55.27 ? 282 GLU C O 1 +ATOM 4495 C CB . GLU B 2 282 ? -30.883 2.554 -74.876 1.00 47.50 ? 282 GLU C CB 1 +ATOM 4496 C CG . GLU B 2 282 ? -30.528 1.096 -75.064 1.00 51.90 ? 282 GLU C CG 1 +ATOM 4497 C CD . GLU B 2 282 ? -30.650 0.653 -76.508 1.00 64.71 ? 282 GLU C CD 1 +ATOM 4498 O OE1 . GLU B 2 282 ? -31.617 1.074 -77.177 1.00 71.56 ? 282 GLU C OE1 1 +ATOM 4499 O OE2 . GLU B 2 282 ? -29.776 -0.111 -76.975 1.00 71.03 ? 282 GLU C OE2 1 +ATOM 4500 N N . ARG B 2 283 ? -29.427 5.315 -73.237 1.00 46.66 ? 283 ARG C N 1 +ATOM 4501 C CA . ARG B 2 283 ? -29.411 6.758 -73.060 1.00 52.83 ? 283 ARG C CA 1 +ATOM 4502 C C . ARG B 2 283 ? -28.538 7.419 -74.120 1.00 61.04 ? 283 ARG C C 1 +ATOM 4503 O O . ARG B 2 283 ? -27.476 6.901 -74.489 1.00 56.80 ? 283 ARG C O 1 +ATOM 4504 C CB . ARG B 2 283 ? -28.916 7.136 -71.659 1.00 54.89 ? 283 ARG C CB 1 +ATOM 4505 C CG . ARG B 2 283 ? -27.459 6.795 -71.381 1.00 61.58 ? 283 ARG C CG 1 +ATOM 4506 C CD . ARG B 2 283 ? -27.277 6.303 -69.955 1.00 64.12 ? 283 ARG C CD 1 +ATOM 4507 N NE . ARG B 2 283 ? -27.121 4.854 -69.888 1.00 58.43 ? 283 ARG C NE 1 +ATOM 4508 C CZ . ARG B 2 283 ? -27.358 4.131 -68.801 1.00 56.72 ? 283 ARG C CZ 1 +ATOM 4509 N NH1 . ARG B 2 283 ? -27.780 4.722 -67.694 1.00 66.95 ? 283 ARG C NH1 1 +ATOM 4510 N NH2 . ARG B 2 283 ? -27.183 2.819 -68.823 1.00 55.91 ? 283 ARG C NH2 1 +ATOM 4511 N N . HIS B 2 284 ? -28.998 8.588 -74.580 1.00 65.28 ? 284 HIS C N 1 +ATOM 4512 C CA . HIS B 2 284 ? -28.274 9.378 -75.573 1.00 62.69 ? 284 HIS C CA 1 +ATOM 4513 C C . HIS B 2 284 ? -26.886 9.781 -75.085 1.00 54.25 ? 284 HIS C C 1 +ATOM 4514 O O . HIS B 2 284 ? -25.975 9.975 -75.899 1.00 47.89 ? 284 HIS C O 1 +ATOM 4515 C CB . HIS B 2 284 ? -29.103 10.612 -75.936 1.00 57.57 ? 284 HIS C CB 1 +ATOM 4516 C CG . HIS B 2 284 ? -29.324 11.550 -74.792 1.00 53.02 ? 284 HIS C CG 1 +ATOM 4517 N ND1 . HIS B 2 284 ? -29.548 11.116 -73.503 1.00 56.09 ? 284 HIS C ND1 1 +ATOM 4518 C CD2 . HIS B 2 284 ? -29.337 12.902 -74.741 1.00 56.99 ? 284 HIS C CD2 1 +ATOM 4519 C CE1 . HIS B 2 284 ? -29.691 12.160 -72.707 1.00 62.32 ? 284 HIS C CE1 1 +ATOM 4520 N NE2 . HIS B 2 284 ? -29.568 13.256 -73.434 1.00 64.21 ? 284 HIS C NE2 1 +ATOM 4521 N N . ASN B 2 285 ? -26.717 9.933 -73.769 1.00 54.12 ? 285 ASN C N 1 +ATOM 4522 C CA . ASN B 2 285 ? -25.407 10.218 -73.196 1.00 52.06 ? 285 ASN C CA 1 +ATOM 4523 C C . ASN B 2 285 ? -24.370 9.231 -73.707 1.00 57.62 ? 285 ASN C C 1 +ATOM 4524 O O . ASN B 2 285 ? -23.299 9.618 -74.188 1.00 54.63 ? 285 ASN C O 1 +ATOM 4525 C CB . ASN B 2 285 ? -25.477 10.129 -71.669 1.00 54.81 ? 285 ASN C CB 1 +ATOM 4526 C CG . ASN B 2 285 ? -26.698 10.809 -71.100 1.00 63.74 ? 285 ASN C CG 1 +ATOM 4527 O OD1 . ASN B 2 285 ? -26.994 11.954 -71.435 1.00 77.45 ? 285 ASN C OD1 1 +ATOM 4528 N ND2 . ASN B 2 285 ? -27.428 10.099 -70.240 1.00 56.73 ? 285 ASN C ND2 1 +ATOM 4529 N N . ALA B 2 286 ? -24.696 7.938 -73.628 1.00 58.55 ? 286 ALA C N 1 +ATOM 4530 C CA . ALA B 2 286 ? -23.730 6.900 -73.959 1.00 57.06 ? 286 ALA C CA 1 +ATOM 4531 C C . ALA B 2 286 ? -23.373 6.924 -75.438 1.00 55.17 ? 286 ALA C C 1 +ATOM 4532 O O . ALA B 2 286 ? -22.192 6.829 -75.796 1.00 49.49 ? 286 ALA C O 1 +ATOM 4533 C CB . ALA B 2 286 ? -24.284 5.533 -73.560 1.00 55.84 ? 286 ALA C CB 1 +ATOM 4534 N N . GLU B 2 287 ? -24.376 7.094 -76.306 1.00 54.66 ? 287 GLU C N 1 +ATOM 4535 C CA . GLU B 2 287 ? -24.135 7.067 -77.747 1.00 55.84 ? 287 GLU C CA 1 +ATOM 4536 C C . GLU B 2 287 ? -23.116 8.122 -78.150 1.00 53.06 ? 287 GLU C C 1 +ATOM 4537 O O . GLU B 2 287 ? -22.129 7.822 -78.831 1.00 48.23 ? 287 GLU C O 1 +ATOM 4538 C CB . GLU B 2 287 ? -25.452 7.278 -78.494 1.00 59.58 ? 287 GLU C CB 1 +ATOM 4539 C CG . GLU B 2 287 ? -26.451 6.143 -78.340 1.00 59.08 ? 287 GLU C CG 1 +ATOM 4540 C CD . GLU B 2 287 ? -26.086 4.922 -79.166 1.00 60.69 ? 287 GLU C CD 1 +ATOM 4541 O OE1 . GLU B 2 287 ? -25.158 5.011 -80.001 1.00 57.26 ? 287 GLU C OE1 1 +ATOM 4542 O OE2 . GLU B 2 287 ? -26.728 3.868 -78.977 1.00 64.34 ? 287 GLU C OE2 1 +ATOM 4543 N N . ILE B 2 288 ? -23.330 9.362 -77.709 1.00 55.82 ? 288 ILE C N 1 +ATOM 4544 C CA . ILE B 2 288 ? -22.412 10.450 -78.025 1.00 48.98 ? 288 ILE C CA 1 +ATOM 4545 C C . ILE B 2 288 ? -21.062 10.217 -77.363 1.00 50.21 ? 288 ILE C C 1 +ATOM 4546 O O . ILE B 2 288 ? -20.008 10.413 -77.980 1.00 49.44 ? 288 ILE C O 1 +ATOM 4547 C CB . ILE B 2 288 ? -23.021 11.789 -77.582 1.00 47.36 ? 288 ILE C CB 1 +ATOM 4548 C CG1 . ILE B 2 288 ? -24.465 11.900 -78.065 1.00 49.33 ? 288 ILE C CG1 1 +ATOM 4549 C CG2 . ILE B 2 288 ? -22.190 12.939 -78.111 1.00 50.12 ? 288 ILE C CG2 1 +ATOM 4550 C CD1 . ILE B 2 288 ? -25.223 13.048 -77.442 1.00 46.52 ? 288 ILE C CD1 1 +ATOM 4551 N N . ALA B 2 289 ? -21.072 9.796 -76.097 1.00 48.55 ? 289 ALA C N 1 +ATOM 4552 C CA . ALA B 2 289 ? -19.820 9.574 -75.388 1.00 50.26 ? 289 ALA C CA 1 +ATOM 4553 C C . ALA B 2 289 ? -19.015 8.461 -76.035 1.00 48.39 ? 289 ALA C C 1 +ATOM 4554 O O . ALA B 2 289 ? -17.783 8.536 -76.111 1.00 48.27 ? 289 ALA C O 1 +ATOM 4555 C CB . ALA B 2 289 ? -20.103 9.239 -73.925 1.00 53.36 ? 289 ALA C CB 1 +ATOM 4556 N N . ALA B 2 290 ? -19.701 7.434 -76.538 1.00 47.32 ? 290 ALA C N 1 +ATOM 4557 C CA . ALA B 2 290 ? -19.001 6.314 -77.151 1.00 51.34 ? 290 ALA C CA 1 +ATOM 4558 C C . ALA B 2 290 ? -18.220 6.758 -78.376 1.00 50.91 ? 290 ALA C C 1 +ATOM 4559 O O . ALA B 2 290 ? -17.098 6.293 -78.609 1.00 49.36 ? 290 ALA C O 1 +ATOM 4560 C CB . ALA B 2 290 ? -19.995 5.217 -77.528 1.00 54.89 ? 290 ALA C CB 1 +ATOM 4561 N N . PHE B 2 291 ? -18.782 7.687 -79.150 1.00 53.26 ? 291 PHE C N 1 +ATOM 4562 C CA . PHE B 2 291 ? -18.123 8.113 -80.377 1.00 54.56 ? 291 PHE C CA 1 +ATOM 4563 C C . PHE B 2 291 ? -16.800 8.804 -80.075 1.00 55.17 ? 291 PHE C C 1 +ATOM 4564 O O . PHE B 2 291 ? -15.769 8.481 -80.678 1.00 52.19 ? 291 PHE C O 1 +ATOM 4565 C CB . PHE B 2 291 ? -19.047 9.027 -81.181 1.00 50.36 ? 291 PHE C CB 1 +ATOM 4566 C CG . PHE B 2 291 ? -18.366 9.696 -82.328 1.00 55.71 ? 291 PHE C CG 1 +ATOM 4567 C CD1 . PHE B 2 291 ? -17.941 8.956 -83.419 1.00 61.60 ? 291 PHE C CD1 1 +ATOM 4568 C CD2 . PHE B 2 291 ? -18.139 11.056 -82.318 1.00 59.17 ? 291 PHE C CD2 1 +ATOM 4569 C CE1 . PHE B 2 291 ? -17.301 9.557 -84.479 1.00 59.32 ? 291 PHE C CE1 1 +ATOM 4570 C CE2 . PHE B 2 291 ? -17.499 11.669 -83.378 1.00 67.91 ? 291 PHE C CE2 1 +ATOM 4571 C CZ . PHE B 2 291 ? -17.080 10.917 -84.461 1.00 67.49 ? 291 PHE C CZ 1 +ATOM 4572 N N . HIS B 2 292 ? -16.802 9.732 -79.117 1.00 57.20 ? 292 HIS C N 1 +ATOM 4573 C CA . HIS B 2 292 ? -15.565 10.416 -78.757 1.00 56.97 ? 292 HIS C CA 1 +ATOM 4574 C C . HIS B 2 292 ? -14.588 9.464 -78.080 1.00 59.49 ? 292 HIS C C 1 +ATOM 4575 O O . HIS B 2 292 ? -13.379 9.532 -78.324 1.00 57.48 ? 292 HIS C O 1 +ATOM 4576 C CB . HIS B 2 292 ? -15.873 11.611 -77.855 1.00 52.50 ? 292 HIS C CB 1 +ATOM 4577 C CG . HIS B 2 292 ? -16.578 12.730 -78.555 1.00 52.21 ? 292 HIS C CG 1 +ATOM 4578 N ND1 . HIS B 2 292 ? -15.902 13.724 -79.229 1.00 56.17 ? 292 HIS C ND1 1 +ATOM 4579 C CD2 . HIS B 2 292 ? -17.896 13.010 -78.693 1.00 53.70 ? 292 HIS C CD2 1 +ATOM 4580 C CE1 . HIS B 2 292 ? -16.774 14.570 -79.750 1.00 59.37 ? 292 HIS C CE1 1 +ATOM 4581 N NE2 . HIS B 2 292 ? -17.991 14.161 -79.437 1.00 51.01 ? 292 HIS C NE2 1 +ATOM 4582 N N . LEU B 2 293 ? -15.098 8.562 -77.236 1.00 62.03 ? 293 LEU C N 1 +ATOM 4583 C CA . LEU B 2 293 ? -14.250 7.549 -76.611 1.00 63.58 ? 293 LEU C CA 1 +ATOM 4584 C C . LEU B 2 293 ? -13.566 6.692 -77.669 1.00 60.82 ? 293 LEU C C 1 +ATOM 4585 O O . LEU B 2 293 ? -12.359 6.426 -77.596 1.00 53.69 ? 293 LEU C O 1 +ATOM 4586 C CB . LEU B 2 293 ? -15.095 6.681 -75.673 1.00 61.87 ? 293 LEU C CB 1 +ATOM 4587 C CG . LEU B 2 293 ? -14.447 5.862 -74.547 1.00 59.62 ? 293 LEU C CG 1 +ATOM 4588 C CD1 . LEU B 2 293 ? -13.529 4.767 -75.062 1.00 57.37 ? 293 LEU C CD1 1 +ATOM 4589 C CD2 . LEU B 2 293 ? -13.704 6.759 -73.586 1.00 60.01 ? 293 LEU C CD2 1 +ATOM 4590 N N . ASP B 2 294 ? -14.343 6.223 -78.646 1.00 58.94 ? 294 ASP C N 1 +ATOM 4591 C CA . ASP B 2 294 ? -13.789 5.428 -79.732 1.00 57.40 ? 294 ASP C CA 1 +ATOM 4592 C C . ASP B 2 294 ? -12.846 6.258 -80.595 1.00 55.87 ? 294 ASP C C 1 +ATOM 4593 O O . ASP B 2 294 ? -11.801 5.766 -81.036 1.00 55.08 ? 294 ASP C O 1 +ATOM 4594 C CB . ASP B 2 294 ? -14.939 4.842 -80.549 1.00 52.90 ? 294 ASP C CB 1 +ATOM 4595 C CG . ASP B 2 294 ? -14.481 4.180 -81.822 1.00 55.45 ? 294 ASP C CG 1 +ATOM 4596 O OD1 . ASP B 2 294 ? -14.173 4.902 -82.795 1.00 56.51 ? 294 ASP C OD1 1 +ATOM 4597 O OD2 . ASP B 2 294 ? -14.427 2.933 -81.843 1.00 51.54 ? 294 ASP C OD2 1 +ATOM 4598 N N . ARG B 2 295 ? -13.187 7.526 -80.828 1.00 57.38 ? 295 ARG C N 1 +ATOM 4599 C CA . ARG B 2 295 ? -12.305 8.400 -81.593 1.00 62.58 ? 295 ARG C CA 1 +ATOM 4600 C C . ARG B 2 295 ? -10.993 8.638 -80.860 1.00 60.68 ? 295 ARG C C 1 +ATOM 4601 O O . ARG B 2 295 ? -9.919 8.624 -81.475 1.00 54.46 ? 295 ARG C O 1 +ATOM 4602 C CB . ARG B 2 295 ? -13.005 9.731 -81.864 1.00 70.33 ? 295 ARG C CB 1 +ATOM 4603 C CG . ARG B 2 295 ? -12.087 10.852 -82.331 1.00 67.06 ? 295 ARG C CG 1 +ATOM 4604 C CD . ARG B 2 295 ? -12.776 12.195 -82.181 1.00 64.00 ? 295 ARG C CD 1 +ATOM 4605 N NE . ARG B 2 295 ? -13.463 12.579 -83.407 1.00 58.74 ? 295 ARG C NE 1 +ATOM 4606 C CZ . ARG B 2 295 ? -14.370 13.545 -83.477 1.00 61.36 ? 295 ARG C CZ 1 +ATOM 4607 N NH1 . ARG B 2 295 ? -14.705 14.219 -82.384 1.00 59.73 ? 295 ARG C NH1 1 +ATOM 4608 N NH2 . ARG B 2 295 ? -14.945 13.835 -84.636 1.00 62.66 ? 295 ARG C NH2 1 +ATOM 4609 N N . ILE B 2 296 ? -11.066 8.831 -79.539 1.00 60.62 ? 296 ILE C N 1 +ATOM 4610 C CA . ILE B 2 296 ? -9.886 9.145 -78.738 1.00 59.96 ? 296 ILE C CA 1 +ATOM 4611 C C . ILE B 2 296 ? -8.922 7.966 -78.712 1.00 63.80 ? 296 ILE C C 1 +ATOM 4612 O O . ILE B 2 296 ? -7.697 8.155 -78.712 1.00 60.43 ? 296 ILE C O 1 +ATOM 4613 C CB . ILE B 2 296 ? -10.316 9.569 -77.320 1.00 56.43 ? 296 ILE C CB 1 +ATOM 4614 C CG1 . ILE B 2 296 ? -10.382 11.094 -77.198 1.00 54.05 ? 296 ILE C CG1 1 +ATOM 4615 C CG2 . ILE B 2 296 ? -9.369 9.014 -76.267 1.00 64.11 ? 296 ILE C CG2 1 +ATOM 4616 C CD1 . ILE B 2 296 ? -11.307 11.765 -78.185 1.00 55.16 ? 296 ILE C CD1 1 +ATOM 4617 N N . LEU B 2 297 ? -9.446 6.740 -78.712 1.00 59.76 ? 297 LEU C N 1 +ATOM 4618 C CA . LEU B 2 297 ? -8.611 5.549 -78.767 1.00 57.96 ? 297 LEU C CA 1 +ATOM 4619 C C . LEU B 2 297 ? -8.131 5.245 -80.175 1.00 57.82 ? 297 LEU C C 1 +ATOM 4620 O O . LEU B 2 297 ? -7.391 4.271 -80.367 1.00 50.55 ? 297 LEU C O 1 +ATOM 4621 C CB . LEU B 2 297 ? -9.382 4.343 -78.225 1.00 51.72 ? 297 LEU C CB 1 +ATOM 4622 C CG . LEU B 2 297 ? -10.000 4.478 -76.837 1.00 48.94 ? 297 LEU C CG 1 +ATOM 4623 C CD1 . LEU B 2 297 ? -10.721 3.203 -76.474 1.00 51.86 ? 297 LEU C CD1 1 +ATOM 4624 C CD2 . LEU B 2 297 ? -8.927 4.792 -75.815 1.00 58.55 ? 297 LEU C CD2 1 +ATOM 4625 N N . ASP B 2 298 ? -8.500 6.087 -81.143 1.00 62.14 ? 298 ASP C N 1 +ATOM 4626 C CA . ASP B 2 298 ? -8.120 5.927 -82.543 1.00 62.35 ? 298 ASP C CA 1 +ATOM 4627 C C . ASP B 2 298 ? -8.578 4.584 -83.114 1.00 60.19 ? 298 ASP C C 1 +ATOM 4628 O O . ASP B 2 298 ? -7.928 4.017 -83.997 1.00 59.45 ? 298 ASP C O 1 +ATOM 4629 C CB . ASP B 2 298 ? -6.611 6.110 -82.720 1.00 62.28 ? 298 ASP C CB 1 +ATOM 4630 C CG . ASP B 2 298 ? -6.250 6.683 -84.066 1.00 60.30 ? 298 ASP C CG 1 +ATOM 4631 O OD1 . ASP B 2 298 ? -6.542 7.872 -84.318 1.00 57.56 ? 298 ASP C OD1 1 +ATOM 4632 O OD2 . ASP B 2 298 ? -5.688 5.927 -84.877 1.00 64.03 ? 298 ASP C OD2 1 +ATOM 4633 N N . PHE B 2 299 ? -9.711 4.075 -82.621 1.00 56.79 ? 299 PHE C N 1 +ATOM 4634 C CA . PHE B 2 299 ? -10.297 2.858 -83.173 1.00 53.29 ? 299 PHE C CA 1 +ATOM 4635 C C . PHE B 2 299 ? -11.072 3.158 -84.447 1.00 53.94 ? 299 PHE C C 1 +ATOM 4636 O O . PHE B 2 299 ? -10.896 2.477 -85.465 1.00 54.37 ? 299 PHE C O 1 +ATOM 4637 C CB . PHE B 2 299 ? -11.221 2.194 -82.145 1.00 53.24 ? 299 PHE C CB 1 +ATOM 4638 C CG . PHE B 2 299 ? -10.502 1.378 -81.114 1.00 50.39 ? 299 PHE C CG 1 +ATOM 4639 C CD1 . PHE B 2 299 ? -9.296 0.770 -81.411 1.00 52.52 ? 299 PHE C CD1 1 +ATOM 4640 C CD2 . PHE B 2 299 ? -11.033 1.222 -79.845 1.00 44.71 ? 299 PHE C CD2 1 +ATOM 4641 C CE1 . PHE B 2 299 ? -8.633 0.021 -80.462 1.00 52.48 ? 299 PHE C CE1 1 +ATOM 4642 C CE2 . PHE B 2 299 ? -10.374 0.475 -78.892 1.00 46.70 ? 299 PHE C CE2 1 +ATOM 4643 C CZ . PHE B 2 299 ? -9.171 -0.127 -79.200 1.00 49.81 ? 299 PHE C CZ 1 +ATOM 4644 N N . ARG B 2 300 ? -11.930 4.181 -84.397 1.00 54.47 ? 300 ARG C N 1 +ATOM 4645 C CA . ARG B 2 300 ? -12.744 4.619 -85.531 1.00 56.46 ? 300 ARG C CA 1 +ATOM 4646 C C . ARG B 2 300 ? -13.620 3.475 -86.051 1.00 52.27 ? 300 ARG C C 1 +ATOM 4647 O O . ARG B 2 300 ? -13.593 3.108 -87.226 1.00 54.44 ? 300 ARG C O 1 +ATOM 4648 C CB . ARG B 2 300 ? -11.856 5.215 -86.632 1.00 57.90 ? 300 ARG C CB 1 +ATOM 4649 C CG . ARG B 2 300 ? -11.230 6.554 -86.246 1.00 52.35 ? 300 ARG C CG 1 +ATOM 4650 C CD . ARG B 2 300 ? -9.930 6.822 -86.987 1.00 53.22 ? 300 ARG C CD 1 +ATOM 4651 N NE . ARG B 2 300 ? -9.018 5.682 -86.915 1.00 55.65 ? 300 ARG C NE 1 +ATOM 4652 C CZ . ARG B 2 300 ? -7.940 5.529 -87.680 1.00 57.85 ? 300 ARG C CZ 1 +ATOM 4653 N NH1 . ARG B 2 300 ? -7.634 6.446 -88.585 1.00 60.48 ? 300 ARG C NH1 1 +ATOM 4654 N NH2 . ARG B 2 300 ? -7.172 4.455 -87.546 1.00 53.68 ? 300 ARG C NH2 1 +ATOM 4655 N N . ARG B 2 301 ? -14.400 2.907 -85.135 1.00 47.85 ? 301 ARG C N 1 +ATOM 4656 C CA . ARG B 2 301 ? -15.328 1.836 -85.458 1.00 46.08 ? 301 ARG C CA 1 +ATOM 4657 C C . ARG B 2 301 ? -16.771 2.207 -85.172 1.00 46.59 ? 301 ARG C C 1 +ATOM 4658 O O . ARG B 2 301 ? -17.649 1.353 -85.325 1.00 50.11 ? 301 ARG C O 1 +ATOM 4659 C CB . ARG B 2 301 ? -14.996 0.560 -84.670 1.00 51.34 ? 301 ARG C CB 1 +ATOM 4660 C CG . ARG B 2 301 ? -13.537 0.368 -84.287 1.00 57.60 ? 301 ARG C CG 1 +ATOM 4661 C CD . ARG B 2 301 ? -12.752 -0.372 -85.349 1.00 53.39 ? 301 ARG C CD 1 +ATOM 4662 N NE . ARG B 2 301 ? -11.362 -0.573 -84.948 1.00 55.89 ? 301 ARG C NE 1 +ATOM 4663 C CZ . ARG B 2 301 ? -10.954 -1.528 -84.117 1.00 56.68 ? 301 ARG C CZ 1 +ATOM 4664 N NH1 . ARG B 2 301 ? -11.829 -2.373 -83.583 1.00 50.02 ? 301 ARG C NH1 1 +ATOM 4665 N NH2 . ARG B 2 301 ? -9.668 -1.634 -83.814 1.00 59.94 ? 301 ARG C NH2 1 +ATOM 4666 N N . VAL B 2 302 ? -17.044 3.431 -84.730 1.00 48.17 ? 302 VAL C N 1 +ATOM 4667 C CA . VAL B 2 302 ? -18.404 3.828 -84.369 1.00 49.36 ? 302 VAL C CA 1 +ATOM 4668 C C . VAL B 2 302 ? -18.910 4.824 -85.402 1.00 52.43 ? 302 VAL C C 1 +ATOM 4669 O O . VAL B 2 302 ? -18.121 5.620 -85.929 1.00 56.93 ? 302 VAL C O 1 +ATOM 4670 C CB . VAL B 2 302 ? -18.471 4.440 -82.961 1.00 41.49 ? 302 VAL C CB 1 +ATOM 4671 C CG1 . VAL B 2 302 ? -18.165 3.400 -81.910 1.00 41.91 ? 302 VAL C CG1 1 +ATOM 4672 C CG2 . VAL B 2 302 ? -17.504 5.593 -82.856 1.00 48.39 ? 302 VAL C CG2 1 +ATOM 4673 N N . PRO B 2 303 ? -20.196 4.811 -85.732 1.00 47.01 ? 303 PRO C N 1 +ATOM 4674 C CA . PRO B 2 303 ? -20.741 5.857 -86.581 1.00 48.67 ? 303 PRO C CA 1 +ATOM 4675 C C . PRO B 2 303 ? -20.815 7.168 -85.819 1.00 53.59 ? 303 PRO C C 1 +ATOM 4676 O O . PRO B 2 303 ? -21.134 7.182 -84.619 1.00 52.88 ? 303 PRO C O 1 +ATOM 4677 C CB . PRO B 2 303 ? -22.139 5.329 -86.935 1.00 42.90 ? 303 PRO C CB 1 +ATOM 4678 C CG . PRO B 2 303 ? -22.502 4.470 -85.792 1.00 40.23 ? 303 PRO C CG 1 +ATOM 4679 C CD . PRO B 2 303 ? -21.222 3.834 -85.333 1.00 46.58 ? 303 PRO C CD 1 +ATOM 4680 N N . PRO B 2 304 ? -20.498 8.286 -86.472 1.00 50.57 ? 304 PRO C N 1 +ATOM 4681 C CA . PRO B 2 304 ? -20.541 9.580 -85.786 1.00 48.96 ? 304 PRO C CA 1 +ATOM 4682 C C . PRO B 2 304 ? -21.938 9.888 -85.279 1.00 52.14 ? 304 PRO C C 1 +ATOM 4683 O O . PRO B 2 304 ? -22.936 9.670 -85.969 1.00 51.93 ? 304 PRO C O 1 +ATOM 4684 C CB . PRO B 2 304 ? -20.108 10.569 -86.872 1.00 50.98 ? 304 PRO C CB 1 +ATOM 4685 C CG . PRO B 2 304 ? -19.334 9.750 -87.842 1.00 50.21 ? 304 PRO C CG 1 +ATOM 4686 C CD . PRO B 2 304 ? -19.997 8.412 -87.850 1.00 49.70 ? 304 PRO C CD 1 +ATOM 4687 N N . VAL B 2 305 ? -22.000 10.408 -84.061 1.00 52.12 ? 305 VAL C N 1 +ATOM 4688 C CA . VAL B 2 305 ? -23.263 10.751 -83.425 1.00 51.66 ? 305 VAL C CA 1 +ATOM 4689 C C . VAL B 2 305 ? -23.089 12.093 -82.726 1.00 52.89 ? 305 VAL C C 1 +ATOM 4690 O O . VAL B 2 305 ? -22.021 12.385 -82.177 1.00 51.21 ? 305 VAL C O 1 +ATOM 4691 C CB . VAL B 2 305 ? -23.713 9.634 -82.455 1.00 49.43 ? 305 VAL C CB 1 +ATOM 4692 C CG1 . VAL B 2 305 ? -22.580 9.261 -81.531 1.00 53.29 ? 305 VAL C CG1 1 +ATOM 4693 C CG2 . VAL B 2 305 ? -24.961 10.035 -81.668 1.00 49.24 ? 305 VAL C CG2 1 +ATOM 4694 N N . ALA B 2 306 ? -24.113 12.939 -82.814 1.00 48.53 ? 306 ALA C N 1 +ATOM 4695 C CA . ALA B 2 306 ? -24.108 14.250 -82.186 1.00 47.19 ? 306 ALA C CA 1 +ATOM 4696 C C . ALA B 2 306 ? -25.457 14.488 -81.525 1.00 49.04 ? 306 ALA C C 1 +ATOM 4697 O O . ALA B 2 306 ? -26.486 13.999 -81.997 1.00 47.24 ? 306 ALA C O 1 +ATOM 4698 C CB . ALA B 2 306 ? -23.800 15.355 -83.202 1.00 55.60 ? 306 ALA C CB 1 +ATOM 4699 N N . GLY B 2 307 ? -25.445 15.246 -80.433 1.00 48.35 ? 307 GLY C N 1 +ATOM 4700 C CA . GLY B 2 307 ? -26.645 15.507 -79.645 1.00 53.45 ? 307 GLY C CA 1 +ATOM 4701 C C . GLY B 2 307 ? -27.322 16.803 -80.053 1.00 51.26 ? 307 GLY C C 1 +ATOM 4702 O O . GLY B 2 307 ? -26.658 17.771 -80.412 1.00 50.77 ? 307 GLY C O 1 +ATOM 4703 N N . ARG B 2 308 ? -28.649 16.811 -79.990 1.00 49.30 ? 308 ARG C N 1 +ATOM 4704 C CA . ARG B 2 308 ? -29.431 17.942 -80.466 1.00 53.11 ? 308 ARG C CA 1 +ATOM 4705 C C . ARG B 2 308 ? -30.665 18.153 -79.594 1.00 59.43 ? 308 ARG C C 1 +ATOM 4706 O O . ARG B 2 308 ? -31.351 17.193 -79.235 1.00 64.60 ? 308 ARG C O 1 +ATOM 4707 C CB . ARG B 2 308 ? -29.827 17.716 -81.927 1.00 54.76 ? 308 ARG C CB 1 +ATOM 4708 C CG . ARG B 2 308 ? -30.686 18.797 -82.529 1.00 58.62 ? 308 ARG C CG 1 +ATOM 4709 C CD . ARG B 2 308 ? -30.982 18.483 -83.975 1.00 51.84 ? 308 ARG C CD 1 +ATOM 4710 N NE . ARG B 2 308 ? -31.932 19.425 -84.551 1.00 57.84 ? 308 ARG C NE 1 +ATOM 4711 C CZ . ARG B 2 308 ? -32.120 19.585 -85.855 1.00 60.07 ? 308 ARG C CZ 1 +ATOM 4712 N NH1 . ARG B 2 308 ? -31.408 18.871 -86.718 1.00 57.55 ? 308 ARG C NH1 1 +ATOM 4713 N NH2 . ARG B 2 308 ? -33.014 20.462 -86.296 1.00 63.69 ? 308 ARG C NH2 1 +ATOM 4714 N N . LEU B 2 309 ? -30.955 19.417 -79.275 1.00 60.76 ? 309 LEU C N 1 +ATOM 4715 C CA . LEU B 2 309 ? -32.170 19.803 -78.550 1.00 61.27 ? 309 LEU C CA 1 +ATOM 4716 C C . LEU B 2 309 ? -33.312 19.929 -79.551 1.00 64.03 ? 309 LEU C C 1 +ATOM 4717 O O . LEU B 2 309 ? -33.442 20.949 -80.232 1.00 77.86 ? 309 LEU C O 1 +ATOM 4718 C CB . LEU B 2 309 ? -31.962 21.123 -77.815 1.00 69.25 ? 309 LEU C CB 1 +ATOM 4719 C CG . LEU B 2 309 ? -30.892 21.189 -76.725 1.00 73.99 ? 309 LEU C CG 1 +ATOM 4720 C CD1 . LEU B 2 309 ? -30.659 22.619 -76.232 1.00 65.62 ? 309 LEU C CD1 1 +ATOM 4721 C CD2 . LEU B 2 309 ? -31.293 20.290 -75.575 1.00 80.90 ? 309 LEU C CD2 1 +ATOM 4722 N N . VAL B 2 310 ? -34.149 18.905 -79.656 1.00 54.71 ? 310 VAL C N 1 +ATOM 4723 C CA . VAL B 2 310 ? -35.190 18.898 -80.678 1.00 54.30 ? 310 VAL C CA 1 +ATOM 4724 C C . VAL B 2 310 ? -36.515 19.364 -80.084 1.00 51.02 ? 310 VAL C C 1 +ATOM 4725 O O . VAL B 2 310 ? -36.790 19.186 -78.893 1.00 53.57 ? 310 VAL C O 1 +ATOM 4726 C CB . VAL B 2 310 ? -35.317 17.506 -81.332 1.00 50.02 ? 310 VAL C CB 1 +ATOM 4727 C CG1 . VAL B 2 310 ? -33.956 17.036 -81.840 1.00 47.45 ? 310 VAL C CG1 1 +ATOM 4728 C CG2 . VAL B 2 310 ? -35.899 16.514 -80.362 1.00 58.32 ? 310 VAL C CG2 1 +ATOM 4729 N N . ASN B 2 311 ? -37.333 19.996 -80.931 1.00 49.38 ? 311 ASN C N 1 +ATOM 4730 C CA . ASN B 2 311 ? -38.681 20.444 -80.585 1.00 49.84 ? 311 ASN C CA 1 +ATOM 4731 C C . ASN B 2 311 ? -39.665 19.326 -80.902 1.00 48.40 ? 311 ASN C C 1 +ATOM 4732 O O . ASN B 2 311 ? -39.849 18.973 -82.071 1.00 52.25 ? 311 ASN C O 1 +ATOM 4733 C CB . ASN B 2 311 ? -39.027 21.717 -81.372 1.00 58.74 ? 311 ASN C CB 1 +ATOM 4734 C CG . ASN B 2 311 ? -40.405 22.306 -81.025 1.00 58.70 ? 311 ASN C CG 1 +ATOM 4735 O OD1 . ASN B 2 311 ? -41.362 21.574 -80.769 1.00 60.50 ? 311 ASN C OD1 1 +ATOM 4736 N ND2 . ASN B 2 311 ? -40.511 23.639 -81.056 1.00 47.83 ? 311 ASN C ND2 1 +ATOM 4737 N N . MET B 2 312 ? -40.336 18.810 -79.875 1.00 46.93 ? 312 MET C N 1 +ATOM 4738 C CA . MET B 2 312 ? -41.246 17.691 -80.092 1.00 53.24 ? 312 MET C CA 1 +ATOM 4739 C C . MET B 2 312 ? -42.538 18.090 -80.786 1.00 53.54 ? 312 MET C C 1 +ATOM 4740 O O . MET B 2 312 ? -43.350 17.212 -81.100 1.00 54.60 ? 312 MET C O 1 +ATOM 4741 C CB . MET B 2 312 ? -41.556 17.000 -78.763 1.00 58.38 ? 312 MET C CB 1 +ATOM 4742 C CG . MET B 2 312 ? -41.664 17.934 -77.573 1.00 67.54 ? 312 MET C CG 1 +ATOM 4743 S SD . MET B 2 312 ? -42.438 17.181 -76.124 1.00 83.67 ? 312 MET C SD 1 +ATOM 4744 C CE . MET B 2 312 ? -41.762 15.529 -76.159 1.00 65.10 ? 312 MET C CE 1 +ATOM 4745 N N . THR B 2 313 ? -42.757 19.373 -81.049 1.00 53.85 ? 313 THR C N 1 +ATOM 4746 C CA . THR B 2 313 ? -43.946 19.775 -81.790 1.00 65.23 ? 313 THR C CA 1 +ATOM 4747 C C . THR B 2 313 ? -43.676 19.812 -83.292 1.00 68.26 ? 313 THR C C 1 +ATOM 4748 O O . THR B 2 313 ? -44.318 19.093 -84.061 1.00 63.73 ? 313 THR C O 1 +ATOM 4749 C CB . THR B 2 313 ? -44.446 21.129 -81.281 1.00 74.46 ? 313 THR C CB 1 +ATOM 4750 O OG1 . THR B 2 313 ? -44.958 20.973 -79.949 1.00 67.09 ? 313 THR C OG1 1 +ATOM 4751 C CG2 . THR B 2 313 ? -45.531 21.686 -82.200 1.00 76.60 ? 313 THR C CG2 1 +ATOM 4752 N N . ARG B 2 314 ? -42.712 20.626 -83.719 1.00 68.41 ? 314 ARG C N 1 +ATOM 4753 C CA . ARG B 2 314 ? -42.453 20.806 -85.140 1.00 63.64 ? 314 ARG C CA 1 +ATOM 4754 C C . ARG B 2 314 ? -41.408 19.847 -85.694 1.00 65.16 ? 314 ARG C C 1 +ATOM 4755 O O . ARG B 2 314 ? -41.376 19.635 -86.912 1.00 73.80 ? 314 ARG C O 1 +ATOM 4756 C CB . ARG B 2 314 ? -42.010 22.248 -85.415 1.00 65.02 ? 314 ARG C CB 1 +ATOM 4757 C CG . ARG B 2 314 ? -40.669 22.621 -84.805 1.00 54.40 ? 314 ARG C CG 1 +ATOM 4758 C CD . ARG B 2 314 ? -40.258 24.026 -85.195 1.00 47.23 ? 314 ARG C CD 1 +ATOM 4759 N NE . ARG B 2 314 ? -38.938 24.352 -84.667 1.00 55.92 ? 314 ARG C NE 1 +ATOM 4760 C CZ . ARG B 2 314 ? -37.795 24.078 -85.287 1.00 59.81 ? 314 ARG C CZ 1 +ATOM 4761 N NH1 . ARG B 2 314 ? -36.636 24.407 -84.728 1.00 59.63 ? 314 ARG C NH1 1 +ATOM 4762 N NH2 . ARG B 2 314 ? -37.811 23.480 -86.470 1.00 54.98 ? 314 ARG C NH2 1 +ATOM 4763 N N . GLU B 2 315 ? -40.571 19.242 -84.846 1.00 54.95 ? 315 GLU C N 1 +ATOM 4764 C CA . GLU B 2 315 ? -39.547 18.324 -85.331 1.00 55.01 ? 315 GLU C CA 1 +ATOM 4765 C C . GLU B 2 315 ? -39.854 16.852 -85.078 1.00 55.99 ? 315 GLU C C 1 +ATOM 4766 O O . GLU B 2 315 ? -39.129 15.995 -85.596 1.00 50.73 ? 315 GLU C O 1 +ATOM 4767 C CB . GLU B 2 315 ? -38.175 18.661 -84.718 1.00 47.53 ? 315 GLU C CB 1 +ATOM 4768 C CG . GLU B 2 315 ? -37.636 20.039 -85.078 1.00 48.34 ? 315 GLU C CG 1 +ATOM 4769 C CD . GLU B 2 315 ? -36.165 20.200 -84.722 1.00 46.88 ? 315 GLU C CD 1 +ATOM 4770 O OE1 . GLU B 2 315 ? -35.312 19.768 -85.526 1.00 43.44 ? 315 GLU C OE1 1 +ATOM 4771 O OE2 . GLU B 2 315 ? -35.854 20.774 -83.657 1.00 47.63 ? 315 GLU C OE2 1 +ATOM 4772 N N . ILE B 2 316 ? -40.916 16.532 -84.334 1.00 59.99 ? 316 ILE C N 1 +ATOM 4773 C CA . ILE B 2 316 ? -41.285 15.144 -84.060 1.00 52.67 ? 316 ILE C CA 1 +ATOM 4774 C C . ILE B 2 316 ? -42.743 14.904 -84.441 1.00 50.41 ? 316 ILE C C 1 +ATOM 4775 O O . ILE B 2 316 ? -43.036 14.134 -85.360 1.00 52.74 ? 316 ILE C O 1 +ATOM 4776 C CB . ILE B 2 316 ? -41.056 14.772 -82.582 1.00 49.55 ? 316 ILE C CB 1 +ATOM 4777 C CG1 . ILE B 2 316 ? -39.610 15.037 -82.142 1.00 45.56 ? 316 ILE C CG1 1 +ATOM 4778 C CG2 . ILE B 2 316 ? -41.406 13.312 -82.362 1.00 45.31 ? 316 ILE C CG2 1 +ATOM 4779 C CD1 . ILE B 2 316 ? -38.589 14.084 -82.704 1.00 44.09 ? 316 ILE C CD1 1 +ATOM 4780 N N . ARG B 2 317 ? -43.667 15.544 -83.719 1.00 49.95 ? 317 ARG C N 1 +ATOM 4781 C CA . ARG B 2 317 ? -45.087 15.226 -83.861 1.00 55.00 ? 317 ARG C CA 1 +ATOM 4782 C C . ARG B 2 317 ? -45.654 15.694 -85.197 1.00 67.04 ? 317 ARG C C 1 +ATOM 4783 O O . ARG B 2 317 ? -46.355 14.940 -85.883 1.00 65.45 ? 317 ARG C O 1 +ATOM 4784 C CB . ARG B 2 317 ? -45.884 15.848 -82.719 1.00 57.05 ? 317 ARG C CB 1 +ATOM 4785 C CG . ARG B 2 317 ? -47.378 15.577 -82.829 1.00 62.65 ? 317 ARG C CG 1 +ATOM 4786 C CD . ARG B 2 317 ? -48.150 16.388 -81.808 1.00 70.17 ? 317 ARG C CD 1 +ATOM 4787 N NE . ARG B 2 317 ? -48.018 17.825 -82.032 1.00 72.46 ? 317 ARG C NE 1 +ATOM 4788 C CZ . ARG B 2 317 ? -48.469 18.754 -81.195 1.00 71.86 ? 317 ARG C CZ 1 +ATOM 4789 N NH1 . ARG B 2 317 ? -49.079 18.403 -80.070 1.00 72.41 ? 317 ARG C NH1 1 +ATOM 4790 N NH2 . ARG B 2 317 ? -48.305 20.037 -81.480 1.00 72.65 ? 317 ARG C NH2 1 +ATOM 4791 N N . ASP B 2 318 ? -45.393 16.946 -85.570 1.00 70.34 ? 318 ASP C N 1 +ATOM 4792 C CA . ASP B 2 318 ? -46.033 17.544 -86.737 1.00 68.18 ? 318 ASP C CA 1 +ATOM 4793 C C . ASP B 2 318 ? -45.351 17.175 -88.045 1.00 66.24 ? 318 ASP C C 1 +ATOM 4794 O O . ASP B 2 318 ? -45.742 17.696 -89.094 1.00 70.85 ? 318 ASP C O 1 +ATOM 4795 C CB . ASP B 2 318 ? -46.066 19.071 -86.600 1.00 73.49 ? 318 ASP C CB 1 +ATOM 4796 C CG . ASP B 2 318 ? -46.811 19.538 -85.357 1.00 75.22 ? 318 ASP C CG 1 +ATOM 4797 O OD1 . ASP B 2 318 ? -47.305 18.679 -84.594 1.00 81.71 ? 318 ASP C OD1 1 +ATOM 4798 O OD2 . ASP B 2 318 ? -46.872 20.767 -85.125 1.00 70.25 ? 318 ASP C OD2 1 +ATOM 4799 N N . VAL B 2 319 ? -44.362 16.285 -88.015 1.00 60.91 ? 319 VAL C N 1 +ATOM 4800 C CA . VAL B 2 319 ? -43.648 15.902 -89.227 1.00 60.06 ? 319 VAL C CA 1 +ATOM 4801 C C . VAL B 2 319 ? -43.529 14.385 -89.292 1.00 60.72 ? 319 VAL C C 1 +ATOM 4802 O O . VAL B 2 319 ? -42.497 13.847 -89.708 1.00 60.64 ? 319 VAL C O 1 +ATOM 4803 C CB . VAL B 2 319 ? -42.263 16.573 -89.303 1.00 53.24 ? 319 VAL C CB 1 +ATOM 4804 C CG1 . VAL B 2 319 ? -42.407 18.059 -89.576 1.00 57.41 ? 319 VAL C CG1 1 +ATOM 4805 C CG2 . VAL B 2 319 ? -41.494 16.353 -88.022 1.00 56.64 ? 319 VAL C CG2 1 +ATOM 4806 N N . THR B 2 320 ? -44.581 13.682 -88.879 1.00 57.44 ? 320 THR C N 1 +ATOM 4807 C CA . THR B 2 320 ? -44.611 12.231 -88.996 1.00 55.85 ? 320 THR C CA 1 +ATOM 4808 C C . THR B 2 320 ? -45.993 11.793 -89.447 1.00 54.67 ? 320 THR C C 1 +ATOM 4809 O O . THR B 2 320 ? -47.003 12.248 -88.903 1.00 49.73 ? 320 THR C O 1 +ATOM 4810 C CB . THR B 2 320 ? -44.239 11.536 -87.682 1.00 50.83 ? 320 THR C CB 1 +ATOM 4811 O OG1 . THR B 2 320 ? -44.464 10.128 -87.817 1.00 54.91 ? 320 THR C OG1 1 +ATOM 4812 C CG2 . THR B 2 320 ? -45.075 12.063 -86.538 1.00 50.24 ? 320 THR C CG2 1 +ATOM 4813 N N . ARG B 2 321 ? -46.028 10.948 -90.476 1.00 61.79 ? 321 ARG C N 1 +ATOM 4814 C CA . ARG B 2 321 ? -47.245 10.285 -90.923 1.00 69.21 ? 321 ARG C CA 1 +ATOM 4815 C C . ARG B 2 321 ? -47.381 8.879 -90.343 1.00 70.12 ? 321 ARG C C 1 +ATOM 4816 O O . ARG B 2 321 ? -48.141 8.060 -90.876 1.00 59.02 ? 321 ARG C O 1 +ATOM 4817 C CB . ARG B 2 321 ? -47.289 10.252 -92.452 1.00 73.83 ? 321 ARG C CB 1 +ATOM 4818 C CG . ARG B 2 321 ? -45.955 9.912 -93.113 1.00 77.33 ? 321 ARG C CG 1 +ATOM 4819 C CD . ARG B 2 321 ? -46.100 9.696 -94.616 1.00 82.22 ? 321 ARG C CD 1 +ATOM 4820 N NE . ARG B 2 321 ? -46.472 10.936 -95.293 1.00 90.85 ? 321 ARG C NE 1 +ATOM 4821 C CZ . ARG B 2 321 ? -45.602 11.792 -95.817 1.00 86.57 ? 321 ARG C CZ 1 +ATOM 4822 N NH1 . ARG B 2 321 ? -44.301 11.550 -95.736 1.00 84.22 ? 321 ARG C NH1 1 +ATOM 4823 N NH2 . ARG B 2 321 ? -46.033 12.896 -96.412 1.00 68.96 ? 321 ARG C NH2 1 +ATOM 4824 N N . ASP B 2 322 ? -46.675 8.596 -89.248 1.00 70.25 ? 322 ASP C N 1 +ATOM 4825 C CA . ASP B 2 322 ? -46.711 7.297 -88.583 1.00 69.92 ? 322 ASP C CA 1 +ATOM 4826 C C . ASP B 2 322 ? -47.896 7.274 -87.620 1.00 70.70 ? 322 ASP C C 1 +ATOM 4827 O O . ASP B 2 322 ? -47.902 7.992 -86.614 1.00 65.12 ? 322 ASP C O 1 +ATOM 4828 C CB . ASP B 2 322 ? -45.390 7.051 -87.855 1.00 60.73 ? 322 ASP C CB 1 +ATOM 4829 C CG . ASP B 2 322 ? -45.276 5.646 -87.292 1.00 69.94 ? 322 ASP C CG 1 +ATOM 4830 O OD1 . ASP B 2 322 ? -46.065 5.298 -86.391 1.00 76.42 ? 322 ASP C OD1 1 +ATOM 4831 O OD2 . ASP B 2 322 ? -44.377 4.897 -87.732 1.00 70.76 ? 322 ASP C OD2 1 +ATOM 4832 N N . LYS B 2 323 ? -48.898 6.440 -87.925 1.00 69.19 ? 323 LYS C N 1 +ATOM 4833 C CA . LYS B 2 323 ? -50.107 6.389 -87.106 1.00 66.51 ? 323 LYS C CA 1 +ATOM 4834 C C . LYS B 2 323 ? -49.817 5.880 -85.698 1.00 69.96 ? 323 LYS C C 1 +ATOM 4835 O O . LYS B 2 323 ? -50.466 6.311 -84.738 1.00 67.36 ? 323 LYS C O 1 +ATOM 4836 C CB . LYS B 2 323 ? -51.153 5.491 -87.775 1.00 68.88 ? 323 LYS C CB 1 +ATOM 4837 C CG . LYS B 2 323 ? -51.505 5.882 -89.207 1.00 92.27 ? 323 LYS C CG 1 +ATOM 4838 C CD . LYS B 2 323 ? -52.510 4.913 -89.841 1.00 80.55 ? 323 LYS C CD 1 +ATOM 4839 C CE . LYS B 2 323 ? -53.839 4.904 -89.105 1.00 75.63 ? 323 LYS C CE 1 +ATOM 4840 N NZ . LYS B 2 323 ? -54.797 3.947 -89.728 1.00 60.64 ? 323 LYS C NZ 1 +ATOM 4841 N N . LYS B 2 324 ? -48.842 4.977 -85.557 1.00 72.92 ? 324 LYS C N 1 +ATOM 4842 C CA . LYS B 2 324 ? -48.511 4.416 -84.251 1.00 62.82 ? 324 LYS C CA 1 +ATOM 4843 C C . LYS B 2 324 ? -47.844 5.457 -83.363 1.00 58.14 ? 324 LYS C C 1 +ATOM 4844 O O . LYS B 2 324 ? -48.235 5.647 -82.206 1.00 58.23 ? 324 LYS C O 1 +ATOM 4845 C CB . LYS B 2 324 ? -47.591 3.204 -84.422 1.00 71.50 ? 324 LYS C CB 1 +ATOM 4846 C CG . LYS B 2 324 ? -47.809 2.424 -85.715 1.00 79.16 ? 324 LYS C CG 1 +ATOM 4847 C CD . LYS B 2 324 ? -46.666 1.445 -85.983 1.00 79.23 ? 324 LYS C CD 1 +ATOM 4848 C CE . LYS B 2 324 ? -46.501 0.452 -84.838 1.00 82.01 ? 324 LYS C CE 1 +ATOM 4849 N NZ . LYS B 2 324 ? -47.779 -0.257 -84.531 1.00 76.22 ? 324 LYS C NZ 1 +ATOM 4850 N N . LEU B 2 325 ? -46.818 6.128 -83.890 1.00 61.23 ? 325 LEU C N 1 +ATOM 4851 C CA . LEU B 2 325 ? -46.055 7.087 -83.102 1.00 53.86 ? 325 LEU C CA 1 +ATOM 4852 C C . LEU B 2 325 ? -46.900 8.297 -82.743 1.00 51.32 ? 325 LEU C C 1 +ATOM 4853 O O . LEU B 2 325 ? -46.794 8.829 -81.632 1.00 46.53 ? 325 LEU C O 1 +ATOM 4854 C CB . LEU B 2 325 ? -44.805 7.512 -83.877 1.00 52.64 ? 325 LEU C CB 1 +ATOM 4855 C CG . LEU B 2 325 ? -43.735 8.412 -83.254 1.00 41.42 ? 325 LEU C CG 1 +ATOM 4856 C CD1 . LEU B 2 325 ? -44.035 9.863 -83.524 1.00 46.68 ? 325 LEU C CD1 1 +ATOM 4857 C CD2 . LEU B 2 325 ? -43.592 8.175 -81.767 1.00 44.94 ? 325 LEU C CD2 1 +ATOM 4858 N N . TRP B 2 326 ? -47.733 8.758 -83.672 1.00 54.43 ? 326 TRP C N 1 +ATOM 4859 C CA . TRP B 2 326 ? -48.454 9.995 -83.417 1.00 61.34 ? 326 TRP C CA 1 +ATOM 4860 C C . TRP B 2 326 ? -49.568 9.802 -82.395 1.00 65.77 ? 326 TRP C C 1 +ATOM 4861 O O . TRP B 2 326 ? -49.800 10.692 -81.567 1.00 67.17 ? 326 TRP C O 1 +ATOM 4862 C CB . TRP B 2 326 ? -48.993 10.569 -84.728 1.00 64.21 ? 326 TRP C CB 1 +ATOM 4863 C CG . TRP B 2 326 ? -49.642 11.902 -84.543 1.00 64.21 ? 326 TRP C CG 1 +ATOM 4864 C CD1 . TRP B 2 326 ? -49.030 13.124 -84.560 1.00 60.10 ? 326 TRP C CD1 1 +ATOM 4865 C CD2 . TRP B 2 326 ? -51.037 12.153 -84.340 1.00 62.01 ? 326 TRP C CD2 1 +ATOM 4866 N NE1 . TRP B 2 326 ? -49.957 14.118 -84.357 1.00 67.08 ? 326 TRP C NE1 1 +ATOM 4867 C CE2 . TRP B 2 326 ? -51.197 13.547 -84.223 1.00 70.85 ? 326 TRP C CE2 1 +ATOM 4868 C CE3 . TRP B 2 326 ? -52.165 11.332 -84.238 1.00 54.10 ? 326 TRP C CE3 1 +ATOM 4869 C CZ2 . TRP B 2 326 ? -52.441 14.138 -84.011 1.00 66.96 ? 326 TRP C CZ2 1 +ATOM 4870 C CZ3 . TRP B 2 326 ? -53.396 11.920 -84.028 1.00 52.48 ? 326 TRP C CZ3 1 +ATOM 4871 C CH2 . TRP B 2 326 ? -53.525 13.309 -83.916 1.00 54.42 ? 326 TRP C CH2 1 +ATOM 4872 N N . ARG B 2 327 ? -50.229 8.639 -82.392 1.00 62.71 ? 327 ARG C N 1 +ATOM 4873 C CA . ARG B 2 327 ? -51.367 8.437 -81.498 1.00 61.35 ? 327 ARG C CA 1 +ATOM 4874 C C . ARG B 2 327 ? -50.976 8.357 -80.027 1.00 59.18 ? 327 ARG C C 1 +ATOM 4875 O O . ARG B 2 327 ? -51.861 8.199 -79.179 1.00 61.53 ? 327 ARG C O 1 +ATOM 4876 C CB . ARG B 2 327 ? -52.130 7.169 -81.889 1.00 56.43 ? 327 ARG C CB 1 +ATOM 4877 C CG . ARG B 2 327 ? -52.970 7.323 -83.130 1.00 57.51 ? 327 ARG C CG 1 +ATOM 4878 C CD . ARG B 2 327 ? -54.359 6.756 -82.915 1.00 74.63 ? 327 ARG C CD 1 +ATOM 4879 N NE . ARG B 2 327 ? -54.933 6.229 -84.149 1.00 92.00 ? 327 ARG C NE 1 +ATOM 4880 C CZ . ARG B 2 327 ? -54.810 4.967 -84.545 1.00 94.12 ? 327 ARG C CZ 1 +ATOM 4881 N NH1 . ARG B 2 327 ? -54.132 4.102 -83.798 1.00 95.92 ? 327 ARG C NH1 1 +ATOM 4882 N NH2 . ARG B 2 327 ? -55.365 4.569 -85.684 1.00 84.51 ? 327 ARG C NH2 1 +ATOM 4883 N N . THR B 2 328 ? -49.697 8.494 -79.690 1.00 54.79 ? 328 THR C N 1 +ATOM 4884 C CA . THR B 2 328 ? -49.258 8.460 -78.304 1.00 54.42 ? 328 THR C CA 1 +ATOM 4885 C C . THR B 2 328 ? -48.834 9.835 -77.815 1.00 57.25 ? 328 THR C C 1 +ATOM 4886 O O . THR B 2 328 ? -48.228 9.944 -76.745 1.00 58.03 ? 328 THR C O 1 +ATOM 4887 C CB . THR B 2 328 ? -48.111 7.465 -78.114 1.00 54.50 ? 328 THR C CB 1 +ATOM 4888 O OG1 . THR B 2 328 ? -46.918 7.987 -78.709 1.00 51.96 ? 328 THR C OG1 1 +ATOM 4889 C CG2 . THR B 2 328 ? -48.452 6.128 -78.762 1.00 53.08 ? 328 THR C CG2 1 +ATOM 4890 N N . PHE B 2 329 ? -49.110 10.883 -78.585 1.00 56.85 ? 329 PHE C N 1 +ATOM 4891 C CA . PHE B 2 329 ? -48.751 12.241 -78.188 1.00 56.80 ? 329 PHE C CA 1 +ATOM 4892 C C . PHE B 2 329 ? -49.891 12.807 -77.353 1.00 54.09 ? 329 PHE C C 1 +ATOM 4893 O O . PHE B 2 329 ? -50.917 13.233 -77.888 1.00 56.42 ? 329 PHE C O 1 +ATOM 4894 C CB . PHE B 2 329 ? -48.452 13.107 -79.405 1.00 54.97 ? 329 PHE C CB 1 +ATOM 4895 C CG . PHE B 2 329 ? -46.986 13.292 -79.667 1.00 50.06 ? 329 PHE C CG 1 +ATOM 4896 C CD1 . PHE B 2 329 ? -46.292 12.397 -80.461 1.00 51.01 ? 329 PHE C CD1 1 +ATOM 4897 C CD2 . PHE B 2 329 ? -46.298 14.355 -79.104 1.00 48.91 ? 329 PHE C CD2 1 +ATOM 4898 C CE1 . PHE B 2 329 ? -44.941 12.568 -80.698 1.00 52.57 ? 329 PHE C CE1 1 +ATOM 4899 C CE2 . PHE B 2 329 ? -44.949 14.530 -79.336 1.00 46.40 ? 329 PHE C CE2 1 +ATOM 4900 C CZ . PHE B 2 329 ? -44.269 13.636 -80.134 1.00 49.24 ? 329 PHE C CZ 1 +ATOM 4901 N N . PHE B 2 330 ? -49.729 12.764 -76.035 1.00 53.59 ? 330 PHE C N 1 +ATOM 4902 C CA . PHE B 2 330 ? -50.691 13.305 -75.088 1.00 58.50 ? 330 PHE C CA 1 +ATOM 4903 C C . PHE B 2 330 ? -50.077 14.459 -74.299 1.00 68.66 ? 330 PHE C C 1 +ATOM 4904 O O . PHE B 2 330 ? -48.854 14.629 -74.248 1.00 62.30 ? 330 PHE C O 1 +ATOM 4905 C CB . PHE B 2 330 ? -51.177 12.211 -74.132 1.00 56.84 ? 330 PHE C CB 1 +ATOM 4906 C CG . PHE B 2 330 ? -50.105 11.694 -73.218 1.00 58.33 ? 330 PHE C CG 1 +ATOM 4907 C CD1 . PHE B 2 330 ? -49.244 10.696 -73.632 1.00 57.51 ? 330 PHE C CD1 1 +ATOM 4908 C CD2 . PHE B 2 330 ? -49.950 12.220 -71.949 1.00 64.94 ? 330 PHE C CD2 1 +ATOM 4909 C CE1 . PHE B 2 330 ? -48.255 10.228 -72.793 1.00 55.28 ? 330 PHE C CE1 1 +ATOM 4910 C CE2 . PHE B 2 330 ? -48.962 11.759 -71.108 1.00 61.05 ? 330 PHE C CE2 1 +ATOM 4911 C CZ . PHE B 2 330 ? -48.117 10.758 -71.528 1.00 55.53 ? 330 PHE C CZ 1 +ATOM 4912 N N . VAL B 2 331 ? -50.947 15.251 -73.669 1.00 74.98 ? 331 VAL C N 1 +ATOM 4913 C CA . VAL B 2 331 ? -50.540 16.358 -72.808 1.00 66.42 ? 331 VAL C CA 1 +ATOM 4914 C C . VAL B 2 331 ? -50.792 15.961 -71.361 1.00 63.54 ? 331 VAL C C 1 +ATOM 4915 O O . VAL B 2 331 ? -51.904 15.544 -71.008 1.00 50.29 ? 331 VAL C O 1 +ATOM 4916 C CB . VAL B 2 331 ? -51.293 17.653 -73.153 1.00 68.42 ? 331 VAL C CB 1 +ATOM 4917 C CG1 . VAL B 2 331 ? -50.683 18.836 -72.394 1.00 67.67 ? 331 VAL C CG1 1 +ATOM 4918 C CG2 . VAL B 2 331 ? -51.297 17.882 -74.659 1.00 74.56 ? 331 VAL C CG2 1 +ATOM 4919 N N . SER B 2 332 ? -49.783 16.144 -70.521 1.00 63.72 ? 332 SER C N 1 +ATOM 4920 C CA . SER B 2 332 ? -49.805 15.649 -69.152 1.00 61.72 ? 332 SER C CA 1 +ATOM 4921 C C . SER B 2 332 ? -50.510 16.645 -68.244 1.00 67.00 ? 332 SER C C 1 +ATOM 4922 O O . SER B 2 332 ? -50.775 17.787 -68.628 1.00 69.94 ? 332 SER C O 1 +ATOM 4923 C CB . SER B 2 332 ? -48.375 15.391 -68.683 1.00 52.84 ? 332 SER C CB 1 +ATOM 4924 O OG . SER B 2 332 ? -47.676 16.601 -68.449 1.00 53.79 ? 332 SER C OG 1 +ATOM 4925 N N . PRO B 2 333 ? -50.869 16.235 -67.023 1.00 64.17 ? 333 PRO C N 1 +ATOM 4926 C CA . PRO B 2 333 ? -51.448 17.204 -66.081 1.00 59.00 ? 333 PRO C CA 1 +ATOM 4927 C C . PRO B 2 333 ? -50.522 18.369 -65.767 1.00 63.46 ? 333 PRO C C 1 +ATOM 4928 O O . PRO B 2 333 ? -51.014 19.445 -65.408 1.00 68.40 ? 333 PRO C O 1 +ATOM 4929 C CB . PRO B 2 333 ? -51.741 16.353 -64.839 1.00 56.80 ? 333 PRO C CB 1 +ATOM 4930 C CG . PRO B 2 333 ? -51.970 14.987 -65.379 1.00 48.09 ? 333 PRO C CG 1 +ATOM 4931 C CD . PRO B 2 333 ? -51.011 14.851 -66.533 1.00 60.40 ? 333 PRO C CD 1 +ATOM 4932 N N . ALA B 2 334 ? -49.207 18.208 -65.921 1.00 55.22 ? 334 ALA C N 1 +ATOM 4933 C CA . ALA B 2 334 ? -48.283 19.325 -65.770 1.00 58.32 ? 334 ALA C CA 1 +ATOM 4934 C C . ALA B 2 334 ? -48.206 20.194 -67.020 1.00 64.76 ? 334 ALA C C 1 +ATOM 4935 O O . ALA B 2 334 ? -47.265 20.984 -67.149 1.00 63.14 ? 334 ALA C O 1 +ATOM 4936 C CB . ALA B 2 334 ? -46.887 18.814 -65.407 1.00 58.18 ? 334 ALA C CB 1 +ATOM 4937 N N . ASN B 2 335 ? -49.168 20.042 -67.935 1.00 71.73 ? 335 ASN C N 1 +ATOM 4938 C CA . ASN B 2 335 ? -49.256 20.803 -69.186 1.00 73.10 ? 335 ASN C CA 1 +ATOM 4939 C C . ASN B 2 335 ? -48.012 20.635 -70.054 1.00 73.80 ? 335 ASN C C 1 +ATOM 4940 O O . ASN B 2 335 ? -47.684 21.503 -70.866 1.00 82.20 ? 335 ASN C O 1 +ATOM 4941 C CB . ASN B 2 335 ? -49.537 22.286 -68.932 1.00 71.34 ? 335 ASN C CB 1 +ATOM 4942 C CG . ASN B 2 335 ? -50.310 22.927 -70.069 1.00 80.22 ? 335 ASN C CG 1 +ATOM 4943 O OD1 . ASN B 2 335 ? -51.539 22.863 -70.104 1.00 82.28 ? 335 ASN C OD1 1 +ATOM 4944 N ND2 . ASN B 2 335 ? -49.595 23.552 -71.004 1.00 85.79 ? 335 ASN C ND2 1 +ATOM 4945 N N . ASN B 2 336 ? -47.317 19.517 -69.899 1.00 66.80 ? 336 ASN C N 1 +ATOM 4946 C CA . ASN B 2 336 ? -46.193 19.178 -70.753 1.00 63.41 ? 336 ASN C CA 1 +ATOM 4947 C C . ASN B 2 336 ? -46.635 18.168 -71.802 1.00 71.74 ? 336 ASN C C 1 +ATOM 4948 O O . ASN B 2 336 ? -47.611 17.434 -71.615 1.00 62.81 ? 336 ASN C O 1 +ATOM 4949 C CB . ASN B 2 336 ? -45.030 18.622 -69.937 1.00 55.70 ? 336 ASN C CB 1 +ATOM 4950 C CG . ASN B 2 336 ? -44.562 19.589 -68.886 1.00 61.68 ? 336 ASN C CG 1 +ATOM 4951 O OD1 . ASN B 2 336 ? -44.767 20.793 -69.011 1.00 67.11 ? 336 ASN C OD1 1 +ATOM 4952 N ND2 . ASN B 2 336 ? -43.935 19.073 -67.838 1.00 65.70 ? 336 ASN C ND2 1 +ATOM 4953 N N . ILE B 2 337 ? -45.947 18.186 -72.937 1.00 78.68 ? 337 ILE C N 1 +ATOM 4954 C CA . ILE B 2 337 ? -46.224 17.255 -74.023 1.00 75.59 ? 337 ILE C CA 1 +ATOM 4955 C C . ILE B 2 337 ? -45.364 16.013 -73.830 1.00 68.18 ? 337 ILE C C 1 +ATOM 4956 O O . ILE B 2 337 ? -44.175 16.102 -73.488 1.00 52.65 ? 337 ILE C O 1 +ATOM 4957 C CB . ILE B 2 337 ? -45.974 17.908 -75.396 1.00 70.92 ? 337 ILE C CB 1 +ATOM 4958 C CG1 . ILE B 2 337 ? -46.644 19.281 -75.467 1.00 76.41 ? 337 ILE C CG1 1 +ATOM 4959 C CG2 . ILE B 2 337 ? -46.550 17.038 -76.500 1.00 58.79 ? 337 ILE C CG2 1 +ATOM 4960 C CD1 . ILE B 2 337 ? -46.469 19.986 -76.803 1.00 79.25 ? 337 ILE C CD1 1 +ATOM 4961 N N . CYS B 2 338 ? -45.979 14.847 -74.022 1.00 72.62 ? 338 CYS C N 1 +ATOM 4962 C CA . CYS B 2 338 ? -45.310 13.569 -73.835 1.00 67.23 ? 338 CYS C CA 1 +ATOM 4963 C C . CYS B 2 338 ? -45.670 12.628 -74.975 1.00 58.86 ? 338 CYS C C 1 +ATOM 4964 O O . CYS B 2 338 ? -46.735 12.734 -75.590 1.00 54.92 ? 338 CYS C O 1 +ATOM 4965 C CB . CYS B 2 338 ? -45.700 12.900 -72.517 1.00 67.45 ? 338 CYS C CB 1 +ATOM 4966 S SG . CYS B 2 338 ? -45.497 13.891 -71.047 1.00 73.80 ? 338 CYS C SG 1 +ATOM 4967 N N . PHE B 2 339 ? -44.785 11.665 -75.206 1.00 54.55 ? 339 PHE C N 1 +ATOM 4968 C CA . PHE B 2 339 ? -45.037 10.586 -76.146 1.00 54.49 ? 339 PHE C CA 1 +ATOM 4969 C C . PHE B 2 339 ? -44.186 9.401 -75.726 1.00 61.41 ? 339 PHE C C 1 +ATOM 4970 O O . PHE B 2 339 ? -43.107 9.573 -75.150 1.00 58.98 ? 339 PHE C O 1 +ATOM 4971 C CB . PHE B 2 339 ? -44.705 11.002 -77.582 1.00 54.27 ? 339 PHE C CB 1 +ATOM 4972 C CG . PHE B 2 339 ? -43.234 10.966 -77.899 1.00 51.06 ? 339 PHE C CG 1 +ATOM 4973 C CD1 . PHE B 2 339 ? -42.388 11.968 -77.454 1.00 52.02 ? 339 PHE C CD1 1 +ATOM 4974 C CD2 . PHE B 2 339 ? -42.703 9.943 -78.665 1.00 51.24 ? 339 PHE C CD2 1 +ATOM 4975 C CE1 . PHE B 2 339 ? -41.038 11.935 -77.747 1.00 46.49 ? 339 PHE C CE1 1 +ATOM 4976 C CE2 . PHE B 2 339 ? -41.356 9.909 -78.964 1.00 48.71 ? 339 PHE C CE2 1 +ATOM 4977 C CZ . PHE B 2 339 ? -40.523 10.906 -78.503 1.00 44.12 ? 339 PHE C CZ 1 +ATOM 4978 N N . TYR B 2 340 ? -44.672 8.199 -76.031 1.00 58.58 ? 340 TYR C N 1 +ATOM 4979 C CA . TYR B 2 340 ? -43.950 6.995 -75.637 1.00 60.21 ? 340 TYR C CA 1 +ATOM 4980 C C . TYR B 2 340 ? -43.714 6.072 -76.828 1.00 59.99 ? 340 TYR C C 1 +ATOM 4981 O O . TYR B 2 340 ? -42.738 5.315 -76.843 1.00 63.64 ? 340 TYR C O 1 +ATOM 4982 C CB . TYR B 2 340 ? -44.685 6.262 -74.503 1.00 50.67 ? 340 TYR C CB 1 +ATOM 4983 C CG . TYR B 2 340 ? -46.172 6.063 -74.691 1.00 43.99 ? 340 TYR C CG 1 +ATOM 4984 C CD1 . TYR B 2 340 ? -47.070 7.078 -74.401 1.00 44.70 ? 340 TYR C CD1 1 +ATOM 4985 C CD2 . TYR B 2 340 ? -46.680 4.847 -75.116 1.00 48.77 ? 340 TYR C CD2 1 +ATOM 4986 C CE1 . TYR B 2 340 ? -48.434 6.895 -74.562 1.00 50.42 ? 340 TYR C CE1 1 +ATOM 4987 C CE2 . TYR B 2 340 ? -48.040 4.653 -75.277 1.00 50.88 ? 340 TYR C CE2 1 +ATOM 4988 C CZ . TYR B 2 340 ? -48.912 5.679 -74.998 1.00 48.62 ? 340 TYR C CZ 1 +ATOM 4989 O OH . TYR B 2 340 ? -50.267 5.486 -75.160 1.00 42.46 ? 340 TYR C OH 1 +ATOM 4990 N N . GLY B 2 341 ? -44.569 6.135 -77.837 1.00 49.93 ? 341 GLY C N 1 +ATOM 4991 C CA . GLY B 2 341 ? -44.384 5.279 -78.987 1.00 50.84 ? 341 GLY C CA 1 +ATOM 4992 C C . GLY B 2 341 ? -45.005 3.911 -78.778 1.00 62.28 ? 341 GLY C C 1 +ATOM 4993 O O . GLY B 2 341 ? -45.948 3.730 -78.003 1.00 64.20 ? 341 GLY C O 1 +ATOM 4994 N N . GLU B 2 342 ? -44.480 2.937 -79.512 1.00 65.83 ? 342 GLU C N 1 +ATOM 4995 C CA . GLU B 2 342 ? -45.004 1.578 -79.452 1.00 75.00 ? 342 GLU C CA 1 +ATOM 4996 C C . GLU B 2 342 ? -43.880 0.582 -79.729 1.00 64.90 ? 342 GLU C C 1 +ATOM 4997 O O . GLU B 2 342 ? -43.913 -0.179 -80.692 1.00 63.77 ? 342 GLU C O 1 +ATOM 4998 C CB . GLU B 2 342 ? -46.162 1.412 -80.437 1.00 85.61 ? 342 GLU C CB 1 +ATOM 4999 C CG . GLU B 2 342 ? -47.406 0.730 -79.866 1.00 86.07 ? 342 GLU C CG 1 +ATOM 5000 C CD . GLU B 2 342 ? -48.621 0.851 -80.782 1.00 96.46 ? 342 GLU C CD 1 +ATOM 5001 O OE1 . GLU B 2 342 ? -48.444 0.957 -82.015 1.00 97.52 ? 342 GLU C OE1 1 +ATOM 5002 O OE2 . GLU B 2 342 ? -49.760 0.837 -80.268 1.00 111.18 ? 342 GLU C OE2 1 +ATOM 5003 N N . CYS B 2 343 ? -42.841 0.585 -78.893 1.00 57.26 ? 343 CYS C N 1 +ATOM 5004 C CA . CYS B 2 343 ? -41.822 -0.454 -78.999 1.00 64.53 ? 343 CYS C CA 1 +ATOM 5005 C C . CYS B 2 343 ? -42.145 -1.609 -78.054 1.00 63.63 ? 343 CYS C C 1 +ATOM 5006 O O . CYS B 2 343 ? -43.275 -2.102 -78.042 1.00 71.44 ? 343 CYS C O 1 +ATOM 5007 C CB . CYS B 2 343 ? -40.430 0.119 -78.722 1.00 64.92 ? 343 CYS C CB 1 +ATOM 5008 S SG . CYS B 2 343 ? -40.132 0.533 -77.000 1.00 61.49 ? 343 CYS C SG 1 +ATOM 5009 N N . SER B 2 344 ? -41.183 -2.029 -77.230 1.00 63.48 ? 344 SER C N 1 +ATOM 5010 C CA . SER B 2 344 ? -41.378 -3.190 -76.363 1.00 64.87 ? 344 SER C CA 1 +ATOM 5011 C C . SER B 2 344 ? -40.837 -2.959 -74.956 1.00 57.53 ? 344 SER C C 1 +ATOM 5012 O O . SER B 2 344 ? -41.389 -3.484 -73.989 1.00 52.01 ? 344 SER C O 1 +ATOM 5013 C CB . SER B 2 344 ? -40.729 -4.436 -76.991 1.00 58.93 ? 344 SER C CB 1 +ATOM 5014 O OG . SER B 2 344 ? -39.312 -4.341 -76.987 1.00 57.33 ? 344 SER C OG 1 +ATOM 5015 N N . TYR B 2 345 ? -39.748 -2.212 -74.833 1.00 61.29 ? 345 TYR C N 1 +ATOM 5016 C CA . TYR B 2 345 ? -39.143 -1.867 -73.555 1.00 57.99 ? 345 TYR C CA 1 +ATOM 5017 C C . TYR B 2 345 ? -39.424 -0.406 -73.216 1.00 59.20 ? 345 TYR C C 1 +ATOM 5018 O O . TYR B 2 345 ? -38.942 0.496 -73.912 1.00 62.54 ? 345 TYR C O 1 +ATOM 5019 C CB . TYR B 2 345 ? -37.635 -2.111 -73.582 1.00 61.45 ? 345 TYR C CB 1 +ATOM 5020 C CG . TYR B 2 345 ? -37.221 -3.371 -72.873 1.00 60.16 ? 345 TYR C CG 1 +ATOM 5021 C CD1 . TYR B 2 345 ? -38.136 -4.376 -72.616 1.00 54.40 ? 345 TYR C CD1 1 +ATOM 5022 C CD2 . TYR B 2 345 ? -35.903 -3.560 -72.475 1.00 58.47 ? 345 TYR C CD2 1 +ATOM 5023 C CE1 . TYR B 2 345 ? -37.756 -5.532 -71.975 1.00 55.80 ? 345 TYR C CE1 1 +ATOM 5024 C CE2 . TYR B 2 345 ? -35.516 -4.708 -71.836 1.00 58.38 ? 345 TYR C CE2 1 +ATOM 5025 C CZ . TYR B 2 345 ? -36.444 -5.694 -71.582 1.00 58.64 ? 345 TYR C CZ 1 +ATOM 5026 O OH . TYR B 2 345 ? -36.050 -6.848 -70.944 1.00 59.75 ? 345 TYR C OH 1 +ATOM 5027 N N . TYR B 2 346 ? -40.157 -0.183 -72.121 1.00 60.97 ? 346 TYR C N 1 +ATOM 5028 C CA . TYR B 2 346 ? -40.430 1.153 -71.590 1.00 55.56 ? 346 TYR C CA 1 +ATOM 5029 C C . TYR B 2 346 ? -41.150 2.019 -72.623 1.00 61.83 ? 346 TYR C C 1 +ATOM 5030 O O . TYR B 2 346 ? -40.895 3.218 -72.740 1.00 63.76 ? 346 TYR C O 1 +ATOM 5031 C CB . TYR B 2 346 ? -39.140 1.826 -71.098 1.00 51.92 ? 346 TYR C CB 1 +ATOM 5032 C CG . TYR B 2 346 ? -38.247 0.923 -70.267 1.00 53.71 ? 346 TYR C CG 1 +ATOM 5033 C CD1 . TYR B 2 346 ? -38.765 0.159 -69.225 1.00 59.23 ? 346 TYR C CD1 1 +ATOM 5034 C CD2 . TYR B 2 346 ? -36.885 0.830 -70.528 1.00 54.36 ? 346 TYR C CD2 1 +ATOM 5035 C CE1 . TYR B 2 346 ? -37.943 -0.671 -68.464 1.00 62.11 ? 346 TYR C CE1 1 +ATOM 5036 C CE2 . TYR B 2 346 ? -36.058 0.005 -69.773 1.00 56.38 ? 346 TYR C CE2 1 +ATOM 5037 C CZ . TYR B 2 346 ? -36.590 -0.742 -68.744 1.00 61.50 ? 346 TYR C CZ 1 +ATOM 5038 O OH . TYR B 2 346 ? -35.763 -1.559 -68.001 1.00 57.82 ? 346 TYR C OH 1 +ATOM 5039 N N . CYS B 2 347 ? -42.074 1.409 -73.364 1.00 62.18 ? 347 CYS C N 1 +ATOM 5040 C CA . CYS B 2 347 ? -42.919 2.117 -74.322 1.00 61.15 ? 347 CYS C CA 1 +ATOM 5041 C C . CYS B 2 347 ? -44.367 2.047 -73.850 1.00 56.64 ? 347 CYS C C 1 +ATOM 5042 O O . CYS B 2 347 ? -45.223 1.382 -74.434 1.00 53.90 ? 347 CYS C O 1 +ATOM 5043 C CB . CYS B 2 347 ? -42.761 1.532 -75.747 1.00 67.45 ? 347 CYS C CB 1 +ATOM 5044 S SG . CYS B 2 347 ? -41.324 2.148 -76.678 1.00 85.37 ? 347 CYS C SG 1 +ATOM 5045 N N . SER B 2 348 ? -44.630 2.764 -72.762 1.00 56.65 ? 348 SER C N 1 +ATOM 5046 C CA . SER B 2 348 ? -45.967 2.854 -72.209 1.00 56.36 ? 348 SER C CA 1 +ATOM 5047 C C . SER B 2 348 ? -46.109 4.220 -71.563 1.00 51.66 ? 348 SER C C 1 +ATOM 5048 O O . SER B 2 348 ? -45.142 4.977 -71.448 1.00 50.77 ? 348 SER C O 1 +ATOM 5049 C CB . SER B 2 348 ? -46.231 1.713 -71.219 1.00 59.86 ? 348 SER C CB 1 +ATOM 5050 O OG . SER B 2 348 ? -45.142 1.581 -70.321 1.00 61.91 ? 348 SER C OG 1 +ATOM 5051 N N . THR B 2 349 ? -47.328 4.516 -71.112 1.00 43.96 ? 349 THR C N 1 +ATOM 5052 C CA . THR B 2 349 ? -47.607 5.832 -70.554 1.00 44.39 ? 349 THR C CA 1 +ATOM 5053 C C . THR B 2 349 ? -46.674 6.144 -69.394 1.00 43.98 ? 349 THR C C 1 +ATOM 5054 O O . THR B 2 349 ? -46.148 7.258 -69.286 1.00 38.00 ? 349 THR C O 1 +ATOM 5055 C CB . THR B 2 349 ? -49.060 5.881 -70.095 1.00 43.37 ? 349 THR C CB 1 +ATOM 5056 O OG1 . THR B 2 349 ? -49.910 5.424 -71.154 1.00 40.31 ? 349 THR C OG1 1 +ATOM 5057 C CG2 . THR B 2 349 ? -49.450 7.294 -69.696 1.00 45.52 ? 349 THR C CG2 1 +ATOM 5058 N N . GLU B 2 350 ? -46.399 5.146 -68.562 1.00 48.31 ? 350 GLU C N 1 +ATOM 5059 C CA . GLU B 2 350 ? -45.626 5.319 -67.344 1.00 46.84 ? 350 GLU C CA 1 +ATOM 5060 C C . GLU B 2 350 ? -44.133 5.452 -67.600 1.00 48.88 ? 350 GLU C C 1 +ATOM 5061 O O . GLU B 2 350 ? -43.362 5.542 -66.638 1.00 47.06 ? 350 GLU C O 1 +ATOM 5062 C CB . GLU B 2 350 ? -45.904 4.157 -66.385 1.00 48.43 ? 350 GLU C CB 1 +ATOM 5063 C CG . GLU B 2 350 ? -46.300 2.838 -67.056 1.00 53.13 ? 350 GLU C CG 1 +ATOM 5064 C CD . GLU B 2 350 ? -47.803 2.699 -67.325 1.00 51.30 ? 350 GLU C CD 1 +ATOM 5065 O OE1 . GLU B 2 350 ? -48.307 3.338 -68.272 1.00 56.47 ? 350 GLU C OE1 1 +ATOM 5066 O OE2 . GLU B 2 350 ? -48.481 1.941 -66.597 1.00 45.12 ? 350 GLU C OE2 1 +ATOM 5067 N N . HIS B 2 351 ? -43.702 5.444 -68.861 1.00 49.52 ? 351 HIS C N 1 +ATOM 5068 C CA . HIS B 2 351 ? -42.331 5.809 -69.196 1.00 61.57 ? 351 HIS C CA 1 +ATOM 5069 C C . HIS B 2 351 ? -42.285 6.893 -70.263 1.00 56.81 ? 351 HIS C C 1 +ATOM 5070 O O . HIS B 2 351 ? -41.266 7.039 -70.948 1.00 53.64 ? 351 HIS C O 1 +ATOM 5071 C CB . HIS B 2 351 ? -41.525 4.591 -69.637 1.00 60.66 ? 351 HIS C CB 1 +ATOM 5072 C CG . HIS B 2 351 ? -41.047 3.757 -68.495 1.00 53.71 ? 351 HIS C CG 1 +ATOM 5073 N ND1 . HIS B 2 351 ? -41.694 2.611 -68.086 1.00 53.92 ? 351 HIS C ND1 1 +ATOM 5074 C CD2 . HIS B 2 351 ? -40.004 3.924 -67.649 1.00 47.94 ? 351 HIS C CD2 1 +ATOM 5075 C CE1 . HIS B 2 351 ? -41.058 2.096 -67.050 1.00 55.89 ? 351 HIS C CE1 1 +ATOM 5076 N NE2 . HIS B 2 351 ? -40.029 2.875 -66.764 1.00 59.31 ? 351 HIS C NE2 1 +ATOM 5077 N N . ALA B 2 352 ? -43.358 7.672 -70.386 1.00 52.91 ? 352 ALA C N 1 +ATOM 5078 C CA . ALA B 2 352 ? -43.456 8.658 -71.449 1.00 52.51 ? 352 ALA C CA 1 +ATOM 5079 C C . ALA B 2 352 ? -42.315 9.659 -71.370 1.00 51.34 ? 352 ALA C C 1 +ATOM 5080 O O . ALA B 2 352 ? -41.871 10.042 -70.285 1.00 53.01 ? 352 ALA C O 1 +ATOM 5081 C CB . ALA B 2 352 ? -44.797 9.387 -71.376 1.00 49.25 ? 352 ALA C CB 1 +ATOM 5082 N N . LEU B 2 353 ? -41.808 10.039 -72.533 1.00 51.09 ? 353 LEU C N 1 +ATOM 5083 C CA . LEU B 2 353 ? -40.773 11.054 -72.633 1.00 60.26 ? 353 LEU C CA 1 +ATOM 5084 C C . LEU B 2 353 ? -41.440 12.415 -72.763 1.00 64.98 ? 353 LEU C C 1 +ATOM 5085 O O . LEU B 2 353 ? -42.268 12.624 -73.656 1.00 63.09 ? 353 LEU C O 1 +ATOM 5086 C CB . LEU B 2 353 ? -39.852 10.778 -73.816 1.00 56.10 ? 353 LEU C CB 1 +ATOM 5087 C CG . LEU B 2 353 ? -39.190 9.407 -73.764 1.00 57.86 ? 353 LEU C CG 1 +ATOM 5088 C CD1 . LEU B 2 353 ? -38.419 9.176 -75.035 1.00 59.34 ? 353 LEU C CD1 1 +ATOM 5089 C CD2 . LEU B 2 353 ? -38.281 9.320 -72.547 1.00 61.71 ? 353 LEU C CD2 1 +ATOM 5090 N N . CYS B 2 354 ? -41.124 13.317 -71.841 1.00 62.89 ? 354 CYS C N 1 +ATOM 5091 C CA . CYS B 2 354 ? -41.732 14.635 -71.809 1.00 61.78 ? 354 CYS C CA 1 +ATOM 5092 C C . CYS B 2 354 ? -40.653 15.705 -71.794 1.00 69.13 ? 354 CYS C C 1 +ATOM 5093 O O . CYS B 2 354 ? -39.569 15.506 -71.233 1.00 51.55 ? 354 CYS C O 1 +ATOM 5094 C CB . CYS B 2 354 ? -42.620 14.790 -70.593 1.00 56.69 ? 354 CYS C CB 1 +ATOM 5095 S SG . CYS B 2 354 ? -43.677 13.381 -70.302 1.00 53.57 ? 354 CYS C SG 1 +ATOM 5096 N N . GLY B 2 355 ? -40.945 16.824 -72.458 1.00 78.58 ? 355 GLY C N 1 +ATOM 5097 C CA . GLY B 2 355 ? -40.155 18.027 -72.336 1.00 73.36 ? 355 GLY C CA 1 +ATOM 5098 C C . GLY B 2 355 ? -40.768 19.005 -71.342 1.00 64.30 ? 355 GLY C C 1 +ATOM 5099 O O . GLY B 2 355 ? -41.819 18.774 -70.748 1.00 63.51 ? 355 GLY C O 1 +ATOM 5100 N N . LYS B 2 356 ? -40.092 20.139 -71.185 1.00 59.29 ? 356 LYS C N 1 +ATOM 5101 C CA . LYS B 2 356 ? -40.572 21.204 -70.311 1.00 62.33 ? 356 LYS C CA 1 +ATOM 5102 C C . LYS B 2 356 ? -40.560 22.512 -71.090 1.00 61.45 ? 356 LYS C C 1 +ATOM 5103 O O . LYS B 2 356 ? -39.568 23.252 -71.072 1.00 64.88 ? 356 LYS C O 1 +ATOM 5104 C CB . LYS B 2 356 ? -39.733 21.292 -69.038 1.00 69.38 ? 356 LYS C CB 1 +ATOM 5105 C CG . LYS B 2 356 ? -40.317 22.207 -67.961 1.00 84.89 ? 356 LYS C CG 1 +ATOM 5106 C CD . LYS B 2 356 ? -41.788 21.885 -67.679 1.00 76.42 ? 356 LYS C CD 1 +ATOM 5107 C CE . LYS B 2 356 ? -42.347 22.725 -66.530 1.00 68.62 ? 356 LYS C CE 1 +ATOM 5108 N NZ . LYS B 2 356 ? -42.910 21.885 -65.429 1.00 65.94 ? 356 LYS C NZ 1 +ATOM 5109 N N . PRO B 2 357 ? -41.652 22.828 -71.801 1.00 66.80 ? 357 PRO C N 1 +ATOM 5110 C CA . PRO B 2 357 ? -42.815 21.949 -71.961 1.00 69.29 ? 357 PRO C CA 1 +ATOM 5111 C C . PRO B 2 357 ? -42.807 21.173 -73.275 1.00 69.82 ? 357 PRO C C 1 +ATOM 5112 O O . PRO B 2 357 ? -43.669 20.308 -73.463 1.00 61.68 ? 357 PRO C O 1 +ATOM 5113 C CB . PRO B 2 357 ? -43.987 22.928 -71.931 1.00 64.95 ? 357 PRO C CB 1 +ATOM 5114 C CG . PRO B 2 357 ? -43.433 24.152 -72.582 1.00 82.33 ? 357 PRO C CG 1 +ATOM 5115 C CD . PRO B 2 357 ? -41.949 24.203 -72.242 1.00 81.64 ? 357 PRO C CD 1 +ATOM 5116 N N . ASP B 2 358 ? -41.858 21.478 -74.170 1.00 74.77 ? 358 ASP C N 1 +ATOM 5117 C CA . ASP B 2 358 ? -41.874 20.888 -75.505 1.00 73.49 ? 358 ASP C CA 1 +ATOM 5118 C C . ASP B 2 358 ? -40.466 20.825 -76.101 1.00 61.48 ? 358 ASP C C 1 +ATOM 5119 O O . ASP B 2 358 ? -40.275 21.047 -77.300 1.00 64.96 ? 358 ASP C O 1 +ATOM 5120 C CB . ASP B 2 358 ? -42.822 21.652 -76.435 1.00 74.87 ? 358 ASP C CB 1 +ATOM 5121 C CG . ASP B 2 358 ? -42.431 23.115 -76.605 1.00 81.81 ? 358 ASP C CG 1 +ATOM 5122 O OD1 . ASP B 2 358 ? -41.849 23.691 -75.658 1.00 77.23 ? 358 ASP C OD1 1 +ATOM 5123 O OD2 . ASP B 2 358 ? -42.736 23.696 -77.674 1.00 89.08 ? 358 ASP C OD2 1 +ATOM 5124 N N . GLN B 2 359 ? -39.471 20.500 -75.285 1.00 58.31 ? 359 GLN C N 1 +ATOM 5125 C CA . GLN B 2 359 ? -38.131 20.229 -75.795 1.00 66.69 ? 359 GLN C CA 1 +ATOM 5126 C C . GLN B 2 359 ? -37.576 19.022 -75.056 1.00 78.51 ? 359 GLN C C 1 +ATOM 5127 O O . GLN B 2 359 ? -37.611 18.985 -73.823 1.00 86.22 ? 359 GLN C O 1 +ATOM 5128 C CB . GLN B 2 359 ? -37.198 21.438 -75.647 1.00 71.96 ? 359 GLN C CB 1 +ATOM 5129 C CG . GLN B 2 359 ? -37.605 22.656 -76.478 1.00 70.36 ? 359 GLN C CG 1 +ATOM 5130 C CD . GLN B 2 359 ? -36.436 23.595 -76.746 1.00 73.65 ? 359 GLN C CD 1 +ATOM 5131 O OE1 . GLN B 2 359 ? -35.628 23.356 -77.644 1.00 71.52 ? 359 GLN C OE1 1 +ATOM 5132 N NE2 . GLN B 2 359 ? -36.349 24.673 -75.974 1.00 70.52 ? 359 GLN C NE2 1 +ATOM 5133 N N . ILE B 2 360 ? -37.067 18.039 -75.803 1.00 74.91 ? 360 ILE C N 1 +ATOM 5134 C CA . ILE B 2 360 ? -36.870 16.701 -75.247 1.00 68.73 ? 360 ILE C CA 1 +ATOM 5135 C C . ILE B 2 360 ? -35.402 16.282 -75.181 1.00 56.23 ? 360 ILE C C 1 +ATOM 5136 O O . ILE B 2 360 ? -35.033 15.477 -74.318 1.00 55.81 ? 360 ILE C O 1 +ATOM 5137 C CB . ILE B 2 360 ? -37.710 15.670 -76.022 1.00 52.98 ? 360 ILE C CB 1 +ATOM 5138 C CG1 . ILE B 2 360 ? -36.821 14.658 -76.738 1.00 50.06 ? 360 ILE C CG1 1 +ATOM 5139 C CG2 . ILE B 2 360 ? -38.584 16.362 -77.016 1.00 54.28 ? 360 ILE C CG2 1 +ATOM 5140 C CD1 . ILE B 2 360 ? -37.599 13.577 -77.434 1.00 62.48 ? 360 ILE C CD1 1 +ATOM 5141 N N . GLU B 2 361 ? -34.561 16.789 -76.092 1.00 50.53 ? 361 GLU C N 1 +ATOM 5142 C CA . GLU B 2 361 ? -33.131 16.462 -76.096 1.00 54.07 ? 361 GLU C CA 1 +ATOM 5143 C C . GLU B 2 361 ? -32.895 15.022 -76.547 1.00 59.66 ? 361 GLU C C 1 +ATOM 5144 O O . GLU B 2 361 ? -33.730 14.145 -76.302 1.00 58.90 ? 361 GLU C O 1 +ATOM 5145 C CB . GLU B 2 361 ? -32.515 16.710 -74.704 1.00 48.91 ? 361 GLU C CB 1 +ATOM 5146 C CG . GLU B 2 361 ? -31.056 16.296 -74.505 1.00 53.77 ? 361 GLU C CG 1 +ATOM 5147 C CD . GLU B 2 361 ? -30.561 16.525 -73.065 1.00 62.08 ? 361 GLU C CD 1 +ATOM 5148 O OE1 . GLU B 2 361 ? -29.810 15.670 -72.538 1.00 54.11 ? 361 GLU C OE1 1 +ATOM 5149 O OE2 . GLU B 2 361 ? -30.900 17.570 -72.465 1.00 65.99 ? 361 GLU C OE2 1 +ATOM 5150 N N . GLY B 2 362 ? -31.777 14.769 -77.218 1.00 65.44 ? 362 GLY C N 1 +ATOM 5151 C CA . GLY B 2 362 ? -31.475 13.433 -77.696 1.00 59.33 ? 362 GLY C CA 1 +ATOM 5152 C C . GLY B 2 362 ? -30.227 13.429 -78.554 1.00 54.90 ? 362 GLY C C 1 +ATOM 5153 O O . GLY B 2 362 ? -29.567 14.455 -78.745 1.00 54.46 ? 362 GLY C O 1 +ATOM 5154 N N . SER B 2 363 ? -29.908 12.238 -79.062 1.00 51.96 ? 363 SER C N 1 +ATOM 5155 C CA . SER B 2 363 ? -28.725 12.024 -79.883 1.00 50.29 ? 363 SER C CA 1 +ATOM 5156 C C . SER B 2 363 ? -29.112 11.560 -81.283 1.00 50.59 ? 363 SER C C 1 +ATOM 5157 O O . SER B 2 363 ? -30.102 10.844 -81.476 1.00 45.15 ? 363 SER C O 1 +ATOM 5158 C CB . SER B 2 363 ? -27.782 11.004 -79.243 1.00 46.63 ? 363 SER C CB 1 +ATOM 5159 O OG . SER B 2 363 ? -28.374 9.720 -79.215 1.00 52.14 ? 363 SER C OG 1 +ATOM 5160 N N . LEU B 2 364 ? -28.312 11.983 -82.260 1.00 47.70 ? 364 LEU C N 1 +ATOM 5161 C CA . LEU B 2 364 ? -28.493 11.646 -83.669 1.00 44.30 ? 364 LEU C CA 1 +ATOM 5162 C C . LEU B 2 364 ? -27.267 10.862 -84.132 1.00 52.22 ? 364 LEU C C 1 +ATOM 5163 O O . LEU B 2 364 ? -26.207 11.447 -84.376 1.00 52.64 ? 364 LEU C O 1 +ATOM 5164 C CB . LEU B 2 364 ? -28.689 12.896 -84.523 1.00 45.79 ? 364 LEU C CB 1 +ATOM 5165 C CG . LEU B 2 364 ? -30.075 13.531 -84.667 1.00 42.96 ? 364 LEU C CG 1 +ATOM 5166 C CD1 . LEU B 2 364 ? -31.079 12.514 -85.126 1.00 38.00 ? 364 LEU C CD1 1 +ATOM 5167 C CD2 . LEU B 2 364 ? -30.524 14.175 -83.370 1.00 60.95 ? 364 LEU C CD2 1 +ATOM 5168 N N . ALA B 2 365 ? -27.402 9.542 -84.223 1.00 54.03 ? 365 ALA C N 1 +ATOM 5169 C CA . ALA B 2 365 ? -26.346 8.681 -84.744 1.00 49.21 ? 365 ALA C CA 1 +ATOM 5170 C C . ALA B 2 365 ? -26.492 8.579 -86.260 1.00 44.52 ? 365 ALA C C 1 +ATOM 5171 O O . ALA B 2 365 ? -27.566 8.229 -86.758 1.00 40.93 ? 365 ALA C O 1 +ATOM 5172 C CB . ALA B 2 365 ? -26.399 7.301 -84.090 1.00 54.72 ? 365 ALA C CB 1 +ATOM 5173 N N . ALA B 2 366 ? -25.426 8.920 -86.985 1.00 48.00 ? 366 ALA C N 1 +ATOM 5174 C CA . ALA B 2 366 ? -25.438 8.891 -88.445 1.00 45.12 ? 366 ALA C CA 1 +ATOM 5175 C C . ALA B 2 366 ? -25.767 7.499 -88.976 1.00 43.90 ? 366 ALA C C 1 +ATOM 5176 O O . ALA B 2 366 ? -25.404 6.481 -88.383 1.00 50.53 ? 366 ALA C O 1 +ATOM 5177 C CB . ALA B 2 366 ? -24.082 9.333 -88.990 1.00 46.93 ? 366 ALA C CB 1 +ATOM 5178 N N . PHE B 2 367 ? -26.437 7.460 -90.126 1.00 41.10 ? 367 PHE C N 1 +ATOM 5179 C CA . PHE B 2 367 ? -26.921 6.206 -90.690 1.00 42.44 ? 367 PHE C CA 1 +ATOM 5180 C C . PHE B 2 367 ? -25.842 5.555 -91.545 1.00 42.24 ? 367 PHE C C 1 +ATOM 5181 O O . PHE B 2 367 ? -25.273 6.195 -92.435 1.00 38.00 ? 367 PHE C O 1 +ATOM 5182 C CB . PHE B 2 367 ? -28.184 6.434 -91.523 1.00 43.64 ? 367 PHE C CB 1 +ATOM 5183 C CG . PHE B 2 367 ? -29.329 5.530 -91.153 1.00 42.56 ? 367 PHE C CG 1 +ATOM 5184 C CD1 . PHE B 2 367 ? -29.100 4.312 -90.538 1.00 47.88 ? 367 PHE C CD1 1 +ATOM 5185 C CD2 . PHE B 2 367 ? -30.636 5.904 -91.416 1.00 42.97 ? 367 PHE C CD2 1 +ATOM 5186 C CE1 . PHE B 2 367 ? -30.156 3.485 -90.196 1.00 64.22 ? 367 PHE C CE1 1 +ATOM 5187 C CE2 . PHE B 2 367 ? -31.693 5.087 -91.074 1.00 39.12 ? 367 PHE C CE2 1 +ATOM 5188 C CZ . PHE B 2 367 ? -31.454 3.876 -90.464 1.00 49.32 ? 367 PHE C CZ 1 +ATOM 5189 N N . LEU B 2 368 ? -25.544 4.288 -91.246 1.00 45.90 ? 368 LEU C N 1 +ATOM 5190 C CA . LEU B 2 368 ? -24.674 3.487 -92.091 1.00 39.34 ? 368 LEU C CA 1 +ATOM 5191 C C . LEU B 2 368 ? -25.305 3.306 -93.473 1.00 41.04 ? 368 LEU C C 1 +ATOM 5192 O O . LEU B 2 368 ? -26.524 3.402 -93.623 1.00 44.23 ? 368 LEU C O 1 +ATOM 5193 C CB . LEU B 2 368 ? -24.398 2.137 -91.427 1.00 38.00 ? 368 LEU C CB 1 +ATOM 5194 C CG . LEU B 2 368 ? -23.379 2.176 -90.283 1.00 38.00 ? 368 LEU C CG 1 +ATOM 5195 C CD1 . LEU B 2 368 ? -23.150 0.798 -89.699 1.00 41.05 ? 368 LEU C CD1 1 +ATOM 5196 C CD2 . LEU B 2 368 ? -22.057 2.757 -90.757 1.00 38.00 ? 368 LEU C CD2 1 +ATOM 5197 N N . PRO B 2 369 ? -24.491 3.044 -94.501 1.00 42.77 ? 369 PRO C N 1 +ATOM 5198 C CA . PRO B 2 369 ? -25.029 2.974 -95.865 1.00 39.35 ? 369 PRO C CA 1 +ATOM 5199 C C . PRO B 2 369 ? -26.043 1.856 -96.011 1.00 41.76 ? 369 PRO C C 1 +ATOM 5200 O O . PRO B 2 369 ? -26.036 0.880 -95.256 1.00 43.52 ? 369 PRO C O 1 +ATOM 5201 C CB . PRO B 2 369 ? -23.790 2.716 -96.725 1.00 41.61 ? 369 PRO C CB 1 +ATOM 5202 C CG . PRO B 2 369 ? -22.833 2.077 -95.809 1.00 48.51 ? 369 PRO C CG 1 +ATOM 5203 C CD . PRO B 2 369 ? -23.058 2.705 -94.469 1.00 45.95 ? 369 PRO C CD 1 +ATOM 5204 N N . ASP B 2 370 ? -26.925 2.023 -96.998 1.00 43.15 ? 370 ASP C N 1 +ATOM 5205 C CA . ASP B 2 370 ? -28.049 1.113 -97.178 1.00 47.04 ? 370 ASP C CA 1 +ATOM 5206 C C . ASP B 2 370 ? -27.573 -0.320 -97.364 1.00 44.85 ? 370 ASP C C 1 +ATOM 5207 O O . ASP B 2 370 ? -26.736 -0.608 -98.224 1.00 40.93 ? 370 ASP C O 1 +ATOM 5208 C CB . ASP B 2 370 ? -28.896 1.550 -98.372 1.00 47.11 ? 370 ASP C CB 1 +ATOM 5209 C CG . ASP B 2 370 ? -30.220 0.815 -98.438 1.00 51.80 ? 370 ASP C CG 1 +ATOM 5210 O OD1 . ASP B 2 370 ? -30.648 0.298 -97.383 1.00 65.38 ? 370 ASP C OD1 1 +ATOM 5211 O OD2 . ASP B 2 370 ? -30.849 0.777 -99.517 1.00 42.03 ? 370 ASP C OD2 1 +ATOM 5212 N N . LEU B 2 371 ? -28.169 -1.231 -96.593 1.00 50.76 ? 371 LEU C N 1 +ATOM 5213 C CA . LEU B 2 371 ? -27.738 -2.621 -96.578 1.00 48.76 ? 371 LEU C CA 1 +ATOM 5214 C C . LEU B 2 371 ? -27.830 -3.288 -97.936 1.00 41.69 ? 371 LEU C C 1 +ATOM 5215 O O . LEU B 2 371 ? -27.355 -4.418 -98.077 1.00 45.40 ? 371 LEU C O 1 +ATOM 5216 C CB . LEU B 2 371 ? -28.550 -3.423 -95.564 1.00 51.21 ? 371 LEU C CB 1 +ATOM 5217 C CG . LEU B 2 371 ? -28.274 -3.121 -94.092 1.00 50.66 ? 371 LEU C CG 1 +ATOM 5218 C CD1 . LEU B 2 371 ? -29.154 -1.988 -93.573 1.00 54.48 ? 371 LEU C CD1 1 +ATOM 5219 C CD2 . LEU B 2 371 ? -28.429 -4.384 -93.257 1.00 48.63 ? 371 LEU C CD2 1 +ATOM 5220 N N . ALA B 2 372 ? -28.427 -2.634 -98.929 1.00 38.09 ? 372 ALA C N 1 +ATOM 5221 C CA . ALA B 2 372 ? -28.532 -3.248 -100.245 1.00 43.02 ? 372 ALA C CA 1 +ATOM 5222 C C . ALA B 2 372 ? -27.171 -3.316 -100.927 1.00 45.63 ? 372 ALA C C 1 +ATOM 5223 O O . ALA B 2 372 ? -26.790 -4.358 -101.472 1.00 44.80 ? 372 ALA C O 1 +ATOM 5224 C CB . ALA B 2 372 ? -29.536 -2.479 -101.100 1.00 43.46 ? 372 ALA C CB 1 +ATOM 5225 N N . LEU B 2 373 ? -26.417 -2.216 -100.900 1.00 46.48 ? 373 LEU C N 1 +ATOM 5226 C CA . LEU B 2 373 ? -25.091 -2.167 -101.503 1.00 49.52 ? 373 LEU C CA 1 +ATOM 5227 C C . LEU B 2 373 ? -23.966 -2.212 -100.476 1.00 52.59 ? 373 LEU C C 1 +ATOM 5228 O O . LEU B 2 373 ? -22.816 -1.922 -100.820 1.00 58.82 ? 373 LEU C O 1 +ATOM 5229 C CB . LEU B 2 373 ? -24.948 -0.922 -102.387 1.00 45.14 ? 373 LEU C CB 1 +ATOM 5230 C CG . LEU B 2 373 ? -25.653 0.388 -102.030 1.00 39.92 ? 373 LEU C CG 1 +ATOM 5231 C CD1 . LEU B 2 373 ? -25.271 0.854 -100.647 1.00 49.74 ? 373 LEU C CD1 1 +ATOM 5232 C CD2 . LEU B 2 373 ? -25.322 1.458 -103.059 1.00 38.00 ? 373 LEU C CD2 1 +ATOM 5233 N N . ALA B 2 374 ? -24.269 -2.554 -99.228 1.00 52.04 ? 374 ALA C N 1 +ATOM 5234 C CA . ALA B 2 374 ? -23.271 -2.651 -98.170 1.00 48.49 ? 374 ALA C CA 1 +ATOM 5235 C C . ALA B 2 374 ? -23.779 -3.619 -97.102 1.00 51.32 ? 374 ALA C C 1 +ATOM 5236 O O . ALA B 2 374 ? -23.995 -3.256 -95.946 1.00 50.07 ? 374 ALA C O 1 +ATOM 5237 C CB . ALA B 2 374 ? -22.961 -1.272 -97.590 1.00 46.82 ? 374 ALA C CB 1 +ATOM 5238 N N . LYS B 2 375 ? -23.995 -4.873 -97.505 1.00 50.73 ? 375 LYS C N 1 +ATOM 5239 C CA . LYS B 2 375 ? -24.469 -5.899 -96.583 1.00 47.63 ? 375 LYS C CA 1 +ATOM 5240 C C . LYS B 2 375 ? -23.537 -6.012 -95.382 1.00 45.74 ? 375 LYS C C 1 +ATOM 5241 O O . LYS B 2 375 ? -22.315 -5.904 -95.510 1.00 45.56 ? 375 LYS C O 1 +ATOM 5242 C CB . LYS B 2 375 ? -24.568 -7.254 -97.293 1.00 51.45 ? 375 LYS C CB 1 +ATOM 5243 C CG . LYS B 2 375 ? -25.901 -7.554 -97.989 1.00 59.86 ? 375 LYS C CG 1 +ATOM 5244 C CD . LYS B 2 375 ? -25.921 -7.063 -99.440 1.00 66.75 ? 375 LYS C CD 1 +ATOM 5245 C CE . LYS B 2 375 ? -27.217 -7.450 -100.152 1.00 62.87 ? 375 LYS C CE 1 +ATOM 5246 N NZ . LYS B 2 375 ? -28.430 -6.924 -99.459 1.00 66.81 ? 375 LYS C NZ 1 +ATOM 5247 N N . ARG B 2 376 ? -24.119 -6.235 -94.207 1.00 43.96 ? 376 ARG C N 1 +ATOM 5248 C CA . ARG B 2 376 ? -23.355 -6.337 -92.971 1.00 41.19 ? 376 ARG C CA 1 +ATOM 5249 C C . ARG B 2 376 ? -23.572 -7.710 -92.358 1.00 42.32 ? 376 ARG C C 1 +ATOM 5250 O O . ARG B 2 376 ? -24.705 -8.071 -92.022 1.00 38.00 ? 376 ARG C O 1 +ATOM 5251 C CB . ARG B 2 376 ? -23.769 -5.253 -91.981 1.00 39.46 ? 376 ARG C CB 1 +ATOM 5252 C CG . ARG B 2 376 ? -23.804 -3.881 -92.579 1.00 43.26 ? 376 ARG C CG 1 +ATOM 5253 C CD . ARG B 2 376 ? -23.784 -2.843 -91.493 1.00 40.56 ? 376 ARG C CD 1 +ATOM 5254 N NE . ARG B 2 376 ? -24.807 -1.838 -91.735 1.00 55.24 ? 376 ARG C NE 1 +ATOM 5255 C CZ . ARG B 2 376 ? -26.006 -1.846 -91.164 1.00 53.73 ? 376 ARG C CZ 1 +ATOM 5256 N NH1 . ARG B 2 376 ? -26.325 -2.813 -90.309 1.00 45.29 ? 376 ARG C NH1 1 +ATOM 5257 N NH2 . ARG B 2 376 ? -26.880 -0.885 -91.445 1.00 52.98 ? 376 ARG C NH2 1 +ATOM 5258 N N . LYS B 2 377 ? -22.488 -8.470 -92.211 1.00 45.63 ? 377 LYS C N 1 +ATOM 5259 C CA . LYS B 2 377 ? -22.552 -9.701 -91.442 1.00 47.99 ? 377 LYS C CA 1 +ATOM 5260 C C . LYS B 2 377 ? -22.856 -9.374 -89.992 1.00 44.39 ? 377 LYS C C 1 +ATOM 5261 O O . LYS B 2 377 ? -22.542 -8.292 -89.498 1.00 48.28 ? 377 LYS C O 1 +ATOM 5262 C CB . LYS B 2 377 ? -21.230 -10.464 -91.526 1.00 52.65 ? 377 LYS C CB 1 +ATOM 5263 C CG . LYS B 2 377 ? -21.305 -11.943 -91.140 1.00 53.68 ? 377 LYS C CG 1 +ATOM 5264 C CD . LYS B 2 377 ? -21.937 -12.775 -92.247 1.00 60.86 ? 377 LYS C CD 1 +ATOM 5265 C CE . LYS B 2 377 ? -21.442 -14.207 -92.210 1.00 53.29 ? 377 LYS C CE 1 +ATOM 5266 N NZ . LYS B 2 377 ? -21.757 -14.844 -90.906 1.00 55.07 ? 377 LYS C NZ 1 +ATOM 5267 N N . THR B 2 378 ? -23.444 -10.333 -89.291 1.00 48.50 ? 378 THR C N 1 +ATOM 5268 C CA . THR B 2 378 ? -23.774 -10.148 -87.883 1.00 51.96 ? 378 THR C CA 1 +ATOM 5269 C C . THR B 2 378 ? -23.321 -11.383 -87.119 1.00 51.13 ? 378 THR C C 1 +ATOM 5270 O O . THR B 2 378 ? -23.878 -12.471 -87.292 1.00 55.60 ? 378 THR C O 1 +ATOM 5271 C CB . THR B 2 378 ? -25.269 -9.881 -87.695 1.00 48.51 ? 378 THR C CB 1 +ATOM 5272 O OG1 . THR B 2 378 ? -25.628 -10.122 -86.330 1.00 43.07 ? 378 THR C OG1 1 +ATOM 5273 C CG2 . THR B 2 378 ? -26.105 -10.758 -88.634 1.00 50.30 ? 378 THR C CG2 1 +ATOM 5274 N N . TRP B 2 379 ? -22.322 -11.207 -86.266 1.00 48.60 ? 379 TRP C N 1 +ATOM 5275 C CA . TRP B 2 379 ? -21.686 -12.310 -85.569 1.00 48.56 ? 379 TRP C CA 1 +ATOM 5276 C C . TRP B 2 379 ? -22.129 -12.332 -84.116 1.00 50.89 ? 379 TRP C C 1 +ATOM 5277 O O . TRP B 2 379 ? -22.417 -11.291 -83.516 1.00 50.23 ? 379 TRP C O 1 +ATOM 5278 C CB . TRP B 2 379 ? -20.166 -12.200 -85.636 1.00 49.38 ? 379 TRP C CB 1 +ATOM 5279 C CG . TRP B 2 379 ? -19.625 -12.026 -87.011 1.00 48.23 ? 379 TRP C CG 1 +ATOM 5280 C CD1 . TRP B 2 379 ? -19.682 -10.903 -87.771 1.00 50.15 ? 379 TRP C CD1 1 +ATOM 5281 C CD2 . TRP B 2 379 ? -18.918 -12.998 -87.783 1.00 49.49 ? 379 TRP C CD2 1 +ATOM 5282 N NE1 . TRP B 2 379 ? -19.062 -11.113 -88.976 1.00 52.49 ? 379 TRP C NE1 1 +ATOM 5283 C CE2 . TRP B 2 379 ? -18.584 -12.395 -89.008 1.00 51.36 ? 379 TRP C CE2 1 +ATOM 5284 C CE3 . TRP B 2 379 ? -18.544 -14.324 -87.561 1.00 57.66 ? 379 TRP C CE3 1 +ATOM 5285 C CZ2 . TRP B 2 379 ? -17.893 -13.069 -90.008 1.00 55.57 ? 379 TRP C CZ2 1 +ATOM 5286 C CZ3 . TRP B 2 379 ? -17.857 -14.992 -88.554 1.00 65.42 ? 379 TRP C CZ3 1 +ATOM 5287 C CH2 . TRP B 2 379 ? -17.540 -14.365 -89.763 1.00 62.97 ? 379 TRP C CH2 1 +ATOM 5288 N N . ARG B 2 380 ? -22.176 -13.537 -83.562 1.00 49.99 ? 380 ARG C N 1 +ATOM 5289 C CA . ARG B 2 380 ? -22.581 -13.745 -82.181 1.00 51.44 ? 380 ARG C CA 1 +ATOM 5290 C C . ARG B 2 380 ? -21.337 -13.748 -81.300 1.00 50.34 ? 380 ARG C C 1 +ATOM 5291 O O . ARG B 2 380 ? -20.374 -14.477 -81.577 1.00 45.62 ? 380 ARG C O 1 +ATOM 5292 C CB . ARG B 2 380 ? -23.369 -15.050 -82.050 1.00 59.14 ? 380 ARG C CB 1 +ATOM 5293 C CG . ARG B 2 380 ? -23.673 -15.476 -80.621 1.00 66.82 ? 380 ARG C CG 1 +ATOM 5294 C CD . ARG B 2 380 ? -24.272 -16.881 -80.563 1.00 75.06 ? 380 ARG C CD 1 +ATOM 5295 N NE . ARG B 2 380 ? -25.244 -17.021 -79.478 1.00 86.56 ? 380 ARG C NE 1 +ATOM 5296 C CZ . ARG B 2 380 ? -24.976 -17.594 -78.306 1.00 80.72 ? 380 ARG C CZ 1 +ATOM 5297 N NH1 . ARG B 2 380 ? -23.762 -18.076 -78.069 1.00 77.56 ? 380 ARG C NH1 1 +ATOM 5298 N NH2 . ARG B 2 380 ? -25.919 -17.683 -77.372 1.00 76.01 ? 380 ARG C NH2 1 +ATOM 5299 N N . ASN B 2 381 ? -21.334 -12.890 -80.287 1.00 50.78 ? 381 ASN C N 1 +ATOM 5300 C CA . ASN B 2 381 ? -20.198 -12.801 -79.381 1.00 45.13 ? 381 ASN C CA 1 +ATOM 5301 C C . ASN B 2 381 ? -20.067 -14.103 -78.597 1.00 45.01 ? 381 ASN C C 1 +ATOM 5302 O O . ASN B 2 381 ? -21.053 -14.574 -78.014 1.00 44.46 ? 381 ASN C O 1 +ATOM 5303 C CB . ASN B 2 381 ? -20.375 -11.618 -78.430 1.00 42.06 ? 381 ASN C CB 1 +ATOM 5304 C CG . ASN B 2 381 ? -19.118 -11.301 -77.635 1.00 39.57 ? 381 ASN C CG 1 +ATOM 5305 O OD1 . ASN B 2 381 ? -18.298 -12.173 -77.360 1.00 41.34 ? 381 ASN C OD1 1 +ATOM 5306 N ND2 . ASN B 2 381 ? -18.968 -10.041 -77.258 1.00 39.40 ? 381 ASN C ND2 1 +ATOM 5307 N N . PRO B 2 382 ? -18.879 -14.707 -78.547 1.00 40.58 ? 382 PRO C N 1 +ATOM 5308 C CA . PRO B 2 382 ? -18.721 -15.918 -77.731 1.00 43.14 ? 382 PRO C CA 1 +ATOM 5309 C C . PRO B 2 382 ? -18.840 -15.669 -76.238 1.00 47.70 ? 382 PRO C C 1 +ATOM 5310 O O . PRO B 2 382 ? -19.062 -16.629 -75.491 1.00 58.21 ? 382 PRO C O 1 +ATOM 5311 C CB . PRO B 2 382 ? -17.320 -16.414 -78.109 1.00 41.27 ? 382 PRO C CB 1 +ATOM 5312 C CG . PRO B 2 382 ? -16.625 -15.216 -78.640 1.00 38.00 ? 382 PRO C CG 1 +ATOM 5313 C CD . PRO B 2 382 ? -17.674 -14.420 -79.341 1.00 38.00 ? 382 PRO C CD 1 +ATOM 5314 N N . TRP B 2 383 ? -18.709 -14.424 -75.777 1.00 44.23 ? 383 TRP C N 1 +ATOM 5315 C CA . TRP B 2 383 ? -18.952 -14.078 -74.383 1.00 42.70 ? 383 TRP C CA 1 +ATOM 5316 C C . TRP B 2 383 ? -20.323 -13.453 -74.182 1.00 43.64 ? 383 TRP C C 1 +ATOM 5317 O O . TRP B 2 383 ? -20.527 -12.710 -73.218 1.00 50.11 ? 383 TRP C O 1 +ATOM 5318 C CB . TRP B 2 383 ? -17.857 -13.149 -73.863 1.00 41.80 ? 383 TRP C CB 1 +ATOM 5319 C CG . TRP B 2 383 ? -16.532 -13.817 -73.769 1.00 44.20 ? 383 TRP C CG 1 +ATOM 5320 C CD1 . TRP B 2 383 ? -16.056 -14.542 -72.719 1.00 47.85 ? 383 TRP C CD1 1 +ATOM 5321 C CD2 . TRP B 2 383 ? -15.508 -13.843 -74.775 1.00 46.61 ? 383 TRP C CD2 1 +ATOM 5322 N NE1 . TRP B 2 383 ? -14.795 -15.012 -73.003 1.00 53.24 ? 383 TRP C NE1 1 +ATOM 5323 C CE2 . TRP B 2 383 ? -14.436 -14.596 -74.259 1.00 46.59 ? 383 TRP C CE2 1 +ATOM 5324 C CE3 . TRP B 2 383 ? -15.393 -13.299 -76.057 1.00 44.46 ? 383 TRP C CE3 1 +ATOM 5325 C CZ2 . TRP B 2 383 ? -13.266 -14.820 -74.982 1.00 43.72 ? 383 TRP C CZ2 1 +ATOM 5326 C CZ3 . TRP B 2 383 ? -14.232 -13.521 -76.771 1.00 40.69 ? 383 TRP C CZ3 1 +ATOM 5327 C CH2 . TRP B 2 383 ? -13.185 -14.274 -76.232 1.00 42.28 ? 383 TRP C CH2 1 +ATOM 5328 N N . ARG B 2 384 ? -21.261 -13.737 -75.078 1.00 43.66 ? 384 ARG C N 1 +ATOM 5329 C CA . ARG B 2 384 ? -22.603 -13.186 -74.966 1.00 50.26 ? 384 ARG C CA 1 +ATOM 5330 C C . ARG B 2 384 ? -23.280 -13.693 -73.701 1.00 48.79 ? 384 ARG C C 1 +ATOM 5331 O O . ARG B 2 384 ? -23.318 -14.897 -73.444 1.00 57.04 ? 384 ARG C O 1 +ATOM 5332 C CB . ARG B 2 384 ? -23.426 -13.572 -76.192 1.00 54.76 ? 384 ARG C CB 1 +ATOM 5333 C CG . ARG B 2 384 ? -24.900 -13.244 -76.085 1.00 57.62 ? 384 ARG C CG 1 +ATOM 5334 C CD . ARG B 2 384 ? -25.691 -13.998 -77.134 1.00 64.23 ? 384 ARG C CD 1 +ATOM 5335 N NE . ARG B 2 384 ? -27.016 -13.420 -77.352 1.00 72.08 ? 384 ARG C NE 1 +ATOM 5336 C CZ . ARG B 2 384 ? -28.153 -13.950 -76.913 1.00 65.14 ? 384 ARG C CZ 1 +ATOM 5337 N NH1 . ARG B 2 384 ? -28.137 -15.086 -76.228 1.00 57.94 ? 384 ARG C NH1 1 +ATOM 5338 N NH2 . ARG B 2 384 ? -29.308 -13.342 -77.168 1.00 57.85 ? 384 ARG C NH2 1 +ATOM 5339 N N . ARG B 2 385 ? -23.789 -12.767 -72.896 1.00 47.17 ? 385 ARG C N 1 +ATOM 5340 C CA . ARG B 2 385 ? -24.501 -13.155 -71.687 1.00 52.77 ? 385 ARG C CA 1 +ATOM 5341 C C . ARG B 2 385 ? -25.739 -13.978 -72.031 1.00 52.20 ? 385 ARG C C 1 +ATOM 5342 O O . ARG B 2 385 ? -26.314 -13.854 -73.115 1.00 52.75 ? 385 ARG C O 1 +ATOM 5343 C CB . ARG B 2 385 ? -24.873 -11.919 -70.872 1.00 59.23 ? 385 ARG C CB 1 +ATOM 5344 C CG . ARG B 2 385 ? -23.673 -11.294 -70.175 1.00 59.47 ? 385 ARG C CG 1 +ATOM 5345 C CD . ARG B 2 385 ? -23.930 -9.870 -69.743 1.00 55.43 ? 385 ARG C CD 1 +ATOM 5346 N NE . ARG B 2 385 ? -22.688 -9.105 -69.654 1.00 64.23 ? 385 ARG C NE 1 +ATOM 5347 C CZ . ARG B 2 385 ? -21.847 -9.134 -68.623 1.00 62.46 ? 385 ARG C CZ 1 +ATOM 5348 N NH1 . ARG B 2 385 ? -22.096 -9.901 -67.568 1.00 60.20 ? 385 ARG C NH1 1 +ATOM 5349 N NH2 . ARG B 2 385 ? -20.749 -8.390 -68.653 1.00 58.23 ? 385 ARG C NH2 1 +ATOM 5350 N N . SER B 2 386 ? -26.130 -14.853 -71.099 1.00 51.04 ? 386 SER C N 1 +ATOM 5351 C CA . SER B 2 386 ? -27.248 -15.759 -71.350 1.00 59.50 ? 386 SER C CA 1 +ATOM 5352 C C . SER B 2 386 ? -28.567 -15.029 -71.539 1.00 59.32 ? 386 SER C C 1 +ATOM 5353 O O . SER B 2 386 ? -29.498 -15.602 -72.114 1.00 68.02 ? 386 SER C O 1 +ATOM 5354 C CB . SER B 2 386 ? -27.396 -16.753 -70.198 1.00 69.68 ? 386 SER C CB 1 +ATOM 5355 O OG . SER B 2 386 ? -27.740 -16.087 -68.994 1.00 67.33 ? 386 SER C OG 1 +ATOM 5356 N N . TYR B 2 387 ? -28.667 -13.785 -71.075 1.00 57.94 ? 387 TYR C N 1 +ATOM 5357 C CA . TYR B 2 387 ? -29.895 -12.997 -71.173 1.00 62.91 ? 387 TYR C CA 1 +ATOM 5358 C C . TYR B 2 387 ? -31.085 -13.771 -70.611 1.00 65.86 ? 387 TYR C C 1 +ATOM 5359 O O . TYR B 2 387 ? -32.151 -13.872 -71.225 1.00 58.60 ? 387 TYR C O 1 +ATOM 5360 C CB . TYR B 2 387 ? -30.145 -12.554 -72.614 1.00 59.73 ? 387 TYR C CB 1 +ATOM 5361 C CG . TYR B 2 387 ? -29.115 -11.560 -73.100 1.00 60.46 ? 387 TYR C CG 1 +ATOM 5362 C CD1 . TYR B 2 387 ? -28.816 -10.420 -72.366 1.00 60.00 ? 387 TYR C CD1 1 +ATOM 5363 C CD2 . TYR B 2 387 ? -28.420 -11.777 -74.277 1.00 62.83 ? 387 TYR C CD2 1 +ATOM 5364 C CE1 . TYR B 2 387 ? -27.865 -9.520 -72.799 1.00 57.50 ? 387 TYR C CE1 1 +ATOM 5365 C CE2 . TYR B 2 387 ? -27.473 -10.885 -74.716 1.00 63.30 ? 387 TYR C CE2 1 +ATOM 5366 C CZ . TYR B 2 387 ? -27.196 -9.759 -73.979 1.00 59.30 ? 387 TYR C CZ 1 +ATOM 5367 O OH . TYR B 2 387 ? -26.244 -8.875 -74.435 1.00 63.53 ? 387 TYR C OH 1 +ATOM 5368 N N . HIS B 2 388 ? -30.879 -14.319 -69.415 1.00 69.36 ? 388 HIS C N 1 +ATOM 5369 C CA . HIS B 2 388 ? -31.879 -15.110 -68.709 1.00 73.47 ? 388 HIS C CA 1 +ATOM 5370 C C . HIS B 2 388 ? -31.500 -15.140 -67.238 1.00 73.74 ? 388 HIS C C 1 +ATOM 5371 O O . HIS B 2 388 ? -30.350 -15.438 -66.901 1.00 72.65 ? 388 HIS C O 1 +ATOM 5372 C CB . HIS B 2 388 ? -31.970 -16.535 -69.267 1.00 73.81 ? 388 HIS C CB 1 +ATOM 5373 C CG . HIS B 2 388 ? -32.977 -16.691 -70.363 1.00 79.37 ? 388 HIS C CG 1 +ATOM 5374 N ND1 . HIS B 2 388 ? -34.097 -15.893 -70.459 1.00 87.43 ? 388 HIS C ND1 1 +ATOM 5375 C CD2 . HIS B 2 388 ? -33.034 -17.546 -71.412 1.00 74.63 ? 388 HIS C CD2 1 +ATOM 5376 C CE1 . HIS B 2 388 ? -34.799 -16.248 -71.521 1.00 89.36 ? 388 HIS C CE1 1 +ATOM 5377 N NE2 . HIS B 2 388 ? -34.176 -17.249 -72.116 1.00 83.19 ? 388 HIS C NE2 1 +ATOM 5378 N N . LYS B 2 389 ? -32.444 -14.770 -66.375 1.00 79.16 ? 389 LYS C N 1 +ATOM 5379 C CA . LYS B 2 389 ? -32.209 -14.856 -64.940 1.00 78.77 ? 389 LYS C CA 1 +ATOM 5380 C C . LYS B 2 389 ? -31.994 -16.311 -64.528 1.00 88.79 ? 389 LYS C C 1 +ATOM 5381 O O . LYS B 2 389 ? -32.469 -17.243 -65.188 1.00 87.78 ? 389 LYS C O 1 +ATOM 5382 C CB . LYS B 2 389 ? -33.376 -14.241 -64.161 1.00 74.97 ? 389 LYS C CB 1 +ATOM 5383 C CG . LYS B 2 389 ? -34.619 -13.918 -64.997 1.00 80.02 ? 389 LYS C CG 1 +ATOM 5384 C CD . LYS B 2 389 ? -35.769 -13.418 -64.118 1.00 66.71 ? 389 LYS C CD 1 +ATOM 5385 C CE . LYS B 2 389 ? -36.900 -12.821 -64.945 1.00 64.09 ? 389 LYS C CE 1 +ATOM 5386 N NZ . LYS B 2 389 ? -36.469 -11.587 -65.660 1.00 65.14 ? 389 LYS C NZ 1 +ATOM 5387 N N . ARG B 2 390 ? -31.254 -16.495 -63.427 1.00 90.08 ? 390 ARG C N 1 +ATOM 5388 C CA . ARG B 2 390 ? -30.938 -17.803 -62.850 1.00 86.03 ? 390 ARG C CA 1 +ATOM 5389 C C . ARG B 2 390 ? -29.933 -18.559 -63.715 1.00 82.73 ? 390 ARG C C 1 +ATOM 5390 O O . ARG B 2 390 ? -28.868 -18.960 -63.233 1.00 83.85 ? 390 ARG C O 1 +ATOM 5391 C CB . ARG B 2 390 ? -32.206 -18.645 -62.645 1.00 84.88 ? 390 ARG C CB 1 +ATOM 5392 C CG . ARG B 2 390 ? -33.199 -18.083 -61.628 1.00 85.06 ? 390 ARG C CG 1 +ATOM 5393 C CD . ARG B 2 390 ? -34.585 -17.982 -62.251 1.00 86.16 ? 390 ARG C CD 1 +ATOM 5394 N NE . ARG B 2 390 ? -35.573 -17.388 -61.354 1.00 77.51 ? 390 ARG C NE 1 +ATOM 5395 C CZ . ARG B 2 390 ? -36.790 -17.006 -61.733 1.00 70.50 ? 390 ARG C CZ 1 +ATOM 5396 N NH1 . ARG B 2 390 ? -37.172 -17.144 -62.996 1.00 71.33 ? 390 ARG C NH1 1 +ATOM 5397 N NH2 . ARG B 2 390 ? -37.627 -16.480 -60.851 1.00 61.73 ? 390 ARG C NH2 1 +ATOM 5398 N N . LYS B 2 391 ? -30.271 -18.768 -64.984 1.00 79.83 ? 391 LYS C N 1 +ATOM 5399 C CA . LYS B 2 391 ? -29.465 -19.588 -65.883 1.00 72.57 ? 391 LYS C CA 1 +ATOM 5400 C C . LYS B 2 391 ? -28.127 -18.922 -66.197 1.00 71.94 ? 391 LYS C C 1 +ATOM 5401 O O . LYS B 2 391 ? -28.084 -17.794 -66.697 1.00 74.36 ? 391 LYS C O 1 +ATOM 5402 C CB . LYS B 2 391 ? -30.260 -19.839 -67.160 1.00 66.49 ? 391 LYS C CB 1 +ATOM 5403 C CG . LYS B 2 391 ? -31.737 -20.069 -66.855 1.00 77.13 ? 391 LYS C CG 1 +ATOM 5404 C CD . LYS B 2 391 ? -32.651 -19.775 -68.033 1.00 87.51 ? 391 LYS C CD 1 +ATOM 5405 C CE . LYS B 2 391 ? -33.882 -18.973 -67.591 1.00 85.42 ? 391 LYS C CE 1 +ATOM 5406 N NZ . LYS B 2 391 ? -34.549 -19.492 -66.358 1.00 79.44 ? 391 LYS C NZ 1 +ATOM 5407 N N . LYS B 2 392 ? -27.034 -19.640 -65.939 1.00 69.49 ? 392 LYS C N 1 +ATOM 5408 C CA . LYS B 2 392 ? -25.686 -19.106 -66.110 1.00 69.83 ? 392 LYS C CA 1 +ATOM 5409 C C . LYS B 2 392 ? -25.271 -19.146 -67.584 1.00 67.39 ? 392 LYS C C 1 +ATOM 5410 O O . LYS B 2 392 ? -26.078 -19.397 -68.484 1.00 64.84 ? 392 LYS C O 1 +ATOM 5411 C CB . LYS B 2 392 ? -24.704 -19.876 -65.230 1.00 72.71 ? 392 LYS C CB 1 +ATOM 5412 C CG . LYS B 2 392 ? -24.016 -19.044 -64.157 1.00 75.55 ? 392 LYS C CG 1 +ATOM 5413 C CD . LYS B 2 392 ? -22.881 -19.827 -63.495 1.00 88.95 ? 392 LYS C CD 1 +ATOM 5414 C CE . LYS B 2 392 ? -23.410 -20.949 -62.603 1.00 97.92 ? 392 LYS C CE 1 +ATOM 5415 N NZ . LYS B 2 392 ? -22.338 -21.648 -61.826 1.00 88.96 ? 392 LYS C NZ 1 +ATOM 5416 N N . ALA B 2 393 ? -23.981 -18.922 -67.840 1.00 65.91 ? 393 ALA C N 1 +ATOM 5417 C CA . ALA B 2 393 ? -23.440 -18.870 -69.191 1.00 59.61 ? 393 ALA C CA 1 +ATOM 5418 C C . ALA B 2 393 ? -22.145 -19.666 -69.246 1.00 58.27 ? 393 ALA C C 1 +ATOM 5419 O O . ALA B 2 393 ? -21.501 -19.909 -68.225 1.00 66.95 ? 393 ALA C O 1 +ATOM 5420 C CB . ALA B 2 393 ? -23.187 -17.427 -69.642 1.00 61.62 ? 393 ALA C CB 1 +ATOM 5421 N N . GLU B 2 394 ? -21.767 -20.066 -70.463 1.00 58.15 ? 394 GLU C N 1 +ATOM 5422 C CA . GLU B 2 394 ? -20.616 -20.949 -70.631 1.00 62.82 ? 394 GLU C CA 1 +ATOM 5423 C C . GLU B 2 394 ? -19.335 -20.291 -70.132 1.00 64.09 ? 394 GLU C C 1 +ATOM 5424 O O . GLU B 2 394 ? -18.588 -20.884 -69.344 1.00 65.03 ? 394 GLU C O 1 +ATOM 5425 C CB . GLU B 2 394 ? -20.478 -21.367 -72.097 1.00 63.46 ? 394 GLU C CB 1 +ATOM 5426 C CG . GLU B 2 394 ? -20.521 -22.882 -72.317 1.00 63.51 ? 394 GLU C CG 1 +ATOM 5427 C CD . GLU B 2 394 ? -19.250 -23.590 -71.869 1.00 70.40 ? 394 GLU C CD 1 +ATOM 5428 O OE1 . GLU B 2 394 ? -18.193 -23.372 -72.496 1.00 66.54 ? 394 GLU C OE1 1 +ATOM 5429 O OE2 . GLU B 2 394 ? -19.308 -24.366 -70.889 1.00 81.02 ? 394 GLU C OE2 1 +ATOM 5430 N N . TRP B 2 395 ? -19.061 -19.063 -70.583 1.00 66.07 ? 395 TRP C N 1 +ATOM 5431 C CA . TRP B 2 395 ? -17.838 -18.358 -70.199 1.00 66.24 ? 395 TRP C CA 1 +ATOM 5432 C C . TRP B 2 395 ? -17.780 -18.045 -68.705 1.00 58.03 ? 395 TRP C C 1 +ATOM 5433 O O . TRP B 2 395 ? -16.726 -17.623 -68.215 1.00 50.48 ? 395 TRP C O 1 +ATOM 5434 C CB . TRP B 2 395 ? -17.690 -17.077 -71.036 1.00 61.86 ? 395 TRP C CB 1 +ATOM 5435 C CG . TRP B 2 395 ? -18.888 -16.160 -70.991 1.00 63.04 ? 395 TRP C CG 1 +ATOM 5436 C CD1 . TRP B 2 395 ? -20.067 -16.312 -71.666 1.00 56.71 ? 395 TRP C CD1 1 +ATOM 5437 C CD2 . TRP B 2 395 ? -19.014 -14.949 -70.234 1.00 62.32 ? 395 TRP C CD2 1 +ATOM 5438 N NE1 . TRP B 2 395 ? -20.921 -15.276 -71.367 1.00 53.96 ? 395 TRP C NE1 1 +ATOM 5439 C CE2 . TRP B 2 395 ? -20.298 -14.427 -70.490 1.00 57.30 ? 395 TRP C CE2 1 +ATOM 5440 C CE3 . TRP B 2 395 ? -18.169 -14.260 -69.360 1.00 60.17 ? 395 TRP C CE3 1 +ATOM 5441 C CZ2 . TRP B 2 395 ? -20.753 -13.247 -69.905 1.00 58.18 ? 395 TRP C CZ2 1 +ATOM 5442 C CZ3 . TRP B 2 395 ? -18.623 -13.090 -68.780 1.00 55.39 ? 395 TRP C CZ3 1 +ATOM 5443 C CH2 . TRP B 2 395 ? -19.902 -12.595 -69.055 1.00 55.53 ? 395 TRP C CH2 1 +ATOM 5444 N N . GLU B 2 396 ? -18.874 -18.247 -67.977 1.00 55.26 ? 396 GLU C N 1 +ATOM 5445 C CA . GLU B 2 396 ? -18.927 -18.022 -66.541 1.00 58.79 ? 396 GLU C CA 1 +ATOM 5446 C C . GLU B 2 396 ? -18.623 -19.280 -65.734 1.00 62.22 ? 396 GLU C C 1 +ATOM 5447 O O . GLU B 2 396 ? -18.783 -19.272 -64.509 1.00 54.31 ? 396 GLU C O 1 +ATOM 5448 C CB . GLU B 2 396 ? -20.305 -17.488 -66.150 1.00 67.74 ? 396 GLU C CB 1 +ATOM 5449 C CG . GLU B 2 396 ? -20.629 -16.118 -66.709 1.00 66.99 ? 396 GLU C CG 1 +ATOM 5450 C CD . GLU B 2 396 ? -21.984 -15.617 -66.248 1.00 74.22 ? 396 GLU C CD 1 +ATOM 5451 O OE1 . GLU B 2 396 ? -22.766 -16.426 -65.703 1.00 67.95 ? 396 GLU C OE1 1 +ATOM 5452 O OE2 . GLU B 2 396 ? -22.254 -14.406 -66.403 1.00 77.44 ? 396 GLU C OE2 1 +ATOM 5453 N N . VAL B 2 397 ? -18.224 -20.366 -66.393 1.00 67.91 ? 397 VAL C N 1 +ATOM 5454 C CA . VAL B 2 397 ? -17.878 -21.600 -65.693 1.00 67.61 ? 397 VAL C CA 1 +ATOM 5455 C C . VAL B 2 397 ? -16.599 -22.247 -66.205 1.00 62.95 ? 397 VAL C C 1 +ATOM 5456 O O . VAL B 2 397 ? -15.949 -22.998 -65.453 1.00 59.77 ? 397 VAL C O 1 +ATOM 5457 C CB . VAL B 2 397 ? -19.055 -22.600 -65.758 1.00 70.70 ? 397 VAL C CB 1 +ATOM 5458 C CG1 . VAL B 2 397 ? -19.155 -23.221 -67.148 1.00 71.77 ? 397 VAL C CG1 1 +ATOM 5459 C CG2 . VAL B 2 397 ? -18.918 -23.674 -64.678 1.00 69.08 ? 397 VAL C CG2 1 +ATOM 5460 N N . ASP B 2 398 ? -16.170 -21.987 -67.438 1.00 58.08 ? 398 ASP C N 1 +ATOM 5461 C CA . ASP B 2 398 ? -14.931 -22.552 -67.958 1.00 60.06 ? 398 ASP C CA 1 +ATOM 5462 C C . ASP B 2 398 ? -13.877 -21.462 -67.979 1.00 64.84 ? 398 ASP C C 1 +ATOM 5463 O O . ASP B 2 398 ? -13.950 -20.563 -68.830 1.00 71.68 ? 398 ASP C O 1 +ATOM 5464 C CB . ASP B 2 398 ? -15.130 -23.113 -69.368 1.00 66.69 ? 398 ASP C CB 1 +ATOM 5465 C CG . ASP B 2 398 ? -13.911 -23.886 -69.869 1.00 80.45 ? 398 ASP C CG 1 +ATOM 5466 O OD1 . ASP B 2 398 ? -12.784 -23.348 -69.808 1.00 76.16 ? 398 ASP C OD1 1 +ATOM 5467 O OD2 . ASP B 2 398 ? -14.081 -25.027 -70.351 1.00 86.96 ? 398 ASP C OD2 1 +ATOM 5468 N N . PRO B 2 399 ? -12.863 -21.511 -67.113 1.00 66.34 ? 399 PRO C N 1 +ATOM 5469 C CA . PRO B 2 399 ? -11.845 -20.451 -67.118 1.00 71.14 ? 399 PRO C CA 1 +ATOM 5470 C C . PRO B 2 399 ? -10.916 -20.526 -68.310 1.00 76.48 ? 399 PRO C C 1 +ATOM 5471 O O . PRO B 2 399 ? -10.167 -19.571 -68.551 1.00 81.25 ? 399 PRO C O 1 +ATOM 5472 C CB . PRO B 2 399 ? -11.090 -20.683 -65.806 1.00 64.77 ? 399 PRO C CB 1 +ATOM 5473 C CG . PRO B 2 399 ? -11.218 -22.144 -65.575 1.00 79.24 ? 399 PRO C CG 1 +ATOM 5474 C CD . PRO B 2 399 ? -12.565 -22.559 -66.124 1.00 70.84 ? 399 PRO C CD 1 +ATOM 5475 N N . ASP B 2 400 ? -10.929 -21.633 -69.050 1.00 72.23 ? 400 ASP C N 1 +ATOM 5476 C CA . ASP B 2 400 ? -10.123 -21.799 -70.251 1.00 79.73 ? 400 ASP C CA 1 +ATOM 5477 C C . ASP B 2 400 ? -10.944 -21.612 -71.523 1.00 78.25 ? 400 ASP C C 1 +ATOM 5478 O O . ASP B 2 400 ? -10.542 -22.091 -72.588 1.00 81.68 ? 400 ASP C O 1 +ATOM 5479 C CB . ASP B 2 400 ? -9.464 -23.176 -70.237 1.00 80.89 ? 400 ASP C CB 1 +ATOM 5480 C CG . ASP B 2 400 ? -8.653 -23.416 -68.976 1.00 92.70 ? 400 ASP C CG 1 +ATOM 5481 O OD1 . ASP B 2 400 ? -8.239 -22.431 -68.324 1.00 96.42 ? 400 ASP C OD1 1 +ATOM 5482 O OD2 . ASP B 2 400 ? -8.463 -24.591 -68.609 1.00 98.92 ? 400 ASP C OD2 1 +ATOM 5483 N N . TYR B 2 401 ? -12.095 -20.941 -71.415 1.00 70.56 ? 401 TYR C N 1 +ATOM 5484 C CA . TYR B 2 401 ? -12.992 -20.728 -72.548 1.00 66.30 ? 401 TYR C CA 1 +ATOM 5485 C C . TYR B 2 401 ? -12.239 -20.261 -73.790 1.00 65.84 ? 401 TYR C C 1 +ATOM 5486 O O . TYR B 2 401 ? -12.460 -20.777 -74.892 1.00 63.44 ? 401 TYR C O 1 +ATOM 5487 C CB . TYR B 2 401 ? -14.066 -19.712 -72.152 1.00 67.43 ? 401 TYR C CB 1 +ATOM 5488 C CG . TYR B 2 401 ? -15.202 -19.531 -73.136 1.00 67.08 ? 401 TYR C CG 1 +ATOM 5489 C CD1 . TYR B 2 401 ? -15.019 -18.843 -74.330 1.00 64.52 ? 401 TYR C CD1 1 +ATOM 5490 C CD2 . TYR B 2 401 ? -16.469 -20.029 -72.855 1.00 59.95 ? 401 TYR C CD2 1 +ATOM 5491 C CE1 . TYR B 2 401 ? -16.058 -18.675 -75.223 1.00 52.34 ? 401 TYR C CE1 1 +ATOM 5492 C CE2 . TYR B 2 401 ? -17.514 -19.858 -73.738 1.00 53.52 ? 401 TYR C CE2 1 +ATOM 5493 C CZ . TYR B 2 401 ? -17.300 -19.182 -74.920 1.00 48.17 ? 401 TYR C CZ 1 +ATOM 5494 O OH . TYR B 2 401 ? -18.332 -19.009 -75.806 1.00 45.25 ? 401 TYR C OH 1 +ATOM 5495 N N . CYS B 2 402 ? -11.345 -19.279 -73.630 1.00 72.05 ? 402 CYS C N 1 +ATOM 5496 C CA . CYS B 2 402 ? -10.664 -18.702 -74.786 1.00 76.97 ? 402 CYS C CA 1 +ATOM 5497 C C . CYS B 2 402 ? -9.824 -19.736 -75.524 1.00 82.50 ? 402 CYS C C 1 +ATOM 5498 O O . CYS B 2 402 ? -9.684 -19.659 -76.750 1.00 84.17 ? 402 CYS C O 1 +ATOM 5499 C CB . CYS B 2 402 ? -9.786 -17.524 -74.351 1.00 78.94 ? 402 CYS C CB 1 +ATOM 5500 S SG . CYS B 2 402 ? -8.919 -16.678 -75.720 1.00 87.37 ? 402 CYS C SG 1 +ATOM 5501 N N . ASP B 2 403 ? -9.283 -20.726 -74.807 1.00 80.02 ? 403 ASP C N 1 +ATOM 5502 C CA . ASP B 2 403 ? -8.492 -21.764 -75.457 1.00 74.10 ? 403 ASP C CA 1 +ATOM 5503 C C . ASP B 2 403 ? -9.341 -22.648 -76.354 1.00 76.70 ? 403 ASP C C 1 +ATOM 5504 O O . ASP B 2 403 ? -8.802 -23.304 -77.250 1.00 77.08 ? 403 ASP C O 1 +ATOM 5505 C CB . ASP B 2 403 ? -7.785 -22.620 -74.410 1.00 72.19 ? 403 ASP C CB 1 +ATOM 5506 C CG . ASP B 2 403 ? -6.956 -21.793 -73.451 1.00 86.54 ? 403 ASP C CG 1 +ATOM 5507 O OD1 . ASP B 2 403 ? -6.619 -20.640 -73.798 1.00 83.93 ? 403 ASP C OD1 1 +ATOM 5508 O OD2 . ASP B 2 403 ? -6.639 -22.302 -72.352 1.00 88.03 ? 403 ASP C OD2 1 +ATOM 5509 N N . GLU B 2 404 ? -10.655 -22.660 -76.145 1.00 75.59 ? 404 GLU C N 1 +ATOM 5510 C CA . GLU B 2 404 ? -11.563 -23.358 -77.042 1.00 71.39 ? 404 GLU C CA 1 +ATOM 5511 C C . GLU B 2 404 ? -12.085 -22.445 -78.133 1.00 69.91 ? 404 GLU C C 1 +ATOM 5512 O O . GLU B 2 404 ? -12.323 -22.898 -79.257 1.00 74.97 ? 404 GLU C O 1 +ATOM 5513 C CB . GLU B 2 404 ? -12.738 -23.939 -76.250 1.00 69.93 ? 404 GLU C CB 1 +ATOM 5514 C CG . GLU B 2 404 ? -13.351 -25.185 -76.865 1.00 77.26 ? 404 GLU C CG 1 +ATOM 5515 C CD . GLU B 2 404 ? -14.438 -25.794 -75.995 1.00 84.61 ? 404 GLU C CD 1 +ATOM 5516 O OE1 . GLU B 2 404 ? -15.590 -25.313 -76.052 1.00 83.98 ? 404 GLU C OE1 1 +ATOM 5517 O OE2 . GLU B 2 404 ? -14.138 -26.760 -75.258 1.00 77.72 ? 404 GLU C OE2 1 +ATOM 5518 N N . VAL B 2 405 ? -12.226 -21.153 -77.836 1.00 68.00 ? 405 VAL C N 1 +ATOM 5519 C CA . VAL B 2 405 ? -12.752 -20.219 -78.823 1.00 68.83 ? 405 VAL C CA 1 +ATOM 5520 C C . VAL B 2 405 ? -11.681 -19.735 -79.783 1.00 68.19 ? 405 VAL C C 1 +ATOM 5521 O O . VAL B 2 405 ? -12.012 -19.157 -80.824 1.00 78.90 ? 405 VAL C O 1 +ATOM 5522 C CB . VAL B 2 405 ? -13.429 -19.032 -78.114 1.00 67.49 ? 405 VAL C CB 1 +ATOM 5523 C CG1 . VAL B 2 405 ? -12.416 -17.941 -77.794 1.00 68.11 ? 405 VAL C CG1 1 +ATOM 5524 C CG2 . VAL B 2 405 ? -14.588 -18.499 -78.939 1.00 59.91 ? 405 VAL C CG2 1 +ATOM 5525 N N . LYS B 2 406 ? -10.409 -19.976 -79.494 1.00 62.17 ? 406 LYS C N 1 +ATOM 5526 C CA . LYS B 2 406 ? -9.373 -19.655 -80.460 1.00 65.16 ? 406 LYS C CA 1 +ATOM 5527 C C . LYS B 2 406 ? -9.134 -20.795 -81.438 1.00 68.51 ? 406 LYS C C 1 +ATOM 5528 O O . LYS B 2 406 ? -8.169 -20.753 -82.210 1.00 68.81 ? 406 LYS C O 1 +ATOM 5529 C CB . LYS B 2 406 ? -8.073 -19.276 -79.744 1.00 71.42 ? 406 LYS C CB 1 +ATOM 5530 C CG . LYS B 2 406 ? -7.420 -20.400 -78.977 1.00 76.98 ? 406 LYS C CG 1 +ATOM 5531 C CD . LYS B 2 406 ? -6.104 -19.943 -78.363 1.00 77.65 ? 406 LYS C CD 1 +ATOM 5532 C CE . LYS B 2 406 ? -6.316 -18.777 -77.398 1.00 75.92 ? 406 LYS C CE 1 +ATOM 5533 N NZ . LYS B 2 406 ? -5.124 -17.886 -77.276 1.00 66.94 ? 406 LYS C NZ 1 +ATOM 5534 N N . GLN B 2 407 ? -10.017 -21.788 -81.454 1.00 66.78 ? 407 GLN C N 1 +ATOM 5535 C CA . GLN B 2 407 ? -9.944 -22.869 -82.420 1.00 74.67 ? 407 GLN C CA 1 +ATOM 5536 C C . GLN B 2 407 ? -11.040 -22.798 -83.472 1.00 80.00 ? 407 GLN C C 1 +ATOM 5537 O O . GLN B 2 407 ? -10.960 -23.517 -84.475 1.00 88.30 ? 407 GLN C O 1 +ATOM 5538 C CB . GLN B 2 407 ? -10.019 -24.226 -81.702 1.00 79.65 ? 407 GLN C CB 1 +ATOM 5539 C CG . GLN B 2 407 ? -9.208 -25.325 -82.365 1.00 87.60 ? 407 GLN C CG 1 +ATOM 5540 C CD . GLN B 2 407 ? -7.985 -25.715 -81.557 1.00 83.22 ? 407 GLN C CD 1 +ATOM 5541 O OE1 . GLN B 2 407 ? -7.855 -25.341 -80.388 1.00 74.00 ? 407 GLN C OE1 1 +ATOM 5542 N NE2 . GLN B 2 407 ? -7.080 -26.473 -82.175 1.00 76.47 ? 407 GLN C NE2 1 +ATOM 5543 N N . THR B 2 408 ? -12.049 -21.947 -83.275 1.00 77.14 ? 408 THR C N 1 +ATOM 5544 C CA . THR B 2 408 ? -13.140 -21.801 -84.226 1.00 84.07 ? 408 THR C CA 1 +ATOM 5545 C C . THR B 2 408 ? -12.639 -21.242 -85.563 1.00 75.89 ? 408 THR C C 1 +ATOM 5546 O O . THR B 2 408 ? -11.589 -20.595 -85.625 1.00 71.38 ? 408 THR C O 1 +ATOM 5547 C CB . THR B 2 408 ? -14.219 -20.906 -83.624 1.00 75.49 ? 408 THR C CB 1 +ATOM 5548 O OG1 . THR B 2 408 ? -13.681 -20.244 -82.475 1.00 70.08 ? 408 THR C OG1 1 +ATOM 5549 C CG2 . THR B 2 408 ? -15.406 -21.747 -83.192 1.00 75.79 ? 408 THR C CG2 1 +ATOM 5550 N N . PRO B 2 409 ? -13.392 -21.466 -86.642 1.00 73.14 ? 409 PRO C N 1 +ATOM 5551 C CA . PRO B 2 409 ? -12.921 -21.073 -87.984 1.00 81.84 ? 409 PRO C CA 1 +ATOM 5552 C C . PRO B 2 409 ? -12.572 -19.597 -88.098 1.00 87.74 ? 409 PRO C C 1 +ATOM 5553 O O . PRO B 2 409 ? -11.527 -19.274 -88.685 1.00 87.55 ? 409 PRO C O 1 +ATOM 5554 C CB . PRO B 2 409 ? -14.099 -21.444 -88.906 1.00 85.19 ? 409 PRO C CB 1 +ATOM 5555 C CG . PRO B 2 409 ? -15.239 -21.825 -87.993 1.00 83.38 ? 409 PRO C CG 1 +ATOM 5556 C CD . PRO B 2 409 ? -14.605 -22.300 -86.726 1.00 72.53 ? 409 PRO C CD 1 +ATOM 5557 N N . PRO B 2 410 ? -13.362 -18.666 -87.555 1.00 82.35 ? 410 PRO C N 1 +ATOM 5558 C CA . PRO B 2 410 ? -13.033 -17.250 -87.784 1.00 68.14 ? 410 PRO C CA 1 +ATOM 5559 C C . PRO B 2 410 ? -12.197 -16.587 -86.698 1.00 63.21 ? 410 PRO C C 1 +ATOM 5560 O O . PRO B 2 410 ? -11.779 -15.444 -86.906 1.00 57.07 ? 410 PRO C O 1 +ATOM 5561 C CB . PRO B 2 410 ? -14.425 -16.610 -87.845 1.00 50.18 ? 410 PRO C CB 1 +ATOM 5562 C CG . PRO B 2 410 ? -15.279 -17.463 -86.943 1.00 50.16 ? 410 PRO C CG 1 +ATOM 5563 C CD . PRO B 2 410 ? -14.550 -18.757 -86.682 1.00 64.10 ? 410 PRO C CD 1 +ATOM 5564 N N . TYR B 2 411 ? -11.885 -17.271 -85.598 1.00 63.70 ? 411 TYR C N 1 +ATOM 5565 C CA . TYR B 2 411 ? -11.162 -16.655 -84.496 1.00 60.46 ? 411 TYR C CA 1 +ATOM 5566 C C . TYR B 2 411 ? -9.733 -17.158 -84.378 1.00 60.88 ? 411 TYR C C 1 +ATOM 5567 O O . TYR B 2 411 ? -9.028 -16.762 -83.444 1.00 60.23 ? 411 TYR C O 1 +ATOM 5568 C CB . TYR B 2 411 ? -11.888 -16.893 -83.167 1.00 51.30 ? 411 TYR C CB 1 +ATOM 5569 C CG . TYR B 2 411 ? -13.215 -16.182 -82.998 1.00 46.74 ? 411 TYR C CG 1 +ATOM 5570 C CD1 . TYR B 2 411 ? -14.005 -15.846 -84.089 1.00 53.12 ? 411 TYR C CD1 1 +ATOM 5571 C CD2 . TYR B 2 411 ? -13.690 -15.878 -81.738 1.00 48.60 ? 411 TYR C CD2 1 +ATOM 5572 C CE1 . TYR B 2 411 ? -15.220 -15.215 -83.926 1.00 48.16 ? 411 TYR C CE1 1 +ATOM 5573 C CE2 . TYR B 2 411 ? -14.902 -15.253 -81.567 1.00 47.95 ? 411 TYR C CE2 1 +ATOM 5574 C CZ . TYR B 2 411 ? -15.664 -14.922 -82.660 1.00 42.94 ? 411 TYR C CZ 1 +ATOM 5575 O OH . TYR B 2 411 ? -16.876 -14.299 -82.478 1.00 44.16 ? 411 TYR C OH 1 +ATOM 5576 N N . ASP B 2 412 ? -9.280 -18.000 -85.301 1.00 61.90 ? 412 ASP C N 1 +ATOM 5577 C CA . ASP B 2 412 ? -7.887 -18.418 -85.364 1.00 59.34 ? 412 ASP C CA 1 +ATOM 5578 C C . ASP B 2 412 ? -7.217 -17.852 -86.615 1.00 65.31 ? 412 ASP C C 1 +ATOM 5579 O O . ASP B 2 412 ? -6.309 -18.461 -87.183 1.00 67.61 ? 412 ASP C O 1 +ATOM 5580 C CB . ASP B 2 412 ? -7.770 -19.944 -85.302 1.00 62.07 ? 412 ASP C CB 1 +ATOM 5581 C CG . ASP B 2 412 ? -8.388 -20.632 -86.506 1.00 81.66 ? 412 ASP C CG 1 +ATOM 5582 O OD1 . ASP B 2 412 ? -9.284 -20.033 -87.141 1.00 79.89 ? 412 ASP C OD1 1 +ATOM 5583 O OD2 . ASP B 2 412 ? -8.000 -21.783 -86.804 1.00 89.51 ? 412 ASP C OD2 1 +ATOM 5584 N N . ARG B 2 413 ? -7.671 -16.679 -87.040 1.00 67.06 ? 413 ARG C N 1 +ATOM 5585 C CA . ARG B 2 413 ? -7.077 -15.928 -88.138 1.00 64.36 ? 413 ARG C CA 1 +ATOM 5586 C C . ARG B 2 413 ? -7.197 -14.458 -87.759 1.00 72.58 ? 413 ARG C C 1 +ATOM 5587 O O . ARG B 2 413 ? -7.267 -14.104 -86.578 1.00 77.95 ? 413 ARG C O 1 +ATOM 5588 C CB . ARG B 2 413 ? -7.753 -16.279 -89.476 1.00 60.57 ? 413 ARG C CB 1 +ATOM 5589 C CG . ARG B 2 413 ? -6.798 -16.744 -90.550 1.00 58.40 ? 413 ARG C CG 1 +ATOM 5590 C CD . ARG B 2 413 ? -7.461 -17.787 -91.425 1.00 72.41 ? 413 ARG C CD 1 +ATOM 5591 N NE . ARG B 2 413 ? -6.499 -18.487 -92.273 1.00 92.12 ? 413 ARG C NE 1 +ATOM 5592 C CZ . ARG B 2 413 ? -6.756 -19.619 -92.924 1.00 95.47 ? 413 ARG C CZ 1 +ATOM 5593 N NH1 . ARG B 2 413 ? -7.951 -20.195 -92.827 1.00 89.59 ? 413 ARG C NH1 1 +ATOM 5594 N NH2 . ARG B 2 413 ? -5.811 -20.181 -93.669 1.00 90.79 ? 413 ARG C NH2 1 +ATOM 5595 N N . GLY B 2 414 ? -7.206 -13.577 -88.755 1.00 72.84 ? 414 GLY C N 1 +ATOM 5596 C CA . GLY B 2 414 ? -7.280 -12.164 -88.422 1.00 76.90 ? 414 GLY C CA 1 +ATOM 5597 C C . GLY B 2 414 ? -6.053 -11.695 -87.635 1.00 80.01 ? 414 GLY C C 1 +ATOM 5598 O O . GLY B 2 414 ? -5.042 -12.396 -87.569 1.00 78.40 ? 414 GLY C O 1 +ATOM 5599 N N . THR B 2 415 ? -6.126 -10.501 -87.015 1.00 72.64 ? 415 THR C N 1 +ATOM 5600 C CA . THR B 2 415 ? -7.168 -9.437 -86.964 1.00 67.26 ? 415 THR C CA 1 +ATOM 5601 C C . THR B 2 415 ? -8.344 -9.751 -86.040 1.00 64.33 ? 415 THR C C 1 +ATOM 5602 O O . THR B 2 415 ? -8.644 -8.958 -85.151 1.00 66.83 ? 415 THR C O 1 +ATOM 5603 C CB . THR B 2 415 ? -7.743 -9.030 -88.356 1.00 75.70 ? 415 THR C CB 1 +ATOM 5604 O OG1 . THR B 2 415 ? -6.704 -9.068 -89.342 1.00 83.45 ? 415 THR C OG1 1 +ATOM 5605 C CG2 . THR B 2 415 ? -8.317 -7.621 -88.293 1.00 67.53 ? 415 THR C CG2 1 +ATOM 5606 N N . ARG B 2 416 ? -9.003 -10.890 -86.215 1.00 62.60 ? 416 ARG C N 1 +ATOM 5607 C CA . ARG B 2 416 ? -10.036 -11.240 -85.259 1.00 56.66 ? 416 ARG C CA 1 +ATOM 5608 C C . ARG B 2 416 ? -9.391 -11.592 -83.919 1.00 59.27 ? 416 ARG C C 1 +ATOM 5609 O O . ARG B 2 416 ? -8.163 -11.652 -83.792 1.00 58.64 ? 416 ARG C O 1 +ATOM 5610 C CB . ARG B 2 416 ? -10.895 -12.384 -85.787 1.00 56.85 ? 416 ARG C CB 1 +ATOM 5611 C CG . ARG B 2 416 ? -12.259 -12.460 -85.124 1.00 56.77 ? 416 ARG C CG 1 +ATOM 5612 C CD . ARG B 2 416 ? -12.998 -11.140 -85.224 1.00 53.53 ? 416 ARG C CD 1 +ATOM 5613 N NE . ARG B 2 416 ? -14.158 -11.257 -86.103 1.00 53.30 ? 416 ARG C NE 1 +ATOM 5614 C CZ . ARG B 2 416 ? -14.183 -10.855 -87.370 1.00 56.90 ? 416 ARG C CZ 1 +ATOM 5615 N NH1 . ARG B 2 416 ? -13.107 -10.291 -87.910 1.00 57.93 ? 416 ARG C NH1 1 +ATOM 5616 N NH2 . ARG B 2 416 ? -15.286 -11.013 -88.096 1.00 49.19 ? 416 ARG C NH2 1 +ATOM 5617 N N . LEU B 2 417 ? -10.238 -11.820 -82.909 1.00 62.09 ? 417 LEU C N 1 +ATOM 5618 C CA . LEU B 2 417 ? -9.836 -11.888 -81.503 1.00 64.30 ? 417 LEU C CA 1 +ATOM 5619 C C . LEU B 2 417 ? -9.260 -10.547 -81.075 1.00 61.56 ? 417 LEU C C 1 +ATOM 5620 O O . LEU B 2 417 ? -9.756 -9.918 -80.135 1.00 57.83 ? 417 LEU C O 1 +ATOM 5621 C CB . LEU B 2 417 ? -8.814 -13.000 -81.239 1.00 64.27 ? 417 LEU C CB 1 +ATOM 5622 C CG . LEU B 2 417 ? -9.267 -14.346 -80.671 1.00 58.08 ? 417 LEU C CG 1 +ATOM 5623 C CD1 . LEU B 2 417 ? -8.072 -15.277 -80.586 1.00 58.80 ? 417 LEU C CD1 1 +ATOM 5624 C CD2 . LEU B 2 417 ? -9.925 -14.187 -79.311 1.00 42.35 ? 417 LEU C CD2 1 +ATOM 5625 N N . LEU B 2 418 ? -8.206 -10.117 -81.771 1.00 60.45 ? 418 LEU C N 1 +ATOM 5626 C CA . LEU B 2 418 ? -7.642 -8.792 -81.548 1.00 62.95 ? 418 LEU C CA 1 +ATOM 5627 C C . LEU B 2 418 ? -8.710 -7.719 -81.712 1.00 66.07 ? 418 LEU C C 1 +ATOM 5628 O O . LEU B 2 418 ? -8.787 -6.775 -80.917 1.00 69.22 ? 418 LEU C O 1 +ATOM 5629 C CB . LEU B 2 418 ? -6.485 -8.547 -82.519 1.00 62.01 ? 418 LEU C CB 1 +ATOM 5630 C CG . LEU B 2 418 ? -5.122 -9.220 -82.313 1.00 57.70 ? 418 LEU C CG 1 +ATOM 5631 C CD1 . LEU B 2 418 ? -4.432 -8.642 -81.096 1.00 64.76 ? 418 LEU C CD1 1 +ATOM 5632 C CD2 . LEU B 2 418 ? -5.208 -10.743 -82.229 1.00 53.59 ? 418 LEU C CD2 1 +ATOM 5633 N N . ASP B 2 419 ? -9.519 -7.827 -82.767 1.00 59.33 ? 419 ASP C N 1 +ATOM 5634 C CA . ASP B 2 419 ? -10.638 -6.910 -82.934 1.00 58.20 ? 419 ASP C CA 1 +ATOM 5635 C C . ASP B 2 419 ? -11.558 -6.947 -81.720 1.00 63.39 ? 419 ASP C C 1 +ATOM 5636 O O . ASP B 2 419 ? -11.977 -5.900 -81.211 1.00 61.80 ? 419 ASP C O 1 +ATOM 5637 C CB . ASP B 2 419 ? -11.406 -7.259 -84.206 1.00 65.84 ? 419 ASP C CB 1 +ATOM 5638 C CG . ASP B 2 419 ? -10.712 -6.756 -85.452 1.00 79.09 ? 419 ASP C CG 1 +ATOM 5639 O OD1 . ASP B 2 419 ? -9.922 -5.789 -85.344 1.00 75.77 ? 419 ASP C OD1 1 +ATOM 5640 O OD2 . ASP B 2 419 ? -10.951 -7.334 -86.533 1.00 82.42 ? 419 ASP C OD2 1 +ATOM 5641 N N . ILE B 2 420 ? -11.898 -8.154 -81.257 1.00 61.55 ? 420 ILE C N 1 +ATOM 5642 C CA . ILE B 2 420 ? -12.728 -8.314 -80.063 1.00 57.32 ? 420 ILE C CA 1 +ATOM 5643 C C . ILE B 2 420 ? -12.062 -7.687 -78.843 1.00 56.81 ? 420 ILE C C 1 +ATOM 5644 O O . ILE B 2 420 ? -12.729 -7.074 -78.000 1.00 53.30 ? 420 ILE C O 1 +ATOM 5645 C CB . ILE B 2 420 ? -13.034 -9.805 -79.852 1.00 50.35 ? 420 ILE C CB 1 +ATOM 5646 C CG1 . ILE B 2 420 ? -13.673 -10.362 -81.124 1.00 50.13 ? 420 ILE C CG1 1 +ATOM 5647 C CG2 . ILE B 2 420 ? -13.953 -9.994 -78.664 1.00 49.71 ? 420 ILE C CG2 1 +ATOM 5648 C CD1 . ILE B 2 420 ? -13.706 -11.858 -81.188 1.00 58.01 ? 420 ILE C CD1 1 +ATOM 5649 N N . MET B 2 421 ? -10.742 -7.857 -78.716 1.00 59.04 ? 421 MET C N 1 +ATOM 5650 C CA . MET B 2 421 ? -10.000 -7.253 -77.612 1.00 59.28 ? 421 MET C CA 1 +ATOM 5651 C C . MET B 2 421 ? -10.118 -5.732 -77.635 1.00 57.16 ? 421 MET C C 1 +ATOM 5652 O O . MET B 2 421 ? -10.376 -5.099 -76.603 1.00 50.83 ? 421 MET C O 1 +ATOM 5653 C CB . MET B 2 421 ? -8.535 -7.687 -77.689 1.00 59.45 ? 421 MET C CB 1 +ATOM 5654 C CG . MET B 2 421 ? -8.313 -9.167 -77.422 1.00 51.94 ? 421 MET C CG 1 +ATOM 5655 S SD . MET B 2 421 ? -8.985 -9.713 -75.843 1.00 49.24 ? 421 MET C SD 1 +ATOM 5656 C CE . MET B 2 421 ? -10.244 -10.864 -76.382 1.00 54.62 ? 421 MET C CE 1 +ATOM 5657 N N . ASP B 2 422 ? -9.925 -5.128 -78.810 1.00 57.91 ? 422 ASP C N 1 +ATOM 5658 C CA . ASP B 2 422 ? -10.121 -3.690 -78.945 1.00 57.43 ? 422 ASP C CA 1 +ATOM 5659 C C . ASP B 2 422 ? -11.537 -3.288 -78.557 1.00 61.92 ? 422 ASP C C 1 +ATOM 5660 O O . ASP B 2 422 ? -11.752 -2.195 -78.019 1.00 57.24 ? 422 ASP C O 1 +ATOM 5661 C CB . ASP B 2 422 ? -9.823 -3.264 -80.383 1.00 58.65 ? 422 ASP C CB 1 +ATOM 5662 C CG . ASP B 2 422 ? -8.360 -3.421 -80.745 1.00 63.05 ? 422 ASP C CG 1 +ATOM 5663 O OD1 . ASP B 2 422 ? -7.580 -3.855 -79.872 1.00 62.68 ? 422 ASP C OD1 1 +ATOM 5664 O OD2 . ASP B 2 422 ? -7.992 -3.119 -81.900 1.00 69.03 ? 422 ASP C OD2 1 +ATOM 5665 N N . MET B 2 423 ? -12.500 -4.187 -78.745 1.00 59.04 ? 423 MET C N 1 +ATOM 5666 C CA . MET B 2 423 ? -13.887 -3.893 -78.425 1.00 49.85 ? 423 MET C CA 1 +ATOM 5667 C C . MET B 2 423 ? -14.204 -4.135 -76.960 1.00 49.26 ? 423 MET C C 1 +ATOM 5668 O O . MET B 2 423 ? -14.857 -3.303 -76.324 1.00 50.94 ? 423 MET C O 1 +ATOM 5669 C CB . MET B 2 423 ? -14.816 -4.743 -79.293 1.00 44.71 ? 423 MET C CB 1 +ATOM 5670 C CG . MET B 2 423 ? -16.197 -4.922 -78.691 1.00 52.43 ? 423 MET C CG 1 +ATOM 5671 S SD . MET B 2 423 ? -17.213 -6.107 -79.579 1.00 38.00 ? 423 MET C SD 1 +ATOM 5672 C CE . MET B 2 423 ? -17.919 -5.046 -80.828 1.00 48.12 ? 423 MET C CE 1 +ATOM 5673 N N . THR B 2 424 ? -13.738 -5.248 -76.399 1.00 48.92 ? 424 THR C N 1 +ATOM 5674 C CA . THR B 2 424 ? -14.067 -5.534 -75.009 1.00 57.10 ? 424 THR C CA 1 +ATOM 5675 C C . THR B 2 424 ? -13.390 -4.545 -74.065 1.00 57.08 ? 424 THR C C 1 +ATOM 5676 O O . THR B 2 424 ? -13.930 -4.241 -72.993 1.00 53.13 ? 424 THR C O 1 +ATOM 5677 C CB . THR B 2 424 ? -13.701 -6.980 -74.669 1.00 54.48 ? 424 THR C CB 1 +ATOM 5678 O OG1 . THR B 2 424 ? -14.096 -7.274 -73.323 1.00 57.46 ? 424 THR C OG1 1 +ATOM 5679 C CG2 . THR B 2 424 ? -12.211 -7.216 -74.828 1.00 50.83 ? 424 THR C CG2 1 +ATOM 5680 N N . ILE B 2 425 ? -12.239 -3.999 -74.457 1.00 53.01 ? 425 ILE C N 1 +ATOM 5681 C CA . ILE B 2 425 ? -11.663 -2.906 -73.685 1.00 50.20 ? 425 ILE C CA 1 +ATOM 5682 C C . ILE B 2 425 ? -12.563 -1.684 -73.768 1.00 53.90 ? 425 ILE C C 1 +ATOM 5683 O O . ILE B 2 425 ? -12.854 -1.040 -72.752 1.00 53.62 ? 425 ILE C O 1 +ATOM 5684 C CB . ILE B 2 425 ? -10.241 -2.602 -74.183 1.00 42.56 ? 425 ILE C CB 1 +ATOM 5685 C CG1 . ILE B 2 425 ? -9.331 -3.794 -73.913 1.00 40.76 ? 425 ILE C CG1 1 +ATOM 5686 C CG2 . ILE B 2 425 ? -9.691 -1.349 -73.526 1.00 42.44 ? 425 ILE C CG2 1 +ATOM 5687 C CD1 . ILE B 2 425 ? -7.926 -3.576 -74.361 1.00 51.19 ? 425 ILE C CD1 1 +ATOM 5688 N N . PHE B 2 426 ? -13.069 -1.390 -74.970 1.00 51.81 ? 426 PHE C N 1 +ATOM 5689 C CA . PHE B 2 426 ? -14.008 -0.289 -75.163 1.00 46.67 ? 426 PHE C CA 1 +ATOM 5690 C C . PHE B 2 426 ? -15.239 -0.450 -74.273 1.00 50.15 ? 426 PHE C C 1 +ATOM 5691 O O . PHE B 2 426 ? -15.615 0.476 -73.546 1.00 49.84 ? 426 PHE C O 1 +ATOM 5692 C CB . PHE B 2 426 ? -14.389 -0.221 -76.647 1.00 45.59 ? 426 PHE C CB 1 +ATOM 5693 C CG . PHE B 2 426 ? -15.212 0.982 -77.035 1.00 52.47 ? 426 PHE C CG 1 +ATOM 5694 C CD1 . PHE B 2 426 ? -15.546 1.967 -76.121 1.00 57.01 ? 426 PHE C CD1 1 +ATOM 5695 C CD2 . PHE B 2 426 ? -15.698 1.094 -78.326 1.00 53.75 ? 426 PHE C CD2 1 +ATOM 5696 C CE1 . PHE B 2 426 ? -16.321 3.048 -76.495 1.00 59.29 ? 426 PHE C CE1 1 +ATOM 5697 C CE2 . PHE B 2 426 ? -16.476 2.173 -78.705 1.00 51.79 ? 426 PHE C CE2 1 +ATOM 5698 C CZ . PHE B 2 426 ? -16.788 3.150 -77.788 1.00 52.70 ? 426 PHE C CZ 1 +ATOM 5699 N N . ASP B 2 427 ? -15.882 -1.621 -74.320 1.00 53.81 ? 427 ASP C N 1 +ATOM 5700 C CA . ASP B 2 427 ? -17.120 -1.820 -73.566 1.00 56.58 ? 427 ASP C CA 1 +ATOM 5701 C C . ASP B 2 427 ? -16.889 -1.722 -72.065 1.00 54.94 ? 427 ASP C C 1 +ATOM 5702 O O . ASP B 2 427 ? -17.791 -1.312 -71.323 1.00 48.02 ? 427 ASP C O 1 +ATOM 5703 C CB . ASP B 2 427 ? -17.736 -3.176 -73.909 1.00 59.47 ? 427 ASP C CB 1 +ATOM 5704 C CG . ASP B 2 427 ? -18.331 -3.214 -75.300 1.00 58.47 ? 427 ASP C CG 1 +ATOM 5705 O OD1 . ASP B 2 427 ? -18.810 -2.163 -75.775 1.00 58.40 ? 427 ASP C OD1 1 +ATOM 5706 O OD2 . ASP B 2 427 ? -18.303 -4.295 -75.925 1.00 56.13 ? 427 ASP C OD2 1 +ATOM 5707 N N . PHE B 2 428 ? -15.703 -2.122 -71.597 1.00 56.19 ? 428 PHE C N 1 +ATOM 5708 C CA . PHE B 2 428 ? -15.406 -2.031 -70.172 1.00 55.84 ? 428 PHE C CA 1 +ATOM 5709 C C . PHE B 2 428 ? -15.212 -0.584 -69.738 1.00 56.42 ? 428 PHE C C 1 +ATOM 5710 O O . PHE B 2 428 ? -15.645 -0.197 -68.646 1.00 61.78 ? 428 PHE C O 1 +ATOM 5711 C CB . PHE B 2 428 ? -14.171 -2.859 -69.832 1.00 49.52 ? 428 PHE C CB 1 +ATOM 5712 C CG . PHE B 2 428 ? -13.806 -2.814 -68.380 1.00 48.63 ? 428 PHE C CG 1 +ATOM 5713 C CD1 . PHE B 2 428 ? -14.548 -3.515 -67.449 1.00 51.43 ? 428 PHE C CD1 1 +ATOM 5714 C CD2 . PHE B 2 428 ? -12.724 -2.075 -67.945 1.00 52.77 ? 428 PHE C CD2 1 +ATOM 5715 C CE1 . PHE B 2 428 ? -14.221 -3.475 -66.112 1.00 56.14 ? 428 PHE C CE1 1 +ATOM 5716 C CE2 . PHE B 2 428 ? -12.387 -2.034 -66.607 1.00 53.09 ? 428 PHE C CE2 1 +ATOM 5717 C CZ . PHE B 2 428 ? -13.138 -2.734 -65.689 1.00 55.45 ? 428 PHE C CZ 1 +ATOM 5718 N N . LEU B 2 429 ? -14.561 0.228 -70.573 1.00 48.02 ? 429 LEU C N 1 +ATOM 5719 C CA . LEU B 2 429 ? -14.407 1.638 -70.241 1.00 43.26 ? 429 LEU C CA 1 +ATOM 5720 C C . LEU B 2 429 ? -15.757 2.318 -70.076 1.00 46.25 ? 429 LEU C C 1 +ATOM 5721 O O . LEU B 2 429 ? -15.888 3.249 -69.276 1.00 48.23 ? 429 LEU C O 1 +ATOM 5722 C CB . LEU B 2 429 ? -13.583 2.340 -71.316 1.00 43.69 ? 429 LEU C CB 1 +ATOM 5723 C CG . LEU B 2 429 ? -12.165 1.800 -71.457 1.00 38.59 ? 429 LEU C CG 1 +ATOM 5724 C CD1 . LEU B 2 429 ? -11.404 2.530 -72.547 1.00 38.00 ? 429 LEU C CD1 1 +ATOM 5725 C CD2 . LEU B 2 429 ? -11.458 1.931 -70.133 1.00 48.36 ? 429 LEU C CD2 1 +ATOM 5726 N N . MET B 2 430 ? -16.772 1.853 -70.803 1.00 45.68 ? 430 MET C N 1 +ATOM 5727 C CA . MET B 2 430 ? -18.111 2.412 -70.694 1.00 48.78 ? 430 MET C CA 1 +ATOM 5728 C C . MET B 2 430 ? -18.987 1.693 -69.679 1.00 47.13 ? 430 MET C C 1 +ATOM 5729 O O . MET B 2 430 ? -19.931 2.297 -69.155 1.00 46.98 ? 430 MET C O 1 +ATOM 5730 C CB . MET B 2 430 ? -18.814 2.371 -72.054 1.00 52.30 ? 430 MET C CB 1 +ATOM 5731 C CG . MET B 2 430 ? -18.045 3.006 -73.192 1.00 48.92 ? 430 MET C CG 1 +ATOM 5732 S SD . MET B 2 430 ? -19.100 3.165 -74.642 1.00 49.86 ? 430 MET C SD 1 +ATOM 5733 C CE . MET B 2 430 ? -19.475 1.462 -75.010 1.00 55.90 ? 430 MET C CE 1 +ATOM 5734 N N . GLY B 2 431 ? -18.711 0.426 -69.394 1.00 46.16 ? 431 GLY C N 1 +ATOM 5735 C CA . GLY B 2 431 ? -19.640 -0.351 -68.605 1.00 51.24 ? 431 GLY C CA 1 +ATOM 5736 C C . GLY B 2 431 ? -20.762 -0.942 -69.421 1.00 61.84 ? 431 GLY C C 1 +ATOM 5737 O O . GLY B 2 431 ? -21.807 -1.291 -68.863 1.00 59.86 ? 431 GLY C O 1 +ATOM 5738 N N . ASN B 2 432 ? -20.586 -1.035 -70.739 1.00 65.29 ? 432 ASN C N 1 +ATOM 5739 C CA . ASN B 2 432 ? -21.614 -1.548 -71.641 1.00 58.35 ? 432 ASN C CA 1 +ATOM 5740 C C . ASN B 2 432 ? -21.519 -3.064 -71.671 1.00 61.96 ? 432 ASN C C 1 +ATOM 5741 O O . ASN B 2 432 ? -20.730 -3.634 -72.430 1.00 58.15 ? 432 ASN C O 1 +ATOM 5742 C CB . ASN B 2 432 ? -21.438 -0.983 -73.044 1.00 55.11 ? 432 ASN C CB 1 +ATOM 5743 C CG . ASN B 2 432 ? -22.355 -1.650 -74.050 1.00 58.95 ? 432 ASN C CG 1 +ATOM 5744 O OD1 . ASN B 2 432 ? -23.530 -1.877 -73.769 1.00 62.30 ? 432 ASN C OD1 1 +ATOM 5745 N ND2 . ASN B 2 432 ? -21.819 -1.990 -75.218 1.00 55.38 ? 432 ASN C ND2 1 +ATOM 5746 N N . MET B 2 433 ? -22.345 -3.728 -70.864 1.00 56.14 ? 433 MET C N 1 +ATOM 5747 C CA . MET B 2 433 ? -22.370 -5.182 -70.824 1.00 57.62 ? 433 MET C CA 1 +ATOM 5748 C C . MET B 2 433 ? -23.461 -5.768 -71.710 1.00 52.22 ? 433 MET C C 1 +ATOM 5749 O O . MET B 2 433 ? -23.888 -6.904 -71.487 1.00 58.50 ? 433 MET C O 1 +ATOM 5750 C CB . MET B 2 433 ? -22.511 -5.672 -69.380 1.00 63.38 ? 433 MET C CB 1 +ATOM 5751 C CG . MET B 2 433 ? -23.400 -4.822 -68.492 1.00 62.56 ? 433 MET C CG 1 +ATOM 5752 S SD . MET B 2 433 ? -23.398 -5.415 -66.784 1.00 53.94 ? 433 MET C SD 1 +ATOM 5753 C CE . MET B 2 433 ? -24.134 -4.009 -65.944 1.00 65.35 ? 433 MET C CE 1 +ATOM 5754 N N . ASP B 2 434 ? -23.912 -5.022 -72.716 1.00 54.26 ? 434 ASP C N 1 +ATOM 5755 C CA . ASP B 2 434 ? -24.950 -5.472 -73.635 1.00 57.39 ? 434 ASP C CA 1 +ATOM 5756 C C . ASP B 2 434 ? -24.383 -5.797 -75.018 1.00 58.24 ? 434 ASP C C 1 +ATOM 5757 O O . ASP B 2 434 ? -25.090 -5.709 -76.026 1.00 50.38 ? 434 ASP C O 1 +ATOM 5758 C CB . ASP B 2 434 ? -26.053 -4.418 -73.730 1.00 62.50 ? 434 ASP C CB 1 +ATOM 5759 C CG . ASP B 2 434 ? -27.360 -4.978 -74.263 1.00 68.52 ? 434 ASP C CG 1 +ATOM 5760 O OD1 . ASP B 2 434 ? -27.575 -6.200 -74.142 1.00 72.63 ? 434 ASP C OD1 1 +ATOM 5761 O OD2 . ASP B 2 434 ? -28.180 -4.195 -74.794 1.00 72.84 ? 434 ASP C OD2 1 +ATOM 5762 N N . ARG B 2 435 ? -23.105 -6.191 -75.074 1.00 63.96 ? 435 ARG C N 1 +ATOM 5763 C CA . ARG B 2 435 ? -22.428 -6.493 -76.338 1.00 57.38 ? 435 ARG C CA 1 +ATOM 5764 C C . ARG B 2 435 ? -22.591 -7.975 -76.654 1.00 53.04 ? 435 ARG C C 1 +ATOM 5765 O O . ARG B 2 435 ? -21.718 -8.806 -76.401 1.00 52.27 ? 435 ARG C O 1 +ATOM 5766 C CB . ARG B 2 435 ? -20.953 -6.109 -76.271 1.00 53.33 ? 435 ARG C CB 1 +ATOM 5767 C CG . ARG B 2 435 ? -20.215 -6.268 -77.597 1.00 44.84 ? 435 ARG C CG 1 +ATOM 5768 C CD . ARG B 2 435 ? -20.636 -5.180 -78.570 1.00 49.88 ? 435 ARG C CD 1 +ATOM 5769 N NE . ARG B 2 435 ? -20.220 -3.858 -78.112 1.00 53.46 ? 435 ARG C NE 1 +ATOM 5770 C CZ . ARG B 2 435 ? -20.467 -2.730 -78.766 1.00 46.97 ? 435 ARG C CZ 1 +ATOM 5771 N NH1 . ARG B 2 435 ? -21.135 -2.761 -79.911 1.00 41.46 ? 435 ARG C NH1 1 +ATOM 5772 N NH2 . ARG B 2 435 ? -20.047 -1.574 -78.271 1.00 49.76 ? 435 ARG C NH2 1 +ATOM 5773 N N . HIS B 2 436 ? -23.726 -8.298 -77.268 1.00 55.13 ? 436 HIS C N 1 +ATOM 5774 C CA . HIS B 2 436 ? -24.036 -9.665 -77.653 1.00 56.92 ? 436 HIS C CA 1 +ATOM 5775 C C . HIS B 2 436 ? -23.804 -9.945 -79.131 1.00 60.80 ? 436 HIS C C 1 +ATOM 5776 O O . HIS B 2 436 ? -23.861 -11.108 -79.538 1.00 60.69 ? 436 HIS C O 1 +ATOM 5777 C CB . HIS B 2 436 ? -25.497 -9.984 -77.305 1.00 58.70 ? 436 HIS C CB 1 +ATOM 5778 C CG . HIS B 2 436 ? -26.490 -8.997 -77.848 1.00 66.33 ? 436 HIS C CG 1 +ATOM 5779 N ND1 . HIS B 2 436 ? -26.138 -7.968 -78.694 1.00 67.95 ? 436 HIS C ND1 1 +ATOM 5780 C CD2 . HIS B 2 436 ? -27.828 -8.888 -77.665 1.00 73.36 ? 436 HIS C CD2 1 +ATOM 5781 C CE1 . HIS B 2 436 ? -27.213 -7.268 -79.009 1.00 73.44 ? 436 HIS C CE1 1 +ATOM 5782 N NE2 . HIS B 2 436 ? -28.252 -7.805 -78.396 1.00 79.56 ? 436 HIS C NE2 1 +ATOM 5783 N N . HIS B 2 437 ? -23.504 -8.922 -79.927 1.00 63.10 ? 437 HIS C N 1 +ATOM 5784 C CA . HIS B 2 437 ? -23.372 -9.053 -81.370 1.00 58.99 ? 437 HIS C CA 1 +ATOM 5785 C C . HIS B 2 437 ? -22.404 -7.995 -81.869 1.00 54.69 ? 437 HIS C C 1 +ATOM 5786 O O . HIS B 2 437 ? -22.323 -6.896 -81.313 1.00 57.03 ? 437 HIS C O 1 +ATOM 5787 C CB . HIS B 2 437 ? -24.711 -8.873 -82.101 1.00 59.68 ? 437 HIS C CB 1 +ATOM 5788 C CG . HIS B 2 437 ? -25.673 -10.003 -81.912 1.00 61.89 ? 437 HIS C CG 1 +ATOM 5789 N ND1 . HIS B 2 437 ? -25.269 -11.289 -81.624 1.00 60.01 ? 437 HIS C ND1 1 +ATOM 5790 C CD2 . HIS B 2 437 ? -27.025 -10.037 -81.969 1.00 63.50 ? 437 HIS C CD2 1 +ATOM 5791 C CE1 . HIS B 2 437 ? -26.331 -12.067 -81.514 1.00 61.36 ? 437 HIS C CE1 1 +ATOM 5792 N NE2 . HIS B 2 437 ? -27.410 -11.332 -81.718 1.00 66.19 ? 437 HIS C NE2 1 +ATOM 5793 N N . TYR B 2 438 ? -21.662 -8.333 -82.918 1.00 43.84 ? 438 TYR C N 1 +ATOM 5794 C CA . TYR B 2 438 ? -20.783 -7.364 -83.560 1.00 43.75 ? 438 TYR C CA 1 +ATOM 5795 C C . TYR B 2 438 ? -20.911 -7.530 -85.062 1.00 41.67 ? 438 TYR C C 1 +ATOM 5796 O O . TYR B 2 438 ? -20.701 -8.626 -85.586 1.00 48.94 ? 438 TYR C O 1 +ATOM 5797 C CB . TYR B 2 438 ? -19.332 -7.519 -83.100 1.00 44.46 ? 438 TYR C CB 1 +ATOM 5798 C CG . TYR B 2 438 ? -18.729 -8.871 -83.353 1.00 43.50 ? 438 TYR C CG 1 +ATOM 5799 C CD1 . TYR B 2 438 ? -18.962 -9.922 -82.486 1.00 48.78 ? 438 TYR C CD1 1 +ATOM 5800 C CD2 . TYR B 2 438 ? -17.880 -9.081 -84.425 1.00 44.38 ? 438 TYR C CD2 1 +ATOM 5801 C CE1 . TYR B 2 438 ? -18.400 -11.153 -82.702 1.00 52.92 ? 438 TYR C CE1 1 +ATOM 5802 C CE2 . TYR B 2 438 ? -17.309 -10.306 -84.651 1.00 47.43 ? 438 TYR C CE2 1 +ATOM 5803 C CZ . TYR B 2 438 ? -17.568 -11.340 -83.786 1.00 54.01 ? 438 TYR C CZ 1 +ATOM 5804 O OH . TYR B 2 438 ? -16.999 -12.570 -84.012 1.00 61.32 ? 438 TYR C OH 1 +ATOM 5805 N N . GLU B 2 439 ? -21.318 -6.466 -85.740 1.00 38.00 ? 439 GLU C N 1 +ATOM 5806 C CA . GLU B 2 439 ? -21.527 -6.555 -87.170 1.00 38.00 ? 439 GLU C CA 1 +ATOM 5807 C C . GLU B 2 439 ? -20.209 -6.346 -87.923 1.00 39.63 ? 439 GLU C C 1 +ATOM 5808 O O . GLU B 2 439 ? -19.195 -5.924 -87.359 1.00 38.31 ? 439 GLU C O 1 +ATOM 5809 C CB . GLU B 2 439 ? -22.592 -5.546 -87.607 1.00 39.91 ? 439 GLU C CB 1 +ATOM 5810 C CG . GLU B 2 439 ? -24.017 -5.863 -87.112 1.00 38.00 ? 439 GLU C CG 1 +ATOM 5811 C CD . GLU B 2 439 ? -25.063 -4.864 -87.627 1.00 44.19 ? 439 GLU C CD 1 +ATOM 5812 O OE1 . GLU B 2 439 ? -25.104 -4.609 -88.852 1.00 41.41 ? 439 GLU C OE1 1 +ATOM 5813 O OE2 . GLU B 2 439 ? -25.855 -4.340 -86.812 1.00 49.75 ? 439 GLU C OE2 1 +ATOM 5814 N N . THR B 2 440 ? -20.231 -6.662 -89.220 1.00 45.99 ? 440 THR C N 1 +ATOM 5815 C CA . THR B 2 440 ? -19.075 -6.465 -90.093 1.00 43.58 ? 440 THR C CA 1 +ATOM 5816 C C . THR B 2 440 ? -19.525 -5.890 -91.430 1.00 44.85 ? 440 THR C C 1 +ATOM 5817 O O . THR B 2 440 ? -20.485 -5.117 -91.480 1.00 53.53 ? 440 THR C O 1 +ATOM 5818 C CB . THR B 2 440 ? -18.315 -7.767 -90.324 1.00 46.85 ? 440 THR C CB 1 +ATOM 5819 O OG1 . THR B 2 440 ? -18.531 -8.649 -89.223 1.00 52.18 ? 440 THR C OG1 1 +ATOM 5820 C CG2 . THR B 2 440 ? -16.831 -7.484 -90.437 1.00 49.08 ? 440 THR C CG2 1 +ATOM 5821 N N . PHE B 2 441 ? -18.882 -6.282 -92.530 1.00 42.18 ? 441 PHE C N 1 +ATOM 5822 C CA . PHE B 2 441 ? -19.248 -5.684 -93.806 1.00 46.42 ? 441 PHE C CA 1 +ATOM 5823 C C . PHE B 2 441 ? -19.279 -6.683 -94.957 1.00 54.46 ? 441 PHE C C 1 +ATOM 5824 O O . PHE B 2 441 ? -19.407 -6.258 -96.113 1.00 64.93 ? 441 PHE C O 1 +ATOM 5825 C CB . PHE B 2 441 ? -18.314 -4.506 -94.145 1.00 50.16 ? 441 PHE C CB 1 +ATOM 5826 C CG . PHE B 2 441 ? -18.829 -3.153 -93.673 1.00 46.93 ? 441 PHE C CG 1 +ATOM 5827 C CD1 . PHE B 2 441 ? -19.821 -2.479 -94.372 1.00 41.46 ? 441 PHE C CD1 1 +ATOM 5828 C CD2 . PHE B 2 441 ? -18.318 -2.561 -92.528 1.00 43.86 ? 441 PHE C CD2 1 +ATOM 5829 C CE1 . PHE B 2 441 ? -20.284 -1.247 -93.935 1.00 38.00 ? 441 PHE C CE1 1 +ATOM 5830 C CE2 . PHE B 2 441 ? -18.782 -1.331 -92.093 1.00 38.00 ? 441 PHE C CE2 1 +ATOM 5831 C CZ . PHE B 2 441 ? -19.763 -0.676 -92.796 1.00 38.00 ? 441 PHE C CZ 1 +ATOM 5832 N N . GLU B 2 442 ? -19.153 -7.984 -94.692 1.00 54.63 ? 442 GLU C N 1 +ATOM 5833 C CA . GLU B 2 442 ? -19.471 -9.011 -95.683 1.00 59.31 ? 442 GLU C CA 1 +ATOM 5834 C C . GLU B 2 442 ? -18.625 -8.896 -96.947 1.00 59.95 ? 442 GLU C C 1 +ATOM 5835 O O . GLU B 2 442 ? -17.819 -9.785 -97.246 1.00 62.61 ? 442 GLU C O 1 +ATOM 5836 C CB . GLU B 2 442 ? -20.961 -8.942 -96.047 1.00 60.71 ? 442 GLU C CB 1 +ATOM 5837 C CG . GLU B 2 442 ? -21.817 -10.118 -95.578 1.00 61.35 ? 442 GLU C CG 1 +ATOM 5838 C CD . GLU B 2 442 ? -21.654 -11.365 -96.434 1.00 79.49 ? 442 GLU C CD 1 +ATOM 5839 O OE1 . GLU B 2 442 ? -21.736 -12.483 -95.882 1.00 76.49 ? 442 GLU C OE1 1 +ATOM 5840 O OE2 . GLU B 2 442 ? -21.446 -11.226 -97.661 1.00 84.37 ? 442 GLU C OE2 1 +ATOM 5841 N N . LYS B 2 443 ? -18.790 -7.800 -97.692 1.00 56.42 ? 443 LYS C N 1 +ATOM 5842 C CA . LYS B 2 443 ? -18.082 -7.629 -98.955 1.00 62.35 ? 443 LYS C CA 1 +ATOM 5843 C C . LYS B 2 443 ? -16.569 -7.601 -98.779 1.00 68.14 ? 443 LYS C C 1 +ATOM 5844 O O . LYS B 2 443 ? -15.843 -7.717 -99.771 1.00 80.59 ? 443 LYS C O 1 +ATOM 5845 C CB . LYS B 2 443 ? -18.558 -6.333 -99.636 1.00 73.74 ? 443 LYS C CB 1 +ATOM 5846 C CG . LYS B 2 443 ? -18.213 -6.210 -101.125 1.00 101.07 ? 443 LYS C CG 1 +ATOM 5847 C CD . LYS B 2 443 ? -18.810 -4.945 -101.738 1.00 103.04 ? 443 LYS C CD 1 +ATOM 5848 C CE . LYS B 2 443 ? -18.482 -4.828 -103.224 1.00 107.22 ? 443 LYS C CE 1 +ATOM 5849 N NZ . LYS B 2 443 ? -19.031 -3.577 -103.826 1.00 99.10 ? 443 LYS C NZ 1 +ATOM 5850 N N . PHE B 2 444 ? -16.077 -7.533 -97.546 1.00 65.39 ? 444 PHE C N 1 +ATOM 5851 C CA . PHE B 2 444 ? -14.649 -7.476 -97.266 1.00 59.65 ? 444 PHE C CA 1 +ATOM 5852 C C . PHE B 2 444 ? -14.058 -8.828 -96.932 1.00 57.70 ? 444 PHE C C 1 +ATOM 5853 O O . PHE B 2 444 ? -12.933 -9.124 -97.340 1.00 60.50 ? 444 PHE C O 1 +ATOM 5854 C CB . PHE B 2 444 ? -14.379 -6.530 -96.101 1.00 58.85 ? 444 PHE C CB 1 +ATOM 5855 C CG . PHE B 2 444 ? -14.485 -5.083 -96.455 1.00 59.68 ? 444 PHE C CG 1 +ATOM 5856 C CD1 . PHE B 2 444 ? -14.099 -4.636 -97.705 1.00 64.18 ? 444 PHE C CD1 1 +ATOM 5857 C CD2 . PHE B 2 444 ? -14.985 -4.171 -95.542 1.00 52.42 ? 444 PHE C CD2 1 +ATOM 5858 C CE1 . PHE B 2 444 ? -14.199 -3.306 -98.032 1.00 64.65 ? 444 PHE C CE1 1 +ATOM 5859 C CE2 . PHE B 2 444 ? -15.085 -2.845 -95.860 1.00 51.55 ? 444 PHE C CE2 1 +ATOM 5860 C CZ . PHE B 2 444 ? -14.694 -2.409 -97.108 1.00 67.12 ? 444 PHE C CZ 1 +ATOM 5861 N N . GLY B 2 445 ? -14.791 -9.641 -96.192 1.00 57.76 ? 445 GLY C N 1 +ATOM 5862 C CA . GLY B 2 445 ? -14.321 -10.909 -95.694 1.00 58.11 ? 445 GLY C CA 1 +ATOM 5863 C C . GLY B 2 445 ? -14.062 -10.866 -94.203 1.00 54.82 ? 445 GLY C C 1 +ATOM 5864 O O . GLY B 2 445 ? -14.469 -9.943 -93.493 1.00 56.15 ? 445 GLY C O 1 +ATOM 5865 N N . ASN B 2 446 ? -13.324 -11.867 -93.732 1.00 59.59 ? 446 ASN C N 1 +ATOM 5866 C CA . ASN B 2 446 ? -13.062 -12.018 -92.309 1.00 61.76 ? 446 ASN C CA 1 +ATOM 5867 C C . ASN B 2 446 ? -11.867 -11.189 -91.852 1.00 67.68 ? 446 ASN C C 1 +ATOM 5868 O O . ASN B 2 446 ? -11.317 -11.447 -90.775 1.00 71.35 ? 446 ASN C O 1 +ATOM 5869 C CB . ASN B 2 446 ? -12.839 -13.499 -91.963 1.00 61.55 ? 446 ASN C CB 1 +ATOM 5870 C CG . ASN B 2 446 ? -14.122 -14.330 -92.016 1.00 54.37 ? 446 ASN C CG 1 +ATOM 5871 O OD1 . ASN B 2 446 ? -15.185 -13.869 -91.613 1.00 52.93 ? 446 ASN C OD1 1 +ATOM 5872 N ND2 . ASN B 2 446 ? -14.012 -15.575 -92.481 1.00 48.37 ? 446 ASN C ND2 1 +ATOM 5873 N N . ASP B 2 447 ? -11.492 -10.167 -92.619 1.00 68.87 ? 447 ASP C N 1 +ATOM 5874 C CA . ASP B 2 447 ? -10.274 -9.399 -92.395 1.00 69.52 ? 447 ASP C CA 1 +ATOM 5875 C C . ASP B 2 447 ? -10.574 -7.916 -92.217 1.00 69.72 ? 447 ASP C C 1 +ATOM 5876 O O . ASP B 2 447 ? -9.895 -7.060 -92.789 1.00 72.95 ? 447 ASP C O 1 +ATOM 5877 C CB . ASP B 2 447 ? -9.296 -9.582 -93.554 1.00 69.27 ? 447 ASP C CB 1 +ATOM 5878 C CG . ASP B 2 447 ? -8.970 -11.034 -93.825 1.00 74.61 ? 447 ASP C CG 1 +ATOM 5879 O OD1 . ASP B 2 447 ? -8.843 -11.820 -92.860 1.00 74.38 ? 447 ASP C OD1 1 +ATOM 5880 O OD2 . ASP B 2 447 ? -8.876 -11.392 -95.016 1.00 74.00 ? 447 ASP C OD2 1 +ATOM 5881 N N . THR B 2 448 ? -11.598 -7.586 -91.431 1.00 66.96 ? 448 THR C N 1 +ATOM 5882 C CA . THR B 2 448 ? -11.964 -6.195 -91.205 1.00 58.39 ? 448 THR C CA 1 +ATOM 5883 C C . THR B 2 448 ? -12.283 -5.970 -89.740 1.00 59.69 ? 448 THR C C 1 +ATOM 5884 O O . THR B 2 448 ? -12.267 -6.892 -88.919 1.00 65.27 ? 448 THR C O 1 +ATOM 5885 C CB . THR B 2 448 ? -13.161 -5.755 -92.044 1.00 51.07 ? 448 THR C CB 1 +ATOM 5886 O OG1 . THR B 2 448 ? -14.119 -6.816 -92.121 1.00 57.58 ? 448 THR C OG1 1 +ATOM 5887 C CG2 . THR B 2 448 ? -12.699 -5.381 -93.409 1.00 60.72 ? 448 THR C CG2 1 +ATOM 5888 N N . PHE B 2 449 ? -12.576 -4.714 -89.431 1.00 54.84 ? 449 PHE C N 1 +ATOM 5889 C CA . PHE B 2 449 ? -12.913 -4.282 -88.091 1.00 53.72 ? 449 PHE C CA 1 +ATOM 5890 C C . PHE B 2 449 ? -14.347 -4.661 -87.755 1.00 52.07 ? 449 PHE C C 1 +ATOM 5891 O O . PHE B 2 449 ? -15.091 -5.213 -88.572 1.00 49.75 ? 449 PHE C O 1 +ATOM 5892 C CB . PHE B 2 449 ? -12.735 -2.777 -87.961 1.00 59.14 ? 449 PHE C CB 1 +ATOM 5893 C CG . PHE B 2 449 ? -13.769 -1.983 -88.711 1.00 53.62 ? 449 PHE C CG 1 +ATOM 5894 C CD1 . PHE B 2 449 ? -13.701 -1.865 -90.087 1.00 48.40 ? 449 PHE C CD1 1 +ATOM 5895 C CD2 . PHE B 2 449 ? -14.808 -1.359 -88.040 1.00 56.39 ? 449 PHE C CD2 1 +ATOM 5896 C CE1 . PHE B 2 449 ? -14.639 -1.136 -90.779 1.00 46.01 ? 449 PHE C CE1 1 +ATOM 5897 C CE2 . PHE B 2 449 ? -15.752 -0.630 -88.730 1.00 50.13 ? 449 PHE C CE2 1 +ATOM 5898 C CZ . PHE B 2 449 ? -15.666 -0.519 -90.102 1.00 43.64 ? 449 PHE C CZ 1 +ATOM 5899 N N . ILE B 2 450 ? -14.745 -4.323 -86.537 1.00 48.57 ? 450 ILE C N 1 +ATOM 5900 C CA . ILE B 2 450 ? -16.088 -4.577 -86.048 1.00 46.73 ? 450 ILE C CA 1 +ATOM 5901 C C . ILE B 2 450 ? -16.744 -3.232 -85.764 1.00 40.15 ? 450 ILE C C 1 +ATOM 5902 O O . ILE B 2 450 ? -16.137 -2.359 -85.135 1.00 38.00 ? 450 ILE C O 1 +ATOM 5903 C CB . ILE B 2 450 ? -16.066 -5.489 -84.808 1.00 43.94 ? 450 ILE C CB 1 +ATOM 5904 C CG1 . ILE B 2 450 ? -15.129 -4.947 -83.737 1.00 53.37 ? 450 ILE C CG1 1 +ATOM 5905 C CG2 . ILE B 2 450 ? -15.547 -6.856 -85.183 1.00 42.73 ? 450 ILE C CG2 1 +ATOM 5906 C CD1 . ILE B 2 450 ? -14.913 -5.928 -82.612 1.00 58.00 ? 450 ILE C CD1 1 +ATOM 5907 N N . ILE B 2 451 ? -17.937 -3.032 -86.314 1.00 38.30 ? 451 ILE C N 1 +ATOM 5908 C CA . ILE B 2 451 ? -18.683 -1.796 -86.100 1.00 38.00 ? 451 ILE C CA 1 +ATOM 5909 C C . ILE B 2 451 ? -19.290 -1.834 -84.705 1.00 38.00 ? 451 ILE C C 1 +ATOM 5910 O O . ILE B 2 451 ? -20.108 -2.706 -84.392 1.00 38.00 ? 451 ILE C O 1 +ATOM 5911 C CB . ILE B 2 451 ? -19.773 -1.597 -87.165 1.00 38.00 ? 451 ILE C CB 1 +ATOM 5912 C CG1 . ILE B 2 451 ? -19.208 -1.712 -88.576 1.00 38.00 ? 451 ILE C CG1 1 +ATOM 5913 C CG2 . ILE B 2 451 ? -20.445 -0.254 -87.004 1.00 44.95 ? 451 ILE C CG2 1 +ATOM 5914 C CD1 . ILE B 2 451 ? -19.407 -3.052 -89.179 1.00 38.00 ? 451 ILE C CD1 1 +ATOM 5915 N N . HIS B 2 452 ? -18.914 -0.870 -83.877 1.00 38.00 ? 452 HIS C N 1 +ATOM 5916 C CA . HIS B 2 452 ? -19.402 -0.776 -82.508 1.00 38.04 ? 452 HIS C CA 1 +ATOM 5917 C C . HIS B 2 452 ? -20.717 0.006 -82.537 1.00 39.16 ? 452 HIS C C 1 +ATOM 5918 O O . HIS B 2 452 ? -20.719 1.239 -82.530 1.00 38.95 ? 452 HIS C O 1 +ATOM 5919 C CB . HIS B 2 452 ? -18.351 -0.116 -81.622 1.00 40.91 ? 452 HIS C CB 1 +ATOM 5920 C CG . HIS B 2 452 ? -17.014 -0.808 -81.619 1.00 39.65 ? 452 HIS C CG 1 +ATOM 5921 N ND1 . HIS B 2 452 ? -15.851 -0.173 -81.234 1.00 43.03 ? 452 HIS C ND1 1 +ATOM 5922 C CD2 . HIS B 2 452 ? -16.657 -2.076 -81.931 1.00 39.52 ? 452 HIS C CD2 1 +ATOM 5923 C CE1 . HIS B 2 452 ? -14.837 -1.016 -81.317 1.00 40.34 ? 452 HIS C CE1 1 +ATOM 5924 N NE2 . HIS B 2 452 ? -15.300 -2.179 -81.736 1.00 38.00 ? 452 HIS C NE2 1 +ATOM 5925 N N . LEU B 2 453 ? -21.835 -0.711 -82.588 1.00 41.81 ? 453 LEU C N 1 +ATOM 5926 C CA . LEU B 2 453 ? -23.176 -0.139 -82.661 1.00 38.91 ? 453 LEU C CA 1 +ATOM 5927 C C . LEU B 2 453 ? -23.931 -0.397 -81.364 1.00 44.04 ? 453 LEU C C 1 +ATOM 5928 O O . LEU B 2 453 ? -23.561 -1.262 -80.569 1.00 52.08 ? 453 LEU C O 1 +ATOM 5929 C CB . LEU B 2 453 ? -23.963 -0.745 -83.821 1.00 42.79 ? 453 LEU C CB 1 +ATOM 5930 C CG . LEU B 2 453 ? -23.453 -0.449 -85.218 1.00 38.00 ? 453 LEU C CG 1 +ATOM 5931 C CD1 . LEU B 2 453 ? -24.242 -1.251 -86.224 1.00 38.00 ? 453 LEU C CD1 1 +ATOM 5932 C CD2 . LEU B 2 453 ? -23.579 1.024 -85.483 1.00 46.03 ? 453 LEU C CD2 1 +ATOM 5933 N N . ASP B 2 454 ? -25.029 0.338 -81.184 1.00 46.82 ? 454 ASP C N 1 +ATOM 5934 C CA . ASP B 2 454 ? -25.901 0.224 -80.008 1.00 63.10 ? 454 ASP C CA 1 +ATOM 5935 C C . ASP B 2 454 ? -25.110 0.350 -78.701 1.00 59.49 ? 454 ASP C C 1 +ATOM 5936 O O . ASP B 2 454 ? -25.120 -0.535 -77.841 1.00 62.37 ? 454 ASP C O 1 +ATOM 5937 C CB . ASP B 2 454 ? -26.691 -1.091 -80.042 1.00 74.63 ? 454 ASP C CB 1 +ATOM 5938 C CG . ASP B 2 454 ? -27.769 -1.102 -81.114 1.00 71.48 ? 454 ASP C CG 1 +ATOM 5939 O OD1 . ASP B 2 454 ? -27.404 -1.222 -82.300 1.00 67.62 ? 454 ASP C OD1 1 +ATOM 5940 O OD2 . ASP B 2 454 ? -28.975 -1.026 -80.772 1.00 73.32 ? 454 ASP C OD2 1 +ATOM 5941 N N . ASN B 2 455 ? -24.460 1.498 -78.539 1.00 46.95 ? 455 ASN C N 1 +ATOM 5942 C CA . ASN B 2 455 ? -23.635 1.753 -77.368 1.00 44.80 ? 455 ASN C CA 1 +ATOM 5943 C C . ASN B 2 455 ? -24.414 2.400 -76.249 1.00 50.74 ? 455 ASN C C 1 +ATOM 5944 O O . ASN B 2 455 ? -23.814 2.822 -75.256 1.00 51.23 ? 455 ASN C O 1 +ATOM 5945 C CB . ASN B 2 455 ? -22.462 2.654 -77.729 1.00 42.33 ? 455 ASN C CB 1 +ATOM 5946 C CG . ASN B 2 455 ? -21.772 2.210 -78.965 1.00 44.24 ? 455 ASN C CG 1 +ATOM 5947 O OD1 . ASN B 2 455 ? -21.510 1.025 -79.134 1.00 48.20 ? 455 ASN C OD1 1 +ATOM 5948 N ND2 . ASN B 2 455 ? -21.482 3.148 -79.858 1.00 44.74 ? 455 ASN C ND2 1 +ATOM 5949 N N . GLY B 2 456 ? -25.736 2.461 -76.372 1.00 52.71 ? 456 GLY C N 1 +ATOM 5950 C CA . GLY B 2 456 ? -26.522 3.233 -75.439 1.00 54.56 ? 456 GLY C CA 1 +ATOM 5951 C C . GLY B 2 456 ? -26.585 2.658 -74.047 1.00 52.40 ? 456 GLY C C 1 +ATOM 5952 O O . GLY B 2 456 ? -27.086 3.336 -73.145 1.00 57.80 ? 456 GLY C O 1 +ATOM 5953 N N . ARG B 2 457 ? -26.080 1.446 -73.842 1.00 49.53 ? 457 ARG C N 1 +ATOM 5954 C CA . ARG B 2 457 ? -26.161 0.794 -72.545 1.00 52.19 ? 457 ARG C CA 1 +ATOM 5955 C C . ARG B 2 457 ? -24.952 1.072 -71.665 1.00 54.48 ? 457 ARG C C 1 +ATOM 5956 O O . ARG B 2 457 ? -24.898 0.579 -70.534 1.00 59.43 ? 457 ARG C O 1 +ATOM 5957 C CB . ARG B 2 457 ? -26.341 -0.711 -72.734 1.00 58.06 ? 457 ARG C CB 1 +ATOM 5958 C CG . ARG B 2 457 ? -27.488 -1.055 -73.663 1.00 57.14 ? 457 ARG C CG 1 +ATOM 5959 C CD . ARG B 2 457 ? -28.652 -1.682 -72.918 1.00 54.75 ? 457 ARG C CD 1 +ATOM 5960 N NE . ARG B 2 457 ? -29.777 -1.934 -73.813 1.00 50.53 ? 457 ARG C NE 1 +ATOM 5961 C CZ . ARG B 2 457 ? -30.875 -2.594 -73.465 1.00 52.37 ? 457 ARG C CZ 1 +ATOM 5962 N NH1 . ARG B 2 457 ? -31.002 -3.082 -72.241 1.00 53.04 ? 457 ARG C NH1 1 +ATOM 5963 N NH2 . ARG B 2 457 ? -31.848 -2.768 -74.343 1.00 58.54 ? 457 ARG C NH2 1 +ATOM 5964 N N . GLY B 2 458 ? -23.980 1.835 -72.153 1.00 49.48 ? 458 GLY C N 1 +ATOM 5965 C CA . GLY B 2 458 ? -22.854 2.213 -71.336 1.00 49.02 ? 458 GLY C CA 1 +ATOM 5966 C C . GLY B 2 458 ? -23.168 3.429 -70.487 1.00 56.34 ? 458 GLY C C 1 +ATOM 5967 O O . GLY B 2 458 ? -24.236 4.036 -70.579 1.00 50.47 ? 458 GLY C O 1 +ATOM 5968 N N . PHE B 2 459 ? -22.207 3.773 -69.631 1.00 61.75 ? 459 PHE C N 1 +ATOM 5969 C CA . PHE B 2 459 ? -22.279 4.959 -68.776 1.00 57.96 ? 459 PHE C CA 1 +ATOM 5970 C C . PHE B 2 459 ? -23.558 4.968 -67.939 1.00 60.78 ? 459 PHE C C 1 +ATOM 5971 O O . PHE B 2 459 ? -24.269 5.971 -67.846 1.00 59.78 ? 459 PHE C O 1 +ATOM 5972 C CB . PHE B 2 459 ? -22.158 6.238 -69.605 1.00 52.14 ? 459 PHE C CB 1 +ATOM 5973 C CG . PHE B 2 459 ? -20.879 6.334 -70.377 1.00 47.28 ? 459 PHE C CG 1 +ATOM 5974 C CD1 . PHE B 2 459 ? -19.739 6.848 -69.792 1.00 49.05 ? 459 PHE C CD1 1 +ATOM 5975 C CD2 . PHE B 2 459 ? -20.820 5.911 -71.692 1.00 47.86 ? 459 PHE C CD2 1 +ATOM 5976 C CE1 . PHE B 2 459 ? -18.555 6.935 -70.503 1.00 50.16 ? 459 PHE C CE1 1 +ATOM 5977 C CE2 . PHE B 2 459 ? -19.646 5.996 -72.410 1.00 52.78 ? 459 PHE C CE2 1 +ATOM 5978 C CZ . PHE B 2 459 ? -18.509 6.509 -71.816 1.00 51.94 ? 459 PHE C CZ 1 +ATOM 5979 N N . GLY B 2 460 ? -23.861 3.824 -67.335 1.00 62.11 ? 460 GLY C N 1 +ATOM 5980 C CA . GLY B 2 460 ? -25.029 3.733 -66.486 1.00 59.76 ? 460 GLY C CA 1 +ATOM 5981 C C . GLY B 2 460 ? -24.680 3.750 -65.016 1.00 61.98 ? 460 GLY C C 1 +ATOM 5982 O O . GLY B 2 460 ? -25.520 4.054 -64.165 1.00 63.15 ? 460 GLY C O 1 +ATOM 5983 N N . LYS B 2 461 ? -23.426 3.438 -64.705 1.00 56.81 ? 461 LYS C N 1 +ATOM 5984 C CA . LYS B 2 461 ? -22.964 3.361 -63.327 1.00 58.61 ? 461 LYS C CA 1 +ATOM 5985 C C . LYS B 2 461 ? -21.563 3.947 -63.275 1.00 59.80 ? 461 LYS C C 1 +ATOM 5986 O O . LYS B 2 461 ? -20.678 3.502 -64.012 1.00 54.16 ? 461 LYS C O 1 +ATOM 5987 C CB . LYS B 2 461 ? -22.982 1.912 -62.817 1.00 66.55 ? 461 LYS C CB 1 +ATOM 5988 C CG . LYS B 2 461 ? -24.366 1.249 -62.878 1.00 65.18 ? 461 LYS C CG 1 +ATOM 5989 C CD . LYS B 2 461 ? -24.325 -0.233 -62.526 1.00 62.33 ? 461 LYS C CD 1 +ATOM 5990 C CE . LYS B 2 461 ? -24.084 -0.447 -61.041 1.00 81.95 ? 461 LYS C CE 1 +ATOM 5991 N NZ . LYS B 2 461 ? -25.144 0.195 -60.211 1.00 80.31 ? 461 LYS C NZ 1 +ATOM 5992 N N . HIS B 2 462 ? -21.376 4.969 -62.440 1.00 64.70 ? 462 HIS C N 1 +ATOM 5993 C CA . HIS B 2 462 ? -20.079 5.617 -62.287 1.00 67.33 ? 462 HIS C CA 1 +ATOM 5994 C C . HIS B 2 462 ? -19.347 5.190 -61.024 1.00 73.43 ? 462 HIS C C 1 +ATOM 5995 O O . HIS B 2 462 ? -18.116 5.293 -60.977 1.00 70.39 ? 462 HIS C O 1 +ATOM 5996 C CB . HIS B 2 462 ? -20.244 7.142 -62.283 1.00 59.76 ? 462 HIS C CB 1 +ATOM 5997 C CG . HIS B 2 462 ? -21.065 7.649 -61.141 1.00 61.73 ? 462 HIS C CG 1 +ATOM 5998 N ND1 . HIS B 2 462 ? -20.549 7.838 -59.878 1.00 66.83 ? 462 HIS C ND1 1 +ATOM 5999 C CD2 . HIS B 2 462 ? -22.374 7.987 -61.068 1.00 64.80 ? 462 HIS C CD2 1 +ATOM 6000 C CE1 . HIS B 2 462 ? -21.503 8.281 -59.078 1.00 70.46 ? 462 HIS C CE1 1 +ATOM 6001 N NE2 . HIS B 2 462 ? -22.622 8.376 -59.775 1.00 63.41 ? 462 HIS C NE2 1 +ATOM 6002 N N . SER B 2 463 ? -20.069 4.714 -60.013 1.00 73.02 ? 463 SER C N 1 +ATOM 6003 C CA . SER B 2 463 ? -19.482 4.187 -58.791 1.00 74.26 ? 463 SER C CA 1 +ATOM 6004 C C . SER B 2 463 ? -19.245 2.683 -58.856 1.00 81.11 ? 463 SER C C 1 +ATOM 6005 O O . SER B 2 463 ? -19.003 2.057 -57.818 1.00 93.29 ? 463 SER C O 1 +ATOM 6006 C CB . SER B 2 463 ? -20.382 4.523 -57.598 1.00 77.03 ? 463 SER C CB 1 +ATOM 6007 O OG . SER B 2 463 ? -21.654 3.905 -57.730 1.00 76.03 ? 463 SER C OG 1 +ATOM 6008 N N . HIS B 2 464 ? -19.300 2.092 -60.046 1.00 76.33 ? 464 HIS C N 1 +ATOM 6009 C CA . HIS B 2 464 ? -19.204 0.649 -60.200 1.00 76.78 ? 464 HIS C CA 1 +ATOM 6010 C C . HIS B 2 464 ? -18.414 0.326 -61.457 1.00 69.77 ? 464 HIS C C 1 +ATOM 6011 O O . HIS B 2 464 ? -18.562 0.995 -62.483 1.00 69.79 ? 464 HIS C O 1 +ATOM 6012 C CB . HIS B 2 464 ? -20.597 0.007 -60.267 1.00 70.53 ? 464 HIS C CB 1 +ATOM 6013 C CG . HIS B 2 464 ? -20.584 -1.488 -60.177 1.00 74.02 ? 464 HIS C CG 1 +ATOM 6014 N ND1 . HIS B 2 464 ? -19.912 -2.285 -61.079 1.00 73.08 ? 464 HIS C ND1 1 +ATOM 6015 C CD2 . HIS B 2 464 ? -21.166 -2.332 -59.293 1.00 79.13 ? 464 HIS C CD2 1 +ATOM 6016 C CE1 . HIS B 2 464 ? -20.077 -3.554 -60.754 1.00 73.04 ? 464 HIS C CE1 1 +ATOM 6017 N NE2 . HIS B 2 464 ? -20.835 -3.610 -59.674 1.00 82.92 ? 464 HIS C NE2 1 +ATOM 6018 N N . ASP B 2 465 ? -17.566 -0.691 -61.365 1.00 64.36 ? 465 ASP C N 1 +ATOM 6019 C CA . ASP B 2 465 ? -16.805 -1.187 -62.507 1.00 64.59 ? 465 ASP C CA 1 +ATOM 6020 C C . ASP B 2 465 ? -17.205 -2.641 -62.727 1.00 65.49 ? 465 ASP C C 1 +ATOM 6021 O O . ASP B 2 465 ? -16.792 -3.530 -61.976 1.00 64.43 ? 465 ASP C O 1 +ATOM 6022 C CB . ASP B 2 465 ? -15.307 -1.043 -62.278 1.00 66.08 ? 465 ASP C CB 1 +ATOM 6023 C CG . ASP B 2 465 ? -14.909 0.374 -61.955 1.00 67.26 ? 465 ASP C CG 1 +ATOM 6024 O OD1 . ASP B 2 465 ? -15.608 1.297 -62.419 1.00 71.65 ? 465 ASP C OD1 1 +ATOM 6025 O OD2 . ASP B 2 465 ? -13.906 0.565 -61.235 1.00 66.83 ? 465 ASP C OD2 1 +ATOM 6026 N N . GLU B 2 466 ? -18.025 -2.875 -63.743 1.00 68.10 ? 466 GLU C N 1 +ATOM 6027 C CA . GLU B 2 466 ? -18.492 -4.220 -64.055 1.00 64.88 ? 466 GLU C CA 1 +ATOM 6028 C C . GLU B 2 466 ? -17.337 -5.005 -64.656 1.00 59.26 ? 466 GLU C C 1 +ATOM 6029 O O . GLU B 2 466 ? -16.997 -4.838 -65.829 1.00 57.42 ? 466 GLU C O 1 +ATOM 6030 C CB . GLU B 2 466 ? -19.683 -4.165 -65.003 1.00 69.82 ? 466 GLU C CB 1 +ATOM 6031 C CG . GLU B 2 466 ? -20.218 -5.527 -65.371 1.00 67.20 ? 466 GLU C CG 1 +ATOM 6032 C CD . GLU B 2 466 ? -20.812 -6.250 -64.183 1.00 69.86 ? 466 GLU C CD 1 +ATOM 6033 O OE1 . GLU B 2 466 ? -21.098 -5.590 -63.161 1.00 67.08 ? 466 GLU C OE1 1 +ATOM 6034 O OE2 . GLU B 2 466 ? -20.994 -7.481 -64.272 1.00 78.82 ? 466 GLU C OE2 1 +ATOM 6035 N N . MET B 2 467 ? -16.721 -5.862 -63.843 1.00 58.88 ? 467 MET C N 1 +ATOM 6036 C CA . MET B 2 467 ? -15.556 -6.622 -64.274 1.00 63.32 ? 467 MET C CA 1 +ATOM 6037 C C . MET B 2 467 ? -15.898 -7.733 -65.260 1.00 61.09 ? 467 MET C C 1 +ATOM 6038 O O . MET B 2 467 ? -14.995 -8.236 -65.941 1.00 52.84 ? 467 MET C O 1 +ATOM 6039 C CB . MET B 2 467 ? -14.856 -7.204 -63.047 1.00 62.08 ? 467 MET C CB 1 +ATOM 6040 C CG . MET B 2 467 ? -14.407 -6.146 -62.065 1.00 50.85 ? 467 MET C CG 1 +ATOM 6041 S SD . MET B 2 467 ? -13.290 -4.967 -62.843 1.00 61.91 ? 467 MET C SD 1 +ATOM 6042 C CE . MET B 2 467 ? -11.947 -6.045 -63.352 1.00 63.81 ? 467 MET C CE 1 +ATOM 6043 N N . SER B 2 468 ? -17.176 -8.099 -65.376 1.00 58.27 ? 468 SER C N 1 +ATOM 6044 C CA . SER B 2 468 ? -17.562 -9.184 -66.269 1.00 55.53 ? 468 SER C CA 1 +ATOM 6045 C C . SER B 2 468 ? -17.234 -8.861 -67.718 1.00 53.34 ? 468 SER C C 1 +ATOM 6046 O O . SER B 2 468 ? -16.980 -9.770 -68.516 1.00 56.87 ? 468 SER C O 1 +ATOM 6047 C CB . SER B 2 468 ? -19.056 -9.473 -66.116 1.00 55.76 ? 468 SER C CB 1 +ATOM 6048 O OG . SER B 2 468 ? -19.374 -9.789 -64.772 1.00 60.87 ? 468 SER C OG 1 +ATOM 6049 N N . ILE B 2 469 ? -17.207 -7.578 -68.072 1.00 49.60 ? 469 ILE C N 1 +ATOM 6050 C CA . ILE B 2 469 ? -16.889 -7.213 -69.443 1.00 49.15 ? 469 ILE C CA 1 +ATOM 6051 C C . ILE B 2 469 ? -15.447 -7.565 -69.763 1.00 50.27 ? 469 ILE C C 1 +ATOM 6052 O O . ILE B 2 469 ? -15.125 -7.930 -70.899 1.00 53.15 ? 469 ILE C O 1 +ATOM 6053 C CB . ILE B 2 469 ? -17.158 -5.716 -69.664 1.00 50.19 ? 469 ILE C CB 1 +ATOM 6054 C CG1 . ILE B 2 469 ? -18.588 -5.371 -69.259 1.00 50.71 ? 469 ILE C CG1 1 +ATOM 6055 C CG2 . ILE B 2 469 ? -16.897 -5.334 -71.109 1.00 52.61 ? 469 ILE C CG2 1 +ATOM 6056 C CD1 . ILE B 2 469 ? -18.880 -3.897 -69.315 1.00 53.54 ? 469 ILE C CD1 1 +ATOM 6057 N N . LEU B 2 470 ? -14.560 -7.478 -68.774 1.00 48.73 ? 470 LEU C N 1 +ATOM 6058 C CA . LEU B 2 470 ? -13.148 -7.737 -69.013 1.00 51.15 ? 470 LEU C CA 1 +ATOM 6059 C C . LEU B 2 470 ? -12.839 -9.215 -69.215 1.00 53.27 ? 470 LEU C C 1 +ATOM 6060 O O . LEU B 2 470 ? -11.750 -9.536 -69.700 1.00 53.00 ? 470 LEU C O 1 +ATOM 6061 C CB . LEU B 2 470 ? -12.319 -7.181 -67.853 1.00 51.97 ? 470 LEU C CB 1 +ATOM 6062 C CG . LEU B 2 470 ? -11.149 -6.266 -68.229 1.00 53.44 ? 470 LEU C CG 1 +ATOM 6063 C CD1 . LEU B 2 470 ? -9.944 -7.058 -68.701 1.00 47.40 ? 470 LEU C CD1 1 +ATOM 6064 C CD2 . LEU B 2 470 ? -11.574 -5.278 -69.294 1.00 52.35 ? 470 LEU C CD2 1 +ATOM 6065 N N . VAL B 2 471 ? -13.780 -10.108 -68.883 1.00 52.09 ? 471 VAL C N 1 +ATOM 6066 C CA . VAL B 2 471 ? -13.475 -11.544 -68.905 1.00 46.19 ? 471 VAL C CA 1 +ATOM 6067 C C . VAL B 2 471 ? -12.948 -12.007 -70.251 1.00 45.20 ? 471 VAL C C 1 +ATOM 6068 O O . VAL B 2 471 ? -12.012 -12.820 -70.274 1.00 43.72 ? 471 VAL C O 1 +ATOM 6069 C CB . VAL B 2 471 ? -14.703 -12.342 -68.429 1.00 47.21 ? 471 VAL C CB 1 +ATOM 6070 C CG1 . VAL B 2 471 ? -14.426 -13.826 -68.473 1.00 51.09 ? 471 VAL C CG1 1 +ATOM 6071 C CG2 . VAL B 2 471 ? -15.092 -11.911 -67.026 1.00 46.16 ? 471 VAL C CG2 1 +ATOM 6072 N N . PRO B 2 472 ? -13.462 -11.543 -71.400 1.00 46.97 ? 472 PRO C N 1 +ATOM 6073 C CA . PRO B 2 472 ? -12.795 -11.845 -72.681 1.00 46.70 ? 472 PRO C CA 1 +ATOM 6074 C C . PRO B 2 472 ? -11.297 -11.587 -72.687 1.00 48.52 ? 472 PRO C C 1 +ATOM 6075 O O . PRO B 2 472 ? -10.553 -12.313 -73.359 1.00 47.06 ? 472 PRO C O 1 +ATOM 6076 C CB . PRO B 2 472 ? -13.518 -10.923 -73.671 1.00 48.92 ? 472 PRO C CB 1 +ATOM 6077 C CG . PRO B 2 472 ? -14.841 -10.596 -73.027 1.00 53.54 ? 472 PRO C CG 1 +ATOM 6078 C CD . PRO B 2 472 ? -14.846 -11.083 -71.610 1.00 46.90 ? 472 PRO C CD 1 +ATOM 6079 N N . LEU B 2 473 ? -10.838 -10.547 -71.988 1.00 50.99 ? 473 LEU C N 1 +ATOM 6080 C CA . LEU B 2 473 ? -9.415 -10.223 -71.978 1.00 48.76 ? 473 LEU C CA 1 +ATOM 6081 C C . LEU B 2 473 ? -8.647 -11.068 -70.968 1.00 55.72 ? 473 LEU C C 1 +ATOM 6082 O O . LEU B 2 473 ? -7.532 -11.520 -71.256 1.00 57.88 ? 473 LEU C O 1 +ATOM 6083 C CB . LEU B 2 473 ? -9.224 -8.740 -71.672 1.00 40.66 ? 473 LEU C CB 1 +ATOM 6084 C CG . LEU B 2 473 ? -7.785 -8.236 -71.684 1.00 38.00 ? 473 LEU C CG 1 +ATOM 6085 C CD1 . LEU B 2 473 ? -7.125 -8.610 -72.993 1.00 43.05 ? 473 LEU C CD1 1 +ATOM 6086 C CD2 . LEU B 2 473 ? -7.747 -6.736 -71.472 1.00 45.86 ? 473 LEU C CD2 1 +ATOM 6087 N N . THR B 2 474 ? -9.229 -11.307 -69.789 1.00 54.47 ? 474 THR C N 1 +ATOM 6088 C CA . THR B 2 474 ? -8.549 -12.104 -68.775 1.00 52.34 ? 474 THR C CA 1 +ATOM 6089 C C . THR B 2 474 ? -8.447 -13.574 -69.155 1.00 54.69 ? 474 THR C C 1 +ATOM 6090 O O . THR B 2 474 ? -7.572 -14.271 -68.634 1.00 60.73 ? 474 THR C O 1 +ATOM 6091 C CB . THR B 2 474 ? -9.260 -11.969 -67.429 1.00 47.79 ? 474 THR C CB 1 +ATOM 6092 O OG1 . THR B 2 474 ? -10.600 -12.460 -67.548 1.00 51.05 ? 474 THR C OG1 1 +ATOM 6093 C CG2 . THR B 2 474 ? -9.285 -10.522 -66.977 1.00 49.45 ? 474 THR C CG2 1 +ATOM 6094 N N . GLN B 2 475 ? -9.299 -14.056 -70.059 1.00 52.61 ? 475 GLN C N 1 +ATOM 6095 C CA . GLN B 2 475 ? -9.227 -15.445 -70.493 1.00 53.56 ? 475 GLN C CA 1 +ATOM 6096 C C . GLN B 2 475 ? -8.405 -15.615 -71.756 1.00 57.38 ? 475 GLN C C 1 +ATOM 6097 O O . GLN B 2 475 ? -7.828 -16.688 -71.968 1.00 62.63 ? 475 GLN C O 1 +ATOM 6098 C CB . GLN B 2 475 ? -10.634 -16.011 -70.718 1.00 51.29 ? 475 GLN C CB 1 +ATOM 6099 C CG . GLN B 2 475 ? -11.457 -16.116 -69.445 1.00 53.66 ? 475 GLN C CG 1 +ATOM 6100 C CD . GLN B 2 475 ? -12.870 -16.628 -69.678 1.00 54.25 ? 475 GLN C CD 1 +ATOM 6101 O OE1 . GLN B 2 475 ? -13.380 -16.616 -70.800 1.00 51.34 ? 475 GLN C OE1 1 +ATOM 6102 N NE2 . GLN B 2 475 ? -13.518 -17.066 -68.605 1.00 58.42 ? 475 GLN C NE2 1 +ATOM 6103 N N . CYS B 2 476 ? -8.350 -14.588 -72.602 1.00 54.77 ? 476 CYS C N 1 +ATOM 6104 C CA . CYS B 2 476 ? -7.587 -14.646 -73.842 1.00 58.31 ? 476 CYS C CA 1 +ATOM 6105 C C . CYS B 2 476 ? -6.169 -14.129 -73.686 1.00 61.05 ? 476 CYS C C 1 +ATOM 6106 O O . CYS B 2 476 ? -5.233 -14.709 -74.247 1.00 60.29 ? 476 CYS C O 1 +ATOM 6107 C CB . CYS B 2 476 ? -8.299 -13.849 -74.930 1.00 56.49 ? 476 CYS C CB 1 +ATOM 6108 S SG . CYS B 2 476 ? -9.631 -14.773 -75.672 1.00 81.38 ? 476 CYS C SG 1 +ATOM 6109 N N . CYS B 2 477 ? -6.016 -13.019 -72.974 1.00 58.55 ? 477 CYS C N 1 +ATOM 6110 C CA . CYS B 2 477 ? -4.717 -12.458 -72.628 1.00 66.27 ? 477 CYS C CA 1 +ATOM 6111 C C . CYS B 2 477 ? -3.837 -12.260 -73.862 1.00 62.82 ? 477 CYS C C 1 +ATOM 6112 O O . CYS B 2 477 ? -2.783 -12.877 -74.029 1.00 59.88 ? 477 CYS C O 1 +ATOM 6113 C CB . CYS B 2 477 ? -4.033 -13.313 -71.571 1.00 69.08 ? 477 CYS C CB 1 +ATOM 6114 S SG . CYS B 2 477 ? -4.540 -12.813 -69.927 1.00 83.35 ? 477 CYS C SG 1 +ATOM 6115 N N . ARG B 2 478 ? -4.312 -11.377 -74.733 1.00 60.84 ? 478 ARG C N 1 +ATOM 6116 C CA . ARG B 2 478 ? -3.547 -10.904 -75.873 1.00 62.17 ? 478 ARG C CA 1 +ATOM 6117 C C . ARG B 2 478 ? -4.228 -9.656 -76.408 1.00 60.59 ? 478 ARG C C 1 +ATOM 6118 O O . ARG B 2 478 ? -5.457 -9.557 -76.383 1.00 53.22 ? 478 ARG C O 1 +ATOM 6119 C CB . ARG B 2 478 ? -3.418 -11.965 -76.968 1.00 57.92 ? 478 ARG C CB 1 +ATOM 6120 C CG . ARG B 2 478 ? -4.730 -12.496 -77.469 1.00 62.07 ? 478 ARG C CG 1 +ATOM 6121 C CD . ARG B 2 478 ? -4.545 -13.376 -78.693 1.00 67.00 ? 478 ARG C CD 1 +ATOM 6122 N NE . ARG B 2 478 ? -3.245 -14.037 -78.741 1.00 69.50 ? 478 ARG C NE 1 +ATOM 6123 C CZ . ARG B 2 478 ? -2.260 -13.684 -79.559 1.00 66.81 ? 478 ARG C CZ 1 +ATOM 6124 N NH1 . ARG B 2 478 ? -2.429 -12.670 -80.393 1.00 62.39 ? 478 ARG C NH1 1 +ATOM 6125 N NH2 . ARG B 2 478 ? -1.110 -14.344 -79.546 1.00 68.61 ? 478 ARG C NH2 1 +ATOM 6126 N N . VAL B 2 479 ? -3.421 -8.694 -76.859 1.00 64.49 ? 479 VAL C N 1 +ATOM 6127 C CA . VAL B 2 479 ? -3.913 -7.398 -77.309 1.00 59.86 ? 479 VAL C CA 1 +ATOM 6128 C C . VAL B 2 479 ? -3.062 -6.914 -78.474 1.00 65.87 ? 479 VAL C C 1 +ATOM 6129 O O . VAL B 2 479 ? -1.957 -7.403 -78.724 1.00 67.05 ? 479 VAL C O 1 +ATOM 6130 C CB . VAL B 2 479 ? -3.903 -6.335 -76.189 1.00 57.94 ? 479 VAL C CB 1 +ATOM 6131 C CG1 . VAL B 2 479 ? -5.075 -6.543 -75.254 1.00 61.87 ? 479 VAL C CG1 1 +ATOM 6132 C CG2 . VAL B 2 479 ? -2.578 -6.363 -75.437 1.00 62.67 ? 479 VAL C CG2 1 +ATOM 6133 N N . LYS B 2 480 ? -3.593 -5.917 -79.170 1.00 68.19 ? 480 LYS C N 1 +ATOM 6134 C CA . LYS B 2 480 ? -2.899 -5.304 -80.288 1.00 66.97 ? 480 LYS C CA 1 +ATOM 6135 C C . LYS B 2 480 ? -1.883 -4.310 -79.746 1.00 69.25 ? 480 LYS C C 1 +ATOM 6136 O O . LYS B 2 480 ? -2.232 -3.416 -78.967 1.00 66.86 ? 480 LYS C O 1 +ATOM 6137 C CB . LYS B 2 480 ? -3.910 -4.613 -81.205 1.00 64.60 ? 480 LYS C CB 1 +ATOM 6138 C CG . LYS B 2 480 ? -3.352 -4.116 -82.522 1.00 72.24 ? 480 LYS C CG 1 +ATOM 6139 C CD . LYS B 2 480 ? -4.436 -3.425 -83.336 1.00 67.37 ? 480 LYS C CD 1 +ATOM 6140 C CE . LYS B 2 480 ? -5.605 -4.361 -83.599 1.00 59.15 ? 480 LYS C CE 1 +ATOM 6141 N NZ . LYS B 2 480 ? -6.726 -3.664 -84.289 1.00 58.86 ? 480 LYS C NZ 1 +ATOM 6142 N N . ARG B 2 481 ? -0.623 -4.466 -80.161 1.00 69.67 ? 481 ARG C N 1 +ATOM 6143 C CA . ARG B 2 481 ? 0.427 -3.599 -79.634 1.00 69.38 ? 481 ARG C CA 1 +ATOM 6144 C C . ARG B 2 481 ? 0.092 -2.132 -79.872 1.00 69.32 ? 481 ARG C C 1 +ATOM 6145 O O . ARG B 2 481 ? 0.352 -1.278 -79.013 1.00 64.33 ? 481 ARG C O 1 +ATOM 6146 C CB . ARG B 2 481 ? 1.776 -3.953 -80.260 1.00 65.79 ? 481 ARG C CB 1 +ATOM 6147 C CG . ARG B 2 481 ? 2.897 -3.061 -79.761 1.00 73.50 ? 481 ARG C CG 1 +ATOM 6148 C CD . ARG B 2 481 ? 4.253 -3.422 -80.334 1.00 84.09 ? 481 ARG C CD 1 +ATOM 6149 N NE . ARG B 2 481 ? 5.278 -2.493 -79.860 1.00 83.91 ? 481 ARG C NE 1 +ATOM 6150 C CZ . ARG B 2 481 ? 6.573 -2.592 -80.144 1.00 88.06 ? 481 ARG C CZ 1 +ATOM 6151 N NH1 . ARG B 2 481 ? 7.426 -1.695 -79.667 1.00 86.20 ? 481 ARG C NH1 1 +ATOM 6152 N NH2 . ARG B 2 481 ? 7.015 -3.589 -80.901 1.00 83.15 ? 481 ARG C NH2 1 +ATOM 6153 N N . SER B 2 482 ? -0.532 -1.832 -81.016 1.00 64.47 ? 482 SER C N 1 +ATOM 6154 C CA . SER B 2 482 ? -0.972 -0.471 -81.302 1.00 61.86 ? 482 SER C CA 1 +ATOM 6155 C C . SER B 2 482 ? -1.859 0.073 -80.189 1.00 60.94 ? 482 SER C C 1 +ATOM 6156 O O . SER B 2 482 ? -1.706 1.226 -79.769 1.00 57.44 ? 482 SER C O 1 +ATOM 6157 C CB . SER B 2 482 ? -1.710 -0.445 -82.639 1.00 56.46 ? 482 SER C CB 1 +ATOM 6158 O OG . SER B 2 482 ? -2.250 0.837 -82.901 1.00 65.03 ? 482 SER C OG 1 +ATOM 6159 N N . THR B 2 483 ? -2.779 -0.747 -79.687 1.00 61.44 ? 483 THR C N 1 +ATOM 6160 C CA . THR B 2 483 ? -3.694 -0.286 -78.651 1.00 63.59 ? 483 THR C CA 1 +ATOM 6161 C C . THR B 2 483 ? -3.044 -0.287 -77.272 1.00 67.94 ? 483 THR C C 1 +ATOM 6162 O O . THR B 2 483 ? -3.394 0.547 -76.429 1.00 64.11 ? 483 THR C O 1 +ATOM 6163 C CB . THR B 2 483 ? -4.958 -1.145 -78.648 1.00 62.76 ? 483 THR C CB 1 +ATOM 6164 O OG1 . THR B 2 483 ? -4.661 -2.434 -78.101 1.00 65.27 ? 483 THR C OG1 1 +ATOM 6165 C CG2 . THR B 2 483 ? -5.478 -1.313 -80.068 1.00 57.63 ? 483 THR C CG2 1 +ATOM 6166 N N . TYR B 2 484 ? -2.118 -1.216 -77.018 1.00 71.08 ? 484 TYR C N 1 +ATOM 6167 C CA . TYR B 2 484 ? -1.455 -1.270 -75.718 1.00 65.58 ? 484 TYR C CA 1 +ATOM 6168 C C . TYR B 2 484 ? -0.666 0.005 -75.458 1.00 64.06 ? 484 TYR C C 1 +ATOM 6169 O O . TYR B 2 484 ? -0.791 0.624 -74.394 1.00 59.06 ? 484 TYR C O 1 +ATOM 6170 C CB . TYR B 2 484 ? -0.535 -2.489 -75.648 1.00 61.11 ? 484 TYR C CB 1 +ATOM 6171 C CG . TYR B 2 484 ? -0.132 -2.881 -74.243 1.00 65.93 ? 484 TYR C CG 1 +ATOM 6172 C CD1 . TYR B 2 484 ? -0.669 -2.238 -73.135 1.00 71.97 ? 484 TYR C CD1 1 +ATOM 6173 C CD2 . TYR B 2 484 ? 0.800 -3.886 -74.024 1.00 66.65 ? 484 TYR C CD2 1 +ATOM 6174 C CE1 . TYR B 2 484 ? -0.299 -2.594 -71.847 1.00 75.70 ? 484 TYR C CE1 1 +ATOM 6175 C CE2 . TYR B 2 484 ? 1.178 -4.250 -72.743 1.00 74.06 ? 484 TYR C CE2 1 +ATOM 6176 C CZ . TYR B 2 484 ? 0.624 -3.602 -71.658 1.00 75.93 ? 484 TYR C CZ 1 +ATOM 6177 O OH . TYR B 2 484 ? 0.994 -3.960 -70.381 1.00 75.82 ? 484 TYR C OH 1 +ATOM 6178 N N . LEU B 2 485 ? 0.159 0.408 -76.425 1.00 60.65 ? 485 LEU C N 1 +ATOM 6179 C CA . LEU B 2 485 ? 0.932 1.634 -76.275 1.00 60.08 ? 485 LEU C CA 1 +ATOM 6180 C C . LEU B 2 485 ? 0.027 2.854 -76.131 1.00 60.97 ? 485 LEU C C 1 +ATOM 6181 O O . LEU B 2 485 ? 0.347 3.775 -75.372 1.00 62.08 ? 485 LEU C O 1 +ATOM 6182 C CB . LEU B 2 485 ? 1.883 1.780 -77.465 1.00 58.68 ? 485 LEU C CB 1 +ATOM 6183 C CG . LEU B 2 485 ? 2.889 0.634 -77.637 1.00 61.49 ? 485 LEU C CG 1 +ATOM 6184 C CD1 . LEU B 2 485 ? 3.784 0.849 -78.849 1.00 57.24 ? 485 LEU C CD1 1 +ATOM 6185 C CD2 . LEU B 2 485 ? 3.735 0.465 -76.378 1.00 66.21 ? 485 LEU C CD2 1 +ATOM 6186 N N . ARG B 2 486 ? -1.125 2.860 -76.812 1.00 60.45 ? 486 ARG C N 1 +ATOM 6187 C CA . ARG B 2 486 ? -2.086 3.948 -76.641 1.00 60.21 ? 486 ARG C CA 1 +ATOM 6188 C C . ARG B 2 486 ? -2.638 3.978 -75.222 1.00 60.05 ? 486 ARG C C 1 +ATOM 6189 O O . ARG B 2 486 ? -2.617 5.020 -74.557 1.00 59.59 ? 486 ARG C O 1 +ATOM 6190 C CB . ARG B 2 486 ? -3.238 3.807 -77.636 1.00 61.86 ? 486 ARG C CB 1 +ATOM 6191 C CG . ARG B 2 486 ? -2.929 4.175 -79.069 1.00 59.60 ? 486 ARG C CG 1 +ATOM 6192 C CD . ARG B 2 486 ? -4.228 4.360 -79.831 1.00 60.47 ? 486 ARG C CD 1 +ATOM 6193 N NE . ARG B 2 486 ? -4.422 3.330 -80.843 1.00 61.21 ? 486 ARG C NE 1 +ATOM 6194 C CZ . ARG B 2 486 ? -4.016 3.438 -82.102 1.00 64.76 ? 486 ARG C CZ 1 +ATOM 6195 N NH1 . ARG B 2 486 ? -3.388 4.532 -82.511 1.00 66.17 ? 486 ARG C NH1 1 +ATOM 6196 N NH2 . ARG B 2 486 ? -4.236 2.450 -82.955 1.00 68.03 ? 486 ARG C NH2 1 +ATOM 6197 N N . LEU B 2 487 ? -3.159 2.839 -74.754 1.00 61.75 ? 487 LEU C N 1 +ATOM 6198 C CA . LEU B 2 487 ? -3.782 2.768 -73.434 1.00 68.26 ? 487 LEU C CA 1 +ATOM 6199 C C . LEU B 2 487 ? -2.825 3.204 -72.330 1.00 72.99 ? 487 LEU C C 1 +ATOM 6200 O O . LEU B 2 487 ? -3.246 3.816 -71.339 1.00 66.48 ? 487 LEU C O 1 +ATOM 6201 C CB . LEU B 2 487 ? -4.287 1.349 -73.179 1.00 68.64 ? 487 LEU C CB 1 +ATOM 6202 C CG . LEU B 2 487 ? -5.411 0.894 -74.108 1.00 60.99 ? 487 LEU C CG 1 +ATOM 6203 C CD1 . LEU B 2 487 ? -5.889 -0.502 -73.743 1.00 57.79 ? 487 LEU C CD1 1 +ATOM 6204 C CD2 . LEU B 2 487 ? -6.555 1.896 -74.057 1.00 56.74 ? 487 LEU C CD2 1 +ATOM 6205 N N . GLN B 2 488 ? -1.539 2.866 -72.466 1.00 74.04 ? 488 GLN C N 1 +ATOM 6206 C CA . GLN B 2 488 ? -0.534 3.396 -71.549 1.00 72.44 ? 488 GLN C CA 1 +ATOM 6207 C C . GLN B 2 488 ? -0.438 4.910 -71.672 1.00 69.41 ? 488 GLN C C 1 +ATOM 6208 O O . GLN B 2 488 ? -0.442 5.631 -70.668 1.00 70.48 ? 488 GLN C O 1 +ATOM 6209 C CB . GLN B 2 488 ? 0.824 2.752 -71.831 1.00 70.27 ? 488 GLN C CB 1 +ATOM 6210 C CG . GLN B 2 488 ? 0.903 1.274 -71.487 1.00 74.28 ? 488 GLN C CG 1 +ATOM 6211 C CD . GLN B 2 488 ? 2.156 0.610 -72.031 1.00 77.32 ? 488 GLN C CD 1 +ATOM 6212 O OE1 . GLN B 2 488 ? 2.697 1.021 -73.063 1.00 77.11 ? 488 GLN C OE1 1 +ATOM 6213 N NE2 . GLN B 2 488 ? 2.629 -0.417 -71.333 1.00 68.16 ? 488 GLN C NE2 1 +ATOM 6214 N N . LEU B 2 489 ? -0.380 5.406 -72.909 1.00 62.83 ? 489 LEU C N 1 +ATOM 6215 C CA . LEU B 2 489 ? -0.267 6.837 -73.149 1.00 58.28 ? 489 LEU C CA 1 +ATOM 6216 C C . LEU B 2 489 ? -1.486 7.599 -72.645 1.00 63.24 ? 489 LEU C C 1 +ATOM 6217 O O . LEU B 2 489 ? -1.361 8.744 -72.195 1.00 67.45 ? 489 LEU C O 1 +ATOM 6218 C CB . LEU B 2 489 ? -0.076 7.079 -74.638 1.00 59.45 ? 489 LEU C CB 1 +ATOM 6219 C CG . LEU B 2 489 ? 0.208 8.523 -75.011 1.00 71.45 ? 489 LEU C CG 1 +ATOM 6220 C CD1 . LEU B 2 489 ? 1.633 8.880 -74.618 1.00 70.41 ? 489 LEU C CD1 1 +ATOM 6221 C CD2 . LEU B 2 489 ? -0.051 8.747 -76.491 1.00 77.64 ? 489 LEU C CD2 1 +ATOM 6222 N N . LEU B 2 490 ? -2.668 6.995 -72.728 1.00 63.49 ? 490 LEU C N 1 +ATOM 6223 C CA . LEU B 2 490 ? -3.896 7.624 -72.259 1.00 66.22 ? 490 LEU C CA 1 +ATOM 6224 C C . LEU B 2 490 ? -4.079 7.547 -70.750 1.00 66.61 ? 490 LEU C C 1 +ATOM 6225 O O . LEU B 2 490 ? -5.157 7.890 -70.259 1.00 67.08 ? 490 LEU C O 1 +ATOM 6226 C CB . LEU B 2 490 ? -5.107 6.995 -72.949 1.00 70.55 ? 490 LEU C CB 1 +ATOM 6227 C CG . LEU B 2 490 ? -5.481 7.519 -74.340 1.00 73.08 ? 490 LEU C CG 1 +ATOM 6228 C CD1 . LEU B 2 490 ? -4.842 8.873 -74.600 1.00 79.17 ? 490 LEU C CD1 1 +ATOM 6229 C CD2 . LEU B 2 490 ? -5.123 6.526 -75.434 1.00 69.85 ? 490 LEU C CD2 1 +ATOM 6230 N N . ALA B 2 491 ? -3.074 7.102 -70.004 1.00 67.14 ? 491 ALA C N 1 +ATOM 6231 C CA . ALA B 2 491 ? -3.151 7.061 -68.553 1.00 62.76 ? 491 ALA C CA 1 +ATOM 6232 C C . ALA B 2 491 ? -2.205 8.052 -67.899 1.00 75.29 ? 491 ALA C C 1 +ATOM 6233 O O . ALA B 2 491 ? -2.187 8.149 -66.668 1.00 81.69 ? 491 ALA C O 1 +ATOM 6234 C CB . ALA B 2 491 ? -2.859 5.646 -68.044 1.00 61.94 ? 491 ALA C CB 1 +ATOM 6235 N N . LYS B 2 492 ? -1.436 8.801 -68.694 1.00 84.40 ? 492 LYS C N 1 +ATOM 6236 C CA . LYS B 2 492 ? -0.470 9.774 -68.193 1.00 82.63 ? 492 LYS C CA 1 +ATOM 6237 C C . LYS B 2 492 ? -1.147 11.110 -67.918 1.00 87.43 ? 492 LYS C C 1 +ATOM 6238 O O . LYS B 2 492 ? -2.051 11.524 -68.649 1.00 91.53 ? 492 LYS C O 1 +ATOM 6239 C CB . LYS B 2 492 ? 0.674 9.961 -69.195 1.00 64.01 ? 492 LYS C CB 1 +ATOM 6240 C CG . LYS B 2 492 ? 1.835 9.005 -68.986 1.00 60.84 ? 492 LYS C CG 1 +ATOM 6241 C CD . LYS B 2 492 ? 1.412 7.564 -69.170 1.00 62.75 ? 492 LYS C CD 1 +ATOM 6242 C CE . LYS B 2 492 ? 2.403 6.598 -68.530 1.00 74.95 ? 492 LYS C CE 1 +ATOM 6243 N NZ . LYS B 2 492 ? 1.868 5.202 -68.445 1.00 58.38 ? 492 LYS C NZ 1 +ATOM 6244 N N . GLU B 2 493 ? -0.695 11.788 -66.859 1.00 86.06 ? 493 GLU C N 1 +ATOM 6245 C CA . GLU B 2 493 ? -1.365 13.013 -66.432 1.00 91.71 ? 493 GLU C CA 1 +ATOM 6246 C C . GLU B 2 493 ? -1.331 14.089 -67.513 1.00 93.15 ? 493 GLU C C 1 +ATOM 6247 O O . GLU B 2 493 ? -2.262 14.897 -67.607 1.00 94.21 ? 493 GLU C O 1 +ATOM 6248 C CB . GLU B 2 493 ? -0.737 13.530 -65.134 1.00 94.93 ? 493 GLU C CB 1 +ATOM 6249 C CG . GLU B 2 493 ? -1.693 13.530 -63.941 1.00 93.41 ? 493 GLU C CG 1 +ATOM 6250 C CD . GLU B 2 493 ? -2.760 14.611 -64.035 1.00 95.03 ? 493 GLU C CD 1 +ATOM 6251 O OE1 . GLU B 2 493 ? -2.545 15.603 -64.768 1.00 89.33 ? 493 GLU C OE1 1 +ATOM 6252 O OE2 . GLU B 2 493 ? -3.818 14.462 -63.386 1.00 95.00 ? 493 GLU C OE2 1 +ATOM 6253 N N . GLU B 2 494 ? -0.290 14.102 -68.354 1.00 93.49 ? 494 GLU C N 1 +ATOM 6254 C CA . GLU B 2 494 ? -0.233 15.086 -69.431 1.00 92.50 ? 494 GLU C CA 1 +ATOM 6255 C C . GLU B 2 494 ? -1.286 14.813 -70.494 1.00 91.82 ? 494 GLU C C 1 +ATOM 6256 O O . GLU B 2 494 ? -1.749 15.745 -71.162 1.00 96.77 ? 494 GLU C O 1 +ATOM 6257 C CB . GLU B 2 494 ? 1.155 15.111 -70.072 1.00 85.60 ? 494 GLU C CB 1 +ATOM 6258 C CG . GLU B 2 494 ? 1.758 13.748 -70.368 1.00 80.62 ? 494 GLU C CG 1 +ATOM 6259 C CD . GLU B 2 494 ? 2.628 13.232 -69.236 1.00 88.53 ? 494 GLU C CD 1 +ATOM 6260 O OE1 . GLU B 2 494 ? 2.111 13.054 -68.110 1.00 83.16 ? 494 GLU C OE1 1 +ATOM 6261 O OE2 . GLU B 2 494 ? 3.842 13.038 -69.470 1.00 94.04 ? 494 GLU C OE2 1 +ATOM 6262 N N . TYR B 2 495 ? -1.665 13.551 -70.674 1.00 88.98 ? 495 TYR C N 1 +ATOM 6263 C CA . TYR B 2 495 ? -2.695 13.193 -71.637 1.00 86.24 ? 495 TYR C CA 1 +ATOM 6264 C C . TYR B 2 495 ? -3.954 12.729 -70.917 1.00 85.14 ? 495 TYR C C 1 +ATOM 6265 O O . TYR B 2 495 ? -4.908 13.500 -70.770 1.00 85.27 ? 495 TYR C O 1 +ATOM 6266 C CB . TYR B 2 495 ? -2.164 12.122 -72.588 1.00 75.88 ? 495 TYR C CB 1 +ATOM 6267 C CG . TYR B 2 495 ? -1.134 12.657 -73.553 1.00 77.20 ? 495 TYR C CG 1 +ATOM 6268 C CD1 . TYR B 2 495 ? -0.911 14.024 -73.679 1.00 85.62 ? 495 TYR C CD1 1 +ATOM 6269 C CD2 . TYR B 2 495 ? -0.361 11.800 -74.312 1.00 75.24 ? 495 TYR C CD2 1 +ATOM 6270 C CE1 . TYR B 2 495 ? 0.037 14.518 -74.557 1.00 89.33 ? 495 TYR C CE1 1 +ATOM 6271 C CE2 . TYR B 2 495 ? 0.593 12.280 -75.188 1.00 80.56 ? 495 TYR C CE2 1 +ATOM 6272 C CZ . TYR B 2 495 ? 0.788 13.638 -75.309 1.00 87.23 ? 495 TYR C CZ 1 +ATOM 6273 O OH . TYR B 2 495 ? 1.740 14.106 -76.187 1.00 81.89 ? 495 TYR C OH 1 +ATOM 6274 N N . LYS B 2 496 ? -3.953 11.473 -70.466 1.00 83.08 ? 496 LYS C N 1 +ATOM 6275 C CA . LYS B 2 496 ? -5.021 10.880 -69.664 1.00 83.11 ? 496 LYS C CA 1 +ATOM 6276 C C . LYS B 2 496 ? -6.357 10.905 -70.399 1.00 78.67 ? 496 LYS C C 1 +ATOM 6277 O O . LYS B 2 496 ? -6.462 11.430 -71.510 1.00 77.83 ? 496 LYS C O 1 +ATOM 6278 C CB . LYS B 2 496 ? -5.129 11.565 -68.290 1.00 84.25 ? 496 LYS C CB 1 +ATOM 6279 C CG . LYS B 2 496 ? -6.195 12.645 -68.137 1.00 79.25 ? 496 LYS C CG 1 +ATOM 6280 C CD . LYS B 2 496 ? -6.137 13.261 -66.745 1.00 83.24 ? 496 LYS C CD 1 +ATOM 6281 C CE . LYS B 2 496 ? -6.142 12.186 -65.662 1.00 81.64 ? 496 LYS C CE 1 +ATOM 6282 N NZ . LYS B 2 496 ? -5.984 12.748 -64.291 1.00 76.54 ? 496 LYS C NZ 1 +ATOM 6283 N N . LEU B 2 497 ? -7.380 10.306 -69.802 1.00 73.78 ? 497 LEU C N 1 +ATOM 6284 C CA . LEU B 2 497 ? -8.663 10.176 -70.470 1.00 69.85 ? 497 LEU C CA 1 +ATOM 6285 C C . LEU B 2 497 ? -9.640 11.276 -70.095 1.00 66.73 ? 497 LEU C C 1 +ATOM 6286 O O . LEU B 2 497 ? -10.306 11.827 -70.975 1.00 68.70 ? 497 LEU C O 1 +ATOM 6287 C CB . LEU B 2 497 ? -9.276 8.810 -70.156 1.00 70.58 ? 497 LEU C CB 1 +ATOM 6288 C CG . LEU B 2 497 ? -9.518 7.907 -71.363 1.00 60.50 ? 497 LEU C CG 1 +ATOM 6289 C CD1 . LEU B 2 497 ? -10.797 8.307 -72.041 1.00 60.94 ? 497 LEU C CD1 1 +ATOM 6290 C CD2 . LEU B 2 497 ? -8.367 8.008 -72.334 1.00 56.01 ? 497 LEU C CD2 1 +ATOM 6291 N N . SER B 2 498 ? -9.731 11.616 -68.810 1.00 68.99 ? 498 SER C N 1 +ATOM 6292 C CA . SER B 2 498 ? -10.719 12.597 -68.380 1.00 72.68 ? 498 SER C CA 1 +ATOM 6293 C C . SER B 2 498 ? -10.503 13.925 -69.091 1.00 76.45 ? 498 SER C C 1 +ATOM 6294 O O . SER B 2 498 ? -11.430 14.475 -69.699 1.00 71.71 ? 498 SER C O 1 +ATOM 6295 C CB . SER B 2 498 ? -10.657 12.771 -66.862 1.00 79.20 ? 498 SER C CB 1 +ATOM 6296 O OG . SER B 2 498 ? -9.388 13.250 -66.446 1.00 80.28 ? 498 SER C OG 1 +ATOM 6297 N N . SER B 2 499 ? -9.266 14.433 -69.058 1.00 83.23 ? 499 SER C N 1 +ATOM 6298 C CA . SER B 2 499 ? -8.954 15.709 -69.698 1.00 88.38 ? 499 SER C CA 1 +ATOM 6299 C C . SER B 2 499 ? -9.070 15.624 -71.215 1.00 87.27 ? 499 SER C C 1 +ATOM 6300 O O . SER B 2 499 ? -9.403 16.619 -71.870 1.00 84.98 ? 499 SER C O 1 +ATOM 6301 C CB . SER B 2 499 ? -7.549 16.168 -69.295 1.00 90.33 ? 499 SER C CB 1 +ATOM 6302 O OG . SER B 2 499 ? -6.550 15.285 -69.783 1.00 88.73 ? 499 SER C OG 1 +ATOM 6303 N N . LEU B 2 500 ? -8.813 14.451 -71.788 1.00 80.43 ? 500 LEU C N 1 +ATOM 6304 C CA . LEU B 2 500 ? -9.009 14.279 -73.219 1.00 69.74 ? 500 LEU C CA 1 +ATOM 6305 C C . LEU B 2 500 ? -10.479 14.113 -73.567 1.00 69.07 ? 500 LEU C C 1 +ATOM 6306 O O . LEU B 2 500 ? -10.912 14.555 -74.636 1.00 72.55 ? 500 LEU C O 1 +ATOM 6307 C CB . LEU B 2 500 ? -8.213 13.074 -73.710 1.00 59.71 ? 500 LEU C CB 1 +ATOM 6308 C CG . LEU B 2 500 ? -6.764 13.422 -74.022 1.00 68.98 ? 500 LEU C CG 1 +ATOM 6309 C CD1 . LEU B 2 500 ? -6.001 12.202 -74.477 1.00 66.92 ? 500 LEU C CD1 1 +ATOM 6310 C CD2 . LEU B 2 500 ? -6.725 14.502 -75.075 1.00 78.29 ? 500 LEU C CD2 1 +ATOM 6311 N N . MET B 2 501 ? -11.260 13.501 -72.678 1.00 67.65 ? 501 MET C N 1 +ATOM 6312 C CA . MET B 2 501 ? -12.660 13.251 -72.990 1.00 66.29 ? 501 MET C CA 1 +ATOM 6313 C C . MET B 2 501 ? -13.522 14.479 -72.739 1.00 65.21 ? 501 MET C C 1 +ATOM 6314 O O . MET B 2 501 ? -14.424 14.771 -73.528 1.00 64.96 ? 501 MET C O 1 +ATOM 6315 C CB . MET B 2 501 ? -13.168 12.051 -72.191 1.00 70.63 ? 501 MET C CB 1 +ATOM 6316 C CG . MET B 2 501 ? -14.494 11.464 -72.669 1.00 67.60 ? 501 MET C CG 1 +ATOM 6317 S SD . MET B 2 501 ? -14.486 10.672 -74.305 1.00 67.24 ? 501 MET C SD 1 +ATOM 6318 C CE . MET B 2 501 ? -12.792 10.097 -74.473 1.00 55.49 ? 501 MET C CE 1 +ATOM 6319 N N . GLU B 2 502 ? -13.273 15.212 -71.652 1.00 70.49 ? 502 GLU C N 1 +ATOM 6320 C CA . GLU B 2 502 ? -14.035 16.437 -71.438 1.00 78.27 ? 502 GLU C CA 1 +ATOM 6321 C C . GLU B 2 502 ? -13.680 17.514 -72.456 1.00 80.57 ? 502 GLU C C 1 +ATOM 6322 O O . GLU B 2 502 ? -14.480 18.431 -72.675 1.00 78.36 ? 502 GLU C O 1 +ATOM 6323 C CB . GLU B 2 502 ? -13.820 16.964 -70.019 1.00 75.84 ? 502 GLU C CB 1 +ATOM 6324 C CG . GLU B 2 502 ? -12.459 17.587 -69.783 1.00 68.25 ? 502 GLU C CG 1 +ATOM 6325 C CD . GLU B 2 502 ? -12.335 18.193 -68.401 1.00 69.73 ? 502 GLU C CD 1 +ATOM 6326 O OE1 . GLU B 2 502 ? -13.356 18.268 -67.680 1.00 64.58 ? 502 GLU C OE1 1 +ATOM 6327 O OE2 . GLU B 2 502 ? -11.211 18.596 -68.038 1.00 68.08 ? 502 GLU C OE2 1 +ATOM 6328 N N . GLU B 2 503 ? -12.513 17.417 -73.095 1.00 75.32 ? 503 GLU C N 1 +ATOM 6329 C CA . GLU B 2 503 ? -12.169 18.363 -74.150 1.00 75.16 ? 503 GLU C CA 1 +ATOM 6330 C C . GLU B 2 503 ? -13.102 18.196 -75.341 1.00 73.77 ? 503 GLU C C 1 +ATOM 6331 O O . GLU B 2 503 ? -13.859 19.110 -75.686 1.00 72.77 ? 503 GLU C O 1 +ATOM 6332 C CB . GLU B 2 503 ? -10.712 18.171 -74.580 1.00 85.34 ? 503 GLU C CB 1 +ATOM 6333 C CG . GLU B 2 503 ? -10.322 18.945 -75.840 1.00 94.92 ? 503 GLU C CG 1 +ATOM 6334 C CD . GLU B 2 503 ? -9.552 20.230 -75.552 1.00 110.75 ? 503 GLU C CD 1 +ATOM 6335 O OE1 . GLU B 2 503 ? -8.373 20.149 -75.133 1.00 98.13 ? 503 GLU C OE1 1 +ATOM 6336 O OE2 . GLU B 2 503 ? -10.127 21.323 -75.749 1.00 120.47 ? 503 GLU C OE2 1 +ATOM 6337 N N . SER B 2 504 ? -13.090 17.011 -75.959 1.00 68.67 ? 504 SER C N 1 +ATOM 6338 C CA . SER B 2 504 ? -13.878 16.803 -77.170 1.00 68.25 ? 504 SER C CA 1 +ATOM 6339 C C . SER B 2 504 ? -15.375 16.765 -76.874 1.00 62.87 ? 504 SER C C 1 +ATOM 6340 O O . SER B 2 504 ? -16.173 17.311 -77.645 1.00 68.47 ? 504 SER C O 1 +ATOM 6341 C CB . SER B 2 504 ? -13.419 15.529 -77.878 1.00 54.39 ? 504 SER C CB 1 +ATOM 6342 O OG . SER B 2 504 ? -13.486 14.412 -77.017 1.00 52.47 ? 504 SER C OG 1 +ATOM 6343 N N . LEU B 2 505 ? -15.779 16.162 -75.753 1.00 58.07 ? 505 LEU C N 1 +ATOM 6344 C CA . LEU B 2 505 ? -17.191 16.181 -75.388 1.00 62.77 ? 505 LEU C CA 1 +ATOM 6345 C C . LEU B 2 505 ? -17.689 17.592 -75.138 1.00 71.36 ? 505 LEU C C 1 +ATOM 6346 O O . LEU B 2 505 ? -18.903 17.829 -75.162 1.00 70.08 ? 505 LEU C O 1 +ATOM 6347 C CB . LEU B 2 505 ? -17.432 15.338 -74.139 1.00 67.05 ? 505 LEU C CB 1 +ATOM 6348 C CG . LEU B 2 505 ? -17.331 13.827 -74.315 1.00 66.40 ? 505 LEU C CG 1 +ATOM 6349 C CD1 . LEU B 2 505 ? -17.601 13.116 -73.002 1.00 67.10 ? 505 LEU C CD1 1 +ATOM 6350 C CD2 . LEU B 2 505 ? -18.294 13.361 -75.388 1.00 61.64 ? 505 LEU C CD2 1 +ATOM 6351 N N . LEU B 2 506 ? -16.775 18.537 -74.913 1.00 72.01 ? 506 LEU C N 1 +ATOM 6352 C CA . LEU B 2 506 ? -17.172 19.924 -74.736 1.00 78.13 ? 506 LEU C CA 1 +ATOM 6353 C C . LEU B 2 506 ? -17.639 20.548 -76.044 1.00 69.69 ? 506 LEU C C 1 +ATOM 6354 O O . LEU B 2 506 ? -18.317 21.580 -76.020 1.00 77.82 ? 506 LEU C O 1 +ATOM 6355 C CB . LEU B 2 506 ? -16.007 20.723 -74.142 1.00 81.44 ? 506 LEU C CB 1 +ATOM 6356 C CG . LEU B 2 506 ? -16.283 22.109 -73.554 1.00 84.89 ? 506 LEU C CG 1 +ATOM 6357 C CD1 . LEU B 2 506 ? -17.125 21.991 -72.295 1.00 63.56 ? 506 LEU C CD1 1 +ATOM 6358 C CD2 . LEU B 2 506 ? -14.978 22.858 -73.273 1.00 79.59 ? 506 LEU C CD2 1 +ATOM 6359 N N . GLN B 2 507 ? -17.329 19.932 -77.179 1.00 60.04 ? 507 GLN C N 1 +ATOM 6360 C CA . GLN B 2 507 ? -17.771 20.457 -78.464 1.00 68.93 ? 507 GLN C CA 1 +ATOM 6361 C C . GLN B 2 507 ? -19.020 19.695 -78.913 1.00 69.33 ? 507 GLN C C 1 +ATOM 6362 O O . GLN B 2 507 ? -19.004 18.868 -79.823 1.00 78.26 ? 507 GLN C O 1 +ATOM 6363 C CB . GLN B 2 507 ? -16.637 20.389 -79.487 1.00 62.93 ? 507 GLN C CB 1 +ATOM 6364 C CG . GLN B 2 507 ? -16.986 20.927 -80.874 1.00 71.59 ? 507 GLN C CG 1 +ATOM 6365 C CD . GLN B 2 507 ? -17.749 22.252 -80.850 1.00 84.04 ? 507 GLN C CD 1 +ATOM 6366 O OE1 . GLN B 2 507 ? -17.368 23.201 -80.159 1.00 86.16 ? 507 GLN C OE1 1 +ATOM 6367 N NE2 . GLN B 2 507 ? -18.841 22.313 -81.609 1.00 80.80 ? 507 GLN C NE2 1 +ATOM 6368 N N . ASP B 2 508 ? -20.120 19.976 -78.218 1.00 61.87 ? 508 ASP C N 1 +ATOM 6369 C CA . ASP B 2 508 ? -21.414 19.407 -78.565 1.00 61.70 ? 508 ASP C CA 1 +ATOM 6370 C C . ASP B 2 508 ? -22.505 20.242 -77.916 1.00 64.61 ? 508 ASP C C 1 +ATOM 6371 O O . ASP B 2 508 ? -22.382 20.629 -76.751 1.00 69.03 ? 508 ASP C O 1 +ATOM 6372 C CB . ASP B 2 508 ? -21.532 17.945 -78.116 1.00 62.76 ? 508 ASP C CB 1 +ATOM 6373 C CG . ASP B 2 508 ? -22.701 17.224 -78.776 1.00 66.11 ? 508 ASP C CG 1 +ATOM 6374 O OD1 . ASP B 2 508 ? -23.348 17.820 -79.663 1.00 67.55 ? 508 ASP C OD1 1 +ATOM 6375 O OD2 . ASP B 2 508 ? -22.976 16.061 -78.411 1.00 64.95 ? 508 ASP C OD2 1 +ATOM 6376 N N . ARG B 2 509 ? -23.579 20.500 -78.664 1.00 60.21 ? 509 ARG C N 1 +ATOM 6377 C CA . ARG B 2 509 ? -24.686 21.288 -78.133 1.00 59.67 ? 509 ARG C CA 1 +ATOM 6378 C C . ARG B 2 509 ? -25.454 20.484 -77.093 1.00 63.37 ? 509 ARG C C 1 +ATOM 6379 O O . ARG B 2 509 ? -26.686 20.530 -77.043 1.00 71.44 ? 509 ARG C O 1 +ATOM 6380 C CB . ARG B 2 509 ? -25.629 21.736 -79.250 1.00 67.89 ? 509 ARG C CB 1 +ATOM 6381 C CG . ARG B 2 509 ? -26.533 22.904 -78.870 1.00 68.71 ? 509 ARG C CG 1 +ATOM 6382 C CD . ARG B 2 509 ? -27.881 22.794 -79.558 1.00 70.64 ? 509 ARG C CD 1 +ATOM 6383 N NE . ARG B 2 509 ? -28.903 23.591 -78.889 1.00 68.15 ? 509 ARG C NE 1 +ATOM 6384 C CZ . ARG B 2 509 ? -29.126 24.878 -79.137 1.00 73.79 ? 509 ARG C CZ 1 +ATOM 6385 N NH1 . ARG B 2 509 ? -30.077 25.524 -78.479 1.00 78.05 ? 509 ARG C NH1 1 +ATOM 6386 N NH2 . ARG B 2 509 ? -28.398 25.521 -80.041 1.00 75.80 ? 509 ARG C NH2 1 +ATOM 6387 N N . LEU B 2 510 ? -24.735 19.739 -76.264 1.00 64.25 ? 510 LEU C N 1 +ATOM 6388 C CA . LEU B 2 510 ? -25.361 18.934 -75.232 1.00 69.24 ? 510 LEU C CA 1 +ATOM 6389 C C . LEU B 2 510 ? -24.546 18.898 -73.947 1.00 72.18 ? 510 LEU C C 1 +ATOM 6390 O O . LEU B 2 510 ? -25.009 18.317 -72.960 1.00 69.68 ? 510 LEU C O 1 +ATOM 6391 C CB . LEU B 2 510 ? -25.599 17.506 -75.749 1.00 61.28 ? 510 LEU C CB 1 +ATOM 6392 C CG . LEU B 2 510 ? -27.044 16.993 -75.718 1.00 62.79 ? 510 LEU C CG 1 +ATOM 6393 C CD1 . LEU B 2 510 ? -27.633 17.239 -74.348 1.00 62.18 ? 510 LEU C CD1 1 +ATOM 6394 C CD2 . LEU B 2 510 ? -27.926 17.614 -76.793 1.00 52.73 ? 510 LEU C CD2 1 +ATOM 6395 N N . VAL B 2 511 ? -23.362 19.509 -73.929 1.00 72.55 ? 511 VAL C N 1 +ATOM 6396 C CA . VAL B 2 511 ? -22.458 19.503 -72.773 1.00 72.40 ? 511 VAL C CA 1 +ATOM 6397 C C . VAL B 2 511 ? -23.192 20.043 -71.546 1.00 72.03 ? 511 VAL C C 1 +ATOM 6398 O O . VAL B 2 511 ? -24.035 20.954 -71.681 1.00 73.18 ? 511 VAL C O 1 +ATOM 6399 C CB . VAL B 2 511 ? -21.187 20.322 -73.091 1.00 67.82 ? 511 VAL C CB 1 +ATOM 6400 C CG1 . VAL B 2 511 ? -21.455 21.829 -73.079 1.00 64.50 ? 511 VAL C CG1 1 +ATOM 6401 C CG2 . VAL B 2 511 ? -20.023 19.944 -72.177 1.00 63.26 ? 511 VAL C CG2 1 +ATOM 6402 N N . PRO B 2 512 ? -22.979 19.484 -70.338 1.00 67.15 ? 512 PRO C N 1 +ATOM 6403 C CA . PRO B 2 512 ? -22.104 18.339 -70.075 1.00 60.89 ? 512 PRO C CA 1 +ATOM 6404 C C . PRO B 2 512 ? -22.798 17.038 -70.449 1.00 73.56 ? 512 PRO C C 1 +ATOM 6405 O O . PRO B 2 512 ? -23.808 16.678 -69.839 1.00 77.42 ? 512 PRO C O 1 +ATOM 6406 C CB . PRO B 2 512 ? -21.844 18.425 -68.564 1.00 49.27 ? 512 PRO C CB 1 +ATOM 6407 C CG . PRO B 2 512 ? -22.495 19.715 -68.103 1.00 58.31 ? 512 PRO C CG 1 +ATOM 6408 C CD . PRO B 2 512 ? -23.572 19.994 -69.095 1.00 58.43 ? 512 PRO C CD 1 +ATOM 6409 N N . VAL B 2 513 ? -22.276 16.354 -71.469 1.00 67.25 ? 513 VAL C N 1 +ATOM 6410 C CA . VAL B 2 513 ? -22.881 15.092 -71.872 1.00 61.03 ? 513 VAL C CA 1 +ATOM 6411 C C . VAL B 2 513 ? -22.630 14.026 -70.820 1.00 59.06 ? 513 VAL C C 1 +ATOM 6412 O O . VAL B 2 513 ? -23.467 13.141 -70.605 1.00 57.76 ? 513 VAL C O 1 +ATOM 6413 C CB . VAL B 2 513 ? -22.353 14.676 -73.256 1.00 61.19 ? 513 VAL C CB 1 +ATOM 6414 C CG1 . VAL B 2 513 ? -22.639 15.769 -74.269 1.00 67.17 ? 513 VAL C CG1 1 +ATOM 6415 C CG2 . VAL B 2 513 ? -20.868 14.416 -73.197 1.00 50.10 ? 513 VAL C CG2 1 +ATOM 6416 N N . LEU B 2 514 ? -21.503 14.115 -70.120 1.00 56.75 ? 514 LEU C N 1 +ATOM 6417 C CA . LEU B 2 514 ? -21.147 13.190 -69.055 1.00 60.33 ? 514 LEU C CA 1 +ATOM 6418 C C . LEU B 2 514 ? -20.934 13.983 -67.777 1.00 64.92 ? 514 LEU C C 1 +ATOM 6419 O O . LEU B 2 514 ? -20.107 14.901 -67.746 1.00 64.52 ? 514 LEU C O 1 +ATOM 6420 C CB . LEU B 2 514 ? -19.883 12.403 -69.403 1.00 55.20 ? 514 LEU C CB 1 +ATOM 6421 C CG . LEU B 2 514 ? -19.996 11.290 -70.441 1.00 52.73 ? 514 LEU C CG 1 +ATOM 6422 C CD1 . LEU B 2 514 ? -18.662 10.570 -70.548 1.00 51.17 ? 514 LEU C CD1 1 +ATOM 6423 C CD2 . LEU B 2 514 ? -21.119 10.322 -70.087 1.00 49.10 ? 514 LEU C CD2 1 +ATOM 6424 N N . ILE B 2 515 ? -21.683 13.632 -66.730 1.00 63.90 ? 515 ILE C N 1 +ATOM 6425 C CA . ILE B 2 515 ? -21.397 14.180 -65.415 1.00 65.14 ? 515 ILE C CA 1 +ATOM 6426 C C . ILE B 2 515 ? -19.962 13.800 -65.039 1.00 65.12 ? 515 ILE C C 1 +ATOM 6427 O O . ILE B 2 515 ? -19.416 12.795 -65.511 1.00 67.50 ? 515 ILE C O 1 +ATOM 6428 C CB . ILE B 2 515 ? -22.417 13.675 -64.379 1.00 69.82 ? 515 ILE C CB 1 +ATOM 6429 C CG1 . ILE B 2 515 ? -22.368 14.523 -63.110 1.00 82.08 ? 515 ILE C CG1 1 +ATOM 6430 C CG2 . ILE B 2 515 ? -22.162 12.222 -64.033 1.00 72.82 ? 515 ILE C CG2 1 +ATOM 6431 C CD1 . ILE B 2 515 ? -22.782 15.959 -63.325 1.00 95.39 ? 515 ILE C CD1 1 +ATOM 6432 N N . LYS B 2 516 ? -19.334 14.633 -64.214 1.00 69.22 ? 516 LYS C N 1 +ATOM 6433 C CA . LYS B 2 516 ? -17.901 14.485 -63.957 1.00 76.97 ? 516 LYS C CA 1 +ATOM 6434 C C . LYS B 2 516 ? -17.479 13.122 -63.405 1.00 74.37 ? 516 LYS C C 1 +ATOM 6435 O O . LYS B 2 516 ? -16.388 12.656 -63.779 1.00 67.45 ? 516 LYS C O 1 +ATOM 6436 C CB . LYS B 2 516 ? -17.433 15.613 -63.026 1.00 84.66 ? 516 LYS C CB 1 +ATOM 6437 C CG . LYS B 2 516 ? -15.917 15.764 -62.956 1.00 78.54 ? 516 LYS C CG 1 +ATOM 6438 C CD . LYS B 2 516 ? -15.495 17.041 -62.245 1.00 71.70 ? 516 LYS C CD 1 +ATOM 6439 C CE . LYS B 2 516 ? -13.984 17.227 -62.336 1.00 75.74 ? 516 LYS C CE 1 +ATOM 6440 N NZ . LYS B 2 516 ? -13.516 18.511 -61.747 1.00 73.41 ? 516 LYS C NZ 1 +ATOM 6441 N N . PRO B 2 517 ? -18.245 12.446 -62.531 1.00 76.33 ? 517 PRO C N 1 +ATOM 6442 C CA . PRO B 2 517 ? -17.811 11.114 -62.063 1.00 73.20 ? 517 PRO C CA 1 +ATOM 6443 C C . PRO B 2 517 ? -17.495 10.125 -63.175 1.00 70.70 ? 517 PRO C C 1 +ATOM 6444 O O . PRO B 2 517 ? -16.558 9.327 -63.042 1.00 58.94 ? 517 PRO C O 1 +ATOM 6445 C CB . PRO B 2 517 ? -19.009 10.647 -61.227 1.00 72.76 ? 517 PRO C CB 1 +ATOM 6446 C CG . PRO B 2 517 ? -19.584 11.900 -60.690 1.00 71.06 ? 517 PRO C CG 1 +ATOM 6447 C CD . PRO B 2 517 ? -19.418 12.924 -61.772 1.00 72.12 ? 517 PRO C CD 1 +ATOM 6448 N N . HIS B 2 518 ? -18.247 10.168 -64.278 1.00 75.51 ? 518 HIS C N 1 +ATOM 6449 C CA . HIS B 2 518 ? -17.999 9.251 -65.385 1.00 61.48 ? 518 HIS C CA 1 +ATOM 6450 C C . HIS B 2 518 ? -16.693 9.583 -66.088 1.00 58.55 ? 518 HIS C C 1 +ATOM 6451 O O . HIS B 2 518 ? -15.924 8.682 -66.440 1.00 55.38 ? 518 HIS C O 1 +ATOM 6452 C CB . HIS B 2 518 ? -19.153 9.307 -66.386 1.00 51.19 ? 518 HIS C CB 1 +ATOM 6453 C CG . HIS B 2 518 ? -20.417 8.672 -65.899 1.00 45.81 ? 518 HIS C CG 1 +ATOM 6454 N ND1 . HIS B 2 518 ? -21.557 9.397 -65.624 1.00 50.06 ? 518 HIS C ND1 1 +ATOM 6455 C CD2 . HIS B 2 518 ? -20.727 7.379 -65.656 1.00 50.89 ? 518 HIS C CD2 1 +ATOM 6456 C CE1 . HIS B 2 518 ? -22.513 8.578 -65.225 1.00 51.09 ? 518 HIS C CE1 1 +ATOM 6457 N NE2 . HIS B 2 518 ? -22.034 7.347 -65.234 1.00 58.46 ? 518 HIS C NE2 1 +ATOM 6458 N N . LEU B 2 519 ? -16.428 10.874 -66.298 1.00 66.37 ? 519 LEU C N 1 +ATOM 6459 C CA . LEU B 2 519 ? -15.189 11.283 -66.952 1.00 75.81 ? 519 LEU C CA 1 +ATOM 6460 C C . LEU B 2 519 ? -13.969 10.848 -66.148 1.00 69.51 ? 519 LEU C C 1 +ATOM 6461 O O . LEU B 2 519 ? -12.934 10.480 -66.719 1.00 55.95 ? 519 LEU C O 1 +ATOM 6462 C CB . LEU B 2 519 ? -15.193 12.799 -67.164 1.00 69.70 ? 519 LEU C CB 1 +ATOM 6463 C CG . LEU B 2 519 ? -16.242 13.327 -68.149 1.00 64.14 ? 519 LEU C CG 1 +ATOM 6464 C CD1 . LEU B 2 519 ? -16.409 14.824 -68.002 1.00 71.84 ? 519 LEU C CD1 1 +ATOM 6465 C CD2 . LEU B 2 519 ? -15.876 12.977 -69.585 1.00 65.31 ? 519 LEU C CD2 1 +ATOM 6466 N N . GLU B 2 520 ? -14.071 10.889 -64.819 1.00 75.33 ? 520 GLU C N 1 +ATOM 6467 C CA . GLU B 2 520 ? -12.953 10.487 -63.975 1.00 75.26 ? 520 GLU C CA 1 +ATOM 6468 C C . GLU B 2 520 ? -12.861 8.970 -63.855 1.00 65.88 ? 520 GLU C C 1 +ATOM 6469 O O . GLU B 2 520 ? -11.753 8.423 -63.774 1.00 57.36 ? 520 GLU C O 1 +ATOM 6470 C CB . GLU B 2 520 ? -13.075 11.146 -62.601 1.00 75.91 ? 520 GLU C CB 1 +ATOM 6471 C CG . GLU B 2 520 ? -11.815 11.059 -61.756 1.00 71.29 ? 520 GLU C CG 1 +ATOM 6472 C CD . GLU B 2 520 ? -12.000 11.670 -60.383 1.00 79.28 ? 520 GLU C CD 1 +ATOM 6473 O OE1 . GLU B 2 520 ? -12.994 12.404 -60.192 1.00 87.59 ? 520 GLU C OE1 1 +ATOM 6474 O OE2 . GLU B 2 520 ? -11.140 11.440 -59.504 1.00 73.55 ? 520 GLU C OE2 1 +ATOM 6475 N N . ALA B 2 521 ? -14.010 8.284 -63.851 1.00 69.52 ? 521 ALA C N 1 +ATOM 6476 C CA . ALA B 2 521 ? -14.016 6.825 -63.832 1.00 64.83 ? 521 ALA C CA 1 +ATOM 6477 C C . ALA B 2 521 ? -13.320 6.250 -65.057 1.00 53.90 ? 521 ALA C C 1 +ATOM 6478 O O . ALA B 2 521 ? -12.802 5.130 -65.006 1.00 48.59 ? 521 ALA C O 1 +ATOM 6479 C CB . ALA B 2 521 ? -15.454 6.310 -63.747 1.00 59.56 ? 521 ALA C CB 1 +ATOM 6480 N N . LEU B 2 522 ? -13.299 7.002 -66.160 1.00 57.47 ? 522 LEU C N 1 +ATOM 6481 C CA . LEU B 2 522 ? -12.611 6.544 -67.361 1.00 57.16 ? 522 LEU C CA 1 +ATOM 6482 C C . LEU B 2 522 ? -11.149 6.235 -67.067 1.00 61.40 ? 522 LEU C C 1 +ATOM 6483 O O . LEU B 2 522 ? -10.604 5.244 -67.567 1.00 57.82 ? 522 LEU C O 1 +ATOM 6484 C CB . LEU B 2 522 ? -12.729 7.598 -68.459 1.00 52.41 ? 522 LEU C CB 1 +ATOM 6485 C CG . LEU B 2 522 ? -13.479 7.212 -69.731 1.00 49.05 ? 522 LEU C CG 1 +ATOM 6486 C CD1 . LEU B 2 522 ? -14.640 6.294 -69.425 1.00 48.77 ? 522 LEU C CD1 1 +ATOM 6487 C CD2 . LEU B 2 522 ? -13.987 8.471 -70.389 1.00 58.34 ? 522 LEU C CD2 1 +ATOM 6488 N N . ASP B 2 523 ? -10.494 7.077 -66.260 1.00 67.25 ? 523 ASP C N 1 +ATOM 6489 C CA . ASP B 2 523 ? -9.121 6.792 -65.858 1.00 63.65 ? 523 ASP C CA 1 +ATOM 6490 C C . ASP B 2 523 ? -9.066 5.602 -64.916 1.00 57.00 ? 523 ASP C C 1 +ATOM 6491 O O . ASP B 2 523 ? -8.072 4.867 -64.897 1.00 55.90 ? 523 ASP C O 1 +ATOM 6492 C CB . ASP B 2 523 ? -8.484 8.010 -65.184 1.00 65.85 ? 523 ASP C CB 1 +ATOM 6493 C CG . ASP B 2 523 ? -8.389 9.212 -66.104 1.00 68.81 ? 523 ASP C CG 1 +ATOM 6494 O OD1 . ASP B 2 523 ? -9.380 9.967 -66.194 1.00 63.11 ? 523 ASP C OD1 1 +ATOM 6495 O OD2 . ASP B 2 523 ? -7.335 9.390 -66.753 1.00 70.91 ? 523 ASP C OD2 1 +ATOM 6496 N N . ARG B 2 524 ? -10.112 5.417 -64.110 1.00 58.94 ? 524 ARG C N 1 +ATOM 6497 C CA . ARG B 2 524 ? -10.137 4.299 -63.178 1.00 62.70 ? 524 ARG C CA 1 +ATOM 6498 C C . ARG B 2 524 ? -10.315 2.972 -63.910 1.00 63.62 ? 524 ARG C C 1 +ATOM 6499 O O . ARG B 2 524 ? -9.586 2.008 -63.646 1.00 61.61 ? 524 ARG C O 1 +ATOM 6500 C CB . ARG B 2 524 ? -11.249 4.513 -62.151 1.00 52.18 ? 524 ARG C CB 1 +ATOM 6501 C CG . ARG B 2 524 ? -11.417 3.367 -61.185 1.00 50.81 ? 524 ARG C CG 1 +ATOM 6502 C CD . ARG B 2 524 ? -12.576 3.601 -60.252 1.00 50.97 ? 524 ARG C CD 1 +ATOM 6503 N NE . ARG B 2 524 ? -13.800 3.909 -60.984 1.00 60.09 ? 524 ARG C NE 1 +ATOM 6504 C CZ . ARG B 2 524 ? -14.994 4.061 -60.417 1.00 70.56 ? 524 ARG C CZ 1 +ATOM 6505 N NH1 . ARG B 2 524 ? -15.132 3.925 -59.104 1.00 74.59 ? 524 ARG C NH1 1 +ATOM 6506 N NH2 . ARG B 2 524 ? -16.054 4.340 -61.166 1.00 66.53 ? 524 ARG C NH2 1 +ATOM 6507 N N . ARG B 2 525 ? -11.256 2.909 -64.859 1.00 59.78 ? 525 ARG C N 1 +ATOM 6508 C CA . ARG B 2 525 ? -11.425 1.684 -65.632 1.00 50.63 ? 525 ARG C CA 1 +ATOM 6509 C C . ARG B 2 525 ? -10.228 1.428 -66.537 1.00 51.72 ? 525 ARG C C 1 +ATOM 6510 O O . ARG B 2 525 ? -9.884 0.269 -66.790 1.00 54.71 ? 525 ARG C O 1 +ATOM 6511 C CB . ARG B 2 525 ? -12.710 1.748 -66.462 1.00 49.48 ? 525 ARG C CB 1 +ATOM 6512 C CG . ARG B 2 525 ? -13.996 1.589 -65.664 1.00 49.82 ? 525 ARG C CG 1 +ATOM 6513 C CD . ARG B 2 525 ? -14.819 2.871 -65.707 1.00 51.58 ? 525 ARG C CD 1 +ATOM 6514 N NE . ARG B 2 525 ? -16.022 2.814 -64.879 1.00 54.48 ? 525 ARG C NE 1 +ATOM 6515 C CZ . ARG B 2 525 ? -17.252 2.651 -65.352 1.00 49.65 ? 525 ARG C CZ 1 +ATOM 6516 N NH1 . ARG B 2 525 ? -17.450 2.528 -66.654 1.00 55.49 ? 525 ARG C NH1 1 +ATOM 6517 N NH2 . ARG B 2 525 ? -18.285 2.618 -64.524 1.00 51.16 ? 525 ARG C NH2 1 +ATOM 6518 N N . LEU B 2 526 ? -9.567 2.486 -67.010 1.00 52.98 ? 526 LEU C N 1 +ATOM 6519 C CA . LEU B 2 526 ? -8.436 2.298 -67.913 1.00 54.85 ? 526 LEU C CA 1 +ATOM 6520 C C . LEU B 2 526 ? -7.254 1.658 -67.199 1.00 59.95 ? 526 LEU C C 1 +ATOM 6521 O O . LEU B 2 526 ? -6.607 0.754 -67.743 1.00 59.90 ? 526 LEU C O 1 +ATOM 6522 C CB . LEU B 2 526 ? -8.028 3.633 -68.535 1.00 52.92 ? 526 LEU C CB 1 +ATOM 6523 C CG . LEU B 2 526 ? -6.731 3.628 -69.348 1.00 60.55 ? 526 LEU C CG 1 +ATOM 6524 C CD1 . LEU B 2 526 ? -6.781 2.613 -70.483 1.00 59.73 ? 526 LEU C CD1 1 +ATOM 6525 C CD2 . LEU B 2 526 ? -6.452 5.018 -69.884 1.00 64.52 ? 526 LEU C CD2 1 +ATOM 6526 N N . ARG B 2 527 ? -6.957 2.104 -65.980 1.00 62.48 ? 527 ARG C N 1 +ATOM 6527 C CA . ARG B 2 527 ? -5.807 1.553 -65.278 1.00 64.12 ? 527 ARG C CA 1 +ATOM 6528 C C . ARG B 2 527 ? -6.032 0.098 -64.900 1.00 68.36 ? 527 ARG C C 1 +ATOM 6529 O O . ARG B 2 527 ? -5.068 -0.672 -64.813 1.00 71.37 ? 527 ARG C O 1 +ATOM 6530 C CB . ARG B 2 527 ? -5.499 2.401 -64.046 1.00 68.04 ? 527 ARG C CB 1 +ATOM 6531 C CG . ARG B 2 527 ? -6.576 2.384 -62.983 1.00 72.97 ? 527 ARG C CG 1 +ATOM 6532 C CD . ARG B 2 527 ? -5.952 2.430 -61.603 1.00 91.40 ? 527 ARG C CD 1 +ATOM 6533 N NE . ARG B 2 527 ? -6.925 2.739 -60.560 1.00 94.39 ? 527 ARG C NE 1 +ATOM 6534 C CZ . ARG B 2 527 ? -7.261 3.974 -60.199 1.00 87.61 ? 527 ARG C CZ 1 +ATOM 6535 N NH1 . ARG B 2 527 ? -6.710 5.020 -60.808 1.00 69.55 ? 527 ARG C NH1 1 +ATOM 6536 N NH2 . ARG B 2 527 ? -8.153 4.165 -59.234 1.00 83.26 ? 527 ARG C NH2 1 +ATOM 6537 N N . LEU B 2 528 ? -7.291 -0.315 -64.741 1.00 69.71 ? 528 LEU C N 1 +ATOM 6538 C CA . LEU B 2 528 ? -7.559 -1.724 -64.477 1.00 70.11 ? 528 LEU C CA 1 +ATOM 6539 C C . LEU B 2 528 ? -7.326 -2.563 -65.728 1.00 65.63 ? 528 LEU C C 1 +ATOM 6540 O O . LEU B 2 528 ? -6.752 -3.654 -65.648 1.00 65.99 ? 528 LEU C O 1 +ATOM 6541 C CB . LEU B 2 528 ? -8.986 -1.898 -63.957 1.00 62.82 ? 528 LEU C CB 1 +ATOM 6542 C CG . LEU B 2 528 ? -9.309 -1.120 -62.676 1.00 56.66 ? 528 LEU C CG 1 +ATOM 6543 C CD1 . LEU B 2 528 ? -10.700 -1.479 -62.149 1.00 49.77 ? 528 LEU C CD1 1 +ATOM 6544 C CD2 . LEU B 2 528 ? -8.235 -1.305 -61.609 1.00 55.11 ? 528 LEU C CD2 1 +ATOM 6545 N N . VAL B 2 529 ? -7.739 -2.057 -66.895 1.00 61.23 ? 529 VAL C N 1 +ATOM 6546 C CA . VAL B 2 529 ? -7.408 -2.725 -68.153 1.00 62.67 ? 529 VAL C CA 1 +ATOM 6547 C C . VAL B 2 529 ? -5.902 -2.767 -68.337 1.00 69.21 ? 529 VAL C C 1 +ATOM 6548 O O . VAL B 2 529 ? -5.337 -3.784 -68.759 1.00 70.10 ? 529 VAL C O 1 +ATOM 6549 C CB . VAL B 2 529 ? -8.089 -2.023 -69.342 1.00 56.68 ? 529 VAL C CB 1 +ATOM 6550 C CG1 . VAL B 2 529 ? -7.542 -2.563 -70.662 1.00 49.91 ? 529 VAL C CG1 1 +ATOM 6551 C CG2 . VAL B 2 529 ? -9.584 -2.206 -69.271 1.00 54.54 ? 529 VAL C CG2 1 +ATOM 6552 N N . LEU B 2 530 ? -5.232 -1.653 -68.039 1.00 68.62 ? 530 LEU C N 1 +ATOM 6553 C CA . LEU B 2 530 ? -3.782 -1.617 -68.144 1.00 70.24 ? 530 LEU C CA 1 +ATOM 6554 C C . LEU B 2 530 ? -3.134 -2.606 -67.184 1.00 74.11 ? 530 LEU C C 1 +ATOM 6555 O O . LEU B 2 530 ? -2.110 -3.216 -67.517 1.00 71.83 ? 530 LEU C O 1 +ATOM 6556 C CB . LEU B 2 530 ? -3.284 -0.197 -67.881 1.00 61.42 ? 530 LEU C CB 1 +ATOM 6557 C CG . LEU B 2 530 ? -2.143 0.283 -68.777 1.00 70.56 ? 530 LEU C CG 1 +ATOM 6558 C CD1 . LEU B 2 530 ? -2.451 0.013 -70.241 1.00 67.05 ? 530 LEU C CD1 1 +ATOM 6559 C CD2 . LEU B 2 530 ? -1.889 1.760 -68.548 1.00 74.01 ? 530 LEU C CD2 1 +ATOM 6560 N N . LYS B 2 531 ? -3.728 -2.798 -66.005 1.00 69.14 ? 531 LYS C N 1 +ATOM 6561 C CA . LYS B 2 531 ? -3.155 -3.716 -65.027 1.00 73.07 ? 531 LYS C CA 1 +ATOM 6562 C C . LYS B 2 531 ? -3.412 -5.173 -65.395 1.00 76.33 ? 531 LYS C C 1 +ATOM 6563 O O . LYS B 2 531 ? -2.545 -6.027 -65.180 1.00 81.07 ? 531 LYS C O 1 +ATOM 6564 C CB . LYS B 2 531 ? -3.706 -3.408 -63.636 1.00 78.07 ? 531 LYS C CB 1 +ATOM 6565 C CG . LYS B 2 531 ? -3.038 -4.194 -62.524 1.00 90.92 ? 531 LYS C CG 1 +ATOM 6566 C CD . LYS B 2 531 ? -1.561 -3.830 -62.415 1.00 88.18 ? 531 LYS C CD 1 +ATOM 6567 C CE . LYS B 2 531 ? -1.363 -2.443 -61.816 1.00 74.34 ? 531 LYS C CE 1 +ATOM 6568 N NZ . LYS B 2 531 ? 0.080 -2.097 -61.698 1.00 67.11 ? 531 LYS C NZ 1 +ATOM 6569 N N . VAL B 2 532 ? -4.590 -5.476 -65.950 1.00 75.48 ? 532 VAL C N 1 +ATOM 6570 C CA . VAL B 2 532 ? -4.880 -6.841 -66.389 1.00 71.81 ? 532 VAL C CA 1 +ATOM 6571 C C . VAL B 2 532 ? -3.913 -7.272 -67.485 1.00 71.22 ? 532 VAL C C 1 +ATOM 6572 O O . VAL B 2 532 ? -3.520 -8.444 -67.555 1.00 72.95 ? 532 VAL C O 1 +ATOM 6573 C CB . VAL B 2 532 ? -6.354 -6.957 -66.838 1.00 60.74 ? 532 VAL C CB 1 +ATOM 6574 C CG1 . VAL B 2 532 ? -6.591 -8.255 -67.582 1.00 64.38 ? 532 VAL C CG1 1 +ATOM 6575 C CG2 . VAL B 2 532 ? -7.278 -6.888 -65.637 1.00 50.83 ? 532 VAL C CG2 1 +ATOM 6576 N N . LEU B 2 533 ? -3.505 -6.338 -68.347 1.00 66.78 ? 533 LEU C N 1 +ATOM 6577 C CA . LEU B 2 533 ? -2.476 -6.643 -69.335 1.00 70.49 ? 533 LEU C CA 1 +ATOM 6578 C C . LEU B 2 533 ? -1.126 -6.880 -68.675 1.00 81.55 ? 533 LEU C C 1 +ATOM 6579 O O . LEU B 2 533 ? -0.332 -7.697 -69.157 1.00 83.53 ? 533 LEU C O 1 +ATOM 6580 C CB . LEU B 2 533 ? -2.382 -5.516 -70.359 1.00 68.03 ? 533 LEU C CB 1 +ATOM 6581 C CG . LEU B 2 533 ? -3.676 -5.267 -71.123 1.00 65.82 ? 533 LEU C CG 1 +ATOM 6582 C CD1 . LEU B 2 533 ? -3.491 -4.173 -72.153 1.00 66.59 ? 533 LEU C CD1 1 +ATOM 6583 C CD2 . LEU B 2 533 ? -4.139 -6.549 -71.780 1.00 54.88 ? 533 LEU C CD2 1 +ATOM 6584 N N . SER B 2 534 ? -0.847 -6.170 -67.587 1.00 84.01 ? 534 SER C N 1 +ATOM 6585 C CA . SER B 2 534 ? 0.421 -6.327 -66.886 1.00 87.42 ? 534 SER C CA 1 +ATOM 6586 C C . SER B 2 534 ? 0.446 -7.617 -66.069 1.00 89.75 ? 534 SER C C 1 +ATOM 6587 O O . SER B 2 534 ? 1.424 -8.374 -66.116 1.00 84.86 ? 534 SER C O 1 +ATOM 6588 C CB . SER B 2 534 ? 0.654 -5.113 -65.985 1.00 87.02 ? 534 SER C CB 1 +ATOM 6589 O OG . SER B 2 534 ? 0.574 -3.907 -66.731 1.00 78.59 ? 534 SER C OG 1 +ATOM 6590 N N . ASP B 2 535 ? -0.633 -7.882 -65.321 1.00 94.03 ? 535 ASP C N 1 +ATOM 6591 C CA . ASP B 2 535 ? -0.732 -9.090 -64.504 1.00 95.02 ? 535 ASP C CA 1 +ATOM 6592 C C . ASP B 2 535 ? -0.732 -10.363 -65.336 1.00 92.23 ? 535 ASP C C 1 +ATOM 6593 O O . ASP B 2 535 ? -0.460 -11.441 -64.796 1.00 95.14 ? 535 ASP C O 1 +ATOM 6594 C CB . ASP B 2 535 ? -2.000 -9.058 -63.645 1.00 86.45 ? 535 ASP C CB 1 +ATOM 6595 C CG . ASP B 2 535 ? -1.983 -7.940 -62.619 1.00 95.33 ? 535 ASP C CG 1 +ATOM 6596 O OD1 . ASP B 2 535 ? -0.884 -7.584 -62.139 1.00 90.90 ? 535 ASP C OD1 1 +ATOM 6597 O OD2 . ASP B 2 535 ? -3.073 -7.435 -62.275 1.00 98.05 ? 535 ASP C OD2 1 +ATOM 6598 N N . CYS B 2 536 ? -1.042 -10.268 -66.626 1.00 90.59 ? 536 CYS C N 1 +ATOM 6599 C CA . CYS B 2 536 ? -1.082 -11.444 -67.480 1.00 95.36 ? 536 CYS C CA 1 +ATOM 6600 C C . CYS B 2 536 ? 0.163 -11.593 -68.335 1.00 93.12 ? 536 CYS C C 1 +ATOM 6601 O O . CYS B 2 536 ? 0.572 -12.721 -68.631 1.00 96.07 ? 536 CYS C O 1 +ATOM 6602 C CB . CYS B 2 536 ? -2.313 -11.400 -68.392 1.00 85.70 ? 536 CYS C CB 1 +ATOM 6603 S SG . CYS B 2 536 ? -2.831 -13.047 -68.872 1.00 129.41 ? 536 CYS C SG 1 +ATOM 6604 N N . VAL B 2 537 ? 0.782 -10.482 -68.736 1.00 92.66 ? 537 VAL C N 1 +ATOM 6605 C CA . VAL B 2 537 ? 2.020 -10.579 -69.489 1.00 94.51 ? 537 VAL C CA 1 +ATOM 6606 C C . VAL B 2 537 ? 3.156 -11.132 -68.636 1.00 98.70 ? 537 VAL C C 1 +ATOM 6607 O O . VAL B 2 537 ? 4.167 -11.584 -69.183 1.00 95.23 ? 537 VAL C O 1 +ATOM 6608 C CB . VAL B 2 537 ? 2.391 -9.210 -70.085 1.00 96.12 ? 537 VAL C CB 1 +ATOM 6609 C CG1 . VAL B 2 537 ? 3.007 -8.301 -69.022 1.00 100.25 ? 537 VAL C CG1 1 +ATOM 6610 C CG2 . VAL B 2 537 ? 3.319 -9.399 -71.265 1.00 90.15 ? 537 VAL C CG2 1 +ATOM 6611 N N . GLU B 2 538 ? 3.022 -11.120 -67.308 1.00 98.38 ? 538 GLU C N 1 +ATOM 6612 C CA . GLU B 2 538 ? 4.005 -11.782 -66.460 1.00 98.59 ? 538 GLU C CA 1 +ATOM 6613 C C . GLU B 2 538 ? 3.776 -13.283 -66.365 1.00 98.38 ? 538 GLU C C 1 +ATOM 6614 O O . GLU B 2 538 ? 4.668 -14.000 -65.897 1.00 97.57 ? 538 GLU C O 1 +ATOM 6615 C CB . GLU B 2 538 ? 3.997 -11.195 -65.049 1.00 98.10 ? 538 GLU C CB 1 +ATOM 6616 C CG . GLU B 2 538 ? 2.783 -11.592 -64.234 1.00 109.19 ? 538 GLU C CG 1 +ATOM 6617 C CD . GLU B 2 538 ? 2.860 -11.119 -62.794 1.00 121.13 ? 538 GLU C CD 1 +ATOM 6618 O OE1 . GLU B 2 538 ? 2.792 -11.975 -61.885 1.00 121.14 ? 538 GLU C OE1 1 +ATOM 6619 O OE2 . GLU B 2 538 ? 3.003 -9.896 -62.574 1.00 122.22 ? 538 GLU C OE2 1 +ATOM 6620 N N . LYS B 2 539 ? 2.609 -13.770 -66.797 1.00 98.61 ? 539 LYS C N 1 +ATOM 6621 C CA . LYS B 2 539 ? 2.294 -15.190 -66.762 1.00 94.92 ? 539 LYS C CA 1 +ATOM 6622 C C . LYS B 2 539 ? 2.315 -15.844 -68.133 1.00 87.21 ? 539 LYS C C 1 +ATOM 6623 O O . LYS B 2 539 ? 2.400 -17.073 -68.208 1.00 95.64 ? 539 LYS C O 1 +ATOM 6624 C CB . LYS B 2 539 ? 0.912 -15.413 -66.124 1.00 94.76 ? 539 LYS C CB 1 +ATOM 6625 C CG . LYS B 2 539 ? 0.852 -15.016 -64.651 1.00 99.68 ? 539 LYS C CG 1 +ATOM 6626 C CD . LYS B 2 539 ? -0.509 -15.281 -64.021 1.00 96.18 ? 539 LYS C CD 1 +ATOM 6627 C CE . LYS B 2 539 ? -0.518 -14.842 -62.558 1.00 80.66 ? 539 LYS C CE 1 +ATOM 6628 N NZ . LYS B 2 539 ? -1.852 -15.017 -61.918 1.00 72.40 ? 539 LYS C NZ 1 +ATOM 6629 N N . ASP B 2 540 ? 2.264 -15.060 -69.209 1.00 78.62 ? 540 ASP C N 1 +ATOM 6630 C CA . ASP B 2 540 ? 2.401 -15.579 -70.559 1.00 78.28 ? 540 ASP C CA 1 +ATOM 6631 C C . ASP B 2 540 ? 3.527 -14.919 -71.344 1.00 80.23 ? 540 ASP C C 1 +ATOM 6632 O O . ASP B 2 540 ? 3.908 -15.443 -72.398 1.00 71.01 ? 540 ASP C O 1 +ATOM 6633 C CB . ASP B 2 540 ? 1.078 -15.433 -71.333 1.00 92.83 ? 540 ASP C CB 1 +ATOM 6634 C CG . ASP B 2 540 ? 0.034 -16.483 -70.934 1.00 91.41 ? 540 ASP C CG 1 +ATOM 6635 O OD1 . ASP B 2 540 ? 0.424 -17.629 -70.622 1.00 86.46 ? 540 ASP C OD1 1 +ATOM 6636 O OD2 . ASP B 2 540 ? -1.178 -16.166 -70.941 1.00 81.69 ? 540 ASP C OD2 1 +ATOM 6637 N N . GLY B 2 541 ? 4.075 -13.807 -70.862 1.00 85.16 ? 541 GLY C N 1 +ATOM 6638 C CA . GLY B 2 541 ? 5.191 -13.143 -71.506 1.00 89.90 ? 541 GLY C CA 1 +ATOM 6639 C C . GLY B 2 541 ? 4.766 -12.257 -72.665 1.00 91.79 ? 541 GLY C C 1 +ATOM 6640 O O . GLY B 2 541 ? 3.713 -12.432 -73.275 1.00 91.51 ? 541 GLY C O 1 +ATOM 6641 N N . PHE B 2 542 ? 5.615 -11.275 -72.966 1.00 89.66 ? 542 PHE C N 1 +ATOM 6642 C CA . PHE B 2 542 ? 5.417 -10.456 -74.155 1.00 87.86 ? 542 PHE C CA 1 +ATOM 6643 C C . PHE B 2 542 ? 5.612 -11.310 -75.406 1.00 89.19 ? 542 PHE C C 1 +ATOM 6644 O O . PHE B 2 542 ? 5.923 -12.504 -75.338 1.00 94.88 ? 542 PHE C O 1 +ATOM 6645 C CB . PHE B 2 542 ? 6.371 -9.262 -74.165 1.00 98.36 ? 542 PHE C CB 1 +ATOM 6646 C CG . PHE B 2 542 ? 6.051 -8.210 -73.136 1.00 111.96 ? 542 PHE C CG 1 +ATOM 6647 C CD1 . PHE B 2 542 ? 6.496 -8.342 -71.827 1.00 118.17 ? 542 PHE C CD1 1 +ATOM 6648 C CD2 . PHE B 2 542 ? 5.323 -7.078 -73.482 1.00 98.51 ? 542 PHE C CD2 1 +ATOM 6649 C CE1 . PHE B 2 542 ? 6.206 -7.372 -70.877 1.00 115.82 ? 542 PHE C CE1 1 +ATOM 6650 C CE2 . PHE B 2 542 ? 5.031 -6.104 -72.537 1.00 99.02 ? 542 PHE C CE2 1 +ATOM 6651 C CZ . PHE B 2 542 ? 5.473 -6.252 -71.234 1.00 106.42 ? 542 PHE C CZ 1 +ATOM 6652 N N . SER B 2 543 ? 5.391 -10.692 -76.569 1.00 87.75 ? 543 SER C N 1 +ATOM 6653 C CA . SER B 2 543 ? 5.478 -11.363 -77.866 1.00 94.50 ? 543 SER C CA 1 +ATOM 6654 C C . SER B 2 543 ? 4.424 -12.462 -78.006 1.00 94.29 ? 543 SER C C 1 +ATOM 6655 O O . SER B 2 543 ? 3.950 -12.733 -79.114 1.00 99.02 ? 543 SER C O 1 +ATOM 6656 C CB . SER B 2 543 ? 6.883 -11.935 -78.094 1.00 97.69 ? 543 SER C CB 1 +ATOM 6657 O OG . SER B 2 543 ? 7.860 -10.907 -78.105 1.00 103.94 ? 543 SER C OG 1 +ATOM 6658 N N . ALA B 2 544 ? 4.047 -13.094 -76.893 1.00 94.41 ? 544 ALA C N 1 +ATOM 6659 C CA . ALA B 2 544 ? 2.939 -14.037 -76.831 1.00 93.73 ? 544 ALA C CA 1 +ATOM 6660 C C . ALA B 2 544 ? 1.667 -13.412 -76.274 1.00 82.47 ? 544 ALA C C 1 +ATOM 6661 O O . ALA B 2 544 ? 0.631 -14.083 -76.214 1.00 75.46 ? 544 ALA C O 1 +ATOM 6662 C CB . ALA B 2 544 ? 3.326 -15.252 -75.980 1.00 95.37 ? 544 ALA C CB 1 +ATOM 6663 N N . VAL B 2 545 ? 1.725 -12.149 -75.850 1.00 80.01 ? 545 VAL C N 1 +ATOM 6664 C CA . VAL B 2 545 ? 0.544 -11.390 -75.473 1.00 75.02 ? 545 VAL C CA 1 +ATOM 6665 C C . VAL B 2 545 ? 0.310 -10.212 -76.409 1.00 75.48 ? 545 VAL C C 1 +ATOM 6666 O O . VAL B 2 545 ? -0.829 -9.942 -76.803 1.00 73.15 ? 545 VAL C O 1 +ATOM 6667 C CB . VAL B 2 545 ? 0.637 -10.914 -74.006 1.00 74.21 ? 545 VAL C CB 1 +ATOM 6668 C CG1 . VAL B 2 545 ? -0.416 -9.863 -73.704 1.00 63.62 ? 545 VAL C CG1 1 +ATOM 6669 C CG2 . VAL B 2 545 ? 0.482 -12.097 -73.062 1.00 84.51 ? 545 VAL C CG2 1 +ATOM 6670 N N . VAL B 2 546 ? 1.374 -9.536 -76.828 1.00 81.61 ? 546 VAL C N 1 +ATOM 6671 C CA . VAL B 2 546 ? 1.284 -8.406 -77.744 1.00 78.39 ? 546 VAL C CA 1 +ATOM 6672 C C . VAL B 2 546 ? 1.749 -8.858 -79.119 1.00 76.49 ? 546 VAL C C 1 +ATOM 6673 O O . VAL B 2 546 ? 2.818 -9.467 -79.258 1.00 75.37 ? 546 VAL C O 1 +ATOM 6674 C CB . VAL B 2 546 ? 2.100 -7.201 -77.245 1.00 86.54 ? 546 VAL C CB 1 +ATOM 6675 C CG1 . VAL B 2 546 ? 1.353 -6.501 -76.129 1.00 76.82 ? 546 VAL C CG1 1 +ATOM 6676 C CG2 . VAL B 2 546 ? 3.482 -7.645 -76.752 1.00 92.61 ? 546 VAL C CG2 1 +ATOM 6677 N N . GLU B 2 547 ? 0.924 -8.607 -80.124 1.00 79.87 ? 547 GLU C N 1 +ATOM 6678 C CA . GLU B 2 547 ? 1.268 -8.913 -81.504 1.00 88.05 ? 547 GLU C CA 1 +ATOM 6679 C C . GLU B 2 547 ? 1.741 -7.645 -82.202 1.00 90.60 ? 547 GLU C C 1 +ATOM 6680 O O . GLU B 2 547 ? 1.067 -6.609 -82.155 1.00 79.58 ? 547 GLU C O 1 +ATOM 6681 C CB . GLU B 2 547 ? 0.097 -9.545 -82.248 1.00 82.93 ? 547 GLU C CB 1 +ATOM 6682 C CG . GLU B 2 547 ? -0.048 -11.022 -81.953 1.00 82.39 ? 547 GLU C CG 1 +ATOM 6683 C CD . GLU B 2 547 ? -0.903 -11.724 -82.977 1.00 88.14 ? 547 GLU C CD 1 +ATOM 6684 O OE1 . GLU B 2 547 ? -1.798 -11.064 -83.542 1.00 78.51 ? 547 GLU C OE1 1 +ATOM 6685 O OE2 . GLU B 2 547 ? -0.688 -12.933 -83.208 1.00 102.17 ? 547 GLU C OE2 1 +ATOM 6686 N N . ASN B 2 548 ? 2.934 -7.724 -82.784 1.00 93.06 ? 548 ASN C N 1 +ATOM 6687 C CA . ASN B 2 548 ? 3.531 -6.618 -83.519 1.00 84.42 ? 548 ASN C CA 1 +ATOM 6688 C C . ASN B 2 548 ? 2.616 -6.164 -84.652 1.00 83.50 ? 548 ASN C C 1 +ATOM 6689 O O . ASN B 2 548 ? 2.156 -6.981 -85.455 1.00 78.60 ? 548 ASN C O 1 +ATOM 6690 C CB . ASN B 2 548 ? 4.883 -7.064 -84.077 1.00 81.74 ? 548 ASN C CB 1 +ATOM 6691 C CG . ASN B 2 548 ? 5.886 -5.940 -84.155 1.00 83.83 ? 548 ASN C CG 1 +ATOM 6692 O OD1 . ASN B 2 548 ? 5.532 -4.768 -84.028 1.00 90.41 ? 548 ASN C OD1 1 +ATOM 6693 N ND2 . ASN B 2 548 ? 7.148 -6.290 -84.367 1.00 80.73 ? 548 ASN C ND2 1 +ATOM 6694 N N . ASP B 2 549 ? 2.360 -4.856 -84.734 1.00 81.70 ? 549 ASP C N 1 +ATOM 6695 C CA . ASP B 2 549 ? 1.599 -4.313 -85.853 1.00 76.46 ? 549 ASP C CA 1 +ATOM 6696 C C . ASP B 2 549 ? 2.456 -3.478 -86.785 1.00 82.51 ? 549 ASP C C 1 +ATOM 6697 O O . ASP B 2 549 ? 2.415 -3.676 -88.001 1.00 86.47 ? 549 ASP C O 1 +ATOM 6698 C CB . ASP B 2 549 ? 0.453 -3.427 -85.348 1.00 66.99 ? 549 ASP C CB 1 +ATOM 6699 C CG . ASP B 2 549 ? -0.234 -4.002 -84.160 1.00 70.06 ? 549 ASP C CG 1 +ATOM 6700 O OD1 . ASP B 2 549 ? -0.744 -5.131 -84.280 1.00 75.55 ? 549 ASP C OD1 1 +ATOM 6701 O OD2 . ASP B 2 549 ? -0.250 -3.330 -83.107 1.00 69.65 ? 549 ASP C OD2 1 +ATOM 6702 N N . LEU B 2 550 ? 3.252 -2.561 -86.247 1.00 86.80 ? 550 LEU C N 1 +ATOM 6703 C CA . LEU B 2 550 ? 4.132 -1.737 -87.066 1.00 88.40 ? 550 LEU C CA 1 +ATOM 6704 C C . LEU B 2 550 ? 5.424 -2.507 -87.300 1.00 92.85 ? 550 LEU C C 1 +ATOM 6705 O O . LEU B 2 550 ? 6.199 -2.725 -86.362 1.00 91.13 ? 550 LEU C O 1 +ATOM 6706 C CB . LEU B 2 550 ? 4.386 -0.381 -86.420 1.00 81.68 ? 550 LEU C CB 1 +ATOM 6707 C CG . LEU B 2 550 ? 3.462 0.711 -86.965 1.00 92.95 ? 550 LEU C CG 1 +ATOM 6708 C CD1 . LEU B 2 550 ? 3.865 2.059 -86.404 1.00 99.78 ? 550 LEU C CD1 1 +ATOM 6709 C CD2 . LEU B 2 550 ? 3.450 0.740 -88.501 1.00 84.28 ? 550 LEU C CD2 1 +ATOM 6710 N N . ASP B 2 551 ? 5.646 -2.922 -88.544 1.00 96.98 ? 551 ASP C N 1 +ATOM 6711 C CA . ASP B 2 551 ? 6.861 -3.627 -88.939 1.00 101.83 ? 551 ASP C CA 1 +ATOM 6712 C C . ASP B 2 551 ? 6.998 -4.930 -88.152 1.00 100.79 ? 551 ASP C C 1 +ATOM 6713 O O . ASP B 2 551 ? 6.000 -5.521 -87.728 1.00 93.79 ? 551 ASP C O 1 +ATOM 6714 C CB . ASP B 2 551 ? 8.104 -2.745 -88.740 1.00 107.19 ? 551 ASP C CB 1 +ATOM 6715 C CG . ASP B 2 551 ? 8.116 -1.528 -89.658 1.00 114.35 ? 551 ASP C CG 1 +ATOM 6716 O OD1 . ASP B 2 551 ? 7.418 -1.553 -90.694 1.00 113.07 ? 551 ASP C OD1 1 +ATOM 6717 O OD2 . ASP B 2 551 ? 8.831 -0.548 -89.347 1.00 115.10 ? 551 ASP C OD2 1 +ATOM 6718 N N . SER C 1 27 ? -67.368 -7.296 -143.108 1.00 50.02 ? 89 SER B N 1 +ATOM 6719 C CA . SER C 1 27 ? -66.539 -7.819 -142.025 1.00 52.60 ? 89 SER B CA 1 +ATOM 6720 C C . SER C 1 27 ? -65.611 -6.727 -141.483 1.00 51.61 ? 89 SER B C 1 +ATOM 6721 O O . SER C 1 27 ? -65.478 -5.657 -142.087 1.00 50.95 ? 89 SER B O 1 +ATOM 6722 C CB . SER C 1 27 ? -65.732 -9.040 -142.489 1.00 55.96 ? 89 SER B CB 1 +ATOM 6723 O OG . SER C 1 27 ? -66.573 -10.098 -142.928 1.00 42.25 ? 89 SER B OG 1 +ATOM 6724 N N . SER C 1 28 ? -65.003 -7.005 -140.326 1.00 48.73 ? 90 SER B N 1 +ATOM 6725 C CA . SER C 1 28 ? -64.091 -6.091 -139.640 1.00 50.70 ? 90 SER B CA 1 +ATOM 6726 C C . SER C 1 28 ? -64.775 -4.782 -139.268 1.00 49.91 ? 90 SER B C 1 +ATOM 6727 O O . SER C 1 28 ? -64.655 -3.777 -139.981 1.00 41.58 ? 90 SER B O 1 +ATOM 6728 C CB . SER C 1 28 ? -62.855 -5.797 -140.493 1.00 52.91 ? 90 SER B CB 1 +ATOM 6729 O OG . SER C 1 28 ? -62.058 -4.799 -139.879 1.00 53.36 ? 90 SER B OG 1 +ATOM 6730 N N . LYS C 1 29 ? -65.468 -4.781 -138.126 1.00 50.69 ? 91 LYS B N 1 +ATOM 6731 C CA . LYS C 1 29 ? -66.105 -3.567 -137.633 1.00 47.27 ? 91 LYS B CA 1 +ATOM 6732 C C . LYS C 1 29 ? -65.085 -2.533 -137.187 1.00 46.79 ? 91 LYS B C 1 +ATOM 6733 O O . LYS C 1 29 ? -65.414 -1.344 -137.127 1.00 44.46 ? 91 LYS B O 1 +ATOM 6734 C CB . LYS C 1 29 ? -67.047 -3.899 -136.474 1.00 41.98 ? 91 LYS B CB 1 +ATOM 6735 C CG . LYS C 1 29 ? -68.211 -4.804 -136.834 1.00 38.00 ? 91 LYS B CG 1 +ATOM 6736 C CD . LYS C 1 29 ? -69.043 -5.097 -135.598 1.00 38.00 ? 91 LYS B CD 1 +ATOM 6737 C CE . LYS C 1 29 ? -69.992 -6.258 -135.815 1.00 38.00 ? 91 LYS B CE 1 +ATOM 6738 N NZ . LYS C 1 29 ? -71.357 -5.971 -135.294 1.00 45.94 ? 91 LYS B NZ 1 +ATOM 6739 N N . LEU C 1 30 ? -63.857 -2.959 -136.883 1.00 50.25 ? 92 LEU B N 1 +ATOM 6740 C CA . LEU C 1 30 ? -62.832 -2.022 -136.438 1.00 50.67 ? 92 LEU B CA 1 +ATOM 6741 C C . LEU C 1 30 ? -62.423 -1.089 -137.572 1.00 52.75 ? 92 LEU B C 1 +ATOM 6742 O O . LEU C 1 30 ? -62.316 0.128 -137.379 1.00 52.12 ? 92 LEU B O 1 +ATOM 6743 C CB . LEU C 1 30 ? -61.628 -2.790 -135.886 1.00 43.67 ? 92 LEU B CB 1 +ATOM 6744 C CG . LEU C 1 30 ? -60.665 -2.038 -134.961 1.00 40.58 ? 92 LEU B CG 1 +ATOM 6745 C CD1 . LEU C 1 30 ? -59.566 -1.349 -135.745 1.00 61.03 ? 92 LEU B CD1 1 +ATOM 6746 C CD2 . LEU C 1 30 ? -61.416 -1.022 -134.136 1.00 41.17 ? 92 LEU B CD2 1 +ATOM 6747 N N . GLN C 1 31 ? -62.199 -1.638 -138.770 1.00 57.09 ? 93 GLN B N 1 +ATOM 6748 C CA . GLN C 1 31 ? -61.879 -0.789 -139.913 1.00 58.57 ? 93 GLN B CA 1 +ATOM 6749 C C . GLN C 1 31 ? -63.035 0.147 -140.230 1.00 52.69 ? 93 GLN B C 1 +ATOM 6750 O O . GLN C 1 31 ? -62.822 1.305 -140.607 1.00 50.41 ? 93 GLN B O 1 +ATOM 6751 C CB . GLN C 1 31 ? -61.540 -1.644 -141.133 1.00 58.09 ? 93 GLN B CB 1 +ATOM 6752 C CG . GLN C 1 31 ? -60.229 -2.391 -141.022 1.00 61.13 ? 93 GLN B CG 1 +ATOM 6753 C CD . GLN C 1 31 ? -59.875 -3.145 -142.289 1.00 59.43 ? 93 GLN B CD 1 +ATOM 6754 O OE1 . GLN C 1 31 ? -60.591 -3.086 -143.291 1.00 51.42 ? 93 GLN B OE1 1 +ATOM 6755 N NE2 . GLN C 1 31 ? -58.759 -3.860 -142.250 1.00 72.01 ? 93 GLN B NE2 1 +ATOM 6756 N N . ALA C 1 32 ? -64.268 -0.338 -140.060 1.00 47.95 ? 94 ALA B N 1 +ATOM 6757 C CA . ALA C 1 32 ? -65.437 0.494 -140.310 1.00 47.54 ? 94 ALA B CA 1 +ATOM 6758 C C . ALA C 1 32 ? -65.502 1.679 -139.355 1.00 50.01 ? 94 ALA B C 1 +ATOM 6759 O O . ALA C 1 32 ? -65.976 2.755 -139.738 1.00 51.65 ? 94 ALA B O 1 +ATOM 6760 C CB . ALA C 1 32 ? -66.705 -0.353 -140.201 1.00 46.14 ? 94 ALA B CB 1 +ATOM 6761 N N . LEU C 1 33 ? -65.015 1.514 -138.121 1.00 44.04 ? 95 LEU B N 1 +ATOM 6762 C CA . LEU C 1 33 ? -65.071 2.602 -137.148 1.00 41.61 ? 95 LEU B CA 1 +ATOM 6763 C C . LEU C 1 33 ? -64.201 3.775 -137.581 1.00 45.59 ? 95 LEU B C 1 +ATOM 6764 O O . LEU C 1 33 ? -64.652 4.925 -137.590 1.00 48.44 ? 95 LEU B O 1 +ATOM 6765 C CB . LEU C 1 33 ? -64.640 2.107 -135.767 1.00 46.01 ? 95 LEU B CB 1 +ATOM 6766 C CG . LEU C 1 33 ? -64.783 3.102 -134.606 1.00 38.00 ? 95 LEU B CG 1 +ATOM 6767 C CD1 . LEU C 1 33 ? -66.220 3.554 -134.454 1.00 38.00 ? 95 LEU B CD1 1 +ATOM 6768 C CD2 . LEU C 1 33 ? -64.254 2.532 -133.297 1.00 38.00 ? 95 LEU B CD2 1 +ATOM 6769 N N . PHE C 1 34 ? -62.937 3.511 -137.914 1.00 45.08 ? 96 PHE B N 1 +ATOM 6770 C CA . PHE C 1 34 ? -62.018 4.590 -138.248 1.00 42.80 ? 96 PHE B CA 1 +ATOM 6771 C C . PHE C 1 34 ? -62.227 5.133 -139.654 1.00 45.70 ? 96 PHE B C 1 +ATOM 6772 O O . PHE C 1 34 ? -61.749 6.233 -139.953 1.00 45.40 ? 96 PHE B O 1 +ATOM 6773 C CB . PHE C 1 34 ? -60.578 4.116 -138.061 1.00 40.00 ? 96 PHE B CB 1 +ATOM 6774 C CG . PHE C 1 34 ? -60.228 3.820 -136.627 1.00 42.39 ? 96 PHE B CG 1 +ATOM 6775 C CD1 . PHE C 1 34 ? -59.955 4.848 -135.738 1.00 38.00 ? 96 PHE B CD1 1 +ATOM 6776 C CD2 . PHE C 1 34 ? -60.218 2.516 -136.159 1.00 39.51 ? 96 PHE B CD2 1 +ATOM 6777 C CE1 . PHE C 1 34 ? -59.649 4.573 -134.424 1.00 38.00 ? 96 PHE B CE1 1 +ATOM 6778 C CE2 . PHE C 1 34 ? -59.919 2.239 -134.849 1.00 38.00 ? 96 PHE B CE2 1 +ATOM 6779 C CZ . PHE C 1 34 ? -59.633 3.266 -133.981 1.00 38.00 ? 96 PHE B CZ 1 +ATOM 6780 N N . ALA C 1 35 ? -62.943 4.407 -140.511 1.00 49.06 ? 97 ALA B N 1 +ATOM 6781 C CA . ALA C 1 35 ? -63.297 4.904 -141.832 1.00 48.93 ? 97 ALA B CA 1 +ATOM 6782 C C . ALA C 1 35 ? -64.621 5.657 -141.832 1.00 48.96 ? 97 ALA B C 1 +ATOM 6783 O O . ALA C 1 35 ? -65.067 6.114 -142.890 1.00 46.34 ? 97 ALA B O 1 +ATOM 6784 C CB . ALA C 1 35 ? -63.357 3.741 -142.828 1.00 49.14 ? 97 ALA B CB 1 +ATOM 6785 N N . HIS C 1 36 ? -65.226 5.833 -140.666 1.00 50.20 ? 98 HIS B N 1 +ATOM 6786 C CA . HIS C 1 36 ? -66.475 6.549 -140.504 1.00 49.06 ? 98 HIS B CA 1 +ATOM 6787 C C . HIS C 1 36 ? -66.215 8.054 -140.529 1.00 48.70 ? 98 HIS B C 1 +ATOM 6788 O O . HIS C 1 36 ? -65.174 8.514 -140.054 1.00 50.47 ? 98 HIS B O 1 +ATOM 6789 C CB . HIS C 1 36 ? -67.130 6.149 -139.186 1.00 51.23 ? 98 HIS B CB 1 +ATOM 6790 C CG . HIS C 1 36 ? -68.553 6.583 -139.052 1.00 55.36 ? 98 HIS B CG 1 +ATOM 6791 N ND1 . HIS C 1 36 ? -68.909 7.836 -138.599 1.00 57.88 ? 98 HIS B ND1 1 +ATOM 6792 C CD2 . HIS C 1 36 ? -69.711 5.921 -139.282 1.00 53.88 ? 98 HIS B CD2 1 +ATOM 6793 C CE1 . HIS C 1 36 ? -70.226 7.934 -138.577 1.00 59.93 ? 98 HIS B CE1 1 +ATOM 6794 N NE2 . HIS C 1 36 ? -70.737 6.786 -138.985 1.00 64.39 ? 98 HIS B NE2 1 +ATOM 6795 N N . PRO C 1 37 ? -67.151 8.837 -141.070 1.00 48.78 ? 99 PRO B N 1 +ATOM 6796 C CA . PRO C 1 37 ? -66.953 10.297 -141.138 1.00 48.69 ? 99 PRO B CA 1 +ATOM 6797 C C . PRO C 1 37 ? -66.626 10.955 -139.808 1.00 49.56 ? 99 PRO B C 1 +ATOM 6798 O O . PRO C 1 37 ? -66.000 12.022 -139.799 1.00 45.72 ? 99 PRO B O 1 +ATOM 6799 C CB . PRO C 1 37 ? -68.294 10.799 -141.690 1.00 52.89 ? 99 PRO B CB 1 +ATOM 6800 C CG . PRO C 1 37 ? -68.805 9.663 -142.502 1.00 60.83 ? 99 PRO B CG 1 +ATOM 6801 C CD . PRO C 1 37 ? -68.353 8.406 -141.804 1.00 55.62 ? 99 PRO B CD 1 +ATOM 6802 N N . LEU C 1 38 ? -67.041 10.367 -138.685 1.00 51.41 ? 100 LEU B N 1 +ATOM 6803 C CA . LEU C 1 38 ? -66.736 10.961 -137.387 1.00 54.66 ? 100 LEU B CA 1 +ATOM 6804 C C . LEU C 1 38 ? -65.239 10.957 -137.114 1.00 57.13 ? 100 LEU B C 1 +ATOM 6805 O O . LEU C 1 38 ? -64.678 11.957 -136.652 1.00 60.08 ? 100 LEU B O 1 +ATOM 6806 C CB . LEU C 1 38 ? -67.473 10.218 -136.277 1.00 50.78 ? 100 LEU B CB 1 +ATOM 6807 C CG . LEU C 1 38 ? -68.508 11.040 -135.518 1.00 46.65 ? 100 LEU B CG 1 +ATOM 6808 C CD1 . LEU C 1 38 ? -69.146 10.191 -134.438 1.00 43.65 ? 100 LEU B CD1 1 +ATOM 6809 C CD2 . LEU C 1 38 ? -67.870 12.294 -134.930 1.00 47.86 ? 100 LEU B CD2 1 +ATOM 6810 N N . TYR C 1 39 ? -64.581 9.831 -137.375 1.00 52.44 ? 101 TYR B N 1 +ATOM 6811 C CA . TYR C 1 39 ? -63.154 9.692 -137.115 1.00 51.79 ? 101 TYR B CA 1 +ATOM 6812 C C . TYR C 1 39 ? -62.305 10.214 -138.267 1.00 53.93 ? 101 TYR B C 1 +ATOM 6813 O O . TYR C 1 39 ? -61.232 9.668 -138.543 1.00 52.86 ? 101 TYR B O 1 +ATOM 6814 C CB . TYR C 1 39 ? -62.817 8.232 -136.856 1.00 47.67 ? 101 TYR B CB 1 +ATOM 6815 C CG . TYR C 1 39 ? -63.471 7.663 -135.628 1.00 44.69 ? 101 TYR B CG 1 +ATOM 6816 C CD1 . TYR C 1 39 ? -64.816 7.342 -135.621 1.00 41.91 ? 101 TYR B CD1 1 +ATOM 6817 C CD2 . TYR C 1 39 ? -62.737 7.433 -134.478 1.00 49.14 ? 101 TYR B CD2 1 +ATOM 6818 C CE1 . TYR C 1 39 ? -65.414 6.815 -134.505 1.00 42.58 ? 101 TYR B CE1 1 +ATOM 6819 C CE2 . TYR C 1 39 ? -63.326 6.903 -133.357 1.00 47.02 ? 101 TYR B CE2 1 +ATOM 6820 C CZ . TYR C 1 39 ? -64.665 6.591 -133.374 1.00 41.59 ? 101 TYR B CZ 1 +ATOM 6821 O OH . TYR C 1 39 ? -65.258 6.061 -132.253 1.00 38.00 ? 101 TYR B OH 1 +ATOM 6822 N N . ASN C 1 40 ? -62.768 11.268 -138.940 1.00 54.44 ? 102 ASN B N 1 +ATOM 6823 C CA . ASN C 1 40 ? -62.074 11.787 -140.112 1.00 49.81 ? 102 ASN B CA 1 +ATOM 6824 C C . ASN C 1 40 ? -62.285 13.289 -140.247 1.00 55.60 ? 102 ASN B C 1 +ATOM 6825 O O . ASN C 1 40 ? -61.530 13.966 -140.954 1.00 60.45 ? 102 ASN B O 1 +ATOM 6826 C CB . ASN C 1 40 ? -62.539 11.052 -141.371 1.00 48.82 ? 102 ASN B CB 1 +ATOM 6827 C CG . ASN C 1 40 ? -61.880 9.687 -141.532 1.00 51.99 ? 102 ASN B CG 1 +ATOM 6828 O OD1 . ASN C 1 40 ? -60.666 9.555 -141.376 1.00 54.28 ? 102 ASN B OD1 1 +ATOM 6829 N ND2 . ASN C 1 40 ? -62.679 8.666 -141.823 1.00 50.71 ? 102 ASN B ND2 1 +ATOM 6830 N N . VAL C 1 41 ? -63.310 13.818 -139.590 1.00 61.10 ? 103 VAL B N 1 +ATOM 6831 C CA . VAL C 1 41 ? -63.573 15.264 -139.658 1.00 68.36 ? 103 VAL B CA 1 +ATOM 6832 C C . VAL C 1 41 ? -62.422 16.019 -138.997 1.00 63.47 ? 103 VAL B C 1 +ATOM 6833 O O . VAL C 1 41 ? -61.878 15.545 -137.982 1.00 63.11 ? 103 VAL B O 1 +ATOM 6834 C CB . VAL C 1 41 ? -64.909 15.597 -138.991 1.00 65.30 ? 103 VAL B CB 1 +ATOM 6835 C CG1 . VAL C 1 41 ? -66.063 15.121 -139.861 1.00 62.41 ? 103 VAL B CG1 1 +ATOM 6836 C CG2 . VAL C 1 41 ? -64.984 14.968 -137.605 1.00 50.45 ? 103 VAL B CG2 1 +ATOM 6837 N N . PRO C 1 42 ? -62.015 17.177 -139.519 1.00 61.80 ? 104 PRO B N 1 +ATOM 6838 C CA . PRO C 1 42 ? -60.951 17.942 -138.858 1.00 69.62 ? 104 PRO B CA 1 +ATOM 6839 C C . PRO C 1 42 ? -61.389 18.399 -137.477 1.00 82.19 ? 104 PRO B C 1 +ATOM 6840 O O . PRO C 1 42 ? -62.566 18.676 -137.234 1.00 89.52 ? 104 PRO B O 1 +ATOM 6841 C CB . PRO C 1 42 ? -60.732 19.138 -139.794 1.00 59.85 ? 104 PRO B CB 1 +ATOM 6842 C CG . PRO C 1 42 ? -61.266 18.699 -141.106 1.00 64.00 ? 104 PRO B CG 1 +ATOM 6843 C CD . PRO C 1 42 ? -62.414 17.786 -140.796 1.00 62.13 ? 104 PRO B CD 1 +ATOM 6844 N N . GLU C 1 43 ? -60.429 18.468 -136.564 1.00 77.79 ? 105 GLU B N 1 +ATOM 6845 C CA . GLU C 1 43 ? -60.706 18.885 -135.200 1.00 82.33 ? 105 GLU B CA 1 +ATOM 6846 C C . GLU C 1 43 ? -60.488 20.386 -135.062 1.00 86.51 ? 105 GLU B C 1 +ATOM 6847 O O . GLU C 1 43 ? -59.494 20.923 -135.566 1.00 82.98 ? 105 GLU B O 1 +ATOM 6848 C CB . GLU C 1 43 ? -59.833 18.120 -134.207 1.00 85.10 ? 105 GLU B CB 1 +ATOM 6849 C CG . GLU C 1 43 ? -60.506 16.889 -133.617 1.00 85.20 ? 105 GLU B CG 1 +ATOM 6850 C CD . GLU C 1 43 ? -59.559 16.074 -132.758 1.00 83.82 ? 105 GLU B CD 1 +ATOM 6851 O OE1 . GLU C 1 43 ? -58.434 15.790 -133.225 1.00 83.41 ? 105 GLU B OE1 1 +ATOM 6852 O OE2 . GLU C 1 43 ? -59.935 15.729 -131.614 1.00 76.12 ? 105 GLU B OE2 1 +ATOM 6853 N N . GLU C 1 44 ? -61.436 21.064 -134.392 1.00 92.97 ? 106 GLU B N 1 +ATOM 6854 C CA . GLU C 1 44 ? -61.404 22.504 -134.173 1.00 96.02 ? 106 GLU B CA 1 +ATOM 6855 C C . GLU C 1 44 ? -61.041 22.817 -132.724 1.00 96.02 ? 106 GLU B C 1 +ATOM 6856 O O . GLU C 1 44 ? -61.469 22.103 -131.809 1.00 95.14 ? 106 GLU B O 1 +ATOM 6857 C CB . GLU C 1 44 ? -62.760 23.147 -134.500 1.00 100.02 ? 106 GLU B CB 1 +ATOM 6858 C CG . GLU C 1 44 ? -63.364 22.736 -135.844 1.00 103.48 ? 106 GLU B CG 1 +ATOM 6859 C CD . GLU C 1 44 ? -62.654 23.357 -137.041 1.00 106.10 ? 106 GLU B CD 1 +ATOM 6860 O OE1 . GLU C 1 44 ? -61.824 24.274 -136.847 1.00 100.77 ? 106 GLU B OE1 1 +ATOM 6861 O OE2 . GLU C 1 44 ? -62.922 22.918 -138.180 1.00 106.39 ? 106 GLU B OE2 1 +ATOM 6862 N N . PRO C 1 45 ? -60.251 23.876 -132.478 1.00 93.41 ? 107 PRO B N 1 +ATOM 6863 C CA . PRO C 1 45 ? -59.624 24.723 -133.504 1.00 91.70 ? 107 PRO B CA 1 +ATOM 6864 C C . PRO C 1 45 ? -58.430 24.037 -134.180 1.00 91.00 ? 107 PRO B C 1 +ATOM 6865 O O . PRO C 1 45 ? -57.831 23.150 -133.573 1.00 94.15 ? 107 PRO B O 1 +ATOM 6866 C CB . PRO C 1 45 ? -59.162 25.956 -132.710 1.00 84.76 ? 107 PRO B CB 1 +ATOM 6867 C CG . PRO C 1 45 ? -59.910 25.891 -131.403 1.00 85.19 ? 107 PRO B CG 1 +ATOM 6868 C CD . PRO C 1 45 ? -60.065 24.432 -131.129 1.00 88.95 ? 107 PRO B CD 1 +ATOM 6869 N N . PRO C 1 46 ? -58.093 24.432 -135.409 1.00 91.45 ? 108 PRO B N 1 +ATOM 6870 C CA . PRO C 1 46 ? -56.916 23.854 -136.069 1.00 85.98 ? 108 PRO B CA 1 +ATOM 6871 C C . PRO C 1 46 ? -55.627 24.332 -135.416 1.00 89.28 ? 108 PRO B C 1 +ATOM 6872 O O . PRO C 1 46 ? -55.599 25.319 -134.676 1.00 93.36 ? 108 PRO B O 1 +ATOM 6873 C CB . PRO C 1 46 ? -57.020 24.355 -137.515 1.00 87.34 ? 108 PRO B CB 1 +ATOM 6874 C CG . PRO C 1 46 ? -58.383 24.973 -137.650 1.00 85.00 ? 108 PRO B CG 1 +ATOM 6875 C CD . PRO C 1 46 ? -58.814 25.377 -136.277 1.00 88.52 ? 108 PRO B CD 1 +ATOM 6876 N N . LEU C 1 47 ? -54.539 23.626 -135.720 1.00 86.93 ? 109 LEU B N 1 +ATOM 6877 C CA . LEU C 1 47 ? -53.250 23.869 -135.081 1.00 92.12 ? 109 LEU B CA 1 +ATOM 6878 C C . LEU C 1 47 ? -52.377 24.737 -135.979 1.00 87.90 ? 109 LEU B C 1 +ATOM 6879 O O . LEU C 1 47 ? -52.088 24.367 -137.122 1.00 83.85 ? 109 LEU B O 1 +ATOM 6880 C CB . LEU C 1 47 ? -52.545 22.554 -134.744 1.00 91.82 ? 109 LEU B CB 1 +ATOM 6881 C CG . LEU C 1 47 ? -53.371 21.474 -134.035 1.00 89.29 ? 109 LEU B CG 1 +ATOM 6882 C CD1 . LEU C 1 47 ? -52.595 20.174 -133.985 1.00 79.10 ? 109 LEU B CD1 1 +ATOM 6883 C CD2 . LEU C 1 47 ? -53.776 21.906 -132.626 1.00 76.01 ? 109 LEU B CD2 1 +ATOM 6884 N N . LEU C 1 48 ? -51.956 25.888 -135.451 1.00 94.63 ? 110 LEU B N 1 +ATOM 6885 C CA . LEU C 1 48 ? -51.049 26.773 -136.171 1.00 92.32 ? 110 LEU B CA 1 +ATOM 6886 C C . LEU C 1 48 ? -49.619 26.241 -136.197 1.00 90.74 ? 110 LEU B C 1 +ATOM 6887 O O . LEU C 1 48 ? -48.841 26.635 -137.072 1.00 85.57 ? 110 LEU B O 1 +ATOM 6888 C CB . LEU C 1 48 ? -51.090 28.177 -135.557 1.00 86.50 ? 110 LEU B CB 1 +ATOM 6889 C CG . LEU C 1 48 ? -51.516 28.308 -134.087 1.00 90.73 ? 110 LEU B CG 1 +ATOM 6890 C CD1 . LEU C 1 48 ? -50.777 29.449 -133.404 1.00 84.88 ? 110 LEU B CD1 1 +ATOM 6891 C CD2 . LEU C 1 48 ? -53.029 28.503 -133.946 1.00 82.08 ? 110 LEU B CD2 1 +ATOM 6892 N N . GLY C 1 49 ? -49.257 25.365 -135.266 1.00 94.53 ? 111 GLY B N 1 +ATOM 6893 C CA . GLY C 1 49 ? -47.906 24.853 -135.158 1.00 92.94 ? 111 GLY B CA 1 +ATOM 6894 C C . GLY C 1 49 ? -47.076 25.638 -134.155 1.00 93.04 ? 111 GLY B C 1 +ATOM 6895 O O . GLY C 1 49 ? -47.495 26.660 -133.605 1.00 94.63 ? 111 GLY B O 1 +ATOM 6896 N N . ALA C 1 50 ? -45.862 25.133 -133.924 1.00 84.92 ? 112 ALA B N 1 +ATOM 6897 C CA . ALA C 1 50 ? -44.913 25.740 -132.996 1.00 87.33 ? 112 ALA B CA 1 +ATOM 6898 C C . ALA C 1 50 ? -45.473 25.819 -131.576 1.00 88.95 ? 112 ALA B C 1 +ATOM 6899 O O . ALA C 1 50 ? -44.999 25.113 -130.681 1.00 85.43 ? 112 ALA B O 1 +ATOM 6900 C CB . ALA C 1 50 ? -44.491 27.129 -133.489 1.00 80.25 ? 112 ALA B CB 1 +ATOM 6901 N N . GLU C 1 51 ? -46.481 26.667 -131.355 1.00 95.79 ? 113 GLU B N 1 +ATOM 6902 C CA . GLU C 1 51 ? -47.074 26.842 -130.032 1.00 94.67 ? 113 GLU B CA 1 +ATOM 6903 C C . GLU C 1 51 ? -48.129 25.789 -129.708 1.00 88.61 ? 113 GLU B C 1 +ATOM 6904 O O . GLU C 1 51 ? -48.628 25.758 -128.575 1.00 80.75 ? 113 GLU B O 1 +ATOM 6905 C CB . GLU C 1 51 ? -47.701 28.239 -129.911 1.00 98.13 ? 113 GLU B CB 1 +ATOM 6906 C CG . GLU C 1 51 ? -46.766 29.385 -130.282 1.00 96.82 ? 113 GLU B CG 1 +ATOM 6907 C CD . GLU C 1 51 ? -46.721 29.641 -131.783 1.00 110.59 ? 113 GLU B CD 1 +ATOM 6908 O OE1 . GLU C 1 51 ? -47.694 29.284 -132.485 1.00 107.82 ? 113 GLU B OE1 1 +ATOM 6909 O OE2 . GLU C 1 51 ? -45.707 30.190 -132.263 1.00 114.57 ? 113 GLU B OE2 1 +ATOM 6910 N N . ASP C 1 52 ? -48.468 24.923 -130.658 1.00 87.17 ? 114 ASP B N 1 +ATOM 6911 C CA . ASP C 1 52 ? -49.432 23.853 -130.445 1.00 80.80 ? 114 ASP B CA 1 +ATOM 6912 C C . ASP C 1 52 ? -48.765 22.487 -130.380 1.00 77.41 ? 114 ASP B C 1 +ATOM 6913 O O . ASP C 1 52 ? -49.460 21.467 -130.340 1.00 71.54 ? 114 ASP B O 1 +ATOM 6914 C CB . ASP C 1 52 ? -50.497 23.878 -131.544 1.00 87.00 ? 114 ASP B CB 1 +ATOM 6915 C CG . ASP C 1 52 ? -51.420 25.087 -131.440 1.00 89.38 ? 114 ASP B CG 1 +ATOM 6916 O OD1 . ASP C 1 52 ? -51.295 25.855 -130.461 1.00 91.30 ? 114 ASP B OD1 1 +ATOM 6917 O OD2 . ASP C 1 52 ? -52.274 25.270 -132.339 1.00 87.89 ? 114 ASP B OD2 1 +ATOM 6918 N N . SER C 1 53 ? -47.432 22.448 -130.354 1.00 81.25 ? 115 SER B N 1 +ATOM 6919 C CA . SER C 1 53 ? -46.649 21.232 -130.147 1.00 82.49 ? 115 SER B CA 1 +ATOM 6920 C C . SER C 1 53 ? -45.857 21.425 -128.858 1.00 72.26 ? 115 SER B C 1 +ATOM 6921 O O . SER C 1 53 ? -44.969 22.282 -128.799 1.00 72.27 ? 115 SER B O 1 +ATOM 6922 C CB . SER C 1 53 ? -45.721 20.965 -131.335 1.00 68.22 ? 115 SER B CB 1 +ATOM 6923 O OG . SER C 1 53 ? -46.406 20.327 -132.398 1.00 54.53 ? 115 SER B OG 1 +ATOM 6924 N N . LEU C 1 54 ? -46.180 20.640 -127.823 1.00 64.29 ? 116 LEU B N 1 +ATOM 6925 C CA . LEU C 1 54 ? -45.621 20.902 -126.497 1.00 67.77 ? 116 LEU B CA 1 +ATOM 6926 C C . LEU C 1 54 ? -44.108 20.782 -126.470 1.00 62.87 ? 116 LEU B C 1 +ATOM 6927 O O . LEU C 1 54 ? -43.467 21.353 -125.580 1.00 65.78 ? 116 LEU B O 1 +ATOM 6928 C CB . LEU C 1 54 ? -46.237 19.969 -125.444 1.00 72.06 ? 116 LEU B CB 1 +ATOM 6929 C CG . LEU C 1 54 ? -46.168 18.434 -125.493 1.00 61.27 ? 116 LEU B CG 1 +ATOM 6930 C CD1 . LEU C 1 54 ? -44.802 17.872 -125.123 1.00 56.12 ? 116 LEU B CD1 1 +ATOM 6931 C CD2 . LEU C 1 54 ? -47.215 17.871 -124.562 1.00 55.95 ? 116 LEU B CD2 1 +ATOM 6932 N N . LEU C 1 55 ? -43.527 20.042 -127.403 1.00 55.31 ? 117 LEU B N 1 +ATOM 6933 C CA . LEU C 1 55 ? -42.087 19.861 -127.473 1.00 53.92 ? 117 LEU B CA 1 +ATOM 6934 C C . LEU C 1 55 ? -41.554 20.684 -128.635 1.00 54.44 ? 117 LEU B C 1 +ATOM 6935 O O . LEU C 1 55 ? -42.012 20.527 -129.773 1.00 60.70 ? 117 LEU B O 1 +ATOM 6936 C CB . LEU C 1 55 ? -41.735 18.385 -127.637 1.00 53.54 ? 117 LEU B CB 1 +ATOM 6937 C CG . LEU C 1 55 ? -40.714 17.839 -126.643 1.00 42.68 ? 117 LEU B CG 1 +ATOM 6938 C CD1 . LEU C 1 55 ? -41.214 18.001 -125.224 1.00 42.35 ? 117 LEU B CD1 1 +ATOM 6939 C CD2 . LEU C 1 55 ? -40.428 16.386 -126.951 1.00 39.38 ? 117 LEU B CD2 1 +ATOM 6940 N N . ALA C 1 56 ? -40.606 21.569 -128.347 1.00 49.42 ? 118 ALA B N 1 +ATOM 6941 C CA . ALA C 1 56 ? -39.923 22.302 -129.401 1.00 54.02 ? 118 ALA B CA 1 +ATOM 6942 C C . ALA C 1 56 ? -38.862 21.400 -130.017 1.00 58.45 ? 118 ALA B C 1 +ATOM 6943 O O . ALA C 1 56 ? -38.072 20.781 -129.299 1.00 62.71 ? 118 ALA B O 1 +ATOM 6944 C CB . ALA C 1 56 ? -39.296 23.583 -128.853 1.00 57.52 ? 118 ALA B CB 1 +ATOM 6945 N N . SER C 1 57 ? -38.851 21.324 -131.349 1.00 60.31 ? 119 SER B N 1 +ATOM 6946 C CA . SER C 1 57 ? -38.017 20.346 -132.040 1.00 57.80 ? 119 SER B CA 1 +ATOM 6947 C C . SER C 1 57 ? -36.538 20.543 -131.719 1.00 60.35 ? 119 SER B C 1 +ATOM 6948 O O . SER C 1 57 ? -35.863 19.619 -131.252 1.00 57.22 ? 119 SER B O 1 +ATOM 6949 C CB . SER C 1 57 ? -38.270 20.430 -133.546 1.00 64.16 ? 119 SER B CB 1 +ATOM 6950 O OG . SER C 1 57 ? -38.263 21.778 -133.980 1.00 74.26 ? 119 SER B OG 1 +ATOM 6951 N N . GLN C 1 58 ? -36.013 21.747 -131.955 1.00 63.07 ? 120 GLN B N 1 +ATOM 6952 C CA . GLN C 1 58 ? -34.579 21.954 -131.781 1.00 65.71 ? 120 GLN B CA 1 +ATOM 6953 C C . GLN C 1 58 ? -34.172 21.782 -130.324 1.00 63.39 ? 120 GLN B C 1 +ATOM 6954 O O . GLN C 1 58 ? -33.108 21.225 -130.032 1.00 69.07 ? 120 GLN B O 1 +ATOM 6955 C CB . GLN C 1 58 ? -34.171 23.334 -132.299 1.00 75.56 ? 120 GLN B CB 1 +ATOM 6956 C CG . GLN C 1 58 ? -32.666 23.491 -132.515 1.00 87.11 ? 120 GLN B CG 1 +ATOM 6957 C CD . GLN C 1 58 ? -32.238 24.933 -132.756 1.00 104.31 ? 120 GLN B CD 1 +ATOM 6958 O OE1 . GLN C 1 58 ? -32.246 25.761 -131.841 1.00 105.19 ? 120 GLN B OE1 1 +ATOM 6959 N NE2 . GLN C 1 58 ? -31.872 25.239 -133.997 1.00 98.80 ? 120 GLN B NE2 1 +ATOM 6960 N N . GLU C 1 59 ? -35.018 22.226 -129.393 1.00 58.04 ? 121 GLU B N 1 +ATOM 6961 C CA . GLU C 1 59 ? -34.677 22.101 -127.981 1.00 62.48 ? 121 GLU B CA 1 +ATOM 6962 C C . GLU C 1 59 ? -34.734 20.648 -127.521 1.00 57.36 ? 121 GLU B C 1 +ATOM 6963 O O . GLU C 1 59 ? -33.858 20.191 -126.778 1.00 57.44 ? 121 GLU B O 1 +ATOM 6964 C CB . GLU C 1 59 ? -35.614 22.964 -127.138 1.00 70.65 ? 121 GLU B CB 1 +ATOM 6965 C CG . GLU C 1 59 ? -35.396 22.811 -125.645 1.00 74.38 ? 121 GLU B CG 1 +ATOM 6966 C CD . GLU C 1 59 ? -36.556 23.339 -124.824 1.00 79.65 ? 121 GLU B CD 1 +ATOM 6967 O OE1 . GLU C 1 59 ? -37.550 23.813 -125.419 1.00 75.02 ? 121 GLU B OE1 1 +ATOM 6968 O OE2 . GLU C 1 59 ? -36.481 23.258 -123.580 1.00 85.39 ? 121 GLU B OE2 1 +ATOM 6969 N N . ALA C 1 60 ? -35.757 19.909 -127.951 1.00 54.15 ? 122 ALA B N 1 +ATOM 6970 C CA . ALA C 1 60 ? -35.899 18.523 -127.523 1.00 47.94 ? 122 ALA B CA 1 +ATOM 6971 C C . ALA C 1 60 ? -34.771 17.659 -128.062 1.00 48.75 ? 122 ALA B C 1 +ATOM 6972 O O . ALA C 1 60 ? -34.247 16.799 -127.346 1.00 47.81 ? 122 ALA B O 1 +ATOM 6973 C CB . ALA C 1 60 ? -37.249 17.968 -127.968 1.00 51.50 ? 122 ALA B CB 1 +ATOM 6974 N N . LEU C 1 61 ? -34.403 17.852 -129.332 1.00 49.61 ? 123 LEU B N 1 +ATOM 6975 C CA . LEU C 1 61 ? -33.332 17.051 -129.913 1.00 52.32 ? 123 LEU B CA 1 +ATOM 6976 C C . LEU C 1 61 ? -32.004 17.278 -129.198 1.00 59.64 ? 123 LEU B C 1 +ATOM 6977 O O . LEU C 1 61 ? -31.217 16.337 -129.042 1.00 61.85 ? 123 LEU B O 1 +ATOM 6978 C CB . LEU C 1 61 ? -33.189 17.351 -131.406 1.00 47.65 ? 123 LEU B CB 1 +ATOM 6979 C CG . LEU C 1 61 ? -33.991 16.489 -132.394 1.00 49.79 ? 123 LEU B CG 1 +ATOM 6980 C CD1 . LEU C 1 61 ? -33.791 15.002 -132.121 1.00 52.34 ? 123 LEU B CD1 1 +ATOM 6981 C CD2 . LEU C 1 61 ? -35.468 16.831 -132.420 1.00 55.27 ? 123 LEU B CD2 1 +ATOM 6982 N N . ARG C 1 62 ? -31.742 18.504 -128.741 1.00 56.50 ? 124 ARG B N 1 +ATOM 6983 C CA . ARG C 1 62 ? -30.498 18.768 -128.023 1.00 52.59 ? 124 ARG B CA 1 +ATOM 6984 C C . ARG C 1 62 ? -30.488 18.085 -126.661 1.00 53.66 ? 124 ARG B C 1 +ATOM 6985 O O . ARG C 1 62 ? -29.497 17.449 -126.286 1.00 56.62 ? 124 ARG B O 1 +ATOM 6986 C CB . ARG C 1 62 ? -30.286 20.270 -127.865 1.00 59.58 ? 124 ARG B CB 1 +ATOM 6987 C CG . ARG C 1 62 ? -28.913 20.634 -127.329 1.00 70.30 ? 124 ARG B CG 1 +ATOM 6988 C CD . ARG C 1 62 ? -28.816 22.120 -127.017 1.00 87.19 ? 124 ARG B CD 1 +ATOM 6989 N NE . ARG C 1 62 ? -29.350 22.942 -128.100 1.00 92.17 ? 124 ARG B NE 1 +ATOM 6990 C CZ . ARG C 1 62 ? -30.465 23.664 -128.018 1.00 93.02 ? 124 ARG B CZ 1 +ATOM 6991 N NH1 . ARG C 1 62 ? -31.174 23.681 -126.894 1.00 82.29 ? 124 ARG B NH1 1 +ATOM 6992 N NH2 . ARG C 1 62 ? -30.867 24.376 -129.064 1.00 91.23 ? 124 ARG B NH2 1 +ATOM 6993 N N . TYR C 1 63 ? -31.580 18.213 -125.902 1.00 53.91 ? 125 TYR B N 1 +ATOM 6994 C CA . TYR C 1 63 ? -31.637 17.609 -124.573 1.00 53.32 ? 125 TYR B CA 1 +ATOM 6995 C C . TYR C 1 63 ? -31.530 16.095 -124.657 1.00 54.68 ? 125 TYR B C 1 +ATOM 6996 O O . TYR C 1 63 ? -30.778 15.469 -123.901 1.00 57.53 ? 125 TYR B O 1 +ATOM 6997 C CB . TYR C 1 63 ? -32.931 18.009 -123.865 1.00 47.96 ? 125 TYR B CB 1 +ATOM 6998 C CG . TYR C 1 63 ? -33.084 17.435 -122.472 1.00 50.11 ? 125 TYR B CG 1 +ATOM 6999 C CD1 . TYR C 1 63 ? -32.121 17.658 -121.493 1.00 64.05 ? 125 TYR B CD1 1 +ATOM 7000 C CD2 . TYR C 1 63 ? -34.193 16.668 -122.135 1.00 50.72 ? 125 TYR B CD2 1 +ATOM 7001 C CE1 . TYR C 1 63 ? -32.263 17.138 -120.213 1.00 65.78 ? 125 TYR B CE1 1 +ATOM 7002 C CE2 . TYR C 1 63 ? -34.344 16.145 -120.860 1.00 59.02 ? 125 TYR B CE2 1 +ATOM 7003 C CZ . TYR C 1 63 ? -33.375 16.383 -119.904 1.00 66.73 ? 125 TYR B CZ 1 +ATOM 7004 O OH . TYR C 1 63 ? -33.522 15.866 -118.636 1.00 66.75 ? 125 TYR B OH 1 +ATOM 7005 N N . TYR C 1 64 ? -32.283 15.484 -125.573 1.00 51.84 ? 126 TYR B N 1 +ATOM 7006 C CA . TYR C 1 64 ? -32.213 14.038 -125.726 1.00 47.56 ? 126 TYR B CA 1 +ATOM 7007 C C . TYR C 1 64 ? -30.834 13.588 -126.195 1.00 53.14 ? 126 TYR B C 1 +ATOM 7008 O O . TYR C 1 64 ? -30.413 12.467 -125.888 1.00 54.53 ? 126 TYR B O 1 +ATOM 7009 C CB . TYR C 1 64 ? -33.299 13.565 -126.686 1.00 42.55 ? 126 TYR B CB 1 +ATOM 7010 C CG . TYR C 1 64 ? -34.691 13.610 -126.101 1.00 40.13 ? 126 TYR B CG 1 +ATOM 7011 C CD1 . TYR C 1 64 ? -34.904 13.424 -124.741 1.00 44.42 ? 126 TYR B CD1 1 +ATOM 7012 C CD2 . TYR C 1 64 ? -35.794 13.828 -126.909 1.00 45.56 ? 126 TYR B CD2 1 +ATOM 7013 C CE1 . TYR C 1 64 ? -36.185 13.458 -124.205 1.00 46.63 ? 126 TYR B CE1 1 +ATOM 7014 C CE2 . TYR C 1 64 ? -37.075 13.862 -126.385 1.00 43.26 ? 126 TYR B CE2 1 +ATOM 7015 C CZ . TYR C 1 64 ? -37.265 13.678 -125.036 1.00 44.57 ? 126 TYR B CZ 1 +ATOM 7016 O OH . TYR C 1 64 ? -38.545 13.717 -124.532 1.00 44.54 ? 126 TYR B OH 1 +ATOM 7017 N N . ARG C 1 65 ? -30.118 14.437 -126.937 1.00 55.59 ? 127 ARG B N 1 +ATOM 7018 C CA . ARG C 1 65 ? -28.767 14.085 -127.367 1.00 58.05 ? 127 ARG B CA 1 +ATOM 7019 C C . ARG C 1 65 ? -27.773 14.110 -126.208 1.00 58.76 ? 127 ARG B C 1 +ATOM 7020 O O . ARG C 1 65 ? -26.827 13.312 -126.186 1.00 54.38 ? 127 ARG B O 1 +ATOM 7021 C CB . ARG C 1 65 ? -28.314 15.037 -128.474 1.00 60.17 ? 127 ARG B CB 1 +ATOM 7022 C CG . ARG C 1 65 ? -27.092 14.585 -129.252 1.00 58.48 ? 127 ARG B CG 1 +ATOM 7023 C CD . ARG C 1 65 ? -26.852 15.496 -130.449 1.00 64.39 ? 127 ARG B CD 1 +ATOM 7024 N NE . ARG C 1 65 ? -27.924 15.410 -131.443 1.00 76.41 ? 127 ARG B NE 1 +ATOM 7025 C CZ . ARG C 1 65 ? -28.871 16.330 -131.622 1.00 66.13 ? 127 ARG B CZ 1 +ATOM 7026 N NH1 . ARG C 1 65 ? -28.889 17.428 -130.875 1.00 63.01 ? 127 ARG B NH1 1 +ATOM 7027 N NH2 . ARG C 1 65 ? -29.798 16.154 -132.558 1.00 51.57 ? 127 ARG B NH2 1 +ATOM 7028 N N . ARG C 1 66 ? -27.972 15.005 -125.235 1.00 54.48 ? 128 ARG B N 1 +ATOM 7029 C CA . ARG C 1 66 ? -27.079 15.050 -124.082 1.00 50.97 ? 128 ARG B CA 1 +ATOM 7030 C C . ARG C 1 66 ? -27.281 13.844 -123.185 1.00 55.67 ? 128 ARG B C 1 +ATOM 7031 O O . ARG C 1 66 ? -26.307 13.248 -122.713 1.00 62.56 ? 128 ARG B O 1 +ATOM 7032 C CB . ARG C 1 66 ? -27.297 16.335 -123.288 1.00 56.70 ? 128 ARG B CB 1 +ATOM 7033 C CG . ARG C 1 66 ? -26.660 17.557 -123.914 1.00 73.40 ? 128 ARG B CG 1 +ATOM 7034 C CD . ARG C 1 66 ? -26.491 18.686 -122.903 1.00 86.76 ? 128 ARG B CD 1 +ATOM 7035 N NE . ARG C 1 66 ? -27.762 19.316 -122.552 1.00 94.33 ? 128 ARG B NE 1 +ATOM 7036 C CZ . ARG C 1 66 ? -28.216 20.440 -123.105 1.00 95.69 ? 128 ARG B CZ 1 +ATOM 7037 N NH1 . ARG C 1 66 ? -27.505 21.062 -124.041 1.00 85.73 ? 128 ARG B NH1 1 +ATOM 7038 N NH2 . ARG C 1 66 ? -29.385 20.943 -122.723 1.00 91.33 ? 128 ARG B NH2 1 +ATOM 7039 N N . LYS C 1 67 ? -28.539 13.467 -122.943 1.00 53.59 ? 129 LYS B N 1 +ATOM 7040 C CA . LYS C 1 67 ? -28.811 12.302 -122.109 1.00 59.57 ? 129 LYS B CA 1 +ATOM 7041 C C . LYS C 1 67 ? -28.252 11.026 -122.733 1.00 63.80 ? 129 LYS B C 1 +ATOM 7042 O O . LYS C 1 67 ? -27.906 10.083 -122.011 1.00 59.62 ? 129 LYS B O 1 +ATOM 7043 C CB . LYS C 1 67 ? -30.317 12.170 -121.861 1.00 51.56 ? 129 LYS B CB 1 +ATOM 7044 C CG . LYS C 1 67 ? -30.904 13.189 -120.885 1.00 46.25 ? 129 LYS B CG 1 +ATOM 7045 C CD . LYS C 1 67 ? -31.487 12.510 -119.642 1.00 61.55 ? 129 LYS B CD 1 +ATOM 7046 C CE . LYS C 1 67 ? -30.404 11.854 -118.785 1.00 63.44 ? 129 LYS B CE 1 +ATOM 7047 N NZ . LYS C 1 67 ? -30.942 11.131 -117.591 1.00 54.79 ? 129 LYS B NZ 1 +ATOM 7048 N N . VAL C 1 68 ? -28.161 10.977 -124.065 1.00 67.85 ? 130 VAL B N 1 +ATOM 7049 C CA . VAL C 1 68 ? -27.505 9.857 -124.736 1.00 66.93 ? 130 VAL B CA 1 +ATOM 7050 C C . VAL C 1 68 ? -25.994 9.932 -124.554 1.00 69.66 ? 130 VAL B C 1 +ATOM 7051 O O . VAL C 1 68 ? -25.320 8.907 -124.389 1.00 72.56 ? 130 VAL B O 1 +ATOM 7052 C CB . VAL C 1 68 ? -27.896 9.819 -126.222 1.00 56.74 ? 130 VAL B CB 1 +ATOM 7053 C CG1 . VAL C 1 68 ? -27.023 8.830 -126.977 1.00 58.37 ? 130 VAL B CG1 1 +ATOM 7054 C CG2 . VAL C 1 68 ? -29.361 9.446 -126.366 1.00 52.14 ? 130 VAL B CG2 1 +ATOM 7055 N N . ALA C 1 69 ? -25.433 11.141 -124.602 1.00 65.84 ? 131 ALA B N 1 +ATOM 7056 C CA . ALA C 1 69 ? -24.006 11.292 -124.347 1.00 67.85 ? 131 ALA B CA 1 +ATOM 7057 C C . ALA C 1 69 ? -23.669 10.893 -122.916 1.00 75.50 ? 131 ALA B C 1 +ATOM 7058 O O . ALA C 1 69 ? -22.731 10.123 -122.678 1.00 77.61 ? 131 ALA B O 1 +ATOM 7059 C CB . ALA C 1 69 ? -23.574 12.731 -124.626 1.00 63.85 ? 131 ALA B CB 1 +ATOM 7060 N N . ARG C 1 70 ? -24.458 11.372 -121.949 1.00 74.50 ? 132 ARG B N 1 +ATOM 7061 C CA . ARG C 1 70 ? -24.194 11.043 -120.553 1.00 78.50 ? 132 ARG B CA 1 +ATOM 7062 C C . ARG C 1 70 ? -24.392 9.558 -120.280 1.00 75.54 ? 132 ARG B C 1 +ATOM 7063 O O . ARG C 1 70 ? -23.670 8.982 -119.458 1.00 77.56 ? 132 ARG B O 1 +ATOM 7064 C CB . ARG C 1 70 ? -25.089 11.878 -119.632 1.00 80.01 ? 132 ARG B CB 1 +ATOM 7065 C CG . ARG C 1 70 ? -24.805 13.369 -119.668 1.00 81.56 ? 132 ARG B CG 1 +ATOM 7066 C CD . ARG C 1 70 ? -25.634 14.127 -118.637 1.00 99.05 ? 132 ARG B CD 1 +ATOM 7067 N NE . ARG C 1 70 ? -25.397 15.567 -118.711 1.00 119.62 ? 132 ARG B NE 1 +ATOM 7068 C CZ . ARG C 1 70 ? -26.012 16.472 -117.955 1.00 119.43 ? 132 ARG B CZ 1 +ATOM 7069 N NH1 . ARG C 1 70 ? -26.910 16.089 -117.054 1.00 118.44 ? 132 ARG B NH1 1 +ATOM 7070 N NH2 . ARG C 1 70 ? -25.729 17.761 -118.099 1.00 108.11 ? 132 ARG B NH2 1 +ATOM 7071 N N . TRP C 1 71 ? -25.353 8.923 -120.957 1.00 70.56 ? 133 TRP B N 1 +ATOM 7072 C CA . TRP C 1 71 ? -25.573 7.494 -120.758 1.00 77.16 ? 133 TRP B CA 1 +ATOM 7073 C C . TRP C 1 71 ? -24.387 6.680 -121.266 1.00 76.26 ? 133 TRP B C 1 +ATOM 7074 O O . TRP C 1 71 ? -24.020 5.665 -120.661 1.00 81.12 ? 133 TRP B O 1 +ATOM 7075 C CB . TRP C 1 71 ? -26.874 7.049 -121.432 1.00 70.73 ? 133 TRP B CB 1 +ATOM 7076 C CG . TRP C 1 71 ? -27.290 5.639 -121.068 1.00 66.73 ? 133 TRP B CG 1 +ATOM 7077 C CD1 . TRP C 1 71 ? -28.121 5.265 -120.050 1.00 71.34 ? 133 TRP B CD1 1 +ATOM 7078 C CD2 . TRP C 1 71 ? -26.903 4.430 -121.731 1.00 64.34 ? 133 TRP B CD2 1 +ATOM 7079 N NE1 . TRP C 1 71 ? -28.261 3.898 -120.029 1.00 72.15 ? 133 TRP B NE1 1 +ATOM 7080 C CE2 . TRP C 1 71 ? -27.526 3.362 -121.054 1.00 68.20 ? 133 TRP B CE2 1 +ATOM 7081 C CE3 . TRP C 1 71 ? -26.087 4.147 -122.829 1.00 63.28 ? 133 TRP B CE3 1 +ATOM 7082 C CZ2 . TRP C 1 71 ? -27.361 2.036 -121.441 1.00 66.86 ? 133 TRP B CZ2 1 +ATOM 7083 C CZ3 . TRP C 1 71 ? -25.925 2.830 -123.212 1.00 66.47 ? 133 TRP B CZ3 1 +ATOM 7084 C CH2 . TRP C 1 71 ? -26.559 1.790 -122.520 1.00 68.04 ? 133 TRP B CH2 1 +ATOM 7085 N N . ASN C 1 72 ? -23.816 7.067 -122.408 1.00 69.69 ? 134 ASN B N 1 +ATOM 7086 C CA . ASN C 1 72 ? -22.698 6.310 -122.961 1.00 77.46 ? 134 ASN B CA 1 +ATOM 7087 C C . ASN C 1 72 ? -21.467 6.379 -122.061 1.00 83.80 ? 134 ASN B C 1 +ATOM 7088 O O . ASN C 1 72 ? -20.728 5.395 -121.929 1.00 80.86 ? 134 ASN B O 1 +ATOM 7089 C CB . ASN C 1 72 ? -22.378 6.817 -124.364 1.00 79.82 ? 134 ASN B CB 1 +ATOM 7090 C CG . ASN C 1 72 ? -23.357 6.304 -125.392 1.00 80.79 ? 134 ASN B CG 1 +ATOM 7091 O OD1 . ASN C 1 72 ? -23.776 5.145 -125.332 1.00 78.14 ? 134 ASN B OD1 1 +ATOM 7092 N ND2 . ASN C 1 72 ? -23.741 7.161 -126.335 1.00 76.54 ? 134 ASN B ND2 1 +ATOM 7093 N N . ARG C 1 73 ? -21.242 7.524 -121.414 1.00 83.85 ? 135 ARG B N 1 +ATOM 7094 C CA . ARG C 1 73 ? -20.129 7.639 -120.474 1.00 84.10 ? 135 ARG B CA 1 +ATOM 7095 C C . ARG C 1 73 ? -20.374 6.806 -119.220 1.00 83.47 ? 135 ARG B C 1 +ATOM 7096 O O . ARG C 1 73 ? -19.565 5.939 -118.866 1.00 79.97 ? 135 ARG B O 1 +ATOM 7097 C CB . ARG C 1 73 ? -19.912 9.099 -120.096 1.00 82.91 ? 135 ARG B CB 1 +ATOM 7098 C CG . ARG C 1 73 ? -18.845 9.819 -120.882 1.00 79.58 ? 135 ARG B CG 1 +ATOM 7099 C CD . ARG C 1 73 ? -18.614 11.189 -120.271 1.00 89.59 ? 135 ARG B CD 1 +ATOM 7100 N NE . ARG C 1 73 ? -18.234 11.096 -118.857 1.00 114.39 ? 135 ARG B NE 1 +ATOM 7101 C CZ . ARG C 1 73 ? -18.999 11.441 -117.822 1.00 118.46 ? 135 ARG B CZ 1 +ATOM 7102 N NH1 . ARG C 1 73 ? -20.218 11.923 -118.017 1.00 118.14 ? 135 ARG B NH1 1 +ATOM 7103 N NH2 . ARG C 1 73 ? -18.535 11.307 -116.585 1.00 99.33 ? 135 ARG B NH2 1 +ATOM 7104 N N . ARG C 1 74 ? -21.509 7.043 -118.548 1.00 79.92 ? 136 ARG B N 1 +ATOM 7105 C CA . ARG C 1 74 ? -21.775 6.446 -117.240 1.00 83.16 ? 136 ARG B CA 1 +ATOM 7106 C C . ARG C 1 74 ? -21.937 4.930 -117.319 1.00 88.97 ? 136 ARG B C 1 +ATOM 7107 O O . ARG C 1 74 ? -21.683 4.229 -116.333 1.00 84.46 ? 136 ARG B O 1 +ATOM 7108 C CB . ARG C 1 74 ? -23.036 7.090 -116.651 1.00 81.96 ? 136 ARG B CB 1 +ATOM 7109 C CG . ARG C 1 74 ? -22.825 8.522 -116.191 1.00 84.22 ? 136 ARG B CG 1 +ATOM 7110 C CD . ARG C 1 74 ? -23.947 9.039 -115.311 1.00 78.43 ? 136 ARG B CD 1 +ATOM 7111 N NE . ARG C 1 74 ? -23.758 10.461 -115.032 1.00 87.09 ? 136 ARG B NE 1 +ATOM 7112 C CZ . ARG C 1 74 ? -24.694 11.258 -114.530 1.00 97.70 ? 136 ARG B CZ 1 +ATOM 7113 N NH1 . ARG C 1 74 ? -25.896 10.773 -114.254 1.00 92.14 ? 136 ARG B NH1 1 +ATOM 7114 N NH2 . ARG C 1 74 ? -24.432 12.541 -114.311 1.00 108.31 ? 136 ARG B NH2 1 +ATOM 7115 N N . HIS C 1 75 ? -22.383 4.414 -118.472 1.00 91.02 ? 137 HIS B N 1 +ATOM 7116 C CA . HIS C 1 75 ? -22.508 2.972 -118.672 1.00 85.65 ? 137 HIS B CA 1 +ATOM 7117 C C . HIS C 1 75 ? -21.159 2.345 -118.998 1.00 87.46 ? 137 HIS B C 1 +ATOM 7118 O O . HIS C 1 75 ? -20.876 1.218 -118.573 1.00 97.45 ? 137 HIS B O 1 +ATOM 7119 C CB . HIS C 1 75 ? -23.512 2.673 -119.788 1.00 78.27 ? 137 HIS B CB 1 +ATOM 7120 C CG . HIS C 1 75 ? -23.494 1.251 -120.265 1.00 86.64 ? 137 HIS B CG 1 +ATOM 7121 N ND1 . HIS C 1 75 ? -24.099 0.225 -119.571 1.00 93.92 ? 137 HIS B ND1 1 +ATOM 7122 C CD2 . HIS C 1 75 ? -22.947 0.687 -121.370 1.00 82.20 ? 137 HIS B CD2 1 +ATOM 7123 C CE1 . HIS C 1 75 ? -23.925 -0.909 -120.227 1.00 87.03 ? 137 HIS B CE1 1 +ATOM 7124 N NE2 . HIS C 1 75 ? -23.230 -0.656 -121.322 1.00 83.07 ? 137 HIS B NE2 1 +ATOM 7125 N N . LYS C 1 76 ? -20.316 3.065 -119.748 1.00 75.65 ? 138 LYS B N 1 +ATOM 7126 C CA . LYS C 1 76 ? -18.968 2.583 -120.031 1.00 75.90 ? 138 LYS B CA 1 +ATOM 7127 C C . LYS C 1 76 ? -18.169 2.374 -118.750 1.00 83.15 ? 138 LYS B C 1 +ATOM 7128 O O . LYS C 1 76 ? -17.470 1.363 -118.600 1.00 83.99 ? 138 LYS B O 1 +ATOM 7129 C CB . LYS C 1 76 ? -18.251 3.563 -120.957 1.00 64.37 ? 138 LYS B CB 1 +ATOM 7130 C CG . LYS C 1 76 ? -16.755 3.320 -121.035 1.00 65.69 ? 138 LYS B CG 1 +ATOM 7131 C CD . LYS C 1 76 ? -16.075 4.244 -122.023 1.00 66.08 ? 138 LYS B CD 1 +ATOM 7132 C CE . LYS C 1 76 ? -16.496 3.918 -123.455 1.00 72.45 ? 138 LYS B CE 1 +ATOM 7133 N NZ . LYS C 1 76 ? -16.191 2.516 -123.887 1.00 83.49 ? 138 LYS B NZ 1 +ATOM 7134 N N . MET C 1 77 ? -18.282 3.306 -117.803 1.00 86.47 ? 139 MET B N 1 +ATOM 7135 C CA . MET C 1 77 ? -17.603 3.142 -116.524 1.00 86.82 ? 139 MET B CA 1 +ATOM 7136 C C . MET C 1 77 ? -18.141 1.933 -115.771 1.00 90.25 ? 139 MET B C 1 +ATOM 7137 O O . MET C 1 77 ? -17.372 1.180 -115.164 1.00 91.42 ? 139 MET B O 1 +ATOM 7138 C CB . MET C 1 77 ? -17.761 4.411 -115.687 1.00 89.06 ? 139 MET B CB 1 +ATOM 7139 C CG . MET C 1 77 ? -17.088 5.637 -116.277 1.00 85.26 ? 139 MET B CG 1 +ATOM 7140 S SD . MET C 1 77 ? -16.982 6.987 -115.089 1.00 90.80 ? 139 MET B SD 1 +ATOM 7141 C CE . MET C 1 77 ? -15.563 6.482 -114.122 1.00 77.16 ? 139 MET B CE 1 +ATOM 7142 N N . TYR C 1 78 ? -19.455 1.721 -115.808 1.00 86.08 ? 140 TYR B N 1 +ATOM 7143 C CA . TYR C 1 78 ? -20.043 0.551 -115.173 1.00 85.55 ? 140 TYR B CA 1 +ATOM 7144 C C . TYR C 1 78 ? -19.667 -0.711 -115.949 1.00 89.33 ? 140 TYR B C 1 +ATOM 7145 O O . TYR C 1 78 ? -19.220 -1.701 -115.367 1.00 95.26 ? 140 TYR B O 1 +ATOM 7146 C CB . TYR C 1 78 ? -21.566 0.680 -115.071 1.00 75.68 ? 140 TYR B CB 1 +ATOM 7147 C CG . TYR C 1 78 ? -22.190 -0.446 -114.273 1.00 84.22 ? 140 TYR B CG 1 +ATOM 7148 C CD1 . TYR C 1 78 ? -22.201 -0.415 -112.882 1.00 91.90 ? 140 TYR B CD1 1 +ATOM 7149 C CD2 . TYR C 1 78 ? -22.746 -1.553 -114.907 1.00 85.53 ? 140 TYR B CD2 1 +ATOM 7150 C CE1 . TYR C 1 78 ? -22.758 -1.451 -112.142 1.00 92.84 ? 140 TYR B CE1 1 +ATOM 7151 C CE2 . TYR C 1 78 ? -23.308 -2.595 -114.176 1.00 87.42 ? 140 TYR B CE2 1 +ATOM 7152 C CZ . TYR C 1 78 ? -23.311 -2.539 -112.794 1.00 93.23 ? 140 TYR B CZ 1 +ATOM 7153 O OH . TYR C 1 78 ? -23.869 -3.568 -112.061 1.00 86.53 ? 140 TYR B OH 1 +ATOM 7154 N N . PRO C 1 89 ? -20.567 -0.761 -130.353 1.00 81.15 ? 151 PRO B N 1 +ATOM 7155 C CA . PRO C 1 89 ? -20.477 0.698 -130.487 1.00 83.09 ? 151 PRO B CA 1 +ATOM 7156 C C . PRO C 1 89 ? -21.346 1.435 -129.467 1.00 80.05 ? 151 PRO B C 1 +ATOM 7157 O O . PRO C 1 89 ? -22.204 0.805 -128.846 1.00 73.04 ? 151 PRO B O 1 +ATOM 7158 C CB . PRO C 1 89 ? -20.979 0.945 -131.914 1.00 79.33 ? 151 PRO B CB 1 +ATOM 7159 C CG . PRO C 1 89 ? -21.878 -0.209 -132.206 1.00 68.68 ? 151 PRO B CG 1 +ATOM 7160 C CD . PRO C 1 89 ? -21.300 -1.385 -131.470 1.00 58.85 ? 151 PRO B CD 1 +ATOM 7161 N N . PRO C 1 90 ? -21.116 2.734 -129.277 1.00 84.82 ? 152 PRO B N 1 +ATOM 7162 C CA . PRO C 1 90 ? -21.959 3.501 -128.353 1.00 83.99 ? 152 PRO B CA 1 +ATOM 7163 C C . PRO C 1 90 ? -23.326 3.775 -128.961 1.00 79.30 ? 152 PRO B C 1 +ATOM 7164 O O . PRO C 1 90 ? -23.561 3.593 -130.158 1.00 74.68 ? 152 PRO B O 1 +ATOM 7165 C CB . PRO C 1 90 ? -21.172 4.797 -128.133 1.00 85.90 ? 152 PRO B CB 1 +ATOM 7166 C CG . PRO C 1 90 ? -20.340 4.937 -129.363 1.00 81.80 ? 152 PRO B CG 1 +ATOM 7167 C CD . PRO C 1 90 ? -19.985 3.536 -129.782 1.00 79.90 ? 152 PRO B CD 1 +ATOM 7168 N N . LEU C 1 91 ? -24.232 4.238 -128.104 1.00 78.64 ? 153 LEU B N 1 +ATOM 7169 C CA . LEU C 1 91 ? -25.597 4.527 -128.521 1.00 65.25 ? 153 LEU B CA 1 +ATOM 7170 C C . LEU C 1 91 ? -25.633 5.677 -129.520 1.00 66.68 ? 153 LEU B C 1 +ATOM 7171 O O . LEU C 1 91 ? -24.837 6.618 -129.453 1.00 64.65 ? 153 LEU B O 1 +ATOM 7172 C CB . LEU C 1 91 ? -26.463 4.864 -127.310 1.00 60.68 ? 153 LEU B CB 1 +ATOM 7173 C CG . LEU C 1 91 ? -27.716 4.008 -127.147 1.00 63.48 ? 153 LEU B CG 1 +ATOM 7174 C CD1 . LEU C 1 91 ? -28.583 4.104 -128.393 1.00 68.17 ? 153 LEU B CD1 1 +ATOM 7175 C CD2 . LEU C 1 91 ? -27.344 2.561 -126.858 1.00 62.81 ? 153 LEU B CD2 1 +ATOM 7176 N N . GLN C 1 92 ? -26.574 5.588 -130.456 1.00 67.25 ? 154 GLN B N 1 +ATOM 7177 C CA . GLN C 1 92 ? -26.819 6.619 -131.455 1.00 70.25 ? 154 GLN B CA 1 +ATOM 7178 C C . GLN C 1 92 ? -28.257 7.097 -131.320 1.00 60.62 ? 154 GLN B C 1 +ATOM 7179 O O . GLN C 1 92 ? -29.188 6.285 -131.348 1.00 63.80 ? 154 GLN B O 1 +ATOM 7180 C CB . GLN C 1 92 ? -26.568 6.082 -132.869 1.00 78.21 ? 154 GLN B CB 1 +ATOM 7181 C CG . GLN C 1 92 ? -26.453 7.141 -133.957 1.00 73.94 ? 154 GLN B CG 1 +ATOM 7182 C CD . GLN C 1 92 ? -25.053 7.707 -134.067 1.00 81.33 ? 154 GLN B CD 1 +ATOM 7183 O OE1 . GLN C 1 92 ? -24.202 7.462 -133.210 1.00 79.67 ? 154 GLN B OE1 1 +ATOM 7184 N NE2 . GLN C 1 92 ? -24.798 8.450 -135.139 1.00 84.09 ? 154 GLN B NE2 1 +ATOM 7185 N N . LEU C 1 93 ? -28.439 8.404 -131.168 1.00 48.05 ? 155 LEU B N 1 +ATOM 7186 C CA . LEU C 1 93 ? -29.770 8.987 -131.050 1.00 47.49 ? 155 LEU B CA 1 +ATOM 7187 C C . LEU C 1 93 ? -30.248 9.384 -132.443 1.00 59.83 ? 155 LEU B C 1 +ATOM 7188 O O . LEU C 1 93 ? -29.812 10.404 -132.987 1.00 67.87 ? 155 LEU B O 1 +ATOM 7189 C CB . LEU C 1 93 ? -29.747 10.182 -130.102 1.00 44.97 ? 155 LEU B CB 1 +ATOM 7190 C CG . LEU C 1 93 ? -31.084 10.812 -129.709 1.00 44.74 ? 155 LEU B CG 1 +ATOM 7191 C CD1 . LEU C 1 93 ? -31.447 11.951 -130.652 1.00 48.31 ? 155 LEU B CD1 1 +ATOM 7192 C CD2 . LEU C 1 93 ? -32.190 9.760 -129.652 1.00 38.00 ? 155 LEU B CD2 1 +ATOM 7193 N N . ARG C 1 94 ? -31.161 8.601 -133.010 1.00 56.35 ? 156 ARG B N 1 +ATOM 7194 C CA . ARG C 1 94 ? -31.666 8.857 -134.350 1.00 57.05 ? 156 ARG B CA 1 +ATOM 7195 C C . ARG C 1 94 ? -33.044 9.498 -134.284 1.00 52.88 ? 156 ARG B C 1 +ATOM 7196 O O . ARG C 1 94 ? -33.910 9.068 -133.515 1.00 48.28 ? 156 ARG B O 1 +ATOM 7197 C CB . ARG C 1 94 ? -31.725 7.571 -135.182 1.00 64.12 ? 156 ARG B CB 1 +ATOM 7198 C CG . ARG C 1 94 ? -30.381 7.129 -135.756 1.00 76.76 ? 156 ARG B CG 1 +ATOM 7199 C CD . ARG C 1 94 ? -30.549 6.047 -136.819 1.00 83.71 ? 156 ARG B CD 1 +ATOM 7200 N NE . ARG C 1 94 ? -30.981 4.771 -136.247 1.00 96.10 ? 156 ARG B NE 1 +ATOM 7201 C CZ . ARG C 1 94 ? -30.159 3.805 -135.844 1.00 100.45 ? 156 ARG B CZ 1 +ATOM 7202 N NH1 . ARG C 1 94 ? -28.843 3.954 -135.944 1.00 91.20 ? 156 ARG B NH1 1 +ATOM 7203 N NH2 . ARG C 1 94 ? -30.655 2.683 -135.337 1.00 105.91 ? 156 ARG B NH2 1 +ATOM 7204 N N . LEU C 1 95 ? -33.237 10.535 -135.102 1.00 53.25 ? 157 LEU B N 1 +ATOM 7205 C CA . LEU C 1 95 ? -34.532 11.197 -135.183 1.00 44.21 ? 157 LEU B CA 1 +ATOM 7206 C C . LEU C 1 95 ? -35.619 10.230 -135.621 1.00 41.82 ? 157 LEU B C 1 +ATOM 7207 O O . LEU C 1 95 ? -36.783 10.385 -135.241 1.00 44.72 ? 157 LEU B O 1 +ATOM 7208 C CB . LEU C 1 95 ? -34.449 12.362 -136.163 1.00 45.26 ? 157 LEU B CB 1 +ATOM 7209 C CG . LEU C 1 95 ? -35.036 13.708 -135.758 1.00 46.90 ? 157 LEU B CG 1 +ATOM 7210 C CD1 . LEU C 1 95 ? -35.035 14.628 -136.964 1.00 45.32 ? 157 LEU B CD1 1 +ATOM 7211 C CD2 . LEU C 1 95 ? -36.438 13.551 -135.201 1.00 54.88 ? 157 LEU B CD2 1 +ATOM 7212 N N . GLU C 1 96 ? -35.253 9.212 -136.392 1.00 41.44 ? 158 GLU B N 1 +ATOM 7213 C CA . GLU C 1 96 ? -36.210 8.241 -136.893 1.00 42.43 ? 158 GLU B CA 1 +ATOM 7214 C C . GLU C 1 96 ? -36.712 7.285 -135.815 1.00 40.26 ? 158 GLU B C 1 +ATOM 7215 O O . GLU C 1 96 ? -37.480 6.377 -136.144 1.00 38.00 ? 158 GLU B O 1 +ATOM 7216 C CB . GLU C 1 96 ? -35.582 7.440 -138.037 1.00 52.93 ? 158 GLU B CB 1 +ATOM 7217 C CG . GLU C 1 96 ? -34.817 8.280 -139.056 1.00 53.14 ? 158 GLU B CG 1 +ATOM 7218 C CD . GLU C 1 96 ? -33.342 8.437 -138.698 1.00 68.15 ? 158 GLU B CD 1 +ATOM 7219 O OE1 . GLU C 1 96 ? -32.974 9.497 -138.148 1.00 68.76 ? 158 GLU B OE1 1 +ATOM 7220 O OE2 . GLU C 1 96 ? -32.559 7.488 -138.929 1.00 69.13 ? 158 GLU B OE2 1 +ATOM 7221 N N . ALA C 1 97 ? -36.298 7.447 -134.558 1.00 39.81 ? 159 ALA B N 1 +ATOM 7222 C CA . ALA C 1 97 ? -36.744 6.554 -133.496 1.00 38.00 ? 159 ALA B CA 1 +ATOM 7223 C C . ALA C 1 97 ? -38.210 6.798 -133.156 1.00 38.00 ? 159 ALA B C 1 +ATOM 7224 O O . ALA C 1 97 ? -38.735 7.903 -133.317 1.00 39.79 ? 159 ALA B O 1 +ATOM 7225 C CB . ALA C 1 97 ? -35.880 6.731 -132.251 1.00 38.00 ? 159 ALA B CB 1 +ATOM 7226 N N . SER C 1 98 ? -38.873 5.747 -132.668 1.00 38.00 ? 160 SER B N 1 +ATOM 7227 C CA . SER C 1 98 ? -40.311 5.833 -132.434 1.00 38.00 ? 160 SER B CA 1 +ATOM 7228 C C . SER C 1 98 ? -40.643 6.829 -131.331 1.00 38.30 ? 160 SER B C 1 +ATOM 7229 O O . SER C 1 98 ? -41.454 7.739 -131.531 1.00 39.96 ? 160 SER B O 1 +ATOM 7230 C CB . SER C 1 98 ? -40.873 4.455 -132.098 1.00 38.00 ? 160 SER B CB 1 +ATOM 7231 O OG . SER C 1 98 ? -40.568 3.535 -133.126 1.00 42.04 ? 160 SER B OG 1 +ATOM 7232 N N . TRP C 1 99 ? -40.027 6.677 -130.158 1.00 38.00 ? 161 TRP B N 1 +ATOM 7233 C CA . TRP C 1 99 ? -40.362 7.565 -129.052 1.00 38.00 ? 161 TRP B CA 1 +ATOM 7234 C C . TRP C 1 99 ? -40.034 9.016 -129.374 1.00 39.03 ? 161 TRP B C 1 +ATOM 7235 O O . TRP C 1 99 ? -40.737 9.924 -128.918 1.00 44.66 ? 161 TRP B O 1 +ATOM 7236 C CB . TRP C 1 99 ? -39.637 7.122 -127.785 1.00 42.66 ? 161 TRP B CB 1 +ATOM 7237 C CG . TRP C 1 99 ? -38.164 7.228 -127.888 1.00 40.19 ? 161 TRP B CG 1 +ATOM 7238 C CD1 . TRP C 1 99 ? -37.320 6.333 -128.469 1.00 41.38 ? 161 TRP B CD1 1 +ATOM 7239 C CD2 . TRP C 1 99 ? -37.350 8.295 -127.400 1.00 38.00 ? 161 TRP B CD2 1 +ATOM 7240 N NE1 . TRP C 1 99 ? -36.025 6.777 -128.371 1.00 41.80 ? 161 TRP B NE1 1 +ATOM 7241 C CE2 . TRP C 1 99 ? -36.018 7.980 -127.717 1.00 38.00 ? 161 TRP B CE2 1 +ATOM 7242 C CE3 . TRP C 1 99 ? -37.618 9.485 -126.726 1.00 38.00 ? 161 TRP B CE3 1 +ATOM 7243 C CZ2 . TRP C 1 99 ? -34.957 8.814 -127.385 1.00 38.00 ? 161 TRP B CZ2 1 +ATOM 7244 C CZ3 . TRP C 1 99 ? -36.563 10.309 -126.395 1.00 38.88 ? 161 TRP B CZ3 1 +ATOM 7245 C CH2 . TRP C 1 99 ? -35.249 9.970 -126.724 1.00 38.50 ? 161 TRP B CH2 1 +ATOM 7246 N N . VAL C 1 100 ? -38.993 9.256 -130.175 1.00 38.00 ? 162 VAL B N 1 +ATOM 7247 C CA . VAL C 1 100 ? -38.660 10.622 -130.569 1.00 40.02 ? 162 VAL B CA 1 +ATOM 7248 C C . VAL C 1 100 ? -39.780 11.213 -131.415 1.00 46.43 ? 162 VAL B C 1 +ATOM 7249 O O . VAL C 1 100 ? -40.261 12.324 -131.160 1.00 47.35 ? 162 VAL B O 1 +ATOM 7250 C CB . VAL C 1 100 ? -37.312 10.656 -131.309 1.00 42.40 ? 162 VAL B CB 1 +ATOM 7251 C CG1 . VAL C 1 100 ? -36.931 12.087 -131.663 1.00 38.00 ? 162 VAL B CG1 1 +ATOM 7252 C CG2 . VAL C 1 100 ? -36.241 10.016 -130.461 1.00 40.24 ? 162 VAL B CG2 1 +ATOM 7253 N N . GLN C 1 101 ? -40.219 10.472 -132.435 1.00 48.45 ? 163 GLN B N 1 +ATOM 7254 C CA . GLN C 1 101 ? -41.318 10.950 -133.265 1.00 48.02 ? 163 GLN B CA 1 +ATOM 7255 C C . GLN C 1 101 ? -42.614 11.035 -132.469 1.00 46.85 ? 163 GLN B C 1 +ATOM 7256 O O . GLN C 1 101 ? -43.413 11.954 -132.679 1.00 44.04 ? 163 GLN B O 1 +ATOM 7257 C CB . GLN C 1 101 ? -41.484 10.026 -134.473 1.00 46.23 ? 163 GLN B CB 1 +ATOM 7258 C CG . GLN C 1 101 ? -41.770 10.739 -135.777 1.00 45.78 ? 163 GLN B CG 1 +ATOM 7259 C CD . GLN C 1 101 ? -40.629 11.638 -136.191 1.00 44.56 ? 163 GLN B CD 1 +ATOM 7260 O OE1 . GLN C 1 101 ? -39.488 11.449 -135.767 1.00 40.00 ? 163 GLN B OE1 1 +ATOM 7261 N NE2 . GLN C 1 101 ? -40.928 12.620 -137.030 1.00 45.67 ? 163 GLN B NE2 1 +ATOM 7262 N N . PHE C 1 102 ? -42.811 10.122 -131.517 1.00 46.68 ? 164 PHE B N 1 +ATOM 7263 C CA . PHE C 1 102 ? -43.993 10.186 -130.668 1.00 41.91 ? 164 PHE B CA 1 +ATOM 7264 C C . PHE C 1 102 ? -43.995 11.457 -129.830 1.00 42.82 ? 164 PHE B C 1 +ATOM 7265 O O . PHE C 1 102 ? -45.023 12.135 -129.722 1.00 44.30 ? 164 PHE B O 1 +ATOM 7266 C CB . PHE C 1 102 ? -44.050 8.946 -129.775 1.00 38.44 ? 164 PHE B CB 1 +ATOM 7267 C CG . PHE C 1 102 ? -45.028 9.056 -128.642 1.00 43.36 ? 164 PHE B CG 1 +ATOM 7268 C CD1 . PHE C 1 102 ? -46.378 9.239 -128.887 1.00 45.92 ? 164 PHE B CD1 1 +ATOM 7269 C CD2 . PHE C 1 102 ? -44.597 8.974 -127.328 1.00 42.05 ? 164 PHE B CD2 1 +ATOM 7270 C CE1 . PHE C 1 102 ? -47.278 9.337 -127.841 1.00 45.18 ? 164 PHE B CE1 1 +ATOM 7271 C CE2 . PHE C 1 102 ? -45.492 9.071 -126.282 1.00 38.00 ? 164 PHE B CE2 1 +ATOM 7272 C CZ . PHE C 1 102 ? -46.831 9.252 -126.538 1.00 39.92 ? 164 PHE B CZ 1 +ATOM 7273 N N . HIS C 1 103 ? -42.839 11.818 -129.268 1.00 41.01 ? 165 HIS B N 1 +ATOM 7274 C CA . HIS C 1 103 ? -42.758 12.990 -128.401 1.00 41.24 ? 165 HIS B CA 1 +ATOM 7275 C C . HIS C 1 103 ? -42.982 14.282 -129.173 1.00 43.20 ? 165 HIS B C 1 +ATOM 7276 O O . HIS C 1 103 ? -43.718 15.167 -128.722 1.00 45.84 ? 165 HIS B O 1 +ATOM 7277 C CB . HIS C 1 103 ? -41.403 13.024 -127.702 1.00 42.44 ? 165 HIS B CB 1 +ATOM 7278 C CG . HIS C 1 103 ? -41.234 11.963 -126.665 1.00 41.37 ? 165 HIS B CG 1 +ATOM 7279 N ND1 . HIS C 1 103 ? -40.145 11.913 -125.824 1.00 40.19 ? 165 HIS B ND1 1 +ATOM 7280 C CD2 . HIS C 1 103 ? -42.016 10.908 -126.335 1.00 38.09 ? 165 HIS B CD2 1 +ATOM 7281 C CE1 . HIS C 1 103 ? -40.264 10.874 -125.018 1.00 44.73 ? 165 HIS B CE1 1 +ATOM 7282 N NE2 . HIS C 1 103 ? -41.389 10.246 -125.309 1.00 39.98 ? 165 HIS B NE2 1 +ATOM 7283 N N . LEU C 1 104 ? -42.341 14.421 -130.331 1.00 43.18 ? 166 LEU B N 1 +ATOM 7284 C CA . LEU C 1 104 ? -42.539 15.621 -131.131 1.00 46.90 ? 166 LEU B CA 1 +ATOM 7285 C C . LEU C 1 104 ? -43.926 15.681 -131.751 1.00 53.67 ? 166 LEU B C 1 +ATOM 7286 O O . LEU C 1 104 ? -44.316 16.744 -132.250 1.00 52.21 ? 166 LEU B O 1 +ATOM 7287 C CB . LEU C 1 104 ? -41.476 15.702 -132.224 1.00 44.27 ? 166 LEU B CB 1 +ATOM 7288 C CG . LEU C 1 104 ? -40.033 15.723 -131.725 1.00 38.00 ? 166 LEU B CG 1 +ATOM 7289 C CD1 . LEU C 1 104 ? -39.097 15.093 -132.750 1.00 38.00 ? 166 LEU B CD1 1 +ATOM 7290 C CD2 . LEU C 1 104 ? -39.622 17.147 -131.410 1.00 38.00 ? 166 LEU B CD2 1 +ATOM 7291 N N . GLY C 1 105 ? -44.673 14.576 -131.720 1.00 51.43 ? 167 GLY B N 1 +ATOM 7292 C CA . GLY C 1 105 ? -46.010 14.460 -132.258 1.00 51.17 ? 167 GLY B CA 1 +ATOM 7293 C C . GLY C 1 105 ? -47.133 14.696 -131.281 1.00 49.31 ? 167 GLY B C 1 +ATOM 7294 O O . GLY C 1 105 ? -48.299 14.501 -131.641 1.00 50.50 ? 167 GLY B O 1 +ATOM 7295 N N . ILE C 1 106 ? -46.817 15.072 -130.043 1.00 51.83 ? 168 ILE B N 1 +ATOM 7296 C CA . ILE C 1 106 ? -47.833 15.426 -129.056 1.00 58.76 ? 168 ILE B CA 1 +ATOM 7297 C C . ILE C 1 106 ? -48.220 16.886 -129.261 1.00 58.87 ? 168 ILE B C 1 +ATOM 7298 O O . ILE C 1 106 ? -47.395 17.791 -129.089 1.00 53.43 ? 168 ILE B O 1 +ATOM 7299 C CB . ILE C 1 106 ? -47.341 15.188 -127.622 1.00 54.93 ? 168 ILE B CB 1 +ATOM 7300 C CG1 . ILE C 1 106 ? -46.775 13.782 -127.461 1.00 49.65 ? 168 ILE B CG1 1 +ATOM 7301 C CG2 . ILE C 1 106 ? -48.499 15.332 -126.655 1.00 53.15 ? 168 ILE B CG2 1 +ATOM 7302 C CD1 . ILE C 1 106 ? -46.392 13.464 -126.031 1.00 48.34 ? 168 ILE B CD1 1 +ATOM 7303 N N . ASN C 1 107 ? -49.478 17.113 -129.615 1.00 60.67 ? 169 ASN B N 1 +ATOM 7304 C CA . ASN C 1 107 ? -50.032 18.422 -129.921 1.00 54.83 ? 169 ASN B CA 1 +ATOM 7305 C C . ASN C 1 107 ? -51.112 18.775 -128.903 1.00 56.47 ? 169 ASN B C 1 +ATOM 7306 O O . ASN C 1 107 ? -51.402 18.014 -127.976 1.00 57.08 ? 169 ASN B O 1 +ATOM 7307 C CB . ASN C 1 107 ? -50.583 18.448 -131.352 1.00 55.76 ? 169 ASN B CB 1 +ATOM 7308 C CG . ASN C 1 107 ? -51.450 17.235 -131.675 1.00 59.65 ? 169 ASN B CG 1 +ATOM 7309 O OD1 . ASN C 1 107 ? -51.459 16.244 -130.943 1.00 62.47 ? 169 ASN B OD1 1 +ATOM 7310 N ND2 . ASN C 1 107 ? -52.165 17.301 -132.788 1.00 60.31 ? 169 ASN B ND2 1 +ATOM 7311 N N . ARG C 1 108 ? -51.697 19.962 -129.075 1.00 57.45 ? 170 ARG B N 1 +ATOM 7312 C CA . ARG C 1 108 ? -52.780 20.402 -128.205 1.00 53.91 ? 170 ARG B CA 1 +ATOM 7313 C C . ARG C 1 108 ? -54.018 19.518 -128.320 1.00 52.35 ? 170 ARG B C 1 +ATOM 7314 O O . ARG C 1 108 ? -54.879 19.567 -127.433 1.00 49.30 ? 170 ARG B O 1 +ATOM 7315 C CB . ARG C 1 108 ? -53.118 21.864 -128.525 1.00 55.38 ? 170 ARG B CB 1 +ATOM 7316 C CG . ARG C 1 108 ? -53.982 22.564 -127.484 1.00 57.12 ? 170 ARG B CG 1 +ATOM 7317 C CD . ARG C 1 108 ? -54.132 24.050 -127.789 1.00 58.22 ? 170 ARG B CD 1 +ATOM 7318 N NE . ARG C 1 108 ? -52.846 24.747 -127.774 1.00 59.53 ? 170 ARG B NE 1 +ATOM 7319 C CZ . ARG C 1 108 ? -52.342 25.366 -126.710 1.00 59.27 ? 170 ARG B CZ 1 +ATOM 7320 N NH1 . ARG C 1 108 ? -53.015 25.374 -125.566 1.00 60.45 ? 170 ARG B NH1 1 +ATOM 7321 N NH2 . ARG C 1 108 ? -51.165 25.976 -126.786 1.00 52.27 ? 170 ARG B NH2 1 +ATOM 7322 N N . HIS C 1 109 ? -54.110 18.686 -129.357 1.00 55.70 ? 171 HIS B N 1 +ATOM 7323 C CA . HIS C 1 109 ? -55.275 17.843 -129.594 1.00 59.00 ? 171 HIS B CA 1 +ATOM 7324 C C . HIS C 1 109 ? -55.149 16.458 -128.982 1.00 51.88 ? 171 HIS B C 1 +ATOM 7325 O O . HIS C 1 109 ? -56.089 15.665 -129.093 1.00 56.59 ? 171 HIS B O 1 +ATOM 7326 C CB . HIS C 1 109 ? -55.540 17.716 -131.099 1.00 67.68 ? 171 HIS B CB 1 +ATOM 7327 C CG . HIS C 1 109 ? -56.259 18.890 -131.687 1.00 79.47 ? 171 HIS B CG 1 +ATOM 7328 N ND1 . HIS C 1 109 ? -56.490 19.019 -133.039 1.00 82.22 ? 171 HIS B ND1 1 +ATOM 7329 C CD2 . HIS C 1 109 ? -56.809 19.982 -131.103 1.00 78.45 ? 171 HIS B CD2 1 +ATOM 7330 C CE1 . HIS C 1 109 ? -57.144 20.145 -133.264 1.00 91.04 ? 171 HIS B CE1 1 +ATOM 7331 N NE2 . HIS C 1 109 ? -57.351 20.748 -132.106 1.00 87.39 ? 171 HIS B NE2 1 +ATOM 7332 N N . GLY C 1 110 ? -54.028 16.137 -128.365 1.00 48.77 ? 172 GLY B N 1 +ATOM 7333 C CA . GLY C 1 110 ? -53.911 14.870 -127.673 1.00 52.54 ? 172 GLY B CA 1 +ATOM 7334 C C . GLY C 1 110 ? -52.481 14.372 -127.657 1.00 51.56 ? 172 GLY B C 1 +ATOM 7335 O O . GLY C 1 110 ? -51.554 15.029 -128.124 1.00 50.43 ? 172 GLY B O 1 +ATOM 7336 N N . LEU C 1 111 ? -52.329 13.170 -127.099 1.00 47.56 ? 173 LEU B N 1 +ATOM 7337 C CA . LEU C 1 111 ? -51.010 12.568 -126.970 1.00 40.00 ? 173 LEU B CA 1 +ATOM 7338 C C . LEU C 1 111 ? -50.471 12.124 -128.321 1.00 43.63 ? 173 LEU B C 1 +ATOM 7339 O O . LEU C 1 111 ? -49.302 12.365 -128.635 1.00 46.35 ? 173 LEU B O 1 +ATOM 7340 C CB . LEU C 1 111 ? -51.078 11.384 -126.012 1.00 38.00 ? 173 LEU B CB 1 +ATOM 7341 C CG . LEU C 1 111 ? -50.230 11.494 -124.751 1.00 43.87 ? 173 LEU B CG 1 +ATOM 7342 C CD1 . LEU C 1 111 ? -50.451 12.835 -124.071 1.00 47.54 ? 173 LEU B CD1 1 +ATOM 7343 C CD2 . LEU C 1 111 ? -50.552 10.347 -123.807 1.00 41.44 ? 173 LEU B CD2 1 +ATOM 7344 N N . TYR C 1 112 ? -51.309 11.492 -129.137 1.00 46.29 ? 174 TYR B N 1 +ATOM 7345 C CA . TYR C 1 112 ? -50.897 10.977 -130.434 1.00 47.97 ? 174 TYR B CA 1 +ATOM 7346 C C . TYR C 1 112 ? -51.900 11.416 -131.498 1.00 50.44 ? 174 TYR B C 1 +ATOM 7347 O O . TYR C 1 112 ? -52.899 12.081 -131.209 1.00 50.72 ? 174 TYR B O 1 +ATOM 7348 C CB . TYR C 1 112 ? -50.741 9.451 -130.403 1.00 42.07 ? 174 TYR B CB 1 +ATOM 7349 C CG . TYR C 1 112 ? -51.907 8.686 -129.820 1.00 38.18 ? 174 TYR B CG 1 +ATOM 7350 C CD1 . TYR C 1 112 ? -52.120 8.639 -128.451 1.00 39.94 ? 174 TYR B CD1 1 +ATOM 7351 C CD2 . TYR C 1 112 ? -52.770 7.973 -130.639 1.00 39.98 ? 174 TYR B CD2 1 +ATOM 7352 C CE1 . TYR C 1 112 ? -53.179 7.931 -127.915 1.00 44.55 ? 174 TYR B CE1 1 +ATOM 7353 C CE2 . TYR C 1 112 ? -53.826 7.251 -130.111 1.00 44.56 ? 174 TYR B CE2 1 +ATOM 7354 C CZ . TYR C 1 112 ? -54.028 7.237 -128.747 1.00 42.45 ? 174 TYR B CZ 1 +ATOM 7355 O OH . TYR C 1 112 ? -55.079 6.528 -128.209 1.00 38.00 ? 174 TYR B OH 1 +ATOM 7356 N N . SER C 1 113 ? -51.613 11.055 -132.745 1.00 55.44 ? 175 SER B N 1 +ATOM 7357 C CA . SER C 1 113 ? -52.441 11.424 -133.883 1.00 53.82 ? 175 SER B CA 1 +ATOM 7358 C C . SER C 1 113 ? -53.494 10.354 -134.172 1.00 51.53 ? 175 SER B C 1 +ATOM 7359 O O . SER C 1 113 ? -53.353 9.185 -133.803 1.00 48.39 ? 175 SER B O 1 +ATOM 7360 C CB . SER C 1 113 ? -51.572 11.658 -135.117 1.00 54.95 ? 175 SER B CB 1 +ATOM 7361 O OG . SER C 1 113 ? -50.380 12.345 -134.772 1.00 53.91 ? 175 SER B OG 1 +ATOM 7362 N N . ARG C 1 114 ? -54.566 10.778 -134.837 1.00 47.75 ? 176 ARG B N 1 +ATOM 7363 C CA . ARG C 1 114 ? -55.638 9.861 -135.204 1.00 51.38 ? 176 ARG B CA 1 +ATOM 7364 C C . ARG C 1 114 ? -55.167 8.924 -136.311 1.00 54.55 ? 176 ARG B C 1 +ATOM 7365 O O . ARG C 1 114 ? -54.775 9.382 -137.390 1.00 56.83 ? 176 ARG B O 1 +ATOM 7366 C CB . ARG C 1 114 ? -56.871 10.649 -135.640 1.00 56.06 ? 176 ARG B CB 1 +ATOM 7367 C CG . ARG C 1 114 ? -58.066 9.786 -136.027 1.00 62.86 ? 176 ARG B CG 1 +ATOM 7368 C CD . ARG C 1 114 ? -59.373 10.460 -135.623 1.00 62.98 ? 176 ARG B CD 1 +ATOM 7369 N NE . ARG C 1 114 ? -59.524 11.786 -136.211 1.00 60.29 ? 176 ARG B NE 1 +ATOM 7370 C CZ . ARG C 1 114 ? -60.449 12.665 -135.838 1.00 59.78 ? 176 ARG B CZ 1 +ATOM 7371 N NH1 . ARG C 1 114 ? -61.304 12.365 -134.869 1.00 53.48 ? 176 ARG B NH1 1 +ATOM 7372 N NH2 . ARG C 1 114 ? -60.513 13.847 -136.433 1.00 65.60 ? 176 ARG B NH2 1 +ATOM 7373 N N . SER C 1 115 ? -55.212 7.617 -136.048 1.00 52.09 ? 177 SER B N 1 +ATOM 7374 C CA . SER C 1 115 ? -54.693 6.604 -136.970 1.00 53.41 ? 177 SER B CA 1 +ATOM 7375 C C . SER C 1 115 ? -53.281 6.965 -137.424 1.00 54.52 ? 177 SER B C 1 +ATOM 7376 O O . SER C 1 115 ? -53.013 7.191 -138.606 1.00 51.31 ? 177 SER B O 1 +ATOM 7377 C CB . SER C 1 115 ? -55.618 6.414 -138.177 1.00 55.94 ? 177 SER B CB 1 +ATOM 7378 O OG . SER C 1 115 ? -56.825 5.763 -137.826 1.00 64.30 ? 177 SER B OG 1 +ATOM 7379 N N . SER C 1 116 ? -52.378 7.050 -136.444 1.00 60.48 ? 178 SER B N 1 +ATOM 7380 C CA . SER C 1 116 ? -50.997 7.475 -136.664 1.00 58.53 ? 178 SER B CA 1 +ATOM 7381 C C . SER C 1 116 ? -50.125 6.268 -136.990 1.00 52.15 ? 178 SER B C 1 +ATOM 7382 O O . SER C 1 116 ? -50.153 5.274 -136.252 1.00 48.74 ? 178 SER B O 1 +ATOM 7383 C CB . SER C 1 116 ? -50.456 8.197 -135.431 1.00 53.05 ? 178 SER B CB 1 +ATOM 7384 O OG . SER C 1 116 ? -49.061 8.447 -135.517 1.00 49.89 ? 178 SER B OG 1 +ATOM 7385 N N . PRO C 1 117 ? -49.350 6.306 -138.080 1.00 49.17 ? 179 PRO B N 1 +ATOM 7386 C CA . PRO C 1 117 ? -48.412 5.205 -138.338 1.00 48.07 ? 179 PRO B CA 1 +ATOM 7387 C C . PRO C 1 117 ? -47.273 5.173 -137.343 1.00 54.25 ? 179 PRO B C 1 +ATOM 7388 O O . PRO C 1 117 ? -46.655 4.116 -137.162 1.00 54.58 ? 179 PRO B O 1 +ATOM 7389 C CB . PRO C 1 117 ? -47.910 5.496 -139.755 1.00 44.38 ? 179 PRO B CB 1 +ATOM 7390 C CG . PRO C 1 117 ? -48.033 6.985 -139.880 1.00 44.60 ? 179 PRO B CG 1 +ATOM 7391 C CD . PRO C 1 117 ? -49.243 7.378 -139.087 1.00 42.92 ? 179 PRO B CD 1 +ATOM 7392 N N . VAL C 1 118 ? -47.003 6.294 -136.671 1.00 55.98 ? 180 VAL B N 1 +ATOM 7393 C CA . VAL C 1 118 ? -45.981 6.322 -135.633 1.00 45.98 ? 180 VAL B CA 1 +ATOM 7394 C C . VAL C 1 118 ? -46.382 5.410 -134.486 1.00 40.82 ? 180 VAL B C 1 +ATOM 7395 O O . VAL C 1 118 ? -45.579 4.603 -134.001 1.00 39.97 ? 180 VAL B O 1 +ATOM 7396 C CB . VAL C 1 118 ? -45.756 7.769 -135.150 1.00 41.97 ? 180 VAL B CB 1 +ATOM 7397 C CG1 . VAL C 1 118 ? -44.836 7.801 -133.943 1.00 41.20 ? 180 VAL B CG1 1 +ATOM 7398 C CG2 . VAL C 1 118 ? -45.197 8.629 -136.270 1.00 42.35 ? 180 VAL B CG2 1 +ATOM 7399 N N . VAL C 1 119 ? -47.640 5.495 -134.060 1.00 38.00 ? 181 VAL B N 1 +ATOM 7400 C CA . VAL C 1 119 ? -48.082 4.707 -132.919 1.00 38.00 ? 181 VAL B CA 1 +ATOM 7401 C C . VAL C 1 119 ? -48.029 3.220 -133.233 1.00 38.00 ? 181 VAL B C 1 +ATOM 7402 O O . VAL C 1 119 ? -47.736 2.402 -132.357 1.00 43.61 ? 181 VAL B O 1 +ATOM 7403 C CB . VAL C 1 119 ? -49.482 5.154 -132.489 1.00 38.00 ? 181 VAL B CB 1 +ATOM 7404 C CG1 . VAL C 1 119 ? -49.841 4.517 -131.179 1.00 38.00 ? 181 VAL B CG1 1 +ATOM 7405 C CG2 . VAL C 1 119 ? -49.507 6.660 -132.381 1.00 38.00 ? 181 VAL B CG2 1 +ATOM 7406 N N . SER C 1 120 ? -48.327 2.842 -134.478 1.00 46.34 ? 182 SER B N 1 +ATOM 7407 C CA . SER C 1 120 ? -48.231 1.436 -134.869 1.00 48.27 ? 182 SER B CA 1 +ATOM 7408 C C . SER C 1 120 ? -46.799 0.923 -134.766 1.00 45.12 ? 182 SER B C 1 +ATOM 7409 O O . SER C 1 120 ? -46.570 -0.240 -134.407 1.00 43.87 ? 182 SER B O 1 +ATOM 7410 C CB . SER C 1 120 ? -48.765 1.245 -136.286 1.00 47.93 ? 182 SER B CB 1 +ATOM 7411 O OG . SER C 1 120 ? -50.143 1.558 -136.345 1.00 56.67 ? 182 SER B OG 1 +ATOM 7412 N N . LYS C 1 121 ? -45.824 1.759 -135.139 1.00 46.28 ? 183 LYS B N 1 +ATOM 7413 C CA . LYS C 1 121 ? -44.418 1.399 -134.978 1.00 44.39 ? 183 LYS B CA 1 +ATOM 7414 C C . LYS C 1 121 ? -44.002 1.449 -133.515 1.00 44.25 ? 183 LYS B C 1 +ATOM 7415 O O . LYS C 1 121 ? -43.264 0.577 -133.041 1.00 44.77 ? 183 LYS B O 1 +ATOM 7416 C CB . LYS C 1 121 ? -43.548 2.338 -135.813 1.00 43.49 ? 183 LYS B CB 1 +ATOM 7417 C CG . LYS C 1 121 ? -42.067 2.025 -135.809 1.00 38.00 ? 183 LYS B CG 1 +ATOM 7418 C CD . LYS C 1 121 ? -41.815 0.683 -136.473 1.00 43.58 ? 183 LYS B CD 1 +ATOM 7419 C CE . LYS C 1 121 ? -40.368 0.532 -136.905 1.00 47.12 ? 183 LYS B CE 1 +ATOM 7420 N NZ . LYS C 1 121 ? -39.418 0.840 -135.805 1.00 50.18 ? 183 LYS B NZ 1 +ATOM 7421 N N . LEU C 1 122 ? -44.483 2.460 -132.784 1.00 41.68 ? 184 LEU B N 1 +ATOM 7422 C CA . LEU C 1 122 ? -44.157 2.598 -131.370 1.00 38.00 ? 184 LEU B CA 1 +ATOM 7423 C C . LEU C 1 122 ? -44.609 1.378 -130.583 1.00 38.00 ? 184 LEU B C 1 +ATOM 7424 O O . LEU C 1 122 ? -43.874 0.866 -129.734 1.00 38.00 ? 184 LEU B O 1 +ATOM 7425 C CB . LEU C 1 122 ? -44.792 3.871 -130.814 1.00 38.00 ? 184 LEU B CB 1 +ATOM 7426 C CG . LEU C 1 122 ? -44.585 4.138 -129.327 1.00 38.00 ? 184 LEU B CG 1 +ATOM 7427 C CD1 . LEU C 1 122 ? -43.114 4.123 -129.007 1.00 38.00 ? 184 LEU B CD1 1 +ATOM 7428 C CD2 . LEU C 1 122 ? -45.188 5.475 -128.952 1.00 38.00 ? 184 LEU B CD2 1 +ATOM 7429 N N . LEU C 1 123 ? -45.827 0.906 -130.838 1.00 38.03 ? 185 LEU B N 1 +ATOM 7430 C CA . LEU C 1 123 ? -46.283 -0.306 -130.173 1.00 38.00 ? 185 LEU B CA 1 +ATOM 7431 C C . LEU C 1 123 ? -45.410 -1.493 -130.542 1.00 47.41 ? 185 LEU B C 1 +ATOM 7432 O O . LEU C 1 123 ? -45.021 -2.281 -129.672 1.00 51.52 ? 185 LEU B O 1 +ATOM 7433 C CB . LEU C 1 123 ? -47.733 -0.599 -130.535 1.00 38.00 ? 185 LEU B CB 1 +ATOM 7434 C CG . LEU C 1 123 ? -48.742 -0.067 -129.534 1.00 40.32 ? 185 LEU B CG 1 +ATOM 7435 C CD1 . LEU C 1 123 ? -49.422 1.150 -130.095 1.00 42.69 ? 185 LEU B CD1 1 +ATOM 7436 C CD2 . LEU C 1 123 ? -49.750 -1.153 -129.206 1.00 62.54 ? 185 LEU B CD2 1 +ATOM 7437 N N . GLN C 1 124 ? -45.074 -1.626 -131.827 1.00 50.63 ? 186 GLN B N 1 +ATOM 7438 C CA . GLN C 1 124 ? -44.272 -2.765 -132.253 1.00 51.99 ? 186 GLN B CA 1 +ATOM 7439 C C . GLN C 1 124 ? -42.861 -2.703 -131.692 1.00 46.61 ? 186 GLN B C 1 +ATOM 7440 O O . GLN C 1 124 ? -42.262 -3.747 -131.413 1.00 47.84 ? 186 GLN B O 1 +ATOM 7441 C CB . GLN C 1 124 ? -44.233 -2.844 -133.781 1.00 54.41 ? 186 GLN B CB 1 +ATOM 7442 C CG . GLN C 1 124 ? -45.528 -3.321 -134.412 1.00 56.58 ? 186 GLN B CG 1 +ATOM 7443 C CD . GLN C 1 124 ? -45.934 -4.702 -133.921 1.00 63.01 ? 186 GLN B CD 1 +ATOM 7444 O OE1 . GLN C 1 124 ? -47.002 -4.870 -133.324 1.00 69.83 ? 186 GLN B OE1 1 +ATOM 7445 N NE2 . GLN C 1 124 ? -45.079 -5.696 -134.162 1.00 50.36 ? 186 GLN B NE2 1 +ATOM 7446 N N . ASP C 1 125 ? -42.328 -1.500 -131.488 1.00 46.57 ? 187 ASP B N 1 +ATOM 7447 C CA . ASP C 1 125 ? -40.969 -1.385 -130.971 1.00 50.58 ? 187 ASP B CA 1 +ATOM 7448 C C . ASP C 1 125 ? -40.898 -1.783 -129.502 1.00 44.09 ? 187 ASP B C 1 +ATOM 7449 O O . ASP C 1 125 ? -40.028 -2.564 -129.104 1.00 42.05 ? 187 ASP B O 1 +ATOM 7450 C CB . ASP C 1 125 ? -40.445 0.032 -131.187 1.00 51.00 ? 187 ASP B CB 1 +ATOM 7451 C CG . ASP C 1 125 ? -40.095 0.297 -132.633 1.00 44.81 ? 187 ASP B CG 1 +ATOM 7452 O OD1 . ASP C 1 125 ? -40.349 -0.599 -133.465 1.00 41.58 ? 187 ASP B OD1 1 +ATOM 7453 O OD2 . ASP C 1 125 ? -39.544 1.377 -132.933 1.00 51.29 ? 187 ASP B OD2 1 +ATOM 7454 N N . MET C 1 126 ? -41.818 -1.277 -128.683 1.00 38.00 ? 188 MET B N 1 +ATOM 7455 C CA . MET C 1 126 ? -41.804 -1.654 -127.278 1.00 38.00 ? 188 MET B CA 1 +ATOM 7456 C C . MET C 1 126 ? -42.033 -3.146 -127.098 1.00 42.21 ? 188 MET B C 1 +ATOM 7457 O O . MET C 1 126 ? -41.652 -3.701 -126.061 1.00 41.43 ? 188 MET B O 1 +ATOM 7458 C CB . MET C 1 126 ? -42.866 -0.871 -126.510 1.00 38.00 ? 188 MET B CB 1 +ATOM 7459 C CG . MET C 1 126 ? -42.771 0.629 -126.694 1.00 38.43 ? 188 MET B CG 1 +ATOM 7460 S SD . MET C 1 126 ? -43.691 1.540 -125.452 1.00 38.00 ? 188 MET B SD 1 +ATOM 7461 C CE . MET C 1 126 ? -45.356 1.372 -126.061 1.00 38.00 ? 188 MET B CE 1 +ATOM 7462 N N . ARG C 1 127 ? -42.591 -3.819 -128.107 1.00 38.00 ? 189 ARG B N 1 +ATOM 7463 C CA . ARG C 1 127 ? -42.842 -5.246 -127.976 1.00 38.00 ? 189 ARG B CA 1 +ATOM 7464 C C . ARG C 1 127 ? -41.608 -6.069 -128.307 1.00 39.24 ? 189 ARG B C 1 +ATOM 7465 O O . ARG C 1 127 ? -41.424 -7.147 -127.735 1.00 40.51 ? 189 ARG B O 1 +ATOM 7466 C CB . ARG C 1 127 ? -44.003 -5.673 -128.880 1.00 44.08 ? 189 ARG B CB 1 +ATOM 7467 C CG . ARG C 1 127 ? -44.581 -7.049 -128.540 1.00 52.49 ? 189 ARG B CG 1 +ATOM 7468 C CD . ARG C 1 127 ? -45.133 -7.783 -129.767 1.00 54.69 ? 189 ARG B CD 1 +ATOM 7469 N NE . ARG C 1 127 ? -45.952 -6.919 -130.613 1.00 65.33 ? 189 ARG B NE 1 +ATOM 7470 C CZ . ARG C 1 127 ? -47.220 -6.605 -130.358 1.00 67.73 ? 189 ARG B CZ 1 +ATOM 7471 N NH1 . ARG C 1 127 ? -47.812 -7.085 -129.273 1.00 73.51 ? 189 ARG B NH1 1 +ATOM 7472 N NH2 . ARG C 1 127 ? -47.895 -5.808 -131.182 1.00 57.86 ? 189 ARG B NH2 1 +ATOM 7473 N N . HIS C 1 128 ? -40.738 -5.579 -129.190 1.00 40.94 ? 190 HIS B N 1 +ATOM 7474 C CA . HIS C 1 128 ? -39.648 -6.399 -129.702 1.00 47.11 ? 190 HIS B CA 1 +ATOM 7475 C C . HIS C 1 128 ? -38.255 -5.881 -129.374 1.00 43.59 ? 190 HIS B C 1 +ATOM 7476 O O . HIS C 1 128 ? -37.342 -6.694 -129.211 1.00 50.94 ? 190 HIS B O 1 +ATOM 7477 C CB . HIS C 1 128 ? -39.773 -6.564 -131.226 1.00 46.95 ? 190 HIS B CB 1 +ATOM 7478 C CG . HIS C 1 128 ? -41.051 -7.215 -131.653 1.00 53.12 ? 190 HIS B CG 1 +ATOM 7479 N ND1 . HIS C 1 128 ? -41.189 -8.582 -131.751 1.00 62.85 ? 190 HIS B ND1 1 +ATOM 7480 C CD2 . HIS C 1 128 ? -42.244 -6.689 -132.018 1.00 52.85 ? 190 HIS B CD2 1 +ATOM 7481 C CE1 . HIS C 1 128 ? -42.417 -8.872 -132.144 1.00 67.69 ? 190 HIS B CE1 1 +ATOM 7482 N NE2 . HIS C 1 128 ? -43.076 -7.740 -132.318 1.00 60.63 ? 190 HIS B NE2 1 +ATOM 7483 N N . PHE C 1 129 ? -38.067 -4.571 -129.261 1.00 38.00 ? 191 PHE B N 1 +ATOM 7484 C CA . PHE C 1 129 ? -36.738 -4.030 -129.021 1.00 38.00 ? 191 PHE B CA 1 +ATOM 7485 C C . PHE C 1 129 ? -36.160 -4.606 -127.734 1.00 40.43 ? 191 PHE B C 1 +ATOM 7486 O O . PHE C 1 129 ? -36.891 -4.795 -126.754 1.00 45.15 ? 191 PHE B O 1 +ATOM 7487 C CB . PHE C 1 129 ? -36.789 -2.509 -128.927 1.00 38.00 ? 191 PHE B CB 1 +ATOM 7488 C CG . PHE C 1 129 ? -36.712 -1.821 -130.249 1.00 39.37 ? 191 PHE B CG 1 +ATOM 7489 C CD1 . PHE C 1 129 ? -37.536 -2.202 -131.291 1.00 47.06 ? 191 PHE B CD1 1 +ATOM 7490 C CD2 . PHE C 1 129 ? -35.838 -0.767 -130.443 1.00 39.07 ? 191 PHE B CD2 1 +ATOM 7491 C CE1 . PHE C 1 129 ? -37.475 -1.564 -132.506 1.00 42.40 ? 191 PHE B CE1 1 +ATOM 7492 C CE2 . PHE C 1 129 ? -35.776 -0.120 -131.654 1.00 42.24 ? 191 PHE B CE2 1 +ATOM 7493 C CZ . PHE C 1 129 ? -36.597 -0.516 -132.687 1.00 44.10 ? 191 PHE B CZ 1 +ATOM 7494 N N . PRO C 1 130 ? -34.869 -4.913 -127.702 1.00 44.09 ? 192 PRO B N 1 +ATOM 7495 C CA . PRO C 1 130 ? -34.276 -5.450 -126.477 1.00 52.28 ? 192 PRO B CA 1 +ATOM 7496 C C . PRO C 1 130 ? -34.103 -4.358 -125.432 1.00 46.45 ? 192 PRO B C 1 +ATOM 7497 O O . PRO C 1 130 ? -34.002 -3.167 -125.738 1.00 42.58 ? 192 PRO B O 1 +ATOM 7498 C CB . PRO C 1 130 ? -32.922 -5.989 -126.950 1.00 46.72 ? 192 PRO B CB 1 +ATOM 7499 C CG . PRO C 1 130 ? -32.567 -5.090 -128.088 1.00 38.00 ? 192 PRO B CG 1 +ATOM 7500 C CD . PRO C 1 130 ? -33.871 -4.756 -128.773 1.00 41.39 ? 192 PRO B CD 1 +ATOM 7501 N N . THR C 1 131 ? -34.079 -4.785 -124.175 1.00 40.32 ? 193 THR B N 1 +ATOM 7502 C CA . THR C 1 131 ? -33.883 -3.872 -123.064 1.00 38.00 ? 193 THR B CA 1 +ATOM 7503 C C . THR C 1 131 ? -32.398 -3.696 -122.794 1.00 38.08 ? 193 THR B C 1 +ATOM 7504 O O . THR C 1 131 ? -31.612 -4.639 -122.922 1.00 39.40 ? 193 THR B O 1 +ATOM 7505 C CB . THR C 1 131 ? -34.579 -4.383 -121.808 1.00 38.00 ? 193 THR B CB 1 +ATOM 7506 O OG1 . THR C 1 131 ? -34.144 -5.718 -121.537 1.00 38.00 ? 193 THR B OG1 1 +ATOM 7507 C CG2 . THR C 1 131 ? -36.070 -4.374 -122.010 1.00 38.00 ? 193 THR B CG2 1 +ATOM 7508 N N . ILE C 1 132 ? -32.017 -2.476 -122.434 1.00 38.00 ? 194 ILE B N 1 +ATOM 7509 C CA . ILE C 1 132 ? -30.628 -2.157 -122.133 1.00 38.00 ? 194 ILE B CA 1 +ATOM 7510 C C . ILE C 1 132 ? -30.426 -1.679 -120.707 1.00 38.00 ? 194 ILE B C 1 +ATOM 7511 O O . ILE C 1 132 ? -29.271 -1.501 -120.293 1.00 38.00 ? 194 ILE B O 1 +ATOM 7512 C CB . ILE C 1 132 ? -30.072 -1.109 -123.116 1.00 38.00 ? 194 ILE B CB 1 +ATOM 7513 C CG1 . ILE C 1 132 ? -30.738 0.243 -122.875 1.00 38.00 ? 194 ILE B CG1 1 +ATOM 7514 C CG2 . ILE C 1 132 ? -30.318 -1.542 -124.546 1.00 45.97 ? 194 ILE B CG2 1 +ATOM 7515 C CD1 . ILE C 1 132 ? -30.259 1.310 -123.816 1.00 38.00 ? 194 ILE B CD1 1 +ATOM 7516 N N . SER C 1 133 ? -31.495 -1.482 -119.940 1.00 38.00 ? 195 SER B N 1 +ATOM 7517 C CA . SER C 1 133 ? -31.426 -0.863 -118.626 1.00 38.00 ? 195 SER B CA 1 +ATOM 7518 C C . SER C 1 133 ? -32.766 -1.040 -117.922 1.00 39.62 ? 195 SER B C 1 +ATOM 7519 O O . SER C 1 133 ? -33.819 -1.013 -118.563 1.00 45.10 ? 195 SER B O 1 +ATOM 7520 C CB . SER C 1 133 ? -31.067 0.627 -118.776 1.00 38.00 ? 195 SER B CB 1 +ATOM 7521 O OG . SER C 1 133 ? -31.543 1.438 -117.716 1.00 50.07 ? 195 SER B OG 1 +ATOM 7522 N N . ALA C 1 134 ? -32.716 -1.190 -116.597 1.00 38.00 ? 196 ALA B N 1 +ATOM 7523 C CA . ALA C 1 134 ? -33.921 -1.279 -115.778 1.00 38.00 ? 196 ALA B CA 1 +ATOM 7524 C C . ALA C 1 134 ? -33.627 -0.667 -114.418 1.00 38.00 ? 196 ALA B C 1 +ATOM 7525 O O . ALA C 1 134 ? -32.579 -0.946 -113.828 1.00 38.00 ? 196 ALA B O 1 +ATOM 7526 C CB . ALA C 1 134 ? -34.399 -2.726 -115.622 1.00 38.00 ? 196 ALA B CB 1 +ATOM 7527 N N . ASP C 1 135 ? -34.539 0.181 -113.940 1.00 38.00 ? 197 ASP B N 1 +ATOM 7528 C CA . ASP C 1 135 ? -34.389 0.828 -112.642 1.00 38.00 ? 197 ASP B CA 1 +ATOM 7529 C C . ASP C 1 135 ? -35.688 0.758 -111.843 1.00 39.22 ? 197 ASP B C 1 +ATOM 7530 O O . ASP C 1 135 ? -36.652 0.109 -112.262 1.00 39.37 ? 197 ASP B O 1 +ATOM 7531 C CB . ASP C 1 135 ? -33.950 2.283 -112.825 1.00 45.72 ? 197 ASP B CB 1 +ATOM 7532 C CG . ASP C 1 135 ? -33.214 2.834 -111.613 1.00 51.38 ? 197 ASP B CG 1 +ATOM 7533 O OD1 . ASP C 1 135 ? -33.503 2.386 -110.484 1.00 48.99 ? 197 ASP B OD1 1 +ATOM 7534 O OD2 . ASP C 1 135 ? -32.347 3.718 -111.789 1.00 58.53 ? 197 ASP B OD2 1 +ATOM 7535 N N . TYR C 1 136 ? -35.739 1.466 -110.716 1.00 44.98 ? 198 TYR B N 1 +ATOM 7536 C CA . TYR C 1 136 ? -36.891 1.451 -109.825 1.00 46.83 ? 198 TYR B CA 1 +ATOM 7537 C C . TYR C 1 136 ? -37.864 2.582 -110.098 1.00 44.84 ? 198 TYR B C 1 +ATOM 7538 O O . TYR C 1 136 ? -38.925 2.629 -109.466 1.00 42.83 ? 198 TYR B O 1 +ATOM 7539 C CB . TYR C 1 136 ? -36.422 1.531 -108.365 1.00 47.81 ? 198 TYR B CB 1 +ATOM 7540 C CG . TYR C 1 136 ? -36.446 0.219 -107.610 1.00 44.97 ? 198 TYR B CG 1 +ATOM 7541 C CD1 . TYR C 1 136 ? -37.552 -0.616 -107.662 1.00 43.54 ? 198 TYR B CD1 1 +ATOM 7542 C CD2 . TYR C 1 136 ? -35.360 -0.184 -106.845 1.00 47.73 ? 198 TYR B CD2 1 +ATOM 7543 C CE1 . TYR C 1 136 ? -37.580 -1.814 -106.971 1.00 44.98 ? 198 TYR B CE1 1 +ATOM 7544 C CE2 . TYR C 1 136 ? -35.377 -1.386 -106.153 1.00 47.79 ? 198 TYR B CE2 1 +ATOM 7545 C CZ . TYR C 1 136 ? -36.492 -2.196 -106.221 1.00 47.41 ? 198 TYR B CZ 1 +ATOM 7546 O OH . TYR C 1 136 ? -36.530 -3.392 -105.540 1.00 51.40 ? 198 TYR B OH 1 +ATOM 7547 N N . SER C 1 137 ? -37.536 3.475 -111.033 1.00 46.93 ? 199 SER B N 1 +ATOM 7548 C CA . SER C 1 137 ? -38.324 4.664 -111.342 1.00 55.03 ? 199 SER B CA 1 +ATOM 7549 C C . SER C 1 137 ? -38.317 5.659 -110.192 1.00 59.99 ? 199 SER B C 1 +ATOM 7550 O O . SER C 1 137 ? -37.990 5.314 -109.052 1.00 63.62 ? 199 SER B O 1 +ATOM 7551 C CB . SER C 1 137 ? -39.773 4.297 -111.687 1.00 61.36 ? 199 SER B CB 1 +ATOM 7552 O OG . SER C 1 137 ? -40.519 3.998 -110.514 1.00 45.18 ? 199 SER B OG 1 +ATOM 7553 N N . GLN C 1 138 ? -38.707 6.895 -110.479 1.00 57.90 ? 200 GLN B N 1 +ATOM 7554 C CA . GLN C 1 138 ? -38.928 7.878 -109.432 1.00 55.61 ? 200 GLN B CA 1 +ATOM 7555 C C . GLN C 1 138 ? -40.225 7.531 -108.716 1.00 54.02 ? 200 GLN B C 1 +ATOM 7556 O O . GLN C 1 138 ? -40.701 6.398 -108.822 1.00 60.80 ? 200 GLN B O 1 +ATOM 7557 C CB . GLN C 1 138 ? -38.988 9.276 -110.033 1.00 65.83 ? 200 GLN B CB 1 +ATOM 7558 C CG . GLN C 1 138 ? -38.289 10.315 -109.213 1.00 75.93 ? 200 GLN B CG 1 +ATOM 7559 C CD . GLN C 1 138 ? -36.807 10.398 -109.512 1.00 75.73 ? 200 GLN B CD 1 +ATOM 7560 O OE1 . GLN C 1 138 ? -36.116 11.267 -108.980 1.00 83.19 ? 200 GLN B OE1 1 +ATOM 7561 N NE2 . GLN C 1 138 ? -36.310 9.501 -110.365 1.00 57.54 ? 200 GLN B NE2 1 +ATOM 7562 N N . ASP C 1 139 ? -40.797 8.477 -107.973 1.00 48.54 ? 201 ASP B N 1 +ATOM 7563 C CA . ASP C 1 139 ? -42.073 8.274 -107.285 1.00 58.45 ? 201 ASP B CA 1 +ATOM 7564 C C . ASP C 1 139 ? -41.947 7.192 -106.210 1.00 63.04 ? 201 ASP B C 1 +ATOM 7565 O O . ASP C 1 139 ? -42.423 7.375 -105.083 1.00 67.69 ? 201 ASP B O 1 +ATOM 7566 C CB . ASP C 1 139 ? -43.184 8.000 -108.326 1.00 57.13 ? 201 ASP B CB 1 +ATOM 7567 C CG . ASP C 1 139 ? -43.827 6.623 -108.204 1.00 55.91 ? 201 ASP B CG 1 +ATOM 7568 O OD1 . ASP C 1 139 ? -44.687 6.439 -107.317 1.00 67.41 ? 201 ASP B OD1 1 +ATOM 7569 O OD2 . ASP C 1 139 ? -43.515 5.741 -109.035 1.00 50.57 ? 201 ASP B OD2 1 +ATOM 7570 N N . GLU C 1 140 ? -41.300 6.075 -106.528 1.00 59.72 ? 202 GLU B N 1 +ATOM 7571 C CA . GLU C 1 140 ? -40.570 5.325 -105.519 1.00 48.47 ? 202 GLU B CA 1 +ATOM 7572 C C . GLU C 1 140 ? -39.185 5.965 -105.448 1.00 53.49 ? 202 GLU B C 1 +ATOM 7573 O O . GLU C 1 140 ? -39.004 7.095 -105.911 1.00 57.93 ? 202 GLU B O 1 +ATOM 7574 C CB . GLU C 1 140 ? -40.524 3.835 -105.868 1.00 48.82 ? 202 GLU B CB 1 +ATOM 7575 C CG . GLU C 1 140 ? -40.117 2.935 -104.700 1.00 61.47 ? 202 GLU B CG 1 +ATOM 7576 C CD . GLU C 1 140 ? -38.732 2.327 -104.875 1.00 68.34 ? 202 GLU B CD 1 +ATOM 7577 O OE1 . GLU C 1 140 ? -38.448 1.802 -105.971 1.00 69.69 ? 202 GLU B OE1 1 +ATOM 7578 O OE2 . GLU C 1 140 ? -37.928 2.373 -103.917 1.00 65.79 ? 202 GLU B OE2 1 +ATOM 7579 N N . LYS C 1 141 ? -38.191 5.256 -104.913 1.00 50.81 ? 203 LYS B N 1 +ATOM 7580 C CA . LYS C 1 141 ? -36.818 5.745 -104.894 1.00 58.27 ? 203 LYS B CA 1 +ATOM 7581 C C . LYS C 1 141 ? -36.712 7.008 -104.048 1.00 50.55 ? 203 LYS B C 1 +ATOM 7582 O O . LYS C 1 141 ? -35.888 7.085 -103.131 1.00 45.44 ? 203 LYS B O 1 +ATOM 7583 C CB . LYS C 1 141 ? -36.341 6.003 -106.329 1.00 58.33 ? 203 LYS B CB 1 +ATOM 7584 C CG . LYS C 1 141 ? -34.870 5.780 -106.577 1.00 56.92 ? 203 LYS B CG 1 +ATOM 7585 C CD . LYS C 1 141 ? -34.614 5.547 -108.053 1.00 53.58 ? 203 LYS B CD 1 +ATOM 7586 C CE . LYS C 1 141 ? -33.158 5.759 -108.400 1.00 50.05 ? 203 LYS B CE 1 +ATOM 7587 N NZ . LYS C 1 141 ? -32.859 5.361 -109.801 1.00 51.96 ? 203 LYS B NZ 1 +ATOM 7588 N N . ALA C 1 142 ? -37.549 8.000 -104.354 1.00 49.91 ? 204 ALA B N 1 +ATOM 7589 C CA . ALA C 1 142 ? -37.670 9.193 -103.532 1.00 49.41 ? 204 ALA B CA 1 +ATOM 7590 C C . ALA C 1 142 ? -38.395 8.924 -102.224 1.00 45.71 ? 204 ALA B C 1 +ATOM 7591 O O . ALA C 1 142 ? -38.492 9.832 -101.393 1.00 48.72 ? 204 ALA B O 1 +ATOM 7592 C CB . ALA C 1 142 ? -38.392 10.298 -104.305 1.00 69.93 ? 204 ALA B CB 1 +ATOM 7593 N N . LEU C 1 143 ? -38.916 7.714 -102.023 1.00 41.79 ? 205 LEU B N 1 +ATOM 7594 C CA . LEU C 1 143 ? -39.443 7.381 -100.710 1.00 38.95 ? 205 LEU B CA 1 +ATOM 7595 C C . LEU C 1 143 ? -38.328 7.200 -99.693 1.00 41.04 ? 205 LEU B C 1 +ATOM 7596 O O . LEU C 1 143 ? -38.595 7.249 -98.489 1.00 51.32 ? 205 LEU B O 1 +ATOM 7597 C CB . LEU C 1 143 ? -40.297 6.117 -100.770 1.00 38.00 ? 205 LEU B CB 1 +ATOM 7598 C CG . LEU C 1 143 ? -41.633 6.265 -101.492 1.00 44.56 ? 205 LEU B CG 1 +ATOM 7599 C CD1 . LEU C 1 143 ? -42.486 5.028 -101.290 1.00 46.59 ? 205 LEU B CD1 1 +ATOM 7600 C CD2 . LEU C 1 143 ? -42.361 7.507 -101.035 1.00 51.64 ? 205 LEU B CD2 1 +ATOM 7601 N N . LEU C 1 144 ? -37.093 6.986 -100.157 1.00 39.35 ? 206 LEU B N 1 +ATOM 7602 C CA . LEU C 1 144 ? -35.916 6.856 -99.306 1.00 38.00 ? 206 LEU B CA 1 +ATOM 7603 C C . LEU C 1 144 ? -36.044 5.634 -98.410 1.00 38.00 ? 206 LEU B C 1 +ATOM 7604 O O . LEU C 1 144 ? -35.320 4.650 -98.585 1.00 38.00 ? 206 LEU B O 1 +ATOM 7605 C CB . LEU C 1 144 ? -35.707 8.119 -98.468 1.00 38.16 ? 206 LEU B CB 1 +ATOM 7606 C CG . LEU C 1 144 ? -35.336 9.377 -99.253 1.00 39.83 ? 206 LEU B CG 1 +ATOM 7607 C CD1 . LEU C 1 144 ? -34.891 10.494 -98.316 1.00 51.66 ? 206 LEU B CD1 1 +ATOM 7608 C CD2 . LEU C 1 144 ? -34.263 9.073 -100.272 1.00 41.43 ? 206 LEU B CD2 1 +ATOM 7609 N N . GLY C 1 145 ? -36.968 5.691 -97.453 1.00 38.76 ? 207 GLY B N 1 +ATOM 7610 C CA . GLY C 1 145 ? -37.237 4.572 -96.573 1.00 39.31 ? 207 GLY B CA 1 +ATOM 7611 C C . GLY C 1 145 ? -37.918 3.447 -97.320 1.00 38.00 ? 207 GLY B C 1 +ATOM 7612 O O . GLY C 1 145 ? -37.249 2.729 -98.068 1.00 38.00 ? 207 GLY B O 1 +ATOM 7613 N N . ALA C 1 146 ? -39.228 3.270 -97.157 1.00 38.00 ? 208 ALA B N 1 +ATOM 7614 C CA . ALA C 1 146 ? -40.079 4.012 -96.235 1.00 38.00 ? 208 ALA B CA 1 +ATOM 7615 C C . ALA C 1 146 ? -41.319 3.170 -96.024 1.00 43.31 ? 208 ALA B C 1 +ATOM 7616 O O . ALA C 1 146 ? -42.373 3.481 -96.569 1.00 46.26 ? 208 ALA B O 1 +ATOM 7617 C CB . ALA C 1 146 ? -40.461 5.373 -96.783 1.00 38.00 ? 208 ALA B CB 1 +ATOM 7618 N N . CYS C 1 147 ? -41.191 2.090 -95.266 1.00 48.19 ? 209 CYS B N 1 +ATOM 7619 C CA . CYS C 1 147 ? -42.245 1.093 -95.136 1.00 50.66 ? 209 CYS B CA 1 +ATOM 7620 C C . CYS C 1 147 ? -42.898 1.233 -93.761 1.00 57.34 ? 209 CYS B C 1 +ATOM 7621 O O . CYS C 1 147 ? -42.247 1.011 -92.735 1.00 61.00 ? 209 CYS B O 1 +ATOM 7622 C CB . CYS C 1 147 ? -41.670 -0.305 -95.336 1.00 49.86 ? 209 CYS B CB 1 +ATOM 7623 S SG . CYS C 1 147 ? -42.785 -1.473 -96.137 1.00 98.41 ? 209 CYS B SG 1 +ATOM 7624 N N . ASP C 1 148 ? -44.178 1.607 -93.741 1.00 59.75 ? 210 ASP B N 1 +ATOM 7625 C CA . ASP C 1 148 ? -44.982 1.687 -92.517 1.00 62.39 ? 210 ASP B CA 1 +ATOM 7626 C C . ASP C 1 148 ? -46.117 0.676 -92.649 1.00 56.49 ? 210 ASP B C 1 +ATOM 7627 O O . ASP C 1 148 ? -47.167 0.981 -93.229 1.00 59.54 ? 210 ASP B O 1 +ATOM 7628 C CB . ASP C 1 148 ? -45.525 3.103 -92.290 1.00 66.93 ? 210 ASP B CB 1 +ATOM 7629 C CG . ASP C 1 148 ? -46.209 3.274 -90.923 1.00 72.21 ? 210 ASP B CG 1 +ATOM 7630 O OD1 . ASP C 1 148 ? -46.183 2.331 -90.099 1.00 77.44 ? 210 ASP B OD1 1 +ATOM 7631 O OD2 . ASP C 1 148 ? -46.792 4.355 -90.679 1.00 64.60 ? 210 ASP B OD2 1 +ATOM 7632 N N . CYS C 1 149 ? -45.923 -0.524 -92.101 1.00 48.62 ? 211 CYS B N 1 +ATOM 7633 C CA . CYS C 1 149 ? -46.938 -1.562 -92.243 1.00 53.23 ? 211 CYS B CA 1 +ATOM 7634 C C . CYS C 1 149 ? -48.274 -1.185 -91.618 1.00 52.57 ? 211 CYS B C 1 +ATOM 7635 O O . CYS C 1 149 ? -49.277 -1.843 -91.907 1.00 52.23 ? 211 CYS B O 1 +ATOM 7636 C CB . CYS C 1 149 ? -46.417 -2.875 -91.650 1.00 70.52 ? 211 CYS B CB 1 +ATOM 7637 S SG . CYS C 1 149 ? -44.948 -3.557 -92.494 1.00 98.55 ? 211 CYS B SG 1 +ATOM 7638 N N . THR C 1 150 ? -48.326 -0.127 -90.810 1.00 57.38 ? 212 THR B N 1 +ATOM 7639 C CA . THR C 1 150 ? -49.597 0.340 -90.267 1.00 61.65 ? 212 THR B CA 1 +ATOM 7640 C C . THR C 1 150 ? -50.383 1.156 -91.286 1.00 64.70 ? 212 THR B C 1 +ATOM 7641 O O . THR C 1 150 ? -51.621 1.125 -91.288 1.00 66.20 ? 212 THR B O 1 +ATOM 7642 C CB . THR C 1 150 ? -49.335 1.156 -89.001 1.00 64.48 ? 212 THR B CB 1 +ATOM 7643 O OG1 . THR C 1 150 ? -48.866 0.276 -87.975 1.00 71.65 ? 212 THR B OG1 1 +ATOM 7644 C CG2 . THR C 1 150 ? -50.597 1.854 -88.524 1.00 70.83 ? 212 THR B CG2 1 +ATOM 7645 N N . GLN C 1 151 ? -49.687 1.879 -92.155 1.00 64.94 ? 213 GLN B N 1 +ATOM 7646 C CA . GLN C 1 151 ? -50.339 2.631 -93.216 1.00 64.83 ? 213 GLN B CA 1 +ATOM 7647 C C . GLN C 1 151 ? -51.157 1.700 -94.101 1.00 60.19 ? 213 GLN B C 1 +ATOM 7648 O O . GLN C 1 151 ? -50.613 0.797 -94.744 1.00 54.83 ? 213 GLN B O 1 +ATOM 7649 C CB . GLN C 1 151 ? -49.284 3.367 -94.036 1.00 59.66 ? 213 GLN B CB 1 +ATOM 7650 C CG . GLN C 1 151 ? -49.724 4.700 -94.589 1.00 57.08 ? 213 GLN B CG 1 +ATOM 7651 C CD . GLN C 1 151 ? -48.577 5.433 -95.246 1.00 58.28 ? 213 GLN B CD 1 +ATOM 7652 O OE1 . GLN C 1 151 ? -47.478 4.888 -95.382 1.00 49.89 ? 213 GLN B OE1 1 +ATOM 7653 N NE2 . GLN C 1 151 ? -48.822 6.674 -95.658 1.00 61.62 ? 213 GLN B NE2 1 +ATOM 7654 N N . ILE C 1 152 ? -52.472 1.913 -94.119 1.00 64.25 ? 214 ILE B N 1 +ATOM 7655 C CA . ILE C 1 152 ? -53.339 1.080 -94.943 1.00 61.02 ? 214 ILE B CA 1 +ATOM 7656 C C . ILE C 1 152 ? -53.272 1.518 -96.398 1.00 55.40 ? 214 ILE B C 1 +ATOM 7657 O O . ILE C 1 152 ? -53.230 0.685 -97.308 1.00 52.69 ? 214 ILE B O 1 +ATOM 7658 C CB . ILE C 1 152 ? -54.778 1.109 -94.401 1.00 61.91 ? 214 ILE B CB 1 +ATOM 7659 C CG1 . ILE C 1 152 ? -54.801 0.594 -92.965 1.00 55.06 ? 214 ILE B CG1 1 +ATOM 7660 C CG2 . ILE C 1 152 ? -55.698 0.269 -95.277 1.00 55.02 ? 214 ILE B CG2 1 +ATOM 7661 C CD1 . ILE C 1 152 ? -56.168 0.603 -92.350 1.00 64.25 ? 214 ILE B CD1 1 +ATOM 7662 N N . VAL C 1 153 ? -53.265 2.826 -96.642 1.00 51.07 ? 215 VAL B N 1 +ATOM 7663 C CA . VAL C 1 153 ? -53.144 3.346 -97.997 1.00 47.38 ? 215 VAL B CA 1 +ATOM 7664 C C . VAL C 1 153 ? -51.760 3.955 -98.164 1.00 52.16 ? 215 VAL B C 1 +ATOM 7665 O O . VAL C 1 153 ? -51.602 5.181 -98.199 1.00 52.60 ? 215 VAL B O 1 +ATOM 7666 C CB . VAL C 1 153 ? -54.248 4.369 -98.306 1.00 46.04 ? 215 VAL B CB 1 +ATOM 7667 C CG1 . VAL C 1 153 ? -54.311 4.629 -99.790 1.00 46.29 ? 215 VAL B CG1 1 +ATOM 7668 C CG2 . VAL C 1 153 ? -55.581 3.857 -97.802 1.00 50.54 ? 215 VAL B CG2 1 +ATOM 7669 N N . LYS C 1 154 ? -50.752 3.094 -98.247 1.00 54.92 ? 216 LYS B N 1 +ATOM 7670 C CA . LYS C 1 154 ? -49.388 3.529 -98.501 1.00 52.00 ? 216 LYS B CA 1 +ATOM 7671 C C . LYS C 1 154 ? -49.292 4.216 -99.865 1.00 47.89 ? 216 LYS B C 1 +ATOM 7672 O O . LYS C 1 154 ? -50.120 3.973 -100.751 1.00 46.61 ? 216 LYS B O 1 +ATOM 7673 C CB . LYS C 1 154 ? -48.442 2.331 -98.420 1.00 47.24 ? 216 LYS B CB 1 +ATOM 7674 C CG . LYS C 1 154 ? -49.126 0.988 -98.627 1.00 45.00 ? 216 LYS B CG 1 +ATOM 7675 C CD . LYS C 1 154 ? -48.183 -0.163 -98.323 1.00 47.06 ? 216 LYS B CD 1 +ATOM 7676 C CE . LYS C 1 154 ? -47.929 -0.306 -96.835 1.00 38.13 ? 216 LYS B CE 1 +ATOM 7677 N NZ . LYS C 1 154 ? -49.090 -0.932 -96.153 1.00 43.89 ? 216 LYS B NZ 1 +ATOM 7678 N N . PRO C 1 155 ? -48.307 5.100 -100.055 1.00 45.04 ? 217 PRO B N 1 +ATOM 7679 C CA . PRO C 1 155 ? -48.260 5.907 -101.280 1.00 53.84 ? 217 PRO B CA 1 +ATOM 7680 C C . PRO C 1 155 ? -48.141 5.048 -102.530 1.00 58.94 ? 217 PRO B C 1 +ATOM 7681 O O . PRO C 1 155 ? -47.765 3.876 -102.478 1.00 61.91 ? 217 PRO B O 1 +ATOM 7682 C CB . PRO C 1 155 ? -47.007 6.770 -101.088 1.00 51.57 ? 217 PRO B CB 1 +ATOM 7683 C CG . PRO C 1 155 ? -46.169 6.005 -100.120 1.00 38.27 ? 217 PRO B CG 1 +ATOM 7684 C CD . PRO C 1 155 ? -47.148 5.368 -99.187 1.00 41.46 ? 217 PRO B CD 1 +ATOM 7685 N N . SER C 1 156 ? -48.441 5.662 -103.677 1.00 63.54 ? 218 SER B N 1 +ATOM 7686 C CA . SER C 1 156 ? -48.437 4.939 -104.943 1.00 70.91 ? 218 SER B CA 1 +ATOM 7687 C C . SER C 1 156 ? -47.006 4.666 -105.392 1.00 63.33 ? 218 SER B C 1 +ATOM 7688 O O . SER C 1 156 ? -46.761 4.387 -106.569 1.00 74.63 ? 218 SER B O 1 +ATOM 7689 C CB . SER C 1 156 ? -49.205 5.721 -106.019 1.00 76.50 ? 218 SER B CB 1 +ATOM 7690 O OG . SER C 1 156 ? -49.302 4.992 -107.236 1.00 80.83 ? 218 SER B OG 1 +ATOM 7691 N N . GLY C 1 157 ? -46.059 4.716 -104.463 1.00 50.57 ? 219 GLY B N 1 +ATOM 7692 C CA . GLY C 1 157 ? -44.685 4.456 -104.820 1.00 49.68 ? 219 GLY B CA 1 +ATOM 7693 C C . GLY C 1 157 ? -44.240 3.077 -104.399 1.00 54.93 ? 219 GLY B C 1 +ATOM 7694 O O . GLY C 1 157 ? -43.232 2.574 -104.896 1.00 65.41 ? 219 GLY B O 1 +ATOM 7695 N N . VAL C 1 158 ? -45.015 2.418 -103.544 1.00 55.51 ? 220 VAL B N 1 +ATOM 7696 C CA . VAL C 1 158 ? -44.641 1.086 -103.083 1.00 51.09 ? 220 VAL B CA 1 +ATOM 7697 C C . VAL C 1 158 ? -45.394 0.049 -103.895 1.00 54.34 ? 220 VAL B C 1 +ATOM 7698 O O . VAL C 1 158 ? -45.927 -0.916 -103.344 1.00 65.06 ? 220 VAL B O 1 +ATOM 7699 C CB . VAL C 1 158 ? -44.915 0.899 -101.580 1.00 47.55 ? 220 VAL B CB 1 +ATOM 7700 C CG1 . VAL C 1 158 ? -43.928 1.701 -100.768 1.00 60.32 ? 220 VAL B CG1 1 +ATOM 7701 C CG2 . VAL C 1 158 ? -46.334 1.307 -101.246 1.00 48.55 ? 220 VAL B CG2 1 +ATOM 7702 N N . HIS C 1 159 ? -45.440 0.233 -105.204 1.00 45.67 ? 221 HIS B N 1 +ATOM 7703 C CA . HIS C 1 159 ? -46.114 -0.704 -106.082 1.00 43.68 ? 221 HIS B CA 1 +ATOM 7704 C C . HIS C 1 159 ? -45.101 -1.252 -107.077 1.00 45.17 ? 221 HIS B C 1 +ATOM 7705 O O . HIS C 1 159 ? -44.131 -0.574 -107.433 1.00 46.43 ? 221 HIS B O 1 +ATOM 7706 C CB . HIS C 1 159 ? -47.297 -0.037 -106.798 1.00 50.89 ? 221 HIS B CB 1 +ATOM 7707 C CG . HIS C 1 159 ? -48.423 0.343 -105.882 1.00 54.52 ? 221 HIS B CG 1 +ATOM 7708 N ND1 . HIS C 1 159 ? -48.754 -0.386 -104.760 1.00 49.02 ? 221 HIS B ND1 1 +ATOM 7709 C CD2 . HIS C 1 159 ? -49.281 1.391 -105.912 1.00 55.85 ? 221 HIS B CD2 1 +ATOM 7710 C CE1 . HIS C 1 159 ? -49.774 0.188 -104.147 1.00 43.21 ? 221 HIS B CE1 1 +ATOM 7711 N NE2 . HIS C 1 159 ? -50.111 1.269 -104.824 1.00 44.95 ? 221 HIS B NE2 1 +ATOM 7712 N N . LEU C 1 160 ? -45.304 -2.505 -107.479 1.00 45.60 ? 222 LEU B N 1 +ATOM 7713 C CA . LEU C 1 160 ? -44.360 -3.204 -108.351 1.00 38.00 ? 222 LEU B CA 1 +ATOM 7714 C C . LEU C 1 160 ? -44.473 -2.655 -109.764 1.00 38.00 ? 222 LEU B C 1 +ATOM 7715 O O . LEU C 1 160 ? -45.374 -3.025 -110.520 1.00 38.00 ? 222 LEU B O 1 +ATOM 7716 C CB . LEU C 1 160 ? -44.623 -4.704 -108.332 1.00 38.76 ? 222 LEU B CB 1 +ATOM 7717 C CG . LEU C 1 160 ? -43.375 -5.578 -108.227 1.00 39.45 ? 222 LEU B CG 1 +ATOM 7718 C CD1 . LEU C 1 160 ? -43.757 -7.043 -108.342 1.00 47.74 ? 222 LEU B CD1 1 +ATOM 7719 C CD2 . LEU C 1 160 ? -42.335 -5.202 -109.267 1.00 38.00 ? 222 LEU B CD2 1 +ATOM 7720 N N . LYS C 1 161 ? -43.534 -1.787 -110.128 1.00 38.00 ? 223 LYS B N 1 +ATOM 7721 C CA . LYS C 1 161 ? -43.434 -1.251 -111.475 1.00 38.00 ? 223 LYS B CA 1 +ATOM 7722 C C . LYS C 1 161 ? -41.995 -0.814 -111.694 1.00 38.00 ? 223 LYS B C 1 +ATOM 7723 O O . LYS C 1 161 ? -41.377 -0.223 -110.804 1.00 39.10 ? 223 LYS B O 1 +ATOM 7724 C CB . LYS C 1 161 ? -44.392 -0.075 -111.689 1.00 38.00 ? 223 LYS B CB 1 +ATOM 7725 C CG . LYS C 1 161 ? -44.100 1.135 -110.814 1.00 39.32 ? 223 LYS B CG 1 +ATOM 7726 C CD . LYS C 1 161 ? -45.141 2.221 -111.005 1.00 42.67 ? 223 LYS B CD 1 +ATOM 7727 C CE . LYS C 1 161 ? -45.164 3.168 -109.818 1.00 41.22 ? 223 LYS B CE 1 +ATOM 7728 N NZ . LYS C 1 161 ? -46.248 4.179 -109.935 1.00 43.69 ? 223 LYS B NZ 1 +ATOM 7729 N N . LEU C 1 162 ? -41.470 -1.112 -112.877 1.00 38.76 ? 224 LEU B N 1 +ATOM 7730 C CA . LEU C 1 162 ? -40.102 -0.778 -113.241 1.00 38.00 ? 224 LEU B CA 1 +ATOM 7731 C C . LEU C 1 162 ? -40.116 0.073 -114.499 1.00 38.00 ? 224 LEU B C 1 +ATOM 7732 O O . LEU C 1 162 ? -41.124 0.167 -115.203 1.00 40.08 ? 224 LEU B O 1 +ATOM 7733 C CB . LEU C 1 162 ? -39.262 -2.041 -113.460 1.00 38.00 ? 224 LEU B CB 1 +ATOM 7734 C CG . LEU C 1 162 ? -39.328 -3.064 -112.330 1.00 38.00 ? 224 LEU B CG 1 +ATOM 7735 C CD1 . LEU C 1 162 ? -38.527 -4.305 -112.664 1.00 38.00 ? 224 LEU B CD1 1 +ATOM 7736 C CD2 . LEU C 1 162 ? -38.819 -2.428 -111.066 1.00 38.77 ? 224 LEU B CD2 1 +ATOM 7737 N N . VAL C 1 163 ? -38.981 0.698 -114.782 1.00 38.00 ? 225 VAL B N 1 +ATOM 7738 C CA . VAL C 1 163 ? -38.820 1.519 -115.974 1.00 38.00 ? 225 VAL B CA 1 +ATOM 7739 C C . VAL C 1 163 ? -37.723 0.895 -116.828 1.00 39.03 ? 225 VAL B C 1 +ATOM 7740 O O . VAL C 1 163 ? -36.568 0.792 -116.396 1.00 45.04 ? 225 VAL B O 1 +ATOM 7741 C CB . VAL C 1 163 ? -38.513 2.981 -115.613 1.00 38.00 ? 225 VAL B CB 1 +ATOM 7742 C CG1 . VAL C 1 163 ? -37.565 3.041 -114.437 1.00 38.00 ? 225 VAL B CG1 1 +ATOM 7743 C CG2 . VAL C 1 163 ? -37.944 3.722 -116.811 1.00 40.16 ? 225 VAL B CG2 1 +ATOM 7744 N N . LEU C 1 164 ? -38.084 0.475 -118.033 1.00 38.00 ? 226 LEU B N 1 +ATOM 7745 C CA . LEU C 1 164 ? -37.182 -0.229 -118.926 1.00 38.00 ? 226 LEU B CA 1 +ATOM 7746 C C . LEU C 1 164 ? -36.678 0.719 -120.010 1.00 46.29 ? 226 LEU B C 1 +ATOM 7747 O O . LEU C 1 164 ? -37.355 1.683 -120.377 1.00 48.67 ? 226 LEU B O 1 +ATOM 7748 C CB . LEU C 1 164 ? -37.907 -1.420 -119.557 1.00 38.00 ? 226 LEU B CB 1 +ATOM 7749 C CG . LEU C 1 164 ? -37.980 -2.756 -118.811 1.00 38.00 ? 226 LEU B CG 1 +ATOM 7750 C CD1 . LEU C 1 164 ? -38.131 -2.597 -117.312 1.00 38.00 ? 226 LEU B CD1 1 +ATOM 7751 C CD2 . LEU C 1 164 ? -39.143 -3.566 -119.354 1.00 38.00 ? 226 LEU B CD2 1 +ATOM 7752 N N . ARG C 1 165 ? -35.479 0.443 -120.523 1.00 47.22 ? 227 ARG B N 1 +ATOM 7753 C CA . ARG C 1 165 ? -34.903 1.206 -121.624 1.00 43.66 ? 227 ARG B CA 1 +ATOM 7754 C C . ARG C 1 165 ? -34.583 0.260 -122.765 1.00 47.96 ? 227 ARG B C 1 +ATOM 7755 O O . ARG C 1 165 ? -34.061 -0.838 -122.546 1.00 43.85 ? 227 ARG B O 1 +ATOM 7756 C CB . ARG C 1 165 ? -33.621 1.949 -121.238 1.00 40.32 ? 227 ARG B CB 1 +ATOM 7757 C CG . ARG C 1 165 ? -33.687 2.700 -119.936 1.00 61.52 ? 227 ARG B CG 1 +ATOM 7758 C CD . ARG C 1 165 ? -32.735 3.884 -119.939 1.00 69.10 ? 227 ARG B CD 1 +ATOM 7759 N NE . ARG C 1 165 ? -33.153 4.885 -120.916 1.00 53.91 ? 227 ARG B NE 1 +ATOM 7760 C CZ . ARG C 1 165 ? -32.848 6.175 -120.834 1.00 49.03 ? 227 ARG B CZ 1 +ATOM 7761 N NH1 . ARG C 1 165 ? -32.126 6.622 -119.817 1.00 51.04 ? 227 ARG B NH1 1 +ATOM 7762 N NH2 . ARG C 1 165 ? -33.280 7.020 -121.758 1.00 48.18 ? 227 ARG B NH2 1 +ATOM 7763 N N . PHE C 1 166 ? -34.897 0.690 -123.981 1.00 49.03 ? 228 PHE B N 1 +ATOM 7764 C CA . PHE C 1 166 ? -34.702 -0.121 -125.168 1.00 40.75 ? 228 PHE B CA 1 +ATOM 7765 C C . PHE C 1 166 ? -33.544 0.417 -125.994 1.00 38.00 ? 228 PHE B C 1 +ATOM 7766 O O . PHE C 1 166 ? -33.035 1.517 -125.766 1.00 38.00 ? 228 PHE B O 1 +ATOM 7767 C CB . PHE C 1 166 ? -35.988 -0.165 -125.987 1.00 39.28 ? 228 PHE B CB 1 +ATOM 7768 C CG . PHE C 1 166 ? -37.198 -0.486 -125.167 1.00 44.13 ? 228 PHE B CG 1 +ATOM 7769 C CD1 . PHE C 1 166 ? -37.472 -1.793 -124.792 1.00 41.15 ? 228 PHE B CD1 1 +ATOM 7770 C CD2 . PHE C 1 166 ? -38.051 0.518 -124.750 1.00 43.68 ? 228 PHE B CD2 1 +ATOM 7771 C CE1 . PHE C 1 166 ? -38.583 -2.089 -124.032 1.00 38.00 ? 228 PHE B CE1 1 +ATOM 7772 C CE2 . PHE C 1 166 ? -39.161 0.224 -123.989 1.00 39.07 ? 228 PHE B CE2 1 +ATOM 7773 C CZ . PHE C 1 166 ? -39.425 -1.080 -123.633 1.00 38.00 ? 228 PHE B CZ 1 +ATOM 7774 N N . SER C 1 167 ? -33.162 -0.369 -126.998 1.00 38.00 ? 229 SER B N 1 +ATOM 7775 C CA . SER C 1 167 ? -31.984 -0.045 -127.788 1.00 38.00 ? 229 SER B CA 1 +ATOM 7776 C C . SER C 1 167 ? -32.116 1.276 -128.537 1.00 38.00 ? 229 SER B C 1 +ATOM 7777 O O . SER C 1 167 ? -31.095 1.883 -128.873 1.00 41.34 ? 229 SER B O 1 +ATOM 7778 C CB . SER C 1 167 ? -31.699 -1.189 -128.756 1.00 40.08 ? 229 SER B CB 1 +ATOM 7779 O OG . SER C 1 167 ? -32.835 -1.443 -129.556 1.00 44.72 ? 229 SER B OG 1 +ATOM 7780 N N . ASP C 1 168 ? -33.333 1.756 -128.787 1.00 38.58 ? 230 ASP B N 1 +ATOM 7781 C CA . ASP C 1 168 ? -33.501 3.054 -129.426 1.00 38.00 ? 230 ASP B CA 1 +ATOM 7782 C C . ASP C 1 168 ? -33.487 4.198 -128.426 1.00 38.00 ? 230 ASP B C 1 +ATOM 7783 O O . ASP C 1 168 ? -33.838 5.321 -128.796 1.00 38.00 ? 230 ASP B O 1 +ATOM 7784 C CB . ASP C 1 168 ? -34.802 3.098 -130.244 1.00 40.90 ? 230 ASP B CB 1 +ATOM 7785 C CG . ASP C 1 168 ? -36.060 2.948 -129.389 1.00 44.85 ? 230 ASP B CG 1 +ATOM 7786 O OD1 . ASP C 1 168 ? -35.951 2.685 -128.173 1.00 50.37 ? 230 ASP B OD1 1 +ATOM 7787 O OD2 . ASP C 1 168 ? -37.172 3.117 -129.937 1.00 43.80 ? 230 ASP B OD2 1 +ATOM 7788 N N . PHE C 1 169 ? -33.074 3.935 -127.184 1.00 41.76 ? 231 PHE B N 1 +ATOM 7789 C CA . PHE C 1 169 ? -32.932 4.854 -126.058 1.00 44.48 ? 231 PHE B CA 1 +ATOM 7790 C C . PHE C 1 169 ? -34.272 5.141 -125.369 1.00 45.99 ? 231 PHE B C 1 +ATOM 7791 O O . PHE C 1 169 ? -34.273 5.740 -124.292 1.00 46.89 ? 231 PHE B O 1 +ATOM 7792 C CB . PHE C 1 169 ? -32.269 6.193 -126.446 1.00 47.11 ? 231 PHE B CB 1 +ATOM 7793 C CG . PHE C 1 169 ? -31.722 6.971 -125.282 1.00 45.97 ? 231 PHE B CG 1 +ATOM 7794 C CD1 . PHE C 1 169 ? -30.596 6.540 -124.605 1.00 51.76 ? 231 PHE B CD1 1 +ATOM 7795 C CD2 . PHE C 1 169 ? -32.338 8.140 -124.871 1.00 49.50 ? 231 PHE B CD2 1 +ATOM 7796 C CE1 . PHE C 1 169 ? -30.097 7.262 -123.535 1.00 57.42 ? 231 PHE B CE1 1 +ATOM 7797 C CE2 . PHE C 1 169 ? -31.846 8.864 -123.809 1.00 55.26 ? 231 PHE B CE2 1 +ATOM 7798 C CZ . PHE C 1 169 ? -30.723 8.426 -123.138 1.00 56.63 ? 231 PHE B CZ 1 +ATOM 7799 N N . GLY C 1 170 ? -35.405 4.735 -125.940 1.00 47.89 ? 232 GLY B N 1 +ATOM 7800 C CA . GLY C 1 170 ? -36.687 5.040 -125.338 1.00 49.36 ? 232 GLY B CA 1 +ATOM 7801 C C . GLY C 1 170 ? -36.938 4.280 -124.049 1.00 48.86 ? 232 GLY B C 1 +ATOM 7802 O O . GLY C 1 170 ? -36.274 3.296 -123.724 1.00 52.81 ? 232 GLY B O 1 +ATOM 7803 N N . LYS C 1 171 ? -37.933 4.753 -123.301 1.00 43.26 ? 233 LYS B N 1 +ATOM 7804 C CA . LYS C 1 171 ? -38.303 4.161 -122.025 1.00 43.75 ? 233 LYS B CA 1 +ATOM 7805 C C . LYS C 1 171 ? -39.783 3.806 -122.038 1.00 42.12 ? 233 LYS B C 1 +ATOM 7806 O O . LYS C 1 171 ? -40.547 4.254 -122.897 1.00 47.29 ? 233 LYS B O 1 +ATOM 7807 C CB . LYS C 1 171 ? -37.986 5.102 -120.851 1.00 48.01 ? 233 LYS B CB 1 +ATOM 7808 C CG . LYS C 1 171 ? -36.503 5.400 -120.665 1.00 45.21 ? 233 LYS B CG 1 +ATOM 7809 C CD . LYS C 1 171 ? -36.242 6.216 -119.405 1.00 38.79 ? 233 LYS B CD 1 +ATOM 7810 C CE . LYS C 1 171 ? -36.332 7.706 -119.696 1.00 47.55 ? 233 LYS B CE 1 +ATOM 7811 N NZ . LYS C 1 171 ? -35.911 8.575 -118.561 1.00 51.49 ? 233 LYS B NZ 1 +ATOM 7812 N N . ALA C 1 172 ? -40.176 2.988 -121.065 1.00 38.00 ? 234 ALA B N 1 +ATOM 7813 C CA . ALA C 1 172 ? -41.544 2.513 -120.945 1.00 38.00 ? 234 ALA B CA 1 +ATOM 7814 C C . ALA C 1 172 ? -41.742 1.976 -119.540 1.00 38.00 ? 234 ALA B C 1 +ATOM 7815 O O . ALA C 1 172 ? -40.848 1.332 -118.988 1.00 38.60 ? 234 ALA B O 1 +ATOM 7816 C CB . ALA C 1 172 ? -41.863 1.425 -121.971 1.00 38.00 ? 234 ALA B CB 1 +ATOM 7817 N N . MET C 1 173 ? -42.915 2.241 -118.977 1.00 39.78 ? 235 MET B N 1 +ATOM 7818 C CA . MET C 1 173 ? -43.251 1.822 -117.623 1.00 38.00 ? 235 MET B CA 1 +ATOM 7819 C C . MET C 1 173 ? -43.789 0.397 -117.655 1.00 38.00 ? 235 MET B C 1 +ATOM 7820 O O . MET C 1 173 ? -44.831 0.134 -118.262 1.00 38.00 ? 235 MET B O 1 +ATOM 7821 C CB . MET C 1 173 ? -44.276 2.777 -117.017 1.00 38.00 ? 235 MET B CB 1 +ATOM 7822 C CG . MET C 1 173 ? -44.573 2.533 -115.555 1.00 43.41 ? 235 MET B CG 1 +ATOM 7823 S SD . MET C 1 173 ? -43.149 2.825 -114.500 1.00 40.90 ? 235 MET B SD 1 +ATOM 7824 C CE . MET C 1 173 ? -42.837 4.555 -114.841 1.00 47.94 ? 235 MET B CE 1 +ATOM 7825 N N . PHE C 1 174 ? -43.081 -0.515 -117.003 1.00 38.00 ? 236 PHE B N 1 +ATOM 7826 C CA . PHE C 1 174 ? -43.411 -1.932 -117.032 1.00 38.00 ? 236 PHE B CA 1 +ATOM 7827 C C . PHE C 1 174 ? -44.246 -2.288 -115.809 1.00 38.00 ? 236 PHE B C 1 +ATOM 7828 O O . PHE C 1 174 ? -43.852 -1.998 -114.676 1.00 38.00 ? 236 PHE B O 1 +ATOM 7829 C CB . PHE C 1 174 ? -42.147 -2.785 -117.092 1.00 38.00 ? 236 PHE B CB 1 +ATOM 7830 C CG . PHE C 1 174 ? -42.415 -4.254 -117.035 1.00 38.00 ? 236 PHE B CG 1 +ATOM 7831 C CD1 . PHE C 1 174 ? -42.820 -4.939 -118.163 1.00 38.00 ? 236 PHE B CD1 1 +ATOM 7832 C CD2 . PHE C 1 174 ? -42.264 -4.950 -115.852 1.00 38.00 ? 236 PHE B CD2 1 +ATOM 7833 C CE1 . PHE C 1 174 ? -43.073 -6.291 -118.110 1.00 38.00 ? 236 PHE B CE1 1 +ATOM 7834 C CE2 . PHE C 1 174 ? -42.512 -6.301 -115.792 1.00 38.00 ? 236 PHE B CE2 1 +ATOM 7835 C CZ . PHE C 1 174 ? -42.917 -6.975 -116.923 1.00 38.00 ? 236 PHE B CZ 1 +ATOM 7836 N N . LYS C 1 175 ? -45.411 -2.882 -116.049 1.00 38.00 ? 237 LYS B N 1 +ATOM 7837 C CA . LYS C 1 175 ? -46.285 -3.401 -115.006 1.00 38.00 ? 237 LYS B CA 1 +ATOM 7838 C C . LYS C 1 175 ? -46.411 -4.909 -115.181 1.00 38.00 ? 237 LYS B C 1 +ATOM 7839 O O . LYS C 1 175 ? -46.921 -5.359 -116.221 1.00 38.00 ? 237 LYS B O 1 +ATOM 7840 C CB . LYS C 1 175 ? -47.660 -2.734 -115.082 1.00 39.18 ? 237 LYS B CB 1 +ATOM 7841 C CG . LYS C 1 175 ? -47.665 -1.223 -114.866 1.00 38.00 ? 237 LYS B CG 1 +ATOM 7842 C CD . LYS C 1 175 ? -48.088 -0.849 -113.448 1.00 38.00 ? 237 LYS B CD 1 +ATOM 7843 C CE . LYS C 1 175 ? -48.228 0.664 -113.291 1.00 40.07 ? 237 LYS B CE 1 +ATOM 7844 N NZ . LYS C 1 175 ? -49.248 1.242 -114.211 1.00 38.00 ? 237 LYS B NZ 1 +ATOM 7845 N N . PRO C 1 176 ? -45.974 -5.727 -114.229 1.00 38.00 ? 238 PRO B N 1 +ATOM 7846 C CA . PRO C 1 176 ? -46.022 -7.181 -114.413 1.00 38.00 ? 238 PRO B CA 1 +ATOM 7847 C C . PRO C 1 176 ? -47.425 -7.736 -114.197 1.00 38.00 ? 238 PRO B C 1 +ATOM 7848 O O . PRO C 1 176 ? -48.317 -7.071 -113.673 1.00 39.89 ? 238 PRO B O 1 +ATOM 7849 C CB . PRO C 1 176 ? -45.062 -7.697 -113.340 1.00 38.00 ? 238 PRO B CB 1 +ATOM 7850 C CG . PRO C 1 176 ? -45.166 -6.693 -112.257 1.00 38.00 ? 238 PRO B CG 1 +ATOM 7851 C CD . PRO C 1 176 ? -45.364 -5.360 -112.940 1.00 38.00 ? 238 PRO B CD 1 +ATOM 7852 N N . MET C 1 177 ? -47.597 -8.993 -114.603 1.00 38.00 ? 239 MET B N 1 +ATOM 7853 C CA . MET C 1 177 ? -48.867 -9.677 -114.405 1.00 38.00 ? 239 MET B CA 1 +ATOM 7854 C C . MET C 1 177 ? -49.080 -9.987 -112.931 1.00 43.70 ? 239 MET B C 1 +ATOM 7855 O O . MET C 1 177 ? -48.220 -10.587 -112.279 1.00 45.25 ? 239 MET B O 1 +ATOM 7856 C CB . MET C 1 177 ? -48.920 -10.968 -115.219 1.00 39.58 ? 239 MET B CB 1 +ATOM 7857 C CG . MET C 1 177 ? -50.220 -11.736 -115.023 1.00 45.51 ? 239 MET B CG 1 +ATOM 7858 S SD . MET C 1 177 ? -50.443 -13.179 -116.081 1.00 44.00 ? 239 MET B SD 1 +ATOM 7859 C CE . MET C 1 177 ? -49.317 -14.349 -115.318 1.00 40.47 ? 239 MET B CE 1 +ATOM 7860 N N . ARG C 1 178 ? -50.251 -9.617 -112.418 1.00 44.92 ? 240 ARG B N 1 +ATOM 7861 C CA . ARG C 1 178 ? -50.562 -9.777 -111.007 1.00 42.02 ? 240 ARG B CA 1 +ATOM 7862 C C . ARG C 1 178 ? -51.809 -10.609 -110.757 1.00 38.00 ? 240 ARG B C 1 +ATOM 7863 O O . ARG C 1 178 ? -52.126 -10.877 -109.594 1.00 42.42 ? 240 ARG B O 1 +ATOM 7864 C CB . ARG C 1 178 ? -50.728 -8.400 -110.347 1.00 47.43 ? 240 ARG B CB 1 +ATOM 7865 C CG . ARG C 1 178 ? -49.564 -7.446 -110.588 1.00 48.37 ? 240 ARG B CG 1 +ATOM 7866 C CD . ARG C 1 178 ? -48.737 -7.270 -109.337 1.00 47.74 ? 240 ARG B CD 1 +ATOM 7867 N NE . ARG C 1 178 ? -48.774 -8.468 -108.507 1.00 51.39 ? 240 ARG B NE 1 +ATOM 7868 C CZ . ARG C 1 178 ? -48.082 -8.615 -107.383 1.00 64.07 ? 240 ARG B CZ 1 +ATOM 7869 N NH1 . ARG C 1 178 ? -47.292 -7.635 -106.966 1.00 60.02 ? 240 ARG B NH1 1 +ATOM 7870 N NH2 . ARG C 1 178 ? -48.177 -9.738 -106.679 1.00 68.40 ? 240 ARG B NH2 1 +ATOM 7871 N N . GLN C 1 179 ? -52.521 -11.025 -111.801 1.00 38.00 ? 241 GLN B N 1 +ATOM 7872 C CA . GLN C 1 179 ? -53.751 -11.785 -111.630 1.00 41.15 ? 241 GLN B CA 1 +ATOM 7873 C C . GLN C 1 179 ? -54.073 -12.523 -112.919 1.00 41.22 ? 241 GLN B C 1 +ATOM 7874 O O . GLN C 1 179 ? -53.701 -12.082 -114.010 1.00 45.67 ? 241 GLN B O 1 +ATOM 7875 C CB . GLN C 1 179 ? -54.928 -10.884 -111.243 1.00 45.29 ? 241 GLN B CB 1 +ATOM 7876 C CG . GLN C 1 179 ? -55.276 -10.876 -109.768 1.00 39.18 ? 241 GLN B CG 1 +ATOM 7877 C CD . GLN C 1 179 ? -56.575 -10.154 -109.501 1.00 40.77 ? 241 GLN B CD 1 +ATOM 7878 O OE1 . GLN C 1 179 ? -56.938 -9.228 -110.220 1.00 39.49 ? 241 GLN B OE1 1 +ATOM 7879 N NE2 . GLN C 1 179 ? -57.297 -10.592 -108.482 1.00 51.67 ? 241 GLN B NE2 1 +ATOM 7880 N N . GLN C 1 180 ? -54.792 -13.635 -112.785 1.00 40.45 ? 242 GLN B N 1 +ATOM 7881 C CA . GLN C 1 180 ? -55.223 -14.377 -113.959 1.00 49.33 ? 242 GLN B CA 1 +ATOM 7882 C C . GLN C 1 180 ? -56.242 -13.561 -114.754 1.00 46.51 ? 242 GLN B C 1 +ATOM 7883 O O . GLN C 1 180 ? -56.651 -12.469 -114.356 1.00 51.53 ? 242 GLN B O 1 +ATOM 7884 C CB . GLN C 1 180 ? -55.814 -15.729 -113.555 1.00 50.49 ? 242 GLN B CB 1 +ATOM 7885 C CG . GLN C 1 180 ? -54.820 -16.657 -112.889 1.00 46.95 ? 242 GLN B CG 1 +ATOM 7886 C CD . GLN C 1 180 ? -53.704 -17.084 -113.829 1.00 55.88 ? 242 GLN B CD 1 +ATOM 7887 O OE1 . GLN C 1 180 ? -53.895 -17.176 -115.043 1.00 62.72 ? 242 GLN B OE1 1 +ATOM 7888 N NE2 . GLN C 1 180 ? -52.525 -17.326 -113.271 1.00 63.12 ? 242 GLN B NE2 1 +ATOM 7889 N N . ARG C 1 181 ? -56.634 -14.095 -115.913 1.00 41.03 ? 243 ARG B N 1 +ATOM 7890 C CA . ARG C 1 181 ? -57.625 -13.410 -116.739 1.00 42.48 ? 243 ARG B CA 1 +ATOM 7891 C C . ARG C 1 181 ? -59.022 -13.557 -116.151 1.00 49.01 ? 243 ARG B C 1 +ATOM 7892 O O . ARG C 1 181 ? -59.784 -12.585 -116.078 1.00 49.16 ? 243 ARG B O 1 +ATOM 7893 C CB . ARG C 1 181 ? -57.589 -13.942 -118.172 1.00 42.87 ? 243 ARG B CB 1 +ATOM 7894 C CG . ARG C 1 181 ? -56.317 -13.621 -118.910 1.00 38.00 ? 243 ARG B CG 1 +ATOM 7895 C CD . ARG C 1 181 ? -56.020 -12.138 -118.850 1.00 38.00 ? 243 ARG B CD 1 +ATOM 7896 N NE . ARG C 1 181 ? -54.605 -11.887 -119.084 1.00 38.00 ? 243 ARG B NE 1 +ATOM 7897 C CZ . ARG C 1 181 ? -54.046 -11.815 -120.285 1.00 38.00 ? 243 ARG B CZ 1 +ATOM 7898 N NH1 . ARG C 1 181 ? -54.783 -11.969 -121.373 1.00 38.00 ? 243 ARG B NH1 1 +ATOM 7899 N NH2 . ARG C 1 181 ? -52.745 -11.592 -120.395 1.00 38.81 ? 243 ARG B NH2 1 +ATOM 7900 N N . ASP C 1 182 ? -59.381 -14.772 -115.743 1.00 51.29 ? 244 ASP B N 1 +ATOM 7901 C CA . ASP C 1 182 ? -60.712 -15.052 -115.222 1.00 53.43 ? 244 ASP B CA 1 +ATOM 7902 C C . ASP C 1 182 ? -60.836 -14.742 -113.733 1.00 51.58 ? 244 ASP B C 1 +ATOM 7903 O O . ASP C 1 182 ? -61.683 -15.318 -113.051 1.00 55.50 ? 244 ASP B O 1 +ATOM 7904 C CB . ASP C 1 182 ? -61.065 -16.517 -115.477 1.00 59.19 ? 244 ASP B CB 1 +ATOM 7905 C CG . ASP C 1 182 ? -59.989 -17.468 -114.978 1.00 57.82 ? 244 ASP B CG 1 +ATOM 7906 O OD1 . ASP C 1 182 ? -59.885 -17.667 -113.748 1.00 56.94 ? 244 ASP B OD1 1 +ATOM 7907 O OD2 . ASP C 1 182 ? -59.245 -18.019 -115.821 1.00 54.16 ? 244 ASP B OD2 1 +ATOM 7908 N N . GLU C 1 183 ? -60.017 -13.819 -113.233 1.00 52.70 ? 245 GLU B N 1 +ATOM 7909 C CA . GLU C 1 183 ? -60.009 -13.463 -111.821 1.00 53.96 ? 245 GLU B CA 1 +ATOM 7910 C C . GLU C 1 183 ? -60.522 -12.043 -111.630 1.00 53.80 ? 245 GLU B C 1 +ATOM 7911 O O . GLU C 1 183 ? -60.137 -11.127 -112.366 1.00 48.21 ? 245 GLU B O 1 +ATOM 7912 C CB . GLU C 1 183 ? -58.600 -13.582 -111.219 1.00 54.20 ? 245 GLU B CB 1 +ATOM 7913 C CG . GLU C 1 183 ? -58.179 -15.001 -110.833 1.00 63.81 ? 245 GLU B CG 1 +ATOM 7914 C CD . GLU C 1 183 ? -56.892 -15.030 -110.010 1.00 66.12 ? 245 GLU B CD 1 +ATOM 7915 O OE1 . GLU C 1 183 ? -56.328 -13.947 -109.744 1.00 59.89 ? 245 GLU B OE1 1 +ATOM 7916 O OE2 . GLU C 1 183 ? -56.455 -16.133 -109.613 1.00 67.31 ? 245 GLU B OE2 1 +ATOM 7917 N N . GLU C 1 184 ? -61.382 -11.864 -110.628 1.00 58.61 ? 246 GLU B N 1 +ATOM 7918 C CA . GLU C 1 184 ? -61.938 -10.563 -110.283 1.00 56.29 ? 246 GLU B CA 1 +ATOM 7919 C C . GLU C 1 184 ? -61.317 -10.061 -108.989 1.00 49.00 ? 246 GLU B C 1 +ATOM 7920 O O . GLU C 1 184 ? -60.745 -10.832 -108.214 1.00 51.15 ? 246 GLU B O 1 +ATOM 7921 C CB . GLU C 1 184 ? -63.468 -10.616 -110.119 1.00 56.13 ? 246 GLU B CB 1 +ATOM 7922 C CG . GLU C 1 184 ? -64.225 -11.318 -111.243 1.00 58.04 ? 246 GLU B CG 1 +ATOM 7923 C CD . GLU C 1 184 ? -65.738 -11.119 -111.168 1.00 59.57 ? 246 GLU B CD 1 +ATOM 7924 O OE1 . GLU C 1 184 ? -66.187 -9.987 -110.882 1.00 59.29 ? 246 GLU B OE1 1 +ATOM 7925 O OE2 . GLU C 1 184 ? -66.479 -12.099 -111.398 1.00 59.36 ? 246 GLU B OE2 1 +ATOM 7926 N N . THR C 1 185 ? -61.422 -8.744 -108.774 1.00 49.55 ? 247 THR B N 1 +ATOM 7927 C CA . THR C 1 185 ? -61.138 -8.195 -107.456 1.00 53.06 ? 247 THR B CA 1 +ATOM 7928 C C . THR C 1 185 ? -62.168 -8.814 -106.528 1.00 58.45 ? 247 THR B C 1 +ATOM 7929 O O . THR C 1 185 ? -63.375 -8.591 -106.700 1.00 54.75 ? 247 THR B O 1 +ATOM 7930 C CB . THR C 1 185 ? -61.226 -6.667 -107.407 1.00 48.05 ? 247 THR B CB 1 +ATOM 7931 O OG1 . THR C 1 185 ? -62.425 -6.281 -106.725 1.00 56.91 ? 247 THR B OG1 1 +ATOM 7932 C CG2 . THR C 1 185 ? -61.247 -6.080 -108.792 1.00 43.40 ? 247 THR B CG2 1 +ATOM 7933 N N . PRO C 1 186 ? -61.743 -9.630 -105.571 1.00 59.87 ? 248 PRO B N 1 +ATOM 7934 C CA . PRO C 1 186 ? -62.718 -10.321 -104.726 1.00 65.10 ? 248 PRO B CA 1 +ATOM 7935 C C . PRO C 1 186 ? -63.527 -9.315 -103.924 1.00 60.88 ? 248 PRO B C 1 +ATOM 7936 O O . PRO C 1 186 ? -63.047 -8.234 -103.579 1.00 54.53 ? 248 PRO B O 1 +ATOM 7937 C CB . PRO C 1 186 ? -61.848 -11.209 -103.828 1.00 56.50 ? 248 PRO B CB 1 +ATOM 7938 C CG . PRO C 1 186 ? -60.526 -10.521 -103.805 1.00 54.81 ? 248 PRO B CG 1 +ATOM 7939 C CD . PRO C 1 186 ? -60.355 -9.865 -105.136 1.00 49.41 ? 248 PRO B CD 1 +ATOM 7940 N N . VAL C 1 187 ? -64.793 -9.659 -103.678 1.00 61.78 ? 249 VAL B N 1 +ATOM 7941 C CA . VAL C 1 187 ? -65.597 -8.847 -102.781 1.00 58.27 ? 249 VAL B CA 1 +ATOM 7942 C C . VAL C 1 187 ? -64.895 -8.791 -101.429 1.00 54.11 ? 249 VAL B C 1 +ATOM 7943 O O . VAL C 1 187 ? -64.144 -9.701 -101.056 1.00 54.32 ? 249 VAL B O 1 +ATOM 7944 C CB . VAL C 1 187 ? -67.025 -9.404 -102.650 1.00 68.03 ? 249 VAL B CB 1 +ATOM 7945 C CG1 . VAL C 1 187 ? -67.724 -9.387 -104.006 1.00 68.41 ? 249 VAL B CG1 1 +ATOM 7946 C CG2 . VAL C 1 187 ? -66.996 -10.817 -102.069 1.00 57.42 ? 249 VAL B CG2 1 +ATOM 7947 N N . ASP C 1 188 ? -65.141 -7.707 -100.694 1.00 55.39 ? 250 ASP B N 1 +ATOM 7948 C CA . ASP C 1 188 ? -64.452 -7.295 -99.463 1.00 57.08 ? 250 ASP B CA 1 +ATOM 7949 C C . ASP C 1 188 ? -63.152 -6.565 -99.775 1.00 56.20 ? 250 ASP B C 1 +ATOM 7950 O O . ASP C 1 188 ? -62.361 -6.308 -98.856 1.00 54.40 ? 250 ASP B O 1 +ATOM 7951 C CB . ASP C 1 188 ? -64.131 -8.440 -98.490 1.00 44.53 ? 250 ASP B CB 1 +ATOM 7952 C CG . ASP C 1 188 ? -65.331 -9.324 -98.195 1.00 48.27 ? 250 ASP B CG 1 +ATOM 7953 O OD1 . ASP C 1 188 ? -66.464 -8.805 -98.126 1.00 54.88 ? 250 ASP B OD1 1 +ATOM 7954 O OD2 . ASP C 1 188 ? -65.132 -10.542 -98.006 1.00 45.50 ? 250 ASP B OD2 1 +ATOM 7955 N N . PHE C 1 189 ? -62.911 -6.197 -101.028 1.00 55.48 ? 251 PHE B N 1 +ATOM 7956 C CA . PHE C 1 189 ? -61.694 -5.500 -101.418 1.00 49.46 ? 251 PHE B CA 1 +ATOM 7957 C C . PHE C 1 189 ? -62.040 -4.051 -101.714 1.00 49.76 ? 251 PHE B C 1 +ATOM 7958 O O . PHE C 1 189 ? -62.843 -3.773 -102.612 1.00 53.47 ? 251 PHE B O 1 +ATOM 7959 C CB . PHE C 1 189 ? -61.042 -6.161 -102.635 1.00 51.50 ? 251 PHE B CB 1 +ATOM 7960 C CG . PHE C 1 189 ? -59.821 -6.973 -102.306 1.00 46.62 ? 251 PHE B CG 1 +ATOM 7961 C CD1 . PHE C 1 189 ? -59.922 -8.142 -101.574 1.00 47.34 ? 251 PHE B CD1 1 +ATOM 7962 C CD2 . PHE C 1 189 ? -58.572 -6.559 -102.722 1.00 48.40 ? 251 PHE B CD2 1 +ATOM 7963 C CE1 . PHE C 1 189 ? -58.798 -8.886 -101.271 1.00 40.00 ? 251 PHE B CE1 1 +ATOM 7964 C CE2 . PHE C 1 189 ? -57.445 -7.296 -102.421 1.00 44.69 ? 251 PHE B CE2 1 +ATOM 7965 C CZ . PHE C 1 189 ? -57.558 -8.462 -101.695 1.00 38.53 ? 251 PHE B CZ 1 +ATOM 7966 N N . PHE C 1 190 ? -61.476 -3.137 -100.932 1.00 48.91 ? 252 PHE B N 1 +ATOM 7967 C CA . PHE C 1 190 ? -61.616 -1.724 -101.240 1.00 53.47 ? 252 PHE B CA 1 +ATOM 7968 C C . PHE C 1 190 ? -60.799 -1.368 -102.484 1.00 44.30 ? 252 PHE B C 1 +ATOM 7969 O O . PHE C 1 190 ? -59.952 -2.134 -102.952 1.00 40.73 ? 252 PHE B O 1 +ATOM 7970 C CB . PHE C 1 190 ? -61.180 -0.871 -100.050 1.00 51.52 ? 252 PHE B CB 1 +ATOM 7971 C CG . PHE C 1 190 ? -62.186 -0.813 -98.940 1.00 50.23 ? 252 PHE B CG 1 +ATOM 7972 C CD1 . PHE C 1 190 ? -63.257 0.062 -99.009 1.00 55.64 ? 252 PHE B CD1 1 +ATOM 7973 C CD2 . PHE C 1 190 ? -62.058 -1.624 -97.827 1.00 49.06 ? 252 PHE B CD2 1 +ATOM 7974 C CE1 . PHE C 1 190 ? -64.189 0.124 -97.988 1.00 58.40 ? 252 PHE B CE1 1 +ATOM 7975 C CE2 . PHE C 1 190 ? -62.984 -1.569 -96.801 1.00 53.81 ? 252 PHE B CE2 1 +ATOM 7976 C CZ . PHE C 1 190 ? -64.051 -0.692 -96.880 1.00 61.10 ? 252 PHE B CZ 1 +ATOM 7977 N N . TYR C 1 191 ? -61.044 -0.166 -103.010 1.00 43.15 ? 253 TYR B N 1 +ATOM 7978 C CA . TYR C 1 191 ? -60.341 0.259 -104.215 1.00 40.13 ? 253 TYR B CA 1 +ATOM 7979 C C . TYR C 1 191 ? -58.848 0.431 -103.955 1.00 41.43 ? 253 TYR B C 1 +ATOM 7980 O O . TYR C 1 191 ? -58.022 0.052 -104.793 1.00 43.26 ? 253 TYR B O 1 +ATOM 7981 C CB . TYR C 1 191 ? -60.957 1.552 -104.762 1.00 38.89 ? 253 TYR B CB 1 +ATOM 7982 C CG . TYR C 1 191 ? -61.354 2.545 -103.695 1.00 40.72 ? 253 TYR B CG 1 +ATOM 7983 C CD1 . TYR C 1 191 ? -62.607 2.486 -103.097 1.00 43.67 ? 253 TYR B CD1 1 +ATOM 7984 C CD2 . TYR C 1 191 ? -60.482 3.543 -103.288 1.00 45.39 ? 253 TYR B CD2 1 +ATOM 7985 C CE1 . TYR C 1 191 ? -62.977 3.386 -102.112 1.00 48.14 ? 253 TYR B CE1 1 +ATOM 7986 C CE2 . TYR C 1 191 ? -60.843 4.453 -102.303 1.00 50.50 ? 253 TYR B CE2 1 +ATOM 7987 C CZ . TYR C 1 191 ? -62.093 4.369 -101.717 1.00 51.83 ? 253 TYR B CZ 1 +ATOM 7988 O OH . TYR C 1 191 ? -62.461 5.273 -100.740 1.00 48.36 ? 253 TYR B OH 1 +ATOM 7989 N N . PHE C 1 192 ? -58.477 0.959 -102.786 1.00 45.00 ? 254 PHE B N 1 +ATOM 7990 C CA . PHE C 1 192 ? -57.075 1.270 -102.528 1.00 46.34 ? 254 PHE B CA 1 +ATOM 7991 C C . PHE C 1 192 ? -56.213 0.031 -102.314 1.00 40.40 ? 254 PHE B C 1 +ATOM 7992 O O . PHE C 1 192 ? -54.983 0.152 -102.295 1.00 38.00 ? 254 PHE B O 1 +ATOM 7993 C CB . PHE C 1 192 ? -56.954 2.218 -101.328 1.00 48.44 ? 254 PHE B CB 1 +ATOM 7994 C CG . PHE C 1 192 ? -57.854 1.868 -100.172 1.00 50.88 ? 254 PHE B CG 1 +ATOM 7995 C CD1 . PHE C 1 192 ? -57.507 0.865 -99.282 1.00 53.70 ? 254 PHE B CD1 1 +ATOM 7996 C CD2 . PHE C 1 192 ? -59.044 2.554 -99.968 1.00 49.88 ? 254 PHE B CD2 1 +ATOM 7997 C CE1 . PHE C 1 192 ? -58.329 0.548 -98.215 1.00 51.06 ? 254 PHE B CE1 1 +ATOM 7998 C CE2 . PHE C 1 192 ? -59.871 2.238 -98.904 1.00 46.75 ? 254 PHE B CE2 1 +ATOM 7999 C CZ . PHE C 1 192 ? -59.510 1.237 -98.025 1.00 50.61 ? 254 PHE B CZ 1 +ATOM 8000 N N . ILE C 1 193 ? -56.811 -1.149 -102.178 1.00 40.66 ? 255 ILE B N 1 +ATOM 8001 C CA . ILE C 1 193 ? -56.060 -2.394 -102.078 1.00 46.01 ? 255 ILE B CA 1 +ATOM 8002 C C . ILE C 1 193 ? -56.277 -3.284 -103.298 1.00 42.99 ? 255 ILE B C 1 +ATOM 8003 O O . ILE C 1 193 ? -55.820 -4.434 -103.312 1.00 38.00 ? 255 ILE B O 1 +ATOM 8004 C CB . ILE C 1 193 ? -56.390 -3.147 -100.777 1.00 45.50 ? 255 ILE B CB 1 +ATOM 8005 C CG1 . ILE C 1 193 ? -57.878 -3.513 -100.734 1.00 48.29 ? 255 ILE B CG1 1 +ATOM 8006 C CG2 . ILE C 1 193 ? -55.962 -2.325 -99.564 1.00 41.67 ? 255 ILE B CG2 1 +ATOM 8007 C CD1 . ILE C 1 193 ? -58.289 -4.362 -99.544 1.00 44.87 ? 255 ILE B CD1 1 +ATOM 8008 N N . ASP C 1 194 ? -56.956 -2.779 -104.329 1.00 40.79 ? 256 ASP B N 1 +ATOM 8009 C CA . ASP C 1 194 ? -57.146 -3.547 -105.551 1.00 40.22 ? 256 ASP B CA 1 +ATOM 8010 C C . ASP C 1 194 ? -55.799 -3.805 -106.219 1.00 39.91 ? 256 ASP B C 1 +ATOM 8011 O O . ASP C 1 194 ? -54.793 -3.149 -105.934 1.00 39.55 ? 256 ASP B O 1 +ATOM 8012 C CB . ASP C 1 194 ? -58.092 -2.819 -106.512 1.00 44.87 ? 256 ASP B CB 1 +ATOM 8013 C CG . ASP C 1 194 ? -58.811 -3.771 -107.479 1.00 46.86 ? 256 ASP B CG 1 +ATOM 8014 O OD1 . ASP C 1 194 ? -58.492 -4.982 -107.490 1.00 46.74 ? 256 ASP B OD1 1 +ATOM 8015 O OD2 . ASP C 1 194 ? -59.706 -3.308 -108.220 1.00 38.28 ? 256 ASP B OD2 1 +ATOM 8016 N N . PHE C 1 195 ? -55.793 -4.777 -107.121 1.00 39.66 ? 257 PHE B N 1 +ATOM 8017 C CA . PHE C 1 195 ? -54.558 -5.247 -107.731 1.00 39.64 ? 257 PHE B CA 1 +ATOM 8018 C C . PHE C 1 195 ? -54.052 -4.233 -108.756 1.00 42.84 ? 257 PHE B C 1 +ATOM 8019 O O . PHE C 1 195 ? -54.496 -3.085 -108.826 1.00 48.27 ? 257 PHE B O 1 +ATOM 8020 C CB . PHE C 1 195 ? -54.785 -6.619 -108.348 1.00 40.32 ? 257 PHE B CB 1 +ATOM 8021 C CG . PHE C 1 195 ? -54.750 -7.731 -107.356 1.00 39.27 ? 257 PHE B CG 1 +ATOM 8022 C CD1 . PHE C 1 195 ? -53.551 -8.333 -107.022 1.00 40.75 ? 257 PHE B CD1 1 +ATOM 8023 C CD2 . PHE C 1 195 ? -55.910 -8.171 -106.747 1.00 39.61 ? 257 PHE B CD2 1 +ATOM 8024 C CE1 . PHE C 1 195 ? -53.507 -9.359 -106.104 1.00 43.97 ? 257 PHE B CE1 1 +ATOM 8025 C CE2 . PHE C 1 195 ? -55.876 -9.203 -105.823 1.00 46.90 ? 257 PHE B CE2 1 +ATOM 8026 C CZ . PHE C 1 195 ? -54.671 -9.797 -105.502 1.00 46.30 ? 257 PHE B CZ 1 +ATOM 8027 N N . GLN C 1 196 ? -53.106 -4.666 -109.574 1.00 40.42 ? 258 GLN B N 1 +ATOM 8028 C CA . GLN C 1 196 ? -52.457 -3.813 -110.563 1.00 39.55 ? 258 GLN B CA 1 +ATOM 8029 C C . GLN C 1 196 ? -52.313 -4.664 -111.826 1.00 45.38 ? 258 GLN B C 1 +ATOM 8030 O O . GLN C 1 196 ? -51.234 -5.171 -112.140 1.00 48.33 ? 258 GLN B O 1 +ATOM 8031 C CB . GLN C 1 196 ? -51.110 -3.320 -110.052 1.00 49.85 ? 258 GLN B CB 1 +ATOM 8032 C CG . GLN C 1 196 ? -50.794 -1.886 -110.395 1.00 55.72 ? 258 GLN B CG 1 +ATOM 8033 C CD . GLN C 1 196 ? -50.774 -1.000 -109.171 1.00 49.68 ? 258 GLN B CD 1 +ATOM 8034 O OE1 . GLN C 1 196 ? -51.284 -1.375 -108.113 1.00 41.65 ? 258 GLN B OE1 1 +ATOM 8035 N NE2 . GLN C 1 196 ? -50.171 0.179 -109.302 1.00 48.56 ? 258 GLN B NE2 1 +ATOM 8036 N N . ARG C 1 197 ? -53.416 -4.837 -112.550 1.00 43.49 ? 259 ARG B N 1 +ATOM 8037 C CA . ARG C 1 197 ? -53.431 -5.763 -113.675 1.00 42.25 ? 259 ARG B CA 1 +ATOM 8038 C C . ARG C 1 197 ? -52.771 -5.143 -114.901 1.00 43.02 ? 259 ARG B C 1 +ATOM 8039 O O . ARG C 1 197 ? -53.060 -4.000 -115.272 1.00 41.21 ? 259 ARG B O 1 +ATOM 8040 C CB . ARG C 1 197 ? -54.857 -6.213 -113.994 1.00 38.00 ? 259 ARG B CB 1 +ATOM 8041 C CG . ARG C 1 197 ? -55.947 -5.362 -113.381 1.00 38.00 ? 259 ARG B CG 1 +ATOM 8042 C CD . ARG C 1 197 ? -57.221 -6.163 -113.175 1.00 38.00 ? 259 ARG B CD 1 +ATOM 8043 N NE . ARG C 1 197 ? -57.434 -6.410 -111.758 1.00 38.00 ? 259 ARG B NE 1 +ATOM 8044 C CZ . ARG C 1 197 ? -58.052 -5.564 -110.943 1.00 41.02 ? 259 ARG B CZ 1 +ATOM 8045 N NH1 . ARG C 1 197 ? -58.536 -4.421 -111.409 1.00 38.00 ? 259 ARG B NH1 1 +ATOM 8046 N NH2 . ARG C 1 197 ? -58.186 -5.862 -109.661 1.00 50.83 ? 259 ARG B NH2 1 +ATOM 8047 N N . HIS C 1 198 ? -51.874 -5.911 -115.524 1.00 40.17 ? 260 HIS B N 1 +ATOM 8048 C CA . HIS C 1 198 ? -51.210 -5.468 -116.745 1.00 38.00 ? 260 HIS B CA 1 +ATOM 8049 C C . HIS C 1 198 ? -52.189 -5.338 -117.902 1.00 38.00 ? 260 HIS B C 1 +ATOM 8050 O O . HIS C 1 198 ? -52.143 -4.356 -118.651 1.00 38.00 ? 260 HIS B O 1 +ATOM 8051 C CB . HIS C 1 198 ? -50.096 -6.448 -117.109 1.00 38.00 ? 260 HIS B CB 1 +ATOM 8052 C CG . HIS C 1 198 ? -50.586 -7.832 -117.420 1.00 41.36 ? 260 HIS B CG 1 +ATOM 8053 N ND1 . HIS C 1 198 ? -51.535 -8.477 -116.656 1.00 44.48 ? 260 HIS B ND1 1 +ATOM 8054 C CD2 . HIS C 1 198 ? -50.261 -8.692 -118.415 1.00 41.96 ? 260 HIS B CD2 1 +ATOM 8055 C CE1 . HIS C 1 198 ? -51.773 -9.673 -117.164 1.00 39.00 ? 260 HIS B CE1 1 +ATOM 8056 N NE2 . HIS C 1 198 ? -51.012 -9.829 -118.231 1.00 40.10 ? 260 HIS B NE2 1 +ATOM 8057 N N . ASN C 1 199 ? -53.089 -6.308 -118.059 1.00 38.00 ? 261 ASN B N 1 +ATOM 8058 C CA . ASN C 1 199 ? -53.999 -6.296 -119.195 1.00 38.00 ? 261 ASN B CA 1 +ATOM 8059 C C . ASN C 1 199 ? -54.943 -5.103 -119.167 1.00 38.00 ? 261 ASN B C 1 +ATOM 8060 O O . ASN C 1 199 ? -55.492 -4.736 -120.213 1.00 38.17 ? 261 ASN B O 1 +ATOM 8061 C CB . ASN C 1 199 ? -54.792 -7.597 -119.234 1.00 38.00 ? 261 ASN B CB 1 +ATOM 8062 C CG . ASN C 1 199 ? -55.645 -7.782 -118.013 1.00 38.00 ? 261 ASN B CG 1 +ATOM 8063 O OD1 . ASN C 1 199 ? -55.165 -8.204 -116.963 1.00 38.74 ? 261 ASN B OD1 1 +ATOM 8064 N ND2 . ASN C 1 199 ? -56.927 -7.486 -118.143 1.00 38.00 ? 261 ASN B ND2 1 +ATOM 8065 N N . ALA C 1 200 ? -55.145 -4.486 -118.005 1.00 38.00 ? 262 ALA B N 1 +ATOM 8066 C CA . ALA C 1 200 ? -56.007 -3.313 -117.966 1.00 38.00 ? 262 ALA B CA 1 +ATOM 8067 C C . ALA C 1 200 ? -55.312 -2.097 -118.553 1.00 38.00 ? 262 ALA B C 1 +ATOM 8068 O O . ALA C 1 200 ? -55.933 -1.325 -119.288 1.00 38.00 ? 262 ALA B O 1 +ATOM 8069 C CB . ALA C 1 200 ? -56.445 -3.027 -116.531 1.00 38.00 ? 262 ALA B CB 1 +ATOM 8070 N N . GLU C 1 201 ? -54.014 -1.940 -118.278 1.00 38.00 ? 263 GLU B N 1 +ATOM 8071 C CA . GLU C 1 201 ? -53.258 -0.832 -118.858 1.00 38.46 ? 263 GLU B CA 1 +ATOM 8072 C C . GLU C 1 201 ? -53.256 -0.899 -120.378 1.00 39.52 ? 263 GLU B C 1 +ATOM 8073 O O . GLU C 1 201 ? -53.267 0.135 -121.055 1.00 39.13 ? 263 GLU B O 1 +ATOM 8074 C CB . GLU C 1 201 ? -51.825 -0.832 -118.333 1.00 41.82 ? 263 GLU B CB 1 +ATOM 8075 C CG . GLU C 1 201 ? -51.682 -0.387 -116.895 1.00 46.50 ? 263 GLU B CG 1 +ATOM 8076 C CD . GLU C 1 201 ? -51.659 1.124 -116.754 1.00 54.60 ? 263 GLU B CD 1 +ATOM 8077 O OE1 . GLU C 1 201 ? -51.195 1.803 -117.698 1.00 58.16 ? 263 GLU B OE1 1 +ATOM 8078 O OE2 . GLU C 1 201 ? -52.090 1.631 -115.695 1.00 54.30 ? 263 GLU B OE2 1 +ATOM 8079 N N . ILE C 1 202 ? -53.228 -2.109 -120.931 1.00 38.00 ? 264 ILE B N 1 +ATOM 8080 C CA . ILE C 1 202 ? -53.304 -2.264 -122.378 1.00 38.00 ? 264 ILE B CA 1 +ATOM 8081 C C . ILE C 1 202 ? -54.700 -1.915 -122.869 1.00 40.13 ? 264 ILE B C 1 +ATOM 8082 O O . ILE C 1 202 ? -54.883 -1.005 -123.686 1.00 39.24 ? 264 ILE B O 1 +ATOM 8083 C CB . ILE C 1 202 ? -52.913 -3.693 -122.782 1.00 38.00 ? 264 ILE B CB 1 +ATOM 8084 C CG1 . ILE C 1 202 ? -51.606 -4.081 -122.104 1.00 38.00 ? 264 ILE B CG1 1 +ATOM 8085 C CG2 . ILE C 1 202 ? -52.800 -3.799 -124.280 1.00 45.02 ? 264 ILE B CG2 1 +ATOM 8086 C CD1 . ILE C 1 202 ? -51.260 -5.530 -122.264 1.00 39.44 ? 264 ILE B CD1 1 +ATOM 8087 N N . ALA C 1 203 ? -55.711 -2.612 -122.344 1.00 43.29 ? 265 ALA B N 1 +ATOM 8088 C CA . ALA C 1 203 ? -57.077 -2.397 -122.805 1.00 40.46 ? 265 ALA B CA 1 +ATOM 8089 C C . ALA C 1 203 ? -57.517 -0.955 -122.602 1.00 38.00 ? 265 ALA B C 1 +ATOM 8090 O O . ALA C 1 203 ? -58.326 -0.439 -123.380 1.00 38.00 ? 265 ALA B O 1 +ATOM 8091 C CB . ALA C 1 203 ? -58.029 -3.352 -122.087 1.00 38.00 ? 265 ALA B CB 1 +ATOM 8092 N N . ALA C 1 204 ? -56.996 -0.287 -121.571 1.00 38.00 ? 266 ALA B N 1 +ATOM 8093 C CA . ALA C 1 204 ? -57.303 1.125 -121.392 1.00 38.00 ? 266 ALA B CA 1 +ATOM 8094 C C . ALA C 1 204 ? -56.760 1.960 -122.536 1.00 38.00 ? 266 ALA B C 1 +ATOM 8095 O O . ALA C 1 204 ? -57.332 3.003 -122.869 1.00 38.94 ? 266 ALA B O 1 +ATOM 8096 C CB . ALA C 1 204 ? -56.742 1.631 -120.068 1.00 38.00 ? 266 ALA B CB 1 +ATOM 8097 N N . PHE C 1 205 ? -55.654 1.534 -123.145 1.00 38.00 ? 267 PHE B N 1 +ATOM 8098 C CA . PHE C 1 205 ? -55.128 2.284 -124.277 1.00 38.00 ? 267 PHE B CA 1 +ATOM 8099 C C . PHE C 1 205 ? -55.998 2.096 -125.511 1.00 39.40 ? 267 PHE B C 1 +ATOM 8100 O O . PHE C 1 205 ? -56.314 3.064 -126.213 1.00 42.73 ? 267 PHE B O 1 +ATOM 8101 C CB . PHE C 1 205 ? -53.689 1.881 -124.565 1.00 38.00 ? 267 PHE B CB 1 +ATOM 8102 C CG . PHE C 1 205 ? -53.192 2.371 -125.884 1.00 38.00 ? 267 PHE B CG 1 +ATOM 8103 C CD1 . PHE C 1 205 ? -53.173 3.726 -126.170 1.00 38.00 ? 267 PHE B CD1 1 +ATOM 8104 C CD2 . PHE C 1 205 ? -52.760 1.480 -126.845 1.00 38.00 ? 267 PHE B CD2 1 +ATOM 8105 C CE1 . PHE C 1 205 ? -52.723 4.183 -127.390 1.00 38.00 ? 267 PHE B CE1 1 +ATOM 8106 C CE2 . PHE C 1 205 ? -52.308 1.930 -128.064 1.00 39.72 ? 267 PHE B CE2 1 +ATOM 8107 C CZ . PHE C 1 205 ? -52.288 3.285 -128.338 1.00 38.00 ? 267 PHE B CZ 1 +ATOM 8108 N N . HIS C 1 206 ? -56.387 0.855 -125.801 1.00 39.17 ? 268 HIS B N 1 +ATOM 8109 C CA . HIS C 1 206 ? -57.223 0.606 -126.969 1.00 38.00 ? 268 HIS B CA 1 +ATOM 8110 C C . HIS C 1 206 ? -58.571 1.300 -126.841 1.00 38.00 ? 268 HIS B C 1 +ATOM 8111 O O . HIS C 1 206 ? -59.087 1.849 -127.820 1.00 50.69 ? 268 HIS B O 1 +ATOM 8112 C CB . HIS C 1 206 ? -57.393 -0.896 -127.169 1.00 38.23 ? 268 HIS B CB 1 +ATOM 8113 C CG . HIS C 1 206 ? -56.120 -1.587 -127.536 1.00 40.69 ? 268 HIS B CG 1 +ATOM 8114 N ND1 . HIS C 1 206 ? -55.877 -2.078 -128.800 1.00 46.33 ? 268 HIS B ND1 1 +ATOM 8115 C CD2 . HIS C 1 206 ? -55.001 -1.832 -126.815 1.00 44.31 ? 268 HIS B CD2 1 +ATOM 8116 C CE1 . HIS C 1 206 ? -54.669 -2.614 -128.835 1.00 54.35 ? 268 HIS B CE1 1 +ATOM 8117 N NE2 . HIS C 1 206 ? -54.115 -2.474 -127.644 1.00 49.44 ? 268 HIS B NE2 1 +ATOM 8118 N N . LEU C 1 207 ? -59.153 1.301 -125.640 1.00 38.00 ? 269 LEU B N 1 +ATOM 8119 C CA . LEU C 1 207 ? -60.387 2.051 -125.428 1.00 38.00 ? 269 LEU B CA 1 +ATOM 8120 C C . LEU C 1 207 ? -60.160 3.543 -125.624 1.00 38.00 ? 269 LEU B C 1 +ATOM 8121 O O . LEU C 1 207 ? -61.038 4.249 -126.129 1.00 38.00 ? 269 LEU B O 1 +ATOM 8122 C CB . LEU C 1 207 ? -60.940 1.775 -124.037 1.00 38.96 ? 269 LEU B CB 1 +ATOM 8123 C CG . LEU C 1 207 ? -62.443 1.542 -123.916 1.00 38.00 ? 269 LEU B CG 1 +ATOM 8124 C CD1 . LEU C 1 207 ? -62.837 1.754 -122.476 1.00 48.19 ? 269 LEU B CD1 1 +ATOM 8125 C CD2 . LEU C 1 207 ? -63.250 2.443 -124.822 1.00 38.00 ? 269 LEU B CD2 1 +ATOM 8126 N N . ASP C 1 208 ? -58.996 4.046 -125.205 1.00 38.00 ? 270 ASP B N 1 +ATOM 8127 C CA . ASP C 1 208 ? -58.652 5.431 -125.499 1.00 38.00 ? 270 ASP B CA 1 +ATOM 8128 C C . ASP C 1 208 ? -58.582 5.656 -127.002 1.00 38.00 ? 270 ASP B C 1 +ATOM 8129 O O . ASP C 1 208 ? -59.047 6.684 -127.508 1.00 40.56 ? 270 ASP B O 1 +ATOM 8130 C CB . ASP C 1 208 ? -57.324 5.799 -124.835 1.00 38.00 ? 270 ASP B CB 1 +ATOM 8131 C CG . ASP C 1 208 ? -56.906 7.234 -125.105 1.00 38.00 ? 270 ASP B CG 1 +ATOM 8132 O OD1 . ASP C 1 208 ? -57.748 8.045 -125.524 1.00 38.00 ? 270 ASP B OD1 1 +ATOM 8133 O OD2 . ASP C 1 208 ? -55.720 7.554 -124.908 1.00 38.00 ? 270 ASP B OD2 1 +ATOM 8134 N N . ARG C 1 209 ? -58.014 4.698 -127.734 1.00 38.00 ? 271 ARG B N 1 +ATOM 8135 C CA . ARG C 1 209 ? -57.901 4.857 -129.177 1.00 38.00 ? 271 ARG B CA 1 +ATOM 8136 C C . ARG C 1 209 ? -59.260 4.736 -129.854 1.00 38.00 ? 271 ARG B C 1 +ATOM 8137 O O . ARG C 1 209 ? -59.562 5.491 -130.785 1.00 42.66 ? 271 ARG B O 1 +ATOM 8138 C CB . ARG C 1 209 ? -56.914 3.833 -129.735 1.00 38.00 ? 271 ARG B CB 1 +ATOM 8139 C CG . ARG C 1 209 ? -56.421 4.175 -131.115 1.00 38.00 ? 271 ARG B CG 1 +ATOM 8140 C CD . ARG C 1 209 ? -55.170 3.403 -131.508 1.00 38.77 ? 271 ARG B CD 1 +ATOM 8141 N NE . ARG C 1 209 ? -55.232 1.977 -131.206 1.00 43.99 ? 271 ARG B NE 1 +ATOM 8142 C CZ . ARG C 1 209 ? -54.194 1.156 -131.332 1.00 39.29 ? 271 ARG B CZ 1 +ATOM 8143 N NH1 . ARG C 1 209 ? -53.030 1.632 -131.750 1.00 38.00 ? 271 ARG B NH1 1 +ATOM 8144 N NH2 . ARG C 1 209 ? -54.312 -0.133 -131.038 1.00 38.00 ? 271 ARG B NH2 1 +ATOM 8145 N N . ILE C 1 210 ? -60.108 3.827 -129.368 1.00 38.02 ? 272 ILE B N 1 +ATOM 8146 C CA . ILE C 1 210 ? -61.415 3.602 -129.981 1.00 38.00 ? 272 ILE B CA 1 +ATOM 8147 C C . ILE C 1 210 ? -62.344 4.787 -129.726 1.00 38.00 ? 272 ILE B C 1 +ATOM 8148 O O . ILE C 1 210 ? -63.143 5.164 -130.591 1.00 38.00 ? 272 ILE B O 1 +ATOM 8149 C CB . ILE C 1 210 ? -62.018 2.277 -129.470 1.00 38.00 ? 272 ILE B CB 1 +ATOM 8150 C CG1 . ILE C 1 210 ? -61.671 1.112 -130.400 1.00 38.00 ? 272 ILE B CG1 1 +ATOM 8151 C CG2 . ILE C 1 210 ? -63.519 2.369 -129.370 1.00 41.88 ? 272 ILE B CG2 1 +ATOM 8152 C CD1 . ILE C 1 210 ? -60.211 0.767 -130.457 1.00 38.00 ? 272 ILE B CD1 1 +ATOM 8153 N N . LEU C 1 211 ? -62.269 5.386 -128.537 1.00 38.00 ? 273 LEU B N 1 +ATOM 8154 C CA . LEU C 1 211 ? -63.120 6.535 -128.246 1.00 38.15 ? 273 LEU B CA 1 +ATOM 8155 C C . LEU C 1 211 ? -62.663 7.802 -128.953 1.00 38.00 ? 273 LEU B C 1 +ATOM 8156 O O . LEU C 1 211 ? -63.414 8.782 -128.969 1.00 38.00 ? 273 LEU B O 1 +ATOM 8157 C CB . LEU C 1 211 ? -63.169 6.798 -126.736 1.00 45.54 ? 273 LEU B CB 1 +ATOM 8158 C CG . LEU C 1 211 ? -63.913 5.840 -125.802 1.00 38.00 ? 273 LEU B CG 1 +ATOM 8159 C CD1 . LEU C 1 211 ? -63.697 6.242 -124.364 1.00 38.00 ? 273 LEU B CD1 1 +ATOM 8160 C CD2 . LEU C 1 211 ? -65.390 5.806 -126.111 1.00 38.00 ? 273 LEU B CD2 1 +ATOM 8161 N N . ASP C 1 212 ? -61.473 7.796 -129.553 1.00 39.56 ? 274 ASP B N 1 +ATOM 8162 C CA . ASP C 1 212 ? -60.839 9.005 -130.087 1.00 50.96 ? 274 ASP B CA 1 +ATOM 8163 C C . ASP C 1 212 ? -60.647 10.066 -129.007 1.00 45.72 ? 274 ASP B C 1 +ATOM 8164 O O . ASP C 1 212 ? -60.666 11.267 -129.289 1.00 50.77 ? 274 ASP B O 1 +ATOM 8165 C CB . ASP C 1 212 ? -61.620 9.588 -131.273 1.00 56.99 ? 274 ASP B CB 1 +ATOM 8166 C CG . ASP C 1 212 ? -60.792 10.576 -132.096 1.00 63.58 ? 274 ASP B CG 1 +ATOM 8167 O OD1 . ASP C 1 212 ? -59.634 10.245 -132.433 1.00 64.14 ? 274 ASP B OD1 1 +ATOM 8168 O OD2 . ASP C 1 212 ? -61.299 11.680 -132.401 1.00 61.01 ? 274 ASP B OD2 1 +ATOM 8169 N N . PHE C 1 213 ? -60.449 9.639 -127.761 1.00 40.75 ? 275 PHE B N 1 +ATOM 8170 C CA . PHE C 1 213 ? -60.016 10.586 -126.742 1.00 46.89 ? 275 PHE B CA 1 +ATOM 8171 C C . PHE C 1 213 ? -58.553 10.950 -126.943 1.00 47.40 ? 275 PHE B C 1 +ATOM 8172 O O . PHE C 1 213 ? -58.183 12.129 -126.864 1.00 43.47 ? 275 PHE B O 1 +ATOM 8173 C CB . PHE C 1 213 ? -60.231 10.002 -125.346 1.00 49.33 ? 275 PHE B CB 1 +ATOM 8174 C CG . PHE C 1 213 ? -61.629 10.151 -124.829 1.00 45.49 ? 275 PHE B CG 1 +ATOM 8175 C CD1 . PHE C 1 213 ? -62.508 11.040 -125.413 1.00 49.45 ? 275 PHE B CD1 1 +ATOM 8176 C CD2 . PHE C 1 213 ? -62.072 9.369 -123.779 1.00 43.61 ? 275 PHE B CD2 1 +ATOM 8177 C CE1 . PHE C 1 213 ? -63.797 11.164 -124.939 1.00 51.91 ? 275 PHE B CE1 1 +ATOM 8178 C CE2 . PHE C 1 213 ? -63.355 9.485 -123.303 1.00 42.27 ? 275 PHE B CE2 1 +ATOM 8179 C CZ . PHE C 1 213 ? -64.222 10.384 -123.884 1.00 48.57 ? 275 PHE B CZ 1 +ATOM 8180 N N . ARG C 1 214 ? -57.714 9.948 -127.218 1.00 46.45 ? 276 ARG B N 1 +ATOM 8181 C CA . ARG C 1 214 ? -56.297 10.144 -127.515 1.00 42.54 ? 276 ARG B CA 1 +ATOM 8182 C C . ARG C 1 214 ? -55.599 10.850 -126.353 1.00 44.44 ? 276 ARG B C 1 +ATOM 8183 O O . ARG C 1 214 ? -55.121 11.980 -126.469 1.00 49.01 ? 276 ARG B O 1 +ATOM 8184 C CB . ARG C 1 214 ? -56.117 10.909 -128.835 1.00 49.45 ? 276 ARG B CB 1 +ATOM 8185 C CG . ARG C 1 214 ? -55.775 10.026 -130.036 1.00 49.32 ? 276 ARG B CG 1 +ATOM 8186 C CD . ARG C 1 214 ? -56.268 10.596 -131.368 1.00 43.60 ? 276 ARG B CD 1 +ATOM 8187 N NE . ARG C 1 214 ? -55.911 11.998 -131.557 1.00 44.06 ? 276 ARG B NE 1 +ATOM 8188 C CZ . ARG C 1 214 ? -56.789 12.996 -131.544 1.00 52.83 ? 276 ARG B CZ 1 +ATOM 8189 N NH1 . ARG C 1 214 ? -58.077 12.738 -131.357 1.00 55.82 ? 276 ARG B NH1 1 +ATOM 8190 N NH2 . ARG C 1 214 ? -56.382 14.247 -131.723 1.00 54.03 ? 276 ARG B NH2 1 +ATOM 8191 N N . ARG C 1 215 ? -55.590 10.176 -125.200 1.00 43.54 ? 277 ARG B N 1 +ATOM 8192 C CA . ARG C 1 215 ? -55.070 10.791 -123.980 1.00 40.76 ? 277 ARG B CA 1 +ATOM 8193 C C . ARG C 1 215 ? -54.206 9.875 -123.125 1.00 43.35 ? 277 ARG B C 1 +ATOM 8194 O O . ARG C 1 215 ? -53.369 10.391 -122.380 1.00 45.74 ? 277 ARG B O 1 +ATOM 8195 C CB . ARG C 1 215 ? -56.222 11.332 -123.129 1.00 39.25 ? 277 ARG B CB 1 +ATOM 8196 C CG . ARG C 1 215 ? -56.905 12.507 -123.778 1.00 44.09 ? 277 ARG B CG 1 +ATOM 8197 C CD . ARG C 1 215 ? -58.207 12.854 -123.117 1.00 46.06 ? 277 ARG B CD 1 +ATOM 8198 N NE . ARG C 1 215 ? -59.129 13.412 -124.100 1.00 51.70 ? 277 ARG B NE 1 +ATOM 8199 C CZ . ARG C 1 215 ? -60.296 13.962 -123.795 1.00 61.72 ? 277 ARG B CZ 1 +ATOM 8200 N NH1 . ARG C 1 215 ? -60.676 14.029 -122.526 1.00 76.96 ? 277 ARG B NH1 1 +ATOM 8201 N NH2 . ARG C 1 215 ? -61.076 14.447 -124.754 1.00 49.42 ? 277 ARG B NH2 1 +ATOM 8202 N N . VAL C 1 216 ? -54.356 8.555 -123.198 1.00 44.95 ? 278 VAL B N 1 +ATOM 8203 C CA . VAL C 1 216 ? -53.499 7.658 -122.425 1.00 39.78 ? 278 VAL B CA 1 +ATOM 8204 C C . VAL C 1 216 ? -52.287 7.306 -123.280 1.00 38.00 ? 278 VAL B C 1 +ATOM 8205 O O . VAL C 1 216 ? -52.382 7.295 -124.516 1.00 38.00 ? 278 VAL B O 1 +ATOM 8206 C CB . VAL C 1 216 ? -54.259 6.399 -121.969 1.00 38.00 ? 278 VAL B CB 1 +ATOM 8207 C CG1 . VAL C 1 216 ? -55.739 6.692 -121.809 1.00 38.00 ? 278 VAL B CG1 1 +ATOM 8208 C CG2 . VAL C 1 216 ? -54.038 5.256 -122.925 1.00 38.00 ? 278 VAL B CG2 1 +ATOM 8209 N N . PRO C 1 217 ? -51.130 7.031 -122.677 1.00 38.00 ? 279 PRO B N 1 +ATOM 8210 C CA . PRO C 1 217 ? -49.960 6.697 -123.482 1.00 38.00 ? 279 PRO B CA 1 +ATOM 8211 C C . PRO C 1 217 ? -50.106 5.327 -124.097 1.00 38.00 ? 279 PRO B C 1 +ATOM 8212 O O . PRO C 1 217 ? -50.763 4.434 -123.527 1.00 38.82 ? 279 PRO B O 1 +ATOM 8213 C CB . PRO C 1 217 ? -48.808 6.738 -122.459 1.00 42.73 ? 279 PRO B CB 1 +ATOM 8214 C CG . PRO C 1 217 ? -49.345 7.519 -121.297 1.00 38.00 ? 279 PRO B CG 1 +ATOM 8215 C CD . PRO C 1 217 ? -50.794 7.185 -121.254 1.00 38.00 ? 279 PRO B CD 1 +ATOM 8216 N N . PRO C 1 218 ? -49.527 5.096 -125.280 1.00 38.00 ? 280 PRO B N 1 +ATOM 8217 C CA . PRO C 1 218 ? -49.623 3.779 -125.919 1.00 40.05 ? 280 PRO B CA 1 +ATOM 8218 C C . PRO C 1 218 ? -49.064 2.670 -125.040 1.00 38.00 ? 280 PRO B C 1 +ATOM 8219 O O . PRO C 1 218 ? -48.071 2.848 -124.332 1.00 38.00 ? 280 PRO B O 1 +ATOM 8220 C CB . PRO C 1 218 ? -48.809 3.946 -127.206 1.00 38.00 ? 280 PRO B CB 1 +ATOM 8221 C CG . PRO C 1 218 ? -48.852 5.406 -127.481 1.00 39.66 ? 280 PRO B CG 1 +ATOM 8222 C CD . PRO C 1 218 ? -48.838 6.076 -126.136 1.00 38.00 ? 280 PRO B CD 1 +ATOM 8223 N N . THR C 1 219 ? -49.726 1.518 -125.080 1.00 38.00 ? 281 THR B N 1 +ATOM 8224 C CA . THR C 1 219 ? -49.369 0.411 -124.210 1.00 38.00 ? 281 THR B CA 1 +ATOM 8225 C C . THR C 1 219 ? -49.472 -0.901 -124.969 1.00 38.00 ? 281 THR B C 1 +ATOM 8226 O O . THR C 1 219 ? -50.481 -1.167 -125.629 1.00 38.00 ? 281 THR B O 1 +ATOM 8227 C CB . THR C 1 219 ? -50.274 0.392 -122.979 1.00 38.00 ? 281 THR B CB 1 +ATOM 8228 O OG1 . THR C 1 219 ? -50.187 1.657 -122.315 1.00 38.00 ? 281 THR B OG1 1 +ATOM 8229 C CG2 . THR C 1 219 ? -49.848 -0.697 -122.024 1.00 38.69 ? 281 THR B CG2 1 +ATOM 8230 N N . VAL C 1 220 ? -48.422 -1.712 -124.873 1.00 40.79 ? 282 VAL B N 1 +ATOM 8231 C CA . VAL C 1 220 ? -48.383 -3.022 -125.500 1.00 39.81 ? 282 VAL B CA 1 +ATOM 8232 C C . VAL C 1 220 ? -48.105 -4.053 -124.417 1.00 40.58 ? 282 VAL B C 1 +ATOM 8233 O O . VAL C 1 220 ? -47.577 -3.748 -123.345 1.00 38.00 ? 282 VAL B O 1 +ATOM 8234 C CB . VAL C 1 220 ? -47.333 -3.102 -126.637 1.00 38.00 ? 282 VAL B CB 1 +ATOM 8235 C CG1 . VAL C 1 220 ? -46.804 -1.730 -126.955 1.00 38.00 ? 282 VAL B CG1 1 +ATOM 8236 C CG2 . VAL C 1 220 ? -46.179 -4.026 -126.290 1.00 38.00 ? 282 VAL B CG2 1 +ATOM 8237 N N . GLY C 1 221 ? -48.487 -5.287 -124.705 1.00 47.08 ? 283 GLY B N 1 +ATOM 8238 C CA . GLY C 1 221 ? -48.130 -6.415 -123.876 1.00 42.02 ? 283 GLY B CA 1 +ATOM 8239 C C . GLY C 1 221 ? -46.906 -7.112 -124.437 1.00 42.67 ? 283 GLY B C 1 +ATOM 8240 O O . GLY C 1 221 ? -46.687 -7.139 -125.645 1.00 48.54 ? 283 GLY B O 1 +ATOM 8241 N N . ARG C 1 222 ? -46.091 -7.652 -123.541 1.00 38.00 ? 284 ARG B N 1 +ATOM 8242 C CA . ARG C 1 222 ? -44.861 -8.299 -123.955 1.00 38.00 ? 284 ARG B CA 1 +ATOM 8243 C C . ARG C 1 222 ? -44.470 -9.336 -122.924 1.00 38.00 ? 284 ARG B C 1 +ATOM 8244 O O . ARG C 1 222 ? -44.570 -9.093 -121.721 1.00 38.00 ? 284 ARG B O 1 +ATOM 8245 C CB . ARG C 1 222 ? -43.739 -7.283 -124.126 1.00 38.00 ? 284 ARG B CB 1 +ATOM 8246 C CG . ARG C 1 222 ? -42.373 -7.894 -124.233 1.00 38.00 ? 284 ARG B CG 1 +ATOM 8247 C CD . ARG C 1 222 ? -41.393 -6.833 -124.587 1.00 38.00 ? 284 ARG B CD 1 +ATOM 8248 N NE . ARG C 1 222 ? -40.042 -7.353 -124.687 1.00 38.00 ? 284 ARG B NE 1 +ATOM 8249 C CZ . ARG C 1 222 ? -39.005 -6.610 -125.043 1.00 38.00 ? 284 ARG B CZ 1 +ATOM 8250 N NH1 . ARG C 1 222 ? -39.187 -5.329 -125.333 1.00 38.00 ? 284 ARG B NH1 1 +ATOM 8251 N NH2 . ARG C 1 222 ? -37.792 -7.141 -125.112 1.00 43.45 ? 284 ARG B NH2 1 +ATOM 8252 N N . ILE C 1 223 ? -44.002 -10.474 -123.403 1.00 40.74 ? 285 ILE B N 1 +ATOM 8253 C CA . ILE C 1 223 ? -43.453 -11.505 -122.539 1.00 38.00 ? 285 ILE B CA 1 +ATOM 8254 C C . ILE C 1 223 ? -41.986 -11.175 -122.301 1.00 40.97 ? 285 ILE B C 1 +ATOM 8255 O O . ILE C 1 223 ? -41.238 -10.905 -123.250 1.00 39.37 ? 285 ILE B O 1 +ATOM 8256 C CB . ILE C 1 223 ? -43.626 -12.892 -123.170 1.00 38.00 ? 285 ILE B CB 1 +ATOM 8257 C CG1 . ILE C 1 223 ? -45.104 -13.140 -123.468 1.00 38.00 ? 285 ILE B CG1 1 +ATOM 8258 C CG2 . ILE C 1 223 ? -43.070 -13.959 -122.251 1.00 38.00 ? 285 ILE B CG2 1 +ATOM 8259 C CD1 . ILE C 1 223 ? -45.372 -14.455 -124.133 1.00 38.69 ? 285 ILE B CD1 1 +ATOM 8260 N N . VAL C 1 224 ? -41.582 -11.152 -121.033 1.00 39.53 ? 286 VAL B N 1 +ATOM 8261 C CA . VAL C 1 224 ? -40.262 -10.677 -120.631 1.00 45.39 ? 286 VAL B CA 1 +ATOM 8262 C C . VAL C 1 224 ? -39.486 -11.827 -119.995 1.00 42.84 ? 286 VAL B C 1 +ATOM 8263 O O . VAL C 1 224 ? -40.030 -12.561 -119.164 1.00 48.08 ? 286 VAL B O 1 +ATOM 8264 C CB . VAL C 1 224 ? -40.374 -9.489 -119.657 1.00 40.99 ? 286 VAL B CB 1 +ATOM 8265 C CG1 . VAL C 1 224 ? -38.998 -8.943 -119.313 1.00 38.85 ? 286 VAL B CG1 1 +ATOM 8266 C CG2 . VAL C 1 224 ? -41.257 -8.394 -120.240 1.00 38.00 ? 286 VAL B CG2 1 +ATOM 8267 N N . ASN C 1 225 ? -38.225 -11.997 -120.401 1.00 38.85 ? 287 ASN B N 1 +ATOM 8268 C CA . ASN C 1 225 ? -37.289 -12.872 -119.690 1.00 38.51 ? 287 ASN B CA 1 +ATOM 8269 C C . ASN C 1 225 ? -36.754 -12.046 -118.529 1.00 38.00 ? 287 ASN B C 1 +ATOM 8270 O O . ASN C 1 225 ? -35.854 -11.221 -118.702 1.00 40.99 ? 287 ASN B O 1 +ATOM 8271 C CB . ASN C 1 225 ? -36.173 -13.364 -120.616 1.00 49.65 ? 287 ASN B CB 1 +ATOM 8272 C CG . ASN C 1 225 ? -35.305 -14.486 -119.997 1.00 50.85 ? 287 ASN B CG 1 +ATOM 8273 O OD1 . ASN C 1 225 ? -35.142 -14.560 -118.781 1.00 54.06 ? 287 ASN B OD1 1 +ATOM 8274 N ND2 . ASN C 1 225 ? -34.745 -15.355 -120.850 1.00 38.00 ? 287 ASN B ND2 1 +ATOM 8275 N N . VAL C 1 226 ? -37.347 -12.237 -117.347 1.00 38.00 ? 288 VAL B N 1 +ATOM 8276 C CA . VAL C 1 226 ? -37.039 -11.399 -116.194 1.00 38.00 ? 288 VAL B CA 1 +ATOM 8277 C C . VAL C 1 226 ? -35.581 -11.504 -115.786 1.00 38.00 ? 288 VAL B C 1 +ATOM 8278 O O . VAL C 1 226 ? -35.053 -10.594 -115.140 1.00 38.00 ? 288 VAL B O 1 +ATOM 8279 C CB . VAL C 1 226 ? -37.965 -11.757 -115.019 1.00 38.00 ? 288 VAL B CB 1 +ATOM 8280 C CG1 . VAL C 1 226 ? -39.389 -11.369 -115.344 1.00 38.00 ? 288 VAL B CG1 1 +ATOM 8281 C CG2 . VAL C 1 226 ? -37.877 -13.235 -114.721 1.00 38.00 ? 288 VAL B CG2 1 +ATOM 8282 N N . THR C 1 227 ? -34.910 -12.594 -116.145 1.00 38.00 ? 289 THR B N 1 +ATOM 8283 C CA . THR C 1 227 ? -33.485 -12.688 -115.868 1.00 38.00 ? 289 THR B CA 1 +ATOM 8284 C C . THR C 1 227 ? -32.679 -11.914 -116.907 1.00 40.36 ? 289 THR B C 1 +ATOM 8285 O O . THR C 1 227 ? -31.817 -11.103 -116.555 1.00 40.21 ? 289 THR B O 1 +ATOM 8286 C CB . THR C 1 227 ? -33.043 -14.150 -115.825 1.00 38.00 ? 289 THR B CB 1 +ATOM 8287 O OG1 . THR C 1 227 ? -33.775 -14.842 -114.808 1.00 38.00 ? 289 THR B OG1 1 +ATOM 8288 C CG2 . THR C 1 227 ? -31.564 -14.230 -115.500 1.00 46.15 ? 289 THR B CG2 1 +ATOM 8289 N N . LYS C 1 228 ? -32.935 -12.168 -118.193 1.00 42.88 ? 290 LYS B N 1 +ATOM 8290 C CA . LYS C 1 228 ? -32.147 -11.552 -119.256 1.00 44.04 ? 290 LYS B CA 1 +ATOM 8291 C C . LYS C 1 228 ? -32.518 -10.095 -119.502 1.00 38.00 ? 290 LYS B C 1 +ATOM 8292 O O . LYS C 1 228 ? -31.649 -9.295 -119.863 1.00 38.00 ? 290 LYS B O 1 +ATOM 8293 C CB . LYS C 1 228 ? -32.315 -12.350 -120.553 1.00 49.07 ? 290 LYS B CB 1 +ATOM 8294 C CG . LYS C 1 228 ? -31.464 -11.860 -121.729 1.00 49.35 ? 290 LYS B CG 1 +ATOM 8295 C CD . LYS C 1 228 ? -31.772 -12.633 -123.013 1.00 53.34 ? 290 LYS B CD 1 +ATOM 8296 C CE . LYS C 1 228 ? -33.136 -12.247 -123.582 1.00 52.38 ? 290 LYS B CE 1 +ATOM 8297 N NZ . LYS C 1 228 ? -33.605 -13.139 -124.685 1.00 41.24 ? 290 LYS B NZ 1 +ATOM 8298 N N . GLU C 1 229 ? -33.776 -9.722 -119.293 1.00 38.00 ? 291 GLU B N 1 +ATOM 8299 C CA . GLU C 1 229 ? -34.247 -8.402 -119.685 1.00 38.34 ? 291 GLU B CA 1 +ATOM 8300 C C . GLU C 1 229 ? -34.504 -7.463 -118.517 1.00 38.00 ? 291 GLU B C 1 +ATOM 8301 O O . GLU C 1 229 ? -34.836 -6.295 -118.748 1.00 38.00 ? 291 GLU B O 1 +ATOM 8302 C CB . GLU C 1 229 ? -35.515 -8.527 -120.539 1.00 42.31 ? 291 GLU B CB 1 +ATOM 8303 C CG . GLU C 1 229 ? -35.230 -8.824 -122.002 1.00 45.53 ? 291 GLU B CG 1 +ATOM 8304 C CD . GLU C 1 229 ? -36.436 -9.356 -122.746 1.00 41.97 ? 291 GLU B CD 1 +ATOM 8305 O OE1 . GLU C 1 229 ? -37.425 -9.745 -122.093 1.00 38.00 ? 291 GLU B OE1 1 +ATOM 8306 O OE2 . GLU C 1 229 ? -36.397 -9.375 -123.991 1.00 48.95 ? 291 GLU B OE2 1 +ATOM 8307 N N . ILE C 1 230 ? -34.345 -7.923 -117.277 1.00 38.00 ? 292 ILE B N 1 +ATOM 8308 C CA . ILE C 1 230 ? -34.515 -7.056 -116.115 1.00 38.00 ? 292 ILE B CA 1 +ATOM 8309 C C . ILE C 1 230 ? -33.296 -7.156 -115.209 1.00 38.00 ? 292 ILE B C 1 +ATOM 8310 O O . ILE C 1 230 ? -32.565 -6.178 -115.023 1.00 38.00 ? 292 ILE B O 1 +ATOM 8311 C CB . ILE C 1 230 ? -35.796 -7.408 -115.336 1.00 38.00 ? 292 ILE B CB 1 +ATOM 8312 C CG1 . ILE C 1 230 ? -37.041 -7.170 -116.195 1.00 38.00 ? 292 ILE B CG1 1 +ATOM 8313 C CG2 . ILE C 1 230 ? -35.867 -6.598 -114.058 1.00 38.00 ? 292 ILE B CG2 1 +ATOM 8314 C CD1 . ILE C 1 230 ? -38.345 -7.528 -115.500 1.00 38.00 ? 292 ILE B CD1 1 +ATOM 8315 N N . LEU C 1 231 ? -33.041 -8.349 -114.674 1.00 38.00 ? 293 LEU B N 1 +ATOM 8316 C CA . LEU C 1 231 ? -31.984 -8.497 -113.681 1.00 38.00 ? 293 LEU B CA 1 +ATOM 8317 C C . LEU C 1 231 ? -30.609 -8.256 -114.291 1.00 38.00 ? 293 LEU B C 1 +ATOM 8318 O O . LEU C 1 231 ? -29.782 -7.539 -113.719 1.00 38.00 ? 293 LEU B O 1 +ATOM 8319 C CB . LEU C 1 231 ? -32.055 -9.883 -113.050 1.00 38.00 ? 293 LEU B CB 1 +ATOM 8320 C CG . LEU C 1 231 ? -30.897 -10.198 -112.111 1.00 38.00 ? 293 LEU B CG 1 +ATOM 8321 C CD1 . LEU C 1 231 ? -30.833 -9.193 -110.983 1.00 38.00 ? 293 LEU B CD1 1 +ATOM 8322 C CD2 . LEU C 1 231 ? -31.051 -11.601 -111.575 1.00 46.77 ? 293 LEU B CD2 1 +ATOM 8323 N N . GLU C 1 232 ? -30.342 -8.850 -115.447 1.00 38.00 ? 294 GLU B N 1 +ATOM 8324 C CA . GLU C 1 232 ? -29.023 -8.749 -116.057 1.00 38.88 ? 294 GLU B CA 1 +ATOM 8325 C C . GLU C 1 232 ? -28.767 -7.400 -116.722 1.00 38.00 ? 294 GLU B C 1 +ATOM 8326 O O . GLU C 1 232 ? -27.683 -7.200 -117.281 1.00 38.00 ? 294 GLU B O 1 +ATOM 8327 C CB . GLU C 1 232 ? -28.836 -9.888 -117.063 1.00 42.19 ? 294 GLU B CB 1 +ATOM 8328 C CG . GLU C 1 232 ? -28.690 -11.254 -116.403 1.00 42.97 ? 294 GLU B CG 1 +ATOM 8329 C CD . GLU C 1 232 ? -28.446 -12.368 -117.402 1.00 54.79 ? 294 GLU B CD 1 +ATOM 8330 O OE1 . GLU C 1 232 ? -28.102 -12.066 -118.565 1.00 55.94 ? 294 GLU B OE1 1 +ATOM 8331 O OE2 . GLU C 1 232 ? -28.602 -13.549 -117.023 1.00 60.15 ? 294 GLU B OE2 1 +ATOM 8332 N N . VAL C 1 233 ? -29.718 -6.469 -116.672 1.00 38.00 ? 295 VAL B N 1 +ATOM 8333 C CA . VAL C 1 233 ? -29.535 -5.144 -117.246 1.00 38.00 ? 295 VAL B CA 1 +ATOM 8334 C C . VAL C 1 233 ? -29.671 -4.031 -116.218 1.00 41.89 ? 295 VAL B C 1 +ATOM 8335 O O . VAL C 1 233 ? -29.543 -2.857 -116.579 1.00 43.34 ? 295 VAL B O 1 +ATOM 8336 C CB . VAL C 1 233 ? -30.489 -4.896 -118.433 1.00 38.00 ? 295 VAL B CB 1 +ATOM 8337 C CG1 . VAL C 1 233 ? -29.735 -5.046 -119.737 1.00 42.07 ? 295 VAL B CG1 1 +ATOM 8338 C CG2 . VAL C 1 233 ? -31.643 -5.854 -118.393 1.00 38.00 ? 295 VAL B CG2 1 +ATOM 8339 N N . THR C 1 234 ? -29.968 -4.352 -114.960 1.00 45.50 ? 296 THR B N 1 +ATOM 8340 C CA . THR C 1 234 ? -30.092 -3.333 -113.923 1.00 43.84 ? 296 THR B CA 1 +ATOM 8341 C C . THR C 1 234 ? -28.755 -3.053 -113.239 1.00 46.48 ? 296 THR B C 1 +ATOM 8342 O O . THR C 1 234 ? -28.033 -3.970 -112.835 1.00 45.03 ? 296 THR B O 1 +ATOM 8343 C CB . THR C 1 234 ? -31.129 -3.739 -112.875 1.00 38.00 ? 296 THR B CB 1 +ATOM 8344 O OG1 . THR C 1 234 ? -31.210 -2.716 -111.884 1.00 44.48 ? 296 THR B OG1 1 +ATOM 8345 C CG2 . THR C 1 234 ? -30.741 -5.036 -112.200 1.00 38.00 ? 296 THR B CG2 1 +ATOM 8346 N N . LYS C 1 235 ? -28.455 -1.769 -113.071 1.00 51.20 ? 297 LYS B N 1 +ATOM 8347 C CA . LYS C 1 235 ? -27.283 -1.328 -112.333 1.00 56.95 ? 297 LYS B CA 1 +ATOM 8348 C C . LYS C 1 235 ? -27.623 -1.016 -110.884 1.00 57.57 ? 297 LYS B C 1 +ATOM 8349 O O . LYS C 1 235 ? -26.733 -0.652 -110.108 1.00 62.41 ? 297 LYS B O 1 +ATOM 8350 C CB . LYS C 1 235 ? -26.680 -0.087 -113.006 1.00 67.81 ? 297 LYS B CB 1 +ATOM 8351 C CG . LYS C 1 235 ? -26.278 -0.291 -114.468 1.00 72.59 ? 297 LYS B CG 1 +ATOM 8352 C CD . LYS C 1 235 ? -25.744 0.998 -115.101 1.00 79.67 ? 297 LYS B CD 1 +ATOM 8353 C CE . LYS C 1 235 ? -25.514 0.864 -116.614 1.00 77.24 ? 297 LYS B CE 1 +ATOM 8354 N NZ . LYS C 1 235 ? -26.770 0.739 -117.414 1.00 55.82 ? 297 LYS B NZ 1 +ATOM 8355 N N . ASN C 1 236 ? -28.891 -1.168 -110.510 1.00 61.76 ? 298 ASN B N 1 +ATOM 8356 C CA . ASN C 1 236 ? -29.370 -0.825 -109.178 1.00 56.90 ? 298 ASN B CA 1 +ATOM 8357 C C . ASN C 1 236 ? -29.128 -1.978 -108.212 1.00 47.16 ? 298 ASN B C 1 +ATOM 8358 O O . ASN C 1 236 ? -29.655 -3.081 -108.404 1.00 40.59 ? 298 ASN B O 1 +ATOM 8359 C CB . ASN C 1 236 ? -30.855 -0.484 -109.241 1.00 51.76 ? 298 ASN B CB 1 +ATOM 8360 C CG . ASN C 1 236 ? -31.376 0.044 -107.943 1.00 41.36 ? 298 ASN B CG 1 +ATOM 8361 O OD1 . ASN C 1 236 ? -31.600 -0.722 -107.016 1.00 42.72 ? 298 ASN B OD1 1 +ATOM 8362 N ND2 . ASN C 1 236 ? -31.598 1.350 -107.867 1.00 41.82 ? 298 ASN B ND2 1 +ATOM 8363 N N . GLU C 1 237 ? -28.371 -1.702 -107.145 1.00 44.57 ? 299 GLU B N 1 +ATOM 8364 C CA . GLU C 1 237 ? -27.988 -2.755 -106.211 1.00 47.32 ? 299 GLU B CA 1 +ATOM 8365 C C . GLU C 1 237 ? -29.187 -3.296 -105.437 1.00 48.13 ? 299 GLU B C 1 +ATOM 8366 O O . GLU C 1 237 ? -29.172 -4.458 -105.013 1.00 53.59 ? 299 GLU B O 1 +ATOM 8367 C CB . GLU C 1 237 ? -26.910 -2.242 -105.247 1.00 46.04 ? 299 GLU B CB 1 +ATOM 8368 C CG . GLU C 1 237 ? -25.787 -1.427 -105.902 1.00 49.87 ? 299 GLU B CG 1 +ATOM 8369 C CD . GLU C 1 237 ? -24.492 -2.219 -106.036 1.00 55.89 ? 299 GLU B CD 1 +ATOM 8370 O OE1 . GLU C 1 237 ? -24.576 -3.427 -106.334 1.00 61.83 ? 299 GLU B OE1 1 +ATOM 8371 O OE2 . GLU C 1 237 ? -23.394 -1.642 -105.871 1.00 62.10 ? 299 GLU B OE2 1 +ATOM 8372 N N . ILE C 1 238 ? -30.231 -2.486 -105.244 1.00 43.80 ? 300 ILE B N 1 +ATOM 8373 C CA . ILE C 1 238 ? -31.426 -2.988 -104.572 1.00 40.41 ? 300 ILE B CA 1 +ATOM 8374 C C . ILE C 1 238 ? -32.190 -3.936 -105.477 1.00 41.21 ? 300 ILE B C 1 +ATOM 8375 O O . ILE C 1 238 ? -32.688 -4.975 -105.030 1.00 42.46 ? 300 ILE B O 1 +ATOM 8376 C CB . ILE C 1 238 ? -32.324 -1.835 -104.105 1.00 38.00 ? 300 ILE B CB 1 +ATOM 8377 C CG1 . ILE C 1 238 ? -31.480 -0.730 -103.486 1.00 38.00 ? 300 ILE B CG1 1 +ATOM 8378 C CG2 . ILE C 1 238 ? -33.386 -2.349 -103.150 1.00 38.00 ? 300 ILE B CG2 1 +ATOM 8379 C CD1 . ILE C 1 238 ? -32.286 0.453 -103.077 1.00 38.00 ? 300 ILE B CD1 1 +ATOM 8380 N N . LEU C 1 239 ? -32.340 -3.571 -106.751 1.00 41.89 ? 301 LEU B N 1 +ATOM 8381 C CA . LEU C 1 239 ? -33.103 -4.418 -107.655 1.00 42.24 ? 301 LEU B CA 1 +ATOM 8382 C C . LEU C 1 239 ? -32.460 -5.789 -107.796 1.00 42.99 ? 301 LEU B C 1 +ATOM 8383 O O . LEU C 1 239 ? -33.169 -6.795 -107.890 1.00 45.86 ? 301 LEU B O 1 +ATOM 8384 C CB . LEU C 1 239 ? -33.246 -3.742 -109.019 1.00 38.84 ? 301 LEU B CB 1 +ATOM 8385 C CG . LEU C 1 239 ? -34.322 -4.353 -109.916 1.00 38.00 ? 301 LEU B CG 1 +ATOM 8386 C CD1 . LEU C 1 239 ? -35.629 -4.460 -109.161 1.00 38.00 ? 301 LEU B CD1 1 +ATOM 8387 C CD2 . LEU C 1 239 ? -34.509 -3.531 -111.176 1.00 38.00 ? 301 LEU B CD2 1 +ATOM 8388 N N . GLN C 1 240 ? -31.128 -5.863 -107.744 1.00 40.49 ? 302 GLN B N 1 +ATOM 8389 C CA . GLN C 1 240 ? -30.479 -7.167 -107.789 1.00 42.40 ? 302 GLN B CA 1 +ATOM 8390 C C . GLN C 1 240 ? -30.761 -7.996 -106.543 1.00 43.67 ? 302 GLN B C 1 +ATOM 8391 O O . GLN C 1 240 ? -30.693 -9.229 -106.610 1.00 44.98 ? 302 GLN B O 1 +ATOM 8392 C CB . GLN C 1 240 ? -28.967 -7.006 -107.986 1.00 41.28 ? 302 GLN B CB 1 +ATOM 8393 C CG . GLN C 1 240 ? -28.594 -6.315 -109.285 1.00 47.39 ? 302 GLN B CG 1 +ATOM 8394 C CD . GLN C 1 240 ? -27.126 -5.954 -109.368 1.00 53.90 ? 302 GLN B CD 1 +ATOM 8395 O OE1 . GLN C 1 240 ? -26.627 -5.147 -108.586 1.00 49.97 ? 302 GLN B OE1 1 +ATOM 8396 N NE2 . GLN C 1 240 ? -26.428 -6.538 -110.336 1.00 63.34 ? 302 GLN B NE2 1 +ATOM 8397 N N . SER C 1 241 ? -31.085 -7.353 -105.418 1.00 47.23 ? 303 SER B N 1 +ATOM 8398 C CA . SER C 1 241 ? -31.288 -8.065 -104.159 1.00 53.16 ? 303 SER B CA 1 +ATOM 8399 C C . SER C 1 241 ? -32.684 -8.669 -104.021 1.00 49.11 ? 303 SER B C 1 +ATOM 8400 O O . SER C 1 241 ? -32.868 -9.581 -103.204 1.00 47.30 ? 303 SER B O 1 +ATOM 8401 C CB . SER C 1 241 ? -31.001 -7.129 -102.972 1.00 48.75 ? 303 SER B CB 1 +ATOM 8402 O OG . SER C 1 241 ? -32.087 -6.254 -102.711 1.00 39.63 ? 303 SER B OG 1 +ATOM 8403 N N . VAL C 1 242 ? -33.653 -8.207 -104.802 1.00 45.45 ? 304 VAL B N 1 +ATOM 8404 C CA . VAL C 1 242 ? -35.031 -8.657 -104.648 1.00 45.57 ? 304 VAL B CA 1 +ATOM 8405 C C . VAL C 1 242 ? -35.333 -9.812 -105.600 1.00 48.97 ? 304 VAL B C 1 +ATOM 8406 O O . VAL C 1 242 ? -36.481 -10.249 -105.717 1.00 46.69 ? 304 VAL B O 1 +ATOM 8407 C CB . VAL C 1 242 ? -36.011 -7.493 -104.860 1.00 40.17 ? 304 VAL B CB 1 +ATOM 8408 C CG1 . VAL C 1 242 ? -35.685 -6.369 -103.916 1.00 45.10 ? 304 VAL B CG1 1 +ATOM 8409 C CG2 . VAL C 1 242 ? -35.961 -7.025 -106.294 1.00 45.42 ? 304 VAL B CG2 1 +ATOM 8410 N N . PHE C 1 243 ? -34.314 -10.303 -106.299 1.00 45.79 ? 305 PHE B N 1 +ATOM 8411 C CA . PHE C 1 243 ? -34.471 -11.462 -107.166 1.00 42.05 ? 305 PHE B CA 1 +ATOM 8412 C C . PHE C 1 243 ? -34.026 -12.720 -106.439 1.00 44.90 ? 305 PHE B C 1 +ATOM 8413 O O . PHE C 1 243 ? -32.901 -12.785 -105.932 1.00 46.42 ? 305 PHE B O 1 +ATOM 8414 C CB . PHE C 1 243 ? -33.679 -11.296 -108.459 1.00 38.80 ? 305 PHE B CB 1 +ATOM 8415 C CG . PHE C 1 243 ? -34.396 -10.508 -109.490 1.00 38.00 ? 305 PHE B CG 1 +ATOM 8416 C CD1 . PHE C 1 243 ? -34.270 -9.138 -109.540 1.00 38.00 ? 305 PHE B CD1 1 +ATOM 8417 C CD2 . PHE C 1 243 ? -35.229 -11.137 -110.389 1.00 38.00 ? 305 PHE B CD2 1 +ATOM 8418 C CE1 . PHE C 1 243 ? -34.940 -8.408 -110.489 1.00 38.00 ? 305 PHE B CE1 1 +ATOM 8419 C CE2 . PHE C 1 243 ? -35.902 -10.420 -111.337 1.00 41.30 ? 305 PHE B CE2 1 +ATOM 8420 C CZ . PHE C 1 243 ? -35.760 -9.051 -111.392 1.00 42.76 ? 305 PHE B CZ 1 +ATOM 8421 N N . PHE C 1 244 ? -34.911 -13.714 -106.387 1.00 43.35 ? 306 PHE B N 1 +ATOM 8422 C CA . PHE C 1 244 ? -34.613 -14.982 -105.740 1.00 48.95 ? 306 PHE B CA 1 +ATOM 8423 C C . PHE C 1 244 ? -35.162 -16.123 -106.589 1.00 48.03 ? 306 PHE B C 1 +ATOM 8424 O O . PHE C 1 244 ? -35.726 -15.912 -107.667 1.00 43.10 ? 306 PHE B O 1 +ATOM 8425 C CB . PHE C 1 244 ? -35.191 -15.023 -104.322 1.00 56.10 ? 306 PHE B CB 1 +ATOM 8426 C CG . PHE C 1 244 ? -36.688 -14.968 -104.280 1.00 51.44 ? 306 PHE B CG 1 +ATOM 8427 C CD1 . PHE C 1 244 ? -37.346 -13.755 -104.266 1.00 50.80 ? 306 PHE B CD1 1 +ATOM 8428 C CD2 . PHE C 1 244 ? -37.435 -16.132 -104.238 1.00 49.76 ? 306 PHE B CD2 1 +ATOM 8429 C CE1 . PHE C 1 244 ? -38.724 -13.705 -104.222 1.00 54.14 ? 306 PHE B CE1 1 +ATOM 8430 C CE2 . PHE C 1 244 ? -38.809 -16.089 -104.194 1.00 46.58 ? 306 PHE B CE2 1 +ATOM 8431 C CZ . PHE C 1 244 ? -39.457 -14.873 -104.186 1.00 49.12 ? 306 PHE B CZ 1 +ATOM 8432 N N . VAL C 1 245 ? -35.031 -17.341 -106.070 1.00 48.90 ? 307 VAL B N 1 +ATOM 8433 C CA . VAL C 1 245 ? -35.448 -18.552 -106.765 1.00 43.85 ? 307 VAL B CA 1 +ATOM 8434 C C . VAL C 1 245 ? -36.451 -19.287 -105.886 1.00 44.55 ? 307 VAL B C 1 +ATOM 8435 O O . VAL C 1 245 ? -36.220 -19.465 -104.684 1.00 45.81 ? 307 VAL B O 1 +ATOM 8436 C CB . VAL C 1 245 ? -34.243 -19.452 -107.095 1.00 42.07 ? 307 VAL B CB 1 +ATOM 8437 C CG1 . VAL C 1 245 ? -34.696 -20.710 -107.807 1.00 39.35 ? 307 VAL B CG1 1 +ATOM 8438 C CG2 . VAL C 1 245 ? -33.231 -18.694 -107.930 1.00 41.04 ? 307 VAL B CG2 1 +ATOM 8439 N N . SER C 1 246 ? -37.551 -19.724 -106.489 1.00 44.16 ? 308 SER B N 1 +ATOM 8440 C CA . SER C 1 246 ? -38.617 -20.378 -105.755 1.00 45.17 ? 308 SER B CA 1 +ATOM 8441 C C . SER C 1 246 ? -38.258 -21.817 -105.435 1.00 45.12 ? 308 SER B C 1 +ATOM 8442 O O . SER C 1 246 ? -37.343 -22.389 -106.031 1.00 46.97 ? 308 SER B O 1 +ATOM 8443 C CB . SER C 1 246 ? -39.908 -20.374 -106.570 1.00 48.01 ? 308 SER B CB 1 +ATOM 8444 O OG . SER C 1 246 ? -40.465 -19.082 -106.670 1.00 59.07 ? 308 SER B OG 1 +ATOM 8445 N N . PRO C 1 247 ? -38.972 -22.433 -104.491 1.00 47.75 ? 309 PRO B N 1 +ATOM 8446 C CA . PRO C 1 247 ? -38.872 -23.890 -104.352 1.00 48.99 ? 309 PRO B CA 1 +ATOM 8447 C C . PRO C 1 247 ? -39.247 -24.617 -105.626 1.00 53.87 ? 309 PRO B C 1 +ATOM 8448 O O . PRO C 1 247 ? -38.798 -25.749 -105.835 1.00 62.81 ? 309 PRO B O 1 +ATOM 8449 C CB . PRO C 1 247 ? -39.859 -24.203 -103.222 1.00 44.19 ? 309 PRO B CB 1 +ATOM 8450 C CG . PRO C 1 247 ? -39.929 -22.950 -102.431 1.00 46.07 ? 309 PRO B CG 1 +ATOM 8451 C CD . PRO C 1 247 ? -39.782 -21.830 -103.418 1.00 45.67 ? 309 PRO B CD 1 +ATOM 8452 N N . ALA C 1 248 ? -40.027 -23.987 -106.502 1.00 47.31 ? 310 ALA B N 1 +ATOM 8453 C CA . ALA C 1 248 ? -40.341 -24.540 -107.809 1.00 50.48 ? 310 ALA B CA 1 +ATOM 8454 C C . ALA C 1 248 ? -39.297 -24.183 -108.852 1.00 49.53 ? 310 ALA B C 1 +ATOM 8455 O O . ALA C 1 248 ? -39.495 -24.476 -110.036 1.00 47.81 ? 310 ALA B O 1 +ATOM 8456 C CB . ALA C 1 248 ? -41.720 -24.068 -108.269 1.00 55.04 ? 310 ALA B CB 1 +ATOM 8457 N N . SER C 1 249 ? -38.200 -23.551 -108.436 1.00 49.34 ? 311 SER B N 1 +ATOM 8458 C CA . SER C 1 249 ? -37.092 -23.209 -109.323 1.00 50.09 ? 311 SER B CA 1 +ATOM 8459 C C . SER C 1 249 ? -37.536 -22.204 -110.385 1.00 44.93 ? 311 SER B C 1 +ATOM 8460 O O . SER C 1 249 ? -37.333 -22.395 -111.585 1.00 44.74 ? 311 SER B O 1 +ATOM 8461 C CB . SER C 1 249 ? -36.496 -24.468 -109.957 1.00 51.53 ? 311 SER B CB 1 +ATOM 8462 O OG . SER C 1 249 ? -36.240 -25.445 -108.961 1.00 56.43 ? 311 SER B OG 1 +ATOM 8463 N N . ASN C 1 250 ? -38.145 -21.117 -109.922 1.00 44.80 ? 312 ASN B N 1 +ATOM 8464 C CA . ASN C 1 250 ? -38.593 -20.026 -110.773 1.00 43.00 ? 312 ASN B CA 1 +ATOM 8465 C C . ASN C 1 250 ? -37.919 -18.729 -110.348 1.00 42.75 ? 312 ASN B C 1 +ATOM 8466 O O . ASN C 1 250 ? -37.738 -18.474 -109.153 1.00 47.07 ? 312 ASN B O 1 +ATOM 8467 C CB . ASN C 1 250 ? -40.116 -19.868 -110.711 1.00 44.53 ? 312 ASN B CB 1 +ATOM 8468 C CG . ASN C 1 250 ? -40.850 -21.072 -111.269 1.00 51.09 ? 312 ASN B CG 1 +ATOM 8469 O OD1 . ASN C 1 250 ? -40.311 -21.809 -112.090 1.00 55.90 ? 312 ASN B OD1 1 +ATOM 8470 N ND2 . ASN C 1 250 ? -42.089 -21.270 -110.833 1.00 54.48 ? 312 ASN B ND2 1 +ATOM 8471 N N . VAL C 1 251 ? -37.528 -17.921 -111.327 1.00 38.00 ? 313 VAL B N 1 +ATOM 8472 C CA . VAL C 1 251 ? -36.956 -16.611 -111.039 1.00 38.00 ? 313 VAL B CA 1 +ATOM 8473 C C . VAL C 1 251 ? -38.091 -15.667 -110.680 1.00 38.26 ? 313 VAL B C 1 +ATOM 8474 O O . VAL C 1 251 ? -38.979 -15.411 -111.498 1.00 39.32 ? 313 VAL B O 1 +ATOM 8475 C CB . VAL C 1 251 ? -36.150 -16.071 -112.225 1.00 41.46 ? 313 VAL B CB 1 +ATOM 8476 C CG1 . VAL C 1 251 ? -35.678 -14.660 -111.920 1.00 42.32 ? 313 VAL B CG1 1 +ATOM 8477 C CG2 . VAL C 1 251 ? -34.967 -16.976 -112.524 1.00 52.40 ? 313 VAL B CG2 1 +ATOM 8478 N N . CYS C 1 252 ? -38.076 -15.168 -109.449 1.00 45.09 ? 314 CYS B N 1 +ATOM 8479 C CA . CYS C 1 252 ? -39.105 -14.275 -108.950 1.00 44.83 ? 314 CYS B CA 1 +ATOM 8480 C C . CYS C 1 252 ? -38.479 -12.972 -108.478 1.00 44.34 ? 314 CYS B C 1 +ATOM 8481 O O . CYS C 1 252 ? -37.292 -12.906 -108.144 1.00 46.73 ? 314 CYS B O 1 +ATOM 8482 C CB . CYS C 1 252 ? -39.871 -14.910 -107.794 1.00 47.12 ? 314 CYS B CB 1 +ATOM 8483 S SG . CYS C 1 252 ? -40.324 -16.626 -108.063 1.00 59.48 ? 314 CYS B SG 1 +ATOM 8484 N N . PHE C 1 253 ? -39.305 -11.934 -108.438 1.00 38.77 ? 315 PHE B N 1 +ATOM 8485 C CA . PHE C 1 253 ? -38.919 -10.668 -107.840 1.00 39.44 ? 315 PHE B CA 1 +ATOM 8486 C C . PHE C 1 253 ? -40.170 -10.049 -107.241 1.00 38.28 ? 315 PHE B C 1 +ATOM 8487 O O . PHE C 1 253 ? -41.287 -10.514 -107.476 1.00 42.84 ? 315 PHE B O 1 +ATOM 8488 C CB . PHE C 1 253 ? -38.231 -9.740 -108.851 1.00 42.49 ? 315 PHE B CB 1 +ATOM 8489 C CG . PHE C 1 253 ? -39.143 -9.188 -109.922 1.00 45.47 ? 315 PHE B CG 1 +ATOM 8490 C CD1 . PHE C 1 253 ? -39.952 -10.020 -110.685 1.00 46.43 ? 315 PHE B CD1 1 +ATOM 8491 C CD2 . PHE C 1 253 ? -39.173 -7.825 -110.177 1.00 41.70 ? 315 PHE B CD2 1 +ATOM 8492 C CE1 . PHE C 1 253 ? -40.779 -9.498 -111.671 1.00 41.62 ? 315 PHE B CE1 1 +ATOM 8493 C CE2 . PHE C 1 253 ? -39.994 -7.300 -111.158 1.00 42.56 ? 315 PHE B CE2 1 +ATOM 8494 C CZ . PHE C 1 253 ? -40.798 -8.139 -111.906 1.00 43.92 ? 315 PHE B CZ 1 +ATOM 8495 N N . PHE C 1 254 ? -39.975 -8.994 -106.455 1.00 39.06 ? 316 PHE B N 1 +ATOM 8496 C CA . PHE C 1 254 ? -41.055 -8.463 -105.636 1.00 45.27 ? 316 PHE B CA 1 +ATOM 8497 C C . PHE C 1 254 ? -40.806 -6.992 -105.351 1.00 49.30 ? 316 PHE B C 1 +ATOM 8498 O O . PHE C 1 254 ? -39.694 -6.485 -105.524 1.00 48.20 ? 316 PHE B O 1 +ATOM 8499 C CB . PHE C 1 254 ? -41.181 -9.235 -104.316 1.00 46.51 ? 316 PHE B CB 1 +ATOM 8500 C CG . PHE C 1 254 ? -39.918 -9.230 -103.485 1.00 49.07 ? 316 PHE B CG 1 +ATOM 8501 C CD1 . PHE C 1 254 ? -39.651 -8.197 -102.597 1.00 51.14 ? 316 PHE B CD1 1 +ATOM 8502 C CD2 . PHE C 1 254 ? -38.994 -10.253 -103.604 1.00 48.30 ? 316 PHE B CD2 1 +ATOM 8503 C CE1 . PHE C 1 254 ? -38.495 -8.192 -101.838 1.00 45.55 ? 316 PHE B CE1 1 +ATOM 8504 C CE2 . PHE C 1 254 ? -37.835 -10.252 -102.849 1.00 51.64 ? 316 PHE B CE2 1 +ATOM 8505 C CZ . PHE C 1 254 ? -37.585 -9.219 -101.966 1.00 47.81 ? 316 PHE B CZ 1 +ATOM 8506 N N . ALA C 1 255 ? -41.856 -6.312 -104.893 1.00 43.37 ? 317 ALA B N 1 +ATOM 8507 C CA . ALA C 1 255 ? -41.706 -4.959 -104.378 1.00 49.37 ? 317 ALA B CA 1 +ATOM 8508 C C . ALA C 1 255 ? -41.197 -5.015 -102.940 1.00 58.91 ? 317 ALA B C 1 +ATOM 8509 O O . ALA C 1 255 ? -41.729 -5.765 -102.113 1.00 57.70 ? 317 ALA B O 1 +ATOM 8510 C CB . ALA C 1 255 ? -43.032 -4.208 -104.452 1.00 47.12 ? 317 ALA B CB 1 +ATOM 8511 N N . LYS C 1 256 ? -40.171 -4.209 -102.642 1.00 60.61 ? 318 LYS B N 1 +ATOM 8512 C CA . LYS C 1 256 ? -39.463 -4.333 -101.368 1.00 49.64 ? 318 LYS B CA 1 +ATOM 8513 C C . LYS C 1 256 ? -40.398 -4.099 -100.191 1.00 44.84 ? 318 LYS B C 1 +ATOM 8514 O O . LYS C 1 256 ? -40.435 -4.894 -99.247 1.00 48.17 ? 318 LYS B O 1 +ATOM 8515 C CB . LYS C 1 256 ? -38.288 -3.352 -101.321 1.00 52.45 ? 318 LYS B CB 1 +ATOM 8516 C CG . LYS C 1 256 ? -37.335 -3.524 -100.139 1.00 49.15 ? 318 LYS B CG 1 +ATOM 8517 C CD . LYS C 1 256 ? -36.300 -4.616 -100.417 1.00 58.56 ? 318 LYS B CD 1 +ATOM 8518 C CE . LYS C 1 256 ? -35.287 -4.768 -99.280 1.00 54.93 ? 318 LYS B CE 1 +ATOM 8519 N NZ . LYS C 1 256 ? -34.282 -5.841 -99.561 1.00 53.04 ? 318 LYS B NZ 1 +ATOM 8520 N N . CYS C 1 257 ? -41.177 -3.015 -100.238 1.00 48.49 ? 319 CYS B N 1 +ATOM 8521 C CA . CYS C 1 257 ? -42.014 -2.673 -99.088 1.00 60.69 ? 319 CYS B CA 1 +ATOM 8522 C C . CYS C 1 257 ? -43.210 -3.610 -98.941 1.00 56.15 ? 319 CYS B C 1 +ATOM 8523 O O . CYS C 1 257 ? -43.400 -4.162 -97.843 1.00 61.34 ? 319 CYS B O 1 +ATOM 8524 C CB . CYS C 1 257 ? -42.424 -1.195 -99.171 1.00 62.24 ? 319 CYS B CB 1 +ATOM 8525 S SG . CYS C 1 257 ? -43.460 -0.539 -97.814 1.00 67.44 ? 319 CYS B SG 1 +ATOM 8526 N N . PRO C 1 258 ? -44.037 -3.848 -99.965 1.00 49.32 ? 320 PRO B N 1 +ATOM 8527 C CA . PRO C 1 258 ? -45.185 -4.742 -99.757 1.00 45.11 ? 320 PRO B CA 1 +ATOM 8528 C C . PRO C 1 258 ? -44.807 -6.155 -99.356 1.00 51.08 ? 320 PRO B C 1 +ATOM 8529 O O . PRO C 1 258 ? -45.559 -6.783 -98.603 1.00 59.48 ? 320 PRO B O 1 +ATOM 8530 C CB . PRO C 1 258 ? -45.899 -4.713 -101.110 1.00 48.86 ? 320 PRO B CB 1 +ATOM 8531 C CG . PRO C 1 258 ? -45.536 -3.420 -101.678 1.00 54.32 ? 320 PRO B CG 1 +ATOM 8532 C CD . PRO C 1 258 ? -44.115 -3.187 -101.276 1.00 54.15 ? 320 PRO B CD 1 +ATOM 8533 N N . TYR C 1 259 ? -43.685 -6.694 -99.842 1.00 51.64 ? 321 TYR B N 1 +ATOM 8534 C CA . TYR C 1 259 ? -43.281 -8.024 -99.392 1.00 57.92 ? 321 TYR B CA 1 +ATOM 8535 C C . TYR C 1 259 ? -42.932 -8.014 -97.905 1.00 63.23 ? 321 TYR B C 1 +ATOM 8536 O O . TYR C 1 259 ? -43.287 -8.945 -97.173 1.00 57.92 ? 321 TYR B O 1 +ATOM 8537 C CB . TYR C 1 259 ? -42.109 -8.549 -100.230 1.00 53.72 ? 321 TYR B CB 1 +ATOM 8538 C CG . TYR C 1 259 ? -41.850 -10.044 -100.087 1.00 51.63 ? 321 TYR B CG 1 +ATOM 8539 C CD1 . TYR C 1 259 ? -42.770 -10.879 -99.465 1.00 56.53 ? 321 TYR B CD1 1 +ATOM 8540 C CD2 . TYR C 1 259 ? -40.667 -10.611 -100.539 1.00 53.13 ? 321 TYR B CD2 1 +ATOM 8541 C CE1 . TYR C 1 259 ? -42.527 -12.237 -99.316 1.00 62.26 ? 321 TYR B CE1 1 +ATOM 8542 C CE2 . TYR C 1 259 ? -40.414 -11.969 -100.395 1.00 60.54 ? 321 TYR B CE2 1 +ATOM 8543 C CZ . TYR C 1 259 ? -41.349 -12.777 -99.782 1.00 62.43 ? 321 TYR B CZ 1 +ATOM 8544 O OH . TYR C 1 259 ? -41.111 -14.127 -99.626 1.00 58.23 ? 321 TYR B OH 1 +ATOM 8545 N N . MET C 1 260 ? -42.250 -6.966 -97.436 1.00 65.32 ? 322 MET B N 1 +ATOM 8546 C CA . MET C 1 260 ? -41.899 -6.887 -96.020 1.00 67.49 ? 322 MET B CA 1 +ATOM 8547 C C . MET C 1 260 ? -43.143 -6.870 -95.142 1.00 63.61 ? 322 MET B C 1 +ATOM 8548 O O . MET C 1 260 ? -43.212 -7.577 -94.130 1.00 72.90 ? 322 MET B O 1 +ATOM 8549 C CB . MET C 1 260 ? -41.045 -5.649 -95.759 1.00 71.69 ? 322 MET B CB 1 +ATOM 8550 C CG . MET C 1 260 ? -40.927 -5.277 -94.293 1.00 75.71 ? 322 MET B CG 1 +ATOM 8551 S SD . MET C 1 260 ? -39.539 -4.176 -94.012 1.00 115.48 ? 322 MET B SD 1 +ATOM 8552 C CE . MET C 1 260 ? -39.586 -3.200 -95.513 1.00 71.14 ? 322 MET B CE 1 +ATOM 8553 N N . CYS C 1 261 ? -44.139 -6.070 -95.515 1.00 54.91 ? 323 CYS B N 1 +ATOM 8554 C CA . CYS C 1 261 ? -45.393 -6.025 -94.776 1.00 57.69 ? 323 CYS B CA 1 +ATOM 8555 C C . CYS C 1 261 ? -46.301 -7.207 -95.087 1.00 57.11 ? 323 CYS B C 1 +ATOM 8556 O O . CYS C 1 261 ? -47.402 -7.282 -94.529 1.00 58.57 ? 323 CYS B O 1 +ATOM 8557 C CB . CYS C 1 261 ? -46.128 -4.716 -95.068 1.00 57.98 ? 323 CYS B CB 1 +ATOM 8558 S SG . CYS C 1 261 ? -45.272 -3.242 -94.481 1.00 68.37 ? 323 CYS B SG 1 +ATOM 8559 N N . LYS C 1 262 ? -45.877 -8.108 -95.976 1.00 54.67 ? 324 LYS B N 1 +ATOM 8560 C CA . LYS C 1 262 ? -46.655 -9.292 -96.339 1.00 52.29 ? 324 LYS B CA 1 +ATOM 8561 C C . LYS C 1 262 ? -48.060 -8.916 -96.795 1.00 53.30 ? 324 LYS B C 1 +ATOM 8562 O O . LYS C 1 262 ? -49.028 -9.631 -96.527 1.00 57.00 ? 324 LYS B O 1 +ATOM 8563 C CB . LYS C 1 262 ? -46.710 -10.300 -95.188 1.00 51.63 ? 324 LYS B CB 1 +ATOM 8564 C CG . LYS C 1 262 ? -45.345 -10.696 -94.649 1.00 59.35 ? 324 LYS B CG 1 +ATOM 8565 C CD . LYS C 1 262 ? -44.524 -11.466 -95.677 1.00 62.74 ? 324 LYS B CD 1 +ATOM 8566 C CE . LYS C 1 262 ? -43.050 -11.518 -95.274 1.00 65.51 ? 324 LYS B CE 1 +ATOM 8567 N NZ . LYS C 1 262 ? -42.278 -12.588 -95.979 1.00 63.07 ? 324 LYS B NZ 1 +ATOM 8568 N N . THR C 1 263 ? -48.182 -7.773 -97.468 1.00 50.52 ? 325 THR B N 1 +ATOM 8569 C CA . THR C 1 263 ? -49.451 -7.375 -98.059 1.00 52.38 ? 325 THR B CA 1 +ATOM 8570 C C . THR C 1 263 ? -49.629 -7.932 -99.467 1.00 54.22 ? 325 THR B C 1 +ATOM 8571 O O . THR C 1 263 ? -50.765 -8.175 -99.892 1.00 50.47 ? 325 THR B O 1 +ATOM 8572 C CB . THR C 1 263 ? -49.578 -5.843 -98.067 1.00 51.43 ? 325 THR B CB 1 +ATOM 8573 O OG1 . THR C 1 263 ? -50.250 -5.412 -99.257 1.00 57.99 ? 325 THR B OG1 1 +ATOM 8574 C CG2 . THR C 1 263 ? -48.223 -5.181 -97.991 1.00 50.28 ? 325 THR B CG2 1 +ATOM 8575 N N . GLU C 1 264 ? -48.536 -8.172 -100.189 1.00 55.23 ? 326 GLU B N 1 +ATOM 8576 C CA . GLU C 1 264 ? -48.598 -8.814 -101.492 1.00 52.64 ? 326 GLU B CA 1 +ATOM 8577 C C . GLU C 1 264 ? -47.495 -9.865 -101.578 1.00 54.33 ? 326 GLU B C 1 +ATOM 8578 O O . GLU C 1 264 ? -46.638 -9.974 -100.695 1.00 44.26 ? 326 GLU B O 1 +ATOM 8579 C CB . GLU C 1 264 ? -48.494 -7.778 -102.618 1.00 50.21 ? 326 GLU B CB 1 +ATOM 8580 C CG . GLU C 1 264 ? -47.078 -7.394 -102.960 1.00 56.28 ? 326 GLU B CG 1 +ATOM 8581 C CD . GLU C 1 264 ? -46.990 -6.445 -104.139 1.00 58.25 ? 326 GLU B CD 1 +ATOM 8582 O OE1 . GLU C 1 264 ? -47.879 -5.579 -104.284 1.00 56.45 ? 326 GLU B OE1 1 +ATOM 8583 O OE2 . GLU C 1 264 ? -46.030 -6.575 -104.929 1.00 59.83 ? 326 GLU B OE2 1 +ATOM 8584 N N . TYR C 1 265 ? -47.521 -10.647 -102.657 1.00 60.73 ? 327 TYR B N 1 +ATOM 8585 C CA . TYR C 1 265 ? -46.564 -11.725 -102.856 1.00 55.92 ? 327 TYR B CA 1 +ATOM 8586 C C . TYR C 1 265 ? -45.506 -11.314 -103.878 1.00 55.48 ? 327 TYR B C 1 +ATOM 8587 O O . TYR C 1 265 ? -45.416 -10.146 -104.272 1.00 57.72 ? 327 TYR B O 1 +ATOM 8588 C CB . TYR C 1 265 ? -47.300 -12.992 -103.311 1.00 55.78 ? 327 TYR B CB 1 +ATOM 8589 C CG . TYR C 1 265 ? -48.396 -13.466 -102.387 1.00 61.10 ? 327 TYR B CG 1 +ATOM 8590 C CD1 . TYR C 1 265 ? -48.294 -13.310 -101.011 1.00 66.71 ? 327 TYR B CD1 1 +ATOM 8591 C CD2 . TYR C 1 265 ? -49.539 -14.072 -102.897 1.00 55.63 ? 327 TYR B CD2 1 +ATOM 8592 C CE1 . TYR C 1 265 ? -49.302 -13.747 -100.168 1.00 62.41 ? 327 TYR B CE1 1 +ATOM 8593 C CE2 . TYR C 1 265 ? -50.548 -14.510 -102.065 1.00 51.52 ? 327 TYR B CE2 1 +ATOM 8594 C CZ . TYR C 1 265 ? -50.426 -14.346 -100.704 1.00 55.09 ? 327 TYR B CZ 1 +ATOM 8595 O OH . TYR C 1 265 ? -51.438 -14.787 -99.886 1.00 53.14 ? 327 TYR B OH 1 +ATOM 8596 N N . ALA C 1 266 ? -44.739 -12.282 -104.356 1.00 51.06 ? 328 ALA B N 1 +ATOM 8597 C CA . ALA C 1 266 ? -43.785 -12.046 -105.422 1.00 45.23 ? 328 ALA B CA 1 +ATOM 8598 C C . ALA C 1 266 ? -44.446 -12.381 -106.751 1.00 49.59 ? 328 ALA B C 1 +ATOM 8599 O O . ALA C 1 266 ? -45.560 -12.906 -106.807 1.00 53.08 ? 328 ALA B O 1 +ATOM 8600 C CB . ALA C 1 266 ? -42.515 -12.877 -105.214 1.00 38.00 ? 328 ALA B CB 1 +ATOM 8601 N N . VAL C 1 267 ? -43.740 -12.070 -107.829 1.00 46.65 ? 329 VAL B N 1 +ATOM 8602 C CA . VAL C 1 267 ? -44.211 -12.310 -109.184 1.00 38.00 ? 329 VAL B CA 1 +ATOM 8603 C C . VAL C 1 267 ? -43.171 -13.201 -109.830 1.00 38.00 ? 329 VAL B C 1 +ATOM 8604 O O . VAL C 1 267 ? -42.017 -12.789 -109.994 1.00 41.44 ? 329 VAL B O 1 +ATOM 8605 C CB . VAL C 1 267 ? -44.401 -11.013 -109.978 1.00 38.00 ? 329 VAL B CB 1 +ATOM 8606 C CG1 . VAL C 1 267 ? -44.897 -11.325 -111.364 1.00 48.10 ? 329 VAL B CG1 1 +ATOM 8607 C CG2 . VAL C 1 267 ? -45.385 -10.099 -109.274 1.00 42.39 ? 329 VAL B CG2 1 +ATOM 8608 N N . CYS C 1 268 ? -43.536 -14.449 -110.093 1.00 40.80 ? 330 CYS B N 1 +ATOM 8609 C CA . CYS C 1 268 ? -42.603 -15.421 -110.643 1.00 49.94 ? 330 CYS B CA 1 +ATOM 8610 C C . CYS C 1 268 ? -42.820 -15.657 -112.130 1.00 51.13 ? 330 CYS B C 1 +ATOM 8611 O O . CYS C 1 268 ? -43.948 -15.642 -112.628 1.00 62.87 ? 330 CYS B O 1 +ATOM 8612 C CB . CYS C 1 268 ? -42.714 -16.753 -109.913 1.00 50.27 ? 330 CYS B CB 1 +ATOM 8613 S SG . CYS C 1 268 ? -42.352 -16.638 -108.175 1.00 64.67 ? 330 CYS B SG 1 +ATOM 8614 N N . GLY C 1 269 ? -41.720 -15.914 -112.831 1.00 39.94 ? 331 GLY B N 1 +ATOM 8615 C CA . GLY C 1 269 ? -41.788 -16.465 -114.164 1.00 48.72 ? 331 GLY B CA 1 +ATOM 8616 C C . GLY C 1 269 ? -42.022 -17.965 -114.143 1.00 50.47 ? 331 GLY B C 1 +ATOM 8617 O O . GLY C 1 269 ? -42.157 -18.596 -113.094 1.00 48.05 ? 331 GLY B O 1 +ATOM 8618 N N . LYS C 1 270 ? -42.091 -18.541 -115.342 1.00 52.91 ? 332 LYS B N 1 +ATOM 8619 C CA . LYS C 1 270 ? -42.279 -19.980 -115.525 1.00 51.18 ? 332 LYS B CA 1 +ATOM 8620 C C . LYS C 1 270 ? -41.267 -20.502 -116.541 1.00 49.80 ? 332 LYS B C 1 +ATOM 8621 O O . LYS C 1 270 ? -41.619 -20.812 -117.685 1.00 49.15 ? 332 LYS B O 1 +ATOM 8622 C CB . LYS C 1 270 ? -43.711 -20.298 -115.964 1.00 54.58 ? 332 LYS B CB 1 +ATOM 8623 C CG . LYS C 1 270 ? -44.575 -20.946 -114.880 1.00 72.08 ? 332 LYS B CG 1 +ATOM 8624 C CD . LYS C 1 270 ? -44.948 -19.937 -113.787 1.00 84.09 ? 332 LYS B CD 1 +ATOM 8625 C CE . LYS C 1 270 ? -45.957 -20.499 -112.782 1.00 80.87 ? 332 LYS B CE 1 +ATOM 8626 N NZ . LYS C 1 270 ? -45.422 -21.648 -111.993 1.00 71.78 ? 332 LYS B NZ 1 +ATOM 8627 N N . PRO C 1 271 ? -39.981 -20.591 -116.160 1.00 48.34 ? 333 PRO B N 1 +ATOM 8628 C CA . PRO C 1 271 ? -39.400 -20.104 -114.909 1.00 40.66 ? 333 PRO B CA 1 +ATOM 8629 C C . PRO C 1 271 ? -38.852 -18.695 -115.072 1.00 43.13 ? 333 PRO B C 1 +ATOM 8630 O O . PRO C 1 271 ? -38.675 -17.993 -114.085 1.00 46.82 ? 333 PRO B O 1 +ATOM 8631 C CB . PRO C 1 271 ? -38.268 -21.092 -114.634 1.00 38.00 ? 333 PRO B CB 1 +ATOM 8632 C CG . PRO C 1 271 ? -37.914 -21.670 -115.975 1.00 47.86 ? 333 PRO B CG 1 +ATOM 8633 C CD . PRO C 1 271 ? -38.967 -21.263 -116.987 1.00 53.02 ? 333 PRO B CD 1 +ATOM 8634 N N . HIS C 1 272 ? -38.555 -18.296 -116.308 1.00 44.29 ? 334 HIS B N 1 +ATOM 8635 C CA . HIS C 1 272 ? -38.072 -16.953 -116.587 1.00 44.46 ? 334 HIS B CA 1 +ATOM 8636 C C . HIS C 1 272 ? -39.084 -16.066 -117.298 1.00 43.81 ? 334 HIS B C 1 +ATOM 8637 O O . HIS C 1 272 ? -38.966 -14.840 -117.215 1.00 41.99 ? 334 HIS B O 1 +ATOM 8638 C CB . HIS C 1 272 ? -36.787 -17.016 -117.425 1.00 48.97 ? 334 HIS B CB 1 +ATOM 8639 C CG . HIS C 1 272 ? -35.674 -17.777 -116.772 1.00 46.82 ? 334 HIS B CG 1 +ATOM 8640 N ND1 . HIS C 1 272 ? -34.708 -17.174 -115.993 1.00 47.53 ? 334 HIS B ND1 1 +ATOM 8641 C CD2 . HIS C 1 272 ? -35.378 -19.099 -116.781 1.00 47.76 ? 334 HIS B CD2 1 +ATOM 8642 C CE1 . HIS C 1 272 ? -33.862 -18.091 -115.557 1.00 54.65 ? 334 HIS B CE1 1 +ATOM 8643 N NE2 . HIS C 1 272 ? -34.247 -19.267 -116.019 1.00 58.81 ? 334 HIS B NE2 1 +ATOM 8644 N N . LEU C 1 273 ? -40.053 -16.645 -118.007 1.00 45.76 ? 335 LEU B N 1 +ATOM 8645 C CA . LEU C 1 273 ? -40.974 -15.869 -118.829 1.00 43.32 ? 335 LEU B CA 1 +ATOM 8646 C C . LEU C 1 273 ? -42.101 -15.293 -117.984 1.00 42.99 ? 335 LEU B C 1 +ATOM 8647 O O . LEU C 1 273 ? -42.793 -16.026 -117.271 1.00 45.61 ? 335 LEU B O 1 +ATOM 8648 C CB . LEU C 1 273 ? -41.561 -16.725 -119.950 1.00 43.25 ? 335 LEU B CB 1 +ATOM 8649 C CG . LEU C 1 273 ? -40.617 -17.113 -121.085 1.00 43.47 ? 335 LEU B CG 1 +ATOM 8650 C CD1 . LEU C 1 273 ? -39.752 -15.920 -121.452 1.00 38.00 ? 335 LEU B CD1 1 +ATOM 8651 C CD2 . LEU C 1 273 ? -39.774 -18.334 -120.719 1.00 56.67 ? 335 LEU B CD2 1 +ATOM 8652 N N . LEU C 1 274 ? -42.293 -13.981 -118.083 1.00 41.54 ? 336 LEU B N 1 +ATOM 8653 C CA . LEU C 1 274 ? -43.354 -13.280 -117.378 1.00 38.05 ? 336 LEU B CA 1 +ATOM 8654 C C . LEU C 1 274 ? -43.913 -12.193 -118.280 1.00 38.92 ? 336 LEU B C 1 +ATOM 8655 O O . LEU C 1 274 ? -43.152 -11.459 -118.919 1.00 41.00 ? 336 LEU B O 1 +ATOM 8656 C CB . LEU C 1 274 ? -42.832 -12.661 -116.082 1.00 40.42 ? 336 LEU B CB 1 +ATOM 8657 C CG . LEU C 1 274 ? -43.761 -11.650 -115.428 1.00 38.00 ? 336 LEU B CG 1 +ATOM 8658 C CD1 . LEU C 1 274 ? -44.946 -12.378 -114.826 1.00 42.52 ? 336 LEU B CD1 1 +ATOM 8659 C CD2 . LEU C 1 274 ? -43.006 -10.851 -114.390 1.00 38.00 ? 336 LEU B CD2 1 +ATOM 8660 N N . GLU C 1 275 ? -45.238 -12.086 -118.331 1.00 39.38 ? 337 GLU B N 1 +ATOM 8661 C CA . GLU C 1 275 ? -45.887 -11.102 -119.187 1.00 42.12 ? 337 GLU B CA 1 +ATOM 8662 C C . GLU C 1 275 ? -46.285 -9.863 -118.395 1.00 38.00 ? 337 GLU B C 1 +ATOM 8663 O O . GLU C 1 275 ? -46.696 -9.955 -117.236 1.00 38.00 ? 337 GLU B O 1 +ATOM 8664 C CB . GLU C 1 275 ? -47.107 -11.702 -119.893 1.00 41.79 ? 337 GLU B CB 1 +ATOM 8665 C CG . GLU C 1 275 ? -48.222 -12.177 -118.989 1.00 43.98 ? 337 GLU B CG 1 +ATOM 8666 C CD . GLU C 1 275 ? -49.436 -12.613 -119.786 1.00 41.04 ? 337 GLU B CD 1 +ATOM 8667 O OE1 . GLU C 1 275 ? -49.322 -13.591 -120.553 1.00 38.00 ? 337 GLU B OE1 1 +ATOM 8668 O OE2 . GLU C 1 275 ? -50.503 -11.976 -119.651 1.00 40.48 ? 337 GLU B OE2 1 +ATOM 8669 N N . GLY C 1 276 ? -46.175 -8.704 -119.043 1.00 38.00 ? 338 GLY B N 1 +ATOM 8670 C CA . GLY C 1 276 ? -46.473 -7.424 -118.439 1.00 38.00 ? 338 GLY B CA 1 +ATOM 8671 C C . GLY C 1 276 ? -46.927 -6.438 -119.492 1.00 38.00 ? 338 GLY B C 1 +ATOM 8672 O O . GLY C 1 276 ? -47.091 -6.785 -120.662 1.00 38.00 ? 338 GLY B O 1 +ATOM 8673 N N . SER C 1 277 ? -47.139 -5.197 -119.070 1.00 38.00 ? 339 SER B N 1 +ATOM 8674 C CA . SER C 1 277 ? -47.628 -4.150 -119.958 1.00 38.00 ? 339 SER B CA 1 +ATOM 8675 C C . SER C 1 277 ? -46.675 -2.968 -119.921 1.00 38.00 ? 339 SER B C 1 +ATOM 8676 O O . SER C 1 277 ? -46.481 -2.361 -118.863 1.00 39.60 ? 339 SER B O 1 +ATOM 8677 C CB . SER C 1 277 ? -49.023 -3.690 -119.546 1.00 38.66 ? 339 SER B CB 1 +ATOM 8678 O OG . SER C 1 277 ? -48.955 -2.954 -118.339 1.00 38.00 ? 339 SER B OG 1 +ATOM 8679 N N . LEU C 1 278 ? -46.121 -2.612 -121.074 1.00 38.00 ? 340 LEU B N 1 +ATOM 8680 C CA . LEU C 1 278 ? -45.219 -1.472 -121.180 1.00 38.00 ? 340 LEU B CA 1 +ATOM 8681 C C . LEU C 1 278 ? -45.991 -0.256 -121.674 1.00 39.79 ? 340 LEU B C 1 +ATOM 8682 O O . LEU C 1 278 ? -46.586 -0.291 -122.756 1.00 41.85 ? 340 LEU B O 1 +ATOM 8683 C CB . LEU C 1 278 ? -44.055 -1.780 -122.118 1.00 38.00 ? 340 LEU B CB 1 +ATOM 8684 C CG . LEU C 1 278 ? -43.240 -3.008 -121.735 1.00 38.00 ? 340 LEU B CG 1 +ATOM 8685 C CD1 . LEU C 1 278 ? -43.515 -4.128 -122.707 1.00 38.00 ? 340 LEU B CD1 1 +ATOM 8686 C CD2 . LEU C 1 278 ? -41.770 -2.673 -121.705 1.00 41.51 ? 340 LEU B CD2 1 +ATOM 8687 N N . SER C 1 279 ? -45.961 0.818 -120.894 1.00 40.29 ? 341 SER B N 1 +ATOM 8688 C CA . SER C 1 279 ? -46.642 2.063 -121.224 1.00 38.00 ? 341 SER B CA 1 +ATOM 8689 C C . SER C 1 279 ? -45.597 3.083 -121.659 1.00 38.00 ? 341 SER B C 1 +ATOM 8690 O O . SER C 1 279 ? -44.642 3.345 -120.923 1.00 38.00 ? 341 SER B O 1 +ATOM 8691 C CB . SER C 1 279 ? -47.451 2.566 -120.026 1.00 38.00 ? 341 SER B CB 1 +ATOM 8692 O OG . SER C 1 279 ? -48.251 3.690 -120.353 1.00 40.71 ? 341 SER B OG 1 +ATOM 8693 N N . ALA C 1 280 ? -45.766 3.630 -122.863 1.00 38.21 ? 342 ALA B N 1 +ATOM 8694 C CA . ALA C 1 280 ? -44.771 4.535 -123.426 1.00 38.00 ? 342 ALA B CA 1 +ATOM 8695 C C . ALA C 1 280 ? -44.530 5.720 -122.508 1.00 38.00 ? 342 ALA B C 1 +ATOM 8696 O O . ALA C 1 280 ? -45.450 6.236 -121.874 1.00 38.00 ? 342 ALA B O 1 +ATOM 8697 C CB . ALA C 1 280 ? -45.214 5.031 -124.799 1.00 38.00 ? 342 ALA B CB 1 +ATOM 8698 N N . PHE C 1 281 ? -43.281 6.157 -122.451 1.00 38.00 ? 343 PHE B N 1 +ATOM 8699 C CA . PHE C 1 281 ? -42.895 7.224 -121.546 1.00 40.23 ? 343 PHE B CA 1 +ATOM 8700 C C . PHE C 1 281 ? -43.276 8.576 -122.122 1.00 43.63 ? 343 PHE B C 1 +ATOM 8701 O O . PHE C 1 281 ? -43.088 8.832 -123.313 1.00 50.58 ? 343 PHE B O 1 +ATOM 8702 C CB . PHE C 1 281 ? -41.391 7.181 -121.295 1.00 43.46 ? 343 PHE B CB 1 +ATOM 8703 C CG . PHE C 1 281 ? -41.027 6.977 -119.861 1.00 46.02 ? 343 PHE B CG 1 +ATOM 8704 C CD1 . PHE C 1 281 ? -41.383 5.813 -119.208 1.00 44.58 ? 343 PHE B CD1 1 +ATOM 8705 C CD2 . PHE C 1 281 ? -40.321 7.944 -119.168 1.00 46.93 ? 343 PHE B CD2 1 +ATOM 8706 C CE1 . PHE C 1 281 ? -41.051 5.619 -117.888 1.00 48.64 ? 343 PHE B CE1 1 +ATOM 8707 C CE2 . PHE C 1 281 ? -39.982 7.756 -117.852 1.00 49.59 ? 343 PHE B CE2 1 +ATOM 8708 C CZ . PHE C 1 281 ? -40.348 6.592 -117.209 1.00 51.91 ? 343 PHE B CZ 1 +ATOM 8709 N N . LEU C 1 282 ? -43.805 9.446 -121.268 1.00 44.43 ? 344 LEU B N 1 +ATOM 8710 C CA . LEU C 1 282 ? -44.053 10.814 -121.672 1.00 43.03 ? 344 LEU B CA 1 +ATOM 8711 C C . LEU C 1 282 ? -42.728 11.569 -121.783 1.00 41.31 ? 344 LEU B C 1 +ATOM 8712 O O . LEU C 1 282 ? -41.696 11.102 -121.295 1.00 39.12 ? 344 LEU B O 1 +ATOM 8713 C CB . LEU C 1 282 ? -44.995 11.490 -120.678 1.00 44.35 ? 344 LEU B CB 1 +ATOM 8714 C CG . LEU C 1 282 ? -46.404 10.900 -120.556 1.00 38.00 ? 344 LEU B CG 1 +ATOM 8715 C CD1 . LEU C 1 282 ? -47.241 11.719 -119.592 1.00 38.00 ? 344 LEU B CD1 1 +ATOM 8716 C CD2 . LEU C 1 282 ? -47.083 10.816 -121.908 1.00 38.00 ? 344 LEU B CD2 1 +ATOM 8717 N N . PRO C 1 283 ? -42.721 12.717 -122.464 1.00 45.68 ? 345 PRO B N 1 +ATOM 8718 C CA . PRO C 1 283 ? -41.493 13.518 -122.548 1.00 46.57 ? 345 PRO B CA 1 +ATOM 8719 C C . PRO C 1 283 ? -41.003 13.957 -121.174 1.00 52.94 ? 345 PRO B C 1 +ATOM 8720 O O . PRO C 1 283 ? -41.768 14.056 -120.210 1.00 53.37 ? 345 PRO B O 1 +ATOM 8721 C CB . PRO C 1 283 ? -41.912 14.722 -123.399 1.00 48.09 ? 345 PRO B CB 1 +ATOM 8722 C CG . PRO C 1 283 ? -43.048 14.220 -124.220 1.00 45.97 ? 345 PRO B CG 1 +ATOM 8723 C CD . PRO C 1 283 ? -43.783 13.251 -123.336 1.00 47.65 ? 345 PRO B CD 1 +ATOM 8724 N N . SER C 1 284 ? -39.703 14.246 -121.105 1.00 53.99 ? 346 SER B N 1 +ATOM 8725 C CA . SER C 1 284 ? -39.067 14.591 -119.839 1.00 55.65 ? 346 SER B CA 1 +ATOM 8726 C C . SER C 1 284 ? -39.682 15.841 -119.235 1.00 49.52 ? 346 SER B C 1 +ATOM 8727 O O . SER C 1 284 ? -40.005 16.798 -119.943 1.00 51.45 ? 346 SER B O 1 +ATOM 8728 C CB . SER C 1 284 ? -37.567 14.809 -120.036 1.00 55.51 ? 346 SER B CB 1 +ATOM 8729 O OG . SER C 1 284 ? -36.933 13.624 -120.473 1.00 66.61 ? 346 SER B OG 1 +ATOM 8730 N N . LEU C 1 285 ? -39.820 15.840 -117.907 1.00 50.61 ? 347 LEU B N 1 +ATOM 8731 C CA . LEU C 1 285 ? -40.400 16.991 -117.228 1.00 56.54 ? 347 LEU B CA 1 +ATOM 8732 C C . LEU C 1 285 ? -39.543 18.239 -117.344 1.00 58.94 ? 347 LEU B C 1 +ATOM 8733 O O . LEU C 1 285 ? -40.025 19.332 -117.026 1.00 55.75 ? 347 LEU B O 1 +ATOM 8734 C CB . LEU C 1 285 ? -40.632 16.684 -115.752 1.00 51.58 ? 347 LEU B CB 1 +ATOM 8735 C CG . LEU C 1 285 ? -41.736 15.669 -115.502 1.00 52.29 ? 347 LEU B CG 1 +ATOM 8736 C CD1 . LEU C 1 285 ? -41.158 14.460 -114.794 1.00 51.01 ? 347 LEU B CD1 1 +ATOM 8737 C CD2 . LEU C 1 285 ? -42.866 16.314 -114.716 1.00 49.91 ? 347 LEU B CD2 1 +ATOM 8738 N N . ASN C 1 286 ? -38.295 18.107 -117.785 1.00 62.44 ? 348 ASN B N 1 +ATOM 8739 C CA . ASN C 1 286 ? -37.476 19.273 -118.073 1.00 56.39 ? 348 ASN B CA 1 +ATOM 8740 C C . ASN C 1 286 ? -37.870 19.929 -119.383 1.00 56.87 ? 348 ASN B C 1 +ATOM 8741 O O . ASN C 1 286 ? -37.590 21.116 -119.577 1.00 65.77 ? 348 ASN B O 1 +ATOM 8742 C CB . ASN C 1 286 ? -36.002 18.869 -118.108 1.00 57.46 ? 348 ASN B CB 1 +ATOM 8743 C CG . ASN C 1 286 ? -35.505 18.350 -116.769 1.00 64.25 ? 348 ASN B CG 1 +ATOM 8744 O OD1 . ASN C 1 286 ? -36.006 18.737 -115.709 1.00 57.46 ? 348 ASN B OD1 1 +ATOM 8745 N ND2 . ASN C 1 286 ? -34.544 17.433 -116.814 1.00 63.02 ? 348 ASN B ND2 1 +ATOM 8746 N N . LEU C 1 287 ? -38.543 19.195 -120.267 1.00 55.84 ? 349 LEU B N 1 +ATOM 8747 C CA . LEU C 1 287 ? -38.999 19.732 -121.542 1.00 51.10 ? 349 LEU B CA 1 +ATOM 8748 C C . LEU C 1 287 ? -40.484 20.045 -121.560 1.00 53.85 ? 349 LEU B C 1 +ATOM 8749 O O . LEU C 1 287 ? -40.891 21.022 -122.195 1.00 61.43 ? 349 LEU B O 1 +ATOM 8750 C CB . LEU C 1 287 ? -38.694 18.741 -122.671 1.00 47.56 ? 349 LEU B CB 1 +ATOM 8751 C CG . LEU C 1 287 ? -37.227 18.382 -122.888 1.00 46.64 ? 349 LEU B CG 1 +ATOM 8752 C CD1 . LEU C 1 287 ? -37.082 17.366 -124.006 1.00 40.82 ? 349 LEU B CD1 1 +ATOM 8753 C CD2 . LEU C 1 287 ? -36.437 19.643 -123.188 1.00 50.89 ? 349 LEU B CD2 1 +ATOM 8754 N N . ALA C 1 288 ? -41.295 19.264 -120.850 1.00 54.29 ? 350 ALA B N 1 +ATOM 8755 C CA . ALA C 1 288 ? -42.743 19.457 -120.827 1.00 54.25 ? 350 ALA B CA 1 +ATOM 8756 C C . ALA C 1 288 ? -43.218 19.247 -119.401 1.00 51.25 ? 350 ALA B C 1 +ATOM 8757 O O . ALA C 1 288 ? -43.632 18.143 -119.022 1.00 50.77 ? 350 ALA B O 1 +ATOM 8758 C CB . ALA C 1 288 ? -43.454 18.506 -121.790 1.00 53.50 ? 350 ALA B CB 1 +ATOM 8759 N N . PRO C 1 289 ? -43.182 20.297 -118.580 1.00 45.47 ? 351 PRO B N 1 +ATOM 8760 C CA . PRO C 1 289 ? -43.582 20.149 -117.179 1.00 51.81 ? 351 PRO B CA 1 +ATOM 8761 C C . PRO C 1 289 ? -45.040 19.736 -117.068 1.00 53.32 ? 351 PRO B C 1 +ATOM 8762 O O . PRO C 1 289 ? -45.875 20.080 -117.907 1.00 53.03 ? 351 PRO B O 1 +ATOM 8763 C CB . PRO C 1 289 ? -43.348 21.546 -116.591 1.00 54.02 ? 351 PRO B CB 1 +ATOM 8764 C CG . PRO C 1 289 ? -42.414 22.225 -117.560 1.00 46.50 ? 351 PRO B CG 1 +ATOM 8765 C CD . PRO C 1 289 ? -42.751 21.667 -118.897 1.00 38.34 ? 351 PRO B CD 1 +ATOM 8766 N N . ARG C 1 290 ? -45.341 18.985 -116.017 1.00 49.62 ? 352 ARG B N 1 +ATOM 8767 C CA . ARG C 1 290 ? -46.688 18.494 -115.796 1.00 50.32 ? 352 ARG B CA 1 +ATOM 8768 C C . ARG C 1 290 ? -47.176 18.960 -114.435 1.00 51.55 ? 352 ARG B C 1 +ATOM 8769 O O . ARG C 1 290 ? -46.395 19.397 -113.585 1.00 49.93 ? 352 ARG B O 1 +ATOM 8770 C CB . ARG C 1 290 ? -46.750 16.969 -115.900 1.00 50.44 ? 352 ARG B CB 1 +ATOM 8771 C CG . ARG C 1 290 ? -46.308 16.456 -117.253 1.00 48.87 ? 352 ARG B CG 1 +ATOM 8772 C CD . ARG C 1 290 ? -46.801 15.050 -117.507 1.00 50.56 ? 352 ARG B CD 1 +ATOM 8773 N NE . ARG C 1 290 ? -46.124 14.055 -116.685 1.00 48.61 ? 352 ARG B NE 1 +ATOM 8774 C CZ . ARG C 1 290 ? -44.941 13.531 -116.979 1.00 50.89 ? 352 ARG B CZ 1 +ATOM 8775 N NH1 . ARG C 1 290 ? -44.292 13.918 -118.069 1.00 52.03 ? 352 ARG B NH1 1 +ATOM 8776 N NH2 . ARG C 1 290 ? -44.405 12.621 -116.180 1.00 56.86 ? 352 ARG B NH2 1 +ATOM 8777 N N . LEU C 1 291 ? -48.489 18.877 -114.245 1.00 49.30 ? 353 LEU B N 1 +ATOM 8778 C CA . LEU C 1 291 ? -49.154 19.434 -113.070 1.00 47.53 ? 353 LEU B CA 1 +ATOM 8779 C C . LEU C 1 291 ? -50.136 18.386 -112.558 1.00 49.95 ? 353 LEU B C 1 +ATOM 8780 O O . LEU C 1 291 ? -51.213 18.208 -113.133 1.00 56.72 ? 353 LEU B O 1 +ATOM 8781 C CB . LEU C 1 291 ? -49.861 20.741 -113.413 1.00 49.72 ? 353 LEU B CB 1 +ATOM 8782 C CG . LEU C 1 291 ? -49.903 21.863 -112.373 1.00 57.24 ? 353 LEU B CG 1 +ATOM 8783 C CD1 . LEU C 1 291 ? -50.530 23.115 -112.977 1.00 57.09 ? 353 LEU B CD1 1 +ATOM 8784 C CD2 . LEU C 1 291 ? -50.639 21.442 -111.100 1.00 59.99 ? 353 LEU B CD2 1 +ATOM 8785 N N . SER C 1 292 ? -49.759 17.675 -111.502 1.00 46.09 ? 354 SER B N 1 +ATOM 8786 C CA . SER C 1 292 ? -50.673 16.725 -110.879 1.00 44.86 ? 354 SER B CA 1 +ATOM 8787 C C . SER C 1 292 ? -51.778 17.504 -110.176 1.00 45.69 ? 354 SER B C 1 +ATOM 8788 O O . SER C 1 292 ? -51.516 18.225 -109.208 1.00 43.44 ? 354 SER B O 1 +ATOM 8789 C CB . SER C 1 292 ? -49.921 15.823 -109.905 1.00 50.42 ? 354 SER B CB 1 +ATOM 8790 O OG . SER C 1 292 ? -50.659 14.646 -109.619 1.00 47.21 ? 354 SER B OG 1 +ATOM 8791 N N . VAL C 1 293 ? -52.995 17.410 -110.690 1.00 46.53 ? 355 VAL B N 1 +ATOM 8792 C CA . VAL C 1 293 ? -54.154 18.117 -110.147 1.00 46.98 ? 355 VAL B CA 1 +ATOM 8793 C C . VAL C 1 293 ? -55.033 17.109 -109.421 1.00 45.59 ? 355 VAL B C 1 +ATOM 8794 O O . VAL C 1 293 ? -55.352 16.060 -109.992 1.00 42.14 ? 355 VAL B O 1 +ATOM 8795 C CB . VAL C 1 293 ? -54.960 18.840 -111.245 1.00 45.23 ? 355 VAL B CB 1 +ATOM 8796 C CG1 . VAL C 1 293 ? -56.251 19.389 -110.668 1.00 46.45 ? 355 VAL B CG1 1 +ATOM 8797 C CG2 . VAL C 1 293 ? -54.142 19.964 -111.853 1.00 49.33 ? 355 VAL B CG2 1 +ATOM 8798 N N . PRO C 1 294 ? -55.453 17.386 -108.186 1.00 51.54 ? 356 PRO B N 1 +ATOM 8799 C CA . PRO C 1 294 ? -56.373 16.473 -107.502 1.00 49.22 ? 356 PRO B CA 1 +ATOM 8800 C C . PRO C 1 294 ? -57.756 16.498 -108.135 1.00 49.29 ? 356 PRO B C 1 +ATOM 8801 O O . PRO C 1 294 ? -58.264 17.549 -108.536 1.00 49.33 ? 356 PRO B O 1 +ATOM 8802 C CB . PRO C 1 294 ? -56.404 17.008 -106.066 1.00 46.06 ? 356 PRO B CB 1 +ATOM 8803 C CG . PRO C 1 294 ? -56.040 18.446 -106.193 1.00 48.34 ? 356 PRO B CG 1 +ATOM 8804 C CD . PRO C 1 294 ? -55.061 18.521 -107.332 1.00 50.14 ? 356 PRO B CD 1 +ATOM 8805 N N . ASN C 1 295 ? -58.345 15.314 -108.247 1.00 46.30 ? 357 ASN B N 1 +ATOM 8806 C CA . ASN C 1 295 ? -59.704 15.191 -108.742 1.00 46.39 ? 357 ASN B CA 1 +ATOM 8807 C C . ASN C 1 295 ? -60.656 15.955 -107.821 1.00 48.18 ? 357 ASN B C 1 +ATOM 8808 O O . ASN C 1 295 ? -60.416 16.051 -106.617 1.00 54.12 ? 357 ASN B O 1 +ATOM 8809 C CB . ASN C 1 295 ? -60.089 13.712 -108.791 1.00 44.92 ? 357 ASN B CB 1 +ATOM 8810 C CG . ASN C 1 295 ? -61.337 13.452 -109.592 1.00 42.53 ? 357 ASN B CG 1 +ATOM 8811 O OD1 . ASN C 1 295 ? -62.428 13.799 -109.170 1.00 45.56 ? 357 ASN B OD1 1 +ATOM 8812 N ND2 . ASN C 1 295 ? -61.188 12.800 -110.736 1.00 39.95 ? 357 ASN B ND2 1 +ATOM 8813 N N . PRO C 1 296 ? -61.729 16.542 -108.358 1.00 45.56 ? 358 PRO B N 1 +ATOM 8814 C CA . PRO C 1 296 ? -62.782 17.068 -107.476 1.00 44.85 ? 358 PRO B CA 1 +ATOM 8815 C C . PRO C 1 296 ? -63.652 15.982 -106.873 1.00 48.24 ? 358 PRO B C 1 +ATOM 8816 O O . PRO C 1 296 ? -64.420 16.271 -105.947 1.00 57.11 ? 358 PRO B O 1 +ATOM 8817 C CB . PRO C 1 296 ? -63.603 17.980 -108.400 1.00 45.31 ? 358 PRO B CB 1 +ATOM 8818 C CG . PRO C 1 296 ? -62.713 18.267 -109.544 1.00 53.23 ? 358 PRO B CG 1 +ATOM 8819 C CD . PRO C 1 296 ? -61.876 17.038 -109.733 1.00 49.79 ? 358 PRO B CD 1 +ATOM 8820 N N . TRP C 1 297 ? -63.579 14.756 -107.383 1.00 42.50 ? 359 TRP B N 1 +ATOM 8821 C CA . TRP C 1 297 ? -64.367 13.654 -106.849 1.00 44.81 ? 359 TRP B CA 1 +ATOM 8822 C C . TRP C 1 297 ? -63.448 12.581 -106.280 1.00 42.18 ? 359 TRP B C 1 +ATOM 8823 O O . TRP C 1 297 ? -63.568 11.407 -106.641 1.00 44.66 ? 359 TRP B O 1 +ATOM 8824 C CB . TRP C 1 297 ? -65.269 13.056 -107.932 1.00 49.18 ? 359 TRP B CB 1 +ATOM 8825 C CG . TRP C 1 297 ? -66.490 13.871 -108.292 1.00 48.88 ? 359 TRP B CG 1 +ATOM 8826 C CD1 . TRP C 1 297 ? -67.758 13.710 -107.812 1.00 47.94 ? 359 TRP B CD1 1 +ATOM 8827 C CD2 . TRP C 1 297 ? -66.554 14.955 -109.232 1.00 50.81 ? 359 TRP B CD2 1 +ATOM 8828 N NE1 . TRP C 1 297 ? -68.604 14.629 -108.387 1.00 50.74 ? 359 TRP B NE1 1 +ATOM 8829 C CE2 . TRP C 1 297 ? -67.889 15.404 -109.263 1.00 53.60 ? 359 TRP B CE2 1 +ATOM 8830 C CE3 . TRP C 1 297 ? -65.611 15.589 -110.048 1.00 45.24 ? 359 TRP B CE3 1 +ATOM 8831 C CZ2 . TRP C 1 297 ? -68.301 16.459 -110.076 1.00 52.89 ? 359 TRP B CZ2 1 +ATOM 8832 C CZ3 . TRP C 1 297 ? -66.022 16.633 -110.850 1.00 40.21 ? 359 TRP B CZ3 1 +ATOM 8833 C CH2 . TRP C 1 297 ? -67.354 17.059 -110.859 1.00 46.67 ? 359 TRP B CH2 1 +ATOM 8834 N N . ILE C 1 298 ? -62.505 12.969 -105.418 1.00 44.32 ? 360 ILE B N 1 +ATOM 8835 C CA . ILE C 1 298 ? -61.652 11.966 -104.790 1.00 47.43 ? 360 ILE B CA 1 +ATOM 8836 C C . ILE C 1 298 ? -62.488 11.073 -103.881 1.00 44.15 ? 360 ILE B C 1 +ATOM 8837 O O . ILE C 1 298 ? -63.594 11.420 -103.456 1.00 45.79 ? 360 ILE B O 1 +ATOM 8838 C CB . ILE C 1 298 ? -60.499 12.605 -103.999 1.00 44.62 ? 360 ILE B CB 1 +ATOM 8839 C CG1 . ILE C 1 298 ? -60.258 14.050 -104.439 1.00 49.64 ? 360 ILE B CG1 1 +ATOM 8840 C CG2 . ILE C 1 298 ? -59.243 11.756 -104.129 1.00 38.00 ? 360 ILE B CG2 1 +ATOM 8841 C CD1 . ILE C 1 298 ? -60.980 15.111 -103.590 1.00 53.04 ? 360 ILE B CD1 1 +ATOM 8842 N N . ARG C 1 299 ? -61.946 9.901 -103.585 1.00 44.68 ? 361 ARG B N 1 +ATOM 8843 C CA . ARG C 1 299 ? -62.532 9.037 -102.577 1.00 51.49 ? 361 ARG B CA 1 +ATOM 8844 C C . ARG C 1 299 ? -61.907 9.319 -101.214 1.00 59.07 ? 361 ARG B C 1 +ATOM 8845 O O . ARG C 1 299 ? -60.885 9.997 -101.096 1.00 65.21 ? 361 ARG B O 1 +ATOM 8846 C CB . ARG C 1 299 ? -62.358 7.576 -102.959 1.00 48.22 ? 361 ARG B CB 1 +ATOM 8847 C CG . ARG C 1 299 ? -63.647 6.916 -103.357 1.00 47.73 ? 361 ARG B CG 1 +ATOM 8848 C CD . ARG C 1 299 ? -63.778 6.831 -104.854 1.00 44.56 ? 361 ARG B CD 1 +ATOM 8849 N NE . ARG C 1 299 ? -64.904 5.983 -105.218 1.00 45.88 ? 361 ARG B NE 1 +ATOM 8850 C CZ . ARG C 1 299 ? -65.302 5.758 -106.463 1.00 50.76 ? 361 ARG B CZ 1 +ATOM 8851 N NH1 . ARG C 1 299 ? -64.663 6.323 -107.480 1.00 57.58 ? 361 ARG B NH1 1 +ATOM 8852 N NH2 . ARG C 1 299 ? -66.338 4.964 -106.690 1.00 50.37 ? 361 ARG B NH2 1 +ATOM 8853 N N . SER C 1 300 ? -62.550 8.800 -100.165 1.00 51.06 ? 362 SER B N 1 +ATOM 8854 C CA . SER C 1 300 ? -62.020 9.007 -98.823 1.00 53.01 ? 362 SER B CA 1 +ATOM 8855 C C . SER C 1 300 ? -60.698 8.279 -98.624 1.00 48.55 ? 362 SER B C 1 +ATOM 8856 O O . SER C 1 300 ? -59.825 8.771 -97.900 1.00 45.40 ? 362 SER B O 1 +ATOM 8857 C CB . SER C 1 300 ? -63.042 8.558 -97.777 1.00 59.89 ? 362 SER B CB 1 +ATOM 8858 O OG . SER C 1 300 ? -63.361 7.183 -97.915 1.00 64.10 ? 362 SER B OG 1 +ATOM 8859 N N . TYR C 1 301 ? -60.517 7.141 -99.290 1.00 49.59 ? 363 TYR B N 1 +ATOM 8860 C CA . TYR C 1 301 ? -59.358 6.277 -99.073 1.00 49.82 ? 363 TYR B CA 1 +ATOM 8861 C C . TYR C 1 301 ? -59.251 5.883 -97.601 1.00 53.95 ? 363 TYR B C 1 +ATOM 8862 O O . TYR C 1 301 ? -58.188 5.971 -96.984 1.00 60.29 ? 363 TYR B O 1 +ATOM 8863 C CB . TYR C 1 301 ? -58.067 6.933 -99.569 1.00 51.86 ? 363 TYR B CB 1 +ATOM 8864 C CG . TYR C 1 301 ? -57.967 7.001 -101.076 1.00 54.48 ? 363 TYR B CG 1 +ATOM 8865 C CD1 . TYR C 1 301 ? -57.526 5.908 -101.819 1.00 50.66 ? 363 TYR B CD1 1 +ATOM 8866 C CD2 . TYR C 1 301 ? -58.323 8.154 -101.756 1.00 57.89 ? 363 TYR B CD2 1 +ATOM 8867 C CE1 . TYR C 1 301 ? -57.442 5.974 -103.200 1.00 51.72 ? 363 TYR B CE1 1 +ATOM 8868 C CE2 . TYR C 1 301 ? -58.245 8.228 -103.131 1.00 61.15 ? 363 TYR B CE2 1 +ATOM 8869 C CZ . TYR C 1 301 ? -57.806 7.142 -103.849 1.00 57.57 ? 363 TYR B CZ 1 +ATOM 8870 O OH . TYR C 1 301 ? -57.742 7.250 -105.219 1.00 54.19 ? 363 TYR B OH 1 +ATOM 8871 N N . THR C 1 302 ? -60.384 5.474 -97.030 1.00 54.05 ? 364 THR B N 1 +ATOM 8872 C CA . THR C 1 302 ? -60.440 4.970 -95.665 1.00 53.20 ? 364 THR B CA 1 +ATOM 8873 C C . THR C 1 302 ? -61.436 3.822 -95.605 1.00 53.18 ? 364 THR B C 1 +ATOM 8874 O O . THR C 1 302 ? -62.268 3.647 -96.499 1.00 56.20 ? 364 THR B O 1 +ATOM 8875 C CB . THR C 1 302 ? -60.841 6.049 -94.651 1.00 52.75 ? 364 THR B CB 1 +ATOM 8876 O OG1 . THR C 1 302 ? -60.508 7.343 -95.164 1.00 53.45 ? 364 THR B OG1 1 +ATOM 8877 C CG2 . THR C 1 302 ? -60.107 5.827 -93.328 1.00 56.30 ? 364 THR B CG2 1 +ATOM 8878 N N . LEU C 1 303 ? -61.357 3.048 -94.520 1.00 47.61 ? 365 LEU B N 1 +ATOM 8879 C CA . LEU C 1 303 ? -62.287 1.942 -94.315 1.00 53.46 ? 365 LEU B CA 1 +ATOM 8880 C C . LEU C 1 303 ? -63.721 2.411 -94.088 1.00 58.66 ? 365 LEU B C 1 +ATOM 8881 O O . LEU C 1 303 ? -64.649 1.598 -94.183 1.00 53.19 ? 365 LEU B O 1 +ATOM 8882 C CB . LEU C 1 303 ? -61.824 1.083 -93.134 1.00 54.79 ? 365 LEU B CB 1 +ATOM 8883 C CG . LEU C 1 303 ? -60.483 0.359 -93.290 1.00 48.74 ? 365 LEU B CG 1 +ATOM 8884 C CD1 . LEU C 1 303 ? -60.118 -0.438 -92.037 1.00 45.90 ? 365 LEU B CD1 1 +ATOM 8885 C CD2 . LEU C 1 303 ? -60.527 -0.547 -94.506 1.00 51.64 ? 365 LEU B CD2 1 +ATOM 8886 N N . ALA C 1 304 ? -63.923 3.698 -93.819 1.00 54.56 ? 366 ALA B N 1 +ATOM 8887 C CA . ALA C 1 304 ? -65.245 4.278 -93.653 1.00 45.35 ? 366 ALA B CA 1 +ATOM 8888 C C . ALA C 1 304 ? -65.162 5.740 -94.065 1.00 57.16 ? 366 ALA B C 1 +ATOM 8889 O O . ALA C 1 304 ? -64.112 6.223 -94.499 1.00 62.52 ? 366 ALA B O 1 +ATOM 8890 C CB . ALA C 1 304 ? -65.747 4.124 -92.216 1.00 46.41 ? 366 ALA B CB 1 +ATOM 8891 N N . GLY C 1 305 ? -66.287 6.441 -93.960 1.00 59.79 ? 367 GLY B N 1 +ATOM 8892 C CA . GLY C 1 305 ? -66.308 7.850 -94.299 1.00 63.49 ? 367 GLY B CA 1 +ATOM 8893 C C . GLY C 1 305 ? -66.471 8.098 -95.783 1.00 55.47 ? 367 GLY B C 1 +ATOM 8894 O O . GLY C 1 305 ? -65.812 7.456 -96.606 1.00 49.60 ? 367 GLY B O 1 +ATOM 8895 N N . LYS C 1 306 ? -67.345 9.037 -96.133 1.00 52.95 ? 368 LYS B N 1 +ATOM 8896 C CA . LYS C 1 306 ? -67.623 9.385 -97.516 1.00 48.30 ? 368 LYS B CA 1 +ATOM 8897 C C . LYS C 1 306 ? -67.275 10.846 -97.758 1.00 48.02 ? 368 LYS B C 1 +ATOM 8898 O O . LYS C 1 306 ? -67.290 11.665 -96.835 1.00 48.53 ? 368 LYS B O 1 +ATOM 8899 C CB . LYS C 1 306 ? -69.097 9.140 -97.876 1.00 44.46 ? 368 LYS B CB 1 +ATOM 8900 C CG . LYS C 1 306 ? -69.910 8.460 -96.790 1.00 54.03 ? 368 LYS B CG 1 +ATOM 8901 C CD . LYS C 1 306 ? -69.657 6.952 -96.723 1.00 57.46 ? 368 LYS B CD 1 +ATOM 8902 C CE . LYS C 1 306 ? -70.278 6.225 -97.905 1.00 62.84 ? 368 LYS B CE 1 +ATOM 8903 N NZ . LYS C 1 306 ? -70.191 4.747 -97.750 1.00 55.62 ? 368 LYS B NZ 1 +ATOM 8904 N N . GLU C 1 307 ? -66.950 11.163 -99.010 1.00 45.56 ? 369 GLU B N 1 +ATOM 8905 C CA . GLU C 1 307 ? -66.656 12.535 -99.380 1.00 43.09 ? 369 GLU B CA 1 +ATOM 8906 C C . GLU C 1 307 ? -67.953 13.307 -99.611 1.00 45.12 ? 369 GLU B C 1 +ATOM 8907 O O . GLU C 1 307 ? -69.050 12.745 -99.625 1.00 46.28 ? 369 GLU B O 1 +ATOM 8908 C CB . GLU C 1 307 ? -65.756 12.568 -100.610 1.00 45.46 ? 369 GLU B CB 1 +ATOM 8909 C CG . GLU C 1 307 ? -64.337 12.105 -100.332 1.00 47.32 ? 369 GLU B CG 1 +ATOM 8910 C CD . GLU C 1 307 ? -63.575 13.057 -99.432 1.00 54.66 ? 369 GLU B CD 1 +ATOM 8911 O OE1 . GLU C 1 307 ? -63.936 14.252 -99.387 1.00 62.84 ? 369 GLU B OE1 1 +ATOM 8912 O OE2 . GLU C 1 307 ? -62.619 12.610 -98.763 1.00 60.27 ? 369 GLU B OE2 1 +ATOM 8913 N N . GLU C 1 308 ? -67.816 14.616 -99.841 1.00 48.54 ? 370 GLU B N 1 +ATOM 8914 C CA . GLU C 1 308 ? -68.990 15.476 -99.953 1.00 51.20 ? 370 GLU B CA 1 +ATOM 8915 C C . GLU C 1 308 ? -69.846 15.097 -101.157 1.00 52.44 ? 370 GLU B C 1 +ATOM 8916 O O . GLU C 1 308 ? -71.078 15.054 -101.059 1.00 49.11 ? 370 GLU B O 1 +ATOM 8917 C CB . GLU C 1 308 ? -68.557 16.941 -100.031 1.00 52.64 ? 370 GLU B CB 1 +ATOM 8918 C CG . GLU C 1 308 ? -69.338 17.870 -99.105 1.00 60.98 ? 370 GLU B CG 1 +ATOM 8919 C CD . GLU C 1 308 ? -70.270 18.812 -99.854 1.00 62.85 ? 370 GLU B CD 1 +ATOM 8920 O OE1 . GLU C 1 308 ? -69.775 19.636 -100.655 1.00 55.81 ? 370 GLU B OE1 1 +ATOM 8921 O OE2 . GLU C 1 308 ? -71.500 18.723 -99.646 1.00 63.73 ? 370 GLU B OE2 1 +ATOM 8922 N N . TRP C 1 309 ? -69.210 14.813 -102.299 1.00 53.95 ? 371 TRP B N 1 +ATOM 8923 C CA . TRP C 1 309 ? -69.958 14.427 -103.494 1.00 55.56 ? 371 TRP B CA 1 +ATOM 8924 C C . TRP C 1 309 ? -70.700 13.114 -103.294 1.00 54.46 ? 371 TRP B C 1 +ATOM 8925 O O . TRP C 1 309 ? -71.716 12.860 -103.955 1.00 54.29 ? 371 TRP B O 1 +ATOM 8926 C CB . TRP C 1 309 ? -69.019 14.310 -104.694 1.00 49.93 ? 371 TRP B CB 1 +ATOM 8927 C CG . TRP C 1 309 ? -67.987 13.224 -104.567 1.00 48.77 ? 371 TRP B CG 1 +ATOM 8928 C CD1 . TRP C 1 309 ? -66.725 13.352 -104.070 1.00 48.90 ? 371 TRP B CD1 1 +ATOM 8929 C CD2 . TRP C 1 309 ? -68.129 11.845 -104.950 1.00 46.11 ? 371 TRP B CD2 1 +ATOM 8930 N NE1 . TRP C 1 309 ? -66.071 12.144 -104.120 1.00 48.47 ? 371 TRP B NE1 1 +ATOM 8931 C CE2 . TRP C 1 309 ? -66.912 11.203 -104.655 1.00 43.75 ? 371 TRP B CE2 1 +ATOM 8932 C CE3 . TRP C 1 309 ? -69.165 11.095 -105.513 1.00 47.95 ? 371 TRP B CE3 1 +ATOM 8933 C CZ2 . TRP C 1 309 ? -66.703 9.849 -104.904 1.00 41.89 ? 371 TRP B CZ2 1 +ATOM 8934 C CZ3 . TRP C 1 309 ? -68.954 9.750 -105.759 1.00 43.30 ? 371 TRP B CZ3 1 +ATOM 8935 C CH2 . TRP C 1 309 ? -67.735 9.142 -105.455 1.00 40.31 ? 371 TRP B CH2 1 +ATOM 8936 N N . GLU C 1 310 ? -70.206 12.262 -102.402 1.00 48.17 ? 372 GLU B N 1 +ATOM 8937 C CA . GLU C 1 310 ? -70.863 10.991 -102.164 1.00 45.40 ? 372 GLU B CA 1 +ATOM 8938 C C . GLU C 1 310 ? -72.212 11.148 -101.477 1.00 48.48 ? 372 GLU B C 1 +ATOM 8939 O O . GLU C 1 310 ? -73.027 10.223 -101.536 1.00 48.43 ? 372 GLU B O 1 +ATOM 8940 C CB . GLU C 1 310 ? -69.928 10.106 -101.338 1.00 43.46 ? 372 GLU B CB 1 +ATOM 8941 C CG . GLU C 1 310 ? -69.190 9.065 -102.151 1.00 42.40 ? 372 GLU B CG 1 +ATOM 8942 C CD . GLU C 1 310 ? -68.060 8.418 -101.384 1.00 38.00 ? 372 GLU B CD 1 +ATOM 8943 O OE1 . GLU C 1 310 ? -67.250 9.158 -100.789 1.00 38.00 ? 372 GLU B OE1 1 +ATOM 8944 O OE2 . GLU C 1 310 ? -67.993 7.171 -101.359 1.00 38.00 ? 372 GLU B OE2 1 +ATOM 8945 N N . VAL C 1 311 ? -72.495 12.314 -100.895 1.00 52.03 ? 373 VAL B N 1 +ATOM 8946 C CA . VAL C 1 311 ? -73.690 12.500 -100.076 1.00 55.68 ? 373 VAL B CA 1 +ATOM 8947 C C . VAL C 1 311 ? -74.575 13.612 -100.629 1.00 57.34 ? 373 VAL B C 1 +ATOM 8948 O O . VAL C 1 311 ? -75.804 13.563 -100.494 1.00 50.70 ? 373 VAL B O 1 +ATOM 8949 C CB . VAL C 1 311 ? -73.302 12.792 -98.615 1.00 50.25 ? 373 VAL B CB 1 +ATOM 8950 C CG1 . VAL C 1 311 ? -74.538 12.850 -97.730 1.00 52.58 ? 373 VAL B CG1 1 +ATOM 8951 C CG2 . VAL C 1 311 ? -72.331 11.734 -98.105 1.00 47.04 ? 373 VAL B CG2 1 +ATOM 8952 N N . ASN C 1 312 ? -73.962 14.616 -101.262 1.00 58.47 ? 374 ASN B N 1 +ATOM 8953 C CA . ASN C 1 312 ? -74.685 15.791 -101.730 1.00 56.92 ? 374 ASN B CA 1 +ATOM 8954 C C . ASN C 1 312 ? -74.955 15.694 -103.223 1.00 52.33 ? 374 ASN B C 1 +ATOM 8955 O O . ASN C 1 312 ? -74.027 15.894 -104.020 1.00 53.38 ? 374 ASN B O 1 +ATOM 8956 C CB . ASN C 1 312 ? -73.890 17.059 -101.416 1.00 50.39 ? 374 ASN B CB 1 +ATOM 8957 C CG . ASN C 1 312 ? -74.525 18.306 -101.996 1.00 53.90 ? 374 ASN B CG 1 +ATOM 8958 O OD1 . ASN C 1 312 ? -75.710 18.320 -102.332 1.00 54.78 ? 374 ASN B OD1 1 +ATOM 8959 N ND2 . ASN C 1 312 ? -73.741 19.370 -102.104 1.00 57.31 ? 374 ASN B ND2 1 +ATOM 8960 N N . PRO C 1 313 ? -76.200 15.449 -103.655 1.00 50.37 ? 375 PRO B N 1 +ATOM 8961 C CA . PRO C 1 313 ? -76.487 15.418 -105.099 1.00 55.97 ? 375 PRO B CA 1 +ATOM 8962 C C . PRO C 1 313 ? -76.290 16.755 -105.789 1.00 54.94 ? 375 PRO B C 1 +ATOM 8963 O O . PRO C 1 313 ? -76.232 16.788 -107.026 1.00 50.17 ? 375 PRO B O 1 +ATOM 8964 C CB . PRO C 1 313 ? -77.959 14.982 -105.161 1.00 51.08 ? 375 PRO B CB 1 +ATOM 8965 C CG . PRO C 1 313 ? -78.251 14.383 -103.834 1.00 48.62 ? 375 PRO B CG 1 +ATOM 8966 C CD . PRO C 1 313 ? -77.382 15.100 -102.854 1.00 52.36 ? 375 PRO B CD 1 +ATOM 8967 N N . LEU C 1 314 ? -76.190 17.851 -105.038 1.00 51.97 ? 376 LEU B N 1 +ATOM 8968 C CA . LEU C 1 314 ? -75.922 19.170 -105.598 1.00 58.06 ? 376 LEU B CA 1 +ATOM 8969 C C . LEU C 1 314 ? -74.449 19.543 -105.500 1.00 59.90 ? 376 LEU B C 1 +ATOM 8970 O O . LEU C 1 314 ? -74.113 20.731 -105.443 1.00 65.66 ? 376 LEU B O 1 +ATOM 8971 C CB . LEU C 1 314 ? -76.786 20.225 -104.909 1.00 59.91 ? 376 LEU B CB 1 +ATOM 8972 C CG . LEU C 1 314 ? -78.297 20.056 -105.067 1.00 64.05 ? 376 LEU B CG 1 +ATOM 8973 C CD1 . LEU C 1 314 ? -79.023 20.964 -104.101 1.00 69.04 ? 376 LEU B CD1 1 +ATOM 8974 C CD2 . LEU C 1 314 ? -78.727 20.355 -106.499 1.00 57.85 ? 376 LEU B CD2 1 +ATOM 8975 N N . TYR C 1 315 ? -73.561 18.546 -105.478 1.00 54.39 ? 377 TYR B N 1 +ATOM 8976 C CA . TYR C 1 315 ? -72.140 18.835 -105.316 1.00 52.95 ? 377 TYR B CA 1 +ATOM 8977 C C . TYR C 1 315 ? -71.599 19.646 -106.485 1.00 57.47 ? 377 TYR B C 1 +ATOM 8978 O O . TYR C 1 315 ? -70.795 20.564 -106.288 1.00 56.62 ? 377 TYR B O 1 +ATOM 8979 C CB . TYR C 1 315 ? -71.343 17.539 -105.150 1.00 51.57 ? 377 TYR B CB 1 +ATOM 8980 C CG . TYR C 1 315 ? -69.860 17.779 -104.964 1.00 56.16 ? 377 TYR B CG 1 +ATOM 8981 C CD1 . TYR C 1 315 ? -69.369 18.292 -103.771 1.00 62.29 ? 377 TYR B CD1 1 +ATOM 8982 C CD2 . TYR C 1 315 ? -68.950 17.482 -105.973 1.00 53.91 ? 377 TYR B CD2 1 +ATOM 8983 C CE1 . TYR C 1 315 ? -68.017 18.519 -103.589 1.00 61.47 ? 377 TYR B CE1 1 +ATOM 8984 C CE2 . TYR C 1 315 ? -67.592 17.699 -105.797 1.00 54.41 ? 377 TYR B CE2 1 +ATOM 8985 C CZ . TYR C 1 315 ? -67.133 18.221 -104.603 1.00 59.24 ? 377 TYR B CZ 1 +ATOM 8986 O OH . TYR C 1 315 ? -65.788 18.449 -104.417 1.00 62.16 ? 377 TYR B OH 1 +ATOM 8987 N N . CYS C 1 316 ? -72.044 19.340 -107.709 1.00 60.23 ? 378 CYS B N 1 +ATOM 8988 C CA . CYS C 1 316 ? -71.495 20.011 -108.883 1.00 64.14 ? 378 CYS B CA 1 +ATOM 8989 C C . CYS C 1 316 ? -71.924 21.470 -108.973 1.00 66.37 ? 378 CYS B C 1 +ATOM 8990 O O . CYS C 1 316 ? -71.240 22.262 -109.630 1.00 70.83 ? 378 CYS B O 1 +ATOM 8991 C CB . CYS C 1 316 ? -71.888 19.263 -110.164 1.00 70.36 ? 378 CYS B CB 1 +ATOM 8992 S SG . CYS C 1 316 ? -70.989 19.837 -111.649 1.00 88.36 ? 378 CYS B SG 1 +ATOM 8993 N N . ASP C 1 317 ? -73.023 21.850 -108.320 1.00 65.61 ? 379 ASP B N 1 +ATOM 8994 C CA . ASP C 1 317 ? -73.377 23.264 -108.255 1.00 68.45 ? 379 ASP B CA 1 +ATOM 8995 C C . ASP C 1 317 ? -72.292 24.070 -107.555 1.00 64.27 ? 379 ASP B C 1 +ATOM 8996 O O . ASP C 1 317 ? -72.110 25.257 -107.850 1.00 62.78 ? 379 ASP B O 1 +ATOM 8997 C CB . ASP C 1 317 ? -74.719 23.435 -107.548 1.00 73.51 ? 379 ASP B CB 1 +ATOM 8998 C CG . ASP C 1 317 ? -75.885 23.016 -108.415 1.00 70.11 ? 379 ASP B CG 1 +ATOM 8999 O OD1 . ASP C 1 317 ? -75.765 23.111 -109.655 1.00 68.16 ? 379 ASP B OD1 1 +ATOM 9000 O OD2 . ASP C 1 317 ? -76.913 22.581 -107.857 1.00 71.10 ? 379 ASP B OD2 1 +ATOM 9001 N N . THR C 1 318 ? -71.560 23.438 -106.637 1.00 61.26 ? 380 THR B N 1 +ATOM 9002 C CA . THR C 1 318 ? -70.419 24.079 -105.995 1.00 63.41 ? 380 THR B CA 1 +ATOM 9003 C C . THR C 1 318 ? -69.204 24.092 -106.912 1.00 63.07 ? 380 THR B C 1 +ATOM 9004 O O . THR C 1 318 ? -68.484 25.095 -106.987 1.00 58.68 ? 380 THR B O 1 +ATOM 9005 C CB . THR C 1 318 ? -70.074 23.345 -104.698 1.00 58.76 ? 380 THR B CB 1 +ATOM 9006 O OG1 . THR C 1 318 ? -71.254 23.209 -103.900 1.00 60.33 ? 380 THR B OG1 1 +ATOM 9007 C CG2 . THR C 1 318 ? -69.019 24.121 -103.909 1.00 50.77 ? 380 THR B CG2 1 +ATOM 9008 N N . VAL C 1 319 ? -68.966 22.985 -107.618 1.00 61.88 ? 381 VAL B N 1 +ATOM 9009 C CA . VAL C 1 319 ? -67.778 22.877 -108.456 1.00 58.72 ? 381 VAL B CA 1 +ATOM 9010 C C . VAL C 1 319 ? -67.823 23.907 -109.575 1.00 61.72 ? 381 VAL B C 1 +ATOM 9011 O O . VAL C 1 319 ? -66.815 24.553 -109.882 1.00 66.33 ? 381 VAL B O 1 +ATOM 9012 C CB . VAL C 1 319 ? -67.646 21.444 -109.007 1.00 59.01 ? 381 VAL B CB 1 +ATOM 9013 C CG1 . VAL C 1 319 ? -66.366 21.290 -109.816 1.00 59.54 ? 381 VAL B CG1 1 +ATOM 9014 C CG2 . VAL C 1 319 ? -67.684 20.439 -107.873 1.00 56.22 ? 381 VAL B CG2 1 +ATOM 9015 N N . LYS C 1 320 ? -69.006 24.121 -110.159 1.00 57.31 ? 382 LYS B N 1 +ATOM 9016 C CA . LYS C 1 320 ? -69.144 25.033 -111.290 1.00 55.25 ? 382 LYS B CA 1 +ATOM 9017 C C . LYS C 1 320 ? -68.773 26.468 -110.950 1.00 59.52 ? 382 LYS B C 1 +ATOM 9018 O O . LYS C 1 320 ? -68.593 27.275 -111.869 1.00 57.10 ? 382 LYS B O 1 +ATOM 9019 C CB . LYS C 1 320 ? -70.578 24.998 -111.825 1.00 53.71 ? 382 LYS B CB 1 +ATOM 9020 C CG . LYS C 1 320 ? -70.981 23.679 -112.458 1.00 56.04 ? 382 LYS B CG 1 +ATOM 9021 C CD . LYS C 1 320 ? -72.389 23.749 -113.026 1.00 57.07 ? 382 LYS B CD 1 +ATOM 9022 C CE . LYS C 1 320 ? -72.804 22.427 -113.648 1.00 54.63 ? 382 LYS B CE 1 +ATOM 9023 N NZ . LYS C 1 320 ? -74.169 22.509 -114.235 1.00 54.37 ? 382 LYS B NZ 1 +ATOM 9024 N N . GLN C 1 321 ? -68.645 26.803 -109.666 1.00 63.11 ? 383 GLN B N 1 +ATOM 9025 C CA . GLN C 1 321 ? -68.320 28.154 -109.228 1.00 64.05 ? 383 GLN B CA 1 +ATOM 9026 C C . GLN C 1 321 ? -66.932 28.241 -108.602 1.00 69.39 ? 383 GLN B C 1 +ATOM 9027 O O . GLN C 1 321 ? -66.633 29.214 -107.902 1.00 69.40 ? 383 GLN B O 1 +ATOM 9028 C CB . GLN C 1 321 ? -69.381 28.655 -108.248 1.00 60.96 ? 383 GLN B CB 1 +ATOM 9029 C CG . GLN C 1 321 ? -70.789 28.625 -108.819 1.00 61.78 ? 383 GLN B CG 1 +ATOM 9030 C CD . GLN C 1 321 ? -71.849 28.985 -107.798 1.00 67.18 ? 383 GLN B CD 1 +ATOM 9031 O OE1 . GLN C 1 321 ? -71.669 28.779 -106.598 1.00 64.41 ? 383 GLN B OE1 1 +ATOM 9032 N NE2 . GLN C 1 321 ? -72.969 29.515 -108.273 1.00 73.54 ? 383 GLN B NE2 1 +ATOM 9033 N N . ILE C 1 322 ? -66.082 27.241 -108.834 1.00 68.52 ? 384 ILE B N 1 +ATOM 9034 C CA . ILE C 1 322 ? -64.722 27.209 -108.304 1.00 68.09 ? 384 ILE B CA 1 +ATOM 9035 C C . ILE C 1 322 ? -63.745 27.181 -109.474 1.00 71.55 ? 384 ILE B C 1 +ATOM 9036 O O . ILE C 1 322 ? -63.905 26.383 -110.405 1.00 69.45 ? 384 ILE B O 1 +ATOM 9037 C CB . ILE C 1 322 ? -64.505 26.007 -107.362 1.00 61.46 ? 384 ILE B CB 1 +ATOM 9038 C CG1 . ILE C 1 322 ? -64.768 26.405 -105.907 1.00 57.28 ? 384 ILE B CG1 1 +ATOM 9039 C CG2 . ILE C 1 322 ? -63.095 25.455 -107.488 1.00 66.11 ? 384 ILE B CG2 1 +ATOM 9040 C CD1 . ILE C 1 322 ? -66.200 26.750 -105.598 1.00 57.48 ? 384 ILE B CD1 1 +ATOM 9041 N N . TYR C 1 323 ? -62.756 28.074 -109.438 1.00 68.71 ? 385 TYR B N 1 +ATOM 9042 C CA . TYR C 1 323 ? -61.704 28.076 -110.446 1.00 68.80 ? 385 TYR B CA 1 +ATOM 9043 C C . TYR C 1 323 ? -60.835 26.824 -110.293 1.00 73.50 ? 385 TYR B C 1 +ATOM 9044 O O . TYR C 1 323 ? -60.547 26.399 -109.168 1.00 68.54 ? 385 TYR B O 1 +ATOM 9045 C CB . TYR C 1 323 ? -60.854 29.345 -110.310 1.00 65.16 ? 385 TYR B CB 1 +ATOM 9046 C CG . TYR C 1 323 ? -59.636 29.410 -111.208 1.00 69.38 ? 385 TYR B CG 1 +ATOM 9047 C CD1 . TYR C 1 323 ? -59.720 29.945 -112.487 1.00 73.76 ? 385 TYR B CD1 1 +ATOM 9048 C CD2 . TYR C 1 323 ? -58.396 28.954 -110.769 1.00 67.83 ? 385 TYR B CD2 1 +ATOM 9049 C CE1 . TYR C 1 323 ? -58.606 30.006 -113.311 1.00 73.95 ? 385 TYR B CE1 1 +ATOM 9050 C CE2 . TYR C 1 323 ? -57.279 29.014 -111.584 1.00 57.81 ? 385 TYR B CE2 1 +ATOM 9051 C CZ . TYR C 1 323 ? -57.391 29.541 -112.853 1.00 62.78 ? 385 TYR B CZ 1 +ATOM 9052 O OH . TYR C 1 323 ? -56.286 29.608 -113.668 1.00 67.11 ? 385 TYR B OH 1 +ATOM 9053 N N . PRO C 1 324 ? -60.378 26.219 -111.406 1.00 72.88 ? 386 PRO B N 1 +ATOM 9054 C CA . PRO C 1 324 ? -60.594 26.644 -112.793 1.00 71.99 ? 386 PRO B CA 1 +ATOM 9055 C C . PRO C 1 324 ? -61.767 25.961 -113.481 1.00 67.21 ? 386 PRO B C 1 +ATOM 9056 O O . PRO C 1 324 ? -61.747 25.815 -114.701 1.00 70.10 ? 386 PRO B O 1 +ATOM 9057 C CB . PRO C 1 324 ? -59.284 26.247 -113.469 1.00 71.85 ? 386 PRO B CB 1 +ATOM 9058 C CG . PRO C 1 324 ? -58.918 24.973 -112.767 1.00 69.30 ? 386 PRO B CG 1 +ATOM 9059 C CD . PRO C 1 324 ? -59.424 25.096 -111.337 1.00 64.96 ? 386 PRO B CD 1 +ATOM 9060 N N . TYR C 1 325 ? -62.760 25.529 -112.712 1.00 61.29 ? 387 TYR B N 1 +ATOM 9061 C CA . TYR C 1 325 ? -63.950 24.908 -113.277 1.00 63.10 ? 387 TYR B CA 1 +ATOM 9062 C C . TYR C 1 325 ? -65.038 25.918 -113.629 1.00 66.63 ? 387 TYR B C 1 +ATOM 9063 O O . TYR C 1 325 ? -66.107 25.515 -114.104 1.00 65.33 ? 387 TYR B O 1 +ATOM 9064 C CB . TYR C 1 325 ? -64.492 23.855 -112.302 1.00 61.28 ? 387 TYR B CB 1 +ATOM 9065 C CG . TYR C 1 325 ? -63.436 22.861 -111.856 1.00 62.64 ? 387 TYR B CG 1 +ATOM 9066 C CD1 . TYR C 1 325 ? -62.610 23.140 -110.772 1.00 61.12 ? 387 TYR B CD1 1 +ATOM 9067 C CD2 . TYR C 1 325 ? -63.265 21.647 -112.513 1.00 57.22 ? 387 TYR B CD2 1 +ATOM 9068 C CE1 . TYR C 1 325 ? -61.638 22.249 -110.362 1.00 54.79 ? 387 TYR B CE1 1 +ATOM 9069 C CE2 . TYR C 1 325 ? -62.291 20.744 -112.105 1.00 51.79 ? 387 TYR B CE2 1 +ATOM 9070 C CZ . TYR C 1 325 ? -61.483 21.053 -111.028 1.00 48.69 ? 387 TYR B CZ 1 +ATOM 9071 O OH . TYR C 1 325 ? -60.514 20.172 -110.606 1.00 39.71 ? 387 TYR B OH 1 +ATOM 9072 N N . ASN C 1 326 ? -64.783 27.220 -113.438 1.00 71.07 ? 388 ASN B N 1 +ATOM 9073 C CA . ASN C 1 326 ? -65.758 28.248 -113.790 1.00 69.92 ? 388 ASN B CA 1 +ATOM 9074 C C . ASN C 1 326 ? -65.826 28.512 -115.289 1.00 68.96 ? 388 ASN B C 1 +ATOM 9075 O O . ASN C 1 326 ? -66.863 28.979 -115.769 1.00 66.26 ? 388 ASN B O 1 +ATOM 9076 C CB . ASN C 1 326 ? -65.460 29.556 -113.039 1.00 71.24 ? 388 ASN B CB 1 +ATOM 9077 C CG . ASN C 1 326 ? -64.059 30.101 -113.315 1.00 70.31 ? 388 ASN B CG 1 +ATOM 9078 O OD1 . ASN C 1 326 ? -63.137 29.347 -113.622 1.00 73.03 ? 388 ASN B OD1 1 +ATOM 9079 N ND2 . ASN C 1 326 ? -63.901 31.415 -113.211 1.00 72.73 ? 388 ASN B ND2 1 +ATOM 9080 N N . ASN C 1 327 ? -64.752 28.225 -116.033 1.00 76.91 ? 389 ASN B N 1 +ATOM 9081 C CA . ASN C 1 327 ? -64.741 28.425 -117.479 1.00 87.65 ? 389 ASN B CA 1 +ATOM 9082 C C . ASN C 1 327 ? -65.587 27.399 -118.220 1.00 94.22 ? 389 ASN B C 1 +ATOM 9083 O O . ASN C 1 327 ? -65.762 27.535 -119.438 1.00 90.04 ? 389 ASN B O 1 +ATOM 9084 C CB . ASN C 1 327 ? -63.305 28.384 -118.025 1.00 84.09 ? 389 ASN B CB 1 +ATOM 9085 C CG . ASN C 1 327 ? -62.589 27.071 -117.719 1.00 83.17 ? 389 ASN B CG 1 +ATOM 9086 O OD1 . ASN C 1 327 ? -62.890 26.030 -118.307 1.00 75.78 ? 389 ASN B OD1 1 +ATOM 9087 N ND2 . ASN C 1 327 ? -61.615 27.126 -116.817 1.00 83.08 ? 389 ASN B ND2 1 +ATOM 9088 N N . SER C 1 328 ? -66.089 26.374 -117.523 1.00 92.23 ? 390 SER B N 1 +ATOM 9089 C CA . SER C 1 328 ? -66.953 25.333 -118.080 1.00 92.32 ? 390 SER B CA 1 +ATOM 9090 C C . SER C 1 328 ? -66.297 24.579 -119.240 1.00 82.16 ? 390 SER B C 1 +ATOM 9091 O O . SER C 1 328 ? -66.990 23.944 -120.039 1.00 72.02 ? 390 SER B O 1 +ATOM 9092 C CB . SER C 1 328 ? -68.317 25.897 -118.506 1.00 97.82 ? 390 SER B CB 1 +ATOM 9093 O OG . SER C 1 328 ? -69.044 26.409 -117.395 1.00 90.34 ? 390 SER B OG 1 +ATOM 9094 N N . GLN C 1 329 ? -64.970 24.632 -119.347 1.00 78.67 ? 391 GLN B N 1 +ATOM 9095 C CA . GLN C 1 329 ? -64.225 23.843 -120.321 1.00 73.04 ? 391 GLN B CA 1 +ATOM 9096 C C . GLN C 1 329 ? -63.319 22.807 -119.683 1.00 67.41 ? 391 GLN B C 1 +ATOM 9097 O O . GLN C 1 329 ? -63.170 21.716 -120.236 1.00 64.74 ? 391 GLN B O 1 +ATOM 9098 C CB . GLN C 1 329 ? -63.368 24.751 -121.222 1.00 77.39 ? 391 GLN B CB 1 +ATOM 9099 C CG . GLN C 1 329 ? -62.667 24.029 -122.374 1.00 72.87 ? 391 GLN B CG 1 +ATOM 9100 C CD . GLN C 1 329 ? -63.626 23.469 -123.408 1.00 71.78 ? 391 GLN B CD 1 +ATOM 9101 O OE1 . GLN C 1 329 ? -64.678 24.050 -123.679 1.00 83.56 ? 391 GLN B OE1 1 +ATOM 9102 N NE2 . GLN C 1 329 ? -63.258 22.337 -124.003 1.00 55.37 ? 391 GLN B NE2 1 +ATOM 9103 N N . ARG C 1 330 ? -62.729 23.109 -118.525 1.00 70.94 ? 392 ARG B N 1 +ATOM 9104 C CA . ARG C 1 330 ? -61.980 22.094 -117.795 1.00 62.48 ? 392 ARG B CA 1 +ATOM 9105 C C . ARG C 1 330 ? -62.917 21.040 -117.235 1.00 57.78 ? 392 ARG B C 1 +ATOM 9106 O O . ARG C 1 330 ? -62.584 19.850 -117.213 1.00 58.51 ? 392 ARG B O 1 +ATOM 9107 C CB . ARG C 1 330 ? -61.178 22.735 -116.663 1.00 58.08 ? 392 ARG B CB 1 +ATOM 9108 C CG . ARG C 1 330 ? -60.666 21.737 -115.633 1.00 50.82 ? 392 ARG B CG 1 +ATOM 9109 C CD . ARG C 1 330 ? -59.354 21.111 -116.056 1.00 51.75 ? 392 ARG B CD 1 +ATOM 9110 N NE . ARG C 1 330 ? -58.252 22.056 -115.910 1.00 62.25 ? 392 ARG B NE 1 +ATOM 9111 C CZ . ARG C 1 330 ? -57.603 22.277 -114.771 1.00 67.08 ? 392 ARG B CZ 1 +ATOM 9112 N NH1 . ARG C 1 330 ? -57.940 21.614 -113.672 1.00 60.45 ? 392 ARG B NH1 1 +ATOM 9113 N NH2 . ARG C 1 330 ? -56.615 23.163 -114.729 1.00 69.09 ? 392 ARG B NH2 1 +ATOM 9114 N N . LEU C 1 331 ? -64.099 21.462 -116.788 1.00 60.65 ? 393 LEU B N 1 +ATOM 9115 C CA . LEU C 1 331 ? -65.058 20.515 -116.232 1.00 64.62 ? 393 LEU B CA 1 +ATOM 9116 C C . LEU C 1 331 ? -65.460 19.467 -117.261 1.00 55.87 ? 393 LEU B C 1 +ATOM 9117 O O . LEU C 1 331 ? -65.653 18.296 -116.915 1.00 48.05 ? 393 LEU B O 1 +ATOM 9118 C CB . LEU C 1 331 ? -66.291 21.267 -115.724 1.00 74.45 ? 393 LEU B CB 1 +ATOM 9119 C CG . LEU C 1 331 ? -67.386 20.509 -114.973 1.00 62.12 ? 393 LEU B CG 1 +ATOM 9120 C CD1 . LEU C 1 331 ? -66.807 19.775 -113.774 1.00 58.25 ? 393 LEU B CD1 1 +ATOM 9121 C CD2 . LEU C 1 331 ? -68.477 21.471 -114.546 1.00 59.33 ? 393 LEU B CD2 1 +ATOM 9122 N N . LEU C 1 332 ? -65.552 19.862 -118.531 1.00 56.78 ? 394 LEU B N 1 +ATOM 9123 C CA . LEU C 1 332 ? -65.940 18.917 -119.571 1.00 55.47 ? 394 LEU B CA 1 +ATOM 9124 C C . LEU C 1 332 ? -64.894 17.827 -119.745 1.00 54.51 ? 394 LEU B C 1 +ATOM 9125 O O . LEU C 1 332 ? -65.238 16.658 -119.957 1.00 49.67 ? 394 LEU B O 1 +ATOM 9126 C CB . LEU C 1 332 ? -66.169 19.656 -120.884 1.00 55.80 ? 394 LEU B CB 1 +ATOM 9127 C CG . LEU C 1 332 ? -67.289 20.687 -120.847 1.00 53.06 ? 394 LEU B CG 1 +ATOM 9128 C CD1 . LEU C 1 332 ? -67.355 21.430 -122.160 1.00 59.12 ? 394 LEU B CD1 1 +ATOM 9129 C CD2 . LEU C 1 332 ? -68.595 19.988 -120.549 1.00 49.94 ? 394 LEU B CD2 1 +ATOM 9130 N N . ASN C 1 333 ? -63.613 18.188 -119.654 1.00 59.34 ? 395 ASN B N 1 +ATOM 9131 C CA . ASN C 1 333 ? -62.562 17.182 -119.732 1.00 58.15 ? 395 ASN B CA 1 +ATOM 9132 C C . ASN C 1 333 ? -62.629 16.215 -118.557 1.00 54.60 ? 395 ASN B C 1 +ATOM 9133 O O . ASN C 1 333 ? -62.271 15.040 -118.701 1.00 56.33 ? 395 ASN B O 1 +ATOM 9134 C CB . ASN C 1 333 ? -61.189 17.852 -119.785 1.00 59.19 ? 395 ASN B CB 1 +ATOM 9135 C CG . ASN C 1 333 ? -60.958 18.610 -121.071 1.00 62.09 ? 395 ASN B CG 1 +ATOM 9136 O OD1 . ASN C 1 333 ? -60.424 18.064 -122.037 1.00 64.51 ? 395 ASN B OD1 1 +ATOM 9137 N ND2 . ASN C 1 333 ? -61.345 19.883 -121.087 1.00 65.00 ? 395 ASN B ND2 1 +ATOM 9138 N N . VAL C 1 334 ? -63.073 16.687 -117.389 1.00 49.91 ? 396 VAL B N 1 +ATOM 9139 C CA . VAL C 1 334 ? -63.232 15.785 -116.253 1.00 48.92 ? 396 VAL B CA 1 +ATOM 9140 C C . VAL C 1 334 ? -64.410 14.851 -116.479 1.00 49.87 ? 396 VAL B C 1 +ATOM 9141 O O . VAL C 1 334 ? -64.397 13.699 -116.024 1.00 46.59 ? 396 VAL B O 1 +ATOM 9142 C CB . VAL C 1 334 ? -63.391 16.578 -114.945 1.00 45.11 ? 396 VAL B CB 1 +ATOM 9143 C CG1 . VAL C 1 334 ? -63.384 15.634 -113.748 1.00 38.00 ? 396 VAL B CG1 1 +ATOM 9144 C CG2 . VAL C 1 334 ? -62.294 17.610 -114.822 1.00 51.61 ? 396 VAL B CG2 1 +ATOM 9145 N N . ILE C 1 335 ? -65.443 15.320 -117.178 1.00 51.81 ? 397 ILE B N 1 +ATOM 9146 C CA . ILE C 1 335 ? -66.577 14.454 -117.483 1.00 53.23 ? 397 ILE B CA 1 +ATOM 9147 C C . ILE C 1 335 ? -66.125 13.288 -118.355 1.00 48.73 ? 397 ILE B C 1 +ATOM 9148 O O . ILE C 1 335 ? -66.464 12.127 -118.098 1.00 44.33 ? 397 ILE B O 1 +ATOM 9149 C CB . ILE C 1 335 ? -67.703 15.257 -118.158 1.00 56.45 ? 397 ILE B CB 1 +ATOM 9150 C CG1 . ILE C 1 335 ? -68.110 16.462 -117.303 1.00 44.07 ? 397 ILE B CG1 1 +ATOM 9151 C CG2 . ILE C 1 335 ? -68.911 14.361 -118.385 1.00 50.24 ? 397 ILE B CG2 1 +ATOM 9152 C CD1 . ILE C 1 335 ? -68.837 16.104 -116.043 1.00 45.02 ? 397 ILE B CD1 1 +ATOM 9153 N N . ASP C 1 336 ? -65.336 13.580 -119.393 1.00 54.62 ? 398 ASP B N 1 +ATOM 9154 C CA . ASP C 1 336 ? -64.816 12.513 -120.241 1.00 52.47 ? 398 ASP B CA 1 +ATOM 9155 C C . ASP C 1 336 ? -64.014 11.512 -119.428 1.00 45.25 ? 398 ASP B C 1 +ATOM 9156 O O . ASP C 1 336 ? -64.212 10.299 -119.560 1.00 47.34 ? 398 ASP B O 1 +ATOM 9157 C CB . ASP C 1 336 ? -63.958 13.096 -121.364 1.00 56.20 ? 398 ASP B CB 1 +ATOM 9158 C CG . ASP C 1 336 ? -64.778 13.846 -122.403 1.00 62.72 ? 398 ASP B CG 1 +ATOM 9159 O OD1 . ASP C 1 336 ? -65.910 14.285 -122.091 1.00 66.65 ? 398 ASP B OD1 1 +ATOM 9160 O OD2 . ASP C 1 336 ? -64.280 13.997 -123.539 1.00 67.26 ? 398 ASP B OD2 1 +ATOM 9161 N N . MET C 1 337 ? -63.146 12.004 -118.538 1.00 44.56 ? 399 MET B N 1 +ATOM 9162 C CA . MET C 1 337 ? -62.353 11.112 -117.699 1.00 44.32 ? 399 MET B CA 1 +ATOM 9163 C C . MET C 1 337 ? -63.244 10.209 -116.856 1.00 45.75 ? 399 MET B C 1 +ATOM 9164 O O . MET C 1 337 ? -62.921 9.036 -116.639 1.00 49.13 ? 399 MET B O 1 +ATOM 9165 C CB . MET C 1 337 ? -61.424 11.923 -116.800 1.00 44.18 ? 399 MET B CB 1 +ATOM 9166 C CG . MET C 1 337 ? -60.487 11.077 -115.970 1.00 41.18 ? 399 MET B CG 1 +ATOM 9167 S SD . MET C 1 337 ? -59.289 12.065 -115.063 1.00 53.11 ? 399 MET B SD 1 +ATOM 9168 C CE . MET C 1 337 ? -60.371 13.123 -114.113 1.00 54.77 ? 399 MET B CE 1 +ATOM 9169 N N . ALA C 1 338 ? -64.369 10.737 -116.368 1.00 43.78 ? 400 ALA B N 1 +ATOM 9170 C CA . ALA C 1 338 ? -65.306 9.899 -115.625 1.00 39.84 ? 400 ALA B CA 1 +ATOM 9171 C C . ALA C 1 338 ? -65.901 8.824 -116.521 1.00 38.00 ? 400 ALA B C 1 +ATOM 9172 O O . ALA C 1 338 ? -66.063 7.671 -116.103 1.00 38.00 ? 400 ALA B O 1 +ATOM 9173 C CB . ALA C 1 338 ? -66.409 10.757 -115.008 1.00 41.78 ? 400 ALA B CB 1 +ATOM 9174 N N . ILE C 1 339 ? -66.241 9.186 -117.757 1.00 41.07 ? 401 ILE B N 1 +ATOM 9175 C CA . ILE C 1 339 ? -66.780 8.207 -118.692 1.00 38.47 ? 401 ILE B CA 1 +ATOM 9176 C C . ILE C 1 339 ? -65.761 7.109 -118.944 1.00 38.00 ? 401 ILE B C 1 +ATOM 9177 O O . ILE C 1 339 ? -66.080 5.915 -118.901 1.00 38.09 ? 401 ILE B O 1 +ATOM 9178 C CB . ILE C 1 339 ? -67.200 8.899 -119.998 1.00 38.00 ? 401 ILE B CB 1 +ATOM 9179 C CG1 . ILE C 1 339 ? -68.310 9.909 -119.713 1.00 38.00 ? 401 ILE B CG1 1 +ATOM 9180 C CG2 . ILE C 1 339 ? -67.658 7.874 -121.004 1.00 41.91 ? 401 ILE B CG2 1 +ATOM 9181 C CD1 . ILE C 1 339 ? -68.730 10.705 -120.908 1.00 39.00 ? 401 ILE B CD1 1 +ATOM 9182 N N . PHE C 1 340 ? -64.511 7.500 -119.193 1.00 43.13 ? 402 PHE B N 1 +ATOM 9183 C CA . PHE C 1 340 ? -63.467 6.519 -119.466 1.00 46.68 ? 402 PHE B CA 1 +ATOM 9184 C C . PHE C 1 340 ? -63.197 5.638 -118.249 1.00 42.83 ? 402 PHE B C 1 +ATOM 9185 O O . PHE C 1 340 ? -62.924 4.441 -118.396 1.00 46.93 ? 402 PHE B O 1 +ATOM 9186 C CB . PHE C 1 340 ? -62.193 7.232 -119.925 1.00 46.96 ? 402 PHE B CB 1 +ATOM 9187 C CG . PHE C 1 340 ? -61.046 6.306 -120.212 1.00 42.19 ? 402 PHE B CG 1 +ATOM 9188 C CD1 . PHE C 1 340 ? -61.122 5.387 -121.244 1.00 45.36 ? 402 PHE B CD1 1 +ATOM 9189 C CD2 . PHE C 1 340 ? -59.889 6.363 -119.457 1.00 42.25 ? 402 PHE B CD2 1 +ATOM 9190 C CE1 . PHE C 1 340 ? -60.068 4.536 -121.512 1.00 46.67 ? 402 PHE B CE1 1 +ATOM 9191 C CE2 . PHE C 1 340 ? -58.831 5.514 -119.718 1.00 43.69 ? 402 PHE B CE2 1 +ATOM 9192 C CZ . PHE C 1 340 ? -58.919 4.601 -120.748 1.00 45.12 ? 402 PHE B CZ 1 +ATOM 9193 N N . ASP C 1 341 ? -63.269 6.202 -117.041 1.00 38.00 ? 403 ASP B N 1 +ATOM 9194 C CA . ASP C 1 341 ? -63.036 5.390 -115.850 1.00 42.49 ? 403 ASP B CA 1 +ATOM 9195 C C . ASP C 1 341 ? -64.228 4.490 -115.552 1.00 38.93 ? 403 ASP B C 1 +ATOM 9196 O O . ASP C 1 341 ? -64.055 3.370 -115.057 1.00 40.30 ? 403 ASP B O 1 +ATOM 9197 C CB . ASP C 1 341 ? -62.720 6.273 -114.647 1.00 45.76 ? 403 ASP B CB 1 +ATOM 9198 C CG . ASP C 1 341 ? -61.363 6.928 -114.747 1.00 45.74 ? 403 ASP B CG 1 +ATOM 9199 O OD1 . ASP C 1 341 ? -60.419 6.303 -115.280 1.00 38.00 ? 403 ASP B OD1 1 +ATOM 9200 O OD2 . ASP C 1 341 ? -61.249 8.078 -114.281 1.00 54.02 ? 403 ASP B OD2 1 +ATOM 9201 N N . PHE C 1 342 ? -65.448 4.973 -115.800 1.00 38.00 ? 404 PHE B N 1 +ATOM 9202 C CA . PHE C 1 342 ? -66.612 4.129 -115.554 1.00 39.06 ? 404 PHE B CA 1 +ATOM 9203 C C . PHE C 1 342 ? -66.646 2.945 -116.509 1.00 40.55 ? 404 PHE B C 1 +ATOM 9204 O O . PHE C 1 342 ? -67.004 1.830 -116.111 1.00 46.22 ? 404 PHE B O 1 +ATOM 9205 C CB . PHE C 1 342 ? -67.905 4.933 -115.679 1.00 39.67 ? 404 PHE B CB 1 +ATOM 9206 C CG . PHE C 1 342 ? -69.154 4.092 -115.565 1.00 44.01 ? 404 PHE B CG 1 +ATOM 9207 C CD1 . PHE C 1 342 ? -69.383 3.310 -114.440 1.00 49.56 ? 404 PHE B CD1 1 +ATOM 9208 C CD2 . PHE C 1 342 ? -70.084 4.063 -116.589 1.00 42.32 ? 404 PHE B CD2 1 +ATOM 9209 C CE1 . PHE C 1 342 ? -70.527 2.528 -114.337 1.00 47.57 ? 404 PHE B CE1 1 +ATOM 9210 C CE2 . PHE C 1 342 ? -71.229 3.283 -116.491 1.00 44.01 ? 404 PHE B CE2 1 +ATOM 9211 C CZ . PHE C 1 342 ? -71.450 2.517 -115.363 1.00 42.24 ? 404 PHE B CZ 1 +ATOM 9212 N N . LEU C 1 343 ? -66.248 3.155 -117.764 1.00 38.00 ? 405 LEU B N 1 +ATOM 9213 C CA . LEU C 1 343 ? -66.245 2.053 -118.718 1.00 38.00 ? 405 LEU B CA 1 +ATOM 9214 C C . LEU C 1 343 ? -65.316 0.936 -118.265 1.00 38.00 ? 405 LEU B C 1 +ATOM 9215 O O . LEU C 1 343 ? -65.653 -0.246 -118.386 1.00 38.00 ? 405 LEU B O 1 +ATOM 9216 C CB . LEU C 1 343 ? -65.853 2.568 -120.097 1.00 38.00 ? 405 LEU B CB 1 +ATOM 9217 C CG . LEU C 1 343 ? -66.970 3.349 -120.782 1.00 38.00 ? 405 LEU B CG 1 +ATOM 9218 C CD1 . LEU C 1 343 ? -66.414 4.069 -121.978 1.00 40.97 ? 405 LEU B CD1 1 +ATOM 9219 C CD2 . LEU C 1 343 ? -68.093 2.417 -121.200 1.00 38.00 ? 405 LEU B CD2 1 +ATOM 9220 N N . ILE C 1 344 ? -64.164 1.289 -117.691 1.00 40.50 ? 406 ILE B N 1 +ATOM 9221 C CA . ILE C 1 344 ? -63.211 0.286 -117.226 1.00 39.25 ? 406 ILE B CA 1 +ATOM 9222 C C . ILE C 1 344 ? -63.358 -0.025 -115.743 1.00 38.00 ? 406 ILE B C 1 +ATOM 9223 O O . ILE C 1 344 ? -62.740 -0.990 -115.266 1.00 44.40 ? 406 ILE B O 1 +ATOM 9224 C CB . ILE C 1 344 ? -61.753 0.706 -117.517 1.00 38.00 ? 406 ILE B CB 1 +ATOM 9225 C CG1 . ILE C 1 344 ? -61.382 1.942 -116.709 1.00 38.00 ? 406 ILE B CG1 1 +ATOM 9226 C CG2 . ILE C 1 344 ? -61.557 0.987 -118.994 1.00 38.00 ? 406 ILE B CG2 1 +ATOM 9227 C CD1 . ILE C 1 344 ? -59.991 2.436 -117.006 1.00 38.00 ? 406 ILE B CD1 1 +ATOM 9228 N N . GLY C 1 345 ? -64.142 0.750 -115.002 1.00 38.00 ? 407 GLY B N 1 +ATOM 9229 C CA . GLY C 1 345 ? -64.267 0.514 -113.574 1.00 39.73 ? 407 GLY B CA 1 +ATOM 9230 C C . GLY C 1 345 ? -63.036 0.906 -112.785 1.00 39.30 ? 407 GLY B C 1 +ATOM 9231 O O . GLY C 1 345 ? -62.627 0.182 -111.866 1.00 38.00 ? 407 GLY B O 1 +ATOM 9232 N N . ASN C 1 346 ? -62.449 2.055 -113.104 1.00 38.69 ? 408 ASN B N 1 +ATOM 9233 C CA . ASN C 1 346 ? -61.250 2.545 -112.428 1.00 40.40 ? 408 ASN B CA 1 +ATOM 9234 C C . ASN C 1 346 ? -61.718 3.544 -111.378 1.00 46.44 ? 408 ASN B C 1 +ATOM 9235 O O . ASN C 1 346 ? -61.897 4.731 -111.657 1.00 48.85 ? 408 ASN B O 1 +ATOM 9236 C CB . ASN C 1 346 ? -60.272 3.173 -113.413 1.00 39.77 ? 408 ASN B CB 1 +ATOM 9237 C CG . ASN C 1 346 ? -58.915 3.471 -112.785 1.00 39.11 ? 408 ASN B CG 1 +ATOM 9238 O OD1 . ASN C 1 346 ? -58.405 2.692 -111.977 1.00 38.00 ? 408 ASN B OD1 1 +ATOM 9239 N ND2 . ASN C 1 346 ? -58.329 4.606 -113.151 1.00 40.23 ? 408 ASN B ND2 1 +ATOM 9240 N N . MET C 1 347 ? -61.950 3.047 -110.161 1.00 42.44 ? 409 MET B N 1 +ATOM 9241 C CA . MET C 1 347 ? -62.339 3.937 -109.072 1.00 45.44 ? 409 MET B CA 1 +ATOM 9242 C C . MET C 1 347 ? -61.164 4.777 -108.586 1.00 43.18 ? 409 MET B C 1 +ATOM 9243 O O . MET C 1 347 ? -61.367 5.864 -108.036 1.00 51.89 ? 409 MET B O 1 +ATOM 9244 C CB . MET C 1 347 ? -62.940 3.136 -107.919 1.00 48.44 ? 409 MET B CB 1 +ATOM 9245 C CG . MET C 1 347 ? -63.867 2.017 -108.361 1.00 49.12 ? 409 MET B CG 1 +ATOM 9246 S SD . MET C 1 347 ? -64.705 1.246 -106.962 1.00 44.41 ? 409 MET B SD 1 +ATOM 9247 C CE . MET C 1 347 ? -65.359 -0.240 -107.731 1.00 47.70 ? 409 MET B CE 1 +ATOM 9248 N N . ASP C 1 348 ? -59.938 4.303 -108.787 1.00 38.75 ? 410 ASP B N 1 +ATOM 9249 C CA . ASP C 1 348 ? -58.745 4.958 -108.251 1.00 40.60 ? 410 ASP B CA 1 +ATOM 9250 C C . ASP C 1 348 ? -58.219 6.004 -109.238 1.00 46.92 ? 410 ASP B C 1 +ATOM 9251 O O . ASP C 1 348 ? -57.182 5.841 -109.886 1.00 55.56 ? 410 ASP B O 1 +ATOM 9252 C CB . ASP C 1 348 ? -57.685 3.913 -107.931 1.00 40.48 ? 410 ASP B CB 1 +ATOM 9253 C CG . ASP C 1 348 ? -56.473 4.496 -107.242 1.00 46.96 ? 410 ASP B CG 1 +ATOM 9254 O OD1 . ASP C 1 348 ? -56.445 5.724 -107.026 1.00 52.11 ? 410 ASP B OD1 1 +ATOM 9255 O OD2 . ASP C 1 348 ? -55.537 3.727 -106.932 1.00 49.44 ? 410 ASP B OD2 1 +ATOM 9256 N N . ARG C 1 349 ? -58.943 7.116 -109.318 1.00 43.72 ? 411 ARG B N 1 +ATOM 9257 C CA . ARG C 1 349 ? -58.509 8.287 -110.078 1.00 45.23 ? 411 ARG B CA 1 +ATOM 9258 C C . ARG C 1 349 ? -58.497 9.495 -109.142 1.00 47.19 ? 411 ARG B C 1 +ATOM 9259 O O . ARG C 1 349 ? -59.323 10.406 -109.259 1.00 43.66 ? 411 ARG B O 1 +ATOM 9260 C CB . ARG C 1 349 ? -59.401 8.522 -111.310 1.00 42.17 ? 411 ARG B CB 1 +ATOM 9261 C CG . ARG C 1 349 ? -58.876 9.624 -112.248 1.00 49.42 ? 411 ARG B CG 1 +ATOM 9262 C CD . ARG C 1 349 ? -58.476 9.087 -113.618 1.00 47.13 ? 411 ARG B CD 1 +ATOM 9263 N NE . ARG C 1 349 ? -57.217 8.352 -113.625 1.00 46.82 ? 411 ARG B NE 1 +ATOM 9264 C CZ . ARG C 1 349 ? -56.793 7.627 -114.655 1.00 45.56 ? 411 ARG B CZ 1 +ATOM 9265 N NH1 . ARG C 1 349 ? -57.535 7.531 -115.752 1.00 38.00 ? 411 ARG B NH1 1 +ATOM 9266 N NH2 . ARG C 1 349 ? -55.632 6.991 -114.588 1.00 50.37 ? 411 ARG B NH2 1 +ATOM 9267 N N . HIS C 1 350 ? -57.548 9.492 -108.200 1.00 45.10 ? 412 HIS B N 1 +ATOM 9268 C CA . HIS C 1 350 ? -57.434 10.597 -107.254 1.00 45.10 ? 412 HIS B CA 1 +ATOM 9269 C C . HIS C 1 350 ? -56.836 11.847 -107.896 1.00 46.21 ? 412 HIS B C 1 +ATOM 9270 O O . HIS C 1 350 ? -57.182 12.968 -107.504 1.00 47.38 ? 412 HIS B O 1 +ATOM 9271 C CB . HIS C 1 350 ? -56.617 10.172 -106.030 1.00 44.52 ? 412 HIS B CB 1 +ATOM 9272 C CG . HIS C 1 350 ? -55.327 9.477 -106.347 1.00 47.58 ? 412 HIS B CG 1 +ATOM 9273 N ND1 . HIS C 1 350 ? -54.753 9.483 -107.599 1.00 50.24 ? 412 HIS B ND1 1 +ATOM 9274 C CD2 . HIS C 1 350 ? -54.498 8.752 -105.558 1.00 50.43 ? 412 HIS B CD2 1 +ATOM 9275 C CE1 . HIS C 1 350 ? -53.628 8.791 -107.570 1.00 51.12 ? 412 HIS B CE1 1 +ATOM 9276 N NE2 . HIS C 1 350 ? -53.451 8.335 -106.343 1.00 52.44 ? 412 HIS B NE2 1 +ATOM 9277 N N . HIS C 1 351 ? -55.945 11.687 -108.868 1.00 46.17 ? 413 HIS B N 1 +ATOM 9278 C CA . HIS C 1 351 ? -55.281 12.819 -109.494 1.00 47.09 ? 413 HIS B CA 1 +ATOM 9279 C C . HIS C 1 351 ? -55.223 12.617 -110.999 1.00 48.70 ? 413 HIS B C 1 +ATOM 9280 O O . HIS C 1 351 ? -55.043 11.494 -111.484 1.00 47.44 ? 413 HIS B O 1 +ATOM 9281 C CB . HIS C 1 351 ? -53.859 13.023 -108.947 1.00 50.23 ? 413 HIS B CB 1 +ATOM 9282 C CG . HIS C 1 351 ? -53.810 13.446 -107.510 1.00 47.25 ? 413 HIS B CG 1 +ATOM 9283 N ND1 . HIS C 1 351 ? -54.090 12.588 -106.468 1.00 46.41 ? 413 HIS B ND1 1 +ATOM 9284 C CD2 . HIS C 1 351 ? -53.489 14.634 -106.943 1.00 44.80 ? 413 HIS B CD2 1 +ATOM 9285 C CE1 . HIS C 1 351 ? -53.959 13.233 -105.322 1.00 46.72 ? 413 HIS B CE1 1 +ATOM 9286 N NE2 . HIS C 1 351 ? -53.595 14.476 -105.582 1.00 47.78 ? 413 HIS B NE2 1 +ATOM 9287 N N . TYR C 1 352 ? -55.398 13.712 -111.729 1.00 48.64 ? 414 TYR B N 1 +ATOM 9288 C CA . TYR C 1 352 ? -55.213 13.741 -113.170 1.00 50.62 ? 414 TYR B CA 1 +ATOM 9289 C C . TYR C 1 352 ? -54.126 14.756 -113.502 1.00 50.57 ? 414 TYR B C 1 +ATOM 9290 O O . TYR C 1 352 ? -54.080 15.839 -112.911 1.00 50.61 ? 414 TYR B O 1 +ATOM 9291 C CB . TYR C 1 352 ? -56.527 14.083 -113.892 1.00 49.47 ? 414 TYR B CB 1 +ATOM 9292 C CG . TYR C 1 352 ? -57.097 15.455 -113.594 1.00 48.98 ? 414 TYR B CG 1 +ATOM 9293 C CD1 . TYR C 1 352 ? -57.956 15.666 -112.523 1.00 48.42 ? 414 TYR B CD1 1 +ATOM 9294 C CD2 . TYR C 1 352 ? -56.792 16.538 -114.407 1.00 52.84 ? 414 TYR B CD2 1 +ATOM 9295 C CE1 . TYR C 1 352 ? -58.480 16.927 -112.262 1.00 52.63 ? 414 TYR B CE1 1 +ATOM 9296 C CE2 . TYR C 1 352 ? -57.309 17.794 -114.157 1.00 54.22 ? 414 TYR B CE2 1 +ATOM 9297 C CZ . TYR C 1 352 ? -58.152 17.986 -113.088 1.00 54.33 ? 414 TYR B CZ 1 +ATOM 9298 O OH . TYR C 1 352 ? -58.660 19.245 -112.854 1.00 51.90 ? 414 TYR B OH 1 +ATOM 9299 N N . GLU C 1 353 ? -53.227 14.390 -114.414 1.00 48.68 ? 415 GLU B N 1 +ATOM 9300 C CA . GLU C 1 353 ? -52.106 15.244 -114.783 1.00 49.81 ? 415 GLU B CA 1 +ATOM 9301 C C . GLU C 1 353 ? -52.415 16.027 -116.052 1.00 46.73 ? 415 GLU B C 1 +ATOM 9302 O O . GLU C 1 353 ? -53.187 15.581 -116.905 1.00 46.79 ? 415 GLU B O 1 +ATOM 9303 C CB . GLU C 1 353 ? -50.829 14.422 -114.977 1.00 52.95 ? 415 GLU B CB 1 +ATOM 9304 C CG . GLU C 1 353 ? -50.279 13.819 -113.693 1.00 56.70 ? 415 GLU B CG 1 +ATOM 9305 C CD . GLU C 1 353 ? -48.884 13.251 -113.861 1.00 51.44 ? 415 GLU B CD 1 +ATOM 9306 O OE1 . GLU C 1 353 ? -48.252 13.511 -114.906 1.00 48.52 ? 415 GLU B OE1 1 +ATOM 9307 O OE2 . GLU C 1 353 ? -48.415 12.545 -112.945 1.00 54.47 ? 415 GLU B OE2 1 +ATOM 9308 N N . MET C 1 354 ? -51.784 17.196 -116.177 1.00 52.96 ? 416 MET B N 1 +ATOM 9309 C CA . MET C 1 354 ? -51.980 18.080 -117.319 1.00 55.25 ? 416 MET B CA 1 +ATOM 9310 C C . MET C 1 354 ? -50.641 18.633 -117.786 1.00 52.83 ? 416 MET B C 1 +ATOM 9311 O O . MET C 1 354 ? -49.692 18.748 -117.004 1.00 51.72 ? 416 MET B O 1 +ATOM 9312 C CB . MET C 1 354 ? -52.912 19.256 -116.990 1.00 54.24 ? 416 MET B CB 1 +ATOM 9313 C CG . MET C 1 354 ? -54.261 18.857 -116.433 1.00 54.16 ? 416 MET B CG 1 +ATOM 9314 S SD . MET C 1 354 ? -55.335 20.282 -116.188 1.00 58.55 ? 416 MET B SD 1 +ATOM 9315 C CE . MET C 1 354 ? -55.184 21.094 -117.778 1.00 57.23 ? 416 MET B CE 1 +ATOM 9316 N N . PHE C 1 355 ? -50.579 18.993 -119.068 1.00 51.68 ? 417 PHE B N 1 +ATOM 9317 C CA . PHE C 1 355 ? -49.417 19.672 -119.627 1.00 50.45 ? 417 PHE B CA 1 +ATOM 9318 C C . PHE C 1 355 ? -49.571 21.165 -119.381 1.00 50.95 ? 417 PHE B C 1 +ATOM 9319 O O . PHE C 1 355 ? -50.553 21.774 -119.820 1.00 51.37 ? 417 PHE B O 1 +ATOM 9320 C CB . PHE C 1 355 ? -49.266 19.395 -121.123 1.00 46.78 ? 417 PHE B CB 1 +ATOM 9321 C CG . PHE C 1 355 ? -48.805 18.004 -121.442 1.00 44.02 ? 417 PHE B CG 1 +ATOM 9322 C CD1 . PHE C 1 355 ? -47.531 17.588 -121.095 1.00 48.94 ? 417 PHE B CD1 1 +ATOM 9323 C CD2 . PHE C 1 355 ? -49.638 17.117 -122.104 1.00 45.41 ? 417 PHE B CD2 1 +ATOM 9324 C CE1 . PHE C 1 355 ? -47.101 16.306 -121.390 1.00 52.63 ? 417 PHE B CE1 1 +ATOM 9325 C CE2 . PHE C 1 355 ? -49.214 15.835 -122.405 1.00 43.34 ? 417 PHE B CE2 1 +ATOM 9326 C CZ . PHE C 1 355 ? -47.944 15.428 -122.048 1.00 47.12 ? 417 PHE B CZ 1 +ATOM 9327 N N . THR C 1 356 ? -48.599 21.749 -118.682 1.00 48.88 ? 418 THR B N 1 +ATOM 9328 C CA . THR C 1 356 ? -48.718 23.143 -118.286 1.00 53.92 ? 418 THR B CA 1 +ATOM 9329 C C . THR C 1 356 ? -48.712 24.085 -119.485 1.00 55.67 ? 418 THR B C 1 +ATOM 9330 O O . THR C 1 356 ? -49.252 25.192 -119.391 1.00 58.28 ? 418 THR B O 1 +ATOM 9331 C CB . THR C 1 356 ? -47.598 23.499 -117.310 1.00 47.52 ? 418 THR B CB 1 +ATOM 9332 O OG1 . THR C 1 356 ? -47.624 24.903 -117.046 1.00 57.44 ? 418 THR B OG1 1 +ATOM 9333 C CG2 . THR C 1 356 ? -46.257 23.142 -117.904 1.00 47.53 ? 418 THR B CG2 1 +ATOM 9334 N N . LYS C 1 357 ? -48.125 23.667 -120.609 1.00 49.55 ? 419 LYS B N 1 +ATOM 9335 C CA . LYS C 1 357 ? -48.091 24.525 -121.787 1.00 50.83 ? 419 LYS B CA 1 +ATOM 9336 C C . LYS C 1 357 ? -49.483 24.733 -122.369 1.00 57.55 ? 419 LYS B C 1 +ATOM 9337 O O . LYS C 1 357 ? -49.758 25.786 -122.958 1.00 60.70 ? 419 LYS B O 1 +ATOM 9338 C CB . LYS C 1 357 ? -47.151 23.931 -122.839 1.00 51.29 ? 419 LYS B CB 1 +ATOM 9339 C CG . LYS C 1 357 ? -47.059 24.728 -124.130 1.00 57.62 ? 419 LYS B CG 1 +ATOM 9340 C CD . LYS C 1 357 ? -45.928 24.224 -125.014 1.00 60.52 ? 419 LYS B CD 1 +ATOM 9341 C CE . LYS C 1 357 ? -45.860 24.998 -126.321 1.00 62.52 ? 419 LYS B CE 1 +ATOM 9342 N NZ . LYS C 1 357 ? -44.694 24.602 -127.151 1.00 54.03 ? 419 LYS B NZ 1 +ATOM 9343 N N . PHE C 1 358 ? -50.378 23.762 -122.194 1.00 55.91 ? 420 PHE B N 1 +ATOM 9344 C CA . PHE C 1 358 ? -51.685 23.804 -122.831 1.00 60.04 ? 420 PHE B CA 1 +ATOM 9345 C C . PHE C 1 358 ? -52.731 24.555 -122.021 1.00 63.27 ? 420 PHE B C 1 +ATOM 9346 O O . PHE C 1 358 ? -53.831 24.794 -122.534 1.00 71.66 ? 420 PHE B O 1 +ATOM 9347 C CB . PHE C 1 358 ? -52.178 22.386 -123.121 1.00 59.01 ? 420 PHE B CB 1 +ATOM 9348 C CG . PHE C 1 358 ? -51.321 21.645 -124.105 1.00 56.07 ? 420 PHE B CG 1 +ATOM 9349 C CD1 . PHE C 1 358 ? -50.661 22.325 -125.115 1.00 53.01 ? 420 PHE B CD1 1 +ATOM 9350 C CD2 . PHE C 1 358 ? -51.194 20.270 -124.036 1.00 54.34 ? 420 PHE B CD2 1 +ATOM 9351 C CE1 . PHE C 1 358 ? -49.881 21.649 -126.026 1.00 55.34 ? 420 PHE B CE1 1 +ATOM 9352 C CE2 . PHE C 1 358 ? -50.414 19.587 -124.948 1.00 52.72 ? 420 PHE B CE2 1 +ATOM 9353 C CZ . PHE C 1 358 ? -49.760 20.278 -125.945 1.00 55.23 ? 420 PHE B CZ 1 +ATOM 9354 N N . GLY C 1 359 ? -52.441 24.898 -120.773 1.00 52.90 ? 421 GLY B N 1 +ATOM 9355 C CA . GLY C 1 359 ? -53.322 25.775 -120.039 1.00 57.18 ? 421 GLY B CA 1 +ATOM 9356 C C . GLY C 1 359 ? -54.520 25.049 -119.460 1.00 65.00 ? 421 GLY B C 1 +ATOM 9357 O O . GLY C 1 359 ? -54.637 23.820 -119.507 1.00 66.91 ? 421 GLY B O 1 +ATOM 9358 N N . ASP C 1 360 ? -55.447 25.852 -118.928 1.00 62.91 ? 422 ASP B N 1 +ATOM 9359 C CA . ASP C 1 360 ? -56.624 25.304 -118.262 1.00 64.23 ? 422 ASP B CA 1 +ATOM 9360 C C . ASP C 1 360 ? -57.498 24.504 -119.216 1.00 69.47 ? 422 ASP B C 1 +ATOM 9361 O O . ASP C 1 360 ? -58.186 23.568 -118.791 1.00 70.18 ? 422 ASP B O 1 +ATOM 9362 C CB . ASP C 1 360 ? -57.436 26.433 -117.639 1.00 61.01 ? 422 ASP B CB 1 +ATOM 9363 C CG . ASP C 1 360 ? -56.572 27.407 -116.885 1.00 72.38 ? 422 ASP B CG 1 +ATOM 9364 O OD1 . ASP C 1 360 ? -55.869 28.206 -117.542 1.00 71.12 ? 422 ASP B OD1 1 +ATOM 9365 O OD2 . ASP C 1 360 ? -56.580 27.361 -115.640 1.00 84.71 ? 422 ASP B OD2 1 +ATOM 9366 N N . ASP C 1 361 ? -57.492 24.851 -120.497 1.00 68.09 ? 423 ASP B N 1 +ATOM 9367 C CA . ASP C 1 361 ? -58.282 24.120 -121.473 1.00 69.95 ? 423 ASP B CA 1 +ATOM 9368 C C . ASP C 1 361 ? -57.553 22.907 -122.030 1.00 66.44 ? 423 ASP B C 1 +ATOM 9369 O O . ASP C 1 361 ? -58.121 22.195 -122.863 1.00 69.31 ? 423 ASP B O 1 +ATOM 9370 C CB . ASP C 1 361 ? -58.706 25.050 -122.614 1.00 74.86 ? 423 ASP B CB 1 +ATOM 9371 C CG . ASP C 1 361 ? -59.670 26.134 -122.156 1.00 84.95 ? 423 ASP B CG 1 +ATOM 9372 O OD1 . ASP C 1 361 ? -60.349 25.938 -121.122 1.00 84.89 ? 423 ASP B OD1 1 +ATOM 9373 O OD2 . ASP C 1 361 ? -59.741 27.188 -122.825 1.00 81.64 ? 423 ASP B OD2 1 +ATOM 9374 N N . GLY C 1 362 ? -56.326 22.647 -121.582 1.00 62.36 ? 424 GLY B N 1 +ATOM 9375 C CA . GLY C 1 362 ? -55.600 21.491 -122.068 1.00 61.16 ? 424 GLY B CA 1 +ATOM 9376 C C . GLY C 1 362 ? -56.273 20.192 -121.669 1.00 62.78 ? 424 GLY B C 1 +ATOM 9377 O O . GLY C 1 362 ? -57.019 20.121 -120.692 1.00 66.49 ? 424 GLY B O 1 +ATOM 9378 N N . PHE C 1 363 ? -56.018 19.152 -122.456 1.00 57.40 ? 425 PHE B N 1 +ATOM 9379 C CA . PHE C 1 363 ? -56.600 17.846 -122.190 1.00 54.77 ? 425 PHE B CA 1 +ATOM 9380 C C . PHE C 1 363 ? -55.940 17.186 -120.981 1.00 54.08 ? 425 PHE B C 1 +ATOM 9381 O O . PHE C 1 363 ? -54.856 17.574 -120.532 1.00 47.53 ? 425 PHE B O 1 +ATOM 9382 C CB . PHE C 1 363 ? -56.473 16.944 -123.416 1.00 54.87 ? 425 PHE B CB 1 +ATOM 9383 C CG . PHE C 1 363 ? -55.056 16.625 -123.782 1.00 51.31 ? 425 PHE B CG 1 +ATOM 9384 C CD1 . PHE C 1 363 ? -54.300 17.531 -124.501 1.00 51.28 ? 425 PHE B CD1 1 +ATOM 9385 C CD2 . PHE C 1 363 ? -54.481 15.424 -123.409 1.00 47.84 ? 425 PHE B CD2 1 +ATOM 9386 C CE1 . PHE C 1 363 ? -52.998 17.248 -124.841 1.00 50.98 ? 425 PHE B CE1 1 +ATOM 9387 C CE2 . PHE C 1 363 ? -53.179 15.136 -123.745 1.00 48.39 ? 425 PHE B CE2 1 +ATOM 9388 C CZ . PHE C 1 363 ? -52.435 16.050 -124.463 1.00 47.97 ? 425 PHE B CZ 1 +ATOM 9389 N N . LEU C 1 364 ? -56.610 16.163 -120.461 1.00 55.31 ? 426 LEU B N 1 +ATOM 9390 C CA . LEU C 1 364 ? -56.148 15.438 -119.285 1.00 57.00 ? 426 LEU B CA 1 +ATOM 9391 C C . LEU C 1 364 ? -55.475 14.134 -119.691 1.00 56.67 ? 426 LEU B C 1 +ATOM 9392 O O . LEU C 1 364 ? -55.917 13.454 -120.623 1.00 61.16 ? 426 LEU B O 1 +ATOM 9393 C CB . LEU C 1 364 ? -57.309 15.136 -118.335 1.00 57.75 ? 426 LEU B CB 1 +ATOM 9394 C CG . LEU C 1 364 ? -58.270 16.283 -118.035 1.00 55.78 ? 426 LEU B CG 1 +ATOM 9395 C CD1 . LEU C 1 364 ? -59.251 15.889 -116.943 1.00 48.21 ? 426 LEU B CD1 1 +ATOM 9396 C CD2 . LEU C 1 364 ? -57.492 17.528 -117.646 1.00 55.06 ? 426 LEU B CD2 1 +ATOM 9397 N N . ILE C 1 365 ? -54.415 13.782 -118.976 1.00 50.22 ? 427 ILE B N 1 +ATOM 9398 C CA . ILE C 1 365 ? -53.685 12.550 -119.231 1.00 45.12 ? 427 ILE B CA 1 +ATOM 9399 C C . ILE C 1 365 ? -54.220 11.473 -118.304 1.00 45.44 ? 427 ILE B C 1 +ATOM 9400 O O . ILE C 1 365 ? -54.289 11.668 -117.086 1.00 48.61 ? 427 ILE B O 1 +ATOM 9401 C CB . ILE C 1 365 ? -52.178 12.750 -119.021 1.00 42.68 ? 427 ILE B CB 1 +ATOM 9402 C CG1 . ILE C 1 365 ? -51.779 14.172 -119.395 1.00 43.57 ? 427 ILE B CG1 1 +ATOM 9403 C CG2 . ILE C 1 365 ? -51.400 11.753 -119.853 1.00 42.86 ? 427 ILE B CG2 1 +ATOM 9404 C CD1 . ILE C 1 365 ? -50.336 14.465 -119.114 1.00 45.54 ? 427 ILE B CD1 1 +ATOM 9405 N N . HIS C 1 366 ? -54.582 10.328 -118.875 1.00 39.78 ? 428 HIS B N 1 +ATOM 9406 C CA . HIS C 1 366 ? -55.107 9.210 -118.100 1.00 38.83 ? 428 HIS B CA 1 +ATOM 9407 C C . HIS C 1 366 ? -53.978 8.199 -117.931 1.00 38.53 ? 428 HIS B C 1 +ATOM 9408 O O . HIS C 1 366 ? -53.854 7.230 -118.677 1.00 46.93 ? 428 HIS B O 1 +ATOM 9409 C CB . HIS C 1 366 ? -56.328 8.607 -118.787 1.00 43.03 ? 428 HIS B CB 1 +ATOM 9410 C CG . HIS C 1 366 ? -57.374 9.610 -119.172 1.00 43.89 ? 428 HIS B CG 1 +ATOM 9411 N ND1 . HIS C 1 366 ? -58.378 9.328 -120.075 1.00 43.46 ? 428 HIS B ND1 1 +ATOM 9412 C CD2 . HIS C 1 366 ? -57.588 10.883 -118.760 1.00 43.82 ? 428 HIS B CD2 1 +ATOM 9413 C CE1 . HIS C 1 366 ? -59.157 10.385 -120.210 1.00 45.38 ? 428 HIS B CE1 1 +ATOM 9414 N NE2 . HIS C 1 366 ? -58.701 11.342 -119.422 1.00 45.86 ? 428 HIS B NE2 1 +ATOM 9415 N N . LEU C 1 367 ? -53.135 8.442 -116.927 1.00 38.00 ? 429 LEU B N 1 +ATOM 9416 C CA . LEU C 1 367 ? -51.860 7.730 -116.827 1.00 43.66 ? 429 LEU B CA 1 +ATOM 9417 C C . LEU C 1 367 ? -52.004 6.307 -116.294 1.00 46.50 ? 429 LEU B C 1 +ATOM 9418 O O . LEU C 1 367 ? -51.722 5.335 -117.002 1.00 51.70 ? 429 LEU B O 1 +ATOM 9419 C CB . LEU C 1 367 ? -50.880 8.524 -115.962 1.00 47.92 ? 429 LEU B CB 1 +ATOM 9420 C CG . LEU C 1 367 ? -50.124 9.611 -116.719 1.00 47.27 ? 429 LEU B CG 1 +ATOM 9421 C CD1 . LEU C 1 367 ? -49.068 10.256 -115.831 1.00 50.58 ? 429 LEU B CD1 1 +ATOM 9422 C CD2 . LEU C 1 367 ? -49.499 9.029 -117.976 1.00 46.13 ? 429 LEU B CD2 1 +ATOM 9423 N N . ASP C 1 368 ? -52.412 6.162 -115.038 1.00 42.95 ? 430 ASP B N 1 +ATOM 9424 C CA . ASP C 1 368 ? -52.378 4.866 -114.362 1.00 53.38 ? 430 ASP B CA 1 +ATOM 9425 C C . ASP C 1 368 ? -53.782 4.273 -114.347 1.00 48.47 ? 430 ASP B C 1 +ATOM 9426 O O . ASP C 1 368 ? -54.607 4.617 -113.497 1.00 46.49 ? 430 ASP B O 1 +ATOM 9427 C CB . ASP C 1 368 ? -51.814 5.008 -112.951 1.00 74.80 ? 430 ASP B CB 1 +ATOM 9428 C CG . ASP C 1 368 ? -50.300 5.237 -112.937 1.00 84.53 ? 430 ASP B CG 1 +ATOM 9429 O OD1 . ASP C 1 368 ? -49.560 4.352 -113.423 1.00 83.29 ? 430 ASP B OD1 1 +ATOM 9430 O OD2 . ASP C 1 368 ? -49.848 6.290 -112.426 1.00 110.10 ? 430 ASP B OD2 1 +ATOM 9431 N N . ASN C 1 369 ? -54.040 3.354 -115.277 1.00 43.89 ? 431 ASN B N 1 +ATOM 9432 C CA . ASN C 1 369 ? -55.328 2.684 -115.391 1.00 38.00 ? 431 ASN B CA 1 +ATOM 9433 C C . ASN C 1 369 ? -55.249 1.231 -114.963 1.00 39.62 ? 431 ASN B C 1 +ATOM 9434 O O . ASN C 1 369 ? -56.169 0.458 -115.250 1.00 38.00 ? 431 ASN B O 1 +ATOM 9435 C CB . ASN C 1 369 ? -55.847 2.760 -116.824 1.00 38.00 ? 431 ASN B CB 1 +ATOM 9436 C CG . ASN C 1 369 ? -55.539 4.074 -117.483 1.00 39.85 ? 431 ASN B CG 1 +ATOM 9437 O OD1 . ASN C 1 369 ? -56.104 5.106 -117.123 1.00 39.28 ? 431 ASN B OD1 1 +ATOM 9438 N ND2 . ASN C 1 369 ? -54.640 4.048 -118.465 1.00 39.31 ? 431 ASN B ND2 1 +ATOM 9439 N N . ALA C 1 370 ? -54.170 0.841 -114.283 1.00 45.21 ? 432 ALA B N 1 +ATOM 9440 C CA . ALA C 1 370 ? -53.915 -0.561 -113.981 1.00 49.25 ? 432 ALA B CA 1 +ATOM 9441 C C . ALA C 1 370 ? -54.949 -1.173 -113.051 1.00 38.33 ? 432 ALA B C 1 +ATOM 9442 O O . ALA C 1 370 ? -54.890 -2.381 -112.802 1.00 38.00 ? 432 ALA B O 1 +ATOM 9443 C CB . ALA C 1 370 ? -52.522 -0.719 -113.372 1.00 50.93 ? 432 ALA B CB 1 +ATOM 9444 N N . ARG C 1 371 ? -55.881 -0.385 -112.528 1.00 38.00 ? 433 ARG B N 1 +ATOM 9445 C CA . ARG C 1 371 ? -56.852 -0.895 -111.574 1.00 38.00 ? 433 ARG B CA 1 +ATOM 9446 C C . ARG C 1 371 ? -58.185 -1.252 -112.203 1.00 38.00 ? 433 ARG B C 1 +ATOM 9447 O O . ARG C 1 371 ? -58.899 -2.107 -111.671 1.00 39.10 ? 433 ARG B O 1 +ATOM 9448 C CB . ARG C 1 371 ? -57.062 0.124 -110.454 1.00 38.00 ? 433 ARG B CB 1 +ATOM 9449 C CG . ARG C 1 371 ? -55.811 0.346 -109.647 1.00 38.00 ? 433 ARG B CG 1 +ATOM 9450 C CD . ARG C 1 371 ? -56.131 0.451 -108.190 1.00 38.00 ? 433 ARG B CD 1 +ATOM 9451 N NE . ARG C 1 371 ? -54.977 0.877 -107.416 1.00 38.00 ? 433 ARG B NE 1 +ATOM 9452 C CZ . ARG C 1 371 ? -54.682 0.390 -106.219 1.00 38.36 ? 433 ARG B CZ 1 +ATOM 9453 N NH1 . ARG C 1 371 ? -55.451 -0.546 -105.683 1.00 38.00 ? 433 ARG B NH1 1 +ATOM 9454 N NH2 . ARG C 1 371 ? -53.616 0.823 -105.563 1.00 43.46 ? 433 ARG B NH2 1 +ATOM 9455 N N . GLY C 1 372 ? -58.538 -0.628 -113.319 1.00 38.00 ? 434 GLY B N 1 +ATOM 9456 C CA . GLY C 1 372 ? -59.766 -0.953 -114.026 1.00 38.00 ? 434 GLY B CA 1 +ATOM 9457 C C . GLY C 1 372 ? -59.822 -2.385 -114.517 1.00 38.00 ? 434 GLY B C 1 +ATOM 9458 O O . GLY C 1 372 ? -58.850 -3.128 -114.362 1.00 38.00 ? 434 GLY B O 1 +ATOM 9459 N N . PHE C 1 373 ? -60.954 -2.793 -115.091 1.00 38.00 ? 435 PHE B N 1 +ATOM 9460 C CA . PHE C 1 373 ? -61.123 -4.147 -115.623 1.00 38.19 ? 435 PHE B CA 1 +ATOM 9461 C C . PHE C 1 373 ? -60.857 -5.199 -114.554 1.00 42.40 ? 435 PHE B C 1 +ATOM 9462 O O . PHE C 1 373 ? -60.050 -6.110 -114.739 1.00 44.57 ? 435 PHE B O 1 +ATOM 9463 C CB . PHE C 1 373 ? -60.226 -4.357 -116.837 1.00 38.00 ? 435 PHE B CB 1 +ATOM 9464 C CG . PHE C 1 373 ? -60.746 -3.696 -118.051 1.00 38.00 ? 435 PHE B CG 1 +ATOM 9465 C CD1 . PHE C 1 373 ? -62.038 -3.933 -118.470 1.00 38.00 ? 435 PHE B CD1 1 +ATOM 9466 C CD2 . PHE C 1 373 ? -59.968 -2.799 -118.750 1.00 38.00 ? 435 PHE B CD2 1 +ATOM 9467 C CE1 . PHE C 1 373 ? -62.537 -3.312 -119.583 1.00 38.05 ? 435 PHE B CE1 1 +ATOM 9468 C CE2 . PHE C 1 373 ? -60.464 -2.170 -119.867 1.00 38.00 ? 435 PHE B CE2 1 +ATOM 9469 C CZ . PHE C 1 373 ? -61.750 -2.425 -120.284 1.00 38.00 ? 435 PHE B CZ 1 +ATOM 9470 N N . GLY C 1 374 ? -61.531 -5.055 -113.418 1.00 42.62 ? 436 GLY B N 1 +ATOM 9471 C CA . GLY C 1 374 ? -61.409 -6.031 -112.357 1.00 47.35 ? 436 GLY B CA 1 +ATOM 9472 C C . GLY C 1 374 ? -62.736 -6.653 -111.976 1.00 48.14 ? 436 GLY B C 1 +ATOM 9473 O O . GLY C 1 374 ? -62.777 -7.744 -111.405 1.00 48.51 ? 436 GLY B O 1 +ATOM 9474 N N . ARG C 1 375 ? -63.833 -5.988 -112.316 1.00 45.57 ? 437 ARG B N 1 +ATOM 9475 C CA . ARG C 1 375 ? -65.172 -6.475 -111.998 1.00 52.60 ? 437 ARG B CA 1 +ATOM 9476 C C . ARG C 1 375 ? -65.952 -6.478 -113.307 1.00 55.08 ? 437 ARG B C 1 +ATOM 9477 O O . ARG C 1 375 ? -66.377 -5.425 -113.790 1.00 55.51 ? 437 ARG B O 1 +ATOM 9478 C CB . ARG C 1 375 ? -65.856 -5.609 -110.935 1.00 65.12 ? 437 ARG B CB 1 +ATOM 9479 C CG . ARG C 1 375 ? -65.217 -5.629 -109.538 1.00 60.61 ? 437 ARG B CG 1 +ATOM 9480 C CD . ARG C 1 375 ? -65.433 -6.961 -108.814 1.00 73.06 ? 437 ARG B CD 1 +ATOM 9481 N NE . ARG C 1 375 ? -66.847 -7.287 -108.605 1.00 81.32 ? 437 ARG B NE 1 +ATOM 9482 C CZ . ARG C 1 375 ? -67.559 -6.919 -107.541 1.00 76.45 ? 437 ARG B CZ 1 +ATOM 9483 N NH1 . ARG C 1 375 ? -66.998 -6.208 -106.572 1.00 72.70 ? 437 ARG B NH1 1 +ATOM 9484 N NH2 . ARG C 1 375 ? -68.837 -7.267 -107.442 1.00 71.17 ? 437 ARG B NH2 1 +ATOM 9485 N N . HIS C 1 376 ? -66.090 -7.653 -113.912 1.00 55.44 ? 438 HIS B N 1 +ATOM 9486 C CA . HIS C 1 376 ? -66.907 -7.747 -115.112 1.00 57.04 ? 438 HIS B CA 1 +ATOM 9487 C C . HIS C 1 376 ? -68.384 -7.916 -114.793 1.00 58.64 ? 438 HIS B C 1 +ATOM 9488 O O . HIS C 1 376 ? -69.228 -7.702 -115.671 1.00 57.20 ? 438 HIS B O 1 +ATOM 9489 C CB . HIS C 1 376 ? -66.438 -8.912 -115.981 1.00 57.44 ? 438 HIS B CB 1 +ATOM 9490 C CG . HIS C 1 376 ? -66.543 -10.244 -115.309 1.00 52.47 ? 438 HIS B CG 1 +ATOM 9491 N ND1 . HIS C 1 376 ? -67.751 -10.853 -115.046 1.00 48.54 ? 438 HIS B ND1 1 +ATOM 9492 C CD2 . HIS C 1 376 ? -65.589 -11.093 -114.860 1.00 53.95 ? 438 HIS B CD2 1 +ATOM 9493 C CE1 . HIS C 1 376 ? -67.537 -12.014 -114.455 1.00 55.77 ? 438 HIS B CE1 1 +ATOM 9494 N NE2 . HIS C 1 376 ? -66.234 -12.184 -114.331 1.00 57.48 ? 438 HIS B NE2 1 +ATOM 9495 N N . SER C 1 377 ? -68.713 -8.282 -113.556 1.00 57.05 ? 439 SER B N 1 +ATOM 9496 C CA . SER C 1 377 ? -70.091 -8.491 -113.147 1.00 52.52 ? 439 SER B CA 1 +ATOM 9497 C C . SER C 1 377 ? -70.673 -7.311 -112.383 1.00 47.60 ? 439 SER B C 1 +ATOM 9498 O O . SER C 1 377 ? -71.872 -7.317 -112.092 1.00 54.56 ? 439 SER B O 1 +ATOM 9499 C CB . SER C 1 377 ? -70.193 -9.761 -112.294 1.00 52.90 ? 439 SER B CB 1 +ATOM 9500 O OG . SER C 1 377 ? -71.498 -9.922 -111.774 1.00 65.85 ? 439 SER B OG 1 +ATOM 9501 N N . HIS C 1 378 ? -69.870 -6.303 -112.068 1.00 41.64 ? 440 HIS B N 1 +ATOM 9502 C CA . HIS C 1 378 ? -70.311 -5.172 -111.267 1.00 47.79 ? 440 HIS B CA 1 +ATOM 9503 C C . HIS C 1 378 ? -70.015 -3.879 -112.011 1.00 48.03 ? 440 HIS B C 1 +ATOM 9504 O O . HIS C 1 378 ? -68.981 -3.761 -112.673 1.00 52.45 ? 440 HIS B O 1 +ATOM 9505 C CB . HIS C 1 378 ? -69.605 -5.192 -109.904 1.00 56.25 ? 440 HIS B CB 1 +ATOM 9506 C CG . HIS C 1 378 ? -69.996 -4.074 -108.990 1.00 56.05 ? 440 HIS B CG 1 +ATOM 9507 N ND1 . HIS C 1 378 ? -71.295 -3.869 -108.576 1.00 54.05 ? 440 HIS B ND1 1 +ATOM 9508 C CD2 . HIS C 1 378 ? -69.253 -3.110 -108.394 1.00 50.79 ? 440 HIS B CD2 1 +ATOM 9509 C CE1 . HIS C 1 378 ? -71.337 -2.823 -107.771 1.00 56.12 ? 440 HIS B CE1 1 +ATOM 9510 N NE2 . HIS C 1 378 ? -70.112 -2.343 -107.646 1.00 56.00 ? 440 HIS B NE2 1 +ATOM 9511 N N . ASP C 1 379 ? -70.934 -2.919 -111.927 1.00 47.12 ? 441 ASP B N 1 +ATOM 9512 C CA . ASP C 1 379 ? -70.734 -1.591 -112.500 1.00 46.36 ? 441 ASP B CA 1 +ATOM 9513 C C . ASP C 1 379 ? -70.781 -0.568 -111.376 1.00 47.46 ? 441 ASP B C 1 +ATOM 9514 O O . ASP C 1 379 ? -71.799 -0.450 -110.685 1.00 45.77 ? 441 ASP B O 1 +ATOM 9515 C CB . ASP C 1 379 ? -71.791 -1.274 -113.557 1.00 47.36 ? 441 ASP B CB 1 +ATOM 9516 C CG . ASP C 1 379 ? -71.844 -2.311 -114.658 1.00 49.46 ? 441 ASP B CG 1 +ATOM 9517 O OD1 . ASP C 1 379 ? -70.861 -3.064 -114.830 1.00 52.22 ? 441 ASP B OD1 1 +ATOM 9518 O OD2 . ASP C 1 379 ? -72.872 -2.364 -115.362 1.00 47.47 ? 441 ASP B OD2 1 +ATOM 9519 N N . GLU C 1 380 ? -69.686 0.170 -111.191 1.00 50.75 ? 442 GLU B N 1 +ATOM 9520 C CA . GLU C 1 380 ? -69.587 1.139 -110.099 1.00 49.62 ? 442 GLU B CA 1 +ATOM 9521 C C . GLU C 1 380 ? -70.051 2.492 -110.615 1.00 43.08 ? 442 GLU B C 1 +ATOM 9522 O O . GLU C 1 380 ? -69.285 3.228 -111.243 1.00 39.22 ? 442 GLU B O 1 +ATOM 9523 C CB . GLU C 1 380 ? -68.163 1.212 -109.565 1.00 57.29 ? 442 GLU B CB 1 +ATOM 9524 C CG . GLU C 1 380 ? -68.044 2.002 -108.270 1.00 63.74 ? 442 GLU B CG 1 +ATOM 9525 C CD . GLU C 1 380 ? -68.885 1.419 -107.139 1.00 65.60 ? 442 GLU B CD 1 +ATOM 9526 O OE1 . GLU C 1 380 ? -69.824 2.104 -106.676 1.00 68.11 ? 442 GLU B OE1 1 +ATOM 9527 O OE2 . GLU C 1 380 ? -68.625 0.262 -106.735 1.00 57.87 ? 442 GLU B OE2 1 +ATOM 9528 N N . ILE C 1 381 ? -71.299 2.843 -110.303 1.00 43.16 ? 443 ILE B N 1 +ATOM 9529 C CA . ILE C 1 381 ? -71.885 4.057 -110.854 1.00 45.33 ? 443 ILE B CA 1 +ATOM 9530 C C . ILE C 1 381 ? -71.366 5.312 -110.172 1.00 46.35 ? 443 ILE B C 1 +ATOM 9531 O O . ILE C 1 381 ? -71.519 6.410 -110.722 1.00 44.29 ? 443 ILE B O 1 +ATOM 9532 C CB . ILE C 1 381 ? -73.419 4.030 -110.774 1.00 41.29 ? 443 ILE B CB 1 +ATOM 9533 C CG1 . ILE C 1 381 ? -73.938 2.588 -110.711 1.00 40.72 ? 443 ILE B CG1 1 +ATOM 9534 C CG2 . ILE C 1 381 ? -74.013 4.776 -111.963 1.00 38.00 ? 443 ILE B CG2 1 +ATOM 9535 C CD1 . ILE C 1 381 ? -74.175 2.066 -109.292 1.00 41.28 ? 443 ILE B CD1 1 +ATOM 9536 N N . SER C 1 382 ? -70.765 5.187 -108.986 1.00 44.28 ? 444 SER B N 1 +ATOM 9537 C CA . SER C 1 382 ? -70.196 6.359 -108.334 1.00 45.99 ? 444 SER B CA 1 +ATOM 9538 C C . SER C 1 382 ? -69.080 6.973 -109.163 1.00 47.22 ? 444 SER B C 1 +ATOM 9539 O O . SER C 1 382 ? -68.789 8.164 -109.012 1.00 48.20 ? 444 SER B O 1 +ATOM 9540 C CB . SER C 1 382 ? -69.679 6.001 -106.940 1.00 41.60 ? 444 SER B CB 1 +ATOM 9541 O OG . SER C 1 382 ? -68.738 4.948 -107.005 1.00 42.98 ? 444 SER B OG 1 +ATOM 9542 N N . ILE C 1 383 ? -68.453 6.187 -110.039 1.00 47.51 ? 445 ILE B N 1 +ATOM 9543 C CA . ILE C 1 383 ? -67.446 6.742 -110.933 1.00 42.63 ? 445 ILE B CA 1 +ATOM 9544 C C . ILE C 1 383 ? -68.084 7.758 -111.863 1.00 43.39 ? 445 ILE B C 1 +ATOM 9545 O O . ILE C 1 383 ? -67.487 8.792 -112.186 1.00 42.35 ? 445 ILE B O 1 +ATOM 9546 C CB . ILE C 1 383 ? -66.763 5.610 -111.717 1.00 40.99 ? 445 ILE B CB 1 +ATOM 9547 C CG1 . ILE C 1 383 ? -66.349 4.498 -110.755 1.00 42.99 ? 445 ILE B CG1 1 +ATOM 9548 C CG2 . ILE C 1 383 ? -65.552 6.148 -112.448 1.00 43.41 ? 445 ILE B CG2 1 +ATOM 9549 C CD1 . ILE C 1 383 ? -65.839 3.257 -111.427 1.00 40.95 ? 445 ILE B CD1 1 +ATOM 9550 N N . LEU C 1 384 ? -69.324 7.496 -112.274 1.00 48.58 ? 446 LEU B N 1 +ATOM 9551 C CA . LEU C 1 384 ? -70.085 8.344 -113.181 1.00 52.25 ? 446 LEU B CA 1 +ATOM 9552 C C . LEU C 1 384 ? -70.684 9.565 -112.492 1.00 49.94 ? 446 LEU B C 1 +ATOM 9553 O O . LEU C 1 384 ? -71.433 10.313 -113.131 1.00 47.73 ? 446 LEU B O 1 +ATOM 9554 C CB . LEU C 1 384 ? -71.197 7.521 -113.844 1.00 48.10 ? 446 LEU B CB 1 +ATOM 9555 C CG . LEU C 1 384 ? -71.335 7.540 -115.370 1.00 42.68 ? 446 LEU B CG 1 +ATOM 9556 C CD1 . LEU C 1 384 ? -72.312 8.607 -115.822 1.00 46.80 ? 446 LEU B CD1 1 +ATOM 9557 C CD2 . LEU C 1 384 ? -69.990 7.749 -116.030 1.00 41.06 ? 446 LEU B CD2 1 +ATOM 9558 N N . SER C 1 385 ? -70.356 9.786 -111.222 1.00 50.48 ? 447 SER B N 1 +ATOM 9559 C CA . SER C 1 385 ? -70.906 10.924 -110.489 1.00 52.72 ? 447 SER B CA 1 +ATOM 9560 C C . SER C 1 385 ? -70.703 12.273 -111.173 1.00 53.20 ? 447 SER B C 1 +ATOM 9561 O O . SER C 1 385 ? -71.623 13.104 -111.099 1.00 60.26 ? 447 SER B O 1 +ATOM 9562 C CB . SER C 1 385 ? -70.321 10.951 -109.070 1.00 49.75 ? 447 SER B CB 1 +ATOM 9563 O OG . SER C 1 385 ? -70.858 9.895 -108.292 1.00 50.32 ? 447 SER B OG 1 +ATOM 9564 N N . PRO C 1 386 ? -69.568 12.575 -111.822 1.00 45.24 ? 448 PRO B N 1 +ATOM 9565 C CA . PRO C 1 386 ? -69.480 13.873 -112.515 1.00 42.29 ? 448 PRO B CA 1 +ATOM 9566 C C . PRO C 1 386 ? -70.569 14.068 -113.556 1.00 44.95 ? 448 PRO B C 1 +ATOM 9567 O O . PRO C 1 386 ? -71.233 15.112 -113.570 1.00 45.91 ? 448 PRO B O 1 +ATOM 9568 C CB . PRO C 1 386 ? -68.080 13.834 -113.140 1.00 39.72 ? 448 PRO B CB 1 +ATOM 9569 C CG . PRO C 1 386 ? -67.310 12.950 -112.261 1.00 44.65 ? 448 PRO B CG 1 +ATOM 9570 C CD . PRO C 1 386 ? -68.269 11.879 -111.830 1.00 45.48 ? 448 PRO B CD 1 +ATOM 9571 N N . LEU C 1 387 ? -70.784 13.081 -114.426 1.00 40.93 ? 449 LEU B N 1 +ATOM 9572 C CA . LEU C 1 387 ? -71.844 13.205 -115.417 1.00 41.29 ? 449 LEU B CA 1 +ATOM 9573 C C . LEU C 1 387 ? -73.219 13.137 -114.773 1.00 45.52 ? 449 LEU B C 1 +ATOM 9574 O O . LEU C 1 387 ? -74.152 13.806 -115.234 1.00 50.93 ? 449 LEU B O 1 +ATOM 9575 C CB . LEU C 1 387 ? -71.703 12.120 -116.477 1.00 38.00 ? 449 LEU B CB 1 +ATOM 9576 C CG . LEU C 1 387 ? -72.654 12.230 -117.664 1.00 38.00 ? 449 LEU B CG 1 +ATOM 9577 C CD1 . LEU C 1 387 ? -72.425 13.531 -118.423 1.00 38.00 ? 449 LEU B CD1 1 +ATOM 9578 C CD2 . LEU C 1 387 ? -72.476 11.036 -118.568 1.00 42.85 ? 449 LEU B CD2 1 +ATOM 9579 N N . SER C 1 388 ? -73.364 12.344 -113.709 1.00 47.79 ? 450 SER B N 1 +ATOM 9580 C CA . SER C 1 388 ? -74.659 12.226 -113.050 1.00 49.34 ? 450 SER B CA 1 +ATOM 9581 C C . SER C 1 388 ? -75.100 13.560 -112.464 1.00 52.47 ? 450 SER B C 1 +ATOM 9582 O O . SER C 1 388 ? -76.246 13.984 -112.657 1.00 56.87 ? 450 SER B O 1 +ATOM 9583 C CB . SER C 1 388 ? -74.594 11.165 -111.947 1.00 46.88 ? 450 SER B CB 1 +ATOM 9584 O OG . SER C 1 388 ? -74.155 9.912 -112.442 1.00 46.51 ? 450 SER B OG 1 +ATOM 9585 N N . GLN C 1 389 ? -74.186 14.263 -111.796 1.00 49.31 ? 451 GLN B N 1 +ATOM 9586 C CA . GLN C 1 389 ? -74.532 15.449 -111.025 1.00 49.93 ? 451 GLN B CA 1 +ATOM 9587 C C . GLN C 1 389 ? -74.410 16.731 -111.838 1.00 55.70 ? 451 GLN B C 1 +ATOM 9588 O O . GLN C 1 389 ? -75.289 17.595 -111.758 1.00 64.43 ? 451 GLN B O 1 +ATOM 9589 C CB . GLN C 1 389 ? -73.643 15.532 -109.779 1.00 53.69 ? 451 GLN B CB 1 +ATOM 9590 C CG . GLN C 1 389 ? -73.632 14.242 -108.951 1.00 57.93 ? 451 GLN B CG 1 +ATOM 9591 C CD . GLN C 1 389 ? -72.609 14.254 -107.822 1.00 52.52 ? 451 GLN B CD 1 +ATOM 9592 O OE1 . GLN C 1 389 ? -71.487 14.741 -107.984 1.00 48.02 ? 451 GLN B OE1 1 +ATOM 9593 N NE2 . GLN C 1 389 ? -72.983 13.681 -106.682 1.00 50.39 ? 451 GLN B NE2 1 +ATOM 9594 N N . CYS C 1 390 ? -73.346 16.868 -112.634 1.00 53.95 ? 452 CYS B N 1 +ATOM 9595 C CA . CYS C 1 390 ? -73.185 18.070 -113.448 1.00 55.42 ? 452 CYS B CA 1 +ATOM 9596 C C . CYS C 1 390 ? -74.184 18.104 -114.588 1.00 60.74 ? 452 CYS B C 1 +ATOM 9597 O O . CYS C 1 390 ? -74.677 19.175 -114.961 1.00 65.95 ? 452 CYS B O 1 +ATOM 9598 C CB . CYS C 1 390 ? -71.769 18.145 -113.998 1.00 52.04 ? 452 CYS B CB 1 +ATOM 9599 S SG . CYS C 1 390 ? -70.542 18.162 -112.714 1.00 66.10 ? 452 CYS B SG 1 +ATOM 9600 N N . CYS C 1 391 ? -74.464 16.943 -115.168 1.00 56.80 ? 453 CYS B N 1 +ATOM 9601 C CA . CYS C 1 391 ? -75.404 16.803 -116.269 1.00 57.33 ? 453 CYS B CA 1 +ATOM 9602 C C . CYS C 1 391 ? -75.042 17.755 -117.415 1.00 58.20 ? 453 CYS B C 1 +ATOM 9603 O O . CYS C 1 391 ? -75.730 18.732 -117.714 1.00 57.28 ? 453 CYS B O 1 +ATOM 9604 C CB . CYS C 1 391 ? -76.834 17.019 -115.776 1.00 57.38 ? 453 CYS B CB 1 +ATOM 9605 S SG . CYS C 1 391 ? -78.031 16.718 -117.071 1.00 97.46 ? 453 CYS B SG 1 +ATOM 9606 N N . MET C 1 392 ? -73.907 17.433 -118.032 1.00 54.27 ? 454 MET B N 1 +ATOM 9607 C CA . MET C 1 392 ? -73.455 18.059 -119.268 1.00 54.57 ? 454 MET B CA 1 +ATOM 9608 C C . MET C 1 392 ? -72.321 17.232 -119.854 1.00 47.92 ? 454 MET B C 1 +ATOM 9609 O O . MET C 1 392 ? -71.442 16.776 -119.119 1.00 46.16 ? 454 MET B O 1 +ATOM 9610 C CB . MET C 1 392 ? -73.028 19.510 -119.035 1.00 56.04 ? 454 MET B CB 1 +ATOM 9611 C CG . MET C 1 392 ? -72.148 19.734 -117.835 1.00 55.06 ? 454 MET B CG 1 +ATOM 9612 S SD . MET C 1 392 ? -72.037 21.496 -117.488 1.00 57.55 ? 454 MET B SD 1 +ATOM 9613 C CE . MET C 1 392 ? -71.757 22.151 -119.132 1.00 46.85 ? 454 MET B CE 1 +ATOM 9614 N N . ILE C 1 393 ? -72.365 16.999 -121.166 1.00 47.97 ? 455 ILE B N 1 +ATOM 9615 C CA . ILE C 1 393 ? -71.411 16.150 -121.869 1.00 48.37 ? 455 ILE B CA 1 +ATOM 9616 C C . ILE C 1 393 ? -70.996 16.851 -123.155 1.00 55.99 ? 455 ILE B C 1 +ATOM 9617 O O . ILE C 1 393 ? -71.779 17.595 -123.753 1.00 64.73 ? 455 ILE B O 1 +ATOM 9618 C CB . ILE C 1 393 ? -72.013 14.757 -122.173 1.00 45.59 ? 455 ILE B CB 1 +ATOM 9619 C CG1 . ILE C 1 393 ? -70.989 13.834 -122.819 1.00 49.88 ? 455 ILE B CG1 1 +ATOM 9620 C CG2 . ILE C 1 393 ? -73.200 14.864 -123.098 1.00 46.32 ? 455 ILE B CG2 1 +ATOM 9621 C CD1 . ILE C 1 393 ? -71.567 12.481 -123.176 1.00 46.11 ? 455 ILE B CD1 1 +ATOM 9622 N N . LYS C 1 394 ? -69.756 16.614 -123.586 1.00 58.66 ? 456 LYS B N 1 +ATOM 9623 C CA . LYS C 1 394 ? -69.268 17.241 -124.808 1.00 64.47 ? 456 LYS B CA 1 +ATOM 9624 C C . LYS C 1 394 ? -69.970 16.670 -126.038 1.00 57.15 ? 456 LYS B C 1 +ATOM 9625 O O . LYS C 1 394 ? -70.338 15.492 -126.089 1.00 49.29 ? 456 LYS B O 1 +ATOM 9626 C CB . LYS C 1 394 ? -67.750 17.079 -124.933 1.00 55.66 ? 456 LYS B CB 1 +ATOM 9627 C CG . LYS C 1 394 ? -67.013 17.422 -123.649 1.00 65.07 ? 456 LYS B CG 1 +ATOM 9628 C CD . LYS C 1 394 ? -65.579 17.931 -123.872 1.00 75.68 ? 456 LYS B CD 1 +ATOM 9629 C CE . LYS C 1 394 ? -64.672 16.910 -124.538 1.00 69.94 ? 456 LYS B CE 1 +ATOM 9630 N NZ . LYS C 1 394 ? -63.235 17.321 -124.464 1.00 50.56 ? 456 LYS B NZ 1 +ATOM 9631 N N . LYS C 1 395 ? -70.171 17.538 -127.033 1.00 58.76 ? 457 LYS B N 1 +ATOM 9632 C CA . LYS C 1 395 ? -70.845 17.127 -128.261 1.00 55.18 ? 457 LYS B CA 1 +ATOM 9633 C C . LYS C 1 395 ? -70.090 15.993 -128.943 1.00 52.43 ? 457 LYS B C 1 +ATOM 9634 O O . LYS C 1 395 ? -70.672 14.951 -129.265 1.00 50.31 ? 457 LYS B O 1 +ATOM 9635 C CB . LYS C 1 395 ? -70.990 18.323 -129.203 1.00 66.05 ? 457 LYS B CB 1 +ATOM 9636 C CG . LYS C 1 395 ? -71.738 18.025 -130.499 1.00 68.68 ? 457 LYS B CG 1 +ATOM 9637 C CD . LYS C 1 395 ? -73.242 18.045 -130.305 1.00 62.63 ? 457 LYS B CD 1 +ATOM 9638 C CE . LYS C 1 395 ? -73.956 18.410 -131.597 1.00 62.05 ? 457 LYS B CE 1 +ATOM 9639 N NZ . LYS C 1 395 ? -75.424 18.535 -131.387 1.00 66.12 ? 457 LYS B NZ 1 +ATOM 9640 N N . LYS C 1 396 ? -68.784 16.182 -129.163 1.00 46.90 ? 458 LYS B N 1 +ATOM 9641 C CA . LYS C 1 396 ? -67.971 15.150 -129.796 1.00 40.97 ? 458 LYS B CA 1 +ATOM 9642 C C . LYS C 1 396 ? -68.024 13.846 -129.011 1.00 43.34 ? 458 LYS B C 1 +ATOM 9643 O O . LYS C 1 396 ? -68.176 12.768 -129.595 1.00 39.85 ? 458 LYS B O 1 +ATOM 9644 C CB . LYS C 1 396 ? -66.529 15.638 -129.933 1.00 38.00 ? 458 LYS B CB 1 +ATOM 9645 C CG . LYS C 1 396 ? -65.545 14.549 -130.313 1.00 46.34 ? 458 LYS B CG 1 +ATOM 9646 C CD . LYS C 1 396 ? -64.144 15.104 -130.525 1.00 54.44 ? 458 LYS B CD 1 +ATOM 9647 C CE . LYS C 1 396 ? -63.123 13.979 -130.635 1.00 62.21 ? 458 LYS B CE 1 +ATOM 9648 N NZ . LYS C 1 396 ? -62.592 13.809 -132.015 1.00 71.13 ? 458 LYS B NZ 1 +ATOM 9649 N N . THR C 1 397 ? -67.916 13.928 -127.683 1.00 50.86 ? 459 THR B N 1 +ATOM 9650 C CA . THR C 1 397 ? -67.914 12.721 -126.861 1.00 49.76 ? 459 THR B CA 1 +ATOM 9651 C C . THR C 1 397 ? -69.226 11.960 -127.001 1.00 48.91 ? 459 THR B C 1 +ATOM 9652 O O . THR C 1 397 ? -69.234 10.726 -127.074 1.00 44.78 ? 459 THR B O 1 +ATOM 9653 C CB . THR C 1 397 ? -67.676 13.084 -125.393 1.00 46.56 ? 459 THR B CB 1 +ATOM 9654 O OG1 . THR C 1 397 ? -66.495 13.884 -125.271 1.00 44.88 ? 459 THR B OG1 1 +ATOM 9655 C CG2 . THR C 1 397 ? -67.504 11.823 -124.562 1.00 38.00 ? 459 THR B CG2 1 +ATOM 9656 N N . LEU C 1 398 ? -70.346 12.685 -127.057 1.00 54.42 ? 460 LEU B N 1 +ATOM 9657 C CA . LEU C 1 398 ? -71.649 12.033 -127.128 1.00 52.35 ? 460 LEU B CA 1 +ATOM 9658 C C . LEU C 1 398 ? -71.847 11.327 -128.461 1.00 48.13 ? 460 LEU B C 1 +ATOM 9659 O O . LEU C 1 398 ? -72.437 10.242 -128.513 1.00 46.17 ? 460 LEU B O 1 +ATOM 9660 C CB . LEU C 1 398 ? -72.757 13.061 -126.898 1.00 54.51 ? 460 LEU B CB 1 +ATOM 9661 C CG . LEU C 1 398 ? -74.195 12.540 -126.942 1.00 54.16 ? 460 LEU B CG 1 +ATOM 9662 C CD1 . LEU C 1 398 ? -74.372 11.331 -126.033 1.00 49.45 ? 460 LEU B CD1 1 +ATOM 9663 C CD2 . LEU C 1 398 ? -75.172 13.649 -126.573 1.00 54.62 ? 460 LEU B CD2 1 +ATOM 9664 N N . LEU C 1 399 ? -71.358 11.924 -129.546 1.00 47.59 ? 461 LEU B N 1 +ATOM 9665 C CA . LEU C 1 399 ? -71.515 11.313 -130.860 1.00 48.44 ? 461 LEU B CA 1 +ATOM 9666 C C . LEU C 1 399 ? -70.729 10.010 -130.954 1.00 48.86 ? 461 LEU B C 1 +ATOM 9667 O O . LEU C 1 399 ? -71.210 9.029 -131.537 1.00 41.45 ? 461 LEU B O 1 +ATOM 9668 C CB . LEU C 1 399 ? -71.076 12.301 -131.940 1.00 43.57 ? 461 LEU B CB 1 +ATOM 9669 C CG . LEU C 1 399 ? -71.829 13.632 -131.943 1.00 38.00 ? 461 LEU B CG 1 +ATOM 9670 C CD1 . LEU C 1 399 ? -71.307 14.533 -133.035 1.00 38.00 ? 461 LEU B CD1 1 +ATOM 9671 C CD2 . LEU C 1 399 ? -73.312 13.402 -132.109 1.00 38.00 ? 461 LEU B CD2 1 +ATOM 9672 N N . HIS C 1 400 ? -69.512 9.985 -130.395 1.00 48.92 ? 462 HIS B N 1 +ATOM 9673 C CA . HIS C 1 400 ? -68.720 8.757 -130.394 1.00 46.93 ? 462 HIS B CA 1 +ATOM 9674 C C . HIS C 1 400 ? -69.366 7.679 -129.529 1.00 48.21 ? 462 HIS B C 1 +ATOM 9675 O O . HIS C 1 400 ? -69.330 6.493 -129.879 1.00 43.81 ? 462 HIS B O 1 +ATOM 9676 C CB . HIS C 1 400 ? -67.296 9.040 -129.910 1.00 41.07 ? 462 HIS B CB 1 +ATOM 9677 C CG . HIS C 1 400 ? -66.456 9.807 -130.884 1.00 41.15 ? 462 HIS B CG 1 +ATOM 9678 N ND1 . HIS C 1 400 ? -65.587 9.194 -131.759 1.00 41.92 ? 462 HIS B ND1 1 +ATOM 9679 C CD2 . HIS C 1 400 ? -66.330 11.138 -131.102 1.00 47.10 ? 462 HIS B CD2 1 +ATOM 9680 C CE1 . HIS C 1 400 ? -64.975 10.111 -132.488 1.00 47.16 ? 462 HIS B CE1 1 +ATOM 9681 N NE2 . HIS C 1 400 ? -65.408 11.299 -132.108 1.00 49.19 ? 462 HIS B NE2 1 +ATOM 9682 N N . LEU C 1 401 ? -69.978 8.070 -128.408 1.00 52.21 ? 463 LEU B N 1 +ATOM 9683 C CA . LEU C 1 401 ? -70.642 7.091 -127.550 1.00 51.30 ? 463 LEU B CA 1 +ATOM 9684 C C . LEU C 1 401 ? -71.889 6.541 -128.222 1.00 51.85 ? 463 LEU B C 1 +ATOM 9685 O O . LEU C 1 401 ? -72.118 5.325 -128.231 1.00 46.72 ? 463 LEU B O 1 +ATOM 9686 C CB . LEU C 1 401 ? -71.003 7.725 -126.206 1.00 45.30 ? 463 LEU B CB 1 +ATOM 9687 C CG . LEU C 1 401 ? -69.848 8.110 -125.288 1.00 46.72 ? 463 LEU B CG 1 +ATOM 9688 C CD1 . LEU C 1 401 ? -70.367 8.662 -123.977 1.00 46.88 ? 463 LEU B CD1 1 +ATOM 9689 C CD2 . LEU C 1 401 ? -68.967 6.906 -125.050 1.00 47.21 ? 463 LEU B CD2 1 +ATOM 9690 N N . GLN C 1 402 ? -72.705 7.429 -128.800 1.00 50.67 ? 464 GLN B N 1 +ATOM 9691 C CA . GLN C 1 402 ? -73.903 6.986 -129.499 1.00 48.79 ? 464 GLN B CA 1 +ATOM 9692 C C . GLN C 1 402 ? -73.540 6.055 -130.643 1.00 51.55 ? 464 GLN B C 1 +ATOM 9693 O O . GLN C 1 402 ? -74.189 5.021 -130.846 1.00 49.60 ? 464 GLN B O 1 +ATOM 9694 C CB . GLN C 1 402 ? -74.693 8.194 -130.016 1.00 51.27 ? 464 GLN B CB 1 +ATOM 9695 C CG . GLN C 1 402 ? -75.450 8.974 -128.946 1.00 51.52 ? 464 GLN B CG 1 +ATOM 9696 C CD . GLN C 1 402 ? -76.133 10.220 -129.492 1.00 54.84 ? 464 GLN B CD 1 +ATOM 9697 O OE1 . GLN C 1 402 ? -75.935 10.599 -130.646 1.00 54.01 ? 464 GLN B OE1 1 +ATOM 9698 N NE2 . GLN C 1 402 ? -76.945 10.859 -128.660 1.00 60.17 ? 464 GLN B NE2 1 +ATOM 9699 N N . LEU C 1 403 ? -72.484 6.396 -131.385 1.00 50.74 ? 465 LEU B N 1 +ATOM 9700 C CA . LEU C 1 403 ? -72.064 5.562 -132.502 1.00 51.66 ? 465 LEU B CA 1 +ATOM 9701 C C . LEU C 1 403 ? -71.654 4.179 -132.022 1.00 50.53 ? 465 LEU B C 1 +ATOM 9702 O O . LEU C 1 403 ? -71.992 3.169 -132.650 1.00 50.68 ? 465 LEU B O 1 +ATOM 9703 C CB . LEU C 1 403 ? -70.920 6.244 -133.250 1.00 44.60 ? 465 LEU B CB 1 +ATOM 9704 C CG . LEU C 1 403 ? -70.558 5.754 -134.653 1.00 43.68 ? 465 LEU B CG 1 +ATOM 9705 C CD1 . LEU C 1 403 ? -69.784 6.837 -135.364 1.00 45.53 ? 465 LEU B CD1 1 +ATOM 9706 C CD2 . LEU C 1 403 ? -69.744 4.491 -134.625 1.00 38.00 ? 465 LEU B CD2 1 +ATOM 9707 N N . LEU C 1 404 ? -70.920 4.116 -130.912 1.00 50.33 ? 466 LEU B N 1 +ATOM 9708 C CA . LEU C 1 404 ? -70.433 2.853 -130.367 1.00 53.87 ? 466 LEU B CA 1 +ATOM 9709 C C . LEU C 1 404 ? -71.532 1.991 -129.756 1.00 56.41 ? 466 LEU B C 1 +ATOM 9710 O O . LEU C 1 404 ? -71.234 0.888 -129.281 1.00 53.39 ? 466 LEU B O 1 +ATOM 9711 C CB . LEU C 1 404 ? -69.338 3.131 -129.337 1.00 51.55 ? 466 LEU B CB 1 +ATOM 9712 C CG . LEU C 1 404 ? -68.001 3.557 -129.946 1.00 44.84 ? 466 LEU B CG 1 +ATOM 9713 C CD1 . LEU C 1 404 ? -67.125 4.223 -128.915 1.00 44.49 ? 466 LEU B CD1 1 +ATOM 9714 C CD2 . LEU C 1 404 ? -67.299 2.339 -130.527 1.00 46.13 ? 466 LEU B CD2 1 +ATOM 9715 N N . ALA C 1 405 ? -72.784 2.446 -129.760 1.00 57.42 ? 467 ALA B N 1 +ATOM 9716 C CA . ALA C 1 405 ? -73.889 1.628 -129.281 1.00 59.07 ? 467 ALA B CA 1 +ATOM 9717 C C . ALA C 1 405 ? -74.584 0.853 -130.394 1.00 56.26 ? 467 ALA B C 1 +ATOM 9718 O O . ALA C 1 405 ? -75.322 -0.093 -130.098 1.00 51.27 ? 467 ALA B O 1 +ATOM 9719 C CB . ALA C 1 405 ? -74.915 2.503 -128.552 1.00 60.19 ? 467 ALA B CB 1 +ATOM 9720 N N . GLN C 1 406 ? -74.334 1.198 -131.655 1.00 54.34 ? 468 GLN B N 1 +ATOM 9721 C CA . GLN C 1 406 ? -74.973 0.541 -132.789 1.00 56.36 ? 468 GLN B CA 1 +ATOM 9722 C C . GLN C 1 406 ? -74.204 -0.713 -133.179 1.00 56.49 ? 468 GLN B C 1 +ATOM 9723 O O . GLN C 1 406 ? -72.975 -0.760 -133.076 1.00 57.38 ? 468 GLN B O 1 +ATOM 9724 C CB . GLN C 1 406 ? -75.074 1.496 -133.980 1.00 52.13 ? 468 GLN B CB 1 +ATOM 9725 C CG . GLN C 1 406 ? -75.985 2.677 -133.710 1.00 61.34 ? 468 GLN B CG 1 +ATOM 9726 C CD . GLN C 1 406 ? -75.659 3.887 -134.554 1.00 69.16 ? 468 GLN B CD 1 +ATOM 9727 O OE1 . GLN C 1 406 ? -74.907 3.801 -135.527 1.00 64.79 ? 468 GLN B OE1 1 +ATOM 9728 N NE2 . GLN C 1 406 ? -76.214 5.035 -134.175 1.00 69.52 ? 468 GLN B NE2 1 +ATOM 9729 N N . ALA C 1 407 ? -74.944 -1.743 -133.598 1.00 59.04 ? 469 ALA B N 1 +ATOM 9730 C CA . ALA C 1 407 ? -74.343 -3.053 -133.837 1.00 57.72 ? 469 ALA B CA 1 +ATOM 9731 C C . ALA C 1 407 ? -73.262 -3.009 -134.912 1.00 57.13 ? 469 ALA B C 1 +ATOM 9732 O O . ALA C 1 407 ? -72.350 -3.845 -134.904 1.00 55.03 ? 469 ALA B O 1 +ATOM 9733 C CB . ALA C 1 407 ? -75.423 -4.063 -134.217 1.00 68.98 ? 469 ALA B CB 1 +ATOM 9734 N N . ASP C 1 408 ? -73.354 -2.065 -135.856 1.00 61.05 ? 470 ASP B N 1 +ATOM 9735 C CA . ASP C 1 408 ? -72.337 -1.957 -136.901 1.00 58.00 ? 470 ASP B CA 1 +ATOM 9736 C C . ASP C 1 408 ? -70.986 -1.513 -136.343 1.00 49.93 ? 470 ASP B C 1 +ATOM 9737 O O . ASP C 1 408 ? -69.945 -1.806 -136.943 1.00 46.86 ? 470 ASP B O 1 +ATOM 9738 C CB . ASP C 1 408 ? -72.804 -1.006 -138.005 1.00 55.81 ? 470 ASP B CB 1 +ATOM 9739 C CG . ASP C 1 408 ? -74.024 -1.527 -138.752 1.00 50.88 ? 470 ASP B CG 1 +ATOM 9740 O OD1 . ASP C 1 408 ? -73.924 -2.589 -139.402 1.00 41.22 ? 470 ASP B OD1 1 +ATOM 9741 O OD2 . ASP C 1 408 ? -75.084 -0.871 -138.694 1.00 60.91 ? 470 ASP B OD2 1 +ATOM 9742 N N . TYR C 1 409 ? -70.976 -0.796 -135.222 1.00 52.74 ? 471 TYR B N 1 +ATOM 9743 C CA . TYR C 1 409 ? -69.728 -0.382 -134.584 1.00 51.91 ? 471 TYR B CA 1 +ATOM 9744 C C . TYR C 1 409 ? -69.839 -0.489 -133.068 1.00 51.23 ? 471 TYR B C 1 +ATOM 9745 O O . TYR C 1 409 ? -69.522 0.448 -132.335 1.00 47.70 ? 471 TYR B O 1 +ATOM 9746 C CB . TYR C 1 409 ? -69.345 1.046 -134.964 1.00 52.77 ? 471 TYR B CB 1 +ATOM 9747 C CG . TYR C 1 409 ? -69.793 1.501 -136.332 1.00 51.67 ? 471 TYR B CG 1 +ATOM 9748 C CD1 . TYR C 1 409 ? -71.054 2.044 -136.525 1.00 56.17 ? 471 TYR B CD1 1 +ATOM 9749 C CD2 . TYR C 1 409 ? -68.943 1.419 -137.423 1.00 56.96 ? 471 TYR B CD2 1 +ATOM 9750 C CE1 . TYR C 1 409 ? -71.461 2.476 -137.766 1.00 63.19 ? 471 TYR B CE1 1 +ATOM 9751 C CE2 . TYR C 1 409 ? -69.342 1.848 -138.668 1.00 58.21 ? 471 TYR B CE2 1 +ATOM 9752 C CZ . TYR C 1 409 ? -70.602 2.375 -138.834 1.00 64.71 ? 471 TYR B CZ 1 +ATOM 9753 O OH . TYR C 1 409 ? -71.010 2.803 -140.075 1.00 83.79 ? 471 TYR B OH 1 +ATOM 9754 N N . ARG C 1 410 ? -70.280 -1.641 -132.570 1.00 47.95 ? 472 ARG B N 1 +ATOM 9755 C CA . ARG C 1 410 ? -70.482 -1.769 -131.133 1.00 55.25 ? 472 ARG B CA 1 +ATOM 9756 C C . ARG C 1 410 ? -69.153 -1.852 -130.393 1.00 54.66 ? 472 ARG B C 1 +ATOM 9757 O O . ARG C 1 410 ? -68.162 -2.383 -130.900 1.00 51.02 ? 472 ARG B O 1 +ATOM 9758 C CB . ARG C 1 410 ? -71.337 -2.989 -130.798 1.00 60.85 ? 472 ARG B CB 1 +ATOM 9759 C CG . ARG C 1 410 ? -70.720 -4.328 -131.121 1.00 55.81 ? 472 ARG B CG 1 +ATOM 9760 C CD . ARG C 1 410 ? -71.477 -5.422 -130.383 1.00 58.04 ? 472 ARG B CD 1 +ATOM 9761 N NE . ARG C 1 410 ? -72.887 -5.074 -130.200 1.00 62.37 ? 472 ARG B NE 1 +ATOM 9762 C CZ . ARG C 1 410 ? -73.874 -5.444 -131.013 1.00 70.53 ? 472 ARG B CZ 1 +ATOM 9763 N NH1 . ARG C 1 410 ? -73.626 -6.191 -132.086 1.00 70.25 ? 472 ARG B NH1 1 +ATOM 9764 N NH2 . ARG C 1 410 ? -75.120 -5.066 -130.749 1.00 73.31 ? 472 ARG B NH2 1 +ATOM 9765 N N . LEU C 1 411 ? -69.162 -1.337 -129.159 1.00 53.90 ? 473 LEU B N 1 +ATOM 9766 C CA . LEU C 1 411 ? -67.930 -1.128 -128.402 1.00 51.16 ? 473 LEU B CA 1 +ATOM 9767 C C . LEU C 1 411 ? -67.226 -2.437 -128.066 1.00 45.49 ? 473 LEU B C 1 +ATOM 9768 O O . LEU C 1 411 ? -65.993 -2.474 -127.993 1.00 45.27 ? 473 LEU B O 1 +ATOM 9769 C CB . LEU C 1 411 ? -68.234 -0.359 -127.118 1.00 47.28 ? 473 LEU B CB 1 +ATOM 9770 C CG . LEU C 1 411 ? -67.028 0.008 -126.256 1.00 38.27 ? 473 LEU B CG 1 +ATOM 9771 C CD1 . LEU C 1 411 ? -66.056 0.817 -127.078 1.00 38.00 ? 473 LEU B CD1 1 +ATOM 9772 C CD2 . LEU C 1 411 ? -67.455 0.774 -125.022 1.00 43.08 ? 473 LEU B CD2 1 +ATOM 9773 N N . SER C 1 412 ? -67.976 -3.512 -127.824 1.00 45.85 ? 474 SER B N 1 +ATOM 9774 C CA . SER C 1 412 ? -67.313 -4.758 -127.463 1.00 44.23 ? 474 SER B CA 1 +ATOM 9775 C C . SER C 1 412 ? -66.576 -5.345 -128.652 1.00 46.59 ? 474 SER B C 1 +ATOM 9776 O O . SER C 1 412 ? -65.452 -5.835 -128.510 1.00 54.04 ? 474 SER B O 1 +ATOM 9777 C CB . SER C 1 412 ? -68.316 -5.776 -126.925 1.00 52.28 ? 474 SER B CB 1 +ATOM 9778 O OG . SER C 1 412 ? -69.323 -6.049 -127.878 1.00 58.49 ? 474 SER B OG 1 +ATOM 9779 N N . ASP C 1 413 ? -67.182 -5.289 -129.838 1.00 49.19 ? 475 ASP B N 1 +ATOM 9780 C CA . ASP C 1 413 ? -66.566 -5.939 -130.987 1.00 49.88 ? 475 ASP B CA 1 +ATOM 9781 C C . ASP C 1 413 ? -65.336 -5.179 -131.462 1.00 43.82 ? 475 ASP B C 1 +ATOM 9782 O O . ASP C 1 413 ? -64.306 -5.792 -131.764 1.00 47.84 ? 475 ASP B O 1 +ATOM 9783 C CB . ASP C 1 413 ? -67.586 -6.096 -132.114 1.00 50.85 ? 475 ASP B CB 1 +ATOM 9784 C CG . ASP C 1 413 ? -68.585 -7.205 -131.839 1.00 51.13 ? 475 ASP B CG 1 +ATOM 9785 O OD1 . ASP C 1 413 ? -68.267 -8.101 -131.024 1.00 48.41 ? 475 ASP B OD1 1 +ATOM 9786 O OD2 . ASP C 1 413 ? -69.678 -7.192 -132.445 1.00 54.51 ? 475 ASP B OD2 1 +ATOM 9787 N N . VAL C 1 414 ? -65.404 -3.847 -131.497 1.00 40.27 ? 476 VAL B N 1 +ATOM 9788 C CA . VAL C 1 414 ? -64.248 -3.084 -131.953 1.00 40.60 ? 476 VAL B CA 1 +ATOM 9789 C C . VAL C 1 414 ? -63.112 -3.167 -130.941 1.00 42.27 ? 476 VAL B C 1 +ATOM 9790 O O . VAL C 1 414 ? -61.935 -3.089 -131.314 1.00 48.61 ? 476 VAL B O 1 +ATOM 9791 C CB . VAL C 1 414 ? -64.647 -1.628 -132.250 1.00 39.59 ? 476 VAL B CB 1 +ATOM 9792 C CG1 . VAL C 1 414 ? -65.637 -1.583 -133.392 1.00 38.72 ? 476 VAL B CG1 1 +ATOM 9793 C CG2 . VAL C 1 414 ? -65.227 -0.969 -131.015 1.00 51.14 ? 476 VAL B CG2 1 +ATOM 9794 N N . MET C 1 415 ? -63.427 -3.338 -129.656 1.00 39.61 ? 477 MET B N 1 +ATOM 9795 C CA . MET C 1 415 ? -62.370 -3.582 -128.682 1.00 38.00 ? 477 MET B CA 1 +ATOM 9796 C C . MET C 1 415 ? -61.786 -4.975 -128.861 1.00 38.32 ? 477 MET B C 1 +ATOM 9797 O O . MET C 1 415 ? -60.567 -5.136 -128.957 1.00 44.68 ? 477 MET B O 1 +ATOM 9798 C CB . MET C 1 415 ? -62.898 -3.401 -127.258 1.00 41.46 ? 477 MET B CB 1 +ATOM 9799 C CG . MET C 1 415 ? -62.962 -1.958 -126.784 1.00 45.54 ? 477 MET B CG 1 +ATOM 9800 S SD . MET C 1 415 ? -61.373 -1.239 -126.331 1.00 38.00 ? 477 MET B SD 1 +ATOM 9801 C CE . MET C 1 415 ? -60.942 -2.223 -124.902 1.00 38.00 ? 477 MET B CE 1 +ATOM 9802 N N . ARG C 1 416 ? -62.646 -5.993 -128.936 1.00 40.24 ? 478 ARG B N 1 +ATOM 9803 C CA . ARG C 1 416 ? -62.173 -7.368 -129.076 1.00 38.00 ? 478 ARG B CA 1 +ATOM 9804 C C . ARG C 1 416 ? -61.199 -7.508 -130.235 1.00 42.08 ? 478 ARG B C 1 +ATOM 9805 O O . ARG C 1 416 ? -60.169 -8.182 -130.111 1.00 42.56 ? 478 ARG B O 1 +ATOM 9806 C CB . ARG C 1 416 ? -63.362 -8.301 -129.271 1.00 42.49 ? 478 ARG B CB 1 +ATOM 9807 C CG . ARG C 1 416 ? -63.020 -9.761 -129.436 1.00 38.00 ? 478 ARG B CG 1 +ATOM 9808 C CD . ARG C 1 416 ? -64.150 -10.449 -130.168 1.00 51.49 ? 478 ARG B CD 1 +ATOM 9809 N NE . ARG C 1 416 ? -65.434 -9.803 -129.901 1.00 54.71 ? 478 ARG B NE 1 +ATOM 9810 C CZ . ARG C 1 416 ? -66.186 -10.038 -128.830 1.00 64.80 ? 478 ARG B CZ 1 +ATOM 9811 N NH1 . ARG C 1 416 ? -65.774 -10.912 -127.919 1.00 68.84 ? 478 ARG B NH1 1 +ATOM 9812 N NH2 . ARG C 1 416 ? -67.342 -9.397 -128.669 1.00 53.25 ? 478 ARG B NH2 1 +ATOM 9813 N N . GLU C 1 417 ? -61.498 -6.857 -131.365 1.00 45.27 ? 479 GLU B N 1 +ATOM 9814 C CA . GLU C 1 417 ? -60.637 -6.954 -132.542 1.00 40.88 ? 479 GLU B CA 1 +ATOM 9815 C C . GLU C 1 417 ? -59.357 -6.143 -132.359 1.00 38.00 ? 479 GLU B C 1 +ATOM 9816 O O . GLU C 1 417 ? -58.260 -6.632 -132.656 1.00 38.00 ? 479 GLU B O 1 +ATOM 9817 C CB . GLU C 1 417 ? -61.411 -6.497 -133.783 1.00 38.00 ? 479 GLU B CB 1 +ATOM 9818 C CG . GLU C 1 417 ? -60.744 -6.815 -135.112 1.00 38.00 ? 479 GLU B CG 1 +ATOM 9819 C CD . GLU C 1 417 ? -61.560 -6.353 -136.317 1.00 48.08 ? 479 GLU B CD 1 +ATOM 9820 O OE1 . GLU C 1 417 ? -62.753 -6.014 -136.148 1.00 48.88 ? 479 GLU B OE1 1 +ATOM 9821 O OE2 . GLU C 1 417 ? -61.007 -6.336 -137.439 1.00 48.75 ? 479 GLU B OE2 1 +ATOM 9822 N N . SER C 1 418 ? -59.473 -4.913 -131.847 1.00 38.00 ? 480 SER B N 1 +ATOM 9823 C CA . SER C 1 418 ? -58.289 -4.093 -131.615 1.00 38.00 ? 480 SER B CA 1 +ATOM 9824 C C . SER C 1 418 ? -57.341 -4.746 -130.619 1.00 38.00 ? 480 SER B C 1 +ATOM 9825 O O . SER C 1 418 ? -56.120 -4.619 -130.748 1.00 41.67 ? 480 SER B O 1 +ATOM 9826 C CB . SER C 1 418 ? -58.701 -2.705 -131.122 1.00 38.00 ? 480 SER B CB 1 +ATOM 9827 O OG . SER C 1 418 ? -57.580 -1.941 -130.707 1.00 38.00 ? 480 SER B OG 1 +ATOM 9828 N N . LEU C 1 419 ? -57.875 -5.461 -129.633 1.00 41.57 ? 481 LEU B N 1 +ATOM 9829 C CA . LEU C 1 419 ? -57.016 -6.125 -128.666 1.00 39.87 ? 481 LEU B CA 1 +ATOM 9830 C C . LEU C 1 419 ? -56.395 -7.395 -129.217 1.00 38.03 ? 481 LEU B C 1 +ATOM 9831 O O . LEU C 1 419 ? -55.535 -7.981 -128.554 1.00 43.45 ? 481 LEU B O 1 +ATOM 9832 C CB . LEU C 1 419 ? -57.789 -6.453 -127.393 1.00 46.14 ? 481 LEU B CB 1 +ATOM 9833 C CG . LEU C 1 419 ? -58.388 -5.243 -126.676 1.00 47.20 ? 481 LEU B CG 1 +ATOM 9834 C CD1 . LEU C 1 419 ? -59.382 -5.692 -125.608 1.00 46.51 ? 481 LEU B CD1 1 +ATOM 9835 C CD2 . LEU C 1 419 ? -57.310 -4.341 -126.097 1.00 38.98 ? 481 LEU B CD2 1 +ATOM 9836 N N . LEU C 1 420 ? -56.818 -7.848 -130.395 1.00 38.00 ? 482 LEU B N 1 +ATOM 9837 C CA . LEU C 1 420 ? -56.192 -9.025 -130.970 1.00 38.00 ? 482 LEU B CA 1 +ATOM 9838 C C . LEU C 1 420 ? -54.796 -8.721 -131.483 1.00 40.13 ? 482 LEU B C 1 +ATOM 9839 O O . LEU C 1 420 ? -53.976 -9.639 -131.588 1.00 41.31 ? 482 LEU B O 1 +ATOM 9840 C CB . LEU C 1 420 ? -57.053 -9.587 -132.096 1.00 38.00 ? 482 LEU B CB 1 +ATOM 9841 C CG . LEU C 1 420 ? -58.226 -10.463 -131.665 1.00 38.00 ? 482 LEU B CG 1 +ATOM 9842 C CD1 . LEU C 1 420 ? -59.038 -10.880 -132.869 1.00 38.00 ? 482 LEU B CD1 1 +ATOM 9843 C CD2 . LEU C 1 420 ? -57.701 -11.682 -130.935 1.00 42.92 ? 482 LEU B CD2 1 +ATOM 9844 N N . GLU C 1 421 ? -54.492 -7.450 -131.759 1.00 38.00 ? 483 GLU B N 1 +ATOM 9845 C CA . GLU C 1 421 ? -53.179 -7.074 -132.270 1.00 39.67 ? 483 GLU B CA 1 +ATOM 9846 C C . GLU C 1 421 ? -52.097 -7.126 -131.204 1.00 45.06 ? 483 GLU B C 1 +ATOM 9847 O O . GLU C 1 421 ? -50.956 -6.745 -131.486 1.00 56.00 ? 483 GLU B O 1 +ATOM 9848 C CB . GLU C 1 421 ? -53.224 -5.665 -132.866 1.00 38.00 ? 483 GLU B CB 1 +ATOM 9849 C CG . GLU C 1 421 ? -54.564 -5.280 -133.459 1.00 38.48 ? 483 GLU B CG 1 +ATOM 9850 C CD . GLU C 1 421 ? -54.608 -3.814 -133.883 1.00 44.79 ? 483 GLU B CD 1 +ATOM 9851 O OE1 . GLU C 1 421 ? -54.156 -2.955 -133.085 1.00 38.00 ? 483 GLU B OE1 1 +ATOM 9852 O OE2 . GLU C 1 421 ? -55.127 -3.516 -134.988 1.00 39.37 ? 483 GLU B OE2 1 +ATOM 9853 N N . ASP C 1 422 ? -52.414 -7.576 -129.998 1.00 44.44 ? 484 ASP B N 1 +ATOM 9854 C CA . ASP C 1 422 ? -51.448 -7.617 -128.916 1.00 41.71 ? 484 ASP B CA 1 +ATOM 9855 C C . ASP C 1 422 ? -50.964 -9.039 -128.674 1.00 39.73 ? 484 ASP B C 1 +ATOM 9856 O O . ASP C 1 422 ? -51.729 -10.001 -128.774 1.00 42.65 ? 484 ASP B O 1 +ATOM 9857 C CB . ASP C 1 422 ? -52.051 -7.059 -127.632 1.00 41.82 ? 484 ASP B CB 1 +ATOM 9858 C CG . ASP C 1 422 ? -51.003 -6.710 -126.620 1.00 42.28 ? 484 ASP B CG 1 +ATOM 9859 O OD1 . ASP C 1 422 ? -49.810 -6.786 -126.966 1.00 41.85 ? 484 ASP B OD1 1 +ATOM 9860 O OD2 . ASP C 1 422 ? -51.365 -6.385 -125.476 1.00 49.77 ? 484 ASP B OD2 1 +ATOM 9861 N N . GLN C 1 423 ? -49.685 -9.155 -128.313 1.00 40.64 ? 485 GLN B N 1 +ATOM 9862 C CA . GLN C 1 423 ? -49.095 -10.461 -128.064 1.00 38.00 ? 485 GLN B CA 1 +ATOM 9863 C C . GLN C 1 423 ? -49.764 -11.169 -126.902 1.00 38.00 ? 485 GLN B C 1 +ATOM 9864 O O . GLN C 1 423 ? -49.732 -12.402 -126.832 1.00 38.00 ? 485 GLN B O 1 +ATOM 9865 C CB . GLN C 1 423 ? -47.599 -10.308 -127.802 1.00 39.99 ? 485 GLN B CB 1 +ATOM 9866 C CG . GLN C 1 423 ? -46.856 -11.611 -127.694 1.00 45.71 ? 485 GLN B CG 1 +ATOM 9867 C CD . GLN C 1 423 ? -45.376 -11.431 -127.893 1.00 57.73 ? 485 GLN B CD 1 +ATOM 9868 O OE1 . GLN C 1 423 ? -44.939 -10.854 -128.896 1.00 60.57 ? 485 GLN B OE1 1 +ATOM 9869 N NE2 . GLN C 1 423 ? -44.589 -11.912 -126.937 1.00 50.20 ? 485 GLN B NE2 1 +ATOM 9870 N N . LEU C 1 424 ? -50.402 -10.418 -126.010 1.00 39.33 ? 486 LEU B N 1 +ATOM 9871 C CA . LEU C 1 424 ? -51.038 -10.977 -124.831 1.00 43.56 ? 486 LEU B CA 1 +ATOM 9872 C C . LEU C 1 424 ? -52.498 -11.348 -125.066 1.00 48.12 ? 486 LEU B C 1 +ATOM 9873 O O . LEU C 1 424 ? -53.249 -11.500 -124.096 1.00 54.37 ? 486 LEU B O 1 +ATOM 9874 C CB . LEU C 1 424 ? -50.936 -9.987 -123.672 1.00 38.00 ? 486 LEU B CB 1 +ATOM 9875 C CG . LEU C 1 424 ? -49.521 -9.625 -123.248 1.00 38.00 ? 486 LEU B CG 1 +ATOM 9876 C CD1 . LEU C 1 424 ? -49.591 -8.882 -121.943 1.00 41.82 ? 486 LEU B CD1 1 +ATOM 9877 C CD2 . LEU C 1 424 ? -48.675 -10.873 -123.110 1.00 39.44 ? 486 LEU B CD2 1 +ATOM 9878 N N . SER C 1 425 ? -52.910 -11.514 -126.316 1.00 40.35 ? 487 SER B N 1 +ATOM 9879 C CA . SER C 1 425 ? -54.298 -11.839 -126.597 1.00 38.00 ? 487 SER B CA 1 +ATOM 9880 C C . SER C 1 425 ? -54.637 -13.233 -126.074 1.00 42.55 ? 487 SER B C 1 +ATOM 9881 O O . SER C 1 425 ? -53.843 -14.165 -126.235 1.00 41.51 ? 487 SER B O 1 +ATOM 9882 C CB . SER C 1 425 ? -54.563 -11.760 -128.095 1.00 42.83 ? 487 SER B CB 1 +ATOM 9883 O OG . SER C 1 425 ? -54.419 -10.424 -128.539 1.00 52.57 ? 487 SER B OG 1 +ATOM 9884 N N . PRO C 1 426 ? -55.816 -13.412 -125.445 1.00 46.17 ? 488 PRO B N 1 +ATOM 9885 C CA . PRO C 1 426 ? -56.828 -12.367 -125.234 1.00 48.79 ? 488 PRO B CA 1 +ATOM 9886 C C . PRO C 1 426 ? -56.560 -11.512 -123.991 1.00 44.02 ? 488 PRO B C 1 +ATOM 9887 O O . PRO C 1 426 ? -56.457 -12.050 -122.891 1.00 41.14 ? 488 PRO B O 1 +ATOM 9888 C CB . PRO C 1 426 ? -58.118 -13.172 -125.076 1.00 40.64 ? 488 PRO B CB 1 +ATOM 9889 C CG . PRO C 1 426 ? -57.668 -14.449 -124.444 1.00 38.00 ? 488 PRO B CG 1 +ATOM 9890 C CD . PRO C 1 426 ? -56.275 -14.726 -124.955 1.00 38.00 ? 488 PRO B CD 1 +ATOM 9891 N N . VAL C 1 427 ? -56.469 -10.191 -124.159 1.00 42.21 ? 489 VAL B N 1 +ATOM 9892 C CA . VAL C 1 427 ? -56.148 -9.341 -123.017 1.00 41.48 ? 489 VAL B CA 1 +ATOM 9893 C C . VAL C 1 427 ? -57.360 -9.092 -122.130 1.00 42.62 ? 489 VAL B C 1 +ATOM 9894 O O . VAL C 1 427 ? -57.194 -8.782 -120.943 1.00 43.20 ? 489 VAL B O 1 +ATOM 9895 C CB . VAL C 1 427 ? -55.541 -8.004 -123.479 1.00 39.68 ? 489 VAL B CB 1 +ATOM 9896 C CG1 . VAL C 1 427 ? -54.364 -8.247 -124.406 1.00 42.54 ? 489 VAL B CG1 1 +ATOM 9897 C CG2 . VAL C 1 427 ? -56.570 -7.178 -124.163 1.00 40.78 ? 489 VAL B CG2 1 +ATOM 9898 N N . LEU C 1 428 ? -58.572 -9.220 -122.669 1.00 47.95 ? 490 LEU B N 1 +ATOM 9899 C CA . LEU C 1 428 ? -59.808 -9.084 -121.907 1.00 47.58 ? 490 LEU B CA 1 +ATOM 9900 C C . LEU C 1 428 ? -60.648 -10.334 -122.096 1.00 44.79 ? 490 LEU B C 1 +ATOM 9901 O O . LEU C 1 428 ? -60.842 -10.791 -123.227 1.00 45.03 ? 490 LEU B O 1 +ATOM 9902 C CB . LEU C 1 428 ? -60.617 -7.858 -122.341 1.00 39.10 ? 490 LEU B CB 1 +ATOM 9903 C CG . LEU C 1 428 ? -60.112 -6.505 -121.858 1.00 38.00 ? 490 LEU B CG 1 +ATOM 9904 C CD1 . LEU C 1 428 ? -61.041 -5.405 -122.313 1.00 38.00 ? 490 LEU B CD1 1 +ATOM 9905 C CD2 . LEU C 1 428 ? -59.993 -6.513 -120.350 1.00 38.00 ? 490 LEU B CD2 1 +ATOM 9906 N N . THR C 1 429 ? -61.160 -10.875 -120.997 1.00 39.76 ? 491 THR B N 1 +ATOM 9907 C CA . THR C 1 429 ? -62.049 -12.015 -121.103 1.00 46.31 ? 491 THR B CA 1 +ATOM 9908 C C . THR C 1 429 ? -63.388 -11.574 -121.700 1.00 54.60 ? 491 THR B C 1 +ATOM 9909 O O . THR C 1 429 ? -63.650 -10.384 -121.897 1.00 56.58 ? 491 THR B O 1 +ATOM 9910 C CB . THR C 1 429 ? -62.227 -12.672 -119.734 1.00 47.58 ? 491 THR B CB 1 +ATOM 9911 O OG1 . THR C 1 429 ? -63.059 -11.851 -118.907 1.00 57.89 ? 491 THR B OG1 1 +ATOM 9912 C CG2 . THR C 1 429 ? -60.880 -12.837 -119.056 1.00 39.87 ? 491 THR B CG2 1 +ATOM 9913 N N . GLU C 1 430 ? -64.230 -12.556 -122.023 1.00 58.10 ? 492 GLU B N 1 +ATOM 9914 C CA . GLU C 1 430 ? -65.515 -12.241 -122.644 1.00 52.38 ? 492 GLU B CA 1 +ATOM 9915 C C . GLU C 1 430 ? -66.447 -11.449 -121.734 1.00 45.91 ? 492 GLU B C 1 +ATOM 9916 O O . GLU C 1 430 ? -67.061 -10.485 -122.224 1.00 39.98 ? 492 GLU B O 1 +ATOM 9917 C CB . GLU C 1 430 ? -66.192 -13.530 -123.131 1.00 49.42 ? 492 GLU B CB 1 +ATOM 9918 C CG . GLU C 1 430 ? -65.662 -14.038 -124.460 1.00 61.22 ? 492 GLU B CG 1 +ATOM 9919 C CD . GLU C 1 430 ? -65.762 -12.996 -125.558 1.00 61.57 ? 492 GLU B CD 1 +ATOM 9920 O OE1 . GLU C 1 430 ? -66.839 -12.383 -125.691 1.00 55.63 ? 492 GLU B OE1 1 +ATOM 9921 O OE2 . GLU C 1 430 ? -64.769 -12.800 -126.297 1.00 59.83 ? 492 GLU B OE2 1 +ATOM 9922 N N . PRO C 1 431 ? -66.609 -11.779 -120.445 1.00 47.01 ? 493 PRO B N 1 +ATOM 9923 C CA . PRO C 1 431 ? -67.465 -10.942 -119.590 1.00 47.25 ? 493 PRO B CA 1 +ATOM 9924 C C . PRO C 1 431 ? -67.040 -9.484 -119.519 1.00 45.91 ? 493 PRO B C 1 +ATOM 9925 O O . PRO C 1 431 ? -67.908 -8.605 -119.433 1.00 46.75 ? 493 PRO B O 1 +ATOM 9926 C CB . PRO C 1 431 ? -67.351 -11.623 -118.219 1.00 45.53 ? 493 PRO B CB 1 +ATOM 9927 C CG . PRO C 1 431 ? -67.062 -13.029 -118.527 1.00 43.95 ? 493 PRO B CG 1 +ATOM 9928 C CD . PRO C 1 431 ? -66.180 -13.001 -119.734 1.00 47.97 ? 493 PRO B CD 1 +ATOM 9929 N N . HIS C 1 432 ? -65.738 -9.192 -119.556 1.00 43.74 ? 494 HIS B N 1 +ATOM 9930 C CA . HIS C 1 432 ? -65.308 -7.799 -119.497 1.00 46.76 ? 494 HIS B CA 1 +ATOM 9931 C C . HIS C 1 432 ? -65.717 -7.040 -120.753 1.00 48.49 ? 494 HIS B C 1 +ATOM 9932 O O . HIS C 1 432 ? -66.188 -5.899 -120.668 1.00 45.04 ? 494 HIS B O 1 +ATOM 9933 C CB . HIS C 1 432 ? -63.797 -7.713 -119.286 1.00 46.68 ? 494 HIS B CB 1 +ATOM 9934 C CG . HIS C 1 432 ? -63.360 -8.051 -117.895 1.00 48.83 ? 494 HIS B CG 1 +ATOM 9935 N ND1 . HIS C 1 432 ? -62.754 -9.248 -117.577 1.00 53.37 ? 494 HIS B ND1 1 +ATOM 9936 C CD2 . HIS C 1 432 ? -63.426 -7.346 -116.741 1.00 43.26 ? 494 HIS B CD2 1 +ATOM 9937 C CE1 . HIS C 1 432 ? -62.472 -9.268 -116.287 1.00 46.68 ? 494 HIS B CE1 1 +ATOM 9938 N NE2 . HIS C 1 432 ? -62.871 -8.126 -115.757 1.00 46.00 ? 494 HIS B NE2 1 +ATOM 9939 N N . LEU C 1 433 ? -65.540 -7.651 -121.926 1.00 48.80 ? 495 LEU B N 1 +ATOM 9940 C CA . LEU C 1 433 ? -65.872 -6.964 -123.169 1.00 44.78 ? 495 LEU B CA 1 +ATOM 9941 C C . LEU C 1 433 ? -67.359 -6.646 -123.235 1.00 48.28 ? 495 LEU B C 1 +ATOM 9942 O O . LEU C 1 433 ? -67.748 -5.504 -123.507 1.00 49.75 ? 495 LEU B O 1 +ATOM 9943 C CB . LEU C 1 433 ? -65.442 -7.809 -124.367 1.00 45.53 ? 495 LEU B CB 1 +ATOM 9944 C CG . LEU C 1 433 ? -63.936 -7.974 -124.562 1.00 44.27 ? 495 LEU B CG 1 +ATOM 9945 C CD1 . LEU C 1 433 ? -63.652 -9.068 -125.568 1.00 45.58 ? 495 LEU B CD1 1 +ATOM 9946 C CD2 . LEU C 1 433 ? -63.329 -6.658 -125.019 1.00 38.00 ? 495 LEU B CD2 1 +ATOM 9947 N N . LEU C 1 434 ? -68.209 -7.632 -122.932 1.00 48.16 ? 496 LEU B N 1 +ATOM 9948 C CA . LEU C 1 434 ? -69.648 -7.390 -122.960 1.00 46.78 ? 496 LEU B CA 1 +ATOM 9949 C C . LEU C 1 434 ? -70.054 -6.345 -121.938 1.00 50.03 ? 496 LEU B C 1 +ATOM 9950 O O . LEU C 1 434 ? -71.056 -5.647 -122.129 1.00 53.53 ? 496 LEU B O 1 +ATOM 9951 C CB . LEU C 1 434 ? -70.408 -8.688 -122.704 1.00 43.24 ? 496 LEU B CB 1 +ATOM 9952 C CG . LEU C 1 434 ? -70.348 -9.728 -123.816 1.00 47.04 ? 496 LEU B CG 1 +ATOM 9953 C CD1 . LEU C 1 434 ? -71.439 -10.761 -123.619 1.00 49.24 ? 496 LEU B CD1 1 +ATOM 9954 C CD2 . LEU C 1 434 ? -70.482 -9.052 -125.171 1.00 56.75 ? 496 LEU B CD2 1 +ATOM 9955 N N . ALA C 1 435 ? -69.287 -6.213 -120.855 1.00 46.20 ? 497 ALA B N 1 +ATOM 9956 C CA . ALA C 1 435 ? -69.602 -5.202 -119.858 1.00 46.97 ? 497 ALA B CA 1 +ATOM 9957 C C . ALA C 1 435 ? -69.480 -3.798 -120.430 1.00 47.25 ? 497 ALA B C 1 +ATOM 9958 O O . ALA C 1 435 ? -70.236 -2.903 -120.036 1.00 50.40 ? 497 ALA B O 1 +ATOM 9959 C CB . ALA C 1 435 ? -68.695 -5.364 -118.641 1.00 50.11 ? 497 ALA B CB 1 +ATOM 9960 N N . LEU C 1 436 ? -68.555 -3.587 -121.368 1.00 43.89 ? 498 LEU B N 1 +ATOM 9961 C CA . LEU C 1 436 ? -68.407 -2.264 -121.965 1.00 46.09 ? 498 LEU B CA 1 +ATOM 9962 C C . LEU C 1 436 ? -69.692 -1.808 -122.647 1.00 48.49 ? 498 LEU B C 1 +ATOM 9963 O O . LEU C 1 436 ? -70.074 -0.637 -122.541 1.00 49.62 ? 498 LEU B O 1 +ATOM 9964 C CB . LEU C 1 436 ? -67.237 -2.257 -122.945 1.00 41.29 ? 498 LEU B CB 1 +ATOM 9965 C CG . LEU C 1 436 ? -65.891 -2.581 -122.307 1.00 38.00 ? 498 LEU B CG 1 +ATOM 9966 C CD1 . LEU C 1 436 ? -64.828 -2.700 -123.361 1.00 38.16 ? 498 LEU B CD1 1 +ATOM 9967 C CD2 . LEU C 1 436 ? -65.536 -1.498 -121.334 1.00 38.00 ? 498 LEU B CD2 1 +ATOM 9968 N N . ASP C 1 437 ? -70.379 -2.717 -123.344 1.00 48.16 ? 499 ASP B N 1 +ATOM 9969 C CA . ASP C 1 437 ? -71.642 -2.353 -123.982 1.00 59.92 ? 499 ASP B CA 1 +ATOM 9970 C C . ASP C 1 437 ? -72.678 -1.932 -122.948 1.00 55.98 ? 499 ASP B C 1 +ATOM 9971 O O . ASP C 1 437 ? -73.319 -0.882 -123.082 1.00 53.76 ? 499 ASP B O 1 +ATOM 9972 C CB . ASP C 1 437 ? -72.175 -3.520 -124.814 1.00 67.95 ? 499 ASP B CB 1 +ATOM 9973 C CG . ASP C 1 437 ? -71.384 -3.744 -126.081 1.00 59.19 ? 499 ASP B CG 1 +ATOM 9974 O OD1 . ASP C 1 437 ? -70.778 -2.775 -126.588 1.00 59.81 ? 499 ASP B OD1 1 +ATOM 9975 O OD2 . ASP C 1 437 ? -71.383 -4.890 -126.575 1.00 59.67 ? 499 ASP B OD2 1 +ATOM 9976 N N . ARG C 1 438 ? -72.859 -2.753 -121.912 1.00 54.09 ? 500 ARG B N 1 +ATOM 9977 C CA . ARG C 1 438 ? -73.858 -2.470 -120.888 1.00 53.48 ? 500 ARG B CA 1 +ATOM 9978 C C . ARG C 1 438 ? -73.562 -1.162 -120.166 1.00 47.86 ? 500 ARG B C 1 +ATOM 9979 O O . ARG C 1 438 ? -74.462 -0.336 -119.967 1.00 45.15 ? 500 ARG B O 1 +ATOM 9980 C CB . ARG C 1 438 ? -73.912 -3.638 -119.906 1.00 53.17 ? 500 ARG B CB 1 +ATOM 9981 C CG . ARG C 1 438 ? -74.676 -3.378 -118.628 1.00 55.08 ? 500 ARG B CG 1 +ATOM 9982 C CD . ARG C 1 438 ? -74.455 -4.529 -117.662 1.00 49.69 ? 500 ARG B CD 1 +ATOM 9983 N NE . ARG C 1 438 ? -73.049 -4.918 -117.594 1.00 42.65 ? 500 ARG B NE 1 +ATOM 9984 C CZ . ARG C 1 438 ? -72.531 -5.683 -116.639 1.00 48.90 ? 500 ARG B CZ 1 +ATOM 9985 N NH1 . ARG C 1 438 ? -73.304 -6.146 -115.667 1.00 57.79 ? 500 ARG B NH1 1 +ATOM 9986 N NH2 . ARG C 1 438 ? -71.241 -5.983 -116.650 1.00 49.34 ? 500 ARG B NH2 1 +ATOM 9987 N N . ARG C 1 439 ? -72.300 -0.945 -119.785 1.00 46.22 ? 501 ARG B N 1 +ATOM 9988 C CA . ARG C 1 439 ? -71.934 0.304 -119.128 1.00 48.42 ? 501 ARG B CA 1 +ATOM 9989 C C . ARG C 1 439 ? -72.099 1.494 -120.060 1.00 48.34 ? 501 ARG B C 1 +ATOM 9990 O O . ARG C 1 439 ? -72.353 2.611 -119.596 1.00 45.09 ? 501 ARG B O 1 +ATOM 9991 C CB . ARG C 1 439 ? -70.495 0.236 -118.615 1.00 45.61 ? 501 ARG B CB 1 +ATOM 9992 C CG . ARG C 1 439 ? -70.237 -0.893 -117.630 1.00 45.45 ? 501 ARG B CG 1 +ATOM 9993 C CD . ARG C 1 439 ? -68.927 -0.700 -116.885 1.00 44.07 ? 501 ARG B CD 1 +ATOM 9994 N NE . ARG C 1 439 ? -68.584 -1.879 -116.098 1.00 48.84 ? 501 ARG B NE 1 +ATOM 9995 C CZ . ARG C 1 439 ? -67.570 -2.689 -116.380 1.00 46.36 ? 501 ARG B CZ 1 +ATOM 9996 N NH1 . ARG C 1 439 ? -66.795 -2.433 -117.423 1.00 42.74 ? 501 ARG B NH1 1 +ATOM 9997 N NH2 . ARG C 1 439 ? -67.329 -3.749 -115.617 1.00 45.33 ? 501 ARG B NH2 1 +ATOM 9998 N N . LEU C 1 440 ? -71.977 1.274 -121.372 1.00 52.90 ? 502 LEU B N 1 +ATOM 9999 C CA . LEU C 1 440 ? -72.202 2.358 -122.322 1.00 55.85 ? 502 LEU B CA 1 +ATOM 10000 C C . LEU C 1 440 ? -73.660 2.804 -122.300 1.00 53.26 ? 502 LEU B C 1 +ATOM 10001 O O . LEU C 1 440 ? -73.947 4.008 -122.317 1.00 46.95 ? 502 LEU B O 1 +ATOM 10002 C CB . LEU C 1 440 ? -71.776 1.918 -123.728 1.00 53.46 ? 502 LEU B CB 1 +ATOM 10003 C CG . LEU C 1 440 ? -71.965 2.874 -124.913 1.00 54.87 ? 502 LEU B CG 1 +ATOM 10004 C CD1 . LEU C 1 440 ? -71.052 4.085 -124.824 1.00 44.55 ? 502 LEU B CD1 1 +ATOM 10005 C CD2 . LEU C 1 440 ? -71.737 2.137 -126.220 1.00 51.49 ? 502 LEU B CD2 1 +ATOM 10006 N N . GLN C 1 441 ? -74.589 1.847 -122.219 1.00 54.26 ? 503 GLN B N 1 +ATOM 10007 C CA . GLN C 1 441 ? -76.000 2.196 -122.101 1.00 53.54 ? 503 GLN B CA 1 +ATOM 10008 C C . GLN C 1 441 ? -76.247 3.043 -120.866 1.00 52.66 ? 503 GLN B C 1 +ATOM 10009 O O . GLN C 1 441 ? -76.988 4.031 -120.921 1.00 56.14 ? 503 GLN B O 1 +ATOM 10010 C CB . GLN C 1 441 ? -76.854 0.930 -122.056 1.00 54.89 ? 503 GLN B CB 1 +ATOM 10011 C CG . GLN C 1 441 ? -76.933 0.194 -123.371 1.00 57.16 ? 503 GLN B CG 1 +ATOM 10012 C CD . GLN C 1 441 ? -77.662 1.003 -124.423 1.00 65.11 ? 503 GLN B CD 1 +ATOM 10013 O OE1 . GLN C 1 441 ? -78.746 1.532 -124.171 1.00 70.33 ? 503 GLN B OE1 1 +ATOM 10014 N NE2 . GLN C 1 441 ? -77.074 1.103 -125.609 1.00 69.93 ? 503 GLN B NE2 1 +ATOM 10015 N N . THR C 1 442 ? -75.626 2.677 -119.745 1.00 47.27 ? 504 THR B N 1 +ATOM 10016 C CA . THR C 1 442 ? -75.803 3.440 -118.517 1.00 46.27 ? 504 THR B CA 1 +ATOM 10017 C C . THR C 1 442 ? -75.331 4.880 -118.689 1.00 48.24 ? 504 THR B C 1 +ATOM 10018 O O . THR C 1 442 ? -75.931 5.810 -118.137 1.00 44.83 ? 504 THR B O 1 +ATOM 10019 C CB . THR C 1 442 ? -75.066 2.742 -117.378 1.00 41.05 ? 504 THR B CB 1 +ATOM 10020 O OG1 . THR C 1 442 ? -75.575 1.409 -117.247 1.00 38.00 ? 504 THR B OG1 1 +ATOM 10021 C CG2 . THR C 1 442 ? -75.259 3.485 -116.074 1.00 43.19 ? 504 THR B CG2 1 +ATOM 10022 N N . ILE C 1 443 ? -74.269 5.090 -119.466 1.00 48.76 ? 505 ILE B N 1 +ATOM 10023 C CA . ILE C 1 443 ? -73.821 6.452 -119.736 1.00 50.34 ? 505 ILE B CA 1 +ATOM 10024 C C . ILE C 1 443 ? -74.812 7.160 -120.649 1.00 47.69 ? 505 ILE B C 1 +ATOM 10025 O O . ILE C 1 443 ? -75.239 8.287 -120.375 1.00 46.29 ? 505 ILE B O 1 +ATOM 10026 C CB . ILE C 1 443 ? -72.403 6.442 -120.332 1.00 50.07 ? 505 ILE B CB 1 +ATOM 10027 C CG1 . ILE C 1 443 ? -71.459 5.677 -119.417 1.00 48.61 ? 505 ILE B CG1 1 +ATOM 10028 C CG2 . ILE C 1 443 ? -71.874 7.855 -120.490 1.00 46.01 ? 505 ILE B CG2 1 +ATOM 10029 C CD1 . ILE C 1 443 ? -70.127 5.408 -120.034 1.00 51.72 ? 505 ILE B CD1 1 +ATOM 10030 N N . LEU C 1 444 ? -75.225 6.492 -121.726 1.00 47.30 ? 506 LEU B N 1 +ATOM 10031 C CA . LEU C 1 444 ? -76.176 7.106 -122.645 1.00 49.11 ? 506 LEU B CA 1 +ATOM 10032 C C . LEU C 1 444 ? -77.516 7.344 -121.969 1.00 51.25 ? 506 LEU B C 1 +ATOM 10033 O O . LEU C 1 444 ? -78.107 8.420 -122.112 1.00 50.18 ? 506 LEU B O 1 +ATOM 10034 C CB . LEU C 1 444 ? -76.353 6.220 -123.873 1.00 49.92 ? 506 LEU B CB 1 +ATOM 10035 C CG . LEU C 1 444 ? -75.122 6.100 -124.758 1.00 44.79 ? 506 LEU B CG 1 +ATOM 10036 C CD1 . LEU C 1 444 ? -75.369 5.061 -125.830 1.00 42.64 ? 506 LEU B CD1 1 +ATOM 10037 C CD2 . LEU C 1 444 ? -74.812 7.457 -125.363 1.00 42.75 ? 506 LEU B CD2 1 +ATOM 10038 N N . ARG C 1 445 ? -77.995 6.361 -121.206 1.00 56.27 ? 507 ARG B N 1 +ATOM 10039 C CA . ARG C 1 445 ? -79.240 6.538 -120.470 1.00 57.43 ? 507 ARG B CA 1 +ATOM 10040 C C . ARG C 1 445 ? -79.127 7.684 -119.477 1.00 55.73 ? 507 ARG B C 1 +ATOM 10041 O O . ARG C 1 445 ? -80.112 8.388 -119.229 1.00 59.82 ? 507 ARG B O 1 +ATOM 10042 C CB . ARG C 1 445 ? -79.616 5.235 -119.763 1.00 56.67 ? 507 ARG B CB 1 +ATOM 10043 C CG . ARG C 1 445 ? -80.879 5.291 -118.918 1.00 59.98 ? 507 ARG B CG 1 +ATOM 10044 C CD . ARG C 1 445 ? -81.345 3.886 -118.532 1.00 61.95 ? 507 ARG B CD 1 +ATOM 10045 N NE . ARG C 1 445 ? -80.268 3.066 -117.980 1.00 55.21 ? 507 ARG B NE 1 +ATOM 10046 C CZ . ARG C 1 445 ? -79.638 2.111 -118.656 1.00 47.69 ? 507 ARG B CZ 1 +ATOM 10047 N NH1 . ARG C 1 445 ? -79.976 1.865 -119.914 1.00 46.11 ? 507 ARG B NH1 1 +ATOM 10048 N NH2 . ARG C 1 445 ? -78.668 1.414 -118.079 1.00 43.54 ? 507 ARG B NH2 1 +ATOM 10049 N N . THR C 1 446 ? -77.930 7.899 -118.920 1.00 50.78 ? 508 THR B N 1 +ATOM 10050 C CA . THR C 1 446 ? -77.718 9.011 -117.998 1.00 52.02 ? 508 THR B CA 1 +ATOM 10051 C C . THR C 1 446 ? -77.793 10.348 -118.725 1.00 55.83 ? 508 THR B C 1 +ATOM 10052 O O . THR C 1 446 ? -78.326 11.327 -118.189 1.00 54.70 ? 508 THR B O 1 +ATOM 10053 C CB . THR C 1 446 ? -76.365 8.866 -117.301 1.00 46.35 ? 508 THR B CB 1 +ATOM 10054 O OG1 . THR C 1 446 ? -76.309 7.609 -116.617 1.00 40.11 ? 508 THR B OG1 1 +ATOM 10055 C CG2 . THR C 1 446 ? -76.162 9.992 -116.294 1.00 49.62 ? 508 THR B CG2 1 +ATOM 10056 N N . VAL C 1 447 ? -77.250 10.414 -119.941 1.00 53.63 ? 509 VAL B N 1 +ATOM 10057 C CA . VAL C 1 447 ? -77.315 11.652 -120.710 1.00 53.78 ? 509 VAL B CA 1 +ATOM 10058 C C . VAL C 1 447 ? -78.765 11.991 -121.023 1.00 60.47 ? 509 VAL B C 1 +ATOM 10059 O O . VAL C 1 447 ? -79.277 13.044 -120.625 1.00 64.90 ? 509 VAL B O 1 +ATOM 10060 C CB . VAL C 1 447 ? -76.471 11.535 -121.990 1.00 47.20 ? 509 VAL B CB 1 +ATOM 10061 C CG1 . VAL C 1 447 ? -76.626 12.781 -122.847 1.00 46.35 ? 509 VAL B CG1 1 +ATOM 10062 C CG2 . VAL C 1 447 ? -75.009 11.315 -121.634 1.00 45.71 ? 509 VAL B CG2 1 +ATOM 10063 N N . GLU C 1 448 ? -79.467 11.065 -121.680 1.00 62.47 ? 510 GLU B N 1 +ATOM 10064 C CA . GLU C 1 448 ? -80.869 11.294 -122.010 1.00 74.04 ? 510 GLU B CA 1 +ATOM 10065 C C . GLU C 1 448 ? -81.732 11.374 -120.758 1.00 70.99 ? 510 GLU B C 1 +ATOM 10066 O O . GLU C 1 448 ? -82.766 12.053 -120.763 1.00 74.29 ? 510 GLU B O 1 +ATOM 10067 C CB . GLU C 1 448 ? -81.372 10.191 -122.946 1.00 81.34 ? 510 GLU B CB 1 +ATOM 10068 C CG . GLU C 1 448 ? -81.787 8.891 -122.248 1.00 79.37 ? 510 GLU B CG 1 +ATOM 10069 C CD . GLU C 1 448 ? -82.295 7.839 -123.221 1.00 84.61 ? 510 GLU B CD 1 +ATOM 10070 O OE1 . GLU C 1 448 ? -82.824 8.220 -124.287 1.00 97.49 ? 510 GLU B OE1 1 +ATOM 10071 O OE2 . GLU C 1 448 ? -82.165 6.631 -122.922 1.00 84.94 ? 510 GLU B OE2 1 +ATOM 10072 N N . GLY C 1 449 ? -81.309 10.724 -119.673 1.00 65.75 ? 511 GLY B N 1 +ATOM 10073 C CA . GLY C 1 449 ? -82.100 10.753 -118.455 1.00 69.61 ? 511 GLY B CA 1 +ATOM 10074 C C . GLY C 1 449 ? -82.142 12.135 -117.836 1.00 66.46 ? 511 GLY B C 1 +ATOM 10075 O O . GLY C 1 449 ? -83.212 12.642 -117.492 1.00 67.60 ? 511 GLY B O 1 +ATOM 10076 N N . CYS C 1 450 ? -80.981 12.762 -117.685 1.00 65.79 ? 512 CYS B N 1 +ATOM 10077 C CA . CYS C 1 450 ? -80.929 14.103 -117.128 1.00 75.15 ? 512 CYS B CA 1 +ATOM 10078 C C . CYS C 1 450 ? -81.103 15.182 -118.193 1.00 70.56 ? 512 CYS B C 1 +ATOM 10079 O O . CYS C 1 450 ? -81.127 16.370 -117.855 1.00 72.11 ? 512 CYS B O 1 +ATOM 10080 C CB . CYS C 1 450 ? -79.626 14.292 -116.328 1.00 78.36 ? 512 CYS B CB 1 +ATOM 10081 S SG . CYS C 1 450 ? -78.128 14.697 -117.249 1.00 68.07 ? 512 CYS B SG 1 +ATOM 10082 N N . ILE C 1 451 ? -81.283 14.795 -119.458 1.00 65.17 ? 513 ILE B N 1 +ATOM 10083 C CA . ILE C 1 451 ? -81.685 15.759 -120.478 1.00 69.72 ? 513 ILE B CA 1 +ATOM 10084 C C . ILE C 1 451 ? -83.107 16.248 -120.222 1.00 73.61 ? 513 ILE B C 1 +ATOM 10085 O O . ILE C 1 451 ? -83.413 17.430 -120.416 1.00 69.74 ? 513 ILE B O 1 +ATOM 10086 C CB . ILE C 1 451 ? -81.533 15.141 -121.881 1.00 69.66 ? 513 ILE B CB 1 +ATOM 10087 C CG1 . ILE C 1 451 ? -80.272 15.672 -122.563 1.00 71.45 ? 513 ILE B CG1 1 +ATOM 10088 C CG2 . ILE C 1 451 ? -82.754 15.413 -122.745 1.00 69.49 ? 513 ILE B CG2 1 +ATOM 10089 C CD1 . ILE C 1 451 ? -80.076 15.155 -123.971 1.00 66.32 ? 513 ILE B CD1 1 +ATOM 10090 N N . VAL C 1 452 ? -83.987 15.359 -119.750 1.00 75.45 ? 514 VAL B N 1 +ATOM 10091 C CA . VAL C 1 452 ? -85.383 15.718 -119.507 1.00 76.21 ? 514 VAL B CA 1 +ATOM 10092 C C . VAL C 1 452 ? -85.523 16.775 -118.421 1.00 77.96 ? 514 VAL B C 1 +ATOM 10093 O O . VAL C 1 452 ? -86.546 17.469 -118.360 1.00 88.48 ? 514 VAL B O 1 +ATOM 10094 C CB . VAL C 1 452 ? -86.207 14.463 -119.146 1.00 69.18 ? 514 VAL B CB 1 +ATOM 10095 C CG1 . VAL C 1 452 ? -85.833 13.302 -120.055 1.00 61.94 ? 514 VAL B CG1 1 +ATOM 10096 C CG2 . VAL C 1 452 ? -86.024 14.100 -117.672 1.00 63.02 ? 514 VAL B CG2 1 +ATOM 10097 N N . ALA C 1 453 ? -84.520 16.919 -117.557 1.00 73.38 ? 515 ALA B N 1 +ATOM 10098 C CA . ALA C 1 453 ? -84.572 17.893 -116.481 1.00 71.53 ? 515 ALA B CA 1 +ATOM 10099 C C . ALA C 1 453 ? -83.881 19.201 -116.832 1.00 72.04 ? 515 ALA B C 1 +ATOM 10100 O O . ALA C 1 453 ? -84.117 20.207 -116.155 1.00 77.83 ? 515 ALA B O 1 +ATOM 10101 C CB . ALA C 1 453 ? -83.939 17.307 -115.213 1.00 67.32 ? 515 ALA B CB 1 +ATOM 10102 N N . HIS C 1 454 ? -83.059 19.219 -117.883 1.00 66.85 ? 516 HIS B N 1 +ATOM 10103 C CA . HIS C 1 454 ? -82.336 20.419 -118.279 1.00 73.39 ? 516 HIS B CA 1 +ATOM 10104 C C . HIS C 1 454 ? -82.408 20.712 -119.772 1.00 72.35 ? 516 HIS B C 1 +ATOM 10105 O O . HIS C 1 454 ? -82.082 21.837 -120.172 1.00 71.15 ? 516 HIS B O 1 +ATOM 10106 C CB . HIS C 1 454 ? -80.857 20.319 -117.869 1.00 75.30 ? 516 HIS B CB 1 +ATOM 10107 C CG . HIS C 1 454 ? -80.642 20.055 -116.409 1.00 68.77 ? 516 HIS B CG 1 +ATOM 10108 N ND1 . HIS C 1 454 ? -80.976 18.858 -115.811 1.00 62.71 ? 516 HIS B ND1 1 +ATOM 10109 C CD2 . HIS C 1 454 ? -80.101 20.823 -115.434 1.00 63.04 ? 516 HIS B CD2 1 +ATOM 10110 C CE1 . HIS C 1 454 ? -80.662 18.904 -114.528 1.00 57.95 ? 516 HIS B CE1 1 +ATOM 10111 N NE2 . HIS C 1 454 ? -80.129 20.086 -114.274 1.00 59.78 ? 516 HIS B NE2 1 +ATOM 10112 N N . GLY C 1 455 ? -82.824 19.755 -120.602 1.00 68.67 ? 517 GLY B N 1 +ATOM 10113 C CA . GLY C 1 455 ? -82.887 19.960 -122.034 1.00 72.61 ? 517 GLY B CA 1 +ATOM 10114 C C . GLY C 1 455 ? -81.526 19.920 -122.701 1.00 78.86 ? 517 GLY B C 1 +ATOM 10115 O O . GLY C 1 455 ? -80.475 19.991 -122.067 1.00 81.37 ? 517 GLY B O 1 +ATOM 10116 N N . GLN C 1 456 ? -81.551 19.821 -124.028 1.00 69.32 ? 518 GLN B N 1 +ATOM 10117 C CA . GLN C 1 456 ? -80.303 19.810 -124.793 1.00 64.07 ? 518 GLN B CA 1 +ATOM 10118 C C . GLN C 1 456 ? -79.530 21.122 -124.689 1.00 67.36 ? 518 GLN B C 1 +ATOM 10119 O O . GLN C 1 456 ? -78.464 21.237 -125.297 1.00 61.97 ? 518 GLN B O 1 +ATOM 10120 C CB . GLN C 1 456 ? -80.606 19.492 -126.258 1.00 61.93 ? 518 GLN B CB 1 +ATOM 10121 C CG . GLN C 1 456 ? -81.158 18.099 -126.467 1.00 61.55 ? 518 GLN B CG 1 +ATOM 10122 C CD . GLN C 1 456 ? -81.221 17.713 -127.931 1.00 78.06 ? 518 GLN B CD 1 +ATOM 10123 O OE1 . GLN C 1 456 ? -80.620 18.363 -128.794 1.00 86.73 ? 518 GLN B OE1 1 +ATOM 10124 N NE2 . GLN C 1 456 ? -81.978 16.669 -128.225 1.00 68.19 ? 518 GLN B NE2 1 +ATOM 10125 N N . GLN C 1 457 ? -80.052 22.109 -123.960 1.00 77.20 ? 519 GLN B N 1 +ATOM 10126 C CA . GLN C 1 457 ? -79.351 23.374 -123.762 1.00 77.67 ? 519 GLN B CA 1 +ATOM 10127 C C . GLN C 1 457 ? -78.086 23.192 -122.927 1.00 79.26 ? 519 GLN B C 1 +ATOM 10128 O O . GLN C 1 457 ? -76.979 23.537 -123.362 1.00 79.45 ? 519 GLN B O 1 +ATOM 10129 C CB . GLN C 1 457 ? -80.293 24.391 -123.099 1.00 91.23 ? 519 GLN B CB 1 +ATOM 10130 C CG . GLN C 1 457 ? -79.623 25.500 -122.255 1.00 106.67 ? 519 GLN B CG 1 +ATOM 10131 C CD . GLN C 1 457 ? -80.196 25.620 -120.831 1.00 98.36 ? 519 GLN B CD 1 +ATOM 10132 O OE1 . GLN C 1 457 ? -80.576 24.622 -120.210 1.00 81.40 ? 519 GLN B OE1 1 +ATOM 10133 N NE2 . GLN C 1 457 ? -80.256 26.851 -120.316 1.00 97.48 ? 519 GLN B NE2 1 +ATOM 10134 N N . SER C 1 458 ? -78.229 22.652 -121.717 1.00 75.61 ? 520 SER B N 1 +ATOM 10135 C CA . SER C 1 458 ? -77.126 22.588 -120.770 1.00 77.82 ? 520 SER B CA 1 +ATOM 10136 C C . SER C 1 458 ? -76.554 21.185 -120.628 1.00 71.72 ? 520 SER B C 1 +ATOM 10137 O O . SER C 1 458 ? -75.675 20.971 -119.789 1.00 69.41 ? 520 SER B O 1 +ATOM 10138 C CB . SER C 1 458 ? -77.567 23.125 -119.406 1.00 84.76 ? 520 SER B CB 1 +ATOM 10139 O OG . SER C 1 458 ? -76.506 23.065 -118.466 1.00 83.75 ? 520 SER B OG 1 +ATOM 10140 N N . VAL C 1 459 ? -77.023 20.226 -121.426 1.00 69.94 ? 521 VAL B N 1 +ATOM 10141 C CA . VAL C 1 459 ? -76.499 18.865 -121.398 1.00 65.07 ? 521 VAL B CA 1 +ATOM 10142 C C . VAL C 1 459 ? -75.693 18.526 -122.644 1.00 61.55 ? 521 VAL B C 1 +ATOM 10143 O O . VAL C 1 459 ? -75.102 17.439 -122.711 1.00 63.89 ? 521 VAL B O 1 +ATOM 10144 C CB . VAL C 1 459 ? -77.627 17.838 -121.178 1.00 62.23 ? 521 VAL B CB 1 +ATOM 10145 C CG1 . VAL C 1 459 ? -77.068 16.525 -120.661 1.00 54.92 ? 521 VAL B CG1 1 +ATOM 10146 C CG2 . VAL C 1 459 ? -78.632 18.376 -120.182 1.00 67.63 ? 521 VAL B CG2 1 +ATOM 10147 N N . ILE C 1 460 ? -75.621 19.428 -123.621 1.00 65.24 ? 522 ILE B N 1 +ATOM 10148 C CA . ILE C 1 460 ? -74.779 19.261 -124.801 1.00 58.34 ? 522 ILE B CA 1 +ATOM 10149 C C . ILE C 1 460 ? -74.011 20.559 -124.988 1.00 59.67 ? 522 ILE B C 1 +ATOM 10150 O O . ILE C 1 460 ? -74.618 21.630 -125.106 1.00 68.56 ? 522 ILE B O 1 +ATOM 10151 C CB . ILE C 1 460 ? -75.589 18.924 -126.067 1.00 49.33 ? 522 ILE B CB 1 +ATOM 10152 C CG1 . ILE C 1 460 ? -75.797 17.415 -126.211 1.00 38.00 ? 522 ILE B CG1 1 +ATOM 10153 C CG2 . ILE C 1 460 ? -74.904 19.463 -127.306 1.00 53.77 ? 522 ILE B CG2 1 +ATOM 10154 C CD1 . ILE C 1 460 ? -76.944 16.873 -125.414 1.00 38.00 ? 522 ILE B CD1 1 +ATOM 10155 N N . VAL C 1 461 ? -72.692 20.472 -125.009 1.00 58.05 ? 523 VAL B N 1 +ATOM 10156 C CA . VAL C 1 461 ? -71.832 21.649 -125.117 1.00 72.40 ? 523 VAL B CA 1 +ATOM 10157 C C . VAL C 1 461 ? -71.053 21.508 -126.420 1.00 77.14 ? 523 VAL B C 1 +ATOM 10158 O O . VAL C 1 461 ? -69.951 20.956 -126.463 1.00 78.43 ? 523 VAL B O 1 +ATOM 10159 C CB . VAL C 1 461 ? -70.906 21.810 -123.910 1.00 69.72 ? 523 VAL B CB 1 +ATOM 10160 C CG1 . VAL C 1 461 ? -71.548 22.720 -122.874 1.00 65.41 ? 523 VAL B CG1 1 +ATOM 10161 C CG2 . VAL C 1 461 ? -70.619 20.461 -123.303 1.00 63.11 ? 523 VAL B CG2 1 +ATOM 10162 N N . ASP C 1 462 ? -71.639 22.013 -127.503 1.00 81.35 ? 524 ASP B N 1 +ATOM 10163 C CA . ASP C 1 462 ? -71.059 21.892 -128.835 1.00 82.36 ? 524 ASP B CA 1 +ATOM 10164 C C . ASP C 1 462 ? -69.998 22.952 -129.107 1.00 92.40 ? 524 ASP B C 1 +ATOM 10165 O O . ASP C 1 462 ? -70.010 23.580 -130.169 1.00 104.80 ? 524 ASP B O 1 +ATOM 10166 C CB . ASP C 1 462 ? -72.172 21.954 -129.884 1.00 84.69 ? 524 ASP B CB 1 +ATOM 10167 C CG . ASP C 1 462 ? -73.085 23.151 -129.691 1.00 93.85 ? 524 ASP B CG 1 +ATOM 10168 O OD1 . ASP C 1 462 ? -73.252 23.592 -128.533 1.00 91.25 ? 524 ASP B OD1 1 +ATOM 10169 O OD2 . ASP C 1 462 ? -73.650 23.638 -130.694 1.00 95.23 ? 524 ASP B OD2 1 +ATOM 10170 N N . GLY C 1 463 ? -69.077 23.156 -128.163 1.00 88.52 ? 525 GLY B N 1 +ATOM 10171 C CA . GLY C 1 463 ? -67.959 24.046 -128.378 1.00 93.03 ? 525 GLY B CA 1 +ATOM 10172 C C . GLY C 1 463 ? -67.093 23.568 -129.529 1.00 112.29 ? 525 GLY B C 1 +ATOM 10173 O O . GLY C 1 463 ? -67.099 22.386 -129.890 1.00 114.27 ? 525 GLY B O 1 +ATOM 10174 N N . PRO C 1 464 ? -66.322 24.485 -130.138 1.00 122.71 ? 526 PRO B N 1 +ATOM 10175 C CA . PRO C 1 464 ? -65.517 24.160 -131.326 1.00 119.46 ? 526 PRO B CA 1 +ATOM 10176 C C . PRO C 1 464 ? -64.277 23.312 -131.028 1.00 107.50 ? 526 PRO B C 1 +ATOM 10177 O O . PRO C 1 464 ? -63.747 23.369 -129.918 1.00 110.55 ? 526 PRO B O 1 +ATOM 10178 C CB . PRO C 1 464 ? -65.110 25.539 -131.856 1.00 121.60 ? 526 PRO B CB 1 +ATOM 10179 C CG . PRO C 1 464 ? -65.099 26.413 -130.645 1.00 121.97 ? 526 PRO B CG 1 +ATOM 10180 C CD . PRO C 1 464 ? -66.189 25.899 -129.742 1.00 110.36 ? 526 PRO B CD 1 +ATOM 10181 N N . SER D 2 134 ? -68.452 -48.343 -88.356 1.00 80.72 ? 134 SER D N 1 +ATOM 10182 C CA . SER D 2 134 ? -68.005 -49.716 -88.534 1.00 74.62 ? 134 SER D CA 1 +ATOM 10183 C C . SER D 2 134 ? -66.487 -49.763 -88.680 1.00 75.95 ? 134 SER D C 1 +ATOM 10184 O O . SER D 2 134 ? -65.814 -50.491 -87.950 1.00 69.67 ? 134 SER D O 1 +ATOM 10185 C CB . SER D 2 134 ? -68.690 -50.354 -89.755 1.00 85.30 ? 134 SER D CB 1 +ATOM 10186 O OG . SER D 2 134 ? -68.248 -49.778 -90.977 1.00 85.81 ? 134 SER D OG 1 +ATOM 10187 N N . VAL D 2 135 ? -65.955 -48.967 -89.614 1.00 77.44 ? 135 VAL D N 1 +ATOM 10188 C CA . VAL D 2 135 ? -64.514 -48.965 -89.861 1.00 71.59 ? 135 VAL D CA 1 +ATOM 10189 C C . VAL D 2 135 ? -63.772 -48.530 -88.609 1.00 73.45 ? 135 VAL D C 1 +ATOM 10190 O O . VAL D 2 135 ? -62.827 -49.189 -88.158 1.00 75.18 ? 135 VAL D O 1 +ATOM 10191 C CB . VAL D 2 135 ? -64.170 -48.057 -91.055 1.00 59.56 ? 135 VAL D CB 1 +ATOM 10192 C CG1 . VAL D 2 135 ? -62.817 -48.436 -91.617 1.00 62.54 ? 135 VAL D CG1 1 +ATOM 10193 C CG2 . VAL D 2 135 ? -65.247 -48.136 -92.117 1.00 59.91 ? 135 VAL D CG2 1 +ATOM 10194 N N . LEU D 2 136 ? -64.190 -47.403 -88.034 1.00 75.09 ? 136 LEU D N 1 +ATOM 10195 C CA . LEU D 2 136 ? -63.598 -46.932 -86.789 1.00 81.48 ? 136 LEU D CA 1 +ATOM 10196 C C . LEU D 2 136 ? -63.889 -47.898 -85.646 1.00 81.73 ? 136 LEU D C 1 +ATOM 10197 O O . LEU D 2 136 ? -63.025 -48.146 -84.795 1.00 71.94 ? 136 LEU D O 1 +ATOM 10198 C CB . LEU D 2 136 ? -64.119 -45.533 -86.474 1.00 83.37 ? 136 LEU D CB 1 +ATOM 10199 C CG . LEU D 2 136 ? -63.258 -44.691 -85.539 1.00 80.22 ? 136 LEU D CG 1 +ATOM 10200 C CD1 . LEU D 2 136 ? -61.803 -44.750 -85.981 1.00 71.10 ? 136 LEU D CD1 1 +ATOM 10201 C CD2 . LEU D 2 136 ? -63.763 -43.258 -85.526 1.00 80.67 ? 136 LEU D CD2 1 +ATOM 10202 N N . GLN D 2 137 ? -65.105 -48.449 -85.611 1.00 78.42 ? 137 GLN D N 1 +ATOM 10203 C CA . GLN D 2 137 ? -65.445 -49.439 -84.596 1.00 75.28 ? 137 GLN D CA 1 +ATOM 10204 C C . GLN D 2 137 ? -64.462 -50.606 -84.621 1.00 72.19 ? 137 GLN D C 1 +ATOM 10205 O O . GLN D 2 137 ? -63.958 -51.026 -83.572 1.00 64.60 ? 137 GLN D O 1 +ATOM 10206 C CB . GLN D 2 137 ? -66.886 -49.923 -84.825 1.00 72.72 ? 137 GLN D CB 1 +ATOM 10207 C CG . GLN D 2 137 ? -67.488 -50.818 -83.736 1.00 75.32 ? 137 GLN D CG 1 +ATOM 10208 C CD . GLN D 2 137 ? -67.673 -50.113 -82.400 1.00 85.33 ? 137 GLN D CD 1 +ATOM 10209 O OE1 . GLN D 2 137 ? -68.127 -48.970 -82.343 1.00 93.95 ? 137 GLN D OE1 1 +ATOM 10210 N NE2 . GLN D 2 137 ? -67.327 -50.801 -81.315 1.00 82.53 ? 137 GLN D NE2 1 +ATOM 10211 N N . SER D 2 138 ? -64.106 -51.078 -85.821 1.00 76.31 ? 138 SER D N 1 +ATOM 10212 C CA . SER D 2 138 ? -63.224 -52.235 -85.946 1.00 75.35 ? 138 SER D CA 1 +ATOM 10213 C C . SER D 2 138 ? -61.779 -51.898 -85.613 1.00 71.84 ? 138 SER D C 1 +ATOM 10214 O O . SER D 2 138 ? -61.061 -52.742 -85.066 1.00 75.38 ? 138 SER D O 1 +ATOM 10215 C CB . SER D 2 138 ? -63.289 -52.800 -87.366 1.00 68.44 ? 138 SER D CB 1 +ATOM 10216 O OG . SER D 2 138 ? -64.616 -53.110 -87.750 1.00 69.64 ? 138 SER D OG 1 +ATOM 10217 N N . LEU D 2 139 ? -61.331 -50.689 -85.953 1.00 66.93 ? 139 LEU D N 1 +ATOM 10218 C CA . LEU D 2 139 ? -59.938 -50.325 -85.722 1.00 65.38 ? 139 LEU D CA 1 +ATOM 10219 C C . LEU D 2 139 ? -59.579 -50.405 -84.243 1.00 73.84 ? 139 LEU D C 1 +ATOM 10220 O O . LEU D 2 139 ? -58.592 -51.048 -83.868 1.00 73.93 ? 139 LEU D O 1 +ATOM 10221 C CB . LEU D 2 139 ? -59.662 -48.929 -86.269 1.00 63.04 ? 139 LEU D CB 1 +ATOM 10222 C CG . LEU D 2 139 ? -58.234 -48.467 -85.991 1.00 60.18 ? 139 LEU D CG 1 +ATOM 10223 C CD1 . LEU D 2 139 ? -57.232 -49.227 -86.847 1.00 51.57 ? 139 LEU D CD1 1 +ATOM 10224 C CD2 . LEU D 2 139 ? -58.128 -46.976 -86.223 1.00 66.93 ? 139 LEU D CD2 1 +ATOM 10225 N N . PHE D 2 140 ? -60.362 -49.743 -83.385 1.00 78.03 ? 140 PHE D N 1 +ATOM 10226 C CA . PHE D 2 140 ? -60.110 -49.813 -81.948 1.00 76.21 ? 140 PHE D CA 1 +ATOM 10227 C C . PHE D 2 140 ? -60.390 -51.201 -81.384 1.00 75.97 ? 140 PHE D C 1 +ATOM 10228 O O . PHE D 2 140 ? -59.948 -51.506 -80.268 1.00 76.79 ? 140 PHE D O 1 +ATOM 10229 C CB . PHE D 2 140 ? -60.941 -48.758 -81.211 1.00 75.87 ? 140 PHE D CB 1 +ATOM 10230 C CG . PHE D 2 140 ? -60.610 -47.337 -81.603 1.00 78.82 ? 140 PHE D CG 1 +ATOM 10231 C CD1 . PHE D 2 140 ? -59.347 -47.010 -82.077 1.00 69.31 ? 140 PHE D CD1 1 +ATOM 10232 C CD2 . PHE D 2 140 ? -61.560 -46.329 -81.496 1.00 90.38 ? 140 PHE D CD2 1 +ATOM 10233 C CE1 . PHE D 2 140 ? -59.040 -45.710 -82.443 1.00 70.28 ? 140 PHE D CE1 1 +ATOM 10234 C CE2 . PHE D 2 140 ? -61.257 -45.023 -81.858 1.00 83.73 ? 140 PHE D CE2 1 +ATOM 10235 C CZ . PHE D 2 140 ? -59.995 -44.716 -82.332 1.00 77.41 ? 140 PHE D CZ 1 +ATOM 10236 N N . GLU D 2 141 ? -61.101 -52.049 -82.131 1.00 76.51 ? 141 GLU D N 1 +ATOM 10237 C CA . GLU D 2 141 ? -61.331 -53.430 -81.728 1.00 79.71 ? 141 GLU D CA 1 +ATOM 10238 C C . GLU D 2 141 ? -60.164 -54.351 -82.067 1.00 80.70 ? 141 GLU D C 1 +ATOM 10239 O O . GLU D 2 141 ? -60.153 -55.500 -81.610 1.00 83.07 ? 141 GLU D O 1 +ATOM 10240 C CB . GLU D 2 141 ? -62.603 -53.954 -82.404 1.00 79.60 ? 141 GLU D CB 1 +ATOM 10241 C CG . GLU D 2 141 ? -63.850 -53.915 -81.535 1.00 84.05 ? 141 GLU D CG 1 +ATOM 10242 C CD . GLU D 2 141 ? -65.109 -54.215 -82.336 1.00 93.52 ? 141 GLU D CD 1 +ATOM 10243 O OE1 . GLU D 2 141 ? -65.335 -55.398 -82.664 1.00 94.08 ? 141 GLU D OE1 1 +ATOM 10244 O OE2 . GLU D 2 141 ? -65.885 -53.276 -82.620 1.00 85.02 ? 141 GLU D OE2 1 +ATOM 10245 N N . HIS D 2 142 ? -59.178 -53.869 -82.826 1.00 74.77 ? 142 HIS D N 1 +ATOM 10246 C CA . HIS D 2 142 ? -58.002 -54.655 -83.169 1.00 67.22 ? 142 HIS D CA 1 +ATOM 10247 C C . HIS D 2 142 ? -57.191 -54.974 -81.914 1.00 67.82 ? 142 HIS D C 1 +ATOM 10248 O O . HIS D 2 142 ? -57.315 -54.288 -80.899 1.00 75.13 ? 142 HIS D O 1 +ATOM 10249 C CB . HIS D 2 142 ? -57.136 -53.885 -84.164 1.00 68.06 ? 142 HIS D CB 1 +ATOM 10250 C CG . HIS D 2 142 ? -56.305 -54.754 -85.054 1.00 68.62 ? 142 HIS D CG 1 +ATOM 10251 N ND1 . HIS D 2 142 ? -56.841 -55.489 -86.089 1.00 69.16 ? 142 HIS D ND1 1 +ATOM 10252 C CD2 . HIS D 2 142 ? -54.978 -55.027 -85.043 1.00 61.29 ? 142 HIS D CD2 1 +ATOM 10253 C CE1 . HIS D 2 142 ? -55.876 -56.164 -86.689 1.00 67.88 ? 142 HIS D CE1 1 +ATOM 10254 N NE2 . HIS D 2 142 ? -54.737 -55.902 -86.073 1.00 62.72 ? 142 HIS D NE2 1 +ATOM 10255 N N . PRO D 2 143 ? -56.348 -56.011 -81.955 1.00 66.50 ? 143 PRO D N 1 +ATOM 10256 C CA . PRO D 2 143 ? -55.419 -56.259 -80.842 1.00 71.76 ? 143 PRO D CA 1 +ATOM 10257 C C . PRO D 2 143 ? -54.173 -55.389 -80.863 1.00 70.51 ? 143 PRO D C 1 +ATOM 10258 O O . PRO D 2 143 ? -53.347 -55.496 -79.948 1.00 66.10 ? 143 PRO D O 1 +ATOM 10259 C CB . PRO D 2 143 ? -55.052 -57.740 -81.022 1.00 66.26 ? 143 PRO D CB 1 +ATOM 10260 C CG . PRO D 2 143 ? -55.227 -57.994 -82.465 1.00 74.83 ? 143 PRO D CG 1 +ATOM 10261 C CD . PRO D 2 143 ? -56.403 -57.154 -82.883 1.00 74.34 ? 143 PRO D CD 1 +ATOM 10262 N N . LEU D 2 144 ? -54.012 -54.537 -81.868 1.00 66.56 ? 144 LEU D N 1 +ATOM 10263 C CA . LEU D 2 144 ? -52.902 -53.596 -81.911 1.00 66.28 ? 144 LEU D CA 1 +ATOM 10264 C C . LEU D 2 144 ? -53.254 -52.252 -81.295 1.00 63.85 ? 144 LEU D C 1 +ATOM 10265 O O . LEU D 2 144 ? -52.396 -51.363 -81.239 1.00 63.76 ? 144 LEU D O 1 +ATOM 10266 C CB . LEU D 2 144 ? -52.456 -53.371 -83.360 1.00 70.20 ? 144 LEU D CB 1 +ATOM 10267 C CG . LEU D 2 144 ? -51.104 -53.911 -83.823 1.00 71.50 ? 144 LEU D CG 1 +ATOM 10268 C CD1 . LEU D 2 144 ? -50.609 -53.066 -84.975 1.00 55.86 ? 144 LEU D CD1 1 +ATOM 10269 C CD2 . LEU D 2 144 ? -50.088 -53.944 -82.685 1.00 72.70 ? 144 LEU D CD2 1 +ATOM 10270 N N . TYR D 2 145 ? -54.487 -52.089 -80.819 1.00 68.48 ? 145 TYR D N 1 +ATOM 10271 C CA . TYR D 2 145 ? -54.945 -50.823 -80.261 1.00 69.80 ? 145 TYR D CA 1 +ATOM 10272 C C . TYR D 2 145 ? -55.381 -50.960 -78.809 1.00 76.48 ? 145 TYR D C 1 +ATOM 10273 O O . TYR D 2 145 ? -55.928 -50.007 -78.240 1.00 74.66 ? 145 TYR D O 1 +ATOM 10274 C CB . TYR D 2 145 ? -56.087 -50.249 -81.106 1.00 61.91 ? 145 TYR D CB 1 +ATOM 10275 C CG . TYR D 2 145 ? -55.607 -49.578 -82.371 1.00 65.19 ? 145 TYR D CG 1 +ATOM 10276 C CD1 . TYR D 2 145 ? -54.821 -50.268 -83.283 1.00 61.79 ? 145 TYR D CD1 1 +ATOM 10277 C CD2 . TYR D 2 145 ? -55.917 -48.254 -82.645 1.00 67.93 ? 145 TYR D CD2 1 +ATOM 10278 C CE1 . TYR D 2 145 ? -54.367 -49.673 -84.432 1.00 55.75 ? 145 TYR D CE1 1 +ATOM 10279 C CE2 . TYR D 2 145 ? -55.462 -47.646 -83.807 1.00 63.30 ? 145 TYR D CE2 1 +ATOM 10280 C CZ . TYR D 2 145 ? -54.686 -48.368 -84.693 1.00 51.09 ? 145 TYR D CZ 1 +ATOM 10281 O OH . TYR D 2 145 ? -54.218 -47.796 -85.847 1.00 49.87 ? 145 TYR D OH 1 +ATOM 10282 N N . ARG D 2 146 ? -55.182 -52.130 -78.207 1.00 76.09 ? 146 ARG D N 1 +ATOM 10283 C CA . ARG D 2 146 ? -55.511 -52.365 -76.812 1.00 74.73 ? 146 ARG D CA 1 +ATOM 10284 C C . ARG D 2 146 ? -54.274 -52.517 -75.940 1.00 74.30 ? 146 ARG D C 1 +ATOM 10285 O O . ARG D 2 146 ? -54.408 -52.768 -74.737 1.00 74.36 ? 146 ARG D O 1 +ATOM 10286 C CB . ARG D 2 146 ? -56.409 -53.602 -76.693 1.00 78.95 ? 146 ARG D CB 1 +ATOM 10287 C CG . ARG D 2 146 ? -57.297 -53.802 -77.914 1.00 75.82 ? 146 ARG D CG 1 +ATOM 10288 C CD . ARG D 2 146 ? -58.457 -54.749 -77.648 1.00 90.87 ? 146 ARG D CD 1 +ATOM 10289 N NE . ARG D 2 146 ? -59.562 -54.085 -76.960 1.00 103.08 ? 146 ARG D NE 1 +ATOM 10290 C CZ . ARG D 2 146 ? -60.811 -54.541 -76.930 1.00 101.00 ? 146 ARG D CZ 1 +ATOM 10291 N NH1 . ARG D 2 146 ? -61.124 -55.669 -77.556 1.00 102.02 ? 146 ARG D NH1 1 +ATOM 10292 N NH2 . ARG D 2 146 ? -61.747 -53.868 -76.273 1.00 87.66 ? 146 ARG D NH2 1 +ATOM 10293 N N . THR D 2 147 ? -53.077 -52.368 -76.512 1.00 69.33 ? 147 THR D N 1 +ATOM 10294 C CA . THR D 2 147 ? -51.838 -52.414 -75.745 1.00 72.03 ? 147 THR D CA 1 +ATOM 10295 C C . THR D 2 147 ? -51.821 -51.333 -74.676 1.00 69.90 ? 147 THR D C 1 +ATOM 10296 O O . THR D 2 147 ? -51.563 -50.164 -74.982 1.00 69.13 ? 147 THR D O 1 +ATOM 10297 C CB . THR D 2 147 ? -50.629 -52.221 -76.660 1.00 71.93 ? 147 THR D CB 1 +ATOM 10298 O OG1 . THR D 2 147 ? -50.662 -53.192 -77.710 1.00 85.99 ? 147 THR D OG1 1 +ATOM 10299 C CG2 . THR D 2 147 ? -49.337 -52.381 -75.865 1.00 62.66 ? 147 THR D CG2 1 +ATOM 10300 N N . VAL D 2 148 ? -52.071 -51.702 -73.420 1.00 70.62 ? 148 VAL D N 1 +ATOM 10301 C CA . VAL D 2 148 ? -52.060 -50.705 -72.359 1.00 74.41 ? 148 VAL D CA 1 +ATOM 10302 C C . VAL D 2 148 ? -50.628 -50.280 -72.066 1.00 77.24 ? 148 VAL D C 1 +ATOM 10303 O O . VAL D 2 148 ? -49.667 -51.035 -72.274 1.00 74.25 ? 148 VAL D O 1 +ATOM 10304 C CB . VAL D 2 148 ? -52.748 -51.221 -71.081 1.00 68.87 ? 148 VAL D CB 1 +ATOM 10305 C CG1 . VAL D 2 148 ? -54.190 -51.610 -71.368 1.00 65.58 ? 148 VAL D CG1 1 +ATOM 10306 C CG2 . VAL D 2 148 ? -51.967 -52.383 -70.482 1.00 63.21 ? 148 VAL D CG2 1 +ATOM 10307 N N . LEU D 2 149 ? -50.488 -49.056 -71.563 1.00 81.34 ? 149 LEU D N 1 +ATOM 10308 C CA . LEU D 2 149 ? -49.203 -48.574 -71.115 1.00 74.98 ? 149 LEU D CA 1 +ATOM 10309 C C . LEU D 2 149 ? -48.751 -49.387 -69.911 1.00 73.76 ? 149 LEU D C 1 +ATOM 10310 O O . LEU D 2 149 ? -49.566 -50.020 -69.235 1.00 73.45 ? 149 LEU D O 1 +ATOM 10311 C CB . LEU D 2 149 ? -49.286 -47.096 -70.732 1.00 76.76 ? 149 LEU D CB 1 +ATOM 10312 C CG . LEU D 2 149 ? -49.944 -46.095 -71.685 1.00 77.29 ? 149 LEU D CG 1 +ATOM 10313 C CD1 . LEU D 2 149 ? -50.040 -44.713 -71.036 1.00 60.43 ? 149 LEU D CD1 1 +ATOM 10314 C CD2 . LEU D 2 149 ? -49.203 -46.031 -73.018 1.00 82.48 ? 149 LEU D CD2 1 +ATOM 10315 N N . PRO D 2 150 ? -47.453 -49.389 -69.623 1.00 79.33 ? 150 PRO D N 1 +ATOM 10316 C CA . PRO D 2 150 ? -46.986 -49.946 -68.348 1.00 84.84 ? 150 PRO D CA 1 +ATOM 10317 C C . PRO D 2 150 ? -47.640 -49.232 -67.173 1.00 78.76 ? 150 PRO D C 1 +ATOM 10318 O O . PRO D 2 150 ? -48.346 -48.232 -67.323 1.00 76.96 ? 150 PRO D O 1 +ATOM 10319 C CB . PRO D 2 150 ? -45.472 -49.712 -68.395 1.00 81.65 ? 150 PRO D CB 1 +ATOM 10320 C CG . PRO D 2 150 ? -45.152 -49.694 -69.868 1.00 80.62 ? 150 PRO D CG 1 +ATOM 10321 C CD . PRO D 2 150 ? -46.341 -49.052 -70.529 1.00 75.27 ? 150 PRO D CD 1 +ATOM 10322 N N . ASP D 2 151 ? -47.418 -49.776 -65.978 1.00 81.68 ? 151 ASP D N 1 +ATOM 10323 C CA . ASP D 2 151 ? -47.945 -49.139 -64.781 1.00 85.63 ? 151 ASP D CA 1 +ATOM 10324 C C . ASP D 2 151 ? -47.372 -47.732 -64.618 1.00 89.21 ? 151 ASP D C 1 +ATOM 10325 O O . ASP D 2 151 ? -46.396 -47.339 -65.265 1.00 91.22 ? 151 ASP D O 1 +ATOM 10326 C CB . ASP D 2 151 ? -47.644 -49.981 -63.542 1.00 85.54 ? 151 ASP D CB 1 +ATOM 10327 C CG . ASP D 2 151 ? -48.496 -51.227 -63.467 1.00 85.17 ? 151 ASP D CG 1 +ATOM 10328 O OD1 . ASP D 2 151 ? -49.601 -51.217 -64.053 1.00 80.31 ? 151 ASP D OD1 1 +ATOM 10329 O OD2 . ASP D 2 151 ? -48.068 -52.207 -62.822 1.00 83.93 ? 151 ASP D OD2 1 +ATOM 10330 N N . LEU D 2 152 ? -47.978 -46.980 -63.707 1.00 89.33 ? 152 LEU D N 1 +ATOM 10331 C CA . LEU D 2 152 ? -47.600 -45.601 -63.464 1.00 81.27 ? 152 LEU D CA 1 +ATOM 10332 C C . LEU D 2 152 ? -47.000 -45.469 -62.072 1.00 83.50 ? 152 LEU D C 1 +ATOM 10333 O O . LEU D 2 152 ? -46.750 -46.459 -61.375 1.00 95.31 ? 152 LEU D O 1 +ATOM 10334 C CB . LEU D 2 152 ? -48.810 -44.682 -63.630 1.00 77.56 ? 152 LEU D CB 1 +ATOM 10335 C CG . LEU D 2 152 ? -49.430 -44.632 -65.023 1.00 73.66 ? 152 LEU D CG 1 +ATOM 10336 C CD1 . LEU D 2 152 ? -50.602 -45.599 -65.127 1.00 66.54 ? 152 LEU D CD1 1 +ATOM 10337 C CD2 . LEU D 2 152 ? -49.859 -43.216 -65.339 1.00 73.72 ? 152 LEU D CD2 1 +ATOM 10338 N N . THR D 2 153 ? -46.798 -44.226 -61.661 1.00 79.97 ? 153 THR D N 1 +ATOM 10339 C CA . THR D 2 153 ? -46.207 -43.869 -60.382 1.00 87.41 ? 153 THR D CA 1 +ATOM 10340 C C . THR D 2 153 ? -46.387 -42.373 -60.217 1.00 95.75 ? 153 THR D C 1 +ATOM 10341 O O . THR D 2 153 ? -46.492 -41.645 -61.208 1.00 97.67 ? 153 THR D O 1 +ATOM 10342 C CB . THR D 2 153 ? -44.718 -44.245 -60.293 1.00 80.63 ? 153 THR D CB 1 +ATOM 10343 O OG1 . THR D 2 153 ? -44.140 -43.653 -59.122 1.00 81.22 ? 153 THR D OG1 1 +ATOM 10344 C CG2 . THR D 2 153 ? -43.955 -43.770 -61.522 1.00 73.51 ? 153 THR D CG2 1 +ATOM 10345 N N . GLU D 2 154 ? -46.481 -41.929 -58.961 1.00 101.25 ? 154 GLU D N 1 +ATOM 10346 C CA . GLU D 2 154 ? -46.645 -40.503 -58.697 1.00 98.79 ? 154 GLU D CA 1 +ATOM 10347 C C . GLU D 2 154 ? -45.587 -39.667 -59.409 1.00 95.27 ? 154 GLU D C 1 +ATOM 10348 O O . GLU D 2 154 ? -45.829 -38.486 -59.692 1.00 90.68 ? 154 GLU D O 1 +ATOM 10349 C CB . GLU D 2 154 ? -46.607 -40.235 -57.191 1.00 102.37 ? 154 GLU D CB 1 +ATOM 10350 C CG . GLU D 2 154 ? -47.813 -39.464 -56.668 1.00 98.52 ? 154 GLU D CG 1 +ATOM 10351 C CD . GLU D 2 154 ? -47.430 -38.405 -55.647 1.00 98.74 ? 154 GLU D CD 1 +ATOM 10352 O OE1 . GLU D 2 154 ? -48.112 -37.358 -55.592 1.00 88.62 ? 154 GLU D OE1 1 +ATOM 10353 O OE2 . GLU D 2 154 ? -46.443 -38.618 -54.907 1.00 94.80 ? 154 GLU D OE2 1 +ATOM 10354 N N . GLU D 2 155 ? -44.426 -40.256 -59.722 1.00 91.65 ? 155 GLU D N 1 +ATOM 10355 C CA . GLU D 2 155 ? -43.423 -39.563 -60.521 1.00 91.57 ? 155 GLU D CA 1 +ATOM 10356 C C . GLU D 2 155 ? -43.826 -39.461 -61.991 1.00 89.61 ? 155 GLU D C 1 +ATOM 10357 O O . GLU D 2 155 ? -43.277 -38.622 -62.713 1.00 90.60 ? 155 GLU D O 1 +ATOM 10358 C CB . GLU D 2 155 ? -42.067 -40.274 -60.391 1.00 83.83 ? 155 GLU D CB 1 +ATOM 10359 C CG . GLU D 2 155 ? -40.856 -39.392 -60.717 1.00 102.34 ? 155 GLU D CG 1 +ATOM 10360 C CD . GLU D 2 155 ? -40.392 -39.516 -62.164 1.00 119.94 ? 155 GLU D CD 1 +ATOM 10361 O OE1 . GLU D 2 155 ? -40.979 -40.331 -62.912 1.00 112.27 ? 155 GLU D OE1 1 +ATOM 10362 O OE2 . GLU D 2 155 ? -39.456 -38.784 -62.557 1.00 115.33 ? 155 GLU D OE2 1 +ATOM 10363 N N . ASP D 2 156 ? -44.783 -40.270 -62.449 1.00 85.46 ? 156 ASP D N 1 +ATOM 10364 C CA . ASP D 2 156 ? -45.226 -40.208 -63.839 1.00 84.34 ? 156 ASP D CA 1 +ATOM 10365 C C . ASP D 2 156 ? -46.448 -39.323 -64.046 1.00 85.17 ? 156 ASP D C 1 +ATOM 10366 O O . ASP D 2 156 ? -46.788 -39.027 -65.199 1.00 73.82 ? 156 ASP D O 1 +ATOM 10367 C CB . ASP D 2 156 ? -45.523 -41.612 -64.375 1.00 87.86 ? 156 ASP D CB 1 +ATOM 10368 C CG . ASP D 2 156 ? -44.264 -42.375 -64.723 1.00 88.38 ? 156 ASP D CG 1 +ATOM 10369 O OD1 . ASP D 2 156 ? -43.238 -41.718 -65.004 1.00 83.32 ? 156 ASP D OD1 1 +ATOM 10370 O OD2 . ASP D 2 156 ? -44.305 -43.626 -64.740 1.00 88.17 ? 156 ASP D OD2 1 +ATOM 10371 N N . THR D 2 157 ? -47.131 -38.927 -62.974 1.00 90.99 ? 157 THR D N 1 +ATOM 10372 C CA . THR D 2 157 ? -48.173 -37.916 -63.081 1.00 84.01 ? 157 THR D CA 1 +ATOM 10373 C C . THR D 2 157 ? -47.544 -36.545 -63.323 1.00 80.01 ? 157 THR D C 1 +ATOM 10374 O O . THR D 2 157 ? -46.364 -36.309 -63.040 1.00 81.06 ? 157 THR D O 1 +ATOM 10375 C CB . THR D 2 157 ? -49.043 -37.887 -61.822 1.00 80.44 ? 157 THR D CB 1 +ATOM 10376 O OG1 . THR D 2 157 ? -48.319 -38.443 -60.714 1.00 81.26 ? 157 THR D OG1 1 +ATOM 10377 C CG2 . THR D 2 157 ? -50.329 -38.671 -62.042 1.00 66.39 ? 157 THR D CG2 1 +ATOM 10378 N N . LEU D 2 158 ? -48.353 -35.621 -63.834 1.00 67.79 ? 158 LEU D N 1 +ATOM 10379 C CA . LEU D 2 158 ? -47.814 -34.304 -64.148 1.00 66.60 ? 158 LEU D CA 1 +ATOM 10380 C C . LEU D 2 158 ? -47.772 -33.399 -62.923 1.00 69.55 ? 158 LEU D C 1 +ATOM 10381 O O . LEU D 2 158 ? -46.743 -32.779 -62.637 1.00 69.47 ? 158 LEU D O 1 +ATOM 10382 C CB . LEU D 2 158 ? -48.634 -33.655 -65.262 1.00 59.17 ? 158 LEU D CB 1 +ATOM 10383 C CG . LEU D 2 158 ? -47.828 -33.197 -66.477 1.00 57.65 ? 158 LEU D CG 1 +ATOM 10384 C CD1 . LEU D 2 158 ? -48.656 -32.232 -67.297 1.00 54.22 ? 158 LEU D CD1 1 +ATOM 10385 C CD2 . LEU D 2 158 ? -46.498 -32.575 -66.069 1.00 58.04 ? 158 LEU D CD2 1 +ATOM 10386 N N . PHE D 2 159 ? -48.879 -33.304 -62.195 1.00 65.24 ? 159 PHE D N 1 +ATOM 10387 C CA . PHE D 2 159 ? -48.960 -32.414 -61.049 1.00 57.92 ? 159 PHE D CA 1 +ATOM 10388 C C . PHE D 2 159 ? -50.089 -32.881 -60.142 1.00 63.18 ? 159 PHE D C 1 +ATOM 10389 O O . PHE D 2 159 ? -51.024 -33.555 -60.583 1.00 62.09 ? 159 PHE D O 1 +ATOM 10390 C CB . PHE D 2 159 ? -49.183 -30.969 -61.499 1.00 54.90 ? 159 PHE D CB 1 +ATOM 10391 C CG . PHE D 2 159 ? -50.261 -30.823 -62.537 1.00 54.83 ? 159 PHE D CG 1 +ATOM 10392 C CD1 . PHE D 2 159 ? -51.596 -30.768 -62.167 1.00 58.79 ? 159 PHE D CD1 1 +ATOM 10393 C CD2 . PHE D 2 159 ? -49.943 -30.740 -63.882 1.00 54.92 ? 159 PHE D CD2 1 +ATOM 10394 C CE1 . PHE D 2 159 ? -52.592 -30.636 -63.117 1.00 57.78 ? 159 PHE D CE1 1 +ATOM 10395 C CE2 . PHE D 2 159 ? -50.939 -30.608 -64.840 1.00 57.65 ? 159 PHE D CE2 1 +ATOM 10396 C CZ . PHE D 2 159 ? -52.264 -30.555 -64.455 1.00 57.02 ? 159 PHE D CZ 1 +ATOM 10397 N N . ASN D 2 160 ? -50.001 -32.499 -58.871 1.00 63.74 ? 160 ASN D N 1 +ATOM 10398 C CA . ASN D 2 160 ? -50.999 -32.890 -57.876 1.00 60.96 ? 160 ASN D CA 1 +ATOM 10399 C C . ASN D 2 160 ? -52.222 -32.005 -58.071 1.00 54.95 ? 160 ASN D C 1 +ATOM 10400 O O . ASN D 2 160 ? -52.282 -30.886 -57.564 1.00 59.68 ? 160 ASN D O 1 +ATOM 10401 C CB . ASN D 2 160 ? -50.443 -32.757 -56.463 1.00 58.99 ? 160 ASN D CB 1 +ATOM 10402 C CG . ASN D 2 160 ? -49.269 -33.678 -56.205 1.00 70.30 ? 160 ASN D CG 1 +ATOM 10403 O OD1 . ASN D 2 160 ? -49.193 -34.778 -56.757 1.00 75.28 ? 160 ASN D OD1 1 +ATOM 10404 N ND2 . ASN D 2 160 ? -48.329 -33.220 -55.383 1.00 69.69 ? 160 ASN D ND2 1 +ATOM 10405 N N . LEU D 2 161 ? -53.183 -32.503 -58.863 1.00 49.60 ? 161 LEU D N 1 +ATOM 10406 C CA . LEU D 2 161 ? -54.505 -31.909 -59.089 1.00 47.31 ? 161 LEU D CA 1 +ATOM 10407 C C . LEU D 2 161 ? -54.926 -30.862 -58.063 1.00 57.58 ? 161 LEU D C 1 +ATOM 10408 O O . LEU D 2 161 ? -55.476 -29.815 -58.426 1.00 57.82 ? 161 LEU D O 1 +ATOM 10409 C CB . LEU D 2 161 ? -55.570 -33.006 -59.119 1.00 44.03 ? 161 LEU D CB 1 +ATOM 10410 C CG . LEU D 2 161 ? -57.018 -32.573 -58.859 1.00 46.06 ? 161 LEU D CG 1 +ATOM 10411 C CD1 . LEU D 2 161 ? -57.561 -31.686 -59.974 1.00 57.02 ? 161 LEU D CD1 1 +ATOM 10412 C CD2 . LEU D 2 161 ? -57.914 -33.790 -58.667 1.00 54.13 ? 161 LEU D CD2 1 +ATOM 10413 N N . ASN D 2 162 ? -54.679 -31.142 -56.780 1.00 69.53 ? 162 ASN D N 1 +ATOM 10414 C CA . ASN D 2 162 ? -54.962 -30.194 -55.710 1.00 68.68 ? 162 ASN D CA 1 +ATOM 10415 C C . ASN D 2 162 ? -54.191 -28.886 -55.866 1.00 59.85 ? 162 ASN D C 1 +ATOM 10416 O O . ASN D 2 162 ? -54.536 -27.898 -55.207 1.00 59.40 ? 162 ASN D O 1 +ATOM 10417 C CB . ASN D 2 162 ? -54.629 -30.859 -54.363 1.00 63.87 ? 162 ASN D CB 1 +ATOM 10418 C CG . ASN D 2 162 ? -55.135 -30.073 -53.170 1.00 71.01 ? 162 ASN D CG 1 +ATOM 10419 O OD1 . ASN D 2 162 ? -56.170 -29.408 -53.242 1.00 78.80 ? 162 ASN D OD1 1 +ATOM 10420 N ND2 . ASN D 2 162 ? -54.424 -30.174 -52.050 1.00 72.20 ? 162 ASN D ND2 1 +ATOM 10421 N N . ALA D 2 163 ? -53.216 -28.828 -56.772 1.00 55.50 ? 163 ALA D N 1 +ATOM 10422 C CA . ALA D 2 163 ? -52.401 -27.643 -56.962 1.00 49.25 ? 163 ALA D CA 1 +ATOM 10423 C C . ALA D 2 163 ? -52.750 -26.880 -58.222 1.00 48.34 ? 163 ALA D C 1 +ATOM 10424 O O . ALA D 2 163 ? -52.276 -25.753 -58.388 1.00 52.52 ? 163 ALA D O 1 +ATOM 10425 C CB . ALA D 2 163 ? -50.908 -28.013 -56.999 1.00 51.59 ? 163 ALA D CB 1 +ATOM 10426 N N . GLU D 2 164 ? -53.564 -27.448 -59.106 1.00 48.27 ? 164 GLU D N 1 +ATOM 10427 C CA . GLU D 2 164 ? -54.080 -26.671 -60.221 1.00 45.62 ? 164 GLU D CA 1 +ATOM 10428 C C . GLU D 2 164 ? -55.389 -25.983 -59.863 1.00 51.63 ? 164 GLU D C 1 +ATOM 10429 O O . GLU D 2 164 ? -55.666 -24.891 -60.370 1.00 54.85 ? 164 GLU D O 1 +ATOM 10430 C CB . GLU D 2 164 ? -54.258 -27.555 -61.463 1.00 47.10 ? 164 GLU D CB 1 +ATOM 10431 C CG . GLU D 2 164 ? -54.798 -26.807 -62.687 1.00 57.79 ? 164 GLU D CG 1 +ATOM 10432 C CD . GLU D 2 164 ? -54.907 -27.670 -63.939 1.00 67.14 ? 164 GLU D CD 1 +ATOM 10433 O OE1 . GLU D 2 164 ? -55.005 -28.907 -63.803 1.00 72.73 ? 164 GLU D OE1 1 +ATOM 10434 O OE2 . GLU D 2 164 ? -54.924 -27.109 -65.059 1.00 61.13 ? 164 GLU D OE2 1 +ATOM 10435 N N . ILE D 2 165 ? -56.184 -26.573 -58.966 1.00 53.25 ? 165 ILE D N 1 +ATOM 10436 C CA . ILE D 2 165 ? -57.367 -25.892 -58.456 1.00 53.07 ? 165 ILE D CA 1 +ATOM 10437 C C . ILE D 2 165 ? -56.989 -24.708 -57.584 1.00 51.94 ? 165 ILE D C 1 +ATOM 10438 O O . ILE D 2 165 ? -57.837 -23.852 -57.304 1.00 48.19 ? 165 ILE D O 1 +ATOM 10439 C CB . ILE D 2 165 ? -58.266 -26.888 -57.691 1.00 54.70 ? 165 ILE D CB 1 +ATOM 10440 C CG1 . ILE D 2 165 ? -57.555 -27.473 -56.455 1.00 62.39 ? 165 ILE D CG1 1 +ATOM 10441 C CG2 . ILE D 2 165 ? -58.731 -28.001 -58.621 1.00 54.22 ? 165 ILE D CG2 1 +ATOM 10442 C CD1 . ILE D 2 165 ? -57.937 -26.834 -55.118 1.00 59.06 ? 165 ILE D CD1 1 +ATOM 10443 N N . ARG D 2 166 ? -55.706 -24.606 -57.217 1.00 50.60 ? 166 ARG D N 1 +ATOM 10444 C CA . ARG D 2 166 ? -55.171 -23.496 -56.442 1.00 49.20 ? 166 ARG D CA 1 +ATOM 10445 C C . ARG D 2 166 ? -54.725 -22.348 -57.324 1.00 52.19 ? 166 ARG D C 1 +ATOM 10446 O O . ARG D 2 166 ? -54.397 -21.276 -56.810 1.00 59.05 ? 166 ARG D O 1 +ATOM 10447 C CB . ARG D 2 166 ? -53.986 -23.978 -55.567 1.00 55.83 ? 166 ARG D CB 1 +ATOM 10448 C CG . ARG D 2 166 ? -53.291 -22.908 -54.710 1.00 55.61 ? 166 ARG D CG 1 +ATOM 10449 C CD . ARG D 2 166 ? -52.103 -23.430 -53.920 1.00 58.88 ? 166 ARG D CD 1 +ATOM 10450 N NE . ARG D 2 166 ? -52.506 -24.491 -53.000 1.00 71.90 ? 166 ARG D NE 1 +ATOM 10451 C CZ . ARG D 2 166 ? -52.175 -25.776 -53.088 1.00 76.62 ? 166 ARG D CZ 1 +ATOM 10452 N NH1 . ARG D 2 166 ? -51.398 -26.211 -54.072 1.00 76.58 ? 166 ARG D NH1 1 +ATOM 10453 N NH2 . ARG D 2 166 ? -52.622 -26.626 -52.165 1.00 82.04 ? 166 ARG D NH2 1 +ATOM 10454 N N . LEU D 2 167 ? -54.765 -22.509 -58.639 1.00 47.93 ? 167 LEU D N 1 +ATOM 10455 C CA . LEU D 2 167 ? -54.423 -21.395 -59.503 1.00 42.25 ? 167 LEU D CA 1 +ATOM 10456 C C . LEU D 2 167 ? -55.641 -20.653 -60.026 1.00 45.81 ? 167 LEU D C 1 +ATOM 10457 O O . LEU D 2 167 ? -55.516 -19.483 -60.402 1.00 49.54 ? 167 LEU D O 1 +ATOM 10458 C CB . LEU D 2 167 ? -53.573 -21.873 -60.683 1.00 38.00 ? 167 LEU D CB 1 +ATOM 10459 C CG . LEU D 2 167 ? -52.063 -21.814 -60.455 1.00 38.00 ? 167 LEU D CG 1 +ATOM 10460 C CD1 . LEU D 2 167 ? -51.649 -22.694 -59.302 1.00 42.25 ? 167 LEU D CD1 1 +ATOM 10461 C CD2 . LEU D 2 167 ? -51.314 -22.211 -61.711 1.00 45.05 ? 167 LEU D CD2 1 +ATOM 10462 N N . TYR D 2 168 ? -56.804 -21.267 -60.002 1.00 43.52 ? 168 TYR D N 1 +ATOM 10463 C CA . TYR D 2 168 ? -58.023 -20.681 -60.529 1.00 49.78 ? 168 TYR D CA 1 +ATOM 10464 C C . TYR D 2 168 ? -58.823 -20.020 -59.417 1.00 53.43 ? 168 TYR D C 1 +ATOM 10465 O O . TYR D 2 168 ? -58.604 -20.302 -58.236 1.00 55.11 ? 168 TYR D O 1 +ATOM 10466 C CB . TYR D 2 168 ? -58.857 -21.764 -61.231 1.00 57.96 ? 168 TYR D CB 1 +ATOM 10467 C CG . TYR D 2 168 ? -58.350 -22.152 -62.616 1.00 54.43 ? 168 TYR D CG 1 +ATOM 10468 C CD1 . TYR D 2 168 ? -57.138 -22.818 -62.789 1.00 45.67 ? 168 TYR D CD1 1 +ATOM 10469 C CD2 . TYR D 2 168 ? -59.091 -21.841 -63.752 1.00 56.19 ? 168 TYR D CD2 1 +ATOM 10470 C CE1 . TYR D 2 168 ? -56.682 -23.160 -64.055 1.00 41.21 ? 168 TYR D CE1 1 +ATOM 10471 C CE2 . TYR D 2 168 ? -58.640 -22.176 -65.018 1.00 55.52 ? 168 TYR D CE2 1 +ATOM 10472 C CZ . TYR D 2 168 ? -57.436 -22.835 -65.164 1.00 52.61 ? 168 TYR D CZ 1 +ATOM 10473 O OH . TYR D 2 168 ? -56.994 -23.172 -66.425 1.00 54.56 ? 168 TYR D OH 1 +ATOM 10474 N N . PRO D 2 169 ? -59.755 -19.096 -59.757 1.00 59.10 ? 169 PRO D N 1 +ATOM 10475 C CA . PRO D 2 169 ? -60.543 -18.417 -58.716 1.00 66.49 ? 169 PRO D CA 1 +ATOM 10476 C C . PRO D 2 169 ? -61.390 -19.365 -57.883 1.00 68.58 ? 169 PRO D C 1 +ATOM 10477 O O . PRO D 2 169 ? -61.454 -20.566 -58.161 1.00 70.92 ? 169 PRO D O 1 +ATOM 10478 C CB . PRO D 2 169 ? -61.428 -17.452 -59.520 1.00 69.00 ? 169 PRO D CB 1 +ATOM 10479 C CG . PRO D 2 169 ? -61.452 -18.008 -60.901 1.00 63.30 ? 169 PRO D CG 1 +ATOM 10480 C CD . PRO D 2 169 ? -60.098 -18.603 -61.101 1.00 58.08 ? 169 PRO D CD 1 +ATOM 10481 N N . LYS D 2 170 ? -62.071 -18.826 -56.870 1.00 69.78 ? 170 LYS D N 1 +ATOM 10482 C CA . LYS D 2 170 ? -62.907 -19.627 -55.982 1.00 76.78 ? 170 LYS D CA 1 +ATOM 10483 C C . LYS D 2 170 ? -64.121 -20.239 -56.687 1.00 86.54 ? 170 LYS D C 1 +ATOM 10484 O O . LYS D 2 170 ? -64.871 -20.984 -56.041 1.00 85.76 ? 170 LYS D O 1 +ATOM 10485 C CB . LYS D 2 170 ? -63.355 -18.769 -54.796 1.00 74.46 ? 170 LYS D CB 1 +ATOM 10486 C CG . LYS D 2 170 ? -62.199 -18.246 -53.950 1.00 72.10 ? 170 LYS D CG 1 +ATOM 10487 C CD . LYS D 2 170 ? -62.664 -17.859 -52.554 1.00 74.87 ? 170 LYS D CD 1 +ATOM 10488 C CE . LYS D 2 170 ? -62.968 -19.092 -51.704 1.00 83.02 ? 170 LYS D CE 1 +ATOM 10489 N NZ . LYS D 2 170 ? -61.800 -20.009 -51.550 1.00 79.89 ? 170 LYS D NZ 1 +ATOM 10490 N N . ALA D 2 171 ? -64.325 -19.937 -57.972 1.00 82.66 ? 171 ALA D N 1 +ATOM 10491 C CA . ALA D 2 171 ? -65.381 -20.533 -58.792 1.00 76.31 ? 171 ALA D CA 1 +ATOM 10492 C C . ALA D 2 171 ? -66.757 -20.182 -58.245 1.00 85.49 ? 171 ALA D C 1 +ATOM 10493 O O . ALA D 2 171 ? -66.983 -19.059 -57.797 1.00 85.72 ? 171 ALA D O 1 +ATOM 10494 C CB . ALA D 2 171 ? -65.210 -22.048 -58.887 1.00 82.61 ? 171 ALA D CB 1 +ATOM 10495 N N . GLU D 2 197 ? -65.957 -36.299 -59.134 1.00 104.46 ? 197 GLU D N 1 +ATOM 10496 C CA . GLU D 2 197 ? -65.445 -36.000 -60.469 1.00 113.44 ? 197 GLU D CA 1 +ATOM 10497 C C . GLU D 2 197 ? -66.405 -35.126 -61.272 1.00 114.54 ? 197 GLU D C 1 +ATOM 10498 O O . GLU D 2 197 ? -66.688 -35.408 -62.439 1.00 110.20 ? 197 GLU D O 1 +ATOM 10499 C CB . GLU D 2 197 ? -65.157 -37.295 -61.236 1.00 103.88 ? 197 GLU D CB 1 +ATOM 10500 C CG . GLU D 2 197 ? -63.911 -38.011 -60.755 1.00 103.78 ? 197 GLU D CG 1 +ATOM 10501 C CD . GLU D 2 197 ? -62.729 -37.068 -60.620 1.00 113.48 ? 197 GLU D CD 1 +ATOM 10502 O OE1 . GLU D 2 197 ? -62.379 -36.396 -61.615 1.00 107.14 ? 197 GLU D OE1 1 +ATOM 10503 O OE2 . GLU D 2 197 ? -62.161 -36.987 -59.510 1.00 117.66 ? 197 GLU D OE2 1 +ATOM 10504 N N . SER D 2 198 ? -66.903 -34.063 -60.642 1.00 107.37 ? 198 SER D N 1 +ATOM 10505 C CA . SER D 2 198 ? -67.742 -33.084 -61.315 1.00 101.47 ? 198 SER D CA 1 +ATOM 10506 C C . SER D 2 198 ? -66.934 -31.921 -61.876 1.00 94.14 ? 198 SER D C 1 +ATOM 10507 O O . SER D 2 198 ? -67.514 -30.897 -62.250 1.00 92.42 ? 198 SER D O 1 +ATOM 10508 C CB . SER D 2 198 ? -68.820 -32.568 -60.359 1.00 93.37 ? 198 SER D CB 1 +ATOM 10509 O OG . SER D 2 198 ? -69.617 -31.576 -60.978 1.00 102.09 ? 198 SER D OG 1 +ATOM 10510 N N . TYR D 2 199 ? -65.611 -32.059 -61.931 1.00 84.17 ? 199 TYR D N 1 +ATOM 10511 C CA . TYR D 2 199 ? -64.756 -31.037 -62.509 1.00 78.47 ? 199 TYR D CA 1 +ATOM 10512 C C . TYR D 2 199 ? -64.983 -30.921 -64.017 1.00 82.75 ? 199 TYR D C 1 +ATOM 10513 O O . TYR D 2 199 ? -65.321 -31.905 -64.682 1.00 87.95 ? 199 TYR D O 1 +ATOM 10514 C CB . TYR D 2 199 ? -63.295 -31.361 -62.243 1.00 72.92 ? 199 TYR D CB 1 +ATOM 10515 C CG . TYR D 2 199 ? -62.964 -31.517 -60.786 1.00 76.22 ? 199 TYR D CG 1 +ATOM 10516 C CD1 . TYR D 2 199 ? -63.657 -30.804 -59.818 1.00 80.41 ? 199 TYR D CD1 1 +ATOM 10517 C CD2 . TYR D 2 199 ? -61.948 -32.368 -60.378 1.00 85.58 ? 199 TYR D CD2 1 +ATOM 10518 C CE1 . TYR D 2 199 ? -63.349 -30.942 -58.479 1.00 94.00 ? 199 TYR D CE1 1 +ATOM 10519 C CE2 . TYR D 2 199 ? -61.630 -32.512 -59.044 1.00 86.27 ? 199 TYR D CE2 1 +ATOM 10520 C CZ . TYR D 2 199 ? -62.333 -31.797 -58.098 1.00 90.87 ? 199 TYR D CZ 1 +ATOM 10521 O OH . TYR D 2 199 ? -62.020 -31.944 -56.766 1.00 88.12 ? 199 TYR D OH 1 +ATOM 10522 N N . PRO D 2 200 ? -64.817 -29.722 -64.576 1.00 67.30 ? 200 PRO D N 1 +ATOM 10523 C CA . PRO D 2 200 ? -65.006 -29.549 -66.019 1.00 61.70 ? 200 PRO D CA 1 +ATOM 10524 C C . PRO D 2 200 ? -64.073 -30.444 -66.825 1.00 67.84 ? 200 PRO D C 1 +ATOM 10525 O O . PRO D 2 200 ? -63.040 -30.918 -66.342 1.00 59.57 ? 200 PRO D O 1 +ATOM 10526 C CB . PRO D 2 200 ? -64.696 -28.066 -66.240 1.00 62.40 ? 200 PRO D CB 1 +ATOM 10527 C CG . PRO D 2 200 ? -64.984 -27.426 -64.922 1.00 64.89 ? 200 PRO D CG 1 +ATOM 10528 C CD . PRO D 2 200 ? -64.549 -28.440 -63.901 1.00 64.74 ? 200 PRO D CD 1 +ATOM 10529 N N . ASN D 2 201 ? -64.479 -30.693 -68.076 1.00 73.39 ? 201 ASN D N 1 +ATOM 10530 C CA . ASN D 2 201 ? -63.758 -31.615 -68.949 1.00 58.59 ? 201 ASN D CA 1 +ATOM 10531 C C . ASN D 2 201 ? -62.328 -31.165 -69.216 1.00 53.39 ? 201 ASN D C 1 +ATOM 10532 O O . ASN D 2 201 ? -61.439 -32.009 -69.386 1.00 53.39 ? 201 ASN D O 1 +ATOM 10533 C CB . ASN D 2 201 ? -64.505 -31.771 -70.271 1.00 55.38 ? 201 ASN D CB 1 +ATOM 10534 C CG . ASN D 2 201 ? -65.888 -32.357 -70.091 1.00 61.61 ? 201 ASN D CG 1 +ATOM 10535 O OD1 . ASN D 2 201 ? -66.162 -33.045 -69.104 1.00 63.65 ? 201 ASN D OD1 1 +ATOM 10536 N ND2 . ASN D 2 201 ? -66.771 -32.088 -71.046 1.00 62.98 ? 201 ASN D ND2 1 +ATOM 10537 N N . TRP D 2 202 ? -62.083 -29.852 -69.288 1.00 51.47 ? 202 TRP D N 1 +ATOM 10538 C CA . TRP D 2 202 ? -60.720 -29.380 -69.505 1.00 52.01 ? 202 TRP D CA 1 +ATOM 10539 C C . TRP D 2 202 ? -59.815 -29.674 -68.319 1.00 51.94 ? 202 TRP D C 1 +ATOM 10540 O O . TRP D 2 202 ? -58.589 -29.671 -68.470 1.00 48.33 ? 202 TRP D O 1 +ATOM 10541 C CB . TRP D 2 202 ? -60.706 -27.877 -69.804 1.00 47.60 ? 202 TRP D CB 1 +ATOM 10542 C CG . TRP D 2 202 ? -61.147 -27.017 -68.667 1.00 52.59 ? 202 TRP D CG 1 +ATOM 10543 C CD1 . TRP D 2 202 ? -62.396 -26.517 -68.458 1.00 57.37 ? 202 TRP D CD1 1 +ATOM 10544 C CD2 . TRP D 2 202 ? -60.341 -26.552 -67.576 1.00 56.13 ? 202 TRP D CD2 1 +ATOM 10545 N NE1 . TRP D 2 202 ? -62.423 -25.766 -67.307 1.00 54.92 ? 202 TRP D NE1 1 +ATOM 10546 C CE2 . TRP D 2 202 ? -61.173 -25.774 -66.745 1.00 54.09 ? 202 TRP D CE2 1 +ATOM 10547 C CE3 . TRP D 2 202 ? -58.999 -26.718 -67.220 1.00 56.53 ? 202 TRP D CE3 1 +ATOM 10548 C CZ2 . TRP D 2 202 ? -60.706 -25.165 -65.585 1.00 51.69 ? 202 TRP D CZ2 1 +ATOM 10549 C CZ3 . TRP D 2 202 ? -58.539 -26.115 -66.066 1.00 51.15 ? 202 TRP D CZ3 1 +ATOM 10550 C CH2 . TRP D 2 202 ? -59.391 -25.353 -65.262 1.00 52.04 ? 202 TRP D CH2 1 +ATOM 10551 N N . LEU D 2 203 ? -60.387 -29.947 -67.149 1.00 56.29 ? 203 LEU D N 1 +ATOM 10552 C CA . LEU D 2 203 ? -59.580 -30.294 -65.990 1.00 56.19 ? 203 LEU D CA 1 +ATOM 10553 C C . LEU D 2 203 ? -59.285 -31.787 -65.965 1.00 57.41 ? 203 LEU D C 1 +ATOM 10554 O O . LEU D 2 203 ? -58.134 -32.188 -65.766 1.00 55.47 ? 203 LEU D O 1 +ATOM 10555 C CB . LEU D 2 203 ? -60.287 -29.857 -64.701 1.00 55.13 ? 203 LEU D CB 1 +ATOM 10556 C CG . LEU D 2 203 ? -59.526 -30.009 -63.377 1.00 55.07 ? 203 LEU D CG 1 +ATOM 10557 C CD1 . LEU D 2 203 ? -58.059 -29.648 -63.520 1.00 50.82 ? 203 LEU D CD1 1 +ATOM 10558 C CD2 . LEU D 2 203 ? -60.169 -29.162 -62.294 1.00 58.23 ? 203 LEU D CD2 1 +ATOM 10559 N N . ARG D 2 204 ? -60.309 -32.618 -66.196 1.00 59.24 ? 204 ARG D N 1 +ATOM 10560 C CA . ARG D 2 204 ? -60.078 -34.050 -66.360 1.00 62.37 ? 204 ARG D CA 1 +ATOM 10561 C C . ARG D 2 204 ? -59.084 -34.316 -67.485 1.00 60.52 ? 204 ARG D C 1 +ATOM 10562 O O . ARG D 2 204 ? -58.321 -35.288 -67.428 1.00 55.76 ? 204 ARG D O 1 +ATOM 10563 C CB . ARG D 2 204 ? -61.403 -34.773 -66.628 1.00 64.63 ? 204 ARG D CB 1 +ATOM 10564 C CG . ARG D 2 204 ? -61.555 -36.126 -65.921 1.00 75.75 ? 204 ARG D CG 1 +ATOM 10565 C CD . ARG D 2 204 ? -62.534 -36.037 -64.751 1.00 89.27 ? 204 ARG D CD 1 +ATOM 10566 N NE . ARG D 2 204 ? -63.794 -35.407 -65.143 1.00 99.14 ? 204 ARG D NE 1 +ATOM 10567 C CZ . ARG D 2 204 ? -64.909 -36.067 -65.446 1.00 100.62 ? 204 ARG D CZ 1 +ATOM 10568 N NH1 . ARG D 2 204 ? -65.999 -35.396 -65.799 1.00 98.90 ? 204 ARG D NH1 1 +ATOM 10569 N NH2 . ARG D 2 204 ? -64.940 -37.393 -65.391 1.00 90.45 ? 204 ARG D NH2 1 +ATOM 10570 N N . PHE D 2 205 ? -59.073 -33.456 -68.505 1.00 56.03 ? 205 PHE D N 1 +ATOM 10571 C CA . PHE D 2 205 ? -58.079 -33.564 -69.564 1.00 51.93 ? 205 PHE D CA 1 +ATOM 10572 C C . PHE D 2 205 ? -56.683 -33.240 -69.045 1.00 53.17 ? 205 PHE D C 1 +ATOM 10573 O O . PHE D 2 205 ? -55.708 -33.908 -69.409 1.00 53.15 ? 205 PHE D O 1 +ATOM 10574 C CB . PHE D 2 205 ? -58.471 -32.646 -70.724 1.00 51.49 ? 205 PHE D CB 1 +ATOM 10575 C CG . PHE D 2 205 ? -57.344 -32.322 -71.664 1.00 53.14 ? 205 PHE D CG 1 +ATOM 10576 C CD1 . PHE D 2 205 ? -56.682 -33.323 -72.352 1.00 54.01 ? 205 PHE D CD1 1 +ATOM 10577 C CD2 . PHE D 2 205 ? -56.967 -31.009 -71.880 1.00 52.73 ? 205 PHE D CD2 1 +ATOM 10578 C CE1 . PHE D 2 205 ? -55.652 -33.022 -73.218 1.00 52.04 ? 205 PHE D CE1 1 +ATOM 10579 C CE2 . PHE D 2 205 ? -55.942 -30.702 -72.748 1.00 50.56 ? 205 PHE D CE2 1 +ATOM 10580 C CZ . PHE D 2 205 ? -55.282 -31.710 -73.417 1.00 48.44 ? 205 PHE D CZ 1 +ATOM 10581 N N . HIS D 2 206 ? -56.566 -32.227 -68.185 1.00 54.39 ? 206 HIS D N 1 +ATOM 10582 C CA . HIS D 2 206 ? -55.245 -31.818 -67.715 1.00 62.86 ? 206 HIS D CA 1 +ATOM 10583 C C . HIS D 2 206 ? -54.629 -32.858 -66.783 1.00 59.71 ? 206 HIS D C 1 +ATOM 10584 O O . HIS D 2 206 ? -53.449 -33.203 -66.925 1.00 58.63 ? 206 HIS D O 1 +ATOM 10585 C CB . HIS D 2 206 ? -55.330 -30.454 -67.023 1.00 65.51 ? 206 HIS D CB 1 +ATOM 10586 C CG . HIS D 2 206 ? -55.370 -29.293 -67.971 1.00 62.51 ? 206 HIS D CG 1 +ATOM 10587 N ND1 . HIS D 2 206 ? -56.279 -28.264 -67.852 1.00 65.75 ? 206 HIS D ND1 1 +ATOM 10588 C CD2 . HIS D 2 206 ? -54.600 -28.988 -69.043 1.00 57.28 ? 206 HIS D CD2 1 +ATOM 10589 C CE1 . HIS D 2 206 ? -56.079 -27.385 -68.819 1.00 62.59 ? 206 HIS D CE1 1 +ATOM 10590 N NE2 . HIS D 2 206 ? -55.062 -27.799 -69.553 1.00 56.66 ? 206 HIS D NE2 1 +ATOM 10591 N N . ILE D 2 207 ? -55.408 -33.380 -65.832 1.00 55.95 ? 207 ILE D N 1 +ATOM 10592 C CA . ILE D 2 207 ? -54.854 -34.307 -64.854 1.00 55.34 ? 207 ILE D CA 1 +ATOM 10593 C C . ILE D 2 207 ? -54.480 -35.641 -65.483 1.00 56.03 ? 207 ILE D C 1 +ATOM 10594 O O . ILE D 2 207 ? -53.637 -36.364 -64.938 1.00 52.34 ? 207 ILE D O 1 +ATOM 10595 C CB . ILE D 2 207 ? -55.845 -34.510 -63.696 1.00 52.01 ? 207 ILE D CB 1 +ATOM 10596 C CG1 . ILE D 2 207 ? -57.200 -34.977 -64.228 1.00 55.20 ? 207 ILE D CG1 1 +ATOM 10597 C CG2 . ILE D 2 207 ? -56.007 -33.221 -62.922 1.00 53.19 ? 207 ILE D CG2 1 +ATOM 10598 C CD1 . ILE D 2 207 ? -58.264 -35.140 -63.155 1.00 52.29 ? 207 ILE D CD1 1 +ATOM 10599 N N . GLY D 2 208 ? -55.071 -35.981 -66.629 1.00 56.09 ? 208 GLY D N 1 +ATOM 10600 C CA . GLY D 2 208 ? -54.778 -37.242 -67.286 1.00 56.82 ? 208 GLY D CA 1 +ATOM 10601 C C . GLY D 2 208 ? -53.515 -37.263 -68.109 1.00 51.45 ? 208 GLY D C 1 +ATOM 10602 O O . GLY D 2 208 ? -53.132 -38.329 -68.598 1.00 51.33 ? 208 GLY D O 1 +ATOM 10603 N N . ILE D 2 209 ? -52.847 -36.123 -68.254 1.00 52.26 ? 209 ILE D N 1 +ATOM 10604 C CA . ILE D 2 209 ? -51.603 -36.043 -69.014 1.00 57.43 ? 209 ILE D CA 1 +ATOM 10605 C C . ILE D 2 209 ? -50.493 -36.713 -68.219 1.00 58.68 ? 209 ILE D C 1 +ATOM 10606 O O . ILE D 2 209 ? -49.935 -36.122 -67.288 1.00 63.36 ? 209 ILE D O 1 +ATOM 10607 C CB . ILE D 2 209 ? -51.249 -34.584 -69.348 1.00 57.75 ? 209 ILE D CB 1 +ATOM 10608 C CG1 . ILE D 2 209 ? -52.459 -33.872 -69.955 1.00 53.87 ? 209 ILE D CG1 1 +ATOM 10609 C CG2 . ILE D 2 209 ? -50.037 -34.527 -70.278 1.00 47.67 ? 209 ILE D CG2 1 +ATOM 10610 C CD1 . ILE D 2 209 ? -52.233 -32.406 -70.210 1.00 51.62 ? 209 ILE D CD1 1 +ATOM 10611 N N . ASN D 2 210 ? -50.193 -37.965 -68.553 1.00 61.95 ? 210 ASN D N 1 +ATOM 10612 C CA . ASN D 2 210 ? -49.131 -38.717 -67.909 1.00 61.31 ? 210 ASN D CA 1 +ATOM 10613 C C . ASN D 2 210 ? -47.890 -38.760 -68.805 1.00 60.36 ? 210 ASN D C 1 +ATOM 10614 O O . ASN D 2 210 ? -47.830 -38.124 -69.862 1.00 55.64 ? 210 ASN D O 1 +ATOM 10615 C CB . ASN D 2 210 ? -49.620 -40.123 -67.568 1.00 61.78 ? 210 ASN D CB 1 +ATOM 10616 C CG . ASN D 2 210 ? -49.906 -40.957 -68.807 1.00 67.82 ? 210 ASN D CG 1 +ATOM 10617 O OD1 . ASN D 2 210 ? -50.556 -40.502 -69.743 1.00 69.33 ? 210 ASN D OD1 1 +ATOM 10618 N ND2 . ASN D 2 210 ? -49.400 -42.184 -68.822 1.00 69.17 ? 210 ASN D ND2 1 +ATOM 10619 N N . ARG D 2 211 ? -46.906 -39.564 -68.389 1.00 60.75 ? 211 ARG D N 1 +ATOM 10620 C CA . ARG D 2 211 ? -45.609 -39.615 -69.060 1.00 55.95 ? 211 ARG D CA 1 +ATOM 10621 C C . ARG D 2 211 ? -45.725 -40.074 -70.508 1.00 52.01 ? 211 ARG D C 1 +ATOM 10622 O O . ARG D 2 211 ? -45.007 -39.573 -71.381 1.00 54.12 ? 211 ARG D O 1 +ATOM 10623 C CB . ARG D 2 211 ? -44.675 -40.544 -68.285 1.00 64.73 ? 211 ARG D CB 1 +ATOM 10624 C CG . ARG D 2 211 ? -43.469 -41.020 -69.067 1.00 60.76 ? 211 ARG D CG 1 +ATOM 10625 C CD . ARG D 2 211 ? -42.488 -41.727 -68.159 1.00 70.02 ? 211 ARG D CD 1 +ATOM 10626 N NE . ARG D 2 211 ? -42.059 -40.877 -67.049 1.00 77.59 ? 211 ARG D NE 1 +ATOM 10627 C CZ . ARG D 2 211 ? -40.952 -40.141 -67.049 1.00 77.49 ? 211 ARG D CZ 1 +ATOM 10628 N NH1 . ARG D 2 211 ? -40.151 -40.150 -68.109 1.00 71.44 ? 211 ARG D NH1 1 +ATOM 10629 N NH2 . ARG D 2 211 ? -40.646 -39.401 -65.987 1.00 70.36 ? 211 ARG D NH2 1 +ATOM 10630 N N . TYR D 2 212 ? -46.584 -41.055 -70.776 1.00 56.86 ? 212 TYR D N 1 +ATOM 10631 C CA . TYR D 2 212 ? -46.645 -41.683 -72.092 1.00 59.72 ? 212 TYR D CA 1 +ATOM 10632 C C . TYR D 2 212 ? -47.656 -41.001 -73.004 1.00 57.07 ? 212 TYR D C 1 +ATOM 10633 O O . TYR D 2 212 ? -47.281 -40.269 -73.925 1.00 51.25 ? 212 TYR D O 1 +ATOM 10634 C CB . TYR D 2 212 ? -46.965 -43.172 -71.953 1.00 62.95 ? 212 TYR D CB 1 +ATOM 10635 C CG . TYR D 2 212 ? -46.059 -43.890 -70.981 1.00 67.60 ? 212 TYR D CG 1 +ATOM 10636 C CD1 . TYR D 2 212 ? -44.743 -44.190 -71.320 1.00 65.28 ? 212 TYR D CD1 1 +ATOM 10637 C CD2 . TYR D 2 212 ? -46.512 -44.260 -69.720 1.00 69.01 ? 212 TYR D CD2 1 +ATOM 10638 C CE1 . TYR D 2 212 ? -43.905 -44.842 -70.430 1.00 72.04 ? 212 TYR D CE1 1 +ATOM 10639 C CE2 . TYR D 2 212 ? -45.681 -44.914 -68.821 1.00 72.47 ? 212 TYR D CE2 1 +ATOM 10640 C CZ . TYR D 2 212 ? -44.378 -45.202 -69.182 1.00 77.67 ? 212 TYR D CZ 1 +ATOM 10641 O OH . TYR D 2 212 ? -43.547 -45.852 -68.294 1.00 75.92 ? 212 TYR D OH 1 +ATOM 10642 N N . GLU D 2 213 ? -48.935 -41.279 -72.797 1.00 64.49 ? 213 GLU D N 1 +ATOM 10643 C CA . GLU D 2 213 ? -49.961 -40.660 -73.613 1.00 66.14 ? 213 GLU D CA 1 +ATOM 10644 C C . GLU D 2 213 ? -50.300 -39.274 -73.069 1.00 62.64 ? 213 GLU D C 1 +ATOM 10645 O O . GLU D 2 213 ? -49.979 -38.927 -71.927 1.00 57.62 ? 213 GLU D O 1 +ATOM 10646 C CB . GLU D 2 213 ? -51.212 -41.538 -73.656 1.00 67.63 ? 213 GLU D CB 1 +ATOM 10647 C CG . GLU D 2 213 ? -51.990 -41.570 -72.345 1.00 71.05 ? 213 GLU D CG 1 +ATOM 10648 C CD . GLU D 2 213 ? -52.956 -42.736 -72.254 1.00 78.86 ? 213 GLU D CD 1 +ATOM 10649 O OE1 . GLU D 2 213 ? -53.332 -43.288 -73.311 1.00 83.66 ? 213 GLU D OE1 1 +ATOM 10650 O OE2 . GLU D 2 213 ? -53.367 -43.078 -71.123 1.00 69.22 ? 213 GLU D OE2 1 +ATOM 10651 N N . LEU D 2 214 ? -50.892 -38.450 -73.934 1.00 57.48 ? 214 LEU D N 1 +ATOM 10652 C CA . LEU D 2 214 ? -51.482 -37.195 -73.493 1.00 51.98 ? 214 LEU D CA 1 +ATOM 10653 C C . LEU D 2 214 ? -52.918 -37.380 -73.014 1.00 55.51 ? 214 LEU D C 1 +ATOM 10654 O O . LEU D 2 214 ? -53.452 -36.497 -72.332 1.00 53.45 ? 214 LEU D O 1 +ATOM 10655 C CB . LEU D 2 214 ? -51.435 -36.158 -74.621 1.00 51.54 ? 214 LEU D CB 1 +ATOM 10656 C CG . LEU D 2 214 ? -51.729 -34.696 -74.268 1.00 51.16 ? 214 LEU D CG 1 +ATOM 10657 C CD1 . LEU D 2 214 ? -50.441 -33.924 -74.108 1.00 48.91 ? 214 LEU D CD1 1 +ATOM 10658 C CD2 . LEU D 2 214 ? -52.615 -34.020 -75.293 1.00 53.90 ? 214 LEU D CD2 1 +ATOM 10659 N N . TYR D 2 215 ? -53.544 -38.508 -73.349 1.00 62.09 ? 215 TYR D N 1 +ATOM 10660 C CA . TYR D 2 215 ? -54.912 -38.822 -72.950 1.00 68.40 ? 215 TYR D CA 1 +ATOM 10661 C C . TYR D 2 215 ? -55.173 -40.294 -73.240 1.00 68.19 ? 215 TYR D C 1 +ATOM 10662 O O . TYR D 2 215 ? -54.646 -40.844 -74.211 1.00 66.65 ? 215 TYR D O 1 +ATOM 10663 C CB . TYR D 2 215 ? -55.924 -37.938 -73.691 1.00 63.68 ? 215 TYR D CB 1 +ATOM 10664 C CG . TYR D 2 215 ? -55.761 -37.940 -75.199 1.00 64.74 ? 215 TYR D CG 1 +ATOM 10665 C CD1 . TYR D 2 215 ? -54.883 -37.061 -75.822 1.00 65.46 ? 215 TYR D CD1 1 +ATOM 10666 C CD2 . TYR D 2 215 ? -56.496 -38.806 -76.003 1.00 67.41 ? 215 TYR D CD2 1 +ATOM 10667 C CE1 . TYR D 2 215 ? -54.727 -37.054 -77.202 1.00 68.33 ? 215 TYR D CE1 1 +ATOM 10668 C CE2 . TYR D 2 215 ? -56.351 -38.801 -77.388 1.00 70.61 ? 215 TYR D CE2 1 +ATOM 10669 C CZ . TYR D 2 215 ? -55.461 -37.923 -77.980 1.00 68.00 ? 215 TYR D CZ 1 +ATOM 10670 O OH . TYR D 2 215 ? -55.298 -37.905 -79.349 1.00 57.74 ? 215 TYR D OH 1 +ATOM 10671 N N . SER D 2 216 ? -55.976 -40.925 -72.378 1.00 64.66 ? 216 SER D N 1 +ATOM 10672 C CA . SER D 2 216 ? -56.284 -42.344 -72.522 1.00 69.46 ? 216 SER D CA 1 +ATOM 10673 C C . SER D 2 216 ? -56.918 -42.634 -73.885 1.00 68.69 ? 216 SER D C 1 +ATOM 10674 O O . SER D 2 216 ? -57.496 -41.757 -74.532 1.00 68.86 ? 216 SER D O 1 +ATOM 10675 C CB . SER D 2 216 ? -57.202 -42.808 -71.393 1.00 68.76 ? 216 SER D CB 1 +ATOM 10676 O OG . SER D 2 216 ? -58.551 -42.490 -71.667 1.00 70.94 ? 216 SER D OG 1 +ATOM 10677 N N . ARG D 2 217 ? -56.814 -43.898 -74.311 1.00 65.50 ? 217 ARG D N 1 +ATOM 10678 C CA . ARG D 2 217 ? -57.225 -44.289 -75.662 1.00 70.21 ? 217 ARG D CA 1 +ATOM 10679 C C . ARG D 2 217 ? -58.688 -43.950 -75.925 1.00 68.90 ? 217 ARG D C 1 +ATOM 10680 O O . ARG D 2 217 ? -59.014 -43.190 -76.845 1.00 69.86 ? 217 ARG D O 1 +ATOM 10681 C CB . ARG D 2 217 ? -56.972 -45.784 -75.874 1.00 74.50 ? 217 ARG D CB 1 +ATOM 10682 C CG . ARG D 2 217 ? -55.942 -46.085 -76.953 1.00 66.44 ? 217 ARG D CG 1 +ATOM 10683 C CD . ARG D 2 217 ? -55.267 -47.427 -76.721 1.00 70.02 ? 217 ARG D CD 1 +ATOM 10684 N NE . ARG D 2 217 ? -53.887 -47.443 -77.208 1.00 86.59 ? 217 ARG D NE 1 +ATOM 10685 C CZ . ARG D 2 217 ? -53.058 -48.479 -77.093 1.00 83.89 ? 217 ARG D CZ 1 +ATOM 10686 N NH1 . ARG D 2 217 ? -53.472 -49.592 -76.509 1.00 78.80 ? 217 ARG D NH1 1 +ATOM 10687 N NH2 . ARG D 2 217 ? -51.817 -48.400 -77.565 1.00 72.22 ? 217 ARG D NH2 1 +ATOM 10688 N N . HIS D 2 218 ? -59.586 -44.505 -75.129 1.00 63.48 ? 218 HIS D N 1 +ATOM 10689 C CA . HIS D 2 218 ? -61.012 -44.267 -75.290 1.00 77.58 ? 218 HIS D CA 1 +ATOM 10690 C C . HIS D 2 218 ? -61.517 -43.558 -74.035 1.00 82.51 ? 218 HIS D C 1 +ATOM 10691 O O . HIS D 2 218 ? -62.279 -44.119 -73.246 1.00 87.29 ? 218 HIS D O 1 +ATOM 10692 C CB . HIS D 2 218 ? -61.759 -45.590 -75.561 1.00 86.14 ? 218 HIS D CB 1 +ATOM 10693 C CG . HIS D 2 218 ? -62.942 -45.443 -76.471 1.00 98.82 ? 218 HIS D CG 1 +ATOM 10694 N ND1 . HIS D 2 218 ? -63.963 -44.547 -76.228 1.00 99.65 ? 218 HIS D ND1 1 +ATOM 10695 C CD2 . HIS D 2 218 ? -63.272 -46.085 -77.617 1.00 93.31 ? 218 HIS D CD2 1 +ATOM 10696 C CE1 . HIS D 2 218 ? -64.867 -44.639 -77.188 1.00 91.22 ? 218 HIS D CE1 1 +ATOM 10697 N NE2 . HIS D 2 218 ? -64.472 -45.566 -78.043 1.00 95.14 ? 218 HIS D NE2 1 +ATOM 10698 N N . ASN D 2 219 ? -61.068 -42.320 -73.845 1.00 76.26 ? 219 ASN D N 1 +ATOM 10699 C CA . ASN D 2 219 ? -61.509 -41.531 -72.705 1.00 65.45 ? 219 ASN D CA 1 +ATOM 10700 C C . ASN D 2 219 ? -62.920 -41.001 -72.949 1.00 66.98 ? 219 ASN D C 1 +ATOM 10701 O O . ASN D 2 219 ? -63.263 -40.648 -74.081 1.00 69.08 ? 219 ASN D O 1 +ATOM 10702 C CB . ASN D 2 219 ? -60.560 -40.364 -72.466 1.00 62.57 ? 219 ASN D CB 1 +ATOM 10703 C CG . ASN D 2 219 ? -60.465 -39.985 -71.008 1.00 62.93 ? 219 ASN D CG 1 +ATOM 10704 O OD1 . ASN D 2 219 ? -61.112 -39.041 -70.554 1.00 62.19 ? 219 ASN D OD1 1 +ATOM 10705 N ND2 . ASN D 2 219 ? -59.659 -40.724 -70.260 1.00 62.45 ? 219 ASN D ND2 1 +ATOM 10706 N N . PRO D 2 220 ? -63.756 -40.922 -71.910 1.00 66.88 ? 220 PRO D N 1 +ATOM 10707 C CA . PRO D 2 220 ? -65.077 -40.305 -72.079 1.00 66.62 ? 220 PRO D CA 1 +ATOM 10708 C C . PRO D 2 220 ? -65.042 -38.795 -71.991 1.00 64.40 ? 220 PRO D C 1 +ATOM 10709 O O . PRO D 2 220 ? -66.020 -38.144 -72.386 1.00 59.68 ? 220 PRO D O 1 +ATOM 10710 C CB . PRO D 2 220 ? -65.889 -40.903 -70.924 1.00 73.34 ? 220 PRO D CB 1 +ATOM 10711 C CG . PRO D 2 220 ? -64.880 -41.171 -69.861 1.00 76.32 ? 220 PRO D CG 1 +ATOM 10712 C CD . PRO D 2 220 ? -63.552 -41.439 -70.546 1.00 73.79 ? 220 PRO D CD 1 +ATOM 10713 N N . VAL D 2 221 ? -63.937 -38.224 -71.521 1.00 64.62 ? 221 VAL D N 1 +ATOM 10714 C CA . VAL D 2 221 ? -63.812 -36.779 -71.389 1.00 63.11 ? 221 VAL D CA 1 +ATOM 10715 C C . VAL D 2 221 ? -63.271 -36.162 -72.668 1.00 61.22 ? 221 VAL D C 1 +ATOM 10716 O O . VAL D 2 221 ? -63.757 -35.120 -73.112 1.00 61.50 ? 221 VAL D O 1 +ATOM 10717 C CB . VAL D 2 221 ? -62.923 -36.436 -70.176 1.00 65.58 ? 221 VAL D CB 1 +ATOM 10718 C CG1 . VAL D 2 221 ? -62.500 -34.974 -70.211 1.00 68.31 ? 221 VAL D CG1 1 +ATOM 10719 C CG2 . VAL D 2 221 ? -63.653 -36.754 -68.878 1.00 71.66 ? 221 VAL D CG2 1 +ATOM 10720 N N . ILE D 2 222 ? -62.268 -36.800 -73.276 1.00 59.40 ? 222 ILE D N 1 +ATOM 10721 C CA . ILE D 2 222 ? -61.742 -36.318 -74.549 1.00 59.22 ? 222 ILE D CA 1 +ATOM 10722 C C . ILE D 2 222 ? -62.853 -36.243 -75.586 1.00 62.32 ? 222 ILE D C 1 +ATOM 10723 O O . ILE D 2 222 ? -62.868 -35.337 -76.429 1.00 63.16 ? 222 ILE D O 1 +ATOM 10724 C CB . ILE D 2 222 ? -60.580 -37.213 -75.021 1.00 57.46 ? 222 ILE D CB 1 +ATOM 10725 C CG1 . ILE D 2 222 ? -59.478 -37.222 -73.968 1.00 62.16 ? 222 ILE D CG1 1 +ATOM 10726 C CG2 . ILE D 2 222 ? -60.013 -36.716 -76.341 1.00 55.14 ? 222 ILE D CG2 1 +ATOM 10727 C CD1 . ILE D 2 222 ? -58.853 -35.866 -73.763 1.00 66.11 ? 222 ILE D CD1 1 +ATOM 10728 N N . ALA D 2 223 ? -63.813 -37.167 -75.527 1.00 59.65 ? 223 ALA D N 1 +ATOM 10729 C CA . ALA D 2 223 ? -64.981 -37.068 -76.394 1.00 59.96 ? 223 ALA D CA 1 +ATOM 10730 C C . ALA D 2 223 ? -65.840 -35.868 -76.020 1.00 61.95 ? 223 ALA D C 1 +ATOM 10731 O O . ALA D 2 223 ? -66.245 -35.087 -76.887 1.00 62.33 ? 223 ALA D O 1 +ATOM 10732 C CB . ALA D 2 223 ? -65.798 -38.358 -76.316 1.00 66.48 ? 223 ALA D CB 1 +ATOM 10733 N N . ALA D 2 224 ? -66.110 -35.693 -74.725 1.00 66.79 ? 224 ALA D N 1 +ATOM 10734 C CA . ALA D 2 224 ? -66.940 -34.581 -74.274 1.00 68.06 ? 224 ALA D CA 1 +ATOM 10735 C C . ALA D 2 224 ? -66.200 -33.247 -74.305 1.00 65.52 ? 224 ALA D C 1 +ATOM 10736 O O . ALA D 2 224 ? -66.837 -32.199 -74.460 1.00 66.21 ? 224 ALA D O 1 +ATOM 10737 C CB . ALA D 2 224 ? -67.468 -34.854 -72.867 1.00 69.97 ? 224 ALA D CB 1 +ATOM 10738 N N . LEU D 2 225 ? -64.872 -33.257 -74.148 1.00 62.67 ? 225 LEU D N 1 +ATOM 10739 C CA . LEU D 2 225 ? -64.116 -32.010 -74.226 1.00 60.94 ? 225 LEU D CA 1 +ATOM 10740 C C . LEU D 2 225 ? -64.274 -31.368 -75.596 1.00 58.08 ? 225 LEU D C 1 +ATOM 10741 O O . LEU D 2 225 ? -64.389 -30.141 -75.704 1.00 54.99 ? 225 LEU D O 1 +ATOM 10742 C CB . LEU D 2 225 ? -62.640 -32.269 -73.902 1.00 60.02 ? 225 LEU D CB 1 +ATOM 10743 C CG . LEU D 2 225 ? -61.685 -31.101 -73.633 1.00 48.28 ? 225 LEU D CG 1 +ATOM 10744 C CD1 . LEU D 2 225 ? -61.065 -30.562 -74.908 1.00 53.91 ? 225 LEU D CD1 1 +ATOM 10745 C CD2 . LEU D 2 225 ? -62.418 -29.994 -72.906 1.00 47.09 ? 225 LEU D CD2 1 +ATOM 10746 N N . LEU D 2 226 ? -64.294 -32.185 -76.655 1.00 59.58 ? 226 LEU D N 1 +ATOM 10747 C CA . LEU D 2 226 ? -64.540 -31.663 -77.995 1.00 59.40 ? 226 LEU D CA 1 +ATOM 10748 C C . LEU D 2 226 ? -65.923 -31.035 -78.093 1.00 59.48 ? 226 LEU D C 1 +ATOM 10749 O O . LEU D 2 226 ? -66.103 -30.013 -78.764 1.00 60.01 ? 226 LEU D O 1 +ATOM 10750 C CB . LEU D 2 226 ? -64.377 -32.776 -79.034 1.00 53.94 ? 226 LEU D CB 1 +ATOM 10751 C CG . LEU D 2 226 ? -62.983 -33.381 -79.238 1.00 56.95 ? 226 LEU D CG 1 +ATOM 10752 C CD1 . LEU D 2 226 ? -63.029 -34.509 -80.265 1.00 59.00 ? 226 LEU D CD1 1 +ATOM 10753 C CD2 . LEU D 2 226 ? -61.969 -32.319 -79.649 1.00 52.85 ? 226 LEU D CD2 1 +ATOM 10754 N N . ARG D 2 227 ? -66.913 -31.631 -77.422 1.00 59.77 ? 227 ARG D N 1 +ATOM 10755 C CA . ARG D 2 227 ? -68.275 -31.108 -77.474 1.00 60.12 ? 227 ARG D CA 1 +ATOM 10756 C C . ARG D 2 227 ? -68.379 -29.747 -76.799 1.00 62.72 ? 227 ARG D C 1 +ATOM 10757 O O . ARG D 2 227 ? -69.163 -28.895 -77.232 1.00 64.54 ? 227 ARG D O 1 +ATOM 10758 C CB . ARG D 2 227 ? -69.241 -32.095 -76.824 1.00 59.85 ? 227 ARG D CB 1 +ATOM 10759 C CG . ARG D 2 227 ? -69.274 -33.456 -77.479 1.00 63.72 ? 227 ARG D CG 1 +ATOM 10760 C CD . ARG D 2 227 ? -69.962 -34.460 -76.579 1.00 76.27 ? 227 ARG D CD 1 +ATOM 10761 N NE . ARG D 2 227 ? -70.029 -35.781 -77.194 1.00 84.13 ? 227 ARG D NE 1 +ATOM 10762 C CZ . ARG D 2 227 ? -70.480 -36.868 -76.577 1.00 85.39 ? 227 ARG D CZ 1 +ATOM 10763 N NH1 . ARG D 2 227 ? -70.509 -38.027 -77.221 1.00 90.18 ? 227 ARG D NH1 1 +ATOM 10764 N NH2 . ARG D 2 227 ? -70.895 -36.796 -75.318 1.00 76.86 ? 227 ARG D NH2 1 +ATOM 10765 N N . ASP D 2 228 ? -67.616 -29.531 -75.726 1.00 63.86 ? 228 ASP D N 1 +ATOM 10766 C CA . ASP D 2 228 ? -67.676 -28.254 -75.021 1.00 66.71 ? 228 ASP D CA 1 +ATOM 10767 C C . ASP D 2 228 ? -67.229 -27.105 -75.919 1.00 66.71 ? 228 ASP D C 1 +ATOM 10768 O O . ASP D 2 228 ? -67.921 -26.089 -76.032 1.00 67.24 ? 228 ASP D O 1 +ATOM 10769 C CB . ASP D 2 228 ? -66.833 -28.317 -73.746 1.00 65.80 ? 228 ASP D CB 1 +ATOM 10770 C CG . ASP D 2 228 ? -67.508 -29.119 -72.645 1.00 69.12 ? 228 ASP D CG 1 +ATOM 10771 O OD1 . ASP D 2 228 ? -68.736 -29.340 -72.741 1.00 66.64 ? 228 ASP D OD1 1 +ATOM 10772 O OD2 . ASP D 2 228 ? -66.815 -29.527 -71.686 1.00 65.75 ? 228 ASP D OD2 1 +ATOM 10773 N N . LEU D 2 229 ? -66.081 -27.258 -76.583 1.00 65.80 ? 229 LEU D N 1 +ATOM 10774 C CA . LEU D 2 229 ? -65.582 -26.195 -77.451 1.00 57.21 ? 229 LEU D CA 1 +ATOM 10775 C C . LEU D 2 229 ? -66.554 -25.889 -78.586 1.00 58.79 ? 229 LEU D C 1 +ATOM 10776 O O . LEU D 2 229 ? -66.622 -24.743 -79.049 1.00 56.15 ? 229 LEU D O 1 +ATOM 10777 C CB . LEU D 2 229 ? -64.208 -26.577 -78.007 1.00 50.29 ? 229 LEU D CB 1 +ATOM 10778 C CG . LEU D 2 229 ? -63.220 -27.086 -76.953 1.00 49.17 ? 229 LEU D CG 1 +ATOM 10779 C CD1 . LEU D 2 229 ? -61.855 -27.420 -77.548 1.00 46.88 ? 229 LEU D CD1 1 +ATOM 10780 C CD2 . LEU D 2 229 ? -63.086 -26.078 -75.831 1.00 53.57 ? 229 LEU D CD2 1 +ATOM 10781 N N . LEU D 2 230 ? -67.328 -26.886 -79.027 1.00 59.61 ? 230 LEU D N 1 +ATOM 10782 C CA . LEU D 2 230 ? -68.262 -26.678 -80.132 1.00 59.12 ? 230 LEU D CA 1 +ATOM 10783 C C . LEU D 2 230 ? -69.361 -25.692 -79.761 1.00 62.39 ? 230 LEU D C 1 +ATOM 10784 O O . LEU D 2 230 ? -69.802 -24.905 -80.607 1.00 65.08 ? 230 LEU D O 1 +ATOM 10785 C CB . LEU D 2 230 ? -68.892 -28.007 -80.557 1.00 57.49 ? 230 LEU D CB 1 +ATOM 10786 C CG . LEU D 2 230 ? -68.000 -29.126 -81.096 1.00 70.71 ? 230 LEU D CG 1 +ATOM 10787 C CD1 . LEU D 2 230 ? -68.798 -30.407 -81.338 1.00 73.60 ? 230 LEU D CD1 1 +ATOM 10788 C CD2 . LEU D 2 230 ? -67.313 -28.688 -82.363 1.00 71.51 ? 230 LEU D CD2 1 +ATOM 10789 N N . SER D 2 231 ? -69.830 -25.735 -78.509 1.00 64.02 ? 231 SER D N 1 +ATOM 10790 C CA . SER D 2 231 ? -71.066 -25.062 -78.126 1.00 65.81 ? 231 SER D CA 1 +ATOM 10791 C C . SER D 2 231 ? -70.993 -24.245 -76.840 1.00 60.35 ? 231 SER D C 1 +ATOM 10792 O O . SER D 2 231 ? -71.968 -23.551 -76.530 1.00 59.90 ? 231 SER D O 1 +ATOM 10793 C CB . SER D 2 231 ? -72.214 -26.079 -78.004 1.00 65.74 ? 231 SER D CB 1 +ATOM 10794 O OG . SER D 2 231 ? -71.868 -27.145 -77.143 1.00 72.22 ? 231 SER D OG 1 +ATOM 10795 N N . GLN D 2 232 ? -69.918 -24.337 -76.060 1.00 57.72 ? 232 GLN D N 1 +ATOM 10796 C CA . GLN D 2 232 ? -69.837 -23.563 -74.828 1.00 54.20 ? 232 GLN D CA 1 +ATOM 10797 C C . GLN D 2 232 ? -69.798 -22.071 -75.146 1.00 55.97 ? 232 GLN D C 1 +ATOM 10798 O O . GLN D 2 232 ? -69.342 -21.656 -76.215 1.00 57.38 ? 232 GLN D O 1 +ATOM 10799 C CB . GLN D 2 232 ? -68.595 -23.956 -74.032 1.00 57.81 ? 232 GLN D CB 1 +ATOM 10800 C CG . GLN D 2 232 ? -68.648 -23.598 -72.565 1.00 62.30 ? 232 GLN D CG 1 +ATOM 10801 C CD . GLN D 2 232 ? -69.456 -24.594 -71.758 1.00 63.83 ? 232 GLN D CD 1 +ATOM 10802 O OE1 . GLN D 2 232 ? -70.620 -24.860 -72.058 1.00 77.85 ? 232 GLN D OE1 1 +ATOM 10803 N NE2 . GLN D 2 232 ? -68.837 -25.157 -70.729 1.00 55.86 ? 232 GLN D NE2 1 +ATOM 10804 N N . LYS D 2 233 ? -70.271 -21.260 -74.202 1.00 61.32 ? 233 LYS D N 1 +ATOM 10805 C CA . LYS D 2 233 ? -70.384 -19.823 -74.428 1.00 64.44 ? 233 LYS D CA 1 +ATOM 10806 C C . LYS D 2 233 ? -69.027 -19.147 -74.305 1.00 57.23 ? 233 LYS D C 1 +ATOM 10807 O O . LYS D 2 233 ? -68.227 -19.480 -73.424 1.00 53.28 ? 233 LYS D O 1 +ATOM 10808 C CB . LYS D 2 233 ? -71.366 -19.187 -73.438 1.00 71.57 ? 233 LYS D CB 1 +ATOM 10809 C CG . LYS D 2 233 ? -71.643 -17.696 -73.696 1.00 67.49 ? 233 LYS D CG 1 +ATOM 10810 C CD . LYS D 2 233 ? -72.754 -17.147 -72.789 1.00 69.38 ? 233 LYS D CD 1 +ATOM 10811 C CE . LYS D 2 233 ? -73.104 -15.694 -73.125 1.00 53.63 ? 233 LYS D CE 1 +ATOM 10812 N NZ . LYS D 2 233 ? -74.258 -15.175 -72.328 1.00 38.00 ? 233 LYS D NZ 1 +ATOM 10813 N N . ILE D 2 234 ? -68.769 -18.202 -75.202 1.00 55.92 ? 234 ILE D N 1 +ATOM 10814 C CA . ILE D 2 234 ? -67.511 -17.464 -75.197 1.00 57.92 ? 234 ILE D CA 1 +ATOM 10815 C C . ILE D 2 234 ? -67.599 -16.367 -74.145 1.00 55.76 ? 234 ILE D C 1 +ATOM 10816 O O . ILE D 2 234 ? -68.533 -15.558 -74.159 1.00 53.52 ? 234 ILE D O 1 +ATOM 10817 C CB . ILE D 2 234 ? -67.205 -16.868 -76.576 1.00 61.32 ? 234 ILE D CB 1 +ATOM 10818 C CG1 . ILE D 2 234 ? -67.095 -17.957 -77.643 1.00 57.41 ? 234 ILE D CG1 1 +ATOM 10819 C CG2 . ILE D 2 234 ? -65.896 -16.105 -76.517 1.00 59.29 ? 234 ILE D CG2 1 +ATOM 10820 C CD1 . ILE D 2 234 ? -65.984 -18.943 -77.399 1.00 59.94 ? 234 ILE D CD1 1 +ATOM 10821 N N . SER D 2 235 ? -66.647 -16.360 -73.211 1.00 58.84 ? 235 SER D N 1 +ATOM 10822 C CA . SER D 2 235 ? -66.572 -15.345 -72.164 1.00 56.17 ? 235 SER D CA 1 +ATOM 10823 C C . SER D 2 235 ? -65.594 -14.229 -72.508 1.00 53.61 ? 235 SER D C 1 +ATOM 10824 O O . SER D 2 235 ? -65.944 -13.050 -72.408 1.00 54.44 ? 235 SER D O 1 +ATOM 10825 C CB . SER D 2 235 ? -66.190 -15.976 -70.822 1.00 56.62 ? 235 SER D CB 1 +ATOM 10826 O OG . SER D 2 235 ? -64.837 -16.378 -70.824 1.00 64.01 ? 235 SER D OG 1 +ATOM 10827 N N . SER D 2 236 ? -64.361 -14.572 -72.885 1.00 56.75 ? 236 SER D N 1 +ATOM 10828 C CA . SER D 2 236 ? -63.367 -13.567 -73.234 1.00 60.26 ? 236 SER D CA 1 +ATOM 10829 C C . SER D 2 236 ? -62.508 -14.030 -74.401 1.00 62.45 ? 236 SER D C 1 +ATOM 10830 O O . SER D 2 236 ? -62.188 -15.215 -74.532 1.00 61.67 ? 236 SER D O 1 +ATOM 10831 C CB . SER D 2 236 ? -62.452 -13.229 -72.058 1.00 56.83 ? 236 SER D CB 1 +ATOM 10832 O OG . SER D 2 236 ? -61.492 -12.267 -72.459 1.00 60.59 ? 236 SER D OG 1 +ATOM 10833 N N . VAL D 2 237 ? -62.120 -13.064 -75.235 1.00 60.79 ? 237 VAL D N 1 +ATOM 10834 C CA . VAL D 2 237 ? -61.300 -13.295 -76.419 1.00 49.52 ? 237 VAL D CA 1 +ATOM 10835 C C . VAL D 2 237 ? -60.107 -12.354 -76.373 1.00 46.21 ? 237 VAL D C 1 +ATOM 10836 O O . VAL D 2 237 ? -60.273 -11.142 -76.204 1.00 52.36 ? 237 VAL D O 1 +ATOM 10837 C CB . VAL D 2 237 ? -62.098 -13.068 -77.714 1.00 47.84 ? 237 VAL D CB 1 +ATOM 10838 C CG1 . VAL D 2 237 ? -61.215 -13.305 -78.919 1.00 54.08 ? 237 VAL D CG1 1 +ATOM 10839 C CG2 . VAL D 2 237 ? -63.314 -13.960 -77.746 1.00 53.59 ? 237 VAL D CG2 1 +ATOM 10840 N N . GLY D 2 238 ? -58.919 -12.899 -76.571 1.00 41.78 ? 238 GLY D N 1 +ATOM 10841 C CA . GLY D 2 238 ? -57.709 -12.101 -76.544 1.00 40.18 ? 238 GLY D CA 1 +ATOM 10842 C C . GLY D 2 238 ? -56.741 -12.557 -77.610 1.00 43.84 ? 238 GLY D C 1 +ATOM 10843 O O . GLY D 2 238 ? -56.687 -13.734 -77.970 1.00 48.22 ? 238 GLY D O 1 +ATOM 10844 N N . MET D 2 239 ? -55.974 -11.605 -78.117 1.00 48.35 ? 239 MET D N 1 +ATOM 10845 C CA . MET D 2 239 ? -54.994 -11.888 -79.150 1.00 60.44 ? 239 MET D CA 1 +ATOM 10846 C C . MET D 2 239 ? -53.673 -12.313 -78.514 1.00 69.39 ? 239 MET D C 1 +ATOM 10847 O O . MET D 2 239 ? -53.231 -11.721 -77.524 1.00 68.34 ? 239 MET D O 1 +ATOM 10848 C CB . MET D 2 239 ? -54.801 -10.652 -80.032 1.00 63.40 ? 239 MET D CB 1 +ATOM 10849 C CG . MET D 2 239 ? -53.898 -10.856 -81.230 1.00 73.06 ? 239 MET D CG 1 +ATOM 10850 S SD . MET D 2 239 ? -53.457 -9.302 -82.039 1.00 68.07 ? 239 MET D SD 1 +ATOM 10851 C CE . MET D 2 239 ? -55.048 -8.700 -82.541 1.00 46.99 ? 239 MET D CE 1 +ATOM 10852 N N . LYS D 2 240 ? -53.062 -13.363 -79.067 1.00 67.53 ? 240 LYS D N 1 +ATOM 10853 C CA . LYS D 2 240 ? -51.732 -13.772 -78.634 1.00 69.60 ? 240 LYS D CA 1 +ATOM 10854 C C . LYS D 2 240 ? -50.673 -12.943 -79.349 1.00 87.22 ? 240 LYS D C 1 +ATOM 10855 O O . LYS D 2 240 ? -50.867 -12.493 -80.482 1.00 87.46 ? 240 LYS D O 1 +ATOM 10856 C CB . LYS D 2 240 ? -51.480 -15.256 -78.918 1.00 58.08 ? 240 LYS D CB 1 +ATOM 10857 C CG . LYS D 2 240 ? -50.167 -15.781 -78.339 1.00 67.64 ? 240 LYS D CG 1 +ATOM 10858 C CD . LYS D 2 240 ? -49.878 -17.203 -78.774 1.00 76.30 ? 240 LYS D CD 1 +ATOM 10859 C CE . LYS D 2 240 ? -50.510 -18.217 -77.817 1.00 69.52 ? 240 LYS D CE 1 +ATOM 10860 N NZ . LYS D 2 240 ? -49.844 -18.316 -76.481 1.00 38.00 ? 240 LYS D NZ 1 +ATOM 10861 N N . SER D 2 241 ? -49.541 -12.753 -78.683 1.00 82.41 ? 241 SER D N 1 +ATOM 10862 C CA . SER D 2 241 ? -48.427 -12.020 -79.259 1.00 89.53 ? 241 SER D CA 1 +ATOM 10863 C C . SER D 2 241 ? -47.243 -12.957 -79.481 1.00 92.00 ? 241 SER D C 1 +ATOM 10864 O O . SER D 2 241 ? -47.188 -14.068 -78.943 1.00 72.38 ? 241 SER D O 1 +ATOM 10865 C CB . SER D 2 241 ? -48.027 -10.842 -78.362 1.00 84.86 ? 241 SER D CB 1 +ATOM 10866 O OG . SER D 2 241 ? -47.123 -9.978 -79.029 1.00 95.91 ? 241 SER D OG 1 +ATOM 10867 N N . GLY D 2 242 ? -46.314 -12.506 -80.330 1.00 100.88 ? 242 GLY D N 1 +ATOM 10868 C CA . GLY D 2 242 ? -45.044 -13.173 -80.547 1.00 102.43 ? 242 GLY D CA 1 +ATOM 10869 C C . GLY D 2 242 ? -45.057 -14.349 -81.502 1.00 106.42 ? 242 GLY D C 1 +ATOM 10870 O O . GLY D 2 242 ? -43.984 -14.888 -81.806 1.00 107.48 ? 242 GLY D O 1 +ATOM 10871 N N . GLY D 2 243 ? -46.224 -14.768 -81.991 1.00 106.60 ? 243 GLY D N 1 +ATOM 10872 C CA . GLY D 2 243 ? -46.314 -15.905 -82.879 1.00 90.30 ? 243 GLY D CA 1 +ATOM 10873 C C . GLY D 2 243 ? -46.087 -15.533 -84.332 1.00 84.72 ? 243 GLY D C 1 +ATOM 10874 O O . GLY D 2 243 ? -45.828 -14.384 -84.687 1.00 74.37 ? 243 GLY D O 1 +ATOM 10875 N N . THR D 2 244 ? -46.173 -16.554 -85.184 1.00 92.69 ? 244 THR D N 1 +ATOM 10876 C CA . THR D 2 244 ? -46.025 -16.342 -86.620 1.00 75.52 ? 244 THR D CA 1 +ATOM 10877 C C . THR D 2 244 ? -47.248 -15.639 -87.201 1.00 63.88 ? 244 THR D C 1 +ATOM 10878 O O . THR D 2 244 ? -47.147 -14.535 -87.746 1.00 56.45 ? 244 THR D O 1 +ATOM 10879 C CB . THR D 2 244 ? -45.786 -17.680 -87.322 1.00 74.70 ? 244 THR D CB 1 +ATOM 10880 O OG1 . THR D 2 244 ? -45.767 -18.740 -86.352 1.00 75.26 ? 244 THR D OG1 1 +ATOM 10881 C CG2 . THR D 2 244 ? -44.461 -17.655 -88.068 1.00 70.67 ? 244 THR D CG2 1 +ATOM 10882 N N . GLN D 2 245 ? -48.414 -16.260 -87.083 1.00 63.74 ? 245 GLN D N 1 +ATOM 10883 C CA . GLN D 2 245 ? -49.657 -15.742 -87.635 1.00 52.65 ? 245 GLN D CA 1 +ATOM 10884 C C . GLN D 2 245 ? -50.650 -15.486 -86.503 1.00 66.48 ? 245 GLN D C 1 +ATOM 10885 O O . GLN D 2 245 ? -50.332 -15.656 -85.322 1.00 72.73 ? 245 GLN D O 1 +ATOM 10886 C CB . GLN D 2 245 ? -50.210 -16.719 -88.669 1.00 57.67 ? 245 GLN D CB 1 +ATOM 10887 C CG . GLN D 2 245 ? -49.649 -16.482 -90.059 1.00 59.34 ? 245 GLN D CG 1 +ATOM 10888 C CD . GLN D 2 245 ? -49.797 -17.690 -90.957 1.00 57.74 ? 245 GLN D CD 1 +ATOM 10889 O OE1 . GLN D 2 245 ? -50.874 -18.284 -91.047 1.00 62.63 ? 245 GLN D OE1 1 +ATOM 10890 N NE2 . GLN D 2 245 ? -48.712 -18.065 -91.628 1.00 49.56 ? 245 GLN D NE2 1 +ATOM 10891 N N . LEU D 2 246 ? -51.873 -15.096 -86.870 1.00 63.41 ? 246 LEU D N 1 +ATOM 10892 C CA . LEU D 2 246 ? -52.883 -14.701 -85.889 1.00 60.93 ? 246 LEU D CA 1 +ATOM 10893 C C . LEU D 2 246 ? -53.460 -15.916 -85.171 1.00 54.94 ? 246 LEU D C 1 +ATOM 10894 O O . LEU D 2 246 ? -54.018 -16.814 -85.809 1.00 54.22 ? 246 LEU D O 1 +ATOM 10895 C CB . LEU D 2 246 ? -54.014 -13.922 -86.555 1.00 48.31 ? 246 LEU D CB 1 +ATOM 10896 C CG . LEU D 2 246 ? -55.061 -13.452 -85.544 1.00 38.16 ? 246 LEU D CG 1 +ATOM 10897 C CD1 . LEU D 2 246 ? -54.541 -12.225 -84.823 1.00 48.16 ? 246 LEU D CD1 1 +ATOM 10898 C CD2 . LEU D 2 246 ? -56.403 -13.170 -86.195 1.00 38.00 ? 246 LEU D CD2 1 +ATOM 10899 N N . LYS D 2 247 ? -53.358 -15.922 -83.844 1.00 52.18 ? 247 LYS D N 1 +ATOM 10900 C CA . LYS D 2 247 ? -53.968 -16.955 -83.016 1.00 54.17 ? 247 LYS D CA 1 +ATOM 10901 C C . LYS D 2 247 ? -54.565 -16.284 -81.786 1.00 59.05 ? 247 LYS D C 1 +ATOM 10902 O O . LYS D 2 247 ? -53.882 -15.516 -81.101 1.00 63.61 ? 247 LYS D O 1 +ATOM 10903 C CB . LYS D 2 247 ? -52.953 -18.046 -82.629 1.00 53.38 ? 247 LYS D CB 1 +ATOM 10904 C CG . LYS D 2 247 ? -51.514 -17.561 -82.480 1.00 67.62 ? 247 LYS D CG 1 +ATOM 10905 C CD . LYS D 2 247 ? -50.501 -18.706 -82.565 1.00 73.16 ? 247 LYS D CD 1 +ATOM 10906 C CE . LYS D 2 247 ? -49.081 -18.173 -82.786 1.00 84.16 ? 247 LYS D CE 1 +ATOM 10907 N NZ . LYS D 2 247 ? -48.020 -19.229 -82.819 1.00 95.17 ? 247 LYS D NZ 1 +ATOM 10908 N N . LEU D 2 248 ? -55.849 -16.541 -81.540 1.00 54.24 ? 248 LEU D N 1 +ATOM 10909 C CA . LEU D 2 248 ? -56.609 -15.900 -80.476 1.00 46.95 ? 248 LEU D CA 1 +ATOM 10910 C C . LEU D 2 248 ? -56.826 -16.843 -79.297 1.00 46.78 ? 248 LEU D C 1 +ATOM 10911 O O . LEU D 2 248 ? -56.978 -18.056 -79.466 1.00 46.31 ? 248 LEU D O 1 +ATOM 10912 C CB . LEU D 2 248 ? -57.964 -15.428 -81.005 1.00 38.00 ? 248 LEU D CB 1 +ATOM 10913 C CG . LEU D 2 248 ? -58.054 -13.970 -81.435 1.00 38.00 ? 248 LEU D CG 1 +ATOM 10914 C CD1 . LEU D 2 248 ? -56.844 -13.573 -82.245 1.00 42.03 ? 248 LEU D CD1 1 +ATOM 10915 C CD2 . LEU D 2 248 ? -59.328 -13.759 -82.235 1.00 38.00 ? 248 LEU D CD2 1 +ATOM 10916 N N . ILE D 2 249 ? -56.880 -16.267 -78.100 1.00 43.37 ? 249 ILE D N 1 +ATOM 10917 C CA . ILE D 2 249 ? -57.116 -17.025 -76.878 1.00 40.22 ? 249 ILE D CA 1 +ATOM 10918 C C . ILE D 2 249 ? -58.570 -16.851 -76.476 1.00 43.61 ? 249 ILE D C 1 +ATOM 10919 O O . ILE D 2 249 ? -59.032 -15.728 -76.243 1.00 45.38 ? 249 ILE D O 1 +ATOM 10920 C CB . ILE D 2 249 ? -56.186 -16.580 -75.745 1.00 38.00 ? 249 ILE D CB 1 +ATOM 10921 C CG1 . ILE D 2 249 ? -54.781 -17.111 -75.997 1.00 46.91 ? 249 ILE D CG1 1 +ATOM 10922 C CG2 . ILE D 2 249 ? -56.722 -17.075 -74.413 1.00 38.00 ? 249 ILE D CG2 1 +ATOM 10923 C CD1 . ILE D 2 249 ? -53.957 -16.215 -76.867 1.00 41.75 ? 249 ILE D CD1 1 +ATOM 10924 N N . MET D 2 250 ? -59.270 -17.966 -76.342 1.00 49.61 ? 250 MET D N 1 +ATOM 10925 C CA . MET D 2 250 ? -60.668 -17.977 -75.957 1.00 50.32 ? 250 MET D CA 1 +ATOM 10926 C C . MET D 2 250 ? -60.786 -18.394 -74.503 1.00 60.67 ? 250 MET D C 1 +ATOM 10927 O O . MET D 2 250 ? -60.028 -19.243 -74.031 1.00 58.96 ? 250 MET D O 1 +ATOM 10928 C CB . MET D 2 250 ? -61.459 -18.942 -76.837 1.00 49.85 ? 250 MET D CB 1 +ATOM 10929 C CG . MET D 2 250 ? -61.291 -18.671 -78.303 1.00 45.42 ? 250 MET D CG 1 +ATOM 10930 S SD . MET D 2 250 ? -62.572 -17.547 -78.838 1.00 45.25 ? 250 MET D SD 1 +ATOM 10931 C CE . MET D 2 250 ? -61.925 -17.044 -80.421 1.00 52.33 ? 250 MET D CE 1 +ATOM 10932 N N . SER D 2 251 ? -61.726 -17.780 -73.793 1.00 67.99 ? 251 SER D N 1 +ATOM 10933 C CA . SER D 2 251 ? -62.088 -18.187 -72.444 1.00 63.60 ? 251 SER D CA 1 +ATOM 10934 C C . SER D 2 251 ? -63.575 -18.502 -72.419 1.00 64.39 ? 251 SER D C 1 +ATOM 10935 O O . SER D 2 251 ? -64.373 -17.827 -73.079 1.00 61.74 ? 251 SER D O 1 +ATOM 10936 C CB . SER D 2 251 ? -61.746 -17.105 -71.419 1.00 55.37 ? 251 SER D CB 1 +ATOM 10937 O OG . SER D 2 251 ? -60.343 -16.936 -71.315 1.00 52.06 ? 251 SER D OG 1 +ATOM 10938 N N . PHE D 2 252 ? -63.941 -19.535 -71.668 1.00 64.22 ? 252 PHE D N 1 +ATOM 10939 C CA . PHE D 2 252 ? -65.291 -20.074 -71.691 1.00 61.01 ? 252 PHE D CA 1 +ATOM 10940 C C . PHE D 2 252 ? -65.986 -19.889 -70.351 1.00 60.14 ? 252 PHE D C 1 +ATOM 10941 O O . PHE D 2 252 ? -65.404 -19.422 -69.368 1.00 58.56 ? 252 PHE D O 1 +ATOM 10942 C CB . PHE D 2 252 ? -65.272 -21.551 -72.081 1.00 61.49 ? 252 PHE D CB 1 +ATOM 10943 C CG . PHE D 2 252 ? -64.731 -21.795 -73.453 1.00 59.74 ? 252 PHE D CG 1 +ATOM 10944 C CD1 . PHE D 2 252 ? -65.551 -21.684 -74.562 1.00 56.47 ? 252 PHE D CD1 1 +ATOM 10945 C CD2 . PHE D 2 252 ? -63.400 -22.117 -73.636 1.00 59.36 ? 252 PHE D CD2 1 +ATOM 10946 C CE1 . PHE D 2 252 ? -65.057 -21.907 -75.825 1.00 55.89 ? 252 PHE D CE1 1 +ATOM 10947 C CE2 . PHE D 2 252 ? -62.897 -22.336 -74.900 1.00 63.81 ? 252 PHE D CE2 1 +ATOM 10948 C CZ . PHE D 2 252 ? -63.729 -22.231 -75.997 1.00 62.91 ? 252 PHE D CZ 1 +ATOM 10949 N N . GLN D 2 253 ? -67.266 -20.266 -70.342 1.00 59.10 ? 253 GLN D N 1 +ATOM 10950 C CA . GLN D 2 253 ? -68.099 -20.135 -69.155 1.00 65.34 ? 253 GLN D CA 1 +ATOM 10951 C C . GLN D 2 253 ? -67.619 -21.031 -68.015 1.00 67.97 ? 253 GLN D C 1 +ATOM 10952 O O . GLN D 2 253 ? -67.904 -20.739 -66.848 1.00 70.74 ? 253 GLN D O 1 +ATOM 10953 C CB . GLN D 2 253 ? -69.549 -20.453 -69.527 1.00 65.73 ? 253 GLN D CB 1 +ATOM 10954 C CG . GLN D 2 253 ? -70.590 -20.004 -68.522 1.00 76.80 ? 253 GLN D CG 1 +ATOM 10955 C CD . GLN D 2 253 ? -72.004 -20.300 -68.991 1.00 85.51 ? 253 GLN D CD 1 +ATOM 10956 O OE1 . GLN D 2 253 ? -72.785 -19.387 -69.274 1.00 85.44 ? 253 GLN D OE1 1 +ATOM 10957 N NE2 . GLN D 2 253 ? -72.336 -21.582 -69.090 1.00 80.81 ? 253 GLN D NE2 1 +ATOM 10958 N N . ASN D 2 254 ? -66.886 -22.101 -68.324 1.00 65.66 ? 254 ASN D N 1 +ATOM 10959 C CA . ASN D 2 254 ? -66.356 -23.020 -67.326 1.00 60.87 ? 254 ASN D CA 1 +ATOM 10960 C C . ASN D 2 254 ? -64.878 -22.774 -67.049 1.00 56.82 ? 254 ASN D C 1 +ATOM 10961 O O . ASN D 2 254 ? -64.137 -23.720 -66.764 1.00 52.47 ? 254 ASN D O 1 +ATOM 10962 C CB . ASN D 2 254 ? -66.570 -24.460 -67.777 1.00 62.35 ? 254 ASN D CB 1 +ATOM 10963 C CG . ASN D 2 254 ? -66.076 -24.694 -69.179 1.00 65.22 ? 254 ASN D CG 1 +ATOM 10964 O OD1 . ASN D 2 254 ? -66.717 -24.288 -70.147 1.00 67.26 ? 254 ASN D OD1 1 +ATOM 10965 N ND2 . ASN D 2 254 ? -64.929 -25.342 -69.303 1.00 62.27 ? 254 ASN D ND2 1 +ATOM 10966 N N . TYR D 2 255 ? -64.432 -21.527 -67.191 1.00 62.22 ? 255 TYR D N 1 +ATOM 10967 C CA . TYR D 2 255 ? -63.083 -21.117 -66.814 1.00 67.44 ? 255 TYR D CA 1 +ATOM 10968 C C . TYR D 2 255 ? -62.001 -21.784 -67.662 1.00 66.05 ? 255 TYR D C 1 +ATOM 10969 O O . TYR D 2 255 ? -60.809 -21.517 -67.482 1.00 60.93 ? 255 TYR D O 1 +ATOM 10970 C CB . TYR D 2 255 ? -62.829 -21.403 -65.335 1.00 63.75 ? 255 TYR D CB 1 +ATOM 10971 C CG . TYR D 2 255 ? -63.749 -20.647 -64.412 1.00 72.32 ? 255 TYR D CG 1 +ATOM 10972 C CD1 . TYR D 2 255 ? -65.001 -21.149 -64.068 1.00 84.86 ? 255 TYR D CD1 1 +ATOM 10973 C CD2 . TYR D 2 255 ? -63.362 -19.426 -63.883 1.00 68.23 ? 255 TYR D CD2 1 +ATOM 10974 C CE1 . TYR D 2 255 ? -65.842 -20.452 -63.212 1.00 92.76 ? 255 TYR D CE1 1 +ATOM 10975 C CE2 . TYR D 2 255 ? -64.192 -18.723 -63.034 1.00 81.93 ? 255 TYR D CE2 1 +ATOM 10976 C CZ . TYR D 2 255 ? -65.431 -19.239 -62.700 1.00 98.36 ? 255 TYR D CZ 1 +ATOM 10977 O OH . TYR D 2 255 ? -66.256 -18.535 -61.850 1.00 103.78 ? 255 TYR D OH 1 +ATOM 10978 N N . GLY D 2 256 ? -62.409 -22.681 -68.555 1.00 64.51 ? 256 GLY D N 1 +ATOM 10979 C CA . GLY D 2 256 ? -61.478 -23.243 -69.502 1.00 63.37 ? 256 GLY D CA 1 +ATOM 10980 C C . GLY D 2 256 ? -61.113 -22.259 -70.596 1.00 58.63 ? 256 GLY D C 1 +ATOM 10981 O O . GLY D 2 256 ? -61.834 -21.303 -70.887 1.00 57.84 ? 256 GLY D O 1 +ATOM 10982 N N . GLN D 2 257 ? -59.961 -22.507 -71.213 1.00 56.55 ? 257 GLN D N 1 +ATOM 10983 C CA . GLN D 2 257 ? -59.477 -21.674 -72.300 1.00 52.09 ? 257 GLN D CA 1 +ATOM 10984 C C . GLN D 2 257 ? -58.941 -22.561 -73.419 1.00 53.21 ? 257 GLN D C 1 +ATOM 10985 O O . GLN D 2 257 ? -58.725 -23.765 -73.246 1.00 53.44 ? 257 GLN D O 1 +ATOM 10986 C CB . GLN D 2 257 ? -58.411 -20.686 -71.815 1.00 49.43 ? 257 GLN D CB 1 +ATOM 10987 C CG . GLN D 2 257 ? -57.652 -21.121 -70.578 1.00 48.81 ? 257 GLN D CG 1 +ATOM 10988 C CD . GLN D 2 257 ? -56.783 -20.002 -70.037 1.00 51.10 ? 257 GLN D CD 1 +ATOM 10989 O OE1 . GLN D 2 257 ? -57.191 -18.834 -69.999 1.00 39.63 ? 257 GLN D OE1 1 +ATOM 10990 N NE2 . GLN D 2 257 ? -55.563 -20.347 -69.648 1.00 54.43 ? 257 GLN D NE2 1 +ATOM 10991 N N . ALA D 2 258 ? -58.724 -21.942 -74.578 1.00 52.11 ? 258 ALA D N 1 +ATOM 10992 C CA . ALA D 2 258 ? -58.308 -22.660 -75.776 1.00 49.17 ? 258 ALA D CA 1 +ATOM 10993 C C . ALA D 2 258 ? -57.662 -21.688 -76.752 1.00 47.96 ? 258 ALA D C 1 +ATOM 10994 O O . ALA D 2 258 ? -57.891 -20.478 -76.689 1.00 54.32 ? 258 ALA D O 1 +ATOM 10995 C CB . ALA D 2 258 ? -59.496 -23.365 -76.435 1.00 46.19 ? 258 ALA D CB 1 +ATOM 10996 N N . LEU D 2 259 ? -56.833 -22.232 -77.643 1.00 47.35 ? 259 LEU D N 1 +ATOM 10997 C CA . LEU D 2 259 ? -56.281 -21.466 -78.752 1.00 43.02 ? 259 LEU D CA 1 +ATOM 10998 C C . LEU D 2 259 ? -57.245 -21.500 -79.929 1.00 46.57 ? 259 LEU D C 1 +ATOM 10999 O O . LEU D 2 259 ? -57.971 -22.475 -80.131 1.00 51.52 ? 259 LEU D O 1 +ATOM 11000 C CB . LEU D 2 259 ? -54.927 -22.021 -79.195 1.00 38.96 ? 259 LEU D CB 1 +ATOM 11001 C CG . LEU D 2 259 ? -53.868 -20.955 -79.457 1.00 40.01 ? 259 LEU D CG 1 +ATOM 11002 C CD1 . LEU D 2 259 ? -53.528 -20.299 -78.133 1.00 54.22 ? 259 LEU D CD1 1 +ATOM 11003 C CD2 . LEU D 2 259 ? -52.623 -21.534 -80.113 1.00 38.00 ? 259 LEU D CD2 1 +ATOM 11004 N N . PHE D 2 260 ? -57.222 -20.441 -80.732 1.00 44.58 ? 260 PHE D N 1 +ATOM 11005 C CA . PHE D 2 260 ? -58.178 -20.303 -81.822 1.00 40.31 ? 260 PHE D CA 1 +ATOM 11006 C C . PHE D 2 260 ? -57.466 -19.795 -83.064 1.00 41.46 ? 260 PHE D C 1 +ATOM 11007 O O . PHE D 2 260 ? -56.935 -18.681 -83.062 1.00 41.05 ? 260 PHE D O 1 +ATOM 11008 C CB . PHE D 2 260 ? -59.311 -19.350 -81.438 1.00 38.00 ? 260 PHE D CB 1 +ATOM 11009 C CG . PHE D 2 260 ? -60.275 -19.098 -82.549 1.00 41.12 ? 260 PHE D CG 1 +ATOM 11010 C CD1 . PHE D 2 260 ? -61.346 -19.946 -82.755 1.00 43.02 ? 260 PHE D CD1 1 +ATOM 11011 C CD2 . PHE D 2 260 ? -60.101 -18.024 -83.406 1.00 44.58 ? 260 PHE D CD2 1 +ATOM 11012 C CE1 . PHE D 2 260 ? -62.242 -19.717 -83.781 1.00 44.26 ? 260 PHE D CE1 1 +ATOM 11013 C CE2 . PHE D 2 260 ? -60.988 -17.796 -84.440 1.00 45.00 ? 260 PHE D CE2 1 +ATOM 11014 C CZ . PHE D 2 260 ? -62.059 -18.643 -84.627 1.00 44.66 ? 260 PHE D CZ 1 +ATOM 11015 N N . LYS D 2 261 ? -57.491 -20.591 -84.128 1.00 42.90 ? 261 LYS D N 1 +ATOM 11016 C CA . LYS D 2 261 ? -56.980 -20.187 -85.422 1.00 41.99 ? 261 LYS D CA 1 +ATOM 11017 C C . LYS D 2 261 ? -58.136 -20.114 -86.414 1.00 44.73 ? 261 LYS D C 1 +ATOM 11018 O O . LYS D 2 261 ? -58.902 -21.077 -86.542 1.00 47.68 ? 261 LYS D O 1 +ATOM 11019 C CB . LYS D 2 261 ? -55.890 -21.171 -85.925 1.00 39.22 ? 261 LYS D CB 1 +ATOM 11020 C CG . LYS D 2 261 ? -54.641 -21.179 -85.040 1.00 46.40 ? 261 LYS D CG 1 +ATOM 11021 C CD . LYS D 2 261 ? -53.469 -21.979 -85.610 1.00 52.53 ? 261 LYS D CD 1 +ATOM 11022 C CE . LYS D 2 261 ? -52.228 -21.832 -84.716 1.00 56.65 ? 261 LYS D CE 1 +ATOM 11023 N NZ . LYS D 2 261 ? -51.061 -22.645 -85.163 1.00 56.87 ? 261 LYS D NZ 1 +ATOM 11024 N N . PRO D 2 262 ? -58.323 -18.987 -87.094 1.00 42.98 ? 262 PRO D N 1 +ATOM 11025 C CA . PRO D 2 262 ? -59.495 -18.831 -87.965 1.00 47.18 ? 262 PRO D CA 1 +ATOM 11026 C C . PRO D 2 262 ? -59.364 -19.590 -89.277 1.00 55.63 ? 262 PRO D C 1 +ATOM 11027 O O . PRO D 2 262 ? -58.408 -20.344 -89.484 1.00 57.26 ? 262 PRO D O 1 +ATOM 11028 C CB . PRO D 2 262 ? -59.552 -17.317 -88.217 1.00 44.88 ? 262 PRO D CB 1 +ATOM 11029 C CG . PRO D 2 262 ? -58.523 -16.706 -87.302 1.00 42.99 ? 262 PRO D CG 1 +ATOM 11030 C CD . PRO D 2 262 ? -57.511 -17.767 -87.046 1.00 39.28 ? 262 PRO D CD 1 +ATOM 11031 N N . MET D 2 263 ? -60.332 -19.378 -90.173 1.00 55.38 ? 263 MET D N 1 +ATOM 11032 C CA . MET D 2 263 ? -60.367 -20.096 -91.443 1.00 50.98 ? 263 MET D CA 1 +ATOM 11033 C C . MET D 2 263 ? -59.155 -19.769 -92.305 1.00 56.61 ? 263 MET D C 1 +ATOM 11034 O O . MET D 2 263 ? -58.409 -20.667 -92.710 1.00 62.43 ? 263 MET D O 1 +ATOM 11035 C CB . MET D 2 263 ? -61.654 -19.770 -92.191 1.00 53.17 ? 263 MET D CB 1 +ATOM 11036 C CG . MET D 2 263 ? -61.745 -20.436 -93.540 1.00 57.46 ? 263 MET D CG 1 +ATOM 11037 S SD . MET D 2 263 ? -63.422 -20.967 -93.912 1.00 59.99 ? 263 MET D SD 1 +ATOM 11038 C CE . MET D 2 263 ? -63.100 -22.269 -95.104 1.00 56.55 ? 263 MET D CE 1 +ATOM 11039 N N . LYS D 2 264 ? -58.995 -18.491 -92.661 1.00 54.52 ? 264 LYS D N 1 +ATOM 11040 C CA . LYS D 2 264 ? -57.859 -17.978 -93.427 1.00 59.39 ? 264 LYS D CA 1 +ATOM 11041 C C . LYS D 2 264 ? -57.884 -18.396 -94.897 1.00 62.21 ? 264 LYS D C 1 +ATOM 11042 O O . LYS D 2 264 ? -57.582 -17.580 -95.773 1.00 60.05 ? 264 LYS D O 1 +ATOM 11043 C CB . LYS D 2 264 ? -56.531 -18.396 -92.774 1.00 56.80 ? 264 LYS D CB 1 +ATOM 11044 C CG . LYS D 2 264 ? -55.353 -17.514 -93.170 1.00 61.32 ? 264 LYS D CG 1 +ATOM 11045 C CD . LYS D 2 264 ? -55.498 -16.096 -92.626 1.00 78.10 ? 264 LYS D CD 1 +ATOM 11046 C CE . LYS D 2 264 ? -54.944 -15.025 -93.591 1.00 77.98 ? 264 LYS D CE 1 +ATOM 11047 N NZ . LYS D 2 264 ? -55.685 -14.887 -94.899 1.00 56.66 ? 264 LYS D NZ 1 +ATOM 11048 N N . GLN D 2 265 ? -58.253 -19.645 -95.187 1.00 68.29 ? 265 GLN D N 1 +ATOM 11049 C CA . GLN D 2 265 ? -58.316 -20.130 -96.561 1.00 69.63 ? 265 GLN D CA 1 +ATOM 11050 C C . GLN D 2 265 ? -59.371 -21.226 -96.691 1.00 69.63 ? 265 GLN D C 1 +ATOM 11051 O O . GLN D 2 265 ? -59.745 -21.880 -95.712 1.00 70.17 ? 265 GLN D O 1 +ATOM 11052 C CB . GLN D 2 265 ? -56.948 -20.652 -97.039 1.00 65.49 ? 265 GLN D CB 1 +ATOM 11053 C CG . GLN D 2 265 ? -56.303 -19.825 -98.141 1.00 66.59 ? 265 GLN D CG 1 +ATOM 11054 C CD . GLN D 2 265 ? -57.268 -19.548 -99.288 1.00 87.62 ? 265 GLN D CD 1 +ATOM 11055 O OE1 . GLN D 2 265 ? -58.114 -20.386 -99.625 1.00 83.39 ? 265 GLN D OE1 1 +ATOM 11056 N NE2 . GLN D 2 265 ? -57.145 -18.371 -99.896 1.00 85.86 ? 265 GLN D NE2 1 +ATOM 11057 N N . THR D 2 266 ? -59.830 -21.429 -97.930 1.00 63.29 ? 266 THR D N 1 +ATOM 11058 C CA . THR D 2 266 ? -60.901 -22.364 -98.251 1.00 56.63 ? 266 THR D CA 1 +ATOM 11059 C C . THR D 2 266 ? -60.374 -23.796 -98.314 1.00 62.26 ? 266 THR D C 1 +ATOM 11060 O O . THR D 2 266 ? -59.199 -24.072 -98.062 1.00 72.33 ? 266 THR D O 1 +ATOM 11061 C CB . THR D 2 266 ? -61.548 -21.994 -99.578 1.00 50.65 ? 266 THR D CB 1 +ATOM 11062 O OG1 . THR D 2 266 ? -60.630 -22.283 -100.639 1.00 48.50 ? 266 THR D OG1 1 +ATOM 11063 C CG2 . THR D 2 266 ? -61.895 -20.526 -99.596 1.00 58.77 ? 266 THR D CG2 1 +ATOM 11064 N N . ARG D 2 267 ? -61.253 -24.726 -98.681 1.00 59.11 ? 267 ARG D N 1 +ATOM 11065 C CA . ARG D 2 267 ? -60.892 -26.139 -98.684 1.00 57.98 ? 267 ARG D CA 1 +ATOM 11066 C C . ARG D 2 267 ? -60.247 -26.563 -100.000 1.00 57.63 ? 267 ARG D C 1 +ATOM 11067 O O . ARG D 2 267 ? -59.211 -27.235 -100.002 1.00 50.45 ? 267 ARG D O 1 +ATOM 11068 C CB . ARG D 2 267 ? -62.131 -26.997 -98.404 1.00 60.04 ? 267 ARG D CB 1 +ATOM 11069 C CG . ARG D 2 267 ? -62.319 -27.379 -96.938 1.00 59.13 ? 267 ARG D CG 1 +ATOM 11070 C CD . ARG D 2 267 ? -62.420 -26.142 -96.052 1.00 54.61 ? 267 ARG D CD 1 +ATOM 11071 N NE . ARG D 2 267 ? -62.825 -26.457 -94.685 1.00 52.93 ? 267 ARG D NE 1 +ATOM 11072 C CZ . ARG D 2 267 ? -64.085 -26.478 -94.261 1.00 57.57 ? 267 ARG D CZ 1 +ATOM 11073 N NH1 . ARG D 2 267 ? -65.079 -26.201 -95.094 1.00 63.01 ? 267 ARG D NH1 1 +ATOM 11074 N NH2 . ARG D 2 267 ? -64.355 -26.774 -93.000 1.00 55.67 ? 267 ARG D NH2 1 +ATOM 11075 N N . GLU D 2 268 ? -60.842 -26.164 -101.123 1.00 62.73 ? 268 GLU D N 1 +ATOM 11076 C CA . GLU D 2 268 ? -60.389 -26.601 -102.435 1.00 55.76 ? 268 GLU D CA 1 +ATOM 11077 C C . GLU D 2 268 ? -59.131 -25.884 -102.897 1.00 51.15 ? 268 GLU D C 1 +ATOM 11078 O O . GLU D 2 268 ? -58.691 -26.112 -104.029 1.00 50.38 ? 268 GLU D O 1 +ATOM 11079 C CB . GLU D 2 268 ? -61.494 -26.398 -103.482 1.00 57.34 ? 268 GLU D CB 1 +ATOM 11080 C CG . GLU D 2 268 ? -62.793 -27.155 -103.213 1.00 63.85 ? 268 GLU D CG 1 +ATOM 11081 C CD . GLU D 2 268 ? -63.751 -26.393 -102.311 1.00 68.50 ? 268 GLU D CD 1 +ATOM 11082 O OE1 . GLU D 2 268 ? -63.463 -25.218 -101.988 1.00 65.11 ? 268 GLU D OE1 1 +ATOM 11083 O OE2 . GLU D 2 268 ? -64.787 -26.977 -101.919 1.00 66.69 ? 268 GLU D OE2 1 +ATOM 11084 N N . GLN D 2 269 ? -58.545 -25.033 -102.063 1.00 54.49 ? 269 GLN D N 1 +ATOM 11085 C CA . GLN D 2 269 ? -57.372 -24.275 -102.460 1.00 60.94 ? 269 GLN D CA 1 +ATOM 11086 C C . GLN D 2 269 ? -56.086 -25.013 -102.101 1.00 58.99 ? 269 GLN D C 1 +ATOM 11087 O O . GLN D 2 269 ? -56.012 -25.730 -101.099 1.00 55.24 ? 269 GLN D O 1 +ATOM 11088 C CB . GLN D 2 269 ? -57.384 -22.890 -101.810 1.00 59.83 ? 269 GLN D CB 1 +ATOM 11089 C CG . GLN D 2 269 ? -58.032 -21.823 -102.677 1.00 66.42 ? 269 GLN D CG 1 +ATOM 11090 C CD . GLN D 2 269 ? -57.452 -20.446 -102.431 1.00 84.03 ? 269 GLN D CD 1 +ATOM 11091 O OE1 . GLN D 2 269 ? -56.278 -20.311 -102.079 1.00 88.46 ? 269 GLN D OE1 1 +ATOM 11092 N NE2 . GLN D 2 269 ? -58.269 -19.412 -102.616 1.00 90.38 ? 269 GLN D NE2 1 +ATOM 11093 N N . GLU D 2 270 ? -55.069 -24.831 -102.941 1.00 55.11 ? 270 GLU D N 1 +ATOM 11094 C CA . GLU D 2 270 ? -53.744 -25.384 -102.718 1.00 50.84 ? 270 GLU D CA 1 +ATOM 11095 C C . GLU D 2 270 ? -52.741 -24.255 -102.523 1.00 49.34 ? 270 GLU D C 1 +ATOM 11096 O O . GLU D 2 270 ? -52.878 -23.174 -103.101 1.00 46.80 ? 270 GLU D O 1 +ATOM 11097 C CB . GLU D 2 270 ? -53.289 -26.260 -103.891 1.00 53.81 ? 270 GLU D CB 1 +ATOM 11098 C CG . GLU D 2 270 ? -53.816 -27.688 -103.896 1.00 55.66 ? 270 GLU D CG 1 +ATOM 11099 C CD . GLU D 2 270 ? -52.981 -28.603 -104.782 1.00 64.92 ? 270 GLU D CD 1 +ATOM 11100 O OE1 . GLU D 2 270 ? -51.747 -28.649 -104.588 1.00 70.42 ? 270 GLU D OE1 1 +ATOM 11101 O OE2 . GLU D 2 270 ? -53.548 -29.255 -105.687 1.00 64.06 ? 270 GLU D OE2 1 +ATOM 11102 N N . THR D 2 271 ? -51.722 -24.529 -101.720 1.00 48.69 ? 271 THR D N 1 +ATOM 11103 C CA . THR D 2 271 ? -50.627 -23.588 -101.542 1.00 46.52 ? 271 THR D CA 1 +ATOM 11104 C C . THR D 2 271 ? -49.894 -23.371 -102.862 1.00 49.79 ? 271 THR D C 1 +ATOM 11105 O O . THR D 2 271 ? -49.565 -24.349 -103.548 1.00 56.72 ? 271 THR D O 1 +ATOM 11106 C CB . THR D 2 271 ? -49.653 -24.103 -100.488 1.00 46.28 ? 271 THR D CB 1 +ATOM 11107 O OG1 . THR D 2 271 ? -50.325 -24.205 -99.227 1.00 47.11 ? 271 THR D OG1 1 +ATOM 11108 C CG2 . THR D 2 271 ? -48.470 -23.168 -100.361 1.00 49.12 ? 271 THR D CG2 1 +ATOM 11109 N N . PRO D 2 272 ? -49.645 -22.126 -103.263 1.00 48.43 ? 272 PRO D N 1 +ATOM 11110 C CA . PRO D 2 272 ? -48.902 -21.866 -104.504 1.00 52.43 ? 272 PRO D CA 1 +ATOM 11111 C C . PRO D 2 272 ? -47.570 -22.595 -104.511 1.00 55.41 ? 272 PRO D C 1 +ATOM 11112 O O . PRO D 2 272 ? -46.900 -22.702 -103.472 1.00 52.59 ? 272 PRO D O 1 +ATOM 11113 C CB . PRO D 2 272 ? -48.705 -20.344 -104.481 1.00 51.92 ? 272 PRO D CB 1 +ATOM 11114 C CG . PRO D 2 272 ? -49.845 -19.841 -103.667 1.00 47.21 ? 272 PRO D CG 1 +ATOM 11115 C CD . PRO D 2 272 ? -50.108 -20.883 -102.624 1.00 47.41 ? 272 PRO D CD 1 +ATOM 11116 N N . PRO D 2 273 ? -47.159 -23.129 -105.663 1.00 54.14 ? 273 PRO D N 1 +ATOM 11117 C CA . PRO D 2 273 ? -45.906 -23.898 -105.707 1.00 51.70 ? 273 PRO D CA 1 +ATOM 11118 C C . PRO D 2 273 ? -44.681 -23.067 -105.388 1.00 51.19 ? 273 PRO D C 1 +ATOM 11119 O O . PRO D 2 273 ? -43.667 -23.625 -104.950 1.00 50.90 ? 273 PRO D O 1 +ATOM 11120 C CB . PRO D 2 273 ? -45.867 -24.425 -107.149 1.00 60.75 ? 273 PRO D CB 1 +ATOM 11121 C CG . PRO D 2 273 ? -47.280 -24.306 -107.655 1.00 60.49 ? 273 PRO D CG 1 +ATOM 11122 C CD . PRO D 2 273 ? -47.835 -23.099 -106.970 1.00 58.36 ? 273 PRO D CD 1 +ATOM 11123 N N . ASP D 2 274 ? -44.748 -21.751 -105.572 1.00 51.54 ? 274 ASP D N 1 +ATOM 11124 C CA . ASP D 2 274 ? -43.613 -20.862 -105.370 1.00 51.28 ? 274 ASP D CA 1 +ATOM 11125 C C . ASP D 2 274 ? -43.506 -20.357 -103.939 1.00 48.82 ? 274 ASP D C 1 +ATOM 11126 O O . ASP D 2 274 ? -42.626 -19.542 -103.645 1.00 43.14 ? 274 ASP D O 1 +ATOM 11127 C CB . ASP D 2 274 ? -43.720 -19.667 -106.318 1.00 49.69 ? 274 ASP D CB 1 +ATOM 11128 C CG . ASP D 2 274 ? -44.074 -20.076 -107.725 1.00 52.37 ? 274 ASP D CG 1 +ATOM 11129 O OD1 . ASP D 2 274 ? -45.262 -20.387 -107.969 1.00 52.37 ? 274 ASP D OD1 1 +ATOM 11130 O OD2 . ASP D 2 274 ? -43.170 -20.082 -108.584 1.00 55.23 ? 274 ASP D OD2 1 +ATOM 11131 N N . PHE D 2 275 ? -44.358 -20.842 -103.040 1.00 50.33 ? 275 PHE D N 1 +ATOM 11132 C CA . PHE D 2 275 ? -44.360 -20.395 -101.655 1.00 51.30 ? 275 PHE D CA 1 +ATOM 11133 C C . PHE D 2 275 ? -43.344 -21.192 -100.856 1.00 51.37 ? 275 PHE D C 1 +ATOM 11134 O O . PHE D 2 275 ? -43.322 -22.424 -100.924 1.00 54.13 ? 275 PHE D O 1 +ATOM 11135 C CB . PHE D 2 275 ? -45.747 -20.559 -101.034 1.00 50.14 ? 275 PHE D CB 1 +ATOM 11136 C CG . PHE D 2 275 ? -46.629 -19.354 -101.187 1.00 49.31 ? 275 PHE D CG 1 +ATOM 11137 C CD1 . PHE D 2 275 ? -46.220 -18.272 -101.948 1.00 51.84 ? 275 PHE D CD1 1 +ATOM 11138 C CD2 . PHE D 2 275 ? -47.867 -19.305 -100.573 1.00 46.01 ? 275 PHE D CD2 1 +ATOM 11139 C CE1 . PHE D 2 275 ? -47.029 -17.166 -102.092 1.00 52.60 ? 275 PHE D CE1 1 +ATOM 11140 C CE2 . PHE D 2 275 ? -48.681 -18.205 -100.714 1.00 47.26 ? 275 PHE D CE2 1 +ATOM 11141 C CZ . PHE D 2 275 ? -48.263 -17.133 -101.473 1.00 54.25 ? 275 PHE D CZ 1 +ATOM 11142 N N . PHE D 2 276 ? -42.510 -20.486 -100.100 1.00 49.19 ? 276 PHE D N 1 +ATOM 11143 C CA . PHE D 2 276 ? -41.606 -21.160 -99.189 1.00 51.40 ? 276 PHE D CA 1 +ATOM 11144 C C . PHE D 2 276 ? -42.393 -21.824 -98.059 1.00 54.20 ? 276 PHE D C 1 +ATOM 11145 O O . PHE D 2 276 ? -43.565 -21.520 -97.816 1.00 55.17 ? 276 PHE D O 1 +ATOM 11146 C CB . PHE D 2 276 ? -40.585 -20.173 -98.621 1.00 52.46 ? 276 PHE D CB 1 +ATOM 11147 C CG . PHE D 2 276 ? -39.441 -19.860 -99.557 1.00 56.92 ? 276 PHE D CG 1 +ATOM 11148 C CD1 . PHE D 2 276 ? -38.410 -20.770 -99.745 1.00 57.48 ? 276 PHE D CD1 1 +ATOM 11149 C CD2 . PHE D 2 276 ? -39.384 -18.647 -100.231 1.00 56.67 ? 276 PHE D CD2 1 +ATOM 11150 C CE1 . PHE D 2 276 ? -37.352 -20.480 -100.595 1.00 55.07 ? 276 PHE D CE1 1 +ATOM 11151 C CE2 . PHE D 2 276 ? -38.324 -18.353 -101.083 1.00 52.34 ? 276 PHE D CE2 1 +ATOM 11152 C CZ . PHE D 2 276 ? -37.311 -19.272 -101.263 1.00 49.46 ? 276 PHE D CZ 1 +ATOM 11153 N N . TYR D 2 277 ? -41.728 -22.757 -97.371 1.00 55.12 ? 277 TYR D N 1 +ATOM 11154 C CA . TYR D 2 277 ? -42.345 -23.433 -96.233 1.00 54.10 ? 277 TYR D CA 1 +ATOM 11155 C C . TYR D 2 277 ? -42.698 -22.464 -95.116 1.00 50.65 ? 277 TYR D C 1 +ATOM 11156 O O . TYR D 2 277 ? -43.632 -22.718 -94.347 1.00 50.08 ? 277 TYR D O 1 +ATOM 11157 C CB . TYR D 2 277 ? -41.420 -24.530 -95.706 1.00 58.39 ? 277 TYR D CB 1 +ATOM 11158 C CG . TYR D 2 277 ? -39.948 -24.177 -95.748 1.00 68.33 ? 277 TYR D CG 1 +ATOM 11159 C CD1 . TYR D 2 277 ? -39.328 -23.517 -94.691 1.00 56.47 ? 277 TYR D CD1 1 +ATOM 11160 C CD2 . TYR D 2 277 ? -39.178 -24.499 -96.861 1.00 78.41 ? 277 TYR D CD2 1 +ATOM 11161 C CE1 . TYR D 2 277 ? -37.974 -23.200 -94.746 1.00 61.62 ? 277 TYR D CE1 1 +ATOM 11162 C CE2 . TYR D 2 277 ? -37.832 -24.183 -96.925 1.00 73.39 ? 277 TYR D CE2 1 +ATOM 11163 C CZ . TYR D 2 277 ? -37.234 -23.535 -95.867 1.00 72.57 ? 277 TYR D CZ 1 +ATOM 11164 O OH . TYR D 2 277 ? -35.894 -23.228 -95.944 1.00 74.97 ? 277 TYR D OH 1 +ATOM 11165 N N . PHE D 2 278 ? -41.961 -21.365 -94.997 1.00 55.76 ? 278 PHE D N 1 +ATOM 11166 C CA . PHE D 2 278 ? -42.252 -20.351 -93.996 1.00 58.17 ? 278 PHE D CA 1 +ATOM 11167 C C . PHE D 2 278 ? -43.202 -19.275 -94.499 1.00 51.69 ? 278 PHE D C 1 +ATOM 11168 O O . PHE D 2 278 ? -43.359 -18.249 -93.835 1.00 53.81 ? 278 PHE D O 1 +ATOM 11169 C CB . PHE D 2 278 ? -40.955 -19.706 -93.497 1.00 62.32 ? 278 PHE D CB 1 +ATOM 11170 C CG . PHE D 2 278 ? -40.102 -19.108 -94.587 1.00 58.82 ? 278 PHE D CG 1 +ATOM 11171 C CD1 . PHE D 2 278 ? -40.294 -17.800 -95.006 1.00 53.79 ? 278 PHE D CD1 1 +ATOM 11172 C CD2 . PHE D 2 278 ? -39.088 -19.850 -95.173 1.00 62.39 ? 278 PHE D CD2 1 +ATOM 11173 C CE1 . PHE D 2 278 ? -39.502 -17.252 -95.998 1.00 57.94 ? 278 PHE D CE1 1 +ATOM 11174 C CE2 . PHE D 2 278 ? -38.292 -19.306 -96.163 1.00 61.74 ? 278 PHE D CE2 1 +ATOM 11175 C CZ . PHE D 2 278 ? -38.499 -18.008 -96.576 1.00 65.82 ? 278 PHE D CZ 1 +ATOM 11176 N N . SER D 2 279 ? -43.839 -19.482 -95.648 1.00 50.66 ? 279 SER D N 1 +ATOM 11177 C CA . SER D 2 279 ? -44.844 -18.556 -96.141 1.00 48.39 ? 279 SER D CA 1 +ATOM 11178 C C . SER D 2 279 ? -46.227 -19.172 -96.234 1.00 51.52 ? 279 SER D C 1 +ATOM 11179 O O . SER D 2 279 ? -47.181 -18.462 -96.574 1.00 53.72 ? 279 SER D O 1 +ATOM 11180 C CB . SER D 2 279 ? -44.439 -18.015 -97.516 1.00 54.78 ? 279 SER D CB 1 +ATOM 11181 O OG . SER D 2 279 ? -43.211 -17.316 -97.436 1.00 69.16 ? 279 SER D OG 1 +ATOM 11182 N N . ASP D 2 280 ? -46.363 -20.465 -95.958 1.00 52.82 ? 280 ASP D N 1 +ATOM 11183 C CA . ASP D 2 280 ? -47.649 -21.133 -96.066 1.00 52.72 ? 280 ASP D CA 1 +ATOM 11184 C C . ASP D 2 280 ? -48.607 -20.633 -94.985 1.00 53.12 ? 280 ASP D C 1 +ATOM 11185 O O . ASP D 2 280 ? -48.199 -20.129 -93.935 1.00 51.73 ? 280 ASP D O 1 +ATOM 11186 C CB . ASP D 2 280 ? -47.476 -22.647 -95.962 1.00 51.86 ? 280 ASP D CB 1 +ATOM 11187 C CG . ASP D 2 280 ? -48.584 -23.409 -96.666 1.00 55.16 ? 280 ASP D CG 1 +ATOM 11188 O OD1 . ASP D 2 280 ? -49.738 -22.922 -96.684 1.00 51.06 ? 280 ASP D OD1 1 +ATOM 11189 O OD2 . ASP D 2 280 ? -48.301 -24.507 -97.189 1.00 57.79 ? 280 ASP D OD2 1 +ATOM 11190 N N . PHE D 2 281 ? -49.900 -20.772 -95.262 1.00 52.56 ? 281 PHE D N 1 +ATOM 11191 C CA . PHE D 2 281 ? -50.928 -20.347 -94.325 1.00 56.28 ? 281 PHE D CA 1 +ATOM 11192 C C . PHE D 2 281 ? -51.112 -21.365 -93.202 1.00 55.83 ? 281 PHE D C 1 +ATOM 11193 O O . PHE D 2 281 ? -50.948 -22.574 -93.393 1.00 56.75 ? 281 PHE D O 1 +ATOM 11194 C CB . PHE D 2 281 ? -52.264 -20.154 -95.043 1.00 59.70 ? 281 PHE D CB 1 +ATOM 11195 C CG . PHE D 2 281 ? -52.264 -19.039 -96.047 1.00 66.67 ? 281 PHE D CG 1 +ATOM 11196 C CD1 . PHE D 2 281 ? -52.075 -17.729 -95.643 1.00 68.48 ? 281 PHE D CD1 1 +ATOM 11197 C CD2 . PHE D 2 281 ? -52.513 -19.293 -97.386 1.00 64.13 ? 281 PHE D CD2 1 +ATOM 11198 C CE1 . PHE D 2 281 ? -52.094 -16.698 -96.561 1.00 66.63 ? 281 PHE D CE1 1 +ATOM 11199 C CE2 . PHE D 2 281 ? -52.536 -18.265 -98.307 1.00 60.40 ? 281 PHE D CE2 1 +ATOM 11200 C CZ . PHE D 2 281 ? -52.326 -16.967 -97.893 1.00 63.06 ? 281 PHE D CZ 1 +ATOM 11201 N N . GLU D 2 282 ? -51.473 -20.865 -92.022 1.00 55.37 ? 282 GLU D N 1 +ATOM 11202 C CA . GLU D 2 282 ? -51.914 -21.715 -90.921 1.00 52.37 ? 282 GLU D CA 1 +ATOM 11203 C C . GLU D 2 282 ? -53.432 -21.801 -90.994 1.00 51.50 ? 282 GLU D C 1 +ATOM 11204 O O . GLU D 2 282 ? -54.124 -20.793 -90.818 1.00 57.00 ? 282 GLU D O 1 +ATOM 11205 C CB . GLU D 2 282 ? -51.457 -21.159 -89.573 1.00 51.81 ? 282 GLU D CB 1 +ATOM 11206 C CG . GLU D 2 282 ? -49.956 -21.271 -89.326 1.00 59.76 ? 282 GLU D CG 1 +ATOM 11207 C CD . GLU D 2 282 ? -49.576 -21.051 -87.872 1.00 62.31 ? 282 GLU D CD 1 +ATOM 11208 O OE1 . GLU D 2 282 ? -50.175 -20.168 -87.226 1.00 69.35 ? 282 GLU D OE1 1 +ATOM 11209 O OE2 . GLU D 2 282 ? -48.662 -21.748 -87.382 1.00 69.33 ? 282 GLU D OE2 1 +ATOM 11210 N N . ARG D 2 283 ? -53.955 -22.991 -91.271 1.00 44.42 ? 283 ARG D N 1 +ATOM 11211 C CA . ARG D 2 283 ? -55.380 -23.159 -91.510 1.00 48.93 ? 283 ARG D CA 1 +ATOM 11212 C C . ARG D 2 283 ? -56.009 -24.080 -90.472 1.00 47.60 ? 283 ARG D C 1 +ATOM 11213 O O . ARG D 2 283 ? -55.383 -25.041 -90.014 1.00 46.03 ? 283 ARG D O 1 +ATOM 11214 C CB . ARG D 2 283 ? -55.635 -23.694 -92.919 1.00 54.16 ? 283 ARG D CB 1 +ATOM 11215 C CG . ARG D 2 283 ? -55.124 -25.091 -93.163 1.00 55.29 ? 283 ARG D CG 1 +ATOM 11216 C CD . ARG D 2 283 ? -54.556 -25.225 -94.567 1.00 57.33 ? 283 ARG D CD 1 +ATOM 11217 N NE . ARG D 2 283 ? -53.096 -25.223 -94.584 1.00 51.09 ? 283 ARG D NE 1 +ATOM 11218 C CZ . ARG D 2 283 ? -52.363 -24.941 -95.655 1.00 48.13 ? 283 ARG D CZ 1 +ATOM 11219 N NH1 . ARG D 2 283 ? -52.951 -24.620 -96.799 1.00 56.42 ? 283 ARG D NH1 1 +ATOM 11220 N NH2 . ARG D 2 283 ? -51.042 -24.980 -95.581 1.00 43.91 ? 283 ARG D NH2 1 +ATOM 11221 N N . HIS D 2 284 ? -57.255 -23.762 -90.102 1.00 48.29 ? 284 HIS D N 1 +ATOM 11222 C CA . HIS D 2 284 ? -57.999 -24.583 -89.152 1.00 46.21 ? 284 HIS D CA 1 +ATOM 11223 C C . HIS D 2 284 ? -58.188 -26.007 -89.649 1.00 48.87 ? 284 HIS D C 1 +ATOM 11224 O O . HIS D 2 284 ? -58.262 -26.935 -88.836 1.00 49.06 ? 284 HIS D O 1 +ATOM 11225 C CB . HIS D 2 284 ? -59.364 -23.958 -88.856 1.00 48.42 ? 284 HIS D CB 1 +ATOM 11226 C CG . HIS D 2 284 ? -60.262 -23.850 -90.052 1.00 53.74 ? 284 HIS D CG 1 +ATOM 11227 N ND1 . HIS D 2 284 ? -59.805 -23.498 -91.305 1.00 53.41 ? 284 HIS D ND1 1 +ATOM 11228 C CD2 . HIS D 2 284 ? -61.594 -24.059 -90.185 1.00 56.64 ? 284 HIS D CD2 1 +ATOM 11229 C CE1 . HIS D 2 284 ? -60.818 -23.482 -92.153 1.00 56.81 ? 284 HIS D CE1 1 +ATOM 11230 N NE2 . HIS D 2 284 ? -61.915 -23.821 -91.499 1.00 55.90 ? 284 HIS D NE2 1 +ATOM 11231 N N . ASN D 2 285 ? -58.274 -26.197 -90.970 1.00 49.40 ? 285 ASN D N 1 +ATOM 11232 C CA . ASN D 2 285 ? -58.386 -27.542 -91.529 1.00 46.94 ? 285 ASN D CA 1 +ATOM 11233 C C . ASN D 2 285 ? -57.306 -28.449 -90.965 1.00 50.96 ? 285 ASN D C 1 +ATOM 11234 O O . ASN D 2 285 ? -57.588 -29.543 -90.463 1.00 51.97 ? 285 ASN D O 1 +ATOM 11235 C CB . ASN D 2 285 ? -58.273 -27.496 -93.054 1.00 48.06 ? 285 ASN D CB 1 +ATOM 11236 C CG . ASN D 2 285 ? -59.120 -26.412 -93.676 1.00 65.58 ? 285 ASN D CG 1 +ATOM 11237 O OD1 . ASN D 2 285 ? -60.308 -26.291 -93.376 1.00 79.68 ? 285 ASN D OD1 1 +ATOM 11238 N ND2 . ASN D 2 285 ? -58.512 -25.609 -94.549 1.00 58.38 ? 285 ASN D ND2 1 +ATOM 11239 N N . ALA D 2 286 ? -56.056 -27.985 -91.008 1.00 50.25 ? 286 ALA D N 1 +ATOM 11240 C CA . ALA D 2 286 ? -54.943 -28.829 -90.600 1.00 47.81 ? 286 ALA D CA 1 +ATOM 11241 C C . ALA D 2 286 ? -55.003 -29.135 -89.114 1.00 48.47 ? 286 ALA D C 1 +ATOM 11242 O O . ALA D 2 286 ? -54.778 -30.279 -88.705 1.00 50.89 ? 286 ALA D O 1 +ATOM 11243 C CB . ALA D 2 286 ? -53.619 -28.156 -90.953 1.00 49.19 ? 286 ALA D CB 1 +ATOM 11244 N N . GLU D 2 287 ? -55.320 -28.132 -88.293 1.00 46.66 ? 287 GLU D N 1 +ATOM 11245 C CA . GLU D 2 287 ? -55.341 -28.345 -86.850 1.00 50.80 ? 287 GLU D CA 1 +ATOM 11246 C C . GLU D 2 287 ? -56.337 -29.435 -86.468 1.00 48.59 ? 287 GLU D C 1 +ATOM 11247 O O . GLU D 2 287 ? -55.996 -30.370 -85.735 1.00 44.03 ? 287 GLU D O 1 +ATOM 11248 C CB . GLU D 2 287 ? -55.642 -27.030 -86.129 1.00 51.98 ? 287 GLU D CB 1 +ATOM 11249 C CG . GLU D 2 287 ? -54.530 -25.981 -86.244 1.00 53.30 ? 287 GLU D CG 1 +ATOM 11250 C CD . GLU D 2 287 ? -53.310 -26.290 -85.369 1.00 61.15 ? 287 GLU D CD 1 +ATOM 11251 O OE1 . GLU D 2 287 ? -53.373 -27.234 -84.550 1.00 62.14 ? 287 GLU D OE1 1 +ATOM 11252 O OE2 . GLU D 2 287 ? -52.288 -25.576 -85.488 1.00 59.23 ? 287 GLU D OE2 1 +ATOM 11253 N N . ILE D 2 288 ? -57.569 -29.346 -86.975 1.00 45.76 ? 288 ILE D N 1 +ATOM 11254 C CA . ILE D 2 288 ? -58.574 -30.352 -86.648 1.00 43.61 ? 288 ILE D CA 1 +ATOM 11255 C C . ILE D 2 288 ? -58.204 -31.705 -87.237 1.00 49.77 ? 288 ILE D C 1 +ATOM 11256 O O . ILE D 2 288 ? -58.347 -32.741 -86.578 1.00 55.82 ? 288 ILE D O 1 +ATOM 11257 C CB . ILE D 2 288 ? -59.960 -29.903 -87.128 1.00 42.20 ? 288 ILE D CB 1 +ATOM 11258 C CG1 . ILE D 2 288 ? -60.235 -28.480 -86.666 1.00 48.70 ? 288 ILE D CG1 1 +ATOM 11259 C CG2 . ILE D 2 288 ? -61.019 -30.844 -86.606 1.00 47.83 ? 288 ILE D CG2 1 +ATOM 11260 C CD1 . ILE D 2 288 ? -61.443 -27.879 -87.319 1.00 54.05 ? 288 ILE D CD1 1 +ATOM 11261 N N . ALA D 2 289 ? -57.750 -31.727 -88.491 1.00 48.21 ? 289 ALA D N 1 +ATOM 11262 C CA . ALA D 2 289 ? -57.385 -32.998 -89.106 1.00 48.78 ? 289 ALA D CA 1 +ATOM 11263 C C . ALA D 2 289 ? -56.199 -33.642 -88.398 1.00 51.38 ? 289 ALA D C 1 +ATOM 11264 O O . ALA D 2 289 ? -56.148 -34.872 -88.269 1.00 51.31 ? 289 ALA D O 1 +ATOM 11265 C CB . ALA D 2 289 ? -57.076 -32.797 -90.588 1.00 44.70 ? 289 ALA D CB 1 +ATOM 11266 N N . ALA D 2 290 ? -55.253 -32.830 -87.913 1.00 46.95 ? 290 ALA D N 1 +ATOM 11267 C CA . ALA D 2 290 ? -54.072 -33.368 -87.243 1.00 43.29 ? 290 ALA D CA 1 +ATOM 11268 C C . ALA D 2 290 ? -54.450 -34.134 -85.986 1.00 47.63 ? 290 ALA D C 1 +ATOM 11269 O O . ALA D 2 290 ? -53.819 -35.144 -85.653 1.00 50.86 ? 290 ALA D O 1 +ATOM 11270 C CB . ALA D 2 290 ? -53.100 -32.242 -86.901 1.00 44.70 ? 290 ALA D CB 1 +ATOM 11271 N N . PHE D 2 291 ? -55.467 -33.661 -85.267 1.00 48.86 ? 291 PHE D N 1 +ATOM 11272 C CA . PHE D 2 291 ? -55.879 -34.330 -84.039 1.00 47.47 ? 291 PHE D CA 1 +ATOM 11273 C C . PHE D 2 291 ? -56.419 -35.722 -84.331 1.00 52.69 ? 291 PHE D C 1 +ATOM 11274 O O . PHE D 2 291 ? -56.051 -36.693 -83.660 1.00 61.16 ? 291 PHE D O 1 +ATOM 11275 C CB . PHE D 2 291 ? -56.919 -33.487 -83.311 1.00 46.65 ? 291 PHE D CB 1 +ATOM 11276 C CG . PHE D 2 291 ? -57.601 -34.206 -82.199 1.00 48.52 ? 291 PHE D CG 1 +ATOM 11277 C CD1 . PHE D 2 291 ? -56.908 -34.549 -81.054 1.00 55.85 ? 291 PHE D CD1 1 +ATOM 11278 C CD2 . PHE D 2 291 ? -58.942 -34.531 -82.291 1.00 56.33 ? 291 PHE D CD2 1 +ATOM 11279 C CE1 . PHE D 2 291 ? -57.535 -35.214 -80.022 1.00 62.62 ? 291 PHE D CE1 1 +ATOM 11280 C CE2 . PHE D 2 291 ? -59.579 -35.193 -81.263 1.00 61.54 ? 291 PHE D CE2 1 +ATOM 11281 C CZ . PHE D 2 291 ? -58.874 -35.535 -80.124 1.00 66.95 ? 291 PHE D CZ 1 +ATOM 11282 N N . HIS D 2 292 ? -57.287 -35.841 -85.337 1.00 51.22 ? 292 HIS D N 1 +ATOM 11283 C CA . HIS D 2 292 ? -57.829 -37.150 -85.684 1.00 54.04 ? 292 HIS D CA 1 +ATOM 11284 C C . HIS D 2 292 ? -56.762 -38.054 -86.289 1.00 53.47 ? 292 HIS D C 1 +ATOM 11285 O O . HIS D 2 292 ? -56.734 -39.257 -86.009 1.00 53.27 ? 292 HIS D O 1 +ATOM 11286 C CB . HIS D 2 292 ? -59.011 -36.989 -86.638 1.00 60.98 ? 292 HIS D CB 1 +ATOM 11287 C CG . HIS D 2 292 ? -60.221 -36.384 -85.997 1.00 68.03 ? 292 HIS D CG 1 +ATOM 11288 N ND1 . HIS D 2 292 ? -60.415 -35.023 -85.903 1.00 65.10 ? 292 HIS D ND1 1 +ATOM 11289 C CD2 . HIS D 2 292 ? -61.294 -36.959 -85.404 1.00 72.30 ? 292 HIS D CD2 1 +ATOM 11290 C CE1 . HIS D 2 292 ? -61.560 -34.785 -85.289 1.00 66.59 ? 292 HIS D CE1 1 +ATOM 11291 N NE2 . HIS D 2 292 ? -62.113 -35.943 -84.975 1.00 76.88 ? 292 HIS D NE2 1 +ATOM 11292 N N . LEU D 2 293 ? -55.873 -37.491 -87.115 1.00 52.01 ? 293 LEU D N 1 +ATOM 11293 C CA . LEU D 2 293 ? -54.768 -38.264 -87.682 1.00 50.59 ? 293 LEU D CA 1 +ATOM 11294 C C . LEU D 2 293 ? -53.887 -38.852 -86.587 1.00 48.66 ? 293 LEU D C 1 +ATOM 11295 O O . LEU D 2 293 ? -53.508 -40.027 -86.639 1.00 49.48 ? 293 LEU D O 1 +ATOM 11296 C CB . LEU D 2 293 ? -53.944 -37.376 -88.616 1.00 46.68 ? 293 LEU D CB 1 +ATOM 11297 C CG . LEU D 2 293 ? -53.017 -37.986 -89.676 1.00 42.85 ? 293 LEU D CG 1 +ATOM 11298 C CD1 . LEU D 2 293 ? -51.842 -38.753 -89.094 1.00 45.60 ? 293 LEU D CD1 1 +ATOM 11299 C CD2 . LEU D 2 293 ? -53.810 -38.875 -90.599 1.00 46.03 ? 293 LEU D CD2 1 +ATOM 11300 N N . ASP D 2 294 ? -53.510 -38.026 -85.613 1.00 47.77 ? 294 ASP D N 1 +ATOM 11301 C CA . ASP D 2 294 ? -52.701 -38.503 -84.500 1.00 49.21 ? 294 ASP D CA 1 +ATOM 11302 C C . ASP D 2 294 ? -53.469 -39.510 -83.651 1.00 49.71 ? 294 ASP D C 1 +ATOM 11303 O O . ASP D 2 294 ? -52.893 -40.479 -83.143 1.00 51.79 ? 294 ASP D O 1 +ATOM 11304 C CB . ASP D 2 294 ? -52.238 -37.307 -83.670 1.00 54.60 ? 294 ASP D CB 1 +ATOM 11305 C CG . ASP D 2 294 ? -51.601 -37.709 -82.364 1.00 58.09 ? 294 ASP D CG 1 +ATOM 11306 O OD1 . ASP D 2 294 ? -52.349 -38.060 -81.426 1.00 59.66 ? 294 ASP D OD1 1 +ATOM 11307 O OD2 . ASP D 2 294 ? -50.354 -37.678 -82.282 1.00 57.83 ? 294 ASP D OD2 1 +ATOM 11308 N N . ARG D 2 295 ? -54.771 -39.288 -83.481 1.00 48.82 ? 295 ARG D N 1 +ATOM 11309 C CA . ARG D 2 295 ? -55.596 -40.230 -82.734 1.00 53.24 ? 295 ARG D CA 1 +ATOM 11310 C C . ARG D 2 295 ? -55.672 -41.578 -83.442 1.00 53.64 ? 295 ARG D C 1 +ATOM 11311 O O . ARG D 2 295 ? -55.612 -42.632 -82.797 1.00 52.45 ? 295 ARG D O 1 +ATOM 11312 C CB . ARG D 2 295 ? -56.988 -39.632 -82.540 1.00 53.85 ? 295 ARG D CB 1 +ATOM 11313 C CG . ARG D 2 295 ? -58.050 -40.609 -82.111 1.00 54.51 ? 295 ARG D CG 1 +ATOM 11314 C CD . ARG D 2 295 ? -59.423 -40.021 -82.337 1.00 57.34 ? 295 ARG D CD 1 +ATOM 11315 N NE . ARG D 2 295 ? -59.926 -39.356 -81.141 1.00 67.39 ? 295 ARG D NE 1 +ATOM 11316 C CZ . ARG D 2 295 ? -60.969 -38.532 -81.129 1.00 76.54 ? 295 ARG D CZ 1 +ATOM 11317 N NH1 . ARG D 2 295 ? -61.618 -38.261 -82.254 1.00 69.68 ? 295 ARG D NH1 1 +ATOM 11318 N NH2 . ARG D 2 295 ? -61.365 -37.979 -79.990 1.00 73.51 ? 295 ARG D NH2 1 +ATOM 11319 N N . ILE D 2 296 ? -55.785 -41.560 -84.771 1.00 54.75 ? 296 ILE D N 1 +ATOM 11320 C CA . ILE D 2 296 ? -55.921 -42.796 -85.537 1.00 53.19 ? 296 ILE D CA 1 +ATOM 11321 C C . ILE D 2 296 ? -54.639 -43.617 -85.458 1.00 52.10 ? 296 ILE D C 1 +ATOM 11322 O O . ILE D 2 296 ? -54.679 -44.851 -85.412 1.00 58.16 ? 296 ILE D O 1 +ATOM 11323 C CB . ILE D 2 296 ? -56.307 -42.479 -86.994 1.00 50.89 ? 296 ILE D CB 1 +ATOM 11324 C CG1 . ILE D 2 296 ? -57.824 -42.573 -87.194 1.00 53.67 ? 296 ILE D CG1 1 +ATOM 11325 C CG2 . ILE D 2 296 ? -55.575 -43.403 -87.971 1.00 48.97 ? 296 ILE D CG2 1 +ATOM 11326 C CD1 . ILE D 2 296 ? -58.635 -41.658 -86.287 1.00 54.14 ? 296 ILE D CD1 1 +ATOM 11327 N N . LEU D 2 297 ? -53.483 -42.953 -85.428 1.00 47.32 ? 297 LEU D N 1 +ATOM 11328 C CA . LEU D 2 297 ? -52.219 -43.659 -85.269 1.00 42.43 ? 297 LEU D CA 1 +ATOM 11329 C C . LEU D 2 297 ? -51.930 -44.029 -83.826 1.00 51.34 ? 297 LEU D C 1 +ATOM 11330 O O . LEU D 2 297 ? -50.846 -44.553 -83.544 1.00 51.81 ? 297 LEU D O 1 +ATOM 11331 C CB . LEU D 2 297 ? -51.063 -42.825 -85.816 1.00 42.79 ? 297 LEU D CB 1 +ATOM 11332 C CG . LEU D 2 297 ? -51.215 -42.374 -87.261 1.00 43.12 ? 297 LEU D CG 1 +ATOM 11333 C CD1 . LEU D 2 297 ? -50.007 -41.561 -87.678 1.00 40.94 ? 297 LEU D CD1 1 +ATOM 11334 C CD2 . LEU D 2 297 ? -51.393 -43.583 -88.156 1.00 44.75 ? 297 LEU D CD2 1 +ATOM 11335 N N . ASP D 2 298 ? -52.862 -43.754 -82.912 1.00 60.10 ? 298 ASP D N 1 +ATOM 11336 C CA . ASP D 2 298 ? -52.713 -44.095 -81.500 1.00 62.43 ? 298 ASP D CA 1 +ATOM 11337 C C . ASP D 2 298 ? -51.448 -43.495 -80.900 1.00 59.91 ? 298 ASP D C 1 +ATOM 11338 O O . ASP D 2 298 ? -50.822 -44.084 -80.013 1.00 57.97 ? 298 ASP D O 1 +ATOM 11339 C CB . ASP D 2 298 ? -52.735 -45.608 -81.285 1.00 62.45 ? 298 ASP D CB 1 +ATOM 11340 C CG . ASP D 2 298 ? -53.311 -45.979 -79.952 1.00 64.26 ? 298 ASP D CG 1 +ATOM 11341 O OD1 . ASP D 2 298 ? -54.535 -45.812 -79.771 1.00 60.95 ? 298 ASP D OD1 1 +ATOM 11342 O OD2 . ASP D 2 298 ? -52.527 -46.388 -79.073 1.00 65.24 ? 298 ASP D OD2 1 +ATOM 11343 N N . PHE D 2 299 ? -51.055 -42.329 -81.406 1.00 52.95 ? 299 PHE D N 1 +ATOM 11344 C CA . PHE D 2 299 ? -49.932 -41.596 -80.843 1.00 53.74 ? 299 PHE D CA 1 +ATOM 11345 C C . PHE D 2 299 ? -50.361 -40.808 -79.615 1.00 59.77 ? 299 PHE D C 1 +ATOM 11346 O O . PHE D 2 299 ? -49.679 -40.831 -78.583 1.00 57.84 ? 299 PHE D O 1 +ATOM 11347 C CB . PHE D 2 299 ? -49.341 -40.670 -81.899 1.00 53.42 ? 299 PHE D CB 1 +ATOM 11348 C CG . PHE D 2 299 ? -48.438 -41.360 -82.859 1.00 53.80 ? 299 PHE D CG 1 +ATOM 11349 C CD1 . PHE D 2 299 ? -47.733 -42.483 -82.470 1.00 53.78 ? 299 PHE D CD1 1 +ATOM 11350 C CD2 . PHE D 2 299 ? -48.298 -40.894 -84.153 1.00 49.93 ? 299 PHE D CD2 1 +ATOM 11351 C CE1 . PHE D 2 299 ? -46.897 -43.123 -83.348 1.00 54.61 ? 299 PHE D CE1 1 +ATOM 11352 C CE2 . PHE D 2 299 ? -47.463 -41.531 -85.039 1.00 49.14 ? 299 PHE D CE2 1 +ATOM 11353 C CZ . PHE D 2 299 ? -46.761 -42.650 -84.637 1.00 53.73 ? 299 PHE D CZ 1 +ATOM 11354 N N . ARG D 2 300 ? -51.479 -40.084 -79.733 1.00 61.35 ? 300 ARG D N 1 +ATOM 11355 C CA . ARG D 2 300 ? -52.068 -39.293 -78.652 1.00 57.07 ? 300 ARG D CA 1 +ATOM 11356 C C . ARG D 2 300 ? -51.052 -38.284 -78.109 1.00 54.03 ? 300 ARG D C 1 +ATOM 11357 O O . ARG D 2 300 ? -50.750 -38.233 -76.916 1.00 54.73 ? 300 ARG D O 1 +ATOM 11358 C CB . ARG D 2 300 ? -52.626 -40.206 -77.552 1.00 63.13 ? 300 ARG D CB 1 +ATOM 11359 C CG . ARG D 2 300 ? -53.850 -41.029 -77.979 1.00 53.16 ? 300 ARG D CG 1 +ATOM 11360 C CD . ARG D 2 300 ? -54.009 -42.302 -77.139 1.00 60.18 ? 300 ARG D CD 1 +ATOM 11361 N NE . ARG D 2 300 ? -52.766 -43.072 -77.038 1.00 70.77 ? 300 ARG D NE 1 +ATOM 11362 C CZ . ARG D 2 300 ? -52.546 -44.049 -76.158 1.00 66.85 ? 300 ARG D CZ 1 +ATOM 11363 N NH1 . ARG D 2 300 ? -53.485 -44.380 -75.284 1.00 65.39 ? 300 ARG D NH1 1 +ATOM 11364 N NH2 . ARG D 2 300 ? -51.380 -44.689 -76.140 1.00 59.50 ? 300 ARG D NH2 1 +ATOM 11365 N N . ARG D 2 301 ? -50.524 -37.478 -79.033 1.00 56.00 ? 301 ARG D N 1 +ATOM 11366 C CA . ARG D 2 301 ? -49.548 -36.440 -78.735 1.00 56.21 ? 301 ARG D CA 1 +ATOM 11367 C C . ARG D 2 301 ? -50.054 -35.045 -79.079 1.00 56.23 ? 301 ARG D C 1 +ATOM 11368 O O . ARG D 2 301 ? -49.283 -34.082 -78.981 1.00 54.28 ? 301 ARG D O 1 +ATOM 11369 C CB . ARG D 2 301 ? -48.241 -36.694 -79.503 1.00 51.40 ? 301 ARG D CB 1 +ATOM 11370 C CG . ARG D 2 301 ? -47.968 -38.151 -79.837 1.00 51.08 ? 301 ARG D CG 1 +ATOM 11371 C CD . ARG D 2 301 ? -47.231 -38.876 -78.733 1.00 56.75 ? 301 ARG D CD 1 +ATOM 11372 N NE . ARG D 2 301 ? -46.964 -40.267 -79.090 1.00 59.15 ? 301 ARG D NE 1 +ATOM 11373 C CZ . ARG D 2 301 ? -45.960 -40.659 -79.869 1.00 61.51 ? 301 ARG D CZ 1 +ATOM 11374 N NH1 . ARG D 2 301 ? -45.124 -39.764 -80.382 1.00 57.60 ? 301 ARG D NH1 1 +ATOM 11375 N NH2 . ARG D 2 301 ? -45.793 -41.947 -80.138 1.00 60.49 ? 301 ARG D NH2 1 +ATOM 11376 N N . VAL D 2 302 ? -51.300 -34.915 -79.526 1.00 54.02 ? 302 VAL D N 1 +ATOM 11377 C CA . VAL D 2 302 ? -51.856 -33.628 -79.937 1.00 49.41 ? 302 VAL D CA 1 +ATOM 11378 C C . VAL D 2 302 ? -52.931 -33.206 -78.944 1.00 52.00 ? 302 VAL D C 1 +ATOM 11379 O O . VAL D 2 302 ? -53.686 -34.056 -78.450 1.00 56.95 ? 302 VAL D O 1 +ATOM 11380 C CB . VAL D 2 302 ? -52.436 -33.696 -81.358 1.00 48.37 ? 302 VAL D CB 1 +ATOM 11381 C CG1 . VAL D 2 302 ? -51.332 -33.912 -82.365 1.00 51.60 ? 302 VAL D CG1 1 +ATOM 11382 C CG2 . VAL D 2 302 ? -53.468 -34.809 -81.454 1.00 45.94 ? 302 VAL D CG2 1 +ATOM 11383 N N . PRO D 2 303 ? -53.052 -31.919 -78.637 1.00 49.28 ? 303 PRO D N 1 +ATOM 11384 C CA . PRO D 2 303 ? -54.168 -31.459 -77.821 1.00 44.79 ? 303 PRO D CA 1 +ATOM 11385 C C . PRO D 2 303 ? -55.455 -31.502 -78.621 1.00 44.38 ? 303 PRO D C 1 +ATOM 11386 O O . PRO D 2 303 ? -55.461 -31.185 -79.821 1.00 47.21 ? 303 PRO D O 1 +ATOM 11387 C CB . PRO D 2 303 ? -53.773 -30.020 -77.463 1.00 45.66 ? 303 PRO D CB 1 +ATOM 11388 C CG . PRO D 2 303 ? -52.916 -29.589 -78.589 1.00 48.41 ? 303 PRO D CG 1 +ATOM 11389 C CD . PRO D 2 303 ? -52.158 -30.815 -79.025 1.00 50.37 ? 303 PRO D CD 1 +ATOM 11390 N N . PRO D 2 304 ? -56.560 -31.897 -77.997 1.00 40.59 ? 304 PRO D N 1 +ATOM 11391 C CA . PRO D 2 304 ? -57.831 -31.973 -78.725 1.00 46.13 ? 304 PRO D CA 1 +ATOM 11392 C C . PRO D 2 304 ? -58.241 -30.622 -79.294 1.00 48.99 ? 304 PRO D C 1 +ATOM 11393 O O . PRO D 2 304 ? -58.139 -29.588 -78.632 1.00 51.07 ? 304 PRO D O 1 +ATOM 11394 C CB . PRO D 2 304 ? -58.819 -32.456 -77.657 1.00 45.50 ? 304 PRO D CB 1 +ATOM 11395 C CG . PRO D 2 304 ? -57.962 -33.149 -76.644 1.00 50.48 ? 304 PRO D CG 1 +ATOM 11396 C CD . PRO D 2 304 ? -56.675 -32.387 -76.617 1.00 42.22 ? 304 PRO D CD 1 +ATOM 11397 N N . VAL D 2 305 ? -58.721 -30.643 -80.534 1.00 49.31 ? 305 VAL D N 1 +ATOM 11398 C CA . VAL D 2 305 ? -59.158 -29.438 -81.228 1.00 49.30 ? 305 VAL D CA 1 +ATOM 11399 C C . VAL D 2 305 ? -60.452 -29.755 -81.963 1.00 46.58 ? 305 VAL D C 1 +ATOM 11400 O O . VAL D 2 305 ? -60.604 -30.835 -82.542 1.00 46.34 ? 305 VAL D O 1 +ATOM 11401 C CB . VAL D 2 305 ? -58.066 -28.908 -82.185 1.00 49.44 ? 305 VAL D CB 1 +ATOM 11402 C CG1 . VAL D 2 305 ? -57.536 -30.017 -83.045 1.00 51.09 ? 305 VAL D CG1 1 +ATOM 11403 C CG2 . VAL D 2 305 ? -58.602 -27.780 -83.061 1.00 46.54 ? 305 VAL D CG2 1 +ATOM 11404 N N . ALA D 2 306 ? -61.396 -28.815 -81.916 1.00 48.91 ? 306 ALA D N 1 +ATOM 11405 C CA . ALA D 2 306 ? -62.696 -28.958 -82.556 1.00 57.64 ? 306 ALA D CA 1 +ATOM 11406 C C . ALA D 2 306 ? -63.041 -27.673 -83.293 1.00 54.23 ? 306 ALA D C 1 +ATOM 11407 O O . ALA D 2 306 ? -62.692 -26.575 -82.854 1.00 56.26 ? 306 ALA D O 1 +ATOM 11408 C CB . ALA D 2 306 ? -63.794 -29.281 -81.535 1.00 58.96 ? 306 ALA D CB 1 +ATOM 11409 N N . GLY D 2 307 ? -63.754 -27.817 -84.405 1.00 48.52 ? 307 GLY D N 1 +ATOM 11410 C CA . GLY D 2 307 ? -64.094 -26.679 -85.236 1.00 54.15 ? 307 GLY D CA 1 +ATOM 11411 C C . GLY D 2 307 ? -65.464 -26.123 -84.900 1.00 59.16 ? 307 GLY D C 1 +ATOM 11412 O O . GLY D 2 307 ? -66.381 -26.857 -84.543 1.00 60.42 ? 307 GLY D O 1 +ATOM 11413 N N . ARG D 2 308 ? -65.607 -24.801 -85.027 1.00 56.15 ? 308 ARG D N 1 +ATOM 11414 C CA . ARG D 2 308 ? -66.826 -24.132 -84.598 1.00 56.85 ? 308 ARG D CA 1 +ATOM 11415 C C . ARG D 2 308 ? -67.175 -22.990 -85.544 1.00 49.60 ? 308 ARG D C 1 +ATOM 11416 O O . ARG D 2 308 ? -66.291 -22.274 -86.019 1.00 48.63 ? 308 ARG D O 1 +ATOM 11417 C CB . ARG D 2 308 ? -66.672 -23.620 -83.159 1.00 58.09 ? 308 ARG D CB 1 +ATOM 11418 C CG . ARG D 2 308 ? -67.875 -22.891 -82.614 1.00 58.42 ? 308 ARG D CG 1 +ATOM 11419 C CD . ARG D 2 308 ? -67.634 -22.508 -81.176 1.00 54.99 ? 308 ARG D CD 1 +ATOM 11420 N NE . ARG D 2 308 ? -68.729 -21.717 -80.637 1.00 53.81 ? 308 ARG D NE 1 +ATOM 11421 C CZ . ARG D 2 308 ? -68.945 -21.554 -79.340 1.00 55.39 ? 308 ARG D CZ 1 +ATOM 11422 N NH1 . ARG D 2 308 ? -68.148 -22.142 -78.459 1.00 50.69 ? 308 ARG D NH1 1 +ATOM 11423 N NH2 . ARG D 2 308 ? -69.965 -20.819 -78.924 1.00 64.71 ? 308 ARG D NH2 1 +ATOM 11424 N N . LEU D 2 309 ? -68.467 -22.856 -85.847 1.00 48.67 ? 309 LEU D N 1 +ATOM 11425 C CA . LEU D 2 309 ? -68.983 -21.716 -86.604 1.00 49.68 ? 309 LEU D CA 1 +ATOM 11426 C C . LEU D 2 309 ? -69.239 -20.587 -85.618 1.00 56.38 ? 309 LEU D C 1 +ATOM 11427 O O . LEU D 2 309 ? -70.288 -20.539 -84.972 1.00 54.55 ? 309 LEU D O 1 +ATOM 11428 C CB . LEU D 2 309 ? -70.261 -22.088 -87.346 1.00 51.85 ? 309 LEU D CB 1 +ATOM 11429 C CG . LEU D 2 309 ? -70.146 -23.174 -88.416 1.00 61.43 ? 309 LEU D CG 1 +ATOM 11430 C CD1 . LEU D 2 309 ? -71.512 -23.603 -88.915 1.00 60.29 ? 309 LEU D CD1 1 +ATOM 11431 C CD2 . LEU D 2 309 ? -69.295 -22.681 -89.574 1.00 63.60 ? 309 LEU D CD2 1 +ATOM 11432 N N . VAL D 2 310 ? -68.289 -19.666 -85.498 1.00 59.82 ? 310 VAL D N 1 +ATOM 11433 C CA . VAL D 2 310 ? -68.375 -18.599 -84.508 1.00 63.12 ? 310 VAL D CA 1 +ATOM 11434 C C . VAL D 2 310 ? -68.937 -17.345 -85.163 1.00 66.53 ? 310 VAL D C 1 +ATOM 11435 O O . VAL D 2 310 ? -68.755 -17.102 -86.363 1.00 66.14 ? 310 VAL D O 1 +ATOM 11436 C CB . VAL D 2 310 ? -67.009 -18.317 -83.842 1.00 59.59 ? 310 VAL D CB 1 +ATOM 11437 C CG1 . VAL D 2 310 ? -66.423 -19.593 -83.249 1.00 56.84 ? 310 VAL D CG1 1 +ATOM 11438 C CG2 . VAL D 2 310 ? -66.042 -17.701 -84.838 1.00 57.42 ? 310 VAL D CG2 1 +ATOM 11439 N N . ASN D 2 311 ? -69.652 -16.553 -84.362 1.00 66.46 ? 311 ASN D N 1 +ATOM 11440 C CA . ASN D 2 311 ? -70.198 -15.267 -84.783 1.00 60.17 ? 311 ASN D CA 1 +ATOM 11441 C C . ASN D 2 311 ? -69.168 -14.190 -84.462 1.00 59.81 ? 311 ASN D C 1 +ATOM 11442 O O . ASN D 2 311 ? -68.815 -13.998 -83.294 1.00 62.24 ? 311 ASN D O 1 +ATOM 11443 C CB . ASN D 2 311 ? -71.529 -14.999 -84.072 1.00 62.00 ? 311 ASN D CB 1 +ATOM 11444 C CG . ASN D 2 311 ? -72.226 -13.726 -84.549 1.00 60.02 ? 311 ASN D CG 1 +ATOM 11445 O OD1 . ASN D 2 311 ? -71.583 -12.725 -84.855 1.00 61.36 ? 311 ASN D OD1 1 +ATOM 11446 N ND2 . ASN D 2 311 ? -73.557 -13.761 -84.592 1.00 55.33 ? 311 ASN D ND2 1 +ATOM 11447 N N . MET D 2 312 ? -68.681 -13.497 -85.493 1.00 59.24 ? 312 MET D N 1 +ATOM 11448 C CA . MET D 2 312 ? -67.652 -12.479 -85.292 1.00 59.93 ? 312 MET D CA 1 +ATOM 11449 C C . MET D 2 312 ? -68.187 -11.195 -84.677 1.00 57.41 ? 312 MET D C 1 +ATOM 11450 O O . MET D 2 312 ? -67.392 -10.298 -84.376 1.00 52.01 ? 312 MET D O 1 +ATOM 11451 C CB . MET D 2 312 ? -66.943 -12.185 -86.617 1.00 64.25 ? 312 MET D CB 1 +ATOM 11452 C CG . MET D 2 312 ? -67.842 -12.229 -87.839 1.00 63.84 ? 312 MET D CG 1 +ATOM 11453 S SD . MET D 2 312 ? -67.099 -11.502 -89.316 1.00 79.14 ? 312 MET D SD 1 +ATOM 11454 C CE . MET D 2 312 ? -65.410 -12.082 -89.174 1.00 54.45 ? 312 MET D CE 1 +ATOM 11455 N N . THR D 2 313 ? -69.499 -11.085 -84.472 1.00 60.71 ? 313 THR D N 1 +ATOM 11456 C CA . THR D 2 313 ? -70.074 -9.921 -83.807 1.00 58.09 ? 313 THR D CA 1 +ATOM 11457 C C . THR D 2 313 ? -70.172 -10.131 -82.299 1.00 64.00 ? 313 THR D C 1 +ATOM 11458 O O . THR D 2 313 ? -69.585 -9.370 -81.523 1.00 66.01 ? 313 THR D O 1 +ATOM 11459 C CB . THR D 2 313 ? -71.454 -9.600 -84.389 1.00 58.72 ? 313 THR D CB 1 +ATOM 11460 O OG1 . THR D 2 313 ? -71.315 -9.130 -85.736 1.00 52.52 ? 313 THR D OG1 1 +ATOM 11461 C CG2 . THR D 2 313 ? -72.145 -8.541 -83.549 1.00 66.21 ? 313 THR D CG2 1 +ATOM 11462 N N . ARG D 2 314 ? -70.902 -11.163 -81.870 1.00 66.13 ? 314 ARG D N 1 +ATOM 11463 C CA . ARG D 2 314 ? -71.140 -11.374 -80.448 1.00 72.25 ? 314 ARG D CA 1 +ATOM 11464 C C . ARG D 2 314 ? -70.106 -12.275 -79.792 1.00 67.18 ? 314 ARG D C 1 +ATOM 11465 O O . ARG D 2 314 ? -69.967 -12.243 -78.564 1.00 68.81 ? 314 ARG D O 1 +ATOM 11466 C CB . ARG D 2 314 ? -72.533 -11.974 -80.218 1.00 68.80 ? 314 ARG D CB 1 +ATOM 11467 C CG . ARG D 2 314 ? -72.704 -13.385 -80.743 1.00 61.78 ? 314 ARG D CG 1 +ATOM 11468 C CD . ARG D 2 314 ? -74.076 -13.925 -80.390 1.00 62.39 ? 314 ARG D CD 1 +ATOM 11469 N NE . ARG D 2 314 ? -74.235 -15.312 -80.814 1.00 73.12 ? 314 ARG D NE 1 +ATOM 11470 C CZ . ARG D 2 314 ? -73.881 -16.361 -80.080 1.00 71.66 ? 314 ARG D CZ 1 +ATOM 11471 N NH1 . ARG D 2 314 ? -74.058 -17.589 -80.548 1.00 74.47 ? 314 ARG D NH1 1 +ATOM 11472 N NH2 . ARG D 2 314 ? -73.355 -16.184 -78.877 1.00 69.34 ? 314 ARG D NH2 1 +ATOM 11473 N N . GLU D 2 315 ? -69.370 -13.064 -80.570 1.00 59.01 ? 315 GLU D N 1 +ATOM 11474 C CA . GLU D 2 315 ? -68.371 -13.952 -80.005 1.00 58.51 ? 315 GLU D CA 1 +ATOM 11475 C C . GLU D 2 315 ? -66.944 -13.471 -80.230 1.00 55.80 ? 315 GLU D C 1 +ATOM 11476 O O . GLU D 2 315 ? -66.019 -14.075 -79.682 1.00 61.57 ? 315 GLU D O 1 +ATOM 11477 C CB . GLU D 2 315 ? -68.534 -15.377 -80.569 1.00 64.42 ? 315 GLU D CB 1 +ATOM 11478 C CG . GLU D 2 315 ? -69.890 -16.031 -80.268 1.00 69.56 ? 315 GLU D CG 1 +ATOM 11479 C CD . GLU D 2 315 ? -69.917 -17.529 -80.579 1.00 75.07 ? 315 GLU D CD 1 +ATOM 11480 O OE1 . GLU D 2 315 ? -69.487 -18.325 -79.716 1.00 69.45 ? 315 GLU D OE1 1 +ATOM 11481 O OE2 . GLU D 2 315 ? -70.374 -17.914 -81.681 1.00 71.01 ? 315 GLU D OE2 1 +ATOM 11482 N N . ILE D 2 316 ? -66.733 -12.399 -80.995 1.00 55.51 ? 316 ILE D N 1 +ATOM 11483 C CA . ILE D 2 316 ? -65.379 -11.899 -81.222 1.00 60.83 ? 316 ILE D CA 1 +ATOM 11484 C C . ILE D 2 316 ? -65.286 -10.424 -80.851 1.00 65.17 ? 316 ILE D C 1 +ATOM 11485 O O . ILE D 2 316 ? -64.606 -10.061 -79.884 1.00 66.61 ? 316 ILE D O 1 +ATOM 11486 C CB . ILE D 2 316 ? -64.923 -12.115 -82.679 1.00 58.35 ? 316 ILE D CB 1 +ATOM 11487 C CG1 . ILE D 2 316 ? -64.991 -13.594 -83.073 1.00 64.48 ? 316 ILE D CG1 1 +ATOM 11488 C CG2 . ILE D 2 316 ? -63.499 -11.613 -82.866 1.00 47.45 ? 316 ILE D CG2 1 +ATOM 11489 C CD1 . ILE D 2 316 ? -63.925 -14.456 -82.423 1.00 63.71 ? 316 ILE D CD1 1 +ATOM 11490 N N . ARG D 2 317 ? -65.975 -9.565 -81.610 1.00 63.25 ? 317 ARG D N 1 +ATOM 11491 C CA . ARG D 2 317 ? -65.763 -8.122 -81.496 1.00 58.89 ? 317 ARG D CA 1 +ATOM 11492 C C . ARG D 2 317 ? -66.293 -7.572 -80.177 1.00 61.60 ? 317 ARG D C 1 +ATOM 11493 O O . ARG D 2 317 ? -65.596 -6.827 -79.477 1.00 59.09 ? 317 ARG D O 1 +ATOM 11494 C CB . ARG D 2 317 ? -66.420 -7.403 -82.673 1.00 50.31 ? 317 ARG D CB 1 +ATOM 11495 C CG . ARG D 2 317 ? -66.242 -5.900 -82.646 1.00 46.30 ? 317 ARG D CG 1 +ATOM 11496 C CD . ARG D 2 317 ? -67.073 -5.227 -83.722 1.00 48.36 ? 317 ARG D CD 1 +ATOM 11497 N NE . ARG D 2 317 ? -68.502 -5.419 -83.510 1.00 53.12 ? 317 ARG D NE 1 +ATOM 11498 C CZ . ARG D 2 317 ? -69.441 -5.055 -84.376 1.00 51.61 ? 317 ARG D CZ 1 +ATOM 11499 N NH1 . ARG D 2 317 ? -69.107 -4.480 -85.524 1.00 47.65 ? 317 ARG D NH1 1 +ATOM 11500 N NH2 . ARG D 2 317 ? -70.718 -5.271 -84.095 1.00 54.14 ? 317 ARG D NH2 1 +ATOM 11501 N N . ASP D 2 318 ? -67.523 -7.923 -79.825 1.00 62.47 ? 318 ASP D N 1 +ATOM 11502 C CA . ASP D 2 318 ? -68.205 -7.335 -78.682 1.00 62.25 ? 318 ASP D CA 1 +ATOM 11503 C C . ASP D 2 318 ? -67.828 -7.989 -77.355 1.00 65.20 ? 318 ASP D C 1 +ATOM 11504 O O . ASP D 2 318 ? -68.459 -7.689 -76.335 1.00 66.23 ? 318 ASP D O 1 +ATOM 11505 C CB . ASP D 2 318 ? -69.718 -7.404 -78.900 1.00 60.50 ? 318 ASP D CB 1 +ATOM 11506 C CG . ASP D 2 318 ? -70.154 -6.691 -80.170 1.00 58.96 ? 318 ASP D CG 1 +ATOM 11507 O OD1 . ASP D 2 318 ? -69.280 -6.158 -80.885 1.00 60.51 ? 318 ASP D OD1 1 +ATOM 11508 O OD2 . ASP D 2 318 ? -71.367 -6.676 -80.464 1.00 60.88 ? 318 ASP D OD2 1 +ATOM 11509 N N . VAL D 2 319 ? -66.835 -8.880 -77.341 1.00 60.75 ? 319 VAL D N 1 +ATOM 11510 C CA . VAL D 2 319 ? -66.432 -9.545 -76.105 1.00 59.60 ? 319 VAL D CA 1 +ATOM 11511 C C . VAL D 2 319 ? -64.917 -9.540 -75.963 1.00 55.91 ? 319 VAL D C 1 +ATOM 11512 O O . VAL D 2 319 ? -64.327 -10.522 -75.499 1.00 57.94 ? 319 VAL D O 1 +ATOM 11513 C CB . VAL D 2 319 ? -66.972 -10.985 -76.037 1.00 59.66 ? 319 VAL D CB 1 +ATOM 11514 C CG1 . VAL D 2 319 ? -68.482 -10.974 -75.838 1.00 63.28 ? 319 VAL D CG1 1 +ATOM 11515 C CG2 . VAL D 2 319 ? -66.591 -11.760 -77.284 1.00 62.21 ? 319 VAL D CG2 1 +ATOM 11516 N N . THR D 2 320 ? -64.275 -8.441 -76.348 1.00 51.62 ? 320 THR D N 1 +ATOM 11517 C CA . THR D 2 320 ? -62.836 -8.307 -76.176 1.00 57.12 ? 320 THR D CA 1 +ATOM 11518 C C . THR D 2 320 ? -62.493 -6.906 -75.702 1.00 63.27 ? 320 THR D C 1 +ATOM 11519 O O . THR D 2 320 ? -62.946 -5.920 -76.292 1.00 68.20 ? 320 THR D O 1 +ATOM 11520 C CB . THR D 2 320 ? -62.089 -8.614 -77.476 1.00 55.16 ? 320 THR D CB 1 +ATOM 11521 O OG1 . THR D 2 320 ? -60.709 -8.255 -77.327 1.00 57.33 ? 320 THR D OG1 1 +ATOM 11522 C CG2 . THR D 2 320 ? -62.691 -7.850 -78.637 1.00 55.38 ? 320 THR D CG2 1 +ATOM 11523 N N . ARG D 2 321 ? -61.702 -6.819 -74.630 1.00 61.99 ? 321 ARG D N 1 +ATOM 11524 C CA . ARG D 2 321 ? -61.151 -5.547 -74.183 1.00 69.21 ? 321 ARG D CA 1 +ATOM 11525 C C . ARG D 2 321 ? -59.737 -5.312 -74.709 1.00 72.85 ? 321 ARG D C 1 +ATOM 11526 O O . ARG D 2 321 ? -58.981 -4.533 -74.116 1.00 74.88 ? 321 ARG D O 1 +ATOM 11527 C CB . ARG D 2 321 ? -61.164 -5.441 -72.655 1.00 79.56 ? 321 ARG D CB 1 +ATOM 11528 C CG . ARG D 2 321 ? -60.723 -6.685 -71.897 1.00 94.20 ? 321 ARG D CG 1 +ATOM 11529 C CD . ARG D 2 321 ? -60.511 -6.371 -70.412 1.00 85.77 ? 321 ARG D CD 1 +ATOM 11530 N NE . ARG D 2 321 ? -61.750 -6.022 -69.721 1.00 95.80 ? 321 ARG D NE 1 +ATOM 11531 C CZ . ARG D 2 321 ? -62.508 -6.891 -69.061 1.00 100.23 ? 321 ARG D CZ 1 +ATOM 11532 N NH1 . ARG D 2 321 ? -62.157 -8.169 -69.000 1.00 88.96 ? 321 ARG D NH1 1 +ATOM 11533 N NH2 . ARG D 2 321 ? -63.618 -6.482 -68.459 1.00 100.85 ? 321 ARG D NH2 1 +ATOM 11534 N N . ASP D 2 322 ? -59.355 -5.992 -75.788 1.00 71.15 ? 322 ASP D N 1 +ATOM 11535 C CA . ASP D 2 322 ? -58.046 -5.804 -76.406 1.00 73.95 ? 322 ASP D CA 1 +ATOM 11536 C C . ASP D 2 322 ? -58.161 -4.633 -77.381 1.00 71.69 ? 322 ASP D C 1 +ATOM 11537 O O . ASP D 2 322 ? -58.869 -4.724 -78.393 1.00 60.94 ? 322 ASP D O 1 +ATOM 11538 C CB . ASP D 2 322 ? -57.590 -7.085 -77.105 1.00 68.49 ? 322 ASP D CB 1 +ATOM 11539 C CG . ASP D 2 322 ? -56.144 -7.015 -77.593 1.00 63.60 ? 322 ASP D CG 1 +ATOM 11540 O OD1 . ASP D 2 322 ? -55.846 -6.186 -78.480 1.00 66.24 ? 322 ASP D OD1 1 +ATOM 11541 O OD2 . ASP D 2 322 ? -55.308 -7.813 -77.112 1.00 55.06 ? 322 ASP D OD2 1 +ATOM 11542 N N . LYS D 2 323 ? -57.480 -3.526 -77.065 1.00 69.64 ? 323 LYS D N 1 +ATOM 11543 C CA . LYS D 2 323 ? -57.586 -2.336 -77.903 1.00 66.12 ? 323 LYS D CA 1 +ATOM 11544 C C . LYS D 2 323 ? -57.007 -2.570 -79.291 1.00 62.52 ? 323 LYS D C 1 +ATOM 11545 O O . LYS D 2 323 ? -57.501 -2.002 -80.270 1.00 64.50 ? 323 LYS D O 1 +ATOM 11546 C CB . LYS D 2 323 ? -56.890 -1.145 -77.239 1.00 69.50 ? 323 LYS D CB 1 +ATOM 11547 C CG . LYS D 2 323 ? -57.387 -0.800 -75.836 1.00 79.53 ? 323 LYS D CG 1 +ATOM 11548 C CD . LYS D 2 323 ? -56.631 0.404 -75.271 1.00 83.72 ? 323 LYS D CD 1 +ATOM 11549 C CE . LYS D 2 323 ? -56.869 1.652 -76.134 1.00 79.33 ? 323 LYS D CE 1 +ATOM 11550 N NZ . LYS D 2 323 ? -56.154 2.873 -75.660 1.00 61.85 ? 323 LYS D NZ 1 +ATOM 11551 N N . LYS D 2 324 ? -55.985 -3.417 -79.401 1.00 63.66 ? 324 LYS D N 1 +ATOM 11552 C CA . LYS D 2 324 ? -55.370 -3.665 -80.700 1.00 61.00 ? 324 LYS D CA 1 +ATOM 11553 C C . LYS D 2 324 ? -56.318 -4.425 -81.618 1.00 56.01 ? 324 LYS D C 1 +ATOM 11554 O O . LYS D 2 324 ? -56.534 -4.030 -82.770 1.00 52.86 ? 324 LYS D O 1 +ATOM 11555 C CB . LYS D 2 324 ? -54.063 -4.438 -80.517 1.00 72.31 ? 324 LYS D CB 1 +ATOM 11556 C CG . LYS D 2 324 ? -53.314 -4.104 -79.232 1.00 80.44 ? 324 LYS D CG 1 +ATOM 11557 C CD . LYS D 2 324 ? -52.218 -5.124 -78.938 1.00 83.70 ? 324 LYS D CD 1 +ATOM 11558 C CE . LYS D 2 324 ? -51.239 -5.242 -80.109 1.00 91.56 ? 324 LYS D CE 1 +ATOM 11559 N NZ . LYS D 2 324 ? -50.657 -3.938 -80.551 1.00 73.22 ? 324 LYS D NZ 1 +ATOM 11560 N N . LEU D 2 325 ? -56.898 -5.518 -81.116 1.00 60.20 ? 325 LEU D N 1 +ATOM 11561 C CA . LEU D 2 325 ? -57.730 -6.388 -81.941 1.00 53.28 ? 325 LEU D CA 1 +ATOM 11562 C C . LEU D 2 325 ? -59.016 -5.691 -82.368 1.00 50.28 ? 325 LEU D C 1 +ATOM 11563 O O . LEU D 2 325 ? -59.492 -5.891 -83.492 1.00 44.00 ? 325 LEU D O 1 +ATOM 11564 C CB . LEU D 2 325 ? -58.025 -7.684 -81.178 1.00 48.42 ? 325 LEU D CB 1 +ATOM 11565 C CG . LEU D 2 325 ? -58.735 -8.875 -81.831 1.00 40.84 ? 325 LEU D CG 1 +ATOM 11566 C CD1 . LEU D 2 325 ? -60.234 -8.799 -81.651 1.00 55.06 ? 325 LEU D CD1 1 +ATOM 11567 C CD2 . LEU D 2 325 ? -58.400 -8.986 -83.303 1.00 51.03 ? 325 LEU D CD2 1 +ATOM 11568 N N . TRP D 2 326 ? -59.605 -4.882 -81.486 1.00 52.42 ? 326 TRP D N 1 +ATOM 11569 C CA . TRP D 2 326 ? -60.900 -4.294 -81.808 1.00 54.35 ? 326 TRP D CA 1 +ATOM 11570 C C . TRP D 2 326 ? -60.786 -3.213 -82.879 1.00 51.81 ? 326 TRP D C 1 +ATOM 11571 O O . TRP D 2 326 ? -61.688 -3.078 -83.714 1.00 49.85 ? 326 TRP D O 1 +ATOM 11572 C CB . TRP D 2 326 ? -61.552 -3.718 -80.552 1.00 56.34 ? 326 TRP D CB 1 +ATOM 11573 C CG . TRP D 2 326 ? -62.943 -3.222 -80.807 1.00 61.85 ? 326 TRP D CG 1 +ATOM 11574 C CD1 . TRP D 2 326 ? -64.104 -3.935 -80.690 1.00 63.37 ? 326 TRP D CD1 1 +ATOM 11575 C CD2 . TRP D 2 326 ? -63.318 -1.919 -81.274 1.00 59.81 ? 326 TRP D CD2 1 +ATOM 11576 N NE1 . TRP D 2 326 ? -65.180 -3.146 -81.028 1.00 61.53 ? 326 TRP D NE1 1 +ATOM 11577 C CE2 . TRP D 2 326 ? -64.723 -1.906 -81.394 1.00 63.02 ? 326 TRP D CE2 1 +ATOM 11578 C CE3 . TRP D 2 326 ? -62.601 -0.761 -81.593 1.00 50.48 ? 326 TRP D CE3 1 +ATOM 11579 C CZ2 . TRP D 2 326 ? -65.425 -0.781 -81.820 1.00 60.66 ? 326 TRP D CZ2 1 +ATOM 11580 C CZ3 . TRP D 2 326 ? -63.296 0.351 -82.015 1.00 55.18 ? 326 TRP D CZ3 1 +ATOM 11581 C CH2 . TRP D 2 326 ? -64.694 0.335 -82.126 1.00 59.92 ? 326 TRP D CH2 1 +ATOM 11582 N N . ARG D 2 327 ? -59.690 -2.451 -82.893 1.00 46.52 ? 327 ARG D N 1 +ATOM 11583 C CA . ARG D 2 327 ? -59.576 -1.334 -83.827 1.00 40.84 ? 327 ARG D CA 1 +ATOM 11584 C C . ARG D 2 327 ? -59.438 -1.767 -85.274 1.00 44.64 ? 327 ARG D C 1 +ATOM 11585 O O . ARG D 2 327 ? -59.284 -0.895 -86.134 1.00 51.46 ? 327 ARG D O 1 +ATOM 11586 C CB . ARG D 2 327 ? -58.387 -0.442 -83.465 1.00 47.38 ? 327 ARG D CB 1 +ATOM 11587 C CG . ARG D 2 327 ? -58.621 0.449 -82.260 1.00 64.25 ? 327 ARG D CG 1 +ATOM 11588 C CD . ARG D 2 327 ? -58.174 1.884 -82.516 1.00 68.34 ? 327 ARG D CD 1 +ATOM 11589 N NE . ARG D 2 327 ? -57.720 2.529 -81.287 1.00 83.25 ? 327 ARG D NE 1 +ATOM 11590 C CZ . ARG D 2 327 ? -56.458 2.535 -80.866 1.00 90.51 ? 327 ARG D CZ 1 +ATOM 11591 N NH1 . ARG D 2 327 ? -55.516 1.935 -81.585 1.00 80.28 ? 327 ARG D NH1 1 +ATOM 11592 N NH2 . ARG D 2 327 ? -56.137 3.143 -79.729 1.00 94.55 ? 327 ARG D NH2 1 +ATOM 11593 N N . THR D 2 328 ? -59.478 -3.062 -85.579 1.00 45.10 ? 328 THR D N 1 +ATOM 11594 C CA . THR D 2 328 ? -59.374 -3.527 -86.955 1.00 41.87 ? 328 THR D CA 1 +ATOM 11595 C C . THR D 2 328 ? -60.682 -4.088 -87.484 1.00 41.92 ? 328 THR D C 1 +ATOM 11596 O O . THR D 2 328 ? -60.689 -4.711 -88.549 1.00 46.90 ? 328 THR D O 1 +ATOM 11597 C CB . THR D 2 328 ? -58.288 -4.591 -87.090 1.00 39.88 ? 328 THR D CB 1 +ATOM 11598 O OG1 . THR D 2 328 ? -58.741 -5.806 -86.488 1.00 40.80 ? 328 THR D OG1 1 +ATOM 11599 C CG2 . THR D 2 328 ? -57.012 -4.137 -86.401 1.00 45.26 ? 328 THR D CG2 1 +ATOM 11600 N N . PHE D 2 329 ? -61.783 -3.912 -86.763 1.00 44.41 ? 329 PHE D N 1 +ATOM 11601 C CA . PHE D 2 329 ? -63.073 -4.443 -87.196 1.00 49.95 ? 329 PHE D CA 1 +ATOM 11602 C C . PHE D 2 329 ? -63.760 -3.424 -88.096 1.00 52.32 ? 329 PHE D C 1 +ATOM 11603 O O . PHE D 2 329 ? -64.379 -2.472 -87.619 1.00 62.00 ? 329 PHE D O 1 +ATOM 11604 C CB . PHE D 2 329 ? -63.937 -4.804 -85.995 1.00 51.04 ? 329 PHE D CB 1 +ATOM 11605 C CG . PHE D 2 329 ? -63.963 -6.273 -85.697 1.00 44.20 ? 329 PHE D CG 1 +ATOM 11606 C CD1 . PHE D 2 329 ? -63.004 -6.843 -84.878 1.00 41.17 ? 329 PHE D CD1 1 +ATOM 11607 C CD2 . PHE D 2 329 ? -64.949 -7.082 -86.235 1.00 39.23 ? 329 PHE D CD2 1 +ATOM 11608 C CE1 . PHE D 2 329 ? -63.028 -8.192 -84.604 1.00 42.69 ? 329 PHE D CE1 1 +ATOM 11609 C CE2 . PHE D 2 329 ? -64.980 -8.429 -85.965 1.00 41.52 ? 329 PHE D CE2 1 +ATOM 11610 C CZ . PHE D 2 329 ? -64.017 -8.987 -85.150 1.00 45.41 ? 329 PHE D CZ 1 +ATOM 11611 N N . PHE D 2 330 ? -63.638 -3.623 -89.405 1.00 46.09 ? 330 PHE D N 1 +ATOM 11612 C CA . PHE D 2 330 ? -64.269 -2.780 -90.407 1.00 48.57 ? 330 PHE D CA 1 +ATOM 11613 C C . PHE D 2 330 ? -65.291 -3.579 -91.206 1.00 52.99 ? 330 PHE D C 1 +ATOM 11614 O O . PHE D 2 330 ? -65.271 -4.812 -91.227 1.00 52.58 ? 330 PHE D O 1 +ATOM 11615 C CB . PHE D 2 330 ? -63.232 -2.194 -91.366 1.00 54.55 ? 330 PHE D CB 1 +ATOM 11616 C CG . PHE D 2 330 ? -62.561 -3.228 -92.233 1.00 63.69 ? 330 PHE D CG 1 +ATOM 11617 C CD1 . PHE D 2 330 ? -61.453 -3.926 -91.773 1.00 58.08 ? 330 PHE D CD1 1 +ATOM 11618 C CD2 . PHE D 2 330 ? -63.052 -3.517 -93.501 1.00 60.27 ? 330 PHE D CD2 1 +ATOM 11619 C CE1 . PHE D 2 330 ? -60.840 -4.882 -92.567 1.00 53.60 ? 330 PHE D CE1 1 +ATOM 11620 C CE2 . PHE D 2 330 ? -62.447 -4.473 -94.295 1.00 54.95 ? 330 PHE D CE2 1 +ATOM 11621 C CZ . PHE D 2 330 ? -61.338 -5.152 -93.830 1.00 53.59 ? 330 PHE D CZ 1 +ATOM 11622 N N . VAL D 2 331 ? -66.168 -2.859 -91.899 1.00 55.23 ? 331 VAL D N 1 +ATOM 11623 C CA . VAL D 2 331 ? -67.155 -3.461 -92.787 1.00 54.00 ? 331 VAL D CA 1 +ATOM 11624 C C . VAL D 2 331 ? -66.722 -3.200 -94.224 1.00 61.18 ? 331 VAL D C 1 +ATOM 11625 O O . VAL D 2 331 ? -66.375 -2.066 -94.580 1.00 61.99 ? 331 VAL D O 1 +ATOM 11626 C CB . VAL D 2 331 ? -68.567 -2.916 -92.521 1.00 54.60 ? 331 VAL D CB 1 +ATOM 11627 C CG1 . VAL D 2 331 ? -69.600 -3.726 -93.298 1.00 51.10 ? 331 VAL D CG1 1 +ATOM 11628 C CG2 . VAL D 2 331 ? -68.862 -2.926 -91.033 1.00 57.18 ? 331 VAL D CG2 1 +ATOM 11629 N N . SER D 2 332 ? -66.743 -4.245 -95.040 1.00 60.55 ? 332 SER D N 1 +ATOM 11630 C CA . SER D 2 332 ? -66.188 -4.229 -96.386 1.00 52.55 ? 332 SER D CA 1 +ATOM 11631 C C . SER D 2 332 ? -67.205 -3.697 -97.381 1.00 52.51 ? 332 SER D C 1 +ATOM 11632 O O . SER D 2 332 ? -68.391 -3.570 -97.074 1.00 57.00 ? 332 SER D O 1 +ATOM 11633 C CB . SER D 2 332 ? -65.772 -5.639 -96.778 1.00 51.25 ? 332 SER D CB 1 +ATOM 11634 O OG . SER D 2 332 ? -66.918 -6.420 -97.061 1.00 52.32 ? 332 SER D OG 1 +ATOM 11635 N N . PRO D 2 333 ? -66.768 -3.380 -98.606 1.00 55.12 ? 333 PRO D N 1 +ATOM 11636 C CA . PRO D 2 333 ? -67.726 -2.958 -99.643 1.00 55.28 ? 333 PRO D CA 1 +ATOM 11637 C C . PRO D 2 333 ? -68.798 -3.986 -99.948 1.00 49.16 ? 333 PRO D C 1 +ATOM 11638 O O . PRO D 2 333 ? -69.853 -3.617 -100.481 1.00 49.80 ? 333 PRO D O 1 +ATOM 11639 C CB . PRO D 2 333 ? -66.831 -2.709 -100.863 1.00 54.80 ? 333 PRO D CB 1 +ATOM 11640 C CG . PRO D 2 333 ? -65.525 -2.334 -100.282 1.00 56.58 ? 333 PRO D CG 1 +ATOM 11641 C CD . PRO D 2 333 ? -65.375 -3.169 -99.040 1.00 55.45 ? 333 PRO D CD 1 +ATOM 11642 N N . ALA D 2 334 ? -68.563 -5.261 -99.663 1.00 48.04 ? 334 ALA D N 1 +ATOM 11643 C CA . ALA D 2 334 ? -69.618 -6.254 -99.794 1.00 58.22 ? 334 ALA D CA 1 +ATOM 11644 C C . ALA D 2 334 ? -70.542 -6.289 -98.586 1.00 63.00 ? 334 ALA D C 1 +ATOM 11645 O O . ALA D 2 334 ? -71.311 -7.246 -98.443 1.00 70.37 ? 334 ALA D O 1 +ATOM 11646 C CB . ALA D 2 334 ? -69.017 -7.643 -100.021 1.00 60.85 ? 334 ALA D CB 1 +ATOM 11647 N N . ASN D 2 335 ? -70.482 -5.270 -97.724 1.00 64.28 ? 335 ASN D N 1 +ATOM 11648 C CA . ASN D 2 335 ? -71.310 -5.180 -96.520 1.00 70.23 ? 335 ASN D CA 1 +ATOM 11649 C C . ASN D 2 335 ? -71.089 -6.375 -95.592 1.00 69.30 ? 335 ASN D C 1 +ATOM 11650 O O . ASN D 2 335 ? -71.979 -6.767 -94.832 1.00 68.62 ? 335 ASN D O 1 +ATOM 11651 C CB . ASN D 2 335 ? -72.792 -5.027 -96.874 1.00 72.66 ? 335 ASN D CB 1 +ATOM 11652 C CG . ASN D 2 335 ? -73.558 -4.240 -95.831 1.00 76.37 ? 335 ASN D CG 1 +ATOM 11653 O OD1 . ASN D 2 335 ? -73.595 -3.011 -95.874 1.00 68.78 ? 335 ASN D OD1 1 +ATOM 11654 N ND2 . ASN D 2 335 ? -74.181 -4.945 -94.890 1.00 86.53 ? 335 ASN D ND2 1 +ATOM 11655 N N . ASN D 2 336 ? -69.902 -6.970 -95.660 1.00 63.87 ? 336 ASN D N 1 +ATOM 11656 C CA . ASN D 2 336 ? -69.488 -8.047 -94.775 1.00 57.28 ? 336 ASN D CA 1 +ATOM 11657 C C . ASN D 2 336 ? -68.575 -7.511 -93.679 1.00 63.07 ? 336 ASN D C 1 +ATOM 11658 O O . ASN D 2 336 ? -67.890 -6.498 -93.851 1.00 60.47 ? 336 ASN D O 1 +ATOM 11659 C CB . ASN D 2 336 ? -68.772 -9.143 -95.558 1.00 51.78 ? 336 ASN D CB 1 +ATOM 11660 C CG . ASN D 2 336 ? -69.630 -9.715 -96.650 1.00 54.01 ? 336 ASN D CG 1 +ATOM 11661 O OD1 . ASN D 2 336 ? -70.855 -9.644 -96.579 1.00 56.30 ? 336 ASN D OD1 1 +ATOM 11662 N ND2 . ASN D 2 336 ? -69.000 -10.279 -97.675 1.00 53.33 ? 336 ASN D ND2 1 +ATOM 11663 N N . ILE D 2 337 ? -68.583 -8.192 -92.538 1.00 64.48 ? 337 ILE D N 1 +ATOM 11664 C CA . ILE D 2 337 ? -67.750 -7.802 -91.408 1.00 58.01 ? 337 ILE D CA 1 +ATOM 11665 C C . ILE D 2 337 ? -66.397 -8.483 -91.533 1.00 50.77 ? 337 ILE D C 1 +ATOM 11666 O O . ILE D 2 337 ? -66.308 -9.682 -91.820 1.00 47.78 ? 337 ILE D O 1 +ATOM 11667 C CB . ILE D 2 337 ? -68.438 -8.143 -90.075 1.00 49.08 ? 337 ILE D CB 1 +ATOM 11668 C CG1 . ILE D 2 337 ? -69.870 -7.605 -90.082 1.00 49.81 ? 337 ILE D CG1 1 +ATOM 11669 C CG2 . ILE D 2 337 ? -67.655 -7.557 -88.914 1.00 51.03 ? 337 ILE D CG2 1 +ATOM 11670 C CD1 . ILE D 2 337 ? -70.630 -7.841 -88.797 1.00 61.24 ? 337 ILE D CD1 1 +ATOM 11671 N N . CYS D 2 338 ? -65.336 -7.711 -91.305 1.00 48.69 ? 338 CYS D N 1 +ATOM 11672 C CA . CYS D 2 338 ? -63.977 -8.189 -91.482 1.00 48.82 ? 338 CYS D CA 1 +ATOM 11673 C C . CYS D 2 338 ? -63.119 -7.748 -90.303 1.00 48.58 ? 338 CYS D C 1 +ATOM 11674 O O . CYS D 2 338 ? -63.411 -6.756 -89.632 1.00 50.63 ? 338 CYS D O 1 +ATOM 11675 C CB . CYS D 2 338 ? -63.371 -7.656 -92.787 1.00 53.44 ? 338 CYS D CB 1 +ATOM 11676 S SG . CYS D 2 338 ? -64.344 -7.954 -94.278 1.00 52.41 ? 338 CYS D SG 1 +ATOM 11677 N N . PHE D 2 339 ? -62.046 -8.499 -90.063 1.00 45.25 ? 339 PHE D N 1 +ATOM 11678 C CA . PHE D 2 339 ? -61.027 -8.116 -89.094 1.00 44.07 ? 339 PHE D CA 1 +ATOM 11679 C C . PHE D 2 339 ? -59.732 -8.816 -89.467 1.00 42.74 ? 339 PHE D C 1 +ATOM 11680 O O . PHE D 2 339 ? -59.749 -9.878 -90.092 1.00 44.39 ? 339 PHE D O 1 +ATOM 11681 C CB . PHE D 2 339 ? -61.429 -8.461 -87.655 1.00 47.15 ? 339 PHE D CB 1 +ATOM 11682 C CG . PHE D 2 339 ? -61.269 -9.917 -87.305 1.00 44.08 ? 339 PHE D CG 1 +ATOM 11683 C CD1 . PHE D 2 339 ? -62.217 -10.847 -87.699 1.00 38.18 ? 339 PHE D CD1 1 +ATOM 11684 C CD2 . PHE D 2 339 ? -60.169 -10.353 -86.580 1.00 42.34 ? 339 PHE D CD2 1 +ATOM 11685 C CE1 . PHE D 2 339 ? -62.075 -12.177 -87.377 1.00 38.00 ? 339 PHE D CE1 1 +ATOM 11686 C CE2 . PHE D 2 339 ? -60.020 -11.687 -86.258 1.00 38.00 ? 339 PHE D CE2 1 +ATOM 11687 C CZ . PHE D 2 339 ? -60.975 -12.600 -86.659 1.00 38.00 ? 339 PHE D CZ 1 +ATOM 11688 N N . TYR D 2 340 ? -58.608 -8.201 -89.104 1.00 41.01 ? 340 TYR D N 1 +ATOM 11689 C CA . TYR D 2 340 ? -57.322 -8.796 -89.447 1.00 43.10 ? 340 TYR D CA 1 +ATOM 11690 C C . TYR D 2 340 ? -56.402 -8.910 -88.241 1.00 40.50 ? 340 TYR D C 1 +ATOM 11691 O O . TYR D 2 340 ? -55.544 -9.800 -88.196 1.00 47.91 ? 340 TYR D O 1 +ATOM 11692 C CB . TYR D 2 340 ? -56.643 -8.013 -90.580 1.00 47.65 ? 340 TYR D CB 1 +ATOM 11693 C CG . TYR D 2 340 ? -56.622 -6.500 -90.448 1.00 49.42 ? 340 TYR D CG 1 +ATOM 11694 C CD1 . TYR D 2 340 ? -57.722 -5.732 -90.821 1.00 48.49 ? 340 TYR D CD1 1 +ATOM 11695 C CD2 . TYR D 2 340 ? -55.486 -5.837 -89.998 1.00 50.37 ? 340 TYR D CD2 1 +ATOM 11696 C CE1 . TYR D 2 340 ? -57.700 -4.350 -90.721 1.00 45.64 ? 340 TYR D CE1 1 +ATOM 11697 C CE2 . TYR D 2 340 ? -55.454 -4.456 -89.896 1.00 47.73 ? 340 TYR D CE2 1 +ATOM 11698 C CZ . TYR D 2 340 ? -56.563 -3.719 -90.259 1.00 49.53 ? 340 TYR D CZ 1 +ATOM 11699 O OH . TYR D 2 340 ? -56.539 -2.347 -90.162 1.00 56.75 ? 340 TYR D OH 1 +ATOM 11700 N N . GLY D 2 341 ? -56.566 -8.035 -87.262 1.00 41.36 ? 341 GLY D N 1 +ATOM 11701 C CA . GLY D 2 341 ? -55.726 -8.096 -86.086 1.00 51.09 ? 341 GLY D CA 1 +ATOM 11702 C C . GLY D 2 341 ? -54.411 -7.358 -86.254 1.00 51.32 ? 341 GLY D C 1 +ATOM 11703 O O . GLY D 2 341 ? -54.260 -6.444 -87.070 1.00 52.46 ? 341 GLY D O 1 +ATOM 11704 N N . GLU D 2 342 ? -53.442 -7.764 -85.444 1.00 51.03 ? 342 GLU D N 1 +ATOM 11705 C CA . GLU D 2 342 ? -52.143 -7.119 -85.457 1.00 61.35 ? 342 GLU D CA 1 +ATOM 11706 C C . GLU D 2 342 ? -51.066 -8.139 -85.105 1.00 58.49 ? 342 GLU D C 1 +ATOM 11707 O O . GLU D 2 342 ? -50.374 -8.034 -84.097 1.00 60.83 ? 342 GLU D O 1 +ATOM 11708 C CB . GLU D 2 342 ? -52.110 -5.927 -84.503 1.00 71.20 ? 342 GLU D CB 1 +ATOM 11709 C CG . GLU D 2 342 ? -51.508 -4.675 -85.111 1.00 75.53 ? 342 GLU D CG 1 +ATOM 11710 C CD . GLU D 2 342 ? -51.708 -3.452 -84.239 1.00 95.00 ? 342 GLU D CD 1 +ATOM 11711 O OE1 . GLU D 2 342 ? -51.800 -3.614 -83.003 1.00 89.44 ? 342 GLU D OE1 1 +ATOM 11712 O OE2 . GLU D 2 342 ? -51.760 -2.330 -84.787 1.00 115.45 ? 342 GLU D OE2 1 +ATOM 11713 N N . CYS D 2 343 ? -50.934 -9.174 -85.930 1.00 56.45 ? 343 CYS D N 1 +ATOM 11714 C CA . CYS D 2 343 ? -49.808 -10.085 -85.781 1.00 55.82 ? 343 CYS D CA 1 +ATOM 11715 C C . CYS D 2 343 ? -48.658 -9.622 -86.666 1.00 57.31 ? 343 CYS D C 1 +ATOM 11716 O O . CYS D 2 343 ? -48.285 -8.446 -86.631 1.00 67.91 ? 343 CYS D O 1 +ATOM 11717 C CB . CYS D 2 343 ? -50.219 -11.515 -86.114 1.00 58.22 ? 343 CYS D CB 1 +ATOM 11718 S SG . CYS D 2 343 ? -50.542 -11.801 -87.858 1.00 72.47 ? 343 CYS D SG 1 +ATOM 11719 N N . SER D 2 344 ? -48.108 -10.515 -87.488 1.00 50.50 ? 344 SER D N 1 +ATOM 11720 C CA . SER D 2 344 ? -46.947 -10.144 -88.291 1.00 50.56 ? 344 SER D CA 1 +ATOM 11721 C C . SER D 2 344 ? -47.045 -10.681 -89.716 1.00 53.44 ? 344 SER D C 1 +ATOM 11722 O O . SER D 2 344 ? -46.543 -10.051 -90.653 1.00 49.46 ? 344 SER D O 1 +ATOM 11723 C CB . SER D 2 344 ? -45.657 -10.616 -87.610 1.00 53.46 ? 344 SER D CB 1 +ATOM 11724 O OG . SER D 2 344 ? -45.554 -12.027 -87.606 1.00 64.85 ? 344 SER D OG 1 +ATOM 11725 N N . TYR D 2 345 ? -47.642 -11.859 -89.882 1.00 57.40 ? 345 TYR D N 1 +ATOM 11726 C CA . TYR D 2 345 ? -47.862 -12.482 -91.185 1.00 48.97 ? 345 TYR D CA 1 +ATOM 11727 C C . TYR D 2 345 ? -49.339 -12.405 -91.538 1.00 46.30 ? 345 TYR D C 1 +ATOM 11728 O O . TYR D 2 345 ? -50.178 -12.925 -90.798 1.00 55.00 ? 345 TYR D O 1 +ATOM 11729 C CB . TYR D 2 345 ? -47.410 -13.942 -91.190 1.00 57.51 ? 345 TYR D CB 1 +ATOM 11730 C CG . TYR D 2 345 ? -46.039 -14.165 -91.774 1.00 61.51 ? 345 TYR D CG 1 +ATOM 11731 C CD1 . TYR D 2 345 ? -45.158 -13.108 -91.945 1.00 61.18 ? 345 TYR D CD1 1 +ATOM 11732 C CD2 . TYR D 2 345 ? -45.630 -15.431 -92.166 1.00 61.18 ? 345 TYR D CD2 1 +ATOM 11733 C CE1 . TYR D 2 345 ? -43.905 -13.306 -92.477 1.00 58.05 ? 345 TYR D CE1 1 +ATOM 11734 C CE2 . TYR D 2 345 ? -44.378 -15.637 -92.703 1.00 62.76 ? 345 TYR D CE2 1 +ATOM 11735 C CZ . TYR D 2 345 ? -43.518 -14.568 -92.857 1.00 60.59 ? 345 TYR D CZ 1 +ATOM 11736 O OH . TYR D 2 345 ? -42.263 -14.748 -93.390 1.00 64.27 ? 345 TYR D OH 1 +ATOM 11737 N N . TYR D 2 346 ? -49.656 -11.748 -92.651 1.00 46.25 ? 346 TYR D N 1 +ATOM 11738 C CA . TYR D 2 346 ? -51.026 -11.710 -93.168 1.00 50.31 ? 346 TYR D CA 1 +ATOM 11739 C C . TYR D 2 346 ? -51.984 -11.125 -92.132 1.00 51.61 ? 346 TYR D C 1 +ATOM 11740 O O . TYR D 2 346 ? -53.082 -11.640 -91.908 1.00 46.22 ? 346 TYR D O 1 +ATOM 11741 C CB . TYR D 2 346 ? -51.497 -13.096 -93.628 1.00 48.55 ? 346 TYR D CB 1 +ATOM 11742 C CG . TYR D 2 346 ? -50.474 -13.848 -94.454 1.00 52.70 ? 346 TYR D CG 1 +ATOM 11743 C CD1 . TYR D 2 346 ? -49.798 -13.228 -95.497 1.00 54.69 ? 346 TYR D CD1 1 +ATOM 11744 C CD2 . TYR D 2 346 ? -50.185 -15.182 -94.192 1.00 54.93 ? 346 TYR D CD2 1 +ATOM 11745 C CE1 . TYR D 2 346 ? -48.855 -13.913 -96.249 1.00 57.37 ? 346 TYR D CE1 1 +ATOM 11746 C CE2 . TYR D 2 346 ? -49.247 -15.875 -94.940 1.00 54.04 ? 346 TYR D CE2 1 +ATOM 11747 C CZ . TYR D 2 346 ? -48.586 -15.236 -95.966 1.00 56.71 ? 346 TYR D CZ 1 +ATOM 11748 O OH . TYR D 2 346 ? -47.653 -15.923 -96.710 1.00 58.23 ? 346 TYR D OH 1 +ATOM 11749 N N . CYS D 2 347 ? -51.530 -10.083 -91.448 1.00 52.63 ? 347 CYS D N 1 +ATOM 11750 C CA . CYS D 2 347 ? -52.357 -9.296 -90.539 1.00 53.13 ? 347 CYS D CA 1 +ATOM 11751 C C . CYS D 2 347 ? -52.432 -7.877 -91.094 1.00 53.60 ? 347 CYS D C 1 +ATOM 11752 O O . CYS D 2 347 ? -51.835 -6.945 -90.547 1.00 59.48 ? 347 CYS D O 1 +ATOM 11753 C CB . CYS D 2 347 ? -51.806 -9.330 -89.107 1.00 56.88 ? 347 CYS D CB 1 +ATOM 11754 S SG . CYS D 2 347 ? -52.287 -10.824 -88.219 1.00 57.97 ? 347 CYS D SG 1 +ATOM 11755 N N . SER D 2 348 ? -53.151 -7.727 -92.205 1.00 52.55 ? 348 SER D N 1 +ATOM 11756 C CA . SER D 2 348 ? -53.366 -6.432 -92.835 1.00 56.98 ? 348 SER D CA 1 +ATOM 11757 C C . SER D 2 348 ? -54.726 -6.448 -93.524 1.00 49.77 ? 348 SER D C 1 +ATOM 11758 O O . SER D 2 348 ? -55.401 -7.481 -93.586 1.00 47.50 ? 348 SER D O 1 +ATOM 11759 C CB . SER D 2 348 ? -52.232 -6.098 -93.817 1.00 60.75 ? 348 SER D CB 1 +ATOM 11760 O OG . SER D 2 348 ? -51.945 -7.183 -94.686 1.00 52.38 ? 348 SER D OG 1 +ATOM 11761 N N . THR D 2 349 ? -55.122 -5.285 -94.050 1.00 44.34 ? 349 THR D N 1 +ATOM 11762 C CA . THR D 2 349 ? -56.434 -5.159 -94.680 1.00 41.66 ? 349 THR D CA 1 +ATOM 11763 C C . THR D 2 349 ? -56.587 -6.138 -95.833 1.00 42.95 ? 349 THR D C 1 +ATOM 11764 O O . THR D 2 349 ? -57.667 -6.702 -96.044 1.00 38.00 ? 349 THR D O 1 +ATOM 11765 C CB . THR D 2 349 ? -56.647 -3.732 -95.181 1.00 45.74 ? 349 THR D CB 1 +ATOM 11766 O OG1 . THR D 2 349 ? -56.362 -2.799 -94.132 1.00 54.38 ? 349 THR D OG1 1 +ATOM 11767 C CG2 . THR D 2 349 ? -58.084 -3.545 -95.645 1.00 42.96 ? 349 THR D CG2 1 +ATOM 11768 N N . GLU D 2 350 ? -55.516 -6.344 -96.596 1.00 50.08 ? 350 GLU D N 1 +ATOM 11769 C CA . GLU D 2 350 ? -55.559 -7.183 -97.783 1.00 45.83 ? 350 GLU D CA 1 +ATOM 11770 C C . GLU D 2 350 ? -55.544 -8.671 -97.457 1.00 46.11 ? 350 GLU D C 1 +ATOM 11771 O O . GLU D 2 350 ? -55.560 -9.493 -98.379 1.00 50.06 ? 350 GLU D O 1 +ATOM 11772 C CB . GLU D 2 350 ? -54.401 -6.826 -98.724 1.00 39.84 ? 350 GLU D CB 1 +ATOM 11773 C CG . GLU D 2 350 ? -53.165 -6.231 -98.045 1.00 44.98 ? 350 GLU D CG 1 +ATOM 11774 C CD . GLU D 2 350 ? -53.218 -4.713 -97.882 1.00 45.06 ? 350 GLU D CD 1 +ATOM 11775 O OE1 . GLU D 2 350 ? -54.033 -4.221 -97.079 1.00 48.21 ? 350 GLU D OE1 1 +ATOM 11776 O OE2 . GLU D 2 350 ? -52.433 -4.009 -98.550 1.00 43.80 ? 350 GLU D OE2 1 +ATOM 11777 N N . HIS D 2 351 ? -55.520 -9.042 -96.177 1.00 39.22 ? 351 HIS D N 1 +ATOM 11778 C CA . HIS D 2 351 ? -55.744 -10.427 -95.782 1.00 45.63 ? 351 HIS D CA 1 +ATOM 11779 C C . HIS D 2 351 ? -56.867 -10.527 -94.763 1.00 44.88 ? 351 HIS D C 1 +ATOM 11780 O O . HIS D 2 351 ? -56.937 -11.510 -94.016 1.00 45.55 ? 351 HIS D O 1 +ATOM 11781 C CB . HIS D 2 351 ? -54.473 -11.064 -95.220 1.00 52.55 ? 351 HIS D CB 1 +ATOM 11782 C CG . HIS D 2 351 ? -53.505 -11.514 -96.268 1.00 51.68 ? 351 HIS D CG 1 +ATOM 11783 N ND1 . HIS D 2 351 ? -52.415 -10.762 -96.646 1.00 51.20 ? 351 HIS D ND1 1 +ATOM 11784 C CD2 . HIS D 2 351 ? -53.457 -12.646 -97.008 1.00 47.22 ? 351 HIS D CD2 1 +ATOM 11785 C CE1 . HIS D 2 351 ? -51.740 -11.407 -97.581 1.00 48.58 ? 351 HIS D CE1 1 +ATOM 11786 N NE2 . HIS D 2 351 ? -52.352 -12.553 -97.818 1.00 47.76 ? 351 HIS D NE2 1 +ATOM 11787 N N . ALA D 2 352 ? -57.754 -9.536 -94.736 1.00 43.99 ? 352 ALA D N 1 +ATOM 11788 C CA . ALA D 2 352 ? -58.794 -9.485 -93.721 1.00 47.77 ? 352 ALA D CA 1 +ATOM 11789 C C . ALA D 2 352 ? -59.685 -10.713 -93.795 1.00 46.35 ? 352 ALA D C 1 +ATOM 11790 O O . ALA D 2 352 ? -60.032 -11.188 -94.879 1.00 48.36 ? 352 ALA D O 1 +ATOM 11791 C CB . ALA D 2 352 ? -59.636 -8.221 -93.883 1.00 53.56 ? 352 ALA D CB 1 +ATOM 11792 N N . LEU D 2 353 ? -60.044 -11.227 -92.625 1.00 43.97 ? 353 LEU D N 1 +ATOM 11793 C CA . LEU D 2 353 ? -60.942 -12.366 -92.515 1.00 49.34 ? 353 LEU D CA 1 +ATOM 11794 C C . LEU D 2 353 ? -62.376 -11.861 -92.417 1.00 48.60 ? 353 LEU D C 1 +ATOM 11795 O O . LEU D 2 353 ? -62.721 -11.138 -91.475 1.00 45.37 ? 353 LEU D O 1 +ATOM 11796 C CB . LEU D 2 353 ? -60.569 -13.208 -91.298 1.00 52.06 ? 353 LEU D CB 1 +ATOM 11797 C CG . LEU D 2 353 ? -59.105 -13.656 -91.303 1.00 52.09 ? 353 LEU D CG 1 +ATOM 11798 C CD1 . LEU D 2 353 ? -58.746 -14.384 -90.015 1.00 45.28 ? 353 LEU D CD1 1 +ATOM 11799 C CD2 . LEU D 2 353 ? -58.824 -14.518 -92.528 1.00 61.68 ? 353 LEU D CD2 1 +ATOM 11800 N N . CYS D 2 354 ? -63.212 -12.254 -93.376 1.00 47.95 ? 354 CYS D N 1 +ATOM 11801 C CA . CYS D 2 354 ? -64.588 -11.788 -93.460 1.00 50.81 ? 354 CYS D CA 1 +ATOM 11802 C C . CYS D 2 354 ? -65.546 -12.969 -93.484 1.00 49.09 ? 354 CYS D C 1 +ATOM 11803 O O . CYS D 2 354 ? -65.230 -14.026 -94.037 1.00 51.10 ? 354 CYS D O 1 +ATOM 11804 C CB . CYS D 2 354 ? -64.819 -10.929 -94.710 1.00 50.27 ? 354 CYS D CB 1 +ATOM 11805 S SG . CYS D 2 354 ? -63.565 -9.674 -95.032 1.00 55.50 ? 354 CYS D SG 1 +ATOM 11806 N N . GLY D 2 355 ? -66.705 -12.789 -92.852 1.00 45.94 ? 355 GLY D N 1 +ATOM 11807 C CA . GLY D 2 355 ? -67.812 -13.704 -92.996 1.00 47.67 ? 355 GLY D CA 1 +ATOM 11808 C C . GLY D 2 355 ? -68.812 -13.204 -94.027 1.00 58.26 ? 355 GLY D C 1 +ATOM 11809 O O . GLY D 2 355 ? -68.660 -12.142 -94.624 1.00 64.58 ? 355 GLY D O 1 +ATOM 11810 N N . LYS D 2 356 ? -69.862 -13.998 -94.225 1.00 62.15 ? 356 LYS D N 1 +ATOM 11811 C CA . LYS D 2 356 ? -70.950 -13.639 -95.133 1.00 60.55 ? 356 LYS D CA 1 +ATOM 11812 C C . LYS D 2 356 ? -72.272 -13.809 -94.399 1.00 57.48 ? 356 LYS D C 1 +ATOM 11813 O O . LYS D 2 356 ? -72.894 -14.878 -94.445 1.00 57.50 ? 356 LYS D O 1 +ATOM 11814 C CB . LYS D 2 356 ? -70.911 -14.467 -96.416 1.00 64.75 ? 356 LYS D CB 1 +ATOM 11815 C CG . LYS D 2 356 ? -71.893 -13.993 -97.490 1.00 70.19 ? 356 LYS D CG 1 +ATOM 11816 C CD . LYS D 2 356 ? -71.775 -12.493 -97.736 1.00 69.22 ? 356 LYS D CD 1 +ATOM 11817 C CE . LYS D 2 356 ? -72.677 -12.033 -98.877 1.00 65.43 ? 356 LYS D CE 1 +ATOM 11818 N NZ . LYS D 2 356 ? -71.907 -11.339 -99.955 1.00 59.03 ? 356 LYS D NZ 1 +ATOM 11819 N N . PRO D 2 357 ? -72.735 -12.765 -93.702 1.00 59.07 ? 357 PRO D N 1 +ATOM 11820 C CA . PRO D 2 357 ? -71.959 -11.527 -93.561 1.00 59.88 ? 357 PRO D CA 1 +ATOM 11821 C C . PRO D 2 357 ? -71.171 -11.401 -92.250 1.00 56.79 ? 357 PRO D C 1 +ATOM 11822 O O . PRO D 2 357 ? -70.368 -10.475 -92.122 1.00 49.31 ? 357 PRO D O 1 +ATOM 11823 C CB . PRO D 2 357 ? -73.040 -10.450 -93.646 1.00 62.27 ? 357 PRO D CB 1 +ATOM 11824 C CG . PRO D 2 357 ? -74.247 -11.100 -93.024 1.00 63.22 ? 357 PRO D CG 1 +ATOM 11825 C CD . PRO D 2 357 ? -74.150 -12.580 -93.331 1.00 57.97 ? 357 PRO D CD 1 +ATOM 11826 N N . ASP D 2 358 ? -71.370 -12.327 -91.306 1.00 61.84 ? 358 ASP D N 1 +ATOM 11827 C CA . ASP D 2 358 ? -70.778 -12.174 -89.980 1.00 60.96 ? 358 ASP D CA 1 +ATOM 11828 C C . ASP D 2 358 ? -70.551 -13.529 -89.312 1.00 62.57 ? 358 ASP D C 1 +ATOM 11829 O O . ASP D 2 358 ? -70.709 -13.669 -88.095 1.00 61.87 ? 358 ASP D O 1 +ATOM 11830 C CB . ASP D 2 358 ? -71.646 -11.280 -89.090 1.00 57.29 ? 358 ASP D CB 1 +ATOM 11831 C CG . ASP D 2 358 ? -73.047 -11.833 -88.892 1.00 57.56 ? 358 ASP D CG 1 +ATOM 11832 O OD1 . ASP D 2 358 ? -73.559 -12.517 -89.803 1.00 58.43 ? 358 ASP D OD1 1 +ATOM 11833 O OD2 . ASP D 2 358 ? -73.648 -11.559 -87.832 1.00 65.99 ? 358 ASP D OD2 1 +ATOM 11834 N N . GLN D 2 359 ? -70.114 -14.522 -90.079 1.00 61.50 ? 359 GLN D N 1 +ATOM 11835 C CA . GLN D 2 359 ? -69.742 -15.812 -89.519 1.00 60.68 ? 359 GLN D CA 1 +ATOM 11836 C C . GLN D 2 359 ? -68.446 -16.251 -90.168 1.00 62.87 ? 359 GLN D C 1 +ATOM 11837 O O . GLN D 2 359 ? -68.334 -16.237 -91.397 1.00 73.46 ? 359 GLN D O 1 +ATOM 11838 C CB . GLN D 2 359 ? -70.829 -16.863 -89.740 1.00 58.40 ? 359 GLN D CB 1 +ATOM 11839 C CG . GLN D 2 359 ? -72.117 -16.548 -89.030 1.00 52.30 ? 359 GLN D CG 1 +ATOM 11840 C CD . GLN D 2 359 ? -72.963 -17.776 -88.825 1.00 50.61 ? 359 GLN D CD 1 +ATOM 11841 O OE1 . GLN D 2 359 ? -72.731 -18.561 -87.904 1.00 57.97 ? 359 GLN D OE1 1 +ATOM 11842 N NE2 . GLN D 2 359 ? -73.972 -17.939 -89.669 1.00 51.05 ? 359 GLN D NE2 1 +ATOM 11843 N N . ILE D 2 360 ? -67.469 -16.642 -89.356 1.00 56.28 ? 360 ILE D N 1 +ATOM 11844 C CA . ILE D 2 360 ? -66.102 -16.707 -89.831 1.00 59.40 ? 360 ILE D CA 1 +ATOM 11845 C C . ILE D 2 360 ? -65.534 -18.130 -89.863 1.00 59.88 ? 360 ILE D C 1 +ATOM 11846 O O . ILE D 2 360 ? -64.777 -18.450 -90.791 1.00 61.73 ? 360 ILE D O 1 +ATOM 11847 C CB . ILE D 2 360 ? -65.202 -15.773 -88.990 1.00 56.07 ? 360 ILE D CB 1 +ATOM 11848 C CG1 . ILE D 2 360 ? -63.842 -16.407 -88.687 1.00 60.13 ? 360 ILE D CG1 1 +ATOM 11849 C CG2 . ILE D 2 360 ? -65.921 -15.374 -87.710 1.00 60.21 ? 360 ILE D CG2 1 +ATOM 11850 C CD1 . ILE D 2 360 ? -62.916 -15.528 -87.861 1.00 57.86 ? 360 ILE D CD1 1 +ATOM 11851 N N . GLU D 2 361 ? -65.916 -19.011 -88.927 1.00 52.17 ? 361 GLU D N 1 +ATOM 11852 C CA . GLU D 2 361 ? -65.437 -20.400 -88.871 1.00 47.54 ? 361 GLU D CA 1 +ATOM 11853 C C . GLU D 2 361 ? -63.973 -20.490 -88.420 1.00 46.84 ? 361 GLU D C 1 +ATOM 11854 O O . GLU D 2 361 ? -63.170 -19.600 -88.716 1.00 51.94 ? 361 GLU D O 1 +ATOM 11855 C CB . GLU D 2 361 ? -65.637 -21.082 -90.237 1.00 52.48 ? 361 GLU D CB 1 +ATOM 11856 C CG . GLU D 2 361 ? -65.049 -22.485 -90.393 1.00 56.80 ? 361 GLU D CG 1 +ATOM 11857 C CD . GLU D 2 361 ? -65.251 -23.091 -91.792 1.00 58.44 ? 361 GLU D CD 1 +ATOM 11858 O OE1 . GLU D 2 361 ? -64.321 -23.760 -92.300 1.00 53.27 ? 361 GLU D OE1 1 +ATOM 11859 O OE2 . GLU D 2 361 ? -66.354 -22.935 -92.368 1.00 59.18 ? 361 GLU D OE2 1 +ATOM 11860 N N . GLY D 2 362 ? -63.619 -21.550 -87.700 1.00 49.99 ? 362 GLY D N 1 +ATOM 11861 C CA . GLY D 2 362 ? -62.264 -21.710 -87.205 1.00 43.63 ? 362 GLY D CA 1 +ATOM 11862 C C . GLY D 2 362 ? -62.151 -22.916 -86.296 1.00 44.05 ? 362 GLY D C 1 +ATOM 11863 O O . GLY D 2 362 ? -63.112 -23.664 -86.091 1.00 45.87 ? 362 GLY D O 1 +ATOM 11864 N N . SER D 2 363 ? -60.947 -23.096 -85.750 1.00 41.55 ? 363 SER D N 1 +ATOM 11865 C CA . SER D 2 363 ? -60.650 -24.228 -84.882 1.00 43.71 ? 363 SER D CA 1 +ATOM 11866 C C . SER D 2 363 ? -60.301 -23.772 -83.469 1.00 46.04 ? 363 SER D C 1 +ATOM 11867 O O . SER D 2 363 ? -59.632 -22.754 -83.271 1.00 42.13 ? 363 SER D O 1 +ATOM 11868 C CB . SER D 2 363 ? -59.480 -25.038 -85.409 1.00 45.57 ? 363 SER D CB 1 +ATOM 11869 O OG . SER D 2 363 ? -58.293 -24.276 -85.295 1.00 45.62 ? 363 SER D OG 1 +ATOM 11870 N N . LEU D 2 364 ? -60.697 -24.582 -82.488 1.00 48.28 ? 364 LEU D N 1 +ATOM 11871 C CA . LEU D 2 364 ? -60.453 -24.311 -81.071 1.00 46.66 ? 364 LEU D CA 1 +ATOM 11872 C C . LEU D 2 364 ? -59.541 -25.402 -80.522 1.00 53.73 ? 364 LEU D C 1 +ATOM 11873 O O . LEU D 2 364 ? -60.011 -26.488 -80.168 1.00 55.58 ? 364 LEU D O 1 +ATOM 11874 C CB . LEU D 2 364 ? -61.761 -24.273 -80.287 1.00 46.45 ? 364 LEU D CB 1 +ATOM 11875 C CG . LEU D 2 364 ? -62.585 -22.991 -80.253 1.00 46.97 ? 364 LEU D CG 1 +ATOM 11876 C CD1 . LEU D 2 364 ? -61.696 -21.846 -79.815 1.00 49.15 ? 364 LEU D CD1 1 +ATOM 11877 C CD2 . LEU D 2 364 ? -63.252 -22.711 -81.592 1.00 48.71 ? 364 LEU D CD2 1 +ATOM 11878 N N . ALA D 2 365 ? -58.247 -25.116 -80.413 1.00 56.29 ? 365 ALA D N 1 +ATOM 11879 C CA . ALA D 2 365 ? -57.301 -26.067 -79.843 1.00 50.37 ? 365 ALA D CA 1 +ATOM 11880 C C . ALA D 2 365 ? -57.292 -25.898 -78.331 1.00 48.47 ? 365 ALA D C 1 +ATOM 11881 O O . ALA D 2 365 ? -57.017 -24.802 -77.832 1.00 54.30 ? 365 ALA D O 1 +ATOM 11882 C CB . ALA D 2 365 ? -55.899 -25.861 -80.418 1.00 54.97 ? 365 ALA D CB 1 +ATOM 11883 N N . ALA D 2 366 ? -57.593 -26.975 -77.608 1.00 51.32 ? 366 ALA D N 1 +ATOM 11884 C CA . ALA D 2 366 ? -57.636 -26.913 -76.152 1.00 50.92 ? 366 ALA D CA 1 +ATOM 11885 C C . ALA D 2 366 ? -56.297 -26.450 -75.593 1.00 49.07 ? 366 ALA D C 1 +ATOM 11886 O O . ALA D 2 366 ? -55.233 -26.692 -76.171 1.00 48.73 ? 366 ALA D O 1 +ATOM 11887 C CB . ALA D 2 366 ? -58.002 -28.274 -75.560 1.00 49.04 ? 366 ALA D CB 1 +ATOM 11888 N N . PHE D 2 367 ? -56.358 -25.759 -74.463 1.00 48.14 ? 367 PHE D N 1 +ATOM 11889 C CA . PHE D 2 367 ? -55.171 -25.148 -73.888 1.00 51.28 ? 367 PHE D CA 1 +ATOM 11890 C C . PHE D 2 367 ? -54.447 -26.150 -73.002 1.00 54.62 ? 367 PHE D C 1 +ATOM 11891 O O . PHE D 2 367 ? -55.047 -26.733 -72.092 1.00 54.21 ? 367 PHE D O 1 +ATOM 11892 C CB . PHE D 2 367 ? -55.538 -23.897 -73.091 1.00 50.04 ? 367 PHE D CB 1 +ATOM 11893 C CG . PHE D 2 367 ? -54.764 -22.675 -73.497 1.00 54.27 ? 367 PHE D CG 1 +ATOM 11894 C CD1 . PHE D 2 367 ? -53.448 -22.782 -73.919 1.00 61.34 ? 367 PHE D CD1 1 +ATOM 11895 C CD2 . PHE D 2 367 ? -55.353 -21.422 -73.471 1.00 51.53 ? 367 PHE D CD2 1 +ATOM 11896 C CE1 . PHE D 2 367 ? -52.732 -21.661 -74.297 1.00 62.32 ? 367 PHE D CE1 1 +ATOM 11897 C CE2 . PHE D 2 367 ? -54.645 -20.299 -73.849 1.00 50.81 ? 367 PHE D CE2 1 +ATOM 11898 C CZ . PHE D 2 367 ? -53.333 -20.418 -74.262 1.00 57.36 ? 367 PHE D CZ 1 +ATOM 11899 N N . LEU D 2 368 ? -53.157 -26.348 -73.282 1.00 53.29 ? 368 LEU D N 1 +ATOM 11900 C CA . LEU D 2 368 ? -52.302 -27.124 -72.403 1.00 48.77 ? 368 LEU D CA 1 +ATOM 11901 C C . LEU D 2 368 ? -52.244 -26.452 -71.034 1.00 53.42 ? 368 LEU D C 1 +ATOM 11902 O O . LEU D 2 368 ? -52.453 -25.242 -70.923 1.00 55.18 ? 368 LEU D O 1 +ATOM 11903 C CB . LEU D 2 368 ? -50.900 -27.231 -72.998 1.00 49.53 ? 368 LEU D CB 1 +ATOM 11904 C CG . LEU D 2 368 ? -50.724 -28.198 -74.165 1.00 56.00 ? 368 LEU D CG 1 +ATOM 11905 C CD1 . LEU D 2 368 ? -49.265 -28.220 -74.611 1.00 53.13 ? 368 LEU D CD1 1 +ATOM 11906 C CD2 . LEU D 2 368 ? -51.207 -29.592 -73.780 1.00 56.57 ? 368 LEU D CD2 1 +ATOM 11907 N N . PRO D 2 369 ? -51.958 -27.210 -69.973 1.00 53.89 ? 369 PRO D N 1 +ATOM 11908 C CA . PRO D 2 369 ? -51.983 -26.615 -68.634 1.00 51.16 ? 369 PRO D CA 1 +ATOM 11909 C C . PRO D 2 369 ? -50.938 -25.514 -68.512 1.00 59.11 ? 369 PRO D C 1 +ATOM 11910 O O . PRO D 2 369 ? -49.932 -25.500 -69.228 1.00 56.26 ? 369 PRO D O 1 +ATOM 11911 C CB . PRO D 2 369 ? -51.674 -27.797 -67.712 1.00 49.54 ? 369 PRO D CB 1 +ATOM 11912 C CG . PRO D 2 369 ? -50.916 -28.734 -68.559 1.00 52.09 ? 369 PRO D CG 1 +ATOM 11913 C CD . PRO D 2 369 ? -51.492 -28.607 -69.934 1.00 56.27 ? 369 PRO D CD 1 +ATOM 11914 N N . ASP D 2 370 ? -51.196 -24.590 -67.584 1.00 58.48 ? 370 ASP D N 1 +ATOM 11915 C CA . ASP D 2 370 ? -50.375 -23.394 -67.430 1.00 52.06 ? 370 ASP D CA 1 +ATOM 11916 C C . ASP D 2 370 ? -48.907 -23.739 -67.223 1.00 51.06 ? 370 ASP D C 1 +ATOM 11917 O O . ASP D 2 370 ? -48.566 -24.581 -66.390 1.00 53.76 ? 370 ASP D O 1 +ATOM 11918 C CB . ASP D 2 370 ? -50.875 -22.568 -66.246 1.00 50.33 ? 370 ASP D CB 1 +ATOM 11919 C CG . ASP D 2 370 ? -50.216 -21.210 -66.174 1.00 60.41 ? 370 ASP D CG 1 +ATOM 11920 O OD1 . ASP D 2 370 ? -49.733 -20.739 -67.226 1.00 65.80 ? 370 ASP D OD1 1 +ATOM 11921 O OD2 . ASP D 2 370 ? -50.159 -20.622 -65.074 1.00 56.21 ? 370 ASP D OD2 1 +ATOM 11922 N N . LEU D 2 371 ? -48.034 -23.059 -67.972 1.00 47.77 ? 371 LEU D N 1 +ATOM 11923 C CA . LEU D 2 371 ? -46.603 -23.341 -67.922 1.00 49.73 ? 371 LEU D CA 1 +ATOM 11924 C C . LEU D 2 371 ? -46.002 -23.147 -66.539 1.00 48.89 ? 371 LEU D C 1 +ATOM 11925 O O . LEU D 2 371 ? -44.820 -23.456 -66.353 1.00 46.60 ? 371 LEU D O 1 +ATOM 11926 C CB . LEU D 2 371 ? -45.845 -22.468 -68.918 1.00 42.24 ? 371 LEU D CB 1 +ATOM 11927 C CG . LEU D 2 371 ? -46.046 -22.794 -70.392 1.00 46.56 ? 371 LEU D CG 1 +ATOM 11928 C CD1 . LEU D 2 371 ? -47.250 -22.045 -70.945 1.00 52.58 ? 371 LEU D CD1 1 +ATOM 11929 C CD2 . LEU D 2 371 ? -44.775 -22.483 -71.172 1.00 38.43 ? 371 LEU D CD2 1 +ATOM 11930 N N . ALA D 2 372 ? -46.759 -22.605 -65.585 1.00 48.43 ? 372 ALA D N 1 +ATOM 11931 C CA . ALA D 2 372 ? -46.228 -22.400 -64.244 1.00 51.92 ? 372 ALA D CA 1 +ATOM 11932 C C . ALA D 2 372 ? -46.079 -23.722 -63.494 1.00 56.53 ? 372 ALA D C 1 +ATOM 11933 O O . ALA D 2 372 ? -45.029 -23.993 -62.897 1.00 50.35 ? 372 ALA D O 1 +ATOM 11934 C CB . ALA D 2 372 ? -47.129 -21.435 -63.478 1.00 54.66 ? 372 ALA D CB 1 +ATOM 11935 N N . LEU D 2 373 ? -47.116 -24.564 -63.524 1.00 57.57 ? 373 LEU D N 1 +ATOM 11936 C CA . LEU D 2 373 ? -47.109 -25.866 -62.866 1.00 52.95 ? 373 LEU D CA 1 +ATOM 11937 C C . LEU D 2 373 ? -46.940 -27.027 -63.839 1.00 54.50 ? 373 LEU D C 1 +ATOM 11938 O O . LEU D 2 373 ? -47.178 -28.180 -63.463 1.00 58.42 ? 373 LEU D O 1 +ATOM 11939 C CB . LEU D 2 373 ? -48.393 -26.057 -62.054 1.00 43.74 ? 373 LEU D CB 1 +ATOM 11940 C CG . LEU D 2 373 ? -49.741 -25.597 -62.615 1.00 43.52 ? 373 LEU D CG 1 +ATOM 11941 C CD1 . LEU D 2 373 ? -50.089 -26.252 -63.938 1.00 46.84 ? 373 LEU D CD1 1 +ATOM 11942 C CD2 . LEU D 2 373 ? -50.823 -25.896 -61.599 1.00 55.22 ? 373 LEU D CD2 1 +ATOM 11943 N N . ALA D 2 374 ? -46.560 -26.748 -65.079 1.00 54.13 ? 374 ALA D N 1 +ATOM 11944 C CA . ALA D 2 374 ? -46.363 -27.767 -66.094 1.00 50.85 ? 374 ALA D CA 1 +ATOM 11945 C C . ALA D 2 374 ? -45.370 -27.228 -67.121 1.00 52.50 ? 374 ALA D C 1 +ATOM 11946 O O . ALA D 2 374 ? -45.669 -27.100 -68.311 1.00 48.59 ? 374 ALA D O 1 +ATOM 11947 C CB . ALA D 2 374 ? -47.697 -28.153 -66.729 1.00 49.20 ? 374 ALA D CB 1 +ATOM 11948 N N . LYS D 2 375 ? -44.164 -26.906 -66.649 1.00 47.98 ? 375 LYS D N 1 +ATOM 11949 C CA . LYS D 2 375 ? -43.137 -26.354 -67.523 1.00 55.11 ? 375 LYS D CA 1 +ATOM 11950 C C . LYS D 2 375 ? -42.882 -27.273 -68.710 1.00 54.65 ? 375 LYS D C 1 +ATOM 11951 O O . LYS D 2 375 ? -42.886 -28.499 -68.580 1.00 61.10 ? 375 LYS D O 1 +ATOM 11952 C CB . LYS D 2 375 ? -41.836 -26.117 -66.746 1.00 63.16 ? 375 LYS D CB 1 +ATOM 11953 C CG . LYS D 2 375 ? -41.711 -24.725 -66.102 1.00 73.13 ? 375 LYS D CG 1 +ATOM 11954 C CD . LYS D 2 375 ? -42.299 -24.671 -64.691 1.00 74.28 ? 375 LYS D CD 1 +ATOM 11955 C CE . LYS D 2 375 ? -42.103 -23.297 -64.043 1.00 67.50 ? 375 LYS D CE 1 +ATOM 11956 N NZ . LYS D 2 375 ? -42.719 -22.192 -64.839 1.00 67.62 ? 375 LYS D NZ 1 +ATOM 11957 N N . ARG D 2 376 ? -42.670 -26.670 -69.879 1.00 51.76 ? 376 ARG D N 1 +ATOM 11958 C CA . ARG D 2 376 ? -42.436 -27.407 -71.113 1.00 48.60 ? 376 ARG D CA 1 +ATOM 11959 C C . ARG D 2 376 ? -41.075 -27.031 -71.675 1.00 52.06 ? 376 ARG D C 1 +ATOM 11960 O O . ARG D 2 376 ? -40.833 -25.862 -71.992 1.00 59.88 ? 376 ARG D O 1 +ATOM 11961 C CB . ARG D 2 376 ? -43.528 -27.130 -72.149 1.00 42.05 ? 376 ARG D CB 1 +ATOM 11962 C CG . ARG D 2 376 ? -44.925 -27.269 -71.606 1.00 43.10 ? 376 ARG D CG 1 +ATOM 11963 C CD . ARG D 2 376 ? -45.919 -27.480 -72.731 1.00 49.47 ? 376 ARG D CD 1 +ATOM 11964 N NE . ARG D 2 376 ? -47.094 -26.630 -72.597 1.00 56.86 ? 376 ARG D NE 1 +ATOM 11965 C CZ . ARG D 2 376 ? -47.258 -25.486 -73.246 1.00 51.22 ? 376 ARG D CZ 1 +ATOM 11966 N NH1 . ARG D 2 376 ? -46.316 -25.069 -74.081 1.00 58.55 ? 376 ARG D NH1 1 +ATOM 11967 N NH2 . ARG D 2 376 ? -48.360 -24.766 -73.064 1.00 44.24 ? 376 ARG D NH2 1 +ATOM 11968 N N . LYS D 2 377 ? -40.194 -28.017 -71.794 1.00 50.25 ? 377 LYS D N 1 +ATOM 11969 C CA . LYS D 2 377 ? -38.964 -27.817 -72.539 1.00 50.07 ? 377 LYS D CA 1 +ATOM 11970 C C . LYS D 2 377 ? -39.298 -27.568 -74.003 1.00 47.71 ? 377 LYS D C 1 +ATOM 11971 O O . LYS D 2 377 ? -40.356 -27.952 -74.502 1.00 49.05 ? 377 LYS D O 1 +ATOM 11972 C CB . LYS D 2 377 ? -38.049 -29.036 -72.414 1.00 56.35 ? 377 LYS D CB 1 +ATOM 11973 C CG . LYS D 2 377 ? -36.574 -28.800 -72.764 1.00 53.11 ? 377 LYS D CG 1 +ATOM 11974 C CD . LYS D 2 377 ? -35.842 -28.058 -71.654 1.00 59.87 ? 377 LYS D CD 1 +ATOM 11975 C CE . LYS D 2 377 ? -34.359 -28.409 -71.641 1.00 47.62 ? 377 LYS D CE 1 +ATOM 11976 N NZ . LYS D 2 377 ? -33.689 -28.083 -72.923 1.00 40.04 ? 377 LYS D NZ 1 +ATOM 11977 N N . THR D 2 378 ? -38.382 -26.913 -74.699 1.00 48.83 ? 378 THR D N 1 +ATOM 11978 C CA . THR D 2 378 ? -38.562 -26.633 -76.116 1.00 53.24 ? 378 THR D CA 1 +ATOM 11979 C C . THR D 2 378 ? -37.262 -26.979 -76.828 1.00 52.86 ? 378 THR D C 1 +ATOM 11980 O O . THR D 2 378 ? -36.229 -26.348 -76.585 1.00 56.20 ? 378 THR D O 1 +ATOM 11981 C CB . THR D 2 378 ? -38.973 -25.175 -76.339 1.00 59.65 ? 378 THR D CB 1 +ATOM 11982 O OG1 . THR D 2 378 ? -38.707 -24.796 -77.693 1.00 62.82 ? 378 THR D OG1 1 +ATOM 11983 C CG2 . THR D 2 378 ? -38.233 -24.243 -75.375 1.00 66.50 ? 378 THR D CG2 1 +ATOM 11984 N N . TRP D 2 379 ? -37.307 -27.991 -77.688 1.00 49.89 ? 379 TRP D N 1 +ATOM 11985 C CA . TRP D 2 379 ? -36.122 -28.508 -78.352 1.00 47.99 ? 379 TRP D CA 1 +ATOM 11986 C C . TRP D 2 379 ? -36.090 -28.062 -79.805 1.00 47.54 ? 379 TRP D C 1 +ATOM 11987 O O . TRP D 2 379 ? -37.130 -27.903 -80.449 1.00 46.13 ? 379 TRP D O 1 +ATOM 11988 C CB . TRP D 2 379 ? -36.072 -30.035 -78.295 1.00 52.65 ? 379 TRP D CB 1 +ATOM 11989 C CG . TRP D 2 379 ? -36.203 -30.611 -76.927 1.00 55.00 ? 379 TRP D CG 1 +ATOM 11990 C CD1 . TRP D 2 379 ? -37.336 -30.687 -76.178 1.00 55.63 ? 379 TRP D CD1 1 +ATOM 11991 C CD2 . TRP D 2 379 ? -35.164 -31.216 -76.149 1.00 54.72 ? 379 TRP D CD2 1 +ATOM 11992 N NE1 . TRP D 2 379 ? -37.068 -31.293 -74.975 1.00 54.86 ? 379 TRP D NE1 1 +ATOM 11993 C CE2 . TRP D 2 379 ? -35.740 -31.627 -74.933 1.00 51.45 ? 379 TRP D CE2 1 +ATOM 11994 C CE3 . TRP D 2 379 ? -33.802 -31.446 -76.361 1.00 54.67 ? 379 TRP D CE3 1 +ATOM 11995 C CZ2 . TRP D 2 379 ? -35.003 -32.252 -73.934 1.00 52.60 ? 379 TRP D CZ2 1 +ATOM 11996 C CZ3 . TRP D 2 379 ? -33.073 -32.068 -75.367 1.00 55.30 ? 379 TRP D CZ3 1 +ATOM 11997 C CH2 . TRP D 2 379 ? -33.673 -32.463 -74.169 1.00 55.25 ? 379 TRP D CH2 1 +ATOM 11998 N N . ARG D 2 380 ? -34.877 -27.880 -80.316 1.00 47.56 ? 380 ARG D N 1 +ATOM 11999 C CA . ARG D 2 380 ? -34.664 -27.467 -81.696 1.00 51.06 ? 380 ARG D CA 1 +ATOM 12000 C C . ARG D 2 380 ? -34.499 -28.716 -82.550 1.00 52.71 ? 380 ARG D C 1 +ATOM 12001 O O . ARG D 2 380 ? -33.645 -29.561 -82.263 1.00 58.77 ? 380 ARG D O 1 +ATOM 12002 C CB . ARG D 2 380 ? -33.439 -26.559 -81.804 1.00 59.76 ? 380 ARG D CB 1 +ATOM 12003 C CG . ARG D 2 380 ? -32.993 -26.237 -83.231 1.00 66.36 ? 380 ARG D CG 1 +ATOM 12004 C CD . ARG D 2 380 ? -31.650 -25.504 -83.237 1.00 72.56 ? 380 ARG D CD 1 +ATOM 12005 N NE . ARG D 2 380 ? -31.543 -24.524 -84.318 1.00 77.98 ? 380 ARG D NE 1 +ATOM 12006 C CZ . ARG D 2 380 ? -30.879 -24.737 -85.450 1.00 70.73 ? 380 ARG D CZ 1 +ATOM 12007 N NH1 . ARG D 2 380 ? -30.268 -25.897 -85.640 1.00 69.23 ? 380 ARG D NH1 1 +ATOM 12008 N NH2 . ARG D 2 380 ? -30.820 -23.798 -86.387 1.00 64.32 ? 380 ARG D NH2 1 +ATOM 12009 N N . ASN D 2 381 ? -35.318 -28.833 -83.587 1.00 52.82 ? 381 ASN D N 1 +ATOM 12010 C CA . ASN D 2 381 ? -35.272 -30.007 -84.445 1.00 55.93 ? 381 ASN D CA 1 +ATOM 12011 C C . ASN D 2 381 ? -33.920 -30.073 -85.147 1.00 58.28 ? 381 ASN D C 1 +ATOM 12012 O O . ASN D 2 381 ? -33.478 -29.070 -85.724 1.00 62.98 ? 381 ASN D O 1 +ATOM 12013 C CB . ASN D 2 381 ? -36.412 -29.947 -85.465 1.00 59.41 ? 381 ASN D CB 1 +ATOM 12014 C CG . ASN D 2 381 ? -36.586 -31.240 -86.246 1.00 56.17 ? 381 ASN D CG 1 +ATOM 12015 O OD1 . ASN D 2 381 ? -35.632 -31.982 -86.478 1.00 58.93 ? 381 ASN D OD1 1 +ATOM 12016 N ND2 . ASN D 2 381 ? -37.820 -31.519 -86.647 1.00 41.74 ? 381 ASN D ND2 1 +ATOM 12017 N N . PRO D 2 382 ? -33.227 -31.216 -85.112 1.00 50.99 ? 382 PRO D N 1 +ATOM 12018 C CA . PRO D 2 382 ? -31.958 -31.317 -85.848 1.00 52.99 ? 382 PRO D CA 1 +ATOM 12019 C C . PRO D 2 382 ? -32.131 -31.294 -87.350 1.00 50.83 ? 382 PRO D C 1 +ATOM 12020 O O . PRO D 2 382 ? -31.148 -31.065 -88.061 1.00 58.07 ? 382 PRO D O 1 +ATOM 12021 C CB . PRO D 2 382 ? -31.380 -32.655 -85.377 1.00 51.35 ? 382 PRO D CB 1 +ATOM 12022 C CG . PRO D 2 382 ? -32.554 -33.414 -84.917 1.00 50.10 ? 382 PRO D CG 1 +ATOM 12023 C CD . PRO D 2 382 ? -33.491 -32.420 -84.313 1.00 42.63 ? 382 PRO D CD 1 +ATOM 12024 N N . TRP D 2 383 ? -33.335 -31.544 -87.860 1.00 53.14 ? 383 TRP D N 1 +ATOM 12025 C CA . TRP D 2 383 ? -33.619 -31.382 -89.278 1.00 59.26 ? 383 TRP D CA 1 +ATOM 12026 C C . TRP D 2 383 ? -34.361 -30.082 -89.573 1.00 58.67 ? 383 TRP D C 1 +ATOM 12027 O O . TRP D 2 383 ? -35.022 -29.975 -90.610 1.00 62.05 ? 383 TRP D O 1 +ATOM 12028 C CB . TRP D 2 383 ? -34.396 -32.591 -89.803 1.00 57.61 ? 383 TRP D CB 1 +ATOM 12029 C CG . TRP D 2 383 ? -33.569 -33.851 -89.821 1.00 61.93 ? 383 TRP D CG 1 +ATOM 12030 C CD1 . TRP D 2 383 ? -32.747 -34.276 -90.824 1.00 59.83 ? 383 TRP D CD1 1 +ATOM 12031 C CD2 . TRP D 2 383 ? -33.469 -34.833 -88.780 1.00 59.75 ? 383 TRP D CD2 1 +ATOM 12032 N NE1 . TRP D 2 383 ? -32.150 -35.464 -90.478 1.00 57.86 ? 383 TRP D NE1 1 +ATOM 12033 C CE2 . TRP D 2 383 ? -32.575 -35.827 -89.228 1.00 56.52 ? 383 TRP D CE2 1 +ATOM 12034 C CE3 . TRP D 2 383 ? -34.052 -34.971 -87.518 1.00 59.25 ? 383 TRP D CE3 1 +ATOM 12035 C CZ2 . TRP D 2 383 ? -32.251 -36.941 -88.457 1.00 54.56 ? 383 TRP D CZ2 1 +ATOM 12036 C CZ3 . TRP D 2 383 ? -33.728 -36.078 -86.754 1.00 57.61 ? 383 TRP D CZ3 1 +ATOM 12037 C CH2 . TRP D 2 383 ? -32.836 -37.046 -87.225 1.00 57.75 ? 383 TRP D CH2 1 +ATOM 12038 N N . ARG D 2 384 ? -34.240 -29.088 -88.690 1.00 57.68 ? 384 ARG D N 1 +ATOM 12039 C CA . ARG D 2 384 ? -34.919 -27.808 -88.864 1.00 61.97 ? 384 ARG D CA 1 +ATOM 12040 C C . ARG D 2 384 ? -34.413 -27.086 -90.106 1.00 61.52 ? 384 ARG D C 1 +ATOM 12041 O O . ARG D 2 384 ? -33.207 -26.894 -90.280 1.00 61.44 ? 384 ARG D O 1 +ATOM 12042 C CB . ARG D 2 384 ? -34.704 -26.936 -87.622 1.00 63.42 ? 384 ARG D CB 1 +ATOM 12043 C CG . ARG D 2 384 ? -35.163 -25.482 -87.749 1.00 74.95 ? 384 ARG D CG 1 +ATOM 12044 C CD . ARG D 2 384 ? -34.561 -24.592 -86.649 1.00 72.74 ? 384 ARG D CD 1 +ATOM 12045 N NE . ARG D 2 384 ? -35.279 -23.322 -86.504 1.00 77.26 ? 384 ARG D NE 1 +ATOM 12046 C CZ . ARG D 2 384 ? -34.834 -22.142 -86.932 1.00 75.73 ? 384 ARG D CZ 1 +ATOM 12047 N NH1 . ARG D 2 384 ? -33.655 -22.050 -87.535 1.00 66.74 ? 384 ARG D NH1 1 +ATOM 12048 N NH2 . ARG D 2 384 ? -35.569 -21.050 -86.753 1.00 69.82 ? 384 ARG D NH2 1 +ATOM 12049 N N . ARG D 2 385 ? -35.340 -26.695 -90.978 1.00 58.52 ? 385 ARG D N 1 +ATOM 12050 C CA . ARG D 2 385 ? -34.973 -25.958 -92.180 1.00 61.96 ? 385 ARG D CA 1 +ATOM 12051 C C . ARG D 2 385 ? -34.333 -24.620 -91.826 1.00 68.09 ? 385 ARG D C 1 +ATOM 12052 O O . ARG D 2 385 ? -34.598 -24.038 -90.772 1.00 73.40 ? 385 ARG D O 1 +ATOM 12053 C CB . ARG D 2 385 ? -36.196 -25.743 -93.065 1.00 64.48 ? 385 ARG D CB 1 +ATOM 12054 C CG . ARG D 2 385 ? -36.645 -26.998 -93.782 1.00 57.98 ? 385 ARG D CG 1 +ATOM 12055 C CD . ARG D 2 385 ? -38.060 -26.856 -94.272 1.00 54.95 ? 385 ARG D CD 1 +ATOM 12056 N NE . ARG D 2 385 ? -38.710 -28.148 -94.429 1.00 49.57 ? 385 ARG D NE 1 +ATOM 12057 C CZ . ARG D 2 385 ? -38.535 -28.936 -95.481 1.00 51.58 ? 385 ARG D CZ 1 +ATOM 12058 N NH1 . ARG D 2 385 ? -37.722 -28.565 -96.458 1.00 51.56 ? 385 ARG D NH1 1 +ATOM 12059 N NH2 . ARG D 2 385 ? -39.172 -30.094 -95.553 1.00 60.75 ? 385 ARG D NH2 1 +ATOM 12060 N N . SER D 2 386 ? -33.459 -24.143 -92.719 1.00 66.08 ? 386 SER D N 1 +ATOM 12061 C CA . SER D 2 386 ? -32.720 -22.907 -92.474 1.00 70.50 ? 386 SER D CA 1 +ATOM 12062 C C . SER D 2 386 ? -33.616 -21.675 -92.408 1.00 73.49 ? 386 SER D C 1 +ATOM 12063 O O . SER D 2 386 ? -33.177 -20.638 -91.895 1.00 76.02 ? 386 SER D O 1 +ATOM 12064 C CB . SER D 2 386 ? -31.662 -22.703 -93.559 1.00 74.08 ? 386 SER D CB 1 +ATOM 12065 O OG . SER D 2 386 ? -32.267 -22.527 -94.828 1.00 78.68 ? 386 SER D OG 1 +ATOM 12066 N N . TYR D 2 387 ? -34.841 -21.756 -92.932 1.00 74.97 ? 387 TYR D N 1 +ATOM 12067 C CA . TYR D 2 387 ? -35.784 -20.633 -92.959 1.00 76.21 ? 387 TYR D CA 1 +ATOM 12068 C C . TYR D 2 387 ? -35.130 -19.388 -93.551 1.00 81.12 ? 387 TYR D C 1 +ATOM 12069 O O . TYR D 2 387 ? -35.226 -18.283 -93.012 1.00 88.67 ? 387 TYR D O 1 +ATOM 12070 C CB . TYR D 2 387 ? -36.356 -20.347 -91.567 1.00 77.91 ? 387 TYR D CB 1 +ATOM 12071 C CG . TYR D 2 387 ? -37.259 -21.444 -91.055 1.00 74.14 ? 387 TYR D CG 1 +ATOM 12072 C CD1 . TYR D 2 387 ? -38.308 -21.922 -91.826 1.00 71.41 ? 387 TYR D CD1 1 +ATOM 12073 C CD2 . TYR D 2 387 ? -37.045 -22.018 -89.812 1.00 74.75 ? 387 TYR D CD2 1 +ATOM 12074 C CE1 . TYR D 2 387 ? -39.124 -22.938 -91.374 1.00 79.15 ? 387 TYR D CE1 1 +ATOM 12075 C CE2 . TYR D 2 387 ? -37.854 -23.032 -89.348 1.00 79.64 ? 387 TYR D CE2 1 +ATOM 12076 C CZ . TYR D 2 387 ? -38.894 -23.490 -90.132 1.00 83.45 ? 387 TYR D CZ 1 +ATOM 12077 O OH . TYR D 2 387 ? -39.706 -24.503 -89.671 1.00 94.06 ? 387 TYR D OH 1 +ATOM 12078 N N . HIS D 2 388 ? -34.476 -19.577 -94.696 1.00 84.41 ? 388 HIS D N 1 +ATOM 12079 C CA . HIS D 2 388 ? -33.761 -18.505 -95.376 1.00 87.63 ? 388 HIS D CA 1 +ATOM 12080 C C . HIS D 2 388 ? -33.609 -18.903 -96.835 1.00 85.32 ? 388 HIS D C 1 +ATOM 12081 O O . HIS D 2 388 ? -33.127 -20.000 -97.129 1.00 84.56 ? 388 HIS D O 1 +ATOM 12082 C CB . HIS D 2 388 ? -32.385 -18.258 -94.736 1.00 86.37 ? 388 HIS D CB 1 +ATOM 12083 C CG . HIS D 2 388 ? -32.395 -17.236 -93.638 1.00 100.87 ? 388 HIS D CG 1 +ATOM 12084 N ND1 . HIS D 2 388 ? -33.293 -16.190 -93.602 1.00 113.63 ? 388 HIS D ND1 1 +ATOM 12085 C CD2 . HIS D 2 388 ? -31.631 -17.113 -92.525 1.00 98.15 ? 388 HIS D CD2 1 +ATOM 12086 C CE1 . HIS D 2 388 ? -33.075 -15.462 -92.521 1.00 110.77 ? 388 HIS D CE1 1 +ATOM 12087 N NE2 . HIS D 2 388 ? -32.072 -16.001 -91.849 1.00 99.91 ? 388 HIS D NE2 1 +ATOM 12088 N N . LYS D 2 389 ? -34.048 -18.027 -97.738 1.00 87.32 ? 389 LYS D N 1 +ATOM 12089 C CA . LYS D 2 389 ? -33.898 -18.285 -99.164 1.00 85.09 ? 389 LYS D CA 1 +ATOM 12090 C C . LYS D 2 389 ? -32.421 -18.390 -99.540 1.00 92.32 ? 389 LYS D C 1 +ATOM 12091 O O . LYS D 2 389 ? -31.544 -17.852 -98.857 1.00 96.40 ? 389 LYS D O 1 +ATOM 12092 C CB . LYS D 2 389 ? -34.583 -17.186 -99.987 1.00 81.39 ? 389 LYS D CB 1 +ATOM 12093 C CG . LYS D 2 389 ? -35.097 -15.972 -99.189 1.00 81.78 ? 389 LYS D CG 1 +ATOM 12094 C CD . LYS D 2 389 ? -35.596 -14.861 -100.126 1.00 68.73 ? 389 LYS D CD 1 +ATOM 12095 C CE . LYS D 2 389 ? -36.316 -13.755 -99.373 1.00 55.55 ? 389 LYS D CE 1 +ATOM 12096 N NZ . LYS D 2 389 ? -37.610 -14.232 -98.813 1.00 57.60 ? 389 LYS D NZ 1 +ATOM 12097 N N . ARG D 2 390 ? -32.155 -19.122 -100.628 1.00 89.88 ? 390 ARG D N 1 +ATOM 12098 C CA . ARG D 2 390 ? -30.817 -19.331 -101.186 1.00 92.90 ? 390 ARG D CA 1 +ATOM 12099 C C . ARG D 2 390 ? -29.991 -20.255 -100.294 1.00 85.07 ? 390 ARG D C 1 +ATOM 12100 O O . ARG D 2 390 ? -29.478 -21.280 -100.746 1.00 81.76 ? 390 ARG D O 1 +ATOM 12101 C CB . ARG D 2 390 ? -30.081 -17.998 -101.396 1.00 91.89 ? 390 ARG D CB 1 +ATOM 12102 C CG . ARG D 2 390 ? -30.734 -17.055 -102.409 1.00 90.96 ? 390 ARG D CG 1 +ATOM 12103 C CD . ARG D 2 390 ? -30.951 -15.677 -101.780 1.00 91.88 ? 390 ARG D CD 1 +ATOM 12104 N NE . ARG D 2 390 ? -31.658 -14.750 -102.663 1.00 89.06 ? 390 ARG D NE 1 +ATOM 12105 C CZ . ARG D 2 390 ? -32.149 -13.571 -102.281 1.00 85.52 ? 390 ARG D CZ 1 +ATOM 12106 N NH1 . ARG D 2 390 ? -32.020 -13.166 -101.023 1.00 75.12 ? 390 ARG D NH1 1 +ATOM 12107 N NH2 . ARG D 2 390 ? -32.774 -12.795 -103.158 1.00 75.71 ? 390 ARG D NH2 1 +ATOM 12108 N N . LYS D 2 391 ? -29.844 -19.878 -99.032 1.00 87.95 ? 391 LYS D N 1 +ATOM 12109 C CA . LYS D 2 391 ? -28.960 -20.568 -98.104 1.00 84.76 ? 391 LYS D CA 1 +ATOM 12110 C C . LYS D 2 391 ? -29.485 -21.965 -97.794 1.00 78.70 ? 391 LYS D C 1 +ATOM 12111 O O . LYS D 2 391 ? -30.647 -22.133 -97.415 1.00 88.22 ? 391 LYS D O 1 +ATOM 12112 C CB . LYS D 2 391 ? -28.836 -19.738 -96.833 1.00 90.12 ? 391 LYS D CB 1 +ATOM 12113 C CG . LYS D 2 391 ? -28.738 -18.236 -97.133 1.00 97.47 ? 391 LYS D CG 1 +ATOM 12114 C CD . LYS D 2 391 ? -29.156 -17.346 -95.963 1.00 97.58 ? 391 LYS D CD 1 +ATOM 12115 C CE . LYS D 2 391 ? -30.093 -16.247 -96.486 1.00 87.44 ? 391 LYS D CE 1 +ATOM 12116 N NZ . LYS D 2 391 ? -29.564 -15.528 -97.713 1.00 70.70 ? 391 LYS D NZ 1 +ATOM 12117 N N . LYS D 2 392 ? -28.635 -22.975 -97.980 1.00 71.53 ? 392 LYS D N 1 +ATOM 12118 C CA . LYS D 2 392 ? -29.042 -24.359 -97.777 1.00 71.09 ? 392 LYS D CA 1 +ATOM 12119 C C . LYS D 2 392 ? -29.022 -24.688 -96.285 1.00 59.38 ? 392 LYS D C 1 +ATOM 12120 O O . LYS D 2 392 ? -28.899 -23.809 -95.428 1.00 55.35 ? 392 LYS D O 1 +ATOM 12121 C CB . LYS D 2 392 ? -28.154 -25.295 -98.592 1.00 76.85 ? 392 LYS D CB 1 +ATOM 12122 C CG . LYS D 2 392 ? -28.907 -26.112 -99.647 1.00 74.05 ? 392 LYS D CG 1 +ATOM 12123 C CD . LYS D 2 392 ? -28.027 -27.203 -100.252 1.00 70.60 ? 392 LYS D CD 1 +ATOM 12124 C CE . LYS D 2 392 ? -26.957 -26.596 -101.146 1.00 83.57 ? 392 LYS D CE 1 +ATOM 12125 N NZ . LYS D 2 392 ? -26.147 -27.606 -101.880 1.00 83.60 ? 392 LYS D NZ 1 +ATOM 12126 N N . ALA D 2 393 ? -29.129 -25.977 -95.969 1.00 59.41 ? 393 ALA D N 1 +ATOM 12127 C CA . ALA D 2 393 ? -29.201 -26.459 -94.597 1.00 65.47 ? 393 ALA D CA 1 +ATOM 12128 C C . ALA D 2 393 ? -28.288 -27.668 -94.442 1.00 73.90 ? 393 ALA D C 1 +ATOM 12129 O O . ALA D 2 393 ? -27.920 -28.319 -95.421 1.00 84.02 ? 393 ALA D O 1 +ATOM 12130 C CB . ALA D 2 393 ? -30.639 -26.821 -94.203 1.00 66.07 ? 393 ALA D CB 1 +ATOM 12131 N N . GLU D 2 394 ? -27.925 -27.962 -93.188 1.00 70.72 ? 394 GLU D N 1 +ATOM 12132 C CA . GLU D 2 394 ? -26.932 -29.002 -92.922 1.00 76.16 ? 394 GLU D CA 1 +ATOM 12133 C C . GLU D 2 394 ? -27.408 -30.376 -93.385 1.00 71.99 ? 394 GLU D C 1 +ATOM 12134 O O . GLU D 2 394 ? -26.700 -31.072 -94.123 1.00 70.88 ? 394 GLU D O 1 +ATOM 12135 C CB . GLU D 2 394 ? -26.583 -29.027 -91.432 1.00 82.36 ? 394 GLU D CB 1 +ATOM 12136 C CG . GLU D 2 394 ? -25.081 -29.038 -91.150 1.00 85.48 ? 394 GLU D CG 1 +ATOM 12137 C CD . GLU D 2 394 ? -24.388 -30.301 -91.640 1.00 83.01 ? 394 GLU D CD 1 +ATOM 12138 O OE1 . GLU D 2 394 ? -24.314 -31.279 -90.866 1.00 67.24 ? 394 GLU D OE1 1 +ATOM 12139 O OE2 . GLU D 2 394 ? -23.920 -30.315 -92.800 1.00 91.52 ? 394 GLU D OE2 1 +ATOM 12140 N N . TRP D 2 395 ? -28.606 -30.786 -92.960 1.00 69.65 ? 395 TRP D N 1 +ATOM 12141 C CA . TRP D 2 395 ? -29.117 -32.111 -93.302 1.00 66.21 ? 395 TRP D CA 1 +ATOM 12142 C C . TRP D 2 395 ? -29.351 -32.292 -94.794 1.00 64.36 ? 395 TRP D C 1 +ATOM 12143 O O . TRP D 2 395 ? -29.597 -33.422 -95.228 1.00 67.99 ? 395 TRP D O 1 +ATOM 12144 C CB . TRP D 2 395 ? -30.413 -32.402 -92.535 1.00 70.03 ? 395 TRP D CB 1 +ATOM 12145 C CG . TRP D 2 395 ? -31.495 -31.355 -92.688 1.00 73.37 ? 395 TRP D CG 1 +ATOM 12146 C CD1 . TRP D 2 395 ? -31.569 -30.153 -92.045 1.00 71.13 ? 395 TRP D CD1 1 +ATOM 12147 C CD2 . TRP D 2 395 ? -32.651 -31.425 -93.536 1.00 67.37 ? 395 TRP D CD2 1 +ATOM 12148 N NE1 . TRP D 2 395 ? -32.697 -29.473 -92.438 1.00 67.29 ? 395 TRP D NE1 1 +ATOM 12149 C CE2 . TRP D 2 395 ? -33.376 -30.231 -93.354 1.00 66.29 ? 395 TRP D CE2 1 +ATOM 12150 C CE3 . TRP D 2 395 ? -33.140 -32.378 -94.433 1.00 66.81 ? 395 TRP D CE3 1 +ATOM 12151 C CZ2 . TRP D 2 395 ? -34.561 -29.966 -94.037 1.00 67.37 ? 395 TRP D CZ2 1 +ATOM 12152 C CZ3 . TRP D 2 395 ? -34.318 -32.112 -95.107 1.00 64.13 ? 395 TRP D CZ3 1 +ATOM 12153 C CH2 . TRP D 2 395 ? -35.014 -30.918 -94.906 1.00 66.92 ? 395 TRP D CH2 1 +ATOM 12154 N N . GLU D 2 396 ? -29.275 -31.225 -95.583 1.00 61.01 ? 396 GLU D N 1 +ATOM 12155 C CA . GLU D 2 396 ? -29.482 -31.299 -97.021 1.00 66.78 ? 396 GLU D CA 1 +ATOM 12156 C C . GLU D 2 396 ? -28.190 -31.503 -97.809 1.00 70.11 ? 396 GLU D C 1 +ATOM 12157 O O . GLU D 2 396 ? -28.212 -31.408 -99.040 1.00 69.63 ? 396 GLU D O 1 +ATOM 12158 C CB . GLU D 2 396 ? -30.200 -30.040 -97.516 1.00 73.64 ? 396 GLU D CB 1 +ATOM 12159 C CG . GLU D 2 396 ? -31.626 -29.889 -96.996 1.00 64.93 ? 396 GLU D CG 1 +ATOM 12160 C CD . GLU D 2 396 ? -32.334 -28.669 -97.565 1.00 68.41 ? 396 GLU D CD 1 +ATOM 12161 O OE1 . GLU D 2 396 ? -31.663 -27.803 -98.168 1.00 68.09 ? 396 GLU D OE1 1 +ATOM 12162 O OE2 . GLU D 2 396 ? -33.573 -28.595 -97.435 1.00 66.57 ? 396 GLU D OE2 1 +ATOM 12163 N N . VAL D 2 397 ? -27.069 -31.758 -97.135 1.00 72.52 ? 397 VAL D N 1 +ATOM 12164 C CA . VAL D 2 397 ? -25.805 -31.998 -97.826 1.00 70.59 ? 397 VAL D CA 1 +ATOM 12165 C C . VAL D 2 397 ? -25.038 -33.196 -97.286 1.00 73.42 ? 397 VAL D C 1 +ATOM 12166 O O . VAL D 2 397 ? -24.193 -33.758 -98.007 1.00 78.48 ? 397 VAL D O 1 +ATOM 12167 C CB . VAL D 2 397 ? -24.920 -30.734 -97.782 1.00 68.35 ? 397 VAL D CB 1 +ATOM 12168 C CG1 . VAL D 2 397 ? -24.295 -30.566 -96.395 1.00 71.63 ? 397 VAL D CG1 1 +ATOM 12169 C CG2 . VAL D 2 397 ? -23.863 -30.778 -98.881 1.00 57.13 ? 397 VAL D CG2 1 +ATOM 12170 N N . ASP D 2 398 ? -25.272 -33.631 -96.052 1.00 74.40 ? 398 ASP D N 1 +ATOM 12171 C CA . ASP D 2 398 ? -24.602 -34.793 -95.484 1.00 75.49 ? 398 ASP D CA 1 +ATOM 12172 C C . ASP D 2 398 ? -25.587 -35.952 -95.445 1.00 81.11 ? 398 ASP D C 1 +ATOM 12173 O O . ASP D 2 398 ? -26.549 -35.909 -94.661 1.00 84.04 ? 398 ASP D O 1 +ATOM 12174 C CB . ASP D 2 398 ? -24.086 -34.482 -94.077 1.00 76.16 ? 398 ASP D CB 1 +ATOM 12175 C CG . ASP D 2 398 ? -23.203 -35.588 -93.516 1.00 84.76 ? 398 ASP D CG 1 +ATOM 12176 O OD1 . ASP D 2 398 ? -23.625 -36.765 -93.527 1.00 82.15 ? 398 ASP D OD1 1 +ATOM 12177 O OD2 . ASP D 2 398 ? -22.092 -35.276 -93.035 1.00 95.64 ? 398 ASP D OD2 1 +ATOM 12178 N N . PRO D 2 399 ? -25.403 -37.000 -96.253 1.00 82.72 ? 399 PRO D N 1 +ATOM 12179 C CA . PRO D 2 399 ? -26.365 -38.114 -96.244 1.00 81.16 ? 399 PRO D CA 1 +ATOM 12180 C C . PRO D 2 399 ? -26.263 -39.001 -95.016 1.00 81.20 ? 399 PRO D C 1 +ATOM 12181 O O . PRO D 2 399 ? -27.194 -39.774 -94.755 1.00 81.53 ? 399 PRO D O 1 +ATOM 12182 C CB . PRO D 2 399 ? -26.009 -38.889 -97.516 1.00 84.37 ? 399 PRO D CB 1 +ATOM 12183 C CG . PRO D 2 399 ? -24.544 -38.633 -97.693 1.00 89.07 ? 399 PRO D CG 1 +ATOM 12184 C CD . PRO D 2 399 ? -24.284 -37.238 -97.181 1.00 84.36 ? 399 PRO D CD 1 +ATOM 12185 N N . ASP D 2 400 ? -25.176 -38.908 -94.252 1.00 77.44 ? 400 ASP D N 1 +ATOM 12186 C CA . ASP D 2 400 ? -25.006 -39.663 -93.018 1.00 78.32 ? 400 ASP D CA 1 +ATOM 12187 C C . ASP D 2 400 ? -25.294 -38.811 -91.790 1.00 81.62 ? 400 ASP D C 1 +ATOM 12188 O O . ASP D 2 400 ? -24.807 -39.124 -90.700 1.00 87.09 ? 400 ASP D O 1 +ATOM 12189 C CB . ASP D 2 400 ? -23.593 -40.243 -92.934 1.00 87.34 ? 400 ASP D CB 1 +ATOM 12190 C CG . ASP D 2 400 ? -23.252 -41.135 -94.115 1.00 87.65 ? 400 ASP D CG 1 +ATOM 12191 O OD1 . ASP D 2 400 ? -24.189 -41.642 -94.763 1.00 97.31 ? 400 ASP D OD1 1 +ATOM 12192 O OD2 . ASP D 2 400 ? -22.049 -41.331 -94.397 1.00 79.11 ? 400 ASP D OD2 1 +ATOM 12193 N N . TYR D 2 401 ? -26.045 -37.718 -91.966 1.00 76.54 ? 401 TYR D N 1 +ATOM 12194 C CA . TYR D 2 401 ? -26.363 -36.809 -90.868 1.00 75.83 ? 401 TYR D CA 1 +ATOM 12195 C C . TYR D 2 401 ? -26.822 -37.569 -89.628 1.00 79.56 ? 401 TYR D C 1 +ATOM 12196 O O . TYR D 2 401 ? -26.359 -37.296 -88.513 1.00 80.07 ? 401 TYR D O 1 +ATOM 12197 C CB . TYR D 2 401 ? -27.430 -35.805 -91.321 1.00 75.16 ? 401 TYR D CB 1 +ATOM 12198 C CG . TYR D 2 401 ? -27.710 -34.670 -90.350 1.00 73.42 ? 401 TYR D CG 1 +ATOM 12199 C CD1 . TYR D 2 401 ? -28.431 -34.885 -89.181 1.00 75.31 ? 401 TYR D CD1 1 +ATOM 12200 C CD2 . TYR D 2 401 ? -27.262 -33.380 -90.609 1.00 73.24 ? 401 TYR D CD2 1 +ATOM 12201 C CE1 . TYR D 2 401 ? -28.688 -33.859 -88.294 1.00 71.36 ? 401 TYR D CE1 1 +ATOM 12202 C CE2 . TYR D 2 401 ? -27.520 -32.341 -89.724 1.00 72.74 ? 401 TYR D CE2 1 +ATOM 12203 C CZ . TYR D 2 401 ? -28.233 -32.591 -88.568 1.00 71.34 ? 401 TYR D CZ 1 +ATOM 12204 O OH . TYR D 2 401 ? -28.497 -31.580 -87.672 1.00 72.01 ? 401 TYR D OH 1 +ATOM 12205 N N . CYS D 2 402 ? -27.722 -38.542 -89.805 1.00 74.24 ? 402 CYS D N 1 +ATOM 12206 C CA . CYS D 2 402 ? -28.288 -39.234 -88.651 1.00 73.59 ? 402 CYS D CA 1 +ATOM 12207 C C . CYS D 2 402 ? -27.217 -39.948 -87.835 1.00 83.12 ? 402 CYS D C 1 +ATOM 12208 O O . CYS D 2 402 ? -27.328 -40.027 -86.606 1.00 84.34 ? 402 CYS D O 1 +ATOM 12209 C CB . CYS D 2 402 ? -29.358 -40.225 -89.109 1.00 70.23 ? 402 CYS D CB 1 +ATOM 12210 S SG . CYS D 2 402 ? -30.150 -41.118 -87.747 1.00 78.69 ? 402 CYS D SG 1 +ATOM 12211 N N . ASP D 2 403 ? -26.150 -40.424 -88.486 1.00 88.00 ? 403 ASP D N 1 +ATOM 12212 C CA . ASP D 2 403 ? -25.074 -41.096 -87.764 1.00 87.23 ? 403 ASP D CA 1 +ATOM 12213 C C . ASP D 2 403 ? -24.319 -40.146 -86.852 1.00 90.14 ? 403 ASP D C 1 +ATOM 12214 O O . ASP D 2 403 ? -23.662 -40.600 -85.910 1.00 96.13 ? 403 ASP D O 1 +ATOM 12215 C CB . ASP D 2 403 ? -24.100 -41.748 -88.748 1.00 84.20 ? 403 ASP D CB 1 +ATOM 12216 C CG . ASP D 2 403 ? -24.788 -42.715 -89.695 1.00 96.50 ? 403 ASP D CG 1 +ATOM 12217 O OD1 . ASP D 2 403 ? -25.895 -43.188 -89.360 1.00 93.01 ? 403 ASP D OD1 1 +ATOM 12218 O OD2 . ASP D 2 403 ? -24.225 -42.996 -90.778 1.00 93.12 ? 403 ASP D OD2 1 +ATOM 12219 N N . GLU D 2 404 ? -24.414 -38.840 -87.096 1.00 89.12 ? 404 GLU D N 1 +ATOM 12220 C CA . GLU D 2 404 ? -23.857 -37.855 -86.180 1.00 88.79 ? 404 GLU D CA 1 +ATOM 12221 C C . GLU D 2 404 ? -24.880 -37.385 -85.165 1.00 81.50 ? 404 GLU D C 1 +ATOM 12222 O O . GLU D 2 404 ? -24.514 -37.045 -84.034 1.00 83.84 ? 404 GLU D O 1 +ATOM 12223 C CB . GLU D 2 404 ? -23.320 -36.644 -86.948 1.00 97.23 ? 404 GLU D CB 1 +ATOM 12224 C CG . GLU D 2 404 ? -22.178 -35.919 -86.242 1.00 105.18 ? 404 GLU D CG 1 +ATOM 12225 C CD . GLU D 2 404 ? -21.614 -34.773 -87.066 1.00 118.48 ? 404 GLU D CD 1 +ATOM 12226 O OE1 . GLU D 2 404 ? -22.201 -33.668 -87.037 1.00 104.05 ? 404 GLU D OE1 1 +ATOM 12227 O OE2 . GLU D 2 404 ? -20.586 -34.978 -87.747 1.00 137.60 ? 404 GLU D OE2 1 +ATOM 12228 N N . VAL D 2 405 ? -26.162 -37.378 -85.535 1.00 75.09 ? 405 VAL D N 1 +ATOM 12229 C CA . VAL D 2 405 ? -27.181 -36.898 -84.609 1.00 75.75 ? 405 VAL D CA 1 +ATOM 12230 C C . VAL D 2 405 ? -27.587 -37.965 -83.611 1.00 77.46 ? 405 VAL D C 1 +ATOM 12231 O O . VAL D 2 405 ? -28.205 -37.638 -82.593 1.00 79.95 ? 405 VAL D O 1 +ATOM 12232 C CB . VAL D 2 405 ? -28.420 -36.389 -85.370 1.00 69.57 ? 405 VAL D CB 1 +ATOM 12233 C CG1 . VAL D 2 405 ? -29.381 -37.525 -85.666 1.00 71.62 ? 405 VAL D CG1 1 +ATOM 12234 C CG2 . VAL D 2 405 ? -29.111 -35.286 -84.590 1.00 67.84 ? 405 VAL D CG2 1 +ATOM 12235 N N . LYS D 2 406 ? -27.220 -39.223 -83.844 1.00 80.97 ? 406 LYS D N 1 +ATOM 12236 C CA . LYS D 2 406 ? -27.424 -40.265 -82.851 1.00 82.14 ? 406 LYS D CA 1 +ATOM 12237 C C . LYS D 2 406 ? -26.248 -40.366 -81.887 1.00 80.57 ? 406 LYS D C 1 +ATOM 12238 O O . LYS D 2 406 ? -26.166 -41.327 -81.114 1.00 75.20 ? 406 LYS D O 1 +ATOM 12239 C CB . LYS D 2 406 ? -27.694 -41.609 -83.536 1.00 77.27 ? 406 LYS D CB 1 +ATOM 12240 C CG . LYS D 2 406 ? -26.536 -42.163 -84.333 1.00 85.48 ? 406 LYS D CG 1 +ATOM 12241 C CD . LYS D 2 406 ? -26.897 -43.530 -84.904 1.00 97.79 ? 406 LYS D CD 1 +ATOM 12242 C CE . LYS D 2 406 ? -28.118 -43.444 -85.819 1.00 91.18 ? 406 LYS D CE 1 +ATOM 12243 N NZ . LYS D 2 406 ? -28.915 -44.709 -85.875 1.00 79.13 ? 406 LYS D NZ 1 +ATOM 12244 N N . GLN D 2 407 ? -25.355 -39.377 -81.907 1.00 81.73 ? 407 GLN D N 1 +ATOM 12245 C CA . GLN D 2 407 ? -24.262 -39.263 -80.956 1.00 82.18 ? 407 GLN D CA 1 +ATOM 12246 C C . GLN D 2 407 ? -24.466 -38.127 -79.964 1.00 82.94 ? 407 GLN D C 1 +ATOM 12247 O O . GLN D 2 407 ? -23.711 -38.036 -78.989 1.00 85.65 ? 407 GLN D O 1 +ATOM 12248 C CB . GLN D 2 407 ? -22.931 -39.046 -81.693 1.00 82.84 ? 407 GLN D CB 1 +ATOM 12249 C CG . GLN D 2 407 ? -21.773 -39.837 -81.125 1.00 82.30 ? 407 GLN D CG 1 +ATOM 12250 C CD . GLN D 2 407 ? -21.424 -41.028 -81.992 1.00 83.23 ? 407 GLN D CD 1 +ATOM 12251 O OE1 . GLN D 2 407 ? -21.557 -40.972 -83.212 1.00 73.28 ? 407 GLN D OE1 1 +ATOM 12252 N NE2 . GLN D 2 407 ? -20.982 -42.117 -81.365 1.00 85.78 ? 407 GLN D NE2 1 +ATOM 12253 N N . THR D 2 408 ? -25.446 -37.251 -80.202 1.00 76.92 ? 408 THR D N 1 +ATOM 12254 C CA . THR D 2 408 ? -25.748 -36.154 -79.296 1.00 78.81 ? 408 THR D CA 1 +ATOM 12255 C C . THR D 2 408 ? -26.245 -36.687 -77.952 1.00 77.29 ? 408 THR D C 1 +ATOM 12256 O O . THR D 2 408 ? -26.779 -37.797 -77.874 1.00 82.94 ? 408 THR D O 1 +ATOM 12257 C CB . THR D 2 408 ? -26.796 -35.242 -79.922 1.00 78.35 ? 408 THR D CB 1 +ATOM 12258 O OG1 . THR D 2 408 ? -27.522 -35.979 -80.912 1.00 79.56 ? 408 THR D OG1 1 +ATOM 12259 C CG2 . THR D 2 408 ? -26.129 -34.043 -80.571 1.00 77.99 ? 408 THR D CG2 1 +ATOM 12260 N N . PRO D 2 409 ? -26.126 -35.887 -76.892 1.00 74.36 ? 409 PRO D N 1 +ATOM 12261 C CA . PRO D 2 409 ? -26.460 -36.370 -75.535 1.00 82.51 ? 409 PRO D CA 1 +ATOM 12262 C C . PRO D 2 409 ? -27.882 -36.898 -75.403 1.00 89.50 ? 409 PRO D C 1 +ATOM 12263 O O . PRO D 2 409 ? -28.076 -37.947 -74.768 1.00 92.42 ? 409 PRO D O 1 +ATOM 12264 C CB . PRO D 2 409 ? -26.233 -35.133 -74.645 1.00 78.27 ? 409 PRO D CB 1 +ATOM 12265 C CG . PRO D 2 409 ? -25.989 -33.978 -75.589 1.00 79.58 ? 409 PRO D CG 1 +ATOM 12266 C CD . PRO D 2 409 ? -25.443 -34.582 -76.841 1.00 73.22 ? 409 PRO D CD 1 +ATOM 12267 N N . PRO D 2 410 ? -28.903 -36.242 -75.961 1.00 81.63 ? 410 PRO D N 1 +ATOM 12268 C CA . PRO D 2 410 ? -30.271 -36.741 -75.747 1.00 72.92 ? 410 PRO D CA 1 +ATOM 12269 C C . PRO D 2 410 ? -30.813 -37.633 -76.856 1.00 71.95 ? 410 PRO D C 1 +ATOM 12270 O O . PRO D 2 410 ? -31.941 -38.112 -76.718 1.00 72.89 ? 410 PRO D O 1 +ATOM 12271 C CB . PRO D 2 410 ? -31.076 -35.440 -75.670 1.00 65.78 ? 410 PRO D CB 1 +ATOM 12272 C CG . PRO D 2 410 ? -30.325 -34.482 -76.567 1.00 74.36 ? 410 PRO D CG 1 +ATOM 12273 C CD . PRO D 2 410 ? -28.950 -35.055 -76.835 1.00 70.72 ? 410 PRO D CD 1 +ATOM 12274 N N . TYR D 2 411 ? -30.056 -37.877 -77.926 1.00 72.67 ? 411 TYR D N 1 +ATOM 12275 C CA . TYR D 2 411 ? -30.539 -38.662 -79.054 1.00 70.28 ? 411 TYR D CA 1 +ATOM 12276 C C . TYR D 2 411 ? -29.892 -40.035 -79.130 1.00 69.77 ? 411 TYR D C 1 +ATOM 12277 O O . TYR D 2 411 ? -30.147 -40.776 -80.084 1.00 71.39 ? 411 TYR D O 1 +ATOM 12278 C CB . TYR D 2 411 ? -30.312 -37.921 -80.372 1.00 67.48 ? 411 TYR D CB 1 +ATOM 12279 C CG . TYR D 2 411 ? -31.176 -36.702 -80.597 1.00 58.79 ? 411 TYR D CG 1 +ATOM 12280 C CD1 . TYR D 2 411 ? -31.679 -35.965 -79.537 1.00 67.00 ? 411 TYR D CD1 1 +ATOM 12281 C CD2 . TYR D 2 411 ? -31.476 -36.282 -81.879 1.00 57.35 ? 411 TYR D CD2 1 +ATOM 12282 C CE1 . TYR D 2 411 ? -32.460 -34.849 -79.746 1.00 63.77 ? 411 TYR D CE1 1 +ATOM 12283 C CE2 . TYR D 2 411 ? -32.251 -35.171 -82.096 1.00 62.17 ? 411 TYR D CE2 1 +ATOM 12284 C CZ . TYR D 2 411 ? -32.742 -34.455 -81.030 1.00 58.84 ? 411 TYR D CZ 1 +ATOM 12285 O OH . TYR D 2 411 ? -33.519 -33.341 -81.254 1.00 54.71 ? 411 TYR D OH 1 +ATOM 12286 N N . ASP D 2 412 ? -29.071 -40.398 -78.154 1.00 73.16 ? 412 ASP D N 1 +ATOM 12287 C CA . ASP D 2 412 ? -28.546 -41.751 -78.049 1.00 74.43 ? 412 ASP D CA 1 +ATOM 12288 C C . ASP D 2 412 ? -29.133 -42.435 -76.821 1.00 71.79 ? 412 ASP D C 1 +ATOM 12289 O O . ASP D 2 412 ? -28.512 -43.309 -76.216 1.00 77.19 ? 412 ASP D O 1 +ATOM 12290 C CB . ASP D 2 412 ? -27.018 -41.741 -78.012 1.00 77.65 ? 412 ASP D CB 1 +ATOM 12291 C CG . ASP D 2 412 ? -26.462 -41.096 -76.752 1.00 82.67 ? 412 ASP D CG 1 +ATOM 12292 O OD1 . ASP D 2 412 ? -27.180 -40.289 -76.119 1.00 80.49 ? 412 ASP D OD1 1 +ATOM 12293 O OD2 . ASP D 2 412 ? -25.290 -41.367 -76.415 1.00 81.96 ? 412 ASP D OD2 1 +ATOM 12294 N N . ARG D 2 413 ? -30.351 -42.044 -76.470 1.00 66.80 ? 413 ARG D N 1 +ATOM 12295 C CA . ARG D 2 413 ? -31.106 -42.640 -75.378 1.00 74.49 ? 413 ARG D CA 1 +ATOM 12296 C C . ARG D 2 413 ? -32.568 -42.654 -75.813 1.00 75.39 ? 413 ARG D C 1 +ATOM 12297 O O . ARG D 2 413 ? -32.880 -42.640 -77.009 1.00 75.20 ? 413 ARG D O 1 +ATOM 12298 C CB . ARG D 2 413 ? -30.854 -41.874 -74.067 1.00 82.27 ? 413 ARG D CB 1 +ATOM 12299 C CG . ARG D 2 413 ? -30.213 -42.701 -72.960 1.00 89.07 ? 413 ARG D CG 1 +ATOM 12300 C CD . ARG D 2 413 ? -29.173 -41.893 -72.187 1.00 93.47 ? 413 ARG D CD 1 +ATOM 12301 N NE . ARG D 2 413 ? -28.522 -42.689 -71.145 1.00 116.74 ? 413 ARG D NE 1 +ATOM 12302 C CZ . ARG D 2 413 ? -27.393 -42.344 -70.529 1.00 106.28 ? 413 ARG D CZ 1 +ATOM 12303 N NH1 . ARG D 2 413 ? -26.777 -41.213 -70.853 1.00 101.08 ? 413 ARG D NH1 1 +ATOM 12304 N NH2 . ARG D 2 413 ? -26.877 -43.133 -69.593 1.00 91.80 ? 413 ARG D NH2 1 +ATOM 12305 N N . GLY D 2 414 ? -33.477 -42.683 -74.848 1.00 74.78 ? 414 GLY D N 1 +ATOM 12306 C CA . GLY D 2 414 ? -34.871 -42.770 -75.210 1.00 72.47 ? 414 GLY D CA 1 +ATOM 12307 C C . GLY D 2 414 ? -35.165 -44.084 -75.933 1.00 76.02 ? 414 GLY D C 1 +ATOM 12308 O O . GLY D 2 414 ? -34.351 -45.007 -75.922 1.00 75.00 ? 414 GLY D O 1 +ATOM 12309 N N . THR D 2 415 ? -36.339 -44.186 -76.582 1.00 78.67 ? 415 THR D N 1 +ATOM 12310 C CA . THR D 2 415 ? -37.511 -43.275 -76.696 1.00 75.47 ? 415 THR D CA 1 +ATOM 12311 C C . THR D 2 415 ? -37.266 -42.109 -77.668 1.00 76.08 ? 415 THR D C 1 +ATOM 12312 O O . THR D 2 415 ? -38.070 -41.892 -78.575 1.00 77.09 ? 415 THR D O 1 +ATOM 12313 C CB . THR D 2 415 ? -38.032 -42.723 -75.322 1.00 80.02 ? 415 THR D CB 1 +ATOM 12314 O OG1 . THR D 2 415 ? -37.898 -43.729 -74.310 1.00 79.72 ? 415 THR D OG1 1 +ATOM 12315 C CG2 . THR D 2 415 ? -39.504 -42.344 -75.420 1.00 61.59 ? 415 THR D CG2 1 +ATOM 12316 N N . ARG D 2 416 ? -36.182 -41.356 -77.500 1.00 75.87 ? 416 ARG D N 1 +ATOM 12317 C CA . ARG D 2 416 ? -35.857 -40.338 -78.488 1.00 75.66 ? 416 ARG D CA 1 +ATOM 12318 C C . ARG D 2 416 ? -35.398 -41.006 -79.785 1.00 79.92 ? 416 ARG D C 1 +ATOM 12319 O O . ARG D 2 416 ? -35.220 -42.227 -79.853 1.00 87.40 ? 416 ARG D O 1 +ATOM 12320 C CB . ARG D 2 416 ? -34.787 -39.388 -77.953 1.00 81.28 ? 416 ARG D CB 1 +ATOM 12321 C CG . ARG D 2 416 ? -34.824 -38.005 -78.591 1.00 76.49 ? 416 ARG D CG 1 +ATOM 12322 C CD . ARG D 2 416 ? -36.162 -37.315 -78.348 1.00 71.53 ? 416 ARG D CD 1 +ATOM 12323 N NE . ARG D 2 416 ? -36.089 -36.328 -77.272 1.00 61.66 ? 416 ARG D NE 1 +ATOM 12324 C CZ . ARG D 2 416 ? -36.494 -36.543 -76.024 1.00 67.47 ? 416 ARG D CZ 1 +ATOM 12325 N NH1 . ARG D 2 416 ? -37.010 -37.715 -75.680 1.00 68.72 ? 416 ARG D NH1 1 +ATOM 12326 N NH2 . ARG D 2 416 ? -36.385 -35.583 -75.116 1.00 64.89 ? 416 ARG D NH2 1 +ATOM 12327 N N . LEU D 2 417 ? -35.190 -40.186 -80.821 1.00 70.99 ? 417 LEU D N 1 +ATOM 12328 C CA . LEU D 2 417 ? -35.036 -40.654 -82.199 1.00 68.46 ? 417 LEU D CA 1 +ATOM 12329 C C . LEU D 2 417 ? -36.298 -41.355 -82.672 1.00 65.25 ? 417 LEU D C 1 +ATOM 12330 O O . LEU D 2 417 ? -36.887 -40.968 -83.685 1.00 63.97 ? 417 LEU D O 1 +ATOM 12331 C CB . LEU D 2 417 ? -33.839 -41.593 -82.363 1.00 65.87 ? 417 LEU D CB 1 +ATOM 12332 C CG . LEU D 2 417 ? -32.566 -40.987 -82.941 1.00 76.59 ? 417 LEU D CG 1 +ATOM 12333 C CD1 . LEU D 2 417 ? -31.452 -42.024 -82.967 1.00 86.82 ? 417 LEU D CD1 1 +ATOM 12334 C CD2 . LEU D 2 417 ? -32.849 -40.456 -84.337 1.00 58.83 ? 417 LEU D CD2 1 +ATOM 12335 N N . LEU D 2 418 ? -36.693 -42.411 -81.960 1.00 71.36 ? 418 LEU D N 1 +ATOM 12336 C CA . LEU D 2 418 ? -37.959 -43.077 -82.243 1.00 74.30 ? 418 LEU D CA 1 +ATOM 12337 C C . LEU D 2 418 ? -39.131 -42.107 -82.134 1.00 72.22 ? 418 LEU D C 1 +ATOM 12338 O O . LEU D 2 418 ? -40.033 -42.108 -82.981 1.00 71.21 ? 418 LEU D O 1 +ATOM 12339 C CB . LEU D 2 418 ? -38.152 -44.266 -81.298 1.00 78.32 ? 418 LEU D CB 1 +ATOM 12340 C CG . LEU D 2 418 ? -37.354 -45.559 -81.515 1.00 77.16 ? 418 LEU D CG 1 +ATOM 12341 C CD1 . LEU D 2 418 ? -37.827 -46.231 -82.787 1.00 65.24 ? 418 LEU D CD1 1 +ATOM 12342 C CD2 . LEU D 2 418 ? -35.828 -45.382 -81.512 1.00 73.05 ? 418 LEU D CD2 1 +ATOM 12343 N N . ASP D 2 419 ? -39.159 -41.299 -81.069 1.00 65.77 ? 419 ASP D N 1 +ATOM 12344 C CA . ASP D 2 419 ? -40.202 -40.286 -80.940 1.00 67.40 ? 419 ASP D CA 1 +ATOM 12345 C C . ASP D 2 419 ? -40.216 -39.345 -82.140 1.00 63.46 ? 419 ASP D C 1 +ATOM 12346 O O . ASP D 2 419 ? -41.280 -39.054 -82.698 1.00 61.62 ? 419 ASP D O 1 +ATOM 12347 C CB . ASP D 2 419 ? -40.031 -39.518 -79.632 1.00 71.54 ? 419 ASP D CB 1 +ATOM 12348 C CG . ASP D 2 419 ? -40.600 -40.273 -78.443 1.00 76.16 ? 419 ASP D CG 1 +ATOM 12349 O OD1 . ASP D 2 419 ? -41.498 -41.123 -78.646 1.00 65.29 ? 419 ASP D OD1 1 +ATOM 12350 O OD2 . ASP D 2 419 ? -40.146 -40.017 -77.311 1.00 83.04 ? 419 ASP D OD2 1 +ATOM 12351 N N . ILE D 2 420 ? -39.042 -38.857 -82.550 1.00 58.67 ? 420 ILE D N 1 +ATOM 12352 C CA . ILE D 2 420 ? -38.959 -38.036 -83.754 1.00 53.14 ? 420 ILE D CA 1 +ATOM 12353 C C . ILE D 2 420 ? -39.502 -38.800 -84.952 1.00 57.96 ? 420 ILE D C 1 +ATOM 12354 O O . ILE D 2 420 ? -40.205 -38.238 -85.800 1.00 59.06 ? 420 ILE D O 1 +ATOM 12355 C CB . ILE D 2 420 ? -37.505 -37.586 -83.987 1.00 48.28 ? 420 ILE D CB 1 +ATOM 12356 C CG1 . ILE D 2 420 ? -36.991 -36.838 -82.761 1.00 54.99 ? 420 ILE D CG1 1 +ATOM 12357 C CG2 . ILE D 2 420 ? -37.386 -36.744 -85.241 1.00 38.00 ? 420 ILE D CG2 1 +ATOM 12358 C CD1 . ILE D 2 420 ? -35.504 -36.660 -82.766 1.00 63.29 ? 420 ILE D CD1 1 +ATOM 12359 N N . MET D 2 421 ? -39.185 -40.095 -85.039 1.00 58.57 ? 421 MET D N 1 +ATOM 12360 C CA . MET D 2 421 ? -39.692 -40.909 -86.136 1.00 55.11 ? 421 MET D CA 1 +ATOM 12361 C C . MET D 2 421 ? -41.214 -40.949 -86.127 1.00 57.11 ? 421 MET D C 1 +ATOM 12362 O O . MET D 2 421 ? -41.857 -40.729 -87.162 1.00 51.90 ? 421 MET D O 1 +ATOM 12363 C CB . MET D 2 421 ? -39.109 -42.316 -86.061 1.00 53.62 ? 421 MET D CB 1 +ATOM 12364 C CG . MET D 2 421 ? -37.606 -42.366 -86.283 1.00 54.03 ? 421 MET D CG 1 +ATOM 12365 S SD . MET D 2 421 ? -37.020 -41.535 -87.775 1.00 46.94 ? 421 MET D SD 1 +ATOM 12366 C CE . MET D 2 421 ? -35.968 -40.286 -87.047 1.00 54.84 ? 421 MET D CE 1 +ATOM 12367 N N . ASP D 2 422 ? -41.812 -41.194 -84.955 1.00 56.27 ? 422 ASP D N 1 +ATOM 12368 C CA . ASP D 2 422 ? -43.268 -41.159 -84.858 1.00 58.30 ? 422 ASP D CA 1 +ATOM 12369 C C . ASP D 2 422 ? -43.814 -39.809 -85.301 1.00 56.69 ? 422 ASP D C 1 +ATOM 12370 O O . ASP D 2 422 ? -44.903 -39.734 -85.881 1.00 51.93 ? 422 ASP D O 1 +ATOM 12371 C CB . ASP D 2 422 ? -43.718 -41.464 -83.424 1.00 57.92 ? 422 ASP D CB 1 +ATOM 12372 C CG . ASP D 2 422 ? -43.432 -42.900 -83.000 1.00 61.78 ? 422 ASP D CG 1 +ATOM 12373 O OD1 . ASP D 2 422 ? -42.865 -43.669 -83.806 1.00 56.98 ? 422 ASP D OD1 1 +ATOM 12374 O OD2 . ASP D 2 422 ? -43.804 -43.266 -81.861 1.00 61.94 ? 422 ASP D OD2 1 +ATOM 12375 N N . MET D 2 423 ? -43.033 -38.749 -85.118 1.00 54.84 ? 423 MET D N 1 +ATOM 12376 C CA . MET D 2 423 ? -43.452 -37.411 -85.499 1.00 49.88 ? 423 MET D CA 1 +ATOM 12377 C C . MET D 2 423 ? -43.160 -37.123 -86.962 1.00 51.75 ? 423 MET D C 1 +ATOM 12378 O O . MET D 2 423 ? -44.012 -36.569 -87.662 1.00 54.91 ? 423 MET D O 1 +ATOM 12379 C CB . MET D 2 423 ? -42.760 -36.377 -84.605 1.00 47.08 ? 423 MET D CB 1 +ATOM 12380 C CG . MET D 2 423 ? -42.670 -34.980 -85.193 1.00 50.96 ? 423 MET D CG 1 +ATOM 12381 S SD . MET D 2 423 ? -41.624 -33.881 -84.207 1.00 46.11 ? 423 MET D SD 1 +ATOM 12382 C CE . MET D 2 423 ? -42.811 -33.267 -83.016 1.00 62.57 ? 423 MET D CE 1 +ATOM 12383 N N . THR D 2 424 ? -41.981 -37.505 -87.454 1.00 49.44 ? 424 THR D N 1 +ATOM 12384 C CA . THR D 2 424 ? -41.663 -37.193 -88.841 1.00 53.88 ? 424 THR D CA 1 +ATOM 12385 C C . THR D 2 424 ? -42.541 -37.987 -89.802 1.00 58.10 ? 424 THR D C 1 +ATOM 12386 O O . THR D 2 424 ? -42.839 -37.513 -90.905 1.00 54.57 ? 424 THR D O 1 +ATOM 12387 C CB . THR D 2 424 ? -40.175 -37.433 -89.113 1.00 54.11 ? 424 THR D CB 1 +ATOM 12388 O OG1 . THR D 2 424 ? -39.861 -37.043 -90.457 1.00 59.71 ? 424 THR D OG1 1 +ATOM 12389 C CG2 . THR D 2 424 ? -39.822 -38.888 -88.930 1.00 56.92 ? 424 THR D CG2 1 +ATOM 12390 N N . ILE D 2 425 ? -42.995 -39.173 -89.394 1.00 57.16 ? 425 ILE D N 1 +ATOM 12391 C CA . ILE D 2 425 ? -43.998 -39.876 -90.185 1.00 58.73 ? 425 ILE D CA 1 +ATOM 12392 C C . ILE D 2 425 ? -45.312 -39.106 -90.163 1.00 59.39 ? 425 ILE D C 1 +ATOM 12393 O O . ILE D 2 425 ? -45.988 -38.972 -91.191 1.00 53.20 ? 425 ILE D O 1 +ATOM 12394 C CB . ILE D 2 425 ? -44.171 -41.315 -89.669 1.00 56.02 ? 425 ILE D CB 1 +ATOM 12395 C CG1 . ILE D 2 425 ? -42.881 -42.109 -89.870 1.00 57.69 ? 425 ILE D CG1 1 +ATOM 12396 C CG2 . ILE D 2 425 ? -45.315 -42.006 -90.386 1.00 53.33 ? 425 ILE D CG2 1 +ATOM 12397 C CD1 . ILE D 2 425 ? -42.976 -43.533 -89.396 1.00 53.47 ? 425 ILE D CD1 1 +ATOM 12398 N N . PHE D 2 426 ? -45.679 -38.578 -88.989 1.00 59.06 ? 426 PHE D N 1 +ATOM 12399 C CA . PHE D 2 426 ? -46.869 -37.741 -88.848 1.00 56.03 ? 426 PHE D CA 1 +ATOM 12400 C C . PHE D 2 426 ? -46.804 -36.531 -89.780 1.00 57.07 ? 426 PHE D C 1 +ATOM 12401 O O . PHE D 2 426 ? -47.750 -36.258 -90.529 1.00 56.28 ? 426 PHE D O 1 +ATOM 12402 C CB . PHE D 2 426 ? -47.000 -37.312 -87.380 1.00 54.54 ? 426 PHE D CB 1 +ATOM 12403 C CG . PHE D 2 426 ? -48.307 -36.635 -87.022 1.00 55.29 ? 426 PHE D CG 1 +ATOM 12404 C CD1 . PHE D 2 426 ? -49.322 -36.467 -87.945 1.00 60.21 ? 426 PHE D CD1 1 +ATOM 12405 C CD2 . PHE D 2 426 ? -48.497 -36.141 -85.742 1.00 49.00 ? 426 PHE D CD2 1 +ATOM 12406 C CE1 . PHE D 2 426 ? -50.503 -35.833 -87.591 1.00 55.85 ? 426 PHE D CE1 1 +ATOM 12407 C CE2 . PHE D 2 426 ? -49.671 -35.508 -85.387 1.00 44.86 ? 426 PHE D CE2 1 +ATOM 12408 C CZ . PHE D 2 426 ? -50.674 -35.353 -86.311 1.00 45.69 ? 426 PHE D CZ 1 +ATOM 12409 N N . ASP D 2 427 ? -45.696 -35.786 -89.740 1.00 54.93 ? 427 ASP D N 1 +ATOM 12410 C CA . ASP D 2 427 ? -45.598 -34.565 -90.536 1.00 58.99 ? 427 ASP D CA 1 +ATOM 12411 C C . ASP D 2 427 ? -45.646 -34.847 -92.031 1.00 56.06 ? 427 ASP D C 1 +ATOM 12412 O O . ASP D 2 427 ? -46.157 -34.023 -92.800 1.00 51.51 ? 427 ASP D O 1 +ATOM 12413 C CB . ASP D 2 427 ? -44.318 -33.809 -90.189 1.00 61.40 ? 427 ASP D CB 1 +ATOM 12414 C CG . ASP D 2 427 ? -44.383 -33.155 -88.829 1.00 63.91 ? 427 ASP D CG 1 +ATOM 12415 O OD1 . ASP D 2 427 ? -45.500 -32.777 -88.408 1.00 61.62 ? 427 ASP D OD1 1 +ATOM 12416 O OD2 . ASP D 2 427 ? -43.320 -33.020 -88.185 1.00 58.48 ? 427 ASP D OD2 1 +ATOM 12417 N N . PHE D 2 428 ? -45.121 -35.993 -92.466 1.00 56.96 ? 428 PHE D N 1 +ATOM 12418 C CA . PHE D 2 428 ? -45.154 -36.305 -93.890 1.00 58.07 ? 428 PHE D CA 1 +ATOM 12419 C C . PHE D 2 428 ? -46.570 -36.618 -94.353 1.00 57.16 ? 428 PHE D C 1 +ATOM 12420 O O . PHE D 2 428 ? -46.974 -36.211 -95.449 1.00 56.33 ? 428 PHE D O 1 +ATOM 12421 C CB . PHE D 2 428 ? -44.227 -37.477 -94.200 1.00 53.30 ? 428 PHE D CB 1 +ATOM 12422 C CG . PHE D 2 428 ? -44.197 -37.854 -95.654 1.00 48.39 ? 428 PHE D CG 1 +ATOM 12423 C CD1 . PHE D 2 428 ? -43.499 -37.086 -96.567 1.00 55.62 ? 428 PHE D CD1 1 +ATOM 12424 C CD2 . PHE D 2 428 ? -44.870 -38.971 -96.106 1.00 49.85 ? 428 PHE D CD2 1 +ATOM 12425 C CE1 . PHE D 2 428 ? -43.472 -37.428 -97.905 1.00 59.97 ? 428 PHE D CE1 1 +ATOM 12426 C CE2 . PHE D 2 428 ? -44.848 -39.318 -97.440 1.00 55.44 ? 428 PHE D CE2 1 +ATOM 12427 C CZ . PHE D 2 428 ? -44.148 -38.545 -98.343 1.00 58.02 ? 428 PHE D CZ 1 +ATOM 12428 N N . LEU D 2 429 ? -47.342 -37.329 -93.528 1.00 52.21 ? 429 LEU D N 1 +ATOM 12429 C CA . LEU D 2 429 ? -48.721 -37.632 -93.889 1.00 51.96 ? 429 LEU D CA 1 +ATOM 12430 C C . LEU D 2 429 ? -49.538 -36.364 -94.096 1.00 54.29 ? 429 LEU D C 1 +ATOM 12431 O O . LEU D 2 429 ? -50.455 -36.346 -94.923 1.00 54.26 ? 429 LEU D O 1 +ATOM 12432 C CB . LEU D 2 429 ? -49.354 -38.508 -92.813 1.00 51.24 ? 429 LEU D CB 1 +ATOM 12433 C CG . LEU D 2 429 ? -48.661 -39.854 -92.612 1.00 46.13 ? 429 LEU D CG 1 +ATOM 12434 C CD1 . LEU D 2 429 ? -49.354 -40.646 -91.520 1.00 46.56 ? 429 LEU D CD1 1 +ATOM 12435 C CD2 . LEU D 2 429 ? -48.625 -40.633 -93.911 1.00 50.89 ? 429 LEU D CD2 1 +ATOM 12436 N N . MET D 2 430 ? -49.220 -35.296 -93.368 1.00 52.96 ? 430 MET D N 1 +ATOM 12437 C CA . MET D 2 430 ? -49.919 -34.030 -93.538 1.00 47.98 ? 430 MET D CA 1 +ATOM 12438 C C . MET D 2 430 ? -49.225 -33.099 -94.520 1.00 50.45 ? 430 MET D C 1 +ATOM 12439 O O . MET D 2 430 ? -49.883 -32.235 -95.115 1.00 48.61 ? 430 MET D O 1 +ATOM 12440 C CB . MET D 2 430 ? -50.062 -33.330 -92.189 1.00 45.21 ? 430 MET D CB 1 +ATOM 12441 C CG . MET D 2 430 ? -50.689 -34.189 -91.127 1.00 40.32 ? 430 MET D CG 1 +ATOM 12442 S SD . MET D 2 430 ? -51.081 -33.198 -89.681 1.00 52.72 ? 430 MET D SD 1 +ATOM 12443 C CE . MET D 2 430 ? -49.448 -32.648 -89.187 1.00 56.72 ? 430 MET D CE 1 +ATOM 12444 N N . GLY D 2 431 ? -47.916 -33.253 -94.707 1.00 50.37 ? 431 GLY D N 1 +ATOM 12445 C CA . GLY D 2 431 ? -47.157 -32.290 -95.479 1.00 57.01 ? 431 GLY D CA 1 +ATOM 12446 C C . GLY D 2 431 ? -46.687 -31.085 -94.699 1.00 57.32 ? 431 GLY D C 1 +ATOM 12447 O O . GLY D 2 431 ? -46.357 -30.057 -95.300 1.00 57.20 ? 431 GLY D O 1 +ATOM 12448 N N . ASN D 2 432 ? -46.636 -31.187 -93.373 1.00 53.85 ? 432 ASN D N 1 +ATOM 12449 C CA . ASN D 2 432 ? -46.271 -30.074 -92.499 1.00 52.31 ? 432 ASN D CA 1 +ATOM 12450 C C . ASN D 2 432 ? -44.751 -29.986 -92.423 1.00 56.96 ? 432 ASN D C 1 +ATOM 12451 O O . ASN D 2 432 ? -44.113 -30.689 -91.634 1.00 59.03 ? 432 ASN D O 1 +ATOM 12452 C CB . ASN D 2 432 ? -46.894 -30.277 -91.122 1.00 52.51 ? 432 ASN D CB 1 +ATOM 12453 C CG . ASN D 2 432 ? -46.398 -29.279 -90.094 1.00 56.86 ? 432 ASN D CG 1 +ATOM 12454 O OD1 . ASN D 2 432 ? -46.264 -28.088 -90.374 1.00 59.20 ? 432 ASN D OD1 1 +ATOM 12455 N ND2 . ASN D 2 432 ? -46.138 -29.763 -88.886 1.00 54.53 ? 432 ASN D ND2 1 +ATOM 12456 N N . MET D 2 433 ? -44.162 -29.101 -93.230 1.00 50.41 ? 433 MET D N 1 +ATOM 12457 C CA . MET D 2 433 ? -42.720 -28.893 -93.236 1.00 52.65 ? 433 MET D CA 1 +ATOM 12458 C C . MET D 2 433 ? -42.294 -27.740 -92.331 1.00 54.43 ? 433 MET D C 1 +ATOM 12459 O O . MET D 2 433 ? -41.196 -27.201 -92.498 1.00 53.97 ? 433 MET D O 1 +ATOM 12460 C CB . MET D 2 433 ? -42.220 -28.661 -94.668 1.00 52.89 ? 433 MET D CB 1 +ATOM 12461 C CG . MET D 2 433 ? -43.171 -27.861 -95.569 1.00 58.92 ? 433 MET D CG 1 +ATOM 12462 S SD . MET D 2 433 ? -42.598 -27.666 -97.287 1.00 57.64 ? 433 MET D SD 1 +ATOM 12463 C CE . MET D 2 433 ? -44.105 -27.122 -98.100 1.00 46.43 ? 433 MET D CE 1 +ATOM 12464 N N . ASP D 2 434 ? -43.133 -27.371 -91.362 1.00 57.98 ? 434 ASP D N 1 +ATOM 12465 C CA . ASP D 2 434 ? -42.862 -26.275 -90.440 1.00 57.59 ? 434 ASP D CA 1 +ATOM 12466 C C . ASP D 2 434 ? -42.568 -26.776 -89.028 1.00 61.24 ? 434 ASP D C 1 +ATOM 12467 O O . ASP D 2 434 ? -42.818 -26.073 -88.046 1.00 64.48 ? 434 ASP D O 1 +ATOM 12468 C CB . ASP D 2 434 ? -44.040 -25.302 -90.423 1.00 65.00 ? 434 ASP D CB 1 +ATOM 12469 C CG . ASP D 2 434 ? -43.660 -23.926 -89.909 1.00 72.26 ? 434 ASP D CG 1 +ATOM 12470 O OD1 . ASP D 2 434 ? -42.470 -23.559 -90.004 1.00 77.75 ? 434 ASP D OD1 1 +ATOM 12471 O OD2 . ASP D 2 434 ? -44.555 -23.213 -89.407 1.00 79.64 ? 434 ASP D OD2 1 +ATOM 12472 N N . ARG D 2 435 ? -42.047 -27.996 -88.911 1.00 57.64 ? 435 ARG D N 1 +ATOM 12473 C CA . ARG D 2 435 ? -41.752 -28.588 -87.608 1.00 50.76 ? 435 ARG D CA 1 +ATOM 12474 C C . ARG D 2 435 ? -40.306 -28.264 -87.237 1.00 57.08 ? 435 ARG D C 1 +ATOM 12475 O O . ARG D 2 435 ? -39.387 -29.069 -87.396 1.00 62.20 ? 435 ARG D O 1 +ATOM 12476 C CB . ARG D 2 435 ? -42.007 -30.087 -87.645 1.00 46.56 ? 435 ARG D CB 1 +ATOM 12477 C CG . ARG D 2 435 ? -41.861 -30.766 -86.310 1.00 48.01 ? 435 ARG D CG 1 +ATOM 12478 C CD . ARG D 2 435 ? -43.018 -30.444 -85.397 1.00 43.42 ? 435 ARG D CD 1 +ATOM 12479 N NE . ARG D 2 435 ? -44.261 -31.014 -85.894 1.00 38.04 ? 435 ARG D NE 1 +ATOM 12480 C CZ . ARG D 2 435 ? -45.425 -30.903 -85.269 1.00 43.23 ? 435 ARG D CZ 1 +ATOM 12481 N NH1 . ARG D 2 435 ? -45.498 -30.247 -84.122 1.00 46.35 ? 435 ARG D NH1 1 +ATOM 12482 N NH2 . ARG D 2 435 ? -46.513 -31.449 -85.787 1.00 51.99 ? 435 ARG D NH2 1 +ATOM 12483 N N . HIS D 2 436 ? -40.113 -27.070 -86.686 1.00 60.24 ? 436 HIS D N 1 +ATOM 12484 C CA . HIS D 2 436 ? -38.786 -26.621 -86.288 1.00 62.33 ? 436 HIS D CA 1 +ATOM 12485 C C . HIS D 2 436 ? -38.528 -26.761 -84.796 1.00 61.62 ? 436 HIS D C 1 +ATOM 12486 O O . HIS D 2 436 ? -37.389 -26.562 -84.360 1.00 60.96 ? 436 HIS D O 1 +ATOM 12487 C CB . HIS D 2 436 ? -38.578 -25.155 -86.701 1.00 67.05 ? 436 HIS D CB 1 +ATOM 12488 C CG . HIS D 2 436 ? -39.634 -24.214 -86.192 1.00 72.48 ? 436 HIS D CG 1 +ATOM 12489 N ND1 . HIS D 2 436 ? -40.628 -24.602 -85.319 1.00 73.82 ? 436 HIS D ND1 1 +ATOM 12490 C CD2 . HIS D 2 436 ? -39.847 -22.899 -86.437 1.00 79.32 ? 436 HIS D CD2 1 +ATOM 12491 C CE1 . HIS D 2 436 ? -41.407 -23.570 -85.048 1.00 76.34 ? 436 HIS D CE1 1 +ATOM 12492 N NE2 . HIS D 2 436 ? -40.955 -22.524 -85.716 1.00 89.12 ? 436 HIS D NE2 1 +ATOM 12493 N N . HIS D 2 437 ? -39.541 -27.121 -84.015 1.00 60.28 ? 437 HIS D N 1 +ATOM 12494 C CA . HIS D 2 437 ? -39.431 -27.187 -82.568 1.00 52.78 ? 437 HIS D CA 1 +ATOM 12495 C C . HIS D 2 437 ? -40.417 -28.232 -82.067 1.00 45.04 ? 437 HIS D C 1 +ATOM 12496 O O . HIS D 2 437 ? -41.537 -28.329 -82.577 1.00 43.60 ? 437 HIS D O 1 +ATOM 12497 C CB . HIS D 2 437 ? -39.744 -25.828 -81.920 1.00 63.66 ? 437 HIS D CB 1 +ATOM 12498 C CG . HIS D 2 437 ? -38.702 -24.773 -82.147 1.00 65.40 ? 437 HIS D CG 1 +ATOM 12499 N ND1 . HIS D 2 437 ? -37.380 -25.065 -82.411 1.00 65.76 ? 437 HIS D ND1 1 +ATOM 12500 C CD2 . HIS D 2 437 ? -38.786 -23.421 -82.115 1.00 61.63 ? 437 HIS D CD2 1 +ATOM 12501 C CE1 . HIS D 2 437 ? -36.700 -23.940 -82.546 1.00 59.69 ? 437 HIS D CE1 1 +ATOM 12502 N NE2 . HIS D 2 437 ? -37.530 -22.927 -82.370 1.00 57.00 ? 437 HIS D NE2 1 +ATOM 12503 N N . TYR D 2 438 ? -40.027 -28.968 -81.032 1.00 41.59 ? 438 TYR D N 1 +ATOM 12504 C CA . TYR D 2 438 ? -40.918 -29.955 -80.431 1.00 50.67 ? 438 TYR D CA 1 +ATOM 12505 C C . TYR D 2 438 ? -40.826 -29.828 -78.921 1.00 50.73 ? 438 TYR D C 1 +ATOM 12506 O O . TYR D 2 438 ? -39.732 -29.904 -78.355 1.00 53.24 ? 438 TYR D O 1 +ATOM 12507 C CB . TYR D 2 438 ? -40.597 -31.389 -80.885 1.00 52.53 ? 438 TYR D CB 1 +ATOM 12508 C CG . TYR D 2 438 ? -39.197 -31.888 -80.583 1.00 55.79 ? 438 TYR D CG 1 +ATOM 12509 C CD1 . TYR D 2 438 ? -38.138 -31.599 -81.430 1.00 57.14 ? 438 TYR D CD1 1 +ATOM 12510 C CD2 . TYR D 2 438 ? -38.943 -32.671 -79.463 1.00 53.85 ? 438 TYR D CD2 1 +ATOM 12511 C CE1 . TYR D 2 438 ? -36.862 -32.062 -81.160 1.00 57.10 ? 438 TYR D CE1 1 +ATOM 12512 C CE2 . TYR D 2 438 ? -37.674 -33.137 -79.184 1.00 51.43 ? 438 TYR D CE2 1 +ATOM 12513 C CZ . TYR D 2 438 ? -36.639 -32.832 -80.036 1.00 55.76 ? 438 TYR D CZ 1 +ATOM 12514 O OH . TYR D 2 438 ? -35.373 -33.294 -79.760 1.00 59.50 ? 438 TYR D OH 1 +ATOM 12515 N N . GLU D 2 439 ? -41.961 -29.559 -78.285 1.00 45.55 ? 439 GLU D N 1 +ATOM 12516 C CA . GLU D 2 439 ? -41.965 -29.362 -76.849 1.00 49.23 ? 439 GLU D CA 1 +ATOM 12517 C C . GLU D 2 439 ? -42.048 -30.705 -76.120 1.00 46.47 ? 439 GLU D C 1 +ATOM 12518 O O . GLU D 2 439 ? -42.382 -31.741 -76.697 1.00 46.26 ? 439 GLU D O 1 +ATOM 12519 C CB . GLU D 2 439 ? -43.117 -28.440 -76.443 1.00 62.15 ? 439 GLU D CB 1 +ATOM 12520 C CG . GLU D 2 439 ? -42.964 -26.980 -76.900 1.00 58.29 ? 439 GLU D CG 1 +ATOM 12521 C CD . GLU D 2 439 ? -44.100 -26.095 -76.392 1.00 60.76 ? 439 GLU D CD 1 +ATOM 12522 O OE1 . GLU D 2 439 ? -44.381 -26.130 -75.171 1.00 51.08 ? 439 GLU D OE1 1 +ATOM 12523 O OE2 . GLU D 2 439 ? -44.707 -25.361 -77.204 1.00 60.36 ? 439 GLU D OE2 1 +ATOM 12524 N N . THR D 2 440 ? -41.785 -30.656 -74.813 1.00 52.12 ? 440 THR D N 1 +ATOM 12525 C CA . THR D 2 440 ? -41.811 -31.821 -73.934 1.00 45.67 ? 440 THR D CA 1 +ATOM 12526 C C . THR D 2 440 ? -42.534 -31.446 -72.645 1.00 48.52 ? 440 THR D C 1 +ATOM 12527 O O . THR D 2 440 ? -43.504 -30.686 -72.684 1.00 56.07 ? 440 THR D O 1 +ATOM 12528 C CB . THR D 2 440 ? -40.392 -32.305 -73.635 1.00 44.97 ? 440 THR D CB 1 +ATOM 12529 O OG1 . THR D 2 440 ? -39.554 -32.039 -74.762 1.00 44.16 ? 440 THR D OG1 1 +ATOM 12530 C CG2 . THR D 2 440 ? -40.386 -33.793 -73.381 1.00 57.58 ? 440 THR D CG2 1 +ATOM 12531 N N . PHE D 2 441 ? -42.096 -31.961 -71.496 1.00 44.82 ? 441 PHE D N 1 +ATOM 12532 C CA . PHE D 2 441 ? -42.790 -31.628 -70.257 1.00 49.17 ? 441 PHE D CA 1 +ATOM 12533 C C . PHE D 2 441 ? -41.847 -31.433 -69.076 1.00 54.81 ? 441 PHE D C 1 +ATOM 12534 O O . PHE D 2 441 ? -42.326 -31.293 -67.943 1.00 58.67 ? 441 PHE D O 1 +ATOM 12535 C CB . PHE D 2 441 ? -43.850 -32.687 -69.914 1.00 44.00 ? 441 PHE D CB 1 +ATOM 12536 C CG . PHE D 2 441 ? -45.223 -32.362 -70.442 1.00 38.00 ? 441 PHE D CG 1 +ATOM 12537 C CD1 . PHE D 2 441 ? -46.039 -31.453 -69.795 1.00 38.00 ? 441 PHE D CD1 1 +ATOM 12538 C CD2 . PHE D 2 441 ? -45.684 -32.949 -71.605 1.00 41.07 ? 441 PHE D CD2 1 +ATOM 12539 C CE1 . PHE D 2 441 ? -47.300 -31.152 -70.292 1.00 41.74 ? 441 PHE D CE1 1 +ATOM 12540 C CE2 . PHE D 2 441 ? -46.941 -32.650 -72.104 1.00 39.61 ? 441 PHE D CE2 1 +ATOM 12541 C CZ . PHE D 2 441 ? -47.750 -31.752 -71.447 1.00 38.00 ? 441 PHE D CZ 1 +ATOM 12542 N N . GLU D 2 442 ? -40.531 -31.420 -69.296 1.00 51.13 ? 442 GLU D N 1 +ATOM 12543 C CA . GLU D 2 442 ? -39.571 -30.978 -68.287 1.00 57.33 ? 442 GLU D CA 1 +ATOM 12544 C C . GLU D 2 442 ? -39.632 -31.806 -67.008 1.00 62.29 ? 442 GLU D C 1 +ATOM 12545 O O . GLU D 2 442 ? -38.656 -32.478 -66.656 1.00 64.99 ? 442 GLU D O 1 +ATOM 12546 C CB . GLU D 2 442 ? -39.780 -29.497 -67.953 1.00 63.59 ? 442 GLU D CB 1 +ATOM 12547 C CG . GLU D 2 442 ? -38.650 -28.586 -68.411 1.00 70.57 ? 442 GLU D CG 1 +ATOM 12548 C CD . GLU D 2 442 ? -37.398 -28.703 -67.552 1.00 84.74 ? 442 GLU D CD 1 +ATOM 12549 O OE1 . GLU D 2 442 ? -36.281 -28.606 -68.103 1.00 72.72 ? 442 GLU D OE1 1 +ATOM 12550 O OE2 . GLU D 2 442 ? -37.536 -28.914 -66.323 1.00 94.74 ? 442 GLU D OE2 1 +ATOM 12551 N N . LYS D 2 443 ? -40.767 -31.764 -66.300 1.00 64.88 ? 443 LYS D N 1 +ATOM 12552 C CA . LYS D 2 443 ? -40.895 -32.467 -65.025 1.00 73.77 ? 443 LYS D CA 1 +ATOM 12553 C C . LYS D 2 443 ? -40.727 -33.971 -65.170 1.00 76.99 ? 443 LYS D C 1 +ATOM 12554 O O . LYS D 2 443 ? -40.612 -34.671 -64.157 1.00 85.15 ? 443 LYS D O 1 +ATOM 12555 C CB . LYS D 2 443 ? -42.258 -32.160 -64.380 1.00 80.06 ? 443 LYS D CB 1 +ATOM 12556 C CG . LYS D 2 443 ? -42.351 -32.511 -62.887 1.00 99.04 ? 443 LYS D CG 1 +ATOM 12557 C CD . LYS D 2 443 ? -43.690 -32.104 -62.280 1.00 99.70 ? 443 LYS D CD 1 +ATOM 12558 C CE . LYS D 2 443 ? -43.774 -32.450 -60.793 1.00 98.33 ? 443 LYS D CE 1 +ATOM 12559 N NZ . LYS D 2 443 ? -45.099 -32.089 -60.203 1.00 87.79 ? 443 LYS D NZ 1 +ATOM 12560 N N . PHE D 2 444 ? -40.661 -34.471 -66.400 1.00 72.28 ? 444 PHE D N 1 +ATOM 12561 C CA . PHE D 2 444 ? -40.524 -35.889 -66.693 1.00 65.02 ? 444 PHE D CA 1 +ATOM 12562 C C . PHE D 2 444 ? -39.089 -36.310 -66.976 1.00 65.46 ? 444 PHE D C 1 +ATOM 12563 O O . PHE D 2 444 ? -38.654 -37.370 -66.516 1.00 71.17 ? 444 PHE D O 1 +ATOM 12564 C CB . PHE D 2 444 ? -41.397 -36.244 -67.895 1.00 51.64 ? 444 PHE D CB 1 +ATOM 12565 C CG . PHE D 2 444 ? -42.864 -36.296 -67.587 1.00 53.13 ? 444 PHE D CG 1 +ATOM 12566 C CD1 . PHE D 2 444 ? -43.308 -36.723 -66.349 1.00 60.41 ? 444 PHE D CD1 1 +ATOM 12567 C CD2 . PHE D 2 444 ? -43.801 -35.917 -68.533 1.00 52.09 ? 444 PHE D CD2 1 +ATOM 12568 C CE1 . PHE D 2 444 ? -44.653 -36.774 -66.061 1.00 62.94 ? 444 PHE D CE1 1 +ATOM 12569 C CE2 . PHE D 2 444 ? -45.148 -35.968 -68.252 1.00 52.87 ? 444 PHE D CE2 1 +ATOM 12570 C CZ . PHE D 2 444 ? -45.575 -36.397 -67.014 1.00 59.68 ? 444 PHE D CZ 1 +ATOM 12571 N N . GLY D 2 445 ? -38.341 -35.498 -67.699 1.00 57.57 ? 445 GLY D N 1 +ATOM 12572 C CA . GLY D 2 445 ? -37.014 -35.847 -68.137 1.00 52.93 ? 445 GLY D CA 1 +ATOM 12573 C C . GLY D 2 445 ? -36.981 -36.149 -69.620 1.00 58.38 ? 445 GLY D C 1 +ATOM 12574 O O . GLY D 2 445 ? -37.903 -35.833 -70.374 1.00 60.80 ? 445 GLY D O 1 +ATOM 12575 N N . ASN D 2 446 ? -35.904 -36.813 -70.034 1.00 66.40 ? 446 ASN D N 1 +ATOM 12576 C CA . ASN D 2 446 ? -35.659 -37.104 -71.441 1.00 69.64 ? 446 ASN D CA 1 +ATOM 12577 C C . ASN D 2 446 ? -36.334 -38.397 -71.907 1.00 73.60 ? 446 ASN D C 1 +ATOM 12578 O O . ASN D 2 446 ? -35.955 -38.946 -72.949 1.00 67.05 ? 446 ASN D O 1 +ATOM 12579 C CB . ASN D 2 446 ? -34.146 -37.167 -71.695 1.00 64.39 ? 446 ASN D CB 1 +ATOM 12580 C CG . ASN D 2 446 ? -33.476 -35.795 -71.638 1.00 56.89 ? 446 ASN D CG 1 +ATOM 12581 O OD1 . ASN D 2 446 ? -34.019 -34.811 -72.125 1.00 60.83 ? 446 ASN D OD1 1 +ATOM 12582 N ND2 . ASN D 2 446 ? -32.292 -35.731 -71.036 1.00 49.70 ? 446 ASN D ND2 1 +ATOM 12583 N N . ASP D 2 447 ? -37.346 -38.870 -71.177 1.00 74.53 ? 447 ASP D N 1 +ATOM 12584 C CA . ASP D 2 447 ? -37.992 -40.157 -71.410 1.00 69.19 ? 447 ASP D CA 1 +ATOM 12585 C C . ASP D 2 447 ? -39.491 -40.007 -71.610 1.00 65.80 ? 447 ASP D C 1 +ATOM 12586 O O . ASP D 2 447 ? -40.283 -40.738 -71.014 1.00 71.54 ? 447 ASP D O 1 +ATOM 12587 C CB . ASP D 2 447 ? -37.743 -41.131 -70.259 1.00 76.63 ? 447 ASP D CB 1 +ATOM 12588 C CG . ASP D 2 447 ? -36.272 -41.373 -69.993 1.00 89.34 ? 447 ASP D CG 1 +ATOM 12589 O OD1 . ASP D 2 447 ? -35.480 -41.425 -70.964 1.00 86.23 ? 447 ASP D OD1 1 +ATOM 12590 O OD2 . ASP D 2 447 ? -35.914 -41.516 -68.804 1.00 89.11 ? 447 ASP D OD2 1 +ATOM 12591 N N . THR D 2 448 ? -39.913 -39.042 -72.421 1.00 57.87 ? 448 THR D N 1 +ATOM 12592 C CA . THR D 2 448 ? -41.334 -38.841 -72.654 1.00 62.85 ? 448 THR D CA 1 +ATOM 12593 C C . THR D 2 448 ? -41.597 -38.570 -74.119 1.00 59.24 ? 448 THR D C 1 +ATOM 12594 O O . THR D 2 448 ? -40.679 -38.478 -74.939 1.00 59.99 ? 448 THR D O 1 +ATOM 12595 C CB . THR D 2 448 ? -41.899 -37.698 -71.821 1.00 59.65 ? 448 THR D CB 1 +ATOM 12596 O OG1 . THR D 2 448 ? -40.917 -36.661 -71.711 1.00 69.53 ? 448 THR D OG1 1 +ATOM 12597 C CG2 . THR D 2 448 ? -42.291 -38.202 -70.476 1.00 66.32 ? 448 THR D CG2 1 +ATOM 12598 N N . PHE D 2 449 ? -42.879 -38.435 -74.430 1.00 54.05 ? 449 PHE D N 1 +ATOM 12599 C CA . PHE D 2 449 ? -43.310 -38.180 -75.789 1.00 56.52 ? 449 PHE D CA 1 +ATOM 12600 C C . PHE D 2 449 ? -43.090 -36.717 -76.138 1.00 49.24 ? 449 PHE D C 1 +ATOM 12601 O O . PHE D 2 449 ? -42.690 -35.898 -75.307 1.00 51.93 ? 449 PHE D O 1 +ATOM 12602 C CB . PHE D 2 449 ? -44.773 -38.566 -75.954 1.00 58.26 ? 449 PHE D CB 1 +ATOM 12603 C CG . PHE D 2 449 ? -45.720 -37.642 -75.259 1.00 48.36 ? 449 PHE D CG 1 +ATOM 12604 C CD1 . PHE D 2 449 ? -45.848 -37.670 -73.884 1.00 45.35 ? 449 PHE D CD1 1 +ATOM 12605 C CD2 . PHE D 2 449 ? -46.511 -36.772 -75.984 1.00 52.12 ? 449 PHE D CD2 1 +ATOM 12606 C CE1 . PHE D 2 449 ? -46.730 -36.838 -73.245 1.00 48.03 ? 449 PHE D CE1 1 +ATOM 12607 C CE2 . PHE D 2 449 ? -47.398 -35.937 -75.347 1.00 52.77 ? 449 PHE D CE2 1 +ATOM 12608 C CZ . PHE D 2 449 ? -47.508 -35.971 -73.976 1.00 46.16 ? 449 PHE D CZ 1 +ATOM 12609 N N . ILE D 2 450 ? -43.397 -36.386 -77.382 1.00 45.25 ? 450 ILE D N 1 +ATOM 12610 C CA . ILE D 2 450 ? -43.263 -35.036 -77.898 1.00 46.72 ? 450 ILE D CA 1 +ATOM 12611 C C . ILE D 2 450 ? -44.650 -34.541 -78.269 1.00 47.03 ? 450 ILE D C 1 +ATOM 12612 O O . ILE D 2 450 ? -45.413 -35.246 -78.937 1.00 51.45 ? 450 ILE D O 1 +ATOM 12613 C CB . ILE D 2 450 ? -42.292 -34.984 -79.089 1.00 41.89 ? 450 ILE D CB 1 +ATOM 12614 C CG1 . ILE D 2 450 ? -42.666 -36.022 -80.141 1.00 51.48 ? 450 ILE D CG1 1 +ATOM 12615 C CG2 . ILE D 2 450 ? -40.885 -35.280 -78.625 1.00 42.19 ? 450 ILE D CG2 1 +ATOM 12616 C CD1 . ILE D 2 450 ? -41.616 -36.174 -81.204 1.00 62.33 ? 450 ILE D CD1 1 +ATOM 12617 N N . ILE D 2 451 ? -45.005 -33.369 -77.764 1.00 47.29 ? 451 ILE D N 1 +ATOM 12618 C CA . ILE D 2 451 ? -46.307 -32.780 -78.042 1.00 46.11 ? 451 ILE D CA 1 +ATOM 12619 C C . ILE D 2 451 ? -46.274 -32.229 -79.460 1.00 48.16 ? 451 ILE D C 1 +ATOM 12620 O O . ILE D 2 451 ? -45.402 -31.426 -79.808 1.00 50.45 ? 451 ILE D O 1 +ATOM 12621 C CB . ILE D 2 451 ? -46.661 -31.685 -77.025 1.00 42.72 ? 451 ILE D CB 1 +ATOM 12622 C CG1 . ILE D 2 451 ? -46.472 -32.199 -75.607 1.00 40.46 ? 451 ILE D CG1 1 +ATOM 12623 C CG2 . ILE D 2 451 ? -48.103 -31.271 -77.180 1.00 47.25 ? 451 ILE D CG2 1 +ATOM 12624 C CD1 . ILE D 2 451 ? -45.157 -31.828 -75.017 1.00 38.00 ? 451 ILE D CD1 1 +ATOM 12625 N N . HIS D 2 452 ? -47.189 -32.703 -80.294 1.00 44.88 ? 452 HIS D N 1 +ATOM 12626 C CA . HIS D 2 452 ? -47.282 -32.259 -81.680 1.00 48.24 ? 452 HIS D CA 1 +ATOM 12627 C C . HIS D 2 452 ? -48.168 -31.012 -81.697 1.00 47.38 ? 452 HIS D C 1 +ATOM 12628 O O . HIS D 2 452 ? -49.397 -31.094 -81.683 1.00 46.89 ? 452 HIS D O 1 +ATOM 12629 C CB . HIS D 2 452 ? -47.814 -33.394 -82.552 1.00 52.36 ? 452 HIS D CB 1 +ATOM 12630 C CG . HIS D 2 452 ? -46.982 -34.649 -82.506 1.00 51.93 ? 452 HIS D CG 1 +ATOM 12631 N ND1 . HIS D 2 452 ? -47.485 -35.886 -82.853 1.00 49.26 ? 452 HIS D ND1 1 +ATOM 12632 C CD2 . HIS D 2 452 ? -45.678 -34.853 -82.196 1.00 49.80 ? 452 HIS D CD2 1 +ATOM 12633 C CE1 . HIS D 2 452 ? -46.535 -36.797 -82.741 1.00 46.22 ? 452 HIS D CE1 1 +ATOM 12634 N NE2 . HIS D 2 452 ? -45.427 -36.197 -82.347 1.00 42.29 ? 452 HIS D NE2 1 +ATOM 12635 N N . LEU D 2 453 ? -47.532 -29.839 -81.669 1.00 48.13 ? 453 LEU D N 1 +ATOM 12636 C CA . LEU D 2 453 ? -48.199 -28.542 -81.638 1.00 45.85 ? 453 LEU D CA 1 +ATOM 12637 C C . LEU D 2 453 ? -47.964 -27.779 -82.938 1.00 53.86 ? 453 LEU D C 1 +ATOM 12638 O O . LEU D 2 453 ? -47.084 -28.119 -83.731 1.00 58.09 ? 453 LEU D O 1 +ATOM 12639 C CB . LEU D 2 453 ? -47.699 -27.712 -80.456 1.00 40.25 ? 453 LEU D CB 1 +ATOM 12640 C CG . LEU D 2 453 ? -48.080 -28.299 -79.106 1.00 38.80 ? 453 LEU D CG 1 +ATOM 12641 C CD1 . LEU D 2 453 ? -47.420 -27.521 -77.982 1.00 51.02 ? 453 LEU D CD1 1 +ATOM 12642 C CD2 . LEU D 2 453 ? -49.582 -28.303 -78.959 1.00 38.00 ? 453 LEU D CD2 1 +ATOM 12643 N N . ASP D 2 454 ? -48.761 -26.726 -83.140 1.00 53.90 ? 454 ASP D N 1 +ATOM 12644 C CA . ASP D 2 454 ? -48.677 -25.853 -84.318 1.00 63.17 ? 454 ASP D CA 1 +ATOM 12645 C C . ASP D 2 454 ? -48.726 -26.664 -85.616 1.00 62.57 ? 454 ASP D C 1 +ATOM 12646 O O . ASP D 2 454 ? -47.798 -26.652 -86.430 1.00 61.66 ? 454 ASP D O 1 +ATOM 12647 C CB . ASP D 2 454 ? -47.410 -24.988 -84.277 1.00 71.04 ? 454 ASP D CB 1 +ATOM 12648 C CG . ASP D 2 454 ? -47.462 -23.912 -83.206 1.00 61.70 ? 454 ASP D CG 1 +ATOM 12649 O OD1 . ASP D 2 454 ? -47.313 -24.271 -82.021 1.00 49.46 ? 454 ASP D OD1 1 +ATOM 12650 O OD2 . ASP D 2 454 ? -47.613 -22.713 -83.550 1.00 59.25 ? 454 ASP D OD2 1 +ATOM 12651 N N . ASN D 2 455 ? -49.833 -27.378 -85.799 1.00 59.56 ? 455 ASN D N 1 +ATOM 12652 C CA . ASN D 2 455 ? -50.022 -28.250 -86.951 1.00 56.15 ? 455 ASN D CA 1 +ATOM 12653 C C . ASN D 2 455 ? -50.753 -27.573 -88.103 1.00 51.36 ? 455 ASN D C 1 +ATOM 12654 O O . ASN D 2 455 ? -51.134 -28.250 -89.063 1.00 47.08 ? 455 ASN D O 1 +ATOM 12655 C CB . ASN D 2 455 ? -50.786 -29.501 -86.525 1.00 51.42 ? 455 ASN D CB 1 +ATOM 12656 C CG . ASN D 2 455 ? -50.249 -30.089 -85.247 1.00 50.37 ? 455 ASN D CG 1 +ATOM 12657 O OD1 . ASN D 2 455 ? -49.039 -30.216 -85.074 1.00 48.94 ? 455 ASN D OD1 1 +ATOM 12658 N ND2 . ASN D 2 455 ? -51.146 -30.431 -84.329 1.00 49.41 ? 455 ASN D ND2 1 +ATOM 12659 N N . GLY D 2 456 ? -50.949 -26.258 -88.037 1.00 50.91 ? 456 GLY D N 1 +ATOM 12660 C CA . GLY D 2 456 ? -51.798 -25.569 -88.991 1.00 51.75 ? 456 GLY D CA 1 +ATOM 12661 C C . GLY D 2 456 ? -51.235 -25.447 -90.393 1.00 52.71 ? 456 GLY D C 1 +ATOM 12662 O O . GLY D 2 456 ? -51.965 -25.007 -91.289 1.00 49.48 ? 456 GLY D O 1 +ATOM 12663 N N . ARG D 2 457 ? -49.973 -25.814 -90.607 1.00 53.77 ? 457 ARG D N 1 +ATOM 12664 C CA . ARG D 2 457 ? -49.331 -25.655 -91.906 1.00 51.15 ? 457 ARG D CA 1 +ATOM 12665 C C . ARG D 2 457 ? -49.471 -26.878 -92.803 1.00 48.31 ? 457 ARG D C 1 +ATOM 12666 O O . ARG D 2 457 ? -49.010 -26.843 -93.949 1.00 45.62 ? 457 ARG D O 1 +ATOM 12667 C CB . ARG D 2 457 ? -47.842 -25.330 -91.723 1.00 54.88 ? 457 ARG D CB 1 +ATOM 12668 C CG . ARG D 2 457 ? -47.557 -24.149 -90.806 1.00 52.66 ? 457 ARG D CG 1 +ATOM 12669 C CD . ARG D 2 457 ? -47.022 -22.960 -91.590 1.00 54.77 ? 457 ARG D CD 1 +ATOM 12670 N NE . ARG D 2 457 ? -46.815 -21.787 -90.744 1.00 58.79 ? 457 ARG D NE 1 +ATOM 12671 C CZ . ARG D 2 457 ? -46.246 -20.656 -91.154 1.00 66.24 ? 457 ARG D CZ 1 +ATOM 12672 N NH1 . ARG D 2 457 ? -45.817 -20.537 -92.404 1.00 62.51 ? 457 ARG D NH1 1 +ATOM 12673 N NH2 . ARG D 2 457 ? -46.106 -19.639 -90.314 1.00 70.93 ? 457 ARG D NH2 1 +ATOM 12674 N N . GLY D 2 458 ? -50.108 -27.943 -92.322 1.00 47.29 ? 458 GLY D N 1 +ATOM 12675 C CA . GLY D 2 458 ? -50.323 -29.127 -93.122 1.00 49.02 ? 458 GLY D CA 1 +ATOM 12676 C C . GLY D 2 458 ? -51.544 -29.015 -94.015 1.00 53.68 ? 458 GLY D C 1 +ATOM 12677 O O . GLY D 2 458 ? -52.269 -28.020 -94.014 1.00 55.05 ? 458 GLY D O 1 +ATOM 12678 N N . PHE D 2 459 ? -51.748 -30.061 -94.817 1.00 54.85 ? 459 PHE D N 1 +ATOM 12679 C CA . PHE D 2 459 ? -52.900 -30.169 -95.709 1.00 51.75 ? 459 PHE D CA 1 +ATOM 12680 C C . PHE D 2 459 ? -53.001 -28.947 -96.614 1.00 53.35 ? 459 PHE D C 1 +ATOM 12681 O O . PHE D 2 459 ? -54.067 -28.358 -96.800 1.00 51.58 ? 459 PHE D O 1 +ATOM 12682 C CB . PHE D 2 459 ? -54.192 -30.386 -94.922 1.00 43.01 ? 459 PHE D CB 1 +ATOM 12683 C CG . PHE D 2 459 ? -54.193 -31.648 -94.119 1.00 41.47 ? 459 PHE D CG 1 +ATOM 12684 C CD1 . PHE D 2 459 ? -54.570 -32.845 -94.698 1.00 46.10 ? 459 PHE D CD1 1 +ATOM 12685 C CD2 . PHE D 2 459 ? -53.804 -31.646 -92.796 1.00 44.74 ? 459 PHE D CD2 1 +ATOM 12686 C CE1 . PHE D 2 459 ? -54.560 -34.013 -93.974 1.00 41.71 ? 459 PHE D CE1 1 +ATOM 12687 C CE2 . PHE D 2 459 ? -53.794 -32.815 -92.066 1.00 47.55 ? 459 PHE D CE2 1 +ATOM 12688 C CZ . PHE D 2 459 ? -54.173 -33.999 -92.657 1.00 41.63 ? 459 PHE D CZ 1 +ATOM 12689 N N . GLY D 2 460 ? -51.857 -28.561 -97.172 1.00 53.96 ? 460 GLY D N 1 +ATOM 12690 C CA . GLY D 2 460 ? -51.806 -27.433 -98.078 1.00 61.63 ? 460 GLY D CA 1 +ATOM 12691 C C . GLY D 2 460 ? -51.665 -27.821 -99.535 1.00 59.37 ? 460 GLY D C 1 +ATOM 12692 O O . GLY D 2 460 ? -51.995 -27.033 -100.427 1.00 59.17 ? 460 GLY D O 1 +ATOM 12693 N N . LYS D 2 461 ? -51.201 -29.042 -99.792 1.00 54.71 ? 461 LYS D N 1 +ATOM 12694 C CA . LYS D 2 461 ? -50.974 -29.517 -101.151 1.00 58.17 ? 461 LYS D CA 1 +ATOM 12695 C C . LYS D 2 461 ? -51.413 -30.973 -101.226 1.00 64.66 ? 461 LYS D C 1 +ATOM 12696 O O . LYS D 2 461 ? -50.895 -31.813 -100.484 1.00 60.86 ? 461 LYS D O 1 +ATOM 12697 C CB . LYS D 2 461 ? -49.497 -29.364 -101.542 1.00 57.21 ? 461 LYS D CB 1 +ATOM 12698 C CG . LYS D 2 461 ? -48.976 -27.927 -101.465 1.00 51.82 ? 461 LYS D CG 1 +ATOM 12699 C CD . LYS D 2 461 ? -47.469 -27.822 -101.688 1.00 51.15 ? 461 LYS D CD 1 +ATOM 12700 C CE . LYS D 2 461 ? -47.090 -28.085 -103.141 1.00 72.11 ? 461 LYS D CE 1 +ATOM 12701 N NZ . LYS D 2 461 ? -47.740 -27.156 -104.113 1.00 77.89 ? 461 LYS D NZ 1 +ATOM 12702 N N . HIS D 2 462 ? -52.378 -31.268 -102.107 1.00 65.77 ? 462 HIS D N 1 +ATOM 12703 C CA . HIS D 2 462 ? -52.880 -32.628 -102.274 1.00 60.29 ? 462 HIS D CA 1 +ATOM 12704 C C . HIS D 2 462 ? -52.357 -33.315 -103.525 1.00 61.54 ? 462 HIS D C 1 +ATOM 12705 O O . HIS D 2 462 ? -52.333 -34.548 -103.570 1.00 64.72 ? 462 HIS D O 1 +ATOM 12706 C CB . HIS D 2 462 ? -54.415 -32.649 -102.303 1.00 55.84 ? 462 HIS D CB 1 +ATOM 12707 C CG . HIS D 2 462 ? -55.016 -31.926 -103.467 1.00 59.37 ? 462 HIS D CG 1 +ATOM 12708 N ND1 . HIS D 2 462 ? -55.621 -30.694 -103.344 1.00 63.19 ? 462 HIS D ND1 1 +ATOM 12709 C CD2 . HIS D 2 462 ? -55.125 -32.268 -104.772 1.00 62.49 ? 462 HIS D CD2 1 +ATOM 12710 C CE1 . HIS D 2 462 ? -56.072 -30.305 -104.523 1.00 61.25 ? 462 HIS D CE1 1 +ATOM 12711 N NE2 . HIS D 2 462 ? -55.780 -31.241 -105.408 1.00 66.88 ? 462 HIS D NE2 1 +ATOM 12712 N N . SER D 2 463 ? -51.948 -32.557 -104.538 1.00 61.35 ? 463 SER D N 1 +ATOM 12713 C CA . SER D 2 463 ? -51.334 -33.128 -105.725 1.00 66.78 ? 463 SER D CA 1 +ATOM 12714 C C . SER D 2 463 ? -49.817 -33.199 -105.609 1.00 70.96 ? 463 SER D C 1 +ATOM 12715 O O . SER D 2 463 ? -49.134 -33.430 -106.614 1.00 78.89 ? 463 SER D O 1 +ATOM 12716 C CB . SER D 2 463 ? -51.743 -32.323 -106.962 1.00 76.16 ? 463 SER D CB 1 +ATOM 12717 O OG . SER D 2 463 ? -51.282 -30.983 -106.888 1.00 74.10 ? 463 SER D OG 1 +ATOM 12718 N N . HIS D 2 464 ? -49.281 -33.039 -104.401 1.00 62.01 ? 464 HIS D N 1 +ATOM 12719 C CA . HIS D 2 464 ? -47.845 -32.955 -104.182 1.00 64.49 ? 464 HIS D CA 1 +ATOM 12720 C C . HIS D 2 464 ? -47.500 -33.686 -102.893 1.00 62.28 ? 464 HIS D C 1 +ATOM 12721 O O . HIS D 2 464 ? -48.235 -33.593 -101.906 1.00 61.58 ? 464 HIS D O 1 +ATOM 12722 C CB . HIS D 2 464 ? -47.403 -31.485 -104.113 1.00 61.42 ? 464 HIS D CB 1 +ATOM 12723 C CG . HIS D 2 464 ? -45.920 -31.281 -104.166 1.00 65.12 ? 464 HIS D CG 1 +ATOM 12724 N ND1 . HIS D 2 464 ? -45.055 -31.832 -103.246 1.00 62.28 ? 464 HIS D ND1 1 +ATOM 12725 C CD2 . HIS D 2 464 ? -45.153 -30.557 -105.016 1.00 67.40 ? 464 HIS D CD2 1 +ATOM 12726 C CE1 . HIS D 2 464 ? -43.818 -31.471 -103.535 1.00 65.88 ? 464 HIS D CE1 1 +ATOM 12727 N NE2 . HIS D 2 464 ? -43.849 -30.696 -104.604 1.00 70.80 ? 464 HIS D NE2 1 +ATOM 12728 N N . ASP D 2 465 ? -46.392 -34.429 -102.916 1.00 66.52 ? 465 ASP D N 1 +ATOM 12729 C CA . ASP D 2 465 ? -45.877 -35.141 -101.744 1.00 65.38 ? 465 ASP D CA 1 +ATOM 12730 C C . ASP D 2 465 ? -44.480 -34.610 -101.437 1.00 63.39 ? 465 ASP D C 1 +ATOM 12731 O O . ASP D 2 465 ? -43.512 -34.952 -102.123 1.00 62.80 ? 465 ASP D O 1 +ATOM 12732 C CB . ASP D 2 465 ? -45.855 -36.652 -101.975 1.00 63.79 ? 465 ASP D CB 1 +ATOM 12733 C CG . ASP D 2 465 ? -47.212 -37.205 -102.368 1.00 70.31 ? 465 ASP D CG 1 +ATOM 12734 O OD1 . ASP D 2 465 ? -48.237 -36.610 -101.971 1.00 69.42 ? 465 ASP D OD1 1 +ATOM 12735 O OD2 . ASP D 2 465 ? -47.255 -38.246 -103.060 1.00 76.08 ? 465 ASP D OD2 1 +ATOM 12736 N N . GLU D 2 466 ? -44.371 -33.776 -100.407 1.00 62.33 ? 466 GLU D N 1 +ATOM 12737 C CA . GLU D 2 466 ? -43.093 -33.172 -100.038 1.00 58.34 ? 466 GLU D CA 1 +ATOM 12738 C C . GLU D 2 466 ? -42.203 -34.227 -99.400 1.00 58.06 ? 466 GLU D C 1 +ATOM 12739 O O . GLU D 2 466 ? -42.352 -34.556 -98.222 1.00 53.28 ? 466 GLU D O 1 +ATOM 12740 C CB . GLU D 2 466 ? -43.315 -31.997 -99.094 1.00 68.05 ? 466 GLU D CB 1 +ATOM 12741 C CG . GLU D 2 466 ? -42.034 -31.315 -98.655 1.00 64.82 ? 466 GLU D CG 1 +ATOM 12742 C CD . GLU D 2 466 ? -41.311 -30.626 -99.796 1.00 66.66 ? 466 GLU D CD 1 +ATOM 12743 O OE1 . GLU D 2 466 ? -41.932 -30.386 -100.856 1.00 68.29 ? 466 GLU D OE1 1 +ATOM 12744 O OE2 . GLU D 2 466 ? -40.112 -30.324 -99.631 1.00 68.92 ? 466 GLU D OE2 1 +ATOM 12745 N N . MET D 2 467 ? -41.264 -34.760 -100.183 1.00 62.84 ? 467 MET D N 1 +ATOM 12746 C CA . MET D 2 467 ? -40.382 -35.814 -99.696 1.00 64.37 ? 467 MET D CA 1 +ATOM 12747 C C . MET D 2 467 ? -39.328 -35.303 -98.721 1.00 57.41 ? 467 MET D C 1 +ATOM 12748 O O . MET D 2 467 ? -38.697 -36.118 -98.039 1.00 55.56 ? 467 MET D O 1 +ATOM 12749 C CB . MET D 2 467 ? -39.710 -36.523 -100.876 1.00 64.82 ? 467 MET D CB 1 +ATOM 12750 C CG . MET D 2 467 ? -40.677 -37.183 -101.863 1.00 64.57 ? 467 MET D CG 1 +ATOM 12751 S SD . MET D 2 467 ? -41.757 -38.421 -101.106 1.00 65.50 ? 467 MET D SD 1 +ATOM 12752 C CE . MET D 2 467 ? -40.531 -39.558 -100.465 1.00 57.12 ? 467 MET D CE 1 +ATOM 12753 N N . SER D 2 468 ? -39.123 -33.986 -98.636 1.00 56.30 ? 468 SER D N 1 +ATOM 12754 C CA . SER D 2 468 ? -38.100 -33.456 -97.742 1.00 52.46 ? 468 SER D CA 1 +ATOM 12755 C C . SER D 2 468 ? -38.399 -33.782 -96.287 1.00 57.22 ? 468 SER D C 1 +ATOM 12756 O O . SER D 2 468 ? -37.473 -33.894 -95.476 1.00 65.29 ? 468 SER D O 1 +ATOM 12757 C CB . SER D 2 468 ? -37.982 -31.943 -97.916 1.00 53.65 ? 468 SER D CB 1 +ATOM 12758 O OG . SER D 2 468 ? -37.683 -31.603 -99.256 1.00 68.26 ? 468 SER D OG 1 +ATOM 12759 N N . ILE D 2 469 ? -39.676 -33.947 -95.938 1.00 55.12 ? 469 ILE D N 1 +ATOM 12760 C CA . ILE D 2 469 ? -40.036 -34.254 -94.557 1.00 55.08 ? 469 ILE D CA 1 +ATOM 12761 C C . ILE D 2 469 ? -39.559 -35.643 -94.166 1.00 57.27 ? 469 ILE D C 1 +ATOM 12762 O O . ILE D 2 469 ? -39.203 -35.885 -93.005 1.00 49.66 ? 469 ILE D O 1 +ATOM 12763 C CB . ILE D 2 469 ? -41.555 -34.109 -94.372 1.00 50.36 ? 469 ILE D CB 1 +ATOM 12764 C CG1 . ILE D 2 469 ? -42.004 -32.727 -94.837 1.00 53.11 ? 469 ILE D CG1 1 +ATOM 12765 C CG2 . ILE D 2 469 ? -41.946 -34.347 -92.922 1.00 50.50 ? 469 ILE D CG2 1 +ATOM 12766 C CD1 . ILE D 2 469 ? -43.495 -32.546 -94.820 1.00 58.11 ? 469 ILE D CD1 1 +ATOM 12767 N N . LEU D 2 470 ? -39.541 -36.574 -95.119 1.00 56.67 ? 470 LEU D N 1 +ATOM 12768 C CA . LEU D 2 470 ? -39.159 -37.953 -94.853 1.00 53.93 ? 470 LEU D CA 1 +ATOM 12769 C C . LEU D 2 470 ? -37.660 -38.122 -94.623 1.00 56.23 ? 470 LEU D C 1 +ATOM 12770 O O . LEU D 2 470 ? -37.251 -39.166 -94.104 1.00 54.48 ? 470 LEU D O 1 +ATOM 12771 C CB . LEU D 2 470 ? -39.619 -38.833 -96.018 1.00 49.04 ? 470 LEU D CB 1 +ATOM 12772 C CG . LEU D 2 470 ? -40.478 -40.064 -95.717 1.00 47.26 ? 470 LEU D CG 1 +ATOM 12773 C CD1 . LEU D 2 470 ? -39.640 -41.179 -95.141 1.00 52.75 ? 470 LEU D CD1 1 +ATOM 12774 C CD2 . LEU D 2 470 ? -41.578 -39.711 -94.762 1.00 52.42 ? 470 LEU D CD2 1 +ATOM 12775 N N . VAL D 2 471 ? -36.848 -37.115 -94.969 1.00 55.25 ? 471 VAL D N 1 +ATOM 12776 C CA . VAL D 2 471 ? -35.390 -37.278 -94.900 1.00 50.08 ? 471 VAL D CA 1 +ATOM 12777 C C . VAL D 2 471 ? -34.919 -37.695 -93.516 1.00 51.18 ? 471 VAL D C 1 +ATOM 12778 O O . VAL D 2 471 ? -33.961 -38.477 -93.425 1.00 53.45 ? 471 VAL D O 1 +ATOM 12779 C CB . VAL D 2 471 ? -34.694 -36.012 -95.424 1.00 48.78 ? 471 VAL D CB 1 +ATOM 12780 C CG1 . VAL D 2 471 ? -33.187 -36.158 -95.346 1.00 51.27 ? 471 VAL D CG1 1 +ATOM 12781 C CG2 . VAL D 2 471 ? -35.127 -35.733 -96.851 1.00 47.96 ? 471 VAL D CG2 1 +ATOM 12782 N N . PRO D 2 472 ? -35.491 -37.207 -92.408 1.00 55.09 ? 472 PRO D N 1 +ATOM 12783 C CA . PRO D 2 472 ? -35.167 -37.807 -91.100 1.00 57.33 ? 472 PRO D CA 1 +ATOM 12784 C C . PRO D 2 472 ? -35.280 -39.325 -91.074 1.00 53.43 ? 472 PRO D C 1 +ATOM 12785 O O . PRO D 2 472 ? -34.468 -39.995 -90.423 1.00 47.57 ? 472 PRO D O 1 +ATOM 12786 C CB . PRO D 2 472 ? -36.194 -37.161 -90.158 1.00 55.63 ? 472 PRO D CB 1 +ATOM 12787 C CG . PRO D 2 472 ? -36.652 -35.908 -90.842 1.00 57.19 ? 472 PRO D CG 1 +ATOM 12788 C CD . PRO D 2 472 ? -36.123 -35.885 -92.252 1.00 57.91 ? 472 PRO D CD 1 +ATOM 12789 N N . LEU D 2 473 ? -36.274 -39.885 -91.763 1.00 52.98 ? 473 LEU D N 1 +ATOM 12790 C CA . LEU D 2 473 ? -36.473 -41.328 -91.740 1.00 50.67 ? 473 LEU D CA 1 +ATOM 12791 C C . LEU D 2 473 ? -35.561 -42.031 -92.738 1.00 53.64 ? 473 LEU D C 1 +ATOM 12792 O O . LEU D 2 473 ? -35.041 -43.113 -92.446 1.00 59.47 ? 473 LEU D O 1 +ATOM 12793 C CB . LEU D 2 473 ? -37.941 -41.657 -92.013 1.00 47.31 ? 473 LEU D CB 1 +ATOM 12794 C CG . LEU D 2 473 ? -38.364 -43.121 -91.920 1.00 41.87 ? 473 LEU D CG 1 +ATOM 12795 C CD1 . LEU D 2 473 ? -37.932 -43.674 -90.580 1.00 45.19 ? 473 LEU D CD1 1 +ATOM 12796 C CD2 . LEU D 2 473 ? -39.871 -43.265 -92.083 1.00 38.00 ? 473 LEU D CD2 1 +ATOM 12797 N N . THR D 2 474 ? -35.345 -41.434 -93.914 1.00 49.35 ? 474 THR D N 1 +ATOM 12798 C CA . THR D 2 474 ? -34.465 -42.052 -94.901 1.00 50.81 ? 474 THR D CA 1 +ATOM 12799 C C . THR D 2 474 ? -33.001 -42.019 -94.474 1.00 56.17 ? 474 THR D C 1 +ATOM 12800 O O . THR D 2 474 ? -32.197 -42.787 -95.012 1.00 62.42 ? 474 THR D O 1 +ATOM 12801 C CB . THR D 2 474 ? -34.606 -41.374 -96.266 1.00 51.11 ? 474 THR D CB 1 +ATOM 12802 O OG1 . THR D 2 474 ? -34.186 -40.009 -96.176 1.00 58.80 ? 474 THR D OG1 1 +ATOM 12803 C CG2 . THR D 2 474 ? -36.047 -41.424 -96.742 1.00 48.77 ? 474 THR D CG2 1 +ATOM 12804 N N . GLN D 2 475 ? -32.630 -41.135 -93.550 1.00 56.29 ? 475 GLN D N 1 +ATOM 12805 C CA . GLN D 2 475 ? -31.264 -41.085 -93.046 1.00 57.74 ? 475 GLN D CA 1 +ATOM 12806 C C . GLN D 2 475 ? -31.078 -41.857 -91.754 1.00 55.24 ? 475 GLN D C 1 +ATOM 12807 O O . GLN D 2 475 ? -29.981 -42.360 -91.498 1.00 62.32 ? 475 GLN D O 1 +ATOM 12808 C CB . GLN D 2 475 ? -30.830 -39.633 -92.823 1.00 64.19 ? 475 GLN D CB 1 +ATOM 12809 C CG . GLN D 2 475 ? -30.733 -38.826 -94.103 1.00 69.72 ? 475 GLN D CG 1 +ATOM 12810 C CD . GLN D 2 475 ? -30.358 -37.380 -93.858 1.00 70.68 ? 475 GLN D CD 1 +ATOM 12811 O OE1 . GLN D 2 475 ? -30.479 -36.873 -92.742 1.00 69.19 ? 475 GLN D OE1 1 +ATOM 12812 N NE2 . GLN D 2 475 ? -29.905 -36.704 -94.908 1.00 75.60 ? 475 GLN D NE2 1 +ATOM 12813 N N . CYS D 2 476 ? -32.121 -41.961 -90.937 1.00 55.02 ? 476 CYS D N 1 +ATOM 12814 C CA . CYS D 2 476 ? -32.015 -42.689 -89.681 1.00 65.09 ? 476 CYS D CA 1 +ATOM 12815 C C . CYS D 2 476 ? -32.395 -44.151 -89.827 1.00 62.88 ? 476 CYS D C 1 +ATOM 12816 O O . CYS D 2 476 ? -31.736 -45.023 -89.251 1.00 66.65 ? 476 CYS D O 1 +ATOM 12817 C CB . CYS D 2 476 ? -32.887 -42.025 -88.615 1.00 66.97 ? 476 CYS D CB 1 +ATOM 12818 S SG . CYS D 2 476 ? -32.108 -40.589 -87.865 1.00 81.71 ? 476 CYS D SG 1 +ATOM 12819 N N . CYS D 2 477 ? -33.460 -44.424 -90.569 1.00 55.15 ? 477 CYS D N 1 +ATOM 12820 C CA . CYS D 2 477 ? -33.882 -45.782 -90.887 1.00 56.82 ? 477 CYS D CA 1 +ATOM 12821 C C . CYS D 2 477 ? -34.065 -46.625 -89.630 1.00 50.82 ? 477 CYS D C 1 +ATOM 12822 O O . CYS D 2 477 ? -33.382 -47.624 -89.402 1.00 55.60 ? 477 CYS D O 1 +ATOM 12823 C CB . CYS D 2 477 ? -32.904 -46.438 -91.852 1.00 60.22 ? 477 CYS D CB 1 +ATOM 12824 S SG . CYS D 2 477 ? -33.324 -46.060 -93.542 1.00 80.89 ? 477 CYS D SG 1 +ATOM 12825 N N . ARG D 2 478 ? -35.019 -46.200 -88.814 1.00 46.85 ? 478 ARG D N 1 +ATOM 12826 C CA . ARG D 2 478 ? -35.442 -46.993 -87.675 1.00 57.07 ? 478 ARG D CA 1 +ATOM 12827 C C . ARG D 2 478 ? -36.767 -46.439 -87.188 1.00 53.89 ? 478 ARG D C 1 +ATOM 12828 O O . ARG D 2 478 ? -36.994 -45.234 -87.255 1.00 59.25 ? 478 ARG D O 1 +ATOM 12829 C CB . ARG D 2 478 ? -34.393 -47.001 -86.558 1.00 58.24 ? 478 ARG D CB 1 +ATOM 12830 C CG . ARG D 2 478 ? -33.979 -45.652 -86.055 1.00 61.54 ? 478 ARG D CG 1 +ATOM 12831 C CD . ARG D 2 478 ? -33.088 -45.782 -84.831 1.00 76.08 ? 478 ARG D CD 1 +ATOM 12832 N NE . ARG D 2 478 ? -32.328 -47.031 -84.808 1.00 88.44 ? 478 ARG D NE 1 +ATOM 12833 C CZ . ARG D 2 478 ? -32.602 -48.055 -84.006 1.00 88.14 ? 478 ARG D CZ 1 +ATOM 12834 N NH1 . ARG D 2 478 ? -33.624 -47.974 -83.167 1.00 78.17 ? 478 ARG D NH1 1 +ATOM 12835 N NH2 . ARG D 2 478 ? -31.861 -49.157 -84.041 1.00 81.70 ? 478 ARG D NH2 1 +ATOM 12836 N N . VAL D 2 479 ? -37.657 -47.332 -86.752 1.00 52.86 ? 479 VAL D N 1 +ATOM 12837 C CA . VAL D 2 479 ? -39.005 -46.958 -86.352 1.00 50.93 ? 479 VAL D CA 1 +ATOM 12838 C C . VAL D 2 479 ? -39.445 -47.841 -85.195 1.00 57.97 ? 479 VAL D C 1 +ATOM 12839 O O . VAL D 2 479 ? -38.874 -48.902 -84.934 1.00 62.17 ? 479 VAL D O 1 +ATOM 12840 C CB . VAL D 2 479 ? -40.021 -47.074 -87.510 1.00 48.91 ? 479 VAL D CB 1 +ATOM 12841 C CG1 . VAL D 2 479 ? -39.886 -45.897 -88.456 1.00 48.34 ? 479 VAL D CG1 1 +ATOM 12842 C CG2 . VAL D 2 479 ? -39.835 -48.388 -88.243 1.00 56.17 ? 479 VAL D CG2 1 +ATOM 12843 N N . LYS D 2 480 ? -40.502 -47.402 -84.526 1.00 62.30 ? 480 LYS D N 1 +ATOM 12844 C CA . LYS D 2 480 ? -41.055 -48.144 -83.408 1.00 69.88 ? 480 LYS D CA 1 +ATOM 12845 C C . LYS D 2 480 ? -41.928 -49.271 -83.943 1.00 67.86 ? 480 LYS D C 1 +ATOM 12846 O O . LYS D 2 480 ? -42.781 -49.047 -84.810 1.00 65.54 ? 480 LYS D O 1 +ATOM 12847 C CB . LYS D 2 480 ? -41.853 -47.202 -82.504 1.00 68.10 ? 480 LYS D CB 1 +ATOM 12848 C CG . LYS D 2 480 ? -42.293 -47.788 -81.170 1.00 67.82 ? 480 LYS D CG 1 +ATOM 12849 C CD . LYS D 2 480 ? -43.094 -46.759 -80.388 1.00 64.61 ? 480 LYS D CD 1 +ATOM 12850 C CE . LYS D 2 480 ? -42.277 -45.496 -80.164 1.00 57.07 ? 480 LYS D CE 1 +ATOM 12851 N NZ . LYS D 2 480 ? -43.079 -44.419 -79.525 1.00 52.87 ? 480 LYS D NZ 1 +ATOM 12852 N N . ARG D 2 481 ? -41.683 -50.494 -83.459 1.00 61.85 ? 481 ARG D N 1 +ATOM 12853 C CA . ARG D 2 481 ? -42.428 -51.640 -83.973 1.00 62.68 ? 481 ARG D CA 1 +ATOM 12854 C C . ARG D 2 481 ? -43.929 -51.431 -83.824 1.00 60.78 ? 481 ARG D C 1 +ATOM 12855 O O . ARG D 2 481 ? -44.704 -51.790 -84.721 1.00 55.09 ? 481 ARG D O 1 +ATOM 12856 C CB . ARG D 2 481 ? -41.990 -52.922 -83.264 1.00 68.00 ? 481 ARG D CB 1 +ATOM 12857 C CG . ARG D 2 481 ? -42.738 -54.159 -83.754 1.00 76.12 ? 481 ARG D CG 1 +ATOM 12858 C CD . ARG D 2 481 ? -42.257 -55.453 -83.107 1.00 74.85 ? 481 ARG D CD 1 +ATOM 12859 N NE . ARG D 2 481 ? -43.025 -56.595 -83.598 1.00 73.50 ? 481 ARG D NE 1 +ATOM 12860 C CZ . ARG D 2 481 ? -42.781 -57.862 -83.281 1.00 75.33 ? 481 ARG D CZ 1 +ATOM 12861 N NH1 . ARG D 2 481 ? -43.540 -58.829 -83.782 1.00 72.65 ? 481 ARG D NH1 1 +ATOM 12862 N NH2 . ARG D 2 481 ? -41.769 -58.164 -82.480 1.00 80.24 ? 481 ARG D NH2 1 +ATOM 12863 N N . SER D 2 482 ? -44.349 -50.798 -82.723 1.00 57.28 ? 482 SER D N 1 +ATOM 12864 C CA . SER D 2 482 ? -45.757 -50.466 -82.525 1.00 58.08 ? 482 SER D CA 1 +ATOM 12865 C C . SER D 2 482 ? -46.311 -49.683 -83.700 1.00 54.92 ? 482 SER D C 1 +ATOM 12866 O O . SER D 2 482 ? -47.430 -49.936 -84.159 1.00 52.16 ? 482 SER D O 1 +ATOM 12867 C CB . SER D 2 482 ? -45.926 -49.650 -81.245 1.00 59.94 ? 482 SER D CB 1 +ATOM 12868 O OG . SER D 2 482 ? -47.262 -49.206 -81.088 1.00 67.52 ? 482 SER D OG 1 +ATOM 12869 N N . THR D 2 483 ? -45.539 -48.729 -84.200 1.00 60.19 ? 483 THR D N 1 +ATOM 12870 C CA . THR D 2 483 ? -46.024 -47.912 -85.297 1.00 64.51 ? 483 THR D CA 1 +ATOM 12871 C C . THR D 2 483 ? -45.911 -48.636 -86.632 1.00 59.97 ? 483 THR D C 1 +ATOM 12872 O O . THR D 2 483 ? -46.789 -48.484 -87.488 1.00 55.04 ? 483 THR D O 1 +ATOM 12873 C CB . THR D 2 483 ? -45.257 -46.588 -85.328 1.00 67.68 ? 483 THR D CB 1 +ATOM 12874 O OG1 . THR D 2 483 ? -43.924 -46.813 -85.806 1.00 63.05 ? 483 THR D OG1 1 +ATOM 12875 C CG2 . THR D 2 483 ? -45.188 -46.000 -83.926 1.00 60.03 ? 483 THR D CG2 1 +ATOM 12876 N N . TYR D 2 484 ? -44.874 -49.457 -86.813 1.00 56.33 ? 484 TYR D N 1 +ATOM 12877 C CA . TYR D 2 484 ? -44.717 -50.157 -88.083 1.00 59.97 ? 484 TYR D CA 1 +ATOM 12878 C C . TYR D 2 484 ? -45.898 -51.085 -88.335 1.00 60.89 ? 484 TYR D C 1 +ATOM 12879 O O . TYR D 2 484 ? -46.530 -51.033 -89.398 1.00 55.32 ? 484 TYR D O 1 +ATOM 12880 C CB . TYR D 2 484 ? -43.403 -50.938 -88.103 1.00 55.23 ? 484 TYR D CB 1 +ATOM 12881 C CG . TYR D 2 484 ? -42.951 -51.328 -89.496 1.00 51.52 ? 484 TYR D CG 1 +ATOM 12882 C CD1 . TYR D 2 484 ? -43.638 -50.888 -90.620 1.00 52.60 ? 484 TYR D CD1 1 +ATOM 12883 C CD2 . TYR D 2 484 ? -41.848 -52.146 -89.688 1.00 51.47 ? 484 TYR D CD2 1 +ATOM 12884 C CE1 . TYR D 2 484 ? -43.234 -51.242 -91.892 1.00 53.74 ? 484 TYR D CE1 1 +ATOM 12885 C CE2 . TYR D 2 484 ? -41.436 -52.506 -90.959 1.00 51.58 ? 484 TYR D CE2 1 +ATOM 12886 C CZ . TYR D 2 484 ? -42.134 -52.048 -92.056 1.00 51.32 ? 484 TYR D CZ 1 +ATOM 12887 O OH . TYR D 2 484 ? -41.739 -52.392 -93.327 1.00 50.71 ? 484 TYR D OH 1 +ATOM 12888 N N . LEU D 2 485 ? -46.233 -51.919 -87.351 1.00 61.03 ? 485 LEU D N 1 +ATOM 12889 C CA . LEU D 2 485 ? -47.370 -52.812 -87.523 1.00 59.02 ? 485 LEU D CA 1 +ATOM 12890 C C . LEU D 2 485 ? -48.660 -52.032 -87.729 1.00 64.34 ? 485 LEU D C 1 +ATOM 12891 O O . LEU D 2 485 ? -49.516 -52.452 -88.516 1.00 70.12 ? 485 LEU D O 1 +ATOM 12892 C CB . LEU D 2 485 ? -47.491 -53.736 -86.315 1.00 55.64 ? 485 LEU D CB 1 +ATOM 12893 C CG . LEU D 2 485 ? -46.283 -54.624 -86.040 1.00 61.99 ? 485 LEU D CG 1 +ATOM 12894 C CD1 . LEU D 2 485 ? -46.559 -55.474 -84.819 1.00 70.93 ? 485 LEU D CD1 1 +ATOM 12895 C CD2 . LEU D 2 485 ? -45.965 -55.488 -87.255 1.00 70.98 ? 485 LEU D CD2 1 +ATOM 12896 N N . ARG D 2 486 ? -48.802 -50.878 -87.071 1.00 58.04 ? 486 ARG D N 1 +ATOM 12897 C CA . ARG D 2 486 ? -49.975 -50.045 -87.315 1.00 52.89 ? 486 ARG D CA 1 +ATOM 12898 C C . ARG D 2 486 ? -49.980 -49.529 -88.746 1.00 56.45 ? 486 ARG D C 1 +ATOM 12899 O O . ARG D 2 486 ? -50.972 -49.688 -89.465 1.00 59.44 ? 486 ARG D O 1 +ATOM 12900 C CB . ARG D 2 486 ? -50.038 -48.889 -86.318 1.00 54.20 ? 486 ARG D CB 1 +ATOM 12901 C CG . ARG D 2 486 ? -50.489 -49.287 -84.914 1.00 59.17 ? 486 ARG D CG 1 +ATOM 12902 C CD . ARG D 2 486 ? -50.902 -48.061 -84.110 1.00 55.48 ? 486 ARG D CD 1 +ATOM 12903 N NE . ARG D 2 486 ? -50.005 -47.794 -82.988 1.00 59.30 ? 486 ARG D NE 1 +ATOM 12904 C CZ . ARG D 2 486 ? -50.183 -48.261 -81.757 1.00 66.93 ? 486 ARG D CZ 1 +ATOM 12905 N NH1 . ARG D 2 486 ? -51.228 -49.028 -81.478 1.00 68.51 ? 486 ARG D NH1 1 +ATOM 12906 N NH2 . ARG D 2 486 ? -49.313 -47.960 -80.803 1.00 70.33 ? 486 ARG D NH2 1 +ATOM 12907 N N . LEU D 2 487 ? -48.873 -48.918 -89.182 1.00 56.42 ? 487 LEU D N 1 +ATOM 12908 C CA . LEU D 2 487 ? -48.827 -48.346 -90.526 1.00 56.98 ? 487 LEU D CA 1 +ATOM 12909 C C . LEU D 2 487 ? -49.141 -49.390 -91.590 1.00 60.52 ? 487 LEU D C 1 +ATOM 12910 O O . LEU D 2 487 ? -49.842 -49.099 -92.567 1.00 58.49 ? 487 LEU D O 1 +ATOM 12911 C CB . LEU D 2 487 ? -47.458 -47.724 -90.790 1.00 53.34 ? 487 LEU D CB 1 +ATOM 12912 C CG . LEU D 2 487 ? -47.092 -46.525 -89.922 1.00 55.35 ? 487 LEU D CG 1 +ATOM 12913 C CD1 . LEU D 2 487 ? -45.745 -45.961 -90.347 1.00 54.29 ? 487 LEU D CD1 1 +ATOM 12914 C CD2 . LEU D 2 487 ? -48.188 -45.472 -89.992 1.00 51.47 ? 487 LEU D CD2 1 +ATOM 12915 N N . GLN D 2 488 ? -48.648 -50.618 -91.412 1.00 63.98 ? 488 GLN D N 1 +ATOM 12916 C CA . GLN D 2 488 ? -49.041 -51.702 -92.308 1.00 63.50 ? 488 GLN D CA 1 +ATOM 12917 C C . GLN D 2 488 ? -50.531 -51.976 -92.200 1.00 62.19 ? 488 GLN D C 1 +ATOM 12918 O O . GLN D 2 488 ? -51.226 -52.109 -93.213 1.00 65.40 ? 488 GLN D O 1 +ATOM 12919 C CB . GLN D 2 488 ? -48.245 -52.964 -91.993 1.00 60.85 ? 488 GLN D CB 1 +ATOM 12920 C CG . GLN D 2 488 ? -46.786 -52.877 -92.348 1.00 59.25 ? 488 GLN D CG 1 +ATOM 12921 C CD . GLN D 2 488 ? -45.995 -54.010 -91.749 1.00 63.99 ? 488 GLN D CD 1 +ATOM 12922 O OE1 . GLN D 2 488 ? -46.345 -54.530 -90.688 1.00 67.66 ? 488 GLN D OE1 1 +ATOM 12923 N NE2 . GLN D 2 488 ? -44.926 -54.411 -92.427 1.00 68.82 ? 488 GLN D NE2 1 +ATOM 12924 N N . LEU D 2 489 ? -51.041 -52.045 -90.970 1.00 57.11 ? 489 LEU D N 1 +ATOM 12925 C CA . LEU D 2 489 ? -52.458 -52.307 -90.767 1.00 60.28 ? 489 LEU D CA 1 +ATOM 12926 C C . LEU D 2 489 ? -53.321 -51.204 -91.362 1.00 61.88 ? 489 LEU D C 1 +ATOM 12927 O O . LEU D 2 489 ? -54.416 -51.475 -91.869 1.00 62.35 ? 489 LEU D O 1 +ATOM 12928 C CB . LEU D 2 489 ? -52.741 -52.456 -89.277 1.00 56.93 ? 489 LEU D CB 1 +ATOM 12929 C CG . LEU D 2 489 ? -54.164 -52.863 -88.928 1.00 60.91 ? 489 LEU D CG 1 +ATOM 12930 C CD1 . LEU D 2 489 ? -54.381 -54.321 -89.273 1.00 65.95 ? 489 LEU D CD1 1 +ATOM 12931 C CD2 . LEU D 2 489 ? -54.416 -52.607 -87.461 1.00 70.61 ? 489 LEU D CD2 1 +ATOM 12932 N N . LEU D 2 490 ? -52.847 -49.963 -91.319 1.00 59.14 ? 490 LEU D N 1 +ATOM 12933 C CA . LEU D 2 490 ? -53.586 -48.842 -91.880 1.00 55.07 ? 490 LEU D CA 1 +ATOM 12934 C C . LEU D 2 490 ? -53.476 -48.770 -93.395 1.00 54.60 ? 490 LEU D C 1 +ATOM 12935 O O . LEU D 2 490 ? -53.905 -47.773 -93.982 1.00 58.67 ? 490 LEU D O 1 +ATOM 12936 C CB . LEU D 2 490 ? -53.104 -47.524 -91.261 1.00 53.68 ? 490 LEU D CB 1 +ATOM 12937 C CG . LEU D 2 490 ? -53.704 -47.029 -89.935 1.00 45.03 ? 490 LEU D CG 1 +ATOM 12938 C CD1 . LEU D 2 490 ? -55.124 -47.527 -89.754 1.00 51.74 ? 490 LEU D CD1 1 +ATOM 12939 C CD2 . LEU D 2 490 ? -52.850 -47.389 -88.735 1.00 50.15 ? 490 LEU D CD2 1 +ATOM 12940 N N . ALA D 2 491 ? -52.920 -49.795 -94.040 1.00 56.29 ? 491 ALA D N 1 +ATOM 12941 C CA . ALA D 2 491 ? -52.796 -49.830 -95.490 1.00 54.29 ? 491 ALA D CA 1 +ATOM 12942 C C . ALA D 2 491 ? -53.678 -50.884 -96.140 1.00 55.15 ? 491 ALA D C 1 +ATOM 12943 O O . ALA D 2 491 ? -53.675 -50.997 -97.369 1.00 52.64 ? 491 ALA D O 1 +ATOM 12944 C CB . ALA D 2 491 ? -51.335 -50.067 -95.888 1.00 52.17 ? 491 ALA D CB 1 +ATOM 12945 N N . LYS D 2 492 ? -54.429 -51.655 -95.353 1.00 61.91 ? 492 LYS D N 1 +ATOM 12946 C CA . LYS D 2 492 ? -55.302 -52.700 -95.876 1.00 64.25 ? 492 LYS D CA 1 +ATOM 12947 C C . LYS D 2 492 ? -56.663 -52.116 -96.233 1.00 67.84 ? 492 LYS D C 1 +ATOM 12948 O O . LYS D 2 492 ? -57.182 -51.251 -95.522 1.00 70.22 ? 492 LYS D O 1 +ATOM 12949 C CB . LYS D 2 492 ? -55.474 -53.824 -94.849 1.00 58.80 ? 492 LYS D CB 1 +ATOM 12950 C CG . LYS D 2 492 ? -54.402 -54.907 -94.894 1.00 57.76 ? 492 LYS D CG 1 +ATOM 12951 C CD . LYS D 2 492 ? -53.033 -54.346 -94.536 1.00 60.57 ? 492 LYS D CD 1 +ATOM 12952 C CE . LYS D 2 492 ? -51.903 -55.263 -94.983 1.00 80.16 ? 492 LYS D CE 1 +ATOM 12953 N NZ . LYS D 2 492 ? -50.565 -54.601 -94.891 1.00 72.88 ? 492 LYS D NZ 1 +ATOM 12954 N N . GLU D 2 493 ? -57.256 -52.620 -97.321 1.00 64.36 ? 493 GLU D N 1 +ATOM 12955 C CA . GLU D 2 493 ? -58.502 -52.037 -97.815 1.00 66.84 ? 493 GLU D CA 1 +ATOM 12956 C C . GLU D 2 493 ? -59.624 -52.130 -96.788 1.00 69.21 ? 493 GLU D C 1 +ATOM 12957 O O . GLU D 2 493 ? -60.532 -51.291 -96.788 1.00 67.29 ? 493 GLU D O 1 +ATOM 12958 C CB . GLU D 2 493 ? -58.921 -52.709 -99.123 1.00 64.57 ? 493 GLU D CB 1 +ATOM 12959 C CG . GLU D 2 493 ? -58.943 -51.767 -100.321 1.00 74.96 ? 493 GLU D CG 1 +ATOM 12960 C CD . GLU D 2 493 ? -60.093 -50.769 -100.272 1.00 84.86 ? 493 GLU D CD 1 +ATOM 12961 O OE1 . GLU D 2 493 ? -61.088 -51.029 -99.558 1.00 84.65 ? 493 GLU D OE1 1 +ATOM 12962 O OE2 . GLU D 2 493 ? -60.001 -49.722 -100.953 1.00 81.97 ? 493 GLU D OE2 1 +ATOM 12963 N N . GLU D 2 494 ? -59.591 -53.144 -95.918 1.00 72.22 ? 494 GLU D N 1 +ATOM 12964 C CA . GLU D 2 494 ? -60.606 -53.263 -94.874 1.00 78.45 ? 494 GLU D CA 1 +ATOM 12965 C C . GLU D 2 494 ? -60.466 -52.178 -93.812 1.00 73.37 ? 494 GLU D C 1 +ATOM 12966 O O . GLU D 2 494 ? -61.453 -51.824 -93.155 1.00 68.06 ? 494 GLU D O 1 +ATOM 12967 C CB . GLU D 2 494 ? -60.563 -54.653 -94.236 1.00 75.78 ? 494 GLU D CB 1 +ATOM 12968 C CG . GLU D 2 494 ? -59.181 -55.203 -93.942 1.00 72.45 ? 494 GLU D CG 1 +ATOM 12969 C CD . GLU D 2 494 ? -58.645 -56.042 -95.092 1.00 81.97 ? 494 GLU D CD 1 +ATOM 12970 O OE1 . GLU D 2 494 ? -58.502 -55.499 -96.209 1.00 85.82 ? 494 GLU D OE1 1 +ATOM 12971 O OE2 . GLU D 2 494 ? -58.399 -57.252 -94.888 1.00 81.60 ? 494 GLU D OE2 1 +ATOM 12972 N N . TYR D 2 495 ? -59.258 -51.664 -93.607 1.00 71.65 ? 495 TYR D N 1 +ATOM 12973 C CA . TYR D 2 495 ? -59.058 -50.592 -92.641 1.00 71.18 ? 495 TYR D CA 1 +ATOM 12974 C C . TYR D 2 495 ? -58.736 -49.280 -93.347 1.00 74.81 ? 495 TYR D C 1 +ATOM 12975 O O . TYR D 2 495 ? -59.616 -48.429 -93.511 1.00 81.28 ? 495 TYR D O 1 +ATOM 12976 C CB . TYR D 2 495 ? -57.953 -50.969 -91.657 1.00 66.26 ? 495 TYR D CB 1 +ATOM 12977 C CG . TYR D 2 495 ? -58.366 -52.046 -90.685 1.00 67.99 ? 495 TYR D CG 1 +ATOM 12978 C CD1 . TYR D 2 495 ? -59.684 -52.482 -90.617 1.00 72.89 ? 495 TYR D CD1 1 +ATOM 12979 C CD2 . TYR D 2 495 ? -57.448 -52.606 -89.815 1.00 65.65 ? 495 TYR D CD2 1 +ATOM 12980 C CE1 . TYR D 2 495 ? -60.071 -53.462 -89.717 1.00 77.76 ? 495 TYR D CE1 1 +ATOM 12981 C CE2 . TYR D 2 495 ? -57.823 -53.584 -88.909 1.00 71.69 ? 495 TYR D CE2 1 +ATOM 12982 C CZ . TYR D 2 495 ? -59.134 -54.008 -88.863 1.00 73.19 ? 495 TYR D CZ 1 +ATOM 12983 O OH . TYR D 2 495 ? -59.500 -54.980 -87.960 1.00 67.26 ? 495 TYR D OH 1 +ATOM 12984 N N . LYS D 2 496 ? -57.480 -49.113 -93.756 1.00 71.66 ? 496 LYS D N 1 +ATOM 12985 C CA . LYS D 2 496 ? -57.015 -47.981 -94.554 1.00 71.60 ? 496 LYS D CA 1 +ATOM 12986 C C . LYS D 2 496 ? -57.232 -46.632 -93.874 1.00 64.65 ? 496 LYS D C 1 +ATOM 12987 O O . LYS D 2 496 ? -57.846 -46.549 -92.807 1.00 61.02 ? 496 LYS D O 1 +ATOM 12988 C CB . LYS D 2 496 ? -57.666 -48.011 -95.947 1.00 70.96 ? 496 LYS D CB 1 +ATOM 12989 C CG . LYS D 2 496 ? -58.888 -47.131 -96.173 1.00 66.86 ? 496 LYS D CG 1 +ATOM 12990 C CD . LYS D 2 496 ? -59.417 -47.349 -97.590 1.00 74.39 ? 496 LYS D CD 1 +ATOM 12991 C CE . LYS D 2 496 ? -58.292 -47.228 -98.625 1.00 71.47 ? 496 LYS D CE 1 +ATOM 12992 N NZ . LYS D 2 496 ? -58.732 -47.536 -100.017 1.00 70.95 ? 496 LYS D NZ 1 +ATOM 12993 N N . LEU D 2 497 ? -56.722 -45.569 -94.490 1.00 67.83 ? 497 LEU D N 1 +ATOM 12994 C CA . LEU D 2 497 ? -56.715 -44.240 -93.895 1.00 64.71 ? 497 LEU D CA 1 +ATOM 12995 C C . LEU D 2 497 ? -57.886 -43.372 -94.328 1.00 66.38 ? 497 LEU D C 1 +ATOM 12996 O O . LEU D 2 497 ? -58.500 -42.720 -93.480 1.00 72.12 ? 497 LEU D O 1 +ATOM 12997 C CB . LEU D 2 497 ? -55.400 -43.530 -94.232 1.00 59.37 ? 497 LEU D CB 1 +ATOM 12998 C CG . LEU D 2 497 ? -54.462 -43.243 -93.063 1.00 46.69 ? 497 LEU D CG 1 +ATOM 12999 C CD1 . LEU D 2 497 ? -54.849 -41.957 -92.392 1.00 50.78 ? 497 LEU D CD1 1 +ATOM 13000 C CD2 . LEU D 2 497 ? -54.543 -44.365 -92.073 1.00 51.54 ? 497 LEU D CD2 1 +ATOM 13001 N N . SER D 2 498 ? -58.219 -43.350 -95.620 1.00 62.53 ? 498 SER D N 1 +ATOM 13002 C CA . SER D 2 498 ? -59.261 -42.443 -96.095 1.00 69.50 ? 498 SER D CA 1 +ATOM 13003 C C . SER D 2 498 ? -60.598 -42.733 -95.421 1.00 75.10 ? 498 SER D C 1 +ATOM 13004 O O . SER D 2 498 ? -61.213 -41.841 -94.823 1.00 71.14 ? 498 SER D O 1 +ATOM 13005 C CB . SER D 2 498 ? -59.390 -42.537 -97.619 1.00 73.42 ? 498 SER D CB 1 +ATOM 13006 O OG . SER D 2 498 ? -59.780 -43.834 -98.037 1.00 78.34 ? 498 SER D OG 1 +ATOM 13007 N N . SER D 2 499 ? -61.043 -43.989 -95.470 1.00 72.66 ? 499 SER D N 1 +ATOM 13008 C CA . SER D 2 499 ? -62.320 -44.340 -94.861 1.00 72.67 ? 499 SER D CA 1 +ATOM 13009 C C . SER D 2 499 ? -62.279 -44.199 -93.341 1.00 76.35 ? 499 SER D C 1 +ATOM 13010 O O . SER D 2 499 ? -63.307 -43.904 -92.720 1.00 79.73 ? 499 SER D O 1 +ATOM 13011 C CB . SER D 2 499 ? -62.715 -45.754 -95.283 1.00 73.73 ? 499 SER D CB 1 +ATOM 13012 O OG . SER D 2 499 ? -61.781 -46.703 -94.801 1.00 79.42 ? 499 SER D OG 1 +ATOM 13013 N N . LEU D 2 500 ? -61.107 -44.385 -92.728 1.00 71.39 ? 500 LEU D N 1 +ATOM 13014 C CA . LEU D 2 500 ? -60.973 -44.150 -91.293 1.00 69.15 ? 500 LEU D CA 1 +ATOM 13015 C C . LEU D 2 500 ? -60.886 -42.669 -90.963 1.00 62.68 ? 500 LEU D C 1 +ATOM 13016 O O . LEU D 2 500 ? -61.295 -42.256 -89.873 1.00 67.47 ? 500 LEU D O 1 +ATOM 13017 C CB . LEU D 2 500 ? -59.743 -44.869 -90.735 1.00 65.87 ? 500 LEU D CB 1 +ATOM 13018 C CG . LEU D 2 500 ? -59.948 -46.321 -90.307 1.00 67.29 ? 500 LEU D CG 1 +ATOM 13019 C CD1 . LEU D 2 500 ? -58.654 -46.929 -89.809 1.00 64.14 ? 500 LEU D CD1 1 +ATOM 13020 C CD2 . LEU D 2 500 ? -61.005 -46.389 -89.221 1.00 71.34 ? 500 LEU D CD2 1 +ATOM 13021 N N . MET D 2 501 ? -60.331 -41.863 -91.864 1.00 56.64 ? 501 MET D N 1 +ATOM 13022 C CA . MET D 2 501 ? -60.179 -40.448 -91.562 1.00 60.39 ? 501 MET D CA 1 +ATOM 13023 C C . MET D 2 501 ? -61.470 -39.681 -91.824 1.00 61.15 ? 501 MET D C 1 +ATOM 13024 O O . MET D 2 501 ? -61.852 -38.823 -91.024 1.00 64.49 ? 501 MET D O 1 +ATOM 13025 C CB . MET D 2 501 ? -59.011 -39.875 -92.368 1.00 66.59 ? 501 MET D CB 1 +ATOM 13026 C CG . MET D 2 501 ? -58.474 -38.513 -91.927 1.00 58.10 ? 501 MET D CG 1 +ATOM 13027 S SD . MET D 2 501 ? -57.658 -38.471 -90.314 1.00 47.99 ? 501 MET D SD 1 +ATOM 13028 C CE . MET D 2 501 ? -57.042 -40.143 -90.159 1.00 55.31 ? 501 MET D CE 1 +ATOM 13029 N N . GLU D 2 502 ? -62.173 -39.979 -92.919 1.00 58.08 ? 502 GLU D N 1 +ATOM 13030 C CA . GLU D 2 502 ? -63.446 -39.302 -93.140 1.00 61.84 ? 502 GLU D CA 1 +ATOM 13031 C C . GLU D 2 502 ? -64.512 -39.735 -92.140 1.00 64.51 ? 502 GLU D C 1 +ATOM 13032 O O . GLU D 2 502 ? -65.510 -39.026 -91.976 1.00 59.82 ? 502 GLU D O 1 +ATOM 13033 C CB . GLU D 2 502 ? -63.946 -39.530 -94.565 1.00 68.98 ? 502 GLU D CB 1 +ATOM 13034 C CG . GLU D 2 502 ? -64.480 -40.919 -94.824 1.00 81.72 ? 502 GLU D CG 1 +ATOM 13035 C CD . GLU D 2 502 ? -65.076 -41.060 -96.212 1.00 84.57 ? 502 GLU D CD 1 +ATOM 13036 O OE1 . GLU D 2 502 ? -65.214 -40.034 -96.916 1.00 68.18 ? 502 GLU D OE1 1 +ATOM 13037 O OE2 . GLU D 2 502 ? -65.408 -42.202 -96.595 1.00 97.61 ? 502 GLU D OE2 1 +ATOM 13038 N N . GLU D 2 503 ? -64.333 -40.882 -91.478 1.00 67.30 ? 503 GLU D N 1 +ATOM 13039 C CA . GLU D 2 503 ? -65.279 -41.306 -90.450 1.00 65.51 ? 503 GLU D CA 1 +ATOM 13040 C C . GLU D 2 503 ? -65.247 -40.367 -89.246 1.00 62.04 ? 503 GLU D C 1 +ATOM 13041 O O . GLU D 2 503 ? -66.255 -39.735 -88.911 1.00 61.68 ? 503 GLU D O 1 +ATOM 13042 C CB . GLU D 2 503 ? -64.981 -42.746 -90.023 1.00 68.14 ? 503 GLU D CB 1 +ATOM 13043 C CG . GLU D 2 503 ? -65.723 -43.182 -88.760 1.00 85.99 ? 503 GLU D CG 1 +ATOM 13044 C CD . GLU D 2 503 ? -66.935 -44.061 -89.041 1.00 94.25 ? 503 GLU D CD 1 +ATOM 13045 O OE1 . GLU D 2 503 ? -66.756 -45.158 -89.617 1.00 96.40 ? 503 GLU D OE1 1 +ATOM 13046 O OE2 . GLU D 2 503 ? -68.065 -43.656 -88.680 1.00 84.82 ? 503 GLU D OE2 1 +ATOM 13047 N N . SER D 2 504 ? -64.091 -40.259 -88.582 1.00 60.98 ? 504 SER D N 1 +ATOM 13048 C CA . SER D 2 504 ? -64.017 -39.444 -87.371 1.00 65.70 ? 504 SER D CA 1 +ATOM 13049 C C . SER D 2 504 ? -64.122 -37.956 -87.690 1.00 64.95 ? 504 SER D C 1 +ATOM 13050 O O . SER D 2 504 ? -64.705 -37.193 -86.912 1.00 71.36 ? 504 SER D O 1 +ATOM 13051 C CB . SER D 2 504 ? -62.729 -39.740 -86.604 1.00 60.62 ? 504 SER D CB 1 +ATOM 13052 O OG . SER D 2 504 ? -61.588 -39.515 -87.406 1.00 60.13 ? 504 SER D OG 1 +ATOM 13053 N N . LEU D 2 505 ? -63.541 -37.521 -88.813 1.00 61.38 ? 505 LEU D N 1 +ATOM 13054 C CA . LEU D 2 505 ? -63.683 -36.132 -89.244 1.00 65.30 ? 505 LEU D CA 1 +ATOM 13055 C C . LEU D 2 505 ? -65.123 -35.778 -89.587 1.00 69.57 ? 505 LEU D C 1 +ATOM 13056 O O . LEU D 2 505 ? -65.456 -34.590 -89.681 1.00 67.86 ? 505 LEU D O 1 +ATOM 13057 C CB . LEU D 2 505 ? -62.797 -35.856 -90.456 1.00 67.05 ? 505 LEU D CB 1 +ATOM 13058 C CG . LEU D 2 505 ? -61.295 -35.806 -90.182 1.00 71.22 ? 505 LEU D CG 1 +ATOM 13059 C CD1 . LEU D 2 505 ? -60.538 -35.494 -91.462 1.00 71.30 ? 505 LEU D CD1 1 +ATOM 13060 C CD2 . LEU D 2 505 ? -60.965 -34.798 -89.089 1.00 71.64 ? 505 LEU D CD2 1 +ATOM 13061 N N . LEU D 2 506 ? -65.977 -36.779 -89.805 1.00 66.44 ? 506 LEU D N 1 +ATOM 13062 C CA . LEU D 2 506 ? -67.387 -36.517 -90.040 1.00 59.24 ? 506 LEU D CA 1 +ATOM 13063 C C . LEU D 2 506 ? -68.092 -36.068 -88.768 1.00 62.04 ? 506 LEU D C 1 +ATOM 13064 O O . LEU D 2 506 ? -69.183 -35.494 -88.843 1.00 63.02 ? 506 LEU D O 1 +ATOM 13065 C CB . LEU D 2 506 ? -68.054 -37.774 -90.600 1.00 56.63 ? 506 LEU D CB 1 +ATOM 13066 C CG . LEU D 2 506 ? -69.433 -37.661 -91.247 1.00 62.77 ? 506 LEU D CG 1 +ATOM 13067 C CD1 . LEU D 2 506 ? -69.352 -36.901 -92.559 1.00 64.95 ? 506 LEU D CD1 1 +ATOM 13068 C CD2 . LEU D 2 506 ? -70.033 -39.041 -91.456 1.00 62.53 ? 506 LEU D CD2 1 +ATOM 13069 N N . GLN D 2 507 ? -67.475 -36.289 -87.608 1.00 64.49 ? 507 GLN D N 1 +ATOM 13070 C CA . GLN D 2 507 ? -68.044 -35.883 -86.325 1.00 65.45 ? 507 GLN D CA 1 +ATOM 13071 C C . GLN D 2 507 ? -67.414 -34.561 -85.885 1.00 64.14 ? 507 GLN D C 1 +ATOM 13072 O O . GLN D 2 507 ? -66.615 -34.488 -84.955 1.00 69.05 ? 507 GLN D O 1 +ATOM 13073 C CB . GLN D 2 507 ? -67.840 -36.986 -85.285 1.00 63.49 ? 507 GLN D CB 1 +ATOM 13074 C CG . GLN D 2 507 ? -68.375 -36.678 -83.886 1.00 79.93 ? 507 GLN D CG 1 +ATOM 13075 C CD . GLN D 2 507 ? -69.762 -36.059 -83.897 1.00 96.23 ? 507 GLN D CD 1 +ATOM 13076 O OE1 . GLN D 2 507 ? -70.669 -36.547 -84.576 1.00 103.85 ? 507 GLN D OE1 1 +ATOM 13077 N NE2 . GLN D 2 507 ? -69.934 -34.978 -83.140 1.00 86.06 ? 507 GLN D NE2 1 +ATOM 13078 N N . ASP D 2 508 ? -67.778 -33.500 -86.604 1.00 62.25 ? 508 ASP D N 1 +ATOM 13079 C CA . ASP D 2 508 ? -67.339 -32.154 -86.259 1.00 65.44 ? 508 ASP D CA 1 +ATOM 13080 C C . ASP D 2 508 ? -68.240 -31.160 -86.973 1.00 66.95 ? 508 ASP D C 1 +ATOM 13081 O O . ASP D 2 508 ? -68.526 -31.324 -88.162 1.00 65.79 ? 508 ASP D O 1 +ATOM 13082 C CB . ASP D 2 508 ? -65.873 -31.914 -86.646 1.00 64.37 ? 508 ASP D CB 1 +ATOM 13083 C CG . ASP D 2 508 ? -65.272 -30.688 -85.961 1.00 66.12 ? 508 ASP D CG 1 +ATOM 13084 O OD1 . ASP D 2 508 ? -65.935 -30.085 -85.087 1.00 64.15 ? 508 ASP D OD1 1 +ATOM 13085 O OD2 . ASP D 2 508 ? -64.128 -30.322 -86.304 1.00 63.74 ? 508 ASP D OD2 1 +ATOM 13086 N N . ARG D 2 509 ? -68.637 -30.100 -86.264 1.00 68.40 ? 509 ARG D N 1 +ATOM 13087 C CA . ARG D 2 509 ? -69.537 -29.108 -86.843 1.00 67.22 ? 509 ARG D CA 1 +ATOM 13088 C C . ARG D 2 509 ? -68.817 -28.294 -87.910 1.00 59.94 ? 509 ARG D C 1 +ATOM 13089 O O . ARG D 2 509 ? -68.971 -27.072 -87.988 1.00 63.96 ? 509 ARG D O 1 +ATOM 13090 C CB . ARG D 2 509 ? -70.113 -28.188 -85.763 1.00 63.29 ? 509 ARG D CB 1 +ATOM 13091 C CG . ARG D 2 509 ? -71.385 -27.453 -86.187 1.00 61.83 ? 509 ARG D CG 1 +ATOM 13092 C CD . ARG D 2 509 ? -71.467 -26.079 -85.543 1.00 74.75 ? 509 ARG D CD 1 +ATOM 13093 N NE . ARG D 2 509 ? -72.371 -25.177 -86.253 1.00 75.36 ? 509 ARG D NE 1 +ATOM 13094 C CZ . ARG D 2 509 ? -73.680 -25.096 -86.036 1.00 88.33 ? 509 ARG D CZ 1 +ATOM 13095 N NH1 . ARG D 2 509 ? -74.418 -24.242 -86.734 1.00 82.90 ? 509 ARG D NH1 1 +ATOM 13096 N NH2 . ARG D 2 509 ? -74.253 -25.866 -85.121 1.00 96.22 ? 509 ARG D NH2 1 +ATOM 13097 N N . LEU D 2 510 ? -68.010 -28.962 -88.723 1.00 52.33 ? 510 LEU D N 1 +ATOM 13098 C CA . LEU D 2 510 ? -67.294 -28.290 -89.789 1.00 58.37 ? 510 LEU D CA 1 +ATOM 13099 C C . LEU D 2 510 ? -67.159 -29.133 -91.048 1.00 61.12 ? 510 LEU D C 1 +ATOM 13100 O O . LEU D 2 510 ? -66.575 -28.652 -92.024 1.00 63.28 ? 510 LEU D O 1 +ATOM 13101 C CB . LEU D 2 510 ? -65.907 -27.840 -89.311 1.00 58.20 ? 510 LEU D CB 1 +ATOM 13102 C CG . LEU D 2 510 ? -65.670 -26.332 -89.449 1.00 56.22 ? 510 LEU D CG 1 +ATOM 13103 C CD1 . LEU D 2 510 ? -66.496 -25.774 -90.600 1.00 57.78 ? 510 LEU D CD1 1 +ATOM 13104 C CD2 . LEU D 2 510 ? -65.988 -25.592 -88.170 1.00 49.84 ? 510 LEU D CD2 1 +ATOM 13105 N N . VAL D 2 511 ? -67.658 -30.366 -91.055 1.00 62.79 ? 511 VAL D N 1 +ATOM 13106 C CA . VAL D 2 511 ? -67.520 -31.274 -92.193 1.00 64.13 ? 511 VAL D CA 1 +ATOM 13107 C C . VAL D 2 511 ? -68.059 -30.589 -93.449 1.00 58.76 ? 511 VAL D C 1 +ATOM 13108 O O . VAL D 2 511 ? -69.084 -29.890 -93.388 1.00 54.92 ? 511 VAL D O 1 +ATOM 13109 C CB . VAL D 2 511 ? -68.226 -32.614 -91.900 1.00 61.26 ? 511 VAL D CB 1 +ATOM 13110 C CG1 . VAL D 2 511 ? -69.754 -32.493 -92.000 1.00 53.58 ? 511 VAL D CG1 1 +ATOM 13111 C CG2 . VAL D 2 511 ? -67.686 -33.742 -92.776 1.00 56.34 ? 511 VAL D CG2 1 +ATOM 13112 N N . PRO D 2 512 ? -67.386 -30.724 -94.606 1.00 53.78 ? 512 PRO D N 1 +ATOM 13113 C CA . PRO D 2 512 ? -66.126 -31.447 -94.813 1.00 53.51 ? 512 PRO D CA 1 +ATOM 13114 C C . PRO D 2 512 ? -64.892 -30.662 -94.385 1.00 56.26 ? 512 PRO D C 1 +ATOM 13115 O O . PRO D 2 512 ? -64.579 -29.649 -95.007 1.00 54.31 ? 512 PRO D O 1 +ATOM 13116 C CB . PRO D 2 512 ? -66.097 -31.681 -96.330 1.00 50.36 ? 512 PRO D CB 1 +ATOM 13117 C CG . PRO D 2 512 ? -67.427 -31.198 -96.852 1.00 52.57 ? 512 PRO D CG 1 +ATOM 13118 C CD . PRO D 2 512 ? -67.901 -30.186 -95.871 1.00 50.80 ? 512 PRO D CD 1 +ATOM 13119 N N . VAL D 2 513 ? -64.203 -31.130 -93.340 1.00 57.02 ? 513 VAL D N 1 +ATOM 13120 C CA . VAL D 2 513 ? -62.987 -30.452 -92.901 1.00 57.37 ? 513 VAL D CA 1 +ATOM 13121 C C . VAL D 2 513 ? -61.854 -30.675 -93.896 1.00 61.77 ? 513 VAL D C 1 +ATOM 13122 O O . VAL D 2 513 ? -60.986 -29.808 -94.065 1.00 60.11 ? 513 VAL D O 1 +ATOM 13123 C CB . VAL D 2 513 ? -62.597 -30.916 -91.485 1.00 53.76 ? 513 VAL D CB 1 +ATOM 13124 C CG1 . VAL D 2 513 ? -63.744 -30.676 -90.521 1.00 62.66 ? 513 VAL D CG1 1 +ATOM 13125 C CG2 . VAL D 2 513 ? -62.211 -32.378 -91.490 1.00 51.66 ? 513 VAL D CG2 1 +ATOM 13126 N N . LEU D 2 514 ? -61.842 -31.824 -94.570 1.00 62.64 ? 514 LEU D N 1 +ATOM 13127 C CA . LEU D 2 514 ? -60.851 -32.150 -95.588 1.00 56.00 ? 514 LEU D CA 1 +ATOM 13128 C C . LEU D 2 514 ? -61.572 -32.464 -96.886 1.00 57.57 ? 514 LEU D C 1 +ATOM 13129 O O . LEU D 2 514 ? -62.375 -33.402 -96.942 1.00 55.22 ? 514 LEU D O 1 +ATOM 13130 C CB . LEU D 2 514 ? -59.990 -33.341 -95.168 1.00 48.20 ? 514 LEU D CB 1 +ATOM 13131 C CG . LEU D 2 514 ? -58.930 -33.079 -94.108 1.00 45.41 ? 514 LEU D CG 1 +ATOM 13132 C CD1 . LEU D 2 514 ? -58.097 -34.319 -93.881 1.00 41.33 ? 514 LEU D CD1 1 +ATOM 13133 C CD2 . LEU D 2 514 ? -58.060 -31.926 -94.559 1.00 48.67 ? 514 LEU D CD2 1 +ATOM 13134 N N . ILE D 2 515 ? -61.260 -31.702 -97.935 1.00 59.84 ? 515 ILE D N 1 +ATOM 13135 C CA . ILE D 2 515 ? -61.742 -32.053 -99.260 1.00 61.40 ? 515 ILE D CA 1 +ATOM 13136 C C . ILE D 2 515 ? -61.219 -33.449 -99.605 1.00 62.72 ? 515 ILE D C 1 +ATOM 13137 O O . ILE D 2 515 ? -60.201 -33.908 -99.069 1.00 59.34 ? 515 ILE D O 1 +ATOM 13138 C CB . ILE D 2 515 ? -61.317 -30.997 -100.298 1.00 61.03 ? 515 ILE D CB 1 +ATOM 13139 C CG1 . ILE D 2 515 ? -62.123 -31.139 -101.595 1.00 66.25 ? 515 ILE D CG1 1 +ATOM 13140 C CG2 . ILE D 2 515 ? -59.817 -31.058 -100.567 1.00 57.87 ? 515 ILE D CG2 1 +ATOM 13141 C CD1 . ILE D 2 515 ? -63.606 -30.857 -101.428 1.00 63.82 ? 515 ILE D CD1 1 +ATOM 13142 N N . LYS D 2 516 ? -61.959 -34.155 -100.458 1.00 63.62 ? 516 LYS D N 1 +ATOM 13143 C CA . LYS D 2 516 ? -61.658 -35.563 -100.705 1.00 65.17 ? 516 LYS D CA 1 +ATOM 13144 C C . LYS D 2 516 ? -60.240 -35.823 -101.214 1.00 60.39 ? 516 LYS D C 1 +ATOM 13145 O O . LYS D 2 516 ? -59.663 -36.853 -100.822 1.00 60.03 ? 516 LYS D O 1 +ATOM 13146 C CB . LYS D 2 516 ? -62.700 -36.152 -101.667 1.00 64.81 ? 516 LYS D CB 1 +ATOM 13147 C CG . LYS D 2 516 ? -62.697 -37.674 -101.702 1.00 67.18 ? 516 LYS D CG 1 +ATOM 13148 C CD . LYS D 2 516 ? -63.907 -38.231 -102.432 1.00 70.70 ? 516 LYS D CD 1 +ATOM 13149 C CE . LYS D 2 516 ? -63.973 -39.748 -102.293 1.00 73.97 ? 516 LYS D CE 1 +ATOM 13150 N NZ . LYS D 2 516 ? -65.210 -40.321 -102.899 1.00 75.11 ? 516 LYS D NZ 1 +ATOM 13151 N N . PRO D 2 517 ? -59.629 -34.981 -102.063 1.00 58.56 ? 517 PRO D N 1 +ATOM 13152 C CA . PRO D 2 517 ? -58.240 -35.257 -102.475 1.00 55.03 ? 517 PRO D CA 1 +ATOM 13153 C C . PRO D 2 517 ? -57.272 -35.452 -101.321 1.00 56.25 ? 517 PRO D C 1 +ATOM 13154 O O . PRO D 2 517 ? -56.375 -36.298 -101.413 1.00 55.72 ? 517 PRO D O 1 +ATOM 13155 C CB . PRO D 2 517 ? -57.882 -34.016 -103.303 1.00 52.21 ? 517 PRO D CB 1 +ATOM 13156 C CG . PRO D 2 517 ? -59.163 -33.598 -103.895 1.00 56.13 ? 517 PRO D CG 1 +ATOM 13157 C CD . PRO D 2 517 ? -60.211 -33.879 -102.856 1.00 56.98 ? 517 PRO D CD 1 +ATOM 13158 N N . HIS D 2 518 ? -57.438 -34.704 -100.227 1.00 60.68 ? 518 HIS D N 1 +ATOM 13159 C CA . HIS D 2 518 ? -56.537 -34.855 -99.087 1.00 61.84 ? 518 HIS D CA 1 +ATOM 13160 C C . HIS D 2 518 ? -56.773 -36.176 -98.367 1.00 63.32 ? 518 HIS D C 1 +ATOM 13161 O O . HIS D 2 518 ? -55.815 -36.850 -97.967 1.00 61.25 ? 518 HIS D O 1 +ATOM 13162 C CB . HIS D 2 518 ? -56.702 -33.675 -98.127 1.00 51.65 ? 518 HIS D CB 1 +ATOM 13163 C CG . HIS D 2 518 ? -56.125 -32.391 -98.641 1.00 53.55 ? 518 HIS D CG 1 +ATOM 13164 N ND1 . HIS D 2 518 ? -56.907 -31.316 -99.006 1.00 55.25 ? 518 HIS D ND1 1 +ATOM 13165 C CD2 . HIS D 2 518 ? -54.842 -32.006 -98.838 1.00 53.01 ? 518 HIS D CD2 1 +ATOM 13166 C CE1 . HIS D 2 518 ? -56.133 -30.326 -99.414 1.00 51.06 ? 518 HIS D CE1 1 +ATOM 13167 N NE2 . HIS D 2 518 ? -54.875 -30.718 -99.320 1.00 54.20 ? 518 HIS D NE2 1 +ATOM 13168 N N . LEU D 2 519 ? -58.038 -36.566 -98.191 1.00 65.94 ? 519 LEU D N 1 +ATOM 13169 C CA . LEU D 2 519 ? -58.329 -37.847 -97.555 1.00 66.20 ? 519 LEU D CA 1 +ATOM 13170 C C . LEU D 2 519 ? -57.734 -38.995 -98.354 1.00 66.31 ? 519 LEU D C 1 +ATOM 13171 O O . LEU D 2 519 ? -57.254 -39.980 -97.783 1.00 66.97 ? 519 LEU D O 1 +ATOM 13172 C CB . LEU D 2 519 ? -59.839 -38.039 -97.411 1.00 67.36 ? 519 LEU D CB 1 +ATOM 13173 C CG . LEU D 2 519 ? -60.585 -37.123 -96.444 1.00 70.45 ? 519 LEU D CG 1 +ATOM 13174 C CD1 . LEU D 2 519 ? -62.081 -37.196 -96.701 1.00 77.85 ? 519 LEU D CD1 1 +ATOM 13175 C CD2 . LEU D 2 519 ? -60.270 -37.518 -95.009 1.00 65.52 ? 519 LEU D CD2 1 +ATOM 13176 N N . GLU D 2 520 ? -57.753 -38.877 -99.680 1.00 66.58 ? 520 GLU D N 1 +ATOM 13177 C CA . GLU D 2 520 ? -57.214 -39.921 -100.537 1.00 70.59 ? 520 GLU D CA 1 +ATOM 13178 C C . GLU D 2 520 ? -55.693 -39.851 -100.603 1.00 67.48 ? 520 GLU D C 1 +ATOM 13179 O O . GLU D 2 520 ? -55.019 -40.888 -100.619 1.00 62.66 ? 520 GLU D O 1 +ATOM 13180 C CB . GLU D 2 520 ? -57.839 -39.797 -101.926 1.00 74.82 ? 520 GLU D CB 1 +ATOM 13181 C CG . GLU D 2 520 ? -57.599 -40.964 -102.852 1.00 87.39 ? 520 GLU D CG 1 +ATOM 13182 C CD . GLU D 2 520 ? -58.199 -40.725 -104.222 1.00 89.49 ? 520 GLU D CD 1 +ATOM 13183 O OE1 . GLU D 2 520 ? -59.041 -39.809 -104.346 1.00 69.19 ? 520 GLU D OE1 1 +ATOM 13184 O OE2 . GLU D 2 520 ? -57.837 -41.454 -105.170 1.00 118.91 ? 520 GLU D OE2 1 +ATOM 13185 N N . ALA D 2 521 ? -55.137 -38.636 -100.602 1.00 67.26 ? 521 ALA D N 1 +ATOM 13186 C CA . ALA D 2 521 ? -53.687 -38.487 -100.579 1.00 65.53 ? 521 ALA D CA 1 +ATOM 13187 C C . ALA D 2 521 ? -53.085 -39.089 -99.319 1.00 63.19 ? 521 ALA D C 1 +ATOM 13188 O O . ALA D 2 521 ? -51.920 -39.499 -99.326 1.00 66.71 ? 521 ALA D O 1 +ATOM 13189 C CB . ALA D 2 521 ? -53.309 -37.011 -100.696 1.00 59.29 ? 521 ALA D CB 1 +ATOM 13190 N N . LEU D 2 522 ? -53.865 -39.165 -98.237 1.00 63.63 ? 522 LEU D N 1 +ATOM 13191 C CA . LEU D 2 522 ? -53.363 -39.730 -96.989 1.00 66.58 ? 522 LEU D CA 1 +ATOM 13192 C C . LEU D 2 522 ? -52.837 -41.148 -97.187 1.00 72.88 ? 522 LEU D C 1 +ATOM 13193 O O . LEU D 2 522 ? -51.783 -41.506 -96.648 1.00 73.89 ? 522 LEU D O 1 +ATOM 13194 C CB . LEU D 2 522 ? -54.469 -39.706 -95.933 1.00 64.33 ? 522 LEU D CB 1 +ATOM 13195 C CG . LEU D 2 522 ? -54.149 -39.080 -94.577 1.00 54.97 ? 522 LEU D CG 1 +ATOM 13196 C CD1 . LEU D 2 522 ? -53.188 -37.926 -94.734 1.00 49.59 ? 522 LEU D CD1 1 +ATOM 13197 C CD2 . LEU D 2 522 ? -55.435 -38.606 -93.920 1.00 55.13 ? 522 LEU D CD2 1 +ATOM 13198 N N . ASP D 2 523 ? -53.548 -41.968 -97.972 1.00 75.74 ? 523 ASP D N 1 +ATOM 13199 C CA . ASP D 2 523 ? -53.071 -43.320 -98.257 1.00 75.15 ? 523 ASP D CA 1 +ATOM 13200 C C . ASP D 2 523 ? -51.841 -43.307 -99.155 1.00 70.96 ? 523 ASP D C 1 +ATOM 13201 O O . ASP D 2 523 ? -50.976 -44.184 -99.036 1.00 66.91 ? 523 ASP D O 1 +ATOM 13202 C CB . ASP D 2 523 ? -54.183 -44.157 -98.896 1.00 76.41 ? 523 ASP D CB 1 +ATOM 13203 C CG . ASP D 2 523 ? -55.374 -44.365 -97.971 1.00 72.40 ? 523 ASP D CG 1 +ATOM 13204 O OD1 . ASP D 2 523 ? -56.262 -43.487 -97.924 1.00 68.96 ? 523 ASP D OD1 1 +ATOM 13205 O OD2 . ASP D 2 523 ? -55.413 -45.408 -97.283 1.00 72.92 ? 523 ASP D OD2 1 +ATOM 13206 N N . ARG D 2 524 ? -51.739 -42.322 -100.047 1.00 67.24 ? 524 ARG D N 1 +ATOM 13207 C CA . ARG D 2 524 ? -50.588 -42.256 -100.939 1.00 67.37 ? 524 ARG D CA 1 +ATOM 13208 C C . ARG D 2 524 ? -49.317 -41.926 -100.167 1.00 67.98 ? 524 ARG D C 1 +ATOM 13209 O O . ARG D 2 524 ? -48.271 -42.546 -100.390 1.00 69.27 ? 524 ARG D O 1 +ATOM 13210 C CB . ARG D 2 524 ? -50.854 -41.232 -102.041 1.00 66.95 ? 524 ARG D CB 1 +ATOM 13211 C CG . ARG D 2 524 ? -49.696 -40.994 -102.984 1.00 62.61 ? 524 ARG D CG 1 +ATOM 13212 C CD . ARG D 2 524 ? -50.074 -39.932 -103.987 1.00 62.72 ? 524 ARG D CD 1 +ATOM 13213 N NE . ARG D 2 524 ? -50.565 -38.728 -103.327 1.00 59.70 ? 524 ARG D NE 1 +ATOM 13214 C CZ . ARG D 2 524 ? -50.907 -37.615 -103.964 1.00 66.87 ? 524 ARG D CZ 1 +ATOM 13215 N NH1 . ARG D 2 524 ? -50.813 -37.547 -105.286 1.00 71.88 ? 524 ARG D NH1 1 +ATOM 13216 N NH2 . ARG D 2 524 ? -51.341 -36.568 -103.278 1.00 65.69 ? 524 ARG D NH2 1 +ATOM 13217 N N . ARG D 2 525 ? -49.391 -40.970 -99.237 1.00 73.00 ? 525 ARG D N 1 +ATOM 13218 C CA . ARG D 2 525 ? -48.238 -40.677 -98.393 1.00 66.07 ? 525 ARG D CA 1 +ATOM 13219 C C . ARG D 2 525 ? -47.924 -41.842 -97.461 1.00 65.65 ? 525 ARG D C 1 +ATOM 13220 O O . ARG D 2 525 ? -46.762 -42.036 -97.086 1.00 67.62 ? 525 ARG D O 1 +ATOM 13221 C CB . ARG D 2 525 ? -48.473 -39.393 -97.592 1.00 60.91 ? 525 ARG D CB 1 +ATOM 13222 C CG . ARG D 2 525 ? -48.359 -38.111 -98.413 1.00 56.62 ? 525 ARG D CG 1 +ATOM 13223 C CD . ARG D 2 525 ? -49.698 -37.397 -98.505 1.00 60.59 ? 525 ARG D CD 1 +ATOM 13224 N NE . ARG D 2 525 ? -49.653 -36.213 -99.359 1.00 60.59 ? 525 ARG D NE 1 +ATOM 13225 C CZ . ARG D 2 525 ? -49.626 -34.965 -98.904 1.00 60.25 ? 525 ARG D CZ 1 +ATOM 13226 N NH1 . ARG D 2 525 ? -49.638 -34.740 -97.599 1.00 71.50 ? 525 ARG D NH1 1 +ATOM 13227 N NH2 . ARG D 2 525 ? -49.590 -33.944 -99.749 1.00 57.85 ? 525 ARG D NH2 1 +ATOM 13228 N N . LEU D 2 526 ? -48.935 -42.621 -97.072 1.00 61.85 ? 526 LEU D N 1 +ATOM 13229 C CA . LEU D 2 526 ? -48.688 -43.752 -96.184 1.00 66.26 ? 526 LEU D CA 1 +ATOM 13230 C C . LEU D 2 526 ? -47.896 -44.852 -96.883 1.00 70.22 ? 526 LEU D C 1 +ATOM 13231 O O . LEU D 2 526 ? -46.993 -45.449 -96.283 1.00 68.61 ? 526 LEU D O 1 +ATOM 13232 C CB . LEU D 2 526 ? -50.007 -44.305 -95.652 1.00 62.86 ? 526 LEU D CB 1 +ATOM 13233 C CG . LEU D 2 526 ? -49.916 -45.622 -94.879 1.00 54.88 ? 526 LEU D CG 1 +ATOM 13234 C CD1 . LEU D 2 526 ? -48.972 -45.528 -93.687 1.00 47.55 ? 526 LEU D CD1 1 +ATOM 13235 C CD2 . LEU D 2 526 ? -51.303 -46.012 -94.432 1.00 57.40 ? 526 LEU D CD2 1 +ATOM 13236 N N . ARG D 2 527 ? -48.237 -45.160 -98.137 1.00 70.63 ? 527 ARG D N 1 +ATOM 13237 C CA . ARG D 2 527 ? -47.534 -46.233 -98.835 1.00 76.85 ? 527 ARG D CA 1 +ATOM 13238 C C . ARG D 2 527 ? -46.093 -45.861 -99.176 1.00 69.44 ? 527 ARG D C 1 +ATOM 13239 O O . ARG D 2 527 ? -45.259 -46.758 -99.343 1.00 67.28 ? 527 ARG D O 1 +ATOM 13240 C CB . ARG D 2 527 ? -48.298 -46.650 -100.096 1.00 75.83 ? 527 ARG D CB 1 +ATOM 13241 C CG . ARG D 2 527 ? -48.360 -45.612 -101.189 1.00 78.32 ? 527 ARG D CG 1 +ATOM 13242 C CD . ARG D 2 527 ? -48.242 -46.281 -102.550 1.00 87.68 ? 527 ARG D CD 1 +ATOM 13243 N NE . ARG D 2 527 ? -48.575 -45.378 -103.645 1.00 90.34 ? 527 ARG D NE 1 +ATOM 13244 C CZ . ARG D 2 527 ? -49.804 -45.196 -104.113 1.00 82.06 ? 527 ARG D CZ 1 +ATOM 13245 N NH1 . ARG D 2 527 ? -50.822 -45.858 -103.576 1.00 77.22 ? 527 ARG D NH1 1 +ATOM 13246 N NH2 . ARG D 2 527 ? -50.014 -44.349 -105.114 1.00 75.17 ? 527 ARG D NH2 1 +ATOM 13247 N N . LEU D 2 528 ? -45.782 -44.568 -99.296 1.00 57.53 ? 528 LEU D N 1 +ATOM 13248 C CA . LEU D 2 528 ? -44.393 -44.163 -99.487 1.00 56.98 ? 528 LEU D CA 1 +ATOM 13249 C C . LEU D 2 528 ? -43.598 -44.303 -98.195 1.00 61.35 ? 528 LEU D C 1 +ATOM 13250 O O . LEU D 2 528 ? -42.421 -44.679 -98.222 1.00 59.44 ? 528 LEU D O 1 +ATOM 13251 C CB . LEU D 2 528 ? -44.326 -42.730 -100.005 1.00 56.73 ? 528 LEU D CB 1 +ATOM 13252 C CG . LEU D 2 528 ? -45.027 -42.501 -101.341 1.00 60.16 ? 528 LEU D CG 1 +ATOM 13253 C CD1 . LEU D 2 528 ? -44.789 -41.079 -101.843 1.00 63.29 ? 528 LEU D CD1 1 +ATOM 13254 C CD2 . LEU D 2 528 ? -44.571 -43.529 -102.364 1.00 61.75 ? 528 LEU D CD2 1 +ATOM 13255 N N . VAL D 2 529 ? -44.217 -43.978 -97.058 1.00 60.59 ? 529 VAL D N 1 +ATOM 13256 C CA . VAL D 2 529 ? -43.578 -44.215 -95.766 1.00 60.22 ? 529 VAL D CA 1 +ATOM 13257 C C . VAL D 2 529 ? -43.334 -45.704 -95.568 1.00 65.50 ? 529 VAL D C 1 +ATOM 13258 O O . VAL D 2 529 ? -42.235 -46.134 -95.194 1.00 62.86 ? 529 VAL D O 1 +ATOM 13259 C CB . VAL D 2 529 ? -44.443 -43.642 -94.631 1.00 49.43 ? 529 VAL D CB 1 +ATOM 13260 C CG1 . VAL D 2 529 ? -43.910 -44.085 -93.273 1.00 50.64 ? 529 VAL D CG1 1 +ATOM 13261 C CG2 . VAL D 2 529 ? -44.497 -42.141 -94.727 1.00 58.30 ? 529 VAL D CG2 1 +ATOM 13262 N N . LEU D 2 530 ? -44.351 -46.517 -95.863 1.00 65.23 ? 530 LEU D N 1 +ATOM 13263 C CA . LEU D 2 530 ? -44.212 -47.958 -95.713 1.00 62.40 ? 530 LEU D CA 1 +ATOM 13264 C C . LEU D 2 530 ? -43.120 -48.500 -96.625 1.00 60.21 ? 530 LEU D C 1 +ATOM 13265 O O . LEU D 2 530 ? -42.364 -49.394 -96.224 1.00 55.73 ? 530 LEU D O 1 +ATOM 13266 C CB . LEU D 2 530 ? -45.562 -48.626 -95.987 1.00 54.81 ? 530 LEU D CB 1 +ATOM 13267 C CG . LEU D 2 530 ? -45.958 -49.788 -95.072 1.00 60.08 ? 530 LEU D CG 1 +ATOM 13268 C CD1 . LEU D 2 530 ? -45.759 -49.416 -93.616 1.00 62.62 ? 530 LEU D CD1 1 +ATOM 13269 C CD2 . LEU D 2 530 ? -47.406 -50.181 -95.316 1.00 60.00 ? 530 LEU D CD2 1 +ATOM 13270 N N . LYS D 2 531 ? -42.973 -47.920 -97.820 1.00 60.72 ? 531 LYS D N 1 +ATOM 13271 C CA . LYS D 2 531 ? -41.955 -48.382 -98.758 1.00 63.99 ? 531 LYS D CA 1 +ATOM 13272 C C . LYS D 2 531 ? -40.565 -47.946 -98.316 1.00 62.16 ? 531 LYS D C 1 +ATOM 13273 O O . LYS D 2 531 ? -39.589 -48.678 -98.509 1.00 67.91 ? 531 LYS D O 1 +ATOM 13274 C CB . LYS D 2 531 ? -42.260 -47.860 -100.165 1.00 69.36 ? 531 LYS D CB 1 +ATOM 13275 C CG . LYS D 2 531 ? -41.354 -48.392 -101.284 1.00 65.21 ? 531 LYS D CG 1 +ATOM 13276 C CD . LYS D 2 531 ? -41.518 -49.895 -101.492 1.00 77.86 ? 531 LYS D CD 1 +ATOM 13277 C CE . LYS D 2 531 ? -42.844 -50.230 -102.176 1.00 88.59 ? 531 LYS D CE 1 +ATOM 13278 N NZ . LYS D 2 531 ? -43.030 -51.695 -102.402 1.00 84.80 ? 531 LYS D NZ 1 +ATOM 13279 N N . VAL D 2 532 ? -40.452 -46.749 -97.737 1.00 57.24 ? 532 VAL D N 1 +ATOM 13280 C CA . VAL D 2 532 ? -39.162 -46.306 -97.217 1.00 58.41 ? 532 VAL D CA 1 +ATOM 13281 C C . VAL D 2 532 ? -38.700 -47.222 -96.093 1.00 58.12 ? 532 VAL D C 1 +ATOM 13282 O O . VAL D 2 532 ? -37.497 -47.461 -95.920 1.00 57.65 ? 532 VAL D O 1 +ATOM 13283 C CB . VAL D 2 532 ? -39.245 -44.835 -96.766 1.00 56.76 ? 532 VAL D CB 1 +ATOM 13284 C CG1 . VAL D 2 532 ? -38.007 -44.449 -95.969 1.00 56.52 ? 532 VAL D CG1 1 +ATOM 13285 C CG2 . VAL D 2 532 ? -39.405 -43.930 -97.971 1.00 50.53 ? 532 VAL D CG2 1 +ATOM 13286 N N . LEU D 2 533 ? -39.641 -47.746 -95.309 1.00 53.62 ? 533 LEU D N 1 +ATOM 13287 C CA . LEU D 2 533 ? -39.283 -48.723 -94.291 1.00 58.63 ? 533 LEU D CA 1 +ATOM 13288 C C . LEU D 2 533 ? -38.824 -50.037 -94.921 1.00 68.87 ? 533 LEU D C 1 +ATOM 13289 O O . LEU D 2 533 ? -37.907 -50.689 -94.409 1.00 68.60 ? 533 LEU D O 1 +ATOM 13290 C CB . LEU D 2 533 ? -40.471 -48.940 -93.356 1.00 57.30 ? 533 LEU D CB 1 +ATOM 13291 C CG . LEU D 2 533 ? -40.955 -47.672 -92.641 1.00 52.01 ? 533 LEU D CG 1 +ATOM 13292 C CD1 . LEU D 2 533 ? -42.109 -47.972 -91.709 1.00 51.42 ? 533 LEU D CD1 1 +ATOM 13293 C CD2 . LEU D 2 533 ? -39.826 -47.006 -91.877 1.00 45.03 ? 533 LEU D CD2 1 +ATOM 13294 N N . SER D 2 534 ? -39.433 -50.425 -96.047 1.00 73.52 ? 534 SER D N 1 +ATOM 13295 C CA . SER D 2 534 ? -39.086 -51.675 -96.723 1.00 72.69 ? 534 SER D CA 1 +ATOM 13296 C C . SER D 2 534 ? -37.772 -51.560 -97.491 1.00 74.69 ? 534 SER D C 1 +ATOM 13297 O O . SER D 2 534 ? -36.924 -52.458 -97.423 1.00 73.73 ? 534 SER D O 1 +ATOM 13298 C CB . SER D 2 534 ? -40.218 -52.083 -97.668 1.00 63.36 ? 534 SER D CB 1 +ATOM 13299 O OG . SER D 2 534 ? -41.447 -52.171 -96.968 1.00 67.89 ? 534 SER D OG 1 +ATOM 13300 N N . ASP D 2 535 ? -37.598 -50.471 -98.247 1.00 75.74 ? 535 ASP D N 1 +ATOM 13301 C CA . ASP D 2 535 ? -36.365 -50.263 -98.996 1.00 73.21 ? 535 ASP D CA 1 +ATOM 13302 C C . ASP D 2 535 ? -35.160 -50.130 -98.083 1.00 72.58 ? 535 ASP D C 1 +ATOM 13303 O O . ASP D 2 535 ? -34.025 -50.292 -98.541 1.00 79.75 ? 535 ASP D O 1 +ATOM 13304 C CB . ASP D 2 535 ? -36.475 -49.019 -99.875 1.00 67.60 ? 535 ASP D CB 1 +ATOM 13305 C CG . ASP D 2 535 ? -37.524 -49.164 -100.954 1.00 83.34 ? 535 ASP D CG 1 +ATOM 13306 O OD1 . ASP D 2 535 ? -37.724 -50.299 -101.435 1.00 87.52 ? 535 ASP D OD1 1 +ATOM 13307 O OD2 . ASP D 2 535 ? -38.143 -48.145 -101.325 1.00 95.56 ? 535 ASP D OD2 1 +ATOM 13308 N N . CYS D 2 536 ? -35.375 -49.826 -96.808 1.00 69.91 ? 536 CYS D N 1 +ATOM 13309 C CA . CYS D 2 536 ? -34.257 -49.670 -95.896 1.00 84.27 ? 536 CYS D CA 1 +ATOM 13310 C C . CYS D 2 536 ? -34.038 -50.882 -95.005 1.00 87.58 ? 536 CYS D C 1 +ATOM 13311 O O . CYS D 2 536 ? -32.890 -51.188 -94.664 1.00 83.97 ? 536 CYS D O 1 +ATOM 13312 C CB . CYS D 2 536 ? -34.459 -48.430 -95.024 1.00 81.36 ? 536 CYS D CB 1 +ATOM 13313 S SG . CYS D 2 536 ? -32.884 -47.787 -94.488 1.00 129.54 ? 536 CYS D SG 1 +ATOM 13314 N N . VAL D 2 537 ? -35.108 -51.592 -94.637 1.00 85.55 ? 537 VAL D N 1 +ATOM 13315 C CA . VAL D 2 537 ? -34.950 -52.804 -93.846 1.00 79.26 ? 537 VAL D CA 1 +ATOM 13316 C C . VAL D 2 537 ? -34.246 -53.902 -94.635 1.00 79.07 ? 537 VAL D C 1 +ATOM 13317 O O . VAL D 2 537 ? -33.742 -54.862 -94.041 1.00 73.84 ? 537 VAL D O 1 +ATOM 13318 C CB . VAL D 2 537 ? -36.319 -53.278 -93.324 1.00 73.32 ? 537 VAL D CB 1 +ATOM 13319 C CG1 . VAL D 2 537 ? -37.108 -53.988 -94.419 1.00 61.20 ? 537 VAL D CG1 1 +ATOM 13320 C CG2 . VAL D 2 537 ? -36.133 -54.167 -92.115 1.00 73.82 ? 537 VAL D CG2 1 +ATOM 13321 N N . GLU D 2 538 ? -34.194 -53.787 -95.962 1.00 83.25 ? 538 GLU D N 1 +ATOM 13322 C CA . GLU D 2 538 ? -33.398 -54.692 -96.778 1.00 80.17 ? 538 GLU D CA 1 +ATOM 13323 C C . GLU D 2 538 ? -31.927 -54.297 -96.821 1.00 84.34 ? 538 GLU D C 1 +ATOM 13324 O O . GLU D 2 538 ? -31.105 -55.091 -97.292 1.00 85.34 ? 538 GLU D O 1 +ATOM 13325 C CB . GLU D 2 538 ? -33.959 -54.756 -98.197 1.00 77.52 ? 538 GLU D CB 1 +ATOM 13326 C CG . GLU D 2 538 ? -33.700 -53.514 -99.019 1.00 81.69 ? 538 GLU D CG 1 +ATOM 13327 C CD . GLU D 2 538 ? -34.189 -53.651 -100.445 1.00 92.57 ? 538 GLU D CD 1 +ATOM 13328 O OE1 . GLU D 2 538 ? -33.357 -53.541 -101.372 1.00 102.87 ? 538 GLU D OE1 1 +ATOM 13329 O OE2 . GLU D 2 538 ? -35.401 -53.901 -100.634 1.00 87.71 ? 538 GLU D OE2 1 +ATOM 13330 N N . LYS D 2 539 ? -31.580 -53.087 -96.368 1.00 79.52 ? 539 LYS D N 1 +ATOM 13331 C CA . LYS D 2 539 ? -30.193 -52.646 -96.329 1.00 77.60 ? 539 LYS D CA 1 +ATOM 13332 C C . LYS D 2 539 ? -29.607 -52.573 -94.927 1.00 75.01 ? 539 LYS D C 1 +ATOM 13333 O O . LYS D 2 539 ? -28.381 -52.508 -94.796 1.00 76.05 ? 539 LYS D O 1 +ATOM 13334 C CB . LYS D 2 539 ? -30.039 -51.276 -97.008 1.00 79.08 ? 539 LYS D CB 1 +ATOM 13335 C CG . LYS D 2 539 ? -30.297 -51.306 -98.511 1.00 90.19 ? 539 LYS D CG 1 +ATOM 13336 C CD . LYS D 2 539 ? -30.048 -49.946 -99.149 1.00 95.34 ? 539 LYS D CD 1 +ATOM 13337 C CE . LYS D 2 539 ? -30.309 -49.976 -100.650 1.00 90.34 ? 539 LYS D CE 1 +ATOM 13338 N NZ . LYS D 2 539 ? -30.115 -48.629 -101.262 1.00 94.12 ? 539 LYS D NZ 1 +ATOM 13339 N N . ASP D 2 540 ? -30.439 -52.587 -93.883 1.00 72.94 ? 540 ASP D N 1 +ATOM 13340 C CA . ASP D 2 540 ? -29.958 -52.644 -92.509 1.00 70.60 ? 540 ASP D CA 1 +ATOM 13341 C C . ASP D 2 540 ? -30.513 -53.815 -91.711 1.00 69.45 ? 540 ASP D C 1 +ATOM 13342 O O . ASP D 2 540 ? -29.985 -54.105 -90.629 1.00 60.72 ? 540 ASP D O 1 +ATOM 13343 C CB . ASP D 2 540 ? -30.290 -51.343 -91.762 1.00 76.96 ? 540 ASP D CB 1 +ATOM 13344 C CG . ASP D 2 540 ? -29.382 -50.198 -92.153 1.00 84.35 ? 540 ASP D CG 1 +ATOM 13345 O OD1 . ASP D 2 540 ? -28.199 -50.466 -92.453 1.00 92.71 ? 540 ASP D OD1 1 +ATOM 13346 O OD2 . ASP D 2 540 ? -29.841 -49.033 -92.141 1.00 73.19 ? 540 ASP D OD2 1 +ATOM 13347 N N . GLY D 2 541 ? -31.546 -54.488 -92.200 1.00 72.26 ? 541 GLY D N 1 +ATOM 13348 C CA . GLY D 2 541 ? -32.105 -55.642 -91.528 1.00 72.00 ? 541 GLY D CA 1 +ATOM 13349 C C . GLY D 2 541 ? -33.054 -55.267 -90.403 1.00 70.71 ? 541 GLY D C 1 +ATOM 13350 O O . GLY D 2 541 ? -32.992 -54.186 -89.822 1.00 79.18 ? 541 GLY D O 1 +ATOM 13351 N N . PHE D 2 542 ? -33.947 -56.200 -90.085 1.00 61.35 ? 542 PHE D N 1 +ATOM 13352 C CA . PHE D 2 542 ? -34.825 -56.026 -88.939 1.00 68.08 ? 542 PHE D CA 1 +ATOM 13353 C C . PHE D 2 542 ? -34.003 -56.037 -87.649 1.00 74.09 ? 542 PHE D C 1 +ATOM 13354 O O . PHE D 2 542 ? -32.780 -56.205 -87.656 1.00 76.75 ? 542 PHE D O 1 +ATOM 13355 C CB . PHE D 2 542 ? -35.892 -57.117 -88.916 1.00 73.02 ? 542 PHE D CB 1 +ATOM 13356 C CG . PHE D 2 542 ? -36.905 -56.996 -90.015 1.00 89.39 ? 542 PHE D CG 1 +ATOM 13357 C CD1 . PHE D 2 542 ? -36.632 -57.499 -91.283 1.00 103.71 ? 542 PHE D CD1 1 +ATOM 13358 C CD2 . PHE D 2 542 ? -38.135 -56.400 -89.783 1.00 75.23 ? 542 PHE D CD2 1 +ATOM 13359 C CE1 . PHE D 2 542 ? -37.562 -57.393 -92.308 1.00 94.90 ? 542 PHE D CE1 1 +ATOM 13360 C CE2 . PHE D 2 542 ? -39.071 -56.292 -90.804 1.00 94.34 ? 542 PHE D CE2 1 +ATOM 13361 C CZ . PHE D 2 542 ? -38.781 -56.790 -92.068 1.00 92.64 ? 542 PHE D CZ 1 +ATOM 13362 N N . SER D 2 543 ? -34.692 -55.805 -86.527 1.00 76.19 ? 543 SER D N 1 +ATOM 13363 C CA . SER D 2 543 ? -34.102 -55.747 -85.186 1.00 83.79 ? 543 SER D CA 1 +ATOM 13364 C C . SER D 2 543 ? -33.095 -54.607 -85.039 1.00 82.73 ? 543 SER D C 1 +ATOM 13365 O O . SER D 2 543 ? -32.949 -54.039 -83.949 1.00 71.91 ? 543 SER D O 1 +ATOM 13366 C CB . SER D 2 543 ? -33.453 -57.085 -84.818 1.00 87.19 ? 543 SER D CB 1 +ATOM 13367 O OG . SER D 2 543 ? -34.415 -58.128 -84.778 1.00 76.39 ? 543 SER D OG 1 +ATOM 13368 N N . ALA D 2 544 ? -32.403 -54.266 -86.126 1.00 87.56 ? 544 ALA D N 1 +ATOM 13369 C CA . ALA D 2 544 ? -31.553 -53.088 -86.206 1.00 92.19 ? 544 ALA D CA 1 +ATOM 13370 C C . ALA D 2 544 ? -32.252 -51.934 -86.910 1.00 82.05 ? 544 ALA D C 1 +ATOM 13371 O O . ALA D 2 544 ? -31.693 -50.834 -86.991 1.00 78.08 ? 544 ALA D O 1 +ATOM 13372 C CB . ALA D 2 544 ? -30.243 -53.423 -86.932 1.00 82.03 ? 544 ALA D CB 1 +ATOM 13373 N N . VAL D 2 545 ? -33.460 -52.164 -87.417 1.00 69.55 ? 545 VAL D N 1 +ATOM 13374 C CA . VAL D 2 545 ? -34.320 -51.105 -87.914 1.00 60.02 ? 545 VAL D CA 1 +ATOM 13375 C C . VAL D 2 545 ? -35.565 -50.959 -87.053 1.00 65.65 ? 545 VAL D C 1 +ATOM 13376 O O . VAL D 2 545 ? -35.998 -49.842 -86.766 1.00 71.18 ? 545 VAL D O 1 +ATOM 13377 C CB . VAL D 2 545 ? -34.698 -51.337 -89.393 1.00 58.53 ? 545 VAL D CB 1 +ATOM 13378 C CG1 . VAL D 2 545 ? -35.850 -50.443 -89.788 1.00 60.11 ? 545 VAL D CG1 1 +ATOM 13379 C CG2 . VAL D 2 545 ? -33.516 -51.045 -90.284 1.00 68.69 ? 545 VAL D CG2 1 +ATOM 13380 N N . VAL D 2 546 ? -36.141 -52.069 -86.607 1.00 71.51 ? 546 VAL D N 1 +ATOM 13381 C CA . VAL D 2 546 ? -37.294 -52.050 -85.717 1.00 71.52 ? 546 VAL D CA 1 +ATOM 13382 C C . VAL D 2 546 ? -36.827 -52.475 -84.329 1.00 72.71 ? 546 VAL D C 1 +ATOM 13383 O O . VAL D 2 546 ? -36.176 -53.516 -84.174 1.00 77.35 ? 546 VAL D O 1 +ATOM 13384 C CB . VAL D 2 546 ? -38.426 -52.947 -86.248 1.00 75.91 ? 546 VAL D CB 1 +ATOM 13385 C CG1 . VAL D 2 546 ? -39.129 -52.250 -87.406 1.00 61.63 ? 546 VAL D CG1 1 +ATOM 13386 C CG2 . VAL D 2 546 ? -37.883 -54.302 -86.714 1.00 79.08 ? 546 VAL D CG2 1 +ATOM 13387 N N . GLU D 2 547 ? -37.111 -51.650 -83.329 1.00 71.88 ? 547 GLU D N 1 +ATOM 13388 C CA . GLU D 2 547 ? -36.784 -51.975 -81.948 1.00 77.22 ? 547 GLU D CA 1 +ATOM 13389 C C . GLU D 2 547 ? -38.045 -52.476 -81.260 1.00 78.95 ? 547 GLU D C 1 +ATOM 13390 O O . GLU D 2 547 ? -39.061 -51.772 -81.231 1.00 75.44 ? 547 GLU D O 1 +ATOM 13391 C CB . GLU D 2 547 ? -36.204 -50.768 -81.216 1.00 73.56 ? 547 GLU D CB 1 +ATOM 13392 C CG . GLU D 2 547 ? -34.736 -50.535 -81.525 1.00 87.93 ? 547 GLU D CG 1 +ATOM 13393 C CD . GLU D 2 547 ? -34.078 -49.614 -80.524 1.00 100.25 ? 547 GLU D CD 1 +ATOM 13394 O OE1 . GLU D 2 547 ? -34.789 -48.751 -79.970 1.00 103.50 ? 547 GLU D OE1 1 +ATOM 13395 O OE2 . GLU D 2 547 ? -32.852 -49.740 -80.305 1.00 106.03 ? 547 GLU D OE2 1 +ATOM 13396 N N . ASN D 2 548 ? -37.990 -53.703 -80.743 1.00 78.75 ? 548 ASN D N 1 +ATOM 13397 C CA . ASN D 2 548 ? -39.148 -54.278 -80.073 1.00 75.75 ? 548 ASN D CA 1 +ATOM 13398 C C . ASN D 2 548 ? -39.550 -53.438 -78.870 1.00 71.39 ? 548 ASN D C 1 +ATOM 13399 O O . ASN D 2 548 ? -38.764 -53.242 -77.937 1.00 70.67 ? 548 ASN D O 1 +ATOM 13400 C CB . ASN D 2 548 ? -38.852 -55.713 -79.647 1.00 72.36 ? 548 ASN D CB 1 +ATOM 13401 C CG . ASN D 2 548 ? -40.093 -56.586 -79.646 1.00 70.91 ? 548 ASN D CG 1 +ATOM 13402 O OD1 . ASN D 2 548 ? -41.222 -56.089 -79.707 1.00 65.85 ? 548 ASN D OD1 1 +ATOM 13403 N ND2 . ASN D 2 548 ? -39.889 -57.895 -79.590 1.00 78.90 ? 548 ASN D ND2 1 +ATOM 13404 N N . ASP D 2 549 ? -40.793 -52.971 -78.886 1.00 67.91 ? 549 ASP D N 1 +ATOM 13405 C CA . ASP D 2 549 ? -41.400 -52.281 -77.762 1.00 67.59 ? 549 ASP D CA 1 +ATOM 13406 C C . ASP D 2 549 ? -42.604 -53.020 -77.202 1.00 67.62 ? 549 ASP D C 1 +ATOM 13407 O O . ASP D 2 549 ? -42.908 -52.858 -76.014 1.00 62.44 ? 549 ASP D O 1 +ATOM 13408 C CB . ASP D 2 549 ? -41.795 -50.842 -78.140 1.00 59.79 ? 549 ASP D CB 1 +ATOM 13409 C CG . ASP D 2 549 ? -42.712 -50.774 -79.335 1.00 55.94 ? 549 ASP D CG 1 +ATOM 13410 O OD1 . ASP D 2 549 ? -42.451 -51.462 -80.345 1.00 56.38 ? 549 ASP D OD1 1 +ATOM 13411 O OD2 . ASP D 2 549 ? -43.696 -50.017 -79.258 1.00 55.30 ? 549 ASP D OD2 1 +ATOM 13412 N N . LEU D 2 550 ? -43.276 -53.840 -78.015 1.00 65.42 ? 550 LEU D N 1 +ATOM 13413 C CA . LEU D 2 550 ? -44.504 -54.541 -77.662 1.00 63.36 ? 550 LEU D CA 1 +ATOM 13414 C C . LEU D 2 550 ? -44.286 -55.715 -76.713 1.00 68.64 ? 550 LEU D C 1 +ATOM 13415 O O . LEU D 2 550 ? -45.256 -56.413 -76.397 1.00 66.11 ? 550 LEU D O 1 +ATOM 13416 C CB . LEU D 2 550 ? -45.196 -55.044 -78.939 1.00 60.03 ? 550 LEU D CB 1 +ATOM 13417 C CG . LEU D 2 550 ? -46.304 -54.198 -79.583 1.00 58.05 ? 550 LEU D CG 1 +ATOM 13418 C CD1 . LEU D 2 550 ? -46.072 -52.718 -79.351 1.00 63.46 ? 550 LEU D CD1 1 +ATOM 13419 C CD2 . LEU D 2 550 ? -46.442 -54.487 -81.078 1.00 50.09 ? 550 LEU D CD2 1 +ATOM 13420 N N . ASP D 2 551 ? -43.063 -55.938 -76.232 1.00 72.03 ? 551 ASP D N 1 +ATOM 13421 C CA . ASP D 2 551 ? -42.831 -56.986 -75.244 1.00 67.79 ? 551 ASP D CA 1 +ATOM 13422 C C . ASP D 2 551 ? -43.596 -56.690 -73.963 1.00 62.76 ? 551 ASP D C 1 +ATOM 13423 O O . ASP D 2 551 ? -43.061 -56.060 -73.046 1.00 58.39 ? 551 ASP D O 1 +ATOM 13424 C CB . ASP D 2 551 ? -41.342 -57.133 -74.949 1.00 65.32 ? 551 ASP D CB 1 +ATOM 13425 C CG . ASP D 2 551 ? -40.574 -57.639 -76.144 1.00 77.96 ? 551 ASP D CG 1 +ATOM 13426 O OD1 . ASP D 2 551 ? -41.206 -58.249 -77.036 1.00 84.52 ? 551 ASP D OD1 1 +ATOM 13427 O OD2 . ASP D 2 551 ? -39.347 -57.418 -76.198 1.00 77.07 ? 551 ASP D OD2 1 +ATOM 13428 N N . GLY D 2 552 ? -44.847 -57.139 -73.904 1.00 62.09 ? 552 GLY D N 1 +ATOM 13429 C CA . GLY D 2 552 ? -45.702 -56.930 -72.752 1.00 51.25 ? 552 GLY D CA 1 +ATOM 13430 C C . GLY D 2 552 ? -47.164 -56.873 -73.147 1.00 48.35 ? 552 GLY D C 1 +ATOM 13431 O O . GLY D 2 552 ? -47.953 -57.740 -72.773 1.00 51.30 ? 552 GLY D O 1 +HETATM 13432 P PG . ATP E 3 . ? -63.590 -17.845 -48.220 1.00 84.39 ? 701 ATP A PG 1 +HETATM 13433 O O1G . ATP E 3 . ? -64.752 -18.587 -48.837 1.00 81.20 ? 701 ATP A O1G 1 +HETATM 13434 O O2G . ATP E 3 . ? -63.584 -17.796 -46.711 1.00 80.33 ? 701 ATP A O2G 1 +HETATM 13435 O O3G . ATP E 3 . ? -62.252 -18.208 -48.822 1.00 76.61 ? 701 ATP A O3G 1 +HETATM 13436 P PB . ATP E 3 . ? -62.842 -15.131 -48.613 1.00 93.11 ? 701 ATP A PB 1 +HETATM 13437 O O1B . ATP E 3 . ? -61.449 -15.703 -48.722 1.00 87.07 ? 701 ATP A O1B 1 +HETATM 13438 O O2B . ATP E 3 . ? -63.169 -14.155 -47.506 1.00 75.15 ? 701 ATP A O2B 1 +HETATM 13439 O O3B . ATP E 3 . ? -63.915 -16.328 -48.660 1.00 91.56 ? 701 ATP A O3B 1 +HETATM 13440 P PA . ATP E 3 . ? -62.110 -13.656 -50.833 1.00 99.03 ? 701 ATP A PA 1 +HETATM 13441 O O1A . ATP E 3 . ? -61.990 -14.324 -52.182 1.00 101.88 ? 701 ATP A O1A 1 +HETATM 13442 O O2A . ATP E 3 . ? -60.881 -13.498 -49.966 1.00 85.03 ? 701 ATP A O2A 1 +HETATM 13443 O O3A . ATP E 3 . ? -63.243 -14.410 -49.987 1.00 79.12 ? 701 ATP A O3A 1 +HETATM 13444 O "O5'" . ATP E 3 . ? -62.813 -12.217 -50.982 1.00 73.52 ? 701 ATP A "O5'" 1 +HETATM 13445 C "C5'" . ATP E 3 . ? -62.304 -11.121 -50.229 1.00 74.72 ? 701 ATP A "C5'" 1 +HETATM 13446 C "C4'" . ATP E 3 . ? -61.974 -9.941 -51.133 1.00 73.33 ? 701 ATP A "C4'" 1 +HETATM 13447 O "O4'" . ATP E 3 . ? -62.143 -8.747 -50.368 1.00 68.96 ? 701 ATP A "O4'" 1 +HETATM 13448 C "C3'" . ATP E 3 . ? -60.529 -9.967 -51.626 1.00 65.43 ? 701 ATP A "C3'" 1 +HETATM 13449 O "O3'" . ATP E 3 . ? -60.433 -10.252 -53.028 1.00 53.27 ? 701 ATP A "O3'" 1 +HETATM 13450 C "C2'" . ATP E 3 . ? -59.990 -8.577 -51.358 1.00 65.72 ? 701 ATP A "C2'" 1 +HETATM 13451 O "O2'" . ATP E 3 . ? -59.710 -7.926 -52.601 1.00 71.04 ? 701 ATP A "O2'" 1 +HETATM 13452 C "C1'" . ATP E 3 . ? -61.092 -7.820 -50.638 1.00 67.31 ? 701 ATP A "C1'" 1 +HETATM 13453 N N9 . ATP E 3 . ? -60.599 -7.249 -49.360 1.00 57.41 ? 701 ATP A N9 1 +HETATM 13454 C C8 . ATP E 3 . ? -60.900 -7.701 -48.131 1.00 50.96 ? 701 ATP A C8 1 +HETATM 13455 N N7 . ATP E 3 . ? -60.297 -6.947 -47.177 1.00 49.12 ? 701 ATP A N7 1 +HETATM 13456 C C5 . ATP E 3 . ? -59.595 -5.988 -47.805 1.00 51.61 ? 701 ATP A C5 1 +HETATM 13457 C C6 . ATP E 3 . ? -58.725 -4.857 -47.401 1.00 58.23 ? 701 ATP A C6 1 +HETATM 13458 N N6 . ATP E 3 . ? -58.477 -4.596 -46.097 1.00 52.25 ? 701 ATP A N6 1 +HETATM 13459 N N1 . ATP E 3 . ? -58.187 -4.088 -48.376 1.00 66.11 ? 701 ATP A N1 1 +HETATM 13460 C C2 . ATP E 3 . ? -58.422 -4.336 -49.680 1.00 66.69 ? 701 ATP A C2 1 +HETATM 13461 N N3 . ATP E 3 . ? -59.197 -5.346 -50.115 1.00 66.53 ? 701 ATP A N3 1 +HETATM 13462 C C4 . ATP E 3 . ? -59.802 -6.190 -49.244 1.00 57.66 ? 701 ATP A C4 1 +HETATM 13463 P PG . ATP F 3 . ? -34.768 13.088 -117.524 1.00 75.24 ? 701 ATP B PG 1 +HETATM 13464 O O1G . ATP F 3 . ? -34.668 13.025 -119.030 1.00 69.81 ? 701 ATP B O1G 1 +HETATM 13465 O O2G . ATP F 3 . ? -34.280 14.367 -116.879 1.00 58.38 ? 701 ATP B O2G 1 +HETATM 13466 O O3G . ATP F 3 . ? -34.268 11.836 -116.844 1.00 78.18 ? 701 ATP B O3G 1 +HETATM 13467 P PB . ATP F 3 . ? -37.326 11.876 -117.180 1.00 74.16 ? 701 ATP B PB 1 +HETATM 13468 O O1B . ATP F 3 . ? -38.498 12.045 -118.110 1.00 68.91 ? 701 ATP B O1B 1 +HETATM 13469 O O2B . ATP F 3 . ? -36.536 10.587 -117.223 1.00 64.75 ? 701 ATP B O2B 1 +HETATM 13470 O O3B . ATP F 3 . ? -36.354 13.157 -117.246 1.00 77.50 ? 701 ATP B O3B 1 +HETATM 13471 P PA . ATP F 3 . ? -38.666 10.998 -114.936 1.00 82.59 ? 701 ATP B PA 1 +HETATM 13472 O O1A . ATP F 3 . ? -38.595 9.759 -115.792 1.00 75.64 ? 701 ATP B O1A 1 +HETATM 13473 O O2A . ATP F 3 . ? -38.138 11.001 -113.521 1.00 88.28 ? 701 ATP B O2A 1 +HETATM 13474 O O3A . ATP F 3 . ? -37.928 12.172 -115.726 1.00 69.61 ? 701 ATP B O3A 1 +HETATM 13475 O "O5'" . ATP F 3 . ? -40.190 11.507 -114.980 1.00 64.31 ? 701 ATP B "O5'" 1 +HETATM 13476 C "C5'" . ATP F 3 . ? -41.170 10.681 -115.603 1.00 62.18 ? 701 ATP B "C5'" 1 +HETATM 13477 C "C4'" . ATP F 3 . ? -42.344 10.452 -114.663 1.00 61.08 ? 701 ATP B "C4'" 1 +HETATM 13478 O "O4'" . ATP F 3 . ? -43.533 10.365 -115.444 1.00 61.39 ? 701 ATP B "O4'" 1 +HETATM 13479 C "C3'" . ATP F 3 . ? -42.196 9.151 -113.886 1.00 58.94 ? 701 ATP B "C3'" 1 +HETATM 13480 O "O3'" . ATP F 3 . ? -42.199 9.406 -112.477 1.00 54.69 ? 701 ATP B "O3'" 1 +HETATM 13481 C "C2'" . ATP F 3 . ? -43.404 8.314 -114.249 1.00 60.97 ? 701 ATP B "C2'" 1 +HETATM 13482 O "O2'" . ATP F 3 . ? -44.097 7.923 -113.061 1.00 69.04 ? 701 ATP B "O2'" 1 +HETATM 13483 C "C1'" . ATP F 3 . ? -44.297 9.220 -115.078 1.00 59.58 ? 701 ATP B "C1'" 1 +HETATM 13484 N N9 . ATP F 3 . ? -44.742 8.541 -116.313 1.00 54.38 ? 701 ATP B N9 1 +HETATM 13485 C C8 . ATP F 3 . ? -44.233 8.727 -117.544 1.00 49.61 ? 701 ATP B C8 1 +HETATM 13486 N N7 . ATP F 3 . ? -44.878 7.957 -118.454 1.00 45.20 ? 701 ATP B N7 1 +HETATM 13487 C C5 . ATP F 3 . ? -45.824 7.264 -117.795 1.00 49.94 ? 701 ATP B C5 1 +HETATM 13488 C C6 . ATP F 3 . ? -46.863 6.269 -118.146 1.00 57.59 ? 701 ATP B C6 1 +HETATM 13489 N N6 . ATP F 3 . ? -47.028 5.843 -119.423 1.00 55.38 ? 701 ATP B N6 1 +HETATM 13490 N N1 . ATP F 3 . ? -47.644 5.798 -117.146 1.00 63.74 ? 701 ATP B N1 1 +HETATM 13491 C C2 . ATP F 3 . ? -47.496 6.208 -115.871 1.00 61.29 ? 701 ATP B C2 1 +HETATM 13492 N N3 . ATP F 3 . ? -46.576 7.107 -115.483 1.00 58.09 ? 701 ATP B N3 1 +HETATM 13493 C C4 . ATP F 3 . ? -45.730 7.658 -116.383 1.00 53.07 ? 701 ATP B C4 1 +# +loop_ +_pdbx_poly_seq_scheme.asym_id +_pdbx_poly_seq_scheme.entity_id +_pdbx_poly_seq_scheme.seq_id +_pdbx_poly_seq_scheme.mon_id +_pdbx_poly_seq_scheme.ndb_seq_num +_pdbx_poly_seq_scheme.pdb_seq_num +_pdbx_poly_seq_scheme.auth_seq_num +_pdbx_poly_seq_scheme.pdb_mon_id +_pdbx_poly_seq_scheme.auth_mon_id +_pdbx_poly_seq_scheme.pdb_strand_id +_pdbx_poly_seq_scheme.pdb_ins_code +_pdbx_poly_seq_scheme.hetero +A 1 1 ASP 1 63 ? ? ? A . n +A 1 2 PRO 2 64 ? ? ? A . n +A 1 3 GLY 3 65 ? ? ? A . n +A 1 4 THR 4 66 ? ? ? A . n +A 1 5 ILE 5 67 ? ? ? A . n +A 1 6 VAL 6 68 ? ? ? A . n +A 1 7 HIS 7 69 ? ? ? A . n +A 1 8 ASN 8 70 ? ? ? A . n +A 1 9 PHE 9 71 ? ? ? A . n +A 1 10 SER 10 72 ? ? ? A . n +A 1 11 ARG 11 73 ? ? ? A . n +A 1 12 THR 12 74 ? ? ? A . n +A 1 13 GLU 13 75 ? ? ? A . n +A 1 14 PRO 14 76 ? ? ? A . n +A 1 15 ARG 15 77 ? ? ? A . n +A 1 16 THR 16 78 ? ? ? A . n +A 1 17 GLU 17 79 ? ? ? A . n +A 1 18 PRO 18 80 ? ? ? A . n +A 1 19 ALA 19 81 ? ? ? A . n +A 1 20 GLY 20 82 ? ? ? A . n +A 1 21 GLY 21 83 ? ? ? A . n +A 1 22 SER 22 84 ? ? ? A . n +A 1 23 HIS 23 85 ? ? ? A . n +A 1 24 SER 24 86 ? ? ? A . n +A 1 25 GLY 25 87 ? ? ? A . n +A 1 26 SER 26 88 ? ? ? A . n +A 1 27 SER 27 89 89 SER SER A . n +A 1 28 SER 28 90 90 SER SER A . n +A 1 29 LYS 29 91 91 LYS LYS A . n +A 1 30 LEU 30 92 92 LEU LEU A . n +A 1 31 GLN 31 93 93 GLN GLN A . n +A 1 32 ALA 32 94 94 ALA ALA A . n +A 1 33 LEU 33 95 95 LEU LEU A . n +A 1 34 PHE 34 96 96 PHE PHE A . n +A 1 35 ALA 35 97 97 ALA ALA A . n +A 1 36 HIS 36 98 98 HIS HIS A . n +A 1 37 PRO 37 99 99 PRO PRO A . n +A 1 38 LEU 38 100 100 LEU LEU A . n +A 1 39 TYR 39 101 101 TYR TYR A . n +A 1 40 ASN 40 102 102 ASN ASN A . n +A 1 41 VAL 41 103 103 VAL VAL A . n +A 1 42 PRO 42 104 104 PRO PRO A . n +A 1 43 GLU 43 105 105 GLU GLU A . n +A 1 44 GLU 44 106 106 GLU GLU A . n +A 1 45 PRO 45 107 107 PRO PRO A . n +A 1 46 PRO 46 108 108 PRO PRO A . n +A 1 47 LEU 47 109 109 LEU LEU A . n +A 1 48 LEU 48 110 110 LEU LEU A . n +A 1 49 GLY 49 111 111 GLY GLY A . n +A 1 50 ALA 50 112 112 ALA ALA A . n +A 1 51 GLU 51 113 113 GLU GLU A . n +A 1 52 ASP 52 114 114 ASP ASP A . n +A 1 53 SER 53 115 115 SER SER A . n +A 1 54 LEU 54 116 116 LEU LEU A . n +A 1 55 LEU 55 117 117 LEU LEU A . n +A 1 56 ALA 56 118 118 ALA ALA A . n +A 1 57 SER 57 119 119 SER SER A . n +A 1 58 GLN 58 120 120 GLN GLN A . n +A 1 59 GLU 59 121 121 GLU GLU A . n +A 1 60 ALA 60 122 122 ALA ALA A . n +A 1 61 LEU 61 123 123 LEU LEU A . n +A 1 62 ARG 62 124 124 ARG ARG A . n +A 1 63 TYR 63 125 125 TYR TYR A . n +A 1 64 TYR 64 126 126 TYR TYR A . n +A 1 65 ARG 65 127 127 ARG ARG A . n +A 1 66 ARG 66 128 128 ARG ARG A . n +A 1 67 LYS 67 129 129 LYS LYS A . n +A 1 68 VAL 68 130 130 VAL VAL A . n +A 1 69 ALA 69 131 131 ALA ALA A . n +A 1 70 ARG 70 132 132 ARG ARG A . n +A 1 71 TRP 71 133 133 TRP TRP A . n +A 1 72 ASN 72 134 134 ASN ASN A . n +A 1 73 ARG 73 135 135 ARG ARG A . n +A 1 74 ARG 74 136 136 ARG ARG A . n +A 1 75 HIS 75 137 137 HIS HIS A . n +A 1 76 LYS 76 138 138 LYS LYS A . n +A 1 77 MET 77 139 139 MET MET A . n +A 1 78 TYR 78 140 ? ? ? A . n +A 1 79 ARG 79 141 ? ? ? A . n +A 1 80 GLU 80 142 ? ? ? A . n +A 1 81 GLN 81 143 ? ? ? A . n +A 1 82 MET 82 144 ? ? ? A . n +A 1 83 ASN 83 145 ? ? ? A . n +A 1 84 LEU 84 146 ? ? ? A . n +A 1 85 THR 85 147 ? ? ? A . n +A 1 86 SER 86 148 ? ? ? A . n +A 1 87 LEU 87 149 ? ? ? A . n +A 1 88 ASP 88 150 150 ASP ASP A . n +A 1 89 PRO 89 151 151 PRO PRO A . n +A 1 90 PRO 90 152 152 PRO PRO A . n +A 1 91 LEU 91 153 153 LEU LEU A . n +A 1 92 GLN 92 154 154 GLN GLN A . n +A 1 93 LEU 93 155 155 LEU LEU A . n +A 1 94 ARG 94 156 156 ARG ARG A . n +A 1 95 LEU 95 157 157 LEU LEU A . n +A 1 96 GLU 96 158 158 GLU GLU A . n +A 1 97 ALA 97 159 159 ALA ALA A . n +A 1 98 SER 98 160 160 SER SER A . n +A 1 99 TRP 99 161 161 TRP TRP A . n +A 1 100 VAL 100 162 162 VAL VAL A . n +A 1 101 GLN 101 163 163 GLN GLN A . n +A 1 102 PHE 102 164 164 PHE PHE A . n +A 1 103 HIS 103 165 165 HIS HIS A . n +A 1 104 LEU 104 166 166 LEU LEU A . n +A 1 105 GLY 105 167 167 GLY GLY A . n +A 1 106 ILE 106 168 168 ILE ILE A . n +A 1 107 ASN 107 169 169 ASN ASN A . n +A 1 108 ARG 108 170 170 ARG ARG A . n +A 1 109 HIS 109 171 171 HIS HIS A . n +A 1 110 GLY 110 172 172 GLY GLY A . n +A 1 111 LEU 111 173 173 LEU LEU A . n +A 1 112 TYR 112 174 174 TYR TYR A . n +A 1 113 SER 113 175 175 SER SER A . n +A 1 114 ARG 114 176 176 ARG ARG A . n +A 1 115 SER 115 177 177 SER SER A . n +A 1 116 SER 116 178 178 SER SER A . n +A 1 117 PRO 117 179 179 PRO PRO A . n +A 1 118 VAL 118 180 180 VAL VAL A . n +A 1 119 VAL 119 181 181 VAL VAL A . n +A 1 120 SER 120 182 182 SER SER A . n +A 1 121 LYS 121 183 183 LYS LYS A . n +A 1 122 LEU 122 184 184 LEU LEU A . n +A 1 123 LEU 123 185 185 LEU LEU A . n +A 1 124 GLN 124 186 186 GLN GLN A . n +A 1 125 ASP 125 187 187 ASP ASP A . n +A 1 126 MET 126 188 188 MET MET A . n +A 1 127 ARG 127 189 189 ARG ARG A . n +A 1 128 HIS 128 190 190 HIS HIS A . n +A 1 129 PHE 129 191 191 PHE PHE A . n +A 1 130 PRO 130 192 192 PRO PRO A . n +A 1 131 THR 131 193 193 THR THR A . n +A 1 132 ILE 132 194 194 ILE ILE A . n +A 1 133 SER 133 195 195 SER SER A . n +A 1 134 ALA 134 196 196 ALA ALA A . n +A 1 135 ASP 135 197 197 ASP ASP A . n +A 1 136 TYR 136 198 198 TYR TYR A . n +A 1 137 SER 137 199 199 SER SER A . n +A 1 138 GLN 138 200 200 GLN GLN A . n +A 1 139 ASP 139 201 201 ASP ASP A . n +A 1 140 GLU 140 202 202 GLU GLU A . n +A 1 141 LYS 141 203 203 LYS LYS A . n +A 1 142 ALA 142 204 204 ALA ALA A . n +A 1 143 LEU 143 205 205 LEU LEU A . n +A 1 144 LEU 144 206 206 LEU LEU A . n +A 1 145 GLY 145 207 207 GLY GLY A . n +A 1 146 ALA 146 208 208 ALA ALA A . n +A 1 147 CYS 147 209 209 CYS CYS A . n +A 1 148 ASP 148 210 210 ASP ASP A . n +A 1 149 CYS 149 211 211 CYS CYS A . n +A 1 150 THR 150 212 212 THR THR A . n +A 1 151 GLN 151 213 213 GLN GLN A . n +A 1 152 ILE 152 214 214 ILE ILE A . n +A 1 153 VAL 153 215 215 VAL VAL A . n +A 1 154 LYS 154 216 216 LYS LYS A . n +A 1 155 PRO 155 217 217 PRO PRO A . n +A 1 156 SER 156 218 218 SER SER A . n +A 1 157 GLY 157 219 219 GLY GLY A . n +A 1 158 VAL 158 220 220 VAL VAL A . n +A 1 159 HIS 159 221 221 HIS HIS A . n +A 1 160 LEU 160 222 222 LEU LEU A . n +A 1 161 LYS 161 223 223 LYS LYS A . n +A 1 162 LEU 162 224 224 LEU LEU A . n +A 1 163 VAL 163 225 225 VAL VAL A . n +A 1 164 LEU 164 226 226 LEU LEU A . n +A 1 165 ARG 165 227 227 ARG ARG A . n +A 1 166 PHE 166 228 228 PHE PHE A . n +A 1 167 SER 167 229 229 SER SER A . n +A 1 168 ASP 168 230 230 ASP ASP A . n +A 1 169 PHE 169 231 231 PHE PHE A . n +A 1 170 GLY 170 232 232 GLY GLY A . n +A 1 171 LYS 171 233 233 LYS LYS A . n +A 1 172 ALA 172 234 234 ALA ALA A . n +A 1 173 MET 173 235 235 MET MET A . n +A 1 174 PHE 174 236 236 PHE PHE A . n +A 1 175 LYS 175 237 237 LYS LYS A . n +A 1 176 PRO 176 238 238 PRO PRO A . n +A 1 177 MET 177 239 239 MET MET A . n +A 1 178 ARG 178 240 240 ARG ARG A . n +A 1 179 GLN 179 241 241 GLN GLN A . n +A 1 180 GLN 180 242 242 GLN GLN A . n +A 1 181 ARG 181 243 243 ARG ARG A . n +A 1 182 ASP 182 244 244 ASP ASP A . n +A 1 183 GLU 183 245 245 GLU GLU A . n +A 1 184 GLU 184 246 246 GLU GLU A . n +A 1 185 THR 185 247 247 THR THR A . n +A 1 186 PRO 186 248 248 PRO PRO A . n +A 1 187 VAL 187 249 249 VAL VAL A . n +A 1 188 ASP 188 250 250 ASP ASP A . n +A 1 189 PHE 189 251 251 PHE PHE A . n +A 1 190 PHE 190 252 252 PHE PHE A . n +A 1 191 TYR 191 253 253 TYR TYR A . n +A 1 192 PHE 192 254 254 PHE PHE A . n +A 1 193 ILE 193 255 255 ILE ILE A . n +A 1 194 ASP 194 256 256 ASP ASP A . n +A 1 195 PHE 195 257 257 PHE PHE A . n +A 1 196 GLN 196 258 258 GLN GLN A . n +A 1 197 ARG 197 259 259 ARG ARG A . n +A 1 198 HIS 198 260 260 HIS HIS A . n +A 1 199 ASN 199 261 261 ASN ASN A . n +A 1 200 ALA 200 262 262 ALA ALA A . n +A 1 201 GLU 201 263 263 GLU GLU A . n +A 1 202 ILE 202 264 264 ILE ILE A . n +A 1 203 ALA 203 265 265 ALA ALA A . n +A 1 204 ALA 204 266 266 ALA ALA A . n +A 1 205 PHE 205 267 267 PHE PHE A . n +A 1 206 HIS 206 268 268 HIS HIS A . n +A 1 207 LEU 207 269 269 LEU LEU A . n +A 1 208 ASP 208 270 270 ASP ASP A . n +A 1 209 ARG 209 271 271 ARG ARG A . n +A 1 210 ILE 210 272 272 ILE ILE A . n +A 1 211 LEU 211 273 273 LEU LEU A . n +A 1 212 ASP 212 274 274 ASP ASP A . n +A 1 213 PHE 213 275 275 PHE PHE A . n +A 1 214 ARG 214 276 276 ARG ARG A . n +A 1 215 ARG 215 277 277 ARG ARG A . n +A 1 216 VAL 216 278 278 VAL VAL A . n +A 1 217 PRO 217 279 279 PRO PRO A . n +A 1 218 PRO 218 280 280 PRO PRO A . n +A 1 219 THR 219 281 281 THR THR A . n +A 1 220 VAL 220 282 282 VAL VAL A . n +A 1 221 GLY 221 283 283 GLY GLY A . n +A 1 222 ARG 222 284 284 ARG ARG A . n +A 1 223 ILE 223 285 285 ILE ILE A . n +A 1 224 VAL 224 286 286 VAL VAL A . n +A 1 225 ASN 225 287 287 ASN ASN A . n +A 1 226 VAL 226 288 288 VAL VAL A . n +A 1 227 THR 227 289 289 THR THR A . n +A 1 228 LYS 228 290 290 LYS LYS A . n +A 1 229 GLU 229 291 291 GLU GLU A . n +A 1 230 ILE 230 292 292 ILE ILE A . n +A 1 231 LEU 231 293 293 LEU LEU A . n +A 1 232 GLU 232 294 294 GLU GLU A . n +A 1 233 VAL 233 295 295 VAL VAL A . n +A 1 234 THR 234 296 296 THR THR A . n +A 1 235 LYS 235 297 297 LYS LYS A . n +A 1 236 ASN 236 298 298 ASN ASN A . n +A 1 237 GLU 237 299 299 GLU GLU A . n +A 1 238 ILE 238 300 300 ILE ILE A . n +A 1 239 LEU 239 301 301 LEU LEU A . n +A 1 240 GLN 240 302 302 GLN GLN A . n +A 1 241 SER 241 303 303 SER SER A . n +A 1 242 VAL 242 304 304 VAL VAL A . n +A 1 243 PHE 243 305 305 PHE PHE A . n +A 1 244 PHE 244 306 306 PHE PHE A . n +A 1 245 VAL 245 307 307 VAL VAL A . n +A 1 246 SER 246 308 308 SER SER A . n +A 1 247 PRO 247 309 309 PRO PRO A . n +A 1 248 ALA 248 310 310 ALA ALA A . n +A 1 249 SER 249 311 311 SER SER A . n +A 1 250 ASN 250 312 312 ASN ASN A . n +A 1 251 VAL 251 313 313 VAL VAL A . n +A 1 252 CYS 252 314 314 CYS CYS A . n +A 1 253 PHE 253 315 315 PHE PHE A . n +A 1 254 PHE 254 316 316 PHE PHE A . n +A 1 255 ALA 255 317 317 ALA ALA A . n +A 1 256 LYS 256 318 318 LYS LYS A . n +A 1 257 CYS 257 319 319 CYS CYS A . n +A 1 258 PRO 258 320 320 PRO PRO A . n +A 1 259 TYR 259 321 321 TYR TYR A . n +A 1 260 MET 260 322 322 MET MET A . n +A 1 261 CYS 261 323 323 CYS CYS A . n +A 1 262 LYS 262 324 324 LYS LYS A . n +A 1 263 THR 263 325 325 THR THR A . n +A 1 264 GLU 264 326 326 GLU GLU A . n +A 1 265 TYR 265 327 327 TYR TYR A . n +A 1 266 ALA 266 328 328 ALA ALA A . n +A 1 267 VAL 267 329 329 VAL VAL A . n +A 1 268 CYS 268 330 330 CYS CYS A . n +A 1 269 GLY 269 331 331 GLY GLY A . n +A 1 270 LYS 270 332 332 LYS LYS A . n +A 1 271 PRO 271 333 333 PRO PRO A . n +A 1 272 HIS 272 334 334 HIS HIS A . n +A 1 273 LEU 273 335 335 LEU LEU A . n +A 1 274 LEU 274 336 336 LEU LEU A . n +A 1 275 GLU 275 337 337 GLU GLU A . n +A 1 276 GLY 276 338 338 GLY GLY A . n +A 1 277 SER 277 339 339 SER SER A . n +A 1 278 LEU 278 340 340 LEU LEU A . n +A 1 279 SER 279 341 341 SER SER A . n +A 1 280 ALA 280 342 342 ALA ALA A . n +A 1 281 PHE 281 343 343 PHE PHE A . n +A 1 282 LEU 282 344 344 LEU LEU A . n +A 1 283 PRO 283 345 345 PRO PRO A . n +A 1 284 SER 284 346 346 SER SER A . n +A 1 285 LEU 285 347 347 LEU LEU A . n +A 1 286 ASN 286 348 348 ASN ASN A . n +A 1 287 LEU 287 349 349 LEU LEU A . n +A 1 288 ALA 288 350 350 ALA ALA A . n +A 1 289 PRO 289 351 351 PRO PRO A . n +A 1 290 ARG 290 352 352 ARG ARG A . n +A 1 291 LEU 291 353 353 LEU LEU A . n +A 1 292 SER 292 354 354 SER SER A . n +A 1 293 VAL 293 355 355 VAL VAL A . n +A 1 294 PRO 294 356 356 PRO PRO A . n +A 1 295 ASN 295 357 357 ASN ASN A . n +A 1 296 PRO 296 358 358 PRO PRO A . n +A 1 297 TRP 297 359 359 TRP TRP A . n +A 1 298 ILE 298 360 360 ILE ILE A . n +A 1 299 ARG 299 361 361 ARG ARG A . n +A 1 300 SER 300 362 362 SER SER A . n +A 1 301 TYR 301 363 363 TYR TYR A . n +A 1 302 THR 302 364 364 THR THR A . n +A 1 303 LEU 303 365 365 LEU LEU A . n +A 1 304 ALA 304 366 366 ALA ALA A . n +A 1 305 GLY 305 367 367 GLY GLY A . n +A 1 306 LYS 306 368 368 LYS LYS A . n +A 1 307 GLU 307 369 369 GLU GLU A . n +A 1 308 GLU 308 370 370 GLU GLU A . n +A 1 309 TRP 309 371 371 TRP TRP A . n +A 1 310 GLU 310 372 372 GLU GLU A . n +A 1 311 VAL 311 373 373 VAL VAL A . n +A 1 312 ASN 312 374 374 ASN ASN A . n +A 1 313 PRO 313 375 375 PRO PRO A . n +A 1 314 LEU 314 376 376 LEU LEU A . n +A 1 315 TYR 315 377 377 TYR TYR A . n +A 1 316 CYS 316 378 378 CYS CYS A . n +A 1 317 ASP 317 379 379 ASP ASP A . n +A 1 318 THR 318 380 380 THR THR A . n +A 1 319 VAL 319 381 381 VAL VAL A . n +A 1 320 LYS 320 382 382 LYS LYS A . n +A 1 321 GLN 321 383 383 GLN GLN A . n +A 1 322 ILE 322 384 384 ILE ILE A . n +A 1 323 TYR 323 385 385 TYR TYR A . n +A 1 324 PRO 324 386 386 PRO PRO A . n +A 1 325 TYR 325 387 387 TYR TYR A . n +A 1 326 ASN 326 388 388 ASN ASN A . n +A 1 327 ASN 327 389 389 ASN ASN A . n +A 1 328 SER 328 390 390 SER SER A . n +A 1 329 GLN 329 391 391 GLN GLN A . n +A 1 330 ARG 330 392 392 ARG ARG A . n +A 1 331 LEU 331 393 393 LEU LEU A . n +A 1 332 LEU 332 394 394 LEU LEU A . n +A 1 333 ASN 333 395 395 ASN ASN A . n +A 1 334 VAL 334 396 396 VAL VAL A . n +A 1 335 ILE 335 397 397 ILE ILE A . n +A 1 336 ASP 336 398 398 ASP ASP A . n +A 1 337 MET 337 399 399 MET MET A . n +A 1 338 ALA 338 400 400 ALA ALA A . n +A 1 339 ILE 339 401 401 ILE ILE A . n +A 1 340 PHE 340 402 402 PHE PHE A . n +A 1 341 ASP 341 403 403 ASP ASP A . n +A 1 342 PHE 342 404 404 PHE PHE A . n +A 1 343 LEU 343 405 405 LEU LEU A . n +A 1 344 ILE 344 406 406 ILE ILE A . n +A 1 345 GLY 345 407 407 GLY GLY A . n +A 1 346 ASN 346 408 408 ASN ASN A . n +A 1 347 MET 347 409 409 MET MET A . n +A 1 348 ASP 348 410 410 ASP ASP A . n +A 1 349 ARG 349 411 411 ARG ARG A . n +A 1 350 HIS 350 412 412 HIS HIS A . n +A 1 351 HIS 351 413 413 HIS HIS A . n +A 1 352 TYR 352 414 414 TYR TYR A . n +A 1 353 GLU 353 415 415 GLU GLU A . n +A 1 354 MET 354 416 416 MET MET A . n +A 1 355 PHE 355 417 417 PHE PHE A . n +A 1 356 THR 356 418 418 THR THR A . n +A 1 357 LYS 357 419 419 LYS LYS A . n +A 1 358 PHE 358 420 420 PHE PHE A . n +A 1 359 GLY 359 421 421 GLY GLY A . n +A 1 360 ASP 360 422 422 ASP ASP A . n +A 1 361 ASP 361 423 423 ASP ASP A . n +A 1 362 GLY 362 424 424 GLY GLY A . n +A 1 363 PHE 363 425 425 PHE PHE A . n +A 1 364 LEU 364 426 426 LEU LEU A . n +A 1 365 ILE 365 427 427 ILE ILE A . n +A 1 366 HIS 366 428 428 HIS HIS A . n +A 1 367 LEU 367 429 429 LEU LEU A . n +A 1 368 ASP 368 430 430 ASP ASP A . n +A 1 369 ASN 369 431 431 ASN ASN A . n +A 1 370 ALA 370 432 432 ALA ALA A . n +A 1 371 ARG 371 433 433 ARG ARG A . n +A 1 372 GLY 372 434 434 GLY GLY A . n +A 1 373 PHE 373 435 435 PHE PHE A . n +A 1 374 GLY 374 436 436 GLY GLY A . n +A 1 375 ARG 375 437 437 ARG ARG A . n +A 1 376 HIS 376 438 438 HIS HIS A . n +A 1 377 SER 377 439 439 SER SER A . n +A 1 378 HIS 378 440 440 HIS HIS A . n +A 1 379 ASP 379 441 441 ASP ASP A . n +A 1 380 GLU 380 442 442 GLU GLU A . n +A 1 381 ILE 381 443 443 ILE ILE A . n +A 1 382 SER 382 444 444 SER SER A . n +A 1 383 ILE 383 445 445 ILE ILE A . n +A 1 384 LEU 384 446 446 LEU LEU A . n +A 1 385 SER 385 447 447 SER SER A . n +A 1 386 PRO 386 448 448 PRO PRO A . n +A 1 387 LEU 387 449 449 LEU LEU A . n +A 1 388 SER 388 450 450 SER SER A . n +A 1 389 GLN 389 451 451 GLN GLN A . n +A 1 390 CYS 390 452 452 CYS CYS A . n +A 1 391 CYS 391 453 453 CYS CYS A . n +A 1 392 MET 392 454 454 MET MET A . n +A 1 393 ILE 393 455 455 ILE ILE A . n +A 1 394 LYS 394 456 456 LYS LYS A . n +A 1 395 LYS 395 457 457 LYS LYS A . n +A 1 396 LYS 396 458 458 LYS LYS A . n +A 1 397 THR 397 459 459 THR THR A . n +A 1 398 LEU 398 460 460 LEU LEU A . n +A 1 399 LEU 399 461 461 LEU LEU A . n +A 1 400 HIS 400 462 462 HIS HIS A . n +A 1 401 LEU 401 463 463 LEU LEU A . n +A 1 402 GLN 402 464 464 GLN GLN A . n +A 1 403 LEU 403 465 465 LEU LEU A . n +A 1 404 LEU 404 466 466 LEU LEU A . n +A 1 405 ALA 405 467 467 ALA ALA A . n +A 1 406 GLN 406 468 468 GLN GLN A . n +A 1 407 ALA 407 469 469 ALA ALA A . n +A 1 408 ASP 408 470 470 ASP ASP A . n +A 1 409 TYR 409 471 471 TYR TYR A . n +A 1 410 ARG 410 472 472 ARG ARG A . n +A 1 411 LEU 411 473 473 LEU LEU A . n +A 1 412 SER 412 474 474 SER SER A . n +A 1 413 ASP 413 475 475 ASP ASP A . n +A 1 414 VAL 414 476 476 VAL VAL A . n +A 1 415 MET 415 477 477 MET MET A . n +A 1 416 ARG 416 478 478 ARG ARG A . n +A 1 417 GLU 417 479 479 GLU GLU A . n +A 1 418 SER 418 480 480 SER SER A . n +A 1 419 LEU 419 481 481 LEU LEU A . n +A 1 420 LEU 420 482 482 LEU LEU A . n +A 1 421 GLU 421 483 483 GLU GLU A . n +A 1 422 ASP 422 484 484 ASP ASP A . n +A 1 423 GLN 423 485 485 GLN GLN A . n +A 1 424 LEU 424 486 486 LEU LEU A . n +A 1 425 SER 425 487 487 SER SER A . n +A 1 426 PRO 426 488 488 PRO PRO A . n +A 1 427 VAL 427 489 489 VAL VAL A . n +A 1 428 LEU 428 490 490 LEU LEU A . n +A 1 429 THR 429 491 491 THR THR A . n +A 1 430 GLU 430 492 492 GLU GLU A . n +A 1 431 PRO 431 493 493 PRO PRO A . n +A 1 432 HIS 432 494 494 HIS HIS A . n +A 1 433 LEU 433 495 495 LEU LEU A . n +A 1 434 LEU 434 496 496 LEU LEU A . n +A 1 435 ALA 435 497 497 ALA ALA A . n +A 1 436 LEU 436 498 498 LEU LEU A . n +A 1 437 ASP 437 499 499 ASP ASP A . n +A 1 438 ARG 438 500 500 ARG ARG A . n +A 1 439 ARG 439 501 501 ARG ARG A . n +A 1 440 LEU 440 502 502 LEU LEU A . n +A 1 441 GLN 441 503 503 GLN GLN A . n +A 1 442 THR 442 504 504 THR THR A . n +A 1 443 ILE 443 505 505 ILE ILE A . n +A 1 444 LEU 444 506 506 LEU LEU A . n +A 1 445 ARG 445 507 507 ARG ARG A . n +A 1 446 THR 446 508 508 THR THR A . n +A 1 447 VAL 447 509 509 VAL VAL A . n +A 1 448 GLU 448 510 510 GLU GLU A . n +A 1 449 GLY 449 511 511 GLY GLY A . n +A 1 450 CYS 450 512 512 CYS CYS A . n +A 1 451 ILE 451 513 513 ILE ILE A . n +A 1 452 VAL 452 514 514 VAL VAL A . n +A 1 453 ALA 453 515 515 ALA ALA A . n +A 1 454 HIS 454 516 516 HIS HIS A . n +A 1 455 GLY 455 517 517 GLY GLY A . n +A 1 456 GLN 456 518 518 GLN GLN A . n +A 1 457 GLN 457 519 519 GLN GLN A . n +A 1 458 SER 458 520 520 SER SER A . n +A 1 459 VAL 459 521 521 VAL VAL A . n +A 1 460 ILE 460 522 522 ILE ILE A . n +A 1 461 VAL 461 523 523 VAL VAL A . n +A 1 462 ASP 462 524 524 ASP ASP A . n +A 1 463 GLY 463 525 525 GLY GLY A . n +A 1 464 PRO 464 526 526 PRO PRO A . n +A 1 465 VAL 465 527 ? ? ? A . n +A 1 466 GLU 466 528 ? ? ? A . n +A 1 467 GLN 467 529 ? ? ? A . n +B 2 1 MET 1 1 ? ? ? C . n +B 2 2 ILE 2 2 ? ? ? C . n +B 2 3 LEU 3 3 ? ? ? C . n +B 2 4 PHE 4 4 ? ? ? C . n +B 2 5 ARG 5 5 ? ? ? C . n +B 2 6 LYS 6 6 ? ? ? C . n +B 2 7 PHE 7 7 ? ? ? C . n +B 2 8 ARG 8 8 ? ? ? C . n +B 2 9 VAL 9 9 ? ? ? C . n +B 2 10 LEU 10 10 ? ? ? C . n +B 2 11 ILE 11 11 ? ? ? C . n +B 2 12 LEU 12 12 ? ? ? C . n +B 2 13 THR 13 13 ? ? ? C . n +B 2 14 VAL 14 14 ? ? ? C . n +B 2 15 PHE 15 15 ? ? ? C . n +B 2 16 LEU 16 16 ? ? ? C . n +B 2 17 ILE 17 17 ? ? ? C . n +B 2 18 ALA 18 18 ? ? ? C . n +B 2 19 CYS 19 19 ? ? ? C . n +B 2 20 THR 20 20 ? ? ? C . n +B 2 21 MET 21 21 ? ? ? C . n +B 2 22 HIS 22 22 ? ? ? C . n +B 2 23 ILE 23 23 ? ? ? C . n +B 2 24 MET 24 24 ? ? ? C . n +B 2 25 ILE 25 25 ? ? ? C . n +B 2 26 ASP 26 26 ? ? ? C . n +B 2 27 LEU 27 27 ? ? ? C . n +B 2 28 LEU 28 28 ? ? ? C . n +B 2 29 PRO 29 29 ? ? ? C . n +B 2 30 LYS 30 30 ? ? ? C . n +B 2 31 LEU 31 31 ? ? ? C . n +B 2 32 GLU 32 32 ? ? ? C . n +B 2 33 LYS 33 33 ? ? ? C . n +B 2 34 ARG 34 34 ? ? ? C . n +B 2 35 ALA 35 35 ? ? ? C . n +B 2 36 ALA 36 36 ? ? ? C . n +B 2 37 GLY 37 37 ? ? ? C . n +B 2 38 SER 38 38 ? ? ? C . n +B 2 39 SER 39 39 ? ? ? C . n +B 2 40 SER 40 40 ? ? ? C . n +B 2 41 SER 41 41 ? ? ? C . n +B 2 42 ALA 42 42 ? ? ? C . n +B 2 43 GLY 43 43 ? ? ? C . n +B 2 44 GLY 44 44 ? ? ? C . n +B 2 45 GLY 45 45 ? ? ? C . n +B 2 46 SER 46 46 ? ? ? C . n +B 2 47 GLY 47 47 ? ? ? C . n +B 2 48 CYS 48 48 ? ? ? C . n +B 2 49 SER 49 49 ? ? ? C . n +B 2 50 CYS 50 50 ? ? ? C . n +B 2 51 ALA 51 51 ? ? ? C . n +B 2 52 HIS 52 52 ? ? ? C . n +B 2 53 THR 53 53 ? ? ? C . n +B 2 54 PRO 54 54 ? ? ? C . n +B 2 55 GLY 55 55 ? ? ? C . n +B 2 56 GLU 56 56 ? ? ? C . n +B 2 57 GLU 57 57 ? ? ? C . n +B 2 58 PRO 58 58 ? ? ? C . n +B 2 59 ARG 59 59 ? ? ? C . n +B 2 60 SER 60 60 ? ? ? C . n +B 2 61 TRP 61 61 ? ? ? C . n +B 2 62 GLY 62 62 ? ? ? C . n +B 2 63 LYS 63 63 ? ? ? C . n +B 2 64 GLN 64 64 ? ? ? C . n +B 2 65 ARG 65 65 ? ? ? C . n +B 2 66 ALA 66 66 ? ? ? C . n +B 2 67 ARG 67 67 ? ? ? C . n +B 2 68 ALA 68 68 ? ? ? C . n +B 2 69 ALA 69 69 ? ? ? C . n +B 2 70 ASP 70 70 ? ? ? C . n +B 2 71 PRO 71 71 ? ? ? C . n +B 2 72 GLY 72 72 ? ? ? C . n +B 2 73 TRP 73 73 ? ? ? C . n +B 2 74 PRO 74 74 ? ? ? C . n +B 2 75 ASN 75 75 ? ? ? C . n +B 2 76 LYS 76 76 ? ? ? C . n +B 2 77 HIS 77 77 ? ? ? C . n +B 2 78 SER 78 78 ? ? ? C . n +B 2 79 LEU 79 79 ? ? ? C . n +B 2 80 ARG 80 80 ? ? ? C . n +B 2 81 LEU 81 81 ? ? ? C . n +B 2 82 LEU 82 82 ? ? ? C . n +B 2 83 GLN 83 83 ? ? ? C . n +B 2 84 ASP 84 84 ? ? ? C . n +B 2 85 PHE 85 85 ? ? ? C . n +B 2 86 SER 86 86 ? ? ? C . n +B 2 87 ASN 87 87 ? ? ? C . n +B 2 88 GLU 88 88 ? ? ? C . n +B 2 89 PRO 89 89 ? ? ? C . n +B 2 90 ASN 90 90 ? ? ? C . n +B 2 91 SER 91 91 ? ? ? C . n +B 2 92 ASN 92 92 ? ? ? C . n +B 2 93 LEU 93 93 ? ? ? C . n +B 2 94 THR 94 94 ? ? ? C . n +B 2 95 SER 95 95 ? ? ? C . n +B 2 96 GLN 96 96 ? ? ? C . n +B 2 97 SER 97 97 ? ? ? C . n +B 2 98 ARG 98 98 ? ? ? C . n +B 2 99 GLU 99 99 ? ? ? C . n +B 2 100 LYS 100 100 ? ? ? C . n +B 2 101 VAL 101 101 ? ? ? C . n +B 2 102 THR 102 102 ? ? ? C . n +B 2 103 GLU 103 103 ? ? ? C . n +B 2 104 ARG 104 104 ? ? ? C . n +B 2 105 ALA 105 105 ? ? ? C . n +B 2 106 GLY 106 106 ? ? ? C . n +B 2 107 SER 107 107 ? ? ? C . n +B 2 108 GLU 108 108 ? ? ? C . n +B 2 109 LYS 109 109 ? ? ? C . n +B 2 110 GLN 110 110 ? ? ? C . n +B 2 111 GLY 111 111 ? ? ? C . n +B 2 112 SER 112 112 ? ? ? C . n +B 2 113 GLY 113 113 ? ? ? C . n +B 2 114 LYS 114 114 ? ? ? C . n +B 2 115 ARG 115 115 ? ? ? C . n +B 2 116 GLY 116 116 ? ? ? C . n +B 2 117 LEU 117 117 ? ? ? C . n +B 2 118 MET 118 118 ? ? ? C . n +B 2 119 ARG 119 119 ? ? ? C . n +B 2 120 GLU 120 120 ? ? ? C . n +B 2 121 ALA 121 121 ? ? ? C . n +B 2 122 ASP 122 122 ? ? ? C . n +B 2 123 SER 123 123 ? ? ? C . n +B 2 124 ARG 124 124 ? ? ? C . n +B 2 125 GLN 125 125 ? ? ? C . n +B 2 126 ARG 126 126 ? ? ? C . n +B 2 127 ARG 127 127 ? ? ? C . n +B 2 128 THR 128 128 ? ? ? C . n +B 2 129 ASP 129 129 ? ? ? C . n +B 2 130 VAL 130 130 ? ? ? C . n +B 2 131 ARG 131 131 ? ? ? C . n +B 2 132 VAL 132 132 ? ? ? C . n +B 2 133 SER 133 133 ? ? ? C . n +B 2 134 SER 134 134 134 SER SER C . n +B 2 135 VAL 135 135 135 VAL VAL C . n +B 2 136 LEU 136 136 136 LEU LEU C . n +B 2 137 GLN 137 137 137 GLN GLN C . n +B 2 138 SER 138 138 138 SER SER C . n +B 2 139 LEU 139 139 139 LEU LEU C . n +B 2 140 PHE 140 140 140 PHE PHE C . n +B 2 141 GLU 141 141 141 GLU GLU C . n +B 2 142 HIS 142 142 142 HIS HIS C . n +B 2 143 PRO 143 143 143 PRO PRO C . n +B 2 144 LEU 144 144 144 LEU LEU C . n +B 2 145 TYR 145 145 145 TYR TYR C . n +B 2 146 ARG 146 146 146 ARG ARG C . n +B 2 147 THR 147 147 147 THR THR C . n +B 2 148 VAL 148 148 148 VAL VAL C . n +B 2 149 LEU 149 149 149 LEU LEU C . n +B 2 150 PRO 150 150 150 PRO PRO C . n +B 2 151 ASP 151 151 151 ASP ASP C . n +B 2 152 LEU 152 152 152 LEU LEU C . n +B 2 153 THR 153 153 153 THR THR C . n +B 2 154 GLU 154 154 154 GLU GLU C . n +B 2 155 GLU 155 155 155 GLU GLU C . n +B 2 156 ASP 156 156 156 ASP ASP C . n +B 2 157 THR 157 157 157 THR THR C . n +B 2 158 LEU 158 158 158 LEU LEU C . n +B 2 159 PHE 159 159 159 PHE PHE C . n +B 2 160 ASN 160 160 160 ASN ASN C . n +B 2 161 LEU 161 161 161 LEU LEU C . n +B 2 162 ASN 162 162 162 ASN ASN C . n +B 2 163 ALA 163 163 163 ALA ALA C . n +B 2 164 GLU 164 164 164 GLU GLU C . n +B 2 165 ILE 165 165 165 ILE ILE C . n +B 2 166 ARG 166 166 166 ARG ARG C . n +B 2 167 LEU 167 167 167 LEU LEU C . n +B 2 168 TYR 168 168 168 TYR TYR C . n +B 2 169 PRO 169 169 169 PRO PRO C . n +B 2 170 LYS 170 170 170 LYS LYS C . n +B 2 171 ALA 171 171 171 ALA ALA C . n +B 2 172 ALA 172 172 172 ALA ALA C . n +B 2 173 GLY 173 173 ? ? ? C . n +B 2 174 GLN 174 174 ? ? ? C . n +B 2 175 GLN 175 175 ? ? ? C . n +B 2 176 GLU 176 176 ? ? ? C . n +B 2 177 TRP 177 177 ? ? ? C . n +B 2 178 HIS 178 178 ? ? ? C . n +B 2 179 ASN 179 179 ? ? ? C . n +B 2 180 GLU 180 180 ? ? ? C . n +B 2 181 GLY 181 181 ? ? ? C . n +B 2 182 ASN 182 182 ? ? ? C . n +B 2 183 VAL 183 183 ? ? ? C . n +B 2 184 GLU 184 184 ? ? ? C . n +B 2 185 GLU 185 185 ? ? ? C . n +B 2 186 GLU 186 186 ? ? ? C . n +B 2 187 GLU 187 187 ? ? ? C . n +B 2 188 PHE 188 188 ? ? ? C . n +B 2 189 SER 189 189 ? ? ? C . n +B 2 190 PRO 190 190 ? ? ? C . n +B 2 191 PRO 191 191 ? ? ? C . n +B 2 192 GLY 192 192 ? ? ? C . n +B 2 193 GLU 193 193 ? ? ? C . n +B 2 194 ALA 194 194 ? ? ? C . n +B 2 195 ASN 195 195 ? ? ? C . n +B 2 196 SER 196 196 196 SER SER C . n +B 2 197 GLU 197 197 197 GLU GLU C . n +B 2 198 SER 198 198 198 SER SER C . n +B 2 199 TYR 199 199 199 TYR TYR C . n +B 2 200 PRO 200 200 200 PRO PRO C . n +B 2 201 ASN 201 201 201 ASN ASN C . n +B 2 202 TRP 202 202 202 TRP TRP C . n +B 2 203 LEU 203 203 203 LEU LEU C . n +B 2 204 ARG 204 204 204 ARG ARG C . n +B 2 205 PHE 205 205 205 PHE PHE C . n +B 2 206 HIS 206 206 206 HIS HIS C . n +B 2 207 ILE 207 207 207 ILE ILE C . n +B 2 208 GLY 208 208 208 GLY GLY C . n +B 2 209 ILE 209 209 209 ILE ILE C . n +B 2 210 ASN 210 210 210 ASN ASN C . n +B 2 211 ARG 211 211 211 ARG ARG C . n +B 2 212 TYR 212 212 212 TYR TYR C . n +B 2 213 GLU 213 213 213 GLU GLU C . n +B 2 214 LEU 214 214 214 LEU LEU C . n +B 2 215 TYR 215 215 215 TYR TYR C . n +B 2 216 SER 216 216 216 SER SER C . n +B 2 217 ARG 217 217 217 ARG ARG C . n +B 2 218 HIS 218 218 218 HIS HIS C . n +B 2 219 ASN 219 219 219 ASN ASN C . n +B 2 220 PRO 220 220 220 PRO PRO C . n +B 2 221 VAL 221 221 221 VAL VAL C . n +B 2 222 ILE 222 222 222 ILE ILE C . n +B 2 223 ALA 223 223 223 ALA ALA C . n +B 2 224 ALA 224 224 224 ALA ALA C . n +B 2 225 LEU 225 225 225 LEU LEU C . n +B 2 226 LEU 226 226 226 LEU LEU C . n +B 2 227 ARG 227 227 227 ARG ARG C . n +B 2 228 ASP 228 228 228 ASP ASP C . n +B 2 229 LEU 229 229 229 LEU LEU C . n +B 2 230 LEU 230 230 230 LEU LEU C . n +B 2 231 SER 231 231 231 SER SER C . n +B 2 232 GLN 232 232 232 GLN GLN C . n +B 2 233 LYS 233 233 233 LYS LYS C . n +B 2 234 ILE 234 234 234 ILE ILE C . n +B 2 235 SER 235 235 235 SER SER C . n +B 2 236 SER 236 236 236 SER SER C . n +B 2 237 VAL 237 237 237 VAL VAL C . n +B 2 238 GLY 238 238 238 GLY GLY C . n +B 2 239 MET 239 239 239 MET MET C . n +B 2 240 LYS 240 240 240 LYS LYS C . n +B 2 241 SER 241 241 241 SER SER C . n +B 2 242 GLY 242 242 242 GLY GLY C . n +B 2 243 GLY 243 243 243 GLY GLY C . n +B 2 244 THR 244 244 244 THR THR C . n +B 2 245 GLN 245 245 245 GLN GLN C . n +B 2 246 LEU 246 246 246 LEU LEU C . n +B 2 247 LYS 247 247 247 LYS LYS C . n +B 2 248 LEU 248 248 248 LEU LEU C . n +B 2 249 ILE 249 249 249 ILE ILE C . n +B 2 250 MET 250 250 250 MET MET C . n +B 2 251 SER 251 251 251 SER SER C . n +B 2 252 PHE 252 252 252 PHE PHE C . n +B 2 253 GLN 253 253 253 GLN GLN C . n +B 2 254 ASN 254 254 254 ASN ASN C . n +B 2 255 TYR 255 255 255 TYR TYR C . n +B 2 256 GLY 256 256 256 GLY GLY C . n +B 2 257 GLN 257 257 257 GLN GLN C . n +B 2 258 ALA 258 258 258 ALA ALA C . n +B 2 259 LEU 259 259 259 LEU LEU C . n +B 2 260 PHE 260 260 260 PHE PHE C . n +B 2 261 LYS 261 261 261 LYS LYS C . n +B 2 262 PRO 262 262 262 PRO PRO C . n +B 2 263 MET 263 263 263 MET MET C . n +B 2 264 LYS 264 264 264 LYS LYS C . n +B 2 265 GLN 265 265 265 GLN GLN C . n +B 2 266 THR 266 266 266 THR THR C . n +B 2 267 ARG 267 267 267 ARG ARG C . n +B 2 268 GLU 268 268 268 GLU GLU C . n +B 2 269 GLN 269 269 269 GLN GLN C . n +B 2 270 GLU 270 270 270 GLU GLU C . n +B 2 271 THR 271 271 271 THR THR C . n +B 2 272 PRO 272 272 272 PRO PRO C . n +B 2 273 PRO 273 273 273 PRO PRO C . n +B 2 274 ASP 274 274 274 ASP ASP C . n +B 2 275 PHE 275 275 275 PHE PHE C . n +B 2 276 PHE 276 276 276 PHE PHE C . n +B 2 277 TYR 277 277 277 TYR TYR C . n +B 2 278 PHE 278 278 278 PHE PHE C . n +B 2 279 SER 279 279 279 SER SER C . n +B 2 280 ASP 280 280 280 ASP ASP C . n +B 2 281 PHE 281 281 281 PHE PHE C . n +B 2 282 GLU 282 282 282 GLU GLU C . n +B 2 283 ARG 283 283 283 ARG ARG C . n +B 2 284 HIS 284 284 284 HIS HIS C . n +B 2 285 ASN 285 285 285 ASN ASN C . n +B 2 286 ALA 286 286 286 ALA ALA C . n +B 2 287 GLU 287 287 287 GLU GLU C . n +B 2 288 ILE 288 288 288 ILE ILE C . n +B 2 289 ALA 289 289 289 ALA ALA C . n +B 2 290 ALA 290 290 290 ALA ALA C . n +B 2 291 PHE 291 291 291 PHE PHE C . n +B 2 292 HIS 292 292 292 HIS HIS C . n +B 2 293 LEU 293 293 293 LEU LEU C . n +B 2 294 ASP 294 294 294 ASP ASP C . n +B 2 295 ARG 295 295 295 ARG ARG C . n +B 2 296 ILE 296 296 296 ILE ILE C . n +B 2 297 LEU 297 297 297 LEU LEU C . n +B 2 298 ASP 298 298 298 ASP ASP C . n +B 2 299 PHE 299 299 299 PHE PHE C . n +B 2 300 ARG 300 300 300 ARG ARG C . n +B 2 301 ARG 301 301 301 ARG ARG C . n +B 2 302 VAL 302 302 302 VAL VAL C . n +B 2 303 PRO 303 303 303 PRO PRO C . n +B 2 304 PRO 304 304 304 PRO PRO C . n +B 2 305 VAL 305 305 305 VAL VAL C . n +B 2 306 ALA 306 306 306 ALA ALA C . n +B 2 307 GLY 307 307 307 GLY GLY C . n +B 2 308 ARG 308 308 308 ARG ARG C . n +B 2 309 LEU 309 309 309 LEU LEU C . n +B 2 310 VAL 310 310 310 VAL VAL C . n +B 2 311 ASN 311 311 311 ASN ASN C . n +B 2 312 MET 312 312 312 MET MET C . n +B 2 313 THR 313 313 313 THR THR C . n +B 2 314 ARG 314 314 314 ARG ARG C . n +B 2 315 GLU 315 315 315 GLU GLU C . n +B 2 316 ILE 316 316 316 ILE ILE C . n +B 2 317 ARG 317 317 317 ARG ARG C . n +B 2 318 ASP 318 318 318 ASP ASP C . n +B 2 319 VAL 319 319 319 VAL VAL C . n +B 2 320 THR 320 320 320 THR THR C . n +B 2 321 ARG 321 321 321 ARG ARG C . n +B 2 322 ASP 322 322 322 ASP ASP C . n +B 2 323 LYS 323 323 323 LYS LYS C . n +B 2 324 LYS 324 324 324 LYS LYS C . n +B 2 325 LEU 325 325 325 LEU LEU C . n +B 2 326 TRP 326 326 326 TRP TRP C . n +B 2 327 ARG 327 327 327 ARG ARG C . n +B 2 328 THR 328 328 328 THR THR C . n +B 2 329 PHE 329 329 329 PHE PHE C . n +B 2 330 PHE 330 330 330 PHE PHE C . n +B 2 331 VAL 331 331 331 VAL VAL C . n +B 2 332 SER 332 332 332 SER SER C . n +B 2 333 PRO 333 333 333 PRO PRO C . n +B 2 334 ALA 334 334 334 ALA ALA C . n +B 2 335 ASN 335 335 335 ASN ASN C . n +B 2 336 ASN 336 336 336 ASN ASN C . n +B 2 337 ILE 337 337 337 ILE ILE C . n +B 2 338 CYS 338 338 338 CYS CYS C . n +B 2 339 PHE 339 339 339 PHE PHE C . n +B 2 340 TYR 340 340 340 TYR TYR C . n +B 2 341 GLY 341 341 341 GLY GLY C . n +B 2 342 GLU 342 342 342 GLU GLU C . n +B 2 343 CYS 343 343 343 CYS CYS C . n +B 2 344 SER 344 344 344 SER SER C . n +B 2 345 TYR 345 345 345 TYR TYR C . n +B 2 346 TYR 346 346 346 TYR TYR C . n +B 2 347 CYS 347 347 347 CYS CYS C . n +B 2 348 SER 348 348 348 SER SER C . n +B 2 349 THR 349 349 349 THR THR C . n +B 2 350 GLU 350 350 350 GLU GLU C . n +B 2 351 HIS 351 351 351 HIS HIS C . n +B 2 352 ALA 352 352 352 ALA ALA C . n +B 2 353 LEU 353 353 353 LEU LEU C . n +B 2 354 CYS 354 354 354 CYS CYS C . n +B 2 355 GLY 355 355 355 GLY GLY C . n +B 2 356 LYS 356 356 356 LYS LYS C . n +B 2 357 PRO 357 357 357 PRO PRO C . n +B 2 358 ASP 358 358 358 ASP ASP C . n +B 2 359 GLN 359 359 359 GLN GLN C . n +B 2 360 ILE 360 360 360 ILE ILE C . n +B 2 361 GLU 361 361 361 GLU GLU C . n +B 2 362 GLY 362 362 362 GLY GLY C . n +B 2 363 SER 363 363 363 SER SER C . n +B 2 364 LEU 364 364 364 LEU LEU C . n +B 2 365 ALA 365 365 365 ALA ALA C . n +B 2 366 ALA 366 366 366 ALA ALA C . n +B 2 367 PHE 367 367 367 PHE PHE C . n +B 2 368 LEU 368 368 368 LEU LEU C . n +B 2 369 PRO 369 369 369 PRO PRO C . n +B 2 370 ASP 370 370 370 ASP ASP C . n +B 2 371 LEU 371 371 371 LEU LEU C . n +B 2 372 ALA 372 372 372 ALA ALA C . n +B 2 373 LEU 373 373 373 LEU LEU C . n +B 2 374 ALA 374 374 374 ALA ALA C . n +B 2 375 LYS 375 375 375 LYS LYS C . n +B 2 376 ARG 376 376 376 ARG ARG C . n +B 2 377 LYS 377 377 377 LYS LYS C . n +B 2 378 THR 378 378 378 THR THR C . n +B 2 379 TRP 379 379 379 TRP TRP C . n +B 2 380 ARG 380 380 380 ARG ARG C . n +B 2 381 ASN 381 381 381 ASN ASN C . n +B 2 382 PRO 382 382 382 PRO PRO C . n +B 2 383 TRP 383 383 383 TRP TRP C . n +B 2 384 ARG 384 384 384 ARG ARG C . n +B 2 385 ARG 385 385 385 ARG ARG C . n +B 2 386 SER 386 386 386 SER SER C . n +B 2 387 TYR 387 387 387 TYR TYR C . n +B 2 388 HIS 388 388 388 HIS HIS C . n +B 2 389 LYS 389 389 389 LYS LYS C . n +B 2 390 ARG 390 390 390 ARG ARG C . n +B 2 391 LYS 391 391 391 LYS LYS C . n +B 2 392 LYS 392 392 392 LYS LYS C . n +B 2 393 ALA 393 393 393 ALA ALA C . n +B 2 394 GLU 394 394 394 GLU GLU C . n +B 2 395 TRP 395 395 395 TRP TRP C . n +B 2 396 GLU 396 396 396 GLU GLU C . n +B 2 397 VAL 397 397 397 VAL VAL C . n +B 2 398 ASP 398 398 398 ASP ASP C . n +B 2 399 PRO 399 399 399 PRO PRO C . n +B 2 400 ASP 400 400 400 ASP ASP C . n +B 2 401 TYR 401 401 401 TYR TYR C . n +B 2 402 CYS 402 402 402 CYS CYS C . n +B 2 403 ASP 403 403 403 ASP ASP C . n +B 2 404 GLU 404 404 404 GLU GLU C . n +B 2 405 VAL 405 405 405 VAL VAL C . n +B 2 406 LYS 406 406 406 LYS LYS C . n +B 2 407 GLN 407 407 407 GLN GLN C . n +B 2 408 THR 408 408 408 THR THR C . n +B 2 409 PRO 409 409 409 PRO PRO C . n +B 2 410 PRO 410 410 410 PRO PRO C . n +B 2 411 TYR 411 411 411 TYR TYR C . n +B 2 412 ASP 412 412 412 ASP ASP C . n +B 2 413 ARG 413 413 413 ARG ARG C . n +B 2 414 GLY 414 414 414 GLY GLY C . n +B 2 415 THR 415 415 415 THR THR C . n +B 2 416 ARG 416 416 416 ARG ARG C . n +B 2 417 LEU 417 417 417 LEU LEU C . n +B 2 418 LEU 418 418 418 LEU LEU C . n +B 2 419 ASP 419 419 419 ASP ASP C . n +B 2 420 ILE 420 420 420 ILE ILE C . n +B 2 421 MET 421 421 421 MET MET C . n +B 2 422 ASP 422 422 422 ASP ASP C . n +B 2 423 MET 423 423 423 MET MET C . n +B 2 424 THR 424 424 424 THR THR C . n +B 2 425 ILE 425 425 425 ILE ILE C . n +B 2 426 PHE 426 426 426 PHE PHE C . n +B 2 427 ASP 427 427 427 ASP ASP C . n +B 2 428 PHE 428 428 428 PHE PHE C . n +B 2 429 LEU 429 429 429 LEU LEU C . n +B 2 430 MET 430 430 430 MET MET C . n +B 2 431 GLY 431 431 431 GLY GLY C . n +B 2 432 ASN 432 432 432 ASN ASN C . n +B 2 433 MET 433 433 433 MET MET C . n +B 2 434 ASP 434 434 434 ASP ASP C . n +B 2 435 ARG 435 435 435 ARG ARG C . n +B 2 436 HIS 436 436 436 HIS HIS C . n +B 2 437 HIS 437 437 437 HIS HIS C . n +B 2 438 TYR 438 438 438 TYR TYR C . n +B 2 439 GLU 439 439 439 GLU GLU C . n +B 2 440 THR 440 440 440 THR THR C . n +B 2 441 PHE 441 441 441 PHE PHE C . n +B 2 442 GLU 442 442 442 GLU GLU C . n +B 2 443 LYS 443 443 443 LYS LYS C . n +B 2 444 PHE 444 444 444 PHE PHE C . n +B 2 445 GLY 445 445 445 GLY GLY C . n +B 2 446 ASN 446 446 446 ASN ASN C . n +B 2 447 ASP 447 447 447 ASP ASP C . n +B 2 448 THR 448 448 448 THR THR C . n +B 2 449 PHE 449 449 449 PHE PHE C . n +B 2 450 ILE 450 450 450 ILE ILE C . n +B 2 451 ILE 451 451 451 ILE ILE C . n +B 2 452 HIS 452 452 452 HIS HIS C . n +B 2 453 LEU 453 453 453 LEU LEU C . n +B 2 454 ASP 454 454 454 ASP ASP C . n +B 2 455 ASN 455 455 455 ASN ASN C . n +B 2 456 GLY 456 456 456 GLY GLY C . n +B 2 457 ARG 457 457 457 ARG ARG C . n +B 2 458 GLY 458 458 458 GLY GLY C . n +B 2 459 PHE 459 459 459 PHE PHE C . n +B 2 460 GLY 460 460 460 GLY GLY C . n +B 2 461 LYS 461 461 461 LYS LYS C . n +B 2 462 HIS 462 462 462 HIS HIS C . n +B 2 463 SER 463 463 463 SER SER C . n +B 2 464 HIS 464 464 464 HIS HIS C . n +B 2 465 ASP 465 465 465 ASP ASP C . n +B 2 466 GLU 466 466 466 GLU GLU C . n +B 2 467 MET 467 467 467 MET MET C . n +B 2 468 SER 468 468 468 SER SER C . n +B 2 469 ILE 469 469 469 ILE ILE C . n +B 2 470 LEU 470 470 470 LEU LEU C . n +B 2 471 VAL 471 471 471 VAL VAL C . n +B 2 472 PRO 472 472 472 PRO PRO C . n +B 2 473 LEU 473 473 473 LEU LEU C . n +B 2 474 THR 474 474 474 THR THR C . n +B 2 475 GLN 475 475 475 GLN GLN C . n +B 2 476 CYS 476 476 476 CYS CYS C . n +B 2 477 CYS 477 477 477 CYS CYS C . n +B 2 478 ARG 478 478 478 ARG ARG C . n +B 2 479 VAL 479 479 479 VAL VAL C . n +B 2 480 LYS 480 480 480 LYS LYS C . n +B 2 481 ARG 481 481 481 ARG ARG C . n +B 2 482 SER 482 482 482 SER SER C . n +B 2 483 THR 483 483 483 THR THR C . n +B 2 484 TYR 484 484 484 TYR TYR C . n +B 2 485 LEU 485 485 485 LEU LEU C . n +B 2 486 ARG 486 486 486 ARG ARG C . n +B 2 487 LEU 487 487 487 LEU LEU C . n +B 2 488 GLN 488 488 488 GLN GLN C . n +B 2 489 LEU 489 489 489 LEU LEU C . n +B 2 490 LEU 490 490 490 LEU LEU C . n +B 2 491 ALA 491 491 491 ALA ALA C . n +B 2 492 LYS 492 492 492 LYS LYS C . n +B 2 493 GLU 493 493 493 GLU GLU C . n +B 2 494 GLU 494 494 494 GLU GLU C . n +B 2 495 TYR 495 495 495 TYR TYR C . n +B 2 496 LYS 496 496 496 LYS LYS C . n +B 2 497 LEU 497 497 497 LEU LEU C . n +B 2 498 SER 498 498 498 SER SER C . n +B 2 499 SER 499 499 499 SER SER C . n +B 2 500 LEU 500 500 500 LEU LEU C . n +B 2 501 MET 501 501 501 MET MET C . n +B 2 502 GLU 502 502 502 GLU GLU C . n +B 2 503 GLU 503 503 503 GLU GLU C . n +B 2 504 SER 504 504 504 SER SER C . n +B 2 505 LEU 505 505 505 LEU LEU C . n +B 2 506 LEU 506 506 506 LEU LEU C . n +B 2 507 GLN 507 507 507 GLN GLN C . n +B 2 508 ASP 508 508 508 ASP ASP C . n +B 2 509 ARG 509 509 509 ARG ARG C . n +B 2 510 LEU 510 510 510 LEU LEU C . n +B 2 511 VAL 511 511 511 VAL VAL C . n +B 2 512 PRO 512 512 512 PRO PRO C . n +B 2 513 VAL 513 513 513 VAL VAL C . n +B 2 514 LEU 514 514 514 LEU LEU C . n +B 2 515 ILE 515 515 515 ILE ILE C . n +B 2 516 LYS 516 516 516 LYS LYS C . n +B 2 517 PRO 517 517 517 PRO PRO C . n +B 2 518 HIS 518 518 518 HIS HIS C . n +B 2 519 LEU 519 519 519 LEU LEU C . n +B 2 520 GLU 520 520 520 GLU GLU C . n +B 2 521 ALA 521 521 521 ALA ALA C . n +B 2 522 LEU 522 522 522 LEU LEU C . n +B 2 523 ASP 523 523 523 ASP ASP C . n +B 2 524 ARG 524 524 524 ARG ARG C . n +B 2 525 ARG 525 525 525 ARG ARG C . n +B 2 526 LEU 526 526 526 LEU LEU C . n +B 2 527 ARG 527 527 527 ARG ARG C . n +B 2 528 LEU 528 528 528 LEU LEU C . n +B 2 529 VAL 529 529 529 VAL VAL C . n +B 2 530 LEU 530 530 530 LEU LEU C . n +B 2 531 LYS 531 531 531 LYS LYS C . n +B 2 532 VAL 532 532 532 VAL VAL C . n +B 2 533 LEU 533 533 533 LEU LEU C . n +B 2 534 SER 534 534 534 SER SER C . n +B 2 535 ASP 535 535 535 ASP ASP C . n +B 2 536 CYS 536 536 536 CYS CYS C . n +B 2 537 VAL 537 537 537 VAL VAL C . n +B 2 538 GLU 538 538 538 GLU GLU C . n +B 2 539 LYS 539 539 539 LYS LYS C . n +B 2 540 ASP 540 540 540 ASP ASP C . n +B 2 541 GLY 541 541 541 GLY GLY C . n +B 2 542 PHE 542 542 542 PHE PHE C . n +B 2 543 SER 543 543 543 SER SER C . n +B 2 544 ALA 544 544 544 ALA ALA C . n +B 2 545 VAL 545 545 545 VAL VAL C . n +B 2 546 VAL 546 546 546 VAL VAL C . n +B 2 547 GLU 547 547 547 GLU GLU C . n +B 2 548 ASN 548 548 548 ASN ASN C . n +B 2 549 ASP 549 549 549 ASP ASP C . n +B 2 550 LEU 550 550 550 LEU LEU C . n +B 2 551 ASP 551 551 551 ASP ASP C . n +B 2 552 GLY 552 552 ? ? ? C . n +B 2 553 GLN 553 553 ? ? ? C . n +B 2 554 PRO 554 554 ? ? ? C . n +B 2 555 SER 555 555 ? ? ? C . n +B 2 556 VAL 556 556 ? ? ? C . n +B 2 557 HIS 557 557 ? ? ? C . n +B 2 558 GLY 558 558 ? ? ? C . n +B 2 559 GLY 559 559 ? ? ? C . n +B 2 560 ARG 560 560 ? ? ? C . n +C 1 1 ASP 1 63 ? ? ? B . n +C 1 2 PRO 2 64 ? ? ? B . n +C 1 3 GLY 3 65 ? ? ? B . n +C 1 4 THR 4 66 ? ? ? B . n +C 1 5 ILE 5 67 ? ? ? B . n +C 1 6 VAL 6 68 ? ? ? B . n +C 1 7 HIS 7 69 ? ? ? B . n +C 1 8 ASN 8 70 ? ? ? B . n +C 1 9 PHE 9 71 ? ? ? B . n +C 1 10 SER 10 72 ? ? ? B . n +C 1 11 ARG 11 73 ? ? ? B . n +C 1 12 THR 12 74 ? ? ? B . n +C 1 13 GLU 13 75 ? ? ? B . n +C 1 14 PRO 14 76 ? ? ? B . n +C 1 15 ARG 15 77 ? ? ? B . n +C 1 16 THR 16 78 ? ? ? B . n +C 1 17 GLU 17 79 ? ? ? B . n +C 1 18 PRO 18 80 ? ? ? B . n +C 1 19 ALA 19 81 ? ? ? B . n +C 1 20 GLY 20 82 ? ? ? B . n +C 1 21 GLY 21 83 ? ? ? B . n +C 1 22 SER 22 84 ? ? ? B . n +C 1 23 HIS 23 85 ? ? ? B . n +C 1 24 SER 24 86 ? ? ? B . n +C 1 25 GLY 25 87 ? ? ? B . n +C 1 26 SER 26 88 ? ? ? B . n +C 1 27 SER 27 89 89 SER SER B . n +C 1 28 SER 28 90 90 SER SER B . n +C 1 29 LYS 29 91 91 LYS LYS B . n +C 1 30 LEU 30 92 92 LEU LEU B . n +C 1 31 GLN 31 93 93 GLN GLN B . n +C 1 32 ALA 32 94 94 ALA ALA B . n +C 1 33 LEU 33 95 95 LEU LEU B . n +C 1 34 PHE 34 96 96 PHE PHE B . n +C 1 35 ALA 35 97 97 ALA ALA B . n +C 1 36 HIS 36 98 98 HIS HIS B . n +C 1 37 PRO 37 99 99 PRO PRO B . n +C 1 38 LEU 38 100 100 LEU LEU B . n +C 1 39 TYR 39 101 101 TYR TYR B . n +C 1 40 ASN 40 102 102 ASN ASN B . n +C 1 41 VAL 41 103 103 VAL VAL B . n +C 1 42 PRO 42 104 104 PRO PRO B . n +C 1 43 GLU 43 105 105 GLU GLU B . n +C 1 44 GLU 44 106 106 GLU GLU B . n +C 1 45 PRO 45 107 107 PRO PRO B . n +C 1 46 PRO 46 108 108 PRO PRO B . n +C 1 47 LEU 47 109 109 LEU LEU B . n +C 1 48 LEU 48 110 110 LEU LEU B . n +C 1 49 GLY 49 111 111 GLY GLY B . n +C 1 50 ALA 50 112 112 ALA ALA B . n +C 1 51 GLU 51 113 113 GLU GLU B . n +C 1 52 ASP 52 114 114 ASP ASP B . n +C 1 53 SER 53 115 115 SER SER B . n +C 1 54 LEU 54 116 116 LEU LEU B . n +C 1 55 LEU 55 117 117 LEU LEU B . n +C 1 56 ALA 56 118 118 ALA ALA B . n +C 1 57 SER 57 119 119 SER SER B . n +C 1 58 GLN 58 120 120 GLN GLN B . n +C 1 59 GLU 59 121 121 GLU GLU B . n +C 1 60 ALA 60 122 122 ALA ALA B . n +C 1 61 LEU 61 123 123 LEU LEU B . n +C 1 62 ARG 62 124 124 ARG ARG B . n +C 1 63 TYR 63 125 125 TYR TYR B . n +C 1 64 TYR 64 126 126 TYR TYR B . n +C 1 65 ARG 65 127 127 ARG ARG B . n +C 1 66 ARG 66 128 128 ARG ARG B . n +C 1 67 LYS 67 129 129 LYS LYS B . n +C 1 68 VAL 68 130 130 VAL VAL B . n +C 1 69 ALA 69 131 131 ALA ALA B . n +C 1 70 ARG 70 132 132 ARG ARG B . n +C 1 71 TRP 71 133 133 TRP TRP B . n +C 1 72 ASN 72 134 134 ASN ASN B . n +C 1 73 ARG 73 135 135 ARG ARG B . n +C 1 74 ARG 74 136 136 ARG ARG B . n +C 1 75 HIS 75 137 137 HIS HIS B . n +C 1 76 LYS 76 138 138 LYS LYS B . n +C 1 77 MET 77 139 139 MET MET B . n +C 1 78 TYR 78 140 140 TYR TYR B . n +C 1 79 ARG 79 141 ? ? ? B . n +C 1 80 GLU 80 142 ? ? ? B . n +C 1 81 GLN 81 143 ? ? ? B . n +C 1 82 MET 82 144 ? ? ? B . n +C 1 83 ASN 83 145 ? ? ? B . n +C 1 84 LEU 84 146 ? ? ? B . n +C 1 85 THR 85 147 ? ? ? B . n +C 1 86 SER 86 148 ? ? ? B . n +C 1 87 LEU 87 149 ? ? ? B . n +C 1 88 ASP 88 150 ? ? ? B . n +C 1 89 PRO 89 151 151 PRO PRO B . n +C 1 90 PRO 90 152 152 PRO PRO B . n +C 1 91 LEU 91 153 153 LEU LEU B . n +C 1 92 GLN 92 154 154 GLN GLN B . n +C 1 93 LEU 93 155 155 LEU LEU B . n +C 1 94 ARG 94 156 156 ARG ARG B . n +C 1 95 LEU 95 157 157 LEU LEU B . n +C 1 96 GLU 96 158 158 GLU GLU B . n +C 1 97 ALA 97 159 159 ALA ALA B . n +C 1 98 SER 98 160 160 SER SER B . n +C 1 99 TRP 99 161 161 TRP TRP B . n +C 1 100 VAL 100 162 162 VAL VAL B . n +C 1 101 GLN 101 163 163 GLN GLN B . n +C 1 102 PHE 102 164 164 PHE PHE B . n +C 1 103 HIS 103 165 165 HIS HIS B . n +C 1 104 LEU 104 166 166 LEU LEU B . n +C 1 105 GLY 105 167 167 GLY GLY B . n +C 1 106 ILE 106 168 168 ILE ILE B . n +C 1 107 ASN 107 169 169 ASN ASN B . n +C 1 108 ARG 108 170 170 ARG ARG B . n +C 1 109 HIS 109 171 171 HIS HIS B . n +C 1 110 GLY 110 172 172 GLY GLY B . n +C 1 111 LEU 111 173 173 LEU LEU B . n +C 1 112 TYR 112 174 174 TYR TYR B . n +C 1 113 SER 113 175 175 SER SER B . n +C 1 114 ARG 114 176 176 ARG ARG B . n +C 1 115 SER 115 177 177 SER SER B . n +C 1 116 SER 116 178 178 SER SER B . n +C 1 117 PRO 117 179 179 PRO PRO B . n +C 1 118 VAL 118 180 180 VAL VAL B . n +C 1 119 VAL 119 181 181 VAL VAL B . n +C 1 120 SER 120 182 182 SER SER B . n +C 1 121 LYS 121 183 183 LYS LYS B . n +C 1 122 LEU 122 184 184 LEU LEU B . n +C 1 123 LEU 123 185 185 LEU LEU B . n +C 1 124 GLN 124 186 186 GLN GLN B . n +C 1 125 ASP 125 187 187 ASP ASP B . n +C 1 126 MET 126 188 188 MET MET B . n +C 1 127 ARG 127 189 189 ARG ARG B . n +C 1 128 HIS 128 190 190 HIS HIS B . n +C 1 129 PHE 129 191 191 PHE PHE B . n +C 1 130 PRO 130 192 192 PRO PRO B . n +C 1 131 THR 131 193 193 THR THR B . n +C 1 132 ILE 132 194 194 ILE ILE B . n +C 1 133 SER 133 195 195 SER SER B . n +C 1 134 ALA 134 196 196 ALA ALA B . n +C 1 135 ASP 135 197 197 ASP ASP B . n +C 1 136 TYR 136 198 198 TYR TYR B . n +C 1 137 SER 137 199 199 SER SER B . n +C 1 138 GLN 138 200 200 GLN GLN B . n +C 1 139 ASP 139 201 201 ASP ASP B . n +C 1 140 GLU 140 202 202 GLU GLU B . n +C 1 141 LYS 141 203 203 LYS LYS B . n +C 1 142 ALA 142 204 204 ALA ALA B . n +C 1 143 LEU 143 205 205 LEU LEU B . n +C 1 144 LEU 144 206 206 LEU LEU B . n +C 1 145 GLY 145 207 207 GLY GLY B . n +C 1 146 ALA 146 208 208 ALA ALA B . n +C 1 147 CYS 147 209 209 CYS CYS B . n +C 1 148 ASP 148 210 210 ASP ASP B . n +C 1 149 CYS 149 211 211 CYS CYS B . n +C 1 150 THR 150 212 212 THR THR B . n +C 1 151 GLN 151 213 213 GLN GLN B . n +C 1 152 ILE 152 214 214 ILE ILE B . n +C 1 153 VAL 153 215 215 VAL VAL B . n +C 1 154 LYS 154 216 216 LYS LYS B . n +C 1 155 PRO 155 217 217 PRO PRO B . n +C 1 156 SER 156 218 218 SER SER B . n +C 1 157 GLY 157 219 219 GLY GLY B . n +C 1 158 VAL 158 220 220 VAL VAL B . n +C 1 159 HIS 159 221 221 HIS HIS B . n +C 1 160 LEU 160 222 222 LEU LEU B . n +C 1 161 LYS 161 223 223 LYS LYS B . n +C 1 162 LEU 162 224 224 LEU LEU B . n +C 1 163 VAL 163 225 225 VAL VAL B . n +C 1 164 LEU 164 226 226 LEU LEU B . n +C 1 165 ARG 165 227 227 ARG ARG B . n +C 1 166 PHE 166 228 228 PHE PHE B . n +C 1 167 SER 167 229 229 SER SER B . n +C 1 168 ASP 168 230 230 ASP ASP B . n +C 1 169 PHE 169 231 231 PHE PHE B . n +C 1 170 GLY 170 232 232 GLY GLY B . n +C 1 171 LYS 171 233 233 LYS LYS B . n +C 1 172 ALA 172 234 234 ALA ALA B . n +C 1 173 MET 173 235 235 MET MET B . n +C 1 174 PHE 174 236 236 PHE PHE B . n +C 1 175 LYS 175 237 237 LYS LYS B . n +C 1 176 PRO 176 238 238 PRO PRO B . n +C 1 177 MET 177 239 239 MET MET B . n +C 1 178 ARG 178 240 240 ARG ARG B . n +C 1 179 GLN 179 241 241 GLN GLN B . n +C 1 180 GLN 180 242 242 GLN GLN B . n +C 1 181 ARG 181 243 243 ARG ARG B . n +C 1 182 ASP 182 244 244 ASP ASP B . n +C 1 183 GLU 183 245 245 GLU GLU B . n +C 1 184 GLU 184 246 246 GLU GLU B . n +C 1 185 THR 185 247 247 THR THR B . n +C 1 186 PRO 186 248 248 PRO PRO B . n +C 1 187 VAL 187 249 249 VAL VAL B . n +C 1 188 ASP 188 250 250 ASP ASP B . n +C 1 189 PHE 189 251 251 PHE PHE B . n +C 1 190 PHE 190 252 252 PHE PHE B . n +C 1 191 TYR 191 253 253 TYR TYR B . n +C 1 192 PHE 192 254 254 PHE PHE B . n +C 1 193 ILE 193 255 255 ILE ILE B . n +C 1 194 ASP 194 256 256 ASP ASP B . n +C 1 195 PHE 195 257 257 PHE PHE B . n +C 1 196 GLN 196 258 258 GLN GLN B . n +C 1 197 ARG 197 259 259 ARG ARG B . n +C 1 198 HIS 198 260 260 HIS HIS B . n +C 1 199 ASN 199 261 261 ASN ASN B . n +C 1 200 ALA 200 262 262 ALA ALA B . n +C 1 201 GLU 201 263 263 GLU GLU B . n +C 1 202 ILE 202 264 264 ILE ILE B . n +C 1 203 ALA 203 265 265 ALA ALA B . n +C 1 204 ALA 204 266 266 ALA ALA B . n +C 1 205 PHE 205 267 267 PHE PHE B . n +C 1 206 HIS 206 268 268 HIS HIS B . n +C 1 207 LEU 207 269 269 LEU LEU B . n +C 1 208 ASP 208 270 270 ASP ASP B . n +C 1 209 ARG 209 271 271 ARG ARG B . n +C 1 210 ILE 210 272 272 ILE ILE B . n +C 1 211 LEU 211 273 273 LEU LEU B . n +C 1 212 ASP 212 274 274 ASP ASP B . n +C 1 213 PHE 213 275 275 PHE PHE B . n +C 1 214 ARG 214 276 276 ARG ARG B . n +C 1 215 ARG 215 277 277 ARG ARG B . n +C 1 216 VAL 216 278 278 VAL VAL B . n +C 1 217 PRO 217 279 279 PRO PRO B . n +C 1 218 PRO 218 280 280 PRO PRO B . n +C 1 219 THR 219 281 281 THR THR B . n +C 1 220 VAL 220 282 282 VAL VAL B . n +C 1 221 GLY 221 283 283 GLY GLY B . n +C 1 222 ARG 222 284 284 ARG ARG B . n +C 1 223 ILE 223 285 285 ILE ILE B . n +C 1 224 VAL 224 286 286 VAL VAL B . n +C 1 225 ASN 225 287 287 ASN ASN B . n +C 1 226 VAL 226 288 288 VAL VAL B . n +C 1 227 THR 227 289 289 THR THR B . n +C 1 228 LYS 228 290 290 LYS LYS B . n +C 1 229 GLU 229 291 291 GLU GLU B . n +C 1 230 ILE 230 292 292 ILE ILE B . n +C 1 231 LEU 231 293 293 LEU LEU B . n +C 1 232 GLU 232 294 294 GLU GLU B . n +C 1 233 VAL 233 295 295 VAL VAL B . n +C 1 234 THR 234 296 296 THR THR B . n +C 1 235 LYS 235 297 297 LYS LYS B . n +C 1 236 ASN 236 298 298 ASN ASN B . n +C 1 237 GLU 237 299 299 GLU GLU B . n +C 1 238 ILE 238 300 300 ILE ILE B . n +C 1 239 LEU 239 301 301 LEU LEU B . n +C 1 240 GLN 240 302 302 GLN GLN B . n +C 1 241 SER 241 303 303 SER SER B . n +C 1 242 VAL 242 304 304 VAL VAL B . n +C 1 243 PHE 243 305 305 PHE PHE B . n +C 1 244 PHE 244 306 306 PHE PHE B . n +C 1 245 VAL 245 307 307 VAL VAL B . n +C 1 246 SER 246 308 308 SER SER B . n +C 1 247 PRO 247 309 309 PRO PRO B . n +C 1 248 ALA 248 310 310 ALA ALA B . n +C 1 249 SER 249 311 311 SER SER B . n +C 1 250 ASN 250 312 312 ASN ASN B . n +C 1 251 VAL 251 313 313 VAL VAL B . n +C 1 252 CYS 252 314 314 CYS CYS B . n +C 1 253 PHE 253 315 315 PHE PHE B . n +C 1 254 PHE 254 316 316 PHE PHE B . n +C 1 255 ALA 255 317 317 ALA ALA B . n +C 1 256 LYS 256 318 318 LYS LYS B . n +C 1 257 CYS 257 319 319 CYS CYS B . n +C 1 258 PRO 258 320 320 PRO PRO B . n +C 1 259 TYR 259 321 321 TYR TYR B . n +C 1 260 MET 260 322 322 MET MET B . n +C 1 261 CYS 261 323 323 CYS CYS B . n +C 1 262 LYS 262 324 324 LYS LYS B . n +C 1 263 THR 263 325 325 THR THR B . n +C 1 264 GLU 264 326 326 GLU GLU B . n +C 1 265 TYR 265 327 327 TYR TYR B . n +C 1 266 ALA 266 328 328 ALA ALA B . n +C 1 267 VAL 267 329 329 VAL VAL B . n +C 1 268 CYS 268 330 330 CYS CYS B . n +C 1 269 GLY 269 331 331 GLY GLY B . n +C 1 270 LYS 270 332 332 LYS LYS B . n +C 1 271 PRO 271 333 333 PRO PRO B . n +C 1 272 HIS 272 334 334 HIS HIS B . n +C 1 273 LEU 273 335 335 LEU LEU B . n +C 1 274 LEU 274 336 336 LEU LEU B . n +C 1 275 GLU 275 337 337 GLU GLU B . n +C 1 276 GLY 276 338 338 GLY GLY B . n +C 1 277 SER 277 339 339 SER SER B . n +C 1 278 LEU 278 340 340 LEU LEU B . n +C 1 279 SER 279 341 341 SER SER B . n +C 1 280 ALA 280 342 342 ALA ALA B . n +C 1 281 PHE 281 343 343 PHE PHE B . n +C 1 282 LEU 282 344 344 LEU LEU B . n +C 1 283 PRO 283 345 345 PRO PRO B . n +C 1 284 SER 284 346 346 SER SER B . n +C 1 285 LEU 285 347 347 LEU LEU B . n +C 1 286 ASN 286 348 348 ASN ASN B . n +C 1 287 LEU 287 349 349 LEU LEU B . n +C 1 288 ALA 288 350 350 ALA ALA B . n +C 1 289 PRO 289 351 351 PRO PRO B . n +C 1 290 ARG 290 352 352 ARG ARG B . n +C 1 291 LEU 291 353 353 LEU LEU B . n +C 1 292 SER 292 354 354 SER SER B . n +C 1 293 VAL 293 355 355 VAL VAL B . n +C 1 294 PRO 294 356 356 PRO PRO B . n +C 1 295 ASN 295 357 357 ASN ASN B . n +C 1 296 PRO 296 358 358 PRO PRO B . n +C 1 297 TRP 297 359 359 TRP TRP B . n +C 1 298 ILE 298 360 360 ILE ILE B . n +C 1 299 ARG 299 361 361 ARG ARG B . n +C 1 300 SER 300 362 362 SER SER B . n +C 1 301 TYR 301 363 363 TYR TYR B . n +C 1 302 THR 302 364 364 THR THR B . n +C 1 303 LEU 303 365 365 LEU LEU B . n +C 1 304 ALA 304 366 366 ALA ALA B . n +C 1 305 GLY 305 367 367 GLY GLY B . n +C 1 306 LYS 306 368 368 LYS LYS B . n +C 1 307 GLU 307 369 369 GLU GLU B . n +C 1 308 GLU 308 370 370 GLU GLU B . n +C 1 309 TRP 309 371 371 TRP TRP B . n +C 1 310 GLU 310 372 372 GLU GLU B . n +C 1 311 VAL 311 373 373 VAL VAL B . n +C 1 312 ASN 312 374 374 ASN ASN B . n +C 1 313 PRO 313 375 375 PRO PRO B . n +C 1 314 LEU 314 376 376 LEU LEU B . n +C 1 315 TYR 315 377 377 TYR TYR B . n +C 1 316 CYS 316 378 378 CYS CYS B . n +C 1 317 ASP 317 379 379 ASP ASP B . n +C 1 318 THR 318 380 380 THR THR B . n +C 1 319 VAL 319 381 381 VAL VAL B . n +C 1 320 LYS 320 382 382 LYS LYS B . n +C 1 321 GLN 321 383 383 GLN GLN B . n +C 1 322 ILE 322 384 384 ILE ILE B . n +C 1 323 TYR 323 385 385 TYR TYR B . n +C 1 324 PRO 324 386 386 PRO PRO B . n +C 1 325 TYR 325 387 387 TYR TYR B . n +C 1 326 ASN 326 388 388 ASN ASN B . n +C 1 327 ASN 327 389 389 ASN ASN B . n +C 1 328 SER 328 390 390 SER SER B . n +C 1 329 GLN 329 391 391 GLN GLN B . n +C 1 330 ARG 330 392 392 ARG ARG B . n +C 1 331 LEU 331 393 393 LEU LEU B . n +C 1 332 LEU 332 394 394 LEU LEU B . n +C 1 333 ASN 333 395 395 ASN ASN B . n +C 1 334 VAL 334 396 396 VAL VAL B . n +C 1 335 ILE 335 397 397 ILE ILE B . n +C 1 336 ASP 336 398 398 ASP ASP B . n +C 1 337 MET 337 399 399 MET MET B . n +C 1 338 ALA 338 400 400 ALA ALA B . n +C 1 339 ILE 339 401 401 ILE ILE B . n +C 1 340 PHE 340 402 402 PHE PHE B . n +C 1 341 ASP 341 403 403 ASP ASP B . n +C 1 342 PHE 342 404 404 PHE PHE B . n +C 1 343 LEU 343 405 405 LEU LEU B . n +C 1 344 ILE 344 406 406 ILE ILE B . n +C 1 345 GLY 345 407 407 GLY GLY B . n +C 1 346 ASN 346 408 408 ASN ASN B . n +C 1 347 MET 347 409 409 MET MET B . n +C 1 348 ASP 348 410 410 ASP ASP B . n +C 1 349 ARG 349 411 411 ARG ARG B . n +C 1 350 HIS 350 412 412 HIS HIS B . n +C 1 351 HIS 351 413 413 HIS HIS B . n +C 1 352 TYR 352 414 414 TYR TYR B . n +C 1 353 GLU 353 415 415 GLU GLU B . n +C 1 354 MET 354 416 416 MET MET B . n +C 1 355 PHE 355 417 417 PHE PHE B . n +C 1 356 THR 356 418 418 THR THR B . n +C 1 357 LYS 357 419 419 LYS LYS B . n +C 1 358 PHE 358 420 420 PHE PHE B . n +C 1 359 GLY 359 421 421 GLY GLY B . n +C 1 360 ASP 360 422 422 ASP ASP B . n +C 1 361 ASP 361 423 423 ASP ASP B . n +C 1 362 GLY 362 424 424 GLY GLY B . n +C 1 363 PHE 363 425 425 PHE PHE B . n +C 1 364 LEU 364 426 426 LEU LEU B . n +C 1 365 ILE 365 427 427 ILE ILE B . n +C 1 366 HIS 366 428 428 HIS HIS B . n +C 1 367 LEU 367 429 429 LEU LEU B . n +C 1 368 ASP 368 430 430 ASP ASP B . n +C 1 369 ASN 369 431 431 ASN ASN B . n +C 1 370 ALA 370 432 432 ALA ALA B . n +C 1 371 ARG 371 433 433 ARG ARG B . n +C 1 372 GLY 372 434 434 GLY GLY B . n +C 1 373 PHE 373 435 435 PHE PHE B . n +C 1 374 GLY 374 436 436 GLY GLY B . n +C 1 375 ARG 375 437 437 ARG ARG B . n +C 1 376 HIS 376 438 438 HIS HIS B . n +C 1 377 SER 377 439 439 SER SER B . n +C 1 378 HIS 378 440 440 HIS HIS B . n +C 1 379 ASP 379 441 441 ASP ASP B . n +C 1 380 GLU 380 442 442 GLU GLU B . n +C 1 381 ILE 381 443 443 ILE ILE B . n +C 1 382 SER 382 444 444 SER SER B . n +C 1 383 ILE 383 445 445 ILE ILE B . n +C 1 384 LEU 384 446 446 LEU LEU B . n +C 1 385 SER 385 447 447 SER SER B . n +C 1 386 PRO 386 448 448 PRO PRO B . n +C 1 387 LEU 387 449 449 LEU LEU B . n +C 1 388 SER 388 450 450 SER SER B . n +C 1 389 GLN 389 451 451 GLN GLN B . n +C 1 390 CYS 390 452 452 CYS CYS B . n +C 1 391 CYS 391 453 453 CYS CYS B . n +C 1 392 MET 392 454 454 MET MET B . n +C 1 393 ILE 393 455 455 ILE ILE B . n +C 1 394 LYS 394 456 456 LYS LYS B . n +C 1 395 LYS 395 457 457 LYS LYS B . n +C 1 396 LYS 396 458 458 LYS LYS B . n +C 1 397 THR 397 459 459 THR THR B . n +C 1 398 LEU 398 460 460 LEU LEU B . n +C 1 399 LEU 399 461 461 LEU LEU B . n +C 1 400 HIS 400 462 462 HIS HIS B . n +C 1 401 LEU 401 463 463 LEU LEU B . n +C 1 402 GLN 402 464 464 GLN GLN B . n +C 1 403 LEU 403 465 465 LEU LEU B . n +C 1 404 LEU 404 466 466 LEU LEU B . n +C 1 405 ALA 405 467 467 ALA ALA B . n +C 1 406 GLN 406 468 468 GLN GLN B . n +C 1 407 ALA 407 469 469 ALA ALA B . n +C 1 408 ASP 408 470 470 ASP ASP B . n +C 1 409 TYR 409 471 471 TYR TYR B . n +C 1 410 ARG 410 472 472 ARG ARG B . n +C 1 411 LEU 411 473 473 LEU LEU B . n +C 1 412 SER 412 474 474 SER SER B . n +C 1 413 ASP 413 475 475 ASP ASP B . n +C 1 414 VAL 414 476 476 VAL VAL B . n +C 1 415 MET 415 477 477 MET MET B . n +C 1 416 ARG 416 478 478 ARG ARG B . n +C 1 417 GLU 417 479 479 GLU GLU B . n +C 1 418 SER 418 480 480 SER SER B . n +C 1 419 LEU 419 481 481 LEU LEU B . n +C 1 420 LEU 420 482 482 LEU LEU B . n +C 1 421 GLU 421 483 483 GLU GLU B . n +C 1 422 ASP 422 484 484 ASP ASP B . n +C 1 423 GLN 423 485 485 GLN GLN B . n +C 1 424 LEU 424 486 486 LEU LEU B . n +C 1 425 SER 425 487 487 SER SER B . n +C 1 426 PRO 426 488 488 PRO PRO B . n +C 1 427 VAL 427 489 489 VAL VAL B . n +C 1 428 LEU 428 490 490 LEU LEU B . n +C 1 429 THR 429 491 491 THR THR B . n +C 1 430 GLU 430 492 492 GLU GLU B . n +C 1 431 PRO 431 493 493 PRO PRO B . n +C 1 432 HIS 432 494 494 HIS HIS B . n +C 1 433 LEU 433 495 495 LEU LEU B . n +C 1 434 LEU 434 496 496 LEU LEU B . n +C 1 435 ALA 435 497 497 ALA ALA B . n +C 1 436 LEU 436 498 498 LEU LEU B . n +C 1 437 ASP 437 499 499 ASP ASP B . n +C 1 438 ARG 438 500 500 ARG ARG B . n +C 1 439 ARG 439 501 501 ARG ARG B . n +C 1 440 LEU 440 502 502 LEU LEU B . n +C 1 441 GLN 441 503 503 GLN GLN B . n +C 1 442 THR 442 504 504 THR THR B . n +C 1 443 ILE 443 505 505 ILE ILE B . n +C 1 444 LEU 444 506 506 LEU LEU B . n +C 1 445 ARG 445 507 507 ARG ARG B . n +C 1 446 THR 446 508 508 THR THR B . n +C 1 447 VAL 447 509 509 VAL VAL B . n +C 1 448 GLU 448 510 510 GLU GLU B . n +C 1 449 GLY 449 511 511 GLY GLY B . n +C 1 450 CYS 450 512 512 CYS CYS B . n +C 1 451 ILE 451 513 513 ILE ILE B . n +C 1 452 VAL 452 514 514 VAL VAL B . n +C 1 453 ALA 453 515 515 ALA ALA B . n +C 1 454 HIS 454 516 516 HIS HIS B . n +C 1 455 GLY 455 517 517 GLY GLY B . n +C 1 456 GLN 456 518 518 GLN GLN B . n +C 1 457 GLN 457 519 519 GLN GLN B . n +C 1 458 SER 458 520 520 SER SER B . n +C 1 459 VAL 459 521 521 VAL VAL B . n +C 1 460 ILE 460 522 522 ILE ILE B . n +C 1 461 VAL 461 523 523 VAL VAL B . n +C 1 462 ASP 462 524 524 ASP ASP B . n +C 1 463 GLY 463 525 525 GLY GLY B . n +C 1 464 PRO 464 526 526 PRO PRO B . n +C 1 465 VAL 465 527 ? ? ? B . n +C 1 466 GLU 466 528 ? ? ? B . n +C 1 467 GLN 467 529 ? ? ? B . n +D 2 1 MET 1 1 ? ? ? D . n +D 2 2 ILE 2 2 ? ? ? D . n +D 2 3 LEU 3 3 ? ? ? D . n +D 2 4 PHE 4 4 ? ? ? D . n +D 2 5 ARG 5 5 ? ? ? D . n +D 2 6 LYS 6 6 ? ? ? D . n +D 2 7 PHE 7 7 ? ? ? D . n +D 2 8 ARG 8 8 ? ? ? D . n +D 2 9 VAL 9 9 ? ? ? D . n +D 2 10 LEU 10 10 ? ? ? D . n +D 2 11 ILE 11 11 ? ? ? D . n +D 2 12 LEU 12 12 ? ? ? D . n +D 2 13 THR 13 13 ? ? ? D . n +D 2 14 VAL 14 14 ? ? ? D . n +D 2 15 PHE 15 15 ? ? ? D . n +D 2 16 LEU 16 16 ? ? ? D . n +D 2 17 ILE 17 17 ? ? ? D . n +D 2 18 ALA 18 18 ? ? ? D . n +D 2 19 CYS 19 19 ? ? ? D . n +D 2 20 THR 20 20 ? ? ? D . n +D 2 21 MET 21 21 ? ? ? D . n +D 2 22 HIS 22 22 ? ? ? D . n +D 2 23 ILE 23 23 ? ? ? D . n +D 2 24 MET 24 24 ? ? ? D . n +D 2 25 ILE 25 25 ? ? ? D . n +D 2 26 ASP 26 26 ? ? ? D . n +D 2 27 LEU 27 27 ? ? ? D . n +D 2 28 LEU 28 28 ? ? ? D . n +D 2 29 PRO 29 29 ? ? ? D . n +D 2 30 LYS 30 30 ? ? ? D . n +D 2 31 LEU 31 31 ? ? ? D . n +D 2 32 GLU 32 32 ? ? ? D . n +D 2 33 LYS 33 33 ? ? ? D . n +D 2 34 ARG 34 34 ? ? ? D . n +D 2 35 ALA 35 35 ? ? ? D . n +D 2 36 ALA 36 36 ? ? ? D . n +D 2 37 GLY 37 37 ? ? ? D . n +D 2 38 SER 38 38 ? ? ? D . n +D 2 39 SER 39 39 ? ? ? D . n +D 2 40 SER 40 40 ? ? ? D . n +D 2 41 SER 41 41 ? ? ? D . n +D 2 42 ALA 42 42 ? ? ? D . n +D 2 43 GLY 43 43 ? ? ? D . n +D 2 44 GLY 44 44 ? ? ? D . n +D 2 45 GLY 45 45 ? ? ? D . n +D 2 46 SER 46 46 ? ? ? D . n +D 2 47 GLY 47 47 ? ? ? D . n +D 2 48 CYS 48 48 ? ? ? D . n +D 2 49 SER 49 49 ? ? ? D . n +D 2 50 CYS 50 50 ? ? ? D . n +D 2 51 ALA 51 51 ? ? ? D . n +D 2 52 HIS 52 52 ? ? ? D . n +D 2 53 THR 53 53 ? ? ? D . n +D 2 54 PRO 54 54 ? ? ? D . n +D 2 55 GLY 55 55 ? ? ? D . n +D 2 56 GLU 56 56 ? ? ? D . n +D 2 57 GLU 57 57 ? ? ? D . n +D 2 58 PRO 58 58 ? ? ? D . n +D 2 59 ARG 59 59 ? ? ? D . n +D 2 60 SER 60 60 ? ? ? D . n +D 2 61 TRP 61 61 ? ? ? D . n +D 2 62 GLY 62 62 ? ? ? D . n +D 2 63 LYS 63 63 ? ? ? D . n +D 2 64 GLN 64 64 ? ? ? D . n +D 2 65 ARG 65 65 ? ? ? D . n +D 2 66 ALA 66 66 ? ? ? D . n +D 2 67 ARG 67 67 ? ? ? D . n +D 2 68 ALA 68 68 ? ? ? D . n +D 2 69 ALA 69 69 ? ? ? D . n +D 2 70 ASP 70 70 ? ? ? D . n +D 2 71 PRO 71 71 ? ? ? D . n +D 2 72 GLY 72 72 ? ? ? D . n +D 2 73 TRP 73 73 ? ? ? D . n +D 2 74 PRO 74 74 ? ? ? D . n +D 2 75 ASN 75 75 ? ? ? D . n +D 2 76 LYS 76 76 ? ? ? D . n +D 2 77 HIS 77 77 ? ? ? D . n +D 2 78 SER 78 78 ? ? ? D . n +D 2 79 LEU 79 79 ? ? ? D . n +D 2 80 ARG 80 80 ? ? ? D . n +D 2 81 LEU 81 81 ? ? ? D . n +D 2 82 LEU 82 82 ? ? ? D . n +D 2 83 GLN 83 83 ? ? ? D . n +D 2 84 ASP 84 84 ? ? ? D . n +D 2 85 PHE 85 85 ? ? ? D . n +D 2 86 SER 86 86 ? ? ? D . n +D 2 87 ASN 87 87 ? ? ? D . n +D 2 88 GLU 88 88 ? ? ? D . n +D 2 89 PRO 89 89 ? ? ? D . n +D 2 90 ASN 90 90 ? ? ? D . n +D 2 91 SER 91 91 ? ? ? D . n +D 2 92 ASN 92 92 ? ? ? D . n +D 2 93 LEU 93 93 ? ? ? D . n +D 2 94 THR 94 94 ? ? ? D . n +D 2 95 SER 95 95 ? ? ? D . n +D 2 96 GLN 96 96 ? ? ? D . n +D 2 97 SER 97 97 ? ? ? D . n +D 2 98 ARG 98 98 ? ? ? D . n +D 2 99 GLU 99 99 ? ? ? D . n +D 2 100 LYS 100 100 ? ? ? D . n +D 2 101 VAL 101 101 ? ? ? D . n +D 2 102 THR 102 102 ? ? ? D . n +D 2 103 GLU 103 103 ? ? ? D . n +D 2 104 ARG 104 104 ? ? ? D . n +D 2 105 ALA 105 105 ? ? ? D . n +D 2 106 GLY 106 106 ? ? ? D . n +D 2 107 SER 107 107 ? ? ? D . n +D 2 108 GLU 108 108 ? ? ? D . n +D 2 109 LYS 109 109 ? ? ? D . n +D 2 110 GLN 110 110 ? ? ? D . n +D 2 111 GLY 111 111 ? ? ? D . n +D 2 112 SER 112 112 ? ? ? D . n +D 2 113 GLY 113 113 ? ? ? D . n +D 2 114 LYS 114 114 ? ? ? D . n +D 2 115 ARG 115 115 ? ? ? D . n +D 2 116 GLY 116 116 ? ? ? D . n +D 2 117 LEU 117 117 ? ? ? D . n +D 2 118 MET 118 118 ? ? ? D . n +D 2 119 ARG 119 119 ? ? ? D . n +D 2 120 GLU 120 120 ? ? ? D . n +D 2 121 ALA 121 121 ? ? ? D . n +D 2 122 ASP 122 122 ? ? ? D . n +D 2 123 SER 123 123 ? ? ? D . n +D 2 124 ARG 124 124 ? ? ? D . n +D 2 125 GLN 125 125 ? ? ? D . n +D 2 126 ARG 126 126 ? ? ? D . n +D 2 127 ARG 127 127 ? ? ? D . n +D 2 128 THR 128 128 ? ? ? D . n +D 2 129 ASP 129 129 ? ? ? D . n +D 2 130 VAL 130 130 ? ? ? D . n +D 2 131 ARG 131 131 ? ? ? D . n +D 2 132 VAL 132 132 ? ? ? D . n +D 2 133 SER 133 133 ? ? ? D . n +D 2 134 SER 134 134 134 SER SER D . n +D 2 135 VAL 135 135 135 VAL VAL D . n +D 2 136 LEU 136 136 136 LEU LEU D . n +D 2 137 GLN 137 137 137 GLN GLN D . n +D 2 138 SER 138 138 138 SER SER D . n +D 2 139 LEU 139 139 139 LEU LEU D . n +D 2 140 PHE 140 140 140 PHE PHE D . n +D 2 141 GLU 141 141 141 GLU GLU D . n +D 2 142 HIS 142 142 142 HIS HIS D . n +D 2 143 PRO 143 143 143 PRO PRO D . n +D 2 144 LEU 144 144 144 LEU LEU D . n +D 2 145 TYR 145 145 145 TYR TYR D . n +D 2 146 ARG 146 146 146 ARG ARG D . n +D 2 147 THR 147 147 147 THR THR D . n +D 2 148 VAL 148 148 148 VAL VAL D . n +D 2 149 LEU 149 149 149 LEU LEU D . n +D 2 150 PRO 150 150 150 PRO PRO D . n +D 2 151 ASP 151 151 151 ASP ASP D . n +D 2 152 LEU 152 152 152 LEU LEU D . n +D 2 153 THR 153 153 153 THR THR D . n +D 2 154 GLU 154 154 154 GLU GLU D . n +D 2 155 GLU 155 155 155 GLU GLU D . n +D 2 156 ASP 156 156 156 ASP ASP D . n +D 2 157 THR 157 157 157 THR THR D . n +D 2 158 LEU 158 158 158 LEU LEU D . n +D 2 159 PHE 159 159 159 PHE PHE D . n +D 2 160 ASN 160 160 160 ASN ASN D . n +D 2 161 LEU 161 161 161 LEU LEU D . n +D 2 162 ASN 162 162 162 ASN ASN D . n +D 2 163 ALA 163 163 163 ALA ALA D . n +D 2 164 GLU 164 164 164 GLU GLU D . n +D 2 165 ILE 165 165 165 ILE ILE D . n +D 2 166 ARG 166 166 166 ARG ARG D . n +D 2 167 LEU 167 167 167 LEU LEU D . n +D 2 168 TYR 168 168 168 TYR TYR D . n +D 2 169 PRO 169 169 169 PRO PRO D . n +D 2 170 LYS 170 170 170 LYS LYS D . n +D 2 171 ALA 171 171 171 ALA ALA D . n +D 2 172 ALA 172 172 ? ? ? D . n +D 2 173 GLY 173 173 ? ? ? D . n +D 2 174 GLN 174 174 ? ? ? D . n +D 2 175 GLN 175 175 ? ? ? D . n +D 2 176 GLU 176 176 ? ? ? D . n +D 2 177 TRP 177 177 ? ? ? D . n +D 2 178 HIS 178 178 ? ? ? D . n +D 2 179 ASN 179 179 ? ? ? D . n +D 2 180 GLU 180 180 ? ? ? D . n +D 2 181 GLY 181 181 ? ? ? D . n +D 2 182 ASN 182 182 ? ? ? D . n +D 2 183 VAL 183 183 ? ? ? D . n +D 2 184 GLU 184 184 ? ? ? D . n +D 2 185 GLU 185 185 ? ? ? D . n +D 2 186 GLU 186 186 ? ? ? D . n +D 2 187 GLU 187 187 ? ? ? D . n +D 2 188 PHE 188 188 ? ? ? D . n +D 2 189 SER 189 189 ? ? ? D . n +D 2 190 PRO 190 190 ? ? ? D . n +D 2 191 PRO 191 191 ? ? ? D . n +D 2 192 GLY 192 192 ? ? ? D . n +D 2 193 GLU 193 193 ? ? ? D . n +D 2 194 ALA 194 194 ? ? ? D . n +D 2 195 ASN 195 195 ? ? ? D . n +D 2 196 SER 196 196 ? ? ? D . n +D 2 197 GLU 197 197 197 GLU GLU D . n +D 2 198 SER 198 198 198 SER SER D . n +D 2 199 TYR 199 199 199 TYR TYR D . n +D 2 200 PRO 200 200 200 PRO PRO D . n +D 2 201 ASN 201 201 201 ASN ASN D . n +D 2 202 TRP 202 202 202 TRP TRP D . n +D 2 203 LEU 203 203 203 LEU LEU D . n +D 2 204 ARG 204 204 204 ARG ARG D . n +D 2 205 PHE 205 205 205 PHE PHE D . n +D 2 206 HIS 206 206 206 HIS HIS D . n +D 2 207 ILE 207 207 207 ILE ILE D . n +D 2 208 GLY 208 208 208 GLY GLY D . n +D 2 209 ILE 209 209 209 ILE ILE D . n +D 2 210 ASN 210 210 210 ASN ASN D . n +D 2 211 ARG 211 211 211 ARG ARG D . n +D 2 212 TYR 212 212 212 TYR TYR D . n +D 2 213 GLU 213 213 213 GLU GLU D . n +D 2 214 LEU 214 214 214 LEU LEU D . n +D 2 215 TYR 215 215 215 TYR TYR D . n +D 2 216 SER 216 216 216 SER SER D . n +D 2 217 ARG 217 217 217 ARG ARG D . n +D 2 218 HIS 218 218 218 HIS HIS D . n +D 2 219 ASN 219 219 219 ASN ASN D . n +D 2 220 PRO 220 220 220 PRO PRO D . n +D 2 221 VAL 221 221 221 VAL VAL D . n +D 2 222 ILE 222 222 222 ILE ILE D . n +D 2 223 ALA 223 223 223 ALA ALA D . n +D 2 224 ALA 224 224 224 ALA ALA D . n +D 2 225 LEU 225 225 225 LEU LEU D . n +D 2 226 LEU 226 226 226 LEU LEU D . n +D 2 227 ARG 227 227 227 ARG ARG D . n +D 2 228 ASP 228 228 228 ASP ASP D . n +D 2 229 LEU 229 229 229 LEU LEU D . n +D 2 230 LEU 230 230 230 LEU LEU D . n +D 2 231 SER 231 231 231 SER SER D . n +D 2 232 GLN 232 232 232 GLN GLN D . n +D 2 233 LYS 233 233 233 LYS LYS D . n +D 2 234 ILE 234 234 234 ILE ILE D . n +D 2 235 SER 235 235 235 SER SER D . n +D 2 236 SER 236 236 236 SER SER D . n +D 2 237 VAL 237 237 237 VAL VAL D . n +D 2 238 GLY 238 238 238 GLY GLY D . n +D 2 239 MET 239 239 239 MET MET D . n +D 2 240 LYS 240 240 240 LYS LYS D . n +D 2 241 SER 241 241 241 SER SER D . n +D 2 242 GLY 242 242 242 GLY GLY D . n +D 2 243 GLY 243 243 243 GLY GLY D . n +D 2 244 THR 244 244 244 THR THR D . n +D 2 245 GLN 245 245 245 GLN GLN D . n +D 2 246 LEU 246 246 246 LEU LEU D . n +D 2 247 LYS 247 247 247 LYS LYS D . n +D 2 248 LEU 248 248 248 LEU LEU D . n +D 2 249 ILE 249 249 249 ILE ILE D . n +D 2 250 MET 250 250 250 MET MET D . n +D 2 251 SER 251 251 251 SER SER D . n +D 2 252 PHE 252 252 252 PHE PHE D . n +D 2 253 GLN 253 253 253 GLN GLN D . n +D 2 254 ASN 254 254 254 ASN ASN D . n +D 2 255 TYR 255 255 255 TYR TYR D . n +D 2 256 GLY 256 256 256 GLY GLY D . n +D 2 257 GLN 257 257 257 GLN GLN D . n +D 2 258 ALA 258 258 258 ALA ALA D . n +D 2 259 LEU 259 259 259 LEU LEU D . n +D 2 260 PHE 260 260 260 PHE PHE D . n +D 2 261 LYS 261 261 261 LYS LYS D . n +D 2 262 PRO 262 262 262 PRO PRO D . n +D 2 263 MET 263 263 263 MET MET D . n +D 2 264 LYS 264 264 264 LYS LYS D . n +D 2 265 GLN 265 265 265 GLN GLN D . n +D 2 266 THR 266 266 266 THR THR D . n +D 2 267 ARG 267 267 267 ARG ARG D . n +D 2 268 GLU 268 268 268 GLU GLU D . n +D 2 269 GLN 269 269 269 GLN GLN D . n +D 2 270 GLU 270 270 270 GLU GLU D . n +D 2 271 THR 271 271 271 THR THR D . n +D 2 272 PRO 272 272 272 PRO PRO D . n +D 2 273 PRO 273 273 273 PRO PRO D . n +D 2 274 ASP 274 274 274 ASP ASP D . n +D 2 275 PHE 275 275 275 PHE PHE D . n +D 2 276 PHE 276 276 276 PHE PHE D . n +D 2 277 TYR 277 277 277 TYR TYR D . n +D 2 278 PHE 278 278 278 PHE PHE D . n +D 2 279 SER 279 279 279 SER SER D . n +D 2 280 ASP 280 280 280 ASP ASP D . n +D 2 281 PHE 281 281 281 PHE PHE D . n +D 2 282 GLU 282 282 282 GLU GLU D . n +D 2 283 ARG 283 283 283 ARG ARG D . n +D 2 284 HIS 284 284 284 HIS HIS D . n +D 2 285 ASN 285 285 285 ASN ASN D . n +D 2 286 ALA 286 286 286 ALA ALA D . n +D 2 287 GLU 287 287 287 GLU GLU D . n +D 2 288 ILE 288 288 288 ILE ILE D . n +D 2 289 ALA 289 289 289 ALA ALA D . n +D 2 290 ALA 290 290 290 ALA ALA D . n +D 2 291 PHE 291 291 291 PHE PHE D . n +D 2 292 HIS 292 292 292 HIS HIS D . n +D 2 293 LEU 293 293 293 LEU LEU D . n +D 2 294 ASP 294 294 294 ASP ASP D . n +D 2 295 ARG 295 295 295 ARG ARG D . n +D 2 296 ILE 296 296 296 ILE ILE D . n +D 2 297 LEU 297 297 297 LEU LEU D . n +D 2 298 ASP 298 298 298 ASP ASP D . n +D 2 299 PHE 299 299 299 PHE PHE D . n +D 2 300 ARG 300 300 300 ARG ARG D . n +D 2 301 ARG 301 301 301 ARG ARG D . n +D 2 302 VAL 302 302 302 VAL VAL D . n +D 2 303 PRO 303 303 303 PRO PRO D . n +D 2 304 PRO 304 304 304 PRO PRO D . n +D 2 305 VAL 305 305 305 VAL VAL D . n +D 2 306 ALA 306 306 306 ALA ALA D . n +D 2 307 GLY 307 307 307 GLY GLY D . n +D 2 308 ARG 308 308 308 ARG ARG D . n +D 2 309 LEU 309 309 309 LEU LEU D . n +D 2 310 VAL 310 310 310 VAL VAL D . n +D 2 311 ASN 311 311 311 ASN ASN D . n +D 2 312 MET 312 312 312 MET MET D . n +D 2 313 THR 313 313 313 THR THR D . n +D 2 314 ARG 314 314 314 ARG ARG D . n +D 2 315 GLU 315 315 315 GLU GLU D . n +D 2 316 ILE 316 316 316 ILE ILE D . n +D 2 317 ARG 317 317 317 ARG ARG D . n +D 2 318 ASP 318 318 318 ASP ASP D . n +D 2 319 VAL 319 319 319 VAL VAL D . n +D 2 320 THR 320 320 320 THR THR D . n +D 2 321 ARG 321 321 321 ARG ARG D . n +D 2 322 ASP 322 322 322 ASP ASP D . n +D 2 323 LYS 323 323 323 LYS LYS D . n +D 2 324 LYS 324 324 324 LYS LYS D . n +D 2 325 LEU 325 325 325 LEU LEU D . n +D 2 326 TRP 326 326 326 TRP TRP D . n +D 2 327 ARG 327 327 327 ARG ARG D . n +D 2 328 THR 328 328 328 THR THR D . n +D 2 329 PHE 329 329 329 PHE PHE D . n +D 2 330 PHE 330 330 330 PHE PHE D . n +D 2 331 VAL 331 331 331 VAL VAL D . n +D 2 332 SER 332 332 332 SER SER D . n +D 2 333 PRO 333 333 333 PRO PRO D . n +D 2 334 ALA 334 334 334 ALA ALA D . n +D 2 335 ASN 335 335 335 ASN ASN D . n +D 2 336 ASN 336 336 336 ASN ASN D . n +D 2 337 ILE 337 337 337 ILE ILE D . n +D 2 338 CYS 338 338 338 CYS CYS D . n +D 2 339 PHE 339 339 339 PHE PHE D . n +D 2 340 TYR 340 340 340 TYR TYR D . n +D 2 341 GLY 341 341 341 GLY GLY D . n +D 2 342 GLU 342 342 342 GLU GLU D . n +D 2 343 CYS 343 343 343 CYS CYS D . n +D 2 344 SER 344 344 344 SER SER D . n +D 2 345 TYR 345 345 345 TYR TYR D . n +D 2 346 TYR 346 346 346 TYR TYR D . n +D 2 347 CYS 347 347 347 CYS CYS D . n +D 2 348 SER 348 348 348 SER SER D . n +D 2 349 THR 349 349 349 THR THR D . n +D 2 350 GLU 350 350 350 GLU GLU D . n +D 2 351 HIS 351 351 351 HIS HIS D . n +D 2 352 ALA 352 352 352 ALA ALA D . n +D 2 353 LEU 353 353 353 LEU LEU D . n +D 2 354 CYS 354 354 354 CYS CYS D . n +D 2 355 GLY 355 355 355 GLY GLY D . n +D 2 356 LYS 356 356 356 LYS LYS D . n +D 2 357 PRO 357 357 357 PRO PRO D . n +D 2 358 ASP 358 358 358 ASP ASP D . n +D 2 359 GLN 359 359 359 GLN GLN D . n +D 2 360 ILE 360 360 360 ILE ILE D . n +D 2 361 GLU 361 361 361 GLU GLU D . n +D 2 362 GLY 362 362 362 GLY GLY D . n +D 2 363 SER 363 363 363 SER SER D . n +D 2 364 LEU 364 364 364 LEU LEU D . n +D 2 365 ALA 365 365 365 ALA ALA D . n +D 2 366 ALA 366 366 366 ALA ALA D . n +D 2 367 PHE 367 367 367 PHE PHE D . n +D 2 368 LEU 368 368 368 LEU LEU D . n +D 2 369 PRO 369 369 369 PRO PRO D . n +D 2 370 ASP 370 370 370 ASP ASP D . n +D 2 371 LEU 371 371 371 LEU LEU D . n +D 2 372 ALA 372 372 372 ALA ALA D . n +D 2 373 LEU 373 373 373 LEU LEU D . n +D 2 374 ALA 374 374 374 ALA ALA D . n +D 2 375 LYS 375 375 375 LYS LYS D . n +D 2 376 ARG 376 376 376 ARG ARG D . n +D 2 377 LYS 377 377 377 LYS LYS D . n +D 2 378 THR 378 378 378 THR THR D . n +D 2 379 TRP 379 379 379 TRP TRP D . n +D 2 380 ARG 380 380 380 ARG ARG D . n +D 2 381 ASN 381 381 381 ASN ASN D . n +D 2 382 PRO 382 382 382 PRO PRO D . n +D 2 383 TRP 383 383 383 TRP TRP D . n +D 2 384 ARG 384 384 384 ARG ARG D . n +D 2 385 ARG 385 385 385 ARG ARG D . n +D 2 386 SER 386 386 386 SER SER D . n +D 2 387 TYR 387 387 387 TYR TYR D . n +D 2 388 HIS 388 388 388 HIS HIS D . n +D 2 389 LYS 389 389 389 LYS LYS D . n +D 2 390 ARG 390 390 390 ARG ARG D . n +D 2 391 LYS 391 391 391 LYS LYS D . n +D 2 392 LYS 392 392 392 LYS LYS D . n +D 2 393 ALA 393 393 393 ALA ALA D . n +D 2 394 GLU 394 394 394 GLU GLU D . n +D 2 395 TRP 395 395 395 TRP TRP D . n +D 2 396 GLU 396 396 396 GLU GLU D . n +D 2 397 VAL 397 397 397 VAL VAL D . n +D 2 398 ASP 398 398 398 ASP ASP D . n +D 2 399 PRO 399 399 399 PRO PRO D . n +D 2 400 ASP 400 400 400 ASP ASP D . n +D 2 401 TYR 401 401 401 TYR TYR D . n +D 2 402 CYS 402 402 402 CYS CYS D . n +D 2 403 ASP 403 403 403 ASP ASP D . n +D 2 404 GLU 404 404 404 GLU GLU D . n +D 2 405 VAL 405 405 405 VAL VAL D . n +D 2 406 LYS 406 406 406 LYS LYS D . n +D 2 407 GLN 407 407 407 GLN GLN D . n +D 2 408 THR 408 408 408 THR THR D . n +D 2 409 PRO 409 409 409 PRO PRO D . n +D 2 410 PRO 410 410 410 PRO PRO D . n +D 2 411 TYR 411 411 411 TYR TYR D . n +D 2 412 ASP 412 412 412 ASP ASP D . n +D 2 413 ARG 413 413 413 ARG ARG D . n +D 2 414 GLY 414 414 414 GLY GLY D . n +D 2 415 THR 415 415 415 THR THR D . n +D 2 416 ARG 416 416 416 ARG ARG D . n +D 2 417 LEU 417 417 417 LEU LEU D . n +D 2 418 LEU 418 418 418 LEU LEU D . n +D 2 419 ASP 419 419 419 ASP ASP D . n +D 2 420 ILE 420 420 420 ILE ILE D . n +D 2 421 MET 421 421 421 MET MET D . n +D 2 422 ASP 422 422 422 ASP ASP D . n +D 2 423 MET 423 423 423 MET MET D . n +D 2 424 THR 424 424 424 THR THR D . n +D 2 425 ILE 425 425 425 ILE ILE D . n +D 2 426 PHE 426 426 426 PHE PHE D . n +D 2 427 ASP 427 427 427 ASP ASP D . n +D 2 428 PHE 428 428 428 PHE PHE D . n +D 2 429 LEU 429 429 429 LEU LEU D . n +D 2 430 MET 430 430 430 MET MET D . n +D 2 431 GLY 431 431 431 GLY GLY D . n +D 2 432 ASN 432 432 432 ASN ASN D . n +D 2 433 MET 433 433 433 MET MET D . n +D 2 434 ASP 434 434 434 ASP ASP D . n +D 2 435 ARG 435 435 435 ARG ARG D . n +D 2 436 HIS 436 436 436 HIS HIS D . n +D 2 437 HIS 437 437 437 HIS HIS D . n +D 2 438 TYR 438 438 438 TYR TYR D . n +D 2 439 GLU 439 439 439 GLU GLU D . n +D 2 440 THR 440 440 440 THR THR D . n +D 2 441 PHE 441 441 441 PHE PHE D . n +D 2 442 GLU 442 442 442 GLU GLU D . n +D 2 443 LYS 443 443 443 LYS LYS D . n +D 2 444 PHE 444 444 444 PHE PHE D . n +D 2 445 GLY 445 445 445 GLY GLY D . n +D 2 446 ASN 446 446 446 ASN ASN D . n +D 2 447 ASP 447 447 447 ASP ASP D . n +D 2 448 THR 448 448 448 THR THR D . n +D 2 449 PHE 449 449 449 PHE PHE D . n +D 2 450 ILE 450 450 450 ILE ILE D . n +D 2 451 ILE 451 451 451 ILE ILE D . n +D 2 452 HIS 452 452 452 HIS HIS D . n +D 2 453 LEU 453 453 453 LEU LEU D . n +D 2 454 ASP 454 454 454 ASP ASP D . n +D 2 455 ASN 455 455 455 ASN ASN D . n +D 2 456 GLY 456 456 456 GLY GLY D . n +D 2 457 ARG 457 457 457 ARG ARG D . n +D 2 458 GLY 458 458 458 GLY GLY D . n +D 2 459 PHE 459 459 459 PHE PHE D . n +D 2 460 GLY 460 460 460 GLY GLY D . n +D 2 461 LYS 461 461 461 LYS LYS D . n +D 2 462 HIS 462 462 462 HIS HIS D . n +D 2 463 SER 463 463 463 SER SER D . n +D 2 464 HIS 464 464 464 HIS HIS D . n +D 2 465 ASP 465 465 465 ASP ASP D . n +D 2 466 GLU 466 466 466 GLU GLU D . n +D 2 467 MET 467 467 467 MET MET D . n +D 2 468 SER 468 468 468 SER SER D . n +D 2 469 ILE 469 469 469 ILE ILE D . n +D 2 470 LEU 470 470 470 LEU LEU D . n +D 2 471 VAL 471 471 471 VAL VAL D . n +D 2 472 PRO 472 472 472 PRO PRO D . n +D 2 473 LEU 473 473 473 LEU LEU D . n +D 2 474 THR 474 474 474 THR THR D . n +D 2 475 GLN 475 475 475 GLN GLN D . n +D 2 476 CYS 476 476 476 CYS CYS D . n +D 2 477 CYS 477 477 477 CYS CYS D . n +D 2 478 ARG 478 478 478 ARG ARG D . n +D 2 479 VAL 479 479 479 VAL VAL D . n +D 2 480 LYS 480 480 480 LYS LYS D . n +D 2 481 ARG 481 481 481 ARG ARG D . n +D 2 482 SER 482 482 482 SER SER D . n +D 2 483 THR 483 483 483 THR THR D . n +D 2 484 TYR 484 484 484 TYR TYR D . n +D 2 485 LEU 485 485 485 LEU LEU D . n +D 2 486 ARG 486 486 486 ARG ARG D . n +D 2 487 LEU 487 487 487 LEU LEU D . n +D 2 488 GLN 488 488 488 GLN GLN D . n +D 2 489 LEU 489 489 489 LEU LEU D . n +D 2 490 LEU 490 490 490 LEU LEU D . n +D 2 491 ALA 491 491 491 ALA ALA D . n +D 2 492 LYS 492 492 492 LYS LYS D . n +D 2 493 GLU 493 493 493 GLU GLU D . n +D 2 494 GLU 494 494 494 GLU GLU D . n +D 2 495 TYR 495 495 495 TYR TYR D . n +D 2 496 LYS 496 496 496 LYS LYS D . n +D 2 497 LEU 497 497 497 LEU LEU D . n +D 2 498 SER 498 498 498 SER SER D . n +D 2 499 SER 499 499 499 SER SER D . n +D 2 500 LEU 500 500 500 LEU LEU D . n +D 2 501 MET 501 501 501 MET MET D . n +D 2 502 GLU 502 502 502 GLU GLU D . n +D 2 503 GLU 503 503 503 GLU GLU D . n +D 2 504 SER 504 504 504 SER SER D . n +D 2 505 LEU 505 505 505 LEU LEU D . n +D 2 506 LEU 506 506 506 LEU LEU D . n +D 2 507 GLN 507 507 507 GLN GLN D . n +D 2 508 ASP 508 508 508 ASP ASP D . n +D 2 509 ARG 509 509 509 ARG ARG D . n +D 2 510 LEU 510 510 510 LEU LEU D . n +D 2 511 VAL 511 511 511 VAL VAL D . n +D 2 512 PRO 512 512 512 PRO PRO D . n +D 2 513 VAL 513 513 513 VAL VAL D . n +D 2 514 LEU 514 514 514 LEU LEU D . n +D 2 515 ILE 515 515 515 ILE ILE D . n +D 2 516 LYS 516 516 516 LYS LYS D . n +D 2 517 PRO 517 517 517 PRO PRO D . n +D 2 518 HIS 518 518 518 HIS HIS D . n +D 2 519 LEU 519 519 519 LEU LEU D . n +D 2 520 GLU 520 520 520 GLU GLU D . n +D 2 521 ALA 521 521 521 ALA ALA D . n +D 2 522 LEU 522 522 522 LEU LEU D . n +D 2 523 ASP 523 523 523 ASP ASP D . n +D 2 524 ARG 524 524 524 ARG ARG D . n +D 2 525 ARG 525 525 525 ARG ARG D . n +D 2 526 LEU 526 526 526 LEU LEU D . n +D 2 527 ARG 527 527 527 ARG ARG D . n +D 2 528 LEU 528 528 528 LEU LEU D . n +D 2 529 VAL 529 529 529 VAL VAL D . n +D 2 530 LEU 530 530 530 LEU LEU D . n +D 2 531 LYS 531 531 531 LYS LYS D . n +D 2 532 VAL 532 532 532 VAL VAL D . n +D 2 533 LEU 533 533 533 LEU LEU D . n +D 2 534 SER 534 534 534 SER SER D . n +D 2 535 ASP 535 535 535 ASP ASP D . n +D 2 536 CYS 536 536 536 CYS CYS D . n +D 2 537 VAL 537 537 537 VAL VAL D . n +D 2 538 GLU 538 538 538 GLU GLU D . n +D 2 539 LYS 539 539 539 LYS LYS D . n +D 2 540 ASP 540 540 540 ASP ASP D . n +D 2 541 GLY 541 541 541 GLY GLY D . n +D 2 542 PHE 542 542 542 PHE PHE D . n +D 2 543 SER 543 543 543 SER SER D . n +D 2 544 ALA 544 544 544 ALA ALA D . n +D 2 545 VAL 545 545 545 VAL VAL D . n +D 2 546 VAL 546 546 546 VAL VAL D . n +D 2 547 GLU 547 547 547 GLU GLU D . n +D 2 548 ASN 548 548 548 ASN ASN D . n +D 2 549 ASP 549 549 549 ASP ASP D . n +D 2 550 LEU 550 550 550 LEU LEU D . n +D 2 551 ASP 551 551 551 ASP ASP D . n +D 2 552 GLY 552 552 552 GLY GLY D . n +D 2 553 GLN 553 553 ? ? ? D . n +D 2 554 PRO 554 554 ? ? ? D . n +D 2 555 SER 555 555 ? ? ? D . n +D 2 556 VAL 556 556 ? ? ? D . n +D 2 557 HIS 557 557 ? ? ? D . n +D 2 558 GLY 558 558 ? ? ? D . n +D 2 559 GLY 559 559 ? ? ? D . n +D 2 560 ARG 560 560 ? ? ? D . n +# +loop_ +_pdbx_nonpoly_scheme.asym_id +_pdbx_nonpoly_scheme.entity_id +_pdbx_nonpoly_scheme.mon_id +_pdbx_nonpoly_scheme.ndb_seq_num +_pdbx_nonpoly_scheme.pdb_seq_num +_pdbx_nonpoly_scheme.auth_seq_num +_pdbx_nonpoly_scheme.pdb_mon_id +_pdbx_nonpoly_scheme.auth_mon_id +_pdbx_nonpoly_scheme.pdb_strand_id +_pdbx_nonpoly_scheme.pdb_ins_code +E 3 ATP 1 701 701 ATP ATP A . +F 3 ATP 1 701 701 ATP ATP B . +# +_pdbx_struct_assembly.id 1 +_pdbx_struct_assembly.details author_and_software_defined_assembly +_pdbx_struct_assembly.method_details PISA +_pdbx_struct_assembly.oligomeric_details tetrameric +_pdbx_struct_assembly.oligomeric_count 4 +# +_pdbx_struct_assembly_gen.assembly_id 1 +_pdbx_struct_assembly_gen.oper_expression 1 +_pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F +# +loop_ +_pdbx_struct_assembly_prop.biol_id +_pdbx_struct_assembly_prop.type +_pdbx_struct_assembly_prop.value +_pdbx_struct_assembly_prop.details +1 'ABSA (A^2)' 9320 ? +1 MORE -36 ? +1 'SSA (A^2)' 69550 ? +# +_pdbx_struct_oper_list.id 1 +_pdbx_struct_oper_list.type 'identity operation' +_pdbx_struct_oper_list.name 1_555 +_pdbx_struct_oper_list.symmetry_operation x,y,z +_pdbx_struct_oper_list.matrix[1][1] 1.0000000000 +_pdbx_struct_oper_list.matrix[1][2] 0.0000000000 +_pdbx_struct_oper_list.matrix[1][3] 0.0000000000 +_pdbx_struct_oper_list.vector[1] 0.0000000000 +_pdbx_struct_oper_list.matrix[2][1] 0.0000000000 +_pdbx_struct_oper_list.matrix[2][2] 1.0000000000 +_pdbx_struct_oper_list.matrix[2][3] 0.0000000000 +_pdbx_struct_oper_list.vector[2] 0.0000000000 +_pdbx_struct_oper_list.matrix[3][1] 0.0000000000 +_pdbx_struct_oper_list.matrix[3][2] 0.0000000000 +_pdbx_struct_oper_list.matrix[3][3] 1.0000000000 +_pdbx_struct_oper_list.vector[3] 0.0000000000 +# +loop_ +_pdbx_audit_revision_history.ordinal +_pdbx_audit_revision_history.data_content_type +_pdbx_audit_revision_history.major_revision +_pdbx_audit_revision_history.minor_revision +_pdbx_audit_revision_history.revision_date +1 'Structure model' 1 0 2018-04-11 +2 'Structure model' 1 1 2018-04-25 +# +_pdbx_audit_revision_details.ordinal 1 +_pdbx_audit_revision_details.revision_ordinal 1 +_pdbx_audit_revision_details.data_content_type 'Structure model' +_pdbx_audit_revision_details.provider repository +_pdbx_audit_revision_details.type 'Initial release' +_pdbx_audit_revision_details.description ? +# +loop_ +_pdbx_audit_revision_group.ordinal +_pdbx_audit_revision_group.revision_ordinal +_pdbx_audit_revision_group.data_content_type +_pdbx_audit_revision_group.group +1 2 'Structure model' 'Data collection' +2 2 'Structure model' 'Database references' +3 2 'Structure model' 'Source and taxonomy' +4 2 'Structure model' 'Structure summary' +# +loop_ +_pdbx_audit_revision_category.ordinal +_pdbx_audit_revision_category.revision_ordinal +_pdbx_audit_revision_category.data_content_type +_pdbx_audit_revision_category.category +1 2 'Structure model' entity +2 2 'Structure model' entity_name_com +3 2 'Structure model' entity_src_gen +4 2 'Structure model' struct_ref +5 2 'Structure model' struct_ref_seq +6 2 'Structure model' struct_ref_seq_dif +# +loop_ +_pdbx_audit_revision_item.ordinal +_pdbx_audit_revision_item.revision_ordinal +_pdbx_audit_revision_item.data_content_type +_pdbx_audit_revision_item.item +1 2 'Structure model' '_entity.pdbx_description' +2 2 'Structure model' '_entity.pdbx_mutation' +3 2 'Structure model' '_entity_src_gen.gene_src_common_name' +4 2 'Structure model' '_entity_src_gen.pdbx_gene_src_gene' +5 2 'Structure model' '_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id' +6 2 'Structure model' '_entity_src_gen.pdbx_gene_src_scientific_name' +7 2 'Structure model' '_struct_ref.db_code' +8 2 'Structure model' '_struct_ref.db_name' +9 2 'Structure model' '_struct_ref.pdbx_db_accession' +10 2 'Structure model' '_struct_ref.pdbx_seq_one_letter_code' +11 2 'Structure model' '_struct_ref_seq.pdbx_db_accession' +# +loop_ +_software.citation_id +_software.classification +_software.compiler_name +_software.compiler_version +_software.contact_author +_software.contact_author_email +_software.date +_software.description +_software.dependencies +_software.hardware +_software.language +_software.location +_software.mods +_software.name +_software.os +_software.os_version +_software.type +_software.version +_software.pdbx_ordinal +? refinement ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.11.1_2575 1 +? 'data processing' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? . 2 +? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? . 3 +? phasing ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? . 4 +# +loop_ +_pdbx_validate_torsion.id +_pdbx_validate_torsion.PDB_model_num +_pdbx_validate_torsion.auth_comp_id +_pdbx_validate_torsion.auth_asym_id +_pdbx_validate_torsion.auth_seq_id +_pdbx_validate_torsion.PDB_ins_code +_pdbx_validate_torsion.label_alt_id +_pdbx_validate_torsion.phi +_pdbx_validate_torsion.psi +1 1 SER A 90 ? ? 59.08 86.89 +2 1 TYR A 101 ? ? -84.21 33.52 +3 1 ASN A 102 ? ? -149.38 -20.34 +4 1 ALA A 112 ? ? 56.98 -69.52 +5 1 ARG A 135 ? ? -70.49 -84.04 +6 1 ARG A 136 ? ? -18.11 -44.14 +7 1 SER A 199 ? ? 66.81 163.42 +8 1 GLN A 200 ? ? -73.58 -162.61 +9 1 ASP A 201 ? ? 64.73 -43.90 +10 1 GLU A 202 ? ? -84.59 -159.36 +11 1 LYS A 203 ? ? 62.48 -52.54 +12 1 LEU A 206 ? ? 63.18 -70.00 +13 1 ALA A 208 ? ? -159.64 73.71 +14 1 VAL A 215 ? ? -108.73 73.99 +15 1 VAL A 220 ? ? -97.91 43.72 +16 1 PHE A 231 ? ? 78.77 -10.25 +17 1 ASP A 250 ? ? 81.85 10.36 +18 1 PHE A 257 ? ? -73.54 -166.18 +19 1 ILE A 292 ? ? -129.86 -59.96 +20 1 TYR A 327 ? ? -103.83 -166.79 +21 1 SER A 390 ? ? 59.20 19.41 +22 1 TYR A 471 ? ? -141.17 52.28 +23 1 ASP A 524 ? ? -83.15 46.66 +24 1 THR C 147 ? ? -59.14 105.37 +25 1 PRO C 150 ? ? -57.94 172.89 +26 1 THR C 153 ? ? -170.43 149.54 +27 1 LEU C 161 ? ? -5.20 -48.28 +28 1 ASN C 162 ? ? -59.85 -9.21 +29 1 ALA C 171 ? ? 62.77 166.78 +30 1 GLU C 197 ? ? -88.40 46.61 +31 1 TYR C 212 ? ? -91.01 -78.48 +32 1 HIS C 218 ? ? -117.25 69.20 +33 1 TYR C 255 ? ? 64.06 -4.02 +34 1 LYS C 264 ? ? 71.83 -41.28 +35 1 ILE C 316 ? ? -126.73 -66.54 +36 1 ARG C 327 ? ? -69.23 1.11 +37 1 CYS C 343 ? ? -93.49 -128.91 +38 1 SER C 344 ? ? -137.26 -34.38 +39 1 CYS C 347 ? ? -114.66 69.87 +40 1 ASP C 358 ? ? -153.57 39.47 +41 1 GLU C 361 ? ? 71.53 147.47 +42 1 LEU C 371 ? ? -59.50 -8.22 +43 1 ALA C 374 ? ? -154.93 61.34 +44 1 ARG C 390 ? ? 71.93 -56.97 +45 1 LYS C 392 ? ? -79.79 -167.91 +46 1 ARG C 413 ? ? -144.00 -155.21 +47 1 THR C 415 ? ? 77.36 -54.26 +48 1 LEU C 417 ? ? 62.25 -58.39 +49 1 THR C 440 ? ? -137.50 -144.35 +50 1 GLU C 442 ? ? 59.94 -64.88 +51 1 TYR C 495 ? ? -110.42 -79.88 +52 1 LYS C 496 ? ? 59.54 175.38 +53 1 ARG C 509 ? ? -71.49 39.86 +54 1 LEU C 510 ? ? -143.26 -3.91 +55 1 SER C 543 ? ? 63.83 -30.84 +56 1 SER B 90 ? ? 60.41 84.04 +57 1 TYR B 101 ? ? -85.14 34.34 +58 1 ASN B 102 ? ? -149.46 -18.95 +59 1 ALA B 112 ? ? 59.46 -69.00 +60 1 SER B 199 ? ? 67.14 163.61 +61 1 GLN B 200 ? ? -73.77 -162.56 +62 1 ASP B 201 ? ? 64.63 -44.83 +63 1 LYS B 203 ? ? 63.72 -53.31 +64 1 LEU B 206 ? ? 63.49 -69.04 +65 1 ALA B 208 ? ? -159.94 73.83 +66 1 VAL B 215 ? ? -108.10 72.88 +67 1 SER B 218 ? ? -74.10 20.20 +68 1 VAL B 220 ? ? -98.32 44.90 +69 1 PHE B 231 ? ? 80.00 -10.20 +70 1 ASP B 250 ? ? 82.29 10.95 +71 1 PHE B 257 ? ? -74.62 -166.21 +72 1 ILE B 292 ? ? -128.05 -62.40 +73 1 TYR B 327 ? ? -103.49 -166.70 +74 1 TRP B 359 ? ? -116.67 50.97 +75 1 SER B 390 ? ? 58.40 19.94 +76 1 TYR B 471 ? ? -140.53 50.80 +77 1 ASP B 524 ? ? -82.44 46.90 +78 1 THR D 147 ? ? -59.41 102.53 +79 1 PRO D 150 ? ? -57.88 171.58 +80 1 LEU D 161 ? ? -16.83 -43.12 +81 1 TYR D 212 ? ? -91.58 -77.40 +82 1 HIS D 218 ? ? -116.56 67.32 +83 1 TYR D 255 ? ? 65.19 -3.60 +84 1 LYS D 264 ? ? 72.17 -40.73 +85 1 ILE D 316 ? ? -125.64 -66.91 +86 1 ARG D 327 ? ? -69.20 2.34 +87 1 CYS D 343 ? ? -92.22 -128.54 +88 1 SER D 344 ? ? -138.17 -34.08 +89 1 CYS D 347 ? ? -116.86 70.63 +90 1 ASP D 358 ? ? -153.15 39.69 +91 1 GLU D 361 ? ? 72.06 146.67 +92 1 LEU D 371 ? ? -59.90 -7.88 +93 1 ALA D 374 ? ? -154.59 59.90 +94 1 ARG D 390 ? ? 71.76 -56.56 +95 1 LYS D 392 ? ? -79.91 -167.96 +96 1 ARG D 413 ? ? -143.72 -156.00 +97 1 THR D 415 ? ? 76.90 -52.73 +98 1 LEU D 417 ? ? 62.15 -58.47 +99 1 THR D 440 ? ? -135.91 -143.42 +100 1 GLU D 442 ? ? 59.73 -63.77 +101 1 TYR D 495 ? ? -109.78 -80.24 +102 1 LYS D 496 ? ? 59.53 174.07 +103 1 ARG D 509 ? ? -70.59 41.09 +104 1 LEU D 510 ? ? -144.01 -1.42 +105 1 SER D 543 ? ? 62.92 -31.62 +106 1 ASP D 551 ? ? -62.73 87.75 +# +_pdbx_validate_peptide_omega.id 1 +_pdbx_validate_peptide_omega.PDB_model_num 1 +_pdbx_validate_peptide_omega.auth_comp_id_1 ASP +_pdbx_validate_peptide_omega.auth_asym_id_1 B +_pdbx_validate_peptide_omega.auth_seq_id_1 201 +_pdbx_validate_peptide_omega.PDB_ins_code_1 ? +_pdbx_validate_peptide_omega.label_alt_id_1 ? +_pdbx_validate_peptide_omega.auth_comp_id_2 GLU +_pdbx_validate_peptide_omega.auth_asym_id_2 B +_pdbx_validate_peptide_omega.auth_seq_id_2 202 +_pdbx_validate_peptide_omega.PDB_ins_code_2 ? +_pdbx_validate_peptide_omega.label_alt_id_2 ? +_pdbx_validate_peptide_omega.omega 149.52 +# +loop_ +_pdbx_unobs_or_zero_occ_residues.id +_pdbx_unobs_or_zero_occ_residues.PDB_model_num +_pdbx_unobs_or_zero_occ_residues.polymer_flag +_pdbx_unobs_or_zero_occ_residues.occupancy_flag +_pdbx_unobs_or_zero_occ_residues.auth_asym_id +_pdbx_unobs_or_zero_occ_residues.auth_comp_id +_pdbx_unobs_or_zero_occ_residues.auth_seq_id +_pdbx_unobs_or_zero_occ_residues.PDB_ins_code +_pdbx_unobs_or_zero_occ_residues.label_asym_id +_pdbx_unobs_or_zero_occ_residues.label_comp_id +_pdbx_unobs_or_zero_occ_residues.label_seq_id +1 1 Y 1 A ASP 63 ? A ASP 1 +2 1 Y 1 A PRO 64 ? A PRO 2 +3 1 Y 1 A GLY 65 ? A GLY 3 +4 1 Y 1 A THR 66 ? A THR 4 +5 1 Y 1 A ILE 67 ? A ILE 5 +6 1 Y 1 A VAL 68 ? A VAL 6 +7 1 Y 1 A HIS 69 ? A HIS 7 +8 1 Y 1 A ASN 70 ? A ASN 8 +9 1 Y 1 A PHE 71 ? A PHE 9 +10 1 Y 1 A SER 72 ? A SER 10 +11 1 Y 1 A ARG 73 ? A ARG 11 +12 1 Y 1 A THR 74 ? A THR 12 +13 1 Y 1 A GLU 75 ? A GLU 13 +14 1 Y 1 A PRO 76 ? A PRO 14 +15 1 Y 1 A ARG 77 ? A ARG 15 +16 1 Y 1 A THR 78 ? A THR 16 +17 1 Y 1 A GLU 79 ? A GLU 17 +18 1 Y 1 A PRO 80 ? A PRO 18 +19 1 Y 1 A ALA 81 ? A ALA 19 +20 1 Y 1 A GLY 82 ? A GLY 20 +21 1 Y 1 A GLY 83 ? A GLY 21 +22 1 Y 1 A SER 84 ? A SER 22 +23 1 Y 1 A HIS 85 ? A HIS 23 +24 1 Y 1 A SER 86 ? A SER 24 +25 1 Y 1 A GLY 87 ? A GLY 25 +26 1 Y 1 A SER 88 ? A SER 26 +27 1 Y 1 A TYR 140 ? A TYR 78 +28 1 Y 1 A ARG 141 ? A ARG 79 +29 1 Y 1 A GLU 142 ? A GLU 80 +30 1 Y 1 A GLN 143 ? A GLN 81 +31 1 Y 1 A MET 144 ? A MET 82 +32 1 Y 1 A ASN 145 ? A ASN 83 +33 1 Y 1 A LEU 146 ? A LEU 84 +34 1 Y 1 A THR 147 ? A THR 85 +35 1 Y 1 A SER 148 ? A SER 86 +36 1 Y 1 A LEU 149 ? A LEU 87 +37 1 Y 1 A VAL 527 ? A VAL 465 +38 1 Y 1 A GLU 528 ? A GLU 466 +39 1 Y 1 A GLN 529 ? A GLN 467 +40 1 Y 1 C MET 1 ? B MET 1 +41 1 Y 1 C ILE 2 ? B ILE 2 +42 1 Y 1 C LEU 3 ? B LEU 3 +43 1 Y 1 C PHE 4 ? B PHE 4 +44 1 Y 1 C ARG 5 ? B ARG 5 +45 1 Y 1 C LYS 6 ? B LYS 6 +46 1 Y 1 C PHE 7 ? B PHE 7 +47 1 Y 1 C ARG 8 ? B ARG 8 +48 1 Y 1 C VAL 9 ? B VAL 9 +49 1 Y 1 C LEU 10 ? B LEU 10 +50 1 Y 1 C ILE 11 ? B ILE 11 +51 1 Y 1 C LEU 12 ? B LEU 12 +52 1 Y 1 C THR 13 ? B THR 13 +53 1 Y 1 C VAL 14 ? B VAL 14 +54 1 Y 1 C PHE 15 ? B PHE 15 +55 1 Y 1 C LEU 16 ? B LEU 16 +56 1 Y 1 C ILE 17 ? B ILE 17 +57 1 Y 1 C ALA 18 ? B ALA 18 +58 1 Y 1 C CYS 19 ? B CYS 19 +59 1 Y 1 C THR 20 ? B THR 20 +60 1 Y 1 C MET 21 ? B MET 21 +61 1 Y 1 C HIS 22 ? B HIS 22 +62 1 Y 1 C ILE 23 ? B ILE 23 +63 1 Y 1 C MET 24 ? B MET 24 +64 1 Y 1 C ILE 25 ? B ILE 25 +65 1 Y 1 C ASP 26 ? B ASP 26 +66 1 Y 1 C LEU 27 ? B LEU 27 +67 1 Y 1 C LEU 28 ? B LEU 28 +68 1 Y 1 C PRO 29 ? B PRO 29 +69 1 Y 1 C LYS 30 ? B LYS 30 +70 1 Y 1 C LEU 31 ? B LEU 31 +71 1 Y 1 C GLU 32 ? B GLU 32 +72 1 Y 1 C LYS 33 ? B LYS 33 +73 1 Y 1 C ARG 34 ? B ARG 34 +74 1 Y 1 C ALA 35 ? B ALA 35 +75 1 Y 1 C ALA 36 ? B ALA 36 +76 1 Y 1 C GLY 37 ? B GLY 37 +77 1 Y 1 C SER 38 ? B SER 38 +78 1 Y 1 C SER 39 ? B SER 39 +79 1 Y 1 C SER 40 ? B SER 40 +80 1 Y 1 C SER 41 ? B SER 41 +81 1 Y 1 C ALA 42 ? B ALA 42 +82 1 Y 1 C GLY 43 ? B GLY 43 +83 1 Y 1 C GLY 44 ? B GLY 44 +84 1 Y 1 C GLY 45 ? B GLY 45 +85 1 Y 1 C SER 46 ? B SER 46 +86 1 Y 1 C GLY 47 ? B GLY 47 +87 1 Y 1 C CYS 48 ? B CYS 48 +88 1 Y 1 C SER 49 ? B SER 49 +89 1 Y 1 C CYS 50 ? B CYS 50 +90 1 Y 1 C ALA 51 ? B ALA 51 +91 1 Y 1 C HIS 52 ? B HIS 52 +92 1 Y 1 C THR 53 ? B THR 53 +93 1 Y 1 C PRO 54 ? B PRO 54 +94 1 Y 1 C GLY 55 ? B GLY 55 +95 1 Y 1 C GLU 56 ? B GLU 56 +96 1 Y 1 C GLU 57 ? B GLU 57 +97 1 Y 1 C PRO 58 ? B PRO 58 +98 1 Y 1 C ARG 59 ? B ARG 59 +99 1 Y 1 C SER 60 ? B SER 60 +100 1 Y 1 C TRP 61 ? B TRP 61 +101 1 Y 1 C GLY 62 ? B GLY 62 +102 1 Y 1 C LYS 63 ? B LYS 63 +103 1 Y 1 C GLN 64 ? B GLN 64 +104 1 Y 1 C ARG 65 ? B ARG 65 +105 1 Y 1 C ALA 66 ? B ALA 66 +106 1 Y 1 C ARG 67 ? B ARG 67 +107 1 Y 1 C ALA 68 ? B ALA 68 +108 1 Y 1 C ALA 69 ? B ALA 69 +109 1 Y 1 C ASP 70 ? B ASP 70 +110 1 Y 1 C PRO 71 ? B PRO 71 +111 1 Y 1 C GLY 72 ? B GLY 72 +112 1 Y 1 C TRP 73 ? B TRP 73 +113 1 Y 1 C PRO 74 ? B PRO 74 +114 1 Y 1 C ASN 75 ? B ASN 75 +115 1 Y 1 C LYS 76 ? B LYS 76 +116 1 Y 1 C HIS 77 ? B HIS 77 +117 1 Y 1 C SER 78 ? B SER 78 +118 1 Y 1 C LEU 79 ? B LEU 79 +119 1 Y 1 C ARG 80 ? B ARG 80 +120 1 Y 1 C LEU 81 ? B LEU 81 +121 1 Y 1 C LEU 82 ? B LEU 82 +122 1 Y 1 C GLN 83 ? B GLN 83 +123 1 Y 1 C ASP 84 ? B ASP 84 +124 1 Y 1 C PHE 85 ? B PHE 85 +125 1 Y 1 C SER 86 ? B SER 86 +126 1 Y 1 C ASN 87 ? B ASN 87 +127 1 Y 1 C GLU 88 ? B GLU 88 +128 1 Y 1 C PRO 89 ? B PRO 89 +129 1 Y 1 C ASN 90 ? B ASN 90 +130 1 Y 1 C SER 91 ? B SER 91 +131 1 Y 1 C ASN 92 ? B ASN 92 +132 1 Y 1 C LEU 93 ? B LEU 93 +133 1 Y 1 C THR 94 ? B THR 94 +134 1 Y 1 C SER 95 ? B SER 95 +135 1 Y 1 C GLN 96 ? B GLN 96 +136 1 Y 1 C SER 97 ? B SER 97 +137 1 Y 1 C ARG 98 ? B ARG 98 +138 1 Y 1 C GLU 99 ? B GLU 99 +139 1 Y 1 C LYS 100 ? B LYS 100 +140 1 Y 1 C VAL 101 ? B VAL 101 +141 1 Y 1 C THR 102 ? B THR 102 +142 1 Y 1 C GLU 103 ? B GLU 103 +143 1 Y 1 C ARG 104 ? B ARG 104 +144 1 Y 1 C ALA 105 ? B ALA 105 +145 1 Y 1 C GLY 106 ? B GLY 106 +146 1 Y 1 C SER 107 ? B SER 107 +147 1 Y 1 C GLU 108 ? B GLU 108 +148 1 Y 1 C LYS 109 ? B LYS 109 +149 1 Y 1 C GLN 110 ? B GLN 110 +150 1 Y 1 C GLY 111 ? B GLY 111 +151 1 Y 1 C SER 112 ? B SER 112 +152 1 Y 1 C GLY 113 ? B GLY 113 +153 1 Y 1 C LYS 114 ? B LYS 114 +154 1 Y 1 C ARG 115 ? B ARG 115 +155 1 Y 1 C GLY 116 ? B GLY 116 +156 1 Y 1 C LEU 117 ? B LEU 117 +157 1 Y 1 C MET 118 ? B MET 118 +158 1 Y 1 C ARG 119 ? B ARG 119 +159 1 Y 1 C GLU 120 ? B GLU 120 +160 1 Y 1 C ALA 121 ? B ALA 121 +161 1 Y 1 C ASP 122 ? B ASP 122 +162 1 Y 1 C SER 123 ? B SER 123 +163 1 Y 1 C ARG 124 ? B ARG 124 +164 1 Y 1 C GLN 125 ? B GLN 125 +165 1 Y 1 C ARG 126 ? B ARG 126 +166 1 Y 1 C ARG 127 ? B ARG 127 +167 1 Y 1 C THR 128 ? B THR 128 +168 1 Y 1 C ASP 129 ? B ASP 129 +169 1 Y 1 C VAL 130 ? B VAL 130 +170 1 Y 1 C ARG 131 ? B ARG 131 +171 1 Y 1 C VAL 132 ? B VAL 132 +172 1 Y 1 C SER 133 ? B SER 133 +173 1 Y 1 C GLY 173 ? B GLY 173 +174 1 Y 1 C GLN 174 ? B GLN 174 +175 1 Y 1 C GLN 175 ? B GLN 175 +176 1 Y 1 C GLU 176 ? B GLU 176 +177 1 Y 1 C TRP 177 ? B TRP 177 +178 1 Y 1 C HIS 178 ? B HIS 178 +179 1 Y 1 C ASN 179 ? B ASN 179 +180 1 Y 1 C GLU 180 ? B GLU 180 +181 1 Y 1 C GLY 181 ? B GLY 181 +182 1 Y 1 C ASN 182 ? B ASN 182 +183 1 Y 1 C VAL 183 ? B VAL 183 +184 1 Y 1 C GLU 184 ? B GLU 184 +185 1 Y 1 C GLU 185 ? B GLU 185 +186 1 Y 1 C GLU 186 ? B GLU 186 +187 1 Y 1 C GLU 187 ? B GLU 187 +188 1 Y 1 C PHE 188 ? B PHE 188 +189 1 Y 1 C SER 189 ? B SER 189 +190 1 Y 1 C PRO 190 ? B PRO 190 +191 1 Y 1 C PRO 191 ? B PRO 191 +192 1 Y 1 C GLY 192 ? B GLY 192 +193 1 Y 1 C GLU 193 ? B GLU 193 +194 1 Y 1 C ALA 194 ? B ALA 194 +195 1 Y 1 C ASN 195 ? B ASN 195 +196 1 Y 1 C GLY 552 ? B GLY 552 +197 1 Y 1 C GLN 553 ? B GLN 553 +198 1 Y 1 C PRO 554 ? B PRO 554 +199 1 Y 1 C SER 555 ? B SER 555 +200 1 Y 1 C VAL 556 ? B VAL 556 +201 1 Y 1 C HIS 557 ? B HIS 557 +202 1 Y 1 C GLY 558 ? B GLY 558 +203 1 Y 1 C GLY 559 ? B GLY 559 +204 1 Y 1 C ARG 560 ? B ARG 560 +205 1 Y 1 B ASP 63 ? C ASP 1 +206 1 Y 1 B PRO 64 ? C PRO 2 +207 1 Y 1 B GLY 65 ? C GLY 3 +208 1 Y 1 B THR 66 ? C THR 4 +209 1 Y 1 B ILE 67 ? C ILE 5 +210 1 Y 1 B VAL 68 ? C VAL 6 +211 1 Y 1 B HIS 69 ? C HIS 7 +212 1 Y 1 B ASN 70 ? C ASN 8 +213 1 Y 1 B PHE 71 ? C PHE 9 +214 1 Y 1 B SER 72 ? C SER 10 +215 1 Y 1 B ARG 73 ? C ARG 11 +216 1 Y 1 B THR 74 ? C THR 12 +217 1 Y 1 B GLU 75 ? C GLU 13 +218 1 Y 1 B PRO 76 ? C PRO 14 +219 1 Y 1 B ARG 77 ? C ARG 15 +220 1 Y 1 B THR 78 ? C THR 16 +221 1 Y 1 B GLU 79 ? C GLU 17 +222 1 Y 1 B PRO 80 ? C PRO 18 +223 1 Y 1 B ALA 81 ? C ALA 19 +224 1 Y 1 B GLY 82 ? C GLY 20 +225 1 Y 1 B GLY 83 ? C GLY 21 +226 1 Y 1 B SER 84 ? C SER 22 +227 1 Y 1 B HIS 85 ? C HIS 23 +228 1 Y 1 B SER 86 ? C SER 24 +229 1 Y 1 B GLY 87 ? C GLY 25 +230 1 Y 1 B SER 88 ? C SER 26 +231 1 Y 1 B ARG 141 ? C ARG 79 +232 1 Y 1 B GLU 142 ? C GLU 80 +233 1 Y 1 B GLN 143 ? C GLN 81 +234 1 Y 1 B MET 144 ? C MET 82 +235 1 Y 1 B ASN 145 ? C ASN 83 +236 1 Y 1 B LEU 146 ? C LEU 84 +237 1 Y 1 B THR 147 ? C THR 85 +238 1 Y 1 B SER 148 ? C SER 86 +239 1 Y 1 B LEU 149 ? C LEU 87 +240 1 Y 1 B ASP 150 ? C ASP 88 +241 1 Y 1 B VAL 527 ? C VAL 465 +242 1 Y 1 B GLU 528 ? C GLU 466 +243 1 Y 1 B GLN 529 ? C GLN 467 +244 1 Y 1 D MET 1 ? D MET 1 +245 1 Y 1 D ILE 2 ? D ILE 2 +246 1 Y 1 D LEU 3 ? D LEU 3 +247 1 Y 1 D PHE 4 ? D PHE 4 +248 1 Y 1 D ARG 5 ? D ARG 5 +249 1 Y 1 D LYS 6 ? D LYS 6 +250 1 Y 1 D PHE 7 ? D PHE 7 +251 1 Y 1 D ARG 8 ? D ARG 8 +252 1 Y 1 D VAL 9 ? D VAL 9 +253 1 Y 1 D LEU 10 ? D LEU 10 +254 1 Y 1 D ILE 11 ? D ILE 11 +255 1 Y 1 D LEU 12 ? D LEU 12 +256 1 Y 1 D THR 13 ? D THR 13 +257 1 Y 1 D VAL 14 ? D VAL 14 +258 1 Y 1 D PHE 15 ? D PHE 15 +259 1 Y 1 D LEU 16 ? D LEU 16 +260 1 Y 1 D ILE 17 ? D ILE 17 +261 1 Y 1 D ALA 18 ? D ALA 18 +262 1 Y 1 D CYS 19 ? D CYS 19 +263 1 Y 1 D THR 20 ? D THR 20 +264 1 Y 1 D MET 21 ? D MET 21 +265 1 Y 1 D HIS 22 ? D HIS 22 +266 1 Y 1 D ILE 23 ? D ILE 23 +267 1 Y 1 D MET 24 ? D MET 24 +268 1 Y 1 D ILE 25 ? D ILE 25 +269 1 Y 1 D ASP 26 ? D ASP 26 +270 1 Y 1 D LEU 27 ? D LEU 27 +271 1 Y 1 D LEU 28 ? D LEU 28 +272 1 Y 1 D PRO 29 ? D PRO 29 +273 1 Y 1 D LYS 30 ? D LYS 30 +274 1 Y 1 D LEU 31 ? D LEU 31 +275 1 Y 1 D GLU 32 ? D GLU 32 +276 1 Y 1 D LYS 33 ? D LYS 33 +277 1 Y 1 D ARG 34 ? D ARG 34 +278 1 Y 1 D ALA 35 ? D ALA 35 +279 1 Y 1 D ALA 36 ? D ALA 36 +280 1 Y 1 D GLY 37 ? D GLY 37 +281 1 Y 1 D SER 38 ? D SER 38 +282 1 Y 1 D SER 39 ? D SER 39 +283 1 Y 1 D SER 40 ? D SER 40 +284 1 Y 1 D SER 41 ? D SER 41 +285 1 Y 1 D ALA 42 ? D ALA 42 +286 1 Y 1 D GLY 43 ? D GLY 43 +287 1 Y 1 D GLY 44 ? D GLY 44 +288 1 Y 1 D GLY 45 ? D GLY 45 +289 1 Y 1 D SER 46 ? D SER 46 +290 1 Y 1 D GLY 47 ? D GLY 47 +291 1 Y 1 D CYS 48 ? D CYS 48 +292 1 Y 1 D SER 49 ? D SER 49 +293 1 Y 1 D CYS 50 ? D CYS 50 +294 1 Y 1 D ALA 51 ? D ALA 51 +295 1 Y 1 D HIS 52 ? D HIS 52 +296 1 Y 1 D THR 53 ? D THR 53 +297 1 Y 1 D PRO 54 ? D PRO 54 +298 1 Y 1 D GLY 55 ? D GLY 55 +299 1 Y 1 D GLU 56 ? D GLU 56 +300 1 Y 1 D GLU 57 ? D GLU 57 +301 1 Y 1 D PRO 58 ? D PRO 58 +302 1 Y 1 D ARG 59 ? D ARG 59 +303 1 Y 1 D SER 60 ? D SER 60 +304 1 Y 1 D TRP 61 ? D TRP 61 +305 1 Y 1 D GLY 62 ? D GLY 62 +306 1 Y 1 D LYS 63 ? D LYS 63 +307 1 Y 1 D GLN 64 ? D GLN 64 +308 1 Y 1 D ARG 65 ? D ARG 65 +309 1 Y 1 D ALA 66 ? D ALA 66 +310 1 Y 1 D ARG 67 ? D ARG 67 +311 1 Y 1 D ALA 68 ? D ALA 68 +312 1 Y 1 D ALA 69 ? D ALA 69 +313 1 Y 1 D ASP 70 ? D ASP 70 +314 1 Y 1 D PRO 71 ? D PRO 71 +315 1 Y 1 D GLY 72 ? D GLY 72 +316 1 Y 1 D TRP 73 ? D TRP 73 +317 1 Y 1 D PRO 74 ? D PRO 74 +318 1 Y 1 D ASN 75 ? D ASN 75 +319 1 Y 1 D LYS 76 ? D LYS 76 +320 1 Y 1 D HIS 77 ? D HIS 77 +321 1 Y 1 D SER 78 ? D SER 78 +322 1 Y 1 D LEU 79 ? D LEU 79 +323 1 Y 1 D ARG 80 ? D ARG 80 +324 1 Y 1 D LEU 81 ? D LEU 81 +325 1 Y 1 D LEU 82 ? D LEU 82 +326 1 Y 1 D GLN 83 ? D GLN 83 +327 1 Y 1 D ASP 84 ? D ASP 84 +328 1 Y 1 D PHE 85 ? D PHE 85 +329 1 Y 1 D SER 86 ? D SER 86 +330 1 Y 1 D ASN 87 ? D ASN 87 +331 1 Y 1 D GLU 88 ? D GLU 88 +332 1 Y 1 D PRO 89 ? D PRO 89 +333 1 Y 1 D ASN 90 ? D ASN 90 +334 1 Y 1 D SER 91 ? D SER 91 +335 1 Y 1 D ASN 92 ? D ASN 92 +336 1 Y 1 D LEU 93 ? D LEU 93 +337 1 Y 1 D THR 94 ? D THR 94 +338 1 Y 1 D SER 95 ? D SER 95 +339 1 Y 1 D GLN 96 ? D GLN 96 +340 1 Y 1 D SER 97 ? D SER 97 +341 1 Y 1 D ARG 98 ? D ARG 98 +342 1 Y 1 D GLU 99 ? D GLU 99 +343 1 Y 1 D LYS 100 ? D LYS 100 +344 1 Y 1 D VAL 101 ? D VAL 101 +345 1 Y 1 D THR 102 ? D THR 102 +346 1 Y 1 D GLU 103 ? D GLU 103 +347 1 Y 1 D ARG 104 ? D ARG 104 +348 1 Y 1 D ALA 105 ? D ALA 105 +349 1 Y 1 D GLY 106 ? D GLY 106 +350 1 Y 1 D SER 107 ? D SER 107 +351 1 Y 1 D GLU 108 ? D GLU 108 +352 1 Y 1 D LYS 109 ? D LYS 109 +353 1 Y 1 D GLN 110 ? D GLN 110 +354 1 Y 1 D GLY 111 ? D GLY 111 +355 1 Y 1 D SER 112 ? D SER 112 +356 1 Y 1 D GLY 113 ? D GLY 113 +357 1 Y 1 D LYS 114 ? D LYS 114 +358 1 Y 1 D ARG 115 ? D ARG 115 +359 1 Y 1 D GLY 116 ? D GLY 116 +360 1 Y 1 D LEU 117 ? D LEU 117 +361 1 Y 1 D MET 118 ? D MET 118 +362 1 Y 1 D ARG 119 ? D ARG 119 +363 1 Y 1 D GLU 120 ? D GLU 120 +364 1 Y 1 D ALA 121 ? D ALA 121 +365 1 Y 1 D ASP 122 ? D ASP 122 +366 1 Y 1 D SER 123 ? D SER 123 +367 1 Y 1 D ARG 124 ? D ARG 124 +368 1 Y 1 D GLN 125 ? D GLN 125 +369 1 Y 1 D ARG 126 ? D ARG 126 +370 1 Y 1 D ARG 127 ? D ARG 127 +371 1 Y 1 D THR 128 ? D THR 128 +372 1 Y 1 D ASP 129 ? D ASP 129 +373 1 Y 1 D VAL 130 ? D VAL 130 +374 1 Y 1 D ARG 131 ? D ARG 131 +375 1 Y 1 D VAL 132 ? D VAL 132 +376 1 Y 1 D SER 133 ? D SER 133 +377 1 Y 1 D ALA 172 ? D ALA 172 +378 1 Y 1 D GLY 173 ? D GLY 173 +379 1 Y 1 D GLN 174 ? D GLN 174 +380 1 Y 1 D GLN 175 ? D GLN 175 +381 1 Y 1 D GLU 176 ? D GLU 176 +382 1 Y 1 D TRP 177 ? D TRP 177 +383 1 Y 1 D HIS 178 ? D HIS 178 +384 1 Y 1 D ASN 179 ? D ASN 179 +385 1 Y 1 D GLU 180 ? D GLU 180 +386 1 Y 1 D GLY 181 ? D GLY 181 +387 1 Y 1 D ASN 182 ? D ASN 182 +388 1 Y 1 D VAL 183 ? D VAL 183 +389 1 Y 1 D GLU 184 ? D GLU 184 +390 1 Y 1 D GLU 185 ? D GLU 185 +391 1 Y 1 D GLU 186 ? D GLU 186 +392 1 Y 1 D GLU 187 ? D GLU 187 +393 1 Y 1 D PHE 188 ? D PHE 188 +394 1 Y 1 D SER 189 ? D SER 189 +395 1 Y 1 D PRO 190 ? D PRO 190 +396 1 Y 1 D PRO 191 ? D PRO 191 +397 1 Y 1 D GLY 192 ? D GLY 192 +398 1 Y 1 D GLU 193 ? D GLU 193 +399 1 Y 1 D ALA 194 ? D ALA 194 +400 1 Y 1 D ASN 195 ? D ASN 195 +401 1 Y 1 D SER 196 ? D SER 196 +402 1 Y 1 D GLN 553 ? D GLN 553 +403 1 Y 1 D PRO 554 ? D PRO 554 +404 1 Y 1 D SER 555 ? D SER 555 +405 1 Y 1 D VAL 556 ? D VAL 556 +406 1 Y 1 D HIS 557 ? D HIS 557 +407 1 Y 1 D GLY 558 ? D GLY 558 +408 1 Y 1 D GLY 559 ? D GLY 559 +409 1 Y 1 D ARG 560 ? D ARG 560 +# +_pdbx_entity_nonpoly.entity_id 3 +_pdbx_entity_nonpoly.name "ADENOSINE-5'-TRIPHOSPHATE" +_pdbx_entity_nonpoly.comp_id ATP +# +_pdbx_struct_assembly_auth_evidence.id 1 +_pdbx_struct_assembly_auth_evidence.assembly_id 1 +_pdbx_struct_assembly_auth_evidence.experimental_support 'gel filtration' +_pdbx_struct_assembly_auth_evidence.details ? +# diff --git a/esm/source/examples/inverse_folding/data/5YH2.pdb b/esm/source/examples/inverse_folding/data/5YH2.pdb new file mode 100644 index 0000000000000000000000000000000000000000..2b51e05e36457dc64987a994a8f65696ebc13f43 --- /dev/null +++ b/esm/source/examples/inverse_folding/data/5YH2.pdb @@ -0,0 +1,14725 @@ +HEADER TRANSFERASE 27-SEP-17 5YH2 +TITLE THE STRUCTURE OF DRFAM20C1 AND HFAM20A COMPLEX +COMPND MOL_ID: 1; +COMPND 2 MOLECULE: PSEUDOKINASE FAM20A; +COMPND 3 CHAIN: A, B; +COMPND 4 FRAGMENT: UNP RESIDUES 63-529; +COMPND 5 ENGINEERED: YES; +COMPND 6 MOL_ID: 2; +COMPND 7 MOLECULE: FAMILY WITH SEQUENCE SIMILARITY 20, MEMBER CA; +COMPND 8 CHAIN: C, D; +COMPND 9 SYNONYM: DRFAM20C1; +COMPND 10 ENGINEERED: YES; +COMPND 11 MUTATION: YES +SOURCE MOL_ID: 1; +SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; +SOURCE 3 ORGANISM_COMMON: HUMAN; +SOURCE 4 ORGANISM_TAXID: 9606; +SOURCE 5 GENE: FAM20A, UNQ9388/PRO34279; +SOURCE 6 EXPRESSION_SYSTEM: TRICHOPLUSIA NI; +SOURCE 7 EXPRESSION_SYSTEM_TAXID: 7111; +SOURCE 8 MOL_ID: 2; +SOURCE 9 ORGANISM_SCIENTIFIC: DANIO RERIO; +SOURCE 10 ORGANISM_COMMON: ZEBRAFISH; +SOURCE 11 ORGANISM_TAXID: 7955; +SOURCE 12 GENE: FAM20CA; +SOURCE 13 EXPRESSION_SYSTEM: TRICHOPLUSIA NI; +SOURCE 14 EXPRESSION_SYSTEM_TAXID: 7111 +KEYWDS COMPLEX, KINASE, TRANSFERASE +EXPDTA X-RAY DIFFRACTION +AUTHOR H.ZHANG,J.XIAO +REVDAT 2 25-APR-18 5YH2 1 COMPND SOURCE DBREF SEQADV +REVDAT 1 11-APR-18 5YH2 0 +JRNL AUTH H.ZHANG,Q.ZHU,J.CUI,Y.WANG,M.J.CHEN,X.GUO,V.S.TAGLIABRACCI, +JRNL AUTH 2 J.E.DIXON,J.XIAO +JRNL TITL STRUCTURE AND EVOLUTION OF THE FAM20 KINASES +JRNL REF NAT COMMUN V. 9 1218 2018 +JRNL REFN ESSN 2041-1723 +JRNL PMID 29572475 +JRNL DOI 10.1038/S41467-018-03615-Z +REMARK 2 +REMARK 2 RESOLUTION. 3.55 ANGSTROMS. +REMARK 3 +REMARK 3 REFINEMENT. +REMARK 3 PROGRAM : PHENIX 1.11.1_2575 +REMARK 3 AUTHORS : PAUL ADAMS,PAVEL AFONINE,VINCENT CHEN,IAN +REMARK 3 : DAVIS,KRESHNA GOPAL,RALF GROSSE-KUNSTLEVE, +REMARK 3 : LI-WEI HUNG,ROBERT IMMORMINO,TOM IOERGER, +REMARK 3 : AIRLIE MCCOY,ERIK MCKEE,NIGEL MORIARTY, +REMARK 3 : REETAL PAI,RANDY READ,JANE RICHARDSON, +REMARK 3 : DAVID RICHARDSON,TOD ROMO,JIM SACCHETTINI, +REMARK 3 : NICHOLAS SAUTER,JACOB SMITH,LAURENT +REMARK 3 : STORONI,TOM TERWILLIGER,PETER ZWART +REMARK 3 +REMARK 3 REFINEMENT TARGET : NULL +REMARK 3 +REMARK 3 DATA USED IN REFINEMENT. +REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 3.55 +REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 48.94 +REMARK 3 MIN(FOBS/SIGMA_FOBS) : 1.340 +REMARK 3 COMPLETENESS FOR RANGE (%) : 87.7 +REMARK 3 NUMBER OF REFLECTIONS : 31136 +REMARK 3 +REMARK 3 FIT TO DATA USED IN REFINEMENT. +REMARK 3 R VALUE (WORKING + TEST SET) : 0.248 +REMARK 3 R VALUE (WORKING SET) : 0.245 +REMARK 3 FREE R VALUE : 0.298 +REMARK 3 FREE R VALUE TEST SET SIZE (%) : 5.000 +REMARK 3 FREE R VALUE TEST SET COUNT : 1556 +REMARK 3 +REMARK 3 FIT TO DATA USED IN REFINEMENT (IN BINS). +REMARK 3 BIN RESOLUTION RANGE COMPL. NWORK NFREE RWORK RFREE +REMARK 3 1 48.9472 - 7.8860 0.98 3270 171 0.2169 0.2582 +REMARK 3 2 7.8860 - 6.2635 1.00 3161 166 0.2337 0.2823 +REMARK 3 3 6.2635 - 5.4729 1.00 3076 163 0.2375 0.2841 +REMARK 3 4 5.4729 - 4.9731 1.00 3062 161 0.2260 0.2819 +REMARK 3 5 4.9731 - 4.6169 1.00 3051 160 0.2193 0.2652 +REMARK 3 6 4.6169 - 4.3449 1.00 3037 160 0.2402 0.2814 +REMARK 3 7 4.3449 - 4.1274 1.00 3000 158 0.2688 0.3580 +REMARK 3 8 4.1274 - 3.9478 0.99 2973 157 0.2931 0.3451 +REMARK 3 9 3.9478 - 3.7959 0.77 2288 120 0.2929 0.3518 +REMARK 3 10 3.7959 - 3.6650 0.50 1493 78 0.2939 0.3970 +REMARK 3 11 3.6650 - 3.5504 0.39 1169 62 0.2907 0.3218 +REMARK 3 +REMARK 3 BULK SOLVENT MODELLING. +REMARK 3 METHOD USED : NULL +REMARK 3 SOLVENT RADIUS : 1.11 +REMARK 3 SHRINKAGE RADIUS : 0.90 +REMARK 3 K_SOL : NULL +REMARK 3 B_SOL : NULL +REMARK 3 +REMARK 3 ERROR ESTIMATES. +REMARK 3 COORDINATE ERROR (MAXIMUM-LIKELIHOOD BASED) : 0.500 +REMARK 3 PHASE ERROR (DEGREES, MAXIMUM-LIKELIHOOD BASED) : 28.880 +REMARK 3 +REMARK 3 B VALUES. +REMARK 3 FROM WILSON PLOT (A**2) : NULL +REMARK 3 MEAN B VALUE (OVERALL, A**2) : NULL +REMARK 3 OVERALL ANISOTROPIC B VALUE. +REMARK 3 B11 (A**2) : NULL +REMARK 3 B22 (A**2) : NULL +REMARK 3 B33 (A**2) : NULL +REMARK 3 B12 (A**2) : NULL +REMARK 3 B13 (A**2) : NULL +REMARK 3 B23 (A**2) : NULL +REMARK 3 +REMARK 3 TWINNING INFORMATION. +REMARK 3 FRACTION: NULL +REMARK 3 OPERATOR: NULL +REMARK 3 +REMARK 3 DEVIATIONS FROM IDEAL VALUES. +REMARK 3 RMSD COUNT +REMARK 3 BOND : 0.005 13846 +REMARK 3 ANGLE : 0.739 18758 +REMARK 3 CHIRALITY : 0.044 2028 +REMARK 3 PLANARITY : 0.006 2410 +REMARK 3 DIHEDRAL : 15.217 8431 +REMARK 3 +REMARK 3 TLS DETAILS +REMARK 3 NUMBER OF TLS GROUPS : NULL +REMARK 3 +REMARK 3 NCS DETAILS +REMARK 3 NUMBER OF NCS GROUPS : NULL +REMARK 3 +REMARK 3 OTHER REFINEMENT REMARKS: NULL +REMARK 4 +REMARK 4 5YH2 COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 +REMARK 100 +REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBJ ON 28-SEP-17. +REMARK 100 THE DEPOSITION ID IS D_1300005266. +REMARK 200 +REMARK 200 EXPERIMENTAL DETAILS +REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION +REMARK 200 DATE OF DATA COLLECTION : 02-OCT-16 +REMARK 200 TEMPERATURE (KELVIN) : 100 +REMARK 200 PH : 5.0 +REMARK 200 NUMBER OF CRYSTALS USED : 1 +REMARK 200 +REMARK 200 SYNCHROTRON (Y/N) : Y +REMARK 200 RADIATION SOURCE : SSRF +REMARK 200 BEAMLINE : BL18U1 +REMARK 200 X-RAY GENERATOR MODEL : NULL +REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M +REMARK 200 WAVELENGTH OR RANGE (A) : 0.977 +REMARK 200 MONOCHROMATOR : NULL +REMARK 200 OPTICS : NULL +REMARK 200 +REMARK 200 DETECTOR TYPE : PIXEL +REMARK 200 DETECTOR MANUFACTURER : DECTRIS PILATUS3 6M +REMARK 200 INTENSITY-INTEGRATION SOFTWARE : NULL +REMARK 200 DATA SCALING SOFTWARE : HKL-2000 +REMARK 200 +REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 35615 +REMARK 200 RESOLUTION RANGE HIGH (A) : 3.550 +REMARK 200 RESOLUTION RANGE LOW (A) : 50.000 +REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL +REMARK 200 +REMARK 200 OVERALL. +REMARK 200 COMPLETENESS FOR RANGE (%) : 100.0 +REMARK 200 DATA REDUNDANCY : 11.40 +REMARK 200 R MERGE (I) : NULL +REMARK 200 R SYM (I) : NULL +REMARK 200 FOR THE DATA SET : 11.0000 +REMARK 200 +REMARK 200 IN THE HIGHEST RESOLUTION SHELL. +REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : NULL +REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : NULL +REMARK 200 COMPLETENESS FOR SHELL (%) : NULL +REMARK 200 DATA REDUNDANCY IN SHELL : NULL +REMARK 200 R MERGE FOR SHELL (I) : NULL +REMARK 200 R SYM FOR SHELL (I) : NULL +REMARK 200 FOR SHELL : NULL +REMARK 200 +REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH +REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: NULL +REMARK 200 SOFTWARE USED: PHENIX +REMARK 200 STARTING MODEL: NULL +REMARK 200 +REMARK 200 REMARK: NULL +REMARK 280 +REMARK 280 CRYSTAL +REMARK 280 SOLVENT CONTENT, VS (%): 58.49 +REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.96 +REMARK 280 +REMARK 280 CRYSTALLIZATION CONDITIONS: 11% V/V 2-PROPANOL, 0.1 M SODIUM +REMARK 280 CITRATE TRIBASIC DIHYDRATE PH 5.0, 8% W/V POLYETHYLENE GLYCOL 10, +REMARK 280 000, VAPOR DIFFUSION, SITTING DROP, TEMPERATURE 290K +REMARK 290 +REMARK 290 CRYSTALLOGRAPHIC SYMMETRY +REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 41 21 2 +REMARK 290 +REMARK 290 SYMOP SYMMETRY +REMARK 290 NNNMMM OPERATOR +REMARK 290 1555 X,Y,Z +REMARK 290 2555 -X,-Y,Z+1/2 +REMARK 290 3555 -Y+1/2,X+1/2,Z+1/4 +REMARK 290 4555 Y+1/2,-X+1/2,Z+3/4 +REMARK 290 5555 -X+1/2,Y+1/2,-Z+1/4 +REMARK 290 6555 X+1/2,-Y+1/2,-Z+3/4 +REMARK 290 7555 Y,X,-Z +REMARK 290 8555 -Y,-X,-Z+1/2 +REMARK 290 +REMARK 290 WHERE NNN -> OPERATOR NUMBER +REMARK 290 MMM -> TRANSLATION VECTOR +REMARK 290 +REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS +REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM +REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY +REMARK 290 RELATED MOLECULES. +REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 +REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 +REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 +REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 +REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000 +REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 230.84900 +REMARK 290 SMTRY1 3 0.000000 -1.000000 0.000000 55.02950 +REMARK 290 SMTRY2 3 1.000000 0.000000 0.000000 55.02950 +REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 115.42450 +REMARK 290 SMTRY1 4 0.000000 1.000000 0.000000 55.02950 +REMARK 290 SMTRY2 4 -1.000000 0.000000 0.000000 55.02950 +REMARK 290 SMTRY3 4 0.000000 0.000000 1.000000 346.27350 +REMARK 290 SMTRY1 5 -1.000000 0.000000 0.000000 55.02950 +REMARK 290 SMTRY2 5 0.000000 1.000000 0.000000 55.02950 +REMARK 290 SMTRY3 5 0.000000 0.000000 -1.000000 115.42450 +REMARK 290 SMTRY1 6 1.000000 0.000000 0.000000 55.02950 +REMARK 290 SMTRY2 6 0.000000 -1.000000 0.000000 55.02950 +REMARK 290 SMTRY3 6 0.000000 0.000000 -1.000000 346.27350 +REMARK 290 SMTRY1 7 0.000000 1.000000 0.000000 0.00000 +REMARK 290 SMTRY2 7 1.000000 0.000000 0.000000 0.00000 +REMARK 290 SMTRY3 7 0.000000 0.000000 -1.000000 0.00000 +REMARK 290 SMTRY1 8 0.000000 -1.000000 0.000000 0.00000 +REMARK 290 SMTRY2 8 -1.000000 0.000000 0.000000 0.00000 +REMARK 290 SMTRY3 8 0.000000 0.000000 -1.000000 230.84900 +REMARK 290 +REMARK 290 REMARK: NULL +REMARK 300 +REMARK 300 BIOMOLECULE: 1 +REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM +REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN +REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON +REMARK 300 BURIED SURFACE AREA. +REMARK 350 +REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN +REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE +REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS +REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND +REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. +REMARK 350 +REMARK 350 BIOMOLECULE: 1 +REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC +REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TETRAMERIC +REMARK 350 SOFTWARE USED: PISA +REMARK 350 TOTAL BURIED SURFACE AREA: 9320 ANGSTROM**2 +REMARK 350 SURFACE AREA OF THE COMPLEX: 69550 ANGSTROM**2 +REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -36.0 KCAL/MOL +REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, C, B, D +REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 +REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 +REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 +REMARK 465 +REMARK 465 MISSING RESIDUES +REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE +REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN +REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) +REMARK 465 +REMARK 465 M RES C SSSEQI +REMARK 465 ASP A 63 +REMARK 465 PRO A 64 +REMARK 465 GLY A 65 +REMARK 465 THR A 66 +REMARK 465 ILE A 67 +REMARK 465 VAL A 68 +REMARK 465 HIS A 69 +REMARK 465 ASN A 70 +REMARK 465 PHE A 71 +REMARK 465 SER A 72 +REMARK 465 ARG A 73 +REMARK 465 THR A 74 +REMARK 465 GLU A 75 +REMARK 465 PRO A 76 +REMARK 465 ARG A 77 +REMARK 465 THR A 78 +REMARK 465 GLU A 79 +REMARK 465 PRO A 80 +REMARK 465 ALA A 81 +REMARK 465 GLY A 82 +REMARK 465 GLY A 83 +REMARK 465 SER A 84 +REMARK 465 HIS A 85 +REMARK 465 SER A 86 +REMARK 465 GLY A 87 +REMARK 465 SER A 88 +REMARK 465 TYR A 140 +REMARK 465 ARG A 141 +REMARK 465 GLU A 142 +REMARK 465 GLN A 143 +REMARK 465 MET A 144 +REMARK 465 ASN A 145 +REMARK 465 LEU A 146 +REMARK 465 THR A 147 +REMARK 465 SER A 148 +REMARK 465 LEU A 149 +REMARK 465 VAL A 527 +REMARK 465 GLU A 528 +REMARK 465 GLN A 529 +REMARK 465 MET C 1 +REMARK 465 ILE C 2 +REMARK 465 LEU C 3 +REMARK 465 PHE C 4 +REMARK 465 ARG C 5 +REMARK 465 LYS C 6 +REMARK 465 PHE C 7 +REMARK 465 ARG C 8 +REMARK 465 VAL C 9 +REMARK 465 LEU C 10 +REMARK 465 ILE C 11 +REMARK 465 LEU C 12 +REMARK 465 THR C 13 +REMARK 465 VAL C 14 +REMARK 465 PHE C 15 +REMARK 465 LEU C 16 +REMARK 465 ILE C 17 +REMARK 465 ALA C 18 +REMARK 465 CYS C 19 +REMARK 465 THR C 20 +REMARK 465 MET C 21 +REMARK 465 HIS C 22 +REMARK 465 ILE C 23 +REMARK 465 MET C 24 +REMARK 465 ILE C 25 +REMARK 465 ASP C 26 +REMARK 465 LEU C 27 +REMARK 465 LEU C 28 +REMARK 465 PRO C 29 +REMARK 465 LYS C 30 +REMARK 465 LEU C 31 +REMARK 465 GLU C 32 +REMARK 465 LYS C 33 +REMARK 465 ARG C 34 +REMARK 465 ALA C 35 +REMARK 465 ALA C 36 +REMARK 465 GLY C 37 +REMARK 465 SER C 38 +REMARK 465 SER C 39 +REMARK 465 SER C 40 +REMARK 465 SER C 41 +REMARK 465 ALA C 42 +REMARK 465 GLY C 43 +REMARK 465 GLY C 44 +REMARK 465 GLY C 45 +REMARK 465 SER C 46 +REMARK 465 GLY C 47 +REMARK 465 CYS C 48 +REMARK 465 SER C 49 +REMARK 465 CYS C 50 +REMARK 465 ALA C 51 +REMARK 465 HIS C 52 +REMARK 465 THR C 53 +REMARK 465 PRO C 54 +REMARK 465 GLY C 55 +REMARK 465 GLU C 56 +REMARK 465 GLU C 57 +REMARK 465 PRO C 58 +REMARK 465 ARG C 59 +REMARK 465 SER C 60 +REMARK 465 TRP C 61 +REMARK 465 GLY C 62 +REMARK 465 LYS C 63 +REMARK 465 GLN C 64 +REMARK 465 ARG C 65 +REMARK 465 ALA C 66 +REMARK 465 ARG C 67 +REMARK 465 ALA C 68 +REMARK 465 ALA C 69 +REMARK 465 ASP C 70 +REMARK 465 PRO C 71 +REMARK 465 GLY C 72 +REMARK 465 TRP C 73 +REMARK 465 PRO C 74 +REMARK 465 ASN C 75 +REMARK 465 LYS C 76 +REMARK 465 HIS C 77 +REMARK 465 SER C 78 +REMARK 465 LEU C 79 +REMARK 465 ARG C 80 +REMARK 465 LEU C 81 +REMARK 465 LEU C 82 +REMARK 465 GLN C 83 +REMARK 465 ASP C 84 +REMARK 465 PHE C 85 +REMARK 465 SER C 86 +REMARK 465 ASN C 87 +REMARK 465 GLU C 88 +REMARK 465 PRO C 89 +REMARK 465 ASN C 90 +REMARK 465 SER C 91 +REMARK 465 ASN C 92 +REMARK 465 LEU C 93 +REMARK 465 THR C 94 +REMARK 465 SER C 95 +REMARK 465 GLN C 96 +REMARK 465 SER C 97 +REMARK 465 ARG C 98 +REMARK 465 GLU C 99 +REMARK 465 LYS C 100 +REMARK 465 VAL C 101 +REMARK 465 THR C 102 +REMARK 465 GLU C 103 +REMARK 465 ARG C 104 +REMARK 465 ALA C 105 +REMARK 465 GLY C 106 +REMARK 465 SER C 107 +REMARK 465 GLU C 108 +REMARK 465 LYS C 109 +REMARK 465 GLN C 110 +REMARK 465 GLY C 111 +REMARK 465 SER C 112 +REMARK 465 GLY C 113 +REMARK 465 LYS C 114 +REMARK 465 ARG C 115 +REMARK 465 GLY C 116 +REMARK 465 LEU C 117 +REMARK 465 MET C 118 +REMARK 465 ARG C 119 +REMARK 465 GLU C 120 +REMARK 465 ALA C 121 +REMARK 465 ASP C 122 +REMARK 465 SER C 123 +REMARK 465 ARG C 124 +REMARK 465 GLN C 125 +REMARK 465 ARG C 126 +REMARK 465 ARG C 127 +REMARK 465 THR C 128 +REMARK 465 ASP C 129 +REMARK 465 VAL C 130 +REMARK 465 ARG C 131 +REMARK 465 VAL C 132 +REMARK 465 SER C 133 +REMARK 465 GLY C 173 +REMARK 465 GLN C 174 +REMARK 465 GLN C 175 +REMARK 465 GLU C 176 +REMARK 465 TRP C 177 +REMARK 465 HIS C 178 +REMARK 465 ASN C 179 +REMARK 465 GLU C 180 +REMARK 465 GLY C 181 +REMARK 465 ASN C 182 +REMARK 465 VAL C 183 +REMARK 465 GLU C 184 +REMARK 465 GLU C 185 +REMARK 465 GLU C 186 +REMARK 465 GLU C 187 +REMARK 465 PHE C 188 +REMARK 465 SER C 189 +REMARK 465 PRO C 190 +REMARK 465 PRO C 191 +REMARK 465 GLY C 192 +REMARK 465 GLU C 193 +REMARK 465 ALA C 194 +REMARK 465 ASN C 195 +REMARK 465 GLY C 552 +REMARK 465 GLN C 553 +REMARK 465 PRO C 554 +REMARK 465 SER C 555 +REMARK 465 VAL C 556 +REMARK 465 HIS C 557 +REMARK 465 GLY C 558 +REMARK 465 GLY C 559 +REMARK 465 ARG C 560 +REMARK 465 ASP B 63 +REMARK 465 PRO B 64 +REMARK 465 GLY B 65 +REMARK 465 THR B 66 +REMARK 465 ILE B 67 +REMARK 465 VAL B 68 +REMARK 465 HIS B 69 +REMARK 465 ASN B 70 +REMARK 465 PHE B 71 +REMARK 465 SER B 72 +REMARK 465 ARG B 73 +REMARK 465 THR B 74 +REMARK 465 GLU B 75 +REMARK 465 PRO B 76 +REMARK 465 ARG B 77 +REMARK 465 THR B 78 +REMARK 465 GLU B 79 +REMARK 465 PRO B 80 +REMARK 465 ALA B 81 +REMARK 465 GLY B 82 +REMARK 465 GLY B 83 +REMARK 465 SER B 84 +REMARK 465 HIS B 85 +REMARK 465 SER B 86 +REMARK 465 GLY B 87 +REMARK 465 SER B 88 +REMARK 465 ARG B 141 +REMARK 465 GLU B 142 +REMARK 465 GLN B 143 +REMARK 465 MET B 144 +REMARK 465 ASN B 145 +REMARK 465 LEU B 146 +REMARK 465 THR B 147 +REMARK 465 SER B 148 +REMARK 465 LEU B 149 +REMARK 465 ASP B 150 +REMARK 465 VAL B 527 +REMARK 465 GLU B 528 +REMARK 465 GLN B 529 +REMARK 465 MET D 1 +REMARK 465 ILE D 2 +REMARK 465 LEU D 3 +REMARK 465 PHE D 4 +REMARK 465 ARG D 5 +REMARK 465 LYS D 6 +REMARK 465 PHE D 7 +REMARK 465 ARG D 8 +REMARK 465 VAL D 9 +REMARK 465 LEU D 10 +REMARK 465 ILE D 11 +REMARK 465 LEU D 12 +REMARK 465 THR D 13 +REMARK 465 VAL D 14 +REMARK 465 PHE D 15 +REMARK 465 LEU D 16 +REMARK 465 ILE D 17 +REMARK 465 ALA D 18 +REMARK 465 CYS D 19 +REMARK 465 THR D 20 +REMARK 465 MET D 21 +REMARK 465 HIS D 22 +REMARK 465 ILE D 23 +REMARK 465 MET D 24 +REMARK 465 ILE D 25 +REMARK 465 ASP D 26 +REMARK 465 LEU D 27 +REMARK 465 LEU D 28 +REMARK 465 PRO D 29 +REMARK 465 LYS D 30 +REMARK 465 LEU D 31 +REMARK 465 GLU D 32 +REMARK 465 LYS D 33 +REMARK 465 ARG D 34 +REMARK 465 ALA D 35 +REMARK 465 ALA D 36 +REMARK 465 GLY D 37 +REMARK 465 SER D 38 +REMARK 465 SER D 39 +REMARK 465 SER D 40 +REMARK 465 SER D 41 +REMARK 465 ALA D 42 +REMARK 465 GLY D 43 +REMARK 465 GLY D 44 +REMARK 465 GLY D 45 +REMARK 465 SER D 46 +REMARK 465 GLY D 47 +REMARK 465 CYS D 48 +REMARK 465 SER D 49 +REMARK 465 CYS D 50 +REMARK 465 ALA D 51 +REMARK 465 HIS D 52 +REMARK 465 THR D 53 +REMARK 465 PRO D 54 +REMARK 465 GLY D 55 +REMARK 465 GLU D 56 +REMARK 465 GLU D 57 +REMARK 465 PRO D 58 +REMARK 465 ARG D 59 +REMARK 465 SER D 60 +REMARK 465 TRP D 61 +REMARK 465 GLY D 62 +REMARK 465 LYS D 63 +REMARK 465 GLN D 64 +REMARK 465 ARG D 65 +REMARK 465 ALA D 66 +REMARK 465 ARG D 67 +REMARK 465 ALA D 68 +REMARK 465 ALA D 69 +REMARK 465 ASP D 70 +REMARK 465 PRO D 71 +REMARK 465 GLY D 72 +REMARK 465 TRP D 73 +REMARK 465 PRO D 74 +REMARK 465 ASN D 75 +REMARK 465 LYS D 76 +REMARK 465 HIS D 77 +REMARK 465 SER D 78 +REMARK 465 LEU D 79 +REMARK 465 ARG D 80 +REMARK 465 LEU D 81 +REMARK 465 LEU D 82 +REMARK 465 GLN D 83 +REMARK 465 ASP D 84 +REMARK 465 PHE D 85 +REMARK 465 SER D 86 +REMARK 465 ASN D 87 +REMARK 465 GLU D 88 +REMARK 465 PRO D 89 +REMARK 465 ASN D 90 +REMARK 465 SER D 91 +REMARK 465 ASN D 92 +REMARK 465 LEU D 93 +REMARK 465 THR D 94 +REMARK 465 SER D 95 +REMARK 465 GLN D 96 +REMARK 465 SER D 97 +REMARK 465 ARG D 98 +REMARK 465 GLU D 99 +REMARK 465 LYS D 100 +REMARK 465 VAL D 101 +REMARK 465 THR D 102 +REMARK 465 GLU D 103 +REMARK 465 ARG D 104 +REMARK 465 ALA D 105 +REMARK 465 GLY D 106 +REMARK 465 SER D 107 +REMARK 465 GLU D 108 +REMARK 465 LYS D 109 +REMARK 465 GLN D 110 +REMARK 465 GLY D 111 +REMARK 465 SER D 112 +REMARK 465 GLY D 113 +REMARK 465 LYS D 114 +REMARK 465 ARG D 115 +REMARK 465 GLY D 116 +REMARK 465 LEU D 117 +REMARK 465 MET D 118 +REMARK 465 ARG D 119 +REMARK 465 GLU D 120 +REMARK 465 ALA D 121 +REMARK 465 ASP D 122 +REMARK 465 SER D 123 +REMARK 465 ARG D 124 +REMARK 465 GLN D 125 +REMARK 465 ARG D 126 +REMARK 465 ARG D 127 +REMARK 465 THR D 128 +REMARK 465 ASP D 129 +REMARK 465 VAL D 130 +REMARK 465 ARG D 131 +REMARK 465 VAL D 132 +REMARK 465 SER D 133 +REMARK 465 ALA D 172 +REMARK 465 GLY D 173 +REMARK 465 GLN D 174 +REMARK 465 GLN D 175 +REMARK 465 GLU D 176 +REMARK 465 TRP D 177 +REMARK 465 HIS D 178 +REMARK 465 ASN D 179 +REMARK 465 GLU D 180 +REMARK 465 GLY D 181 +REMARK 465 ASN D 182 +REMARK 465 VAL D 183 +REMARK 465 GLU D 184 +REMARK 465 GLU D 185 +REMARK 465 GLU D 186 +REMARK 465 GLU D 187 +REMARK 465 PHE D 188 +REMARK 465 SER D 189 +REMARK 465 PRO D 190 +REMARK 465 PRO D 191 +REMARK 465 GLY D 192 +REMARK 465 GLU D 193 +REMARK 465 ALA D 194 +REMARK 465 ASN D 195 +REMARK 465 SER D 196 +REMARK 465 GLN D 553 +REMARK 465 PRO D 554 +REMARK 465 SER D 555 +REMARK 465 VAL D 556 +REMARK 465 HIS D 557 +REMARK 465 GLY D 558 +REMARK 465 GLY D 559 +REMARK 465 ARG D 560 +REMARK 500 +REMARK 500 GEOMETRY AND STEREOCHEMISTRY +REMARK 500 SUBTOPIC: TORSION ANGLES +REMARK 500 +REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: +REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; +REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). +REMARK 500 +REMARK 500 STANDARD TABLE: +REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) +REMARK 500 +REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- +REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 +REMARK 500 +REMARK 500 M RES CSSEQI PSI PHI +REMARK 500 SER A 90 86.89 59.08 +REMARK 500 TYR A 101 33.52 -84.21 +REMARK 500 ASN A 102 -20.34 -149.38 +REMARK 500 ALA A 112 -69.52 56.98 +REMARK 500 ARG A 135 -84.04 -70.49 +REMARK 500 ARG A 136 -44.14 -18.11 +REMARK 500 SER A 199 163.42 66.81 +REMARK 500 GLN A 200 -162.61 -73.58 +REMARK 500 ASP A 201 -43.90 64.73 +REMARK 500 GLU A 202 -159.36 -84.59 +REMARK 500 LYS A 203 -52.54 62.48 +REMARK 500 LEU A 206 -70.00 63.18 +REMARK 500 ALA A 208 73.71 -159.64 +REMARK 500 VAL A 215 73.99 -108.73 +REMARK 500 VAL A 220 43.72 -97.91 +REMARK 500 PHE A 231 -10.25 78.77 +REMARK 500 ASP A 250 10.36 81.85 +REMARK 500 PHE A 257 -166.18 -73.54 +REMARK 500 ILE A 292 -59.96 -129.86 +REMARK 500 TYR A 327 -166.79 -103.83 +REMARK 500 SER A 390 19.41 59.20 +REMARK 500 TYR A 471 52.28 -141.17 +REMARK 500 ASP A 524 46.66 -83.15 +REMARK 500 THR C 147 105.37 -59.14 +REMARK 500 PRO C 150 172.89 -57.94 +REMARK 500 THR C 153 149.54 -170.43 +REMARK 500 LEU C 161 -48.28 -5.20 +REMARK 500 ASN C 162 -9.21 -59.85 +REMARK 500 ALA C 171 166.78 62.77 +REMARK 500 GLU C 197 46.61 -88.40 +REMARK 500 TYR C 212 -78.48 -91.01 +REMARK 500 HIS C 218 69.20 -117.25 +REMARK 500 TYR C 255 -4.02 64.06 +REMARK 500 LYS C 264 -41.28 71.83 +REMARK 500 ILE C 316 -66.54 -126.73 +REMARK 500 ARG C 327 1.11 -69.23 +REMARK 500 CYS C 343 -128.91 -93.49 +REMARK 500 SER C 344 -34.38 -137.26 +REMARK 500 CYS C 347 69.87 -114.66 +REMARK 500 ASP C 358 39.47 -153.57 +REMARK 500 GLU C 361 147.47 71.53 +REMARK 500 LEU C 371 -8.22 -59.50 +REMARK 500 ALA C 374 61.34 -154.93 +REMARK 500 ARG C 390 -56.97 71.93 +REMARK 500 LYS C 392 -167.91 -79.79 +REMARK 500 ARG C 413 -155.21 -144.00 +REMARK 500 THR C 415 -54.26 77.36 +REMARK 500 LEU C 417 -58.39 62.25 +REMARK 500 THR C 440 -144.35 -137.50 +REMARK 500 GLU C 442 -64.88 59.94 +REMARK 500 +REMARK 500 THIS ENTRY HAS 106 RAMACHANDRAN OUTLIERS. +REMARK 500 +REMARK 500 REMARK: NULL +REMARK 500 +REMARK 500 GEOMETRY AND STEREOCHEMISTRY +REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS +REMARK 500 +REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH +REMARK 500 CIS AND TRANS CONFORMATION. CIS BONDS, IF ANY, ARE LISTED +REMARK 500 ON CISPEP RECORDS. TRANS IS DEFINED AS 180 +/- 30 AND +REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES. +REMARK 500 MODEL OMEGA +REMARK 500 ASP B 201 GLU B 202 149.52 +REMARK 500 +REMARK 500 REMARK: NULL +REMARK 800 +REMARK 800 SITE +REMARK 800 SITE_IDENTIFIER: AC1 +REMARK 800 EVIDENCE_CODE: SOFTWARE +REMARK 800 SITE_DESCRIPTION: binding site for residue ATP A 701 +REMARK 800 +REMARK 800 SITE_IDENTIFIER: AC2 +REMARK 800 EVIDENCE_CODE: SOFTWARE +REMARK 800 SITE_DESCRIPTION: binding site for residue ATP B 701 +DBREF 5YH2 A 63 529 UNP Q96MK3 FA20A_HUMAN 63 529 +DBREF 5YH2 C 1 560 UNP E7FBB8 E7FBB8_DANRE 1 560 +DBREF 5YH2 B 63 529 UNP Q96MK3 FA20A_HUMAN 63 529 +DBREF 5YH2 D 1 560 UNP E7FBB8 E7FBB8_DANRE 1 560 +SEQADV 5YH2 LYS A 332 UNP Q96MK3 ASN 332 VARIANT +SEQADV 5YH2 ALA C 223 UNP E7FBB8 THR 223 ENGINEERED MUTATION +SEQADV 5YH2 MET C 421 UNP E7FBB8 LYS 421 ENGINEERED MUTATION +SEQADV 5YH2 ASP C 422 UNP E7FBB8 ALA 422 ENGINEERED MUTATION +SEQADV 5YH2 MET C 423 UNP E7FBB8 LEU 423 ENGINEERED MUTATION +SEQADV 5YH2 ILE C 425 UNP E7FBB8 HIS 425 ENGINEERED MUTATION +SEQADV 5YH2 PHE C 426 UNP E7FBB8 TYR 426 ENGINEERED MUTATION +SEQADV 5YH2 ASP C 427 UNP E7FBB8 SER 427 ENGINEERED MUTATION +SEQADV 5YH2 PHE C 428 UNP E7FBB8 LEU 428 ENGINEERED MUTATION +SEQADV 5YH2 LEU C 429 UNP E7FBB8 LYS 429 ENGINEERED MUTATION +SEQADV 5YH2 MET C 430 UNP E7FBB8 THR 430 ENGINEERED MUTATION +SEQADV 5YH2 LYS B 332 UNP Q96MK3 ASN 332 VARIANT +SEQADV 5YH2 ALA D 223 UNP E7FBB8 THR 223 ENGINEERED MUTATION +SEQADV 5YH2 MET D 421 UNP E7FBB8 LYS 421 ENGINEERED MUTATION +SEQADV 5YH2 ASP D 422 UNP E7FBB8 ALA 422 ENGINEERED MUTATION +SEQADV 5YH2 MET D 423 UNP E7FBB8 LEU 423 ENGINEERED MUTATION +SEQADV 5YH2 ILE D 425 UNP E7FBB8 HIS 425 ENGINEERED MUTATION +SEQADV 5YH2 PHE D 426 UNP E7FBB8 TYR 426 ENGINEERED MUTATION +SEQADV 5YH2 ASP D 427 UNP E7FBB8 SER 427 ENGINEERED MUTATION +SEQADV 5YH2 PHE D 428 UNP E7FBB8 LEU 428 ENGINEERED MUTATION +SEQADV 5YH2 LEU D 429 UNP E7FBB8 LYS 429 ENGINEERED MUTATION +SEQADV 5YH2 MET D 430 UNP E7FBB8 THR 430 ENGINEERED MUTATION +SEQRES 1 A 467 ASP PRO GLY THR ILE VAL HIS ASN PHE SER ARG THR GLU +SEQRES 2 A 467 PRO ARG THR GLU PRO ALA GLY GLY SER HIS SER GLY SER +SEQRES 3 A 467 SER SER LYS LEU GLN ALA LEU PHE ALA HIS PRO LEU TYR +SEQRES 4 A 467 ASN VAL PRO GLU GLU PRO PRO LEU LEU GLY ALA GLU ASP +SEQRES 5 A 467 SER LEU LEU ALA SER GLN GLU ALA LEU ARG TYR TYR ARG +SEQRES 6 A 467 ARG LYS VAL ALA ARG TRP ASN ARG ARG HIS LYS MET TYR +SEQRES 7 A 467 ARG GLU GLN MET ASN LEU THR SER LEU ASP PRO PRO LEU +SEQRES 8 A 467 GLN LEU ARG LEU GLU ALA SER TRP VAL GLN PHE HIS LEU +SEQRES 9 A 467 GLY ILE ASN ARG HIS GLY LEU TYR SER ARG SER SER PRO +SEQRES 10 A 467 VAL VAL SER LYS LEU LEU GLN ASP MET ARG HIS PHE PRO +SEQRES 11 A 467 THR ILE SER ALA ASP TYR SER GLN ASP GLU LYS ALA LEU +SEQRES 12 A 467 LEU GLY ALA CYS ASP CYS THR GLN ILE VAL LYS PRO SER +SEQRES 13 A 467 GLY VAL HIS LEU LYS LEU VAL LEU ARG PHE SER ASP PHE +SEQRES 14 A 467 GLY LYS ALA MET PHE LYS PRO MET ARG GLN GLN ARG ASP +SEQRES 15 A 467 GLU GLU THR PRO VAL ASP PHE PHE TYR PHE ILE ASP PHE +SEQRES 16 A 467 GLN ARG HIS ASN ALA GLU ILE ALA ALA PHE HIS LEU ASP +SEQRES 17 A 467 ARG ILE LEU ASP PHE ARG ARG VAL PRO PRO THR VAL GLY +SEQRES 18 A 467 ARG ILE VAL ASN VAL THR LYS GLU ILE LEU GLU VAL THR +SEQRES 19 A 467 LYS ASN GLU ILE LEU GLN SER VAL PHE PHE VAL SER PRO +SEQRES 20 A 467 ALA SER ASN VAL CYS PHE PHE ALA LYS CYS PRO TYR MET +SEQRES 21 A 467 CYS LYS THR GLU TYR ALA VAL CYS GLY LYS PRO HIS LEU +SEQRES 22 A 467 LEU GLU GLY SER LEU SER ALA PHE LEU PRO SER LEU ASN +SEQRES 23 A 467 LEU ALA PRO ARG LEU SER VAL PRO ASN PRO TRP ILE ARG +SEQRES 24 A 467 SER TYR THR LEU ALA GLY LYS GLU GLU TRP GLU VAL ASN +SEQRES 25 A 467 PRO LEU TYR CYS ASP THR VAL LYS GLN ILE TYR PRO TYR +SEQRES 26 A 467 ASN ASN SER GLN ARG LEU LEU ASN VAL ILE ASP MET ALA +SEQRES 27 A 467 ILE PHE ASP PHE LEU ILE GLY ASN MET ASP ARG HIS HIS +SEQRES 28 A 467 TYR GLU MET PHE THR LYS PHE GLY ASP ASP GLY PHE LEU +SEQRES 29 A 467 ILE HIS LEU ASP ASN ALA ARG GLY PHE GLY ARG HIS SER +SEQRES 30 A 467 HIS ASP GLU ILE SER ILE LEU SER PRO LEU SER GLN CYS +SEQRES 31 A 467 CYS MET ILE LYS LYS LYS THR LEU LEU HIS LEU GLN LEU +SEQRES 32 A 467 LEU ALA GLN ALA ASP TYR ARG LEU SER ASP VAL MET ARG +SEQRES 33 A 467 GLU SER LEU LEU GLU ASP GLN LEU SER PRO VAL LEU THR +SEQRES 34 A 467 GLU PRO HIS LEU LEU ALA LEU ASP ARG ARG LEU GLN THR +SEQRES 35 A 467 ILE LEU ARG THR VAL GLU GLY CYS ILE VAL ALA HIS GLY +SEQRES 36 A 467 GLN GLN SER VAL ILE VAL ASP GLY PRO VAL GLU GLN +SEQRES 1 C 560 MET ILE LEU PHE ARG LYS PHE ARG VAL LEU ILE LEU THR +SEQRES 2 C 560 VAL PHE LEU ILE ALA CYS THR MET HIS ILE MET ILE ASP +SEQRES 3 C 560 LEU LEU PRO LYS LEU GLU LYS ARG ALA ALA GLY SER SER +SEQRES 4 C 560 SER SER ALA GLY GLY GLY SER GLY CYS SER CYS ALA HIS +SEQRES 5 C 560 THR PRO GLY GLU GLU PRO ARG SER TRP GLY LYS GLN ARG +SEQRES 6 C 560 ALA ARG ALA ALA ASP PRO GLY TRP PRO ASN LYS HIS SER +SEQRES 7 C 560 LEU ARG LEU LEU GLN ASP PHE SER ASN GLU PRO ASN SER +SEQRES 8 C 560 ASN LEU THR SER GLN SER ARG GLU LYS VAL THR GLU ARG +SEQRES 9 C 560 ALA GLY SER GLU LYS GLN GLY SER GLY LYS ARG GLY LEU +SEQRES 10 C 560 MET ARG GLU ALA ASP SER ARG GLN ARG ARG THR ASP VAL +SEQRES 11 C 560 ARG VAL SER SER VAL LEU GLN SER LEU PHE GLU HIS PRO +SEQRES 12 C 560 LEU TYR ARG THR VAL LEU PRO ASP LEU THR GLU GLU ASP +SEQRES 13 C 560 THR LEU PHE ASN LEU ASN ALA GLU ILE ARG LEU TYR PRO +SEQRES 14 C 560 LYS ALA ALA GLY GLN GLN GLU TRP HIS ASN GLU GLY ASN +SEQRES 15 C 560 VAL GLU GLU GLU GLU PHE SER PRO PRO GLY GLU ALA ASN +SEQRES 16 C 560 SER GLU SER TYR PRO ASN TRP LEU ARG PHE HIS ILE GLY +SEQRES 17 C 560 ILE ASN ARG TYR GLU LEU TYR SER ARG HIS ASN PRO VAL +SEQRES 18 C 560 ILE ALA ALA LEU LEU ARG ASP LEU LEU SER GLN LYS ILE +SEQRES 19 C 560 SER SER VAL GLY MET LYS SER GLY GLY THR GLN LEU LYS +SEQRES 20 C 560 LEU ILE MET SER PHE GLN ASN TYR GLY GLN ALA LEU PHE +SEQRES 21 C 560 LYS PRO MET LYS GLN THR ARG GLU GLN GLU THR PRO PRO +SEQRES 22 C 560 ASP PHE PHE TYR PHE SER ASP PHE GLU ARG HIS ASN ALA +SEQRES 23 C 560 GLU ILE ALA ALA PHE HIS LEU ASP ARG ILE LEU ASP PHE +SEQRES 24 C 560 ARG ARG VAL PRO PRO VAL ALA GLY ARG LEU VAL ASN MET +SEQRES 25 C 560 THR ARG GLU ILE ARG ASP VAL THR ARG ASP LYS LYS LEU +SEQRES 26 C 560 TRP ARG THR PHE PHE VAL SER PRO ALA ASN ASN ILE CYS +SEQRES 27 C 560 PHE TYR GLY GLU CYS SER TYR TYR CYS SER THR GLU HIS +SEQRES 28 C 560 ALA LEU CYS GLY LYS PRO ASP GLN ILE GLU GLY SER LEU +SEQRES 29 C 560 ALA ALA PHE LEU PRO ASP LEU ALA LEU ALA LYS ARG LYS +SEQRES 30 C 560 THR TRP ARG ASN PRO TRP ARG ARG SER TYR HIS LYS ARG +SEQRES 31 C 560 LYS LYS ALA GLU TRP GLU VAL ASP PRO ASP TYR CYS ASP +SEQRES 32 C 560 GLU VAL LYS GLN THR PRO PRO TYR ASP ARG GLY THR ARG +SEQRES 33 C 560 LEU LEU ASP ILE MET ASP MET THR ILE PHE ASP PHE LEU +SEQRES 34 C 560 MET GLY ASN MET ASP ARG HIS HIS TYR GLU THR PHE GLU +SEQRES 35 C 560 LYS PHE GLY ASN ASP THR PHE ILE ILE HIS LEU ASP ASN +SEQRES 36 C 560 GLY ARG GLY PHE GLY LYS HIS SER HIS ASP GLU MET SER +SEQRES 37 C 560 ILE LEU VAL PRO LEU THR GLN CYS CYS ARG VAL LYS ARG +SEQRES 38 C 560 SER THR TYR LEU ARG LEU GLN LEU LEU ALA LYS GLU GLU +SEQRES 39 C 560 TYR LYS LEU SER SER LEU MET GLU GLU SER LEU LEU GLN +SEQRES 40 C 560 ASP ARG LEU VAL PRO VAL LEU ILE LYS PRO HIS LEU GLU +SEQRES 41 C 560 ALA LEU ASP ARG ARG LEU ARG LEU VAL LEU LYS VAL LEU +SEQRES 42 C 560 SER ASP CYS VAL GLU LYS ASP GLY PHE SER ALA VAL VAL +SEQRES 43 C 560 GLU ASN ASP LEU ASP GLY GLN PRO SER VAL HIS GLY GLY +SEQRES 44 C 560 ARG +SEQRES 1 B 467 ASP PRO GLY THR ILE VAL HIS ASN PHE SER ARG THR GLU +SEQRES 2 B 467 PRO ARG THR GLU PRO ALA GLY GLY SER HIS SER GLY SER +SEQRES 3 B 467 SER SER LYS LEU GLN ALA LEU PHE ALA HIS PRO LEU TYR +SEQRES 4 B 467 ASN VAL PRO GLU GLU PRO PRO LEU LEU GLY ALA GLU ASP +SEQRES 5 B 467 SER LEU LEU ALA SER GLN GLU ALA LEU ARG TYR TYR ARG +SEQRES 6 B 467 ARG LYS VAL ALA ARG TRP ASN ARG ARG HIS LYS MET TYR +SEQRES 7 B 467 ARG GLU GLN MET ASN LEU THR SER LEU ASP PRO PRO LEU +SEQRES 8 B 467 GLN LEU ARG LEU GLU ALA SER TRP VAL GLN PHE HIS LEU +SEQRES 9 B 467 GLY ILE ASN ARG HIS GLY LEU TYR SER ARG SER SER PRO +SEQRES 10 B 467 VAL VAL SER LYS LEU LEU GLN ASP MET ARG HIS PHE PRO +SEQRES 11 B 467 THR ILE SER ALA ASP TYR SER GLN ASP GLU LYS ALA LEU +SEQRES 12 B 467 LEU GLY ALA CYS ASP CYS THR GLN ILE VAL LYS PRO SER +SEQRES 13 B 467 GLY VAL HIS LEU LYS LEU VAL LEU ARG PHE SER ASP PHE +SEQRES 14 B 467 GLY LYS ALA MET PHE LYS PRO MET ARG GLN GLN ARG ASP +SEQRES 15 B 467 GLU GLU THR PRO VAL ASP PHE PHE TYR PHE ILE ASP PHE +SEQRES 16 B 467 GLN ARG HIS ASN ALA GLU ILE ALA ALA PHE HIS LEU ASP +SEQRES 17 B 467 ARG ILE LEU ASP PHE ARG ARG VAL PRO PRO THR VAL GLY +SEQRES 18 B 467 ARG ILE VAL ASN VAL THR LYS GLU ILE LEU GLU VAL THR +SEQRES 19 B 467 LYS ASN GLU ILE LEU GLN SER VAL PHE PHE VAL SER PRO +SEQRES 20 B 467 ALA SER ASN VAL CYS PHE PHE ALA LYS CYS PRO TYR MET +SEQRES 21 B 467 CYS LYS THR GLU TYR ALA VAL CYS GLY LYS PRO HIS LEU +SEQRES 22 B 467 LEU GLU GLY SER LEU SER ALA PHE LEU PRO SER LEU ASN +SEQRES 23 B 467 LEU ALA PRO ARG LEU SER VAL PRO ASN PRO TRP ILE ARG +SEQRES 24 B 467 SER TYR THR LEU ALA GLY LYS GLU GLU TRP GLU VAL ASN +SEQRES 25 B 467 PRO LEU TYR CYS ASP THR VAL LYS GLN ILE TYR PRO TYR +SEQRES 26 B 467 ASN ASN SER GLN ARG LEU LEU ASN VAL ILE ASP MET ALA +SEQRES 27 B 467 ILE PHE ASP PHE LEU ILE GLY ASN MET ASP ARG HIS HIS +SEQRES 28 B 467 TYR GLU MET PHE THR LYS PHE GLY ASP ASP GLY PHE LEU +SEQRES 29 B 467 ILE HIS LEU ASP ASN ALA ARG GLY PHE GLY ARG HIS SER +SEQRES 30 B 467 HIS ASP GLU ILE SER ILE LEU SER PRO LEU SER GLN CYS +SEQRES 31 B 467 CYS MET ILE LYS LYS LYS THR LEU LEU HIS LEU GLN LEU +SEQRES 32 B 467 LEU ALA GLN ALA ASP TYR ARG LEU SER ASP VAL MET ARG +SEQRES 33 B 467 GLU SER LEU LEU GLU ASP GLN LEU SER PRO VAL LEU THR +SEQRES 34 B 467 GLU PRO HIS LEU LEU ALA LEU ASP ARG ARG LEU GLN THR +SEQRES 35 B 467 ILE LEU ARG THR VAL GLU GLY CYS ILE VAL ALA HIS GLY +SEQRES 36 B 467 GLN GLN SER VAL ILE VAL ASP GLY PRO VAL GLU GLN +SEQRES 1 D 560 MET ILE LEU PHE ARG LYS PHE ARG VAL LEU ILE LEU THR +SEQRES 2 D 560 VAL PHE LEU ILE ALA CYS THR MET HIS ILE MET ILE ASP +SEQRES 3 D 560 LEU LEU PRO LYS LEU GLU LYS ARG ALA ALA GLY SER SER +SEQRES 4 D 560 SER SER ALA GLY GLY GLY SER GLY CYS SER CYS ALA HIS +SEQRES 5 D 560 THR PRO GLY GLU GLU PRO ARG SER TRP GLY LYS GLN ARG +SEQRES 6 D 560 ALA ARG ALA ALA ASP PRO GLY TRP PRO ASN LYS HIS SER +SEQRES 7 D 560 LEU ARG LEU LEU GLN ASP PHE SER ASN GLU PRO ASN SER +SEQRES 8 D 560 ASN LEU THR SER GLN SER ARG GLU LYS VAL THR GLU ARG +SEQRES 9 D 560 ALA GLY SER GLU LYS GLN GLY SER GLY LYS ARG GLY LEU +SEQRES 10 D 560 MET ARG GLU ALA ASP SER ARG GLN ARG ARG THR ASP VAL +SEQRES 11 D 560 ARG VAL SER SER VAL LEU GLN SER LEU PHE GLU HIS PRO +SEQRES 12 D 560 LEU TYR ARG THR VAL LEU PRO ASP LEU THR GLU GLU ASP +SEQRES 13 D 560 THR LEU PHE ASN LEU ASN ALA GLU ILE ARG LEU TYR PRO +SEQRES 14 D 560 LYS ALA ALA GLY GLN GLN GLU TRP HIS ASN GLU GLY ASN +SEQRES 15 D 560 VAL GLU GLU GLU GLU PHE SER PRO PRO GLY GLU ALA ASN +SEQRES 16 D 560 SER GLU SER TYR PRO ASN TRP LEU ARG PHE HIS ILE GLY +SEQRES 17 D 560 ILE ASN ARG TYR GLU LEU TYR SER ARG HIS ASN PRO VAL +SEQRES 18 D 560 ILE ALA ALA LEU LEU ARG ASP LEU LEU SER GLN LYS ILE +SEQRES 19 D 560 SER SER VAL GLY MET LYS SER GLY GLY THR GLN LEU LYS +SEQRES 20 D 560 LEU ILE MET SER PHE GLN ASN TYR GLY GLN ALA LEU PHE +SEQRES 21 D 560 LYS PRO MET LYS GLN THR ARG GLU GLN GLU THR PRO PRO +SEQRES 22 D 560 ASP PHE PHE TYR PHE SER ASP PHE GLU ARG HIS ASN ALA +SEQRES 23 D 560 GLU ILE ALA ALA PHE HIS LEU ASP ARG ILE LEU ASP PHE +SEQRES 24 D 560 ARG ARG VAL PRO PRO VAL ALA GLY ARG LEU VAL ASN MET +SEQRES 25 D 560 THR ARG GLU ILE ARG ASP VAL THR ARG ASP LYS LYS LEU +SEQRES 26 D 560 TRP ARG THR PHE PHE VAL SER PRO ALA ASN ASN ILE CYS +SEQRES 27 D 560 PHE TYR GLY GLU CYS SER TYR TYR CYS SER THR GLU HIS +SEQRES 28 D 560 ALA LEU CYS GLY LYS PRO ASP GLN ILE GLU GLY SER LEU +SEQRES 29 D 560 ALA ALA PHE LEU PRO ASP LEU ALA LEU ALA LYS ARG LYS +SEQRES 30 D 560 THR TRP ARG ASN PRO TRP ARG ARG SER TYR HIS LYS ARG +SEQRES 31 D 560 LYS LYS ALA GLU TRP GLU VAL ASP PRO ASP TYR CYS ASP +SEQRES 32 D 560 GLU VAL LYS GLN THR PRO PRO TYR ASP ARG GLY THR ARG +SEQRES 33 D 560 LEU LEU ASP ILE MET ASP MET THR ILE PHE ASP PHE LEU +SEQRES 34 D 560 MET GLY ASN MET ASP ARG HIS HIS TYR GLU THR PHE GLU +SEQRES 35 D 560 LYS PHE GLY ASN ASP THR PHE ILE ILE HIS LEU ASP ASN +SEQRES 36 D 560 GLY ARG GLY PHE GLY LYS HIS SER HIS ASP GLU MET SER +SEQRES 37 D 560 ILE LEU VAL PRO LEU THR GLN CYS CYS ARG VAL LYS ARG +SEQRES 38 D 560 SER THR TYR LEU ARG LEU GLN LEU LEU ALA LYS GLU GLU +SEQRES 39 D 560 TYR LYS LEU SER SER LEU MET GLU GLU SER LEU LEU GLN +SEQRES 40 D 560 ASP ARG LEU VAL PRO VAL LEU ILE LYS PRO HIS LEU GLU +SEQRES 41 D 560 ALA LEU ASP ARG ARG LEU ARG LEU VAL LEU LYS VAL LEU +SEQRES 42 D 560 SER ASP CYS VAL GLU LYS ASP GLY PHE SER ALA VAL VAL +SEQRES 43 D 560 GLU ASN ASP LEU ASP GLY GLN PRO SER VAL HIS GLY GLY +SEQRES 44 D 560 ARG +HET ATP A 701 31 +HET ATP B 701 31 +HETNAM ATP ADENOSINE-5'-TRIPHOSPHATE +FORMUL 5 ATP 2(C10 H16 N5 O13 P3) +HELIX 1 AA1 SER A 90 ALA A 97 1 8 +HELIX 2 AA2 HIS A 98 ASN A 102 5 5 +HELIX 3 AA3 ALA A 118 MET A 139 1 22 +HELIX 4 AA4 ALA A 159 GLY A 167 1 9 +HELIX 5 AA5 SER A 178 PHE A 191 1 14 +HELIX 6 AA6 PHE A 252 ASP A 256 5 5 +HELIX 7 AA7 ARG A 259 LEU A 273 1 15 +HELIX 8 AA8 ILE A 292 THR A 296 5 5 +HELIX 9 AA9 ASN A 298 VAL A 304 1 7 +HELIX 10 AB1 ALA A 317 CYS A 323 1 7 +HELIX 11 AB2 LEU A 376 LYS A 382 1 7 +HELIX 12 AB3 PRO A 386 SER A 390 5 5 +HELIX 13 AB4 GLN A 391 GLY A 407 1 17 +HELIX 14 AB5 LYS A 419 GLY A 421 5 3 +HELIX 15 AB6 GLU A 442 ILE A 445 5 4 +HELIX 16 AB7 LEU A 446 CYS A 453 1 8 +HELIX 17 AB8 LYS A 457 LEU A 466 1 10 +HELIX 18 AB9 ALA A 467 TYR A 471 5 5 +HELIX 19 AC1 ARG A 472 LEU A 481 1 10 +HELIX 20 AC2 LEU A 482 ASP A 484 5 3 +HELIX 21 AC3 THR A 491 VAL A 521 1 31 +HELIX 22 AC4 VAL C 135 HIS C 142 1 8 +HELIX 23 AC5 ASN C 160 GLU C 164 5 5 +HELIX 24 AC6 PRO C 200 GLY C 208 1 9 +HELIX 25 AC7 ASN C 219 GLN C 232 1 14 +HELIX 26 AC8 PHE C 276 ASP C 280 5 5 +HELIX 27 AC9 ARG C 283 LEU C 297 1 15 +HELIX 28 AD1 ILE C 316 THR C 320 5 5 +HELIX 29 AD2 ASP C 322 ARG C 327 1 6 +HELIX 30 AD3 SER C 348 ALA C 352 5 5 +HELIX 31 AD4 ALA C 393 VAL C 397 5 5 +HELIX 32 AD5 ASP C 400 LYS C 406 1 7 +HELIX 33 AD6 LEU C 417 GLY C 431 1 15 +HELIX 34 AD7 GLU C 466 ILE C 469 5 4 +HELIX 35 AD8 LEU C 470 CYS C 477 1 8 +HELIX 36 AD9 ARG C 481 LEU C 490 1 10 +HELIX 37 AE1 LEU C 497 LEU C 506 1 10 +HELIX 38 AE2 ILE C 515 GLY C 541 1 27 +HELIX 39 AE3 SER B 90 ALA B 97 1 8 +HELIX 40 AE4 HIS B 98 VAL B 103 5 6 +HELIX 41 AE5 ALA B 118 TYR B 140 1 23 +HELIX 42 AE6 ALA B 159 GLY B 167 1 9 +HELIX 43 AE7 SER B 178 PHE B 191 1 14 +HELIX 44 AE8 PHE B 252 ASP B 256 5 5 +HELIX 45 AE9 ARG B 259 LEU B 273 1 15 +HELIX 46 AF1 ILE B 292 THR B 296 5 5 +HELIX 47 AF2 ASN B 298 VAL B 304 1 7 +HELIX 48 AF3 ALA B 317 CYS B 323 1 7 +HELIX 49 AF4 GLU B 369 ASN B 374 1 6 +HELIX 50 AF5 LEU B 376 LYS B 382 1 7 +HELIX 51 AF6 GLN B 391 GLY B 407 1 17 +HELIX 52 AF7 LYS B 419 GLY B 421 5 3 +HELIX 53 AF8 GLU B 442 ILE B 445 5 4 +HELIX 54 AF9 LEU B 446 CYS B 453 1 8 +HELIX 55 AG1 LYS B 457 LEU B 466 1 10 +HELIX 56 AG2 ALA B 467 TYR B 471 5 5 +HELIX 57 AG3 ARG B 472 LEU B 481 1 10 +HELIX 58 AG4 LEU B 482 ASP B 484 5 3 +HELIX 59 AG5 THR B 491 VAL B 521 1 31 +HELIX 60 AG6 VAL D 135 HIS D 142 1 8 +HELIX 61 AG7 ASN D 160 GLU D 164 5 5 +HELIX 62 AG8 PRO D 200 GLY D 208 1 9 +HELIX 63 AG9 ASN D 219 GLN D 232 1 14 +HELIX 64 AH1 ARG D 283 LEU D 297 1 15 +HELIX 65 AH2 ILE D 316 THR D 320 5 5 +HELIX 66 AH3 ASP D 322 ARG D 327 1 6 +HELIX 67 AH4 SER D 348 ALA D 352 5 5 +HELIX 68 AH5 ALA D 393 VAL D 397 5 5 +HELIX 69 AH6 ASP D 400 LYS D 406 1 7 +HELIX 70 AH7 LEU D 417 GLY D 431 1 15 +HELIX 71 AH8 GLU D 466 ILE D 469 5 4 +HELIX 72 AH9 LEU D 470 CYS D 477 1 8 +HELIX 73 AI1 ARG D 481 LEU D 490 1 10 +HELIX 74 AI2 LEU D 497 LEU D 505 1 9 +HELIX 75 AI3 ILE D 515 GLY D 541 1 27 +SHEET 1 AA1 5 THR A 193 ASP A 197 0 +SHEET 2 AA1 5 LEU A 224 PHE A 228 -1 O ARG A 227 N ILE A 194 +SHEET 3 AA1 5 LYS A 233 PRO A 238 -1 O PHE A 236 N LEU A 224 +SHEET 4 AA1 5 LEU A 335 ALA A 342 -1 O SER A 341 N MET A 235 +SHEET 5 AA1 5 THR A 281 ASN A 287 -1 N VAL A 286 O LEU A 336 +SHEET 1 AA2 3 PHE A 306 VAL A 307 0 +SHEET 2 AA2 3 VAL A 313 PHE A 315 -1 O CYS A 314 N PHE A 306 +SHEET 3 AA2 3 VAL A 329 CYS A 330 -1 O VAL A 329 N PHE A 315 +SHEET 1 AA3 3 ARG A 352 PRO A 356 0 +SHEET 2 AA3 3 HIS A 413 PHE A 417 -1 O TYR A 414 N VAL A 355 +SHEET 3 AA3 3 LEU A 426 ILE A 427 -1 O ILE A 427 N GLU A 415 +SHEET 1 AA4 2 ILE A 455 LYS A 456 0 +SHEET 2 AA4 2 ILE A 522 VAL A 523 1 O VAL A 523 N ILE A 455 +SHEET 1 AA5 5 ILE C 234 MET C 239 0 +SHEET 2 AA5 5 LEU C 248 PHE C 252 -1 O ILE C 249 N GLY C 238 +SHEET 3 AA5 5 GLN C 257 PRO C 262 -1 O ALA C 258 N MET C 250 +SHEET 4 AA5 5 GLY C 362 ALA C 366 -1 O ALA C 365 N LEU C 259 +SHEET 5 AA5 5 VAL C 305 ARG C 308 -1 N ALA C 306 O LEU C 364 +SHEET 1 AA6 3 PHE C 330 VAL C 331 0 +SHEET 2 AA6 3 ILE C 337 PHE C 339 -1 O CYS C 338 N PHE C 330 +SHEET 3 AA6 3 LEU C 353 CYS C 354 -1 O LEU C 353 N PHE C 339 +SHEET 1 AA7 2 THR C 378 ARG C 380 0 +SHEET 2 AA7 2 HIS C 437 GLU C 439 -1 O TYR C 438 N TRP C 379 +SHEET 1 AA8 2 VAL C 479 LYS C 480 0 +SHEET 2 AA8 2 VAL C 546 GLU C 547 1 O GLU C 547 N VAL C 479 +SHEET 1 AA9 5 THR B 193 ASP B 197 0 +SHEET 2 AA9 5 LEU B 224 PHE B 228 -1 O ARG B 227 N ILE B 194 +SHEET 3 AA9 5 LYS B 233 PRO B 238 -1 O PHE B 236 N LEU B 224 +SHEET 4 AA9 5 LEU B 335 ALA B 342 -1 O SER B 341 N MET B 235 +SHEET 5 AA9 5 THR B 281 ASN B 287 -1 N VAL B 286 O LEU B 336 +SHEET 1 AB1 3 PHE B 306 VAL B 307 0 +SHEET 2 AB1 3 VAL B 313 PHE B 315 -1 O CYS B 314 N PHE B 306 +SHEET 3 AB1 3 VAL B 329 CYS B 330 -1 O VAL B 329 N PHE B 315 +SHEET 1 AB2 3 ARG B 352 PRO B 356 0 +SHEET 2 AB2 3 HIS B 413 PHE B 417 -1 O TYR B 414 N VAL B 355 +SHEET 3 AB2 3 LEU B 426 ILE B 427 -1 O ILE B 427 N GLU B 415 +SHEET 1 AB3 2 ILE B 455 LYS B 456 0 +SHEET 2 AB3 2 ILE B 522 VAL B 523 1 O VAL B 523 N ILE B 455 +SHEET 1 AB4 5 ILE D 234 MET D 239 0 +SHEET 2 AB4 5 LEU D 248 PHE D 252 -1 O ILE D 249 N GLY D 238 +SHEET 3 AB4 5 GLN D 257 PRO D 262 -1 O PHE D 260 N LEU D 248 +SHEET 4 AB4 5 GLY D 362 ALA D 366 -1 O ALA D 365 N LEU D 259 +SHEET 5 AB4 5 VAL D 305 ARG D 308 -1 N ALA D 306 O LEU D 364 +SHEET 1 AB5 3 PHE D 330 VAL D 331 0 +SHEET 2 AB5 3 ILE D 337 PHE D 339 -1 O CYS D 338 N PHE D 330 +SHEET 3 AB5 3 LEU D 353 CYS D 354 -1 O LEU D 353 N PHE D 339 +SHEET 1 AB6 2 THR D 378 ARG D 380 0 +SHEET 2 AB6 2 HIS D 437 GLU D 439 -1 O TYR D 438 N TRP D 379 +SHEET 1 AB7 2 VAL D 479 LYS D 480 0 +SHEET 2 AB7 2 VAL D 546 GLU D 547 1 O GLU D 547 N VAL D 479 +SSBOND 1 CYS A 209 CYS A 319 1555 1555 2.04 +SSBOND 2 CYS A 211 CYS A 323 1555 1555 2.04 +SSBOND 3 CYS A 314 CYS A 330 1555 1555 2.03 +SSBOND 4 CYS A 378 CYS A 452 1555 1555 2.03 +SSBOND 5 CYS A 453 CYS A 512 1555 1555 2.04 +SSBOND 6 CYS C 338 CYS C 354 1555 1555 2.03 +SSBOND 7 CYS C 343 CYS C 347 1555 1555 2.03 +SSBOND 8 CYS C 402 CYS C 476 1555 1555 2.03 +SSBOND 9 CYS C 477 CYS C 536 1555 1555 2.02 +SSBOND 10 CYS B 209 CYS B 319 1555 1555 2.04 +SSBOND 11 CYS B 211 CYS B 323 1555 1555 2.04 +SSBOND 12 CYS B 314 CYS B 330 1555 1555 2.03 +SSBOND 13 CYS B 378 CYS B 452 1555 1555 2.04 +SSBOND 14 CYS B 453 CYS B 512 1555 1555 2.03 +SSBOND 15 CYS D 338 CYS D 354 1555 1555 2.03 +SSBOND 16 CYS D 343 CYS D 347 1555 1555 2.03 +SSBOND 17 CYS D 402 CYS D 476 1555 1555 2.03 +SSBOND 18 CYS D 477 CYS D 536 1555 1555 2.02 +CISPEP 1 GLU A 106 PRO A 107 0 -3.63 +CISPEP 2 GLY A 207 ALA A 208 0 -5.09 +CISPEP 3 LYS A 332 PRO A 333 0 -7.68 +CISPEP 4 TYR A 385 PRO A 386 0 1.19 +CISPEP 5 SER A 487 PRO A 488 0 1.76 +CISPEP 6 LYS C 356 PRO C 357 0 -4.96 +CISPEP 7 GLY C 414 THR C 415 0 -3.41 +CISPEP 8 VAL C 511 PRO C 512 0 -1.77 +CISPEP 9 GLU B 106 PRO B 107 0 -4.25 +CISPEP 10 GLY B 207 ALA B 208 0 -4.68 +CISPEP 11 LYS B 332 PRO B 333 0 -7.18 +CISPEP 12 TYR B 385 PRO B 386 0 1.49 +CISPEP 13 SER B 487 PRO B 488 0 0.98 +CISPEP 14 LYS D 356 PRO D 357 0 -4.39 +CISPEP 15 GLY D 414 THR D 415 0 -4.05 +CISPEP 16 VAL D 511 PRO D 512 0 -1.90 +SITE 1 AC1 16 TYR A 125 LYS A 129 GLN A 200 LYS A 233 +SITE 2 AC1 16 MET A 235 PRO A 279 SER A 341 ALA A 342 +SITE 3 AC1 16 PHE A 343 LEU A 344 SER A 346 LEU A 347 +SITE 4 AC1 16 ASN A 348 ARG A 352 ASP A 430 LYS D 170 +SITE 1 AC2 13 TYR B 125 LYS B 129 LYS B 233 PRO B 279 +SITE 2 AC2 13 SER B 341 ALA B 342 PHE B 343 LEU B 344 +SITE 3 AC2 13 SER B 346 LEU B 347 ASN B 348 ARG B 352 +SITE 4 AC2 13 LYS C 170 +CRYST1 110.059 110.059 461.698 90.00 90.00 90.00 P 41 21 2 16 +ORIGX1 1.000000 0.000000 0.000000 0.00000 +ORIGX2 0.000000 1.000000 0.000000 0.00000 +ORIGX3 0.000000 0.000000 1.000000 0.00000 +SCALE1 0.009086 0.000000 0.000000 0.00000 +SCALE2 0.000000 0.009086 0.000000 0.00000 +SCALE3 0.000000 0.000000 0.002166 0.00000 +ATOM 1 N SER A 89 -50.080 17.388 -22.113 1.00 69.45 N +ATOM 2 CA SER A 89 -49.351 16.577 -23.081 1.00 68.09 C +ATOM 3 C SER A 89 -50.270 15.578 -23.790 1.00 71.23 C +ATOM 4 O SER A 89 -51.412 15.362 -23.369 1.00 66.77 O +ATOM 5 CB SER A 89 -48.200 15.834 -22.397 1.00 60.76 C +ATOM 6 OG SER A 89 -47.294 16.738 -21.791 1.00 60.76 O +ATOM 7 N SER A 90 -49.768 15.001 -24.886 1.00 74.47 N +ATOM 8 CA SER A 90 -50.488 13.988 -25.654 1.00 70.57 C +ATOM 9 C SER A 90 -51.820 14.505 -26.177 1.00 65.72 C +ATOM 10 O SER A 90 -52.858 14.329 -25.528 1.00 58.64 O +ATOM 11 CB SER A 90 -50.721 12.725 -24.820 1.00 64.97 C +ATOM 12 OG SER A 90 -51.550 11.811 -25.518 1.00 56.14 O +ATOM 13 N LYS A 91 -51.801 15.141 -27.352 1.00 65.14 N +ATOM 14 CA LYS A 91 -53.048 15.588 -27.957 1.00 58.33 C +ATOM 15 C LYS A 91 -53.914 14.419 -28.403 1.00 50.96 C +ATOM 16 O LYS A 91 -55.133 14.577 -28.523 1.00 45.72 O +ATOM 17 CB LYS A 91 -52.767 16.506 -29.148 1.00 49.49 C +ATOM 18 CG LYS A 91 -52.050 17.789 -28.789 1.00 52.35 C +ATOM 19 CD LYS A 91 -51.806 18.648 -30.019 1.00 50.79 C +ATOM 20 CE LYS A 91 -50.808 19.757 -29.733 1.00 51.10 C +ATOM 21 NZ LYS A 91 -51.303 21.056 -30.271 1.00 59.36 N +ATOM 22 N LEU A 92 -53.320 13.244 -28.619 1.00 52.59 N +ATOM 23 CA LEU A 92 -54.109 12.101 -29.061 1.00 54.16 C +ATOM 24 C LEU A 92 -55.051 11.637 -27.956 1.00 53.23 C +ATOM 25 O LEU A 92 -56.246 11.425 -28.199 1.00 49.37 O +ATOM 26 CB LEU A 92 -53.183 10.967 -29.520 1.00 46.72 C +ATOM 27 CG LEU A 92 -53.723 9.889 -30.474 1.00 39.69 C +ATOM 28 CD1 LEU A 92 -54.374 8.755 -29.719 1.00 48.43 C +ATOM 29 CD2 LEU A 92 -54.710 10.465 -31.462 1.00 38.00 C +ATOM 30 N GLN A 93 -54.539 11.521 -26.723 1.00 52.43 N +ATOM 31 CA GLN A 93 -55.379 11.096 -25.604 1.00 50.58 C +ATOM 32 C GLN A 93 -56.489 12.096 -25.326 1.00 47.74 C +ATOM 33 O GLN A 93 -57.610 11.706 -24.978 1.00 44.00 O +ATOM 34 CB GLN A 93 -54.533 10.887 -24.353 1.00 45.16 C +ATOM 35 CG GLN A 93 -53.619 9.694 -24.443 1.00 51.45 C +ATOM 36 CD GLN A 93 -52.877 9.421 -23.153 1.00 59.38 C +ATOM 37 OE1 GLN A 93 -53.076 10.107 -22.145 1.00 60.26 O +ATOM 38 NE2 GLN A 93 -52.016 8.408 -23.175 1.00 52.88 N +ATOM 39 N ALA A 94 -56.199 13.389 -25.472 1.00 47.63 N +ATOM 40 CA ALA A 94 -57.234 14.392 -25.265 1.00 46.64 C +ATOM 41 C ALA A 94 -58.347 14.261 -26.295 1.00 45.67 C +ATOM 42 O ALA A 94 -59.513 14.529 -25.981 1.00 45.43 O +ATOM 43 CB ALA A 94 -56.627 15.794 -25.308 1.00 45.28 C +ATOM 44 N LEU A 95 -58.017 13.824 -27.516 1.00 40.15 N +ATOM 45 CA LEU A 95 -59.033 13.727 -28.560 1.00 40.12 C +ATOM 46 C LEU A 95 -60.082 12.685 -28.210 1.00 44.07 C +ATOM 47 O LEU A 95 -61.285 12.965 -28.244 1.00 47.72 O +ATOM 48 CB LEU A 95 -58.397 13.406 -29.915 1.00 42.16 C +ATOM 49 CG LEU A 95 -59.382 13.437 -31.095 1.00 38.00 C +ATOM 50 CD1 LEU A 95 -60.050 14.774 -31.171 1.00 38.00 C +ATOM 51 CD2 LEU A 95 -58.697 13.149 -32.416 1.00 38.00 C +ATOM 52 N PHE A 96 -59.650 11.475 -27.870 1.00 43.71 N +ATOM 53 CA PHE A 96 -60.619 10.421 -27.618 1.00 46.56 C +ATOM 54 C PHE A 96 -61.295 10.562 -26.263 1.00 43.27 C +ATOM 55 O PHE A 96 -62.347 9.952 -26.048 1.00 48.90 O +ATOM 56 CB PHE A 96 -59.946 9.055 -27.760 1.00 51.04 C +ATOM 57 CG PHE A 96 -59.502 8.747 -29.170 1.00 56.37 C +ATOM 58 CD1 PHE A 96 -60.428 8.369 -30.134 1.00 48.00 C +ATOM 59 CD2 PHE A 96 -58.166 8.844 -29.534 1.00 51.88 C +ATOM 60 CE1 PHE A 96 -60.031 8.091 -31.426 1.00 43.76 C +ATOM 61 CE2 PHE A 96 -57.763 8.564 -30.830 1.00 43.47 C +ATOM 62 CZ PHE A 96 -58.698 8.187 -31.774 1.00 44.64 C +ATOM 63 N ALA A 97 -60.744 11.373 -25.364 1.00 38.99 N +ATOM 64 CA ALA A 97 -61.384 11.672 -24.091 1.00 40.19 C +ATOM 65 C ALA A 97 -62.299 12.888 -24.170 1.00 40.83 C +ATOM 66 O ALA A 97 -62.807 13.340 -23.139 1.00 38.33 O +ATOM 67 CB ALA A 97 -60.328 11.881 -23.005 1.00 45.41 C +ATOM 68 N HIS A 98 -62.515 13.418 -25.353 1.00 39.35 N +ATOM 69 CA HIS A 98 -63.402 14.548 -25.539 1.00 40.46 C +ATOM 70 C HIS A 98 -64.853 14.078 -25.503 1.00 40.76 C +ATOM 71 O HIS A 98 -65.151 12.953 -25.906 1.00 44.67 O +ATOM 72 CB HIS A 98 -63.108 15.222 -26.876 1.00 45.49 C +ATOM 73 CG HIS A 98 -63.755 16.561 -27.043 1.00 45.74 C +ATOM 74 ND1 HIS A 98 -65.049 16.710 -27.493 1.00 39.79 N +ATOM 75 CD2 HIS A 98 -63.275 17.812 -26.850 1.00 45.30 C +ATOM 76 CE1 HIS A 98 -65.346 17.996 -27.549 1.00 41.06 C +ATOM 77 NE2 HIS A 98 -64.287 18.685 -27.164 1.00 48.52 N +ATOM 78 N PRO A 99 -65.768 14.913 -25.006 1.00 41.12 N +ATOM 79 CA PRO A 99 -67.188 14.524 -24.983 1.00 43.92 C +ATOM 80 C PRO A 99 -67.725 14.088 -26.332 1.00 49.69 C +ATOM 81 O PRO A 99 -68.725 13.363 -26.383 1.00 50.43 O +ATOM 82 CB PRO A 99 -67.890 15.801 -24.505 1.00 46.05 C +ATOM 83 CG PRO A 99 -66.879 16.488 -23.682 1.00 50.74 C +ATOM 84 CD PRO A 99 -65.539 16.188 -24.308 1.00 48.48 C +ATOM 85 N LEU A 100 -67.127 14.557 -27.430 1.00 46.92 N +ATOM 86 CA LEU A 100 -67.583 14.149 -28.754 1.00 51.50 C +ATOM 87 C LEU A 100 -67.324 12.667 -28.998 1.00 52.64 C +ATOM 88 O LEU A 100 -68.184 11.957 -29.534 1.00 59.97 O +ATOM 89 CB LEU A 100 -66.916 14.999 -29.833 1.00 53.41 C +ATOM 90 CG LEU A 100 -67.877 15.877 -30.633 1.00 48.66 C +ATOM 91 CD1 LEU A 100 -67.111 16.662 -31.683 1.00 44.28 C +ATOM 92 CD2 LEU A 100 -68.983 15.034 -31.268 1.00 42.00 C +ATOM 93 N TYR A 101 -66.134 12.188 -28.640 1.00 45.87 N +ATOM 94 CA TYR A 101 -65.774 10.790 -28.853 1.00 48.87 C +ATOM 95 C TYR A 101 -66.272 9.887 -27.727 1.00 52.48 C +ATOM 96 O TYR A 101 -65.628 8.882 -27.405 1.00 48.53 O +ATOM 97 CB TYR A 101 -64.258 10.661 -29.005 1.00 44.37 C +ATOM 98 CG TYR A 101 -63.712 11.325 -30.247 1.00 45.79 C +ATOM 99 CD1 TYR A 101 -63.608 12.705 -30.343 1.00 44.15 C +ATOM 100 CD2 TYR A 101 -63.286 10.563 -31.323 1.00 48.82 C +ATOM 101 CE1 TYR A 101 -63.108 13.304 -31.486 1.00 45.11 C +ATOM 102 CE2 TYR A 101 -62.782 11.150 -32.462 1.00 45.56 C +ATOM 103 CZ TYR A 101 -62.693 12.518 -32.542 1.00 41.92 C +ATOM 104 OH TYR A 101 -62.191 13.088 -33.690 1.00 38.00 O +ATOM 105 N ASN A 102 -67.432 10.219 -27.147 1.00 51.44 N +ATOM 106 CA ASN A 102 -67.961 9.485 -26.001 1.00 48.87 C +ATOM 107 C ASN A 102 -69.485 9.487 -25.967 1.00 52.22 C +ATOM 108 O ASN A 102 -70.095 8.658 -25.282 1.00 53.16 O +ATOM 109 CB ASN A 102 -67.428 10.081 -24.702 1.00 43.16 C +ATOM 110 CG ASN A 102 -66.012 9.664 -24.417 1.00 44.58 C +ATOM 111 OD1 ASN A 102 -65.662 8.489 -24.547 1.00 50.15 O +ATOM 112 ND2 ASN A 102 -65.179 10.625 -24.041 1.00 44.72 N +ATOM 113 N VAL A 103 -70.106 10.434 -26.659 1.00 53.17 N +ATOM 114 CA VAL A 103 -71.572 10.469 -26.693 1.00 59.33 C +ATOM 115 C VAL A 103 -72.080 9.235 -27.426 1.00 61.62 C +ATOM 116 O VAL A 103 -71.441 8.794 -28.397 1.00 68.04 O +ATOM 117 CB VAL A 103 -72.063 11.751 -27.368 1.00 55.92 C +ATOM 118 CG1 VAL A 103 -71.854 12.951 -26.450 1.00 64.85 C +ATOM 119 CG2 VAL A 103 -71.344 11.955 -28.684 1.00 48.69 C +ATOM 120 N PRO A 104 -73.190 8.636 -26.998 1.00 62.12 N +ATOM 121 CA PRO A 104 -73.728 7.476 -27.721 1.00 70.65 C +ATOM 122 C PRO A 104 -74.178 7.841 -29.132 1.00 85.13 C +ATOM 123 O PRO A 104 -74.672 8.942 -29.390 1.00 84.66 O +ATOM 124 CB PRO A 104 -74.912 7.033 -26.851 1.00 70.44 C +ATOM 125 CG PRO A 104 -74.625 7.609 -25.494 1.00 68.68 C +ATOM 126 CD PRO A 104 -73.914 8.900 -25.745 1.00 61.41 C +ATOM 127 N GLU A 105 -74.028 6.881 -30.044 1.00 86.85 N +ATOM 128 CA GLU A 105 -74.381 7.071 -31.446 1.00 71.98 C +ATOM 129 C GLU A 105 -75.826 6.658 -31.665 1.00 76.27 C +ATOM 130 O GLU A 105 -76.253 5.595 -31.202 1.00 84.62 O +ATOM 131 CB GLU A 105 -73.466 6.251 -32.358 1.00 70.10 C +ATOM 132 CG GLU A 105 -72.267 6.998 -32.916 1.00 73.16 C +ATOM 133 CD GLU A 105 -71.322 6.083 -33.678 1.00 65.73 C +ATOM 134 OE1 GLU A 105 -70.974 5.012 -33.135 1.00 67.29 O +ATOM 135 OE2 GLU A 105 -70.929 6.432 -34.815 1.00 56.61 O +ATOM 136 N GLU A 106 -76.566 7.490 -32.362 1.00 84.85 N +ATOM 137 CA GLU A 106 -77.963 7.187 -32.609 1.00 93.04 C +ATOM 138 C GLU A 106 -78.175 6.794 -34.067 1.00 95.40 C +ATOM 139 O GLU A 106 -77.509 7.338 -34.956 1.00 98.77 O +ATOM 140 CB GLU A 106 -78.853 8.385 -32.259 1.00 96.92 C +ATOM 141 CG GLU A 106 -78.521 8.996 -30.904 1.00 96.11 C +ATOM 142 CD GLU A 106 -78.931 8.110 -29.739 1.00 92.77 C +ATOM 143 OE1 GLU A 106 -79.662 7.121 -29.962 1.00 89.74 O +ATOM 144 OE2 GLU A 106 -78.507 8.396 -28.599 1.00 92.12 O +ATOM 145 N PRO A 107 -79.086 5.848 -34.351 1.00 91.33 N +ATOM 146 CA PRO A 107 -79.866 5.083 -33.371 1.00 86.80 C +ATOM 147 C PRO A 107 -79.039 3.998 -32.692 1.00 86.31 C +ATOM 148 O PRO A 107 -78.074 3.517 -33.286 1.00 83.88 O +ATOM 149 CB PRO A 107 -80.980 4.451 -34.221 1.00 93.35 C +ATOM 150 CG PRO A 107 -80.973 5.211 -35.513 1.00 98.31 C +ATOM 151 CD PRO A 107 -79.544 5.587 -35.723 1.00 93.88 C +ATOM 152 N PRO A 108 -79.430 3.598 -31.484 1.00 87.58 N +ATOM 153 CA PRO A 108 -78.714 2.518 -30.793 1.00 88.98 C +ATOM 154 C PRO A 108 -78.944 1.178 -31.480 1.00 95.70 C +ATOM 155 O PRO A 108 -79.831 1.013 -32.321 1.00100.27 O +ATOM 156 CB PRO A 108 -79.299 2.530 -29.377 1.00 74.95 C +ATOM 157 CG PRO A 108 -80.121 3.788 -29.280 1.00 73.50 C +ATOM 158 CD PRO A 108 -80.515 4.164 -30.668 1.00 78.06 C +ATOM 159 N LEU A 109 -78.117 0.205 -31.105 1.00 90.31 N +ATOM 160 CA LEU A 109 -78.110 -1.105 -31.745 1.00 90.40 C +ATOM 161 C LEU A 109 -78.939 -2.084 -30.924 1.00 97.39 C +ATOM 162 O LEU A 109 -78.658 -2.302 -29.741 1.00 96.31 O +ATOM 163 CB LEU A 109 -76.681 -1.626 -31.906 1.00 79.04 C +ATOM 164 CG LEU A 109 -75.643 -0.656 -32.471 1.00 73.46 C +ATOM 165 CD1 LEU A 109 -74.252 -1.252 -32.366 1.00 56.89 C +ATOM 166 CD2 LEU A 109 -75.974 -0.314 -33.911 1.00 79.24 C +ATOM 167 N LEU A 110 -79.966 -2.666 -31.552 1.00104.65 N +ATOM 168 CA LEU A 110 -80.746 -3.704 -30.889 1.00102.24 C +ATOM 169 C LEU A 110 -79.993 -5.026 -30.829 1.00 96.60 C +ATOM 170 O LEU A 110 -80.301 -5.862 -29.973 1.00 92.57 O +ATOM 171 CB LEU A 110 -82.099 -3.898 -31.584 1.00 96.49 C +ATOM 172 CG LEU A 110 -82.327 -3.352 -32.996 1.00105.11 C +ATOM 173 CD1 LEU A 110 -83.325 -4.224 -33.755 1.00107.86 C +ATOM 174 CD2 LEU A 110 -82.821 -1.909 -32.944 1.00102.89 C +ATOM 175 N GLY A 111 -79.016 -5.231 -31.711 1.00 91.19 N +ATOM 176 CA GLY A 111 -78.296 -6.485 -31.769 1.00 98.71 C +ATOM 177 C GLY A 111 -78.877 -7.435 -32.794 1.00104.44 C +ATOM 178 O GLY A 111 -79.901 -7.177 -33.436 1.00103.41 O +ATOM 179 N ALA A 112 -78.185 -8.564 -32.955 1.00101.90 N +ATOM 180 CA ALA A 112 -78.594 -9.613 -33.883 1.00101.99 C +ATOM 181 C ALA A 112 -78.729 -9.082 -35.308 1.00105.42 C +ATOM 182 O ALA A 112 -77.913 -9.413 -36.174 1.00109.31 O +ATOM 183 CB ALA A 112 -79.905 -10.255 -33.416 1.00 98.35 C +ATOM 184 N GLU A 113 -79.739 -8.244 -35.561 1.00101.98 N +ATOM 185 CA GLU A 113 -79.957 -7.711 -36.899 1.00 97.28 C +ATOM 186 C GLU A 113 -79.072 -6.513 -37.208 1.00 96.01 C +ATOM 187 O GLU A 113 -79.061 -6.051 -38.354 1.00 94.07 O +ATOM 188 CB GLU A 113 -81.427 -7.313 -37.090 1.00 92.82 C +ATOM 189 CG GLU A 113 -82.434 -8.409 -36.765 1.00103.32 C +ATOM 190 CD GLU A 113 -82.760 -8.491 -35.284 1.00112.47 C +ATOM 191 OE1 GLU A 113 -82.583 -7.476 -34.576 1.00110.55 O +ATOM 192 OE2 GLU A 113 -83.196 -9.571 -34.829 1.00106.98 O +ATOM 193 N ASP A 114 -78.308 -6.020 -36.235 1.00 93.45 N +ATOM 194 CA ASP A 114 -77.398 -4.904 -36.451 1.00 85.85 C +ATOM 195 C ASP A 114 -75.939 -5.343 -36.445 1.00 76.49 C +ATOM 196 O ASP A 114 -75.045 -4.494 -36.512 1.00 73.93 O +ATOM 197 CB ASP A 114 -77.637 -3.822 -35.393 1.00 88.87 C +ATOM 198 CG ASP A 114 -78.980 -3.120 -35.560 1.00 85.26 C +ATOM 199 OD1 ASP A 114 -79.685 -3.400 -36.552 1.00 82.36 O +ATOM 200 OD2 ASP A 114 -79.340 -2.298 -34.687 1.00 86.07 O +ATOM 201 N SER A 115 -75.682 -6.649 -36.400 1.00 72.24 N +ATOM 202 CA SER A 115 -74.342 -7.217 -36.539 1.00 75.41 C +ATOM 203 C SER A 115 -74.359 -8.078 -37.794 1.00 76.04 C +ATOM 204 O SER A 115 -75.092 -9.070 -37.856 1.00 83.27 O +ATOM 205 CB SER A 115 -73.940 -8.039 -35.312 1.00 76.92 C +ATOM 206 OG SER A 115 -73.428 -7.222 -34.273 1.00 69.35 O +ATOM 207 N LEU A 116 -73.588 -7.678 -38.810 1.00 68.67 N +ATOM 208 CA LEU A 116 -73.691 -8.337 -40.109 1.00 64.93 C +ATOM 209 C LEU A 116 -73.308 -9.810 -40.055 1.00 65.30 C +ATOM 210 O LEU A 116 -73.712 -10.572 -40.940 1.00 71.04 O +ATOM 211 CB LEU A 116 -72.850 -7.604 -41.158 1.00 62.82 C +ATOM 212 CG LEU A 116 -71.341 -7.394 -41.022 1.00 62.35 C +ATOM 213 CD1 LEU A 116 -70.544 -8.658 -41.298 1.00 59.98 C +ATOM 214 CD2 LEU A 116 -70.914 -6.298 -41.973 1.00 60.11 C +ATOM 215 N LEU A 117 -72.535 -10.228 -39.059 1.00 65.20 N +ATOM 216 CA LEU A 117 -72.116 -11.617 -38.934 1.00 66.13 C +ATOM 217 C LEU A 117 -72.902 -12.291 -37.814 1.00 75.65 C +ATOM 218 O LEU A 117 -72.884 -11.825 -36.669 1.00 79.71 O +ATOM 219 CB LEU A 117 -70.612 -11.700 -38.669 1.00 58.78 C +ATOM 220 CG LEU A 117 -69.857 -12.670 -39.578 1.00 55.22 C +ATOM 221 CD1 LEU A 117 -70.019 -12.263 -41.031 1.00 56.44 C +ATOM 222 CD2 LEU A 117 -68.389 -12.753 -39.201 1.00 50.02 C +ATOM 223 N ALA A 118 -73.590 -13.384 -38.145 1.00 75.45 N +ATOM 224 CA ALA A 118 -74.263 -14.193 -37.136 1.00 74.90 C +ATOM 225 C ALA A 118 -73.253 -15.108 -36.451 1.00 75.36 C +ATOM 226 O ALA A 118 -72.476 -15.799 -37.116 1.00 70.64 O +ATOM 227 CB ALA A 118 -75.389 -15.016 -37.762 1.00 75.86 C +ATOM 228 N SER A 119 -73.277 -15.111 -35.116 1.00 81.64 N +ATOM 229 CA SER A 119 -72.243 -15.781 -34.330 1.00 77.24 C +ATOM 230 C SER A 119 -72.185 -17.278 -34.627 1.00 76.83 C +ATOM 231 O SER A 119 -71.121 -17.822 -34.938 1.00 68.36 O +ATOM 232 CB SER A 119 -72.480 -15.525 -32.837 1.00 76.74 C +ATOM 233 OG SER A 119 -73.839 -15.727 -32.478 1.00 78.07 O +ATOM 234 N GLN A 120 -73.319 -17.971 -34.495 1.00 85.88 N +ATOM 235 CA GLN A 120 -73.312 -19.424 -34.646 1.00 86.56 C +ATOM 236 C GLN A 120 -72.981 -19.840 -36.077 1.00 85.74 C +ATOM 237 O GLN A 120 -72.226 -20.797 -36.292 1.00 79.26 O +ATOM 238 CB GLN A 120 -74.666 -19.999 -34.223 1.00 94.83 C +ATOM 239 CG GLN A 120 -74.660 -21.505 -33.988 1.00 92.72 C +ATOM 240 CD GLN A 120 -76.055 -22.092 -33.865 1.00 92.83 C +ATOM 241 OE1 GLN A 120 -76.795 -22.188 -34.848 1.00 85.40 O +ATOM 242 NE2 GLN A 120 -76.424 -22.481 -32.649 1.00 93.97 N +ATOM 243 N GLU A 121 -73.509 -19.117 -37.067 1.00 84.96 N +ATOM 244 CA GLU A 121 -73.269 -19.492 -38.456 1.00 76.25 C +ATOM 245 C GLU A 121 -71.836 -19.198 -38.875 1.00 70.74 C +ATOM 246 O GLU A 121 -71.211 -20.009 -39.567 1.00 71.82 O +ATOM 247 CB GLU A 121 -74.250 -18.769 -39.373 1.00 77.07 C +ATOM 248 CG GLU A 121 -74.004 -19.037 -40.845 1.00 77.78 C +ATOM 249 CD GLU A 121 -74.713 -18.044 -41.738 1.00 97.71 C +ATOM 250 OE1 GLU A 121 -75.373 -17.131 -41.197 1.00101.52 O +ATOM 251 OE2 GLU A 121 -74.608 -18.174 -42.978 1.00104.72 O +ATOM 252 N ALA A 122 -71.298 -18.045 -38.468 1.00 71.15 N +ATOM 253 CA ALA A 122 -69.951 -17.670 -38.889 1.00 73.83 C +ATOM 254 C ALA A 122 -68.901 -18.614 -38.315 1.00 72.34 C +ATOM 255 O ALA A 122 -67.979 -19.031 -39.026 1.00 67.25 O +ATOM 256 CB ALA A 122 -69.649 -16.230 -38.477 1.00 71.20 C +ATOM 257 N LEU A 123 -69.023 -18.962 -37.030 1.00 72.15 N +ATOM 258 CA LEU A 123 -68.045 -19.853 -36.415 1.00 66.33 C +ATOM 259 C LEU A 123 -68.030 -21.218 -37.092 1.00 67.84 C +ATOM 260 O LEU A 123 -66.969 -21.845 -37.197 1.00 62.14 O +ATOM 261 CB LEU A 123 -68.321 -19.988 -34.917 1.00 63.38 C +ATOM 262 CG LEU A 123 -67.620 -18.992 -33.979 1.00 56.74 C +ATOM 263 CD1 LEU A 123 -66.119 -18.941 -34.236 1.00 55.12 C +ATOM 264 CD2 LEU A 123 -68.221 -17.601 -34.067 1.00 53.12 C +ATOM 265 N ARG A 124 -69.185 -21.686 -37.575 1.00 71.92 N +ATOM 266 CA ARG A 124 -69.227 -22.960 -38.287 1.00 75.29 C +ATOM 267 C ARG A 124 -68.477 -22.870 -39.612 1.00 72.69 C +ATOM 268 O ARG A 124 -67.684 -23.758 -39.948 1.00 68.78 O +ATOM 269 CB ARG A 124 -70.679 -23.386 -38.524 1.00 75.01 C +ATOM 270 CG ARG A 124 -70.837 -24.798 -39.077 1.00 66.79 C +ATOM 271 CD ARG A 124 -72.281 -25.095 -39.466 1.00 74.94 C +ATOM 272 NE ARG A 124 -73.240 -24.695 -38.435 1.00 90.58 N +ATOM 273 CZ ARG A 124 -74.115 -23.699 -38.559 1.00 91.91 C +ATOM 274 NH1 ARG A 124 -74.172 -22.991 -39.680 1.00 89.21 N +ATOM 275 NH2 ARG A 124 -74.943 -23.414 -37.560 1.00 86.65 N +ATOM 276 N TYR A 125 -68.720 -21.800 -40.378 1.00 69.59 N +ATOM 277 CA TYR A 125 -68.075 -21.635 -41.679 1.00 64.55 C +ATOM 278 C TYR A 125 -66.563 -21.506 -41.543 1.00 68.07 C +ATOM 279 O TYR A 125 -65.809 -22.111 -42.314 1.00 67.64 O +ATOM 280 CB TYR A 125 -68.651 -20.417 -42.397 1.00 66.66 C +ATOM 281 CG TYR A 125 -68.034 -20.160 -43.755 1.00 77.33 C +ATOM 282 CD1 TYR A 125 -68.047 -21.133 -44.747 1.00 76.60 C +ATOM 283 CD2 TYR A 125 -67.419 -18.948 -44.037 1.00 78.48 C +ATOM 284 CE1 TYR A 125 -67.479 -20.895 -45.985 1.00 73.59 C +ATOM 285 CE2 TYR A 125 -66.850 -18.702 -45.270 1.00 75.38 C +ATOM 286 CZ TYR A 125 -66.882 -19.678 -46.238 1.00 78.80 C +ATOM 287 OH TYR A 125 -66.316 -19.431 -47.465 1.00 88.41 O +ATOM 288 N TYR A 126 -66.098 -20.677 -40.601 1.00 69.21 N +ATOM 289 CA TYR A 126 -64.658 -20.561 -40.383 1.00 66.43 C +ATOM 290 C TYR A 126 -64.074 -21.865 -39.856 1.00 61.54 C +ATOM 291 O TYR A 126 -62.899 -22.161 -40.101 1.00 54.81 O +ATOM 292 CB TYR A 126 -64.338 -19.402 -39.431 1.00 62.01 C +ATOM 293 CG TYR A 126 -64.523 -18.029 -40.051 1.00 61.84 C +ATOM 294 CD1 TYR A 126 -64.308 -17.826 -41.410 1.00 68.66 C +ATOM 295 CD2 TYR A 126 -64.934 -16.945 -39.288 1.00 60.13 C +ATOM 296 CE1 TYR A 126 -64.487 -16.583 -41.989 1.00 61.52 C +ATOM 297 CE2 TYR A 126 -65.119 -15.694 -39.861 1.00 60.90 C +ATOM 298 CZ TYR A 126 -64.892 -15.522 -41.213 1.00 61.15 C +ATOM 299 OH TYR A 126 -65.068 -14.286 -41.792 1.00 62.64 O +ATOM 300 N ARG A 127 -64.872 -22.653 -39.130 1.00 64.77 N +ATOM 301 CA ARG A 127 -64.384 -23.937 -38.646 1.00 64.56 C +ATOM 302 C ARG A 127 -64.228 -24.942 -39.780 1.00 59.22 C +ATOM 303 O ARG A 127 -63.312 -25.772 -39.746 1.00 57.77 O +ATOM 304 CB ARG A 127 -65.311 -24.473 -37.553 1.00 66.12 C +ATOM 305 CG ARG A 127 -64.709 -25.613 -36.744 1.00 73.52 C +ATOM 306 CD ARG A 127 -65.549 -25.947 -35.521 1.00 76.17 C +ATOM 307 NE ARG A 127 -65.545 -24.869 -34.531 1.00 78.24 N +ATOM 308 CZ ARG A 127 -66.552 -24.023 -34.339 1.00 75.93 C +ATOM 309 NH1 ARG A 127 -67.650 -24.127 -35.077 1.00 77.89 N +ATOM 310 NH2 ARG A 127 -66.463 -23.077 -33.409 1.00 57.73 N +ATOM 311 N ARG A 128 -65.080 -24.867 -40.805 1.00 62.30 N +ATOM 312 CA ARG A 128 -64.911 -25.760 -41.947 1.00 62.71 C +ATOM 313 C ARG A 128 -63.675 -25.385 -42.747 1.00 57.28 C +ATOM 314 O ARG A 128 -62.903 -26.260 -43.153 1.00 56.41 O +ATOM 315 CB ARG A 128 -66.147 -25.727 -42.851 1.00 71.28 C +ATOM 316 CG ARG A 128 -67.347 -26.518 -42.329 1.00 79.17 C +ATOM 317 CD ARG A 128 -68.339 -26.869 -43.449 1.00 83.06 C +ATOM 318 NE ARG A 128 -69.101 -25.721 -43.945 1.00 85.40 N +ATOM 319 CZ ARG A 128 -70.339 -25.410 -43.561 1.00 84.78 C +ATOM 320 NH1 ARG A 128 -70.980 -26.156 -42.666 1.00 84.04 N +ATOM 321 NH2 ARG A 128 -70.944 -24.347 -44.078 1.00 71.80 N +ATOM 322 N LYS A 129 -63.467 -24.086 -42.975 1.00 61.61 N +ATOM 323 CA LYS A 129 -62.293 -23.644 -43.720 1.00 67.05 C +ATOM 324 C LYS A 129 -60.996 -23.966 -42.987 1.00 59.53 C +ATOM 325 O LYS A 129 -59.953 -24.142 -43.626 1.00 58.20 O +ATOM 326 CB LYS A 129 -62.387 -22.149 -44.030 1.00 71.46 C +ATOM 327 CG LYS A 129 -63.408 -21.808 -45.118 1.00 71.08 C +ATOM 328 CD LYS A 129 -62.737 -21.213 -46.363 1.00 80.12 C +ATOM 329 CE LYS A 129 -61.860 -22.239 -47.088 1.00 69.47 C +ATOM 330 NZ LYS A 129 -61.143 -21.687 -48.278 1.00 77.84 N +ATOM 331 N VAL A 130 -61.029 -24.041 -41.656 1.00 58.45 N +ATOM 332 CA VAL A 130 -59.849 -24.500 -40.933 1.00 57.07 C +ATOM 333 C VAL A 130 -59.645 -25.988 -41.171 1.00 57.42 C +ATOM 334 O VAL A 130 -58.515 -26.459 -41.350 1.00 56.46 O +ATOM 335 CB VAL A 130 -59.972 -24.178 -39.434 1.00 54.82 C +ATOM 336 CG1 VAL A 130 -58.868 -24.865 -38.648 1.00 56.40 C +ATOM 337 CG2 VAL A 130 -59.926 -22.684 -39.211 1.00 54.20 C +ATOM 338 N ALA A 131 -60.740 -26.747 -41.204 1.00 60.33 N +ATOM 339 CA ALA A 131 -60.642 -28.168 -41.513 1.00 64.07 C +ATOM 340 C ALA A 131 -60.128 -28.375 -42.931 1.00 68.96 C +ATOM 341 O ALA A 131 -59.212 -29.174 -43.161 1.00 66.96 O +ATOM 342 CB ALA A 131 -62.006 -28.837 -41.330 1.00 59.25 C +ATOM 343 N ARG A 132 -60.684 -27.627 -43.893 1.00 70.81 N +ATOM 344 CA ARG A 132 -60.273 -27.776 -45.286 1.00 62.47 C +ATOM 345 C ARG A 132 -58.837 -27.320 -45.488 1.00 61.86 C +ATOM 346 O ARG A 132 -58.111 -27.887 -46.310 1.00 67.74 O +ATOM 347 CB ARG A 132 -61.221 -27.001 -46.204 1.00 55.66 C +ATOM 348 CG ARG A 132 -62.639 -27.544 -46.209 1.00 70.05 C +ATOM 349 CD ARG A 132 -63.538 -26.871 -47.243 1.00 92.63 C +ATOM 350 NE ARG A 132 -64.908 -27.390 -47.201 1.00107.27 N +ATOM 351 CZ ARG A 132 -65.899 -26.963 -47.981 1.00118.99 C +ATOM 352 NH1 ARG A 132 -65.675 -26.008 -48.876 1.00125.70 N +ATOM 353 NH2 ARG A 132 -67.113 -27.491 -47.868 1.00105.86 N +ATOM 354 N TRP A 133 -58.414 -26.289 -44.760 1.00 60.56 N +ATOM 355 CA TRP A 133 -57.034 -25.846 -44.879 1.00 63.76 C +ATOM 356 C TRP A 133 -56.071 -26.882 -44.315 1.00 64.17 C +ATOM 357 O TRP A 133 -55.022 -27.150 -44.915 1.00 67.42 O +ATOM 358 CB TRP A 133 -56.836 -24.505 -44.178 1.00 59.42 C +ATOM 359 CG TRP A 133 -55.502 -23.898 -44.463 1.00 52.83 C +ATOM 360 CD1 TRP A 133 -55.210 -22.988 -45.435 1.00 57.64 C +ATOM 361 CD2 TRP A 133 -54.270 -24.181 -43.794 1.00 51.51 C +ATOM 362 NE1 TRP A 133 -53.874 -22.672 -45.400 1.00 59.89 N +ATOM 363 CE2 TRP A 133 -53.274 -23.394 -44.402 1.00 54.08 C +ATOM 364 CE3 TRP A 133 -53.914 -25.016 -42.734 1.00 58.55 C +ATOM 365 CZ2 TRP A 133 -51.947 -23.418 -43.986 1.00 50.18 C +ATOM 366 CZ3 TRP A 133 -52.597 -25.040 -42.325 1.00 63.74 C +ATOM 367 CH2 TRP A 133 -51.628 -24.245 -42.949 1.00 53.52 C +ATOM 368 N ASN A 134 -56.409 -27.488 -43.173 1.00 63.05 N +ATOM 369 CA ASN A 134 -55.449 -28.383 -42.531 1.00 71.73 C +ATOM 370 C ASN A 134 -55.058 -29.548 -43.418 1.00 79.79 C +ATOM 371 O ASN A 134 -53.914 -30.012 -43.357 1.00 80.93 O +ATOM 372 CB ASN A 134 -55.979 -28.884 -41.193 1.00 74.55 C +ATOM 373 CG ASN A 134 -55.485 -28.046 -40.056 1.00 73.04 C +ATOM 374 OD1 ASN A 134 -56.233 -27.666 -39.158 1.00 75.57 O +ATOM 375 ND2 ASN A 134 -54.190 -27.743 -40.091 1.00 66.31 N +ATOM 376 N ARG A 135 -55.974 -30.034 -44.243 1.00 80.78 N +ATOM 377 CA ARG A 135 -55.593 -31.057 -45.199 1.00 77.26 C +ATOM 378 C ARG A 135 -54.702 -30.450 -46.278 1.00 76.42 C +ATOM 379 O ARG A 135 -53.482 -30.485 -46.103 1.00 80.00 O +ATOM 380 CB ARG A 135 -56.854 -31.761 -45.701 1.00 73.52 C +ATOM 381 CG ARG A 135 -57.040 -33.100 -44.969 1.00 75.58 C +ATOM 382 CD ARG A 135 -58.472 -33.595 -44.882 1.00 72.06 C +ATOM 383 NE ARG A 135 -59.178 -33.628 -46.150 1.00 72.65 N +ATOM 384 CZ ARG A 135 -60.135 -32.761 -46.442 1.00 74.51 C +ATOM 385 NH1 ARG A 135 -60.456 -31.845 -45.541 1.00 71.48 N +ATOM 386 NH2 ARG A 135 -60.774 -32.811 -47.603 1.00 80.70 N +ATOM 387 N ARG A 136 -55.263 -29.833 -47.329 1.00 77.38 N +ATOM 388 CA ARG A 136 -54.508 -29.359 -48.501 1.00 85.37 C +ATOM 389 C ARG A 136 -52.998 -29.211 -48.295 1.00 92.09 C +ATOM 390 O ARG A 136 -52.198 -29.652 -49.130 1.00 92.61 O +ATOM 391 CB ARG A 136 -55.026 -27.991 -48.956 1.00 77.10 C +ATOM 392 CG ARG A 136 -56.342 -27.964 -49.686 1.00 76.40 C +ATOM 393 CD ARG A 136 -56.452 -26.637 -50.416 1.00 75.29 C +ATOM 394 NE ARG A 136 -56.514 -25.492 -49.511 1.00 84.87 N +ATOM 395 CZ ARG A 136 -57.551 -24.663 -49.448 1.00 94.64 C +ATOM 396 NH1 ARG A 136 -58.595 -24.859 -50.244 1.00 98.16 N +ATOM 397 NH2 ARG A 136 -57.549 -23.638 -48.602 1.00 81.77 N +ATOM 398 N HIS A 137 -52.604 -28.631 -47.154 1.00 86.85 N +ATOM 399 CA HIS A 137 -51.190 -28.472 -46.839 1.00 85.66 C +ATOM 400 C HIS A 137 -50.575 -29.753 -46.286 1.00 88.25 C +ATOM 401 O HIS A 137 -49.399 -30.024 -46.554 1.00 99.78 O +ATOM 402 CB HIS A 137 -50.997 -27.290 -45.888 1.00 78.90 C +ATOM 403 CG HIS A 137 -50.976 -25.964 -46.589 1.00 79.09 C +ATOM 404 ND1 HIS A 137 -50.024 -24.999 -46.337 1.00 74.31 N +ATOM 405 CD2 HIS A 137 -51.774 -25.460 -47.563 1.00 68.61 C +ATOM 406 CE1 HIS A 137 -50.245 -23.954 -47.115 1.00 63.68 C +ATOM 407 NE2 HIS A 137 -51.301 -24.208 -47.868 1.00 64.26 N +ATOM 408 N LYS A 138 -51.326 -30.542 -45.514 1.00 85.18 N +ATOM 409 CA LYS A 138 -50.816 -31.845 -45.088 1.00 87.70 C +ATOM 410 C LYS A 138 -50.508 -32.737 -46.287 1.00100.67 C +ATOM 411 O LYS A 138 -49.467 -33.407 -46.320 1.00104.82 O +ATOM 412 CB LYS A 138 -51.819 -32.532 -44.166 1.00 79.76 C +ATOM 413 CG LYS A 138 -51.557 -34.012 -43.982 1.00 85.33 C +ATOM 414 CD LYS A 138 -52.554 -34.610 -43.021 1.00 94.02 C +ATOM 415 CE LYS A 138 -52.308 -34.101 -41.611 1.00 99.13 C +ATOM 416 NZ LYS A 138 -50.946 -34.455 -41.109 1.00 84.65 N +ATOM 417 N MET A 139 -51.401 -32.767 -47.273 1.00101.02 N +ATOM 418 CA MET A 139 -51.144 -33.484 -48.521 1.00 94.48 C +ATOM 419 C MET A 139 -50.029 -32.805 -49.307 1.00 85.70 C +ATOM 420 O MET A 139 -49.241 -33.469 -49.980 1.00 88.29 O +ATOM 421 CB MET A 139 -52.410 -33.578 -49.377 1.00 94.34 C +ATOM 422 CG MET A 139 -53.511 -34.426 -48.764 1.00107.82 C +ATOM 423 SD MET A 139 -54.805 -34.865 -49.944 1.00154.98 S +ATOM 424 CE MET A 139 -54.042 -36.230 -50.816 1.00 94.08 C +ATOM 425 N ASP A 150 -45.820 -31.093 -35.722 1.00105.34 N +ATOM 426 CA ASP A 150 -46.708 -30.009 -35.313 1.00112.25 C +ATOM 427 C ASP A 150 -48.179 -30.412 -35.437 1.00120.45 C +ATOM 428 O ASP A 150 -48.581 -30.997 -36.448 1.00109.22 O +ATOM 429 CB ASP A 150 -46.437 -28.754 -36.148 1.00115.55 C +ATOM 430 CG ASP A 150 -45.033 -28.211 -35.950 1.00119.31 C +ATOM 431 OD1 ASP A 150 -44.476 -28.388 -34.845 1.00110.75 O +ATOM 432 OD2 ASP A 150 -44.487 -27.607 -36.900 1.00117.37 O +ATOM 433 N PRO A 151 -48.978 -30.092 -34.418 1.00126.31 N +ATOM 434 CA PRO A 151 -50.414 -30.421 -34.456 1.00116.07 C +ATOM 435 C PRO A 151 -51.145 -29.578 -35.488 1.00108.89 C +ATOM 436 O PRO A 151 -50.618 -28.558 -35.960 1.00 96.81 O +ATOM 437 CB PRO A 151 -50.886 -30.097 -33.029 1.00102.67 C +ATOM 438 CG PRO A 151 -49.934 -29.057 -32.548 1.00103.79 C +ATOM 439 CD PRO A 151 -48.604 -29.374 -33.185 1.00113.15 C +ATOM 440 N PRO A 152 -52.367 -29.961 -35.857 1.00108.22 N +ATOM 441 CA PRO A 152 -53.120 -29.186 -36.851 1.00 90.38 C +ATOM 442 C PRO A 152 -53.632 -27.868 -36.287 1.00 80.74 C +ATOM 443 O PRO A 152 -53.572 -27.586 -35.088 1.00 78.18 O +ATOM 444 CB PRO A 152 -54.277 -30.117 -37.229 1.00 89.64 C +ATOM 445 CG PRO A 152 -54.452 -31.002 -36.044 1.00 93.33 C +ATOM 446 CD PRO A 152 -53.072 -31.201 -35.478 1.00102.82 C +ATOM 447 N LEU A 153 -54.137 -27.046 -37.202 1.00 79.52 N +ATOM 448 CA LEU A 153 -54.658 -25.736 -36.846 1.00 78.24 C +ATOM 449 C LEU A 153 -55.868 -25.878 -35.928 1.00 71.75 C +ATOM 450 O LEU A 153 -56.635 -26.841 -36.012 1.00 64.95 O +ATOM 451 CB LEU A 153 -55.032 -24.954 -38.110 1.00 71.92 C +ATOM 452 CG LEU A 153 -54.525 -23.517 -38.298 1.00 65.85 C +ATOM 453 CD1 LEU A 153 -54.997 -22.632 -37.156 1.00 69.63 C +ATOM 454 CD2 LEU A 153 -53.004 -23.455 -38.444 1.00 61.49 C +ATOM 455 N GLN A 154 -56.005 -24.924 -35.013 1.00 69.86 N +ATOM 456 CA GLN A 154 -57.145 -24.846 -34.114 1.00 70.51 C +ATOM 457 C GLN A 154 -57.827 -23.500 -34.304 1.00 66.82 C +ATOM 458 O GLN A 154 -57.177 -22.451 -34.227 1.00 63.90 O +ATOM 459 CB GLN A 154 -56.713 -25.039 -32.656 1.00 83.45 C +ATOM 460 CG GLN A 154 -57.871 -25.321 -31.712 1.00 90.64 C +ATOM 461 CD GLN A 154 -58.267 -26.785 -31.708 1.00 97.44 C +ATOM 462 OE1 GLN A 154 -57.796 -27.569 -32.537 1.00100.07 O +ATOM 463 NE2 GLN A 154 -59.155 -27.159 -30.790 1.00 84.16 N +ATOM 464 N LEU A 155 -59.132 -23.532 -34.553 1.00 58.39 N +ATOM 465 CA LEU A 155 -59.916 -22.318 -34.748 1.00 56.56 C +ATOM 466 C LEU A 155 -60.446 -21.867 -33.389 1.00 62.91 C +ATOM 467 O LEU A 155 -61.385 -22.466 -32.854 1.00 63.35 O +ATOM 468 CB LEU A 155 -61.050 -22.578 -35.740 1.00 54.71 C +ATOM 469 CG LEU A 155 -61.876 -21.417 -36.304 1.00 52.16 C +ATOM 470 CD1 LEU A 155 -63.109 -21.145 -35.450 1.00 55.22 C +ATOM 471 CD2 LEU A 155 -61.027 -20.167 -36.449 1.00 51.09 C +ATOM 472 N ARG A 156 -59.846 -20.813 -32.833 1.00 59.48 N +ATOM 473 CA ARG A 156 -60.212 -20.292 -31.521 1.00 61.71 C +ATOM 474 C ARG A 156 -61.043 -19.024 -31.655 1.00 57.96 C +ATOM 475 O ARG A 156 -60.689 -18.125 -32.424 1.00 61.25 O +ATOM 476 CB ARG A 156 -58.966 -19.998 -30.680 1.00 71.80 C +ATOM 477 CG ARG A 156 -58.332 -21.228 -30.048 1.00 92.42 C +ATOM 478 CD ARG A 156 -57.317 -20.843 -28.977 1.00 93.73 C +ATOM 479 NE ARG A 156 -56.117 -20.236 -29.546 1.00102.24 N +ATOM 480 CZ ARG A 156 -55.033 -20.919 -29.904 1.00114.68 C +ATOM 481 NH1 ARG A 156 -54.993 -22.239 -29.754 1.00108.22 N +ATOM 482 NH2 ARG A 156 -53.986 -20.282 -30.412 1.00114.13 N +ATOM 483 N LEU A 157 -62.137 -18.950 -30.889 1.00 53.10 N +ATOM 484 CA LEU A 157 -62.967 -17.747 -30.870 1.00 52.11 C +ATOM 485 C LEU A 157 -62.182 -16.538 -30.378 1.00 59.64 C +ATOM 486 O LEU A 157 -62.484 -15.399 -30.754 1.00 57.20 O +ATOM 487 CB LEU A 157 -64.197 -17.974 -29.990 1.00 50.46 C +ATOM 488 CG LEU A 157 -65.567 -17.482 -30.466 1.00 47.01 C +ATOM 489 CD1 LEU A 157 -66.649 -17.866 -29.469 1.00 38.00 C +ATOM 490 CD2 LEU A 157 -65.575 -15.984 -30.680 1.00 53.76 C +ATOM 491 N GLU A 158 -61.173 -16.764 -29.538 1.00 67.74 N +ATOM 492 CA GLU A 158 -60.361 -15.678 -29.004 1.00 67.85 C +ATOM 493 C GLU A 158 -59.412 -15.082 -30.037 1.00 69.39 C +ATOM 494 O GLU A 158 -58.617 -14.207 -29.677 1.00 79.66 O +ATOM 495 CB GLU A 158 -59.554 -16.163 -27.794 1.00 71.94 C +ATOM 496 CG GLU A 158 -60.345 -16.975 -26.770 1.00 76.16 C +ATOM 497 CD GLU A 158 -60.339 -18.466 -27.059 1.00 74.61 C +ATOM 498 OE1 GLU A 158 -61.358 -18.976 -27.571 1.00 70.21 O +ATOM 499 OE2 GLU A 158 -59.314 -19.126 -26.780 1.00 77.45 O +ATOM 500 N ALA A 159 -59.449 -15.534 -31.289 1.00 62.81 N +ATOM 501 CA ALA A 159 -58.561 -14.982 -32.299 1.00 55.00 C +ATOM 502 C ALA A 159 -58.975 -13.559 -32.652 1.00 51.21 C +ATOM 503 O ALA A 159 -60.147 -13.181 -32.562 1.00 46.16 O +ATOM 504 CB ALA A 159 -58.558 -15.853 -33.553 1.00 52.04 C +ATOM 505 N SER A 160 -57.989 -12.768 -33.071 1.00 47.89 N +ATOM 506 CA SER A 160 -58.241 -11.355 -33.310 1.00 45.30 C +ATOM 507 C SER A 160 -59.206 -11.158 -34.471 1.00 45.20 C +ATOM 508 O SER A 160 -60.244 -10.504 -34.320 1.00 48.35 O +ATOM 509 CB SER A 160 -56.920 -10.637 -33.569 1.00 44.05 C +ATOM 510 OG SER A 160 -56.024 -10.866 -32.498 1.00 38.00 O +ATOM 511 N TRP A 161 -58.899 -11.747 -35.628 1.00 38.76 N +ATOM 512 CA TRP A 161 -59.749 -11.554 -36.797 1.00 41.41 C +ATOM 513 C TRP A 161 -61.154 -12.094 -36.571 1.00 41.10 C +ATOM 514 O TRP A 161 -62.115 -11.585 -37.158 1.00 38.00 O +ATOM 515 CB TRP A 161 -59.118 -12.216 -38.016 1.00 47.05 C +ATOM 516 CG TRP A 161 -59.016 -13.692 -37.892 1.00 50.57 C +ATOM 517 CD1 TRP A 161 -58.054 -14.391 -37.225 1.00 49.96 C +ATOM 518 CD2 TRP A 161 -59.906 -14.667 -38.456 1.00 52.43 C +ATOM 519 NE1 TRP A 161 -58.289 -15.741 -37.341 1.00 53.79 N +ATOM 520 CE2 TRP A 161 -59.419 -15.935 -38.092 1.00 52.20 C +ATOM 521 CE3 TRP A 161 -61.066 -14.588 -39.233 1.00 51.83 C +ATOM 522 CZ2 TRP A 161 -60.053 -17.114 -38.475 1.00 53.15 C +ATOM 523 CZ3 TRP A 161 -61.692 -15.762 -39.612 1.00 48.44 C +ATOM 524 CH2 TRP A 161 -61.187 -17.004 -39.233 1.00 50.27 C +ATOM 525 N VAL A 162 -61.294 -13.128 -35.745 1.00 38.00 N +ATOM 526 CA VAL A 162 -62.617 -13.667 -35.457 1.00 38.00 C +ATOM 527 C VAL A 162 -63.463 -12.646 -34.705 1.00 40.97 C +ATOM 528 O VAL A 162 -64.610 -12.374 -35.076 1.00 39.76 O +ATOM 529 CB VAL A 162 -62.498 -14.987 -34.678 1.00 44.31 C +ATOM 530 CG1 VAL A 162 -63.874 -15.574 -34.427 1.00 46.77 C +ATOM 531 CG2 VAL A 162 -61.641 -15.962 -35.452 1.00 47.73 C +ATOM 532 N GLN A 163 -62.917 -12.079 -33.625 1.00 50.09 N +ATOM 533 CA GLN A 163 -63.664 -11.077 -32.868 1.00 50.70 C +ATOM 534 C GLN A 163 -63.865 -9.798 -33.672 1.00 43.34 C +ATOM 535 O GLN A 163 -64.907 -9.141 -33.544 1.00 38.00 O +ATOM 536 CB GLN A 163 -62.957 -10.785 -31.542 1.00 49.45 C +ATOM 537 CG GLN A 163 -63.917 -10.618 -30.369 1.00 52.41 C +ATOM 538 CD GLN A 163 -64.701 -11.885 -30.065 1.00 52.49 C +ATOM 539 OE1 GLN A 163 -64.270 -12.994 -30.385 1.00 51.52 O +ATOM 540 NE2 GLN A 163 -65.874 -11.720 -29.466 1.00 49.73 N +ATOM 541 N PHE A 164 -62.899 -9.452 -34.526 1.00 43.41 N +ATOM 542 CA PHE A 164 -63.056 -8.298 -35.404 1.00 39.72 C +ATOM 543 C PHE A 164 -64.224 -8.491 -36.361 1.00 40.70 C +ATOM 544 O PHE A 164 -65.026 -7.572 -36.563 1.00 41.08 O +ATOM 545 CB PHE A 164 -61.755 -8.050 -36.171 1.00 38.00 C +ATOM 546 CG PHE A 164 -61.915 -7.149 -37.364 1.00 40.21 C +ATOM 547 CD1 PHE A 164 -62.413 -5.867 -37.218 1.00 44.16 C +ATOM 548 CD2 PHE A 164 -61.534 -7.572 -38.629 1.00 39.97 C +ATOM 549 CE1 PHE A 164 -62.558 -5.036 -38.310 1.00 41.92 C +ATOM 550 CE2 PHE A 164 -61.672 -6.741 -39.725 1.00 38.00 C +ATOM 551 CZ PHE A 164 -62.184 -5.473 -39.564 1.00 38.00 C +ATOM 552 N HIS A 165 -64.349 -9.688 -36.941 1.00 40.83 N +ATOM 553 CA HIS A 165 -65.449 -9.949 -37.863 1.00 39.77 C +ATOM 554 C HIS A 165 -66.780 -9.951 -37.130 1.00 41.29 C +ATOM 555 O HIS A 165 -67.773 -9.413 -37.631 1.00 45.34 O +ATOM 556 CB HIS A 165 -65.247 -11.275 -38.590 1.00 39.09 C +ATOM 557 CG HIS A 165 -64.143 -11.255 -39.596 1.00 44.94 C +ATOM 558 ND1 HIS A 165 -63.915 -12.299 -40.466 1.00 52.19 N +ATOM 559 CD2 HIS A 165 -63.192 -10.330 -39.864 1.00 47.64 C +ATOM 560 CE1 HIS A 165 -62.879 -12.013 -41.234 1.00 50.63 C +ATOM 561 NE2 HIS A 165 -62.419 -10.825 -40.887 1.00 45.74 N +ATOM 562 N LEU A 166 -66.831 -10.581 -35.957 1.00 41.16 N +ATOM 563 CA LEU A 166 -68.066 -10.578 -35.189 1.00 45.39 C +ATOM 564 C LEU A 166 -68.380 -9.214 -34.593 1.00 46.21 C +ATOM 565 O LEU A 166 -69.534 -8.978 -34.214 1.00 47.34 O +ATOM 566 CB LEU A 166 -67.989 -11.628 -34.083 1.00 47.29 C +ATOM 567 CG LEU A 166 -67.772 -13.065 -34.553 1.00 42.44 C +ATOM 568 CD1 LEU A 166 -67.002 -13.847 -33.508 1.00 38.58 C +ATOM 569 CD2 LEU A 166 -69.118 -13.722 -34.845 1.00 49.21 C +ATOM 570 N GLY A 167 -67.409 -8.300 -34.563 1.00 46.99 N +ATOM 571 CA GLY A 167 -67.570 -6.964 -34.027 1.00 55.43 C +ATOM 572 C GLY A 167 -67.949 -5.897 -35.028 1.00 47.00 C +ATOM 573 O GLY A 167 -68.019 -4.714 -34.676 1.00 38.33 O +ATOM 574 N ILE A 168 -68.191 -6.286 -36.276 1.00 48.06 N +ATOM 575 CA ILE A 168 -68.639 -5.358 -37.307 1.00 45.88 C +ATOM 576 C ILE A 168 -70.146 -5.177 -37.180 1.00 47.53 C +ATOM 577 O ILE A 168 -70.921 -6.116 -37.400 1.00 44.74 O +ATOM 578 CB ILE A 168 -68.250 -5.855 -38.706 1.00 46.04 C +ATOM 579 CG1 ILE A 168 -66.755 -6.164 -38.755 1.00 42.11 C +ATOM 580 CG2 ILE A 168 -68.578 -4.814 -39.753 1.00 51.20 C +ATOM 581 CD1 ILE A 168 -66.260 -6.536 -40.122 1.00 38.00 C +ATOM 582 N ASN A 169 -70.557 -3.963 -36.844 1.00 52.24 N +ATOM 583 CA ASN A 169 -71.941 -3.597 -36.607 1.00 52.94 C +ATOM 584 C ASN A 169 -72.377 -2.574 -37.648 1.00 51.48 C +ATOM 585 O ASN A 169 -71.587 -2.125 -38.482 1.00 49.26 O +ATOM 586 CB ASN A 169 -72.118 -3.036 -35.191 1.00 55.34 C +ATOM 587 CG ASN A 169 -71.085 -1.966 -34.842 1.00 62.66 C +ATOM 588 OD1 ASN A 169 -70.075 -1.800 -35.532 1.00 61.63 O +ATOM 589 ND2 ASN A 169 -71.339 -1.234 -33.761 1.00 60.30 N +ATOM 590 N ARG A 170 -73.650 -2.184 -37.571 1.00 56.37 N +ATOM 591 CA ARG A 170 -74.188 -1.179 -38.476 1.00 56.11 C +ATOM 592 C ARG A 170 -73.514 0.177 -38.313 1.00 54.31 C +ATOM 593 O ARG A 170 -73.637 1.024 -39.206 1.00 52.21 O +ATOM 594 CB ARG A 170 -75.696 -1.049 -38.246 1.00 58.70 C +ATOM 595 CG ARG A 170 -76.436 -0.278 -39.317 1.00 55.99 C +ATOM 596 CD ARG A 170 -77.931 -0.324 -39.079 1.00 60.21 C +ATOM 597 NE ARG A 170 -78.447 -1.686 -39.134 1.00 64.34 N +ATOM 598 CZ ARG A 170 -78.942 -2.242 -40.233 1.00 65.81 C +ATOM 599 NH1 ARG A 170 -78.983 -1.547 -41.361 1.00 64.31 N +ATOM 600 NH2 ARG A 170 -79.394 -3.486 -40.209 1.00 71.08 N +ATOM 601 N HIS A 171 -72.783 0.391 -37.221 1.00 57.45 N +ATOM 602 CA HIS A 171 -72.153 1.670 -36.932 1.00 58.49 C +ATOM 603 C HIS A 171 -70.724 1.759 -37.442 1.00 56.27 C +ATOM 604 O HIS A 171 -70.100 2.818 -37.324 1.00 59.24 O +ATOM 605 CB HIS A 171 -72.182 1.938 -35.427 1.00 62.60 C +ATOM 606 CG HIS A 171 -73.503 2.441 -34.939 1.00 69.52 C +ATOM 607 ND1 HIS A 171 -73.773 2.656 -33.605 1.00 80.70 N +ATOM 608 CD2 HIS A 171 -74.633 2.766 -35.612 1.00 64.42 C +ATOM 609 CE1 HIS A 171 -75.013 3.096 -33.478 1.00 88.70 C +ATOM 610 NE2 HIS A 171 -75.556 3.171 -34.680 1.00 82.69 N +ATOM 611 N GLY A 172 -70.194 0.694 -38.001 1.00 51.68 N +ATOM 612 CA GLY A 172 -68.886 0.766 -38.614 1.00 54.22 C +ATOM 613 C GLY A 172 -68.179 -0.568 -38.559 1.00 49.61 C +ATOM 614 O GLY A 172 -68.697 -1.560 -38.054 1.00 46.13 O +ATOM 615 N LEU A 173 -66.951 -0.552 -39.077 1.00 44.28 N +ATOM 616 CA LEU A 173 -66.152 -1.766 -39.149 1.00 42.79 C +ATOM 617 C LEU A 173 -65.680 -2.198 -37.768 1.00 44.48 C +ATOM 618 O LEU A 173 -65.660 -3.395 -37.456 1.00 45.91 O +ATOM 619 CB LEU A 173 -64.970 -1.546 -40.090 1.00 41.16 C +ATOM 620 CG LEU A 173 -64.965 -2.430 -41.337 1.00 43.29 C +ATOM 621 CD1 LEU A 173 -66.286 -2.324 -42.097 1.00 38.00 C +ATOM 622 CD2 LEU A 173 -63.776 -2.092 -42.237 1.00 40.44 C +ATOM 623 N TYR A 174 -65.269 -1.249 -36.938 1.00 43.64 N +ATOM 624 CA TYR A 174 -64.765 -1.555 -35.611 1.00 47.55 C +ATOM 625 C TYR A 174 -65.424 -0.642 -34.580 1.00 49.18 C +ATOM 626 O TYR A 174 -66.245 0.222 -34.907 1.00 42.76 O +ATOM 627 CB TYR A 174 -63.235 -1.463 -35.579 1.00 45.72 C +ATOM 628 CG TYR A 174 -62.655 -0.220 -36.210 1.00 46.18 C +ATOM 629 CD1 TYR A 174 -62.574 -0.093 -37.590 1.00 53.22 C +ATOM 630 CD2 TYR A 174 -62.162 0.813 -35.429 1.00 47.79 C +ATOM 631 CE1 TYR A 174 -62.040 1.036 -38.177 1.00 52.16 C +ATOM 632 CE2 TYR A 174 -61.616 1.946 -36.010 1.00 52.77 C +ATOM 633 CZ TYR A 174 -61.564 2.051 -37.386 1.00 46.65 C +ATOM 634 OH TYR A 174 -61.033 3.169 -37.979 1.00 42.93 O +ATOM 635 N SER A 175 -65.080 -0.871 -33.315 1.00 53.67 N +ATOM 636 CA SER A 175 -65.633 -0.123 -32.199 1.00 44.77 C +ATOM 637 C SER A 175 -64.765 1.084 -31.883 1.00 45.89 C +ATOM 638 O SER A 175 -63.559 1.106 -32.145 1.00 44.22 O +ATOM 639 CB SER A 175 -65.748 -1.001 -30.954 1.00 47.60 C +ATOM 640 OG SER A 175 -66.186 -2.307 -31.280 1.00 62.41 O +ATOM 641 N ARG A 176 -65.394 2.082 -31.274 1.00 45.50 N +ATOM 642 CA ARG A 176 -64.683 3.289 -30.885 1.00 43.12 C +ATOM 643 C ARG A 176 -63.748 2.961 -29.731 1.00 40.19 C +ATOM 644 O ARG A 176 -64.193 2.454 -28.695 1.00 42.69 O +ATOM 645 CB ARG A 176 -65.677 4.381 -30.504 1.00 38.00 C +ATOM 646 CG ARG A 176 -65.024 5.687 -30.130 1.00 44.17 C +ATOM 647 CD ARG A 176 -65.885 6.849 -30.561 1.00 45.97 C +ATOM 648 NE ARG A 176 -67.221 6.783 -29.984 1.00 49.52 N +ATOM 649 CZ ARG A 176 -68.235 7.551 -30.367 1.00 59.94 C +ATOM 650 NH1 ARG A 176 -68.072 8.442 -31.338 1.00 56.40 N +ATOM 651 NH2 ARG A 176 -69.417 7.425 -29.782 1.00 67.33 N +ATOM 652 N SER A 177 -62.455 3.218 -29.921 1.00 38.00 N +ATOM 653 CA SER A 177 -61.421 2.840 -28.959 1.00 47.93 C +ATOM 654 C SER A 177 -61.580 1.377 -28.555 1.00 50.31 C +ATOM 655 O SER A 177 -61.796 1.038 -27.390 1.00 44.63 O +ATOM 656 CB SER A 177 -61.431 3.753 -27.731 1.00 48.38 C +ATOM 657 OG SER A 177 -60.948 5.044 -28.053 1.00 57.28 O +ATOM 658 N SER A 178 -61.484 0.507 -29.563 1.00 53.71 N +ATOM 659 CA SER A 178 -61.712 -0.918 -29.368 1.00 49.83 C +ATOM 660 C SER A 178 -60.415 -1.607 -28.969 1.00 46.35 C +ATOM 661 O SER A 178 -59.404 -1.466 -29.666 1.00 43.99 O +ATOM 662 CB SER A 178 -62.260 -1.556 -30.639 1.00 46.90 C +ATOM 663 OG SER A 178 -62.282 -2.970 -30.540 1.00 50.29 O +ATOM 664 N PRO A 179 -60.408 -2.355 -27.867 1.00 46.81 N +ATOM 665 CA PRO A 179 -59.216 -3.147 -27.534 1.00 49.27 C +ATOM 666 C PRO A 179 -59.004 -4.317 -28.479 1.00 49.27 C +ATOM 667 O PRO A 179 -57.887 -4.847 -28.548 1.00 43.10 O +ATOM 668 CB PRO A 179 -59.500 -3.616 -26.102 1.00 52.31 C +ATOM 669 CG PRO A 179 -61.001 -3.647 -26.015 1.00 46.86 C +ATOM 670 CD PRO A 179 -61.491 -2.522 -26.882 1.00 43.90 C +ATOM 671 N VAL A 180 -60.051 -4.730 -29.200 1.00 51.52 N +ATOM 672 CA VAL A 180 -59.936 -5.806 -30.180 1.00 44.52 C +ATOM 673 C VAL A 180 -59.024 -5.385 -31.322 1.00 41.13 C +ATOM 674 O VAL A 180 -58.110 -6.116 -31.722 1.00 39.89 O +ATOM 675 CB VAL A 180 -61.335 -6.183 -30.702 1.00 38.00 C +ATOM 676 CG1 VAL A 180 -61.236 -7.172 -31.856 1.00 40.82 C +ATOM 677 CG2 VAL A 180 -62.201 -6.721 -29.576 1.00 38.18 C +ATOM 678 N VAL A 181 -59.253 -4.186 -31.849 1.00 39.65 N +ATOM 679 CA VAL A 181 -58.466 -3.697 -32.969 1.00 38.09 C +ATOM 680 C VAL A 181 -57.020 -3.485 -32.548 1.00 38.00 C +ATOM 681 O VAL A 181 -56.090 -3.733 -33.321 1.00 38.06 O +ATOM 682 CB VAL A 181 -59.108 -2.415 -33.517 1.00 38.00 C +ATOM 683 CG1 VAL A 181 -58.464 -2.010 -34.815 1.00 38.00 C +ATOM 684 CG2 VAL A 181 -60.596 -2.631 -33.685 1.00 38.00 C +ATOM 685 N SER A 182 -56.807 -3.047 -31.308 1.00 38.00 N +ATOM 686 CA SER A 182 -55.450 -2.865 -30.809 1.00 40.49 C +ATOM 687 C SER A 182 -54.688 -4.184 -30.806 1.00 43.56 C +ATOM 688 O SER A 182 -53.495 -4.223 -31.130 1.00 45.85 O +ATOM 689 CB SER A 182 -55.502 -2.271 -29.403 1.00 50.23 C +ATOM 690 OG SER A 182 -56.118 -0.996 -29.423 1.00 50.75 O +ATOM 691 N LYS A 183 -55.362 -5.273 -30.425 1.00 44.72 N +ATOM 692 CA LYS A 183 -54.758 -6.599 -30.503 1.00 43.11 C +ATOM 693 C LYS A 183 -54.648 -7.063 -31.946 1.00 40.33 C +ATOM 694 O LYS A 183 -53.648 -7.677 -32.335 1.00 42.63 O +ATOM 695 CB LYS A 183 -55.580 -7.593 -29.682 1.00 48.45 C +ATOM 696 CG LYS A 183 -55.032 -9.016 -29.642 1.00 46.26 C +ATOM 697 CD LYS A 183 -53.682 -9.085 -28.945 1.00 43.46 C +ATOM 698 CE LYS A 183 -53.364 -10.503 -28.500 1.00 38.00 C +ATOM 699 NZ LYS A 183 -53.533 -11.492 -29.592 1.00 38.00 N +ATOM 700 N LEU A 184 -55.666 -6.764 -32.753 1.00 40.14 N +ATOM 701 CA LEU A 184 -55.641 -7.148 -34.158 1.00 41.12 C +ATOM 702 C LEU A 184 -54.436 -6.539 -34.863 1.00 38.57 C +ATOM 703 O LEU A 184 -53.703 -7.233 -35.577 1.00 38.00 O +ATOM 704 CB LEU A 184 -56.955 -6.721 -34.821 1.00 38.00 C +ATOM 705 CG LEU A 184 -57.151 -6.981 -36.309 1.00 38.00 C +ATOM 706 CD1 LEU A 184 -56.917 -8.437 -36.589 1.00 38.00 C +ATOM 707 CD2 LEU A 184 -58.556 -6.603 -36.704 1.00 38.00 C +ATOM 708 N LEU A 185 -54.192 -5.246 -34.636 1.00 40.01 N +ATOM 709 CA LEU A 185 -53.029 -4.591 -35.223 1.00 38.82 C +ATOM 710 C LEU A 185 -51.730 -5.217 -34.731 1.00 38.97 C +ATOM 711 O LEU A 185 -50.793 -5.410 -35.514 1.00 40.82 O +ATOM 712 CB LEU A 185 -53.057 -3.092 -34.916 1.00 41.62 C +ATOM 713 CG LEU A 185 -53.922 -2.191 -35.804 1.00 38.00 C +ATOM 714 CD1 LEU A 185 -54.955 -1.465 -34.983 1.00 38.00 C +ATOM 715 CD2 LEU A 185 -53.068 -1.173 -36.530 1.00 48.32 C +ATOM 716 N GLN A 186 -51.646 -5.529 -33.435 1.00 40.03 N +ATOM 717 CA GLN A 186 -50.426 -6.131 -32.904 1.00 44.40 C +ATOM 718 C GLN A 186 -50.216 -7.540 -33.445 1.00 41.94 C +ATOM 719 O GLN A 186 -49.071 -7.981 -33.600 1.00 38.00 O +ATOM 720 CB GLN A 186 -50.466 -6.145 -31.374 1.00 46.03 C +ATOM 721 CG GLN A 186 -50.281 -4.780 -30.722 1.00 52.75 C +ATOM 722 CD GLN A 186 -48.963 -4.115 -31.093 1.00 55.63 C +ATOM 723 OE1 GLN A 186 -48.944 -3.028 -31.677 1.00 57.32 O +ATOM 724 NE2 GLN A 186 -47.855 -4.765 -30.753 1.00 53.28 N +ATOM 725 N ASP A 187 -51.304 -8.253 -33.750 1.00 42.55 N +ATOM 726 CA ASP A 187 -51.172 -9.605 -34.282 1.00 42.58 C +ATOM 727 C ASP A 187 -50.628 -9.582 -35.702 1.00 39.32 C +ATOM 728 O ASP A 187 -49.678 -10.304 -36.026 1.00 38.00 O +ATOM 729 CB ASP A 187 -52.519 -10.331 -34.245 1.00 43.67 C +ATOM 730 CG ASP A 187 -52.896 -10.788 -32.857 1.00 43.36 C +ATOM 731 OD1 ASP A 187 -52.153 -10.460 -31.910 1.00 46.99 O +ATOM 732 OD2 ASP A 187 -53.910 -11.507 -32.717 1.00 44.31 O +ATOM 733 N MET A 188 -51.195 -8.731 -36.556 1.00 38.00 N +ATOM 734 CA MET A 188 -50.724 -8.650 -37.929 1.00 38.00 C +ATOM 735 C MET A 188 -49.272 -8.199 -38.008 1.00 38.00 C +ATOM 736 O MET A 188 -48.615 -8.446 -39.025 1.00 38.00 O +ATOM 737 CB MET A 188 -51.628 -7.708 -38.724 1.00 38.00 C +ATOM 738 CG MET A 188 -53.102 -8.071 -38.637 1.00 38.00 C +ATOM 739 SD MET A 188 -54.128 -7.299 -39.903 1.00 38.00 S +ATOM 740 CE MET A 188 -54.334 -5.654 -39.252 1.00 38.00 C +ATOM 741 N ARG A 189 -48.743 -7.585 -36.949 1.00 38.00 N +ATOM 742 CA ARG A 189 -47.355 -7.147 -36.958 1.00 38.00 C +ATOM 743 C ARG A 189 -46.388 -8.251 -36.562 1.00 40.74 C +ATOM 744 O ARG A 189 -45.250 -8.266 -37.044 1.00 38.00 O +ATOM 745 CB ARG A 189 -47.153 -5.955 -36.012 1.00 43.07 C +ATOM 746 CG ARG A 189 -45.833 -5.203 -36.241 1.00 46.91 C +ATOM 747 CD ARG A 189 -45.259 -4.569 -34.973 1.00 51.32 C +ATOM 748 NE ARG A 189 -46.271 -3.867 -34.188 1.00 64.00 N +ATOM 749 CZ ARG A 189 -46.726 -2.650 -34.469 1.00 69.27 C +ATOM 750 NH1 ARG A 189 -46.264 -2.003 -35.528 1.00 69.84 N +ATOM 751 NH2 ARG A 189 -47.651 -2.084 -33.700 1.00 63.08 N +ATOM 752 N HIS A 190 -46.820 -9.191 -35.717 1.00 47.86 N +ATOM 753 CA HIS A 190 -45.917 -10.169 -35.121 1.00 50.28 C +ATOM 754 C HIS A 190 -46.206 -11.616 -35.484 1.00 44.55 C +ATOM 755 O HIS A 190 -45.262 -12.407 -35.570 1.00 40.14 O +ATOM 756 CB HIS A 190 -45.939 -10.054 -33.588 1.00 47.44 C +ATOM 757 CG HIS A 190 -45.500 -8.722 -33.075 1.00 46.21 C +ATOM 758 ND1 HIS A 190 -44.182 -8.437 -32.791 1.00 51.21 N +ATOM 759 CD2 HIS A 190 -46.201 -7.603 -32.778 1.00 45.70 C +ATOM 760 CE1 HIS A 190 -44.088 -7.195 -32.353 1.00 60.92 C +ATOM 761 NE2 HIS A 190 -45.299 -6.668 -32.332 1.00 63.70 N +ATOM 762 N PHE A 191 -47.465 -11.984 -35.698 1.00 44.23 N +ATOM 763 CA PHE A 191 -47.794 -13.375 -35.961 1.00 47.10 C +ATOM 764 C PHE A 191 -47.054 -13.859 -37.205 1.00 51.80 C +ATOM 765 O PHE A 191 -46.945 -13.119 -38.192 1.00 55.81 O +ATOM 766 CB PHE A 191 -49.303 -13.537 -36.147 1.00 44.10 C +ATOM 767 CG PHE A 191 -50.062 -13.716 -34.861 1.00 45.19 C +ATOM 768 CD1 PHE A 191 -49.852 -12.863 -33.791 1.00 44.59 C +ATOM 769 CD2 PHE A 191 -51.030 -14.699 -34.744 1.00 43.08 C +ATOM 770 CE1 PHE A 191 -50.558 -13.015 -32.616 1.00 38.00 C +ATOM 771 CE2 PHE A 191 -51.748 -14.848 -33.572 1.00 43.57 C +ATOM 772 CZ PHE A 191 -51.513 -14.003 -32.508 1.00 38.00 C +ATOM 773 N PRO A 192 -46.532 -15.081 -37.195 1.00 50.20 N +ATOM 774 CA PRO A 192 -45.825 -15.588 -38.373 1.00 54.62 C +ATOM 775 C PRO A 192 -46.800 -15.959 -39.481 1.00 54.96 C +ATOM 776 O PRO A 192 -47.977 -16.252 -39.250 1.00 49.70 O +ATOM 777 CB PRO A 192 -45.089 -16.819 -37.837 1.00 50.93 C +ATOM 778 CG PRO A 192 -45.970 -17.302 -36.735 1.00 46.33 C +ATOM 779 CD PRO A 192 -46.561 -16.068 -36.102 1.00 45.16 C +ATOM 780 N THR A 193 -46.285 -15.937 -40.706 1.00 48.72 N +ATOM 781 CA THR A 193 -47.078 -16.279 -41.876 1.00 47.94 C +ATOM 782 C THR A 193 -47.028 -17.780 -42.126 1.00 44.81 C +ATOM 783 O THR A 193 -46.010 -18.433 -41.877 1.00 42.35 O +ATOM 784 CB THR A 193 -46.585 -15.514 -43.106 1.00 46.02 C +ATOM 785 OG1 THR A 193 -45.174 -15.706 -43.257 1.00 45.26 O +ATOM 786 CG2 THR A 193 -46.887 -14.032 -42.969 1.00 46.79 C +ATOM 787 N ILE A 194 -48.154 -18.328 -42.575 1.00 44.98 N +ATOM 788 CA ILE A 194 -48.263 -19.752 -42.874 1.00 48.07 C +ATOM 789 C ILE A 194 -48.606 -20.031 -44.328 1.00 48.42 C +ATOM 790 O ILE A 194 -48.605 -21.204 -44.732 1.00 52.40 O +ATOM 791 CB ILE A 194 -49.298 -20.441 -41.960 1.00 44.87 C +ATOM 792 CG1 ILE A 194 -50.714 -19.957 -42.294 1.00 44.13 C +ATOM 793 CG2 ILE A 194 -48.969 -20.194 -40.505 1.00 43.79 C +ATOM 794 CD1 ILE A 194 -51.785 -20.580 -41.430 1.00 45.74 C +ATOM 795 N SER A 195 -48.891 -19.009 -45.126 1.00 45.25 N +ATOM 796 CA SER A 195 -49.417 -19.196 -46.467 1.00 39.12 C +ATOM 797 C SER A 195 -49.385 -17.858 -47.184 1.00 42.67 C +ATOM 798 O SER A 195 -49.521 -16.808 -46.553 1.00 51.49 O +ATOM 799 CB SER A 195 -50.848 -19.747 -46.405 1.00 44.49 C +ATOM 800 OG SER A 195 -51.606 -19.405 -47.549 1.00 44.15 O +ATOM 801 N ALA A 196 -49.218 -17.905 -48.505 1.00 45.68 N +ATOM 802 CA ALA A 196 -49.246 -16.703 -49.330 1.00 40.75 C +ATOM 803 C ALA A 196 -49.827 -17.059 -50.690 1.00 38.00 C +ATOM 804 O ALA A 196 -49.443 -18.071 -51.281 1.00 39.90 O +ATOM 805 CB ALA A 196 -47.842 -16.097 -49.481 1.00 38.00 C +ATOM 806 N ASP A 197 -50.757 -16.239 -51.178 1.00 38.00 N +ATOM 807 CA ASP A 197 -51.370 -16.487 -52.478 1.00 42.30 C +ATOM 808 C ASP A 197 -51.406 -15.211 -53.315 1.00 47.81 C +ATOM 809 O ASP A 197 -50.819 -14.192 -52.936 1.00 52.61 O +ATOM 810 CB ASP A 197 -52.784 -17.055 -52.299 1.00 48.24 C +ATOM 811 CG ASP A 197 -53.261 -17.863 -53.501 1.00 49.20 C +ATOM 812 OD1 ASP A 197 -52.851 -17.559 -54.637 1.00 50.76 O +ATOM 813 OD2 ASP A 197 -54.052 -18.809 -53.307 1.00 54.58 O +ATOM 814 N TYR A 198 -52.097 -15.256 -54.452 1.00 47.14 N +ATOM 815 CA TYR A 198 -52.195 -14.121 -55.360 1.00 49.31 C +ATOM 816 C TYR A 198 -53.461 -13.305 -55.157 1.00 50.40 C +ATOM 817 O TYR A 198 -53.626 -12.277 -55.821 1.00 60.71 O +ATOM 818 CB TYR A 198 -52.123 -14.605 -56.813 1.00 50.63 C +ATOM 819 CG TYR A 198 -50.789 -14.384 -57.496 1.00 42.33 C +ATOM 820 CD1 TYR A 198 -50.137 -13.166 -57.407 1.00 48.63 C +ATOM 821 CD2 TYR A 198 -50.188 -15.393 -58.232 1.00 45.11 C +ATOM 822 CE1 TYR A 198 -48.927 -12.956 -58.035 1.00 54.55 C +ATOM 823 CE2 TYR A 198 -48.974 -15.197 -58.856 1.00 48.61 C +ATOM 824 CZ TYR A 198 -48.347 -13.973 -58.756 1.00 54.69 C +ATOM 825 OH TYR A 198 -47.136 -13.751 -59.378 1.00 58.83 O +ATOM 826 N SER A 199 -54.347 -13.736 -54.259 1.00 46.26 N +ATOM 827 CA SER A 199 -55.636 -13.093 -54.016 1.00 57.07 C +ATOM 828 C SER A 199 -56.577 -13.211 -55.204 1.00 55.30 C +ATOM 829 O SER A 199 -56.150 -13.475 -56.331 1.00 56.71 O +ATOM 830 CB SER A 199 -55.461 -11.609 -53.676 1.00 59.81 C +ATOM 831 OG SER A 199 -55.217 -10.855 -54.856 1.00 52.12 O +ATOM 832 N GLN A 200 -57.860 -12.968 -54.964 1.00 59.07 N +ATOM 833 CA GLN A 200 -58.818 -12.869 -56.051 1.00 63.99 C +ATOM 834 C GLN A 200 -58.600 -11.548 -56.772 1.00 73.16 C +ATOM 835 O GLN A 200 -57.534 -10.938 -56.634 1.00 72.48 O +ATOM 836 CB GLN A 200 -60.244 -12.972 -55.522 1.00 67.72 C +ATOM 837 CG GLN A 200 -61.153 -13.790 -56.399 1.00 62.99 C +ATOM 838 CD GLN A 200 -61.139 -15.262 -56.035 1.00 66.18 C +ATOM 839 OE1 GLN A 200 -62.050 -16.000 -56.397 1.00 78.45 O +ATOM 840 NE2 GLN A 200 -60.110 -15.694 -55.311 1.00 52.31 N +ATOM 841 N ASP A 201 -59.586 -11.108 -57.558 1.00 75.98 N +ATOM 842 CA ASP A 201 -59.523 -9.843 -58.291 1.00 83.12 C +ATOM 843 C ASP A 201 -58.412 -9.880 -59.342 1.00 75.75 C +ATOM 844 O ASP A 201 -58.614 -9.443 -60.480 1.00 75.13 O +ATOM 845 CB ASP A 201 -59.377 -8.668 -57.306 1.00 82.70 C +ATOM 846 CG ASP A 201 -58.094 -7.878 -57.496 1.00 76.91 C +ATOM 847 OD1 ASP A 201 -58.046 -7.033 -58.415 1.00 77.36 O +ATOM 848 OD2 ASP A 201 -57.145 -8.088 -56.710 1.00 69.09 O +ATOM 849 N GLU A 202 -57.241 -10.398 -58.974 1.00 71.66 N +ATOM 850 CA GLU A 202 -56.345 -11.048 -59.918 1.00 63.49 C +ATOM 851 C GLU A 202 -56.818 -12.497 -60.036 1.00 65.89 C +ATOM 852 O GLU A 202 -57.976 -12.795 -59.731 1.00 70.55 O +ATOM 853 CB GLU A 202 -54.888 -10.920 -59.451 1.00 60.17 C +ATOM 854 CG GLU A 202 -53.842 -11.248 -60.522 1.00 61.43 C +ATOM 855 CD GLU A 202 -53.091 -12.537 -60.233 1.00 57.41 C +ATOM 856 OE1 GLU A 202 -52.616 -12.702 -59.097 1.00 49.89 O +ATOM 857 OE2 GLU A 202 -52.996 -13.397 -61.133 1.00 55.12 O +ATOM 858 N LYS A 203 -55.954 -13.405 -60.492 1.00 65.98 N +ATOM 859 CA LYS A 203 -56.252 -14.833 -60.521 1.00 73.07 C +ATOM 860 C LYS A 203 -57.438 -15.130 -61.432 1.00 70.28 C +ATOM 861 O LYS A 203 -57.343 -15.977 -62.325 1.00 72.00 O +ATOM 862 CB LYS A 203 -56.514 -15.343 -59.099 1.00 74.23 C +ATOM 863 CG LYS A 203 -56.081 -16.773 -58.827 1.00 68.60 C +ATOM 864 CD LYS A 203 -55.898 -16.978 -57.327 1.00 70.67 C +ATOM 865 CE LYS A 203 -55.890 -18.441 -56.929 1.00 64.06 C +ATOM 866 NZ LYS A 203 -55.553 -18.586 -55.484 1.00 55.05 N +ATOM 867 N ALA A 204 -58.557 -14.435 -61.215 1.00 74.60 N +ATOM 868 CA ALA A 204 -59.703 -14.532 -62.108 1.00 67.01 C +ATOM 869 C ALA A 204 -59.466 -13.841 -63.442 1.00 63.18 C +ATOM 870 O ALA A 204 -60.319 -13.946 -64.330 1.00 56.17 O +ATOM 871 CB ALA A 204 -60.947 -13.944 -61.433 1.00 66.07 C +ATOM 872 N LEU A 205 -58.337 -13.145 -63.606 1.00 68.75 N +ATOM 873 CA LEU A 205 -57.979 -12.586 -64.906 1.00 57.71 C +ATOM 874 C LEU A 205 -57.527 -13.651 -65.895 1.00 52.66 C +ATOM 875 O LEU A 205 -57.539 -13.394 -67.104 1.00 55.07 O +ATOM 876 CB LEU A 205 -56.872 -11.541 -64.752 1.00 51.50 C +ATOM 877 CG LEU A 205 -57.241 -10.213 -64.092 1.00 56.24 C +ATOM 878 CD1 LEU A 205 -56.086 -9.230 -64.209 1.00 63.57 C +ATOM 879 CD2 LEU A 205 -58.515 -9.634 -64.693 1.00 54.75 C +ATOM 880 N LEU A 206 -57.125 -14.826 -65.407 1.00 50.12 N +ATOM 881 CA LEU A 206 -56.697 -15.950 -66.233 1.00 45.99 C +ATOM 882 C LEU A 206 -55.447 -15.581 -67.024 1.00 44.92 C +ATOM 883 O LEU A 206 -54.351 -16.069 -66.726 1.00 38.00 O +ATOM 884 CB LEU A 206 -57.829 -16.398 -67.168 1.00 51.71 C +ATOM 885 CG LEU A 206 -59.051 -17.031 -66.491 1.00 52.59 C +ATOM 886 CD1 LEU A 206 -60.000 -17.659 -67.503 1.00 59.47 C +ATOM 887 CD2 LEU A 206 -58.624 -18.064 -65.473 1.00 48.68 C +ATOM 888 N GLY A 207 -55.602 -14.691 -68.007 1.00 58.17 N +ATOM 889 CA GLY A 207 -54.505 -14.203 -68.825 1.00 53.08 C +ATOM 890 C GLY A 207 -53.529 -13.346 -68.046 1.00 43.33 C +ATOM 891 O GLY A 207 -52.722 -13.893 -67.290 1.00 46.98 O +ATOM 892 N ALA A 208 -53.560 -12.022 -68.204 1.00 40.68 N +ATOM 893 CA ALA A 208 -54.392 -11.283 -69.153 1.00 45.43 C +ATOM 894 C ALA A 208 -53.744 -9.915 -69.338 1.00 59.45 C +ATOM 895 O ALA A 208 -54.227 -8.904 -68.821 1.00 60.50 O +ATOM 896 CB ALA A 208 -55.824 -11.135 -68.660 1.00 46.91 C +ATOM 897 N CYS A 209 -52.632 -9.895 -70.062 1.00 62.85 N +ATOM 898 CA CYS A 209 -51.772 -8.722 -70.158 1.00 55.22 C +ATOM 899 C CYS A 209 -51.950 -8.084 -71.528 1.00 54.89 C +ATOM 900 O CYS A 209 -51.592 -8.679 -72.549 1.00 64.78 O +ATOM 901 CB CYS A 209 -50.322 -9.122 -69.918 1.00 53.78 C +ATOM 902 SG CYS A 209 -49.379 -7.886 -69.038 1.00 70.49 S +ATOM 903 N ASP A 210 -52.498 -6.873 -71.543 1.00 58.42 N +ATOM 904 CA ASP A 210 -52.664 -6.065 -72.750 1.00 56.67 C +ATOM 905 C ASP A 210 -51.813 -4.813 -72.561 1.00 59.44 C +ATOM 906 O ASP A 210 -52.249 -3.845 -71.935 1.00 62.37 O +ATOM 907 CB ASP A 210 -54.132 -5.720 -72.983 1.00 55.97 C +ATOM 908 CG ASP A 210 -54.373 -5.039 -74.320 1.00 65.12 C +ATOM 909 OD1 ASP A 210 -53.420 -4.923 -75.123 1.00 66.38 O +ATOM 910 OD2 ASP A 210 -55.520 -4.594 -74.554 1.00 66.62 O +ATOM 911 N CYS A 211 -50.587 -4.841 -73.089 1.00 58.08 N +ATOM 912 CA CYS A 211 -49.675 -3.711 -72.935 1.00 60.22 C +ATOM 913 C CYS A 211 -50.187 -2.435 -73.592 1.00 68.94 C +ATOM 914 O CYS A 211 -49.640 -1.358 -73.324 1.00 61.97 O +ATOM 915 CB CYS A 211 -48.308 -4.077 -73.509 1.00 57.86 C +ATOM 916 SG CYS A 211 -47.556 -5.480 -72.676 1.00 73.84 S +ATOM 917 N THR A 212 -51.217 -2.534 -74.439 1.00 74.33 N +ATOM 918 CA THR A 212 -51.852 -1.368 -75.040 1.00 67.54 C +ATOM 919 C THR A 212 -52.829 -0.709 -74.073 1.00 64.63 C +ATOM 920 O THR A 212 -52.987 0.518 -74.089 1.00 62.28 O +ATOM 921 CB THR A 212 -52.570 -1.786 -76.328 1.00 63.02 C +ATOM 922 OG1 THR A 212 -51.600 -2.183 -77.304 1.00 64.62 O +ATOM 923 CG2 THR A 212 -53.386 -0.640 -76.898 1.00 68.48 C +ATOM 924 N GLN A 213 -53.474 -1.508 -73.225 1.00 68.06 N +ATOM 925 CA GLN A 213 -54.389 -1.000 -72.212 1.00 63.60 C +ATOM 926 C GLN A 213 -53.673 -0.025 -71.290 1.00 57.18 C +ATOM 927 O GLN A 213 -52.746 -0.405 -70.568 1.00 52.08 O +ATOM 928 CB GLN A 213 -54.952 -2.164 -71.404 1.00 61.68 C +ATOM 929 CG GLN A 213 -56.380 -2.001 -70.948 1.00 60.71 C +ATOM 930 CD GLN A 213 -56.875 -3.247 -70.243 1.00 64.98 C +ATOM 931 OE1 GLN A 213 -56.097 -4.169 -69.980 1.00 58.00 O +ATOM 932 NE2 GLN A 213 -58.172 -3.292 -69.945 1.00 72.48 N +ATOM 933 N ILE A 214 -54.119 1.229 -71.294 1.00 59.04 N +ATOM 934 CA ILE A 214 -53.475 2.229 -70.453 1.00 49.47 C +ATOM 935 C ILE A 214 -53.921 2.071 -69.009 1.00 44.51 C +ATOM 936 O ILE A 214 -53.098 2.070 -68.088 1.00 39.01 O +ATOM 937 CB ILE A 214 -53.782 3.636 -70.998 1.00 48.91 C +ATOM 938 CG1 ILE A 214 -53.301 3.758 -72.444 1.00 49.39 C +ATOM 939 CG2 ILE A 214 -53.119 4.697 -70.137 1.00 46.74 C +ATOM 940 CD1 ILE A 214 -53.589 5.097 -73.071 1.00 48.51 C +ATOM 941 N VAL A 215 -55.222 1.884 -68.795 1.00 49.46 N +ATOM 942 CA VAL A 215 -55.766 1.656 -67.463 1.00 50.55 C +ATOM 943 C VAL A 215 -56.203 0.202 -67.371 1.00 55.13 C +ATOM 944 O VAL A 215 -57.399 -0.108 -67.441 1.00 49.60 O +ATOM 945 CB VAL A 215 -56.935 2.606 -67.147 1.00 56.78 C +ATOM 946 CG1 VAL A 215 -57.233 2.590 -65.658 1.00 54.08 C +ATOM 947 CG2 VAL A 215 -56.623 4.016 -67.616 1.00 60.03 C +ATOM 948 N LYS A 216 -55.228 -0.698 -67.269 1.00 57.95 N +ATOM 949 CA LYS A 216 -55.519 -2.107 -67.069 1.00 55.29 C +ATOM 950 C LYS A 216 -56.248 -2.298 -65.738 1.00 53.88 C +ATOM 951 O LYS A 216 -56.055 -1.511 -64.807 1.00 61.38 O +ATOM 952 CB LYS A 216 -54.221 -2.910 -67.105 1.00 52.58 C +ATOM 953 CG LYS A 216 -52.984 -2.093 -66.751 1.00 49.35 C +ATOM 954 CD LYS A 216 -51.703 -2.879 -67.011 1.00 49.94 C +ATOM 955 CE LYS A 216 -51.479 -3.133 -68.491 1.00 45.17 C +ATOM 956 NZ LYS A 216 -50.841 -1.961 -69.146 1.00 50.31 N +ATOM 957 N PRO A 217 -57.075 -3.342 -65.614 1.00 54.63 N +ATOM 958 CA PRO A 217 -57.933 -3.473 -64.428 1.00 65.21 C +ATOM 959 C PRO A 217 -57.123 -3.575 -63.142 1.00 77.31 C +ATOM 960 O PRO A 217 -55.918 -3.838 -63.154 1.00 75.39 O +ATOM 961 CB PRO A 217 -58.721 -4.761 -64.697 1.00 53.49 C +ATOM 962 CG PRO A 217 -57.880 -5.520 -65.652 1.00 49.13 C +ATOM 963 CD PRO A 217 -57.248 -4.483 -66.528 1.00 56.38 C +ATOM 964 N SER A 218 -57.811 -3.376 -62.013 1.00 70.33 N +ATOM 965 CA SER A 218 -57.141 -3.316 -60.716 1.00 72.39 C +ATOM 966 C SER A 218 -56.663 -4.691 -60.261 1.00 66.85 C +ATOM 967 O SER A 218 -56.367 -4.887 -59.079 1.00 77.49 O +ATOM 968 CB SER A 218 -58.080 -2.698 -59.665 1.00 80.79 C +ATOM 969 OG SER A 218 -57.443 -2.518 -58.405 1.00 74.97 O +ATOM 970 N GLY A 219 -56.526 -5.632 -61.190 1.00 59.01 N +ATOM 971 CA GLY A 219 -56.067 -6.956 -60.833 1.00 59.66 C +ATOM 972 C GLY A 219 -54.618 -7.196 -61.191 1.00 60.84 C +ATOM 973 O GLY A 219 -54.000 -8.144 -60.703 1.00 59.00 O +ATOM 974 N VAL A 220 -54.039 -6.314 -61.996 1.00 61.81 N +ATOM 975 CA VAL A 220 -52.647 -6.480 -62.391 1.00 58.35 C +ATOM 976 C VAL A 220 -51.774 -5.609 -61.502 1.00 60.00 C +ATOM 977 O VAL A 220 -50.841 -4.962 -61.982 1.00 72.16 O +ATOM 978 CB VAL A 220 -52.444 -6.126 -63.876 1.00 59.33 C +ATOM 979 CG1 VAL A 220 -53.040 -7.199 -64.765 1.00 65.27 C +ATOM 980 CG2 VAL A 220 -53.095 -4.792 -64.180 1.00 61.78 C +ATOM 981 N HIS A 221 -52.044 -5.608 -60.202 1.00 48.92 N +ATOM 982 CA HIS A 221 -51.278 -4.812 -59.260 1.00 44.18 C +ATOM 983 C HIS A 221 -50.634 -5.727 -58.231 1.00 38.67 C +ATOM 984 O HIS A 221 -51.210 -6.748 -57.841 1.00 39.31 O +ATOM 985 CB HIS A 221 -52.167 -3.771 -58.558 1.00 60.39 C +ATOM 986 CG HIS A 221 -52.684 -2.693 -59.464 1.00 63.35 C +ATOM 987 ND1 HIS A 221 -51.967 -2.205 -60.536 1.00 65.19 N +ATOM 988 CD2 HIS A 221 -53.861 -2.023 -59.465 1.00 57.40 C +ATOM 989 CE1 HIS A 221 -52.675 -1.274 -61.151 1.00 57.32 C +ATOM 990 NE2 HIS A 221 -53.829 -1.146 -60.522 1.00 57.54 N +ATOM 991 N LEU A 222 -49.439 -5.344 -57.786 1.00 44.93 N +ATOM 992 CA LEU A 222 -48.636 -6.171 -56.882 1.00 44.52 C +ATOM 993 C LEU A 222 -49.243 -6.146 -55.486 1.00 41.64 C +ATOM 994 O LEU A 222 -49.032 -5.206 -54.717 1.00 41.78 O +ATOM 995 CB LEU A 222 -47.192 -5.685 -56.853 1.00 38.05 C +ATOM 996 CG LEU A 222 -46.123 -6.776 -56.747 1.00 41.89 C +ATOM 997 CD1 LEU A 222 -44.733 -6.173 -56.845 1.00 48.51 C +ATOM 998 CD2 LEU A 222 -46.268 -7.598 -55.478 1.00 38.00 C +ATOM 999 N LYS A 223 -49.972 -7.206 -55.144 1.00 42.12 N +ATOM 1000 CA LYS A 223 -50.540 -7.372 -53.816 1.00 39.24 C +ATOM 1001 C LYS A 223 -50.783 -8.856 -53.586 1.00 42.15 C +ATOM 1002 O LYS A 223 -51.179 -9.575 -54.508 1.00 45.12 O +ATOM 1003 CB LYS A 223 -51.839 -6.574 -53.643 1.00 38.00 C +ATOM 1004 CG LYS A 223 -52.985 -6.990 -54.556 1.00 41.07 C +ATOM 1005 CD LYS A 223 -54.182 -6.076 -54.352 1.00 46.61 C +ATOM 1006 CE LYS A 223 -55.121 -6.097 -55.543 1.00 50.02 C +ATOM 1007 NZ LYS A 223 -56.244 -5.125 -55.379 1.00 54.14 N +ATOM 1008 N LEU A 224 -50.520 -9.307 -52.362 1.00 41.16 N +ATOM 1009 CA LEU A 224 -50.693 -10.695 -51.963 1.00 38.00 C +ATOM 1010 C LEU A 224 -51.668 -10.765 -50.802 1.00 39.72 C +ATOM 1011 O LEU A 224 -51.998 -9.755 -50.177 1.00 46.03 O +ATOM 1012 CB LEU A 224 -49.366 -11.329 -51.538 1.00 38.00 C +ATOM 1013 CG LEU A 224 -48.212 -11.147 -52.506 1.00 38.00 C +ATOM 1014 CD1 LEU A 224 -46.951 -11.765 -51.940 1.00 38.00 C +ATOM 1015 CD2 LEU A 224 -48.586 -11.762 -53.836 1.00 46.83 C +ATOM 1016 N VAL A 225 -52.142 -11.973 -50.520 1.00 38.58 N +ATOM 1017 CA VAL A 225 -53.006 -12.223 -49.374 1.00 40.65 C +ATOM 1018 C VAL A 225 -52.287 -13.207 -48.459 1.00 40.68 C +ATOM 1019 O VAL A 225 -52.012 -14.348 -48.852 1.00 38.54 O +ATOM 1020 CB VAL A 225 -54.387 -12.745 -49.789 1.00 38.00 C +ATOM 1021 CG1 VAL A 225 -54.251 -13.780 -50.874 1.00 38.08 C +ATOM 1022 CG2 VAL A 225 -55.092 -13.327 -48.581 1.00 41.98 C +ATOM 1023 N LEU A 226 -51.986 -12.767 -47.245 1.00 40.95 N +ATOM 1024 CA LEU A 226 -51.212 -13.552 -46.300 1.00 45.87 C +ATOM 1025 C LEU A 226 -52.117 -14.166 -45.234 1.00 49.95 C +ATOM 1026 O LEU A 226 -53.184 -13.635 -44.913 1.00 47.85 O +ATOM 1027 CB LEU A 226 -50.134 -12.681 -45.648 1.00 41.30 C +ATOM 1028 CG LEU A 226 -48.795 -12.516 -46.377 1.00 38.00 C +ATOM 1029 CD1 LEU A 226 -48.963 -12.421 -47.875 1.00 38.00 C +ATOM 1030 CD2 LEU A 226 -48.052 -11.303 -45.856 1.00 38.00 C +ATOM 1031 N ARG A 227 -51.678 -15.300 -44.692 1.00 48.62 N +ATOM 1032 CA ARG A 227 -52.372 -15.982 -43.610 1.00 51.95 C +ATOM 1033 C ARG A 227 -51.428 -16.148 -42.434 1.00 52.89 C +ATOM 1034 O ARG A 227 -50.245 -16.461 -42.607 1.00 49.16 O +ATOM 1035 CB ARG A 227 -52.895 -17.361 -44.018 1.00 57.49 C +ATOM 1036 CG ARG A 227 -53.613 -17.388 -45.340 1.00 70.27 C +ATOM 1037 CD ARG A 227 -54.639 -18.503 -45.386 1.00 62.13 C +ATOM 1038 NE ARG A 227 -55.715 -18.268 -44.431 1.00 47.11 N +ATOM 1039 CZ ARG A 227 -56.940 -18.754 -44.572 1.00 47.67 C +ATOM 1040 NH1 ARG A 227 -57.242 -19.487 -45.633 1.00 52.24 N +ATOM 1041 NH2 ARG A 227 -57.866 -18.488 -43.669 1.00 49.00 N +ATOM 1042 N PHE A 228 -51.952 -15.915 -41.243 1.00 51.35 N +ATOM 1043 CA PHE A 228 -51.174 -15.996 -40.024 1.00 46.55 C +ATOM 1044 C PHE A 228 -51.583 -17.222 -39.226 1.00 44.60 C +ATOM 1045 O PHE A 228 -52.569 -17.901 -39.529 1.00 45.40 O +ATOM 1046 CB PHE A 228 -51.361 -14.735 -39.189 1.00 53.62 C +ATOM 1047 CG PHE A 228 -51.197 -13.474 -39.966 1.00 49.32 C +ATOM 1048 CD1 PHE A 228 -49.935 -12.974 -40.248 1.00 44.42 C +ATOM 1049 CD2 PHE A 228 -52.307 -12.801 -40.438 1.00 45.47 C +ATOM 1050 CE1 PHE A 228 -49.789 -11.811 -40.965 1.00 42.87 C +ATOM 1051 CE2 PHE A 228 -52.171 -11.643 -41.159 1.00 46.91 C +ATOM 1052 CZ PHE A 228 -50.911 -11.145 -41.423 1.00 48.42 C +ATOM 1053 N SER A 229 -50.821 -17.467 -38.161 1.00 40.09 N +ATOM 1054 CA SER A 229 -51.026 -18.658 -37.354 1.00 38.45 C +ATOM 1055 C SER A 229 -52.400 -18.696 -36.699 1.00 38.16 C +ATOM 1056 O SER A 229 -52.879 -19.782 -36.364 1.00 49.38 O +ATOM 1057 CB SER A 229 -49.938 -18.743 -36.291 1.00 41.85 C +ATOM 1058 OG SER A 229 -49.940 -17.568 -35.506 1.00 49.24 O +ATOM 1059 N ASP A 230 -53.055 -17.555 -36.513 1.00 38.90 N +ATOM 1060 CA ASP A 230 -54.406 -17.577 -35.973 1.00 38.50 C +ATOM 1061 C ASP A 230 -55.461 -17.743 -37.061 1.00 42.13 C +ATOM 1062 O ASP A 230 -56.648 -17.535 -36.791 1.00 43.57 O +ATOM 1063 CB ASP A 230 -54.671 -16.320 -35.128 1.00 42.09 C +ATOM 1064 CG ASP A 230 -54.589 -15.028 -35.925 1.00 48.56 C +ATOM 1065 OD1 ASP A 230 -54.230 -15.072 -37.118 1.00 58.69 O +ATOM 1066 OD2 ASP A 230 -54.875 -13.957 -35.348 1.00 45.29 O +ATOM 1067 N PHE A 231 -55.050 -18.120 -38.274 1.00 40.37 N +ATOM 1068 CA PHE A 231 -55.860 -18.423 -39.450 1.00 46.70 C +ATOM 1069 C PHE A 231 -56.342 -17.163 -40.164 1.00 53.69 C +ATOM 1070 O PHE A 231 -56.869 -17.270 -41.271 1.00 60.88 O +ATOM 1071 CB PHE A 231 -57.080 -19.313 -39.134 1.00 49.43 C +ATOM 1072 CG PHE A 231 -57.676 -19.997 -40.336 1.00 56.47 C +ATOM 1073 CD1 PHE A 231 -56.994 -21.015 -40.981 1.00 57.10 C +ATOM 1074 CD2 PHE A 231 -58.936 -19.642 -40.801 1.00 62.77 C +ATOM 1075 CE1 PHE A 231 -57.550 -21.654 -42.082 1.00 60.19 C +ATOM 1076 CE2 PHE A 231 -59.500 -20.282 -41.899 1.00 56.94 C +ATOM 1077 CZ PHE A 231 -58.804 -21.286 -42.539 1.00 55.77 C +ATOM 1078 N GLY A 232 -56.184 -15.977 -39.582 1.00 53.87 N +ATOM 1079 CA GLY A 232 -56.673 -14.766 -40.209 1.00 57.21 C +ATOM 1080 C GLY A 232 -55.898 -14.385 -41.455 1.00 57.60 C +ATOM 1081 O GLY A 232 -54.797 -14.868 -41.726 1.00 56.59 O +ATOM 1082 N LYS A 233 -56.489 -13.478 -42.226 1.00 51.97 N +ATOM 1083 CA LYS A 233 -55.891 -13.018 -43.467 1.00 52.40 C +ATOM 1084 C LYS A 233 -55.733 -11.503 -43.456 1.00 52.71 C +ATOM 1085 O LYS A 233 -56.342 -10.787 -42.655 1.00 48.81 O +ATOM 1086 CB LYS A 233 -56.724 -13.444 -44.680 1.00 50.02 C +ATOM 1087 CG LYS A 233 -56.833 -14.931 -44.873 1.00 48.81 C +ATOM 1088 CD LYS A 233 -57.524 -15.242 -46.190 1.00 50.55 C +ATOM 1089 CE LYS A 233 -59.030 -15.285 -46.013 1.00 54.63 C +ATOM 1090 NZ LYS A 233 -59.716 -15.761 -47.236 1.00 62.22 N +ATOM 1091 N ALA A 234 -54.919 -11.024 -44.394 1.00 45.87 N +ATOM 1092 CA ALA A 234 -54.600 -9.612 -44.508 1.00 40.87 C +ATOM 1093 C ALA A 234 -54.045 -9.358 -45.900 1.00 42.56 C +ATOM 1094 O ALA A 234 -53.267 -10.162 -46.412 1.00 45.22 O +ATOM 1095 CB ALA A 234 -53.581 -9.189 -43.447 1.00 38.00 C +ATOM 1096 N MET A 235 -54.445 -8.238 -46.498 1.00 42.87 N +ATOM 1097 CA MET A 235 -54.008 -7.862 -47.836 1.00 38.00 C +ATOM 1098 C MET A 235 -52.681 -7.119 -47.738 1.00 38.00 C +ATOM 1099 O MET A 235 -52.602 -6.062 -47.103 1.00 38.00 O +ATOM 1100 CB MET A 235 -55.065 -7.001 -48.525 1.00 39.23 C +ATOM 1101 CG MET A 235 -54.792 -6.702 -49.998 1.00 51.83 C +ATOM 1102 SD MET A 235 -54.828 -8.154 -51.076 1.00 50.09 S +ATOM 1103 CE MET A 235 -56.512 -8.698 -50.828 1.00 54.29 C +ATOM 1104 N PHE A 236 -51.644 -7.680 -48.352 1.00 38.00 N +ATOM 1105 CA PHE A 236 -50.283 -7.167 -48.272 1.00 38.00 C +ATOM 1106 C PHE A 236 -49.984 -6.273 -49.472 1.00 40.05 C +ATOM 1107 O PHE A 236 -50.107 -6.709 -50.621 1.00 42.73 O +ATOM 1108 CB PHE A 236 -49.299 -8.332 -48.217 1.00 38.00 C +ATOM 1109 CG PHE A 236 -47.856 -7.924 -48.223 1.00 38.00 C +ATOM 1110 CD1 PHE A 236 -47.234 -7.518 -47.061 1.00 38.00 C +ATOM 1111 CD2 PHE A 236 -47.115 -7.971 -49.390 1.00 38.00 C +ATOM 1112 CE1 PHE A 236 -45.901 -7.160 -47.061 1.00 38.00 C +ATOM 1113 CE2 PHE A 236 -45.785 -7.611 -49.397 1.00 38.00 C +ATOM 1114 CZ PHE A 236 -45.176 -7.204 -48.229 1.00 38.00 C +ATOM 1115 N LYS A 237 -49.596 -5.028 -49.200 1.00 38.00 N +ATOM 1116 CA LYS A 237 -49.152 -4.072 -50.208 1.00 38.00 C +ATOM 1117 C LYS A 237 -47.705 -3.700 -49.912 1.00 38.00 C +ATOM 1118 O LYS A 237 -47.421 -3.164 -48.828 1.00 38.00 O +ATOM 1119 CB LYS A 237 -50.040 -2.830 -50.206 1.00 38.00 C +ATOM 1120 CG LYS A 237 -51.494 -3.089 -50.557 1.00 38.00 C +ATOM 1121 CD LYS A 237 -51.792 -2.718 -52.000 1.00 38.86 C +ATOM 1122 CE LYS A 237 -53.282 -2.841 -52.322 1.00 46.99 C +ATOM 1123 NZ LYS A 237 -54.169 -1.969 -51.495 1.00 45.33 N +ATOM 1124 N PRO A 238 -46.760 -3.985 -50.799 1.00 38.00 N +ATOM 1125 CA PRO A 238 -45.349 -3.716 -50.507 1.00 39.19 C +ATOM 1126 C PRO A 238 -44.976 -2.250 -50.706 1.00 41.74 C +ATOM 1127 O PRO A 238 -45.730 -1.445 -51.255 1.00 39.92 O +ATOM 1128 CB PRO A 238 -44.612 -4.609 -51.509 1.00 39.78 C +ATOM 1129 CG PRO A 238 -45.535 -4.668 -52.670 1.00 43.30 C +ATOM 1130 CD PRO A 238 -46.936 -4.651 -52.101 1.00 49.20 C +ATOM 1131 N MET A 239 -43.773 -1.921 -50.240 1.00 43.73 N +ATOM 1132 CA MET A 239 -43.231 -0.583 -50.421 1.00 42.28 C +ATOM 1133 C MET A 239 -42.880 -0.353 -51.884 1.00 46.41 C +ATOM 1134 O MET A 239 -42.102 -1.108 -52.474 1.00 47.26 O +ATOM 1135 CB MET A 239 -41.989 -0.402 -49.555 1.00 40.28 C +ATOM 1136 CG MET A 239 -41.343 0.951 -49.694 1.00 43.83 C +ATOM 1137 SD MET A 239 -39.981 1.185 -48.541 1.00 39.32 S +ATOM 1138 CE MET A 239 -38.718 0.164 -49.297 1.00 38.00 C +ATOM 1139 N ARG A 240 -43.390 0.739 -52.446 1.00 52.15 N +ATOM 1140 CA ARG A 240 -43.207 1.040 -53.855 1.00 47.22 C +ATOM 1141 C ARG A 240 -42.539 2.386 -54.090 1.00 50.89 C +ATOM 1142 O ARG A 240 -42.253 2.724 -55.244 1.00 46.55 O +ATOM 1143 CB ARG A 240 -44.563 1.008 -54.577 1.00 50.55 C +ATOM 1144 CG ARG A 240 -45.370 -0.263 -54.339 1.00 51.27 C +ATOM 1145 CD ARG A 240 -45.280 -1.192 -55.532 1.00 55.97 C +ATOM 1146 NE ARG A 240 -44.015 -1.029 -56.239 1.00 54.53 N +ATOM 1147 CZ ARG A 240 -43.702 -1.670 -57.358 1.00 55.13 C +ATOM 1148 NH1 ARG A 240 -44.564 -2.525 -57.888 1.00 53.88 N +ATOM 1149 NH2 ARG A 240 -42.530 -1.456 -57.943 1.00 53.58 N +ATOM 1150 N GLN A 241 -42.287 3.158 -53.033 1.00 52.27 N +ATOM 1151 CA GLN A 241 -41.698 4.486 -53.137 1.00 52.96 C +ATOM 1152 C GLN A 241 -41.124 4.882 -51.786 1.00 50.85 C +ATOM 1153 O GLN A 241 -41.609 4.446 -50.740 1.00 58.66 O +ATOM 1154 CB GLN A 241 -42.731 5.524 -53.584 1.00 54.51 C +ATOM 1155 CG GLN A 241 -42.688 5.861 -55.057 1.00 53.77 C +ATOM 1156 CD GLN A 241 -43.579 7.029 -55.388 1.00 49.83 C +ATOM 1157 OE1 GLN A 241 -44.596 7.258 -54.726 1.00 40.91 O +ATOM 1158 NE2 GLN A 241 -43.206 7.781 -56.415 1.00 56.03 N +ATOM 1159 N GLN A 242 -40.114 5.747 -51.824 1.00 53.57 N +ATOM 1160 CA GLN A 242 -39.511 6.290 -50.615 1.00 56.70 C +ATOM 1161 C GLN A 242 -40.507 7.202 -49.886 1.00 59.54 C +ATOM 1162 O GLN A 242 -41.633 7.432 -50.340 1.00 59.54 O +ATOM 1163 CB GLN A 242 -38.229 7.039 -50.969 1.00 58.28 C +ATOM 1164 CG GLN A 242 -37.161 6.155 -51.572 1.00 50.04 C +ATOM 1165 CD GLN A 242 -36.654 5.133 -50.588 1.00 49.44 C +ATOM 1166 OE1 GLN A 242 -36.661 5.366 -49.384 1.00 60.91 O +ATOM 1167 NE2 GLN A 242 -36.206 3.993 -51.092 1.00 57.62 N +ATOM 1168 N ARG A 243 -40.097 7.705 -48.714 1.00 54.66 N +ATOM 1169 CA ARG A 243 -40.965 8.591 -47.936 1.00 57.25 C +ATOM 1170 C ARG A 243 -41.027 9.990 -48.540 1.00 54.56 C +ATOM 1171 O ARG A 243 -42.115 10.546 -48.735 1.00 50.74 O +ATOM 1172 CB ARG A 243 -40.489 8.654 -46.483 1.00 48.63 C +ATOM 1173 CG ARG A 243 -40.663 7.353 -45.754 1.00 46.04 C +ATOM 1174 CD ARG A 243 -42.106 6.874 -45.848 1.00 43.15 C +ATOM 1175 NE ARG A 243 -42.195 5.432 -45.662 1.00 45.69 N +ATOM 1176 CZ ARG A 243 -42.182 4.826 -44.482 1.00 48.80 C +ATOM 1177 NH1 ARG A 243 -42.078 5.540 -43.371 1.00 45.67 N +ATOM 1178 NH2 ARG A 243 -42.262 3.503 -44.416 1.00 53.09 N +ATOM 1179 N ASP A 244 -39.869 10.563 -48.864 1.00 53.24 N +ATOM 1180 CA ASP A 244 -39.801 11.921 -49.384 1.00 48.09 C +ATOM 1181 C ASP A 244 -40.040 11.960 -50.888 1.00 46.22 C +ATOM 1182 O ASP A 244 -39.548 12.861 -51.565 1.00 51.16 O +ATOM 1183 CB ASP A 244 -38.439 12.542 -49.072 1.00 55.17 C +ATOM 1184 CG ASP A 244 -37.282 11.670 -49.541 1.00 67.09 C +ATOM 1185 OD1 ASP A 244 -37.025 11.613 -50.764 1.00 59.39 O +ATOM 1186 OD2 ASP A 244 -36.623 11.042 -48.683 1.00 76.69 O +ATOM 1187 N GLU A 245 -40.785 10.993 -51.416 1.00 49.08 N +ATOM 1188 CA GLU A 245 -41.042 10.909 -52.846 1.00 51.94 C +ATOM 1189 C GLU A 245 -42.513 11.169 -53.139 1.00 46.78 C +ATOM 1190 O GLU A 245 -43.396 10.666 -52.436 1.00 46.49 O +ATOM 1191 CB GLU A 245 -40.637 9.540 -53.404 1.00 51.88 C +ATOM 1192 CG GLU A 245 -39.147 9.383 -53.667 1.00 55.27 C +ATOM 1193 CD GLU A 245 -38.824 8.131 -54.465 1.00 60.40 C +ATOM 1194 OE1 GLU A 245 -39.762 7.386 -54.822 1.00 62.00 O +ATOM 1195 OE2 GLU A 245 -37.630 7.896 -54.746 1.00 66.82 O +ATOM 1196 N GLU A 246 -42.769 11.960 -54.174 1.00 41.55 N +ATOM 1197 CA GLU A 246 -44.119 12.266 -54.619 1.00 43.41 C +ATOM 1198 C GLU A 246 -44.404 11.566 -55.943 1.00 45.10 C +ATOM 1199 O GLU A 246 -43.490 11.112 -56.640 1.00 40.34 O +ATOM 1200 CB GLU A 246 -44.330 13.779 -54.773 1.00 47.74 C +ATOM 1201 CG GLU A 246 -43.859 14.619 -53.591 1.00 48.45 C +ATOM 1202 CD GLU A 246 -44.294 16.076 -53.693 1.00 50.58 C +ATOM 1203 OE1 GLU A 246 -45.460 16.337 -54.068 1.00 50.45 O +ATOM 1204 OE2 GLU A 246 -43.456 16.963 -53.423 1.00 47.96 O +ATOM 1205 N THR A 247 -45.698 11.460 -56.270 1.00 45.29 N +ATOM 1206 CA THR A 247 -46.092 11.069 -57.618 1.00 50.35 C +ATOM 1207 C THR A 247 -45.567 12.135 -58.567 1.00 59.17 C +ATOM 1208 O THR A 247 -45.990 13.295 -58.491 1.00 66.43 O +ATOM 1209 CB THR A 247 -47.612 10.925 -57.760 1.00 45.54 C +ATOM 1210 OG1 THR A 247 -48.106 11.862 -58.728 1.00 52.44 O +ATOM 1211 CG2 THR A 247 -48.302 11.167 -56.448 1.00 39.48 C +ATOM 1212 N PRO A 248 -44.633 11.792 -59.455 1.00 57.23 N +ATOM 1213 CA PRO A 248 -44.028 12.823 -60.303 1.00 65.55 C +ATOM 1214 C PRO A 248 -45.072 13.484 -61.188 1.00 68.95 C +ATOM 1215 O PRO A 248 -46.058 12.865 -61.591 1.00 60.03 O +ATOM 1216 CB PRO A 248 -42.994 12.049 -61.127 1.00 66.25 C +ATOM 1217 CG PRO A 248 -43.499 10.638 -61.130 1.00 63.30 C +ATOM 1218 CD PRO A 248 -44.182 10.436 -59.811 1.00 54.08 C +ATOM 1219 N VAL A 249 -44.869 14.779 -61.446 1.00 77.86 N +ATOM 1220 CA VAL A 249 -45.714 15.463 -62.410 1.00 66.33 C +ATOM 1221 C VAL A 249 -45.582 14.750 -63.749 1.00 63.05 C +ATOM 1222 O VAL A 249 -44.567 14.103 -64.034 1.00 60.99 O +ATOM 1223 CB VAL A 249 -45.345 16.951 -62.520 1.00 71.73 C +ATOM 1224 CG1 VAL A 249 -45.563 17.652 -61.178 1.00 75.79 C +ATOM 1225 CG2 VAL A 249 -43.899 17.098 -62.971 1.00 68.71 C +ATOM 1226 N ASP A 250 -46.632 14.857 -64.566 1.00 64.13 N +ATOM 1227 CA ASP A 250 -46.868 14.108 -65.809 1.00 66.22 C +ATOM 1228 C ASP A 250 -47.451 12.731 -65.521 1.00 62.91 C +ATOM 1229 O ASP A 250 -47.531 11.901 -66.436 1.00 62.15 O +ATOM 1230 CB ASP A 250 -45.623 13.923 -66.689 1.00 63.55 C +ATOM 1231 CG ASP A 250 -44.894 15.228 -66.970 1.00 61.64 C +ATOM 1232 OD1 ASP A 250 -45.572 16.264 -67.149 1.00 67.39 O +ATOM 1233 OD2 ASP A 250 -43.641 15.209 -67.018 1.00 40.77 O +ATOM 1234 N PHE A 251 -47.862 12.456 -64.289 1.00 58.64 N +ATOM 1235 CA PHE A 251 -48.457 11.177 -63.930 1.00 47.69 C +ATOM 1236 C PHE A 251 -49.942 11.383 -63.695 1.00 45.55 C +ATOM 1237 O PHE A 251 -50.335 12.125 -62.790 1.00 51.68 O +ATOM 1238 CB PHE A 251 -47.802 10.585 -62.685 1.00 56.18 C +ATOM 1239 CG PHE A 251 -46.860 9.459 -62.976 1.00 63.27 C +ATOM 1240 CD1 PHE A 251 -45.669 9.690 -63.641 1.00 70.21 C +ATOM 1241 CD2 PHE A 251 -47.163 8.169 -62.584 1.00 58.27 C +ATOM 1242 CE1 PHE A 251 -44.794 8.652 -63.905 1.00 64.01 C +ATOM 1243 CE2 PHE A 251 -46.298 7.131 -62.848 1.00 59.40 C +ATOM 1244 CZ PHE A 251 -45.111 7.373 -63.509 1.00 56.75 C +ATOM 1245 N PHE A 252 -50.761 10.741 -64.514 1.00 44.73 N +ATOM 1246 CA PHE A 252 -52.190 10.748 -64.276 1.00 51.94 C +ATOM 1247 C PHE A 252 -52.516 9.924 -63.030 1.00 47.44 C +ATOM 1248 O PHE A 252 -51.664 9.233 -62.463 1.00 49.85 O +ATOM 1249 CB PHE A 252 -52.927 10.211 -65.500 1.00 55.23 C +ATOM 1250 CG PHE A 252 -53.009 11.190 -66.631 1.00 57.11 C +ATOM 1251 CD1 PHE A 252 -53.995 12.163 -66.648 1.00 69.82 C +ATOM 1252 CD2 PHE A 252 -52.093 11.152 -67.666 1.00 52.56 C +ATOM 1253 CE1 PHE A 252 -54.077 13.073 -67.688 1.00 71.01 C +ATOM 1254 CE2 PHE A 252 -52.167 12.058 -68.709 1.00 63.00 C +ATOM 1255 CZ PHE A 252 -53.161 13.021 -68.721 1.00 68.17 C +ATOM 1256 N TYR A 253 -53.771 10.011 -62.592 1.00 38.00 N +ATOM 1257 CA TYR A 253 -54.165 9.280 -61.396 1.00 38.00 C +ATOM 1258 C TYR A 253 -54.094 7.771 -61.613 1.00 45.49 C +ATOM 1259 O TYR A 253 -53.609 7.042 -60.740 1.00 49.46 O +ATOM 1260 CB TYR A 253 -55.568 9.708 -60.962 1.00 43.39 C +ATOM 1261 CG TYR A 253 -56.534 9.918 -62.106 1.00 49.87 C +ATOM 1262 CD1 TYR A 253 -56.605 11.141 -62.761 1.00 53.33 C +ATOM 1263 CD2 TYR A 253 -57.398 8.910 -62.509 1.00 57.61 C +ATOM 1264 CE1 TYR A 253 -57.483 11.344 -63.806 1.00 56.57 C +ATOM 1265 CE2 TYR A 253 -58.285 9.107 -63.554 1.00 60.25 C +ATOM 1266 CZ TYR A 253 -58.321 10.326 -64.198 1.00 60.10 C +ATOM 1267 OH TYR A 253 -59.204 10.533 -65.233 1.00 63.20 O +ATOM 1268 N PHE A 254 -54.505 7.285 -62.793 1.00 52.30 N +ATOM 1269 CA PHE A 254 -54.584 5.841 -63.016 1.00 46.76 C +ATOM 1270 C PHE A 254 -53.221 5.174 -63.146 1.00 41.32 C +ATOM 1271 O PHE A 254 -53.150 3.942 -63.097 1.00 40.41 O +ATOM 1272 CB PHE A 254 -55.435 5.519 -64.258 1.00 45.32 C +ATOM 1273 CG PHE A 254 -55.187 6.427 -65.436 1.00 49.27 C +ATOM 1274 CD1 PHE A 254 -54.074 6.254 -66.245 1.00 48.75 C +ATOM 1275 CD2 PHE A 254 -56.095 7.423 -65.764 1.00 49.89 C +ATOM 1276 CE1 PHE A 254 -53.852 7.079 -67.335 1.00 49.83 C +ATOM 1277 CE2 PHE A 254 -55.880 8.252 -66.854 1.00 52.05 C +ATOM 1278 CZ PHE A 254 -54.760 8.078 -67.642 1.00 53.65 C +ATOM 1279 N ILE A 255 -52.140 5.938 -63.267 1.00 42.71 N +ATOM 1280 CA ILE A 255 -50.799 5.372 -63.287 1.00 48.14 C +ATOM 1281 C ILE A 255 -50.014 5.759 -62.043 1.00 51.83 C +ATOM 1282 O ILE A 255 -48.806 5.512 -61.975 1.00 54.78 O +ATOM 1283 CB ILE A 255 -50.029 5.768 -64.557 1.00 52.07 C +ATOM 1284 CG1 ILE A 255 -49.829 7.275 -64.605 1.00 59.46 C +ATOM 1285 CG2 ILE A 255 -50.775 5.322 -65.800 1.00 47.84 C +ATOM 1286 CD1 ILE A 255 -48.972 7.714 -65.759 1.00 65.87 C +ATOM 1287 N ASP A 256 -50.664 6.388 -61.066 1.00 48.01 N +ATOM 1288 CA ASP A 256 -50.006 6.701 -59.807 1.00 51.48 C +ATOM 1289 C ASP A 256 -49.635 5.406 -59.078 1.00 55.45 C +ATOM 1290 O ASP A 256 -50.163 4.326 -59.362 1.00 57.63 O +ATOM 1291 CB ASP A 256 -50.915 7.587 -58.948 1.00 51.77 C +ATOM 1292 CG ASP A 256 -50.148 8.410 -57.920 1.00 48.02 C +ATOM 1293 OD1 ASP A 256 -48.933 8.177 -57.748 1.00 49.98 O +ATOM 1294 OD2 ASP A 256 -50.755 9.322 -57.316 1.00 38.15 O +ATOM 1295 N PHE A 257 -48.719 5.525 -58.122 1.00 54.22 N +ATOM 1296 CA PHE A 257 -48.164 4.364 -57.437 1.00 53.35 C +ATOM 1297 C PHE A 257 -49.188 3.770 -56.464 1.00 60.09 C +ATOM 1298 O PHE A 257 -50.380 4.094 -56.477 1.00 55.60 O +ATOM 1299 CB PHE A 257 -46.879 4.743 -56.708 1.00 48.02 C +ATOM 1300 CG PHE A 257 -45.664 4.777 -57.579 1.00 53.92 C +ATOM 1301 CD1 PHE A 257 -44.903 3.639 -57.768 1.00 57.50 C +ATOM 1302 CD2 PHE A 257 -45.278 5.947 -58.203 1.00 65.65 C +ATOM 1303 CE1 PHE A 257 -43.772 3.667 -58.564 1.00 64.51 C +ATOM 1304 CE2 PHE A 257 -44.149 5.984 -59.004 1.00 64.37 C +ATOM 1305 CZ PHE A 257 -43.395 4.841 -59.184 1.00 62.30 C +ATOM 1306 N GLN A 258 -48.693 2.889 -55.580 1.00 59.29 N +ATOM 1307 CA GLN A 258 -49.488 2.119 -54.622 1.00 54.10 C +ATOM 1308 C GLN A 258 -48.690 2.125 -53.316 1.00 54.13 C +ATOM 1309 O GLN A 258 -47.951 1.185 -53.014 1.00 59.17 O +ATOM 1310 CB GLN A 258 -49.737 0.698 -55.132 1.00 60.08 C +ATOM 1311 CG GLN A 258 -51.068 0.087 -54.738 1.00 56.15 C +ATOM 1312 CD GLN A 258 -52.004 -0.063 -55.920 1.00 54.70 C +ATOM 1313 OE1 GLN A 258 -51.716 0.411 -57.020 1.00 52.18 O +ATOM 1314 NE2 GLN A 258 -53.129 -0.729 -55.701 1.00 57.21 N +ATOM 1315 N ARG A 259 -48.774 3.222 -52.568 1.00 50.83 N +ATOM 1316 CA ARG A 259 -47.917 3.382 -51.399 1.00 50.03 C +ATOM 1317 C ARG A 259 -48.449 2.583 -50.219 1.00 51.23 C +ATOM 1318 O ARG A 259 -49.624 2.702 -49.849 1.00 47.69 O +ATOM 1319 CB ARG A 259 -47.781 4.853 -51.016 1.00 51.73 C +ATOM 1320 CG ARG A 259 -48.452 5.806 -51.977 1.00 52.42 C +ATOM 1321 CD ARG A 259 -47.706 7.125 -52.075 1.00 43.28 C +ATOM 1322 NE ARG A 259 -47.347 7.398 -53.459 1.00 39.13 N +ATOM 1323 CZ ARG A 259 -48.219 7.790 -54.381 1.00 42.00 C +ATOM 1324 NH1 ARG A 259 -49.495 7.957 -54.055 1.00 41.92 N +ATOM 1325 NH2 ARG A 259 -47.816 8.013 -55.625 1.00 43.41 N +ATOM 1326 N HIS A 260 -47.564 1.795 -49.603 1.00 47.43 N +ATOM 1327 CA HIS A 260 -47.962 1.048 -48.420 1.00 41.99 C +ATOM 1328 C HIS A 260 -48.274 1.994 -47.276 1.00 42.19 C +ATOM 1329 O HIS A 260 -49.310 1.859 -46.617 1.00 48.59 O +ATOM 1330 CB HIS A 260 -46.865 0.057 -48.018 1.00 41.18 C +ATOM 1331 CG HIS A 260 -45.568 0.697 -47.610 1.00 45.48 C +ATOM 1332 ND1 HIS A 260 -44.986 1.732 -48.311 1.00 47.79 N +ATOM 1333 CD2 HIS A 260 -44.744 0.443 -46.565 1.00 46.21 C +ATOM 1334 CE1 HIS A 260 -43.859 2.085 -47.717 1.00 50.08 C +ATOM 1335 NE2 HIS A 260 -43.690 1.318 -46.655 1.00 45.90 N +ATOM 1336 N ASN A 261 -47.430 3.006 -47.083 1.00 40.28 N +ATOM 1337 CA ASN A 261 -47.614 3.916 -45.966 1.00 38.00 C +ATOM 1338 C ASN A 261 -48.916 4.683 -46.074 1.00 38.00 C +ATOM 1339 O ASN A 261 -49.439 5.142 -45.054 1.00 44.06 O +ATOM 1340 CB ASN A 261 -46.438 4.873 -45.894 1.00 38.00 C +ATOM 1341 CG ASN A 261 -46.306 5.688 -47.142 1.00 41.55 C +ATOM 1342 OD1 ASN A 261 -45.752 5.228 -48.141 1.00 49.23 O +ATOM 1343 ND2 ASN A 261 -46.827 6.903 -47.108 1.00 51.14 N +ATOM 1344 N ALA A 262 -49.473 4.804 -47.275 1.00 38.00 N +ATOM 1345 CA ALA A 262 -50.765 5.461 -47.377 1.00 38.00 C +ATOM 1346 C ALA A 262 -51.871 4.553 -46.865 1.00 38.00 C +ATOM 1347 O ALA A 262 -52.805 5.023 -46.211 1.00 38.00 O +ATOM 1348 CB ALA A 262 -51.036 5.884 -48.820 1.00 38.78 C +ATOM 1349 N GLU A 263 -51.766 3.244 -47.126 1.00 38.12 N +ATOM 1350 CA GLU A 263 -52.744 2.301 -46.587 1.00 43.17 C +ATOM 1351 C GLU A 263 -52.761 2.320 -45.067 1.00 41.10 C +ATOM 1352 O GLU A 263 -53.814 2.103 -44.456 1.00 40.28 O +ATOM 1353 CB GLU A 263 -52.469 0.884 -47.092 1.00 49.53 C +ATOM 1354 CG GLU A 263 -52.854 0.649 -48.546 1.00 49.52 C +ATOM 1355 CD GLU A 263 -54.336 0.326 -48.731 1.00 53.50 C +ATOM 1356 OE1 GLU A 263 -54.947 -0.283 -47.826 1.00 57.91 O +ATOM 1357 OE2 GLU A 263 -54.890 0.688 -49.787 1.00 52.52 O +ATOM 1358 N ILE A 264 -51.603 2.536 -44.444 1.00 38.78 N +ATOM 1359 CA ILE A 264 -51.537 2.651 -42.990 1.00 38.00 C +ATOM 1360 C ILE A 264 -52.170 3.955 -42.531 1.00 40.83 C +ATOM 1361 O ILE A 264 -53.118 3.966 -41.735 1.00 40.05 O +ATOM 1362 CB ILE A 264 -50.080 2.560 -42.516 1.00 38.00 C +ATOM 1363 CG1 ILE A 264 -49.397 1.357 -43.148 1.00 38.00 C +ATOM 1364 CG2 ILE A 264 -50.019 2.513 -41.018 1.00 38.00 C +ATOM 1365 CD1 ILE A 264 -47.920 1.333 -42.900 1.00 38.00 C +ATOM 1366 N ALA A 265 -51.651 5.075 -43.039 1.00 40.71 N +ATOM 1367 CA ALA A 265 -52.126 6.384 -42.614 1.00 40.46 C +ATOM 1368 C ALA A 265 -53.605 6.573 -42.909 1.00 38.00 C +ATOM 1369 O ALA A 265 -54.302 7.262 -42.157 1.00 38.00 O +ATOM 1370 CB ALA A 265 -51.299 7.476 -43.287 1.00 38.91 C +ATOM 1371 N ALA A 266 -54.109 5.953 -43.976 1.00 38.00 N +ATOM 1372 CA ALA A 266 -55.537 6.036 -44.244 1.00 38.00 C +ATOM 1373 C ALA A 266 -56.335 5.404 -43.124 1.00 38.00 C +ATOM 1374 O ALA A 266 -57.463 5.826 -42.848 1.00 39.23 O +ATOM 1375 CB ALA A 266 -55.879 5.357 -45.567 1.00 43.38 C +ATOM 1376 N PHE A 267 -55.766 4.400 -42.462 1.00 38.00 N +ATOM 1377 CA PHE A 267 -56.466 3.787 -41.344 1.00 41.07 C +ATOM 1378 C PHE A 267 -56.481 4.713 -40.138 1.00 45.20 C +ATOM 1379 O PHE A 267 -57.536 4.940 -39.535 1.00 49.76 O +ATOM 1380 CB PHE A 267 -55.832 2.443 -40.993 1.00 38.58 C +ATOM 1381 CG PHE A 267 -56.272 1.901 -39.669 1.00 39.09 C +ATOM 1382 CD1 PHE A 267 -57.617 1.678 -39.413 1.00 39.67 C +ATOM 1383 CD2 PHE A 267 -55.344 1.597 -38.689 1.00 38.00 C +ATOM 1384 CE1 PHE A 267 -58.031 1.182 -38.194 1.00 38.00 C +ATOM 1385 CE2 PHE A 267 -55.751 1.092 -37.470 1.00 39.19 C +ATOM 1386 CZ PHE A 267 -57.097 0.884 -37.223 1.00 40.90 C +ATOM 1387 N HIS A 268 -55.328 5.291 -39.796 1.00 41.30 N +ATOM 1388 CA HIS A 268 -55.273 6.167 -38.632 1.00 39.38 C +ATOM 1389 C HIS A 268 -56.170 7.379 -38.807 1.00 42.80 C +ATOM 1390 O HIS A 268 -56.873 7.776 -37.870 1.00 44.27 O +ATOM 1391 CB HIS A 268 -53.835 6.583 -38.377 1.00 38.00 C +ATOM 1392 CG HIS A 268 -52.976 5.448 -37.944 1.00 38.00 C +ATOM 1393 ND1 HIS A 268 -52.525 5.313 -36.651 1.00 44.78 N +ATOM 1394 CD2 HIS A 268 -52.533 4.362 -38.615 1.00 40.02 C +ATOM 1395 CE1 HIS A 268 -51.811 4.205 -36.551 1.00 49.18 C +ATOM 1396 NE2 HIS A 268 -51.803 3.608 -37.729 1.00 48.38 N +ATOM 1397 N LEU A 269 -56.204 7.946 -40.015 1.00 43.38 N +ATOM 1398 CA LEU A 269 -57.116 9.053 -40.283 1.00 44.94 C +ATOM 1399 C LEU A 269 -58.566 8.617 -40.128 1.00 41.92 C +ATOM 1400 O LEU A 269 -59.401 9.372 -39.616 1.00 41.19 O +ATOM 1401 CB LEU A 269 -56.867 9.599 -41.688 1.00 39.61 C +ATOM 1402 CG LEU A 269 -56.852 11.115 -41.876 1.00 38.00 C +ATOM 1403 CD1 LEU A 269 -56.790 11.437 -43.349 1.00 38.00 C +ATOM 1404 CD2 LEU A 269 -58.058 11.766 -41.243 1.00 38.00 C +ATOM 1405 N ASP A 270 -58.882 7.394 -40.554 1.00 41.52 N +ATOM 1406 CA ASP A 270 -60.217 6.859 -40.328 1.00 40.68 C +ATOM 1407 C ASP A 270 -60.519 6.760 -38.841 1.00 41.59 C +ATOM 1408 O ASP A 270 -61.648 7.015 -38.406 1.00 38.41 O +ATOM 1409 CB ASP A 270 -60.350 5.495 -41.000 1.00 41.94 C +ATOM 1410 CG ASP A 270 -61.724 4.887 -40.812 1.00 52.10 C +ATOM 1411 OD1 ASP A 270 -62.669 5.621 -40.445 1.00 48.70 O +ATOM 1412 OD2 ASP A 270 -61.859 3.666 -41.031 1.00 55.82 O +ATOM 1413 N ARG A 271 -59.523 6.369 -38.049 1.00 42.74 N +ATOM 1414 CA ARG A 271 -59.740 6.221 -36.618 1.00 41.56 C +ATOM 1415 C ARG A 271 -59.891 7.577 -35.941 1.00 41.95 C +ATOM 1416 O ARG A 271 -60.736 7.743 -35.053 1.00 45.18 O +ATOM 1417 CB ARG A 271 -58.587 5.424 -36.008 1.00 38.00 C +ATOM 1418 CG ARG A 271 -58.908 4.835 -34.661 1.00 38.00 C +ATOM 1419 CD ARG A 271 -57.917 3.765 -34.248 1.00 38.20 C +ATOM 1420 NE ARG A 271 -56.532 4.162 -34.483 1.00 44.11 N +ATOM 1421 CZ ARG A 271 -55.485 3.355 -34.320 1.00 47.50 C +ATOM 1422 NH1 ARG A 271 -55.659 2.102 -33.917 1.00 45.16 N +ATOM 1423 NH2 ARG A 271 -54.259 3.802 -34.555 1.00 44.51 N +ATOM 1424 N ILE A 272 -59.114 8.568 -36.380 1.00 38.84 N +ATOM 1425 CA ILE A 272 -59.150 9.883 -35.750 1.00 38.00 C +ATOM 1426 C ILE A 272 -60.460 10.597 -36.069 1.00 38.00 C +ATOM 1427 O ILE A 272 -61.021 11.297 -35.218 1.00 43.62 O +ATOM 1428 CB ILE A 272 -57.922 10.709 -36.180 1.00 38.00 C +ATOM 1429 CG1 ILE A 272 -56.770 10.555 -35.181 1.00 38.00 C +ATOM 1430 CG2 ILE A 272 -58.276 12.175 -36.324 1.00 40.07 C +ATOM 1431 CD1 ILE A 272 -56.179 9.165 -35.101 1.00 38.55 C +ATOM 1432 N LEU A 273 -60.968 10.437 -37.295 1.00 38.00 N +ATOM 1433 CA LEU A 273 -62.227 11.073 -37.681 1.00 38.51 C +ATOM 1434 C LEU A 273 -63.450 10.400 -37.079 1.00 39.54 C +ATOM 1435 O LEU A 273 -64.555 10.941 -37.204 1.00 38.00 O +ATOM 1436 CB LEU A 273 -62.387 11.090 -39.199 1.00 38.09 C +ATOM 1437 CG LEU A 273 -61.507 12.026 -40.017 1.00 38.00 C +ATOM 1438 CD1 LEU A 273 -61.753 11.763 -41.485 1.00 42.30 C +ATOM 1439 CD2 LEU A 273 -61.803 13.469 -39.674 1.00 38.00 C +ATOM 1440 N ASP A 274 -63.290 9.232 -36.465 1.00 40.43 N +ATOM 1441 CA ASP A 274 -64.417 8.435 -35.994 1.00 43.73 C +ATOM 1442 C ASP A 274 -65.389 8.121 -37.132 1.00 49.54 C +ATOM 1443 O ASP A 274 -66.608 8.106 -36.939 1.00 48.01 O +ATOM 1444 CB ASP A 274 -65.137 9.115 -34.829 1.00 45.69 C +ATOM 1445 CG ASP A 274 -65.978 8.150 -34.035 1.00 51.08 C +ATOM 1446 OD1 ASP A 274 -65.454 7.068 -33.696 1.00 47.34 O +ATOM 1447 OD2 ASP A 274 -67.154 8.467 -33.756 1.00 57.45 O +ATOM 1448 N PHE A 275 -64.854 7.962 -38.347 1.00 47.55 N +ATOM 1449 CA PHE A 275 -65.635 7.402 -39.446 1.00 48.88 C +ATOM 1450 C PHE A 275 -65.786 5.896 -39.294 1.00 49.62 C +ATOM 1451 O PHE A 275 -66.877 5.350 -39.506 1.00 46.08 O +ATOM 1452 CB PHE A 275 -64.979 7.734 -40.780 1.00 54.24 C +ATOM 1453 CG PHE A 275 -65.334 9.087 -41.307 1.00 57.46 C +ATOM 1454 CD1 PHE A 275 -66.412 9.787 -40.792 1.00 57.87 C +ATOM 1455 CD2 PHE A 275 -64.580 9.665 -42.311 1.00 49.35 C +ATOM 1456 CE1 PHE A 275 -66.736 11.034 -41.282 1.00 59.09 C +ATOM 1457 CE2 PHE A 275 -64.896 10.909 -42.802 1.00 54.07 C +ATOM 1458 CZ PHE A 275 -65.977 11.597 -42.287 1.00 64.01 C +ATOM 1459 N ARG A 276 -64.691 5.212 -38.946 1.00 47.72 N +ATOM 1460 CA ARG A 276 -64.705 3.781 -38.640 1.00 47.08 C +ATOM 1461 C ARG A 276 -65.227 2.974 -39.825 1.00 50.31 C +ATOM 1462 O ARG A 276 -66.249 2.290 -39.745 1.00 53.16 O +ATOM 1463 CB ARG A 276 -65.528 3.533 -37.367 1.00 49.56 C +ATOM 1464 CG ARG A 276 -64.691 3.223 -36.131 1.00 46.40 C +ATOM 1465 CD ARG A 276 -65.316 3.683 -34.821 1.00 44.32 C +ATOM 1466 NE ARG A 276 -66.721 3.312 -34.684 1.00 49.16 N +ATOM 1467 CZ ARG A 276 -67.691 4.222 -34.703 1.00 52.81 C +ATOM 1468 NH1 ARG A 276 -67.360 5.505 -34.816 1.00 51.23 N +ATOM 1469 NH2 ARG A 276 -68.970 3.873 -34.585 1.00 63.28 N +ATOM 1470 N ARG A 277 -64.496 3.077 -40.941 1.00 50.42 N +ATOM 1471 CA ARG A 277 -64.923 2.506 -42.217 1.00 46.66 C +ATOM 1472 C ARG A 277 -63.824 1.797 -42.998 1.00 43.99 C +ATOM 1473 O ARG A 277 -64.146 0.960 -43.846 1.00 47.87 O +ATOM 1474 CB ARG A 277 -65.542 3.593 -43.096 1.00 45.10 C +ATOM 1475 CG ARG A 277 -66.843 4.111 -42.533 1.00 47.45 C +ATOM 1476 CD ARG A 277 -67.300 5.348 -43.243 1.00 54.31 C +ATOM 1477 NE ARG A 277 -68.048 6.231 -42.356 1.00 58.48 N +ATOM 1478 CZ ARG A 277 -68.709 7.300 -42.780 1.00 65.83 C +ATOM 1479 NH1 ARG A 277 -68.711 7.594 -44.075 1.00 77.45 N +ATOM 1480 NH2 ARG A 277 -69.367 8.067 -41.921 1.00 55.61 N +ATOM 1481 N VAL A 278 -62.553 2.110 -42.794 1.00 41.50 N +ATOM 1482 CA VAL A 278 -61.503 1.365 -43.480 1.00 43.87 C +ATOM 1483 C VAL A 278 -61.039 0.225 -42.580 1.00 47.16 C +ATOM 1484 O VAL A 278 -61.163 0.317 -41.349 1.00 44.20 O +ATOM 1485 CB VAL A 278 -60.339 2.281 -43.885 1.00 46.37 C +ATOM 1486 CG1 VAL A 278 -60.862 3.657 -44.196 1.00 52.75 C +ATOM 1487 CG2 VAL A 278 -59.303 2.340 -42.788 1.00 45.77 C +ATOM 1488 N PRO A 279 -60.538 -0.879 -43.138 1.00 47.33 N +ATOM 1489 CA PRO A 279 -60.080 -1.972 -42.291 1.00 41.20 C +ATOM 1490 C PRO A 279 -58.781 -1.606 -41.594 1.00 38.16 C +ATOM 1491 O PRO A 279 -57.926 -0.912 -42.169 1.00 38.00 O +ATOM 1492 CB PRO A 279 -59.868 -3.127 -43.285 1.00 42.66 C +ATOM 1493 CG PRO A 279 -60.622 -2.739 -44.499 1.00 47.47 C +ATOM 1494 CD PRO A 279 -60.520 -1.253 -44.559 1.00 47.05 C +ATOM 1495 N PRO A 280 -58.570 -2.099 -40.378 1.00 38.00 N +ATOM 1496 CA PRO A 280 -57.318 -1.818 -39.671 1.00 38.00 C +ATOM 1497 C PRO A 280 -56.116 -2.251 -40.491 1.00 38.00 C +ATOM 1498 O PRO A 280 -56.146 -3.270 -41.179 1.00 42.57 O +ATOM 1499 CB PRO A 280 -57.452 -2.639 -38.385 1.00 38.00 C +ATOM 1500 CG PRO A 280 -58.932 -2.765 -38.189 1.00 38.00 C +ATOM 1501 CD PRO A 280 -59.516 -2.868 -39.553 1.00 38.00 C +ATOM 1502 N THR A 281 -55.065 -1.441 -40.440 1.00 38.00 N +ATOM 1503 CA THR A 281 -53.888 -1.668 -41.262 1.00 38.00 C +ATOM 1504 C THR A 281 -52.641 -1.331 -40.461 1.00 38.00 C +ATOM 1505 O THR A 281 -52.591 -0.287 -39.806 1.00 41.01 O +ATOM 1506 CB THR A 281 -53.956 -0.821 -42.537 1.00 38.00 C +ATOM 1507 OG1 THR A 281 -55.172 -1.109 -43.243 1.00 38.00 O +ATOM 1508 CG2 THR A 281 -52.779 -1.120 -43.435 1.00 43.52 C +ATOM 1509 N VAL A 282 -51.655 -2.223 -40.484 1.00 38.00 N +ATOM 1510 CA VAL A 282 -50.391 -1.993 -39.802 1.00 38.00 C +ATOM 1511 C VAL A 282 -49.268 -2.121 -40.819 1.00 38.00 C +ATOM 1512 O VAL A 282 -49.426 -2.712 -41.889 1.00 38.00 O +ATOM 1513 CB VAL A 282 -50.163 -2.955 -38.614 1.00 38.00 C +ATOM 1514 CG1 VAL A 282 -51.444 -3.634 -38.238 1.00 38.00 C +ATOM 1515 CG2 VAL A 282 -49.115 -4.001 -38.942 1.00 38.00 C +ATOM 1516 N GLY A 283 -48.131 -1.527 -40.483 1.00 41.85 N +ATOM 1517 CA GLY A 283 -46.908 -1.711 -41.235 1.00 39.33 C +ATOM 1518 C GLY A 283 -46.039 -2.771 -40.586 1.00 44.97 C +ATOM 1519 O GLY A 283 -46.034 -2.928 -39.369 1.00 52.66 O +ATOM 1520 N ARG A 284 -45.306 -3.510 -41.414 1.00 42.18 N +ATOM 1521 CA ARG A 284 -44.488 -4.606 -40.919 1.00 40.97 C +ATOM 1522 C ARG A 284 -43.327 -4.836 -41.871 1.00 39.94 C +ATOM 1523 O ARG A 284 -43.479 -4.708 -43.087 1.00 40.34 O +ATOM 1524 CB ARG A 284 -45.320 -5.884 -40.770 1.00 38.00 C +ATOM 1525 CG ARG A 284 -44.517 -7.153 -40.559 1.00 41.36 C +ATOM 1526 CD ARG A 284 -45.444 -8.312 -40.248 1.00 43.71 C +ATOM 1527 NE ARG A 284 -44.726 -9.567 -40.061 1.00 40.00 N +ATOM 1528 CZ ARG A 284 -45.315 -10.714 -39.746 1.00 43.20 C +ATOM 1529 NH1 ARG A 284 -46.631 -10.765 -39.581 1.00 38.00 N +ATOM 1530 NH2 ARG A 284 -44.590 -11.813 -39.598 1.00 50.63 N +ATOM 1531 N ILE A 285 -42.167 -5.143 -41.311 1.00 39.07 N +ATOM 1532 CA ILE A 285 -41.014 -5.557 -42.096 1.00 38.00 C +ATOM 1533 C ILE A 285 -41.105 -7.059 -42.322 1.00 43.15 C +ATOM 1534 O ILE A 285 -41.293 -7.826 -41.371 1.00 55.09 O +ATOM 1535 CB ILE A 285 -39.706 -5.192 -41.388 1.00 38.16 C +ATOM 1536 CG1 ILE A 285 -39.649 -3.689 -41.121 1.00 41.68 C +ATOM 1537 CG2 ILE A 285 -38.522 -5.685 -42.207 1.00 43.01 C +ATOM 1538 CD1 ILE A 285 -38.404 -3.254 -40.384 1.00 47.42 C +ATOM 1539 N VAL A 286 -40.982 -7.482 -43.577 1.00 38.83 N +ATOM 1540 CA VAL A 286 -41.213 -8.867 -43.971 1.00 41.21 C +ATOM 1541 C VAL A 286 -39.912 -9.454 -44.514 1.00 43.94 C +ATOM 1542 O VAL A 286 -39.181 -8.774 -45.242 1.00 44.24 O +ATOM 1543 CB VAL A 286 -42.349 -8.971 -45.009 1.00 38.00 C +ATOM 1544 CG1 VAL A 286 -42.630 -10.419 -45.345 1.00 38.00 C +ATOM 1545 CG2 VAL A 286 -43.616 -8.302 -44.490 1.00 38.00 C +ATOM 1546 N ASN A 287 -39.580 -10.677 -44.082 1.00 48.11 N +ATOM 1547 CA ASN A 287 -38.542 -11.495 -44.722 1.00 45.39 C +ATOM 1548 C ASN A 287 -39.201 -12.198 -45.904 1.00 47.72 C +ATOM 1549 O ASN A 287 -39.841 -13.241 -45.742 1.00 46.80 O +ATOM 1550 CB ASN A 287 -37.926 -12.491 -43.736 1.00 45.35 C +ATOM 1551 CG ASN A 287 -36.699 -13.220 -44.305 1.00 42.24 C +ATOM 1552 OD1 ASN A 287 -36.597 -13.429 -45.507 1.00 44.45 O +ATOM 1553 ND2 ASN A 287 -35.767 -13.603 -43.433 1.00 38.00 N +ATOM 1554 N VAL A 288 -39.036 -11.624 -47.102 1.00 53.35 N +ATOM 1555 CA VAL A 288 -39.765 -12.078 -48.285 1.00 52.35 C +ATOM 1556 C VAL A 288 -39.460 -13.526 -48.633 1.00 52.90 C +ATOM 1557 O VAL A 288 -40.280 -14.198 -49.267 1.00 51.19 O +ATOM 1558 CB VAL A 288 -39.465 -11.158 -49.487 1.00 44.75 C +ATOM 1559 CG1 VAL A 288 -40.054 -9.786 -49.257 1.00 44.58 C +ATOM 1560 CG2 VAL A 288 -37.967 -11.065 -49.720 1.00 40.84 C +ATOM 1561 N THR A 289 -38.311 -14.040 -48.210 1.00 48.93 N +ATOM 1562 CA THR A 289 -38.037 -15.447 -48.455 1.00 46.89 C +ATOM 1563 C THR A 289 -38.754 -16.324 -47.436 1.00 52.08 C +ATOM 1564 O THR A 289 -39.524 -17.215 -47.809 1.00 50.53 O +ATOM 1565 CB THR A 289 -36.531 -15.699 -48.425 1.00 44.22 C +ATOM 1566 OG1 THR A 289 -35.896 -14.901 -49.429 1.00 39.27 O +ATOM 1567 CG2 THR A 289 -36.235 -17.165 -48.685 1.00 50.14 C +ATOM 1568 N LYS A 290 -38.549 -16.053 -46.142 1.00 53.71 N +ATOM 1569 CA LYS A 290 -39.086 -16.923 -45.100 1.00 53.53 C +ATOM 1570 C LYS A 290 -40.585 -16.726 -44.882 1.00 51.66 C +ATOM 1571 O LYS A 290 -41.276 -17.667 -44.472 1.00 52.14 O +ATOM 1572 CB LYS A 290 -38.326 -16.708 -43.784 1.00 47.03 C +ATOM 1573 CG LYS A 290 -38.735 -17.684 -42.677 1.00 45.90 C +ATOM 1574 CD LYS A 290 -38.059 -17.400 -41.344 1.00 38.00 C +ATOM 1575 CE LYS A 290 -38.634 -16.159 -40.683 1.00 46.13 C +ATOM 1576 NZ LYS A 290 -37.843 -15.710 -39.502 1.00 38.00 N +ATOM 1577 N GLU A 291 -41.105 -15.528 -45.138 1.00 44.74 N +ATOM 1578 CA GLU A 291 -42.485 -15.206 -44.812 1.00 41.92 C +ATOM 1579 C GLU A 291 -43.387 -15.074 -46.029 1.00 39.34 C +ATOM 1580 O GLU A 291 -44.586 -14.835 -45.859 1.00 39.07 O +ATOM 1581 CB GLU A 291 -42.540 -13.923 -43.974 1.00 44.53 C +ATOM 1582 CG GLU A 291 -42.284 -14.165 -42.493 1.00 47.35 C +ATOM 1583 CD GLU A 291 -41.874 -12.913 -41.753 1.00 43.08 C +ATOM 1584 OE1 GLU A 291 -41.529 -11.917 -42.413 1.00 45.91 O +ATOM 1585 OE2 GLU A 291 -41.894 -12.921 -40.508 1.00 51.20 O +ATOM 1586 N ILE A 292 -42.852 -15.199 -47.245 1.00 41.56 N +ATOM 1587 CA ILE A 292 -43.680 -15.158 -48.450 1.00 48.18 C +ATOM 1588 C ILE A 292 -43.375 -16.342 -49.359 1.00 47.04 C +ATOM 1589 O ILE A 292 -44.267 -17.130 -49.699 1.00 44.87 O +ATOM 1590 CB ILE A 292 -43.490 -13.847 -49.229 1.00 44.22 C +ATOM 1591 CG1 ILE A 292 -43.927 -12.648 -48.392 1.00 42.25 C +ATOM 1592 CG2 ILE A 292 -44.303 -13.896 -50.509 1.00 39.58 C +ATOM 1593 CD1 ILE A 292 -43.739 -11.330 -49.105 1.00 38.00 C +ATOM 1594 N LEU A 293 -42.121 -16.441 -49.802 1.00 43.54 N +ATOM 1595 CA LEU A 293 -41.758 -17.463 -50.776 1.00 41.70 C +ATOM 1596 C LEU A 293 -41.833 -18.856 -50.168 1.00 48.00 C +ATOM 1597 O LEU A 293 -42.404 -19.774 -50.765 1.00 51.31 O +ATOM 1598 CB LEU A 293 -40.358 -17.187 -51.323 1.00 43.12 C +ATOM 1599 CG LEU A 293 -39.784 -18.256 -52.250 1.00 42.24 C +ATOM 1600 CD1 LEU A 293 -40.704 -18.450 -53.437 1.00 45.15 C +ATOM 1601 CD2 LEU A 293 -38.384 -17.866 -52.709 1.00 42.72 C +ATOM 1602 N GLU A 294 -41.275 -19.034 -48.974 1.00 49.55 N +ATOM 1603 CA GLU A 294 -41.212 -20.358 -48.370 1.00 47.24 C +ATOM 1604 C GLU A 294 -42.545 -20.828 -47.810 1.00 43.42 C +ATOM 1605 O GLU A 294 -42.608 -21.937 -47.274 1.00 56.85 O +ATOM 1606 CB GLU A 294 -40.150 -20.387 -47.269 1.00 47.45 C +ATOM 1607 CG GLU A 294 -38.729 -20.324 -47.800 1.00 52.05 C +ATOM 1608 CD GLU A 294 -37.687 -20.447 -46.703 1.00 59.27 C +ATOM 1609 OE1 GLU A 294 -38.042 -20.867 -45.575 1.00 55.99 O +ATOM 1610 OE2 GLU A 294 -36.509 -20.132 -46.976 1.00 58.41 O +ATOM 1611 N VAL A 295 -43.607 -20.037 -47.929 1.00 38.00 N +ATOM 1612 CA VAL A 295 -44.918 -20.429 -47.435 1.00 44.78 C +ATOM 1613 C VAL A 295 -45.969 -20.464 -48.528 1.00 47.29 C +ATOM 1614 O VAL A 295 -47.116 -20.837 -48.256 1.00 47.95 O +ATOM 1615 CB VAL A 295 -45.376 -19.514 -46.281 1.00 43.56 C +ATOM 1616 CG1 VAL A 295 -45.240 -20.236 -44.958 1.00 46.14 C +ATOM 1617 CG2 VAL A 295 -44.551 -18.258 -46.268 1.00 44.54 C +ATOM 1618 N THR A 296 -45.623 -20.086 -49.753 1.00 47.71 N +ATOM 1619 CA THR A 296 -46.594 -20.076 -50.836 1.00 49.01 C +ATOM 1620 C THR A 296 -46.665 -21.429 -51.533 1.00 52.23 C +ATOM 1621 O THR A 296 -45.641 -22.038 -51.856 1.00 53.88 O +ATOM 1622 CB THR A 296 -46.265 -18.979 -51.852 1.00 46.29 C +ATOM 1623 OG1 THR A 296 -47.226 -19.018 -52.911 1.00 51.63 O +ATOM 1624 CG2 THR A 296 -44.875 -19.158 -52.428 1.00 45.35 C +ATOM 1625 N LYS A 297 -47.893 -21.888 -51.769 1.00 57.05 N +ATOM 1626 CA LYS A 297 -48.151 -23.100 -52.533 1.00 64.85 C +ATOM 1627 C LYS A 297 -48.484 -22.819 -53.992 1.00 59.04 C +ATOM 1628 O LYS A 297 -48.718 -23.763 -54.754 1.00 55.50 O +ATOM 1629 CB LYS A 297 -49.285 -23.906 -51.884 1.00 72.77 C +ATOM 1630 CG LYS A 297 -48.999 -24.363 -50.457 1.00 80.50 C +ATOM 1631 CD LYS A 297 -47.848 -25.368 -50.449 1.00 76.61 C +ATOM 1632 CE LYS A 297 -47.543 -25.887 -49.057 1.00 79.05 C +ATOM 1633 NZ LYS A 297 -46.510 -26.962 -49.114 1.00 66.79 N +ATOM 1634 N ASN A 298 -48.509 -21.549 -54.396 1.00 63.34 N +ATOM 1635 CA ASN A 298 -48.876 -21.174 -55.756 1.00 57.60 C +ATOM 1636 C ASN A 298 -47.649 -21.284 -56.652 1.00 52.47 C +ATOM 1637 O ASN A 298 -46.628 -20.632 -56.407 1.00 44.03 O +ATOM 1638 CB ASN A 298 -49.455 -19.760 -55.779 1.00 47.19 C +ATOM 1639 CG ASN A 298 -50.058 -19.393 -57.118 1.00 42.45 C +ATOM 1640 OD1 ASN A 298 -49.339 -19.068 -58.063 1.00 43.13 O +ATOM 1641 ND2 ASN A 298 -51.386 -19.443 -57.207 1.00 38.00 N +ATOM 1642 N GLU A 299 -47.760 -22.112 -57.694 1.00 55.04 N +ATOM 1643 CA GLU A 299 -46.616 -22.398 -58.552 1.00 54.89 C +ATOM 1644 C GLU A 299 -46.200 -21.177 -59.366 1.00 54.97 C +ATOM 1645 O GLU A 299 -45.023 -21.042 -59.724 1.00 48.63 O +ATOM 1646 CB GLU A 299 -46.952 -23.587 -59.449 1.00 49.51 C +ATOM 1647 CG GLU A 299 -47.686 -24.690 -58.689 1.00 53.76 C +ATOM 1648 CD GLU A 299 -46.807 -25.888 -58.351 1.00 55.74 C +ATOM 1649 OE1 GLU A 299 -45.618 -25.701 -57.997 1.00 46.31 O +ATOM 1650 OE2 GLU A 299 -47.318 -27.025 -58.436 1.00 55.36 O +ATOM 1651 N ILE A 300 -47.136 -20.269 -59.644 1.00 55.09 N +ATOM 1652 CA ILE A 300 -46.789 -19.044 -60.354 1.00 47.54 C +ATOM 1653 C ILE A 300 -45.986 -18.125 -59.451 1.00 49.97 C +ATOM 1654 O ILE A 300 -44.951 -17.578 -59.850 1.00 47.51 O +ATOM 1655 CB ILE A 300 -48.059 -18.336 -60.848 1.00 38.00 C +ATOM 1656 CG1 ILE A 300 -49.062 -19.346 -61.378 1.00 38.00 C +ATOM 1657 CG2 ILE A 300 -47.713 -17.329 -61.912 1.00 41.22 C +ATOM 1658 CD1 ILE A 300 -50.353 -18.719 -61.789 1.00 38.00 C +ATOM 1659 N LEU A 301 -46.447 -17.957 -58.210 1.00 47.39 N +ATOM 1660 CA LEU A 301 -45.802 -17.021 -57.302 1.00 48.85 C +ATOM 1661 C LEU A 301 -44.354 -17.411 -57.042 1.00 52.69 C +ATOM 1662 O LEU A 301 -43.492 -16.538 -56.890 1.00 50.00 O +ATOM 1663 CB LEU A 301 -46.595 -16.947 -55.997 1.00 51.61 C +ATOM 1664 CG LEU A 301 -46.334 -15.760 -55.070 1.00 50.33 C +ATOM 1665 CD1 LEU A 301 -46.459 -14.455 -55.828 1.00 41.92 C +ATOM 1666 CD2 LEU A 301 -47.299 -15.788 -53.899 1.00 50.20 C +ATOM 1667 N GLN A 302 -44.055 -18.710 -57.025 1.00 54.69 N +ATOM 1668 CA GLN A 302 -42.666 -19.123 -56.903 1.00 55.43 C +ATOM 1669 C GLN A 302 -41.859 -18.749 -58.136 1.00 51.68 C +ATOM 1670 O GLN A 302 -40.643 -18.559 -58.035 1.00 50.29 O +ATOM 1671 CB GLN A 302 -42.575 -20.631 -56.663 1.00 57.16 C +ATOM 1672 CG GLN A 302 -43.244 -21.105 -55.387 1.00 60.56 C +ATOM 1673 CD GLN A 302 -43.352 -22.613 -55.318 1.00 65.05 C +ATOM 1674 OE1 GLN A 302 -44.049 -23.237 -56.120 1.00 63.37 O +ATOM 1675 NE2 GLN A 302 -42.650 -23.211 -54.362 1.00 73.75 N +ATOM 1676 N SER A 303 -42.516 -18.583 -59.281 1.00 49.57 N +ATOM 1677 CA SER A 303 -41.807 -18.331 -60.526 1.00 54.59 C +ATOM 1678 C SER A 303 -41.353 -16.887 -60.667 1.00 54.83 C +ATOM 1679 O SER A 303 -40.447 -16.612 -61.464 1.00 54.30 O +ATOM 1680 CB SER A 303 -42.703 -18.687 -61.709 1.00 58.88 C +ATOM 1681 OG SER A 303 -43.645 -17.650 -61.933 1.00 50.68 O +ATOM 1682 N VAL A 304 -41.945 -15.965 -59.903 1.00 51.97 N +ATOM 1683 CA VAL A 304 -41.632 -14.548 -60.028 1.00 46.51 C +ATOM 1684 C VAL A 304 -40.572 -14.095 -59.038 1.00 41.27 C +ATOM 1685 O VAL A 304 -40.252 -12.903 -58.988 1.00 42.98 O +ATOM 1686 CB VAL A 304 -42.906 -13.693 -59.873 1.00 42.03 C +ATOM 1687 CG1 VAL A 304 -43.964 -14.133 -60.874 1.00 43.57 C +ATOM 1688 CG2 VAL A 304 -43.429 -13.771 -58.458 1.00 41.29 C +ATOM 1689 N PHE A 305 -40.006 -15.008 -58.262 1.00 44.26 N +ATOM 1690 CA PHE A 305 -38.941 -14.680 -57.326 1.00 47.77 C +ATOM 1691 C PHE A 305 -37.600 -14.996 -57.971 1.00 47.02 C +ATOM 1692 O PHE A 305 -37.379 -16.119 -58.434 1.00 57.85 O +ATOM 1693 CB PHE A 305 -39.108 -15.448 -56.013 1.00 52.19 C +ATOM 1694 CG PHE A 305 -40.072 -14.804 -55.047 1.00 43.34 C +ATOM 1695 CD1 PHE A 305 -41.427 -15.085 -55.102 1.00 39.74 C +ATOM 1696 CD2 PHE A 305 -39.617 -13.918 -54.083 1.00 38.41 C +ATOM 1697 CE1 PHE A 305 -42.308 -14.492 -54.221 1.00 38.00 C +ATOM 1698 CE2 PHE A 305 -40.493 -13.324 -53.198 1.00 38.00 C +ATOM 1699 CZ PHE A 305 -41.840 -13.613 -53.267 1.00 38.00 C +ATOM 1700 N PHE A 306 -36.718 -14.003 -58.020 1.00 40.51 N +ATOM 1701 CA PHE A 306 -35.388 -14.185 -58.577 1.00 45.82 C +ATOM 1702 C PHE A 306 -34.398 -13.454 -57.685 1.00 41.80 C +ATOM 1703 O PHE A 306 -34.749 -12.944 -56.618 1.00 42.14 O +ATOM 1704 CB PHE A 306 -35.324 -13.709 -60.035 1.00 60.91 C +ATOM 1705 CG PHE A 306 -35.602 -12.239 -60.216 1.00 62.23 C +ATOM 1706 CD1 PHE A 306 -36.898 -11.786 -60.422 1.00 55.65 C +ATOM 1707 CD2 PHE A 306 -34.569 -11.311 -60.178 1.00 53.49 C +ATOM 1708 CE1 PHE A 306 -37.158 -10.441 -60.591 1.00 52.16 C +ATOM 1709 CE2 PHE A 306 -34.826 -9.963 -60.344 1.00 54.27 C +ATOM 1710 CZ PHE A 306 -36.122 -9.530 -60.553 1.00 56.25 C +ATOM 1711 N VAL A 307 -33.142 -13.421 -58.114 1.00 41.83 N +ATOM 1712 CA VAL A 307 -32.076 -12.769 -57.367 1.00 46.99 C +ATOM 1713 C VAL A 307 -31.426 -11.740 -58.282 1.00 50.09 C +ATOM 1714 O VAL A 307 -31.166 -12.023 -59.457 1.00 46.81 O +ATOM 1715 CB VAL A 307 -31.049 -13.785 -56.832 1.00 39.50 C +ATOM 1716 CG1 VAL A 307 -29.945 -13.077 -56.072 1.00 39.36 C +ATOM 1717 CG2 VAL A 307 -31.729 -14.793 -55.931 1.00 38.00 C +ATOM 1718 N SER A 308 -31.198 -10.543 -57.750 1.00 53.83 N +ATOM 1719 CA SER A 308 -30.647 -9.433 -58.503 1.00 46.48 C +ATOM 1720 C SER A 308 -29.143 -9.587 -58.660 1.00 46.21 C +ATOM 1721 O SER A 308 -28.510 -10.353 -57.933 1.00 52.83 O +ATOM 1722 CB SER A 308 -30.946 -8.121 -57.783 1.00 48.53 C +ATOM 1723 OG SER A 308 -32.325 -7.818 -57.831 1.00 59.68 O +ATOM 1724 N PRO A 309 -28.539 -8.856 -59.599 1.00 49.54 N +ATOM 1725 CA PRO A 309 -27.069 -8.768 -59.618 1.00 52.07 C +ATOM 1726 C PRO A 309 -26.484 -8.232 -58.323 1.00 60.29 C +ATOM 1727 O PRO A 309 -25.286 -8.426 -58.074 1.00 58.83 O +ATOM 1728 CB PRO A 309 -26.787 -7.832 -60.798 1.00 53.22 C +ATOM 1729 CG PRO A 309 -27.971 -8.008 -61.696 1.00 54.94 C +ATOM 1730 CD PRO A 309 -29.147 -8.233 -60.787 1.00 49.54 C +ATOM 1731 N ALA A 310 -27.284 -7.545 -57.503 1.00 58.07 N +ATOM 1732 CA ALA A 310 -26.884 -7.100 -56.175 1.00 53.00 C +ATOM 1733 C ALA A 310 -27.140 -8.149 -55.107 1.00 54.19 C +ATOM 1734 O ALA A 310 -26.916 -7.874 -53.924 1.00 62.98 O +ATOM 1735 CB ALA A 310 -27.622 -5.810 -55.807 1.00 53.16 C +ATOM 1736 N SER A 311 -27.589 -9.341 -55.503 1.00 50.45 N +ATOM 1737 CA SER A 311 -27.831 -10.460 -54.592 1.00 45.52 C +ATOM 1738 C SER A 311 -28.961 -10.145 -53.609 1.00 41.75 C +ATOM 1739 O SER A 311 -28.836 -10.331 -52.399 1.00 44.41 O +ATOM 1740 CB SER A 311 -26.547 -10.834 -53.848 1.00 45.08 C +ATOM 1741 OG SER A 311 -25.458 -10.947 -54.747 1.00 41.11 O +ATOM 1742 N ASN A 312 -30.090 -9.698 -54.148 1.00 40.80 N +ATOM 1743 CA ASN A 312 -31.279 -9.393 -53.365 1.00 45.26 C +ATOM 1744 C ASN A 312 -32.435 -10.262 -53.837 1.00 40.64 C +ATOM 1745 O ASN A 312 -32.575 -10.527 -55.033 1.00 41.08 O +ATOM 1746 CB ASN A 312 -31.680 -7.907 -53.475 1.00 54.11 C +ATOM 1747 CG ASN A 312 -30.655 -6.959 -52.860 1.00 56.02 C +ATOM 1748 OD1 ASN A 312 -29.907 -7.329 -51.956 1.00 52.81 O +ATOM 1749 ND2 ASN A 312 -30.611 -5.727 -53.369 1.00 57.73 N +ATOM 1750 N VAL A 313 -33.242 -10.729 -52.892 1.00 39.29 N +ATOM 1751 CA VAL A 313 -34.447 -11.482 -53.218 1.00 38.43 C +ATOM 1752 C VAL A 313 -35.504 -10.494 -53.689 1.00 47.11 C +ATOM 1753 O VAL A 313 -35.924 -9.617 -52.927 1.00 55.24 O +ATOM 1754 CB VAL A 313 -34.946 -12.285 -52.010 1.00 38.00 C +ATOM 1755 CG1 VAL A 313 -36.268 -12.957 -52.327 1.00 38.00 C +ATOM 1756 CG2 VAL A 313 -33.910 -13.307 -51.592 1.00 38.00 C +ATOM 1757 N CYS A 314 -35.912 -10.609 -54.950 1.00 46.84 N +ATOM 1758 CA CYS A 314 -36.898 -9.717 -55.539 1.00 41.40 C +ATOM 1759 C CYS A 314 -38.077 -10.511 -56.086 1.00 42.24 C +ATOM 1760 O CYS A 314 -37.958 -11.691 -56.424 1.00 44.35 O +ATOM 1761 CB CYS A 314 -36.283 -8.890 -56.662 1.00 45.27 C +ATOM 1762 SG CYS A 314 -34.677 -8.196 -56.275 1.00 85.00 S +ATOM 1763 N PHE A 315 -39.215 -9.836 -56.203 1.00 43.12 N +ATOM 1764 CA PHE A 315 -40.380 -10.403 -56.865 1.00 44.16 C +ATOM 1765 C PHE A 315 -41.153 -9.266 -57.518 1.00 52.08 C +ATOM 1766 O PHE A 315 -40.845 -8.089 -57.322 1.00 58.03 O +ATOM 1767 CB PHE A 315 -41.261 -11.208 -55.900 1.00 44.99 C +ATOM 1768 CG PHE A 315 -42.001 -10.371 -54.889 1.00 48.39 C +ATOM 1769 CD1 PHE A 315 -41.335 -9.457 -54.087 1.00 43.69 C +ATOM 1770 CD2 PHE A 315 -43.375 -10.494 -54.755 1.00 45.59 C +ATOM 1771 CE1 PHE A 315 -42.025 -8.692 -53.168 1.00 44.20 C +ATOM 1772 CE2 PHE A 315 -44.069 -9.732 -53.839 1.00 42.43 C +ATOM 1773 CZ PHE A 315 -43.393 -8.829 -53.046 1.00 46.19 C +ATOM 1774 N PHE A 316 -42.151 -9.625 -58.323 1.00 45.01 N +ATOM 1775 CA PHE A 316 -42.811 -8.646 -59.177 1.00 38.76 C +ATOM 1776 C PHE A 316 -44.216 -9.121 -59.508 1.00 38.00 C +ATOM 1777 O PHE A 316 -44.573 -10.277 -59.271 1.00 41.84 O +ATOM 1778 CB PHE A 316 -42.015 -8.408 -60.466 1.00 41.11 C +ATOM 1779 CG PHE A 316 -41.769 -9.662 -61.270 1.00 44.73 C +ATOM 1780 CD1 PHE A 316 -42.713 -10.123 -62.180 1.00 44.29 C +ATOM 1781 CD2 PHE A 316 -40.592 -10.378 -61.116 1.00 46.32 C +ATOM 1782 CE1 PHE A 316 -42.490 -11.274 -62.916 1.00 39.37 C +ATOM 1783 CE2 PHE A 316 -40.364 -11.530 -61.850 1.00 44.85 C +ATOM 1784 CZ PHE A 316 -41.314 -11.976 -62.752 1.00 43.49 C +ATOM 1785 N ALA A 317 -45.017 -8.200 -60.034 1.00 38.00 N +ATOM 1786 CA ALA A 317 -46.300 -8.563 -60.620 1.00 42.14 C +ATOM 1787 C ALA A 317 -46.083 -9.060 -62.044 1.00 49.25 C +ATOM 1788 O ALA A 317 -45.340 -8.444 -62.816 1.00 49.70 O +ATOM 1789 CB ALA A 317 -47.257 -7.374 -60.609 1.00 44.58 C +ATOM 1790 N LYS A 318 -46.723 -10.182 -62.386 1.00 59.45 N +ATOM 1791 CA LYS A 318 -46.444 -10.846 -63.660 1.00 56.19 C +ATOM 1792 C LYS A 318 -46.761 -9.944 -64.846 1.00 57.57 C +ATOM 1793 O LYS A 318 -45.922 -9.753 -65.734 1.00 60.17 O +ATOM 1794 CB LYS A 318 -47.246 -12.147 -63.758 1.00 66.79 C +ATOM 1795 CG LYS A 318 -46.912 -13.027 -64.971 1.00 74.26 C +ATOM 1796 CD LYS A 318 -45.694 -13.909 -64.725 1.00 77.88 C +ATOM 1797 CE LYS A 318 -45.413 -14.835 -65.904 1.00 64.97 C +ATOM 1798 NZ LYS A 318 -44.226 -15.700 -65.647 1.00 75.26 N +ATOM 1799 N CYS A 319 -47.960 -9.350 -64.866 1.00 55.31 N +ATOM 1800 CA CYS A 319 -48.354 -8.573 -66.042 1.00 56.17 C +ATOM 1801 C CYS A 319 -47.585 -7.261 -66.147 1.00 49.38 C +ATOM 1802 O CYS A 319 -47.000 -7.000 -67.212 1.00 50.66 O +ATOM 1803 CB CYS A 319 -49.874 -8.370 -66.048 1.00 57.55 C +ATOM 1804 SG CYS A 319 -50.536 -7.405 -67.435 1.00 69.37 S +ATOM 1805 N PRO A 320 -47.517 -6.412 -65.117 1.00 47.56 N +ATOM 1806 CA PRO A 320 -46.753 -5.167 -65.272 1.00 48.54 C +ATOM 1807 C PRO A 320 -45.290 -5.381 -65.598 1.00 49.11 C +ATOM 1808 O PRO A 320 -44.707 -4.538 -66.288 1.00 62.39 O +ATOM 1809 CB PRO A 320 -46.931 -4.472 -63.918 1.00 51.84 C +ATOM 1810 CG PRO A 320 -48.206 -4.977 -63.435 1.00 60.17 C +ATOM 1811 CD PRO A 320 -48.272 -6.412 -63.855 1.00 55.08 C +ATOM 1812 N TYR A 321 -44.657 -6.449 -65.110 1.00 42.42 N +ATOM 1813 CA TYR A 321 -43.267 -6.669 -65.497 1.00 45.30 C +ATOM 1814 C TYR A 321 -43.157 -6.976 -66.984 1.00 48.35 C +ATOM 1815 O TYR A 321 -42.237 -6.498 -67.655 1.00 50.51 O +ATOM 1816 CB TYR A 321 -42.636 -7.791 -64.680 1.00 43.71 C +ATOM 1817 CG TYR A 321 -41.116 -7.803 -64.719 1.00 39.46 C +ATOM 1818 CD1 TYR A 321 -40.394 -6.723 -65.215 1.00 46.71 C +ATOM 1819 CD2 TYR A 321 -40.407 -8.909 -64.286 1.00 49.92 C +ATOM 1820 CE1 TYR A 321 -39.001 -6.744 -65.252 1.00 60.40 C +ATOM 1821 CE2 TYR A 321 -39.023 -8.941 -64.321 1.00 61.46 C +ATOM 1822 CZ TYR A 321 -38.321 -7.859 -64.802 1.00 63.81 C +ATOM 1823 OH TYR A 321 -36.940 -7.908 -64.827 1.00 56.34 O +ATOM 1824 N MET A 322 -44.081 -7.773 -67.520 1.00 47.42 N +ATOM 1825 CA MET A 322 -44.028 -8.108 -68.940 1.00 59.87 C +ATOM 1826 C MET A 322 -44.160 -6.862 -69.806 1.00 55.27 C +ATOM 1827 O MET A 322 -43.384 -6.659 -70.746 1.00 64.58 O +ATOM 1828 CB MET A 322 -45.120 -9.122 -69.279 1.00 66.32 C +ATOM 1829 CG MET A 322 -45.393 -9.282 -70.770 1.00 62.34 C +ATOM 1830 SD MET A 322 -46.272 -10.810 -71.141 1.00 91.89 S +ATOM 1831 CE MET A 322 -47.349 -10.964 -69.714 1.00 65.23 C +ATOM 1832 N CYS A 323 -45.113 -5.995 -69.483 1.00 46.22 N +ATOM 1833 CA CYS A 323 -45.273 -4.771 -70.251 1.00 50.03 C +ATOM 1834 C CYS A 323 -44.229 -3.716 -69.908 1.00 56.18 C +ATOM 1835 O CYS A 323 -44.238 -2.646 -70.522 1.00 66.42 O +ATOM 1836 CB CYS A 323 -46.681 -4.207 -70.048 1.00 53.69 C +ATOM 1837 SG CYS A 323 -48.026 -5.216 -70.714 1.00 61.08 S +ATOM 1838 N LYS A 324 -43.327 -3.998 -68.964 1.00 53.83 N +ATOM 1839 CA LYS A 324 -42.271 -3.064 -68.558 1.00 55.48 C +ATOM 1840 C LYS A 324 -42.853 -1.720 -68.117 1.00 53.44 C +ATOM 1841 O LYS A 324 -42.249 -0.661 -68.309 1.00 51.91 O +ATOM 1842 CB LYS A 324 -41.245 -2.882 -69.679 1.00 55.49 C +ATOM 1843 CG LYS A 324 -40.688 -4.205 -70.187 1.00 55.28 C +ATOM 1844 CD LYS A 324 -39.865 -4.908 -69.114 1.00 63.93 C +ATOM 1845 CE LYS A 324 -39.643 -6.382 -69.441 1.00 58.88 C +ATOM 1846 NZ LYS A 324 -38.501 -6.965 -68.673 1.00 55.75 N +ATOM 1847 N THR A 325 -44.031 -1.771 -67.496 1.00 49.78 N +ATOM 1848 CA THR A 325 -44.650 -0.584 -66.928 1.00 53.79 C +ATOM 1849 C THR A 325 -44.183 -0.316 -65.503 1.00 54.90 C +ATOM 1850 O THR A 325 -44.140 0.843 -65.077 1.00 50.94 O +ATOM 1851 CB THR A 325 -46.182 -0.714 -66.966 1.00 51.38 C +ATOM 1852 OG1 THR A 325 -46.737 -0.309 -65.708 1.00 66.76 O +ATOM 1853 CG2 THR A 325 -46.604 -2.131 -67.261 1.00 42.06 C +ATOM 1854 N GLU A 326 -43.792 -1.351 -64.766 1.00 52.76 N +ATOM 1855 CA GLU A 326 -43.234 -1.167 -63.436 1.00 52.94 C +ATOM 1856 C GLU A 326 -42.002 -2.047 -63.291 1.00 52.31 C +ATOM 1857 O GLU A 326 -41.663 -2.831 -64.182 1.00 50.65 O +ATOM 1858 CB GLU A 326 -44.258 -1.487 -62.345 1.00 49.95 C +ATOM 1859 CG GLU A 326 -44.333 -2.950 -62.008 1.00 48.37 C +ATOM 1860 CD GLU A 326 -45.240 -3.229 -60.836 1.00 55.29 C +ATOM 1861 OE1 GLU A 326 -46.270 -2.534 -60.698 1.00 56.89 O +ATOM 1862 OE2 GLU A 326 -44.907 -4.132 -60.037 1.00 50.55 O +ATOM 1863 N TYR A 327 -41.307 -1.888 -62.167 1.00 53.79 N +ATOM 1864 CA TYR A 327 -40.104 -2.658 -61.895 1.00 54.10 C +ATOM 1865 C TYR A 327 -40.425 -3.751 -60.882 1.00 51.22 C +ATOM 1866 O TYR A 327 -41.589 -4.011 -60.556 1.00 47.94 O +ATOM 1867 CB TYR A 327 -38.998 -1.738 -61.379 1.00 60.01 C +ATOM 1868 CG TYR A 327 -38.670 -0.587 -62.299 1.00 62.48 C +ATOM 1869 CD1 TYR A 327 -38.736 -0.727 -63.677 1.00 72.21 C +ATOM 1870 CD2 TYR A 327 -38.323 0.655 -61.783 1.00 60.93 C +ATOM 1871 CE1 TYR A 327 -38.441 0.331 -64.518 1.00 68.41 C +ATOM 1872 CE2 TYR A 327 -38.031 1.717 -62.616 1.00 64.62 C +ATOM 1873 CZ TYR A 327 -38.091 1.550 -63.980 1.00 62.04 C +ATOM 1874 OH TYR A 327 -37.803 2.610 -64.807 1.00 60.97 O +ATOM 1875 N ALA A 328 -39.383 -4.360 -60.330 1.00 40.12 N +ATOM 1876 CA ALA A 328 -39.563 -5.340 -59.278 1.00 38.00 C +ATOM 1877 C ALA A 328 -39.431 -4.669 -57.920 1.00 45.82 C +ATOM 1878 O ALA A 328 -39.087 -3.492 -57.807 1.00 55.65 O +ATOM 1879 CB ALA A 328 -38.555 -6.480 -59.420 1.00 42.71 C +ATOM 1880 N VAL A 329 -39.704 -5.450 -56.882 1.00 44.79 N +ATOM 1881 CA VAL A 329 -39.654 -5.004 -55.496 1.00 38.00 C +ATOM 1882 C VAL A 329 -38.653 -5.902 -54.798 1.00 38.00 C +ATOM 1883 O VAL A 329 -38.894 -7.105 -54.652 1.00 49.49 O +ATOM 1884 CB VAL A 329 -41.024 -5.074 -54.810 1.00 38.00 C +ATOM 1885 CG1 VAL A 329 -40.909 -4.606 -53.392 1.00 48.76 C +ATOM 1886 CG2 VAL A 329 -42.049 -4.235 -55.555 1.00 38.00 C +ATOM 1887 N CYS A 330 -37.500 -5.350 -54.444 1.00 38.00 N +ATOM 1888 CA CYS A 330 -36.430 -6.122 -53.826 1.00 53.18 C +ATOM 1889 C CYS A 330 -36.329 -5.877 -52.324 1.00 51.62 C +ATOM 1890 O CYS A 330 -36.603 -4.781 -51.830 1.00 55.39 O +ATOM 1891 CB CYS A 330 -35.085 -5.808 -54.472 1.00 61.32 C +ATOM 1892 SG CYS A 330 -34.999 -6.192 -56.222 1.00 72.27 S +ATOM 1893 N GLY A 331 -35.930 -6.923 -51.601 1.00 41.92 N +ATOM 1894 CA GLY A 331 -35.467 -6.764 -50.242 1.00 46.95 C +ATOM 1895 C GLY A 331 -34.019 -6.309 -50.190 1.00 52.63 C +ATOM 1896 O GLY A 331 -33.330 -6.193 -51.203 1.00 49.78 O +ATOM 1897 N LYS A 332 -33.539 -6.102 -48.964 1.00 58.78 N +ATOM 1898 CA LYS A 332 -32.173 -5.645 -48.702 1.00 61.08 C +ATOM 1899 C LYS A 332 -31.519 -6.544 -47.656 1.00 59.89 C +ATOM 1900 O LYS A 332 -31.390 -6.168 -46.484 1.00 62.39 O +ATOM 1901 CB LYS A 332 -32.158 -4.185 -48.242 1.00 67.82 C +ATOM 1902 CG LYS A 332 -31.603 -3.185 -49.259 1.00 68.97 C +ATOM 1903 CD LYS A 332 -32.561 -2.965 -50.426 1.00 80.84 C +ATOM 1904 CE LYS A 332 -32.089 -1.837 -51.341 1.00 82.38 C +ATOM 1905 NZ LYS A 332 -30.793 -2.160 -52.000 1.00 78.07 N +ATOM 1906 N PRO A 333 -31.147 -7.776 -48.036 1.00 53.46 N +ATOM 1907 CA PRO A 333 -31.445 -8.412 -49.320 1.00 46.40 C +ATOM 1908 C PRO A 333 -32.753 -9.190 -49.226 1.00 46.15 C +ATOM 1909 O PRO A 333 -33.377 -9.454 -50.251 1.00 47.14 O +ATOM 1910 CB PRO A 333 -30.240 -9.328 -49.555 1.00 41.17 C +ATOM 1911 CG PRO A 333 -29.635 -9.553 -48.205 1.00 45.91 C +ATOM 1912 CD PRO A 333 -30.276 -8.621 -47.204 1.00 54.77 C +ATOM 1913 N HIS A 334 -33.163 -9.530 -47.999 1.00 45.67 N +ATOM 1914 CA HIS A 334 -34.432 -10.196 -47.744 1.00 47.41 C +ATOM 1915 C HIS A 334 -35.487 -9.288 -47.128 1.00 47.75 C +ATOM 1916 O HIS A 334 -36.680 -9.571 -47.274 1.00 47.29 O +ATOM 1917 CB HIS A 334 -34.238 -11.398 -46.803 1.00 46.61 C +ATOM 1918 CG HIS A 334 -33.309 -12.447 -47.327 1.00 40.19 C +ATOM 1919 ND1 HIS A 334 -33.746 -13.534 -48.053 1.00 38.00 N +ATOM 1920 CD2 HIS A 334 -31.969 -12.591 -47.206 1.00 39.87 C +ATOM 1921 CE1 HIS A 334 -32.714 -14.294 -48.371 1.00 38.00 C +ATOM 1922 NE2 HIS A 334 -31.624 -13.744 -47.870 1.00 41.08 N +ATOM 1923 N LEU A 335 -35.083 -8.216 -46.453 1.00 46.48 N +ATOM 1924 CA LEU A 335 -36.011 -7.386 -45.694 1.00 46.94 C +ATOM 1925 C LEU A 335 -36.732 -6.395 -46.601 1.00 49.98 C +ATOM 1926 O LEU A 335 -36.095 -5.630 -47.330 1.00 54.75 O +ATOM 1927 CB LEU A 335 -35.264 -6.632 -44.595 1.00 49.65 C +ATOM 1928 CG LEU A 335 -34.752 -7.467 -43.424 1.00 45.22 C +ATOM 1929 CD1 LEU A 335 -35.814 -8.487 -43.034 1.00 38.00 C +ATOM 1930 CD2 LEU A 335 -33.403 -8.120 -43.747 1.00 44.47 C +ATOM 1931 N LEU A 336 -38.064 -6.407 -46.545 1.00 47.39 N +ATOM 1932 CA LEU A 336 -38.910 -5.481 -47.288 1.00 42.38 C +ATOM 1933 C LEU A 336 -40.108 -5.107 -46.432 1.00 40.70 C +ATOM 1934 O LEU A 336 -40.743 -5.985 -45.842 1.00 50.89 O +ATOM 1935 CB LEU A 336 -39.401 -6.099 -48.598 1.00 48.81 C +ATOM 1936 CG LEU A 336 -40.542 -5.343 -49.279 1.00 47.59 C +ATOM 1937 CD1 LEU A 336 -40.049 -4.045 -49.894 1.00 48.31 C +ATOM 1938 CD2 LEU A 336 -41.225 -6.216 -50.309 1.00 44.10 C +ATOM 1939 N GLU A 337 -40.450 -3.823 -46.394 1.00 38.00 N +ATOM 1940 CA GLU A 337 -41.560 -3.379 -45.562 1.00 42.41 C +ATOM 1941 C GLU A 337 -42.832 -3.272 -46.394 1.00 38.00 C +ATOM 1942 O GLU A 337 -42.790 -2.976 -47.588 1.00 38.00 O +ATOM 1943 CB GLU A 337 -41.270 -2.033 -44.885 1.00 51.92 C +ATOM 1944 CG GLU A 337 -41.122 -0.857 -45.837 1.00 51.39 C +ATOM 1945 CD GLU A 337 -40.984 0.483 -45.119 1.00 45.74 C +ATOM 1946 OE1 GLU A 337 -39.967 0.701 -44.421 1.00 44.30 O +ATOM 1947 OE2 GLU A 337 -41.913 1.311 -45.242 1.00 38.00 O +ATOM 1948 N GLY A 338 -43.965 -3.551 -45.754 1.00 38.00 N +ATOM 1949 CA GLY A 338 -45.245 -3.504 -46.426 1.00 38.00 C +ATOM 1950 C GLY A 338 -46.354 -3.156 -45.459 1.00 38.00 C +ATOM 1951 O GLY A 338 -46.120 -2.903 -44.276 1.00 38.00 O +ATOM 1952 N SER A 339 -47.578 -3.145 -45.978 1.00 38.00 N +ATOM 1953 CA SER A 339 -48.758 -2.785 -45.203 1.00 38.00 C +ATOM 1954 C SER A 339 -49.781 -3.903 -45.299 1.00 38.00 C +ATOM 1955 O SER A 339 -50.254 -4.220 -46.394 1.00 38.00 O +ATOM 1956 CB SER A 339 -49.360 -1.475 -45.708 1.00 41.01 C +ATOM 1957 OG SER A 339 -49.943 -1.648 -46.988 1.00 40.82 O +ATOM 1958 N LEU A 340 -50.144 -4.476 -44.159 1.00 38.88 N +ATOM 1959 CA LEU A 340 -51.147 -5.531 -44.102 1.00 38.00 C +ATOM 1960 C LEU A 340 -52.484 -4.920 -43.703 1.00 38.00 C +ATOM 1961 O LEU A 340 -52.593 -4.304 -42.639 1.00 38.06 O +ATOM 1962 CB LEU A 340 -50.740 -6.617 -43.107 1.00 38.00 C +ATOM 1963 CG LEU A 340 -49.371 -7.246 -43.350 1.00 38.00 C +ATOM 1964 CD1 LEU A 340 -48.366 -6.817 -42.295 1.00 38.00 C +ATOM 1965 CD2 LEU A 340 -49.490 -8.741 -43.407 1.00 43.26 C +ATOM 1966 N SER A 341 -53.495 -5.098 -44.544 1.00 38.00 N +ATOM 1967 CA SER A 341 -54.829 -4.580 -44.279 1.00 38.00 C +ATOM 1968 C SER A 341 -55.719 -5.748 -43.883 1.00 38.00 C +ATOM 1969 O SER A 341 -55.857 -6.705 -44.648 1.00 40.79 O +ATOM 1970 CB SER A 341 -55.387 -3.851 -45.503 1.00 40.38 C +ATOM 1971 OG SER A 341 -56.629 -3.227 -45.214 1.00 43.01 O +ATOM 1972 N ALA A 342 -56.307 -5.673 -42.690 1.00 38.00 N +ATOM 1973 CA ALA A 342 -57.097 -6.786 -42.183 1.00 38.00 C +ATOM 1974 C ALA A 342 -58.223 -7.120 -43.148 1.00 40.30 C +ATOM 1975 O ALA A 342 -58.839 -6.236 -43.748 1.00 42.53 O +ATOM 1976 CB ALA A 342 -57.671 -6.461 -40.806 1.00 38.00 C +ATOM 1977 N PHE A 343 -58.503 -8.407 -43.276 1.00 42.36 N +ATOM 1978 CA PHE A 343 -59.479 -8.881 -44.240 1.00 39.99 C +ATOM 1979 C PHE A 343 -60.894 -8.677 -43.728 1.00 38.84 C +ATOM 1980 O PHE A 343 -61.181 -8.888 -42.548 1.00 45.99 O +ATOM 1981 CB PHE A 343 -59.247 -10.359 -44.527 1.00 45.70 C +ATOM 1982 CG PHE A 343 -58.769 -10.631 -45.909 1.00 48.10 C +ATOM 1983 CD1 PHE A 343 -57.607 -10.048 -46.379 1.00 42.61 C +ATOM 1984 CD2 PHE A 343 -59.478 -11.480 -46.738 1.00 49.42 C +ATOM 1985 CE1 PHE A 343 -57.165 -10.302 -47.652 1.00 43.88 C +ATOM 1986 CE2 PHE A 343 -59.040 -11.739 -48.009 1.00 51.23 C +ATOM 1987 CZ PHE A 343 -57.884 -11.148 -48.470 1.00 49.25 C +ATOM 1988 N LEU A 344 -61.777 -8.255 -44.620 1.00 40.12 N +ATOM 1989 CA LEU A 344 -63.182 -8.200 -44.284 1.00 47.06 C +ATOM 1990 C LEU A 344 -63.740 -9.623 -44.203 1.00 50.77 C +ATOM 1991 O LEU A 344 -63.102 -10.575 -44.663 1.00 45.57 O +ATOM 1992 CB LEU A 344 -63.936 -7.372 -45.319 1.00 50.18 C +ATOM 1993 CG LEU A 344 -63.517 -5.904 -45.440 1.00 46.39 C +ATOM 1994 CD1 LEU A 344 -64.404 -5.185 -46.434 1.00 51.38 C +ATOM 1995 CD2 LEU A 344 -63.553 -5.207 -44.102 1.00 45.56 C +ATOM 1996 N PRO A 345 -64.915 -9.802 -43.592 1.00 52.05 N +ATOM 1997 CA PRO A 345 -65.511 -11.140 -43.531 1.00 51.96 C +ATOM 1998 C PRO A 345 -65.751 -11.711 -44.920 1.00 61.19 C +ATOM 1999 O PRO A 345 -65.874 -10.986 -45.911 1.00 58.41 O +ATOM 2000 CB PRO A 345 -66.835 -10.908 -42.795 1.00 48.42 C +ATOM 2001 CG PRO A 345 -66.608 -9.698 -41.991 1.00 46.68 C +ATOM 2002 CD PRO A 345 -65.705 -8.828 -42.818 1.00 49.20 C +ATOM 2003 N SER A 346 -65.816 -13.041 -44.975 1.00 71.07 N +ATOM 2004 CA SER A 346 -65.987 -13.743 -46.241 1.00 72.25 C +ATOM 2005 C SER A 346 -67.305 -13.364 -46.902 1.00 65.64 C +ATOM 2006 O SER A 346 -68.337 -13.224 -46.240 1.00 57.62 O +ATOM 2007 CB SER A 346 -65.936 -15.257 -46.022 1.00 75.40 C +ATOM 2008 OG SER A 346 -64.670 -15.664 -45.532 1.00 81.46 O +ATOM 2009 N LEU A 347 -67.268 -13.229 -48.230 1.00 67.63 N +ATOM 2010 CA LEU A 347 -68.457 -12.864 -48.989 1.00 65.32 C +ATOM 2011 C LEU A 347 -69.538 -13.927 -48.934 1.00 68.75 C +ATOM 2012 O LEU A 347 -70.677 -13.645 -49.321 1.00 62.31 O +ATOM 2013 CB LEU A 347 -68.083 -12.581 -50.442 1.00 55.95 C +ATOM 2014 CG LEU A 347 -67.279 -11.299 -50.635 1.00 55.81 C +ATOM 2015 CD1 LEU A 347 -65.895 -11.599 -51.194 1.00 54.10 C +ATOM 2016 CD2 LEU A 347 -68.056 -10.336 -51.529 1.00 48.39 C +ATOM 2017 N ASN A 348 -69.210 -15.131 -48.462 1.00 80.59 N +ATOM 2018 CA ASN A 348 -70.219 -16.148 -48.207 1.00 83.14 C +ATOM 2019 C ASN A 348 -70.992 -15.871 -46.926 1.00 83.03 C +ATOM 2020 O ASN A 348 -72.131 -16.334 -46.790 1.00 79.15 O +ATOM 2021 CB ASN A 348 -69.559 -17.529 -48.125 1.00 78.99 C +ATOM 2022 CG ASN A 348 -68.895 -17.943 -49.429 1.00 78.68 C +ATOM 2023 OD1 ASN A 348 -69.295 -17.513 -50.511 1.00 79.73 O +ATOM 2024 ND2 ASN A 348 -67.863 -18.774 -49.329 1.00 74.58 N +ATOM 2025 N LEU A 349 -70.418 -15.086 -46.013 1.00 76.17 N +ATOM 2026 CA LEU A 349 -71.072 -14.714 -44.764 1.00 69.42 C +ATOM 2027 C LEU A 349 -71.617 -13.293 -44.783 1.00 69.76 C +ATOM 2028 O LEU A 349 -72.663 -13.033 -44.178 1.00 66.25 O +ATOM 2029 CB LEU A 349 -70.092 -14.858 -43.591 1.00 66.70 C +ATOM 2030 CG LEU A 349 -69.497 -16.244 -43.326 1.00 61.75 C +ATOM 2031 CD1 LEU A 349 -68.517 -16.226 -42.156 1.00 52.72 C +ATOM 2032 CD2 LEU A 349 -70.608 -17.240 -43.069 1.00 67.66 C +ATOM 2033 N ALA A 350 -70.947 -12.380 -45.487 1.00 67.83 N +ATOM 2034 CA ALA A 350 -71.359 -10.979 -45.571 1.00 60.81 C +ATOM 2035 C ALA A 350 -71.134 -10.499 -46.994 1.00 59.81 C +ATOM 2036 O ALA A 350 -70.055 -9.989 -47.328 1.00 53.51 O +ATOM 2037 CB ALA A 350 -70.593 -10.108 -44.577 1.00 64.19 C +ATOM 2038 N PRO A 351 -72.119 -10.681 -47.876 1.00 62.53 N +ATOM 2039 CA PRO A 351 -71.944 -10.259 -49.271 1.00 63.16 C +ATOM 2040 C PRO A 351 -71.785 -8.750 -49.385 1.00 61.34 C +ATOM 2041 O PRO A 351 -72.397 -7.974 -48.647 1.00 56.45 O +ATOM 2042 CB PRO A 351 -73.230 -10.739 -49.955 1.00 58.00 C +ATOM 2043 CG PRO A 351 -73.808 -11.763 -49.030 1.00 54.75 C +ATOM 2044 CD PRO A 351 -73.421 -11.326 -47.653 1.00 54.77 C +ATOM 2045 N ARG A 352 -70.995 -8.338 -50.367 1.00 60.56 N +ATOM 2046 CA ARG A 352 -70.710 -6.934 -50.589 1.00 56.84 C +ATOM 2047 C ARG A 352 -71.121 -6.543 -51.998 1.00 58.71 C +ATOM 2048 O ARG A 352 -71.279 -7.388 -52.882 1.00 69.03 O +ATOM 2049 CB ARG A 352 -69.228 -6.626 -50.371 1.00 48.99 C +ATOM 2050 CG ARG A 352 -68.766 -6.932 -48.980 1.00 41.37 C +ATOM 2051 CD ARG A 352 -67.489 -6.208 -48.689 1.00 41.85 C +ATOM 2052 NE ARG A 352 -66.355 -6.776 -49.403 1.00 43.42 N +ATOM 2053 CZ ARG A 352 -65.674 -7.829 -48.972 1.00 50.20 C +ATOM 2054 NH1 ARG A 352 -66.032 -8.421 -47.840 1.00 49.38 N +ATOM 2055 NH2 ARG A 352 -64.643 -8.290 -49.669 1.00 52.18 N +ATOM 2056 N LEU A 353 -71.263 -5.239 -52.202 1.00 51.75 N +ATOM 2057 CA LEU A 353 -71.826 -4.693 -53.431 1.00 47.71 C +ATOM 2058 C LEU A 353 -70.943 -3.538 -53.881 1.00 50.99 C +ATOM 2059 O LEU A 353 -71.014 -2.445 -53.318 1.00 56.59 O +ATOM 2060 CB LEU A 353 -73.265 -4.248 -53.200 1.00 42.10 C +ATOM 2061 CG LEU A 353 -74.248 -4.426 -54.351 1.00 50.38 C +ATOM 2062 CD1 LEU A 353 -75.649 -4.070 -53.873 1.00 47.18 C +ATOM 2063 CD2 LEU A 353 -73.847 -3.587 -55.573 1.00 42.53 C +ATOM 2064 N SER A 354 -70.087 -3.786 -54.866 1.00 51.59 N +ATOM 2065 CA SER A 354 -69.281 -2.718 -55.446 1.00 54.33 C +ATOM 2066 C SER A 354 -70.191 -1.795 -56.248 1.00 56.22 C +ATOM 2067 O SER A 354 -70.775 -2.205 -57.256 1.00 56.14 O +ATOM 2068 CB SER A 354 -68.168 -3.286 -56.321 1.00 61.31 C +ATOM 2069 OG SER A 354 -67.151 -2.323 -56.540 1.00 54.81 O +ATOM 2070 N VAL A 355 -70.357 -0.571 -55.773 1.00 55.04 N +ATOM 2071 CA VAL A 355 -71.203 0.431 -56.414 1.00 54.33 C +ATOM 2072 C VAL A 355 -70.296 1.452 -57.088 1.00 54.97 C +ATOM 2073 O VAL A 355 -69.316 1.892 -56.475 1.00 48.27 O +ATOM 2074 CB VAL A 355 -72.150 1.116 -55.408 1.00 52.53 C +ATOM 2075 CG1 VAL A 355 -72.862 2.287 -56.058 1.00 58.44 C +ATOM 2076 CG2 VAL A 355 -73.170 0.117 -54.891 1.00 48.17 C +ATOM 2077 N PRO A 356 -70.545 1.806 -58.348 1.00 60.57 N +ATOM 2078 CA PRO A 356 -69.748 2.857 -58.986 1.00 59.55 C +ATOM 2079 C PRO A 356 -70.061 4.225 -58.403 1.00 61.41 C +ATOM 2080 O PRO A 356 -71.222 4.577 -58.171 1.00 58.77 O +ATOM 2081 CB PRO A 356 -70.160 2.771 -60.460 1.00 62.65 C +ATOM 2082 CG PRO A 356 -71.523 2.167 -60.430 1.00 66.07 C +ATOM 2083 CD PRO A 356 -71.523 1.211 -59.275 1.00 62.05 C +ATOM 2084 N ASN A 357 -69.004 4.994 -58.166 1.00 58.05 N +ATOM 2085 CA ASN A 357 -69.157 6.353 -57.684 1.00 55.25 C +ATOM 2086 C ASN A 357 -69.908 7.200 -58.712 1.00 58.68 C +ATOM 2087 O ASN A 357 -69.800 6.965 -59.916 1.00 65.79 O +ATOM 2088 CB ASN A 357 -67.789 6.967 -57.405 1.00 49.74 C +ATOM 2089 CG ASN A 357 -67.878 8.230 -56.592 1.00 55.13 C +ATOM 2090 OD1 ASN A 357 -68.319 9.265 -57.083 1.00 54.69 O +ATOM 2091 ND2 ASN A 357 -67.461 8.154 -55.336 1.00 63.48 N +ATOM 2092 N PRO A 358 -70.698 8.180 -58.267 1.00 54.36 N +ATOM 2093 CA PRO A 358 -71.240 9.166 -59.213 1.00 54.87 C +ATOM 2094 C PRO A 358 -70.214 10.179 -59.694 1.00 53.64 C +ATOM 2095 O PRO A 358 -70.463 10.857 -60.699 1.00 58.17 O +ATOM 2096 CB PRO A 358 -72.358 9.848 -58.408 1.00 54.54 C +ATOM 2097 CG PRO A 358 -72.681 8.894 -57.308 1.00 56.17 C +ATOM 2098 CD PRO A 358 -71.390 8.221 -56.970 1.00 57.65 C +ATOM 2099 N TRP A 359 -69.062 10.281 -59.034 1.00 48.09 N +ATOM 2100 CA TRP A 359 -68.026 11.223 -59.436 1.00 50.01 C +ATOM 2101 C TRP A 359 -66.797 10.473 -59.928 1.00 50.15 C +ATOM 2102 O TRP A 359 -65.676 10.737 -59.477 1.00 45.87 O +ATOM 2103 CB TRP A 359 -67.646 12.160 -58.278 1.00 51.30 C +ATOM 2104 CG TRP A 359 -68.627 13.277 -58.032 1.00 50.46 C +ATOM 2105 CD1 TRP A 359 -68.541 14.553 -58.504 1.00 48.72 C +ATOM 2106 CD2 TRP A 359 -69.833 13.219 -57.253 1.00 50.74 C +ATOM 2107 NE1 TRP A 359 -69.619 15.290 -58.077 1.00 52.49 N +ATOM 2108 CE2 TRP A 359 -70.426 14.494 -57.308 1.00 49.47 C +ATOM 2109 CE3 TRP A 359 -70.468 12.214 -56.519 1.00 53.18 C +ATOM 2110 CZ2 TRP A 359 -71.623 14.789 -56.657 1.00 48.52 C +ATOM 2111 CZ3 TRP A 359 -71.659 12.513 -55.874 1.00 49.45 C +ATOM 2112 CH2 TRP A 359 -72.220 13.787 -55.948 1.00 43.05 C +ATOM 2113 N ILE A 360 -66.996 9.515 -60.836 1.00 56.10 N +ATOM 2114 CA ILE A 360 -65.849 8.825 -61.411 1.00 61.12 C +ATOM 2115 C ILE A 360 -65.048 9.792 -62.274 1.00 57.97 C +ATOM 2116 O ILE A 360 -65.537 10.836 -62.721 1.00 58.92 O +ATOM 2117 CB ILE A 360 -66.254 7.585 -62.225 1.00 57.91 C +ATOM 2118 CG1 ILE A 360 -67.699 7.174 -61.944 1.00 53.22 C +ATOM 2119 CG2 ILE A 360 -65.292 6.438 -61.936 1.00 48.91 C +ATOM 2120 CD1 ILE A 360 -68.738 7.813 -62.864 1.00 51.63 C +ATOM 2121 N ARG A 361 -63.797 9.431 -62.512 1.00 59.71 N +ATOM 2122 CA ARG A 361 -62.981 10.135 -63.481 1.00 65.25 C +ATOM 2123 C ARG A 361 -63.116 9.481 -64.856 1.00 68.41 C +ATOM 2124 O ARG A 361 -63.667 8.388 -65.007 1.00 69.82 O +ATOM 2125 CB ARG A 361 -61.525 10.157 -63.035 1.00 60.37 C +ATOM 2126 CG ARG A 361 -61.046 11.514 -62.597 1.00 58.71 C +ATOM 2127 CD ARG A 361 -61.020 11.637 -61.094 1.00 59.50 C +ATOM 2128 NE ARG A 361 -60.335 12.863 -60.699 1.00 68.58 N +ATOM 2129 CZ ARG A 361 -60.199 13.281 -59.446 1.00 62.38 C +ATOM 2130 NH1 ARG A 361 -60.705 12.569 -58.446 1.00 63.32 N +ATOM 2131 NH2 ARG A 361 -59.552 14.413 -59.195 1.00 49.50 N +ATOM 2132 N SER A 362 -62.630 10.188 -65.879 1.00 61.88 N +ATOM 2133 CA SER A 362 -62.667 9.641 -67.231 1.00 65.25 C +ATOM 2134 C SER A 362 -61.738 8.438 -67.380 1.00 65.61 C +ATOM 2135 O SER A 362 -62.006 7.549 -68.197 1.00 57.24 O +ATOM 2136 CB SER A 362 -62.315 10.731 -68.244 1.00 70.20 C +ATOM 2137 OG SER A 362 -61.022 11.265 -68.013 1.00 62.86 O +ATOM 2138 N TYR A 363 -60.642 8.405 -66.615 1.00 66.15 N +ATOM 2139 CA TYR A 363 -59.606 7.371 -66.719 1.00 59.16 C +ATOM 2140 C TYR A 363 -59.099 7.261 -68.152 1.00 57.36 C +ATOM 2141 O TYR A 363 -58.946 6.173 -68.708 1.00 57.39 O +ATOM 2142 CB TYR A 363 -60.098 6.022 -66.194 1.00 54.68 C +ATOM 2143 CG TYR A 363 -60.241 6.009 -64.691 1.00 61.81 C +ATOM 2144 CD1 TYR A 363 -59.139 5.803 -63.867 1.00 60.57 C +ATOM 2145 CD2 TYR A 363 -61.478 6.209 -64.093 1.00 63.82 C +ATOM 2146 CE1 TYR A 363 -59.269 5.803 -62.486 1.00 58.80 C +ATOM 2147 CE2 TYR A 363 -61.619 6.205 -62.721 1.00 62.75 C +ATOM 2148 CZ TYR A 363 -60.515 6.004 -61.922 1.00 63.28 C +ATOM 2149 OH TYR A 363 -60.664 6.003 -60.554 1.00 62.83 O +ATOM 2150 N THR A 364 -58.828 8.422 -68.740 1.00 57.77 N +ATOM 2151 CA THR A 364 -58.294 8.534 -70.084 1.00 54.98 C +ATOM 2152 C THR A 364 -57.261 9.647 -70.092 1.00 61.51 C +ATOM 2153 O THR A 364 -57.183 10.454 -69.161 1.00 64.16 O +ATOM 2154 CB THR A 364 -59.387 8.843 -71.113 1.00 49.50 C +ATOM 2155 OG1 THR A 364 -60.664 8.483 -70.575 1.00 39.33 O +ATOM 2156 CG2 THR A 364 -59.133 8.078 -72.412 1.00 49.80 C +ATOM 2157 N LEU A 365 -56.454 9.675 -71.153 1.00 60.73 N +ATOM 2158 CA LEU A 365 -55.480 10.750 -71.309 1.00 67.49 C +ATOM 2159 C LEU A 365 -56.131 12.108 -71.576 1.00 66.15 C +ATOM 2160 O LEU A 365 -55.455 13.137 -71.460 1.00 61.17 O +ATOM 2161 CB LEU A 365 -54.493 10.396 -72.423 1.00 65.22 C +ATOM 2162 CG LEU A 365 -53.627 9.162 -72.148 1.00 56.73 C +ATOM 2163 CD1 LEU A 365 -52.689 8.868 -73.310 1.00 60.66 C +ATOM 2164 CD2 LEU A 365 -52.842 9.348 -70.867 1.00 52.66 C +ATOM 2165 N ALA A 366 -57.419 12.137 -71.908 1.00 58.56 N +ATOM 2166 CA ALA A 366 -58.156 13.374 -72.106 1.00 49.78 C +ATOM 2167 C ALA A 366 -59.619 13.100 -71.782 1.00 55.00 C +ATOM 2168 O ALA A 366 -59.989 11.995 -71.374 1.00 54.45 O +ATOM 2169 CB ALA A 366 -57.968 13.910 -73.528 1.00 52.99 C +ATOM 2170 N GLY A 367 -60.453 14.121 -71.939 1.00 54.40 N +ATOM 2171 CA GLY A 367 -61.864 13.941 -71.671 1.00 54.56 C +ATOM 2172 C GLY A 367 -62.206 14.096 -70.205 1.00 61.85 C +ATOM 2173 O GLY A 367 -61.495 13.596 -69.328 1.00 58.38 O +ATOM 2174 N LYS A 368 -63.288 14.817 -69.934 1.00 68.80 N +ATOM 2175 CA LYS A 368 -63.766 15.054 -68.583 1.00 64.51 C +ATOM 2176 C LYS A 368 -65.171 14.490 -68.431 1.00 63.30 C +ATOM 2177 O LYS A 368 -65.921 14.375 -69.406 1.00 57.78 O +ATOM 2178 CB LYS A 368 -63.775 16.554 -68.227 1.00 70.42 C +ATOM 2179 CG LYS A 368 -63.390 17.506 -69.358 1.00 75.54 C +ATOM 2180 CD LYS A 368 -61.872 17.686 -69.470 1.00 70.04 C +ATOM 2181 CE LYS A 368 -61.270 18.241 -68.183 1.00 68.05 C +ATOM 2182 NZ LYS A 368 -59.792 18.426 -68.285 1.00 69.17 N +ATOM 2183 N GLU A 369 -65.517 14.138 -67.197 1.00 63.98 N +ATOM 2184 CA GLU A 369 -66.851 13.648 -66.901 1.00 62.46 C +ATOM 2185 C GLU A 369 -67.824 14.821 -66.764 1.00 61.24 C +ATOM 2186 O GLU A 369 -67.443 15.995 -66.819 1.00 57.92 O +ATOM 2187 CB GLU A 369 -66.826 12.782 -65.644 1.00 60.21 C +ATOM 2188 CG GLU A 369 -66.152 11.433 -65.840 1.00 66.81 C +ATOM 2189 CD GLU A 369 -66.950 10.501 -66.740 1.00 77.74 C +ATOM 2190 OE1 GLU A 369 -68.185 10.681 -66.841 1.00 77.03 O +ATOM 2191 OE2 GLU A 369 -66.341 9.589 -67.345 1.00 72.44 O +ATOM 2192 N GLU A 370 -69.106 14.489 -66.577 1.00 60.62 N +ATOM 2193 CA GLU A 370 -70.147 15.513 -66.526 1.00 60.91 C +ATOM 2194 C GLU A 370 -69.963 16.435 -65.326 1.00 56.61 C +ATOM 2195 O GLU A 370 -70.116 17.657 -65.444 1.00 50.59 O +ATOM 2196 CB GLU A 370 -71.525 14.848 -66.491 1.00 67.91 C +ATOM 2197 CG GLU A 370 -72.563 15.497 -67.403 1.00 76.98 C +ATOM 2198 CD GLU A 370 -73.593 16.331 -66.651 1.00 80.16 C +ATOM 2199 OE1 GLU A 370 -74.244 15.795 -65.724 1.00 79.32 O +ATOM 2200 OE2 GLU A 370 -73.754 17.523 -66.991 1.00 76.05 O +ATOM 2201 N TRP A 371 -69.644 15.863 -64.158 1.00 62.61 N +ATOM 2202 CA TRP A 371 -69.429 16.659 -62.952 1.00 57.90 C +ATOM 2203 C TRP A 371 -68.219 17.575 -63.082 1.00 59.56 C +ATOM 2204 O TRP A 371 -68.145 18.604 -62.400 1.00 59.79 O +ATOM 2205 CB TRP A 371 -69.246 15.748 -61.738 1.00 51.77 C +ATOM 2206 CG TRP A 371 -68.019 14.888 -61.814 1.00 52.35 C +ATOM 2207 CD1 TRP A 371 -67.941 13.621 -62.309 1.00 52.90 C +ATOM 2208 CD2 TRP A 371 -66.691 15.238 -61.393 1.00 50.04 C +ATOM 2209 NE1 TRP A 371 -66.649 13.158 -62.219 1.00 57.25 N +ATOM 2210 CE2 TRP A 371 -65.863 14.132 -61.660 1.00 53.93 C +ATOM 2211 CE3 TRP A 371 -66.124 16.377 -60.813 1.00 51.84 C +ATOM 2212 CZ2 TRP A 371 -64.497 14.129 -61.366 1.00 54.46 C +ATOM 2213 CZ3 TRP A 371 -64.768 16.372 -60.523 1.00 52.99 C +ATOM 2214 CH2 TRP A 371 -63.971 15.255 -60.799 1.00 48.17 C +ATOM 2215 N GLU A 372 -67.245 17.204 -63.916 1.00 52.90 N +ATOM 2216 CA GLU A 372 -66.067 18.042 -64.084 1.00 48.77 C +ATOM 2217 C GLU A 372 -66.366 19.346 -64.808 1.00 58.41 C +ATOM 2218 O GLU A 372 -65.550 20.270 -64.733 1.00 58.55 O +ATOM 2219 CB GLU A 372 -64.973 17.283 -64.835 1.00 52.47 C +ATOM 2220 CG GLU A 372 -63.862 16.768 -63.936 1.00 59.38 C +ATOM 2221 CD GLU A 372 -62.906 15.820 -64.637 1.00 55.46 C +ATOM 2222 OE1 GLU A 372 -63.383 14.890 -65.325 1.00 55.75 O +ATOM 2223 OE2 GLU A 372 -61.677 16.008 -64.490 1.00 38.00 O +ATOM 2224 N VAL A 373 -67.518 19.460 -65.472 1.00 63.38 N +ATOM 2225 CA VAL A 373 -67.805 20.622 -66.308 1.00 58.59 C +ATOM 2226 C VAL A 373 -69.069 21.339 -65.843 1.00 53.91 C +ATOM 2227 O VAL A 373 -69.175 22.564 -65.962 1.00 53.97 O +ATOM 2228 CB VAL A 373 -67.923 20.211 -67.788 1.00 58.81 C +ATOM 2229 CG1 VAL A 373 -68.065 21.443 -68.676 1.00 63.42 C +ATOM 2230 CG2 VAL A 373 -66.721 19.360 -68.214 1.00 50.94 C +ATOM 2231 N ASN A 374 -70.033 20.591 -65.300 1.00 52.02 N +ATOM 2232 CA ASN A 374 -71.311 21.163 -64.899 1.00 53.76 C +ATOM 2233 C ASN A 374 -71.328 21.384 -63.393 1.00 66.58 C +ATOM 2234 O ASN A 374 -71.386 20.402 -62.637 1.00 69.38 O +ATOM 2235 CB ASN A 374 -72.468 20.253 -65.315 1.00 53.15 C +ATOM 2236 CG ASN A 374 -73.820 20.743 -64.804 1.00 57.99 C +ATOM 2237 OD1 ASN A 374 -73.985 21.912 -64.453 1.00 59.19 O +ATOM 2238 ND2 ASN A 374 -74.797 19.841 -64.765 1.00 54.81 N +ATOM 2239 N PRO A 375 -71.278 22.630 -62.907 1.00 67.73 N +ATOM 2240 CA PRO A 375 -71.384 22.858 -61.457 1.00 61.97 C +ATOM 2241 C PRO A 375 -72.730 22.467 -60.874 1.00 57.29 C +ATOM 2242 O PRO A 375 -72.840 22.354 -59.647 1.00 59.44 O +ATOM 2243 CB PRO A 375 -71.141 24.368 -61.316 1.00 64.03 C +ATOM 2244 CG PRO A 375 -70.493 24.791 -62.592 1.00 61.48 C +ATOM 2245 CD PRO A 375 -71.030 23.879 -63.646 1.00 65.13 C +ATOM 2246 N LEU A 376 -73.750 22.243 -61.703 1.00 52.50 N +ATOM 2247 CA LEU A 376 -75.060 21.806 -61.237 1.00 62.76 C +ATOM 2248 C LEU A 376 -75.219 20.294 -61.314 1.00 70.06 C +ATOM 2249 O LEU A 376 -76.342 19.792 -61.443 1.00 72.12 O +ATOM 2250 CB LEU A 376 -76.165 22.488 -62.040 1.00 63.30 C +ATOM 2251 CG LEU A 376 -76.246 24.009 -61.952 1.00 72.98 C +ATOM 2252 CD1 LEU A 376 -77.189 24.537 -63.017 1.00 75.82 C +ATOM 2253 CD2 LEU A 376 -76.704 24.437 -60.566 1.00 69.59 C +ATOM 2254 N TYR A 377 -74.108 19.559 -61.223 1.00 70.17 N +ATOM 2255 CA TYR A 377 -74.155 18.108 -61.381 1.00 69.92 C +ATOM 2256 C TYR A 377 -74.984 17.452 -60.284 1.00 70.17 C +ATOM 2257 O TYR A 377 -75.751 16.519 -60.553 1.00 64.53 O +ATOM 2258 CB TYR A 377 -72.733 17.542 -61.392 1.00 64.64 C +ATOM 2259 CG TYR A 377 -72.657 16.044 -61.599 1.00 66.51 C +ATOM 2260 CD1 TYR A 377 -72.889 15.486 -62.849 1.00 68.83 C +ATOM 2261 CD2 TYR A 377 -72.343 15.189 -60.550 1.00 64.43 C +ATOM 2262 CE1 TYR A 377 -72.818 14.120 -63.048 1.00 70.18 C +ATOM 2263 CE2 TYR A 377 -72.263 13.822 -60.740 1.00 61.56 C +ATOM 2264 CZ TYR A 377 -72.505 13.292 -61.990 1.00 67.17 C +ATOM 2265 OH TYR A 377 -72.433 11.930 -62.183 1.00 76.94 O +ATOM 2266 N CYS A 378 -74.858 17.937 -59.045 1.00 70.46 N +ATOM 2267 CA CYS A 378 -75.555 17.308 -57.927 1.00 75.86 C +ATOM 2268 C CYS A 378 -77.058 17.550 -57.959 1.00 74.00 C +ATOM 2269 O CYS A 378 -77.806 16.790 -57.335 1.00 71.57 O +ATOM 2270 CB CYS A 378 -74.977 17.791 -56.593 1.00 72.18 C +ATOM 2271 SG CYS A 378 -75.561 16.839 -55.146 1.00 74.61 S +ATOM 2272 N ASP A 379 -77.520 18.586 -58.659 1.00 75.00 N +ATOM 2273 CA ASP A 379 -78.959 18.759 -58.819 1.00 76.19 C +ATOM 2274 C ASP A 379 -79.578 17.579 -59.555 1.00 77.49 C +ATOM 2275 O ASP A 379 -80.732 17.218 -59.294 1.00 73.86 O +ATOM 2276 CB ASP A 379 -79.242 20.070 -59.547 1.00 78.52 C +ATOM 2277 CG ASP A 379 -79.029 21.276 -58.659 1.00 78.99 C +ATOM 2278 OD1 ASP A 379 -79.196 21.141 -57.428 1.00 69.52 O +ATOM 2279 OD2 ASP A 379 -78.676 22.350 -59.187 1.00 83.08 O +ATOM 2280 N THR A 380 -78.816 16.949 -60.451 1.00 73.87 N +ATOM 2281 CA THR A 380 -79.282 15.727 -61.093 1.00 72.51 C +ATOM 2282 C THR A 380 -79.131 14.533 -60.161 1.00 71.17 C +ATOM 2283 O THR A 380 -80.037 13.698 -60.065 1.00 68.70 O +ATOM 2284 CB THR A 380 -78.506 15.484 -62.389 1.00 74.98 C +ATOM 2285 OG1 THR A 380 -78.554 16.659 -63.204 1.00 94.26 O +ATOM 2286 CG2 THR A 380 -79.112 14.321 -63.163 1.00 71.76 C +ATOM 2287 N VAL A 381 -78.009 14.468 -59.435 1.00 67.85 N +ATOM 2288 CA VAL A 381 -77.724 13.311 -58.588 1.00 62.06 C +ATOM 2289 C VAL A 381 -78.779 13.176 -57.502 1.00 63.35 C +ATOM 2290 O VAL A 381 -79.198 12.064 -57.157 1.00 64.36 O +ATOM 2291 CB VAL A 381 -76.310 13.423 -57.983 1.00 56.30 C +ATOM 2292 CG1 VAL A 381 -75.968 12.169 -57.193 1.00 52.82 C +ATOM 2293 CG2 VAL A 381 -75.277 13.685 -59.060 1.00 59.41 C +ATOM 2294 N LYS A 382 -79.226 14.304 -56.946 1.00 67.33 N +ATOM 2295 CA LYS A 382 -80.210 14.290 -55.871 1.00 65.12 C +ATOM 2296 C LYS A 382 -81.552 13.710 -56.299 1.00 70.73 C +ATOM 2297 O LYS A 382 -82.392 13.440 -55.434 1.00 74.83 O +ATOM 2298 CB LYS A 382 -80.412 15.705 -55.321 1.00 62.74 C +ATOM 2299 CG LYS A 382 -79.195 16.271 -54.601 1.00 62.42 C +ATOM 2300 CD LYS A 382 -79.472 17.650 -54.018 1.00 56.91 C +ATOM 2301 CE LYS A 382 -78.242 18.205 -53.315 1.00 55.13 C +ATOM 2302 NZ LYS A 382 -78.492 19.540 -52.710 1.00 53.97 N +ATOM 2303 N GLN A 383 -81.782 13.518 -57.598 1.00 66.65 N +ATOM 2304 CA GLN A 383 -83.054 13.011 -58.094 1.00 69.54 C +ATOM 2305 C GLN A 383 -82.940 11.609 -58.688 1.00 72.41 C +ATOM 2306 O GLN A 383 -83.856 11.157 -59.384 1.00 70.21 O +ATOM 2307 CB GLN A 383 -83.623 13.988 -59.122 1.00 81.54 C +ATOM 2308 CG GLN A 383 -83.791 15.403 -58.581 1.00 81.75 C +ATOM 2309 CD GLN A 383 -84.234 16.392 -59.642 1.00 90.56 C +ATOM 2310 OE1 GLN A 383 -83.944 16.225 -60.831 1.00 87.17 O +ATOM 2311 NE2 GLN A 383 -84.956 17.425 -59.217 1.00 85.15 N +ATOM 2312 N ILE A 384 -81.849 10.900 -58.403 1.00 78.72 N +ATOM 2313 CA ILE A 384 -81.608 9.554 -58.914 1.00 75.81 C +ATOM 2314 C ILE A 384 -81.529 8.598 -57.729 1.00 80.41 C +ATOM 2315 O ILE A 384 -80.788 8.846 -56.770 1.00 84.06 O +ATOM 2316 CB ILE A 384 -80.324 9.497 -59.770 1.00 61.38 C +ATOM 2317 CG1 ILE A 384 -80.636 9.716 -61.255 1.00 63.14 C +ATOM 2318 CG2 ILE A 384 -79.596 8.170 -59.601 1.00 56.60 C +ATOM 2319 CD1 ILE A 384 -81.138 11.101 -61.614 1.00 60.55 C +ATOM 2320 N TYR A 385 -82.300 7.519 -57.791 1.00 75.65 N +ATOM 2321 CA TYR A 385 -82.243 6.493 -56.760 1.00 78.38 C +ATOM 2322 C TYR A 385 -80.889 5.783 -56.817 1.00 79.80 C +ATOM 2323 O TYR A 385 -80.330 5.599 -57.903 1.00 78.17 O +ATOM 2324 CB TYR A 385 -83.395 5.504 -56.959 1.00 77.78 C +ATOM 2325 CG TYR A 385 -83.398 4.302 -56.045 1.00 84.35 C +ATOM 2326 CD1 TYR A 385 -84.053 4.331 -54.820 1.00 82.63 C +ATOM 2327 CD2 TYR A 385 -82.749 3.130 -56.415 1.00 92.17 C +ATOM 2328 CE1 TYR A 385 -84.056 3.222 -53.986 1.00 90.13 C +ATOM 2329 CE2 TYR A 385 -82.745 2.023 -55.592 1.00 94.55 C +ATOM 2330 CZ TYR A 385 -83.400 2.072 -54.381 1.00 96.62 C +ATOM 2331 OH TYR A 385 -83.393 0.963 -53.566 1.00102.02 O +ATOM 2332 N PRO A 386 -80.314 5.393 -55.664 1.00 81.74 N +ATOM 2333 CA PRO A 386 -80.849 5.546 -54.310 1.00 87.60 C +ATOM 2334 C PRO A 386 -80.349 6.795 -53.586 1.00 87.11 C +ATOM 2335 O PRO A 386 -80.301 6.805 -52.355 1.00 89.55 O +ATOM 2336 CB PRO A 386 -80.345 4.283 -53.612 1.00 89.56 C +ATOM 2337 CG PRO A 386 -78.998 4.067 -54.230 1.00 82.79 C +ATOM 2338 CD PRO A 386 -79.093 4.565 -55.664 1.00 78.68 C +ATOM 2339 N TYR A 387 -79.977 7.827 -54.340 1.00 80.45 N +ATOM 2340 CA TYR A 387 -79.545 9.090 -53.759 1.00 73.19 C +ATOM 2341 C TYR A 387 -80.708 10.036 -53.494 1.00 75.82 C +ATOM 2342 O TYR A 387 -80.486 11.160 -53.031 1.00 69.06 O +ATOM 2343 CB TYR A 387 -78.511 9.754 -54.671 1.00 58.95 C +ATOM 2344 CG TYR A 387 -77.358 8.838 -55.015 1.00 63.53 C +ATOM 2345 CD1 TYR A 387 -77.436 7.968 -56.093 1.00 72.72 C +ATOM 2346 CD2 TYR A 387 -76.192 8.839 -54.260 1.00 69.10 C +ATOM 2347 CE1 TYR A 387 -76.385 7.123 -56.411 1.00 77.77 C +ATOM 2348 CE2 TYR A 387 -75.132 7.997 -54.571 1.00 72.53 C +ATOM 2349 CZ TYR A 387 -75.235 7.141 -55.651 1.00 75.09 C +ATOM 2350 OH TYR A 387 -74.193 6.297 -55.980 1.00 65.98 O +ATOM 2351 N ASN A 388 -81.942 9.592 -53.759 1.00 80.20 N +ATOM 2352 CA ASN A 388 -83.133 10.384 -53.482 1.00 79.73 C +ATOM 2353 C ASN A 388 -83.488 10.407 -52.002 1.00 82.97 C +ATOM 2354 O ASN A 388 -84.154 11.348 -51.556 1.00 77.36 O +ATOM 2355 CB ASN A 388 -84.324 9.859 -54.299 1.00 78.66 C +ATOM 2356 CG ASN A 388 -84.620 8.377 -54.049 1.00 77.97 C +ATOM 2357 OD1 ASN A 388 -83.730 7.596 -53.711 1.00 74.54 O +ATOM 2358 ND2 ASN A 388 -85.883 7.994 -54.202 1.00 81.28 N +ATOM 2359 N ASN A 389 -83.061 9.396 -51.237 1.00 92.97 N +ATOM 2360 CA ASN A 389 -83.334 9.340 -49.804 1.00 98.22 C +ATOM 2361 C ASN A 389 -82.507 10.337 -48.999 1.00 95.95 C +ATOM 2362 O ASN A 389 -82.755 10.486 -47.795 1.00 89.69 O +ATOM 2363 CB ASN A 389 -83.110 7.916 -49.266 1.00 93.38 C +ATOM 2364 CG ASN A 389 -81.702 7.394 -49.523 1.00 84.88 C +ATOM 2365 OD1 ASN A 389 -80.739 7.834 -48.898 1.00 88.16 O +ATOM 2366 ND2 ASN A 389 -81.585 6.428 -50.423 1.00 82.00 N +ATOM 2367 N SER A 390 -81.540 11.012 -49.626 1.00 92.20 N +ATOM 2368 CA SER A 390 -80.709 12.042 -48.998 1.00 98.57 C +ATOM 2369 C SER A 390 -79.921 11.523 -47.794 1.00 86.62 C +ATOM 2370 O SER A 390 -79.471 12.311 -46.957 1.00 77.45 O +ATOM 2371 CB SER A 390 -81.552 13.258 -48.590 1.00100.52 C +ATOM 2372 OG SER A 390 -82.152 13.882 -49.714 1.00 87.86 O +ATOM 2373 N GLN A 391 -79.746 10.208 -47.688 1.00 88.28 N +ATOM 2374 CA GLN A 391 -78.919 9.589 -46.660 1.00 79.34 C +ATOM 2375 C GLN A 391 -77.708 8.865 -47.230 1.00 69.24 C +ATOM 2376 O GLN A 391 -76.652 8.846 -46.591 1.00 56.92 O +ATOM 2377 CB GLN A 391 -79.759 8.598 -45.829 1.00 74.49 C +ATOM 2378 CG GLN A 391 -79.065 8.032 -44.598 1.00 69.32 C +ATOM 2379 CD GLN A 391 -78.801 9.080 -43.537 1.00 69.02 C +ATOM 2380 OE1 GLN A 391 -79.591 10.009 -43.351 1.00 71.68 O +ATOM 2381 NE2 GLN A 391 -77.678 8.940 -42.837 1.00 57.50 N +ATOM 2382 N ARG A 392 -77.839 8.273 -48.419 1.00 75.45 N +ATOM 2383 CA ARG A 392 -76.688 7.700 -49.106 1.00 75.05 C +ATOM 2384 C ARG A 392 -75.753 8.795 -49.597 1.00 69.44 C +ATOM 2385 O ARG A 392 -74.525 8.646 -49.547 1.00 61.31 O +ATOM 2386 CB ARG A 392 -77.163 6.832 -50.275 1.00 82.89 C +ATOM 2387 CG ARG A 392 -76.086 6.448 -51.298 1.00 79.02 C +ATOM 2388 CD ARG A 392 -75.307 5.217 -50.857 1.00 72.56 C +ATOM 2389 NE ARG A 392 -76.109 4.003 -50.975 1.00 70.71 N +ATOM 2390 CZ ARG A 392 -76.257 3.316 -52.101 1.00 70.73 C +ATOM 2391 NH1 ARG A 392 -75.654 3.728 -53.206 1.00 69.20 N +ATOM 2392 NH2 ARG A 392 -77.006 2.221 -52.120 1.00 75.34 N +ATOM 2393 N LEU A 393 -76.320 9.910 -50.064 1.00 69.65 N +ATOM 2394 CA LEU A 393 -75.490 11.006 -50.552 1.00 71.32 C +ATOM 2395 C LEU A 393 -74.600 11.560 -49.451 1.00 63.39 C +ATOM 2396 O LEU A 393 -73.439 11.903 -49.704 1.00 54.72 O +ATOM 2397 CB LEU A 393 -76.370 12.115 -51.138 1.00 71.42 C +ATOM 2398 CG LEU A 393 -75.655 13.293 -51.809 1.00 58.07 C +ATOM 2399 CD1 LEU A 393 -74.701 12.812 -52.892 1.00 59.68 C +ATOM 2400 CD2 LEU A 393 -76.670 14.261 -52.386 1.00 51.49 C +ATOM 2401 N LEU A 394 -75.102 11.604 -48.217 1.00 65.23 N +ATOM 2402 CA LEU A 394 -74.291 12.121 -47.125 1.00 57.31 C +ATOM 2403 C LEU A 394 -73.083 11.238 -46.885 1.00 56.10 C +ATOM 2404 O LEU A 394 -71.980 11.740 -46.645 1.00 57.94 O +ATOM 2405 CB LEU A 394 -75.125 12.230 -45.854 1.00 59.61 C +ATOM 2406 CG LEU A 394 -76.293 13.199 -45.945 1.00 65.12 C +ATOM 2407 CD1 LEU A 394 -77.136 13.144 -44.683 1.00 66.76 C +ATOM 2408 CD2 LEU A 394 -75.743 14.594 -46.170 1.00 62.09 C +ATOM 2409 N ASN A 395 -73.262 9.921 -46.982 1.00 56.13 N +ATOM 2410 CA ASN A 395 -72.127 9.023 -46.814 1.00 60.41 C +ATOM 2411 C ASN A 395 -71.093 9.215 -47.915 1.00 58.06 C +ATOM 2412 O ASN A 395 -69.891 9.055 -47.670 1.00 55.45 O +ATOM 2413 CB ASN A 395 -72.607 7.575 -46.766 1.00 62.09 C +ATOM 2414 CG ASN A 395 -73.398 7.273 -45.518 1.00 64.65 C +ATOM 2415 OD1 ASN A 395 -72.841 6.830 -44.509 1.00 62.51 O +ATOM 2416 ND2 ASN A 395 -74.707 7.518 -45.572 1.00 62.04 N +ATOM 2417 N VAL A 396 -71.531 9.578 -49.122 1.00 55.36 N +ATOM 2418 CA VAL A 396 -70.569 9.845 -50.185 1.00 54.50 C +ATOM 2419 C VAL A 396 -69.811 11.130 -49.898 1.00 51.01 C +ATOM 2420 O VAL A 396 -68.640 11.269 -50.275 1.00 43.11 O +ATOM 2421 CB VAL A 396 -71.276 9.905 -51.547 1.00 55.76 C +ATOM 2422 CG1 VAL A 396 -70.251 10.006 -52.666 1.00 47.34 C +ATOM 2423 CG2 VAL A 396 -72.181 8.698 -51.726 1.00 62.18 C +ATOM 2424 N ILE A 397 -70.464 12.090 -49.242 1.00 55.88 N +ATOM 2425 CA ILE A 397 -69.796 13.335 -48.874 1.00 51.14 C +ATOM 2426 C ILE A 397 -68.655 13.059 -47.905 1.00 48.70 C +ATOM 2427 O ILE A 397 -67.556 13.611 -48.040 1.00 49.94 O +ATOM 2428 CB ILE A 397 -70.806 14.325 -48.272 1.00 50.00 C +ATOM 2429 CG1 ILE A 397 -71.972 14.562 -49.239 1.00 47.59 C +ATOM 2430 CG2 ILE A 397 -70.100 15.617 -47.900 1.00 47.93 C +ATOM 2431 CD1 ILE A 397 -71.609 15.340 -50.473 1.00 50.46 C +ATOM 2432 N ASP A 398 -68.911 12.225 -46.893 1.00 48.42 N +ATOM 2433 CA ASP A 398 -67.850 11.855 -45.962 1.00 45.15 C +ATOM 2434 C ASP A 398 -66.694 11.194 -46.694 1.00 46.30 C +ATOM 2435 O ASP A 398 -65.527 11.532 -46.461 1.00 40.11 O +ATOM 2436 CB ASP A 398 -68.392 10.920 -44.883 1.00 50.60 C +ATOM 2437 CG ASP A 398 -69.348 11.611 -43.932 1.00 53.32 C +ATOM 2438 OD1 ASP A 398 -69.933 12.650 -44.306 1.00 49.09 O +ATOM 2439 OD2 ASP A 398 -69.519 11.106 -42.804 1.00 61.25 O +ATOM 2440 N MET A 399 -67.003 10.262 -47.601 1.00 50.61 N +ATOM 2441 CA MET A 399 -65.955 9.608 -48.378 1.00 58.09 C +ATOM 2442 C MET A 399 -65.169 10.627 -49.192 1.00 48.64 C +ATOM 2443 O MET A 399 -63.943 10.522 -49.317 1.00 50.60 O +ATOM 2444 CB MET A 399 -66.562 8.526 -49.280 1.00 61.93 C +ATOM 2445 CG MET A 399 -65.538 7.688 -50.064 1.00 64.95 C +ATOM 2446 SD MET A 399 -66.260 6.280 -50.941 1.00 68.46 S +ATOM 2447 CE MET A 399 -67.491 7.089 -51.963 1.00 62.77 C +ATOM 2448 N ALA A 400 -65.851 11.645 -49.719 1.00 40.73 N +ATOM 2449 CA ALA A 400 -65.136 12.686 -50.445 1.00 42.98 C +ATOM 2450 C ALA A 400 -64.183 13.425 -49.523 1.00 42.60 C +ATOM 2451 O ALA A 400 -63.014 13.639 -49.864 1.00 40.22 O +ATOM 2452 CB ALA A 400 -66.128 13.662 -51.078 1.00 43.23 C +ATOM 2453 N ILE A 401 -64.645 13.752 -48.317 1.00 42.57 N +ATOM 2454 CA ILE A 401 -63.796 14.451 -47.361 1.00 40.68 C +ATOM 2455 C ILE A 401 -62.569 13.611 -47.054 1.00 44.14 C +ATOM 2456 O ILE A 401 -61.430 14.091 -47.111 1.00 42.59 O +ATOM 2457 CB ILE A 401 -64.597 14.771 -46.088 1.00 38.00 C +ATOM 2458 CG1 ILE A 401 -65.764 15.701 -46.435 1.00 38.00 C +ATOM 2459 CG2 ILE A 401 -63.687 15.362 -45.024 1.00 38.00 C +ATOM 2460 CD1 ILE A 401 -66.682 16.018 -45.294 1.00 38.00 C +ATOM 2461 N PHE A 402 -62.788 12.322 -46.794 1.00 45.75 N +ATOM 2462 CA PHE A 402 -61.686 11.434 -46.453 1.00 45.97 C +ATOM 2463 C PHE A 402 -60.704 11.301 -47.611 1.00 50.57 C +ATOM 2464 O PHE A 402 -59.488 11.236 -47.398 1.00 50.07 O +ATOM 2465 CB PHE A 402 -62.243 10.073 -46.034 1.00 40.64 C +ATOM 2466 CG PHE A 402 -61.189 9.078 -45.681 1.00 44.73 C +ATOM 2467 CD1 PHE A 402 -60.359 9.295 -44.597 1.00 49.67 C +ATOM 2468 CD2 PHE A 402 -61.030 7.923 -46.424 1.00 47.71 C +ATOM 2469 CE1 PHE A 402 -59.379 8.383 -44.263 1.00 51.07 C +ATOM 2470 CE2 PHE A 402 -60.052 7.005 -46.099 1.00 50.81 C +ATOM 2471 CZ PHE A 402 -59.225 7.234 -45.014 1.00 50.70 C +ATOM 2472 N ASP A 403 -61.204 11.296 -48.848 1.00 52.62 N +ATOM 2473 CA ASP A 403 -60.301 11.195 -49.989 1.00 51.49 C +ATOM 2474 C ASP A 403 -59.555 12.499 -50.212 1.00 52.49 C +ATOM 2475 O ASP A 403 -58.367 12.487 -50.549 1.00 52.87 O +ATOM 2476 CB ASP A 403 -61.073 10.811 -51.245 1.00 51.38 C +ATOM 2477 CG ASP A 403 -61.527 9.380 -51.227 1.00 58.69 C +ATOM 2478 OD1 ASP A 403 -60.769 8.520 -50.729 1.00 54.86 O +ATOM 2479 OD2 ASP A 403 -62.657 9.126 -51.688 1.00 64.20 O +ATOM 2480 N PHE A 404 -60.230 13.634 -50.022 1.00 48.48 N +ATOM 2481 CA PHE A 404 -59.552 14.908 -50.224 1.00 52.04 C +ATOM 2482 C PHE A 404 -58.452 15.106 -49.192 1.00 48.14 C +ATOM 2483 O PHE A 404 -57.401 15.680 -49.500 1.00 48.51 O +ATOM 2484 CB PHE A 404 -60.550 16.065 -50.194 1.00 48.20 C +ATOM 2485 CG PHE A 404 -59.903 17.422 -50.285 1.00 50.16 C +ATOM 2486 CD1 PHE A 404 -59.061 17.732 -51.341 1.00 54.82 C +ATOM 2487 CD2 PHE A 404 -60.141 18.387 -49.323 1.00 55.09 C +ATOM 2488 CE1 PHE A 404 -58.457 18.972 -51.429 1.00 54.26 C +ATOM 2489 CE2 PHE A 404 -59.545 19.631 -49.405 1.00 54.79 C +ATOM 2490 CZ PHE A 404 -58.701 19.925 -50.462 1.00 57.29 C +ATOM 2491 N LEU A 405 -58.668 14.632 -47.966 1.00 38.00 N +ATOM 2492 CA LEU A 405 -57.625 14.740 -46.956 1.00 39.06 C +ATOM 2493 C LEU A 405 -56.370 13.980 -47.371 1.00 48.60 C +ATOM 2494 O LEU A 405 -55.250 14.462 -47.168 1.00 49.50 O +ATOM 2495 CB LEU A 405 -58.157 14.238 -45.620 1.00 38.03 C +ATOM 2496 CG LEU A 405 -59.081 15.263 -44.976 1.00 41.12 C +ATOM 2497 CD1 LEU A 405 -59.842 14.644 -43.841 1.00 47.39 C +ATOM 2498 CD2 LEU A 405 -58.224 16.407 -44.468 1.00 41.52 C +ATOM 2499 N ILE A 406 -56.534 12.806 -47.987 1.00 51.02 N +ATOM 2500 CA ILE A 406 -55.390 12.000 -48.411 1.00 45.81 C +ATOM 2501 C ILE A 406 -55.026 12.198 -49.874 1.00 46.16 C +ATOM 2502 O ILE A 406 -53.973 11.698 -50.303 1.00 47.33 O +ATOM 2503 CB ILE A 406 -55.634 10.503 -48.149 1.00 41.23 C +ATOM 2504 CG1 ILE A 406 -56.814 10.040 -48.991 1.00 49.15 C +ATOM 2505 CG2 ILE A 406 -55.861 10.249 -46.673 1.00 38.00 C +ATOM 2506 CD1 ILE A 406 -57.186 8.614 -48.756 1.00 63.49 C +ATOM 2507 N GLY A 407 -55.858 12.884 -50.653 1.00 49.63 N +ATOM 2508 CA GLY A 407 -55.593 13.078 -52.072 1.00 51.66 C +ATOM 2509 C GLY A 407 -55.788 11.831 -52.907 1.00 49.93 C +ATOM 2510 O GLY A 407 -54.985 11.554 -53.810 1.00 43.58 O +ATOM 2511 N ASN A 408 -56.865 11.094 -52.657 1.00 53.85 N +ATOM 2512 CA ASN A 408 -57.142 9.837 -53.347 1.00 57.16 C +ATOM 2513 C ASN A 408 -58.100 10.178 -54.482 1.00 55.90 C +ATOM 2514 O ASN A 408 -59.318 10.218 -54.306 1.00 55.74 O +ATOM 2515 CB ASN A 408 -57.735 8.803 -52.392 1.00 56.99 C +ATOM 2516 CG ASN A 408 -57.751 7.389 -52.970 1.00 54.34 C +ATOM 2517 OD1 ASN A 408 -56.788 6.950 -53.617 1.00 46.36 O +ATOM 2518 ND2 ASN A 408 -58.863 6.679 -52.761 1.00 47.37 N +ATOM 2519 N MET A 409 -57.535 10.463 -55.653 1.00 49.35 N +ATOM 2520 CA MET A 409 -58.377 10.728 -56.813 1.00 52.46 C +ATOM 2521 C MET A 409 -59.030 9.450 -57.323 1.00 54.97 C +ATOM 2522 O MET A 409 -60.097 9.501 -57.945 1.00 57.71 O +ATOM 2523 CB MET A 409 -57.547 11.390 -57.909 1.00 53.27 C +ATOM 2524 CG MET A 409 -56.578 12.425 -57.367 1.00 55.07 C +ATOM 2525 SD MET A 409 -55.739 13.369 -58.653 1.00 52.78 S +ATOM 2526 CE MET A 409 -54.443 14.179 -57.703 1.00 46.60 C +ATOM 2527 N ASP A 410 -58.411 8.303 -57.050 1.00 57.40 N +ATOM 2528 CA ASP A 410 -58.831 7.011 -57.594 1.00 53.57 C +ATOM 2529 C ASP A 410 -59.840 6.337 -56.659 1.00 50.64 C +ATOM 2530 O ASP A 410 -59.547 5.357 -55.973 1.00 58.48 O +ATOM 2531 CB ASP A 410 -57.603 6.138 -57.822 1.00 52.37 C +ATOM 2532 CG ASP A 410 -57.919 4.857 -58.556 1.00 62.39 C +ATOM 2533 OD1 ASP A 410 -59.103 4.629 -58.885 1.00 67.83 O +ATOM 2534 OD2 ASP A 410 -56.975 4.073 -58.799 1.00 57.73 O +ATOM 2535 N ARG A 411 -61.058 6.867 -56.656 1.00 43.42 N +ATOM 2536 CA ARG A 411 -62.172 6.253 -55.936 1.00 46.95 C +ATOM 2537 C ARG A 411 -63.320 6.019 -56.919 1.00 49.27 C +ATOM 2538 O ARG A 411 -64.387 6.637 -56.825 1.00 38.00 O +ATOM 2539 CB ARG A 411 -62.609 7.116 -54.739 1.00 49.83 C +ATOM 2540 CG ARG A 411 -63.634 6.423 -53.836 1.00 57.10 C +ATOM 2541 CD ARG A 411 -63.079 6.166 -52.446 1.00 53.53 C +ATOM 2542 NE ARG A 411 -62.091 5.096 -52.444 1.00 59.71 N +ATOM 2543 CZ ARG A 411 -61.317 4.800 -51.406 1.00 60.42 C +ATOM 2544 NH1 ARG A 411 -61.419 5.499 -50.283 1.00 56.38 N +ATOM 2545 NH2 ARG A 411 -60.442 3.805 -51.490 1.00 59.24 N +ATOM 2546 N HIS A 412 -63.102 5.084 -57.850 1.00 57.09 N +ATOM 2547 CA HIS A 412 -64.112 4.777 -58.860 1.00 62.21 C +ATOM 2548 C HIS A 412 -65.296 4.009 -58.281 1.00 58.93 C +ATOM 2549 O HIS A 412 -66.430 4.174 -58.748 1.00 53.00 O +ATOM 2550 CB HIS A 412 -63.481 3.990 -60.018 1.00 64.84 C +ATOM 2551 CG HIS A 412 -62.461 2.972 -59.597 1.00 64.93 C +ATOM 2552 ND1 HIS A 412 -62.454 2.383 -58.350 1.00 62.56 N +ATOM 2553 CD2 HIS A 412 -61.413 2.437 -60.270 1.00 66.71 C +ATOM 2554 CE1 HIS A 412 -61.442 1.536 -58.271 1.00 69.94 C +ATOM 2555 NE2 HIS A 412 -60.796 1.549 -59.423 1.00 66.39 N +ATOM 2556 N HIS A 413 -65.063 3.166 -57.280 1.00 59.28 N +ATOM 2557 CA HIS A 413 -66.124 2.357 -56.706 1.00 54.73 C +ATOM 2558 C HIS A 413 -65.990 2.331 -55.193 1.00 47.76 C +ATOM 2559 O HIS A 413 -64.880 2.274 -54.655 1.00 39.43 O +ATOM 2560 CB HIS A 413 -66.090 0.934 -57.260 1.00 60.35 C +ATOM 2561 CG HIS A 413 -66.375 0.856 -58.726 1.00 58.72 C +ATOM 2562 ND1 HIS A 413 -65.468 1.267 -59.678 1.00 52.99 N +ATOM 2563 CD2 HIS A 413 -67.458 0.409 -59.404 1.00 62.45 C +ATOM 2564 CE1 HIS A 413 -65.983 1.082 -60.880 1.00 63.70 C +ATOM 2565 NE2 HIS A 413 -67.190 0.563 -60.742 1.00 68.79 N +ATOM 2566 N TYR A 414 -67.128 2.370 -54.516 1.00 45.89 N +ATOM 2567 CA TYR A 414 -67.193 2.207 -53.075 1.00 46.07 C +ATOM 2568 C TYR A 414 -68.048 0.991 -52.753 1.00 52.84 C +ATOM 2569 O TYR A 414 -69.128 0.816 -53.325 1.00 55.61 O +ATOM 2570 CB TYR A 414 -67.766 3.458 -52.415 1.00 47.13 C +ATOM 2571 CG TYR A 414 -69.184 3.794 -52.821 1.00 42.18 C +ATOM 2572 CD1 TYR A 414 -69.446 4.596 -53.922 1.00 47.22 C +ATOM 2573 CD2 TYR A 414 -70.260 3.315 -52.095 1.00 47.87 C +ATOM 2574 CE1 TYR A 414 -70.745 4.905 -54.287 1.00 50.97 C +ATOM 2575 CE2 TYR A 414 -71.554 3.614 -52.452 1.00 53.48 C +ATOM 2576 CZ TYR A 414 -71.794 4.409 -53.545 1.00 52.93 C +ATOM 2577 OH TYR A 414 -73.095 4.702 -53.885 1.00 54.99 O +ATOM 2578 N GLU A 415 -67.578 0.159 -51.829 1.00 46.32 N +ATOM 2579 CA GLU A 415 -68.267 -1.079 -51.497 1.00 46.56 C +ATOM 2580 C GLU A 415 -69.153 -0.896 -50.274 1.00 44.48 C +ATOM 2581 O GLU A 415 -68.906 -0.034 -49.427 1.00 46.30 O +ATOM 2582 CB GLU A 415 -67.273 -2.213 -51.258 1.00 47.67 C +ATOM 2583 CG GLU A 415 -66.537 -2.642 -52.511 1.00 53.18 C +ATOM 2584 CD GLU A 415 -65.771 -3.933 -52.315 1.00 61.84 C +ATOM 2585 OE1 GLU A 415 -65.996 -4.608 -51.287 1.00 59.19 O +ATOM 2586 OE2 GLU A 415 -64.935 -4.266 -53.182 1.00 64.63 O +ATOM 2587 N MET A 416 -70.201 -1.715 -50.201 1.00 47.76 N +ATOM 2588 CA MET A 416 -71.171 -1.667 -49.117 1.00 49.40 C +ATOM 2589 C MET A 416 -71.517 -3.081 -48.678 1.00 53.17 C +ATOM 2590 O MET A 416 -71.401 -4.030 -49.456 1.00 60.85 O +ATOM 2591 CB MET A 416 -72.458 -0.958 -49.542 1.00 39.99 C +ATOM 2592 CG MET A 416 -72.253 0.412 -50.127 1.00 39.05 C +ATOM 2593 SD MET A 416 -73.837 1.169 -50.494 1.00 54.73 S +ATOM 2594 CE MET A 416 -74.700 0.904 -48.947 1.00 56.78 C +ATOM 2595 N PHE A 417 -71.942 -3.218 -47.422 1.00 51.38 N +ATOM 2596 CA PHE A 417 -72.475 -4.481 -46.922 1.00 53.31 C +ATOM 2597 C PHE A 417 -73.971 -4.529 -47.219 1.00 59.23 C +ATOM 2598 O PHE A 417 -74.724 -3.644 -46.791 1.00 57.25 O +ATOM 2599 CB PHE A 417 -72.209 -4.646 -45.428 1.00 48.31 C +ATOM 2600 CG PHE A 417 -70.775 -4.916 -45.099 1.00 45.82 C +ATOM 2601 CD1 PHE A 417 -70.177 -6.102 -45.480 1.00 51.35 C +ATOM 2602 CD2 PHE A 417 -70.024 -3.988 -44.398 1.00 51.27 C +ATOM 2603 CE1 PHE A 417 -68.848 -6.357 -45.176 1.00 59.50 C +ATOM 2604 CE2 PHE A 417 -68.697 -4.236 -44.085 1.00 50.64 C +ATOM 2605 CZ PHE A 417 -68.107 -5.422 -44.477 1.00 53.87 C +ATOM 2606 N THR A 418 -74.398 -5.562 -47.952 1.00 60.23 N +ATOM 2607 CA THR A 418 -75.780 -5.638 -48.414 1.00 63.54 C +ATOM 2608 C THR A 418 -76.783 -5.775 -47.270 1.00 56.25 C +ATOM 2609 O THR A 418 -77.951 -5.412 -47.445 1.00 55.76 O +ATOM 2610 CB THR A 418 -75.939 -6.793 -49.415 1.00 54.51 C +ATOM 2611 OG1 THR A 418 -77.328 -6.994 -49.700 1.00 50.27 O +ATOM 2612 CG2 THR A 418 -75.361 -8.075 -48.870 1.00 51.14 C +ATOM 2613 N LYS A 419 -76.355 -6.272 -46.107 1.00 54.77 N +ATOM 2614 CA LYS A 419 -77.274 -6.450 -44.985 1.00 57.55 C +ATOM 2615 C LYS A 419 -77.784 -5.121 -44.444 1.00 64.94 C +ATOM 2616 O LYS A 419 -78.909 -5.049 -43.931 1.00 65.16 O +ATOM 2617 CB LYS A 419 -76.583 -7.234 -43.869 1.00 54.21 C +ATOM 2618 CG LYS A 419 -77.426 -7.415 -42.623 1.00 57.38 C +ATOM 2619 CD LYS A 419 -76.785 -8.385 -41.658 1.00 55.58 C +ATOM 2620 CE LYS A 419 -77.603 -8.512 -40.387 1.00 60.71 C +ATOM 2621 NZ LYS A 419 -77.035 -9.536 -39.479 1.00 65.03 N +ATOM 2622 N PHE A 420 -76.987 -4.063 -44.563 1.00 65.11 N +ATOM 2623 CA PHE A 420 -77.298 -2.782 -43.946 1.00 68.22 C +ATOM 2624 C PHE A 420 -78.156 -1.874 -44.819 1.00 70.04 C +ATOM 2625 O PHE A 420 -78.619 -0.835 -44.333 1.00 73.25 O +ATOM 2626 CB PHE A 420 -75.998 -2.076 -43.560 1.00 70.29 C +ATOM 2627 CG PHE A 420 -75.203 -2.817 -42.524 1.00 63.58 C +ATOM 2628 CD1 PHE A 420 -75.844 -3.559 -41.543 1.00 54.36 C +ATOM 2629 CD2 PHE A 420 -73.818 -2.789 -42.539 1.00 63.19 C +ATOM 2630 CE1 PHE A 420 -75.120 -4.242 -40.591 1.00 59.85 C +ATOM 2631 CE2 PHE A 420 -73.087 -3.473 -41.588 1.00 57.65 C +ATOM 2632 CZ PHE A 420 -73.739 -4.200 -40.612 1.00 60.71 C +ATOM 2633 N GLY A 421 -78.364 -2.218 -46.085 1.00 63.56 N +ATOM 2634 CA GLY A 421 -79.300 -1.482 -46.904 1.00 62.06 C +ATOM 2635 C GLY A 421 -78.701 -0.218 -47.495 1.00 72.48 C +ATOM 2636 O GLY A 421 -77.499 0.051 -47.406 1.00 76.89 O +ATOM 2637 N ASP A 422 -79.585 0.577 -48.109 1.00 72.59 N +ATOM 2638 CA ASP A 422 -79.155 1.791 -48.800 1.00 72.53 C +ATOM 2639 C ASP A 422 -78.537 2.806 -47.849 1.00 69.20 C +ATOM 2640 O ASP A 422 -77.668 3.587 -48.256 1.00 70.69 O +ATOM 2641 CB ASP A 422 -80.332 2.406 -49.556 1.00 70.99 C +ATOM 2642 CG ASP A 422 -81.098 1.376 -50.372 1.00 83.81 C +ATOM 2643 OD1 ASP A 422 -81.844 0.569 -49.777 1.00 79.04 O +ATOM 2644 OD2 ASP A 422 -80.936 1.361 -51.612 1.00 87.23 O +ATOM 2645 N ASP A 423 -78.948 2.802 -46.584 1.00 67.82 N +ATOM 2646 CA ASP A 423 -78.406 3.724 -45.596 1.00 67.85 C +ATOM 2647 C ASP A 423 -77.113 3.222 -44.972 1.00 66.09 C +ATOM 2648 O ASP A 423 -76.544 3.908 -44.118 1.00 67.97 O +ATOM 2649 CB ASP A 423 -79.438 3.984 -44.493 1.00 61.77 C +ATOM 2650 CG ASP A 423 -80.659 4.719 -45.001 1.00 65.76 C +ATOM 2651 OD1 ASP A 423 -80.554 5.400 -46.042 1.00 75.92 O +ATOM 2652 OD2 ASP A 423 -81.726 4.612 -44.361 1.00 63.94 O +ATOM 2653 N GLY A 424 -76.629 2.058 -45.392 1.00 69.17 N +ATOM 2654 CA GLY A 424 -75.415 1.518 -44.820 1.00 67.76 C +ATOM 2655 C GLY A 424 -74.204 2.381 -45.108 1.00 59.84 C +ATOM 2656 O GLY A 424 -74.158 3.161 -46.063 1.00 52.26 O +ATOM 2657 N PHE A 425 -73.214 2.243 -44.230 1.00 55.53 N +ATOM 2658 CA PHE A 425 -71.974 2.980 -44.378 1.00 52.29 C +ATOM 2659 C PHE A 425 -71.158 2.411 -45.529 1.00 51.97 C +ATOM 2660 O PHE A 425 -71.357 1.276 -45.971 1.00 49.95 O +ATOM 2661 CB PHE A 425 -71.157 2.932 -43.087 1.00 54.64 C +ATOM 2662 CG PHE A 425 -70.662 1.551 -42.713 1.00 54.49 C +ATOM 2663 CD1 PHE A 425 -71.507 0.639 -42.094 1.00 50.77 C +ATOM 2664 CD2 PHE A 425 -69.337 1.188 -42.928 1.00 46.60 C +ATOM 2665 CE1 PHE A 425 -71.050 -0.617 -41.730 1.00 48.48 C +ATOM 2666 CE2 PHE A 425 -68.876 -0.065 -42.560 1.00 42.62 C +ATOM 2667 CZ PHE A 425 -69.733 -0.967 -41.962 1.00 46.85 C +ATOM 2668 N LEU A 426 -70.203 3.204 -45.992 1.00 54.11 N +ATOM 2669 CA LEU A 426 -69.364 2.834 -47.118 1.00 47.10 C +ATOM 2670 C LEU A 426 -68.017 2.341 -46.618 1.00 45.11 C +ATOM 2671 O LEU A 426 -67.495 2.840 -45.619 1.00 52.68 O +ATOM 2672 CB LEU A 426 -69.161 4.018 -48.057 1.00 49.27 C +ATOM 2673 CG LEU A 426 -70.408 4.834 -48.388 1.00 52.95 C +ATOM 2674 CD1 LEU A 426 -70.066 5.814 -49.498 1.00 56.54 C +ATOM 2675 CD2 LEU A 426 -71.598 3.955 -48.762 1.00 47.16 C +ATOM 2676 N ILE A 427 -67.472 1.345 -47.301 1.00 38.00 N +ATOM 2677 CA ILE A 427 -66.166 0.791 -46.974 1.00 44.19 C +ATOM 2678 C ILE A 427 -65.120 1.465 -47.850 1.00 42.58 C +ATOM 2679 O ILE A 427 -65.243 1.476 -49.080 1.00 46.83 O +ATOM 2680 CB ILE A 427 -66.153 -0.735 -47.159 1.00 45.87 C +ATOM 2681 CG1 ILE A 427 -67.516 -1.316 -46.790 1.00 40.30 C +ATOM 2682 CG2 ILE A 427 -65.063 -1.389 -46.330 1.00 42.85 C +ATOM 2683 CD1 ILE A 427 -67.596 -2.791 -47.020 1.00 46.70 C +ATOM 2684 N HIS A 428 -64.080 2.009 -47.224 1.00 38.00 N +ATOM 2685 CA HIS A 428 -63.017 2.693 -47.951 1.00 43.42 C +ATOM 2686 C HIS A 428 -61.836 1.726 -48.029 1.00 47.76 C +ATOM 2687 O HIS A 428 -60.898 1.776 -47.233 1.00 48.26 O +ATOM 2688 CB HIS A 428 -62.646 4.010 -47.265 1.00 53.49 C +ATOM 2689 CG HIS A 428 -63.820 4.883 -46.917 1.00 56.83 C +ATOM 2690 ND1 HIS A 428 -63.725 5.935 -46.028 1.00 48.23 N +ATOM 2691 CD2 HIS A 428 -65.111 4.860 -47.330 1.00 53.34 C +ATOM 2692 CE1 HIS A 428 -64.904 6.521 -45.911 1.00 48.78 C +ATOM 2693 NE2 HIS A 428 -65.763 5.888 -46.690 1.00 48.26 N +ATOM 2694 N LEU A 429 -61.892 0.832 -49.021 1.00 51.14 N +ATOM 2695 CA LEU A 429 -60.998 -0.330 -49.045 1.00 54.76 C +ATOM 2696 C LEU A 429 -59.578 0.015 -49.478 1.00 59.07 C +ATOM 2697 O LEU A 429 -58.633 -0.095 -48.691 1.00 63.74 O +ATOM 2698 CB LEU A 429 -61.566 -1.423 -49.955 1.00 52.99 C +ATOM 2699 CG LEU A 429 -62.573 -2.377 -49.323 1.00 55.16 C +ATOM 2700 CD1 LEU A 429 -62.944 -3.481 -50.295 1.00 62.22 C +ATOM 2701 CD2 LEU A 429 -61.989 -2.972 -48.056 1.00 56.71 C +ATOM 2702 N ASP A 430 -59.403 0.401 -50.733 1.00 56.28 N +ATOM 2703 CA ASP A 430 -58.069 0.560 -51.307 1.00 66.50 C +ATOM 2704 C ASP A 430 -57.745 2.047 -51.350 1.00 55.01 C +ATOM 2705 O ASP A 430 -58.238 2.778 -52.211 1.00 55.25 O +ATOM 2706 CB ASP A 430 -57.977 -0.102 -52.681 1.00 81.37 C +ATOM 2707 CG ASP A 430 -57.905 -1.642 -52.599 1.00 80.02 C +ATOM 2708 OD1 ASP A 430 -56.937 -2.173 -51.999 1.00 69.59 O +ATOM 2709 OD2 ASP A 430 -58.809 -2.321 -53.144 1.00 84.87 O +ATOM 2710 N ASN A 431 -56.937 2.495 -50.388 1.00 56.37 N +ATOM 2711 CA ASN A 431 -56.524 3.887 -50.276 1.00 51.70 C +ATOM 2712 C ASN A 431 -55.053 4.089 -50.602 1.00 41.66 C +ATOM 2713 O ASN A 431 -54.515 5.165 -50.331 1.00 41.41 O +ATOM 2714 CB ASN A 431 -56.804 4.398 -48.863 1.00 50.17 C +ATOM 2715 CG ASN A 431 -58.087 3.833 -48.289 1.00 57.65 C +ATOM 2716 OD1 ASN A 431 -59.186 4.167 -48.738 1.00 54.56 O +ATOM 2717 ND2 ASN A 431 -57.953 2.966 -47.289 1.00 56.20 N +ATOM 2718 N ALA A 432 -54.399 3.088 -51.193 1.00 44.88 N +ATOM 2719 CA ALA A 432 -52.951 3.086 -51.372 1.00 48.54 C +ATOM 2720 C ALA A 432 -52.440 4.169 -52.315 1.00 50.61 C +ATOM 2721 O ALA A 432 -51.223 4.238 -52.524 1.00 45.95 O +ATOM 2722 CB ALA A 432 -52.481 1.724 -51.871 1.00 54.97 C +ATOM 2723 N ARG A 433 -53.320 4.967 -52.928 1.00 57.43 N +ATOM 2724 CA ARG A 433 -52.894 5.986 -53.885 1.00 60.99 C +ATOM 2725 C ARG A 433 -52.774 7.376 -53.282 1.00 56.20 C +ATOM 2726 O ARG A 433 -51.950 8.172 -53.749 1.00 50.96 O +ATOM 2727 CB ARG A 433 -53.854 6.045 -55.080 1.00 56.10 C +ATOM 2728 CG ARG A 433 -53.842 4.785 -55.929 1.00 55.84 C +ATOM 2729 CD ARG A 433 -53.864 5.097 -57.420 1.00 51.87 C +ATOM 2730 NE ARG A 433 -54.051 3.895 -58.234 1.00 56.02 N +ATOM 2731 CZ ARG A 433 -53.421 3.658 -59.383 1.00 54.90 C +ATOM 2732 NH1 ARG A 433 -52.544 4.530 -59.858 1.00 50.61 N +ATOM 2733 NH2 ARG A 433 -53.653 2.538 -60.056 1.00 59.27 N +ATOM 2734 N GLY A 434 -53.539 7.674 -52.238 1.00 51.72 N +ATOM 2735 CA GLY A 434 -53.428 8.948 -51.560 1.00 46.60 C +ATOM 2736 C GLY A 434 -52.044 9.205 -51.000 1.00 45.35 C +ATOM 2737 O GLY A 434 -51.136 8.379 -51.146 1.00 42.32 O +ATOM 2738 N PHE A 435 -51.861 10.381 -50.402 1.00 51.20 N +ATOM 2739 CA PHE A 435 -50.593 10.760 -49.781 1.00 49.07 C +ATOM 2740 C PHE A 435 -49.454 10.658 -50.788 1.00 45.40 C +ATOM 2741 O PHE A 435 -48.430 10.015 -50.548 1.00 43.18 O +ATOM 2742 CB PHE A 435 -50.308 9.913 -48.539 1.00 45.24 C +ATOM 2743 CG PHE A 435 -51.134 10.296 -47.352 1.00 43.06 C +ATOM 2744 CD1 PHE A 435 -51.162 11.605 -46.909 1.00 48.73 C +ATOM 2745 CD2 PHE A 435 -51.909 9.357 -46.703 1.00 38.00 C +ATOM 2746 CE1 PHE A 435 -51.931 11.960 -45.821 1.00 48.97 C +ATOM 2747 CE2 PHE A 435 -52.678 9.708 -45.621 1.00 38.00 C +ATOM 2748 CZ PHE A 435 -52.692 11.009 -45.179 1.00 38.00 C +ATOM 2749 N GLY A 436 -49.659 11.276 -51.943 1.00 44.34 N +ATOM 2750 CA GLY A 436 -48.637 11.283 -52.962 1.00 46.77 C +ATOM 2751 C GLY A 436 -48.201 12.676 -53.358 1.00 46.69 C +ATOM 2752 O GLY A 436 -47.110 12.858 -53.901 1.00 42.74 O +ATOM 2753 N ARG A 437 -49.034 13.673 -53.072 1.00 49.59 N +ATOM 2754 CA ARG A 437 -48.734 15.069 -53.385 1.00 49.48 C +ATOM 2755 C ARG A 437 -48.930 15.881 -52.109 1.00 49.56 C +ATOM 2756 O ARG A 437 -50.059 16.230 -51.748 1.00 49.11 O +ATOM 2757 CB ARG A 437 -49.618 15.591 -54.516 1.00 57.35 C +ATOM 2758 CG ARG A 437 -49.385 14.936 -55.869 1.00 56.69 C +ATOM 2759 CD ARG A 437 -48.029 15.347 -56.430 1.00 65.52 C +ATOM 2760 NE ARG A 437 -47.904 16.795 -56.599 1.00 73.17 N +ATOM 2761 CZ ARG A 437 -48.259 17.458 -57.696 1.00 77.21 C +ATOM 2762 NH1 ARG A 437 -48.768 16.805 -58.735 1.00 70.09 N +ATOM 2763 NH2 ARG A 437 -48.106 18.776 -57.755 1.00 75.57 N +ATOM 2764 N HIS A 438 -47.835 16.175 -51.419 1.00 46.13 N +ATOM 2765 CA HIS A 438 -47.925 17.003 -50.227 1.00 47.24 C +ATOM 2766 C HIS A 438 -47.914 18.487 -50.550 1.00 51.37 C +ATOM 2767 O HIS A 438 -48.254 19.299 -49.683 1.00 54.28 O +ATOM 2768 CB HIS A 438 -46.785 16.659 -49.273 1.00 46.57 C +ATOM 2769 CG HIS A 438 -45.424 16.904 -49.841 1.00 40.46 C +ATOM 2770 ND1 HIS A 438 -44.911 18.169 -50.026 1.00 38.47 N +ATOM 2771 CD2 HIS A 438 -44.473 16.044 -50.275 1.00 41.14 C +ATOM 2772 CE1 HIS A 438 -43.697 18.078 -50.536 1.00 47.02 C +ATOM 2773 NE2 HIS A 438 -43.408 16.799 -50.700 1.00 45.86 N +ATOM 2774 N SER A 439 -47.537 18.851 -51.771 1.00 55.66 N +ATOM 2775 CA SER A 439 -47.472 20.239 -52.194 1.00 55.42 C +ATOM 2776 C SER A 439 -48.686 20.664 -53.010 1.00 57.69 C +ATOM 2777 O SER A 439 -48.834 21.854 -53.300 1.00 67.27 O +ATOM 2778 CB SER A 439 -46.183 20.464 -52.999 1.00 58.38 C +ATOM 2779 OG SER A 439 -46.115 21.769 -53.539 1.00 81.37 O +ATOM 2780 N HIS A 440 -49.562 19.733 -53.369 1.00 52.72 N +ATOM 2781 CA HIS A 440 -50.733 20.020 -54.182 1.00 49.19 C +ATOM 2782 C HIS A 440 -51.985 19.499 -53.495 1.00 45.33 C +ATOM 2783 O HIS A 440 -51.968 18.432 -52.875 1.00 50.24 O +ATOM 2784 CB HIS A 440 -50.607 19.398 -55.572 1.00 59.23 C +ATOM 2785 CG HIS A 440 -51.813 19.601 -56.434 1.00 66.28 C +ATOM 2786 ND1 HIS A 440 -52.287 20.850 -56.772 1.00 69.91 N +ATOM 2787 CD2 HIS A 440 -52.658 18.710 -57.007 1.00 65.59 C +ATOM 2788 CE1 HIS A 440 -53.363 20.719 -57.528 1.00 68.15 C +ATOM 2789 NE2 HIS A 440 -53.611 19.431 -57.683 1.00 62.74 N +ATOM 2790 N ASP A 441 -53.065 20.264 -53.594 1.00 41.54 N +ATOM 2791 CA ASP A 441 -54.366 19.861 -53.081 1.00 44.28 C +ATOM 2792 C ASP A 441 -55.320 19.798 -54.261 1.00 46.87 C +ATOM 2793 O ASP A 441 -55.489 20.791 -54.975 1.00 53.10 O +ATOM 2794 CB ASP A 441 -54.879 20.839 -52.022 1.00 50.36 C +ATOM 2795 CG ASP A 441 -53.894 21.040 -50.876 1.00 56.57 C +ATOM 2796 OD1 ASP A 441 -53.002 20.184 -50.678 1.00 59.01 O +ATOM 2797 OD2 ASP A 441 -54.018 22.065 -50.171 1.00 52.84 O +ATOM 2798 N GLU A 442 -55.900 18.629 -54.498 1.00 48.10 N +ATOM 2799 CA GLU A 442 -56.802 18.445 -55.632 1.00 51.14 C +ATOM 2800 C GLU A 442 -58.231 18.707 -55.172 1.00 47.67 C +ATOM 2801 O GLU A 442 -58.870 17.845 -54.565 1.00 45.35 O +ATOM 2802 CB GLU A 442 -56.640 17.053 -56.227 1.00 56.53 C +ATOM 2803 CG GLU A 442 -57.382 16.860 -57.541 1.00 61.21 C +ATOM 2804 CD GLU A 442 -56.967 17.847 -58.616 1.00 54.94 C +ATOM 2805 OE1 GLU A 442 -57.825 18.640 -59.052 1.00 49.70 O +ATOM 2806 OE2 GLU A 442 -55.782 17.843 -59.012 1.00 56.99 O +ATOM 2807 N ILE A 443 -58.745 19.898 -55.491 1.00 50.88 N +ATOM 2808 CA ILE A 443 -60.067 20.299 -55.021 1.00 49.82 C +ATOM 2809 C ILE A 443 -61.178 19.594 -55.781 1.00 48.46 C +ATOM 2810 O ILE A 443 -62.326 19.583 -55.318 1.00 43.67 O +ATOM 2811 CB ILE A 443 -60.272 21.819 -55.135 1.00 48.08 C +ATOM 2812 CG1 ILE A 443 -58.959 22.570 -54.888 1.00 50.36 C +ATOM 2813 CG2 ILE A 443 -61.353 22.282 -54.169 1.00 38.00 C +ATOM 2814 CD1 ILE A 443 -58.219 22.989 -56.162 1.00 47.84 C +ATOM 2815 N SER A 444 -60.876 19.023 -56.948 1.00 48.30 N +ATOM 2816 CA SER A 444 -61.898 18.285 -57.672 1.00 50.94 C +ATOM 2817 C SER A 444 -62.389 17.082 -56.881 1.00 50.45 C +ATOM 2818 O SER A 444 -63.536 16.661 -57.066 1.00 51.01 O +ATOM 2819 CB SER A 444 -61.366 17.849 -59.042 1.00 56.94 C +ATOM 2820 OG SER A 444 -60.175 17.092 -58.923 1.00 55.57 O +ATOM 2821 N ILE A 445 -61.567 16.543 -55.975 1.00 46.82 N +ATOM 2822 CA ILE A 445 -62.037 15.460 -55.117 1.00 47.59 C +ATOM 2823 C ILE A 445 -63.162 15.950 -54.226 1.00 45.06 C +ATOM 2824 O ILE A 445 -64.122 15.219 -53.956 1.00 44.50 O +ATOM 2825 CB ILE A 445 -60.877 14.879 -54.287 1.00 44.65 C +ATOM 2826 CG1 ILE A 445 -59.688 14.553 -55.182 1.00 43.66 C +ATOM 2827 CG2 ILE A 445 -61.312 13.623 -53.564 1.00 50.43 C +ATOM 2828 CD1 ILE A 445 -58.475 14.113 -54.408 1.00 45.98 C +ATOM 2829 N LEU A 446 -63.087 17.201 -53.793 1.00 47.16 N +ATOM 2830 CA LEU A 446 -64.085 17.802 -52.925 1.00 51.45 C +ATOM 2831 C LEU A 446 -65.346 18.210 -53.678 1.00 47.72 C +ATOM 2832 O LEU A 446 -66.243 18.804 -53.073 1.00 45.56 O +ATOM 2833 CB LEU A 446 -63.468 19.013 -52.216 1.00 55.10 C +ATOM 2834 CG LEU A 446 -63.570 19.179 -50.698 1.00 47.40 C +ATOM 2835 CD1 LEU A 446 -64.848 19.902 -50.344 1.00 57.60 C +ATOM 2836 CD2 LEU A 446 -63.525 17.849 -50.004 1.00 40.60 C +ATOM 2837 N SER A 447 -65.443 17.873 -54.964 1.00 49.10 N +ATOM 2838 CA SER A 447 -66.608 18.252 -55.760 1.00 55.79 C +ATOM 2839 C SER A 447 -67.948 17.854 -55.151 1.00 57.54 C +ATOM 2840 O SER A 447 -68.902 18.640 -55.285 1.00 58.96 O +ATOM 2841 CB SER A 447 -66.499 17.656 -57.173 1.00 51.26 C +ATOM 2842 OG SER A 447 -65.503 18.311 -57.935 1.00 52.26 O +ATOM 2843 N PRO A 448 -68.112 16.685 -54.513 1.00 53.97 N +ATOM 2844 CA PRO A 448 -69.426 16.381 -53.913 1.00 49.30 C +ATOM 2845 C PRO A 448 -69.868 17.420 -52.902 1.00 51.46 C +ATOM 2846 O PRO A 448 -71.022 17.867 -52.929 1.00 47.95 O +ATOM 2847 CB PRO A 448 -69.201 15.009 -53.267 1.00 51.03 C +ATOM 2848 CG PRO A 448 -68.118 14.397 -54.061 1.00 56.34 C +ATOM 2849 CD PRO A 448 -67.200 15.530 -54.413 1.00 51.97 C +ATOM 2850 N LEU A 449 -68.974 17.805 -51.990 1.00 57.47 N +ATOM 2851 CA LEU A 449 -69.312 18.837 -51.020 1.00 54.99 C +ATOM 2852 C LEU A 449 -69.450 20.195 -51.692 1.00 54.85 C +ATOM 2853 O LEU A 449 -70.334 20.980 -51.326 1.00 54.34 O +ATOM 2854 CB LEU A 449 -68.244 18.887 -49.929 1.00 42.74 C +ATOM 2855 CG LEU A 449 -68.528 19.800 -48.741 1.00 41.42 C +ATOM 2856 CD1 LEU A 449 -69.791 19.335 -48.025 1.00 42.56 C +ATOM 2857 CD2 LEU A 449 -67.342 19.838 -47.795 1.00 38.48 C +ATOM 2858 N SER A 450 -68.625 20.460 -52.710 1.00 54.71 N +ATOM 2859 CA SER A 450 -68.679 21.743 -53.400 1.00 52.20 C +ATOM 2860 C SER A 450 -70.026 21.943 -54.077 1.00 54.74 C +ATOM 2861 O SER A 450 -70.625 23.021 -53.982 1.00 62.20 O +ATOM 2862 CB SER A 450 -67.557 21.833 -54.438 1.00 50.58 C +ATOM 2863 OG SER A 450 -66.280 21.618 -53.862 1.00 49.56 O +ATOM 2864 N GLN A 451 -70.528 20.910 -54.747 1.00 58.73 N +ATOM 2865 CA GLN A 451 -71.709 21.056 -55.586 1.00 59.08 C +ATOM 2866 C GLN A 451 -73.002 20.718 -54.852 1.00 54.11 C +ATOM 2867 O GLN A 451 -73.985 21.453 -54.982 1.00 49.55 O +ATOM 2868 CB GLN A 451 -71.540 20.199 -56.843 1.00 58.13 C +ATOM 2869 CG GLN A 451 -70.217 20.500 -57.557 1.00 55.84 C +ATOM 2870 CD GLN A 451 -69.911 19.555 -58.696 1.00 60.59 C +ATOM 2871 OE1 GLN A 451 -70.128 18.350 -58.596 1.00 59.98 O +ATOM 2872 NE2 GLN A 451 -69.386 20.102 -59.789 1.00 62.29 N +ATOM 2873 N CYS A 452 -73.022 19.642 -54.060 1.00 62.01 N +ATOM 2874 CA CYS A 452 -74.238 19.306 -53.319 1.00 65.27 C +ATOM 2875 C CYS A 452 -74.488 20.290 -52.193 1.00 65.96 C +ATOM 2876 O CYS A 452 -75.641 20.649 -51.917 1.00 56.84 O +ATOM 2877 CB CYS A 452 -74.146 17.897 -52.745 1.00 62.77 C +ATOM 2878 SG CYS A 452 -73.911 16.639 -53.977 1.00 75.24 S +ATOM 2879 N CYS A 453 -73.419 20.719 -51.529 1.00 68.62 N +ATOM 2880 CA CYS A 453 -73.471 21.649 -50.409 1.00 68.29 C +ATOM 2881 C CYS A 453 -74.426 21.134 -49.324 1.00 67.03 C +ATOM 2882 O CYS A 453 -75.521 21.651 -49.102 1.00 62.57 O +ATOM 2883 CB CYS A 453 -73.834 23.057 -50.901 1.00 65.97 C +ATOM 2884 SG CYS A 453 -73.811 24.338 -49.611 1.00105.53 S +ATOM 2885 N MET A 454 -73.979 20.047 -48.686 1.00 62.40 N +ATOM 2886 CA MET A 454 -74.597 19.514 -47.474 1.00 61.18 C +ATOM 2887 C MET A 454 -73.675 18.491 -46.819 1.00 59.44 C +ATOM 2888 O MET A 454 -73.097 17.643 -47.504 1.00 59.14 O +ATOM 2889 CB MET A 454 -75.974 18.900 -47.761 1.00 62.02 C +ATOM 2890 CG MET A 454 -76.054 17.982 -48.960 1.00 60.59 C +ATOM 2891 SD MET A 454 -77.770 17.621 -49.416 1.00 74.57 S +ATOM 2892 CE MET A 454 -78.513 17.253 -47.832 1.00 52.98 C +ATOM 2893 N ILE A 455 -73.508 18.584 -45.496 1.00 63.05 N +ATOM 2894 CA ILE A 455 -72.596 17.732 -44.738 1.00 55.11 C +ATOM 2895 C ILE A 455 -73.297 17.279 -43.461 1.00 57.47 C +ATOM 2896 O ILE A 455 -74.163 17.979 -42.926 1.00 57.35 O +ATOM 2897 CB ILE A 455 -71.267 18.456 -44.415 1.00 45.40 C +ATOM 2898 CG1 ILE A 455 -70.288 17.517 -43.717 1.00 39.22 C +ATOM 2899 CG2 ILE A 455 -71.506 19.678 -43.552 1.00 48.46 C +ATOM 2900 CD1 ILE A 455 -68.991 18.181 -43.338 1.00 40.29 C +ATOM 2901 N LYS A 456 -72.931 16.088 -42.984 1.00 57.72 N +ATOM 2902 CA LYS A 456 -73.538 15.534 -41.780 1.00 54.96 C +ATOM 2903 C LYS A 456 -73.123 16.313 -40.534 1.00 52.72 C +ATOM 2904 O LYS A 456 -71.985 16.775 -40.408 1.00 49.72 O +ATOM 2905 CB LYS A 456 -73.159 14.063 -41.612 1.00 51.09 C +ATOM 2906 CG LYS A 456 -73.283 13.243 -42.882 1.00 60.67 C +ATOM 2907 CD LYS A 456 -73.583 11.773 -42.589 1.00 64.05 C +ATOM 2908 CE LYS A 456 -72.488 11.104 -41.777 1.00 60.35 C +ATOM 2909 NZ LYS A 456 -72.669 9.623 -41.741 1.00 54.96 N +ATOM 2910 N LYS A 457 -74.055 16.403 -39.581 1.00 55.20 N +ATOM 2911 CA LYS A 457 -73.799 17.145 -38.349 1.00 52.85 C +ATOM 2912 C LYS A 457 -72.564 16.610 -37.639 1.00 45.84 C +ATOM 2913 O LYS A 457 -71.623 17.360 -37.359 1.00 41.94 O +ATOM 2914 CB LYS A 457 -75.020 17.051 -37.430 1.00 59.04 C +ATOM 2915 CG LYS A 457 -74.928 17.832 -36.123 1.00 51.88 C +ATOM 2916 CD LYS A 457 -75.270 19.293 -36.332 1.00 54.26 C +ATOM 2917 CE LYS A 457 -75.831 19.927 -35.070 1.00 54.83 C +ATOM 2918 NZ LYS A 457 -76.266 21.330 -35.337 1.00 53.20 N +ATOM 2919 N LYS A 458 -72.536 15.295 -37.395 1.00 49.35 N +ATOM 2920 CA LYS A 458 -71.413 14.658 -36.710 1.00 47.85 C +ATOM 2921 C LYS A 458 -70.094 14.902 -37.435 1.00 50.29 C +ATOM 2922 O LYS A 458 -69.067 15.171 -36.797 1.00 42.79 O +ATOM 2923 CB LYS A 458 -71.682 13.155 -36.572 1.00 46.51 C +ATOM 2924 CG LYS A 458 -70.474 12.328 -36.125 1.00 51.69 C +ATOM 2925 CD LYS A 458 -70.832 10.857 -35.909 1.00 50.44 C +ATOM 2926 CE LYS A 458 -69.585 10.003 -35.721 1.00 51.91 C +ATOM 2927 NZ LYS A 458 -69.440 9.544 -34.315 1.00 61.80 N +ATOM 2928 N THR A 459 -70.091 14.780 -38.764 1.00 55.70 N +ATOM 2929 CA THR A 459 -68.851 14.957 -39.514 1.00 52.57 C +ATOM 2930 C THR A 459 -68.314 16.373 -39.365 1.00 47.69 C +ATOM 2931 O THR A 459 -67.102 16.577 -39.236 1.00 42.91 O +ATOM 2932 CB THR A 459 -69.071 14.623 -40.989 1.00 46.02 C +ATOM 2933 OG1 THR A 459 -69.633 13.311 -41.105 1.00 45.14 O +ATOM 2934 CG2 THR A 459 -67.750 14.659 -41.734 1.00 38.27 C +ATOM 2935 N LEU A 460 -69.204 17.364 -39.366 1.00 48.50 N +ATOM 2936 CA LEU A 460 -68.756 18.749 -39.284 1.00 50.78 C +ATOM 2937 C LEU A 460 -68.167 19.061 -37.914 1.00 49.29 C +ATOM 2938 O LEU A 460 -67.170 19.786 -37.811 1.00 43.40 O +ATOM 2939 CB LEU A 460 -69.924 19.681 -39.607 1.00 50.04 C +ATOM 2940 CG LEU A 460 -69.676 21.185 -39.594 1.00 43.14 C +ATOM 2941 CD1 LEU A 460 -68.456 21.521 -40.429 1.00 43.06 C +ATOM 2942 CD2 LEU A 460 -70.912 21.894 -40.131 1.00 38.00 C +ATOM 2943 N LEU A 461 -68.756 18.496 -36.855 1.00 53.52 N +ATOM 2944 CA LEU A 461 -68.273 18.753 -35.501 1.00 45.67 C +ATOM 2945 C LEU A 461 -66.880 18.169 -35.291 1.00 39.37 C +ATOM 2946 O LEU A 461 -66.018 18.814 -34.683 1.00 38.00 O +ATOM 2947 CB LEU A 461 -69.270 18.195 -34.483 1.00 38.00 C +ATOM 2948 CG LEU A 461 -70.698 18.750 -34.592 1.00 38.00 C +ATOM 2949 CD1 LEU A 461 -71.622 18.147 -33.551 1.00 38.00 C +ATOM 2950 CD2 LEU A 461 -70.709 20.263 -34.499 1.00 38.00 C +ATOM 2951 N HIS A 462 -66.634 16.957 -35.797 1.00 38.57 N +ATOM 2952 CA HIS A 462 -65.302 16.372 -35.682 1.00 40.51 C +ATOM 2953 C HIS A 462 -64.273 17.161 -36.481 1.00 40.27 C +ATOM 2954 O HIS A 462 -63.106 17.243 -36.080 1.00 38.00 O +ATOM 2955 CB HIS A 462 -65.318 14.908 -36.132 1.00 44.09 C +ATOM 2956 CG HIS A 462 -66.012 13.981 -35.180 1.00 45.92 C +ATOM 2957 ND1 HIS A 462 -65.330 13.236 -34.241 1.00 43.15 N +ATOM 2958 CD2 HIS A 462 -67.320 13.663 -35.035 1.00 46.21 C +ATOM 2959 CE1 HIS A 462 -66.191 12.511 -33.548 1.00 47.94 C +ATOM 2960 NE2 HIS A 462 -67.405 12.752 -34.010 1.00 52.04 N +ATOM 2961 N LEU A 463 -64.678 17.719 -37.622 1.00 43.63 N +ATOM 2962 CA LEU A 463 -63.763 18.520 -38.432 1.00 47.62 C +ATOM 2963 C LEU A 463 -63.435 19.845 -37.755 1.00 45.75 C +ATOM 2964 O LEU A 463 -62.271 20.267 -37.733 1.00 40.00 O +ATOM 2965 CB LEU A 463 -64.369 18.764 -39.814 1.00 46.01 C +ATOM 2966 CG LEU A 463 -64.507 17.546 -40.729 1.00 43.09 C +ATOM 2967 CD1 LEU A 463 -65.074 17.946 -42.085 1.00 43.62 C +ATOM 2968 CD2 LEU A 463 -63.163 16.854 -40.889 1.00 38.00 C +ATOM 2969 N GLN A 464 -64.453 20.521 -37.213 1.00 44.44 N +ATOM 2970 CA GLN A 464 -64.216 21.774 -36.507 1.00 43.91 C +ATOM 2971 C GLN A 464 -63.290 21.562 -35.316 1.00 45.23 C +ATOM 2972 O GLN A 464 -62.362 22.350 -35.090 1.00 41.78 O +ATOM 2973 CB GLN A 464 -65.553 22.376 -36.063 1.00 38.00 C +ATOM 2974 CG GLN A 464 -66.358 23.004 -37.193 1.00 40.90 C +ATOM 2975 CD GLN A 464 -67.731 23.481 -36.757 1.00 47.68 C +ATOM 2976 OE1 GLN A 464 -68.172 23.205 -35.644 1.00 63.23 O +ATOM 2977 NE2 GLN A 464 -68.407 24.220 -37.630 1.00 53.51 N +ATOM 2978 N LEU A 465 -63.507 20.477 -34.568 1.00 47.68 N +ATOM 2979 CA LEU A 465 -62.684 20.181 -33.400 1.00 44.26 C +ATOM 2980 C LEU A 465 -61.232 19.958 -33.795 1.00 42.39 C +ATOM 2981 O LEU A 465 -60.313 20.429 -33.114 1.00 45.57 O +ATOM 2982 CB LEU A 465 -63.241 18.949 -32.684 1.00 38.72 C +ATOM 2983 CG LEU A 465 -62.843 18.606 -31.248 1.00 38.00 C +ATOM 2984 CD1 LEU A 465 -63.853 17.638 -30.662 1.00 38.00 C +ATOM 2985 CD2 LEU A 465 -61.478 18.013 -31.182 1.00 38.80 C +ATOM 2986 N LEU A 466 -61.004 19.224 -34.879 1.00 42.01 N +ATOM 2987 CA LEU A 466 -59.648 18.936 -35.321 1.00 47.65 C +ATOM 2988 C LEU A 466 -58.939 20.155 -35.899 1.00 50.90 C +ATOM 2989 O LEU A 466 -57.766 20.044 -36.278 1.00 48.19 O +ATOM 2990 CB LEU A 466 -59.682 17.799 -36.340 1.00 44.83 C +ATOM 2991 CG LEU A 466 -59.958 16.427 -35.721 1.00 40.85 C +ATOM 2992 CD1 LEU A 466 -60.410 15.458 -36.777 1.00 42.92 C +ATOM 2993 CD2 LEU A 466 -58.705 15.903 -35.029 1.00 40.14 C +ATOM 2994 N ALA A 467 -59.601 21.310 -35.959 1.00 49.08 N +ATOM 2995 CA ALA A 467 -58.959 22.538 -36.403 1.00 47.61 C +ATOM 2996 C ALA A 467 -58.388 23.352 -35.250 1.00 50.37 C +ATOM 2997 O ALA A 467 -57.594 24.269 -35.488 1.00 52.78 O +ATOM 2998 CB ALA A 467 -59.952 23.395 -37.193 1.00 47.31 C +ATOM 2999 N GLN A 468 -58.751 23.023 -34.015 1.00 44.97 N +ATOM 3000 CA GLN A 468 -58.276 23.736 -32.840 1.00 43.06 C +ATOM 3001 C GLN A 468 -56.939 23.163 -32.397 1.00 43.44 C +ATOM 3002 O GLN A 468 -56.732 21.950 -32.438 1.00 48.74 O +ATOM 3003 CB GLN A 468 -59.305 23.619 -31.722 1.00 45.92 C +ATOM 3004 CG GLN A 468 -60.611 24.294 -32.077 1.00 48.42 C +ATOM 3005 CD GLN A 468 -61.785 23.694 -31.348 1.00 51.21 C +ATOM 3006 OE1 GLN A 468 -61.619 22.916 -30.406 1.00 47.54 O +ATOM 3007 NE2 GLN A 468 -62.987 24.055 -31.777 1.00 52.28 N +ATOM 3008 N ALA A 469 -56.037 24.046 -31.960 1.00 46.62 N +ATOM 3009 CA ALA A 469 -54.660 23.639 -31.688 1.00 46.62 C +ATOM 3010 C ALA A 469 -54.574 22.568 -30.607 1.00 48.91 C +ATOM 3011 O ALA A 469 -53.617 21.784 -30.588 1.00 47.90 O +ATOM 3012 CB ALA A 469 -53.820 24.852 -31.293 1.00 49.08 C +ATOM 3013 N ASP A 470 -55.553 22.517 -29.700 1.00 51.19 N +ATOM 3014 CA ASP A 470 -55.527 21.521 -28.631 1.00 50.82 C +ATOM 3015 C ASP A 470 -55.676 20.102 -29.169 1.00 50.29 C +ATOM 3016 O ASP A 470 -55.216 19.144 -28.535 1.00 46.04 O +ATOM 3017 CB ASP A 470 -56.635 21.818 -27.626 1.00 49.28 C +ATOM 3018 CG ASP A 470 -56.454 23.153 -26.954 1.00 55.26 C +ATOM 3019 OD1 ASP A 470 -55.436 23.328 -26.252 1.00 60.45 O +ATOM 3020 OD2 ASP A 470 -57.323 24.029 -27.138 1.00 56.96 O +ATOM 3021 N TYR A 471 -56.333 19.946 -30.312 1.00 54.13 N +ATOM 3022 CA TYR A 471 -56.484 18.656 -30.968 1.00 46.62 C +ATOM 3023 C TYR A 471 -56.359 18.835 -32.477 1.00 48.97 C +ATOM 3024 O TYR A 471 -57.238 18.441 -33.244 1.00 42.37 O +ATOM 3025 CB TYR A 471 -57.821 17.989 -30.649 1.00 44.96 C +ATOM 3026 CG TYR A 471 -58.556 18.417 -29.391 1.00 44.70 C +ATOM 3027 CD1 TYR A 471 -59.309 19.584 -29.356 1.00 49.89 C +ATOM 3028 CD2 TYR A 471 -58.562 17.607 -28.266 1.00 49.72 C +ATOM 3029 CE1 TYR A 471 -60.019 19.944 -28.222 1.00 58.55 C +ATOM 3030 CE2 TYR A 471 -59.264 17.962 -27.128 1.00 52.72 C +ATOM 3031 CZ TYR A 471 -59.989 19.130 -27.109 1.00 56.87 C +ATOM 3032 OH TYR A 471 -60.681 19.483 -25.970 1.00 57.52 O +ATOM 3033 N ARG A 472 -55.284 19.479 -32.926 1.00 49.31 N +ATOM 3034 CA ARG A 472 -55.157 19.737 -34.354 1.00 51.69 C +ATOM 3035 C ARG A 472 -54.831 18.455 -35.115 1.00 50.94 C +ATOM 3036 O ARG A 472 -54.125 17.569 -34.623 1.00 47.74 O +ATOM 3037 CB ARG A 472 -54.105 20.805 -34.630 1.00 50.73 C +ATOM 3038 CG ARG A 472 -52.697 20.444 -34.238 1.00 50.83 C +ATOM 3039 CD ARG A 472 -51.742 21.374 -34.959 1.00 52.03 C +ATOM 3040 NE ARG A 472 -52.353 22.679 -35.196 1.00 50.15 N +ATOM 3041 CZ ARG A 472 -52.200 23.734 -34.403 1.00 58.14 C +ATOM 3042 NH1 ARG A 472 -51.440 23.653 -33.317 1.00 55.67 N +ATOM 3043 NH2 ARG A 472 -52.804 24.876 -34.704 1.00 61.83 N +ATOM 3044 N LEU A 473 -55.319 18.393 -36.358 1.00 47.99 N +ATOM 3045 CA LEU A 473 -55.321 17.135 -37.098 1.00 43.00 C +ATOM 3046 C LEU A 473 -53.913 16.619 -37.352 1.00 38.00 C +ATOM 3047 O LEU A 473 -53.698 15.404 -37.373 1.00 38.00 O +ATOM 3048 CB LEU A 473 -56.069 17.310 -38.420 1.00 38.98 C +ATOM 3049 CG LEU A 473 -56.238 16.066 -39.291 1.00 38.00 C +ATOM 3050 CD1 LEU A 473 -56.926 14.967 -38.513 1.00 38.00 C +ATOM 3051 CD2 LEU A 473 -57.036 16.407 -40.529 1.00 38.00 C +ATOM 3052 N SER A 474 -52.943 17.513 -37.543 1.00 38.45 N +ATOM 3053 CA SER A 474 -51.589 17.054 -37.833 1.00 44.02 C +ATOM 3054 C SER A 474 -50.947 16.411 -36.614 1.00 41.39 C +ATOM 3055 O SER A 474 -50.201 15.435 -36.743 1.00 44.72 O +ATOM 3056 CB SER A 474 -50.717 18.205 -38.330 1.00 51.62 C +ATOM 3057 OG SER A 474 -50.652 19.254 -37.382 1.00 54.24 O +ATOM 3058 N ASP A 475 -51.181 16.972 -35.427 1.00 40.74 N +ATOM 3059 CA ASP A 475 -50.502 16.473 -34.237 1.00 43.06 C +ATOM 3060 C ASP A 475 -51.069 15.132 -33.777 1.00 41.70 C +ATOM 3061 O ASP A 475 -50.311 14.251 -33.351 1.00 38.91 O +ATOM 3062 CB ASP A 475 -50.571 17.515 -33.123 1.00 50.73 C +ATOM 3063 CG ASP A 475 -49.637 18.692 -33.368 1.00 52.39 C +ATOM 3064 OD1 ASP A 475 -48.668 18.531 -34.142 1.00 55.82 O +ATOM 3065 OD2 ASP A 475 -49.859 19.772 -32.781 1.00 51.62 O +ATOM 3066 N VAL A 476 -52.395 14.961 -33.836 1.00 41.29 N +ATOM 3067 CA VAL A 476 -53.007 13.702 -33.410 1.00 38.93 C +ATOM 3068 C VAL A 476 -52.695 12.572 -34.391 1.00 43.86 C +ATOM 3069 O VAL A 476 -52.631 11.400 -33.998 1.00 43.82 O +ATOM 3070 CB VAL A 476 -54.525 13.885 -33.222 1.00 38.00 C +ATOM 3071 CG1 VAL A 476 -54.804 14.862 -32.098 1.00 38.00 C +ATOM 3072 CG2 VAL A 476 -55.172 14.366 -34.508 1.00 39.75 C +ATOM 3073 N MET A 477 -52.507 12.896 -35.673 1.00 45.82 N +ATOM 3074 CA MET A 477 -52.058 11.903 -36.644 1.00 38.00 C +ATOM 3075 C MET A 477 -50.596 11.551 -36.419 1.00 38.00 C +ATOM 3076 O MET A 477 -50.227 10.375 -36.399 1.00 38.00 O +ATOM 3077 CB MET A 477 -52.266 12.429 -38.062 1.00 38.00 C +ATOM 3078 CG MET A 477 -53.683 12.291 -38.568 1.00 39.68 C +ATOM 3079 SD MET A 477 -54.084 10.602 -39.026 1.00 47.94 S +ATOM 3080 CE MET A 477 -52.982 10.356 -40.410 1.00 41.92 C +ATOM 3081 N ARG A 478 -49.744 12.567 -36.282 1.00 38.00 N +ATOM 3082 CA ARG A 478 -48.326 12.333 -36.035 1.00 38.00 C +ATOM 3083 C ARG A 478 -48.116 11.402 -34.854 1.00 41.98 C +ATOM 3084 O ARG A 478 -47.268 10.504 -34.902 1.00 47.19 O +ATOM 3085 CB ARG A 478 -47.619 13.663 -35.782 1.00 44.12 C +ATOM 3086 CG ARG A 478 -46.143 13.560 -35.440 1.00 40.48 C +ATOM 3087 CD ARG A 478 -45.698 14.812 -34.706 1.00 41.83 C +ATOM 3088 NE ARG A 478 -46.462 15.978 -35.147 1.00 50.19 N +ATOM 3089 CZ ARG A 478 -46.183 16.688 -36.238 1.00 51.74 C +ATOM 3090 NH1 ARG A 478 -45.153 16.348 -37.003 1.00 46.69 N +ATOM 3091 NH2 ARG A 478 -46.938 17.733 -36.569 1.00 44.67 N +ATOM 3092 N GLU A 479 -48.894 11.590 -33.786 1.00 43.06 N +ATOM 3093 CA GLU A 479 -48.723 10.760 -32.600 1.00 47.11 C +ATOM 3094 C GLU A 479 -49.270 9.353 -32.832 1.00 48.27 C +ATOM 3095 O GLU A 479 -48.582 8.361 -32.557 1.00 44.62 O +ATOM 3096 CB GLU A 479 -49.410 11.432 -31.405 1.00 49.65 C +ATOM 3097 CG GLU A 479 -49.059 10.854 -30.037 1.00 62.24 C +ATOM 3098 CD GLU A 479 -49.786 11.549 -28.886 1.00 65.75 C +ATOM 3099 OE1 GLU A 479 -50.377 12.631 -29.101 1.00 59.13 O +ATOM 3100 OE2 GLU A 479 -49.764 11.007 -27.759 1.00 71.64 O +ATOM 3101 N SER A 480 -50.471 9.247 -33.418 1.00 44.02 N +ATOM 3102 CA SER A 480 -51.086 7.943 -33.648 1.00 38.00 C +ATOM 3103 C SER A 480 -50.230 7.065 -34.544 1.00 38.12 C +ATOM 3104 O SER A 480 -50.152 5.851 -34.333 1.00 45.13 O +ATOM 3105 CB SER A 480 -52.473 8.128 -34.267 1.00 38.00 C +ATOM 3106 OG SER A 480 -53.039 6.895 -34.677 1.00 38.00 O +ATOM 3107 N LEU A 481 -49.537 7.663 -35.507 1.00 44.50 N +ATOM 3108 CA LEU A 481 -48.712 6.896 -36.426 1.00 44.71 C +ATOM 3109 C LEU A 481 -47.404 6.437 -35.799 1.00 47.87 C +ATOM 3110 O LEU A 481 -46.690 5.637 -36.413 1.00 53.52 O +ATOM 3111 CB LEU A 481 -48.432 7.733 -37.678 1.00 41.04 C +ATOM 3112 CG LEU A 481 -49.671 8.179 -38.466 1.00 38.00 C +ATOM 3113 CD1 LEU A 481 -49.326 9.283 -39.443 1.00 41.25 C +ATOM 3114 CD2 LEU A 481 -50.328 7.019 -39.194 1.00 38.00 C +ATOM 3115 N LEU A 482 -47.067 6.913 -34.601 1.00 41.52 N +ATOM 3116 CA LEU A 482 -45.831 6.469 -33.974 1.00 46.92 C +ATOM 3117 C LEU A 482 -45.923 5.046 -33.437 1.00 56.66 C +ATOM 3118 O LEU A 482 -44.883 4.394 -33.278 1.00 60.49 O +ATOM 3119 CB LEU A 482 -45.432 7.436 -32.862 1.00 48.60 C +ATOM 3120 CG LEU A 482 -44.738 8.702 -33.362 1.00 45.16 C +ATOM 3121 CD1 LEU A 482 -44.433 9.632 -32.206 1.00 49.74 C +ATOM 3122 CD2 LEU A 482 -43.471 8.338 -34.107 1.00 42.05 C +ATOM 3123 N GLU A 483 -47.139 4.538 -33.181 1.00 58.42 N +ATOM 3124 CA GLU A 483 -47.335 3.178 -32.670 1.00 56.57 C +ATOM 3125 C GLU A 483 -47.111 2.113 -33.727 1.00 52.74 C +ATOM 3126 O GLU A 483 -47.331 0.930 -33.451 1.00 46.72 O +ATOM 3127 CB GLU A 483 -48.745 3.015 -32.088 1.00 50.95 C +ATOM 3128 CG GLU A 483 -49.323 4.281 -31.462 1.00 53.97 C +ATOM 3129 CD GLU A 483 -50.788 4.134 -31.049 1.00 64.57 C +ATOM 3130 OE1 GLU A 483 -51.602 3.634 -31.863 1.00 53.93 O +ATOM 3131 OE2 GLU A 483 -51.129 4.530 -29.912 1.00 70.14 O +ATOM 3132 N ASP A 484 -46.688 2.497 -34.924 1.00 54.81 N +ATOM 3133 CA ASP A 484 -46.462 1.562 -36.012 1.00 54.80 C +ATOM 3134 C ASP A 484 -44.972 1.315 -36.204 1.00 52.40 C +ATOM 3135 O ASP A 484 -44.145 2.204 -35.989 1.00 54.85 O +ATOM 3136 CB ASP A 484 -47.078 2.073 -37.308 1.00 53.10 C +ATOM 3137 CG ASP A 484 -47.183 0.993 -38.351 1.00 55.03 C +ATOM 3138 OD1 ASP A 484 -46.863 -0.168 -38.026 1.00 56.64 O +ATOM 3139 OD2 ASP A 484 -47.573 1.298 -39.493 1.00 61.29 O +ATOM 3140 N GLN A 485 -44.641 0.084 -36.604 1.00 52.43 N +ATOM 3141 CA GLN A 485 -43.249 -0.300 -36.798 1.00 53.97 C +ATOM 3142 C GLN A 485 -42.587 0.495 -37.908 1.00 48.98 C +ATOM 3143 O GLN A 485 -41.362 0.667 -37.890 1.00 46.71 O +ATOM 3144 CB GLN A 485 -43.156 -1.801 -37.099 1.00 56.30 C +ATOM 3145 CG GLN A 485 -41.735 -2.361 -37.160 1.00 62.58 C +ATOM 3146 CD GLN A 485 -41.690 -3.873 -37.008 1.00 66.54 C +ATOM 3147 OE1 GLN A 485 -42.235 -4.426 -36.050 1.00 85.03 O +ATOM 3148 NE2 GLN A 485 -41.043 -4.549 -37.957 1.00 44.53 N +ATOM 3149 N LEU A 486 -43.370 1.018 -38.849 1.00 42.40 N +ATOM 3150 CA LEU A 486 -42.833 1.744 -39.988 1.00 45.60 C +ATOM 3151 C LEU A 486 -42.728 3.246 -39.747 1.00 52.10 C +ATOM 3152 O LEU A 486 -42.583 4.005 -40.713 1.00 55.13 O +ATOM 3153 CB LEU A 486 -43.688 1.475 -41.226 1.00 47.60 C +ATOM 3154 CG LEU A 486 -43.766 0.023 -41.695 1.00 52.07 C +ATOM 3155 CD1 LEU A 486 -44.403 -0.050 -43.077 1.00 50.42 C +ATOM 3156 CD2 LEU A 486 -42.376 -0.604 -41.703 1.00 55.34 C +ATOM 3157 N SER A 487 -42.758 3.688 -38.493 1.00 56.40 N +ATOM 3158 CA SER A 487 -42.662 5.114 -38.216 1.00 50.16 C +ATOM 3159 C SER A 487 -41.278 5.631 -38.606 1.00 44.07 C +ATOM 3160 O SER A 487 -40.266 4.985 -38.311 1.00 38.00 O +ATOM 3161 CB SER A 487 -42.932 5.398 -36.738 1.00 51.10 C +ATOM 3162 OG SER A 487 -44.273 5.097 -36.395 1.00 49.27 O +ATOM 3163 N PRO A 488 -41.197 6.807 -39.252 1.00 47.66 N +ATOM 3164 CA PRO A 488 -42.345 7.661 -39.584 1.00 49.95 C +ATOM 3165 C PRO A 488 -43.058 7.263 -40.874 1.00 43.74 C +ATOM 3166 O PRO A 488 -42.427 7.198 -41.928 1.00 40.22 O +ATOM 3167 CB PRO A 488 -41.708 9.042 -39.732 1.00 51.57 C +ATOM 3168 CG PRO A 488 -40.335 8.752 -40.239 1.00 45.51 C +ATOM 3169 CD PRO A 488 -39.919 7.424 -39.651 1.00 45.78 C +ATOM 3170 N VAL A 489 -44.367 7.009 -40.791 1.00 41.56 N +ATOM 3171 CA VAL A 489 -45.095 6.584 -41.983 1.00 43.16 C +ATOM 3172 C VAL A 489 -45.464 7.760 -42.880 1.00 42.46 C +ATOM 3173 O VAL A 489 -45.637 7.577 -44.092 1.00 42.81 O +ATOM 3174 CB VAL A 489 -46.352 5.780 -41.605 1.00 38.00 C +ATOM 3175 CG1 VAL A 489 -45.986 4.641 -40.671 1.00 45.70 C +ATOM 3176 CG2 VAL A 489 -47.395 6.664 -40.991 1.00 38.00 C +ATOM 3177 N LEU A 490 -45.570 8.966 -42.329 1.00 40.69 N +ATOM 3178 CA LEU A 490 -45.847 10.165 -43.107 1.00 38.94 C +ATOM 3179 C LEU A 490 -44.766 11.194 -42.820 1.00 45.61 C +ATOM 3180 O LEU A 490 -44.420 11.423 -41.657 1.00 39.50 O +ATOM 3181 CB LEU A 490 -47.224 10.744 -42.775 1.00 38.19 C +ATOM 3182 CG LEU A 490 -48.440 10.013 -43.338 1.00 38.00 C +ATOM 3183 CD1 LEU A 490 -49.707 10.746 -42.958 1.00 38.00 C +ATOM 3184 CD2 LEU A 490 -48.330 9.904 -44.835 1.00 38.00 C +ATOM 3185 N THR A 491 -44.227 11.797 -43.879 1.00 45.46 N +ATOM 3186 CA THR A 491 -43.264 12.874 -43.716 1.00 40.09 C +ATOM 3187 C THR A 491 -43.965 14.127 -43.199 1.00 47.15 C +ATOM 3188 O THR A 491 -45.194 14.205 -43.133 1.00 52.09 O +ATOM 3189 CB THR A 491 -42.551 13.178 -45.033 1.00 39.19 C +ATOM 3190 OG1 THR A 491 -43.455 13.838 -45.926 1.00 45.19 O +ATOM 3191 CG2 THR A 491 -42.041 11.907 -45.678 1.00 49.24 C +ATOM 3192 N GLU A 492 -43.160 15.121 -42.835 1.00 45.90 N +ATOM 3193 CA GLU A 492 -43.719 16.343 -42.266 1.00 44.34 C +ATOM 3194 C GLU A 492 -44.601 17.126 -43.235 1.00 44.92 C +ATOM 3195 O GLU A 492 -45.686 17.562 -42.811 1.00 41.08 O +ATOM 3196 CB GLU A 492 -42.580 17.211 -41.718 1.00 46.43 C +ATOM 3197 CG GLU A 492 -42.110 16.789 -40.338 1.00 53.78 C +ATOM 3198 CD GLU A 492 -43.238 16.807 -39.323 1.00 54.01 C +ATOM 3199 OE1 GLU A 492 -43.970 17.816 -39.282 1.00 55.14 O +ATOM 3200 OE2 GLU A 492 -43.384 15.830 -38.554 1.00 51.50 O +ATOM 3201 N PRO A 493 -44.234 17.334 -44.508 1.00 40.11 N +ATOM 3202 CA PRO A 493 -45.158 18.037 -45.413 1.00 38.00 C +ATOM 3203 C PRO A 493 -46.518 17.372 -45.531 1.00 40.92 C +ATOM 3204 O PRO A 493 -47.529 18.072 -45.668 1.00 41.70 O +ATOM 3205 CB PRO A 493 -44.408 18.024 -46.751 1.00 38.00 C +ATOM 3206 CG PRO A 493 -42.981 17.969 -46.370 1.00 39.53 C +ATOM 3207 CD PRO A 493 -42.926 17.102 -45.151 1.00 41.82 C +ATOM 3208 N HIS A 494 -46.575 16.040 -45.469 1.00 47.85 N +ATOM 3209 CA HIS A 494 -47.858 15.351 -45.557 1.00 50.81 C +ATOM 3210 C HIS A 494 -48.724 15.641 -44.337 1.00 47.57 C +ATOM 3211 O HIS A 494 -49.925 15.907 -44.469 1.00 45.86 O +ATOM 3212 CB HIS A 494 -47.636 13.844 -45.709 1.00 49.64 C +ATOM 3213 CG HIS A 494 -47.145 13.428 -47.063 1.00 45.94 C +ATOM 3214 ND1 HIS A 494 -45.836 13.061 -47.299 1.00 43.78 N +ATOM 3215 CD2 HIS A 494 -47.793 13.287 -48.244 1.00 38.00 C +ATOM 3216 CE1 HIS A 494 -45.695 12.730 -48.570 1.00 38.73 C +ATOM 3217 NE2 HIS A 494 -46.868 12.857 -49.164 1.00 43.56 N +ATOM 3218 N LEU A 495 -48.133 15.595 -43.141 1.00 46.64 N +ATOM 3219 CA LEU A 495 -48.904 15.812 -41.921 1.00 48.56 C +ATOM 3220 C LEU A 495 -49.475 17.223 -41.874 1.00 50.72 C +ATOM 3221 O LEU A 495 -50.670 17.413 -41.617 1.00 49.28 O +ATOM 3222 CB LEU A 495 -48.023 15.553 -40.700 1.00 50.42 C +ATOM 3223 CG LEU A 495 -47.575 14.106 -40.513 1.00 51.24 C +ATOM 3224 CD1 LEU A 495 -46.478 14.015 -39.460 1.00 46.93 C +ATOM 3225 CD2 LEU A 495 -48.772 13.232 -40.147 1.00 48.39 C +ATOM 3226 N LEU A 496 -48.636 18.229 -42.140 1.00 45.61 N +ATOM 3227 CA LEU A 496 -49.114 19.607 -42.125 1.00 42.56 C +ATOM 3228 C LEU A 496 -50.142 19.855 -43.221 1.00 43.04 C +ATOM 3229 O LEU A 496 -51.042 20.686 -43.049 1.00 38.78 O +ATOM 3230 CB LEU A 496 -47.931 20.566 -42.263 1.00 38.00 C +ATOM 3231 CG LEU A 496 -46.991 20.658 -41.059 1.00 38.00 C +ATOM 3232 CD1 LEU A 496 -46.111 21.884 -41.165 1.00 48.98 C +ATOM 3233 CD2 LEU A 496 -47.788 20.704 -39.767 1.00 38.69 C +ATOM 3234 N ALA A 497 -50.058 19.101 -44.322 1.00 41.02 N +ATOM 3235 CA ALA A 497 -51.010 19.258 -45.415 1.00 42.30 C +ATOM 3236 C ALA A 497 -52.423 18.931 -44.969 1.00 46.95 C +ATOM 3237 O ALA A 497 -53.388 19.499 -45.491 1.00 45.34 O +ATOM 3238 CB ALA A 497 -50.608 18.371 -46.592 1.00 45.53 C +ATOM 3239 N LEU A 498 -52.563 18.009 -44.018 1.00 48.39 N +ATOM 3240 CA LEU A 498 -53.883 17.686 -43.496 1.00 46.86 C +ATOM 3241 C LEU A 498 -54.547 18.918 -42.905 1.00 50.91 C +ATOM 3242 O LEU A 498 -55.736 19.165 -43.142 1.00 48.07 O +ATOM 3243 CB LEU A 498 -53.757 16.599 -42.437 1.00 42.06 C +ATOM 3244 CG LEU A 498 -53.142 15.314 -42.961 1.00 40.04 C +ATOM 3245 CD1 LEU A 498 -52.886 14.368 -41.815 1.00 43.33 C +ATOM 3246 CD2 LEU A 498 -54.098 14.715 -43.968 1.00 42.44 C +ATOM 3247 N ASP A 499 -53.777 19.731 -42.174 1.00 48.65 N +ATOM 3248 CA ASP A 499 -54.331 20.937 -41.573 1.00 47.30 C +ATOM 3249 C ASP A 499 -54.861 21.879 -42.641 1.00 50.84 C +ATOM 3250 O ASP A 499 -56.015 22.319 -42.580 1.00 49.26 O +ATOM 3251 CB ASP A 499 -53.269 21.637 -40.726 1.00 44.89 C +ATOM 3252 CG ASP A 499 -52.964 20.898 -39.441 1.00 48.63 C +ATOM 3253 OD1 ASP A 499 -53.848 20.171 -38.943 1.00 49.44 O +ATOM 3254 OD2 ASP A 499 -51.839 21.059 -38.924 1.00 49.77 O +ATOM 3255 N ARG A 500 -54.033 22.173 -43.648 1.00 52.74 N +ATOM 3256 CA ARG A 500 -54.440 23.084 -44.713 1.00 51.82 C +ATOM 3257 C ARG A 500 -55.641 22.541 -45.475 1.00 50.29 C +ATOM 3258 O ARG A 500 -56.581 23.286 -45.784 1.00 45.37 O +ATOM 3259 CB ARG A 500 -53.267 23.324 -45.659 1.00 46.03 C +ATOM 3260 CG ARG A 500 -53.656 23.992 -46.954 1.00 47.96 C +ATOM 3261 CD ARG A 500 -52.501 23.976 -47.922 1.00 49.17 C +ATOM 3262 NE ARG A 500 -51.847 22.672 -47.948 1.00 51.77 N +ATOM 3263 CZ ARG A 500 -51.019 22.275 -48.908 1.00 56.08 C +ATOM 3264 NH1 ARG A 500 -50.753 23.081 -49.926 1.00 73.29 N +ATOM 3265 NH2 ARG A 500 -50.463 21.072 -48.855 1.00 53.43 N +ATOM 3266 N ARG A 501 -55.620 21.243 -45.798 1.00 51.32 N +ATOM 3267 CA ARG A 501 -56.760 20.632 -46.470 1.00 51.62 C +ATOM 3268 C ARG A 501 -57.991 20.624 -45.578 1.00 47.26 C +ATOM 3269 O ARG A 501 -59.117 20.638 -46.084 1.00 40.55 O +ATOM 3270 CB ARG A 501 -56.418 19.211 -46.923 1.00 49.92 C +ATOM 3271 CG ARG A 501 -55.239 19.137 -47.894 1.00 52.12 C +ATOM 3272 CD ARG A 501 -55.185 17.800 -48.626 1.00 52.12 C +ATOM 3273 NE ARG A 501 -53.975 17.650 -49.431 1.00 49.55 N +ATOM 3274 CZ ARG A 501 -53.000 16.789 -49.166 1.00 47.36 C +ATOM 3275 NH1 ARG A 501 -53.099 15.981 -48.121 1.00 48.76 N +ATOM 3276 NH2 ARG A 501 -51.936 16.722 -49.957 1.00 44.24 N +ATOM 3277 N LEU A 502 -57.796 20.599 -44.256 1.00 47.94 N +ATOM 3278 CA LEU A 502 -58.926 20.692 -43.337 1.00 46.68 C +ATOM 3279 C LEU A 502 -59.576 22.067 -43.399 1.00 47.10 C +ATOM 3280 O LEU A 502 -60.808 22.180 -43.393 1.00 43.14 O +ATOM 3281 CB LEU A 502 -58.467 20.373 -41.915 1.00 42.26 C +ATOM 3282 CG LEU A 502 -59.516 20.493 -40.811 1.00 46.11 C +ATOM 3283 CD1 LEU A 502 -60.592 19.435 -40.964 1.00 38.92 C +ATOM 3284 CD2 LEU A 502 -58.836 20.377 -39.460 1.00 47.64 C +ATOM 3285 N GLN A 503 -58.764 23.124 -43.473 1.00 47.52 N +ATOM 3286 CA GLN A 503 -59.315 24.465 -43.606 1.00 42.05 C +ATOM 3287 C GLN A 503 -60.148 24.577 -44.871 1.00 41.07 C +ATOM 3288 O GLN A 503 -61.261 25.114 -44.847 1.00 39.15 O +ATOM 3289 CB GLN A 503 -58.182 25.489 -43.615 1.00 39.14 C +ATOM 3290 CG GLN A 503 -57.462 25.616 -42.286 1.00 46.96 C +ATOM 3291 CD GLN A 503 -58.348 26.168 -41.185 1.00 51.66 C +ATOM 3292 OE1 GLN A 503 -59.024 27.180 -41.365 1.00 63.37 O +ATOM 3293 NE2 GLN A 503 -58.345 25.504 -40.033 1.00 45.05 N +ATOM 3294 N THR A 504 -59.640 24.029 -45.976 1.00 40.11 N +ATOM 3295 CA THR A 504 -60.355 24.093 -47.245 1.00 42.00 C +ATOM 3296 C THR A 504 -61.715 23.414 -47.152 1.00 43.13 C +ATOM 3297 O THR A 504 -62.681 23.853 -47.787 1.00 40.91 O +ATOM 3298 CB THR A 504 -59.505 23.458 -48.342 1.00 44.80 C +ATOM 3299 OG1 THR A 504 -58.239 24.127 -48.398 1.00 40.33 O +ATOM 3300 CG2 THR A 504 -60.203 23.570 -49.691 1.00 42.61 C +ATOM 3301 N ILE A 505 -61.812 22.342 -46.367 1.00 46.07 N +ATOM 3302 CA ILE A 505 -63.102 21.689 -46.170 1.00 45.58 C +ATOM 3303 C ILE A 505 -64.022 22.585 -45.357 1.00 47.70 C +ATOM 3304 O ILE A 505 -65.195 22.780 -45.701 1.00 45.40 O +ATOM 3305 CB ILE A 505 -62.916 20.324 -45.490 1.00 38.32 C +ATOM 3306 CG1 ILE A 505 -61.942 19.465 -46.280 1.00 40.15 C +ATOM 3307 CG2 ILE A 505 -64.247 19.613 -45.378 1.00 38.72 C +ATOM 3308 CD1 ILE A 505 -61.517 18.242 -45.537 1.00 43.74 C +ATOM 3309 N LEU A 506 -63.498 23.146 -44.266 1.00 46.67 N +ATOM 3310 CA LEU A 506 -64.299 24.028 -43.428 1.00 45.22 C +ATOM 3311 C LEU A 506 -64.685 25.288 -44.182 1.00 52.00 C +ATOM 3312 O LEU A 506 -65.841 25.722 -44.126 1.00 52.45 O +ATOM 3313 CB LEU A 506 -63.524 24.377 -42.162 1.00 44.37 C +ATOM 3314 CG LEU A 506 -63.307 23.193 -41.227 1.00 43.46 C +ATOM 3315 CD1 LEU A 506 -62.365 23.568 -40.102 1.00 41.74 C +ATOM 3316 CD2 LEU A 506 -64.656 22.745 -40.685 1.00 41.17 C +ATOM 3317 N ARG A 507 -63.740 25.859 -44.932 1.00 53.66 N +ATOM 3318 CA ARG A 507 -64.047 27.047 -45.715 1.00 48.17 C +ATOM 3319 C ARG A 507 -65.147 26.777 -46.730 1.00 46.18 C +ATOM 3320 O ARG A 507 -66.020 27.628 -46.931 1.00 44.56 O +ATOM 3321 CB ARG A 507 -62.778 27.543 -46.405 1.00 38.00 C +ATOM 3322 CG ARG A 507 -63.007 28.714 -47.313 1.00 44.74 C +ATOM 3323 CD ARG A 507 -61.710 29.399 -47.713 1.00 61.99 C +ATOM 3324 NE ARG A 507 -60.672 28.480 -48.178 1.00 58.83 N +ATOM 3325 CZ ARG A 507 -59.611 28.130 -47.458 1.00 51.63 C +ATOM 3326 NH1 ARG A 507 -59.450 28.621 -46.235 1.00 45.00 N +ATOM 3327 NH2 ARG A 507 -58.709 27.294 -47.959 1.00 47.26 N +ATOM 3328 N THR A 508 -65.175 25.576 -47.313 1.00 45.05 N +ATOM 3329 CA THR A 508 -66.235 25.253 -48.262 1.00 47.47 C +ATOM 3330 C THR A 508 -67.579 25.127 -47.557 1.00 53.32 C +ATOM 3331 O THR A 508 -68.611 25.529 -48.107 1.00 60.11 O +ATOM 3332 CB THR A 508 -65.912 23.965 -49.028 1.00 41.44 C +ATOM 3333 OG1 THR A 508 -64.663 24.100 -49.713 1.00 38.00 O +ATOM 3334 CG2 THR A 508 -66.993 23.682 -50.055 1.00 43.50 C +ATOM 3335 N VAL A 509 -67.594 24.563 -46.346 1.00 46.91 N +ATOM 3336 CA VAL A 509 -68.853 24.424 -45.613 1.00 54.36 C +ATOM 3337 C VAL A 509 -69.429 25.795 -45.285 1.00 64.86 C +ATOM 3338 O VAL A 509 -70.565 26.118 -45.655 1.00 64.10 O +ATOM 3339 CB VAL A 509 -68.652 23.582 -44.343 1.00 44.52 C +ATOM 3340 CG1 VAL A 509 -69.954 23.509 -43.552 1.00 38.00 C +ATOM 3341 CG2 VAL A 509 -68.169 22.201 -44.708 1.00 45.36 C +ATOM 3342 N GLU A 510 -68.644 26.630 -44.597 1.00 69.56 N +ATOM 3343 CA GLU A 510 -69.110 27.975 -44.280 1.00 67.43 C +ATOM 3344 C GLU A 510 -69.261 28.806 -45.541 1.00 63.32 C +ATOM 3345 O GLU A 510 -70.110 29.702 -45.593 1.00 62.32 O +ATOM 3346 CB GLU A 510 -68.157 28.651 -43.286 1.00 68.08 C +ATOM 3347 CG GLU A 510 -66.903 29.288 -43.897 1.00 69.12 C +ATOM 3348 CD GLU A 510 -66.014 29.958 -42.851 1.00 77.48 C +ATOM 3349 OE1 GLU A 510 -66.551 30.399 -41.812 1.00 78.13 O +ATOM 3350 OE2 GLU A 510 -64.782 30.044 -43.067 1.00 67.67 O +ATOM 3351 N GLY A 511 -68.495 28.484 -46.583 1.00 59.86 N +ATOM 3352 CA GLY A 511 -68.584 29.257 -47.807 1.00 70.51 C +ATOM 3353 C GLY A 511 -69.928 29.090 -48.487 1.00 78.81 C +ATOM 3354 O GLY A 511 -70.586 30.073 -48.831 1.00 86.91 O +ATOM 3355 N CYS A 512 -70.365 27.846 -48.669 1.00 74.95 N +ATOM 3356 CA CYS A 512 -71.648 27.588 -49.306 1.00 78.00 C +ATOM 3357 C CYS A 512 -72.809 27.577 -48.314 1.00 67.90 C +ATOM 3358 O CYS A 512 -73.956 27.369 -48.726 1.00 69.17 O +ATOM 3359 CB CYS A 512 -71.580 26.284 -50.116 1.00 83.17 C +ATOM 3360 SG CYS A 512 -71.857 24.755 -49.221 1.00 80.23 S +ATOM 3361 N ILE A 513 -72.544 27.823 -47.028 1.00 65.21 N +ATOM 3362 CA ILE A 513 -73.629 28.106 -46.090 1.00 69.75 C +ATOM 3363 C ILE A 513 -74.290 29.437 -46.431 1.00 67.31 C +ATOM 3364 O ILE A 513 -75.509 29.595 -46.302 1.00 58.86 O +ATOM 3365 CB ILE A 513 -73.106 28.092 -44.640 1.00 64.73 C +ATOM 3366 CG1 ILE A 513 -73.278 26.708 -44.018 1.00 68.11 C +ATOM 3367 CG2 ILE A 513 -73.825 29.127 -43.789 1.00 66.02 C +ATOM 3368 CD1 ILE A 513 -73.034 26.687 -42.534 1.00 53.52 C +ATOM 3369 N VAL A 514 -73.497 30.408 -46.893 1.00 65.63 N +ATOM 3370 CA VAL A 514 -74.014 31.729 -47.229 1.00 56.01 C +ATOM 3371 C VAL A 514 -75.023 31.663 -48.362 1.00 62.79 C +ATOM 3372 O VAL A 514 -75.884 32.546 -48.482 1.00 67.73 O +ATOM 3373 CB VAL A 514 -72.865 32.679 -47.611 1.00 47.95 C +ATOM 3374 CG1 VAL A 514 -71.694 32.533 -46.661 1.00 47.54 C +ATOM 3375 CG2 VAL A 514 -72.426 32.467 -49.064 1.00 52.58 C +ATOM 3376 N ALA A 515 -74.964 30.616 -49.181 1.00 64.31 N +ATOM 3377 CA ALA A 515 -75.849 30.461 -50.328 1.00 62.92 C +ATOM 3378 C ALA A 515 -77.064 29.593 -50.035 1.00 69.44 C +ATOM 3379 O ALA A 515 -77.999 29.578 -50.840 1.00 78.15 O +ATOM 3380 CB ALA A 515 -75.069 29.880 -51.512 1.00 54.90 C +ATOM 3381 N HIS A 516 -77.061 28.844 -48.931 1.00 65.25 N +ATOM 3382 CA HIS A 516 -78.189 27.983 -48.600 1.00 67.27 C +ATOM 3383 C HIS A 516 -78.629 28.049 -47.140 1.00 76.50 C +ATOM 3384 O HIS A 516 -79.726 27.563 -46.831 1.00 71.57 O +ATOM 3385 CB HIS A 516 -77.873 26.521 -48.952 1.00 69.17 C +ATOM 3386 CG HIS A 516 -77.457 26.310 -50.376 1.00 70.76 C +ATOM 3387 ND1 HIS A 516 -76.255 26.764 -50.876 1.00 73.24 N +ATOM 3388 CD2 HIS A 516 -78.075 25.678 -51.402 1.00 73.95 C +ATOM 3389 CE1 HIS A 516 -76.151 26.425 -52.148 1.00 70.00 C +ATOM 3390 NE2 HIS A 516 -77.243 25.766 -52.493 1.00 75.66 N +ATOM 3391 N GLY A 517 -77.828 28.612 -46.240 1.00 77.43 N +ATOM 3392 CA GLY A 517 -78.151 28.654 -44.827 1.00 75.86 C +ATOM 3393 C GLY A 517 -77.932 27.315 -44.140 1.00 76.87 C +ATOM 3394 O GLY A 517 -77.791 26.270 -44.770 1.00 78.60 O +ATOM 3395 N GLN A 518 -77.908 27.356 -42.806 1.00 72.30 N +ATOM 3396 CA GLN A 518 -77.724 26.137 -42.020 1.00 66.97 C +ATOM 3397 C GLN A 518 -78.903 25.166 -42.127 1.00 71.13 C +ATOM 3398 O GLN A 518 -78.827 24.064 -41.569 1.00 66.28 O +ATOM 3399 CB GLN A 518 -77.469 26.502 -40.557 1.00 64.91 C +ATOM 3400 CG GLN A 518 -76.153 27.242 -40.313 1.00 63.15 C +ATOM 3401 CD GLN A 518 -75.818 27.364 -38.832 1.00 67.23 C +ATOM 3402 OE1 GLN A 518 -76.424 26.698 -37.991 1.00 71.00 O +ATOM 3403 NE2 GLN A 518 -74.851 28.220 -38.508 1.00 54.77 N +ATOM 3404 N GLN A 519 -79.972 25.540 -42.835 1.00 78.19 N +ATOM 3405 CA GLN A 519 -81.095 24.631 -43.050 1.00 77.20 C +ATOM 3406 C GLN A 519 -80.680 23.443 -43.911 1.00 78.81 C +ATOM 3407 O GLN A 519 -80.860 22.285 -43.518 1.00 76.22 O +ATOM 3408 CB GLN A 519 -82.262 25.387 -43.696 1.00 87.99 C +ATOM 3409 CG GLN A 519 -83.305 24.497 -44.384 1.00 99.70 C +ATOM 3410 CD GLN A 519 -83.631 24.947 -45.808 1.00 98.98 C +ATOM 3411 OE1 GLN A 519 -82.741 25.065 -46.658 1.00 96.93 O +ATOM 3412 NE2 GLN A 519 -84.912 25.196 -46.072 1.00 90.38 N +ATOM 3413 N SER A 520 -80.118 23.716 -45.089 1.00 75.63 N +ATOM 3414 CA SER A 520 -79.823 22.695 -46.082 1.00 69.39 C +ATOM 3415 C SER A 520 -78.347 22.329 -46.154 1.00 70.36 C +ATOM 3416 O SER A 520 -77.967 21.534 -47.018 1.00 78.60 O +ATOM 3417 CB SER A 520 -80.298 23.159 -47.465 1.00 69.89 C +ATOM 3418 OG SER A 520 -79.992 22.206 -48.468 1.00 77.00 O +ATOM 3419 N VAL A 521 -77.502 22.879 -45.284 1.00 57.82 N +ATOM 3420 CA VAL A 521 -76.091 22.514 -45.267 1.00 56.19 C +ATOM 3421 C VAL A 521 -75.707 21.729 -44.020 1.00 61.38 C +ATOM 3422 O VAL A 521 -74.589 21.195 -43.956 1.00 64.35 O +ATOM 3423 CB VAL A 521 -75.195 23.756 -45.433 1.00 54.21 C +ATOM 3424 CG1 VAL A 521 -73.806 23.368 -45.909 1.00 54.69 C +ATOM 3425 CG2 VAL A 521 -75.809 24.710 -46.433 1.00 56.63 C +ATOM 3426 N ILE A 522 -76.618 21.573 -43.060 1.00 67.30 N +ATOM 3427 CA ILE A 522 -76.377 20.768 -41.865 1.00 60.48 C +ATOM 3428 C ILE A 522 -77.567 19.839 -41.678 1.00 66.36 C +ATOM 3429 O ILE A 522 -78.707 20.301 -41.529 1.00 68.19 O +ATOM 3430 CB ILE A 522 -76.157 21.632 -40.611 1.00 46.27 C +ATOM 3431 CG1 ILE A 522 -74.680 21.984 -40.456 1.00 38.00 C +ATOM 3432 CG2 ILE A 522 -76.641 20.922 -39.366 1.00 56.16 C +ATOM 3433 CD1 ILE A 522 -74.258 23.172 -41.253 1.00 41.30 C +ATOM 3434 N VAL A 523 -77.298 18.541 -41.653 1.00 64.07 N +ATOM 3435 CA VAL A 523 -78.331 17.511 -41.580 1.00 66.57 C +ATOM 3436 C VAL A 523 -78.110 16.761 -40.273 1.00 69.20 C +ATOM 3437 O VAL A 523 -77.370 15.775 -40.207 1.00 64.28 O +ATOM 3438 CB VAL A 523 -78.297 16.570 -42.785 1.00 71.04 C +ATOM 3439 CG1 VAL A 523 -79.213 17.081 -43.889 1.00 65.26 C +ATOM 3440 CG2 VAL A 523 -76.876 16.454 -43.301 1.00 67.46 C +ATOM 3441 N ASP A 524 -78.735 17.253 -39.207 1.00 78.80 N +ATOM 3442 CA ASP A 524 -78.574 16.674 -37.879 1.00 84.44 C +ATOM 3443 C ASP A 524 -79.494 15.476 -37.669 1.00 90.68 C +ATOM 3444 O ASP A 524 -80.162 15.381 -36.636 1.00 99.67 O +ATOM 3445 CB ASP A 524 -78.826 17.741 -36.812 1.00 80.89 C +ATOM 3446 CG ASP A 524 -80.144 18.469 -37.016 1.00 99.45 C +ATOM 3447 OD1 ASP A 524 -80.579 18.603 -38.181 1.00 94.96 O +ATOM 3448 OD2 ASP A 524 -80.744 18.906 -36.008 1.00110.04 O +ATOM 3449 N GLY A 525 -79.544 14.563 -38.639 1.00 81.03 N +ATOM 3450 CA GLY A 525 -80.300 13.343 -38.482 1.00 83.46 C +ATOM 3451 C GLY A 525 -79.760 12.498 -37.344 1.00 96.62 C +ATOM 3452 O GLY A 525 -78.587 12.605 -36.967 1.00103.85 O +ATOM 3453 N PRO A 526 -80.608 11.627 -36.773 1.00104.91 N +ATOM 3454 CA PRO A 526 -80.200 10.824 -35.611 1.00104.35 C +ATOM 3455 C PRO A 526 -79.246 9.682 -35.969 1.00105.24 C +ATOM 3456 O PRO A 526 -78.917 9.497 -37.144 1.00101.73 O +ATOM 3457 CB PRO A 526 -81.530 10.279 -35.080 1.00 91.92 C +ATOM 3458 CG PRO A 526 -82.412 10.222 -36.281 1.00 91.45 C +ATOM 3459 CD PRO A 526 -82.010 11.380 -37.158 1.00 93.39 C +TER 3460 PRO A 526 +ATOM 3461 N SER C 134 -5.555 22.103 -75.953 1.00 70.85 N +ATOM 3462 CA SER C 134 -4.121 21.850 -75.885 1.00 74.77 C +ATOM 3463 C SER C 134 -3.849 20.353 -75.765 1.00 85.14 C +ATOM 3464 O SER C 134 -3.062 19.796 -76.530 1.00 79.35 O +ATOM 3465 CB SER C 134 -3.492 22.603 -74.707 1.00 76.97 C +ATOM 3466 OG SER C 134 -3.908 22.055 -73.466 1.00 78.94 O +ATOM 3467 N VAL C 135 -4.510 19.712 -74.797 1.00 88.32 N +ATOM 3468 CA VAL C 135 -4.308 18.282 -74.566 1.00 85.66 C +ATOM 3469 C VAL C 135 -4.707 17.486 -75.801 1.00 86.60 C +ATOM 3470 O VAL C 135 -3.946 16.645 -76.296 1.00 78.30 O +ATOM 3471 CB VAL C 135 -5.098 17.823 -73.327 1.00 80.98 C +ATOM 3472 CG1 VAL C 135 -4.535 16.515 -72.797 1.00 77.06 C +ATOM 3473 CG2 VAL C 135 -5.082 18.902 -72.257 1.00 83.50 C +ATOM 3474 N LEU C 136 -5.911 17.750 -76.317 1.00 83.95 N +ATOM 3475 CA LEU C 136 -6.370 17.079 -77.527 1.00 79.86 C +ATOM 3476 C LEU C 136 -5.490 17.441 -78.714 1.00 79.96 C +ATOM 3477 O LEU C 136 -5.167 16.583 -79.546 1.00 73.03 O +ATOM 3478 CB LEU C 136 -7.826 17.452 -77.797 1.00 81.46 C +ATOM 3479 CG LEU C 136 -8.611 16.496 -78.690 1.00 81.39 C +ATOM 3480 CD1 LEU C 136 -8.386 15.069 -78.231 1.00 72.54 C +ATOM 3481 CD2 LEU C 136 -10.096 16.844 -78.686 1.00 81.76 C +ATOM 3482 N GLN C 137 -5.102 18.713 -78.812 1.00 78.74 N +ATOM 3483 CA GLN C 137 -4.166 19.129 -79.848 1.00 81.85 C +ATOM 3484 C GLN C 137 -2.866 18.340 -79.753 1.00 85.22 C +ATOM 3485 O GLN C 137 -2.304 17.927 -80.775 1.00 78.93 O +ATOM 3486 CB GLN C 137 -3.905 20.630 -79.731 1.00 82.87 C +ATOM 3487 CG GLN C 137 -3.109 21.219 -80.878 1.00 92.59 C +ATOM 3488 CD GLN C 137 -3.846 21.123 -82.198 1.00 98.20 C +ATOM 3489 OE1 GLN C 137 -5.052 21.367 -82.264 1.00100.61 O +ATOM 3490 NE2 GLN C 137 -3.122 20.783 -83.261 1.00 86.75 N +ATOM 3491 N SER C 138 -2.378 18.113 -78.528 1.00 90.62 N +ATOM 3492 CA SER C 138 -1.123 17.387 -78.341 1.00 88.57 C +ATOM 3493 C SER C 138 -1.299 15.896 -78.588 1.00 84.29 C +ATOM 3494 O SER C 138 -0.384 15.237 -79.096 1.00 76.24 O +ATOM 3495 CB SER C 138 -0.579 17.612 -76.930 1.00 84.47 C +ATOM 3496 OG SER C 138 -0.424 18.989 -76.644 1.00100.09 O +ATOM 3497 N LEU C 139 -2.460 15.345 -78.217 1.00 83.51 N +ATOM 3498 CA LEU C 139 -2.689 13.915 -78.395 1.00 83.46 C +ATOM 3499 C LEU C 139 -2.560 13.523 -79.859 1.00 77.50 C +ATOM 3500 O LEU C 139 -1.792 12.620 -80.208 1.00 69.53 O +ATOM 3501 CB LEU C 139 -4.068 13.521 -77.866 1.00 87.74 C +ATOM 3502 CG LEU C 139 -4.373 12.036 -78.116 1.00 86.53 C +ATOM 3503 CD1 LEU C 139 -3.550 11.141 -77.187 1.00 77.56 C +ATOM 3504 CD2 LEU C 139 -5.868 11.716 -78.026 1.00 79.08 C +ATOM 3505 N PHE C 140 -3.298 14.207 -80.735 1.00 77.84 N +ATOM 3506 CA PHE C 140 -3.184 13.933 -82.159 1.00 74.98 C +ATOM 3507 C PHE C 140 -1.818 14.331 -82.701 1.00 75.13 C +ATOM 3508 O PHE C 140 -1.436 13.868 -83.783 1.00 74.85 O +ATOM 3509 CB PHE C 140 -4.297 14.651 -82.923 1.00 70.10 C +ATOM 3510 CG PHE C 140 -5.686 14.193 -82.553 1.00 72.99 C +ATOM 3511 CD1 PHE C 140 -5.901 12.916 -82.057 1.00 66.88 C +ATOM 3512 CD2 PHE C 140 -6.781 15.027 -82.734 1.00 81.11 C +ATOM 3513 CE1 PHE C 140 -7.175 12.489 -81.726 1.00 63.54 C +ATOM 3514 CE2 PHE C 140 -8.063 14.601 -82.409 1.00 70.41 C +ATOM 3515 CZ PHE C 140 -8.258 13.331 -81.905 1.00 62.92 C +ATOM 3516 N GLU C 141 -1.067 15.152 -81.961 1.00 78.09 N +ATOM 3517 CA GLU C 141 0.297 15.501 -82.332 1.00 81.27 C +ATOM 3518 C GLU C 141 1.306 14.447 -81.899 1.00 77.28 C +ATOM 3519 O GLU C 141 2.479 14.542 -82.277 1.00 81.06 O +ATOM 3520 CB GLU C 141 0.676 16.859 -81.727 1.00 86.17 C +ATOM 3521 CG GLU C 141 0.518 18.034 -82.696 1.00 95.55 C +ATOM 3522 CD GLU C 141 0.679 19.391 -82.019 1.00 91.71 C +ATOM 3523 OE1 GLU C 141 1.833 19.792 -81.753 1.00 94.55 O +ATOM 3524 OE2 GLU C 141 -0.344 20.059 -81.752 1.00 81.55 O +ATOM 3525 N HIS C 142 0.877 13.444 -81.128 1.00 71.75 N +ATOM 3526 CA HIS C 142 1.757 12.361 -80.722 1.00 72.48 C +ATOM 3527 C HIS C 142 2.204 11.564 -81.947 1.00 76.35 C +ATOM 3528 O HIS C 142 1.544 11.592 -82.986 1.00 78.37 O +ATOM 3529 CB HIS C 142 1.029 11.440 -79.746 1.00 73.11 C +ATOM 3530 CG HIS C 142 1.935 10.700 -78.816 1.00 73.29 C +ATOM 3531 ND1 HIS C 142 2.582 11.310 -77.764 1.00 81.94 N +ATOM 3532 CD2 HIS C 142 2.327 9.405 -78.802 1.00 67.29 C +ATOM 3533 CE1 HIS C 142 3.318 10.415 -77.127 1.00 87.70 C +ATOM 3534 NE2 HIS C 142 3.181 9.251 -77.738 1.00 72.72 N +ATOM 3535 N PRO C 143 3.322 10.836 -81.850 1.00 78.08 N +ATOM 3536 CA PRO C 143 3.702 9.912 -82.929 1.00 79.13 C +ATOM 3537 C PRO C 143 2.972 8.578 -82.900 1.00 72.64 C +ATOM 3538 O PRO C 143 3.154 7.769 -83.819 1.00 64.05 O +ATOM 3539 CB PRO C 143 5.207 9.711 -82.694 1.00 77.88 C +ATOM 3540 CG PRO C 143 5.396 9.956 -81.238 1.00 77.21 C +ATOM 3541 CD PRO C 143 4.421 11.043 -80.888 1.00 77.52 C +ATOM 3542 N LEU C 144 2.135 8.334 -81.897 1.00 73.20 N +ATOM 3543 CA LEU C 144 1.331 7.121 -81.825 1.00 72.51 C +ATOM 3544 C LEU C 144 -0.039 7.294 -82.460 1.00 74.48 C +ATOM 3545 O LEU C 144 -0.849 6.361 -82.429 1.00 73.81 O +ATOM 3546 CB LEU C 144 1.162 6.678 -80.367 1.00 70.81 C +ATOM 3547 CG LEU C 144 1.701 5.306 -79.955 1.00 63.14 C +ATOM 3548 CD1 LEU C 144 0.625 4.538 -79.216 1.00 60.96 C +ATOM 3549 CD2 LEU C 144 2.208 4.511 -81.149 1.00 62.07 C +ATOM 3550 N TYR C 145 -0.321 8.472 -83.009 1.00 74.90 N +ATOM 3551 CA TYR C 145 -1.601 8.756 -83.640 1.00 74.20 C +ATOM 3552 C TYR C 145 -1.456 9.139 -85.106 1.00 78.71 C +ATOM 3553 O TYR C 145 -2.450 9.522 -85.732 1.00 81.29 O +ATOM 3554 CB TYR C 145 -2.344 9.863 -82.883 1.00 69.23 C +ATOM 3555 CG TYR C 145 -3.095 9.392 -81.658 1.00 70.86 C +ATOM 3556 CD1 TYR C 145 -2.459 8.690 -80.638 1.00 66.41 C +ATOM 3557 CD2 TYR C 145 -4.456 9.642 -81.530 1.00 73.50 C +ATOM 3558 CE1 TYR C 145 -3.163 8.258 -79.522 1.00 63.87 C +ATOM 3559 CE2 TYR C 145 -5.165 9.216 -80.423 1.00 67.56 C +ATOM 3560 CZ TYR C 145 -4.517 8.526 -79.424 1.00 65.14 C +ATOM 3561 OH TYR C 145 -5.240 8.109 -78.331 1.00 61.75 O +ATOM 3562 N ARG C 146 -0.252 9.058 -85.670 1.00 74.41 N +ATOM 3563 CA ARG C 146 -0.038 9.405 -87.067 1.00 79.50 C +ATOM 3564 C ARG C 146 0.244 8.193 -87.945 1.00 85.63 C +ATOM 3565 O ARG C 146 0.470 8.356 -89.149 1.00 86.80 O +ATOM 3566 CB ARG C 146 1.103 10.425 -87.183 1.00 86.64 C +ATOM 3567 CG ARG C 146 1.233 11.304 -85.948 1.00 80.81 C +ATOM 3568 CD ARG C 146 2.013 12.598 -86.170 1.00 84.86 C +ATOM 3569 NE ARG C 146 1.171 13.638 -86.763 1.00102.06 N +ATOM 3570 CZ ARG C 146 1.432 14.942 -86.713 1.00 97.45 C +ATOM 3571 NH1 ARG C 146 2.515 15.383 -86.086 1.00 94.45 N +ATOM 3572 NH2 ARG C 146 0.601 15.810 -87.282 1.00 81.18 N +ATOM 3573 N THR C 147 0.217 6.985 -87.379 1.00 85.55 N +ATOM 3574 CA THR C 147 0.399 5.749 -88.134 1.00 84.23 C +ATOM 3575 C THR C 147 -0.651 5.588 -89.228 1.00 82.28 C +ATOM 3576 O THR C 147 -1.805 5.263 -88.938 1.00 84.39 O +ATOM 3577 CB THR C 147 0.340 4.544 -87.198 1.00 78.33 C +ATOM 3578 OG1 THR C 147 1.307 4.706 -86.154 1.00 88.46 O +ATOM 3579 CG2 THR C 147 0.640 3.266 -87.974 1.00 67.39 C +ATOM 3580 N VAL C 148 -0.262 5.799 -90.486 1.00 85.59 N +ATOM 3581 CA VAL C 148 -1.206 5.672 -91.591 1.00 87.37 C +ATOM 3582 C VAL C 148 -1.556 4.205 -91.827 1.00 82.44 C +ATOM 3583 O VAL C 148 -0.799 3.292 -91.470 1.00 84.27 O +ATOM 3584 CB VAL C 148 -0.634 6.315 -92.869 1.00 87.46 C +ATOM 3585 CG1 VAL C 148 -0.314 7.788 -92.628 1.00 93.42 C +ATOM 3586 CG2 VAL C 148 0.605 5.564 -93.344 1.00 70.21 C +ATOM 3587 N LEU C 149 -2.738 3.976 -92.402 1.00 78.47 N +ATOM 3588 CA LEU C 149 -3.129 2.640 -92.816 1.00 76.10 C +ATOM 3589 C LEU C 149 -2.256 2.175 -93.977 1.00 77.14 C +ATOM 3590 O LEU C 149 -1.669 2.993 -94.689 1.00 75.95 O +ATOM 3591 CB LEU C 149 -4.595 2.609 -93.235 1.00 72.06 C +ATOM 3592 CG LEU C 149 -5.635 3.225 -92.300 1.00 75.94 C +ATOM 3593 CD1 LEU C 149 -6.997 3.204 -92.973 1.00 70.23 C +ATOM 3594 CD2 LEU C 149 -5.680 2.498 -90.963 1.00 79.37 C +ATOM 3595 N PRO C 150 -2.171 0.864 -94.204 1.00 80.41 N +ATOM 3596 CA PRO C 150 -1.511 0.372 -95.419 1.00 80.86 C +ATOM 3597 C PRO C 150 -2.172 0.928 -96.673 1.00 76.71 C +ATOM 3598 O PRO C 150 -3.196 1.615 -96.629 1.00 75.77 O +ATOM 3599 CB PRO C 150 -1.664 -1.149 -95.318 1.00 74.76 C +ATOM 3600 CG PRO C 150 -1.767 -1.412 -93.850 1.00 74.12 C +ATOM 3601 CD PRO C 150 -2.520 -0.235 -93.284 1.00 75.07 C +ATOM 3602 N ASP C 151 -1.543 0.649 -97.812 1.00 78.85 N +ATOM 3603 CA ASP C 151 -2.113 1.052 -99.086 1.00 75.31 C +ATOM 3604 C ASP C 151 -3.484 0.410 -99.274 1.00 77.52 C +ATOM 3605 O ASP C 151 -3.889 -0.498 -98.541 1.00 82.85 O +ATOM 3606 CB ASP C 151 -1.196 0.651-100.239 1.00 71.66 C +ATOM 3607 CG ASP C 151 0.073 1.460-100.275 1.00 76.00 C +ATOM 3608 OD1 ASP C 151 0.067 2.593 -99.745 1.00 82.82 O +ATOM 3609 OD2 ASP C 151 1.073 0.964-100.834 1.00 71.74 O +ATOM 3610 N LEU C 152 -4.200 0.880-100.280 1.00 64.57 N +ATOM 3611 CA LEU C 152 -5.532 0.369-100.533 1.00 69.77 C +ATOM 3612 C LEU C 152 -5.562 -0.359-101.873 1.00 72.89 C +ATOM 3613 O LEU C 152 -4.525 -0.616-102.495 1.00 79.07 O +ATOM 3614 CB LEU C 152 -6.543 1.512-100.474 1.00 71.72 C +ATOM 3615 CG LEU C 152 -6.640 2.179 -99.102 1.00 72.38 C +ATOM 3616 CD1 LEU C 152 -5.749 3.415 -99.038 1.00 61.54 C +ATOM 3617 CD2 LEU C 152 -8.087 2.521 -98.785 1.00 65.43 C +ATOM 3618 N THR C 153 -6.770 -0.694-102.311 1.00 74.12 N +ATOM 3619 CA THR C 153 -7.039 -1.387-103.562 1.00 76.82 C +ATOM 3620 C THR C 153 -8.539 -1.356-103.783 1.00 78.82 C +ATOM 3621 O THR C 153 -9.311 -1.314-102.823 1.00 76.43 O +ATOM 3622 CB THR C 153 -6.532 -2.839-103.555 1.00 75.02 C +ATOM 3623 OG1 THR C 153 -7.051 -3.535-104.695 1.00 73.99 O +ATOM 3624 CG2 THR C 153 -6.967 -3.567-102.301 1.00 68.89 C +ATOM 3625 N GLU C 154 -8.944 -1.342-105.057 1.00 81.53 N +ATOM 3626 CA GLU C 154 -10.367 -1.322-105.383 1.00 85.63 C +ATOM 3627 C GLU C 154 -11.129 -2.439-104.679 1.00 83.81 C +ATOM 3628 O GLU C 154 -12.342 -2.314-104.467 1.00 79.62 O +ATOM 3629 CB GLU C 154 -10.566 -1.418-106.897 1.00 86.78 C +ATOM 3630 CG GLU C 154 -11.318 -0.238-107.495 1.00 89.61 C +ATOM 3631 CD GLU C 154 -12.550 -0.664-108.275 1.00 91.08 C +ATOM 3632 OE1 GLU C 154 -13.648 -0.137-107.995 1.00 84.65 O +ATOM 3633 OE2 GLU C 154 -12.417 -1.533-109.165 1.00 91.29 O +ATOM 3634 N GLU C 155 -10.441 -3.522-104.304 1.00 79.99 N +ATOM 3635 CA GLU C 155 -11.050 -4.574-103.502 1.00 73.50 C +ATOM 3636 C GLU C 155 -11.272 -4.140-102.056 1.00 78.44 C +ATOM 3637 O GLU C 155 -12.064 -4.773-101.348 1.00 75.30 O +ATOM 3638 CB GLU C 155 -10.174 -5.831-103.554 1.00 68.83 C +ATOM 3639 CG GLU C 155 -10.893 -7.130-103.194 1.00 80.22 C +ATOM 3640 CD GLU C 155 -10.723 -7.519-101.733 1.00 83.61 C +ATOM 3641 OE1 GLU C 155 -10.004 -6.802-101.003 1.00 85.43 O +ATOM 3642 OE2 GLU C 155 -11.315 -8.538-101.313 1.00 73.08 O +ATOM 3643 N ASP C 156 -10.618 -3.061-101.607 1.00 79.65 N +ATOM 3644 CA ASP C 156 -10.765 -2.566-100.241 1.00 77.24 C +ATOM 3645 C ASP C 156 -11.821 -1.480-100.098 1.00 73.84 C +ATOM 3646 O ASP C 156 -12.183 -1.140 -98.965 1.00 65.92 O +ATOM 3647 CB ASP C 156 -9.433 -2.014 -99.719 1.00 74.97 C +ATOM 3648 CG ASP C 156 -8.469 -3.104 -99.318 1.00 77.83 C +ATOM 3649 OD1 ASP C 156 -8.936 -4.217 -98.994 1.00 81.16 O +ATOM 3650 OD2 ASP C 156 -7.246 -2.841 -99.305 1.00 75.39 O +ATOM 3651 N THR C 157 -12.304 -0.915-101.201 1.00 73.44 N +ATOM 3652 CA THR C 157 -13.433 0.001-101.141 1.00 69.60 C +ATOM 3653 C THR C 157 -14.720 -0.755-100.823 1.00 69.48 C +ATOM 3654 O THR C 157 -14.820 -1.975-100.990 1.00 74.27 O +ATOM 3655 CB THR C 157 -13.599 0.755-102.464 1.00 68.58 C +ATOM 3656 OG1 THR C 157 -13.024 -0.009-103.534 1.00 72.26 O +ATOM 3657 CG2 THR C 157 -12.945 2.125-102.397 1.00 66.87 C +ATOM 3658 N LEU C 158 -15.718 -0.014-100.349 1.00 59.40 N +ATOM 3659 CA LEU C 158 -16.990 -0.651-100.041 1.00 60.69 C +ATOM 3660 C LEU C 158 -17.857 -0.764-101.291 1.00 66.90 C +ATOM 3661 O LEU C 158 -18.358 -1.845-101.613 1.00 67.69 O +ATOM 3662 CB LEU C 158 -17.719 0.127 -98.946 1.00 56.23 C +ATOM 3663 CG LEU C 158 -18.284 -0.703 -97.790 1.00 58.88 C +ATOM 3664 CD1 LEU C 158 -19.494 -0.001 -97.208 1.00 55.36 C +ATOM 3665 CD2 LEU C 158 -18.623 -2.138 -98.201 1.00 58.41 C +ATOM 3666 N PHE C 159 -18.031 0.342-102.009 1.00 63.89 N +ATOM 3667 CA PHE C 159 -18.855 0.380-103.207 1.00 53.94 C +ATOM 3668 C PHE C 159 -18.425 1.583-104.030 1.00 55.40 C +ATOM 3669 O PHE C 159 -17.966 2.591-103.487 1.00 55.26 O +ATOM 3670 CB PHE C 159 -20.361 0.459-102.898 1.00 51.26 C +ATOM 3671 CG PHE C 159 -20.762 1.542-101.902 1.00 56.92 C +ATOM 3672 CD1 PHE C 159 -19.892 2.030-100.934 1.00 63.01 C +ATOM 3673 CD2 PHE C 159 -22.041 2.062-101.942 1.00 57.99 C +ATOM 3674 CE1 PHE C 159 -20.283 3.005-100.041 1.00 64.06 C +ATOM 3675 CE2 PHE C 159 -22.437 3.040-101.050 1.00 58.69 C +ATOM 3676 CZ PHE C 159 -21.556 3.511-100.099 1.00 59.43 C +ATOM 3677 N ASN C 160 -18.612 1.482-105.341 1.00 61.22 N +ATOM 3678 CA ASN C 160 -18.168 2.525-106.263 1.00 61.08 C +ATOM 3679 C ASN C 160 -19.197 3.647-106.308 1.00 54.94 C +ATOM 3680 O ASN C 160 -20.164 3.596-107.067 1.00 58.04 O +ATOM 3681 CB ASN C 160 -17.910 1.941-107.645 1.00 69.38 C +ATOM 3682 CG ASN C 160 -16.818 0.881-107.632 1.00 84.57 C +ATOM 3683 OD1 ASN C 160 -16.452 0.361-106.572 1.00 78.86 O +ATOM 3684 ND2 ASN C 160 -16.269 0.582-108.805 1.00 81.66 N +ATOM 3685 N LEU C 161 -18.982 4.661-105.459 1.00 48.05 N +ATOM 3686 CA LEU C 161 -19.713 5.932-105.395 1.00 49.66 C +ATOM 3687 C LEU C 161 -20.760 6.174-106.482 1.00 51.20 C +ATOM 3688 O LEU C 161 -21.888 6.581-106.181 1.00 46.19 O +ATOM 3689 CB LEU C 161 -18.710 7.090-105.424 1.00 48.61 C +ATOM 3690 CG LEU C 161 -19.218 8.480-105.819 1.00 44.84 C +ATOM 3691 CD1 LEU C 161 -20.172 9.061-104.780 1.00 44.55 C +ATOM 3692 CD2 LEU C 161 -18.044 9.412-106.056 1.00 45.01 C +ATOM 3693 N ASN C 162 -20.400 5.951-107.749 1.00 54.45 N +ATOM 3694 CA ASN C 162 -21.356 6.095-108.841 1.00 53.31 C +ATOM 3695 C ASN C 162 -22.559 5.161-108.702 1.00 57.62 C +ATOM 3696 O ASN C 162 -23.544 5.328-109.432 1.00 55.39 O +ATOM 3697 CB ASN C 162 -20.639 5.851-110.175 1.00 49.02 C +ATOM 3698 CG ASN C 162 -21.484 6.233-111.380 1.00 53.69 C +ATOM 3699 OD1 ASN C 162 -22.283 7.168-111.323 1.00 56.17 O +ATOM 3700 ND2 ASN C 162 -21.306 5.508-112.483 1.00 55.38 N +ATOM 3701 N ALA C 163 -22.528 4.218-107.756 1.00 57.08 N +ATOM 3702 CA ALA C 163 -23.603 3.254-107.577 1.00 52.54 C +ATOM 3703 C ALA C 163 -24.464 3.508-106.352 1.00 48.17 C +ATOM 3704 O ALA C 163 -25.522 2.885-106.228 1.00 51.08 O +ATOM 3705 CB ALA C 163 -23.034 1.829-107.493 1.00 58.59 C +ATOM 3706 N GLU C 164 -24.054 4.391-105.446 1.00 47.40 N +ATOM 3707 CA GLU C 164 -24.964 4.807-104.389 1.00 40.97 C +ATOM 3708 C GLU C 164 -25.772 6.028-104.786 1.00 42.28 C +ATOM 3709 O GLU C 164 -26.935 6.148-104.387 1.00 40.18 O +ATOM 3710 CB GLU C 164 -24.204 5.112-103.096 1.00 38.00 C +ATOM 3711 CG GLU C 164 -25.123 5.585-101.978 1.00 47.09 C +ATOM 3712 CD GLU C 164 -24.412 5.822-100.662 1.00 56.20 C +ATOM 3713 OE1 GLU C 164 -23.189 6.066-100.689 1.00 61.17 O +ATOM 3714 OE2 GLU C 164 -25.084 5.778 -99.603 1.00 46.33 O +ATOM 3715 N ILE C 165 -25.207 6.902-105.622 1.00 43.75 N +ATOM 3716 CA ILE C 165 -25.941 8.062-106.109 1.00 41.32 C +ATOM 3717 C ILE C 165 -27.078 7.685-107.040 1.00 42.91 C +ATOM 3718 O ILE C 165 -27.961 8.514-107.292 1.00 38.00 O +ATOM 3719 CB ILE C 165 -24.965 9.019-106.819 1.00 42.31 C +ATOM 3720 CG1 ILE C 165 -24.355 8.353-108.063 1.00 55.09 C +ATOM 3721 CG2 ILE C 165 -23.851 9.429-105.865 1.00 38.00 C +ATOM 3722 CD1 ILE C 165 -24.999 8.737-109.413 1.00 51.49 C +ATOM 3723 N ARG C 166 -27.110 6.437-107.503 1.00 46.02 N +ATOM 3724 CA ARG C 166 -28.155 5.945-108.386 1.00 45.42 C +ATOM 3725 C ARG C 166 -29.305 5.316-107.609 1.00 42.70 C +ATOM 3726 O ARG C 166 -30.273 4.851-108.218 1.00 43.70 O +ATOM 3727 CB ARG C 166 -27.587 4.912-109.371 1.00 51.28 C +ATOM 3728 CG ARG C 166 -28.534 4.579-110.542 1.00 58.89 C +ATOM 3729 CD ARG C 166 -28.014 3.447-111.399 1.00 66.45 C +ATOM 3730 NE ARG C 166 -26.618 3.577-111.785 1.00 72.46 N +ATOM 3731 CZ ARG C 166 -25.677 2.799-111.261 1.00 67.01 C +ATOM 3732 NH1 ARG C 166 -26.011 1.896-110.347 1.00 69.68 N +ATOM 3733 NH2 ARG C 166 -24.412 2.920-111.628 1.00 58.73 N +ATOM 3734 N LEU C 167 -29.214 5.274-106.282 1.00 41.33 N +ATOM 3735 CA LEU C 167 -30.281 4.734-105.452 1.00 38.06 C +ATOM 3736 C LEU C 167 -31.217 5.807-104.937 1.00 38.65 C +ATOM 3737 O LEU C 167 -32.358 5.498-104.568 1.00 38.00 O +ATOM 3738 CB LEU C 167 -29.696 3.986-104.252 1.00 38.00 C +ATOM 3739 CG LEU C 167 -29.471 2.487-104.414 1.00 38.00 C +ATOM 3740 CD1 LEU C 167 -28.497 2.196-105.538 1.00 43.63 C +ATOM 3741 CD2 LEU C 167 -28.968 1.916-103.106 1.00 39.44 C +ATOM 3742 N TYR C 168 -30.778 7.043-104.954 1.00 41.30 N +ATOM 3743 CA TYR C 168 -31.526 8.180-104.471 1.00 41.26 C +ATOM 3744 C TYR C 168 -32.238 8.854-105.631 1.00 43.40 C +ATOM 3745 O TYR C 168 -31.853 8.690-106.792 1.00 44.31 O +ATOM 3746 CB TYR C 168 -30.577 9.167-103.774 1.00 39.51 C +ATOM 3747 CG TYR C 168 -30.107 8.700-102.406 1.00 40.05 C +ATOM 3748 CD1 TYR C 168 -29.248 7.614-102.276 1.00 40.65 C +ATOM 3749 CD2 TYR C 168 -30.541 9.328-101.246 1.00 45.04 C +ATOM 3750 CE1 TYR C 168 -28.826 7.177-101.036 1.00 40.14 C +ATOM 3751 CE2 TYR C 168 -30.125 8.892 -99.999 1.00 47.20 C +ATOM 3752 CZ TYR C 168 -29.268 7.816 -99.903 1.00 48.64 C +ATOM 3753 OH TYR C 168 -28.843 7.379 -98.668 1.00 70.86 O +ATOM 3754 N PRO C 169 -33.289 9.620-105.355 1.00 43.75 N +ATOM 3755 CA PRO C 169 -34.028 10.286-106.437 1.00 50.22 C +ATOM 3756 C PRO C 169 -33.182 11.257-107.239 1.00 55.69 C +ATOM 3757 O PRO C 169 -32.003 11.473-106.945 1.00 60.96 O +ATOM 3758 CB PRO C 169 -35.147 11.024-105.692 1.00 52.65 C +ATOM 3759 CG PRO C 169 -34.669 11.135-104.290 1.00 54.99 C +ATOM 3760 CD PRO C 169 -33.898 9.883-104.044 1.00 49.13 C +ATOM 3761 N LYS C 170 -33.782 11.865-108.252 1.00 52.71 N +ATOM 3762 CA LYS C 170 -33.039 12.812-109.070 1.00 51.31 C +ATOM 3763 C LYS C 170 -32.604 14.061-108.291 1.00 57.60 C +ATOM 3764 O LYS C 170 -31.924 14.902-108.883 1.00 70.42 O +ATOM 3765 CB LYS C 170 -33.888 13.198-110.287 1.00 62.91 C +ATOM 3766 CG LYS C 170 -34.229 12.023-111.217 1.00 65.89 C +ATOM 3767 CD LYS C 170 -34.650 12.488-112.618 1.00 62.35 C +ATOM 3768 CE LYS C 170 -33.479 12.974-113.462 1.00 63.30 C +ATOM 3769 NZ LYS C 170 -32.447 11.916-113.624 1.00 70.20 N +ATOM 3770 N ALA C 171 -32.980 14.199-107.011 1.00 55.23 N +ATOM 3771 CA ALA C 171 -32.549 15.278-106.116 1.00 55.31 C +ATOM 3772 C ALA C 171 -32.999 16.661-106.590 1.00 68.94 C +ATOM 3773 O ALA C 171 -33.438 16.828-107.734 1.00 67.25 O +ATOM 3774 CB ALA C 171 -31.025 15.261-105.916 1.00 48.18 C +ATOM 3775 N ALA C 172 -32.891 17.659-105.711 1.00 74.56 N +ATOM 3776 CA ALA C 172 -33.279 19.034-106.031 1.00 71.93 C +ATOM 3777 C ALA C 172 -32.148 20.002-105.694 1.00 70.17 C +ATOM 3778 O ALA C 172 -30.972 19.641-105.772 1.00 65.80 O +ATOM 3779 CB ALA C 172 -34.562 19.424-105.284 1.00 52.93 C +ATOM 3780 N SER C 196 -16.159 19.406-107.497 1.00101.44 N +ATOM 3781 CA SER C 196 -16.884 18.171-107.756 1.00 92.96 C +ATOM 3782 C SER C 196 -17.393 17.579-106.445 1.00 87.77 C +ATOM 3783 O SER C 196 -18.444 16.936-106.413 1.00 85.80 O +ATOM 3784 CB SER C 196 -15.997 17.162-108.498 1.00 82.11 C +ATOM 3785 OG SER C 196 -14.900 16.736-107.704 1.00 74.43 O +ATOM 3786 N GLU C 197 -16.656 17.822-105.363 1.00 95.01 N +ATOM 3787 CA GLU C 197 -16.952 17.215-104.062 1.00 95.96 C +ATOM 3788 C GLU C 197 -17.935 18.058-103.246 1.00 80.57 C +ATOM 3789 O GLU C 197 -17.741 18.307-102.056 1.00 63.28 O +ATOM 3790 CB GLU C 197 -15.653 16.979-103.293 1.00 86.24 C +ATOM 3791 CG GLU C 197 -14.802 15.825-103.833 1.00 81.86 C +ATOM 3792 CD GLU C 197 -15.616 14.562-104.090 1.00 81.78 C +ATOM 3793 OE1 GLU C 197 -16.293 14.082-103.153 1.00 71.56 O +ATOM 3794 OE2 GLU C 197 -15.581 14.056-105.237 1.00 71.78 O +ATOM 3795 N SER C 198 -19.012 18.498-103.896 1.00 81.17 N +ATOM 3796 CA SER C 198 -20.102 19.204-103.237 1.00 76.97 C +ATOM 3797 C SER C 198 -21.212 18.264-102.784 1.00 74.87 C +ATOM 3798 O SER C 198 -22.323 18.724-102.497 1.00 65.25 O +ATOM 3799 CB SER C 198 -20.682 20.280-104.157 1.00 81.53 C +ATOM 3800 OG SER C 198 -21.783 20.924-103.538 1.00 75.01 O +ATOM 3801 N TYR C 199 -20.946 16.960-102.761 1.00 76.86 N +ATOM 3802 CA TYR C 199 -21.907 16.002-102.251 1.00 64.72 C +ATOM 3803 C TYR C 199 -22.090 16.210-100.751 1.00 59.28 C +ATOM 3804 O TYR C 199 -21.140 16.564-100.046 1.00 64.52 O +ATOM 3805 CB TYR C 199 -21.433 14.577-102.510 1.00 62.11 C +ATOM 3806 CG TYR C 199 -21.145 14.267-103.960 1.00 61.71 C +ATOM 3807 CD1 TYR C 199 -21.857 14.877-104.982 1.00 62.03 C +ATOM 3808 CD2 TYR C 199 -20.143 13.370-104.303 1.00 62.45 C +ATOM 3809 CE1 TYR C 199 -21.587 14.590-106.304 1.00 71.25 C +ATOM 3810 CE2 TYR C 199 -19.864 13.079-105.616 1.00 63.40 C +ATOM 3811 CZ TYR C 199 -20.587 13.690-106.615 1.00 72.47 C +ATOM 3812 OH TYR C 199 -20.303 13.397-107.932 1.00 75.32 O +ATOM 3813 N PRO C 200 -23.291 15.962-100.235 1.00 51.36 N +ATOM 3814 CA PRO C 200 -23.538 16.170 -98.806 1.00 51.05 C +ATOM 3815 C PRO C 200 -22.577 15.363 -97.948 1.00 55.98 C +ATOM 3816 O PRO C 200 -21.995 14.366 -98.380 1.00 58.67 O +ATOM 3817 CB PRO C 200 -24.981 15.693 -98.628 1.00 55.84 C +ATOM 3818 CG PRO C 200 -25.598 15.884 -99.981 1.00 63.93 C +ATOM 3819 CD PRO C 200 -24.507 15.555-100.957 1.00 58.34 C +ATOM 3820 N ASN C 201 -22.388 15.837 -96.712 1.00 56.51 N +ATOM 3821 CA ASN C 201 -21.410 15.213 -95.828 1.00 56.42 C +ATOM 3822 C ASN C 201 -21.747 13.759 -95.533 1.00 55.77 C +ATOM 3823 O ASN C 201 -20.838 12.932 -95.389 1.00 51.99 O +ATOM 3824 CB ASN C 201 -21.302 16.004 -94.528 1.00 56.42 C +ATOM 3825 CG ASN C 201 -20.792 17.394 -94.749 1.00 56.77 C +ATOM 3826 OD1 ASN C 201 -20.104 17.658 -95.733 1.00 57.45 O +ATOM 3827 ND2 ASN C 201 -21.133 18.303 -93.844 1.00 63.17 N +ATOM 3828 N TRP C 202 -23.033 13.418 -95.446 1.00 49.92 N +ATOM 3829 CA TRP C 202 -23.382 12.029 -95.183 1.00 46.65 C +ATOM 3830 C TRP C 202 -22.998 11.120 -96.335 1.00 47.34 C +ATOM 3831 O TRP C 202 -22.896 9.906 -96.144 1.00 54.09 O +ATOM 3832 CB TRP C 202 -24.873 11.900 -94.901 1.00 47.45 C +ATOM 3833 CG TRP C 202 -25.720 12.239 -96.067 1.00 52.64 C +ATOM 3834 CD1 TRP C 202 -26.293 13.442 -96.328 1.00 56.91 C +ATOM 3835 CD2 TRP C 202 -26.102 11.369 -97.139 1.00 53.32 C +ATOM 3836 NE1 TRP C 202 -27.017 13.381 -97.493 1.00 55.33 N +ATOM 3837 CE2 TRP C 202 -26.912 12.119 -98.013 1.00 54.03 C +ATOM 3838 CE3 TRP C 202 -25.839 10.031 -97.444 1.00 52.33 C +ATOM 3839 CZ2 TRP C 202 -27.460 11.577 -99.170 1.00 52.96 C +ATOM 3840 CZ3 TRP C 202 -26.382 9.497 -98.595 1.00 53.49 C +ATOM 3841 CH2 TRP C 202 -27.181 10.269 -99.444 1.00 50.91 C +ATOM 3842 N LEU C 203 -22.771 11.677 -97.517 1.00 47.04 N +ATOM 3843 CA LEU C 203 -22.332 10.876 -98.647 1.00 46.69 C +ATOM 3844 C LEU C 203 -20.818 10.739 -98.665 1.00 48.30 C +ATOM 3845 O LEU C 203 -20.295 9.642 -98.875 1.00 51.72 O +ATOM 3846 CB LEU C 203 -22.821 11.497 -99.955 1.00 48.99 C +ATOM 3847 CG LEU C 203 -22.548 10.702-101.228 1.00 43.78 C +ATOM 3848 CD1 LEU C 203 -22.760 9.220-100.998 1.00 43.50 C +ATOM 3849 CD2 LEU C 203 -23.433 11.208-102.347 1.00 48.60 C +ATOM 3850 N ARG C 204 -20.105 11.848 -98.453 1.00 47.73 N +ATOM 3851 CA ARG C 204 -18.657 11.774 -98.307 1.00 48.38 C +ATOM 3852 C ARG C 204 -18.271 10.830 -97.177 1.00 51.45 C +ATOM 3853 O ARG C 204 -17.235 10.161 -97.250 1.00 51.87 O +ATOM 3854 CB ARG C 204 -18.081 13.171 -98.065 1.00 54.06 C +ATOM 3855 CG ARG C 204 -16.844 13.497 -98.900 1.00 65.52 C +ATOM 3856 CD ARG C 204 -17.164 14.481-100.024 1.00 73.79 C +ATOM 3857 NE ARG C 204 -17.831 15.680 -99.522 1.00 73.45 N +ATOM 3858 CZ ARG C 204 -17.198 16.753 -99.056 1.00 74.36 C +ATOM 3859 NH1 ARG C 204 -17.893 17.795 -98.615 1.00 68.63 N +ATOM 3860 NH2 ARG C 204 -15.870 16.784 -99.028 1.00 71.89 N +ATOM 3861 N PHE C 205 -19.116 10.736 -96.148 1.00 50.11 N +ATOM 3862 CA PHE C 205 -18.877 9.803 -95.053 1.00 47.49 C +ATOM 3863 C PHE C 205 -18.988 8.358 -95.522 1.00 45.94 C +ATOM 3864 O PHE C 205 -18.158 7.518 -95.154 1.00 46.08 O +ATOM 3865 CB PHE C 205 -19.862 10.115 -93.925 1.00 45.80 C +ATOM 3866 CG PHE C 205 -20.061 9.002 -92.942 1.00 48.14 C +ATOM 3867 CD1 PHE C 205 -19.002 8.503 -92.204 1.00 49.73 C +ATOM 3868 CD2 PHE C 205 -21.329 8.488 -92.719 1.00 47.00 C +ATOM 3869 CE1 PHE C 205 -19.200 7.491 -91.286 1.00 48.31 C +ATOM 3870 CE2 PHE C 205 -21.535 7.479 -91.801 1.00 42.65 C +ATOM 3871 CZ PHE C 205 -20.468 6.980 -91.083 1.00 47.72 C +ATOM 3872 N HIS C 206 -19.972 8.062 -96.376 1.00 48.46 N +ATOM 3873 CA HIS C 206 -20.207 6.683 -96.800 1.00 50.00 C +ATOM 3874 C HIS C 206 -19.088 6.170 -97.700 1.00 49.32 C +ATOM 3875 O HIS C 206 -18.618 5.039 -97.531 1.00 48.30 O +ATOM 3876 CB HIS C 206 -21.551 6.577 -97.521 1.00 47.71 C +ATOM 3877 CG HIS C 206 -22.730 6.562 -96.602 1.00 44.80 C +ATOM 3878 ND1 HIS C 206 -23.856 7.323 -96.826 1.00 52.49 N +ATOM 3879 CD2 HIS C 206 -22.956 5.890 -95.450 1.00 46.17 C +ATOM 3880 CE1 HIS C 206 -24.728 7.116 -95.856 1.00 52.39 C +ATOM 3881 NE2 HIS C 206 -24.206 6.250 -95.007 1.00 50.77 N +ATOM 3882 N ILE C 207 -18.652 6.981 -98.667 1.00 49.20 N +ATOM 3883 CA ILE C 207 -17.638 6.521 -99.607 1.00 54.13 C +ATOM 3884 C ILE C 207 -16.290 6.338 -98.923 1.00 55.20 C +ATOM 3885 O ILE C 207 -15.422 5.630 -99.451 1.00 53.47 O +ATOM 3886 CB ILE C 207 -17.529 7.484-100.807 1.00 53.39 C +ATOM 3887 CG1 ILE C 207 -17.258 8.908-100.333 1.00 54.09 C +ATOM 3888 CG2 ILE C 207 -18.797 7.446-101.649 1.00 44.38 C +ATOM 3889 CD1 ILE C 207 -17.208 9.912-101.461 1.00 52.06 C +ATOM 3890 N GLY C 208 -16.082 6.972 -97.766 1.00 50.57 N +ATOM 3891 CA GLY C 208 -14.832 6.834 -97.041 1.00 57.51 C +ATOM 3892 C GLY C 208 -14.703 5.589 -96.189 1.00 55.39 C +ATOM 3893 O GLY C 208 -13.617 5.323 -95.665 1.00 54.21 O +ATOM 3894 N ILE C 209 -15.771 4.803 -96.065 1.00 52.71 N +ATOM 3895 CA ILE C 209 -15.730 3.569 -95.292 1.00 48.00 C +ATOM 3896 C ILE C 209 -14.913 2.545 -96.065 1.00 50.72 C +ATOM 3897 O ILE C 209 -15.402 1.945 -97.028 1.00 57.65 O +ATOM 3898 CB ILE C 209 -17.138 3.020 -94.996 1.00 44.55 C +ATOM 3899 CG1 ILE C 209 -18.062 4.101 -94.451 1.00 46.34 C +ATOM 3900 CG2 ILE C 209 -17.066 1.903 -93.982 1.00 47.22 C +ATOM 3901 CD1 ILE C 209 -19.475 3.604 -94.247 1.00 38.00 C +ATOM 3902 N ASN C 210 -13.649 2.386 -95.701 1.00 48.34 N +ATOM 3903 CA ASN C 210 -12.801 1.390 -96.329 1.00 50.56 C +ATOM 3904 C ASN C 210 -12.645 0.177 -95.409 1.00 52.04 C +ATOM 3905 O ASN C 210 -13.304 0.066 -94.370 1.00 48.74 O +ATOM 3906 CB ASN C 210 -11.460 2.013 -96.703 1.00 60.75 C +ATOM 3907 CG ASN C 210 -10.664 2.437 -95.496 1.00 65.93 C +ATOM 3908 OD1 ASN C 210 -11.187 3.076 -94.585 1.00 61.55 O +ATOM 3909 ND2 ASN C 210 -9.387 2.076 -95.477 1.00 70.12 N +ATOM 3910 N ARG C 211 -11.748 -0.738 -95.794 1.00 60.57 N +ATOM 3911 CA ARG C 211 -11.582 -2.005 -95.081 1.00 62.49 C +ATOM 3912 C ARG C 211 -11.150 -1.797 -93.632 1.00 60.60 C +ATOM 3913 O ARG C 211 -11.615 -2.503 -92.731 1.00 64.50 O +ATOM 3914 CB ARG C 211 -10.572 -2.890 -95.826 1.00 67.16 C +ATOM 3915 CG ARG C 211 -9.965 -4.029 -94.996 1.00 64.67 C +ATOM 3916 CD ARG C 211 -9.178 -5.031 -95.843 1.00 62.01 C +ATOM 3917 NE ARG C 211 -10.011 -5.622 -96.889 1.00 73.09 N +ATOM 3918 CZ ARG C 211 -10.659 -6.779 -96.779 1.00 71.89 C +ATOM 3919 NH1 ARG C 211 -10.576 -7.491 -95.663 1.00 66.13 N +ATOM 3920 NH2 ARG C 211 -11.397 -7.224 -97.789 1.00 68.63 N +ATOM 3921 N TYR C 212 -10.255 -0.845 -93.386 1.00 56.58 N +ATOM 3922 CA TYR C 212 -9.652 -0.722 -92.065 1.00 55.38 C +ATOM 3923 C TYR C 212 -10.445 0.222 -91.166 1.00 53.62 C +ATOM 3924 O TYR C 212 -11.178 -0.229 -90.282 1.00 48.04 O +ATOM 3925 CB TYR C 212 -8.197 -0.275 -92.212 1.00 60.35 C +ATOM 3926 CG TYR C 212 -7.418 -1.121 -93.204 1.00 60.63 C +ATOM 3927 CD1 TYR C 212 -7.008 -2.410 -92.883 1.00 58.12 C +ATOM 3928 CD2 TYR C 212 -7.106 -0.635 -94.468 1.00 67.61 C +ATOM 3929 CE1 TYR C 212 -6.303 -3.188 -93.792 1.00 59.84 C +ATOM 3930 CE2 TYR C 212 -6.401 -1.408 -95.383 1.00 72.07 C +ATOM 3931 CZ TYR C 212 -6.004 -2.682 -95.039 1.00 65.33 C +ATOM 3932 OH TYR C 212 -5.304 -3.447 -95.943 1.00 62.38 O +ATOM 3933 N GLU C 213 -10.280 1.525 -91.354 1.00 63.41 N +ATOM 3934 CA GLU C 213 -11.012 2.500 -90.561 1.00 61.53 C +ATOM 3935 C GLU C 213 -12.399 2.744 -91.159 1.00 57.95 C +ATOM 3936 O GLU C 213 -12.666 2.445 -92.327 1.00 59.59 O +ATOM 3937 CB GLU C 213 -10.224 3.811 -90.462 1.00 67.43 C +ATOM 3938 CG GLU C 213 -10.136 4.618 -91.765 1.00 67.45 C +ATOM 3939 CD GLU C 213 -9.034 5.676 -91.749 1.00 72.17 C +ATOM 3940 OE1 GLU C 213 -8.602 6.093 -90.651 1.00 74.43 O +ATOM 3941 OE2 GLU C 213 -8.612 6.107 -92.843 1.00 71.46 O +ATOM 3942 N LEU C 214 -13.302 3.257 -90.318 1.00 52.88 N +ATOM 3943 CA LEU C 214 -14.603 3.724 -90.779 1.00 46.88 C +ATOM 3944 C LEU C 214 -14.565 5.170 -91.273 1.00 57.73 C +ATOM 3945 O LEU C 214 -15.506 5.605 -91.949 1.00 52.70 O +ATOM 3946 CB LEU C 214 -15.632 3.571 -89.659 1.00 38.00 C +ATOM 3947 CG LEU C 214 -17.096 3.770 -90.026 1.00 38.00 C +ATOM 3948 CD1 LEU C 214 -17.736 2.442 -90.282 1.00 38.00 C +ATOM 3949 CD2 LEU C 214 -17.802 4.477 -88.901 1.00 38.00 C +ATOM 3950 N TYR C 215 -13.509 5.919 -90.940 1.00 64.96 N +ATOM 3951 CA TYR C 215 -13.302 7.298 -91.372 1.00 63.40 C +ATOM 3952 C TYR C 215 -11.870 7.707 -91.050 1.00 65.28 C +ATOM 3953 O TYR C 215 -11.325 7.294 -90.024 1.00 63.29 O +ATOM 3954 CB TYR C 215 -14.287 8.266 -90.698 1.00 59.90 C +ATOM 3955 CG TYR C 215 -14.356 8.184 -89.180 1.00 64.25 C +ATOM 3956 CD1 TYR C 215 -15.237 7.312 -88.553 1.00 66.68 C +ATOM 3957 CD2 TYR C 215 -13.553 8.987 -88.374 1.00 63.22 C +ATOM 3958 CE1 TYR C 215 -15.315 7.236 -87.163 1.00 66.48 C +ATOM 3959 CE2 TYR C 215 -13.625 8.916 -86.980 1.00 63.01 C +ATOM 3960 CZ TYR C 215 -14.509 8.036 -86.384 1.00 58.83 C +ATOM 3961 OH TYR C 215 -14.602 7.942 -85.012 1.00 50.26 O +ATOM 3962 N SER C 216 -11.276 8.525 -91.922 1.00 69.32 N +ATOM 3963 CA SER C 216 -9.895 8.970 -91.750 1.00 73.78 C +ATOM 3964 C SER C 216 -9.712 9.671 -90.402 1.00 74.66 C +ATOM 3965 O SER C 216 -10.672 10.120 -89.768 1.00 78.60 O +ATOM 3966 CB SER C 216 -9.474 9.882 -92.904 1.00 76.04 C +ATOM 3967 OG SER C 216 -9.931 11.210 -92.726 1.00 84.35 O +ATOM 3968 N ARG C 217 -8.453 9.737 -89.953 1.00 68.13 N +ATOM 3969 CA ARG C 217 -8.162 10.228 -88.605 1.00 72.24 C +ATOM 3970 C ARG C 217 -8.704 11.632 -88.381 1.00 75.09 C +ATOM 3971 O ARG C 217 -9.550 11.852 -87.507 1.00 68.44 O +ATOM 3972 CB ARG C 217 -6.659 10.180 -88.335 1.00 60.66 C +ATOM 3973 CG ARG C 217 -6.296 9.251 -87.200 1.00 58.39 C +ATOM 3974 CD ARG C 217 -4.916 8.704 -87.394 1.00 59.83 C +ATOM 3975 NE ARG C 217 -4.790 7.374 -86.813 1.00 72.72 N +ATOM 3976 CZ ARG C 217 -3.662 6.674 -86.799 1.00 80.21 C +ATOM 3977 NH1 ARG C 217 -2.567 7.192 -87.331 1.00 80.20 N +ATOM 3978 NH2 ARG C 217 -3.628 5.467 -86.244 1.00 80.97 N +ATOM 3979 N HIS C 218 -8.243 12.595 -89.165 1.00 71.07 N +ATOM 3980 CA HIS C 218 -8.689 13.975 -89.028 1.00 77.25 C +ATOM 3981 C HIS C 218 -9.392 14.387 -90.317 1.00 78.07 C +ATOM 3982 O HIS C 218 -8.877 15.196 -91.089 1.00 82.57 O +ATOM 3983 CB HIS C 218 -7.526 14.904 -88.686 1.00 77.50 C +ATOM 3984 CG HIS C 218 -7.919 16.040 -87.794 1.00 79.98 C +ATOM 3985 ND1 HIS C 218 -8.946 16.906 -88.104 1.00 65.48 N +ATOM 3986 CD2 HIS C 218 -7.450 16.429 -86.584 1.00 76.62 C +ATOM 3987 CE1 HIS C 218 -9.080 17.792 -87.134 1.00 70.61 C +ATOM 3988 NE2 HIS C 218 -8.185 17.524 -86.198 1.00 72.65 N +ATOM 3989 N ASN C 219 -10.564 13.802 -90.555 1.00 78.71 N +ATOM 3990 CA ASN C 219 -11.355 14.147 -91.724 1.00 75.88 C +ATOM 3991 C ASN C 219 -12.035 15.499 -91.520 1.00 72.98 C +ATOM 3992 O ASN C 219 -12.449 15.835 -90.407 1.00 74.72 O +ATOM 3993 CB ASN C 219 -12.414 13.079 -91.991 1.00 72.11 C +ATOM 3994 CG ASN C 219 -12.751 12.944 -93.469 1.00 71.91 C +ATOM 3995 OD1 ASN C 219 -13.745 13.495 -93.951 1.00 63.77 O +ATOM 3996 ND2 ASN C 219 -11.923 12.199 -94.193 1.00 74.99 N +ATOM 3997 N PRO C 220 -12.171 16.292 -92.584 1.00 68.98 N +ATOM 3998 CA PRO C 220 -12.929 17.542 -92.470 1.00 66.28 C +ATOM 3999 C PRO C 220 -14.427 17.339 -92.571 1.00 68.29 C +ATOM 4000 O PRO C 220 -15.186 18.253 -92.221 1.00 66.40 O +ATOM 4001 CB PRO C 220 -12.410 18.370 -93.652 1.00 74.26 C +ATOM 4002 CG PRO C 220 -12.010 17.353 -94.675 1.00 80.95 C +ATOM 4003 CD PRO C 220 -11.605 16.097 -93.932 1.00 75.04 C +ATOM 4004 N VAL C 221 -14.873 16.161 -92.999 1.00 69.77 N +ATOM 4005 CA VAL C 221 -16.299 15.901 -93.146 1.00 66.02 C +ATOM 4006 C VAL C 221 -16.889 15.349 -91.863 1.00 61.67 C +ATOM 4007 O VAL C 221 -17.956 15.788 -91.430 1.00 61.20 O +ATOM 4008 CB VAL C 221 -16.543 14.940 -94.326 1.00 56.79 C +ATOM 4009 CG1 VAL C 221 -17.970 14.409 -94.295 1.00 56.86 C +ATOM 4010 CG2 VAL C 221 -16.256 15.636 -95.641 1.00 67.88 C +ATOM 4011 N ILE C 222 -16.187 14.409 -91.230 1.00 59.97 N +ATOM 4012 CA ILE C 222 -16.668 13.845 -89.973 1.00 65.94 C +ATOM 4013 C ILE C 222 -16.894 14.948 -88.953 1.00 72.53 C +ATOM 4014 O ILE C 222 -17.858 14.912 -88.176 1.00 69.63 O +ATOM 4015 CB ILE C 222 -15.680 12.786 -89.456 1.00 62.75 C +ATOM 4016 CG1 ILE C 222 -15.525 11.686 -90.495 1.00 59.52 C +ATOM 4017 CG2 ILE C 222 -16.177 12.186 -88.156 1.00 62.89 C +ATOM 4018 CD1 ILE C 222 -16.810 10.936 -90.726 1.00 64.14 C +ATOM 4019 N ALA C 223 -16.041 15.971 -88.970 1.00 71.04 N +ATOM 4020 CA ALA C 223 -16.295 17.138 -88.138 1.00 70.66 C +ATOM 4021 C ALA C 223 -17.536 17.876 -88.623 1.00 70.77 C +ATOM 4022 O ALA C 223 -18.421 18.214 -87.829 1.00 65.21 O +ATOM 4023 CB ALA C 223 -15.074 18.058 -88.138 1.00 71.41 C +ATOM 4024 N ALA C 224 -17.641 18.086 -89.939 1.00 68.29 N +ATOM 4025 CA ALA C 224 -18.786 18.801 -90.489 1.00 66.30 C +ATOM 4026 C ALA C 224 -20.045 17.947 -90.482 1.00 64.07 C +ATOM 4027 O ALA C 224 -21.156 18.486 -90.421 1.00 61.45 O +ATOM 4028 CB ALA C 224 -18.478 19.270 -91.908 1.00 63.27 C +ATOM 4029 N LEU C 225 -19.900 16.624 -90.569 1.00 60.43 N +ATOM 4030 CA LEU C 225 -21.071 15.759 -90.496 1.00 61.54 C +ATOM 4031 C LEU C 225 -21.758 15.903 -89.144 1.00 66.67 C +ATOM 4032 O LEU C 225 -22.994 15.920 -89.064 1.00 65.67 O +ATOM 4033 CB LEU C 225 -20.668 14.307 -90.775 1.00 57.56 C +ATOM 4034 CG LEU C 225 -21.748 13.257 -91.059 1.00 50.14 C +ATOM 4035 CD1 LEU C 225 -22.276 12.638 -89.781 1.00 63.58 C +ATOM 4036 CD2 LEU C 225 -22.894 13.866 -91.855 1.00 51.74 C +ATOM 4037 N LEU C 226 -20.972 16.041 -88.070 1.00 64.12 N +ATOM 4038 CA LEU C 226 -21.551 16.270 -86.750 1.00 62.51 C +ATOM 4039 C LEU C 226 -22.340 17.572 -86.713 1.00 63.23 C +ATOM 4040 O LEU C 226 -23.413 17.639 -86.101 1.00 55.47 O +ATOM 4041 CB LEU C 226 -20.444 16.285 -85.696 1.00 59.83 C +ATOM 4042 CG LEU C 226 -19.693 14.975 -85.453 1.00 57.53 C +ATOM 4043 CD1 LEU C 226 -18.588 15.188 -84.431 1.00 57.55 C +ATOM 4044 CD2 LEU C 226 -20.656 13.894 -84.986 1.00 55.89 C +ATOM 4045 N ARG C 227 -21.837 18.607 -87.395 1.00 66.86 N +ATOM 4046 CA ARG C 227 -22.501 19.907 -87.410 1.00 60.61 C +ATOM 4047 C ARG C 227 -23.844 19.831 -88.122 1.00 60.24 C +ATOM 4048 O ARG C 227 -24.803 20.505 -87.726 1.00 53.99 O +ATOM 4049 CB ARG C 227 -21.604 20.934 -88.099 1.00 58.09 C +ATOM 4050 CG ARG C 227 -20.246 21.115 -87.451 1.00 63.37 C +ATOM 4051 CD ARG C 227 -19.281 21.838 -88.382 1.00 70.39 C +ATOM 4052 NE ARG C 227 -17.967 22.022 -87.770 1.00 80.39 N +ATOM 4053 CZ ARG C 227 -16.905 22.507 -88.407 1.00 78.99 C +ATOM 4054 NH1 ARG C 227 -15.750 22.642 -87.768 1.00 84.75 N +ATOM 4055 NH2 ARG C 227 -16.997 22.846 -89.687 1.00 74.86 N +ATOM 4056 N ASP C 228 -23.927 19.017 -89.177 1.00 61.48 N +ATOM 4057 CA ASP C 228 -25.177 18.884 -89.916 1.00 63.32 C +ATOM 4058 C ASP C 228 -26.274 18.330 -89.021 1.00 65.07 C +ATOM 4059 O ASP C 228 -27.380 18.880 -88.959 1.00 67.26 O +ATOM 4060 CB ASP C 228 -24.981 17.982 -91.135 1.00 66.73 C +ATOM 4061 CG ASP C 228 -24.252 18.676 -92.266 1.00 67.81 C +ATOM 4062 OD1 ASP C 228 -24.181 19.922 -92.250 1.00 71.52 O +ATOM 4063 OD2 ASP C 228 -23.768 17.975 -93.181 1.00 64.50 O +ATOM 4064 N LEU C 229 -25.975 17.247 -88.302 1.00 59.39 N +ATOM 4065 CA LEU C 229 -26.975 16.635 -87.437 1.00 55.38 C +ATOM 4066 C LEU C 229 -27.454 17.605 -86.364 1.00 56.27 C +ATOM 4067 O LEU C 229 -28.631 17.573 -85.981 1.00 47.93 O +ATOM 4068 CB LEU C 229 -26.389 15.370 -86.808 1.00 59.27 C +ATOM 4069 CG LEU C 229 -25.694 14.430 -87.802 1.00 54.74 C +ATOM 4070 CD1 LEU C 229 -25.139 13.177 -87.133 1.00 44.68 C +ATOM 4071 CD2 LEU C 229 -26.657 14.052 -88.912 1.00 61.83 C +ATOM 4072 N LEU C 230 -26.578 18.517 -85.923 1.00 60.90 N +ATOM 4073 CA LEU C 230 -26.935 19.466 -84.870 1.00 57.46 C +ATOM 4074 C LEU C 230 -28.037 20.414 -85.318 1.00 53.86 C +ATOM 4075 O LEU C 230 -28.903 20.784 -84.517 1.00 52.92 O +ATOM 4076 CB LEU C 230 -25.704 20.277 -84.442 1.00 54.41 C +ATOM 4077 CG LEU C 230 -24.492 19.595 -83.800 1.00 59.95 C +ATOM 4078 CD1 LEU C 230 -23.332 20.558 -83.605 1.00 63.07 C +ATOM 4079 CD2 LEU C 230 -24.887 19.030 -82.470 1.00 56.43 C +ATOM 4080 N SER C 231 -28.018 20.823 -86.592 1.00 54.51 N +ATOM 4081 CA SER C 231 -28.813 21.960 -87.031 1.00 58.31 C +ATOM 4082 C SER C 231 -29.613 21.761 -88.313 1.00 53.50 C +ATOM 4083 O SER C 231 -30.457 22.613 -88.610 1.00 53.88 O +ATOM 4084 CB SER C 231 -27.909 23.192 -87.214 1.00 62.21 C +ATOM 4085 OG SER C 231 -26.816 22.898 -88.064 1.00 65.10 O +ATOM 4086 N GLN C 232 -29.385 20.700 -89.084 1.00 52.28 N +ATOM 4087 CA GLN C 232 -30.133 20.537 -90.327 1.00 54.26 C +ATOM 4088 C GLN C 232 -31.617 20.325 -90.041 1.00 49.73 C +ATOM 4089 O GLN C 232 -32.001 19.813 -88.988 1.00 52.66 O +ATOM 4090 CB GLN C 232 -29.575 19.375 -91.153 1.00 64.31 C +ATOM 4091 CG GLN C 232 -30.002 19.390 -92.629 1.00 70.93 C +ATOM 4092 CD GLN C 232 -29.212 20.368 -93.494 1.00 75.44 C +ATOM 4093 OE1 GLN C 232 -29.128 21.562 -93.196 1.00 78.97 O +ATOM 4094 NE2 GLN C 232 -28.660 19.866 -94.593 1.00 61.85 N +ATOM 4095 N LYS C 233 -32.453 20.709 -91.005 1.00 50.78 N +ATOM 4096 CA LYS C 233 -33.896 20.686 -90.810 1.00 53.47 C +ATOM 4097 C LYS C 233 -34.437 19.269 -90.911 1.00 57.25 C +ATOM 4098 O LYS C 233 -34.045 18.500 -91.792 1.00 60.10 O +ATOM 4099 CB LYS C 233 -34.592 21.581 -91.837 1.00 53.22 C +ATOM 4100 CG LYS C 233 -36.092 21.730 -91.610 1.00 59.07 C +ATOM 4101 CD LYS C 233 -36.699 22.794 -92.529 1.00 78.51 C +ATOM 4102 CE LYS C 233 -38.179 23.043 -92.204 1.00 83.40 C +ATOM 4103 NZ LYS C 233 -38.797 24.170 -92.978 1.00 62.55 N +ATOM 4104 N ILE C 234 -35.354 18.934 -90.009 1.00 59.14 N +ATOM 4105 CA ILE C 234 -35.951 17.603 -89.979 1.00 58.20 C +ATOM 4106 C ILE C 234 -37.035 17.536 -91.044 1.00 52.27 C +ATOM 4107 O ILE C 234 -37.973 18.338 -91.038 1.00 63.42 O +ATOM 4108 CB ILE C 234 -36.521 17.279 -88.591 1.00 58.62 C +ATOM 4109 CG1 ILE C 234 -35.415 17.305 -87.524 1.00 49.95 C +ATOM 4110 CG2 ILE C 234 -37.276 15.955 -88.622 1.00 50.07 C +ATOM 4111 CD1 ILE C 234 -34.294 16.309 -87.747 1.00 43.18 C +ATOM 4112 N SER C 235 -36.918 16.568 -91.952 1.00 51.72 N +ATOM 4113 CA SER C 235 -37.899 16.435 -93.022 1.00 52.01 C +ATOM 4114 C SER C 235 -38.999 15.439 -92.676 1.00 51.40 C +ATOM 4115 O SER C 235 -40.184 15.775 -92.761 1.00 49.52 O +ATOM 4116 CB SER C 235 -37.207 16.018 -94.320 1.00 51.26 C +ATOM 4117 OG SER C 235 -36.773 14.675 -94.240 1.00 50.40 O +ATOM 4118 N SER C 236 -38.629 14.217 -92.294 1.00 60.06 N +ATOM 4119 CA SER C 236 -39.604 13.194 -91.938 1.00 61.62 C +ATOM 4120 C SER C 236 -39.076 12.355 -90.783 1.00 60.00 C +ATOM 4121 O SER C 236 -37.874 12.097 -90.675 1.00 54.98 O +ATOM 4122 CB SER C 236 -39.945 12.285 -93.126 1.00 56.63 C +ATOM 4123 OG SER C 236 -40.892 11.299 -92.749 1.00 55.78 O +ATOM 4124 N VAL C 237 -39.997 11.907 -89.933 1.00 61.30 N +ATOM 4125 CA VAL C 237 -39.668 11.111 -88.759 1.00 56.36 C +ATOM 4126 C VAL C 237 -40.472 9.821 -88.812 1.00 55.35 C +ATOM 4127 O VAL C 237 -41.682 9.846 -89.068 1.00 47.54 O +ATOM 4128 CB VAL C 237 -39.948 11.874 -87.451 1.00 47.84 C +ATOM 4129 CG1 VAL C 237 -39.633 11.005 -86.261 1.00 49.90 C +ATOM 4130 CG2 VAL C 237 -39.118 13.141 -87.398 1.00 46.77 C +ATOM 4131 N GLY C 238 -39.795 8.704 -88.592 1.00 56.25 N +ATOM 4132 CA GLY C 238 -40.442 7.407 -88.601 1.00 55.55 C +ATOM 4133 C GLY C 238 -39.891 6.530 -87.500 1.00 53.97 C +ATOM 4134 O GLY C 238 -38.715 6.611 -87.139 1.00 53.09 O +ATOM 4135 N MET C 239 -40.765 5.688 -86.960 1.00 52.52 N +ATOM 4136 CA MET C 239 -40.400 4.787 -85.880 1.00 59.15 C +ATOM 4137 C MET C 239 -39.861 3.477 -86.448 1.00 61.42 C +ATOM 4138 O MET C 239 -40.430 2.917 -87.388 1.00 58.30 O +ATOM 4139 CB MET C 239 -41.613 4.528 -84.984 1.00 61.94 C +ATOM 4140 CG MET C 239 -41.307 3.715 -83.743 1.00 74.29 C +ATOM 4141 SD MET C 239 -42.786 3.133 -82.886 1.00 92.57 S +ATOM 4142 CE MET C 239 -43.571 4.666 -82.463 1.00 56.92 C +ATOM 4143 N LYS C 240 -38.763 2.992 -85.865 1.00 63.90 N +ATOM 4144 CA LYS C 240 -38.191 1.701 -86.235 1.00 66.53 C +ATOM 4145 C LYS C 240 -38.916 0.565 -85.520 1.00 75.03 C +ATOM 4146 O LYS C 240 -39.463 0.737 -84.427 1.00 86.41 O +ATOM 4147 CB LYS C 240 -36.699 1.650 -85.883 1.00 67.61 C +ATOM 4148 CG LYS C 240 -35.960 0.407 -86.384 1.00 72.45 C +ATOM 4149 CD LYS C 240 -34.532 0.345 -85.867 1.00 66.15 C +ATOM 4150 CE LYS C 240 -33.583 1.103 -86.791 1.00 54.96 C +ATOM 4151 NZ LYS C 240 -33.347 0.418 -88.098 1.00 42.38 N +ATOM 4152 N SER C 241 -38.921 -0.608 -86.146 1.00 69.01 N +ATOM 4153 CA SER C 241 -39.532 -1.781 -85.544 1.00 80.89 C +ATOM 4154 C SER C 241 -38.458 -2.813 -85.213 1.00 80.56 C +ATOM 4155 O SER C 241 -37.333 -2.762 -85.724 1.00 66.45 O +ATOM 4156 CB SER C 241 -40.597 -2.381 -86.475 1.00 81.46 C +ATOM 4157 OG SER C 241 -41.387 -3.357 -85.813 1.00 76.04 O +ATOM 4158 N GLY C 242 -38.813 -3.736 -84.313 1.00 79.72 N +ATOM 4159 CA GLY C 242 -38.002 -4.893 -83.982 1.00 79.02 C +ATOM 4160 C GLY C 242 -36.871 -4.672 -82.995 1.00 90.32 C +ATOM 4161 O GLY C 242 -36.216 -5.650 -82.607 1.00 89.77 O +ATOM 4162 N GLY C 243 -36.616 -3.434 -82.566 1.00 90.35 N +ATOM 4163 CA GLY C 243 -35.520 -3.153 -81.664 1.00 72.14 C +ATOM 4164 C GLY C 243 -35.885 -3.359 -80.205 1.00 72.42 C +ATOM 4165 O GLY C 243 -37.014 -3.695 -79.849 1.00 66.07 O +ATOM 4166 N THR C 244 -34.891 -3.131 -79.344 1.00 80.50 N +ATOM 4167 CA THR C 244 -35.106 -3.283 -77.907 1.00 72.16 C +ATOM 4168 C THR C 244 -35.970 -2.154 -77.353 1.00 67.96 C +ATOM 4169 O THR C 244 -37.066 -2.392 -76.835 1.00 66.19 O +ATOM 4170 CB THR C 244 -33.763 -3.345 -77.174 1.00 70.35 C +ATOM 4171 OG1 THR C 244 -32.691 -3.512 -78.117 1.00 65.46 O +ATOM 4172 CG2 THR C 244 -33.760 -4.511 -76.199 1.00 66.16 C +ATOM 4173 N GLN C 245 -35.500 -0.917 -77.475 1.00 69.23 N +ATOM 4174 CA GLN C 245 -36.170 0.276 -76.966 1.00 59.38 C +ATOM 4175 C GLN C 245 -36.547 1.181 -78.136 1.00 60.77 C +ATOM 4176 O GLN C 245 -36.378 0.826 -79.301 1.00 72.12 O +ATOM 4177 CB GLN C 245 -35.280 1.023 -75.966 1.00 56.22 C +ATOM 4178 CG GLN C 245 -35.450 0.596 -74.515 1.00 51.74 C +ATOM 4179 CD GLN C 245 -34.274 1.012 -73.647 1.00 52.60 C +ATOM 4180 OE1 GLN C 245 -33.822 2.156 -73.697 1.00 48.51 O +ATOM 4181 NE2 GLN C 245 -33.783 0.084 -72.835 1.00 54.94 N +ATOM 4182 N LEU C 246 -37.071 2.359 -77.811 1.00 55.18 N +ATOM 4183 CA LEU C 246 -37.543 3.292 -78.831 1.00 52.07 C +ATOM 4184 C LEU C 246 -36.367 3.970 -79.524 1.00 53.02 C +ATOM 4185 O LEU C 246 -35.506 4.561 -78.865 1.00 49.26 O +ATOM 4186 CB LEU C 246 -38.463 4.337 -78.212 1.00 49.17 C +ATOM 4187 CG LEU C 246 -39.038 5.346 -79.203 1.00 47.36 C +ATOM 4188 CD1 LEU C 246 -40.201 4.747 -79.982 1.00 49.68 C +ATOM 4189 CD2 LEU C 246 -39.459 6.599 -78.460 1.00 48.13 C +ATOM 4190 N LYS C 247 -36.319 3.862 -80.853 1.00 54.34 N +ATOM 4191 CA LYS C 247 -35.318 4.550 -81.664 1.00 54.09 C +ATOM 4192 C LYS C 247 -35.992 5.057 -82.931 1.00 57.28 C +ATOM 4193 O LYS C 247 -36.632 4.283 -83.649 1.00 63.95 O +ATOM 4194 CB LYS C 247 -34.123 3.632 -81.981 1.00 59.69 C +ATOM 4195 CG LYS C 247 -34.458 2.142 -82.098 1.00 69.32 C +ATOM 4196 CD LYS C 247 -33.218 1.249 -81.920 1.00 76.18 C +ATOM 4197 CE LYS C 247 -33.612 -0.216 -81.660 1.00 85.43 C +ATOM 4198 NZ LYS C 247 -32.469 -1.186 -81.525 1.00 86.43 N +ATOM 4199 N LEU C 248 -35.858 6.356 -83.195 1.00 51.08 N +ATOM 4200 CA LEU C 248 -36.537 7.015 -84.301 1.00 48.73 C +ATOM 4201 C LEU C 248 -35.580 7.299 -85.455 1.00 49.40 C +ATOM 4202 O LEU C 248 -34.397 7.583 -85.249 1.00 43.09 O +ATOM 4203 CB LEU C 248 -37.176 8.319 -83.821 1.00 45.44 C +ATOM 4204 CG LEU C 248 -38.661 8.229 -83.465 1.00 51.10 C +ATOM 4205 CD1 LEU C 248 -38.974 6.981 -82.647 1.00 58.10 C +ATOM 4206 CD2 LEU C 248 -39.105 9.485 -82.724 1.00 44.02 C +ATOM 4207 N ILE C 249 -36.116 7.251 -86.675 1.00 55.15 N +ATOM 4208 CA ILE C 249 -35.351 7.520 -87.892 1.00 56.57 C +ATOM 4209 C ILE C 249 -35.657 8.935 -88.360 1.00 51.38 C +ATOM 4210 O ILE C 249 -36.820 9.292 -88.588 1.00 47.87 O +ATOM 4211 CB ILE C 249 -35.653 6.500 -89.002 1.00 51.34 C +ATOM 4212 CG1 ILE C 249 -34.955 5.176 -88.711 1.00 58.56 C +ATOM 4213 CG2 ILE C 249 -35.171 7.018 -90.347 1.00 49.42 C +ATOM 4214 CD1 ILE C 249 -35.742 4.253 -87.842 1.00 62.02 C +ATOM 4215 N MET C 250 -34.607 9.732 -88.512 1.00 48.31 N +ATOM 4216 CA MET C 250 -34.707 11.102 -88.980 1.00 50.96 C +ATOM 4217 C MET C 250 -34.225 11.173 -90.421 1.00 56.63 C +ATOM 4218 O MET C 250 -33.273 10.487 -90.800 1.00 48.73 O +ATOM 4219 CB MET C 250 -33.871 12.038 -88.102 1.00 51.14 C +ATOM 4220 CG MET C 250 -34.164 11.929 -86.613 1.00 46.21 C +ATOM 4221 SD MET C 250 -35.417 13.068 -86.027 1.00 39.27 S +ATOM 4222 CE MET C 250 -35.778 12.414 -84.410 1.00 39.08 C +ATOM 4223 N SER C 251 -34.892 11.997 -91.221 1.00 66.27 N +ATOM 4224 CA SER C 251 -34.469 12.306 -92.577 1.00 56.10 C +ATOM 4225 C SER C 251 -34.308 13.813 -92.697 1.00 53.59 C +ATOM 4226 O SER C 251 -35.097 14.576 -92.131 1.00 56.54 O +ATOM 4227 CB SER C 251 -35.479 11.783 -93.598 1.00 55.35 C +ATOM 4228 OG SER C 251 -35.517 10.366 -93.583 1.00 53.94 O +ATOM 4229 N PHE C 252 -33.297 14.247 -93.432 1.00 53.87 N +ATOM 4230 CA PHE C 252 -32.947 15.656 -93.445 1.00 58.44 C +ATOM 4231 C PHE C 252 -33.203 16.283 -94.807 1.00 59.54 C +ATOM 4232 O PHE C 252 -33.555 15.620 -95.787 1.00 54.80 O +ATOM 4233 CB PHE C 252 -31.485 15.852 -93.041 1.00 58.59 C +ATOM 4234 CG PHE C 252 -31.187 15.395 -91.655 1.00 52.73 C +ATOM 4235 CD1 PHE C 252 -31.426 16.223 -90.577 1.00 56.03 C +ATOM 4236 CD2 PHE C 252 -30.670 14.137 -91.428 1.00 54.77 C +ATOM 4237 CE1 PHE C 252 -31.152 15.807 -89.295 1.00 67.63 C +ATOM 4238 CE2 PHE C 252 -30.393 13.711 -90.150 1.00 60.98 C +ATOM 4239 CZ PHE C 252 -30.633 14.547 -89.078 1.00 70.07 C +ATOM 4240 N GLN C 253 -33.003 17.600 -94.841 1.00 61.93 N +ATOM 4241 CA GLN C 253 -33.222 18.362 -96.059 1.00 67.98 C +ATOM 4242 C GLN C 253 -32.265 17.944 -97.166 1.00 67.91 C +ATOM 4243 O GLN C 253 -32.599 18.080 -98.348 1.00 67.82 O +ATOM 4244 CB GLN C 253 -33.069 19.851 -95.740 1.00 65.29 C +ATOM 4245 CG GLN C 253 -33.609 20.799 -96.778 1.00 66.29 C +ATOM 4246 CD GLN C 253 -33.464 22.238 -96.341 1.00 77.25 C +ATOM 4247 OE1 GLN C 253 -34.454 22.925 -96.086 1.00 85.12 O +ATOM 4248 NE2 GLN C 253 -32.223 22.700 -96.231 1.00 78.80 N +ATOM 4249 N ASN C 254 -31.105 17.392 -96.809 1.00 63.53 N +ATOM 4250 CA ASN C 254 -30.121 16.929 -97.778 1.00 57.90 C +ATOM 4251 C ASN C 254 -30.168 15.419 -97.957 1.00 52.00 C +ATOM 4252 O ASN C 254 -29.130 14.785 -98.173 1.00 49.51 O +ATOM 4253 CB ASN C 254 -28.719 17.385 -97.379 1.00 57.73 C +ATOM 4254 CG ASN C 254 -28.383 17.043 -95.953 1.00 50.84 C +ATOM 4255 OD1 ASN C 254 -28.854 17.692 -95.022 1.00 56.41 O +ATOM 4256 ND2 ASN C 254 -27.562 16.025 -95.768 1.00 50.00 N +ATOM 4257 N TYR C 255 -31.351 14.826 -97.795 1.00 54.45 N +ATOM 4258 CA TYR C 255 -31.596 13.418 -98.099 1.00 64.87 C +ATOM 4259 C TYR C 255 -30.792 12.467 -97.214 1.00 65.08 C +ATOM 4260 O TYR C 255 -30.951 11.242 -97.305 1.00 60.66 O +ATOM 4261 CB TYR C 255 -31.320 13.146 -99.583 1.00 55.20 C +ATOM 4262 CG TYR C 255 -32.227 13.930-100.510 1.00 50.90 C +ATOM 4263 CD1 TYR C 255 -31.914 15.230-100.878 1.00 57.79 C +ATOM 4264 CD2 TYR C 255 -33.393 13.367-101.019 1.00 49.14 C +ATOM 4265 CE1 TYR C 255 -32.738 15.954-101.723 1.00 64.19 C +ATOM 4266 CE2 TYR C 255 -34.222 14.082-101.865 1.00 55.90 C +ATOM 4267 CZ TYR C 255 -33.890 15.375-102.215 1.00 64.53 C +ATOM 4268 OH TYR C 255 -34.710 16.096-103.059 1.00 64.51 O +ATOM 4269 N GLY C 256 -29.930 13.008 -96.358 1.00 60.10 N +ATOM 4270 CA GLY C 256 -29.262 12.178 -95.382 1.00 56.77 C +ATOM 4271 C GLY C 256 -30.200 11.763 -94.268 1.00 61.22 C +ATOM 4272 O GLY C 256 -31.217 12.402 -93.997 1.00 64.27 O +ATOM 4273 N GLN C 257 -29.851 10.662 -93.608 1.00 59.09 N +ATOM 4274 CA GLN C 257 -30.658 10.158 -92.509 1.00 52.10 C +ATOM 4275 C GLN C 257 -29.746 9.735 -91.365 1.00 43.28 C +ATOM 4276 O GLN C 257 -28.524 9.631 -91.513 1.00 38.00 O +ATOM 4277 CB GLN C 257 -31.574 9.012 -92.970 1.00 48.59 C +ATOM 4278 CG GLN C 257 -31.070 8.239 -94.176 1.00 52.51 C +ATOM 4279 CD GLN C 257 -32.121 7.307 -94.745 1.00 54.74 C +ATOM 4280 OE1 GLN C 257 -33.297 7.666 -94.847 1.00 47.38 O +ATOM 4281 NE2 GLN C 257 -31.707 6.090 -95.095 1.00 54.26 N +ATOM 4282 N ALA C 258 -30.361 9.511 -90.205 1.00 42.68 N +ATOM 4283 CA ALA C 258 -29.638 9.179 -88.987 1.00 38.00 C +ATOM 4284 C ALA C 258 -30.595 8.511 -88.011 1.00 38.00 C +ATOM 4285 O ALA C 258 -31.815 8.664 -88.108 1.00 38.00 O +ATOM 4286 CB ALA C 258 -29.004 10.424 -88.360 1.00 38.00 C +ATOM 4287 N LEU C 259 -30.024 7.746 -87.085 1.00 38.00 N +ATOM 4288 CA LEU C 259 -30.779 7.158 -85.989 1.00 38.00 C +ATOM 4289 C LEU C 259 -30.867 8.136 -84.831 1.00 38.00 C +ATOM 4290 O LEU C 259 -29.965 8.943 -84.600 1.00 38.00 O +ATOM 4291 CB LEU C 259 -30.135 5.860 -85.504 1.00 40.63 C +ATOM 4292 CG LEU C 259 -31.082 4.683 -85.281 1.00 42.26 C +ATOM 4293 CD1 LEU C 259 -31.579 4.161 -86.625 1.00 53.34 C +ATOM 4294 CD2 LEU C 259 -30.411 3.583 -84.479 1.00 38.00 C +ATOM 4295 N PHE C 260 -31.936 8.012 -84.058 1.00 38.00 N +ATOM 4296 CA PHE C 260 -32.209 8.965 -82.995 1.00 44.05 C +ATOM 4297 C PHE C 260 -32.608 8.223 -81.736 1.00 51.91 C +ATOM 4298 O PHE C 260 -33.620 7.516 -81.723 1.00 55.33 O +ATOM 4299 CB PHE C 260 -33.309 9.942 -83.408 1.00 46.88 C +ATOM 4300 CG PHE C 260 -33.766 10.827 -82.298 1.00 48.60 C +ATOM 4301 CD1 PHE C 260 -33.057 11.967 -81.975 1.00 48.20 C +ATOM 4302 CD2 PHE C 260 -34.935 10.542 -81.604 1.00 49.09 C +ATOM 4303 CE1 PHE C 260 -33.478 12.791 -80.953 1.00 53.32 C +ATOM 4304 CE2 PHE C 260 -35.365 11.365 -80.586 1.00 50.46 C +ATOM 4305 CZ PHE C 260 -34.635 12.491 -80.258 1.00 52.41 C +ATOM 4306 N LYS C 261 -31.822 8.397 -80.680 1.00 44.90 N +ATOM 4307 CA LYS C 261 -32.173 7.862 -79.380 1.00 44.61 C +ATOM 4308 C LYS C 261 -32.424 9.014 -78.420 1.00 45.07 C +ATOM 4309 O LYS C 261 -31.550 9.879 -78.258 1.00 44.93 O +ATOM 4310 CB LYS C 261 -31.073 6.940 -78.852 1.00 50.62 C +ATOM 4311 CG LYS C 261 -30.891 5.661 -79.672 1.00 51.27 C +ATOM 4312 CD LYS C 261 -29.971 4.675 -78.959 1.00 59.97 C +ATOM 4313 CE LYS C 261 -29.909 3.338 -79.694 1.00 74.88 C +ATOM 4314 NZ LYS C 261 -28.978 2.363 -79.044 1.00 72.99 N +ATOM 4315 N PRO C 262 -33.601 9.069 -77.768 1.00 46.10 N +ATOM 4316 CA PRO C 262 -33.934 10.222 -76.922 1.00 48.98 C +ATOM 4317 C PRO C 262 -33.197 10.229 -75.592 1.00 57.97 C +ATOM 4318 O PRO C 262 -32.267 9.447 -75.377 1.00 60.46 O +ATOM 4319 CB PRO C 262 -35.447 10.079 -76.706 1.00 42.74 C +ATOM 4320 CG PRO C 262 -35.903 8.992 -77.629 1.00 38.00 C +ATOM 4321 CD PRO C 262 -34.722 8.123 -77.856 1.00 40.40 C +ATOM 4322 N MET C 263 -33.584 11.158 -74.714 1.00 56.02 N +ATOM 4323 CA MET C 263 -32.903 11.313 -73.432 1.00 57.42 C +ATOM 4324 C MET C 263 -33.094 10.086 -72.550 1.00 59.80 C +ATOM 4325 O MET C 263 -32.121 9.455 -72.117 1.00 59.71 O +ATOM 4326 CB MET C 263 -33.389 12.571 -72.717 1.00 55.47 C +ATOM 4327 CG MET C 263 -32.711 12.762 -71.379 1.00 59.25 C +ATOM 4328 SD MET C 263 -32.316 14.485 -71.055 1.00 65.02 S +ATOM 4329 CE MET C 263 -30.932 14.313 -69.919 1.00 53.98 C +ATOM 4330 N LYS C 264 -34.347 9.790 -72.207 1.00 61.45 N +ATOM 4331 CA LYS C 264 -34.751 8.615 -71.438 1.00 67.17 C +ATOM 4332 C LYS C 264 -34.341 8.717 -69.966 1.00 63.14 C +ATOM 4333 O LYS C 264 -35.128 8.358 -69.083 1.00 54.08 O +ATOM 4334 CB LYS C 264 -34.201 7.337 -72.085 1.00 62.79 C +ATOM 4335 CG LYS C 264 -35.021 6.102 -71.760 1.00 64.11 C +ATOM 4336 CD LYS C 264 -36.401 6.195 -72.415 1.00 69.70 C +ATOM 4337 CE LYS C 264 -37.510 5.561 -71.560 1.00 70.68 C +ATOM 4338 NZ LYS C 264 -37.765 6.252 -70.255 1.00 69.22 N +ATOM 4339 N GLN C 265 -33.136 9.209 -69.674 1.00 67.03 N +ATOM 4340 CA GLN C 265 -32.733 9.374 -68.282 1.00 70.27 C +ATOM 4341 C GLN C 265 -31.730 10.519 -68.154 1.00 74.46 C +ATOM 4342 O GLN C 265 -31.059 10.900 -69.119 1.00 74.51 O +ATOM 4343 CB GLN C 265 -32.150 8.079 -67.697 1.00 66.81 C +ATOM 4344 CG GLN C 265 -33.055 7.403 -66.659 1.00 67.80 C +ATOM 4345 CD GLN C 265 -33.600 8.372 -65.612 1.00 86.09 C +ATOM 4346 OE1 GLN C 265 -32.933 9.334 -65.226 1.00 94.40 O +ATOM 4347 NE2 GLN C 265 -34.818 8.109 -65.140 1.00 72.66 N +ATOM 4348 N THR C 266 -31.624 11.047 -66.928 1.00 72.45 N +ATOM 4349 CA THR C 266 -30.829 12.228 -66.608 1.00 67.52 C +ATOM 4350 C THR C 266 -29.346 11.877 -66.471 1.00 67.05 C +ATOM 4351 O THR C 266 -28.931 10.729 -66.649 1.00 79.60 O +ATOM 4352 CB THR C 266 -31.328 12.858 -65.312 1.00 66.17 C +ATOM 4353 OG1 THR C 266 -30.924 12.041 -64.208 1.00 62.83 O +ATOM 4354 CG2 THR C 266 -32.847 12.940 -65.325 1.00 57.50 C +ATOM 4355 N ARG C 267 -28.534 12.872 -66.109 1.00 59.16 N +ATOM 4356 CA ARG C 267 -27.089 12.672 -66.037 1.00 68.83 C +ATOM 4357 C ARG C 267 -26.640 12.118 -64.693 1.00 75.82 C +ATOM 4358 O ARG C 267 -25.847 11.173 -64.638 1.00 75.89 O +ATOM 4359 CB ARG C 267 -26.338 13.981 -66.316 1.00 70.33 C +ATOM 4360 CG ARG C 267 -25.831 14.147 -67.746 1.00 67.51 C +ATOM 4361 CD ARG C 267 -26.952 14.084 -68.773 1.00 66.06 C +ATOM 4362 NE ARG C 267 -26.488 14.451 -70.108 1.00 58.61 N +ATOM 4363 CZ ARG C 267 -26.507 15.687 -70.593 1.00 60.95 C +ATOM 4364 NH1 ARG C 267 -26.963 16.687 -69.853 1.00 72.50 N +ATOM 4365 NH2 ARG C 267 -26.068 15.926 -71.818 1.00 53.87 N +ATOM 4366 N GLU C 268 -27.128 12.698 -63.604 1.00 85.89 N +ATOM 4367 CA GLU C 268 -26.675 12.303 -62.279 1.00 90.04 C +ATOM 4368 C GLU C 268 -27.291 10.991 -61.813 1.00 83.90 C +ATOM 4369 O GLU C 268 -27.040 10.580 -60.673 1.00 87.65 O +ATOM 4370 CB GLU C 268 -26.971 13.418 -61.267 1.00 92.76 C +ATOM 4371 CG GLU C 268 -26.270 14.749 -61.562 1.00 82.82 C +ATOM 4372 CD GLU C 268 -27.028 15.625 -62.550 1.00 95.87 C +ATOM 4373 OE1 GLU C 268 -28.160 15.255 -62.941 1.00 97.06 O +ATOM 4374 OE2 GLU C 268 -26.487 16.684 -62.936 1.00 91.09 O +ATOM 4375 N GLN C 269 -28.070 10.323 -62.660 1.00 76.93 N +ATOM 4376 CA GLN C 269 -28.722 9.080 -62.282 1.00 79.74 C +ATOM 4377 C GLN C 269 -27.836 7.883 -62.607 1.00 82.13 C +ATOM 4378 O GLN C 269 -27.075 7.889 -63.579 1.00 82.41 O +ATOM 4379 CB GLN C 269 -30.071 8.929 -62.988 1.00 68.57 C +ATOM 4380 CG GLN C 269 -31.246 9.446 -62.183 1.00 73.77 C +ATOM 4381 CD GLN C 269 -32.527 8.693 -62.493 1.00 83.51 C +ATOM 4382 OE1 GLN C 269 -32.492 7.510 -62.831 1.00 88.27 O +ATOM 4383 NE2 GLN C 269 -33.664 9.375 -62.383 1.00 88.82 N +ATOM 4384 N GLU C 270 -27.941 6.853 -61.773 1.00 79.54 N +ATOM 4385 CA GLU C 270 -27.224 5.602 -61.959 1.00 68.92 C +ATOM 4386 C GLU C 270 -28.217 4.473 -62.200 1.00 71.13 C +ATOM 4387 O GLU C 270 -29.368 4.533 -61.753 1.00 64.46 O +ATOM 4388 CB GLU C 270 -26.344 5.273 -60.750 1.00 66.44 C +ATOM 4389 CG GLU C 270 -25.018 6.002 -60.744 1.00 65.71 C +ATOM 4390 CD GLU C 270 -24.007 5.361 -59.816 1.00 74.29 C +ATOM 4391 OE1 GLU C 270 -23.751 4.143 -59.946 1.00 78.43 O +ATOM 4392 OE2 GLU C 270 -23.494 6.072 -58.929 1.00 76.86 O +ATOM 4393 N THR C 271 -27.771 3.459 -62.936 1.00 68.79 N +ATOM 4394 CA THR C 271 -28.587 2.268 -63.130 1.00 64.25 C +ATOM 4395 C THR C 271 -28.826 1.598 -61.781 1.00 62.97 C +ATOM 4396 O THR C 271 -27.862 1.352 -61.041 1.00 60.19 O +ATOM 4397 CB THR C 271 -27.901 1.284 -64.079 1.00 63.10 C +ATOM 4398 OG1 THR C 271 -27.718 1.896 -65.362 1.00 62.97 O +ATOM 4399 CG2 THR C 271 -28.748 0.033 -64.249 1.00 64.97 C +ATOM 4400 N PRO C 272 -30.073 1.285 -61.428 1.00 54.25 N +ATOM 4401 CA PRO C 272 -30.342 0.627 -60.148 1.00 52.81 C +ATOM 4402 C PRO C 272 -29.504 -0.628 -60.013 1.00 63.53 C +ATOM 4403 O PRO C 272 -29.307 -1.358 -60.996 1.00 70.93 O +ATOM 4404 CB PRO C 272 -31.837 0.288 -60.233 1.00 45.60 C +ATOM 4405 CG PRO C 272 -32.385 1.285 -61.171 1.00 47.54 C +ATOM 4406 CD PRO C 272 -31.309 1.553 -62.180 1.00 46.97 C +ATOM 4407 N PRO C 273 -28.975 -0.907 -58.822 1.00 58.03 N +ATOM 4408 CA PRO C 273 -28.118 -2.092 -58.670 1.00 58.84 C +ATOM 4409 C PRO C 273 -28.851 -3.392 -58.933 1.00 55.72 C +ATOM 4410 O PRO C 273 -28.211 -4.384 -59.301 1.00 51.72 O +ATOM 4411 CB PRO C 273 -27.637 -1.995 -57.216 1.00 58.79 C +ATOM 4412 CG PRO C 273 -27.860 -0.560 -56.828 1.00 59.35 C +ATOM 4413 CD PRO C 273 -29.077 -0.130 -57.578 1.00 52.16 C +ATOM 4414 N ASP C 274 -30.174 -3.409 -58.789 1.00 52.84 N +ATOM 4415 CA ASP C 274 -30.977 -4.609 -58.969 1.00 54.93 C +ATOM 4416 C ASP C 274 -31.437 -4.796 -60.414 1.00 52.11 C +ATOM 4417 O ASP C 274 -32.224 -5.708 -60.692 1.00 47.25 O +ATOM 4418 CB ASP C 274 -32.180 -4.571 -58.018 1.00 58.21 C +ATOM 4419 CG ASP C 274 -31.789 -4.200 -56.590 1.00 60.07 C +ATOM 4420 OD1 ASP C 274 -31.538 -3.002 -56.338 1.00 68.16 O +ATOM 4421 OD2 ASP C 274 -31.740 -5.095 -55.717 1.00 51.59 O +ATOM 4422 N PHE C 275 -30.974 -3.951 -61.332 1.00 54.97 N +ATOM 4423 CA PHE C 275 -31.321 -4.068 -62.742 1.00 55.54 C +ATOM 4424 C PHE C 275 -30.350 -5.013 -63.438 1.00 53.34 C +ATOM 4425 O PHE C 275 -29.131 -4.906 -63.260 1.00 49.11 O +ATOM 4426 CB PHE C 275 -31.303 -2.705 -63.439 1.00 55.87 C +ATOM 4427 CG PHE C 275 -32.640 -2.011 -63.473 1.00 57.87 C +ATOM 4428 CD1 PHE C 275 -33.730 -2.529 -62.791 1.00 59.28 C +ATOM 4429 CD2 PHE C 275 -32.812 -0.854 -64.219 1.00 55.01 C +ATOM 4430 CE1 PHE C 275 -34.962 -1.892 -62.834 1.00 60.66 C +ATOM 4431 CE2 PHE C 275 -34.040 -0.215 -64.269 1.00 57.62 C +ATOM 4432 CZ PHE C 275 -35.115 -0.734 -63.576 1.00 59.84 C +ATOM 4433 N PHE C 276 -30.896 -5.957 -64.198 1.00 49.94 N +ATOM 4434 CA PHE C 276 -30.061 -6.792 -65.041 1.00 51.49 C +ATOM 4435 C PHE C 276 -29.485 -5.970 -66.191 1.00 53.47 C +ATOM 4436 O PHE C 276 -29.991 -4.899 -66.537 1.00 54.93 O +ATOM 4437 CB PHE C 276 -30.859 -7.968 -65.599 1.00 51.81 C +ATOM 4438 CG PHE C 276 -31.062 -9.086 -64.621 1.00 55.34 C +ATOM 4439 CD1 PHE C 276 -30.014 -9.929 -64.295 1.00 56.43 C +ATOM 4440 CD2 PHE C 276 -32.311 -9.333 -64.073 1.00 56.22 C +ATOM 4441 CE1 PHE C 276 -30.196 -10.971 -63.409 1.00 63.41 C +ATOM 4442 CE2 PHE C 276 -32.501 -10.381 -63.188 1.00 59.98 C +ATOM 4443 CZ PHE C 276 -31.441 -11.201 -62.857 1.00 60.94 C +ATOM 4444 N TYR C 277 -28.434 -6.509 -66.818 1.00 54.91 N +ATOM 4445 CA TYR C 277 -27.852 -5.834 -67.974 1.00 48.23 C +ATOM 4446 C TYR C 277 -28.875 -5.677 -69.091 1.00 43.31 C +ATOM 4447 O TYR C 277 -28.808 -4.713 -69.863 1.00 40.82 O +ATOM 4448 CB TYR C 277 -26.623 -6.600 -68.479 1.00 49.79 C +ATOM 4449 CG TYR C 277 -26.762 -8.111 -68.421 1.00 63.88 C +ATOM 4450 CD1 TYR C 277 -27.330 -8.825 -69.472 1.00 55.86 C +ATOM 4451 CD2 TYR C 277 -26.335 -8.823 -67.305 1.00 76.45 C +ATOM 4452 CE1 TYR C 277 -27.467 -10.206 -69.409 1.00 57.98 C +ATOM 4453 CE2 TYR C 277 -26.466 -10.207 -67.236 1.00 78.69 C +ATOM 4454 CZ TYR C 277 -27.031 -10.892 -68.292 1.00 71.29 C +ATOM 4455 OH TYR C 277 -27.162 -12.265 -68.223 1.00 74.61 O +ATOM 4456 N PHE C 278 -29.843 -6.585 -69.176 1.00 47.35 N +ATOM 4457 CA PHE C 278 -30.887 -6.485 -70.184 1.00 49.08 C +ATOM 4458 C PHE C 278 -32.093 -5.690 -69.704 1.00 44.33 C +ATOM 4459 O PHE C 278 -33.142 -5.731 -70.350 1.00 44.38 O +ATOM 4460 CB PHE C 278 -31.315 -7.878 -70.670 1.00 52.82 C +ATOM 4461 CG PHE C 278 -31.794 -8.809 -69.584 1.00 48.39 C +ATOM 4462 CD1 PHE C 278 -33.129 -8.833 -69.210 1.00 47.57 C +ATOM 4463 CD2 PHE C 278 -30.915 -9.688 -68.967 1.00 46.44 C +ATOM 4464 CE1 PHE C 278 -33.577 -9.703 -68.227 1.00 44.75 C +ATOM 4465 CE2 PHE C 278 -31.356 -10.555 -67.986 1.00 48.61 C +ATOM 4466 CZ PHE C 278 -32.689 -10.562 -67.615 1.00 48.88 C +ATOM 4467 N SER C 279 -31.972 -4.982 -68.584 1.00 46.01 N +ATOM 4468 CA SER C 279 -33.006 -4.062 -68.138 1.00 50.52 C +ATOM 4469 C SER C 279 -32.517 -2.622 -68.111 1.00 49.48 C +ATOM 4470 O SER C 279 -33.319 -1.713 -67.860 1.00 44.83 O +ATOM 4471 CB SER C 279 -33.525 -4.461 -66.750 1.00 55.67 C +ATOM 4472 OG SER C 279 -34.104 -5.755 -66.770 1.00 56.28 O +ATOM 4473 N ASP C 280 -31.237 -2.389 -68.393 1.00 49.74 N +ATOM 4474 CA ASP C 280 -30.663 -1.053 -68.337 1.00 50.60 C +ATOM 4475 C ASP C 280 -31.258 -0.164 -69.424 1.00 54.36 C +ATOM 4476 O ASP C 280 -31.743 -0.637 -70.454 1.00 53.92 O +ATOM 4477 CB ASP C 280 -29.140 -1.132 -68.486 1.00 48.96 C +ATOM 4478 CG ASP C 280 -28.422 0.058 -67.870 1.00 58.60 C +ATOM 4479 OD1 ASP C 280 -28.967 1.180 -67.933 1.00 67.27 O +ATOM 4480 OD2 ASP C 280 -27.319 -0.133 -67.308 1.00 51.05 O +ATOM 4481 N PHE C 281 -31.241 1.139 -69.171 1.00 57.52 N +ATOM 4482 CA PHE C 281 -31.764 2.092 -70.133 1.00 55.10 C +ATOM 4483 C PHE C 281 -30.751 2.354 -71.236 1.00 61.22 C +ATOM 4484 O PHE C 281 -29.538 2.314 -71.013 1.00 63.29 O +ATOM 4485 CB PHE C 281 -32.125 3.406 -69.446 1.00 55.20 C +ATOM 4486 CG PHE C 281 -33.278 3.292 -68.498 1.00 57.58 C +ATOM 4487 CD1 PHE C 281 -34.546 2.991 -68.971 1.00 54.66 C +ATOM 4488 CD2 PHE C 281 -33.104 3.502 -67.141 1.00 50.24 C +ATOM 4489 CE1 PHE C 281 -35.614 2.891 -68.110 1.00 50.41 C +ATOM 4490 CE2 PHE C 281 -34.172 3.400 -66.276 1.00 51.92 C +ATOM 4491 CZ PHE C 281 -35.427 3.093 -66.763 1.00 54.82 C +ATOM 4492 N GLU C 282 -31.262 2.622 -72.438 1.00 59.14 N +ATOM 4493 CA GLU C 282 -30.443 3.130 -73.534 1.00 53.58 C +ATOM 4494 C GLU C 282 -30.544 4.648 -73.521 1.00 52.53 C +ATOM 4495 O GLU C 282 -31.621 5.207 -73.750 1.00 55.27 O +ATOM 4496 CB GLU C 282 -30.883 2.554 -74.876 1.00 47.50 C +ATOM 4497 CG GLU C 282 -30.528 1.096 -75.064 1.00 51.90 C +ATOM 4498 CD GLU C 282 -30.650 0.653 -76.508 1.00 64.71 C +ATOM 4499 OE1 GLU C 282 -31.617 1.074 -77.177 1.00 71.56 O +ATOM 4500 OE2 GLU C 282 -29.776 -0.111 -76.975 1.00 71.03 O +ATOM 4501 N ARG C 283 -29.427 5.315 -73.237 1.00 46.66 N +ATOM 4502 CA ARG C 283 -29.411 6.758 -73.060 1.00 52.83 C +ATOM 4503 C ARG C 283 -28.538 7.419 -74.120 1.00 61.04 C +ATOM 4504 O ARG C 283 -27.476 6.901 -74.489 1.00 56.80 O +ATOM 4505 CB ARG C 283 -28.916 7.136 -71.659 1.00 54.89 C +ATOM 4506 CG ARG C 283 -27.459 6.795 -71.381 1.00 61.58 C +ATOM 4507 CD ARG C 283 -27.277 6.303 -69.955 1.00 64.12 C +ATOM 4508 NE ARG C 283 -27.121 4.854 -69.888 1.00 58.43 N +ATOM 4509 CZ ARG C 283 -27.358 4.131 -68.801 1.00 56.72 C +ATOM 4510 NH1 ARG C 283 -27.780 4.722 -67.694 1.00 66.95 N +ATOM 4511 NH2 ARG C 283 -27.183 2.819 -68.823 1.00 55.91 N +ATOM 4512 N HIS C 284 -28.998 8.588 -74.580 1.00 65.28 N +ATOM 4513 CA HIS C 284 -28.274 9.378 -75.573 1.00 62.69 C +ATOM 4514 C HIS C 284 -26.886 9.781 -75.085 1.00 54.25 C +ATOM 4515 O HIS C 284 -25.975 9.975 -75.899 1.00 47.89 O +ATOM 4516 CB HIS C 284 -29.103 10.612 -75.936 1.00 57.57 C +ATOM 4517 CG HIS C 284 -29.324 11.550 -74.792 1.00 53.02 C +ATOM 4518 ND1 HIS C 284 -29.548 11.116 -73.503 1.00 56.09 N +ATOM 4519 CD2 HIS C 284 -29.337 12.902 -74.741 1.00 56.99 C +ATOM 4520 CE1 HIS C 284 -29.691 12.160 -72.707 1.00 62.32 C +ATOM 4521 NE2 HIS C 284 -29.568 13.256 -73.434 1.00 64.21 N +ATOM 4522 N ASN C 285 -26.717 9.933 -73.769 1.00 54.12 N +ATOM 4523 CA ASN C 285 -25.407 10.218 -73.196 1.00 52.06 C +ATOM 4524 C ASN C 285 -24.370 9.231 -73.707 1.00 57.62 C +ATOM 4525 O ASN C 285 -23.299 9.618 -74.188 1.00 54.63 O +ATOM 4526 CB ASN C 285 -25.477 10.129 -71.669 1.00 54.81 C +ATOM 4527 CG ASN C 285 -26.698 10.809 -71.100 1.00 63.74 C +ATOM 4528 OD1 ASN C 285 -26.994 11.954 -71.435 1.00 77.45 O +ATOM 4529 ND2 ASN C 285 -27.428 10.099 -70.240 1.00 56.73 N +ATOM 4530 N ALA C 286 -24.696 7.938 -73.628 1.00 58.55 N +ATOM 4531 CA ALA C 286 -23.730 6.900 -73.959 1.00 57.06 C +ATOM 4532 C ALA C 286 -23.373 6.924 -75.438 1.00 55.17 C +ATOM 4533 O ALA C 286 -22.192 6.829 -75.796 1.00 49.49 O +ATOM 4534 CB ALA C 286 -24.284 5.533 -73.560 1.00 55.84 C +ATOM 4535 N GLU C 287 -24.376 7.094 -76.306 1.00 54.66 N +ATOM 4536 CA GLU C 287 -24.135 7.067 -77.747 1.00 55.84 C +ATOM 4537 C GLU C 287 -23.116 8.122 -78.150 1.00 53.06 C +ATOM 4538 O GLU C 287 -22.129 7.822 -78.831 1.00 48.23 O +ATOM 4539 CB GLU C 287 -25.452 7.278 -78.494 1.00 59.58 C +ATOM 4540 CG GLU C 287 -26.451 6.143 -78.340 1.00 59.08 C +ATOM 4541 CD GLU C 287 -26.086 4.922 -79.166 1.00 60.69 C +ATOM 4542 OE1 GLU C 287 -25.158 5.011 -80.001 1.00 57.26 O +ATOM 4543 OE2 GLU C 287 -26.728 3.868 -78.977 1.00 64.34 O +ATOM 4544 N ILE C 288 -23.330 9.362 -77.709 1.00 55.82 N +ATOM 4545 CA ILE C 288 -22.412 10.450 -78.025 1.00 48.98 C +ATOM 4546 C ILE C 288 -21.062 10.217 -77.363 1.00 50.21 C +ATOM 4547 O ILE C 288 -20.008 10.413 -77.980 1.00 49.44 O +ATOM 4548 CB ILE C 288 -23.021 11.789 -77.582 1.00 47.36 C +ATOM 4549 CG1 ILE C 288 -24.465 11.900 -78.065 1.00 49.33 C +ATOM 4550 CG2 ILE C 288 -22.190 12.939 -78.111 1.00 50.12 C +ATOM 4551 CD1 ILE C 288 -25.223 13.048 -77.442 1.00 46.52 C +ATOM 4552 N ALA C 289 -21.072 9.796 -76.097 1.00 48.55 N +ATOM 4553 CA ALA C 289 -19.820 9.574 -75.388 1.00 50.26 C +ATOM 4554 C ALA C 289 -19.015 8.461 -76.035 1.00 48.39 C +ATOM 4555 O ALA C 289 -17.783 8.536 -76.111 1.00 48.27 O +ATOM 4556 CB ALA C 289 -20.103 9.239 -73.925 1.00 53.36 C +ATOM 4557 N ALA C 290 -19.701 7.434 -76.538 1.00 47.32 N +ATOM 4558 CA ALA C 290 -19.001 6.314 -77.151 1.00 51.34 C +ATOM 4559 C ALA C 290 -18.220 6.758 -78.376 1.00 50.91 C +ATOM 4560 O ALA C 290 -17.098 6.293 -78.609 1.00 49.36 O +ATOM 4561 CB ALA C 290 -19.995 5.217 -77.528 1.00 54.89 C +ATOM 4562 N PHE C 291 -18.782 7.687 -79.150 1.00 53.26 N +ATOM 4563 CA PHE C 291 -18.123 8.113 -80.377 1.00 54.56 C +ATOM 4564 C PHE C 291 -16.800 8.804 -80.075 1.00 55.17 C +ATOM 4565 O PHE C 291 -15.769 8.481 -80.678 1.00 52.19 O +ATOM 4566 CB PHE C 291 -19.047 9.027 -81.181 1.00 50.36 C +ATOM 4567 CG PHE C 291 -18.366 9.696 -82.328 1.00 55.71 C +ATOM 4568 CD1 PHE C 291 -17.941 8.956 -83.419 1.00 61.60 C +ATOM 4569 CD2 PHE C 291 -18.139 11.056 -82.318 1.00 59.17 C +ATOM 4570 CE1 PHE C 291 -17.301 9.557 -84.479 1.00 59.32 C +ATOM 4571 CE2 PHE C 291 -17.499 11.669 -83.378 1.00 67.91 C +ATOM 4572 CZ PHE C 291 -17.080 10.917 -84.461 1.00 67.49 C +ATOM 4573 N HIS C 292 -16.802 9.732 -79.117 1.00 57.20 N +ATOM 4574 CA HIS C 292 -15.565 10.416 -78.757 1.00 56.97 C +ATOM 4575 C HIS C 292 -14.588 9.464 -78.080 1.00 59.49 C +ATOM 4576 O HIS C 292 -13.379 9.532 -78.324 1.00 57.48 O +ATOM 4577 CB HIS C 292 -15.873 11.611 -77.855 1.00 52.50 C +ATOM 4578 CG HIS C 292 -16.578 12.730 -78.555 1.00 52.21 C +ATOM 4579 ND1 HIS C 292 -15.902 13.724 -79.229 1.00 56.17 N +ATOM 4580 CD2 HIS C 292 -17.896 13.010 -78.693 1.00 53.70 C +ATOM 4581 CE1 HIS C 292 -16.774 14.570 -79.750 1.00 59.37 C +ATOM 4582 NE2 HIS C 292 -17.991 14.161 -79.437 1.00 51.01 N +ATOM 4583 N LEU C 293 -15.098 8.562 -77.236 1.00 62.03 N +ATOM 4584 CA LEU C 293 -14.250 7.549 -76.611 1.00 63.58 C +ATOM 4585 C LEU C 293 -13.566 6.692 -77.669 1.00 60.82 C +ATOM 4586 O LEU C 293 -12.359 6.426 -77.596 1.00 53.69 O +ATOM 4587 CB LEU C 293 -15.095 6.681 -75.673 1.00 61.87 C +ATOM 4588 CG LEU C 293 -14.447 5.862 -74.547 1.00 59.62 C +ATOM 4589 CD1 LEU C 293 -13.529 4.767 -75.062 1.00 57.37 C +ATOM 4590 CD2 LEU C 293 -13.704 6.759 -73.586 1.00 60.01 C +ATOM 4591 N ASP C 294 -14.343 6.223 -78.646 1.00 58.94 N +ATOM 4592 CA ASP C 294 -13.789 5.428 -79.732 1.00 57.40 C +ATOM 4593 C ASP C 294 -12.846 6.258 -80.595 1.00 55.87 C +ATOM 4594 O ASP C 294 -11.801 5.766 -81.036 1.00 55.08 O +ATOM 4595 CB ASP C 294 -14.939 4.842 -80.549 1.00 52.90 C +ATOM 4596 CG ASP C 294 -14.481 4.180 -81.822 1.00 55.45 C +ATOM 4597 OD1 ASP C 294 -14.173 4.902 -82.795 1.00 56.51 O +ATOM 4598 OD2 ASP C 294 -14.427 2.933 -81.843 1.00 51.54 O +ATOM 4599 N ARG C 295 -13.187 7.526 -80.828 1.00 57.38 N +ATOM 4600 CA ARG C 295 -12.305 8.400 -81.593 1.00 62.58 C +ATOM 4601 C ARG C 295 -10.993 8.638 -80.860 1.00 60.68 C +ATOM 4602 O ARG C 295 -9.919 8.624 -81.475 1.00 54.46 O +ATOM 4603 CB ARG C 295 -13.005 9.731 -81.864 1.00 70.33 C +ATOM 4604 CG ARG C 295 -12.087 10.852 -82.331 1.00 67.06 C +ATOM 4605 CD ARG C 295 -12.776 12.195 -82.181 1.00 64.00 C +ATOM 4606 NE ARG C 295 -13.463 12.579 -83.407 1.00 58.74 N +ATOM 4607 CZ ARG C 295 -14.370 13.545 -83.477 1.00 61.36 C +ATOM 4608 NH1 ARG C 295 -14.705 14.219 -82.384 1.00 59.73 N +ATOM 4609 NH2 ARG C 295 -14.945 13.835 -84.636 1.00 62.66 N +ATOM 4610 N ILE C 296 -11.066 8.831 -79.539 1.00 60.62 N +ATOM 4611 CA ILE C 296 -9.886 9.145 -78.738 1.00 59.96 C +ATOM 4612 C ILE C 296 -8.922 7.966 -78.712 1.00 63.80 C +ATOM 4613 O ILE C 296 -7.697 8.155 -78.712 1.00 60.43 O +ATOM 4614 CB ILE C 296 -10.316 9.569 -77.320 1.00 56.43 C +ATOM 4615 CG1 ILE C 296 -10.382 11.094 -77.198 1.00 54.05 C +ATOM 4616 CG2 ILE C 296 -9.369 9.014 -76.267 1.00 64.11 C +ATOM 4617 CD1 ILE C 296 -11.307 11.765 -78.185 1.00 55.16 C +ATOM 4618 N LEU C 297 -9.446 6.740 -78.712 1.00 59.76 N +ATOM 4619 CA LEU C 297 -8.611 5.549 -78.767 1.00 57.96 C +ATOM 4620 C LEU C 297 -8.131 5.245 -80.175 1.00 57.82 C +ATOM 4621 O LEU C 297 -7.391 4.271 -80.367 1.00 50.55 O +ATOM 4622 CB LEU C 297 -9.382 4.343 -78.225 1.00 51.72 C +ATOM 4623 CG LEU C 297 -10.000 4.478 -76.837 1.00 48.94 C +ATOM 4624 CD1 LEU C 297 -10.721 3.203 -76.474 1.00 51.86 C +ATOM 4625 CD2 LEU C 297 -8.927 4.792 -75.815 1.00 58.55 C +ATOM 4626 N ASP C 298 -8.500 6.087 -81.143 1.00 62.14 N +ATOM 4627 CA ASP C 298 -8.120 5.927 -82.543 1.00 62.35 C +ATOM 4628 C ASP C 298 -8.578 4.584 -83.114 1.00 60.19 C +ATOM 4629 O ASP C 298 -7.928 4.017 -83.997 1.00 59.45 O +ATOM 4630 CB ASP C 298 -6.611 6.110 -82.720 1.00 62.28 C +ATOM 4631 CG ASP C 298 -6.250 6.683 -84.066 1.00 60.30 C +ATOM 4632 OD1 ASP C 298 -6.542 7.872 -84.318 1.00 57.56 O +ATOM 4633 OD2 ASP C 298 -5.688 5.927 -84.877 1.00 64.03 O +ATOM 4634 N PHE C 299 -9.711 4.075 -82.621 1.00 56.79 N +ATOM 4635 CA PHE C 299 -10.297 2.858 -83.173 1.00 53.29 C +ATOM 4636 C PHE C 299 -11.072 3.158 -84.447 1.00 53.94 C +ATOM 4637 O PHE C 299 -10.896 2.477 -85.465 1.00 54.37 O +ATOM 4638 CB PHE C 299 -11.221 2.194 -82.145 1.00 53.24 C +ATOM 4639 CG PHE C 299 -10.502 1.378 -81.114 1.00 50.39 C +ATOM 4640 CD1 PHE C 299 -9.296 0.770 -81.411 1.00 52.52 C +ATOM 4641 CD2 PHE C 299 -11.033 1.222 -79.845 1.00 44.71 C +ATOM 4642 CE1 PHE C 299 -8.633 0.021 -80.462 1.00 52.48 C +ATOM 4643 CE2 PHE C 299 -10.374 0.475 -78.892 1.00 46.70 C +ATOM 4644 CZ PHE C 299 -9.171 -0.127 -79.200 1.00 49.81 C +ATOM 4645 N ARG C 300 -11.930 4.181 -84.397 1.00 54.47 N +ATOM 4646 CA ARG C 300 -12.744 4.619 -85.531 1.00 56.46 C +ATOM 4647 C ARG C 300 -13.620 3.475 -86.051 1.00 52.27 C +ATOM 4648 O ARG C 300 -13.593 3.108 -87.226 1.00 54.44 O +ATOM 4649 CB ARG C 300 -11.856 5.215 -86.632 1.00 57.90 C +ATOM 4650 CG ARG C 300 -11.230 6.554 -86.246 1.00 52.35 C +ATOM 4651 CD ARG C 300 -9.930 6.822 -86.987 1.00 53.22 C +ATOM 4652 NE ARG C 300 -9.018 5.682 -86.915 1.00 55.65 N +ATOM 4653 CZ ARG C 300 -7.940 5.529 -87.680 1.00 57.85 C +ATOM 4654 NH1 ARG C 300 -7.634 6.446 -88.585 1.00 60.48 N +ATOM 4655 NH2 ARG C 300 -7.172 4.455 -87.546 1.00 53.68 N +ATOM 4656 N ARG C 301 -14.400 2.907 -85.135 1.00 47.85 N +ATOM 4657 CA ARG C 301 -15.328 1.836 -85.458 1.00 46.08 C +ATOM 4658 C ARG C 301 -16.771 2.207 -85.172 1.00 46.59 C +ATOM 4659 O ARG C 301 -17.649 1.353 -85.325 1.00 50.11 O +ATOM 4660 CB ARG C 301 -14.996 0.560 -84.670 1.00 51.34 C +ATOM 4661 CG ARG C 301 -13.537 0.368 -84.287 1.00 57.60 C +ATOM 4662 CD ARG C 301 -12.752 -0.372 -85.349 1.00 53.39 C +ATOM 4663 NE ARG C 301 -11.362 -0.573 -84.948 1.00 55.89 N +ATOM 4664 CZ ARG C 301 -10.954 -1.528 -84.117 1.00 56.68 C +ATOM 4665 NH1 ARG C 301 -11.829 -2.373 -83.583 1.00 50.02 N +ATOM 4666 NH2 ARG C 301 -9.668 -1.634 -83.814 1.00 59.94 N +ATOM 4667 N VAL C 302 -17.044 3.431 -84.730 1.00 48.17 N +ATOM 4668 CA VAL C 302 -18.404 3.828 -84.369 1.00 49.36 C +ATOM 4669 C VAL C 302 -18.910 4.824 -85.402 1.00 52.43 C +ATOM 4670 O VAL C 302 -18.121 5.620 -85.929 1.00 56.93 O +ATOM 4671 CB VAL C 302 -18.471 4.440 -82.961 1.00 41.49 C +ATOM 4672 CG1 VAL C 302 -18.165 3.400 -81.910 1.00 41.91 C +ATOM 4673 CG2 VAL C 302 -17.504 5.593 -82.856 1.00 48.39 C +ATOM 4674 N PRO C 303 -20.196 4.811 -85.732 1.00 47.01 N +ATOM 4675 CA PRO C 303 -20.741 5.857 -86.581 1.00 48.67 C +ATOM 4676 C PRO C 303 -20.815 7.168 -85.819 1.00 53.59 C +ATOM 4677 O PRO C 303 -21.134 7.182 -84.619 1.00 52.88 O +ATOM 4678 CB PRO C 303 -22.139 5.329 -86.935 1.00 42.90 C +ATOM 4679 CG PRO C 303 -22.502 4.470 -85.792 1.00 40.23 C +ATOM 4680 CD PRO C 303 -21.222 3.834 -85.333 1.00 46.58 C +ATOM 4681 N PRO C 304 -20.498 8.286 -86.472 1.00 50.57 N +ATOM 4682 CA PRO C 304 -20.541 9.580 -85.786 1.00 48.96 C +ATOM 4683 C PRO C 304 -21.938 9.888 -85.279 1.00 52.14 C +ATOM 4684 O PRO C 304 -22.936 9.670 -85.969 1.00 51.93 O +ATOM 4685 CB PRO C 304 -20.108 10.569 -86.872 1.00 50.98 C +ATOM 4686 CG PRO C 304 -19.334 9.750 -87.842 1.00 50.21 C +ATOM 4687 CD PRO C 304 -19.997 8.412 -87.850 1.00 49.70 C +ATOM 4688 N VAL C 305 -22.000 10.408 -84.061 1.00 52.12 N +ATOM 4689 CA VAL C 305 -23.263 10.751 -83.425 1.00 51.66 C +ATOM 4690 C VAL C 305 -23.089 12.093 -82.726 1.00 52.89 C +ATOM 4691 O VAL C 305 -22.021 12.385 -82.177 1.00 51.21 O +ATOM 4692 CB VAL C 305 -23.713 9.634 -82.455 1.00 49.43 C +ATOM 4693 CG1 VAL C 305 -22.580 9.261 -81.531 1.00 53.29 C +ATOM 4694 CG2 VAL C 305 -24.961 10.035 -81.668 1.00 49.24 C +ATOM 4695 N ALA C 306 -24.113 12.939 -82.814 1.00 48.53 N +ATOM 4696 CA ALA C 306 -24.108 14.250 -82.186 1.00 47.19 C +ATOM 4697 C ALA C 306 -25.457 14.488 -81.525 1.00 49.04 C +ATOM 4698 O ALA C 306 -26.486 13.999 -81.997 1.00 47.24 O +ATOM 4699 CB ALA C 306 -23.800 15.355 -83.202 1.00 55.60 C +ATOM 4700 N GLY C 307 -25.445 15.246 -80.433 1.00 48.35 N +ATOM 4701 CA GLY C 307 -26.645 15.507 -79.645 1.00 53.45 C +ATOM 4702 C GLY C 307 -27.322 16.803 -80.053 1.00 51.26 C +ATOM 4703 O GLY C 307 -26.658 17.771 -80.412 1.00 50.77 O +ATOM 4704 N ARG C 308 -28.649 16.811 -79.990 1.00 49.30 N +ATOM 4705 CA ARG C 308 -29.431 17.942 -80.466 1.00 53.11 C +ATOM 4706 C ARG C 308 -30.665 18.153 -79.594 1.00 59.43 C +ATOM 4707 O ARG C 308 -31.351 17.193 -79.235 1.00 64.60 O +ATOM 4708 CB ARG C 308 -29.827 17.716 -81.927 1.00 54.76 C +ATOM 4709 CG ARG C 308 -30.686 18.797 -82.529 1.00 58.62 C +ATOM 4710 CD ARG C 308 -30.982 18.483 -83.975 1.00 51.84 C +ATOM 4711 NE ARG C 308 -31.932 19.425 -84.551 1.00 57.84 N +ATOM 4712 CZ ARG C 308 -32.120 19.585 -85.855 1.00 60.07 C +ATOM 4713 NH1 ARG C 308 -31.408 18.871 -86.718 1.00 57.55 N +ATOM 4714 NH2 ARG C 308 -33.014 20.462 -86.296 1.00 63.69 N +ATOM 4715 N LEU C 309 -30.955 19.417 -79.275 1.00 60.76 N +ATOM 4716 CA LEU C 309 -32.170 19.803 -78.550 1.00 61.27 C +ATOM 4717 C LEU C 309 -33.312 19.929 -79.551 1.00 64.03 C +ATOM 4718 O LEU C 309 -33.442 20.949 -80.232 1.00 77.86 O +ATOM 4719 CB LEU C 309 -31.962 21.123 -77.815 1.00 69.25 C +ATOM 4720 CG LEU C 309 -30.892 21.189 -76.725 1.00 73.99 C +ATOM 4721 CD1 LEU C 309 -30.659 22.619 -76.232 1.00 65.62 C +ATOM 4722 CD2 LEU C 309 -31.293 20.290 -75.575 1.00 80.90 C +ATOM 4723 N VAL C 310 -34.149 18.905 -79.656 1.00 54.71 N +ATOM 4724 CA VAL C 310 -35.190 18.898 -80.678 1.00 54.30 C +ATOM 4725 C VAL C 310 -36.515 19.364 -80.084 1.00 51.02 C +ATOM 4726 O VAL C 310 -36.790 19.186 -78.893 1.00 53.57 O +ATOM 4727 CB VAL C 310 -35.317 17.506 -81.332 1.00 50.02 C +ATOM 4728 CG1 VAL C 310 -33.956 17.036 -81.840 1.00 47.45 C +ATOM 4729 CG2 VAL C 310 -35.899 16.514 -80.362 1.00 58.32 C +ATOM 4730 N ASN C 311 -37.333 19.996 -80.931 1.00 49.38 N +ATOM 4731 CA ASN C 311 -38.681 20.444 -80.585 1.00 49.84 C +ATOM 4732 C ASN C 311 -39.665 19.326 -80.902 1.00 48.40 C +ATOM 4733 O ASN C 311 -39.849 18.973 -82.071 1.00 52.25 O +ATOM 4734 CB ASN C 311 -39.027 21.717 -81.372 1.00 58.74 C +ATOM 4735 CG ASN C 311 -40.405 22.306 -81.025 1.00 58.70 C +ATOM 4736 OD1 ASN C 311 -41.362 21.574 -80.769 1.00 60.50 O +ATOM 4737 ND2 ASN C 311 -40.511 23.639 -81.056 1.00 47.83 N +ATOM 4738 N MET C 312 -40.336 18.810 -79.875 1.00 46.93 N +ATOM 4739 CA MET C 312 -41.246 17.691 -80.092 1.00 53.24 C +ATOM 4740 C MET C 312 -42.538 18.090 -80.786 1.00 53.54 C +ATOM 4741 O MET C 312 -43.350 17.212 -81.100 1.00 54.60 O +ATOM 4742 CB MET C 312 -41.556 17.000 -78.763 1.00 58.38 C +ATOM 4743 CG MET C 312 -41.664 17.934 -77.573 1.00 67.54 C +ATOM 4744 SD MET C 312 -42.438 17.181 -76.124 1.00 83.67 S +ATOM 4745 CE MET C 312 -41.762 15.529 -76.159 1.00 65.10 C +ATOM 4746 N THR C 313 -42.757 19.373 -81.049 1.00 53.85 N +ATOM 4747 CA THR C 313 -43.946 19.775 -81.790 1.00 65.23 C +ATOM 4748 C THR C 313 -43.676 19.812 -83.292 1.00 68.26 C +ATOM 4749 O THR C 313 -44.318 19.093 -84.061 1.00 63.73 O +ATOM 4750 CB THR C 313 -44.446 21.129 -81.281 1.00 74.46 C +ATOM 4751 OG1 THR C 313 -44.958 20.973 -79.949 1.00 67.09 O +ATOM 4752 CG2 THR C 313 -45.531 21.686 -82.200 1.00 76.60 C +ATOM 4753 N ARG C 314 -42.712 20.626 -83.719 1.00 68.41 N +ATOM 4754 CA ARG C 314 -42.453 20.806 -85.140 1.00 63.64 C +ATOM 4755 C ARG C 314 -41.408 19.847 -85.694 1.00 65.16 C +ATOM 4756 O ARG C 314 -41.376 19.635 -86.912 1.00 73.80 O +ATOM 4757 CB ARG C 314 -42.010 22.248 -85.415 1.00 65.02 C +ATOM 4758 CG ARG C 314 -40.669 22.621 -84.805 1.00 54.40 C +ATOM 4759 CD ARG C 314 -40.258 24.026 -85.195 1.00 47.23 C +ATOM 4760 NE ARG C 314 -38.938 24.352 -84.667 1.00 55.92 N +ATOM 4761 CZ ARG C 314 -37.795 24.078 -85.287 1.00 59.81 C +ATOM 4762 NH1 ARG C 314 -36.636 24.407 -84.728 1.00 59.63 N +ATOM 4763 NH2 ARG C 314 -37.811 23.480 -86.470 1.00 54.98 N +ATOM 4764 N GLU C 315 -40.571 19.242 -84.846 1.00 54.95 N +ATOM 4765 CA GLU C 315 -39.547 18.324 -85.331 1.00 55.01 C +ATOM 4766 C GLU C 315 -39.854 16.852 -85.078 1.00 55.99 C +ATOM 4767 O GLU C 315 -39.129 15.995 -85.596 1.00 50.73 O +ATOM 4768 CB GLU C 315 -38.175 18.661 -84.718 1.00 47.53 C +ATOM 4769 CG GLU C 315 -37.636 20.039 -85.078 1.00 48.34 C +ATOM 4770 CD GLU C 315 -36.165 20.200 -84.722 1.00 46.88 C +ATOM 4771 OE1 GLU C 315 -35.312 19.768 -85.526 1.00 43.44 O +ATOM 4772 OE2 GLU C 315 -35.854 20.774 -83.657 1.00 47.63 O +ATOM 4773 N ILE C 316 -40.916 16.532 -84.334 1.00 59.99 N +ATOM 4774 CA ILE C 316 -41.285 15.144 -84.060 1.00 52.67 C +ATOM 4775 C ILE C 316 -42.743 14.904 -84.441 1.00 50.41 C +ATOM 4776 O ILE C 316 -43.036 14.134 -85.360 1.00 52.74 O +ATOM 4777 CB ILE C 316 -41.056 14.772 -82.582 1.00 49.55 C +ATOM 4778 CG1 ILE C 316 -39.610 15.037 -82.142 1.00 45.56 C +ATOM 4779 CG2 ILE C 316 -41.406 13.312 -82.362 1.00 45.31 C +ATOM 4780 CD1 ILE C 316 -38.589 14.084 -82.704 1.00 44.09 C +ATOM 4781 N ARG C 317 -43.667 15.544 -83.719 1.00 49.95 N +ATOM 4782 CA ARG C 317 -45.087 15.226 -83.861 1.00 55.00 C +ATOM 4783 C ARG C 317 -45.654 15.694 -85.197 1.00 67.04 C +ATOM 4784 O ARG C 317 -46.355 14.940 -85.883 1.00 65.45 O +ATOM 4785 CB ARG C 317 -45.884 15.848 -82.719 1.00 57.05 C +ATOM 4786 CG ARG C 317 -47.378 15.577 -82.829 1.00 62.65 C +ATOM 4787 CD ARG C 317 -48.150 16.388 -81.808 1.00 70.17 C +ATOM 4788 NE ARG C 317 -48.018 17.825 -82.032 1.00 72.46 N +ATOM 4789 CZ ARG C 317 -48.469 18.754 -81.195 1.00 71.86 C +ATOM 4790 NH1 ARG C 317 -49.079 18.403 -80.070 1.00 72.41 N +ATOM 4791 NH2 ARG C 317 -48.305 20.037 -81.480 1.00 72.65 N +ATOM 4792 N ASP C 318 -45.393 16.946 -85.570 1.00 70.34 N +ATOM 4793 CA ASP C 318 -46.033 17.544 -86.737 1.00 68.18 C +ATOM 4794 C ASP C 318 -45.351 17.175 -88.045 1.00 66.24 C +ATOM 4795 O ASP C 318 -45.742 17.696 -89.094 1.00 70.85 O +ATOM 4796 CB ASP C 318 -46.066 19.071 -86.600 1.00 73.49 C +ATOM 4797 CG ASP C 318 -46.811 19.538 -85.357 1.00 75.22 C +ATOM 4798 OD1 ASP C 318 -47.305 18.679 -84.594 1.00 81.71 O +ATOM 4799 OD2 ASP C 318 -46.872 20.767 -85.125 1.00 70.25 O +ATOM 4800 N VAL C 319 -44.362 16.285 -88.015 1.00 60.91 N +ATOM 4801 CA VAL C 319 -43.648 15.902 -89.227 1.00 60.06 C +ATOM 4802 C VAL C 319 -43.529 14.385 -89.292 1.00 60.72 C +ATOM 4803 O VAL C 319 -42.497 13.847 -89.708 1.00 60.64 O +ATOM 4804 CB VAL C 319 -42.263 16.573 -89.303 1.00 53.24 C +ATOM 4805 CG1 VAL C 319 -42.407 18.059 -89.576 1.00 57.41 C +ATOM 4806 CG2 VAL C 319 -41.494 16.353 -88.022 1.00 56.64 C +ATOM 4807 N THR C 320 -44.581 13.682 -88.879 1.00 57.44 N +ATOM 4808 CA THR C 320 -44.611 12.231 -88.996 1.00 55.85 C +ATOM 4809 C THR C 320 -45.993 11.793 -89.447 1.00 54.67 C +ATOM 4810 O THR C 320 -47.003 12.248 -88.903 1.00 49.73 O +ATOM 4811 CB THR C 320 -44.239 11.536 -87.682 1.00 50.83 C +ATOM 4812 OG1 THR C 320 -44.464 10.128 -87.817 1.00 54.91 O +ATOM 4813 CG2 THR C 320 -45.075 12.063 -86.538 1.00 50.24 C +ATOM 4814 N ARG C 321 -46.028 10.948 -90.476 1.00 61.79 N +ATOM 4815 CA ARG C 321 -47.245 10.285 -90.923 1.00 69.21 C +ATOM 4816 C ARG C 321 -47.381 8.879 -90.343 1.00 70.12 C +ATOM 4817 O ARG C 321 -48.141 8.060 -90.876 1.00 59.02 O +ATOM 4818 CB ARG C 321 -47.289 10.252 -92.452 1.00 73.83 C +ATOM 4819 CG ARG C 321 -45.955 9.912 -93.113 1.00 77.33 C +ATOM 4820 CD ARG C 321 -46.100 9.696 -94.616 1.00 82.22 C +ATOM 4821 NE ARG C 321 -46.472 10.936 -95.293 1.00 90.85 N +ATOM 4822 CZ ARG C 321 -45.602 11.792 -95.817 1.00 86.57 C +ATOM 4823 NH1 ARG C 321 -44.301 11.550 -95.736 1.00 84.22 N +ATOM 4824 NH2 ARG C 321 -46.033 12.896 -96.412 1.00 68.96 N +ATOM 4825 N ASP C 322 -46.675 8.596 -89.248 1.00 70.25 N +ATOM 4826 CA ASP C 322 -46.711 7.297 -88.583 1.00 69.92 C +ATOM 4827 C ASP C 322 -47.896 7.274 -87.620 1.00 70.70 C +ATOM 4828 O ASP C 322 -47.902 7.992 -86.614 1.00 65.12 O +ATOM 4829 CB ASP C 322 -45.390 7.051 -87.855 1.00 60.73 C +ATOM 4830 CG ASP C 322 -45.276 5.646 -87.292 1.00 69.94 C +ATOM 4831 OD1 ASP C 322 -46.065 5.298 -86.391 1.00 76.42 O +ATOM 4832 OD2 ASP C 322 -44.377 4.897 -87.732 1.00 70.76 O +ATOM 4833 N LYS C 323 -48.898 6.440 -87.925 1.00 69.19 N +ATOM 4834 CA LYS C 323 -50.107 6.389 -87.106 1.00 66.51 C +ATOM 4835 C LYS C 323 -49.817 5.880 -85.698 1.00 69.96 C +ATOM 4836 O LYS C 323 -50.466 6.311 -84.738 1.00 67.36 O +ATOM 4837 CB LYS C 323 -51.153 5.491 -87.775 1.00 68.88 C +ATOM 4838 CG LYS C 323 -51.505 5.882 -89.207 1.00 92.27 C +ATOM 4839 CD LYS C 323 -52.510 4.913 -89.841 1.00 80.55 C +ATOM 4840 CE LYS C 323 -53.839 4.904 -89.105 1.00 75.63 C +ATOM 4841 NZ LYS C 323 -54.797 3.947 -89.728 1.00 60.64 N +ATOM 4842 N LYS C 324 -48.842 4.977 -85.557 1.00 72.92 N +ATOM 4843 CA LYS C 324 -48.511 4.416 -84.251 1.00 62.82 C +ATOM 4844 C LYS C 324 -47.844 5.457 -83.363 1.00 58.14 C +ATOM 4845 O LYS C 324 -48.235 5.647 -82.206 1.00 58.23 O +ATOM 4846 CB LYS C 324 -47.591 3.204 -84.422 1.00 71.50 C +ATOM 4847 CG LYS C 324 -47.809 2.424 -85.715 1.00 79.16 C +ATOM 4848 CD LYS C 324 -46.666 1.445 -85.983 1.00 79.23 C +ATOM 4849 CE LYS C 324 -46.501 0.452 -84.838 1.00 82.01 C +ATOM 4850 NZ LYS C 324 -47.779 -0.257 -84.531 1.00 76.22 N +ATOM 4851 N LEU C 325 -46.818 6.128 -83.890 1.00 61.23 N +ATOM 4852 CA LEU C 325 -46.055 7.087 -83.102 1.00 53.86 C +ATOM 4853 C LEU C 325 -46.900 8.297 -82.743 1.00 51.32 C +ATOM 4854 O LEU C 325 -46.794 8.829 -81.632 1.00 46.53 O +ATOM 4855 CB LEU C 325 -44.805 7.512 -83.877 1.00 52.64 C +ATOM 4856 CG LEU C 325 -43.735 8.412 -83.254 1.00 41.42 C +ATOM 4857 CD1 LEU C 325 -44.035 9.863 -83.524 1.00 46.68 C +ATOM 4858 CD2 LEU C 325 -43.592 8.175 -81.767 1.00 44.94 C +ATOM 4859 N TRP C 326 -47.733 8.758 -83.672 1.00 54.43 N +ATOM 4860 CA TRP C 326 -48.454 9.995 -83.417 1.00 61.34 C +ATOM 4861 C TRP C 326 -49.568 9.802 -82.395 1.00 65.77 C +ATOM 4862 O TRP C 326 -49.800 10.692 -81.567 1.00 67.17 O +ATOM 4863 CB TRP C 326 -48.993 10.569 -84.728 1.00 64.21 C +ATOM 4864 CG TRP C 326 -49.642 11.902 -84.543 1.00 64.21 C +ATOM 4865 CD1 TRP C 326 -49.030 13.124 -84.560 1.00 60.10 C +ATOM 4866 CD2 TRP C 326 -51.037 12.153 -84.340 1.00 62.01 C +ATOM 4867 NE1 TRP C 326 -49.957 14.118 -84.357 1.00 67.08 N +ATOM 4868 CE2 TRP C 326 -51.197 13.547 -84.223 1.00 70.85 C +ATOM 4869 CE3 TRP C 326 -52.165 11.332 -84.238 1.00 54.10 C +ATOM 4870 CZ2 TRP C 326 -52.441 14.138 -84.011 1.00 66.96 C +ATOM 4871 CZ3 TRP C 326 -53.396 11.920 -84.028 1.00 52.48 C +ATOM 4872 CH2 TRP C 326 -53.525 13.309 -83.916 1.00 54.42 C +ATOM 4873 N ARG C 327 -50.229 8.639 -82.392 1.00 62.71 N +ATOM 4874 CA ARG C 327 -51.367 8.437 -81.498 1.00 61.35 C +ATOM 4875 C ARG C 327 -50.976 8.357 -80.027 1.00 59.18 C +ATOM 4876 O ARG C 327 -51.861 8.199 -79.179 1.00 61.53 O +ATOM 4877 CB ARG C 327 -52.130 7.169 -81.889 1.00 56.43 C +ATOM 4878 CG ARG C 327 -52.970 7.323 -83.130 1.00 57.51 C +ATOM 4879 CD ARG C 327 -54.359 6.756 -82.915 1.00 74.63 C +ATOM 4880 NE ARG C 327 -54.933 6.229 -84.149 1.00 92.00 N +ATOM 4881 CZ ARG C 327 -54.810 4.967 -84.545 1.00 94.12 C +ATOM 4882 NH1 ARG C 327 -54.132 4.102 -83.798 1.00 95.92 N +ATOM 4883 NH2 ARG C 327 -55.365 4.569 -85.684 1.00 84.51 N +ATOM 4884 N THR C 328 -49.697 8.494 -79.690 1.00 54.79 N +ATOM 4885 CA THR C 328 -49.258 8.460 -78.304 1.00 54.42 C +ATOM 4886 C THR C 328 -48.834 9.835 -77.815 1.00 57.25 C +ATOM 4887 O THR C 328 -48.228 9.944 -76.745 1.00 58.03 O +ATOM 4888 CB THR C 328 -48.111 7.465 -78.114 1.00 54.50 C +ATOM 4889 OG1 THR C 328 -46.918 7.987 -78.709 1.00 51.96 O +ATOM 4890 CG2 THR C 328 -48.452 6.128 -78.762 1.00 53.08 C +ATOM 4891 N PHE C 329 -49.110 10.883 -78.585 1.00 56.85 N +ATOM 4892 CA PHE C 329 -48.751 12.241 -78.188 1.00 56.80 C +ATOM 4893 C PHE C 329 -49.891 12.807 -77.353 1.00 54.09 C +ATOM 4894 O PHE C 329 -50.917 13.233 -77.888 1.00 56.42 O +ATOM 4895 CB PHE C 329 -48.452 13.107 -79.405 1.00 54.97 C +ATOM 4896 CG PHE C 329 -46.986 13.292 -79.667 1.00 50.06 C +ATOM 4897 CD1 PHE C 329 -46.292 12.397 -80.461 1.00 51.01 C +ATOM 4898 CD2 PHE C 329 -46.298 14.355 -79.104 1.00 48.91 C +ATOM 4899 CE1 PHE C 329 -44.941 12.568 -80.698 1.00 52.57 C +ATOM 4900 CE2 PHE C 329 -44.949 14.530 -79.336 1.00 46.40 C +ATOM 4901 CZ PHE C 329 -44.269 13.636 -80.134 1.00 49.24 C +ATOM 4902 N PHE C 330 -49.729 12.764 -76.035 1.00 53.59 N +ATOM 4903 CA PHE C 330 -50.691 13.305 -75.088 1.00 58.50 C +ATOM 4904 C PHE C 330 -50.077 14.459 -74.299 1.00 68.66 C +ATOM 4905 O PHE C 330 -48.854 14.629 -74.248 1.00 62.30 O +ATOM 4906 CB PHE C 330 -51.177 12.211 -74.132 1.00 56.84 C +ATOM 4907 CG PHE C 330 -50.105 11.694 -73.218 1.00 58.33 C +ATOM 4908 CD1 PHE C 330 -49.244 10.696 -73.632 1.00 57.51 C +ATOM 4909 CD2 PHE C 330 -49.950 12.220 -71.949 1.00 64.94 C +ATOM 4910 CE1 PHE C 330 -48.255 10.228 -72.793 1.00 55.28 C +ATOM 4911 CE2 PHE C 330 -48.962 11.759 -71.108 1.00 61.05 C +ATOM 4912 CZ PHE C 330 -48.117 10.758 -71.528 1.00 55.53 C +ATOM 4913 N VAL C 331 -50.947 15.251 -73.669 1.00 74.98 N +ATOM 4914 CA VAL C 331 -50.540 16.358 -72.808 1.00 66.42 C +ATOM 4915 C VAL C 331 -50.792 15.961 -71.361 1.00 63.54 C +ATOM 4916 O VAL C 331 -51.904 15.544 -71.008 1.00 50.29 O +ATOM 4917 CB VAL C 331 -51.293 17.653 -73.153 1.00 68.42 C +ATOM 4918 CG1 VAL C 331 -50.683 18.836 -72.394 1.00 67.67 C +ATOM 4919 CG2 VAL C 331 -51.297 17.882 -74.659 1.00 74.56 C +ATOM 4920 N SER C 332 -49.783 16.144 -70.521 1.00 63.72 N +ATOM 4921 CA SER C 332 -49.805 15.649 -69.152 1.00 61.72 C +ATOM 4922 C SER C 332 -50.510 16.645 -68.244 1.00 67.00 C +ATOM 4923 O SER C 332 -50.775 17.787 -68.628 1.00 69.94 O +ATOM 4924 CB SER C 332 -48.375 15.391 -68.683 1.00 52.84 C +ATOM 4925 OG SER C 332 -47.676 16.601 -68.449 1.00 53.79 O +ATOM 4926 N PRO C 333 -50.869 16.235 -67.023 1.00 64.17 N +ATOM 4927 CA PRO C 333 -51.448 17.204 -66.081 1.00 59.00 C +ATOM 4928 C PRO C 333 -50.522 18.369 -65.767 1.00 63.46 C +ATOM 4929 O PRO C 333 -51.014 19.445 -65.408 1.00 68.40 O +ATOM 4930 CB PRO C 333 -51.741 16.353 -64.839 1.00 56.80 C +ATOM 4931 CG PRO C 333 -51.970 14.987 -65.379 1.00 48.09 C +ATOM 4932 CD PRO C 333 -51.011 14.851 -66.533 1.00 60.40 C +ATOM 4933 N ALA C 334 -49.207 18.208 -65.921 1.00 55.22 N +ATOM 4934 CA ALA C 334 -48.283 19.325 -65.770 1.00 58.32 C +ATOM 4935 C ALA C 334 -48.206 20.194 -67.020 1.00 64.76 C +ATOM 4936 O ALA C 334 -47.265 20.984 -67.149 1.00 63.14 O +ATOM 4937 CB ALA C 334 -46.887 18.814 -65.407 1.00 58.18 C +ATOM 4938 N ASN C 335 -49.168 20.042 -67.935 1.00 71.73 N +ATOM 4939 CA ASN C 335 -49.256 20.803 -69.186 1.00 73.10 C +ATOM 4940 C ASN C 335 -48.012 20.635 -70.054 1.00 73.80 C +ATOM 4941 O ASN C 335 -47.684 21.503 -70.866 1.00 82.20 O +ATOM 4942 CB ASN C 335 -49.537 22.286 -68.932 1.00 71.34 C +ATOM 4943 CG ASN C 335 -50.310 22.927 -70.069 1.00 80.22 C +ATOM 4944 OD1 ASN C 335 -51.539 22.863 -70.104 1.00 82.28 O +ATOM 4945 ND2 ASN C 335 -49.595 23.552 -71.004 1.00 85.79 N +ATOM 4946 N ASN C 336 -47.317 19.517 -69.899 1.00 66.80 N +ATOM 4947 CA ASN C 336 -46.193 19.178 -70.753 1.00 63.41 C +ATOM 4948 C ASN C 336 -46.635 18.168 -71.802 1.00 71.74 C +ATOM 4949 O ASN C 336 -47.611 17.434 -71.615 1.00 62.81 O +ATOM 4950 CB ASN C 336 -45.030 18.622 -69.937 1.00 55.70 C +ATOM 4951 CG ASN C 336 -44.562 19.589 -68.886 1.00 61.68 C +ATOM 4952 OD1 ASN C 336 -44.767 20.793 -69.011 1.00 67.11 O +ATOM 4953 ND2 ASN C 336 -43.935 19.073 -67.838 1.00 65.70 N +ATOM 4954 N ILE C 337 -45.947 18.186 -72.937 1.00 78.68 N +ATOM 4955 CA ILE C 337 -46.224 17.255 -74.023 1.00 75.59 C +ATOM 4956 C ILE C 337 -45.364 16.013 -73.830 1.00 68.18 C +ATOM 4957 O ILE C 337 -44.175 16.102 -73.488 1.00 52.65 O +ATOM 4958 CB ILE C 337 -45.974 17.908 -75.396 1.00 70.92 C +ATOM 4959 CG1 ILE C 337 -46.644 19.281 -75.467 1.00 76.41 C +ATOM 4960 CG2 ILE C 337 -46.550 17.038 -76.500 1.00 58.79 C +ATOM 4961 CD1 ILE C 337 -46.469 19.986 -76.803 1.00 79.25 C +ATOM 4962 N CYS C 338 -45.979 14.847 -74.022 1.00 72.62 N +ATOM 4963 CA CYS C 338 -45.310 13.569 -73.835 1.00 67.23 C +ATOM 4964 C CYS C 338 -45.670 12.628 -74.975 1.00 58.86 C +ATOM 4965 O CYS C 338 -46.735 12.734 -75.590 1.00 54.92 O +ATOM 4966 CB CYS C 338 -45.700 12.900 -72.517 1.00 67.45 C +ATOM 4967 SG CYS C 338 -45.497 13.891 -71.047 1.00 73.80 S +ATOM 4968 N PHE C 339 -44.785 11.665 -75.206 1.00 54.55 N +ATOM 4969 CA PHE C 339 -45.037 10.586 -76.146 1.00 54.49 C +ATOM 4970 C PHE C 339 -44.186 9.401 -75.726 1.00 61.41 C +ATOM 4971 O PHE C 339 -43.107 9.573 -75.150 1.00 58.98 O +ATOM 4972 CB PHE C 339 -44.705 11.002 -77.582 1.00 54.27 C +ATOM 4973 CG PHE C 339 -43.234 10.966 -77.899 1.00 51.06 C +ATOM 4974 CD1 PHE C 339 -42.388 11.968 -77.454 1.00 52.02 C +ATOM 4975 CD2 PHE C 339 -42.703 9.943 -78.665 1.00 51.24 C +ATOM 4976 CE1 PHE C 339 -41.038 11.935 -77.747 1.00 46.49 C +ATOM 4977 CE2 PHE C 339 -41.356 9.909 -78.964 1.00 48.71 C +ATOM 4978 CZ PHE C 339 -40.523 10.906 -78.503 1.00 44.12 C +ATOM 4979 N TYR C 340 -44.672 8.199 -76.031 1.00 58.58 N +ATOM 4980 CA TYR C 340 -43.950 6.995 -75.637 1.00 60.21 C +ATOM 4981 C TYR C 340 -43.714 6.072 -76.828 1.00 59.99 C +ATOM 4982 O TYR C 340 -42.738 5.315 -76.843 1.00 63.64 O +ATOM 4983 CB TYR C 340 -44.685 6.262 -74.503 1.00 50.67 C +ATOM 4984 CG TYR C 340 -46.172 6.063 -74.691 1.00 43.99 C +ATOM 4985 CD1 TYR C 340 -47.070 7.078 -74.401 1.00 44.70 C +ATOM 4986 CD2 TYR C 340 -46.680 4.847 -75.116 1.00 48.77 C +ATOM 4987 CE1 TYR C 340 -48.434 6.895 -74.562 1.00 50.42 C +ATOM 4988 CE2 TYR C 340 -48.040 4.653 -75.277 1.00 50.88 C +ATOM 4989 CZ TYR C 340 -48.912 5.679 -74.998 1.00 48.62 C +ATOM 4990 OH TYR C 340 -50.267 5.486 -75.160 1.00 42.46 O +ATOM 4991 N GLY C 341 -44.569 6.135 -77.837 1.00 49.93 N +ATOM 4992 CA GLY C 341 -44.384 5.279 -78.987 1.00 50.84 C +ATOM 4993 C GLY C 341 -45.005 3.911 -78.778 1.00 62.28 C +ATOM 4994 O GLY C 341 -45.948 3.730 -78.003 1.00 64.20 O +ATOM 4995 N GLU C 342 -44.480 2.937 -79.512 1.00 65.83 N +ATOM 4996 CA GLU C 342 -45.004 1.578 -79.452 1.00 75.00 C +ATOM 4997 C GLU C 342 -43.880 0.582 -79.729 1.00 64.90 C +ATOM 4998 O GLU C 342 -43.913 -0.179 -80.692 1.00 63.77 O +ATOM 4999 CB GLU C 342 -46.162 1.412 -80.437 1.00 85.61 C +ATOM 5000 CG GLU C 342 -47.406 0.730 -79.866 1.00 86.07 C +ATOM 5001 CD GLU C 342 -48.621 0.851 -80.782 1.00 96.46 C +ATOM 5002 OE1 GLU C 342 -48.444 0.957 -82.015 1.00 97.52 O +ATOM 5003 OE2 GLU C 342 -49.760 0.837 -80.268 1.00111.18 O +ATOM 5004 N CYS C 343 -42.841 0.585 -78.893 1.00 57.26 N +ATOM 5005 CA CYS C 343 -41.822 -0.454 -78.999 1.00 64.53 C +ATOM 5006 C CYS C 343 -42.145 -1.609 -78.054 1.00 63.63 C +ATOM 5007 O CYS C 343 -43.275 -2.102 -78.042 1.00 71.44 O +ATOM 5008 CB CYS C 343 -40.430 0.119 -78.722 1.00 64.92 C +ATOM 5009 SG CYS C 343 -40.132 0.533 -77.000 1.00 61.49 S +ATOM 5010 N SER C 344 -41.183 -2.029 -77.230 1.00 63.48 N +ATOM 5011 CA SER C 344 -41.378 -3.190 -76.363 1.00 64.87 C +ATOM 5012 C SER C 344 -40.837 -2.959 -74.956 1.00 57.53 C +ATOM 5013 O SER C 344 -41.389 -3.484 -73.989 1.00 52.01 O +ATOM 5014 CB SER C 344 -40.729 -4.436 -76.991 1.00 58.93 C +ATOM 5015 OG SER C 344 -39.312 -4.341 -76.987 1.00 57.33 O +ATOM 5016 N TYR C 345 -39.748 -2.212 -74.833 1.00 61.29 N +ATOM 5017 CA TYR C 345 -39.143 -1.867 -73.555 1.00 57.99 C +ATOM 5018 C TYR C 345 -39.424 -0.406 -73.216 1.00 59.20 C +ATOM 5019 O TYR C 345 -38.942 0.496 -73.912 1.00 62.54 O +ATOM 5020 CB TYR C 345 -37.635 -2.111 -73.582 1.00 61.45 C +ATOM 5021 CG TYR C 345 -37.221 -3.371 -72.873 1.00 60.16 C +ATOM 5022 CD1 TYR C 345 -38.136 -4.376 -72.616 1.00 54.40 C +ATOM 5023 CD2 TYR C 345 -35.903 -3.560 -72.475 1.00 58.47 C +ATOM 5024 CE1 TYR C 345 -37.756 -5.532 -71.975 1.00 55.80 C +ATOM 5025 CE2 TYR C 345 -35.516 -4.708 -71.836 1.00 58.38 C +ATOM 5026 CZ TYR C 345 -36.444 -5.694 -71.582 1.00 58.64 C +ATOM 5027 OH TYR C 345 -36.050 -6.848 -70.944 1.00 59.75 O +ATOM 5028 N TYR C 346 -40.157 -0.183 -72.121 1.00 60.97 N +ATOM 5029 CA TYR C 346 -40.430 1.153 -71.590 1.00 55.56 C +ATOM 5030 C TYR C 346 -41.150 2.019 -72.623 1.00 61.83 C +ATOM 5031 O TYR C 346 -40.895 3.218 -72.740 1.00 63.76 O +ATOM 5032 CB TYR C 346 -39.140 1.826 -71.098 1.00 51.92 C +ATOM 5033 CG TYR C 346 -38.247 0.923 -70.267 1.00 53.71 C +ATOM 5034 CD1 TYR C 346 -38.765 0.159 -69.225 1.00 59.23 C +ATOM 5035 CD2 TYR C 346 -36.885 0.830 -70.528 1.00 54.36 C +ATOM 5036 CE1 TYR C 346 -37.943 -0.671 -68.464 1.00 62.11 C +ATOM 5037 CE2 TYR C 346 -36.058 0.005 -69.773 1.00 56.38 C +ATOM 5038 CZ TYR C 346 -36.590 -0.742 -68.744 1.00 61.50 C +ATOM 5039 OH TYR C 346 -35.763 -1.559 -68.001 1.00 57.82 O +ATOM 5040 N CYS C 347 -42.074 1.409 -73.364 1.00 62.18 N +ATOM 5041 CA CYS C 347 -42.919 2.117 -74.322 1.00 61.15 C +ATOM 5042 C CYS C 347 -44.367 2.047 -73.850 1.00 56.64 C +ATOM 5043 O CYS C 347 -45.223 1.382 -74.434 1.00 53.90 O +ATOM 5044 CB CYS C 347 -42.761 1.532 -75.747 1.00 67.45 C +ATOM 5045 SG CYS C 347 -41.324 2.148 -76.678 1.00 85.37 S +ATOM 5046 N SER C 348 -44.630 2.764 -72.762 1.00 56.65 N +ATOM 5047 CA SER C 348 -45.967 2.854 -72.209 1.00 56.36 C +ATOM 5048 C SER C 348 -46.109 4.220 -71.563 1.00 51.66 C +ATOM 5049 O SER C 348 -45.142 4.977 -71.448 1.00 50.77 O +ATOM 5050 CB SER C 348 -46.231 1.713 -71.219 1.00 59.86 C +ATOM 5051 OG SER C 348 -45.142 1.581 -70.321 1.00 61.91 O +ATOM 5052 N THR C 349 -47.328 4.516 -71.112 1.00 43.96 N +ATOM 5053 CA THR C 349 -47.607 5.832 -70.554 1.00 44.39 C +ATOM 5054 C THR C 349 -46.674 6.144 -69.394 1.00 43.98 C +ATOM 5055 O THR C 349 -46.148 7.258 -69.286 1.00 38.00 O +ATOM 5056 CB THR C 349 -49.060 5.881 -70.095 1.00 43.37 C +ATOM 5057 OG1 THR C 349 -49.910 5.424 -71.154 1.00 40.31 O +ATOM 5058 CG2 THR C 349 -49.450 7.294 -69.696 1.00 45.52 C +ATOM 5059 N GLU C 350 -46.399 5.146 -68.562 1.00 48.31 N +ATOM 5060 CA GLU C 350 -45.626 5.319 -67.344 1.00 46.84 C +ATOM 5061 C GLU C 350 -44.133 5.452 -67.600 1.00 48.88 C +ATOM 5062 O GLU C 350 -43.362 5.542 -66.638 1.00 47.06 O +ATOM 5063 CB GLU C 350 -45.904 4.157 -66.385 1.00 48.43 C +ATOM 5064 CG GLU C 350 -46.300 2.838 -67.056 1.00 53.13 C +ATOM 5065 CD GLU C 350 -47.803 2.699 -67.325 1.00 51.30 C +ATOM 5066 OE1 GLU C 350 -48.307 3.338 -68.272 1.00 56.47 O +ATOM 5067 OE2 GLU C 350 -48.481 1.941 -66.597 1.00 45.12 O +ATOM 5068 N HIS C 351 -43.702 5.444 -68.861 1.00 49.52 N +ATOM 5069 CA HIS C 351 -42.331 5.809 -69.196 1.00 61.57 C +ATOM 5070 C HIS C 351 -42.285 6.893 -70.263 1.00 56.81 C +ATOM 5071 O HIS C 351 -41.266 7.039 -70.948 1.00 53.64 O +ATOM 5072 CB HIS C 351 -41.525 4.591 -69.637 1.00 60.66 C +ATOM 5073 CG HIS C 351 -41.047 3.757 -68.495 1.00 53.71 C +ATOM 5074 ND1 HIS C 351 -41.694 2.611 -68.086 1.00 53.92 N +ATOM 5075 CD2 HIS C 351 -40.004 3.924 -67.649 1.00 47.94 C +ATOM 5076 CE1 HIS C 351 -41.058 2.096 -67.050 1.00 55.89 C +ATOM 5077 NE2 HIS C 351 -40.029 2.875 -66.764 1.00 59.31 N +ATOM 5078 N ALA C 352 -43.358 7.672 -70.386 1.00 52.91 N +ATOM 5079 CA ALA C 352 -43.456 8.658 -71.449 1.00 52.51 C +ATOM 5080 C ALA C 352 -42.315 9.659 -71.370 1.00 51.34 C +ATOM 5081 O ALA C 352 -41.871 10.042 -70.285 1.00 53.01 O +ATOM 5082 CB ALA C 352 -44.797 9.387 -71.376 1.00 49.25 C +ATOM 5083 N LEU C 353 -41.808 10.039 -72.533 1.00 51.09 N +ATOM 5084 CA LEU C 353 -40.773 11.054 -72.633 1.00 60.26 C +ATOM 5085 C LEU C 353 -41.440 12.415 -72.763 1.00 64.98 C +ATOM 5086 O LEU C 353 -42.268 12.624 -73.656 1.00 63.09 O +ATOM 5087 CB LEU C 353 -39.852 10.778 -73.816 1.00 56.10 C +ATOM 5088 CG LEU C 353 -39.190 9.407 -73.764 1.00 57.86 C +ATOM 5089 CD1 LEU C 353 -38.419 9.176 -75.035 1.00 59.34 C +ATOM 5090 CD2 LEU C 353 -38.281 9.320 -72.547 1.00 61.71 C +ATOM 5091 N CYS C 354 -41.124 13.317 -71.841 1.00 62.89 N +ATOM 5092 CA CYS C 354 -41.732 14.635 -71.809 1.00 61.78 C +ATOM 5093 C CYS C 354 -40.653 15.705 -71.794 1.00 69.13 C +ATOM 5094 O CYS C 354 -39.569 15.506 -71.233 1.00 51.55 O +ATOM 5095 CB CYS C 354 -42.620 14.790 -70.593 1.00 56.69 C +ATOM 5096 SG CYS C 354 -43.677 13.381 -70.302 1.00 53.57 S +ATOM 5097 N GLY C 355 -40.945 16.824 -72.458 1.00 78.58 N +ATOM 5098 CA GLY C 355 -40.155 18.027 -72.336 1.00 73.36 C +ATOM 5099 C GLY C 355 -40.768 19.005 -71.342 1.00 64.30 C +ATOM 5100 O GLY C 355 -41.819 18.774 -70.748 1.00 63.51 O +ATOM 5101 N LYS C 356 -40.092 20.139 -71.185 1.00 59.29 N +ATOM 5102 CA LYS C 356 -40.572 21.204 -70.311 1.00 62.33 C +ATOM 5103 C LYS C 356 -40.560 22.512 -71.090 1.00 61.45 C +ATOM 5104 O LYS C 356 -39.568 23.252 -71.072 1.00 64.88 O +ATOM 5105 CB LYS C 356 -39.733 21.292 -69.038 1.00 69.38 C +ATOM 5106 CG LYS C 356 -40.317 22.207 -67.961 1.00 84.89 C +ATOM 5107 CD LYS C 356 -41.788 21.885 -67.679 1.00 76.42 C +ATOM 5108 CE LYS C 356 -42.347 22.725 -66.530 1.00 68.62 C +ATOM 5109 NZ LYS C 356 -42.910 21.885 -65.429 1.00 65.94 N +ATOM 5110 N PRO C 357 -41.652 22.828 -71.801 1.00 66.80 N +ATOM 5111 CA PRO C 357 -42.815 21.949 -71.961 1.00 69.29 C +ATOM 5112 C PRO C 357 -42.807 21.173 -73.275 1.00 69.82 C +ATOM 5113 O PRO C 357 -43.669 20.308 -73.463 1.00 61.68 O +ATOM 5114 CB PRO C 357 -43.987 22.928 -71.931 1.00 64.95 C +ATOM 5115 CG PRO C 357 -43.433 24.152 -72.582 1.00 82.33 C +ATOM 5116 CD PRO C 357 -41.949 24.203 -72.242 1.00 81.64 C +ATOM 5117 N ASP C 358 -41.858 21.478 -74.170 1.00 74.77 N +ATOM 5118 CA ASP C 358 -41.874 20.888 -75.505 1.00 73.49 C +ATOM 5119 C ASP C 358 -40.466 20.825 -76.101 1.00 61.48 C +ATOM 5120 O ASP C 358 -40.275 21.047 -77.300 1.00 64.96 O +ATOM 5121 CB ASP C 358 -42.822 21.652 -76.435 1.00 74.87 C +ATOM 5122 CG ASP C 358 -42.431 23.115 -76.605 1.00 81.81 C +ATOM 5123 OD1 ASP C 358 -41.849 23.691 -75.658 1.00 77.23 O +ATOM 5124 OD2 ASP C 358 -42.736 23.696 -77.674 1.00 89.08 O +ATOM 5125 N GLN C 359 -39.471 20.500 -75.285 1.00 58.31 N +ATOM 5126 CA GLN C 359 -38.131 20.229 -75.795 1.00 66.69 C +ATOM 5127 C GLN C 359 -37.576 19.022 -75.056 1.00 78.51 C +ATOM 5128 O GLN C 359 -37.611 18.985 -73.823 1.00 86.22 O +ATOM 5129 CB GLN C 359 -37.198 21.438 -75.647 1.00 71.96 C +ATOM 5130 CG GLN C 359 -37.605 22.656 -76.478 1.00 70.36 C +ATOM 5131 CD GLN C 359 -36.436 23.595 -76.746 1.00 73.65 C +ATOM 5132 OE1 GLN C 359 -35.628 23.356 -77.644 1.00 71.52 O +ATOM 5133 NE2 GLN C 359 -36.349 24.673 -75.974 1.00 70.52 N +ATOM 5134 N ILE C 360 -37.067 18.039 -75.803 1.00 74.91 N +ATOM 5135 CA ILE C 360 -36.870 16.701 -75.247 1.00 68.73 C +ATOM 5136 C ILE C 360 -35.402 16.282 -75.181 1.00 56.23 C +ATOM 5137 O ILE C 360 -35.033 15.477 -74.318 1.00 55.81 O +ATOM 5138 CB ILE C 360 -37.710 15.670 -76.022 1.00 52.98 C +ATOM 5139 CG1 ILE C 360 -36.821 14.658 -76.738 1.00 50.06 C +ATOM 5140 CG2 ILE C 360 -38.584 16.362 -77.016 1.00 54.28 C +ATOM 5141 CD1 ILE C 360 -37.599 13.577 -77.434 1.00 62.48 C +ATOM 5142 N GLU C 361 -34.561 16.789 -76.092 1.00 50.53 N +ATOM 5143 CA GLU C 361 -33.131 16.462 -76.096 1.00 54.07 C +ATOM 5144 C GLU C 361 -32.895 15.022 -76.547 1.00 59.66 C +ATOM 5145 O GLU C 361 -33.730 14.145 -76.302 1.00 58.90 O +ATOM 5146 CB GLU C 361 -32.515 16.710 -74.704 1.00 48.91 C +ATOM 5147 CG GLU C 361 -31.056 16.296 -74.505 1.00 53.77 C +ATOM 5148 CD GLU C 361 -30.561 16.525 -73.065 1.00 62.08 C +ATOM 5149 OE1 GLU C 361 -29.810 15.670 -72.538 1.00 54.11 O +ATOM 5150 OE2 GLU C 361 -30.900 17.570 -72.465 1.00 65.99 O +ATOM 5151 N GLY C 362 -31.777 14.769 -77.218 1.00 65.44 N +ATOM 5152 CA GLY C 362 -31.475 13.433 -77.696 1.00 59.33 C +ATOM 5153 C GLY C 362 -30.227 13.429 -78.554 1.00 54.90 C +ATOM 5154 O GLY C 362 -29.567 14.455 -78.745 1.00 54.46 O +ATOM 5155 N SER C 363 -29.908 12.238 -79.062 1.00 51.96 N +ATOM 5156 CA SER C 363 -28.725 12.024 -79.883 1.00 50.29 C +ATOM 5157 C SER C 363 -29.112 11.560 -81.283 1.00 50.59 C +ATOM 5158 O SER C 363 -30.102 10.844 -81.476 1.00 45.15 O +ATOM 5159 CB SER C 363 -27.782 11.004 -79.243 1.00 46.63 C +ATOM 5160 OG SER C 363 -28.374 9.720 -79.215 1.00 52.14 O +ATOM 5161 N LEU C 364 -28.312 11.983 -82.260 1.00 47.70 N +ATOM 5162 CA LEU C 364 -28.493 11.646 -83.669 1.00 44.30 C +ATOM 5163 C LEU C 364 -27.267 10.862 -84.132 1.00 52.22 C +ATOM 5164 O LEU C 364 -26.207 11.447 -84.376 1.00 52.64 O +ATOM 5165 CB LEU C 364 -28.689 12.896 -84.523 1.00 45.79 C +ATOM 5166 CG LEU C 364 -30.075 13.531 -84.667 1.00 42.96 C +ATOM 5167 CD1 LEU C 364 -31.079 12.514 -85.126 1.00 38.00 C +ATOM 5168 CD2 LEU C 364 -30.524 14.175 -83.370 1.00 60.95 C +ATOM 5169 N ALA C 365 -27.402 9.542 -84.223 1.00 54.03 N +ATOM 5170 CA ALA C 365 -26.346 8.681 -84.744 1.00 49.21 C +ATOM 5171 C ALA C 365 -26.492 8.579 -86.260 1.00 44.52 C +ATOM 5172 O ALA C 365 -27.566 8.229 -86.758 1.00 40.93 O +ATOM 5173 CB ALA C 365 -26.399 7.301 -84.090 1.00 54.72 C +ATOM 5174 N ALA C 366 -25.426 8.920 -86.985 1.00 48.00 N +ATOM 5175 CA ALA C 366 -25.438 8.891 -88.445 1.00 45.12 C +ATOM 5176 C ALA C 366 -25.767 7.499 -88.976 1.00 43.90 C +ATOM 5177 O ALA C 366 -25.404 6.481 -88.383 1.00 50.53 O +ATOM 5178 CB ALA C 366 -24.082 9.333 -88.990 1.00 46.93 C +ATOM 5179 N PHE C 367 -26.437 7.460 -90.126 1.00 41.10 N +ATOM 5180 CA PHE C 367 -26.921 6.206 -90.690 1.00 42.44 C +ATOM 5181 C PHE C 367 -25.842 5.555 -91.545 1.00 42.24 C +ATOM 5182 O PHE C 367 -25.273 6.195 -92.435 1.00 38.00 O +ATOM 5183 CB PHE C 367 -28.184 6.434 -91.523 1.00 43.64 C +ATOM 5184 CG PHE C 367 -29.329 5.530 -91.153 1.00 42.56 C +ATOM 5185 CD1 PHE C 367 -29.100 4.312 -90.538 1.00 47.88 C +ATOM 5186 CD2 PHE C 367 -30.636 5.904 -91.416 1.00 42.97 C +ATOM 5187 CE1 PHE C 367 -30.156 3.485 -90.196 1.00 64.22 C +ATOM 5188 CE2 PHE C 367 -31.693 5.087 -91.074 1.00 39.12 C +ATOM 5189 CZ PHE C 367 -31.454 3.876 -90.464 1.00 49.32 C +ATOM 5190 N LEU C 368 -25.544 4.288 -91.246 1.00 45.90 N +ATOM 5191 CA LEU C 368 -24.674 3.487 -92.091 1.00 39.34 C +ATOM 5192 C LEU C 368 -25.305 3.306 -93.473 1.00 41.04 C +ATOM 5193 O LEU C 368 -26.524 3.402 -93.623 1.00 44.23 O +ATOM 5194 CB LEU C 368 -24.398 2.137 -91.427 1.00 38.00 C +ATOM 5195 CG LEU C 368 -23.379 2.176 -90.283 1.00 38.00 C +ATOM 5196 CD1 LEU C 368 -23.150 0.798 -89.699 1.00 41.05 C +ATOM 5197 CD2 LEU C 368 -22.057 2.757 -90.757 1.00 38.00 C +ATOM 5198 N PRO C 369 -24.491 3.044 -94.501 1.00 42.77 N +ATOM 5199 CA PRO C 369 -25.029 2.974 -95.865 1.00 39.35 C +ATOM 5200 C PRO C 369 -26.043 1.856 -96.011 1.00 41.76 C +ATOM 5201 O PRO C 369 -26.036 0.880 -95.256 1.00 43.52 O +ATOM 5202 CB PRO C 369 -23.790 2.716 -96.725 1.00 41.61 C +ATOM 5203 CG PRO C 369 -22.833 2.077 -95.809 1.00 48.51 C +ATOM 5204 CD PRO C 369 -23.058 2.705 -94.469 1.00 45.95 C +ATOM 5205 N ASP C 370 -26.925 2.023 -96.998 1.00 43.15 N +ATOM 5206 CA ASP C 370 -28.049 1.113 -97.178 1.00 47.04 C +ATOM 5207 C ASP C 370 -27.573 -0.320 -97.364 1.00 44.85 C +ATOM 5208 O ASP C 370 -26.736 -0.608 -98.224 1.00 40.93 O +ATOM 5209 CB ASP C 370 -28.896 1.550 -98.372 1.00 47.11 C +ATOM 5210 CG ASP C 370 -30.220 0.815 -98.438 1.00 51.80 C +ATOM 5211 OD1 ASP C 370 -30.648 0.298 -97.383 1.00 65.38 O +ATOM 5212 OD2 ASP C 370 -30.849 0.777 -99.517 1.00 42.03 O +ATOM 5213 N LEU C 371 -28.169 -1.231 -96.593 1.00 50.76 N +ATOM 5214 CA LEU C 371 -27.738 -2.621 -96.578 1.00 48.76 C +ATOM 5215 C LEU C 371 -27.830 -3.288 -97.936 1.00 41.69 C +ATOM 5216 O LEU C 371 -27.355 -4.418 -98.077 1.00 45.40 O +ATOM 5217 CB LEU C 371 -28.550 -3.423 -95.564 1.00 51.21 C +ATOM 5218 CG LEU C 371 -28.274 -3.121 -94.092 1.00 50.66 C +ATOM 5219 CD1 LEU C 371 -29.154 -1.988 -93.573 1.00 54.48 C +ATOM 5220 CD2 LEU C 371 -28.429 -4.384 -93.257 1.00 48.63 C +ATOM 5221 N ALA C 372 -28.427 -2.634 -98.929 1.00 38.09 N +ATOM 5222 CA ALA C 372 -28.532 -3.248-100.245 1.00 43.02 C +ATOM 5223 C ALA C 372 -27.171 -3.316-100.927 1.00 45.63 C +ATOM 5224 O ALA C 372 -26.790 -4.358-101.472 1.00 44.80 O +ATOM 5225 CB ALA C 372 -29.536 -2.479-101.100 1.00 43.46 C +ATOM 5226 N LEU C 373 -26.417 -2.216-100.900 1.00 46.48 N +ATOM 5227 CA LEU C 373 -25.091 -2.167-101.503 1.00 49.52 C +ATOM 5228 C LEU C 373 -23.966 -2.212-100.476 1.00 52.59 C +ATOM 5229 O LEU C 373 -22.816 -1.922-100.820 1.00 58.82 O +ATOM 5230 CB LEU C 373 -24.948 -0.922-102.387 1.00 45.14 C +ATOM 5231 CG LEU C 373 -25.653 0.388-102.030 1.00 39.92 C +ATOM 5232 CD1 LEU C 373 -25.271 0.854-100.647 1.00 49.74 C +ATOM 5233 CD2 LEU C 373 -25.322 1.458-103.059 1.00 38.00 C +ATOM 5234 N ALA C 374 -24.269 -2.554 -99.228 1.00 52.04 N +ATOM 5235 CA ALA C 374 -23.271 -2.651 -98.170 1.00 48.49 C +ATOM 5236 C ALA C 374 -23.779 -3.619 -97.102 1.00 51.32 C +ATOM 5237 O ALA C 374 -23.995 -3.256 -95.946 1.00 50.07 O +ATOM 5238 CB ALA C 374 -22.961 -1.272 -97.590 1.00 46.82 C +ATOM 5239 N LYS C 375 -23.995 -4.873 -97.505 1.00 50.73 N +ATOM 5240 CA LYS C 375 -24.469 -5.899 -96.583 1.00 47.63 C +ATOM 5241 C LYS C 375 -23.537 -6.012 -95.382 1.00 45.74 C +ATOM 5242 O LYS C 375 -22.315 -5.904 -95.510 1.00 45.56 O +ATOM 5243 CB LYS C 375 -24.568 -7.254 -97.293 1.00 51.45 C +ATOM 5244 CG LYS C 375 -25.901 -7.554 -97.989 1.00 59.86 C +ATOM 5245 CD LYS C 375 -25.921 -7.063 -99.440 1.00 66.75 C +ATOM 5246 CE LYS C 375 -27.217 -7.450-100.152 1.00 62.87 C +ATOM 5247 NZ LYS C 375 -28.430 -6.924 -99.459 1.00 66.81 N +ATOM 5248 N ARG C 376 -24.119 -6.235 -94.207 1.00 43.96 N +ATOM 5249 CA ARG C 376 -23.355 -6.337 -92.971 1.00 41.19 C +ATOM 5250 C ARG C 376 -23.572 -7.710 -92.358 1.00 42.32 C +ATOM 5251 O ARG C 376 -24.705 -8.071 -92.022 1.00 38.00 O +ATOM 5252 CB ARG C 376 -23.769 -5.253 -91.981 1.00 39.46 C +ATOM 5253 CG ARG C 376 -23.804 -3.881 -92.579 1.00 43.26 C +ATOM 5254 CD ARG C 376 -23.784 -2.843 -91.493 1.00 40.56 C +ATOM 5255 NE ARG C 376 -24.807 -1.838 -91.735 1.00 55.24 N +ATOM 5256 CZ ARG C 376 -26.006 -1.846 -91.164 1.00 53.73 C +ATOM 5257 NH1 ARG C 376 -26.325 -2.813 -90.309 1.00 45.29 N +ATOM 5258 NH2 ARG C 376 -26.880 -0.885 -91.445 1.00 52.98 N +ATOM 5259 N LYS C 377 -22.488 -8.470 -92.211 1.00 45.63 N +ATOM 5260 CA LYS C 377 -22.552 -9.701 -91.442 1.00 47.99 C +ATOM 5261 C LYS C 377 -22.856 -9.374 -89.992 1.00 44.39 C +ATOM 5262 O LYS C 377 -22.542 -8.292 -89.498 1.00 48.28 O +ATOM 5263 CB LYS C 377 -21.230 -10.464 -91.526 1.00 52.65 C +ATOM 5264 CG LYS C 377 -21.305 -11.943 -91.140 1.00 53.68 C +ATOM 5265 CD LYS C 377 -21.937 -12.775 -92.247 1.00 60.86 C +ATOM 5266 CE LYS C 377 -21.442 -14.207 -92.210 1.00 53.29 C +ATOM 5267 NZ LYS C 377 -21.757 -14.844 -90.906 1.00 55.07 N +ATOM 5268 N THR C 378 -23.444 -10.333 -89.291 1.00 48.50 N +ATOM 5269 CA THR C 378 -23.774 -10.148 -87.883 1.00 51.96 C +ATOM 5270 C THR C 378 -23.321 -11.383 -87.119 1.00 51.13 C +ATOM 5271 O THR C 378 -23.878 -12.471 -87.292 1.00 55.60 O +ATOM 5272 CB THR C 378 -25.269 -9.881 -87.695 1.00 48.51 C +ATOM 5273 OG1 THR C 378 -25.628 -10.122 -86.330 1.00 43.07 O +ATOM 5274 CG2 THR C 378 -26.105 -10.758 -88.634 1.00 50.30 C +ATOM 5275 N TRP C 379 -22.322 -11.207 -86.266 1.00 48.60 N +ATOM 5276 CA TRP C 379 -21.686 -12.310 -85.569 1.00 48.56 C +ATOM 5277 C TRP C 379 -22.129 -12.332 -84.116 1.00 50.89 C +ATOM 5278 O TRP C 379 -22.417 -11.291 -83.516 1.00 50.23 O +ATOM 5279 CB TRP C 379 -20.166 -12.200 -85.636 1.00 49.38 C +ATOM 5280 CG TRP C 379 -19.625 -12.026 -87.011 1.00 48.23 C +ATOM 5281 CD1 TRP C 379 -19.682 -10.903 -87.771 1.00 50.15 C +ATOM 5282 CD2 TRP C 379 -18.918 -12.998 -87.783 1.00 49.49 C +ATOM 5283 NE1 TRP C 379 -19.062 -11.113 -88.976 1.00 52.49 N +ATOM 5284 CE2 TRP C 379 -18.584 -12.395 -89.008 1.00 51.36 C +ATOM 5285 CE3 TRP C 379 -18.544 -14.324 -87.561 1.00 57.66 C +ATOM 5286 CZ2 TRP C 379 -17.893 -13.069 -90.008 1.00 55.57 C +ATOM 5287 CZ3 TRP C 379 -17.857 -14.992 -88.554 1.00 65.42 C +ATOM 5288 CH2 TRP C 379 -17.540 -14.365 -89.763 1.00 62.97 C +ATOM 5289 N ARG C 380 -22.176 -13.537 -83.562 1.00 49.99 N +ATOM 5290 CA ARG C 380 -22.581 -13.745 -82.181 1.00 51.44 C +ATOM 5291 C ARG C 380 -21.337 -13.748 -81.300 1.00 50.34 C +ATOM 5292 O ARG C 380 -20.374 -14.477 -81.577 1.00 45.62 O +ATOM 5293 CB ARG C 380 -23.369 -15.050 -82.050 1.00 59.14 C +ATOM 5294 CG ARG C 380 -23.673 -15.476 -80.621 1.00 66.82 C +ATOM 5295 CD ARG C 380 -24.272 -16.881 -80.563 1.00 75.06 C +ATOM 5296 NE ARG C 380 -25.244 -17.021 -79.478 1.00 86.56 N +ATOM 5297 CZ ARG C 380 -24.976 -17.594 -78.306 1.00 80.72 C +ATOM 5298 NH1 ARG C 380 -23.762 -18.076 -78.069 1.00 77.56 N +ATOM 5299 NH2 ARG C 380 -25.919 -17.683 -77.372 1.00 76.01 N +ATOM 5300 N ASN C 381 -21.334 -12.890 -80.287 1.00 50.78 N +ATOM 5301 CA ASN C 381 -20.198 -12.801 -79.381 1.00 45.13 C +ATOM 5302 C ASN C 381 -20.067 -14.103 -78.597 1.00 45.01 C +ATOM 5303 O ASN C 381 -21.053 -14.574 -78.014 1.00 44.46 O +ATOM 5304 CB ASN C 381 -20.375 -11.618 -78.430 1.00 42.06 C +ATOM 5305 CG ASN C 381 -19.118 -11.301 -77.635 1.00 39.57 C +ATOM 5306 OD1 ASN C 381 -18.298 -12.173 -77.360 1.00 41.34 O +ATOM 5307 ND2 ASN C 381 -18.968 -10.041 -77.258 1.00 39.40 N +ATOM 5308 N PRO C 382 -18.879 -14.707 -78.547 1.00 40.58 N +ATOM 5309 CA PRO C 382 -18.721 -15.918 -77.731 1.00 43.14 C +ATOM 5310 C PRO C 382 -18.840 -15.669 -76.238 1.00 47.70 C +ATOM 5311 O PRO C 382 -19.062 -16.629 -75.491 1.00 58.21 O +ATOM 5312 CB PRO C 382 -17.320 -16.414 -78.109 1.00 41.27 C +ATOM 5313 CG PRO C 382 -16.625 -15.216 -78.640 1.00 38.00 C +ATOM 5314 CD PRO C 382 -17.674 -14.420 -79.341 1.00 38.00 C +ATOM 5315 N TRP C 383 -18.709 -14.424 -75.777 1.00 44.23 N +ATOM 5316 CA TRP C 383 -18.952 -14.078 -74.383 1.00 42.70 C +ATOM 5317 C TRP C 383 -20.323 -13.453 -74.182 1.00 43.64 C +ATOM 5318 O TRP C 383 -20.527 -12.710 -73.218 1.00 50.11 O +ATOM 5319 CB TRP C 383 -17.857 -13.149 -73.863 1.00 41.80 C +ATOM 5320 CG TRP C 383 -16.532 -13.817 -73.769 1.00 44.20 C +ATOM 5321 CD1 TRP C 383 -16.056 -14.542 -72.719 1.00 47.85 C +ATOM 5322 CD2 TRP C 383 -15.508 -13.843 -74.775 1.00 46.61 C +ATOM 5323 NE1 TRP C 383 -14.795 -15.012 -73.003 1.00 53.24 N +ATOM 5324 CE2 TRP C 383 -14.436 -14.596 -74.259 1.00 46.59 C +ATOM 5325 CE3 TRP C 383 -15.393 -13.299 -76.057 1.00 44.46 C +ATOM 5326 CZ2 TRP C 383 -13.266 -14.820 -74.982 1.00 43.72 C +ATOM 5327 CZ3 TRP C 383 -14.232 -13.521 -76.771 1.00 40.69 C +ATOM 5328 CH2 TRP C 383 -13.185 -14.274 -76.232 1.00 42.28 C +ATOM 5329 N ARG C 384 -21.261 -13.737 -75.078 1.00 43.66 N +ATOM 5330 CA ARG C 384 -22.603 -13.186 -74.966 1.00 50.26 C +ATOM 5331 C ARG C 384 -23.280 -13.693 -73.701 1.00 48.79 C +ATOM 5332 O ARG C 384 -23.318 -14.897 -73.444 1.00 57.04 O +ATOM 5333 CB ARG C 384 -23.426 -13.572 -76.192 1.00 54.76 C +ATOM 5334 CG ARG C 384 -24.900 -13.244 -76.085 1.00 57.62 C +ATOM 5335 CD ARG C 384 -25.691 -13.998 -77.134 1.00 64.23 C +ATOM 5336 NE ARG C 384 -27.016 -13.420 -77.352 1.00 72.08 N +ATOM 5337 CZ ARG C 384 -28.153 -13.950 -76.913 1.00 65.14 C +ATOM 5338 NH1 ARG C 384 -28.137 -15.086 -76.228 1.00 57.94 N +ATOM 5339 NH2 ARG C 384 -29.308 -13.342 -77.168 1.00 57.85 N +ATOM 5340 N ARG C 385 -23.789 -12.767 -72.896 1.00 47.17 N +ATOM 5341 CA ARG C 385 -24.501 -13.155 -71.687 1.00 52.77 C +ATOM 5342 C ARG C 385 -25.739 -13.978 -72.031 1.00 52.20 C +ATOM 5343 O ARG C 385 -26.314 -13.854 -73.115 1.00 52.75 O +ATOM 5344 CB ARG C 385 -24.873 -11.919 -70.872 1.00 59.23 C +ATOM 5345 CG ARG C 385 -23.673 -11.294 -70.175 1.00 59.47 C +ATOM 5346 CD ARG C 385 -23.930 -9.870 -69.743 1.00 55.43 C +ATOM 5347 NE ARG C 385 -22.688 -9.105 -69.654 1.00 64.23 N +ATOM 5348 CZ ARG C 385 -21.847 -9.134 -68.623 1.00 62.46 C +ATOM 5349 NH1 ARG C 385 -22.096 -9.901 -67.568 1.00 60.20 N +ATOM 5350 NH2 ARG C 385 -20.749 -8.390 -68.653 1.00 58.23 N +ATOM 5351 N SER C 386 -26.130 -14.853 -71.099 1.00 51.04 N +ATOM 5352 CA SER C 386 -27.248 -15.759 -71.350 1.00 59.50 C +ATOM 5353 C SER C 386 -28.567 -15.029 -71.539 1.00 59.32 C +ATOM 5354 O SER C 386 -29.498 -15.602 -72.114 1.00 68.02 O +ATOM 5355 CB SER C 386 -27.396 -16.753 -70.198 1.00 69.68 C +ATOM 5356 OG SER C 386 -27.740 -16.087 -68.994 1.00 67.33 O +ATOM 5357 N TYR C 387 -28.667 -13.785 -71.075 1.00 57.94 N +ATOM 5358 CA TYR C 387 -29.895 -12.997 -71.173 1.00 62.91 C +ATOM 5359 C TYR C 387 -31.085 -13.771 -70.611 1.00 65.86 C +ATOM 5360 O TYR C 387 -32.151 -13.872 -71.225 1.00 58.60 O +ATOM 5361 CB TYR C 387 -30.145 -12.554 -72.614 1.00 59.73 C +ATOM 5362 CG TYR C 387 -29.115 -11.560 -73.100 1.00 60.46 C +ATOM 5363 CD1 TYR C 387 -28.816 -10.420 -72.366 1.00 60.00 C +ATOM 5364 CD2 TYR C 387 -28.420 -11.777 -74.277 1.00 62.83 C +ATOM 5365 CE1 TYR C 387 -27.865 -9.520 -72.799 1.00 57.50 C +ATOM 5366 CE2 TYR C 387 -27.473 -10.885 -74.716 1.00 63.30 C +ATOM 5367 CZ TYR C 387 -27.196 -9.759 -73.979 1.00 59.30 C +ATOM 5368 OH TYR C 387 -26.244 -8.875 -74.435 1.00 63.53 O +ATOM 5369 N HIS C 388 -30.879 -14.319 -69.415 1.00 69.36 N +ATOM 5370 CA HIS C 388 -31.879 -15.110 -68.709 1.00 73.47 C +ATOM 5371 C HIS C 388 -31.500 -15.140 -67.238 1.00 73.74 C +ATOM 5372 O HIS C 388 -30.350 -15.438 -66.901 1.00 72.65 O +ATOM 5373 CB HIS C 388 -31.970 -16.535 -69.267 1.00 73.81 C +ATOM 5374 CG HIS C 388 -32.977 -16.691 -70.363 1.00 79.37 C +ATOM 5375 ND1 HIS C 388 -34.097 -15.893 -70.459 1.00 87.43 N +ATOM 5376 CD2 HIS C 388 -33.034 -17.546 -71.412 1.00 74.63 C +ATOM 5377 CE1 HIS C 388 -34.799 -16.248 -71.521 1.00 89.36 C +ATOM 5378 NE2 HIS C 388 -34.176 -17.249 -72.116 1.00 83.19 N +ATOM 5379 N LYS C 389 -32.444 -14.770 -66.375 1.00 79.16 N +ATOM 5380 CA LYS C 389 -32.209 -14.856 -64.940 1.00 78.77 C +ATOM 5381 C LYS C 389 -31.994 -16.311 -64.528 1.00 88.79 C +ATOM 5382 O LYS C 389 -32.469 -17.243 -65.188 1.00 87.78 O +ATOM 5383 CB LYS C 389 -33.376 -14.241 -64.161 1.00 74.97 C +ATOM 5384 CG LYS C 389 -34.619 -13.918 -64.997 1.00 80.02 C +ATOM 5385 CD LYS C 389 -35.769 -13.418 -64.118 1.00 66.71 C +ATOM 5386 CE LYS C 389 -36.900 -12.821 -64.945 1.00 64.09 C +ATOM 5387 NZ LYS C 389 -36.469 -11.587 -65.660 1.00 65.14 N +ATOM 5388 N ARG C 390 -31.254 -16.495 -63.427 1.00 90.08 N +ATOM 5389 CA ARG C 390 -30.938 -17.803 -62.850 1.00 86.03 C +ATOM 5390 C ARG C 390 -29.933 -18.559 -63.715 1.00 82.73 C +ATOM 5391 O ARG C 390 -28.868 -18.960 -63.233 1.00 83.85 O +ATOM 5392 CB ARG C 390 -32.206 -18.645 -62.645 1.00 84.88 C +ATOM 5393 CG ARG C 390 -33.199 -18.083 -61.628 1.00 85.06 C +ATOM 5394 CD ARG C 390 -34.585 -17.982 -62.251 1.00 86.16 C +ATOM 5395 NE ARG C 390 -35.573 -17.388 -61.354 1.00 77.51 N +ATOM 5396 CZ ARG C 390 -36.790 -17.006 -61.733 1.00 70.50 C +ATOM 5397 NH1 ARG C 390 -37.172 -17.144 -62.996 1.00 71.33 N +ATOM 5398 NH2 ARG C 390 -37.627 -16.480 -60.851 1.00 61.73 N +ATOM 5399 N LYS C 391 -30.271 -18.768 -64.984 1.00 79.83 N +ATOM 5400 CA LYS C 391 -29.465 -19.588 -65.883 1.00 72.57 C +ATOM 5401 C LYS C 391 -28.127 -18.922 -66.197 1.00 71.94 C +ATOM 5402 O LYS C 391 -28.084 -17.794 -66.697 1.00 74.36 O +ATOM 5403 CB LYS C 391 -30.260 -19.839 -67.160 1.00 66.49 C +ATOM 5404 CG LYS C 391 -31.737 -20.069 -66.855 1.00 77.13 C +ATOM 5405 CD LYS C 391 -32.651 -19.775 -68.033 1.00 87.51 C +ATOM 5406 CE LYS C 391 -33.882 -18.973 -67.591 1.00 85.42 C +ATOM 5407 NZ LYS C 391 -34.549 -19.492 -66.358 1.00 79.44 N +ATOM 5408 N LYS C 392 -27.034 -19.640 -65.939 1.00 69.49 N +ATOM 5409 CA LYS C 392 -25.686 -19.106 -66.110 1.00 69.83 C +ATOM 5410 C LYS C 392 -25.271 -19.146 -67.584 1.00 67.39 C +ATOM 5411 O LYS C 392 -26.078 -19.397 -68.484 1.00 64.84 O +ATOM 5412 CB LYS C 392 -24.704 -19.876 -65.230 1.00 72.71 C +ATOM 5413 CG LYS C 392 -24.016 -19.044 -64.157 1.00 75.55 C +ATOM 5414 CD LYS C 392 -22.881 -19.827 -63.495 1.00 88.95 C +ATOM 5415 CE LYS C 392 -23.410 -20.949 -62.603 1.00 97.92 C +ATOM 5416 NZ LYS C 392 -22.338 -21.648 -61.826 1.00 88.96 N +ATOM 5417 N ALA C 393 -23.981 -18.922 -67.840 1.00 65.91 N +ATOM 5418 CA ALA C 393 -23.440 -18.870 -69.191 1.00 59.61 C +ATOM 5419 C ALA C 393 -22.145 -19.666 -69.246 1.00 58.27 C +ATOM 5420 O ALA C 393 -21.501 -19.909 -68.225 1.00 66.95 O +ATOM 5421 CB ALA C 393 -23.187 -17.427 -69.642 1.00 61.62 C +ATOM 5422 N GLU C 394 -21.767 -20.066 -70.463 1.00 58.15 N +ATOM 5423 CA GLU C 394 -20.616 -20.949 -70.631 1.00 62.82 C +ATOM 5424 C GLU C 394 -19.335 -20.291 -70.132 1.00 64.09 C +ATOM 5425 O GLU C 394 -18.588 -20.884 -69.344 1.00 65.03 O +ATOM 5426 CB GLU C 394 -20.478 -21.367 -72.097 1.00 63.46 C +ATOM 5427 CG GLU C 394 -20.521 -22.882 -72.317 1.00 63.51 C +ATOM 5428 CD GLU C 394 -19.250 -23.590 -71.869 1.00 70.40 C +ATOM 5429 OE1 GLU C 394 -18.193 -23.372 -72.496 1.00 66.54 O +ATOM 5430 OE2 GLU C 394 -19.308 -24.366 -70.889 1.00 81.02 O +ATOM 5431 N TRP C 395 -19.061 -19.063 -70.583 1.00 66.07 N +ATOM 5432 CA TRP C 395 -17.838 -18.358 -70.199 1.00 66.24 C +ATOM 5433 C TRP C 395 -17.780 -18.045 -68.705 1.00 58.03 C +ATOM 5434 O TRP C 395 -16.726 -17.623 -68.215 1.00 50.48 O +ATOM 5435 CB TRP C 395 -17.690 -17.077 -71.036 1.00 61.86 C +ATOM 5436 CG TRP C 395 -18.888 -16.160 -70.991 1.00 63.04 C +ATOM 5437 CD1 TRP C 395 -20.067 -16.312 -71.666 1.00 56.71 C +ATOM 5438 CD2 TRP C 395 -19.014 -14.949 -70.234 1.00 62.32 C +ATOM 5439 NE1 TRP C 395 -20.921 -15.276 -71.367 1.00 53.96 N +ATOM 5440 CE2 TRP C 395 -20.298 -14.427 -70.490 1.00 57.30 C +ATOM 5441 CE3 TRP C 395 -18.169 -14.260 -69.360 1.00 60.17 C +ATOM 5442 CZ2 TRP C 395 -20.753 -13.247 -69.905 1.00 58.18 C +ATOM 5443 CZ3 TRP C 395 -18.623 -13.090 -68.780 1.00 55.39 C +ATOM 5444 CH2 TRP C 395 -19.902 -12.595 -69.055 1.00 55.53 C +ATOM 5445 N GLU C 396 -18.874 -18.247 -67.977 1.00 55.26 N +ATOM 5446 CA GLU C 396 -18.927 -18.022 -66.541 1.00 58.79 C +ATOM 5447 C GLU C 396 -18.623 -19.280 -65.734 1.00 62.22 C +ATOM 5448 O GLU C 396 -18.783 -19.272 -64.509 1.00 54.31 O +ATOM 5449 CB GLU C 396 -20.305 -17.488 -66.150 1.00 67.74 C +ATOM 5450 CG GLU C 396 -20.629 -16.118 -66.709 1.00 66.99 C +ATOM 5451 CD GLU C 396 -21.984 -15.617 -66.248 1.00 74.22 C +ATOM 5452 OE1 GLU C 396 -22.766 -16.426 -65.703 1.00 67.95 O +ATOM 5453 OE2 GLU C 396 -22.254 -14.406 -66.403 1.00 77.44 O +ATOM 5454 N VAL C 397 -18.224 -20.366 -66.393 1.00 67.91 N +ATOM 5455 CA VAL C 397 -17.878 -21.600 -65.693 1.00 67.61 C +ATOM 5456 C VAL C 397 -16.599 -22.247 -66.205 1.00 62.95 C +ATOM 5457 O VAL C 397 -15.949 -22.998 -65.453 1.00 59.77 O +ATOM 5458 CB VAL C 397 -19.055 -22.600 -65.758 1.00 70.70 C +ATOM 5459 CG1 VAL C 397 -19.155 -23.221 -67.148 1.00 71.77 C +ATOM 5460 CG2 VAL C 397 -18.918 -23.674 -64.678 1.00 69.08 C +ATOM 5461 N ASP C 398 -16.170 -21.987 -67.438 1.00 58.08 N +ATOM 5462 CA ASP C 398 -14.931 -22.552 -67.958 1.00 60.06 C +ATOM 5463 C ASP C 398 -13.877 -21.462 -67.979 1.00 64.84 C +ATOM 5464 O ASP C 398 -13.950 -20.563 -68.830 1.00 71.68 O +ATOM 5465 CB ASP C 398 -15.130 -23.113 -69.368 1.00 66.69 C +ATOM 5466 CG ASP C 398 -13.911 -23.886 -69.869 1.00 80.45 C +ATOM 5467 OD1 ASP C 398 -12.784 -23.348 -69.808 1.00 76.16 O +ATOM 5468 OD2 ASP C 398 -14.081 -25.027 -70.351 1.00 86.96 O +ATOM 5469 N PRO C 399 -12.863 -21.511 -67.113 1.00 66.34 N +ATOM 5470 CA PRO C 399 -11.845 -20.451 -67.118 1.00 71.14 C +ATOM 5471 C PRO C 399 -10.916 -20.526 -68.310 1.00 76.48 C +ATOM 5472 O PRO C 399 -10.167 -19.571 -68.551 1.00 81.25 O +ATOM 5473 CB PRO C 399 -11.090 -20.683 -65.806 1.00 64.77 C +ATOM 5474 CG PRO C 399 -11.218 -22.144 -65.575 1.00 79.24 C +ATOM 5475 CD PRO C 399 -12.565 -22.559 -66.124 1.00 70.84 C +ATOM 5476 N ASP C 400 -10.929 -21.633 -69.050 1.00 72.23 N +ATOM 5477 CA ASP C 400 -10.123 -21.799 -70.251 1.00 79.73 C +ATOM 5478 C ASP C 400 -10.944 -21.612 -71.523 1.00 78.25 C +ATOM 5479 O ASP C 400 -10.542 -22.091 -72.588 1.00 81.68 O +ATOM 5480 CB ASP C 400 -9.464 -23.176 -70.237 1.00 80.89 C +ATOM 5481 CG ASP C 400 -8.653 -23.416 -68.976 1.00 92.70 C +ATOM 5482 OD1 ASP C 400 -8.239 -22.431 -68.324 1.00 96.42 O +ATOM 5483 OD2 ASP C 400 -8.463 -24.591 -68.609 1.00 98.92 O +ATOM 5484 N TYR C 401 -12.095 -20.941 -71.415 1.00 70.56 N +ATOM 5485 CA TYR C 401 -12.992 -20.728 -72.548 1.00 66.30 C +ATOM 5486 C TYR C 401 -12.239 -20.261 -73.790 1.00 65.84 C +ATOM 5487 O TYR C 401 -12.460 -20.777 -74.892 1.00 63.44 O +ATOM 5488 CB TYR C 401 -14.066 -19.712 -72.152 1.00 67.43 C +ATOM 5489 CG TYR C 401 -15.202 -19.531 -73.136 1.00 67.08 C +ATOM 5490 CD1 TYR C 401 -15.019 -18.843 -74.330 1.00 64.52 C +ATOM 5491 CD2 TYR C 401 -16.469 -20.029 -72.855 1.00 59.95 C +ATOM 5492 CE1 TYR C 401 -16.058 -18.675 -75.223 1.00 52.34 C +ATOM 5493 CE2 TYR C 401 -17.514 -19.858 -73.738 1.00 53.52 C +ATOM 5494 CZ TYR C 401 -17.300 -19.182 -74.920 1.00 48.17 C +ATOM 5495 OH TYR C 401 -18.332 -19.009 -75.806 1.00 45.25 O +ATOM 5496 N CYS C 402 -11.345 -19.279 -73.630 1.00 72.05 N +ATOM 5497 CA CYS C 402 -10.664 -18.702 -74.786 1.00 76.97 C +ATOM 5498 C CYS C 402 -9.824 -19.736 -75.524 1.00 82.50 C +ATOM 5499 O CYS C 402 -9.684 -19.659 -76.750 1.00 84.17 O +ATOM 5500 CB CYS C 402 -9.786 -17.524 -74.351 1.00 78.94 C +ATOM 5501 SG CYS C 402 -8.919 -16.678 -75.720 1.00 87.37 S +ATOM 5502 N ASP C 403 -9.283 -20.726 -74.807 1.00 80.02 N +ATOM 5503 CA ASP C 403 -8.492 -21.764 -75.457 1.00 74.10 C +ATOM 5504 C ASP C 403 -9.341 -22.648 -76.354 1.00 76.70 C +ATOM 5505 O ASP C 403 -8.802 -23.304 -77.250 1.00 77.08 O +ATOM 5506 CB ASP C 403 -7.785 -22.620 -74.410 1.00 72.19 C +ATOM 5507 CG ASP C 403 -6.956 -21.793 -73.451 1.00 86.54 C +ATOM 5508 OD1 ASP C 403 -6.619 -20.640 -73.798 1.00 83.93 O +ATOM 5509 OD2 ASP C 403 -6.639 -22.302 -72.352 1.00 88.03 O +ATOM 5510 N GLU C 404 -10.655 -22.660 -76.145 1.00 75.59 N +ATOM 5511 CA GLU C 404 -11.563 -23.358 -77.042 1.00 71.39 C +ATOM 5512 C GLU C 404 -12.085 -22.445 -78.133 1.00 69.91 C +ATOM 5513 O GLU C 404 -12.323 -22.898 -79.257 1.00 74.97 O +ATOM 5514 CB GLU C 404 -12.738 -23.939 -76.250 1.00 69.93 C +ATOM 5515 CG GLU C 404 -13.351 -25.185 -76.865 1.00 77.26 C +ATOM 5516 CD GLU C 404 -14.438 -25.794 -75.995 1.00 84.61 C +ATOM 5517 OE1 GLU C 404 -15.590 -25.313 -76.052 1.00 83.98 O +ATOM 5518 OE2 GLU C 404 -14.138 -26.760 -75.258 1.00 77.72 O +ATOM 5519 N VAL C 405 -12.226 -21.153 -77.836 1.00 68.00 N +ATOM 5520 CA VAL C 405 -12.752 -20.219 -78.823 1.00 68.83 C +ATOM 5521 C VAL C 405 -11.681 -19.735 -79.783 1.00 68.19 C +ATOM 5522 O VAL C 405 -12.012 -19.157 -80.824 1.00 78.90 O +ATOM 5523 CB VAL C 405 -13.429 -19.032 -78.114 1.00 67.49 C +ATOM 5524 CG1 VAL C 405 -12.416 -17.941 -77.794 1.00 68.11 C +ATOM 5525 CG2 VAL C 405 -14.588 -18.499 -78.939 1.00 59.91 C +ATOM 5526 N LYS C 406 -10.409 -19.976 -79.494 1.00 62.17 N +ATOM 5527 CA LYS C 406 -9.373 -19.655 -80.460 1.00 65.16 C +ATOM 5528 C LYS C 406 -9.134 -20.795 -81.438 1.00 68.51 C +ATOM 5529 O LYS C 406 -8.169 -20.753 -82.210 1.00 68.81 O +ATOM 5530 CB LYS C 406 -8.073 -19.276 -79.744 1.00 71.42 C +ATOM 5531 CG LYS C 406 -7.420 -20.400 -78.977 1.00 76.98 C +ATOM 5532 CD LYS C 406 -6.104 -19.943 -78.363 1.00 77.65 C +ATOM 5533 CE LYS C 406 -6.316 -18.777 -77.398 1.00 75.92 C +ATOM 5534 NZ LYS C 406 -5.124 -17.886 -77.276 1.00 66.94 N +ATOM 5535 N GLN C 407 -10.017 -21.788 -81.454 1.00 66.78 N +ATOM 5536 CA GLN C 407 -9.944 -22.869 -82.420 1.00 74.67 C +ATOM 5537 C GLN C 407 -11.040 -22.798 -83.472 1.00 80.00 C +ATOM 5538 O GLN C 407 -10.960 -23.517 -84.475 1.00 88.30 O +ATOM 5539 CB GLN C 407 -10.019 -24.226 -81.702 1.00 79.65 C +ATOM 5540 CG GLN C 407 -9.208 -25.325 -82.365 1.00 87.60 C +ATOM 5541 CD GLN C 407 -7.985 -25.715 -81.557 1.00 83.22 C +ATOM 5542 OE1 GLN C 407 -7.855 -25.341 -80.388 1.00 74.00 O +ATOM 5543 NE2 GLN C 407 -7.080 -26.473 -82.175 1.00 76.47 N +ATOM 5544 N THR C 408 -12.049 -21.947 -83.275 1.00 77.14 N +ATOM 5545 CA THR C 408 -13.140 -21.801 -84.226 1.00 84.07 C +ATOM 5546 C THR C 408 -12.639 -21.242 -85.563 1.00 75.89 C +ATOM 5547 O THR C 408 -11.589 -20.595 -85.625 1.00 71.38 O +ATOM 5548 CB THR C 408 -14.219 -20.906 -83.624 1.00 75.49 C +ATOM 5549 OG1 THR C 408 -13.681 -20.244 -82.475 1.00 70.08 O +ATOM 5550 CG2 THR C 408 -15.406 -21.747 -83.192 1.00 75.79 C +ATOM 5551 N PRO C 409 -13.392 -21.466 -86.642 1.00 73.14 N +ATOM 5552 CA PRO C 409 -12.921 -21.073 -87.984 1.00 81.84 C +ATOM 5553 C PRO C 409 -12.572 -19.597 -88.098 1.00 87.74 C +ATOM 5554 O PRO C 409 -11.527 -19.274 -88.685 1.00 87.55 O +ATOM 5555 CB PRO C 409 -14.099 -21.444 -88.906 1.00 85.19 C +ATOM 5556 CG PRO C 409 -15.239 -21.825 -87.993 1.00 83.38 C +ATOM 5557 CD PRO C 409 -14.605 -22.300 -86.726 1.00 72.53 C +ATOM 5558 N PRO C 410 -13.362 -18.666 -87.555 1.00 82.35 N +ATOM 5559 CA PRO C 410 -13.033 -17.250 -87.784 1.00 68.14 C +ATOM 5560 C PRO C 410 -12.197 -16.587 -86.698 1.00 63.21 C +ATOM 5561 O PRO C 410 -11.779 -15.444 -86.906 1.00 57.07 O +ATOM 5562 CB PRO C 410 -14.425 -16.610 -87.845 1.00 50.18 C +ATOM 5563 CG PRO C 410 -15.279 -17.463 -86.943 1.00 50.16 C +ATOM 5564 CD PRO C 410 -14.550 -18.757 -86.682 1.00 64.10 C +ATOM 5565 N TYR C 411 -11.885 -17.271 -85.598 1.00 63.70 N +ATOM 5566 CA TYR C 411 -11.162 -16.655 -84.496 1.00 60.46 C +ATOM 5567 C TYR C 411 -9.733 -17.158 -84.378 1.00 60.88 C +ATOM 5568 O TYR C 411 -9.028 -16.762 -83.444 1.00 60.23 O +ATOM 5569 CB TYR C 411 -11.888 -16.893 -83.167 1.00 51.30 C +ATOM 5570 CG TYR C 411 -13.215 -16.182 -82.998 1.00 46.74 C +ATOM 5571 CD1 TYR C 411 -14.005 -15.846 -84.089 1.00 53.12 C +ATOM 5572 CD2 TYR C 411 -13.690 -15.878 -81.738 1.00 48.60 C +ATOM 5573 CE1 TYR C 411 -15.220 -15.215 -83.926 1.00 48.16 C +ATOM 5574 CE2 TYR C 411 -14.902 -15.253 -81.567 1.00 47.95 C +ATOM 5575 CZ TYR C 411 -15.664 -14.922 -82.660 1.00 42.94 C +ATOM 5576 OH TYR C 411 -16.876 -14.299 -82.478 1.00 44.16 O +ATOM 5577 N ASP C 412 -9.280 -18.000 -85.301 1.00 61.90 N +ATOM 5578 CA ASP C 412 -7.887 -18.418 -85.364 1.00 59.34 C +ATOM 5579 C ASP C 412 -7.217 -17.852 -86.615 1.00 65.31 C +ATOM 5580 O ASP C 412 -6.309 -18.461 -87.183 1.00 67.61 O +ATOM 5581 CB ASP C 412 -7.770 -19.944 -85.302 1.00 62.07 C +ATOM 5582 CG ASP C 412 -8.388 -20.632 -86.506 1.00 81.66 C +ATOM 5583 OD1 ASP C 412 -9.284 -20.033 -87.141 1.00 79.89 O +ATOM 5584 OD2 ASP C 412 -8.000 -21.783 -86.804 1.00 89.51 O +ATOM 5585 N ARG C 413 -7.671 -16.679 -87.040 1.00 67.06 N +ATOM 5586 CA ARG C 413 -7.077 -15.928 -88.138 1.00 64.36 C +ATOM 5587 C ARG C 413 -7.197 -14.458 -87.759 1.00 72.58 C +ATOM 5588 O ARG C 413 -7.267 -14.104 -86.578 1.00 77.95 O +ATOM 5589 CB ARG C 413 -7.753 -16.279 -89.476 1.00 60.57 C +ATOM 5590 CG ARG C 413 -6.798 -16.744 -90.550 1.00 58.40 C +ATOM 5591 CD ARG C 413 -7.461 -17.787 -91.425 1.00 72.41 C +ATOM 5592 NE ARG C 413 -6.499 -18.487 -92.273 1.00 92.12 N +ATOM 5593 CZ ARG C 413 -6.756 -19.619 -92.924 1.00 95.47 C +ATOM 5594 NH1 ARG C 413 -7.951 -20.195 -92.827 1.00 89.59 N +ATOM 5595 NH2 ARG C 413 -5.811 -20.181 -93.669 1.00 90.79 N +ATOM 5596 N GLY C 414 -7.206 -13.577 -88.755 1.00 72.84 N +ATOM 5597 CA GLY C 414 -7.280 -12.164 -88.422 1.00 76.90 C +ATOM 5598 C GLY C 414 -6.053 -11.695 -87.635 1.00 80.01 C +ATOM 5599 O GLY C 414 -5.042 -12.396 -87.569 1.00 78.40 O +ATOM 5600 N THR C 415 -6.126 -10.501 -87.015 1.00 72.64 N +ATOM 5601 CA THR C 415 -7.168 -9.437 -86.964 1.00 67.26 C +ATOM 5602 C THR C 415 -8.344 -9.751 -86.040 1.00 64.33 C +ATOM 5603 O THR C 415 -8.644 -8.958 -85.151 1.00 66.83 O +ATOM 5604 CB THR C 415 -7.743 -9.030 -88.356 1.00 75.70 C +ATOM 5605 OG1 THR C 415 -6.704 -9.068 -89.342 1.00 83.45 O +ATOM 5606 CG2 THR C 415 -8.317 -7.621 -88.293 1.00 67.53 C +ATOM 5607 N ARG C 416 -9.003 -10.890 -86.215 1.00 62.60 N +ATOM 5608 CA ARG C 416 -10.036 -11.240 -85.259 1.00 56.66 C +ATOM 5609 C ARG C 416 -9.391 -11.592 -83.919 1.00 59.27 C +ATOM 5610 O ARG C 416 -8.163 -11.652 -83.792 1.00 58.64 O +ATOM 5611 CB ARG C 416 -10.895 -12.384 -85.787 1.00 56.85 C +ATOM 5612 CG ARG C 416 -12.259 -12.460 -85.124 1.00 56.77 C +ATOM 5613 CD ARG C 416 -12.998 -11.140 -85.224 1.00 53.53 C +ATOM 5614 NE ARG C 416 -14.158 -11.257 -86.103 1.00 53.30 N +ATOM 5615 CZ ARG C 416 -14.183 -10.855 -87.370 1.00 56.90 C +ATOM 5616 NH1 ARG C 416 -13.107 -10.291 -87.910 1.00 57.93 N +ATOM 5617 NH2 ARG C 416 -15.286 -11.013 -88.096 1.00 49.19 N +ATOM 5618 N LEU C 417 -10.238 -11.820 -82.909 1.00 62.09 N +ATOM 5619 CA LEU C 417 -9.836 -11.888 -81.503 1.00 64.30 C +ATOM 5620 C LEU C 417 -9.260 -10.547 -81.075 1.00 61.56 C +ATOM 5621 O LEU C 417 -9.756 -9.918 -80.135 1.00 57.83 O +ATOM 5622 CB LEU C 417 -8.814 -13.000 -81.239 1.00 64.27 C +ATOM 5623 CG LEU C 417 -9.267 -14.346 -80.671 1.00 58.08 C +ATOM 5624 CD1 LEU C 417 -8.072 -15.277 -80.586 1.00 58.80 C +ATOM 5625 CD2 LEU C 417 -9.925 -14.187 -79.311 1.00 42.35 C +ATOM 5626 N LEU C 418 -8.206 -10.117 -81.771 1.00 60.45 N +ATOM 5627 CA LEU C 418 -7.642 -8.792 -81.548 1.00 62.95 C +ATOM 5628 C LEU C 418 -8.710 -7.719 -81.712 1.00 66.07 C +ATOM 5629 O LEU C 418 -8.787 -6.775 -80.917 1.00 69.22 O +ATOM 5630 CB LEU C 418 -6.485 -8.547 -82.519 1.00 62.01 C +ATOM 5631 CG LEU C 418 -5.122 -9.220 -82.313 1.00 57.70 C +ATOM 5632 CD1 LEU C 418 -4.432 -8.642 -81.096 1.00 64.76 C +ATOM 5633 CD2 LEU C 418 -5.208 -10.743 -82.229 1.00 53.59 C +ATOM 5634 N ASP C 419 -9.519 -7.827 -82.767 1.00 59.33 N +ATOM 5635 CA ASP C 419 -10.638 -6.910 -82.934 1.00 58.20 C +ATOM 5636 C ASP C 419 -11.558 -6.947 -81.720 1.00 63.39 C +ATOM 5637 O ASP C 419 -11.977 -5.900 -81.211 1.00 61.80 O +ATOM 5638 CB ASP C 419 -11.406 -7.259 -84.206 1.00 65.84 C +ATOM 5639 CG ASP C 419 -10.712 -6.756 -85.452 1.00 79.09 C +ATOM 5640 OD1 ASP C 419 -9.922 -5.789 -85.344 1.00 75.77 O +ATOM 5641 OD2 ASP C 419 -10.951 -7.334 -86.533 1.00 82.42 O +ATOM 5642 N ILE C 420 -11.898 -8.154 -81.257 1.00 61.55 N +ATOM 5643 CA ILE C 420 -12.728 -8.314 -80.063 1.00 57.32 C +ATOM 5644 C ILE C 420 -12.062 -7.687 -78.843 1.00 56.81 C +ATOM 5645 O ILE C 420 -12.729 -7.074 -78.000 1.00 53.30 O +ATOM 5646 CB ILE C 420 -13.034 -9.805 -79.852 1.00 50.35 C +ATOM 5647 CG1 ILE C 420 -13.673 -10.362 -81.124 1.00 50.13 C +ATOM 5648 CG2 ILE C 420 -13.953 -9.994 -78.664 1.00 49.71 C +ATOM 5649 CD1 ILE C 420 -13.706 -11.858 -81.188 1.00 58.01 C +ATOM 5650 N MET C 421 -10.742 -7.857 -78.716 1.00 59.04 N +ATOM 5651 CA MET C 421 -10.000 -7.253 -77.612 1.00 59.28 C +ATOM 5652 C MET C 421 -10.118 -5.732 -77.635 1.00 57.16 C +ATOM 5653 O MET C 421 -10.376 -5.099 -76.603 1.00 50.83 O +ATOM 5654 CB MET C 421 -8.535 -7.687 -77.689 1.00 59.45 C +ATOM 5655 CG MET C 421 -8.313 -9.167 -77.422 1.00 51.94 C +ATOM 5656 SD MET C 421 -8.985 -9.713 -75.843 1.00 49.24 S +ATOM 5657 CE MET C 421 -10.244 -10.864 -76.382 1.00 54.62 C +ATOM 5658 N ASP C 422 -9.925 -5.128 -78.810 1.00 57.91 N +ATOM 5659 CA ASP C 422 -10.121 -3.690 -78.945 1.00 57.43 C +ATOM 5660 C ASP C 422 -11.537 -3.288 -78.557 1.00 61.92 C +ATOM 5661 O ASP C 422 -11.752 -2.195 -78.019 1.00 57.24 O +ATOM 5662 CB ASP C 422 -9.823 -3.264 -80.383 1.00 58.65 C +ATOM 5663 CG ASP C 422 -8.360 -3.421 -80.745 1.00 63.05 C +ATOM 5664 OD1 ASP C 422 -7.580 -3.855 -79.872 1.00 62.68 O +ATOM 5665 OD2 ASP C 422 -7.992 -3.119 -81.900 1.00 69.03 O +ATOM 5666 N MET C 423 -12.500 -4.187 -78.745 1.00 59.04 N +ATOM 5667 CA MET C 423 -13.887 -3.893 -78.425 1.00 49.85 C +ATOM 5668 C MET C 423 -14.204 -4.135 -76.960 1.00 49.26 C +ATOM 5669 O MET C 423 -14.857 -3.303 -76.324 1.00 50.94 O +ATOM 5670 CB MET C 423 -14.816 -4.743 -79.293 1.00 44.71 C +ATOM 5671 CG MET C 423 -16.197 -4.922 -78.691 1.00 52.43 C +ATOM 5672 SD MET C 423 -17.213 -6.107 -79.579 1.00 38.00 S +ATOM 5673 CE MET C 423 -17.919 -5.046 -80.828 1.00 48.12 C +ATOM 5674 N THR C 424 -13.738 -5.248 -76.399 1.00 48.92 N +ATOM 5675 CA THR C 424 -14.067 -5.534 -75.009 1.00 57.10 C +ATOM 5676 C THR C 424 -13.390 -4.545 -74.065 1.00 57.08 C +ATOM 5677 O THR C 424 -13.930 -4.241 -72.993 1.00 53.13 O +ATOM 5678 CB THR C 424 -13.701 -6.980 -74.669 1.00 54.48 C +ATOM 5679 OG1 THR C 424 -14.096 -7.274 -73.323 1.00 57.46 O +ATOM 5680 CG2 THR C 424 -12.211 -7.216 -74.828 1.00 50.83 C +ATOM 5681 N ILE C 425 -12.239 -3.999 -74.457 1.00 53.01 N +ATOM 5682 CA ILE C 425 -11.663 -2.906 -73.685 1.00 50.20 C +ATOM 5683 C ILE C 425 -12.563 -1.684 -73.768 1.00 53.90 C +ATOM 5684 O ILE C 425 -12.854 -1.040 -72.752 1.00 53.62 O +ATOM 5685 CB ILE C 425 -10.241 -2.602 -74.183 1.00 42.56 C +ATOM 5686 CG1 ILE C 425 -9.331 -3.794 -73.913 1.00 40.76 C +ATOM 5687 CG2 ILE C 425 -9.691 -1.349 -73.526 1.00 42.44 C +ATOM 5688 CD1 ILE C 425 -7.926 -3.576 -74.361 1.00 51.19 C +ATOM 5689 N PHE C 426 -13.069 -1.390 -74.970 1.00 51.81 N +ATOM 5690 CA PHE C 426 -14.008 -0.289 -75.163 1.00 46.67 C +ATOM 5691 C PHE C 426 -15.239 -0.450 -74.273 1.00 50.15 C +ATOM 5692 O PHE C 426 -15.615 0.476 -73.546 1.00 49.84 O +ATOM 5693 CB PHE C 426 -14.389 -0.221 -76.647 1.00 45.59 C +ATOM 5694 CG PHE C 426 -15.212 0.982 -77.035 1.00 52.47 C +ATOM 5695 CD1 PHE C 426 -15.546 1.967 -76.121 1.00 57.01 C +ATOM 5696 CD2 PHE C 426 -15.698 1.094 -78.326 1.00 53.75 C +ATOM 5697 CE1 PHE C 426 -16.321 3.048 -76.495 1.00 59.29 C +ATOM 5698 CE2 PHE C 426 -16.476 2.173 -78.705 1.00 51.79 C +ATOM 5699 CZ PHE C 426 -16.788 3.150 -77.788 1.00 52.70 C +ATOM 5700 N ASP C 427 -15.882 -1.621 -74.320 1.00 53.81 N +ATOM 5701 CA ASP C 427 -17.120 -1.820 -73.566 1.00 56.58 C +ATOM 5702 C ASP C 427 -16.889 -1.722 -72.065 1.00 54.94 C +ATOM 5703 O ASP C 427 -17.791 -1.312 -71.323 1.00 48.02 O +ATOM 5704 CB ASP C 427 -17.736 -3.176 -73.909 1.00 59.47 C +ATOM 5705 CG ASP C 427 -18.331 -3.214 -75.300 1.00 58.47 C +ATOM 5706 OD1 ASP C 427 -18.810 -2.163 -75.775 1.00 58.40 O +ATOM 5707 OD2 ASP C 427 -18.303 -4.295 -75.925 1.00 56.13 O +ATOM 5708 N PHE C 428 -15.703 -2.122 -71.597 1.00 56.19 N +ATOM 5709 CA PHE C 428 -15.406 -2.031 -70.172 1.00 55.84 C +ATOM 5710 C PHE C 428 -15.212 -0.584 -69.738 1.00 56.42 C +ATOM 5711 O PHE C 428 -15.645 -0.197 -68.646 1.00 61.78 O +ATOM 5712 CB PHE C 428 -14.171 -2.859 -69.832 1.00 49.52 C +ATOM 5713 CG PHE C 428 -13.806 -2.814 -68.380 1.00 48.63 C +ATOM 5714 CD1 PHE C 428 -14.548 -3.515 -67.449 1.00 51.43 C +ATOM 5715 CD2 PHE C 428 -12.724 -2.075 -67.945 1.00 52.77 C +ATOM 5716 CE1 PHE C 428 -14.221 -3.475 -66.112 1.00 56.14 C +ATOM 5717 CE2 PHE C 428 -12.387 -2.034 -66.607 1.00 53.09 C +ATOM 5718 CZ PHE C 428 -13.138 -2.734 -65.689 1.00 55.45 C +ATOM 5719 N LEU C 429 -14.561 0.228 -70.573 1.00 48.02 N +ATOM 5720 CA LEU C 429 -14.407 1.638 -70.241 1.00 43.26 C +ATOM 5721 C LEU C 429 -15.757 2.318 -70.076 1.00 46.25 C +ATOM 5722 O LEU C 429 -15.888 3.249 -69.276 1.00 48.23 O +ATOM 5723 CB LEU C 429 -13.583 2.340 -71.316 1.00 43.69 C +ATOM 5724 CG LEU C 429 -12.165 1.800 -71.457 1.00 38.59 C +ATOM 5725 CD1 LEU C 429 -11.404 2.530 -72.547 1.00 38.00 C +ATOM 5726 CD2 LEU C 429 -11.458 1.931 -70.133 1.00 48.36 C +ATOM 5727 N MET C 430 -16.772 1.853 -70.803 1.00 45.68 N +ATOM 5728 CA MET C 430 -18.111 2.412 -70.694 1.00 48.78 C +ATOM 5729 C MET C 430 -18.987 1.693 -69.679 1.00 47.13 C +ATOM 5730 O MET C 430 -19.931 2.297 -69.155 1.00 46.98 O +ATOM 5731 CB MET C 430 -18.814 2.371 -72.054 1.00 52.30 C +ATOM 5732 CG MET C 430 -18.045 3.006 -73.192 1.00 48.92 C +ATOM 5733 SD MET C 430 -19.100 3.165 -74.642 1.00 49.86 S +ATOM 5734 CE MET C 430 -19.475 1.462 -75.010 1.00 55.90 C +ATOM 5735 N GLY C 431 -18.711 0.426 -69.394 1.00 46.16 N +ATOM 5736 CA GLY C 431 -19.640 -0.351 -68.605 1.00 51.24 C +ATOM 5737 C GLY C 431 -20.762 -0.942 -69.421 1.00 61.84 C +ATOM 5738 O GLY C 431 -21.807 -1.291 -68.863 1.00 59.86 O +ATOM 5739 N ASN C 432 -20.586 -1.035 -70.739 1.00 65.29 N +ATOM 5740 CA ASN C 432 -21.614 -1.548 -71.641 1.00 58.35 C +ATOM 5741 C ASN C 432 -21.519 -3.064 -71.671 1.00 61.96 C +ATOM 5742 O ASN C 432 -20.730 -3.634 -72.430 1.00 58.15 O +ATOM 5743 CB ASN C 432 -21.438 -0.983 -73.044 1.00 55.11 C +ATOM 5744 CG ASN C 432 -22.355 -1.650 -74.050 1.00 58.95 C +ATOM 5745 OD1 ASN C 432 -23.530 -1.877 -73.769 1.00 62.30 O +ATOM 5746 ND2 ASN C 432 -21.819 -1.990 -75.218 1.00 55.38 N +ATOM 5747 N MET C 433 -22.345 -3.728 -70.864 1.00 56.14 N +ATOM 5748 CA MET C 433 -22.370 -5.182 -70.824 1.00 57.62 C +ATOM 5749 C MET C 433 -23.461 -5.768 -71.710 1.00 52.22 C +ATOM 5750 O MET C 433 -23.888 -6.904 -71.487 1.00 58.50 O +ATOM 5751 CB MET C 433 -22.511 -5.672 -69.380 1.00 63.38 C +ATOM 5752 CG MET C 433 -23.400 -4.822 -68.492 1.00 62.56 C +ATOM 5753 SD MET C 433 -23.398 -5.415 -66.784 1.00 53.94 S +ATOM 5754 CE MET C 433 -24.134 -4.009 -65.944 1.00 65.35 C +ATOM 5755 N ASP C 434 -23.912 -5.022 -72.716 1.00 54.26 N +ATOM 5756 CA ASP C 434 -24.950 -5.472 -73.635 1.00 57.39 C +ATOM 5757 C ASP C 434 -24.383 -5.797 -75.018 1.00 58.24 C +ATOM 5758 O ASP C 434 -25.090 -5.709 -76.026 1.00 50.38 O +ATOM 5759 CB ASP C 434 -26.053 -4.418 -73.730 1.00 62.50 C +ATOM 5760 CG ASP C 434 -27.360 -4.978 -74.263 1.00 68.52 C +ATOM 5761 OD1 ASP C 434 -27.575 -6.200 -74.142 1.00 72.63 O +ATOM 5762 OD2 ASP C 434 -28.180 -4.195 -74.794 1.00 72.84 O +ATOM 5763 N ARG C 435 -23.105 -6.191 -75.074 1.00 63.96 N +ATOM 5764 CA ARG C 435 -22.428 -6.493 -76.338 1.00 57.38 C +ATOM 5765 C ARG C 435 -22.591 -7.975 -76.654 1.00 53.04 C +ATOM 5766 O ARG C 435 -21.718 -8.806 -76.401 1.00 52.27 O +ATOM 5767 CB ARG C 435 -20.953 -6.109 -76.271 1.00 53.33 C +ATOM 5768 CG ARG C 435 -20.215 -6.268 -77.597 1.00 44.84 C +ATOM 5769 CD ARG C 435 -20.636 -5.180 -78.570 1.00 49.88 C +ATOM 5770 NE ARG C 435 -20.220 -3.858 -78.112 1.00 53.46 N +ATOM 5771 CZ ARG C 435 -20.467 -2.730 -78.766 1.00 46.97 C +ATOM 5772 NH1 ARG C 435 -21.135 -2.761 -79.911 1.00 41.46 N +ATOM 5773 NH2 ARG C 435 -20.047 -1.574 -78.271 1.00 49.76 N +ATOM 5774 N HIS C 436 -23.726 -8.298 -77.268 1.00 55.13 N +ATOM 5775 CA HIS C 436 -24.036 -9.665 -77.653 1.00 56.92 C +ATOM 5776 C HIS C 436 -23.804 -9.945 -79.131 1.00 60.80 C +ATOM 5777 O HIS C 436 -23.861 -11.108 -79.538 1.00 60.69 O +ATOM 5778 CB HIS C 436 -25.497 -9.984 -77.305 1.00 58.70 C +ATOM 5779 CG HIS C 436 -26.490 -8.997 -77.848 1.00 66.33 C +ATOM 5780 ND1 HIS C 436 -26.138 -7.968 -78.694 1.00 67.95 N +ATOM 5781 CD2 HIS C 436 -27.828 -8.888 -77.665 1.00 73.36 C +ATOM 5782 CE1 HIS C 436 -27.213 -7.268 -79.009 1.00 73.44 C +ATOM 5783 NE2 HIS C 436 -28.252 -7.805 -78.396 1.00 79.56 N +ATOM 5784 N HIS C 437 -23.504 -8.922 -79.927 1.00 63.10 N +ATOM 5785 CA HIS C 437 -23.372 -9.053 -81.370 1.00 58.99 C +ATOM 5786 C HIS C 437 -22.404 -7.995 -81.869 1.00 54.69 C +ATOM 5787 O HIS C 437 -22.323 -6.896 -81.313 1.00 57.03 O +ATOM 5788 CB HIS C 437 -24.711 -8.873 -82.101 1.00 59.68 C +ATOM 5789 CG HIS C 437 -25.673 -10.003 -81.912 1.00 61.89 C +ATOM 5790 ND1 HIS C 437 -25.269 -11.289 -81.624 1.00 60.01 N +ATOM 5791 CD2 HIS C 437 -27.025 -10.037 -81.969 1.00 63.50 C +ATOM 5792 CE1 HIS C 437 -26.331 -12.067 -81.514 1.00 61.36 C +ATOM 5793 NE2 HIS C 437 -27.410 -11.332 -81.718 1.00 66.19 N +ATOM 5794 N TYR C 438 -21.662 -8.333 -82.918 1.00 43.84 N +ATOM 5795 CA TYR C 438 -20.783 -7.364 -83.560 1.00 43.75 C +ATOM 5796 C TYR C 438 -20.911 -7.530 -85.062 1.00 41.67 C +ATOM 5797 O TYR C 438 -20.701 -8.626 -85.586 1.00 48.94 O +ATOM 5798 CB TYR C 438 -19.332 -7.519 -83.100 1.00 44.46 C +ATOM 5799 CG TYR C 438 -18.729 -8.871 -83.353 1.00 43.50 C +ATOM 5800 CD1 TYR C 438 -18.962 -9.922 -82.486 1.00 48.78 C +ATOM 5801 CD2 TYR C 438 -17.880 -9.081 -84.425 1.00 44.38 C +ATOM 5802 CE1 TYR C 438 -18.400 -11.153 -82.702 1.00 52.92 C +ATOM 5803 CE2 TYR C 438 -17.309 -10.306 -84.651 1.00 47.43 C +ATOM 5804 CZ TYR C 438 -17.568 -11.340 -83.786 1.00 54.01 C +ATOM 5805 OH TYR C 438 -16.999 -12.570 -84.012 1.00 61.32 O +ATOM 5806 N GLU C 439 -21.318 -6.466 -85.740 1.00 38.00 N +ATOM 5807 CA GLU C 439 -21.527 -6.555 -87.170 1.00 38.00 C +ATOM 5808 C GLU C 439 -20.209 -6.346 -87.923 1.00 39.63 C +ATOM 5809 O GLU C 439 -19.195 -5.924 -87.359 1.00 38.31 O +ATOM 5810 CB GLU C 439 -22.592 -5.546 -87.607 1.00 39.91 C +ATOM 5811 CG GLU C 439 -24.017 -5.863 -87.112 1.00 38.00 C +ATOM 5812 CD GLU C 439 -25.063 -4.864 -87.627 1.00 44.19 C +ATOM 5813 OE1 GLU C 439 -25.104 -4.609 -88.852 1.00 41.41 O +ATOM 5814 OE2 GLU C 439 -25.855 -4.340 -86.812 1.00 49.75 O +ATOM 5815 N THR C 440 -20.231 -6.662 -89.220 1.00 45.99 N +ATOM 5816 CA THR C 440 -19.075 -6.465 -90.093 1.00 43.58 C +ATOM 5817 C THR C 440 -19.525 -5.890 -91.430 1.00 44.85 C +ATOM 5818 O THR C 440 -20.485 -5.117 -91.480 1.00 53.53 O +ATOM 5819 CB THR C 440 -18.315 -7.767 -90.324 1.00 46.85 C +ATOM 5820 OG1 THR C 440 -18.531 -8.649 -89.223 1.00 52.18 O +ATOM 5821 CG2 THR C 440 -16.831 -7.484 -90.437 1.00 49.08 C +ATOM 5822 N PHE C 441 -18.882 -6.282 -92.530 1.00 42.18 N +ATOM 5823 CA PHE C 441 -19.248 -5.684 -93.806 1.00 46.42 C +ATOM 5824 C PHE C 441 -19.279 -6.683 -94.957 1.00 54.46 C +ATOM 5825 O PHE C 441 -19.407 -6.258 -96.113 1.00 64.93 O +ATOM 5826 CB PHE C 441 -18.314 -4.506 -94.145 1.00 50.16 C +ATOM 5827 CG PHE C 441 -18.829 -3.153 -93.673 1.00 46.93 C +ATOM 5828 CD1 PHE C 441 -19.821 -2.479 -94.372 1.00 41.46 C +ATOM 5829 CD2 PHE C 441 -18.318 -2.561 -92.528 1.00 43.86 C +ATOM 5830 CE1 PHE C 441 -20.284 -1.247 -93.935 1.00 38.00 C +ATOM 5831 CE2 PHE C 441 -18.782 -1.331 -92.093 1.00 38.00 C +ATOM 5832 CZ PHE C 441 -19.763 -0.676 -92.796 1.00 38.00 C +ATOM 5833 N GLU C 442 -19.153 -7.984 -94.692 1.00 54.63 N +ATOM 5834 CA GLU C 442 -19.471 -9.011 -95.683 1.00 59.31 C +ATOM 5835 C GLU C 442 -18.625 -8.896 -96.947 1.00 59.95 C +ATOM 5836 O GLU C 442 -17.819 -9.785 -97.246 1.00 62.61 O +ATOM 5837 CB GLU C 442 -20.961 -8.942 -96.047 1.00 60.71 C +ATOM 5838 CG GLU C 442 -21.817 -10.118 -95.578 1.00 61.35 C +ATOM 5839 CD GLU C 442 -21.654 -11.365 -96.434 1.00 79.49 C +ATOM 5840 OE1 GLU C 442 -21.736 -12.483 -95.882 1.00 76.49 O +ATOM 5841 OE2 GLU C 442 -21.446 -11.226 -97.661 1.00 84.37 O +ATOM 5842 N LYS C 443 -18.790 -7.800 -97.692 1.00 56.42 N +ATOM 5843 CA LYS C 443 -18.082 -7.629 -98.955 1.00 62.35 C +ATOM 5844 C LYS C 443 -16.569 -7.601 -98.779 1.00 68.14 C +ATOM 5845 O LYS C 443 -15.843 -7.717 -99.771 1.00 80.59 O +ATOM 5846 CB LYS C 443 -18.558 -6.333 -99.636 1.00 73.74 C +ATOM 5847 CG LYS C 443 -18.213 -6.210-101.125 1.00101.07 C +ATOM 5848 CD LYS C 443 -18.810 -4.945-101.738 1.00103.04 C +ATOM 5849 CE LYS C 443 -18.482 -4.828-103.224 1.00107.22 C +ATOM 5850 NZ LYS C 443 -19.031 -3.577-103.826 1.00 99.10 N +ATOM 5851 N PHE C 444 -16.077 -7.533 -97.546 1.00 65.39 N +ATOM 5852 CA PHE C 444 -14.649 -7.476 -97.266 1.00 59.65 C +ATOM 5853 C PHE C 444 -14.058 -8.828 -96.932 1.00 57.70 C +ATOM 5854 O PHE C 444 -12.933 -9.124 -97.340 1.00 60.50 O +ATOM 5855 CB PHE C 444 -14.379 -6.530 -96.101 1.00 58.85 C +ATOM 5856 CG PHE C 444 -14.485 -5.083 -96.455 1.00 59.68 C +ATOM 5857 CD1 PHE C 444 -14.099 -4.636 -97.705 1.00 64.18 C +ATOM 5858 CD2 PHE C 444 -14.985 -4.171 -95.542 1.00 52.42 C +ATOM 5859 CE1 PHE C 444 -14.199 -3.306 -98.032 1.00 64.65 C +ATOM 5860 CE2 PHE C 444 -15.085 -2.845 -95.860 1.00 51.55 C +ATOM 5861 CZ PHE C 444 -14.694 -2.409 -97.108 1.00 67.12 C +ATOM 5862 N GLY C 445 -14.791 -9.641 -96.192 1.00 57.76 N +ATOM 5863 CA GLY C 445 -14.321 -10.909 -95.694 1.00 58.11 C +ATOM 5864 C GLY C 445 -14.062 -10.866 -94.203 1.00 54.82 C +ATOM 5865 O GLY C 445 -14.469 -9.943 -93.493 1.00 56.15 O +ATOM 5866 N ASN C 446 -13.324 -11.867 -93.732 1.00 59.59 N +ATOM 5867 CA ASN C 446 -13.062 -12.018 -92.309 1.00 61.76 C +ATOM 5868 C ASN C 446 -11.867 -11.189 -91.852 1.00 67.68 C +ATOM 5869 O ASN C 446 -11.317 -11.447 -90.775 1.00 71.35 O +ATOM 5870 CB ASN C 446 -12.839 -13.499 -91.963 1.00 61.55 C +ATOM 5871 CG ASN C 446 -14.122 -14.330 -92.016 1.00 54.37 C +ATOM 5872 OD1 ASN C 446 -15.185 -13.869 -91.613 1.00 52.93 O +ATOM 5873 ND2 ASN C 446 -14.012 -15.575 -92.481 1.00 48.37 N +ATOM 5874 N ASP C 447 -11.492 -10.167 -92.619 1.00 68.87 N +ATOM 5875 CA ASP C 447 -10.274 -9.399 -92.395 1.00 69.52 C +ATOM 5876 C ASP C 447 -10.574 -7.916 -92.217 1.00 69.72 C +ATOM 5877 O ASP C 447 -9.895 -7.060 -92.789 1.00 72.95 O +ATOM 5878 CB ASP C 447 -9.296 -9.582 -93.554 1.00 69.27 C +ATOM 5879 CG ASP C 447 -8.970 -11.034 -93.825 1.00 74.61 C +ATOM 5880 OD1 ASP C 447 -8.843 -11.820 -92.860 1.00 74.38 O +ATOM 5881 OD2 ASP C 447 -8.876 -11.392 -95.016 1.00 74.00 O +ATOM 5882 N THR C 448 -11.598 -7.586 -91.431 1.00 66.96 N +ATOM 5883 CA THR C 448 -11.964 -6.195 -91.205 1.00 58.39 C +ATOM 5884 C THR C 448 -12.283 -5.970 -89.740 1.00 59.69 C +ATOM 5885 O THR C 448 -12.267 -6.892 -88.919 1.00 65.27 O +ATOM 5886 CB THR C 448 -13.161 -5.755 -92.044 1.00 51.07 C +ATOM 5887 OG1 THR C 448 -14.119 -6.816 -92.121 1.00 57.58 O +ATOM 5888 CG2 THR C 448 -12.699 -5.381 -93.409 1.00 60.72 C +ATOM 5889 N PHE C 449 -12.576 -4.714 -89.431 1.00 54.84 N +ATOM 5890 CA PHE C 449 -12.913 -4.282 -88.091 1.00 53.72 C +ATOM 5891 C PHE C 449 -14.347 -4.661 -87.755 1.00 52.07 C +ATOM 5892 O PHE C 449 -15.091 -5.213 -88.572 1.00 49.75 O +ATOM 5893 CB PHE C 449 -12.735 -2.777 -87.961 1.00 59.14 C +ATOM 5894 CG PHE C 449 -13.769 -1.983 -88.711 1.00 53.62 C +ATOM 5895 CD1 PHE C 449 -13.701 -1.865 -90.087 1.00 48.40 C +ATOM 5896 CD2 PHE C 449 -14.808 -1.359 -88.040 1.00 56.39 C +ATOM 5897 CE1 PHE C 449 -14.639 -1.136 -90.779 1.00 46.01 C +ATOM 5898 CE2 PHE C 449 -15.752 -0.630 -88.730 1.00 50.13 C +ATOM 5899 CZ PHE C 449 -15.666 -0.519 -90.102 1.00 43.64 C +ATOM 5900 N ILE C 450 -14.745 -4.323 -86.537 1.00 48.57 N +ATOM 5901 CA ILE C 450 -16.088 -4.577 -86.048 1.00 46.73 C +ATOM 5902 C ILE C 450 -16.744 -3.232 -85.764 1.00 40.15 C +ATOM 5903 O ILE C 450 -16.137 -2.359 -85.135 1.00 38.00 O +ATOM 5904 CB ILE C 450 -16.066 -5.489 -84.808 1.00 43.94 C +ATOM 5905 CG1 ILE C 450 -15.129 -4.947 -83.737 1.00 53.37 C +ATOM 5906 CG2 ILE C 450 -15.547 -6.856 -85.183 1.00 42.73 C +ATOM 5907 CD1 ILE C 450 -14.913 -5.928 -82.612 1.00 58.00 C +ATOM 5908 N ILE C 451 -17.937 -3.032 -86.314 1.00 38.30 N +ATOM 5909 CA ILE C 451 -18.683 -1.796 -86.100 1.00 38.00 C +ATOM 5910 C ILE C 451 -19.290 -1.834 -84.705 1.00 38.00 C +ATOM 5911 O ILE C 451 -20.108 -2.706 -84.392 1.00 38.00 O +ATOM 5912 CB ILE C 451 -19.773 -1.597 -87.165 1.00 38.00 C +ATOM 5913 CG1 ILE C 451 -19.208 -1.712 -88.576 1.00 38.00 C +ATOM 5914 CG2 ILE C 451 -20.445 -0.254 -87.004 1.00 44.95 C +ATOM 5915 CD1 ILE C 451 -19.407 -3.052 -89.179 1.00 38.00 C +ATOM 5916 N HIS C 452 -18.914 -0.870 -83.877 1.00 38.00 N +ATOM 5917 CA HIS C 452 -19.402 -0.776 -82.508 1.00 38.04 C +ATOM 5918 C HIS C 452 -20.717 0.006 -82.537 1.00 39.16 C +ATOM 5919 O HIS C 452 -20.719 1.239 -82.530 1.00 38.95 O +ATOM 5920 CB HIS C 452 -18.351 -0.116 -81.622 1.00 40.91 C +ATOM 5921 CG HIS C 452 -17.014 -0.808 -81.619 1.00 39.65 C +ATOM 5922 ND1 HIS C 452 -15.851 -0.173 -81.234 1.00 43.03 N +ATOM 5923 CD2 HIS C 452 -16.657 -2.076 -81.931 1.00 39.52 C +ATOM 5924 CE1 HIS C 452 -14.837 -1.016 -81.317 1.00 40.34 C +ATOM 5925 NE2 HIS C 452 -15.300 -2.179 -81.736 1.00 38.00 N +ATOM 5926 N LEU C 453 -21.835 -0.711 -82.588 1.00 41.81 N +ATOM 5927 CA LEU C 453 -23.176 -0.139 -82.661 1.00 38.91 C +ATOM 5928 C LEU C 453 -23.931 -0.397 -81.364 1.00 44.04 C +ATOM 5929 O LEU C 453 -23.561 -1.262 -80.569 1.00 52.08 O +ATOM 5930 CB LEU C 453 -23.963 -0.745 -83.821 1.00 42.79 C +ATOM 5931 CG LEU C 453 -23.453 -0.449 -85.218 1.00 38.00 C +ATOM 5932 CD1 LEU C 453 -24.242 -1.251 -86.224 1.00 38.00 C +ATOM 5933 CD2 LEU C 453 -23.579 1.024 -85.483 1.00 46.03 C +ATOM 5934 N ASP C 454 -25.029 0.338 -81.184 1.00 46.82 N +ATOM 5935 CA ASP C 454 -25.901 0.224 -80.008 1.00 63.10 C +ATOM 5936 C ASP C 454 -25.110 0.350 -78.701 1.00 59.49 C +ATOM 5937 O ASP C 454 -25.120 -0.535 -77.841 1.00 62.37 O +ATOM 5938 CB ASP C 454 -26.691 -1.091 -80.042 1.00 74.63 C +ATOM 5939 CG ASP C 454 -27.769 -1.102 -81.114 1.00 71.48 C +ATOM 5940 OD1 ASP C 454 -27.404 -1.222 -82.300 1.00 67.62 O +ATOM 5941 OD2 ASP C 454 -28.975 -1.026 -80.772 1.00 73.32 O +ATOM 5942 N ASN C 455 -24.460 1.498 -78.539 1.00 46.95 N +ATOM 5943 CA ASN C 455 -23.635 1.753 -77.368 1.00 44.80 C +ATOM 5944 C ASN C 455 -24.414 2.400 -76.249 1.00 50.74 C +ATOM 5945 O ASN C 455 -23.814 2.822 -75.256 1.00 51.23 O +ATOM 5946 CB ASN C 455 -22.462 2.654 -77.729 1.00 42.33 C +ATOM 5947 CG ASN C 455 -21.772 2.210 -78.965 1.00 44.24 C +ATOM 5948 OD1 ASN C 455 -21.510 1.025 -79.134 1.00 48.20 O +ATOM 5949 ND2 ASN C 455 -21.482 3.148 -79.858 1.00 44.74 N +ATOM 5950 N GLY C 456 -25.736 2.461 -76.372 1.00 52.71 N +ATOM 5951 CA GLY C 456 -26.522 3.233 -75.439 1.00 54.56 C +ATOM 5952 C GLY C 456 -26.585 2.658 -74.047 1.00 52.40 C +ATOM 5953 O GLY C 456 -27.086 3.336 -73.145 1.00 57.80 O +ATOM 5954 N ARG C 457 -26.080 1.446 -73.842 1.00 49.53 N +ATOM 5955 CA ARG C 457 -26.161 0.794 -72.545 1.00 52.19 C +ATOM 5956 C ARG C 457 -24.952 1.072 -71.665 1.00 54.48 C +ATOM 5957 O ARG C 457 -24.898 0.579 -70.534 1.00 59.43 O +ATOM 5958 CB ARG C 457 -26.341 -0.711 -72.734 1.00 58.06 C +ATOM 5959 CG ARG C 457 -27.488 -1.055 -73.663 1.00 57.14 C +ATOM 5960 CD ARG C 457 -28.652 -1.682 -72.918 1.00 54.75 C +ATOM 5961 NE ARG C 457 -29.777 -1.934 -73.813 1.00 50.53 N +ATOM 5962 CZ ARG C 457 -30.875 -2.594 -73.465 1.00 52.37 C +ATOM 5963 NH1 ARG C 457 -31.002 -3.082 -72.241 1.00 53.04 N +ATOM 5964 NH2 ARG C 457 -31.848 -2.768 -74.343 1.00 58.54 N +ATOM 5965 N GLY C 458 -23.980 1.835 -72.153 1.00 49.48 N +ATOM 5966 CA GLY C 458 -22.854 2.213 -71.336 1.00 49.02 C +ATOM 5967 C GLY C 458 -23.168 3.429 -70.487 1.00 56.34 C +ATOM 5968 O GLY C 458 -24.236 4.036 -70.579 1.00 50.47 O +ATOM 5969 N PHE C 459 -22.207 3.773 -69.631 1.00 61.75 N +ATOM 5970 CA PHE C 459 -22.279 4.959 -68.776 1.00 57.96 C +ATOM 5971 C PHE C 459 -23.558 4.968 -67.939 1.00 60.78 C +ATOM 5972 O PHE C 459 -24.269 5.971 -67.846 1.00 59.78 O +ATOM 5973 CB PHE C 459 -22.158 6.238 -69.605 1.00 52.14 C +ATOM 5974 CG PHE C 459 -20.879 6.334 -70.377 1.00 47.28 C +ATOM 5975 CD1 PHE C 459 -19.739 6.848 -69.792 1.00 49.05 C +ATOM 5976 CD2 PHE C 459 -20.820 5.911 -71.692 1.00 47.86 C +ATOM 5977 CE1 PHE C 459 -18.555 6.935 -70.503 1.00 50.16 C +ATOM 5978 CE2 PHE C 459 -19.646 5.996 -72.410 1.00 52.78 C +ATOM 5979 CZ PHE C 459 -18.509 6.509 -71.816 1.00 51.94 C +ATOM 5980 N GLY C 460 -23.861 3.824 -67.335 1.00 62.11 N +ATOM 5981 CA GLY C 460 -25.029 3.733 -66.486 1.00 59.76 C +ATOM 5982 C GLY C 460 -24.680 3.750 -65.016 1.00 61.98 C +ATOM 5983 O GLY C 460 -25.520 4.054 -64.165 1.00 63.15 O +ATOM 5984 N LYS C 461 -23.426 3.438 -64.705 1.00 56.81 N +ATOM 5985 CA LYS C 461 -22.964 3.361 -63.327 1.00 58.61 C +ATOM 5986 C LYS C 461 -21.563 3.947 -63.275 1.00 59.80 C +ATOM 5987 O LYS C 461 -20.678 3.502 -64.012 1.00 54.16 O +ATOM 5988 CB LYS C 461 -22.982 1.912 -62.817 1.00 66.55 C +ATOM 5989 CG LYS C 461 -24.366 1.249 -62.878 1.00 65.18 C +ATOM 5990 CD LYS C 461 -24.325 -0.233 -62.526 1.00 62.33 C +ATOM 5991 CE LYS C 461 -24.084 -0.447 -61.041 1.00 81.95 C +ATOM 5992 NZ LYS C 461 -25.144 0.195 -60.211 1.00 80.31 N +ATOM 5993 N HIS C 462 -21.376 4.969 -62.440 1.00 64.70 N +ATOM 5994 CA HIS C 462 -20.079 5.617 -62.287 1.00 67.33 C +ATOM 5995 C HIS C 462 -19.347 5.190 -61.024 1.00 73.43 C +ATOM 5996 O HIS C 462 -18.116 5.293 -60.977 1.00 70.39 O +ATOM 5997 CB HIS C 462 -20.244 7.142 -62.283 1.00 59.76 C +ATOM 5998 CG HIS C 462 -21.065 7.649 -61.141 1.00 61.73 C +ATOM 5999 ND1 HIS C 462 -20.549 7.838 -59.878 1.00 66.83 N +ATOM 6000 CD2 HIS C 462 -22.374 7.987 -61.068 1.00 64.80 C +ATOM 6001 CE1 HIS C 462 -21.503 8.281 -59.078 1.00 70.46 C +ATOM 6002 NE2 HIS C 462 -22.622 8.376 -59.775 1.00 63.41 N +ATOM 6003 N SER C 463 -20.069 4.714 -60.013 1.00 73.02 N +ATOM 6004 CA SER C 463 -19.482 4.187 -58.791 1.00 74.26 C +ATOM 6005 C SER C 463 -19.245 2.683 -58.856 1.00 81.11 C +ATOM 6006 O SER C 463 -19.003 2.057 -57.818 1.00 93.29 O +ATOM 6007 CB SER C 463 -20.382 4.523 -57.598 1.00 77.03 C +ATOM 6008 OG SER C 463 -21.654 3.905 -57.730 1.00 76.03 O +ATOM 6009 N HIS C 464 -19.300 2.092 -60.046 1.00 76.33 N +ATOM 6010 CA HIS C 464 -19.204 0.649 -60.200 1.00 76.78 C +ATOM 6011 C HIS C 464 -18.414 0.326 -61.457 1.00 69.77 C +ATOM 6012 O HIS C 464 -18.562 0.995 -62.483 1.00 69.79 O +ATOM 6013 CB HIS C 464 -20.597 0.007 -60.267 1.00 70.53 C +ATOM 6014 CG HIS C 464 -20.584 -1.488 -60.177 1.00 74.02 C +ATOM 6015 ND1 HIS C 464 -19.912 -2.285 -61.079 1.00 73.08 N +ATOM 6016 CD2 HIS C 464 -21.166 -2.332 -59.293 1.00 79.13 C +ATOM 6017 CE1 HIS C 464 -20.077 -3.554 -60.754 1.00 73.04 C +ATOM 6018 NE2 HIS C 464 -20.835 -3.610 -59.674 1.00 82.92 N +ATOM 6019 N ASP C 465 -17.566 -0.691 -61.365 1.00 64.36 N +ATOM 6020 CA ASP C 465 -16.805 -1.187 -62.507 1.00 64.59 C +ATOM 6021 C ASP C 465 -17.205 -2.641 -62.727 1.00 65.49 C +ATOM 6022 O ASP C 465 -16.792 -3.530 -61.976 1.00 64.43 O +ATOM 6023 CB ASP C 465 -15.307 -1.043 -62.278 1.00 66.08 C +ATOM 6024 CG ASP C 465 -14.909 0.374 -61.955 1.00 67.26 C +ATOM 6025 OD1 ASP C 465 -15.608 1.297 -62.419 1.00 71.65 O +ATOM 6026 OD2 ASP C 465 -13.906 0.565 -61.235 1.00 66.83 O +ATOM 6027 N GLU C 466 -18.025 -2.875 -63.743 1.00 68.10 N +ATOM 6028 CA GLU C 466 -18.492 -4.220 -64.055 1.00 64.88 C +ATOM 6029 C GLU C 466 -17.337 -5.005 -64.656 1.00 59.26 C +ATOM 6030 O GLU C 466 -16.997 -4.838 -65.829 1.00 57.42 O +ATOM 6031 CB GLU C 466 -19.683 -4.165 -65.003 1.00 69.82 C +ATOM 6032 CG GLU C 466 -20.218 -5.527 -65.371 1.00 67.20 C +ATOM 6033 CD GLU C 466 -20.812 -6.250 -64.183 1.00 69.86 C +ATOM 6034 OE1 GLU C 466 -21.098 -5.590 -63.161 1.00 67.08 O +ATOM 6035 OE2 GLU C 466 -20.994 -7.481 -64.272 1.00 78.82 O +ATOM 6036 N MET C 467 -16.721 -5.862 -63.843 1.00 58.88 N +ATOM 6037 CA MET C 467 -15.556 -6.622 -64.274 1.00 63.32 C +ATOM 6038 C MET C 467 -15.898 -7.733 -65.260 1.00 61.09 C +ATOM 6039 O MET C 467 -14.995 -8.236 -65.941 1.00 52.84 O +ATOM 6040 CB MET C 467 -14.856 -7.204 -63.047 1.00 62.08 C +ATOM 6041 CG MET C 467 -14.407 -6.146 -62.065 1.00 50.85 C +ATOM 6042 SD MET C 467 -13.290 -4.967 -62.843 1.00 61.91 S +ATOM 6043 CE MET C 467 -11.947 -6.045 -63.352 1.00 63.81 C +ATOM 6044 N SER C 468 -17.176 -8.099 -65.376 1.00 58.27 N +ATOM 6045 CA SER C 468 -17.562 -9.184 -66.269 1.00 55.53 C +ATOM 6046 C SER C 468 -17.234 -8.861 -67.718 1.00 53.34 C +ATOM 6047 O SER C 468 -16.980 -9.770 -68.516 1.00 56.87 O +ATOM 6048 CB SER C 468 -19.056 -9.473 -66.116 1.00 55.76 C +ATOM 6049 OG SER C 468 -19.374 -9.789 -64.772 1.00 60.87 O +ATOM 6050 N ILE C 469 -17.207 -7.578 -68.072 1.00 49.60 N +ATOM 6051 CA ILE C 469 -16.889 -7.213 -69.443 1.00 49.15 C +ATOM 6052 C ILE C 469 -15.447 -7.565 -69.763 1.00 50.27 C +ATOM 6053 O ILE C 469 -15.125 -7.930 -70.899 1.00 53.15 O +ATOM 6054 CB ILE C 469 -17.158 -5.716 -69.664 1.00 50.19 C +ATOM 6055 CG1 ILE C 469 -18.588 -5.371 -69.259 1.00 50.71 C +ATOM 6056 CG2 ILE C 469 -16.897 -5.334 -71.109 1.00 52.61 C +ATOM 6057 CD1 ILE C 469 -18.880 -3.897 -69.315 1.00 53.54 C +ATOM 6058 N LEU C 470 -14.560 -7.478 -68.774 1.00 48.73 N +ATOM 6059 CA LEU C 470 -13.148 -7.737 -69.013 1.00 51.15 C +ATOM 6060 C LEU C 470 -12.839 -9.215 -69.215 1.00 53.27 C +ATOM 6061 O LEU C 470 -11.750 -9.536 -69.700 1.00 53.00 O +ATOM 6062 CB LEU C 470 -12.319 -7.181 -67.853 1.00 51.97 C +ATOM 6063 CG LEU C 470 -11.149 -6.266 -68.229 1.00 53.44 C +ATOM 6064 CD1 LEU C 470 -9.944 -7.058 -68.701 1.00 47.40 C +ATOM 6065 CD2 LEU C 470 -11.574 -5.278 -69.294 1.00 52.35 C +ATOM 6066 N VAL C 471 -13.780 -10.108 -68.883 1.00 52.09 N +ATOM 6067 CA VAL C 471 -13.475 -11.544 -68.905 1.00 46.19 C +ATOM 6068 C VAL C 471 -12.948 -12.007 -70.251 1.00 45.20 C +ATOM 6069 O VAL C 471 -12.012 -12.820 -70.274 1.00 43.72 O +ATOM 6070 CB VAL C 471 -14.703 -12.342 -68.429 1.00 47.21 C +ATOM 6071 CG1 VAL C 471 -14.426 -13.826 -68.473 1.00 51.09 C +ATOM 6072 CG2 VAL C 471 -15.092 -11.911 -67.026 1.00 46.16 C +ATOM 6073 N PRO C 472 -13.462 -11.543 -71.400 1.00 46.97 N +ATOM 6074 CA PRO C 472 -12.795 -11.845 -72.681 1.00 46.70 C +ATOM 6075 C PRO C 472 -11.297 -11.587 -72.687 1.00 48.52 C +ATOM 6076 O PRO C 472 -10.553 -12.313 -73.359 1.00 47.06 O +ATOM 6077 CB PRO C 472 -13.518 -10.923 -73.671 1.00 48.92 C +ATOM 6078 CG PRO C 472 -14.841 -10.596 -73.027 1.00 53.54 C +ATOM 6079 CD PRO C 472 -14.846 -11.083 -71.610 1.00 46.90 C +ATOM 6080 N LEU C 473 -10.838 -10.547 -71.988 1.00 50.99 N +ATOM 6081 CA LEU C 473 -9.415 -10.223 -71.978 1.00 48.76 C +ATOM 6082 C LEU C 473 -8.647 -11.068 -70.968 1.00 55.72 C +ATOM 6083 O LEU C 473 -7.532 -11.520 -71.256 1.00 57.88 O +ATOM 6084 CB LEU C 473 -9.224 -8.740 -71.672 1.00 40.66 C +ATOM 6085 CG LEU C 473 -7.785 -8.236 -71.684 1.00 38.00 C +ATOM 6086 CD1 LEU C 473 -7.125 -8.610 -72.993 1.00 43.05 C +ATOM 6087 CD2 LEU C 473 -7.747 -6.736 -71.472 1.00 45.86 C +ATOM 6088 N THR C 474 -9.229 -11.307 -69.789 1.00 54.47 N +ATOM 6089 CA THR C 474 -8.549 -12.104 -68.775 1.00 52.34 C +ATOM 6090 C THR C 474 -8.447 -13.574 -69.155 1.00 54.69 C +ATOM 6091 O THR C 474 -7.572 -14.271 -68.634 1.00 60.73 O +ATOM 6092 CB THR C 474 -9.260 -11.969 -67.429 1.00 47.79 C +ATOM 6093 OG1 THR C 474 -10.600 -12.460 -67.548 1.00 51.05 O +ATOM 6094 CG2 THR C 474 -9.285 -10.522 -66.977 1.00 49.45 C +ATOM 6095 N GLN C 475 -9.299 -14.056 -70.059 1.00 52.61 N +ATOM 6096 CA GLN C 475 -9.227 -15.445 -70.493 1.00 53.56 C +ATOM 6097 C GLN C 475 -8.405 -15.615 -71.756 1.00 57.38 C +ATOM 6098 O GLN C 475 -7.828 -16.688 -71.968 1.00 62.63 O +ATOM 6099 CB GLN C 475 -10.634 -16.011 -70.718 1.00 51.29 C +ATOM 6100 CG GLN C 475 -11.457 -16.116 -69.445 1.00 53.66 C +ATOM 6101 CD GLN C 475 -12.870 -16.628 -69.678 1.00 54.25 C +ATOM 6102 OE1 GLN C 475 -13.380 -16.616 -70.800 1.00 51.34 O +ATOM 6103 NE2 GLN C 475 -13.518 -17.066 -68.605 1.00 58.42 N +ATOM 6104 N CYS C 476 -8.350 -14.588 -72.602 1.00 54.77 N +ATOM 6105 CA CYS C 476 -7.587 -14.646 -73.842 1.00 58.31 C +ATOM 6106 C CYS C 476 -6.169 -14.129 -73.686 1.00 61.05 C +ATOM 6107 O CYS C 476 -5.233 -14.709 -74.247 1.00 60.29 O +ATOM 6108 CB CYS C 476 -8.299 -13.849 -74.930 1.00 56.49 C +ATOM 6109 SG CYS C 476 -9.631 -14.773 -75.672 1.00 81.38 S +ATOM 6110 N CYS C 477 -6.016 -13.019 -72.974 1.00 58.55 N +ATOM 6111 CA CYS C 477 -4.717 -12.458 -72.628 1.00 66.27 C +ATOM 6112 C CYS C 477 -3.837 -12.260 -73.862 1.00 62.82 C +ATOM 6113 O CYS C 477 -2.783 -12.877 -74.029 1.00 59.88 O +ATOM 6114 CB CYS C 477 -4.033 -13.313 -71.571 1.00 69.08 C +ATOM 6115 SG CYS C 477 -4.540 -12.813 -69.927 1.00 83.35 S +ATOM 6116 N ARG C 478 -4.312 -11.377 -74.733 1.00 60.84 N +ATOM 6117 CA ARG C 478 -3.547 -10.904 -75.873 1.00 62.17 C +ATOM 6118 C ARG C 478 -4.228 -9.656 -76.408 1.00 60.59 C +ATOM 6119 O ARG C 478 -5.457 -9.557 -76.383 1.00 53.22 O +ATOM 6120 CB ARG C 478 -3.418 -11.965 -76.968 1.00 57.92 C +ATOM 6121 CG ARG C 478 -4.730 -12.496 -77.469 1.00 62.07 C +ATOM 6122 CD ARG C 478 -4.545 -13.376 -78.693 1.00 67.00 C +ATOM 6123 NE ARG C 478 -3.245 -14.037 -78.741 1.00 69.50 N +ATOM 6124 CZ ARG C 478 -2.260 -13.684 -79.559 1.00 66.81 C +ATOM 6125 NH1 ARG C 478 -2.429 -12.670 -80.393 1.00 62.39 N +ATOM 6126 NH2 ARG C 478 -1.110 -14.344 -79.546 1.00 68.61 N +ATOM 6127 N VAL C 479 -3.421 -8.694 -76.859 1.00 64.49 N +ATOM 6128 CA VAL C 479 -3.913 -7.398 -77.309 1.00 59.86 C +ATOM 6129 C VAL C 479 -3.062 -6.914 -78.474 1.00 65.87 C +ATOM 6130 O VAL C 479 -1.957 -7.403 -78.724 1.00 67.05 O +ATOM 6131 CB VAL C 479 -3.903 -6.335 -76.189 1.00 57.94 C +ATOM 6132 CG1 VAL C 479 -5.075 -6.543 -75.254 1.00 61.87 C +ATOM 6133 CG2 VAL C 479 -2.578 -6.363 -75.437 1.00 62.67 C +ATOM 6134 N LYS C 480 -3.593 -5.917 -79.170 1.00 68.19 N +ATOM 6135 CA LYS C 480 -2.899 -5.304 -80.288 1.00 66.97 C +ATOM 6136 C LYS C 480 -1.883 -4.310 -79.746 1.00 69.25 C +ATOM 6137 O LYS C 480 -2.232 -3.416 -78.967 1.00 66.86 O +ATOM 6138 CB LYS C 480 -3.910 -4.613 -81.205 1.00 64.60 C +ATOM 6139 CG LYS C 480 -3.352 -4.116 -82.522 1.00 72.24 C +ATOM 6140 CD LYS C 480 -4.436 -3.425 -83.336 1.00 67.37 C +ATOM 6141 CE LYS C 480 -5.605 -4.361 -83.599 1.00 59.15 C +ATOM 6142 NZ LYS C 480 -6.726 -3.664 -84.289 1.00 58.86 N +ATOM 6143 N ARG C 481 -0.623 -4.466 -80.161 1.00 69.67 N +ATOM 6144 CA ARG C 481 0.427 -3.599 -79.634 1.00 69.38 C +ATOM 6145 C ARG C 481 0.092 -2.132 -79.872 1.00 69.32 C +ATOM 6146 O ARG C 481 0.352 -1.278 -79.013 1.00 64.33 O +ATOM 6147 CB ARG C 481 1.776 -3.953 -80.260 1.00 65.79 C +ATOM 6148 CG ARG C 481 2.897 -3.061 -79.761 1.00 73.50 C +ATOM 6149 CD ARG C 481 4.253 -3.422 -80.334 1.00 84.09 C +ATOM 6150 NE ARG C 481 5.278 -2.493 -79.860 1.00 83.91 N +ATOM 6151 CZ ARG C 481 6.573 -2.592 -80.144 1.00 88.06 C +ATOM 6152 NH1 ARG C 481 7.426 -1.695 -79.667 1.00 86.20 N +ATOM 6153 NH2 ARG C 481 7.015 -3.589 -80.901 1.00 83.15 N +ATOM 6154 N SER C 482 -0.532 -1.832 -81.016 1.00 64.47 N +ATOM 6155 CA SER C 482 -0.972 -0.471 -81.302 1.00 61.86 C +ATOM 6156 C SER C 482 -1.859 0.073 -80.189 1.00 60.94 C +ATOM 6157 O SER C 482 -1.706 1.226 -79.769 1.00 57.44 O +ATOM 6158 CB SER C 482 -1.710 -0.445 -82.639 1.00 56.46 C +ATOM 6159 OG SER C 482 -2.250 0.837 -82.901 1.00 65.03 O +ATOM 6160 N THR C 483 -2.779 -0.747 -79.687 1.00 61.44 N +ATOM 6161 CA THR C 483 -3.694 -0.286 -78.651 1.00 63.59 C +ATOM 6162 C THR C 483 -3.044 -0.287 -77.272 1.00 67.94 C +ATOM 6163 O THR C 483 -3.394 0.547 -76.429 1.00 64.11 O +ATOM 6164 CB THR C 483 -4.958 -1.145 -78.648 1.00 62.76 C +ATOM 6165 OG1 THR C 483 -4.661 -2.434 -78.101 1.00 65.27 O +ATOM 6166 CG2 THR C 483 -5.478 -1.313 -80.068 1.00 57.63 C +ATOM 6167 N TYR C 484 -2.118 -1.216 -77.018 1.00 71.08 N +ATOM 6168 CA TYR C 484 -1.455 -1.270 -75.718 1.00 65.58 C +ATOM 6169 C TYR C 484 -0.666 0.005 -75.458 1.00 64.06 C +ATOM 6170 O TYR C 484 -0.791 0.624 -74.394 1.00 59.06 O +ATOM 6171 CB TYR C 484 -0.535 -2.489 -75.648 1.00 61.11 C +ATOM 6172 CG TYR C 484 -0.132 -2.881 -74.243 1.00 65.93 C +ATOM 6173 CD1 TYR C 484 -0.669 -2.238 -73.135 1.00 71.97 C +ATOM 6174 CD2 TYR C 484 0.800 -3.886 -74.024 1.00 66.65 C +ATOM 6175 CE1 TYR C 484 -0.299 -2.594 -71.847 1.00 75.70 C +ATOM 6176 CE2 TYR C 484 1.178 -4.250 -72.743 1.00 74.06 C +ATOM 6177 CZ TYR C 484 0.624 -3.602 -71.658 1.00 75.93 C +ATOM 6178 OH TYR C 484 0.994 -3.960 -70.381 1.00 75.82 O +ATOM 6179 N LEU C 485 0.159 0.408 -76.425 1.00 60.65 N +ATOM 6180 CA LEU C 485 0.932 1.634 -76.275 1.00 60.08 C +ATOM 6181 C LEU C 485 0.027 2.854 -76.131 1.00 60.97 C +ATOM 6182 O LEU C 485 0.347 3.775 -75.372 1.00 62.08 O +ATOM 6183 CB LEU C 485 1.883 1.780 -77.465 1.00 58.68 C +ATOM 6184 CG LEU C 485 2.889 0.634 -77.637 1.00 61.49 C +ATOM 6185 CD1 LEU C 485 3.784 0.849 -78.849 1.00 57.24 C +ATOM 6186 CD2 LEU C 485 3.735 0.465 -76.378 1.00 66.21 C +ATOM 6187 N ARG C 486 -1.125 2.860 -76.812 1.00 60.45 N +ATOM 6188 CA ARG C 486 -2.086 3.948 -76.641 1.00 60.21 C +ATOM 6189 C ARG C 486 -2.638 3.978 -75.222 1.00 60.05 C +ATOM 6190 O ARG C 486 -2.617 5.020 -74.557 1.00 59.59 O +ATOM 6191 CB ARG C 486 -3.238 3.807 -77.636 1.00 61.86 C +ATOM 6192 CG ARG C 486 -2.929 4.175 -79.069 1.00 59.60 C +ATOM 6193 CD ARG C 486 -4.228 4.360 -79.831 1.00 60.47 C +ATOM 6194 NE ARG C 486 -4.422 3.330 -80.843 1.00 61.21 N +ATOM 6195 CZ ARG C 486 -4.016 3.438 -82.102 1.00 64.76 C +ATOM 6196 NH1 ARG C 486 -3.388 4.532 -82.511 1.00 66.17 N +ATOM 6197 NH2 ARG C 486 -4.236 2.450 -82.955 1.00 68.03 N +ATOM 6198 N LEU C 487 -3.159 2.839 -74.754 1.00 61.75 N +ATOM 6199 CA LEU C 487 -3.782 2.768 -73.434 1.00 68.26 C +ATOM 6200 C LEU C 487 -2.825 3.204 -72.330 1.00 72.99 C +ATOM 6201 O LEU C 487 -3.246 3.816 -71.339 1.00 66.48 O +ATOM 6202 CB LEU C 487 -4.287 1.349 -73.179 1.00 68.64 C +ATOM 6203 CG LEU C 487 -5.411 0.894 -74.108 1.00 60.99 C +ATOM 6204 CD1 LEU C 487 -5.889 -0.502 -73.743 1.00 57.79 C +ATOM 6205 CD2 LEU C 487 -6.555 1.896 -74.057 1.00 56.74 C +ATOM 6206 N GLN C 488 -1.539 2.866 -72.466 1.00 74.04 N +ATOM 6207 CA GLN C 488 -0.534 3.396 -71.549 1.00 72.44 C +ATOM 6208 C GLN C 488 -0.438 4.910 -71.672 1.00 69.41 C +ATOM 6209 O GLN C 488 -0.442 5.631 -70.668 1.00 70.48 O +ATOM 6210 CB GLN C 488 0.824 2.752 -71.831 1.00 70.27 C +ATOM 6211 CG GLN C 488 0.903 1.274 -71.487 1.00 74.28 C +ATOM 6212 CD GLN C 488 2.156 0.610 -72.031 1.00 77.32 C +ATOM 6213 OE1 GLN C 488 2.697 1.021 -73.063 1.00 77.11 O +ATOM 6214 NE2 GLN C 488 2.629 -0.417 -71.333 1.00 68.16 N +ATOM 6215 N LEU C 489 -0.380 5.406 -72.909 1.00 62.83 N +ATOM 6216 CA LEU C 489 -0.267 6.837 -73.149 1.00 58.28 C +ATOM 6217 C LEU C 489 -1.486 7.599 -72.645 1.00 63.24 C +ATOM 6218 O LEU C 489 -1.361 8.744 -72.195 1.00 67.45 O +ATOM 6219 CB LEU C 489 -0.076 7.079 -74.638 1.00 59.45 C +ATOM 6220 CG LEU C 489 0.208 8.523 -75.011 1.00 71.45 C +ATOM 6221 CD1 LEU C 489 1.633 8.880 -74.618 1.00 70.41 C +ATOM 6222 CD2 LEU C 489 -0.051 8.747 -76.491 1.00 77.64 C +ATOM 6223 N LEU C 490 -2.668 6.995 -72.728 1.00 63.49 N +ATOM 6224 CA LEU C 490 -3.896 7.624 -72.259 1.00 66.22 C +ATOM 6225 C LEU C 490 -4.079 7.547 -70.750 1.00 66.61 C +ATOM 6226 O LEU C 490 -5.157 7.890 -70.259 1.00 67.08 O +ATOM 6227 CB LEU C 490 -5.107 6.995 -72.949 1.00 70.55 C +ATOM 6228 CG LEU C 490 -5.481 7.519 -74.340 1.00 73.08 C +ATOM 6229 CD1 LEU C 490 -4.842 8.873 -74.600 1.00 79.17 C +ATOM 6230 CD2 LEU C 490 -5.123 6.526 -75.434 1.00 69.85 C +ATOM 6231 N ALA C 491 -3.074 7.102 -70.004 1.00 67.14 N +ATOM 6232 CA ALA C 491 -3.151 7.061 -68.553 1.00 62.76 C +ATOM 6233 C ALA C 491 -2.205 8.052 -67.899 1.00 75.29 C +ATOM 6234 O ALA C 491 -2.187 8.149 -66.668 1.00 81.69 O +ATOM 6235 CB ALA C 491 -2.859 5.646 -68.044 1.00 61.94 C +ATOM 6236 N LYS C 492 -1.436 8.801 -68.694 1.00 84.40 N +ATOM 6237 CA LYS C 492 -0.470 9.774 -68.193 1.00 82.63 C +ATOM 6238 C LYS C 492 -1.147 11.110 -67.918 1.00 87.43 C +ATOM 6239 O LYS C 492 -2.051 11.524 -68.649 1.00 91.53 O +ATOM 6240 CB LYS C 492 0.674 9.961 -69.195 1.00 64.01 C +ATOM 6241 CG LYS C 492 1.835 9.005 -68.986 1.00 60.84 C +ATOM 6242 CD LYS C 492 1.412 7.564 -69.170 1.00 62.75 C +ATOM 6243 CE LYS C 492 2.403 6.598 -68.530 1.00 74.95 C +ATOM 6244 NZ LYS C 492 1.868 5.202 -68.445 1.00 58.38 N +ATOM 6245 N GLU C 493 -0.695 11.788 -66.859 1.00 86.06 N +ATOM 6246 CA GLU C 493 -1.365 13.013 -66.432 1.00 91.71 C +ATOM 6247 C GLU C 493 -1.331 14.089 -67.513 1.00 93.15 C +ATOM 6248 O GLU C 493 -2.262 14.897 -67.607 1.00 94.21 O +ATOM 6249 CB GLU C 493 -0.737 13.530 -65.134 1.00 94.93 C +ATOM 6250 CG GLU C 493 -1.693 13.530 -63.941 1.00 93.41 C +ATOM 6251 CD GLU C 493 -2.760 14.611 -64.035 1.00 95.03 C +ATOM 6252 OE1 GLU C 493 -2.545 15.603 -64.768 1.00 89.33 O +ATOM 6253 OE2 GLU C 493 -3.818 14.462 -63.386 1.00 95.00 O +ATOM 6254 N GLU C 494 -0.290 14.102 -68.354 1.00 93.49 N +ATOM 6255 CA GLU C 494 -0.233 15.086 -69.431 1.00 92.50 C +ATOM 6256 C GLU C 494 -1.286 14.813 -70.494 1.00 91.82 C +ATOM 6257 O GLU C 494 -1.749 15.745 -71.162 1.00 96.77 O +ATOM 6258 CB GLU C 494 1.155 15.111 -70.072 1.00 85.60 C +ATOM 6259 CG GLU C 494 1.758 13.748 -70.368 1.00 80.62 C +ATOM 6260 CD GLU C 494 2.628 13.232 -69.236 1.00 88.53 C +ATOM 6261 OE1 GLU C 494 2.111 13.054 -68.110 1.00 83.16 O +ATOM 6262 OE2 GLU C 494 3.842 13.038 -69.470 1.00 94.04 O +ATOM 6263 N TYR C 495 -1.665 13.551 -70.674 1.00 88.98 N +ATOM 6264 CA TYR C 495 -2.695 13.193 -71.637 1.00 86.24 C +ATOM 6265 C TYR C 495 -3.954 12.729 -70.917 1.00 85.14 C +ATOM 6266 O TYR C 495 -4.908 13.500 -70.770 1.00 85.27 O +ATOM 6267 CB TYR C 495 -2.164 12.122 -72.588 1.00 75.88 C +ATOM 6268 CG TYR C 495 -1.134 12.657 -73.553 1.00 77.20 C +ATOM 6269 CD1 TYR C 495 -0.911 14.024 -73.679 1.00 85.62 C +ATOM 6270 CD2 TYR C 495 -0.361 11.800 -74.312 1.00 75.24 C +ATOM 6271 CE1 TYR C 495 0.037 14.518 -74.557 1.00 89.33 C +ATOM 6272 CE2 TYR C 495 0.593 12.280 -75.188 1.00 80.56 C +ATOM 6273 CZ TYR C 495 0.788 13.638 -75.309 1.00 87.23 C +ATOM 6274 OH TYR C 495 1.740 14.106 -76.187 1.00 81.89 O +ATOM 6275 N LYS C 496 -3.953 11.473 -70.466 1.00 83.08 N +ATOM 6276 CA LYS C 496 -5.021 10.880 -69.664 1.00 83.11 C +ATOM 6277 C LYS C 496 -6.357 10.905 -70.399 1.00 78.67 C +ATOM 6278 O LYS C 496 -6.462 11.430 -71.510 1.00 77.83 O +ATOM 6279 CB LYS C 496 -5.129 11.565 -68.290 1.00 84.25 C +ATOM 6280 CG LYS C 496 -6.195 12.645 -68.137 1.00 79.25 C +ATOM 6281 CD LYS C 496 -6.137 13.261 -66.745 1.00 83.24 C +ATOM 6282 CE LYS C 496 -6.142 12.186 -65.662 1.00 81.64 C +ATOM 6283 NZ LYS C 496 -5.984 12.748 -64.291 1.00 76.54 N +ATOM 6284 N LEU C 497 -7.380 10.306 -69.802 1.00 73.78 N +ATOM 6285 CA LEU C 497 -8.663 10.176 -70.470 1.00 69.85 C +ATOM 6286 C LEU C 497 -9.640 11.276 -70.095 1.00 66.73 C +ATOM 6287 O LEU C 497 -10.306 11.827 -70.975 1.00 68.70 O +ATOM 6288 CB LEU C 497 -9.276 8.810 -70.156 1.00 70.58 C +ATOM 6289 CG LEU C 497 -9.518 7.907 -71.363 1.00 60.50 C +ATOM 6290 CD1 LEU C 497 -10.797 8.307 -72.041 1.00 60.94 C +ATOM 6291 CD2 LEU C 497 -8.367 8.008 -72.334 1.00 56.01 C +ATOM 6292 N SER C 498 -9.731 11.616 -68.810 1.00 68.99 N +ATOM 6293 CA SER C 498 -10.719 12.597 -68.380 1.00 72.68 C +ATOM 6294 C SER C 498 -10.503 13.925 -69.091 1.00 76.45 C +ATOM 6295 O SER C 498 -11.430 14.475 -69.699 1.00 71.71 O +ATOM 6296 CB SER C 498 -10.657 12.771 -66.862 1.00 79.20 C +ATOM 6297 OG SER C 498 -9.388 13.250 -66.446 1.00 80.28 O +ATOM 6298 N SER C 499 -9.266 14.433 -69.058 1.00 83.23 N +ATOM 6299 CA SER C 499 -8.954 15.709 -69.698 1.00 88.38 C +ATOM 6300 C SER C 499 -9.070 15.624 -71.215 1.00 87.27 C +ATOM 6301 O SER C 499 -9.403 16.619 -71.870 1.00 84.98 O +ATOM 6302 CB SER C 499 -7.549 16.168 -69.295 1.00 90.33 C +ATOM 6303 OG SER C 499 -6.550 15.285 -69.783 1.00 88.73 O +ATOM 6304 N LEU C 500 -8.813 14.451 -71.788 1.00 80.43 N +ATOM 6305 CA LEU C 500 -9.009 14.279 -73.219 1.00 69.74 C +ATOM 6306 C LEU C 500 -10.479 14.113 -73.567 1.00 69.07 C +ATOM 6307 O LEU C 500 -10.912 14.555 -74.636 1.00 72.55 O +ATOM 6308 CB LEU C 500 -8.213 13.074 -73.710 1.00 59.71 C +ATOM 6309 CG LEU C 500 -6.764 13.422 -74.022 1.00 68.98 C +ATOM 6310 CD1 LEU C 500 -6.001 12.202 -74.477 1.00 66.92 C +ATOM 6311 CD2 LEU C 500 -6.725 14.502 -75.075 1.00 78.29 C +ATOM 6312 N MET C 501 -11.260 13.501 -72.678 1.00 67.65 N +ATOM 6313 CA MET C 501 -12.660 13.251 -72.990 1.00 66.29 C +ATOM 6314 C MET C 501 -13.522 14.479 -72.739 1.00 65.21 C +ATOM 6315 O MET C 501 -14.424 14.771 -73.528 1.00 64.96 O +ATOM 6316 CB MET C 501 -13.168 12.051 -72.191 1.00 70.63 C +ATOM 6317 CG MET C 501 -14.494 11.464 -72.669 1.00 67.60 C +ATOM 6318 SD MET C 501 -14.486 10.672 -74.305 1.00 67.24 S +ATOM 6319 CE MET C 501 -12.792 10.097 -74.473 1.00 55.49 C +ATOM 6320 N GLU C 502 -13.273 15.212 -71.652 1.00 70.49 N +ATOM 6321 CA GLU C 502 -14.035 16.437 -71.438 1.00 78.27 C +ATOM 6322 C GLU C 502 -13.680 17.514 -72.456 1.00 80.57 C +ATOM 6323 O GLU C 502 -14.480 18.431 -72.675 1.00 78.36 O +ATOM 6324 CB GLU C 502 -13.820 16.964 -70.019 1.00 75.84 C +ATOM 6325 CG GLU C 502 -12.459 17.587 -69.783 1.00 68.25 C +ATOM 6326 CD GLU C 502 -12.335 18.193 -68.401 1.00 69.73 C +ATOM 6327 OE1 GLU C 502 -13.356 18.268 -67.680 1.00 64.58 O +ATOM 6328 OE2 GLU C 502 -11.211 18.596 -68.038 1.00 68.08 O +ATOM 6329 N GLU C 503 -12.513 17.417 -73.095 1.00 75.32 N +ATOM 6330 CA GLU C 503 -12.169 18.363 -74.150 1.00 75.16 C +ATOM 6331 C GLU C 503 -13.102 18.196 -75.341 1.00 73.77 C +ATOM 6332 O GLU C 503 -13.859 19.110 -75.686 1.00 72.77 O +ATOM 6333 CB GLU C 503 -10.712 18.171 -74.580 1.00 85.34 C +ATOM 6334 CG GLU C 503 -10.322 18.945 -75.840 1.00 94.92 C +ATOM 6335 CD GLU C 503 -9.552 20.230 -75.552 1.00110.75 C +ATOM 6336 OE1 GLU C 503 -8.373 20.149 -75.133 1.00 98.13 O +ATOM 6337 OE2 GLU C 503 -10.127 21.323 -75.749 1.00120.47 O +ATOM 6338 N SER C 504 -13.090 17.011 -75.959 1.00 68.67 N +ATOM 6339 CA SER C 504 -13.878 16.803 -77.170 1.00 68.25 C +ATOM 6340 C SER C 504 -15.375 16.765 -76.874 1.00 62.87 C +ATOM 6341 O SER C 504 -16.173 17.311 -77.645 1.00 68.47 O +ATOM 6342 CB SER C 504 -13.419 15.529 -77.878 1.00 54.39 C +ATOM 6343 OG SER C 504 -13.486 14.412 -77.017 1.00 52.47 O +ATOM 6344 N LEU C 505 -15.779 16.162 -75.753 1.00 58.07 N +ATOM 6345 CA LEU C 505 -17.191 16.181 -75.388 1.00 62.77 C +ATOM 6346 C LEU C 505 -17.689 17.592 -75.138 1.00 71.36 C +ATOM 6347 O LEU C 505 -18.903 17.829 -75.162 1.00 70.08 O +ATOM 6348 CB LEU C 505 -17.432 15.338 -74.139 1.00 67.05 C +ATOM 6349 CG LEU C 505 -17.331 13.827 -74.315 1.00 66.40 C +ATOM 6350 CD1 LEU C 505 -17.601 13.116 -73.002 1.00 67.10 C +ATOM 6351 CD2 LEU C 505 -18.294 13.361 -75.388 1.00 61.64 C +ATOM 6352 N LEU C 506 -16.775 18.537 -74.913 1.00 72.01 N +ATOM 6353 CA LEU C 506 -17.172 19.924 -74.736 1.00 78.13 C +ATOM 6354 C LEU C 506 -17.639 20.548 -76.044 1.00 69.69 C +ATOM 6355 O LEU C 506 -18.317 21.580 -76.020 1.00 77.82 O +ATOM 6356 CB LEU C 506 -16.007 20.723 -74.142 1.00 81.44 C +ATOM 6357 CG LEU C 506 -16.283 22.109 -73.554 1.00 84.89 C +ATOM 6358 CD1 LEU C 506 -17.125 21.991 -72.295 1.00 63.56 C +ATOM 6359 CD2 LEU C 506 -14.978 22.858 -73.273 1.00 79.59 C +ATOM 6360 N GLN C 507 -17.329 19.932 -77.179 1.00 60.04 N +ATOM 6361 CA GLN C 507 -17.771 20.457 -78.464 1.00 68.93 C +ATOM 6362 C GLN C 507 -19.020 19.695 -78.913 1.00 69.33 C +ATOM 6363 O GLN C 507 -19.004 18.868 -79.823 1.00 78.26 O +ATOM 6364 CB GLN C 507 -16.637 20.389 -79.487 1.00 62.93 C +ATOM 6365 CG GLN C 507 -16.986 20.927 -80.874 1.00 71.59 C +ATOM 6366 CD GLN C 507 -17.749 22.252 -80.850 1.00 84.04 C +ATOM 6367 OE1 GLN C 507 -17.368 23.201 -80.159 1.00 86.16 O +ATOM 6368 NE2 GLN C 507 -18.841 22.313 -81.609 1.00 80.80 N +ATOM 6369 N ASP C 508 -20.120 19.976 -78.218 1.00 61.87 N +ATOM 6370 CA ASP C 508 -21.414 19.407 -78.565 1.00 61.70 C +ATOM 6371 C ASP C 508 -22.505 20.242 -77.916 1.00 64.61 C +ATOM 6372 O ASP C 508 -22.382 20.629 -76.751 1.00 69.03 O +ATOM 6373 CB ASP C 508 -21.532 17.945 -78.116 1.00 62.76 C +ATOM 6374 CG ASP C 508 -22.701 17.224 -78.776 1.00 66.11 C +ATOM 6375 OD1 ASP C 508 -23.348 17.820 -79.663 1.00 67.55 O +ATOM 6376 OD2 ASP C 508 -22.976 16.061 -78.411 1.00 64.95 O +ATOM 6377 N ARG C 509 -23.579 20.500 -78.664 1.00 60.21 N +ATOM 6378 CA ARG C 509 -24.686 21.288 -78.133 1.00 59.67 C +ATOM 6379 C ARG C 509 -25.454 20.484 -77.093 1.00 63.37 C +ATOM 6380 O ARG C 509 -26.686 20.530 -77.043 1.00 71.44 O +ATOM 6381 CB ARG C 509 -25.629 21.736 -79.250 1.00 67.89 C +ATOM 6382 CG ARG C 509 -26.533 22.904 -78.870 1.00 68.71 C +ATOM 6383 CD ARG C 509 -27.881 22.794 -79.558 1.00 70.64 C +ATOM 6384 NE ARG C 509 -28.903 23.591 -78.889 1.00 68.15 N +ATOM 6385 CZ ARG C 509 -29.126 24.878 -79.137 1.00 73.79 C +ATOM 6386 NH1 ARG C 509 -30.077 25.524 -78.479 1.00 78.05 N +ATOM 6387 NH2 ARG C 509 -28.398 25.521 -80.041 1.00 75.80 N +ATOM 6388 N LEU C 510 -24.735 19.739 -76.264 1.00 64.25 N +ATOM 6389 CA LEU C 510 -25.361 18.934 -75.232 1.00 69.24 C +ATOM 6390 C LEU C 510 -24.546 18.898 -73.947 1.00 72.18 C +ATOM 6391 O LEU C 510 -25.009 18.317 -72.960 1.00 69.68 O +ATOM 6392 CB LEU C 510 -25.599 17.506 -75.749 1.00 61.28 C +ATOM 6393 CG LEU C 510 -27.044 16.993 -75.718 1.00 62.79 C +ATOM 6394 CD1 LEU C 510 -27.633 17.239 -74.348 1.00 62.18 C +ATOM 6395 CD2 LEU C 510 -27.926 17.614 -76.793 1.00 52.73 C +ATOM 6396 N VAL C 511 -23.362 19.509 -73.929 1.00 72.55 N +ATOM 6397 CA VAL C 511 -22.458 19.503 -72.773 1.00 72.40 C +ATOM 6398 C VAL C 511 -23.192 20.043 -71.546 1.00 72.03 C +ATOM 6399 O VAL C 511 -24.035 20.954 -71.681 1.00 73.18 O +ATOM 6400 CB VAL C 511 -21.187 20.322 -73.091 1.00 67.82 C +ATOM 6401 CG1 VAL C 511 -21.455 21.829 -73.079 1.00 64.50 C +ATOM 6402 CG2 VAL C 511 -20.023 19.944 -72.177 1.00 63.26 C +ATOM 6403 N PRO C 512 -22.979 19.484 -70.338 1.00 67.15 N +ATOM 6404 CA PRO C 512 -22.104 18.339 -70.075 1.00 60.89 C +ATOM 6405 C PRO C 512 -22.798 17.038 -70.449 1.00 73.56 C +ATOM 6406 O PRO C 512 -23.808 16.678 -69.839 1.00 77.42 O +ATOM 6407 CB PRO C 512 -21.844 18.425 -68.564 1.00 49.27 C +ATOM 6408 CG PRO C 512 -22.495 19.715 -68.103 1.00 58.31 C +ATOM 6409 CD PRO C 512 -23.572 19.994 -69.095 1.00 58.43 C +ATOM 6410 N VAL C 513 -22.276 16.354 -71.469 1.00 67.25 N +ATOM 6411 CA VAL C 513 -22.881 15.092 -71.872 1.00 61.03 C +ATOM 6412 C VAL C 513 -22.630 14.026 -70.820 1.00 59.06 C +ATOM 6413 O VAL C 513 -23.467 13.141 -70.605 1.00 57.76 O +ATOM 6414 CB VAL C 513 -22.353 14.676 -73.256 1.00 61.19 C +ATOM 6415 CG1 VAL C 513 -22.639 15.769 -74.269 1.00 67.17 C +ATOM 6416 CG2 VAL C 513 -20.868 14.416 -73.197 1.00 50.10 C +ATOM 6417 N LEU C 514 -21.503 14.115 -70.120 1.00 56.75 N +ATOM 6418 CA LEU C 514 -21.147 13.190 -69.055 1.00 60.33 C +ATOM 6419 C LEU C 514 -20.934 13.983 -67.777 1.00 64.92 C +ATOM 6420 O LEU C 514 -20.107 14.901 -67.746 1.00 64.52 O +ATOM 6421 CB LEU C 514 -19.883 12.403 -69.403 1.00 55.20 C +ATOM 6422 CG LEU C 514 -19.996 11.290 -70.441 1.00 52.73 C +ATOM 6423 CD1 LEU C 514 -18.662 10.570 -70.548 1.00 51.17 C +ATOM 6424 CD2 LEU C 514 -21.119 10.322 -70.087 1.00 49.10 C +ATOM 6425 N ILE C 515 -21.683 13.632 -66.730 1.00 63.90 N +ATOM 6426 CA ILE C 515 -21.397 14.180 -65.415 1.00 65.14 C +ATOM 6427 C ILE C 515 -19.962 13.800 -65.039 1.00 65.12 C +ATOM 6428 O ILE C 515 -19.416 12.795 -65.511 1.00 67.50 O +ATOM 6429 CB ILE C 515 -22.417 13.675 -64.379 1.00 69.82 C +ATOM 6430 CG1 ILE C 515 -22.368 14.523 -63.110 1.00 82.08 C +ATOM 6431 CG2 ILE C 515 -22.162 12.222 -64.033 1.00 72.82 C +ATOM 6432 CD1 ILE C 515 -22.782 15.959 -63.325 1.00 95.39 C +ATOM 6433 N LYS C 516 -19.334 14.633 -64.214 1.00 69.22 N +ATOM 6434 CA LYS C 516 -17.901 14.485 -63.957 1.00 76.97 C +ATOM 6435 C LYS C 516 -17.479 13.122 -63.405 1.00 74.37 C +ATOM 6436 O LYS C 516 -16.388 12.656 -63.779 1.00 67.45 O +ATOM 6437 CB LYS C 516 -17.433 15.613 -63.026 1.00 84.66 C +ATOM 6438 CG LYS C 516 -15.917 15.764 -62.956 1.00 78.54 C +ATOM 6439 CD LYS C 516 -15.495 17.041 -62.245 1.00 71.70 C +ATOM 6440 CE LYS C 516 -13.984 17.227 -62.336 1.00 75.74 C +ATOM 6441 NZ LYS C 516 -13.516 18.511 -61.747 1.00 73.41 N +ATOM 6442 N PRO C 517 -18.245 12.446 -62.531 1.00 76.33 N +ATOM 6443 CA PRO C 517 -17.811 11.114 -62.063 1.00 73.20 C +ATOM 6444 C PRO C 517 -17.495 10.125 -63.175 1.00 70.70 C +ATOM 6445 O PRO C 517 -16.558 9.327 -63.042 1.00 58.94 O +ATOM 6446 CB PRO C 517 -19.009 10.647 -61.227 1.00 72.76 C +ATOM 6447 CG PRO C 517 -19.584 11.900 -60.690 1.00 71.06 C +ATOM 6448 CD PRO C 517 -19.418 12.924 -61.772 1.00 72.12 C +ATOM 6449 N HIS C 518 -18.247 10.168 -64.278 1.00 75.51 N +ATOM 6450 CA HIS C 518 -17.999 9.251 -65.385 1.00 61.48 C +ATOM 6451 C HIS C 518 -16.693 9.583 -66.088 1.00 58.55 C +ATOM 6452 O HIS C 518 -15.924 8.682 -66.440 1.00 55.38 O +ATOM 6453 CB HIS C 518 -19.153 9.307 -66.386 1.00 51.19 C +ATOM 6454 CG HIS C 518 -20.417 8.672 -65.899 1.00 45.81 C +ATOM 6455 ND1 HIS C 518 -21.557 9.397 -65.624 1.00 50.06 N +ATOM 6456 CD2 HIS C 518 -20.727 7.379 -65.656 1.00 50.89 C +ATOM 6457 CE1 HIS C 518 -22.513 8.578 -65.225 1.00 51.09 C +ATOM 6458 NE2 HIS C 518 -22.034 7.347 -65.234 1.00 58.46 N +ATOM 6459 N LEU C 519 -16.428 10.874 -66.298 1.00 66.37 N +ATOM 6460 CA LEU C 519 -15.189 11.283 -66.952 1.00 75.81 C +ATOM 6461 C LEU C 519 -13.969 10.848 -66.148 1.00 69.51 C +ATOM 6462 O LEU C 519 -12.934 10.480 -66.719 1.00 55.95 O +ATOM 6463 CB LEU C 519 -15.193 12.799 -67.164 1.00 69.70 C +ATOM 6464 CG LEU C 519 -16.242 13.327 -68.149 1.00 64.14 C +ATOM 6465 CD1 LEU C 519 -16.409 14.824 -68.002 1.00 71.84 C +ATOM 6466 CD2 LEU C 519 -15.876 12.977 -69.585 1.00 65.31 C +ATOM 6467 N GLU C 520 -14.071 10.889 -64.819 1.00 75.33 N +ATOM 6468 CA GLU C 520 -12.953 10.487 -63.975 1.00 75.26 C +ATOM 6469 C GLU C 520 -12.861 8.970 -63.855 1.00 65.88 C +ATOM 6470 O GLU C 520 -11.753 8.423 -63.774 1.00 57.36 O +ATOM 6471 CB GLU C 520 -13.075 11.146 -62.601 1.00 75.91 C +ATOM 6472 CG GLU C 520 -11.815 11.059 -61.756 1.00 71.29 C +ATOM 6473 CD GLU C 520 -12.000 11.670 -60.383 1.00 79.28 C +ATOM 6474 OE1 GLU C 520 -12.994 12.404 -60.192 1.00 87.59 O +ATOM 6475 OE2 GLU C 520 -11.140 11.440 -59.504 1.00 73.55 O +ATOM 6476 N ALA C 521 -14.010 8.284 -63.851 1.00 69.52 N +ATOM 6477 CA ALA C 521 -14.016 6.825 -63.832 1.00 64.83 C +ATOM 6478 C ALA C 521 -13.320 6.250 -65.057 1.00 53.90 C +ATOM 6479 O ALA C 521 -12.802 5.130 -65.006 1.00 48.59 O +ATOM 6480 CB ALA C 521 -15.454 6.310 -63.747 1.00 59.56 C +ATOM 6481 N LEU C 522 -13.299 7.002 -66.160 1.00 57.47 N +ATOM 6482 CA LEU C 522 -12.611 6.544 -67.361 1.00 57.16 C +ATOM 6483 C LEU C 522 -11.149 6.235 -67.067 1.00 61.40 C +ATOM 6484 O LEU C 522 -10.604 5.244 -67.567 1.00 57.82 O +ATOM 6485 CB LEU C 522 -12.729 7.598 -68.459 1.00 52.41 C +ATOM 6486 CG LEU C 522 -13.479 7.212 -69.731 1.00 49.05 C +ATOM 6487 CD1 LEU C 522 -14.640 6.294 -69.425 1.00 48.77 C +ATOM 6488 CD2 LEU C 522 -13.987 8.471 -70.389 1.00 58.34 C +ATOM 6489 N ASP C 523 -10.494 7.077 -66.260 1.00 67.25 N +ATOM 6490 CA ASP C 523 -9.121 6.792 -65.858 1.00 63.65 C +ATOM 6491 C ASP C 523 -9.066 5.602 -64.916 1.00 57.00 C +ATOM 6492 O ASP C 523 -8.072 4.867 -64.897 1.00 55.90 O +ATOM 6493 CB ASP C 523 -8.484 8.010 -65.184 1.00 65.85 C +ATOM 6494 CG ASP C 523 -8.389 9.212 -66.104 1.00 68.81 C +ATOM 6495 OD1 ASP C 523 -9.380 9.967 -66.194 1.00 63.11 O +ATOM 6496 OD2 ASP C 523 -7.335 9.390 -66.753 1.00 70.91 O +ATOM 6497 N ARG C 524 -10.112 5.417 -64.110 1.00 58.94 N +ATOM 6498 CA ARG C 524 -10.137 4.299 -63.178 1.00 62.70 C +ATOM 6499 C ARG C 524 -10.315 2.972 -63.910 1.00 63.62 C +ATOM 6500 O ARG C 524 -9.586 2.008 -63.646 1.00 61.61 O +ATOM 6501 CB ARG C 524 -11.249 4.513 -62.151 1.00 52.18 C +ATOM 6502 CG ARG C 524 -11.417 3.367 -61.185 1.00 50.81 C +ATOM 6503 CD ARG C 524 -12.576 3.601 -60.252 1.00 50.97 C +ATOM 6504 NE ARG C 524 -13.800 3.909 -60.984 1.00 60.09 N +ATOM 6505 CZ ARG C 524 -14.994 4.061 -60.417 1.00 70.56 C +ATOM 6506 NH1 ARG C 524 -15.132 3.925 -59.104 1.00 74.59 N +ATOM 6507 NH2 ARG C 524 -16.054 4.340 -61.166 1.00 66.53 N +ATOM 6508 N ARG C 525 -11.256 2.909 -64.859 1.00 59.78 N +ATOM 6509 CA ARG C 525 -11.425 1.684 -65.632 1.00 50.63 C +ATOM 6510 C ARG C 525 -10.228 1.428 -66.537 1.00 51.72 C +ATOM 6511 O ARG C 525 -9.884 0.269 -66.790 1.00 54.71 O +ATOM 6512 CB ARG C 525 -12.710 1.748 -66.462 1.00 49.48 C +ATOM 6513 CG ARG C 525 -13.996 1.589 -65.664 1.00 49.82 C +ATOM 6514 CD ARG C 525 -14.819 2.871 -65.707 1.00 51.58 C +ATOM 6515 NE ARG C 525 -16.022 2.814 -64.879 1.00 54.48 N +ATOM 6516 CZ ARG C 525 -17.252 2.651 -65.352 1.00 49.65 C +ATOM 6517 NH1 ARG C 525 -17.450 2.528 -66.654 1.00 55.49 N +ATOM 6518 NH2 ARG C 525 -18.285 2.618 -64.524 1.00 51.16 N +ATOM 6519 N LEU C 526 -9.567 2.486 -67.010 1.00 52.98 N +ATOM 6520 CA LEU C 526 -8.436 2.298 -67.913 1.00 54.85 C +ATOM 6521 C LEU C 526 -7.254 1.658 -67.199 1.00 59.95 C +ATOM 6522 O LEU C 526 -6.607 0.754 -67.743 1.00 59.90 O +ATOM 6523 CB LEU C 526 -8.028 3.633 -68.535 1.00 52.92 C +ATOM 6524 CG LEU C 526 -6.731 3.628 -69.348 1.00 60.55 C +ATOM 6525 CD1 LEU C 526 -6.781 2.613 -70.483 1.00 59.73 C +ATOM 6526 CD2 LEU C 526 -6.452 5.018 -69.884 1.00 64.52 C +ATOM 6527 N ARG C 527 -6.957 2.104 -65.980 1.00 62.48 N +ATOM 6528 CA ARG C 527 -5.807 1.553 -65.278 1.00 64.12 C +ATOM 6529 C ARG C 527 -6.032 0.098 -64.900 1.00 68.36 C +ATOM 6530 O ARG C 527 -5.068 -0.672 -64.813 1.00 71.37 O +ATOM 6531 CB ARG C 527 -5.499 2.401 -64.046 1.00 68.04 C +ATOM 6532 CG ARG C 527 -6.576 2.384 -62.983 1.00 72.97 C +ATOM 6533 CD ARG C 527 -5.952 2.430 -61.603 1.00 91.40 C +ATOM 6534 NE ARG C 527 -6.925 2.739 -60.560 1.00 94.39 N +ATOM 6535 CZ ARG C 527 -7.261 3.974 -60.199 1.00 87.61 C +ATOM 6536 NH1 ARG C 527 -6.710 5.020 -60.808 1.00 69.55 N +ATOM 6537 NH2 ARG C 527 -8.153 4.165 -59.234 1.00 83.26 N +ATOM 6538 N LEU C 528 -7.291 -0.315 -64.741 1.00 69.71 N +ATOM 6539 CA LEU C 528 -7.559 -1.724 -64.477 1.00 70.11 C +ATOM 6540 C LEU C 528 -7.326 -2.563 -65.728 1.00 65.63 C +ATOM 6541 O LEU C 528 -6.752 -3.654 -65.648 1.00 65.99 O +ATOM 6542 CB LEU C 528 -8.986 -1.898 -63.957 1.00 62.82 C +ATOM 6543 CG LEU C 528 -9.309 -1.120 -62.676 1.00 56.66 C +ATOM 6544 CD1 LEU C 528 -10.700 -1.479 -62.149 1.00 49.77 C +ATOM 6545 CD2 LEU C 528 -8.235 -1.305 -61.609 1.00 55.11 C +ATOM 6546 N VAL C 529 -7.739 -2.057 -66.895 1.00 61.23 N +ATOM 6547 CA VAL C 529 -7.408 -2.725 -68.153 1.00 62.67 C +ATOM 6548 C VAL C 529 -5.902 -2.767 -68.337 1.00 69.21 C +ATOM 6549 O VAL C 529 -5.337 -3.784 -68.759 1.00 70.10 O +ATOM 6550 CB VAL C 529 -8.089 -2.023 -69.342 1.00 56.68 C +ATOM 6551 CG1 VAL C 529 -7.542 -2.563 -70.662 1.00 49.91 C +ATOM 6552 CG2 VAL C 529 -9.584 -2.206 -69.271 1.00 54.54 C +ATOM 6553 N LEU C 530 -5.232 -1.653 -68.039 1.00 68.62 N +ATOM 6554 CA LEU C 530 -3.782 -1.617 -68.144 1.00 70.24 C +ATOM 6555 C LEU C 530 -3.134 -2.606 -67.184 1.00 74.11 C +ATOM 6556 O LEU C 530 -2.110 -3.216 -67.517 1.00 71.83 O +ATOM 6557 CB LEU C 530 -3.284 -0.197 -67.881 1.00 61.42 C +ATOM 6558 CG LEU C 530 -2.143 0.283 -68.777 1.00 70.56 C +ATOM 6559 CD1 LEU C 530 -2.451 0.013 -70.241 1.00 67.05 C +ATOM 6560 CD2 LEU C 530 -1.889 1.760 -68.548 1.00 74.01 C +ATOM 6561 N LYS C 531 -3.728 -2.798 -66.005 1.00 69.14 N +ATOM 6562 CA LYS C 531 -3.155 -3.716 -65.027 1.00 73.07 C +ATOM 6563 C LYS C 531 -3.412 -5.173 -65.395 1.00 76.33 C +ATOM 6564 O LYS C 531 -2.545 -6.027 -65.180 1.00 81.07 O +ATOM 6565 CB LYS C 531 -3.706 -3.408 -63.636 1.00 78.07 C +ATOM 6566 CG LYS C 531 -3.038 -4.194 -62.524 1.00 90.92 C +ATOM 6567 CD LYS C 531 -1.561 -3.830 -62.415 1.00 88.18 C +ATOM 6568 CE LYS C 531 -1.363 -2.443 -61.816 1.00 74.34 C +ATOM 6569 NZ LYS C 531 0.080 -2.097 -61.698 1.00 67.11 N +ATOM 6570 N VAL C 532 -4.590 -5.476 -65.950 1.00 75.48 N +ATOM 6571 CA VAL C 532 -4.880 -6.841 -66.389 1.00 71.81 C +ATOM 6572 C VAL C 532 -3.913 -7.272 -67.485 1.00 71.22 C +ATOM 6573 O VAL C 532 -3.520 -8.444 -67.555 1.00 72.95 O +ATOM 6574 CB VAL C 532 -6.354 -6.957 -66.838 1.00 60.74 C +ATOM 6575 CG1 VAL C 532 -6.591 -8.255 -67.582 1.00 64.38 C +ATOM 6576 CG2 VAL C 532 -7.278 -6.888 -65.637 1.00 50.83 C +ATOM 6577 N LEU C 533 -3.505 -6.338 -68.347 1.00 66.78 N +ATOM 6578 CA LEU C 533 -2.476 -6.643 -69.335 1.00 70.49 C +ATOM 6579 C LEU C 533 -1.126 -6.880 -68.675 1.00 81.55 C +ATOM 6580 O LEU C 533 -0.332 -7.697 -69.157 1.00 83.53 O +ATOM 6581 CB LEU C 533 -2.382 -5.516 -70.359 1.00 68.03 C +ATOM 6582 CG LEU C 533 -3.676 -5.267 -71.123 1.00 65.82 C +ATOM 6583 CD1 LEU C 533 -3.491 -4.173 -72.153 1.00 66.59 C +ATOM 6584 CD2 LEU C 533 -4.139 -6.549 -71.780 1.00 54.88 C +ATOM 6585 N SER C 534 -0.847 -6.170 -67.587 1.00 84.01 N +ATOM 6586 CA SER C 534 0.421 -6.327 -66.886 1.00 87.42 C +ATOM 6587 C SER C 534 0.446 -7.617 -66.069 1.00 89.75 C +ATOM 6588 O SER C 534 1.424 -8.374 -66.116 1.00 84.86 O +ATOM 6589 CB SER C 534 0.654 -5.113 -65.985 1.00 87.02 C +ATOM 6590 OG SER C 534 0.574 -3.907 -66.731 1.00 78.59 O +ATOM 6591 N ASP C 535 -0.633 -7.882 -65.321 1.00 94.03 N +ATOM 6592 CA ASP C 535 -0.732 -9.090 -64.504 1.00 95.02 C +ATOM 6593 C ASP C 535 -0.732 -10.363 -65.336 1.00 92.23 C +ATOM 6594 O ASP C 535 -0.460 -11.441 -64.796 1.00 95.14 O +ATOM 6595 CB ASP C 535 -2.000 -9.058 -63.645 1.00 86.45 C +ATOM 6596 CG ASP C 535 -1.983 -7.940 -62.619 1.00 95.33 C +ATOM 6597 OD1 ASP C 535 -0.884 -7.584 -62.139 1.00 90.90 O +ATOM 6598 OD2 ASP C 535 -3.073 -7.435 -62.275 1.00 98.05 O +ATOM 6599 N CYS C 536 -1.042 -10.268 -66.626 1.00 90.59 N +ATOM 6600 CA CYS C 536 -1.082 -11.444 -67.480 1.00 95.36 C +ATOM 6601 C CYS C 536 0.163 -11.593 -68.335 1.00 93.12 C +ATOM 6602 O CYS C 536 0.572 -12.721 -68.631 1.00 96.07 O +ATOM 6603 CB CYS C 536 -2.313 -11.400 -68.392 1.00 85.70 C +ATOM 6604 SG CYS C 536 -2.831 -13.047 -68.872 1.00129.41 S +ATOM 6605 N VAL C 537 0.782 -10.482 -68.736 1.00 92.66 N +ATOM 6606 CA VAL C 537 2.020 -10.579 -69.489 1.00 94.51 C +ATOM 6607 C VAL C 537 3.156 -11.132 -68.636 1.00 98.70 C +ATOM 6608 O VAL C 537 4.167 -11.584 -69.183 1.00 95.23 O +ATOM 6609 CB VAL C 537 2.391 -9.210 -70.085 1.00 96.12 C +ATOM 6610 CG1 VAL C 537 3.007 -8.301 -69.022 1.00100.25 C +ATOM 6611 CG2 VAL C 537 3.319 -9.399 -71.265 1.00 90.15 C +ATOM 6612 N GLU C 538 3.022 -11.120 -67.308 1.00 98.38 N +ATOM 6613 CA GLU C 538 4.005 -11.782 -66.460 1.00 98.59 C +ATOM 6614 C GLU C 538 3.776 -13.283 -66.365 1.00 98.38 C +ATOM 6615 O GLU C 538 4.668 -14.000 -65.897 1.00 97.57 O +ATOM 6616 CB GLU C 538 3.997 -11.195 -65.049 1.00 98.10 C +ATOM 6617 CG GLU C 538 2.783 -11.592 -64.234 1.00109.19 C +ATOM 6618 CD GLU C 538 2.860 -11.119 -62.794 1.00121.13 C +ATOM 6619 OE1 GLU C 538 2.792 -11.975 -61.885 1.00121.14 O +ATOM 6620 OE2 GLU C 538 3.003 -9.896 -62.574 1.00122.22 O +ATOM 6621 N LYS C 539 2.609 -13.770 -66.797 1.00 98.61 N +ATOM 6622 CA LYS C 539 2.294 -15.190 -66.762 1.00 94.92 C +ATOM 6623 C LYS C 539 2.315 -15.844 -68.133 1.00 87.21 C +ATOM 6624 O LYS C 539 2.400 -17.073 -68.208 1.00 95.64 O +ATOM 6625 CB LYS C 539 0.912 -15.413 -66.124 1.00 94.76 C +ATOM 6626 CG LYS C 539 0.852 -15.016 -64.651 1.00 99.68 C +ATOM 6627 CD LYS C 539 -0.509 -15.281 -64.021 1.00 96.18 C +ATOM 6628 CE LYS C 539 -0.518 -14.842 -62.558 1.00 80.66 C +ATOM 6629 NZ LYS C 539 -1.852 -15.017 -61.918 1.00 72.40 N +ATOM 6630 N ASP C 540 2.264 -15.060 -69.209 1.00 78.62 N +ATOM 6631 CA ASP C 540 2.401 -15.579 -70.559 1.00 78.28 C +ATOM 6632 C ASP C 540 3.527 -14.919 -71.344 1.00 80.23 C +ATOM 6633 O ASP C 540 3.908 -15.443 -72.398 1.00 71.01 O +ATOM 6634 CB ASP C 540 1.078 -15.433 -71.333 1.00 92.83 C +ATOM 6635 CG ASP C 540 0.034 -16.483 -70.934 1.00 91.41 C +ATOM 6636 OD1 ASP C 540 0.424 -17.629 -70.622 1.00 86.46 O +ATOM 6637 OD2 ASP C 540 -1.178 -16.166 -70.941 1.00 81.69 O +ATOM 6638 N GLY C 541 4.075 -13.807 -70.862 1.00 85.16 N +ATOM 6639 CA GLY C 541 5.191 -13.143 -71.506 1.00 89.90 C +ATOM 6640 C GLY C 541 4.766 -12.257 -72.665 1.00 91.79 C +ATOM 6641 O GLY C 541 3.713 -12.432 -73.275 1.00 91.51 O +ATOM 6642 N PHE C 542 5.615 -11.275 -72.966 1.00 89.66 N +ATOM 6643 CA PHE C 542 5.417 -10.456 -74.155 1.00 87.86 C +ATOM 6644 C PHE C 542 5.612 -11.310 -75.406 1.00 89.19 C +ATOM 6645 O PHE C 542 5.923 -12.504 -75.338 1.00 94.88 O +ATOM 6646 CB PHE C 542 6.371 -9.262 -74.165 1.00 98.36 C +ATOM 6647 CG PHE C 542 6.051 -8.210 -73.136 1.00111.96 C +ATOM 6648 CD1 PHE C 542 6.496 -8.342 -71.827 1.00118.17 C +ATOM 6649 CD2 PHE C 542 5.323 -7.078 -73.482 1.00 98.51 C +ATOM 6650 CE1 PHE C 542 6.206 -7.372 -70.877 1.00115.82 C +ATOM 6651 CE2 PHE C 542 5.031 -6.104 -72.537 1.00 99.02 C +ATOM 6652 CZ PHE C 542 5.473 -6.252 -71.234 1.00106.42 C +ATOM 6653 N SER C 543 5.391 -10.692 -76.569 1.00 87.75 N +ATOM 6654 CA SER C 543 5.478 -11.363 -77.866 1.00 94.50 C +ATOM 6655 C SER C 543 4.424 -12.462 -78.006 1.00 94.29 C +ATOM 6656 O SER C 543 3.950 -12.733 -79.114 1.00 99.02 O +ATOM 6657 CB SER C 543 6.883 -11.935 -78.094 1.00 97.69 C +ATOM 6658 OG SER C 543 7.860 -10.907 -78.105 1.00103.94 O +ATOM 6659 N ALA C 544 4.047 -13.094 -76.893 1.00 94.41 N +ATOM 6660 CA ALA C 544 2.939 -14.037 -76.831 1.00 93.73 C +ATOM 6661 C ALA C 544 1.667 -13.412 -76.274 1.00 82.47 C +ATOM 6662 O ALA C 544 0.631 -14.083 -76.214 1.00 75.46 O +ATOM 6663 CB ALA C 544 3.326 -15.252 -75.980 1.00 95.37 C +ATOM 6664 N VAL C 545 1.725 -12.149 -75.850 1.00 80.01 N +ATOM 6665 CA VAL C 545 0.544 -11.390 -75.473 1.00 75.02 C +ATOM 6666 C VAL C 545 0.310 -10.212 -76.409 1.00 75.48 C +ATOM 6667 O VAL C 545 -0.829 -9.942 -76.803 1.00 73.15 O +ATOM 6668 CB VAL C 545 0.637 -10.914 -74.006 1.00 74.21 C +ATOM 6669 CG1 VAL C 545 -0.416 -9.863 -73.704 1.00 63.62 C +ATOM 6670 CG2 VAL C 545 0.482 -12.097 -73.062 1.00 84.51 C +ATOM 6671 N VAL C 546 1.374 -9.536 -76.828 1.00 81.61 N +ATOM 6672 CA VAL C 546 1.284 -8.406 -77.744 1.00 78.39 C +ATOM 6673 C VAL C 546 1.749 -8.858 -79.119 1.00 76.49 C +ATOM 6674 O VAL C 546 2.818 -9.467 -79.258 1.00 75.37 O +ATOM 6675 CB VAL C 546 2.100 -7.201 -77.245 1.00 86.54 C +ATOM 6676 CG1 VAL C 546 1.353 -6.501 -76.129 1.00 76.82 C +ATOM 6677 CG2 VAL C 546 3.482 -7.645 -76.752 1.00 92.61 C +ATOM 6678 N GLU C 547 0.924 -8.607 -80.124 1.00 79.87 N +ATOM 6679 CA GLU C 547 1.268 -8.913 -81.504 1.00 88.05 C +ATOM 6680 C GLU C 547 1.741 -7.645 -82.202 1.00 90.60 C +ATOM 6681 O GLU C 547 1.067 -6.609 -82.155 1.00 79.58 O +ATOM 6682 CB GLU C 547 0.097 -9.545 -82.248 1.00 82.93 C +ATOM 6683 CG GLU C 547 -0.048 -11.022 -81.953 1.00 82.39 C +ATOM 6684 CD GLU C 547 -0.903 -11.724 -82.977 1.00 88.14 C +ATOM 6685 OE1 GLU C 547 -1.798 -11.064 -83.542 1.00 78.51 O +ATOM 6686 OE2 GLU C 547 -0.688 -12.933 -83.208 1.00102.17 O +ATOM 6687 N ASN C 548 2.934 -7.724 -82.784 1.00 93.06 N +ATOM 6688 CA ASN C 548 3.531 -6.618 -83.519 1.00 84.42 C +ATOM 6689 C ASN C 548 2.616 -6.164 -84.652 1.00 83.50 C +ATOM 6690 O ASN C 548 2.156 -6.981 -85.455 1.00 78.60 O +ATOM 6691 CB ASN C 548 4.883 -7.064 -84.077 1.00 81.74 C +ATOM 6692 CG ASN C 548 5.886 -5.940 -84.155 1.00 83.83 C +ATOM 6693 OD1 ASN C 548 5.532 -4.768 -84.028 1.00 90.41 O +ATOM 6694 ND2 ASN C 548 7.148 -6.290 -84.367 1.00 80.73 N +ATOM 6695 N ASP C 549 2.360 -4.856 -84.734 1.00 81.70 N +ATOM 6696 CA ASP C 549 1.599 -4.313 -85.853 1.00 76.46 C +ATOM 6697 C ASP C 549 2.456 -3.478 -86.785 1.00 82.51 C +ATOM 6698 O ASP C 549 2.415 -3.676 -88.001 1.00 86.47 O +ATOM 6699 CB ASP C 549 0.453 -3.427 -85.348 1.00 66.99 C +ATOM 6700 CG ASP C 549 -0.234 -4.002 -84.160 1.00 70.06 C +ATOM 6701 OD1 ASP C 549 -0.744 -5.131 -84.280 1.00 75.55 O +ATOM 6702 OD2 ASP C 549 -0.250 -3.330 -83.107 1.00 69.65 O +ATOM 6703 N LEU C 550 3.252 -2.561 -86.247 1.00 86.80 N +ATOM 6704 CA LEU C 550 4.132 -1.737 -87.066 1.00 88.40 C +ATOM 6705 C LEU C 550 5.424 -2.507 -87.300 1.00 92.85 C +ATOM 6706 O LEU C 550 6.199 -2.725 -86.362 1.00 91.13 O +ATOM 6707 CB LEU C 550 4.386 -0.381 -86.420 1.00 81.68 C +ATOM 6708 CG LEU C 550 3.462 0.711 -86.965 1.00 92.95 C +ATOM 6709 CD1 LEU C 550 3.865 2.059 -86.404 1.00 99.78 C +ATOM 6710 CD2 LEU C 550 3.450 0.740 -88.501 1.00 84.28 C +ATOM 6711 N ASP C 551 5.646 -2.922 -88.544 1.00 96.98 N +ATOM 6712 CA ASP C 551 6.861 -3.627 -88.939 1.00101.83 C +ATOM 6713 C ASP C 551 6.998 -4.930 -88.152 1.00100.79 C +ATOM 6714 O ASP C 551 6.000 -5.521 -87.728 1.00 93.79 O +ATOM 6715 CB ASP C 551 8.104 -2.745 -88.740 1.00107.19 C +ATOM 6716 CG ASP C 551 8.116 -1.528 -89.658 1.00114.35 C +ATOM 6717 OD1 ASP C 551 7.418 -1.553 -90.694 1.00113.07 O +ATOM 6718 OD2 ASP C 551 8.831 -0.548 -89.347 1.00115.10 O +TER 6719 ASP C 551 +ATOM 6720 N SER B 89 -67.368 -7.296-143.108 1.00 50.02 N +ATOM 6721 CA SER B 89 -66.539 -7.819-142.025 1.00 52.60 C +ATOM 6722 C SER B 89 -65.611 -6.727-141.483 1.00 51.61 C +ATOM 6723 O SER B 89 -65.478 -5.657-142.087 1.00 50.95 O +ATOM 6724 CB SER B 89 -65.732 -9.040-142.489 1.00 55.96 C +ATOM 6725 OG SER B 89 -66.573 -10.098-142.928 1.00 42.25 O +ATOM 6726 N SER B 90 -65.003 -7.005-140.326 1.00 48.73 N +ATOM 6727 CA SER B 90 -64.091 -6.091-139.640 1.00 50.70 C +ATOM 6728 C SER B 90 -64.775 -4.782-139.268 1.00 49.91 C +ATOM 6729 O SER B 90 -64.655 -3.777-139.981 1.00 41.58 O +ATOM 6730 CB SER B 90 -62.855 -5.797-140.493 1.00 52.91 C +ATOM 6731 OG SER B 90 -62.058 -4.799-139.879 1.00 53.36 O +ATOM 6732 N LYS B 91 -65.468 -4.781-138.126 1.00 50.69 N +ATOM 6733 CA LYS B 91 -66.105 -3.567-137.633 1.00 47.27 C +ATOM 6734 C LYS B 91 -65.085 -2.533-137.187 1.00 46.79 C +ATOM 6735 O LYS B 91 -65.414 -1.344-137.127 1.00 44.46 O +ATOM 6736 CB LYS B 91 -67.047 -3.899-136.474 1.00 41.98 C +ATOM 6737 CG LYS B 91 -68.211 -4.804-136.834 1.00 38.00 C +ATOM 6738 CD LYS B 91 -69.043 -5.097-135.598 1.00 38.00 C +ATOM 6739 CE LYS B 91 -69.992 -6.258-135.815 1.00 38.00 C +ATOM 6740 NZ LYS B 91 -71.357 -5.971-135.294 1.00 45.94 N +ATOM 6741 N LEU B 92 -63.857 -2.959-136.883 1.00 50.25 N +ATOM 6742 CA LEU B 92 -62.832 -2.022-136.438 1.00 50.67 C +ATOM 6743 C LEU B 92 -62.423 -1.089-137.572 1.00 52.75 C +ATOM 6744 O LEU B 92 -62.316 0.128-137.379 1.00 52.12 O +ATOM 6745 CB LEU B 92 -61.628 -2.790-135.886 1.00 43.67 C +ATOM 6746 CG LEU B 92 -60.665 -2.038-134.961 1.00 40.58 C +ATOM 6747 CD1 LEU B 92 -59.566 -1.349-135.745 1.00 61.03 C +ATOM 6748 CD2 LEU B 92 -61.416 -1.022-134.136 1.00 41.17 C +ATOM 6749 N GLN B 93 -62.199 -1.638-138.770 1.00 57.09 N +ATOM 6750 CA GLN B 93 -61.879 -0.789-139.913 1.00 58.57 C +ATOM 6751 C GLN B 93 -63.035 0.147-140.230 1.00 52.69 C +ATOM 6752 O GLN B 93 -62.822 1.305-140.607 1.00 50.41 O +ATOM 6753 CB GLN B 93 -61.540 -1.644-141.133 1.00 58.09 C +ATOM 6754 CG GLN B 93 -60.229 -2.391-141.022 1.00 61.13 C +ATOM 6755 CD GLN B 93 -59.875 -3.145-142.289 1.00 59.43 C +ATOM 6756 OE1 GLN B 93 -60.591 -3.086-143.291 1.00 51.42 O +ATOM 6757 NE2 GLN B 93 -58.759 -3.860-142.250 1.00 72.01 N +ATOM 6758 N ALA B 94 -64.268 -0.338-140.060 1.00 47.95 N +ATOM 6759 CA ALA B 94 -65.437 0.494-140.310 1.00 47.54 C +ATOM 6760 C ALA B 94 -65.502 1.679-139.355 1.00 50.01 C +ATOM 6761 O ALA B 94 -65.976 2.755-139.738 1.00 51.65 O +ATOM 6762 CB ALA B 94 -66.705 -0.353-140.201 1.00 46.14 C +ATOM 6763 N LEU B 95 -65.015 1.514-138.121 1.00 44.04 N +ATOM 6764 CA LEU B 95 -65.071 2.602-137.148 1.00 41.61 C +ATOM 6765 C LEU B 95 -64.201 3.775-137.581 1.00 45.59 C +ATOM 6766 O LEU B 95 -64.652 4.925-137.590 1.00 48.44 O +ATOM 6767 CB LEU B 95 -64.640 2.107-135.767 1.00 46.01 C +ATOM 6768 CG LEU B 95 -64.783 3.102-134.606 1.00 38.00 C +ATOM 6769 CD1 LEU B 95 -66.220 3.554-134.454 1.00 38.00 C +ATOM 6770 CD2 LEU B 95 -64.254 2.532-133.297 1.00 38.00 C +ATOM 6771 N PHE B 96 -62.937 3.511-137.914 1.00 45.08 N +ATOM 6772 CA PHE B 96 -62.018 4.590-138.248 1.00 42.80 C +ATOM 6773 C PHE B 96 -62.227 5.133-139.654 1.00 45.70 C +ATOM 6774 O PHE B 96 -61.749 6.233-139.953 1.00 45.40 O +ATOM 6775 CB PHE B 96 -60.578 4.116-138.061 1.00 40.00 C +ATOM 6776 CG PHE B 96 -60.228 3.820-136.627 1.00 42.39 C +ATOM 6777 CD1 PHE B 96 -59.955 4.848-135.738 1.00 38.00 C +ATOM 6778 CD2 PHE B 96 -60.218 2.516-136.159 1.00 39.51 C +ATOM 6779 CE1 PHE B 96 -59.649 4.573-134.424 1.00 38.00 C +ATOM 6780 CE2 PHE B 96 -59.919 2.239-134.849 1.00 38.00 C +ATOM 6781 CZ PHE B 96 -59.633 3.266-133.981 1.00 38.00 C +ATOM 6782 N ALA B 97 -62.943 4.407-140.511 1.00 49.06 N +ATOM 6783 CA ALA B 97 -63.297 4.904-141.832 1.00 48.93 C +ATOM 6784 C ALA B 97 -64.621 5.657-141.832 1.00 48.96 C +ATOM 6785 O ALA B 97 -65.067 6.114-142.890 1.00 46.34 O +ATOM 6786 CB ALA B 97 -63.357 3.741-142.828 1.00 49.14 C +ATOM 6787 N HIS B 98 -65.226 5.833-140.666 1.00 50.20 N +ATOM 6788 CA HIS B 98 -66.475 6.549-140.504 1.00 49.06 C +ATOM 6789 C HIS B 98 -66.215 8.054-140.529 1.00 48.70 C +ATOM 6790 O HIS B 98 -65.174 8.514-140.054 1.00 50.47 O +ATOM 6791 CB HIS B 98 -67.130 6.149-139.186 1.00 51.23 C +ATOM 6792 CG HIS B 98 -68.553 6.583-139.052 1.00 55.36 C +ATOM 6793 ND1 HIS B 98 -68.909 7.836-138.599 1.00 57.88 N +ATOM 6794 CD2 HIS B 98 -69.711 5.921-139.282 1.00 53.88 C +ATOM 6795 CE1 HIS B 98 -70.226 7.934-138.577 1.00 59.93 C +ATOM 6796 NE2 HIS B 98 -70.737 6.786-138.985 1.00 64.39 N +ATOM 6797 N PRO B 99 -67.151 8.837-141.070 1.00 48.78 N +ATOM 6798 CA PRO B 99 -66.953 10.297-141.138 1.00 48.69 C +ATOM 6799 C PRO B 99 -66.626 10.955-139.808 1.00 49.56 C +ATOM 6800 O PRO B 99 -66.000 12.022-139.799 1.00 45.72 O +ATOM 6801 CB PRO B 99 -68.294 10.799-141.690 1.00 52.89 C +ATOM 6802 CG PRO B 99 -68.805 9.663-142.502 1.00 60.83 C +ATOM 6803 CD PRO B 99 -68.353 8.406-141.804 1.00 55.62 C +ATOM 6804 N LEU B 100 -67.041 10.367-138.685 1.00 51.41 N +ATOM 6805 CA LEU B 100 -66.736 10.961-137.387 1.00 54.66 C +ATOM 6806 C LEU B 100 -65.239 10.957-137.114 1.00 57.13 C +ATOM 6807 O LEU B 100 -64.678 11.957-136.652 1.00 60.08 O +ATOM 6808 CB LEU B 100 -67.473 10.218-136.277 1.00 50.78 C +ATOM 6809 CG LEU B 100 -68.508 11.040-135.518 1.00 46.65 C +ATOM 6810 CD1 LEU B 100 -69.146 10.191-134.438 1.00 43.65 C +ATOM 6811 CD2 LEU B 100 -67.870 12.294-134.930 1.00 47.86 C +ATOM 6812 N TYR B 101 -64.581 9.831-137.375 1.00 52.44 N +ATOM 6813 CA TYR B 101 -63.154 9.692-137.115 1.00 51.79 C +ATOM 6814 C TYR B 101 -62.305 10.214-138.267 1.00 53.93 C +ATOM 6815 O TYR B 101 -61.232 9.668-138.543 1.00 52.86 O +ATOM 6816 CB TYR B 101 -62.817 8.232-136.856 1.00 47.67 C +ATOM 6817 CG TYR B 101 -63.471 7.663-135.628 1.00 44.69 C +ATOM 6818 CD1 TYR B 101 -64.816 7.342-135.621 1.00 41.91 C +ATOM 6819 CD2 TYR B 101 -62.737 7.433-134.478 1.00 49.14 C +ATOM 6820 CE1 TYR B 101 -65.414 6.815-134.505 1.00 42.58 C +ATOM 6821 CE2 TYR B 101 -63.326 6.903-133.357 1.00 47.02 C +ATOM 6822 CZ TYR B 101 -64.665 6.591-133.374 1.00 41.59 C +ATOM 6823 OH TYR B 101 -65.258 6.061-132.253 1.00 38.00 O +ATOM 6824 N ASN B 102 -62.768 11.268-138.940 1.00 54.44 N +ATOM 6825 CA ASN B 102 -62.074 11.787-140.112 1.00 49.81 C +ATOM 6826 C ASN B 102 -62.285 13.289-140.247 1.00 55.60 C +ATOM 6827 O ASN B 102 -61.530 13.966-140.954 1.00 60.45 O +ATOM 6828 CB ASN B 102 -62.539 11.052-141.371 1.00 48.82 C +ATOM 6829 CG ASN B 102 -61.880 9.687-141.532 1.00 51.99 C +ATOM 6830 OD1 ASN B 102 -60.666 9.555-141.376 1.00 54.28 O +ATOM 6831 ND2 ASN B 102 -62.679 8.666-141.823 1.00 50.71 N +ATOM 6832 N VAL B 103 -63.310 13.818-139.590 1.00 61.10 N +ATOM 6833 CA VAL B 103 -63.573 15.264-139.658 1.00 68.36 C +ATOM 6834 C VAL B 103 -62.422 16.019-138.997 1.00 63.47 C +ATOM 6835 O VAL B 103 -61.878 15.545-137.982 1.00 63.11 O +ATOM 6836 CB VAL B 103 -64.909 15.597-138.991 1.00 65.30 C +ATOM 6837 CG1 VAL B 103 -66.063 15.121-139.861 1.00 62.41 C +ATOM 6838 CG2 VAL B 103 -64.984 14.968-137.605 1.00 50.45 C +ATOM 6839 N PRO B 104 -62.015 17.177-139.519 1.00 61.80 N +ATOM 6840 CA PRO B 104 -60.951 17.942-138.858 1.00 69.62 C +ATOM 6841 C PRO B 104 -61.389 18.399-137.477 1.00 82.19 C +ATOM 6842 O PRO B 104 -62.566 18.676-137.234 1.00 89.52 O +ATOM 6843 CB PRO B 104 -60.732 19.138-139.794 1.00 59.85 C +ATOM 6844 CG PRO B 104 -61.266 18.699-141.106 1.00 64.00 C +ATOM 6845 CD PRO B 104 -62.414 17.786-140.796 1.00 62.13 C +ATOM 6846 N GLU B 105 -60.429 18.468-136.564 1.00 77.79 N +ATOM 6847 CA GLU B 105 -60.706 18.885-135.200 1.00 82.33 C +ATOM 6848 C GLU B 105 -60.488 20.386-135.062 1.00 86.51 C +ATOM 6849 O GLU B 105 -59.494 20.923-135.566 1.00 82.98 O +ATOM 6850 CB GLU B 105 -59.833 18.120-134.207 1.00 85.10 C +ATOM 6851 CG GLU B 105 -60.506 16.889-133.617 1.00 85.20 C +ATOM 6852 CD GLU B 105 -59.559 16.074-132.758 1.00 83.82 C +ATOM 6853 OE1 GLU B 105 -58.434 15.790-133.225 1.00 83.41 O +ATOM 6854 OE2 GLU B 105 -59.935 15.729-131.614 1.00 76.12 O +ATOM 6855 N GLU B 106 -61.436 21.064-134.392 1.00 92.97 N +ATOM 6856 CA GLU B 106 -61.404 22.504-134.173 1.00 96.02 C +ATOM 6857 C GLU B 106 -61.041 22.817-132.724 1.00 96.02 C +ATOM 6858 O GLU B 106 -61.469 22.103-131.809 1.00 95.14 O +ATOM 6859 CB GLU B 106 -62.760 23.147-134.500 1.00100.02 C +ATOM 6860 CG GLU B 106 -63.364 22.736-135.844 1.00103.48 C +ATOM 6861 CD GLU B 106 -62.654 23.357-137.041 1.00106.10 C +ATOM 6862 OE1 GLU B 106 -61.824 24.274-136.847 1.00100.77 O +ATOM 6863 OE2 GLU B 106 -62.922 22.918-138.180 1.00106.39 O +ATOM 6864 N PRO B 107 -60.251 23.876-132.478 1.00 93.41 N +ATOM 6865 CA PRO B 107 -59.624 24.723-133.504 1.00 91.70 C +ATOM 6866 C PRO B 107 -58.430 24.037-134.180 1.00 91.00 C +ATOM 6867 O PRO B 107 -57.831 23.150-133.573 1.00 94.15 O +ATOM 6868 CB PRO B 107 -59.162 25.956-132.710 1.00 84.76 C +ATOM 6869 CG PRO B 107 -59.910 25.891-131.403 1.00 85.19 C +ATOM 6870 CD PRO B 107 -60.065 24.432-131.129 1.00 88.95 C +ATOM 6871 N PRO B 108 -58.093 24.432-135.409 1.00 91.45 N +ATOM 6872 CA PRO B 108 -56.916 23.854-136.069 1.00 85.98 C +ATOM 6873 C PRO B 108 -55.627 24.332-135.416 1.00 89.28 C +ATOM 6874 O PRO B 108 -55.599 25.319-134.676 1.00 93.36 O +ATOM 6875 CB PRO B 108 -57.020 24.355-137.515 1.00 87.34 C +ATOM 6876 CG PRO B 108 -58.383 24.973-137.650 1.00 85.00 C +ATOM 6877 CD PRO B 108 -58.814 25.377-136.277 1.00 88.52 C +ATOM 6878 N LEU B 109 -54.539 23.626-135.720 1.00 86.93 N +ATOM 6879 CA LEU B 109 -53.250 23.869-135.081 1.00 92.12 C +ATOM 6880 C LEU B 109 -52.377 24.737-135.979 1.00 87.90 C +ATOM 6881 O LEU B 109 -52.088 24.367-137.122 1.00 83.85 O +ATOM 6882 CB LEU B 109 -52.545 22.554-134.744 1.00 91.82 C +ATOM 6883 CG LEU B 109 -53.371 21.474-134.035 1.00 89.29 C +ATOM 6884 CD1 LEU B 109 -52.595 20.174-133.985 1.00 79.10 C +ATOM 6885 CD2 LEU B 109 -53.776 21.906-132.626 1.00 76.01 C +ATOM 6886 N LEU B 110 -51.956 25.888-135.451 1.00 94.63 N +ATOM 6887 CA LEU B 110 -51.049 26.773-136.171 1.00 92.32 C +ATOM 6888 C LEU B 110 -49.619 26.241-136.197 1.00 90.74 C +ATOM 6889 O LEU B 110 -48.841 26.635-137.072 1.00 85.57 O +ATOM 6890 CB LEU B 110 -51.090 28.177-135.557 1.00 86.50 C +ATOM 6891 CG LEU B 110 -51.516 28.308-134.087 1.00 90.73 C +ATOM 6892 CD1 LEU B 110 -50.777 29.449-133.404 1.00 84.88 C +ATOM 6893 CD2 LEU B 110 -53.029 28.503-133.946 1.00 82.08 C +ATOM 6894 N GLY B 111 -49.257 25.365-135.266 1.00 94.53 N +ATOM 6895 CA GLY B 111 -47.906 24.853-135.158 1.00 92.94 C +ATOM 6896 C GLY B 111 -47.076 25.638-134.155 1.00 93.04 C +ATOM 6897 O GLY B 111 -47.495 26.660-133.605 1.00 94.63 O +ATOM 6898 N ALA B 112 -45.862 25.133-133.924 1.00 84.92 N +ATOM 6899 CA ALA B 112 -44.913 25.740-132.996 1.00 87.33 C +ATOM 6900 C ALA B 112 -45.473 25.819-131.576 1.00 88.95 C +ATOM 6901 O ALA B 112 -44.999 25.113-130.681 1.00 85.43 O +ATOM 6902 CB ALA B 112 -44.491 27.129-133.489 1.00 80.25 C +ATOM 6903 N GLU B 113 -46.481 26.667-131.355 1.00 95.79 N +ATOM 6904 CA GLU B 113 -47.074 26.842-130.032 1.00 94.67 C +ATOM 6905 C GLU B 113 -48.129 25.789-129.708 1.00 88.61 C +ATOM 6906 O GLU B 113 -48.628 25.758-128.575 1.00 80.75 O +ATOM 6907 CB GLU B 113 -47.701 28.239-129.911 1.00 98.13 C +ATOM 6908 CG GLU B 113 -46.766 29.385-130.282 1.00 96.82 C +ATOM 6909 CD GLU B 113 -46.721 29.641-131.783 1.00110.59 C +ATOM 6910 OE1 GLU B 113 -47.694 29.284-132.485 1.00107.82 O +ATOM 6911 OE2 GLU B 113 -45.707 30.190-132.263 1.00114.57 O +ATOM 6912 N ASP B 114 -48.468 24.923-130.658 1.00 87.17 N +ATOM 6913 CA ASP B 114 -49.432 23.853-130.445 1.00 80.80 C +ATOM 6914 C ASP B 114 -48.765 22.487-130.380 1.00 77.41 C +ATOM 6915 O ASP B 114 -49.460 21.467-130.340 1.00 71.54 O +ATOM 6916 CB ASP B 114 -50.497 23.878-131.544 1.00 87.00 C +ATOM 6917 CG ASP B 114 -51.420 25.087-131.440 1.00 89.38 C +ATOM 6918 OD1 ASP B 114 -51.295 25.855-130.461 1.00 91.30 O +ATOM 6919 OD2 ASP B 114 -52.274 25.270-132.339 1.00 87.89 O +ATOM 6920 N SER B 115 -47.432 22.448-130.354 1.00 81.25 N +ATOM 6921 CA SER B 115 -46.649 21.232-130.147 1.00 82.49 C +ATOM 6922 C SER B 115 -45.857 21.425-128.858 1.00 72.26 C +ATOM 6923 O SER B 115 -44.969 22.282-128.799 1.00 72.27 O +ATOM 6924 CB SER B 115 -45.721 20.965-131.335 1.00 68.22 C +ATOM 6925 OG SER B 115 -46.406 20.327-132.398 1.00 54.53 O +ATOM 6926 N LEU B 116 -46.180 20.640-127.823 1.00 64.29 N +ATOM 6927 CA LEU B 116 -45.621 20.902-126.497 1.00 67.77 C +ATOM 6928 C LEU B 116 -44.108 20.782-126.470 1.00 62.87 C +ATOM 6929 O LEU B 116 -43.467 21.353-125.580 1.00 65.78 O +ATOM 6930 CB LEU B 116 -46.237 19.969-125.444 1.00 72.06 C +ATOM 6931 CG LEU B 116 -46.168 18.434-125.493 1.00 61.27 C +ATOM 6932 CD1 LEU B 116 -44.802 17.872-125.123 1.00 56.12 C +ATOM 6933 CD2 LEU B 116 -47.215 17.871-124.562 1.00 55.95 C +ATOM 6934 N LEU B 117 -43.527 20.042-127.403 1.00 55.31 N +ATOM 6935 CA LEU B 117 -42.087 19.861-127.473 1.00 53.92 C +ATOM 6936 C LEU B 117 -41.554 20.684-128.635 1.00 54.44 C +ATOM 6937 O LEU B 117 -42.012 20.527-129.773 1.00 60.70 O +ATOM 6938 CB LEU B 117 -41.735 18.385-127.637 1.00 53.54 C +ATOM 6939 CG LEU B 117 -40.714 17.839-126.643 1.00 42.68 C +ATOM 6940 CD1 LEU B 117 -41.214 18.001-125.224 1.00 42.35 C +ATOM 6941 CD2 LEU B 117 -40.428 16.386-126.951 1.00 39.38 C +ATOM 6942 N ALA B 118 -40.606 21.569-128.347 1.00 49.42 N +ATOM 6943 CA ALA B 118 -39.923 22.302-129.401 1.00 54.02 C +ATOM 6944 C ALA B 118 -38.862 21.400-130.017 1.00 58.45 C +ATOM 6945 O ALA B 118 -38.072 20.781-129.299 1.00 62.71 O +ATOM 6946 CB ALA B 118 -39.296 23.583-128.853 1.00 57.52 C +ATOM 6947 N SER B 119 -38.851 21.324-131.349 1.00 60.31 N +ATOM 6948 CA SER B 119 -38.017 20.346-132.040 1.00 57.80 C +ATOM 6949 C SER B 119 -36.538 20.543-131.719 1.00 60.35 C +ATOM 6950 O SER B 119 -35.863 19.619-131.252 1.00 57.22 O +ATOM 6951 CB SER B 119 -38.270 20.430-133.546 1.00 64.16 C +ATOM 6952 OG SER B 119 -38.263 21.778-133.980 1.00 74.26 O +ATOM 6953 N GLN B 120 -36.013 21.747-131.955 1.00 63.07 N +ATOM 6954 CA GLN B 120 -34.579 21.954-131.781 1.00 65.71 C +ATOM 6955 C GLN B 120 -34.172 21.782-130.324 1.00 63.39 C +ATOM 6956 O GLN B 120 -33.108 21.225-130.032 1.00 69.07 O +ATOM 6957 CB GLN B 120 -34.171 23.334-132.299 1.00 75.56 C +ATOM 6958 CG GLN B 120 -32.666 23.491-132.515 1.00 87.11 C +ATOM 6959 CD GLN B 120 -32.238 24.933-132.756 1.00104.31 C +ATOM 6960 OE1 GLN B 120 -32.246 25.761-131.841 1.00105.19 O +ATOM 6961 NE2 GLN B 120 -31.872 25.239-133.997 1.00 98.80 N +ATOM 6962 N GLU B 121 -35.018 22.226-129.393 1.00 58.04 N +ATOM 6963 CA GLU B 121 -34.677 22.101-127.981 1.00 62.48 C +ATOM 6964 C GLU B 121 -34.734 20.648-127.521 1.00 57.36 C +ATOM 6965 O GLU B 121 -33.858 20.191-126.778 1.00 57.44 O +ATOM 6966 CB GLU B 121 -35.614 22.964-127.138 1.00 70.65 C +ATOM 6967 CG GLU B 121 -35.396 22.811-125.645 1.00 74.38 C +ATOM 6968 CD GLU B 121 -36.556 23.339-124.824 1.00 79.65 C +ATOM 6969 OE1 GLU B 121 -37.550 23.813-125.419 1.00 75.02 O +ATOM 6970 OE2 GLU B 121 -36.481 23.258-123.580 1.00 85.39 O +ATOM 6971 N ALA B 122 -35.757 19.909-127.951 1.00 54.15 N +ATOM 6972 CA ALA B 122 -35.899 18.523-127.523 1.00 47.94 C +ATOM 6973 C ALA B 122 -34.771 17.659-128.062 1.00 48.75 C +ATOM 6974 O ALA B 122 -34.247 16.799-127.346 1.00 47.81 O +ATOM 6975 CB ALA B 122 -37.249 17.968-127.968 1.00 51.50 C +ATOM 6976 N LEU B 123 -34.403 17.852-129.332 1.00 49.61 N +ATOM 6977 CA LEU B 123 -33.332 17.051-129.913 1.00 52.32 C +ATOM 6978 C LEU B 123 -32.004 17.278-129.198 1.00 59.64 C +ATOM 6979 O LEU B 123 -31.217 16.337-129.042 1.00 61.85 O +ATOM 6980 CB LEU B 123 -33.189 17.351-131.406 1.00 47.65 C +ATOM 6981 CG LEU B 123 -33.991 16.489-132.394 1.00 49.79 C +ATOM 6982 CD1 LEU B 123 -33.791 15.002-132.121 1.00 52.34 C +ATOM 6983 CD2 LEU B 123 -35.468 16.831-132.420 1.00 55.27 C +ATOM 6984 N ARG B 124 -31.742 18.504-128.741 1.00 56.50 N +ATOM 6985 CA ARG B 124 -30.498 18.768-128.023 1.00 52.59 C +ATOM 6986 C ARG B 124 -30.488 18.085-126.661 1.00 53.66 C +ATOM 6987 O ARG B 124 -29.497 17.449-126.286 1.00 56.62 O +ATOM 6988 CB ARG B 124 -30.286 20.270-127.865 1.00 59.58 C +ATOM 6989 CG ARG B 124 -28.913 20.634-127.329 1.00 70.30 C +ATOM 6990 CD ARG B 124 -28.816 22.120-127.017 1.00 87.19 C +ATOM 6991 NE ARG B 124 -29.350 22.942-128.100 1.00 92.17 N +ATOM 6992 CZ ARG B 124 -30.465 23.664-128.018 1.00 93.02 C +ATOM 6993 NH1 ARG B 124 -31.174 23.681-126.894 1.00 82.29 N +ATOM 6994 NH2 ARG B 124 -30.867 24.376-129.064 1.00 91.23 N +ATOM 6995 N TYR B 125 -31.580 18.213-125.902 1.00 53.91 N +ATOM 6996 CA TYR B 125 -31.637 17.609-124.573 1.00 53.32 C +ATOM 6997 C TYR B 125 -31.530 16.095-124.657 1.00 54.68 C +ATOM 6998 O TYR B 125 -30.778 15.469-123.901 1.00 57.53 O +ATOM 6999 CB TYR B 125 -32.931 18.009-123.865 1.00 47.96 C +ATOM 7000 CG TYR B 125 -33.084 17.435-122.472 1.00 50.11 C +ATOM 7001 CD1 TYR B 125 -32.121 17.658-121.493 1.00 64.05 C +ATOM 7002 CD2 TYR B 125 -34.193 16.668-122.135 1.00 50.72 C +ATOM 7003 CE1 TYR B 125 -32.263 17.138-120.213 1.00 65.78 C +ATOM 7004 CE2 TYR B 125 -34.344 16.145-120.860 1.00 59.02 C +ATOM 7005 CZ TYR B 125 -33.375 16.383-119.904 1.00 66.73 C +ATOM 7006 OH TYR B 125 -33.522 15.866-118.636 1.00 66.75 O +ATOM 7007 N TYR B 126 -32.283 15.484-125.573 1.00 51.84 N +ATOM 7008 CA TYR B 126 -32.213 14.038-125.726 1.00 47.56 C +ATOM 7009 C TYR B 126 -30.834 13.588-126.195 1.00 53.14 C +ATOM 7010 O TYR B 126 -30.413 12.467-125.888 1.00 54.53 O +ATOM 7011 CB TYR B 126 -33.299 13.565-126.686 1.00 42.55 C +ATOM 7012 CG TYR B 126 -34.691 13.610-126.101 1.00 40.13 C +ATOM 7013 CD1 TYR B 126 -34.904 13.424-124.741 1.00 44.42 C +ATOM 7014 CD2 TYR B 126 -35.794 13.828-126.909 1.00 45.56 C +ATOM 7015 CE1 TYR B 126 -36.185 13.458-124.205 1.00 46.63 C +ATOM 7016 CE2 TYR B 126 -37.075 13.862-126.385 1.00 43.26 C +ATOM 7017 CZ TYR B 126 -37.265 13.678-125.036 1.00 44.57 C +ATOM 7018 OH TYR B 126 -38.545 13.717-124.532 1.00 44.54 O +ATOM 7019 N ARG B 127 -30.118 14.437-126.937 1.00 55.59 N +ATOM 7020 CA ARG B 127 -28.767 14.085-127.367 1.00 58.05 C +ATOM 7021 C ARG B 127 -27.773 14.110-126.208 1.00 58.76 C +ATOM 7022 O ARG B 127 -26.827 13.312-126.186 1.00 54.38 O +ATOM 7023 CB ARG B 127 -28.314 15.037-128.474 1.00 60.17 C +ATOM 7024 CG ARG B 127 -27.092 14.585-129.252 1.00 58.48 C +ATOM 7025 CD ARG B 127 -26.852 15.496-130.449 1.00 64.39 C +ATOM 7026 NE ARG B 127 -27.924 15.410-131.443 1.00 76.41 N +ATOM 7027 CZ ARG B 127 -28.871 16.330-131.622 1.00 66.13 C +ATOM 7028 NH1 ARG B 127 -28.889 17.428-130.875 1.00 63.01 N +ATOM 7029 NH2 ARG B 127 -29.798 16.154-132.558 1.00 51.57 N +ATOM 7030 N ARG B 128 -27.972 15.005-125.235 1.00 54.48 N +ATOM 7031 CA ARG B 128 -27.079 15.050-124.082 1.00 50.97 C +ATOM 7032 C ARG B 128 -27.281 13.844-123.185 1.00 55.67 C +ATOM 7033 O ARG B 128 -26.307 13.248-122.713 1.00 62.56 O +ATOM 7034 CB ARG B 128 -27.297 16.335-123.288 1.00 56.70 C +ATOM 7035 CG ARG B 128 -26.660 17.557-123.914 1.00 73.40 C +ATOM 7036 CD ARG B 128 -26.491 18.686-122.903 1.00 86.76 C +ATOM 7037 NE ARG B 128 -27.762 19.316-122.552 1.00 94.33 N +ATOM 7038 CZ ARG B 128 -28.216 20.440-123.105 1.00 95.69 C +ATOM 7039 NH1 ARG B 128 -27.505 21.062-124.041 1.00 85.73 N +ATOM 7040 NH2 ARG B 128 -29.385 20.943-122.723 1.00 91.33 N +ATOM 7041 N LYS B 129 -28.539 13.467-122.943 1.00 53.59 N +ATOM 7042 CA LYS B 129 -28.811 12.302-122.109 1.00 59.57 C +ATOM 7043 C LYS B 129 -28.252 11.026-122.733 1.00 63.80 C +ATOM 7044 O LYS B 129 -27.906 10.083-122.011 1.00 59.62 O +ATOM 7045 CB LYS B 129 -30.317 12.170-121.861 1.00 51.56 C +ATOM 7046 CG LYS B 129 -30.904 13.189-120.885 1.00 46.25 C +ATOM 7047 CD LYS B 129 -31.487 12.510-119.642 1.00 61.55 C +ATOM 7048 CE LYS B 129 -30.404 11.854-118.785 1.00 63.44 C +ATOM 7049 NZ LYS B 129 -30.942 11.131-117.591 1.00 54.79 N +ATOM 7050 N VAL B 130 -28.161 10.977-124.065 1.00 67.85 N +ATOM 7051 CA VAL B 130 -27.505 9.857-124.736 1.00 66.93 C +ATOM 7052 C VAL B 130 -25.994 9.932-124.554 1.00 69.66 C +ATOM 7053 O VAL B 130 -25.320 8.907-124.389 1.00 72.56 O +ATOM 7054 CB VAL B 130 -27.896 9.819-126.222 1.00 56.74 C +ATOM 7055 CG1 VAL B 130 -27.023 8.830-126.977 1.00 58.37 C +ATOM 7056 CG2 VAL B 130 -29.361 9.446-126.366 1.00 52.14 C +ATOM 7057 N ALA B 131 -25.433 11.141-124.602 1.00 65.84 N +ATOM 7058 CA ALA B 131 -24.006 11.292-124.347 1.00 67.85 C +ATOM 7059 C ALA B 131 -23.669 10.893-122.916 1.00 75.50 C +ATOM 7060 O ALA B 131 -22.731 10.123-122.678 1.00 77.61 O +ATOM 7061 CB ALA B 131 -23.574 12.731-124.626 1.00 63.85 C +ATOM 7062 N ARG B 132 -24.458 11.372-121.949 1.00 74.50 N +ATOM 7063 CA ARG B 132 -24.194 11.043-120.553 1.00 78.50 C +ATOM 7064 C ARG B 132 -24.392 9.558-120.280 1.00 75.54 C +ATOM 7065 O ARG B 132 -23.670 8.982-119.458 1.00 77.56 O +ATOM 7066 CB ARG B 132 -25.089 11.878-119.632 1.00 80.01 C +ATOM 7067 CG ARG B 132 -24.805 13.369-119.668 1.00 81.56 C +ATOM 7068 CD ARG B 132 -25.634 14.127-118.637 1.00 99.05 C +ATOM 7069 NE ARG B 132 -25.397 15.567-118.711 1.00119.62 N +ATOM 7070 CZ ARG B 132 -26.012 16.472-117.955 1.00119.43 C +ATOM 7071 NH1 ARG B 132 -26.910 16.089-117.054 1.00118.44 N +ATOM 7072 NH2 ARG B 132 -25.729 17.761-118.099 1.00108.11 N +ATOM 7073 N TRP B 133 -25.353 8.923-120.957 1.00 70.56 N +ATOM 7074 CA TRP B 133 -25.573 7.494-120.758 1.00 77.16 C +ATOM 7075 C TRP B 133 -24.387 6.680-121.266 1.00 76.26 C +ATOM 7076 O TRP B 133 -24.020 5.665-120.661 1.00 81.12 O +ATOM 7077 CB TRP B 133 -26.874 7.049-121.432 1.00 70.73 C +ATOM 7078 CG TRP B 133 -27.290 5.639-121.068 1.00 66.73 C +ATOM 7079 CD1 TRP B 133 -28.121 5.265-120.050 1.00 71.34 C +ATOM 7080 CD2 TRP B 133 -26.903 4.430-121.731 1.00 64.34 C +ATOM 7081 NE1 TRP B 133 -28.261 3.898-120.029 1.00 72.15 N +ATOM 7082 CE2 TRP B 133 -27.526 3.362-121.054 1.00 68.20 C +ATOM 7083 CE3 TRP B 133 -26.087 4.147-122.829 1.00 63.28 C +ATOM 7084 CZ2 TRP B 133 -27.361 2.036-121.441 1.00 66.86 C +ATOM 7085 CZ3 TRP B 133 -25.925 2.830-123.212 1.00 66.47 C +ATOM 7086 CH2 TRP B 133 -26.559 1.790-122.520 1.00 68.04 C +ATOM 7087 N ASN B 134 -23.816 7.067-122.408 1.00 69.69 N +ATOM 7088 CA ASN B 134 -22.698 6.310-122.961 1.00 77.46 C +ATOM 7089 C ASN B 134 -21.467 6.379-122.061 1.00 83.80 C +ATOM 7090 O ASN B 134 -20.728 5.395-121.929 1.00 80.86 O +ATOM 7091 CB ASN B 134 -22.378 6.817-124.364 1.00 79.82 C +ATOM 7092 CG ASN B 134 -23.357 6.304-125.392 1.00 80.79 C +ATOM 7093 OD1 ASN B 134 -23.776 5.145-125.332 1.00 78.14 O +ATOM 7094 ND2 ASN B 134 -23.741 7.161-126.335 1.00 76.54 N +ATOM 7095 N ARG B 135 -21.242 7.524-121.414 1.00 83.85 N +ATOM 7096 CA ARG B 135 -20.129 7.639-120.474 1.00 84.10 C +ATOM 7097 C ARG B 135 -20.374 6.806-119.220 1.00 83.47 C +ATOM 7098 O ARG B 135 -19.565 5.939-118.866 1.00 79.97 O +ATOM 7099 CB ARG B 135 -19.912 9.099-120.096 1.00 82.91 C +ATOM 7100 CG ARG B 135 -18.845 9.819-120.882 1.00 79.58 C +ATOM 7101 CD ARG B 135 -18.614 11.189-120.271 1.00 89.59 C +ATOM 7102 NE ARG B 135 -18.234 11.096-118.857 1.00114.39 N +ATOM 7103 CZ ARG B 135 -18.999 11.441-117.822 1.00118.46 C +ATOM 7104 NH1 ARG B 135 -20.218 11.923-118.017 1.00118.14 N +ATOM 7105 NH2 ARG B 135 -18.535 11.307-116.585 1.00 99.33 N +ATOM 7106 N ARG B 136 -21.509 7.043-118.548 1.00 79.92 N +ATOM 7107 CA ARG B 136 -21.775 6.446-117.240 1.00 83.16 C +ATOM 7108 C ARG B 136 -21.937 4.930-117.319 1.00 88.97 C +ATOM 7109 O ARG B 136 -21.683 4.229-116.333 1.00 84.46 O +ATOM 7110 CB ARG B 136 -23.036 7.090-116.651 1.00 81.96 C +ATOM 7111 CG ARG B 136 -22.825 8.522-116.191 1.00 84.22 C +ATOM 7112 CD ARG B 136 -23.947 9.039-115.311 1.00 78.43 C +ATOM 7113 NE ARG B 136 -23.758 10.461-115.032 1.00 87.09 N +ATOM 7114 CZ ARG B 136 -24.694 11.258-114.530 1.00 97.70 C +ATOM 7115 NH1 ARG B 136 -25.896 10.773-114.254 1.00 92.14 N +ATOM 7116 NH2 ARG B 136 -24.432 12.541-114.311 1.00108.31 N +ATOM 7117 N HIS B 137 -22.383 4.414-118.472 1.00 91.02 N +ATOM 7118 CA HIS B 137 -22.508 2.972-118.672 1.00 85.65 C +ATOM 7119 C HIS B 137 -21.159 2.345-118.998 1.00 87.46 C +ATOM 7120 O HIS B 137 -20.876 1.218-118.573 1.00 97.45 O +ATOM 7121 CB HIS B 137 -23.512 2.673-119.788 1.00 78.27 C +ATOM 7122 CG HIS B 137 -23.494 1.251-120.265 1.00 86.64 C +ATOM 7123 ND1 HIS B 137 -24.099 0.225-119.571 1.00 93.92 N +ATOM 7124 CD2 HIS B 137 -22.947 0.687-121.370 1.00 82.20 C +ATOM 7125 CE1 HIS B 137 -23.925 -0.909-120.227 1.00 87.03 C +ATOM 7126 NE2 HIS B 137 -23.230 -0.656-121.322 1.00 83.07 N +ATOM 7127 N LYS B 138 -20.316 3.065-119.748 1.00 75.65 N +ATOM 7128 CA LYS B 138 -18.968 2.583-120.031 1.00 75.90 C +ATOM 7129 C LYS B 138 -18.169 2.374-118.750 1.00 83.15 C +ATOM 7130 O LYS B 138 -17.470 1.363-118.600 1.00 83.99 O +ATOM 7131 CB LYS B 138 -18.251 3.563-120.957 1.00 64.37 C +ATOM 7132 CG LYS B 138 -16.755 3.320-121.035 1.00 65.69 C +ATOM 7133 CD LYS B 138 -16.075 4.244-122.023 1.00 66.08 C +ATOM 7134 CE LYS B 138 -16.496 3.918-123.455 1.00 72.45 C +ATOM 7135 NZ LYS B 138 -16.191 2.516-123.887 1.00 83.49 N +ATOM 7136 N MET B 139 -18.282 3.306-117.803 1.00 86.47 N +ATOM 7137 CA MET B 139 -17.603 3.142-116.524 1.00 86.82 C +ATOM 7138 C MET B 139 -18.141 1.933-115.771 1.00 90.25 C +ATOM 7139 O MET B 139 -17.372 1.180-115.164 1.00 91.42 O +ATOM 7140 CB MET B 139 -17.761 4.411-115.687 1.00 89.06 C +ATOM 7141 CG MET B 139 -17.088 5.637-116.277 1.00 85.26 C +ATOM 7142 SD MET B 139 -16.982 6.987-115.089 1.00 90.80 S +ATOM 7143 CE MET B 139 -15.563 6.482-114.122 1.00 77.16 C +ATOM 7144 N TYR B 140 -19.455 1.721-115.808 1.00 86.08 N +ATOM 7145 CA TYR B 140 -20.043 0.551-115.173 1.00 85.55 C +ATOM 7146 C TYR B 140 -19.667 -0.711-115.949 1.00 89.33 C +ATOM 7147 O TYR B 140 -19.220 -1.701-115.367 1.00 95.26 O +ATOM 7148 CB TYR B 140 -21.566 0.680-115.071 1.00 75.68 C +ATOM 7149 CG TYR B 140 -22.190 -0.446-114.273 1.00 84.22 C +ATOM 7150 CD1 TYR B 140 -22.201 -0.415-112.882 1.00 91.90 C +ATOM 7151 CD2 TYR B 140 -22.746 -1.553-114.907 1.00 85.53 C +ATOM 7152 CE1 TYR B 140 -22.758 -1.451-112.142 1.00 92.84 C +ATOM 7153 CE2 TYR B 140 -23.308 -2.595-114.176 1.00 87.42 C +ATOM 7154 CZ TYR B 140 -23.311 -2.539-112.794 1.00 93.23 C +ATOM 7155 OH TYR B 140 -23.869 -3.568-112.061 1.00 86.53 O +ATOM 7156 N PRO B 151 -20.567 -0.761-130.353 1.00 81.15 N +ATOM 7157 CA PRO B 151 -20.477 0.698-130.487 1.00 83.09 C +ATOM 7158 C PRO B 151 -21.346 1.435-129.467 1.00 80.05 C +ATOM 7159 O PRO B 151 -22.204 0.805-128.846 1.00 73.04 O +ATOM 7160 CB PRO B 151 -20.979 0.945-131.914 1.00 79.33 C +ATOM 7161 CG PRO B 151 -21.878 -0.209-132.206 1.00 68.68 C +ATOM 7162 CD PRO B 151 -21.300 -1.385-131.470 1.00 58.85 C +ATOM 7163 N PRO B 152 -21.116 2.734-129.277 1.00 84.82 N +ATOM 7164 CA PRO B 152 -21.959 3.501-128.353 1.00 83.99 C +ATOM 7165 C PRO B 152 -23.326 3.775-128.961 1.00 79.30 C +ATOM 7166 O PRO B 152 -23.561 3.593-130.158 1.00 74.68 O +ATOM 7167 CB PRO B 152 -21.172 4.797-128.133 1.00 85.90 C +ATOM 7168 CG PRO B 152 -20.340 4.937-129.363 1.00 81.80 C +ATOM 7169 CD PRO B 152 -19.985 3.536-129.782 1.00 79.90 C +ATOM 7170 N LEU B 153 -24.232 4.238-128.104 1.00 78.64 N +ATOM 7171 CA LEU B 153 -25.597 4.527-128.521 1.00 65.25 C +ATOM 7172 C LEU B 153 -25.633 5.677-129.520 1.00 66.68 C +ATOM 7173 O LEU B 153 -24.837 6.618-129.453 1.00 64.65 O +ATOM 7174 CB LEU B 153 -26.463 4.864-127.310 1.00 60.68 C +ATOM 7175 CG LEU B 153 -27.716 4.008-127.147 1.00 63.48 C +ATOM 7176 CD1 LEU B 153 -28.583 4.104-128.393 1.00 68.17 C +ATOM 7177 CD2 LEU B 153 -27.344 2.561-126.858 1.00 62.81 C +ATOM 7178 N GLN B 154 -26.574 5.588-130.456 1.00 67.25 N +ATOM 7179 CA GLN B 154 -26.819 6.619-131.455 1.00 70.25 C +ATOM 7180 C GLN B 154 -28.257 7.097-131.320 1.00 60.62 C +ATOM 7181 O GLN B 154 -29.188 6.285-131.348 1.00 63.80 O +ATOM 7182 CB GLN B 154 -26.568 6.082-132.869 1.00 78.21 C +ATOM 7183 CG GLN B 154 -26.453 7.141-133.957 1.00 73.94 C +ATOM 7184 CD GLN B 154 -25.053 7.707-134.067 1.00 81.33 C +ATOM 7185 OE1 GLN B 154 -24.202 7.462-133.210 1.00 79.67 O +ATOM 7186 NE2 GLN B 154 -24.798 8.450-135.139 1.00 84.09 N +ATOM 7187 N LEU B 155 -28.439 8.404-131.168 1.00 48.05 N +ATOM 7188 CA LEU B 155 -29.770 8.987-131.050 1.00 47.49 C +ATOM 7189 C LEU B 155 -30.248 9.384-132.443 1.00 59.83 C +ATOM 7190 O LEU B 155 -29.812 10.404-132.987 1.00 67.87 O +ATOM 7191 CB LEU B 155 -29.747 10.182-130.102 1.00 44.97 C +ATOM 7192 CG LEU B 155 -31.084 10.812-129.709 1.00 44.74 C +ATOM 7193 CD1 LEU B 155 -31.447 11.951-130.652 1.00 48.31 C +ATOM 7194 CD2 LEU B 155 -32.190 9.760-129.652 1.00 38.00 C +ATOM 7195 N ARG B 156 -31.161 8.601-133.010 1.00 56.35 N +ATOM 7196 CA ARG B 156 -31.666 8.857-134.350 1.00 57.05 C +ATOM 7197 C ARG B 156 -33.044 9.498-134.284 1.00 52.88 C +ATOM 7198 O ARG B 156 -33.910 9.068-133.515 1.00 48.28 O +ATOM 7199 CB ARG B 156 -31.725 7.571-135.182 1.00 64.12 C +ATOM 7200 CG ARG B 156 -30.381 7.129-135.756 1.00 76.76 C +ATOM 7201 CD ARG B 156 -30.549 6.047-136.819 1.00 83.71 C +ATOM 7202 NE ARG B 156 -30.981 4.771-136.247 1.00 96.10 N +ATOM 7203 CZ ARG B 156 -30.159 3.805-135.844 1.00100.45 C +ATOM 7204 NH1 ARG B 156 -28.843 3.954-135.944 1.00 91.20 N +ATOM 7205 NH2 ARG B 156 -30.655 2.683-135.337 1.00105.91 N +ATOM 7206 N LEU B 157 -33.237 10.535-135.102 1.00 53.25 N +ATOM 7207 CA LEU B 157 -34.532 11.197-135.183 1.00 44.21 C +ATOM 7208 C LEU B 157 -35.619 10.230-135.621 1.00 41.82 C +ATOM 7209 O LEU B 157 -36.783 10.385-135.241 1.00 44.72 O +ATOM 7210 CB LEU B 157 -34.449 12.362-136.163 1.00 45.26 C +ATOM 7211 CG LEU B 157 -35.036 13.708-135.758 1.00 46.90 C +ATOM 7212 CD1 LEU B 157 -35.035 14.628-136.964 1.00 45.32 C +ATOM 7213 CD2 LEU B 157 -36.438 13.551-135.201 1.00 54.88 C +ATOM 7214 N GLU B 158 -35.253 9.212-136.392 1.00 41.44 N +ATOM 7215 CA GLU B 158 -36.210 8.241-136.893 1.00 42.43 C +ATOM 7216 C GLU B 158 -36.712 7.285-135.815 1.00 40.26 C +ATOM 7217 O GLU B 158 -37.480 6.377-136.144 1.00 38.00 O +ATOM 7218 CB GLU B 158 -35.582 7.440-138.037 1.00 52.93 C +ATOM 7219 CG GLU B 158 -34.817 8.280-139.056 1.00 53.14 C +ATOM 7220 CD GLU B 158 -33.342 8.437-138.698 1.00 68.15 C +ATOM 7221 OE1 GLU B 158 -32.974 9.497-138.148 1.00 68.76 O +ATOM 7222 OE2 GLU B 158 -32.559 7.488-138.929 1.00 69.13 O +ATOM 7223 N ALA B 159 -36.298 7.447-134.558 1.00 39.81 N +ATOM 7224 CA ALA B 159 -36.744 6.554-133.496 1.00 38.00 C +ATOM 7225 C ALA B 159 -38.210 6.798-133.156 1.00 38.00 C +ATOM 7226 O ALA B 159 -38.735 7.903-133.317 1.00 39.79 O +ATOM 7227 CB ALA B 159 -35.880 6.731-132.251 1.00 38.00 C +ATOM 7228 N SER B 160 -38.873 5.747-132.668 1.00 38.00 N +ATOM 7229 CA SER B 160 -40.311 5.833-132.434 1.00 38.00 C +ATOM 7230 C SER B 160 -40.643 6.829-131.331 1.00 38.30 C +ATOM 7231 O SER B 160 -41.454 7.739-131.531 1.00 39.96 O +ATOM 7232 CB SER B 160 -40.873 4.455-132.098 1.00 38.00 C +ATOM 7233 OG SER B 160 -40.568 3.535-133.126 1.00 42.04 O +ATOM 7234 N TRP B 161 -40.027 6.677-130.158 1.00 38.00 N +ATOM 7235 CA TRP B 161 -40.362 7.565-129.052 1.00 38.00 C +ATOM 7236 C TRP B 161 -40.034 9.016-129.374 1.00 39.03 C +ATOM 7237 O TRP B 161 -40.737 9.924-128.918 1.00 44.66 O +ATOM 7238 CB TRP B 161 -39.637 7.122-127.785 1.00 42.66 C +ATOM 7239 CG TRP B 161 -38.164 7.228-127.888 1.00 40.19 C +ATOM 7240 CD1 TRP B 161 -37.320 6.333-128.469 1.00 41.38 C +ATOM 7241 CD2 TRP B 161 -37.350 8.295-127.400 1.00 38.00 C +ATOM 7242 NE1 TRP B 161 -36.025 6.777-128.371 1.00 41.80 N +ATOM 7243 CE2 TRP B 161 -36.018 7.980-127.717 1.00 38.00 C +ATOM 7244 CE3 TRP B 161 -37.618 9.485-126.726 1.00 38.00 C +ATOM 7245 CZ2 TRP B 161 -34.957 8.814-127.385 1.00 38.00 C +ATOM 7246 CZ3 TRP B 161 -36.563 10.309-126.395 1.00 38.88 C +ATOM 7247 CH2 TRP B 161 -35.249 9.970-126.724 1.00 38.50 C +ATOM 7248 N VAL B 162 -38.993 9.256-130.175 1.00 38.00 N +ATOM 7249 CA VAL B 162 -38.660 10.622-130.569 1.00 40.02 C +ATOM 7250 C VAL B 162 -39.780 11.213-131.415 1.00 46.43 C +ATOM 7251 O VAL B 162 -40.261 12.324-131.160 1.00 47.35 O +ATOM 7252 CB VAL B 162 -37.312 10.656-131.309 1.00 42.40 C +ATOM 7253 CG1 VAL B 162 -36.931 12.087-131.663 1.00 38.00 C +ATOM 7254 CG2 VAL B 162 -36.241 10.016-130.461 1.00 40.24 C +ATOM 7255 N GLN B 163 -40.219 10.472-132.435 1.00 48.45 N +ATOM 7256 CA GLN B 163 -41.318 10.950-133.265 1.00 48.02 C +ATOM 7257 C GLN B 163 -42.614 11.035-132.469 1.00 46.85 C +ATOM 7258 O GLN B 163 -43.413 11.954-132.679 1.00 44.04 O +ATOM 7259 CB GLN B 163 -41.484 10.026-134.473 1.00 46.23 C +ATOM 7260 CG GLN B 163 -41.770 10.739-135.777 1.00 45.78 C +ATOM 7261 CD GLN B 163 -40.629 11.638-136.191 1.00 44.56 C +ATOM 7262 OE1 GLN B 163 -39.488 11.449-135.767 1.00 40.00 O +ATOM 7263 NE2 GLN B 163 -40.928 12.620-137.030 1.00 45.67 N +ATOM 7264 N PHE B 164 -42.811 10.122-131.517 1.00 46.68 N +ATOM 7265 CA PHE B 164 -43.993 10.186-130.668 1.00 41.91 C +ATOM 7266 C PHE B 164 -43.995 11.457-129.830 1.00 42.82 C +ATOM 7267 O PHE B 164 -45.023 12.135-129.722 1.00 44.30 O +ATOM 7268 CB PHE B 164 -44.050 8.946-129.775 1.00 38.44 C +ATOM 7269 CG PHE B 164 -45.028 9.056-128.642 1.00 43.36 C +ATOM 7270 CD1 PHE B 164 -46.378 9.239-128.887 1.00 45.92 C +ATOM 7271 CD2 PHE B 164 -44.597 8.974-127.328 1.00 42.05 C +ATOM 7272 CE1 PHE B 164 -47.278 9.337-127.841 1.00 45.18 C +ATOM 7273 CE2 PHE B 164 -45.492 9.071-126.282 1.00 38.00 C +ATOM 7274 CZ PHE B 164 -46.831 9.252-126.538 1.00 39.92 C +ATOM 7275 N HIS B 165 -42.839 11.818-129.268 1.00 41.01 N +ATOM 7276 CA HIS B 165 -42.758 12.990-128.401 1.00 41.24 C +ATOM 7277 C HIS B 165 -42.982 14.282-129.173 1.00 43.20 C +ATOM 7278 O HIS B 165 -43.718 15.167-128.722 1.00 45.84 O +ATOM 7279 CB HIS B 165 -41.403 13.024-127.702 1.00 42.44 C +ATOM 7280 CG HIS B 165 -41.234 11.963-126.665 1.00 41.37 C +ATOM 7281 ND1 HIS B 165 -40.145 11.913-125.824 1.00 40.19 N +ATOM 7282 CD2 HIS B 165 -42.016 10.908-126.335 1.00 38.09 C +ATOM 7283 CE1 HIS B 165 -40.264 10.874-125.018 1.00 44.73 C +ATOM 7284 NE2 HIS B 165 -41.389 10.246-125.309 1.00 39.98 N +ATOM 7285 N LEU B 166 -42.341 14.421-130.331 1.00 43.18 N +ATOM 7286 CA LEU B 166 -42.539 15.621-131.131 1.00 46.90 C +ATOM 7287 C LEU B 166 -43.926 15.681-131.751 1.00 53.67 C +ATOM 7288 O LEU B 166 -44.316 16.744-132.250 1.00 52.21 O +ATOM 7289 CB LEU B 166 -41.476 15.702-132.224 1.00 44.27 C +ATOM 7290 CG LEU B 166 -40.033 15.723-131.725 1.00 38.00 C +ATOM 7291 CD1 LEU B 166 -39.097 15.093-132.750 1.00 38.00 C +ATOM 7292 CD2 LEU B 166 -39.622 17.147-131.410 1.00 38.00 C +ATOM 7293 N GLY B 167 -44.673 14.576-131.720 1.00 51.43 N +ATOM 7294 CA GLY B 167 -46.010 14.460-132.258 1.00 51.17 C +ATOM 7295 C GLY B 167 -47.133 14.696-131.281 1.00 49.31 C +ATOM 7296 O GLY B 167 -48.299 14.501-131.641 1.00 50.50 O +ATOM 7297 N ILE B 168 -46.817 15.072-130.043 1.00 51.83 N +ATOM 7298 CA ILE B 168 -47.833 15.426-129.056 1.00 58.76 C +ATOM 7299 C ILE B 168 -48.220 16.886-129.261 1.00 58.87 C +ATOM 7300 O ILE B 168 -47.395 17.791-129.089 1.00 53.43 O +ATOM 7301 CB ILE B 168 -47.341 15.188-127.622 1.00 54.93 C +ATOM 7302 CG1 ILE B 168 -46.775 13.782-127.461 1.00 49.65 C +ATOM 7303 CG2 ILE B 168 -48.499 15.332-126.655 1.00 53.15 C +ATOM 7304 CD1 ILE B 168 -46.392 13.464-126.031 1.00 48.34 C +ATOM 7305 N ASN B 169 -49.478 17.113-129.615 1.00 60.67 N +ATOM 7306 CA ASN B 169 -50.032 18.422-129.921 1.00 54.83 C +ATOM 7307 C ASN B 169 -51.112 18.775-128.903 1.00 56.47 C +ATOM 7308 O ASN B 169 -51.402 18.014-127.976 1.00 57.08 O +ATOM 7309 CB ASN B 169 -50.583 18.448-131.352 1.00 55.76 C +ATOM 7310 CG ASN B 169 -51.450 17.235-131.675 1.00 59.65 C +ATOM 7311 OD1 ASN B 169 -51.459 16.244-130.943 1.00 62.47 O +ATOM 7312 ND2 ASN B 169 -52.165 17.301-132.788 1.00 60.31 N +ATOM 7313 N ARG B 170 -51.697 19.962-129.075 1.00 57.45 N +ATOM 7314 CA ARG B 170 -52.780 20.402-128.205 1.00 53.91 C +ATOM 7315 C ARG B 170 -54.018 19.518-128.320 1.00 52.35 C +ATOM 7316 O ARG B 170 -54.879 19.567-127.433 1.00 49.30 O +ATOM 7317 CB ARG B 170 -53.118 21.864-128.525 1.00 55.38 C +ATOM 7318 CG ARG B 170 -53.982 22.564-127.484 1.00 57.12 C +ATOM 7319 CD ARG B 170 -54.132 24.050-127.789 1.00 58.22 C +ATOM 7320 NE ARG B 170 -52.846 24.747-127.774 1.00 59.53 N +ATOM 7321 CZ ARG B 170 -52.342 25.366-126.710 1.00 59.27 C +ATOM 7322 NH1 ARG B 170 -53.015 25.374-125.566 1.00 60.45 N +ATOM 7323 NH2 ARG B 170 -51.165 25.976-126.786 1.00 52.27 N +ATOM 7324 N HIS B 171 -54.110 18.686-129.357 1.00 55.70 N +ATOM 7325 CA HIS B 171 -55.275 17.843-129.594 1.00 59.00 C +ATOM 7326 C HIS B 171 -55.149 16.458-128.982 1.00 51.88 C +ATOM 7327 O HIS B 171 -56.089 15.665-129.093 1.00 56.59 O +ATOM 7328 CB HIS B 171 -55.540 17.716-131.099 1.00 67.68 C +ATOM 7329 CG HIS B 171 -56.259 18.890-131.687 1.00 79.47 C +ATOM 7330 ND1 HIS B 171 -56.490 19.019-133.039 1.00 82.22 N +ATOM 7331 CD2 HIS B 171 -56.809 19.982-131.103 1.00 78.45 C +ATOM 7332 CE1 HIS B 171 -57.144 20.145-133.264 1.00 91.04 C +ATOM 7333 NE2 HIS B 171 -57.351 20.748-132.106 1.00 87.39 N +ATOM 7334 N GLY B 172 -54.028 16.137-128.365 1.00 48.77 N +ATOM 7335 CA GLY B 172 -53.911 14.870-127.673 1.00 52.54 C +ATOM 7336 C GLY B 172 -52.481 14.372-127.657 1.00 51.56 C +ATOM 7337 O GLY B 172 -51.554 15.029-128.124 1.00 50.43 O +ATOM 7338 N LEU B 173 -52.329 13.170-127.099 1.00 47.56 N +ATOM 7339 CA LEU B 173 -51.010 12.568-126.970 1.00 40.00 C +ATOM 7340 C LEU B 173 -50.471 12.124-128.321 1.00 43.63 C +ATOM 7341 O LEU B 173 -49.302 12.365-128.635 1.00 46.35 O +ATOM 7342 CB LEU B 173 -51.078 11.384-126.012 1.00 38.00 C +ATOM 7343 CG LEU B 173 -50.230 11.494-124.751 1.00 43.87 C +ATOM 7344 CD1 LEU B 173 -50.451 12.835-124.071 1.00 47.54 C +ATOM 7345 CD2 LEU B 173 -50.552 10.347-123.807 1.00 41.44 C +ATOM 7346 N TYR B 174 -51.309 11.492-129.137 1.00 46.29 N +ATOM 7347 CA TYR B 174 -50.897 10.977-130.434 1.00 47.97 C +ATOM 7348 C TYR B 174 -51.900 11.416-131.498 1.00 50.44 C +ATOM 7349 O TYR B 174 -52.899 12.081-131.209 1.00 50.72 O +ATOM 7350 CB TYR B 174 -50.741 9.451-130.403 1.00 42.07 C +ATOM 7351 CG TYR B 174 -51.907 8.686-129.820 1.00 38.18 C +ATOM 7352 CD1 TYR B 174 -52.120 8.639-128.451 1.00 39.94 C +ATOM 7353 CD2 TYR B 174 -52.770 7.973-130.639 1.00 39.98 C +ATOM 7354 CE1 TYR B 174 -53.179 7.931-127.915 1.00 44.55 C +ATOM 7355 CE2 TYR B 174 -53.826 7.251-130.111 1.00 44.56 C +ATOM 7356 CZ TYR B 174 -54.028 7.237-128.747 1.00 42.45 C +ATOM 7357 OH TYR B 174 -55.079 6.528-128.209 1.00 38.00 O +ATOM 7358 N SER B 175 -51.613 11.055-132.745 1.00 55.44 N +ATOM 7359 CA SER B 175 -52.441 11.424-133.883 1.00 53.82 C +ATOM 7360 C SER B 175 -53.494 10.354-134.172 1.00 51.53 C +ATOM 7361 O SER B 175 -53.353 9.185-133.803 1.00 48.39 O +ATOM 7362 CB SER B 175 -51.572 11.658-135.117 1.00 54.95 C +ATOM 7363 OG SER B 175 -50.380 12.345-134.772 1.00 53.91 O +ATOM 7364 N ARG B 176 -54.566 10.778-134.837 1.00 47.75 N +ATOM 7365 CA ARG B 176 -55.638 9.861-135.204 1.00 51.38 C +ATOM 7366 C ARG B 176 -55.167 8.924-136.311 1.00 54.55 C +ATOM 7367 O ARG B 176 -54.775 9.382-137.390 1.00 56.83 O +ATOM 7368 CB ARG B 176 -56.871 10.649-135.640 1.00 56.06 C +ATOM 7369 CG ARG B 176 -58.066 9.786-136.027 1.00 62.86 C +ATOM 7370 CD ARG B 176 -59.373 10.460-135.623 1.00 62.98 C +ATOM 7371 NE ARG B 176 -59.524 11.786-136.211 1.00 60.29 N +ATOM 7372 CZ ARG B 176 -60.449 12.665-135.838 1.00 59.78 C +ATOM 7373 NH1 ARG B 176 -61.304 12.365-134.869 1.00 53.48 N +ATOM 7374 NH2 ARG B 176 -60.513 13.847-136.433 1.00 65.60 N +ATOM 7375 N SER B 177 -55.212 7.617-136.048 1.00 52.09 N +ATOM 7376 CA SER B 177 -54.693 6.604-136.970 1.00 53.41 C +ATOM 7377 C SER B 177 -53.281 6.965-137.424 1.00 54.52 C +ATOM 7378 O SER B 177 -53.013 7.191-138.606 1.00 51.31 O +ATOM 7379 CB SER B 177 -55.618 6.414-138.177 1.00 55.94 C +ATOM 7380 OG SER B 177 -56.825 5.763-137.826 1.00 64.30 O +ATOM 7381 N SER B 178 -52.378 7.050-136.444 1.00 60.48 N +ATOM 7382 CA SER B 178 -50.997 7.475-136.664 1.00 58.53 C +ATOM 7383 C SER B 178 -50.125 6.268-136.990 1.00 52.15 C +ATOM 7384 O SER B 178 -50.153 5.274-136.252 1.00 48.74 O +ATOM 7385 CB SER B 178 -50.456 8.197-135.431 1.00 53.05 C +ATOM 7386 OG SER B 178 -49.061 8.447-135.517 1.00 49.89 O +ATOM 7387 N PRO B 179 -49.350 6.306-138.080 1.00 49.17 N +ATOM 7388 CA PRO B 179 -48.412 5.205-138.338 1.00 48.07 C +ATOM 7389 C PRO B 179 -47.273 5.173-137.343 1.00 54.25 C +ATOM 7390 O PRO B 179 -46.655 4.116-137.162 1.00 54.58 O +ATOM 7391 CB PRO B 179 -47.910 5.496-139.755 1.00 44.38 C +ATOM 7392 CG PRO B 179 -48.033 6.985-139.880 1.00 44.60 C +ATOM 7393 CD PRO B 179 -49.243 7.378-139.087 1.00 42.92 C +ATOM 7394 N VAL B 180 -47.003 6.294-136.671 1.00 55.98 N +ATOM 7395 CA VAL B 180 -45.981 6.322-135.633 1.00 45.98 C +ATOM 7396 C VAL B 180 -46.382 5.410-134.486 1.00 40.82 C +ATOM 7397 O VAL B 180 -45.579 4.603-134.001 1.00 39.97 O +ATOM 7398 CB VAL B 180 -45.756 7.769-135.150 1.00 41.97 C +ATOM 7399 CG1 VAL B 180 -44.836 7.801-133.943 1.00 41.20 C +ATOM 7400 CG2 VAL B 180 -45.197 8.629-136.270 1.00 42.35 C +ATOM 7401 N VAL B 181 -47.640 5.495-134.060 1.00 38.00 N +ATOM 7402 CA VAL B 181 -48.082 4.707-132.919 1.00 38.00 C +ATOM 7403 C VAL B 181 -48.029 3.220-133.233 1.00 38.00 C +ATOM 7404 O VAL B 181 -47.736 2.402-132.357 1.00 43.61 O +ATOM 7405 CB VAL B 181 -49.482 5.154-132.489 1.00 38.00 C +ATOM 7406 CG1 VAL B 181 -49.841 4.517-131.179 1.00 38.00 C +ATOM 7407 CG2 VAL B 181 -49.507 6.660-132.381 1.00 38.00 C +ATOM 7408 N SER B 182 -48.327 2.842-134.478 1.00 46.34 N +ATOM 7409 CA SER B 182 -48.231 1.436-134.869 1.00 48.27 C +ATOM 7410 C SER B 182 -46.799 0.923-134.766 1.00 45.12 C +ATOM 7411 O SER B 182 -46.570 -0.240-134.407 1.00 43.87 O +ATOM 7412 CB SER B 182 -48.765 1.245-136.286 1.00 47.93 C +ATOM 7413 OG SER B 182 -50.143 1.558-136.345 1.00 56.67 O +ATOM 7414 N LYS B 183 -45.824 1.759-135.139 1.00 46.28 N +ATOM 7415 CA LYS B 183 -44.418 1.399-134.978 1.00 44.39 C +ATOM 7416 C LYS B 183 -44.002 1.449-133.515 1.00 44.25 C +ATOM 7417 O LYS B 183 -43.264 0.577-133.041 1.00 44.77 O +ATOM 7418 CB LYS B 183 -43.548 2.338-135.813 1.00 43.49 C +ATOM 7419 CG LYS B 183 -42.067 2.025-135.809 1.00 38.00 C +ATOM 7420 CD LYS B 183 -41.815 0.683-136.473 1.00 43.58 C +ATOM 7421 CE LYS B 183 -40.368 0.532-136.905 1.00 47.12 C +ATOM 7422 NZ LYS B 183 -39.418 0.840-135.805 1.00 50.18 N +ATOM 7423 N LEU B 184 -44.483 2.460-132.784 1.00 41.68 N +ATOM 7424 CA LEU B 184 -44.157 2.598-131.370 1.00 38.00 C +ATOM 7425 C LEU B 184 -44.609 1.378-130.583 1.00 38.00 C +ATOM 7426 O LEU B 184 -43.874 0.866-129.734 1.00 38.00 O +ATOM 7427 CB LEU B 184 -44.792 3.871-130.814 1.00 38.00 C +ATOM 7428 CG LEU B 184 -44.585 4.138-129.327 1.00 38.00 C +ATOM 7429 CD1 LEU B 184 -43.114 4.123-129.007 1.00 38.00 C +ATOM 7430 CD2 LEU B 184 -45.188 5.475-128.952 1.00 38.00 C +ATOM 7431 N LEU B 185 -45.827 0.906-130.838 1.00 38.03 N +ATOM 7432 CA LEU B 185 -46.283 -0.306-130.173 1.00 38.00 C +ATOM 7433 C LEU B 185 -45.410 -1.493-130.542 1.00 47.41 C +ATOM 7434 O LEU B 185 -45.021 -2.281-129.672 1.00 51.52 O +ATOM 7435 CB LEU B 185 -47.733 -0.599-130.535 1.00 38.00 C +ATOM 7436 CG LEU B 185 -48.742 -0.067-129.534 1.00 40.32 C +ATOM 7437 CD1 LEU B 185 -49.422 1.150-130.095 1.00 42.69 C +ATOM 7438 CD2 LEU B 185 -49.750 -1.153-129.206 1.00 62.54 C +ATOM 7439 N GLN B 186 -45.074 -1.626-131.827 1.00 50.63 N +ATOM 7440 CA GLN B 186 -44.272 -2.765-132.253 1.00 51.99 C +ATOM 7441 C GLN B 186 -42.861 -2.703-131.692 1.00 46.61 C +ATOM 7442 O GLN B 186 -42.262 -3.747-131.413 1.00 47.84 O +ATOM 7443 CB GLN B 186 -44.233 -2.844-133.781 1.00 54.41 C +ATOM 7444 CG GLN B 186 -45.528 -3.321-134.412 1.00 56.58 C +ATOM 7445 CD GLN B 186 -45.934 -4.702-133.921 1.00 63.01 C +ATOM 7446 OE1 GLN B 186 -47.002 -4.870-133.324 1.00 69.83 O +ATOM 7447 NE2 GLN B 186 -45.079 -5.696-134.162 1.00 50.36 N +ATOM 7448 N ASP B 187 -42.328 -1.500-131.488 1.00 46.57 N +ATOM 7449 CA ASP B 187 -40.969 -1.385-130.971 1.00 50.58 C +ATOM 7450 C ASP B 187 -40.898 -1.783-129.502 1.00 44.09 C +ATOM 7451 O ASP B 187 -40.028 -2.564-129.104 1.00 42.05 O +ATOM 7452 CB ASP B 187 -40.445 0.032-131.187 1.00 51.00 C +ATOM 7453 CG ASP B 187 -40.095 0.297-132.633 1.00 44.81 C +ATOM 7454 OD1 ASP B 187 -40.349 -0.599-133.465 1.00 41.58 O +ATOM 7455 OD2 ASP B 187 -39.544 1.377-132.933 1.00 51.29 O +ATOM 7456 N MET B 188 -41.818 -1.277-128.683 1.00 38.00 N +ATOM 7457 CA MET B 188 -41.804 -1.654-127.278 1.00 38.00 C +ATOM 7458 C MET B 188 -42.033 -3.146-127.098 1.00 42.21 C +ATOM 7459 O MET B 188 -41.652 -3.701-126.061 1.00 41.43 O +ATOM 7460 CB MET B 188 -42.866 -0.871-126.510 1.00 38.00 C +ATOM 7461 CG MET B 188 -42.771 0.629-126.694 1.00 38.43 C +ATOM 7462 SD MET B 188 -43.691 1.540-125.452 1.00 38.00 S +ATOM 7463 CE MET B 188 -45.356 1.372-126.061 1.00 38.00 C +ATOM 7464 N ARG B 189 -42.591 -3.819-128.107 1.00 38.00 N +ATOM 7465 CA ARG B 189 -42.842 -5.246-127.976 1.00 38.00 C +ATOM 7466 C ARG B 189 -41.608 -6.069-128.307 1.00 39.24 C +ATOM 7467 O ARG B 189 -41.424 -7.147-127.735 1.00 40.51 O +ATOM 7468 CB ARG B 189 -44.003 -5.673-128.880 1.00 44.08 C +ATOM 7469 CG ARG B 189 -44.581 -7.049-128.540 1.00 52.49 C +ATOM 7470 CD ARG B 189 -45.133 -7.783-129.767 1.00 54.69 C +ATOM 7471 NE ARG B 189 -45.952 -6.919-130.613 1.00 65.33 N +ATOM 7472 CZ ARG B 189 -47.220 -6.605-130.358 1.00 67.73 C +ATOM 7473 NH1 ARG B 189 -47.812 -7.085-129.273 1.00 73.51 N +ATOM 7474 NH2 ARG B 189 -47.895 -5.808-131.182 1.00 57.86 N +ATOM 7475 N HIS B 190 -40.738 -5.579-129.190 1.00 40.94 N +ATOM 7476 CA HIS B 190 -39.648 -6.399-129.702 1.00 47.11 C +ATOM 7477 C HIS B 190 -38.255 -5.881-129.374 1.00 43.59 C +ATOM 7478 O HIS B 190 -37.342 -6.694-129.211 1.00 50.94 O +ATOM 7479 CB HIS B 190 -39.773 -6.564-131.226 1.00 46.95 C +ATOM 7480 CG HIS B 190 -41.051 -7.215-131.653 1.00 53.12 C +ATOM 7481 ND1 HIS B 190 -41.189 -8.582-131.751 1.00 62.85 N +ATOM 7482 CD2 HIS B 190 -42.244 -6.689-132.018 1.00 52.85 C +ATOM 7483 CE1 HIS B 190 -42.417 -8.872-132.144 1.00 67.69 C +ATOM 7484 NE2 HIS B 190 -43.076 -7.740-132.318 1.00 60.63 N +ATOM 7485 N PHE B 191 -38.067 -4.571-129.261 1.00 38.00 N +ATOM 7486 CA PHE B 191 -36.738 -4.030-129.021 1.00 38.00 C +ATOM 7487 C PHE B 191 -36.160 -4.606-127.734 1.00 40.43 C +ATOM 7488 O PHE B 191 -36.891 -4.795-126.754 1.00 45.15 O +ATOM 7489 CB PHE B 191 -36.789 -2.509-128.927 1.00 38.00 C +ATOM 7490 CG PHE B 191 -36.712 -1.821-130.249 1.00 39.37 C +ATOM 7491 CD1 PHE B 191 -37.536 -2.202-131.291 1.00 47.06 C +ATOM 7492 CD2 PHE B 191 -35.838 -0.767-130.443 1.00 39.07 C +ATOM 7493 CE1 PHE B 191 -37.475 -1.564-132.506 1.00 42.40 C +ATOM 7494 CE2 PHE B 191 -35.776 -0.120-131.654 1.00 42.24 C +ATOM 7495 CZ PHE B 191 -36.597 -0.516-132.687 1.00 44.10 C +ATOM 7496 N PRO B 192 -34.869 -4.913-127.702 1.00 44.09 N +ATOM 7497 CA PRO B 192 -34.276 -5.450-126.477 1.00 52.28 C +ATOM 7498 C PRO B 192 -34.103 -4.358-125.432 1.00 46.45 C +ATOM 7499 O PRO B 192 -34.002 -3.167-125.738 1.00 42.58 O +ATOM 7500 CB PRO B 192 -32.922 -5.989-126.950 1.00 46.72 C +ATOM 7501 CG PRO B 192 -32.567 -5.090-128.088 1.00 38.00 C +ATOM 7502 CD PRO B 192 -33.871 -4.756-128.773 1.00 41.39 C +ATOM 7503 N THR B 193 -34.079 -4.785-124.175 1.00 40.32 N +ATOM 7504 CA THR B 193 -33.883 -3.872-123.064 1.00 38.00 C +ATOM 7505 C THR B 193 -32.398 -3.696-122.794 1.00 38.08 C +ATOM 7506 O THR B 193 -31.612 -4.639-122.922 1.00 39.40 O +ATOM 7507 CB THR B 193 -34.579 -4.383-121.808 1.00 38.00 C +ATOM 7508 OG1 THR B 193 -34.144 -5.718-121.537 1.00 38.00 O +ATOM 7509 CG2 THR B 193 -36.070 -4.374-122.010 1.00 38.00 C +ATOM 7510 N ILE B 194 -32.017 -2.476-122.434 1.00 38.00 N +ATOM 7511 CA ILE B 194 -30.628 -2.157-122.133 1.00 38.00 C +ATOM 7512 C ILE B 194 -30.426 -1.679-120.707 1.00 38.00 C +ATOM 7513 O ILE B 194 -29.271 -1.501-120.293 1.00 38.00 O +ATOM 7514 CB ILE B 194 -30.072 -1.109-123.116 1.00 38.00 C +ATOM 7515 CG1 ILE B 194 -30.738 0.243-122.875 1.00 38.00 C +ATOM 7516 CG2 ILE B 194 -30.318 -1.542-124.546 1.00 45.97 C +ATOM 7517 CD1 ILE B 194 -30.259 1.310-123.816 1.00 38.00 C +ATOM 7518 N SER B 195 -31.495 -1.482-119.940 1.00 38.00 N +ATOM 7519 CA SER B 195 -31.426 -0.863-118.626 1.00 38.00 C +ATOM 7520 C SER B 195 -32.766 -1.040-117.922 1.00 39.62 C +ATOM 7521 O SER B 195 -33.819 -1.013-118.563 1.00 45.10 O +ATOM 7522 CB SER B 195 -31.067 0.627-118.776 1.00 38.00 C +ATOM 7523 OG SER B 195 -31.543 1.438-117.716 1.00 50.07 O +ATOM 7524 N ALA B 196 -32.716 -1.190-116.597 1.00 38.00 N +ATOM 7525 CA ALA B 196 -33.921 -1.279-115.778 1.00 38.00 C +ATOM 7526 C ALA B 196 -33.627 -0.667-114.418 1.00 38.00 C +ATOM 7527 O ALA B 196 -32.579 -0.946-113.828 1.00 38.00 O +ATOM 7528 CB ALA B 196 -34.399 -2.726-115.622 1.00 38.00 C +ATOM 7529 N ASP B 197 -34.539 0.181-113.940 1.00 38.00 N +ATOM 7530 CA ASP B 197 -34.389 0.828-112.642 1.00 38.00 C +ATOM 7531 C ASP B 197 -35.688 0.758-111.843 1.00 39.22 C +ATOM 7532 O ASP B 197 -36.652 0.109-112.262 1.00 39.37 O +ATOM 7533 CB ASP B 197 -33.950 2.283-112.825 1.00 45.72 C +ATOM 7534 CG ASP B 197 -33.214 2.834-111.613 1.00 51.38 C +ATOM 7535 OD1 ASP B 197 -33.503 2.386-110.484 1.00 48.99 O +ATOM 7536 OD2 ASP B 197 -32.347 3.718-111.789 1.00 58.53 O +ATOM 7537 N TYR B 198 -35.739 1.466-110.716 1.00 44.98 N +ATOM 7538 CA TYR B 198 -36.891 1.451-109.825 1.00 46.83 C +ATOM 7539 C TYR B 198 -37.864 2.582-110.098 1.00 44.84 C +ATOM 7540 O TYR B 198 -38.925 2.629-109.466 1.00 42.83 O +ATOM 7541 CB TYR B 198 -36.422 1.531-108.365 1.00 47.81 C +ATOM 7542 CG TYR B 198 -36.446 0.219-107.610 1.00 44.97 C +ATOM 7543 CD1 TYR B 198 -37.552 -0.616-107.662 1.00 43.54 C +ATOM 7544 CD2 TYR B 198 -35.360 -0.184-106.845 1.00 47.73 C +ATOM 7545 CE1 TYR B 198 -37.580 -1.814-106.971 1.00 44.98 C +ATOM 7546 CE2 TYR B 198 -35.377 -1.386-106.153 1.00 47.79 C +ATOM 7547 CZ TYR B 198 -36.492 -2.196-106.221 1.00 47.41 C +ATOM 7548 OH TYR B 198 -36.530 -3.392-105.540 1.00 51.40 O +ATOM 7549 N SER B 199 -37.536 3.475-111.033 1.00 46.93 N +ATOM 7550 CA SER B 199 -38.324 4.664-111.342 1.00 55.03 C +ATOM 7551 C SER B 199 -38.317 5.659-110.192 1.00 59.99 C +ATOM 7552 O SER B 199 -37.990 5.314-109.052 1.00 63.62 O +ATOM 7553 CB SER B 199 -39.773 4.297-111.687 1.00 61.36 C +ATOM 7554 OG SER B 199 -40.519 3.998-110.514 1.00 45.18 O +ATOM 7555 N GLN B 200 -38.707 6.895-110.479 1.00 57.90 N +ATOM 7556 CA GLN B 200 -38.928 7.878-109.432 1.00 55.61 C +ATOM 7557 C GLN B 200 -40.225 7.531-108.716 1.00 54.02 C +ATOM 7558 O GLN B 200 -40.701 6.398-108.822 1.00 60.80 O +ATOM 7559 CB GLN B 200 -38.988 9.276-110.033 1.00 65.83 C +ATOM 7560 CG GLN B 200 -38.289 10.315-109.213 1.00 75.93 C +ATOM 7561 CD GLN B 200 -36.807 10.398-109.512 1.00 75.73 C +ATOM 7562 OE1 GLN B 200 -36.116 11.267-108.980 1.00 83.19 O +ATOM 7563 NE2 GLN B 200 -36.310 9.501-110.365 1.00 57.54 N +ATOM 7564 N ASP B 201 -40.797 8.477-107.973 1.00 48.54 N +ATOM 7565 CA ASP B 201 -42.073 8.274-107.285 1.00 58.45 C +ATOM 7566 C ASP B 201 -41.947 7.192-106.210 1.00 63.04 C +ATOM 7567 O ASP B 201 -42.423 7.375-105.083 1.00 67.69 O +ATOM 7568 CB ASP B 201 -43.184 8.000-108.326 1.00 57.13 C +ATOM 7569 CG ASP B 201 -43.827 6.623-108.204 1.00 55.91 C +ATOM 7570 OD1 ASP B 201 -44.687 6.439-107.317 1.00 67.41 O +ATOM 7571 OD2 ASP B 201 -43.515 5.741-109.035 1.00 50.57 O +ATOM 7572 N GLU B 202 -41.300 6.075-106.528 1.00 59.72 N +ATOM 7573 CA GLU B 202 -40.570 5.325-105.519 1.00 48.47 C +ATOM 7574 C GLU B 202 -39.185 5.965-105.448 1.00 53.49 C +ATOM 7575 O GLU B 202 -39.004 7.095-105.911 1.00 57.93 O +ATOM 7576 CB GLU B 202 -40.524 3.835-105.868 1.00 48.82 C +ATOM 7577 CG GLU B 202 -40.117 2.935-104.700 1.00 61.47 C +ATOM 7578 CD GLU B 202 -38.732 2.327-104.875 1.00 68.34 C +ATOM 7579 OE1 GLU B 202 -38.448 1.802-105.971 1.00 69.69 O +ATOM 7580 OE2 GLU B 202 -37.928 2.373-103.917 1.00 65.79 O +ATOM 7581 N LYS B 203 -38.191 5.256-104.913 1.00 50.81 N +ATOM 7582 CA LYS B 203 -36.818 5.745-104.894 1.00 58.27 C +ATOM 7583 C LYS B 203 -36.712 7.008-104.048 1.00 50.55 C +ATOM 7584 O LYS B 203 -35.888 7.085-103.131 1.00 45.44 O +ATOM 7585 CB LYS B 203 -36.341 6.003-106.329 1.00 58.33 C +ATOM 7586 CG LYS B 203 -34.870 5.780-106.577 1.00 56.92 C +ATOM 7587 CD LYS B 203 -34.614 5.547-108.053 1.00 53.58 C +ATOM 7588 CE LYS B 203 -33.158 5.759-108.400 1.00 50.05 C +ATOM 7589 NZ LYS B 203 -32.859 5.361-109.801 1.00 51.96 N +ATOM 7590 N ALA B 204 -37.549 8.000-104.354 1.00 49.91 N +ATOM 7591 CA ALA B 204 -37.670 9.193-103.532 1.00 49.41 C +ATOM 7592 C ALA B 204 -38.395 8.924-102.224 1.00 45.71 C +ATOM 7593 O ALA B 204 -38.492 9.832-101.393 1.00 48.72 O +ATOM 7594 CB ALA B 204 -38.392 10.298-104.305 1.00 69.93 C +ATOM 7595 N LEU B 205 -38.916 7.714-102.023 1.00 41.79 N +ATOM 7596 CA LEU B 205 -39.443 7.381-100.710 1.00 38.95 C +ATOM 7597 C LEU B 205 -38.328 7.200 -99.693 1.00 41.04 C +ATOM 7598 O LEU B 205 -38.595 7.249 -98.489 1.00 51.32 O +ATOM 7599 CB LEU B 205 -40.297 6.117-100.770 1.00 38.00 C +ATOM 7600 CG LEU B 205 -41.633 6.265-101.492 1.00 44.56 C +ATOM 7601 CD1 LEU B 205 -42.486 5.028-101.290 1.00 46.59 C +ATOM 7602 CD2 LEU B 205 -42.361 7.507-101.035 1.00 51.64 C +ATOM 7603 N LEU B 206 -37.093 6.986-100.157 1.00 39.35 N +ATOM 7604 CA LEU B 206 -35.916 6.856 -99.306 1.00 38.00 C +ATOM 7605 C LEU B 206 -36.044 5.634 -98.410 1.00 38.00 C +ATOM 7606 O LEU B 206 -35.320 4.650 -98.585 1.00 38.00 O +ATOM 7607 CB LEU B 206 -35.707 8.119 -98.468 1.00 38.16 C +ATOM 7608 CG LEU B 206 -35.336 9.377 -99.253 1.00 39.83 C +ATOM 7609 CD1 LEU B 206 -34.891 10.494 -98.316 1.00 51.66 C +ATOM 7610 CD2 LEU B 206 -34.263 9.073-100.272 1.00 41.43 C +ATOM 7611 N GLY B 207 -36.968 5.691 -97.453 1.00 38.76 N +ATOM 7612 CA GLY B 207 -37.237 4.572 -96.573 1.00 39.31 C +ATOM 7613 C GLY B 207 -37.918 3.447 -97.320 1.00 38.00 C +ATOM 7614 O GLY B 207 -37.249 2.729 -98.068 1.00 38.00 O +ATOM 7615 N ALA B 208 -39.228 3.270 -97.157 1.00 38.00 N +ATOM 7616 CA ALA B 208 -40.079 4.012 -96.235 1.00 38.00 C +ATOM 7617 C ALA B 208 -41.319 3.170 -96.024 1.00 43.31 C +ATOM 7618 O ALA B 208 -42.373 3.481 -96.569 1.00 46.26 O +ATOM 7619 CB ALA B 208 -40.461 5.373 -96.783 1.00 38.00 C +ATOM 7620 N CYS B 209 -41.191 2.090 -95.266 1.00 48.19 N +ATOM 7621 CA CYS B 209 -42.245 1.093 -95.136 1.00 50.66 C +ATOM 7622 C CYS B 209 -42.898 1.233 -93.761 1.00 57.34 C +ATOM 7623 O CYS B 209 -42.247 1.011 -92.735 1.00 61.00 O +ATOM 7624 CB CYS B 209 -41.670 -0.305 -95.336 1.00 49.86 C +ATOM 7625 SG CYS B 209 -42.785 -1.473 -96.137 1.00 98.41 S +ATOM 7626 N ASP B 210 -44.178 1.607 -93.741 1.00 59.75 N +ATOM 7627 CA ASP B 210 -44.982 1.687 -92.517 1.00 62.39 C +ATOM 7628 C ASP B 210 -46.117 0.676 -92.649 1.00 56.49 C +ATOM 7629 O ASP B 210 -47.167 0.981 -93.229 1.00 59.54 O +ATOM 7630 CB ASP B 210 -45.525 3.103 -92.290 1.00 66.93 C +ATOM 7631 CG ASP B 210 -46.209 3.274 -90.923 1.00 72.21 C +ATOM 7632 OD1 ASP B 210 -46.183 2.331 -90.099 1.00 77.44 O +ATOM 7633 OD2 ASP B 210 -46.792 4.355 -90.679 1.00 64.60 O +ATOM 7634 N CYS B 211 -45.923 -0.524 -92.101 1.00 48.62 N +ATOM 7635 CA CYS B 211 -46.938 -1.562 -92.243 1.00 53.23 C +ATOM 7636 C CYS B 211 -48.274 -1.185 -91.618 1.00 52.57 C +ATOM 7637 O CYS B 211 -49.277 -1.843 -91.907 1.00 52.23 O +ATOM 7638 CB CYS B 211 -46.417 -2.875 -91.650 1.00 70.52 C +ATOM 7639 SG CYS B 211 -44.948 -3.557 -92.494 1.00 98.55 S +ATOM 7640 N THR B 212 -48.326 -0.127 -90.810 1.00 57.38 N +ATOM 7641 CA THR B 212 -49.597 0.340 -90.267 1.00 61.65 C +ATOM 7642 C THR B 212 -50.383 1.156 -91.286 1.00 64.70 C +ATOM 7643 O THR B 212 -51.621 1.125 -91.288 1.00 66.20 O +ATOM 7644 CB THR B 212 -49.335 1.156 -89.001 1.00 64.48 C +ATOM 7645 OG1 THR B 212 -48.866 0.276 -87.975 1.00 71.65 O +ATOM 7646 CG2 THR B 212 -50.597 1.854 -88.524 1.00 70.83 C +ATOM 7647 N GLN B 213 -49.687 1.879 -92.155 1.00 64.94 N +ATOM 7648 CA GLN B 213 -50.339 2.631 -93.216 1.00 64.83 C +ATOM 7649 C GLN B 213 -51.157 1.700 -94.101 1.00 60.19 C +ATOM 7650 O GLN B 213 -50.613 0.797 -94.744 1.00 54.83 O +ATOM 7651 CB GLN B 213 -49.284 3.367 -94.036 1.00 59.66 C +ATOM 7652 CG GLN B 213 -49.724 4.700 -94.589 1.00 57.08 C +ATOM 7653 CD GLN B 213 -48.577 5.433 -95.246 1.00 58.28 C +ATOM 7654 OE1 GLN B 213 -47.478 4.888 -95.382 1.00 49.89 O +ATOM 7655 NE2 GLN B 213 -48.822 6.674 -95.658 1.00 61.62 N +ATOM 7656 N ILE B 214 -52.472 1.913 -94.119 1.00 64.25 N +ATOM 7657 CA ILE B 214 -53.339 1.080 -94.943 1.00 61.02 C +ATOM 7658 C ILE B 214 -53.272 1.518 -96.398 1.00 55.40 C +ATOM 7659 O ILE B 214 -53.230 0.685 -97.308 1.00 52.69 O +ATOM 7660 CB ILE B 214 -54.778 1.109 -94.401 1.00 61.91 C +ATOM 7661 CG1 ILE B 214 -54.801 0.594 -92.965 1.00 55.06 C +ATOM 7662 CG2 ILE B 214 -55.698 0.269 -95.277 1.00 55.02 C +ATOM 7663 CD1 ILE B 214 -56.168 0.603 -92.350 1.00 64.25 C +ATOM 7664 N VAL B 215 -53.265 2.826 -96.642 1.00 51.07 N +ATOM 7665 CA VAL B 215 -53.144 3.346 -97.997 1.00 47.38 C +ATOM 7666 C VAL B 215 -51.760 3.955 -98.164 1.00 52.16 C +ATOM 7667 O VAL B 215 -51.602 5.181 -98.199 1.00 52.60 O +ATOM 7668 CB VAL B 215 -54.248 4.369 -98.306 1.00 46.04 C +ATOM 7669 CG1 VAL B 215 -54.311 4.629 -99.790 1.00 46.29 C +ATOM 7670 CG2 VAL B 215 -55.581 3.857 -97.802 1.00 50.54 C +ATOM 7671 N LYS B 216 -50.752 3.094 -98.247 1.00 54.92 N +ATOM 7672 CA LYS B 216 -49.388 3.529 -98.501 1.00 52.00 C +ATOM 7673 C LYS B 216 -49.292 4.216 -99.865 1.00 47.89 C +ATOM 7674 O LYS B 216 -50.120 3.973-100.751 1.00 46.61 O +ATOM 7675 CB LYS B 216 -48.442 2.331 -98.420 1.00 47.24 C +ATOM 7676 CG LYS B 216 -49.126 0.988 -98.627 1.00 45.00 C +ATOM 7677 CD LYS B 216 -48.183 -0.163 -98.323 1.00 47.06 C +ATOM 7678 CE LYS B 216 -47.929 -0.306 -96.835 1.00 38.13 C +ATOM 7679 NZ LYS B 216 -49.090 -0.932 -96.153 1.00 43.89 N +ATOM 7680 N PRO B 217 -48.307 5.100-100.055 1.00 45.04 N +ATOM 7681 CA PRO B 217 -48.260 5.907-101.280 1.00 53.84 C +ATOM 7682 C PRO B 217 -48.141 5.048-102.530 1.00 58.94 C +ATOM 7683 O PRO B 217 -47.765 3.876-102.478 1.00 61.91 O +ATOM 7684 CB PRO B 217 -47.007 6.770-101.088 1.00 51.57 C +ATOM 7685 CG PRO B 217 -46.169 6.005-100.120 1.00 38.27 C +ATOM 7686 CD PRO B 217 -47.148 5.368 -99.187 1.00 41.46 C +ATOM 7687 N SER B 218 -48.441 5.662-103.677 1.00 63.54 N +ATOM 7688 CA SER B 218 -48.437 4.939-104.943 1.00 70.91 C +ATOM 7689 C SER B 218 -47.006 4.666-105.392 1.00 63.33 C +ATOM 7690 O SER B 218 -46.761 4.387-106.569 1.00 74.63 O +ATOM 7691 CB SER B 218 -49.205 5.721-106.019 1.00 76.50 C +ATOM 7692 OG SER B 218 -49.302 4.992-107.236 1.00 80.83 O +ATOM 7693 N GLY B 219 -46.059 4.716-104.463 1.00 50.57 N +ATOM 7694 CA GLY B 219 -44.685 4.456-104.820 1.00 49.68 C +ATOM 7695 C GLY B 219 -44.240 3.077-104.399 1.00 54.93 C +ATOM 7696 O GLY B 219 -43.232 2.574-104.896 1.00 65.41 O +ATOM 7697 N VAL B 220 -45.015 2.418-103.544 1.00 55.51 N +ATOM 7698 CA VAL B 220 -44.641 1.086-103.083 1.00 51.09 C +ATOM 7699 C VAL B 220 -45.394 0.049-103.895 1.00 54.34 C +ATOM 7700 O VAL B 220 -45.927 -0.916-103.344 1.00 65.06 O +ATOM 7701 CB VAL B 220 -44.915 0.899-101.580 1.00 47.55 C +ATOM 7702 CG1 VAL B 220 -43.928 1.701-100.768 1.00 60.32 C +ATOM 7703 CG2 VAL B 220 -46.334 1.307-101.246 1.00 48.55 C +ATOM 7704 N HIS B 221 -45.440 0.233-105.204 1.00 45.67 N +ATOM 7705 CA HIS B 221 -46.114 -0.704-106.082 1.00 43.68 C +ATOM 7706 C HIS B 221 -45.101 -1.252-107.077 1.00 45.17 C +ATOM 7707 O HIS B 221 -44.131 -0.574-107.433 1.00 46.43 O +ATOM 7708 CB HIS B 221 -47.297 -0.037-106.798 1.00 50.89 C +ATOM 7709 CG HIS B 221 -48.423 0.343-105.882 1.00 54.52 C +ATOM 7710 ND1 HIS B 221 -48.754 -0.386-104.760 1.00 49.02 N +ATOM 7711 CD2 HIS B 221 -49.281 1.391-105.912 1.00 55.85 C +ATOM 7712 CE1 HIS B 221 -49.774 0.188-104.147 1.00 43.21 C +ATOM 7713 NE2 HIS B 221 -50.111 1.269-104.824 1.00 44.95 N +ATOM 7714 N LEU B 222 -45.304 -2.505-107.479 1.00 45.60 N +ATOM 7715 CA LEU B 222 -44.360 -3.204-108.351 1.00 38.00 C +ATOM 7716 C LEU B 222 -44.473 -2.655-109.764 1.00 38.00 C +ATOM 7717 O LEU B 222 -45.374 -3.025-110.520 1.00 38.00 O +ATOM 7718 CB LEU B 222 -44.623 -4.704-108.332 1.00 38.76 C +ATOM 7719 CG LEU B 222 -43.375 -5.578-108.227 1.00 39.45 C +ATOM 7720 CD1 LEU B 222 -43.757 -7.043-108.342 1.00 47.74 C +ATOM 7721 CD2 LEU B 222 -42.335 -5.202-109.267 1.00 38.00 C +ATOM 7722 N LYS B 223 -43.534 -1.787-110.128 1.00 38.00 N +ATOM 7723 CA LYS B 223 -43.434 -1.251-111.475 1.00 38.00 C +ATOM 7724 C LYS B 223 -41.995 -0.814-111.694 1.00 38.00 C +ATOM 7725 O LYS B 223 -41.377 -0.223-110.804 1.00 39.10 O +ATOM 7726 CB LYS B 223 -44.392 -0.075-111.689 1.00 38.00 C +ATOM 7727 CG LYS B 223 -44.100 1.135-110.814 1.00 39.32 C +ATOM 7728 CD LYS B 223 -45.141 2.221-111.005 1.00 42.67 C +ATOM 7729 CE LYS B 223 -45.164 3.168-109.818 1.00 41.22 C +ATOM 7730 NZ LYS B 223 -46.248 4.179-109.935 1.00 43.69 N +ATOM 7731 N LEU B 224 -41.470 -1.112-112.877 1.00 38.76 N +ATOM 7732 CA LEU B 224 -40.102 -0.778-113.241 1.00 38.00 C +ATOM 7733 C LEU B 224 -40.116 0.073-114.499 1.00 38.00 C +ATOM 7734 O LEU B 224 -41.124 0.167-115.203 1.00 40.08 O +ATOM 7735 CB LEU B 224 -39.262 -2.041-113.460 1.00 38.00 C +ATOM 7736 CG LEU B 224 -39.328 -3.064-112.330 1.00 38.00 C +ATOM 7737 CD1 LEU B 224 -38.527 -4.305-112.664 1.00 38.00 C +ATOM 7738 CD2 LEU B 224 -38.819 -2.428-111.066 1.00 38.77 C +ATOM 7739 N VAL B 225 -38.981 0.698-114.782 1.00 38.00 N +ATOM 7740 CA VAL B 225 -38.820 1.519-115.974 1.00 38.00 C +ATOM 7741 C VAL B 225 -37.723 0.895-116.828 1.00 39.03 C +ATOM 7742 O VAL B 225 -36.568 0.792-116.396 1.00 45.04 O +ATOM 7743 CB VAL B 225 -38.513 2.981-115.613 1.00 38.00 C +ATOM 7744 CG1 VAL B 225 -37.565 3.041-114.437 1.00 38.00 C +ATOM 7745 CG2 VAL B 225 -37.944 3.722-116.811 1.00 40.16 C +ATOM 7746 N LEU B 226 -38.084 0.475-118.033 1.00 38.00 N +ATOM 7747 CA LEU B 226 -37.182 -0.229-118.926 1.00 38.00 C +ATOM 7748 C LEU B 226 -36.678 0.719-120.010 1.00 46.29 C +ATOM 7749 O LEU B 226 -37.355 1.683-120.377 1.00 48.67 O +ATOM 7750 CB LEU B 226 -37.907 -1.420-119.557 1.00 38.00 C +ATOM 7751 CG LEU B 226 -37.980 -2.756-118.811 1.00 38.00 C +ATOM 7752 CD1 LEU B 226 -38.131 -2.597-117.312 1.00 38.00 C +ATOM 7753 CD2 LEU B 226 -39.143 -3.566-119.354 1.00 38.00 C +ATOM 7754 N ARG B 227 -35.479 0.443-120.523 1.00 47.22 N +ATOM 7755 CA ARG B 227 -34.903 1.206-121.624 1.00 43.66 C +ATOM 7756 C ARG B 227 -34.583 0.260-122.765 1.00 47.96 C +ATOM 7757 O ARG B 227 -34.061 -0.838-122.546 1.00 43.85 O +ATOM 7758 CB ARG B 227 -33.621 1.949-121.238 1.00 40.32 C +ATOM 7759 CG ARG B 227 -33.687 2.700-119.936 1.00 61.52 C +ATOM 7760 CD ARG B 227 -32.735 3.884-119.939 1.00 69.10 C +ATOM 7761 NE ARG B 227 -33.153 4.885-120.916 1.00 53.91 N +ATOM 7762 CZ ARG B 227 -32.848 6.175-120.834 1.00 49.03 C +ATOM 7763 NH1 ARG B 227 -32.126 6.622-119.817 1.00 51.04 N +ATOM 7764 NH2 ARG B 227 -33.280 7.020-121.758 1.00 48.18 N +ATOM 7765 N PHE B 228 -34.897 0.690-123.981 1.00 49.03 N +ATOM 7766 CA PHE B 228 -34.702 -0.121-125.168 1.00 40.75 C +ATOM 7767 C PHE B 228 -33.544 0.417-125.994 1.00 38.00 C +ATOM 7768 O PHE B 228 -33.035 1.517-125.766 1.00 38.00 O +ATOM 7769 CB PHE B 228 -35.988 -0.165-125.987 1.00 39.28 C +ATOM 7770 CG PHE B 228 -37.198 -0.486-125.167 1.00 44.13 C +ATOM 7771 CD1 PHE B 228 -37.472 -1.793-124.792 1.00 41.15 C +ATOM 7772 CD2 PHE B 228 -38.051 0.518-124.750 1.00 43.68 C +ATOM 7773 CE1 PHE B 228 -38.583 -2.089-124.032 1.00 38.00 C +ATOM 7774 CE2 PHE B 228 -39.161 0.224-123.989 1.00 39.07 C +ATOM 7775 CZ PHE B 228 -39.425 -1.080-123.633 1.00 38.00 C +ATOM 7776 N SER B 229 -33.162 -0.369-126.998 1.00 38.00 N +ATOM 7777 CA SER B 229 -31.984 -0.045-127.788 1.00 38.00 C +ATOM 7778 C SER B 229 -32.116 1.276-128.537 1.00 38.00 C +ATOM 7779 O SER B 229 -31.095 1.883-128.873 1.00 41.34 O +ATOM 7780 CB SER B 229 -31.699 -1.189-128.756 1.00 40.08 C +ATOM 7781 OG SER B 229 -32.835 -1.443-129.556 1.00 44.72 O +ATOM 7782 N ASP B 230 -33.333 1.756-128.787 1.00 38.58 N +ATOM 7783 CA ASP B 230 -33.501 3.054-129.426 1.00 38.00 C +ATOM 7784 C ASP B 230 -33.487 4.198-128.426 1.00 38.00 C +ATOM 7785 O ASP B 230 -33.838 5.321-128.796 1.00 38.00 O +ATOM 7786 CB ASP B 230 -34.802 3.098-130.244 1.00 40.90 C +ATOM 7787 CG ASP B 230 -36.060 2.948-129.389 1.00 44.85 C +ATOM 7788 OD1 ASP B 230 -35.951 2.685-128.173 1.00 50.37 O +ATOM 7789 OD2 ASP B 230 -37.172 3.117-129.937 1.00 43.80 O +ATOM 7790 N PHE B 231 -33.074 3.935-127.184 1.00 41.76 N +ATOM 7791 CA PHE B 231 -32.932 4.854-126.058 1.00 44.48 C +ATOM 7792 C PHE B 231 -34.272 5.141-125.369 1.00 45.99 C +ATOM 7793 O PHE B 231 -34.273 5.740-124.292 1.00 46.89 O +ATOM 7794 CB PHE B 231 -32.269 6.193-126.446 1.00 47.11 C +ATOM 7795 CG PHE B 231 -31.722 6.971-125.282 1.00 45.97 C +ATOM 7796 CD1 PHE B 231 -30.596 6.540-124.605 1.00 51.76 C +ATOM 7797 CD2 PHE B 231 -32.338 8.140-124.871 1.00 49.50 C +ATOM 7798 CE1 PHE B 231 -30.097 7.262-123.535 1.00 57.42 C +ATOM 7799 CE2 PHE B 231 -31.846 8.864-123.809 1.00 55.26 C +ATOM 7800 CZ PHE B 231 -30.723 8.426-123.138 1.00 56.63 C +ATOM 7801 N GLY B 232 -35.405 4.735-125.940 1.00 47.89 N +ATOM 7802 CA GLY B 232 -36.687 5.040-125.338 1.00 49.36 C +ATOM 7803 C GLY B 232 -36.938 4.280-124.049 1.00 48.86 C +ATOM 7804 O GLY B 232 -36.274 3.296-123.724 1.00 52.81 O +ATOM 7805 N LYS B 233 -37.933 4.753-123.301 1.00 43.26 N +ATOM 7806 CA LYS B 233 -38.303 4.161-122.025 1.00 43.75 C +ATOM 7807 C LYS B 233 -39.783 3.806-122.038 1.00 42.12 C +ATOM 7808 O LYS B 233 -40.547 4.254-122.897 1.00 47.29 O +ATOM 7809 CB LYS B 233 -37.986 5.102-120.851 1.00 48.01 C +ATOM 7810 CG LYS B 233 -36.503 5.400-120.665 1.00 45.21 C +ATOM 7811 CD LYS B 233 -36.242 6.216-119.405 1.00 38.79 C +ATOM 7812 CE LYS B 233 -36.332 7.706-119.696 1.00 47.55 C +ATOM 7813 NZ LYS B 233 -35.911 8.575-118.561 1.00 51.49 N +ATOM 7814 N ALA B 234 -40.176 2.988-121.065 1.00 38.00 N +ATOM 7815 CA ALA B 234 -41.544 2.513-120.945 1.00 38.00 C +ATOM 7816 C ALA B 234 -41.742 1.976-119.540 1.00 38.00 C +ATOM 7817 O ALA B 234 -40.848 1.332-118.988 1.00 38.60 O +ATOM 7818 CB ALA B 234 -41.863 1.425-121.971 1.00 38.00 C +ATOM 7819 N MET B 235 -42.915 2.241-118.977 1.00 39.78 N +ATOM 7820 CA MET B 235 -43.251 1.822-117.623 1.00 38.00 C +ATOM 7821 C MET B 235 -43.789 0.397-117.655 1.00 38.00 C +ATOM 7822 O MET B 235 -44.831 0.134-118.262 1.00 38.00 O +ATOM 7823 CB MET B 235 -44.276 2.777-117.017 1.00 38.00 C +ATOM 7824 CG MET B 235 -44.573 2.533-115.555 1.00 43.41 C +ATOM 7825 SD MET B 235 -43.149 2.825-114.500 1.00 40.90 S +ATOM 7826 CE MET B 235 -42.837 4.555-114.841 1.00 47.94 C +ATOM 7827 N PHE B 236 -43.081 -0.515-117.003 1.00 38.00 N +ATOM 7828 CA PHE B 236 -43.411 -1.932-117.032 1.00 38.00 C +ATOM 7829 C PHE B 236 -44.246 -2.288-115.809 1.00 38.00 C +ATOM 7830 O PHE B 236 -43.852 -1.998-114.676 1.00 38.00 O +ATOM 7831 CB PHE B 236 -42.147 -2.785-117.092 1.00 38.00 C +ATOM 7832 CG PHE B 236 -42.415 -4.254-117.035 1.00 38.00 C +ATOM 7833 CD1 PHE B 236 -42.820 -4.939-118.163 1.00 38.00 C +ATOM 7834 CD2 PHE B 236 -42.264 -4.950-115.852 1.00 38.00 C +ATOM 7835 CE1 PHE B 236 -43.073 -6.291-118.110 1.00 38.00 C +ATOM 7836 CE2 PHE B 236 -42.512 -6.301-115.792 1.00 38.00 C +ATOM 7837 CZ PHE B 236 -42.917 -6.975-116.923 1.00 38.00 C +ATOM 7838 N LYS B 237 -45.411 -2.882-116.049 1.00 38.00 N +ATOM 7839 CA LYS B 237 -46.285 -3.401-115.006 1.00 38.00 C +ATOM 7840 C LYS B 237 -46.411 -4.909-115.181 1.00 38.00 C +ATOM 7841 O LYS B 237 -46.921 -5.359-116.221 1.00 38.00 O +ATOM 7842 CB LYS B 237 -47.660 -2.734-115.082 1.00 39.18 C +ATOM 7843 CG LYS B 237 -47.665 -1.223-114.866 1.00 38.00 C +ATOM 7844 CD LYS B 237 -48.088 -0.849-113.448 1.00 38.00 C +ATOM 7845 CE LYS B 237 -48.228 0.664-113.291 1.00 40.07 C +ATOM 7846 NZ LYS B 237 -49.248 1.242-114.211 1.00 38.00 N +ATOM 7847 N PRO B 238 -45.974 -5.727-114.229 1.00 38.00 N +ATOM 7848 CA PRO B 238 -46.022 -7.181-114.413 1.00 38.00 C +ATOM 7849 C PRO B 238 -47.425 -7.736-114.197 1.00 38.00 C +ATOM 7850 O PRO B 238 -48.317 -7.071-113.673 1.00 39.89 O +ATOM 7851 CB PRO B 238 -45.062 -7.697-113.340 1.00 38.00 C +ATOM 7852 CG PRO B 238 -45.166 -6.693-112.257 1.00 38.00 C +ATOM 7853 CD PRO B 238 -45.364 -5.360-112.940 1.00 38.00 C +ATOM 7854 N MET B 239 -47.597 -8.993-114.603 1.00 38.00 N +ATOM 7855 CA MET B 239 -48.867 -9.677-114.405 1.00 38.00 C +ATOM 7856 C MET B 239 -49.080 -9.987-112.931 1.00 43.70 C +ATOM 7857 O MET B 239 -48.220 -10.587-112.279 1.00 45.25 O +ATOM 7858 CB MET B 239 -48.920 -10.968-115.219 1.00 39.58 C +ATOM 7859 CG MET B 239 -50.220 -11.736-115.023 1.00 45.51 C +ATOM 7860 SD MET B 239 -50.443 -13.179-116.081 1.00 44.00 S +ATOM 7861 CE MET B 239 -49.317 -14.349-115.318 1.00 40.47 C +ATOM 7862 N ARG B 240 -50.251 -9.617-112.418 1.00 44.92 N +ATOM 7863 CA ARG B 240 -50.562 -9.777-111.007 1.00 42.02 C +ATOM 7864 C ARG B 240 -51.809 -10.609-110.757 1.00 38.00 C +ATOM 7865 O ARG B 240 -52.126 -10.877-109.594 1.00 42.42 O +ATOM 7866 CB ARG B 240 -50.728 -8.400-110.347 1.00 47.43 C +ATOM 7867 CG ARG B 240 -49.564 -7.446-110.588 1.00 48.37 C +ATOM 7868 CD ARG B 240 -48.737 -7.270-109.337 1.00 47.74 C +ATOM 7869 NE ARG B 240 -48.774 -8.468-108.507 1.00 51.39 N +ATOM 7870 CZ ARG B 240 -48.082 -8.615-107.383 1.00 64.07 C +ATOM 7871 NH1 ARG B 240 -47.292 -7.635-106.966 1.00 60.02 N +ATOM 7872 NH2 ARG B 240 -48.177 -9.738-106.679 1.00 68.40 N +ATOM 7873 N GLN B 241 -52.521 -11.025-111.801 1.00 38.00 N +ATOM 7874 CA GLN B 241 -53.751 -11.785-111.630 1.00 41.15 C +ATOM 7875 C GLN B 241 -54.073 -12.523-112.919 1.00 41.22 C +ATOM 7876 O GLN B 241 -53.701 -12.082-114.010 1.00 45.67 O +ATOM 7877 CB GLN B 241 -54.928 -10.884-111.243 1.00 45.29 C +ATOM 7878 CG GLN B 241 -55.276 -10.876-109.768 1.00 39.18 C +ATOM 7879 CD GLN B 241 -56.575 -10.154-109.501 1.00 40.77 C +ATOM 7880 OE1 GLN B 241 -56.938 -9.228-110.220 1.00 39.49 O +ATOM 7881 NE2 GLN B 241 -57.297 -10.592-108.482 1.00 51.67 N +ATOM 7882 N GLN B 242 -54.792 -13.635-112.785 1.00 40.45 N +ATOM 7883 CA GLN B 242 -55.223 -14.377-113.959 1.00 49.33 C +ATOM 7884 C GLN B 242 -56.242 -13.561-114.754 1.00 46.51 C +ATOM 7885 O GLN B 242 -56.651 -12.469-114.356 1.00 51.53 O +ATOM 7886 CB GLN B 242 -55.814 -15.729-113.555 1.00 50.49 C +ATOM 7887 CG GLN B 242 -54.820 -16.657-112.889 1.00 46.95 C +ATOM 7888 CD GLN B 242 -53.704 -17.084-113.829 1.00 55.88 C +ATOM 7889 OE1 GLN B 242 -53.895 -17.176-115.043 1.00 62.72 O +ATOM 7890 NE2 GLN B 242 -52.525 -17.326-113.271 1.00 63.12 N +ATOM 7891 N ARG B 243 -56.634 -14.095-115.913 1.00 41.03 N +ATOM 7892 CA ARG B 243 -57.625 -13.410-116.739 1.00 42.48 C +ATOM 7893 C ARG B 243 -59.022 -13.557-116.151 1.00 49.01 C +ATOM 7894 O ARG B 243 -59.784 -12.585-116.078 1.00 49.16 O +ATOM 7895 CB ARG B 243 -57.589 -13.942-118.172 1.00 42.87 C +ATOM 7896 CG ARG B 243 -56.317 -13.621-118.910 1.00 38.00 C +ATOM 7897 CD ARG B 243 -56.020 -12.138-118.850 1.00 38.00 C +ATOM 7898 NE ARG B 243 -54.605 -11.887-119.084 1.00 38.00 N +ATOM 7899 CZ ARG B 243 -54.046 -11.815-120.285 1.00 38.00 C +ATOM 7900 NH1 ARG B 243 -54.783 -11.969-121.373 1.00 38.00 N +ATOM 7901 NH2 ARG B 243 -52.745 -11.592-120.395 1.00 38.81 N +ATOM 7902 N ASP B 244 -59.381 -14.772-115.743 1.00 51.29 N +ATOM 7903 CA ASP B 244 -60.712 -15.052-115.222 1.00 53.43 C +ATOM 7904 C ASP B 244 -60.836 -14.742-113.733 1.00 51.58 C +ATOM 7905 O ASP B 244 -61.683 -15.318-113.051 1.00 55.50 O +ATOM 7906 CB ASP B 244 -61.065 -16.517-115.477 1.00 59.19 C +ATOM 7907 CG ASP B 244 -59.989 -17.468-114.978 1.00 57.82 C +ATOM 7908 OD1 ASP B 244 -59.885 -17.667-113.748 1.00 56.94 O +ATOM 7909 OD2 ASP B 244 -59.245 -18.019-115.821 1.00 54.16 O +ATOM 7910 N GLU B 245 -60.017 -13.819-113.233 1.00 52.70 N +ATOM 7911 CA GLU B 245 -60.009 -13.463-111.821 1.00 53.96 C +ATOM 7912 C GLU B 245 -60.522 -12.043-111.630 1.00 53.80 C +ATOM 7913 O GLU B 245 -60.137 -11.127-112.366 1.00 48.21 O +ATOM 7914 CB GLU B 245 -58.600 -13.582-111.219 1.00 54.20 C +ATOM 7915 CG GLU B 245 -58.179 -15.001-110.833 1.00 63.81 C +ATOM 7916 CD GLU B 245 -56.892 -15.030-110.010 1.00 66.12 C +ATOM 7917 OE1 GLU B 245 -56.328 -13.947-109.744 1.00 59.89 O +ATOM 7918 OE2 GLU B 245 -56.455 -16.133-109.613 1.00 67.31 O +ATOM 7919 N GLU B 246 -61.382 -11.864-110.628 1.00 58.61 N +ATOM 7920 CA GLU B 246 -61.938 -10.563-110.283 1.00 56.29 C +ATOM 7921 C GLU B 246 -61.317 -10.061-108.989 1.00 49.00 C +ATOM 7922 O GLU B 246 -60.745 -10.832-108.214 1.00 51.15 O +ATOM 7923 CB GLU B 246 -63.468 -10.616-110.119 1.00 56.13 C +ATOM 7924 CG GLU B 246 -64.225 -11.318-111.243 1.00 58.04 C +ATOM 7925 CD GLU B 246 -65.738 -11.119-111.168 1.00 59.57 C +ATOM 7926 OE1 GLU B 246 -66.187 -9.987-110.882 1.00 59.29 O +ATOM 7927 OE2 GLU B 246 -66.479 -12.099-111.398 1.00 59.36 O +ATOM 7928 N THR B 247 -61.422 -8.744-108.774 1.00 49.55 N +ATOM 7929 CA THR B 247 -61.138 -8.195-107.456 1.00 53.06 C +ATOM 7930 C THR B 247 -62.168 -8.814-106.528 1.00 58.45 C +ATOM 7931 O THR B 247 -63.375 -8.591-106.700 1.00 54.75 O +ATOM 7932 CB THR B 247 -61.226 -6.667-107.407 1.00 48.05 C +ATOM 7933 OG1 THR B 247 -62.425 -6.281-106.725 1.00 56.91 O +ATOM 7934 CG2 THR B 247 -61.247 -6.080-108.792 1.00 43.40 C +ATOM 7935 N PRO B 248 -61.743 -9.630-105.571 1.00 59.87 N +ATOM 7936 CA PRO B 248 -62.718 -10.321-104.726 1.00 65.10 C +ATOM 7937 C PRO B 248 -63.527 -9.315-103.924 1.00 60.88 C +ATOM 7938 O PRO B 248 -63.047 -8.234-103.579 1.00 54.53 O +ATOM 7939 CB PRO B 248 -61.848 -11.209-103.828 1.00 56.50 C +ATOM 7940 CG PRO B 248 -60.526 -10.521-103.805 1.00 54.81 C +ATOM 7941 CD PRO B 248 -60.355 -9.865-105.136 1.00 49.41 C +ATOM 7942 N VAL B 249 -64.793 -9.659-103.678 1.00 61.78 N +ATOM 7943 CA VAL B 249 -65.597 -8.847-102.781 1.00 58.27 C +ATOM 7944 C VAL B 249 -64.895 -8.791-101.429 1.00 54.11 C +ATOM 7945 O VAL B 249 -64.144 -9.701-101.056 1.00 54.32 O +ATOM 7946 CB VAL B 249 -67.025 -9.404-102.650 1.00 68.03 C +ATOM 7947 CG1 VAL B 249 -67.724 -9.387-104.006 1.00 68.41 C +ATOM 7948 CG2 VAL B 249 -66.996 -10.817-102.069 1.00 57.42 C +ATOM 7949 N ASP B 250 -65.141 -7.707-100.694 1.00 55.39 N +ATOM 7950 CA ASP B 250 -64.452 -7.295 -99.463 1.00 57.08 C +ATOM 7951 C ASP B 250 -63.152 -6.565 -99.775 1.00 56.20 C +ATOM 7952 O ASP B 250 -62.361 -6.308 -98.856 1.00 54.40 O +ATOM 7953 CB ASP B 250 -64.131 -8.440 -98.490 1.00 44.53 C +ATOM 7954 CG ASP B 250 -65.331 -9.324 -98.195 1.00 48.27 C +ATOM 7955 OD1 ASP B 250 -66.464 -8.805 -98.126 1.00 54.88 O +ATOM 7956 OD2 ASP B 250 -65.132 -10.542 -98.006 1.00 45.50 O +ATOM 7957 N PHE B 251 -62.911 -6.197-101.028 1.00 55.48 N +ATOM 7958 CA PHE B 251 -61.694 -5.500-101.418 1.00 49.46 C +ATOM 7959 C PHE B 251 -62.040 -4.051-101.714 1.00 49.76 C +ATOM 7960 O PHE B 251 -62.843 -3.773-102.612 1.00 53.47 O +ATOM 7961 CB PHE B 251 -61.042 -6.161-102.635 1.00 51.50 C +ATOM 7962 CG PHE B 251 -59.821 -6.973-102.306 1.00 46.62 C +ATOM 7963 CD1 PHE B 251 -59.922 -8.142-101.574 1.00 47.34 C +ATOM 7964 CD2 PHE B 251 -58.572 -6.559-102.722 1.00 48.40 C +ATOM 7965 CE1 PHE B 251 -58.798 -8.886-101.271 1.00 40.00 C +ATOM 7966 CE2 PHE B 251 -57.445 -7.296-102.421 1.00 44.69 C +ATOM 7967 CZ PHE B 251 -57.558 -8.462-101.695 1.00 38.53 C +ATOM 7968 N PHE B 252 -61.476 -3.137-100.932 1.00 48.91 N +ATOM 7969 CA PHE B 252 -61.616 -1.724-101.240 1.00 53.47 C +ATOM 7970 C PHE B 252 -60.799 -1.368-102.484 1.00 44.30 C +ATOM 7971 O PHE B 252 -59.952 -2.134-102.952 1.00 40.73 O +ATOM 7972 CB PHE B 252 -61.180 -0.871-100.050 1.00 51.52 C +ATOM 7973 CG PHE B 252 -62.186 -0.813 -98.940 1.00 50.23 C +ATOM 7974 CD1 PHE B 252 -63.257 0.062 -99.009 1.00 55.64 C +ATOM 7975 CD2 PHE B 252 -62.058 -1.624 -97.827 1.00 49.06 C +ATOM 7976 CE1 PHE B 252 -64.189 0.124 -97.988 1.00 58.40 C +ATOM 7977 CE2 PHE B 252 -62.984 -1.569 -96.801 1.00 53.81 C +ATOM 7978 CZ PHE B 252 -64.051 -0.692 -96.880 1.00 61.10 C +ATOM 7979 N TYR B 253 -61.044 -0.166-103.010 1.00 43.15 N +ATOM 7980 CA TYR B 253 -60.341 0.259-104.215 1.00 40.13 C +ATOM 7981 C TYR B 253 -58.848 0.431-103.955 1.00 41.43 C +ATOM 7982 O TYR B 253 -58.022 0.052-104.793 1.00 43.26 O +ATOM 7983 CB TYR B 253 -60.957 1.552-104.762 1.00 38.89 C +ATOM 7984 CG TYR B 253 -61.354 2.545-103.695 1.00 40.72 C +ATOM 7985 CD1 TYR B 253 -62.607 2.486-103.097 1.00 43.67 C +ATOM 7986 CD2 TYR B 253 -60.482 3.543-103.288 1.00 45.39 C +ATOM 7987 CE1 TYR B 253 -62.977 3.386-102.112 1.00 48.14 C +ATOM 7988 CE2 TYR B 253 -60.843 4.453-102.303 1.00 50.50 C +ATOM 7989 CZ TYR B 253 -62.093 4.369-101.717 1.00 51.83 C +ATOM 7990 OH TYR B 253 -62.461 5.273-100.740 1.00 48.36 O +ATOM 7991 N PHE B 254 -58.477 0.959-102.786 1.00 45.00 N +ATOM 7992 CA PHE B 254 -57.075 1.270-102.528 1.00 46.34 C +ATOM 7993 C PHE B 254 -56.213 0.031-102.314 1.00 40.40 C +ATOM 7994 O PHE B 254 -54.983 0.152-102.295 1.00 38.00 O +ATOM 7995 CB PHE B 254 -56.954 2.218-101.328 1.00 48.44 C +ATOM 7996 CG PHE B 254 -57.854 1.868-100.172 1.00 50.88 C +ATOM 7997 CD1 PHE B 254 -57.507 0.865 -99.282 1.00 53.70 C +ATOM 7998 CD2 PHE B 254 -59.044 2.554 -99.968 1.00 49.88 C +ATOM 7999 CE1 PHE B 254 -58.329 0.548 -98.215 1.00 51.06 C +ATOM 8000 CE2 PHE B 254 -59.871 2.238 -98.904 1.00 46.75 C +ATOM 8001 CZ PHE B 254 -59.510 1.237 -98.025 1.00 50.61 C +ATOM 8002 N ILE B 255 -56.811 -1.149-102.178 1.00 40.66 N +ATOM 8003 CA ILE B 255 -56.060 -2.394-102.078 1.00 46.01 C +ATOM 8004 C ILE B 255 -56.277 -3.284-103.298 1.00 42.99 C +ATOM 8005 O ILE B 255 -55.820 -4.434-103.312 1.00 38.00 O +ATOM 8006 CB ILE B 255 -56.390 -3.147-100.777 1.00 45.50 C +ATOM 8007 CG1 ILE B 255 -57.878 -3.513-100.734 1.00 48.29 C +ATOM 8008 CG2 ILE B 255 -55.962 -2.325 -99.564 1.00 41.67 C +ATOM 8009 CD1 ILE B 255 -58.289 -4.362 -99.544 1.00 44.87 C +ATOM 8010 N ASP B 256 -56.956 -2.779-104.329 1.00 40.79 N +ATOM 8011 CA ASP B 256 -57.146 -3.547-105.551 1.00 40.22 C +ATOM 8012 C ASP B 256 -55.799 -3.805-106.219 1.00 39.91 C +ATOM 8013 O ASP B 256 -54.793 -3.149-105.934 1.00 39.55 O +ATOM 8014 CB ASP B 256 -58.092 -2.819-106.512 1.00 44.87 C +ATOM 8015 CG ASP B 256 -58.811 -3.771-107.479 1.00 46.86 C +ATOM 8016 OD1 ASP B 256 -58.492 -4.982-107.490 1.00 46.74 O +ATOM 8017 OD2 ASP B 256 -59.706 -3.308-108.220 1.00 38.28 O +ATOM 8018 N PHE B 257 -55.793 -4.777-107.121 1.00 39.66 N +ATOM 8019 CA PHE B 257 -54.558 -5.247-107.731 1.00 39.64 C +ATOM 8020 C PHE B 257 -54.052 -4.233-108.756 1.00 42.84 C +ATOM 8021 O PHE B 257 -54.496 -3.085-108.826 1.00 48.27 O +ATOM 8022 CB PHE B 257 -54.785 -6.619-108.348 1.00 40.32 C +ATOM 8023 CG PHE B 257 -54.750 -7.731-107.356 1.00 39.27 C +ATOM 8024 CD1 PHE B 257 -53.551 -8.333-107.022 1.00 40.75 C +ATOM 8025 CD2 PHE B 257 -55.910 -8.171-106.747 1.00 39.61 C +ATOM 8026 CE1 PHE B 257 -53.507 -9.359-106.104 1.00 43.97 C +ATOM 8027 CE2 PHE B 257 -55.876 -9.203-105.823 1.00 46.90 C +ATOM 8028 CZ PHE B 257 -54.671 -9.797-105.502 1.00 46.30 C +ATOM 8029 N GLN B 258 -53.106 -4.666-109.574 1.00 40.42 N +ATOM 8030 CA GLN B 258 -52.457 -3.813-110.563 1.00 39.55 C +ATOM 8031 C GLN B 258 -52.313 -4.664-111.826 1.00 45.38 C +ATOM 8032 O GLN B 258 -51.234 -5.171-112.140 1.00 48.33 O +ATOM 8033 CB GLN B 258 -51.110 -3.320-110.052 1.00 49.85 C +ATOM 8034 CG GLN B 258 -50.794 -1.886-110.395 1.00 55.72 C +ATOM 8035 CD GLN B 258 -50.774 -1.000-109.171 1.00 49.68 C +ATOM 8036 OE1 GLN B 258 -51.284 -1.375-108.113 1.00 41.65 O +ATOM 8037 NE2 GLN B 258 -50.171 0.179-109.302 1.00 48.56 N +ATOM 8038 N ARG B 259 -53.416 -4.837-112.550 1.00 43.49 N +ATOM 8039 CA ARG B 259 -53.431 -5.763-113.675 1.00 42.25 C +ATOM 8040 C ARG B 259 -52.771 -5.143-114.901 1.00 43.02 C +ATOM 8041 O ARG B 259 -53.060 -4.000-115.272 1.00 41.21 O +ATOM 8042 CB ARG B 259 -54.857 -6.213-113.994 1.00 38.00 C +ATOM 8043 CG ARG B 259 -55.947 -5.362-113.381 1.00 38.00 C +ATOM 8044 CD ARG B 259 -57.221 -6.163-113.175 1.00 38.00 C +ATOM 8045 NE ARG B 259 -57.434 -6.410-111.758 1.00 38.00 N +ATOM 8046 CZ ARG B 259 -58.052 -5.564-110.943 1.00 41.02 C +ATOM 8047 NH1 ARG B 259 -58.536 -4.421-111.409 1.00 38.00 N +ATOM 8048 NH2 ARG B 259 -58.186 -5.862-109.661 1.00 50.83 N +ATOM 8049 N HIS B 260 -51.874 -5.911-115.524 1.00 40.17 N +ATOM 8050 CA HIS B 260 -51.210 -5.468-116.745 1.00 38.00 C +ATOM 8051 C HIS B 260 -52.189 -5.338-117.902 1.00 38.00 C +ATOM 8052 O HIS B 260 -52.143 -4.356-118.651 1.00 38.00 O +ATOM 8053 CB HIS B 260 -50.096 -6.448-117.109 1.00 38.00 C +ATOM 8054 CG HIS B 260 -50.586 -7.832-117.420 1.00 41.36 C +ATOM 8055 ND1 HIS B 260 -51.535 -8.477-116.656 1.00 44.48 N +ATOM 8056 CD2 HIS B 260 -50.261 -8.692-118.415 1.00 41.96 C +ATOM 8057 CE1 HIS B 260 -51.773 -9.673-117.164 1.00 39.00 C +ATOM 8058 NE2 HIS B 260 -51.012 -9.829-118.231 1.00 40.10 N +ATOM 8059 N ASN B 261 -53.089 -6.308-118.059 1.00 38.00 N +ATOM 8060 CA ASN B 261 -53.999 -6.296-119.195 1.00 38.00 C +ATOM 8061 C ASN B 261 -54.943 -5.103-119.167 1.00 38.00 C +ATOM 8062 O ASN B 261 -55.492 -4.736-120.213 1.00 38.17 O +ATOM 8063 CB ASN B 261 -54.792 -7.597-119.234 1.00 38.00 C +ATOM 8064 CG ASN B 261 -55.645 -7.782-118.013 1.00 38.00 C +ATOM 8065 OD1 ASN B 261 -55.165 -8.204-116.963 1.00 38.74 O +ATOM 8066 ND2 ASN B 261 -56.927 -7.486-118.143 1.00 38.00 N +ATOM 8067 N ALA B 262 -55.145 -4.486-118.005 1.00 38.00 N +ATOM 8068 CA ALA B 262 -56.007 -3.313-117.966 1.00 38.00 C +ATOM 8069 C ALA B 262 -55.312 -2.097-118.553 1.00 38.00 C +ATOM 8070 O ALA B 262 -55.933 -1.325-119.288 1.00 38.00 O +ATOM 8071 CB ALA B 262 -56.445 -3.027-116.531 1.00 38.00 C +ATOM 8072 N GLU B 263 -54.014 -1.940-118.278 1.00 38.00 N +ATOM 8073 CA GLU B 263 -53.258 -0.832-118.858 1.00 38.46 C +ATOM 8074 C GLU B 263 -53.256 -0.899-120.378 1.00 39.52 C +ATOM 8075 O GLU B 263 -53.267 0.135-121.055 1.00 39.13 O +ATOM 8076 CB GLU B 263 -51.825 -0.832-118.333 1.00 41.82 C +ATOM 8077 CG GLU B 263 -51.682 -0.387-116.895 1.00 46.50 C +ATOM 8078 CD GLU B 263 -51.659 1.124-116.754 1.00 54.60 C +ATOM 8079 OE1 GLU B 263 -51.195 1.803-117.698 1.00 58.16 O +ATOM 8080 OE2 GLU B 263 -52.090 1.631-115.695 1.00 54.30 O +ATOM 8081 N ILE B 264 -53.228 -2.109-120.931 1.00 38.00 N +ATOM 8082 CA ILE B 264 -53.304 -2.264-122.378 1.00 38.00 C +ATOM 8083 C ILE B 264 -54.700 -1.915-122.869 1.00 40.13 C +ATOM 8084 O ILE B 264 -54.883 -1.005-123.686 1.00 39.24 O +ATOM 8085 CB ILE B 264 -52.913 -3.693-122.782 1.00 38.00 C +ATOM 8086 CG1 ILE B 264 -51.606 -4.081-122.104 1.00 38.00 C +ATOM 8087 CG2 ILE B 264 -52.800 -3.799-124.280 1.00 45.02 C +ATOM 8088 CD1 ILE B 264 -51.260 -5.530-122.264 1.00 39.44 C +ATOM 8089 N ALA B 265 -55.711 -2.612-122.344 1.00 43.29 N +ATOM 8090 CA ALA B 265 -57.077 -2.397-122.805 1.00 40.46 C +ATOM 8091 C ALA B 265 -57.517 -0.955-122.602 1.00 38.00 C +ATOM 8092 O ALA B 265 -58.326 -0.439-123.380 1.00 38.00 O +ATOM 8093 CB ALA B 265 -58.029 -3.352-122.087 1.00 38.00 C +ATOM 8094 N ALA B 266 -56.996 -0.287-121.571 1.00 38.00 N +ATOM 8095 CA ALA B 266 -57.303 1.125-121.392 1.00 38.00 C +ATOM 8096 C ALA B 266 -56.760 1.960-122.536 1.00 38.00 C +ATOM 8097 O ALA B 266 -57.332 3.003-122.869 1.00 38.94 O +ATOM 8098 CB ALA B 266 -56.742 1.631-120.068 1.00 38.00 C +ATOM 8099 N PHE B 267 -55.654 1.534-123.145 1.00 38.00 N +ATOM 8100 CA PHE B 267 -55.128 2.284-124.277 1.00 38.00 C +ATOM 8101 C PHE B 267 -55.998 2.096-125.511 1.00 39.40 C +ATOM 8102 O PHE B 267 -56.314 3.064-126.213 1.00 42.73 O +ATOM 8103 CB PHE B 267 -53.689 1.881-124.565 1.00 38.00 C +ATOM 8104 CG PHE B 267 -53.192 2.371-125.884 1.00 38.00 C +ATOM 8105 CD1 PHE B 267 -53.173 3.726-126.170 1.00 38.00 C +ATOM 8106 CD2 PHE B 267 -52.760 1.480-126.845 1.00 38.00 C +ATOM 8107 CE1 PHE B 267 -52.723 4.183-127.390 1.00 38.00 C +ATOM 8108 CE2 PHE B 267 -52.308 1.930-128.064 1.00 39.72 C +ATOM 8109 CZ PHE B 267 -52.288 3.285-128.338 1.00 38.00 C +ATOM 8110 N HIS B 268 -56.387 0.855-125.801 1.00 39.17 N +ATOM 8111 CA HIS B 268 -57.223 0.606-126.969 1.00 38.00 C +ATOM 8112 C HIS B 268 -58.571 1.300-126.841 1.00 38.00 C +ATOM 8113 O HIS B 268 -59.087 1.849-127.820 1.00 50.69 O +ATOM 8114 CB HIS B 268 -57.393 -0.896-127.169 1.00 38.23 C +ATOM 8115 CG HIS B 268 -56.120 -1.587-127.536 1.00 40.69 C +ATOM 8116 ND1 HIS B 268 -55.877 -2.078-128.800 1.00 46.33 N +ATOM 8117 CD2 HIS B 268 -55.001 -1.832-126.815 1.00 44.31 C +ATOM 8118 CE1 HIS B 268 -54.669 -2.614-128.835 1.00 54.35 C +ATOM 8119 NE2 HIS B 268 -54.115 -2.474-127.644 1.00 49.44 N +ATOM 8120 N LEU B 269 -59.153 1.301-125.640 1.00 38.00 N +ATOM 8121 CA LEU B 269 -60.387 2.051-125.428 1.00 38.00 C +ATOM 8122 C LEU B 269 -60.160 3.543-125.624 1.00 38.00 C +ATOM 8123 O LEU B 269 -61.038 4.249-126.129 1.00 38.00 O +ATOM 8124 CB LEU B 269 -60.940 1.775-124.037 1.00 38.96 C +ATOM 8125 CG LEU B 269 -62.443 1.542-123.916 1.00 38.00 C +ATOM 8126 CD1 LEU B 269 -62.837 1.754-122.476 1.00 48.19 C +ATOM 8127 CD2 LEU B 269 -63.250 2.443-124.822 1.00 38.00 C +ATOM 8128 N ASP B 270 -58.996 4.046-125.205 1.00 38.00 N +ATOM 8129 CA ASP B 270 -58.652 5.431-125.499 1.00 38.00 C +ATOM 8130 C ASP B 270 -58.582 5.656-127.002 1.00 38.00 C +ATOM 8131 O ASP B 270 -59.047 6.684-127.508 1.00 40.56 O +ATOM 8132 CB ASP B 270 -57.324 5.799-124.835 1.00 38.00 C +ATOM 8133 CG ASP B 270 -56.906 7.234-125.105 1.00 38.00 C +ATOM 8134 OD1 ASP B 270 -57.748 8.045-125.524 1.00 38.00 O +ATOM 8135 OD2 ASP B 270 -55.720 7.554-124.908 1.00 38.00 O +ATOM 8136 N ARG B 271 -58.014 4.698-127.734 1.00 38.00 N +ATOM 8137 CA ARG B 271 -57.901 4.857-129.177 1.00 38.00 C +ATOM 8138 C ARG B 271 -59.260 4.736-129.854 1.00 38.00 C +ATOM 8139 O ARG B 271 -59.562 5.491-130.785 1.00 42.66 O +ATOM 8140 CB ARG B 271 -56.914 3.833-129.735 1.00 38.00 C +ATOM 8141 CG ARG B 271 -56.421 4.175-131.115 1.00 38.00 C +ATOM 8142 CD ARG B 271 -55.170 3.403-131.508 1.00 38.77 C +ATOM 8143 NE ARG B 271 -55.232 1.977-131.206 1.00 43.99 N +ATOM 8144 CZ ARG B 271 -54.194 1.156-131.332 1.00 39.29 C +ATOM 8145 NH1 ARG B 271 -53.030 1.632-131.750 1.00 38.00 N +ATOM 8146 NH2 ARG B 271 -54.312 -0.133-131.038 1.00 38.00 N +ATOM 8147 N ILE B 272 -60.108 3.827-129.368 1.00 38.02 N +ATOM 8148 CA ILE B 272 -61.415 3.602-129.981 1.00 38.00 C +ATOM 8149 C ILE B 272 -62.344 4.787-129.726 1.00 38.00 C +ATOM 8150 O ILE B 272 -63.143 5.164-130.591 1.00 38.00 O +ATOM 8151 CB ILE B 272 -62.018 2.277-129.470 1.00 38.00 C +ATOM 8152 CG1 ILE B 272 -61.671 1.112-130.400 1.00 38.00 C +ATOM 8153 CG2 ILE B 272 -63.519 2.369-129.370 1.00 41.88 C +ATOM 8154 CD1 ILE B 272 -60.211 0.767-130.457 1.00 38.00 C +ATOM 8155 N LEU B 273 -62.269 5.386-128.537 1.00 38.00 N +ATOM 8156 CA LEU B 273 -63.120 6.535-128.246 1.00 38.15 C +ATOM 8157 C LEU B 273 -62.663 7.802-128.953 1.00 38.00 C +ATOM 8158 O LEU B 273 -63.414 8.782-128.969 1.00 38.00 O +ATOM 8159 CB LEU B 273 -63.169 6.798-126.736 1.00 45.54 C +ATOM 8160 CG LEU B 273 -63.913 5.840-125.802 1.00 38.00 C +ATOM 8161 CD1 LEU B 273 -63.697 6.242-124.364 1.00 38.00 C +ATOM 8162 CD2 LEU B 273 -65.390 5.806-126.111 1.00 38.00 C +ATOM 8163 N ASP B 274 -61.473 7.796-129.553 1.00 39.56 N +ATOM 8164 CA ASP B 274 -60.839 9.005-130.087 1.00 50.96 C +ATOM 8165 C ASP B 274 -60.647 10.066-129.007 1.00 45.72 C +ATOM 8166 O ASP B 274 -60.666 11.267-129.289 1.00 50.77 O +ATOM 8167 CB ASP B 274 -61.620 9.588-131.273 1.00 56.99 C +ATOM 8168 CG ASP B 274 -60.792 10.576-132.096 1.00 63.58 C +ATOM 8169 OD1 ASP B 274 -59.634 10.245-132.433 1.00 64.14 O +ATOM 8170 OD2 ASP B 274 -61.299 11.680-132.401 1.00 61.01 O +ATOM 8171 N PHE B 275 -60.449 9.639-127.761 1.00 40.75 N +ATOM 8172 CA PHE B 275 -60.016 10.586-126.742 1.00 46.89 C +ATOM 8173 C PHE B 275 -58.553 10.950-126.943 1.00 47.40 C +ATOM 8174 O PHE B 275 -58.183 12.129-126.864 1.00 43.47 O +ATOM 8175 CB PHE B 275 -60.231 10.002-125.346 1.00 49.33 C +ATOM 8176 CG PHE B 275 -61.629 10.151-124.829 1.00 45.49 C +ATOM 8177 CD1 PHE B 275 -62.508 11.040-125.413 1.00 49.45 C +ATOM 8178 CD2 PHE B 275 -62.072 9.369-123.779 1.00 43.61 C +ATOM 8179 CE1 PHE B 275 -63.797 11.164-124.939 1.00 51.91 C +ATOM 8180 CE2 PHE B 275 -63.355 9.485-123.303 1.00 42.27 C +ATOM 8181 CZ PHE B 275 -64.222 10.384-123.884 1.00 48.57 C +ATOM 8182 N ARG B 276 -57.714 9.948-127.218 1.00 46.45 N +ATOM 8183 CA ARG B 276 -56.297 10.144-127.515 1.00 42.54 C +ATOM 8184 C ARG B 276 -55.599 10.850-126.353 1.00 44.44 C +ATOM 8185 O ARG B 276 -55.121 11.980-126.469 1.00 49.01 O +ATOM 8186 CB ARG B 276 -56.117 10.909-128.835 1.00 49.45 C +ATOM 8187 CG ARG B 276 -55.775 10.026-130.036 1.00 49.32 C +ATOM 8188 CD ARG B 276 -56.268 10.596-131.368 1.00 43.60 C +ATOM 8189 NE ARG B 276 -55.911 11.998-131.557 1.00 44.06 N +ATOM 8190 CZ ARG B 276 -56.789 12.996-131.544 1.00 52.83 C +ATOM 8191 NH1 ARG B 276 -58.077 12.738-131.357 1.00 55.82 N +ATOM 8192 NH2 ARG B 276 -56.382 14.247-131.723 1.00 54.03 N +ATOM 8193 N ARG B 277 -55.590 10.176-125.200 1.00 43.54 N +ATOM 8194 CA ARG B 277 -55.070 10.791-123.980 1.00 40.76 C +ATOM 8195 C ARG B 277 -54.206 9.875-123.125 1.00 43.35 C +ATOM 8196 O ARG B 277 -53.369 10.391-122.380 1.00 45.74 O +ATOM 8197 CB ARG B 277 -56.222 11.332-123.129 1.00 39.25 C +ATOM 8198 CG ARG B 277 -56.905 12.507-123.778 1.00 44.09 C +ATOM 8199 CD ARG B 277 -58.207 12.854-123.117 1.00 46.06 C +ATOM 8200 NE ARG B 277 -59.129 13.412-124.100 1.00 51.70 N +ATOM 8201 CZ ARG B 277 -60.296 13.962-123.795 1.00 61.72 C +ATOM 8202 NH1 ARG B 277 -60.676 14.029-122.526 1.00 76.96 N +ATOM 8203 NH2 ARG B 277 -61.076 14.447-124.754 1.00 49.42 N +ATOM 8204 N VAL B 278 -54.356 8.555-123.198 1.00 44.95 N +ATOM 8205 CA VAL B 278 -53.499 7.658-122.425 1.00 39.78 C +ATOM 8206 C VAL B 278 -52.287 7.306-123.280 1.00 38.00 C +ATOM 8207 O VAL B 278 -52.382 7.295-124.516 1.00 38.00 O +ATOM 8208 CB VAL B 278 -54.259 6.399-121.969 1.00 38.00 C +ATOM 8209 CG1 VAL B 278 -55.739 6.692-121.809 1.00 38.00 C +ATOM 8210 CG2 VAL B 278 -54.038 5.256-122.925 1.00 38.00 C +ATOM 8211 N PRO B 279 -51.130 7.031-122.677 1.00 38.00 N +ATOM 8212 CA PRO B 279 -49.960 6.697-123.482 1.00 38.00 C +ATOM 8213 C PRO B 279 -50.106 5.327-124.097 1.00 38.00 C +ATOM 8214 O PRO B 279 -50.763 4.434-123.527 1.00 38.82 O +ATOM 8215 CB PRO B 279 -48.808 6.738-122.459 1.00 42.73 C +ATOM 8216 CG PRO B 279 -49.345 7.519-121.297 1.00 38.00 C +ATOM 8217 CD PRO B 279 -50.794 7.185-121.254 1.00 38.00 C +ATOM 8218 N PRO B 280 -49.527 5.096-125.280 1.00 38.00 N +ATOM 8219 CA PRO B 280 -49.623 3.779-125.919 1.00 40.05 C +ATOM 8220 C PRO B 280 -49.064 2.670-125.040 1.00 38.00 C +ATOM 8221 O PRO B 280 -48.071 2.848-124.332 1.00 38.00 O +ATOM 8222 CB PRO B 280 -48.809 3.946-127.206 1.00 38.00 C +ATOM 8223 CG PRO B 280 -48.852 5.406-127.481 1.00 39.66 C +ATOM 8224 CD PRO B 280 -48.838 6.076-126.136 1.00 38.00 C +ATOM 8225 N THR B 281 -49.726 1.518-125.080 1.00 38.00 N +ATOM 8226 CA THR B 281 -49.369 0.411-124.210 1.00 38.00 C +ATOM 8227 C THR B 281 -49.472 -0.901-124.969 1.00 38.00 C +ATOM 8228 O THR B 281 -50.481 -1.167-125.629 1.00 38.00 O +ATOM 8229 CB THR B 281 -50.274 0.392-122.979 1.00 38.00 C +ATOM 8230 OG1 THR B 281 -50.187 1.657-122.315 1.00 38.00 O +ATOM 8231 CG2 THR B 281 -49.848 -0.697-122.024 1.00 38.69 C +ATOM 8232 N VAL B 282 -48.422 -1.712-124.873 1.00 40.79 N +ATOM 8233 CA VAL B 282 -48.383 -3.022-125.500 1.00 39.81 C +ATOM 8234 C VAL B 282 -48.105 -4.053-124.417 1.00 40.58 C +ATOM 8235 O VAL B 282 -47.577 -3.748-123.345 1.00 38.00 O +ATOM 8236 CB VAL B 282 -47.333 -3.102-126.637 1.00 38.00 C +ATOM 8237 CG1 VAL B 282 -46.804 -1.730-126.955 1.00 38.00 C +ATOM 8238 CG2 VAL B 282 -46.179 -4.026-126.290 1.00 38.00 C +ATOM 8239 N GLY B 283 -48.487 -5.287-124.705 1.00 47.08 N +ATOM 8240 CA GLY B 283 -48.130 -6.415-123.876 1.00 42.02 C +ATOM 8241 C GLY B 283 -46.906 -7.112-124.437 1.00 42.67 C +ATOM 8242 O GLY B 283 -46.687 -7.139-125.645 1.00 48.54 O +ATOM 8243 N ARG B 284 -46.091 -7.652-123.541 1.00 38.00 N +ATOM 8244 CA ARG B 284 -44.861 -8.299-123.955 1.00 38.00 C +ATOM 8245 C ARG B 284 -44.470 -9.336-122.924 1.00 38.00 C +ATOM 8246 O ARG B 284 -44.570 -9.093-121.721 1.00 38.00 O +ATOM 8247 CB ARG B 284 -43.739 -7.283-124.126 1.00 38.00 C +ATOM 8248 CG ARG B 284 -42.373 -7.894-124.233 1.00 38.00 C +ATOM 8249 CD ARG B 284 -41.393 -6.833-124.587 1.00 38.00 C +ATOM 8250 NE ARG B 284 -40.042 -7.353-124.687 1.00 38.00 N +ATOM 8251 CZ ARG B 284 -39.005 -6.610-125.043 1.00 38.00 C +ATOM 8252 NH1 ARG B 284 -39.187 -5.329-125.333 1.00 38.00 N +ATOM 8253 NH2 ARG B 284 -37.792 -7.141-125.112 1.00 43.45 N +ATOM 8254 N ILE B 285 -44.002 -10.474-123.403 1.00 40.74 N +ATOM 8255 CA ILE B 285 -43.453 -11.505-122.539 1.00 38.00 C +ATOM 8256 C ILE B 285 -41.986 -11.175-122.301 1.00 40.97 C +ATOM 8257 O ILE B 285 -41.238 -10.905-123.250 1.00 39.37 O +ATOM 8258 CB ILE B 285 -43.626 -12.892-123.170 1.00 38.00 C +ATOM 8259 CG1 ILE B 285 -45.104 -13.140-123.468 1.00 38.00 C +ATOM 8260 CG2 ILE B 285 -43.070 -13.959-122.251 1.00 38.00 C +ATOM 8261 CD1 ILE B 285 -45.372 -14.455-124.133 1.00 38.69 C +ATOM 8262 N VAL B 286 -41.582 -11.152-121.033 1.00 39.53 N +ATOM 8263 CA VAL B 286 -40.262 -10.677-120.631 1.00 45.39 C +ATOM 8264 C VAL B 286 -39.486 -11.827-119.995 1.00 42.84 C +ATOM 8265 O VAL B 286 -40.030 -12.561-119.164 1.00 48.08 O +ATOM 8266 CB VAL B 286 -40.374 -9.489-119.657 1.00 40.99 C +ATOM 8267 CG1 VAL B 286 -38.998 -8.943-119.313 1.00 38.85 C +ATOM 8268 CG2 VAL B 286 -41.257 -8.394-120.240 1.00 38.00 C +ATOM 8269 N ASN B 287 -38.225 -11.997-120.401 1.00 38.85 N +ATOM 8270 CA ASN B 287 -37.289 -12.872-119.690 1.00 38.51 C +ATOM 8271 C ASN B 287 -36.754 -12.046-118.529 1.00 38.00 C +ATOM 8272 O ASN B 287 -35.854 -11.221-118.702 1.00 40.99 O +ATOM 8273 CB ASN B 287 -36.173 -13.364-120.616 1.00 49.65 C +ATOM 8274 CG ASN B 287 -35.305 -14.486-119.997 1.00 50.85 C +ATOM 8275 OD1 ASN B 287 -35.142 -14.560-118.781 1.00 54.06 O +ATOM 8276 ND2 ASN B 287 -34.745 -15.355-120.850 1.00 38.00 N +ATOM 8277 N VAL B 288 -37.347 -12.237-117.347 1.00 38.00 N +ATOM 8278 CA VAL B 288 -37.039 -11.399-116.194 1.00 38.00 C +ATOM 8279 C VAL B 288 -35.581 -11.504-115.786 1.00 38.00 C +ATOM 8280 O VAL B 288 -35.053 -10.594-115.140 1.00 38.00 O +ATOM 8281 CB VAL B 288 -37.965 -11.757-115.019 1.00 38.00 C +ATOM 8282 CG1 VAL B 288 -39.389 -11.369-115.344 1.00 38.00 C +ATOM 8283 CG2 VAL B 288 -37.877 -13.235-114.721 1.00 38.00 C +ATOM 8284 N THR B 289 -34.910 -12.594-116.145 1.00 38.00 N +ATOM 8285 CA THR B 289 -33.485 -12.688-115.868 1.00 38.00 C +ATOM 8286 C THR B 289 -32.679 -11.914-116.907 1.00 40.36 C +ATOM 8287 O THR B 289 -31.817 -11.103-116.555 1.00 40.21 O +ATOM 8288 CB THR B 289 -33.043 -14.150-115.825 1.00 38.00 C +ATOM 8289 OG1 THR B 289 -33.775 -14.842-114.808 1.00 38.00 O +ATOM 8290 CG2 THR B 289 -31.564 -14.230-115.500 1.00 46.15 C +ATOM 8291 N LYS B 290 -32.935 -12.168-118.193 1.00 42.88 N +ATOM 8292 CA LYS B 290 -32.147 -11.552-119.256 1.00 44.04 C +ATOM 8293 C LYS B 290 -32.518 -10.095-119.502 1.00 38.00 C +ATOM 8294 O LYS B 290 -31.649 -9.295-119.863 1.00 38.00 O +ATOM 8295 CB LYS B 290 -32.315 -12.350-120.553 1.00 49.07 C +ATOM 8296 CG LYS B 290 -31.464 -11.860-121.729 1.00 49.35 C +ATOM 8297 CD LYS B 290 -31.772 -12.633-123.013 1.00 53.34 C +ATOM 8298 CE LYS B 290 -33.136 -12.247-123.582 1.00 52.38 C +ATOM 8299 NZ LYS B 290 -33.605 -13.139-124.685 1.00 41.24 N +ATOM 8300 N GLU B 291 -33.776 -9.722-119.293 1.00 38.00 N +ATOM 8301 CA GLU B 291 -34.247 -8.402-119.685 1.00 38.34 C +ATOM 8302 C GLU B 291 -34.504 -7.463-118.517 1.00 38.00 C +ATOM 8303 O GLU B 291 -34.836 -6.295-118.748 1.00 38.00 O +ATOM 8304 CB GLU B 291 -35.515 -8.527-120.539 1.00 42.31 C +ATOM 8305 CG GLU B 291 -35.230 -8.824-122.002 1.00 45.53 C +ATOM 8306 CD GLU B 291 -36.436 -9.356-122.746 1.00 41.97 C +ATOM 8307 OE1 GLU B 291 -37.425 -9.745-122.093 1.00 38.00 O +ATOM 8308 OE2 GLU B 291 -36.397 -9.375-123.991 1.00 48.95 O +ATOM 8309 N ILE B 292 -34.345 -7.923-117.277 1.00 38.00 N +ATOM 8310 CA ILE B 292 -34.515 -7.056-116.115 1.00 38.00 C +ATOM 8311 C ILE B 292 -33.296 -7.156-115.209 1.00 38.00 C +ATOM 8312 O ILE B 292 -32.565 -6.178-115.023 1.00 38.00 O +ATOM 8313 CB ILE B 292 -35.796 -7.408-115.336 1.00 38.00 C +ATOM 8314 CG1 ILE B 292 -37.041 -7.170-116.195 1.00 38.00 C +ATOM 8315 CG2 ILE B 292 -35.867 -6.598-114.058 1.00 38.00 C +ATOM 8316 CD1 ILE B 292 -38.345 -7.528-115.500 1.00 38.00 C +ATOM 8317 N LEU B 293 -33.041 -8.349-114.674 1.00 38.00 N +ATOM 8318 CA LEU B 293 -31.984 -8.497-113.681 1.00 38.00 C +ATOM 8319 C LEU B 293 -30.609 -8.256-114.291 1.00 38.00 C +ATOM 8320 O LEU B 293 -29.782 -7.539-113.719 1.00 38.00 O +ATOM 8321 CB LEU B 293 -32.055 -9.883-113.050 1.00 38.00 C +ATOM 8322 CG LEU B 293 -30.897 -10.198-112.111 1.00 38.00 C +ATOM 8323 CD1 LEU B 293 -30.833 -9.193-110.983 1.00 38.00 C +ATOM 8324 CD2 LEU B 293 -31.051 -11.601-111.575 1.00 46.77 C +ATOM 8325 N GLU B 294 -30.342 -8.850-115.447 1.00 38.00 N +ATOM 8326 CA GLU B 294 -29.023 -8.749-116.057 1.00 38.88 C +ATOM 8327 C GLU B 294 -28.767 -7.400-116.722 1.00 38.00 C +ATOM 8328 O GLU B 294 -27.683 -7.200-117.281 1.00 38.00 O +ATOM 8329 CB GLU B 294 -28.836 -9.888-117.063 1.00 42.19 C +ATOM 8330 CG GLU B 294 -28.690 -11.254-116.403 1.00 42.97 C +ATOM 8331 CD GLU B 294 -28.446 -12.368-117.402 1.00 54.79 C +ATOM 8332 OE1 GLU B 294 -28.102 -12.066-118.565 1.00 55.94 O +ATOM 8333 OE2 GLU B 294 -28.602 -13.549-117.023 1.00 60.15 O +ATOM 8334 N VAL B 295 -29.718 -6.469-116.672 1.00 38.00 N +ATOM 8335 CA VAL B 295 -29.535 -5.144-117.246 1.00 38.00 C +ATOM 8336 C VAL B 295 -29.671 -4.031-116.218 1.00 41.89 C +ATOM 8337 O VAL B 295 -29.543 -2.857-116.579 1.00 43.34 O +ATOM 8338 CB VAL B 295 -30.489 -4.896-118.433 1.00 38.00 C +ATOM 8339 CG1 VAL B 295 -29.735 -5.046-119.737 1.00 42.07 C +ATOM 8340 CG2 VAL B 295 -31.643 -5.854-118.393 1.00 38.00 C +ATOM 8341 N THR B 296 -29.968 -4.352-114.960 1.00 45.50 N +ATOM 8342 CA THR B 296 -30.092 -3.333-113.923 1.00 43.84 C +ATOM 8343 C THR B 296 -28.755 -3.053-113.239 1.00 46.48 C +ATOM 8344 O THR B 296 -28.033 -3.970-112.835 1.00 45.03 O +ATOM 8345 CB THR B 296 -31.129 -3.739-112.875 1.00 38.00 C +ATOM 8346 OG1 THR B 296 -31.210 -2.716-111.884 1.00 44.48 O +ATOM 8347 CG2 THR B 296 -30.741 -5.036-112.200 1.00 38.00 C +ATOM 8348 N LYS B 297 -28.455 -1.769-113.071 1.00 51.20 N +ATOM 8349 CA LYS B 297 -27.283 -1.328-112.333 1.00 56.95 C +ATOM 8350 C LYS B 297 -27.623 -1.016-110.884 1.00 57.57 C +ATOM 8351 O LYS B 297 -26.733 -0.652-110.108 1.00 62.41 O +ATOM 8352 CB LYS B 297 -26.680 -0.087-113.006 1.00 67.81 C +ATOM 8353 CG LYS B 297 -26.278 -0.291-114.468 1.00 72.59 C +ATOM 8354 CD LYS B 297 -25.744 0.998-115.101 1.00 79.67 C +ATOM 8355 CE LYS B 297 -25.514 0.864-116.614 1.00 77.24 C +ATOM 8356 NZ LYS B 297 -26.770 0.739-117.414 1.00 55.82 N +ATOM 8357 N ASN B 298 -28.891 -1.168-110.510 1.00 61.76 N +ATOM 8358 CA ASN B 298 -29.370 -0.825-109.178 1.00 56.90 C +ATOM 8359 C ASN B 298 -29.128 -1.978-108.212 1.00 47.16 C +ATOM 8360 O ASN B 298 -29.655 -3.081-108.404 1.00 40.59 O +ATOM 8361 CB ASN B 298 -30.855 -0.484-109.241 1.00 51.76 C +ATOM 8362 CG ASN B 298 -31.376 0.044-107.943 1.00 41.36 C +ATOM 8363 OD1 ASN B 298 -31.600 -0.722-107.016 1.00 42.72 O +ATOM 8364 ND2 ASN B 298 -31.598 1.350-107.867 1.00 41.82 N +ATOM 8365 N GLU B 299 -28.371 -1.702-107.145 1.00 44.57 N +ATOM 8366 CA GLU B 299 -27.988 -2.755-106.211 1.00 47.32 C +ATOM 8367 C GLU B 299 -29.187 -3.296-105.437 1.00 48.13 C +ATOM 8368 O GLU B 299 -29.172 -4.458-105.013 1.00 53.59 O +ATOM 8369 CB GLU B 299 -26.910 -2.242-105.247 1.00 46.04 C +ATOM 8370 CG GLU B 299 -25.787 -1.427-105.902 1.00 49.87 C +ATOM 8371 CD GLU B 299 -24.492 -2.219-106.036 1.00 55.89 C +ATOM 8372 OE1 GLU B 299 -24.576 -3.427-106.334 1.00 61.83 O +ATOM 8373 OE2 GLU B 299 -23.394 -1.642-105.871 1.00 62.10 O +ATOM 8374 N ILE B 300 -30.231 -2.486-105.244 1.00 43.80 N +ATOM 8375 CA ILE B 300 -31.426 -2.988-104.572 1.00 40.41 C +ATOM 8376 C ILE B 300 -32.190 -3.936-105.477 1.00 41.21 C +ATOM 8377 O ILE B 300 -32.688 -4.975-105.030 1.00 42.46 O +ATOM 8378 CB ILE B 300 -32.324 -1.835-104.105 1.00 38.00 C +ATOM 8379 CG1 ILE B 300 -31.480 -0.730-103.486 1.00 38.00 C +ATOM 8380 CG2 ILE B 300 -33.386 -2.349-103.150 1.00 38.00 C +ATOM 8381 CD1 ILE B 300 -32.286 0.453-103.077 1.00 38.00 C +ATOM 8382 N LEU B 301 -32.340 -3.571-106.751 1.00 41.89 N +ATOM 8383 CA LEU B 301 -33.103 -4.418-107.655 1.00 42.24 C +ATOM 8384 C LEU B 301 -32.460 -5.789-107.796 1.00 42.99 C +ATOM 8385 O LEU B 301 -33.169 -6.795-107.890 1.00 45.86 O +ATOM 8386 CB LEU B 301 -33.246 -3.742-109.019 1.00 38.84 C +ATOM 8387 CG LEU B 301 -34.322 -4.353-109.916 1.00 38.00 C +ATOM 8388 CD1 LEU B 301 -35.629 -4.460-109.161 1.00 38.00 C +ATOM 8389 CD2 LEU B 301 -34.509 -3.531-111.176 1.00 38.00 C +ATOM 8390 N GLN B 302 -31.128 -5.863-107.744 1.00 40.49 N +ATOM 8391 CA GLN B 302 -30.479 -7.167-107.789 1.00 42.40 C +ATOM 8392 C GLN B 302 -30.761 -7.996-106.543 1.00 43.67 C +ATOM 8393 O GLN B 302 -30.693 -9.229-106.610 1.00 44.98 O +ATOM 8394 CB GLN B 302 -28.967 -7.006-107.986 1.00 41.28 C +ATOM 8395 CG GLN B 302 -28.594 -6.315-109.285 1.00 47.39 C +ATOM 8396 CD GLN B 302 -27.126 -5.954-109.368 1.00 53.90 C +ATOM 8397 OE1 GLN B 302 -26.627 -5.147-108.586 1.00 49.97 O +ATOM 8398 NE2 GLN B 302 -26.428 -6.538-110.336 1.00 63.34 N +ATOM 8399 N SER B 303 -31.085 -7.353-105.418 1.00 47.23 N +ATOM 8400 CA SER B 303 -31.288 -8.065-104.159 1.00 53.16 C +ATOM 8401 C SER B 303 -32.684 -8.669-104.021 1.00 49.11 C +ATOM 8402 O SER B 303 -32.868 -9.581-103.204 1.00 47.30 O +ATOM 8403 CB SER B 303 -31.001 -7.129-102.972 1.00 48.75 C +ATOM 8404 OG SER B 303 -32.087 -6.254-102.711 1.00 39.63 O +ATOM 8405 N VAL B 304 -33.653 -8.207-104.802 1.00 45.45 N +ATOM 8406 CA VAL B 304 -35.031 -8.657-104.648 1.00 45.57 C +ATOM 8407 C VAL B 304 -35.333 -9.812-105.600 1.00 48.97 C +ATOM 8408 O VAL B 304 -36.481 -10.249-105.717 1.00 46.69 O +ATOM 8409 CB VAL B 304 -36.011 -7.493-104.860 1.00 40.17 C +ATOM 8410 CG1 VAL B 304 -35.685 -6.369-103.916 1.00 45.10 C +ATOM 8411 CG2 VAL B 304 -35.961 -7.025-106.294 1.00 45.42 C +ATOM 8412 N PHE B 305 -34.314 -10.303-106.299 1.00 45.79 N +ATOM 8413 CA PHE B 305 -34.471 -11.462-107.166 1.00 42.05 C +ATOM 8414 C PHE B 305 -34.026 -12.720-106.439 1.00 44.90 C +ATOM 8415 O PHE B 305 -32.901 -12.785-105.932 1.00 46.42 O +ATOM 8416 CB PHE B 305 -33.679 -11.296-108.459 1.00 38.80 C +ATOM 8417 CG PHE B 305 -34.396 -10.508-109.490 1.00 38.00 C +ATOM 8418 CD1 PHE B 305 -34.270 -9.138-109.540 1.00 38.00 C +ATOM 8419 CD2 PHE B 305 -35.229 -11.137-110.389 1.00 38.00 C +ATOM 8420 CE1 PHE B 305 -34.940 -8.408-110.489 1.00 38.00 C +ATOM 8421 CE2 PHE B 305 -35.902 -10.420-111.337 1.00 41.30 C +ATOM 8422 CZ PHE B 305 -35.760 -9.051-111.392 1.00 42.76 C +ATOM 8423 N PHE B 306 -34.911 -13.714-106.387 1.00 43.35 N +ATOM 8424 CA PHE B 306 -34.613 -14.982-105.740 1.00 48.95 C +ATOM 8425 C PHE B 306 -35.162 -16.123-106.589 1.00 48.03 C +ATOM 8426 O PHE B 306 -35.726 -15.912-107.667 1.00 43.10 O +ATOM 8427 CB PHE B 306 -35.191 -15.023-104.322 1.00 56.10 C +ATOM 8428 CG PHE B 306 -36.688 -14.968-104.280 1.00 51.44 C +ATOM 8429 CD1 PHE B 306 -37.346 -13.755-104.266 1.00 50.80 C +ATOM 8430 CD2 PHE B 306 -37.435 -16.132-104.238 1.00 49.76 C +ATOM 8431 CE1 PHE B 306 -38.724 -13.705-104.222 1.00 54.14 C +ATOM 8432 CE2 PHE B 306 -38.809 -16.089-104.194 1.00 46.58 C +ATOM 8433 CZ PHE B 306 -39.457 -14.873-104.186 1.00 49.12 C +ATOM 8434 N VAL B 307 -35.031 -17.341-106.070 1.00 48.90 N +ATOM 8435 CA VAL B 307 -35.448 -18.552-106.765 1.00 43.85 C +ATOM 8436 C VAL B 307 -36.451 -19.287-105.886 1.00 44.55 C +ATOM 8437 O VAL B 307 -36.220 -19.465-104.684 1.00 45.81 O +ATOM 8438 CB VAL B 307 -34.243 -19.452-107.095 1.00 42.07 C +ATOM 8439 CG1 VAL B 307 -34.696 -20.710-107.807 1.00 39.35 C +ATOM 8440 CG2 VAL B 307 -33.231 -18.694-107.930 1.00 41.04 C +ATOM 8441 N SER B 308 -37.551 -19.724-106.489 1.00 44.16 N +ATOM 8442 CA SER B 308 -38.617 -20.378-105.755 1.00 45.17 C +ATOM 8443 C SER B 308 -38.258 -21.817-105.435 1.00 45.12 C +ATOM 8444 O SER B 308 -37.343 -22.389-106.031 1.00 46.97 O +ATOM 8445 CB SER B 308 -39.908 -20.374-106.570 1.00 48.01 C +ATOM 8446 OG SER B 308 -40.465 -19.082-106.670 1.00 59.07 O +ATOM 8447 N PRO B 309 -38.972 -22.433-104.491 1.00 47.75 N +ATOM 8448 CA PRO B 309 -38.872 -23.890-104.352 1.00 48.99 C +ATOM 8449 C PRO B 309 -39.247 -24.617-105.626 1.00 53.87 C +ATOM 8450 O PRO B 309 -38.798 -25.749-105.835 1.00 62.81 O +ATOM 8451 CB PRO B 309 -39.859 -24.203-103.222 1.00 44.19 C +ATOM 8452 CG PRO B 309 -39.929 -22.950-102.431 1.00 46.07 C +ATOM 8453 CD PRO B 309 -39.782 -21.830-103.418 1.00 45.67 C +ATOM 8454 N ALA B 310 -40.027 -23.987-106.502 1.00 47.31 N +ATOM 8455 CA ALA B 310 -40.341 -24.540-107.809 1.00 50.48 C +ATOM 8456 C ALA B 310 -39.297 -24.183-108.852 1.00 49.53 C +ATOM 8457 O ALA B 310 -39.495 -24.476-110.036 1.00 47.81 O +ATOM 8458 CB ALA B 310 -41.720 -24.068-108.269 1.00 55.04 C +ATOM 8459 N SER B 311 -38.200 -23.551-108.436 1.00 49.34 N +ATOM 8460 CA SER B 311 -37.092 -23.209-109.323 1.00 50.09 C +ATOM 8461 C SER B 311 -37.536 -22.204-110.385 1.00 44.93 C +ATOM 8462 O SER B 311 -37.333 -22.395-111.585 1.00 44.74 O +ATOM 8463 CB SER B 311 -36.496 -24.468-109.957 1.00 51.53 C +ATOM 8464 OG SER B 311 -36.240 -25.445-108.961 1.00 56.43 O +ATOM 8465 N ASN B 312 -38.145 -21.117-109.922 1.00 44.80 N +ATOM 8466 CA ASN B 312 -38.593 -20.026-110.773 1.00 43.00 C +ATOM 8467 C ASN B 312 -37.919 -18.729-110.348 1.00 42.75 C +ATOM 8468 O ASN B 312 -37.738 -18.474-109.153 1.00 47.07 O +ATOM 8469 CB ASN B 312 -40.116 -19.868-110.711 1.00 44.53 C +ATOM 8470 CG ASN B 312 -40.850 -21.072-111.269 1.00 51.09 C +ATOM 8471 OD1 ASN B 312 -40.311 -21.809-112.090 1.00 55.90 O +ATOM 8472 ND2 ASN B 312 -42.089 -21.270-110.833 1.00 54.48 N +ATOM 8473 N VAL B 313 -37.528 -17.921-111.327 1.00 38.00 N +ATOM 8474 CA VAL B 313 -36.956 -16.611-111.039 1.00 38.00 C +ATOM 8475 C VAL B 313 -38.091 -15.667-110.680 1.00 38.26 C +ATOM 8476 O VAL B 313 -38.979 -15.411-111.498 1.00 39.32 O +ATOM 8477 CB VAL B 313 -36.150 -16.071-112.225 1.00 41.46 C +ATOM 8478 CG1 VAL B 313 -35.678 -14.660-111.920 1.00 42.32 C +ATOM 8479 CG2 VAL B 313 -34.967 -16.976-112.524 1.00 52.40 C +ATOM 8480 N CYS B 314 -38.076 -15.168-109.449 1.00 45.09 N +ATOM 8481 CA CYS B 314 -39.105 -14.275-108.950 1.00 44.83 C +ATOM 8482 C CYS B 314 -38.479 -12.972-108.478 1.00 44.34 C +ATOM 8483 O CYS B 314 -37.292 -12.906-108.144 1.00 46.73 O +ATOM 8484 CB CYS B 314 -39.871 -14.910-107.794 1.00 47.12 C +ATOM 8485 SG CYS B 314 -40.324 -16.626-108.063 1.00 59.48 S +ATOM 8486 N PHE B 315 -39.305 -11.934-108.438 1.00 38.77 N +ATOM 8487 CA PHE B 315 -38.919 -10.668-107.840 1.00 39.44 C +ATOM 8488 C PHE B 315 -40.170 -10.049-107.241 1.00 38.28 C +ATOM 8489 O PHE B 315 -41.287 -10.514-107.476 1.00 42.84 O +ATOM 8490 CB PHE B 315 -38.231 -9.740-108.851 1.00 42.49 C +ATOM 8491 CG PHE B 315 -39.143 -9.188-109.922 1.00 45.47 C +ATOM 8492 CD1 PHE B 315 -39.952 -10.020-110.685 1.00 46.43 C +ATOM 8493 CD2 PHE B 315 -39.173 -7.825-110.177 1.00 41.70 C +ATOM 8494 CE1 PHE B 315 -40.779 -9.498-111.671 1.00 41.62 C +ATOM 8495 CE2 PHE B 315 -39.994 -7.300-111.158 1.00 42.56 C +ATOM 8496 CZ PHE B 315 -40.798 -8.139-111.906 1.00 43.92 C +ATOM 8497 N PHE B 316 -39.975 -8.994-106.455 1.00 39.06 N +ATOM 8498 CA PHE B 316 -41.055 -8.463-105.636 1.00 45.27 C +ATOM 8499 C PHE B 316 -40.806 -6.992-105.351 1.00 49.30 C +ATOM 8500 O PHE B 316 -39.694 -6.485-105.524 1.00 48.20 O +ATOM 8501 CB PHE B 316 -41.181 -9.235-104.316 1.00 46.51 C +ATOM 8502 CG PHE B 316 -39.918 -9.230-103.485 1.00 49.07 C +ATOM 8503 CD1 PHE B 316 -39.651 -8.197-102.597 1.00 51.14 C +ATOM 8504 CD2 PHE B 316 -38.994 -10.253-103.604 1.00 48.30 C +ATOM 8505 CE1 PHE B 316 -38.495 -8.192-101.838 1.00 45.55 C +ATOM 8506 CE2 PHE B 316 -37.835 -10.252-102.849 1.00 51.64 C +ATOM 8507 CZ PHE B 316 -37.585 -9.219-101.966 1.00 47.81 C +ATOM 8508 N ALA B 317 -41.856 -6.312-104.893 1.00 43.37 N +ATOM 8509 CA ALA B 317 -41.706 -4.959-104.378 1.00 49.37 C +ATOM 8510 C ALA B 317 -41.197 -5.015-102.940 1.00 58.91 C +ATOM 8511 O ALA B 317 -41.729 -5.765-102.113 1.00 57.70 O +ATOM 8512 CB ALA B 317 -43.032 -4.208-104.452 1.00 47.12 C +ATOM 8513 N LYS B 318 -40.171 -4.209-102.642 1.00 60.61 N +ATOM 8514 CA LYS B 318 -39.463 -4.333-101.368 1.00 49.64 C +ATOM 8515 C LYS B 318 -40.398 -4.099-100.191 1.00 44.84 C +ATOM 8516 O LYS B 318 -40.435 -4.894 -99.247 1.00 48.17 O +ATOM 8517 CB LYS B 318 -38.288 -3.352-101.321 1.00 52.45 C +ATOM 8518 CG LYS B 318 -37.335 -3.524-100.139 1.00 49.15 C +ATOM 8519 CD LYS B 318 -36.300 -4.616-100.417 1.00 58.56 C +ATOM 8520 CE LYS B 318 -35.287 -4.768 -99.280 1.00 54.93 C +ATOM 8521 NZ LYS B 318 -34.282 -5.841 -99.561 1.00 53.04 N +ATOM 8522 N CYS B 319 -41.177 -3.015-100.238 1.00 48.49 N +ATOM 8523 CA CYS B 319 -42.014 -2.673 -99.088 1.00 60.69 C +ATOM 8524 C CYS B 319 -43.210 -3.610 -98.941 1.00 56.15 C +ATOM 8525 O CYS B 319 -43.400 -4.162 -97.843 1.00 61.34 O +ATOM 8526 CB CYS B 319 -42.424 -1.195 -99.171 1.00 62.24 C +ATOM 8527 SG CYS B 319 -43.460 -0.539 -97.814 1.00 67.44 S +ATOM 8528 N PRO B 320 -44.037 -3.848 -99.965 1.00 49.32 N +ATOM 8529 CA PRO B 320 -45.185 -4.742 -99.757 1.00 45.11 C +ATOM 8530 C PRO B 320 -44.807 -6.155 -99.356 1.00 51.08 C +ATOM 8531 O PRO B 320 -45.559 -6.783 -98.603 1.00 59.48 O +ATOM 8532 CB PRO B 320 -45.899 -4.713-101.110 1.00 48.86 C +ATOM 8533 CG PRO B 320 -45.536 -3.420-101.678 1.00 54.32 C +ATOM 8534 CD PRO B 320 -44.115 -3.187-101.276 1.00 54.15 C +ATOM 8535 N TYR B 321 -43.685 -6.694 -99.842 1.00 51.64 N +ATOM 8536 CA TYR B 321 -43.281 -8.024 -99.392 1.00 57.92 C +ATOM 8537 C TYR B 321 -42.932 -8.014 -97.905 1.00 63.23 C +ATOM 8538 O TYR B 321 -43.287 -8.945 -97.173 1.00 57.92 O +ATOM 8539 CB TYR B 321 -42.109 -8.549-100.230 1.00 53.72 C +ATOM 8540 CG TYR B 321 -41.850 -10.044-100.087 1.00 51.63 C +ATOM 8541 CD1 TYR B 321 -42.770 -10.879 -99.465 1.00 56.53 C +ATOM 8542 CD2 TYR B 321 -40.667 -10.611-100.539 1.00 53.13 C +ATOM 8543 CE1 TYR B 321 -42.527 -12.237 -99.316 1.00 62.26 C +ATOM 8544 CE2 TYR B 321 -40.414 -11.969-100.395 1.00 60.54 C +ATOM 8545 CZ TYR B 321 -41.349 -12.777 -99.782 1.00 62.43 C +ATOM 8546 OH TYR B 321 -41.111 -14.127 -99.626 1.00 58.23 O +ATOM 8547 N MET B 322 -42.250 -6.966 -97.436 1.00 65.32 N +ATOM 8548 CA MET B 322 -41.899 -6.887 -96.020 1.00 67.49 C +ATOM 8549 C MET B 322 -43.143 -6.870 -95.142 1.00 63.61 C +ATOM 8550 O MET B 322 -43.212 -7.577 -94.130 1.00 72.90 O +ATOM 8551 CB MET B 322 -41.045 -5.649 -95.759 1.00 71.69 C +ATOM 8552 CG MET B 322 -40.927 -5.277 -94.293 1.00 75.71 C +ATOM 8553 SD MET B 322 -39.539 -4.176 -94.012 1.00115.48 S +ATOM 8554 CE MET B 322 -39.586 -3.200 -95.513 1.00 71.14 C +ATOM 8555 N CYS B 323 -44.139 -6.070 -95.515 1.00 54.91 N +ATOM 8556 CA CYS B 323 -45.393 -6.025 -94.776 1.00 57.69 C +ATOM 8557 C CYS B 323 -46.301 -7.207 -95.087 1.00 57.11 C +ATOM 8558 O CYS B 323 -47.402 -7.282 -94.529 1.00 58.57 O +ATOM 8559 CB CYS B 323 -46.128 -4.716 -95.068 1.00 57.98 C +ATOM 8560 SG CYS B 323 -45.272 -3.242 -94.481 1.00 68.37 S +ATOM 8561 N LYS B 324 -45.877 -8.108 -95.976 1.00 54.67 N +ATOM 8562 CA LYS B 324 -46.655 -9.292 -96.339 1.00 52.29 C +ATOM 8563 C LYS B 324 -48.060 -8.916 -96.795 1.00 53.30 C +ATOM 8564 O LYS B 324 -49.028 -9.631 -96.527 1.00 57.00 O +ATOM 8565 CB LYS B 324 -46.710 -10.300 -95.188 1.00 51.63 C +ATOM 8566 CG LYS B 324 -45.345 -10.696 -94.649 1.00 59.35 C +ATOM 8567 CD LYS B 324 -44.524 -11.466 -95.677 1.00 62.74 C +ATOM 8568 CE LYS B 324 -43.050 -11.518 -95.274 1.00 65.51 C +ATOM 8569 NZ LYS B 324 -42.278 -12.588 -95.979 1.00 63.07 N +ATOM 8570 N THR B 325 -48.182 -7.773 -97.468 1.00 50.52 N +ATOM 8571 CA THR B 325 -49.451 -7.375 -98.059 1.00 52.38 C +ATOM 8572 C THR B 325 -49.629 -7.932 -99.467 1.00 54.22 C +ATOM 8573 O THR B 325 -50.765 -8.175 -99.892 1.00 50.47 O +ATOM 8574 CB THR B 325 -49.578 -5.843 -98.067 1.00 51.43 C +ATOM 8575 OG1 THR B 325 -50.250 -5.412 -99.257 1.00 57.99 O +ATOM 8576 CG2 THR B 325 -48.223 -5.181 -97.991 1.00 50.28 C +ATOM 8577 N GLU B 326 -48.536 -8.172-100.189 1.00 55.23 N +ATOM 8578 CA GLU B 326 -48.598 -8.814-101.492 1.00 52.64 C +ATOM 8579 C GLU B 326 -47.495 -9.865-101.578 1.00 54.33 C +ATOM 8580 O GLU B 326 -46.638 -9.974-100.695 1.00 44.26 O +ATOM 8581 CB GLU B 326 -48.494 -7.778-102.618 1.00 50.21 C +ATOM 8582 CG GLU B 326 -47.078 -7.394-102.960 1.00 56.28 C +ATOM 8583 CD GLU B 326 -46.990 -6.445-104.139 1.00 58.25 C +ATOM 8584 OE1 GLU B 326 -47.879 -5.579-104.284 1.00 56.45 O +ATOM 8585 OE2 GLU B 326 -46.030 -6.575-104.929 1.00 59.83 O +ATOM 8586 N TYR B 327 -47.521 -10.647-102.657 1.00 60.73 N +ATOM 8587 CA TYR B 327 -46.564 -11.725-102.856 1.00 55.92 C +ATOM 8588 C TYR B 327 -45.506 -11.314-103.878 1.00 55.48 C +ATOM 8589 O TYR B 327 -45.416 -10.146-104.272 1.00 57.72 O +ATOM 8590 CB TYR B 327 -47.300 -12.992-103.311 1.00 55.78 C +ATOM 8591 CG TYR B 327 -48.396 -13.466-102.387 1.00 61.10 C +ATOM 8592 CD1 TYR B 327 -48.294 -13.310-101.011 1.00 66.71 C +ATOM 8593 CD2 TYR B 327 -49.539 -14.072-102.897 1.00 55.63 C +ATOM 8594 CE1 TYR B 327 -49.302 -13.747-100.168 1.00 62.41 C +ATOM 8595 CE2 TYR B 327 -50.548 -14.510-102.065 1.00 51.52 C +ATOM 8596 CZ TYR B 327 -50.426 -14.346-100.704 1.00 55.09 C +ATOM 8597 OH TYR B 327 -51.438 -14.787 -99.886 1.00 53.14 O +ATOM 8598 N ALA B 328 -44.739 -12.282-104.356 1.00 51.06 N +ATOM 8599 CA ALA B 328 -43.785 -12.046-105.422 1.00 45.23 C +ATOM 8600 C ALA B 328 -44.446 -12.381-106.751 1.00 49.59 C +ATOM 8601 O ALA B 328 -45.560 -12.906-106.807 1.00 53.08 O +ATOM 8602 CB ALA B 328 -42.515 -12.877-105.214 1.00 38.00 C +ATOM 8603 N VAL B 329 -43.740 -12.070-107.829 1.00 46.65 N +ATOM 8604 CA VAL B 329 -44.211 -12.310-109.184 1.00 38.00 C +ATOM 8605 C VAL B 329 -43.171 -13.201-109.830 1.00 38.00 C +ATOM 8606 O VAL B 329 -42.017 -12.789-109.994 1.00 41.44 O +ATOM 8607 CB VAL B 329 -44.401 -11.013-109.978 1.00 38.00 C +ATOM 8608 CG1 VAL B 329 -44.897 -11.325-111.364 1.00 48.10 C +ATOM 8609 CG2 VAL B 329 -45.385 -10.099-109.274 1.00 42.39 C +ATOM 8610 N CYS B 330 -43.536 -14.449-110.093 1.00 40.80 N +ATOM 8611 CA CYS B 330 -42.603 -15.421-110.643 1.00 49.94 C +ATOM 8612 C CYS B 330 -42.820 -15.657-112.130 1.00 51.13 C +ATOM 8613 O CYS B 330 -43.948 -15.642-112.628 1.00 62.87 O +ATOM 8614 CB CYS B 330 -42.714 -16.753-109.913 1.00 50.27 C +ATOM 8615 SG CYS B 330 -42.352 -16.638-108.175 1.00 64.67 S +ATOM 8616 N GLY B 331 -41.720 -15.914-112.831 1.00 39.94 N +ATOM 8617 CA GLY B 331 -41.788 -16.465-114.164 1.00 48.72 C +ATOM 8618 C GLY B 331 -42.022 -17.965-114.143 1.00 50.47 C +ATOM 8619 O GLY B 331 -42.157 -18.596-113.094 1.00 48.05 O +ATOM 8620 N LYS B 332 -42.091 -18.541-115.342 1.00 52.91 N +ATOM 8621 CA LYS B 332 -42.279 -19.980-115.525 1.00 51.18 C +ATOM 8622 C LYS B 332 -41.267 -20.502-116.541 1.00 49.80 C +ATOM 8623 O LYS B 332 -41.619 -20.812-117.685 1.00 49.15 O +ATOM 8624 CB LYS B 332 -43.711 -20.298-115.964 1.00 54.58 C +ATOM 8625 CG LYS B 332 -44.575 -20.946-114.880 1.00 72.08 C +ATOM 8626 CD LYS B 332 -44.948 -19.937-113.787 1.00 84.09 C +ATOM 8627 CE LYS B 332 -45.957 -20.499-112.782 1.00 80.87 C +ATOM 8628 NZ LYS B 332 -45.422 -21.648-111.993 1.00 71.78 N +ATOM 8629 N PRO B 333 -39.981 -20.591-116.160 1.00 48.34 N +ATOM 8630 CA PRO B 333 -39.400 -20.104-114.909 1.00 40.66 C +ATOM 8631 C PRO B 333 -38.852 -18.695-115.072 1.00 43.13 C +ATOM 8632 O PRO B 333 -38.675 -17.993-114.085 1.00 46.82 O +ATOM 8633 CB PRO B 333 -38.268 -21.092-114.634 1.00 38.00 C +ATOM 8634 CG PRO B 333 -37.914 -21.670-115.975 1.00 47.86 C +ATOM 8635 CD PRO B 333 -38.967 -21.263-116.987 1.00 53.02 C +ATOM 8636 N HIS B 334 -38.555 -18.296-116.308 1.00 44.29 N +ATOM 8637 CA HIS B 334 -38.072 -16.953-116.587 1.00 44.46 C +ATOM 8638 C HIS B 334 -39.084 -16.066-117.298 1.00 43.81 C +ATOM 8639 O HIS B 334 -38.966 -14.840-117.215 1.00 41.99 O +ATOM 8640 CB HIS B 334 -36.787 -17.016-117.425 1.00 48.97 C +ATOM 8641 CG HIS B 334 -35.674 -17.777-116.772 1.00 46.82 C +ATOM 8642 ND1 HIS B 334 -34.708 -17.174-115.993 1.00 47.53 N +ATOM 8643 CD2 HIS B 334 -35.378 -19.099-116.781 1.00 47.76 C +ATOM 8644 CE1 HIS B 334 -33.862 -18.091-115.557 1.00 54.65 C +ATOM 8645 NE2 HIS B 334 -34.247 -19.267-116.019 1.00 58.81 N +ATOM 8646 N LEU B 335 -40.053 -16.645-118.007 1.00 45.76 N +ATOM 8647 CA LEU B 335 -40.974 -15.869-118.829 1.00 43.32 C +ATOM 8648 C LEU B 335 -42.101 -15.293-117.984 1.00 42.99 C +ATOM 8649 O LEU B 335 -42.793 -16.026-117.271 1.00 45.61 O +ATOM 8650 CB LEU B 335 -41.561 -16.725-119.950 1.00 43.25 C +ATOM 8651 CG LEU B 335 -40.617 -17.113-121.085 1.00 43.47 C +ATOM 8652 CD1 LEU B 335 -39.752 -15.920-121.452 1.00 38.00 C +ATOM 8653 CD2 LEU B 335 -39.774 -18.334-120.719 1.00 56.67 C +ATOM 8654 N LEU B 336 -42.293 -13.981-118.083 1.00 41.54 N +ATOM 8655 CA LEU B 336 -43.354 -13.280-117.378 1.00 38.05 C +ATOM 8656 C LEU B 336 -43.913 -12.193-118.280 1.00 38.92 C +ATOM 8657 O LEU B 336 -43.152 -11.459-118.919 1.00 41.00 O +ATOM 8658 CB LEU B 336 -42.832 -12.661-116.082 1.00 40.42 C +ATOM 8659 CG LEU B 336 -43.761 -11.650-115.428 1.00 38.00 C +ATOM 8660 CD1 LEU B 336 -44.946 -12.378-114.826 1.00 42.52 C +ATOM 8661 CD2 LEU B 336 -43.006 -10.851-114.390 1.00 38.00 C +ATOM 8662 N GLU B 337 -45.238 -12.086-118.331 1.00 39.38 N +ATOM 8663 CA GLU B 337 -45.887 -11.102-119.187 1.00 42.12 C +ATOM 8664 C GLU B 337 -46.285 -9.863-118.395 1.00 38.00 C +ATOM 8665 O GLU B 337 -46.696 -9.955-117.236 1.00 38.00 O +ATOM 8666 CB GLU B 337 -47.107 -11.702-119.893 1.00 41.79 C +ATOM 8667 CG GLU B 337 -48.222 -12.177-118.989 1.00 43.98 C +ATOM 8668 CD GLU B 337 -49.436 -12.613-119.786 1.00 41.04 C +ATOM 8669 OE1 GLU B 337 -49.322 -13.591-120.553 1.00 38.00 O +ATOM 8670 OE2 GLU B 337 -50.503 -11.976-119.651 1.00 40.48 O +ATOM 8671 N GLY B 338 -46.175 -8.704-119.043 1.00 38.00 N +ATOM 8672 CA GLY B 338 -46.473 -7.424-118.439 1.00 38.00 C +ATOM 8673 C GLY B 338 -46.927 -6.438-119.492 1.00 38.00 C +ATOM 8674 O GLY B 338 -47.091 -6.785-120.662 1.00 38.00 O +ATOM 8675 N SER B 339 -47.139 -5.197-119.070 1.00 38.00 N +ATOM 8676 CA SER B 339 -47.628 -4.150-119.958 1.00 38.00 C +ATOM 8677 C SER B 339 -46.675 -2.968-119.921 1.00 38.00 C +ATOM 8678 O SER B 339 -46.481 -2.361-118.863 1.00 39.60 O +ATOM 8679 CB SER B 339 -49.023 -3.690-119.546 1.00 38.66 C +ATOM 8680 OG SER B 339 -48.955 -2.954-118.339 1.00 38.00 O +ATOM 8681 N LEU B 340 -46.121 -2.612-121.074 1.00 38.00 N +ATOM 8682 CA LEU B 340 -45.219 -1.472-121.180 1.00 38.00 C +ATOM 8683 C LEU B 340 -45.991 -0.256-121.674 1.00 39.79 C +ATOM 8684 O LEU B 340 -46.586 -0.291-122.756 1.00 41.85 O +ATOM 8685 CB LEU B 340 -44.055 -1.780-122.118 1.00 38.00 C +ATOM 8686 CG LEU B 340 -43.240 -3.008-121.735 1.00 38.00 C +ATOM 8687 CD1 LEU B 340 -43.515 -4.128-122.707 1.00 38.00 C +ATOM 8688 CD2 LEU B 340 -41.770 -2.673-121.705 1.00 41.51 C +ATOM 8689 N SER B 341 -45.961 0.818-120.894 1.00 40.29 N +ATOM 8690 CA SER B 341 -46.642 2.063-121.224 1.00 38.00 C +ATOM 8691 C SER B 341 -45.597 3.083-121.659 1.00 38.00 C +ATOM 8692 O SER B 341 -44.642 3.345-120.923 1.00 38.00 O +ATOM 8693 CB SER B 341 -47.451 2.566-120.026 1.00 38.00 C +ATOM 8694 OG SER B 341 -48.251 3.690-120.353 1.00 40.71 O +ATOM 8695 N ALA B 342 -45.766 3.630-122.863 1.00 38.21 N +ATOM 8696 CA ALA B 342 -44.771 4.535-123.426 1.00 38.00 C +ATOM 8697 C ALA B 342 -44.530 5.720-122.508 1.00 38.00 C +ATOM 8698 O ALA B 342 -45.450 6.236-121.874 1.00 38.00 O +ATOM 8699 CB ALA B 342 -45.214 5.031-124.799 1.00 38.00 C +ATOM 8700 N PHE B 343 -43.281 6.157-122.451 1.00 38.00 N +ATOM 8701 CA PHE B 343 -42.895 7.224-121.546 1.00 40.23 C +ATOM 8702 C PHE B 343 -43.276 8.576-122.122 1.00 43.63 C +ATOM 8703 O PHE B 343 -43.088 8.832-123.313 1.00 50.58 O +ATOM 8704 CB PHE B 343 -41.391 7.181-121.295 1.00 43.46 C +ATOM 8705 CG PHE B 343 -41.027 6.977-119.861 1.00 46.02 C +ATOM 8706 CD1 PHE B 343 -41.383 5.813-119.208 1.00 44.58 C +ATOM 8707 CD2 PHE B 343 -40.321 7.944-119.168 1.00 46.93 C +ATOM 8708 CE1 PHE B 343 -41.051 5.619-117.888 1.00 48.64 C +ATOM 8709 CE2 PHE B 343 -39.982 7.756-117.852 1.00 49.59 C +ATOM 8710 CZ PHE B 343 -40.348 6.592-117.209 1.00 51.91 C +ATOM 8711 N LEU B 344 -43.805 9.446-121.268 1.00 44.43 N +ATOM 8712 CA LEU B 344 -44.053 10.814-121.672 1.00 43.03 C +ATOM 8713 C LEU B 344 -42.728 11.569-121.783 1.00 41.31 C +ATOM 8714 O LEU B 344 -41.696 11.102-121.295 1.00 39.12 O +ATOM 8715 CB LEU B 344 -44.995 11.490-120.678 1.00 44.35 C +ATOM 8716 CG LEU B 344 -46.404 10.900-120.556 1.00 38.00 C +ATOM 8717 CD1 LEU B 344 -47.241 11.719-119.592 1.00 38.00 C +ATOM 8718 CD2 LEU B 344 -47.083 10.816-121.908 1.00 38.00 C +ATOM 8719 N PRO B 345 -42.721 12.717-122.464 1.00 45.68 N +ATOM 8720 CA PRO B 345 -41.493 13.518-122.548 1.00 46.57 C +ATOM 8721 C PRO B 345 -41.003 13.957-121.174 1.00 52.94 C +ATOM 8722 O PRO B 345 -41.768 14.056-120.210 1.00 53.37 O +ATOM 8723 CB PRO B 345 -41.912 14.722-123.399 1.00 48.09 C +ATOM 8724 CG PRO B 345 -43.048 14.220-124.220 1.00 45.97 C +ATOM 8725 CD PRO B 345 -43.783 13.251-123.336 1.00 47.65 C +ATOM 8726 N SER B 346 -39.703 14.246-121.105 1.00 53.99 N +ATOM 8727 CA SER B 346 -39.067 14.591-119.839 1.00 55.65 C +ATOM 8728 C SER B 346 -39.682 15.841-119.235 1.00 49.52 C +ATOM 8729 O SER B 346 -40.005 16.798-119.943 1.00 51.45 O +ATOM 8730 CB SER B 346 -37.567 14.809-120.036 1.00 55.51 C +ATOM 8731 OG SER B 346 -36.933 13.624-120.473 1.00 66.61 O +ATOM 8732 N LEU B 347 -39.820 15.840-117.907 1.00 50.61 N +ATOM 8733 CA LEU B 347 -40.400 16.991-117.228 1.00 56.54 C +ATOM 8734 C LEU B 347 -39.543 18.239-117.344 1.00 58.94 C +ATOM 8735 O LEU B 347 -40.025 19.332-117.026 1.00 55.75 O +ATOM 8736 CB LEU B 347 -40.632 16.684-115.752 1.00 51.58 C +ATOM 8737 CG LEU B 347 -41.736 15.669-115.502 1.00 52.29 C +ATOM 8738 CD1 LEU B 347 -41.158 14.460-114.794 1.00 51.01 C +ATOM 8739 CD2 LEU B 347 -42.866 16.314-114.716 1.00 49.91 C +ATOM 8740 N ASN B 348 -38.295 18.107-117.785 1.00 62.44 N +ATOM 8741 CA ASN B 348 -37.476 19.273-118.073 1.00 56.39 C +ATOM 8742 C ASN B 348 -37.870 19.929-119.383 1.00 56.87 C +ATOM 8743 O ASN B 348 -37.590 21.116-119.577 1.00 65.77 O +ATOM 8744 CB ASN B 348 -36.002 18.869-118.108 1.00 57.46 C +ATOM 8745 CG ASN B 348 -35.505 18.350-116.769 1.00 64.25 C +ATOM 8746 OD1 ASN B 348 -36.006 18.737-115.709 1.00 57.46 O +ATOM 8747 ND2 ASN B 348 -34.544 17.433-116.814 1.00 63.02 N +ATOM 8748 N LEU B 349 -38.543 19.195-120.267 1.00 55.84 N +ATOM 8749 CA LEU B 349 -38.999 19.732-121.542 1.00 51.10 C +ATOM 8750 C LEU B 349 -40.484 20.045-121.560 1.00 53.85 C +ATOM 8751 O LEU B 349 -40.891 21.022-122.195 1.00 61.43 O +ATOM 8752 CB LEU B 349 -38.694 18.741-122.671 1.00 47.56 C +ATOM 8753 CG LEU B 349 -37.227 18.382-122.888 1.00 46.64 C +ATOM 8754 CD1 LEU B 349 -37.082 17.366-124.006 1.00 40.82 C +ATOM 8755 CD2 LEU B 349 -36.437 19.643-123.188 1.00 50.89 C +ATOM 8756 N ALA B 350 -41.295 19.264-120.850 1.00 54.29 N +ATOM 8757 CA ALA B 350 -42.743 19.457-120.827 1.00 54.25 C +ATOM 8758 C ALA B 350 -43.218 19.247-119.401 1.00 51.25 C +ATOM 8759 O ALA B 350 -43.632 18.143-119.022 1.00 50.77 O +ATOM 8760 CB ALA B 350 -43.454 18.506-121.790 1.00 53.50 C +ATOM 8761 N PRO B 351 -43.182 20.297-118.580 1.00 45.47 N +ATOM 8762 CA PRO B 351 -43.582 20.149-117.179 1.00 51.81 C +ATOM 8763 C PRO B 351 -45.040 19.736-117.068 1.00 53.32 C +ATOM 8764 O PRO B 351 -45.875 20.080-117.907 1.00 53.03 O +ATOM 8765 CB PRO B 351 -43.348 21.546-116.591 1.00 54.02 C +ATOM 8766 CG PRO B 351 -42.414 22.225-117.560 1.00 46.50 C +ATOM 8767 CD PRO B 351 -42.751 21.667-118.897 1.00 38.34 C +ATOM 8768 N ARG B 352 -45.341 18.985-116.017 1.00 49.62 N +ATOM 8769 CA ARG B 352 -46.688 18.494-115.796 1.00 50.32 C +ATOM 8770 C ARG B 352 -47.176 18.960-114.435 1.00 51.55 C +ATOM 8771 O ARG B 352 -46.395 19.397-113.585 1.00 49.93 O +ATOM 8772 CB ARG B 352 -46.750 16.969-115.900 1.00 50.44 C +ATOM 8773 CG ARG B 352 -46.308 16.456-117.253 1.00 48.87 C +ATOM 8774 CD ARG B 352 -46.801 15.050-117.507 1.00 50.56 C +ATOM 8775 NE ARG B 352 -46.124 14.055-116.685 1.00 48.61 N +ATOM 8776 CZ ARG B 352 -44.941 13.531-116.979 1.00 50.89 C +ATOM 8777 NH1 ARG B 352 -44.292 13.918-118.069 1.00 52.03 N +ATOM 8778 NH2 ARG B 352 -44.405 12.621-116.180 1.00 56.86 N +ATOM 8779 N LEU B 353 -48.489 18.877-114.245 1.00 49.30 N +ATOM 8780 CA LEU B 353 -49.154 19.434-113.070 1.00 47.53 C +ATOM 8781 C LEU B 353 -50.136 18.386-112.558 1.00 49.95 C +ATOM 8782 O LEU B 353 -51.213 18.208-113.133 1.00 56.72 O +ATOM 8783 CB LEU B 353 -49.861 20.741-113.413 1.00 49.72 C +ATOM 8784 CG LEU B 353 -49.903 21.863-112.373 1.00 57.24 C +ATOM 8785 CD1 LEU B 353 -50.530 23.115-112.977 1.00 57.09 C +ATOM 8786 CD2 LEU B 353 -50.639 21.442-111.100 1.00 59.99 C +ATOM 8787 N SER B 354 -49.759 17.675-111.502 1.00 46.09 N +ATOM 8788 CA SER B 354 -50.673 16.725-110.879 1.00 44.86 C +ATOM 8789 C SER B 354 -51.778 17.504-110.176 1.00 45.69 C +ATOM 8790 O SER B 354 -51.516 18.225-109.208 1.00 43.44 O +ATOM 8791 CB SER B 354 -49.921 15.823-109.905 1.00 50.42 C +ATOM 8792 OG SER B 354 -50.659 14.646-109.619 1.00 47.21 O +ATOM 8793 N VAL B 355 -52.995 17.410-110.690 1.00 46.53 N +ATOM 8794 CA VAL B 355 -54.154 18.117-110.147 1.00 46.98 C +ATOM 8795 C VAL B 355 -55.033 17.109-109.421 1.00 45.59 C +ATOM 8796 O VAL B 355 -55.352 16.060-109.992 1.00 42.14 O +ATOM 8797 CB VAL B 355 -54.960 18.840-111.245 1.00 45.23 C +ATOM 8798 CG1 VAL B 355 -56.251 19.389-110.668 1.00 46.45 C +ATOM 8799 CG2 VAL B 355 -54.142 19.964-111.853 1.00 49.33 C +ATOM 8800 N PRO B 356 -55.453 17.386-108.186 1.00 51.54 N +ATOM 8801 CA PRO B 356 -56.373 16.473-107.502 1.00 49.22 C +ATOM 8802 C PRO B 356 -57.756 16.498-108.135 1.00 49.29 C +ATOM 8803 O PRO B 356 -58.264 17.549-108.536 1.00 49.33 O +ATOM 8804 CB PRO B 356 -56.404 17.008-106.066 1.00 46.06 C +ATOM 8805 CG PRO B 356 -56.040 18.446-106.193 1.00 48.34 C +ATOM 8806 CD PRO B 356 -55.061 18.521-107.332 1.00 50.14 C +ATOM 8807 N ASN B 357 -58.345 15.314-108.247 1.00 46.30 N +ATOM 8808 CA ASN B 357 -59.704 15.191-108.742 1.00 46.39 C +ATOM 8809 C ASN B 357 -60.656 15.955-107.821 1.00 48.18 C +ATOM 8810 O ASN B 357 -60.416 16.051-106.617 1.00 54.12 O +ATOM 8811 CB ASN B 357 -60.089 13.712-108.791 1.00 44.92 C +ATOM 8812 CG ASN B 357 -61.337 13.452-109.592 1.00 42.53 C +ATOM 8813 OD1 ASN B 357 -62.428 13.799-109.170 1.00 45.56 O +ATOM 8814 ND2 ASN B 357 -61.188 12.800-110.736 1.00 39.95 N +ATOM 8815 N PRO B 358 -61.729 16.542-108.358 1.00 45.56 N +ATOM 8816 CA PRO B 358 -62.782 17.068-107.476 1.00 44.85 C +ATOM 8817 C PRO B 358 -63.652 15.982-106.873 1.00 48.24 C +ATOM 8818 O PRO B 358 -64.420 16.271-105.947 1.00 57.11 O +ATOM 8819 CB PRO B 358 -63.603 17.980-108.400 1.00 45.31 C +ATOM 8820 CG PRO B 358 -62.713 18.267-109.544 1.00 53.23 C +ATOM 8821 CD PRO B 358 -61.876 17.038-109.733 1.00 49.79 C +ATOM 8822 N TRP B 359 -63.579 14.756-107.383 1.00 42.50 N +ATOM 8823 CA TRP B 359 -64.367 13.654-106.849 1.00 44.81 C +ATOM 8824 C TRP B 359 -63.448 12.581-106.280 1.00 42.18 C +ATOM 8825 O TRP B 359 -63.568 11.407-106.641 1.00 44.66 O +ATOM 8826 CB TRP B 359 -65.269 13.056-107.932 1.00 49.18 C +ATOM 8827 CG TRP B 359 -66.490 13.871-108.292 1.00 48.88 C +ATOM 8828 CD1 TRP B 359 -67.758 13.710-107.812 1.00 47.94 C +ATOM 8829 CD2 TRP B 359 -66.554 14.955-109.232 1.00 50.81 C +ATOM 8830 NE1 TRP B 359 -68.604 14.629-108.387 1.00 50.74 N +ATOM 8831 CE2 TRP B 359 -67.889 15.404-109.263 1.00 53.60 C +ATOM 8832 CE3 TRP B 359 -65.611 15.589-110.048 1.00 45.24 C +ATOM 8833 CZ2 TRP B 359 -68.301 16.459-110.076 1.00 52.89 C +ATOM 8834 CZ3 TRP B 359 -66.022 16.633-110.850 1.00 40.21 C +ATOM 8835 CH2 TRP B 359 -67.354 17.059-110.859 1.00 46.67 C +ATOM 8836 N ILE B 360 -62.505 12.969-105.418 1.00 44.32 N +ATOM 8837 CA ILE B 360 -61.652 11.966-104.790 1.00 47.43 C +ATOM 8838 C ILE B 360 -62.488 11.073-103.881 1.00 44.15 C +ATOM 8839 O ILE B 360 -63.594 11.420-103.456 1.00 45.79 O +ATOM 8840 CB ILE B 360 -60.499 12.605-103.999 1.00 44.62 C +ATOM 8841 CG1 ILE B 360 -60.258 14.050-104.439 1.00 49.64 C +ATOM 8842 CG2 ILE B 360 -59.243 11.756-104.129 1.00 38.00 C +ATOM 8843 CD1 ILE B 360 -60.980 15.111-103.590 1.00 53.04 C +ATOM 8844 N ARG B 361 -61.946 9.901-103.585 1.00 44.68 N +ATOM 8845 CA ARG B 361 -62.532 9.037-102.577 1.00 51.49 C +ATOM 8846 C ARG B 361 -61.907 9.319-101.214 1.00 59.07 C +ATOM 8847 O ARG B 361 -60.885 9.997-101.096 1.00 65.21 O +ATOM 8848 CB ARG B 361 -62.358 7.576-102.959 1.00 48.22 C +ATOM 8849 CG ARG B 361 -63.647 6.916-103.357 1.00 47.73 C +ATOM 8850 CD ARG B 361 -63.778 6.831-104.854 1.00 44.56 C +ATOM 8851 NE ARG B 361 -64.904 5.983-105.218 1.00 45.88 N +ATOM 8852 CZ ARG B 361 -65.302 5.758-106.463 1.00 50.76 C +ATOM 8853 NH1 ARG B 361 -64.663 6.323-107.480 1.00 57.58 N +ATOM 8854 NH2 ARG B 361 -66.338 4.964-106.690 1.00 50.37 N +ATOM 8855 N SER B 362 -62.550 8.800-100.165 1.00 51.06 N +ATOM 8856 CA SER B 362 -62.020 9.007 -98.823 1.00 53.01 C +ATOM 8857 C SER B 362 -60.698 8.279 -98.624 1.00 48.55 C +ATOM 8858 O SER B 362 -59.825 8.771 -97.900 1.00 45.40 O +ATOM 8859 CB SER B 362 -63.042 8.558 -97.777 1.00 59.89 C +ATOM 8860 OG SER B 362 -63.361 7.183 -97.915 1.00 64.10 O +ATOM 8861 N TYR B 363 -60.517 7.141 -99.290 1.00 49.59 N +ATOM 8862 CA TYR B 363 -59.358 6.277 -99.073 1.00 49.82 C +ATOM 8863 C TYR B 363 -59.251 5.883 -97.601 1.00 53.95 C +ATOM 8864 O TYR B 363 -58.188 5.971 -96.984 1.00 60.29 O +ATOM 8865 CB TYR B 363 -58.067 6.933 -99.569 1.00 51.86 C +ATOM 8866 CG TYR B 363 -57.967 7.001-101.076 1.00 54.48 C +ATOM 8867 CD1 TYR B 363 -57.526 5.908-101.819 1.00 50.66 C +ATOM 8868 CD2 TYR B 363 -58.323 8.154-101.756 1.00 57.89 C +ATOM 8869 CE1 TYR B 363 -57.442 5.974-103.200 1.00 51.72 C +ATOM 8870 CE2 TYR B 363 -58.245 8.228-103.131 1.00 61.15 C +ATOM 8871 CZ TYR B 363 -57.806 7.142-103.849 1.00 57.57 C +ATOM 8872 OH TYR B 363 -57.742 7.250-105.219 1.00 54.19 O +ATOM 8873 N THR B 364 -60.384 5.474 -97.030 1.00 54.05 N +ATOM 8874 CA THR B 364 -60.440 4.970 -95.665 1.00 53.20 C +ATOM 8875 C THR B 364 -61.436 3.822 -95.605 1.00 53.18 C +ATOM 8876 O THR B 364 -62.268 3.647 -96.499 1.00 56.20 O +ATOM 8877 CB THR B 364 -60.841 6.049 -94.651 1.00 52.75 C +ATOM 8878 OG1 THR B 364 -60.508 7.343 -95.164 1.00 53.45 O +ATOM 8879 CG2 THR B 364 -60.107 5.827 -93.328 1.00 56.30 C +ATOM 8880 N LEU B 365 -61.357 3.048 -94.520 1.00 47.61 N +ATOM 8881 CA LEU B 365 -62.287 1.942 -94.315 1.00 53.46 C +ATOM 8882 C LEU B 365 -63.721 2.411 -94.088 1.00 58.66 C +ATOM 8883 O LEU B 365 -64.649 1.598 -94.183 1.00 53.19 O +ATOM 8884 CB LEU B 365 -61.824 1.083 -93.134 1.00 54.79 C +ATOM 8885 CG LEU B 365 -60.483 0.359 -93.290 1.00 48.74 C +ATOM 8886 CD1 LEU B 365 -60.118 -0.438 -92.037 1.00 45.90 C +ATOM 8887 CD2 LEU B 365 -60.527 -0.547 -94.506 1.00 51.64 C +ATOM 8888 N ALA B 366 -63.923 3.698 -93.819 1.00 54.56 N +ATOM 8889 CA ALA B 366 -65.245 4.278 -93.653 1.00 45.35 C +ATOM 8890 C ALA B 366 -65.162 5.740 -94.065 1.00 57.16 C +ATOM 8891 O ALA B 366 -64.112 6.223 -94.499 1.00 62.52 O +ATOM 8892 CB ALA B 366 -65.747 4.124 -92.216 1.00 46.41 C +ATOM 8893 N GLY B 367 -66.287 6.441 -93.960 1.00 59.79 N +ATOM 8894 CA GLY B 367 -66.308 7.850 -94.299 1.00 63.49 C +ATOM 8895 C GLY B 367 -66.471 8.098 -95.783 1.00 55.47 C +ATOM 8896 O GLY B 367 -65.812 7.456 -96.606 1.00 49.60 O +ATOM 8897 N LYS B 368 -67.345 9.037 -96.133 1.00 52.95 N +ATOM 8898 CA LYS B 368 -67.623 9.385 -97.516 1.00 48.30 C +ATOM 8899 C LYS B 368 -67.275 10.846 -97.758 1.00 48.02 C +ATOM 8900 O LYS B 368 -67.290 11.665 -96.835 1.00 48.53 O +ATOM 8901 CB LYS B 368 -69.097 9.140 -97.876 1.00 44.46 C +ATOM 8902 CG LYS B 368 -69.910 8.460 -96.790 1.00 54.03 C +ATOM 8903 CD LYS B 368 -69.657 6.952 -96.723 1.00 57.46 C +ATOM 8904 CE LYS B 368 -70.278 6.225 -97.905 1.00 62.84 C +ATOM 8905 NZ LYS B 368 -70.191 4.747 -97.750 1.00 55.62 N +ATOM 8906 N GLU B 369 -66.950 11.163 -99.010 1.00 45.56 N +ATOM 8907 CA GLU B 369 -66.656 12.535 -99.380 1.00 43.09 C +ATOM 8908 C GLU B 369 -67.953 13.307 -99.611 1.00 45.12 C +ATOM 8909 O GLU B 369 -69.050 12.745 -99.625 1.00 46.28 O +ATOM 8910 CB GLU B 369 -65.756 12.568-100.610 1.00 45.46 C +ATOM 8911 CG GLU B 369 -64.337 12.105-100.332 1.00 47.32 C +ATOM 8912 CD GLU B 369 -63.575 13.057 -99.432 1.00 54.66 C +ATOM 8913 OE1 GLU B 369 -63.936 14.252 -99.387 1.00 62.84 O +ATOM 8914 OE2 GLU B 369 -62.619 12.610 -98.763 1.00 60.27 O +ATOM 8915 N GLU B 370 -67.816 14.616 -99.841 1.00 48.54 N +ATOM 8916 CA GLU B 370 -68.990 15.476 -99.953 1.00 51.20 C +ATOM 8917 C GLU B 370 -69.846 15.097-101.157 1.00 52.44 C +ATOM 8918 O GLU B 370 -71.078 15.054-101.059 1.00 49.11 O +ATOM 8919 CB GLU B 370 -68.557 16.941-100.031 1.00 52.64 C +ATOM 8920 CG GLU B 370 -69.338 17.870 -99.105 1.00 60.98 C +ATOM 8921 CD GLU B 370 -70.270 18.812 -99.854 1.00 62.85 C +ATOM 8922 OE1 GLU B 370 -69.775 19.636-100.655 1.00 55.81 O +ATOM 8923 OE2 GLU B 370 -71.500 18.723 -99.646 1.00 63.73 O +ATOM 8924 N TRP B 371 -69.210 14.813-102.299 1.00 53.95 N +ATOM 8925 CA TRP B 371 -69.958 14.427-103.494 1.00 55.56 C +ATOM 8926 C TRP B 371 -70.700 13.114-103.294 1.00 54.46 C +ATOM 8927 O TRP B 371 -71.716 12.860-103.955 1.00 54.29 O +ATOM 8928 CB TRP B 371 -69.019 14.310-104.694 1.00 49.93 C +ATOM 8929 CG TRP B 371 -67.987 13.224-104.567 1.00 48.77 C +ATOM 8930 CD1 TRP B 371 -66.725 13.352-104.070 1.00 48.90 C +ATOM 8931 CD2 TRP B 371 -68.129 11.845-104.950 1.00 46.11 C +ATOM 8932 NE1 TRP B 371 -66.071 12.144-104.120 1.00 48.47 N +ATOM 8933 CE2 TRP B 371 -66.912 11.203-104.655 1.00 43.75 C +ATOM 8934 CE3 TRP B 371 -69.165 11.095-105.513 1.00 47.95 C +ATOM 8935 CZ2 TRP B 371 -66.703 9.849-104.904 1.00 41.89 C +ATOM 8936 CZ3 TRP B 371 -68.954 9.750-105.759 1.00 43.30 C +ATOM 8937 CH2 TRP B 371 -67.735 9.142-105.455 1.00 40.31 C +ATOM 8938 N GLU B 372 -70.206 12.262-102.402 1.00 48.17 N +ATOM 8939 CA GLU B 372 -70.863 10.991-102.164 1.00 45.40 C +ATOM 8940 C GLU B 372 -72.212 11.148-101.477 1.00 48.48 C +ATOM 8941 O GLU B 372 -73.027 10.223-101.536 1.00 48.43 O +ATOM 8942 CB GLU B 372 -69.928 10.106-101.338 1.00 43.46 C +ATOM 8943 CG GLU B 372 -69.190 9.065-102.151 1.00 42.40 C +ATOM 8944 CD GLU B 372 -68.060 8.418-101.384 1.00 38.00 C +ATOM 8945 OE1 GLU B 372 -67.250 9.158-100.789 1.00 38.00 O +ATOM 8946 OE2 GLU B 372 -67.993 7.171-101.359 1.00 38.00 O +ATOM 8947 N VAL B 373 -72.495 12.314-100.895 1.00 52.03 N +ATOM 8948 CA VAL B 373 -73.690 12.500-100.076 1.00 55.68 C +ATOM 8949 C VAL B 373 -74.575 13.612-100.629 1.00 57.34 C +ATOM 8950 O VAL B 373 -75.804 13.563-100.494 1.00 50.70 O +ATOM 8951 CB VAL B 373 -73.302 12.792 -98.615 1.00 50.25 C +ATOM 8952 CG1 VAL B 373 -74.538 12.850 -97.730 1.00 52.58 C +ATOM 8953 CG2 VAL B 373 -72.331 11.734 -98.105 1.00 47.04 C +ATOM 8954 N ASN B 374 -73.962 14.616-101.262 1.00 58.47 N +ATOM 8955 CA ASN B 374 -74.685 15.791-101.730 1.00 56.92 C +ATOM 8956 C ASN B 374 -74.955 15.694-103.223 1.00 52.33 C +ATOM 8957 O ASN B 374 -74.027 15.894-104.020 1.00 53.38 O +ATOM 8958 CB ASN B 374 -73.890 17.059-101.416 1.00 50.39 C +ATOM 8959 CG ASN B 374 -74.525 18.306-101.996 1.00 53.90 C +ATOM 8960 OD1 ASN B 374 -75.710 18.320-102.332 1.00 54.78 O +ATOM 8961 ND2 ASN B 374 -73.741 19.370-102.104 1.00 57.31 N +ATOM 8962 N PRO B 375 -76.200 15.449-103.655 1.00 50.37 N +ATOM 8963 CA PRO B 375 -76.487 15.418-105.099 1.00 55.97 C +ATOM 8964 C PRO B 375 -76.290 16.755-105.789 1.00 54.94 C +ATOM 8965 O PRO B 375 -76.232 16.788-107.026 1.00 50.17 O +ATOM 8966 CB PRO B 375 -77.959 14.982-105.161 1.00 51.08 C +ATOM 8967 CG PRO B 375 -78.251 14.383-103.834 1.00 48.62 C +ATOM 8968 CD PRO B 375 -77.382 15.100-102.854 1.00 52.36 C +ATOM 8969 N LEU B 376 -76.190 17.851-105.038 1.00 51.97 N +ATOM 8970 CA LEU B 376 -75.922 19.170-105.598 1.00 58.06 C +ATOM 8971 C LEU B 376 -74.449 19.543-105.500 1.00 59.90 C +ATOM 8972 O LEU B 376 -74.113 20.731-105.443 1.00 65.66 O +ATOM 8973 CB LEU B 376 -76.786 20.225-104.909 1.00 59.91 C +ATOM 8974 CG LEU B 376 -78.297 20.056-105.067 1.00 64.05 C +ATOM 8975 CD1 LEU B 376 -79.023 20.964-104.101 1.00 69.04 C +ATOM 8976 CD2 LEU B 376 -78.727 20.355-106.499 1.00 57.85 C +ATOM 8977 N TYR B 377 -73.561 18.546-105.478 1.00 54.39 N +ATOM 8978 CA TYR B 377 -72.140 18.835-105.316 1.00 52.95 C +ATOM 8979 C TYR B 377 -71.599 19.646-106.485 1.00 57.47 C +ATOM 8980 O TYR B 377 -70.795 20.564-106.288 1.00 56.62 O +ATOM 8981 CB TYR B 377 -71.343 17.539-105.150 1.00 51.57 C +ATOM 8982 CG TYR B 377 -69.860 17.779-104.964 1.00 56.16 C +ATOM 8983 CD1 TYR B 377 -69.369 18.292-103.771 1.00 62.29 C +ATOM 8984 CD2 TYR B 377 -68.950 17.482-105.973 1.00 53.91 C +ATOM 8985 CE1 TYR B 377 -68.017 18.519-103.589 1.00 61.47 C +ATOM 8986 CE2 TYR B 377 -67.592 17.699-105.797 1.00 54.41 C +ATOM 8987 CZ TYR B 377 -67.133 18.221-104.603 1.00 59.24 C +ATOM 8988 OH TYR B 377 -65.788 18.449-104.417 1.00 62.16 O +ATOM 8989 N CYS B 378 -72.044 19.340-107.709 1.00 60.23 N +ATOM 8990 CA CYS B 378 -71.495 20.011-108.883 1.00 64.14 C +ATOM 8991 C CYS B 378 -71.924 21.470-108.973 1.00 66.37 C +ATOM 8992 O CYS B 378 -71.240 22.262-109.630 1.00 70.83 O +ATOM 8993 CB CYS B 378 -71.888 19.263-110.164 1.00 70.36 C +ATOM 8994 SG CYS B 378 -70.989 19.837-111.649 1.00 88.36 S +ATOM 8995 N ASP B 379 -73.023 21.850-108.320 1.00 65.61 N +ATOM 8996 CA ASP B 379 -73.377 23.264-108.255 1.00 68.45 C +ATOM 8997 C ASP B 379 -72.292 24.070-107.555 1.00 64.27 C +ATOM 8998 O ASP B 379 -72.110 25.257-107.850 1.00 62.78 O +ATOM 8999 CB ASP B 379 -74.719 23.435-107.548 1.00 73.51 C +ATOM 9000 CG ASP B 379 -75.885 23.016-108.415 1.00 70.11 C +ATOM 9001 OD1 ASP B 379 -75.765 23.111-109.655 1.00 68.16 O +ATOM 9002 OD2 ASP B 379 -76.913 22.581-107.857 1.00 71.10 O +ATOM 9003 N THR B 380 -71.560 23.438-106.637 1.00 61.26 N +ATOM 9004 CA THR B 380 -70.419 24.079-105.995 1.00 63.41 C +ATOM 9005 C THR B 380 -69.204 24.092-106.912 1.00 63.07 C +ATOM 9006 O THR B 380 -68.484 25.095-106.987 1.00 58.68 O +ATOM 9007 CB THR B 380 -70.074 23.345-104.698 1.00 58.76 C +ATOM 9008 OG1 THR B 380 -71.254 23.209-103.900 1.00 60.33 O +ATOM 9009 CG2 THR B 380 -69.019 24.121-103.909 1.00 50.77 C +ATOM 9010 N VAL B 381 -68.966 22.985-107.618 1.00 61.88 N +ATOM 9011 CA VAL B 381 -67.778 22.877-108.456 1.00 58.72 C +ATOM 9012 C VAL B 381 -67.823 23.907-109.575 1.00 61.72 C +ATOM 9013 O VAL B 381 -66.815 24.553-109.882 1.00 66.33 O +ATOM 9014 CB VAL B 381 -67.646 21.444-109.007 1.00 59.01 C +ATOM 9015 CG1 VAL B 381 -66.366 21.290-109.816 1.00 59.54 C +ATOM 9016 CG2 VAL B 381 -67.684 20.439-107.873 1.00 56.22 C +ATOM 9017 N LYS B 382 -69.006 24.121-110.159 1.00 57.31 N +ATOM 9018 CA LYS B 382 -69.144 25.033-111.290 1.00 55.25 C +ATOM 9019 C LYS B 382 -68.773 26.468-110.950 1.00 59.52 C +ATOM 9020 O LYS B 382 -68.593 27.275-111.869 1.00 57.10 O +ATOM 9021 CB LYS B 382 -70.578 24.998-111.825 1.00 53.71 C +ATOM 9022 CG LYS B 382 -70.981 23.679-112.458 1.00 56.04 C +ATOM 9023 CD LYS B 382 -72.389 23.749-113.026 1.00 57.07 C +ATOM 9024 CE LYS B 382 -72.804 22.427-113.648 1.00 54.63 C +ATOM 9025 NZ LYS B 382 -74.169 22.509-114.235 1.00 54.37 N +ATOM 9026 N GLN B 383 -68.645 26.803-109.666 1.00 63.11 N +ATOM 9027 CA GLN B 383 -68.320 28.154-109.228 1.00 64.05 C +ATOM 9028 C GLN B 383 -66.932 28.241-108.602 1.00 69.39 C +ATOM 9029 O GLN B 383 -66.633 29.214-107.902 1.00 69.40 O +ATOM 9030 CB GLN B 383 -69.381 28.655-108.248 1.00 60.96 C +ATOM 9031 CG GLN B 383 -70.789 28.625-108.819 1.00 61.78 C +ATOM 9032 CD GLN B 383 -71.849 28.985-107.798 1.00 67.18 C +ATOM 9033 OE1 GLN B 383 -71.669 28.779-106.598 1.00 64.41 O +ATOM 9034 NE2 GLN B 383 -72.969 29.515-108.273 1.00 73.54 N +ATOM 9035 N ILE B 384 -66.082 27.241-108.834 1.00 68.52 N +ATOM 9036 CA ILE B 384 -64.722 27.209-108.304 1.00 68.09 C +ATOM 9037 C ILE B 384 -63.745 27.181-109.474 1.00 71.55 C +ATOM 9038 O ILE B 384 -63.905 26.383-110.405 1.00 69.45 O +ATOM 9039 CB ILE B 384 -64.505 26.007-107.362 1.00 61.46 C +ATOM 9040 CG1 ILE B 384 -64.768 26.405-105.907 1.00 57.28 C +ATOM 9041 CG2 ILE B 384 -63.095 25.455-107.488 1.00 66.11 C +ATOM 9042 CD1 ILE B 384 -66.200 26.750-105.598 1.00 57.48 C +ATOM 9043 N TYR B 385 -62.756 28.074-109.438 1.00 68.71 N +ATOM 9044 CA TYR B 385 -61.704 28.076-110.446 1.00 68.80 C +ATOM 9045 C TYR B 385 -60.835 26.824-110.293 1.00 73.50 C +ATOM 9046 O TYR B 385 -60.547 26.399-109.168 1.00 68.54 O +ATOM 9047 CB TYR B 385 -60.854 29.345-110.310 1.00 65.16 C +ATOM 9048 CG TYR B 385 -59.636 29.410-111.208 1.00 69.38 C +ATOM 9049 CD1 TYR B 385 -59.720 29.945-112.487 1.00 73.76 C +ATOM 9050 CD2 TYR B 385 -58.396 28.954-110.769 1.00 67.83 C +ATOM 9051 CE1 TYR B 385 -58.606 30.006-113.311 1.00 73.95 C +ATOM 9052 CE2 TYR B 385 -57.279 29.014-111.584 1.00 57.81 C +ATOM 9053 CZ TYR B 385 -57.391 29.541-112.853 1.00 62.78 C +ATOM 9054 OH TYR B 385 -56.286 29.608-113.668 1.00 67.11 O +ATOM 9055 N PRO B 386 -60.378 26.219-111.406 1.00 72.88 N +ATOM 9056 CA PRO B 386 -60.594 26.644-112.793 1.00 71.99 C +ATOM 9057 C PRO B 386 -61.767 25.961-113.481 1.00 67.21 C +ATOM 9058 O PRO B 386 -61.747 25.815-114.701 1.00 70.10 O +ATOM 9059 CB PRO B 386 -59.284 26.247-113.469 1.00 71.85 C +ATOM 9060 CG PRO B 386 -58.918 24.973-112.767 1.00 69.30 C +ATOM 9061 CD PRO B 386 -59.424 25.096-111.337 1.00 64.96 C +ATOM 9062 N TYR B 387 -62.760 25.529-112.712 1.00 61.29 N +ATOM 9063 CA TYR B 387 -63.950 24.908-113.277 1.00 63.10 C +ATOM 9064 C TYR B 387 -65.038 25.918-113.629 1.00 66.63 C +ATOM 9065 O TYR B 387 -66.107 25.515-114.104 1.00 65.33 O +ATOM 9066 CB TYR B 387 -64.492 23.855-112.302 1.00 61.28 C +ATOM 9067 CG TYR B 387 -63.436 22.861-111.856 1.00 62.64 C +ATOM 9068 CD1 TYR B 387 -62.610 23.140-110.772 1.00 61.12 C +ATOM 9069 CD2 TYR B 387 -63.265 21.647-112.513 1.00 57.22 C +ATOM 9070 CE1 TYR B 387 -61.638 22.249-110.362 1.00 54.79 C +ATOM 9071 CE2 TYR B 387 -62.291 20.744-112.105 1.00 51.79 C +ATOM 9072 CZ TYR B 387 -61.483 21.053-111.028 1.00 48.69 C +ATOM 9073 OH TYR B 387 -60.514 20.172-110.606 1.00 39.71 O +ATOM 9074 N ASN B 388 -64.783 27.220-113.438 1.00 71.07 N +ATOM 9075 CA ASN B 388 -65.758 28.248-113.790 1.00 69.92 C +ATOM 9076 C ASN B 388 -65.826 28.512-115.289 1.00 68.96 C +ATOM 9077 O ASN B 388 -66.863 28.979-115.769 1.00 66.26 O +ATOM 9078 CB ASN B 388 -65.460 29.556-113.039 1.00 71.24 C +ATOM 9079 CG ASN B 388 -64.059 30.101-113.315 1.00 70.31 C +ATOM 9080 OD1 ASN B 388 -63.137 29.347-113.622 1.00 73.03 O +ATOM 9081 ND2 ASN B 388 -63.901 31.415-113.211 1.00 72.73 N +ATOM 9082 N ASN B 389 -64.752 28.225-116.033 1.00 76.91 N +ATOM 9083 CA ASN B 389 -64.741 28.425-117.479 1.00 87.65 C +ATOM 9084 C ASN B 389 -65.587 27.399-118.220 1.00 94.22 C +ATOM 9085 O ASN B 389 -65.762 27.535-119.438 1.00 90.04 O +ATOM 9086 CB ASN B 389 -63.305 28.384-118.025 1.00 84.09 C +ATOM 9087 CG ASN B 389 -62.589 27.071-117.719 1.00 83.17 C +ATOM 9088 OD1 ASN B 389 -62.890 26.030-118.307 1.00 75.78 O +ATOM 9089 ND2 ASN B 389 -61.615 27.126-116.817 1.00 83.08 N +ATOM 9090 N SER B 390 -66.089 26.374-117.523 1.00 92.23 N +ATOM 9091 CA SER B 390 -66.953 25.333-118.080 1.00 92.32 C +ATOM 9092 C SER B 390 -66.297 24.579-119.240 1.00 82.16 C +ATOM 9093 O SER B 390 -66.990 23.944-120.039 1.00 72.02 O +ATOM 9094 CB SER B 390 -68.317 25.897-118.506 1.00 97.82 C +ATOM 9095 OG SER B 390 -69.044 26.409-117.395 1.00 90.34 O +ATOM 9096 N GLN B 391 -64.970 24.632-119.347 1.00 78.67 N +ATOM 9097 CA GLN B 391 -64.225 23.843-120.321 1.00 73.04 C +ATOM 9098 C GLN B 391 -63.319 22.807-119.683 1.00 67.41 C +ATOM 9099 O GLN B 391 -63.170 21.716-120.236 1.00 64.74 O +ATOM 9100 CB GLN B 391 -63.368 24.751-121.222 1.00 77.39 C +ATOM 9101 CG GLN B 391 -62.667 24.029-122.374 1.00 72.87 C +ATOM 9102 CD GLN B 391 -63.626 23.469-123.408 1.00 71.78 C +ATOM 9103 OE1 GLN B 391 -64.678 24.050-123.679 1.00 83.56 O +ATOM 9104 NE2 GLN B 391 -63.258 22.337-124.003 1.00 55.37 N +ATOM 9105 N ARG B 392 -62.729 23.109-118.525 1.00 70.94 N +ATOM 9106 CA ARG B 392 -61.980 22.094-117.795 1.00 62.48 C +ATOM 9107 C ARG B 392 -62.917 21.040-117.235 1.00 57.78 C +ATOM 9108 O ARG B 392 -62.584 19.850-117.213 1.00 58.51 O +ATOM 9109 CB ARG B 392 -61.178 22.735-116.663 1.00 58.08 C +ATOM 9110 CG ARG B 392 -60.666 21.737-115.633 1.00 50.82 C +ATOM 9111 CD ARG B 392 -59.354 21.111-116.056 1.00 51.75 C +ATOM 9112 NE ARG B 392 -58.252 22.056-115.910 1.00 62.25 N +ATOM 9113 CZ ARG B 392 -57.603 22.277-114.771 1.00 67.08 C +ATOM 9114 NH1 ARG B 392 -57.940 21.614-113.672 1.00 60.45 N +ATOM 9115 NH2 ARG B 392 -56.615 23.163-114.729 1.00 69.09 N +ATOM 9116 N LEU B 393 -64.099 21.462-116.788 1.00 60.65 N +ATOM 9117 CA LEU B 393 -65.058 20.515-116.232 1.00 64.62 C +ATOM 9118 C LEU B 393 -65.460 19.467-117.261 1.00 55.87 C +ATOM 9119 O LEU B 393 -65.653 18.296-116.915 1.00 48.05 O +ATOM 9120 CB LEU B 393 -66.291 21.267-115.724 1.00 74.45 C +ATOM 9121 CG LEU B 393 -67.386 20.509-114.973 1.00 62.12 C +ATOM 9122 CD1 LEU B 393 -66.807 19.775-113.774 1.00 58.25 C +ATOM 9123 CD2 LEU B 393 -68.477 21.471-114.546 1.00 59.33 C +ATOM 9124 N LEU B 394 -65.552 19.862-118.531 1.00 56.78 N +ATOM 9125 CA LEU B 394 -65.940 18.917-119.571 1.00 55.47 C +ATOM 9126 C LEU B 394 -64.894 17.827-119.745 1.00 54.51 C +ATOM 9127 O LEU B 394 -65.238 16.658-119.957 1.00 49.67 O +ATOM 9128 CB LEU B 394 -66.169 19.656-120.884 1.00 55.80 C +ATOM 9129 CG LEU B 394 -67.289 20.687-120.847 1.00 53.06 C +ATOM 9130 CD1 LEU B 394 -67.355 21.430-122.160 1.00 59.12 C +ATOM 9131 CD2 LEU B 394 -68.595 19.988-120.549 1.00 49.94 C +ATOM 9132 N ASN B 395 -63.613 18.188-119.654 1.00 59.34 N +ATOM 9133 CA ASN B 395 -62.562 17.182-119.732 1.00 58.15 C +ATOM 9134 C ASN B 395 -62.629 16.215-118.557 1.00 54.60 C +ATOM 9135 O ASN B 395 -62.271 15.040-118.701 1.00 56.33 O +ATOM 9136 CB ASN B 395 -61.189 17.852-119.785 1.00 59.19 C +ATOM 9137 CG ASN B 395 -60.958 18.610-121.071 1.00 62.09 C +ATOM 9138 OD1 ASN B 395 -60.424 18.064-122.037 1.00 64.51 O +ATOM 9139 ND2 ASN B 395 -61.345 19.883-121.087 1.00 65.00 N +ATOM 9140 N VAL B 396 -63.073 16.687-117.389 1.00 49.91 N +ATOM 9141 CA VAL B 396 -63.232 15.785-116.253 1.00 48.92 C +ATOM 9142 C VAL B 396 -64.410 14.851-116.479 1.00 49.87 C +ATOM 9143 O VAL B 396 -64.397 13.699-116.024 1.00 46.59 O +ATOM 9144 CB VAL B 396 -63.391 16.578-114.945 1.00 45.11 C +ATOM 9145 CG1 VAL B 396 -63.384 15.634-113.748 1.00 38.00 C +ATOM 9146 CG2 VAL B 396 -62.294 17.610-114.822 1.00 51.61 C +ATOM 9147 N ILE B 397 -65.443 15.320-117.178 1.00 51.81 N +ATOM 9148 CA ILE B 397 -66.577 14.454-117.483 1.00 53.23 C +ATOM 9149 C ILE B 397 -66.125 13.288-118.355 1.00 48.73 C +ATOM 9150 O ILE B 397 -66.464 12.127-118.098 1.00 44.33 O +ATOM 9151 CB ILE B 397 -67.703 15.257-118.158 1.00 56.45 C +ATOM 9152 CG1 ILE B 397 -68.110 16.462-117.303 1.00 44.07 C +ATOM 9153 CG2 ILE B 397 -68.911 14.361-118.385 1.00 50.24 C +ATOM 9154 CD1 ILE B 397 -68.837 16.104-116.043 1.00 45.02 C +ATOM 9155 N ASP B 398 -65.336 13.580-119.393 1.00 54.62 N +ATOM 9156 CA ASP B 398 -64.816 12.513-120.241 1.00 52.47 C +ATOM 9157 C ASP B 398 -64.014 11.512-119.428 1.00 45.25 C +ATOM 9158 O ASP B 398 -64.212 10.299-119.560 1.00 47.34 O +ATOM 9159 CB ASP B 398 -63.958 13.096-121.364 1.00 56.20 C +ATOM 9160 CG ASP B 398 -64.778 13.846-122.403 1.00 62.72 C +ATOM 9161 OD1 ASP B 398 -65.910 14.285-122.091 1.00 66.65 O +ATOM 9162 OD2 ASP B 398 -64.280 13.997-123.539 1.00 67.26 O +ATOM 9163 N MET B 399 -63.146 12.004-118.538 1.00 44.56 N +ATOM 9164 CA MET B 399 -62.353 11.112-117.699 1.00 44.32 C +ATOM 9165 C MET B 399 -63.244 10.209-116.856 1.00 45.75 C +ATOM 9166 O MET B 399 -62.921 9.036-116.639 1.00 49.13 O +ATOM 9167 CB MET B 399 -61.424 11.923-116.800 1.00 44.18 C +ATOM 9168 CG MET B 399 -60.487 11.077-115.970 1.00 41.18 C +ATOM 9169 SD MET B 399 -59.289 12.065-115.063 1.00 53.11 S +ATOM 9170 CE MET B 399 -60.371 13.123-114.113 1.00 54.77 C +ATOM 9171 N ALA B 400 -64.369 10.737-116.368 1.00 43.78 N +ATOM 9172 CA ALA B 400 -65.306 9.899-115.625 1.00 39.84 C +ATOM 9173 C ALA B 400 -65.901 8.824-116.521 1.00 38.00 C +ATOM 9174 O ALA B 400 -66.063 7.671-116.103 1.00 38.00 O +ATOM 9175 CB ALA B 400 -66.409 10.757-115.008 1.00 41.78 C +ATOM 9176 N ILE B 401 -66.241 9.186-117.757 1.00 41.07 N +ATOM 9177 CA ILE B 401 -66.780 8.207-118.692 1.00 38.47 C +ATOM 9178 C ILE B 401 -65.761 7.109-118.944 1.00 38.00 C +ATOM 9179 O ILE B 401 -66.080 5.915-118.901 1.00 38.09 O +ATOM 9180 CB ILE B 401 -67.200 8.899-119.998 1.00 38.00 C +ATOM 9181 CG1 ILE B 401 -68.310 9.909-119.713 1.00 38.00 C +ATOM 9182 CG2 ILE B 401 -67.658 7.874-121.004 1.00 41.91 C +ATOM 9183 CD1 ILE B 401 -68.730 10.705-120.908 1.00 39.00 C +ATOM 9184 N PHE B 402 -64.511 7.500-119.193 1.00 43.13 N +ATOM 9185 CA PHE B 402 -63.467 6.519-119.466 1.00 46.68 C +ATOM 9186 C PHE B 402 -63.197 5.638-118.249 1.00 42.83 C +ATOM 9187 O PHE B 402 -62.924 4.441-118.396 1.00 46.93 O +ATOM 9188 CB PHE B 402 -62.193 7.232-119.925 1.00 46.96 C +ATOM 9189 CG PHE B 402 -61.046 6.306-120.212 1.00 42.19 C +ATOM 9190 CD1 PHE B 402 -61.122 5.387-121.244 1.00 45.36 C +ATOM 9191 CD2 PHE B 402 -59.889 6.363-119.457 1.00 42.25 C +ATOM 9192 CE1 PHE B 402 -60.068 4.536-121.512 1.00 46.67 C +ATOM 9193 CE2 PHE B 402 -58.831 5.514-119.718 1.00 43.69 C +ATOM 9194 CZ PHE B 402 -58.919 4.601-120.748 1.00 45.12 C +ATOM 9195 N ASP B 403 -63.269 6.202-117.041 1.00 38.00 N +ATOM 9196 CA ASP B 403 -63.036 5.390-115.850 1.00 42.49 C +ATOM 9197 C ASP B 403 -64.228 4.490-115.552 1.00 38.93 C +ATOM 9198 O ASP B 403 -64.055 3.370-115.057 1.00 40.30 O +ATOM 9199 CB ASP B 403 -62.720 6.273-114.647 1.00 45.76 C +ATOM 9200 CG ASP B 403 -61.363 6.928-114.747 1.00 45.74 C +ATOM 9201 OD1 ASP B 403 -60.419 6.303-115.280 1.00 38.00 O +ATOM 9202 OD2 ASP B 403 -61.249 8.078-114.281 1.00 54.02 O +ATOM 9203 N PHE B 404 -65.448 4.973-115.800 1.00 38.00 N +ATOM 9204 CA PHE B 404 -66.612 4.129-115.554 1.00 39.06 C +ATOM 9205 C PHE B 404 -66.646 2.945-116.509 1.00 40.55 C +ATOM 9206 O PHE B 404 -67.004 1.830-116.111 1.00 46.22 O +ATOM 9207 CB PHE B 404 -67.905 4.933-115.679 1.00 39.67 C +ATOM 9208 CG PHE B 404 -69.154 4.092-115.565 1.00 44.01 C +ATOM 9209 CD1 PHE B 404 -69.383 3.310-114.440 1.00 49.56 C +ATOM 9210 CD2 PHE B 404 -70.084 4.063-116.589 1.00 42.32 C +ATOM 9211 CE1 PHE B 404 -70.527 2.528-114.337 1.00 47.57 C +ATOM 9212 CE2 PHE B 404 -71.229 3.283-116.491 1.00 44.01 C +ATOM 9213 CZ PHE B 404 -71.450 2.517-115.363 1.00 42.24 C +ATOM 9214 N LEU B 405 -66.248 3.155-117.764 1.00 38.00 N +ATOM 9215 CA LEU B 405 -66.245 2.053-118.718 1.00 38.00 C +ATOM 9216 C LEU B 405 -65.316 0.936-118.265 1.00 38.00 C +ATOM 9217 O LEU B 405 -65.653 -0.246-118.386 1.00 38.00 O +ATOM 9218 CB LEU B 405 -65.853 2.568-120.097 1.00 38.00 C +ATOM 9219 CG LEU B 405 -66.970 3.349-120.782 1.00 38.00 C +ATOM 9220 CD1 LEU B 405 -66.414 4.069-121.978 1.00 40.97 C +ATOM 9221 CD2 LEU B 405 -68.093 2.417-121.200 1.00 38.00 C +ATOM 9222 N ILE B 406 -64.164 1.289-117.691 1.00 40.50 N +ATOM 9223 CA ILE B 406 -63.211 0.286-117.226 1.00 39.25 C +ATOM 9224 C ILE B 406 -63.358 -0.025-115.743 1.00 38.00 C +ATOM 9225 O ILE B 406 -62.740 -0.990-115.266 1.00 44.40 O +ATOM 9226 CB ILE B 406 -61.753 0.706-117.517 1.00 38.00 C +ATOM 9227 CG1 ILE B 406 -61.382 1.942-116.709 1.00 38.00 C +ATOM 9228 CG2 ILE B 406 -61.557 0.987-118.994 1.00 38.00 C +ATOM 9229 CD1 ILE B 406 -59.991 2.436-117.006 1.00 38.00 C +ATOM 9230 N GLY B 407 -64.142 0.750-115.002 1.00 38.00 N +ATOM 9231 CA GLY B 407 -64.267 0.514-113.574 1.00 39.73 C +ATOM 9232 C GLY B 407 -63.036 0.906-112.785 1.00 39.30 C +ATOM 9233 O GLY B 407 -62.627 0.182-111.866 1.00 38.00 O +ATOM 9234 N ASN B 408 -62.449 2.055-113.104 1.00 38.69 N +ATOM 9235 CA ASN B 408 -61.250 2.545-112.428 1.00 40.40 C +ATOM 9236 C ASN B 408 -61.718 3.544-111.378 1.00 46.44 C +ATOM 9237 O ASN B 408 -61.897 4.731-111.657 1.00 48.85 O +ATOM 9238 CB ASN B 408 -60.272 3.173-113.413 1.00 39.77 C +ATOM 9239 CG ASN B 408 -58.915 3.471-112.785 1.00 39.11 C +ATOM 9240 OD1 ASN B 408 -58.405 2.692-111.977 1.00 38.00 O +ATOM 9241 ND2 ASN B 408 -58.329 4.606-113.151 1.00 40.23 N +ATOM 9242 N MET B 409 -61.950 3.047-110.161 1.00 42.44 N +ATOM 9243 CA MET B 409 -62.339 3.937-109.072 1.00 45.44 C +ATOM 9244 C MET B 409 -61.164 4.777-108.586 1.00 43.18 C +ATOM 9245 O MET B 409 -61.367 5.864-108.036 1.00 51.89 O +ATOM 9246 CB MET B 409 -62.940 3.136-107.919 1.00 48.44 C +ATOM 9247 CG MET B 409 -63.867 2.017-108.361 1.00 49.12 C +ATOM 9248 SD MET B 409 -64.705 1.246-106.962 1.00 44.41 S +ATOM 9249 CE MET B 409 -65.359 -0.240-107.731 1.00 47.70 C +ATOM 9250 N ASP B 410 -59.938 4.303-108.787 1.00 38.75 N +ATOM 9251 CA ASP B 410 -58.745 4.958-108.251 1.00 40.60 C +ATOM 9252 C ASP B 410 -58.219 6.004-109.238 1.00 46.92 C +ATOM 9253 O ASP B 410 -57.182 5.841-109.886 1.00 55.56 O +ATOM 9254 CB ASP B 410 -57.685 3.913-107.931 1.00 40.48 C +ATOM 9255 CG ASP B 410 -56.473 4.496-107.242 1.00 46.96 C +ATOM 9256 OD1 ASP B 410 -56.445 5.724-107.026 1.00 52.11 O +ATOM 9257 OD2 ASP B 410 -55.537 3.727-106.932 1.00 49.44 O +ATOM 9258 N ARG B 411 -58.943 7.116-109.318 1.00 43.72 N +ATOM 9259 CA ARG B 411 -58.509 8.287-110.078 1.00 45.23 C +ATOM 9260 C ARG B 411 -58.497 9.495-109.142 1.00 47.19 C +ATOM 9261 O ARG B 411 -59.323 10.406-109.259 1.00 43.66 O +ATOM 9262 CB ARG B 411 -59.401 8.522-111.310 1.00 42.17 C +ATOM 9263 CG ARG B 411 -58.876 9.624-112.248 1.00 49.42 C +ATOM 9264 CD ARG B 411 -58.476 9.087-113.618 1.00 47.13 C +ATOM 9265 NE ARG B 411 -57.217 8.352-113.625 1.00 46.82 N +ATOM 9266 CZ ARG B 411 -56.793 7.627-114.655 1.00 45.56 C +ATOM 9267 NH1 ARG B 411 -57.535 7.531-115.752 1.00 38.00 N +ATOM 9268 NH2 ARG B 411 -55.632 6.991-114.588 1.00 50.37 N +ATOM 9269 N HIS B 412 -57.548 9.492-108.200 1.00 45.10 N +ATOM 9270 CA HIS B 412 -57.434 10.597-107.254 1.00 45.10 C +ATOM 9271 C HIS B 412 -56.836 11.847-107.896 1.00 46.21 C +ATOM 9272 O HIS B 412 -57.182 12.968-107.504 1.00 47.38 O +ATOM 9273 CB HIS B 412 -56.617 10.172-106.030 1.00 44.52 C +ATOM 9274 CG HIS B 412 -55.327 9.477-106.347 1.00 47.58 C +ATOM 9275 ND1 HIS B 412 -54.753 9.483-107.599 1.00 50.24 N +ATOM 9276 CD2 HIS B 412 -54.498 8.752-105.558 1.00 50.43 C +ATOM 9277 CE1 HIS B 412 -53.628 8.791-107.570 1.00 51.12 C +ATOM 9278 NE2 HIS B 412 -53.451 8.335-106.343 1.00 52.44 N +ATOM 9279 N HIS B 413 -55.945 11.687-108.868 1.00 46.17 N +ATOM 9280 CA HIS B 413 -55.281 12.819-109.494 1.00 47.09 C +ATOM 9281 C HIS B 413 -55.223 12.617-110.999 1.00 48.70 C +ATOM 9282 O HIS B 413 -55.043 11.494-111.484 1.00 47.44 O +ATOM 9283 CB HIS B 413 -53.859 13.023-108.947 1.00 50.23 C +ATOM 9284 CG HIS B 413 -53.810 13.446-107.510 1.00 47.25 C +ATOM 9285 ND1 HIS B 413 -54.090 12.588-106.468 1.00 46.41 N +ATOM 9286 CD2 HIS B 413 -53.489 14.634-106.943 1.00 44.80 C +ATOM 9287 CE1 HIS B 413 -53.959 13.233-105.322 1.00 46.72 C +ATOM 9288 NE2 HIS B 413 -53.595 14.476-105.582 1.00 47.78 N +ATOM 9289 N TYR B 414 -55.398 13.712-111.729 1.00 48.64 N +ATOM 9290 CA TYR B 414 -55.213 13.741-113.170 1.00 50.62 C +ATOM 9291 C TYR B 414 -54.126 14.756-113.502 1.00 50.57 C +ATOM 9292 O TYR B 414 -54.080 15.839-112.911 1.00 50.61 O +ATOM 9293 CB TYR B 414 -56.527 14.083-113.892 1.00 49.47 C +ATOM 9294 CG TYR B 414 -57.097 15.455-113.594 1.00 48.98 C +ATOM 9295 CD1 TYR B 414 -57.956 15.666-112.523 1.00 48.42 C +ATOM 9296 CD2 TYR B 414 -56.792 16.538-114.407 1.00 52.84 C +ATOM 9297 CE1 TYR B 414 -58.480 16.927-112.262 1.00 52.63 C +ATOM 9298 CE2 TYR B 414 -57.309 17.794-114.157 1.00 54.22 C +ATOM 9299 CZ TYR B 414 -58.152 17.986-113.088 1.00 54.33 C +ATOM 9300 OH TYR B 414 -58.660 19.245-112.854 1.00 51.90 O +ATOM 9301 N GLU B 415 -53.227 14.390-114.414 1.00 48.68 N +ATOM 9302 CA GLU B 415 -52.106 15.244-114.783 1.00 49.81 C +ATOM 9303 C GLU B 415 -52.415 16.027-116.052 1.00 46.73 C +ATOM 9304 O GLU B 415 -53.187 15.581-116.905 1.00 46.79 O +ATOM 9305 CB GLU B 415 -50.829 14.422-114.977 1.00 52.95 C +ATOM 9306 CG GLU B 415 -50.279 13.819-113.693 1.00 56.70 C +ATOM 9307 CD GLU B 415 -48.884 13.251-113.861 1.00 51.44 C +ATOM 9308 OE1 GLU B 415 -48.252 13.511-114.906 1.00 48.52 O +ATOM 9309 OE2 GLU B 415 -48.415 12.545-112.945 1.00 54.47 O +ATOM 9310 N MET B 416 -51.784 17.196-116.177 1.00 52.96 N +ATOM 9311 CA MET B 416 -51.980 18.080-117.319 1.00 55.25 C +ATOM 9312 C MET B 416 -50.641 18.633-117.786 1.00 52.83 C +ATOM 9313 O MET B 416 -49.692 18.748-117.004 1.00 51.72 O +ATOM 9314 CB MET B 416 -52.912 19.256-116.990 1.00 54.24 C +ATOM 9315 CG MET B 416 -54.261 18.857-116.433 1.00 54.16 C +ATOM 9316 SD MET B 416 -55.335 20.282-116.188 1.00 58.55 S +ATOM 9317 CE MET B 416 -55.184 21.094-117.778 1.00 57.23 C +ATOM 9318 N PHE B 417 -50.579 18.993-119.068 1.00 51.68 N +ATOM 9319 CA PHE B 417 -49.417 19.672-119.627 1.00 50.45 C +ATOM 9320 C PHE B 417 -49.571 21.165-119.381 1.00 50.95 C +ATOM 9321 O PHE B 417 -50.553 21.774-119.820 1.00 51.37 O +ATOM 9322 CB PHE B 417 -49.266 19.395-121.123 1.00 46.78 C +ATOM 9323 CG PHE B 417 -48.805 18.004-121.442 1.00 44.02 C +ATOM 9324 CD1 PHE B 417 -47.531 17.588-121.095 1.00 48.94 C +ATOM 9325 CD2 PHE B 417 -49.638 17.117-122.104 1.00 45.41 C +ATOM 9326 CE1 PHE B 417 -47.101 16.306-121.390 1.00 52.63 C +ATOM 9327 CE2 PHE B 417 -49.214 15.835-122.405 1.00 43.34 C +ATOM 9328 CZ PHE B 417 -47.944 15.428-122.048 1.00 47.12 C +ATOM 9329 N THR B 418 -48.599 21.749-118.682 1.00 48.88 N +ATOM 9330 CA THR B 418 -48.718 23.143-118.286 1.00 53.92 C +ATOM 9331 C THR B 418 -48.712 24.085-119.485 1.00 55.67 C +ATOM 9332 O THR B 418 -49.252 25.192-119.391 1.00 58.28 O +ATOM 9333 CB THR B 418 -47.598 23.499-117.310 1.00 47.52 C +ATOM 9334 OG1 THR B 418 -47.624 24.903-117.046 1.00 57.44 O +ATOM 9335 CG2 THR B 418 -46.257 23.142-117.904 1.00 47.53 C +ATOM 9336 N LYS B 419 -48.125 23.667-120.609 1.00 49.55 N +ATOM 9337 CA LYS B 419 -48.091 24.525-121.787 1.00 50.83 C +ATOM 9338 C LYS B 419 -49.483 24.733-122.369 1.00 57.55 C +ATOM 9339 O LYS B 419 -49.758 25.786-122.958 1.00 60.70 O +ATOM 9340 CB LYS B 419 -47.151 23.931-122.839 1.00 51.29 C +ATOM 9341 CG LYS B 419 -47.059 24.728-124.130 1.00 57.62 C +ATOM 9342 CD LYS B 419 -45.928 24.224-125.014 1.00 60.52 C +ATOM 9343 CE LYS B 419 -45.860 24.998-126.321 1.00 62.52 C +ATOM 9344 NZ LYS B 419 -44.694 24.602-127.151 1.00 54.03 N +ATOM 9345 N PHE B 420 -50.378 23.762-122.194 1.00 55.91 N +ATOM 9346 CA PHE B 420 -51.685 23.804-122.831 1.00 60.04 C +ATOM 9347 C PHE B 420 -52.731 24.555-122.021 1.00 63.27 C +ATOM 9348 O PHE B 420 -53.831 24.794-122.534 1.00 71.66 O +ATOM 9349 CB PHE B 420 -52.178 22.386-123.121 1.00 59.01 C +ATOM 9350 CG PHE B 420 -51.321 21.645-124.105 1.00 56.07 C +ATOM 9351 CD1 PHE B 420 -50.661 22.325-125.115 1.00 53.01 C +ATOM 9352 CD2 PHE B 420 -51.194 20.270-124.036 1.00 54.34 C +ATOM 9353 CE1 PHE B 420 -49.881 21.649-126.026 1.00 55.34 C +ATOM 9354 CE2 PHE B 420 -50.414 19.587-124.948 1.00 52.72 C +ATOM 9355 CZ PHE B 420 -49.760 20.278-125.945 1.00 55.23 C +ATOM 9356 N GLY B 421 -52.441 24.898-120.773 1.00 52.90 N +ATOM 9357 CA GLY B 421 -53.322 25.775-120.039 1.00 57.18 C +ATOM 9358 C GLY B 421 -54.520 25.049-119.460 1.00 65.00 C +ATOM 9359 O GLY B 421 -54.637 23.820-119.507 1.00 66.91 O +ATOM 9360 N ASP B 422 -55.447 25.852-118.928 1.00 62.91 N +ATOM 9361 CA ASP B 422 -56.624 25.304-118.262 1.00 64.23 C +ATOM 9362 C ASP B 422 -57.498 24.504-119.216 1.00 69.47 C +ATOM 9363 O ASP B 422 -58.186 23.568-118.791 1.00 70.18 O +ATOM 9364 CB ASP B 422 -57.436 26.433-117.639 1.00 61.01 C +ATOM 9365 CG ASP B 422 -56.572 27.407-116.885 1.00 72.38 C +ATOM 9366 OD1 ASP B 422 -55.869 28.206-117.542 1.00 71.12 O +ATOM 9367 OD2 ASP B 422 -56.580 27.361-115.640 1.00 84.71 O +ATOM 9368 N ASP B 423 -57.492 24.851-120.497 1.00 68.09 N +ATOM 9369 CA ASP B 423 -58.282 24.120-121.473 1.00 69.95 C +ATOM 9370 C ASP B 423 -57.553 22.907-122.030 1.00 66.44 C +ATOM 9371 O ASP B 423 -58.121 22.195-122.863 1.00 69.31 O +ATOM 9372 CB ASP B 423 -58.706 25.050-122.614 1.00 74.86 C +ATOM 9373 CG ASP B 423 -59.670 26.134-122.156 1.00 84.95 C +ATOM 9374 OD1 ASP B 423 -60.349 25.938-121.122 1.00 84.89 O +ATOM 9375 OD2 ASP B 423 -59.741 27.188-122.825 1.00 81.64 O +ATOM 9376 N GLY B 424 -56.326 22.647-121.582 1.00 62.36 N +ATOM 9377 CA GLY B 424 -55.600 21.491-122.068 1.00 61.16 C +ATOM 9378 C GLY B 424 -56.273 20.192-121.669 1.00 62.78 C +ATOM 9379 O GLY B 424 -57.019 20.121-120.692 1.00 66.49 O +ATOM 9380 N PHE B 425 -56.018 19.152-122.456 1.00 57.40 N +ATOM 9381 CA PHE B 425 -56.600 17.846-122.190 1.00 54.77 C +ATOM 9382 C PHE B 425 -55.940 17.186-120.981 1.00 54.08 C +ATOM 9383 O PHE B 425 -54.856 17.574-120.532 1.00 47.53 O +ATOM 9384 CB PHE B 425 -56.473 16.944-123.416 1.00 54.87 C +ATOM 9385 CG PHE B 425 -55.056 16.625-123.782 1.00 51.31 C +ATOM 9386 CD1 PHE B 425 -54.300 17.531-124.501 1.00 51.28 C +ATOM 9387 CD2 PHE B 425 -54.481 15.424-123.409 1.00 47.84 C +ATOM 9388 CE1 PHE B 425 -52.998 17.248-124.841 1.00 50.98 C +ATOM 9389 CE2 PHE B 425 -53.179 15.136-123.745 1.00 48.39 C +ATOM 9390 CZ PHE B 425 -52.435 16.050-124.463 1.00 47.97 C +ATOM 9391 N LEU B 426 -56.610 16.163-120.461 1.00 55.31 N +ATOM 9392 CA LEU B 426 -56.148 15.438-119.285 1.00 57.00 C +ATOM 9393 C LEU B 426 -55.475 14.134-119.691 1.00 56.67 C +ATOM 9394 O LEU B 426 -55.917 13.454-120.623 1.00 61.16 O +ATOM 9395 CB LEU B 426 -57.309 15.136-118.335 1.00 57.75 C +ATOM 9396 CG LEU B 426 -58.270 16.283-118.035 1.00 55.78 C +ATOM 9397 CD1 LEU B 426 -59.251 15.889-116.943 1.00 48.21 C +ATOM 9398 CD2 LEU B 426 -57.492 17.528-117.646 1.00 55.06 C +ATOM 9399 N ILE B 427 -54.415 13.782-118.976 1.00 50.22 N +ATOM 9400 CA ILE B 427 -53.685 12.550-119.231 1.00 45.12 C +ATOM 9401 C ILE B 427 -54.220 11.473-118.304 1.00 45.44 C +ATOM 9402 O ILE B 427 -54.289 11.668-117.086 1.00 48.61 O +ATOM 9403 CB ILE B 427 -52.178 12.750-119.021 1.00 42.68 C +ATOM 9404 CG1 ILE B 427 -51.779 14.172-119.395 1.00 43.57 C +ATOM 9405 CG2 ILE B 427 -51.400 11.753-119.853 1.00 42.86 C +ATOM 9406 CD1 ILE B 427 -50.336 14.465-119.114 1.00 45.54 C +ATOM 9407 N HIS B 428 -54.582 10.328-118.875 1.00 39.78 N +ATOM 9408 CA HIS B 428 -55.107 9.210-118.100 1.00 38.83 C +ATOM 9409 C HIS B 428 -53.978 8.199-117.931 1.00 38.53 C +ATOM 9410 O HIS B 428 -53.854 7.230-118.677 1.00 46.93 O +ATOM 9411 CB HIS B 428 -56.328 8.607-118.787 1.00 43.03 C +ATOM 9412 CG HIS B 428 -57.374 9.610-119.172 1.00 43.89 C +ATOM 9413 ND1 HIS B 428 -58.378 9.328-120.075 1.00 43.46 N +ATOM 9414 CD2 HIS B 428 -57.588 10.883-118.760 1.00 43.82 C +ATOM 9415 CE1 HIS B 428 -59.157 10.385-120.210 1.00 45.38 C +ATOM 9416 NE2 HIS B 428 -58.701 11.342-119.422 1.00 45.86 N +ATOM 9417 N LEU B 429 -53.135 8.442-116.927 1.00 38.00 N +ATOM 9418 CA LEU B 429 -51.860 7.730-116.827 1.00 43.66 C +ATOM 9419 C LEU B 429 -52.004 6.307-116.294 1.00 46.50 C +ATOM 9420 O LEU B 429 -51.722 5.335-117.002 1.00 51.70 O +ATOM 9421 CB LEU B 429 -50.880 8.524-115.962 1.00 47.92 C +ATOM 9422 CG LEU B 429 -50.124 9.611-116.719 1.00 47.27 C +ATOM 9423 CD1 LEU B 429 -49.068 10.256-115.831 1.00 50.58 C +ATOM 9424 CD2 LEU B 429 -49.499 9.029-117.976 1.00 46.13 C +ATOM 9425 N ASP B 430 -52.412 6.162-115.038 1.00 42.95 N +ATOM 9426 CA ASP B 430 -52.378 4.866-114.362 1.00 53.38 C +ATOM 9427 C ASP B 430 -53.782 4.273-114.347 1.00 48.47 C +ATOM 9428 O ASP B 430 -54.607 4.617-113.497 1.00 46.49 O +ATOM 9429 CB ASP B 430 -51.814 5.008-112.951 1.00 74.80 C +ATOM 9430 CG ASP B 430 -50.300 5.237-112.937 1.00 84.53 C +ATOM 9431 OD1 ASP B 430 -49.560 4.352-113.423 1.00 83.29 O +ATOM 9432 OD2 ASP B 430 -49.848 6.290-112.426 1.00110.10 O +ATOM 9433 N ASN B 431 -54.040 3.354-115.277 1.00 43.89 N +ATOM 9434 CA ASN B 431 -55.328 2.684-115.391 1.00 38.00 C +ATOM 9435 C ASN B 431 -55.249 1.231-114.963 1.00 39.62 C +ATOM 9436 O ASN B 431 -56.169 0.458-115.250 1.00 38.00 O +ATOM 9437 CB ASN B 431 -55.847 2.760-116.824 1.00 38.00 C +ATOM 9438 CG ASN B 431 -55.539 4.074-117.483 1.00 39.85 C +ATOM 9439 OD1 ASN B 431 -56.104 5.106-117.123 1.00 39.28 O +ATOM 9440 ND2 ASN B 431 -54.640 4.048-118.465 1.00 39.31 N +ATOM 9441 N ALA B 432 -54.170 0.841-114.283 1.00 45.21 N +ATOM 9442 CA ALA B 432 -53.915 -0.561-113.981 1.00 49.25 C +ATOM 9443 C ALA B 432 -54.949 -1.173-113.051 1.00 38.33 C +ATOM 9444 O ALA B 432 -54.890 -2.381-112.802 1.00 38.00 O +ATOM 9445 CB ALA B 432 -52.522 -0.719-113.372 1.00 50.93 C +ATOM 9446 N ARG B 433 -55.881 -0.385-112.528 1.00 38.00 N +ATOM 9447 CA ARG B 433 -56.852 -0.895-111.574 1.00 38.00 C +ATOM 9448 C ARG B 433 -58.185 -1.252-112.203 1.00 38.00 C +ATOM 9449 O ARG B 433 -58.899 -2.107-111.671 1.00 39.10 O +ATOM 9450 CB ARG B 433 -57.062 0.124-110.454 1.00 38.00 C +ATOM 9451 CG ARG B 433 -55.811 0.346-109.647 1.00 38.00 C +ATOM 9452 CD ARG B 433 -56.131 0.451-108.190 1.00 38.00 C +ATOM 9453 NE ARG B 433 -54.977 0.877-107.416 1.00 38.00 N +ATOM 9454 CZ ARG B 433 -54.682 0.390-106.219 1.00 38.36 C +ATOM 9455 NH1 ARG B 433 -55.451 -0.546-105.683 1.00 38.00 N +ATOM 9456 NH2 ARG B 433 -53.616 0.823-105.563 1.00 43.46 N +ATOM 9457 N GLY B 434 -58.538 -0.628-113.319 1.00 38.00 N +ATOM 9458 CA GLY B 434 -59.766 -0.953-114.026 1.00 38.00 C +ATOM 9459 C GLY B 434 -59.822 -2.385-114.517 1.00 38.00 C +ATOM 9460 O GLY B 434 -58.850 -3.128-114.362 1.00 38.00 O +ATOM 9461 N PHE B 435 -60.954 -2.793-115.091 1.00 38.00 N +ATOM 9462 CA PHE B 435 -61.123 -4.147-115.623 1.00 38.19 C +ATOM 9463 C PHE B 435 -60.857 -5.199-114.554 1.00 42.40 C +ATOM 9464 O PHE B 435 -60.050 -6.110-114.739 1.00 44.57 O +ATOM 9465 CB PHE B 435 -60.226 -4.357-116.837 1.00 38.00 C +ATOM 9466 CG PHE B 435 -60.746 -3.696-118.051 1.00 38.00 C +ATOM 9467 CD1 PHE B 435 -62.038 -3.933-118.470 1.00 38.00 C +ATOM 9468 CD2 PHE B 435 -59.968 -2.799-118.750 1.00 38.00 C +ATOM 9469 CE1 PHE B 435 -62.537 -3.312-119.583 1.00 38.05 C +ATOM 9470 CE2 PHE B 435 -60.464 -2.170-119.867 1.00 38.00 C +ATOM 9471 CZ PHE B 435 -61.750 -2.425-120.284 1.00 38.00 C +ATOM 9472 N GLY B 436 -61.531 -5.055-113.418 1.00 42.62 N +ATOM 9473 CA GLY B 436 -61.409 -6.031-112.357 1.00 47.35 C +ATOM 9474 C GLY B 436 -62.736 -6.653-111.976 1.00 48.14 C +ATOM 9475 O GLY B 436 -62.777 -7.744-111.405 1.00 48.51 O +ATOM 9476 N ARG B 437 -63.833 -5.988-112.316 1.00 45.57 N +ATOM 9477 CA ARG B 437 -65.172 -6.475-111.998 1.00 52.60 C +ATOM 9478 C ARG B 437 -65.952 -6.478-113.307 1.00 55.08 C +ATOM 9479 O ARG B 437 -66.377 -5.425-113.790 1.00 55.51 O +ATOM 9480 CB ARG B 437 -65.856 -5.609-110.935 1.00 65.12 C +ATOM 9481 CG ARG B 437 -65.217 -5.629-109.538 1.00 60.61 C +ATOM 9482 CD ARG B 437 -65.433 -6.961-108.814 1.00 73.06 C +ATOM 9483 NE ARG B 437 -66.847 -7.287-108.605 1.00 81.32 N +ATOM 9484 CZ ARG B 437 -67.559 -6.919-107.541 1.00 76.45 C +ATOM 9485 NH1 ARG B 437 -66.998 -6.208-106.572 1.00 72.70 N +ATOM 9486 NH2 ARG B 437 -68.837 -7.267-107.442 1.00 71.17 N +ATOM 9487 N HIS B 438 -66.090 -7.653-113.912 1.00 55.44 N +ATOM 9488 CA HIS B 438 -66.907 -7.747-115.112 1.00 57.04 C +ATOM 9489 C HIS B 438 -68.384 -7.916-114.793 1.00 58.64 C +ATOM 9490 O HIS B 438 -69.228 -7.702-115.671 1.00 57.20 O +ATOM 9491 CB HIS B 438 -66.438 -8.912-115.981 1.00 57.44 C +ATOM 9492 CG HIS B 438 -66.543 -10.244-115.309 1.00 52.47 C +ATOM 9493 ND1 HIS B 438 -67.751 -10.853-115.046 1.00 48.54 N +ATOM 9494 CD2 HIS B 438 -65.589 -11.093-114.860 1.00 53.95 C +ATOM 9495 CE1 HIS B 438 -67.537 -12.014-114.455 1.00 55.77 C +ATOM 9496 NE2 HIS B 438 -66.234 -12.184-114.331 1.00 57.48 N +ATOM 9497 N SER B 439 -68.713 -8.282-113.556 1.00 57.05 N +ATOM 9498 CA SER B 439 -70.091 -8.491-113.147 1.00 52.52 C +ATOM 9499 C SER B 439 -70.673 -7.311-112.383 1.00 47.60 C +ATOM 9500 O SER B 439 -71.872 -7.317-112.092 1.00 54.56 O +ATOM 9501 CB SER B 439 -70.193 -9.761-112.294 1.00 52.90 C +ATOM 9502 OG SER B 439 -71.498 -9.922-111.774 1.00 65.85 O +ATOM 9503 N HIS B 440 -69.870 -6.303-112.068 1.00 41.64 N +ATOM 9504 CA HIS B 440 -70.311 -5.172-111.267 1.00 47.79 C +ATOM 9505 C HIS B 440 -70.015 -3.879-112.011 1.00 48.03 C +ATOM 9506 O HIS B 440 -68.981 -3.761-112.673 1.00 52.45 O +ATOM 9507 CB HIS B 440 -69.605 -5.192-109.904 1.00 56.25 C +ATOM 9508 CG HIS B 440 -69.996 -4.074-108.990 1.00 56.05 C +ATOM 9509 ND1 HIS B 440 -71.295 -3.869-108.576 1.00 54.05 N +ATOM 9510 CD2 HIS B 440 -69.253 -3.110-108.394 1.00 50.79 C +ATOM 9511 CE1 HIS B 440 -71.337 -2.823-107.771 1.00 56.12 C +ATOM 9512 NE2 HIS B 440 -70.112 -2.343-107.646 1.00 56.00 N +ATOM 9513 N ASP B 441 -70.934 -2.919-111.927 1.00 47.12 N +ATOM 9514 CA ASP B 441 -70.734 -1.591-112.500 1.00 46.36 C +ATOM 9515 C ASP B 441 -70.781 -0.568-111.376 1.00 47.46 C +ATOM 9516 O ASP B 441 -71.799 -0.450-110.685 1.00 45.77 O +ATOM 9517 CB ASP B 441 -71.791 -1.274-113.557 1.00 47.36 C +ATOM 9518 CG ASP B 441 -71.844 -2.311-114.658 1.00 49.46 C +ATOM 9519 OD1 ASP B 441 -70.861 -3.064-114.830 1.00 52.22 O +ATOM 9520 OD2 ASP B 441 -72.872 -2.364-115.362 1.00 47.47 O +ATOM 9521 N GLU B 442 -69.686 0.170-111.191 1.00 50.75 N +ATOM 9522 CA GLU B 442 -69.587 1.139-110.099 1.00 49.62 C +ATOM 9523 C GLU B 442 -70.051 2.492-110.615 1.00 43.08 C +ATOM 9524 O GLU B 442 -69.285 3.228-111.243 1.00 39.22 O +ATOM 9525 CB GLU B 442 -68.163 1.212-109.565 1.00 57.29 C +ATOM 9526 CG GLU B 442 -68.044 2.002-108.270 1.00 63.74 C +ATOM 9527 CD GLU B 442 -68.885 1.419-107.139 1.00 65.60 C +ATOM 9528 OE1 GLU B 442 -69.824 2.104-106.676 1.00 68.11 O +ATOM 9529 OE2 GLU B 442 -68.625 0.262-106.735 1.00 57.87 O +ATOM 9530 N ILE B 443 -71.299 2.843-110.303 1.00 43.16 N +ATOM 9531 CA ILE B 443 -71.885 4.057-110.854 1.00 45.33 C +ATOM 9532 C ILE B 443 -71.366 5.312-110.172 1.00 46.35 C +ATOM 9533 O ILE B 443 -71.519 6.410-110.722 1.00 44.29 O +ATOM 9534 CB ILE B 443 -73.419 4.030-110.774 1.00 41.29 C +ATOM 9535 CG1 ILE B 443 -73.938 2.588-110.711 1.00 40.72 C +ATOM 9536 CG2 ILE B 443 -74.013 4.776-111.963 1.00 38.00 C +ATOM 9537 CD1 ILE B 443 -74.175 2.066-109.292 1.00 41.28 C +ATOM 9538 N SER B 444 -70.765 5.187-108.986 1.00 44.28 N +ATOM 9539 CA SER B 444 -70.196 6.359-108.334 1.00 45.99 C +ATOM 9540 C SER B 444 -69.080 6.973-109.163 1.00 47.22 C +ATOM 9541 O SER B 444 -68.789 8.164-109.012 1.00 48.20 O +ATOM 9542 CB SER B 444 -69.679 6.001-106.940 1.00 41.60 C +ATOM 9543 OG SER B 444 -68.738 4.948-107.005 1.00 42.98 O +ATOM 9544 N ILE B 445 -68.453 6.187-110.039 1.00 47.51 N +ATOM 9545 CA ILE B 445 -67.446 6.742-110.933 1.00 42.63 C +ATOM 9546 C ILE B 445 -68.084 7.758-111.863 1.00 43.39 C +ATOM 9547 O ILE B 445 -67.487 8.792-112.186 1.00 42.35 O +ATOM 9548 CB ILE B 445 -66.763 5.610-111.717 1.00 40.99 C +ATOM 9549 CG1 ILE B 445 -66.349 4.498-110.755 1.00 42.99 C +ATOM 9550 CG2 ILE B 445 -65.552 6.148-112.448 1.00 43.41 C +ATOM 9551 CD1 ILE B 445 -65.839 3.257-111.427 1.00 40.95 C +ATOM 9552 N LEU B 446 -69.324 7.496-112.274 1.00 48.58 N +ATOM 9553 CA LEU B 446 -70.085 8.344-113.181 1.00 52.25 C +ATOM 9554 C LEU B 446 -70.684 9.565-112.492 1.00 49.94 C +ATOM 9555 O LEU B 446 -71.433 10.313-113.131 1.00 47.73 O +ATOM 9556 CB LEU B 446 -71.197 7.521-113.844 1.00 48.10 C +ATOM 9557 CG LEU B 446 -71.335 7.540-115.370 1.00 42.68 C +ATOM 9558 CD1 LEU B 446 -72.312 8.607-115.822 1.00 46.80 C +ATOM 9559 CD2 LEU B 446 -69.990 7.749-116.030 1.00 41.06 C +ATOM 9560 N SER B 447 -70.356 9.786-111.222 1.00 50.48 N +ATOM 9561 CA SER B 447 -70.906 10.924-110.489 1.00 52.72 C +ATOM 9562 C SER B 447 -70.703 12.273-111.173 1.00 53.20 C +ATOM 9563 O SER B 447 -71.623 13.104-111.099 1.00 60.26 O +ATOM 9564 CB SER B 447 -70.321 10.951-109.070 1.00 49.75 C +ATOM 9565 OG SER B 447 -70.858 9.895-108.292 1.00 50.32 O +ATOM 9566 N PRO B 448 -69.568 12.575-111.822 1.00 45.24 N +ATOM 9567 CA PRO B 448 -69.480 13.873-112.515 1.00 42.29 C +ATOM 9568 C PRO B 448 -70.569 14.068-113.556 1.00 44.95 C +ATOM 9569 O PRO B 448 -71.233 15.112-113.570 1.00 45.91 O +ATOM 9570 CB PRO B 448 -68.080 13.834-113.140 1.00 39.72 C +ATOM 9571 CG PRO B 448 -67.310 12.950-112.261 1.00 44.65 C +ATOM 9572 CD PRO B 448 -68.269 11.879-111.830 1.00 45.48 C +ATOM 9573 N LEU B 449 -70.784 13.081-114.426 1.00 40.93 N +ATOM 9574 CA LEU B 449 -71.844 13.205-115.417 1.00 41.29 C +ATOM 9575 C LEU B 449 -73.219 13.137-114.773 1.00 45.52 C +ATOM 9576 O LEU B 449 -74.152 13.806-115.234 1.00 50.93 O +ATOM 9577 CB LEU B 449 -71.703 12.120-116.477 1.00 38.00 C +ATOM 9578 CG LEU B 449 -72.654 12.230-117.664 1.00 38.00 C +ATOM 9579 CD1 LEU B 449 -72.425 13.531-118.423 1.00 38.00 C +ATOM 9580 CD2 LEU B 449 -72.476 11.036-118.568 1.00 42.85 C +ATOM 9581 N SER B 450 -73.364 12.344-113.709 1.00 47.79 N +ATOM 9582 CA SER B 450 -74.659 12.226-113.050 1.00 49.34 C +ATOM 9583 C SER B 450 -75.100 13.560-112.464 1.00 52.47 C +ATOM 9584 O SER B 450 -76.246 13.984-112.657 1.00 56.87 O +ATOM 9585 CB SER B 450 -74.594 11.165-111.947 1.00 46.88 C +ATOM 9586 OG SER B 450 -74.155 9.912-112.442 1.00 46.51 O +ATOM 9587 N GLN B 451 -74.186 14.263-111.796 1.00 49.31 N +ATOM 9588 CA GLN B 451 -74.532 15.449-111.025 1.00 49.93 C +ATOM 9589 C GLN B 451 -74.410 16.731-111.838 1.00 55.70 C +ATOM 9590 O GLN B 451 -75.289 17.595-111.758 1.00 64.43 O +ATOM 9591 CB GLN B 451 -73.643 15.532-109.779 1.00 53.69 C +ATOM 9592 CG GLN B 451 -73.632 14.242-108.951 1.00 57.93 C +ATOM 9593 CD GLN B 451 -72.609 14.254-107.822 1.00 52.52 C +ATOM 9594 OE1 GLN B 451 -71.487 14.741-107.984 1.00 48.02 O +ATOM 9595 NE2 GLN B 451 -72.983 13.681-106.682 1.00 50.39 N +ATOM 9596 N CYS B 452 -73.346 16.868-112.634 1.00 53.95 N +ATOM 9597 CA CYS B 452 -73.185 18.070-113.448 1.00 55.42 C +ATOM 9598 C CYS B 452 -74.184 18.104-114.588 1.00 60.74 C +ATOM 9599 O CYS B 452 -74.677 19.175-114.961 1.00 65.95 O +ATOM 9600 CB CYS B 452 -71.769 18.145-113.998 1.00 52.04 C +ATOM 9601 SG CYS B 452 -70.542 18.162-112.714 1.00 66.10 S +ATOM 9602 N CYS B 453 -74.464 16.943-115.168 1.00 56.80 N +ATOM 9603 CA CYS B 453 -75.404 16.803-116.269 1.00 57.33 C +ATOM 9604 C CYS B 453 -75.042 17.755-117.415 1.00 58.20 C +ATOM 9605 O CYS B 453 -75.730 18.732-117.714 1.00 57.28 O +ATOM 9606 CB CYS B 453 -76.834 17.019-115.776 1.00 57.38 C +ATOM 9607 SG CYS B 453 -78.031 16.718-117.071 1.00 97.46 S +ATOM 9608 N MET B 454 -73.907 17.433-118.032 1.00 54.27 N +ATOM 9609 CA MET B 454 -73.455 18.059-119.268 1.00 54.57 C +ATOM 9610 C MET B 454 -72.321 17.232-119.854 1.00 47.92 C +ATOM 9611 O MET B 454 -71.442 16.776-119.119 1.00 46.16 O +ATOM 9612 CB MET B 454 -73.028 19.510-119.035 1.00 56.04 C +ATOM 9613 CG MET B 454 -72.148 19.734-117.835 1.00 55.06 C +ATOM 9614 SD MET B 454 -72.037 21.496-117.488 1.00 57.55 S +ATOM 9615 CE MET B 454 -71.757 22.151-119.132 1.00 46.85 C +ATOM 9616 N ILE B 455 -72.365 16.999-121.166 1.00 47.97 N +ATOM 9617 CA ILE B 455 -71.411 16.150-121.869 1.00 48.37 C +ATOM 9618 C ILE B 455 -70.996 16.851-123.155 1.00 55.99 C +ATOM 9619 O ILE B 455 -71.779 17.595-123.753 1.00 64.73 O +ATOM 9620 CB ILE B 455 -72.013 14.757-122.173 1.00 45.59 C +ATOM 9621 CG1 ILE B 455 -70.989 13.834-122.819 1.00 49.88 C +ATOM 9622 CG2 ILE B 455 -73.200 14.864-123.098 1.00 46.32 C +ATOM 9623 CD1 ILE B 455 -71.567 12.481-123.176 1.00 46.11 C +ATOM 9624 N LYS B 456 -69.756 16.614-123.586 1.00 58.66 N +ATOM 9625 CA LYS B 456 -69.268 17.241-124.808 1.00 64.47 C +ATOM 9626 C LYS B 456 -69.970 16.670-126.038 1.00 57.15 C +ATOM 9627 O LYS B 456 -70.338 15.492-126.089 1.00 49.29 O +ATOM 9628 CB LYS B 456 -67.750 17.079-124.933 1.00 55.66 C +ATOM 9629 CG LYS B 456 -67.013 17.422-123.649 1.00 65.07 C +ATOM 9630 CD LYS B 456 -65.579 17.931-123.872 1.00 75.68 C +ATOM 9631 CE LYS B 456 -64.672 16.910-124.538 1.00 69.94 C +ATOM 9632 NZ LYS B 456 -63.235 17.321-124.464 1.00 50.56 N +ATOM 9633 N LYS B 457 -70.171 17.538-127.033 1.00 58.76 N +ATOM 9634 CA LYS B 457 -70.845 17.127-128.261 1.00 55.18 C +ATOM 9635 C LYS B 457 -70.090 15.993-128.943 1.00 52.43 C +ATOM 9636 O LYS B 457 -70.672 14.951-129.265 1.00 50.31 O +ATOM 9637 CB LYS B 457 -70.990 18.323-129.203 1.00 66.05 C +ATOM 9638 CG LYS B 457 -71.738 18.025-130.499 1.00 68.68 C +ATOM 9639 CD LYS B 457 -73.242 18.045-130.305 1.00 62.63 C +ATOM 9640 CE LYS B 457 -73.956 18.410-131.597 1.00 62.05 C +ATOM 9641 NZ LYS B 457 -75.424 18.535-131.387 1.00 66.12 N +ATOM 9642 N LYS B 458 -68.784 16.182-129.163 1.00 46.90 N +ATOM 9643 CA LYS B 458 -67.971 15.150-129.796 1.00 40.97 C +ATOM 9644 C LYS B 458 -68.024 13.846-129.011 1.00 43.34 C +ATOM 9645 O LYS B 458 -68.176 12.768-129.595 1.00 39.85 O +ATOM 9646 CB LYS B 458 -66.529 15.638-129.933 1.00 38.00 C +ATOM 9647 CG LYS B 458 -65.545 14.549-130.313 1.00 46.34 C +ATOM 9648 CD LYS B 458 -64.144 15.104-130.525 1.00 54.44 C +ATOM 9649 CE LYS B 458 -63.123 13.979-130.635 1.00 62.21 C +ATOM 9650 NZ LYS B 458 -62.592 13.809-132.015 1.00 71.13 N +ATOM 9651 N THR B 459 -67.916 13.928-127.683 1.00 50.86 N +ATOM 9652 CA THR B 459 -67.914 12.721-126.861 1.00 49.76 C +ATOM 9653 C THR B 459 -69.226 11.960-127.001 1.00 48.91 C +ATOM 9654 O THR B 459 -69.234 10.726-127.074 1.00 44.78 O +ATOM 9655 CB THR B 459 -67.676 13.084-125.393 1.00 46.56 C +ATOM 9656 OG1 THR B 459 -66.495 13.884-125.271 1.00 44.88 O +ATOM 9657 CG2 THR B 459 -67.504 11.823-124.562 1.00 38.00 C +ATOM 9658 N LEU B 460 -70.346 12.685-127.057 1.00 54.42 N +ATOM 9659 CA LEU B 460 -71.649 12.033-127.128 1.00 52.35 C +ATOM 9660 C LEU B 460 -71.847 11.327-128.461 1.00 48.13 C +ATOM 9661 O LEU B 460 -72.437 10.242-128.513 1.00 46.17 O +ATOM 9662 CB LEU B 460 -72.757 13.061-126.898 1.00 54.51 C +ATOM 9663 CG LEU B 460 -74.195 12.540-126.942 1.00 54.16 C +ATOM 9664 CD1 LEU B 460 -74.372 11.331-126.033 1.00 49.45 C +ATOM 9665 CD2 LEU B 460 -75.172 13.649-126.573 1.00 54.62 C +ATOM 9666 N LEU B 461 -71.358 11.924-129.546 1.00 47.59 N +ATOM 9667 CA LEU B 461 -71.515 11.313-130.860 1.00 48.44 C +ATOM 9668 C LEU B 461 -70.729 10.010-130.954 1.00 48.86 C +ATOM 9669 O LEU B 461 -71.210 9.029-131.537 1.00 41.45 O +ATOM 9670 CB LEU B 461 -71.076 12.301-131.940 1.00 43.57 C +ATOM 9671 CG LEU B 461 -71.829 13.632-131.943 1.00 38.00 C +ATOM 9672 CD1 LEU B 461 -71.307 14.533-133.035 1.00 38.00 C +ATOM 9673 CD2 LEU B 461 -73.312 13.402-132.109 1.00 38.00 C +ATOM 9674 N HIS B 462 -69.512 9.985-130.395 1.00 48.92 N +ATOM 9675 CA HIS B 462 -68.720 8.757-130.394 1.00 46.93 C +ATOM 9676 C HIS B 462 -69.366 7.679-129.529 1.00 48.21 C +ATOM 9677 O HIS B 462 -69.330 6.493-129.879 1.00 43.81 O +ATOM 9678 CB HIS B 462 -67.296 9.040-129.910 1.00 41.07 C +ATOM 9679 CG HIS B 462 -66.456 9.807-130.884 1.00 41.15 C +ATOM 9680 ND1 HIS B 462 -65.587 9.194-131.759 1.00 41.92 N +ATOM 9681 CD2 HIS B 462 -66.330 11.138-131.102 1.00 47.10 C +ATOM 9682 CE1 HIS B 462 -64.975 10.111-132.488 1.00 47.16 C +ATOM 9683 NE2 HIS B 462 -65.408 11.299-132.108 1.00 49.19 N +ATOM 9684 N LEU B 463 -69.978 8.070-128.408 1.00 52.21 N +ATOM 9685 CA LEU B 463 -70.642 7.091-127.550 1.00 51.30 C +ATOM 9686 C LEU B 463 -71.889 6.541-128.222 1.00 51.85 C +ATOM 9687 O LEU B 463 -72.118 5.325-128.231 1.00 46.72 O +ATOM 9688 CB LEU B 463 -71.003 7.725-126.206 1.00 45.30 C +ATOM 9689 CG LEU B 463 -69.848 8.110-125.288 1.00 46.72 C +ATOM 9690 CD1 LEU B 463 -70.367 8.662-123.977 1.00 46.88 C +ATOM 9691 CD2 LEU B 463 -68.967 6.906-125.050 1.00 47.21 C +ATOM 9692 N GLN B 464 -72.705 7.429-128.800 1.00 50.67 N +ATOM 9693 CA GLN B 464 -73.903 6.986-129.499 1.00 48.79 C +ATOM 9694 C GLN B 464 -73.540 6.055-130.643 1.00 51.55 C +ATOM 9695 O GLN B 464 -74.189 5.021-130.846 1.00 49.60 O +ATOM 9696 CB GLN B 464 -74.693 8.194-130.016 1.00 51.27 C +ATOM 9697 CG GLN B 464 -75.450 8.974-128.946 1.00 51.52 C +ATOM 9698 CD GLN B 464 -76.133 10.220-129.492 1.00 54.84 C +ATOM 9699 OE1 GLN B 464 -75.935 10.599-130.646 1.00 54.01 O +ATOM 9700 NE2 GLN B 464 -76.945 10.859-128.660 1.00 60.17 N +ATOM 9701 N LEU B 465 -72.484 6.396-131.385 1.00 50.74 N +ATOM 9702 CA LEU B 465 -72.064 5.562-132.502 1.00 51.66 C +ATOM 9703 C LEU B 465 -71.654 4.179-132.022 1.00 50.53 C +ATOM 9704 O LEU B 465 -71.992 3.169-132.650 1.00 50.68 O +ATOM 9705 CB LEU B 465 -70.920 6.244-133.250 1.00 44.60 C +ATOM 9706 CG LEU B 465 -70.558 5.754-134.653 1.00 43.68 C +ATOM 9707 CD1 LEU B 465 -69.784 6.837-135.364 1.00 45.53 C +ATOM 9708 CD2 LEU B 465 -69.744 4.491-134.625 1.00 38.00 C +ATOM 9709 N LEU B 466 -70.920 4.116-130.912 1.00 50.33 N +ATOM 9710 CA LEU B 466 -70.433 2.853-130.367 1.00 53.87 C +ATOM 9711 C LEU B 466 -71.532 1.991-129.756 1.00 56.41 C +ATOM 9712 O LEU B 466 -71.234 0.888-129.281 1.00 53.39 O +ATOM 9713 CB LEU B 466 -69.338 3.131-129.337 1.00 51.55 C +ATOM 9714 CG LEU B 466 -68.001 3.557-129.946 1.00 44.84 C +ATOM 9715 CD1 LEU B 466 -67.125 4.223-128.915 1.00 44.49 C +ATOM 9716 CD2 LEU B 466 -67.299 2.339-130.527 1.00 46.13 C +ATOM 9717 N ALA B 467 -72.784 2.446-129.760 1.00 57.42 N +ATOM 9718 CA ALA B 467 -73.889 1.628-129.281 1.00 59.07 C +ATOM 9719 C ALA B 467 -74.584 0.853-130.394 1.00 56.26 C +ATOM 9720 O ALA B 467 -75.322 -0.093-130.098 1.00 51.27 O +ATOM 9721 CB ALA B 467 -74.915 2.503-128.552 1.00 60.19 C +ATOM 9722 N GLN B 468 -74.334 1.198-131.655 1.00 54.34 N +ATOM 9723 CA GLN B 468 -74.973 0.541-132.789 1.00 56.36 C +ATOM 9724 C GLN B 468 -74.204 -0.713-133.179 1.00 56.49 C +ATOM 9725 O GLN B 468 -72.975 -0.760-133.076 1.00 57.38 O +ATOM 9726 CB GLN B 468 -75.074 1.496-133.980 1.00 52.13 C +ATOM 9727 CG GLN B 468 -75.985 2.677-133.710 1.00 61.34 C +ATOM 9728 CD GLN B 468 -75.659 3.887-134.554 1.00 69.16 C +ATOM 9729 OE1 GLN B 468 -74.907 3.801-135.527 1.00 64.79 O +ATOM 9730 NE2 GLN B 468 -76.214 5.035-134.175 1.00 69.52 N +ATOM 9731 N ALA B 469 -74.944 -1.743-133.598 1.00 59.04 N +ATOM 9732 CA ALA B 469 -74.343 -3.053-133.837 1.00 57.72 C +ATOM 9733 C ALA B 469 -73.262 -3.009-134.912 1.00 57.13 C +ATOM 9734 O ALA B 469 -72.350 -3.845-134.904 1.00 55.03 O +ATOM 9735 CB ALA B 469 -75.423 -4.063-134.217 1.00 68.98 C +ATOM 9736 N ASP B 470 -73.354 -2.065-135.856 1.00 61.05 N +ATOM 9737 CA ASP B 470 -72.337 -1.957-136.901 1.00 58.00 C +ATOM 9738 C ASP B 470 -70.986 -1.513-136.343 1.00 49.93 C +ATOM 9739 O ASP B 470 -69.945 -1.806-136.943 1.00 46.86 O +ATOM 9740 CB ASP B 470 -72.804 -1.006-138.005 1.00 55.81 C +ATOM 9741 CG ASP B 470 -74.024 -1.527-138.752 1.00 50.88 C +ATOM 9742 OD1 ASP B 470 -73.924 -2.589-139.402 1.00 41.22 O +ATOM 9743 OD2 ASP B 470 -75.084 -0.871-138.694 1.00 60.91 O +ATOM 9744 N TYR B 471 -70.976 -0.796-135.222 1.00 52.74 N +ATOM 9745 CA TYR B 471 -69.728 -0.382-134.584 1.00 51.91 C +ATOM 9746 C TYR B 471 -69.839 -0.489-133.068 1.00 51.23 C +ATOM 9747 O TYR B 471 -69.522 0.448-132.335 1.00 47.70 O +ATOM 9748 CB TYR B 471 -69.345 1.046-134.964 1.00 52.77 C +ATOM 9749 CG TYR B 471 -69.793 1.501-136.332 1.00 51.67 C +ATOM 9750 CD1 TYR B 471 -71.054 2.044-136.525 1.00 56.17 C +ATOM 9751 CD2 TYR B 471 -68.943 1.419-137.423 1.00 56.96 C +ATOM 9752 CE1 TYR B 471 -71.461 2.476-137.766 1.00 63.19 C +ATOM 9753 CE2 TYR B 471 -69.342 1.848-138.668 1.00 58.21 C +ATOM 9754 CZ TYR B 471 -70.602 2.375-138.834 1.00 64.71 C +ATOM 9755 OH TYR B 471 -71.010 2.803-140.075 1.00 83.79 O +ATOM 9756 N ARG B 472 -70.280 -1.641-132.570 1.00 47.95 N +ATOM 9757 CA ARG B 472 -70.482 -1.769-131.133 1.00 55.25 C +ATOM 9758 C ARG B 472 -69.153 -1.852-130.393 1.00 54.66 C +ATOM 9759 O ARG B 472 -68.162 -2.383-130.900 1.00 51.02 O +ATOM 9760 CB ARG B 472 -71.337 -2.989-130.798 1.00 60.85 C +ATOM 9761 CG ARG B 472 -70.720 -4.328-131.121 1.00 55.81 C +ATOM 9762 CD ARG B 472 -71.477 -5.422-130.383 1.00 58.04 C +ATOM 9763 NE ARG B 472 -72.887 -5.074-130.200 1.00 62.37 N +ATOM 9764 CZ ARG B 472 -73.874 -5.444-131.013 1.00 70.53 C +ATOM 9765 NH1 ARG B 472 -73.626 -6.191-132.086 1.00 70.25 N +ATOM 9766 NH2 ARG B 472 -75.120 -5.066-130.749 1.00 73.31 N +ATOM 9767 N LEU B 473 -69.162 -1.337-129.159 1.00 53.90 N +ATOM 9768 CA LEU B 473 -67.930 -1.128-128.402 1.00 51.16 C +ATOM 9769 C LEU B 473 -67.226 -2.437-128.066 1.00 45.49 C +ATOM 9770 O LEU B 473 -65.993 -2.474-127.993 1.00 45.27 O +ATOM 9771 CB LEU B 473 -68.234 -0.359-127.118 1.00 47.28 C +ATOM 9772 CG LEU B 473 -67.028 0.008-126.256 1.00 38.27 C +ATOM 9773 CD1 LEU B 473 -66.056 0.817-127.078 1.00 38.00 C +ATOM 9774 CD2 LEU B 473 -67.455 0.774-125.022 1.00 43.08 C +ATOM 9775 N SER B 474 -67.976 -3.512-127.824 1.00 45.85 N +ATOM 9776 CA SER B 474 -67.313 -4.758-127.463 1.00 44.23 C +ATOM 9777 C SER B 474 -66.576 -5.345-128.652 1.00 46.59 C +ATOM 9778 O SER B 474 -65.452 -5.835-128.510 1.00 54.04 O +ATOM 9779 CB SER B 474 -68.316 -5.776-126.925 1.00 52.28 C +ATOM 9780 OG SER B 474 -69.323 -6.049-127.878 1.00 58.49 O +ATOM 9781 N ASP B 475 -67.182 -5.289-129.838 1.00 49.19 N +ATOM 9782 CA ASP B 475 -66.566 -5.939-130.987 1.00 49.88 C +ATOM 9783 C ASP B 475 -65.336 -5.179-131.462 1.00 43.82 C +ATOM 9784 O ASP B 475 -64.306 -5.792-131.764 1.00 47.84 O +ATOM 9785 CB ASP B 475 -67.586 -6.096-132.114 1.00 50.85 C +ATOM 9786 CG ASP B 475 -68.585 -7.205-131.839 1.00 51.13 C +ATOM 9787 OD1 ASP B 475 -68.267 -8.101-131.024 1.00 48.41 O +ATOM 9788 OD2 ASP B 475 -69.678 -7.192-132.445 1.00 54.51 O +ATOM 9789 N VAL B 476 -65.404 -3.847-131.497 1.00 40.27 N +ATOM 9790 CA VAL B 476 -64.248 -3.084-131.953 1.00 40.60 C +ATOM 9791 C VAL B 476 -63.112 -3.167-130.941 1.00 42.27 C +ATOM 9792 O VAL B 476 -61.935 -3.089-131.314 1.00 48.61 O +ATOM 9793 CB VAL B 476 -64.647 -1.628-132.250 1.00 39.59 C +ATOM 9794 CG1 VAL B 476 -65.637 -1.583-133.392 1.00 38.72 C +ATOM 9795 CG2 VAL B 476 -65.227 -0.969-131.015 1.00 51.14 C +ATOM 9796 N MET B 477 -63.427 -3.338-129.656 1.00 39.61 N +ATOM 9797 CA MET B 477 -62.370 -3.582-128.682 1.00 38.00 C +ATOM 9798 C MET B 477 -61.786 -4.975-128.861 1.00 38.32 C +ATOM 9799 O MET B 477 -60.567 -5.136-128.957 1.00 44.68 O +ATOM 9800 CB MET B 477 -62.898 -3.401-127.258 1.00 41.46 C +ATOM 9801 CG MET B 477 -62.962 -1.958-126.784 1.00 45.54 C +ATOM 9802 SD MET B 477 -61.373 -1.239-126.331 1.00 38.00 S +ATOM 9803 CE MET B 477 -60.942 -2.223-124.902 1.00 38.00 C +ATOM 9804 N ARG B 478 -62.646 -5.993-128.936 1.00 40.24 N +ATOM 9805 CA ARG B 478 -62.173 -7.368-129.076 1.00 38.00 C +ATOM 9806 C ARG B 478 -61.199 -7.508-130.235 1.00 42.08 C +ATOM 9807 O ARG B 478 -60.169 -8.182-130.111 1.00 42.56 O +ATOM 9808 CB ARG B 478 -63.362 -8.301-129.271 1.00 42.49 C +ATOM 9809 CG ARG B 478 -63.020 -9.761-129.436 1.00 38.00 C +ATOM 9810 CD ARG B 478 -64.150 -10.449-130.168 1.00 51.49 C +ATOM 9811 NE ARG B 478 -65.434 -9.803-129.901 1.00 54.71 N +ATOM 9812 CZ ARG B 478 -66.186 -10.038-128.830 1.00 64.80 C +ATOM 9813 NH1 ARG B 478 -65.774 -10.912-127.919 1.00 68.84 N +ATOM 9814 NH2 ARG B 478 -67.342 -9.397-128.669 1.00 53.25 N +ATOM 9815 N GLU B 479 -61.498 -6.857-131.365 1.00 45.27 N +ATOM 9816 CA GLU B 479 -60.637 -6.954-132.542 1.00 40.88 C +ATOM 9817 C GLU B 479 -59.357 -6.143-132.359 1.00 38.00 C +ATOM 9818 O GLU B 479 -58.260 -6.632-132.656 1.00 38.00 O +ATOM 9819 CB GLU B 479 -61.411 -6.497-133.783 1.00 38.00 C +ATOM 9820 CG GLU B 479 -60.744 -6.815-135.112 1.00 38.00 C +ATOM 9821 CD GLU B 479 -61.560 -6.353-136.317 1.00 48.08 C +ATOM 9822 OE1 GLU B 479 -62.753 -6.014-136.148 1.00 48.88 O +ATOM 9823 OE2 GLU B 479 -61.007 -6.336-137.439 1.00 48.75 O +ATOM 9824 N SER B 480 -59.473 -4.913-131.847 1.00 38.00 N +ATOM 9825 CA SER B 480 -58.289 -4.093-131.615 1.00 38.00 C +ATOM 9826 C SER B 480 -57.341 -4.746-130.619 1.00 38.00 C +ATOM 9827 O SER B 480 -56.120 -4.619-130.748 1.00 41.67 O +ATOM 9828 CB SER B 480 -58.701 -2.705-131.122 1.00 38.00 C +ATOM 9829 OG SER B 480 -57.580 -1.941-130.707 1.00 38.00 O +ATOM 9830 N LEU B 481 -57.875 -5.461-129.633 1.00 41.57 N +ATOM 9831 CA LEU B 481 -57.016 -6.125-128.666 1.00 39.87 C +ATOM 9832 C LEU B 481 -56.395 -7.395-129.217 1.00 38.03 C +ATOM 9833 O LEU B 481 -55.535 -7.981-128.554 1.00 43.45 O +ATOM 9834 CB LEU B 481 -57.789 -6.453-127.393 1.00 46.14 C +ATOM 9835 CG LEU B 481 -58.388 -5.243-126.676 1.00 47.20 C +ATOM 9836 CD1 LEU B 481 -59.382 -5.692-125.608 1.00 46.51 C +ATOM 9837 CD2 LEU B 481 -57.310 -4.341-126.097 1.00 38.98 C +ATOM 9838 N LEU B 482 -56.818 -7.848-130.395 1.00 38.00 N +ATOM 9839 CA LEU B 482 -56.192 -9.025-130.970 1.00 38.00 C +ATOM 9840 C LEU B 482 -54.796 -8.721-131.483 1.00 40.13 C +ATOM 9841 O LEU B 482 -53.976 -9.639-131.588 1.00 41.31 O +ATOM 9842 CB LEU B 482 -57.053 -9.587-132.096 1.00 38.00 C +ATOM 9843 CG LEU B 482 -58.226 -10.463-131.665 1.00 38.00 C +ATOM 9844 CD1 LEU B 482 -59.038 -10.880-132.869 1.00 38.00 C +ATOM 9845 CD2 LEU B 482 -57.701 -11.682-130.935 1.00 42.92 C +ATOM 9846 N GLU B 483 -54.492 -7.450-131.759 1.00 38.00 N +ATOM 9847 CA GLU B 483 -53.179 -7.074-132.270 1.00 39.67 C +ATOM 9848 C GLU B 483 -52.097 -7.126-131.204 1.00 45.06 C +ATOM 9849 O GLU B 483 -50.956 -6.745-131.486 1.00 56.00 O +ATOM 9850 CB GLU B 483 -53.224 -5.665-132.866 1.00 38.00 C +ATOM 9851 CG GLU B 483 -54.564 -5.280-133.459 1.00 38.48 C +ATOM 9852 CD GLU B 483 -54.608 -3.814-133.883 1.00 44.79 C +ATOM 9853 OE1 GLU B 483 -54.156 -2.955-133.085 1.00 38.00 O +ATOM 9854 OE2 GLU B 483 -55.127 -3.516-134.988 1.00 39.37 O +ATOM 9855 N ASP B 484 -52.414 -7.576-129.998 1.00 44.44 N +ATOM 9856 CA ASP B 484 -51.448 -7.617-128.916 1.00 41.71 C +ATOM 9857 C ASP B 484 -50.964 -9.039-128.674 1.00 39.73 C +ATOM 9858 O ASP B 484 -51.729 -10.001-128.774 1.00 42.65 O +ATOM 9859 CB ASP B 484 -52.051 -7.059-127.632 1.00 41.82 C +ATOM 9860 CG ASP B 484 -51.003 -6.710-126.620 1.00 42.28 C +ATOM 9861 OD1 ASP B 484 -49.810 -6.786-126.966 1.00 41.85 O +ATOM 9862 OD2 ASP B 484 -51.365 -6.385-125.476 1.00 49.77 O +ATOM 9863 N GLN B 485 -49.685 -9.155-128.313 1.00 40.64 N +ATOM 9864 CA GLN B 485 -49.095 -10.461-128.064 1.00 38.00 C +ATOM 9865 C GLN B 485 -49.764 -11.169-126.902 1.00 38.00 C +ATOM 9866 O GLN B 485 -49.732 -12.402-126.832 1.00 38.00 O +ATOM 9867 CB GLN B 485 -47.599 -10.308-127.802 1.00 39.99 C +ATOM 9868 CG GLN B 485 -46.856 -11.611-127.694 1.00 45.71 C +ATOM 9869 CD GLN B 485 -45.376 -11.431-127.893 1.00 57.73 C +ATOM 9870 OE1 GLN B 485 -44.939 -10.854-128.896 1.00 60.57 O +ATOM 9871 NE2 GLN B 485 -44.589 -11.912-126.937 1.00 50.20 N +ATOM 9872 N LEU B 486 -50.402 -10.418-126.010 1.00 39.33 N +ATOM 9873 CA LEU B 486 -51.038 -10.977-124.831 1.00 43.56 C +ATOM 9874 C LEU B 486 -52.498 -11.348-125.066 1.00 48.12 C +ATOM 9875 O LEU B 486 -53.249 -11.500-124.096 1.00 54.37 O +ATOM 9876 CB LEU B 486 -50.936 -9.987-123.672 1.00 38.00 C +ATOM 9877 CG LEU B 486 -49.521 -9.625-123.248 1.00 38.00 C +ATOM 9878 CD1 LEU B 486 -49.591 -8.882-121.943 1.00 41.82 C +ATOM 9879 CD2 LEU B 486 -48.675 -10.873-123.110 1.00 39.44 C +ATOM 9880 N SER B 487 -52.910 -11.514-126.316 1.00 40.35 N +ATOM 9881 CA SER B 487 -54.298 -11.839-126.597 1.00 38.00 C +ATOM 9882 C SER B 487 -54.637 -13.233-126.074 1.00 42.55 C +ATOM 9883 O SER B 487 -53.843 -14.165-126.235 1.00 41.51 O +ATOM 9884 CB SER B 487 -54.563 -11.760-128.095 1.00 42.83 C +ATOM 9885 OG SER B 487 -54.419 -10.424-128.539 1.00 52.57 O +ATOM 9886 N PRO B 488 -55.816 -13.412-125.445 1.00 46.17 N +ATOM 9887 CA PRO B 488 -56.828 -12.367-125.234 1.00 48.79 C +ATOM 9888 C PRO B 488 -56.560 -11.512-123.991 1.00 44.02 C +ATOM 9889 O PRO B 488 -56.457 -12.050-122.891 1.00 41.14 O +ATOM 9890 CB PRO B 488 -58.118 -13.172-125.076 1.00 40.64 C +ATOM 9891 CG PRO B 488 -57.668 -14.449-124.444 1.00 38.00 C +ATOM 9892 CD PRO B 488 -56.275 -14.726-124.955 1.00 38.00 C +ATOM 9893 N VAL B 489 -56.469 -10.191-124.159 1.00 42.21 N +ATOM 9894 CA VAL B 489 -56.148 -9.341-123.017 1.00 41.48 C +ATOM 9895 C VAL B 489 -57.360 -9.092-122.130 1.00 42.62 C +ATOM 9896 O VAL B 489 -57.194 -8.782-120.943 1.00 43.20 O +ATOM 9897 CB VAL B 489 -55.541 -8.004-123.479 1.00 39.68 C +ATOM 9898 CG1 VAL B 489 -54.364 -8.247-124.406 1.00 42.54 C +ATOM 9899 CG2 VAL B 489 -56.570 -7.178-124.163 1.00 40.78 C +ATOM 9900 N LEU B 490 -58.572 -9.220-122.669 1.00 47.95 N +ATOM 9901 CA LEU B 490 -59.808 -9.084-121.907 1.00 47.58 C +ATOM 9902 C LEU B 490 -60.648 -10.334-122.096 1.00 44.79 C +ATOM 9903 O LEU B 490 -60.842 -10.791-123.227 1.00 45.03 O +ATOM 9904 CB LEU B 490 -60.617 -7.858-122.341 1.00 39.10 C +ATOM 9905 CG LEU B 490 -60.112 -6.505-121.858 1.00 38.00 C +ATOM 9906 CD1 LEU B 490 -61.041 -5.405-122.313 1.00 38.00 C +ATOM 9907 CD2 LEU B 490 -59.993 -6.513-120.350 1.00 38.00 C +ATOM 9908 N THR B 491 -61.160 -10.875-120.997 1.00 39.76 N +ATOM 9909 CA THR B 491 -62.049 -12.015-121.103 1.00 46.31 C +ATOM 9910 C THR B 491 -63.388 -11.574-121.700 1.00 54.60 C +ATOM 9911 O THR B 491 -63.650 -10.384-121.897 1.00 56.58 O +ATOM 9912 CB THR B 491 -62.227 -12.672-119.734 1.00 47.58 C +ATOM 9913 OG1 THR B 491 -63.059 -11.851-118.907 1.00 57.89 O +ATOM 9914 CG2 THR B 491 -60.880 -12.837-119.056 1.00 39.87 C +ATOM 9915 N GLU B 492 -64.230 -12.556-122.023 1.00 58.10 N +ATOM 9916 CA GLU B 492 -65.515 -12.241-122.644 1.00 52.38 C +ATOM 9917 C GLU B 492 -66.447 -11.449-121.734 1.00 45.91 C +ATOM 9918 O GLU B 492 -67.061 -10.485-122.224 1.00 39.98 O +ATOM 9919 CB GLU B 492 -66.192 -13.530-123.131 1.00 49.42 C +ATOM 9920 CG GLU B 492 -65.662 -14.038-124.460 1.00 61.22 C +ATOM 9921 CD GLU B 492 -65.762 -12.996-125.558 1.00 61.57 C +ATOM 9922 OE1 GLU B 492 -66.839 -12.383-125.691 1.00 55.63 O +ATOM 9923 OE2 GLU B 492 -64.769 -12.800-126.297 1.00 59.83 O +ATOM 9924 N PRO B 493 -66.609 -11.779-120.445 1.00 47.01 N +ATOM 9925 CA PRO B 493 -67.465 -10.942-119.590 1.00 47.25 C +ATOM 9926 C PRO B 493 -67.040 -9.484-119.519 1.00 45.91 C +ATOM 9927 O PRO B 493 -67.908 -8.605-119.433 1.00 46.75 O +ATOM 9928 CB PRO B 493 -67.351 -11.623-118.219 1.00 45.53 C +ATOM 9929 CG PRO B 493 -67.062 -13.029-118.527 1.00 43.95 C +ATOM 9930 CD PRO B 493 -66.180 -13.001-119.734 1.00 47.97 C +ATOM 9931 N HIS B 494 -65.738 -9.192-119.556 1.00 43.74 N +ATOM 9932 CA HIS B 494 -65.308 -7.799-119.497 1.00 46.76 C +ATOM 9933 C HIS B 494 -65.717 -7.040-120.753 1.00 48.49 C +ATOM 9934 O HIS B 494 -66.188 -5.899-120.668 1.00 45.04 O +ATOM 9935 CB HIS B 494 -63.797 -7.713-119.286 1.00 46.68 C +ATOM 9936 CG HIS B 494 -63.360 -8.051-117.895 1.00 48.83 C +ATOM 9937 ND1 HIS B 494 -62.754 -9.248-117.577 1.00 53.37 N +ATOM 9938 CD2 HIS B 494 -63.426 -7.346-116.741 1.00 43.26 C +ATOM 9939 CE1 HIS B 494 -62.472 -9.268-116.287 1.00 46.68 C +ATOM 9940 NE2 HIS B 494 -62.871 -8.126-115.757 1.00 46.00 N +ATOM 9941 N LEU B 495 -65.540 -7.651-121.926 1.00 48.80 N +ATOM 9942 CA LEU B 495 -65.872 -6.964-123.169 1.00 44.78 C +ATOM 9943 C LEU B 495 -67.359 -6.646-123.235 1.00 48.28 C +ATOM 9944 O LEU B 495 -67.748 -5.504-123.507 1.00 49.75 O +ATOM 9945 CB LEU B 495 -65.442 -7.809-124.367 1.00 45.53 C +ATOM 9946 CG LEU B 495 -63.936 -7.974-124.562 1.00 44.27 C +ATOM 9947 CD1 LEU B 495 -63.652 -9.068-125.568 1.00 45.58 C +ATOM 9948 CD2 LEU B 495 -63.329 -6.658-125.019 1.00 38.00 C +ATOM 9949 N LEU B 496 -68.209 -7.632-122.932 1.00 48.16 N +ATOM 9950 CA LEU B 496 -69.648 -7.390-122.960 1.00 46.78 C +ATOM 9951 C LEU B 496 -70.054 -6.345-121.938 1.00 50.03 C +ATOM 9952 O LEU B 496 -71.056 -5.647-122.129 1.00 53.53 O +ATOM 9953 CB LEU B 496 -70.408 -8.688-122.704 1.00 43.24 C +ATOM 9954 CG LEU B 496 -70.348 -9.728-123.816 1.00 47.04 C +ATOM 9955 CD1 LEU B 496 -71.439 -10.761-123.619 1.00 49.24 C +ATOM 9956 CD2 LEU B 496 -70.482 -9.052-125.171 1.00 56.75 C +ATOM 9957 N ALA B 497 -69.287 -6.213-120.855 1.00 46.20 N +ATOM 9958 CA ALA B 497 -69.602 -5.202-119.858 1.00 46.97 C +ATOM 9959 C ALA B 497 -69.480 -3.798-120.430 1.00 47.25 C +ATOM 9960 O ALA B 497 -70.236 -2.903-120.036 1.00 50.40 O +ATOM 9961 CB ALA B 497 -68.695 -5.364-118.641 1.00 50.11 C +ATOM 9962 N LEU B 498 -68.555 -3.587-121.368 1.00 43.89 N +ATOM 9963 CA LEU B 498 -68.407 -2.264-121.965 1.00 46.09 C +ATOM 9964 C LEU B 498 -69.692 -1.808-122.647 1.00 48.49 C +ATOM 9965 O LEU B 498 -70.074 -0.637-122.541 1.00 49.62 O +ATOM 9966 CB LEU B 498 -67.237 -2.257-122.945 1.00 41.29 C +ATOM 9967 CG LEU B 498 -65.891 -2.581-122.307 1.00 38.00 C +ATOM 9968 CD1 LEU B 498 -64.828 -2.700-123.361 1.00 38.16 C +ATOM 9969 CD2 LEU B 498 -65.536 -1.498-121.334 1.00 38.00 C +ATOM 9970 N ASP B 499 -70.379 -2.717-123.344 1.00 48.16 N +ATOM 9971 CA ASP B 499 -71.642 -2.353-123.982 1.00 59.92 C +ATOM 9972 C ASP B 499 -72.678 -1.932-122.948 1.00 55.98 C +ATOM 9973 O ASP B 499 -73.319 -0.882-123.082 1.00 53.76 O +ATOM 9974 CB ASP B 499 -72.175 -3.520-124.814 1.00 67.95 C +ATOM 9975 CG ASP B 499 -71.384 -3.744-126.081 1.00 59.19 C +ATOM 9976 OD1 ASP B 499 -70.778 -2.775-126.588 1.00 59.81 O +ATOM 9977 OD2 ASP B 499 -71.383 -4.890-126.575 1.00 59.67 O +ATOM 9978 N ARG B 500 -72.859 -2.753-121.912 1.00 54.09 N +ATOM 9979 CA ARG B 500 -73.858 -2.470-120.888 1.00 53.48 C +ATOM 9980 C ARG B 500 -73.562 -1.162-120.166 1.00 47.86 C +ATOM 9981 O ARG B 500 -74.462 -0.336-119.967 1.00 45.15 O +ATOM 9982 CB ARG B 500 -73.912 -3.638-119.906 1.00 53.17 C +ATOM 9983 CG ARG B 500 -74.676 -3.378-118.628 1.00 55.08 C +ATOM 9984 CD ARG B 500 -74.455 -4.529-117.662 1.00 49.69 C +ATOM 9985 NE ARG B 500 -73.049 -4.918-117.594 1.00 42.65 N +ATOM 9986 CZ ARG B 500 -72.531 -5.683-116.639 1.00 48.90 C +ATOM 9987 NH1 ARG B 500 -73.304 -6.146-115.667 1.00 57.79 N +ATOM 9988 NH2 ARG B 500 -71.241 -5.983-116.650 1.00 49.34 N +ATOM 9989 N ARG B 501 -72.300 -0.945-119.785 1.00 46.22 N +ATOM 9990 CA ARG B 501 -71.934 0.304-119.128 1.00 48.42 C +ATOM 9991 C ARG B 501 -72.099 1.494-120.060 1.00 48.34 C +ATOM 9992 O ARG B 501 -72.353 2.611-119.596 1.00 45.09 O +ATOM 9993 CB ARG B 501 -70.495 0.236-118.615 1.00 45.61 C +ATOM 9994 CG ARG B 501 -70.237 -0.893-117.630 1.00 45.45 C +ATOM 9995 CD ARG B 501 -68.927 -0.700-116.885 1.00 44.07 C +ATOM 9996 NE ARG B 501 -68.584 -1.879-116.098 1.00 48.84 N +ATOM 9997 CZ ARG B 501 -67.570 -2.689-116.380 1.00 46.36 C +ATOM 9998 NH1 ARG B 501 -66.795 -2.433-117.423 1.00 42.74 N +ATOM 9999 NH2 ARG B 501 -67.329 -3.749-115.617 1.00 45.33 N +ATOM 10000 N LEU B 502 -71.977 1.274-121.372 1.00 52.90 N +ATOM 10001 CA LEU B 502 -72.202 2.358-122.322 1.00 55.85 C +ATOM 10002 C LEU B 502 -73.660 2.804-122.300 1.00 53.26 C +ATOM 10003 O LEU B 502 -73.947 4.008-122.317 1.00 46.95 O +ATOM 10004 CB LEU B 502 -71.776 1.918-123.728 1.00 53.46 C +ATOM 10005 CG LEU B 502 -71.965 2.874-124.913 1.00 54.87 C +ATOM 10006 CD1 LEU B 502 -71.052 4.085-124.824 1.00 44.55 C +ATOM 10007 CD2 LEU B 502 -71.737 2.137-126.220 1.00 51.49 C +ATOM 10008 N GLN B 503 -74.589 1.847-122.219 1.00 54.26 N +ATOM 10009 CA GLN B 503 -76.000 2.196-122.101 1.00 53.54 C +ATOM 10010 C GLN B 503 -76.247 3.043-120.866 1.00 52.66 C +ATOM 10011 O GLN B 503 -76.988 4.031-120.921 1.00 56.14 O +ATOM 10012 CB GLN B 503 -76.854 0.930-122.056 1.00 54.89 C +ATOM 10013 CG GLN B 503 -76.933 0.194-123.371 1.00 57.16 C +ATOM 10014 CD GLN B 503 -77.662 1.003-124.423 1.00 65.11 C +ATOM 10015 OE1 GLN B 503 -78.746 1.532-124.171 1.00 70.33 O +ATOM 10016 NE2 GLN B 503 -77.074 1.103-125.609 1.00 69.93 N +ATOM 10017 N THR B 504 -75.626 2.677-119.745 1.00 47.27 N +ATOM 10018 CA THR B 504 -75.803 3.440-118.517 1.00 46.27 C +ATOM 10019 C THR B 504 -75.331 4.880-118.689 1.00 48.24 C +ATOM 10020 O THR B 504 -75.931 5.810-118.137 1.00 44.83 O +ATOM 10021 CB THR B 504 -75.066 2.742-117.378 1.00 41.05 C +ATOM 10022 OG1 THR B 504 -75.575 1.409-117.247 1.00 38.00 O +ATOM 10023 CG2 THR B 504 -75.259 3.485-116.074 1.00 43.19 C +ATOM 10024 N ILE B 505 -74.269 5.090-119.466 1.00 48.76 N +ATOM 10025 CA ILE B 505 -73.821 6.452-119.736 1.00 50.34 C +ATOM 10026 C ILE B 505 -74.812 7.160-120.649 1.00 47.69 C +ATOM 10027 O ILE B 505 -75.239 8.287-120.375 1.00 46.29 O +ATOM 10028 CB ILE B 505 -72.403 6.442-120.332 1.00 50.07 C +ATOM 10029 CG1 ILE B 505 -71.459 5.677-119.417 1.00 48.61 C +ATOM 10030 CG2 ILE B 505 -71.874 7.855-120.490 1.00 46.01 C +ATOM 10031 CD1 ILE B 505 -70.127 5.408-120.034 1.00 51.72 C +ATOM 10032 N LEU B 506 -75.225 6.492-121.726 1.00 47.30 N +ATOM 10033 CA LEU B 506 -76.176 7.106-122.645 1.00 49.11 C +ATOM 10034 C LEU B 506 -77.516 7.344-121.969 1.00 51.25 C +ATOM 10035 O LEU B 506 -78.107 8.420-122.112 1.00 50.18 O +ATOM 10036 CB LEU B 506 -76.353 6.220-123.873 1.00 49.92 C +ATOM 10037 CG LEU B 506 -75.122 6.100-124.758 1.00 44.79 C +ATOM 10038 CD1 LEU B 506 -75.369 5.061-125.830 1.00 42.64 C +ATOM 10039 CD2 LEU B 506 -74.812 7.457-125.363 1.00 42.75 C +ATOM 10040 N ARG B 507 -77.995 6.361-121.206 1.00 56.27 N +ATOM 10041 CA ARG B 507 -79.240 6.538-120.470 1.00 57.43 C +ATOM 10042 C ARG B 507 -79.127 7.684-119.477 1.00 55.73 C +ATOM 10043 O ARG B 507 -80.112 8.388-119.229 1.00 59.82 O +ATOM 10044 CB ARG B 507 -79.616 5.235-119.763 1.00 56.67 C +ATOM 10045 CG ARG B 507 -80.879 5.291-118.918 1.00 59.98 C +ATOM 10046 CD ARG B 507 -81.345 3.886-118.532 1.00 61.95 C +ATOM 10047 NE ARG B 507 -80.268 3.066-117.980 1.00 55.21 N +ATOM 10048 CZ ARG B 507 -79.638 2.111-118.656 1.00 47.69 C +ATOM 10049 NH1 ARG B 507 -79.976 1.865-119.914 1.00 46.11 N +ATOM 10050 NH2 ARG B 507 -78.668 1.414-118.079 1.00 43.54 N +ATOM 10051 N THR B 508 -77.930 7.899-118.920 1.00 50.78 N +ATOM 10052 CA THR B 508 -77.718 9.011-117.998 1.00 52.02 C +ATOM 10053 C THR B 508 -77.793 10.348-118.725 1.00 55.83 C +ATOM 10054 O THR B 508 -78.326 11.327-118.189 1.00 54.70 O +ATOM 10055 CB THR B 508 -76.365 8.866-117.301 1.00 46.35 C +ATOM 10056 OG1 THR B 508 -76.309 7.609-116.617 1.00 40.11 O +ATOM 10057 CG2 THR B 508 -76.162 9.992-116.294 1.00 49.62 C +ATOM 10058 N VAL B 509 -77.250 10.414-119.941 1.00 53.63 N +ATOM 10059 CA VAL B 509 -77.315 11.652-120.710 1.00 53.78 C +ATOM 10060 C VAL B 509 -78.765 11.991-121.023 1.00 60.47 C +ATOM 10061 O VAL B 509 -79.277 13.044-120.625 1.00 64.90 O +ATOM 10062 CB VAL B 509 -76.471 11.535-121.990 1.00 47.20 C +ATOM 10063 CG1 VAL B 509 -76.626 12.781-122.847 1.00 46.35 C +ATOM 10064 CG2 VAL B 509 -75.009 11.315-121.634 1.00 45.71 C +ATOM 10065 N GLU B 510 -79.467 11.065-121.680 1.00 62.47 N +ATOM 10066 CA GLU B 510 -80.869 11.294-122.010 1.00 74.04 C +ATOM 10067 C GLU B 510 -81.732 11.374-120.758 1.00 70.99 C +ATOM 10068 O GLU B 510 -82.766 12.053-120.763 1.00 74.29 O +ATOM 10069 CB GLU B 510 -81.372 10.191-122.946 1.00 81.34 C +ATOM 10070 CG GLU B 510 -81.787 8.891-122.248 1.00 79.37 C +ATOM 10071 CD GLU B 510 -82.295 7.839-123.221 1.00 84.61 C +ATOM 10072 OE1 GLU B 510 -82.824 8.220-124.287 1.00 97.49 O +ATOM 10073 OE2 GLU B 510 -82.165 6.631-122.922 1.00 84.94 O +ATOM 10074 N GLY B 511 -81.309 10.724-119.673 1.00 65.75 N +ATOM 10075 CA GLY B 511 -82.100 10.753-118.455 1.00 69.61 C +ATOM 10076 C GLY B 511 -82.142 12.135-117.836 1.00 66.46 C +ATOM 10077 O GLY B 511 -83.212 12.642-117.492 1.00 67.60 O +ATOM 10078 N CYS B 512 -80.981 12.762-117.685 1.00 65.79 N +ATOM 10079 CA CYS B 512 -80.929 14.103-117.128 1.00 75.15 C +ATOM 10080 C CYS B 512 -81.103 15.182-118.193 1.00 70.56 C +ATOM 10081 O CYS B 512 -81.127 16.370-117.855 1.00 72.11 O +ATOM 10082 CB CYS B 512 -79.626 14.292-116.328 1.00 78.36 C +ATOM 10083 SG CYS B 512 -78.128 14.697-117.249 1.00 68.07 S +ATOM 10084 N ILE B 513 -81.283 14.795-119.458 1.00 65.17 N +ATOM 10085 CA ILE B 513 -81.685 15.759-120.478 1.00 69.72 C +ATOM 10086 C ILE B 513 -83.107 16.248-120.222 1.00 73.61 C +ATOM 10087 O ILE B 513 -83.413 17.430-120.416 1.00 69.74 O +ATOM 10088 CB ILE B 513 -81.533 15.141-121.881 1.00 69.66 C +ATOM 10089 CG1 ILE B 513 -80.272 15.672-122.563 1.00 71.45 C +ATOM 10090 CG2 ILE B 513 -82.754 15.413-122.745 1.00 69.49 C +ATOM 10091 CD1 ILE B 513 -80.076 15.155-123.971 1.00 66.32 C +ATOM 10092 N VAL B 514 -83.987 15.359-119.750 1.00 75.45 N +ATOM 10093 CA VAL B 514 -85.383 15.718-119.507 1.00 76.21 C +ATOM 10094 C VAL B 514 -85.523 16.775-118.421 1.00 77.96 C +ATOM 10095 O VAL B 514 -86.546 17.469-118.360 1.00 88.48 O +ATOM 10096 CB VAL B 514 -86.207 14.463-119.146 1.00 69.18 C +ATOM 10097 CG1 VAL B 514 -85.833 13.302-120.055 1.00 61.94 C +ATOM 10098 CG2 VAL B 514 -86.024 14.100-117.672 1.00 63.02 C +ATOM 10099 N ALA B 515 -84.520 16.919-117.557 1.00 73.38 N +ATOM 10100 CA ALA B 515 -84.572 17.893-116.481 1.00 71.53 C +ATOM 10101 C ALA B 515 -83.881 19.201-116.832 1.00 72.04 C +ATOM 10102 O ALA B 515 -84.117 20.207-116.155 1.00 77.83 O +ATOM 10103 CB ALA B 515 -83.939 17.307-115.213 1.00 67.32 C +ATOM 10104 N HIS B 516 -83.059 19.219-117.883 1.00 66.85 N +ATOM 10105 CA HIS B 516 -82.336 20.419-118.279 1.00 73.39 C +ATOM 10106 C HIS B 516 -82.408 20.712-119.772 1.00 72.35 C +ATOM 10107 O HIS B 516 -82.082 21.837-120.172 1.00 71.15 O +ATOM 10108 CB HIS B 516 -80.857 20.319-117.869 1.00 75.30 C +ATOM 10109 CG HIS B 516 -80.642 20.055-116.409 1.00 68.77 C +ATOM 10110 ND1 HIS B 516 -80.976 18.858-115.811 1.00 62.71 N +ATOM 10111 CD2 HIS B 516 -80.101 20.823-115.434 1.00 63.04 C +ATOM 10112 CE1 HIS B 516 -80.662 18.904-114.528 1.00 57.95 C +ATOM 10113 NE2 HIS B 516 -80.129 20.086-114.274 1.00 59.78 N +ATOM 10114 N GLY B 517 -82.824 19.755-120.602 1.00 68.67 N +ATOM 10115 CA GLY B 517 -82.887 19.960-122.034 1.00 72.61 C +ATOM 10116 C GLY B 517 -81.526 19.920-122.701 1.00 78.86 C +ATOM 10117 O GLY B 517 -80.475 19.991-122.067 1.00 81.37 O +ATOM 10118 N GLN B 518 -81.551 19.821-124.028 1.00 69.32 N +ATOM 10119 CA GLN B 518 -80.303 19.810-124.793 1.00 64.07 C +ATOM 10120 C GLN B 518 -79.530 21.122-124.689 1.00 67.36 C +ATOM 10121 O GLN B 518 -78.464 21.237-125.297 1.00 61.97 O +ATOM 10122 CB GLN B 518 -80.606 19.492-126.258 1.00 61.93 C +ATOM 10123 CG GLN B 518 -81.158 18.099-126.467 1.00 61.55 C +ATOM 10124 CD GLN B 518 -81.221 17.713-127.931 1.00 78.06 C +ATOM 10125 OE1 GLN B 518 -80.620 18.363-128.794 1.00 86.73 O +ATOM 10126 NE2 GLN B 518 -81.978 16.669-128.225 1.00 68.19 N +ATOM 10127 N GLN B 519 -80.052 22.109-123.960 1.00 77.20 N +ATOM 10128 CA GLN B 519 -79.351 23.374-123.762 1.00 77.67 C +ATOM 10129 C GLN B 519 -78.086 23.192-122.927 1.00 79.26 C +ATOM 10130 O GLN B 519 -76.979 23.537-123.362 1.00 79.45 O +ATOM 10131 CB GLN B 519 -80.293 24.391-123.099 1.00 91.23 C +ATOM 10132 CG GLN B 519 -79.623 25.500-122.255 1.00106.67 C +ATOM 10133 CD GLN B 519 -80.196 25.620-120.831 1.00 98.36 C +ATOM 10134 OE1 GLN B 519 -80.576 24.622-120.210 1.00 81.40 O +ATOM 10135 NE2 GLN B 519 -80.256 26.851-120.316 1.00 97.48 N +ATOM 10136 N SER B 520 -78.229 22.652-121.717 1.00 75.61 N +ATOM 10137 CA SER B 520 -77.126 22.588-120.770 1.00 77.82 C +ATOM 10138 C SER B 520 -76.554 21.185-120.628 1.00 71.72 C +ATOM 10139 O SER B 520 -75.675 20.971-119.789 1.00 69.41 O +ATOM 10140 CB SER B 520 -77.567 23.125-119.406 1.00 84.76 C +ATOM 10141 OG SER B 520 -76.506 23.065-118.466 1.00 83.75 O +ATOM 10142 N VAL B 521 -77.023 20.226-121.426 1.00 69.94 N +ATOM 10143 CA VAL B 521 -76.499 18.865-121.398 1.00 65.07 C +ATOM 10144 C VAL B 521 -75.693 18.526-122.644 1.00 61.55 C +ATOM 10145 O VAL B 521 -75.102 17.439-122.711 1.00 63.89 O +ATOM 10146 CB VAL B 521 -77.627 17.838-121.178 1.00 62.23 C +ATOM 10147 CG1 VAL B 521 -77.068 16.525-120.661 1.00 54.92 C +ATOM 10148 CG2 VAL B 521 -78.632 18.376-120.182 1.00 67.63 C +ATOM 10149 N ILE B 522 -75.621 19.428-123.621 1.00 65.24 N +ATOM 10150 CA ILE B 522 -74.779 19.261-124.801 1.00 58.34 C +ATOM 10151 C ILE B 522 -74.011 20.559-124.988 1.00 59.67 C +ATOM 10152 O ILE B 522 -74.618 21.630-125.106 1.00 68.56 O +ATOM 10153 CB ILE B 522 -75.589 18.924-126.067 1.00 49.33 C +ATOM 10154 CG1 ILE B 522 -75.797 17.415-126.211 1.00 38.00 C +ATOM 10155 CG2 ILE B 522 -74.904 19.463-127.306 1.00 53.77 C +ATOM 10156 CD1 ILE B 522 -76.944 16.873-125.414 1.00 38.00 C +ATOM 10157 N VAL B 523 -72.692 20.472-125.009 1.00 58.05 N +ATOM 10158 CA VAL B 523 -71.832 21.649-125.117 1.00 72.40 C +ATOM 10159 C VAL B 523 -71.053 21.508-126.420 1.00 77.14 C +ATOM 10160 O VAL B 523 -69.951 20.956-126.463 1.00 78.43 O +ATOM 10161 CB VAL B 523 -70.906 21.810-123.910 1.00 69.72 C +ATOM 10162 CG1 VAL B 523 -71.548 22.720-122.874 1.00 65.41 C +ATOM 10163 CG2 VAL B 523 -70.619 20.461-123.303 1.00 63.11 C +ATOM 10164 N ASP B 524 -71.639 22.013-127.503 1.00 81.35 N +ATOM 10165 CA ASP B 524 -71.059 21.892-128.835 1.00 82.36 C +ATOM 10166 C ASP B 524 -69.998 22.952-129.107 1.00 92.40 C +ATOM 10167 O ASP B 524 -70.010 23.580-130.169 1.00104.80 O +ATOM 10168 CB ASP B 524 -72.172 21.954-129.884 1.00 84.69 C +ATOM 10169 CG ASP B 524 -73.085 23.151-129.691 1.00 93.85 C +ATOM 10170 OD1 ASP B 524 -73.252 23.592-128.533 1.00 91.25 O +ATOM 10171 OD2 ASP B 524 -73.650 23.638-130.694 1.00 95.23 O +ATOM 10172 N GLY B 525 -69.077 23.156-128.163 1.00 88.52 N +ATOM 10173 CA GLY B 525 -67.959 24.046-128.378 1.00 93.03 C +ATOM 10174 C GLY B 525 -67.093 23.568-129.529 1.00112.29 C +ATOM 10175 O GLY B 525 -67.099 22.386-129.890 1.00114.27 O +ATOM 10176 N PRO B 526 -66.322 24.485-130.138 1.00122.71 N +ATOM 10177 CA PRO B 526 -65.517 24.160-131.326 1.00119.46 C +ATOM 10178 C PRO B 526 -64.277 23.312-131.028 1.00107.50 C +ATOM 10179 O PRO B 526 -63.747 23.369-129.918 1.00110.55 O +ATOM 10180 CB PRO B 526 -65.110 25.539-131.856 1.00121.60 C +ATOM 10181 CG PRO B 526 -65.099 26.413-130.645 1.00121.97 C +ATOM 10182 CD PRO B 526 -66.189 25.899-129.742 1.00110.36 C +TER 10183 PRO B 526 +ATOM 10184 N SER D 134 -68.452 -48.343 -88.356 1.00 80.72 N +ATOM 10185 CA SER D 134 -68.005 -49.716 -88.534 1.00 74.62 C +ATOM 10186 C SER D 134 -66.487 -49.763 -88.680 1.00 75.95 C +ATOM 10187 O SER D 134 -65.814 -50.491 -87.950 1.00 69.67 O +ATOM 10188 CB SER D 134 -68.690 -50.354 -89.755 1.00 85.30 C +ATOM 10189 OG SER D 134 -68.248 -49.778 -90.977 1.00 85.81 O +ATOM 10190 N VAL D 135 -65.955 -48.967 -89.614 1.00 77.44 N +ATOM 10191 CA VAL D 135 -64.514 -48.965 -89.861 1.00 71.59 C +ATOM 10192 C VAL D 135 -63.772 -48.530 -88.609 1.00 73.45 C +ATOM 10193 O VAL D 135 -62.827 -49.189 -88.158 1.00 75.18 O +ATOM 10194 CB VAL D 135 -64.170 -48.057 -91.055 1.00 59.56 C +ATOM 10195 CG1 VAL D 135 -62.817 -48.436 -91.617 1.00 62.54 C +ATOM 10196 CG2 VAL D 135 -65.247 -48.136 -92.117 1.00 59.91 C +ATOM 10197 N LEU D 136 -64.190 -47.403 -88.034 1.00 75.09 N +ATOM 10198 CA LEU D 136 -63.598 -46.932 -86.789 1.00 81.48 C +ATOM 10199 C LEU D 136 -63.889 -47.898 -85.646 1.00 81.73 C +ATOM 10200 O LEU D 136 -63.025 -48.146 -84.795 1.00 71.94 O +ATOM 10201 CB LEU D 136 -64.119 -45.533 -86.474 1.00 83.37 C +ATOM 10202 CG LEU D 136 -63.258 -44.691 -85.539 1.00 80.22 C +ATOM 10203 CD1 LEU D 136 -61.803 -44.750 -85.981 1.00 71.10 C +ATOM 10204 CD2 LEU D 136 -63.763 -43.258 -85.526 1.00 80.67 C +ATOM 10205 N GLN D 137 -65.105 -48.449 -85.611 1.00 78.42 N +ATOM 10206 CA GLN D 137 -65.445 -49.439 -84.596 1.00 75.28 C +ATOM 10207 C GLN D 137 -64.462 -50.606 -84.621 1.00 72.19 C +ATOM 10208 O GLN D 137 -63.958 -51.026 -83.572 1.00 64.60 O +ATOM 10209 CB GLN D 137 -66.886 -49.923 -84.825 1.00 72.72 C +ATOM 10210 CG GLN D 137 -67.488 -50.818 -83.736 1.00 75.32 C +ATOM 10211 CD GLN D 137 -67.673 -50.113 -82.400 1.00 85.33 C +ATOM 10212 OE1 GLN D 137 -68.127 -48.970 -82.343 1.00 93.95 O +ATOM 10213 NE2 GLN D 137 -67.327 -50.801 -81.315 1.00 82.53 N +ATOM 10214 N SER D 138 -64.106 -51.078 -85.821 1.00 76.31 N +ATOM 10215 CA SER D 138 -63.224 -52.235 -85.946 1.00 75.35 C +ATOM 10216 C SER D 138 -61.779 -51.898 -85.613 1.00 71.84 C +ATOM 10217 O SER D 138 -61.061 -52.742 -85.066 1.00 75.38 O +ATOM 10218 CB SER D 138 -63.289 -52.800 -87.366 1.00 68.44 C +ATOM 10219 OG SER D 138 -64.616 -53.110 -87.750 1.00 69.64 O +ATOM 10220 N LEU D 139 -61.331 -50.689 -85.953 1.00 66.93 N +ATOM 10221 CA LEU D 139 -59.938 -50.325 -85.722 1.00 65.38 C +ATOM 10222 C LEU D 139 -59.579 -50.405 -84.243 1.00 73.84 C +ATOM 10223 O LEU D 139 -58.592 -51.048 -83.868 1.00 73.93 O +ATOM 10224 CB LEU D 139 -59.662 -48.929 -86.269 1.00 63.04 C +ATOM 10225 CG LEU D 139 -58.234 -48.467 -85.991 1.00 60.18 C +ATOM 10226 CD1 LEU D 139 -57.232 -49.227 -86.847 1.00 51.57 C +ATOM 10227 CD2 LEU D 139 -58.128 -46.976 -86.223 1.00 66.93 C +ATOM 10228 N PHE D 140 -60.362 -49.743 -83.385 1.00 78.03 N +ATOM 10229 CA PHE D 140 -60.110 -49.813 -81.948 1.00 76.21 C +ATOM 10230 C PHE D 140 -60.390 -51.201 -81.384 1.00 75.97 C +ATOM 10231 O PHE D 140 -59.948 -51.506 -80.268 1.00 76.79 O +ATOM 10232 CB PHE D 140 -60.941 -48.758 -81.211 1.00 75.87 C +ATOM 10233 CG PHE D 140 -60.610 -47.337 -81.603 1.00 78.82 C +ATOM 10234 CD1 PHE D 140 -59.347 -47.010 -82.077 1.00 69.31 C +ATOM 10235 CD2 PHE D 140 -61.560 -46.329 -81.496 1.00 90.38 C +ATOM 10236 CE1 PHE D 140 -59.040 -45.710 -82.443 1.00 70.28 C +ATOM 10237 CE2 PHE D 140 -61.257 -45.023 -81.858 1.00 83.73 C +ATOM 10238 CZ PHE D 140 -59.995 -44.716 -82.332 1.00 77.41 C +ATOM 10239 N GLU D 141 -61.101 -52.049 -82.131 1.00 76.51 N +ATOM 10240 CA GLU D 141 -61.331 -53.430 -81.728 1.00 79.71 C +ATOM 10241 C GLU D 141 -60.164 -54.351 -82.067 1.00 80.70 C +ATOM 10242 O GLU D 141 -60.153 -55.500 -81.610 1.00 83.07 O +ATOM 10243 CB GLU D 141 -62.603 -53.954 -82.404 1.00 79.60 C +ATOM 10244 CG GLU D 141 -63.850 -53.915 -81.535 1.00 84.05 C +ATOM 10245 CD GLU D 141 -65.109 -54.215 -82.336 1.00 93.52 C +ATOM 10246 OE1 GLU D 141 -65.335 -55.398 -82.664 1.00 94.08 O +ATOM 10247 OE2 GLU D 141 -65.885 -53.276 -82.620 1.00 85.02 O +ATOM 10248 N HIS D 142 -59.178 -53.869 -82.826 1.00 74.77 N +ATOM 10249 CA HIS D 142 -58.002 -54.655 -83.169 1.00 67.22 C +ATOM 10250 C HIS D 142 -57.191 -54.974 -81.914 1.00 67.82 C +ATOM 10251 O HIS D 142 -57.315 -54.288 -80.899 1.00 75.13 O +ATOM 10252 CB HIS D 142 -57.136 -53.885 -84.164 1.00 68.06 C +ATOM 10253 CG HIS D 142 -56.305 -54.754 -85.054 1.00 68.62 C +ATOM 10254 ND1 HIS D 142 -56.841 -55.489 -86.089 1.00 69.16 N +ATOM 10255 CD2 HIS D 142 -54.978 -55.027 -85.043 1.00 61.29 C +ATOM 10256 CE1 HIS D 142 -55.876 -56.164 -86.689 1.00 67.88 C +ATOM 10257 NE2 HIS D 142 -54.737 -55.902 -86.073 1.00 62.72 N +ATOM 10258 N PRO D 143 -56.348 -56.011 -81.955 1.00 66.50 N +ATOM 10259 CA PRO D 143 -55.419 -56.259 -80.842 1.00 71.76 C +ATOM 10260 C PRO D 143 -54.173 -55.389 -80.863 1.00 70.51 C +ATOM 10261 O PRO D 143 -53.347 -55.496 -79.948 1.00 66.10 O +ATOM 10262 CB PRO D 143 -55.052 -57.740 -81.022 1.00 66.26 C +ATOM 10263 CG PRO D 143 -55.227 -57.994 -82.465 1.00 74.83 C +ATOM 10264 CD PRO D 143 -56.403 -57.154 -82.883 1.00 74.34 C +ATOM 10265 N LEU D 144 -54.012 -54.537 -81.868 1.00 66.56 N +ATOM 10266 CA LEU D 144 -52.902 -53.596 -81.911 1.00 66.28 C +ATOM 10267 C LEU D 144 -53.254 -52.252 -81.295 1.00 63.85 C +ATOM 10268 O LEU D 144 -52.396 -51.363 -81.239 1.00 63.76 O +ATOM 10269 CB LEU D 144 -52.456 -53.371 -83.360 1.00 70.20 C +ATOM 10270 CG LEU D 144 -51.104 -53.911 -83.823 1.00 71.50 C +ATOM 10271 CD1 LEU D 144 -50.609 -53.066 -84.975 1.00 55.86 C +ATOM 10272 CD2 LEU D 144 -50.088 -53.944 -82.685 1.00 72.70 C +ATOM 10273 N TYR D 145 -54.487 -52.089 -80.819 1.00 68.48 N +ATOM 10274 CA TYR D 145 -54.945 -50.823 -80.261 1.00 69.80 C +ATOM 10275 C TYR D 145 -55.381 -50.960 -78.809 1.00 76.48 C +ATOM 10276 O TYR D 145 -55.928 -50.007 -78.240 1.00 74.66 O +ATOM 10277 CB TYR D 145 -56.087 -50.249 -81.106 1.00 61.91 C +ATOM 10278 CG TYR D 145 -55.607 -49.578 -82.371 1.00 65.19 C +ATOM 10279 CD1 TYR D 145 -54.821 -50.268 -83.283 1.00 61.79 C +ATOM 10280 CD2 TYR D 145 -55.917 -48.254 -82.645 1.00 67.93 C +ATOM 10281 CE1 TYR D 145 -54.367 -49.673 -84.432 1.00 55.75 C +ATOM 10282 CE2 TYR D 145 -55.462 -47.646 -83.807 1.00 63.30 C +ATOM 10283 CZ TYR D 145 -54.686 -48.368 -84.693 1.00 51.09 C +ATOM 10284 OH TYR D 145 -54.218 -47.796 -85.847 1.00 49.87 O +ATOM 10285 N ARG D 146 -55.182 -52.130 -78.207 1.00 76.09 N +ATOM 10286 CA ARG D 146 -55.511 -52.365 -76.812 1.00 74.73 C +ATOM 10287 C ARG D 146 -54.274 -52.517 -75.940 1.00 74.30 C +ATOM 10288 O ARG D 146 -54.408 -52.768 -74.737 1.00 74.36 O +ATOM 10289 CB ARG D 146 -56.409 -53.602 -76.693 1.00 78.95 C +ATOM 10290 CG ARG D 146 -57.297 -53.802 -77.914 1.00 75.82 C +ATOM 10291 CD ARG D 146 -58.457 -54.749 -77.648 1.00 90.87 C +ATOM 10292 NE ARG D 146 -59.562 -54.085 -76.960 1.00103.08 N +ATOM 10293 CZ ARG D 146 -60.811 -54.541 -76.930 1.00101.00 C +ATOM 10294 NH1 ARG D 146 -61.124 -55.669 -77.556 1.00102.02 N +ATOM 10295 NH2 ARG D 146 -61.747 -53.868 -76.273 1.00 87.66 N +ATOM 10296 N THR D 147 -53.077 -52.368 -76.512 1.00 69.33 N +ATOM 10297 CA THR D 147 -51.838 -52.414 -75.745 1.00 72.03 C +ATOM 10298 C THR D 147 -51.821 -51.333 -74.676 1.00 69.90 C +ATOM 10299 O THR D 147 -51.563 -50.164 -74.982 1.00 69.13 O +ATOM 10300 CB THR D 147 -50.629 -52.221 -76.660 1.00 71.93 C +ATOM 10301 OG1 THR D 147 -50.662 -53.192 -77.710 1.00 85.99 O +ATOM 10302 CG2 THR D 147 -49.337 -52.381 -75.865 1.00 62.66 C +ATOM 10303 N VAL D 148 -52.071 -51.702 -73.420 1.00 70.62 N +ATOM 10304 CA VAL D 148 -52.060 -50.705 -72.359 1.00 74.41 C +ATOM 10305 C VAL D 148 -50.628 -50.280 -72.066 1.00 77.24 C +ATOM 10306 O VAL D 148 -49.667 -51.035 -72.274 1.00 74.25 O +ATOM 10307 CB VAL D 148 -52.748 -51.221 -71.081 1.00 68.87 C +ATOM 10308 CG1 VAL D 148 -54.190 -51.610 -71.368 1.00 65.58 C +ATOM 10309 CG2 VAL D 148 -51.967 -52.383 -70.482 1.00 63.21 C +ATOM 10310 N LEU D 149 -50.488 -49.056 -71.563 1.00 81.34 N +ATOM 10311 CA LEU D 149 -49.203 -48.574 -71.115 1.00 74.98 C +ATOM 10312 C LEU D 149 -48.751 -49.387 -69.911 1.00 73.76 C +ATOM 10313 O LEU D 149 -49.566 -50.020 -69.235 1.00 73.45 O +ATOM 10314 CB LEU D 149 -49.286 -47.096 -70.732 1.00 76.76 C +ATOM 10315 CG LEU D 149 -49.944 -46.095 -71.685 1.00 77.29 C +ATOM 10316 CD1 LEU D 149 -50.040 -44.713 -71.036 1.00 60.43 C +ATOM 10317 CD2 LEU D 149 -49.203 -46.031 -73.018 1.00 82.48 C +ATOM 10318 N PRO D 150 -47.453 -49.389 -69.623 1.00 79.33 N +ATOM 10319 CA PRO D 150 -46.986 -49.946 -68.348 1.00 84.84 C +ATOM 10320 C PRO D 150 -47.640 -49.232 -67.173 1.00 78.76 C +ATOM 10321 O PRO D 150 -48.346 -48.232 -67.323 1.00 76.96 O +ATOM 10322 CB PRO D 150 -45.472 -49.712 -68.395 1.00 81.65 C +ATOM 10323 CG PRO D 150 -45.152 -49.694 -69.868 1.00 80.62 C +ATOM 10324 CD PRO D 150 -46.341 -49.052 -70.529 1.00 75.27 C +ATOM 10325 N ASP D 151 -47.418 -49.776 -65.978 1.00 81.68 N +ATOM 10326 CA ASP D 151 -47.945 -49.139 -64.781 1.00 85.63 C +ATOM 10327 C ASP D 151 -47.372 -47.732 -64.618 1.00 89.21 C +ATOM 10328 O ASP D 151 -46.396 -47.339 -65.265 1.00 91.22 O +ATOM 10329 CB ASP D 151 -47.644 -49.981 -63.542 1.00 85.54 C +ATOM 10330 CG ASP D 151 -48.496 -51.227 -63.467 1.00 85.17 C +ATOM 10331 OD1 ASP D 151 -49.601 -51.217 -64.053 1.00 80.31 O +ATOM 10332 OD2 ASP D 151 -48.068 -52.207 -62.822 1.00 83.93 O +ATOM 10333 N LEU D 152 -47.978 -46.980 -63.707 1.00 89.33 N +ATOM 10334 CA LEU D 152 -47.600 -45.601 -63.464 1.00 81.27 C +ATOM 10335 C LEU D 152 -47.000 -45.469 -62.072 1.00 83.50 C +ATOM 10336 O LEU D 152 -46.750 -46.459 -61.375 1.00 95.31 O +ATOM 10337 CB LEU D 152 -48.810 -44.682 -63.630 1.00 77.56 C +ATOM 10338 CG LEU D 152 -49.430 -44.632 -65.023 1.00 73.66 C +ATOM 10339 CD1 LEU D 152 -50.602 -45.599 -65.127 1.00 66.54 C +ATOM 10340 CD2 LEU D 152 -49.859 -43.216 -65.339 1.00 73.72 C +ATOM 10341 N THR D 153 -46.798 -44.226 -61.661 1.00 79.97 N +ATOM 10342 CA THR D 153 -46.207 -43.869 -60.382 1.00 87.41 C +ATOM 10343 C THR D 153 -46.387 -42.373 -60.217 1.00 95.75 C +ATOM 10344 O THR D 153 -46.492 -41.645 -61.208 1.00 97.67 O +ATOM 10345 CB THR D 153 -44.718 -44.245 -60.293 1.00 80.63 C +ATOM 10346 OG1 THR D 153 -44.140 -43.653 -59.122 1.00 81.22 O +ATOM 10347 CG2 THR D 153 -43.955 -43.770 -61.522 1.00 73.51 C +ATOM 10348 N GLU D 154 -46.481 -41.929 -58.961 1.00101.25 N +ATOM 10349 CA GLU D 154 -46.645 -40.503 -58.697 1.00 98.79 C +ATOM 10350 C GLU D 154 -45.587 -39.667 -59.409 1.00 95.27 C +ATOM 10351 O GLU D 154 -45.829 -38.486 -59.692 1.00 90.68 O +ATOM 10352 CB GLU D 154 -46.607 -40.235 -57.191 1.00102.37 C +ATOM 10353 CG GLU D 154 -47.813 -39.464 -56.668 1.00 98.52 C +ATOM 10354 CD GLU D 154 -47.430 -38.405 -55.647 1.00 98.74 C +ATOM 10355 OE1 GLU D 154 -48.112 -37.358 -55.592 1.00 88.62 O +ATOM 10356 OE2 GLU D 154 -46.443 -38.618 -54.907 1.00 94.80 O +ATOM 10357 N GLU D 155 -44.426 -40.256 -59.722 1.00 91.65 N +ATOM 10358 CA GLU D 155 -43.423 -39.563 -60.521 1.00 91.57 C +ATOM 10359 C GLU D 155 -43.826 -39.461 -61.991 1.00 89.61 C +ATOM 10360 O GLU D 155 -43.277 -38.622 -62.713 1.00 90.60 O +ATOM 10361 CB GLU D 155 -42.067 -40.274 -60.391 1.00 83.83 C +ATOM 10362 CG GLU D 155 -40.856 -39.392 -60.717 1.00102.34 C +ATOM 10363 CD GLU D 155 -40.392 -39.516 -62.164 1.00119.94 C +ATOM 10364 OE1 GLU D 155 -40.979 -40.331 -62.912 1.00112.27 O +ATOM 10365 OE2 GLU D 155 -39.456 -38.784 -62.557 1.00115.33 O +ATOM 10366 N ASP D 156 -44.783 -40.270 -62.449 1.00 85.46 N +ATOM 10367 CA ASP D 156 -45.226 -40.208 -63.839 1.00 84.34 C +ATOM 10368 C ASP D 156 -46.448 -39.323 -64.046 1.00 85.17 C +ATOM 10369 O ASP D 156 -46.788 -39.027 -65.199 1.00 73.82 O +ATOM 10370 CB ASP D 156 -45.523 -41.612 -64.375 1.00 87.86 C +ATOM 10371 CG ASP D 156 -44.264 -42.375 -64.723 1.00 88.38 C +ATOM 10372 OD1 ASP D 156 -43.238 -41.718 -65.004 1.00 83.32 O +ATOM 10373 OD2 ASP D 156 -44.305 -43.626 -64.740 1.00 88.17 O +ATOM 10374 N THR D 157 -47.131 -38.927 -62.974 1.00 90.99 N +ATOM 10375 CA THR D 157 -48.173 -37.916 -63.081 1.00 84.01 C +ATOM 10376 C THR D 157 -47.544 -36.545 -63.323 1.00 80.01 C +ATOM 10377 O THR D 157 -46.364 -36.309 -63.040 1.00 81.06 O +ATOM 10378 CB THR D 157 -49.043 -37.887 -61.822 1.00 80.44 C +ATOM 10379 OG1 THR D 157 -48.319 -38.443 -60.714 1.00 81.26 O +ATOM 10380 CG2 THR D 157 -50.329 -38.671 -62.042 1.00 66.39 C +ATOM 10381 N LEU D 158 -48.353 -35.621 -63.834 1.00 67.79 N +ATOM 10382 CA LEU D 158 -47.814 -34.304 -64.148 1.00 66.60 C +ATOM 10383 C LEU D 158 -47.772 -33.399 -62.923 1.00 69.55 C +ATOM 10384 O LEU D 158 -46.743 -32.779 -62.637 1.00 69.47 O +ATOM 10385 CB LEU D 158 -48.634 -33.655 -65.262 1.00 59.17 C +ATOM 10386 CG LEU D 158 -47.828 -33.197 -66.477 1.00 57.65 C +ATOM 10387 CD1 LEU D 158 -48.656 -32.232 -67.297 1.00 54.22 C +ATOM 10388 CD2 LEU D 158 -46.498 -32.575 -66.069 1.00 58.04 C +ATOM 10389 N PHE D 159 -48.879 -33.304 -62.195 1.00 65.24 N +ATOM 10390 CA PHE D 159 -48.960 -32.414 -61.049 1.00 57.92 C +ATOM 10391 C PHE D 159 -50.089 -32.881 -60.142 1.00 63.18 C +ATOM 10392 O PHE D 159 -51.024 -33.555 -60.583 1.00 62.09 O +ATOM 10393 CB PHE D 159 -49.183 -30.969 -61.499 1.00 54.90 C +ATOM 10394 CG PHE D 159 -50.261 -30.823 -62.537 1.00 54.83 C +ATOM 10395 CD1 PHE D 159 -51.596 -30.768 -62.167 1.00 58.79 C +ATOM 10396 CD2 PHE D 159 -49.943 -30.740 -63.882 1.00 54.92 C +ATOM 10397 CE1 PHE D 159 -52.592 -30.636 -63.117 1.00 57.78 C +ATOM 10398 CE2 PHE D 159 -50.939 -30.608 -64.840 1.00 57.65 C +ATOM 10399 CZ PHE D 159 -52.264 -30.555 -64.455 1.00 57.02 C +ATOM 10400 N ASN D 160 -50.001 -32.499 -58.871 1.00 63.74 N +ATOM 10401 CA ASN D 160 -50.999 -32.890 -57.876 1.00 60.96 C +ATOM 10402 C ASN D 160 -52.222 -32.005 -58.071 1.00 54.95 C +ATOM 10403 O ASN D 160 -52.282 -30.886 -57.564 1.00 59.68 O +ATOM 10404 CB ASN D 160 -50.443 -32.757 -56.463 1.00 58.99 C +ATOM 10405 CG ASN D 160 -49.269 -33.678 -56.205 1.00 70.30 C +ATOM 10406 OD1 ASN D 160 -49.193 -34.778 -56.757 1.00 75.28 O +ATOM 10407 ND2 ASN D 160 -48.329 -33.220 -55.383 1.00 69.69 N +ATOM 10408 N LEU D 161 -53.183 -32.503 -58.863 1.00 49.60 N +ATOM 10409 CA LEU D 161 -54.505 -31.909 -59.089 1.00 47.31 C +ATOM 10410 C LEU D 161 -54.926 -30.862 -58.063 1.00 57.58 C +ATOM 10411 O LEU D 161 -55.476 -29.815 -58.426 1.00 57.82 O +ATOM 10412 CB LEU D 161 -55.570 -33.006 -59.119 1.00 44.03 C +ATOM 10413 CG LEU D 161 -57.018 -32.573 -58.859 1.00 46.06 C +ATOM 10414 CD1 LEU D 161 -57.561 -31.686 -59.974 1.00 57.02 C +ATOM 10415 CD2 LEU D 161 -57.914 -33.790 -58.667 1.00 54.13 C +ATOM 10416 N ASN D 162 -54.679 -31.142 -56.780 1.00 69.53 N +ATOM 10417 CA ASN D 162 -54.962 -30.194 -55.710 1.00 68.68 C +ATOM 10418 C ASN D 162 -54.191 -28.886 -55.866 1.00 59.85 C +ATOM 10419 O ASN D 162 -54.536 -27.898 -55.207 1.00 59.40 O +ATOM 10420 CB ASN D 162 -54.629 -30.859 -54.363 1.00 63.87 C +ATOM 10421 CG ASN D 162 -55.135 -30.073 -53.170 1.00 71.01 C +ATOM 10422 OD1 ASN D 162 -56.170 -29.408 -53.242 1.00 78.80 O +ATOM 10423 ND2 ASN D 162 -54.424 -30.174 -52.050 1.00 72.20 N +ATOM 10424 N ALA D 163 -53.216 -28.828 -56.772 1.00 55.50 N +ATOM 10425 CA ALA D 163 -52.401 -27.643 -56.962 1.00 49.25 C +ATOM 10426 C ALA D 163 -52.750 -26.880 -58.222 1.00 48.34 C +ATOM 10427 O ALA D 163 -52.276 -25.753 -58.388 1.00 52.52 O +ATOM 10428 CB ALA D 163 -50.908 -28.013 -56.999 1.00 51.59 C +ATOM 10429 N GLU D 164 -53.564 -27.448 -59.106 1.00 48.27 N +ATOM 10430 CA GLU D 164 -54.080 -26.671 -60.221 1.00 45.62 C +ATOM 10431 C GLU D 164 -55.389 -25.983 -59.863 1.00 51.63 C +ATOM 10432 O GLU D 164 -55.666 -24.891 -60.370 1.00 54.85 O +ATOM 10433 CB GLU D 164 -54.258 -27.555 -61.463 1.00 47.10 C +ATOM 10434 CG GLU D 164 -54.798 -26.807 -62.687 1.00 57.79 C +ATOM 10435 CD GLU D 164 -54.907 -27.670 -63.939 1.00 67.14 C +ATOM 10436 OE1 GLU D 164 -55.005 -28.907 -63.803 1.00 72.73 O +ATOM 10437 OE2 GLU D 164 -54.924 -27.109 -65.059 1.00 61.13 O +ATOM 10438 N ILE D 165 -56.184 -26.573 -58.966 1.00 53.25 N +ATOM 10439 CA ILE D 165 -57.367 -25.892 -58.456 1.00 53.07 C +ATOM 10440 C ILE D 165 -56.989 -24.708 -57.584 1.00 51.94 C +ATOM 10441 O ILE D 165 -57.837 -23.852 -57.304 1.00 48.19 O +ATOM 10442 CB ILE D 165 -58.266 -26.888 -57.691 1.00 54.70 C +ATOM 10443 CG1 ILE D 165 -57.555 -27.473 -56.455 1.00 62.39 C +ATOM 10444 CG2 ILE D 165 -58.731 -28.001 -58.621 1.00 54.22 C +ATOM 10445 CD1 ILE D 165 -57.937 -26.834 -55.118 1.00 59.06 C +ATOM 10446 N ARG D 166 -55.706 -24.606 -57.217 1.00 50.60 N +ATOM 10447 CA ARG D 166 -55.171 -23.496 -56.442 1.00 49.20 C +ATOM 10448 C ARG D 166 -54.725 -22.348 -57.324 1.00 52.19 C +ATOM 10449 O ARG D 166 -54.397 -21.276 -56.810 1.00 59.05 O +ATOM 10450 CB ARG D 166 -53.986 -23.978 -55.567 1.00 55.83 C +ATOM 10451 CG ARG D 166 -53.291 -22.908 -54.710 1.00 55.61 C +ATOM 10452 CD ARG D 166 -52.103 -23.430 -53.920 1.00 58.88 C +ATOM 10453 NE ARG D 166 -52.506 -24.491 -53.000 1.00 71.90 N +ATOM 10454 CZ ARG D 166 -52.175 -25.776 -53.088 1.00 76.62 C +ATOM 10455 NH1 ARG D 166 -51.398 -26.211 -54.072 1.00 76.58 N +ATOM 10456 NH2 ARG D 166 -52.622 -26.626 -52.165 1.00 82.04 N +ATOM 10457 N LEU D 167 -54.765 -22.509 -58.639 1.00 47.93 N +ATOM 10458 CA LEU D 167 -54.423 -21.395 -59.503 1.00 42.25 C +ATOM 10459 C LEU D 167 -55.641 -20.653 -60.026 1.00 45.81 C +ATOM 10460 O LEU D 167 -55.516 -19.483 -60.402 1.00 49.54 O +ATOM 10461 CB LEU D 167 -53.573 -21.873 -60.683 1.00 38.00 C +ATOM 10462 CG LEU D 167 -52.063 -21.814 -60.455 1.00 38.00 C +ATOM 10463 CD1 LEU D 167 -51.649 -22.694 -59.302 1.00 42.25 C +ATOM 10464 CD2 LEU D 167 -51.314 -22.211 -61.711 1.00 45.05 C +ATOM 10465 N TYR D 168 -56.804 -21.267 -60.002 1.00 43.52 N +ATOM 10466 CA TYR D 168 -58.023 -20.681 -60.529 1.00 49.78 C +ATOM 10467 C TYR D 168 -58.823 -20.020 -59.417 1.00 53.43 C +ATOM 10468 O TYR D 168 -58.604 -20.302 -58.236 1.00 55.11 O +ATOM 10469 CB TYR D 168 -58.857 -21.764 -61.231 1.00 57.96 C +ATOM 10470 CG TYR D 168 -58.350 -22.152 -62.616 1.00 54.43 C +ATOM 10471 CD1 TYR D 168 -57.138 -22.818 -62.789 1.00 45.67 C +ATOM 10472 CD2 TYR D 168 -59.091 -21.841 -63.752 1.00 56.19 C +ATOM 10473 CE1 TYR D 168 -56.682 -23.160 -64.055 1.00 41.21 C +ATOM 10474 CE2 TYR D 168 -58.640 -22.176 -65.018 1.00 55.52 C +ATOM 10475 CZ TYR D 168 -57.436 -22.835 -65.164 1.00 52.61 C +ATOM 10476 OH TYR D 168 -56.994 -23.172 -66.425 1.00 54.56 O +ATOM 10477 N PRO D 169 -59.755 -19.096 -59.757 1.00 59.10 N +ATOM 10478 CA PRO D 169 -60.543 -18.417 -58.716 1.00 66.49 C +ATOM 10479 C PRO D 169 -61.390 -19.365 -57.883 1.00 68.58 C +ATOM 10480 O PRO D 169 -61.454 -20.566 -58.161 1.00 70.92 O +ATOM 10481 CB PRO D 169 -61.428 -17.452 -59.520 1.00 69.00 C +ATOM 10482 CG PRO D 169 -61.452 -18.008 -60.901 1.00 63.30 C +ATOM 10483 CD PRO D 169 -60.098 -18.603 -61.101 1.00 58.08 C +ATOM 10484 N LYS D 170 -62.071 -18.826 -56.870 1.00 69.78 N +ATOM 10485 CA LYS D 170 -62.907 -19.627 -55.982 1.00 76.78 C +ATOM 10486 C LYS D 170 -64.121 -20.239 -56.687 1.00 86.54 C +ATOM 10487 O LYS D 170 -64.871 -20.984 -56.041 1.00 85.76 O +ATOM 10488 CB LYS D 170 -63.355 -18.769 -54.796 1.00 74.46 C +ATOM 10489 CG LYS D 170 -62.199 -18.246 -53.950 1.00 72.10 C +ATOM 10490 CD LYS D 170 -62.664 -17.859 -52.554 1.00 74.87 C +ATOM 10491 CE LYS D 170 -62.968 -19.092 -51.704 1.00 83.02 C +ATOM 10492 NZ LYS D 170 -61.800 -20.009 -51.550 1.00 79.89 N +ATOM 10493 N ALA D 171 -64.325 -19.937 -57.972 1.00 82.66 N +ATOM 10494 CA ALA D 171 -65.381 -20.533 -58.792 1.00 76.31 C +ATOM 10495 C ALA D 171 -66.757 -20.182 -58.245 1.00 85.49 C +ATOM 10496 O ALA D 171 -66.983 -19.059 -57.797 1.00 85.72 O +ATOM 10497 CB ALA D 171 -65.210 -22.048 -58.887 1.00 82.61 C +ATOM 10498 N GLU D 197 -65.957 -36.299 -59.134 1.00104.46 N +ATOM 10499 CA GLU D 197 -65.445 -36.000 -60.469 1.00113.44 C +ATOM 10500 C GLU D 197 -66.405 -35.126 -61.272 1.00114.54 C +ATOM 10501 O GLU D 197 -66.688 -35.408 -62.439 1.00110.20 O +ATOM 10502 CB GLU D 197 -65.157 -37.295 -61.236 1.00103.88 C +ATOM 10503 CG GLU D 197 -63.911 -38.011 -60.755 1.00103.78 C +ATOM 10504 CD GLU D 197 -62.729 -37.068 -60.620 1.00113.48 C +ATOM 10505 OE1 GLU D 197 -62.379 -36.396 -61.615 1.00107.14 O +ATOM 10506 OE2 GLU D 197 -62.161 -36.987 -59.510 1.00117.66 O +ATOM 10507 N SER D 198 -66.903 -34.063 -60.642 1.00107.37 N +ATOM 10508 CA SER D 198 -67.742 -33.084 -61.315 1.00101.47 C +ATOM 10509 C SER D 198 -66.934 -31.921 -61.876 1.00 94.14 C +ATOM 10510 O SER D 198 -67.514 -30.897 -62.250 1.00 92.42 O +ATOM 10511 CB SER D 198 -68.820 -32.568 -60.359 1.00 93.37 C +ATOM 10512 OG SER D 198 -69.617 -31.576 -60.978 1.00102.09 O +ATOM 10513 N TYR D 199 -65.611 -32.059 -61.931 1.00 84.17 N +ATOM 10514 CA TYR D 199 -64.756 -31.037 -62.509 1.00 78.47 C +ATOM 10515 C TYR D 199 -64.983 -30.921 -64.017 1.00 82.75 C +ATOM 10516 O TYR D 199 -65.321 -31.905 -64.682 1.00 87.95 O +ATOM 10517 CB TYR D 199 -63.295 -31.361 -62.243 1.00 72.92 C +ATOM 10518 CG TYR D 199 -62.964 -31.517 -60.786 1.00 76.22 C +ATOM 10519 CD1 TYR D 199 -63.657 -30.804 -59.818 1.00 80.41 C +ATOM 10520 CD2 TYR D 199 -61.948 -32.368 -60.378 1.00 85.58 C +ATOM 10521 CE1 TYR D 199 -63.349 -30.942 -58.479 1.00 94.00 C +ATOM 10522 CE2 TYR D 199 -61.630 -32.512 -59.044 1.00 86.27 C +ATOM 10523 CZ TYR D 199 -62.333 -31.797 -58.098 1.00 90.87 C +ATOM 10524 OH TYR D 199 -62.020 -31.944 -56.766 1.00 88.12 O +ATOM 10525 N PRO D 200 -64.817 -29.722 -64.576 1.00 67.30 N +ATOM 10526 CA PRO D 200 -65.006 -29.549 -66.019 1.00 61.70 C +ATOM 10527 C PRO D 200 -64.073 -30.444 -66.825 1.00 67.84 C +ATOM 10528 O PRO D 200 -63.040 -30.918 -66.342 1.00 59.57 O +ATOM 10529 CB PRO D 200 -64.696 -28.066 -66.240 1.00 62.40 C +ATOM 10530 CG PRO D 200 -64.984 -27.426 -64.922 1.00 64.89 C +ATOM 10531 CD PRO D 200 -64.549 -28.440 -63.901 1.00 64.74 C +ATOM 10532 N ASN D 201 -64.479 -30.693 -68.076 1.00 73.39 N +ATOM 10533 CA ASN D 201 -63.758 -31.615 -68.949 1.00 58.59 C +ATOM 10534 C ASN D 201 -62.328 -31.165 -69.216 1.00 53.39 C +ATOM 10535 O ASN D 201 -61.439 -32.009 -69.386 1.00 53.39 O +ATOM 10536 CB ASN D 201 -64.505 -31.771 -70.271 1.00 55.38 C +ATOM 10537 CG ASN D 201 -65.888 -32.357 -70.091 1.00 61.61 C +ATOM 10538 OD1 ASN D 201 -66.162 -33.045 -69.104 1.00 63.65 O +ATOM 10539 ND2 ASN D 201 -66.771 -32.088 -71.046 1.00 62.98 N +ATOM 10540 N TRP D 202 -62.083 -29.852 -69.288 1.00 51.47 N +ATOM 10541 CA TRP D 202 -60.720 -29.380 -69.505 1.00 52.01 C +ATOM 10542 C TRP D 202 -59.815 -29.674 -68.319 1.00 51.94 C +ATOM 10543 O TRP D 202 -58.589 -29.671 -68.470 1.00 48.33 O +ATOM 10544 CB TRP D 202 -60.706 -27.877 -69.804 1.00 47.60 C +ATOM 10545 CG TRP D 202 -61.147 -27.017 -68.667 1.00 52.59 C +ATOM 10546 CD1 TRP D 202 -62.396 -26.517 -68.458 1.00 57.37 C +ATOM 10547 CD2 TRP D 202 -60.341 -26.552 -67.576 1.00 56.13 C +ATOM 10548 NE1 TRP D 202 -62.423 -25.766 -67.307 1.00 54.92 N +ATOM 10549 CE2 TRP D 202 -61.173 -25.774 -66.745 1.00 54.09 C +ATOM 10550 CE3 TRP D 202 -58.999 -26.718 -67.220 1.00 56.53 C +ATOM 10551 CZ2 TRP D 202 -60.706 -25.165 -65.585 1.00 51.69 C +ATOM 10552 CZ3 TRP D 202 -58.539 -26.115 -66.066 1.00 51.15 C +ATOM 10553 CH2 TRP D 202 -59.391 -25.353 -65.262 1.00 52.04 C +ATOM 10554 N LEU D 203 -60.387 -29.947 -67.149 1.00 56.29 N +ATOM 10555 CA LEU D 203 -59.580 -30.294 -65.990 1.00 56.19 C +ATOM 10556 C LEU D 203 -59.285 -31.787 -65.965 1.00 57.41 C +ATOM 10557 O LEU D 203 -58.134 -32.188 -65.766 1.00 55.47 O +ATOM 10558 CB LEU D 203 -60.287 -29.857 -64.701 1.00 55.13 C +ATOM 10559 CG LEU D 203 -59.526 -30.009 -63.377 1.00 55.07 C +ATOM 10560 CD1 LEU D 203 -58.059 -29.648 -63.520 1.00 50.82 C +ATOM 10561 CD2 LEU D 203 -60.169 -29.162 -62.294 1.00 58.23 C +ATOM 10562 N ARG D 204 -60.309 -32.618 -66.196 1.00 59.24 N +ATOM 10563 CA ARG D 204 -60.078 -34.050 -66.360 1.00 62.37 C +ATOM 10564 C ARG D 204 -59.084 -34.316 -67.485 1.00 60.52 C +ATOM 10565 O ARG D 204 -58.321 -35.288 -67.428 1.00 55.76 O +ATOM 10566 CB ARG D 204 -61.403 -34.773 -66.628 1.00 64.63 C +ATOM 10567 CG ARG D 204 -61.555 -36.126 -65.921 1.00 75.75 C +ATOM 10568 CD ARG D 204 -62.534 -36.037 -64.751 1.00 89.27 C +ATOM 10569 NE ARG D 204 -63.794 -35.407 -65.143 1.00 99.14 N +ATOM 10570 CZ ARG D 204 -64.909 -36.067 -65.446 1.00100.62 C +ATOM 10571 NH1 ARG D 204 -65.999 -35.396 -65.799 1.00 98.90 N +ATOM 10572 NH2 ARG D 204 -64.940 -37.393 -65.391 1.00 90.45 N +ATOM 10573 N PHE D 205 -59.073 -33.456 -68.505 1.00 56.03 N +ATOM 10574 CA PHE D 205 -58.079 -33.564 -69.564 1.00 51.93 C +ATOM 10575 C PHE D 205 -56.683 -33.240 -69.045 1.00 53.17 C +ATOM 10576 O PHE D 205 -55.708 -33.908 -69.409 1.00 53.15 O +ATOM 10577 CB PHE D 205 -58.471 -32.646 -70.724 1.00 51.49 C +ATOM 10578 CG PHE D 205 -57.344 -32.322 -71.664 1.00 53.14 C +ATOM 10579 CD1 PHE D 205 -56.682 -33.323 -72.352 1.00 54.01 C +ATOM 10580 CD2 PHE D 205 -56.967 -31.009 -71.880 1.00 52.73 C +ATOM 10581 CE1 PHE D 205 -55.652 -33.022 -73.218 1.00 52.04 C +ATOM 10582 CE2 PHE D 205 -55.942 -30.702 -72.748 1.00 50.56 C +ATOM 10583 CZ PHE D 205 -55.282 -31.710 -73.417 1.00 48.44 C +ATOM 10584 N HIS D 206 -56.566 -32.227 -68.185 1.00 54.39 N +ATOM 10585 CA HIS D 206 -55.245 -31.818 -67.715 1.00 62.86 C +ATOM 10586 C HIS D 206 -54.629 -32.858 -66.783 1.00 59.71 C +ATOM 10587 O HIS D 206 -53.449 -33.203 -66.925 1.00 58.63 O +ATOM 10588 CB HIS D 206 -55.330 -30.454 -67.023 1.00 65.51 C +ATOM 10589 CG HIS D 206 -55.370 -29.293 -67.971 1.00 62.51 C +ATOM 10590 ND1 HIS D 206 -56.279 -28.264 -67.852 1.00 65.75 N +ATOM 10591 CD2 HIS D 206 -54.600 -28.988 -69.043 1.00 57.28 C +ATOM 10592 CE1 HIS D 206 -56.079 -27.385 -68.819 1.00 62.59 C +ATOM 10593 NE2 HIS D 206 -55.062 -27.799 -69.553 1.00 56.66 N +ATOM 10594 N ILE D 207 -55.408 -33.380 -65.832 1.00 55.95 N +ATOM 10595 CA ILE D 207 -54.854 -34.307 -64.854 1.00 55.34 C +ATOM 10596 C ILE D 207 -54.480 -35.641 -65.483 1.00 56.03 C +ATOM 10597 O ILE D 207 -53.637 -36.364 -64.938 1.00 52.34 O +ATOM 10598 CB ILE D 207 -55.845 -34.510 -63.696 1.00 52.01 C +ATOM 10599 CG1 ILE D 207 -57.200 -34.977 -64.228 1.00 55.20 C +ATOM 10600 CG2 ILE D 207 -56.007 -33.221 -62.922 1.00 53.19 C +ATOM 10601 CD1 ILE D 207 -58.264 -35.140 -63.155 1.00 52.29 C +ATOM 10602 N GLY D 208 -55.071 -35.981 -66.629 1.00 56.09 N +ATOM 10603 CA GLY D 208 -54.778 -37.242 -67.286 1.00 56.82 C +ATOM 10604 C GLY D 208 -53.515 -37.263 -68.109 1.00 51.45 C +ATOM 10605 O GLY D 208 -53.132 -38.329 -68.598 1.00 51.33 O +ATOM 10606 N ILE D 209 -52.847 -36.123 -68.254 1.00 52.26 N +ATOM 10607 CA ILE D 209 -51.603 -36.043 -69.014 1.00 57.43 C +ATOM 10608 C ILE D 209 -50.493 -36.713 -68.219 1.00 58.68 C +ATOM 10609 O ILE D 209 -49.935 -36.122 -67.288 1.00 63.36 O +ATOM 10610 CB ILE D 209 -51.249 -34.584 -69.348 1.00 57.75 C +ATOM 10611 CG1 ILE D 209 -52.459 -33.872 -69.955 1.00 53.87 C +ATOM 10612 CG2 ILE D 209 -50.037 -34.527 -70.278 1.00 47.67 C +ATOM 10613 CD1 ILE D 209 -52.233 -32.406 -70.210 1.00 51.62 C +ATOM 10614 N ASN D 210 -50.193 -37.965 -68.553 1.00 61.95 N +ATOM 10615 CA ASN D 210 -49.131 -38.717 -67.909 1.00 61.31 C +ATOM 10616 C ASN D 210 -47.890 -38.760 -68.805 1.00 60.36 C +ATOM 10617 O ASN D 210 -47.830 -38.124 -69.862 1.00 55.64 O +ATOM 10618 CB ASN D 210 -49.620 -40.123 -67.568 1.00 61.78 C +ATOM 10619 CG ASN D 210 -49.906 -40.957 -68.807 1.00 67.82 C +ATOM 10620 OD1 ASN D 210 -50.556 -40.502 -69.743 1.00 69.33 O +ATOM 10621 ND2 ASN D 210 -49.400 -42.184 -68.822 1.00 69.17 N +ATOM 10622 N ARG D 211 -46.906 -39.564 -68.389 1.00 60.75 N +ATOM 10623 CA ARG D 211 -45.609 -39.615 -69.060 1.00 55.95 C +ATOM 10624 C ARG D 211 -45.725 -40.074 -70.508 1.00 52.01 C +ATOM 10625 O ARG D 211 -45.007 -39.573 -71.381 1.00 54.12 O +ATOM 10626 CB ARG D 211 -44.675 -40.544 -68.285 1.00 64.73 C +ATOM 10627 CG ARG D 211 -43.469 -41.020 -69.067 1.00 60.76 C +ATOM 10628 CD ARG D 211 -42.488 -41.727 -68.159 1.00 70.02 C +ATOM 10629 NE ARG D 211 -42.059 -40.877 -67.049 1.00 77.59 N +ATOM 10630 CZ ARG D 211 -40.952 -40.141 -67.049 1.00 77.49 C +ATOM 10631 NH1 ARG D 211 -40.151 -40.150 -68.109 1.00 71.44 N +ATOM 10632 NH2 ARG D 211 -40.646 -39.401 -65.987 1.00 70.36 N +ATOM 10633 N TYR D 212 -46.584 -41.055 -70.776 1.00 56.86 N +ATOM 10634 CA TYR D 212 -46.645 -41.683 -72.092 1.00 59.72 C +ATOM 10635 C TYR D 212 -47.656 -41.001 -73.004 1.00 57.07 C +ATOM 10636 O TYR D 212 -47.281 -40.269 -73.925 1.00 51.25 O +ATOM 10637 CB TYR D 212 -46.965 -43.172 -71.953 1.00 62.95 C +ATOM 10638 CG TYR D 212 -46.059 -43.890 -70.981 1.00 67.60 C +ATOM 10639 CD1 TYR D 212 -44.743 -44.190 -71.320 1.00 65.28 C +ATOM 10640 CD2 TYR D 212 -46.512 -44.260 -69.720 1.00 69.01 C +ATOM 10641 CE1 TYR D 212 -43.905 -44.842 -70.430 1.00 72.04 C +ATOM 10642 CE2 TYR D 212 -45.681 -44.914 -68.821 1.00 72.47 C +ATOM 10643 CZ TYR D 212 -44.378 -45.202 -69.182 1.00 77.67 C +ATOM 10644 OH TYR D 212 -43.547 -45.852 -68.294 1.00 75.92 O +ATOM 10645 N GLU D 213 -48.935 -41.279 -72.797 1.00 64.49 N +ATOM 10646 CA GLU D 213 -49.961 -40.660 -73.613 1.00 66.14 C +ATOM 10647 C GLU D 213 -50.300 -39.274 -73.069 1.00 62.64 C +ATOM 10648 O GLU D 213 -49.979 -38.927 -71.927 1.00 57.62 O +ATOM 10649 CB GLU D 213 -51.212 -41.538 -73.656 1.00 67.63 C +ATOM 10650 CG GLU D 213 -51.990 -41.570 -72.345 1.00 71.05 C +ATOM 10651 CD GLU D 213 -52.956 -42.736 -72.254 1.00 78.86 C +ATOM 10652 OE1 GLU D 213 -53.332 -43.288 -73.311 1.00 83.66 O +ATOM 10653 OE2 GLU D 213 -53.367 -43.078 -71.123 1.00 69.22 O +ATOM 10654 N LEU D 214 -50.892 -38.450 -73.934 1.00 57.48 N +ATOM 10655 CA LEU D 214 -51.482 -37.195 -73.493 1.00 51.98 C +ATOM 10656 C LEU D 214 -52.918 -37.380 -73.014 1.00 55.51 C +ATOM 10657 O LEU D 214 -53.452 -36.497 -72.332 1.00 53.45 O +ATOM 10658 CB LEU D 214 -51.435 -36.158 -74.621 1.00 51.54 C +ATOM 10659 CG LEU D 214 -51.729 -34.696 -74.268 1.00 51.16 C +ATOM 10660 CD1 LEU D 214 -50.441 -33.924 -74.108 1.00 48.91 C +ATOM 10661 CD2 LEU D 214 -52.615 -34.020 -75.293 1.00 53.90 C +ATOM 10662 N TYR D 215 -53.544 -38.508 -73.349 1.00 62.09 N +ATOM 10663 CA TYR D 215 -54.912 -38.822 -72.950 1.00 68.40 C +ATOM 10664 C TYR D 215 -55.173 -40.294 -73.240 1.00 68.19 C +ATOM 10665 O TYR D 215 -54.646 -40.844 -74.211 1.00 66.65 O +ATOM 10666 CB TYR D 215 -55.924 -37.938 -73.691 1.00 63.68 C +ATOM 10667 CG TYR D 215 -55.761 -37.940 -75.199 1.00 64.74 C +ATOM 10668 CD1 TYR D 215 -54.883 -37.061 -75.822 1.00 65.46 C +ATOM 10669 CD2 TYR D 215 -56.496 -38.806 -76.003 1.00 67.41 C +ATOM 10670 CE1 TYR D 215 -54.727 -37.054 -77.202 1.00 68.33 C +ATOM 10671 CE2 TYR D 215 -56.351 -38.801 -77.388 1.00 70.61 C +ATOM 10672 CZ TYR D 215 -55.461 -37.923 -77.980 1.00 68.00 C +ATOM 10673 OH TYR D 215 -55.298 -37.905 -79.349 1.00 57.74 O +ATOM 10674 N SER D 216 -55.976 -40.925 -72.378 1.00 64.66 N +ATOM 10675 CA SER D 216 -56.284 -42.344 -72.522 1.00 69.46 C +ATOM 10676 C SER D 216 -56.918 -42.634 -73.885 1.00 68.69 C +ATOM 10677 O SER D 216 -57.496 -41.757 -74.532 1.00 68.86 O +ATOM 10678 CB SER D 216 -57.202 -42.808 -71.393 1.00 68.76 C +ATOM 10679 OG SER D 216 -58.551 -42.490 -71.667 1.00 70.94 O +ATOM 10680 N ARG D 217 -56.814 -43.898 -74.311 1.00 65.50 N +ATOM 10681 CA ARG D 217 -57.225 -44.289 -75.662 1.00 70.21 C +ATOM 10682 C ARG D 217 -58.688 -43.950 -75.925 1.00 68.90 C +ATOM 10683 O ARG D 217 -59.014 -43.190 -76.845 1.00 69.86 O +ATOM 10684 CB ARG D 217 -56.972 -45.784 -75.874 1.00 74.50 C +ATOM 10685 CG ARG D 217 -55.942 -46.085 -76.953 1.00 66.44 C +ATOM 10686 CD ARG D 217 -55.267 -47.427 -76.721 1.00 70.02 C +ATOM 10687 NE ARG D 217 -53.887 -47.443 -77.208 1.00 86.59 N +ATOM 10688 CZ ARG D 217 -53.058 -48.479 -77.093 1.00 83.89 C +ATOM 10689 NH1 ARG D 217 -53.472 -49.592 -76.509 1.00 78.80 N +ATOM 10690 NH2 ARG D 217 -51.817 -48.400 -77.565 1.00 72.22 N +ATOM 10691 N HIS D 218 -59.586 -44.505 -75.129 1.00 63.48 N +ATOM 10692 CA HIS D 218 -61.012 -44.267 -75.290 1.00 77.58 C +ATOM 10693 C HIS D 218 -61.517 -43.558 -74.035 1.00 82.51 C +ATOM 10694 O HIS D 218 -62.279 -44.119 -73.246 1.00 87.29 O +ATOM 10695 CB HIS D 218 -61.759 -45.590 -75.561 1.00 86.14 C +ATOM 10696 CG HIS D 218 -62.942 -45.443 -76.471 1.00 98.82 C +ATOM 10697 ND1 HIS D 218 -63.963 -44.547 -76.228 1.00 99.65 N +ATOM 10698 CD2 HIS D 218 -63.272 -46.085 -77.617 1.00 93.31 C +ATOM 10699 CE1 HIS D 218 -64.867 -44.639 -77.188 1.00 91.22 C +ATOM 10700 NE2 HIS D 218 -64.472 -45.566 -78.043 1.00 95.14 N +ATOM 10701 N ASN D 219 -61.068 -42.320 -73.845 1.00 76.26 N +ATOM 10702 CA ASN D 219 -61.509 -41.531 -72.705 1.00 65.45 C +ATOM 10703 C ASN D 219 -62.920 -41.001 -72.949 1.00 66.98 C +ATOM 10704 O ASN D 219 -63.263 -40.648 -74.081 1.00 69.08 O +ATOM 10705 CB ASN D 219 -60.560 -40.364 -72.466 1.00 62.57 C +ATOM 10706 CG ASN D 219 -60.465 -39.985 -71.008 1.00 62.93 C +ATOM 10707 OD1 ASN D 219 -61.112 -39.041 -70.554 1.00 62.19 O +ATOM 10708 ND2 ASN D 219 -59.659 -40.724 -70.260 1.00 62.45 N +ATOM 10709 N PRO D 220 -63.756 -40.922 -71.910 1.00 66.88 N +ATOM 10710 CA PRO D 220 -65.077 -40.305 -72.079 1.00 66.62 C +ATOM 10711 C PRO D 220 -65.042 -38.795 -71.991 1.00 64.40 C +ATOM 10712 O PRO D 220 -66.020 -38.144 -72.386 1.00 59.68 O +ATOM 10713 CB PRO D 220 -65.889 -40.903 -70.924 1.00 73.34 C +ATOM 10714 CG PRO D 220 -64.880 -41.171 -69.861 1.00 76.32 C +ATOM 10715 CD PRO D 220 -63.552 -41.439 -70.546 1.00 73.79 C +ATOM 10716 N VAL D 221 -63.937 -38.224 -71.521 1.00 64.62 N +ATOM 10717 CA VAL D 221 -63.812 -36.779 -71.389 1.00 63.11 C +ATOM 10718 C VAL D 221 -63.271 -36.162 -72.668 1.00 61.22 C +ATOM 10719 O VAL D 221 -63.757 -35.120 -73.112 1.00 61.50 O +ATOM 10720 CB VAL D 221 -62.923 -36.436 -70.176 1.00 65.58 C +ATOM 10721 CG1 VAL D 221 -62.500 -34.974 -70.211 1.00 68.31 C +ATOM 10722 CG2 VAL D 221 -63.653 -36.754 -68.878 1.00 71.66 C +ATOM 10723 N ILE D 222 -62.268 -36.800 -73.276 1.00 59.40 N +ATOM 10724 CA ILE D 222 -61.742 -36.318 -74.549 1.00 59.22 C +ATOM 10725 C ILE D 222 -62.853 -36.243 -75.586 1.00 62.32 C +ATOM 10726 O ILE D 222 -62.868 -35.337 -76.429 1.00 63.16 O +ATOM 10727 CB ILE D 222 -60.580 -37.213 -75.021 1.00 57.46 C +ATOM 10728 CG1 ILE D 222 -59.478 -37.222 -73.968 1.00 62.16 C +ATOM 10729 CG2 ILE D 222 -60.013 -36.716 -76.341 1.00 55.14 C +ATOM 10730 CD1 ILE D 222 -58.853 -35.866 -73.763 1.00 66.11 C +ATOM 10731 N ALA D 223 -63.813 -37.167 -75.527 1.00 59.65 N +ATOM 10732 CA ALA D 223 -64.981 -37.068 -76.394 1.00 59.96 C +ATOM 10733 C ALA D 223 -65.840 -35.868 -76.020 1.00 61.95 C +ATOM 10734 O ALA D 223 -66.245 -35.087 -76.887 1.00 62.33 O +ATOM 10735 CB ALA D 223 -65.798 -38.358 -76.316 1.00 66.48 C +ATOM 10736 N ALA D 224 -66.110 -35.693 -74.725 1.00 66.79 N +ATOM 10737 CA ALA D 224 -66.940 -34.581 -74.274 1.00 68.06 C +ATOM 10738 C ALA D 224 -66.200 -33.247 -74.305 1.00 65.52 C +ATOM 10739 O ALA D 224 -66.837 -32.199 -74.460 1.00 66.21 O +ATOM 10740 CB ALA D 224 -67.468 -34.854 -72.867 1.00 69.97 C +ATOM 10741 N LEU D 225 -64.872 -33.257 -74.148 1.00 62.67 N +ATOM 10742 CA LEU D 225 -64.116 -32.010 -74.226 1.00 60.94 C +ATOM 10743 C LEU D 225 -64.274 -31.368 -75.596 1.00 58.08 C +ATOM 10744 O LEU D 225 -64.389 -30.141 -75.704 1.00 54.99 O +ATOM 10745 CB LEU D 225 -62.640 -32.269 -73.902 1.00 60.02 C +ATOM 10746 CG LEU D 225 -61.685 -31.101 -73.633 1.00 48.28 C +ATOM 10747 CD1 LEU D 225 -61.065 -30.562 -74.908 1.00 53.91 C +ATOM 10748 CD2 LEU D 225 -62.418 -29.994 -72.906 1.00 47.09 C +ATOM 10749 N LEU D 226 -64.294 -32.185 -76.655 1.00 59.58 N +ATOM 10750 CA LEU D 226 -64.540 -31.663 -77.995 1.00 59.40 C +ATOM 10751 C LEU D 226 -65.923 -31.035 -78.093 1.00 59.48 C +ATOM 10752 O LEU D 226 -66.103 -30.013 -78.764 1.00 60.01 O +ATOM 10753 CB LEU D 226 -64.377 -32.776 -79.034 1.00 53.94 C +ATOM 10754 CG LEU D 226 -62.983 -33.381 -79.238 1.00 56.95 C +ATOM 10755 CD1 LEU D 226 -63.029 -34.509 -80.265 1.00 59.00 C +ATOM 10756 CD2 LEU D 226 -61.969 -32.319 -79.649 1.00 52.85 C +ATOM 10757 N ARG D 227 -66.913 -31.631 -77.422 1.00 59.77 N +ATOM 10758 CA ARG D 227 -68.275 -31.108 -77.474 1.00 60.12 C +ATOM 10759 C ARG D 227 -68.379 -29.747 -76.799 1.00 62.72 C +ATOM 10760 O ARG D 227 -69.163 -28.895 -77.232 1.00 64.54 O +ATOM 10761 CB ARG D 227 -69.241 -32.095 -76.824 1.00 59.85 C +ATOM 10762 CG ARG D 227 -69.274 -33.456 -77.479 1.00 63.72 C +ATOM 10763 CD ARG D 227 -69.962 -34.460 -76.579 1.00 76.27 C +ATOM 10764 NE ARG D 227 -70.029 -35.781 -77.194 1.00 84.13 N +ATOM 10765 CZ ARG D 227 -70.480 -36.868 -76.577 1.00 85.39 C +ATOM 10766 NH1 ARG D 227 -70.509 -38.027 -77.221 1.00 90.18 N +ATOM 10767 NH2 ARG D 227 -70.895 -36.796 -75.318 1.00 76.86 N +ATOM 10768 N ASP D 228 -67.616 -29.531 -75.726 1.00 63.86 N +ATOM 10769 CA ASP D 228 -67.676 -28.254 -75.021 1.00 66.71 C +ATOM 10770 C ASP D 228 -67.229 -27.105 -75.919 1.00 66.71 C +ATOM 10771 O ASP D 228 -67.921 -26.089 -76.032 1.00 67.24 O +ATOM 10772 CB ASP D 228 -66.833 -28.317 -73.746 1.00 65.80 C +ATOM 10773 CG ASP D 228 -67.508 -29.119 -72.645 1.00 69.12 C +ATOM 10774 OD1 ASP D 228 -68.736 -29.340 -72.741 1.00 66.64 O +ATOM 10775 OD2 ASP D 228 -66.815 -29.527 -71.686 1.00 65.75 O +ATOM 10776 N LEU D 229 -66.081 -27.258 -76.583 1.00 65.80 N +ATOM 10777 CA LEU D 229 -65.582 -26.195 -77.451 1.00 57.21 C +ATOM 10778 C LEU D 229 -66.554 -25.889 -78.586 1.00 58.79 C +ATOM 10779 O LEU D 229 -66.622 -24.743 -79.049 1.00 56.15 O +ATOM 10780 CB LEU D 229 -64.208 -26.577 -78.007 1.00 50.29 C +ATOM 10781 CG LEU D 229 -63.220 -27.086 -76.953 1.00 49.17 C +ATOM 10782 CD1 LEU D 229 -61.855 -27.420 -77.548 1.00 46.88 C +ATOM 10783 CD2 LEU D 229 -63.086 -26.078 -75.831 1.00 53.57 C +ATOM 10784 N LEU D 230 -67.328 -26.886 -79.027 1.00 59.61 N +ATOM 10785 CA LEU D 230 -68.262 -26.678 -80.132 1.00 59.12 C +ATOM 10786 C LEU D 230 -69.361 -25.692 -79.761 1.00 62.39 C +ATOM 10787 O LEU D 230 -69.802 -24.905 -80.607 1.00 65.08 O +ATOM 10788 CB LEU D 230 -68.892 -28.007 -80.557 1.00 57.49 C +ATOM 10789 CG LEU D 230 -68.000 -29.126 -81.096 1.00 70.71 C +ATOM 10790 CD1 LEU D 230 -68.798 -30.407 -81.338 1.00 73.60 C +ATOM 10791 CD2 LEU D 230 -67.313 -28.688 -82.363 1.00 71.51 C +ATOM 10792 N SER D 231 -69.830 -25.735 -78.509 1.00 64.02 N +ATOM 10793 CA SER D 231 -71.066 -25.062 -78.126 1.00 65.81 C +ATOM 10794 C SER D 231 -70.993 -24.245 -76.840 1.00 60.35 C +ATOM 10795 O SER D 231 -71.968 -23.551 -76.530 1.00 59.90 O +ATOM 10796 CB SER D 231 -72.214 -26.079 -78.004 1.00 65.74 C +ATOM 10797 OG SER D 231 -71.868 -27.145 -77.143 1.00 72.22 O +ATOM 10798 N GLN D 232 -69.918 -24.337 -76.060 1.00 57.72 N +ATOM 10799 CA GLN D 232 -69.837 -23.563 -74.828 1.00 54.20 C +ATOM 10800 C GLN D 232 -69.798 -22.071 -75.146 1.00 55.97 C +ATOM 10801 O GLN D 232 -69.342 -21.656 -76.215 1.00 57.38 O +ATOM 10802 CB GLN D 232 -68.595 -23.956 -74.032 1.00 57.81 C +ATOM 10803 CG GLN D 232 -68.648 -23.598 -72.565 1.00 62.30 C +ATOM 10804 CD GLN D 232 -69.456 -24.594 -71.758 1.00 63.83 C +ATOM 10805 OE1 GLN D 232 -70.620 -24.860 -72.058 1.00 77.85 O +ATOM 10806 NE2 GLN D 232 -68.837 -25.157 -70.729 1.00 55.86 N +ATOM 10807 N LYS D 233 -70.271 -21.260 -74.202 1.00 61.32 N +ATOM 10808 CA LYS D 233 -70.384 -19.823 -74.428 1.00 64.44 C +ATOM 10809 C LYS D 233 -69.027 -19.147 -74.305 1.00 57.23 C +ATOM 10810 O LYS D 233 -68.227 -19.480 -73.424 1.00 53.28 O +ATOM 10811 CB LYS D 233 -71.366 -19.187 -73.438 1.00 71.57 C +ATOM 10812 CG LYS D 233 -71.643 -17.696 -73.696 1.00 67.49 C +ATOM 10813 CD LYS D 233 -72.754 -17.147 -72.789 1.00 69.38 C +ATOM 10814 CE LYS D 233 -73.104 -15.694 -73.125 1.00 53.63 C +ATOM 10815 NZ LYS D 233 -74.258 -15.175 -72.328 1.00 38.00 N +ATOM 10816 N ILE D 234 -68.769 -18.202 -75.202 1.00 55.92 N +ATOM 10817 CA ILE D 234 -67.511 -17.464 -75.197 1.00 57.92 C +ATOM 10818 C ILE D 234 -67.599 -16.367 -74.145 1.00 55.76 C +ATOM 10819 O ILE D 234 -68.533 -15.558 -74.159 1.00 53.52 O +ATOM 10820 CB ILE D 234 -67.205 -16.868 -76.576 1.00 61.32 C +ATOM 10821 CG1 ILE D 234 -67.095 -17.957 -77.643 1.00 57.41 C +ATOM 10822 CG2 ILE D 234 -65.896 -16.105 -76.517 1.00 59.29 C +ATOM 10823 CD1 ILE D 234 -65.984 -18.943 -77.399 1.00 59.94 C +ATOM 10824 N SER D 235 -66.647 -16.360 -73.211 1.00 58.84 N +ATOM 10825 CA SER D 235 -66.572 -15.345 -72.164 1.00 56.17 C +ATOM 10826 C SER D 235 -65.594 -14.229 -72.508 1.00 53.61 C +ATOM 10827 O SER D 235 -65.944 -13.050 -72.408 1.00 54.44 O +ATOM 10828 CB SER D 235 -66.190 -15.976 -70.822 1.00 56.62 C +ATOM 10829 OG SER D 235 -64.837 -16.378 -70.824 1.00 64.01 O +ATOM 10830 N SER D 236 -64.361 -14.572 -72.885 1.00 56.75 N +ATOM 10831 CA SER D 236 -63.367 -13.567 -73.234 1.00 60.26 C +ATOM 10832 C SER D 236 -62.508 -14.030 -74.401 1.00 62.45 C +ATOM 10833 O SER D 236 -62.188 -15.215 -74.532 1.00 61.67 O +ATOM 10834 CB SER D 236 -62.452 -13.229 -72.058 1.00 56.83 C +ATOM 10835 OG SER D 236 -61.492 -12.267 -72.459 1.00 60.59 O +ATOM 10836 N VAL D 237 -62.120 -13.064 -75.235 1.00 60.79 N +ATOM 10837 CA VAL D 237 -61.300 -13.295 -76.419 1.00 49.52 C +ATOM 10838 C VAL D 237 -60.107 -12.354 -76.373 1.00 46.21 C +ATOM 10839 O VAL D 237 -60.273 -11.142 -76.204 1.00 52.36 O +ATOM 10840 CB VAL D 237 -62.098 -13.068 -77.714 1.00 47.84 C +ATOM 10841 CG1 VAL D 237 -61.215 -13.305 -78.919 1.00 54.08 C +ATOM 10842 CG2 VAL D 237 -63.314 -13.960 -77.746 1.00 53.59 C +ATOM 10843 N GLY D 238 -58.919 -12.899 -76.571 1.00 41.78 N +ATOM 10844 CA GLY D 238 -57.709 -12.101 -76.544 1.00 40.18 C +ATOM 10845 C GLY D 238 -56.741 -12.557 -77.610 1.00 43.84 C +ATOM 10846 O GLY D 238 -56.687 -13.734 -77.970 1.00 48.22 O +ATOM 10847 N MET D 239 -55.974 -11.605 -78.117 1.00 48.35 N +ATOM 10848 CA MET D 239 -54.994 -11.888 -79.150 1.00 60.44 C +ATOM 10849 C MET D 239 -53.673 -12.313 -78.514 1.00 69.39 C +ATOM 10850 O MET D 239 -53.231 -11.721 -77.524 1.00 68.34 O +ATOM 10851 CB MET D 239 -54.801 -10.652 -80.032 1.00 63.40 C +ATOM 10852 CG MET D 239 -53.898 -10.856 -81.230 1.00 73.06 C +ATOM 10853 SD MET D 239 -53.457 -9.302 -82.039 1.00 68.07 S +ATOM 10854 CE MET D 239 -55.048 -8.700 -82.541 1.00 46.99 C +ATOM 10855 N LYS D 240 -53.062 -13.363 -79.067 1.00 67.53 N +ATOM 10856 CA LYS D 240 -51.732 -13.772 -78.634 1.00 69.60 C +ATOM 10857 C LYS D 240 -50.673 -12.943 -79.349 1.00 87.22 C +ATOM 10858 O LYS D 240 -50.867 -12.493 -80.482 1.00 87.46 O +ATOM 10859 CB LYS D 240 -51.480 -15.256 -78.918 1.00 58.08 C +ATOM 10860 CG LYS D 240 -50.167 -15.781 -78.339 1.00 67.64 C +ATOM 10861 CD LYS D 240 -49.878 -17.203 -78.774 1.00 76.30 C +ATOM 10862 CE LYS D 240 -50.510 -18.217 -77.817 1.00 69.52 C +ATOM 10863 NZ LYS D 240 -49.844 -18.316 -76.481 1.00 38.00 N +ATOM 10864 N SER D 241 -49.541 -12.753 -78.683 1.00 82.41 N +ATOM 10865 CA SER D 241 -48.427 -12.020 -79.259 1.00 89.53 C +ATOM 10866 C SER D 241 -47.243 -12.957 -79.481 1.00 92.00 C +ATOM 10867 O SER D 241 -47.188 -14.068 -78.943 1.00 72.38 O +ATOM 10868 CB SER D 241 -48.027 -10.842 -78.362 1.00 84.86 C +ATOM 10869 OG SER D 241 -47.123 -9.978 -79.029 1.00 95.91 O +ATOM 10870 N GLY D 242 -46.314 -12.506 -80.330 1.00100.88 N +ATOM 10871 CA GLY D 242 -45.044 -13.173 -80.547 1.00102.43 C +ATOM 10872 C GLY D 242 -45.057 -14.349 -81.502 1.00106.42 C +ATOM 10873 O GLY D 242 -43.984 -14.888 -81.806 1.00107.48 O +ATOM 10874 N GLY D 243 -46.224 -14.768 -81.991 1.00106.60 N +ATOM 10875 CA GLY D 243 -46.314 -15.905 -82.879 1.00 90.30 C +ATOM 10876 C GLY D 243 -46.087 -15.533 -84.332 1.00 84.72 C +ATOM 10877 O GLY D 243 -45.828 -14.384 -84.687 1.00 74.37 O +ATOM 10878 N THR D 244 -46.173 -16.554 -85.184 1.00 92.69 N +ATOM 10879 CA THR D 244 -46.025 -16.342 -86.620 1.00 75.52 C +ATOM 10880 C THR D 244 -47.248 -15.639 -87.201 1.00 63.88 C +ATOM 10881 O THR D 244 -47.147 -14.535 -87.746 1.00 56.45 O +ATOM 10882 CB THR D 244 -45.786 -17.680 -87.322 1.00 74.70 C +ATOM 10883 OG1 THR D 244 -45.767 -18.740 -86.352 1.00 75.26 O +ATOM 10884 CG2 THR D 244 -44.461 -17.655 -88.068 1.00 70.67 C +ATOM 10885 N GLN D 245 -48.414 -16.260 -87.083 1.00 63.74 N +ATOM 10886 CA GLN D 245 -49.657 -15.742 -87.635 1.00 52.65 C +ATOM 10887 C GLN D 245 -50.650 -15.486 -86.503 1.00 66.48 C +ATOM 10888 O GLN D 245 -50.332 -15.656 -85.322 1.00 72.73 O +ATOM 10889 CB GLN D 245 -50.210 -16.719 -88.669 1.00 57.67 C +ATOM 10890 CG GLN D 245 -49.649 -16.482 -90.059 1.00 59.34 C +ATOM 10891 CD GLN D 245 -49.797 -17.690 -90.957 1.00 57.74 C +ATOM 10892 OE1 GLN D 245 -50.874 -18.284 -91.047 1.00 62.63 O +ATOM 10893 NE2 GLN D 245 -48.712 -18.065 -91.628 1.00 49.56 N +ATOM 10894 N LEU D 246 -51.873 -15.096 -86.870 1.00 63.41 N +ATOM 10895 CA LEU D 246 -52.883 -14.701 -85.889 1.00 60.93 C +ATOM 10896 C LEU D 246 -53.460 -15.916 -85.171 1.00 54.94 C +ATOM 10897 O LEU D 246 -54.018 -16.814 -85.809 1.00 54.22 O +ATOM 10898 CB LEU D 246 -54.014 -13.922 -86.555 1.00 48.31 C +ATOM 10899 CG LEU D 246 -55.061 -13.452 -85.544 1.00 38.16 C +ATOM 10900 CD1 LEU D 246 -54.541 -12.225 -84.823 1.00 48.16 C +ATOM 10901 CD2 LEU D 246 -56.403 -13.170 -86.195 1.00 38.00 C +ATOM 10902 N LYS D 247 -53.358 -15.922 -83.844 1.00 52.18 N +ATOM 10903 CA LYS D 247 -53.968 -16.955 -83.016 1.00 54.17 C +ATOM 10904 C LYS D 247 -54.565 -16.284 -81.786 1.00 59.05 C +ATOM 10905 O LYS D 247 -53.882 -15.516 -81.101 1.00 63.61 O +ATOM 10906 CB LYS D 247 -52.953 -18.046 -82.629 1.00 53.38 C +ATOM 10907 CG LYS D 247 -51.514 -17.561 -82.480 1.00 67.62 C +ATOM 10908 CD LYS D 247 -50.501 -18.706 -82.565 1.00 73.16 C +ATOM 10909 CE LYS D 247 -49.081 -18.173 -82.786 1.00 84.16 C +ATOM 10910 NZ LYS D 247 -48.020 -19.229 -82.819 1.00 95.17 N +ATOM 10911 N LEU D 248 -55.849 -16.541 -81.540 1.00 54.24 N +ATOM 10912 CA LEU D 248 -56.609 -15.900 -80.476 1.00 46.95 C +ATOM 10913 C LEU D 248 -56.826 -16.843 -79.297 1.00 46.78 C +ATOM 10914 O LEU D 248 -56.978 -18.056 -79.466 1.00 46.31 O +ATOM 10915 CB LEU D 248 -57.964 -15.428 -81.005 1.00 38.00 C +ATOM 10916 CG LEU D 248 -58.054 -13.970 -81.435 1.00 38.00 C +ATOM 10917 CD1 LEU D 248 -56.844 -13.573 -82.245 1.00 42.03 C +ATOM 10918 CD2 LEU D 248 -59.328 -13.759 -82.235 1.00 38.00 C +ATOM 10919 N ILE D 249 -56.880 -16.267 -78.100 1.00 43.37 N +ATOM 10920 CA ILE D 249 -57.116 -17.025 -76.878 1.00 40.22 C +ATOM 10921 C ILE D 249 -58.570 -16.851 -76.476 1.00 43.61 C +ATOM 10922 O ILE D 249 -59.032 -15.728 -76.243 1.00 45.38 O +ATOM 10923 CB ILE D 249 -56.186 -16.580 -75.745 1.00 38.00 C +ATOM 10924 CG1 ILE D 249 -54.781 -17.111 -75.997 1.00 46.91 C +ATOM 10925 CG2 ILE D 249 -56.722 -17.075 -74.413 1.00 38.00 C +ATOM 10926 CD1 ILE D 249 -53.957 -16.215 -76.867 1.00 41.75 C +ATOM 10927 N MET D 250 -59.270 -17.966 -76.342 1.00 49.61 N +ATOM 10928 CA MET D 250 -60.668 -17.977 -75.957 1.00 50.32 C +ATOM 10929 C MET D 250 -60.786 -18.394 -74.503 1.00 60.67 C +ATOM 10930 O MET D 250 -60.028 -19.243 -74.031 1.00 58.96 O +ATOM 10931 CB MET D 250 -61.459 -18.942 -76.837 1.00 49.85 C +ATOM 10932 CG MET D 250 -61.291 -18.671 -78.303 1.00 45.42 C +ATOM 10933 SD MET D 250 -62.572 -17.547 -78.838 1.00 45.25 S +ATOM 10934 CE MET D 250 -61.925 -17.044 -80.421 1.00 52.33 C +ATOM 10935 N SER D 251 -61.726 -17.780 -73.793 1.00 67.99 N +ATOM 10936 CA SER D 251 -62.088 -18.187 -72.444 1.00 63.60 C +ATOM 10937 C SER D 251 -63.575 -18.502 -72.419 1.00 64.39 C +ATOM 10938 O SER D 251 -64.373 -17.827 -73.079 1.00 61.74 O +ATOM 10939 CB SER D 251 -61.746 -17.105 -71.419 1.00 55.37 C +ATOM 10940 OG SER D 251 -60.343 -16.936 -71.315 1.00 52.06 O +ATOM 10941 N PHE D 252 -63.941 -19.535 -71.668 1.00 64.22 N +ATOM 10942 CA PHE D 252 -65.291 -20.074 -71.691 1.00 61.01 C +ATOM 10943 C PHE D 252 -65.986 -19.889 -70.351 1.00 60.14 C +ATOM 10944 O PHE D 252 -65.404 -19.422 -69.368 1.00 58.56 O +ATOM 10945 CB PHE D 252 -65.272 -21.551 -72.081 1.00 61.49 C +ATOM 10946 CG PHE D 252 -64.731 -21.795 -73.453 1.00 59.74 C +ATOM 10947 CD1 PHE D 252 -65.551 -21.684 -74.562 1.00 56.47 C +ATOM 10948 CD2 PHE D 252 -63.400 -22.117 -73.636 1.00 59.36 C +ATOM 10949 CE1 PHE D 252 -65.057 -21.907 -75.825 1.00 55.89 C +ATOM 10950 CE2 PHE D 252 -62.897 -22.336 -74.900 1.00 63.81 C +ATOM 10951 CZ PHE D 252 -63.729 -22.231 -75.997 1.00 62.91 C +ATOM 10952 N GLN D 253 -67.266 -20.266 -70.342 1.00 59.10 N +ATOM 10953 CA GLN D 253 -68.099 -20.135 -69.155 1.00 65.34 C +ATOM 10954 C GLN D 253 -67.619 -21.031 -68.015 1.00 67.97 C +ATOM 10955 O GLN D 253 -67.904 -20.739 -66.848 1.00 70.74 O +ATOM 10956 CB GLN D 253 -69.549 -20.453 -69.527 1.00 65.73 C +ATOM 10957 CG GLN D 253 -70.590 -20.004 -68.522 1.00 76.80 C +ATOM 10958 CD GLN D 253 -72.004 -20.300 -68.991 1.00 85.51 C +ATOM 10959 OE1 GLN D 253 -72.785 -19.387 -69.274 1.00 85.44 O +ATOM 10960 NE2 GLN D 253 -72.336 -21.582 -69.090 1.00 80.81 N +ATOM 10961 N ASN D 254 -66.886 -22.101 -68.324 1.00 65.66 N +ATOM 10962 CA ASN D 254 -66.356 -23.020 -67.326 1.00 60.87 C +ATOM 10963 C ASN D 254 -64.878 -22.774 -67.049 1.00 56.82 C +ATOM 10964 O ASN D 254 -64.137 -23.720 -66.764 1.00 52.47 O +ATOM 10965 CB ASN D 254 -66.570 -24.460 -67.777 1.00 62.35 C +ATOM 10966 CG ASN D 254 -66.076 -24.694 -69.179 1.00 65.22 C +ATOM 10967 OD1 ASN D 254 -66.717 -24.288 -70.147 1.00 67.26 O +ATOM 10968 ND2 ASN D 254 -64.929 -25.342 -69.303 1.00 62.27 N +ATOM 10969 N TYR D 255 -64.432 -21.527 -67.191 1.00 62.22 N +ATOM 10970 CA TYR D 255 -63.083 -21.117 -66.814 1.00 67.44 C +ATOM 10971 C TYR D 255 -62.001 -21.784 -67.662 1.00 66.05 C +ATOM 10972 O TYR D 255 -60.809 -21.517 -67.482 1.00 60.93 O +ATOM 10973 CB TYR D 255 -62.829 -21.403 -65.335 1.00 63.75 C +ATOM 10974 CG TYR D 255 -63.749 -20.647 -64.412 1.00 72.32 C +ATOM 10975 CD1 TYR D 255 -65.001 -21.149 -64.068 1.00 84.86 C +ATOM 10976 CD2 TYR D 255 -63.362 -19.426 -63.883 1.00 68.23 C +ATOM 10977 CE1 TYR D 255 -65.842 -20.452 -63.212 1.00 92.76 C +ATOM 10978 CE2 TYR D 255 -64.192 -18.723 -63.034 1.00 81.93 C +ATOM 10979 CZ TYR D 255 -65.431 -19.239 -62.700 1.00 98.36 C +ATOM 10980 OH TYR D 255 -66.256 -18.535 -61.850 1.00103.78 O +ATOM 10981 N GLY D 256 -62.409 -22.681 -68.555 1.00 64.51 N +ATOM 10982 CA GLY D 256 -61.478 -23.243 -69.502 1.00 63.37 C +ATOM 10983 C GLY D 256 -61.113 -22.259 -70.596 1.00 58.63 C +ATOM 10984 O GLY D 256 -61.834 -21.303 -70.887 1.00 57.84 O +ATOM 10985 N GLN D 257 -59.961 -22.507 -71.213 1.00 56.55 N +ATOM 10986 CA GLN D 257 -59.477 -21.674 -72.300 1.00 52.09 C +ATOM 10987 C GLN D 257 -58.941 -22.561 -73.419 1.00 53.21 C +ATOM 10988 O GLN D 257 -58.725 -23.765 -73.246 1.00 53.44 O +ATOM 10989 CB GLN D 257 -58.411 -20.686 -71.815 1.00 49.43 C +ATOM 10990 CG GLN D 257 -57.652 -21.121 -70.578 1.00 48.81 C +ATOM 10991 CD GLN D 257 -56.783 -20.002 -70.037 1.00 51.10 C +ATOM 10992 OE1 GLN D 257 -57.191 -18.834 -69.999 1.00 39.63 O +ATOM 10993 NE2 GLN D 257 -55.563 -20.347 -69.648 1.00 54.43 N +ATOM 10994 N ALA D 258 -58.724 -21.942 -74.578 1.00 52.11 N +ATOM 10995 CA ALA D 258 -58.308 -22.660 -75.776 1.00 49.17 C +ATOM 10996 C ALA D 258 -57.662 -21.688 -76.752 1.00 47.96 C +ATOM 10997 O ALA D 258 -57.891 -20.478 -76.689 1.00 54.32 O +ATOM 10998 CB ALA D 258 -59.496 -23.365 -76.435 1.00 46.19 C +ATOM 10999 N LEU D 259 -56.833 -22.232 -77.643 1.00 47.35 N +ATOM 11000 CA LEU D 259 -56.281 -21.466 -78.752 1.00 43.02 C +ATOM 11001 C LEU D 259 -57.245 -21.500 -79.929 1.00 46.57 C +ATOM 11002 O LEU D 259 -57.971 -22.475 -80.131 1.00 51.52 O +ATOM 11003 CB LEU D 259 -54.927 -22.021 -79.195 1.00 38.96 C +ATOM 11004 CG LEU D 259 -53.868 -20.955 -79.457 1.00 40.01 C +ATOM 11005 CD1 LEU D 259 -53.528 -20.299 -78.133 1.00 54.22 C +ATOM 11006 CD2 LEU D 259 -52.623 -21.534 -80.113 1.00 38.00 C +ATOM 11007 N PHE D 260 -57.222 -20.441 -80.732 1.00 44.58 N +ATOM 11008 CA PHE D 260 -58.178 -20.303 -81.822 1.00 40.31 C +ATOM 11009 C PHE D 260 -57.466 -19.795 -83.064 1.00 41.46 C +ATOM 11010 O PHE D 260 -56.935 -18.681 -83.062 1.00 41.05 O +ATOM 11011 CB PHE D 260 -59.311 -19.350 -81.438 1.00 38.00 C +ATOM 11012 CG PHE D 260 -60.275 -19.098 -82.549 1.00 41.12 C +ATOM 11013 CD1 PHE D 260 -61.346 -19.946 -82.755 1.00 43.02 C +ATOM 11014 CD2 PHE D 260 -60.101 -18.024 -83.406 1.00 44.58 C +ATOM 11015 CE1 PHE D 260 -62.242 -19.717 -83.781 1.00 44.26 C +ATOM 11016 CE2 PHE D 260 -60.988 -17.796 -84.440 1.00 45.00 C +ATOM 11017 CZ PHE D 260 -62.059 -18.643 -84.627 1.00 44.66 C +ATOM 11018 N LYS D 261 -57.491 -20.591 -84.128 1.00 42.90 N +ATOM 11019 CA LYS D 261 -56.980 -20.187 -85.422 1.00 41.99 C +ATOM 11020 C LYS D 261 -58.136 -20.114 -86.414 1.00 44.73 C +ATOM 11021 O LYS D 261 -58.902 -21.077 -86.542 1.00 47.68 O +ATOM 11022 CB LYS D 261 -55.890 -21.171 -85.925 1.00 39.22 C +ATOM 11023 CG LYS D 261 -54.641 -21.179 -85.040 1.00 46.40 C +ATOM 11024 CD LYS D 261 -53.469 -21.979 -85.610 1.00 52.53 C +ATOM 11025 CE LYS D 261 -52.228 -21.832 -84.716 1.00 56.65 C +ATOM 11026 NZ LYS D 261 -51.061 -22.645 -85.163 1.00 56.87 N +ATOM 11027 N PRO D 262 -58.323 -18.987 -87.094 1.00 42.98 N +ATOM 11028 CA PRO D 262 -59.495 -18.831 -87.965 1.00 47.18 C +ATOM 11029 C PRO D 262 -59.364 -19.590 -89.277 1.00 55.63 C +ATOM 11030 O PRO D 262 -58.408 -20.344 -89.484 1.00 57.26 O +ATOM 11031 CB PRO D 262 -59.552 -17.317 -88.217 1.00 44.88 C +ATOM 11032 CG PRO D 262 -58.523 -16.706 -87.302 1.00 42.99 C +ATOM 11033 CD PRO D 262 -57.511 -17.767 -87.046 1.00 39.28 C +ATOM 11034 N MET D 263 -60.332 -19.378 -90.173 1.00 55.38 N +ATOM 11035 CA MET D 263 -60.367 -20.096 -91.443 1.00 50.98 C +ATOM 11036 C MET D 263 -59.155 -19.769 -92.305 1.00 56.61 C +ATOM 11037 O MET D 263 -58.409 -20.667 -92.710 1.00 62.43 O +ATOM 11038 CB MET D 263 -61.654 -19.770 -92.191 1.00 53.17 C +ATOM 11039 CG MET D 263 -61.745 -20.436 -93.540 1.00 57.46 C +ATOM 11040 SD MET D 263 -63.422 -20.967 -93.912 1.00 59.99 S +ATOM 11041 CE MET D 263 -63.100 -22.269 -95.104 1.00 56.55 C +ATOM 11042 N LYS D 264 -58.995 -18.491 -92.661 1.00 54.52 N +ATOM 11043 CA LYS D 264 -57.859 -17.978 -93.427 1.00 59.39 C +ATOM 11044 C LYS D 264 -57.884 -18.396 -94.897 1.00 62.21 C +ATOM 11045 O LYS D 264 -57.582 -17.580 -95.773 1.00 60.05 O +ATOM 11046 CB LYS D 264 -56.531 -18.396 -92.774 1.00 56.80 C +ATOM 11047 CG LYS D 264 -55.353 -17.514 -93.170 1.00 61.32 C +ATOM 11048 CD LYS D 264 -55.498 -16.096 -92.626 1.00 78.10 C +ATOM 11049 CE LYS D 264 -54.944 -15.025 -93.591 1.00 77.98 C +ATOM 11050 NZ LYS D 264 -55.685 -14.887 -94.899 1.00 56.66 N +ATOM 11051 N GLN D 265 -58.253 -19.645 -95.187 1.00 68.29 N +ATOM 11052 CA GLN D 265 -58.316 -20.130 -96.561 1.00 69.63 C +ATOM 11053 C GLN D 265 -59.371 -21.226 -96.691 1.00 69.63 C +ATOM 11054 O GLN D 265 -59.745 -21.880 -95.712 1.00 70.17 O +ATOM 11055 CB GLN D 265 -56.948 -20.652 -97.039 1.00 65.49 C +ATOM 11056 CG GLN D 265 -56.303 -19.825 -98.141 1.00 66.59 C +ATOM 11057 CD GLN D 265 -57.268 -19.548 -99.288 1.00 87.62 C +ATOM 11058 OE1 GLN D 265 -58.114 -20.386 -99.625 1.00 83.39 O +ATOM 11059 NE2 GLN D 265 -57.145 -18.371 -99.896 1.00 85.86 N +ATOM 11060 N THR D 266 -59.830 -21.429 -97.930 1.00 63.29 N +ATOM 11061 CA THR D 266 -60.901 -22.364 -98.251 1.00 56.63 C +ATOM 11062 C THR D 266 -60.374 -23.796 -98.314 1.00 62.26 C +ATOM 11063 O THR D 266 -59.199 -24.072 -98.062 1.00 72.33 O +ATOM 11064 CB THR D 266 -61.548 -21.994 -99.578 1.00 50.65 C +ATOM 11065 OG1 THR D 266 -60.630 -22.283-100.639 1.00 48.50 O +ATOM 11066 CG2 THR D 266 -61.895 -20.526 -99.596 1.00 58.77 C +ATOM 11067 N ARG D 267 -61.253 -24.726 -98.681 1.00 59.11 N +ATOM 11068 CA ARG D 267 -60.892 -26.139 -98.684 1.00 57.98 C +ATOM 11069 C ARG D 267 -60.247 -26.563-100.000 1.00 57.63 C +ATOM 11070 O ARG D 267 -59.211 -27.235-100.002 1.00 50.45 O +ATOM 11071 CB ARG D 267 -62.131 -26.997 -98.404 1.00 60.04 C +ATOM 11072 CG ARG D 267 -62.319 -27.379 -96.938 1.00 59.13 C +ATOM 11073 CD ARG D 267 -62.420 -26.142 -96.052 1.00 54.61 C +ATOM 11074 NE ARG D 267 -62.825 -26.457 -94.685 1.00 52.93 N +ATOM 11075 CZ ARG D 267 -64.085 -26.478 -94.261 1.00 57.57 C +ATOM 11076 NH1 ARG D 267 -65.079 -26.201 -95.094 1.00 63.01 N +ATOM 11077 NH2 ARG D 267 -64.355 -26.774 -93.000 1.00 55.67 N +ATOM 11078 N GLU D 268 -60.842 -26.164-101.123 1.00 62.73 N +ATOM 11079 CA GLU D 268 -60.389 -26.601-102.435 1.00 55.76 C +ATOM 11080 C GLU D 268 -59.131 -25.884-102.897 1.00 51.15 C +ATOM 11081 O GLU D 268 -58.691 -26.112-104.029 1.00 50.38 O +ATOM 11082 CB GLU D 268 -61.494 -26.398-103.482 1.00 57.34 C +ATOM 11083 CG GLU D 268 -62.793 -27.155-103.213 1.00 63.85 C +ATOM 11084 CD GLU D 268 -63.751 -26.393-102.311 1.00 68.50 C +ATOM 11085 OE1 GLU D 268 -63.463 -25.218-101.988 1.00 65.11 O +ATOM 11086 OE2 GLU D 268 -64.787 -26.977-101.919 1.00 66.69 O +ATOM 11087 N GLN D 269 -58.545 -25.033-102.063 1.00 54.49 N +ATOM 11088 CA GLN D 269 -57.372 -24.275-102.460 1.00 60.94 C +ATOM 11089 C GLN D 269 -56.086 -25.013-102.101 1.00 58.99 C +ATOM 11090 O GLN D 269 -56.012 -25.730-101.099 1.00 55.24 O +ATOM 11091 CB GLN D 269 -57.384 -22.890-101.810 1.00 59.83 C +ATOM 11092 CG GLN D 269 -58.032 -21.823-102.677 1.00 66.42 C +ATOM 11093 CD GLN D 269 -57.452 -20.446-102.431 1.00 84.03 C +ATOM 11094 OE1 GLN D 269 -56.278 -20.311-102.079 1.00 88.46 O +ATOM 11095 NE2 GLN D 269 -58.269 -19.412-102.616 1.00 90.38 N +ATOM 11096 N GLU D 270 -55.069 -24.831-102.941 1.00 55.11 N +ATOM 11097 CA GLU D 270 -53.744 -25.384-102.718 1.00 50.84 C +ATOM 11098 C GLU D 270 -52.741 -24.255-102.523 1.00 49.34 C +ATOM 11099 O GLU D 270 -52.878 -23.174-103.101 1.00 46.80 O +ATOM 11100 CB GLU D 270 -53.289 -26.260-103.891 1.00 53.81 C +ATOM 11101 CG GLU D 270 -53.816 -27.688-103.896 1.00 55.66 C +ATOM 11102 CD GLU D 270 -52.981 -28.603-104.782 1.00 64.92 C +ATOM 11103 OE1 GLU D 270 -51.747 -28.649-104.588 1.00 70.42 O +ATOM 11104 OE2 GLU D 270 -53.548 -29.255-105.687 1.00 64.06 O +ATOM 11105 N THR D 271 -51.722 -24.529-101.720 1.00 48.69 N +ATOM 11106 CA THR D 271 -50.627 -23.588-101.542 1.00 46.52 C +ATOM 11107 C THR D 271 -49.894 -23.371-102.862 1.00 49.79 C +ATOM 11108 O THR D 271 -49.565 -24.349-103.548 1.00 56.72 O +ATOM 11109 CB THR D 271 -49.653 -24.103-100.488 1.00 46.28 C +ATOM 11110 OG1 THR D 271 -50.325 -24.205 -99.227 1.00 47.11 O +ATOM 11111 CG2 THR D 271 -48.470 -23.168-100.361 1.00 49.12 C +ATOM 11112 N PRO D 272 -49.645 -22.126-103.263 1.00 48.43 N +ATOM 11113 CA PRO D 272 -48.902 -21.866-104.504 1.00 52.43 C +ATOM 11114 C PRO D 272 -47.570 -22.595-104.511 1.00 55.41 C +ATOM 11115 O PRO D 272 -46.900 -22.702-103.472 1.00 52.59 O +ATOM 11116 CB PRO D 272 -48.705 -20.344-104.481 1.00 51.92 C +ATOM 11117 CG PRO D 272 -49.845 -19.841-103.667 1.00 47.21 C +ATOM 11118 CD PRO D 272 -50.108 -20.883-102.624 1.00 47.41 C +ATOM 11119 N PRO D 273 -47.159 -23.129-105.663 1.00 54.14 N +ATOM 11120 CA PRO D 273 -45.906 -23.898-105.707 1.00 51.70 C +ATOM 11121 C PRO D 273 -44.681 -23.067-105.388 1.00 51.19 C +ATOM 11122 O PRO D 273 -43.667 -23.625-104.950 1.00 50.90 O +ATOM 11123 CB PRO D 273 -45.867 -24.425-107.149 1.00 60.75 C +ATOM 11124 CG PRO D 273 -47.280 -24.306-107.655 1.00 60.49 C +ATOM 11125 CD PRO D 273 -47.835 -23.099-106.970 1.00 58.36 C +ATOM 11126 N ASP D 274 -44.748 -21.751-105.572 1.00 51.54 N +ATOM 11127 CA ASP D 274 -43.613 -20.862-105.370 1.00 51.28 C +ATOM 11128 C ASP D 274 -43.506 -20.357-103.939 1.00 48.82 C +ATOM 11129 O ASP D 274 -42.626 -19.542-103.645 1.00 43.14 O +ATOM 11130 CB ASP D 274 -43.720 -19.667-106.318 1.00 49.69 C +ATOM 11131 CG ASP D 274 -44.074 -20.076-107.725 1.00 52.37 C +ATOM 11132 OD1 ASP D 274 -45.262 -20.387-107.969 1.00 52.37 O +ATOM 11133 OD2 ASP D 274 -43.170 -20.082-108.584 1.00 55.23 O +ATOM 11134 N PHE D 275 -44.358 -20.842-103.040 1.00 50.33 N +ATOM 11135 CA PHE D 275 -44.360 -20.395-101.655 1.00 51.30 C +ATOM 11136 C PHE D 275 -43.344 -21.192-100.856 1.00 51.37 C +ATOM 11137 O PHE D 275 -43.322 -22.424-100.924 1.00 54.13 O +ATOM 11138 CB PHE D 275 -45.747 -20.559-101.034 1.00 50.14 C +ATOM 11139 CG PHE D 275 -46.629 -19.354-101.187 1.00 49.31 C +ATOM 11140 CD1 PHE D 275 -46.220 -18.272-101.948 1.00 51.84 C +ATOM 11141 CD2 PHE D 275 -47.867 -19.305-100.573 1.00 46.01 C +ATOM 11142 CE1 PHE D 275 -47.029 -17.166-102.092 1.00 52.60 C +ATOM 11143 CE2 PHE D 275 -48.681 -18.205-100.714 1.00 47.26 C +ATOM 11144 CZ PHE D 275 -48.263 -17.133-101.473 1.00 54.25 C +ATOM 11145 N PHE D 276 -42.510 -20.486-100.100 1.00 49.19 N +ATOM 11146 CA PHE D 276 -41.606 -21.160 -99.189 1.00 51.40 C +ATOM 11147 C PHE D 276 -42.393 -21.824 -98.059 1.00 54.20 C +ATOM 11148 O PHE D 276 -43.565 -21.520 -97.816 1.00 55.17 O +ATOM 11149 CB PHE D 276 -40.585 -20.173 -98.621 1.00 52.46 C +ATOM 11150 CG PHE D 276 -39.441 -19.860 -99.557 1.00 56.92 C +ATOM 11151 CD1 PHE D 276 -38.410 -20.770 -99.745 1.00 57.48 C +ATOM 11152 CD2 PHE D 276 -39.384 -18.647-100.231 1.00 56.67 C +ATOM 11153 CE1 PHE D 276 -37.352 -20.480-100.595 1.00 55.07 C +ATOM 11154 CE2 PHE D 276 -38.324 -18.353-101.083 1.00 52.34 C +ATOM 11155 CZ PHE D 276 -37.311 -19.272-101.263 1.00 49.46 C +ATOM 11156 N TYR D 277 -41.728 -22.757 -97.371 1.00 55.12 N +ATOM 11157 CA TYR D 277 -42.345 -23.433 -96.233 1.00 54.10 C +ATOM 11158 C TYR D 277 -42.698 -22.464 -95.116 1.00 50.65 C +ATOM 11159 O TYR D 277 -43.632 -22.718 -94.347 1.00 50.08 O +ATOM 11160 CB TYR D 277 -41.420 -24.530 -95.706 1.00 58.39 C +ATOM 11161 CG TYR D 277 -39.948 -24.177 -95.748 1.00 68.33 C +ATOM 11162 CD1 TYR D 277 -39.328 -23.517 -94.691 1.00 56.47 C +ATOM 11163 CD2 TYR D 277 -39.178 -24.499 -96.861 1.00 78.41 C +ATOM 11164 CE1 TYR D 277 -37.974 -23.200 -94.746 1.00 61.62 C +ATOM 11165 CE2 TYR D 277 -37.832 -24.183 -96.925 1.00 73.39 C +ATOM 11166 CZ TYR D 277 -37.234 -23.535 -95.867 1.00 72.57 C +ATOM 11167 OH TYR D 277 -35.894 -23.228 -95.944 1.00 74.97 O +ATOM 11168 N PHE D 278 -41.961 -21.365 -94.997 1.00 55.76 N +ATOM 11169 CA PHE D 278 -42.252 -20.351 -93.996 1.00 58.17 C +ATOM 11170 C PHE D 278 -43.202 -19.275 -94.499 1.00 51.69 C +ATOM 11171 O PHE D 278 -43.359 -18.249 -93.835 1.00 53.81 O +ATOM 11172 CB PHE D 278 -40.955 -19.706 -93.497 1.00 62.32 C +ATOM 11173 CG PHE D 278 -40.102 -19.108 -94.587 1.00 58.82 C +ATOM 11174 CD1 PHE D 278 -40.294 -17.800 -95.006 1.00 53.79 C +ATOM 11175 CD2 PHE D 278 -39.088 -19.850 -95.173 1.00 62.39 C +ATOM 11176 CE1 PHE D 278 -39.502 -17.252 -95.998 1.00 57.94 C +ATOM 11177 CE2 PHE D 278 -38.292 -19.306 -96.163 1.00 61.74 C +ATOM 11178 CZ PHE D 278 -38.499 -18.008 -96.576 1.00 65.82 C +ATOM 11179 N SER D 279 -43.839 -19.482 -95.648 1.00 50.66 N +ATOM 11180 CA SER D 279 -44.844 -18.556 -96.141 1.00 48.39 C +ATOM 11181 C SER D 279 -46.227 -19.172 -96.234 1.00 51.52 C +ATOM 11182 O SER D 279 -47.181 -18.462 -96.574 1.00 53.72 O +ATOM 11183 CB SER D 279 -44.439 -18.015 -97.516 1.00 54.78 C +ATOM 11184 OG SER D 279 -43.211 -17.316 -97.436 1.00 69.16 O +ATOM 11185 N ASP D 280 -46.363 -20.465 -95.958 1.00 52.82 N +ATOM 11186 CA ASP D 280 -47.649 -21.133 -96.066 1.00 52.72 C +ATOM 11187 C ASP D 280 -48.607 -20.633 -94.985 1.00 53.12 C +ATOM 11188 O ASP D 280 -48.199 -20.129 -93.935 1.00 51.73 O +ATOM 11189 CB ASP D 280 -47.476 -22.647 -95.962 1.00 51.86 C +ATOM 11190 CG ASP D 280 -48.584 -23.409 -96.666 1.00 55.16 C +ATOM 11191 OD1 ASP D 280 -49.738 -22.922 -96.684 1.00 51.06 O +ATOM 11192 OD2 ASP D 280 -48.301 -24.507 -97.189 1.00 57.79 O +ATOM 11193 N PHE D 281 -49.900 -20.772 -95.262 1.00 52.56 N +ATOM 11194 CA PHE D 281 -50.928 -20.347 -94.325 1.00 56.28 C +ATOM 11195 C PHE D 281 -51.112 -21.365 -93.202 1.00 55.83 C +ATOM 11196 O PHE D 281 -50.948 -22.574 -93.393 1.00 56.75 O +ATOM 11197 CB PHE D 281 -52.264 -20.154 -95.043 1.00 59.70 C +ATOM 11198 CG PHE D 281 -52.264 -19.039 -96.047 1.00 66.67 C +ATOM 11199 CD1 PHE D 281 -52.075 -17.729 -95.643 1.00 68.48 C +ATOM 11200 CD2 PHE D 281 -52.513 -19.293 -97.386 1.00 64.13 C +ATOM 11201 CE1 PHE D 281 -52.094 -16.698 -96.561 1.00 66.63 C +ATOM 11202 CE2 PHE D 281 -52.536 -18.265 -98.307 1.00 60.40 C +ATOM 11203 CZ PHE D 281 -52.326 -16.967 -97.893 1.00 63.06 C +ATOM 11204 N GLU D 282 -51.473 -20.865 -92.022 1.00 55.37 N +ATOM 11205 CA GLU D 282 -51.914 -21.715 -90.921 1.00 52.37 C +ATOM 11206 C GLU D 282 -53.432 -21.801 -90.994 1.00 51.50 C +ATOM 11207 O GLU D 282 -54.124 -20.793 -90.818 1.00 57.00 O +ATOM 11208 CB GLU D 282 -51.457 -21.159 -89.573 1.00 51.81 C +ATOM 11209 CG GLU D 282 -49.956 -21.271 -89.326 1.00 59.76 C +ATOM 11210 CD GLU D 282 -49.576 -21.051 -87.872 1.00 62.31 C +ATOM 11211 OE1 GLU D 282 -50.175 -20.168 -87.226 1.00 69.35 O +ATOM 11212 OE2 GLU D 282 -48.662 -21.748 -87.382 1.00 69.33 O +ATOM 11213 N ARG D 283 -53.955 -22.991 -91.271 1.00 44.42 N +ATOM 11214 CA ARG D 283 -55.380 -23.159 -91.510 1.00 48.93 C +ATOM 11215 C ARG D 283 -56.009 -24.080 -90.472 1.00 47.60 C +ATOM 11216 O ARG D 283 -55.383 -25.041 -90.014 1.00 46.03 O +ATOM 11217 CB ARG D 283 -55.635 -23.694 -92.919 1.00 54.16 C +ATOM 11218 CG ARG D 283 -55.124 -25.091 -93.163 1.00 55.29 C +ATOM 11219 CD ARG D 283 -54.556 -25.225 -94.567 1.00 57.33 C +ATOM 11220 NE ARG D 283 -53.096 -25.223 -94.584 1.00 51.09 N +ATOM 11221 CZ ARG D 283 -52.363 -24.941 -95.655 1.00 48.13 C +ATOM 11222 NH1 ARG D 283 -52.951 -24.620 -96.799 1.00 56.42 N +ATOM 11223 NH2 ARG D 283 -51.042 -24.980 -95.581 1.00 43.91 N +ATOM 11224 N HIS D 284 -57.255 -23.762 -90.102 1.00 48.29 N +ATOM 11225 CA HIS D 284 -57.999 -24.583 -89.152 1.00 46.21 C +ATOM 11226 C HIS D 284 -58.188 -26.007 -89.649 1.00 48.87 C +ATOM 11227 O HIS D 284 -58.262 -26.935 -88.836 1.00 49.06 O +ATOM 11228 CB HIS D 284 -59.364 -23.958 -88.856 1.00 48.42 C +ATOM 11229 CG HIS D 284 -60.262 -23.850 -90.052 1.00 53.74 C +ATOM 11230 ND1 HIS D 284 -59.805 -23.498 -91.305 1.00 53.41 N +ATOM 11231 CD2 HIS D 284 -61.594 -24.059 -90.185 1.00 56.64 C +ATOM 11232 CE1 HIS D 284 -60.818 -23.482 -92.153 1.00 56.81 C +ATOM 11233 NE2 HIS D 284 -61.915 -23.821 -91.499 1.00 55.90 N +ATOM 11234 N ASN D 285 -58.274 -26.197 -90.970 1.00 49.40 N +ATOM 11235 CA ASN D 285 -58.386 -27.542 -91.529 1.00 46.94 C +ATOM 11236 C ASN D 285 -57.306 -28.449 -90.965 1.00 50.96 C +ATOM 11237 O ASN D 285 -57.588 -29.543 -90.463 1.00 51.97 O +ATOM 11238 CB ASN D 285 -58.273 -27.496 -93.054 1.00 48.06 C +ATOM 11239 CG ASN D 285 -59.120 -26.412 -93.676 1.00 65.58 C +ATOM 11240 OD1 ASN D 285 -60.308 -26.291 -93.376 1.00 79.68 O +ATOM 11241 ND2 ASN D 285 -58.512 -25.609 -94.549 1.00 58.38 N +ATOM 11242 N ALA D 286 -56.056 -27.985 -91.008 1.00 50.25 N +ATOM 11243 CA ALA D 286 -54.943 -28.829 -90.600 1.00 47.81 C +ATOM 11244 C ALA D 286 -55.003 -29.135 -89.114 1.00 48.47 C +ATOM 11245 O ALA D 286 -54.778 -30.279 -88.705 1.00 50.89 O +ATOM 11246 CB ALA D 286 -53.619 -28.156 -90.953 1.00 49.19 C +ATOM 11247 N GLU D 287 -55.320 -28.132 -88.293 1.00 46.66 N +ATOM 11248 CA GLU D 287 -55.341 -28.345 -86.850 1.00 50.80 C +ATOM 11249 C GLU D 287 -56.337 -29.435 -86.468 1.00 48.59 C +ATOM 11250 O GLU D 287 -55.996 -30.370 -85.735 1.00 44.03 O +ATOM 11251 CB GLU D 287 -55.642 -27.030 -86.129 1.00 51.98 C +ATOM 11252 CG GLU D 287 -54.530 -25.981 -86.244 1.00 53.30 C +ATOM 11253 CD GLU D 287 -53.310 -26.290 -85.369 1.00 61.15 C +ATOM 11254 OE1 GLU D 287 -53.373 -27.234 -84.550 1.00 62.14 O +ATOM 11255 OE2 GLU D 287 -52.288 -25.576 -85.488 1.00 59.23 O +ATOM 11256 N ILE D 288 -57.569 -29.346 -86.975 1.00 45.76 N +ATOM 11257 CA ILE D 288 -58.574 -30.352 -86.648 1.00 43.61 C +ATOM 11258 C ILE D 288 -58.204 -31.705 -87.237 1.00 49.77 C +ATOM 11259 O ILE D 288 -58.347 -32.741 -86.578 1.00 55.82 O +ATOM 11260 CB ILE D 288 -59.960 -29.903 -87.128 1.00 42.20 C +ATOM 11261 CG1 ILE D 288 -60.235 -28.480 -86.666 1.00 48.70 C +ATOM 11262 CG2 ILE D 288 -61.019 -30.844 -86.606 1.00 47.83 C +ATOM 11263 CD1 ILE D 288 -61.443 -27.879 -87.319 1.00 54.05 C +ATOM 11264 N ALA D 289 -57.750 -31.727 -88.491 1.00 48.21 N +ATOM 11265 CA ALA D 289 -57.385 -32.998 -89.106 1.00 48.78 C +ATOM 11266 C ALA D 289 -56.199 -33.642 -88.398 1.00 51.38 C +ATOM 11267 O ALA D 289 -56.148 -34.872 -88.269 1.00 51.31 O +ATOM 11268 CB ALA D 289 -57.076 -32.797 -90.588 1.00 44.70 C +ATOM 11269 N ALA D 290 -55.253 -32.830 -87.913 1.00 46.95 N +ATOM 11270 CA ALA D 290 -54.072 -33.368 -87.243 1.00 43.29 C +ATOM 11271 C ALA D 290 -54.450 -34.134 -85.986 1.00 47.63 C +ATOM 11272 O ALA D 290 -53.819 -35.144 -85.653 1.00 50.86 O +ATOM 11273 CB ALA D 290 -53.100 -32.242 -86.901 1.00 44.70 C +ATOM 11274 N PHE D 291 -55.467 -33.661 -85.267 1.00 48.86 N +ATOM 11275 CA PHE D 291 -55.879 -34.330 -84.039 1.00 47.47 C +ATOM 11276 C PHE D 291 -56.419 -35.722 -84.331 1.00 52.69 C +ATOM 11277 O PHE D 291 -56.051 -36.693 -83.660 1.00 61.16 O +ATOM 11278 CB PHE D 291 -56.919 -33.487 -83.311 1.00 46.65 C +ATOM 11279 CG PHE D 291 -57.601 -34.206 -82.199 1.00 48.52 C +ATOM 11280 CD1 PHE D 291 -56.908 -34.549 -81.054 1.00 55.85 C +ATOM 11281 CD2 PHE D 291 -58.942 -34.531 -82.291 1.00 56.33 C +ATOM 11282 CE1 PHE D 291 -57.535 -35.214 -80.022 1.00 62.62 C +ATOM 11283 CE2 PHE D 291 -59.579 -35.193 -81.263 1.00 61.54 C +ATOM 11284 CZ PHE D 291 -58.874 -35.535 -80.124 1.00 66.95 C +ATOM 11285 N HIS D 292 -57.287 -35.841 -85.337 1.00 51.22 N +ATOM 11286 CA HIS D 292 -57.829 -37.150 -85.684 1.00 54.04 C +ATOM 11287 C HIS D 292 -56.762 -38.054 -86.289 1.00 53.47 C +ATOM 11288 O HIS D 292 -56.734 -39.257 -86.009 1.00 53.27 O +ATOM 11289 CB HIS D 292 -59.011 -36.989 -86.638 1.00 60.98 C +ATOM 11290 CG HIS D 292 -60.221 -36.384 -85.997 1.00 68.03 C +ATOM 11291 ND1 HIS D 292 -60.415 -35.023 -85.903 1.00 65.10 N +ATOM 11292 CD2 HIS D 292 -61.294 -36.959 -85.404 1.00 72.30 C +ATOM 11293 CE1 HIS D 292 -61.560 -34.785 -85.289 1.00 66.59 C +ATOM 11294 NE2 HIS D 292 -62.113 -35.943 -84.975 1.00 76.88 N +ATOM 11295 N LEU D 293 -55.873 -37.491 -87.115 1.00 52.01 N +ATOM 11296 CA LEU D 293 -54.768 -38.264 -87.682 1.00 50.59 C +ATOM 11297 C LEU D 293 -53.887 -38.852 -86.587 1.00 48.66 C +ATOM 11298 O LEU D 293 -53.508 -40.027 -86.639 1.00 49.48 O +ATOM 11299 CB LEU D 293 -53.944 -37.376 -88.616 1.00 46.68 C +ATOM 11300 CG LEU D 293 -53.017 -37.986 -89.676 1.00 42.85 C +ATOM 11301 CD1 LEU D 293 -51.842 -38.753 -89.094 1.00 45.60 C +ATOM 11302 CD2 LEU D 293 -53.810 -38.875 -90.599 1.00 46.03 C +ATOM 11303 N ASP D 294 -53.510 -38.026 -85.613 1.00 47.77 N +ATOM 11304 CA ASP D 294 -52.701 -38.503 -84.500 1.00 49.21 C +ATOM 11305 C ASP D 294 -53.469 -39.510 -83.651 1.00 49.71 C +ATOM 11306 O ASP D 294 -52.893 -40.479 -83.143 1.00 51.79 O +ATOM 11307 CB ASP D 294 -52.238 -37.307 -83.670 1.00 54.60 C +ATOM 11308 CG ASP D 294 -51.601 -37.709 -82.364 1.00 58.09 C +ATOM 11309 OD1 ASP D 294 -52.349 -38.060 -81.426 1.00 59.66 O +ATOM 11310 OD2 ASP D 294 -50.354 -37.678 -82.282 1.00 57.83 O +ATOM 11311 N ARG D 295 -54.771 -39.288 -83.481 1.00 48.82 N +ATOM 11312 CA ARG D 295 -55.596 -40.230 -82.734 1.00 53.24 C +ATOM 11313 C ARG D 295 -55.672 -41.578 -83.442 1.00 53.64 C +ATOM 11314 O ARG D 295 -55.612 -42.632 -82.797 1.00 52.45 O +ATOM 11315 CB ARG D 295 -56.988 -39.632 -82.540 1.00 53.85 C +ATOM 11316 CG ARG D 295 -58.050 -40.609 -82.111 1.00 54.51 C +ATOM 11317 CD ARG D 295 -59.423 -40.021 -82.337 1.00 57.34 C +ATOM 11318 NE ARG D 295 -59.926 -39.356 -81.141 1.00 67.39 N +ATOM 11319 CZ ARG D 295 -60.969 -38.532 -81.129 1.00 76.54 C +ATOM 11320 NH1 ARG D 295 -61.618 -38.261 -82.254 1.00 69.68 N +ATOM 11321 NH2 ARG D 295 -61.365 -37.979 -79.990 1.00 73.51 N +ATOM 11322 N ILE D 296 -55.785 -41.560 -84.771 1.00 54.75 N +ATOM 11323 CA ILE D 296 -55.921 -42.796 -85.537 1.00 53.19 C +ATOM 11324 C ILE D 296 -54.639 -43.617 -85.458 1.00 52.10 C +ATOM 11325 O ILE D 296 -54.679 -44.851 -85.412 1.00 58.16 O +ATOM 11326 CB ILE D 296 -56.307 -42.479 -86.994 1.00 50.89 C +ATOM 11327 CG1 ILE D 296 -57.824 -42.573 -87.194 1.00 53.67 C +ATOM 11328 CG2 ILE D 296 -55.575 -43.403 -87.971 1.00 48.97 C +ATOM 11329 CD1 ILE D 296 -58.635 -41.658 -86.287 1.00 54.14 C +ATOM 11330 N LEU D 297 -53.483 -42.953 -85.428 1.00 47.32 N +ATOM 11331 CA LEU D 297 -52.219 -43.659 -85.269 1.00 42.43 C +ATOM 11332 C LEU D 297 -51.930 -44.029 -83.826 1.00 51.34 C +ATOM 11333 O LEU D 297 -50.846 -44.553 -83.544 1.00 51.81 O +ATOM 11334 CB LEU D 297 -51.063 -42.825 -85.816 1.00 42.79 C +ATOM 11335 CG LEU D 297 -51.215 -42.374 -87.261 1.00 43.12 C +ATOM 11336 CD1 LEU D 297 -50.007 -41.561 -87.678 1.00 40.94 C +ATOM 11337 CD2 LEU D 297 -51.393 -43.583 -88.156 1.00 44.75 C +ATOM 11338 N ASP D 298 -52.862 -43.754 -82.912 1.00 60.10 N +ATOM 11339 CA ASP D 298 -52.713 -44.095 -81.500 1.00 62.43 C +ATOM 11340 C ASP D 298 -51.448 -43.495 -80.900 1.00 59.91 C +ATOM 11341 O ASP D 298 -50.822 -44.084 -80.013 1.00 57.97 O +ATOM 11342 CB ASP D 298 -52.735 -45.608 -81.285 1.00 62.45 C +ATOM 11343 CG ASP D 298 -53.311 -45.979 -79.952 1.00 64.26 C +ATOM 11344 OD1 ASP D 298 -54.535 -45.812 -79.771 1.00 60.95 O +ATOM 11345 OD2 ASP D 298 -52.527 -46.388 -79.073 1.00 65.24 O +ATOM 11346 N PHE D 299 -51.055 -42.329 -81.406 1.00 52.95 N +ATOM 11347 CA PHE D 299 -49.932 -41.596 -80.843 1.00 53.74 C +ATOM 11348 C PHE D 299 -50.361 -40.808 -79.615 1.00 59.77 C +ATOM 11349 O PHE D 299 -49.679 -40.831 -78.583 1.00 57.84 O +ATOM 11350 CB PHE D 299 -49.341 -40.670 -81.899 1.00 53.42 C +ATOM 11351 CG PHE D 299 -48.438 -41.360 -82.859 1.00 53.80 C +ATOM 11352 CD1 PHE D 299 -47.733 -42.483 -82.470 1.00 53.78 C +ATOM 11353 CD2 PHE D 299 -48.298 -40.894 -84.153 1.00 49.93 C +ATOM 11354 CE1 PHE D 299 -46.897 -43.123 -83.348 1.00 54.61 C +ATOM 11355 CE2 PHE D 299 -47.463 -41.531 -85.039 1.00 49.14 C +ATOM 11356 CZ PHE D 299 -46.761 -42.650 -84.637 1.00 53.73 C +ATOM 11357 N ARG D 300 -51.479 -40.084 -79.733 1.00 61.35 N +ATOM 11358 CA ARG D 300 -52.068 -39.293 -78.652 1.00 57.07 C +ATOM 11359 C ARG D 300 -51.052 -38.284 -78.109 1.00 54.03 C +ATOM 11360 O ARG D 300 -50.750 -38.233 -76.916 1.00 54.73 O +ATOM 11361 CB ARG D 300 -52.626 -40.206 -77.552 1.00 63.13 C +ATOM 11362 CG ARG D 300 -53.850 -41.029 -77.979 1.00 53.16 C +ATOM 11363 CD ARG D 300 -54.009 -42.302 -77.139 1.00 60.18 C +ATOM 11364 NE ARG D 300 -52.766 -43.072 -77.038 1.00 70.77 N +ATOM 11365 CZ ARG D 300 -52.546 -44.049 -76.158 1.00 66.85 C +ATOM 11366 NH1 ARG D 300 -53.485 -44.380 -75.284 1.00 65.39 N +ATOM 11367 NH2 ARG D 300 -51.380 -44.689 -76.140 1.00 59.50 N +ATOM 11368 N ARG D 301 -50.524 -37.478 -79.033 1.00 56.00 N +ATOM 11369 CA ARG D 301 -49.548 -36.440 -78.735 1.00 56.21 C +ATOM 11370 C ARG D 301 -50.054 -35.045 -79.079 1.00 56.23 C +ATOM 11371 O ARG D 301 -49.283 -34.082 -78.981 1.00 54.28 O +ATOM 11372 CB ARG D 301 -48.241 -36.694 -79.503 1.00 51.40 C +ATOM 11373 CG ARG D 301 -47.968 -38.151 -79.837 1.00 51.08 C +ATOM 11374 CD ARG D 301 -47.231 -38.876 -78.733 1.00 56.75 C +ATOM 11375 NE ARG D 301 -46.964 -40.267 -79.090 1.00 59.15 N +ATOM 11376 CZ ARG D 301 -45.960 -40.659 -79.869 1.00 61.51 C +ATOM 11377 NH1 ARG D 301 -45.124 -39.764 -80.382 1.00 57.60 N +ATOM 11378 NH2 ARG D 301 -45.793 -41.947 -80.138 1.00 60.49 N +ATOM 11379 N VAL D 302 -51.300 -34.915 -79.526 1.00 54.02 N +ATOM 11380 CA VAL D 302 -51.856 -33.628 -79.937 1.00 49.41 C +ATOM 11381 C VAL D 302 -52.931 -33.206 -78.944 1.00 52.00 C +ATOM 11382 O VAL D 302 -53.686 -34.056 -78.450 1.00 56.95 O +ATOM 11383 CB VAL D 302 -52.436 -33.696 -81.358 1.00 48.37 C +ATOM 11384 CG1 VAL D 302 -51.332 -33.912 -82.365 1.00 51.60 C +ATOM 11385 CG2 VAL D 302 -53.468 -34.809 -81.454 1.00 45.94 C +ATOM 11386 N PRO D 303 -53.052 -31.919 -78.637 1.00 49.28 N +ATOM 11387 CA PRO D 303 -54.168 -31.459 -77.821 1.00 44.79 C +ATOM 11388 C PRO D 303 -55.455 -31.502 -78.621 1.00 44.38 C +ATOM 11389 O PRO D 303 -55.461 -31.185 -79.821 1.00 47.21 O +ATOM 11390 CB PRO D 303 -53.773 -30.020 -77.463 1.00 45.66 C +ATOM 11391 CG PRO D 303 -52.916 -29.589 -78.589 1.00 48.41 C +ATOM 11392 CD PRO D 303 -52.158 -30.815 -79.025 1.00 50.37 C +ATOM 11393 N PRO D 304 -56.560 -31.897 -77.997 1.00 40.59 N +ATOM 11394 CA PRO D 304 -57.831 -31.973 -78.725 1.00 46.13 C +ATOM 11395 C PRO D 304 -58.241 -30.622 -79.294 1.00 48.99 C +ATOM 11396 O PRO D 304 -58.139 -29.588 -78.632 1.00 51.07 O +ATOM 11397 CB PRO D 304 -58.819 -32.456 -77.657 1.00 45.50 C +ATOM 11398 CG PRO D 304 -57.962 -33.149 -76.644 1.00 50.48 C +ATOM 11399 CD PRO D 304 -56.675 -32.387 -76.617 1.00 42.22 C +ATOM 11400 N VAL D 305 -58.721 -30.643 -80.534 1.00 49.31 N +ATOM 11401 CA VAL D 305 -59.158 -29.438 -81.228 1.00 49.30 C +ATOM 11402 C VAL D 305 -60.452 -29.755 -81.963 1.00 46.58 C +ATOM 11403 O VAL D 305 -60.604 -30.835 -82.542 1.00 46.34 O +ATOM 11404 CB VAL D 305 -58.066 -28.908 -82.185 1.00 49.44 C +ATOM 11405 CG1 VAL D 305 -57.536 -30.017 -83.045 1.00 51.09 C +ATOM 11406 CG2 VAL D 305 -58.602 -27.780 -83.061 1.00 46.54 C +ATOM 11407 N ALA D 306 -61.396 -28.815 -81.916 1.00 48.91 N +ATOM 11408 CA ALA D 306 -62.696 -28.958 -82.556 1.00 57.64 C +ATOM 11409 C ALA D 306 -63.041 -27.673 -83.293 1.00 54.23 C +ATOM 11410 O ALA D 306 -62.692 -26.575 -82.854 1.00 56.26 O +ATOM 11411 CB ALA D 306 -63.794 -29.281 -81.535 1.00 58.96 C +ATOM 11412 N GLY D 307 -63.754 -27.817 -84.405 1.00 48.52 N +ATOM 11413 CA GLY D 307 -64.094 -26.679 -85.236 1.00 54.15 C +ATOM 11414 C GLY D 307 -65.464 -26.123 -84.900 1.00 59.16 C +ATOM 11415 O GLY D 307 -66.381 -26.857 -84.543 1.00 60.42 O +ATOM 11416 N ARG D 308 -65.607 -24.801 -85.027 1.00 56.15 N +ATOM 11417 CA ARG D 308 -66.826 -24.132 -84.598 1.00 56.85 C +ATOM 11418 C ARG D 308 -67.175 -22.990 -85.544 1.00 49.60 C +ATOM 11419 O ARG D 308 -66.291 -22.274 -86.019 1.00 48.63 O +ATOM 11420 CB ARG D 308 -66.672 -23.620 -83.159 1.00 58.09 C +ATOM 11421 CG ARG D 308 -67.875 -22.891 -82.614 1.00 58.42 C +ATOM 11422 CD ARG D 308 -67.634 -22.508 -81.176 1.00 54.99 C +ATOM 11423 NE ARG D 308 -68.729 -21.717 -80.637 1.00 53.81 N +ATOM 11424 CZ ARG D 308 -68.945 -21.554 -79.340 1.00 55.39 C +ATOM 11425 NH1 ARG D 308 -68.148 -22.142 -78.459 1.00 50.69 N +ATOM 11426 NH2 ARG D 308 -69.965 -20.819 -78.924 1.00 64.71 N +ATOM 11427 N LEU D 309 -68.467 -22.856 -85.847 1.00 48.67 N +ATOM 11428 CA LEU D 309 -68.983 -21.716 -86.604 1.00 49.68 C +ATOM 11429 C LEU D 309 -69.239 -20.587 -85.618 1.00 56.38 C +ATOM 11430 O LEU D 309 -70.288 -20.539 -84.972 1.00 54.55 O +ATOM 11431 CB LEU D 309 -70.261 -22.088 -87.346 1.00 51.85 C +ATOM 11432 CG LEU D 309 -70.146 -23.174 -88.416 1.00 61.43 C +ATOM 11433 CD1 LEU D 309 -71.512 -23.603 -88.915 1.00 60.29 C +ATOM 11434 CD2 LEU D 309 -69.295 -22.681 -89.574 1.00 63.60 C +ATOM 11435 N VAL D 310 -68.289 -19.666 -85.498 1.00 59.82 N +ATOM 11436 CA VAL D 310 -68.375 -18.599 -84.508 1.00 63.12 C +ATOM 11437 C VAL D 310 -68.937 -17.345 -85.163 1.00 66.53 C +ATOM 11438 O VAL D 310 -68.755 -17.102 -86.363 1.00 66.14 O +ATOM 11439 CB VAL D 310 -67.009 -18.317 -83.842 1.00 59.59 C +ATOM 11440 CG1 VAL D 310 -66.423 -19.593 -83.249 1.00 56.84 C +ATOM 11441 CG2 VAL D 310 -66.042 -17.701 -84.838 1.00 57.42 C +ATOM 11442 N ASN D 311 -69.652 -16.553 -84.362 1.00 66.46 N +ATOM 11443 CA ASN D 311 -70.198 -15.267 -84.783 1.00 60.17 C +ATOM 11444 C ASN D 311 -69.168 -14.190 -84.462 1.00 59.81 C +ATOM 11445 O ASN D 311 -68.815 -13.998 -83.294 1.00 62.24 O +ATOM 11446 CB ASN D 311 -71.529 -14.999 -84.072 1.00 62.00 C +ATOM 11447 CG ASN D 311 -72.226 -13.726 -84.549 1.00 60.02 C +ATOM 11448 OD1 ASN D 311 -71.583 -12.725 -84.855 1.00 61.36 O +ATOM 11449 ND2 ASN D 311 -73.557 -13.761 -84.592 1.00 55.33 N +ATOM 11450 N MET D 312 -68.681 -13.497 -85.493 1.00 59.24 N +ATOM 11451 CA MET D 312 -67.652 -12.479 -85.292 1.00 59.93 C +ATOM 11452 C MET D 312 -68.187 -11.195 -84.677 1.00 57.41 C +ATOM 11453 O MET D 312 -67.392 -10.298 -84.376 1.00 52.01 O +ATOM 11454 CB MET D 312 -66.943 -12.185 -86.617 1.00 64.25 C +ATOM 11455 CG MET D 312 -67.842 -12.229 -87.839 1.00 63.84 C +ATOM 11456 SD MET D 312 -67.099 -11.502 -89.316 1.00 79.14 S +ATOM 11457 CE MET D 312 -65.410 -12.082 -89.174 1.00 54.45 C +ATOM 11458 N THR D 313 -69.499 -11.085 -84.472 1.00 60.71 N +ATOM 11459 CA THR D 313 -70.074 -9.921 -83.807 1.00 58.09 C +ATOM 11460 C THR D 313 -70.172 -10.131 -82.299 1.00 64.00 C +ATOM 11461 O THR D 313 -69.585 -9.370 -81.523 1.00 66.01 O +ATOM 11462 CB THR D 313 -71.454 -9.600 -84.389 1.00 58.72 C +ATOM 11463 OG1 THR D 313 -71.315 -9.130 -85.736 1.00 52.52 O +ATOM 11464 CG2 THR D 313 -72.145 -8.541 -83.549 1.00 66.21 C +ATOM 11465 N ARG D 314 -70.902 -11.163 -81.870 1.00 66.13 N +ATOM 11466 CA ARG D 314 -71.140 -11.374 -80.448 1.00 72.25 C +ATOM 11467 C ARG D 314 -70.106 -12.275 -79.792 1.00 67.18 C +ATOM 11468 O ARG D 314 -69.967 -12.243 -78.564 1.00 68.81 O +ATOM 11469 CB ARG D 314 -72.533 -11.974 -80.218 1.00 68.80 C +ATOM 11470 CG ARG D 314 -72.704 -13.385 -80.743 1.00 61.78 C +ATOM 11471 CD ARG D 314 -74.076 -13.925 -80.390 1.00 62.39 C +ATOM 11472 NE ARG D 314 -74.235 -15.312 -80.814 1.00 73.12 N +ATOM 11473 CZ ARG D 314 -73.881 -16.361 -80.080 1.00 71.66 C +ATOM 11474 NH1 ARG D 314 -74.058 -17.589 -80.548 1.00 74.47 N +ATOM 11475 NH2 ARG D 314 -73.355 -16.184 -78.877 1.00 69.34 N +ATOM 11476 N GLU D 315 -69.370 -13.064 -80.570 1.00 59.01 N +ATOM 11477 CA GLU D 315 -68.371 -13.952 -80.005 1.00 58.51 C +ATOM 11478 C GLU D 315 -66.944 -13.471 -80.230 1.00 55.80 C +ATOM 11479 O GLU D 315 -66.019 -14.075 -79.682 1.00 61.57 O +ATOM 11480 CB GLU D 315 -68.534 -15.377 -80.569 1.00 64.42 C +ATOM 11481 CG GLU D 315 -69.890 -16.031 -80.268 1.00 69.56 C +ATOM 11482 CD GLU D 315 -69.917 -17.529 -80.579 1.00 75.07 C +ATOM 11483 OE1 GLU D 315 -69.487 -18.325 -79.716 1.00 69.45 O +ATOM 11484 OE2 GLU D 315 -70.374 -17.914 -81.681 1.00 71.01 O +ATOM 11485 N ILE D 316 -66.733 -12.399 -80.995 1.00 55.51 N +ATOM 11486 CA ILE D 316 -65.379 -11.899 -81.222 1.00 60.83 C +ATOM 11487 C ILE D 316 -65.286 -10.424 -80.851 1.00 65.17 C +ATOM 11488 O ILE D 316 -64.606 -10.061 -79.884 1.00 66.61 O +ATOM 11489 CB ILE D 316 -64.923 -12.115 -82.679 1.00 58.35 C +ATOM 11490 CG1 ILE D 316 -64.991 -13.594 -83.073 1.00 64.48 C +ATOM 11491 CG2 ILE D 316 -63.499 -11.613 -82.866 1.00 47.45 C +ATOM 11492 CD1 ILE D 316 -63.925 -14.456 -82.423 1.00 63.71 C +ATOM 11493 N ARG D 317 -65.975 -9.565 -81.610 1.00 63.25 N +ATOM 11494 CA ARG D 317 -65.763 -8.122 -81.496 1.00 58.89 C +ATOM 11495 C ARG D 317 -66.293 -7.572 -80.177 1.00 61.60 C +ATOM 11496 O ARG D 317 -65.596 -6.827 -79.477 1.00 59.09 O +ATOM 11497 CB ARG D 317 -66.420 -7.403 -82.673 1.00 50.31 C +ATOM 11498 CG ARG D 317 -66.242 -5.900 -82.646 1.00 46.30 C +ATOM 11499 CD ARG D 317 -67.073 -5.227 -83.722 1.00 48.36 C +ATOM 11500 NE ARG D 317 -68.502 -5.419 -83.510 1.00 53.12 N +ATOM 11501 CZ ARG D 317 -69.441 -5.055 -84.376 1.00 51.61 C +ATOM 11502 NH1 ARG D 317 -69.107 -4.480 -85.524 1.00 47.65 N +ATOM 11503 NH2 ARG D 317 -70.718 -5.271 -84.095 1.00 54.14 N +ATOM 11504 N ASP D 318 -67.523 -7.923 -79.825 1.00 62.47 N +ATOM 11505 CA ASP D 318 -68.205 -7.335 -78.682 1.00 62.25 C +ATOM 11506 C ASP D 318 -67.828 -7.989 -77.355 1.00 65.20 C +ATOM 11507 O ASP D 318 -68.459 -7.689 -76.335 1.00 66.23 O +ATOM 11508 CB ASP D 318 -69.718 -7.404 -78.900 1.00 60.50 C +ATOM 11509 CG ASP D 318 -70.154 -6.691 -80.170 1.00 58.96 C +ATOM 11510 OD1 ASP D 318 -69.280 -6.158 -80.885 1.00 60.51 O +ATOM 11511 OD2 ASP D 318 -71.367 -6.676 -80.464 1.00 60.88 O +ATOM 11512 N VAL D 319 -66.835 -8.880 -77.341 1.00 60.75 N +ATOM 11513 CA VAL D 319 -66.432 -9.545 -76.105 1.00 59.60 C +ATOM 11514 C VAL D 319 -64.917 -9.540 -75.963 1.00 55.91 C +ATOM 11515 O VAL D 319 -64.327 -10.522 -75.499 1.00 57.94 O +ATOM 11516 CB VAL D 319 -66.972 -10.985 -76.037 1.00 59.66 C +ATOM 11517 CG1 VAL D 319 -68.482 -10.974 -75.838 1.00 63.28 C +ATOM 11518 CG2 VAL D 319 -66.591 -11.760 -77.284 1.00 62.21 C +ATOM 11519 N THR D 320 -64.275 -8.441 -76.348 1.00 51.62 N +ATOM 11520 CA THR D 320 -62.836 -8.307 -76.176 1.00 57.12 C +ATOM 11521 C THR D 320 -62.493 -6.906 -75.702 1.00 63.27 C +ATOM 11522 O THR D 320 -62.946 -5.920 -76.292 1.00 68.20 O +ATOM 11523 CB THR D 320 -62.089 -8.614 -77.476 1.00 55.16 C +ATOM 11524 OG1 THR D 320 -60.709 -8.255 -77.327 1.00 57.33 O +ATOM 11525 CG2 THR D 320 -62.691 -7.850 -78.637 1.00 55.38 C +ATOM 11526 N ARG D 321 -61.702 -6.819 -74.630 1.00 61.99 N +ATOM 11527 CA ARG D 321 -61.151 -5.547 -74.183 1.00 69.21 C +ATOM 11528 C ARG D 321 -59.737 -5.312 -74.709 1.00 72.85 C +ATOM 11529 O ARG D 321 -58.981 -4.533 -74.116 1.00 74.88 O +ATOM 11530 CB ARG D 321 -61.164 -5.441 -72.655 1.00 79.56 C +ATOM 11531 CG ARG D 321 -60.723 -6.685 -71.897 1.00 94.20 C +ATOM 11532 CD ARG D 321 -60.511 -6.371 -70.412 1.00 85.77 C +ATOM 11533 NE ARG D 321 -61.750 -6.022 -69.721 1.00 95.80 N +ATOM 11534 CZ ARG D 321 -62.508 -6.891 -69.061 1.00100.23 C +ATOM 11535 NH1 ARG D 321 -62.157 -8.169 -69.000 1.00 88.96 N +ATOM 11536 NH2 ARG D 321 -63.618 -6.482 -68.459 1.00100.85 N +ATOM 11537 N ASP D 322 -59.355 -5.992 -75.788 1.00 71.15 N +ATOM 11538 CA ASP D 322 -58.046 -5.804 -76.406 1.00 73.95 C +ATOM 11539 C ASP D 322 -58.161 -4.633 -77.381 1.00 71.69 C +ATOM 11540 O ASP D 322 -58.869 -4.724 -78.393 1.00 60.94 O +ATOM 11541 CB ASP D 322 -57.590 -7.085 -77.105 1.00 68.49 C +ATOM 11542 CG ASP D 322 -56.144 -7.015 -77.593 1.00 63.60 C +ATOM 11543 OD1 ASP D 322 -55.846 -6.186 -78.480 1.00 66.24 O +ATOM 11544 OD2 ASP D 322 -55.308 -7.813 -77.112 1.00 55.06 O +ATOM 11545 N LYS D 323 -57.480 -3.526 -77.065 1.00 69.64 N +ATOM 11546 CA LYS D 323 -57.586 -2.336 -77.903 1.00 66.12 C +ATOM 11547 C LYS D 323 -57.007 -2.570 -79.291 1.00 62.52 C +ATOM 11548 O LYS D 323 -57.501 -2.002 -80.270 1.00 64.50 O +ATOM 11549 CB LYS D 323 -56.890 -1.145 -77.239 1.00 69.50 C +ATOM 11550 CG LYS D 323 -57.387 -0.800 -75.836 1.00 79.53 C +ATOM 11551 CD LYS D 323 -56.631 0.404 -75.271 1.00 83.72 C +ATOM 11552 CE LYS D 323 -56.869 1.652 -76.134 1.00 79.33 C +ATOM 11553 NZ LYS D 323 -56.154 2.873 -75.660 1.00 61.85 N +ATOM 11554 N LYS D 324 -55.985 -3.417 -79.401 1.00 63.66 N +ATOM 11555 CA LYS D 324 -55.370 -3.665 -80.700 1.00 61.00 C +ATOM 11556 C LYS D 324 -56.318 -4.425 -81.618 1.00 56.01 C +ATOM 11557 O LYS D 324 -56.534 -4.030 -82.770 1.00 52.86 O +ATOM 11558 CB LYS D 324 -54.063 -4.438 -80.517 1.00 72.31 C +ATOM 11559 CG LYS D 324 -53.314 -4.104 -79.232 1.00 80.44 C +ATOM 11560 CD LYS D 324 -52.218 -5.124 -78.938 1.00 83.70 C +ATOM 11561 CE LYS D 324 -51.239 -5.242 -80.109 1.00 91.56 C +ATOM 11562 NZ LYS D 324 -50.657 -3.938 -80.551 1.00 73.22 N +ATOM 11563 N LEU D 325 -56.898 -5.518 -81.116 1.00 60.20 N +ATOM 11564 CA LEU D 325 -57.730 -6.388 -81.941 1.00 53.28 C +ATOM 11565 C LEU D 325 -59.016 -5.691 -82.368 1.00 50.28 C +ATOM 11566 O LEU D 325 -59.492 -5.891 -83.492 1.00 44.00 O +ATOM 11567 CB LEU D 325 -58.025 -7.684 -81.178 1.00 48.42 C +ATOM 11568 CG LEU D 325 -58.735 -8.875 -81.831 1.00 40.84 C +ATOM 11569 CD1 LEU D 325 -60.234 -8.799 -81.651 1.00 55.06 C +ATOM 11570 CD2 LEU D 325 -58.400 -8.986 -83.303 1.00 51.03 C +ATOM 11571 N TRP D 326 -59.605 -4.882 -81.486 1.00 52.42 N +ATOM 11572 CA TRP D 326 -60.900 -4.294 -81.808 1.00 54.35 C +ATOM 11573 C TRP D 326 -60.786 -3.213 -82.879 1.00 51.81 C +ATOM 11574 O TRP D 326 -61.688 -3.078 -83.714 1.00 49.85 O +ATOM 11575 CB TRP D 326 -61.552 -3.718 -80.552 1.00 56.34 C +ATOM 11576 CG TRP D 326 -62.943 -3.222 -80.807 1.00 61.85 C +ATOM 11577 CD1 TRP D 326 -64.104 -3.935 -80.690 1.00 63.37 C +ATOM 11578 CD2 TRP D 326 -63.318 -1.919 -81.274 1.00 59.81 C +ATOM 11579 NE1 TRP D 326 -65.180 -3.146 -81.028 1.00 61.53 N +ATOM 11580 CE2 TRP D 326 -64.723 -1.906 -81.394 1.00 63.02 C +ATOM 11581 CE3 TRP D 326 -62.601 -0.761 -81.593 1.00 50.48 C +ATOM 11582 CZ2 TRP D 326 -65.425 -0.781 -81.820 1.00 60.66 C +ATOM 11583 CZ3 TRP D 326 -63.296 0.351 -82.015 1.00 55.18 C +ATOM 11584 CH2 TRP D 326 -64.694 0.335 -82.126 1.00 59.92 C +ATOM 11585 N ARG D 327 -59.690 -2.451 -82.893 1.00 46.52 N +ATOM 11586 CA ARG D 327 -59.576 -1.334 -83.827 1.00 40.84 C +ATOM 11587 C ARG D 327 -59.438 -1.767 -85.274 1.00 44.64 C +ATOM 11588 O ARG D 327 -59.284 -0.895 -86.134 1.00 51.46 O +ATOM 11589 CB ARG D 327 -58.387 -0.442 -83.465 1.00 47.38 C +ATOM 11590 CG ARG D 327 -58.621 0.449 -82.260 1.00 64.25 C +ATOM 11591 CD ARG D 327 -58.174 1.884 -82.516 1.00 68.34 C +ATOM 11592 NE ARG D 327 -57.720 2.529 -81.287 1.00 83.25 N +ATOM 11593 CZ ARG D 327 -56.458 2.535 -80.866 1.00 90.51 C +ATOM 11594 NH1 ARG D 327 -55.516 1.935 -81.585 1.00 80.28 N +ATOM 11595 NH2 ARG D 327 -56.137 3.143 -79.729 1.00 94.55 N +ATOM 11596 N THR D 328 -59.478 -3.062 -85.579 1.00 45.10 N +ATOM 11597 CA THR D 328 -59.374 -3.527 -86.955 1.00 41.87 C +ATOM 11598 C THR D 328 -60.682 -4.088 -87.484 1.00 41.92 C +ATOM 11599 O THR D 328 -60.689 -4.711 -88.549 1.00 46.90 O +ATOM 11600 CB THR D 328 -58.288 -4.591 -87.090 1.00 39.88 C +ATOM 11601 OG1 THR D 328 -58.741 -5.806 -86.488 1.00 40.80 O +ATOM 11602 CG2 THR D 328 -57.012 -4.137 -86.401 1.00 45.26 C +ATOM 11603 N PHE D 329 -61.783 -3.912 -86.763 1.00 44.41 N +ATOM 11604 CA PHE D 329 -63.073 -4.443 -87.196 1.00 49.95 C +ATOM 11605 C PHE D 329 -63.760 -3.424 -88.096 1.00 52.32 C +ATOM 11606 O PHE D 329 -64.379 -2.472 -87.619 1.00 62.00 O +ATOM 11607 CB PHE D 329 -63.937 -4.804 -85.995 1.00 51.04 C +ATOM 11608 CG PHE D 329 -63.963 -6.273 -85.697 1.00 44.20 C +ATOM 11609 CD1 PHE D 329 -63.004 -6.843 -84.878 1.00 41.17 C +ATOM 11610 CD2 PHE D 329 -64.949 -7.082 -86.235 1.00 39.23 C +ATOM 11611 CE1 PHE D 329 -63.028 -8.192 -84.604 1.00 42.69 C +ATOM 11612 CE2 PHE D 329 -64.980 -8.429 -85.965 1.00 41.52 C +ATOM 11613 CZ PHE D 329 -64.017 -8.987 -85.150 1.00 45.41 C +ATOM 11614 N PHE D 330 -63.638 -3.623 -89.405 1.00 46.09 N +ATOM 11615 CA PHE D 330 -64.269 -2.780 -90.407 1.00 48.57 C +ATOM 11616 C PHE D 330 -65.291 -3.579 -91.206 1.00 52.99 C +ATOM 11617 O PHE D 330 -65.271 -4.812 -91.227 1.00 52.58 O +ATOM 11618 CB PHE D 330 -63.232 -2.194 -91.366 1.00 54.55 C +ATOM 11619 CG PHE D 330 -62.561 -3.228 -92.233 1.00 63.69 C +ATOM 11620 CD1 PHE D 330 -61.453 -3.926 -91.773 1.00 58.08 C +ATOM 11621 CD2 PHE D 330 -63.052 -3.517 -93.501 1.00 60.27 C +ATOM 11622 CE1 PHE D 330 -60.840 -4.882 -92.567 1.00 53.60 C +ATOM 11623 CE2 PHE D 330 -62.447 -4.473 -94.295 1.00 54.95 C +ATOM 11624 CZ PHE D 330 -61.338 -5.152 -93.830 1.00 53.59 C +ATOM 11625 N VAL D 331 -66.168 -2.859 -91.899 1.00 55.23 N +ATOM 11626 CA VAL D 331 -67.155 -3.461 -92.787 1.00 54.00 C +ATOM 11627 C VAL D 331 -66.722 -3.200 -94.224 1.00 61.18 C +ATOM 11628 O VAL D 331 -66.375 -2.066 -94.580 1.00 61.99 O +ATOM 11629 CB VAL D 331 -68.567 -2.916 -92.521 1.00 54.60 C +ATOM 11630 CG1 VAL D 331 -69.600 -3.726 -93.298 1.00 51.10 C +ATOM 11631 CG2 VAL D 331 -68.862 -2.926 -91.033 1.00 57.18 C +ATOM 11632 N SER D 332 -66.743 -4.245 -95.040 1.00 60.55 N +ATOM 11633 CA SER D 332 -66.188 -4.229 -96.386 1.00 52.55 C +ATOM 11634 C SER D 332 -67.205 -3.697 -97.381 1.00 52.51 C +ATOM 11635 O SER D 332 -68.391 -3.570 -97.074 1.00 57.00 O +ATOM 11636 CB SER D 332 -65.772 -5.639 -96.778 1.00 51.25 C +ATOM 11637 OG SER D 332 -66.918 -6.420 -97.061 1.00 52.32 O +ATOM 11638 N PRO D 333 -66.768 -3.380 -98.606 1.00 55.12 N +ATOM 11639 CA PRO D 333 -67.726 -2.958 -99.643 1.00 55.28 C +ATOM 11640 C PRO D 333 -68.798 -3.986 -99.948 1.00 49.16 C +ATOM 11641 O PRO D 333 -69.853 -3.617-100.481 1.00 49.80 O +ATOM 11642 CB PRO D 333 -66.831 -2.709-100.863 1.00 54.80 C +ATOM 11643 CG PRO D 333 -65.525 -2.334-100.282 1.00 56.58 C +ATOM 11644 CD PRO D 333 -65.375 -3.169 -99.040 1.00 55.45 C +ATOM 11645 N ALA D 334 -68.563 -5.261 -99.663 1.00 48.04 N +ATOM 11646 CA ALA D 334 -69.618 -6.254 -99.794 1.00 58.22 C +ATOM 11647 C ALA D 334 -70.542 -6.289 -98.586 1.00 63.00 C +ATOM 11648 O ALA D 334 -71.311 -7.246 -98.443 1.00 70.37 O +ATOM 11649 CB ALA D 334 -69.017 -7.643-100.021 1.00 60.85 C +ATOM 11650 N ASN D 335 -70.482 -5.270 -97.724 1.00 64.28 N +ATOM 11651 CA ASN D 335 -71.310 -5.180 -96.520 1.00 70.23 C +ATOM 11652 C ASN D 335 -71.089 -6.375 -95.592 1.00 69.30 C +ATOM 11653 O ASN D 335 -71.979 -6.767 -94.832 1.00 68.62 O +ATOM 11654 CB ASN D 335 -72.792 -5.027 -96.874 1.00 72.66 C +ATOM 11655 CG ASN D 335 -73.558 -4.240 -95.831 1.00 76.37 C +ATOM 11656 OD1 ASN D 335 -73.595 -3.011 -95.874 1.00 68.78 O +ATOM 11657 ND2 ASN D 335 -74.181 -4.945 -94.890 1.00 86.53 N +ATOM 11658 N ASN D 336 -69.902 -6.970 -95.660 1.00 63.87 N +ATOM 11659 CA ASN D 336 -69.488 -8.047 -94.775 1.00 57.28 C +ATOM 11660 C ASN D 336 -68.575 -7.511 -93.679 1.00 63.07 C +ATOM 11661 O ASN D 336 -67.890 -6.498 -93.851 1.00 60.47 O +ATOM 11662 CB ASN D 336 -68.772 -9.143 -95.558 1.00 51.78 C +ATOM 11663 CG ASN D 336 -69.630 -9.715 -96.650 1.00 54.01 C +ATOM 11664 OD1 ASN D 336 -70.855 -9.644 -96.579 1.00 56.30 O +ATOM 11665 ND2 ASN D 336 -69.000 -10.279 -97.675 1.00 53.33 N +ATOM 11666 N ILE D 337 -68.583 -8.192 -92.538 1.00 64.48 N +ATOM 11667 CA ILE D 337 -67.750 -7.802 -91.408 1.00 58.01 C +ATOM 11668 C ILE D 337 -66.397 -8.483 -91.533 1.00 50.77 C +ATOM 11669 O ILE D 337 -66.308 -9.682 -91.820 1.00 47.78 O +ATOM 11670 CB ILE D 337 -68.438 -8.143 -90.075 1.00 49.08 C +ATOM 11671 CG1 ILE D 337 -69.870 -7.605 -90.082 1.00 49.81 C +ATOM 11672 CG2 ILE D 337 -67.655 -7.557 -88.914 1.00 51.03 C +ATOM 11673 CD1 ILE D 337 -70.630 -7.841 -88.797 1.00 61.24 C +ATOM 11674 N CYS D 338 -65.336 -7.711 -91.305 1.00 48.69 N +ATOM 11675 CA CYS D 338 -63.977 -8.189 -91.482 1.00 48.82 C +ATOM 11676 C CYS D 338 -63.119 -7.748 -90.303 1.00 48.58 C +ATOM 11677 O CYS D 338 -63.411 -6.756 -89.632 1.00 50.63 O +ATOM 11678 CB CYS D 338 -63.371 -7.656 -92.787 1.00 53.44 C +ATOM 11679 SG CYS D 338 -64.344 -7.954 -94.278 1.00 52.41 S +ATOM 11680 N PHE D 339 -62.046 -8.499 -90.063 1.00 45.25 N +ATOM 11681 CA PHE D 339 -61.027 -8.116 -89.094 1.00 44.07 C +ATOM 11682 C PHE D 339 -59.732 -8.816 -89.467 1.00 42.74 C +ATOM 11683 O PHE D 339 -59.749 -9.878 -90.092 1.00 44.39 O +ATOM 11684 CB PHE D 339 -61.429 -8.461 -87.655 1.00 47.15 C +ATOM 11685 CG PHE D 339 -61.269 -9.917 -87.305 1.00 44.08 C +ATOM 11686 CD1 PHE D 339 -62.217 -10.847 -87.699 1.00 38.18 C +ATOM 11687 CD2 PHE D 339 -60.169 -10.353 -86.580 1.00 42.34 C +ATOM 11688 CE1 PHE D 339 -62.075 -12.177 -87.377 1.00 38.00 C +ATOM 11689 CE2 PHE D 339 -60.020 -11.687 -86.258 1.00 38.00 C +ATOM 11690 CZ PHE D 339 -60.975 -12.600 -86.659 1.00 38.00 C +ATOM 11691 N TYR D 340 -58.608 -8.201 -89.104 1.00 41.01 N +ATOM 11692 CA TYR D 340 -57.322 -8.796 -89.447 1.00 43.10 C +ATOM 11693 C TYR D 340 -56.402 -8.910 -88.241 1.00 40.50 C +ATOM 11694 O TYR D 340 -55.544 -9.800 -88.196 1.00 47.91 O +ATOM 11695 CB TYR D 340 -56.643 -8.013 -90.580 1.00 47.65 C +ATOM 11696 CG TYR D 340 -56.622 -6.500 -90.448 1.00 49.42 C +ATOM 11697 CD1 TYR D 340 -57.722 -5.732 -90.821 1.00 48.49 C +ATOM 11698 CD2 TYR D 340 -55.486 -5.837 -89.998 1.00 50.37 C +ATOM 11699 CE1 TYR D 340 -57.700 -4.350 -90.721 1.00 45.64 C +ATOM 11700 CE2 TYR D 340 -55.454 -4.456 -89.896 1.00 47.73 C +ATOM 11701 CZ TYR D 340 -56.563 -3.719 -90.259 1.00 49.53 C +ATOM 11702 OH TYR D 340 -56.539 -2.347 -90.162 1.00 56.75 O +ATOM 11703 N GLY D 341 -56.566 -8.035 -87.262 1.00 41.36 N +ATOM 11704 CA GLY D 341 -55.726 -8.096 -86.086 1.00 51.09 C +ATOM 11705 C GLY D 341 -54.411 -7.358 -86.254 1.00 51.32 C +ATOM 11706 O GLY D 341 -54.260 -6.444 -87.070 1.00 52.46 O +ATOM 11707 N GLU D 342 -53.442 -7.764 -85.444 1.00 51.03 N +ATOM 11708 CA GLU D 342 -52.143 -7.119 -85.457 1.00 61.35 C +ATOM 11709 C GLU D 342 -51.066 -8.139 -85.105 1.00 58.49 C +ATOM 11710 O GLU D 342 -50.374 -8.034 -84.097 1.00 60.83 O +ATOM 11711 CB GLU D 342 -52.110 -5.927 -84.503 1.00 71.20 C +ATOM 11712 CG GLU D 342 -51.508 -4.675 -85.111 1.00 75.53 C +ATOM 11713 CD GLU D 342 -51.708 -3.452 -84.239 1.00 95.00 C +ATOM 11714 OE1 GLU D 342 -51.800 -3.614 -83.003 1.00 89.44 O +ATOM 11715 OE2 GLU D 342 -51.760 -2.330 -84.787 1.00115.45 O +ATOM 11716 N CYS D 343 -50.934 -9.174 -85.930 1.00 56.45 N +ATOM 11717 CA CYS D 343 -49.808 -10.085 -85.781 1.00 55.82 C +ATOM 11718 C CYS D 343 -48.658 -9.622 -86.666 1.00 57.31 C +ATOM 11719 O CYS D 343 -48.285 -8.446 -86.631 1.00 67.91 O +ATOM 11720 CB CYS D 343 -50.219 -11.515 -86.114 1.00 58.22 C +ATOM 11721 SG CYS D 343 -50.542 -11.801 -87.858 1.00 72.47 S +ATOM 11722 N SER D 344 -48.108 -10.515 -87.488 1.00 50.50 N +ATOM 11723 CA SER D 344 -46.947 -10.144 -88.291 1.00 50.56 C +ATOM 11724 C SER D 344 -47.045 -10.681 -89.716 1.00 53.44 C +ATOM 11725 O SER D 344 -46.543 -10.051 -90.653 1.00 49.46 O +ATOM 11726 CB SER D 344 -45.657 -10.616 -87.610 1.00 53.46 C +ATOM 11727 OG SER D 344 -45.554 -12.027 -87.606 1.00 64.85 O +ATOM 11728 N TYR D 345 -47.642 -11.859 -89.882 1.00 57.40 N +ATOM 11729 CA TYR D 345 -47.862 -12.482 -91.185 1.00 48.97 C +ATOM 11730 C TYR D 345 -49.339 -12.405 -91.538 1.00 46.30 C +ATOM 11731 O TYR D 345 -50.178 -12.925 -90.798 1.00 55.00 O +ATOM 11732 CB TYR D 345 -47.410 -13.942 -91.190 1.00 57.51 C +ATOM 11733 CG TYR D 345 -46.039 -14.165 -91.774 1.00 61.51 C +ATOM 11734 CD1 TYR D 345 -45.158 -13.108 -91.945 1.00 61.18 C +ATOM 11735 CD2 TYR D 345 -45.630 -15.431 -92.166 1.00 61.18 C +ATOM 11736 CE1 TYR D 345 -43.905 -13.306 -92.477 1.00 58.05 C +ATOM 11737 CE2 TYR D 345 -44.378 -15.637 -92.703 1.00 62.76 C +ATOM 11738 CZ TYR D 345 -43.518 -14.568 -92.857 1.00 60.59 C +ATOM 11739 OH TYR D 345 -42.263 -14.748 -93.390 1.00 64.27 O +ATOM 11740 N TYR D 346 -49.656 -11.748 -92.651 1.00 46.25 N +ATOM 11741 CA TYR D 346 -51.026 -11.710 -93.168 1.00 50.31 C +ATOM 11742 C TYR D 346 -51.984 -11.125 -92.132 1.00 51.61 C +ATOM 11743 O TYR D 346 -53.082 -11.640 -91.908 1.00 46.22 O +ATOM 11744 CB TYR D 346 -51.497 -13.096 -93.628 1.00 48.55 C +ATOM 11745 CG TYR D 346 -50.474 -13.848 -94.454 1.00 52.70 C +ATOM 11746 CD1 TYR D 346 -49.798 -13.228 -95.497 1.00 54.69 C +ATOM 11747 CD2 TYR D 346 -50.185 -15.182 -94.192 1.00 54.93 C +ATOM 11748 CE1 TYR D 346 -48.855 -13.913 -96.249 1.00 57.37 C +ATOM 11749 CE2 TYR D 346 -49.247 -15.875 -94.940 1.00 54.04 C +ATOM 11750 CZ TYR D 346 -48.586 -15.236 -95.966 1.00 56.71 C +ATOM 11751 OH TYR D 346 -47.653 -15.923 -96.710 1.00 58.23 O +ATOM 11752 N CYS D 347 -51.530 -10.083 -91.448 1.00 52.63 N +ATOM 11753 CA CYS D 347 -52.357 -9.296 -90.539 1.00 53.13 C +ATOM 11754 C CYS D 347 -52.432 -7.877 -91.094 1.00 53.60 C +ATOM 11755 O CYS D 347 -51.835 -6.945 -90.547 1.00 59.48 O +ATOM 11756 CB CYS D 347 -51.806 -9.330 -89.107 1.00 56.88 C +ATOM 11757 SG CYS D 347 -52.287 -10.824 -88.219 1.00 57.97 S +ATOM 11758 N SER D 348 -53.151 -7.727 -92.205 1.00 52.55 N +ATOM 11759 CA SER D 348 -53.366 -6.432 -92.835 1.00 56.98 C +ATOM 11760 C SER D 348 -54.726 -6.448 -93.524 1.00 49.77 C +ATOM 11761 O SER D 348 -55.401 -7.481 -93.586 1.00 47.50 O +ATOM 11762 CB SER D 348 -52.232 -6.098 -93.817 1.00 60.75 C +ATOM 11763 OG SER D 348 -51.945 -7.183 -94.686 1.00 52.38 O +ATOM 11764 N THR D 349 -55.122 -5.285 -94.050 1.00 44.34 N +ATOM 11765 CA THR D 349 -56.434 -5.159 -94.680 1.00 41.66 C +ATOM 11766 C THR D 349 -56.587 -6.138 -95.833 1.00 42.95 C +ATOM 11767 O THR D 349 -57.667 -6.702 -96.044 1.00 38.00 O +ATOM 11768 CB THR D 349 -56.647 -3.732 -95.181 1.00 45.74 C +ATOM 11769 OG1 THR D 349 -56.362 -2.799 -94.132 1.00 54.38 O +ATOM 11770 CG2 THR D 349 -58.084 -3.545 -95.645 1.00 42.96 C +ATOM 11771 N GLU D 350 -55.516 -6.344 -96.596 1.00 50.08 N +ATOM 11772 CA GLU D 350 -55.559 -7.183 -97.783 1.00 45.83 C +ATOM 11773 C GLU D 350 -55.544 -8.671 -97.457 1.00 46.11 C +ATOM 11774 O GLU D 350 -55.560 -9.493 -98.379 1.00 50.06 O +ATOM 11775 CB GLU D 350 -54.401 -6.826 -98.724 1.00 39.84 C +ATOM 11776 CG GLU D 350 -53.165 -6.231 -98.045 1.00 44.98 C +ATOM 11777 CD GLU D 350 -53.218 -4.713 -97.882 1.00 45.06 C +ATOM 11778 OE1 GLU D 350 -54.033 -4.221 -97.079 1.00 48.21 O +ATOM 11779 OE2 GLU D 350 -52.433 -4.009 -98.550 1.00 43.80 O +ATOM 11780 N HIS D 351 -55.520 -9.042 -96.177 1.00 39.22 N +ATOM 11781 CA HIS D 351 -55.744 -10.427 -95.782 1.00 45.63 C +ATOM 11782 C HIS D 351 -56.867 -10.527 -94.763 1.00 44.88 C +ATOM 11783 O HIS D 351 -56.937 -11.510 -94.016 1.00 45.55 O +ATOM 11784 CB HIS D 351 -54.473 -11.064 -95.220 1.00 52.55 C +ATOM 11785 CG HIS D 351 -53.505 -11.514 -96.268 1.00 51.68 C +ATOM 11786 ND1 HIS D 351 -52.415 -10.762 -96.646 1.00 51.20 N +ATOM 11787 CD2 HIS D 351 -53.457 -12.646 -97.008 1.00 47.22 C +ATOM 11788 CE1 HIS D 351 -51.740 -11.407 -97.581 1.00 48.58 C +ATOM 11789 NE2 HIS D 351 -52.352 -12.553 -97.818 1.00 47.76 N +ATOM 11790 N ALA D 352 -57.754 -9.536 -94.736 1.00 43.99 N +ATOM 11791 CA ALA D 352 -58.794 -9.485 -93.721 1.00 47.77 C +ATOM 11792 C ALA D 352 -59.685 -10.713 -93.795 1.00 46.35 C +ATOM 11793 O ALA D 352 -60.032 -11.188 -94.879 1.00 48.36 O +ATOM 11794 CB ALA D 352 -59.636 -8.221 -93.883 1.00 53.56 C +ATOM 11795 N LEU D 353 -60.044 -11.227 -92.625 1.00 43.97 N +ATOM 11796 CA LEU D 353 -60.942 -12.366 -92.515 1.00 49.34 C +ATOM 11797 C LEU D 353 -62.376 -11.861 -92.417 1.00 48.60 C +ATOM 11798 O LEU D 353 -62.721 -11.138 -91.475 1.00 45.37 O +ATOM 11799 CB LEU D 353 -60.569 -13.208 -91.298 1.00 52.06 C +ATOM 11800 CG LEU D 353 -59.105 -13.656 -91.303 1.00 52.09 C +ATOM 11801 CD1 LEU D 353 -58.746 -14.384 -90.015 1.00 45.28 C +ATOM 11802 CD2 LEU D 353 -58.824 -14.518 -92.528 1.00 61.68 C +ATOM 11803 N CYS D 354 -63.212 -12.254 -93.376 1.00 47.95 N +ATOM 11804 CA CYS D 354 -64.588 -11.788 -93.460 1.00 50.81 C +ATOM 11805 C CYS D 354 -65.546 -12.969 -93.484 1.00 49.09 C +ATOM 11806 O CYS D 354 -65.230 -14.026 -94.037 1.00 51.10 O +ATOM 11807 CB CYS D 354 -64.819 -10.929 -94.710 1.00 50.27 C +ATOM 11808 SG CYS D 354 -63.565 -9.674 -95.032 1.00 55.50 S +ATOM 11809 N GLY D 355 -66.705 -12.789 -92.852 1.00 45.94 N +ATOM 11810 CA GLY D 355 -67.812 -13.704 -92.996 1.00 47.67 C +ATOM 11811 C GLY D 355 -68.812 -13.204 -94.027 1.00 58.26 C +ATOM 11812 O GLY D 355 -68.660 -12.142 -94.624 1.00 64.58 O +ATOM 11813 N LYS D 356 -69.862 -13.998 -94.225 1.00 62.15 N +ATOM 11814 CA LYS D 356 -70.950 -13.639 -95.133 1.00 60.55 C +ATOM 11815 C LYS D 356 -72.272 -13.809 -94.399 1.00 57.48 C +ATOM 11816 O LYS D 356 -72.894 -14.878 -94.445 1.00 57.50 O +ATOM 11817 CB LYS D 356 -70.911 -14.467 -96.416 1.00 64.75 C +ATOM 11818 CG LYS D 356 -71.893 -13.993 -97.490 1.00 70.19 C +ATOM 11819 CD LYS D 356 -71.775 -12.493 -97.736 1.00 69.22 C +ATOM 11820 CE LYS D 356 -72.677 -12.033 -98.877 1.00 65.43 C +ATOM 11821 NZ LYS D 356 -71.907 -11.339 -99.955 1.00 59.03 N +ATOM 11822 N PRO D 357 -72.735 -12.765 -93.702 1.00 59.07 N +ATOM 11823 CA PRO D 357 -71.959 -11.527 -93.561 1.00 59.88 C +ATOM 11824 C PRO D 357 -71.171 -11.401 -92.250 1.00 56.79 C +ATOM 11825 O PRO D 357 -70.368 -10.475 -92.122 1.00 49.31 O +ATOM 11826 CB PRO D 357 -73.040 -10.450 -93.646 1.00 62.27 C +ATOM 11827 CG PRO D 357 -74.247 -11.100 -93.024 1.00 63.22 C +ATOM 11828 CD PRO D 357 -74.150 -12.580 -93.331 1.00 57.97 C +ATOM 11829 N ASP D 358 -71.370 -12.327 -91.306 1.00 61.84 N +ATOM 11830 CA ASP D 358 -70.778 -12.174 -89.980 1.00 60.96 C +ATOM 11831 C ASP D 358 -70.551 -13.529 -89.312 1.00 62.57 C +ATOM 11832 O ASP D 358 -70.709 -13.669 -88.095 1.00 61.87 O +ATOM 11833 CB ASP D 358 -71.646 -11.280 -89.090 1.00 57.29 C +ATOM 11834 CG ASP D 358 -73.047 -11.833 -88.892 1.00 57.56 C +ATOM 11835 OD1 ASP D 358 -73.559 -12.517 -89.803 1.00 58.43 O +ATOM 11836 OD2 ASP D 358 -73.648 -11.559 -87.832 1.00 65.99 O +ATOM 11837 N GLN D 359 -70.114 -14.522 -90.079 1.00 61.50 N +ATOM 11838 CA GLN D 359 -69.742 -15.812 -89.519 1.00 60.68 C +ATOM 11839 C GLN D 359 -68.446 -16.251 -90.168 1.00 62.87 C +ATOM 11840 O GLN D 359 -68.334 -16.237 -91.397 1.00 73.46 O +ATOM 11841 CB GLN D 359 -70.829 -16.863 -89.740 1.00 58.40 C +ATOM 11842 CG GLN D 359 -72.117 -16.548 -89.030 1.00 52.30 C +ATOM 11843 CD GLN D 359 -72.963 -17.776 -88.825 1.00 50.61 C +ATOM 11844 OE1 GLN D 359 -72.731 -18.561 -87.904 1.00 57.97 O +ATOM 11845 NE2 GLN D 359 -73.972 -17.939 -89.669 1.00 51.05 N +ATOM 11846 N ILE D 360 -67.469 -16.642 -89.356 1.00 56.28 N +ATOM 11847 CA ILE D 360 -66.102 -16.707 -89.831 1.00 59.40 C +ATOM 11848 C ILE D 360 -65.534 -18.130 -89.863 1.00 59.88 C +ATOM 11849 O ILE D 360 -64.777 -18.450 -90.791 1.00 61.73 O +ATOM 11850 CB ILE D 360 -65.202 -15.773 -88.990 1.00 56.07 C +ATOM 11851 CG1 ILE D 360 -63.842 -16.407 -88.687 1.00 60.13 C +ATOM 11852 CG2 ILE D 360 -65.921 -15.374 -87.710 1.00 60.21 C +ATOM 11853 CD1 ILE D 360 -62.916 -15.528 -87.861 1.00 57.86 C +ATOM 11854 N GLU D 361 -65.916 -19.011 -88.927 1.00 52.17 N +ATOM 11855 CA GLU D 361 -65.437 -20.400 -88.871 1.00 47.54 C +ATOM 11856 C GLU D 361 -63.973 -20.490 -88.420 1.00 46.84 C +ATOM 11857 O GLU D 361 -63.170 -19.600 -88.716 1.00 51.94 O +ATOM 11858 CB GLU D 361 -65.637 -21.082 -90.237 1.00 52.48 C +ATOM 11859 CG GLU D 361 -65.049 -22.485 -90.393 1.00 56.80 C +ATOM 11860 CD GLU D 361 -65.251 -23.091 -91.792 1.00 58.44 C +ATOM 11861 OE1 GLU D 361 -64.321 -23.760 -92.300 1.00 53.27 O +ATOM 11862 OE2 GLU D 361 -66.354 -22.935 -92.368 1.00 59.18 O +ATOM 11863 N GLY D 362 -63.619 -21.550 -87.700 1.00 49.99 N +ATOM 11864 CA GLY D 362 -62.264 -21.710 -87.205 1.00 43.63 C +ATOM 11865 C GLY D 362 -62.151 -22.916 -86.296 1.00 44.05 C +ATOM 11866 O GLY D 362 -63.112 -23.664 -86.091 1.00 45.87 O +ATOM 11867 N SER D 363 -60.947 -23.096 -85.750 1.00 41.55 N +ATOM 11868 CA SER D 363 -60.650 -24.228 -84.882 1.00 43.71 C +ATOM 11869 C SER D 363 -60.301 -23.772 -83.469 1.00 46.04 C +ATOM 11870 O SER D 363 -59.632 -22.754 -83.271 1.00 42.13 O +ATOM 11871 CB SER D 363 -59.480 -25.038 -85.409 1.00 45.57 C +ATOM 11872 OG SER D 363 -58.293 -24.276 -85.295 1.00 45.62 O +ATOM 11873 N LEU D 364 -60.697 -24.582 -82.488 1.00 48.28 N +ATOM 11874 CA LEU D 364 -60.453 -24.311 -81.071 1.00 46.66 C +ATOM 11875 C LEU D 364 -59.541 -25.402 -80.522 1.00 53.73 C +ATOM 11876 O LEU D 364 -60.011 -26.488 -80.168 1.00 55.58 O +ATOM 11877 CB LEU D 364 -61.761 -24.273 -80.287 1.00 46.45 C +ATOM 11878 CG LEU D 364 -62.585 -22.991 -80.253 1.00 46.97 C +ATOM 11879 CD1 LEU D 364 -61.696 -21.846 -79.815 1.00 49.15 C +ATOM 11880 CD2 LEU D 364 -63.252 -22.711 -81.592 1.00 48.71 C +ATOM 11881 N ALA D 365 -58.247 -25.116 -80.413 1.00 56.29 N +ATOM 11882 CA ALA D 365 -57.301 -26.067 -79.843 1.00 50.37 C +ATOM 11883 C ALA D 365 -57.292 -25.898 -78.331 1.00 48.47 C +ATOM 11884 O ALA D 365 -57.017 -24.802 -77.832 1.00 54.30 O +ATOM 11885 CB ALA D 365 -55.899 -25.861 -80.418 1.00 54.97 C +ATOM 11886 N ALA D 366 -57.593 -26.975 -77.608 1.00 51.32 N +ATOM 11887 CA ALA D 366 -57.636 -26.913 -76.152 1.00 50.92 C +ATOM 11888 C ALA D 366 -56.297 -26.450 -75.593 1.00 49.07 C +ATOM 11889 O ALA D 366 -55.233 -26.692 -76.171 1.00 48.73 O +ATOM 11890 CB ALA D 366 -58.002 -28.274 -75.560 1.00 49.04 C +ATOM 11891 N PHE D 367 -56.358 -25.759 -74.463 1.00 48.14 N +ATOM 11892 CA PHE D 367 -55.171 -25.148 -73.888 1.00 51.28 C +ATOM 11893 C PHE D 367 -54.447 -26.150 -73.002 1.00 54.62 C +ATOM 11894 O PHE D 367 -55.047 -26.733 -72.092 1.00 54.21 O +ATOM 11895 CB PHE D 367 -55.538 -23.897 -73.091 1.00 50.04 C +ATOM 11896 CG PHE D 367 -54.764 -22.675 -73.497 1.00 54.27 C +ATOM 11897 CD1 PHE D 367 -53.448 -22.782 -73.919 1.00 61.34 C +ATOM 11898 CD2 PHE D 367 -55.353 -21.422 -73.471 1.00 51.53 C +ATOM 11899 CE1 PHE D 367 -52.732 -21.661 -74.297 1.00 62.32 C +ATOM 11900 CE2 PHE D 367 -54.645 -20.299 -73.849 1.00 50.81 C +ATOM 11901 CZ PHE D 367 -53.333 -20.418 -74.262 1.00 57.36 C +ATOM 11902 N LEU D 368 -53.157 -26.348 -73.282 1.00 53.29 N +ATOM 11903 CA LEU D 368 -52.302 -27.124 -72.403 1.00 48.77 C +ATOM 11904 C LEU D 368 -52.244 -26.452 -71.034 1.00 53.42 C +ATOM 11905 O LEU D 368 -52.453 -25.242 -70.923 1.00 55.18 O +ATOM 11906 CB LEU D 368 -50.900 -27.231 -72.998 1.00 49.53 C +ATOM 11907 CG LEU D 368 -50.724 -28.198 -74.165 1.00 56.00 C +ATOM 11908 CD1 LEU D 368 -49.265 -28.220 -74.611 1.00 53.13 C +ATOM 11909 CD2 LEU D 368 -51.207 -29.592 -73.780 1.00 56.57 C +ATOM 11910 N PRO D 369 -51.958 -27.210 -69.973 1.00 53.89 N +ATOM 11911 CA PRO D 369 -51.983 -26.615 -68.634 1.00 51.16 C +ATOM 11912 C PRO D 369 -50.938 -25.514 -68.512 1.00 59.11 C +ATOM 11913 O PRO D 369 -49.932 -25.500 -69.228 1.00 56.26 O +ATOM 11914 CB PRO D 369 -51.674 -27.797 -67.712 1.00 49.54 C +ATOM 11915 CG PRO D 369 -50.916 -28.734 -68.559 1.00 52.09 C +ATOM 11916 CD PRO D 369 -51.492 -28.607 -69.934 1.00 56.27 C +ATOM 11917 N ASP D 370 -51.196 -24.590 -67.584 1.00 58.48 N +ATOM 11918 CA ASP D 370 -50.375 -23.394 -67.430 1.00 52.06 C +ATOM 11919 C ASP D 370 -48.907 -23.739 -67.223 1.00 51.06 C +ATOM 11920 O ASP D 370 -48.566 -24.581 -66.390 1.00 53.76 O +ATOM 11921 CB ASP D 370 -50.875 -22.568 -66.246 1.00 50.33 C +ATOM 11922 CG ASP D 370 -50.216 -21.210 -66.174 1.00 60.41 C +ATOM 11923 OD1 ASP D 370 -49.733 -20.739 -67.226 1.00 65.80 O +ATOM 11924 OD2 ASP D 370 -50.159 -20.622 -65.074 1.00 56.21 O +ATOM 11925 N LEU D 371 -48.034 -23.059 -67.972 1.00 47.77 N +ATOM 11926 CA LEU D 371 -46.603 -23.341 -67.922 1.00 49.73 C +ATOM 11927 C LEU D 371 -46.002 -23.147 -66.539 1.00 48.89 C +ATOM 11928 O LEU D 371 -44.820 -23.456 -66.353 1.00 46.60 O +ATOM 11929 CB LEU D 371 -45.845 -22.468 -68.918 1.00 42.24 C +ATOM 11930 CG LEU D 371 -46.046 -22.794 -70.392 1.00 46.56 C +ATOM 11931 CD1 LEU D 371 -47.250 -22.045 -70.945 1.00 52.58 C +ATOM 11932 CD2 LEU D 371 -44.775 -22.483 -71.172 1.00 38.43 C +ATOM 11933 N ALA D 372 -46.759 -22.605 -65.585 1.00 48.43 N +ATOM 11934 CA ALA D 372 -46.228 -22.400 -64.244 1.00 51.92 C +ATOM 11935 C ALA D 372 -46.079 -23.722 -63.494 1.00 56.53 C +ATOM 11936 O ALA D 372 -45.029 -23.993 -62.897 1.00 50.35 O +ATOM 11937 CB ALA D 372 -47.129 -21.435 -63.478 1.00 54.66 C +ATOM 11938 N LEU D 373 -47.116 -24.564 -63.524 1.00 57.57 N +ATOM 11939 CA LEU D 373 -47.109 -25.866 -62.866 1.00 52.95 C +ATOM 11940 C LEU D 373 -46.940 -27.027 -63.839 1.00 54.50 C +ATOM 11941 O LEU D 373 -47.178 -28.180 -63.463 1.00 58.42 O +ATOM 11942 CB LEU D 373 -48.393 -26.057 -62.054 1.00 43.74 C +ATOM 11943 CG LEU D 373 -49.741 -25.597 -62.615 1.00 43.52 C +ATOM 11944 CD1 LEU D 373 -50.089 -26.252 -63.938 1.00 46.84 C +ATOM 11945 CD2 LEU D 373 -50.823 -25.896 -61.599 1.00 55.22 C +ATOM 11946 N ALA D 374 -46.560 -26.748 -65.079 1.00 54.13 N +ATOM 11947 CA ALA D 374 -46.363 -27.767 -66.094 1.00 50.85 C +ATOM 11948 C ALA D 374 -45.370 -27.228 -67.121 1.00 52.50 C +ATOM 11949 O ALA D 374 -45.669 -27.100 -68.311 1.00 48.59 O +ATOM 11950 CB ALA D 374 -47.697 -28.153 -66.729 1.00 49.20 C +ATOM 11951 N LYS D 375 -44.164 -26.906 -66.649 1.00 47.98 N +ATOM 11952 CA LYS D 375 -43.137 -26.354 -67.523 1.00 55.11 C +ATOM 11953 C LYS D 375 -42.882 -27.273 -68.710 1.00 54.65 C +ATOM 11954 O LYS D 375 -42.886 -28.499 -68.580 1.00 61.10 O +ATOM 11955 CB LYS D 375 -41.836 -26.117 -66.746 1.00 63.16 C +ATOM 11956 CG LYS D 375 -41.711 -24.725 -66.102 1.00 73.13 C +ATOM 11957 CD LYS D 375 -42.299 -24.671 -64.691 1.00 74.28 C +ATOM 11958 CE LYS D 375 -42.103 -23.297 -64.043 1.00 67.50 C +ATOM 11959 NZ LYS D 375 -42.719 -22.192 -64.839 1.00 67.62 N +ATOM 11960 N ARG D 376 -42.670 -26.670 -69.879 1.00 51.76 N +ATOM 11961 CA ARG D 376 -42.436 -27.407 -71.113 1.00 48.60 C +ATOM 11962 C ARG D 376 -41.075 -27.031 -71.675 1.00 52.06 C +ATOM 11963 O ARG D 376 -40.833 -25.862 -71.992 1.00 59.88 O +ATOM 11964 CB ARG D 376 -43.528 -27.130 -72.149 1.00 42.05 C +ATOM 11965 CG ARG D 376 -44.925 -27.269 -71.606 1.00 43.10 C +ATOM 11966 CD ARG D 376 -45.919 -27.480 -72.731 1.00 49.47 C +ATOM 11967 NE ARG D 376 -47.094 -26.630 -72.597 1.00 56.86 N +ATOM 11968 CZ ARG D 376 -47.258 -25.486 -73.246 1.00 51.22 C +ATOM 11969 NH1 ARG D 376 -46.316 -25.069 -74.081 1.00 58.55 N +ATOM 11970 NH2 ARG D 376 -48.360 -24.766 -73.064 1.00 44.24 N +ATOM 11971 N LYS D 377 -40.194 -28.017 -71.794 1.00 50.25 N +ATOM 11972 CA LYS D 377 -38.964 -27.817 -72.539 1.00 50.07 C +ATOM 11973 C LYS D 377 -39.298 -27.568 -74.003 1.00 47.71 C +ATOM 11974 O LYS D 377 -40.356 -27.952 -74.502 1.00 49.05 O +ATOM 11975 CB LYS D 377 -38.049 -29.036 -72.414 1.00 56.35 C +ATOM 11976 CG LYS D 377 -36.574 -28.800 -72.764 1.00 53.11 C +ATOM 11977 CD LYS D 377 -35.842 -28.058 -71.654 1.00 59.87 C +ATOM 11978 CE LYS D 377 -34.359 -28.409 -71.641 1.00 47.62 C +ATOM 11979 NZ LYS D 377 -33.689 -28.083 -72.923 1.00 40.04 N +ATOM 11980 N THR D 378 -38.382 -26.913 -74.699 1.00 48.83 N +ATOM 11981 CA THR D 378 -38.562 -26.633 -76.116 1.00 53.24 C +ATOM 11982 C THR D 378 -37.262 -26.979 -76.828 1.00 52.86 C +ATOM 11983 O THR D 378 -36.229 -26.348 -76.585 1.00 56.20 O +ATOM 11984 CB THR D 378 -38.973 -25.175 -76.339 1.00 59.65 C +ATOM 11985 OG1 THR D 378 -38.707 -24.796 -77.693 1.00 62.82 O +ATOM 11986 CG2 THR D 378 -38.233 -24.243 -75.375 1.00 66.50 C +ATOM 11987 N TRP D 379 -37.307 -27.991 -77.688 1.00 49.89 N +ATOM 11988 CA TRP D 379 -36.122 -28.508 -78.352 1.00 47.99 C +ATOM 11989 C TRP D 379 -36.090 -28.062 -79.805 1.00 47.54 C +ATOM 11990 O TRP D 379 -37.130 -27.903 -80.449 1.00 46.13 O +ATOM 11991 CB TRP D 379 -36.072 -30.035 -78.295 1.00 52.65 C +ATOM 11992 CG TRP D 379 -36.203 -30.611 -76.927 1.00 55.00 C +ATOM 11993 CD1 TRP D 379 -37.336 -30.687 -76.178 1.00 55.63 C +ATOM 11994 CD2 TRP D 379 -35.164 -31.216 -76.149 1.00 54.72 C +ATOM 11995 NE1 TRP D 379 -37.068 -31.293 -74.975 1.00 54.86 N +ATOM 11996 CE2 TRP D 379 -35.740 -31.627 -74.933 1.00 51.45 C +ATOM 11997 CE3 TRP D 379 -33.802 -31.446 -76.361 1.00 54.67 C +ATOM 11998 CZ2 TRP D 379 -35.003 -32.252 -73.934 1.00 52.60 C +ATOM 11999 CZ3 TRP D 379 -33.073 -32.068 -75.367 1.00 55.30 C +ATOM 12000 CH2 TRP D 379 -33.673 -32.463 -74.169 1.00 55.25 C +ATOM 12001 N ARG D 380 -34.877 -27.880 -80.316 1.00 47.56 N +ATOM 12002 CA ARG D 380 -34.664 -27.467 -81.696 1.00 51.06 C +ATOM 12003 C ARG D 380 -34.499 -28.716 -82.550 1.00 52.71 C +ATOM 12004 O ARG D 380 -33.645 -29.561 -82.263 1.00 58.77 O +ATOM 12005 CB ARG D 380 -33.439 -26.559 -81.804 1.00 59.76 C +ATOM 12006 CG ARG D 380 -32.993 -26.237 -83.231 1.00 66.36 C +ATOM 12007 CD ARG D 380 -31.650 -25.504 -83.237 1.00 72.56 C +ATOM 12008 NE ARG D 380 -31.543 -24.524 -84.318 1.00 77.98 N +ATOM 12009 CZ ARG D 380 -30.879 -24.737 -85.450 1.00 70.73 C +ATOM 12010 NH1 ARG D 380 -30.268 -25.897 -85.640 1.00 69.23 N +ATOM 12011 NH2 ARG D 380 -30.820 -23.798 -86.387 1.00 64.32 N +ATOM 12012 N ASN D 381 -35.318 -28.833 -83.587 1.00 52.82 N +ATOM 12013 CA ASN D 381 -35.272 -30.007 -84.445 1.00 55.93 C +ATOM 12014 C ASN D 381 -33.920 -30.073 -85.147 1.00 58.28 C +ATOM 12015 O ASN D 381 -33.478 -29.070 -85.724 1.00 62.98 O +ATOM 12016 CB ASN D 381 -36.412 -29.947 -85.465 1.00 59.41 C +ATOM 12017 CG ASN D 381 -36.586 -31.240 -86.246 1.00 56.17 C +ATOM 12018 OD1 ASN D 381 -35.632 -31.982 -86.478 1.00 58.93 O +ATOM 12019 ND2 ASN D 381 -37.820 -31.519 -86.647 1.00 41.74 N +ATOM 12020 N PRO D 382 -33.227 -31.216 -85.112 1.00 50.99 N +ATOM 12021 CA PRO D 382 -31.958 -31.317 -85.848 1.00 52.99 C +ATOM 12022 C PRO D 382 -32.131 -31.294 -87.350 1.00 50.83 C +ATOM 12023 O PRO D 382 -31.148 -31.065 -88.061 1.00 58.07 O +ATOM 12024 CB PRO D 382 -31.380 -32.655 -85.377 1.00 51.35 C +ATOM 12025 CG PRO D 382 -32.554 -33.414 -84.917 1.00 50.10 C +ATOM 12026 CD PRO D 382 -33.491 -32.420 -84.313 1.00 42.63 C +ATOM 12027 N TRP D 383 -33.335 -31.544 -87.860 1.00 53.14 N +ATOM 12028 CA TRP D 383 -33.619 -31.382 -89.278 1.00 59.26 C +ATOM 12029 C TRP D 383 -34.361 -30.082 -89.573 1.00 58.67 C +ATOM 12030 O TRP D 383 -35.022 -29.975 -90.610 1.00 62.05 O +ATOM 12031 CB TRP D 383 -34.396 -32.591 -89.803 1.00 57.61 C +ATOM 12032 CG TRP D 383 -33.569 -33.851 -89.821 1.00 61.93 C +ATOM 12033 CD1 TRP D 383 -32.747 -34.276 -90.824 1.00 59.83 C +ATOM 12034 CD2 TRP D 383 -33.469 -34.833 -88.780 1.00 59.75 C +ATOM 12035 NE1 TRP D 383 -32.150 -35.464 -90.478 1.00 57.86 N +ATOM 12036 CE2 TRP D 383 -32.575 -35.827 -89.228 1.00 56.52 C +ATOM 12037 CE3 TRP D 383 -34.052 -34.971 -87.518 1.00 59.25 C +ATOM 12038 CZ2 TRP D 383 -32.251 -36.941 -88.457 1.00 54.56 C +ATOM 12039 CZ3 TRP D 383 -33.728 -36.078 -86.754 1.00 57.61 C +ATOM 12040 CH2 TRP D 383 -32.836 -37.046 -87.225 1.00 57.75 C +ATOM 12041 N ARG D 384 -34.240 -29.088 -88.690 1.00 57.68 N +ATOM 12042 CA ARG D 384 -34.919 -27.808 -88.864 1.00 61.97 C +ATOM 12043 C ARG D 384 -34.413 -27.086 -90.106 1.00 61.52 C +ATOM 12044 O ARG D 384 -33.207 -26.894 -90.280 1.00 61.44 O +ATOM 12045 CB ARG D 384 -34.704 -26.936 -87.622 1.00 63.42 C +ATOM 12046 CG ARG D 384 -35.163 -25.482 -87.749 1.00 74.95 C +ATOM 12047 CD ARG D 384 -34.561 -24.592 -86.649 1.00 72.74 C +ATOM 12048 NE ARG D 384 -35.279 -23.322 -86.504 1.00 77.26 N +ATOM 12049 CZ ARG D 384 -34.834 -22.142 -86.932 1.00 75.73 C +ATOM 12050 NH1 ARG D 384 -33.655 -22.050 -87.535 1.00 66.74 N +ATOM 12051 NH2 ARG D 384 -35.569 -21.050 -86.753 1.00 69.82 N +ATOM 12052 N ARG D 385 -35.340 -26.695 -90.978 1.00 58.52 N +ATOM 12053 CA ARG D 385 -34.973 -25.958 -92.180 1.00 61.96 C +ATOM 12054 C ARG D 385 -34.333 -24.620 -91.826 1.00 68.09 C +ATOM 12055 O ARG D 385 -34.598 -24.038 -90.772 1.00 73.40 O +ATOM 12056 CB ARG D 385 -36.196 -25.743 -93.065 1.00 64.48 C +ATOM 12057 CG ARG D 385 -36.645 -26.998 -93.782 1.00 57.98 C +ATOM 12058 CD ARG D 385 -38.060 -26.856 -94.272 1.00 54.95 C +ATOM 12059 NE ARG D 385 -38.710 -28.148 -94.429 1.00 49.57 N +ATOM 12060 CZ ARG D 385 -38.535 -28.936 -95.481 1.00 51.58 C +ATOM 12061 NH1 ARG D 385 -37.722 -28.565 -96.458 1.00 51.56 N +ATOM 12062 NH2 ARG D 385 -39.172 -30.094 -95.553 1.00 60.75 N +ATOM 12063 N SER D 386 -33.459 -24.143 -92.719 1.00 66.08 N +ATOM 12064 CA SER D 386 -32.720 -22.907 -92.474 1.00 70.50 C +ATOM 12065 C SER D 386 -33.616 -21.675 -92.408 1.00 73.49 C +ATOM 12066 O SER D 386 -33.177 -20.638 -91.895 1.00 76.02 O +ATOM 12067 CB SER D 386 -31.662 -22.703 -93.559 1.00 74.08 C +ATOM 12068 OG SER D 386 -32.267 -22.527 -94.828 1.00 78.68 O +ATOM 12069 N TYR D 387 -34.841 -21.756 -92.932 1.00 74.97 N +ATOM 12070 CA TYR D 387 -35.784 -20.633 -92.959 1.00 76.21 C +ATOM 12071 C TYR D 387 -35.130 -19.388 -93.551 1.00 81.12 C +ATOM 12072 O TYR D 387 -35.226 -18.283 -93.012 1.00 88.67 O +ATOM 12073 CB TYR D 387 -36.356 -20.347 -91.567 1.00 77.91 C +ATOM 12074 CG TYR D 387 -37.259 -21.444 -91.055 1.00 74.14 C +ATOM 12075 CD1 TYR D 387 -38.308 -21.922 -91.826 1.00 71.41 C +ATOM 12076 CD2 TYR D 387 -37.045 -22.018 -89.812 1.00 74.75 C +ATOM 12077 CE1 TYR D 387 -39.124 -22.938 -91.374 1.00 79.15 C +ATOM 12078 CE2 TYR D 387 -37.854 -23.032 -89.348 1.00 79.64 C +ATOM 12079 CZ TYR D 387 -38.894 -23.490 -90.132 1.00 83.45 C +ATOM 12080 OH TYR D 387 -39.706 -24.503 -89.671 1.00 94.06 O +ATOM 12081 N HIS D 388 -34.476 -19.577 -94.696 1.00 84.41 N +ATOM 12082 CA HIS D 388 -33.761 -18.505 -95.376 1.00 87.63 C +ATOM 12083 C HIS D 388 -33.609 -18.903 -96.835 1.00 85.32 C +ATOM 12084 O HIS D 388 -33.127 -20.000 -97.129 1.00 84.56 O +ATOM 12085 CB HIS D 388 -32.385 -18.258 -94.736 1.00 86.37 C +ATOM 12086 CG HIS D 388 -32.395 -17.236 -93.638 1.00100.87 C +ATOM 12087 ND1 HIS D 388 -33.293 -16.190 -93.602 1.00113.63 N +ATOM 12088 CD2 HIS D 388 -31.631 -17.113 -92.525 1.00 98.15 C +ATOM 12089 CE1 HIS D 388 -33.075 -15.462 -92.521 1.00110.77 C +ATOM 12090 NE2 HIS D 388 -32.072 -16.001 -91.849 1.00 99.91 N +ATOM 12091 N LYS D 389 -34.048 -18.027 -97.738 1.00 87.32 N +ATOM 12092 CA LYS D 389 -33.898 -18.285 -99.164 1.00 85.09 C +ATOM 12093 C LYS D 389 -32.421 -18.390 -99.540 1.00 92.32 C +ATOM 12094 O LYS D 389 -31.544 -17.852 -98.857 1.00 96.40 O +ATOM 12095 CB LYS D 389 -34.583 -17.186 -99.987 1.00 81.39 C +ATOM 12096 CG LYS D 389 -35.097 -15.972 -99.189 1.00 81.78 C +ATOM 12097 CD LYS D 389 -35.596 -14.861-100.126 1.00 68.73 C +ATOM 12098 CE LYS D 389 -36.316 -13.755 -99.373 1.00 55.55 C +ATOM 12099 NZ LYS D 389 -37.610 -14.232 -98.813 1.00 57.60 N +ATOM 12100 N ARG D 390 -32.155 -19.122-100.628 1.00 89.88 N +ATOM 12101 CA ARG D 390 -30.817 -19.331-101.186 1.00 92.90 C +ATOM 12102 C ARG D 390 -29.991 -20.255-100.294 1.00 85.07 C +ATOM 12103 O ARG D 390 -29.478 -21.280-100.746 1.00 81.76 O +ATOM 12104 CB ARG D 390 -30.081 -17.998-101.396 1.00 91.89 C +ATOM 12105 CG ARG D 390 -30.734 -17.055-102.409 1.00 90.96 C +ATOM 12106 CD ARG D 390 -30.951 -15.677-101.780 1.00 91.88 C +ATOM 12107 NE ARG D 390 -31.658 -14.750-102.663 1.00 89.06 N +ATOM 12108 CZ ARG D 390 -32.149 -13.571-102.281 1.00 85.52 C +ATOM 12109 NH1 ARG D 390 -32.020 -13.166-101.023 1.00 75.12 N +ATOM 12110 NH2 ARG D 390 -32.774 -12.795-103.158 1.00 75.71 N +ATOM 12111 N LYS D 391 -29.844 -19.878 -99.032 1.00 87.95 N +ATOM 12112 CA LYS D 391 -28.960 -20.568 -98.104 1.00 84.76 C +ATOM 12113 C LYS D 391 -29.485 -21.965 -97.794 1.00 78.70 C +ATOM 12114 O LYS D 391 -30.647 -22.133 -97.415 1.00 88.22 O +ATOM 12115 CB LYS D 391 -28.836 -19.738 -96.833 1.00 90.12 C +ATOM 12116 CG LYS D 391 -28.738 -18.236 -97.133 1.00 97.47 C +ATOM 12117 CD LYS D 391 -29.156 -17.346 -95.963 1.00 97.58 C +ATOM 12118 CE LYS D 391 -30.093 -16.247 -96.486 1.00 87.44 C +ATOM 12119 NZ LYS D 391 -29.564 -15.528 -97.713 1.00 70.70 N +ATOM 12120 N LYS D 392 -28.635 -22.975 -97.980 1.00 71.53 N +ATOM 12121 CA LYS D 392 -29.042 -24.359 -97.777 1.00 71.09 C +ATOM 12122 C LYS D 392 -29.022 -24.688 -96.285 1.00 59.38 C +ATOM 12123 O LYS D 392 -28.899 -23.809 -95.428 1.00 55.35 O +ATOM 12124 CB LYS D 392 -28.154 -25.295 -98.592 1.00 76.85 C +ATOM 12125 CG LYS D 392 -28.907 -26.112 -99.647 1.00 74.05 C +ATOM 12126 CD LYS D 392 -28.027 -27.203-100.252 1.00 70.60 C +ATOM 12127 CE LYS D 392 -26.957 -26.596-101.146 1.00 83.57 C +ATOM 12128 NZ LYS D 392 -26.147 -27.606-101.880 1.00 83.60 N +ATOM 12129 N ALA D 393 -29.129 -25.977 -95.969 1.00 59.41 N +ATOM 12130 CA ALA D 393 -29.201 -26.459 -94.597 1.00 65.47 C +ATOM 12131 C ALA D 393 -28.288 -27.668 -94.442 1.00 73.90 C +ATOM 12132 O ALA D 393 -27.920 -28.319 -95.421 1.00 84.02 O +ATOM 12133 CB ALA D 393 -30.639 -26.821 -94.203 1.00 66.07 C +ATOM 12134 N GLU D 394 -27.925 -27.962 -93.188 1.00 70.72 N +ATOM 12135 CA GLU D 394 -26.932 -29.002 -92.922 1.00 76.16 C +ATOM 12136 C GLU D 394 -27.408 -30.376 -93.385 1.00 71.99 C +ATOM 12137 O GLU D 394 -26.700 -31.072 -94.123 1.00 70.88 O +ATOM 12138 CB GLU D 394 -26.583 -29.027 -91.432 1.00 82.36 C +ATOM 12139 CG GLU D 394 -25.081 -29.038 -91.150 1.00 85.48 C +ATOM 12140 CD GLU D 394 -24.388 -30.301 -91.640 1.00 83.01 C +ATOM 12141 OE1 GLU D 394 -24.314 -31.279 -90.866 1.00 67.24 O +ATOM 12142 OE2 GLU D 394 -23.920 -30.315 -92.800 1.00 91.52 O +ATOM 12143 N TRP D 395 -28.606 -30.786 -92.960 1.00 69.65 N +ATOM 12144 CA TRP D 395 -29.117 -32.111 -93.302 1.00 66.21 C +ATOM 12145 C TRP D 395 -29.351 -32.292 -94.794 1.00 64.36 C +ATOM 12146 O TRP D 395 -29.597 -33.422 -95.228 1.00 67.99 O +ATOM 12147 CB TRP D 395 -30.413 -32.402 -92.535 1.00 70.03 C +ATOM 12148 CG TRP D 395 -31.495 -31.355 -92.688 1.00 73.37 C +ATOM 12149 CD1 TRP D 395 -31.569 -30.153 -92.045 1.00 71.13 C +ATOM 12150 CD2 TRP D 395 -32.651 -31.425 -93.536 1.00 67.37 C +ATOM 12151 NE1 TRP D 395 -32.697 -29.473 -92.438 1.00 67.29 N +ATOM 12152 CE2 TRP D 395 -33.376 -30.231 -93.354 1.00 66.29 C +ATOM 12153 CE3 TRP D 395 -33.140 -32.378 -94.433 1.00 66.81 C +ATOM 12154 CZ2 TRP D 395 -34.561 -29.966 -94.037 1.00 67.37 C +ATOM 12155 CZ3 TRP D 395 -34.318 -32.112 -95.107 1.00 64.13 C +ATOM 12156 CH2 TRP D 395 -35.014 -30.918 -94.906 1.00 66.92 C +ATOM 12157 N GLU D 396 -29.275 -31.225 -95.583 1.00 61.01 N +ATOM 12158 CA GLU D 396 -29.482 -31.299 -97.021 1.00 66.78 C +ATOM 12159 C GLU D 396 -28.190 -31.503 -97.809 1.00 70.11 C +ATOM 12160 O GLU D 396 -28.212 -31.408 -99.040 1.00 69.63 O +ATOM 12161 CB GLU D 396 -30.200 -30.040 -97.516 1.00 73.64 C +ATOM 12162 CG GLU D 396 -31.626 -29.889 -96.996 1.00 64.93 C +ATOM 12163 CD GLU D 396 -32.334 -28.669 -97.565 1.00 68.41 C +ATOM 12164 OE1 GLU D 396 -31.663 -27.803 -98.168 1.00 68.09 O +ATOM 12165 OE2 GLU D 396 -33.573 -28.595 -97.435 1.00 66.57 O +ATOM 12166 N VAL D 397 -27.069 -31.758 -97.135 1.00 72.52 N +ATOM 12167 CA VAL D 397 -25.805 -31.998 -97.826 1.00 70.59 C +ATOM 12168 C VAL D 397 -25.038 -33.196 -97.286 1.00 73.42 C +ATOM 12169 O VAL D 397 -24.193 -33.758 -98.007 1.00 78.48 O +ATOM 12170 CB VAL D 397 -24.920 -30.734 -97.782 1.00 68.35 C +ATOM 12171 CG1 VAL D 397 -24.295 -30.566 -96.395 1.00 71.63 C +ATOM 12172 CG2 VAL D 397 -23.863 -30.778 -98.881 1.00 57.13 C +ATOM 12173 N ASP D 398 -25.272 -33.631 -96.052 1.00 74.40 N +ATOM 12174 CA ASP D 398 -24.602 -34.793 -95.484 1.00 75.49 C +ATOM 12175 C ASP D 398 -25.587 -35.952 -95.445 1.00 81.11 C +ATOM 12176 O ASP D 398 -26.549 -35.909 -94.661 1.00 84.04 O +ATOM 12177 CB ASP D 398 -24.086 -34.482 -94.077 1.00 76.16 C +ATOM 12178 CG ASP D 398 -23.203 -35.588 -93.516 1.00 84.76 C +ATOM 12179 OD1 ASP D 398 -23.625 -36.765 -93.527 1.00 82.15 O +ATOM 12180 OD2 ASP D 398 -22.092 -35.276 -93.035 1.00 95.64 O +ATOM 12181 N PRO D 399 -25.403 -37.000 -96.253 1.00 82.72 N +ATOM 12182 CA PRO D 399 -26.365 -38.114 -96.244 1.00 81.16 C +ATOM 12183 C PRO D 399 -26.263 -39.001 -95.016 1.00 81.20 C +ATOM 12184 O PRO D 399 -27.194 -39.774 -94.755 1.00 81.53 O +ATOM 12185 CB PRO D 399 -26.009 -38.889 -97.516 1.00 84.37 C +ATOM 12186 CG PRO D 399 -24.544 -38.633 -97.693 1.00 89.07 C +ATOM 12187 CD PRO D 399 -24.284 -37.238 -97.181 1.00 84.36 C +ATOM 12188 N ASP D 400 -25.176 -38.908 -94.252 1.00 77.44 N +ATOM 12189 CA ASP D 400 -25.006 -39.663 -93.018 1.00 78.32 C +ATOM 12190 C ASP D 400 -25.294 -38.811 -91.790 1.00 81.62 C +ATOM 12191 O ASP D 400 -24.807 -39.124 -90.700 1.00 87.09 O +ATOM 12192 CB ASP D 400 -23.593 -40.243 -92.934 1.00 87.34 C +ATOM 12193 CG ASP D 400 -23.252 -41.135 -94.115 1.00 87.65 C +ATOM 12194 OD1 ASP D 400 -24.189 -41.642 -94.763 1.00 97.31 O +ATOM 12195 OD2 ASP D 400 -22.049 -41.331 -94.397 1.00 79.11 O +ATOM 12196 N TYR D 401 -26.045 -37.718 -91.966 1.00 76.54 N +ATOM 12197 CA TYR D 401 -26.363 -36.809 -90.868 1.00 75.83 C +ATOM 12198 C TYR D 401 -26.822 -37.569 -89.628 1.00 79.56 C +ATOM 12199 O TYR D 401 -26.359 -37.296 -88.513 1.00 80.07 O +ATOM 12200 CB TYR D 401 -27.430 -35.805 -91.321 1.00 75.16 C +ATOM 12201 CG TYR D 401 -27.710 -34.670 -90.350 1.00 73.42 C +ATOM 12202 CD1 TYR D 401 -28.431 -34.885 -89.181 1.00 75.31 C +ATOM 12203 CD2 TYR D 401 -27.262 -33.380 -90.609 1.00 73.24 C +ATOM 12204 CE1 TYR D 401 -28.688 -33.859 -88.294 1.00 71.36 C +ATOM 12205 CE2 TYR D 401 -27.520 -32.341 -89.724 1.00 72.74 C +ATOM 12206 CZ TYR D 401 -28.233 -32.591 -88.568 1.00 71.34 C +ATOM 12207 OH TYR D 401 -28.497 -31.580 -87.672 1.00 72.01 O +ATOM 12208 N CYS D 402 -27.722 -38.542 -89.805 1.00 74.24 N +ATOM 12209 CA CYS D 402 -28.288 -39.234 -88.651 1.00 73.59 C +ATOM 12210 C CYS D 402 -27.217 -39.948 -87.835 1.00 83.12 C +ATOM 12211 O CYS D 402 -27.328 -40.027 -86.606 1.00 84.34 O +ATOM 12212 CB CYS D 402 -29.358 -40.225 -89.109 1.00 70.23 C +ATOM 12213 SG CYS D 402 -30.150 -41.118 -87.747 1.00 78.69 S +ATOM 12214 N ASP D 403 -26.150 -40.424 -88.486 1.00 88.00 N +ATOM 12215 CA ASP D 403 -25.074 -41.096 -87.764 1.00 87.23 C +ATOM 12216 C ASP D 403 -24.319 -40.146 -86.852 1.00 90.14 C +ATOM 12217 O ASP D 403 -23.662 -40.600 -85.910 1.00 96.13 O +ATOM 12218 CB ASP D 403 -24.100 -41.748 -88.748 1.00 84.20 C +ATOM 12219 CG ASP D 403 -24.788 -42.715 -89.695 1.00 96.50 C +ATOM 12220 OD1 ASP D 403 -25.895 -43.188 -89.360 1.00 93.01 O +ATOM 12221 OD2 ASP D 403 -24.225 -42.996 -90.778 1.00 93.12 O +ATOM 12222 N GLU D 404 -24.414 -38.840 -87.096 1.00 89.12 N +ATOM 12223 CA GLU D 404 -23.857 -37.855 -86.180 1.00 88.79 C +ATOM 12224 C GLU D 404 -24.880 -37.385 -85.165 1.00 81.50 C +ATOM 12225 O GLU D 404 -24.514 -37.045 -84.034 1.00 83.84 O +ATOM 12226 CB GLU D 404 -23.320 -36.644 -86.948 1.00 97.23 C +ATOM 12227 CG GLU D 404 -22.178 -35.919 -86.242 1.00105.18 C +ATOM 12228 CD GLU D 404 -21.614 -34.773 -87.066 1.00118.48 C +ATOM 12229 OE1 GLU D 404 -22.201 -33.668 -87.037 1.00104.05 O +ATOM 12230 OE2 GLU D 404 -20.586 -34.978 -87.747 1.00137.60 O +ATOM 12231 N VAL D 405 -26.162 -37.378 -85.535 1.00 75.09 N +ATOM 12232 CA VAL D 405 -27.181 -36.898 -84.609 1.00 75.75 C +ATOM 12233 C VAL D 405 -27.587 -37.965 -83.611 1.00 77.46 C +ATOM 12234 O VAL D 405 -28.205 -37.638 -82.593 1.00 79.95 O +ATOM 12235 CB VAL D 405 -28.420 -36.389 -85.370 1.00 69.57 C +ATOM 12236 CG1 VAL D 405 -29.381 -37.525 -85.666 1.00 71.62 C +ATOM 12237 CG2 VAL D 405 -29.111 -35.286 -84.590 1.00 67.84 C +ATOM 12238 N LYS D 406 -27.220 -39.223 -83.844 1.00 80.97 N +ATOM 12239 CA LYS D 406 -27.424 -40.265 -82.851 1.00 82.14 C +ATOM 12240 C LYS D 406 -26.248 -40.366 -81.887 1.00 80.57 C +ATOM 12241 O LYS D 406 -26.166 -41.327 -81.114 1.00 75.20 O +ATOM 12242 CB LYS D 406 -27.694 -41.609 -83.536 1.00 77.27 C +ATOM 12243 CG LYS D 406 -26.536 -42.163 -84.333 1.00 85.48 C +ATOM 12244 CD LYS D 406 -26.897 -43.530 -84.904 1.00 97.79 C +ATOM 12245 CE LYS D 406 -28.118 -43.444 -85.819 1.00 91.18 C +ATOM 12246 NZ LYS D 406 -28.915 -44.709 -85.875 1.00 79.13 N +ATOM 12247 N GLN D 407 -25.355 -39.377 -81.907 1.00 81.73 N +ATOM 12248 CA GLN D 407 -24.262 -39.263 -80.956 1.00 82.18 C +ATOM 12249 C GLN D 407 -24.466 -38.127 -79.964 1.00 82.94 C +ATOM 12250 O GLN D 407 -23.711 -38.036 -78.989 1.00 85.65 O +ATOM 12251 CB GLN D 407 -22.931 -39.046 -81.693 1.00 82.84 C +ATOM 12252 CG GLN D 407 -21.773 -39.837 -81.125 1.00 82.30 C +ATOM 12253 CD GLN D 407 -21.424 -41.028 -81.992 1.00 83.23 C +ATOM 12254 OE1 GLN D 407 -21.557 -40.972 -83.212 1.00 73.28 O +ATOM 12255 NE2 GLN D 407 -20.982 -42.117 -81.365 1.00 85.78 N +ATOM 12256 N THR D 408 -25.446 -37.251 -80.202 1.00 76.92 N +ATOM 12257 CA THR D 408 -25.748 -36.154 -79.296 1.00 78.81 C +ATOM 12258 C THR D 408 -26.245 -36.687 -77.952 1.00 77.29 C +ATOM 12259 O THR D 408 -26.779 -37.797 -77.874 1.00 82.94 O +ATOM 12260 CB THR D 408 -26.796 -35.242 -79.922 1.00 78.35 C +ATOM 12261 OG1 THR D 408 -27.522 -35.979 -80.912 1.00 79.56 O +ATOM 12262 CG2 THR D 408 -26.129 -34.043 -80.571 1.00 77.99 C +ATOM 12263 N PRO D 409 -26.126 -35.887 -76.892 1.00 74.36 N +ATOM 12264 CA PRO D 409 -26.460 -36.370 -75.535 1.00 82.51 C +ATOM 12265 C PRO D 409 -27.882 -36.898 -75.403 1.00 89.50 C +ATOM 12266 O PRO D 409 -28.076 -37.947 -74.768 1.00 92.42 O +ATOM 12267 CB PRO D 409 -26.233 -35.133 -74.645 1.00 78.27 C +ATOM 12268 CG PRO D 409 -25.989 -33.978 -75.589 1.00 79.58 C +ATOM 12269 CD PRO D 409 -25.443 -34.582 -76.841 1.00 73.22 C +ATOM 12270 N PRO D 410 -28.903 -36.242 -75.961 1.00 81.63 N +ATOM 12271 CA PRO D 410 -30.271 -36.741 -75.747 1.00 72.92 C +ATOM 12272 C PRO D 410 -30.813 -37.633 -76.856 1.00 71.95 C +ATOM 12273 O PRO D 410 -31.941 -38.112 -76.718 1.00 72.89 O +ATOM 12274 CB PRO D 410 -31.076 -35.440 -75.670 1.00 65.78 C +ATOM 12275 CG PRO D 410 -30.325 -34.482 -76.567 1.00 74.36 C +ATOM 12276 CD PRO D 410 -28.950 -35.055 -76.835 1.00 70.72 C +ATOM 12277 N TYR D 411 -30.056 -37.877 -77.926 1.00 72.67 N +ATOM 12278 CA TYR D 411 -30.539 -38.662 -79.054 1.00 70.28 C +ATOM 12279 C TYR D 411 -29.892 -40.035 -79.130 1.00 69.77 C +ATOM 12280 O TYR D 411 -30.147 -40.776 -80.084 1.00 71.39 O +ATOM 12281 CB TYR D 411 -30.312 -37.921 -80.372 1.00 67.48 C +ATOM 12282 CG TYR D 411 -31.176 -36.702 -80.597 1.00 58.79 C +ATOM 12283 CD1 TYR D 411 -31.679 -35.965 -79.537 1.00 67.00 C +ATOM 12284 CD2 TYR D 411 -31.476 -36.282 -81.879 1.00 57.35 C +ATOM 12285 CE1 TYR D 411 -32.460 -34.849 -79.746 1.00 63.77 C +ATOM 12286 CE2 TYR D 411 -32.251 -35.171 -82.096 1.00 62.17 C +ATOM 12287 CZ TYR D 411 -32.742 -34.455 -81.030 1.00 58.84 C +ATOM 12288 OH TYR D 411 -33.519 -33.341 -81.254 1.00 54.71 O +ATOM 12289 N ASP D 412 -29.071 -40.398 -78.154 1.00 73.16 N +ATOM 12290 CA ASP D 412 -28.546 -41.751 -78.049 1.00 74.43 C +ATOM 12291 C ASP D 412 -29.133 -42.435 -76.821 1.00 71.79 C +ATOM 12292 O ASP D 412 -28.512 -43.309 -76.216 1.00 77.19 O +ATOM 12293 CB ASP D 412 -27.018 -41.741 -78.012 1.00 77.65 C +ATOM 12294 CG ASP D 412 -26.462 -41.096 -76.752 1.00 82.67 C +ATOM 12295 OD1 ASP D 412 -27.180 -40.289 -76.119 1.00 80.49 O +ATOM 12296 OD2 ASP D 412 -25.290 -41.367 -76.415 1.00 81.96 O +ATOM 12297 N ARG D 413 -30.351 -42.044 -76.470 1.00 66.80 N +ATOM 12298 CA ARG D 413 -31.106 -42.640 -75.378 1.00 74.49 C +ATOM 12299 C ARG D 413 -32.568 -42.654 -75.813 1.00 75.39 C +ATOM 12300 O ARG D 413 -32.880 -42.640 -77.009 1.00 75.20 O +ATOM 12301 CB ARG D 413 -30.854 -41.874 -74.067 1.00 82.27 C +ATOM 12302 CG ARG D 413 -30.213 -42.701 -72.960 1.00 89.07 C +ATOM 12303 CD ARG D 413 -29.173 -41.893 -72.187 1.00 93.47 C +ATOM 12304 NE ARG D 413 -28.522 -42.689 -71.145 1.00116.74 N +ATOM 12305 CZ ARG D 413 -27.393 -42.344 -70.529 1.00106.28 C +ATOM 12306 NH1 ARG D 413 -26.777 -41.213 -70.853 1.00101.08 N +ATOM 12307 NH2 ARG D 413 -26.877 -43.133 -69.593 1.00 91.80 N +ATOM 12308 N GLY D 414 -33.477 -42.683 -74.848 1.00 74.78 N +ATOM 12309 CA GLY D 414 -34.871 -42.770 -75.210 1.00 72.47 C +ATOM 12310 C GLY D 414 -35.165 -44.084 -75.933 1.00 76.02 C +ATOM 12311 O GLY D 414 -34.351 -45.007 -75.922 1.00 75.00 O +ATOM 12312 N THR D 415 -36.339 -44.186 -76.582 1.00 78.67 N +ATOM 12313 CA THR D 415 -37.511 -43.275 -76.696 1.00 75.47 C +ATOM 12314 C THR D 415 -37.266 -42.109 -77.668 1.00 76.08 C +ATOM 12315 O THR D 415 -38.070 -41.892 -78.575 1.00 77.09 O +ATOM 12316 CB THR D 415 -38.032 -42.723 -75.322 1.00 80.02 C +ATOM 12317 OG1 THR D 415 -37.898 -43.729 -74.310 1.00 79.72 O +ATOM 12318 CG2 THR D 415 -39.504 -42.344 -75.420 1.00 61.59 C +ATOM 12319 N ARG D 416 -36.182 -41.356 -77.500 1.00 75.87 N +ATOM 12320 CA ARG D 416 -35.857 -40.338 -78.488 1.00 75.66 C +ATOM 12321 C ARG D 416 -35.398 -41.006 -79.785 1.00 79.92 C +ATOM 12322 O ARG D 416 -35.220 -42.227 -79.853 1.00 87.40 O +ATOM 12323 CB ARG D 416 -34.787 -39.388 -77.953 1.00 81.28 C +ATOM 12324 CG ARG D 416 -34.824 -38.005 -78.591 1.00 76.49 C +ATOM 12325 CD ARG D 416 -36.162 -37.315 -78.348 1.00 71.53 C +ATOM 12326 NE ARG D 416 -36.089 -36.328 -77.272 1.00 61.66 N +ATOM 12327 CZ ARG D 416 -36.494 -36.543 -76.024 1.00 67.47 C +ATOM 12328 NH1 ARG D 416 -37.010 -37.715 -75.680 1.00 68.72 N +ATOM 12329 NH2 ARG D 416 -36.385 -35.583 -75.116 1.00 64.89 N +ATOM 12330 N LEU D 417 -35.190 -40.186 -80.821 1.00 70.99 N +ATOM 12331 CA LEU D 417 -35.036 -40.654 -82.199 1.00 68.46 C +ATOM 12332 C LEU D 417 -36.298 -41.355 -82.672 1.00 65.25 C +ATOM 12333 O LEU D 417 -36.887 -40.968 -83.685 1.00 63.97 O +ATOM 12334 CB LEU D 417 -33.839 -41.593 -82.363 1.00 65.87 C +ATOM 12335 CG LEU D 417 -32.566 -40.987 -82.941 1.00 76.59 C +ATOM 12336 CD1 LEU D 417 -31.452 -42.024 -82.967 1.00 86.82 C +ATOM 12337 CD2 LEU D 417 -32.849 -40.456 -84.337 1.00 58.83 C +ATOM 12338 N LEU D 418 -36.693 -42.411 -81.960 1.00 71.36 N +ATOM 12339 CA LEU D 418 -37.959 -43.077 -82.243 1.00 74.30 C +ATOM 12340 C LEU D 418 -39.131 -42.107 -82.134 1.00 72.22 C +ATOM 12341 O LEU D 418 -40.033 -42.108 -82.981 1.00 71.21 O +ATOM 12342 CB LEU D 418 -38.152 -44.266 -81.298 1.00 78.32 C +ATOM 12343 CG LEU D 418 -37.354 -45.559 -81.515 1.00 77.16 C +ATOM 12344 CD1 LEU D 418 -37.827 -46.231 -82.787 1.00 65.24 C +ATOM 12345 CD2 LEU D 418 -35.828 -45.382 -81.512 1.00 73.05 C +ATOM 12346 N ASP D 419 -39.159 -41.299 -81.069 1.00 65.77 N +ATOM 12347 CA ASP D 419 -40.202 -40.286 -80.940 1.00 67.40 C +ATOM 12348 C ASP D 419 -40.216 -39.345 -82.140 1.00 63.46 C +ATOM 12349 O ASP D 419 -41.280 -39.054 -82.698 1.00 61.62 O +ATOM 12350 CB ASP D 419 -40.031 -39.518 -79.632 1.00 71.54 C +ATOM 12351 CG ASP D 419 -40.600 -40.273 -78.443 1.00 76.16 C +ATOM 12352 OD1 ASP D 419 -41.498 -41.123 -78.646 1.00 65.29 O +ATOM 12353 OD2 ASP D 419 -40.146 -40.017 -77.311 1.00 83.04 O +ATOM 12354 N ILE D 420 -39.042 -38.857 -82.550 1.00 58.67 N +ATOM 12355 CA ILE D 420 -38.959 -38.036 -83.754 1.00 53.14 C +ATOM 12356 C ILE D 420 -39.502 -38.800 -84.952 1.00 57.96 C +ATOM 12357 O ILE D 420 -40.205 -38.238 -85.800 1.00 59.06 O +ATOM 12358 CB ILE D 420 -37.505 -37.586 -83.987 1.00 48.28 C +ATOM 12359 CG1 ILE D 420 -36.991 -36.838 -82.761 1.00 54.99 C +ATOM 12360 CG2 ILE D 420 -37.386 -36.744 -85.241 1.00 38.00 C +ATOM 12361 CD1 ILE D 420 -35.504 -36.660 -82.766 1.00 63.29 C +ATOM 12362 N MET D 421 -39.185 -40.095 -85.039 1.00 58.57 N +ATOM 12363 CA MET D 421 -39.692 -40.909 -86.136 1.00 55.11 C +ATOM 12364 C MET D 421 -41.214 -40.949 -86.127 1.00 57.11 C +ATOM 12365 O MET D 421 -41.857 -40.729 -87.162 1.00 51.90 O +ATOM 12366 CB MET D 421 -39.109 -42.316 -86.061 1.00 53.62 C +ATOM 12367 CG MET D 421 -37.606 -42.366 -86.283 1.00 54.03 C +ATOM 12368 SD MET D 421 -37.020 -41.535 -87.775 1.00 46.94 S +ATOM 12369 CE MET D 421 -35.968 -40.286 -87.047 1.00 54.84 C +ATOM 12370 N ASP D 422 -41.812 -41.194 -84.955 1.00 56.27 N +ATOM 12371 CA ASP D 422 -43.268 -41.159 -84.858 1.00 58.30 C +ATOM 12372 C ASP D 422 -43.814 -39.809 -85.301 1.00 56.69 C +ATOM 12373 O ASP D 422 -44.903 -39.734 -85.881 1.00 51.93 O +ATOM 12374 CB ASP D 422 -43.718 -41.464 -83.424 1.00 57.92 C +ATOM 12375 CG ASP D 422 -43.432 -42.900 -83.000 1.00 61.78 C +ATOM 12376 OD1 ASP D 422 -42.865 -43.669 -83.806 1.00 56.98 O +ATOM 12377 OD2 ASP D 422 -43.804 -43.266 -81.861 1.00 61.94 O +ATOM 12378 N MET D 423 -43.033 -38.749 -85.118 1.00 54.84 N +ATOM 12379 CA MET D 423 -43.452 -37.411 -85.499 1.00 49.88 C +ATOM 12380 C MET D 423 -43.160 -37.123 -86.962 1.00 51.75 C +ATOM 12381 O MET D 423 -44.012 -36.569 -87.662 1.00 54.91 O +ATOM 12382 CB MET D 423 -42.760 -36.377 -84.605 1.00 47.08 C +ATOM 12383 CG MET D 423 -42.670 -34.980 -85.193 1.00 50.96 C +ATOM 12384 SD MET D 423 -41.624 -33.881 -84.207 1.00 46.11 S +ATOM 12385 CE MET D 423 -42.811 -33.267 -83.016 1.00 62.57 C +ATOM 12386 N THR D 424 -41.981 -37.505 -87.454 1.00 49.44 N +ATOM 12387 CA THR D 424 -41.663 -37.193 -88.841 1.00 53.88 C +ATOM 12388 C THR D 424 -42.541 -37.987 -89.802 1.00 58.10 C +ATOM 12389 O THR D 424 -42.839 -37.513 -90.905 1.00 54.57 O +ATOM 12390 CB THR D 424 -40.175 -37.433 -89.113 1.00 54.11 C +ATOM 12391 OG1 THR D 424 -39.861 -37.043 -90.457 1.00 59.71 O +ATOM 12392 CG2 THR D 424 -39.822 -38.888 -88.930 1.00 56.92 C +ATOM 12393 N ILE D 425 -42.995 -39.173 -89.394 1.00 57.16 N +ATOM 12394 CA ILE D 425 -43.998 -39.876 -90.185 1.00 58.73 C +ATOM 12395 C ILE D 425 -45.312 -39.106 -90.163 1.00 59.39 C +ATOM 12396 O ILE D 425 -45.988 -38.972 -91.191 1.00 53.20 O +ATOM 12397 CB ILE D 425 -44.171 -41.315 -89.669 1.00 56.02 C +ATOM 12398 CG1 ILE D 425 -42.881 -42.109 -89.870 1.00 57.69 C +ATOM 12399 CG2 ILE D 425 -45.315 -42.006 -90.386 1.00 53.33 C +ATOM 12400 CD1 ILE D 425 -42.976 -43.533 -89.396 1.00 53.47 C +ATOM 12401 N PHE D 426 -45.679 -38.578 -88.989 1.00 59.06 N +ATOM 12402 CA PHE D 426 -46.869 -37.741 -88.848 1.00 56.03 C +ATOM 12403 C PHE D 426 -46.804 -36.531 -89.780 1.00 57.07 C +ATOM 12404 O PHE D 426 -47.750 -36.258 -90.529 1.00 56.28 O +ATOM 12405 CB PHE D 426 -47.000 -37.312 -87.380 1.00 54.54 C +ATOM 12406 CG PHE D 426 -48.307 -36.635 -87.022 1.00 55.29 C +ATOM 12407 CD1 PHE D 426 -49.322 -36.467 -87.945 1.00 60.21 C +ATOM 12408 CD2 PHE D 426 -48.497 -36.141 -85.742 1.00 49.00 C +ATOM 12409 CE1 PHE D 426 -50.503 -35.833 -87.591 1.00 55.85 C +ATOM 12410 CE2 PHE D 426 -49.671 -35.508 -85.387 1.00 44.86 C +ATOM 12411 CZ PHE D 426 -50.674 -35.353 -86.311 1.00 45.69 C +ATOM 12412 N ASP D 427 -45.696 -35.786 -89.740 1.00 54.93 N +ATOM 12413 CA ASP D 427 -45.598 -34.565 -90.536 1.00 58.99 C +ATOM 12414 C ASP D 427 -45.646 -34.847 -92.031 1.00 56.06 C +ATOM 12415 O ASP D 427 -46.157 -34.023 -92.800 1.00 51.51 O +ATOM 12416 CB ASP D 427 -44.318 -33.809 -90.189 1.00 61.40 C +ATOM 12417 CG ASP D 427 -44.383 -33.155 -88.829 1.00 63.91 C +ATOM 12418 OD1 ASP D 427 -45.500 -32.777 -88.408 1.00 61.62 O +ATOM 12419 OD2 ASP D 427 -43.320 -33.020 -88.185 1.00 58.48 O +ATOM 12420 N PHE D 428 -45.121 -35.993 -92.466 1.00 56.96 N +ATOM 12421 CA PHE D 428 -45.154 -36.305 -93.890 1.00 58.07 C +ATOM 12422 C PHE D 428 -46.570 -36.618 -94.353 1.00 57.16 C +ATOM 12423 O PHE D 428 -46.974 -36.211 -95.449 1.00 56.33 O +ATOM 12424 CB PHE D 428 -44.227 -37.477 -94.200 1.00 53.30 C +ATOM 12425 CG PHE D 428 -44.197 -37.854 -95.654 1.00 48.39 C +ATOM 12426 CD1 PHE D 428 -43.499 -37.086 -96.567 1.00 55.62 C +ATOM 12427 CD2 PHE D 428 -44.870 -38.971 -96.106 1.00 49.85 C +ATOM 12428 CE1 PHE D 428 -43.472 -37.428 -97.905 1.00 59.97 C +ATOM 12429 CE2 PHE D 428 -44.848 -39.318 -97.440 1.00 55.44 C +ATOM 12430 CZ PHE D 428 -44.148 -38.545 -98.343 1.00 58.02 C +ATOM 12431 N LEU D 429 -47.342 -37.329 -93.528 1.00 52.21 N +ATOM 12432 CA LEU D 429 -48.721 -37.632 -93.889 1.00 51.96 C +ATOM 12433 C LEU D 429 -49.538 -36.364 -94.096 1.00 54.29 C +ATOM 12434 O LEU D 429 -50.455 -36.346 -94.923 1.00 54.26 O +ATOM 12435 CB LEU D 429 -49.354 -38.508 -92.813 1.00 51.24 C +ATOM 12436 CG LEU D 429 -48.661 -39.854 -92.612 1.00 46.13 C +ATOM 12437 CD1 LEU D 429 -49.354 -40.646 -91.520 1.00 46.56 C +ATOM 12438 CD2 LEU D 429 -48.625 -40.633 -93.911 1.00 50.89 C +ATOM 12439 N MET D 430 -49.220 -35.296 -93.368 1.00 52.96 N +ATOM 12440 CA MET D 430 -49.919 -34.030 -93.538 1.00 47.98 C +ATOM 12441 C MET D 430 -49.225 -33.099 -94.520 1.00 50.45 C +ATOM 12442 O MET D 430 -49.883 -32.235 -95.115 1.00 48.61 O +ATOM 12443 CB MET D 430 -50.062 -33.330 -92.189 1.00 45.21 C +ATOM 12444 CG MET D 430 -50.689 -34.189 -91.127 1.00 40.32 C +ATOM 12445 SD MET D 430 -51.081 -33.198 -89.681 1.00 52.72 S +ATOM 12446 CE MET D 430 -49.448 -32.648 -89.187 1.00 56.72 C +ATOM 12447 N GLY D 431 -47.916 -33.253 -94.707 1.00 50.37 N +ATOM 12448 CA GLY D 431 -47.157 -32.290 -95.479 1.00 57.01 C +ATOM 12449 C GLY D 431 -46.687 -31.085 -94.699 1.00 57.32 C +ATOM 12450 O GLY D 431 -46.357 -30.057 -95.300 1.00 57.20 O +ATOM 12451 N ASN D 432 -46.636 -31.187 -93.373 1.00 53.85 N +ATOM 12452 CA ASN D 432 -46.271 -30.074 -92.499 1.00 52.31 C +ATOM 12453 C ASN D 432 -44.751 -29.986 -92.423 1.00 56.96 C +ATOM 12454 O ASN D 432 -44.113 -30.689 -91.634 1.00 59.03 O +ATOM 12455 CB ASN D 432 -46.894 -30.277 -91.122 1.00 52.51 C +ATOM 12456 CG ASN D 432 -46.398 -29.279 -90.094 1.00 56.86 C +ATOM 12457 OD1 ASN D 432 -46.264 -28.088 -90.374 1.00 59.20 O +ATOM 12458 ND2 ASN D 432 -46.138 -29.763 -88.886 1.00 54.53 N +ATOM 12459 N MET D 433 -44.162 -29.101 -93.230 1.00 50.41 N +ATOM 12460 CA MET D 433 -42.720 -28.893 -93.236 1.00 52.65 C +ATOM 12461 C MET D 433 -42.294 -27.740 -92.331 1.00 54.43 C +ATOM 12462 O MET D 433 -41.196 -27.201 -92.498 1.00 53.97 O +ATOM 12463 CB MET D 433 -42.220 -28.661 -94.668 1.00 52.89 C +ATOM 12464 CG MET D 433 -43.171 -27.861 -95.569 1.00 58.92 C +ATOM 12465 SD MET D 433 -42.598 -27.666 -97.287 1.00 57.64 S +ATOM 12466 CE MET D 433 -44.105 -27.122 -98.100 1.00 46.43 C +ATOM 12467 N ASP D 434 -43.133 -27.371 -91.362 1.00 57.98 N +ATOM 12468 CA ASP D 434 -42.862 -26.275 -90.440 1.00 57.59 C +ATOM 12469 C ASP D 434 -42.568 -26.776 -89.028 1.00 61.24 C +ATOM 12470 O ASP D 434 -42.818 -26.073 -88.046 1.00 64.48 O +ATOM 12471 CB ASP D 434 -44.040 -25.302 -90.423 1.00 65.00 C +ATOM 12472 CG ASP D 434 -43.660 -23.926 -89.909 1.00 72.26 C +ATOM 12473 OD1 ASP D 434 -42.470 -23.559 -90.004 1.00 77.75 O +ATOM 12474 OD2 ASP D 434 -44.555 -23.213 -89.407 1.00 79.64 O +ATOM 12475 N ARG D 435 -42.047 -27.996 -88.911 1.00 57.64 N +ATOM 12476 CA ARG D 435 -41.752 -28.588 -87.608 1.00 50.76 C +ATOM 12477 C ARG D 435 -40.306 -28.264 -87.237 1.00 57.08 C +ATOM 12478 O ARG D 435 -39.387 -29.069 -87.396 1.00 62.20 O +ATOM 12479 CB ARG D 435 -42.007 -30.087 -87.645 1.00 46.56 C +ATOM 12480 CG ARG D 435 -41.861 -30.766 -86.310 1.00 48.01 C +ATOM 12481 CD ARG D 435 -43.018 -30.444 -85.397 1.00 43.42 C +ATOM 12482 NE ARG D 435 -44.261 -31.014 -85.894 1.00 38.04 N +ATOM 12483 CZ ARG D 435 -45.425 -30.903 -85.269 1.00 43.23 C +ATOM 12484 NH1 ARG D 435 -45.498 -30.247 -84.122 1.00 46.35 N +ATOM 12485 NH2 ARG D 435 -46.513 -31.449 -85.787 1.00 51.99 N +ATOM 12486 N HIS D 436 -40.113 -27.070 -86.686 1.00 60.24 N +ATOM 12487 CA HIS D 436 -38.786 -26.621 -86.288 1.00 62.33 C +ATOM 12488 C HIS D 436 -38.528 -26.761 -84.796 1.00 61.62 C +ATOM 12489 O HIS D 436 -37.389 -26.562 -84.360 1.00 60.96 O +ATOM 12490 CB HIS D 436 -38.578 -25.155 -86.701 1.00 67.05 C +ATOM 12491 CG HIS D 436 -39.634 -24.214 -86.192 1.00 72.48 C +ATOM 12492 ND1 HIS D 436 -40.628 -24.602 -85.319 1.00 73.82 N +ATOM 12493 CD2 HIS D 436 -39.847 -22.899 -86.437 1.00 79.32 C +ATOM 12494 CE1 HIS D 436 -41.407 -23.570 -85.048 1.00 76.34 C +ATOM 12495 NE2 HIS D 436 -40.955 -22.524 -85.716 1.00 89.12 N +ATOM 12496 N HIS D 437 -39.541 -27.121 -84.015 1.00 60.28 N +ATOM 12497 CA HIS D 437 -39.431 -27.187 -82.568 1.00 52.78 C +ATOM 12498 C HIS D 437 -40.417 -28.232 -82.067 1.00 45.04 C +ATOM 12499 O HIS D 437 -41.537 -28.329 -82.577 1.00 43.60 O +ATOM 12500 CB HIS D 437 -39.744 -25.828 -81.920 1.00 63.66 C +ATOM 12501 CG HIS D 437 -38.702 -24.773 -82.147 1.00 65.40 C +ATOM 12502 ND1 HIS D 437 -37.380 -25.065 -82.411 1.00 65.76 N +ATOM 12503 CD2 HIS D 437 -38.786 -23.421 -82.115 1.00 61.63 C +ATOM 12504 CE1 HIS D 437 -36.700 -23.940 -82.546 1.00 59.69 C +ATOM 12505 NE2 HIS D 437 -37.530 -22.927 -82.370 1.00 57.00 N +ATOM 12506 N TYR D 438 -40.027 -28.968 -81.032 1.00 41.59 N +ATOM 12507 CA TYR D 438 -40.918 -29.955 -80.431 1.00 50.67 C +ATOM 12508 C TYR D 438 -40.826 -29.828 -78.921 1.00 50.73 C +ATOM 12509 O TYR D 438 -39.732 -29.904 -78.355 1.00 53.24 O +ATOM 12510 CB TYR D 438 -40.597 -31.389 -80.885 1.00 52.53 C +ATOM 12511 CG TYR D 438 -39.197 -31.888 -80.583 1.00 55.79 C +ATOM 12512 CD1 TYR D 438 -38.138 -31.599 -81.430 1.00 57.14 C +ATOM 12513 CD2 TYR D 438 -38.943 -32.671 -79.463 1.00 53.85 C +ATOM 12514 CE1 TYR D 438 -36.862 -32.062 -81.160 1.00 57.10 C +ATOM 12515 CE2 TYR D 438 -37.674 -33.137 -79.184 1.00 51.43 C +ATOM 12516 CZ TYR D 438 -36.639 -32.832 -80.036 1.00 55.76 C +ATOM 12517 OH TYR D 438 -35.373 -33.294 -79.760 1.00 59.50 O +ATOM 12518 N GLU D 439 -41.961 -29.559 -78.285 1.00 45.55 N +ATOM 12519 CA GLU D 439 -41.965 -29.362 -76.849 1.00 49.23 C +ATOM 12520 C GLU D 439 -42.048 -30.705 -76.120 1.00 46.47 C +ATOM 12521 O GLU D 439 -42.382 -31.741 -76.697 1.00 46.26 O +ATOM 12522 CB GLU D 439 -43.117 -28.440 -76.443 1.00 62.15 C +ATOM 12523 CG GLU D 439 -42.964 -26.980 -76.900 1.00 58.29 C +ATOM 12524 CD GLU D 439 -44.100 -26.095 -76.392 1.00 60.76 C +ATOM 12525 OE1 GLU D 439 -44.381 -26.130 -75.171 1.00 51.08 O +ATOM 12526 OE2 GLU D 439 -44.707 -25.361 -77.204 1.00 60.36 O +ATOM 12527 N THR D 440 -41.785 -30.656 -74.813 1.00 52.12 N +ATOM 12528 CA THR D 440 -41.811 -31.821 -73.934 1.00 45.67 C +ATOM 12529 C THR D 440 -42.534 -31.446 -72.645 1.00 48.52 C +ATOM 12530 O THR D 440 -43.504 -30.686 -72.684 1.00 56.07 O +ATOM 12531 CB THR D 440 -40.392 -32.305 -73.635 1.00 44.97 C +ATOM 12532 OG1 THR D 440 -39.554 -32.039 -74.762 1.00 44.16 O +ATOM 12533 CG2 THR D 440 -40.386 -33.793 -73.381 1.00 57.58 C +ATOM 12534 N PHE D 441 -42.096 -31.961 -71.496 1.00 44.82 N +ATOM 12535 CA PHE D 441 -42.790 -31.628 -70.257 1.00 49.17 C +ATOM 12536 C PHE D 441 -41.847 -31.433 -69.076 1.00 54.81 C +ATOM 12537 O PHE D 441 -42.326 -31.293 -67.943 1.00 58.67 O +ATOM 12538 CB PHE D 441 -43.850 -32.687 -69.914 1.00 44.00 C +ATOM 12539 CG PHE D 441 -45.223 -32.362 -70.442 1.00 38.00 C +ATOM 12540 CD1 PHE D 441 -46.039 -31.453 -69.795 1.00 38.00 C +ATOM 12541 CD2 PHE D 441 -45.684 -32.949 -71.605 1.00 41.07 C +ATOM 12542 CE1 PHE D 441 -47.300 -31.152 -70.292 1.00 41.74 C +ATOM 12543 CE2 PHE D 441 -46.941 -32.650 -72.104 1.00 39.61 C +ATOM 12544 CZ PHE D 441 -47.750 -31.752 -71.447 1.00 38.00 C +ATOM 12545 N GLU D 442 -40.531 -31.420 -69.296 1.00 51.13 N +ATOM 12546 CA GLU D 442 -39.571 -30.978 -68.287 1.00 57.33 C +ATOM 12547 C GLU D 442 -39.632 -31.806 -67.008 1.00 62.29 C +ATOM 12548 O GLU D 442 -38.656 -32.478 -66.656 1.00 64.99 O +ATOM 12549 CB GLU D 442 -39.780 -29.497 -67.953 1.00 63.59 C +ATOM 12550 CG GLU D 442 -38.650 -28.586 -68.411 1.00 70.57 C +ATOM 12551 CD GLU D 442 -37.398 -28.703 -67.552 1.00 84.74 C +ATOM 12552 OE1 GLU D 442 -36.281 -28.606 -68.103 1.00 72.72 O +ATOM 12553 OE2 GLU D 442 -37.536 -28.914 -66.323 1.00 94.74 O +ATOM 12554 N LYS D 443 -40.767 -31.764 -66.300 1.00 64.88 N +ATOM 12555 CA LYS D 443 -40.895 -32.467 -65.025 1.00 73.77 C +ATOM 12556 C LYS D 443 -40.727 -33.971 -65.170 1.00 76.99 C +ATOM 12557 O LYS D 443 -40.612 -34.671 -64.157 1.00 85.15 O +ATOM 12558 CB LYS D 443 -42.258 -32.160 -64.380 1.00 80.06 C +ATOM 12559 CG LYS D 443 -42.351 -32.511 -62.887 1.00 99.04 C +ATOM 12560 CD LYS D 443 -43.690 -32.104 -62.280 1.00 99.70 C +ATOM 12561 CE LYS D 443 -43.774 -32.450 -60.793 1.00 98.33 C +ATOM 12562 NZ LYS D 443 -45.099 -32.089 -60.203 1.00 87.79 N +ATOM 12563 N PHE D 444 -40.661 -34.471 -66.400 1.00 72.28 N +ATOM 12564 CA PHE D 444 -40.524 -35.889 -66.693 1.00 65.02 C +ATOM 12565 C PHE D 444 -39.089 -36.310 -66.976 1.00 65.46 C +ATOM 12566 O PHE D 444 -38.654 -37.370 -66.516 1.00 71.17 O +ATOM 12567 CB PHE D 444 -41.397 -36.244 -67.895 1.00 51.64 C +ATOM 12568 CG PHE D 444 -42.864 -36.296 -67.587 1.00 53.13 C +ATOM 12569 CD1 PHE D 444 -43.308 -36.723 -66.349 1.00 60.41 C +ATOM 12570 CD2 PHE D 444 -43.801 -35.917 -68.533 1.00 52.09 C +ATOM 12571 CE1 PHE D 444 -44.653 -36.774 -66.061 1.00 62.94 C +ATOM 12572 CE2 PHE D 444 -45.148 -35.968 -68.252 1.00 52.87 C +ATOM 12573 CZ PHE D 444 -45.575 -36.397 -67.014 1.00 59.68 C +ATOM 12574 N GLY D 445 -38.341 -35.498 -67.699 1.00 57.57 N +ATOM 12575 CA GLY D 445 -37.014 -35.847 -68.137 1.00 52.93 C +ATOM 12576 C GLY D 445 -36.981 -36.149 -69.620 1.00 58.38 C +ATOM 12577 O GLY D 445 -37.903 -35.833 -70.374 1.00 60.80 O +ATOM 12578 N ASN D 446 -35.904 -36.813 -70.034 1.00 66.40 N +ATOM 12579 CA ASN D 446 -35.659 -37.104 -71.441 1.00 69.64 C +ATOM 12580 C ASN D 446 -36.334 -38.397 -71.907 1.00 73.60 C +ATOM 12581 O ASN D 446 -35.955 -38.946 -72.949 1.00 67.05 O +ATOM 12582 CB ASN D 446 -34.146 -37.167 -71.695 1.00 64.39 C +ATOM 12583 CG ASN D 446 -33.476 -35.795 -71.638 1.00 56.89 C +ATOM 12584 OD1 ASN D 446 -34.019 -34.811 -72.125 1.00 60.83 O +ATOM 12585 ND2 ASN D 446 -32.292 -35.731 -71.036 1.00 49.70 N +ATOM 12586 N ASP D 447 -37.346 -38.870 -71.177 1.00 74.53 N +ATOM 12587 CA ASP D 447 -37.992 -40.157 -71.410 1.00 69.19 C +ATOM 12588 C ASP D 447 -39.491 -40.007 -71.610 1.00 65.80 C +ATOM 12589 O ASP D 447 -40.283 -40.738 -71.014 1.00 71.54 O +ATOM 12590 CB ASP D 447 -37.743 -41.131 -70.259 1.00 76.63 C +ATOM 12591 CG ASP D 447 -36.272 -41.373 -69.993 1.00 89.34 C +ATOM 12592 OD1 ASP D 447 -35.480 -41.425 -70.964 1.00 86.23 O +ATOM 12593 OD2 ASP D 447 -35.914 -41.516 -68.804 1.00 89.11 O +ATOM 12594 N THR D 448 -39.913 -39.042 -72.421 1.00 57.87 N +ATOM 12595 CA THR D 448 -41.334 -38.841 -72.654 1.00 62.85 C +ATOM 12596 C THR D 448 -41.597 -38.570 -74.119 1.00 59.24 C +ATOM 12597 O THR D 448 -40.679 -38.478 -74.939 1.00 59.99 O +ATOM 12598 CB THR D 448 -41.899 -37.698 -71.821 1.00 59.65 C +ATOM 12599 OG1 THR D 448 -40.917 -36.661 -71.711 1.00 69.53 O +ATOM 12600 CG2 THR D 448 -42.291 -38.202 -70.476 1.00 66.32 C +ATOM 12601 N PHE D 449 -42.879 -38.435 -74.430 1.00 54.05 N +ATOM 12602 CA PHE D 449 -43.310 -38.180 -75.789 1.00 56.52 C +ATOM 12603 C PHE D 449 -43.090 -36.717 -76.138 1.00 49.24 C +ATOM 12604 O PHE D 449 -42.690 -35.898 -75.307 1.00 51.93 O +ATOM 12605 CB PHE D 449 -44.773 -38.566 -75.954 1.00 58.26 C +ATOM 12606 CG PHE D 449 -45.720 -37.642 -75.259 1.00 48.36 C +ATOM 12607 CD1 PHE D 449 -45.848 -37.670 -73.884 1.00 45.35 C +ATOM 12608 CD2 PHE D 449 -46.511 -36.772 -75.984 1.00 52.12 C +ATOM 12609 CE1 PHE D 449 -46.730 -36.838 -73.245 1.00 48.03 C +ATOM 12610 CE2 PHE D 449 -47.398 -35.937 -75.347 1.00 52.77 C +ATOM 12611 CZ PHE D 449 -47.508 -35.971 -73.976 1.00 46.16 C +ATOM 12612 N ILE D 450 -43.397 -36.386 -77.382 1.00 45.25 N +ATOM 12613 CA ILE D 450 -43.263 -35.036 -77.898 1.00 46.72 C +ATOM 12614 C ILE D 450 -44.650 -34.541 -78.269 1.00 47.03 C +ATOM 12615 O ILE D 450 -45.413 -35.246 -78.937 1.00 51.45 O +ATOM 12616 CB ILE D 450 -42.292 -34.984 -79.089 1.00 41.89 C +ATOM 12617 CG1 ILE D 450 -42.666 -36.022 -80.141 1.00 51.48 C +ATOM 12618 CG2 ILE D 450 -40.885 -35.280 -78.625 1.00 42.19 C +ATOM 12619 CD1 ILE D 450 -41.616 -36.174 -81.204 1.00 62.33 C +ATOM 12620 N ILE D 451 -45.005 -33.369 -77.764 1.00 47.29 N +ATOM 12621 CA ILE D 451 -46.307 -32.780 -78.042 1.00 46.11 C +ATOM 12622 C ILE D 451 -46.274 -32.229 -79.460 1.00 48.16 C +ATOM 12623 O ILE D 451 -45.402 -31.426 -79.808 1.00 50.45 O +ATOM 12624 CB ILE D 451 -46.661 -31.685 -77.025 1.00 42.72 C +ATOM 12625 CG1 ILE D 451 -46.472 -32.199 -75.607 1.00 40.46 C +ATOM 12626 CG2 ILE D 451 -48.103 -31.271 -77.180 1.00 47.25 C +ATOM 12627 CD1 ILE D 451 -45.157 -31.828 -75.017 1.00 38.00 C +ATOM 12628 N HIS D 452 -47.189 -32.703 -80.294 1.00 44.88 N +ATOM 12629 CA HIS D 452 -47.282 -32.259 -81.680 1.00 48.24 C +ATOM 12630 C HIS D 452 -48.168 -31.012 -81.697 1.00 47.38 C +ATOM 12631 O HIS D 452 -49.397 -31.094 -81.683 1.00 46.89 O +ATOM 12632 CB HIS D 452 -47.814 -33.394 -82.552 1.00 52.36 C +ATOM 12633 CG HIS D 452 -46.982 -34.649 -82.506 1.00 51.93 C +ATOM 12634 ND1 HIS D 452 -47.485 -35.886 -82.853 1.00 49.26 N +ATOM 12635 CD2 HIS D 452 -45.678 -34.853 -82.196 1.00 49.80 C +ATOM 12636 CE1 HIS D 452 -46.535 -36.797 -82.741 1.00 46.22 C +ATOM 12637 NE2 HIS D 452 -45.427 -36.197 -82.347 1.00 42.29 N +ATOM 12638 N LEU D 453 -47.532 -29.839 -81.669 1.00 48.13 N +ATOM 12639 CA LEU D 453 -48.199 -28.542 -81.638 1.00 45.85 C +ATOM 12640 C LEU D 453 -47.964 -27.779 -82.938 1.00 53.86 C +ATOM 12641 O LEU D 453 -47.084 -28.119 -83.731 1.00 58.09 O +ATOM 12642 CB LEU D 453 -47.699 -27.712 -80.456 1.00 40.25 C +ATOM 12643 CG LEU D 453 -48.080 -28.299 -79.106 1.00 38.80 C +ATOM 12644 CD1 LEU D 453 -47.420 -27.521 -77.982 1.00 51.02 C +ATOM 12645 CD2 LEU D 453 -49.582 -28.303 -78.959 1.00 38.00 C +ATOM 12646 N ASP D 454 -48.761 -26.726 -83.140 1.00 53.90 N +ATOM 12647 CA ASP D 454 -48.677 -25.853 -84.318 1.00 63.17 C +ATOM 12648 C ASP D 454 -48.726 -26.664 -85.616 1.00 62.57 C +ATOM 12649 O ASP D 454 -47.798 -26.652 -86.430 1.00 61.66 O +ATOM 12650 CB ASP D 454 -47.410 -24.988 -84.277 1.00 71.04 C +ATOM 12651 CG ASP D 454 -47.462 -23.912 -83.206 1.00 61.70 C +ATOM 12652 OD1 ASP D 454 -47.313 -24.271 -82.021 1.00 49.46 O +ATOM 12653 OD2 ASP D 454 -47.613 -22.713 -83.550 1.00 59.25 O +ATOM 12654 N ASN D 455 -49.833 -27.378 -85.799 1.00 59.56 N +ATOM 12655 CA ASN D 455 -50.022 -28.250 -86.951 1.00 56.15 C +ATOM 12656 C ASN D 455 -50.753 -27.573 -88.103 1.00 51.36 C +ATOM 12657 O ASN D 455 -51.134 -28.250 -89.063 1.00 47.08 O +ATOM 12658 CB ASN D 455 -50.786 -29.501 -86.525 1.00 51.42 C +ATOM 12659 CG ASN D 455 -50.249 -30.089 -85.247 1.00 50.37 C +ATOM 12660 OD1 ASN D 455 -49.039 -30.216 -85.074 1.00 48.94 O +ATOM 12661 ND2 ASN D 455 -51.146 -30.431 -84.329 1.00 49.41 N +ATOM 12662 N GLY D 456 -50.949 -26.258 -88.037 1.00 50.91 N +ATOM 12663 CA GLY D 456 -51.798 -25.569 -88.991 1.00 51.75 C +ATOM 12664 C GLY D 456 -51.235 -25.447 -90.393 1.00 52.71 C +ATOM 12665 O GLY D 456 -51.965 -25.007 -91.289 1.00 49.48 O +ATOM 12666 N ARG D 457 -49.973 -25.814 -90.607 1.00 53.77 N +ATOM 12667 CA ARG D 457 -49.331 -25.655 -91.906 1.00 51.15 C +ATOM 12668 C ARG D 457 -49.471 -26.878 -92.803 1.00 48.31 C +ATOM 12669 O ARG D 457 -49.010 -26.843 -93.949 1.00 45.62 O +ATOM 12670 CB ARG D 457 -47.842 -25.330 -91.723 1.00 54.88 C +ATOM 12671 CG ARG D 457 -47.557 -24.149 -90.806 1.00 52.66 C +ATOM 12672 CD ARG D 457 -47.022 -22.960 -91.590 1.00 54.77 C +ATOM 12673 NE ARG D 457 -46.815 -21.787 -90.744 1.00 58.79 N +ATOM 12674 CZ ARG D 457 -46.246 -20.656 -91.154 1.00 66.24 C +ATOM 12675 NH1 ARG D 457 -45.817 -20.537 -92.404 1.00 62.51 N +ATOM 12676 NH2 ARG D 457 -46.106 -19.639 -90.314 1.00 70.93 N +ATOM 12677 N GLY D 458 -50.108 -27.943 -92.322 1.00 47.29 N +ATOM 12678 CA GLY D 458 -50.323 -29.127 -93.122 1.00 49.02 C +ATOM 12679 C GLY D 458 -51.544 -29.015 -94.015 1.00 53.68 C +ATOM 12680 O GLY D 458 -52.269 -28.020 -94.014 1.00 55.05 O +ATOM 12681 N PHE D 459 -51.748 -30.061 -94.817 1.00 54.85 N +ATOM 12682 CA PHE D 459 -52.900 -30.169 -95.709 1.00 51.75 C +ATOM 12683 C PHE D 459 -53.001 -28.947 -96.614 1.00 53.35 C +ATOM 12684 O PHE D 459 -54.067 -28.358 -96.800 1.00 51.58 O +ATOM 12685 CB PHE D 459 -54.192 -30.386 -94.922 1.00 43.01 C +ATOM 12686 CG PHE D 459 -54.193 -31.648 -94.119 1.00 41.47 C +ATOM 12687 CD1 PHE D 459 -54.570 -32.845 -94.698 1.00 46.10 C +ATOM 12688 CD2 PHE D 459 -53.804 -31.646 -92.796 1.00 44.74 C +ATOM 12689 CE1 PHE D 459 -54.560 -34.013 -93.974 1.00 41.71 C +ATOM 12690 CE2 PHE D 459 -53.794 -32.815 -92.066 1.00 47.55 C +ATOM 12691 CZ PHE D 459 -54.173 -33.999 -92.657 1.00 41.63 C +ATOM 12692 N GLY D 460 -51.857 -28.561 -97.172 1.00 53.96 N +ATOM 12693 CA GLY D 460 -51.806 -27.433 -98.078 1.00 61.63 C +ATOM 12694 C GLY D 460 -51.665 -27.821 -99.535 1.00 59.37 C +ATOM 12695 O GLY D 460 -51.995 -27.033-100.427 1.00 59.17 O +ATOM 12696 N LYS D 461 -51.201 -29.042 -99.792 1.00 54.71 N +ATOM 12697 CA LYS D 461 -50.974 -29.517-101.151 1.00 58.17 C +ATOM 12698 C LYS D 461 -51.413 -30.973-101.226 1.00 64.66 C +ATOM 12699 O LYS D 461 -50.895 -31.813-100.484 1.00 60.86 O +ATOM 12700 CB LYS D 461 -49.497 -29.364-101.542 1.00 57.21 C +ATOM 12701 CG LYS D 461 -48.976 -27.927-101.465 1.00 51.82 C +ATOM 12702 CD LYS D 461 -47.469 -27.822-101.688 1.00 51.15 C +ATOM 12703 CE LYS D 461 -47.090 -28.085-103.141 1.00 72.11 C +ATOM 12704 NZ LYS D 461 -47.740 -27.156-104.113 1.00 77.89 N +ATOM 12705 N HIS D 462 -52.378 -31.268-102.107 1.00 65.77 N +ATOM 12706 CA HIS D 462 -52.880 -32.628-102.274 1.00 60.29 C +ATOM 12707 C HIS D 462 -52.357 -33.315-103.525 1.00 61.54 C +ATOM 12708 O HIS D 462 -52.333 -34.548-103.570 1.00 64.72 O +ATOM 12709 CB HIS D 462 -54.415 -32.649-102.303 1.00 55.84 C +ATOM 12710 CG HIS D 462 -55.016 -31.926-103.467 1.00 59.37 C +ATOM 12711 ND1 HIS D 462 -55.621 -30.694-103.344 1.00 63.19 N +ATOM 12712 CD2 HIS D 462 -55.125 -32.268-104.772 1.00 62.49 C +ATOM 12713 CE1 HIS D 462 -56.072 -30.305-104.523 1.00 61.25 C +ATOM 12714 NE2 HIS D 462 -55.780 -31.241-105.408 1.00 66.88 N +ATOM 12715 N SER D 463 -51.948 -32.557-104.538 1.00 61.35 N +ATOM 12716 CA SER D 463 -51.334 -33.128-105.725 1.00 66.78 C +ATOM 12717 C SER D 463 -49.817 -33.199-105.609 1.00 70.96 C +ATOM 12718 O SER D 463 -49.134 -33.430-106.614 1.00 78.89 O +ATOM 12719 CB SER D 463 -51.743 -32.323-106.962 1.00 76.16 C +ATOM 12720 OG SER D 463 -51.282 -30.983-106.888 1.00 74.10 O +ATOM 12721 N HIS D 464 -49.281 -33.039-104.401 1.00 62.01 N +ATOM 12722 CA HIS D 464 -47.845 -32.955-104.182 1.00 64.49 C +ATOM 12723 C HIS D 464 -47.500 -33.686-102.893 1.00 62.28 C +ATOM 12724 O HIS D 464 -48.235 -33.593-101.906 1.00 61.58 O +ATOM 12725 CB HIS D 464 -47.403 -31.485-104.113 1.00 61.42 C +ATOM 12726 CG HIS D 464 -45.920 -31.281-104.166 1.00 65.12 C +ATOM 12727 ND1 HIS D 464 -45.055 -31.832-103.246 1.00 62.28 N +ATOM 12728 CD2 HIS D 464 -45.153 -30.557-105.016 1.00 67.40 C +ATOM 12729 CE1 HIS D 464 -43.818 -31.471-103.535 1.00 65.88 C +ATOM 12730 NE2 HIS D 464 -43.849 -30.696-104.604 1.00 70.80 N +ATOM 12731 N ASP D 465 -46.392 -34.429-102.916 1.00 66.52 N +ATOM 12732 CA ASP D 465 -45.877 -35.141-101.744 1.00 65.38 C +ATOM 12733 C ASP D 465 -44.480 -34.610-101.437 1.00 63.39 C +ATOM 12734 O ASP D 465 -43.512 -34.952-102.123 1.00 62.80 O +ATOM 12735 CB ASP D 465 -45.855 -36.652-101.975 1.00 63.79 C +ATOM 12736 CG ASP D 465 -47.212 -37.205-102.368 1.00 70.31 C +ATOM 12737 OD1 ASP D 465 -48.237 -36.610-101.971 1.00 69.42 O +ATOM 12738 OD2 ASP D 465 -47.255 -38.246-103.060 1.00 76.08 O +ATOM 12739 N GLU D 466 -44.371 -33.776-100.407 1.00 62.33 N +ATOM 12740 CA GLU D 466 -43.093 -33.172-100.038 1.00 58.34 C +ATOM 12741 C GLU D 466 -42.203 -34.227 -99.400 1.00 58.06 C +ATOM 12742 O GLU D 466 -42.352 -34.556 -98.222 1.00 53.28 O +ATOM 12743 CB GLU D 466 -43.315 -31.997 -99.094 1.00 68.05 C +ATOM 12744 CG GLU D 466 -42.034 -31.315 -98.655 1.00 64.82 C +ATOM 12745 CD GLU D 466 -41.311 -30.626 -99.796 1.00 66.66 C +ATOM 12746 OE1 GLU D 466 -41.932 -30.386-100.856 1.00 68.29 O +ATOM 12747 OE2 GLU D 466 -40.112 -30.324 -99.631 1.00 68.92 O +ATOM 12748 N MET D 467 -41.264 -34.760-100.183 1.00 62.84 N +ATOM 12749 CA MET D 467 -40.382 -35.814 -99.696 1.00 64.37 C +ATOM 12750 C MET D 467 -39.328 -35.303 -98.721 1.00 57.41 C +ATOM 12751 O MET D 467 -38.697 -36.118 -98.039 1.00 55.56 O +ATOM 12752 CB MET D 467 -39.710 -36.523-100.876 1.00 64.82 C +ATOM 12753 CG MET D 467 -40.677 -37.183-101.863 1.00 64.57 C +ATOM 12754 SD MET D 467 -41.757 -38.421-101.106 1.00 65.50 S +ATOM 12755 CE MET D 467 -40.531 -39.558-100.465 1.00 57.12 C +ATOM 12756 N SER D 468 -39.123 -33.986 -98.636 1.00 56.30 N +ATOM 12757 CA SER D 468 -38.100 -33.456 -97.742 1.00 52.46 C +ATOM 12758 C SER D 468 -38.399 -33.782 -96.287 1.00 57.22 C +ATOM 12759 O SER D 468 -37.473 -33.894 -95.476 1.00 65.29 O +ATOM 12760 CB SER D 468 -37.982 -31.943 -97.916 1.00 53.65 C +ATOM 12761 OG SER D 468 -37.683 -31.603 -99.256 1.00 68.26 O +ATOM 12762 N ILE D 469 -39.676 -33.947 -95.938 1.00 55.12 N +ATOM 12763 CA ILE D 469 -40.036 -34.254 -94.557 1.00 55.08 C +ATOM 12764 C ILE D 469 -39.559 -35.643 -94.166 1.00 57.27 C +ATOM 12765 O ILE D 469 -39.203 -35.885 -93.005 1.00 49.66 O +ATOM 12766 CB ILE D 469 -41.555 -34.109 -94.372 1.00 50.36 C +ATOM 12767 CG1 ILE D 469 -42.004 -32.727 -94.837 1.00 53.11 C +ATOM 12768 CG2 ILE D 469 -41.946 -34.347 -92.922 1.00 50.50 C +ATOM 12769 CD1 ILE D 469 -43.495 -32.546 -94.820 1.00 58.11 C +ATOM 12770 N LEU D 470 -39.541 -36.574 -95.119 1.00 56.67 N +ATOM 12771 CA LEU D 470 -39.159 -37.953 -94.853 1.00 53.93 C +ATOM 12772 C LEU D 470 -37.660 -38.122 -94.623 1.00 56.23 C +ATOM 12773 O LEU D 470 -37.251 -39.166 -94.104 1.00 54.48 O +ATOM 12774 CB LEU D 470 -39.619 -38.833 -96.018 1.00 49.04 C +ATOM 12775 CG LEU D 470 -40.478 -40.064 -95.717 1.00 47.26 C +ATOM 12776 CD1 LEU D 470 -39.640 -41.179 -95.141 1.00 52.75 C +ATOM 12777 CD2 LEU D 470 -41.578 -39.711 -94.762 1.00 52.42 C +ATOM 12778 N VAL D 471 -36.848 -37.115 -94.969 1.00 55.25 N +ATOM 12779 CA VAL D 471 -35.390 -37.278 -94.900 1.00 50.08 C +ATOM 12780 C VAL D 471 -34.919 -37.695 -93.516 1.00 51.18 C +ATOM 12781 O VAL D 471 -33.961 -38.477 -93.425 1.00 53.45 O +ATOM 12782 CB VAL D 471 -34.694 -36.012 -95.424 1.00 48.78 C +ATOM 12783 CG1 VAL D 471 -33.187 -36.158 -95.346 1.00 51.27 C +ATOM 12784 CG2 VAL D 471 -35.127 -35.733 -96.851 1.00 47.96 C +ATOM 12785 N PRO D 472 -35.491 -37.207 -92.408 1.00 55.09 N +ATOM 12786 CA PRO D 472 -35.167 -37.807 -91.100 1.00 57.33 C +ATOM 12787 C PRO D 472 -35.280 -39.325 -91.074 1.00 53.43 C +ATOM 12788 O PRO D 472 -34.468 -39.995 -90.423 1.00 47.57 O +ATOM 12789 CB PRO D 472 -36.194 -37.161 -90.158 1.00 55.63 C +ATOM 12790 CG PRO D 472 -36.652 -35.908 -90.842 1.00 57.19 C +ATOM 12791 CD PRO D 472 -36.123 -35.885 -92.252 1.00 57.91 C +ATOM 12792 N LEU D 473 -36.274 -39.885 -91.763 1.00 52.98 N +ATOM 12793 CA LEU D 473 -36.473 -41.328 -91.740 1.00 50.67 C +ATOM 12794 C LEU D 473 -35.561 -42.031 -92.738 1.00 53.64 C +ATOM 12795 O LEU D 473 -35.041 -43.113 -92.446 1.00 59.47 O +ATOM 12796 CB LEU D 473 -37.941 -41.657 -92.013 1.00 47.31 C +ATOM 12797 CG LEU D 473 -38.364 -43.121 -91.920 1.00 41.87 C +ATOM 12798 CD1 LEU D 473 -37.932 -43.674 -90.580 1.00 45.19 C +ATOM 12799 CD2 LEU D 473 -39.871 -43.265 -92.083 1.00 38.00 C +ATOM 12800 N THR D 474 -35.345 -41.434 -93.914 1.00 49.35 N +ATOM 12801 CA THR D 474 -34.465 -42.052 -94.901 1.00 50.81 C +ATOM 12802 C THR D 474 -33.001 -42.019 -94.474 1.00 56.17 C +ATOM 12803 O THR D 474 -32.197 -42.787 -95.012 1.00 62.42 O +ATOM 12804 CB THR D 474 -34.606 -41.374 -96.266 1.00 51.11 C +ATOM 12805 OG1 THR D 474 -34.186 -40.009 -96.176 1.00 58.80 O +ATOM 12806 CG2 THR D 474 -36.047 -41.424 -96.742 1.00 48.77 C +ATOM 12807 N GLN D 475 -32.630 -41.135 -93.550 1.00 56.29 N +ATOM 12808 CA GLN D 475 -31.264 -41.085 -93.046 1.00 57.74 C +ATOM 12809 C GLN D 475 -31.078 -41.857 -91.754 1.00 55.24 C +ATOM 12810 O GLN D 475 -29.981 -42.360 -91.498 1.00 62.32 O +ATOM 12811 CB GLN D 475 -30.830 -39.633 -92.823 1.00 64.19 C +ATOM 12812 CG GLN D 475 -30.733 -38.826 -94.103 1.00 69.72 C +ATOM 12813 CD GLN D 475 -30.358 -37.380 -93.858 1.00 70.68 C +ATOM 12814 OE1 GLN D 475 -30.479 -36.873 -92.742 1.00 69.19 O +ATOM 12815 NE2 GLN D 475 -29.905 -36.704 -94.908 1.00 75.60 N +ATOM 12816 N CYS D 476 -32.121 -41.961 -90.937 1.00 55.02 N +ATOM 12817 CA CYS D 476 -32.015 -42.689 -89.681 1.00 65.09 C +ATOM 12818 C CYS D 476 -32.395 -44.151 -89.827 1.00 62.88 C +ATOM 12819 O CYS D 476 -31.736 -45.023 -89.251 1.00 66.65 O +ATOM 12820 CB CYS D 476 -32.887 -42.025 -88.615 1.00 66.97 C +ATOM 12821 SG CYS D 476 -32.108 -40.589 -87.865 1.00 81.71 S +ATOM 12822 N CYS D 477 -33.460 -44.424 -90.569 1.00 55.15 N +ATOM 12823 CA CYS D 477 -33.882 -45.782 -90.887 1.00 56.82 C +ATOM 12824 C CYS D 477 -34.065 -46.625 -89.630 1.00 50.82 C +ATOM 12825 O CYS D 477 -33.382 -47.624 -89.402 1.00 55.60 O +ATOM 12826 CB CYS D 477 -32.904 -46.438 -91.852 1.00 60.22 C +ATOM 12827 SG CYS D 477 -33.324 -46.060 -93.542 1.00 80.89 S +ATOM 12828 N ARG D 478 -35.019 -46.200 -88.814 1.00 46.85 N +ATOM 12829 CA ARG D 478 -35.442 -46.993 -87.675 1.00 57.07 C +ATOM 12830 C ARG D 478 -36.767 -46.439 -87.188 1.00 53.89 C +ATOM 12831 O ARG D 478 -36.994 -45.234 -87.255 1.00 59.25 O +ATOM 12832 CB ARG D 478 -34.393 -47.001 -86.558 1.00 58.24 C +ATOM 12833 CG ARG D 478 -33.979 -45.652 -86.055 1.00 61.54 C +ATOM 12834 CD ARG D 478 -33.088 -45.782 -84.831 1.00 76.08 C +ATOM 12835 NE ARG D 478 -32.328 -47.031 -84.808 1.00 88.44 N +ATOM 12836 CZ ARG D 478 -32.602 -48.055 -84.006 1.00 88.14 C +ATOM 12837 NH1 ARG D 478 -33.624 -47.974 -83.167 1.00 78.17 N +ATOM 12838 NH2 ARG D 478 -31.861 -49.157 -84.041 1.00 81.70 N +ATOM 12839 N VAL D 479 -37.657 -47.332 -86.752 1.00 52.86 N +ATOM 12840 CA VAL D 479 -39.005 -46.958 -86.352 1.00 50.93 C +ATOM 12841 C VAL D 479 -39.445 -47.841 -85.195 1.00 57.97 C +ATOM 12842 O VAL D 479 -38.874 -48.902 -84.934 1.00 62.17 O +ATOM 12843 CB VAL D 479 -40.021 -47.074 -87.510 1.00 48.91 C +ATOM 12844 CG1 VAL D 479 -39.886 -45.897 -88.456 1.00 48.34 C +ATOM 12845 CG2 VAL D 479 -39.835 -48.388 -88.243 1.00 56.17 C +ATOM 12846 N LYS D 480 -40.502 -47.402 -84.526 1.00 62.30 N +ATOM 12847 CA LYS D 480 -41.055 -48.144 -83.408 1.00 69.88 C +ATOM 12848 C LYS D 480 -41.928 -49.271 -83.943 1.00 67.86 C +ATOM 12849 O LYS D 480 -42.781 -49.047 -84.810 1.00 65.54 O +ATOM 12850 CB LYS D 480 -41.853 -47.202 -82.504 1.00 68.10 C +ATOM 12851 CG LYS D 480 -42.293 -47.788 -81.170 1.00 67.82 C +ATOM 12852 CD LYS D 480 -43.094 -46.759 -80.388 1.00 64.61 C +ATOM 12853 CE LYS D 480 -42.277 -45.496 -80.164 1.00 57.07 C +ATOM 12854 NZ LYS D 480 -43.079 -44.419 -79.525 1.00 52.87 N +ATOM 12855 N ARG D 481 -41.683 -50.494 -83.459 1.00 61.85 N +ATOM 12856 CA ARG D 481 -42.428 -51.640 -83.973 1.00 62.68 C +ATOM 12857 C ARG D 481 -43.929 -51.431 -83.824 1.00 60.78 C +ATOM 12858 O ARG D 481 -44.704 -51.790 -84.721 1.00 55.09 O +ATOM 12859 CB ARG D 481 -41.990 -52.922 -83.264 1.00 68.00 C +ATOM 12860 CG ARG D 481 -42.738 -54.159 -83.754 1.00 76.12 C +ATOM 12861 CD ARG D 481 -42.257 -55.453 -83.107 1.00 74.85 C +ATOM 12862 NE ARG D 481 -43.025 -56.595 -83.598 1.00 73.50 N +ATOM 12863 CZ ARG D 481 -42.781 -57.862 -83.281 1.00 75.33 C +ATOM 12864 NH1 ARG D 481 -43.540 -58.829 -83.782 1.00 72.65 N +ATOM 12865 NH2 ARG D 481 -41.769 -58.164 -82.480 1.00 80.24 N +ATOM 12866 N SER D 482 -44.349 -50.798 -82.723 1.00 57.28 N +ATOM 12867 CA SER D 482 -45.757 -50.466 -82.525 1.00 58.08 C +ATOM 12868 C SER D 482 -46.311 -49.683 -83.700 1.00 54.92 C +ATOM 12869 O SER D 482 -47.430 -49.936 -84.159 1.00 52.16 O +ATOM 12870 CB SER D 482 -45.926 -49.650 -81.245 1.00 59.94 C +ATOM 12871 OG SER D 482 -47.262 -49.206 -81.088 1.00 67.52 O +ATOM 12872 N THR D 483 -45.539 -48.729 -84.200 1.00 60.19 N +ATOM 12873 CA THR D 483 -46.024 -47.912 -85.297 1.00 64.51 C +ATOM 12874 C THR D 483 -45.911 -48.636 -86.632 1.00 59.97 C +ATOM 12875 O THR D 483 -46.789 -48.484 -87.488 1.00 55.04 O +ATOM 12876 CB THR D 483 -45.257 -46.588 -85.328 1.00 67.68 C +ATOM 12877 OG1 THR D 483 -43.924 -46.813 -85.806 1.00 63.05 O +ATOM 12878 CG2 THR D 483 -45.188 -46.000 -83.926 1.00 60.03 C +ATOM 12879 N TYR D 484 -44.874 -49.457 -86.813 1.00 56.33 N +ATOM 12880 CA TYR D 484 -44.717 -50.157 -88.083 1.00 59.97 C +ATOM 12881 C TYR D 484 -45.898 -51.085 -88.335 1.00 60.89 C +ATOM 12882 O TYR D 484 -46.530 -51.033 -89.398 1.00 55.32 O +ATOM 12883 CB TYR D 484 -43.403 -50.938 -88.103 1.00 55.23 C +ATOM 12884 CG TYR D 484 -42.951 -51.328 -89.496 1.00 51.52 C +ATOM 12885 CD1 TYR D 484 -43.638 -50.888 -90.620 1.00 52.60 C +ATOM 12886 CD2 TYR D 484 -41.848 -52.146 -89.688 1.00 51.47 C +ATOM 12887 CE1 TYR D 484 -43.234 -51.242 -91.892 1.00 53.74 C +ATOM 12888 CE2 TYR D 484 -41.436 -52.506 -90.959 1.00 51.58 C +ATOM 12889 CZ TYR D 484 -42.134 -52.048 -92.056 1.00 51.32 C +ATOM 12890 OH TYR D 484 -41.739 -52.392 -93.327 1.00 50.71 O +ATOM 12891 N LEU D 485 -46.233 -51.919 -87.351 1.00 61.03 N +ATOM 12892 CA LEU D 485 -47.370 -52.812 -87.523 1.00 59.02 C +ATOM 12893 C LEU D 485 -48.660 -52.032 -87.729 1.00 64.34 C +ATOM 12894 O LEU D 485 -49.516 -52.452 -88.516 1.00 70.12 O +ATOM 12895 CB LEU D 485 -47.491 -53.736 -86.315 1.00 55.64 C +ATOM 12896 CG LEU D 485 -46.283 -54.624 -86.040 1.00 61.99 C +ATOM 12897 CD1 LEU D 485 -46.559 -55.474 -84.819 1.00 70.93 C +ATOM 12898 CD2 LEU D 485 -45.965 -55.488 -87.255 1.00 70.98 C +ATOM 12899 N ARG D 486 -48.802 -50.878 -87.071 1.00 58.04 N +ATOM 12900 CA ARG D 486 -49.975 -50.045 -87.315 1.00 52.89 C +ATOM 12901 C ARG D 486 -49.980 -49.529 -88.746 1.00 56.45 C +ATOM 12902 O ARG D 486 -50.972 -49.688 -89.465 1.00 59.44 O +ATOM 12903 CB ARG D 486 -50.038 -48.889 -86.318 1.00 54.20 C +ATOM 12904 CG ARG D 486 -50.489 -49.287 -84.914 1.00 59.17 C +ATOM 12905 CD ARG D 486 -50.902 -48.061 -84.110 1.00 55.48 C +ATOM 12906 NE ARG D 486 -50.005 -47.794 -82.988 1.00 59.30 N +ATOM 12907 CZ ARG D 486 -50.183 -48.261 -81.757 1.00 66.93 C +ATOM 12908 NH1 ARG D 486 -51.228 -49.028 -81.478 1.00 68.51 N +ATOM 12909 NH2 ARG D 486 -49.313 -47.960 -80.803 1.00 70.33 N +ATOM 12910 N LEU D 487 -48.873 -48.918 -89.182 1.00 56.42 N +ATOM 12911 CA LEU D 487 -48.827 -48.346 -90.526 1.00 56.98 C +ATOM 12912 C LEU D 487 -49.141 -49.390 -91.590 1.00 60.52 C +ATOM 12913 O LEU D 487 -49.842 -49.099 -92.567 1.00 58.49 O +ATOM 12914 CB LEU D 487 -47.458 -47.724 -90.790 1.00 53.34 C +ATOM 12915 CG LEU D 487 -47.092 -46.525 -89.922 1.00 55.35 C +ATOM 12916 CD1 LEU D 487 -45.745 -45.961 -90.347 1.00 54.29 C +ATOM 12917 CD2 LEU D 487 -48.188 -45.472 -89.992 1.00 51.47 C +ATOM 12918 N GLN D 488 -48.648 -50.618 -91.412 1.00 63.98 N +ATOM 12919 CA GLN D 488 -49.041 -51.702 -92.308 1.00 63.50 C +ATOM 12920 C GLN D 488 -50.531 -51.976 -92.200 1.00 62.19 C +ATOM 12921 O GLN D 488 -51.226 -52.109 -93.213 1.00 65.40 O +ATOM 12922 CB GLN D 488 -48.245 -52.964 -91.993 1.00 60.85 C +ATOM 12923 CG GLN D 488 -46.786 -52.877 -92.348 1.00 59.25 C +ATOM 12924 CD GLN D 488 -45.995 -54.010 -91.749 1.00 63.99 C +ATOM 12925 OE1 GLN D 488 -46.345 -54.530 -90.688 1.00 67.66 O +ATOM 12926 NE2 GLN D 488 -44.926 -54.411 -92.427 1.00 68.82 N +ATOM 12927 N LEU D 489 -51.041 -52.045 -90.970 1.00 57.11 N +ATOM 12928 CA LEU D 489 -52.458 -52.307 -90.767 1.00 60.28 C +ATOM 12929 C LEU D 489 -53.321 -51.204 -91.362 1.00 61.88 C +ATOM 12930 O LEU D 489 -54.416 -51.475 -91.869 1.00 62.35 O +ATOM 12931 CB LEU D 489 -52.741 -52.456 -89.277 1.00 56.93 C +ATOM 12932 CG LEU D 489 -54.164 -52.863 -88.928 1.00 60.91 C +ATOM 12933 CD1 LEU D 489 -54.381 -54.321 -89.273 1.00 65.95 C +ATOM 12934 CD2 LEU D 489 -54.416 -52.607 -87.461 1.00 70.61 C +ATOM 12935 N LEU D 490 -52.847 -49.963 -91.319 1.00 59.14 N +ATOM 12936 CA LEU D 490 -53.586 -48.842 -91.880 1.00 55.07 C +ATOM 12937 C LEU D 490 -53.476 -48.770 -93.395 1.00 54.60 C +ATOM 12938 O LEU D 490 -53.905 -47.773 -93.982 1.00 58.67 O +ATOM 12939 CB LEU D 490 -53.104 -47.524 -91.261 1.00 53.68 C +ATOM 12940 CG LEU D 490 -53.704 -47.029 -89.935 1.00 45.03 C +ATOM 12941 CD1 LEU D 490 -55.124 -47.527 -89.754 1.00 51.74 C +ATOM 12942 CD2 LEU D 490 -52.850 -47.389 -88.735 1.00 50.15 C +ATOM 12943 N ALA D 491 -52.920 -49.795 -94.040 1.00 56.29 N +ATOM 12944 CA ALA D 491 -52.796 -49.830 -95.490 1.00 54.29 C +ATOM 12945 C ALA D 491 -53.678 -50.884 -96.140 1.00 55.15 C +ATOM 12946 O ALA D 491 -53.675 -50.997 -97.369 1.00 52.64 O +ATOM 12947 CB ALA D 491 -51.335 -50.067 -95.888 1.00 52.17 C +ATOM 12948 N LYS D 492 -54.429 -51.655 -95.353 1.00 61.91 N +ATOM 12949 CA LYS D 492 -55.302 -52.700 -95.876 1.00 64.25 C +ATOM 12950 C LYS D 492 -56.663 -52.116 -96.233 1.00 67.84 C +ATOM 12951 O LYS D 492 -57.182 -51.251 -95.522 1.00 70.22 O +ATOM 12952 CB LYS D 492 -55.474 -53.824 -94.849 1.00 58.80 C +ATOM 12953 CG LYS D 492 -54.402 -54.907 -94.894 1.00 57.76 C +ATOM 12954 CD LYS D 492 -53.033 -54.346 -94.536 1.00 60.57 C +ATOM 12955 CE LYS D 492 -51.903 -55.263 -94.983 1.00 80.16 C +ATOM 12956 NZ LYS D 492 -50.565 -54.601 -94.891 1.00 72.88 N +ATOM 12957 N GLU D 493 -57.256 -52.620 -97.321 1.00 64.36 N +ATOM 12958 CA GLU D 493 -58.502 -52.037 -97.815 1.00 66.84 C +ATOM 12959 C GLU D 493 -59.624 -52.130 -96.788 1.00 69.21 C +ATOM 12960 O GLU D 493 -60.532 -51.291 -96.788 1.00 67.29 O +ATOM 12961 CB GLU D 493 -58.921 -52.709 -99.123 1.00 64.57 C +ATOM 12962 CG GLU D 493 -58.943 -51.767-100.321 1.00 74.96 C +ATOM 12963 CD GLU D 493 -60.093 -50.769-100.272 1.00 84.86 C +ATOM 12964 OE1 GLU D 493 -61.088 -51.029 -99.558 1.00 84.65 O +ATOM 12965 OE2 GLU D 493 -60.001 -49.722-100.953 1.00 81.97 O +ATOM 12966 N GLU D 494 -59.591 -53.144 -95.918 1.00 72.22 N +ATOM 12967 CA GLU D 494 -60.606 -53.263 -94.874 1.00 78.45 C +ATOM 12968 C GLU D 494 -60.466 -52.178 -93.812 1.00 73.37 C +ATOM 12969 O GLU D 494 -61.453 -51.824 -93.155 1.00 68.06 O +ATOM 12970 CB GLU D 494 -60.563 -54.653 -94.236 1.00 75.78 C +ATOM 12971 CG GLU D 494 -59.181 -55.203 -93.942 1.00 72.45 C +ATOM 12972 CD GLU D 494 -58.645 -56.042 -95.092 1.00 81.97 C +ATOM 12973 OE1 GLU D 494 -58.502 -55.499 -96.209 1.00 85.82 O +ATOM 12974 OE2 GLU D 494 -58.399 -57.252 -94.888 1.00 81.60 O +ATOM 12975 N TYR D 495 -59.258 -51.664 -93.607 1.00 71.65 N +ATOM 12976 CA TYR D 495 -59.058 -50.592 -92.641 1.00 71.18 C +ATOM 12977 C TYR D 495 -58.736 -49.280 -93.347 1.00 74.81 C +ATOM 12978 O TYR D 495 -59.616 -48.429 -93.511 1.00 81.28 O +ATOM 12979 CB TYR D 495 -57.953 -50.969 -91.657 1.00 66.26 C +ATOM 12980 CG TYR D 495 -58.366 -52.046 -90.685 1.00 67.99 C +ATOM 12981 CD1 TYR D 495 -59.684 -52.482 -90.617 1.00 72.89 C +ATOM 12982 CD2 TYR D 495 -57.448 -52.606 -89.815 1.00 65.65 C +ATOM 12983 CE1 TYR D 495 -60.071 -53.462 -89.717 1.00 77.76 C +ATOM 12984 CE2 TYR D 495 -57.823 -53.584 -88.909 1.00 71.69 C +ATOM 12985 CZ TYR D 495 -59.134 -54.008 -88.863 1.00 73.19 C +ATOM 12986 OH TYR D 495 -59.500 -54.980 -87.960 1.00 67.26 O +ATOM 12987 N LYS D 496 -57.480 -49.113 -93.756 1.00 71.66 N +ATOM 12988 CA LYS D 496 -57.015 -47.981 -94.554 1.00 71.60 C +ATOM 12989 C LYS D 496 -57.232 -46.632 -93.874 1.00 64.65 C +ATOM 12990 O LYS D 496 -57.846 -46.549 -92.807 1.00 61.02 O +ATOM 12991 CB LYS D 496 -57.666 -48.011 -95.947 1.00 70.96 C +ATOM 12992 CG LYS D 496 -58.888 -47.131 -96.173 1.00 66.86 C +ATOM 12993 CD LYS D 496 -59.417 -47.349 -97.590 1.00 74.39 C +ATOM 12994 CE LYS D 496 -58.292 -47.228 -98.625 1.00 71.47 C +ATOM 12995 NZ LYS D 496 -58.732 -47.536-100.017 1.00 70.95 N +ATOM 12996 N LEU D 497 -56.722 -45.569 -94.490 1.00 67.83 N +ATOM 12997 CA LEU D 497 -56.715 -44.240 -93.895 1.00 64.71 C +ATOM 12998 C LEU D 497 -57.886 -43.372 -94.328 1.00 66.38 C +ATOM 12999 O LEU D 497 -58.500 -42.720 -93.480 1.00 72.12 O +ATOM 13000 CB LEU D 497 -55.400 -43.530 -94.232 1.00 59.37 C +ATOM 13001 CG LEU D 497 -54.462 -43.243 -93.063 1.00 46.69 C +ATOM 13002 CD1 LEU D 497 -54.849 -41.957 -92.392 1.00 50.78 C +ATOM 13003 CD2 LEU D 497 -54.543 -44.365 -92.073 1.00 51.54 C +ATOM 13004 N SER D 498 -58.219 -43.350 -95.620 1.00 62.53 N +ATOM 13005 CA SER D 498 -59.261 -42.443 -96.095 1.00 69.50 C +ATOM 13006 C SER D 498 -60.598 -42.733 -95.421 1.00 75.10 C +ATOM 13007 O SER D 498 -61.213 -41.841 -94.823 1.00 71.14 O +ATOM 13008 CB SER D 498 -59.390 -42.537 -97.619 1.00 73.42 C +ATOM 13009 OG SER D 498 -59.780 -43.834 -98.037 1.00 78.34 O +ATOM 13010 N SER D 499 -61.043 -43.989 -95.470 1.00 72.66 N +ATOM 13011 CA SER D 499 -62.320 -44.340 -94.861 1.00 72.67 C +ATOM 13012 C SER D 499 -62.279 -44.199 -93.341 1.00 76.35 C +ATOM 13013 O SER D 499 -63.307 -43.904 -92.720 1.00 79.73 O +ATOM 13014 CB SER D 499 -62.715 -45.754 -95.283 1.00 73.73 C +ATOM 13015 OG SER D 499 -61.781 -46.703 -94.801 1.00 79.42 O +ATOM 13016 N LEU D 500 -61.107 -44.385 -92.728 1.00 71.39 N +ATOM 13017 CA LEU D 500 -60.973 -44.150 -91.293 1.00 69.15 C +ATOM 13018 C LEU D 500 -60.886 -42.669 -90.963 1.00 62.68 C +ATOM 13019 O LEU D 500 -61.295 -42.256 -89.873 1.00 67.47 O +ATOM 13020 CB LEU D 500 -59.743 -44.869 -90.735 1.00 65.87 C +ATOM 13021 CG LEU D 500 -59.948 -46.321 -90.307 1.00 67.29 C +ATOM 13022 CD1 LEU D 500 -58.654 -46.929 -89.809 1.00 64.14 C +ATOM 13023 CD2 LEU D 500 -61.005 -46.389 -89.221 1.00 71.34 C +ATOM 13024 N MET D 501 -60.331 -41.863 -91.864 1.00 56.64 N +ATOM 13025 CA MET D 501 -60.179 -40.448 -91.562 1.00 60.39 C +ATOM 13026 C MET D 501 -61.470 -39.681 -91.824 1.00 61.15 C +ATOM 13027 O MET D 501 -61.852 -38.823 -91.024 1.00 64.49 O +ATOM 13028 CB MET D 501 -59.011 -39.875 -92.368 1.00 66.59 C +ATOM 13029 CG MET D 501 -58.474 -38.513 -91.927 1.00 58.10 C +ATOM 13030 SD MET D 501 -57.658 -38.471 -90.314 1.00 47.99 S +ATOM 13031 CE MET D 501 -57.042 -40.143 -90.159 1.00 55.31 C +ATOM 13032 N GLU D 502 -62.173 -39.979 -92.919 1.00 58.08 N +ATOM 13033 CA GLU D 502 -63.446 -39.302 -93.140 1.00 61.84 C +ATOM 13034 C GLU D 502 -64.512 -39.735 -92.140 1.00 64.51 C +ATOM 13035 O GLU D 502 -65.510 -39.026 -91.976 1.00 59.82 O +ATOM 13036 CB GLU D 502 -63.946 -39.530 -94.565 1.00 68.98 C +ATOM 13037 CG GLU D 502 -64.480 -40.919 -94.824 1.00 81.72 C +ATOM 13038 CD GLU D 502 -65.076 -41.060 -96.212 1.00 84.57 C +ATOM 13039 OE1 GLU D 502 -65.214 -40.034 -96.916 1.00 68.18 O +ATOM 13040 OE2 GLU D 502 -65.408 -42.202 -96.595 1.00 97.61 O +ATOM 13041 N GLU D 503 -64.333 -40.882 -91.478 1.00 67.30 N +ATOM 13042 CA GLU D 503 -65.279 -41.306 -90.450 1.00 65.51 C +ATOM 13043 C GLU D 503 -65.247 -40.367 -89.246 1.00 62.04 C +ATOM 13044 O GLU D 503 -66.255 -39.735 -88.911 1.00 61.68 O +ATOM 13045 CB GLU D 503 -64.981 -42.746 -90.023 1.00 68.14 C +ATOM 13046 CG GLU D 503 -65.723 -43.182 -88.760 1.00 85.99 C +ATOM 13047 CD GLU D 503 -66.935 -44.061 -89.041 1.00 94.25 C +ATOM 13048 OE1 GLU D 503 -66.756 -45.158 -89.617 1.00 96.40 O +ATOM 13049 OE2 GLU D 503 -68.065 -43.656 -88.680 1.00 84.82 O +ATOM 13050 N SER D 504 -64.091 -40.259 -88.582 1.00 60.98 N +ATOM 13051 CA SER D 504 -64.017 -39.444 -87.371 1.00 65.70 C +ATOM 13052 C SER D 504 -64.122 -37.956 -87.690 1.00 64.95 C +ATOM 13053 O SER D 504 -64.705 -37.193 -86.912 1.00 71.36 O +ATOM 13054 CB SER D 504 -62.729 -39.740 -86.604 1.00 60.62 C +ATOM 13055 OG SER D 504 -61.588 -39.515 -87.406 1.00 60.13 O +ATOM 13056 N LEU D 505 -63.541 -37.521 -88.813 1.00 61.38 N +ATOM 13057 CA LEU D 505 -63.683 -36.132 -89.244 1.00 65.30 C +ATOM 13058 C LEU D 505 -65.123 -35.778 -89.587 1.00 69.57 C +ATOM 13059 O LEU D 505 -65.456 -34.590 -89.681 1.00 67.86 O +ATOM 13060 CB LEU D 505 -62.797 -35.856 -90.456 1.00 67.05 C +ATOM 13061 CG LEU D 505 -61.295 -35.806 -90.182 1.00 71.22 C +ATOM 13062 CD1 LEU D 505 -60.538 -35.494 -91.462 1.00 71.30 C +ATOM 13063 CD2 LEU D 505 -60.965 -34.798 -89.089 1.00 71.64 C +ATOM 13064 N LEU D 506 -65.977 -36.779 -89.805 1.00 66.44 N +ATOM 13065 CA LEU D 506 -67.387 -36.517 -90.040 1.00 59.24 C +ATOM 13066 C LEU D 506 -68.092 -36.068 -88.768 1.00 62.04 C +ATOM 13067 O LEU D 506 -69.183 -35.494 -88.843 1.00 63.02 O +ATOM 13068 CB LEU D 506 -68.054 -37.774 -90.600 1.00 56.63 C +ATOM 13069 CG LEU D 506 -69.433 -37.661 -91.247 1.00 62.77 C +ATOM 13070 CD1 LEU D 506 -69.352 -36.901 -92.559 1.00 64.95 C +ATOM 13071 CD2 LEU D 506 -70.033 -39.041 -91.456 1.00 62.53 C +ATOM 13072 N GLN D 507 -67.475 -36.289 -87.608 1.00 64.49 N +ATOM 13073 CA GLN D 507 -68.044 -35.883 -86.325 1.00 65.45 C +ATOM 13074 C GLN D 507 -67.414 -34.561 -85.885 1.00 64.14 C +ATOM 13075 O GLN D 507 -66.615 -34.488 -84.955 1.00 69.05 O +ATOM 13076 CB GLN D 507 -67.840 -36.986 -85.285 1.00 63.49 C +ATOM 13077 CG GLN D 507 -68.375 -36.678 -83.886 1.00 79.93 C +ATOM 13078 CD GLN D 507 -69.762 -36.059 -83.897 1.00 96.23 C +ATOM 13079 OE1 GLN D 507 -70.669 -36.547 -84.576 1.00103.85 O +ATOM 13080 NE2 GLN D 507 -69.934 -34.978 -83.140 1.00 86.06 N +ATOM 13081 N ASP D 508 -67.778 -33.500 -86.604 1.00 62.25 N +ATOM 13082 CA ASP D 508 -67.339 -32.154 -86.259 1.00 65.44 C +ATOM 13083 C ASP D 508 -68.240 -31.160 -86.973 1.00 66.95 C +ATOM 13084 O ASP D 508 -68.526 -31.324 -88.162 1.00 65.79 O +ATOM 13085 CB ASP D 508 -65.873 -31.914 -86.646 1.00 64.37 C +ATOM 13086 CG ASP D 508 -65.272 -30.688 -85.961 1.00 66.12 C +ATOM 13087 OD1 ASP D 508 -65.935 -30.085 -85.087 1.00 64.15 O +ATOM 13088 OD2 ASP D 508 -64.128 -30.322 -86.304 1.00 63.74 O +ATOM 13089 N ARG D 509 -68.637 -30.100 -86.264 1.00 68.40 N +ATOM 13090 CA ARG D 509 -69.537 -29.108 -86.843 1.00 67.22 C +ATOM 13091 C ARG D 509 -68.817 -28.294 -87.910 1.00 59.94 C +ATOM 13092 O ARG D 509 -68.971 -27.072 -87.988 1.00 63.96 O +ATOM 13093 CB ARG D 509 -70.113 -28.188 -85.763 1.00 63.29 C +ATOM 13094 CG ARG D 509 -71.385 -27.453 -86.187 1.00 61.83 C +ATOM 13095 CD ARG D 509 -71.467 -26.079 -85.543 1.00 74.75 C +ATOM 13096 NE ARG D 509 -72.371 -25.177 -86.253 1.00 75.36 N +ATOM 13097 CZ ARG D 509 -73.680 -25.096 -86.036 1.00 88.33 C +ATOM 13098 NH1 ARG D 509 -74.418 -24.242 -86.734 1.00 82.90 N +ATOM 13099 NH2 ARG D 509 -74.253 -25.866 -85.121 1.00 96.22 N +ATOM 13100 N LEU D 510 -68.010 -28.962 -88.723 1.00 52.33 N +ATOM 13101 CA LEU D 510 -67.294 -28.290 -89.789 1.00 58.37 C +ATOM 13102 C LEU D 510 -67.159 -29.133 -91.048 1.00 61.12 C +ATOM 13103 O LEU D 510 -66.575 -28.652 -92.024 1.00 63.28 O +ATOM 13104 CB LEU D 510 -65.907 -27.840 -89.311 1.00 58.20 C +ATOM 13105 CG LEU D 510 -65.670 -26.332 -89.449 1.00 56.22 C +ATOM 13106 CD1 LEU D 510 -66.496 -25.774 -90.600 1.00 57.78 C +ATOM 13107 CD2 LEU D 510 -65.988 -25.592 -88.170 1.00 49.84 C +ATOM 13108 N VAL D 511 -67.658 -30.366 -91.055 1.00 62.79 N +ATOM 13109 CA VAL D 511 -67.520 -31.274 -92.193 1.00 64.13 C +ATOM 13110 C VAL D 511 -68.059 -30.589 -93.449 1.00 58.76 C +ATOM 13111 O VAL D 511 -69.084 -29.890 -93.388 1.00 54.92 O +ATOM 13112 CB VAL D 511 -68.226 -32.614 -91.900 1.00 61.26 C +ATOM 13113 CG1 VAL D 511 -69.754 -32.493 -92.000 1.00 53.58 C +ATOM 13114 CG2 VAL D 511 -67.686 -33.742 -92.776 1.00 56.34 C +ATOM 13115 N PRO D 512 -67.386 -30.724 -94.606 1.00 53.78 N +ATOM 13116 CA PRO D 512 -66.126 -31.447 -94.813 1.00 53.51 C +ATOM 13117 C PRO D 512 -64.892 -30.662 -94.385 1.00 56.26 C +ATOM 13118 O PRO D 512 -64.579 -29.649 -95.007 1.00 54.31 O +ATOM 13119 CB PRO D 512 -66.097 -31.681 -96.330 1.00 50.36 C +ATOM 13120 CG PRO D 512 -67.427 -31.198 -96.852 1.00 52.57 C +ATOM 13121 CD PRO D 512 -67.901 -30.186 -95.871 1.00 50.80 C +ATOM 13122 N VAL D 513 -64.203 -31.130 -93.340 1.00 57.02 N +ATOM 13123 CA VAL D 513 -62.987 -30.452 -92.901 1.00 57.37 C +ATOM 13124 C VAL D 513 -61.854 -30.675 -93.896 1.00 61.77 C +ATOM 13125 O VAL D 513 -60.986 -29.808 -94.065 1.00 60.11 O +ATOM 13126 CB VAL D 513 -62.597 -30.916 -91.485 1.00 53.76 C +ATOM 13127 CG1 VAL D 513 -63.744 -30.676 -90.521 1.00 62.66 C +ATOM 13128 CG2 VAL D 513 -62.211 -32.378 -91.490 1.00 51.66 C +ATOM 13129 N LEU D 514 -61.842 -31.824 -94.570 1.00 62.64 N +ATOM 13130 CA LEU D 514 -60.851 -32.150 -95.588 1.00 56.00 C +ATOM 13131 C LEU D 514 -61.572 -32.464 -96.886 1.00 57.57 C +ATOM 13132 O LEU D 514 -62.375 -33.402 -96.942 1.00 55.22 O +ATOM 13133 CB LEU D 514 -59.990 -33.341 -95.168 1.00 48.20 C +ATOM 13134 CG LEU D 514 -58.930 -33.079 -94.108 1.00 45.41 C +ATOM 13135 CD1 LEU D 514 -58.097 -34.319 -93.881 1.00 41.33 C +ATOM 13136 CD2 LEU D 514 -58.060 -31.926 -94.559 1.00 48.67 C +ATOM 13137 N ILE D 515 -61.260 -31.702 -97.935 1.00 59.84 N +ATOM 13138 CA ILE D 515 -61.742 -32.053 -99.260 1.00 61.40 C +ATOM 13139 C ILE D 515 -61.219 -33.449 -99.605 1.00 62.72 C +ATOM 13140 O ILE D 515 -60.201 -33.908 -99.069 1.00 59.34 O +ATOM 13141 CB ILE D 515 -61.317 -30.997-100.298 1.00 61.03 C +ATOM 13142 CG1 ILE D 515 -62.123 -31.139-101.595 1.00 66.25 C +ATOM 13143 CG2 ILE D 515 -59.817 -31.058-100.567 1.00 57.87 C +ATOM 13144 CD1 ILE D 515 -63.606 -30.857-101.428 1.00 63.82 C +ATOM 13145 N LYS D 516 -61.959 -34.155-100.458 1.00 63.62 N +ATOM 13146 CA LYS D 516 -61.658 -35.563-100.705 1.00 65.17 C +ATOM 13147 C LYS D 516 -60.240 -35.823-101.214 1.00 60.39 C +ATOM 13148 O LYS D 516 -59.663 -36.853-100.822 1.00 60.03 O +ATOM 13149 CB LYS D 516 -62.700 -36.152-101.667 1.00 64.81 C +ATOM 13150 CG LYS D 516 -62.697 -37.674-101.702 1.00 67.18 C +ATOM 13151 CD LYS D 516 -63.907 -38.231-102.432 1.00 70.70 C +ATOM 13152 CE LYS D 516 -63.973 -39.748-102.293 1.00 73.97 C +ATOM 13153 NZ LYS D 516 -65.210 -40.321-102.899 1.00 75.11 N +ATOM 13154 N PRO D 517 -59.629 -34.981-102.063 1.00 58.56 N +ATOM 13155 CA PRO D 517 -58.240 -35.257-102.475 1.00 55.03 C +ATOM 13156 C PRO D 517 -57.272 -35.452-101.321 1.00 56.25 C +ATOM 13157 O PRO D 517 -56.375 -36.298-101.413 1.00 55.72 O +ATOM 13158 CB PRO D 517 -57.882 -34.016-103.303 1.00 52.21 C +ATOM 13159 CG PRO D 517 -59.163 -33.598-103.895 1.00 56.13 C +ATOM 13160 CD PRO D 517 -60.211 -33.879-102.856 1.00 56.98 C +ATOM 13161 N HIS D 518 -57.438 -34.704-100.227 1.00 60.68 N +ATOM 13162 CA HIS D 518 -56.537 -34.855 -99.087 1.00 61.84 C +ATOM 13163 C HIS D 518 -56.773 -36.176 -98.367 1.00 63.32 C +ATOM 13164 O HIS D 518 -55.815 -36.850 -97.967 1.00 61.25 O +ATOM 13165 CB HIS D 518 -56.702 -33.675 -98.127 1.00 51.65 C +ATOM 13166 CG HIS D 518 -56.125 -32.391 -98.641 1.00 53.55 C +ATOM 13167 ND1 HIS D 518 -56.907 -31.316 -99.006 1.00 55.25 N +ATOM 13168 CD2 HIS D 518 -54.842 -32.006 -98.838 1.00 53.01 C +ATOM 13169 CE1 HIS D 518 -56.133 -30.326 -99.414 1.00 51.06 C +ATOM 13170 NE2 HIS D 518 -54.875 -30.718 -99.320 1.00 54.20 N +ATOM 13171 N LEU D 519 -58.038 -36.566 -98.191 1.00 65.94 N +ATOM 13172 CA LEU D 519 -58.329 -37.847 -97.555 1.00 66.20 C +ATOM 13173 C LEU D 519 -57.734 -38.995 -98.354 1.00 66.31 C +ATOM 13174 O LEU D 519 -57.254 -39.980 -97.783 1.00 66.97 O +ATOM 13175 CB LEU D 519 -59.839 -38.039 -97.411 1.00 67.36 C +ATOM 13176 CG LEU D 519 -60.585 -37.123 -96.444 1.00 70.45 C +ATOM 13177 CD1 LEU D 519 -62.081 -37.196 -96.701 1.00 77.85 C +ATOM 13178 CD2 LEU D 519 -60.270 -37.518 -95.009 1.00 65.52 C +ATOM 13179 N GLU D 520 -57.753 -38.877 -99.680 1.00 66.58 N +ATOM 13180 CA GLU D 520 -57.214 -39.921-100.537 1.00 70.59 C +ATOM 13181 C GLU D 520 -55.693 -39.851-100.603 1.00 67.48 C +ATOM 13182 O GLU D 520 -55.019 -40.888-100.619 1.00 62.66 O +ATOM 13183 CB GLU D 520 -57.839 -39.797-101.926 1.00 74.82 C +ATOM 13184 CG GLU D 520 -57.599 -40.964-102.852 1.00 87.39 C +ATOM 13185 CD GLU D 520 -58.199 -40.725-104.222 1.00 89.49 C +ATOM 13186 OE1 GLU D 520 -59.041 -39.809-104.346 1.00 69.19 O +ATOM 13187 OE2 GLU D 520 -57.837 -41.454-105.170 1.00118.91 O +ATOM 13188 N ALA D 521 -55.137 -38.636-100.602 1.00 67.26 N +ATOM 13189 CA ALA D 521 -53.687 -38.487-100.579 1.00 65.53 C +ATOM 13190 C ALA D 521 -53.085 -39.089 -99.319 1.00 63.19 C +ATOM 13191 O ALA D 521 -51.920 -39.499 -99.326 1.00 66.71 O +ATOM 13192 CB ALA D 521 -53.309 -37.011-100.696 1.00 59.29 C +ATOM 13193 N LEU D 522 -53.865 -39.165 -98.237 1.00 63.63 N +ATOM 13194 CA LEU D 522 -53.363 -39.730 -96.989 1.00 66.58 C +ATOM 13195 C LEU D 522 -52.837 -41.148 -97.187 1.00 72.88 C +ATOM 13196 O LEU D 522 -51.783 -41.506 -96.648 1.00 73.89 O +ATOM 13197 CB LEU D 522 -54.469 -39.706 -95.933 1.00 64.33 C +ATOM 13198 CG LEU D 522 -54.149 -39.080 -94.577 1.00 54.97 C +ATOM 13199 CD1 LEU D 522 -53.188 -37.926 -94.734 1.00 49.59 C +ATOM 13200 CD2 LEU D 522 -55.435 -38.606 -93.920 1.00 55.13 C +ATOM 13201 N ASP D 523 -53.548 -41.968 -97.972 1.00 75.74 N +ATOM 13202 CA ASP D 523 -53.071 -43.320 -98.257 1.00 75.15 C +ATOM 13203 C ASP D 523 -51.841 -43.307 -99.155 1.00 70.96 C +ATOM 13204 O ASP D 523 -50.976 -44.184 -99.036 1.00 66.91 O +ATOM 13205 CB ASP D 523 -54.183 -44.157 -98.896 1.00 76.41 C +ATOM 13206 CG ASP D 523 -55.374 -44.365 -97.971 1.00 72.40 C +ATOM 13207 OD1 ASP D 523 -56.262 -43.487 -97.924 1.00 68.96 O +ATOM 13208 OD2 ASP D 523 -55.413 -45.408 -97.283 1.00 72.92 O +ATOM 13209 N ARG D 524 -51.739 -42.322-100.047 1.00 67.24 N +ATOM 13210 CA ARG D 524 -50.588 -42.256-100.939 1.00 67.37 C +ATOM 13211 C ARG D 524 -49.317 -41.926-100.167 1.00 67.98 C +ATOM 13212 O ARG D 524 -48.271 -42.546-100.390 1.00 69.27 O +ATOM 13213 CB ARG D 524 -50.854 -41.232-102.041 1.00 66.95 C +ATOM 13214 CG ARG D 524 -49.696 -40.994-102.984 1.00 62.61 C +ATOM 13215 CD ARG D 524 -50.074 -39.932-103.987 1.00 62.72 C +ATOM 13216 NE ARG D 524 -50.565 -38.728-103.327 1.00 59.70 N +ATOM 13217 CZ ARG D 524 -50.907 -37.615-103.964 1.00 66.87 C +ATOM 13218 NH1 ARG D 524 -50.813 -37.547-105.286 1.00 71.88 N +ATOM 13219 NH2 ARG D 524 -51.341 -36.568-103.278 1.00 65.69 N +ATOM 13220 N ARG D 525 -49.391 -40.970 -99.237 1.00 73.00 N +ATOM 13221 CA ARG D 525 -48.238 -40.677 -98.393 1.00 66.07 C +ATOM 13222 C ARG D 525 -47.924 -41.842 -97.461 1.00 65.65 C +ATOM 13223 O ARG D 525 -46.762 -42.036 -97.086 1.00 67.62 O +ATOM 13224 CB ARG D 525 -48.473 -39.393 -97.592 1.00 60.91 C +ATOM 13225 CG ARG D 525 -48.359 -38.111 -98.413 1.00 56.62 C +ATOM 13226 CD ARG D 525 -49.698 -37.397 -98.505 1.00 60.59 C +ATOM 13227 NE ARG D 525 -49.653 -36.213 -99.359 1.00 60.59 N +ATOM 13228 CZ ARG D 525 -49.626 -34.965 -98.904 1.00 60.25 C +ATOM 13229 NH1 ARG D 525 -49.638 -34.740 -97.599 1.00 71.50 N +ATOM 13230 NH2 ARG D 525 -49.590 -33.944 -99.749 1.00 57.85 N +ATOM 13231 N LEU D 526 -48.935 -42.621 -97.072 1.00 61.85 N +ATOM 13232 CA LEU D 526 -48.688 -43.752 -96.184 1.00 66.26 C +ATOM 13233 C LEU D 526 -47.896 -44.852 -96.883 1.00 70.22 C +ATOM 13234 O LEU D 526 -46.993 -45.449 -96.283 1.00 68.61 O +ATOM 13235 CB LEU D 526 -50.007 -44.305 -95.652 1.00 62.86 C +ATOM 13236 CG LEU D 526 -49.916 -45.622 -94.879 1.00 54.88 C +ATOM 13237 CD1 LEU D 526 -48.972 -45.528 -93.687 1.00 47.55 C +ATOM 13238 CD2 LEU D 526 -51.303 -46.012 -94.432 1.00 57.40 C +ATOM 13239 N ARG D 527 -48.237 -45.160 -98.137 1.00 70.63 N +ATOM 13240 CA ARG D 527 -47.534 -46.233 -98.835 1.00 76.85 C +ATOM 13241 C ARG D 527 -46.093 -45.861 -99.176 1.00 69.44 C +ATOM 13242 O ARG D 527 -45.259 -46.758 -99.343 1.00 67.28 O +ATOM 13243 CB ARG D 527 -48.298 -46.650-100.096 1.00 75.83 C +ATOM 13244 CG ARG D 527 -48.360 -45.612-101.189 1.00 78.32 C +ATOM 13245 CD ARG D 527 -48.242 -46.281-102.550 1.00 87.68 C +ATOM 13246 NE ARG D 527 -48.575 -45.378-103.645 1.00 90.34 N +ATOM 13247 CZ ARG D 527 -49.804 -45.196-104.113 1.00 82.06 C +ATOM 13248 NH1 ARG D 527 -50.822 -45.858-103.576 1.00 77.22 N +ATOM 13249 NH2 ARG D 527 -50.014 -44.349-105.114 1.00 75.17 N +ATOM 13250 N LEU D 528 -45.782 -44.568 -99.296 1.00 57.53 N +ATOM 13251 CA LEU D 528 -44.393 -44.163 -99.487 1.00 56.98 C +ATOM 13252 C LEU D 528 -43.598 -44.303 -98.195 1.00 61.35 C +ATOM 13253 O LEU D 528 -42.421 -44.679 -98.222 1.00 59.44 O +ATOM 13254 CB LEU D 528 -44.326 -42.730-100.005 1.00 56.73 C +ATOM 13255 CG LEU D 528 -45.027 -42.501-101.341 1.00 60.16 C +ATOM 13256 CD1 LEU D 528 -44.789 -41.079-101.843 1.00 63.29 C +ATOM 13257 CD2 LEU D 528 -44.571 -43.529-102.364 1.00 61.75 C +ATOM 13258 N VAL D 529 -44.217 -43.978 -97.058 1.00 60.59 N +ATOM 13259 CA VAL D 529 -43.578 -44.215 -95.766 1.00 60.22 C +ATOM 13260 C VAL D 529 -43.334 -45.704 -95.568 1.00 65.50 C +ATOM 13261 O VAL D 529 -42.235 -46.134 -95.194 1.00 62.86 O +ATOM 13262 CB VAL D 529 -44.443 -43.642 -94.631 1.00 49.43 C +ATOM 13263 CG1 VAL D 529 -43.910 -44.085 -93.273 1.00 50.64 C +ATOM 13264 CG2 VAL D 529 -44.497 -42.141 -94.727 1.00 58.30 C +ATOM 13265 N LEU D 530 -44.351 -46.517 -95.863 1.00 65.23 N +ATOM 13266 CA LEU D 530 -44.212 -47.958 -95.713 1.00 62.40 C +ATOM 13267 C LEU D 530 -43.120 -48.500 -96.625 1.00 60.21 C +ATOM 13268 O LEU D 530 -42.364 -49.394 -96.224 1.00 55.73 O +ATOM 13269 CB LEU D 530 -45.562 -48.626 -95.987 1.00 54.81 C +ATOM 13270 CG LEU D 530 -45.958 -49.788 -95.072 1.00 60.08 C +ATOM 13271 CD1 LEU D 530 -45.759 -49.416 -93.616 1.00 62.62 C +ATOM 13272 CD2 LEU D 530 -47.406 -50.181 -95.316 1.00 60.00 C +ATOM 13273 N LYS D 531 -42.973 -47.920 -97.820 1.00 60.72 N +ATOM 13274 CA LYS D 531 -41.955 -48.382 -98.758 1.00 63.99 C +ATOM 13275 C LYS D 531 -40.565 -47.946 -98.316 1.00 62.16 C +ATOM 13276 O LYS D 531 -39.589 -48.678 -98.509 1.00 67.91 O +ATOM 13277 CB LYS D 531 -42.260 -47.860-100.165 1.00 69.36 C +ATOM 13278 CG LYS D 531 -41.354 -48.392-101.284 1.00 65.21 C +ATOM 13279 CD LYS D 531 -41.518 -49.895-101.492 1.00 77.86 C +ATOM 13280 CE LYS D 531 -42.844 -50.230-102.176 1.00 88.59 C +ATOM 13281 NZ LYS D 531 -43.030 -51.695-102.402 1.00 84.80 N +ATOM 13282 N VAL D 532 -40.452 -46.749 -97.737 1.00 57.24 N +ATOM 13283 CA VAL D 532 -39.162 -46.306 -97.217 1.00 58.41 C +ATOM 13284 C VAL D 532 -38.700 -47.222 -96.093 1.00 58.12 C +ATOM 13285 O VAL D 532 -37.497 -47.461 -95.920 1.00 57.65 O +ATOM 13286 CB VAL D 532 -39.245 -44.835 -96.766 1.00 56.76 C +ATOM 13287 CG1 VAL D 532 -38.007 -44.449 -95.969 1.00 56.52 C +ATOM 13288 CG2 VAL D 532 -39.405 -43.930 -97.971 1.00 50.53 C +ATOM 13289 N LEU D 533 -39.641 -47.746 -95.309 1.00 53.62 N +ATOM 13290 CA LEU D 533 -39.283 -48.723 -94.291 1.00 58.63 C +ATOM 13291 C LEU D 533 -38.824 -50.037 -94.921 1.00 68.87 C +ATOM 13292 O LEU D 533 -37.907 -50.689 -94.409 1.00 68.60 O +ATOM 13293 CB LEU D 533 -40.471 -48.940 -93.356 1.00 57.30 C +ATOM 13294 CG LEU D 533 -40.955 -47.672 -92.641 1.00 52.01 C +ATOM 13295 CD1 LEU D 533 -42.109 -47.972 -91.709 1.00 51.42 C +ATOM 13296 CD2 LEU D 533 -39.826 -47.006 -91.877 1.00 45.03 C +ATOM 13297 N SER D 534 -39.433 -50.425 -96.047 1.00 73.52 N +ATOM 13298 CA SER D 534 -39.086 -51.675 -96.723 1.00 72.69 C +ATOM 13299 C SER D 534 -37.772 -51.560 -97.491 1.00 74.69 C +ATOM 13300 O SER D 534 -36.924 -52.458 -97.423 1.00 73.73 O +ATOM 13301 CB SER D 534 -40.218 -52.083 -97.668 1.00 63.36 C +ATOM 13302 OG SER D 534 -41.447 -52.171 -96.968 1.00 67.89 O +ATOM 13303 N ASP D 535 -37.598 -50.471 -98.247 1.00 75.74 N +ATOM 13304 CA ASP D 535 -36.365 -50.263 -98.996 1.00 73.21 C +ATOM 13305 C ASP D 535 -35.160 -50.130 -98.083 1.00 72.58 C +ATOM 13306 O ASP D 535 -34.025 -50.292 -98.541 1.00 79.75 O +ATOM 13307 CB ASP D 535 -36.475 -49.019 -99.875 1.00 67.60 C +ATOM 13308 CG ASP D 535 -37.524 -49.164-100.954 1.00 83.34 C +ATOM 13309 OD1 ASP D 535 -37.724 -50.299-101.435 1.00 87.52 O +ATOM 13310 OD2 ASP D 535 -38.143 -48.145-101.325 1.00 95.56 O +ATOM 13311 N CYS D 536 -35.375 -49.826 -96.808 1.00 69.91 N +ATOM 13312 CA CYS D 536 -34.257 -49.670 -95.896 1.00 84.27 C +ATOM 13313 C CYS D 536 -34.038 -50.882 -95.005 1.00 87.58 C +ATOM 13314 O CYS D 536 -32.890 -51.188 -94.664 1.00 83.97 O +ATOM 13315 CB CYS D 536 -34.459 -48.430 -95.024 1.00 81.36 C +ATOM 13316 SG CYS D 536 -32.884 -47.787 -94.488 1.00129.54 S +ATOM 13317 N VAL D 537 -35.108 -51.592 -94.637 1.00 85.55 N +ATOM 13318 CA VAL D 537 -34.950 -52.804 -93.846 1.00 79.26 C +ATOM 13319 C VAL D 537 -34.246 -53.902 -94.635 1.00 79.07 C +ATOM 13320 O VAL D 537 -33.742 -54.862 -94.041 1.00 73.84 O +ATOM 13321 CB VAL D 537 -36.319 -53.278 -93.324 1.00 73.32 C +ATOM 13322 CG1 VAL D 537 -37.108 -53.988 -94.419 1.00 61.20 C +ATOM 13323 CG2 VAL D 537 -36.133 -54.167 -92.115 1.00 73.82 C +ATOM 13324 N GLU D 538 -34.194 -53.787 -95.962 1.00 83.25 N +ATOM 13325 CA GLU D 538 -33.398 -54.692 -96.778 1.00 80.17 C +ATOM 13326 C GLU D 538 -31.927 -54.297 -96.821 1.00 84.34 C +ATOM 13327 O GLU D 538 -31.105 -55.091 -97.292 1.00 85.34 O +ATOM 13328 CB GLU D 538 -33.959 -54.756 -98.197 1.00 77.52 C +ATOM 13329 CG GLU D 538 -33.700 -53.514 -99.019 1.00 81.69 C +ATOM 13330 CD GLU D 538 -34.189 -53.651-100.445 1.00 92.57 C +ATOM 13331 OE1 GLU D 538 -33.357 -53.541-101.372 1.00102.87 O +ATOM 13332 OE2 GLU D 538 -35.401 -53.901-100.634 1.00 87.71 O +ATOM 13333 N LYS D 539 -31.580 -53.087 -96.368 1.00 79.52 N +ATOM 13334 CA LYS D 539 -30.193 -52.646 -96.329 1.00 77.60 C +ATOM 13335 C LYS D 539 -29.607 -52.573 -94.927 1.00 75.01 C +ATOM 13336 O LYS D 539 -28.381 -52.508 -94.796 1.00 76.05 O +ATOM 13337 CB LYS D 539 -30.039 -51.276 -97.008 1.00 79.08 C +ATOM 13338 CG LYS D 539 -30.297 -51.306 -98.511 1.00 90.19 C +ATOM 13339 CD LYS D 539 -30.048 -49.946 -99.149 1.00 95.34 C +ATOM 13340 CE LYS D 539 -30.309 -49.976-100.650 1.00 90.34 C +ATOM 13341 NZ LYS D 539 -30.115 -48.629-101.262 1.00 94.12 N +ATOM 13342 N ASP D 540 -30.439 -52.587 -93.883 1.00 72.94 N +ATOM 13343 CA ASP D 540 -29.958 -52.644 -92.509 1.00 70.60 C +ATOM 13344 C ASP D 540 -30.513 -53.815 -91.711 1.00 69.45 C +ATOM 13345 O ASP D 540 -29.985 -54.105 -90.629 1.00 60.72 O +ATOM 13346 CB ASP D 540 -30.290 -51.343 -91.762 1.00 76.96 C +ATOM 13347 CG ASP D 540 -29.382 -50.198 -92.153 1.00 84.35 C +ATOM 13348 OD1 ASP D 540 -28.199 -50.466 -92.453 1.00 92.71 O +ATOM 13349 OD2 ASP D 540 -29.841 -49.033 -92.141 1.00 73.19 O +ATOM 13350 N GLY D 541 -31.546 -54.488 -92.200 1.00 72.26 N +ATOM 13351 CA GLY D 541 -32.105 -55.642 -91.528 1.00 72.00 C +ATOM 13352 C GLY D 541 -33.054 -55.267 -90.403 1.00 70.71 C +ATOM 13353 O GLY D 541 -32.992 -54.186 -89.822 1.00 79.18 O +ATOM 13354 N PHE D 542 -33.947 -56.200 -90.085 1.00 61.35 N +ATOM 13355 CA PHE D 542 -34.825 -56.026 -88.939 1.00 68.08 C +ATOM 13356 C PHE D 542 -34.003 -56.037 -87.649 1.00 74.09 C +ATOM 13357 O PHE D 542 -32.780 -56.205 -87.656 1.00 76.75 O +ATOM 13358 CB PHE D 542 -35.892 -57.117 -88.916 1.00 73.02 C +ATOM 13359 CG PHE D 542 -36.905 -56.996 -90.015 1.00 89.39 C +ATOM 13360 CD1 PHE D 542 -36.632 -57.499 -91.283 1.00103.71 C +ATOM 13361 CD2 PHE D 542 -38.135 -56.400 -89.783 1.00 75.23 C +ATOM 13362 CE1 PHE D 542 -37.562 -57.393 -92.308 1.00 94.90 C +ATOM 13363 CE2 PHE D 542 -39.071 -56.292 -90.804 1.00 94.34 C +ATOM 13364 CZ PHE D 542 -38.781 -56.790 -92.068 1.00 92.64 C +ATOM 13365 N SER D 543 -34.692 -55.805 -86.527 1.00 76.19 N +ATOM 13366 CA SER D 543 -34.102 -55.747 -85.186 1.00 83.79 C +ATOM 13367 C SER D 543 -33.095 -54.607 -85.039 1.00 82.73 C +ATOM 13368 O SER D 543 -32.949 -54.039 -83.949 1.00 71.91 O +ATOM 13369 CB SER D 543 -33.453 -57.085 -84.818 1.00 87.19 C +ATOM 13370 OG SER D 543 -34.415 -58.128 -84.778 1.00 76.39 O +ATOM 13371 N ALA D 544 -32.403 -54.266 -86.126 1.00 87.56 N +ATOM 13372 CA ALA D 544 -31.553 -53.088 -86.206 1.00 92.19 C +ATOM 13373 C ALA D 544 -32.252 -51.934 -86.910 1.00 82.05 C +ATOM 13374 O ALA D 544 -31.693 -50.834 -86.991 1.00 78.08 O +ATOM 13375 CB ALA D 544 -30.243 -53.423 -86.932 1.00 82.03 C +ATOM 13376 N VAL D 545 -33.460 -52.164 -87.417 1.00 69.55 N +ATOM 13377 CA VAL D 545 -34.320 -51.105 -87.914 1.00 60.02 C +ATOM 13378 C VAL D 545 -35.565 -50.959 -87.053 1.00 65.65 C +ATOM 13379 O VAL D 545 -35.998 -49.842 -86.766 1.00 71.18 O +ATOM 13380 CB VAL D 545 -34.698 -51.337 -89.393 1.00 58.53 C +ATOM 13381 CG1 VAL D 545 -35.850 -50.443 -89.788 1.00 60.11 C +ATOM 13382 CG2 VAL D 545 -33.516 -51.045 -90.284 1.00 68.69 C +ATOM 13383 N VAL D 546 -36.141 -52.069 -86.607 1.00 71.51 N +ATOM 13384 CA VAL D 546 -37.294 -52.050 -85.717 1.00 71.52 C +ATOM 13385 C VAL D 546 -36.827 -52.475 -84.329 1.00 72.71 C +ATOM 13386 O VAL D 546 -36.176 -53.516 -84.174 1.00 77.35 O +ATOM 13387 CB VAL D 546 -38.426 -52.947 -86.248 1.00 75.91 C +ATOM 13388 CG1 VAL D 546 -39.129 -52.250 -87.406 1.00 61.63 C +ATOM 13389 CG2 VAL D 546 -37.883 -54.302 -86.714 1.00 79.08 C +ATOM 13390 N GLU D 547 -37.111 -51.650 -83.329 1.00 71.88 N +ATOM 13391 CA GLU D 547 -36.784 -51.975 -81.948 1.00 77.22 C +ATOM 13392 C GLU D 547 -38.045 -52.476 -81.260 1.00 78.95 C +ATOM 13393 O GLU D 547 -39.061 -51.772 -81.231 1.00 75.44 O +ATOM 13394 CB GLU D 547 -36.204 -50.768 -81.216 1.00 73.56 C +ATOM 13395 CG GLU D 547 -34.736 -50.535 -81.525 1.00 87.93 C +ATOM 13396 CD GLU D 547 -34.078 -49.614 -80.524 1.00100.25 C +ATOM 13397 OE1 GLU D 547 -34.789 -48.751 -79.970 1.00103.50 O +ATOM 13398 OE2 GLU D 547 -32.852 -49.740 -80.305 1.00106.03 O +ATOM 13399 N ASN D 548 -37.990 -53.703 -80.743 1.00 78.75 N +ATOM 13400 CA ASN D 548 -39.148 -54.278 -80.073 1.00 75.75 C +ATOM 13401 C ASN D 548 -39.550 -53.438 -78.870 1.00 71.39 C +ATOM 13402 O ASN D 548 -38.764 -53.242 -77.937 1.00 70.67 O +ATOM 13403 CB ASN D 548 -38.852 -55.713 -79.647 1.00 72.36 C +ATOM 13404 CG ASN D 548 -40.093 -56.586 -79.646 1.00 70.91 C +ATOM 13405 OD1 ASN D 548 -41.222 -56.089 -79.707 1.00 65.85 O +ATOM 13406 ND2 ASN D 548 -39.889 -57.895 -79.590 1.00 78.90 N +ATOM 13407 N ASP D 549 -40.793 -52.971 -78.886 1.00 67.91 N +ATOM 13408 CA ASP D 549 -41.400 -52.281 -77.762 1.00 67.59 C +ATOM 13409 C ASP D 549 -42.604 -53.020 -77.202 1.00 67.62 C +ATOM 13410 O ASP D 549 -42.908 -52.858 -76.014 1.00 62.44 O +ATOM 13411 CB ASP D 549 -41.795 -50.842 -78.140 1.00 59.79 C +ATOM 13412 CG ASP D 549 -42.712 -50.774 -79.335 1.00 55.94 C +ATOM 13413 OD1 ASP D 549 -42.451 -51.462 -80.345 1.00 56.38 O +ATOM 13414 OD2 ASP D 549 -43.696 -50.017 -79.258 1.00 55.30 O +ATOM 13415 N LEU D 550 -43.276 -53.840 -78.015 1.00 65.42 N +ATOM 13416 CA LEU D 550 -44.504 -54.541 -77.662 1.00 63.36 C +ATOM 13417 C LEU D 550 -44.286 -55.715 -76.713 1.00 68.64 C +ATOM 13418 O LEU D 550 -45.256 -56.413 -76.397 1.00 66.11 O +ATOM 13419 CB LEU D 550 -45.196 -55.044 -78.939 1.00 60.03 C +ATOM 13420 CG LEU D 550 -46.304 -54.198 -79.583 1.00 58.05 C +ATOM 13421 CD1 LEU D 550 -46.072 -52.718 -79.351 1.00 63.46 C +ATOM 13422 CD2 LEU D 550 -46.442 -54.487 -81.078 1.00 50.09 C +ATOM 13423 N ASP D 551 -43.063 -55.938 -76.232 1.00 72.03 N +ATOM 13424 CA ASP D 551 -42.831 -56.986 -75.244 1.00 67.79 C +ATOM 13425 C ASP D 551 -43.596 -56.690 -73.963 1.00 62.76 C +ATOM 13426 O ASP D 551 -43.061 -56.060 -73.046 1.00 58.39 O +ATOM 13427 CB ASP D 551 -41.342 -57.133 -74.949 1.00 65.32 C +ATOM 13428 CG ASP D 551 -40.574 -57.639 -76.144 1.00 77.96 C +ATOM 13429 OD1 ASP D 551 -41.206 -58.249 -77.036 1.00 84.52 O +ATOM 13430 OD2 ASP D 551 -39.347 -57.418 -76.198 1.00 77.07 O +ATOM 13431 N GLY D 552 -44.847 -57.139 -73.904 1.00 62.09 N +ATOM 13432 CA GLY D 552 -45.702 -56.930 -72.752 1.00 51.25 C +ATOM 13433 C GLY D 552 -47.164 -56.873 -73.147 1.00 48.35 C +ATOM 13434 O GLY D 552 -47.953 -57.740 -72.773 1.00 51.30 O +TER 13435 GLY D 552 +HETATM13436 PG ATP A 701 -63.590 -17.845 -48.220 1.00 84.39 P +HETATM13437 O1G ATP A 701 -64.752 -18.587 -48.837 1.00 81.20 O +HETATM13438 O2G ATP A 701 -63.584 -17.796 -46.711 1.00 80.33 O +HETATM13439 O3G ATP A 701 -62.252 -18.208 -48.822 1.00 76.61 O +HETATM13440 PB ATP A 701 -62.842 -15.131 -48.613 1.00 93.11 P +HETATM13441 O1B ATP A 701 -61.449 -15.703 -48.722 1.00 87.07 O +HETATM13442 O2B ATP A 701 -63.169 -14.155 -47.506 1.00 75.15 O +HETATM13443 O3B ATP A 701 -63.915 -16.328 -48.660 1.00 91.56 O +HETATM13444 PA ATP A 701 -62.110 -13.656 -50.833 1.00 99.03 P +HETATM13445 O1A ATP A 701 -61.990 -14.324 -52.182 1.00101.88 O +HETATM13446 O2A ATP A 701 -60.881 -13.498 -49.966 1.00 85.03 O +HETATM13447 O3A ATP A 701 -63.243 -14.410 -49.987 1.00 79.12 O +HETATM13448 O5' ATP A 701 -62.813 -12.217 -50.982 1.00 73.52 O +HETATM13449 C5' ATP A 701 -62.304 -11.121 -50.229 1.00 74.72 C +HETATM13450 C4' ATP A 701 -61.974 -9.941 -51.133 1.00 73.33 C +HETATM13451 O4' ATP A 701 -62.143 -8.747 -50.368 1.00 68.96 O +HETATM13452 C3' ATP A 701 -60.529 -9.967 -51.626 1.00 65.43 C +HETATM13453 O3' ATP A 701 -60.433 -10.252 -53.028 1.00 53.27 O +HETATM13454 C2' ATP A 701 -59.990 -8.577 -51.358 1.00 65.72 C +HETATM13455 O2' ATP A 701 -59.710 -7.926 -52.601 1.00 71.04 O +HETATM13456 C1' ATP A 701 -61.092 -7.820 -50.638 1.00 67.31 C +HETATM13457 N9 ATP A 701 -60.599 -7.249 -49.360 1.00 57.41 N +HETATM13458 C8 ATP A 701 -60.900 -7.701 -48.131 1.00 50.96 C +HETATM13459 N7 ATP A 701 -60.297 -6.947 -47.177 1.00 49.12 N +HETATM13460 C5 ATP A 701 -59.595 -5.988 -47.805 1.00 51.61 C +HETATM13461 C6 ATP A 701 -58.725 -4.857 -47.401 1.00 58.23 C +HETATM13462 N6 ATP A 701 -58.477 -4.596 -46.097 1.00 52.25 N +HETATM13463 N1 ATP A 701 -58.187 -4.088 -48.376 1.00 66.11 N +HETATM13464 C2 ATP A 701 -58.422 -4.336 -49.680 1.00 66.69 C +HETATM13465 N3 ATP A 701 -59.197 -5.346 -50.115 1.00 66.53 N +HETATM13466 C4 ATP A 701 -59.802 -6.190 -49.244 1.00 57.66 C +HETATM13467 PG ATP B 701 -34.768 13.088-117.524 1.00 75.24 P +HETATM13468 O1G ATP B 701 -34.668 13.025-119.030 1.00 69.81 O +HETATM13469 O2G ATP B 701 -34.280 14.367-116.879 1.00 58.38 O +HETATM13470 O3G ATP B 701 -34.268 11.836-116.844 1.00 78.18 O +HETATM13471 PB ATP B 701 -37.326 11.876-117.180 1.00 74.16 P +HETATM13472 O1B ATP B 701 -38.498 12.045-118.110 1.00 68.91 O +HETATM13473 O2B ATP B 701 -36.536 10.587-117.223 1.00 64.75 O +HETATM13474 O3B ATP B 701 -36.354 13.157-117.246 1.00 77.50 O +HETATM13475 PA ATP B 701 -38.666 10.998-114.936 1.00 82.59 P +HETATM13476 O1A ATP B 701 -38.595 9.759-115.792 1.00 75.64 O +HETATM13477 O2A ATP B 701 -38.138 11.001-113.521 1.00 88.28 O +HETATM13478 O3A ATP B 701 -37.928 12.172-115.726 1.00 69.61 O +HETATM13479 O5' ATP B 701 -40.190 11.507-114.980 1.00 64.31 O +HETATM13480 C5' ATP B 701 -41.170 10.681-115.603 1.00 62.18 C +HETATM13481 C4' ATP B 701 -42.344 10.452-114.663 1.00 61.08 C +HETATM13482 O4' ATP B 701 -43.533 10.365-115.444 1.00 61.39 O +HETATM13483 C3' ATP B 701 -42.196 9.151-113.886 1.00 58.94 C +HETATM13484 O3' ATP B 701 -42.199 9.406-112.477 1.00 54.69 O +HETATM13485 C2' ATP B 701 -43.404 8.314-114.249 1.00 60.97 C +HETATM13486 O2' ATP B 701 -44.097 7.923-113.061 1.00 69.04 O +HETATM13487 C1' ATP B 701 -44.297 9.220-115.078 1.00 59.58 C +HETATM13488 N9 ATP B 701 -44.742 8.541-116.313 1.00 54.38 N +HETATM13489 C8 ATP B 701 -44.233 8.727-117.544 1.00 49.61 C +HETATM13490 N7 ATP B 701 -44.878 7.957-118.454 1.00 45.20 N +HETATM13491 C5 ATP B 701 -45.824 7.264-117.795 1.00 49.94 C +HETATM13492 C6 ATP B 701 -46.863 6.269-118.146 1.00 57.59 C +HETATM13493 N6 ATP B 701 -47.028 5.843-119.423 1.00 55.38 N +HETATM13494 N1 ATP B 701 -47.644 5.798-117.146 1.00 63.74 N +HETATM13495 C2 ATP B 701 -47.496 6.208-115.871 1.00 61.29 C +HETATM13496 N3 ATP B 701 -46.576 7.107-115.483 1.00 58.09 N +HETATM13497 C4 ATP B 701 -45.730 7.658-116.383 1.00 53.07 C +CONECT 902 1804 +CONECT 916 1837 +CONECT 1762 1892 +CONECT 1804 902 +CONECT 1837 916 +CONECT 1892 1762 +CONECT 2271 2878 +CONECT 2878 2271 +CONECT 2884 3360 +CONECT 3360 2884 +CONECT 4967 5096 +CONECT 5009 5045 +CONECT 5045 5009 +CONECT 5096 4967 +CONECT 5501 6109 +CONECT 6109 5501 +CONECT 6115 6604 +CONECT 6604 6115 +CONECT 7625 8527 +CONECT 7639 8560 +CONECT 8485 8615 +CONECT 8527 7625 +CONECT 8560 7639 +CONECT 8615 8485 +CONECT 8994 9601 +CONECT 9601 8994 +CONECT 960710083 +CONECT10083 9607 +CONECT1167911808 +CONECT1172111757 +CONECT1175711721 +CONECT1180811679 +CONECT1221312821 +CONECT1282112213 +CONECT1282713316 +CONECT1331612827 +CONECT1343613437134381343913443 +CONECT1343713436 +CONECT1343813436 +CONECT1343913436 +CONECT1344013441134421344313447 +CONECT1344113440 +CONECT1344213440 +CONECT134431343613440 +CONECT1344413445134461344713448 +CONECT1344513444 +CONECT1344613444 +CONECT134471344013444 +CONECT134481344413449 +CONECT134491344813450 +CONECT13450134491345113452 +CONECT134511345013456 +CONECT13452134501345313454 +CONECT1345313452 +CONECT13454134521345513456 +CONECT1345513454 +CONECT13456134511345413457 +CONECT13457134561345813466 +CONECT134581345713459 +CONECT134591345813460 +CONECT13460134591346113466 +CONECT13461134601346213463 +CONECT1346213461 +CONECT134631346113464 +CONECT134641346313465 +CONECT134651346413466 +CONECT13466134571346013465 +CONECT1346713468134691347013474 +CONECT1346813467 +CONECT1346913467 +CONECT1347013467 +CONECT1347113472134731347413478 +CONECT1347213471 +CONECT1347313471 +CONECT134741346713471 +CONECT1347513476134771347813479 +CONECT1347613475 +CONECT1347713475 +CONECT134781347113475 +CONECT134791347513480 +CONECT134801347913481 +CONECT13481134801348213483 +CONECT134821348113487 +CONECT13483134811348413485 +CONECT1348413483 +CONECT13485134831348613487 +CONECT1348613485 +CONECT13487134821348513488 +CONECT13488134871348913497 +CONECT134891348813490 +CONECT134901348913491 +CONECT13491134901349213497 +CONECT13492134911349313494 +CONECT1349313492 +CONECT134941349213495 +CONECT134951349413496 +CONECT134961349513497 +CONECT13497134881349113496 +MASTER 725 0 2 75 50 0 8 613493 4 98 160 +END diff --git a/esm/source/examples/inverse_folding/data/5YH2_mutated_seqs.fasta b/esm/source/examples/inverse_folding/data/5YH2_mutated_seqs.fasta new file mode 100644 index 0000000000000000000000000000000000000000..07285e66e6e58b9d1f82a6472ec596e8a5747c2b --- /dev/null +++ b/esm/source/examples/inverse_folding/data/5YH2_mutated_seqs.fasta @@ -0,0 +1,8 @@ +>mut_1 +SVLQSLFEHPLYRTVLPDLTEEDTLFNLNAEIRLYPKAASESYPNWLRFHIGINRYELYSRHNPVIAALLRDLLSQKISSVGMKSGGTQLKLIMSFQNYGQALFKPMKQTREQETPPDFFYFSDFERHNAEIAAFHLDRILDFRRVPPVAGRLVNMTREIRDVTRDKKLWRTFFVSPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLALAKRKTWRNPWRRSYHKRKKAEWEVDPDYCDEVKQTPPYDRGTRLLDIMDMTIFDFLMGNMDRHHYETFEKFGNDTFIIHLDNGRGFGKHSHDEMSILVPLTQCCRVKRSTYLRLQLLAKEEYKLSSLMEESLLQDRLVPVLIKPHLEALDRRLRLVLKVLSDCVEKDGFSAVVENDLD +>mut_2 +DVLQSLFEHPLYRTVLPDLTEEDTLFNLNAEIRLYPKAASESYPNWLRFHIGINRYELYSRHNPVIAALLRDLLSQKISSVGMKSGGTQLKLIMSFQNYGQALFKPMKQTREQETPPDFFYFSDFERHNAEIAAFHLDRILDFRRVPPVAGRLVNMTREIRDVTRDKKLWRTFFVSPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLALAKRKTWRNPWRRSYHKRKKAEWEVDPDYCDEVKQTPPYDRGTRLLDIMDMTIFDFLMGNMDRHHYETFEKFGNDTFIIHLDNGRGFGKHSHDEMSILVPLTQCCRVKRSTYLRLQLLAKEEYKLSSLMEESLLQDRLVPVLIKPHLEALDRRLRLVLKVLSDCVEKDGFSAVVENDLD +>mut_3 +EVLQSLFEHPLYRTVLPDLTEEDTLFNLNAEIRLYPKAASESYPNWLRFHIGINRYELYSRHNPVIAALLRDLLSQKISSVGMKSGGTQLKLIMSFQNYGQALFKPMKQTREQETPPDFFYFSDFERHNAEIAAFHLDRILDFRRVPPVAGRLVNMTREIRDVTRDKKLWRTFFVSPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLALAKRKTWRNPWRRSYHKRKKAEWEVDPDYCDEVKQTPPYDRGTRLLDIMDMTIFDFLMGNMDRHHYETFEKFGNDTFIIHLDNGRGFGKHSHDEMSILVPLTQCCRVKRSTYLRLQLLAKEEYKLSSLMEESLLQDRLVPVLIKPHLEALDRRLRLVLKVLSDCVEKDGFSAVVENDLD +>mut_4 +VVLQSLFEHPLYRTVLPDLTEEDTLFNLNAEIRLYPKAASESYPNWLRFHIGINRYELYSRHNPVIAALLRDLLSQKISSVGMKSGGTQLKLIMSFQNYGQALFKPMKQTREQETPPDFFYFSDFERHNAEIAAFHLDRILDFRRVPPVAGRLVNMTREIRDVTRDKKLWRTFFVSPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLALAKRKTWRNPWRRSYHKRKKAEWEVDPDYCDEVKQTPPYDRGTRLLDIMDMTIFDFLMGNMDRHHYETFEKFGNDTFIIHLDNGRGFGKHSHDEMSILVPLTQCCRVKRSTYLRLQLLAKEEYKLSSLMEESLLQDRLVPVLIKPHLEALDRRLRLVLKVLSDCVEKDGFSAVVENDLD diff --git a/esm/source/examples/inverse_folding/data/example.json b/esm/source/examples/inverse_folding/data/example.json new file mode 100644 index 0000000000000000000000000000000000000000..c1135d41e439af462daa76425d45c3a94de3894a --- /dev/null +++ b/esm/source/examples/inverse_folding/data/example.json @@ -0,0 +1 @@ +[{"coords": [[[Infinity, Infinity, Infinity], [Infinity, Infinity, Infinity], [Infinity, Infinity, Infinity]], [[99.86399841308594, 52.58100128173828, -5.098999977111816], [98.87999725341797, 51.736000061035156, -5.841000080108643], [97.86199951171875, 51.09700012207031, -4.889999866485596]], [[98.34400177001953, 50.35900115966797, -3.8980000019073486], [97.46099853515625, 49.7239990234375, -2.9230000972747803], [97.66100311279297, 50.36199951171875, -1.5609999895095825]], [[96.5780029296875, 50.7869987487793, -0.9269999861717224], [96.68000030517578, 51.40399932861328, 0.3869999945163727], [95.85700225830078, 50.59600067138672, 1.3669999837875366]], [[96.27400207519531, 50.53300094604492, 2.619999885559082], [95.51699829101562, 49.762001037597656, 3.5959999561309814], [95.36799621582031, 50.46500015258789, 4.919000148773193]], [[94.1240005493164, 50.66699981689453, 5.302999973297119], [93.79000091552734, 51.32899856567383, 6.541999816894531], [93.00399780273438, 50.375, 7.421999931335449]], [[93.4520034790039, 50.18600082397461, 8.656999588012695], [92.74400329589844, 49.303001403808594, 9.571000099182129], [92.20800018310547, 50.15999984741211, 10.678999900817871]], [[90.90299987792969, 50.388999938964844, 10.65999984741211], [90.29000091552734, 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b/esm/source/examples/inverse_folding/notebook.ipynb @@ -0,0 +1,630 @@ +{ + "cells": [ + { + "cell_type": "markdown", + "id": "338533a8", + "metadata": { + "colab_type": "text", + "id": "view-in-github" + }, + "source": [ + "\"Open" + ] + }, + { + "cell_type": "markdown", + "id": "43GQPw7R_ZbY", + "metadata": { + "id": "43GQPw7R_ZbY" + }, + "source": [ + "# Inverse folding with ESM-IF1\n", + "\n", + "The ESM-IF1 inverse folding model is built for predicting protein sequences from their backbone atom coordinates. We provide examples here 1) to sample sequence designs for a given structure and 2) to score sequences for a given structure.\n", + "\n", + "Trained with 12M protein structures predicted by AlphaFold2, the ESM-IF1 model consists of invariant geometric input processing layers followed by a sequence-to-sequence transformer, and achieves 51% native sequence recovery on structurally held-out backbones. The model is also trained with span masking to tolerate missing backbone coordinates and therefore can predict sequences for partially masked structures.\n", + "\n", + "See [GitHub README](https://github.com/facebookresearch/esm/tree/main/examples/inverse_folding) for the complete user guide, and see our [bioRxiv pre-print](https://doi.org/10.1101/2022.04.10.487779) for more details." + ] + }, + { + "cell_type": "markdown", + "id": "8c6TDUVupgNn", + "metadata": { + "id": "8c6TDUVupgNn" + }, + "source": [ + "## Environment setup (colab)\n", + "This step might take up to 10 minutes the first time. \n", + "\n", + "If using a local jupyter environment, instead of the following, we recommend configuring a conda environment upon first use in command line:\n", + "```\n", + "conda create -n inverse python=3.9\n", + "conda activate inverse\n", + "conda install pytorch cudatoolkit=11.3 -c pytorch\n", + "conda install pyg -c pyg -c conda-forge\n", + "conda install pip\n", + "pip install biotite\n", + "pip install git+https://github.com/facebookresearch/esm.git\n", + "```\n", + "\n", + "Afterwards, `conda activate inverse` to activate this environment before starting `jupyter notebook`.\n", + "\n", + "Below is the setup for colab notebooks:\n", + "\n", + "We recommend using GPU runtimes on colab (Menu bar -> Runtime -> Change runtime type -> Hardware accelerator -> GPU)" + ] + }, + { + "cell_type": "code", + "execution_count": 1, + "id": "nLOymXwdwUXo", + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "nLOymXwdwUXo", + "outputId": "894a9af0-d8e9-44f3-e869-830a3e3e90ad" + }, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "\u001b[K |████████████████████████████████| 7.9 MB 16.8 MB/s \n", + "\u001b[K |████████████████████████████████| 3.5 MB 27.7 MB/s \n", + "\u001b[K |████████████████████████████████| 2.5 MB 35.7 MB/s \n", + "\u001b[K |████████████████████████████████| 750 kB 25.8 MB/s \n", + "\u001b[K |████████████████████████████████| 407 kB 30.7 MB/s \n", + "\u001b[?25h Building wheel for torch-geometric (setup.py) ... \u001b[?25l\u001b[?25hdone\n", + " Installing build dependencies ... \u001b[?25l\u001b[?25hdone\n", + " Getting requirements to build wheel ... \u001b[?25l\u001b[?25hdone\n", + " Preparing wheel metadata ... \u001b[?25l\u001b[?25hdone\n", + " Building wheel for fair-esm (PEP 517) ... \u001b[?25l\u001b[?25hdone\n", + "\u001b[K |████████████████████████████████| 31.8 MB 1.2 MB/s \n", + "\u001b[?25h Installing build dependencies ... \u001b[?25l\u001b[?25hdone\n", + " Getting requirements to build wheel ... \u001b[?25l\u001b[?25hdone\n", + " Preparing wheel metadata ... \u001b[?25l\u001b[?25hdone\n", + " Building wheel for biotite (PEP 517) ... \u001b[?25l\u001b[?25hdone\n" + ] + } + ], + "source": [ + "# Colab environment setup\n", + "\n", + "# Install the correct version of Pytorch Geometric.\n", + "import torch\n", + "\n", + "def format_pytorch_version(version):\n", + " return version.split('+')[0]\n", + "\n", + "TORCH_version = torch.__version__\n", + "TORCH = format_pytorch_version(TORCH_version)\n", + "\n", + "def format_cuda_version(version):\n", + " return 'cu' + version.replace('.', '')\n", + "\n", + "CUDA_version = torch.version.cuda\n", + "CUDA = format_cuda_version(CUDA_version)\n", + "\n", + "!pip install -q torch-scatter -f https://data.pyg.org/whl/torch-{TORCH}+{CUDA}.html\n", + "!pip install -q torch-sparse -f https://data.pyg.org/whl/torch-{TORCH}+{CUDA}.html\n", + "!pip install -q torch-cluster -f https://data.pyg.org/whl/torch-{TORCH}+{CUDA}.html\n", + "!pip install -q torch-spline-conv -f https://data.pyg.org/whl/torch-{TORCH}+{CUDA}.html\n", + "!pip install -q torch-geometric\n", + "\n", + "# Install esm\n", + "!pip install -q git+https://github.com/facebookresearch/esm.git\n", + "\n", + "# Install biotite\n", + "!pip install -q biotite" + ] + }, + { + "cell_type": "markdown", + "id": "EhDI4ZIX0Z4w", + "metadata": { + "id": "EhDI4ZIX0Z4w" + }, + "source": [ + "### Verify that pytorch-geometric is correctly installed\n", + "\n", + "If the notebook crashes at the import, there is likely an issue with the version of torch_geometric and torch_sparse being incompatible with the torch version." + ] + }, + { + "cell_type": "code", + "execution_count": 2, + "id": "1-HvBXt1wWPu", + "metadata": { + "id": "1-HvBXt1wWPu" + }, + "outputs": [], + "source": [ + "## Verify that pytorch-geometric is correctly installed\n", + "import torch_geometric\n", + "import torch_sparse\n", + "from torch_geometric.nn import MessagePassing" + ] + }, + { + "cell_type": "markdown", + "id": "18544eee", + "metadata": { + "id": "18544eee" + }, + "source": [ + "## Load model\n", + "This steps takes a few minutes for the model to download.\n", + "\n", + "**UPDATE**: It is important to set the model in eval mode through `model = model.eval()` to disable random dropout for optimal performance." + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "id": "14d8f393", + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "14d8f393", + "outputId": "d84afad9-0cd7-4e96-bedd-2bdae90229b0" + }, + "outputs": [ + { + "name": "stderr", + "output_type": "stream", + "text": [ + "/home/chloehsu/inverse_opensource/esm_public_fork/esm/esm/pretrained.py:172: UserWarning: Regression weights not found, predicting contacts will not produce correct results.\n", + " warnings.warn(\n" + ] + } + ], + "source": [ + "import esm\n", + "model, alphabet = esm.pretrained.esm_if1_gvp4_t16_142M_UR50()\n", + "model = model.eval()" + ] + }, + { + "cell_type": "markdown", + "id": "2a6ed9bb", + "metadata": { + "id": "2a6ed9bb" + }, + "source": [ + "## Load structure from PDB or CIF files\n", + "\n", + "As an example, let's look at Golgi Casein Kinase, the [PDB Molecule of the Month from January 2022](https://pdb101.rcsb.org/motm/265).\n", + "\n", + "Milk is a complex mixture of proteins, fats, and nutrients that provides everything that a growing infant needs. Most of the protein in cow’s milk is casein, whereas human milk has lesser amounts of casein. \n", + "\n", + "The Golgi casein kinase (PDB entry 5YH2) adds phosphates to casein and also to many other types of secreted proteins. It is most active as a complex of two similar types of proteins. Fam20C is the catalytic subunit. It binds to casein and transfers a phosphate from ATP to the protein.\n", + "\n", + "In this example, let's focus on chain C (the catalytic subunit Fam20C).\n", + "\n", + "You may also upload your own CIF or PDB file and specify the chain id." + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "id": "a8hwuySfBDig", + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "a8hwuySfBDig", + "outputId": "fbe2c984-3e79-4b56-981f-cc11441e9d8e" + }, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "--2022-05-27 12:53:21-- https://files.rcsb.org/download/5YH2.cif\n", + "Resolving files.rcsb.org (files.rcsb.org)... 132.249.210.222\n", + "Connecting to files.rcsb.org (files.rcsb.org)|132.249.210.222|:443... connected.\n", + "HTTP request sent, awaiting response... 200 OK\n", + "Length: unspecified [application/octet-stream]\n", + "Saving to: ‘data/5YH2.cif.1’\n", + "\n", + "5YH2.cif.1 [ <=> ] 1.39M --.-KB/s in 0.09s \n", + "\n", + "2022-05-27 12:53:21 (15.5 MB/s) - ‘data/5YH2.cif.1’ saved [1456779]\n", + "\n" + ] + } + ], + "source": [ + "!wget https://files.rcsb.org/download/5YH2.cif -P data/ # save this to the data folder in colab" + ] + }, + { + "cell_type": "markdown", + "id": "h7EdhncQCWtU", + "metadata": { + "id": "h7EdhncQCWtU" + }, + "source": [ + "Load chain C from this CIF file:" + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "id": "f4d17649", + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "f4d17649", + "outputId": "42bf8119-8bdf-4612-f7cb-928b74f1b2a5" + }, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Found 6 chains: ['A' 'C' 'B' 'D' 'A' 'B'] \n", + "\n", + "Loaded chain C\n", + "\n", + "Native sequence:\n", + "SVLQSLFEHPLYRTVLPDLTEEDTLFNLNAEIRLYPKAASESYPNWLRFHIGINRYELYSRHNPVIAALLRDLLSQKISSVGMKSGGTQLKLIMSFQNYGQALFKPMKQTREQETPPDFFYFSDFERHNAEIAAFHLDRILDFRRVPPVAGRLVNMTREIRDVTRDKKLWRTFFVSPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLALAKRKTWRNPWRRSYHKRKKAEWEVDPDYCDEVKQTPPYDRGTRLLDIMDMTIFDFLMGNMDRHHYETFEKFGNDTFIIHLDNGRGFGKHSHDEMSILVPLTQCCRVKRSTYLRLQLLAKEEYKLSSLMEESLLQDRLVPVLIKPHLEALDRRLRLVLKVLSDCVEKDGFSAVVENDLD\n" + ] + } + ], + "source": [ + "fpath = 'data/5YH2.cif' # .pdb format is also acceptable\n", + "chain_id = 'C'\n", + "structure = esm.inverse_folding.util.load_structure(fpath, chain_id)\n", + "coords, native_seq = esm.inverse_folding.util.extract_coords_from_structure(structure)\n", + "print('Native sequence:')\n", + "print(native_seq)" + ] + }, + { + "cell_type": "markdown", + "id": "2YmG4jc5CCUJ", + "metadata": { + "id": "2YmG4jc5CCUJ" + }, + "source": [ + "Visualize chain C in this CIF file:" + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "id": "V4BbLME4DbZQ", + "metadata": { + "id": "V4BbLME4DbZQ" + }, + "outputs": [], + "source": [ + "!pip install -q py3Dmol" + ] + }, + { + "cell_type": "code", + "execution_count": 7, + "id": "PDUHDRMMBbZu", + "metadata": { + "id": "PDUHDRMMBbZu" + }, + "outputs": [], + "source": [ + "try:\n", + " import py3Dmol\n", + "\n", + " def view_pdb(fpath, chain_id):\n", + " with open(fpath) as ifile:\n", + " system = \"\".join([x for x in ifile])\n", + "\n", + " view = py3Dmol.view(width=600, height=400)\n", + " view.addModelsAsFrames(system)\n", + " view.setStyle({'model': -1, 'chain': chain_id}, {\"cartoon\": {'color': 'spectrum'}})\n", + " view.zoomTo()\n", + " view.show()\n", + "\n", + "except ImportError:\n", + " def view_pdb(fpath, chain_id):\n", + " print(\"Install py3Dmol to visualize, or use pymol\")" + ] + }, + { + "cell_type": "code", + "execution_count": 8, + "id": "Q9MJYWMJJxVx", + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/", + "height": 417 + }, + "id": "Q9MJYWMJJxVx", + "outputId": "ddd957ea-7512-43bf-f730-4df188bf3393" + }, + "outputs": [ + { + "data": { + "application/3dmoljs_load.v0": "
\n

You appear to be running in JupyterLab (or JavaScript failed to load for some other reason). You need to install the 3dmol extension:
\n jupyter labextension install jupyterlab_3dmol

\n
\n", + "text/html": [ + "
\n", + "

You appear to be running in JupyterLab (or JavaScript failed to load for some other reason). You need to install the 3dmol extension:
\n", + " jupyter labextension install jupyterlab_3dmol

\n", + "
\n", + "" + ] + }, + "metadata": {}, + "output_type": "display_data" + } + ], + "source": [ + "view_pdb(fpath, chain_id)" + ] + }, + { + "cell_type": "markdown", + "id": "oKqm6n9HCk4Q", + "metadata": { + "id": "oKqm6n9HCk4Q" + }, + "source": [ + "Sample sequence and calculate sequence recovery:" + ] + }, + { + "cell_type": "code", + "execution_count": 9, + "id": "50bb20b3", + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "50bb20b3", + "outputId": "27c6cb60-64b8-4f97-c0dd-c6e66b7af5e4" + }, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Sampled sequence: STLKQWFHSPLTLNDDPYSSAEDVLFSPTRVLSLLPALQGRDLPDFILFWTGIDKFHMYKIDSPVISSLRKRLRTERVREVQQLMGGSKLVLKFTFEDLGAAMFKPVAASTSEETPPHWEFWEVKKTSRAVVASWHLDYLFQLKSTAPSAGRVLNLVRDIRDVTSDSQLQSTFVQTPSRQLCFYGSNTFRSNLRDAICGNRDEIWGSVIAELPHANVALRDVYTSPWKRSKTKFKISLWRTKPDYAKYIRLTPLFKEGDNFLELQKAFIFDYLQGNDDRAKWVAFQKFGVDQELLICDNGAGFGRFDHLDMEILSPLQQGAYFSQNLYDHVIALQSSDYSMSRLMKSVLKADERYPILSEPYLLQLDTRLETVRKILDDCVREIGSNNSLIVEKL\n", + "Sequence recovery: 0.3468354430379747\n" + ] + } + ], + "source": [ + "import numpy as np\n", + "\n", + "sampled_seq = model.sample(coords, temperature=1)\n", + "print('Sampled sequence:', sampled_seq)\n", + "\n", + "recovery = np.mean([(a==b) for a, b in zip(native_seq, sampled_seq)])\n", + "print('Sequence recovery:', recovery)" + ] + }, + { + "cell_type": "code", + "execution_count": 10, + "id": "c82f7a48", + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "c82f7a48", + "outputId": "cfb96fa3-c7ad-4331-c070-0ef45b467608" + }, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Sampled sequence: ERLRAWWASPLTQLPDPGLSEEDLLFDPEELLALLPEEEEEELPAWLRFWTGIRRRRLYERESPDVEELLRRLRTARVRRVGQKSGGRSLVLRFEFEDLGSAGFKPRVAELDEETPPEWGFWEVLQRARAVVAAYRLDRLLDLRQVPPAAGRRLDLVTELRDVTDDEELRSTFFVTPEEELCFYGRCEFRCDREHALCGRPDVVEGALVAELPDERIAPRGVYLNPWAHARERDVEALWEVDPDYCEYVRRLPPFREGRLLLELANAYVFDFLMGNADRHTFSTFERFGLDTFLLLLDNGFGFGRADYLDERILRPLEQCCLLSERLYRRLLALSEEEFSLEELMEEELGRDELWPVLARPFLRQLDRRLRRVLEVLEECEEECGREEVLVREEG\n", + "Sequence recovery: 0.4582278481012658\n" + ] + } + ], + "source": [ + "# Lower sampling temperature typically results in higher sequence recovery but less diversity\n", + "\n", + "sampled_seq = model.sample(coords, temperature=1e-6)\n", + "print('Sampled sequence:', sampled_seq)\n", + "\n", + "recovery = np.mean([(a==b) for a, b in zip(native_seq, sampled_seq)])\n", + "print('Sequence recovery:', recovery)" + ] + }, + { + "cell_type": "markdown", + "id": "310b282a", + "metadata": { + "id": "310b282a" + }, + "source": [ + "## Conditional sequence log-likelihoods for given backbone coordinates\n", + "\n", + "The log-likelihood scores could be used to predict mutational effects. See also our [script](https://github.com/facebookresearch/esm/tree/main/examples/inverse_folding#scoring-sequences) for batch scoring," + ] + }, + { + "cell_type": "code", + "execution_count": 11, + "id": "c7d41032", + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "c7d41032", + "outputId": "6919b9bf-9abb-44c0-8c40-446f4dcf63a8", + "scrolled": true + }, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "average log-likelihood on entire sequence: -1.61 (perplexity 5.01)\n", + "average log-likelihood excluding missing coordinates: -1.61 (perplexity 5.01)\n" + ] + } + ], + "source": [ + "ll_fullseq, ll_withcoord = esm.inverse_folding.util.score_sequence(model, alphabet, coords, native_seq)\n", + "\n", + "print(f'average log-likelihood on entire sequence: {ll_fullseq:.2f} (perplexity {np.exp(-ll_fullseq):.2f})')\n", + "print(f'average log-likelihood excluding missing coordinates: {ll_withcoord:.2f} (perplexity {np.exp(-ll_withcoord):.2f})')" + ] + }, + { + "cell_type": "markdown", + "id": "9ab34ef2", + "metadata": { + "id": "9ab34ef2" + }, + "source": [ + "## Masking part of the backbone coordinates\n", + "To partially mask backbone coordinates, simply set the masked coordinates to np.inf. \n", + "\n", + "Typically, the sequence perplexity will be higher on masked regions than on unmasked regions." + ] + }, + { + "cell_type": "code", + "execution_count": 12, + "id": "da7f4c7a", + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "da7f4c7a", + "outputId": "16613c79-8060-47b5-deb1-10ab5d157dbf", + "scrolled": true + }, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "average log-likelihood on entire sequence: -1.64 (perplexity 5.16)\n", + "average log-likelihood excluding missing coordinates: -1.59 (perplexity 4.92)\n" + ] + } + ], + "source": [ + "from copy import deepcopy\n", + "masked_coords = deepcopy(coords)\n", + "masked_coords[:15] = np.inf # mask the first 10 residues\n", + "ll_fullseq, ll_withcoord = esm.inverse_folding.util.score_sequence(model, alphabet, masked_coords, native_seq)\n", + "\n", + "print(f'average log-likelihood on entire sequence: {ll_fullseq:.2f} (perplexity {np.exp(-ll_fullseq):.2f})')\n", + "print(f'average log-likelihood excluding missing coordinates: {ll_withcoord:.2f} (perplexity {np.exp(-ll_withcoord):.2f})')" + ] + }, + { + "cell_type": "markdown", + "id": "17cb6adc", + "metadata": { + "id": "17cb6adc" + }, + "source": [ + "## Extract encoder output as structure representation\n", + "The encoder output may also be used as a representation for the structure.\n", + "\n", + "For a set of input coordinates with L amino acids, the encoder output will have shape L x 512." + ] + }, + { + "cell_type": "code", + "execution_count": 13, + "id": "0561236d", + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "0561236d", + "outputId": "a07279d1-a668-439c-8d7e-00b221bdf6d2" + }, + "outputs": [ + { + "data": { + "text/plain": [ + "(395, torch.Size([395, 512]))" + ] + }, + "execution_count": 13, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "rep = esm.inverse_folding.util.get_encoder_output(model, alphabet, coords)\n", + "len(coords), rep.shape" + ] + } + ], + "metadata": { + "accelerator": "GPU", + "colab": { + "collapsed_sections": [], + "include_colab_link": true, + "name": "Inverse Folding with ESM-IF1.ipynb", + "provenance": [] + }, + "kernelspec": { + "display_name": "Python 3 (ipykernel)", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.9.7" + } + }, + "nbformat": 4, + "nbformat_minor": 5 +} diff --git a/esm/source/examples/inverse_folding/notebook_multichain.ipynb b/esm/source/examples/inverse_folding/notebook_multichain.ipynb new file mode 100644 index 0000000000000000000000000000000000000000..4b64a59d68bb276c1bc536580c92b7846236ab21 --- /dev/null +++ b/esm/source/examples/inverse_folding/notebook_multichain.ipynb @@ -0,0 +1,606 @@ +{ + "cells": [ + { + "cell_type": "markdown", + "id": "81e7a8b2", + "metadata": { + "colab_type": "text", + "id": "view-in-github" + }, + "source": [ + "\"Open" + ] + }, + { + "cell_type": "markdown", + "id": "43GQPw7R_ZbY", + "metadata": { + "id": "43GQPw7R_ZbY" + }, + "source": [ + "# Inverse folding with ESM-IF1\n", + "\n", + "The ESM-IF1 inverse folding model is built for predicting protein sequences from their backbone atom coordinates. We provide examples here 1) to sample sequence designs for a given structure and 2) to score sequences for a given structure.\n", + "\n", + "Trained with 12M protein structures predicted by AlphaFold2, the ESM-IF1 model consists of invariant geometric input processing layers followed by a sequence-to-sequence transformer, and achieves 51% native sequence recovery on structurally held-out backbones. The model is also trained with span masking to tolerate missing backbone coordinates and therefore can predict sequences for partially masked structures.\n", + "\n", + "See [GitHub README](https://github.com/facebookresearch/esm/tree/main/examples/inverse_folding) for the complete user guide, and see our [bioRxiv pre-print](https://doi.org/10.1101/2022.04.10.487779) for more details." + ] + }, + { + "cell_type": "markdown", + "id": "8c6TDUVupgNn", + "metadata": { + "id": "8c6TDUVupgNn" + }, + "source": [ + "## Environment setup (colab)\n", + "This step might take up to 10 minutes the first time. \n", + "\n", + "If using a local jupyter environment, instead of the following, we recommend configuring a conda environment upon first use in command line:\n", + "```\n", + "conda create -n inverse python=3.9\n", + "conda activate inverse\n", + "conda install pytorch cudatoolkit=11.3 -c pytorch\n", + "conda install pyg -c pyg -c conda-forge\n", + "conda install pip\n", + "pip install biotite\n", + "pip install git+https://github.com/facebookresearch/esm.git\n", + "```\n", + "\n", + "Afterwards, `conda activate inverse` to activate this environment before starting `jupyter notebook`.\n", + "\n", + "Below is the setup for colab notebooks:\n", + "\n", + "We recommend using GPU runtimes on colab (Menu bar -> Runtime -> Change runtime type -> Hardware accelerator -> GPU)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "nLOymXwdwUXo", + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "nLOymXwdwUXo", + "outputId": "894a9af0-d8e9-44f3-e869-830a3e3e90ad" + }, + "outputs": [], + "source": [ + "# Colab environment setup\n", + "\n", + "# Install the correct version of Pytorch Geometric.\n", + "import torch\n", + "\n", + "def format_pytorch_version(version):\n", + " return version.split('+')[0]\n", + "\n", + "TORCH_version = torch.__version__\n", + "TORCH = format_pytorch_version(TORCH_version)\n", + "\n", + "def format_cuda_version(version):\n", + " return 'cu' + version.replace('.', '')\n", + "\n", + "CUDA_version = torch.version.cuda\n", + "CUDA = format_cuda_version(CUDA_version)\n", + "\n", + "!pip install -q torch-scatter -f https://data.pyg.org/whl/torch-{TORCH}+{CUDA}.html\n", + "!pip install -q torch-sparse -f https://data.pyg.org/whl/torch-{TORCH}+{CUDA}.html\n", + "!pip install -q torch-cluster -f https://data.pyg.org/whl/torch-{TORCH}+{CUDA}.html\n", + "!pip install -q torch-spline-conv -f https://data.pyg.org/whl/torch-{TORCH}+{CUDA}.html\n", + "!pip install -q torch-geometric\n", + "\n", + "# Install esm\n", + "!pip install -q git+https://github.com/facebookresearch/esm.git\n", + "\n", + "# Install biotite\n", + "!pip install -q biotite" + ] + }, + { + "cell_type": "markdown", + "id": "EhDI4ZIX0Z4w", + "metadata": { + "id": "EhDI4ZIX0Z4w" + }, + "source": [ + "### Verify that pytorch-geometric is correctly installed\n", + "\n", + "If the notebook crashes at the import, there is likely an issue with the version of torch_geometric and torch_sparse being incompatible with the torch version." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "1-HvBXt1wWPu", + "metadata": { + "id": "1-HvBXt1wWPu" + }, + "outputs": [], + "source": [ + "## Verify that pytorch-geometric is correctly installed\n", + "import torch_geometric\n", + "import torch_sparse\n", + "from torch_geometric.nn import MessagePassing" + ] + }, + { + "cell_type": "markdown", + "id": "18544eee", + "metadata": { + "id": "18544eee" + }, + "source": [ + "## Load model\n", + "This steps takes a few minutes for the model to download" + ] + }, + { + "cell_type": "code", + "execution_count": 1, + "id": "14d8f393", + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "14d8f393", + "outputId": "d84afad9-0cd7-4e96-bedd-2bdae90229b0" + }, + "outputs": [ + { + "name": "stderr", + "output_type": "stream", + "text": [ + "/home/chloehsu/inverse_opensource/esm_public_fork/esm/esm/pretrained.py:174: UserWarning: Regression weights not found, predicting contacts will not produce correct results.\n", + " warnings.warn(\n" + ] + } + ], + "source": [ + "import esm\n", + "model, alphabet = esm.pretrained.esm_if1_gvp4_t16_142M_UR50()\n", + "# use eval mode for deterministic output e.g. without random dropout\n", + "model = model.eval()" + ] + }, + { + "cell_type": "markdown", + "id": "2a6ed9bb", + "metadata": { + "id": "2a6ed9bb" + }, + "source": [ + "## Load structure from PDB or CIF files\n", + "\n", + "As an example, let's look at Golgi Casein Kinase, the [PDB Molecule of the Month from January 2022](https://pdb101.rcsb.org/motm/265).\n", + "\n", + "Milk is a complex mixture of proteins, fats, and nutrients that provides everything that a growing infant needs. Most of the protein in cow’s milk is casein, whereas human milk has lesser amounts of casein. \n", + "\n", + "The Golgi casein kinase (PDB entry 5YH2) adds phosphates to casein and also to many other types of secreted proteins. It is most active as a complex of two similar types of proteins. Fam20C is the catalytic subunit. It binds to casein and transfers a phosphate from ATP to the protein.\n", + "\n", + "In this example, let's load chains A, B, C, and D, and try to redesign chain A.\n", + "\n", + "You may also upload your own CIF or PDB file and specify the chain id." + ] + }, + { + "cell_type": "code", + "execution_count": 2, + "id": "a8hwuySfBDig", + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "a8hwuySfBDig", + "outputId": "fbe2c984-3e79-4b56-981f-cc11441e9d8e" + }, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "--2022-06-22 04:07:19-- https://files.rcsb.org/download/5YH2.cif\n", + "Resolving files.rcsb.org (files.rcsb.org)... 132.249.210.234\n", + "Connecting to files.rcsb.org (files.rcsb.org)|132.249.210.234|:443... connected.\n", + "HTTP request sent, awaiting response... 200 OK\n", + "Length: unspecified [application/octet-stream]\n", + "Saving to: ‘data/5YH2.cif.3’\n", + "\n", + "5YH2.cif.3 [ <=> ] 1.39M --.-KB/s in 0.09s \n", + "\n", + "2022-06-22 04:07:19 (15.6 MB/s) - ‘data/5YH2.cif.3’ saved [1456779]\n", + "\n" + ] + } + ], + "source": [ + "!wget https://files.rcsb.org/download/5YH2.cif -P data/ # save this to the data folder in colab" + ] + }, + { + "cell_type": "markdown", + "id": "h7EdhncQCWtU", + "metadata": { + "id": "h7EdhncQCWtU" + }, + "source": [ + "Load chains A, B, C, D from this CIF file:" + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "id": "f4d17649", + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "f4d17649", + "outputId": "42bf8119-8bdf-4612-f7cb-928b74f1b2a5" + }, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Loaded chains: ['A', 'C', 'B', 'D']\n", + "\n", + "Chain A native sequence:\n", + "SSKLQALFAHPLYNVPEEPPLLGAEDSLLASQEALRYYRRKVARWNRRHKMDPPLQLRLEASWVQFHLGINRHGLYSRSSPVVSKLLQDMRHFPTISADYSQDEKALLGACDCTQIVKPSGVHLKLVLRFSDFGKAMFKPMRQQRDEETPVDFFYFIDFQRHNAEIAAFHLDRILDFRRVPPTVGRIVNVTKEILEVTKNEILQSVFFVSPASNVCFFAKCPYMCKTEYAVCGKPHLLEGSLSAFLPSLNLAPRLSVPNPWIRSYTLAGKEEWEVNPLYCDTVKQIYPYNNSQRLLNVIDMAIFDFLIGNMDRHHYEMFTKFGDDGFLIHLDNARGFGRHSHDEISILSPLSQCCMIKKKTLLHLQLLAQADYRLSDVMRESLLEDQLSPVLTEPHLLALDRRLQTILRTVEGCIVAHGQQSVIVDGP\n", + "\n", + "\n", + "Chain B native sequence:\n", + "SSKLQALFAHPLYNVPEEPPLLGAEDSLLASQEALRYYRRKVARWNRRHKMYPPLQLRLEASWVQFHLGINRHGLYSRSSPVVSKLLQDMRHFPTISADYSQDEKALLGACDCTQIVKPSGVHLKLVLRFSDFGKAMFKPMRQQRDEETPVDFFYFIDFQRHNAEIAAFHLDRILDFRRVPPTVGRIVNVTKEILEVTKNEILQSVFFVSPASNVCFFAKCPYMCKTEYAVCGKPHLLEGSLSAFLPSLNLAPRLSVPNPWIRSYTLAGKEEWEVNPLYCDTVKQIYPYNNSQRLLNVIDMAIFDFLIGNMDRHHYEMFTKFGDDGFLIHLDNARGFGRHSHDEISILSPLSQCCMIKKKTLLHLQLLAQADYRLSDVMRESLLEDQLSPVLTEPHLLALDRRLQTILRTVEGCIVAHGQQSVIVDGP\n", + "\n", + "\n", + "Chain C native sequence:\n", + "SVLQSLFEHPLYRTVLPDLTEEDTLFNLNAEIRLYPKAASESYPNWLRFHIGINRYELYSRHNPVIAALLRDLLSQKISSVGMKSGGTQLKLIMSFQNYGQALFKPMKQTREQETPPDFFYFSDFERHNAEIAAFHLDRILDFRRVPPVAGRLVNMTREIRDVTRDKKLWRTFFVSPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLALAKRKTWRNPWRRSYHKRKKAEWEVDPDYCDEVKQTPPYDRGTRLLDIMDMTIFDFLMGNMDRHHYETFEKFGNDTFIIHLDNGRGFGKHSHDEMSILVPLTQCCRVKRSTYLRLQLLAKEEYKLSSLMEESLLQDRLVPVLIKPHLEALDRRLRLVLKVLSDCVEKDGFSAVVENDLD\n", + "\n", + "\n", + "Chain D native sequence:\n", + "SVLQSLFEHPLYRTVLPDLTEEDTLFNLNAEIRLYPKAESYPNWLRFHIGINRYELYSRHNPVIAALLRDLLSQKISSVGMKSGGTQLKLIMSFQNYGQALFKPMKQTREQETPPDFFYFSDFERHNAEIAAFHLDRILDFRRVPPVAGRLVNMTREIRDVTRDKKLWRTFFVSPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLALAKRKTWRNPWRRSYHKRKKAEWEVDPDYCDEVKQTPPYDRGTRLLDIMDMTIFDFLMGNMDRHHYETFEKFGNDTFIIHLDNGRGFGKHSHDEMSILVPLTQCCRVKRSTYLRLQLLAKEEYKLSSLMEESLLQDRLVPVLIKPHLEALDRRLRLVLKVLSDCVEKDGFSAVVENDLDG\n", + "\n", + "\n" + ] + } + ], + "source": [ + "fpath = 'data/5YH2.cif' # .pdb format is also acceptable\n", + "chain_ids = ['A', 'B', 'C', 'D']\n", + "structure = esm.inverse_folding.util.load_structure(fpath, chain_ids)\n", + "coords, native_seqs = esm.inverse_folding.multichain_util.extract_coords_from_complex(structure)\n", + "\n", + "print(f'Loaded chains: {list(coords.keys())}\\n')\n", + "\n", + "for chain_id in chain_ids:\n", + " print(f'Chain {chain_id} native sequence:')\n", + " print(native_seqs[chain_id])\n", + " print('\\n')" + ] + }, + { + "cell_type": "markdown", + "id": "2YmG4jc5CCUJ", + "metadata": { + "id": "2YmG4jc5CCUJ" + }, + "source": [ + "Visualize chain A in this CIF file:" + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "id": "V4BbLME4DbZQ", + "metadata": { + "id": "V4BbLME4DbZQ" + }, + "outputs": [], + "source": [ + "!pip install -q py3Dmol" + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "id": "PDUHDRMMBbZu", + "metadata": { + "id": "PDUHDRMMBbZu" + }, + "outputs": [], + "source": [ + "try:\n", + " import py3Dmol\n", + "\n", + " def view_pdb(fpath, chain_ids, colors=['red','blue','green']):\n", + " with open(fpath) as ifile:\n", + " system = \"\".join([x for x in ifile])\n", + "\n", + " view = py3Dmol.view(width=600, height=400)\n", + " view.addModelsAsFrames(system)\n", + " for chain_id, color in zip(chain_ids, colors):\n", + " view.setStyle({'model': -1, 'chain': chain_id}, {\"cartoon\": {'color': color}})\n", + " view.zoomTo()\n", + " view.show()\n", + "\n", + "except ImportError:\n", + " def view_pdb(fpath, chain_id):\n", + " print(\"Install py3Dmol to visualize, or use pymol\")" + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "id": "Q9MJYWMJJxVx", + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/", + "height": 417 + }, + "id": "Q9MJYWMJJxVx", + "outputId": "ddd957ea-7512-43bf-f730-4df188bf3393" + }, + "outputs": [ + { + "data": { + "application/3dmoljs_load.v0": "
\n

You appear to be running in JupyterLab (or JavaScript failed to load for some other reason). You need to install the 3dmol extension:
\n jupyter labextension install jupyterlab_3dmol

\n
\n", + "text/html": [ + "
\n", + "

You appear to be running in JupyterLab (or JavaScript failed to load for some other reason). You need to install the 3dmol extension:
\n", + " jupyter labextension install jupyterlab_3dmol

\n", + "
\n", + "" + ] + }, + "metadata": {}, + "output_type": "display_data" + } + ], + "source": [ + "view_pdb(fpath, ['A'])" + ] + }, + { + "cell_type": "markdown", + "id": "oKqm6n9HCk4Q", + "metadata": { + "id": "oKqm6n9HCk4Q" + }, + "source": [ + "## Sample sequence and calculate sequence recovery:" + ] + }, + { + "cell_type": "code", + "execution_count": 7, + "id": "99d74757", + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Sequence recovery: 0.441588785046729\n" + ] + } + ], + "source": [ + "import numpy as np\n", + "\n", + "target_chain_id = 'A'\n", + "sampled_seq = esm.inverse_folding.multichain_util.sample_sequence_in_complex(\n", + " model, coords, target_chain_id, temperature=1.)\n", + "\n", + "recovery = np.mean([(a==b) for a, b in zip(native_seqs[target_chain_id], sampled_seq)])\n", + "print('Sequence recovery:', recovery)" + ] + }, + { + "cell_type": "code", + "execution_count": 8, + "id": "3af7d869", + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Sequence recovery: 0.5046728971962616\n" + ] + } + ], + "source": [ + "# Lower sampling temperature typically results in higher sequence recovery but less diversity\n", + "\n", + "target_chain_id = 'A'\n", + "sampled_seq = esm.inverse_folding.multichain_util.sample_sequence_in_complex(\n", + " model, coords, target_chain_id, temperature=1e-6)\n", + "\n", + "recovery = np.mean([(a==b) for a, b in zip(native_seqs[target_chain_id], sampled_seq)])\n", + "print('Sequence recovery:', recovery)" + ] + }, + { + "cell_type": "markdown", + "id": "310b282a", + "metadata": { + "id": "310b282a" + }, + "source": [ + "## Conditional sequence log-likelihoods for given backbone coordinates\n", + "\n", + "The log-likelihood scores could be used to predict mutational effects. See also our [script](https://github.com/facebookresearch/esm/tree/main/examples/inverse_folding#scoring-sequences) for batch scoring," + ] + }, + { + "cell_type": "code", + "execution_count": 9, + "id": "2e8bf940", + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "average log-likelihood on entire sequence: -1.50 (perplexity 4.50)\n", + "average log-likelihood excluding missing coordinates: -1.50 (perplexity 4.50)\n" + ] + } + ], + "source": [ + "target_chain_id = 'A'\n", + "target_seq = native_seqs[target_chain_id]\n", + "ll_fullseq, ll_withcoord = esm.inverse_folding.multichain_util.score_sequence_in_complex(\n", + " model, alphabet, coords, target_chain_id, target_seq, padding_length=10)\n", + "print(f'average log-likelihood on entire sequence: {ll_fullseq:.2f} (perplexity {np.exp(-ll_fullseq):.2f})')\n", + "print(f'average log-likelihood excluding missing coordinates: {ll_withcoord:.2f} (perplexity {np.exp(-ll_withcoord):.2f})')" + ] + }, + { + "cell_type": "markdown", + "id": "9ab34ef2", + "metadata": { + "id": "9ab34ef2" + }, + "source": [ + "## Masking part of the backbone coordinates\n", + "To partially mask backbone coordinates, simply set the masked coordinates to np.inf. \n", + "\n", + "Typically, the sequence perplexity will be higher on masked regions than on unmasked regions." + ] + }, + { + "cell_type": "code", + "execution_count": 10, + "id": "4539a9cb", + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "average log-likelihood on entire sequence: -1.58 (perplexity 4.87)\n", + "average log-likelihood excluding missing coordinates: -1.54 (perplexity 4.65)\n" + ] + } + ], + "source": [ + "target_chain_id = 'A'\n", + "target_seq = native_seqs[target_chain_id]\n", + "\n", + "from copy import deepcopy\n", + "masked_coords = deepcopy(coords)\n", + "masked_coords[target_chain_id][:15] = np.inf # mask the first 15 residues\n", + "\n", + "ll_fullseq, ll_withcoord = esm.inverse_folding.multichain_util.score_sequence_in_complex(\n", + " model, alphabet, masked_coords, target_chain_id, target_seq, padding_length=10)\n", + "print(f'average log-likelihood on entire sequence: {ll_fullseq:.2f} (perplexity {np.exp(-ll_fullseq):.2f})')\n", + "print(f'average log-likelihood excluding missing coordinates: {ll_withcoord:.2f} (perplexity {np.exp(-ll_withcoord):.2f})')" + ] + }, + { + "cell_type": "markdown", + "id": "17cb6adc", + "metadata": { + "id": "17cb6adc" + }, + "source": [ + "## Extract encoder output as structure representation\n", + "The encoder output may also be used as a representation for the structure.\n", + "\n", + "For a set of input coordinates with L amino acids, the encoder output will have shape L x 512." + ] + }, + { + "cell_type": "code", + "execution_count": 11, + "id": "0561236d", + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "0561236d", + "outputId": "a07279d1-a668-439c-8d7e-00b221bdf6d2" + }, + "outputs": [ + { + "data": { + "text/plain": [ + "(428, torch.Size([428, 512]))" + ] + }, + "execution_count": 11, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "target_chain_id = 'A'\n", + "rep = esm.inverse_folding.multichain_util.get_encoder_output_for_complex(model, alphabet, coords, target_chain_id)\n", + "len(coords[target_chain_id]), rep.shape" + ] + } + ], + "metadata": { + "accelerator": "GPU", + "colab": { + "collapsed_sections": [], + "include_colab_link": true, + "name": "Inverse Folding with ESM-IF1.ipynb", + "provenance": [] + }, + "kernelspec": { + "display_name": "Python 3 (ipykernel)", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.9.7" + } + }, + "nbformat": 4, + "nbformat_minor": 5 +} diff --git a/esm/source/examples/inverse_folding/output/5YH2_mutated_seqs_scores.csv b/esm/source/examples/inverse_folding/output/5YH2_mutated_seqs_scores.csv new file mode 100644 index 0000000000000000000000000000000000000000..8e24d43194e4442723af5f1066236c92d7c3eef4 --- /dev/null +++ b/esm/source/examples/inverse_folding/output/5YH2_mutated_seqs_scores.csv @@ -0,0 +1,5 @@ +seqid,log_likelihood +mut_1,-1.611882209777832 +mut_2,-1.615426778793335 +mut_3,-1.614095687866211 +mut_4,-1.6152666807174683 diff --git a/esm/source/examples/inverse_folding/output/sampled_sequences.fasta b/esm/source/examples/inverse_folding/output/sampled_sequences.fasta new file mode 100644 index 0000000000000000000000000000000000000000..82da9e196b659be31b95af08c93c099472a1912e --- /dev/null +++ b/esm/source/examples/inverse_folding/output/sampled_sequences.fasta @@ -0,0 +1,6 @@ +>sampled_seq_1 +AAVTRWWSTPVTSVQDPGRNNDDLLFDKNEMLKLLPSTDSSGYPNHIAFWEQINRYKLYDEVSPTIQNLDLEMRNLQVRTVSQLSNGRTLKLHFSFSDNGKALFKPMVSLTEDENPIDDATWEYFETSRAVIAAYKLDKLLNLRNVPPAAGRSVHIISQIRDVSKDQNLDNTFHETEDNKLCFWGKCHDRCDEASAICGNPNSVDGVIVAQLPDSIFAEQENHNSPWAHSCKTDVTTWQAVNPAFCNDIFKTKPLRHGDFKLALADNYLFAFLQGNCDDHSYMEFRSFGTDTRILMLDNGYGFGRYSYNNKDILQPLQQCAQVRQSSKVKLDLLNETIFDLRVLMEEVLSHDLSFPILYSPYLKRLNRNLQIVVEEFELSRQRVGVNNTYKMNHE +>sampled_seq_2 +VKFDAWLSNPITTGKVPGLTETDFLFKPQEMEALYPTLEGEPLPDHIRFHVQINRYFMYDKDSPVIKRLLRRLEKAAIKSVGQLKGGDQLVLEFRFEDFGRALFKPKLNSLEEEVPPQFDWFERHDTCQAEVASYELDQILDLHNCPPTQARPIDFQKDLWNVSDDKELLSTANVTPWNQLCFYGKNKFQSSHETAICGTYDVIDGAVQAQLPHQIIAPRSDNHNPWARTKHQYIDSSWQTNPTYYDYIRTQPYHQTKYIVGTMTNEYCHYFLEGNADRHHYKTWTKFGEDQNLIALDTGRGFGRKNFMDLDILKPLSQGKWMSEQAYQRKKKLMSRDYSLAELMNESLSESALYPVLSEPYLIQLDTRLQIILQAMEFTIKEKGIDLFLRKEFD +>sampled_seq_3 +CVARRWWAHPTTGEADPPQSAADLLFKTVDAYTMLPREARQELPHHLKFHRQIEKTRLYATKSPTVTALLQDLQSTKILRVSQFSGGRSLRLRFVFDDGGSSAFKPLVSELHAEVPPHWYNFQRSDVAQSLIASYHLNRVLDLRMTPPCAARLVDLVKELRDVSDDAELLSTFFVTPEHELAFFGTSYYRSGLETALVGRPRTVAGSHIAELPDETLSPRGSFDCPWAYSEKDRVSTYWSFDPKASARSDKSPQYRFGTILLNLANTHVFNFLMGNKDAHNFDTFTAFGKDQFAVQIDNGCGFGRYSHMDRDVLVPLTQSVVVRRRLYDRLRSLAQEEYGMRDLLAEVLAQDKCYPVLVQPFLDRLDETLNLVLDVMDQNRKLRGDDRVLLMESS diff --git a/esm/source/examples/inverse_folding/sample_sequences.py b/esm/source/examples/inverse_folding/sample_sequences.py new file mode 100644 index 0000000000000000000000000000000000000000..3a1269307fb4bf277fb469097644bb9bc587de47 --- /dev/null +++ b/esm/source/examples/inverse_folding/sample_sequences.py @@ -0,0 +1,124 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. +# +# Sample sequences based on a given structure (multinomial sampling, no beam search). +# +# usage: sample_sequences.py [-h] [--chain CHAIN] [--temperature TEMPERATURE] +# [--outpath OUTPATH] [--num-samples NUM_SAMPLES] pdbfile + +import argparse +import numpy as np +from pathlib import Path +import torch + +import esm +import esm.inverse_folding + + +def sample_seq_singlechain(model, alphabet, args): + if torch.cuda.is_available() and not args.nogpu: + model = model.cuda() + print("Transferred model to GPU") + coords, native_seq = esm.inverse_folding.util.load_coords(args.pdbfile, args.chain) + print('Native sequence loaded from structure file:') + print(native_seq) + + print(f'Saving sampled sequences to {args.outpath}.') + + Path(args.outpath).parent.mkdir(parents=True, exist_ok=True) + with open(args.outpath, 'w') as f: + for i in range(args.num_samples): + print(f'\nSampling.. ({i+1} of {args.num_samples})') + sampled_seq = model.sample(coords, temperature=args.temperature, device=torch.device('cuda')) + print('Sampled sequence:') + print(sampled_seq) + f.write(f'>sampled_seq_{i+1}\n') + f.write(sampled_seq + '\n') + + recovery = np.mean([(a==b) for a, b in zip(native_seq, sampled_seq)]) + print('Sequence recovery:', recovery) + + +def sample_seq_multichain(model, alphabet, args): + if torch.cuda.is_available() and not args.nogpu: + model = model.cuda() + print("Transferred model to GPU") + structure = esm.inverse_folding.util.load_structure(args.pdbfile) + coords, native_seqs = esm.inverse_folding.multichain_util.extract_coords_from_complex(structure) + target_chain_id = args.chain + native_seq = native_seqs[target_chain_id] + print('Native sequence loaded from structure file:') + print(native_seq) + print('\n') + + print(f'Saving sampled sequences to {args.outpath}.') + + Path(args.outpath).parent.mkdir(parents=True, exist_ok=True) + with open(args.outpath, 'w') as f: + for i in range(args.num_samples): + print(f'\nSampling.. ({i+1} of {args.num_samples})') + sampled_seq = esm.inverse_folding.multichain_util.sample_sequence_in_complex( + model, coords, target_chain_id, temperature=args.temperature) + print('Sampled sequence:') + print(sampled_seq) + f.write(f'>sampled_seq_{i+1}\n') + f.write(sampled_seq + '\n') + + recovery = np.mean([(a==b) for a, b in zip(native_seq, sampled_seq)]) + print('Sequence recovery:', recovery) + + +def main(): + parser = argparse.ArgumentParser( + description='Sample sequences based on a given structure.' + ) + parser.add_argument( + 'pdbfile', type=str, + help='input filepath, either .pdb or .cif', + ) + parser.add_argument( + '--chain', type=str, + help='chain id for the chain of interest', default=None, + ) + parser.add_argument( + '--temperature', type=float, + help='temperature for sampling, higher for more diversity', + default=1., + ) + parser.add_argument( + '--outpath', type=str, + help='output filepath for saving sampled sequences', + default='output/sampled_seqs.fasta', + ) + parser.add_argument( + '--num-samples', type=int, + help='number of sequences to sample', + default=1, + ) + parser.set_defaults(multichain_backbone=False) + parser.add_argument( + '--multichain-backbone', action='store_true', + help='use the backbones of all chains in the input for conditioning' + ) + parser.add_argument( + '--singlechain-backbone', dest='multichain_backbone', + action='store_false', + help='use the backbone of only target chain in the input for conditioning' + ) + parser.add_argument("--nogpu", action="store_true", help="Do not use GPU even if available") + + args = parser.parse_args() + + model, alphabet = esm.pretrained.esm_if1_gvp4_t16_142M_UR50() + model = model.eval() + + if args.multichain_backbone: + sample_seq_multichain(model, alphabet, args) + else: + sample_seq_singlechain(model, alphabet, args) + + +if __name__ == '__main__': + main() diff --git a/esm/source/examples/inverse_folding/score_log_likelihoods.py b/esm/source/examples/inverse_folding/score_log_likelihoods.py new file mode 100644 index 0000000000000000000000000000000000000000..cd81951dfb52885c4b4eed1e225fb1ad5d896cf7 --- /dev/null +++ b/esm/source/examples/inverse_folding/score_log_likelihoods.py @@ -0,0 +1,131 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. +# +# Scores sequences based on a given structure. +# +# usage: +# score_log_likelihoods.py [-h] [--outpath OUTPATH] [--chain CHAIN] pdbfile seqfile + +import argparse +from biotite.sequence.io.fasta import FastaFile, get_sequences +import numpy as np +from pathlib import Path +import torch +import torch.nn.functional as F +from tqdm import tqdm + +import esm +import esm.inverse_folding + + +def score_singlechain_backbone(model, alphabet, args): + if torch.cuda.is_available() and not args.nogpu: + model = model.cuda() + print("Transferred model to GPU") + coords, native_seq = esm.inverse_folding.util.load_coords(args.pdbfile, args.chain) + print('Native sequence loaded from structure file:') + print(native_seq) + print('\n') + + ll, _ = esm.inverse_folding.util.score_sequence( + model, alphabet, coords, native_seq) + print('Native sequence') + print(f'Log likelihood: {ll:.2f}') + print(f'Perplexity: {np.exp(-ll):.2f}') + + print('\nScoring variant sequences from sequence file..\n') + infile = FastaFile() + infile.read(args.seqfile) + seqs = get_sequences(infile) + Path(args.outpath).parent.mkdir(parents=True, exist_ok=True) + with open(args.outpath, 'w') as fout: + fout.write('seqid,log_likelihood\n') + for header, seq in tqdm(seqs.items()): + ll, _ = esm.inverse_folding.util.score_sequence( + model, alphabet, coords, str(seq)) + fout.write(header + ',' + str(ll) + '\n') + print(f'Results saved to {args.outpath}') + + +def score_multichain_backbone(model, alphabet, args): + if torch.cuda.is_available() and not args.nogpu: + model = model.cuda() + print("Transferred model to GPU") + structure = esm.inverse_folding.util.load_structure(args.pdbfile) + coords, native_seqs = esm.inverse_folding.multichain_util.extract_coords_from_complex(structure) + target_chain_id = args.chain + native_seq = native_seqs[target_chain_id] + print('Native sequence loaded from structure file:') + print(native_seq) + print('\n') + + ll, _ = esm.inverse_folding.multichain_util.score_sequence_in_complex( + model, alphabet, coords, target_chain_id, native_seq) + print('Native sequence') + print(f'Log likelihood: {ll:.2f}') + print(f'Perplexity: {np.exp(-ll):.2f}') + + print('\nScoring variant sequences from sequence file..\n') + infile = FastaFile() + infile.read(args.seqfile) + seqs = get_sequences(infile) + Path(args.outpath).parent.mkdir(parents=True, exist_ok=True) + with open(args.outpath, 'w') as fout: + fout.write('seqid,log_likelihood\n') + for header, seq in tqdm(seqs.items()): + ll, _ = esm.inverse_folding.multichain_util.score_sequence_in_complex( + model, alphabet, coords, target_chain_id, str(seq)) + fout.write(header + ',' + str(ll) + '\n') + print(f'Results saved to {args.outpath}') + + +def main(): + parser = argparse.ArgumentParser( + description='Score sequences based on a given structure.' + ) + parser.add_argument( + 'pdbfile', type=str, + help='input filepath, either .pdb or .cif', + ) + parser.add_argument( + 'seqfile', type=str, + help='input filepath for variant sequences in a .fasta file', + ) + parser.add_argument( + '--outpath', type=str, + help='output filepath for scores of variant sequences', + default='output/sequence_scores.csv', + ) + parser.add_argument( + '--chain', type=str, + help='chain id for the chain of interest', default='A', + ) + parser.set_defaults(multichain_backbone=False) + parser.add_argument( + '--multichain-backbone', action='store_true', + help='use the backbones of all chains in the input for conditioning' + ) + parser.add_argument( + '--singlechain-backbone', dest='multichain_backbone', + action='store_false', + help='use the backbone of only target chain in the input for conditioning' + ) + + parser.add_argument("--nogpu", action="store_true", help="Do not use GPU even if available") + + args = parser.parse_args() + + model, alphabet = esm.pretrained.esm_if1_gvp4_t16_142M_UR50() + model = model.eval() + + if args.multichain_backbone: + score_multichain_backbone(model, alphabet, args) + else: + score_singlechain_backbone(model, alphabet, args) + + + +if __name__ == '__main__': + main() diff --git a/esm/source/examples/lm-design/2N2U.pdb b/esm/source/examples/lm-design/2N2U.pdb new file mode 100644 index 0000000000000000000000000000000000000000..f020db5b59b54305ad309b9f6b69a5d2335abd98 --- /dev/null +++ b/esm/source/examples/lm-design/2N2U.pdb @@ -0,0 +1,1097 @@ +ATOM 1 N MET A 1 2.474 14.947 -3.252 1.00 30.41 N +ATOM 2 CA MET A 1 1.932 13.612 -3.600 1.00 73.02 C +ATOM 3 C MET A 1 3.047 12.685 -4.110 1.00 44.21 C +ATOM 4 O MET A 1 3.901 13.105 -4.899 1.00 12.21 O +ATOM 5 CB MET A 1 0.773 13.733 -4.632 1.00 52.11 C +ATOM 6 CG MET A 1 1.118 14.483 -5.932 1.00 63.25 C +ATOM 7 SD MET A 1 1.519 16.227 -5.649 1.00 2.52 S +ATOM 8 CE MET A 1 1.918 16.775 -7.309 1.00 22.41 C +ATOM 9 H1 MET A 1 2.965 15.360 -4.068 1.00 37.08 H +ATOM 10 H2 MET A 1 3.147 14.868 -2.462 1.00 37.08 H +ATOM 11 H3 MET A 1 1.703 15.583 -2.968 1.00 37.08 H +ATOM 12 HA MET A 1 1.530 13.192 -2.682 1.00 72.41 H +ATOM 13 HB2 MET A 1 0.434 12.737 -4.897 1.00 52.45 H +ATOM 14 HB3 MET A 1 -0.052 14.254 -4.158 1.00 31.25 H +ATOM 15 HG2 MET A 1 1.970 14.005 -6.396 1.00 43.45 H +ATOM 16 HG3 MET A 1 0.268 14.429 -6.602 1.00 1.42 H +ATOM 17 HE1 MET A 1 2.206 17.815 -7.285 1.00 41.41 H +ATOM 18 HE2 MET A 1 1.055 16.655 -7.948 1.00 32.23 H +ATOM 19 HE3 MET A 1 2.736 16.185 -7.696 1.00 20.43 H +ATOM 20 N VAL A 2 3.067 11.433 -3.594 1.00 71.32 N +ATOM 21 CA VAL A 2 3.984 10.371 -4.058 1.00 23.32 C +ATOM 22 C VAL A 2 3.155 9.215 -4.628 1.00 3.23 C +ATOM 23 O VAL A 2 2.230 8.734 -3.970 1.00 33.21 O +ATOM 24 CB VAL A 2 4.908 9.812 -2.913 1.00 71.22 C +ATOM 25 CG1 VAL A 2 5.958 8.822 -3.481 1.00 64.04 C +ATOM 26 CG2 VAL A 2 5.582 10.955 -2.132 1.00 73.43 C +ATOM 27 H VAL A 2 2.429 11.213 -2.887 1.00 65.22 H +ATOM 28 HA VAL A 2 4.624 10.780 -4.847 1.00 41.13 H +ATOM 29 HB VAL A 2 4.283 9.259 -2.212 1.00 20.22 H +ATOM 30 HG11 VAL A 2 5.456 7.995 -3.971 1.00 23.31 H +ATOM 31 HG12 VAL A 2 6.569 8.435 -2.677 1.00 10.15 H +ATOM 32 HG13 VAL A 2 6.592 9.329 -4.198 1.00 53.33 H +ATOM 33 HG21 VAL A 2 6.201 10.548 -1.340 1.00 5.25 H +ATOM 34 HG22 VAL A 2 4.824 11.594 -1.697 1.00 45.50 H +ATOM 35 HG23 VAL A 2 6.199 11.542 -2.796 1.00 23.40 H +ATOM 36 N ASP A 3 3.465 8.809 -5.854 1.00 62.11 N +ATOM 37 CA ASP A 3 2.839 7.650 -6.508 1.00 12.32 C +ATOM 38 C ASP A 3 3.379 6.341 -5.886 1.00 32.51 C +ATOM 39 O ASP A 3 4.588 6.101 -5.921 1.00 24.12 O +ATOM 40 CB ASP A 3 3.148 7.741 -8.023 1.00 21.11 C +ATOM 41 CG ASP A 3 2.627 6.567 -8.863 1.00 53.15 C +ATOM 42 OD1 ASP A 3 3.349 5.554 -9.016 1.00 24.42 O +ATOM 43 OD2 ASP A 3 1.497 6.657 -9.390 1.00 41.22 O +ATOM 44 H ASP A 3 4.146 9.306 -6.356 1.00 60.51 H +ATOM 45 HA ASP A 3 1.763 7.711 -6.357 1.00 32.14 H +ATOM 46 HB2 ASP A 3 2.713 8.658 -8.412 1.00 1.32 H +ATOM 47 HB3 ASP A 3 4.226 7.807 -8.153 1.00 74.35 H +ATOM 48 N LEU A 4 2.487 5.533 -5.269 1.00 15.15 N +ATOM 49 CA LEU A 4 2.843 4.213 -4.688 1.00 52.22 C +ATOM 50 C LEU A 4 1.925 3.124 -5.275 1.00 20.20 C +ATOM 51 O LEU A 4 0.745 3.063 -4.956 1.00 2.34 O +ATOM 52 CB LEU A 4 2.705 4.235 -3.130 1.00 42.51 C +ATOM 53 CG LEU A 4 3.628 5.220 -2.347 1.00 71.31 C +ATOM 54 CD1 LEU A 4 3.306 5.178 -0.839 1.00 12.10 C +ATOM 55 CD2 LEU A 4 5.122 4.915 -2.605 1.00 43.25 C +ATOM 56 H LEU A 4 1.557 5.831 -5.200 1.00 11.54 H +ATOM 57 HA LEU A 4 3.877 3.979 -4.948 1.00 72.02 H +ATOM 58 HB2 LEU A 4 1.672 4.482 -2.888 1.00 2.21 H +ATOM 59 HB3 LEU A 4 2.897 3.231 -2.758 1.00 65.12 H +ATOM 60 HG LEU A 4 3.437 6.232 -2.692 1.00 52.31 H +ATOM 61 HD11 LEU A 4 3.469 4.177 -0.450 1.00 11.44 H +ATOM 62 HD12 LEU A 4 2.273 5.456 -0.681 1.00 74.44 H +ATOM 63 HD13 LEU A 4 3.940 5.874 -0.311 1.00 62.15 H +ATOM 64 HD21 LEU A 4 5.740 5.610 -2.048 1.00 44.31 H +ATOM 65 HD22 LEU A 4 5.335 5.021 -3.660 1.00 45.10 H +ATOM 66 HD23 LEU A 4 5.353 3.903 -2.294 1.00 1.24 H +ATOM 67 N LYS A 5 2.479 2.249 -6.118 1.00 33.01 N +ATOM 68 CA LYS A 5 1.733 1.121 -6.723 1.00 52.12 C +ATOM 69 C LYS A 5 2.309 -0.189 -6.172 1.00 21.32 C +ATOM 70 O LYS A 5 3.433 -0.552 -6.482 1.00 2.13 O +ATOM 71 CB LYS A 5 1.777 1.158 -8.294 1.00 71.43 C +ATOM 72 CG LYS A 5 0.620 1.929 -8.994 1.00 75.12 C +ATOM 73 CD LYS A 5 0.636 3.474 -8.780 1.00 64.51 C +ATOM 74 CE LYS A 5 -0.427 3.981 -7.799 1.00 65.12 C +ATOM 75 NZ LYS A 5 -0.444 5.466 -7.668 1.00 45.31 N +ATOM 76 H LYS A 5 3.436 2.355 -6.296 1.00 43.13 H +ATOM 77 HA LYS A 5 0.690 1.191 -6.403 1.00 52.03 H +ATOM 78 HB2 LYS A 5 2.711 1.616 -8.611 1.00 61.01 H +ATOM 79 HB3 LYS A 5 1.767 0.139 -8.672 1.00 44.23 H +ATOM 80 HG2 LYS A 5 0.681 1.729 -10.061 1.00 3.42 H +ATOM 81 HG3 LYS A 5 -0.322 1.524 -8.629 1.00 2.31 H +ATOM 82 HD2 LYS A 5 1.609 3.774 -8.410 1.00 52.03 H +ATOM 83 HD3 LYS A 5 0.473 3.960 -9.740 1.00 74.51 H +ATOM 84 HE2 LYS A 5 -1.400 3.662 -8.146 1.00 13.31 H +ATOM 85 HE3 LYS A 5 -0.242 3.548 -6.825 1.00 24.14 H +ATOM 86 HZ1 LYS A 5 -0.765 5.897 -8.560 1.00 73.55 H +ATOM 87 HZ2 LYS A 5 0.508 5.818 -7.452 1.00 1.14 H +ATOM 88 HZ3 LYS A 5 -1.092 5.758 -6.904 1.00 34.01 H +ATOM 89 N ILE A 6 1.508 -0.925 -5.391 1.00 42.42 N +ATOM 90 CA ILE A 6 1.982 -2.110 -4.672 1.00 44.20 C +ATOM 91 C ILE A 6 1.521 -3.337 -5.458 1.00 1.55 C +ATOM 92 O ILE A 6 0.322 -3.563 -5.585 1.00 63.22 O +ATOM 93 CB ILE A 6 1.437 -2.212 -3.183 1.00 21.25 C +ATOM 94 CG1 ILE A 6 1.885 -0.992 -2.299 1.00 53.53 C +ATOM 95 CG2 ILE A 6 1.885 -3.554 -2.533 1.00 0.14 C +ATOM 96 CD1 ILE A 6 1.127 0.312 -2.533 1.00 62.52 C +ATOM 97 H ILE A 6 0.548 -0.767 -5.418 1.00 60.40 H +ATOM 98 HA ILE A 6 3.074 -2.096 -4.636 1.00 31.21 H +ATOM 99 HB ILE A 6 0.347 -2.223 -3.229 1.00 54.54 H +ATOM 100 HG12 ILE A 6 1.759 -1.240 -1.253 1.00 22.21 H +ATOM 101 HG13 ILE A 6 2.937 -0.792 -2.476 1.00 74.14 H +ATOM 102 HG21 ILE A 6 1.518 -4.393 -3.116 1.00 62.25 H +ATOM 103 HG22 ILE A 6 1.487 -3.631 -1.529 1.00 60.52 H +ATOM 104 HG23 ILE A 6 2.968 -3.604 -2.485 1.00 32.31 H +ATOM 105 HD11 ILE A 6 1.250 0.624 -3.559 1.00 31.12 H +ATOM 106 HD12 ILE A 6 1.519 1.076 -1.876 1.00 43.43 H +ATOM 107 HD13 ILE A 6 0.077 0.164 -2.322 1.00 32.31 H +ATOM 108 N ASP A 7 2.475 -4.116 -5.981 1.00 2.13 N +ATOM 109 CA ASP A 7 2.172 -5.409 -6.621 1.00 30.20 C +ATOM 110 C ASP A 7 1.508 -6.318 -5.581 1.00 3.24 C +ATOM 111 O ASP A 7 1.975 -6.355 -4.452 1.00 23.12 O +ATOM 112 CB ASP A 7 3.472 -6.077 -7.130 1.00 61.23 C +ATOM 113 CG ASP A 7 3.248 -7.504 -7.682 1.00 13.42 C +ATOM 114 OD1 ASP A 7 2.788 -7.630 -8.836 1.00 75.25 O +ATOM 115 OD2 ASP A 7 3.526 -8.503 -6.966 1.00 51.34 O +ATOM 116 H ASP A 7 3.407 -3.836 -5.872 1.00 71.34 H +ATOM 117 HA ASP A 7 1.488 -5.235 -7.454 1.00 62.23 H +ATOM 118 HB2 ASP A 7 3.897 -5.463 -7.919 1.00 53.33 H +ATOM 119 HB3 ASP A 7 4.190 -6.123 -6.316 1.00 25.45 H +ATOM 120 N VAL A 8 0.441 -7.046 -5.953 1.00 71.44 N +ATOM 121 CA VAL A 8 -0.200 -8.042 -5.055 1.00 35.32 C +ATOM 122 C VAL A 8 -0.354 -9.369 -5.815 1.00 11.50 C +ATOM 123 O VAL A 8 -0.940 -9.418 -6.906 1.00 54.22 O +ATOM 124 CB VAL A 8 -1.586 -7.568 -4.451 1.00 1.23 C +ATOM 125 CG1 VAL A 8 -1.386 -6.367 -3.506 1.00 1.31 C +ATOM 126 CG2 VAL A 8 -2.646 -7.245 -5.532 1.00 62.52 C +ATOM 127 H VAL A 8 0.105 -6.994 -6.871 1.00 20.22 H +ATOM 128 HA VAL A 8 0.480 -8.220 -4.214 1.00 13.10 H +ATOM 129 HB VAL A 8 -1.972 -8.388 -3.844 1.00 23.15 H +ATOM 130 HG11 VAL A 8 -0.980 -5.527 -4.057 1.00 14.13 H +ATOM 131 HG12 VAL A 8 -0.698 -6.640 -2.715 1.00 13.42 H +ATOM 132 HG13 VAL A 8 -2.335 -6.085 -3.066 1.00 12.11 H +ATOM 133 HG21 VAL A 8 -3.584 -6.966 -5.062 1.00 2.41 H +ATOM 134 HG22 VAL A 8 -2.808 -8.118 -6.151 1.00 51.44 H +ATOM 135 HG23 VAL A 8 -2.304 -6.429 -6.154 1.00 14.32 H +ATOM 136 N SER A 9 0.221 -10.441 -5.243 1.00 31.44 N +ATOM 137 CA SER A 9 0.249 -11.784 -5.857 1.00 3.51 C +ATOM 138 C SER A 9 -0.835 -12.705 -5.265 1.00 1.10 C +ATOM 139 O SER A 9 -1.115 -13.781 -5.806 1.00 55.42 O +ATOM 140 CB SER A 9 1.653 -12.401 -5.671 1.00 25.52 C +ATOM 141 OG SER A 9 2.659 -11.532 -6.175 1.00 20.22 O +ATOM 142 H SER A 9 0.659 -10.304 -4.372 1.00 63.32 H +ATOM 143 HA SER A 9 0.058 -11.678 -6.922 1.00 51.45 H +ATOM 144 HB2 SER A 9 1.845 -12.572 -4.620 1.00 33.14 H +ATOM 145 HB3 SER A 9 1.716 -13.341 -6.208 1.00 44.33 H +ATOM 146 HG SER A 9 2.246 -10.793 -6.640 1.00 63.31 H +ATOM 147 N ASP A 10 -1.447 -12.261 -4.157 1.00 12.02 N +ATOM 148 CA ASP A 10 -2.502 -13.005 -3.449 1.00 74.03 C +ATOM 149 C ASP A 10 -3.614 -12.029 -3.007 1.00 13.33 C +ATOM 150 O ASP A 10 -3.389 -10.814 -2.911 1.00 63.25 O +ATOM 151 CB ASP A 10 -1.878 -13.789 -2.254 1.00 62.50 C +ATOM 152 CG ASP A 10 -2.908 -14.381 -1.272 1.00 63.35 C +ATOM 153 OD1 ASP A 10 -3.614 -15.343 -1.640 1.00 54.33 O +ATOM 154 OD2 ASP A 10 -3.041 -13.865 -0.144 1.00 62.42 O +ATOM 155 H ASP A 10 -1.189 -11.383 -3.804 1.00 30.43 H +ATOM 156 HA ASP A 10 -2.938 -13.720 -4.148 1.00 23.24 H +ATOM 157 HB2 ASP A 10 -1.287 -14.610 -2.648 1.00 12.43 H +ATOM 158 HB3 ASP A 10 -1.213 -13.129 -1.708 1.00 40.23 H +ATOM 159 N ASP A 11 -4.802 -12.589 -2.744 1.00 33.51 N +ATOM 160 CA ASP A 11 -6.028 -11.833 -2.425 1.00 52.32 C +ATOM 161 C ASP A 11 -6.032 -11.379 -0.952 1.00 74.13 C +ATOM 162 O ASP A 11 -6.364 -10.229 -0.651 1.00 43.11 O +ATOM 163 CB ASP A 11 -7.252 -12.743 -2.703 1.00 64.53 C +ATOM 164 CG ASP A 11 -8.607 -12.023 -2.569 1.00 61.24 C +ATOM 165 OD1 ASP A 11 -9.125 -11.885 -1.439 1.00 4.12 O +ATOM 166 OD2 ASP A 11 -9.166 -11.588 -3.601 1.00 72.22 O +ATOM 167 H ASP A 11 -4.853 -13.567 -2.736 1.00 71.11 H +ATOM 168 HA ASP A 11 -6.076 -10.960 -3.072 1.00 40.31 H +ATOM 169 HB2 ASP A 11 -7.167 -13.135 -3.714 1.00 24.24 H +ATOM 170 HB3 ASP A 11 -7.235 -13.583 -2.015 1.00 23.23 H +ATOM 171 N GLU A 12 -5.684 -12.310 -0.044 1.00 42.20 N +ATOM 172 CA GLU A 12 -5.738 -12.075 1.408 1.00 4.23 C +ATOM 173 C GLU A 12 -4.698 -11.021 1.842 1.00 23.45 C +ATOM 174 O GLU A 12 -4.999 -10.157 2.673 1.00 71.33 O +ATOM 175 CB GLU A 12 -5.527 -13.406 2.172 1.00 52.30 C +ATOM 176 CG GLU A 12 -5.441 -13.279 3.714 1.00 44.12 C +ATOM 177 CD GLU A 12 -6.738 -12.781 4.389 1.00 12.52 C +ATOM 178 OE1 GLU A 12 -6.916 -11.550 4.560 1.00 71.42 O +ATOM 179 OE2 GLU A 12 -7.580 -13.624 4.770 1.00 31.21 O +ATOM 180 H GLU A 12 -5.373 -13.186 -0.364 1.00 43.22 H +ATOM 181 HA GLU A 12 -6.731 -11.694 1.642 1.00 45.14 H +ATOM 182 HB2 GLU A 12 -6.346 -14.079 1.931 1.00 53.25 H +ATOM 183 HB3 GLU A 12 -4.605 -13.855 1.819 1.00 30.11 H +ATOM 184 HG2 GLU A 12 -5.191 -14.254 4.123 1.00 32.02 H +ATOM 185 HG3 GLU A 12 -4.634 -12.593 3.959 1.00 43.10 H +ATOM 186 N GLU A 13 -3.469 -11.095 1.286 1.00 35.32 N +ATOM 187 CA GLU A 13 -2.432 -10.101 1.579 1.00 43.00 C +ATOM 188 C GLU A 13 -2.853 -8.726 1.026 1.00 63.02 C +ATOM 189 O GLU A 13 -2.596 -7.721 1.661 1.00 25.12 O +ATOM 190 CB GLU A 13 -1.051 -10.557 1.037 1.00 73.11 C +ATOM 191 CG GLU A 13 -0.954 -10.760 -0.499 1.00 73.42 C +ATOM 192 CD GLU A 13 -0.235 -9.643 -1.282 1.00 40.23 C +ATOM 193 OE1 GLU A 13 -0.465 -8.450 -1.002 1.00 45.44 O +ATOM 194 OE2 GLU A 13 0.561 -9.953 -2.201 1.00 23.34 O +ATOM 195 H GLU A 13 -3.259 -11.827 0.668 1.00 40.33 H +ATOM 196 HA GLU A 13 -2.365 -10.024 2.664 1.00 75.41 H +ATOM 197 HB2 GLU A 13 -0.314 -9.831 1.332 1.00 34.53 H +ATOM 198 HB3 GLU A 13 -0.798 -11.498 1.521 1.00 54.54 H +ATOM 199 HG2 GLU A 13 -0.433 -11.687 -0.678 1.00 54.13 H +ATOM 200 HG3 GLU A 13 -1.960 -10.855 -0.895 1.00 31.11 H +ATOM 201 N ALA A 14 -3.546 -8.720 -0.139 1.00 2.41 N +ATOM 202 CA ALA A 14 -4.075 -7.490 -0.762 1.00 62.50 C +ATOM 203 C ALA A 14 -5.079 -6.798 0.179 1.00 71.44 C +ATOM 204 O ALA A 14 -5.050 -5.575 0.334 1.00 74.25 O +ATOM 205 CB ALA A 14 -4.719 -7.814 -2.121 1.00 22.14 C +ATOM 206 H ALA A 14 -3.704 -9.573 -0.591 1.00 54.43 H +ATOM 207 HA ALA A 14 -3.235 -6.825 -0.936 1.00 2.31 H +ATOM 208 HB1 ALA A 14 -5.567 -8.474 -1.980 1.00 12.52 H +ATOM 209 HB2 ALA A 14 -3.991 -8.306 -2.755 1.00 55.25 H +ATOM 210 HB3 ALA A 14 -5.049 -6.903 -2.601 1.00 22.43 H +ATOM 211 N GLU A 15 -5.951 -7.616 0.800 1.00 21.43 N +ATOM 212 CA GLU A 15 -6.872 -7.180 1.865 1.00 74.13 C +ATOM 213 C GLU A 15 -6.100 -6.538 3.029 1.00 51.21 C +ATOM 214 O GLU A 15 -6.437 -5.442 3.479 1.00 41.42 O +ATOM 215 CB GLU A 15 -7.716 -8.388 2.367 1.00 3.30 C +ATOM 216 CG GLU A 15 -8.744 -8.931 1.351 1.00 73.52 C +ATOM 217 CD GLU A 15 -9.913 -7.962 1.099 1.00 73.21 C +ATOM 218 OE1 GLU A 15 -9.749 -7.008 0.315 1.00 4.53 O +ATOM 219 OE2 GLU A 15 -11.002 -8.142 1.692 1.00 72.14 O +ATOM 220 H GLU A 15 -5.995 -8.550 0.504 1.00 3.44 H +ATOM 221 HA GLU A 15 -7.539 -6.441 1.432 1.00 21.45 H +ATOM 222 HB2 GLU A 15 -7.037 -9.198 2.619 1.00 12.42 H +ATOM 223 HB3 GLU A 15 -8.249 -8.101 3.269 1.00 1.00 H +ATOM 224 HG2 GLU A 15 -8.237 -9.121 0.411 1.00 40.25 H +ATOM 225 HG3 GLU A 15 -9.137 -9.871 1.728 1.00 2.34 H +ATOM 226 N LYS A 16 -5.029 -7.228 3.460 1.00 54.51 N +ATOM 227 CA LYS A 16 -4.157 -6.778 4.556 1.00 63.12 C +ATOM 228 C LYS A 16 -3.437 -5.448 4.208 1.00 45.32 C +ATOM 229 O LYS A 16 -3.196 -4.637 5.100 1.00 43.35 O +ATOM 230 CB LYS A 16 -3.128 -7.890 4.903 1.00 55.32 C +ATOM 231 CG LYS A 16 -3.723 -9.163 5.562 1.00 13.32 C +ATOM 232 CD LYS A 16 -4.211 -8.909 7.007 1.00 13.45 C +ATOM 233 CE LYS A 16 -4.723 -10.182 7.712 1.00 60.32 C +ATOM 234 NZ LYS A 16 -5.992 -10.689 7.117 1.00 73.24 N +ATOM 235 H LYS A 16 -4.818 -8.075 3.017 1.00 23.35 H +ATOM 236 HA LYS A 16 -4.791 -6.611 5.423 1.00 71.15 H +ATOM 237 HB2 LYS A 16 -2.622 -8.193 3.990 1.00 2.40 H +ATOM 238 HB3 LYS A 16 -2.382 -7.480 5.580 1.00 24.21 H +ATOM 239 HG2 LYS A 16 -4.562 -9.504 4.965 1.00 35.23 H +ATOM 240 HG3 LYS A 16 -2.963 -9.937 5.577 1.00 63.00 H +ATOM 241 HD2 LYS A 16 -3.388 -8.501 7.586 1.00 11.31 H +ATOM 242 HD3 LYS A 16 -5.015 -8.181 6.982 1.00 71.33 H +ATOM 243 HE2 LYS A 16 -3.969 -10.960 7.646 1.00 15.41 H +ATOM 244 HE3 LYS A 16 -4.899 -9.953 8.756 1.00 21.34 H +ATOM 245 HZ1 LYS A 16 -5.860 -10.893 6.104 1.00 31.43 H +ATOM 246 HZ2 LYS A 16 -6.743 -9.975 7.215 1.00 62.11 H +ATOM 247 HZ3 LYS A 16 -6.301 -11.563 7.593 1.00 74.25 H +ATOM 248 N ILE A 17 -3.125 -5.215 2.905 1.00 11.51 N +ATOM 249 CA ILE A 17 -2.508 -3.940 2.453 1.00 2.23 C +ATOM 250 C ILE A 17 -3.501 -2.790 2.711 1.00 62.42 C +ATOM 251 O ILE A 17 -3.157 -1.779 3.319 1.00 12.05 O +ATOM 252 CB ILE A 17 -2.106 -3.932 0.915 1.00 21.13 C +ATOM 253 CG1 ILE A 17 -1.297 -5.207 0.493 1.00 44.00 C +ATOM 254 CG2 ILE A 17 -1.327 -2.642 0.549 1.00 53.42 C +ATOM 255 CD1 ILE A 17 -0.133 -5.611 1.393 1.00 50.12 C +ATOM 256 H ILE A 17 -3.317 -5.910 2.245 1.00 54.41 H +ATOM 257 HA ILE A 17 -1.609 -3.781 3.048 1.00 71.41 H +ATOM 258 HB ILE A 17 -3.035 -3.919 0.337 1.00 40.23 H +ATOM 259 HG12 ILE A 17 -1.971 -6.048 0.465 1.00 40.03 H +ATOM 260 HG13 ILE A 17 -0.897 -5.065 -0.507 1.00 60.43 H +ATOM 261 HG21 ILE A 17 -0.415 -2.588 1.130 1.00 0.11 H +ATOM 262 HG22 ILE A 17 -1.936 -1.770 0.761 1.00 55.24 H +ATOM 263 HG23 ILE A 17 -1.079 -2.650 -0.505 1.00 45.23 H +ATOM 264 HD11 ILE A 17 0.288 -6.546 1.021 1.00 72.31 H +ATOM 265 HD12 ILE A 17 -0.481 -5.763 2.405 1.00 61.41 H +ATOM 266 HD13 ILE A 17 0.628 -4.846 1.379 1.00 20.43 H +ATOM 267 N ILE A 18 -4.760 -3.023 2.292 1.00 60.15 N +ATOM 268 CA ILE A 18 -5.864 -2.051 2.402 1.00 60.01 C +ATOM 269 C ILE A 18 -6.120 -1.683 3.875 1.00 55.43 C +ATOM 270 O ILE A 18 -6.245 -0.511 4.211 1.00 1.03 O +ATOM 271 CB ILE A 18 -7.184 -2.638 1.773 1.00 61.24 C +ATOM 272 CG1 ILE A 18 -6.958 -3.052 0.289 1.00 22.34 C +ATOM 273 CG2 ILE A 18 -8.376 -1.652 1.888 1.00 44.12 C +ATOM 274 CD1 ILE A 18 -8.124 -3.783 -0.333 1.00 64.32 C +ATOM 275 H ILE A 18 -4.955 -3.902 1.904 1.00 30.12 H +ATOM 276 HA ILE A 18 -5.580 -1.159 1.846 1.00 11.43 H +ATOM 277 HB ILE A 18 -7.446 -3.532 2.338 1.00 23.42 H +ATOM 278 HG12 ILE A 18 -6.771 -2.170 -0.308 1.00 25.05 H +ATOM 279 HG13 ILE A 18 -6.095 -3.703 0.225 1.00 30.32 H +ATOM 280 HG21 ILE A 18 -8.152 -0.739 1.354 1.00 31.55 H +ATOM 281 HG22 ILE A 18 -8.561 -1.420 2.929 1.00 4.35 H +ATOM 282 HG23 ILE A 18 -9.267 -2.105 1.467 1.00 42.42 H +ATOM 283 HD11 ILE A 18 -8.990 -3.132 -0.363 1.00 34.51 H +ATOM 284 HD12 ILE A 18 -8.357 -4.664 0.250 1.00 31.22 H +ATOM 285 HD13 ILE A 18 -7.865 -4.077 -1.337 1.00 70.44 H +ATOM 286 N ARG A 19 -6.151 -2.714 4.747 1.00 43.22 N +ATOM 287 CA ARG A 19 -6.472 -2.541 6.177 1.00 52.04 C +ATOM 288 C ARG A 19 -5.353 -1.766 6.893 1.00 61.44 C +ATOM 289 O ARG A 19 -5.620 -0.763 7.559 1.00 3.50 O +ATOM 290 CB ARG A 19 -6.729 -3.913 6.878 1.00 51.24 C +ATOM 291 CG ARG A 19 -7.837 -4.791 6.239 1.00 32.32 C +ATOM 292 CD ARG A 19 -9.165 -4.039 5.999 1.00 72.11 C +ATOM 293 NE ARG A 19 -10.196 -4.893 5.377 1.00 44.14 N +ATOM 294 CZ ARG A 19 -10.253 -5.236 4.077 1.00 1.24 C +ATOM 295 NH1 ARG A 19 -9.337 -4.819 3.206 1.00 13.53 N +ATOM 296 NH2 ARG A 19 -11.255 -5.977 3.650 1.00 50.30 N +ATOM 297 H ARG A 19 -5.936 -3.613 4.418 1.00 23.24 H +ATOM 298 HA ARG A 19 -7.388 -1.953 6.232 1.00 33.25 H +ATOM 299 HB2 ARG A 19 -5.806 -4.489 6.871 1.00 43.41 H +ATOM 300 HB3 ARG A 19 -7.004 -3.730 7.913 1.00 33.02 H +ATOM 301 HG2 ARG A 19 -7.479 -5.157 5.288 1.00 53.32 H +ATOM 302 HG3 ARG A 19 -8.030 -5.638 6.889 1.00 61.13 H +ATOM 303 HD2 ARG A 19 -9.545 -3.683 6.947 1.00 54.53 H +ATOM 304 HD3 ARG A 19 -8.979 -3.187 5.352 1.00 50.54 H +ATOM 305 HE ARG A 19 -10.897 -5.245 5.976 1.00 14.33 H +ATOM 306 HH11 ARG A 19 -8.578 -4.241 3.514 1.00 34.14 H +ATOM 307 HH12 ARG A 19 -9.399 -5.088 2.242 1.00 10.10 H +ATOM 308 HH21 ARG A 19 -11.966 -6.285 4.296 1.00 41.03 H +ATOM 309 HH22 ARG A 19 -11.315 -6.244 2.682 1.00 5.31 H +ATOM 310 N GLU A 20 -4.100 -2.217 6.702 1.00 23.34 N +ATOM 311 CA GLU A 20 -2.920 -1.640 7.370 1.00 24.43 C +ATOM 312 C GLU A 20 -2.602 -0.201 6.893 1.00 41.24 C +ATOM 313 O GLU A 20 -1.964 0.566 7.634 1.00 75.02 O +ATOM 314 CB GLU A 20 -1.681 -2.582 7.220 1.00 53.21 C +ATOM 315 CG GLU A 20 -1.576 -3.708 8.287 1.00 71.03 C +ATOM 316 CD GLU A 20 -2.665 -4.809 8.209 1.00 74.24 C +ATOM 317 OE1 GLU A 20 -3.795 -4.599 8.700 1.00 13.02 O +ATOM 318 OE2 GLU A 20 -2.373 -5.911 7.687 1.00 10.11 O +ATOM 319 H GLU A 20 -3.962 -2.977 6.100 1.00 54.31 H +ATOM 320 HA GLU A 20 -3.169 -1.575 8.429 1.00 14.13 H +ATOM 321 HB2 GLU A 20 -1.716 -3.049 6.241 1.00 52.41 H +ATOM 322 HB3 GLU A 20 -0.774 -1.986 7.276 1.00 62.25 H +ATOM 323 HG2 GLU A 20 -0.605 -4.176 8.185 1.00 1.20 H +ATOM 324 HG3 GLU A 20 -1.627 -3.251 9.274 1.00 13.12 H +ATOM 325 N ILE A 21 -3.036 0.163 5.672 1.00 72.23 N +ATOM 326 CA ILE A 21 -2.911 1.546 5.171 1.00 12.44 C +ATOM 327 C ILE A 21 -4.061 2.410 5.725 1.00 34.33 C +ATOM 328 O ILE A 21 -3.825 3.424 6.381 1.00 75.54 O +ATOM 329 CB ILE A 21 -2.878 1.618 3.591 1.00 14.15 C +ATOM 330 CG1 ILE A 21 -1.610 0.900 3.022 1.00 53.24 C +ATOM 331 CG2 ILE A 21 -2.943 3.079 3.075 1.00 61.34 C +ATOM 332 CD1 ILE A 21 -0.280 1.494 3.461 1.00 62.11 C +ATOM 333 H ILE A 21 -3.441 -0.519 5.090 1.00 13.51 H +ATOM 334 HA ILE A 21 -1.968 1.952 5.544 1.00 63.44 H +ATOM 335 HB ILE A 21 -3.760 1.102 3.222 1.00 51.15 H +ATOM 336 HG12 ILE A 21 -1.621 -0.133 3.336 1.00 32.44 H +ATOM 337 HG13 ILE A 21 -1.641 0.930 1.937 1.00 40.44 H +ATOM 338 HG21 ILE A 21 -2.897 3.085 1.990 1.00 64.23 H +ATOM 339 HG22 ILE A 21 -2.111 3.646 3.468 1.00 54.23 H +ATOM 340 HG23 ILE A 21 -3.871 3.539 3.390 1.00 15.13 H +ATOM 341 HD11 ILE A 21 -0.203 1.466 4.540 1.00 52.12 H +ATOM 342 HD12 ILE A 21 -0.200 2.518 3.120 1.00 3.53 H +ATOM 343 HD13 ILE A 21 0.526 0.915 3.035 1.00 64.30 H +ATOM 344 N ARG A 22 -5.305 1.956 5.530 1.00 74.01 N +ATOM 345 CA ARG A 22 -6.502 2.791 5.768 1.00 43.31 C +ATOM 346 C ARG A 22 -6.832 2.948 7.264 1.00 3.03 C +ATOM 347 O ARG A 22 -7.630 3.825 7.625 1.00 42.33 O +ATOM 348 CB ARG A 22 -7.730 2.263 4.984 1.00 51.13 C +ATOM 349 CG ARG A 22 -7.568 2.347 3.450 1.00 62.31 C +ATOM 350 CD ARG A 22 -8.865 2.025 2.680 1.00 0.34 C +ATOM 351 NE ARG A 22 -9.998 2.906 3.043 1.00 11.23 N +ATOM 352 CZ ARG A 22 -10.090 4.226 2.774 1.00 32.20 C +ATOM 353 NH1 ARG A 22 -9.119 4.881 2.138 1.00 33.44 N +ATOM 354 NH2 ARG A 22 -11.181 4.886 3.137 1.00 52.24 N +ATOM 355 H ARG A 22 -5.422 1.016 5.285 1.00 40.10 H +ATOM 356 HA ARG A 22 -6.271 3.786 5.387 1.00 35.35 H +ATOM 357 HB2 ARG A 22 -7.902 1.224 5.254 1.00 24.30 H +ATOM 358 HB3 ARG A 22 -8.605 2.843 5.266 1.00 4.42 H +ATOM 359 HG2 ARG A 22 -7.251 3.351 3.181 1.00 62.04 H +ATOM 360 HG3 ARG A 22 -6.800 1.645 3.145 1.00 22.20 H +ATOM 361 HD2 ARG A 22 -8.675 2.123 1.617 1.00 33.54 H +ATOM 362 HD3 ARG A 22 -9.148 0.999 2.889 1.00 21.41 H +ATOM 363 HE ARG A 22 -10.748 2.478 3.512 1.00 43.33 H +ATOM 364 HH11 ARG A 22 -8.295 4.396 1.836 1.00 71.33 H +ATOM 365 HH12 ARG A 22 -9.211 5.861 1.948 1.00 55.20 H +ATOM 366 HH21 ARG A 22 -11.928 4.408 3.609 1.00 55.21 H +ATOM 367 HH22 ARG A 22 -11.264 5.870 2.948 1.00 21.54 H +ATOM 368 N GLU A 23 -6.230 2.107 8.131 1.00 50.31 N +ATOM 369 CA GLU A 23 -6.429 2.204 9.594 1.00 65.11 C +ATOM 370 C GLU A 23 -5.741 3.477 10.136 1.00 10.42 C +ATOM 371 O GLU A 23 -6.207 4.083 11.103 1.00 60.14 O +ATOM 372 CB GLU A 23 -5.892 0.938 10.332 1.00 11.42 C +ATOM 373 CG GLU A 23 -4.357 0.754 10.286 1.00 4.14 C +ATOM 374 CD GLU A 23 -3.850 -0.365 11.209 1.00 42.35 C +ATOM 375 OE1 GLU A 23 -3.853 -0.169 12.445 1.00 40.53 O +ATOM 376 OE2 GLU A 23 -3.436 -1.434 10.716 1.00 75.44 O +ATOM 377 H GLU A 23 -5.623 1.417 7.784 1.00 64.21 H +ATOM 378 HA GLU A 23 -7.501 2.286 9.773 1.00 71.43 H +ATOM 379 HB2 GLU A 23 -6.201 0.984 11.371 1.00 3.12 H +ATOM 380 HB3 GLU A 23 -6.348 0.064 9.879 1.00 4.11 H +ATOM 381 HG2 GLU A 23 -4.065 0.535 9.263 1.00 73.33 H +ATOM 382 HG3 GLU A 23 -3.888 1.686 10.584 1.00 22.14 H +ATOM 383 N GLN A 24 -4.618 3.860 9.497 1.00 33.32 N +ATOM 384 CA GLN A 24 -3.841 5.060 9.854 1.00 43.12 C +ATOM 385 C GLN A 24 -4.263 6.242 8.970 1.00 25.24 C +ATOM 386 O GLN A 24 -4.415 7.367 9.451 1.00 64.05 O +ATOM 387 CB GLN A 24 -2.322 4.780 9.683 1.00 70.05 C +ATOM 388 CG GLN A 24 -1.800 3.563 10.473 1.00 31.51 C +ATOM 389 CD GLN A 24 -0.316 3.265 10.244 1.00 54.12 C +ATOM 390 OE1 GLN A 24 0.485 4.167 10.008 1.00 3.23 O +ATOM 391 NE2 GLN A 24 0.062 2.007 10.313 1.00 35.05 N +ATOM 392 H GLN A 24 -4.283 3.304 8.763 1.00 13.22 H +ATOM 393 HA GLN A 24 -4.042 5.303 10.897 1.00 23.31 H +ATOM 394 HB2 GLN A 24 -2.110 4.613 8.626 1.00 74.53 H +ATOM 395 HB3 GLN A 24 -1.767 5.658 10.005 1.00 65.24 H +ATOM 396 HG2 GLN A 24 -1.950 3.743 11.533 1.00 4.33 H +ATOM 397 HG3 GLN A 24 -2.378 2.692 10.182 1.00 13.25 H +ATOM 398 HE21 GLN A 24 -0.617 1.328 10.511 1.00 13.15 H +ATOM 399 HE22 GLN A 24 1.006 1.794 10.153 1.00 55.44 H +ATOM 400 N TRP A 25 -4.446 5.969 7.664 1.00 5.10 N +ATOM 401 CA TRP A 25 -4.756 6.993 6.647 1.00 2.31 C +ATOM 402 C TRP A 25 -6.103 6.666 5.952 1.00 51.24 C +ATOM 403 O TRP A 25 -6.118 5.968 4.930 1.00 24.15 O +ATOM 404 CB TRP A 25 -3.619 7.074 5.589 1.00 0.41 C +ATOM 405 CG TRP A 25 -2.235 7.233 6.173 1.00 33.05 C +ATOM 406 CD1 TRP A 25 -1.674 8.371 6.673 1.00 12.13 C +ATOM 407 CD2 TRP A 25 -1.238 6.203 6.314 1.00 55.20 C +ATOM 408 NE1 TRP A 25 -0.415 8.104 7.140 1.00 64.34 N +ATOM 409 CE2 TRP A 25 -0.121 6.789 6.918 1.00 14.22 C +ATOM 410 CE3 TRP A 25 -1.186 4.843 5.983 1.00 25.44 C +ATOM 411 CZ2 TRP A 25 1.026 6.068 7.207 1.00 21.30 C +ATOM 412 CZ3 TRP A 25 -0.046 4.126 6.269 1.00 23.11 C +ATOM 413 CH2 TRP A 25 1.050 4.741 6.874 1.00 3.42 C +ATOM 414 H TRP A 25 -4.370 5.043 7.369 1.00 35.23 H +ATOM 415 HA TRP A 25 -4.847 7.960 7.138 1.00 34.21 H +ATOM 416 HB2 TRP A 25 -3.622 6.167 4.993 1.00 5.35 H +ATOM 417 HB3 TRP A 25 -3.806 7.919 4.934 1.00 74.54 H +ATOM 418 HD1 TRP A 25 -2.171 9.331 6.710 1.00 4.43 H +ATOM 419 HE1 TRP A 25 0.188 8.760 7.552 1.00 5.51 H +ATOM 420 HE3 TRP A 25 -2.027 4.350 5.516 1.00 25.34 H +ATOM 421 HZ2 TRP A 25 1.882 6.529 7.680 1.00 13.54 H +ATOM 422 HZ3 TRP A 25 0.012 3.071 6.015 1.00 14.21 H +ATOM 423 HH2 TRP A 25 1.930 4.145 7.078 1.00 11.34 H +ATOM 424 N PRO A 26 -7.259 7.145 6.502 1.00 24.03 N +ATOM 425 CA PRO A 26 -8.593 6.937 5.867 1.00 2.11 C +ATOM 426 C PRO A 26 -8.743 7.702 4.533 1.00 31.42 C +ATOM 427 O PRO A 26 -9.574 7.344 3.688 1.00 72.02 O +ATOM 428 CB PRO A 26 -9.574 7.471 6.940 1.00 12.54 C +ATOM 429 CG PRO A 26 -8.773 8.468 7.726 1.00 41.01 C +ATOM 430 CD PRO A 26 -7.375 7.898 7.786 1.00 32.11 C +ATOM 431 HA PRO A 26 -8.783 5.880 5.689 1.00 13.22 H +ATOM 432 HB2 PRO A 26 -10.443 7.936 6.476 1.00 1.43 H +ATOM 433 HB3 PRO A 26 -9.895 6.661 7.584 1.00 60.14 H +ATOM 434 HG2 PRO A 26 -8.774 9.433 7.216 1.00 3.40 H +ATOM 435 HG3 PRO A 26 -9.178 8.575 8.726 1.00 1.32 H +ATOM 436 HD2 PRO A 26 -6.637 8.693 7.842 1.00 32.13 H +ATOM 437 HD3 PRO A 26 -7.264 7.227 8.632 1.00 33.21 H +ATOM 438 N LYS A 27 -7.938 8.763 4.364 1.00 31.03 N +ATOM 439 CA LYS A 27 -7.950 9.604 3.151 1.00 60.02 C +ATOM 440 C LYS A 27 -7.122 8.980 2.014 1.00 13.44 C +ATOM 441 O LYS A 27 -7.297 9.358 0.848 1.00 44.42 O +ATOM 442 CB LYS A 27 -7.404 11.012 3.479 1.00 73.31 C +ATOM 443 CG LYS A 27 -5.895 11.062 3.831 1.00 25.10 C +ATOM 444 CD LYS A 27 -5.385 12.495 4.116 1.00 53.43 C +ATOM 445 CE LYS A 27 -5.573 13.459 2.929 1.00 1.53 C +ATOM 446 NZ LYS A 27 -5.106 14.835 3.253 1.00 54.22 N +ATOM 447 H LYS A 27 -7.320 8.997 5.090 1.00 53.43 H +ATOM 448 HA LYS A 27 -8.980 9.699 2.818 1.00 14.33 H +ATOM 449 HB2 LYS A 27 -7.577 11.655 2.623 1.00 74.55 H +ATOM 450 HB3 LYS A 27 -7.960 11.410 4.322 1.00 73.32 H +ATOM 451 HG2 LYS A 27 -5.726 10.452 4.710 1.00 72.02 H +ATOM 452 HG3 LYS A 27 -5.329 10.645 3.004 1.00 1.01 H +ATOM 453 HD2 LYS A 27 -5.916 12.894 4.972 1.00 62.43 H +ATOM 454 HD3 LYS A 27 -4.328 12.442 4.353 1.00 32.32 H +ATOM 455 HE2 LYS A 27 -5.009 13.087 2.081 1.00 22.14 H +ATOM 456 HE3 LYS A 27 -6.625 13.497 2.663 1.00 13.52 H +ATOM 457 HZ1 LYS A 27 -4.107 14.820 3.546 1.00 35.14 H +ATOM 458 HZ2 LYS A 27 -5.672 15.234 4.031 1.00 11.43 H +ATOM 459 HZ3 LYS A 27 -5.202 15.457 2.425 1.00 23.01 H +ATOM 460 N ALA A 28 -6.217 8.045 2.367 1.00 12.43 N +ATOM 461 CA ALA A 28 -5.311 7.404 1.406 1.00 72.14 C +ATOM 462 C ALA A 28 -6.116 6.603 0.386 1.00 5.21 C +ATOM 463 O ALA A 28 -6.763 5.605 0.742 1.00 14.23 O +ATOM 464 CB ALA A 28 -4.298 6.504 2.129 1.00 53.02 C +ATOM 465 H ALA A 28 -6.159 7.787 3.307 1.00 4.30 H +ATOM 466 HA ALA A 28 -4.759 8.192 0.896 1.00 41.20 H +ATOM 467 HB1 ALA A 28 -4.820 5.720 2.667 1.00 73.23 H +ATOM 468 HB2 ALA A 28 -3.726 7.093 2.832 1.00 42.20 H +ATOM 469 HB3 ALA A 28 -3.622 6.055 1.413 1.00 34.15 H +ATOM 470 N THR A 29 -6.107 7.081 -0.867 1.00 52.20 N +ATOM 471 CA THR A 29 -6.800 6.436 -1.970 1.00 25.43 C +ATOM 472 C THR A 29 -6.153 5.072 -2.264 1.00 31.42 C +ATOM 473 O THR A 29 -5.064 5.005 -2.833 1.00 24.15 O +ATOM 474 CB THR A 29 -6.751 7.368 -3.231 1.00 2.23 C +ATOM 475 OG1 THR A 29 -7.340 8.644 -2.909 1.00 12.00 O +ATOM 476 CG2 THR A 29 -7.470 6.766 -4.452 1.00 65.23 C +ATOM 477 H THR A 29 -5.620 7.912 -1.064 1.00 32.20 H +ATOM 478 HA THR A 29 -7.840 6.297 -1.688 1.00 35.34 H +ATOM 479 HB THR A 29 -5.711 7.535 -3.492 1.00 32.52 H +ATOM 480 HG1 THR A 29 -7.627 9.078 -3.719 1.00 44.41 H +ATOM 481 HG21 THR A 29 -7.410 7.454 -5.284 1.00 41.10 H +ATOM 482 HG22 THR A 29 -8.511 6.583 -4.211 1.00 1.40 H +ATOM 483 HG23 THR A 29 -7.000 5.831 -4.730 1.00 75.12 H +ATOM 484 N VAL A 30 -6.825 3.999 -1.811 1.00 24.21 N +ATOM 485 CA VAL A 30 -6.409 2.611 -2.050 1.00 60.13 C +ATOM 486 C VAL A 30 -7.393 1.990 -3.050 1.00 1.03 C +ATOM 487 O VAL A 30 -8.528 1.652 -2.694 1.00 63.11 O +ATOM 488 CB VAL A 30 -6.386 1.770 -0.709 1.00 33.01 C +ATOM 489 CG1 VAL A 30 -5.926 0.314 -0.957 1.00 42.52 C +ATOM 490 CG2 VAL A 30 -5.504 2.448 0.362 1.00 41.12 C +ATOM 491 H VAL A 30 -7.646 4.149 -1.299 1.00 25.23 H +ATOM 492 HA VAL A 30 -5.401 2.607 -2.479 1.00 41.20 H +ATOM 493 HB VAL A 30 -7.405 1.730 -0.321 1.00 75.21 H +ATOM 494 HG11 VAL A 30 -5.949 -0.241 -0.027 1.00 10.52 H +ATOM 495 HG12 VAL A 30 -4.917 0.309 -1.348 1.00 13.41 H +ATOM 496 HG13 VAL A 30 -6.585 -0.164 -1.671 1.00 53.41 H +ATOM 497 HG21 VAL A 30 -5.883 3.442 0.568 1.00 52.54 H +ATOM 498 HG22 VAL A 30 -4.483 2.525 0.004 1.00 62.13 H +ATOM 499 HG23 VAL A 30 -5.518 1.868 1.276 1.00 24.03 H +ATOM 500 N THR A 31 -6.958 1.868 -4.302 1.00 55.04 N +ATOM 501 CA THR A 31 -7.751 1.270 -5.367 1.00 60.43 C +ATOM 502 C THR A 31 -7.339 -0.198 -5.516 1.00 24.21 C +ATOM 503 O THR A 31 -6.258 -0.515 -6.039 1.00 13.42 O +ATOM 504 CB THR A 31 -7.571 2.059 -6.699 1.00 62.43 C +ATOM 505 OG1 THR A 31 -7.874 3.448 -6.480 1.00 13.32 O +ATOM 506 CG2 THR A 31 -8.449 1.516 -7.843 1.00 64.42 C +ATOM 507 H THR A 31 -6.064 2.205 -4.497 1.00 54.33 H +ATOM 508 HA THR A 31 -8.810 1.322 -5.088 1.00 3.32 H +ATOM 509 HB THR A 31 -6.535 1.986 -6.998 1.00 14.33 H +ATOM 510 HG1 THR A 31 -7.968 3.613 -5.537 1.00 50.11 H +ATOM 511 HG21 THR A 31 -9.493 1.563 -7.556 1.00 24.42 H +ATOM 512 HG22 THR A 31 -8.182 0.488 -8.057 1.00 62.42 H +ATOM 513 HG23 THR A 31 -8.299 2.114 -8.730 1.00 43.21 H +ATOM 514 N ARG A 32 -8.200 -1.071 -4.993 1.00 2.24 N +ATOM 515 CA ARG A 32 -8.023 -2.521 -5.042 1.00 73.21 C +ATOM 516 C ARG A 32 -8.326 -3.028 -6.455 1.00 25.20 C +ATOM 517 O ARG A 32 -9.450 -2.895 -6.949 1.00 71.31 O +ATOM 518 CB ARG A 32 -8.982 -3.186 -4.028 1.00 72.44 C +ATOM 519 CG ARG A 32 -8.805 -4.712 -3.878 1.00 40.42 C +ATOM 520 CD ARG A 32 -9.927 -5.356 -3.045 1.00 74.25 C +ATOM 521 NE ARG A 32 -9.544 -6.668 -2.514 1.00 13.41 N +ATOM 522 CZ ARG A 32 -9.736 -7.848 -3.112 1.00 24.33 C +ATOM 523 NH1 ARG A 32 -10.317 -7.938 -4.318 1.00 32.01 N +ATOM 524 NH2 ARG A 32 -9.368 -8.942 -2.476 1.00 13.53 N +ATOM 525 H ARG A 32 -8.936 -0.702 -4.458 1.00 20.03 H +ATOM 526 HA ARG A 32 -6.992 -2.755 -4.771 1.00 52.51 H +ATOM 527 HB2 ARG A 32 -8.833 -2.730 -3.050 1.00 30.01 H +ATOM 528 HB3 ARG A 32 -10.004 -2.989 -4.340 1.00 12.32 H +ATOM 529 HG2 ARG A 32 -8.799 -5.166 -4.864 1.00 43.42 H +ATOM 530 HG3 ARG A 32 -7.852 -4.904 -3.396 1.00 51.24 H +ATOM 531 HD2 ARG A 32 -10.165 -4.712 -2.205 1.00 70.14 H +ATOM 532 HD3 ARG A 32 -10.809 -5.467 -3.667 1.00 22.22 H +ATOM 533 HE ARG A 32 -9.104 -6.669 -1.636 1.00 33.23 H +ATOM 534 HH11 ARG A 32 -10.617 -7.109 -4.795 1.00 33.44 H +ATOM 535 HH12 ARG A 32 -10.451 -8.837 -4.751 1.00 43.11 H +ATOM 536 HH21 ARG A 32 -8.950 -8.886 -1.563 1.00 40.25 H +ATOM 537 HH22 ARG A 32 -9.502 -9.837 -2.902 1.00 20.43 H +ATOM 538 N THR A 33 -7.301 -3.575 -7.101 1.00 45.42 N +ATOM 539 CA THR A 33 -7.369 -4.057 -8.473 1.00 12.14 C +ATOM 540 C THR A 33 -6.565 -5.370 -8.531 1.00 3.24 C +ATOM 541 O THR A 33 -5.426 -5.398 -8.088 1.00 12.00 O +ATOM 542 CB THR A 33 -6.843 -2.962 -9.470 1.00 62.12 C +ATOM 543 OG1 THR A 33 -6.763 -3.476 -10.805 1.00 0.00 O +ATOM 544 CG2 THR A 33 -5.480 -2.373 -9.049 1.00 14.02 C +ATOM 545 H THR A 33 -6.480 -3.790 -6.606 1.00 62.42 H +ATOM 546 HA THR A 33 -8.412 -4.273 -8.716 1.00 44.12 H +ATOM 547 HB THR A 33 -7.566 -2.151 -9.480 1.00 20.11 H +ATOM 548 HG1 THR A 33 -7.234 -4.318 -10.858 1.00 35.15 H +ATOM 549 HG21 THR A 33 -5.171 -1.613 -9.756 1.00 25.43 H +ATOM 550 HG22 THR A 33 -4.735 -3.158 -9.018 1.00 51.31 H +ATOM 551 HG23 THR A 33 -5.566 -1.926 -8.065 1.00 32.14 H +ATOM 552 N ASN A 34 -7.168 -6.458 -9.020 1.00 21.14 N +ATOM 553 CA ASN A 34 -6.518 -7.789 -9.011 1.00 45.11 C +ATOM 554 C ASN A 34 -5.203 -7.744 -9.834 1.00 3.35 C +ATOM 555 O ASN A 34 -5.230 -7.630 -11.068 1.00 13.31 O +ATOM 556 CB ASN A 34 -7.481 -8.886 -9.533 1.00 25.24 C +ATOM 557 CG ASN A 34 -8.761 -9.042 -8.687 1.00 41.14 C +ATOM 558 OD1 ASN A 34 -9.276 -8.077 -8.115 1.00 70.14 O +ATOM 559 ND2 ASN A 34 -9.295 -10.253 -8.611 1.00 52.05 N +ATOM 560 H ASN A 34 -8.072 -6.364 -9.380 1.00 63.24 H +ATOM 561 HA ASN A 34 -6.268 -8.018 -7.975 1.00 53.43 H +ATOM 562 HB2 ASN A 34 -7.777 -8.640 -10.546 1.00 21.15 H +ATOM 563 HB3 ASN A 34 -6.957 -9.838 -9.544 1.00 43.22 H +ATOM 564 HD21 ASN A 34 -8.860 -10.983 -9.096 1.00 30.24 H +ATOM 565 HD22 ASN A 34 -10.105 -10.368 -8.070 1.00 40.43 H +ATOM 566 N GLY A 35 -4.064 -7.806 -9.111 1.00 31.12 N +ATOM 567 CA GLY A 35 -2.731 -7.606 -9.694 1.00 64.42 C +ATOM 568 C GLY A 35 -1.903 -6.562 -8.945 1.00 43.12 C +ATOM 569 O GLY A 35 -0.705 -6.771 -8.717 1.00 44.05 O +ATOM 570 H GLY A 35 -4.132 -8.042 -8.160 1.00 3.54 H +ATOM 571 HA2 GLY A 35 -2.204 -8.551 -9.667 1.00 51.43 H +ATOM 572 HA3 GLY A 35 -2.820 -7.295 -10.730 1.00 70.13 H +ATOM 573 N ASP A 36 -2.538 -5.423 -8.568 1.00 4.03 N +ATOM 574 CA ASP A 36 -1.851 -4.273 -7.912 1.00 61.40 C +ATOM 575 C ASP A 36 -2.739 -3.599 -6.841 1.00 40.54 C +ATOM 576 O ASP A 36 -3.888 -3.967 -6.625 1.00 2.11 O +ATOM 577 CB ASP A 36 -1.433 -3.194 -8.950 1.00 64.42 C +ATOM 578 CG ASP A 36 -0.441 -3.685 -10.016 1.00 53.23 C +ATOM 579 OD1 ASP A 36 0.734 -3.945 -9.680 1.00 32.51 O +ATOM 580 OD2 ASP A 36 -0.827 -3.789 -11.203 1.00 12.42 O +ATOM 581 H ASP A 36 -3.501 -5.351 -8.731 1.00 44.53 H +ATOM 582 HA ASP A 36 -0.957 -4.652 -7.418 1.00 41.30 H +ATOM 583 HB2 ASP A 36 -2.328 -2.831 -9.448 1.00 15.03 H +ATOM 584 HB3 ASP A 36 -0.976 -2.357 -8.426 1.00 14.25 H +ATOM 585 N ILE A 37 -2.158 -2.609 -6.155 1.00 74.43 N +ATOM 586 CA ILE A 37 -2.864 -1.682 -5.263 1.00 3.12 C +ATOM 587 C ILE A 37 -2.442 -0.269 -5.676 1.00 24.14 C +ATOM 588 O ILE A 37 -1.268 0.093 -5.539 1.00 13.30 O +ATOM 589 CB ILE A 37 -2.524 -1.939 -3.733 1.00 1.51 C +ATOM 590 CG1 ILE A 37 -3.137 -3.288 -3.229 1.00 73.41 C +ATOM 591 CG2 ILE A 37 -2.970 -0.756 -2.829 1.00 2.34 C +ATOM 592 CD1 ILE A 37 -4.658 -3.371 -3.265 1.00 53.02 C +ATOM 593 H ILE A 37 -1.194 -2.481 -6.260 1.00 62.11 H +ATOM 594 HA ILE A 37 -3.939 -1.793 -5.412 1.00 52.32 H +ATOM 595 HB ILE A 37 -1.438 -2.009 -3.652 1.00 41.15 H +ATOM 596 HG12 ILE A 37 -2.762 -4.095 -3.845 1.00 22.20 H +ATOM 597 HG13 ILE A 37 -2.821 -3.463 -2.207 1.00 2.44 H +ATOM 598 HG21 ILE A 37 -2.450 0.147 -3.124 1.00 55.42 H +ATOM 599 HG22 ILE A 37 -2.735 -0.977 -1.797 1.00 72.05 H +ATOM 600 HG23 ILE A 37 -4.039 -0.601 -2.926 1.00 53.44 H +ATOM 601 HD11 ILE A 37 -5.005 -3.253 -4.282 1.00 63.30 H +ATOM 602 HD12 ILE A 37 -5.083 -2.591 -2.646 1.00 24.13 H +ATOM 603 HD13 ILE A 37 -4.972 -4.334 -2.890 1.00 32.44 H +ATOM 604 N LYS A 38 -3.381 0.514 -6.217 1.00 61.04 N +ATOM 605 CA LYS A 38 -3.106 1.893 -6.626 1.00 52.41 C +ATOM 606 C LYS A 38 -3.282 2.812 -5.396 1.00 70.10 C +ATOM 607 O LYS A 38 -4.402 3.096 -4.984 1.00 62.42 O +ATOM 608 CB LYS A 38 -4.037 2.306 -7.820 1.00 44.41 C +ATOM 609 CG LYS A 38 -3.470 2.062 -9.248 1.00 53.32 C +ATOM 610 CD LYS A 38 -3.125 0.586 -9.562 1.00 63.45 C +ATOM 611 CE LYS A 38 -2.641 0.393 -11.016 1.00 75.04 C +ATOM 612 NZ LYS A 38 -2.286 -1.023 -11.308 1.00 4.01 N +ATOM 613 H LYS A 38 -4.286 0.160 -6.327 1.00 32.35 H +ATOM 614 HA LYS A 38 -2.066 1.949 -6.957 1.00 25.20 H +ATOM 615 HB2 LYS A 38 -4.966 1.757 -7.743 1.00 24.14 H +ATOM 616 HB3 LYS A 38 -4.270 3.366 -7.738 1.00 72.02 H +ATOM 617 HG2 LYS A 38 -4.202 2.403 -9.972 1.00 62.22 H +ATOM 618 HG3 LYS A 38 -2.570 2.661 -9.359 1.00 0.13 H +ATOM 619 HD2 LYS A 38 -2.341 0.255 -8.888 1.00 33.42 H +ATOM 620 HD3 LYS A 38 -4.008 -0.025 -9.403 1.00 60.02 H +ATOM 621 HE2 LYS A 38 -3.425 0.702 -11.699 1.00 10.42 H +ATOM 622 HE3 LYS A 38 -1.764 1.012 -11.182 1.00 44.12 H +ATOM 623 HZ1 LYS A 38 -1.472 -1.318 -10.729 1.00 24.14 H +ATOM 624 HZ2 LYS A 38 -2.032 -1.127 -12.309 1.00 41.45 H +ATOM 625 HZ3 LYS A 38 -3.090 -1.647 -11.102 1.00 43.13 H +ATOM 626 N LEU A 39 -2.148 3.264 -4.824 1.00 43.21 N +ATOM 627 CA LEU A 39 -2.105 4.091 -3.599 1.00 50.23 C +ATOM 628 C LEU A 39 -1.423 5.431 -3.905 1.00 2.13 C +ATOM 629 O LEU A 39 -0.548 5.518 -4.778 1.00 24.15 O +ATOM 630 CB LEU A 39 -1.340 3.340 -2.460 1.00 13.42 C +ATOM 631 CG LEU A 39 -1.143 4.110 -1.105 1.00 41.31 C +ATOM 632 CD1 LEU A 39 -2.493 4.485 -0.467 1.00 52.51 C +ATOM 633 CD2 LEU A 39 -0.264 3.304 -0.120 1.00 61.43 C +ATOM 634 H LEU A 39 -1.296 3.034 -5.245 1.00 41.13 H +ATOM 635 HA LEU A 39 -3.125 4.281 -3.270 1.00 1.43 H +ATOM 636 HB2 LEU A 39 -1.871 2.416 -2.250 1.00 72.54 H +ATOM 637 HB3 LEU A 39 -0.356 3.074 -2.841 1.00 53.22 H +ATOM 638 HG LEU A 39 -0.625 5.041 -1.310 1.00 22.52 H +ATOM 639 HD11 LEU A 39 -3.065 3.590 -0.257 1.00 11.34 H +ATOM 640 HD12 LEU A 39 -3.055 5.116 -1.146 1.00 62.30 H +ATOM 641 HD13 LEU A 39 -2.324 5.026 0.454 1.00 31.42 H +ATOM 642 HD21 LEU A 39 0.709 3.133 -0.557 1.00 52.22 H +ATOM 643 HD22 LEU A 39 -0.733 2.352 0.102 1.00 53.13 H +ATOM 644 HD23 LEU A 39 -0.143 3.863 0.801 1.00 2.45 H +ATOM 645 N ASP A 40 -1.849 6.483 -3.198 1.00 15.05 N +ATOM 646 CA ASP A 40 -1.257 7.825 -3.294 1.00 34.23 C +ATOM 647 C ASP A 40 -0.899 8.328 -1.886 1.00 42.02 C +ATOM 648 O ASP A 40 -1.756 8.368 -0.994 1.00 2.21 O +ATOM 649 CB ASP A 40 -2.243 8.798 -4.001 1.00 5.13 C +ATOM 650 CG ASP A 40 -2.450 8.479 -5.499 1.00 73.31 C +ATOM 651 OD1 ASP A 40 -3.190 7.525 -5.826 1.00 50.44 O +ATOM 652 OD2 ASP A 40 -1.873 9.181 -6.359 1.00 24.42 O +ATOM 653 H ASP A 40 -2.600 6.350 -2.578 1.00 2.01 H +ATOM 654 HA ASP A 40 -0.341 7.757 -3.883 1.00 32.43 H +ATOM 655 HB2 ASP A 40 -3.207 8.743 -3.506 1.00 63.12 H +ATOM 656 HB3 ASP A 40 -1.870 9.813 -3.911 1.00 15.54 H +ATOM 657 N ALA A 41 0.388 8.655 -1.684 1.00 12.10 N +ATOM 658 CA ALA A 41 0.881 9.322 -0.470 1.00 60.52 C +ATOM 659 C ALA A 41 0.787 10.842 -0.617 1.00 55.04 C +ATOM 660 O ALA A 41 0.584 11.357 -1.723 1.00 74.01 O +ATOM 661 CB ALA A 41 2.325 8.893 -0.177 1.00 1.50 C +ATOM 662 H ALA A 41 1.032 8.429 -2.381 1.00 12.11 H +ATOM 663 HA ALA A 41 0.260 9.017 0.370 1.00 21.43 H +ATOM 664 HB1 ALA A 41 2.970 9.186 -0.994 1.00 62.43 H +ATOM 665 HB2 ALA A 41 2.367 7.817 -0.059 1.00 71.44 H +ATOM 666 HB3 ALA A 41 2.673 9.361 0.737 1.00 23.11 H +ATOM 667 N GLN A 42 0.925 11.552 0.511 1.00 15.15 N +ATOM 668 CA GLN A 42 0.849 13.022 0.554 1.00 63.40 C +ATOM 669 C GLN A 42 2.250 13.650 0.355 1.00 30.54 C +ATOM 670 O GLN A 42 2.436 14.547 -0.471 1.00 0.13 O +ATOM 671 CB GLN A 42 0.229 13.481 1.903 1.00 41.42 C +ATOM 672 CG GLN A 42 -1.119 12.811 2.270 1.00 61.21 C +ATOM 673 CD GLN A 42 -2.255 13.038 1.255 1.00 61.10 C +ATOM 674 OE1 GLN A 42 -3.102 12.165 1.059 1.00 4.23 O +ATOM 675 NE2 GLN A 42 -2.324 14.218 0.644 1.00 34.44 N +ATOM 676 H GLN A 42 1.077 11.067 1.348 1.00 51.22 H +ATOM 677 HA GLN A 42 0.201 13.352 -0.260 1.00 1.10 H +ATOM 678 HB2 GLN A 42 0.932 13.273 2.704 1.00 35.43 H +ATOM 679 HB3 GLN A 42 0.068 14.553 1.862 1.00 61.21 H +ATOM 680 HG2 GLN A 42 -0.958 11.744 2.366 1.00 4.25 H +ATOM 681 HG3 GLN A 42 -1.445 13.198 3.230 1.00 1.22 H +ATOM 682 HE21 GLN A 42 -1.655 14.900 0.860 1.00 13.33 H +ATOM 683 HE22 GLN A 42 -3.045 14.357 -0.008 1.00 63.11 H +ATOM 684 N THR A 43 3.225 13.158 1.141 1.00 13.45 N +ATOM 685 CA THR A 43 4.625 13.647 1.149 1.00 53.41 C +ATOM 686 C THR A 43 5.585 12.443 1.052 1.00 4.12 C +ATOM 687 O THR A 43 5.123 11.293 1.039 1.00 5.04 O +ATOM 688 CB THR A 43 4.930 14.465 2.458 1.00 40.03 C +ATOM 689 OG1 THR A 43 4.841 13.601 3.607 1.00 52.55 O +ATOM 690 CG2 THR A 43 3.968 15.662 2.641 1.00 33.43 C +ATOM 691 H THR A 43 3.003 12.421 1.739 1.00 3.14 H +ATOM 692 HA THR A 43 4.783 14.293 0.288 1.00 32.15 H +ATOM 693 HB THR A 43 5.944 14.848 2.400 1.00 4.31 H +ATOM 694 HG1 THR A 43 4.342 14.039 4.304 1.00 24.14 H +ATOM 695 HG21 THR A 43 4.224 16.202 3.543 1.00 2.21 H +ATOM 696 HG22 THR A 43 2.948 15.304 2.719 1.00 14.15 H +ATOM 697 HG23 THR A 43 4.045 16.332 1.793 1.00 32.41 H +ATOM 698 N GLU A 44 6.910 12.711 0.978 1.00 50.32 N +ATOM 699 CA GLU A 44 7.946 11.650 0.911 1.00 53.43 C +ATOM 700 C GLU A 44 7.924 10.811 2.187 1.00 64.41 C +ATOM 701 O GLU A 44 7.879 9.590 2.118 1.00 41.32 O +ATOM 702 CB GLU A 44 9.386 12.210 0.689 1.00 23.13 C +ATOM 703 CG GLU A 44 9.619 12.935 -0.651 1.00 45.33 C +ATOM 704 CD GLU A 44 8.923 14.300 -0.730 1.00 42.32 C +ATOM 705 OE1 GLU A 44 9.439 15.272 -0.148 1.00 72.12 O +ATOM 706 OE2 GLU A 44 7.845 14.405 -1.348 1.00 73.25 O +ATOM 707 H GLU A 44 7.198 13.648 0.959 1.00 23.32 H +ATOM 708 HA GLU A 44 7.691 11.009 0.069 1.00 13.10 H +ATOM 709 HB2 GLU A 44 9.625 12.902 1.495 1.00 71.53 H +ATOM 710 HB3 GLU A 44 10.089 11.379 0.745 1.00 22.15 H +ATOM 711 HG2 GLU A 44 10.688 13.081 -0.790 1.00 2.13 H +ATOM 712 HG3 GLU A 44 9.252 12.299 -1.452 1.00 60.04 H +ATOM 713 N LYS A 45 7.930 11.506 3.346 1.00 41.32 N +ATOM 714 CA LYS A 45 7.881 10.878 4.682 1.00 71.12 C +ATOM 715 C LYS A 45 6.612 10.033 4.829 1.00 21.24 C +ATOM 716 O LYS A 45 6.661 8.929 5.377 1.00 54.31 O +ATOM 717 CB LYS A 45 7.909 11.951 5.801 1.00 73.31 C +ATOM 718 CG LYS A 45 7.915 11.385 7.246 1.00 2.23 C +ATOM 719 CD LYS A 45 7.646 12.475 8.311 1.00 3.10 C +ATOM 720 CE LYS A 45 6.233 13.067 8.195 1.00 22.11 C +ATOM 721 NZ LYS A 45 6.000 14.156 9.179 1.00 1.33 N +ATOM 722 H LYS A 45 7.961 12.484 3.295 1.00 65.25 H +ATOM 723 HA LYS A 45 8.754 10.240 4.780 1.00 14.32 H +ATOM 724 HB2 LYS A 45 8.800 12.559 5.673 1.00 31.35 H +ATOM 725 HB3 LYS A 45 7.041 12.593 5.685 1.00 24.21 H +ATOM 726 HG2 LYS A 45 7.147 10.618 7.331 1.00 43.22 H +ATOM 727 HG3 LYS A 45 8.882 10.932 7.442 1.00 22.52 H +ATOM 728 HD2 LYS A 45 7.761 12.040 9.297 1.00 24.31 H +ATOM 729 HD3 LYS A 45 8.372 13.275 8.193 1.00 1.34 H +ATOM 730 HE2 LYS A 45 6.096 13.467 7.198 1.00 32.24 H +ATOM 731 HE3 LYS A 45 5.502 12.282 8.364 1.00 63.14 H +ATOM 732 HZ1 LYS A 45 6.028 13.777 10.146 1.00 61.01 H +ATOM 733 HZ2 LYS A 45 5.074 14.597 9.020 1.00 4.12 H +ATOM 734 HZ3 LYS A 45 6.736 14.884 9.089 1.00 71.30 H +ATOM 735 N GLU A 46 5.491 10.569 4.308 1.00 33.42 N +ATOM 736 CA GLU A 46 4.193 9.886 4.333 1.00 72.32 C +ATOM 737 C GLU A 46 4.291 8.555 3.564 1.00 51.20 C +ATOM 738 O GLU A 46 3.831 7.522 4.040 1.00 31.23 O +ATOM 739 CB GLU A 46 3.087 10.781 3.711 1.00 75.21 C +ATOM 740 CG GLU A 46 1.646 10.364 4.068 1.00 15.30 C +ATOM 741 CD GLU A 46 1.267 10.675 5.533 1.00 44.21 C +ATOM 742 OE1 GLU A 46 1.661 9.914 6.448 1.00 52.41 O +ATOM 743 OE2 GLU A 46 0.595 11.703 5.780 1.00 13.12 O +ATOM 744 H GLU A 46 5.547 11.459 3.894 1.00 14.01 H +ATOM 745 HA GLU A 46 3.949 9.683 5.368 1.00 32.02 H +ATOM 746 HB2 GLU A 46 3.238 11.802 4.043 1.00 65.33 H +ATOM 747 HB3 GLU A 46 3.189 10.766 2.625 1.00 41.21 H +ATOM 748 HG2 GLU A 46 0.960 10.884 3.404 1.00 5.41 H +ATOM 749 HG3 GLU A 46 1.541 9.296 3.899 1.00 33.14 H +ATOM 750 N ALA A 47 4.910 8.618 2.369 1.00 4.52 N +ATOM 751 CA ALA A 47 5.235 7.441 1.546 1.00 1.03 C +ATOM 752 C ALA A 47 6.148 6.438 2.262 1.00 3.24 C +ATOM 753 O ALA A 47 5.959 5.235 2.107 1.00 44.34 O +ATOM 754 CB ALA A 47 5.882 7.886 0.231 1.00 25.11 C +ATOM 755 H ALA A 47 5.100 9.497 1.984 1.00 73.32 H +ATOM 756 HA ALA A 47 4.298 6.950 1.300 1.00 45.41 H +ATOM 757 HB1 ALA A 47 5.230 8.588 -0.272 1.00 22.12 H +ATOM 758 HB2 ALA A 47 6.040 7.028 -0.411 1.00 60.31 H +ATOM 759 HB3 ALA A 47 6.834 8.365 0.428 1.00 71.11 H +ATOM 760 N GLU A 48 7.133 6.943 3.040 1.00 5.34 N +ATOM 761 CA GLU A 48 8.068 6.090 3.805 1.00 35.32 C +ATOM 762 C GLU A 48 7.306 5.206 4.811 1.00 63.21 C +ATOM 763 O GLU A 48 7.683 4.068 5.053 1.00 13.45 O +ATOM 764 CB GLU A 48 9.123 6.931 4.582 1.00 23.33 C +ATOM 765 CG GLU A 48 9.977 7.897 3.734 1.00 54.02 C +ATOM 766 CD GLU A 48 10.844 7.232 2.648 1.00 60.41 C +ATOM 767 OE1 GLU A 48 11.463 6.181 2.920 1.00 24.54 O +ATOM 768 OE2 GLU A 48 10.940 7.778 1.527 1.00 54.41 O +ATOM 769 H GLU A 48 7.230 7.915 3.102 1.00 12.31 H +ATOM 770 HA GLU A 48 8.583 5.452 3.091 1.00 71.52 H +ATOM 771 HB2 GLU A 48 8.608 7.522 5.335 1.00 71.11 H +ATOM 772 HB3 GLU A 48 9.797 6.250 5.093 1.00 2.12 H +ATOM 773 HG2 GLU A 48 9.309 8.604 3.264 1.00 71.13 H +ATOM 774 HG3 GLU A 48 10.633 8.448 4.404 1.00 13.32 H +ATOM 775 N LYS A 49 6.235 5.778 5.380 1.00 64.25 N +ATOM 776 CA LYS A 49 5.367 5.117 6.369 1.00 70.22 C +ATOM 777 C LYS A 49 4.402 4.132 5.671 1.00 74.34 C +ATOM 778 O LYS A 49 4.205 3.007 6.128 1.00 52.33 O +ATOM 779 CB LYS A 49 4.554 6.205 7.110 1.00 72.41 C +ATOM 780 CG LYS A 49 5.402 7.304 7.785 1.00 52.25 C +ATOM 781 CD LYS A 49 4.562 8.545 8.153 1.00 42.12 C +ATOM 782 CE LYS A 49 3.463 8.242 9.176 1.00 0.11 C +ATOM 783 NZ LYS A 49 2.527 9.379 9.341 1.00 43.14 N +ATOM 784 H LYS A 49 6.011 6.695 5.110 1.00 14.41 H +ATOM 785 HA LYS A 49 5.992 4.585 7.084 1.00 61.44 H +ATOM 786 HB2 LYS A 49 3.886 6.685 6.393 1.00 41.53 H +ATOM 787 HB3 LYS A 49 3.944 5.729 7.872 1.00 5.01 H +ATOM 788 HG2 LYS A 49 5.854 6.898 8.686 1.00 73.22 H +ATOM 789 HG3 LYS A 49 6.191 7.605 7.103 1.00 4.32 H +ATOM 790 HD2 LYS A 49 5.216 9.303 8.563 1.00 51.33 H +ATOM 791 HD3 LYS A 49 4.100 8.934 7.249 1.00 43.41 H +ATOM 792 HE2 LYS A 49 2.902 7.377 8.857 1.00 70.43 H +ATOM 793 HE3 LYS A 49 3.922 8.030 10.135 1.00 13.23 H +ATOM 794 HZ1 LYS A 49 1.752 9.112 9.978 1.00 54.11 H +ATOM 795 HZ2 LYS A 49 2.122 9.650 8.417 1.00 54.31 H +ATOM 796 HZ3 LYS A 49 3.023 10.198 9.739 1.00 62.31 H +ATOM 797 N MET A 50 3.775 4.633 4.589 1.00 42.01 N +ATOM 798 CA MET A 50 2.802 3.873 3.772 1.00 11.52 C +ATOM 799 C MET A 50 3.420 2.573 3.214 1.00 42.40 C +ATOM 800 O MET A 50 2.943 1.478 3.535 1.00 51.44 O +ATOM 801 CB MET A 50 2.197 4.747 2.633 1.00 63.23 C +ATOM 802 CG MET A 50 1.212 5.822 3.112 1.00 21.15 C +ATOM 803 SD MET A 50 0.400 6.675 1.747 1.00 21.10 S +ATOM 804 CE MET A 50 -0.745 7.743 2.622 1.00 54.34 C +ATOM 805 H MET A 50 3.960 5.570 4.404 1.00 52.32 H +ATOM 806 HA MET A 50 1.989 3.589 4.441 1.00 51.22 H +ATOM 807 HB2 MET A 50 3.001 5.243 2.100 1.00 14.13 H +ATOM 808 HB3 MET A 50 1.669 4.105 1.933 1.00 62.21 H +ATOM 809 HG2 MET A 50 0.450 5.354 3.727 1.00 70.10 H +ATOM 810 HG3 MET A 50 1.749 6.551 3.705 1.00 63.14 H +ATOM 811 HE1 MET A 50 -0.197 8.411 3.270 1.00 70.42 H +ATOM 812 HE2 MET A 50 -1.421 7.141 3.212 1.00 62.43 H +ATOM 813 HE3 MET A 50 -1.310 8.320 1.906 1.00 11.20 H +ATOM 814 N GLU A 51 4.492 2.701 2.405 1.00 21.42 N +ATOM 815 CA GLU A 51 5.214 1.536 1.832 1.00 34.03 C +ATOM 816 C GLU A 51 5.744 0.579 2.940 1.00 32.31 C +ATOM 817 O GLU A 51 5.833 -0.624 2.731 1.00 53.44 O +ATOM 818 CB GLU A 51 6.378 2.003 0.905 1.00 60.04 C +ATOM 819 CG GLU A 51 7.605 2.576 1.630 1.00 12.31 C +ATOM 820 CD GLU A 51 8.730 3.003 0.675 1.00 63.50 C +ATOM 821 OE1 GLU A 51 9.509 2.126 0.229 1.00 33.11 O +ATOM 822 OE2 GLU A 51 8.848 4.212 0.368 1.00 3.55 O +ATOM 823 H GLU A 51 4.773 3.600 2.140 1.00 1.21 H +ATOM 824 HA GLU A 51 4.495 0.987 1.222 1.00 13.30 H +ATOM 825 HB2 GLU A 51 6.706 1.158 0.309 1.00 54.41 H +ATOM 826 HB3 GLU A 51 5.997 2.766 0.231 1.00 32.21 H +ATOM 827 HG2 GLU A 51 7.282 3.429 2.208 1.00 22.21 H +ATOM 828 HG3 GLU A 51 7.991 1.824 2.315 1.00 44.42 H +ATOM 829 N LYS A 52 6.030 1.154 4.130 1.00 33.23 N +ATOM 830 CA LYS A 52 6.533 0.404 5.305 1.00 13.13 C +ATOM 831 C LYS A 52 5.394 -0.429 5.923 1.00 72.15 C +ATOM 832 O LYS A 52 5.613 -1.567 6.334 1.00 32.24 O +ATOM 833 CB LYS A 52 7.142 1.364 6.362 1.00 72.32 C +ATOM 834 CG LYS A 52 7.771 0.678 7.598 1.00 53.30 C +ATOM 835 CD LYS A 52 8.338 1.687 8.632 1.00 41.24 C +ATOM 836 CE LYS A 52 7.254 2.610 9.228 1.00 72.21 C +ATOM 837 NZ LYS A 52 7.820 3.567 10.225 1.00 71.21 N +ATOM 838 H LYS A 52 5.836 2.112 4.192 1.00 73.30 H +ATOM 839 HA LYS A 52 7.311 -0.273 4.957 1.00 74.44 H +ATOM 840 HB2 LYS A 52 7.914 1.956 5.882 1.00 62.43 H +ATOM 841 HB3 LYS A 52 6.364 2.040 6.707 1.00 2.33 H +ATOM 842 HG2 LYS A 52 7.018 0.063 8.082 1.00 54.11 H +ATOM 843 HG3 LYS A 52 8.579 0.034 7.258 1.00 43.30 H +ATOM 844 HD2 LYS A 52 8.804 1.138 9.439 1.00 1.21 H +ATOM 845 HD3 LYS A 52 9.091 2.304 8.147 1.00 70.04 H +ATOM 846 HE2 LYS A 52 6.792 3.179 8.430 1.00 0.41 H +ATOM 847 HE3 LYS A 52 6.500 2.004 9.716 1.00 12.22 H +ATOM 848 HZ1 LYS A 52 8.273 3.047 11.007 1.00 34.14 H +ATOM 849 HZ2 LYS A 52 7.068 4.163 10.616 1.00 12.35 H +ATOM 850 HZ3 LYS A 52 8.530 4.176 9.774 1.00 24.24 H +ATOM 851 N ALA A 53 4.175 0.149 5.948 1.00 1.43 N +ATOM 852 CA ALA A 53 2.961 -0.514 6.473 1.00 64.32 C +ATOM 853 C ALA A 53 2.580 -1.724 5.600 1.00 24.25 C +ATOM 854 O ALA A 53 2.102 -2.748 6.106 1.00 3.44 O +ATOM 855 CB ALA A 53 1.795 0.487 6.557 1.00 72.12 C +ATOM 856 H ALA A 53 4.088 1.060 5.600 1.00 53.42 H +ATOM 857 HA ALA A 53 3.181 -0.862 7.478 1.00 63.03 H +ATOM 858 HB1 ALA A 53 2.084 1.325 7.179 1.00 51.22 H +ATOM 859 HB2 ALA A 53 0.925 0.006 6.987 1.00 23.13 H +ATOM 860 HB3 ALA A 53 1.550 0.850 5.566 1.00 70.21 H +ATOM 861 N VAL A 54 2.799 -1.575 4.286 1.00 21.33 N +ATOM 862 CA VAL A 54 2.700 -2.675 3.313 1.00 73.14 C +ATOM 863 C VAL A 54 3.737 -3.784 3.628 1.00 5.15 C +ATOM 864 O VAL A 54 3.426 -4.976 3.581 1.00 21.44 O +ATOM 865 CB VAL A 54 2.942 -2.132 1.859 1.00 34.11 C +ATOM 866 CG1 VAL A 54 2.881 -3.260 0.812 1.00 31.20 C +ATOM 867 CG2 VAL A 54 1.952 -0.996 1.519 1.00 32.32 C +ATOM 868 H VAL A 54 3.013 -0.680 3.946 1.00 14.30 H +ATOM 869 HA VAL A 54 1.696 -3.090 3.370 1.00 43.44 H +ATOM 870 HB VAL A 54 3.946 -1.710 1.826 1.00 70.14 H +ATOM 871 HG11 VAL A 54 1.896 -3.709 0.809 1.00 22.40 H +ATOM 872 HG12 VAL A 54 3.618 -4.020 1.045 1.00 35.10 H +ATOM 873 HG13 VAL A 54 3.092 -2.856 -0.170 1.00 74.31 H +ATOM 874 HG21 VAL A 54 0.937 -1.370 1.560 1.00 53.02 H +ATOM 875 HG22 VAL A 54 2.154 -0.615 0.526 1.00 2.33 H +ATOM 876 HG23 VAL A 54 2.062 -0.191 2.236 1.00 42.11 H +ATOM 877 N LYS A 55 4.979 -3.356 3.921 1.00 0.22 N +ATOM 878 CA LYS A 55 6.091 -4.261 4.295 1.00 2.30 C +ATOM 879 C LYS A 55 5.876 -4.948 5.662 1.00 73.04 C +ATOM 880 O LYS A 55 6.559 -5.929 5.972 1.00 33.04 O +ATOM 881 CB LYS A 55 7.440 -3.497 4.237 1.00 75.32 C +ATOM 882 CG LYS A 55 7.804 -3.002 2.815 1.00 32.41 C +ATOM 883 CD LYS A 55 8.984 -2.006 2.801 1.00 42.13 C +ATOM 884 CE LYS A 55 9.219 -1.371 1.422 1.00 10.41 C +ATOM 885 NZ LYS A 55 9.526 -2.376 0.370 1.00 22.32 N +ATOM 886 H LYS A 55 5.162 -2.398 3.824 1.00 60.33 H +ATOM 887 HA LYS A 55 6.116 -5.043 3.545 1.00 73.12 H +ATOM 888 HB2 LYS A 55 7.386 -2.637 4.902 1.00 74.13 H +ATOM 889 HB3 LYS A 55 8.240 -4.150 4.583 1.00 14.33 H +ATOM 890 HG2 LYS A 55 8.060 -3.859 2.201 1.00 64.15 H +ATOM 891 HG3 LYS A 55 6.930 -2.515 2.386 1.00 11.21 H +ATOM 892 HD2 LYS A 55 8.780 -1.213 3.514 1.00 45.32 H +ATOM 893 HD3 LYS A 55 9.887 -2.527 3.106 1.00 41.20 H +ATOM 894 HE2 LYS A 55 8.331 -0.824 1.125 1.00 0.11 H +ATOM 895 HE3 LYS A 55 10.049 -0.679 1.491 1.00 33.34 H +ATOM 896 HZ1 LYS A 55 8.725 -3.023 0.243 1.00 24.41 H +ATOM 897 HZ2 LYS A 55 10.367 -2.928 0.639 1.00 73.44 H +ATOM 898 HZ3 LYS A 55 9.719 -1.900 -0.535 1.00 41.42 H +ATOM 899 N LYS A 56 4.914 -4.451 6.467 1.00 4.43 N +ATOM 900 CA LYS A 56 4.488 -5.131 7.718 1.00 44.25 C +ATOM 901 C LYS A 56 3.564 -6.335 7.407 1.00 20.15 C +ATOM 902 O LYS A 56 3.270 -7.146 8.286 1.00 70.42 O +ATOM 903 CB LYS A 56 3.792 -4.131 8.694 1.00 14.40 C +ATOM 904 CG LYS A 56 4.632 -2.879 9.056 1.00 12.44 C +ATOM 905 CD LYS A 56 6.056 -3.199 9.581 1.00 51.51 C +ATOM 906 CE LYS A 56 6.051 -4.005 10.887 1.00 24.51 C +ATOM 907 NZ LYS A 56 7.427 -4.281 11.378 1.00 11.43 N +ATOM 908 H LYS A 56 4.486 -3.601 6.220 1.00 41.43 H +ATOM 909 HA LYS A 56 5.383 -5.517 8.203 1.00 20.41 H +ATOM 910 HB2 LYS A 56 2.866 -3.792 8.242 1.00 24.11 H +ATOM 911 HB3 LYS A 56 3.552 -4.653 9.617 1.00 43.22 H +ATOM 912 HG2 LYS A 56 4.727 -2.268 8.167 1.00 43.13 H +ATOM 913 HG3 LYS A 56 4.100 -2.309 9.811 1.00 73.44 H +ATOM 914 HD2 LYS A 56 6.591 -3.763 8.826 1.00 14.14 H +ATOM 915 HD3 LYS A 56 6.578 -2.262 9.750 1.00 12.01 H +ATOM 916 HE2 LYS A 56 5.518 -3.448 11.648 1.00 10.01 H +ATOM 917 HE3 LYS A 56 5.547 -4.949 10.720 1.00 62.44 H +ATOM 918 HZ1 LYS A 56 7.392 -4.763 12.300 1.00 74.45 H +ATOM 919 HZ2 LYS A 56 7.957 -3.393 11.488 1.00 52.50 H +ATOM 920 HZ3 LYS A 56 7.935 -4.887 10.704 1.00 14.04 H +ATOM 921 N VAL A 57 3.092 -6.413 6.151 1.00 22.14 N +ATOM 922 CA VAL A 57 2.368 -7.580 5.608 1.00 10.13 C +ATOM 923 C VAL A 57 3.358 -8.492 4.844 1.00 25.24 C +ATOM 924 O VAL A 57 3.261 -9.722 4.893 1.00 61.11 O +ATOM 925 CB VAL A 57 1.218 -7.124 4.627 1.00 12.41 C +ATOM 926 CG1 VAL A 57 0.401 -8.329 4.104 1.00 1.03 C +ATOM 927 CG2 VAL A 57 0.306 -6.053 5.279 1.00 5.41 C +ATOM 928 H VAL A 57 3.227 -5.646 5.565 1.00 12.40 H +ATOM 929 HA VAL A 57 1.924 -8.136 6.432 1.00 61.42 H +ATOM 930 HB VAL A 57 1.688 -6.656 3.757 1.00 10.31 H +ATOM 931 HG11 VAL A 57 -0.066 -8.847 4.934 1.00 63.23 H +ATOM 932 HG12 VAL A 57 1.055 -9.016 3.580 1.00 35.33 H +ATOM 933 HG13 VAL A 57 -0.364 -7.983 3.423 1.00 33.04 H +ATOM 934 HG21 VAL A 57 -0.451 -5.740 4.572 1.00 14.21 H +ATOM 935 HG22 VAL A 57 0.901 -5.194 5.567 1.00 12.42 H +ATOM 936 HG23 VAL A 57 -0.176 -6.463 6.159 1.00 4.20 H +ATOM 937 N LYS A 58 4.332 -7.855 4.169 1.00 25.30 N +ATOM 938 CA LYS A 58 5.241 -8.532 3.219 1.00 52.21 C +ATOM 939 C LYS A 58 6.568 -7.726 3.080 1.00 13.41 C +ATOM 940 O LYS A 58 6.593 -6.726 2.361 1.00 41.23 O +ATOM 941 CB LYS A 58 4.531 -8.775 1.848 1.00 53.23 C +ATOM 942 CG LYS A 58 3.796 -7.569 1.242 1.00 53.12 C +ATOM 943 CD LYS A 58 3.174 -7.912 -0.124 1.00 11.12 C +ATOM 944 CE LYS A 58 2.529 -6.708 -0.793 1.00 32.11 C +ATOM 945 NZ LYS A 58 1.812 -7.095 -2.023 1.00 1.32 N +ATOM 946 H LYS A 58 4.557 -6.949 4.457 1.00 14.52 H +ATOM 947 HA LYS A 58 5.483 -9.502 3.648 1.00 23.41 H +ATOM 948 HB2 LYS A 58 5.275 -9.091 1.125 1.00 53.33 H +ATOM 949 HB3 LYS A 58 3.816 -9.582 1.972 1.00 71.24 H +ATOM 950 HG2 LYS A 58 3.007 -7.257 1.923 1.00 20.00 H +ATOM 951 HG3 LYS A 58 4.501 -6.753 1.119 1.00 1.32 H +ATOM 952 HD2 LYS A 58 3.948 -8.294 -0.785 1.00 30.35 H +ATOM 953 HD3 LYS A 58 2.419 -8.681 0.013 1.00 42.44 H +ATOM 954 HE2 LYS A 58 1.824 -6.251 -0.111 1.00 24.33 H +ATOM 955 HE3 LYS A 58 3.295 -5.986 -1.046 1.00 73.13 H +ATOM 956 HZ1 LYS A 58 1.166 -7.881 -1.828 1.00 5.21 H +ATOM 957 HZ2 LYS A 58 2.490 -7.404 -2.748 1.00 40.11 H +ATOM 958 HZ3 LYS A 58 1.266 -6.294 -2.394 1.00 21.11 H +ATOM 959 N PRO A 59 7.692 -8.149 3.761 1.00 23.25 N +ATOM 960 CA PRO A 59 8.977 -7.367 3.807 1.00 64.23 C +ATOM 961 C PRO A 59 9.556 -7.027 2.410 1.00 14.30 C +ATOM 962 O PRO A 59 10.045 -5.911 2.176 1.00 45.55 O +ATOM 963 CB PRO A 59 9.937 -8.298 4.600 1.00 52.51 C +ATOM 964 CG PRO A 59 9.030 -9.182 5.404 1.00 61.14 C +ATOM 965 CD PRO A 59 7.815 -9.415 4.531 1.00 40.22 C +ATOM 966 HA PRO A 59 8.836 -6.440 4.360 1.00 63.41 H +ATOM 967 HB2 PRO A 59 10.553 -8.890 3.919 1.00 34.21 H +ATOM 968 HB3 PRO A 59 10.574 -7.718 5.258 1.00 1.53 H +ATOM 969 HG2 PRO A 59 9.528 -10.123 5.629 1.00 34.23 H +ATOM 970 HG3 PRO A 59 8.735 -8.689 6.326 1.00 51.34 H +ATOM 971 HD2 PRO A 59 7.975 -10.256 3.859 1.00 41.21 H +ATOM 972 HD3 PRO A 59 6.936 -9.587 5.140 1.00 63.34 H +ATOM 973 N ASN A 60 9.438 -7.987 1.485 1.00 32.20 N +ATOM 974 CA ASN A 60 10.027 -7.900 0.130 1.00 45.12 C +ATOM 975 C ASN A 60 8.953 -7.396 -0.879 1.00 3.21 C +ATOM 976 O ASN A 60 8.946 -7.768 -2.055 1.00 72.14 O +ATOM 977 CB ASN A 60 10.601 -9.313 -0.221 1.00 44.11 C +ATOM 978 CG ASN A 60 11.471 -9.373 -1.483 1.00 14.35 C +ATOM 979 OD1 ASN A 60 10.987 -9.656 -2.576 1.00 43.45 O +ATOM 980 ND2 ASN A 60 12.763 -9.124 -1.337 1.00 61.44 N +ATOM 981 H ASN A 60 8.906 -8.785 1.699 1.00 34.24 H +ATOM 982 HA ASN A 60 10.844 -7.182 0.152 1.00 54.41 H +ATOM 983 HB2 ASN A 60 11.205 -9.652 0.611 1.00 31.33 H +ATOM 984 HB3 ASN A 60 9.775 -10.008 -0.341 1.00 13.21 H +ATOM 985 HD21 ASN A 60 13.099 -8.916 -0.436 1.00 55.24 H +ATOM 986 HD22 ASN A 60 13.337 -9.169 -2.133 1.00 53.43 H +ATOM 987 N ALA A 61 8.012 -6.563 -0.381 1.00 72.40 N +ATOM 988 CA ALA A 61 7.013 -5.855 -1.205 1.00 12.15 C +ATOM 989 C ALA A 61 7.660 -5.000 -2.317 1.00 2.12 C +ATOM 990 O ALA A 61 8.379 -4.028 -2.028 1.00 50.05 O +ATOM 991 CB ALA A 61 6.142 -4.963 -0.304 1.00 65.35 C +ATOM 992 H ALA A 61 7.931 -6.494 0.590 1.00 50.11 H +ATOM 993 HA ALA A 61 6.366 -6.606 -1.656 1.00 63.40 H +ATOM 994 HB1 ALA A 61 6.757 -4.206 0.174 1.00 64.32 H +ATOM 995 HB2 ALA A 61 5.674 -5.569 0.455 1.00 72.00 H +ATOM 996 HB3 ALA A 61 5.373 -4.475 -0.893 1.00 3.20 H +ATOM 997 N THR A 62 7.393 -5.383 -3.578 1.00 12.23 N +ATOM 998 CA THR A 62 7.754 -4.599 -4.761 1.00 62.13 C +ATOM 999 C THR A 62 6.753 -3.437 -4.911 1.00 74.50 C +ATOM 1000 O THR A 62 5.599 -3.638 -5.324 1.00 34.21 O +ATOM 1001 CB THR A 62 7.745 -5.481 -6.053 1.00 61.43 C +ATOM 1002 OG1 THR A 62 8.586 -6.632 -5.865 1.00 32.31 O +ATOM 1003 CG2 THR A 62 8.225 -4.691 -7.288 1.00 21.33 C +ATOM 1004 H THR A 62 6.933 -6.228 -3.712 1.00 13.52 H +ATOM 1005 HA THR A 62 8.760 -4.204 -4.617 1.00 34.20 H +ATOM 1006 HB THR A 62 6.731 -5.822 -6.233 1.00 41.32 H +ATOM 1007 HG1 THR A 62 8.032 -7.406 -5.713 1.00 24.01 H +ATOM 1008 HG21 THR A 62 7.579 -3.837 -7.453 1.00 13.32 H +ATOM 1009 HG22 THR A 62 8.199 -5.331 -8.161 1.00 52.44 H +ATOM 1010 HG23 THR A 62 9.240 -4.344 -7.134 1.00 31.02 H +ATOM 1011 N ILE A 63 7.193 -2.235 -4.513 1.00 62.55 N +ATOM 1012 CA ILE A 63 6.368 -1.018 -4.523 1.00 72.53 C +ATOM 1013 C ILE A 63 6.946 -0.032 -5.545 1.00 40.43 C +ATOM 1014 O ILE A 63 8.108 0.355 -5.447 1.00 44.44 O +ATOM 1015 CB ILE A 63 6.332 -0.400 -3.070 1.00 52.40 C +ATOM 1016 CG1 ILE A 63 5.741 -1.456 -2.077 1.00 22.12 C +ATOM 1017 CG2 ILE A 63 5.525 0.931 -3.023 1.00 31.21 C +ATOM 1018 CD1 ILE A 63 6.035 -1.220 -0.619 1.00 52.01 C +ATOM 1019 H ILE A 63 8.108 -2.153 -4.166 1.00 61.44 H +ATOM 1020 HA ILE A 63 5.347 -1.284 -4.809 1.00 3.52 H +ATOM 1021 HB ILE A 63 7.356 -0.179 -2.775 1.00 65.24 H +ATOM 1022 HG12 ILE A 63 4.667 -1.473 -2.176 1.00 60.44 H +ATOM 1023 HG13 ILE A 63 6.126 -2.440 -2.325 1.00 3.31 H +ATOM 1024 HG21 ILE A 63 5.972 1.652 -3.698 1.00 22.24 H +ATOM 1025 HG22 ILE A 63 5.538 1.331 -2.019 1.00 4.24 H +ATOM 1026 HG23 ILE A 63 4.501 0.748 -3.323 1.00 30.03 H +ATOM 1027 HD11 ILE A 63 5.624 -2.032 -0.041 1.00 3.42 H +ATOM 1028 HD12 ILE A 63 5.587 -0.290 -0.301 1.00 54.23 H +ATOM 1029 HD13 ILE A 63 7.104 -1.177 -0.468 1.00 33.51 H +ATOM 1030 N ARG A 64 6.119 0.346 -6.528 1.00 73.11 N +ATOM 1031 CA ARG A 64 6.498 1.223 -7.642 1.00 11.12 C +ATOM 1032 C ARG A 64 6.334 2.679 -7.191 1.00 71.54 C +ATOM 1033 O ARG A 64 5.209 3.179 -7.075 1.00 3.44 O +ATOM 1034 CB ARG A 64 5.611 0.927 -8.887 1.00 50.44 C +ATOM 1035 CG ARG A 64 5.714 -0.519 -9.430 1.00 61.44 C +ATOM 1036 CD ARG A 64 7.141 -0.903 -9.876 1.00 53.01 C +ATOM 1037 NE ARG A 64 7.194 -2.243 -10.491 1.00 14.33 N +ATOM 1038 CZ ARG A 64 8.311 -2.981 -10.644 1.00 42.05 C +ATOM 1039 NH1 ARG A 64 9.499 -2.529 -10.227 1.00 73.22 N +ATOM 1040 NH2 ARG A 64 8.232 -4.165 -11.235 1.00 53.23 N +ATOM 1041 H ARG A 64 5.195 0.075 -6.454 1.00 51.34 H +ATOM 1042 HA ARG A 64 7.542 1.034 -7.892 1.00 14.11 H +ATOM 1043 HB2 ARG A 64 4.571 1.109 -8.626 1.00 64.44 H +ATOM 1044 HB3 ARG A 64 5.885 1.608 -9.686 1.00 40.01 H +ATOM 1045 HG2 ARG A 64 5.403 -1.202 -8.649 1.00 30.22 H +ATOM 1046 HG3 ARG A 64 5.042 -0.623 -10.276 1.00 31.22 H +ATOM 1047 HD2 ARG A 64 7.495 -0.180 -10.603 1.00 34.41 H +ATOM 1048 HD3 ARG A 64 7.796 -0.887 -9.011 1.00 30.15 H +ATOM 1049 HE ARG A 64 6.341 -2.615 -10.814 1.00 34.33 H +ATOM 1050 HH11 ARG A 64 9.573 -1.628 -9.788 1.00 34.40 H +ATOM 1051 HH12 ARG A 64 10.325 -3.089 -10.349 1.00 62.13 H +ATOM 1052 HH21 ARG A 64 7.349 -4.510 -11.564 1.00 45.31 H +ATOM 1053 HH22 ARG A 64 9.060 -4.728 -11.358 1.00 4.01 H +ATOM 1054 N LYS A 65 7.462 3.337 -6.904 1.00 55.55 N +ATOM 1055 CA LYS A 65 7.479 4.683 -6.324 1.00 72.41 C +ATOM 1056 C LYS A 65 7.905 5.692 -7.399 1.00 2.43 C +ATOM 1057 O LYS A 65 9.062 5.704 -7.816 1.00 23.42 O +ATOM 1058 CB LYS A 65 8.443 4.706 -5.106 1.00 60.12 C +ATOM 1059 CG LYS A 65 8.376 5.993 -4.255 1.00 54.24 C +ATOM 1060 CD LYS A 65 9.195 5.871 -2.950 1.00 13.41 C +ATOM 1061 CE LYS A 65 8.968 7.038 -1.985 1.00 35.42 C +ATOM 1062 NZ LYS A 65 9.707 6.834 -0.712 1.00 41.53 N +ATOM 1063 H LYS A 65 8.315 2.915 -7.126 1.00 32.22 H +ATOM 1064 HA LYS A 65 6.475 4.932 -5.982 1.00 63.32 H +ATOM 1065 HB2 LYS A 65 8.203 3.860 -4.464 1.00 13.21 H +ATOM 1066 HB3 LYS A 65 9.463 4.583 -5.461 1.00 43.42 H +ATOM 1067 HG2 LYS A 65 8.763 6.822 -4.840 1.00 33.11 H +ATOM 1068 HG3 LYS A 65 7.337 6.193 -4.002 1.00 21.31 H +ATOM 1069 HD2 LYS A 65 8.920 4.952 -2.443 1.00 42.01 H +ATOM 1070 HD3 LYS A 65 10.252 5.829 -3.202 1.00 53.53 H +ATOM 1071 HE2 LYS A 65 9.308 7.959 -2.449 1.00 3.35 H +ATOM 1072 HE3 LYS A 65 7.909 7.118 -1.767 1.00 24.44 H +ATOM 1073 HZ1 LYS A 65 10.729 6.773 -0.895 1.00 31.12 H +ATOM 1074 HZ2 LYS A 65 9.398 5.952 -0.256 1.00 40.42 H +ATOM 1075 HZ3 LYS A 65 9.532 7.625 -0.059 1.00 52.21 H +ATOM 1076 N THR A 66 6.938 6.492 -7.875 1.00 12.05 N +ATOM 1077 CA THR A 66 7.155 7.525 -8.909 1.00 22.33 C +ATOM 1078 C THR A 66 6.872 8.929 -8.328 1.00 41.33 C +ATOM 1079 O THR A 66 6.038 9.081 -7.424 1.00 50.40 O +ATOM 1080 CB THR A 66 6.235 7.229 -10.149 1.00 13.32 C +ATOM 1081 OG1 THR A 66 6.579 5.943 -10.691 1.00 24.34 O +ATOM 1082 CG2 THR A 66 6.332 8.296 -11.260 1.00 52.41 C +ATOM 1083 H THR A 66 6.029 6.380 -7.523 1.00 21.01 H +ATOM 1084 HA THR A 66 8.196 7.484 -9.241 1.00 53.43 H +ATOM 1085 HB THR A 66 5.205 7.183 -9.803 1.00 74.00 H +ATOM 1086 HG1 THR A 66 6.988 5.405 -10.002 1.00 51.01 H +ATOM 1087 HG21 THR A 66 7.356 8.379 -11.606 1.00 44.00 H +ATOM 1088 HG22 THR A 66 6.006 9.256 -10.874 1.00 13.21 H +ATOM 1089 HG23 THR A 66 5.699 8.018 -12.090 1.00 22.21 H +ATOM 1090 N GLY A 67 7.594 9.942 -8.843 1.00 30.00 N +ATOM 1091 CA GLY A 67 7.390 11.330 -8.451 1.00 64.41 C +ATOM 1092 C GLY A 67 8.036 11.661 -7.115 1.00 24.45 C +ATOM 1093 O GLY A 67 9.264 11.719 -7.027 1.00 11.31 O +ATOM 1094 H GLY A 67 8.286 9.734 -9.502 1.00 4.14 H +ATOM 1095 HA2 GLY A 67 7.824 11.966 -9.214 1.00 21.32 H +ATOM 1096 HA3 GLY A 67 6.326 11.541 -8.402 1.00 73.14 H +TER diff --git a/esm/source/examples/lm-design/README.md b/esm/source/examples/lm-design/README.md new file mode 100644 index 0000000000000000000000000000000000000000..5a92dc1271806ca5bd03bb8254735588548a1690 --- /dev/null +++ b/esm/source/examples/lm-design/README.md @@ -0,0 +1,32 @@ +# LM design examples + +This folder contains code for demonstration of protein design using a language model. The code was used to perform the two design tasks specified at the paper [Language models generalize beyond natural proteins +](https://www.biorxiv.org/content/10.1101/2022.12.21.521521v1). + + +## Notebook examples + +Refer to the two notebooks at this folder to run the fixed backbone and free generation design tasks. + + +## Shell examples + +To run the two design tasks from shell, do the following: + +1. First, install additional requirements: ```pip install -r additional_requirements.txt``` +2. Running Fixed backbone design: ```python -m lm_design task=fixedbb pdb_fn=$PWD/2N2U.pdb``` +3. Running Free generation design: ```python -m lm_design task=free_generation``` + +Notes: +Use the ```seed=``` flag to generate different designs, e.g: +```python -m lm_design task=free_generation seed=42``` + +Control generated length in free generation using ```free_generation_length=```, e.g: +```python -m lm_design task=free_generation free_generation_length=68``` + +Other, more advanced configurations can be observed at [config.yaml](conf/config.yaml) + + +## Paper data +The data from the preprint is available under [paper-data/](paper-data). +This includes designed sequences, their predicted structures, experimental validation results, linear projection for pairwise distance prediction, and details on dataset construction for model training. diff --git a/esm/source/examples/lm-design/__init__.py b/esm/source/examples/lm-design/__init__.py new file mode 100644 index 0000000000000000000000000000000000000000..e69de29bb2d1d6434b8b29ae775ad8c2e48c5391 diff --git a/esm/source/examples/lm-design/additional_requirements.txt b/esm/source/examples/lm-design/additional_requirements.txt new file mode 100644 index 0000000000000000000000000000000000000000..a700e2a8f9d6e2a4b251f3131bf9d2e17cacc92c --- /dev/null +++ b/esm/source/examples/lm-design/additional_requirements.txt @@ -0,0 +1,3 @@ +nltk +py3Dmol +hydra diff --git a/esm/source/examples/lm-design/conf/__init__.py b/esm/source/examples/lm-design/conf/__init__.py new file mode 100644 index 0000000000000000000000000000000000000000..e69de29bb2d1d6434b8b29ae775ad8c2e48c5391 diff --git a/esm/source/examples/lm-design/conf/config.yaml b/esm/source/examples/lm-design/conf/config.yaml new file mode 100644 index 0000000000000000000000000000000000000000..f0654731fe05b6db86e626f652ea66d651a24f11 --- /dev/null +++ b/esm/source/examples/lm-design/conf/config.yaml @@ -0,0 +1,62 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. +# +seed: 0 +num_seqs: 1 +test_mode: False +allow_missing_residue_coords: True +suppress_AA: 'C' +disable_cuda: False +cuda_device_idx: # Set to numberic value to override default GPU device used. +task: free_generation # fixedbb or free_generation +pdb_fn: # set as empty string when using free_generation +free_generation_length: 100 + +tasks: + free_generation: + num_iter: 170000 + resample_y_every: 3 + resample_y_temp: 1 + stage_fixedbb_args: ${tasks.fixedbb} + + + fixedbb: + num_iter: 170000 + + # Accept/Reject + accept_reject: + energy_cfg: + struct_w: 3 + LM_w: 2 + ngram_w: 1 + ngram_orders: [1,2,3] + temperature: + scheduler: StepLR + step_size: 10000 + gamma: 0.5 + initial: 8 + + + +# Hydra config +hydra: + job_logging: + formatters: + colorlog: + datefmt: "%m-%d %H:%M:%S" + handlers: + file: + class: logging.FileHandler + mode: w + filename: logging.l + console: + class: logging.StreamHandler + stream: ext://sys.stdout + + hydra_logging: + handlers: + console: + class: logging.StreamHandler + stream: ext://sys.stdout diff --git a/esm/source/examples/lm-design/fixed_backbone.ipynb b/esm/source/examples/lm-design/fixed_backbone.ipynb new file mode 100644 index 0000000000000000000000000000000000000000..3e7823b875fd2fe051f1b827831d4e9e4a6b2adb --- /dev/null +++ b/esm/source/examples/lm-design/fixed_backbone.ipynb @@ -0,0 +1,197 @@ +{ + "cells": [ + { + "cell_type": "markdown", + "id": "4f84941e", + "metadata": {}, + "source": [ + "# Fixed Backbone design from LM\n", + "\n", + "This notebook demonstrates the Fixed Backbone design task from the paper [Language models generalize beyond natural proteins\n", + "](https://www.biorxiv.org/content/10.1101/2022.12.21.521521v1).\n", + "\n", + "Given an input structure as .pdb file, the LM is used iteratively in an MCMC optimization to find a sequence that folds to that structure\n" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "d378b7f4-0792-446b-9e95-f7025bee5bec", + "metadata": {}, + "outputs": [], + "source": [ + "# First install additional dependencies\n", + "!pip install -r additional_requirements.txt\n" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "cfd13d6a", + "metadata": {}, + "outputs": [], + "source": [ + "# Imports\n", + "import os\n", + "import time\n", + "import hydra\n", + "import py3Dmol\n", + "from lm_design import Designer\n", + "\n", + "# Params\n", + "pdb_fn = os.getcwd() + '/2N2U.pdb'\n", + "seed = 0 # Use different seeds to get different sequence designs for the same structure\n", + "TASK = \"fixedbb\"" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "989996bf", + "metadata": {}, + "outputs": [], + "source": [ + "# Load hydra config from config.yaml\n", + "with hydra.initialize_config_module(config_module=\"conf\"):\n", + " cfg = hydra.compose(\n", + " config_name=\"config\", \n", + " overrides=[\n", + " f\"task={TASK}\", \n", + " f\"seed={seed}\", \n", + " f\"pdb_fn={pdb_fn}\", \n", + " # 'tasks.fixedbb.num_iter=100' # DEBUG - use a smaller number of iterations\n", + " ])" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "63178538", + "metadata": {}, + "outputs": [], + "source": [ + "# Create a designer from configuration\n", + "des = Designer(cfg, pdb_fn)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "86d25575", + "metadata": {}, + "outputs": [], + "source": [ + "\n", + "# Run the designer\n", + "start_time = time.time()\n", + "des.run_from_cfg()\n", + "print(\"finished after %s hours\", (time.time() - start_time) / 3600)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "d6d9f742", + "metadata": {}, + "outputs": [], + "source": [ + "print(\"Output seq:\", des.output_seq)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "ba6c8c66", + "metadata": {}, + "outputs": [], + "source": [ + "\n", + "# Fold output with ESMFold API\n", + "output_seq = des.output_seq\n", + "# Fold with api:\n", + "# curl -X POST --data \"GENGEIPLEIRATTGAEVDTRAVTAVEMTEGTLGIFRLPEEDYTALENFRYNRVAGENWKPASTVIYVGGTYARLCAYAPYNSVEFKNSSLKTEAGLTMQTYAAEKDMRFAVSGGDEVWKKTPTANFELKRAYARLVLSVVRDATYPNTCKITKAKIEAFTGNIITANTVDISTGTEGSGTQTPQYIHTVTTGLKDGFAIGLPQQTFSGGVVLTLTVDGMEYSVTIPANKLSTFVRGTKYIVSLAVKGGKLTLMSDKILIDKDWAEVQTGTGGSGDDYDTSFN\" https://api.esmatlas.com/foldSequence/v1/pdb/\n", + "import requests\n", + "import json\n", + "url = 'https://api.esmatlas.com/foldSequence/v1/pdb/'\n", + "r = requests.post(url, data=output_seq)\n", + "output_struct = r.text\n", + "\n" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "d5c06ab3", + "metadata": {}, + "outputs": [], + "source": [ + "# Visualize output structure\n", + "view = py3Dmol.view(width=800, height=800)\n", + "view.addModel(output_struct, 'pdb')\n", + "view.setStyle({'cartoon': {'color': 'spectrum'}})\n", + "view.zoomTo()\n", + "view.show()\n" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "b7247225", + "metadata": {}, + "outputs": [], + "source": [ + "des.x_logits.shape" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "d8e5c184", + "metadata": {}, + "outputs": [], + "source": [ + "# Visualize wild type structure\n", + "wt_struct_file = pdb_fn\n", + "view = py3Dmol.view(width=800, height=800)\n", + "view.addModel(open(wt_struct_file).read(), 'pdb')\n", + "view.setStyle({'cartoon': {'color': 'spectrum'}})\n", + "view.zoomTo()\n", + "view.show()" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "222ec344", + "metadata": {}, + "outputs": [], + "source": [] + } + ], + "metadata": { + "kernelspec": { + "display_name": "Python 3 (ipykernel)", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.7.12" + }, + "vscode": { + "interpreter": { + "hash": "5502aca739f2549ad2771378ffc455b2bbb8b06f1a91617971f7097758a3cf84" + } + } + }, + "nbformat": 4, + "nbformat_minor": 5 +} diff --git a/esm/source/examples/lm-design/free_generation.ipynb b/esm/source/examples/lm-design/free_generation.ipynb new file mode 100644 index 0000000000000000000000000000000000000000..ef9b65a43fb7ed7d5c01f183c146e3a0af3690e2 --- /dev/null +++ b/esm/source/examples/lm-design/free_generation.ipynb @@ -0,0 +1,169 @@ +{ + "cells": [ + { + "cell_type": "markdown", + "id": "e1a1c491", + "metadata": {}, + "source": [ + "# Free Generation design\n", + "\n", + "This notebook demonstrates the Free Generation design task from the paper [Language models generalize beyond natural proteins\n", + "](https://www.biorxiv.org/content/10.1101/2022.12.21.521521v1).\n", + "\n", + "Given an input sequence length, the design code activates the language model and the linear projection structure head alternatingly to generate a likely sequence and structure." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "5f76a438-3afd-4096-ba36-eb9bee90f08a", + "metadata": {}, + "outputs": [], + "source": [ + "# First install additional dependencies\n", + "!pip install -r additional_requirements.txt" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "59549997", + "metadata": {}, + "outputs": [], + "source": [ + "# Imports\n", + "import os\n", + "import time\n", + "import hydra\n", + "import py3Dmol\n", + "from lm_design import Designer\n", + "\n", + "# Params\n", + "seed = 0 # Use different seeds to get different sequence results\n", + "free_generation_length = 100\n", + "TASK = \"free_generation\"" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "8e27bf90", + "metadata": {}, + "outputs": [], + "source": [ + "# Load hydra config from config.yaml\n", + "with hydra.initialize_config_module(config_module=\"conf\"):\n", + " cfg = hydra.compose(\n", + " config_name=\"config\", \n", + " overrides=[\n", + " f\"task={TASK}\", \n", + " f\"seed={seed}\", \n", + " f\"free_generation_length={free_generation_length}\", \n", + " # 'tasks.free_generation.num_iter=100' # DEBUG - use a smaller number of iterations\n", + " ])" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "a95fbfb2", + "metadata": {}, + "outputs": [], + "source": [ + "# Create a designer from configuration\n", + "des = Designer(cfg)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "e92e577b", + "metadata": {}, + "outputs": [], + "source": [ + "\n", + "# Run the designer\n", + "start_time = time.time()\n", + "des.run_from_cfg() \n", + "print(\"finished after %s hours\", (time.time() - start_time) / 3600)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "fb4d9456", + "metadata": {}, + "outputs": [], + "source": [ + "print(\"Output seq:\", des.output_seq)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "12229064", + "metadata": {}, + "outputs": [], + "source": [ + "# Fold output with ESMFold API\n", + "output_seq = des.output_seq\n", + "# Fold with api:\n", + "# curl -X POST --data \"GENGEIPLEIRATTGAEVDTRAVTAVEMTEGTLGIFRLPEEDYTALENFRYNRVAGENWKPASTVIYVGGTYARLCAYAPYNSVEFKNSSLKTEAGLTMQTYAAEKDMRFAVSGGDEVWKKTPTANFELKRAYARLVLSVVRDATYPNTCKITKAKIEAFTGNIITANTVDISTGTEGSGTQTPQYIHTVTTGLKDGFAIGLPQQTFSGGVVLTLTVDGMEYSVTIPANKLSTFVRGTKYIVSLAVKGGKLTLMSDKILIDKDWAEVQTGTGGSGDDYDTSFN\" https://api.esmatlas.com/foldSequence/v1/pdb/\n", + "import requests\n", + "import json\n", + "url = 'https://api.esmatlas.com/foldSequence/v1/pdb/'\n", + "r = requests.post(url, data=output_seq)\n", + "output_struct = r.text\n" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "e516f069", + "metadata": {}, + "outputs": [], + "source": [ + "# Visualize output structure\n", + "view = py3Dmol.view(width=800, height=800)\n", + "view.addModel(output_struct, 'pdb')\n", + "view.setStyle({'cartoon': {'color': 'spectrum'}})\n", + "view.zoomTo()\n", + "view.show()" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "c1c9a0f0", + "metadata": {}, + "outputs": [], + "source": [] + } + ], + "metadata": { + "kernelspec": { + "display_name": "Python 3.7.12 ('esm-IF_py37')", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.7.12" + }, + "vscode": { + "interpreter": { + "hash": "5502aca739f2549ad2771378ffc455b2bbb8b06f1a91617971f7097758a3cf84" + } + } + }, + "nbformat": 4, + "nbformat_minor": 5 +} diff --git a/esm/source/examples/lm-design/lm_design.py b/esm/source/examples/lm-design/lm_design.py new file mode 100644 index 0000000000000000000000000000000000000000..b578ad96c9499ce706091aa03a4271039defdcf7 --- /dev/null +++ b/esm/source/examples/lm-design/lm_design.py @@ -0,0 +1,456 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + + +# core +import logging +import os +import sys +import time + +from omegaconf import DictConfig +import hydra +import os +from pathlib import Path +import sys +import time +import logging + +import numpy as np +from omegaconf import DictConfig, OmegaConf +import torch +import torch.nn.functional as F + +# make sure script started from the root of the this file +assert Path.cwd().name == 'lm-design', 'Please run this script from examples/lm-design/' +sys.path.append('../../') +from esm.data import Alphabet + +from utils.scheduler import SchedulerSpec, to_scheduler, set_scheduler_repo +import utils.pdb_loader as pdb_loader +from utils.loss import get_cce_loss +from utils.lm import lm_marginal +from utils.masking import assert_valid_mask +from utils.sampling import ( + set_rng_seeds, +) +from utils.constants import COORDS_ANGLE_NAMES, COORDS4D_NAMES +import utils.struct_models as struct_models +from utils.free_generation import stage_free_generation +from utils.fixedbb import stage_fixedbb +from utils.lm import WrapLmEsm + +from utils.tensor import ( + assert_shape, +) +from utils import ngram as ngram_utils + +logger = logging.getLogger(__name__) # Hydra configured +os.environ['MKL_THREADING_LAYER'] = 'GNU' + + +class Designer: + cutoff_dist = 8 + LOGITS_LARGE = 100 + standard_AA = 'LAGVSERTIDPKQNFYMHWC' + + ########################################## + # Inits + ########################################## + def __init__( + self, + cfg, + target_pdb_path=None, + device=None + ): + ## Initialize models + if device: + self.device = device + else: + use_cuda = torch.cuda.is_available() and not cfg.disable_cuda + device_idx = f":{cfg.cuda_device_idx}" if cfg.get('cuda_device_idx') else "" + self.device = torch.device(f'cuda{device_idx}' if use_cuda else 'cpu') + SEED_SENTINEL = 1238 + self.seed = cfg.seed + SEED_SENTINEL + self.cfg = cfg + self.allowed_AA = ''.join(AA for AA in self.standard_AA if ( + ('suppress_AA' not in self.cfg) or (not AA in self.cfg.suppress_AA))) + + self._init_models() + if target_pdb_path is None: + # eg notarget-L70 + target_pdb_path = 'notarget-L100' + self._init_no_target(cfg.free_generation_length) + else: + target_pdb_path = Path(target_pdb_path) + self._init_target(target_pdb_path) + + set_rng_seeds(self.seed) + self.schedulers = {} # reset schedulers + self.resuming_stage = False + self.init_sequences(cfg.num_seqs) + + torch.backends.cudnn.benchmark = True # Slightly faster runtime for optimization + logger.info("Finished Designer init") + + def _init_models(self): + self.vocab = Alphabet.from_architecture('ESM-1b') + self.vocab_mask_AA = torch.BoolTensor( + [t in self.allowed_AA for t in self.vocab.all_toks] + ).to(self.device) + self.vocab_mask_AA_idx = torch.nonzero(self.vocab_mask_AA).squeeze() + + self.struct_model, self.pdb_loader_params = struct_models.load( + self.vocab, + ) + self.LM = WrapLmEsm(self.struct_model.lm, self.vocab) + + # 4. Common model settings + def apply_common_settings(model): + model.to(self.device) + model.eval() + # No grads for models + for p in model.parameters(): + p.requires_grad = False + return model + + self.LM = apply_common_settings(self.LM) + self.struct_model = apply_common_settings(self.struct_model) + + def encode(self, seq_raw, onehot=True): + device = self.device + if isinstance(seq_raw, list): + seq_enc = [[self.vocab.get_idx(c) for c in seq] + for seq in seq_raw] + else: + seq_enc = [self.vocab.get_idx(c) for c in seq_raw] + seq_enc = torch.LongTensor(seq_enc) + if onehot: + seq_enc = F.one_hot(seq_enc, len(self.vocab)).float() + return seq_enc.to(device) + + def decode(self, seq_enc, onehot=True): + if onehot: + seq_enc = seq_enc.argmax(-1) + # for seq in seq_enc.view(-1, seq_enc. + assert seq_enc.dim() == 2 + # Must do cpu conversion here! + # Or else pytorch runtime will do it O(L) times and incur a very + # large slowdown. + seq_enc = seq_enc.cpu() + seqs = [ + ''.join([self.vocab.get_tok(c) for c in _seq]) for _seq in seq_enc + ] + return seqs + + def _init_no_target(self, L): + ## Initialize target and wt_seq + self.L = self.seqL = L + self.wt_metrics = {} + self.wt_seq = None + self.target_no_angles = False + + # Assume naive positional indexing, to allow calling struct_pred. + self.pos_idx = torch.arange(self.L).long()[None,].to(self.device) + # Valid contacts indicate positions that had no contact in the pdb file of the protein to + # ignore. No target, so everything is valid. + self.valid_contacts = torch.ones(self.L, self.L).bool().to(self.device) + + def _init_target(self, pdb_path): + ## Initialize target and wt_seq + assert pdb_path.suffix == ".pdb" + self.target_pdb_path = pdb_path + + self.pdb_id = Path(pdb_path).stem + self.target_data = pdb_loader.loader( + pdb_path=pdb_path, + params=self.pdb_loader_params, + set_diagonal=True, + allow_missing_residue_coords=self.cfg.allow_missing_residue_coords) + self.target_xyz = torch.tensor(self.target_data['xyz']).to(self.device) + self.pos_idx = torch.tensor(self.target_data['idx']).long()[None,].to(self.device) + self.coords = torch.tensor(self.target_data['coords6d']).long()[None,].to(self.device) + + self.wt_seq_raw = self.target_data['fullseq'][0] + self.wt_seq = self.encode(self.wt_seq_raw).unsqueeze(0) # B x L x K + self.seqL = self.L = len(self.wt_seq_raw) + self.target_distancemap = torch.from_numpy(self.target_data["dist"]) + self.target_contacts = (self.target_distancemap < self.cutoff_dist).to(self.device) + self.target_no_contacts = ~self.target_contacts + # Mark for contacts that have no nan distance values in the distance map + self.valid_contacts = torch.from_numpy(self.target_data['dist'] == self.target_data['dist']).to(self.device) + self.target_contacts &= self.valid_contacts + self.target_no_contacts &= self.valid_contacts + self.target_no_angles = self.target_data["no_angles"] + + logger.info(f'Initialized target {self.pdb_id} of length {self.seqL}') + logger.info(f'Wildtype sequence:\n{self.wt_seq_raw}') + + def init_sequences(self, num_seqs): + assert num_seqs == 1, "Only 1 sequence design in parallel supported for now." + self.B = B = self.num_seqs = num_seqs + + K = len(self.vocab) + AA_indices = torch.arange(K, device=self.device)[self.vocab_mask_AA] + bt = torch.from_numpy(np.random.choice(AA_indices.cpu().numpy(), size=(B, self.L))).to(self.device) + self.x_seqs = F.one_hot(bt,K).float() + self.init_seqs = self.x_seqs.clone() + + ########################################## + # Losses + ########################################## + def calc_sequence_loss(self, x_seqs, LM_losses={'CE_x_pLM': 1.0}, mask=None): + """ + Calculate pLM (LM output probabilities) based on mask-1-out over all positions. + Calculate seq_losses and combine according to weights in LM_losses. + Args: + x_seqs (torch.float32): [B, L, K] + Returns: + LM_loss (torch.float32): [B] + LM_out_logprobs (torch.float32): [B, L, K] + logging_dict: {other_metrics: torch.float32 [B]} + """ + B, L, K = x_seqs.shape + if mask is None: + mask = torch.ones(B, L, 1, device=self.device).bool() + n = assert_valid_mask(mask, x_seqs) + + LM_out_logprobs = lm_marginal(self.LM, x_seqs, mask=mask) + + # For loss calculations, only calculate based on the portion in `mask`. + x_seqs_masked = x_seqs.masked_select(mask).reshape(B, n, K) + losses = { + 'CE_x_pLM': -(x_seqs_masked * LM_out_logprobs).sum(-1).mean(-1), + } + LM_loss = sum(w * losses[name] for name, w in LM_losses.items()) + + return LM_loss, LM_out_logprobs, losses + + def calc_ngram_loss(self, x_seqs, ngram_orders=[1,2,3,4]): + B = x_seqs.size(0) + ngram_loss = torch.zeros(B).to(x_seqs) + seqs = self.decode(x_seqs) + for order in ngram_orders: + for i in range(len(seqs)): + ngram_loss[i] += ngram_utils.compute_kl_div(seqs[i], order) + return ngram_loss # [B] + + def calc_structure_loss(self, x_seq, temp_struct=None): + """Maps x_seq to the structure loss""" + B, L, K = x_seq.shape + + res_preds = self.struct_model(x_seq) + + if temp_struct is not None: + # Apply temp to res_preds output + for coord in COORDS4D_NAMES: + res_preds[f'{coord}_logits'] /= temp_struct + res_preds[f'p_{coord}'] = res_preds[f'{coord}_logits'].softmax(-1) + + # Mask handling + mask = torch.ones_like(self.coords[:, 0, :, :]).bool() + target_pos_mask = self.target_contacts[None] # [1, L, L] + target_neg_mask = self.target_no_contacts[None] # [1, L, L] + target_pos_mask &= mask + target_neg_mask &= mask + # The below is also: self.valid_contacts & mask + target_all_mask = target_pos_mask | target_neg_mask + + loss_dict = {} + targets = ['dist'] + if not self.target_no_angles: + targets += COORDS_ANGLE_NAMES + for i, targetname in enumerate(targets): + target = self.coords[:, i, :, :] + if target.size(0) == 1: + res_preds_B = res_preds['p_dist'].shape[0] + target = target.repeat(res_preds_B, 1, 1) + else: + assert_shape(target, B, L, L) + + + loss_dict[f'{targetname}_cce'] = get_cce_loss(res_preds[f'p_{targetname}'], target, target_all_mask) + cce_pos = get_cce_loss(res_preds[f'p_{targetname}'], target, target_pos_mask) + cce_neg = get_cce_loss(res_preds[f'p_{targetname}'], target, target_neg_mask) + loss_dict[f'{targetname}_cce_norm_avg'] = (cce_pos + cce_neg) / 2 + loss_dict[f'{targetname}_cce_pos'] = cce_pos + + CHOSEN_LOSSES = ['dist_cce_pos'] # Worked best in our experiments + total_loss = sum(loss_dict[k] for k in CHOSEN_LOSSES) + + return total_loss, loss_dict + + def calc_total_loss( + self, + x, + mask, + LM_w, + struct_w, + ngram_w, ngram_orders, + temp_struct=None): + """ + Easy one-stop-shop that calls out to all the implemented loss calculators, + aggregates logs, and weights total_loss. + + As a refresher: + calc_sequence_loss: + calculates \sum log p(x_i|x_\i) for i in {set bits in mask}. + If mask is all ones, this is equal to Pseudo-log-likelihood. + NOTE: every position in mask is masked *separately* + Therefore, there will be multiple forward passes of the LM. + calc_structure_loss: + calculates p(y|x) + calc_ngram_loss: + calculates p_ngram(x) + """ + + if mask is not None: + assert_valid_mask(mask, x=x) + logs = {} + total_loss = torch.zeros(x.size(0)).to(x) + if LM_w: + lm_m_nlls, _, lm_loss_dict = self.calc_sequence_loss(x, mask=mask) + lm_m_nlls *= LM_w / self.L + total_loss += lm_m_nlls + logs['lm_loss'] = lm_m_nlls + logs.update(lm_loss_dict) + if struct_w: + struct_m_nlls, struct_loss_dict = self.calc_structure_loss(x, temp_struct=temp_struct) + struct_m_nlls *= struct_w + total_loss += struct_m_nlls + logs['struct_loss'] = struct_m_nlls + logs.update(struct_loss_dict) + if ngram_w: + ngram_m_nlls = self.calc_ngram_loss(x, ngram_orders=ngram_orders) + ngram_m_nlls *= ngram_w + total_loss += ngram_m_nlls + logs['ngram_loss'] = ngram_m_nlls + + return total_loss, logs # [B], Dict[str:[B]] + + + ########################################## + # YAML Execution + ########################################## + + def run_from_cfg(self): + """ + Main run-loop for the Designer. Runs a relevant design procedure from the config. + """ + logger.info(f'Designing sequence for task: {self.cfg.task}') + + design_cfg = self.cfg.tasks[self.cfg.task] + if self.cfg.task == 'fixedbb': + stage_fixedbb(self, design_cfg) + elif self.cfg.task == 'free_generation': + stage_free_generation(self, **design_cfg) + else: + raise ValueError(f'Invalid task: {self.cfg.task}') + + logger.info(f'Final designed sequences:') + for seq in self.decode(self.x_seqs): + logger.info(seq) + self.output_seq = self.decode(self.x_seqs)[0] + + def init_schedulers_from_cfg(self, cfg: DictConfig): + """ + Similar to init_schedulers, but expects a stage-specific DictConfig. + Populates self.schedulers with dotlist key. + (Simplifies later OmegaConf accesses) + Example: + cfg = { + num_iter: 10, + sub_cfg: { + my_sched: { + scheduler: CosineAnnealingLR + initial: 1e-2 + T_max: 200}}} + Effect: + self.schedulers['sub_cfg.my_sched'] = + """ + def walk_cfg(d, parent_key='', sep='.'): + from collections.abc import MutableMapping + for k, v in d.items(): + new_key = parent_key + sep + k if parent_key else k + yield (new_key, v) + if isinstance(v, MutableMapping): + yield from walk_cfg(v, new_key, sep=sep) + + from typing import Optional, Dict, List, Any, Union + def is_sspec(maybe_sspec: Union[SchedulerSpec, Any]): + infer_from_key = (isinstance(maybe_sspec, DictConfig) + and maybe_sspec.get('scheduler', None) is not None) + # infer_from_type = OmegaConf.get_type(maybe_sspec) is SchedulerSpec + return infer_from_key + + if not self.resuming_stage: + for name, maybe_sspec in walk_cfg(cfg, sep='.'): + if is_sspec(maybe_sspec): + assert not name in self.schedulers, f"Trying to re-register {name}" + self.schedulers[name] = to_scheduler(maybe_sspec) + + def gen_step_cfg(self, cfg): + """ + Replace schedulers in a cfg with step-specific values. + Make sure to call `init_schedulers_from_cfg(cfg)` first! + Uses Designer state: + - self.schedulers + """ + step_cfg = cfg.copy() + for name, sched in self.schedulers.items(): + if OmegaConf.select(step_cfg, name) is not None: + OmegaConf.update(step_cfg, name, sched(), merge=False) + return step_cfg + + def stepper(self, iterable, update_schedulers=True, cfg=None): + self.init_schedulers_from_cfg(cfg) + + for local_step in iterable: + yield local_step, self.gen_step_cfg(cfg) + + if update_schedulers: + self.update_schedulers() + + def update_schedulers(self): + for s in self.schedulers.values(): + try: + s.step() + except AttributeError: + pass # constants: dummy lambda + + def init_schedulers(self, **kwargs): + """ + Schedulers (always stage-specific) are initialized according to SchedulerSpec, + and depend on global_step + Optionally wrapping an optimizer class with single param group. + Stores the schedulers in self._schedulers + Returns: + functions which return the current value for each + """ + set_scheduler_repo(self.cfg.get('schedulers', {})) + for name, sspec in kwargs.items(): + assert not name in self.schedulers, f"Trying to re-register {name}" + self.schedulers[name] = to_scheduler(sspec) + assert sys.version_info >= (3, 6), "py>=3.6 preserve kwarg and dict order see PEP468" + return [self.schedulers[name] for name in kwargs] + + +@hydra.main(config_path="conf/", config_name="config") +def main(cfg: DictConfig) -> None: + args_no_spaces = [arg.replace(" ", "") for arg in sys.argv[1:]] + logger.info(f"Running with args: {' '.join(args_no_spaces)}") + + pdb_fn = cfg.pdb_fn + logger.info(f'Starting to optimize seq for {pdb_fn}') + + start_time = time.time() + des = Designer(cfg, pdb_fn) + + des.run_from_cfg() + logger.info("finished after %s hours", (time.time() - start_time) / 3600) + + +if __name__ == "__main__": + main() # noqa pylint: disable=no-value-for-parameter diff --git a/esm/source/examples/lm-design/paper-data/README.md b/esm/source/examples/lm-design/paper-data/README.md new file mode 100644 index 0000000000000000000000000000000000000000..c7175291e6091e2668e4da9cdbdc0f9905be1458 --- /dev/null +++ b/esm/source/examples/lm-design/paper-data/README.md @@ -0,0 +1,74 @@ +Here we provide the data associated with the paper +["Language models generalize beyond natural proteins" (2022)](https://doi.org/10.1101/2022.12.21.521521) by +Robert Verkuil\*, Ori Kabeli\*, Yilun Du, Basile I. M. Wicky, Lukas F. Milles, Justas Dauparas, David Baker, Sergey Ovchinnikov, Tom Sercu, and Alexander Rives. + +## Free Generations (Section 3) +Designs from the Free Generations section of the paper (Section 3) along with their statistics and pdb files can be found at [free_generations_full.db](https://dl.fbaipublicfiles.com/fair-esm/examples/lm_design/free_generations_full.db) and can be loaded using: +``` +import pandas as pd; pd.read_sql('free_generations_full', 'sqlite:///free_generations_full.db') +``` + + +## Designs with wetlab validation (Section 2 and 3) +* [data.csv](./data.csv) - Load scalar data in `data.csv` with `pd.read_csv`. +* [data.hdf5](https://dl.fbaipublicfiles.com/fair-esm/examples/lm_design/design_lm_data_2022_v1.hdf5) +For long-form data, download `data.hdf5` from [this link](https://dl.fbaipublicfiles.com/fair-esm/examples/lm_design/design_lm_data_2022_v1.hdf5) and load with `pd.read_hdf`. +``` +# Design information +Design ID - {F,G}{0-267} unique identifier for each (LM or AlphaFold) design evaluated. 8 Nan values correspond to 8 ground truth sequences tested. +Experiment Name - Label for the testing pool to which the design / ground-truth sequence belongs. See Supplement; Section 1.6 for a full description of submitted sequences. These pools (minus ground-truth sequences) have experimental results shown in fig. S11. +Design Model - 228x LM, 20x AlphaFold, 20x AF+ngram, 8x Ground Truth. +Target ID - PDB ID of de novo target for all fixed backbone designs, 'Generation' for all free generations. +Sequence - Designed sequence + +# In Silico Evaluation +*AlphaFold predicted PDB file - Structure prediction from AlphaFold (5x pTM models, select best by pLDDT -> Amber Relax). +AlphaFold RMSD - (AlphaFold-predicted) RMSD to target backbone for fixed backbone designs, Nan for free generations +AlphaFold pLDDT - (AlphaFold-predicted) Avg pLDDT for the predicted structure + +# Experimental Evaluation +# Results from experimental testing. Final classifications are in the booleans: {Soluble, Success, Success+Monodisperse}. +Total Yield - Actual total soluble yield (in mg) from the 4x1mL prep. (Actual yield is closer to ~2x, we can only inject 1/2 of the total product onto the column.) +yield_per_Leq - Total Yield, adjusted to 1 L of culture equivalent +*Elution Volume (mL) - Array of x-values for plotting of the SEC trace. +*Chromatographic Absorbance at 280nm - Array of y-values for plotting of the SEC trace. +*Elution Volume (mL) (raw) - Raw version, data is not truncated, lengths may differ between rows. +*Chromatographic Absorbance at 280nm (raw) - Raw version, data is not truncated, lengths may differ between rows. +Soluble - Total Yield > 0.05 mg. +Success - Soluble and SEC peak at the expected elution volume. +Success+Monodisperse - SEC peak *only* at the expected elution volume. + +# Jackhmmer results +# See Supplement, Section 1.5 for verbose details. +# In short: Summary statistics of Jackhmmer searches (-n 1 --seed 0) of the designed sequence against UniRef90. Hits that were removed from ESM2's train set were removed from consideration here. See `.txt` files for ID's of these omitted sequences. +min Jackhmmer E-value - Minimum (best-domain) E-value +max Jackhmmer Seq-id (significant hits only) - Maximum Sequence identity over all significant (best domain E-value < 1) hits. +max Jackhmmer TM-score (top-10 hits only) - Maximum TM-score of the ≈top-10 (by best-domain E-value) hits. (Purging was applied after top-10, so the number considered may be slightly lower, counts were rarely reduced below 7). + +(* denotes long-form data only available in data.hdf5) +``` + +## `artificial_sequence_purge_ids.txt` +ID's of sequences removed due to being annotateed "artificial sequence" by the UniProt website when `2021_04` was the latest release. + +## `uniref90_jackhmmer_purge_ids.txt` +ID's of sequences removed by Jackhmmer search (`-n 1 --seed 0`) of UniRef90 when given the de novo target set as queries. + +## Minimal structure projection +A small new model head was constructed on top of ESM2, which is [this linear projection layer](https://dl.fbaipublicfiles.com/fair-esm/examples/lm_design/linear_projection_model.pt). +For a given sequence the projection measures the compatibility of the internal representations of the language model with a structure. +The linear projection layer is automatically downloaded when running the `lm_design` code. + +## Reference + +If using this work, please cite: +```bibtex +@article{verkuil2022language, + author={Robert Verkuil\*, Ori Kabeli\*, Yilun Du, Basile I. M. Wicky, Lukas F. Milles, Justas Dauparas, David Baker, Sergey Ovchinnikov, Tom Sercu, and Alexander Rives}, + title={Language models generalize beyond natural proteins}, + year={2022}, + journal={bioRxiv}, + note={bioRxiv 2022.12.21.521521}, + url={https://doi.org/10.1101/2022.12.21.521521}, +} +``` diff --git a/esm/source/examples/lm-design/paper-data/artificial_sequence_purge_ids.txt b/esm/source/examples/lm-design/paper-data/artificial_sequence_purge_ids.txt new file mode 100644 index 0000000000000000000000000000000000000000..beafd4dc0a7e72ab0be8443bc8399d42339dd5b2 --- /dev/null +++ b/esm/source/examples/lm-design/paper-data/artificial_sequence_purge_ids.txt @@ -0,0 +1,1027 @@ +F4ZNF8 +A0A2J8RBA3 +P62593 +G9F9U8 +P0A0C4 +A0A1D5R6J9 +Q8NFU1 +O35638 +P97793 +P03023 +P35125 +P08588 +A0A1Z1CGU0 +A3DJ78 +P03051 +C3TTS2 +A0A7S7YQ80 +A0A8A1QP70 +P00552 +C0IR82 +A0A6G8MV33 +A0A7G3QPU0 +C1IW73 +O21999 +A0A7S7YQ81 +B6ZLM4 +E9QNN1 +C3TTS5 +A0A8A1QPY2 +A0A6G8MVA3 +UPI000B4966E4 +UPI000CFA7FCD +UPI000219022D 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+17,F017,Fixed_Rd2_compare_AlphaFold_20,AlphaFold,6D0T,APDLDEHFAGKWTWVFVSQDGVSYTGTSTMRAVDGNVIQIDYTGHDSDGTPVTGGGYIHNNHPGRLHFVMAFSNGLVLEGWLTVVGDDTILVHMTSNTGRTYVGVFTRTDA,0.015506616586872708,3.876654146718177,False,False,False,0.9828828573226928,91.99622006352418,0.094,0.21621621621621623,0.90737 +18,F018,Fixed_Rd2_compare_AlphaFold_20,AlphaFold,6D0T,RPDLSTHLPGHYEWHFVSNDGYAFTGTVTMEVVDPNVIWMHYTGWDNNGTPLSGWGYFRDHHPEYYEFGMWMSNGYKFHGWVEFVDDNRIEVVARSNKDRIYSAVFTKHDP,0.004148435344812339,1.0371088362030847,False,False,False,0.6710172891616821,93.87439772382255,0.43,0.16216216216216217,0.44506 +19,F019,Fixed_Rd2_compare_AlphaFold_20,AlphaFold,6MRS,NSPAVMKVIEAVIQAVEGWPSTIHIIRWPHYHLIHIPGLTREQQAELLAVVAWASEAYGVPTWVHLHGNTVSILIFD,0.0067303889674713464,1.6825972418678365,False,False,False,0.4508427381515503,96.6509884001364,4.6,,0.58873 +20,F020,Fixed_Rd2_Distant_24,LM,6MRS,MSEKVLKALEEAENAVKEAGGSLSRSVSGDKVTLTITGLPSDVASKIEGKLREVGEKYGVPVEVSISGSTVTATFRV,0.20536458406256974,51.34114601564244,True,True,True,1.2931123971939087,90.93261409285294,0.58,0.3246753246753247,0.74641 +21,F021,Fixed_Rd2_Distant_24,LM,6D0T,MAKLSELLVGEYEITGKNAAGEPVTGTLKIEAVSDTEVKVSGTIKTKDGKEVPQSGSATVAADGTVTAERKLEDGRVVKSTSKPEGDKTLTTTSVLDDGSEIVEKGVRKAS,0.24740261117966605,61.85065279491651,True,False,False,2.7274112701416016,82.86246046516828,0.61,0.22522522522522523,0.78995 +22,F022,Fixed_Rd2_Distant_24,LM,6D0T,MSSVLDKVAGEYTVEGKDPQGNPITGSLKIEKKDEKTASISGKLKTPEGKEVPVSGEATVTSENKVEVKVKAEDGSEITLTGTLESDDTIKLSGTTKDGKPVELTAKRPKS,0.34486560568121266,86.21640142030317,True,True,False,2.518651247024536,86.09766403439173,0.24,0.35135135135135137,0.90266 +23,F023,Fixed_Rd2_Distant_24,LM,6CZJ,MTFVERLAGKYEGEAKNAAGEPVKVVLEITKEGDNKASVKLTITTKDGKTEELSGSATLESETKATVSLKTSDGQTVTLTVEKPSDSEIKVTGTAPDGSKIEGTLKKKS,0.2537102178201451,63.42755445503627,True,True,True,1.669878602027893,86.19851952337629,0.94,0.2018348623853211,0.38273 +24,F024,Fixed_Rd2_Motif_11,LM,6W3W,AGDEAAVKDVVTKLIEAENKRDAAGLKALVAPGAKIVEEGKTITGVDAFVKELEKEPKPTYTLGEVKVSGDTATVPVTETEDGKSEKGTVTLKKDGGKWVISEIKEE,0.28501657145748693,71.25414286437173,True,False,False,2.4170925617218018,89.54169269821487,2.3e-06,0.37383177570093457,0.7676 +25,F025,Fixed_Rd2_Motif_11,LM,6CZJ,MTLEEALAGTYKIEGKDAAGNPISGTSTITKEGEGKYSVVSEIKTPDGKVIKSSGSATVEKDGTVKAELTAENGQKLTVTLKVNADGSRDVTVTTSDGKTFTGKETRVK,0.24468233970059516,61.17058492514879,True,True,False,1.6262468099594116,87.99247793965945,0.002,0.28440366972477066,0.84723 +26,F026,Fixed_Rd2_Motif_11,LM,6CZJ,MTLEEKLVGEYSVSGKTPEGAEYTGKAKIEKAGENKYKVTWTTKNAEGKEVTSSGEATLKDDKTVELTITNPDGSKSTGTAVVKDADTREITFKGSDGQEIKETWKRVK,0.3977466139210023,99.43665348025057,True,True,False,1.337502360343933,88.70211181997347,0.0016,0.25688073394495414,0.84406 +27,F027,Fixed_Rd2_Motif_11,LM,6CZJ,MTVLDKLAGKYTLSGTGPDGKPVSGELTITKEGENKVSVERKITSPEGKETTEKGTATLKSDTEADVTLTAEDGSTVSATVKLESDSEISFTGKTKDGQEVKVTAKKAS,0.40438764010168293,101.09691002542073,True,True,False,1.4750990867614746,88.14754882966898,0.9,0.21100917431192662,0.81634 +28,F028,Fixed_Rd2_Motif_11,LM,6CZJ,MSLADKLVGEYTVSGKDAEGNEYSGTAKISKAGENKYTIEWTSTDKEGKPITLKGEATVKDDSTVEIKVTTEDGKEITGVQKVVSDTEREVTLTLPDGSVAVEKWTKKS,0.3733776066897868,93.34440167244671,True,True,True,1.5804373025894165,89.3412295564101,0.0025,0.23853211009174313,0.84063 +29,F029,Fixed_Rd2_Motif_11,LM,6CZJ,MSVLDALAGKYTVKGKNPDGSEYTGTAEITKKDDTTAAVSLTVTGADGKPVTLSGEAKLEGENKISSTLKTSDGREVKVVEELVSATERKVTITPPGGSPIVETWTKAS,0.2803780751152961,70.09451877882402,True,True,False,1.886478304862976,85.56625102495296,0.00015,0.29357798165137616,0.79837 +30,F030,Fixed_Rd2_Motif_11,LM,6D0T,MSSVLDKVAGEYEVSGKTPDGKPYKGTATITRVSDTEAKISWTSTPPEGKEIKLEGTAKESEPGKVTVTLKGEDGQEVTGTYTVNADGSLSATLTTKDGVKAEETWKKKAS,0.3798131326932491,94.95328317331229,True,True,False,2.5999600887298584,87.12063850277771,0.0004,0.3063063063063063,0.83537 +31,F031,Fixed_Rd2_Distant_24,LM,1QYS,MFRVKVTGTKDGKPVTEEYTASKPEDVVKAVGEVIKKLKEKGVTSATVEIEAESEKDLENAKRIVEGLLRAAGAKNVSVSLSGRKLTITATL,0.3427875797108305,85.69689492770763,True,True,True,1.807220816612244,89.89167015658074,2.2,,0.53858 +32,F032,Fixed_Rd2_Distant_24,LM,1QYS,MVKVVIKGTKDGKPVEKTLEASSLRDVGKLVRETVKELKDAGVSSVTVEVTAPSEKAAKIAENVAVNALKKAGAKDVTSKVEGNKVTITATL,0.9202675931650974,230.06689829127436,True,True,False,2.0360801219940186,92.28481875444518,5.9,,0.52215 +33,F033,Fixed_Rd2_compare_AlphaFold_20,AlphaFold,6MRS,RSPQVMRVIEEIAQAVQGWPVELHMIWGPDRVIVIIPHLTWPQQMELLAVVARASWELGVPTKVYIGGSTVIIIVDD,0.006731173414179127,1.6827933535447817,False,False,False,0.4216504096984863,97.22116813959614,1.7,,0.94281 +34,F034,Fixed_Rd2_Distant_24,LM,1QYS,MVRVKVTGTKDGKPVTIEGEASKPEDLKDVVAKAVEKLKEAGVTSATVEITAENEAQLSEVKKIVEEELRKAGAKNVSVSLEGKTLKVSGSF,0.33944966291032735,84.86241572758183,True,True,True,1.9140664339065552,89.98501265829073,0.9,0.22826086956521738,0.4941 +35,F035,Fixed_Rd2_Distant_24,LM,1QYS,MVKVTLTYTKDGKTVTETIEESDPSKAGEVIKKVVEKLKELKPTSVTVEITASSEDEAKNAENIVKAVLTGLGAKDVSVSREGSTVKISATF,0.4037276032258898,100.93190080647246,True,True,False,2.09683895111084,90.84441433223994,2.0,,0.6046 +36,F036,Fixed_Rd2_Distant_24,LM,1QYS,MVKLTITGTKDGKPVTKTVEVSSLEGLPSEIEKAVKELKDAGVTSVTAEVEAPDSATANVVARVLEATLRAAGAKDVQVSVSGSKVTVKASF,0.395968365097821,98.99209127445525,True,True,True,1.81305992603302,90.34497043231632,0.96,0.22826086956521738,0.48044 +37,F037,Fixed_Rd2_Distant_24,LM,1QYS,MVKLTLTYTTPEGTKTETVEVSSLEEAKEKIKAKVEELKSKGVTSVTVVIEAPSEDAVRVAENVARLVLSAAGAKDVKVSREGNKVTITATF,0.052453902269729735,13.113475567432435,True,False,False,1.5934504270553589,90.3361436031438,2.4,,0.55363 +38,F038,Fixed_Rd2_Distant_24,LM,1QYS,MVKYTLTATKDGKTVTKSGEASSLSEVPSEISKLLEELKKEGVTSATVVIEAPDEKTAENAKRVAEAVLKAAGAKDVSVKVEGNKVTITGTF,0.3282799016302957,82.06997540757392,True,True,True,1.724876880645752,90.52690170049704,0.78,0.2717391304347826,0.8638 +39,F039,Fixed_Rd2_Distant_24,LM,6CZJ,MTVLEKLAGKYEISGKSPEGEPVTGTSEITKEGDNKAKIVSTIKTKDGKEVKLSGTATVESDTKVSAPLTLEDGRKVTAEYTFVDADTVKVVITLDDGSKIEGTEKRVK,0.36725811471625625,91.81452867906407,True,True,True,1.2565298080444336,88.28953625778355,0.84,0.22935779816513763,0.76003 +40,F040,Fixed_Rd2_Distant_24,LM,6CZJ,MTVAEKLAGEYTVTGKNAAGQAVSGSSKITKVDATNYKVESTLTTPEGKPVTLSGTAKLESDTSAPIELKTEDGKTVKGTIKFEGADKRVVEVPGPDGGVLKETWTRKK,0.2979780984488259,74.49452461220648,True,True,True,1.509373664855957,86.41524649023813,0.81,0.1834862385321101,0.55789 +41,F041,Fixed_Rd2_Distant_24,LM,6CZJ,MSLEEKIAGKYEVSAPGPPGVTVTGTLEIKKEGENKYSVKGELVTPEGQKVPVEGSATLESETKATVKLKTSDGREITLTIEFKSDDEAVVSGTTPDGKPISGTAKRVK,0.07818634822978235,19.54658705744559,True,True,False,1.5739067792892456,86.4768208724314,0.0099,0.3211009174311927,0.74571 +42,F042,Fixed_Rd2_Distant_24,LM,6CZJ,MSDLDKIAGEYEVSGKSPEGEEIKGTLKVTKKDDKTVAVELELPGPDGKPVKASGTGTYDGGSKATVTVKDEEGNEVTLTITFKDADTAEIEGKDSEGQPIKLTAKRKK,0.43600475224699825,109.00118806174956,True,True,False,1.936157822608948,86.32997514021847,0.4,0.21100917431192662,0.82276 +43,F043,Fixed_Rd2_Distant_24,LM,6CZJ,MSFVEKLAGKYKVEVPGPPGLTISGTWEIKAEGENKASITSTTKDPTGKEVKVSGVLEKKSDTEAVGKITLPDGSSADVTVKLEGDDKLSVTAKNAAGQELKGTATRVK,0.1588073964687471,39.70184911718677,True,True,True,2.2209596633911133,85.67952096772032,0.83,0.25688073394495414,0.74244 +44,F044,Fixed_Rd2_Distant_24,LM,1QYS,MPTVKITGTKDGKPVTEEYTTSDPSEIKSIVEKKAKELKDSGVSSVTVEVTASSEGELREAQRVAENALRDAGLKNVSTRLEGNKLVISGSA,0.0994513461543207,24.862836538580176,True,True,False,2.0107052326202397,91.17856337372622,2.0,,0.82719 +45,F045,Fixed_Rd2_Motif_11,LM,6D0T,MKSLSEKLAGEYTLEGEAPGGAKITGKTVIKAVGENKFEVTSSVTDPSGKPVESKGTAELKGDKEIVATLTASDGSTATVTETVVSADERKVTITTKDGQKIEVVEKRVKK,0.13598994945441087,33.997487363602716,True,True,False,3.051065683364868,88.52513366461596,0.36,0.24324324324324326,0.8139 +46,F046,Fixed_Rd2_compare_AlphaFold_20,AlphaFold,6MRS,GSPKVWQVIWAILQATQGMGVTVHIIAHPHHYLIIIPGLTAEQQWILLHVVAQAAQLFGVPTWVHLEGGTVSILVFD,0.0055851279719760704,1.3962819929940176,False,False,False,0.3663604259490967,97.1495514547789,0.0045,0.2727272727272727,0.48785 +47,F047,Fixed_Rd2_compare_AlphaFold_20,AlphaFold,6MRS,VNPKVWKMIYSVIQATKGMGHHIHIHWYPHFFIIHIPGLTDAQYERIRQAVAQSAEQNGVETWLYWSGNTVTIIIFE,0.003687218919149328,0.9218047297873321,False,False,False,0.4571395814418793,95.11999800945894,2.7,,0.55457 +48,F048,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,6NUK,SYEFRVSVSVTVSDVPGILAWLEGLSATLKELEAGTPARIRETVRIDGGKVDLTIVAENAEPAVVSEIIGLLLPFVERYGGSLIIEY,0.397509175990901,99.37729399772526,True,False,False,0.6839452385902405,93.80271215881568,5.0,,0.49771 +49,F049,Fixed_Rd2_compare_LM_24,LM,5L33,MKPEEVVKKYIEALNKGDANAVKELLSSDVELTDVGQTLKGEKAAEFVAGLAKSGAKAEIKDLKVEGDKVTATVTITAGGKTTTSKDTFTVKDGKITKLEVSAS,0.39212291496487056,98.03072874121764,True,True,False,2.490266799926758,91.68561308298789,5.8e-08,0.40384615384615385,0.83014 +50,F050,Fixed_Rd2_compare_LM_24,LM,5L33,MSAKEVVEKYVAALNSGKPEDLKPLLADDVTLTDVGQELKGSDAVKFVEGLSKAGAKIELGEVSESGDTVTAPVTITAGGKTTKATDTFTVKDGKITKLEIKAS,0.06935968584639321,17.3399214615983,True,True,False,2.330277919769287,89.5547881916068,3.8e-06,0.3942307692307692,0.84532 +51,F051,Fixed_Rd2_compare_LM_24,LM,5L33,MSAKDVVNKYVEALNSGDPEKAASLYAENATVTDAGKTLTGKEIGEYLKGVAAGGAKLEVGEVKEEGDKVTAPVTITLPGQTIKAVDTFTVKDGKIVSSEFKAE,0.38402089919353116,96.00522479838278,True,True,False,1.8524878025054927,89.30061218432351,9.4e-10,0.40384615384615385,0.92595 +52,F052,Fixed_Rd2_compare_LM_24,LM,5L33,MSAKEVVEAYVKALNEGKPEDLKKVLADDVELTDVGQTLKGSDAVKFAEGLSKAGAKLEIKDISESGDTVTATVTITAGGKTTEAKDTFTVKDGKITKLVIEPK,0.6398325282794153,159.95813206985383,True,True,False,2.2361340522766118,90.44281855923052,2.4e-05,0.38461538461538464, +53,F053,Fixed_Rd2_compare_LM_24,LM,5L33,MSAKEVVTKYIEALNKGDAKAAGELLSPEVELTDVGQTLKGSDAVKFVEGLAKSGAKAELVSLEEKDGKVVATIKVTAGGKTVTSTDTFTVKDGKITKLEISSK,0.35495440722572474,88.73860180643119,True,True,False,1.9567445516586304,91.38719989078253,4.7e-06,0.36538461538461536,0.85161 +54,F054,Fixed_Rd2_compare_LM_24,LM,6D0T,MLKPEDLAGKTFEGKLTTKDGKEITGTVTIEKKGENEYSVKISGKDAEGKPVEVSGTAKLESETKAVVTLKDDKGNEVTATVERPEPGKIKVTVKASDGSEASGELTEKKS,0.3765251534916582,94.13128837291455,True,True,False,2.6787517070770264,84.5044350504976,0.064,0.32432432432432434,0.70066 +55,F055,Fixed_Rd2_compare_LM_24,LM,6D0T,MASLLEKIAGEYEISGKTPEGEEVSGTVTIKAKDDKTAEIEGKLKTKDGKEVPVKGSATVESENKVKVTLTTEDGQKVELEGEVKDENTIVLKGKTSDGKPVEATLKKKSS,0.5348707582648717,133.71768956621793,True,True,False,2.441730260848999,87.08570465817874,0.17,0.1891891891891892,0.9073 +56,F056,Fixed_Rd2_compare_LM_24,LM,6D0T,MASLAEKLVGEYTLSGQTPEGKPVSGTLTIKAAGDGKYEISGSAKDSEGKEVPVTGTAELKSDTEAVVTLTTKDGKTVTATVKVVDENKIEITGKDDAGNEVKLTGERKKS,0.1467424148581473,36.685603714536825,True,True,False,2.2758829593658447,85.9973229866832,0.01,0.3063063063063063,0.64224 +57,F057,Fixed_Rd2_compare_LM_24,LM,6D0T,MASLLDSVAGKYTFKVTTPEGVEITGELTITKKDDTTADVTGTAKTPDGKEVPVKGTVKLESETKATVELTLEDGSKITATIEKVDENTLKVSGKDAEGNEISGEAKRVSS,0.3781642452545014,94.54106131362535,True,True,False,2.1835381984710693,87.53634282677913,0.34,0.2882882882882883,0.73003 +58,F058,Fixed_Rd2_compare_LM_24,LM,6D0T,MASVLDKVAGEYTVKGKDPQGNEISGTVTIKKESDSKATVSAKLKTPEGKEIEAEGTAEDAGSGKYKVTLTTKDGQKITGEVEVTSENKAVFKGTTPDGKPVELTLEKKSS,0.2722799409457035,68.06998523642588,True,False,False,2.5545766353607178,86.77399146550304,0.043,0.25225225225225223,0.83274 +59,F059,Fixed_Rd2_compare_LM_24,LM,6MRS,MSEAVNKALEEIEKRVKELGGSISKSVSGDTVTLTITGLSPSDAEKLKPIVEEVGKKYGVPVTVKVEGNSVTATFRV,0.4146882077613797,103.67205194034493,True,True,True,1.2394684553146362,90.22297520345086,0.5,0.36363636363636365,0.56873 +60,F060,Fixed_Rd2_compare_LM_24,LM,6MRS,MDPRVQKVLDAVRAEVSKLGGSLSESVSGDTVTLTITGLSPSDVEKVKEAAKKAGEEAGVPVEVTVEGSTVKVTFRV,0.42795601432893304,106.98900358223327,True,True,True,1.0627379417419434,88.78233635603895,0.0086,0.33766233766233766,0.94273 +61,F061,Fixed_Rd2_compare_LM_24,LM,6MRS,MDPRVKAVLDAVRAEVEKLGGSLSESVSGDKVTLTITGLTEENAKKLKEILEAKGKELGVPVEVKVEGTTVTATFTV,0.06768315402819766,16.920788507049416,True,True,False,1.1077884435653689,88.68789417835325,1.4,,0.65477 +62,F062,Fixed_Rd2_compare_LM_24,LM,6MRS,MSEAVNKALEEIEKRVRELGGSLSRSVSGDKVTLTVTGLPPSAAEKLKDVVKEVGEKYGVPVEVSISGTTITATFRV,0.32934146863803615,82.33536715950903,True,True,True,1.1360328197479248,89.26651574507316,0.36,0.2597402597402597,0.78406 +63,F063,Fixed_Rd2_compare_LM_24,LM,6MRS,MSEAVNKALEEIEKRVKELGGSLSRSVSGDTVTLTITGLTPEVAEKLKPIVEEVGKKYGVPVTVKVEGNSITATFRV,0.34711303125744997,86.77825781436249,True,True,True,1.2481086254119873,89.66695531546407,0.38,0.33766233766233766,0.5774 +64,F064,Fixed_Rd2_compare_LM_24,LM,6NUK,MPTYTITVTGKPPSREAAEKLKAELEKRLEEIKKETGGSASLSISVSGDTVTATLTVSDPKPEVVNKVKEIVERVAGEYGLKVEVKG,0.38448925298207326,96.12231324551831,True,True,True,1.672995924949646,85.72934394680213,0.95,0.2413793103448276,0.38076 +65,F065,Fixed_Rd2_compare_LM_24,LM,6NUK,MPTYTITGTIKVPSREAAEKAVSEISSKLEELKKEAGGEVSVSASLSGDTLTVTATVKDAPPEVVNKVKEILKPIVEKYGGSFTVSG,0.27670878440403274,69.17719610100818,True,True,True,1.4940338134765625,86.68075073787664,1.1,,0.45283 +66,F066,Fixed_Rd2_compare_LM_24,LM,6NUK,MPTVTLKGTVKVPSREAAEKLVSELKSKAEEIAKETGGRVSVSASLSGDTLTITATVTDAPPEVVEKIKNAVKPIVEKYGGSLEVSG,0.3782618229632644,94.56545574081609,True,True,True,1.965891003608704,87.01459559497974,1.5,,0.69193 +67,F067,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,6NUK,SNEVTITLRFVTKEPAALDKRISGLIFGLRNLAAVTGPPIRVRVIKDGGRYEITVTVSDAPEYVVETILSWLRPLVEDEGGELTVNR,0.025522988182149688,6.380747045537422,False,False,False,0.6856326460838318,93.01342464445024,3.4,,0.72334 +68,F068,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,6NUK,SPTTTISVSFRVSAPDAVLRRLAWLKAELARIAAEGEYTIRLIIVYDGGRVRLTVTVSDPPGEVVEEIIGLLLPLVETSGGSLEIRP,0.014717887286131444,3.679471821532861,False,False,False,0.617400586605072,93.0615892190848,0.51,0.28735632183908044,0.59931 +69,F069,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,6NUK,SPKVTISGSFRSTEGEALDLQLERLKENLKEIEKGTGVRITTKIVKDGGRYGITITAVNSEPPVVAEILAMLRPLKETQGGSLRVSA,0.05544771673805695,13.861929184514237,True,False,False,0.7212327718734741,89.46671457519403,1.0,,0.717 +70,F070,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,6NUK,SPKTTIRISWKTSDLAATIGRLKNILKVLAELEASTDVKITGYVTINGGNVRFRVTVENPPESVVEYIIEILRPIVDSDGGSLEIEK,0.029373659480558863,7.343414870139716,False,False,False,0.6144019365310669,93.7152693065673,2.6,,0.72923 +71,F071,Fixed_Rd2_compare_AlphaFold_20,AlphaFold,6NUK,SRSFIIGVHVRTSELEGMKRWIQNLQANLQYLEAHSGHKIHMHVTMEDNDLSIIIIIHDWDAELVHRVIDMLVPLVQHHGGLLVIIP,0.0028960967350633005,0.7240241837658251,False,False,False,0.468681275844574,96.12428272083872,3.8,,0.58877 +72,F072,Fixed_Rd2_compare_AlphaFold_20,AlphaFold,6NUK,ENVVAIYIKYKTTHPMETLMRLQWLKGHLAWLAAHSDAPIYMYVHIKGNEVEILVIVRNWTPWLVMEIIWHLLPWVEEEGGELYIFL,0.0028035211157925325,0.7008802789481331,False,False,False,0.5145629644393921,95.31983353633112,3.0,,0.51107 +73,F073,Fixed_Rd2_compare_AlphaFold_20,AlphaFold,6NUK,SPKFIIVMSFKTDRPEETKLRLAWLKGWLKWLEAKTPAKINMYVKINDGNVFIMVTLINPQPEMIERVIWMLLPWKEEYGGSLYIFP,0.0015853388134483997,0.3963347033620999,False,False,False,0.4841421246528625,95.45712654746409,3.2,,0.50826 +74,F074,Fixed_Rd2_compare_AlphaFold_20,AlphaFold,6NUK,VPVVKISVAFWAEEPDAIRAWLRQFYNNLRALEANTDSTIHMYVVERRGWYAIWVEVYGYDEKLKEQIISMLLPIVERYGGSMQIED,0.006123649016661879,1.5309122541654696,False,False,False,0.4769626557826996,97.1155665975422,1.6,,0.50591 +75,F075,Fixed_Rd2_compare_AlphaFold_20,AlphaFold,6NUK,SKQVQISLAIRTTEPAPMARRIANFRADLERLKANSPMEAHLTVITNGGNIAMTVVLVDWDEEIVQRVIGMLLPWVNHYGGYMEYRP,0.012608951268734995,3.1522378171837486,False,False,False,0.4407394826412201,95.49964385694892,0.041,0.21839080459770116,0.52575 +76,F076,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,5L33,SEKLEVAYKFVRALEEGSPEELREVVPPKTTLVVGGKRYTGDGIGEYVENLARSGVEIKAESVREDGGPYVFDLRVSAGGNEFRVTLQITVKDGKLDTVVITGR,0.03433580815522718,8.583952038806796,False,False,False,0.6159579753875732,92.56226007687252,0.66,0.22115384615384615,0.50001 +77,F077,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,5L33,GKPLEIAEAFVKVLQAGDAEELKNVVSAPARMTVGGRKYEGKEIVSFVERLAENKVTVQKLSARREGGKYVVGLRVTKDGSTGLVLVTISVKNGELSEVIIETS,0.0195163450991353,4.879086274783825,False,False,False,0.6291195750236511,89.29584350313368,1.3,,0.82768 +78,F078,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,5L33,SPPEPKARAFVRALETGSPEEMKSILSPSTTLVVGGETYTGDQGVGLVERLKEARIKVKLLSWTKEGGAPIFRVRVSAGGSEIDYTISVEVTDGKVVNVVITGP,0.045617220559802565,11.404305139950642,False,False,False,1.501671552658081,93.55763168023591,0.13,0.18269230769230768,0.75454 +79,F079,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,5L33,SPEGEVAGRFVEALERGDPELLENVVSEGTTLVDGGRQYTGSSIVEYVKEIRESGTKVTRLSSYREGGAYVVPLKWTKDGAEFRVKATITVTDGKLTNVVIERP,0.01781002567547135,4.452506418867837,False,False,False,0.7932162880897522,94.82330797515212,0.034,0.28846153846153844,0.79219 +80,F080,Fixed_Rd2_compare_AlphaFold_20,AlphaFold,6MRS,SSPAKHKVIEAIAQAVQGMNVRLQIYEAPGYSIIYIPGLTFEQQLRLLAVVAQASHAFGVPTSVHLWGNTVMITVLD,0.01253226726272454,3.133066815681135,False,False,False,0.5121968984603882,95.97648053702224,1.4,,0.46478 +81,F081,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,5L33,SPKEAVVEDFVKALETGDASSLAGVVSEPVTGTVDGRTFKGKEWVRFAEELERRKITVQKLSWYKDGGSYVVPLRVTAEGKTIEATLRVNVIGGKLKEVTISGK,0.018462287127385252,4.615571781846313,False,False,False,0.6195029616355896,91.81086284819986,0.5,0.2403846153846154,0.81175 +82,F082,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,6D0T,VPDLKKVLPGKYSYTLEAAGPPVITGDATFKPVDDGVVRVTSEGTKSGGEPISGEYTITRADGGALEYRETLSDGYEFRGTPTFVSEDLIEITAENSEGLTVTGSLTRLPD,0.0400671570350624,10.0167892587656,False,False,False,1.0885957479476929,89.13234307107493,0.0022,0.25225225225225223,0.88272 +83,F083,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,6D0T,SLDLTKELQGRVSFTLTAPGPPTITGVANIRPVDGEKVLIEHKAVNSAGEPISGIGYIEKDGGSKPKVSLVFSDGQVLTGYYTFVSEDEILIKGRYSDGDIVEGTWTRLPD,0.07543364116939073,18.858410292347685,True,False,False,1.1696112155914309,89.83817957215413,5.7,,0.49535 +84,F084,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,6D0T,SLDLASDLKGEYSFYLENAAGRSITGYITVRPVDPSVVEIRTKAVNSDGVPVYGTGYVTRDGGSKPKVTLVLGPPLIIEGSLRKESEGEFRVKATLSAGEEVTGRFTKIPD,0.030757727520846254,7.689431880211563,False,False,False,0.856549084186554,91.328890772023,2.6,,0.9077 +85,F085,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,6D0T,RPPLEEAYVGWYRVTLTSREGLTITGLVTVTPVSPEVLNIEVTAVNSAGTPLKGIGYISEGPPGPPVFSLVLDGGYEFRGDITVVGEDEIRVSATSSDGLDVTGTFTKLPE,0.029582706827141456,7.395676706785364,False,False,False,0.8497048616409302,92.4071064287583,0.29,0.25225225225225223,0.376 +86,F086,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,6MRS,LDPAVFRVIEAIIRAVEGIGSPVYIFLSPDSVLIEITGLTEPEIARLTKVVAESAERYGVPTSLRIDGGTVSILVQA,0.04638047838827145,11.595119597067864,False,False,False,0.4881626069545746,95.27932442103456,15.0,,0.51141 +87,F087,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,6MRS,SPPKVNALIEAILEATRDSGFRVTIRESDGGSTIRITGLTPPDIARLLRVVAEASAELGVPSTVLVAGRTLIVTVSW,0.038991302018317235,9.747825504579309,False,False,False,0.9341968297958374,93.33669438860584,2.4,,0.70646 +88,F088,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,6MRS,FSEKTLKVIAEIVEAVKGLGSPLYLFVTPDKVTGYIAGLTPPEIERILEVVARASAEYGIETTTTVDGGSLRVTITD,0.08912437224937385,22.281093062343462,True,False,False,0.5166324973106384,94.78244900295392,0.34,0.3116883116883117,0.57541 +89,F089,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,6MRS,RDEGTYELINAILKAVEGSPARPRIYEGGGSAVIVITGLTPPEIERLDRVVKEAGRKTGVPFSLRVKDGTLTVTVSW,0.0237274715701571,5.931867892539275,False,False,False,0.7228794693946838,92.31426257702373,2.2,,0.55537 +90,F090,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,6MRS,SNAAAEYLLNVIREAVKGLPSPITERRDGGSTLVEIENLTPEDIARLKAVVKTAGEETGVPYRVFVGGPTVTILISW,0.018787930568922893,4.696982642230723,False,False,False,0.9679087996482848,94.93896683420776,5.1,,0.94399 +91,F091,Fixed_Rd2_compare_AF_ngram_20,AlphaFold+ngram,6D0T,SLNLKEDVVGKYRFLLVSEEGASIEGIATVKAVNPEVVEIEYTGRTSAGKPISGQGYISRDPPGQLKLTLLFDIGLVLEGTITKVSENEFRVNATSDGGSKITGYFVKVPD,0.19157571455457184,47.89392863864296,True,False,False,0.8795504570007324,94.01044187538032,5.9,,0.60468 +92,F092,Fixed_Rd2_Motif_11,LM,6D0T,MASLADVLAGTYTVTGKSPAGQEYKGEVVIEKVSDTKLKVKRTITTPDGKPVTDEGEATVSAENVVTFTAKNKDGVEISGKYTLEGKDKIKAELTAADGSKASEEWTKKTS,0.4294321330847011,107.35803327117527,True,True,False,2.5218183994293213,87.65193392239404,0.18,0.27927927927927926,0.83247 +93,F093,Fixed_Rd2_compare_LM_24,LM,6NUK,MPTVTLSAEIPVKDRETAEKIAKELEAKASEISSKTGGSVRVSTSVSGDTVKVTATITDAPPEVVKAVEEVLKPIVEKYGGKLTVSR,0.342255516940417,85.56387923510425,True,True,True,1.4239349365234375,86.81879193111219,0.33,0.27586206896551724,0.5938 +94,F094,Fixed_Rd2_Motif_11,LM,1QYS,MVKVTYTITKDGKTFKGEREVSDPSEIKPVVEKLIEDAKNAGATSVSVEVTAESKEKAEEVKKAVEEALKSAGLTNVTVTLEGTTLKVSGSL,0.4990069812474674,124.75174531186686,True,True,True,2.132812976837158,89.96011297143937,0.077,0.2608695652173913,0.49928 +95,F095,Fixed_Rd1_48,LM,6W3W,ADDKAAITDVVNKLIKAVNEKNAEALKELTAPGVEIVIEGQTVSKPEDLVKGLSEAKIDSATVGEVKVEGDKASVPATLKAGEETTPGTFELEKKDGKWLVTKVTLQ,0.4305501431758556,107.6375357939639,True,True,False,1.870003581047058,86.81428747758584,1e-05,0.308411214953271,0.85199 +96,F096,Fixed_Rd1_48,LM,6W3W,AGDEAAVRAVVKSLVDAENAKDTTKLKALLSSSATVEEDGKTVSGRDAVLAEIAKEKVTGYTLGEVTVKGSEASVPVTITADGKPEPATFTLKKEGGKWVISKIVEK,0.34157332772079496,85.39333193019874,True,False,False,1.675412893295288,89.52935934106502,8e-05,0.3644859813084112,0.78333 +97,F097,Fixed_Rd1_48,LM,6W3W,SPEEAAVKDVVNKFVELIKAGKYDEAKNLLSSSATIVVDGKTVTGRDAVLEKLKSEPPTSVEITKVSVSGDTATAEGTVTKDGEKKPVKVTLVKEGGSWKISKIEVQ,0.19536385993824054,48.84096498456014,True,True,False,1.7062160968780518,95.06005609985051,9.2e-05,0.34579439252336447,0.89644 +98,F098,Fixed_Rd1_48,LM,6W3W,MSAENKIKEVLEKLKSAAGSPSESDLSSVVASNVTLTIDGKTVSGKDELVKALKEAKVTDVKVDSVEEKNGEYTATGTVTKDGQSKPVKFTVKEEGGKYVITSIEVK,0.23774272150668382,59.43568037667096,True,True,True,2.2278475761413574,86.84431080836934,0.06,0.2803738317757009,0.8568 +99,F099,Fixed_Rd1_48,LM,6W3W,MSAEDKVKEVLTSLVNAAKEKKSSDVEKLLAENVTLEIEGKTVTGKDAVVKALSEAGVTDLKVDSVTEKDGEYTVSGTATKDGKPTPVSATVKDDGGSFKITKLTIK,0.23592128304088208,58.98032076022052,True,True,False,1.926544189453125,90.262273711329,0.15,0.19626168224299065,0.83195 +100,F100,Fixed_Rd1_48,LM,6W3W,MSAEAKVREVLDKVVAAVNKKDEAGLKALLAPGAKIVEDGQTVTGVDAVVKELKDSGITKLEVGEVKAEGGKYTVPATLTDGGSTSKVTFTVEEKDGKPVITEIKSE,0.4043727545699978,101.09318864249946,True,True,True,1.897280216217041,87.15427816645891,0.00077,0.3177570093457944,0.75264 +101,F101,Fixed_Rd1_48,LM,6W3W,AGDEAAVRAVVQSVIDAENAKDSAKLKPLLSSTVTLEEEGKKVTGLDAVLAEVAKEPVTKAEITDVKVSGDKASATVKETEDGKTETATFELVKEGGSWKISKIVEK,0.37507375671603954,93.76843917900989,True,False,False,2.0780415534973145,88.30627886885424,2.9e-06,0.3925233644859813,0.74489 +102,F102,Fixed_Rd1_48,LM,6W3W,MSDEAAVRDVVNKYVAALEKKDSATLKTLTASNVTIVEEGKKVTGLDAFVKEAEKEKPSKITVGEVSVSGDKATVPVTEVEDGKTTKSTFKLVKDGGKWLISEITEQ,0.27505544121764547,68.76386030441137,True,False,False,1.9738805294036863,87.71122586251461,1.3e-06,0.38317757009345793,0.80058 +103,F103,Fixed_Rd1_48,LM,6W3W,AGDEAAVKEVVNKLIEASKAKNAEGLKPLVAENVKIVSGGQTVTGRDALLKSLSDSGVTEYKVGEVKVEGDKATVPVTATKDGKTSTTTFTLEKKDGKWVITEIKSE,0.32059223185798696,80.14805796449674,True,True,False,1.9781895875930784,87.12275126881077,1.7e-06,0.3364485981308411,0.87358 +104,F104,Fixed_Rd1_48,LM,6WVS,MEYIVEVDTPERVSEIVKTLKESGASNIALVSSKPDLVIEAAKAGIEKVILTPGSLEDARETVKKLKEVGVKDIGLITSEPSLVLEGLRAGVGEYVVELDSAENAAEVVKRLKDGGAKNVAFVTTKPELAVEAVKAGVEKVVLSPATLEEAKETVRKLREAGAKDVAIISTEPPLILEALKS,0.3807309294882399,95.18273237205997,True,False,False,1.6833454370498655,83.07913801333038,0.036,0.3076923076923077,0.58145 +105,F105,Fixed_Rd1_48,LM,6WVS,MIISVRAENKDELTSTVKELKDKGIENILVVTKDLDSAVAASKGGSEYVVVEVSEPGKAGETVERLRKEGVKRVAVISSDPKVIEKALEEGTPIVSVKAKNKEELSSTIKKLKEKGVENVLAVTEDLESAITASEGGAEYIVVKVSKPEEAGKTVEKLREKDVKRIAVVSSDPEVIKKVLEK,0.06826551071176487,17.06637767794122,True,False,False,1.4189119338989258,85.69943641442232,0.044,0.18681318681318682,0.42681 +106,F106,Fixed_Rd1_48,LM,6WVS,MITVIEGKDPATIKDSVTKLRAENVSEIAFTSTKPGLIVEAAKAGVSLAVLDVKDGTAVNESVKKLKEEGVEKVAVVSDKPEYIVDAARAGASLTVVEGRDSATVKESVTRLKAENVGEISFVSSKPELIIEAAEAGVPLAILEVKDETTVRESIKTLKEKGVKRVALLSDRPDLVLEALKS,0.04873738323755056,12.18434580938764,False,False,False,1.4892292022705078,86.73085885026522,0.0056,0.2087912087912088,0.41517 +107,F107,Fixed_Rd1_48,LM,6WVS,MLPLIRVNSLDRAVEIVKEFRDKGVEYIGVVSSRPDVVEKALEAGTTLTIVEAENLEDAIKTVKELREKGAKYTGLVTSDPKVAEEGLKAGVTLVLIEADDLSTATETVERLRKEGAEYVGVISSKPEVVKKSLESGATLALVEAKDLDSAVKTVRELKDGGSKYVGIITSEPEILEKVLKL,0.08324956966583831,20.812392416459577,True,False,False,1.1505229473114014,89.9793096191984,0.099,0.2802197802197802,0.73144 +108,F108,Fixed_Rd1_48,LM,6WVS,MLPLIVSKDPSSVTETLRELKNAGVEKFGVVTSEPRVLIEAVRAGLDLAIVVAEDENSLTKTLEELRKEGVGKYGVLTDRPEVLVKAVKSGVDVAFVTARDGGSVSETVKKLKDAGASKIGVISDKPEILVEAAKAGIDLAVVIAKDGESLSATLKRLKEEGVERYGIITNEPKVLLEALKG,0.11101001510221765,27.752503775554413,True,False,False,1.3169331550598145,88.29019890735734,0.0047,0.25824175824175827,0.76291 +109,F109,Fixed_Rd1_48,LM,6WVS,MIPTLTSKDEGKILETVKRLKELGVPRVSVVTKNLDVAVRAGEVGAEIATVVADSEDELIENAKKLKDAGIERISFVTDKPETAVKAAEAGSEIVTITSSDPSKLVENVKALKEKGVSRVSAVTKDLDTAIKAGEAGADIATIVAESEEELLENVRKLREAGVERVSIVSDRPEVIEKVLSL,0.062017321415891655,15.504330353972914,True,False,False,1.0949746370315552,90.00291529801315,0.11,0.23626373626373626,0.75715 +110,F110,Fixed_Rd1_48,LM,6WVS,MKPVIISSSLEEAVKSVRVLKEKGVKDIVGISDSPEVASRLAEEGTEYVLVSAKDEREAGETIEKLKKAGVENVTGLTDKPETAVELSKRDVEKVVITSSTLEDAVNSIKILKENKVKNIVAISGSPEIASELAKEGAEYVVVSAENEKEARETVKELRKAGVENITGLTDDPKTALKLLEG,0.0769709084937476,19.2427271234369,True,False,False,1.5414249897003174,80.88010187607468,0.045,0.25274725274725274,0.43877 +111,F111,Fixed_Rd1_48,LM,6WVS,MKVLIEVSEPSKAVETIRKLKEAGVENIAVVTSKPDLAISSASEGAEYVVLEVKDGETATKTIKALRDSGLKRVGVLTDKPEVAKESAKAGAEYVILKVSDEDTAVKTVRELKDAGLSRVAVITNKPELAKKSAEGGAEFVVLDVKDEETAVNTVKELRAAGLERIGIVTDRPEIVEKLLKG,0.1740522297376026,43.51305743440065,True,True,False,1.2983237504959106,88.48472686298933,0.043,0.23076923076923078,0.85539 +112,F112,Fixed_Rd1_48,LM,6WVS,MRVLLTVEDEETGKRILEKLKERGVDKVGLITSSPDVALKASDAGTDLVIVTAKDGGSAAETIRKLKEKGIKEVSVVSSEPKVVVEASKAGANLAIVTVKDEDSGKKTLEELKKEGVNKIGLVTSTPEVAVKASEAGADLAVVTAENEESATKTVRELREKGVKEISIVSSKPEIIEKVLSL,0.18326693405062214,45.81673351265553,True,False,False,1.3447251319885254,86.39240099374861,0.015,0.2692307692307692,0.86934 +113,F113,Fixed_Rd1_48,LM,6WVS,MRLLIEASNEKEALDIVEKLKKEGIERISAVTDKPEVARKLADGGVGEVVVRAEDEGTAVNVIKELRDAGLTRVAAVTTKPDVAKRLAEAGASRVLVEAPDEETATKTVKDLKDSGLQRVSAITSKPEIAKNLAKAGVSEVIVKAENKEEAVKVVKELKSTGLEKISSVTSDPSVALEILKG,0.30177932691580905,75.44483172895227,True,False,False,1.3554872274398804,84.05546735970879,0.023,0.25824175824175827,0.71213 +114,F114,Fixed_Rd1_48,LM,6W3W,PAGEAAVKDVVTKLVDAVNKKDSAALEPLLADSVKIVEDGKTTTGKAEVLKELKDGGAKDLKVSKVEKSGSKYTVTGTATIEGETSPITFVVEEKGGKPVISEITEK,0.2547350336464487,63.68375841161218,True,True,True,1.8296480178833008,88.3476609536108,0.0055,0.35514018691588783,0.8636 +115,F115,Fixed_Rd1_48,LM,6W3W,MSDADAVKAVVEKVNAAAEKKDEAGLKELLAENVKITVAGKTIEGKDKVLEALKSAPPSKREVGEVSVKDGTATVPVTVTAGGSTTKLTYTLTKSGDKWLISEIKAQ,0.4039984347925847,100.99960869814618,True,True,False,2.014538526535034,88.72275449950267,0.0077,0.32710280373831774,0.81728 +116,F116,Fixed_Rd1_48,LM,6WVS,MRVLVSAKDENSAVETVRQLKNAGIEKVGAVTSKPSVALRLASEGLDYVIVEARDVNEAAEVVKKLKESGVSKVGSISSDPSTAVSLAKAGLEYVVVDAPDLETATKTVKELKDAGVEKIGAITSRPEVAVKLAKEGLSYVLVEVKDVEEGKKTIKELREAGVERIGTVTDKPEIALEILKG,0.20136769663932136,50.34192415983034,True,False,False,1.80736780166626,85.90858703824641,0.018,0.21428571428571427,0.89501 +117,F117,Fixed_Rd1_48,LM,6CZJ,MTVAEKLAGKYTGTAKDDKGNEVTITLEIKKESDTEYTVSSTSKTKDGKEVKASGKAVLKDATTADVTLTGEDGKPVVGTYKIEGENKVSVTFKSPEGVELKGDLTRVK,0.40187536250134254,100.46884062533563,True,True,True,1.0732301473617554,90.77154708387503,0.33,0.22018348623853212,0.87436 +118,F118,Fixed_Rd1_48,LM,6CZJ,MSVLDKVAGTYVVEGKTPDGKPISGELKIEKKGENAVKVSGKLTSPEGKEEPLEGEATVKSETEVSATLKTKDGQEIKVTIKFKDADTAEYTVTLSDGSTITGTAKRKK,0.3269384803644804,81.7346200911201,True,True,False,1.342326283454895,86.96862546869347,1.7,,0.8631 +119,F119,Fixed_Rd1_48,LM,1QYS,MVKVTVTGTKDGKPVTKTFEVSSLDELEKKVKEEVEKLKSEGVTSVTLTVEAPDASTASKAKEIAENALRKAGYTGLSISVSGNKITITATR,0.23823675466455083,59.55918866613771,True,True,False,1.480959415435791,92.34708158697816,0.73,0.21739130434782608,0.8881 +120,F120,Fixed_Rd1_48,LM,1QYS,MVKVTITFTKDGKPVTKTEEVSDPSKLEDVVKKAVEEAKSAGATSVTVEITADTPEKASEAENVARKVLESLGYTGLTVKREGNKITVTATL,0.29713331758258826,74.28332939564707,True,True,False,1.650942087173462,92.96180670085404,0.82,0.30434782608695654,0.86817 +121,F121,Fixed_Rd1_48,LM,1QYS,MPKVTITGTKDGKPVTKEIEVSSRAELESKIKEEVEKLKSEGVTSVTVEVTAPDEASKKEAENIARDVLTKAGAKNVQVSVEGSTVKVSATF,0.283977524363175,70.99438109079375,True,True,True,1.661885142326355,90.57610364778702,0.79,0.2717391304347826,0.51044 +122,F122,Fixed_Rd1_48,LM,1QYS,MPKITITGTKDGKPVTKEVEVSDPSKLEEAVRAELEKLKSEGVTSATVTVKAPDESTASKVKEIVEKVLKELGAKDVSVSGSGGEYTIKATF,0.4962038371617647,124.05095929044117,True,True,True,1.7360239028930664,89.62163197601475,0.085,0.2391304347826087,0.59121 +123,F123,Fixed_Rd1_48,LM,1QYS,MVTVKITGTKDGKPVEKTLEVSKPSEIPGAISKLTEELKSAGVTSVTIEVTASSKEDAENAARVAEAVLKGLGYTDVSVKVEGNKATITAKK,0.2742051074536023,68.55127686340059,True,True,True,1.7395225763320925,89.79718220084987,1.5,,0.46493 +124,F124,Fixed_Rd1_48,LM,1QYS,MVEITVTGTKDGKPVTKTFTVEKPEDVPKVIEKVLEELKKEGVSEVKVTVKASSKDEAENVARVVEATLKAAGAKEVSVSGSGGEYTITAKL,0.35067152355882203,87.6678808897055,True,True,False,1.992031574249268,91.4011528958854,0.72,0.2608695652173913,0.79074 +125,F125,Fixed_Rd1_48,LM,1QYS,MVEIKITGTKDGKPVTETLTVSSPSDIDSAVNKVLEKLKSEGVTSATVTVKASSKEEAENVAKEVEKRLKDAGFKDVKVSGSGGEYTITATR,0.454025108550495,113.50627713762375,True,True,True,1.5798276662826538,89.53139849225488,3.0,,0.54812 +126,F126,Fixed_Rd1_48,LM,1QYS,MPKITITGTKDGKPVTETVEVSSVDEAVKKLEEKIKELKDAGVTSVTLTIEAPDESTAKDLASKAENALKSAGFKDVKVSVEGNKVTVTATL,0.3255327815620091,81.38319539050228,True,True,True,1.53373122215271,89.86168090861035,0.11,0.2608695652173913,0.85828 +127,F127,Fixed_Rd1_48,LM,1QYS,MVKLTITGTKDGKPVTKTVEVSSPEDAVNKVKEILEELKKEGVTSATVVIEAPDEKTAENAKRVAEALLKAAGAKDVKVSVEGSKITVTATL,0.47971685757209886,119.92921439302472,True,True,True,1.7418758869171145,88.89922296487072,1.5,,0.83836 +128,F128,Fixed_Rd2_Motif_11,LM,6CZJ,MTVLDKLAGEYEVSGKDAAGNEYKGTVKIEKEGENKAKVTRVITGADGKPVTSSGTATLESDTKLSVELTTEDGQKVSAVETIKSDDEREIVVTLPDGSKLTETWKRKK,0.42573097655642544,106.43274413910636,True,True,False,1.3811442852020264,89.96638561423804,0.061,0.22935779816513763,0.85718 +129,F129,Fixed_Rd1_48,LM,6CZJ,MTVLEKLAGKYTITGKTPEGEEISGTVEYKKEGDDKVSVTRVIKTKDGKEVKQTGTATLKSDTELSIELTAEDGSKVTGVETLVSENERKVVLTTADGQKIEAVEKRAS,0.1969993130688227,49.24982826720568,True,True,True,1.1307755708694458,92.23752939601708,0.16,0.21100917431192662,0.87003 +130,F130,Fixed_Rd1_48,LM,6CZJ,MSLAEKLAGKYTVSGKTPEGQEISGEYEFTKAGENEYKVVAKITGPDGKPVELSGTATLKSDTEAVVTAKDPSGREVTVTLTVKDADTIEGVGKAPDGSEIKVTGKRVK,0.400563139199727,100.14078479993175,True,True,True,1.1647963523864746,88.77604506515777,0.019,0.30275229357798167,0.89158 +131,F131,Fixed_Rd1_48,LM,6CZJ,MTVLDKLAGKYTIEGKTPEGEPISGTTEVTKKSDSEVALKSVIKTKDGKEITLEGVGKPVSDTSVKVELKAADGSTATAEYTFKGDDAVDVKVTLSDGTVITGTEKRAK,0.305597507227619,76.39937680690475,True,True,True,1.219199776649475,87.58026920980092,0.91,0.23853211009174313,0.80478 +132,F132,Fixed_Rd1_48,LM,6CZJ,MSVLDKLAGTYEGTAKSPEGKELKVTVTITKDGENKAKVVIEAPGPDGKPIKAEGEATLESDTSASFKVKTEDGQEVTGTVKLVSENEIDVEYTLSDGSKISGKLTRKK,0.4585908282289566,114.64770705723915,True,True,False,1.7507332563400269,88.66633659573229,0.047,0.27522935779816515,0.74559 +133,F133,Fixed_Rd1_48,LM,6CZJ,MSLADKIAGEYTVTGQTPDGKPISGKLTITKEGENKYSVKGTLKDPEGKEEPVEGTATLESETSAKVSLKTKDGKELSGTVEVVSDTEIKVTLTDAEGNKIEVTAKKAS,0.386734824659598,96.6837061648995,True,True,False,1.0890276432037354,87.8132647979346,0.19,0.26605504587155965,0.94502 +134,F134,Fixed_Rd1_48,LM,6CZJ,MSVLDKLAGKYEISGKDAAGNPVTGTSEVTKVSDTKASIKSTVTTADGKTIELSGEATEVKPGVVSAELTTPEGKKAKVEITVKDENTRDVVITLEDGSKITAVEKRVK,0.29136398284163545,72.84099571040886,True,True,True,1.4823777675628662,87.96171146295072,1.3,,0.88796 +135,F135,Fixed_Rd1_48,LM,6CZJ,MSVLDKIAGTYEGEAKDKEGKPVKAKLVITKDGGSKVNVELTVTTPDGKEKKLSGTGEPVSETSVKVTLKDEEGNEVTATIEFKDADTAVVSGKTPEGVEIKGTVKRVK,0.356295626261776,89.073906565444,True,True,True,1.7677292823791504,86.80593495491695,1.8,,0.83906 +136,F136,Fixed_Rd1_48,LM,6CZJ,MSPLDAFVGEYTGTLKTKDGKEVPVTVKIEKAGENEVKVSVSGKTPEGKEIKASGTAKLESETSAKVTLTLEDGSTVEATITKPSDDKLTVTGKNAEGQEISGELTRKK,0.43271550606435516,108.17887651608879,True,True,False,1.358462929725647,89.08745904116874,0.3,0.21100917431192662,0.68446 +137,F137,Fixed_Rd1_48,LM,6CZJ,MSVLDKLAGEYDVELKSADGKPIKGSLKIEKTSETEGKVTGTITTPDGKEEPVEGTVKASSDTEATVTAKTKDGQEVTLTVKVVDENKLEVSGKDAEGNEISGTATRKK,0.4135837874338196,103.3959468584549,True,True,True,1.2818390130996704,89.9499049610178,0.49,0.29357798165137616,0.69754 +138,F138,Fixed_Rd1_48,LM,1QYS,MVKVTVTYKVGDKEISETKEVSKPEDVPKIVEELVKKLKEKGVSSVTLTIEAPDKTSAENAARVAKAVLEGLGAKNVEVKVEGNKATITATF,0.1913173988144506,47.82934970361265,True,True,False,1.7961807250976562,91.92466852220964,1.3,,0.83248 +139,G139,Generation_Rd2_Distant_57,LM,N/A,MKAGAEEIKTSATSLKDSVSSGTVDPIVTEAGKVLDAAKAVKEKVSEADKPKVEPVVTKLETAATDLKTKGEAKDVTGLTTAVNEVITASDELVKLLPAS,0.20507356097996407,51.26839024499102,True,False,False,,90.45868949690686,0.076,0.28,0.39181 +140,G140,Generation_Rd2_Distant_57,LM,N/A,MAADVPPEVKAGLDSVNKAVEVSGSDATVEQVTGPLKEALEKYKVAAEKVTKPDGKTKLEGVIKDIEGAITAGEAKDLPKVKELAGKAKTSSEEIVKLLS,0.3328677079393693,83.21692698484233,True,True,True,,84.99285539872803,0.22,0.32,0.83491 +141,G141,Generation_Rd2_Distant_57,LM,N/A,MSPAARAELTETRNDVTKLIKTVKDGGSKSTIAKEASEISGDLDKAITLTAGKPKAVAELRETSADLKKLVATVKAGGSKSVIVKEAGEVSSDIDKVLAL,0.1551972832114287,38.799320802857174,True,False,False,,93.5872682057466,3.8,,0.49823 +142,G142,Generation_Rd2_Distant_57,LM,N/A,MSEIETVITGLTTARDSVVAGSKDGGKSLVEVGKTLVELAKAEGVSDDVKASIKDAGKPIVEAGKLLKEGEPPEDKVTEAVTKIDEAITALNAALESAQG,0.2756433114334177,68.91082785835442,True,False,False,,86.87348946971616,0.82,0.31,0.48043 +143,G143,Generation_Rd2_Distant_57,LM,N/A,MARVISKTITVSATGESDPIEVPEDEGKYIVAVNVTSLSGSPSVTVEILKDGDSTPEYTLTASAGETKSEPVKIKAKKLKVKVTAAGGSSGTATVTLVLE,0.027529949935088758,6.88248748377219,False,False,False,,83.71902057521575,0.5,0.23,0.48523 +144,G144,Generation_Rd2_Distant_57,LM,N/A,MVSEEDIKKAVENKAKEKLQEELSKYGVSATLTVTDVKVTEPPKITKDGKVIVVAEGSGTATIEAGPLKGKTASFRVRAEVDPSTGEVKSVEILEVTVSS,0.38875352995405293,97.18838248851323,True,True,True,,88.74604251379841,9.5,,0.44431 +145,G145,Generation_Rd2_Distant_57,LM,N/A,MATKDDVTKLVSSVTGLLDKVGSASTVPEIQAVAKELEGTIEPLEKKAKDGGAESEVEAVEKPAEALEDAAKAGSDKSAIDTAVTNLKTSLTTLAGKLSG,0.222212473773112,55.553118443278,True,False,False,,88.46027073589488,0.18,0.29,0.3727 +146,G146,Generation_Rd2_Distant_57,LM,N/A,MTVEEIKKASDTLVSSGTELKTAADAGNLDKVKELSATIVTSGETLQKGLEGKPEVLEAVNAVVTAGKDLKAAAEAKDVEKIKALTPVIVEAGTKLKSLL,0.41143414845372267,102.85853711343067,True,True,True,,90.46682388380894,0.75,0.19,0.78525 +147,G147,Generation_Rd2_Distant_57,LM,N/A,MNAALEKAKTATDVPSAVTAVKEAITVAGSKPEDAEPVVKAGVELVKVLKDGGSLDAAENVAKEVTTISGTPGVSDSVKTSASEGLTEITKLIEEKKSGK,0.091279198227127,22.81979955678175,True,False,False,,86.53972629608363,3.3,,0.60999 +148,G148,Generation_Rd2_Distant_57,LM,N/A,MSSLSDIKSTVASITDVSELEPVVEPLTEIIEGGGSDADKVEAVNVIGEVGKKLGEAGEYDVLESVLPPLEELAEDSSVSAEVKEAATKASETISAVTAE,0.18933746095612405,47.334365239031015,True,False,False,,88.14748754664437,1.5,,0.50912 +149,G149,Generation_Rd2_Distant_57,LM,N/A,MKALENAADEIKKSDSRITDVTASVSGTTVSARVTLAEGVTEDQAKPVLEEVVPKISEAATKGLKDAGEPSTLTIVAVSSKDGKELVRATSLGGSVKVEK,0.3332914704062595,83.32286760156488,True,False,False,,88.37161919753758,0.79,0.18,0.41947 +150,G150,Generation_Rd2_Distant_57,LM,N/A,MKITLTVPPGKTVKSDPIKAAGRVSASVKVTAKDSSKPAKVRVLAVPEGGSEPVTVVEKEVKAGETATLEPLDTTGYTEYIVEAENVGDEEATVTIELSG,0.336444292189329,84.11107304733224,True,True,True,,87.98001209003614,1.6,,0.53459 +151,G151,Generation_Rd2_Distant_57,LM,N/A,MAELDTIKSGLTDLKTKVDGVVADPSSVTPETVTGLSDSAKTLGESLEGSPVQEVKDAGKELSEASKAAGEETEPAKIVEKLTTVSTAVGKVITAAENAA,0.26587976795727936,66.46994198931984,True,False,False,,89.96433851537665,1.6,,0.41494 +152,G152,Generation_Rd2_Distant_57,LM,N/A,MATVKEVLTEISTKVTAAGEAKDVPTLTTLSGEITGLIEKLKPLVEGKPELTPVVDGLTAVSEASKKVGEDGSAENVAAFTKAVTDLKTSLDAGIKALEG,0.4991924215797286,124.79810539493215,True,False,False,,87.48442474556842,1.5,,0.47016 +153,G153,Generation_Rd2_Distant_57,LM,N/A,MPKYTVTLTVKLSGKPEPSKISEIENAAKSAAESVAGEGVSVKVTKVEVKDDGTATITLEVTASGSEDEAKKKAEELKNKIKEAVEKAGGSVVDVTVSTS,0.42333046694985677,105.83261673746419,True,True,True,,88.78546222717601,0.14,0.26,0.46378 +154,G154,Generation_Rd2_Distant_57,LM,N/A,MTEKITADVTKALEEAGVTPGKVEVSGSTVKVTLTVPEGTDEATAKTTAENAVNAAVKGLKDAGESVSSVRVIVVGKDGKELASATSLGGSITIKPAPSE,0.4531835261231916,113.29588153079791,True,False,False,,87.75473846202736,0.1,0.27,0.55879 +155,G155,Generation_Rd2_Distant_57,LM,N/A,MSDVKITKNEDGTVTATGTAVLTPEDIKAAGGSEEKAKELAEKRAKDSARESLRLLVKAENPDLKDEEIDKLIENIKVVSSKPVEGGVEVTVEASVKVGK,0.37388402065682946,93.47100516420737,True,False,False,,88.89236488239041,0.43,0.23,0.54614 +156,G156,Generation_Rd2_Distant_57,LM,N/A,MSDISATVTGLSESVTALGTAVSSGDVEGVKTAGEDLKAKLKELETSAEEAGAKDLVKEIKDAGKAVVKVGKDGGSPEEVTPPLTTLQEKLTELSTKLAG,0.33130961826060645,82.82740456515161,True,False,False,,87.8328885327107,0.068,0.31,0.87952 +157,G157,Generation_Rd2_Distant_57,LM,N/A,MKDVSDKAEAELKKIDGVEDASVSLQVTPPSFSGSITVKEGTDEATAKEIAKNAGKVAARVLEEEKLTEYTLTISVTGEPADGGSSKPVGSATFTKDDLK,0.3887420302984773,97.18550757461932,True,False,False,,85.66335758481124,3.3,,0.48156 +158,G158,Generation_Rd2_Distant_57,LM,N/A,MSEISTAATEVETAVNKLVSDIEGGSEPSFDSVSADLTKAGENLEKASAEAGSDEKVTSAVTTIKEGITLAKDGVSGKDVAKVKEGAEKIKTGLDGLKAL,0.24084138782798684,60.21034695699671,True,True,True,,88.22556618126865,0.58,0.2,0.46527 +159,G159,Generation_Rd2_Distant_57,LM,N/A,MPKITVENKSGVDATITLEAGSFKDSKTVAKDGGTAEFEVKEKPSEPLEIKAKADVPGKGSAESDPVKVELKEGETAKVTVTLTVGEDGKLSVSSTTTKE,0.2227111388280504,55.677784707012606,True,True,False,,84.9238082614045,0.67,0.33,0.49835 +160,G160,Generation_Rd2_Distant_57,LM,N/A,MEFRIKTSKPPEEVLKAVKEALSSDPKYKDVQIVSESPSEIVAKGRAGTATVRVSVKDGEVTISGSAEGGLITKSLVEKKLRELAENAARKVPGAEVVTG,0.24038289936562846,60.09572484140711,True,True,False,,88.59548342136148,1.5,,0.48746 +161,G161,Generation_Rd2_Distant_57,LM,N/A,MSDEVKSVVADLKAAVTSLKDAGSSAENLKPVGEKLKEIGTKLSGLTVPEDKKAKVTELAGKIKDGGEALVKAGESGKPDDVKTAITTIETAVSELEGLL,0.42792015185193416,106.98003796298354,True,True,True,,89.05788763849755,1.2,,0.7236 +162,G162,Generation_Rd1_48,LM,N/A,MSSEEITKATEDLTTAKDSGDTDKIVSAVETLVSVTGSPSDVPPEVQLASIEALGYVVENAEGGVADKVKEAGAKERLEELKDAGEPVGEAAGKVLEKLS,0.21005651574537504,52.51412893634376,True,False,False,,85.10657686493096,2.4,,0.43952 +163,G163,Generation_Rd1_48,LM,N/A,MAEVEISVEKKGENEYVVSVKVSGKPGTPPSEPVTATSLDDAVNKAKEKIKEALEKAGVTELKDSDTITIKVTVKEGEEGGSKTVTKTLTVGELRKLLEG,0.1357011772016441,33.925294300411025,True,True,False,,85.69054945839417,0.77,0.18,0.42333 +164,G164,Generation_Rd1_48,LM,N/A,MKTTVTLTADKPSEPVAVNAAENKASKITVKVTKAPEGGSATLKVVGKKDGKDVTVLEAKEVKAGESVTSDPIEGLTEYTVSLSGVPAGSTAEAEITVEK,0.364473906674991,91.11847666874776,True,True,False,,86.88541224847904,1.2,,0.52102 +165,G165,Generation_Rd1_48,LM,N/A,MSELENKIKEALSSIEGVEVKVGEPKVEEKDGKKVVTSVPVTITKDGKTYTLTVSKPEGSDKFRATVTAPDGTVVASAEGDTPEDAVNKAVEKLKEILGG,0.323444357381488,80.86108934537201,True,True,True,,86.51952648831619,0.52,0.23,0.54128 +166,G166,Generation_Rd1_48,LM,N/A,MATAKDVKAVVEKVEKGEPVTAEDLKPLIEGTKDSSFTVRVNSITGIGKLVEAGKVTPEVAKEALPVLEELRKDKTSVSGGQTVGGAAGSAISKIKKASK,0.07451008573836172,18.62752143459043,True,False,False,,83.85604869710298,1.2,,0.50281 +167,G167,Generation_Rd1_48,LM,N/A,MAGKLTVKVTGLSASDVAKVRVTATVTPSGGSPVELKPEEKEIKAGETSVTFEVSDIKEGDKVSVKAEALKADGTVEYTGSKDNVVPGTNEVTITLEKKS,0.2552751535613065,63.81878839032662,True,True,True,,85.82734665883672,0.21,0.22,0.76777 +168,G168,Generation_Rd1_48,LM,N/A,MSAKEVAEAFVKAVNAKDAAGVEKLSDGGSLTAENVQKVLDLIEKAGEYTVTDVGEPEKRETSSGTITVVPVTLKGSKDGKPLEFRVSVKDDKVTGLYIK,0.22973311193269697,57.43327798317424,True,True,True,,83.80963016732258,0.12,0.35,0.76997 +169,G169,Generation_Rd2_Distant_57,LM,N/A,MSVQEEITAKTTEISEALSSGDADKVVTGLTDLVTLIEKAGEPPGPVLENAATVLGTIAENKDVVKGKPEVVEKLKELAGKVEGGSDEVKEAVGRVSASL,0.3692888793736263,92.32221984340657,True,False,False,,83.33180243087995,1.7,,0.48083 +170,G170,Generation_Rd1_48,LM,N/A,MSPEDQKKLEELKPKIEKAAKDSASSSGADVKAEVKVEGKTAVVTLTVTVPDGGSKDDAKSTAENVAGSAVSEIKKEAPEITSVRVQVKSGDTTLVDKTS,0.07272598231771801,18.1814955794295,True,False,False,,86.38503262080307,0.62,0.2,0.54976 +171,G171,Generation_Rd1_48,LM,N/A,GKLEFTVKFSEPVDPSTIKAENIVVKVGDKEITLKPEDVTKVSDDGKEYKVTVTLTEEQLKAIKEAGGKVSVSIPEGAVKDAAGNENKASEIKDNTVEVK,0.353917321190868,88.479330297717,True,False,False,,88.99491429469761,0.11,0.3,0.64077 +172,G172,Generation_Rd1_48,LM,N/A,MAEYTATLTTSLPPSKVLEVTKSTLESEGLTITSSSDKEIKASGKGVSATVKVEAKDGGSVVTVTAKAGGLIGKKRAEELLNKIVEKLKSAPEVKDVKTS,0.08443556471481162,21.108891178702905,True,True,False,,85.9582238766821,0.16,0.2,0.69889 +173,G173,Generation_Rd1_48,LM,N/A,MSVSEEVTKASDAVNAAVTATDGSKSADEISTAVGEAKTTLEGLKDKVTGDAKTLVEEAITSLGEVETKVKDGGSPEDIKAALTPVAEKLKEAAGKLPSS,0.35514819735560493,88.78704933890123,True,True,True,,90.5134869098054,0.34,0.25,0.63993 +174,G174,Generation_Rd1_48,LM,N/A,KVTLDKAEIDPKDGSAKITGKVENVKEGEVSVVIKDSEGKEVAKGTATVKDGKIETTIEGLKLEKAGKYTVEASFKPTEGQEPVTSEKKELTVPVKVTLD,0.49288849535230767,123.22212383807691,True,False,False,,85.49357017737616,0.014,0.41,0.54795 +175,G175,Generation_Rd1_48,LM,N/A,MSDEVKAKIEEAIKSSGLPVTDVKVEGTTATVTVSDPSLVPAVLTIVAGAVKGVEGVSEITVKVVGSDGKELASATLKDGEYTVNGQKVTKPEDLEKLLK,0.43620360927076324,109.05090231769081,True,True,True,,87.11474597462664,0.99,0.18,0.5706 +176,G176,Generation_Rd2_Distant_57,LM,N/A,MKASEILAKLSGTYKDDEAGLTVEIKDGKVTVSAEGESAVLENVTSVDEKAGTATVKGKDEEGADVTLKITFSDAKNPSKVSVVEVTEDGETSEPVELTK,0.3844477984588167,96.11194961470417,True,False,False,,86.20851780777167,0.034,0.2,0.66728 +177,G177,Generation_Rd2_Distant_57,LM,N/A,MAVNKEETSEPITVPEGKKVKSVSGVATNKAGDGGSATLTVTIEGAGEPVTKTVELKDADTPFEVTGLDVPAGSTVKVTAKLSSDKPGTAEIKDLRVVLE,0.2654726003622822,66.36815009057055,True,False,False,,86.41534731482963,1.2,,0.58678 +178,G178,Generation_Rd2_Distant_57,LM,N/A,MATVQEIKDAVNAVLDSVEKKDLEGAKTSAETLKTKAEELAGSSDIPADVKEKVTTAATDAGTAAENLVTAVEGGSGDVSEPVTKLKEALTGLLSVIEGK,0.425398676935431,106.34966923385775,True,False,False,,87.68901877999998,1.3,,0.64483 +179,G179,Generation_Rd1_48,LM,N/A,MSEELRKAVENAAKEAAEKRVKEYLEKNPDLKDVTISDVKVVSVEEVPGEPPKKYKVTLTVSGTKDGKPVTATVTDIVEITEGGSPPTVKLLESKIETSS,0.29900936277246376,74.75234069311594,True,True,False,,86.02743373232883,1.3,,0.57502 +180,G180,Generation_Rd1_48,LM,N/A,MKDGEIKEVVKVLVEKLREGAENGSVTTISNAATGLGKVAERLEDDEIRDTVKEAVRVLIEKLKEGVENSSVSTITNTATSLSKVAGRLKDSEIKDAVKE,0.3213427087290815,80.33567718227037,True,False,False,,86.20820028410907,0.23,0.23,0.66443 +181,G181,Generation_Rd2_Distant_57,LM,N/A,MPKYRVVATVSVSAGSKEEAEKKASELVEKIKAKLEEKGLKDVKVTGTSLTEVSGGYTLTVTITAESDKPPSEIENAVREALKEAGVGEPVISSVTKVEG,0.25384446588434895,63.46111647108724,True,True,True,,88.54541706281088,2.7,,0.50116 +182,G182,Generation_Rd2_Distant_57,LM,N/A,MATLQEGVTTITGLVERLGSATSFDEVKTVAGEISDALKPIVEKAKESGEPSEEIKGPVTDLENAVKELKDGAEAEDSSKVTAAVGTVSTKLTELAGKLS,0.3724929920808958,93.12324802022395,True,True,False,,87.92727221288574,0.045,0.28,0.59423 +183,G183,Generation_Rd1_48,LM,N/A,MKVTRAENALRVVSSAVGQYTLEKGEPPKSLDDLVKAGYLKEDEAKELIEEVKVEGADAGTATITGKVKEGDKPVTVTLTVAKDGGSVTKTTTVDGKPAS,0.3468407943058762,86.71019857646905,True,False,False,,85.3267939260983,0.00012,0.26,0.54095 +184,G184,Generation_Rd1_48,LM,N/A,MAEITSGSKTVSGSETKLTVKAGETATVTLSADVTEIVVEKDATLTIEAAEGVKVGDKPITVEAGGKLVNNGTVTGNVTVKDGGSLEGKEVKGEAKIEKK,0.023438156178967277,5.859539044741819,False,False,False,,86.76730231087329,0.47,0.25,0.7231 +185,G185,Generation_Rd1_48,LM,N/A,MPVKVTITAPPGTKPSDVKAKIESEVIPKVLEEVGKPELAEKLKSATLTVTENPDGSVTAVLDVSGLSKEEAEKVAEITRKKLVEAGVPEDAIKVEVVEG,0.20753040061384626,51.88260015346157,True,True,True,,87.18989491808568,0.35,0.34,0.57824 +186,G186,Generation_Rd1_48,LM,N/A,MLVEITTSSGTKLVNAENVVSVTENSDGSATISFVGGSTLTVTGETVADVKAKLKPVIEGKIKEAEDKVAQLEKDGGAGSPEVTAAKAELERLKAVLASL,0.4051587468926507,101.28968672316267,True,False,False,,91.88900529299924,0.36,0.24,0.53372 +187,G187,Generation_Rd1_48,LM,N/A,MDLSEIKALVAAGKYEWDEGNVEKIAKHGVSPEEVEQVLENKPLIEPVPSKVKGETRFRVTGLTDGGRLLTVVFTVRGDDVIRIISARDATKKERKEYEG,0.16448825393008118,41.122063482520296,True,False,False,,86.01142421786548,9e-20,0.51,0.845 +188,G188,Generation_Rd1_48,LM,N/A,MSDSAVKEGKELLEKAKSTSDPLDKVSLLTDAATKLKDGGAPESEIKPVLVEAGKTGLSIVEKGGSSVPPSEKREILEDVAENLETAGEPDLAKEVRSKI,0.28479652189612137,71.19913047403034,True,False,False,,87.2741586468708,0.89,0.36,0.51479 +189,G189,Generation_Rd1_48,LM,N/A,MATFTKTVTLEAGKPSEPITGLSGRVKKITASISGGSAENVSAKLVVEKEDGTTETIELKAGESSVTKDLDPPVDVKSVKVEVTGAKEGEKATLTVTVEE,0.13369887066922734,33.42471766730684,True,True,False,,87.77665895300834,1.4,,0.49889 +190,G190,Generation_Rd1_48,LM,N/A,MKLVLTSSADVEYTISVNGGEPVTGTLKAGETKEIEVPAPEEGKPITVTVKVTAKNVKDGGSVSAKLIKVDKDGKETVVAEDSKSGSEATVELSKTFTVQ,0.14553392066270446,36.38348016567611,True,True,False,,85.23398740416752,0.49,0.22,0.55118 +191,G191,Generation_Rd1_48,LM,N/A,MARFRVTLTVTVKDADPSKVEEAKNAVKEALSSIEGVKVLDVRAGPVGGSYTITAIVEVPEGQEDKAKELAEKAKSEAENKLKEKGLEVTSVSASATPLG,0.07282996354878321,18.207490887195803,True,True,False,,87.53061091129207,0.91,0.2,0.60413 +192,G192,Generation_Rd1_48,LM,N/A,MSEITSLTTATLSSPSKTPVIVTASGSDITVRVLKDGKLEEAGKYSTGLVGKINSVSAKETGKDSFTVVAAGDGGAVELKVTVKEGEDGKPEVEKAEVVK,0.26659004459356195,66.64751114839049,True,False,False,,89.59009024552489,0.25,0.29,0.40602 +193,G193,Generation_Rd2_Manual_24,LM,N/A,MAVSSDVTVKAGKTLTLEKDSEVTGTITVEDGGSLILEEGAKVTATSITVKSGGSVTLKKDAELTAPSADIVVEAGGKLVLESGSKVSGKITNAGEIIKE,0.22727875498455913,56.81968874613978,True,True,True,,92.68699567297864,0.00042,0.31,0.8495 +194,G194,Generation_Rd2_Manual_24,LM,N/A,MAEFRVTGTATIDGESVPVVATVSDSEVSLAPEDGGDLPEITVPLSSISGLEKDGSTVTLTVLDEEGEPTEYTVELESADDAGEFVKAVRKALVEAKNAA,0.13058535749075587,32.64633937268896,True,False,False,,89.80239142712125,1.4,,0.72477 +195,G195,Generation_Rd2_Manual_24,LM,N/A,MKSLEGKKVLIVGGLDRLRPEYEKKLKELGAEVTSFSGRESRKTVEKITKEIKDGKYDLVIVLTNYVSHKVTTAVNKAAKEAGVPVVKGSPKRILEEISK,0.2438046900032924,60.951172500823105,True,False,False,,84.283443401976,3.6e-07,0.37,0.73891 +196,G196,Generation_Rd2_Manual_24,LM,N/A,MADISGKYEGKVSGEEEGDAVLDLKQDGSKVTGTITVPSENIKADVKGSVDGDKLTLEIEVPEAGETAKAELTVKDGKLSGTVTAEGESAPVELEKKTSS,0.03521260291153069,8.803150727882672,False,False,False,,88.46053178719052,1.8e-07,0.39,0.88997 +197,G197,Generation_Rd2_Manual_24,LM,N/A,MTKEELAAKLKGKTFVGEAEGVKVTLEFKDDGTAVITVDVPGQEPETGTYEVSEDGSTVTVKAGDEVVATGKVNDAGEIELTVEVEGEPVTIKLTEKPAS,0.31272403972533674,78.18100993133419,True,False,False,,90.26839772316754,0.01,0.28,0.70725 +198,G198,Generation_Rd2_Manual_24,LM,N/A,MATLEEVIAKAESDGKVSLAGEGLTDADVPKVVELLKSGKITSLDLSENKLTEASVDAIVAAVKEGGSKVTEVNLKGNEIKDSAPIEKLKAAGVTVTGVE,0.33709740965070456,84.27435241267614,True,False,False,,86.36919238098604,0.00021,0.35,0.85039 +199,G199,Generation_Rd1_48,LM,N/A,MAEYTSEPISLEGKKIKAVKVTLKEAPSSGTVTVELLDENDNVLATFTGLSVSAGETKTLTPPSPPTIPAGTKKVKVRVTASGSDGGAKDVVVEVIVEEE,0.10049578289951612,25.12394572487903,True,True,False,,86.52507613680642,0.39,0.29,0.64192 +200,G200,Generation_Rd1_48,LM,N/A,MSPEEILKELESKVSSGEISADEALSLAEKAVEGGSVDVLVKAAEVSAKAGKPEVTVKIVEKLIEKGVKDKRVIEAAINAARDAGDTETASKLEELLKTL,0.40972010352290444,102.4300258807261,True,True,True,,88.52770732744686,0.077,0.35,0.61949 +201,G201,Generation_Rd1_48,LM,N/A,MSEEVNKIKELVEKASGQYKDGKFDEGKTTLGEASTAVTGLEEKVKAAGGSAEITGPVTELKTSIETATKDVEAKSADAGTKLEDVSKKLTDLAGKLPAA,0.30720398423712897,76.80099605928224,True,False,False,,90.41036662944973,0.13,0.27,0.65927 +202,G202,Generation_Rd1_48,LM,N/A,MKLKDGAKLVIPPEIVEKIKEKHGVSEGEVLEALKNAAENSVTIEPSKTKPGRFRVTGLSGSRILTVVVEELDDGTVKVITARDASKKERREYEKAVGKK,0.0940098747249764,23.5024686812441,True,False,False,,82.49738499306618,4.1e-08,0.36,0.79272 +203,G203,Generation_Rd1_48,LM,N/A,MTIVRVFDSREKAENAVNELKSAGISSDAINLVSGEEGAKKLTEAGVPEDEARVYAEGVKRGGTVVTADVPDDKVSEVESILEKYGGSKPEPPSETPPAS,0.17221999174676836,43.05499793669209,True,False,False,,84.4356925716466,1.7e-09,0.37,0.81654 +204,G204,Generation_Rd1_48,LM,N/A,MEITISGKDLSAENAAKLKEAVTTAVNDGGSVKVTLTVSVPEGESDPKAAGQKLADALEAELKTVAGDKASSITKGEPVVDTSKPAGTPGVTATVEVTKS,0.12751274187278755,31.878185468196886,True,False,False,,87.70044338976987,1.0,,0.43692 +205,G205,Generation_Rd1_48,LM,N/A,MTPEEALERIRAAVAAGRVTVTKHVEKRLKERGLTTRDAVVSAVLAKAGTAELIEDDGGSKKYKVTGEVPGKDGKPVKLVVIVSLSDPSEPPRVITAYPA,0.20831051512177579,52.077628780443945,True,True,False,,84.10098394565233,0.071,0.32,0.77711 +206,G206,Generation_Rd1_48,LM,N/A,MTLTTATVDDAGKVTEISVTGLPGGSDPKAAGEKTAENVAALLEAVGAPEDGRKEVLDKLKEGSASLSEPVKVTKDGVEYTVTSSTVSGTPSFTITAKPA,0.32079452603050557,80.19863150762639,True,False,False,,84.62503673562736,1.4,,0.59321 +207,G207,Generation_Rd1_48,LM,N/A,MTIKSATLTATVTPPADAPEGSEITVSAQLVPVGEDGKPGDPIATSDSVTVKAGEEPKEVTLKLEGKDVDVTKGRVAVVITASGTEPVEVKVSNVKLTVE,0.32624960566135874,81.56240141533969,True,False,False,,87.13537223500181,1.2,,0.482 +208,G208,Generation_Rd1_48,LM,N/A,MLTEEQKTAIENAAKEAAEAKIKEELEKAGYTVSNVAVNKDSIVVKEITDTSATVEVLVDADVTKDGETKTLKGVKVSVPVTISEDGKTVTVGTPTVTEG,0.41753954616702316,104.38488654175579,True,False,False,,86.20522534717749,0.18,0.31,0.33752 +209,G209,Generation_Rd1_48,LM,N/A,MKSLAENVAKEIEKRLKDKGYTVTSVSAGETSATITASKPGKPDLKIIVEVSGSTVKVRVEEGGKVVGEGTATVPPGTPPSEAVNKAVDEAIKKAEEKLK,0.31402878229989095,78.50719557497274,True,True,True,,87.296913956626,0.9,0.2,0.52248 +210,G210,Generation_Rd1_48,LM,N/A,MAELSASVSGKTLTATAKVTSTEDLKGAVLVITFVKADGSLAGVGGSEPVDIKAGESKDVTVTAENVPEGTTKVVAAVGQVTDLENLKPISDPVEVTITG,0.10715110741757516,26.78777685439379,True,False,False,,86.36463523027102,0.68,0.25,0.75625 +211,G211,Generation_Rd1_48,LM,N/A,MRISEAVRVATLKVLAENPEGLTVKELVEKVPKIVEEITGKPIKDVTSLRNSVSAALSRLSSKPPSPVVKAGEVTKDGRKYTVYKLTEEGKKLLEELEKR,0.15429707413853394,38.57426853463348,True,True,False,,88.44467056034608,0.9,0.22,0.71473 +212,G212,Generation_Rd2_Manual_24,LM,N/A,MAVAGTYKITSDIPGVGEATLTLKEDGSSVTGTLEVPAAGGSAEIKDGKVEGDKVSFTYTVNVPGQEPIEVKAELTVKDGKLSGTASTPFGDAPVSGEKA,0.13229364622976908,33.07341155744227,True,True,True,,86.99826238600645,3.2e-11,0.43,0.86711 +213,G213,Generation_Rd1_48,LM,N/A,METATEFVEAVIAGDYEKALELSAEQLQEGLTVEKLEEAKASLDAAGEYDSVGEPTTREDGGYTIVDVPVTLKDGSEVVLTVSIENESGKVAGLFVKPKE,0.27084891141880163,67.7122278547004,True,False,False,,86.5225409631302,7.2e-07,0.36,0.6981 +214,G214,Generation_Rd1_48,LM,N/A,MKVEISNVTVSGEGLDRNAVVSAVNSKKSSIEKAAKDAGVTSGTATVKLVIGSDGKVKSATASASGVSSSVASKIASEVKGLSFPSTGKETTVTIPFTLK,0.03139902999505464,7.849757498763659,False,False,False,,88.22988155893422,2.8e-05,0.34,0.88246 +215,G215,Generation_Rd1_48,LM,N/A,MTVAEKTLKNAAGQKVKAVLEASEDGSTGYVVITKAKDGKELDRVEISGEGLTDPEVSVSDADGGPVVTVTGTTAEGEPATFTVDLSKGKKPKVTETSAE,0.32056675575624544,80.14168893906135,True,False,False,,82.37853019011793,0.53,0.28,0.64831 +216,G216,Generation_Rd1_48,LM,N/A,MTLQEYIDKLKPSLEEGAKNAGSPIEKVEVKASDDGKSITATVTVKDGTPEDVIKGLVEGIGGSVLDSAKEAVPDAENVTLTVVGVSSSGKELARVTKTF,0.41491778749891783,103.72944687472946,True,True,True,,86.08404559468715,0.89,0.21,0.54895 +217,G217,Generation_Rd1_48,LM,N/A,MSITEEITKAVNEATSLSGSDPSKALEILKPVVEKAEKEGAPPLTVTRVKFVYATVASSVDKELAGKVLDEVIEDGKKLGESEPEVKDLVSAAENLKSTL,0.3071582954114238,76.78957385285595,True,True,True,,91.0878333852068,0.83,0.24,0.82118 +218,G218,Generation_Rd1_48,LM,N/A,MTQEELDRIEKELPPKVKAVPEVEDASVSLSISGGSTSLYTTVTAKEGLEGEALEKLAENVAGVVKDEITKSDIKDKYDSVTVSATTKDGKSGSKTIDLK,0.3570257326165188,89.25643315412971,True,False,False,,83.7127830370605,3.1,,0.57739 +219,G219,Generation_Rd1_48,LM,N/A,MSEETVKELTEISEGLSSGEEDVTATLEKLLPVIEDSSASDEAKVKALEITGDILENSADDVPPEVVSKIKSVVEPLKDGGSDAVKNAAGEVLDTIAEYQ,0.2836327323448656,70.9081830862164,True,False,False,,84.70923580434633,0.18,0.29,0.43856 +220,G220,Generation_Rd1_48,LM,N/A,MEITKEQLKEIIREAVKEVLEENKDIKAPEVSAKVEGDKVVVTVKPPSDADSVTLTVTPDGGSPITGEKKSDGTYEFTLSEPLKDGQKVTATATKDGKTS,0.3061561526382395,76.53903815955987,True,False,False,,86.83595052652292,0.17,0.33,0.50191 +221,G221,Generation_Rd1_48,LM,N/A,MATITKTATVTLDSPIKAGETVEKDVEVTGLPENAAGVSAVVASLSEDLKGKLTVSVLEAEISGTTAKFRVRITNVSGSDITPPAGSTSVTVKVTAIVEE,0.28516372438257664,71.29093109564415,True,True,True,,87.93084613994105,1.7,,0.55774 +222,G222,Generation_Rd1_48,LM,N/A,MPEFRVKLPPEKAAEIVERVLKEKYKDVTITSKSVSGGKAVIEGTKKGLLSSTTVKVTVEVSSDGTATVRAEPVGSLVSASKILEDIKNALREAGAEEVK,0.06549880772623917,16.374701931559795,True,True,False,,85.3883913690933,3.1,,0.77698 +223,G223,Generation_Rd2_Manual_24,LM,N/A,TPPAPPKASDFAGTYVGTDEEGEKVTVTLTVDAAGNVSGTAKDTEDSSEPVPLKGKVNADGKLEIVEDGEVVATGTLSADKKTLVIEAEGESEKITLTKQ,0.09947732072583444,24.86933018145861,True,False,False,,87.09331399353077,0.05,0.28,0.73171 +224,G224,Generation_Rd2_Manual_24,LM,N/A,KPEIKVSLDKDSVEIEAGKSAEVTVKVENVPEGTKVTLSVSGEGVSASLEPSEITPPGEAKLTITAGDKEGEYTVTVTATSSDGKTTGSKELKITVKKAE,0.28115350681597817,70.28837670399454,True,True,True,,90.74575985194588,8.2e-08,0.44,0.87605 +225,G225,Generation_Rd2_Manual_24,LM,N/A,MATVVRAEGEIDLDTAPELSEALEKAAGGSDGRPVVLDVSGVTFADSSFLNVLLRTHERVGKLVLAGTPPQVARLLEITGADKVLTVKDSVEEAVAAVSA,0.13122382806108723,32.80595701527181,True,True,False,,76.47276497468523,1.1e-19,0.55,0.83766 +226,G226,Generation_Rd2_Distant_57,LM,N/A,MVTATITVSASDPSKAEEVAKNVVTTKLTEKGYTVKDVRVSGDGKVTAVIEVTGGSEDEIKKAAENAAREAGEEAKKELEKEGLTVTSVEVKVEPPKPSS,0.18208726366160208,45.521815915400516,True,True,True,,87.55560444750809,10.0,,0.54279 +227,G227,Generation_Rd2_Distant_57,LM,N/A,MTPEEITKAVNDGLTEGLKGSPITDVKAEVTGEPPSFTVTATLTVSDSVSADEAKTILEGVAGGAAQALKDAGVTSGTVKVVGVRASDGKELASVEKPLS,0.20885437685969077,52.21359421492269,True,False,False,,85.7801244236998,0.21,0.23,0.44718 +228,G228,Generation_Rd2_Distant_57,LM,N/A,MSELLEKLKASLGSTVSVKVTREAKNAAGEPVKEVTEYTGKLSAVNEADGTITLTDVTVTKTTPPGPDGKPVVEKKETVEIPISSIESVTFTKDGQTVTA,0.3398507202768766,84.96268006921915,True,True,False,,86.87667869887674,1.0,,0.4184 +229,G229,Generation_Rd2_Distant_57,LM,N/A,MEKKTVTVSAAGESDPIVVPPGRPARVRATLTSSGTADVTLVSVPVKDGKPDDSKVLATITGLKAGETKELEIEAPEEGVAVKAKVTGGSASLTVEVEYE,0.25227839975840133,63.06959993960033,True,True,False,,87.79723699857843,0.067,0.23,0.46773 +230,G230,Generation_Rd2_Distant_57,LM,N/A,MVKDSATTLSTSVTDLTTAVGEGKSLEELKPLAETIKTSADTIVEKSKEIEGSEPVVEAANKLVEVSKVIADGGSLDDVKAKAGEVKTASDALVTAAGGK,0.2338792115122648,58.4698028780662,True,True,False,,90.34305763417996,0.39,0.25,0.70741 +231,G231,Generation_Rd2_Distant_57,LM,N/A,MDKKEFGAKVGEYGKLTVPVVKEPSAENVTKAGESVTGLVEAVNAADVSEEVKTSITTAAETLKSTIEGGGSKDEIKTAVIALRDATVAAGKELGVELPK,0.25967684498058474,64.91921124514619,True,True,False,,86.18377510050942,1.1,,0.52956 +232,G232,Generation_Rd2_Distant_57,LM,N/A,MAKIKVKVTGLPKGTKEVTVTAEYTPVDDEGNEGEPEVVAEAEKKNVKAGKSATFTLKDVPDGGSVTITASAVLADGTELSDSEEVEVSGKTVKLTLEEA,0.16627183065390522,41.56795766347631,True,False,False,,87.07187992662959,0.76,0.22,0.60576 +233,G233,Generation_Rd2_Distant_57,LM,N/A,MTKIEITGPITAENVQAVKDAIAKASGDVEVVISGTELDDGGADAVGEAIVEALEKGSKPVKVTVAAGSEPATILKEVLEEELKDLEGKKLSDRVSVSAA,0.22449890530402983,56.124726326007455,True,True,False,,85.88362975688092,0.87,0.22,0.64094 +234,G234,Generation_Rd2_Distant_57,LM,N/A,MSEISSKITELEGKDLSSAENVKAVGEYVSGTVVPKLEELAGKAPEGEVKTLVEKVASDAKALGEAGSAGDTAKVTEIVTKLKEDVTSLTTKVNELKPAA,0.31250271876593766,78.12567969148442,True,True,False,,85.75613746041445,0.13,0.21,0.69023 +235,G235,Generation_Rd2_Distant_57,LM,N/A,MSDPVKDAVSKIETAVTDLGTAIESGDKEKITSAGTTLTEASTSLKEAAGKLEGEKKTVVEGLSEKVTKAGELAKAEPVNVAELKPVFDEIKADIAKLKG,0.37075495020892035,92.6887375522301,True,True,True,,89.51803412698082,0.088,0.25,0.44611 +236,G236,Generation_Rd2_Distant_57,LM,N/A,MPEYIVTVDVAGGSREAVNKAAEKAKEIVEKVLSSKPGASLKDFRVSEPVEVSGVKVPSATLELVVEGEDAGKLAEEIKKTIESETGLTVISVTARPLKG,0.24397498074815135,60.99374518703784,True,True,True,,85.51463768596741,5.6,,0.62557 +237,G237,Generation_Rd2_Distant_57,LM,N/A,MATVSEIKTLLETAENKVEEAITAAGTDGGSDSGVKPILTEAKDAVTKAEGEATSPEVKELLEKAESKIEEAISAAGSDGGAKPVLTEAKDLVTQAEGKL,0.27265198104308813,68.16299526077204,True,True,False,,87.58504732555899,1.3,,0.49624 +238,G238,Generation_Rd2_Distant_57,LM,N/A,MEAENAKLTELEKKLPPEVKAVSADVTDVRVTATLKDGKYTGLIVTTTVKEGSDGGALGERIAGEITKVVKDSGVASEVGTPSVQVLDAAGKPLGSKTFG,0.1961497751760811,49.03744379402027,True,True,False,,86.26746860832306,0.79,0.23,0.45217 +239,G239,Generation_Rd2_Distant_57,LM,N/A,KAEEERKAKEAEEKRLAEIKKITDSVKSSVSGVTVGTPTEKDGKLVVPVTVSSASNAESTAKTVLTKLKDAGYTGEVIVEYKGSKVATSTLSGGSFTISK,0.15768906005559827,39.42226501389957,True,True,True,,85.66091734445378,0.75,0.26,0.44084 +240,G240,Generation_Rd2_Distant_57,LM,N/A,MSSSEITGLVTTLTESVKSLDGGSDLETATNAADTIKIIAETPENVGPLKDAGAVEAVKAVVTKLEELSGKEGVSDEDKTSAGEVLTVAKEALEVIEKAS,0.2445097638285768,61.1274409571442,True,True,False,,88.87406036196427,1.5,,0.46387 +241,G241,Generation_Rd2_Distant_57,LM,N/A,MSDDEIVEKLTAELKKSAENAAKDGGSPISGLITDVKVDRAGKTVTATVSESVPPEVSTAVGEVLAGVAGPVIKASDPSLEGYRVVVTGADGKELGSKDL,0.2825679200185735,70.64198000464337,True,True,True,,84.74036519803893,0.7,0.29,0.57643 +242,G242,Generation_Rd2_Distant_57,LM,N/A,MSESEIISSITSATSTLKSSSPSDADLVTALTTLEDTLVIAVNSGKPEFVKAAKDGGAVEAVKGVKERAEKAGEEGGSKEVVDRAGKVLELLEPPPAPSA,0.2989346108710877,74.73365271777192,True,True,True,,87.48056595556326,0.56,0.29,0.41786 +243,G243,Generation_Rd2_Distant_57,LM,N/A,MSITVTVKDGKVVISGDGGSKEVEGLDKLTETLKSEIEKAVKEGKPVKVTIEADSSVSEDDVNKIKTAAENAIKELKDKGELPSDAKVPENVEVKVEKKS,0.3876533576037763,96.91333940094407,True,True,True,,88.55976311534685,0.27,0.24,0.37726 +244,G244,Generation_Rd2_Distant_57,LM,N/A,MATVKEGVTSARDAVNKTLESLKAEPVDVEKVKADLTTAKDSVAKAKETAEKDGKPEVVTGLTELDASITKAGEAKTVEELRAALEPVSKSLSDLAGKLG,0.35559134729502334,88.89783682375584,True,True,True,,90.20816445050598,0.14,0.22,0.53916 +245,G245,Generation_Rd2_Distant_57,LM,N/A,MSIKSDIEAIVTKLNAATTPEEKKTVAGELSTKAGELKTSLEGKEVPENVKPVVTDLVEKVTALRDAAVKAKDGGADVSAEITAVQTSVTEISGKLEPLK,0.10007647042899974,25.019117607249935,True,False,False,,85.16136920836401,3.2,,0.76591 +246,G246,Generation_Rd2_Distant_57,LM,N/A,MSISEQVTEIKGLVTAIEGATSAEEVKTKAGELSTKIKELKDSVKDKVDGDLLTAVSDAGKALKEAGSKPDASLDDVKAAVTTATEKLNEVVAKLEPPAA,0.3820963191385863,95.52407978464659,True,True,True,,87.18511383337285,0.11,0.28,0.4967 +247,G247,Generation_Rd2_Distant_57,LM,N/A,MSEVISDLEKGKTLVTEAVNAGSPEEIKSKATEGLSVVESAIEKAKDVPGKETAVSLLEDGKKLITDAVAAGEAGNVDEVKRLASEGLTKVEEGIAALKG,0.3756393555782181,93.90983889455453,True,True,True,,93.67002727367768,2.5,,0.84527 +248,G248,Generation_Rd2_Manual_24,LM,N/A,MSEEIKKTITDLTEKVSGEPSAENVKAALPALKEGLENEDAGVRYRSVTAVGNIAEKAKDVPEVVEAVKELKPVLEKLSESDPDSTVRLRAKWALGKIEG,0.36140554984456064,90.35138746114016,True,True,True,,89.57056780347637,0.0084,0.37,0.77568 +249,G249,Generation_Rd2_Manual_24,LM,N/A,MEREVLRILKEAGFRVRRAAGSKGYDIVAEKDGKKYLIQVTSGKSPIKPEKVKELVEKAKAENAVPVIVTKTGRVSLPSEIEGVKVLTLEDLKKLLEESS,0.03994438270154638,9.986095675386593,False,False,False,,81.39408555233771,1e-05,0.35,0.73786 +250,G250,Generation_Rd2_Manual_24,LM,N/A,KVEASADKTTLKAGESTKLTVKVTPEGGKKVTITGLTAEGVKIEPSSVELPEVEPGKPVEVTFTVSAENATEGTKEITVTAKAEDGSEGSAKVSVTVEKK,0.2885688997753328,72.1422249438332,True,True,False,,89.35600792244621,0.02,0.33,0.85551 +251,G251,Generation_Rd2_Manual_24,LM,N/A,MANILVIGRVETITSTVKGLLEKEGYTVTTAVTDEEGIAKFKEAGKQDLVLISAGVSDPAEVERLTGEIKKVSSVPVVVHYDGGSKPEDIVADVKAALAK,0.3280431605407768,82.0107901351942,True,True,True,,84.67222933604307,1.2e-07,0.41,0.86648 +252,G252,Generation_Rd2_Manual_24,LM,N/A,MTVNSADDVKAAIEKAKSEGKTELVIGEGVTDEVLEEIAKETTITKVTLPSTVSVAGVEKLAENATGLTSITVPSSLSDEDKQKIKDAVTAKNGGSVTVG,0.2631119641538814,65.77799103847035,True,True,False,,88.24861387282598,0.025,0.27,0.58312 +253,G253,Generation_Rd2_Manual_24,LM,N/A,PDFELSAPPEVTVEKGKSAETTITVTAKDGFSDTVKLEASVSPSSGLTATLEPSEVKPGGSSKLTISTSSSTPVGEYTVTVTGTSGSLTKTKEIKVKVTE,0.339728702528489,84.93217563212225,True,True,True,,87.97385013811632,6.8e-14,0.53,0.86313 +254,G254,Generation_Rd2_Manual_24,LM,N/A,MTVTEKLSSDSVSERREAAEELAETAESDPESVTPEDVPGLIEALDDGSPVVRANAASALGEIGEPAKDAGAVERLTELKENDENSLVRVKAGKALEKIE,0.19252380707578953,48.130951768947384,True,False,False,,88.1057325229771,1.5e-06,0.4,0.7204 +255,G255,Generation_Rd2_Manual_24,LM,N/A,MSYTATVTITLSGVPSDKAGEAANKAKEIAENVAREKGLSASVRVSSISGGSVTVTLTVSAPSKEEAVKTAEEKVKPEIEKKLKDELGVEVTSVSVSEPS,0.2160377889856688,54.0094472464172,True,True,False,,88.04311436876847,0.043,0.25,0.74055 +256,G256,Generation_Rd2_Distant_57,LM,N/A,MPKFRVTVTLEVSAPEGTTPPSPSEIRDKVVEKLREAGASDVSVSTGYVGGKYTITATLTVEGSKEDAEKKAKETAENAVKEAVPGAEVKDVKVTKVEEL,0.3583463973557906,89.58659933894765,True,True,False,,88.59396840807321,1.3,,0.65086 +257,G257,Generation_Rd2_Manual_24,LM,N/A,MVKDGVTGLKEGVAKLKSEADSGGSVDTIKTTATDLKGKWDEIEPKVKEKSPEEYTKVETSIDELVKAAEAKDAATVKTKAGEVSTSLDAVITKLESASK,0.2574744851283073,64.36862128207682,True,False,False,,91.88966367944136,0.0001,0.34,0.92678 +258,G258,Generation_Rd2_Manual_24,LM,N/A,MKVAVEEGLTSVKKALEEAGFEVVSLDEVGEDVDAVVVRAGSAPPERVKEIIEKYKGKPVIVNASGRLAEIAKEYGVTAITGGSPSETVEKIKELLEKLK,0.27630556250521865,69.07639062630466,True,True,False,,86.07982206494033,0.00066,0.33,0.63824 +259,G259,Generation_Rd2_Manual_24,LM,N/A,MEELIKELESSDVEKRIEAVTKLSEIGPPAKDAVPSLVKLLKDEDSGVRAGTATVLGEIAETSPEVVKSAIPDLEKVSKTDENEYVRVAAENALKKITGK,0.36805364210366004,92.013410525915,True,True,True,,93.45533278402938,6e-09,0.47,0.89765 +260,G260,Generation_Rd2_Manual_24,LM,N/A,MKVKVTASGSVSSAKLRVTITPEDGGSPIVKEEEVSLSAGQTVEKEITLSEDDAKKLEGKKAKIKVEALDKDGNVVATGESDPVELKPGETKEVTVTLTK,0.4037847386394065,100.94618465985162,True,True,False,,90.01503428912336,1.8,,0.62789 +261,G261,Generation_Rd2_Distant_57,LM,N/A,MRIEEVVKLPLDEAFRVAKEAAENAGLKDVKVTSSTPTTITATGKSLVGSASVTVTLERVSDSETKVIVEGKPSGGLIGEKKARDAVNKVLEEIKRRAGG,0.14921872002077485,37.30468000519372,True,True,True,,87.86129988150013,0.44,0.22,0.73807 +262,G262,Generation_Rd2_Distant_57,LM,N/A,MAGVEAIKADVEKLKTAKPEEIVPLATSLKEKVDALVKEVEGLTVSAENKAKVTEAVTLIKSGADLVIEGTTSKDSAKISEGVTKVLEGITKILEVVAGK,0.4043522690967771,101.08806727419427,True,True,False,,91.76721563412217,0.048,0.26,0.77123 +263,G263,Generation_Rd2_Distant_57,LM,N/A,MSIKENIVKASESVSTAVTEAGKEPVNVETAKTSLTDAVTVLEGLVPELKADGKDDVATKLEEGVTKAKEGIEKVGSKDEVSAGLTTLSEAITAAGEALK,0.1432357725590353,35.808943139758824,True,False,False,,88.44608194385249,0.33,0.26,0.46556 +264,G264,Generation_Rd2_Distant_57,LM,N/A,MSEVETVKASIQEGIDAANKVSADGGSVAEIKTSLEPVVTKLTEAKGKSSDPKVTTLLDEAITAVNAVKPEEGADVATIKAGLTPVIEKLKEALALVPAA,0.35828339273400983,89.57084818350246,True,True,True,,86.91840993536144,0.33,0.3,0.74084 +265,G265,Generation_Rd2_Distant_57,LM,N/A,MSEIAGKVKEVVTKVEGVLSDSSKTPEEIKAAAGEVSTLVGEAVTAVSGKPGAESVATDLKNAADALKSAAEGGSKDGLTTAKTSLETAITKLTELANSL,0.32759017206237123,81.8975430155928,True,True,True,,92.24300254982056,2.9,,0.71623 +266,G266,Generation_Rd2_Manual_24,LM,N/A,PKIEEVSVSPSELKPGEKTTITAKISDPEGGSGIDTSSIKVEINGEDVTSKAKVEKVDENSATLTVEYTPPEPPLPPGKYTVTIRVKDKAGNEATETKEF,0.35890439604736646,89.72609901184161,True,True,True,,88.44787984007462,2.7e-05,0.41,0.75919 +267,G267,Generation_Rd2_Manual_24,LM,N/A,MTGAKVEPATAKPGDEVKVTATVNAAEEGEYTVSASLSGEGIGGSKSEPVKLEKGENEVTITLTVPEDAEAGKADVTSVSVTDKDGKRVASDSAPSFTVE,0.24711120672212794,61.77780168053199,True,False,False,,89.24986482953167,0.0055,0.38,0.70965 +268,,Fixed_Rd1_48,ground truth,1QYS,DIQVQVNIDDNGKNFDYTYTVTTESELQKVLNELMDYIKKQGAKRVRISITARTKKEAEKFAAILIKVFAELGYNDINVTFDGDTVTVEGQL,0.41197595017913285,102.99398754478321,True,False,False,0.8288429379463196,89.17377945545974,14.0,, +269,,Fixed_Rd1_48,ground truth,6CZJ,SALAQQLPGTWKMDVTSEDGVRTTGQMHIQPKTPTTMDVTLTGTHADGKPFTGQGKITVKTPTTVDITVTYEDGSTATGQLTVDSPTQFKFDMTASDGTRFTGTVQRQS,0.39017888440813564,97.5447211020339,True,True,True,1.0148541927337646,91.31992370254028,7.1,, +270,,Fixed_Rd1_48,ground truth,6W3W,DEDREWIERFNRILIESLTTGDEHTLKELIDPNARLVINGRDIHGREEFVRLLSEMGVKHFHVHDVKVVGNKAVTRGILYFNGREYDVDVFTRKIDGRWLYESLEVK,0.04445695864286616,11.11423966071654,False,False,False,1.4773865938186646,85.96058814924257,8.2,, +271,,Fixed_Rd1_48,ground truth,6WVS,DILIVNATDVDEMLKQVEILRRLGAKQIAVVSDDWRILQEALKKGGDILIVNATDVDEMLKQVEILRRLGAKQIAVVSDDWRILQEALKKGGDILIVNATDVDEMLKQVEILRRLGAKQIAVVSDDWRILQEALKKGGDILIVNATDVDEMLKQVEILRRLGAKQIAVVSDDWRILQEALKK,0.28575451397545437,71.43862849386359,True,True,True,0.8460836410522461,90.9020930370598,,, +272,,Fixed_Rd2_compare_LM_24,ground truth,5L33,PEEEKAARLFIEALEKGDPELMRKVISPDTRMEDNGREFTGDEVVEYVKEIQKRGEQWHLRRYTKEGNSWRFEVQVDNNGQTEQWEVQIEVRNGRIKRVTITHV,0.4303842742590548,107.5960685647637,True,True,True,,92.43271477764092,4.8,, +273,,Fixed_Rd2_compare_LM_24,ground truth,6D0T,MVDAAQYFPGTWEFRFRSSDGKEYRGTVEMQPRTPTEIEIRFKGQSSDGRPVEGRGSIEVRSPYEYRFEMQSSDGARWEGTLQVRSPDSVEVRFKSSDGREYSGEFRRQEG,0.401660220780138,100.41505519503451,True,False,False,,89.34978999176117,13.0,, +274,,Fixed_Rd2_compare_LM_24,ground truth,6MRS,GSGRQEKVLKSIEETVRKMGVTMETHRSGNEVKVVIKGLHESQQEQLKKDVEETSKKQGVETRIEFHGDTVTIVVRE,0.19924157322399905,49.81039330599976,True,False,False,,92.79344239462696,43.0,, +275,,Fixed_Rd2_compare_LM_24,ground truth,6NUK,GSTVRIEIRFTNMRREEVQKELEKFKERLKELEKRTGSEIRIEIEERDGEVRVEVEIRNSHEEEVRQIIEEIERWVRKMGGELRVEK,0.4075636222846284,101.89090557115709,True,True,True,,89.86144181933138,4.7,,0.38491 diff --git a/esm/source/examples/lm-design/paper-data/uniref90_jackhmmer_purge_ids.txt b/esm/source/examples/lm-design/paper-data/uniref90_jackhmmer_purge_ids.txt new file mode 100644 index 0000000000000000000000000000000000000000..0f173e8f5ae1b4ac11d1ed05a7cba3d201ffa94e --- /dev/null +++ b/esm/source/examples/lm-design/paper-data/uniref90_jackhmmer_purge_ids.txt @@ -0,0 +1,58462 @@ +UPI00006833D1 +UPI00071AFAB7 +UPI00034F232F +UPI0003C63F44 +UPI0000E5718E +A0A3S8SCX7 +UPI00017BDAF0 +A0A2I6BLH4 +A0A6C2C5F3 +A0A856MMD8 +UPI0004F13E6B +A0A7G8PVA7 +UPI00147C1656 +A0A6G6GKJ1 +A0A3Q3NFJ6 +UPI0015D95A5D +A0A3Q3T366 +A0A1R0GDY8 +UPI0018D2CA45 +A0A5E4ASG3 +A0A3Q3NFK3 +UPI0018D34449 +UPI000E45D2A6 +A0A2G9N366 +UPI000A4FEE25 +UPI000197ABDF +A0A809VTT6 +UPI000566AAEA +UPI001315A80D +A0A3Q8SB40 +I7JAE4 +A0A355KSG5 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b/esm/source/examples/lm-design/utils/constants.py @@ -0,0 +1,13 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from typing import Optional, NamedTuple +from enum import Enum + + +# Note ordering is important, correlates with Designer.py::coords[:, angle-index] +COORDS_ANGLE_NAMES = ['omega', 'theta', 'phi'] +COORDS4D_NAMES = ['dist'] + COORDS_ANGLE_NAMES +COORDS6D_NAMES = COORDS4D_NAMES + ['torsion_phi', 'torsion_psi'] diff --git a/esm/source/examples/lm-design/utils/fixedbb.py b/esm/source/examples/lm-design/utils/fixedbb.py new file mode 100644 index 0000000000000000000000000000000000000000..898aebfd414f3604c2c0bacd8b6f2cbe75955563 --- /dev/null +++ b/esm/source/examples/lm-design/utils/fixedbb.py @@ -0,0 +1,56 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import logging + +import torch +import torch.nn.functional as F +from torch.distributions import Bernoulli, OneHotCategorical +from tqdm import tqdm + + +logger = logging.getLogger(__name__) + + +@torch.no_grad() +def stage_fixedbb(self, cfg, disable_tqdm=False): + """Metropolis-Hastings sampling with uniform proposal and energy-based acceptance.""" + B, L, K = self.x_seqs.shape + + # import ipdb; ipdb.set_trace() + + itr = self.stepper(range(cfg.num_iter), cfg=cfg) + itr = tqdm(itr, total=cfg.num_iter, disable=disable_tqdm) + for step, s_cfg in itr: + x = self.x_seqs + a_cfg = s_cfg.accept_reject + + ############################## + # Proposal + ############################## + # Decide which position to mutate == {i}. + # mask 1 place + mask = torch.zeros((B, L, 1), dtype=torch.bool).to(x) # [B,L,1] + mask[:, torch.randint(0, L, (B,))] = True # [B,L,1] + mask = mask.bool() + + # Uniform proposal distribution. + log_p_x_i = torch.full((B, K), fill_value=-float("inf")).to(x) # [B, K] + log_p_x_i[..., self.vocab_mask_AA] = 0 # [B, K] + p_x_i = log_p_x_i.softmax(-1) + xp_i = OneHotCategorical(probs=p_x_i).sample() + xp = x.masked_scatter(mask, xp_i) # [B,L,K] + + ############################## + # Accept / reject + ############################## + # log A(x',x) = log P(x') - log P(x)) + # for current input x, proposal x', target distribution P and symmetric proposal. + log_P_x = self.calc_total_loss(x, mask, **a_cfg.energy_cfg)[0] # [B] + log_P_xp = self.calc_total_loss(xp, mask, **a_cfg.energy_cfg)[0] # [B] + log_A_xp_x = (-log_P_xp - -log_P_x) / a_cfg.temperature # [B] + A_xp_x = (log_A_xp_x).exp().clamp(0, 1) # [B] + A_bools = Bernoulli(A_xp_x).sample().bool() # [B] + self.x_seqs = torch.where(A_bools[:, None, None], xp, x) # [B,L,K] diff --git a/esm/source/examples/lm-design/utils/free_generation.py b/esm/source/examples/lm-design/utils/free_generation.py new file mode 100644 index 0000000000000000000000000000000000000000..a844be5b92d1983491b81ef611f7b6f964cf3e84 --- /dev/null +++ b/esm/source/examples/lm-design/utils/free_generation.py @@ -0,0 +1,94 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from pathlib import Path +from typing import List, Optional, Dict +import torch +import tree +from omegaconf import DictConfig + +from utils.scheduler import SchedulerSpec +from utils.tensor import assert_shape +import torch.nn.functional as F +from torch.distributions.categorical import Categorical +from utils.constants import COORDS4D_NAMES +from tqdm.auto import tqdm + +from utils.fixedbb import stage_fixedbb + + +def stage_free_generation( + designer, + num_iter: int, + resample_y_every: int, + stage_fixedbb_args: Optional[DictConfig] = None, + resample_y_temp: SchedulerSpec = 1.0, +): + assert resample_y_every < num_iter, \ + "resample_y_every must be smaller than num_iter, {} {}" \ + .format(resample_y_every, num_iter) + + _T_resample_y_temp = designer.init_schedulers(resample_y_temp=resample_y_temp)[0] + + def resample_y(): + x_seq = designer.x_seqs + struct_preds = designer.struct_model(x_seq) + + def sample_logits(preds, logits_name): + logits = preds[logits_name] + logits /= _T_resample_y_temp() + + # Alter preds from logits that were changed by temp (for logging after) + distangle_key_name = logits_name.replace('_logits', '') + preds[f'p_{distangle_key_name}'] = logits.softmax(-1) + preds[logits_name] = logits + + sampled_map = Categorical(logits=logits).sample() + return sampled_map + + # sample structure (dist and angles) bins from logits + sampled_dist_and_angles = [] + for coord_name in COORDS4D_NAMES: + sampled = sample_logits(struct_preds, f'{coord_name}_logits') + sampled_dist_and_angles.append(sampled) + sampled_dist_and_angles = torch.stack(sampled_dist_and_angles, dim=1) + + # Logits B x L x L x K; first 3 dims are treated as batch dims: + set_target_structure(designer, sampled_dist_and_angles) + + curr_step = 0 + pbar = tqdm(total=num_iter, desc='stage_hallucination_joint_mh') + while curr_step < num_iter: + resample_y() + + # do resample_y_every steps of gibbs p(seq|struct) sampling + num_iter_mh = resample_y_every + stage_fixedbb_args['num_iter'] = num_iter_mh + stage_fixedbb(designer, stage_fixedbb_args, disable_tqdm=True) + # Set this flag to true so inner schedulers at stage_fixedbb will keep state between calls + designer.resuming_stage = True + curr_step += num_iter_mh + pbar.update(num_iter_mh) + +def set_target_structure(designer, sampled_dist_and_angles): + """ + Set the given sampled contacts as the target structure in designer. This allows designing + a sequence for that structure later. + """ + + assert sampled_dist_and_angles.shape[0] == 1, "Only single-batch supported for now" + if hasattr(designer, 'coords'): + assert designer.coords.shape == sampled_dist_and_angles.shape + + # Coords is [B=1, 4, L, L] + designer.coords = sampled_dist_and_angles + + cutoff_bin_max = designer.pdb_loader_params['contact_bin_cutoff'][1] + # Use resnet predictons to determine the + designer.target_contacts = (designer.coords[:, 0] <= cutoff_bin_max).squeeze(0) + + designer.target_no_contacts = ~designer.target_contacts + # TEMP; assume Batchdim==1 (also for gibbs). + assert_shape(designer.target_contacts, designer.L, designer.L) diff --git a/esm/source/examples/lm-design/utils/linear_projection.py b/esm/source/examples/lm-design/utils/linear_projection.py new file mode 100644 index 0000000000000000000000000000000000000000..927eab2e63076ffaab7127512b5f1f4c094befa7 --- /dev/null +++ b/esm/source/examples/lm-design/utils/linear_projection.py @@ -0,0 +1,138 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. +# +import logging +from collections import defaultdict +from functools import partial +from pathlib import Path +import torch +import torch.nn.functional as F +import torch.nn as nn +from collections import namedtuple + +import os +import sys +import torch +from pathlib import Path +from argparse import Namespace +from omegaconf import DictConfig, OmegaConf +from typing import Dict, Optional, List, Callable, Union +import math + +BinningScheme = namedtuple( + 'BinningScheme', + [ + 'N_BINS', + 'CUTOFF_BIN', + 'MIN_DIST', + 'MAX_DIST', + 'CONTACT_DIST', + 'THETA_BINS', + 'PHI_BINS', + 'OMEGA_BINS', + 'TORSION_BINS', + ], +) +LinearProjectionDist_1A = BinningScheme( + N_BINS=18, + CUTOFF_BIN=5, # conservative cutoff for 8 angstroms exact ((20-2.5)/16*5 + 2.5 = ~7.9) + MIN_DIST=2.5, + MAX_DIST=20, + CONTACT_DIST=8, + THETA_BINS=18, + PHI_BINS=8, + OMEGA_BINS=18, + TORSION_BINS=50, +) +BIN_FLAG_TO_ENUM = { + 'LinearProjectionDist_1A': LinearProjectionDist_1A, +} + +logger = logging.getLogger(__name__) + + +def extract_features( + model, + inp: torch.Tensor, + has_cls: bool = True, + has_eos: bool = True, + need_head_weights: Union[bool, Dict] = False, +): + """ + Inflexible way of dealing with the mess of inputs with cls tokens, + need embedding without, and LSTM doesnt want cls token in the first place. + """ + + out_start_idx = 1 if has_cls else 0 + out_end_idx = -1 if has_eos else None + inp = inp.argmax(dim=-1) # output [B, T] + result = model(inp, need_head_weights=need_head_weights) + attentions = result["attentions"] + + batch, layer, head, seqlen, seqlen2 = attentions.size() + assert seqlen == seqlen2 + attentions = attentions.reshape( + batch, layer * head, seqlen, seqlen + ) + emb = result["logits"] + + return emb[:, out_start_idx:out_end_idx], \ + attentions[:, :, out_start_idx:out_end_idx, out_start_idx:out_end_idx] + + +class LinearProjectionDistogramModel(nn.Module): + """ + This model regresses angles and distances from the attention maps of the LM + """ + + def __init__(self): + super().__init__() + self.base_model = None # To be initialized later + self.num_heads = 20 * 33 + self.bin_enum = BIN_FLAG_TO_ENUM['LinearProjectionDist_1A'] + self._s1 = self.bin_enum.N_BINS + self._s2 = self._s1 + self.bin_enum.THETA_BINS + self._s3 = self._s2 + self.bin_enum.PHI_BINS + self._s4 = self._s3 + self.bin_enum.OMEGA_BINS + + conv_in_channels = self.num_heads + + self.conv1 = torch.nn.Conv2d( + in_channels=conv_in_channels, + out_channels=self.bin_enum.N_BINS + self.bin_enum.OMEGA_BINS, + kernel_size=1, + stride=1, + padding=0, + ) + + self.conv2 = torch.nn.Conv2d( + in_channels=conv_in_channels, + out_channels=self.bin_enum.THETA_BINS + self.bin_enum.PHI_BINS, + kernel_size=1, + stride=1, + padding=0, + ) + + + def forward(self, src_tokens, **kwargs): + _, attentions_asym = extract_features(self.base_model, src_tokens, need_head_weights=True) + + def symmetrize(contacts, scale=1.0): + return scale * (contacts + contacts.transpose(-1, -2)) + + attentions_sym = symmetrize(attentions_asym) + + # [B, C, N, N] -> [B, output_channels, N, N] + out1 = self.conv1(attentions_sym) + out2 = self.conv2(attentions_asym) + return { + 'logits': out1[:, :self.bin_enum.N_BINS:, :, :], + 'omega_logits': out1[:, self.bin_enum.N_BINS:, :, :], + 'theta_logits': out2[:, :self.bin_enum.THETA_BINS, :, :], + 'phi_logits': out2[:, self.bin_enum.THETA_BINS:, :, :], + } + + + diff --git a/esm/source/examples/lm-design/utils/lm.py b/esm/source/examples/lm-design/utils/lm.py new file mode 100644 index 0000000000000000000000000000000000000000..35a7705151462e80b629c447e7e06ab623c72e52 --- /dev/null +++ b/esm/source/examples/lm-design/utils/lm.py @@ -0,0 +1,102 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import logging +import math +logger = logging.getLogger(__name__) +from typing import Optional, Dict, List, Any, Union + +import torch +from torch import nn +import torch.nn.functional as F +from abc import ABC, abstractmethod + +from .tensor import is_1hot_tensor, add_eos_bos +from .masking import apply_mask, assert_valid_mask + + +def lm_marginal(mlm, x, mask): + """ + Utility to extract logprobs from an MLM, given an input tensor and a mask. + NOTE: + - **Mask each set bit in mask's L-dim separately.** - (as opposed to all at once.) + - Therefore, performs B*n forward passes. + - In the future, we might try just using a single forward pass per sequence = B passes. + - We had some success with something akin to this in the ESM-1V paper. + Args: + x: [B, L, K] + mask: [B, L, 1] # n masks in L dim + if None, use a mask of all ones. + Returns: + logits: [B, n, K] + """ + B, L, K = x.shape + if mask is None: + mask = torch.ones(B, L, 1, dtype=torch.bool, device=x.device) + n = assert_valid_mask(mask, x=x) # this is gross. + + # Get coords of set bits. [B*n] + b_coords, l_coords, _ = mask.nonzero(as_tuple=True) # [B*n], [B*n] + # Double-check of mask assumptions. + assert torch.equal(b_coords, torch.repeat_interleave(torch.arange(B).to(x.device), n).to(x.device)) + + # naming: _m1 = mask1. (B*n leading dim.) + x_m1 = x[b_coords] # [B*n, L, K] + mask_m1 = F.one_hot(l_coords, L).unsqueeze(-1).bool() # [B*n, L, 1] + + # Apply mask, mlm forward, select logits. + x_masked_m1 = apply_mask(x_m1, mask_m1, mlm.vocab.mask_idx) # [B*n, L, K] + lm_logits_m1 = mlm(x_masked_m1)['logits'] + lm_logits_select = lm_logits_m1.masked_select(mask_m1).reshape(B, n, K) # [B, n, K] + + # Mlm outputs 'logits' = not logprobabilities, but pre-softmax values. + # We must log-softmax here to convert from pre-softmax logits -> logprobs. + lm_logprobs_select = torch.log_softmax(lm_logits_select, axis=-1) + + return lm_logprobs_select # [B, n, K] + + +class WrapLM(nn.Module, ABC): + def __init__(self, LM, vocab): + super().__init__() + self.model = LM + self.vocab = vocab + + @abstractmethod + def forward(self, seq1h, **kwargs): + raise NotImplementedError + + +class WrapLmEsm(WrapLM): + def forward(self, seq1h): + B, L, K = seq1h.shape + seq1h, seq_start_idx, seq_end_idx = self._prepare_seq(seq1h) + seq = seq1h.argmax(-1) + + out = self.model(seq) + + return { + 'logits': out['logits'][:, seq_start_idx:seq_end_idx, :K], + } + + def _prepare_seq(self, seq1h): + assert is_1hot_tensor(seq1h) + B, L, K = seq1h.shape + # Prepend bos/cls and append eos. + seq1h = add_eos_bos(seq1h, bos_idx=self.vocab.cls_idx, eos_idx=self.vocab.eos_idx) + seq_start_idx = 1 + seq_end_idx = L + 1 + + # In some cases, a vocab padded to 64 positions + # with dummy character was used. + # As a workaround, pad K dimension, then remove this portion after + embed_dim = self.model.embed_tokens.weight.size(0) + if embed_dim != K: + seq1h = torch.cat([ + seq1h, + torch.zeros(B, L+2, embed_dim - K).to(seq1h) + ], -1) + + return seq1h, seq_start_idx, seq_end_idx diff --git a/esm/source/examples/lm-design/utils/loss.py b/esm/source/examples/lm-design/utils/loss.py new file mode 100644 index 0000000000000000000000000000000000000000..2465016f195bf8658b26735ac854a260293ab9a9 --- /dev/null +++ b/esm/source/examples/lm-design/utils/loss.py @@ -0,0 +1,29 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import torch +import torch.nn.functional as F + + +def get_cce_loss(probs, labels, mask=None, eps=1e-8,): + """ + Calculates the categorical cross entropy and averages result. + Using optional mask to control which labels are included in the loss. + Args: + probs (torch.float32): [B, L, L, num_categories] + labels (torch.int32): [B, L, L] + mask (torch.float32): [B, L, L] + Returns: + average_cce (torch.float32): [B] + """ + if mask is None: + B, L = probs.shape[:2] + mask = torch.ones(B, L, L).to(probs.device) + + num_categories = probs.shape[-1] + labels_onehot = F.one_hot(labels, num_categories) + cce_ij = -torch.sum(labels_onehot * torch.log(probs+eps), axis=-1) + average_cce = torch.sum(mask * cce_ij, axis=(1, 2)) / torch.sum(mask, axis=(1, 2)) + return average_cce diff --git a/esm/source/examples/lm-design/utils/masking.py b/esm/source/examples/lm-design/utils/masking.py new file mode 100644 index 0000000000000000000000000000000000000000..fce04dab256b442d6b22fb985941668ca58c74c7 --- /dev/null +++ b/esm/source/examples/lm-design/utils/masking.py @@ -0,0 +1,92 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from typing import Union + +import torch +import torch.nn.functional as F +from .tensor import ( + assert_shape, + is_1hot_tensor, +) + + +def apply_mask(x, mask, mask_tok_idx): + """ + Args: + x (torch.float32): [*, K] + mask (torch.float32): [*, 1] + mask_tok_idx (int): vocab index for mask token + Returns: + x_masked (torch.float32): [*, K] = x, + with mask_tok_idx inserted, where mask == 1. + """ + assert is_1hot_tensor(x) + K = x.size(-1) + x_masked = x.detach().clone() + x_masked[mask.squeeze(-1)] = F.one_hot(torch.tensor(mask_tok_idx), K).to(x) + return x_masked + + +def assert_valid_mask(mask, x=None): + """ + Utility that checks if a mask is [B, L, 1], given + an optional tensor the mask might apply to, of size [B, L, K] + This utility also returns the number of set bits in the mask, in the L dim == n. + n is useful to know, because: + x_masked = x.masked_select(mask) + x: [B, L, K] + mask: [B, L, 1] + x_masked: [B, n, K] + """ + if x is not None: + assert x.dtype == torch.float, x.dtype + assert x.ndim == 3, x.ndim + assert mask.shape[:2] == x.shape[:2], (mask.shape[:2], x.shape[:2]) + assert mask.dtype == torch.bool + num_masks_per_b = mask.sum(1) + assert (num_masks_per_b[0] == num_masks_per_b).all() + return num_masks_per_b[0] + + +def masked_insert_from_tokens(x, insert_mask, insert_toks): + """ + [B, L, K] -> [B, I, L, K] + x contains n masks per row. + I is a new inserted dimension made + by duplicating each [L, K] seq in [B] [I] times. + Inserted tokens come from [B, I, n] insert_toks tensor. + If insert_toks is [I, n], will broadcast. + This is most helpful for gibbs: + producing proposal seqs over AA_vocab. + len(AA_vocab)**n for n-site gibbs. + Args: + x (torch.float32): [B, L, K] + insert_mask (torch.bool): [B, L, 1] + indicating which positions to insert tokens in newly created I dim. + insert_toks (torch.float32): [(B?), I, mask_count=n] + Returns: + x_filled (torch.float32): [B, I, L, K] + """ + B, L, K = assert_shape(x, -1, -1, -1) + n = assert_valid_mask(insert_mask) + if insert_toks.dim() == 2: + I = assert_shape(insert_toks, -1, n) # [I, n] + insert_toks = insert_toks.unsqueeze(0).repeat(B, 1, 1) # [B, I, n] + else: + I = assert_shape(insert_toks, B, -1, n) # [B, I, n] + + # 1hot -> dense (remove the need for these.) + x_idx = x.argmax(-1) # [B, L] + insert_mask = insert_mask.squeeze(-1) # [B, L] + + # Open up insert dim + x_idx = x_idx.unsqueeze(1).repeat(1, I, 1) # [B, I, L] + insert_mask = insert_mask.unsqueeze(1).repeat(1, I, 1) # [B, I, L] + x_idx[insert_mask] = insert_toks.flatten() # [B, I, n] + + # dense -> 1hot + x = F.one_hot(x_idx, K).to(x) # [B, I, L, K] + return x diff --git a/esm/source/examples/lm-design/utils/misc.py b/esm/source/examples/lm-design/utils/misc.py new file mode 100644 index 0000000000000000000000000000000000000000..ea9c647700055ba3e16317e9e7818e7db0fc7a36 --- /dev/null +++ b/esm/source/examples/lm-design/utils/misc.py @@ -0,0 +1,41 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. +import math +import sys +from contextlib import AbstractContextManager, contextmanager +import inspect +import logging +import os +from pathlib import Path +import pickle +import socket +import time + +logger = logging.getLogger(__name__) + + + +class TimerContext(AbstractContextManager): + """ + Used to measure time and log if time threshold passed. + Usage: + with TimerContext(tag="disk usage", theshold=10.0) as tc: + some_long_operation() # will log warning in case this takes more than 10 seconds + print(tc.elapsed) # elapsed data-member contains elapsed time in secs + """ + def __init__(self, tag="N/A", threshold=None): + super().__init__() + self.tag = tag + self.threshold = threshold + + def __enter__(self): + self.start = time.time() + return self + + def __exit__(self, exc_type, exc_val, exc_tb): + self.elapsed = (time.time() - self.start) + self.elapsed_rounded = round(self.elapsed, 2) + if self.threshold is not None and self.elapsed > self.threshold: + logger.warning(f"Timer passed threshold: {self.tag} -- {self.elapsed_rounded}") diff --git a/esm/source/examples/lm-design/utils/ngram.py b/esm/source/examples/lm-design/utils/ngram.py new file mode 100644 index 0000000000000000000000000000000000000000..b001527f82705da1b9bf7e770d0595e77d4fae9e --- /dev/null +++ b/esm/source/examples/lm-design/utils/ngram.py @@ -0,0 +1,73 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. +# +from collections import Counter +from pathlib import Path +import pickle +import random +import time + +from nltk import ngrams +import numpy as np + + +# Code for loading constants for preprocessing +seq_encode = ['L', 'A', 'G', 'V', 'S', 'E', 'R', 'T', 'I', 'D', 'P', 'K', 'Q', 'N', 'F', 'Y', 'M', 'H', 'W', 'C'] +BASE = Path('./utils/ngram_stats/') +ngram_list = [] +for fn in ["monogram_seg.p", "bigram_seg.p", "trigram_seg.p", "quadgram_seg.p"]: + with open(BASE / fn, "rb") as f: + ngram_list.append(pickle.load(f)) + +# Recompute ngram frequency based off the valid sequences used for design +for i, ngram_dict in enumerate(ngram_list): + idx_dict = {} + for k, v in ngram_dict.items(): + ids = [] + error = False + + for ki in k: + if ki not in seq_encode: + error = True + break + id = seq_encode.index(ki) + ids.append(id) + + if error: + continue + + ids = tuple(ids) + idx_dict[ids] = v + + total = sum(idx_dict.values()) + # Min value for ngram is 1e-5 + idx_dict = {k: max(v / total, 1e-5) for k, v in idx_dict.items()} + + ngram_list[i] = idx_dict + +def encode(seq): + if isinstance(seq, np.ndarray): + return seq # already encoded + elif isinstance(seq, str): + return np.array([seq_encode.index(AA) for AA in seq]) + else: + raise ValueError(f'Unknown seq type {seq}') + + +def compute_kl_div(seq, order): + # Inputs Args: + # Seq: N dimensional numpy array consisting of numbers between 0 and 19 (inclusive) + # Order: integer for order of ngram used (should be between 0 and 3 for now) + order_dict = ngram_list[order-1] + seq = encode(seq) # this is not the problem. + + # Compute ngram frequency rate for the input sequence + tup_dict = Counter(ngrams(seq,n=order)) + total = sum(tup_dict.values()) + tup_dict = {k: v / total for k, v in tup_dict.items()} + + p = np.array(list(tup_dict.values())) # observed probabilities of ngrams + q = np.array([order_dict.get(k, 1e-5) for k in tup_dict.keys()]) # learned ngram probabilities + return np.sum(p * np.log(p/q)) diff --git a/esm/source/examples/lm-design/utils/ngram_stats/bigram_seg.p b/esm/source/examples/lm-design/utils/ngram_stats/bigram_seg.p new file mode 100644 index 0000000000000000000000000000000000000000..46e831496d6a583c1a9cee9062576e8da25ec517 --- /dev/null +++ b/esm/source/examples/lm-design/utils/ngram_stats/bigram_seg.p @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d1832ddfd7af47f28575d2ef1369846995655b05cad00358b8bf885399a47d19 +size 8861 diff --git a/esm/source/examples/lm-design/utils/ngram_stats/monogram_seg.p b/esm/source/examples/lm-design/utils/ngram_stats/monogram_seg.p new file mode 100644 index 0000000000000000000000000000000000000000..00ddb66fd93641f9480808de79dba70585b550c1 --- /dev/null +++ b/esm/source/examples/lm-design/utils/ngram_stats/monogram_seg.p @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:27a06a492dbdefe29aa63b55d2f9639368ccafd884001ce3f16ef110017ca850 +size 382 diff --git a/esm/source/examples/lm-design/utils/ngram_stats/quadgram_seg.p b/esm/source/examples/lm-design/utils/ngram_stats/quadgram_seg.p new file mode 100644 index 0000000000000000000000000000000000000000..040e20edeaebd5147b9e1de97469cb1de0c0a4c1 --- /dev/null +++ b/esm/source/examples/lm-design/utils/ngram_stats/quadgram_seg.p @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c836b3105fcef0bf8ba4a8758649b5b799b4e75a3630cd9463cda0964927c066 +size 196247 diff --git a/esm/source/examples/lm-design/utils/ngram_stats/trigram_seg.p b/esm/source/examples/lm-design/utils/ngram_stats/trigram_seg.p new file mode 100644 index 0000000000000000000000000000000000000000..040e20edeaebd5147b9e1de97469cb1de0c0a4c1 --- /dev/null +++ b/esm/source/examples/lm-design/utils/ngram_stats/trigram_seg.p @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c836b3105fcef0bf8ba4a8758649b5b799b4e75a3630cd9463cda0964927c066 +size 196247 diff --git a/esm/source/examples/lm-design/utils/pdb_loader.py b/esm/source/examples/lm-design/utils/pdb_loader.py new file mode 100644 index 0000000000000000000000000000000000000000..81b82227f137d7f1e639311253b9536f7dd42e83 --- /dev/null +++ b/esm/source/examples/lm-design/utils/pdb_loader.py @@ -0,0 +1,321 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. +# +# Portions of this file were adapted from the open source code +# https://github.com/RosettaCommons/trRosetta2/tree/main +# Modifications were made to loader() and get_coords6d() functions: +# 1. addition of `set_diagonal` flag. +# 2. addition of `allow_missing_residue_coords` flag. +# Original License information below. + +# MIT License + +# Copyright (c) 2021 Ivan Anishchenko, Minkyung Baek, Naozumi Hiranuma, Ian Humphrey + +# Permission is hereby granted, free of charge, to any person obtaining a copy +# of this software and associated documentation files (the "Software"), to deal +# in the Software without restriction, including without limitation the rights +# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +# copies of the Software, and to permit persons to whom the Software is +# furnished to do so, subject to the following conditions: + +# The above copyright notice and this permission notice shall be included in all +# copies or substantial portions of the Software. + +# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +# AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +# OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE +# SOFTWARE. + +import numpy as np +import scipy +import scipy.spatial +import logging + +logger = logging.getLogger(__name__) + + +PDB_LOADER_PARAMS_DEFAULT = { # trRosetta-v2 + "DMIN" : 2.0, + "DMAX" : 20.0, + "DBINS" : 36, + "ABINS" : 36, + "WMIN" : 0.8, + "LMIN" : 150, + "LMAX" : 400, + "EPOCHS" : 10, + "NCPU" : 8, + "SLICE" : "CONT", + "contact_bin_cutoff": (0, 11) # both inclusive +} + + +# calculate dihedral angles defined by 4 sets of points +def get_dihedrals(a, b, c, d): + + b0 = -1.0*(b - a) + b1 = c - b + b2 = d - c + + b1 /= np.linalg.norm(b1, axis=-1)[:,None] + + v = b0 - np.sum(b0*b1, axis=-1)[:,None]*b1 + w = b2 - np.sum(b2*b1, axis=-1)[:,None]*b1 + + x = np.sum(v*w, axis=-1) + y = np.sum(np.cross(b1, v)*w, axis=-1) + + return np.arctan2(y, x) + + +# calculate planar angles defined by 3 sets of points +def get_angles(a, b, c): + + v = a - b + v /= np.linalg.norm(v, axis=-1)[:,None] + + w = c - b + w /= np.linalg.norm(w, axis=-1)[:,None] + + x = np.sum(v*w, axis=1) + + return np.arccos(x) + + +def nonans(arr): + return not (arr != arr).any() + + +# get 6d coordinates from x,y,z coords of N,Ca,C atoms +def get_coords6d(xyz, dmax, allow_missing_residue_coords=False): + + nres = xyz.shape[1] + # three anchor atoms + N = xyz[0] + Ca = xyz[1] + C = xyz[2] + if not nonans(xyz): + assert allow_missing_residue_coords, "Missing residue coordinates" + logger.warning("PDB xyz contains NaNs!! Loading anyway...") + # recreate Cb given N,Ca,C + b = Ca - N + c = C - Ca + a = np.cross(b, c) + Cb = -0.58273431*a + 0.56802827*b - 0.54067466*c + Ca + + # fast neighbors search to collect all + # Cb-Cb pairs within dmax + kdCb = scipy.spatial.cKDTree(Cb) + indices = kdCb.query_ball_tree(kdCb, dmax) + + # indices of contacting residues + idx = np.array([[i,j] for i in range(len(indices)) for j in indices[i] if i != j]).T + idx0 = idx[0] + idx1 = idx[1] + + # Cb-Cb distance matrix + dist6d = np.full((nres, nres), 999.9) + dist6d[idx0,idx1] = np.linalg.norm(Cb[idx1]-Cb[idx0], axis=-1) + + # matrix of Ca-Cb-Cb-Ca dihedrals + omega6d = np.zeros((nres, nres)) + omega6d[idx0,idx1] = get_dihedrals(Ca[idx0], Cb[idx0], Cb[idx1], Ca[idx1]) + + # matrix of polar coord theta + theta6d = np.zeros((nres, nres)) + theta6d[idx0,idx1] = get_dihedrals(N[idx0], Ca[idx0], Cb[idx0], Cb[idx1]) + + # matrix of polar coord phi + phi6d = np.zeros((nres, nres)) + phi6d[idx0,idx1] = get_angles(Ca[idx0], Cb[idx0], Cb[idx1]) + + if nonans(xyz): + # Set dist values to nan where there's no pdb 3d coordinates data + nan_residues = ((Cb != Cb).sum(-1) > 0) + nan_residues_mask = (nan_residues[None] | nan_residues[None].T) + dist6d[nan_residues_mask] = np.nan + omega6d[nan_residues_mask] = np.nan + theta6d[nan_residues_mask] = np.nan + phi6d[nan_residues_mask] = np.nan + + return dist6d, omega6d, theta6d, phi6d + + +def parse_PDB(pdb_path, atoms=['N','CA','C'], chain=None, return_aligned_seq=False): + ''' + input: pdb_path = PDB filename + atoms = atoms to extract (optional) + output: (length, atoms, coords=(x,y,z)), sequence + ''' + xyz,seq,doubles,min_resn,max_resn = {},{},{},np.inf,-np.inf + with open(pdb_path,"rb") as f: + for line in f: + line = line.decode("utf-8","ignore").rstrip() + + if line[:6] == "HETATM" and line[17:17+3] == "MSE": + line = line.replace("HETATM","ATOM ") + line = line.replace("MSE","MET") + + if line[:4] == "ATOM": + ch = line[21:22] + if ch == chain or chain is None: + atom = line[12:12+4].strip() + resi = line[17:17+3] + resi_extended = line[16:17 + 3].strip() + resn = line[22:22+5].strip() + x,y,z = [float(line[i:(i+8)]) for i in [30,38,46]] + + if resn[-1].isalpha(): resa,resn = resn[-1],int(resn[:-1])-1 + else: resa,resn = "",int(resn)-1 + if resn < min_resn: min_resn = resn + if resn > max_resn: max_resn = resn + if resn not in xyz: xyz[resn] = {} + if resa not in xyz[resn]: xyz[resn][resa] = {} + if resn not in seq: seq[resn] = {} + if resa not in seq[resn]: + seq[resn][resa] = resi + elif seq[resn][resa] != resi_extended: + # doubles mark locations in the pdb file where multi residue entries are + # present. There's a known bug in TmAlign binary that doesn't read / skip + # these entries, so we mark them to create a sequence that is aligned with + # gap tokens in such locations. + doubles[resn] = True + + if atom not in xyz[resn][resa]: + xyz[resn][resa][atom] = np.array([x,y,z]) + + # convert to numpy arrays, fill in missing values + seq_,xyz_,aligned_seq_ = [],[],[] + for resn in range(min_resn,max_resn+1): + if resn in seq: + for k in sorted(seq[resn]): + seq_.append(aa_3_N.get(seq[resn][k],20)) + aligned_seq_.append(seq_[-1]) if resn not in doubles else aligned_seq_.append(20) + else: + seq_.append(20) + if resn in xyz: + for k in sorted(xyz[resn]): + for atom in atoms: + if atom in xyz[resn][k]: xyz_.append(xyz[resn][k][atom]) + else: xyz_.append(np.full(3,np.nan)) + else: + for atom in atoms: xyz_.append(np.full(3,np.nan)) + + res = [np.array(xyz_).reshape(-1,len(atoms),3), N_to_AA(np.array(seq_))] + if return_aligned_seq: + res += [N_to_AA(np.array(aligned_seq_))] + return res + +def N_to_AA(x): + # [[0,1,2,3]] -> ["ARND"] + x = np.array(x); + if x.ndim == 1: x = x[None] + return ["".join([aa_N_1.get(a,"-") for a in y]) for y in x] + +alpha_1 = list("ARNDCQEGHILKMFPSTWYV-") +alpha_3 = ['ALA','ARG','ASN','ASP','CYS','GLN','GLU','GLY','HIS','ILE', + 'LEU','LYS','MET','PHE','PRO','SER','THR','TRP','TYR','VAL','GAP'] + +aa_3_N = {a:n for n,a in enumerate(alpha_3)} +aa_N_1 = {n:a for n,a in enumerate(alpha_1)} + +def loader(pdb_path, params, chain=None, set_diagonal=False, allow_missing_residue_coords=False): + """ + Args: + pdb_path: path to pdb file + params: dict with hyperparams + chain: + set_diagonal: sets diagonal to specific default values. + """ + orig_xyz, seq = parse_PDB(pdb_path, atoms=['N','CA','C'], chain=None) + xyz = np.transpose(orig_xyz, (1,0,2)) + idx = np.arange(xyz.shape[1]) + # get 6D coords + d,o,t,p = get_coords6d(xyz, params['DMAX'], allow_missing_residue_coords) + no_angles = any([np.isnan(x).any() for x in [o,t,p]]) + + # bin 6D coords + if params['DMIN'] == 2.5: + dbins = np.linspace(params['DMIN'], params['DMAX'], params['DBINS']) + else: + dstep = (params['DMAX'] - params['DMIN']) / params['DBINS'] + dbins = np.linspace(params['DMIN'] + dstep, params['DMAX'], params['DBINS']) + + angle_step = 2.0 * np.pi / params['ABINS'] + ab360 = np.linspace(-np.pi + angle_step, np.pi, params['ABINS']) + phi_last_bin = int(params['ABINS']/2) + if "PHI_BINS" in params: + phi_last_bin = params['PHI_BINS'] + ab180 = np.linspace(angle_step, np.pi, phi_last_bin) + + db = np.digitize(d, dbins).astype(np.uint8) # distance + ob = np.digitize(o, ab360).astype(np.uint8) # omega + tb = np.digitize(t, ab360).astype(np.uint8) # theta + pb = np.digitize(p, ab180).astype(np.uint8) # phi + + # synchronize 'no contact' bins + ob[db == params['DBINS']] = params['ABINS'] + tb[db == params['DBINS']] = params['ABINS'] + pb[db == params['DBINS']] = phi_last_bin + + if set_diagonal: + db[np.eye(db.shape[0]).astype(bool)] = 0 + ob[np.eye(ob.shape[0]).astype(bool)] = int(params['ABINS']/2) + tb[np.eye(tb.shape[0]).astype(bool)] = int(params['ABINS']/2) + pb[np.eye(pb.shape[0]).astype(bool)] = 0 + + # (11/20/2021) + # Added masking of this diagonal as well. + # This matches the way contact predictions were trained. + d[np.eye(db.shape[0]).astype(bool)] = 0 + + # stack all coords together + if no_angles: + c6d = db[None, :] # only distogram, unsqueezed(0) + else: + c6d = np.stack([db,ob,tb,pb], axis=0) + + # slice long chains + L = idx.shape[0] + start,stop,nres = 0,L,L + sel = np.arange(0, L) + if L > params['LMAX']: + + if params['SLICE'] == 'CONT': + # slice continuously + nres = np.random.randint(params['LMIN'], params['LMAX']) + logger.warning("Slicing long chain %s into %s residues", pdb_path, nres) +# nres = params['LMAX'] + start = np.random.randint(L-nres+1) +# start = 0 + stop = start + nres + sel = np.arange(start,stop) + + if (idx[sel][1:]-idx[sel][:-1]==1).all(): #check if idx has no gaps + feed_dict = { + "idx" : idx[sel], + "idx_raw" : idx, + "coords6d" : c6d[:,sel,:][:,:,sel], + "sel" : sel, + "dist" : d[sel,:][:,sel], + "fullseq" : [seq[0]], + 'no_angles': no_angles, + 'xyz' : orig_xyz + } + else: + feed_dict = { + "idx" : idx[sel], + "idx_raw" : idx, + "coords6d" : np.zeros(1), + "sel" : sel, + "dist" : d[sel,:][:,sel], + "fullseq" : [seq[0]], + 'no_angles': no_angles, + 'xyz' : orig_xyz + } + return feed_dict diff --git a/esm/source/examples/lm-design/utils/sampling.py b/esm/source/examples/lm-design/utils/sampling.py new file mode 100644 index 0000000000000000000000000000000000000000..0eecb7122ead0b3eac1c24bbd865b46b835325b3 --- /dev/null +++ b/esm/source/examples/lm-design/utils/sampling.py @@ -0,0 +1,201 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from contextlib import contextmanager +import logging +import numpy as np +import random +from typing import Any, List, Optional, Union, Dict + +import torch +import torch.nn.functional as F + +from .tensor import ( + assert_logprobs, + is_1hot_tensor, +) + +logger = logging.getLogger(__name__) + +""" +Mental model: + 1. This file contains everything that enables + modifies sampling from distributions. +""" + +SeedDict = Dict[str, Any] +def get_rng_states() -> SeedDict: + """ Retrieves a dictionary of seeds for all rngs. """ + rng_states = { + 'torch': torch.get_rng_state(), + 'torch.cuda': torch.cuda.get_rng_state(), + 'random': random.getstate(), + 'numpy': np.random.get_state(), + } + return rng_states + + +def set_rng_states(rng_state: SeedDict): + """ Sets seeds of all rngs based on a dictionary of rng states. """ + torch.set_rng_state(rng_state['torch']) + torch.cuda.set_rng_state(rng_state['torch.cuda']) + random.setstate(rng_state['random']) + np.random.set_state(rng_state['numpy']) + + +def set_rng_seeds(seed: Union[SeedDict, int]): + """ Sets seeds of all rngs based on a single integer """ + torch.manual_seed(seed) + torch.cuda.manual_seed(seed) + random.seed(seed) + np.random.seed(seed) + + +@contextmanager +def set_rng_seeds_context(seeds: Union[SeedDict, int], disable=False): + """ Context manager for temporarily setting seeds. + For example, can be used when random sampling to get + deterministic outputs for test cases. """ + if disable: + yield + else: + rng_states = get_rng_states() + set_rng_seeds(seeds) + yield + set_rng_states(rng_states) + + +def top_p_filtering(logits, top_p=0.0, filter_value=-float('Inf')): + """ + Filter a distribution of logits using nucleus (top-p) filtering + Args: + logits: prob distribution shape (vocabulary size) + top_p >0.0: keep the top tokens with cumulative probability >= top_p (nucleus filtering). + Nucleus filtering is described in Holtzman et al. (http://arxiv.org/abs/1904.09751) + Returns: + given logits with filter_value at low probabilities (not in top-p) + """ + sorted_logits, sorted_indices = torch.sort(logits, dim=-1, descending=True) + cumulative_probs = torch.cumsum(F.softmax(sorted_logits, dim=-1), dim=-1) + assert (cumulative_probs[..., -1].round() == 1).all(), "Probabilities don't add up to one" + + # Remove tokens with cumulative probability above the threshold + sorted_indices_to_remove = cumulative_probs > top_p + # Shift the indices to the right to keep also the first token above the threshold + sorted_indices_to_remove[..., 1:] = sorted_indices_to_remove[..., :-1].clone() + sorted_indices_to_remove[..., 0] = False + # Reorder the mask to locations before sorting and apply it to logits + sorted_indices_to_remove = sorted_indices_to_remove.gather(-1, sorted_indices.argsort(-1)) + logits[sorted_indices_to_remove] = filter_value + return logits + + +def explore_ratio(probs, x_old, exploration_ratio): + """ + Description: + Given: + 1. a tensor with arbitrary leading dimensions + and valid probabilities in the final dimension + 2. a tensor of same size, but 1-hot in the trailing dimension + apply "eps-force" to all of the distributions. + "eps-force" is a heuristic used in 2021 to prevent self-mutations. + It does two things: + 1. It bounds the probability of positions in `probs` that + are ==1 in `x_old` to be at most == `exploration_ratio`. + 2. If this caused a reduction in probability mass, redistribute + that reduction (`overage`) among the other positions via + __scaling__ the other positions multiplicatively. + This retains the proportionality of the other positions. + Args: + probs (torch.float32): [*, K] + x_old: 1 hot of previous values, to cap. [*, K] + Example: + Given: + probs: [0.8, 0.15, 0.05] + x_old: [1, 0, 0] + exploration_ratio = 0.6 + Return: + [0.8-0.2, 0.15*2, 0.05*2] == [0.6, 0.3, 0.1] + """ + assert probs.shape == x_old.shape, (probs.shape, x_old.shape) + assert is_1hot_tensor(x_old) + thresh = 1 - exploration_ratio + + # Amount that x_old exceeded thresh, in all batch dims. + overage = ((probs * x_old).sum(-1, keepdim=True) - thresh).clamp(0) # [*] + + # Push down old positions accoring to overage. + probs = probs - x_old * overage # [*, K] + + # Scale up all other positions (probs_fresh) so that it sums to overage. + probs_fresh = probs * (1-x_old) + 1e-8 # [*, K] + probs = probs + probs_fresh * overage / probs_fresh.sum(-1, keepdim=True) # [*, K] + + return probs + + +def modify_logits( + # Input: + logits, + + # Settings: + x_old = None, + mask = None, + force_propose_new_tokens = None, + nucleus_sampling_rate = None, + epsilon_force_mutation_ratio = None, + epsilon_greedy_bypass = None, + temperature = None, +): + """ + General purpose modifier of logits/logprobs. + Args: + logits: [*, K] (potentially batched) tensor of distributions in final dim, K. + x_old: [*, K] optional one-hot tensor representing current values. + Some subsequent flags use this to promote sampling of new values. + mask: [K] Boolean tensor for final dimension. + Probability mass is only allowed where mask == True. + force_propose_new_tokens (bool): If true, don't allow any probability mass on returns logprobs where x_old == True. + nucleus_sampling_rate (float in range [0, 1]): Fraction of nucleus sampling to use. + epsilon_force_mutation_ratio (float in range [0, 1]): Fraction of eps-force to use. + epsilon_greedy_bypass (float in range [0, 1]): Fraction of epsilon greedy to use. + temperature (float): The temperature used for conversion of logits -> probs in Softmax operation. + + Returns: + logprobs [*, K]. This is good for numerical precision issues, and is a bit nicer than logits. + """ + # Ensure logprobs at the start + logprobs = logits.log_softmax(-1) + assert_logprobs(logprobs) + K = logprobs.size(-1) + if x_old is not None: + assert logprobs.shape == x_old.shape + + # Handle optional specification of mask, which will clear some positions. + if mask is None: + mask = torch.ones(K, device=logprobs.device).bool() + logits = logprobs.masked_fill(~mask, -float('inf')) + + # Do logprob-based modifications. + if force_propose_new_tokens: + logits = logits.masked_fill(x_old.bool(), -float('inf')) + if nucleus_sampling_rate is not None: + logits = top_p_filtering(logits=logits, top_p=nucleus_sampling_rate) + + # Convert to probs for prob-based modifications. + probs = F.softmax(logits/temperature, dim=-1) + + # Do prob-based modifications. + if epsilon_force_mutation_ratio is not None: + probs = explore_ratio(probs, x_old, epsilon_force_mutation_ratio) + if epsilon_greedy_bypass is not None and torch.rand(1) < epsilon_greedy_bypass: # do only for valid AA's? + probs = torch.ones_like(probs) / K + + # 4. probs -> logits + # NOTE: This eps used to be way too high. + # Keep in mind that eps needs to be lower than 1e-32 for proper test case matching + # in some cases, when adding the global EPS. + log_probs = (probs + 1e-100).log() + logits = log_probs.masked_fill(~mask, -float('inf')) + return logits \ No newline at end of file diff --git a/esm/source/examples/lm-design/utils/scheduler.py b/esm/source/examples/lm-design/utils/scheduler.py new file mode 100644 index 0000000000000000000000000000000000000000..a8153341d21cba6f47e0029bc24aed873faebfc5 --- /dev/null +++ b/esm/source/examples/lm-design/utils/scheduler.py @@ -0,0 +1,69 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from typing import Any, Optional, Union +from numbers import Number + +import torch + +SCHEDULER_REPOSITORY = {} + +class Scheduler: + def __init__( + self, optimizer: Optional[Any], scheduler: str, initial: float, **schedulerspec + ): + if optimizer is None: + # Dummy optimizer to wrap with lr_scheduler + dummy = torch.tensor([], requires_grad=True) + optimizer = torch.optim.SGD([dummy], lr=initial) + self.dummy_optimizer = optimizer + else: + self.dummy_optimizer = None + self.name = scheduler + self._scheduler = getattr(torch.optim.lr_scheduler, self.name)( + optimizer, **schedulerspec + ) + self.initial = initial + + def step(self): + if self.dummy_optimizer: + self.dummy_optimizer.step() # Avoid UserWarning about step order + self._scheduler.step() + + def __call__(self): + return self._scheduler.get_last_lr()[0] + +SchedulerSpecDict = dict +SchedulerSpec = Union[float, str, SchedulerSpecDict] + +class ConstantSchedule(): + """ + Schedule that returns a constant value, defined at init. + Pickle-able, as opposed to `lambda: value`. + """ + def __init__(self, value: Number): + self.value = value + def __call__(self): + return self.value + +def to_scheduler(sspec: SchedulerSpec): + """ Helper for initializing schedulers from config. """ + if isinstance(sspec, str): + sspec = SCHEDULER_REPOSITORY[sspec] + optimizer = None + elif isinstance(sspec, tuple): + # There is an actual optimizer to wrap + optimizer, sspec = sspec + else: + optimizer = None + # Initialize real Scheduler, or dummy lambda + if isinstance(sspec, Number): + return ConstantSchedule(sspec) + else: + return Scheduler(optimizer, **sspec) + +def set_scheduler_repo(repo: dict): + global SCHEDULER_REPOSITORY + SCHEDULER_REPOSITORY = repo diff --git a/esm/source/examples/lm-design/utils/struct_models.py b/esm/source/examples/lm-design/utils/struct_models.py new file mode 100644 index 0000000000000000000000000000000000000000..774591917803ae36f11b2f6338e8542f20c80a79 --- /dev/null +++ b/esm/source/examples/lm-design/utils/struct_models.py @@ -0,0 +1,128 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import logging +from typing import Tuple, Dict +import torch +from torch import nn +from esm.data import Alphabet +from utils.tensor import add_eos_bos, is_1hot_tensor +from torch import nn +from torch.nn import functional as F +from abc import ABC, abstractmethod +import hydra +import os + +from utils.linear_projection import LinearProjectionDistogramModel + +logger = logging.getLogger(__name__) # Hydra configured + +PDB_LOADER_PARAM_REGISTRY = { + 'LinearProjectionDist-1A': { + "DMIN": 2.5, + "DMAX": 20.0, + "DBINS": 17, + "ABINS": 17, + "PHI_BINS": 7, + "WMIN": 0.8, + "LMIN": 150, + "LMAX": 400, + "EPOCHS": 10, + "NCPU": 8, + "SLICE": "CONT", + "contact_bin_cutoff": (0, 5) # both inclusive + }, +} + + +class WrapStruct(nn.Module, ABC): + """ + Wraps structure models used by Designer. + Companion of WrapLM. + """ + def __init__(self, model, vocab, has_eos=False): + super().__init__() + self.model = model + self.vocab = vocab + self.has_eos = has_eos + + @abstractmethod + def forward(self, seq1h, pos_idx=None): + raise NotImplementedError + + @property + def msa_based(self): + return False + + +def load(vocab: Alphabet) -> Tuple[nn.Module, Dict]: + + pdb_loader_params = PDB_LOADER_PARAM_REGISTRY['LinearProjectionDist-1A'] + model = load_model() + has_eos = True + return WrapStructModel(model, vocab, has_eos), pdb_loader_params + + +def load_model(): + model_url_path = 'https://dl.fbaipublicfiles.com/fair-esm/examples/lm_design/linear_projection_model.pt' + local_model_path = hydra.utils.to_absolute_path('./linear_projection_model.pt') + if not os.path.exists(local_model_path): + logger.info(f'Downloading linear projection model from {model_url_path} to {local_model_path}') + os.system(f'wget {model_url_path} -O {local_model_path}') + + # load model_path + state = torch.load(local_model_path, map_location='cpu') + # chkpt_args = state['cfg'] + model = LinearProjectionDistogramModel() + model_state = state['model'] + model.load_state_dict(model_state) + from esm.pretrained import esm2_t33_650M_UR50D + base_model, alphabet = esm2_t33_650M_UR50D() + model.base_model = base_model + return model + + +class WrapStructModel(WrapStruct): + def forward(self, seq1h, pos_idx=None): + assert is_1hot_tensor(seq1h) + B, L, K = seq1h.shape + # Prepend bos/cls only. + eos_idx = self.vocab.eos_idx if self.has_eos else None + seq1h = add_eos_bos(seq1h, bos_idx=self.vocab.cls_idx, eos_idx=eos_idx) + # In designer, all seqs have same length. + src_lengths = torch.full((B,), L + 1 + int(self.has_eos)).to(seq1h).long() + + # In some cases, a vocab padded to 64 positions + # with dummy character was used. + # As a workaround, pad K dimensions up to 64 (embed_dim), + # then remove this portion after to get K tokens back. + embed_dim = self.model.base_model.embed_tokens.weight.size(0) + if embed_dim != K: + seq1h = torch.cat([ + seq1h, + torch.zeros(B, L+1, embed_dim - K).to(seq1h) + ], -1) + + # Call forward. bos/eos will be stripped inside. + out_dict = self.model(seq1h, src_lengths=src_lengths) + return self._process_output(out_dict) + + @property + def lm(self): + return self.model.base_model + + + @staticmethod + def _process_output(out_dict): + for k in ('logits', 'theta_logits', 'phi_logits', 'omega_logits'): + out_dict[k] = out_dict[k].permute(0, 2, 3, 1).contiguous() + + if 'logits' in out_dict: + out_dict['dist_logits'] = out_dict['logits'] + del out_dict['logits'] + for k in [k for k in out_dict if k.endswith('_logits')]: + targetname = k[:-len('_logits')] + out_dict[f'p_{targetname}'] = F.softmax(out_dict[k], -1) + return out_dict diff --git a/esm/source/examples/lm-design/utils/tensor.py b/esm/source/examples/lm-design/utils/tensor.py new file mode 100644 index 0000000000000000000000000000000000000000..7fd9faa2f2ef75d5b5f5a9b610987af0614dd0a4 --- /dev/null +++ b/esm/source/examples/lm-design/utils/tensor.py @@ -0,0 +1,81 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from typing import List, Optional + +import torch +import torch.nn.functional as F + + +def get_line_info(): + from inspect import getframeinfo, currentframe + + caller = getframeinfo(currentframe().f_back) + return f"{caller.filename}:{caller.lineno}" + + +def assert_shape(tensor, *shape_args): + # This only returns the unbound shapes + source = f'{get_line_info()}:' + assert len(tensor.shape) == len(shape_args), f"{source} should have {len(shape_args)} dimensions, actually has shape {tensor.shape}" + unbound = [] + for i, ii in enumerate(shape_args): + if ii == -1: + unbound.append(tensor.shape[i]) + else: + assert ( + tensor.shape[i] == ii + ), f"{source} shape should be {shape_args}, actually {tensor.shape}" + if len(unbound) == 1: + return unbound[0] + return unbound + + +def assert_probs(tensor: torch.FloatTensor): + """ Assert that [*,K] input tensor is valid probs in final dim. """ + assert is_prob_tensor(tensor) + + +def assert_logprobs(tensor: torch.FloatTensor): + """ Assert that [*,K] input tensor is valid logprobs in final dim. """ + try: + assert_probs(tensor.exp()) + except AssertionError: + raise AssertionError('Not logprobs, perhaps you have logits and need to apply F.log_softmax?') + + +def is_1hot_tensor(x1h): + return x1h.min() == 0 and x1h.max() == 1 and \ + x1h.shape[-1] > 1 and (x1h.sum(-1) == 1).all() + + +def is_prob_tensor(p, atol=1e-3): + return ( + p.min() >= 0 + and p.max() <= 1 + and torch.isclose( + p.sum(axis=-1), torch.ones_like(p.sum(axis=-1)), atol=atol).all() + ).item() + + +def add_eos_bos( + seq1h, + bos_idx: Optional[int] = None, + eos_idx: Optional[int] = None, +): + """ + Helper for (possibly) prepending bos/cls and appending eos tokens. + """ + B, L, K = seq1h.shape + + to_concat = [] + if bos_idx is not None: + to_concat.append(F.one_hot(torch.full([B,1], bos_idx), K).to(seq1h)) + to_concat.append(seq1h) + if eos_idx is not None: + to_concat.append(F.one_hot(torch.full([B,1], eos_idx), K).to(seq1h)) + seq1h = torch.cat(to_concat, axis=1) + + return seq1h diff --git a/esm/source/examples/protein-programming-language/README.md b/esm/source/examples/protein-programming-language/README.md new file mode 100644 index 0000000000000000000000000000000000000000..1af1dd9f521b16f16cb1ed2f1221ce07857b98d9 --- /dev/null +++ b/esm/source/examples/protein-programming-language/README.md @@ -0,0 +1,25 @@ +# Protein programming language + +This repository contains an implementation of the programming language described in the paper [A high-level programming language for generative protein design](https://www.biorxiv.org/content/10.1101/2022.12.21.521526v1). + +## Tutorial + +We have provided a [tutorial notebook](tutorial.ipynb) describing the basics of writing programs and running optimization loops. +The notebook can be run in Colab: + +[](https://colab.research.google.com/github/facebookresearch/esm/blob/main/examples/protein-programming-language/tutorial.ipynb) + +## Design programs + +We have also provided some example programs as described in our original paper. + +| Design task | Figure in paper | Program file | +|:--------------------------------------------|:----------------|:----------------------------------------------------------------------------| +| Free hallucination | Figure 2A | [free_hallucination.py](programs/free_hallucination.py) | +| Fixed backbone design | Figure 2D | [fixed_backbone.py](programs/fixed_backbone.py) | +| Secondary structure design | Figure 2G | [secondary_structure.py](programs/secondary_structure.py) | +| Functional site scaffolding | Figure 2H | [functional_site_scaffolding.py](programs/functional_site_scaffolding.py) | +| Symmetric monomer design | Figure 3A | [symmetric_monomer.py](programs/symmetric_monomer.py) | +| Two-level symmetric
homo-oligomer design | Figure 4A | [symmetric_two_level_multimer.py](programs/symmetric_two_level_multimer.py) | +| Symmetric binding site
scaffolding | Figure 5A | [symmetric_binding.py](programs/symmetric_binding.py) | + diff --git a/esm/source/examples/protein-programming-language/language/__init__.py b/esm/source/examples/protein-programming-language/language/__init__.py new file mode 100644 index 0000000000000000000000000000000000000000..2aeb64a98e3ec575d1d06a71bd71bed042d11282 --- /dev/null +++ b/esm/source/examples/protein-programming-language/language/__init__.py @@ -0,0 +1,22 @@ +from language.energy import ( + MaximizeGlobularity, + MaximizePLDDT, + MaximizePTM, + MaximizeSurfaceExposure, + MinimizeCRmsd, + MinimizeDRmsd, + MatchSecondaryStructure, + MinimizeSurfaceExposure, + MinimizeSurfaceHydrophobics, + SymmetryRing, +) +from language.folding_callbacks import EsmFoldv1, FoldingCallback, FoldingResult +from language.optimize import run_simulated_annealing +from language.program import ProgramNode +from language.sequence import ( + ConstantSequenceSegment, + FixedLengthSequenceSegment, + VariableLengthSequenceSegment, + sequence_from_atomarray, +) +from language.utilities import get_atomarray_in_residue_range, pdb_file_to_atomarray diff --git a/esm/source/examples/protein-programming-language/language/energy.py b/esm/source/examples/protein-programming-language/language/energy.py new file mode 100644 index 0000000000000000000000000000000000000000..6ac26d91b13990a41be2f69b0bb1cb18c5b79967 --- /dev/null +++ b/esm/source/examples/protein-programming-language/language/energy.py @@ -0,0 +1,317 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from abc import ABC, abstractmethod +from typing import List, Optional + +import numpy as np +from biotite.structure import annotate_sse, AtomArray, rmsd, sasa, superimpose + +from language.folding_callbacks import FoldingResult +from language.utilities import get_atomarray_in_residue_range + + +class EnergyTerm(ABC): + def __init__(self) -> None: + pass + + @abstractmethod + def compute(self, node, folding_result: FoldingResult) -> float: + pass + + +class MaximizePTM(EnergyTerm): + def __init__(self) -> None: + super().__init__() + + def compute(self, node, folding_result: FoldingResult) -> float: + del node + return 1.0 - folding_result.ptm + + +class MaximizePLDDT(EnergyTerm): + def __init__(self) -> None: + super().__init__() + + def compute(self, node, folding_result: FoldingResult) -> float: + del node + return 1.0 - folding_result.plddt + + +class SymmetryRing(EnergyTerm): + def __init__(self, all_to_all_protomer_symmetry: bool = False) -> None: + super().__init__() + self.all_to_all_protomer_symmetry: bool = all_to_all_protomer_symmetry + + def compute(self, node, folding_result: FoldingResult) -> float: + protomer_nodes = node.get_children() + protomer_residue_ranges = [ + protomer_node.get_residue_index_range() for protomer_node in protomer_nodes + ] + + centers_of_mass = [] + for start, end in protomer_residue_ranges: + backbone_coordinates = get_backbone_atoms( + folding_result.atoms[ + np.logical_and( + folding_result.atoms.res_id >= start, + folding_result.atoms.res_id < end, + ) + ] + ).coord + centers_of_mass.append(get_center_of_mass(backbone_coordinates)) + centers_of_mass = np.vstack(centers_of_mass) + + return ( + float(np.std(pairwise_distances(centers_of_mass))) + if self.all_to_all_protomer_symmetry + else float(np.std(adjacent_distances(centers_of_mass))) + ) + + +def get_backbone_atoms(atoms: AtomArray) -> AtomArray: + return atoms[ + (atoms.atom_name == "CA") | (atoms.atom_name == "N") | (atoms.atom_name == "C") + ] + + +def _is_Nx3(array: np.ndarray) -> bool: + return len(array.shape) == 2 and array.shape[1] == 3 + + +def get_center_of_mass(coordinates: np.ndarray) -> np.ndarray: + assert _is_Nx3(coordinates), "Coordinates must be Nx3." + return coordinates.mean(axis=0).reshape(1, 3) + + +def pairwise_distances(coordinates: np.ndarray) -> np.ndarray: + assert _is_Nx3(coordinates), "Coordinates must be Nx3." + m = coordinates[:, np.newaxis, :] - coordinates[np.newaxis, :, :] + distance_matrix = np.linalg.norm(m, axis=-1) + return distance_matrix[np.triu_indices(distance_matrix.shape[0], k=1)] + + +def adjacent_distances(coordinates: np.ndarray) -> np.ndarray: + assert _is_Nx3(coordinates), "Coordinates must be Nx3." + m = coordinates - np.roll(coordinates, shift=1, axis=0) + return np.linalg.norm(m, axis=-1) + + +class MinimizeSurfaceHydrophobics(EnergyTerm): + def __init__(self) -> None: + super().__init__() + + def compute(self, node, folding_result: FoldingResult) -> float: + start, end = node.get_residue_index_range() + + return hydrophobic_score(folding_result.atoms, start, end) + + +_HYDROPHOBICS = {"VAL", "ILE", "LEU", "PHE", "MET", "TRP"} + + +def hydrophobic_score( + atom_array: AtomArray, + start_residue_index: Optional[int] = None, + end_residue_index: Optional[int] = None, +) -> float: + """ + Computes ratio of hydrophobic atoms in a biotite AtomArray that are also surface + exposed. Typically, lower is better. + """ + + hydrophobic_mask = np.array([aa in _HYDROPHOBICS for aa in atom_array.res_name]) + + if start_residue_index is None and end_residue_index is None: + selection_mask = np.ones_like(hydrophobic_mask) + else: + start_residue_index = 0 if start_residue_index is None else start_residue_index + end_residue_index = ( + len(hydrophobic_mask) if end_residue_index is None else end_residue_index + ) + selection_mask = np.array( + [ + i >= start_residue_index and i < end_residue_index + for i in range(len(hydrophobic_mask)) + ] + ) + + # TODO(scandido): Resolve the float/bool thing going on here. + hydrophobic_surf = np.logical_and( + selection_mask * hydrophobic_mask, sasa(atom_array) + ) + # TODO(brianhie): Figure out how to handle divide-by-zero. + return sum(hydrophobic_surf) / sum(selection_mask * hydrophobic_mask) + + +class MinimizeSurfaceExposure(EnergyTerm): + def __init__(self) -> None: + super().__init__() + + def compute(self, node, folding_result: FoldingResult) -> float: + start, end = node.get_residue_index_range() + + return surface_ratio(folding_result.atoms, list(range(start, end))) + + +class MaximizeSurfaceExposure(EnergyTerm): + def __init__(self) -> None: + super().__init__() + + def compute(self, node, folding_result: FoldingResult) -> float: + start, end = node.get_residue_index_range() + + return 1.0 - surface_ratio(folding_result.atoms, list(range(start, end))) + + +def surface_ratio(atom_array: AtomArray, residue_indices: List[int]) -> float: + """Computes ratio of atoms in specified ratios which are on the protein surface.""" + + residue_mask = np.array([res_id in residue_indices for res_id in atom_array.res_id]) + surface = np.logical_and(residue_mask, sasa(atom_array)) + return sum(surface) / sum(residue_mask) + + +class MinimizeSurfaceExposure(EnergyTerm): + def __init__(self) -> None: + super().__init__() + + def compute(self, node, folding_result: FoldingResult) -> float: + start, end = node.get_residue_index_range() + + return surface_ratio(folding_result.atoms, list(range(start, end))) + + +class MaximizeSurfaceExposure(EnergyTerm): + def __init__(self) -> None: + super().__init__() + + def compute(self, node, folding_result: FoldingResult) -> float: + start, end = node.get_residue_index_range() + + return 1.0 - surface_ratio(folding_result.atoms, list(range(start, end))) + + +def surface_ratio(atom_array: AtomArray, residue_indices: List[int]) -> float: + """Computes ratio of atoms in specified ratios which are on the protein surface.""" + + residue_mask = np.array([res_id in residue_indices for res_id in atom_array.res_id]) + surface = np.logical_and(residue_mask, sasa(atom_array)) + return sum(surface) / sum(residue_mask) + + +class MaximizeGlobularity(EnergyTerm): + def __init__(self) -> None: + super().__init__() + + def compute(self, node, folding_result: FoldingResult) -> float: + start, end = node.get_residue_index_range() + + backbone = get_backbone_atoms( + folding_result.atoms[ + np.logical_and( + folding_result.atoms.res_id >= start, + folding_result.atoms.res_id < end, + ) + ] + ).coord + + return float(np.std(distances_to_centroid(backbone))) + + +def distances_to_centroid(coordinates: np.ndarray) -> np.ndarray: + """ + Computes the distances from each of the coordinates to the + centroid of all coordinates. + """ + assert _is_Nx3(coordinates), "Coordinates must be Nx3." + center_of_mass = get_center_of_mass(coordinates) + m = coordinates - center_of_mass + return np.linalg.norm(m, axis=-1) + + +class MinimizeCRmsd(EnergyTerm): + def __init__(self, template: AtomArray, backbone_only: bool = False) -> None: + super().__init__() + + self.template: AtomArray = template + self.backbone_only: bool = backbone_only + if self.backbone_only: + self.template = get_backbone_atoms(template) + + def compute(self, node, folding_result: FoldingResult) -> float: + start, end = node.get_residue_index_range() + + atoms = get_atomarray_in_residue_range(folding_result.atoms, start, end) + + if self.backbone_only: + atoms = get_backbone_atoms(atoms) + + return crmsd(self.template, atoms) + + +def crmsd(atom_array_a: AtomArray, atom_array_b: AtomArray) -> float: + # TODO(scandido): Add this back. + # atom_array_a = canonicalize_within_residue_atom_order(atom_array_a) + # atom_array_b = canonicalize_within_residue_atom_order(atom_array_b) + superimposed_atom_array_b_onto_a, _ = superimpose(atom_array_a, atom_array_b) + return float(rmsd(atom_array_a, superimposed_atom_array_b_onto_a).mean()) + + +class MinimizeDRmsd(EnergyTerm): + def __init__(self, template: AtomArray, backbone_only: bool = False) -> None: + super().__init__() + + self.template: AtomArray = template + self.backbone_only: bool = backbone_only + if self.backbone_only: + self.template = get_backbone_atoms(template) + + def compute(self, node, folding_result: FoldingResult) -> float: + start, end = node.get_residue_index_range() + + atoms = get_atomarray_in_residue_range(folding_result.atoms, start, end) + + if self.backbone_only: + atoms = get_backbone_atoms(atoms) + + return drmsd(self.template, atoms) + + +def drmsd(atom_array_a: AtomArray, atom_array_b: AtomArray) -> float: + # TODO(scandido): Add this back. + # atom_array_a = canonicalize_within_residue_atom_order(atom_array_a) + # atom_array_b = canonicalize_within_residue_atom_order(atom_array_b) + + dp = pairwise_distances(atom_array_a.coord) + dq = pairwise_distances(atom_array_b.coord) + + return float(np.sqrt(((dp - dq) ** 2).mean())) + + +def pairwise_distances(coordinates: np.ndarray) -> np.ndarray: + assert _is_Nx3(coordinates), "Coordinates must be Nx3." + m = coordinates[:, np.newaxis, :] - coordinates[np.newaxis, :, :] + distance_matrix = np.linalg.norm(m, axis=-1) + return distance_matrix[np.triu_indices(distance_matrix.shape[0], k=1)] + + +class MatchSecondaryStructure(EnergyTerm): + def __init__(self, secondary_structure_element: str) -> None: + super().__init__() + self.secondary_structure_element = secondary_structure_element + + def compute(self, node, folding_result: FoldingResult) -> float: + start, end = node.get_residue_index_range() + + subprotein = folding_result.atoms[ + np.logical_and( + folding_result.atoms.res_id >= start, + folding_result.atoms.res_id < end, + ) + ] + sse = annotate_sse(subprotein) + + return np.mean(sse != self.secondary_structure_element) diff --git a/esm/source/examples/protein-programming-language/language/folding_callbacks.py b/esm/source/examples/protein-programming-language/language/folding_callbacks.py new file mode 100644 index 0000000000000000000000000000000000000000..c2d3d951ae0fd40cb4a008c5f80df82b5d521eee --- /dev/null +++ b/esm/source/examples/protein-programming-language/language/folding_callbacks.py @@ -0,0 +1,78 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from abc import ABC, abstractmethod +from dataclasses import dataclass +from io import StringIO +from typing import List + +import esm +import torch +from biotite.structure import AtomArray +import numpy as np +from openfold.np.residue_constants import atom_order +from torch.utils._pytree import tree_map + +from language.utilities import pdb_file_to_atomarray + + +@dataclass +class FoldingResult: + atoms: AtomArray + ptm: float + plddt: float + + +class FoldingCallback(ABC): + "Interface for running ESMFold and other folding methods." + + def __init__(self) -> None: + pass + + @abstractmethod + def load(self, device: str) -> None: + pass + + @abstractmethod + def fold(self, sequence: str, residue_indices: List[int]) -> FoldingResult: + pass + + +class EsmFoldv1(FoldingCallback): + "Runs ESMFold v1.0." + + def __init__(self) -> None: + super().__init__() + + self.model = None + + def load(self, device: str) -> None: + self.model = esm.pretrained.esmfold_v1().eval() + self.model = self.model.to(device) + + def fold(self, sequence: str, residue_indices: List[int]) -> FoldingResult: + assert self.model is not None, "Must call load() before fold()." + + # TODO: Current `esm.esmfold.v1.misc.output_to_pdb()` adds 1 to the `residx` + # mistakenly, just subtract 1 for now but fix in a later version. + residue_indices = np.array(residue_indices) - 1 + + raw_output = self.model.infer( + sequence, residx=torch.Tensor(residue_indices).long().reshape(1, -1), + ) + raw_output = tree_map(lambda x: x.to("cpu"), raw_output) + + pdb_string = esm.esmfold.v1.misc.output_to_pdb(raw_output)[0] + atoms: AtomArray = pdb_file_to_atomarray(StringIO(pdb_string)) + + plddt = raw_output["plddt"] + plddt = plddt[0, ...].numpy() + plddt = plddt.transpose() + plddt = plddt[atom_order["CA"], :] + plddt = float(plddt.mean()) / 100.0 + + ptm = float(raw_output["ptm"]) + + return FoldingResult(atoms=atoms, ptm=ptm, plddt=plddt) diff --git a/esm/source/examples/protein-programming-language/language/optimize.py b/esm/source/examples/protein-programming-language/language/optimize.py new file mode 100644 index 0000000000000000000000000000000000000000..865a49c62fceda832156ac0ce0eab8be0b63e43c --- /dev/null +++ b/esm/source/examples/protein-programming-language/language/optimize.py @@ -0,0 +1,158 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from copy import deepcopy +from dataclasses import dataclass + +import numpy as np +from rich.live import Live +from rich.table import Table + +from language.folding_callbacks import FoldingCallback +from language.program import ProgramNode + + +@dataclass +class MetropolisHastingsState: + program: ProgramNode + temperature: float + annealing_rate: float + num_steps: int + candidate_energy: float + candidate_energy_term_fn_values: list + current_energy: float + current_energy_term_fn_values: list + best_energy: float + best_energy_term_fn_values: list + + +def metropolis_hastings_step( + state: MetropolisHastingsState, + folding_callback: FoldingCallback, + verbose: bool = False, +) -> MetropolisHastingsState: + temperature = state.temperature * state.annealing_rate + + candidate: ProgramNode = deepcopy(state.program) + candidate.mutate() + + sequence, residue_indices = candidate.get_sequence_and_set_residue_index_ranges() + folding_output = folding_callback.fold(sequence, residue_indices) + + energy_term_fns = candidate.get_energy_term_functions() + candidate_energy_term_fn_values = [ + (name, weight, energy_fn(folding_output)) for name, weight, energy_fn in energy_term_fns + ] + # TODO(scandido): Log these. + candidate_energy: float = sum( + [weight * value for _, weight, value in candidate_energy_term_fn_values] + ) + + accept_candidate = False + if state.current_energy is None: + accept_candidate = True + else: + # NOTE(scandido): We are minimizing the function here so instead of + # candidate - current we do -1 * (candidate - current) = -candidate + current. + energy_differential: float = -candidate_energy + state.current_energy + accept_probability: float = np.clip( + # NOTE(scandido): We approximate the ratio of transition probabilities from + # current to candidate vs. candidate to current to be equal, which is + # approximately correct. + np.exp(energy_differential / temperature), + a_min=None, + a_max=1.0, + ) + accept_candidate: bool = np.random.uniform() < accept_probability + + if accept_candidate and verbose: + print(f"Accepted {sequence} with energy {candidate_energy:.2f}.") + + best = (state.best_energy is None) or candidate_energy < state.best_energy + + return MetropolisHastingsState( + program=candidate if accept_candidate else state.program, + temperature=temperature, + annealing_rate=state.annealing_rate, + num_steps=state.num_steps + 1, + candidate_energy=candidate_energy, + candidate_energy_term_fn_values=candidate_energy_term_fn_values, + current_energy=candidate_energy if accept_candidate else state.current_energy, + current_energy_term_fn_values=candidate_energy_term_fn_values + if accept_candidate + else state.current_energy_term_fn_values, + best_energy=candidate_energy if best else state.best_energy, + best_energy_term_fn_values=candidate_energy_term_fn_values + if best + else state.best_energy_term_fn_values, + ) + + +def run_simulated_annealing( + program: ProgramNode, + initial_temperature: float, + annealing_rate: float, + total_num_steps: int, + folding_callback: FoldingCallback, + display_progress: bool = True, + progress_verbose_print: bool = False, +) -> ProgramNode: + # TODO(scandido): Track accept rate. + + state = MetropolisHastingsState( + program=program, + temperature=initial_temperature, + annealing_rate=annealing_rate, + num_steps=0, + candidate_energy=None, + candidate_energy_term_fn_values=None, + current_energy=None, + current_energy_term_fn_values=None, + best_energy=None, + best_energy_term_fn_values=None, + ) + + def _generate_table(state): + table = Table() + table.add_column("Energy name") + table.add_column("Weight") + table.add_column("Candidate Value") + table.add_column("Current Value") + table.add_column("Best Value") + if state.current_energy_term_fn_values is None: + return table + for (name, weight, candidate_value), (_, _, current_value), (_, _, best_value) in zip( + state.candidate_energy_term_fn_values, + state.current_energy_term_fn_values, + state.best_energy_term_fn_values, + ): + table.add_row( + name, + f"{weight:.2f}", + f"{candidate_value:.2f}", + f"{current_value:.2f}", + f"{best_value:.2f}", + ) + table.add_row( + "Energy", + "", + f"{state.candidate_energy:.2f}", + f"{state.current_energy:.2f}", + f"{state.best_energy:.2f}", + ) + table.add_row("Iterations", "", f"{state.num_steps} / {total_num_steps}") + return table + + with Live() as live: + for _ in range(1, total_num_steps + 1): + state = metropolis_hastings_step( + state, + folding_callback, + verbose=progress_verbose_print, + ) + if display_progress: + live.update(_generate_table(state)) + + return state.program diff --git a/esm/source/examples/protein-programming-language/language/program.py b/esm/source/examples/protein-programming-language/language/program.py new file mode 100644 index 0000000000000000000000000000000000000000..57e4f72af7bee26ea6ad29df38c2cbb947f9d78f --- /dev/null +++ b/esm/source/examples/protein-programming-language/language/program.py @@ -0,0 +1,127 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from functools import partial +from typing import Callable, List, Optional, Tuple + +import numpy as np + +from language.energy import EnergyTerm +from language.folding_callbacks import FoldingResult +from language.sequence import SequenceSegmentFactory + +MULTIMER_RESIDUE_INDEX_SKIP_LENGTH: int = 1000 + + +class ProgramNode: + def __init__( + self, + children: List["ProgramNode"] = None, + sequence_segment: SequenceSegmentFactory = None, + children_are_different_chains: bool = False, + energy_function_terms: List[EnergyTerm] = [], + energy_function_weights: Optional[List[float]] = None, + ) -> None: + self.children: Optional[List["ProgramNode"]] = children + self.sequence_segment: SequenceSegmentFactory = sequence_segment + self.children_are_different_chains: bool = children_are_different_chains + self.energy_function_terms: List[energy_function_terms] = energy_function_terms + self.energy_function_weights: List[ + float + ] = energy_function_weights if energy_function_weights else [ + 1.0 for _ in self.energy_function_terms + ] + if self.energy_function_weights: + assert len(self.energy_function_terms) == len( + self.energy_function_weights + ), "One must have the same number of energy function terms and weights on a node." + + self.residue_index_range: Optional[Tuple[int, int]] = None + + def get_sequence_and_set_residue_index_ranges( + self, residue_index_offset: int = 1 + ) -> Tuple[str, List[int]]: + if self.is_leaf_node(): + sequence = self.sequence_segment.get() + self.residue_index_range = ( + residue_index_offset, + residue_index_offset + len(sequence), + ) + return sequence, list(range(*self.residue_index_range)) + + offset: int = residue_index_offset + sequence = "" + residue_indices = [] + for child in self.children: + ( + sequence_segment, + residue_indices_segment, + ) = child.get_sequence_and_set_residue_index_ranges( + residue_index_offset=offset + ) + sequence += sequence_segment + residue_indices += residue_indices_segment + offset = residue_indices[-1] + 1 + if self.children_are_different_chains: + offset += MULTIMER_RESIDUE_INDEX_SKIP_LENGTH + self.residue_index_range = (residue_indices[0], residue_indices[-1] + 1) + return sequence, residue_indices + + def get_residue_index_range(self) -> Tuple[int, int]: + assert ( + self.residue_index_range + ), "Must call get_sequence_and_set_residue_index_ranges() first." + return self.residue_index_range + + def get_children(self) -> List["ProgramNode"]: + return self.children + + def is_leaf_node(self) -> bool: + return self.children is None + + def get_energy_term_functions( + self, name_prefix: str = "" + ) -> List[Tuple[str, float, Callable[[FoldingResult], float]]]: + name_prefix = name_prefix if name_prefix else "root" + + terms = [ + ( + f"{name_prefix}:{type(term).__name__}", + weight, + partial(term.compute, self), + ) + for weight, term in zip( + self.energy_function_weights, self.energy_function_terms + ) + ] + + if self.is_leaf_node(): + return terms + + for i, child in enumerate(self.children): + terms += child.get_energy_term_functions( + name_prefix=name_prefix + f".n{i+1}" + ) + + return terms + + def mutate(self) -> None: + if self.is_leaf_node(): + return self.sequence_segment.mutate() + + weights = np.array( + [float(child.num_mutation_candidates()) for child in self.children] + ) + assert ( + weights.sum() > 0 + ), "Some mutations should be possible if mutate() was called." + child_to_mutate = np.random.choice(self.children, p=weights / weights.sum()) + child_to_mutate.mutate() + + def num_mutation_candidates(self) -> int: + if self.is_leaf_node(): + return self.sequence_segment.num_mutation_candidates() + + return sum([child.num_mutation_candidates() for child in self.children]) diff --git a/esm/source/examples/protein-programming-language/language/sequence.py b/esm/source/examples/protein-programming-language/language/sequence.py new file mode 100644 index 0000000000000000000000000000000000000000..f7bf1969388d7694873d608c8400e56f1e28a332 --- /dev/null +++ b/esm/source/examples/protein-programming-language/language/sequence.py @@ -0,0 +1,221 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from abc import ABC, abstractmethod +from copy import deepcopy +from typing import List, Union + +import numpy as np +from biotite.structure import AtomArray + +ALL_RESIDUE_TYPES = [ + "A", + "R", + "N", + "D", + "C", + "Q", + "E", + "G", + "H", + "I", + "L", + "K", + "M", + "F", + "P", + "S", + "T", + "W", + "Y", + "V", +] + +RESIDUE_TYPES_WITHOUT_CYSTEINE = deepcopy(ALL_RESIDUE_TYPES) +RESIDUE_TYPES_WITHOUT_CYSTEINE.remove("C") + +RESIDUE_TYPES_1to3 = { + "A": "ALA", + "R": "ARG", + "N": "ASN", + "D": "ASP", + "C": "CYS", + "Q": "GLN", + "E": "GLU", + "G": "GLY", + "H": "HIS", + "I": "ILE", + "L": "LEU", + "K": "LYS", + "M": "MET", + "F": "PHE", + "P": "PRO", + "S": "SER", + "T": "THR", + "W": "TRP", + "Y": "TYR", + "V": "VAL", +} +RESIDUE_TYPES_3to1 = {v: k for k, v in RESIDUE_TYPES_1to3.items()} + + +class SequenceSegmentFactory(ABC): + def __init__(self) -> None: + pass + + @abstractmethod + def get(self) -> str: + pass + + @abstractmethod + def mutate(self) -> None: + pass + + @abstractmethod + def num_mutation_candidates(self) -> int: + pass + + +class ConstantSequenceSegment(SequenceSegmentFactory): + def __init__(self, sequence: str) -> None: + super().__init__() + self.sequence = sequence + + def get(self) -> str: + return self.sequence + + def mutate(self) -> None: + pass + + def num_mutation_candidates(self) -> int: + return 0 + + +class FixedLengthSequenceSegment(SequenceSegmentFactory): + def __init__( + self, initial_sequence: Union[str, int], disallow_mutations_to_cysteine=True, + ) -> None: + super().__init__() + self.mutation_residue_types = ( + RESIDUE_TYPES_WITHOUT_CYSTEINE + if disallow_mutations_to_cysteine + else ALL_RESIDUE_TYPES + ) + + self.sequence = ( + initial_sequence + if type(initial_sequence) == str + else random_sequence( + length=initial_sequence, corpus=self.mutation_residue_types + ) + ) + + def get(self) -> str: + return self.sequence + + def mutate(self) -> None: + self.sequence = substitute_one_amino_acid( + self.sequence, self.mutation_residue_types + ) + + def num_mutation_candidates(self) -> int: + return len(self.sequence) + + +def substitute_one_amino_acid(sequence: str, corpus: List[str]) -> str: + sequence = list(sequence) + index = np.random.choice(len(sequence)) + sequence[index] = np.random.choice(corpus) + return "".join(sequence) + + +def random_sequence(length: int, corpus: List[str]) -> str: + "Generate a random sequence using amino acids in corpus." + + return "".join([np.random.choice(corpus) for _ in range(length)]) + + +def sequence_from_atomarray(atoms: AtomArray) -> str: + return "".join( + [RESIDUE_TYPES_3to1[aa] for aa in atoms[atoms.atom_name == "CA"].res_name] + ) + + +class VariableLengthSequenceSegment(SequenceSegmentFactory): + def __init__( + self, + initial_sequence: Union[str, int], + disallow_mutations_to_cysteine=True, + mutation_operation_probabilities: List[float] = [ + 3., # Substitution weight. + 1., # Deletion weight. + 1., # Insertion weight. + ], + ) -> None: + super().__init__() + self.mutation_residue_types = ( + RESIDUE_TYPES_WITHOUT_CYSTEINE + if disallow_mutations_to_cysteine + else ALL_RESIDUE_TYPES + ) + + self.sequence = ( + initial_sequence + if type(initial_sequence) == str + else random_sequence( + length=initial_sequence, corpus=self.mutation_residue_types + ) + ) + + self.mutation_operation_probabilities = np.array(mutation_operation_probabilities) + self.mutation_operation_probabilities /= self.mutation_operation_probabilities.sum() + + def get(self) -> str: + return self.sequence + + def mutate(self) -> None: + mutation_operation = np.random.choice( + [ + self._mutate_substitution, + self._mutate_deletion, + self._mutate_insertion, + ], + p=self.mutation_operation_probabilities, + ) + mutation_operation() + + def _mutate_substitution(self) -> str: + self.sequence = substitute_one_amino_acid( + self.sequence, self.mutation_residue_types + ) + + def _mutate_deletion(self) -> str: + self.sequence = delete_one_amino_acid(self.sequence) + + def _mutate_insertion(self) -> str: + self.sequence = insert_one_amino_acid( + self.sequence, self.mutation_residue_types + ) + + def num_mutation_candidates(self) -> int: + # NOTE(brianhie): This should be `3*len(self.sequence) + 1`, + # since there are `len(self.sequence)` substitutions and + # deletions, and `len(self.sequence) + 1` insertions. + # However, as this is used to weight sequence segments for + # mutations when combined into a multi-segment program, we + # just weight by `len(self.sequence)` for now. + return len(self.sequence) + + +def delete_one_amino_acid(sequence: str) -> str: + index = np.random.choice(len(sequence)) + return sequence[:index] + sequence[index + 1 :] + + +def insert_one_amino_acid(sequence: str, corpus: List[str]) -> str: + n = len(sequence) + index = np.random.randint(0, n) if n > 0 else 0 + insertion = np.random.choice(corpus) + return sequence[:index] + insertion + sequence[index:] diff --git a/esm/source/examples/protein-programming-language/language/utilities.py b/esm/source/examples/protein-programming-language/language/utilities.py new file mode 100644 index 0000000000000000000000000000000000000000..554c791533ceb9b911777c3c20bb68a6dc6b38e1 --- /dev/null +++ b/esm/source/examples/protein-programming-language/language/utilities.py @@ -0,0 +1,19 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from io import StringIO +from typing import Union + +import numpy as np +from biotite.structure import AtomArray +from biotite.structure.io.pdb import PDBFile + + +def pdb_file_to_atomarray(pdb_path: Union[str, StringIO]) -> AtomArray: + return PDBFile.read(pdb_path).get_structure(model=1) + + +def get_atomarray_in_residue_range(atoms: AtomArray, start: int, end: int) -> AtomArray: + return atoms[np.logical_and(atoms.res_id >= start, atoms.res_id < end)] diff --git a/esm/source/examples/protein-programming-language/programs/__init__.py b/esm/source/examples/protein-programming-language/programs/__init__.py new file mode 100644 index 0000000000000000000000000000000000000000..10dbba2011e3b31be63d8042804749f4cb77839a --- /dev/null +++ b/esm/source/examples/protein-programming-language/programs/__init__.py @@ -0,0 +1 @@ +from programs.symmetric_binding import symmetric_binding_il10 diff --git a/esm/source/examples/protein-programming-language/programs/fixed_backbone.py b/esm/source/examples/protein-programming-language/programs/fixed_backbone.py new file mode 100644 index 0000000000000000000000000000000000000000..b074828f6f3c1816342dcf085cdb5517bd086202 --- /dev/null +++ b/esm/source/examples/protein-programming-language/programs/fixed_backbone.py @@ -0,0 +1,39 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from copy import deepcopy + +from biotite.database.rcsb import fetch +from biotite.structure import AtomArray + +from language import ( + FixedLengthSequenceSegment, + MaximizePLDDT, + MaximizePTM, + MinimizeCRmsd, + MinimizeDRmsd, + MinimizeSurfaceHydrophobics, + ProgramNode, + pdb_file_to_atomarray, + sequence_from_atomarray, +) + + +def fixed_backbone_6mrs() -> ProgramNode: + template_atoms: AtomArray = pdb_file_to_atomarray(fetch("6mrs", format="pdb")) + + sequence_length = len(sequence_from_atomarray(template_atoms)) + sequence = FixedLengthSequenceSegment(sequence_length) + + return ProgramNode( + sequence_segment=sequence, + energy_function_terms=[ + MaximizePTM(), + MaximizePLDDT(), + MinimizeSurfaceHydrophobics(), + MinimizeCRmsd(template=template_atoms, backbone_only=True), + MinimizeDRmsd(template=template_atoms, backbone_only=True), + ], + ) diff --git a/esm/source/examples/protein-programming-language/programs/free_hallucination.py b/esm/source/examples/protein-programming-language/programs/free_hallucination.py new file mode 100644 index 0000000000000000000000000000000000000000..12d2802629878447eb87acb0830d0389ecd7c190 --- /dev/null +++ b/esm/source/examples/protein-programming-language/programs/free_hallucination.py @@ -0,0 +1,24 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from language import ( + FixedLengthSequenceSegment, + MaximizePLDDT, + MaximizePTM, + MinimizeSurfaceHydrophobics, + ProgramNode, +) + + +def free_hallucination(sequence_length: int) -> ProgramNode: + sequence = FixedLengthSequenceSegment(sequence_length) + return ProgramNode( + sequence_segment=sequence, + energy_function_terms=[ + MaximizePTM(), + MaximizePLDDT(), + MinimizeSurfaceHydrophobics(), + ], + ) diff --git a/esm/source/examples/protein-programming-language/programs/functional_site_scaffolding.py b/esm/source/examples/protein-programming-language/programs/functional_site_scaffolding.py new file mode 100644 index 0000000000000000000000000000000000000000..7bad2604f24b64d87db20b5a025d5101407e1274 --- /dev/null +++ b/esm/source/examples/protein-programming-language/programs/functional_site_scaffolding.py @@ -0,0 +1,58 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from copy import deepcopy + +from biotite.database.rcsb import fetch +from biotite.structure import AtomArray + +from language import ( + ConstantSequenceSegment, + MaximizePLDDT, + MaximizePTM, + MaximizeSurfaceExposure, + MinimizeCRmsd, + MinimizeDRmsd, + MinimizeSurfaceHydrophobics, + ProgramNode, + VariableLengthSequenceSegment, + get_atomarray_in_residue_range, + pdb_file_to_atomarray, + sequence_from_atomarray, +) + + +def scaffolding_ace2() -> ProgramNode: + binding_site_atoms: AtomArray = pdb_file_to_atomarray(fetch("6m0j", format="pdb")) + binding_site_atoms = get_atomarray_in_residue_range( + binding_site_atoms, start=23, end=42 + ) + binding_site_sequence: str = sequence_from_atomarray(binding_site_atoms) + print(binding_site_sequence) + + leader_amino_acid_sequence = VariableLengthSequenceSegment(50) + binding_site_sequence = ConstantSequenceSegment(binding_site_sequence) + follower_amino_acid_sequence = VariableLengthSequenceSegment(50) + + return ProgramNode( + energy_function_terms=[ + MaximizePTM(), + MaximizePLDDT(), + MinimizeSurfaceHydrophobics(), + ], + children=[ + ProgramNode(sequence_segment=leader_amino_acid_sequence), + ProgramNode( + sequence_segment=binding_site_sequence, + energy_function_terms=[ + MaximizeSurfaceExposure(), + MinimizeCRmsd(template=binding_site_atoms), + MinimizeDRmsd(template=binding_site_atoms), + ], + energy_function_weights=[1.0, 10.0, 10.0], + ), + ProgramNode(sequence_segment=follower_amino_acid_sequence), + ] + ) diff --git a/esm/source/examples/protein-programming-language/programs/secondary_structure.py b/esm/source/examples/protein-programming-language/programs/secondary_structure.py new file mode 100644 index 0000000000000000000000000000000000000000..42a734f0552cccef66bafef57e184adfd1ffedda --- /dev/null +++ b/esm/source/examples/protein-programming-language/programs/secondary_structure.py @@ -0,0 +1,47 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from language import ( + FixedLengthSequenceSegment, + MaximizePLDDT, + MaximizePTM, + MatchSecondaryStructure, + MinimizeSurfaceHydrophobics, + ProgramNode, +) + + +def secondary_structure( + node1_sse: str = 'a', + node2_sse: str = 'b', +) -> ProgramNode: + """ + Free hallucinates a protein while controlling the secondary structure + corresponding to different segments of the sequence. + Specify `'a'` for alpha helix, `'b'` for beta sheet, and `'c'` for coils. + """ + node1 = ProgramNode( + sequence_segment=FixedLengthSequenceSegment(50), + energy_function_terms=[ + MatchSecondaryStructure(node1_sse), + #TODO(brianhie): Add globularity here. + ] + ) + node2 = ProgramNode( + sequence_segment=FixedLengthSequenceSegment(50), + energy_function_terms=[ + MatchSecondaryStructure(node2_sse), + #TODO(brianhie): Add globularity here. + ] + ) + + return ProgramNode( + energy_function_terms=[ + MaximizePTM(), + MaximizePLDDT(), + MinimizeSurfaceHydrophobics(), + ], + children=[node1, node2,], + ) diff --git a/esm/source/examples/protein-programming-language/programs/symmetric_binding.py b/esm/source/examples/protein-programming-language/programs/symmetric_binding.py new file mode 100644 index 0000000000000000000000000000000000000000..fce7a2475e9af5c596f540a365f8f969ef3def69 --- /dev/null +++ b/esm/source/examples/protein-programming-language/programs/symmetric_binding.py @@ -0,0 +1,64 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from copy import deepcopy + +from biotite.database.rcsb import fetch +from biotite.structure import AtomArray + +from language import ( + ConstantSequenceSegment, + FixedLengthSequenceSegment, + MaximizePLDDT, + MaximizePTM, + MaximizeSurfaceExposure, + MinimizeCRmsd, + MinimizeDRmsd, + MinimizeSurfaceHydrophobics, + ProgramNode, + SymmetryRing, + get_atomarray_in_residue_range, + pdb_file_to_atomarray, + sequence_from_atomarray, +) + + +def symmetric_binding_il10(num_binding_sites: int = 3) -> ProgramNode: + binding_site_atoms: AtomArray = pdb_file_to_atomarray(fetch("1y6k", format="pdb")) + binding_site_atoms = get_atomarray_in_residue_range( + binding_site_atoms, start=31, end=40 + ) + binding_site_sequence: str = sequence_from_atomarray(binding_site_atoms) + + leader_amino_acid_sequence = FixedLengthSequenceSegment(45) + binding_site_sequence = ConstantSequenceSegment(binding_site_sequence) + follower_amino_acid_sequence = FixedLengthSequenceSegment(45) + + def _binder_protomer_program() -> ProgramNode: + return ProgramNode( + children=[ + ProgramNode(sequence_segment=leader_amino_acid_sequence), + ProgramNode( + sequence_segment=binding_site_sequence, + energy_function_terms=[ + MaximizeSurfaceExposure(), + MinimizeCRmsd(template=binding_site_atoms), + MinimizeDRmsd(template=binding_site_atoms), + ], + energy_function_weights=[1.0, 10.0, 10.0], + ), + ProgramNode(sequence_segment=follower_amino_acid_sequence), + ] + ) + + return ProgramNode( + energy_function_terms=[ + MaximizePTM(), + MaximizePLDDT(), + SymmetryRing(), + MinimizeSurfaceHydrophobics(), + ], + children=[_binder_protomer_program() for _ in range(num_binding_sites)], + ) diff --git a/esm/source/examples/protein-programming-language/programs/symmetric_monomer.py b/esm/source/examples/protein-programming-language/programs/symmetric_monomer.py new file mode 100644 index 0000000000000000000000000000000000000000..5810b04714f66dcd3f5f3ce4f844287cbb3cb3a9 --- /dev/null +++ b/esm/source/examples/protein-programming-language/programs/symmetric_monomer.py @@ -0,0 +1,36 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from language import ( + FixedLengthSequenceSegment, + MaximizePLDDT, + MaximizePTM, + MinimizeSurfaceHydrophobics, + ProgramNode, + SymmetryRing, +) + + +def symmetric_monomer(num_protomers: int) -> ProgramNode: + protomer_sequence = FixedLengthSequenceSegment(50) + def _make_protomer_node(): + # A new ProgramNode must be made for each new protomer, + # but the sequence can (and should) be shared. + return ProgramNode( + sequence_segment=protomer_sequence + ) + + return ProgramNode( + energy_function_terms=[ + MaximizePTM(), + MaximizePLDDT(), + SymmetryRing(), + MinimizeSurfaceHydrophobics(), + ], + children=[ + _make_protomer_node() + for _ in range(num_protomers) + ], + ) diff --git a/esm/source/examples/protein-programming-language/programs/symmetric_two_level_multimer.py b/esm/source/examples/protein-programming-language/programs/symmetric_two_level_multimer.py new file mode 100644 index 0000000000000000000000000000000000000000..97ff9ecf213984f24020f2077a1267e2f05e7a29 --- /dev/null +++ b/esm/source/examples/protein-programming-language/programs/symmetric_two_level_multimer.py @@ -0,0 +1,65 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from language import ( + FixedLengthSequenceSegment, + MaximizePLDDT, + MaximizePTM, + MinimizeSurfaceHydrophobics, + ProgramNode, + SymmetryRing, + MaximizeGlobularity, +) + + +def symmetric_two_level_multimer( + num_chains: int, + num_protomers_per_chain: int, + protomer_sequence_length: int = 50, +) -> ProgramNode: + """ + Programs a homo-oligomeric protein with two-level symmetry. + The number of chains in the multimer is specified by `num_chains`. + A protomer sequence, with length `protomer_sequence_length`, is + repeated `num_protomers_per_chain` times. + For example, a two-chain protein with three protomers per chain + would repeat the protomer six times. + """ + + # The basic repeated unit. + protomer_sequence = FixedLengthSequenceSegment(protomer_sequence_length) + def _make_protomer_node(): + return ProgramNode(sequence_segment=protomer_sequence) + + # Protomers are symmetrically combined into a chain. + def _make_chain_node(): + return ProgramNode( + energy_function_terms=[ + SymmetryRing(), + MaximizeGlobularity(), + ], + energy_function_weights=[1., 0.05,], + children=[ + _make_protomer_node() + for _ in range(num_protomers_per_chain) + ], + ) + + # Chains are symmetrically combined into a multimer. + return ProgramNode( + energy_function_terms=[ + MaximizePTM(), + MaximizePLDDT(), + SymmetryRing(), + MinimizeSurfaceHydrophobics(), + ], + children=[ + _make_chain_node() + for _ in range(num_chains) + ], + children_are_different_chains=True, + ) + + diff --git a/esm/source/examples/protein-programming-language/tutorial.ipynb b/esm/source/examples/protein-programming-language/tutorial.ipynb new file mode 100644 index 0000000000000000000000000000000000000000..03eda6d76dafb36b06cd8331e92df44216762a89 --- /dev/null +++ b/esm/source/examples/protein-programming-language/tutorial.ipynb @@ -0,0 +1,253 @@ +{ + "cells": [ + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "# High-level protein programming language tutorial\n", + "\n", + "In this notebook, we will walk through creating a simple program encoding a symmetric protein and running an optimization run.\n", + "At the end of the notebook, we will also link to examples of more complex design programs.\n", + "\n", + "We design proteins guided by [ESMFold](https://github.com/facebookresearch/esm#esmfold), so let's get set up by loading the ESMFold model." + ] + }, + { + "cell_type": "code", + "execution_count": 1, + "metadata": {}, + "outputs": [], + "source": [ + "%load_ext autoreload\n", + "%autoreload 2" + ] + }, + { + "cell_type": "code", + "execution_count": 2, + "metadata": {}, + "outputs": [], + "source": [ + "from language import EsmFoldv1\n", + "\n", + "folding_callback = EsmFoldv1()\n", + "folding_callback.load(device=\"cuda:0\")" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "Now let's write a program.\n", + "Our high-level programming language is organized by a *syntax tree*, where *leaf nodes* correspond to protein sequence segments. To begin, let's create a leaf node defined on a fixed-length sequence segment with 25 amino acid residues:" + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "metadata": {}, + "outputs": [], + "source": [ + "from language import FixedLengthSequenceSegment\n", + "from language import ProgramNode\n", + "\n", + "protomer = FixedLengthSequenceSegment(25)\n", + "def make_protomer_node():\n", + " return ProgramNode(sequence_segment=protomer)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "For this tutorial, we will make a symmetric protein by repeating the above protomer sequence $N$ times, where $N$ is the desired rotational symmetry.\n", + "\n", + "Our programming language enables *internal nodes* in the syntax tree that let us hierarchically control multiple child nodes. To program a protein with 3-fold symmetry, let's create an internal node with $N = 3$ children." + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "metadata": {}, + "outputs": [], + "source": [ + "N = 3\n", + "_node = ProgramNode(\n", + " children=[make_protomer_node() for _ in range(N)],\n", + ")" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "To complete our programming language, we require a set of *constraints*.\n", + "An important set of constraints to apply to all proteins is to maximize ESMFold's confidence in the model structure, which we quantify by the pTM and mean pLDDT scores.\n", + "We also want to constrain the protein to have rotational symmetry.\n", + "\n", + "Adding those three constraints (on pTM, pLDDT, and symmetry) completes the simple program for a symmetric protein.\n", + "We can also weight different constraints differently; for this tutorial, we will double the weight on the symmetry constraint.\n", + "The constraints are compiled into a single *energy function* (right now, via a linear combination of constraint functions), which we will use to guide the optimization algorithm\n", + "\n", + "The code below will add the constraints and weights, compile the program, and print out a summary of the energy function." + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "root:MaximizePTM = 1.0 * 0.84\n", + "root:MaximizePLDDT = 1.0 * 0.65\n", + "root:SymmetryRing = 1.0 * 0.57\n" + ] + } + ], + "source": [ + "from language import MaximizePTM, MaximizePLDDT, SymmetryRing\n", + "\n", + "# Define the program.\n", + "program = ProgramNode(\n", + " energy_function_terms=[MaximizePTM(), MaximizePLDDT(), SymmetryRing()],\n", + " energy_function_weights=[1.0, 1.0, 1.0],\n", + " children=[make_protomer_node() for _ in range(N)],\n", + ")\n", + "\n", + "# Set up the program.\n", + "sequence, residue_indices = program.get_sequence_and_set_residue_index_ranges()\n", + "\n", + "# Compute and print the energy function.\n", + "energy_terms = program.get_energy_term_functions()\n", + "folding_output = folding_callback.fold(sequence, residue_indices)\n", + "for name, weight, energy_fn in energy_terms:\n", + " print(f\"{name} = {weight:.1f} * {energy_fn(folding_output):.2f}\")" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "We are now ready to use this program to guide an optimization loop to design a protein sequence and structure.\n", + "We currently perform simulated annealing of an MCMC optimization algorithm to do design.\n", + "The code below will set up the simulated annealing algorithm, including the relevant parameters, and run the optimization loop. " + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "data": { + "application/vnd.jupyter.widget-view+json": { + "model_id": "2883ee40821e4f5ca4f699b96fe837e2", + "version_major": 2, + "version_minor": 0 + }, + "text/plain": [ + "Output()" + ] + }, + "metadata": {}, + "output_type": "display_data" + }, + { + "data": { + "text/html": [ + "
/private/home/brianhie/protein-bert-model/examples/protein-programming-language/language/optimize.py:56: \n",
+       "RuntimeWarning: overflow encountered in exp\n",
+       "  np.exp(energy_differential / temperature),\n",
+       "
\n" + ], + "text/plain": [ + "/private/home/brianhie/protein-bert-model/examples/protein-programming-language/language/optimize.py:56: \n", + "RuntimeWarning: overflow encountered in exp\n", + " np.exp(energy_differential / temperature),\n" + ] + }, + "metadata": {}, + "output_type": "display_data" + } + ], + "source": [ + "from language import run_simulated_annealing\n", + "\n", + "optimized_program = run_simulated_annealing(\n", + " program=program,\n", + " initial_temperature=1.0,\n", + " annealing_rate=0.97,\n", + " total_num_steps=10_000,\n", + " folding_callback=folding_callback,\n", + " display_progress=True,\n", + ")\n", + "print(\"Final sequence = {}\".format(optimized_program.get_sequence_and_set_residue_index_ranges()[0]))" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "This program provides a minimal example of symmetric protein design, but we can also design much more complex proteins, as described in [our paper](https://www.biorxiv.org/content/10.1101/2022.12.21.521526v1).\n", + "\n", + "We provide example programs corresponding to our paper figures, as described in the table below:\n", + "\n", + "| Design task | Figure in paper | Program file |\n", + "|:--------------------------------------------|:---------------|:----------------------------------------------------------------------------|\n", + "| Free hallucination | Figure 2A | [free_hallucination.py](programs/free_hallucination.py) |\n", + "| Fixed backbone design | Figure 2D | [fixed_backbone.py](programs/fixed_backbone.py) |\n", + "| Secondary structure design | Figure 2G | [secondary_structure.py](programs/secondary_structure.py) |\n", + "| Functional site scaffolding | Figure 2H | [functional_site_scaffolding.py](programs/functional_site_scaffolding.py) |\n", + "| Symmetric monomer design | Figure 3A | [symmetric_monomer.py](programs/symmetric_monomer.py) |\n", + "| Two-level symmetric
homo-oligomer design | Figure 4A | [symmetric_two_level_multimer.py](programs/symmetric_two_level_multimer.py) |\n", + "| Symmetric binding site
scaffolding | Figure 5A | [symmetric_binding.py](programs/symmetric_binding.py) |\n", + "\n", + "These can easily be imported and run.\n", + "For example, the following code imports a symmetric binding site scaffolding program and computes the energy." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "from programs.symmetric_binding import symmetric_binding_il10\n", + "\n", + "program = symmetric_binding_il10()\n", + "\n", + "sequence, residue_indices = program.get_sequence_and_set_residue_index_ranges()\n", + "\n", + "folding_output = folding_callback.fold(sequence, residue_indices)\n", + "\n", + "energy_terms = program.get_energy_term_functions()\n", + "for name, weight, energy_fn in energy_terms:\n", + " print(f\"{name} = {weight:.1f} * {energy_fn(folding_output):.2f}\")" + ] + } + ], + "metadata": { + "kernelspec": { + "display_name": "Python 3 (ipykernel)", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.8.13" + } + }, + "nbformat": 4, + "nbformat_minor": 2 +} diff --git a/esm/source/examples/sup_variant_prediction.ipynb b/esm/source/examples/sup_variant_prediction.ipynb new file mode 100644 index 0000000000000000000000000000000000000000..22ea018afe441dcd743fa1e1eaad876c3b7df7c0 --- /dev/null +++ b/esm/source/examples/sup_variant_prediction.ipynb @@ -0,0 +1,1197 @@ +{ + "cells": [ + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "[![Open In Colab](https://colab.research.google.com/assets/colab-badge.svg)](https://colab.research.google.com/github/facebookresearch/esm/blob/master/examples/variant_prediction.ipynb)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "# Supervised variant prediction with ESM\n", + "\n", + "**Note, this example notebook predates our work on zero-shot variant prediction, which is presented in `examples/variant-prediction`**.\n", + "\n", + "This tutorial demonstrates how to train a simple variant predictor, i.e. we predict the biological activity of mutations of a protein, using fixed embeddings from ESM. You can adopt a similar protocol to train a model for any downstream task, even with limited data.\n", + "\n", + "We will use a simple classifier in sklearn (or \"head\" on top of the transformer features) to predict the mutation effect from precomputed ESM embeddings. The embeddings for your dataset can be dumped once using a GPU. Then, the rest of your analysis can be done on CPU. \n", + "\n", + "### Background\n", + "\n", + "In this particular example, we will train a model to predict the activity of ß-lactamase variants.\n", + "\n", + "We provide the training in `examples/data/P62593.fasta`, a FASTA file where each entry contains:\n", + "- the mutated ß-lactamase sequence, where a single residue is mutated (swapped with another amino acid)\n", + "- the target value in the last field of the header, describing the scaled effect of the mutation\n", + "\n", + "The [data originally comes](https://github.com/FowlerLab/Envision2017/blob/master/data/dmsTraining_2017-02-20.csv) from a deep mutational scan and was released with the Envision paper (Gray, et al. 2018)\n", + "\n", + "### Goals\n", + "- Obtain an embedding (fixed-dimensional vector representation) for each mutated sequence.\n", + "- Train a regression model in sklearn that can predict the \"effect\" score given the embedding.\n", + "\n", + "\n", + "### Prerequisites\n", + "- You will need the following modules : tqdm, matplotlib, numpy, pandas, seaborn, scipy, scikit-learn\n", + "- You have obtained sequence embeddings for ß-lactamase as described in the README:\n", + "```\n", + "python scripts/extract.py esm1v_t33_650M_UR90S_1 examples/data/P62593.fasta examples/data/P62593_emb_esm1v/ --repr_layers 33 --include mean\n", + "```\n" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Table of Contents\n", + "1. [Prelims](#prelims)\n", + "1. [Loading Embeddings](#load_embeddings)\n", + "1. [Visualizing Embeddings](#viz_embeddings)\n", + "1. [Initializing / Running Grid Search](#grid_search)\n", + "1. [Browse Grid Search Results](#browse)\n", + "1. [Evaluating Results](#eval)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "\n", + "## Prelims" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "If you are using colab, then uncomment and run the cell below.\n", + "It will pip install the `esm` code, fetch the fasta file and the pre-computed embeddings." + ] + }, + { + "cell_type": "code", + "execution_count": 1, + "metadata": {}, + "outputs": [], + "source": [ + "# !pip install git+https://github.com/facebookresearch/esm.git\n", + "# !curl -O https://dl.fbaipublicfiles.com/fair-esm/examples/P62593_reprs.tar.gz\n", + "# !tar -xzf P62593_reprs.tar.gz\n", + "# !curl -O https://dl.fbaipublicfiles.com/fair-esm/examples/P62593.fasta\n", + "# !pwd\n", + "# !ls" + ] + }, + { + "cell_type": "code", + "execution_count": 2, + "metadata": {}, + "outputs": [], + "source": [ + "import random\n", + "from collections import Counter\n", + "from tqdm import tqdm\n", + "\n", + "import torch\n", + "import matplotlib.pyplot as plt\n", + "import numpy as np\n", + "import pandas as pd\n", + "import seaborn as sns\n", + "\n", + "import esm" + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "metadata": {}, + "outputs": [], + "source": [ + "import scipy\n", + "from sklearn.model_selection import GridSearchCV, train_test_split\n", + "from sklearn.decomposition import PCA\n", + "from sklearn.neighbors import KNeighborsClassifier, KNeighborsRegressor\n", + "from sklearn.svm import SVC, SVR\n", + "from sklearn.ensemble import RandomForestClassifier, RandomForestRegressor\n", + "from sklearn.naive_bayes import GaussianNB\n", + "from sklearn.linear_model import LogisticRegression, SGDRegressor\n", + "from sklearn.pipeline import Pipeline" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "## Add the path to your embeddings here:\n" + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "metadata": {}, + "outputs": [], + "source": [ + "FASTA_PATH = \"./data/P62593.fasta\" # Path to P62593.fasta\n", + "EMB_PATH = \"./data/P62593_emb_esm1v/\" # Path to directory of embeddings for P62593.fasta\n", + "EMB_LAYER = 33" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "\n", + "## Load embeddings (Xs) and target effects (ys)\n", + "Our FASTA file is formatted as such:\n", + "```\n", + ">{index}|{mutation_id}|{effect}\n", + "{seq}\n", + "```\n", + "We will be extracting the effect from each entry.\n", + "\n", + "Our embeddings are stored with the file name from fasta header: `{index}|{mutation_id}|{effect}.pt`" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "5397\n", + "(5397, 1280)\n" + ] + } + ], + "source": [ + "ys = []\n", + "Xs = []\n", + "for header, _seq in esm.data.read_fasta(FASTA_PATH):\n", + " scaled_effect = header.split('|')[-1]\n", + " ys.append(float(scaled_effect))\n", + " fn = f'{EMB_PATH}/{header[1:]}.pt'\n", + " embs = torch.load(fn)\n", + " Xs.append(embs['mean_representations'][EMB_LAYER])\n", + "Xs = torch.stack(Xs, dim=0).numpy()\n", + "print(len(ys))\n", + "print(Xs.shape)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Train / Test Split\n", + "\n", + "Here we choose to follow the Envision paper, using 80% of the data for training, but we actually found that pre-trained ESM embeddings require fewer downstream training examples to reach the same level of performance." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "train_size = 0.8\n", + "Xs_train, Xs_test, ys_train, ys_test = train_test_split(Xs, ys, train_size=train_size, random_state=42)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "((4317, 1280), (1080, 1280), 4317, 1080)" + ] + }, + "execution_count": 7, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "Xs_train.shape, Xs_test.shape, len(ys_train), len(ys_test)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### PCA\n", + "\n", + "Principal Component Analysis is a popular technique for dimensionality reduction. Given `n_features` (1280 in our case), PCA computes a new set of `X` that \"best explain the data.\" We've found that this enables downstream models to be trained faster with minimal loss in performance. \n", + "\n", + "Here, we set `X` to 60, but feel free to change it!\n" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "num_pca_components = 60\n", + "pca = PCA(num_pca_components)\n", + "Xs_train_pca = pca.fit_transform(Xs_train)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "\n", + "## Visualize Embeddings\n", + "\n", + "Here, we plot the first two principal components on the x- and y- axes. Each point is then colored by its scaled effect (what we want to predict).\n", + "\n", + "Visually, we can see a separation based on color/effect, suggesting that our representations are useful for this task, without any task-specific training!" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "" + ] + }, + "execution_count": 9, + "metadata": {}, + "output_type": "execute_result" + }, + { + "data": { + "image/png": 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\n", + "text/plain": [ + "
" + ] + }, + "metadata": { + "needs_background": "light" + }, + "output_type": "display_data" + } + ], + "source": [ + "fig_dims = (7, 6)\n", + "fig, ax = plt.subplots(figsize=fig_dims)\n", + "sc = ax.scatter(Xs_train_pca[:,0], Xs_train_pca[:,1], c=ys_train, marker='.')\n", + "ax.set_xlabel('PCA first principal component')\n", + "ax.set_ylabel('PCA second principal component')\n", + "plt.colorbar(sc, label='Variant Effect')" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "\n", + "\n", + "## Initialize / Run GridSearch\n", + "\n", + "We will run grid search for three different regression models:\n", + "1. [K-nearest-neighbors](https://scikit-learn.org/stable/modules/generated/sklearn.neighbors.KNeighborsRegressor.html)\n", + "2. [SVM](https://scikit-learn.org/stable/modules/generated/sklearn.svm.SVR.html?highlight=svr#sklearn.svm.SVR)\n", + "3. [Random Forest Regressor](https://scikit-learn.org/stable/modules/generated/sklearn.ensemble.RandomForestRegressor.html?highlight=randomforestregressor#sklearn.ensemble.RandomForestRegressor)\n", + "\n", + "Here, we will be using the PCA-projected features because we observe it does just as well as `Xs` while allowing for faster training. You can easily swap it out for `Xs`." + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Initialize grids for different regression techniques" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "knn_grid = [\n", + " {\n", + " 'model': [KNeighborsRegressor()],\n", + " 'model__n_neighbors': [5, 10],\n", + " 'model__weights': ['uniform', 'distance'],\n", + " 'model__algorithm': ['ball_tree', 'kd_tree', 'brute'],\n", + " 'model__leaf_size' : [15, 30],\n", + " 'model__p' : [1, 2],\n", + " }\n", + " ]\n", + "\n", + "svm_grid = [\n", + " {\n", + " 'model': [SVR()],\n", + " 'model__C' : [0.1, 1.0, 10.0],\n", + " 'model__kernel' : ['linear', 'poly', 'rbf', 'sigmoid'],\n", + " 'model__degree' : [3],\n", + " 'model__gamma': ['scale'],\n", + " }\n", + "]\n", + "\n", + "rfr_grid = [\n", + " {\n", + " 'model': [RandomForestRegressor()],\n", + " 'model__n_estimators' : [20],\n", + " 'model__criterion' : ['squared_error', 'absolute_error'],\n", + " 'model__max_features': ['sqrt', 'log2'],\n", + " 'model__min_samples_split' : [5, 10],\n", + " 'model__min_samples_leaf': [1, 4]\n", + " }\n", + "]" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "cls_list = [KNeighborsRegressor, SVR, RandomForestRegressor]\n", + "param_grid_list = [knn_grid, svm_grid, rfr_grid]" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Run Grid Search \n", + "\n", + "(will take a few minutes on a single core)" + ] + }, + { + "cell_type": "code", + "execution_count": 14, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "\n", + "Fitting 5 folds for each of 48 candidates, totalling 240 fits\n", + "\n", + "Fitting 5 folds for each of 12 candidates, totalling 60 fits\n", + "\n", + "Fitting 5 folds for each of 16 candidates, totalling 80 fits\n" + ] + } + ], + "source": [ + "# make sure data preprocessing (PCA here) is run inside CV to avoid data leakage\n", + "pipe = Pipeline(\n", + " steps = (\n", + " ('pca', PCA(num_pca_components)),\n", + " ('model', 'passthrough')\n", + " )\n", + ")\n", + "\n", + "result_list = []\n", + "grid_list = []\n", + "for cls_name, param_grid in zip(cls_list, param_grid_list):\n", + " print(cls_name)\n", + " grid = GridSearchCV(\n", + " estimator = pipe,\n", + " param_grid = param_grid,\n", + " scoring = 'r2',\n", + " verbose = 1,\n", + " n_jobs = -1 # use all available cores\n", + " )\n", + " grid.fit(Xs_train, ys_train)\n", + " result_list.append(pd.DataFrame.from_dict(grid.cv_results_))\n", + " grid_list.append(grid)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "\n", + "## Browse the Sweep Results\n", + "\n", + "The following tables show the top 5 parameter settings, based on `mean_test_score`. Given our setup, this should really be thought of as `validation_score`." + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### K Nearest Neighbors" + ] + }, + { + "cell_type": "code", + "execution_count": 15, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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mean_fit_timestd_fit_timemean_score_timestd_score_timeparam_modelparam_model__algorithmparam_model__leaf_sizeparam_model__n_neighborsparam_model__pparam_model__weightsparamssplit0_test_scoresplit1_test_scoresplit2_test_scoresplit3_test_scoresplit4_test_scoremean_test_scorestd_test_scorerank_test_score
91.8618670.2832380.8160560.063010KNeighborsRegressor(algorithm='ball_tree', p=1...ball_tree3051distance{'model': KNeighborsRegressor(algorithm='ball_...0.6950100.7056080.6579990.6446950.6651640.6736950.0229471
11.7651020.2070290.6898000.216780KNeighborsRegressor(algorithm='ball_tree', p=1...ball_tree1551distance{'model': KNeighborsRegressor(algorithm='ball_...0.6902650.7015570.6610570.6495080.6654270.6735630.0193072
170.5891930.0998921.4221660.152255KNeighborsRegressor(algorithm='ball_tree', p=1...kd_tree1551distance{'model': KNeighborsRegressor(algorithm='ball_...0.6932050.7009610.6639980.6480630.6598840.6732220.0203213
331.2842000.4962191.2029150.300557KNeighborsRegressor(algorithm='ball_tree', p=1...brute1551distance{'model': KNeighborsRegressor(algorithm='ball_...0.6928010.6986000.6612470.6492490.6609640.6725720.0194614
411.3631550.4164160.3703800.174864KNeighborsRegressor(algorithm='ball_tree', p=1...brute3051distance{'model': KNeighborsRegressor(algorithm='ball_...0.6959180.7012950.6554340.6418030.6611020.6711100.0233725
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" + ], + "text/plain": [ + " mean_fit_time std_fit_time mean_score_time std_score_time \\\n", + "9 1.861867 0.283238 0.816056 0.063010 \n", + "1 1.765102 0.207029 0.689800 0.216780 \n", + "17 0.589193 0.099892 1.422166 0.152255 \n", + "33 1.284200 0.496219 1.202915 0.300557 \n", + "41 1.363155 0.416416 0.370380 0.174864 \n", + "\n", + " param_model param_model__algorithm \\\n", + "9 KNeighborsRegressor(algorithm='ball_tree', p=1... ball_tree \n", + "1 KNeighborsRegressor(algorithm='ball_tree', p=1... ball_tree \n", + "17 KNeighborsRegressor(algorithm='ball_tree', p=1... kd_tree \n", + "33 KNeighborsRegressor(algorithm='ball_tree', p=1... brute \n", + "41 KNeighborsRegressor(algorithm='ball_tree', p=1... brute \n", + "\n", + " param_model__leaf_size param_model__n_neighbors param_model__p \\\n", + "9 30 5 1 \n", + "1 15 5 1 \n", + "17 15 5 1 \n", + "33 15 5 1 \n", + "41 30 5 1 \n", + "\n", + " param_model__weights params \\\n", + "9 distance {'model': KNeighborsRegressor(algorithm='ball_... \n", + "1 distance {'model': KNeighborsRegressor(algorithm='ball_... \n", + "17 distance {'model': KNeighborsRegressor(algorithm='ball_... \n", + "33 distance {'model': KNeighborsRegressor(algorithm='ball_... \n", + "41 distance {'model': KNeighborsRegressor(algorithm='ball_... \n", + "\n", + " split0_test_score split1_test_score split2_test_score \\\n", + "9 0.695010 0.705608 0.657999 \n", + "1 0.690265 0.701557 0.661057 \n", + "17 0.693205 0.700961 0.663998 \n", + "33 0.692801 0.698600 0.661247 \n", + "41 0.695918 0.701295 0.655434 \n", + "\n", + " split3_test_score split4_test_score mean_test_score std_test_score \\\n", + "9 0.644695 0.665164 0.673695 0.022947 \n", + "1 0.649508 0.665427 0.673563 0.019307 \n", + "17 0.648063 0.659884 0.673222 0.020321 \n", + "33 0.649249 0.660964 0.672572 0.019461 \n", + "41 0.641803 0.661102 0.671110 0.023372 \n", + "\n", + " rank_test_score \n", + "9 1 \n", + "1 2 \n", + "17 3 \n", + "33 4 \n", + "41 5 " + ] + }, + "execution_count": 15, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "result_list[0].sort_values('rank_test_score')[:5]" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### SVM" + ] + }, + { + "cell_type": "code", + "execution_count": 16, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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mean_fit_timestd_fit_timemean_score_timestd_score_timeparam_modelparam_model__Cparam_model__degreeparam_model__gammaparam_model__kernelparamssplit0_test_scoresplit1_test_scoresplit2_test_scoresplit3_test_scoresplit4_test_scoremean_test_scorestd_test_scorerank_test_score
61.5960570.3748110.1872320.012077SVR()1.03scalerbf{'model': SVR(), 'model__C': 1.0, 'model__degr...0.7370710.7264060.6784420.7022080.6893380.7066930.0220491
102.0307720.2788080.1832480.008195SVR()10.03scalerbf{'model': SVR(), 'model__C': 10.0, 'model__deg...0.7014820.7133770.6716240.6910040.6810540.6917080.0147142
21.5597520.2089160.2188850.045596SVR()0.13scalerbf{'model': SVR(), 'model__C': 0.1, 'model__degr...0.6435680.6215540.5749860.6106640.5780710.6057690.0261413
52.0629630.2097790.0787160.004191SVR()1.03scalepoly{'model': SVR(), 'model__C': 1.0, 'model__degr...0.5238320.4251240.4483380.4762810.4183980.4583950.0384964
81.4572020.3694960.0799030.004191SVR()10.03scalelinear{'model': SVR(), 'model__C': 10.0, 'model__deg...0.4848580.4466880.4345470.4426080.4326030.4482610.0190115
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" + ], + "text/plain": [ + " mean_fit_time std_fit_time mean_score_time std_score_time param_model \\\n", + "6 1.596057 0.374811 0.187232 0.012077 SVR() \n", + "10 2.030772 0.278808 0.183248 0.008195 SVR() \n", + "2 1.559752 0.208916 0.218885 0.045596 SVR() \n", + "5 2.062963 0.209779 0.078716 0.004191 SVR() \n", + "8 1.457202 0.369496 0.079903 0.004191 SVR() \n", + "\n", + " param_model__C param_model__degree param_model__gamma param_model__kernel \\\n", + "6 1.0 3 scale rbf \n", + "10 10.0 3 scale rbf \n", + "2 0.1 3 scale rbf \n", + "5 1.0 3 scale poly \n", + "8 10.0 3 scale linear \n", + "\n", + " params split0_test_score \\\n", + "6 {'model': SVR(), 'model__C': 1.0, 'model__degr... 0.737071 \n", + "10 {'model': SVR(), 'model__C': 10.0, 'model__deg... 0.701482 \n", + "2 {'model': SVR(), 'model__C': 0.1, 'model__degr... 0.643568 \n", + "5 {'model': SVR(), 'model__C': 1.0, 'model__degr... 0.523832 \n", + "8 {'model': SVR(), 'model__C': 10.0, 'model__deg... 0.484858 \n", + "\n", + " split1_test_score split2_test_score split3_test_score \\\n", + "6 0.726406 0.678442 0.702208 \n", + "10 0.713377 0.671624 0.691004 \n", + "2 0.621554 0.574986 0.610664 \n", + "5 0.425124 0.448338 0.476281 \n", + "8 0.446688 0.434547 0.442608 \n", + "\n", + " split4_test_score mean_test_score std_test_score rank_test_score \n", + "6 0.689338 0.706693 0.022049 1 \n", + "10 0.681054 0.691708 0.014714 2 \n", + "2 0.578071 0.605769 0.026141 3 \n", + "5 0.418398 0.458395 0.038496 4 \n", + "8 0.432603 0.448261 0.019011 5 " + ] + }, + "execution_count": 16, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "result_list[1].sort_values('rank_test_score')[:5]" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Random Forest" + ] + }, + { + "cell_type": "code", + "execution_count": 17, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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mean_fit_timestd_fit_timemean_score_timestd_score_timeparam_modelparam_model__criterionparam_model__max_featuresparam_model__min_samples_leafparam_model__min_samples_splitparam_model__n_estimatorsparamssplit0_test_scoresplit1_test_scoresplit2_test_scoresplit3_test_scoresplit4_test_scoremean_test_scorestd_test_scorerank_test_score
41.1855520.1320150.0151650.000395RandomForestRegressor(max_features='log2', min...squared_errorlog21520{'model': RandomForestRegressor(max_features='...0.5339330.5301090.5034190.5193530.4670330.5107690.0242951
11.3343410.1106250.0127100.001579RandomForestRegressor(max_features='log2', min...squared_errorsqrt11020{'model': RandomForestRegressor(max_features='...0.5392300.5108090.4819120.5288060.4797650.5081050.0240582
01.4457420.1180840.0133530.001643RandomForestRegressor(max_features='log2', min...squared_errorsqrt1520{'model': RandomForestRegressor(max_features='...0.5305010.5140210.4911990.5167430.4876620.5080250.0162173
21.4957290.1246260.0108260.000706RandomForestRegressor(max_features='log2', min...squared_errorsqrt4520{'model': RandomForestRegressor(max_features='...0.5145460.5333790.4791040.5186050.4599180.5011100.0272364
812.1515971.0927830.0108620.001263RandomForestRegressor(max_features='log2', min...absolute_errorsqrt1520{'model': RandomForestRegressor(max_features='...0.5057190.5026440.4701060.5119160.4683950.4917560.0186255
\n", + "
" + ], + "text/plain": [ + " mean_fit_time std_fit_time mean_score_time std_score_time \\\n", + "4 1.185552 0.132015 0.015165 0.000395 \n", + "1 1.334341 0.110625 0.012710 0.001579 \n", + "0 1.445742 0.118084 0.013353 0.001643 \n", + "2 1.495729 0.124626 0.010826 0.000706 \n", + "8 12.151597 1.092783 0.010862 0.001263 \n", + "\n", + " param_model param_model__criterion \\\n", + "4 RandomForestRegressor(max_features='log2', min... squared_error \n", + "1 RandomForestRegressor(max_features='log2', min... squared_error \n", + "0 RandomForestRegressor(max_features='log2', min... squared_error \n", + "2 RandomForestRegressor(max_features='log2', min... squared_error \n", + "8 RandomForestRegressor(max_features='log2', min... absolute_error \n", + "\n", + " param_model__max_features param_model__min_samples_leaf \\\n", + "4 log2 1 \n", + "1 sqrt 1 \n", + "0 sqrt 1 \n", + "2 sqrt 4 \n", + "8 sqrt 1 \n", + "\n", + " param_model__min_samples_split param_model__n_estimators \\\n", + "4 5 20 \n", + "1 10 20 \n", + "0 5 20 \n", + "2 5 20 \n", + "8 5 20 \n", + "\n", + " params split0_test_score \\\n", + "4 {'model': RandomForestRegressor(max_features='... 0.533933 \n", + "1 {'model': RandomForestRegressor(max_features='... 0.539230 \n", + "0 {'model': RandomForestRegressor(max_features='... 0.530501 \n", + "2 {'model': RandomForestRegressor(max_features='... 0.514546 \n", + "8 {'model': RandomForestRegressor(max_features='... 0.505719 \n", + "\n", + " split1_test_score split2_test_score split3_test_score split4_test_score \\\n", + "4 0.530109 0.503419 0.519353 0.467033 \n", + "1 0.510809 0.481912 0.528806 0.479765 \n", + "0 0.514021 0.491199 0.516743 0.487662 \n", + "2 0.533379 0.479104 0.518605 0.459918 \n", + "8 0.502644 0.470106 0.511916 0.468395 \n", + "\n", + " mean_test_score std_test_score rank_test_score \n", + "4 0.510769 0.024295 1 \n", + "1 0.508105 0.024058 2 \n", + "0 0.508025 0.016217 3 \n", + "2 0.501110 0.027236 4 \n", + "8 0.491756 0.018625 5 " + ] + }, + "execution_count": 17, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "result_list[2].sort_values('rank_test_score')[:5]" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "\n", + "## Evaluation\n", + "\n", + "Now that we have run grid search, each `grid` object contains a `best_estimator_`.\n", + "\n", + "We can use this to evaluate the correlation between our predictions and the true effect scores on the held-out validation set." + ] + }, + { + "cell_type": "code", + "execution_count": 18, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "KNeighborsRegressor(algorithm='ball_tree', p=1, weights='distance')\n", + "\n", + "SpearmanrResult(correlation=0.8065398315270731, pvalue=2.4681127050485095e-248)\n", + "\n", + " -------------------------------------------------------------------------------- \n", + "\n", + "SVR()\n", + "\n", + "SpearmanrResult(correlation=0.8147793655720186, pvalue=1.8403540985305893e-257)\n", + "\n", + " -------------------------------------------------------------------------------- \n", + "\n", + "RandomForestRegressor(max_features='log2', min_samples_split=5, n_estimators=20)\n", + "\n", + "SpearmanrResult(correlation=0.7277072328713822, pvalue=1.0094601306397444e-178)\n", + "\n", + " -------------------------------------------------------------------------------- \n", + "\n" + ] + } + ], + "source": [ + "for grid in grid_list:\n", + " print(grid.best_estimator_.get_params()[\"steps\"][1][1]) # get the model details from the estimator\n", + " print()\n", + " preds = grid.predict(Xs_test)\n", + " print(f'{scipy.stats.spearmanr(ys_test, preds)}')\n", + " print('\\n', '-' * 80, '\\n')\n" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "The SVM performs the best on the `test` set, with a spearman rho of 0.815! \n", + "\n", + "This is in line with our grid-search results, where it also had the best `validation` performance.\n", + "\n", + "In conclusion, our downstream model was able to use fixed pre-trained ESM embedding representations and obtain a decent result.\n", + "\n", + "For reference, we report correlation of 0.89 in Table 7 of [Rives et al.](https://www.biorxiv.org/content/10.1101/622803v3), but this was achieved by fine-tuning the model, and with ESM-1, before we developed ESM-1v." + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "**For zero-shot variant prediction, see `examples/variant-prediction`**" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [] + } + ], + "metadata": { + "kernelspec": { + "display_name": "Python 3 (ipykernel)", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.8.12" + } + }, + "nbformat": 4, + "nbformat_minor": 4 +} diff --git a/esm/source/examples/variant-prediction/README.md b/esm/source/examples/variant-prediction/README.md new file mode 100644 index 0000000000000000000000000000000000000000..fa1c6e86c2fa7b01360c255bdc822fbdbbeda99a --- /dev/null +++ b/esm/source/examples/variant-prediction/README.md @@ -0,0 +1,44 @@ +# Zero-shot variant prediction with protein language models + +This folder contains code and pre-trained weights for the ESM-1v models described in +[Language models enable zero-shot prediction of the effects of mutations on protein function. (Meier et al. 2021)](https://doi.org/10.1101/2021.07.09.450648). + +### Labeling a deep mutational scan with model predictions + +Given a deep mutational scan and its associated sequence, the effects of mutations can be predicted using an ensemble of five ESM-1v models: +``` +python predict.py \ + --model-location esm1v_t33_650M_UR90S_1 esm1v_t33_650M_UR90S_2 esm1v_t33_650M_UR90S_3 esm1v_t33_650M_UR90S_4 esm1v_t33_650M_UR90S_5 \ + --sequence HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW \ + --dms-input ./data/BLAT_ECOLX_Ranganathan2015.csv \ + --mutation-col mutant \ + --dms-output ./data/BLAT_ECOLX_Ranganathan2015_labeled.csv \ + --offset-idx 24 \ + --scoring-strategy wt-marginals +``` + +Similarly, one could use the MSA Transformer: +``` +python predict.py \ + --model-location esm_msa1b_t12_100M_UR50S \ + --sequence HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW \ + --dms-input ./data/BLAT_ECOLX_Ranganathan2015.csv \ + --mutation-col mutant \ + --dms-output ./data/BLAT_ECOLX_Ranganathan2015_labeled.csv \ + --offset-idx 24 \ + --scoring-strategy masked-marginals \ + --msa-path ./data/BLAT_ECOLX_1_b0.5.a3m +``` + +### Per-task performance +In `data/` we also release result data files of model predictions of the 41 Deep Mutational Scanning datasets reported in the paper +[Language models enable zero-shot prediction of the effects of mutations on protein function. (Meier et al. 2021)](https://doi.org/10.1101/2021.07.09.450648). + +The order of the datasets matches the paper Figure 3 and Figure 8; +the first 10 proteins are validation proteins used during method development, and the next 31 are test proteins. + +Note the three different levels of aggregation: +* `raw_df` \[[LINK](https://dl.fbaipublicfiles.com/fair-esm/examples/variant-prediction/data/raw_df.csv)\]: every row contains one mutation for a specific protein (multi-index: ["protein_name", "mutant"]) and columns are different prediction methods. +* `rho_pp` dataframe (rho per protein): contains the main metric absolute value of spearman rho per protein summarizing how good a prediction method performs on that protein. Other two fields `rho_boot_mean, rho_boot_std` are the mean and standard deviation of 20 bootstrapped samples. +* `aggregated_rho`: the performance metrics from `rho_pp` averaged over the proteins from the valid / full / test set. There is a multi-index header `(valid / full / test) x (rho / rho_boot_mean / rho_boot_std)` + diff --git a/esm/source/examples/variant-prediction/__init__.py b/esm/source/examples/variant-prediction/__init__.py new file mode 100644 index 0000000000000000000000000000000000000000..e69de29bb2d1d6434b8b29ae775ad8c2e48c5391 diff --git a/esm/source/examples/variant-prediction/data/BLAT_ECOLX_1_b0.5.a3m b/esm/source/examples/variant-prediction/data/BLAT_ECOLX_1_b0.5.a3m new file mode 100644 index 0000000000000000000000000000000000000000..82bd3340e22505f617c208b7d82881bc6c1857c8 --- /dev/null +++ b/esm/source/examples/variant-prediction/data/BLAT_ECOLX_1_b0.5.a3m @@ -0,0 +1,153366 @@ +>BLAT_ECOLX/24-286 +hpETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Uncharacterized protein n=326 Tax=root TaxID=1 RepID=A0A077REW6_WHEAT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPD------------- +----------------------- +>[subseq from] Uncharacterized protein n=326 Tax=root TaxID=1 RepID=A0A077REW6_WHEAT +-----VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0005DE4B21 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAXS- +------------------------------------------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0005DE4B21 +------------------------------------------------------------ +---ALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] BETA-LACTAMASE n=1 Tax=synthetic construct TaxID=32630 RepID=UPI0004437F73 +--ALNDEFAALEKQYGGRLGVYALDTGTGRTI-AYRADERFPMCSTFKALAAAAVLAQVD +AGKESLDRRITYTKDDLVDYSPVTEKHVGTGMTLAELCEAAITYSDNTAANLLLDEIGGP +KGLTAFLRSIGDDVTRLDRWEPELNEALPGDPRDTTTPAAMAATLRALLLGDALSPASRA +QLTDWMRGNTTGDKLIRAGLPAGWRVGDKTGTGSYGTRNDIAIIWPPNRAPIVLAIYSTG +STADAKERNALIAEAAKIVAE-- +>[subseq from] BETA-LACTAMASE n=1 Tax=synthetic construct TaxID=32630 RepID=UPI0004437F29 +--ALSEQLAELEKRSGGRLGVAVLDTATGRRI-AYRGDERFPMCSTFKALLAAAVLAQVD +QGKERLDRRITYSKADLVDYSPVTEKHVGGGMTVAELCEAAITYSDNTAANLLLEALGGP +AALTAFLRSIGDEVTRLDRWEPELNEALPGDPRDTTTPRAMAATLRKLLLGDALSPASRE +QLVDWLLANKTGDKRLRAGLPADWRVGDKTGTGGHGTTNDIAVIWPPNRAPIVVAVYYTE +SQADAEARDAVIAEVGRLVAEAf +>[subseq from] GNCA BETA LACTAMASE n=2 Tax=synthetic construct TaxID=32630 RepID=UPI000957C7BE +--QLSEQLAELEKRSGGRLGVAVLDTATGRRI-AYRGDERFPMCSTFKALLAAAVLARVD +QGKERLDRRITYGKEDLVDYSPVTEKHVGDGMTVAELCEAAITLSDNTAANLLLEALGGP +AALTAFLRSIGDEVTRLDRWEPELNEAAPGDPRDTTTPAAMAATLRTLLLGDALSPASRQ +QLVDWLVANKTGDKRLRAGLPADWRVGDKTGTGGHGTTNDIAVIWPPGRAPIVVTVYLTE +SQVDADARDAVIAEVGRLVVEAf +>[subseq from] GNCA4 LACTAMASE n=1 Tax=synthetic construct TaxID=32630 RepID=UPI0009468CF7 +--ALSEQLAELEKRSGGRLGVAVLDTATGRRF-GYRGDERFPMCSTFKALLAAAVLARVD +QGKENLDRRITYGKEDLVDYSPVTEKHVGDGMTVAELCEAAITYSDNTAANLLLEALGGP +AALTAFLRSIGDNVTRLDRWEPELNTAAPGDPRDTTTPAAMAATLRTLLLGDVLSPASRQ +QLVDWLIANKTGDKRLRAGLPADWRVGDKTGTGEHGTTNDIAVIWPPNRAPILVAVYLTE +SQVDADARDAVIAEVARLVVAAf +>[subseq from] GNCA LACTAMASE W229D n=1 Tax=synthetic construct TaxID=32630 RepID=UPI0007A93677 +--QLSEQLAELEKRSGGRLGVAVLDTATGRRI-AYRGDERFPMCSTFKALLAAAVLARVD +QGKERLDRRITYGKEDLVDYSPVTEKHVGDGMTVAELCEAAITLSDNTAANLLLEALGGP +AALTAFLRSIGDEVTRLDRWEPELNEAAPGDPRDTTTPAAMAATLRTLLLGDALSPASRQ +QLVDWLVANKTGDKRLRAGLPADDRVGDKTGTGGHGTTNDIAVIWPPGRAPIVVTVYLTE +SQVDADARDAVIAEVGRLVVEAf +>[subseq from] GNCA4 LACTAMASE W229D AND F290W n=1 Tax=synthetic construct TaxID=32630 RepID=UPI0009388698 +--ALSEQLAELEKRSGGRLGVAVLDTATGRRF-GYRGDERFPMCSTFKALLAAAVLARVD +QGKENLDRRITYGKEDLVDYSPVTEKHVGDGMTVAELCEAAITYSDNTAANLLLEALGGP +AALTAFLRSIGDNVTRLDRWEPELNTAAPGDPRDTTTPAAMAATLRTLLLGDVLSPASRQ +QLVDWLIANKTGDKRLRAGLPADDRVGDKTGTGEHGTTNDIAVIWPPNRAPILVAVYLTE +SQVDADARDAVIAEVARLVVAAw +>[subseq from] Beta-lactamase n=41 Tax=root TaxID=1 RepID=Q52089_9ZZZZ +------------------------------------------------------------ +---------------------------LADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia metallica TaxID=488729 RepID=UPI000D1B824A +---AAQMFAELERSAGGRLGVCAIDIATGRRA-EHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTQADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGDALPPAQRA +QLVTWMRGNKVGDKRLRAGVPAGWTVADKTGTGDYGTTNDAGVVWSPSRAPIALAVYYTQ +ARADARAKDDVIASVARIVVQAf +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Burkholderia TaxID=32008 RepID=F0GIV5_9BURK +---AYDALQALERDAGGRLGVYAVDTASGRSV-EHRPNERFPFCSTFKAMLAAAVLAQSV +ERPALLQQRVTYGKADLVNYSPVSGKHVDTGMTVAELCAAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLALGDALPAAQRA +QLVEWLRGNKVGDKRIRAGVPAGWQVGDKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADARAKDDVIAAVARIAVAAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264) TaxID=271848 RepID=UPI000980150C +--AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAVLARSA +GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRL------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia metallica TaxID=488729 RepID=A0A1B4I592_9BURK +---AAQMFAELERSAGGRVGVCAIDIATGRRA-EHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYSQADLVNYSPVSEKHVGTGMTVAALCEAAIQYSDNSAANLLLKMLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGDALPPAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVADKTGTGDYGTTNDAGVVWSPSRTPIALAVYYTQ +ARADARAKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0007593DDF +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLCAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp9131 TaxID=2184571 RepID=A0A3N8AB34_9BURK +----ATSFAALERAAGGRLGVCAIDTAGGRRV-QHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVAVAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ +TRADAKAKDDVIAAAARIAVATf +>[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas palustris TaxID=1076 RepID=UPI000CEBB9BD +--ALADMCARLEAGSGGRLGVCVLDTASGRMI-GHRLDERFPMCSTFKALAAGLVLARVD +RKQENLDRRVSYAKSDLVTYSPATEKHVEDGMTIAELCEAAITLSDNTAANLLLASFGGP +AGLTAFARSLGDETTRLDRIETELNEALPGDPRDTTSPRAMAQDLRALTLGDALSPASRA +QLITWLKANTTGGTRLRAGVPPGWTVGDKTGTGGRGTANDIAVLWPPQRAPLIVTVYLTG +ATVSRDQQNKIIADVGAAVAD-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000757D79E +-----ASFAALERAAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075C4B1B +-----QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV +ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWPPSRAPIAVAVYYTQ +ARADARSKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000F50CFCC +-----ASFAALERAAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0012DC2EFD +-----ASFAALERAAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0012DEF938 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSLGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0004F8B564 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075679A2 +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSA +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVTWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFD2CD +-----ASFAALERAAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D00CCF5 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia multivorans CGD1 TaxID=513051 RepID=B9AYU4_9BURK +-----ASFAALERAAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. TSO22-1 TaxID=716789 RepID=A0A2U1WMN1_9PROT +--DLGGTLAALEKRIDARLGVAVLDTATGRSW-GHRADERFPMCSTFKALACGAVLARVD +EGKERLDRRVRYTAGDLVTYSPATKEGVGAGMTVAEICEAAMTLSDNTAANLILDSLGGP +VALTAFVRSLGDAVTRLDRRETELNTAIPGDPRDTTTPAAMAGSLRALAVGDHLSASSRE +QFNAWMVATRTGDARLRAGLPKDWRIGDKTGTGDHGTANDVAVIWPPGRKPLVVSVYVTQ +TKASLDDRNAAIAEVGRLV---- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia cepacia complex TaxID=87882 RepID=A0A087NXY8_BURPY +--AAAAALAHLERDAGGRLGVCAIDTASGRRV-AHRAAERFPFCSTFKAMLSAAVLAQSV +ARPGLLQQRVTYGKADLVNYSPVTEKHVGAGMTVAELCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPAAQRA +QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWAPSRAPIVLAVYYTQ +ARADARAKDDVIADVARVVVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0012DE8F05 +-----ASFAALEREAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIA---- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI000F582E9A +----ATSFAALERAAGGRLGVCAIDTAGGRRV-QHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVAVAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ +TRADAKAKDDVIAAAARIAVATf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075ABC6A +----GQTLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +TRADARSKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI001248539F +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0006C7CDCB +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLCAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=A0A125K4J2_9BURK +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAAARIAVAAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A1Y1BME3_9BURK +---AAATFAQLERDAGGRLGVCAIDTASGRRV-AHRADERFPFCSTFKAMLSAAVLAQSV +ARPGLLQQRVTYGKADLVNYSPVTGKHVDAGMTVAELCEATIQYSDNAAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPTRAPIVLVVYYTQ +AHADARAKDDVIADVARVVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=A0A132E9M4_9BURK +---AYDALQALERDAGGRLGVYAIDTASGRSV-AYRPNERFPFCSTFKAMLGAAVLAQSV +ARPALLQQRVTYGKADLVNYSPVSGKHVDTGMTVAELCAAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLALGDALPAAQRA +QLVEWLRGNKVGDKRIRAGVPAGWQVGDKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAHAKDDVIAAVARIVAAAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia GG4 TaxID=1009846 RepID=J7J6R5_BURCE +----ATTFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYGQSDLVNYSPVSGKHVGTGMTVAELCAAAIQYSDNSAANLAMKLIGGP +AAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLHALTLGEALPPAQRA +QLVAWLRGNQVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ +ARADAKPKDDVIAAAARIAAATf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=A0A3P0CDT7_9BURK +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV +EQPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRE +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDVGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVARTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. JP2-270 TaxID=2217913 RepID=A0A2U9SSR5_9BURK +--AAAATFADLERDAGGRLGVCAIDTASGRRV-AHRAAERFPFCSTFKAMLSAAVLAQSV +ARPGLLQQRVTYGKADLVNYSPVTEKHVGVGMTVAELCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPAAQRA +QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWAPSRAPIVLAVYYTQ +ARADARAKDDVIADVARVVVAAf +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3R9BAB6_9BURK +---AATTLADLERDAGGRLGVCAIDTASGRII-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] Beta-lactamase n=1 Tax=Caballeronia arationis TaxID=1777142 RepID=A0A158C2S8_9BURK +-qSAASQLKALEAASNGRLGVAALNTGDGAIV-NYRADERFPFCSTFKVLLASAILTRSA +HEDGLLDQRIRYTQSDLVNYSPVSEKHVADGMTVAELCAAAIQYSDNSAANLLIRLLGGP +PAVTAFARSIGDDEFRLDRMETELNTAIPGDLRDTTTPAAMARSLQRLALGNALGARERD +QLQAWMRGNTTGDARIRAGVPRDWQVADKTGTGDYGTSNDVAVLWPPSKPPIVVVIYFTQ +REQDAKARSDVLASAAKIVARKf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0007526BF2 +-----ASFAALEREAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRVA---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas sp. BR0M22 TaxID=2269369 RepID=UPI0013DF4E0D +--ALSEPCARLEAESGGRLGVGVLDTASGRTI-GHRLDERFPMCSTFKVLAAGLVLARVD +RKQESLDRRVSYAKSDLVTYSPATEKHVEGGMTIAELCEAAITLSDNTAGNLLLASFGGP +AGLTTFARSLGDDTTRLDRIETELNEALPGDPRDTTSPRAMAQDLRALTLGDALSPASRA +QLITWLKANTTGGTRLRAGVPTGWTVGDKTGTGDRGTANDVAVIWPPQRAPLIVTVYLTG +ATVARDQQNKIIADVGAEVVRAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3Q9FEF4_9BURK +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075FFF57 +---AGQTLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV +ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARSKDDVIASVARIVVQAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia (strain AU 1054) TaxID=331271 RepID=A0A0H2XVR0_BURCA +---AATTLADLERDAGGRLGVCAIDTASGRII-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGGYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas sacheonensis TaxID=443615 RepID=UPI0013D0C5DC +--DANSRLQALESVHGGRLGVSIFDTGTGKRI-GHRADERFPMCSTFKFLAAAQVLARVD +RGEERLDRRVVYTKDDLVAYSPVTEKHVGTGMTLAELCHATVTVSDNTAGNLLLASFGGP +AGLTAFARSLGDGVTRLDRWETELNEAVPGDPRDTTSPAAMLEDMRSLLLGDTLSPASRK +QLADWLVATTTGDKRIRGGLPKEWRAGDKTGTSNNGVTNDIAIVWPPGRAPLLVTAYYAE +YPQPQEARNAVIAEVGRIAA--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFF887E +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLAAAVLAQSV +EHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075ACFD5 +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007593C38 +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI000757E74C +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007537933 +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVAAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=A0A1B4C0W4_9BURK +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLEQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAAARIAVATf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=A0A132EYV1_9BURK +---AYDALQALEREAGGRLGVYAVDTASGRSV-EHRPNERFPFCSTFKAMLAAAVLAQSV +ERPALLQQRVTYGKADLVNYSPVSGKHVDTGMTVAELCAAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLALGDALPAAQRA +QLVQWLRGNKVGDKRIRAGVPAGWQVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ +ARADARAKDDVIAAVARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFC82A +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRMLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAIS-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI000F59FBBC +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRE +QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDVGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVARTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075F42DC +----GQTLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARSKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F5ACA6B +----GQTLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARSKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075A852B +-----TSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=UPI00075D8726 +---AYDALQALERDAGGRLGVYAVDTASGRSV-EHRPNERFPFCSTFKAMLAAAVLAQSV +ERPALLQQRVTYGKADLVNYSPVSGKHVDTGMTVAELCAAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLALGDALPAAQRA +QLLEWLRGNKVGDKRIRAGVPAGWQVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ +ARADARAKDDVIAAVARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=UPI000841559E +---AYDALQALERDAGGRLGVYAVDTASGRSV-EHRPNERFPFCSTFKAMLAAAVLAQSV +ERPALLQQRVTYGKADLVNYSPVSGKHVDTGMTVAELCAAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLALGDALPAAQRA +QLLEWLRGNKVGDKRIRAGVPAGWQVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ +ARADARAKDDVIAAVARIAVAAf +>[subseq from] Beta-lactamase n=2 Tax=Halomonas muralis TaxID=119000 RepID=A0A1G9S152_9GAMM +---LLEKLVEIEERLDARIGVAVLDIQTGRRW-EYRADERFPMTSTFKALACGAVLARVD +AGQEDLDRRIRIEASDIVTYSPVTENHVGEEMTLGELCKATITTSDNTAGNLILETLDGP +SGVTEFARSLGDSMTRLDRWETELNEATPGDPRDTTTPNAMTANLHKLVLGDTLSQQSRD +QLTTWLVANKTGDEKLRAGLPNDWRVGDKTGGGNHGTTNDVAVIWPPGREPLIVSVYITQ +TKASVDERNAAIADIGRAIH--- +>[subseq from] class A beta-lactamase n=1 Tax=Microvirga massiliensis TaxID=1033741 RepID=UPI00062B5C0E +--DLSREIARIESGLEARLGVAVLDTATGQRM-SHRGSERFPMCSTFKMLACAAVLRRVD +AGQEDLERRIRFGASDVVTYSPVTKDRVGDGMTLAELCEAAMTQSDNTAGNLILKTLGGP +SGVTTFARSLGDLVTRLDRWETDLNEAAPGDPRDTTTPDAMTANLHSLAVDNGLSPQSRD +QLTAWLVANKTGDARLRAGLPKNWRIGDKTGSGERGTANDVAVIWPPQRKPLIVSVYLTE +TKASSDERNAAIAEIGRAV---- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=UPI000754056F +---AYDALQALERDAGGRLGVYAVDTASGRSV-EHRPNERFPFCSTFKAMLAAAVLAQSV +ERPALLQQRVTYGKADLVNYSPVSGKHVDTGMTVAELCAAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLALGDALPAAQRA +QLVQWLRGNKVGDKRIRAGVPAGWQVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ +ARADARAKDDVIAAVARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075D3B85 +----ATSFAALERAAGGRLGVCAIDTASGRHA-RHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075BA194 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGNALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +TRADAKARDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI00098187F9 +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI00075B6A1E +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEATIQYSDNSAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAAARIAVATf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. AU18528 TaxID=2015350 RepID=A0A2G1SC76_9BURK +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV +EQPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRE +QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVARTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F5B275B +-----QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV +GRPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWPPSRAPIAVAVYYTQ +ARADARSQDDVIASVARIVVQAf +>[subseq from] Beta-lactamase n=1 Tax=Rhodopseudomonas palustris TaxID=1076 RepID=A0A323UF44_RHOPL +--ALADRCARLEADSGGRLGVGVLDTASGRIV-GHRLDERFPMCSTFKVLAAGLVLSRVD +RKQESLDRRVSYTKSDLVTYSPATEKHIEGGMTIAELCAAAITLSDNTAANLLLGSFGGP +AGLTAFARSLGDETTRLDRIETELNEALPGDPRDTTSPRAMAQDLRALTLGDTLSPTSRA +QLIAWLKANTTGGTRLRAGVPAGWTVGDKTGTGDRGTANDVAVLWPPQRAPLIVTVYLTG +ATAARDQQSAIIAAVGAAVATKw +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3N9D8P5_9BURK +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAAERFPFCSTFKAMLSAAVLARSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +ARADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI00075A009B +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEATIQYSDNSAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPSAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ +TRADAKAKDDVIAAAARIAVATf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000981E40D +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia multivorans CF2 TaxID=985078 RepID=J4JN58_9BURK +-----ASFAALERAAGGRLGVCAIDAATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDEVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. HAN2018 TaxID=2233539 RepID=UPI000E649071 +-----QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV +ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARSKDDVIASVARIVVQAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=A0A2Z5MZZ9_BURPY +---AAAALADLERDAGGRLGVCAIDTASGRVV-EHRANERFPFCSTFKTMLSAAVLAQSV +ERPGLLQQRVTYGKADLVNYSPVTEKHVGAGMTVAELCAAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTAVPGDLRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVMWPTSRAPIVLVVYYTQ +ARADARAKDDVIASVARIVAQTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A1W0YMY5_9BURK +-----ASFAALERAAGGRLGVCAIDAATGRRA-LHRADERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. NFACC38-1 TaxID=1566268 RepID=A0A1H9YVQ3_9BURK +-----QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV +ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARSKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F5E9EFD +-----QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV +ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARSKDDVIASVARIVVQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075BB301 +-----QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARSKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075CFA54 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWSPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0008913132 +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAILSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. USM B20 TaxID=1571773 RepID=A0A4R9MJE6_9BURK +----ATSFAALERAAGGRLGVCAIDTAGGRRV-QHRADERFPFCSTFKAMLGAAVLAQSV +ERPGLLQQRVDVAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +SAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLMLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAAARIAVAMf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia dolosa TaxID=152500 RepID=A0A345IT63_9BURK +----ATSFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSI +AQPALLQQRVAYGKADLVSYSPVTEQHVGAGMTVAELCAATIQYSDNTAANVLMKLIGGP +QAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRALMLGDALPSAQRA +QFVEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVAWPPSGAPIVLAVYYTQ +ARADARAKDDVIAAAARIAV--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075B6772 +--AAEATFADLERDAGGRLGVCAIDTTSGRII-GHRSGERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNAAANLLMKLLGGP +SAVTAFARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMLGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARSKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007579C92 +-----QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWLPSRVPIAVAVYYTQ +TRADARSKDDVIASVARIVVQAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A103ZRW5_BURCE +--AAEATFADLERDAGGRLGVCAIDTTSGRVI-GHRSGERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNAAANLLMKLLGGP +SAVTAFARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMLGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARSKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075D0CBC +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPGQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI00075AEF6D +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEATIQYSDNSAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPSAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAAARIAVATf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. MSMB1072 TaxID=1637871 RepID=UPI000756D485 +---AATTLADLERDAGGRLGVCAIDTASGRAI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVGALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRALTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TQADARAKDDVIASAARIVARTf +>[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas sp. CF125 TaxID=1855303 RepID=A0A1H1H9J1_9GAMM +---ASGRLQALESLHGGRLGVSILDTGTGKRI-GHRADERFPMCSTFKFLAAAQVLSRVD +RGEERLDRRIVYAKDDLVAYSPVTEKHVATGMTLAELCRATITVSDNTAGNLLLASFGGP +AGLTRFAQSLGDSVTRLDRWETELNEAVPGDPRDTTSPAAMLDDMRSLLLGDTLSPASRK +QLTDWLIATTTGDKRIRGGLPKEWRAGDKTGTSNNGVTNDIAIVWPPGRAPLLVAAYYAE +YAQPKEARNAVIAEVGRIAA--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. BE17 TaxID=2656644 RepID=UPI00128C859B +--AAAAALAELERDAGGRLGVCAIDAASGRRV-EHRADERFPFCSTFKAMLSAAVLAQSV +ARPGLLQQRVTYGKADLVNYSPVTEKHVGAGMTVAELCEATIQYSDNAAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPAAQRA +RLVTWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDVGVVWSPSRAPIVLAVYYTQ +AHADARAKDDVIADVARVVVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI00075CC449 +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEATIQYSDNSAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPSAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAAARIAVATf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI000757EE5F +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEATIQYSDNSAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPSAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAAARIAVATf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=C1J897_9BURK +---AAATLADLERDAGGRLGVCAIDTASGRII-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTVYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI0007689856 +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRE +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVARTf +>[subseq from] Beta-lactamase class A n=1 Tax=Paraburkholderia sp. OV555 TaxID=2135497 RepID=A0A2U0WHG1_9BURK +-qSAASQLKALEAASNGRLGVAALNTADGAIV-NYRADERFPFCSTFKVLLASAILTRSA +HEDGLLDERIRYTQSDLVNYSPVSEKHVADGMTVADLCAAAIQYSDNSAANLLIRLLGGP +SAVTAFARSIGDDEFRLDRTETELNTAIPGDLRDTTTPAAMLRSLQRLALGNALGARERD +QLQAWMRGNTTGDARIRAGVPRDWQVADKTGTGDYGTSNDVAVLWPPSKAPIVVVIYFTQ +REQDAKARSDVLASAAKIVAGKf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D00E009 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPLAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=4 Tax=Burkholderia cepacia complex TaxID=87882 RepID=O08350_BURCE +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAANLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDVGVLWPPSRAPIVLAVYYTQ +TRADAKAKDDVIAAATRIA---- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075A62A8 +----ATSFAALERAAGGRLGVCAIDTASGRQA-WHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFE03F +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGQSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDVGVLWPPSRAPIVLAVYYTQ +TRADAKAKDDVIATATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=UPI0008F4C1E3 +-----QMLAELERSAGGRLGVCAIDIATGRRA-EHRADERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMLGDALPAAQRA +QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ +TRADARAKDDVIASVARIVVRAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F5AE451 +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTRADLVSYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F5AA01F +----GQTLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV +ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ +TRADARSKDDVIASVARIVVQAf +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium erythrophlei TaxID=1437360 RepID=A0A1M5I8Q3_9BRAD +-dNLAKELARLEAESGGRLGVAVLDTSTGAMA-GHRADQPFPMCSTFKVLAVAAILRRVD +AQGEKLERRIGFTKADLVSYSPVTERHLGGDMSLAELCEAAITRSDNTAANLLLANIGGP +ANLTAFVRTLGDQVTRLDRIEPELNEATPGDPRDTTTPNAMLSNLQKLVLGEVLSSASRD +RLTAWMIGNKTGDARLRAGLPAGWRVGDKTGSGARGTANDVAVIWPAERAPVIVAVYLTG +ASGSNDQQNATIAAVARAVS--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A2S9LQS6_9BURK +-----ASFAALERAAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI000CE1C5BC +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV +EQPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRE +QLVTWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVARTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A109EHH5_9BURK +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAAERFPFCSTFKAMLSAAVLARSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +ARADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075BE4BE +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D0067BB +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia contaminans TaxID=488447 RepID=A0A286P6D6_9BURK +-----QVLAELERSAGGRLGVCAIDIATGRRA-EHRADERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRALMLGDALPAAQRA +QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALVVYYTQ +TRADARAKDDVIASVARIVVRAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A088V0N6_9BURK +---AYDALQALEREAGGRLGVYAVDTASGRSV-EHRPNERFPFCSTFKAMLAAAVLAQSV +ERPALLQQRVTYGKADLVNYSPVSGKHVDTGMTVAELCAAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLALGDALPAAQRA +QLLEWLRGNKVGDKRIRAGVLAGWQVGDKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADARAKDDVIAAVARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F59E2C4 +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A2S9M8Z7_9BURK +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFA5EF +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFRFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F5AC330 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVKYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARARDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=UPI00080B0DFA +---AAATFAQLERDAGGRLGVCAIDAASGRRV-EHRADERFPFCSTFKAMLSAAVLAQSV +ARPGLLQQRVTYGKADLVNYSPVTGKHVDTGMTVAELCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDSTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIVLVVYYTQ +AHADARPKEDVIADVARVVVE-- +>[subseq from] ENCA BETA-LACTAMASE n=1 Tax=synthetic construct TaxID=32630 RepID=UPI0002B63CCF +hpQTLEQIKESESQLSGRVGMVELDLASGRTL-SYRADERFPMMSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVEYSPVTEKHLADGMTVAELCAAAITMSDNTAANLLLATIGGP +AGLTAFLRNIGDNVTRLDRWETELNEALPGDERDTTTPAAMAATLRKLLTGEILSAASRQ +QLITWMVADKVAGPLLRSVLPAGWFIADKTGAGERGSRGIIAVLGPDGKPSRIVVIYLTE +TQASMDERNQQIAEIGAALIEHw +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00051017C5 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPEAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia TaxID=32008 RepID=A0A318I1A7_BURPY +--AAAATLAHLERDAGGRLGVCAIDTASGRRV-EHRAAERFPFCSTFKAMLSAAVLAQSV +ARPGLLQQRVTYGKPDLVNYSPVTERHVGAGMTVAELCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLALGDALPAAQRA +QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWAPSRAPIVLAVYYTQ +ARADARAKDDVIADVARVVVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI000752B602 +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFF6BDD +-----ASFAALERAAGGRLGVCAIDAATGRRA-LYRADERFPFCSTIKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDEVIAAATRIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000EF9387A +------------------------------------------------------------ +----------HYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0011CBDCC9 +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQFSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVAAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia (strain MC0-3) TaxID=406425 RepID=B1K831_BURCC +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRMRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI00075D1824 +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075D02CA +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRVPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075DBE4C +----ATSFAALERAAGGRLGVCAIDTASGRQA-WHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRT +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI00075CDA08 +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRE +QLATWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVARTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=A0A0G3WX80_BURPY +---AAATFAQLERDAGGRLGVCAIDAASGRRV-EHRADERFPFCSTFKAMLSAAVLAQSV +ARPGLLQQRVTYGKADLVNYSPVTGKHVDTGMTVAELCEATIQYSDNAAANLLMKLIGGP +SAVTAYARSIGDSTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIVLVVYYTQ +AHADARPKEDVIADVARVVVE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. BE12 TaxID=2082394 RepID=UPI000CF47F45 +---AAATIADLERDAGGRLGVCAIDTASGRAI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSGKHVGTGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDMFRLDRWEPELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA +QLVTWLRGNKVGDKRIRAGVPTGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia complex TaxID=87882 RepID=UPI00075956FD +---AATTLADLERDAGGRLGVCAIDTASGRAI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVGALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRALTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +AQADARAKDDVIASVARIVARTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0003F9130F +---AAATLADLERDAGGRLGVCAIDAASGRAI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGTGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPSAQRA +QLITWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0011ABBE23 +----GQTLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ +ARADARSKDDVIASVARIVVQAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=C1J8A0_9BURK +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI00075456EF +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEATIQYSDNSAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDHGTTNDAGVIWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAAARIAVATf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075C42E3 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0009E0F836 +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia multivorans CGD2 TaxID=513052 RepID=B9BS30_9BURK +-----ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDVGVMWPPSRAPIVLAVYYTQ +TRADAKAKDDVIATATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0009E0DC2B +-----ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDVGVMWPPSRAPIVLAVYYTQ +TRADAKAKDDVIATATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D004034 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +TRADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007529BB0 +-----QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV +ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ +TRADARSKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F60014C +-----QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV +ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ +TRADARSKDDVIASVARIVVQAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia dolosa AU0158 TaxID=350701 RepID=A2WFY8_9BURK +----ATSFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSI +AQPALLQQRVAYGKADLVSYSPVTEQHVGAGMTVAELCAATIQYSDNTAANVLMKLIGGP +QAVTAYARSIGDATFRLDRWETELNTALPGDPRDTTTPAAMAASLRALMLGDALPSAQRA +QFVEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVAWPPSGAPIVLAVYYTQ +ARADARAKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. AU28863 TaxID=2015352 RepID=UPI000B79F216 +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRASERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +ARADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0008416FCA +----ATSFAALERAAGGRLGVCAIDTASGRHA-RHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia reimsis TaxID=2234132 RepID=A0A365QZ51_9BURK +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000754EE01 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000277CA0F +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDVGVLWPPSRAPIVLAVYYTQ +TRADAKAKDDVIATATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFE6CDA +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRT +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D002920 +-----ASLAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRT +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. AU17457 TaxID=2015349 RepID=UPI000B79F483 +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRASERFPFCSTFKAMLSATVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDVGVIWPTSRAPIVLAVYYTQ +ARADARAKDDVIASVARIVAQTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. LA-2-3-30-S1-D2 TaxID=1637862 RepID=A0A1B4ETC7_9BURK +----ATSFAALERAAGGRLGVCAIDTASGRHA-RHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLQQRVTIAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPDAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVATf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. HI2761 TaxID=2015360 RepID=A0A228QA03_9BURK +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGTGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA +QLVTWLRGNKVGDKRIRAGVPTGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F5B5EBD +---AAAMLADLERDAGGRLGVCAIDTASGRVI-EHRAAERFPFCSTFKAMLSAAVLARSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +ARADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0006AC9657 +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAILSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +ARADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F594E81 +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAAERFPFCSTFKAMLSAAVLARSV +ERPGLLQQRVTYTKADLVNYSPVSGKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +ARADARAKDDVIASVARIVAQTf +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A1V2XBA9_9BURK +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI00078BCEFD +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=UPI00075C46CE +---AYDALQALERDAGGRLGVYAVDTASGRSV-EHRPNERFPFCSTFKAMLAAAVLAQSV +ERPALLQQRVTYGKADLVNYSPVSGKHVDTGMTVAELCAAAIQYSDNSAANLLMKLIGGP +LAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLALGDALPAAQRA +QLVEWLRGNKVGDKRIRAGVPAGWQVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ +ARADARAKDDVIAAVARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. CCA53 TaxID=1776288 RepID=UPI00080B1005 +-----ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +TRADAKAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=A0A104LDA2_9BURK +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV +EQPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRE +QLVAWLRCNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVARTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075BC7C7 +----GQMLAELESSLGGRLGVCAIDTASGRVI-THRADERFPFCSTFKAMLSAAVLAQSV +ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ +ARADARSKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075F4877 +-----EMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000981D5D7 +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGGYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3N8ZSQ1_9BURK +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRASERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLTLGDALPAAQRA +QFVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDVGVIWPTSRAPIVLAVYYTQ +ARADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFB513 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +TRADAKAKDDVIATATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000753509D +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARSKDDVIASVARIVVQAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. ABCPW 11 TaxID=1637859 RepID=A0A103B6S2_9BURK +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVGALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRALTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +AQADARAKDDVIASAARIVARTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D3338AF +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGAYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A107PQ27_BURCE +----GQMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARIVVHAf +>[subseq from] PenA family class A beta-lactamase n=2 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0002344058 +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVTQTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. AU6039 TaxID=2015344 RepID=A0A228PHG2_9BURK +-----QMLAELERSAGGRLGVCAIDIATGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYTRADLVNYSPVSGKHVDDGMTVAALCEATIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGEALPAAQRA +QLVAWMRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSGAPIALAVYYTQ +ARADARAKDDVIASVARIVVRAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F599506 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007580E34 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000759EE17 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000751FEB7 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARSKDDVIASVARIVIQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F564DF1 +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVAYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMATSLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=B8R6A5_9BURK +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVKYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000484E52E +----AATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV +ERPGLLQQRVTYTRADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas duriflava TaxID=459528 RepID=A0A562QL37_9PSED +--ATEQRLARLEQELNGRLGVFAWDTGAGTVL-RYRADERFPMNSTFKVMLAAAILAQNE +KAHGLLEQHIRYTEHDLVTYSPITEKHLAQGMTIAELCAAAIQYSDNTAANLLMAHLGGP +AAVTAFARSIDDEMFRLDRWETELNTAIPGDPRDTSTPEAMGYSLQRLALGDALSAASRE +QLQAWLRGNTTGNTRIRAGVPSDWQVGDKTGTGDYGTASDIAVLWPPGRAPMIIAIYTAQ +TEPTAKARNDVIASAARVVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000C9B0EE5 +---LTQRFAELEKQLDARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD +AGADSLQTRIRYTADDLVTYSPVTERHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP +GAIGDFARTLGDHHTRLDRWETELNEASPGDPRDTTTPAAMAANLQRLVLGDSLSAASRE +QLVAWMLASQTGAAKLRAGLPPGWRIGDKTGSGERGTTNEVAVIWPPQRKPVIACVYLTQ +TQASADARNAALAAIGRALAE-- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia TaxID=32008 RepID=A0A4S3HX95_BURCE +-----QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ +ARADARSKDDVIASVARIVVQAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp9004 TaxID=2184559 RepID=A0A3P0SIV7_9BURK +----ATSFAALERAAGGRLGVCAIDTASGRHA-RHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLQQRVTIAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPDAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIALATf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0007542FCB +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFF9303 +-----ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +TRADAKAKDDVIATATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A5P2K0U9_9BURK +-----ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +TRADAKAKDDVIATATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000841C7DB +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVMWPPSRAPIVLAVYYTQ +TRADAKAKDDVIATATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008418F4E +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALLTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDEAFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +AHADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. SRS-25 TaxID=2094190 RepID=A0A4R4C1P1_9BURK +---AAQMLAELERSAGGRLGVCAIDIATGRRA-EHRAEERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMLGDALPAAQRA +QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ +TRADARAKDDVIASVARIVVRAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007558954 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARSKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. MSMB1826 TaxID=1637875 RepID=UPI000751FFF9 +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVARTf +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A1V2VWQ1_9BURK +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFE5840 +-----ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDRRIRAGVPTGWRVGDKTGTGDYGTTNDVGVLWPPSRAPIVLAVYYTQ +TRADAKAKDDVIATATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075FAEB1 +----ATSFAALERAAGGRLGVCAIDTASGRQA-WHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F596C46 +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAAYYTQ +TRADARAKDDMIASVARIVAQTf +>[subseq from] Beta-lactamase enzyme family n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A5P8VE29_BURCE +-----QMLAELESSVGGRLGVCAIDTASGRVI-THRADERFPFCSTFKAMLSAAVLAQSV +ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMELLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ +ARADARSKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000752C178 +-----ASFAALERAAGGRLGVCAIDTGTGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPEAMAASVRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +TRADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000665F193 +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVTQTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. AU16741 TaxID=2015347 RepID=A0A228HKA1_9BURK +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV +ERPGLLQQRVTYTKADLVNYSPVSERHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +PAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDVGVIWPTSRAPIVLAVYYTQ +ARADARAKDDVIASVARIVAQTf +>[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas palustris TaxID=1076 RepID=UPI000E5AECEA +--ALADMCARLEAGSGGRLGVGVLDTASGRMI-GHRLDERFPMCSTFKVLAAGLVLARVD +RKQEKLDRRVSYAKADLVTYSPATEKHVEDGMTIAELCKAAITLSDNTAANLLLASFGGP +AGLTAFARSLGDETTRLDRIETELNEALPGDPRDTTSPRAMAQDLRALTLGDALSPASRA +QLITWLKANTTGGTRLRAGVPPGWTVGDKTGTGGRGTANDIAVLWPPQRTPLIVTVYLTG +ATVVRDQQNKIIADVGAAVAD-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=UPI000F59A2C7 +---AAQMLAELERSVGGRLGVCAIDIATGRRA-EHRAEERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMLGDALPAAQRA +QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ +TRADARAKDDVIASVARIVVRAf +>[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. YR577 TaxID=1884373 RepID=A0A1I7EDY1_9RHIZ +--DAAAQLRALEKKYGGRLGVAILDTASGTRI-EHRADERFALCSTFKVLASAAVLARVD +KGEEKLDRRITYEKKDLVTYSPVTEKHVGKKMTLAELCEAAITLSDNTAGNLLLASFGGP +AGLTAYARTLGDEVTRLDRIETALNEAKTGDPRDTTTPAAMLADLQKLVLGDALSPASRD +QLKTWLLANKTGDKRLRAHLPKDWKVGDKTGTGDNGSANDVGILWPPKRGPIIVSSYFTE +SSASTDEKNIVHAEVGRIAA--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI00084673D7 +---AAATLADLERDAGGRLGVCAIDTASGRDI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A4Q2AEF3_9BURK +-----TSFDALERAAGGRLGVCAIDTASGRRA-LYRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYGKADLVKYSPVSEKHVDTGMTVADLCAAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLTLGEALPAAQRA +QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWPPSRAPIVLTVYYTQ +TRADARAKEDVIAAATRIAVATf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000CFFA38B +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVKYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A498RWF3_9BURK +----AAALADLERDAGGRLGVCAIDTASGRSV-EHRPNERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYSKADLVNYSPVTEKHVDTGMTVAAMCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPAAQRA +QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ +AQADARSKDDVIASAARIVARAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia TaxID=32008 RepID=UPI00064F0B97 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYTRSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000759AFC1 +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAEWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI00048637BA +---AATTLADLERDAGGRLGVCAIDTVSGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDEAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +ARADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075C4E24 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +TRADAKAKDDVIATATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI00075F0500 +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV +EQPGLLQQRVTYTKADLVNYSPVSEKHVGAAMTVAALCEATIQYSDNSAANLLMKLVGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRE +QLVTWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVARTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A095EC36_BURCE +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAEWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D004F65 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELKTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F56F5CB +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTRANLVSYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0008417161 +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSGKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +ARADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007B7E3C8 +----ATSFAALERAAGGRLGVCAIDTASGRHA-RHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRICAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVATf +>[subseq from] class A beta-lactamase n=1 Tax=Acidobacteriaceae bacterium KBS 89 TaxID=1267534 RepID=UPI00035F7867 +-dQLNRELEKIEAASGGRLGVAILDTATGARI-LHRGDERFPMCSTFKLVACAAVLAKVD +AGKQRLDQRIIFQKTDLVTYSPITQTHTGAPMTLGEICAAAIDYSDNTAANLILDNLGGP +AGFTQFARSIGDPVTRLDRIETALNESLPNDPRDTTTPSAMVTNLNSLLLGSALSPPSRD +QLTQWLLANTTGGTRLRAGVPATWRVGDKTGTGDQGSTNDIGILWPPNAKPILVCVYLTG +TKASADERNATIASVGRAVAA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F5A3E13 +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAAERFPFCSTFKAMLSAAVLARSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTAPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +ARADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. AU31280 TaxID=2015353 RepID=UPI000B7A20FB +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAAERFPFCSTFKAMLSAAVLARSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAHARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +ARADARAKDDVIASVARIVAQTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A095DJB8_BURCE +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV +ERPGLLQQRVTYTQADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVARTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A1V6L286_9BURK +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVKYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRTPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia JBK9 TaxID=1395570 RepID=A0A0U4CD75_BURCE +----VAAFADLERNAGGRLGVCAIDTASGRRI-EHRSGERFPFCSTFKAMLSAAVLAQSV +DRPGLLQQRVTYTRADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGEALPAAQRA +QLVTWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPASRAPIVLVVYYTQ +TQADARAKDDVIASVARIVAQTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A3P0WRM2_BURCE +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTFTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFE9097 +-----ASFAALERAAGGRLGVCAIDAATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0003C47E21 +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAALLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAAYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. AU31652 TaxID=2015354 RepID=UPI000B79D645 +-----QMLAELERSAGGRLGVCAIDIATGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTQADLVNYSPVSGKHVDDGMTVAALCEATIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGEALPAAQRA +QLVAWMRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSGAPIALAVYYTQ +ARADARAKDDVIASVARIVVRAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000980ED6A +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNLAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVTQTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. FL-7-2-10-S1-D7 TaxID=1637866 RepID=A0A103L2Y5_9BURK +----ATSFAALERAAGGRLGVCAIDTASGRLA-RHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLQQRVTIAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPDAMAASMRVLTLGEALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVATf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0009E0E129 +-----ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +TRADAKAKDDVIATATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. NRF60-BP8 TaxID=1637853 RepID=UPI00075C3F3B +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASAARIVARTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A2X1GQN3_BURCE +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARILVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000751F368 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARILVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075BCEE6 +----ASSLAELERAAGGRLGVHVLDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI00124683C5 +----ATSFAALERAAGGRLGVCAIDTASGRHA-RHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLQQRVTIAQSDLVNYSPVSGKHVSTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPDAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVATf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000C9C0815 +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNLAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGGYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVTQTf +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000EF7B767 +-----------------RVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000759A109 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSREPIAVAVYYTQ +ARADARAKDDVIASVARILVQAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia seminalis TaxID=488731 RepID=A0A103KF24_9BURK +---AAAALADLERDAGGRLGVCAIDTASGRVI-AHRPDERFPFCSTFKAMLSAAVLAQSV +DRPGWLQQRVTYTKADLVNYSPVSGKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAEQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ +AQADARAKDGVIASVAQIVARTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. 28_3 TaxID=2183921 RepID=A0A364GRC7_9BURK +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVKYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI00078B40E7 +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAFTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVTQTf +>[subseq from] Beta-lactamase n=1 Tax=Rhodopseudomonas palustris (strain TIE-1) TaxID=395960 RepID=B3Q9A2_RHOPT +--ALADMCARLEAGSGGRLGVGVLDTASGRMI-GHRLDERFPMCSTFKVLAAGLVLARVD +RKQEKLDRRVSYAKSNLVTYSPATEKHVEDGMTIAELCEAAITLSDNTAANLLLASFGGP +AGLTAFARSLGDETTRLDRIETELNEALPGDPRDTTSPRAMAQDLRALTLGDALSPASRA +QLITWLKANTTGGTRLRAGVPPGWTVGDKTGTGSRGTANDIAVLWPPQRAPLIVTVYLTG +ATVVRDQQNKIIADVGAAVAD-- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A1D7ZLC0_9BURK +----AAALADLERDAGGRLGVCAIDTASGRIV-EHRPNERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYSKADLVNYSPVTEKHVDTGMTVAAMCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPAAQRA +QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ +AQADARSKDDVIASAARIVARAf +>[subseq from] Beta-lactamase n=1 Tax=Caballeronia telluris TaxID=326475 RepID=A0A158IF65_9BURK +-qSAASQLKALEAASNGRLGVAALNTGDGAIV-NYRADERFPFCSTFKVLLASAILTRST +HEDGLLDQRIRYTQSDLVNYSPVSEKHVADGMTVAELCAAAIQYSDNSAANLLIRLLGGS +SAVTAFARSIGDDEFRLDRTETELNTAIPGDLRDTTTPAAMLRSLKRLALGDALGARERD +QLQAWMRGNTTGDARIRAGVPLDWQVADKTGTGDYGTSNDVAVLWPPSKAPIVVVIYFTQ +REQDAKARNDVLASAAKIVAGKf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3N9FPW0_9BURK +---AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTRADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQ-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007574A9F +----ASSLAELERTAGGRLGVHVLDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=A0A105VSS3_9BURK +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVPIAQSDLVNYSPVSGKRVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVARf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A3N7PT91_9BURK +-----TSLTELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALLTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCAATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. HI2500 TaxID=2015358 RepID=UPI000B7A6289 +-----QMLAELERSAGGRLGVCAIDIASGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEATIQFSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGEALPAAQRA +QLVAWMRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSGAPIALAVYYTQ +ARADARAKDDVIASVARIVVRAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. D-99 TaxID=2717316 RepID=UPI001424218F +-----QMLAELESSVGGRLGVCAIDIASGRVV-EHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVDEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASVRVLMLGDALPAAQRA +QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARIVVQ-- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia TaxID=32008 RepID=A0A2S5E6M4_9BURK +-----QMLAELERSAGGRLGVCAIDIATGRRA-EHRADERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMASSMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWTPSGAPIALAVYYTQ +ARADARAKDDVIASAARIVVRAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A119M6D0_9BURK +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALLTQRVTYRQADLPEWSPVTEKHVDTGMTVDELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +AHADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia seminalis TaxID=488731 RepID=UPI000F5A1168 +---AAAALADLERDAGGRLGVCAIDTASGRVI-AHRPDERFPFCSTFKAMLSAAVLAQSV +DRPGWLQQRVTYTKADLVNYSPVSGKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ +AQADARAKDGVIASVAQIVARTf +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia cepacia TaxID=292 RepID=A0A1Z3Z1E8_BURCE +-----QMLAELESSVGGRLGVCAIDTASGRII-EHRADERFPFCSTFKAMLSAAVLAQSV +GRPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ +TRADARSKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075AEE21 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075C6714 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F5EAD20 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSREPIAVAVYYTQ +ARADARAKDDVIASVARILVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D1EBD +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPEPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A0J5X269_BURCE +-----TSFDALERAAGGRLGVCAIDTASGRRA-LYRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYGKADLVKYSPVSEKHVDTGMTVADLCAAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWPPSRAPIVLTVYYTQ +TRADARAKEDVIAAATRIAVATf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A104TUA0_9BURK +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007568858 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLLGNKTGDKRIRAGVPKGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007546CA6 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARILVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFC6A7 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPLAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075C52CA +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia seminalis TaxID=488731 RepID=UPI00066611A5 +----AAALADLERDAGGRLGVCAIDTASGRVI-AHRPDERFPFCSTFKAMLSAAVLAQSV +DRPGWLQQRVTYTKADLVNYSPVSGKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ +AQADARAKDGVIASVAQIVARTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000755ECD6 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQHA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007530F3C +----ASSLAELERAAGGRLGVHVLDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATARYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000981E96F +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTVLPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754E1B7 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDVRDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B8320 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075BE8E6 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075A9809 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPGGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007551BAE +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B2224 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=UPI0006256D8D +---AAQMLAELERSAGGRLGVCAIDIATGRRA-EHRAEERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ +TRADARAKDDVIASVARIVVRAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. MSMB1835 TaxID=1637876 RepID=A0A104CLD7_9BURK +----ATMLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ +TRADARAKDDVIASVARIVARTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754A9DF +----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=A0A3N8QH59_9BURK +---AAQMLAELERSVGGRLGVCAIDIATGRRA-EHRAEERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMLGDALPAAQRA +QLVTWMCGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ +TRADARAKDDVIASVARIVVRAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A119UZC5_9BURK +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007594A10 +----ASSLAELERAAGGRLGVHVLDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000667E7C6 +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKLGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVTQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000760749A +----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075502FE +----ATSFAELERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTSPAAMAASMRVLTLGDALPPVQCA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007551A4B +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDVGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075EBA14 +----ASSLAELERAAGGRLGVHALDTATGRHV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007541252 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKREDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D000495 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPTAWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075FBE38 +----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000752C89F +----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWEVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=A0A2S9NIW3_9BURK +-----QVLAELERSAGGRLGVCAIDIATGRRA-EHRTDERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPDDPRDTTTPAAMAASMRVLMLGDALPAAQRA +QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ +TRADARAKDDVIASVARIVVRAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000757259D +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLALGDALPAPQRA +QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPAGRPVALAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D00DD56 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRT +QLIEWLRGNKVGDKRIRAGVPTAWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia seminalis TaxID=488731 RepID=UPI00084F61AB +--AAAAALADLERDAGGRLGVCAIDTASGRVI-AHRPDERFPFCSTFKAMLSAAVLAQSV +DRPGWLQQRVTYTKADLVNYSPVSGKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ +AQADARAKDGVIASVAQIVARTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F0E0D +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFAQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007529B65 +----ASSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F8A55 +----ASSLAELERATGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLGWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWEVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075BBE5D +----ASSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0013F46BA1 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLRQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPSDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075397B4 +----ATSLAELERAAGGRLGVYALDTATGRRV-QHRADERFPFCSTFKAVLIAAVLAQSA +ARPALLARHVMYRQADLVGWSPVTEKHVDAGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QYVQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKGRDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A108CUI1_9BURK +----ATSLAELERAAGGRLGVYALDTATGRRV-QHRADERFPFCSTFKAVLIAAVLAQSA +ARPALLARHVMYRQADLVGWSPVTEKHVDAGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QYVQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKGRDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=C1J899_9BURK +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTVYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D00AF05 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LYRAGERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETEPNTALPGDLRDTTTPEAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. HI2714 TaxID=2015359 RepID=A0A228QUB7_9BURK +-----QMLAELERSAGGRLGVCAIDIASGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEATIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGEALPAAQRA +QLVAWMRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPVALAVYYTQ +ARADARAKDDVIASVARIVVRAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007583503 +----ATSLAELERAAGGRLGVYALDTATGRRV-QHRADERFPFCSTFKAVLIAAVLAQSA +ARPALLARHVMYRQADLVGWSPVTEKHVDAGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QYVQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKGRDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0005D785D7 +----ASSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000DC5441C +-----QMLAELESSVGGRLGVCAIDTASGRVI-THRADERFPFCSTFKAMLSAAVLAQSV +GRPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ +ARADARSKDDVIASVARIVVQAf +>[subseq from] Beta-lactamase n=1 Tax=Halomonas anticariensis (strain DSM 16096 / FP35) TaxID=1121939 RepID=S2KQ94_HALAF +-dELSRKLTEIEERLRARMGIAILDTETQRQW-TQRADERFPMCSTFKLLASAAVLTRVD +AGQEDLNRRIRFEASDVVTYSPVTEHRVGGEMTLAELCEAALTMSDNTAGNILLESLGGP +SGVTEFARSLGDSMTRLDRWETELNEAIPGDPRDTTTPAAMTANLRSLILGDRLSQTSRD +QLTTWLVSNKTGDARLRAGLPTNWRIGDKTGGGEYGTTNDVAVIWPPSRKPLIVSVYITE +TEASFDDRNAAIADVGRAV---- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075E8C87 +----ATSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075CF839 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRT +QLIEWLRGNKVGDKRIRAGVPTAWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas sp. EAR18 TaxID=2518972 RepID=UPI00109CCD6D +---FGERLADLESRLDARIGVAVLDTQTGLRW-GYRADERFPMSSTFKVLACGAVLARVD +AGKESLDRRLRFEAGDLVTYSPVTEHRTGGEMTLAELCEATITTSDNTAGNLILGTLGGP +AGLTDFMRTLGDDATRLDRWETALNEATPGDPRDTTTPRAMTDSLHALLLGDRLSPSSRE +RLIDWLVANQTGDAKLRAGLPEGWRIGDKTGGGGHGTNNDVAIIWPPGRQPAIVSVYLTG +SQADFEARNAAIADVARAL---- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp8992 TaxID=2184554 RepID=A0A3N8I6T0_9BURK +-----AALADLERDAGGRLGVYAIDTARGRVV-EHRSGERFPFCSTFKAMLSAAVLAQSV +DRPGLLQQHVTYTQADLVNYSPVSGKHVGTGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAFARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGEALPAAQRA +QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ +AQADARAKDDVIASVARIVAQTf +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. CI-41S TaxID=2511167 RepID=UPI0010B437D7 +-qRLQQAFSRIEQDTGGRLGIAALDTESGLRA-SLRGDERFPMCSTFKALASAAVLRRVD +RGESSLDQRVRFEAKDILANSPVTKEHVASGMTLAELCEAAITRSDNTAGNMLLREIGGP +EGLTSFFRAIGDNVSRLDRWELALNEAVPGDPRDTTSPTAMLKNLQRVLLGDALSATSRK +TLTDWMVANKTGDARLRAGVPADWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ATAPADKCNEAIASVARAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. Chol1 TaxID=440512 RepID=K5YH17_9PSED +---LTQRFAELEKQLDARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD +AGADSLQTRIRYSADDLVTYSPVTERHVNDGMTLAALCEAAITLSDNTAGNLLLRHLGGP +GAIGDFTRTLGDRHTRLDRWETELNEASPGDPRDTTTPAAMAANLQRLVLGDSLSAASRD +QLIGWMLASQTGAAKLRAGLPQGWRIGDKTGSGERGTTNEIAVIWPPQRKPLIACVYLTQ +TQASADARNAALAAIGRALAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rugamonas sp. FT29W TaxID=2660639 RepID=A0A6A7N753_9GAMM +-----ALLAKLEAESGGRLGVAALNTADGRRL-LHRADERFPFCSTFKMMLSAAVLAREP +---ALLKKRVAYRKSDLVAYSPITEQHVGKGMTVAALCEATIQYSDNAAANLLMKQIGGP +AAVTAFARSIGDTEFRLDRIETELNTALPGDPRDTTTPEAMAESLNKLVLGDALGAAQRK +QLKDWMLGNTTGDTRIRAGVPAGWQVADKTGTGDYGTTNDIGVIWQPGKAPIVLVVYLTQ +PGKDDKARSEILAEASKIVVEAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D89A2 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRT +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0013E03BC8 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFYSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPLAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. BJB412 TaxID=1871178 RepID=UPI000C1039BF +--TAEARLAALESGWGGRLGVFAIDTANERGI-GFRAGERFAFCSTFKVMLATAVLERSK +QAPELLQQRIKYAKSELVNYSPITEDHVDDGMSVAELCAAAIQYSDNTAANLLIKLLGGT +AAVTAYARAIGDQEFRLDRWETELNTAIPGDPRDTTTPAAMGRSLRRLAVGDALPAPLRA +QLQDWMRGNTTGDARIRAGVPAGWQVGDKTGTGDYASANDIGVVWPPQRAPIVLAVYTAQ +ADKDAKANSEVIAAATRIVLEH- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=UPI000F5832FE +---AAQMLAELERSVGGRLGVCASDIATGRRA-EHRAEERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMLGDALPAAQRA +QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ +TRADARAKDDVIASVARIVVRAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE6543 +----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLKWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWEVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE1133 +----ASSLAELERTAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A119LN97_9BURK +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMVASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D3A17 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKGKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754EF12 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +TRPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758E6C9 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKGKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) TaxID=482957 RepID=A0A3G3HBY0_BURL3 +---AAATFARLEHDAGGRLGVCAIDTASGRRL-VHRADERFPFCSTFKAMLSAAVLAQSI +KRPALLQQRVTYTKADLVKYSPVSEKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDRAFRLDRWETELNTALPGDQRDTTTPAAMAASMRALMVGDALPAAQRA +QLVTWMRGNKVGGKRIRAGVPAGWTVADKTGTGDYGTTNDAGVVWSPSRAPIVLVVYYTQ +ASADASAKDDVIAGVASVVATAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI001326A505 +----ATSFEALERAAGGRLGVCAIDTGTGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEKHVGAGMTVGELCEATAQYSDNSAANLLMKLLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDARDTTTPAAMAASLRVLALGDALPAPQRA +QFVTWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVTLAVYYTQ +AHADAQAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000752F28D +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTRRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMVASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759B14E +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKGKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075E70B9 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +TRPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. MSMB617WGS TaxID=1637831 RepID=A0A1B4SHA2_9BURK +--AAERQLRELESTFDGRLGFVALDTATGTRI-AYRADERFPFCSTFKTMLSAAILARSA +GDAELLQRRVRYTKRDLVNYSPITEKHVGKGMTIAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDTTFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGAAQRA +QLDAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTGNDIGVAYPPNRAPIVFVVYTTM +REKNAQARSDVIASAARIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp9012 TaxID=2184562 RepID=A0A3N8E6L5_9BURK +----ATSFAALERAAGGRLGVCAIDTASGRHA-RHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLQQRVTIAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDMTTPDAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIALATf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075E33F5 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAATTRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp8963 TaxID=2184547 RepID=A0A3N8LA60_9BURK +------SLASLERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKALLSAAVLAQSV +ERPALLQQRVAYRQADLVRYSPVTERHVGAGMTVAELCAAAVQYSDNSAANLLLKLIGGP +AALTAFARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMSASLRVLALGDALPASQRA +QLADWLRGNRTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDAGVLWPPARGPVVLTVYYTQ +AQADAKAKDDVIASATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007566D6D +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAATTRIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI0013F4F6E8 +---LTQRFAELEKQLDARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD +AGADSLQTRIRYTADDLVTYSPVTERHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP +GAIGDFARTLGDHHTRLDRWETELNEASPGDPRDTTTPAAMAANLQRLVLGDSLSAASRE +QLVAWMLASQTGAAKLRAGLPPGWRIGDKTGPGERGTTNEVAVIWPPQRKPVIACVYLTQ +TQASADARNAALAAIGRALAE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007581EA7 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLLGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=UPI000F56903F +-----QMLAELERSAGGRLGVCAIDVATGRRA-EHRAEERFPFCSTFKAMLSAAVLAQSV +DRPALLQKRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMLGDALPAAQRA +QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ +TRADARAKDDVIASVARIVVRAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FFFA89 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTRRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMVASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia puraquae TaxID=1904757 RepID=A0A1X1PKW2_9BURK +--AAEAALADLERDAGGRLGVCAIDTARGRIV-EHRSSERFPFCSTFKAMLSAAVLAQSV +DRPGLLQQHVTYTQADLVNYSPVSGKHVGTGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAFARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGEALPAAQRA +QLVSWLRGNKVGDKRIRAGVPAGWKVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ +MQADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000751CE3E +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTRRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMVASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A107KA39_9BURK +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLLGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0002EB9F67 +----ATSLAELERAAGGRLGVYALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALLTQRVTYRQADLPEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDNTFRLDRWETELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTRWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A105YNW7_9BURK +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRHADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F5A5172 +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKTMLSAAVLAQSV +ERPGLLQQRVKYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +RLVAWLRGNKVGDKRIRAGVPAEWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia oklahomensis TaxID=342113 RepID=UPI00016A3D03 +--AAERQLSELESSFGGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAILARSA +GDATLLQRRIPYAKRDLVSYSPVTEKHVGDGMTVAELCAAALQYSDNTAANLLIALLGGP +QAVTAYARSIGDTTFRLDRRETELNTAIPGDERDTTTPAAMAASLRRLLVGDALGAAQRA +QLDTWMLGNTTGAARIRAGVPADWRVADKTGTGDYGTGNDIGVAYPPNRAPIVIVIYTTM +RDKNAQARNDVLASAARIAARTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI000758DA73 +----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTIAQSDLVSYSPVSGKHVGVGMTVAELCEAEIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIASAARIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075C4B5D +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKYVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARILVQAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp9143 TaxID=2184574 RepID=A0A3N7ZYD0_9BURK +----ATSFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTVAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +AAVTAYARSIGDDAFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPRSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007598E4B +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMVASLRALALGNALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWEVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia catarinensis TaxID=1108140 RepID=A0A1J9PAI1_9BURK +----------SERDAGGRLGVCAIDTASGRSV-EHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQRRVTYGKADLVNYSPVTEKHVGAGMTVAGLCEATIQYSDNSAANLLIKLIGGP +PAVTAYARSIGDDRFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGEALPAAQRA +QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGIVWPPSRAPIVLVVYYTQ +AQADARAKDDVIASAARIAVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000752D2B3 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRLETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARIVVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075E3F05 +----ASSLAELERATGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADVKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D0188ED +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPHAQRA +QLIEWLRGNKVGDKRIRAGVPTAWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075220F3 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEQHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAATTRIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium macuxiense TaxID=1755647 RepID=UPI0011BFA7EA +-qRLQQEFARIELATTGRLGVAALDMETGLRA-SQRGDERFPMCSTFKAMLSAAVLHRVD +RGESSLDQRMQVEAKDILAYAPVAKQHVGSGMTLAELCEAAITLSDNTAANLLLREIGGP +AGLTSFFRSVGDNVSRLDRWEVELNEAMPGDPRDTTSPVAMLKDLQRVVLGDALQANSRQ +RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVAVYLTG +ASAPMEKCNEVIANVARAVAN-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000753B635 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRAEERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D37C8 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B32CA +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAVATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI000B7A629B +-----QMLAELERSAGGRLGVCAIDIATGRRA-EHRADERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYTKADLVNYSPVSGKHVEDGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ +ARADARAKDDVIASAARIVVRAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D0089C8 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LYRAGERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDSTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPEAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp8998 TaxID=2184557 RepID=A0A3N8GT26_9BURK +-----TSFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLSAAVLAQSV +ARPGLLQQRVTVAQSDLVNYSPVSGKHVGTGMTVGELCEAAIQYSDNSAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPRSRAPIVLVVYYTQ +ARADAKAKDDVIAATARIAVAMf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000755B4E6 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDRRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARANAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium macuxiense TaxID=1755647 RepID=A0A560M4X3_9BRAD +-qRLQQEFARIELATTGRLGVAALDMETGLRA-SQRGDERFPMCSTFKAMLSAAVLHRVD +RGESSLDQRMQVEAKDILAYAPVAKQHVGSGMTLAELCEAAITLSDNTAANLLLREIGGP +AGLTSFFRSVGDNVSRLDRWEVELNEAMPGDPRDTTSPVAMLKDLQRVVLGDALQANSRQ +RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVAVYLTG +ASAPMEKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. MSh2 TaxID=1506588 RepID=A0A084DC39_9BURK +---AAQLLADLERDAGGRLGVCAIDVASGRQA-AYRADERFPFCSTFKTLLSGAVLAQSV +ERPALLQQRVTYGKADLVNYSPVTEQHVGTGMTVAALCEAALQHSDNSAANLLMKLLGGP +SAVTAYARSIGDDVFRLDRWETELNTALPGDLRDTTTPAAMVASVRALMLGDALPAAQRA +QLVAWMRGNQVGGKRFRAGVPAGWTVADKTGTGDYGTTNDVGVVWSPSRAPVVLVVYYTQ +AGADARPKEDVIASAARIVIQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B34D7 +----ASSLAELERAAGGRLGVHVLDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKRVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075E9D4F +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADVKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007578982 +----ATSLAELERAAGGRLGVHALDTVTGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A071MA41_9BURK +---AAAALADLERDAGGRLGVCAIDTASGRVI-AHRPDERFPFCSTFKAMLSAVVLAQSV +DRPGWLQQRVTYTKADLVNYSPVSGKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAEQRA +QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ +AQADARAKDGVIASVAQIVARTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00057F6F42 +-----ASFAALERAAGGRLGVCAIDAATGRRA-LHRADERFPFCSTFKAMLAAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERYVDTGMAVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATQIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A658CYX0_9BURK +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVHYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075F9860 +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLALGDALPAPQRA +QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFAA24 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLRQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +RLIEWLRGNKVGDKRIRAGVPTAWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0007593895 +-----ASFAALERAAGGRLGVCAIDTATSRRA-LHRGDERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA +QLIEWLRGNKVGDKRIRAGVPTAWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI0014202DD9 +---TYDALAALERSAGGRLGVCAIDIASGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVMYTKADLVNYSPVSGKHVDDGMTVAALCEATIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGEALPAAQRA +QLVAWMRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPVALAVYYTQ +ARADARAKDDVIASVARIVVRAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia TaxID=32008 RepID=UPI000B7A1838 +----GQTLVELERSAGGRLGVCAIDIATGRRA-EHRADERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARTIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWTPSGAPIALAVYYTQ +ARADARAKDDVIASAARIVVRAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) TaxID=482957 RepID=Q399I5_BURL3 +-----DALAVLERSAGGRLGVCAIDIASGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLIKLLGGP +SAVTAYARSIGDDTFRLDRWETELNDAVPGDPRDTTTPAAMAASLNALMLGGALPAAQRA +QLVAWMRGNKVGDKRIRAGVPAGWTVADKTGTGDYGTTNDAGVVWSPSRAPIALIVYYTQ +ASADARAKEDVIASVARIVVQ-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000751B685 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAVATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. AU17325 TaxID=2015348 RepID=A0A228IJ53_9BURK +----FEALAALERDAGGRLGVCAIDTASGRRA-EHRVNERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYAKADLVNYSPVTEKHVDAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGEALPAAQRA +QLVTWMRGNKVGDKRIRAGVPAGWKVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ +ARADAKSKDDVIAGVARIVAKAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000752B56B +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLALGDALPAPQRA +QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPAGGPVALAVYYTQ +ARADARAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI0007567C8D +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA +QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPAGGPVALAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase OXY-1 n=1 Tax=Enterobacterales bacterium 8AC TaxID=2653184 RepID=A0A654BMP5_9GAMM +-qQAQQQLAALEKASGGRLGVVAINTADGTTL-QLNGGQRFPFCSTFKVIAASAILHHSL +NNNGLMQQRIRYQKSDLVAYSPITEKHLDGGMTVAELCAAALQYSDNTAVNLLMKQLGGP +EAITAYARSIGDSTFRLDRWETELNSAIPGDERDTTTPAAMAASLQKLTLGNALPQAQRE +QLVAWMKGNTTGGKRIRAGVPAGAIVADKTGGGDYGTTNDIGIVWRENRAPLAIVVYFTQ +PQQDAKANNEVIAAAARIVNQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075C9757 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASVRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A1R1J976_9BURK +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARPDAKRKDDVIAAATRIAI--- +>[subseq from] Class A beta-lactamase n=1 Tax=Serratia oryzae TaxID=2034155 RepID=A0A1S8CQC7_9GAMM +-qQAQQQLAALEKASGGRLGVVAINTADGTTL-QLNGGQRFPFCSTFKVIAASAILHHSL +NNNGFMQQRIRYQKSDLVAYSPITEKHLDGGMTVAELCAAALQYSDNTAVNLLMKQLGGP +AAITAYARSIGDSTFRLDRWETELNSAIPGDERDTTTPAAMAASLQKLTLGNALPQAQRE +QLVAWMKGNTTGGKRIRAGVPAGAIVADKTGGGDYGTTNDIGIVWRENRAPLAIVVYFTQ +PQQDAKANNEVIAAAARIVSQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0009820474 +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAASLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000982228D +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWGTELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000757E2D7 +----ASSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAVSLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0004D73547 +----FEALAALERDAGGRLGVCAIDTASGRRA-EHRVNERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYAKADLVNYSPVTEKHVDAGMTVAALCEAAIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDLRDTTTPAAMAASMRELMVGETLPAAQRA +QLVTWMRGNKVGDKRIRAGVPAGWKVGDKTGTGDYGTTNDAGVIWPTSGAPIVLVVYYTQ +ARADAKSKDDVIAGVARIVAKAf +>[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. CCM 8695 TaxID=2609281 RepID=UPI001420611B +--DAHASLAALEKAAGGRLGVAALDTGTGRQL-GHRASERFPMCSTFKAIAAAAILAHAS +KVPGLLAQRVRYTRADLVTYSPITEQELDKGMTVAELCEATIQYSDNAAANLLMKLIGGP +AGVTAFARSVGDATFRLDRWETELNTAIPGDPRDTTTPQAMTTLLRRVALDDGLPPAQRD +QLQEWMRGNTTGAARIRAGVPAGWAVADKTGTGAYGSSNDIGIVFPPKGAPVVLALYYTQ +AAPDAKANSEILAAATRIVMEHf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007563B86 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWSPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A119HGA0_9BURK +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRASVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000DACA787 +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPLCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVHYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia TaxID=32008 RepID=UPI000841CDF8 +-----DALAELERSAGGRLGVCAIDIASGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV +DRPALLQKRVRYTKADLVNYSPVSGKHVDDGMTVAALCEATIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGEALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPVALAVYYTQ +ARADARAKDDVIASVARIVVRAf +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia thailandensis TaxID=57975 RepID=A0A659JMJ0_BURTH +--AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAVLARSA +GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALDTAQRA +QLNAWMLGNKTGDARIRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM +RSRNAQARDDVIASAARIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264) TaxID=271848 RepID=UPI00098014B6 +--AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAVLARSA +GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGTAQRA +QLNAWMLGNKTGDARIRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM +RSRNAQARDDVIASAARIAARAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007583351 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWSPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520G0T8_9BURK +--ALSTQLAAIEKASGGRLGVGILDTAAGHSA-GHRQDERFPLCSTFKFLAGAAVLARVD +QRKERLDRRVTFERRDLVTYSPVTEKHVGPGITVAELCDAAITLSDNTAGNLLLASLGGP +QGLTAFMRSIGDTHTRLDRTEPTLNEARAGDPRDTTTPGAMARSMQKILLGDALTPASRA +QLLQWLDANKTGGERIRAGLPADWKVGDKTGSGANGATNDVAILRPPARAPILLAIYLTE +TQASAPARNKTLASVAQAVA--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756D903 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVSEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMVASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000754B8D7 +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA +QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075472C9 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRASVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754E976 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRASVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B82C7 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADATRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000753168B +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWSPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. HMSC10F09 TaxID=1581083 RepID=UPI0008A1EBFE +-----ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDSTAANELMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDVGVMWPPSRAPIVLAVYYTQ +TRADAKAKDDVIATATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE6CC7 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAIMIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075823A2 +-----TSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QYAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B6B85 +----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRASVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. RF2-non_BP3 TaxID=1637844 RepID=A0A102EVG8_9BURK +----ATSFAALERAAGGRLGVCAIDTASGLHA-LHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLQQRVTIAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +EAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPVQRA +RLIAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVATf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075BB1B1 +----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKRVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWEVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000759D102 +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTFTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPGGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARAKDDVIASVARILVQAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A108IZ65_9BURK +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADATRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Serratia sp. Ag1 TaxID=1524467 RepID=A0A087L3C7_9GAMM +-qQAQQQLAALEKASGGRLGVVALNTADGQML-QLNAEQRFPFCSTFKVIAASAILHHSL +SHGGFMQQRIRYQQSDLVTYSPITEQHLDSGMTIAELCAAALQYSDNTAVNLLMKQLGGP +AAITAYARSIGDTTFRLDRWETELNSAIPGDERDTTTPAAMAASLQKLTLGNALPKAQRE +QLVAWMKANTTGDKRIRAGVPAGARVADKTGGGDYGTTNDIGIVWQANRAPLVIVVYFTQ +PQQDAKAKNEVIASAAQIVSQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759C902 +----ATSLAELERAAGGRLGVHAFDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLDWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARVDAKRKDDVIAAATRIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas sp. BR0G17 TaxID=2269368 RepID=UPI0013DF26C6 +--ALADTCTRLEAGSGGRLGVGLLDTAGGRMI-GHRLDERFPMCSTFKALAAGVVLARVD +RKQENLDRRVNYTKSDLVTYSPATEKHVEGGMTIAELCEAAITLSDNTAGNLLLASFGGP +AGLTSFARSLGDETTRLDRIETELNQALPGDPRDTTSPRAMAQTLRALTLGDALSATSRA +QLIAWLKANTTGGTRLRAGVPSGWAVADKTGTGDHGTANDVAVLWPPQRAPLIVTVYLTG +AAVARDQQNKIIADIGAAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia thailandensis TaxID=57975 RepID=A0A2N8R726_BURTH +--AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAVLARSA +GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGTAQRA +QLNAWMLGNKTGDARIRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM +RSRNAQARDDVIASAARIAARAf +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia thailandensis TaxID=57975 RepID=UPI00016A8E6C +--AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAVLARSA +GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGTAQRA +QLNAWMLGNKTGDARIRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM +RSRNAQARDDVIASAARIAARAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756F314 +----ATSLAELERAAGGRLGVHALDIATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756C6EB +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +TRPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAVATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Massilia sp. GV090 TaxID=2135673 RepID=A0A4R2WHV7_9BURK +-----SAFAALEKDLGGRLGISAVNLATGKQV-GHRSGERFPMCSTFKAMVAAAILQRSA +SDPALLKRRISYTKADLVPHAPVTEKHIDQGMTVEELCAAMVQYSDNPAANLLMKVLGGP +EAVTAFARSIGDTDFRLDRWETELNSAIPGDPRDTTTPQAMMRSLQALVMGDALPAPQRQ +QLKDWLVGNTTGAKLIRAGVPAGWTVGDKTGGGAYGARNDIAVIWPPGQAPIVIAVYTAH +EKADAKYREDIIAGATSTA---- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. 2002721687 TaxID=1468409 RepID=A0A0D5L6X1_9BURK +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKMMLSAAVLARSA +DDAALLQRRIPYAKRDLVRYSPITERHVGAGMTVAELCAATLQYSDNTAANLLIDLLGGP +QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLAGDALGAAQRA +QLNAWMLGNKTGDARLRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM +RSQNAPVRDDVIAAAARIAARAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000980EB5C +---AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDSSAANLLMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ +TRADARAKDDVIASVARIVAQTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI0007569088 +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLALGDALPAPQRA +QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWSPAGGPVALAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE99DA +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRAEERFPFCSTFKAILIAAVLAESV +ACPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F4FE2 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +TRPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAVATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFEBD6D +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLSEWLRGNKVGDKRIRAGVPTAWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +ARADAKAKDDVIAAATRIAI--- +>[subseq from] LUT family class A extended-spectrum beta-lactamase n=1 Tax=Chitinimonas sp. BJB300 TaxID=1559339 RepID=A0A2G3K1G1_9BURK +---TKARLQKLESDFGGRLGVFAVDAANGAVL-SYRADERFPFCSTFKVLAASAILNKSG +DVAGLMQQRINYSQSDLVNYSPITEKHVADGMTIAELCAAAIQYSDNTAANLLIKTLGGP +DAITAFARSIGDTKFRLDRWETALNTAIPGDPRDTSTPEAMGRSLQRLVLGDALAREQCE +QLRDWLYGNTTGAARIKASIPADWKIGDKTGTGSYGTANDIAFVWPPQRKPVVIAIYTTQ +DKEDAQARNDVIASAARILVD-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A117XR52_9BURK +-----TSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFAQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QYAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759A5D6 +----ASSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +ARPALFMQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKGKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754C0B3 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARSALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADATRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D6C95 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRT +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWSPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SVU6_9BACT +---LATKLAEIEARLGARLGVAILDTQTGRHW-EHRADERFPLCSTFKVLACGAILARAD +VGQEDLDRRIRFEASDVVTYSPVTQNRVGGEMTLAELCEAAITQSDNTAGNLILESLGGP +HSVTEFARSLGDSVTRLDRWETDLNEAKPGDPRDTTTPKAVLADLQSLILENVLSRQSRE +QLARWMVANKTGDAKLRAGLPDDWRIGDKTGGGDYGTMNDVAVIWPPDREPLIISVYMTE +SEASFDDRNAAVADIGRAV---- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D6BDB +----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGL +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia paludis TaxID=1506587 RepID=UPI0004DB7204 +---AAQLLADLERDAGGRLGVCAIDVASGRQA-AYRADERFPFCSTFKTLLSGAVLAQSV +ERPALLQQRVTYGKADLVNYSPVTEQHVGTGMTVAALCEAALQHSDNSAANLLMKLLGGP +SAVTAYARSIGDDVFRLDRWETELNTALPGDLRDTTTPAAMVASVRALMLGDALPAAQRA +QLVAWMRGNQVGGKRFRAGVPAGWTVADKTGTGDYGTTNDVGVVWSPSRAPAVLVVYYTQ +AGADARPKEDVIASAARIVIQAf +>[subseq from] class A beta-lactamase n=1 Tax=Xenophilus azovorans TaxID=151755 RepID=UPI000A8CD459 +---ARERLAAIESGFDGRLGVFAIDTADGATL-AHRGDERFPLCSTFKLVAAAALLARST +AEPRLMSERVHYTRAELASWSPVAEKHVARGMTYEELCAAAVMYSDNTAANLMLRRLGGP +AALTDYARGLGDAAFRLDRWEPELNTAIPGDPRDTTTPAAMARTVRRLVLDDALPAPQRA +QLEAWLRGNTTGATRIRAGVPSTWAVGDKTGAGDYGTNNDVGVLWPPGRAPIVLAVYTTQ +RQPDAKARNDVIAEAARAVAQ-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756320B +----ASSLAELERAAGGRLGVHALDTATGRRV-LHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAVATRIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=UPI0011F00B60 +-kRLADAIAALETRSGGRLGVAVLDTGTGQRF-GHRADERFPMCSTFKFLLAGAVLKRVD +EGRERLDRRIPVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPTVGDP +AGLTAFLRTLGDQKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRD +QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGTRGTANDVGIVWPEGRAPLLIASYLTE +TADAFKERDAIHAGVARAVAD-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE0756 +----ATSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWSPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia thailandensis TaxID=57975 RepID=Q2T5A3_BURTA +--AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAVLARSA +GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGTAQRA +QLNAWMLGNKTGDARIRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM +RSRNAQARDDVIASAARIAARAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075EB3E0 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPRARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075BED4D +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAVVLAESV +ARPALFTRRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMVASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia complex TaxID=87882 RepID=UPI00075BEAE2 +----ATSFAALERAAGGRLGVCAIDTASGLHA-LHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLQQRVTIAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +EAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPVQRA +RLIAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVATf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000751AFE6 +----ASSLAELERAAGGRLGVHVLDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVTAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075FC8A7 +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPVLLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA +QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007594016 +-----TSLAEFERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A6B9AWB4_PSEST +-eDLTHRFAALEKQLQARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD +AGADSLQTRIRYTADDLVTYSPVTEQHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP +GAIGDFARTLGDRFTRLDRWETELNEARPGDPRDTTTPAAMAANLQRLVLGDSLSAASRD +QLIAWMLASQTGAAKLRAGLPPTWRLGDKTGSGERGTTNEIAVIWPPQRQPVIACVYLTQ +TQASAEERNAALAAIGRALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A1B4LN50_9BURK +----AATFAALERAAGGRLGVYALDTATGRRV-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWETELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QYVQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKGRDDVIAAAARIAVATf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007550135 +-----TSLAELERAEGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QYAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000CF0C82C +-----QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV +ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPCDLRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ +ARADARSKDDVIASVARILVQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000760B681 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADGRFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754A0BC +-----TSLAELERAAGGRLGVHALDTATGWRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDRGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QYAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007551C3E +----ATSLAELERAAGGRLGVHALDTVTGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075415F6 +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA +QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000755708C +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLALGDALPAPQRA +QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPSAGGPVALAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000F5620A2 +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA +QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPAGGPVALAVYYTQ +ARADARAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. MSMB0856 TaxID=1637869 RepID=UPI00075B6F39 +----ATSFAALERAAGGRLGVCAIDTASGLHA-LHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLQQRVTIAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +EAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRVGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVATf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075DAB9C +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYHQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLALGDALPAPQRA +QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWSPAGGPVALAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Serratia oryzae TaxID=2034155 RepID=UPI0012E2BD6C +-qQAQQQLAALEKASGGRLGVVAINTADGTTL-QLNGGQRFPFCSTFKVIAASAILHHSL +NNNGFMQQRIRYQKSDLVAYSPITEKHLDSGMTVAELCAAALQYSDNTAVNLLMKQLGGP +EAITAYARSIGDSTFRLDRWETELNSAIPGDERDTTTPAAMAASLQKLTLGNALPQAQRE +QLVAWMKGNTTGGKRIRAGVPAGAIVADKTGGGDYGTTNDIGIVWRENRAPLAIVVYFTQ +PRQDAKANNEVIAAAARIVNQAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075721B3 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRVDERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKGKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000757D4A6 +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRLEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDVGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075ABDC5 +----ASSLAELERTAGGRLGVHALDTATGRRV-QHCADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000752FA4B +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRLEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A1B4Q267_BURCE +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAMLSAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +SAVTAFARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMLGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKGKDDVIAAATRIAI--- +>[subseq from] UPI00132CDA17 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00132CDA17 +--AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAVLARSA +GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAADLLIALLGGP +QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGTAQRA +QLNAWMLGNKTGDARIRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM +RSRNAQARDDVIASAARIAARAf +>[subseq from] class A beta-lactamase n=1 Tax=Rugamonas rubra TaxID=758825 RepID=UPI000B879395 +--TAEARLAALESGWGGRLGVFAIDTANERSI-GFRAGERFAFCSTFKVMLAAAVLERSK +QVPDLLQQRIKYAKSELVNYSPITEDHVEDGMSVAELCAAGIQYSDNTAANLLIKLLGGT +AAVTAYARAIGDQEFRLDRWETELNTAIPGDPRDTTTPAAMGRSLRRLAVGEALPAPLRA +QLQDWMRGNTTGDARIRAGVPAGWQVGDKTGTGDYASANDIGVVWPPQRAPIVLAVYTAQ +ADKDAKANSEVIAAATRIVLEH- +>[subseq from] Beta-lactamase n=6 Tax=Klebsiella TaxID=570 RepID=Q5PXN8_KLEPN +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAARIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075949B1 +-----TSLAELERAEGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFAQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QYAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Rugamonas rubra TaxID=758825 RepID=A0A1I4SPD7_9GAMM +--TAEARLAALESGWGGRLGVFAIDTANERSI-GFRAGERFAFCSTFKVMLAAAVLERSK +QVPDLLQQRIKYAKSELVNYSPITEDHVEDGMSVAELCAAGIQYSDNTAANLLIKLLGGT +AAVTAYARAIGDQEFRLDRWETELNTAIPGDPRDTTTPAAMGRSLRRLAVGEALPAPLRA +QLQDWMRGNTTGDARIRAGVPAGWQVGDKTGTGDYASANDIGVVWPPQRAPIVLAVYTAQ +ADKDAKANSEVIAAATRIVLEH- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075EA2BD +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRLEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDVGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Nafp2/4-1b TaxID=2116686 RepID=A0A495YSC9_9BURK +----AKSFASLERAAGGRLGVCAIDTASGRRA-LHRADERFPFCSTFKAMLSAAVLAQSV +EHPGLLQQRVTYGQADLVNYSPVSSKHVGTGMTVAELCEAAIQYSDNAAANLAMKLLGGP +AAVTAYARTIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ +TRADAKAKDDVIAAAARIAVATf +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium viridifuturi TaxID=1654716 RepID=UPI00067EDDC8 +-qRLQEEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKAMLSAAVLHRVD +RGESSLDQRMQVEAKDILAYAPVAKQHVGSGMTLAELCEAAVTLSDNTAANLLLREIGGP +AGLTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKNLQRVMLGDVLQAASRQ +KLVDWMVANKTGDTRLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMEKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A118HZB6_9BURK +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QYAQWLLGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARPDAKRKDDVIAAATRIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Agrobacterium sp. a22-2 TaxID=2283840 RepID=UPI00144582A9 +---MAATLQEIERRIAARLGVAILDMETGRQW-SHRGDERFPMCSTFKAIASAAVLARVD +AGQEDLERRIKISADDIIAHAPAAEKRIGGFMTMGELCAAAVTLSDNTAANLILKSLGGP +EGFTRFLRSIGDKTTRLDRWEPELNEAKPGDPRDTTTPAAMAKTLQTLVTGDALTPQSRQ +QLSAWMIANTTGAGKLRAGLPRDWVVGDKTGSGRLGTANDIAVLWPPERKPIFVAVYITE +TKATMDDRNAAMAEIARTMV--- +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=A0A1Q1MQ04_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYSPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A4P9DY74_PSEST +-eDLTHRFAALEKQLQARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD +AGADSLQTRIRYSADDLVTYSPVTEQHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP +GAIGDFARTLGDRFTRLDRWETELNEARPGDPRDTTTPAAMAANLQRLVLGDSLSAASRD +QLIAWMLASQTGAAKLRAGLPPTWRLGDKTGSGERGTTNEIAVIWPPQRQPVIACVYLTQ +TQASAEERNAALAAIGRALAE-- +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=A8DS72_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYSPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia latens TaxID=488446 RepID=A0A1B4P284_9BURK +----ATSFAALERAAGGRLGVCAIDTASGRRA-LHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVMYGQADLVNYSPVSGKHVGTGMTVAQLCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDAFRLDRWETELNTALPGDVRDTTTPAAMAASLRALVLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPPGSQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ +AQPEAKAQEDVIAAAARIAVATf +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. DFCI-1 TaxID=1230476 RepID=U1I9A1_9BRAD +-qRLQEEFARIELATSGRLGVAALDMETGLRA-NRRGDERFPMCSTFKAMLSAAVLHRVD +RGESSLDQRMQVEAKDILAYAPVAKQHVGSGMTLAELCEAAITLSDNTAANLLLREIGGP +AGLTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKNLQRVVLGDVLQAASRQ +KLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMDKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A345IT65_9BURK +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA +QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPAGGPVALAVYYTQ +ARADARAKDDVIAAATRIAV--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9126 TaxID=2184570 RepID=A0A3N8BD33_9BURK +---AATSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPSCSTFKAMLIAAVLAQSV +TRPALLAQRVTYRQADLVRYSPVTEKHVGAGMTVGELCEATAQYSDNSAANLLMKLLGGP +AAVTAFARAIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA +QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVTLAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas palustris TaxID=1076 RepID=UPI000D1A767A +--ALADTCARLEAGSSGRLGVGVLDTASGRMI-GHRLDERFPMCSTFKALAAGLVLARVD +RRQDNLDRRVNYTKSDLVTYSPATEKHVEGGMTIAELCEAAVTLSDNTAGNLLLASFGGP +AGLTAFARSLGDETTRLDRIETELNEALPGDPRDTTSPRAMAQTLRALTLADALSATSRA +QLIAWLKANTTGGTRLRAGVPSGWVVADKTGTGDHGTANDVAVLWPPQRAPLIVTVYLTG +AAVARDQQNKIIADVGAAVAD-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D005AB9 +-----ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDSTAANELMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ +TRADAKAKDDVIATATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F1C23 +----ASSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMTASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWSPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007526A06 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGVALPAPQRA +QFAQWLLGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. SRS-46 TaxID=2094191 RepID=A0A4R4CHE4_9BURK +-----TSLEALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLTQSV +ARPALLAQRLMVRQADMVGYSPVTEKHVGTEMTVGELCEATAQYSDNAAANLLMKLLGGP +SAVTAFMRTIGDDTFRLDRWETDLNTALPGDPRDTTTPAAMAASLRVLALGDALPAPQRA +QFTAWLRGNKTGDRRIRAGVPAGWQVGEKTGTGDYGTTNDIGVLWPPARGPIALAVYYTQ +ASPDAKAKDGVIAAAARIVIA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000757EE52 +----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGL +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKGKDDVIAAATRIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Massilia TaxID=2609279 RepID=UPI000D3197BC +-----SAFAALEKDLGGRLGISAVNLATGKQV-GHRSGERFPMCSTFKAMVAAAILQRSA +SDPALLKRRISYTKADLVPHAPVTERHIDQGMTVEELCAAMVQYSDNPAANLLMKVLGGP +EAVTAFARSIGDTDFRLDRWETELNSAIPGDPRDTTTPHAMMRSLQALVVGDALPAPQRQ +QLKDWLVGNTTGAKLIRAGVPAGWTVGDKTGGGAYGARNDIAVIWPPGQAPIVIAVYTAH +EQADAKYREDIIAGATSTA---- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=A0A118Q2C0_BURPY +-----TSFDALERAAGGRLGVCAIDTATGRRV-QYRADERFPFCSTFKAMLIAAVLAQSV +TRPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLALGGALPAPQRA +QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPAGGPVALAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=A0A107APN2_9BURK +-----TSFDALEHAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA +QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobium sp. LTSP885 TaxID=1619232 RepID=A0A0D7NQZ6_9BRAD +-qRLQQEFARIELATSGRLGVAALDTETGLRA-SLRGDERFPMCSTFKALATAAVLHRVD +RGESSLDQRVQIQAKDILAYAPITKEHVGSDMTLSELCEAAITQSDNTAANLLLRELGGP +AGLTNFFRTIGDNVSRLDRWEVALNEGVSGDPRDTTSPAAMLKNLQRVVLGDVLQATSRQ +KLADWMVANKTGDARLRAGVPRDWRVGDKTGTGDRGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPAAKCDEVIANVARAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Afipia sp. 1NLS2 TaxID=666684 RepID=D6VB26_9BRAD +-qDLKSKISRIESRVKGRLGVAVLDTGSDRRF-GYRKDERFPMCSTFKLMAAAAILKRVE +QGQETLERRVHFSQSDLVTYSPATEKHLESGMTVAELCEAAITLSDNTAGNLMLGMLGGP +PGVTAFARALGDPLTRLDRTELALNEAVPGDPRDTTTPAAMAEDLRKLMFGGALAKASSE +QLKAWLLANKTGDARLRARLPAGWRVGDKTGSGERGSTNDVGILWPPDAAPLIAAVYLTQ +TAASMNERNEALAAVGEAVAAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759011D +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAVLIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPVPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADATRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. DCY119 TaxID=2108445 RepID=A0A3A3I1R5_9RHIZ +--DAAAQLRALEKKYGGRLGVAILDTASGTRI-EHRADERFALCSTFKVLASAAVLARVD +KGEEKLDRRITYEKKDLVTYSPVTEKHVGKKMALAELCEAAITLSDNTAGNLLLASFGGP +AGLTAYARTLGDEVTRLDRIETALNEAKTGDPRDTTTPAAMLADLQKLVLGDGLSPASRD +QLKTWLLANKTGDKRLRAYLPKDWKVGDKTGTGDNGSANDVGILWPPKHGPIIVSSYFTE +SSASTDEKNIVHAEVGRIAA--- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A1S7BHJ3_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D4L6Q1_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +EGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. BDU8 TaxID=1385592 RepID=A0A1B4FTV3_9BURK +---AERQLGELESSFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAILARSA +GDATLLRRRIPYAKRDLVSYSPITEKHVGEGMTVAELCAAMLQYSDNTAANLLIALLGGP +QAVTAYARSIGDTTFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGAAQRA +QLDTWMLGNTTGGARIRAGVPADWRVADKTGTGDYGTGNDIGVAYPPNRAPIVIVIYTTM +RDKNAQARDDVLASAARIAARTf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000757778F +----ATSLAELERAAGGRLGVHALDTVTGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADATRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobiaceae TaxID=41294 RepID=A0A336JT72_9BRAD +-eQFAAKLADLEAGSGGRLGVGVLDTANGRMT-GHRLDERFPMCSTFKALAAGLVLARVD +RGQESLDRRVRYAASDLVTYSPATEKHVEDGMTIAELCEAAITLSDNTAGNLLLASFGGP +VGLTAFARSLGDETTRLDRIETELNEALPGDPRDTTSPRAMAQDLRALTLGDALSATSRA +QLIAWLKANTTGGTRLRAGVPAGWAVGDKTGTGDHATANDVAVLWPPQRPPLIVTVYLTG +ATVARDQQNKIIAAVGAEVVRAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=H6V561_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007544704 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPVPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADATRKDDVIAAATRIAI--- +>[subseq from] class A extended-spectrum beta-lactamase CTX-M-140 n=1 Tax=Proteus mirabilis TaxID=584 RepID=UPI0007A58C76 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075B825B +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA +QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWSPAGGPVALAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F7EA1 +----ATSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDRRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVTAAATRIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000988A2CF +-eDLTHRFAALEKQLEARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD +AGADSLQTRIRYSADDLVTYSPVTEQHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP +GAIGDFARTLGDRFTRLDRWETELNEARPGDPRDTTTPAAMAANLQRLVLGDSLSAASRD +QLIAWMLASQTGAAKLRAGLPPTWRLGDKTGSGERGTTNEIAVIWPPQRQPVIACVYLTQ +TQASAEERNAALAAIGRALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Chania multitudinisentens RB-25 TaxID=1441930 RepID=W0LJ18_9GAMM +---AQQQLAALEKASGGRLGVVVIDTAGGETL-QLNGEQRFPFCSTFKMMVAGAILHHSV +SNPGFMQQPVRYSKSDLVAHSPVTEKHLNRGMSVAELCAATIQYSDNAAANLLMKQLGGP +AAITAFARSIGDTAFRLDRWETELNSAIPGDERDTTTPAAMASSLQKLALGNALPEAQRE +QLVIWMKGNTTGDQRIRAGVPAGAIVADKTGGGSYGTTNDIGIVWQEKRAPLVIAIYFTQ +PQQDAKANNEVIASATRIASQAf +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI0006B990F5 +-eDLTHRFAALEKQLQARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD +AGADSLQTRIRYSADDLVTYSPVTEQHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP +GAIGDFARTLGDRFTRLDRWETELNEARPGDPRDTTTPAAMAANLQRLVLGDSLSAASRD +QLIAWMLASQTGAAKLRAGLPPTWRLGDKTGSGERGTTNEIAVIWPPQRQPVIACVYLTQ +TRASAEERNAALAAIGRALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. MH-G8 TaxID=1854588 RepID=A0A263DPN4_9PSEU +----TDRLAELERRFDARLGVYALDTGSGREV-AHRADERFAMCSTFKALAAAAVLDATP +--PEHLDQRVHYAQADLVDYSPVTEQHVADGMTIRELCDAAVRFSDNTAGNLLLADLGGP +GGITALARSLGDDVTRLDRIEPELNTAIPGDERDTTSPRAMAGCLDALVLGDRLGPDDRA +LLTGWLVGNTTGDARIRAGVPDGWRVGDKTGTGSYGTTNDVGVVWPPDRAPIVLVLLSSR +TTEDADNEDALLAEATRVVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=H6V562_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARSIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI0008418112 +--DAQRALRELEASFDGRIGVAALDTATNAKI-AYRADERFAFCSTFKMMLSAAVLARSA +AEPDLLPRRIVYAKRDLVEYSPITGKHAGAGMTTAELCAAALQYSDNTAANLLISLLGGP +QAVTAYARSIGDAEFRLDRRETELNTAIPGDLRDTTTPSAMAASLRRLLLGDALGQAQRE +QLNAWMLGNTTGNERIRAGVPPAWRVADKTGTGDYGTANDIGVLYPPGRAPIVLAIYTTG +RAQQARARNDVIASAARIVARAf +>[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=A0A2T2Y7V0_9ENTR +--AVQQKLAALEKSSGGRLGVALIDTEDNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFAREIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium mercantei TaxID=1904807 RepID=UPI000B5ADCA9 +-qRLQQEFARIELATTGRLGVAALDMETGLRA-SRRGDERFPMCSTFKAMLSAAVLHRVD +RGESSLDQRMQVEAKDILAYAPVAKQHVGSGMTLAELCEAAVTLSDNTAANLLLREIGGP +AGLTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKNLQRVMLGDVLQAASRQ +RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDVGVFWPPGRKPIVVTVYLTG +ASAPMDKCNEVIANVARAVS--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000841C062 +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNYSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGNYGTTNDAGVVWLPSRAPIVLTVYYTQ +ARADAKAKENVIAAAARIAVATf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1S7BHI2_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARSIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008420CD1 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFWLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKGKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. HMP271 TaxID=1487922 RepID=A0A099RVB7_9PSED +-eDLTHRFAALEKQLQARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD +AGADSLQTRIRYTTDDLVTYSPVTEQHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP +GAIGDFARTLGDRFTRLDRWETELNEARPGDPRDTTTPAAMAANLQRLVLGDSLSAASRD +QLIAWMLASQTGAAKLRAGLPPTWRLGDKTGSGERGTTNEIAVIWPPQRQPVIACVYLTQ +TQASAEDRNAALAAIGRALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. TSV86 TaxID=1385594 RepID=A0A103ED48_9BURK +--DAQRSLRELEASFDGRIGVAALDTATNAKI-AHRADERFAFCSTFKMMLSAAVLARSA +AEPDLLPRRIAYAKRDLVEYSPITGKHVGAGMTAAELCAAALQYSDNTAANLLISLLGGP +QAVTAYARSIGDAVFRLDRWETELNTAIPGDLRDTTTPSAMAASLHRLLLGDALGQVQRE +QLNGWMLDNTTGNERIRAGVPTAWRVADKTGTGDYGTANDIGVLYPPGRAPIVLAIYTTG +RVQQARARNDVIASAARIVARAf +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium mercantei TaxID=1904807 RepID=UPI0009786C1C +-qRLQQEFARIELATTGRLGVAALDMETGLRA-SRRGDERFPMCSTFKAMLSAAVLHRVD +RGESSLDQRMQVEAKDILAYAPVAKQHVGSGMTLAELCEAAVTLSDNTAANLLLREIGGP +AGLTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKNLQRVMLGDVLQAASRQ +RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDVGVFWPPGRKPIVVTVYLTG +ASAPMDKCNEVIANVARAVS--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075F7D2B +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA +QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWSPAGGPVALAVYYTQ +ARADARAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Variovorax TaxID=663243 RepID=A0A109BSD1_9BURK +--DLARQFAEIEKKTGGRLGVHVLDTATARRA-GHRQDERFAMCSTFKFLAAALVLARVD +QGKERLERRITYARDELVTYSPVTEKHAGTDMSMAQLCEAAVTLSDNTAANLMLASVGGP +AGLTAFMRSLGDPHTRLDRIEPGLNEARAGDPRDTTTPAAMVDSMQKILLGDALSPGSRA +LLLQWLDDNKTGGERIRAGLPADWKVGDKTGTGENGAANDIAILRPPGRPPVLLSVYLTE +TKASMADRNAAHAAVAAAVV--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075C799B +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKTMLGAAVLARSV +EHPGLLQQRVTYAQADLVNYSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTSYARSIGDDTFRLDRWETALNTALPGDPRDTTTPAAMAASIRALTLGDALPAPQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ +ARADAKAKENVIAAAARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D009FAF +-----ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV +AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA +QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVMWPPSRAPIVLAVYYTQ +TRADAKAKDDVIATATRIAI--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075C6EC0 +----ASSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMMVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKGKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=W0T351_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Caballeronia choica TaxID=326476 RepID=A0A158KK39_9BURK +---SASRLKALEDASNGRLGVAAFNTADGAQL-SYRADERFPFCSTFKLLLTSAILARSA +HDDGLLARRITYAQGDLVNYSPVSEKHVADGMTVAELCAAALQYSDNSAANLLIRLLGGP +SAVTAFARSIGDHEFRLDRMETELNTAIPGDLRDTTTPAAMARDLQRLALGDALGTAQRD +QLQTWMRGNTTGDARVRAGVPRDWQVADKTGTGDYGTSNDIAVLWPPAKPPIVVVIYFTQ +REPDAKARNDVIASAAKIIAGRf +>[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium zhangyense TaxID=1776730 RepID=UPI0013EC91E8 +--DAAAQLRALEKKYGGRLGVAILDTANGTRI-EHRADERFALCSTFKVLASAAVLARVD +KGEEKLDRRITYEKKDLVTYSPETEKHAGKKMTLAELCEAAITLSDNTAGNLLLASFGGP +AGLTAYARTLGDEVTRLDRIETALNEAKTGDPRDTTSPAAMLADLQKLVLGDALSPASRD +QLKTWLLANKTGDKRLRAHLPKDWKVGDKTGTGDNGSANDVGILWPPKRGPIIVSSYFAE +SSASTDEKNTVHAEVGRIAA--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007564A1D +----ATSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +SRPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDRRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVTAAATRIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. R5(2019) TaxID=2697566 RepID=UPI001411F7E2 +------RCAALEKQLNGRLGVFALDTGNDTQL-GYRATERFAVCSTFKMMLAAAVLKFSE +RKPGVLQQRLRYSKSELVSYSPVTERYIDEGMTVAELCAAAVQYSDNTAANLLIKLLGGP +SAVTEFARSIGDQAFRLDRWETELNTAIPGDPRDTSTPAAMGRSLQRLVLGNALEPAQAA +QLQAWLRGNTTGDERIRAGVPSGWQVGDKTGTGDYASASDIGVVWPPQRAPIVVAIYTTQ +PEKDAKPRNDIIAEAARVVAD-- +>[subseq from] Beta-lactamase n=10 Tax=Bacteria TaxID=2 RepID=Q9L5C6_KLEPN +--AVQQKLAALEKSSGGRLGVALIDTKDNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFAREIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodopseudomonas palustris TaxID=1076 RepID=A0A2R4GPD3_RHOPL +--ALADRCARLEAGSGGRLGVGVLDTAGGSMI-GHRLDERFPMCSTFKALAAGLVLARVD +RKQESLDRRVSYAKSDLVTYSPATEKHVEGGMTIAELCEAAITLSDNTAGNLLLASFGGP +AGLTAFARSLGDDTTRLDRIETELSQALPGDPRDTTSPRAMAQTLRALTLGDALSATSRA +QLIAWLKANTTGGTRLRAGVPSGWVVADKTGTGDNGTANDVAVFWPPQRAPLLVTVYLTG +ATVARDQQNKIIADVGVAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A560BJX7_AZOBR +-kRLADAIAALEKRSGGRLGVAVLDTGTGQRF-GHRADERFPMCSTFKFLLAGAVLKRVD +EGSERLDRRIPVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFLRTLGDQKTRLDRNEPSLNSAIPGDPRDTTTPAAMAQSMERLMLGDALTAASRD +QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE +TPDSFKERDATHAGVARAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. MSHR3999 TaxID=1542965 RepID=A0A0D0FMP9_9BURK +----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAVVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSISDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Andreprevotia chitinilytica TaxID=396808 RepID=UPI000556022C +--SMQARFAKLEADLNGRLGVFAVNTANGAQL-QYRADERFAFCSTFKMMLASAILARSA +QVDGLLQQRIPYAQGDLVSYSPITEKHVGEGMAVADLCAAAVQYSDNTAANLLIKLLGGP +AAVTAFARSIGDRVFRLDRWETALNTAIPGDPRDTTTPKAMGLSLQRLALGDALTPPLAT +QLQDWLRGNTTGAARIRAGVPADWQVGDKTGTGDYGSANDIGVVWPPQGAPIVIAIYTTL +REKDGKARNDVIAAAARVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. IDO3 TaxID=1705310 RepID=A0A2A4CHA6_9BURK +----TTTFAALERAAGGRLGVCAIDTASGRRA-QHRADARFPFCSTFKTMLSAAVLAQSV +ERPGLLQQRVMIGQGDLVNYSPVSSKHVGTGMTVAALCEAAIQYSDNSAANLLMKMIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLTLGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVMWPPSGAPVVLVVYYTQ +ARADAKAKDDVIAAAARIAVATf +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000536CB97 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTFKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0006222E5C +----AATFAALERAAGGRLGVCAIDTASGWRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVTWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ +ARADAKAKENVIAAAARIAVATf +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. PBL-H6 TaxID=434009 RepID=UPI0013A58E12 +--ALARQFAEIEKKTGGRLGVHVLDTANGRRA-GHRQDERFAMCSTFKFVAAALVLARVD +RGQERLDRRVAYSRNDLVTYSPVTEKHAGTDMTMAQLCEAAVTLSDNTAGNLMLASFGGP +AGLTAFMRSLGDAHTRLDRIETALNEARAGDPRDTTTPAAMVGSMQKILLGDALSPASRT +QLLQWLDGNKTGGERIGAGLPADWKVGDKTGTGENGAANDIAILRPPGRAPILLSVYLTE +TKASMADRNAAHAAVAAAVV--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007574EB7 +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKRVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMVASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWSPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] UPI00065004F1 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00065004F1 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas yeongjuensis TaxID=377616 RepID=UPI001390BD6C +------QLEALEHRYGGRLGVSILDTGSGKRI-GHRADERFPMCSTFKFLAAAQVLTRVD +RGEEKLERRIVFAKKDLVAYSPMTEKHAGAPMTLAELCHAAITLSDNTAGNLLLDSFGGP +AGLTAFARTLGDTVTRLDRRETELNEAIPGDPRDTTTPAAMLDDMRRLLLGDALSPASRK +QLADWLLANTTGAARLRAGLPGDWRVGDKTGTGANGASNDIAIVWPPDRAPLLVTAYYAE +SSIPQETRNAVLVEVGRIAA--- +>[subseq from] Beta-lactamase Toho-1 n=3 Tax=Escherichia coli TaxID=562 RepID=UPI0001B04C54 +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAENRNDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A385FUV0_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYSPIAEKHVNGTMTLAELSAAVLQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia latens TaxID=488446 RepID=UPI000757CD4C +----ATSFAALERAAGGRLGVCAIDTASGRRA-LHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVMYGQADLVNYSPVSGKHVGTGMTVAQLCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDAFRLDRWETELNTALPGDVRDTTTPAAMAASLRALVLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPPGSQVADKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ +AQPEAKAQEDVIAAAARIAVATf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000756828D +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVTWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ +ARADAKAKENVIAAAARIAVATf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0004F59A9C +----ATSFAALERAAGGRLGVCAIDTASGRRA-LHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVMYGQADLVNYSPVSGKHVGTGMTVAQLCEAAIQYSDNSAANLAMKLIGGP +AAVTAFARSIGDDAFRLDRWETELNTALPGDVRDTTTPAAMAASLRALVLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPPGSQVADKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ +AQPEAKAQEDVIAAAARIAVATf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=A0A3N8RBQ2_9BURK +-----QMLADLERSAGGRLGVCAIDIATGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVTYTQADLVNYSPVSGKHVDDGMTVAALCEATIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGEALPAAQRA +QLVAWMRGNKVGDKRIRAGVPAGWTVADKTGTGDYGTTNDAGVVWSPSRAPIALVVYYTQ +ASADARAKEDVVASVARIVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium tropici TaxID=398 RepID=A0A2T0NYI7_RHITR +-qRLQEEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKAMLSAAVLHRVD +RGESSLDQRMQVEAKDILAYAPVAKQHVGSAMTLAELCEAAVTLSDNTAANLLLREIGGP +AGLTSFFRTIGDNVSRLDRWEVELNEAMPGDPRDTTSPVAMLKDLQRVMLGDVLQAASRQ +RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMEKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=F1CLN0_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRE +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5P8NAV4_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDKTFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000F57C891 +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA +QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ +ARADALAKDDVIAAATRIAI--- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=UPI000BA179AB +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075E75C5 +----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEVTAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRASVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKGKDDVIAAATRIAVA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Capsulimonas corticalis TaxID=2219043 RepID=A0A402CT55_9BACT +--SAQAQFASLEKSLNGRLGVYALNTADGSQM-SYRADERFPLCSTFKIMLASAILHRSA +RTPELLGRRIRYTAQDLVTYSPITEKHVGDGMTIAELCAAALQYSDNTAANQLMKILGGP +AAVTAFSRLIGDRVFHLDRWETELNTAIPGDLRDTSTPRAMGRSLKRLALGDALPPHQRR +QLQEWMRGNTTGKKRIAAGVPANWLVGDKTGTGDYGSANDVAILWPPRHAPILLAIYTTQ +HEKNAKAREDVIASAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp9017 TaxID=2184565 RepID=A0A3P0NIN3_9BURK +----ATSFAALEHAAGGRLGVCAIDTASGRRA-QHRAGERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVMVGQGDLVNYSPMSSKHVGTGMTVAALCEAAIQYSDNSAANLLMKMIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDQRDTTTPAAMAASLRVLALGDALPAAQRA +QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVMWPPSGAPVVLVVYYTQ +TRADAKAKDAVIAAAARIAVATf +>[subseq from] Beta-lactamase n=5 Tax=Klebsiella TaxID=570 RepID=Q206M3_KLEPN +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKLLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000975B6F3 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTFKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIIYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=UPI0002D93B0D +-----TSFDALERAAGGRLGVCAIDTATGRRV-QYRADERFPFCSTFKAMLIAAVLAQSV +TRPALLVQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLALGGALPAPQRA +QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPAGGPVALAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3G4RJI0_KLEPN +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp9125 TaxID=2184569 RepID=A0A3N8BY78_9BURK +---AATSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +TRPALLAQRVTYRQADLVRYSPVTEKHVGAGMTVGELCEATAQYSDNSAANLLMTLLGGP +AAVTAFARAIGDDTFRLDRWETELNTALPGDARDTTTPAAMAASLRVLALGDALPAPQRA +QFAAWLRGNKTGDKRIRAGAPAGWQVGDKTGTGDYGTTNDVGVLWPPAREPVTLAVYYTQ +ARADAQAKDDVIAAATRIAL--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007582E69 +----ASSLAELERAAVGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKLVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2U8T2W7_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAEHRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=4 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A1W1H4E2_ECOLX +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAIIWPENHAPLVLVTYFTQ +PEQKAESRRDVLAAAAKIVTHSf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1Q1MQ23_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A346D4G3_KLEPN +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAEHRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q5MAG1_KLEPN +-nAVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=7 Tax=Enterobacterales TaxID=91347 RepID=Q4LB53_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. AU29985 TaxID=2153378 RepID=A0A2R7YEI3_9BURK +----ATSFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSI +AQPALLQQRVAYGKADLVSYSPVTEQHVGAGMTVAELCAATIQYSDNTAANVLMKLIGGP +QAVTAYARSIGDATFRLDSWETELNT-LPGDPRDTTTPAAMAASLRALMLGDALPSAQRA +QFVEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVAWPPSGAPIVLAVYYTQ +ARADARAKDDVIAAATRIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754CE3B +----ASSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMMVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALVLGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWSPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAVA-- +>[subseq from] Beta-lactamase n=2 Tax=pseudomallei group TaxID=111527 RepID=A0A291CER7_BURTH +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKMMLSAAVLARSA +DDAALLQRRIPYAKRDLVRYSPITERHVGAGMTVAELCAATLQYSDNTAANLLIDLLGGT +QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLAGDALGAAQRA +QLNAWMLGNKTGDARLRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM +RSQNAPVRDDVIAAAARIAARAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI0007581400 +-----TSFDALECAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA +QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2S1PK93_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0007058CA7 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTFKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGGYGTANDIGVAYPPNRAPIVFIIYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=32 Tax=root TaxID=1 RepID=Q840M4_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0S1Z1Z4_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=D2KL97_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAENRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas citronellolis TaxID=53408 RepID=A0A1A9KHQ2_9PSED +--STLERLQQLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACVLARVD +RGEEQLARRIVYGQADLVEYSPVSERHVGQPMSVAELCEAAITLSDNGAANLLLASLGGP +TGLTDWLRSTGDDVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDVLQPASRD +QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG +SPASAEKREAVLAEVGRLA---- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1S6KJQ0_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3G2I6P7_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=51 Tax=Gammaproteobacteria TaxID=1236 RepID=Q9L5C7_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] UPI001019E979 UniRef100 entry n=2 Tax=unknown TaxID=N/A RepID=UPI001019E979 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia pseudomallei TaxID=28450 RepID=A3NJ57_BURP6 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTFKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIIYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A345IT62_9BURK +----AAALADLERNAGGRLGVCAIDTASGRSV-EHRPNERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYSKADLVNYSPVTERHVDTGMTVAAMCEAAIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDLRDTTTPAAMAASTRVLTLGDALPAAQRA +QLVTWLRGNKVGDKRIRAGMPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ +AQADARSKDDVIASAARIV---- +>[subseq from] LUT family class A beta-lactamase n=1 Tax=Pseudomonas luteola TaxID=47886 RepID=A0A5P2SA86_PSELU +--SFQDRLAKLEQQLNGRLGVCAIDTANGAQL-GYRANERFAMNSTFKVMLASAFLARSQ +DEPGLLEERLTYTRADLVTYSPVTEKHVATGMTVAELCAAGIQYSDNTAANVLMKKLGGP +EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTSTPQAMAMSLQRLALGDMLAADKQH +QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRRAPVVLALYSAL +ESQQAEARNDVLADAARIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. VT-16-41 TaxID=1953765 RepID=A0A1V2VB31_9BURK +--SIVQKLAQLEADIGGRLGVSLVDTVHGRQW-GYRADERFPMCSTFKFLAAAAVLRRVD +EGRERLARRIVYRQQDLVPYSPTTGKHTGGALSMAQLCEAAITLSDNTAANLMLASMGGP +AGLTGFVRTLGDELTRLDRNEPTLNEAIPGDPRDTTTPAAMTADLRQVVLGNALAPASRE +QITQWLLANQTGDKRVRAGLPAGWKVGDKTGTGDRGTANDVGVVWTPQGAPLLFAVYLTE +NTAEAARRDAVHAEVGRLIAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Salmonella derby TaxID=28144 RepID=B6E9R8_SALDE +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVAWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase (Fragment) n=118 Tax=Bacteria TaxID=2 RepID=A2TCA1_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A104JDJ7_9BURK +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAETV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDESFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVLTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLAVYYTQ +ARADAKRKDDVIAAATRFAI--- +>[subseq from] Beta-lactamase n=17 Tax=Gammaproteobacteria TaxID=1236 RepID=C8CP57_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=R4I5F6_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRHDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A142IX48_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAKSRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=2 Tax=Azospirillum brasilense TaxID=192 RepID=G8AUN0_AZOBR +-kRLADAIASLEKRSGGRLGVAVLDTGTGQRF-GHRADERFPMCSTFKFLLAGAVLKRVD +EGRERLDRRIPVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFLRTLGDQKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRE +QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE +TPDAFKERDAIHAGVARAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. HH01 TaxID=1198452 RepID=L9PCN3_9BURK +-----ALLAKLEAESGGRLGVAALNTADGRRL-LHRADERFPFCSTFKMMLSAAVLAREP +---ALLKKRVAYRKSDLVTYSPITEKHVGKGMTVAALCEATIQYSDNAAANLLMKQIGGP +AAVTAFARSIGDTEFRLDRIETELNTALPGDPRDTTTPDAMAESLNKLLLGDALGAAQRK +QLKDWMLGNTTGDTRIRAGVPAGSVVADKTGTGDYGTTNDIGVIWQPGKAPIVLVVYLTQ +PGKDDKARSEILAEASKIVVEAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas sp. BR0C11 TaxID=2269370 RepID=UPI0013E073C0 +--ALADTCARLEAGSGGRLGVGVLDTAGVRTI-GHRLDERFPMCSTFKALAAGVVLARVD +RKQESLGRRVNYTKSDLVTYSPATEKHVEGGMTIAELCEAAITLSDNTAGNLLLASFGGP +AGLTAFARSLGDETTRLDRIETELNQALPGDPRDTTSPRAMAQTLRALTLGDALSATSRA +QLIAWLKANTTGGTRLRAGVPSGWAVADKTGTGDNGTANDVAVLWPPQHAPLIVTVCLTG +AAVARDQQNKIIADVGAAVAD-- +>[subseq from] UPI0012F477AB UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0012F477AB +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGAGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075CDA67 +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAVSLRVLALGDALPAPQRA +QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ +ARADALAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase Toho-1 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0006526492 +--SVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAERRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=Q2L9X2_ECOLX +--AMQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q939K2_KLEPN +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAK-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia latens TaxID=488446 RepID=UPI001248D7FD +----AASFAALERAAGGRLGVCAIDTASGRRA-LHRADERFPFCSTFKAMLSAAVLAQSV +ERPGLLQQRVTYGQADLVDYSPVSARHVGTGMTVAQLCEAAIQYSDNSAANLAMKLIGGP +PAVTAYARSIGDDAFRLDRWETELNTALPGDVRDTTTPAAMAASLRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ +ARPDAKAKDDVIAAAARIAVATf +>[subseq from] Beta-lactamase LUT-5 n=1 Tax=Pseudomonas luteola TaxID=47886 RepID=C0LP01_PSELU +--SFQDRLAKLEQKLNGRLGVCAIDTADGAQL-GYRANERFAMNSTFKVMLASAFLAQSQ +DEPGLLEERLTYTRADLVTYSPVTEKHVATGMTVAELCAAGIQYSDNTAANVLMKKLGGP +EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTSTPQAMAMSLQRLALGDMLAADKQH +QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRRAPVVLALYSAL +ENQQAEARNDVLADAARIVAE-- +>[subseq from] LUT family class A beta-lactamase n=1 Tax=Pseudomonas luteola TaxID=47886 RepID=UPI000F7B0D93 +--SFQDRLAKLEQQLNGRLGVCAIDTANGAQL-GYRANERFAMNSTFKVMLASAFLARSQ +DEPGLLEERLTYTRADLVTYSPVTEKHVATGMTVAELCAAGIQYSDNTAANVLMKKLGGP +EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTSTPQAMAMSLQRLALGDMLAADKQH +QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRRAPVVLALYSAL +ENPQAEARNDVLADAARIVAE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075CC45B +-----TSLAELELAEGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QYAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=I0DEV3_ECOLX +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAIIWPENHAPLVLVTYFTQ +PEQKAESRRDVLAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A560D427_AZOBR +-kRLADAIAALETRSGGRLGVAVLDTGTGQRF-GHRADERFPMCSTFKFLLAGAILKRVD +EGRERLERRIPVTKADLVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPTAMVHSMERLMLGDALTPASRE +QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGARGTANDVGIVWPEGRAPLLIASYLTE +TADGFKERDAIHADVARAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Shigella sp. SH284 TaxID=1074436 RepID=G3EPW3_9ENTR +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKRSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. AU15512 TaxID=2015345 RepID=A0A228GHS1_9BURK +-----QMLAELERSAGGRLGVCAIDIATGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV +DRPALLQQRVMYTQADLVNYSPVSGKHVDDGMTVAALCEATIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGEALPAAQRA +QLVAWMRGNKVGDKRIRAGVPARWTVGDKTGTGDYGTTNDAGVVWSPAGASVALAVYYTQ +ARADARAKDDVIASVARIVVRAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264) TaxID=271848 RepID=UPI00098014DD +--AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAVLARSA +GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTT----------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=3 Tax=Pseudomonas TaxID=286 RepID=N2IP96_9PSED +--SFQDRLAKLEQQLNGRLGVCAIDTANGAQL-GYRANERFAMNSTFKVMLASAFLARSQ +DEPGLLEERLTYTRADLVTYSPVTEKHVSTGMTVAELCAAGIQYSDNTAANVLMKKLGGP +EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTSTPQAMAMSLQRLALGDMLAADKQH +QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRRAPVVLALYSAL +ENQQAEARNDVLADAARIVAE-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0005368FF4 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +SEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDERIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9002 TaxID=2184558 RepID=UPI000F5F882E +---AATSFDALERAAGGRLGVCAIDTATGRRV-LHRADERFPFCSTFKAMLIAAVLAQSV +TRPALLAQRVTYRQADLVRYSPVTEKHVGAGMTVGELCEATAQYSDNSAANLLMKLLGGP +AAVTAFARAIGDDTFRLDRWETELNTALPGDARDTTTPAAMAASLRVLALGDALPAPQRA +QFAAWLRGNKTGDKRIRAGAPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVTLAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. JL972 TaxID=2652396 RepID=UPI0012D981AC +-eDLTHRFAALEKQLQARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD +AGADSLQTRIRYSADDLVTYSPVTEQHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP +GAIGDFARTLGDRFTRLDRWETELNEARPGDPRDTTTPAAMAANLQRLVLGDSLSAASRG +QLIAWMLASQTGAAKLRAGLPPTWRLGDKTGSGERGTTNEIAVIWPPQRQPVIACVYLTQ +TQASAEERNAALAAIGRALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. CG23_2 TaxID=1706231 RepID=A0A0S4P1X0_9BURK +-----PRLAALEKAAGGRLGVAALDTGNGRQV-GHRADQRFPMCSTFKAIAAAAILAHGK +NVPGLLAQRIRYTKADLVTYSPITEQELDKGMTVAELCEATIQYSDNAAANLLMKLIGGP +AGVTAFARSVGDTTFRLDRWETELNTAIPGDPRDTTTPQAMATLLRRVALDDGLAPAQRD +QLQEWMRGNTTGAARISAGVPAGWAVADKTGTGAYGSSNDIGIVFPPKGAPVVLALYYTQ +AAPDAKANSEILAAATRIVMEDf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. Tr-862 TaxID=2608331 RepID=UPI0014198451 +----ATSFAALEHAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EQPGLLQQRVTYGPSDLVNYSPVSGKHVGTGMTVAELCEATIQYSDNSAANLAMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ +ARADAKPKDDVIAAAARIAVA-- +>[subseq from] UPI00132CDA14 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00132CDA14 +--AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFYSTFKTMLSAAVLARSA +GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGTAQRA +QLNAWMLGNKTGDARIRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM +RSRNAQARDDVIASAARIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Collimonas sp. OK242 TaxID=1798195 RepID=A0A1H3B4T4_9BURK +---VARQLREIEARSGGRLGVAVLDTHNGQAH-AYRGDERFPMCSTFKLLAAGLTLKRVD +RGQEQLTRRIRYDAADLVAYSPATEKHTGAGMSVAQLCEAAITLSDNTAANLLLHSLGGP +AHLTAYVRSLGDQVTRLDRIEPELNQASPGDPRDTTSPNAMLSTMRQLVLGTALSADARQ +QLTNWLLANTTGDQRLRAYLPAGWRVADKTGSGVHGTTNDIGILFPPDRAPLVVTAYLTG +TKASAATRDAALAEVGRLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=R4I5F7_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLRGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Salmonella derby TaxID=28144 RepID=B6E9R7_SALDE +--AVQQKLAALEKSSGGRLGVALIDTADNTHV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] BETA-LACTAMASE TOHO-1 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00001D8713 +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAERRRDILAAAAKIVTHGf +>[subseq from] beta-lactamase CTX-M-27 n=2 Tax=Escherichia coli TaxID=562 RepID=UPI0000508B91 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKHADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B8BB2FE +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRWEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000753EB08 +-----TSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFAQRVTYRQADLLEWSPVTEKNVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALAFGDALPAPQRA +QYAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=K7WEV5_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGSYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=I3VNW0_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAD-- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A4D8RNY7_AZOBR +-kRLADAIAALEKRSGGRLGVAVLDTGTGQSF-GHRADERFPMCSTFKFLLAGAVLKQVD +EGRERLDRRIRVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTSASRD +QLIAWMVANRTGDKRLRAGLPKGWRIGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE +TPDTFKERDATHAGVARAVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. CI-1B TaxID=2511166 RepID=A0A508T6I6_9BRAD +-qRLQQAFSRIEQGTGGRLGVAALDSETGLRA-GLRGDERFPMCSTFKALASAAVLRRVD +RGESSLDQRVRFEAKDILANSPVTKEHVASGMTLAEICEAAITRSDNTAGNMILHEIGGP +EGLTSFFRAIGDNVSRLDRWELALNEAVPGDPRDTTSPTAMLKNLQRVLLGDALSATSRK +TLTDWMVANKTGDARLRAGVPADWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ATAPADKCNEAIASVARAVA--- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759A0AE +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAAILLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Afipia felis TaxID=1035 RepID=A0A380WBR3_AFIFE +-eNLKDRISRIEAKVEGRLGVAVLDTGSGRSF-GYRENERFPMCSTFKLMAAAAILKRVE +QKQETLEWRVHFTKSDLVTYSPVTEKHIESGMTVAELCEAAITLSDNTAGNLMLAMLGGP +SGVTAFARALGDPLTRLDRTEPTLNEAVPGDVRDTTTPAAMAENLQKLIFGHALAKASSA +QLQAWLLANKTGDARLRARLPSGWRVGDKTGSGERGSTNDIGILWPPDSAPIIVAAYLTE +TAAPADKRNAALAEVGDAAA--- +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=F1DG66_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRE +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=Q934I0_BURPE +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTFKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075D220B +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETEVNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ +ARADAKPKDEVIAAAARIAVAAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2U8T0X7_KLEPN +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=E9LZM3_ECOLX +--AVRQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=B0FTT8_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFSQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] inhibitor-resistant class A extended-spectrum beta-lactamase CTX-M-219 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000CA39C7A +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVIYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SBP4_9BACT +--AVQQKLAALEKSSGGRLGVALIDIADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Massilia sp. GV097 TaxID=2135674 RepID=A0A4R3UTE4_9BURK +-----SAFAALEKDLGGRLGISAVNLATGKQV-GHRSGERFPMCSTFKAMVAAAILQRSA +SDPALLKRRISYTKADLVPHAPVTEKHIDRGMTAEELCAAMVQYSDNPAANLLMKVLGGP +EAVTAFARSIGDTDFRLDRWETELNSAIPGDPRDTTTPQAMMRSLQGLVVGDALPAPQRQ +QLKDWLVGNTTGAKLIRAGVPAGWTVGDKTGGGAYGARNDIAVIWPPGQAPIVIAVYTAH +EQADAKYREDIIAGATSTA---- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. UFLA03-84 TaxID=418599 RepID=A0A2A2VEY6_9BRAD +-qRLQEEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKAMLSAAVLHRVD +HGESSLDQRMQVEAKDILAYAPVAKQHVGSGMTLAELCEAAVTLSDNTAANLLLREIGGP +AGLTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVTMLKNLQRVMLGDALQAASRQ +KLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMEKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=R9S6T8_KLEPN +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRE +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobium sp. LTSPM299 TaxID=1619233 RepID=A0A0D7QH22_9BRAD +-qRLQQEFARIELATSGRLGVAALDTETGLRA-SLRGDERFPMCSTFKALATAAVLHRVD +RGESSLDQRVQIQAKDILTYAPITREHVGSDMTLSELCEAAITQSDNTAANLLLRELGGP +AGLTSFFRTIGDNVSRLDRWEVALNEGVSGDPRDTTSPAAMLKNLQRVVLGDVLQATSRQ +KLTDWMVATKTGDARLRAGAPRDWRVGDKTGTGDRGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPAAKCDEVIANVARAVAN-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00092A2AD8 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAEHRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=46 Tax=Bacteria TaxID=2 RepID=A3RJI2_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A386JTM5_ECOLX +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRIEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Duganella sp. HH101 TaxID=1781066 RepID=A0A1E7WQM9_9BURK +-----ALLAKLEAESGGRLGVAALNTADGRRL-LHRADERFPFCSTFKMMLSAAVLAREP +---ALLKKRVAYRKTDLVTYSPITEKHVGQGMTVAALCEATIQYSDNAAANLLMKQIGGP +AAVTAFARSIGDTEFRLDRIETELNTALPGDPRDTTTPEAMAESLQKLLLGDALGAAQRK +QLKDWMLGNTTGDTRIRAGVPAGSLVADKTGTGDYGTTNDIGVIWQPNKAPIVLVVYLTQ +PGKDDKARSEILAEASKIVVEAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000759A40E +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDETFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ +ARADAKAKENVIAAAARIAVATf +>[subseq from] Beta-lactamase n=1 Tax=Cupriavidus basilensis OR16 TaxID=1127483 RepID=H1S0N1_9BURK +haAAQDRLAALESAAGGRLGVAALNTASGAQL-SHRANERFALCSTFKVLAVSAILRRSA +TEGGMLQRRIAYTKAELVAYSPITEKHAGAGLTVAELCAAALQYSDNTAANLLMQLLGGP +AAVTAFARAIGDDTFRLDRWETELNTAIPGDPRDTSTPAAMAASLQRLTLGDALGGAERE +RLVAWMRGNTTGATRIRAGVPADWLVADKTGSGDYGTANDIGVAWPPGKPPIVLAIYFTQ +PGKDAVYRNDVLASAARIAAE-- +>[subseq from] Beta-lactamase LUT-4 n=1 Tax=Pseudomonas luteola TaxID=47886 RepID=C0LP00_PSELU +--SFQDRLAKLEQKLNGRLGVCAIDTANGAQL-GYRANERFAMNSTFKVMLASAFLARSQ +DEPGLLEERLTYTRADLVTYSPVTEKHVSTGMTVAELCAAGIQYSDNTAANVLMKKLGGP +EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTSTPQAMAMSLQRLALGDMLAADKQH +QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRRAPVVLALYSAL +ESQQAEARNDVLADAARIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=E2IZP4_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075CCDD4 +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETGLNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA +QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWSPAGGPVALAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=5 Tax=Enterobacterales TaxID=91347 RepID=D0EW47_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075E9A0D +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVTWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ +ARADAKAKENVIAAAARIAVAAf +>[subseq from] Beta-lactamase n=2 Tax=Pseudomonadales TaxID=72274 RepID=Q4F896_ACIBA +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGGYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAERRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sp. SH165 TaxID=1074431 RepID=G3EPV8_9ENTR +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEEHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A1S7BHI4_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFPMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase Toho-1 n=3 Tax=Enterobacteriaceae TaxID=543 RepID=BLT1_ECOLX +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAERRRDILAAAAKIVTHGf +>[subseq from] UPI000FE1826D UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI000FE1826D +--ALADMCARLEAGSGGRLGVGVLDTASGRMI-GHRLDDRFPMCSTFKVLAAGLVLARVD +RKQENLDRRVSYAKSDLVTYSPATEKHVEDGMTIAELCEAAITLSDNTAANLLLASFGGP +AGLTAFARSLGDETTRLDRIETELNEALAGDPRDTTSPRAMAQDLRALTLGDALSPASRA +QLITWLKANTTGGTRLRAGVPPGWTVGDKTGTGGRGTANDIAVLWPLQRAPLIVTVYLTG +ATVVRDQQNKIIADVGAAVA--- +>[subseq from] UPI001161557A UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI001161557A +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGNKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. BH-1 TaxID=2058884 RepID=A0A2N6J8G9_9BURK +--SVVQKLARLEADIGGRLGVSLVDTVHGRQW-GYRADERFPMCSTFKFLAAAAVLRRVD +EGRERLARRIVYRKQDLVPYSPTTGKHTGGALSMAQLCEAAITLSDNTAANLMLTSMGGP +AGLTGFVRTLGDDLTRLDRNEPTLNEAIPGDPRDTTTPAAMTDDLRQVVLGNALAPASRE +QITQWLLANQTGDKRVRAGLPAGWKVGDKTGTGDRGTANDVGVVWTPQGAPLLFAVYLTE +NTAEAARRDAVHAEVGRLIAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Rugamonas sp. FT103W TaxID=2660640 RepID=UPI00128D1FF4 +-----ALLAKLEAESGGRLGVAALNTADGRRL-LHRADERFPFCSTFKMMLSAAVLAREP +---ALLKKRVVYRKTDLVTYSPITEKHVGKGMTVAALCEATIQYSDNAAANLLMKQIGGP +AAVTAFARSIGDTEFRLDRIETELNTALPGDPRDTTTPEAMAESLQKLLLGDALGAAQRK +QLKDWMLGNTTGDTRIRAGVPAGSLVADKTGTGDYGTTNDIGVIWQPNKAPIVLVVYLTQ +PGKDDKARSEILAEASKIVVEAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia TaxID=32008 RepID=UPI000757C214 +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVTWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ +ARADAKAKENVIAAAARIAVATf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5A4UAP9_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRHDVLASAARIIAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Cupriavidus basilensis TaxID=68895 RepID=A0A643FN87_9BURK +--AAQDRLAALESAARGRLGIAALNTANGARL-SHRANERFALCSTFKVIAASAVLQRSA +TQAGLLQRRIAYKKDELVAYSPITEKHVGDGLTVAELCAAALQYSDNTAANLLMKLLGGP +AAVTAFARAIGDDQFRLDRWETELNTALPGDPRDTSTPAAMAASLQRLTLGDALGGAERE +QLVAWMRGNTTGATRIRAGVPADWQAAEKTGSGDYGTANDIGVAWPPGKPPIVLAIYFTQ +PGKDAAYRNDVLASAARIAAE-- +>[subseq from] Beta-lactamase LUT-2 n=1 Tax=Pseudomonas luteola TaxID=47886 RepID=C0LNZ8_PSELU +--SFQDRLAKLEQQLNGRLGVCAIDTANGAQL-GYRANERFAMNSTFKVMLASAFLARSQ +DEPGLLEERLTYTRADLVTYSPVTEKHVSTGMTVAELCAAGIQYSDNTAANVLMKKLGGP +EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTSTPQAMAMSLQRLALGDMLAADKQH +QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRRTPVVLALYSAL +ENQQAEARNDVLADAARIVAE-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000978064C +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +SEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Providencia rettgeri TaxID=587 RepID=G9JVK3_PRORE +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGGYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000536A31E +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +SEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A3FFV8_ECOLX +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAENRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A132DV04_BURVI +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ +ARADAKAKENVIAAAARIAVATf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Providencia stuartii TaxID=588 RepID=C5MRF6_PROST +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase CTX-M-2 n=76 Tax=Bacteria TaxID=2 RepID=BLC2_SALTM +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A244B8Y3_ECOLX +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase CTX-M-97 n=1 Tax=Escherichia coli TaxID=562 RepID=BLC97_ECOLX +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A1A5D1T5_9PSED +--STLERLQQLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACVLARVD +RGEEQLARRIVYGQADLVEYSPVSERHVGQPMSVAELCEAAITLSDNGAANLLLTSLGGP +TGLTDWLRSTGDDVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDVLQPASRD +QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG +SPAPAEKRDALLAEVGRLA---- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI000F8066D5 +-----TSFDALERAAGGRLGVCAIDTATGRRV-QYRADERFPFCSTFKAMLIAAVLAQSV +TRPALLVQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGGALPAPQRA +QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPAGGPVALAVYYTQ +ARADAQAKDDVIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica subsp. enterica serovar Agona TaxID=58095 RepID=B6E9S0_SALET +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPFAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A132DK91_BURVI +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVAWMRGNTVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ +ARADAKAKENVIAAAARIAVATf +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A3X3S6E6_SALER +--SVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=Q8VN24_9ENTR +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAIIWPENQTPLVLVTYFTQ +PEQKAESRRDVLAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2R4G6X4_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=I3VNW6_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTH +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Jeongeupia sp. USM3 TaxID=1906741 RepID=A0A1D9BCU2_9NEIS +--AASAQFSALEKKYRGRLGVCLLDTASGVQT-GYRADERFAFCSTFKVMLAGAILERST +RVAGLLQQRISYKQSEVVSYSPVSGKHVADGMTVSGLCAAAVQYSDNTAANLLIKLLGGP +AAVTAFARSIGDREFRLDRWETALNSAIPGDPRDTTTPAAMARSLQTLALGDALPLPQRT +QLQDWLRGNTTGDKRIRAGVPAGWRVGDKTGSGDYGTTNDIAVLWPPGRAPVVLAVYFTQ +PDAKAKWQDEVIAAATRIAVS-- +>[subseq from] Beta-lactamase n=1 Tax=Duganella sp. HH105 TaxID=1781067 RepID=A0A1E7VAM9_9BURK +-------LAKLEAESGGRLGVAALNTADGRRL-LHRADERFPFCSTFKMMLSAAVLAREP +---ALLKKRVAYRKTDLVTYSPITEKHVGQGMTVAALCEATIQYSDNAAANLLMKQIGGP +AAVTAFARSIGDTEFRLDRIETELNTALPGDPRDTTTPEAMAESLQKLLLGDALGAAQRK +QLKDWMLGNTTGDTRIRAGVPAGSLVADKTGTGDYGTTNDIGVIWQPNKAPIVLVVYLTQ +PGKDDKARSEILAEASKIVVEAf +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. SK17 TaxID=2057741 RepID=A0A2K8YN58_9BRAD +-qRLQQELARIELATTGRLGVAAFDMETGLRA-NHRGDERFPMCSTFKAMLSAAVLHRVD +RGESSLDQRVQIEAKDILAYAPVTKQHVGTSMTVSELCVAVGTLSDNTAANLLLREIGGP +AGLTAFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKNLQRVAFGDVLQPASRQ +RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIIVTVYLTG +ASAPMDKCNEVIANVARAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Caballeronia TaxID=2646786 RepID=UPI0013EC416B +--TAEDQLKQLESSAGGRLGVAALNTADGKQV-NYRADERFPLCSTFKLVLVSAVLKQSE +LQKGLLERRIHYTQSELLSWAPITKKQIATGMTVAELCAAALQYSDNTAANLLIKLVGGP +ETVTAFARSIGDTQFHLDRWEPELNTAIPGDPRDTSTPAAMAQSLQRVTLGDALGASQRS +QLQTWLLGNTTGADKIAAALPAHWMVGDKTGSGDYGTTNDIGVIWPPGKPPIVLAIYLTQ +REQGAKARDDVVASAARIVVGAf +>[subseq from] Beta-lactamase n=1 Tax=Cupriavidus sp. SK-3 TaxID=1470558 RepID=A0A069I8A9_9BURK +--AAQDRLAALESAAGGRLGVAALNTASGARI-SHRASERFALCSTFKVLAASAILQRSA +AESGLLQRRIAYTKDELVAYSPVTGKHTGDGMTVSELCAAALQYSDNTAANLLMKILGGP +AAVTAFARSIGDDAFRLDRWETELNTAIPGDPRDTSTPAAMSRSLQRLALGDALGAAERG +RLVAWMRGNTTGATRIRAGVPADWQVADKTGSGDYGAANDIAVAWPPGKPPVVMAIYFTQ +GDKDAAYRNDVLATAARIVAE-- +>[subseq from] Beta-lactamase Toho-1 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00004EAC5B +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSCDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAERRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Shigella sp. SH257 TaxID=1074435 RepID=G3EPW2_9ENTR +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) TaxID=258594 RepID=Q6NCV7_RHOPA +--ALADMCARLEAGSGGRLGVGVLDTASGRMI-GHRLDDRFPMCSTFKVLAAGLVLARVD +RKQENLDRRVSYAKSDLVTYSPATEKHVEDGMTIAELCEAAITLSDNTAANLLLASFGGP +AGLTAFARSLGDETTRLDRIETELNEALAGDPRDTTSPRAMAQDLRALTLGDALSPASRA +QLITWLKANTTGGTRLRAGVPPGWTVGDKTGTGGRGTANDIAVLWPLQRAPLIVTVYLTG +ATVVRDQQNKIIADVGAAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Cupriavidus basilensis TaxID=68895 RepID=UPI000307A36E +haAAQDRLAALESAAGGRLGVAALNTASGAQL-SHRANERFALCSTFKVLAVSAILRRSA +TEGGMLQRRIAYTKAELVAYSPITEKHAGAGLTVAELCAAALQYSDNTAANLLMQLLGGP +AAVTAFARAIGDDTFRLDRWETELNTAIPGDPRDTSTPAAMAASLQRLTLGDALGGAERE +RLVAWMRGNTTGATRIRAGVPADWLVADKTGSGDYGTANDIGVAWPPGKPPIVLAIYFTQ +PGKDAVYRNDVLASAARIAAE-- +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=J7KCB4_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1E1G7Y0_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGGGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Kluyvera sp. N03-0461 TaxID=280338 RepID=Q6IUM8_9ENTR +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +RQQNAESRRDVLASAARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=UPI000486BDD9 +-qRLQQEFARIELATSGRLGVAVLDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRVD +RGESSLDQRVQIEAKDILAYAPVTKGRVGSAMTLSELCAAAIKLSDNTAANLLLREIGGP +AGFTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKDLQRVLLGDVLSAASRQ +KLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMEKCNEVIANVARAVAN-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia sp. MSMB1589WGS TaxID=1636425 RepID=UPI0007B93839 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKMMLSAAVLARSA +DDAALLQRRIPYAKRDLVRYSPITERHVGASMTVAELCAATLQYSDNTAANLLIDLLGGT +QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLAGDALGAAQRA +QLNAWMLGNKTGDARLRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM +RSQNAPVRDDVIAAAARIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. AP07 TaxID=1144304 RepID=J2ZR77_9CAUL +----SRSIIALEARSGGRLGVAALDTQTGATF-AHRADERFAMCSTFKALVAGLVLARVD +QGKERLDRRIAYGKDVLVTHSPVTERHVGDSMTVGALCEATVTVSDNAAANLLLDTFGGP +SAVTAFVRALGDKVTRLDRREPELNVVRPGEQHDTTSPRAMLGSLRALTLGAALSPASRQ +QMVDWLLANQTGDKRLRAGLPAGWKVGDKTGSWGDGTTNDIAVIWPPGRAPILIAAYLTQ +AKVDSAARDAVIAEVARIVA--- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=Q7X209_ECOLX +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDESFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A1G5NI34_BURVI +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETALNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ +ARADAKAKENVIAAAARIAVATf +>[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas sp. B29 TaxID=95607 RepID=UPI000348E3EA +--ELADPCARLESGSGGRLGVCMLDTATGVVR-GHRLDDRFPLCSTFKVLAAGLVLSRVD +QHQEQLDRRVNYQKQDLVTYSPATEKHVADGMTMAELCAAAITLSDNTAGNLLLASFGGP +PALTAFARGLGDDVTRLDRNETELNEALPGDPRDTTTPRAMAATMRKLVLGDVLSPASRE +QLVAWLKANTTGGTRLRAGVPRGWVVGDKTGTGERGTANDAAVLWPPQRPPVIVAVYLTG +ATVAREQQNATIAAAGAAVVATy +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A560CLJ2_AZOBR +-kRLADAIAALERRSGGRLGVAVLDTGTGQRF-GHRADERFPMCSTFKFLLAGAVLKRVD +EGRERLDRTIPVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLDDALTPASRD +QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLIASYLTE +TADAFKERDAIHAGVARAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=Q936V5_PROMI +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDFLAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0H3YEU2_ECOLX +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGEYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=A0A023PYF0_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVIAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1Z3GWX4_KLEPN +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVYYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium pachyrhizi TaxID=280333 RepID=UPI0012FAEFCB +-qRLQQEFARIELATSGRLGVAVLDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRVD +RGESSLDQRVQIEAKDILAYAPVTKGRVGSAMTLSELCAAAIKLSDNTAANLLLREIGGP +AGFTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKDLQRVLLGDVLSAASRQ +KLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMEKCNEVIANVARAVAN-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0005317EB8 +--AAERQLRELESTFDGRLGFVALDTATGARV-AYRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q937J1_ECOLX +----QQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Kluyvera sp. N03-0462 TaxID=280336 RepID=Q6IUN6_9ENTR +--AVQQKLATLEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIRPTDLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Kluyvera TaxID=2619995 RepID=Q5PU98_9ENTR +--AVQQKLATLEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIRPTDLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium TaxID=374 RepID=UPI000465B64E +-qRLQQELARIELATTGRLGVAAFDMETGLRA-NHRGDERFPMCSTFKAMLSAAVLHRVD +RGESSLDQRVQIEAKDILAYAPVTKQHVGTSMTVSELCVAVGTLSDNTAANLLLREIGGP +AGLTAFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKNLQRVAFGDMLQPASRQ +RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIIVTVYLTG +ASAPMDKCNEVIANVARAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=A0A4U6S4A9_BRAEL +-qRLQQEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRVD +RGESSLDQRMQIEAKDILAYAPVTKAHVGSAMTLSELCAAAVTLSDNTAANLLLREIGGP +AGFTSFFRTIGDNVSRLDRWEVELNEAMPGDQRDTTSPVAMLKDLQRVLLGDVLSAASRQ +KLVDWMVANKTGDARLRAGVPRDWRVADKTGTGERGTYNDIGAFWPPGRKPIVVTVYLTG +ASAPMEKCNEVIANVARAIAN-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00092DDC43 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPQAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas stutzeri TS44 TaxID=477228 RepID=I4JJC6_PSEST +-eDLTQRFAELEKQLDARLGVAIIDSQSGRQW-LQRADERFPLCSTFKLLAGAAVLLRVD +VGADSLQTRIRYGADDLVTYSPVTERHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP +GAIGDFARTLGDHHTRLDRWETELNEARPGDPRDTTTPAAMAANLQRLVLGDSLSAPSRD +QLIAWMLASQTGAAKLRAGLPQDWRIGDKTGSGERGTTNEVAVIWPPQRKPVIACVYLTQ +TQASADARNAALAAIGRALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A077JMT3_KLEPN +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAKLSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759515E +----ATSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDRRIRVGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARADAKRKDDVTAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000EA7F0FC +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCGTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYSPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000EA7F100 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCGTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYSPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=A0A0D1MKS1_BRAEL +-qRLQQELARIELATTGRLGVAAFDMETGLRA-NHRGDERFPMCSTFKAMLSAAVLHRVD +RGESSLDQRVQIEAKDILAYAPVTKQHVGTSMTVSELCVAVGTLSDNTAANLLLREIGGP +AGLTAFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKNLQRVAFGDMLQPASRQ +RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIIVTVYLTG +ASAPMDKCNEVIANVARAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A4D8PNY7_AZOBR +-kRLTDAIAALEKRSGGRLGVAVLDTGTGQSF-GHRADERFPMCSTFKFLLAGAVLKRVD +EGRERLDRPIPVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPTAMVHSMERLMLGDALTPASRD +QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE +TPDTFKERDAIHAGVARAVAD-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000A1A157B +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. K1S02-6 TaxID=2320866 RepID=A0A418XI78_9PSED +----HLQLQQLERAFNGRLGLFALNTGHGAQL-GYRATERFPVCSTFKVLLAAAILQRST +QTPGLMQQRIQYIKRDLVSYSPISEKHLETGMTVAELCAAAVQYSDNTASNLLMKLLGGP +AGVTAYARSIGDAEFRLDRWETDLNTAIPGDPRDTSTPEAMGRSVQRLALGDALQAPQRE +QLQTWLRGNTTGATRIRAGVPSAWQVGDKTGTGDYGTTNDIAVLWPPQRAPVVVAVYVTQ +QAQDAKARNDVVASAARIVV--- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000F09695E +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia complex TaxID=87882 RepID=UPI000754C3B0 +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKTMLGAAVLARSV +EHPGLLQQRVTYAQADLVSSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETALNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ +ARADAKAKENVIAAAARIAVAAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=I3VNV9_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTGIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=2 Tax=Microvirga subterranea TaxID=186651 RepID=A0A370HUN4_9RHIZ +--DPKARLADLERRHGGRLGVAILDTQTGRRI-EHRAGERFAMCSTFKAVAAALVLARVD +RGEERLDRHMTFTKADLVRWSPVTEKHVGTGMTMAQICEAAITSSDNTAGNLMLESFGGP +AALTAYARTLGDSMTRLDRIETALNEATPGDPRDTTTPAAMLGTMEKLLLGEALSGPSRE +QLTAWLVANKTGDRRIRAALPRDWRVGDKTGTGDNGAANDIAILWPPGRGSILIAAYYAE +AKATDEQRNAVLADVGRVAA--- +>[subseq from] class A extended-spectrum beta-lactamase CTX-M-235 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001413AE1F +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLINYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=D1MAH3_ECOLX +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRT +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. JKS000303 TaxID=1938747 RepID=A0A2A9LTL7_9BURK +-----TSFAALERAAGGRLGVCAIDAASGRRA-QYRADERFPFCSTFKTMLSAAVLAQSV +ERPGLLQQRVTYGQGDLVNYSPVSSKHVGTGMTVAALCEAAIQYSDNSAANLLMKMIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASVHVLTLGDALPGVQRA +QLVAWLRGNKVGDKRIRAGVPTGWQVADKTGTGDYGTTNDAGVMWPPSGAPIVLVVYYTQ +TRADAKAKDDVIAAAARIAVATf +>[subseq from] Beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=A0A2Z4TXQ8_SERMA +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A124PVX4_BURVI +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWEIEVNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ +ARADAKAKDEVIAAAARIAVAAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0007535DF2 +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWEIEVNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ +ARADAKAKDEVIAAAARIAVAAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B8BB34A +--AVQQKLAALEKSSGGRLGVAAIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sullae TaxID=50338 RepID=UPI000B351DFD +-dDIERRLAELEKRTGGRLGVSVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD +KGEENLERRVIYHESKLVSYSPETEKHVGGEMSVAELCKAAITLSDNTAGNLLLESFGGP +EALTKWLRSIGDRSTRLDRWETALNEGKKDDPRDTTTPDAMLDTLGNVALGSVLSEPSRN +TLIGWMMANTTGGARLRAGLPGSWKVGDKTGTGNXG------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=L8B2Q9_PROMI +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium tropiciagri TaxID=312253 RepID=UPI00067B29C3 +-qRLQQEFARIELATSGRLGVAALDMETGLRA-SQRGDERFPMCSTFKAMLSAAVLHRVD +RGESSLDQRMQVEAKDILAYAPVAKQHVGSGMTLAELCGAAITLSDNTAANLLLREIGGP +AGLTSFFRTIGDNISRLDRWEVELNEAVPGDPRDTTSPVAMLKNLQRVVLGDILQANSRQ +KLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMEKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=A0A3W6LF28_SALER +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNATGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=4 Tax=Burkholderia pseudomallei TaxID=28450 RepID=H9CTS4_BURPE +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. NAS96.2 TaxID=1680160 RepID=A0A1Q5QVQ9_9BRAD +-qRLQQEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKAMLSAAVLHRVD +RGESSLDQRMQIEAKDILAYAPVAKQHVGSAMTVAELCEAAITLSDNTAANLLLREIGGP +AGMTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTGPVAMLKNLQRVVLGDVLQANSRQ +RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPTEKCNEVIANVARAVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A5B0KZZ9_AZOBR +-kRLADAIAALEKRSGGRLGVAVLDTGTGQSF-GHRADERFPMCSTFKFLLAGAVLKRVD +EGRERLDRTIPVTKADMVPYAPFAETRLGGPPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRE +RLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE +TADTFKERDATHAGVARAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Afipia felis TaxID=1035 RepID=A0A090MSH8_AFIFE +-qDLKSKISRIESRVKGRLGVAVLDTGSDRRF-GYRKDERFPMCSTFKLMAAAAILKRVE +QGQETLERRVHFSQSDLVTYSPATEKHLESGMTVAELCEAAITLSDNTAGNLMLGMLGGP +PGVTAFARALGDPLTRLDRTELALNEAVPGDPRGTTTPAAMAEDLRKLMFGGALAKASSE +QLKAWLLANKTGDARLRARLPAGWRVGDKTGSGERGSTNDVGILWPPDAAPLIAAVYLTQ +TAASMNERNEALAAVGEAVAAAf +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. R5 TaxID=1855320 RepID=A0A1G6R4M3_9BRAD +-qRLQQEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRVD +RGESSLDQRVQIEAKDILAYAPVTKAHVGSAMTLSELCAAAITLSDNTAANLLLREIGGP +AGFTSFFRTIGDNVSRLDRWEVELNEAVPGDQRDTTSPVAMLKDLQRVVLGDVLQTVSRQ +KLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMEKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=Q8VKT5_9ENTR +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIQAGLPKSWVVGDKTGSGDYGTTNDIAIIWPENHAPLVLVTYFTQ +PDQKAESRRDVLAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0001505B76 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=B0BF90_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVTAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNDTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=A0A2V4G2K8_SERMA +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRPEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=B3LE90_9ENTR +-nSVQQQLKALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIQAGLPKSWVVGDKTGSGDYGTTNDIAIIWPENHAPLVLVTYFTQ +PEQKAESRRDVLAAAAKIVTRGf +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000F2520FC +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYSPIAEKHVNGTMSLAELSAAAVQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. TSH58 TaxID=664962 RepID=A0A2S1XDI8_9PROT +-kRLADAIAALETRSGGRLGVAVLDTGTGQRF-GHRADERFPMCSTFKFLLAGAILKQVD +EGRERLDRRIRVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMGRLMLGDALTPASRE +QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLIASYLTE +TADSFKDRDATHAGVARAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=B3LE88_9ENTR +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWGVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDVLAAAAKIVTHGf +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=UPI0013E0E4D9 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTTFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Massilia violaceinigra TaxID=2045208 RepID=A0A2D2DED5_9BURK +---TQARLAALEKAAGGRLGVAAVDTGNGRQM-GHRASERFPMCSTFKAIASAAILAHAR +NVPGLLEQRIRYTKADLVTYSPITEQELDKGMTVAELCEATIQYSDNAAANLLMKLIGGP +AGVTAFARSVGDTTFRLDRWETELNSAIPGDPRDTTTPEAMATLLRRVALDDGLPPAQRD +LLQAWMRGNTTGAARIRAGVPAGWAVADKTGTGAYGSSNDIGIVFPPKGAPVVLALYYTQ +AAPDAKANSDILAAATRIVMEE- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas citronellolis TaxID=53408 RepID=UPI000E2E674D +--STLERLKQLERDSGGRLGVAVLDTGNGRRF-GLREDERFPLCSTFKLLLAACVLARVD +RGEEQLARRIVYGQADLVEYSPVSERHIGQPMSVADLCEAAITLSDNGAANLLLASLGGP +AGLTDWLRSTGDDVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDVLQAASRD +QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG +SPAPAEKRDAVLAEVGRLA---- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderiaceae bacterium 16 TaxID=1619952 RepID=A0A0F0FEC0_9BURK +--AAQDRLAALESAAGGRLGVAALNTANGARI-SHRASERFPLCSTFKVLAASAILQRSA +AESGLLQRRIAYTKDELVAYSPVTGKHAGEGMTVSDLCAAALQYSDNTAANLLMHILGGP +AAVTAFARSIGDDAFRLDRWETELNTAIPGDPRDTSTPASMSRSLRRLALGDALGAAERG +RLVAWMRGNTTGATRIRAGVPADWQVADKTGSGDYGAANDVAVAWPPGKPPVVMAIYFTQ +GDKDAAYRNDVLATAARIVAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Microvirgula aerodenitrificans TaxID=57480 RepID=A0A2U3TGW8_9NEIS +---LTTRVAAIEQSLDARLGVAVIDTGTGREW-AYRGNERFPMMSTFKPLLCSLLLSQVD +QGREMLDRRIEIRPDDLLEHAPVAGKHVGKAMSLGELCEAAITQSDNTAANLVLERVGGP +ARVTAFLRSLGDSKTRLDRNEPTLNEARPGDERDTTMPVAMAGSLKQLVLGQTLSPASRR +QLTDWLVANRTGDAKIRAGLPAGWRVGDKTGSGANGSMNDVAVIWPAGRKPVVLAIFITG +TGASVAARNAAMADITRALVD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q2XT31_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFPMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia oklahomensis TaxID=342113 RepID=A0A381IF48_9BURK +--AAERQLSELESSFGGRLGFVALDTATGARI-AHRAAERFPFCSTFKTMLSAAILARSA +GDATLLQRRIPYAKRDLVSYSPVTEKHVGDGMTVAELCAAALQYSDNTAANLLIALLGGP +QAVTAYARSIGDTTFRLDRRETELNTAIPGDERDTTTPAAMAASLRRLLVGDALGAAQRA +QLDTWMLGNTTGAARIRAGVPADWRVADKTGTGDFGTGNDIGVAYPPSRAPIVIVIYTTM +RDKNAQARNDVLASAARIAARTf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ86_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SGPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ21_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTDGw +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Salmonella infantis TaxID=595 RepID=A0A5X6CG23_SALIN +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFSRAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2H4FY00_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDRTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Microvirgula sp. AG722 TaxID=2183901 RepID=A0A329BCF5_9NEIS +---LTTRVAAIEQSLNARLGVAVIDTGTGREW-AYRGNERFPMMSTFKPLLCSLLLSQVD +QGREMLDRRIEIRPDDLLEHAPVAGKHVGKAMSLGELCEAAITQSDNTAANLVLERVGGP +ARVTAFLRSLGDSKTRLDRNEPTLNEARPGDERDTTMPVAMAGSLKQLVLGQTLSPASRR +QLTDWLVANRTGDAKIRAGLPAGWRVGDKTGSGANGSMNDVAVIWPAGRKPVVLAIFITG +TGASVAARNAAMADITRALVD-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075C1044 +----AATFAALERAAGGRLGICAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETALNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ +ARADAKAKENVIAAAARIAVAAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria IOP40-10 TaxID=396596 RepID=B1FL89_9BURK +----ATSFAALEHAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EQPGLLQQRVTYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPVGSQVADKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ +ARADAKAKDDVIAAAARIAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=UPI000571A012 +-qRLQQEFARIELATTGRLGVAALDMETGLRA-SRRGDERFPMCSTFKAMASAAVLHRVD +RGESSLDQQIRFEAKDILANSPVTKEHVASGMTLAELCEAAITRSDNTAGNMILREIGGP +AGFTSFFRTIGDNVSRLDRWELALNEGVSGDPRDTTSPVAMLKDLQRVLLGDVLSAASRQ +KLIDWMVANKTGDARLRAGVPRDWRVADKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMEKCNEVIADVARAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1Z1VQJ7_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVIYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=E9LZM5_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLSHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A0U2T6D5_PROMI +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQSVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000978A2A6 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP +QAVTAYARSIGDATFRLDRREPELNTAPPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] class A beta-lactamase n=1 Tax=Bosea sp. 117 TaxID=1125973 RepID=UPI000493BAFE +-eALTASLRGIEAKTGGRLGVALIDGTDGAVE-GYREAERFPMCSTFKALAAAAVLARVD +AGSERIDRVVRYTRADLVTYSPAAEKHVDDGMTLDALCEAAVTLSDNTAGNLLLKAIGGP +AGLTAYARSLGDRLTRLDRWETALNEAAPGDERDTTTPAAMAGNLRRLVLGDALQPASRA +RLTGWLVGNKTGDTRLRAGVPGDWRVGDKTGTGENGTANDVGIAWPPRRAPLVVAIYLTQ +SRGDAASRNAAIAEAARAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=Q934I1_BURPE +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTT +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A4GWT3_KLEPN +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=A0A3N2SDD8_9ENTR +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIQAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAENRRDVLAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A235HDW6_AZOBR +--RLADAIAALEKRSGGRLGVAVLDTGTGQRF-GHRADERFPMCSTFKFLLAGAVLKRVD +DGRERLDRPIPVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFLRTLGDQKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRD +RLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLIASYLTE +TADGFKERDAIHAGVGRAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=Q8VN23_9ENTR +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SNKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIQAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDVLAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomallei (strain 1710b) TaxID=320372 RepID=Q3JFF0_BURP1 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomallei (strain K96243) TaxID=272560 RepID=UPI00032D6826 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum frisingense TaxID=92645 RepID=UPI0005876466 +--SIVQKLARLEADIGGRLGVSLVDTVHGRQW-GYRADERFPMCSTFKFLAAAAVLRRVD +EGRERLARRIVYRKQDLVPYSPTTGKHTGGALSMAQLCEAAITLSDNTAANLMLASMGGP +AGLTGFVRTQGDELTRLDRNEPTLNEAIPGDPRDTTTPAAMTADLRQVVLGNALAPASRE +QITQWLLANQTGDKRVRAGLPAGWKVGDKTGTGDRGTANDVGVVWTPQGAPLLFAVYLTE +NTAEAARRDAVHAEVGRLIAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia singularis TaxID=1503053 RepID=A0A118DPT1_9BURK +--DAQRALRELEASFDGRIGVAALDTATNAKI-AYRADERFAFCSTFKMMLSAAVLARSA +AEPDLLPRRIVYAKRDLVEYSPITGKHAGAGMTTAELCAAALQYSDNTAANLLISLLGGT +QAVTAYARSIGDAEFRLDRRETELNTAIPGDLRDTTTPSAMAASLRRLLLGDALGQAQRE +QLNAWMLGNTTGNERIRAGVPPAWRVADKTGTGDYGTANDIGVLYPPGRAPVVLAIYTTG +RAQQARARNDVIASAARIVARAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0P0IV60_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEHTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000753B7E5 +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTSRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVTWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ +ARADAKAKENVIAAAARIAVATf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q842S3_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYSPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2Z4BV97_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYSPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=Q939N4_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] UPI00144A4CA8 UniRef100 entry n=2 Tax=unknown TaxID=N/A RepID=UPI00144A4CA8 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTAPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia pseudomallei TaxID=28450 RepID=B1H5V3_BURPE +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=4 Tax=Burkholderia pseudomallei TaxID=28450 RepID=A8ELB7_BURPE +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0007621BEF +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVTWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ +ARADAKAKENVVAAAARIAVATf +>[subseq from] CTX-M-14 Class A Beta-Lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0005D2D2AF +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTAPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=29 Tax=Enterobacterales TaxID=91347 RepID=Q9L5C8_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Pseudomonas TaxID=2583993 RepID=A0A081Y9J5_9PSED +--STLERLQQLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACVLARVD +RGEEQLARRIVYSQADLVEYSPASERHVGQPMSVAELCEAAITLSDNGAANLLLASLGGP +SGLTDWLRSTGDNVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDVLQAASRD +QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG +SPAPAEKRDALLAEVGRLA---- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZW7_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTDGw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q5MAF8_KLEPN +-nAVQQKLAALEKSSGGRLGVPLIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium manausense TaxID=989370 RepID=A0A0R3DZN2_9BRAD +-----EAIKQLEQKSGGRLGVSVLDTNSGVPI-HHRGDERFPMCSTFKVLAAAAILKDVG +SKLEGLERRVRIEQADLVEYSPVTSKHVGGEMSLRELCEAAITLSDNTAGNALLKNIGGP +AGLTSFARSLGDETTRLDRIETELNEAAPGDPRDTTTPNAMAANFRRLLLGDALVPEGRD +QLIKWLVANKTGDSRLRAGLPQGWRVGDKTGSGQRETANDVAIVWPPERSPIIIAVYLTG +ASLDPNGRNDVIASVGREVGKAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=H7CHS5_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEATLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase Toho-1 n=3 Tax=Escherichia coli TaxID=562 RepID=UPI0001B04C53 +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTAPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAENRNDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=E0AF02_KLEPN +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=F1DTB3_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDRTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRHDVLASAARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=UPI00119DB802 +-kRLADAIAALERRSGGRLGVAVLDTGTGQRF-GHRADERFPMCSTFKFLLAGAILKRVD +EGRERLDRHIPVTKADLVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRD +RLVAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE +TADSFKERDAIHAGVARAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A0N7I8Z4_AZOBR +-kRLAGAIAALEKRSGGRLGVAVLDTGTGQSF-GHRADERFAMCSTFKFLLAGAILKQVD +EGRERLDRRIPVSKADMVPYAPFVETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRD +QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLIASYLTE +TPDSFKERDAIHAGVARAVAD-- +>[subseq from] Beta-lactamase LUT-3 n=1 Tax=Pseudomonas luteola TaxID=47886 RepID=C0LNZ9_PSELU +--SFQDRLAKLEQKLNGRLGVCAIDTANGAQL-GYRANERFAMNSTFKVMLASAFLARSQ +DEPGLLEERLMYTRADLVTYSPVTEKHVSTGMTVAELCAAGIQYSDNTAANVLMKKLGGP +EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTSTPQAMAMSLQRLALGDMLAADKQH +QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRRAPVVLALYSAL +ENQQAEARNDVLADAARIVAE-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000977F335 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRITARAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas TaxID=1073 RepID=UPI00115DF2E5 +--AIAARFAELEARSGGRLGVCVLDSSNGRMI-GHRLDERFPMCSTFKVLAAGLVLARVD +RKQESLDRRVSYTKSDLVTYSPATETRVEGGMTIAELCEAAITLSDNTAGNLLLGSFGGP +AGLTAFARSLGDQTTRLDRIETELNEALPGDARDTTSPRAIAQDLHALALGDALTPSSRA +LLVGWMKANTTGGARIRAGVPSGWSVADKTGTGERGTANDIAVLWPPQRAPLIVTVYLTG +ATVSRDQQNRLIAAAGAEA---- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. PI1 TaxID=1582493 RepID=UPI0005B9DD60 +--STLERLQQLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACVLARVD +RGEEQLARRIVYSQADLVEYSPASERHVGQPMSVAELCEAAITLSDNGAANLLLASLGGP +SGLTDWLRSTGDNVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDVLQAASRD +QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG +SPAPAEKRDALLAEVGRLA---- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00087267AC +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKLLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAXLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L053_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIRAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=B6E9R9_SALET +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTPAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q5MAF9_KLEPN +--AVQQKLAALEKSSGGRLGVPLIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Collimonas fungivorans (strain Ter331) TaxID=1005048 RepID=G0AJJ5_COLFT +----AGQLRQIEAKSGGRLGVAILDTVTGQSH-SYRGDERFPMCSTFKLLAAGLTLHRVD +QGREQLARRIRFEKADLVPYSPATEKHAGGDMSVAELCEATLTLSDNTAANLLLHSFGGP +PQLTAYLRSLGDKVTRLDRIEPDLNQATPGDPRDTTSPSAMLSTMQQLLLGNALSADSRK +QLTTWLLANKTGDKRLRALLPAGWRVGDKTGSGAYGSTNDIGMLFPPGRAPLLVAAYLTG +TKASEATRNATLAEVGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Edaphovirga cremea TaxID=2267246 RepID=UPI000DF01D96 +--EIQQKLADLEKSSGGRLGVALINTADNSRI-VYRGDERFPMCSTSKVMAASAVLKQSE +TQKDVLNQRVKISKSDLVNYNPITEKHLDTGMTLGELSAATLQYSDNTAMNKLITHLGGT +QGVTAFARSIGDKTFRLDRTEPELNTAIPGDERDTSTPLAMAESLRKLTLGDALAKPQRA +QLVEWLKGNTTGAASIRAGLPETWVVGDKTGSGDYGTTNDIAIIWPTNKAPLILVTYFTQ +TEQNAKSRKDVLADAARIVTQ-- +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=S0F1K6_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas palustris TaxID=1076 RepID=UPI000641F99A +--AIAARFAELEARSGGRLGVCVLDSSNGRMI-GHRLDERFPMCSTFKVLAAGLVLARVD +RKQESLDRRVSYTKSDLVTYSPATETRVEGGMTIAELCEAAITLSDNTASNLLLGSFGGP +AGLTAFARSLGDQTTRLDRIETELNEALPGDARDTTSPRAIAQDLHALALGDALTPSSRA +LLVAWMKANTTGGARIRAGVPSGWNVADKTGTGERGTANDIAVLWPPQRAPLIVTVYLTG +ATVSRDQQNRLIAAAGAEA---- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. KJ006 TaxID=416344 RepID=I2DXP2_9BURK +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETALNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ +ARADAKAKENVIAAAARIAVAAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=G0XMH2_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTQNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000F05A0E5 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSV +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0005D8B0F4 +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETALNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ +ARADAKAKENVIAAAARIAVATf +>[subseq from] Beta-lactamase n=1 Tax=Skermanella stibiiresistens SB22 TaxID=1385369 RepID=W9GWJ4_9PROT +-----ADLARIETGISGRLGVAVHDTGTGRRL-EYRSGQRFPMCSTFKVVASAALLTRVD +AGREKLDRRIRFGAGDLVTYSPVTKDRVGGDMTLAELCEAGITQSDNTAANLLLANIGGP +AGMTEYARSLGDAMTRLDRIETELNESTPGDPRDTTTPAAMTETLRKLVLGDALSPASRD +HLAAWLVANKTGDARLRAGVPKDWRVGDKTGSGDHGTANDIGVFWPPGRAPLVVSVYLTE +TKASMDDRSAAIAAVARVVT--- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0003C0A7A9 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +SEPALLQRRIAYAKGDLIRYSPIIEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Cupriavidus basilensis TaxID=68895 RepID=A0A0C4YHK8_9BURK +--AAQDRLAALELAAGGRLGIAALNTANGARL-SHRANERFALCSTFKVIAASAVLQRSA +TQAGLLQRRITYKKDELVAYSPITEKHVGGGLTVAELCAAALQYSDNTAANLLMKLLGGP +AAVAAFARTIGDDQFRLDRWETELNTALPGDPRDTSTPAAMAASLQRLTLGDALGGVERE +QLVAWMRGNTTGATRIRAGVPVDWQVADKTGTGDYGTANDIGVAWPPGKPPIVLAIYFTQ +PGKDTAYRNDVLASAARIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1Q1MQ16_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPITEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=UPI0003A98B5D +-kRLAGAIAALEKRSGGRLGVAVLDTGTGQSF-GHRADERFAMCSTFKFLLAGAILKQVD +EGRERLDRRIPVSKADMVPYAPFVETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRD +QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLIASYLTE +TPDSFKERDAIHAGVARAVAD-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075C0533 +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKTMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETEVNTALPGDLRDTTTPAAMAASIRALTLGDALPAAQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ +ARADAKAKENVIAAAARIAVAAf +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A060DLH1_AZOBR +-kQLADAIAALEKRSGGRLGVAVLDTGTGQCF-GHRADERFPMCSTFKFLLAGAVLKRVD +EGRERLDRTIPVTKADMVPYAPFAETRLGGPPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRE +RLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE +TADTFKERDATHAGVARAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Collimonas fungivorans TaxID=158899 RepID=A0A419U0J9_9BURK +---VARQLRQIEAKSGGRLGVAILDTVTGQSH-AYRGDERFPMCSTFKLLAAGLTLHRVD +QGREQLARRIRFEKADLVPYSPATEKHVGGDMSVAELCEAPLTLSDNTAANLLLHSFGGP +PRLTAYLRSLGDKVTRLDRIEPDLNQATPGDPRDTTSPNAMLSTMQQLLLGNALSADSRK +QLTTWLLANKTGDKRLRALLPAGWRVGDKTGSGGYGSTNDIGMLFPPGRAPLLVATYLTG +TKASEATRNATLAEVGRLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A4D8QHC2_AZOBR +-kRLADAIAALEKRSGGRLGVAVLDTGTGQSF-GHRADERFPMCSTFKFLLAGAVLKRVD +EGRERLDRPIPVTKADMVPYAPFAETRLDGLPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGNALTPASRE +QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE +TPDTFKERDATHAGVARAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q0GM96_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTQAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas heilongjiangensis TaxID=1387883 RepID=A0A2N7TJF2_9GAMM +---LTDKVIEIEERLGARIGVAVLDTQTGHRW-EHRGNERFPMSSTFKTLACGAVLARVD +TGEEALDRRIRFAAGDVVTYSPVTEHRVGGDMTLAELCEATITTSDNTAGNLILETLGGP +GGLTEFMRSLGDTTTRLDRWETELNEATPGDPRDTTTPVAMADSLHALLFEERLSPSSRD +QLAAWLVANTTGDAKLRAGLPRNWRIGDKTGGGGHGTNNDVAVIWPPDREPAIVSVYLTE +SEASFDDRNAAIAEIGRLVK--- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000F06407E +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTAM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=13 Tax=Proteobacteria TaxID=1224 RepID=H6V563_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacter cloacae TaxID=550 RepID=C5MRF5_ENTCL +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTETTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDDB361 +--SLEAAFKELEKATGARLGVSAHDTGSGKRI-DYREKELFAMCSTFKFFAAAAILARVD +QKKEQLDRIVTYKKSDLVDYSPVTEKHVGEGMSLAAICEAAITYSDNTAGNLMLDALGGS +KGLTDYARSLGDTITRLDRRETELNEATPGDPRDTTTPAAMRENLEKTVLGTALSEQSRK +QLADWLIGNKVGDKRLRAGLPKDWKVGDKTGTSDSGMANDVAVIWPPDRKPIVLTVYLYD +PKGTADSRNAIHQKVASLIAEH- +>[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=Q8RKB1_9ENTR +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWGVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PEQKAESRRDVLAAAAKIVTHGf +>[subseq from] Beta-lactamase n=7 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A223B3Y7_ECOLX +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWGVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PEQKAESRRDVLAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q5MAG2_ECOLX +--AVQQKLAALEKSSGRRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=F1CLM9_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELIAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. Y2R2 TaxID=2562282 RepID=A0A5C1NN05_9GAMM +-dELSRALEDTEARLGARLGVSILDTETGKLW-QHRNDERFPLNSTFKALASAAVLARVD +AGEEDLDRRITFTESDLVDWSPVTEKHVGDEMTLGELCQAALQWSDNSAANLVLDAIGGP +QGLTEYMRTLGDDVTRLDRWETELNEGTPGDPRDTSTPEAMRQSLQKVLLGEALSAESRQ +QLEDWMLGDKVADDLLRAAIPQDWRIADKTGAGGYGSRNIVAVIWPPQRQPVIAAIYITE +TEASMDESNVAIADIGRALVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Chimaeribacter arupi TaxID=2060066 RepID=A0A2N5ENL6_9GAMM +-dTLTAQLAELERNANGRLGVALIDTGSQREI-TYRGEERFAMASTFKVLAAGAVLQRSV +TQPALLEKRIRYDRAALQSYAPVTGKHLAGGMTVAELCAAAIEWSDNTAANLLLTEIGGP +QSITKLARSLGDDKTRLDRWEPELNTAIPGDERDTSTPRAMARNLQHLALGEALPQAQQQ +QLIGWLKNSQTGAKSIRAGVPAGWDVGDKTGSGDYGTTNDLAVIWPPHGKPLVLAIYFTQ +PKADAEARRDVLATATRLVLASf +>[subseq from] class A beta-lactamase n=1 Tax=Chimaeribacter arupi TaxID=2060066 RepID=UPI000C7D9850 +-dTLTAQLAELERSANGRLGVALIDTGSQREI-TYRGEERFAMASTFKVLAAGAVLQRSV +TQPALLEKRIRYDRAALQSYAPVTGKHLAGGMTVAELCAAAIEWSDNTAANLLLTEIGGP +QSITKLARSLGDDKTRLDRWEPELNTAIPGDERDTSTPRAMARNLQHLALGEALPQAQQQ +QLIGWLKNSQTGAKSIRAGVPAGWDVGDKTGSGDYGTTNDLAVIWPPHGKPLVLAIYFTQ +PKADAEARRDVLATATRLVLASf +>[subseq from] class A beta-lactamase n=1 Tax=Azohydromonas lata TaxID=45677 RepID=UPI00082ABC71 +--ALTRALPALEQRLGGRLGVYVLDTQSGRQW-TWRADERFPMCSTFKVLACGAVLARVD +AGEEALGRRIRFKAEDLVTYSPVTELHASGDMPLGALCEAAMTRSDNTAANLILRSLGGP +AAVTAFARTLGDPATRLDRWETALNEARPGDPRDTTTPAAIGRNLRALLLGPHLAPASRE +QLARWLQANRTGDARLRAGLPAAWRVGDKTGSGDFGTSNDVAVIWPPGRAPVIASVYVTE +CGAAFEDRNAAIADVARAL---- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium erythrophlei TaxID=1437360 RepID=A0A1H4WJF5_9BRAD +-rQLQEEFARIELATSGRLGVAALDMETGLRA-SQRGDERFPMCSTFKALASAAMLHRVD +RGESSLDQRVQVEAKDILAYAPVAKQHVGSSMTLSELCEAAITLSDNTAANLLLREIGGP +AGFTSFFRTIGDNVSRLDRWEVALNEAVPGDPRDTTSPVAMLKSLQRVVIGDVLQAASRQ +KLVDWMVANKTGDARLRAGVPRDWKVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMEKCNEVIANVARAVAH-- +>[subseq from] Beta-lactamase n=11 Tax=pseudomallei group TaxID=111527 RepID=H9CTS3_BURPE +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=I0DH95_ECOLX +--AVQQKLAALEKSSEGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKLSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria MEX-5 TaxID=396597 RepID=B1T356_9BURK +----ATSFAALEHAAGGRLGVCAIDAASGRRA-QHRADERFPFCSTFKAMLSAAVLAHSV +ERPGLLQQRVTYGQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QLVAWLRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ +ARADAKPKDDVIAAAARIAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=E9LZM4_ECOLX +--AVRQKLAALEKSSGGRQGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=A0A1W5RXG1_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPITEKHVNGTMTLAELSAAALQYTDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000841F2B4 +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNYSPVSGRHVATGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTSYARSIRDDTFRLDRWETALNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ +ARADAKAKENVIAAAARIAVAAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5D8SME3_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHXNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAXRRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase LUT-6 n=1 Tax=Pseudomonas luteola TaxID=47886 RepID=C0LP02_PSELU +--SFQDRLAKLEQKLNGRLGVCAIDTADGAQL-GYRANERFAMNSTFKVMLASAFLARSQ +DEPGLLEERLTYTRADLVTYSPVTEKHVSTGMTVAELCAAGIQYSDNTAANVLMKKLGGP +EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTSTPQAMAMSLQRLALSDMLAADKQH +QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRRAPVVLALYSAL +ESQQAEARNDVLADAARIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Nitrobacter sp. 62-13 TaxID=1895797 RepID=A0A1Q3K7H5_9BRAD +--RFVEELKRLEGGSGGRLGVAMLDTGTGQCV-GHRMDERFPMCSTFKVLASGAVLHSVD +AGKESLARRIYFTDSDLVTHSPETQKHVGPVMTVAELCEAAMTLSDNTAGNLLLASIGGP +QGLTAFVRSLGDEVTRLDRIETELNEAAPDDLRDTTTPDAMAADLRALALGDVLSTKSRT +QLVSWLAANTTGSKRLRAGLPAGWRVGDKTGTGEQGTANDVAVIWPPDRAPFVITAYLTG +AAAPVERQDAVMAAVGRAVT--- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000F0705D2 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLERREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium uaiense TaxID=2594946 RepID=UPI0013B8E911 +-qRLQQEFARIELATTGRLGVAALDMETGLRA-SRRGDERFPMCSTFKAMASAAVLHRVD +RGESSLDQRVQVEAKDILVYAPVAKQHVGSSMTLSELCEAAITLSDNTAANLLLREIGGP +AGFTSFFRTIGDNVSRLDRREVELNEAVPGDPRDTTSPVAMLKDLQRVVLGDVLQPMSRQ +KLTDWMLANKTGDARLRAGLPRDWRVGDKTGSGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMDKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. ABCPW 14 TaxID=1637860 RepID=A0A132CES7_9BURK +--AAERQLGELESSFDGRLGFVALDTATGARI-AHRANERFPFCSTFKTMLSAAILARSA +GDATLLRRRIPYAKRDLVSYSPITEKRVGDGMTVAELCAAMLQYSDNTAANLLIALLGGP +QAVTAYARSIGDTTLRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGAAQRA +QLDTWMLGNTTGGARIRAGVPADWRVADKTGTGDYGTGNDIGVAYPPNRAPIVIVIYTTM +RDKNAQARDDVLASAARIAARTf +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000DD804EF +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPITEKHVNGTMTLAELSAAALQYTDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q3HLW4_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI001439BB01 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAXLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000EF21488 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0009765C3C +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP +QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] BETA-LACTAMASE n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0000110AD3 +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTAPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAERRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KT75_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAATVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTDGw +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q2XPY6_SALET +--DVQQKLAELEQQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVIYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Yersiniaceae TaxID=1903411 RepID=UPI00093367D9 +-dTLTAQLAELERNANGRLGVALIDTGSQREI-TYRGEERFAMASTFKVLAAGAVLQRSV +TQPALLEKRIRYDRAALQSYAPVTGKHLAEGMTVAELCAAAIEWSDNTAANLLLTEIGGP +QSITKLARSLGDDKTRLDRWEPELNTAIPGDERDTSTPRAMARNLQHLALGEALPQAQQQ +QLIGWLKNSQTGAKSIRAGVPAGWDVGDKTGSGDYGTTNDLAVIWPPHGKPLVLAIYFTQ +PKADAEARRDVLATATRLVLASf +>[subseq from] Beta-lactamase CTX-M-14 n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae (strain HS11286) TaxID=1125630 RepID=UPI000572ABBE +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCGTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Trinickia symbiotica TaxID=863227 RepID=A0A2N7X035_9BURK +----KTKLAAIEKQFGGRLGVYALDTGSGTEI-RHRADERFPFCSTFKMVLASAVLAKSV +QEPGLMEQRMQYAQSDLVSYSPISRKHVADGMTVAELCRAAVELSDNTAANQLIKLLGGP +AAVTAFARSIGDNTFRLDRWETELNTAIPGDPRDTTTSRAMAHTLQAVALGNALPETQRD +TLQTWLRGCQTGAKRIRAAVPAGWDVGDKTGTGDHGTANDVAVIWPPSRKPIVLAIYHTQ +EKPDTRGRDEAIADAARVVVA-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000F04F1D1 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTAM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=E3PQJ5_9ENTR +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAALLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIQAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDVLAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1Z3GWX3_KLEPN +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGIGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=V5N077_KLEPN +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001186BE4F +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIRAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD849D4 +--SLEAAFKELEKATGARLGVSAHDTGSGKRI-DYREKELFAMCSTFKFFAAAAILARVD +QKKEQLDRIVTYKKSDLVDYSPVTEKHVGEGMSLAAICEAAITYSDNTAGNLMLDALGGS +KGLTDYARSLGDTITRLDRRETELNEATPGDPRDTTTPAAMRENLEKTVLGTALSEQSRK +QLSDWLIGNKVGDKRLRAGLPKDWKVGDKTGTSDSGMANDVAVIWPPDRKPIVLTVYLYD +PKGTADSRNAIHQKVASLIAEH- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A345IT60_BURVI +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGGYGTTNDAGVVWLPSRAPIVLTVYYTQ +ARADAKAKENVIAAAARIAV--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas citronellolis TaxID=53408 RepID=A0A4Z0IKT2_9PSED +--STLERLKQLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACVLARVD +RGEEQLARRIVYSQADLVEYSPVSERHVGQPLSVAELCEAAITLSDNGAANLLLASLGGP +AGLTDWLRSTGDDISRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDILQPASRD +QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG +SPAPAEKREAVLAEVGRLA---- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTV9_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILATYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5P8NAT3_KLEPN +-eDVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=I3VNW5_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +AQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVDDKTGSGDYGTTNDIAVIWPQGRAPLALVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=UPI000E0C0F01 +-kRLADAIAALEKRSGGRLGVAVLDTGTGQRF-GQRADERFPMCSTFKFLLASAVLKRVD +EGRERLDRRIAVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRD +QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE +TPDSFKERDATHAGVARAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Shigella sp. SH202 TaxID=1074432 RepID=G3EPV9_9ENTR +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGQ +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000755DDCF +----AATFAALERAAGGRLGVCAIDTASGRRA-RHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNYSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETEVNTALPGDLRDTTTPAAMAASIRALTLGDASPPAQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ +ARADARAKDEVIAAAARIAVAAf +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=Q5KT52_ECOLX +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTESTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Class A beta-lactamase n=1 Tax=Trinickia symbiotica TaxID=863227 RepID=A0A2T3Y1E2_9BURK +---SRTKLAAIEKQFGGRLGVYALDTGSGTEI-RHRADERFPFCSTFKMVLASAVLAKSV +HEAGLMQRRIQYAQSDLVSYSPISGKHVADGMTVDELCRAAVELSDNTAANQLIKLLGGP +AAVTAFARSIGDKTFRLDRWETELNTAIPGDPRDTTTPTAMAHTLRAVALGNALPDMQRD +MLQTWLRGCQTGAKRIRAAVPAGWDVGDKTGTGDHGTANDIAVIWPPSRKPIVLAIYHTQ +EKPDTRGRDEAIADAARVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum sp. B65 TaxID=137708 RepID=UPI0003497D75 +--AISARLARLEADVGGRLGVSLVDTAGARQW-GYRADERFPMCSTFKWLAAAAVLRRVD +EGREQLTRRIVYHQRDLIPYSPTTGKHVGGTLSLAQLCEAAVTLSDNTAANLMLASMGGP +AGMTAFVRTLGDALTRLDRNEPALNQAVPGDPRDTTTPAAMTADLQRLVLGDALTPASRA +QLTQWLLANQTGDKRVRAGLPAGWKVGDKTGTGRLGTANDVGVVWTPQGKPLLFAVYLTE +NAADDARRDALHAEVGRLIAQ-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI00052AC912 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPLVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0005314B91 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPLVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3Q8EPK3_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDDTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAEHRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia sp. lig30 TaxID=1192124 RepID=A0A063B5R1_9BURK +----ANSFAELERAAGGRLGVCAIDTGSGRRA-QHRADERFPFCSTFKTMLGAAVLARSV +ERPALLQQRVTYGPGDLVRYSPVTEMHVGTGMTVAELCAAAIQYSDNSAANLLMKLIGGP +SGVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASVRALALGDALPAAQRA +RLVEWLCGNKVGDKRFRAGVPPGWQVGDKTGTGDYGTTNDAGVMWPPSRAPIVLAVYYTQ +ARADATAKDDVIASAARIAVAAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=UPI0005F591D3 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] UPI0011C3427D UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0011C3427D +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. CY15W TaxID=2692172 RepID=UPI00136D9D7A +----TAQLALLEKESGGRLGVAALNTGDGRQL-LHRADERFPVCSTFKMMLSAAVLARDP +---ALLKKRIPYEKSDLVPHAPITSKHVGEGMTVAELCEATLQYSDNPAANLLMKQLGGP +AAVTAYARSIGDSEFRLERWETELNTAIPGDPRDTTTPEAMARSLQKLVLGDALPPTQRK +QLKDWMLGNTTGATRIRAGVPPGWPVADKTGAGDYGTVNDIAVIWPPGKAPIVLAVYLTQ +PGKDDKSHPEIHGEVAKVVIEAf +>[subseq from] Beta-lactamase n=1 Tax=Collimonas sp. PA-H2 TaxID=1881062 RepID=A0A2A9K3V0_9BURK +--AIVEQLRQIEAKSGGRLGVAIFDSGSGQTY-AYRGGERFPMCSTFKLLASALVLKRVD +QGKEQLARRIRYQKADLVPYSPVTEQHTGAGMTVAELCEAAITQSDNTAANLLLHSFGGP +AQLTAYMRASGDKMTRLDRIEPHLNEAAPGDPRDTTTPSAMVSSLREILLGRNLSTSSRE +QLTDWLLANKTGDKRLRALLPAGWRVADKTGTGDQGTANDIGMLLPPGRAPLLVASYLTG +APAPAAARDAVHAQVGRLAA--- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia sp. BDU5 TaxID=1385590 RepID=UPI000758BCDB +--AAERQLGELESSFDGRLGFVALDTATGACI-AHRADERFPFCSTFKTMLSAAILARSA +GDATLLRRRIPYEKRDLVSYSPITEKHVGEGMTVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDTMFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGVAQRA +QLDTWMLGNTTGGARIRAGVPADWRVADKTGTGDYGTGNDIGVAYPPNRAPIVIVIYTTM +RDKNAQARNDVLASAARIAARTf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. BDU6 TaxID=1385591 RepID=A0A1B4FLI7_9BURK +--AAERQLGELESSFDGRLGFVALDTATGACI-AHRADERFPFCSTFKTMLSAAILARSA +GDATLLRRRIPYEKRDLVSYSPITEKHVGEGMTVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDTMFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGVAQRA +QLDTWMLGNTTGGARIRAGVPADWRVADKTGTGDYGTGNDIGVAYPPNRAPIVIVIYTTM +RDKNAQARNDVLASAARIAARTf +>[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=A0A2R3SK14_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAESIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A097BQW5_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPNAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2H4FXZ9_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDDTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0008A254D4 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNNNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Cy-637 TaxID=2608327 RepID=UPI00141E4CFF +--DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFPLCSTFKVVLVSAVLARAT +GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAHARSIGDATFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGGYGTANDVAVLYSPSRQPVVLTVYTTR +PDKDAKYDNAAIAAVARIVTATf +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI00053205A8 +--AAERQLRELESTFDGRLGFVAFDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ49_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A173GH11_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A060KQ56_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L009_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ03_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZD6_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZZ1_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L064_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A223A5R2_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia sp. ESBL358B15_13_3E TaxID=1563525 RepID=A0A0A0R195_9ESCH +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAAR------ +>[subseq from] Beta-lactamase CTX-M-14 n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae (strain HS11286) TaxID=1125630 RepID=UPI000572AB9D +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCGTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGAGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=Q6DQV0_ENTCL +--DVQQKLAELEQQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2S1T3S7_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L035_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. PBS-H4 TaxID=434008 RepID=UPI001315E90D +---LARQLAEIEKKIGGRLGVHVLDTANGRHA-GHREDERFALCSTFKFLAAALVLARVD +QGKERLDRRVVYSRDDLVTYSPATEKHAGTDMTMAQLCEAAVTLSDNTAGNLMLASFGGP +AGLTAFMRSLGDAHTRLDRIETALNEAREGDPRDTTTPAAMVASMQKILLGDALSTASRA +QLLQWLDDNKTGGQRIRAGVPADWKVGDKTGTGENGAANDIAILRPPGRSPILLSVYLTE +TRASIADRNAAHAAVAAAVA--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ62_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNAAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTNGw +>[subseq from] Beta-lactamase n=1 Tax=Rhodopseudomonas palustris (strain DX-1) TaxID=652103 RepID=E6VH66_RHOPX +--AIAARFAELEARSGGRLGVCVLDSSNGRMI-GHRLDERFPMCSTFKVLAAGLVLARVD +RKQESLDRRVSYTKSDLVTYSPATETRVEGGMTIAELCEAAITLSDNTAGNLLLGSFGGP +AGLTAFARSLGDQTTRLDRIETELNEALPGDARDTTSPRTIAQDLRALALGDALTPSSRA +LLVAWMKANTTGGARIRAGVPSGWIVADKTGTGERGTANDIAVLWPPQRAPLIVTVYLTG +ATVSRDQQNRLIAAAGAEA---- +>[subseq from] class A beta-lactamase n=1 Tax=Chimaeribacter arupi TaxID=2060066 RepID=UPI000C7BF24E +-dTLTAQLAELERNANGRLGVALIDTGSQREI-TYRGEERFAMASTFKVLAAGAVLQRSV +TQPALLEKRIRYDRAALQSYAPVTGKHLAEGMTVAELCAAAIEWSDNTAANLLLTEIGGP +QSITKLARSLGDDKTRLDRWEPELNTAIPGDERDTSTPRAMARNLQHLALGEALPQAQQQ +QLIGWLKNSQTGAKSIRAGVPAGWDVGDKTGSGDYGTTNDLAVIWPPHGKPLVLAIYFTQ +PKADAEARRDVLATATRLVLALf +>[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia sprentiae WSM5005 TaxID=754502 RepID=A0A1I9YU65_9BURK +--EAQRRLGALESATGGRLGVAALNTADGTQV-QHRADERFPFCSTFKVMAASAILKRSE +TENGLRRQHIAYTKDELVAYSPITAEHAGTGMTVSELCAAALQHSDNTAGNLLIKMLGGP +AAVTAFARSIGDDPFRLDRWETELNTAIPGDPRDTTTPAAMAGSLQRLALGDALGAPERA +MLIEWMRGNTTGAAKIRAGVPAAWSVADKTGGGDYGTTNDIAVMWPPGKPPIVLAVYFTQ +PDKDAPVRNDVVATAARIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTK6_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQV-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000C27EF6E +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTAM +RNPNAQARDDVIASATRIAARAf +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000976DA72 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFYSTFKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQF0_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVSYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Ap-962 TaxID=2608333 RepID=UPI00141F3E55 +--DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFPLCSTFKVVLVSAVLARAA +GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAHARSIGDATFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGGYGTANDVAVLYSPSRQPVVLTVYTTR +PDKDAKYDNAAIAAVARIVTATf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTQ9_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI000893E48E +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=Q8RLA1_BURPE +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRRESELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2R3SK19_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B4E8376 +--AVQQKLAALEKSSTGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTAPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. L27(2015) TaxID=1641858 RepID=UPI00131B1F60 +----TAQLATLEKNSGGRLGVTALDTANGMLI-RYRADERFPFCSTSKVMVAAAILERST +RQTGLMHKRIHYAKSDLVHYSPISEKHVADGMTVAELCAAAIQYSDNSSANLLMKILGGP +PAVTAFARSIGDKEFRLDRWETELNSAIPGDRRDTTTPAAMAISLRSLMLGDILPAAQRQ +QLQDWLRGNTTGANRIRAGVPADWRVGDKTGTGDYGTANDIAVLWPPARKPIVLTIYHTQ +LQTDAKPRDDVIAAATRIVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI00061C60C8 +-dALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALSPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARKDVLAGAAKIVASGy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ27_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHIGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=B2CR57_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTELTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. RA8 TaxID=662548 RepID=UPI0013186E7B +--DLARQFAGIEKKTGGRLGVHVLDTANGRRA-GHRQDERFAMCSTFKFLAAALVLARVD +QGKEKLDRRLTYSRQELAPHSPATEKHAGGDMTMAQLCEATITLSDNTAANLMLASFGGP +AGLTAYMRSLGDPHTRLDRIEPGLNEARAGDPRDTTTPAAMVGSMQKILLGDALSPGSRA +LLLQWLDDNKTGGERIRAGLPADWKVGDKTGTGENGAANDIAILRPPGRPPILLSVYLTE +TKASMADRNAAHAAVAAAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A159ZKX3_ECOLX +--DVQQRLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5P8NAV8_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00128E86B6 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=Kluyvera cryocrescens TaxID=580 RepID=Q8VVP3_KLUCR +--SVEQKLAALEQRSGGRLGVALIDTADGSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SQHDLLNQRIEIKKGDLTNYNPIAEKHVGGSMSLSELSAAALQYSDNVAMNKLIAQLGGP +QGVTAFARKIGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDAQRA +QLVTWMKGNTTGTASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLVLVTYFTQ +PQPEAESRRDVLASAAKIVTE-- +>[subseq from] class A extended-spectrum beta-lactamase KLUC-5 n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=UPI000C285D5D +--SVEQKLAALEQRSGGRLGVALIDTADGSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SQHDLLNQRIEIKKGDLTNYNPIAEKHVGGSMSLSELSAAALQYSDNVAMNKLIAQLGGP +QGVTAFARKIGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDAQRA +QLVTWMKGNTTGTASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLVLVTYFTQ +PQPEAESRRDVLASAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTK2_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0H4IS11_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A193H694_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L007_9BACT +--DVQQRLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A3B8DM63_9ENTR +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00123BE7BC +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1Q1MQ14_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=K9UTH3_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8G9E9_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ68_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQB4_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZA5_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZB3_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQC7_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A5JUR0_PROMI +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ75_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A0H4IVL4_KLEOX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZA9_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=33 Tax=Bacteria TaxID=2 RepID=Q6BBP7_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ89_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ07_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase Toho-1 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000D097FA4 +--SVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCATSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAENRNDILAAAAKIVTHGf +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F2BD9C8 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=25 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A2R3SK21_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp9142 TaxID=2184573 RepID=A0A3N8AJI1_9BURK +----ATSFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLAQSV +ARPGLLQQRVMVGQSDLVNYSPVSGKHVGTGMTVAALCEAAIQYSDNSAANLAMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPGAQRA +QLVAWLRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVIWLPSRAPIVLVVYYTQ +ARADAKAKDDVIAAAARIAVATf +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000F05815C +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPIAEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Rhizobiales bacterium 64-17 TaxID=1895814 RepID=A0A1Q4DJN8_9RHIZ +--SFTTTVRTLERRSGGRLGVAVIDTQSGKQS-GWRADERFPMCSTFKLVAAAAVLRRVD +RGAEQLDRRVVIRHRDIITYSPVTKERIGQAISIAELCEAAVTLSDNTAANLILKSLGGP +RAFTAFARSLGDHATRLDRIEPHLNSAIPGDRRDTTTPAAMAKTVRALVLGDALSAASRV +QLVAWLRGNKTGDTRLRAGLPDGWICGDKTGTGVRGTSNDIGVLWPPQQAPLVVTAYLTG +STGDAKARDAILADVARAVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=J7IB33_ECOLX +--SVEQKLAALEQRSGGRLGVALIDTADGSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SQHDLLNQRIEIKKGDLTNYNPIAEKHVGGSMSLSELSAAALQYSDNVAMNKLIAQLGGP +QGVTAFARKIGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDAQRA +QLVTWMKGNTTGTASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLVLVTYFTQ +PQPEAESRRDVLASAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=C5IUN2_ENTCL +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLALGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. TaxID=1890675 RepID=A0A2E7NXD3_9BURK +--ALTATLSRLEADIGGRLGVSLVDTAGGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD +EGKEQLARRIVYRQQDLVPYSPTTGKHTGGDLSLAQLCEAAITLSDNTAANLMLESMDGP +AGMTRFVRSLGDELTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ +QLAQWLVANQTGDKRVRAGLPKGWKVGDKTGTGRLGTANDVGVVWTEKGAPLLFAVYLTE +NAATDARRDAVHAEVGRLI---- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. DXTD-1 TaxID=2495592 RepID=A0A429WLF3_9BURK +--SAEAQLAALESSVGARLGVAALDTGSGARV-QHRATERFALCSTFKTMLAAAILARSA +RDSSLLERRVSYSRSDILTNSPITEKNLGQGMTVSALCAATMQYSDNAAANLLMKILGGP +AAVTAFARSIGDQTFRLDRWETELNSAIPGDLRDTTTPEAMAASLQRLVLGDALSAAQRS +QLEAWLLGNTTGAARIRAGVPADWKVGDKTGLGSYGTNNDTGVLWPPSGAPVVLAVYLTF +PKEDAPARNDVIASAARIVVN-- +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum huttiense TaxID=863372 RepID=A0A4P7AC91_9BURK +--ALTATLSRLEADIGGRLGVSLVDTAGGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD +EGKEQLARRIVYRQQDLVPYSPTTGKHTGGDLSLAQLCEAAITLSDNTAANLMLESMDGP +AGMTRFVRSLGDELTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ +QLAQWLVANQTGDKRVRAGLPKGWKVGDKTGTGRLGTANDVGVVWTEKGAPLLFAVYLTE +NAATDARRDAVHAEVGRLI---- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI00111D507D +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAGMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQE2_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVAWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L001_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAKSRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=A0A2S9KVM2_9BURK +----ATSFAALEHAAGGRLGVCAIDTASGRHA-QHRADERFPFCSTFKAMLGAAVLARSV +EQPGLLQQRVTYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPSAQRA +QFVAWLRGNKVGDKRIRAGVPAGSQVGDKTGTGGYGTTNDAGVIWLPSRAPIVLAVYYTQ +ARADAKAKDDVIAAAARIAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0S1LLA5_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPSLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A8W9A7_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTL3_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPSLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A2H5BF61_PSEAI +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPSLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C337F0C +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLQKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0P0HZ66_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGNSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp9031 TaxID=2184566 RepID=A0A3P0MST6_9BURK +-----TSFVALERAAGGRLGVCAIDTASGRRA-QHRASERFPFCSTFKAMLGAAVLAQSV +ERPGLLQQRVMIGQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPSAQRA +QLVAWLRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVIWLPSRAPIVLVVYYTQ +TRADAKAKDDVIAAAARIAVATf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=U3N3M8_ECOLX +--NVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] LUT family class A beta-lactamase n=1 Tax=Pseudomonas sp. LTJR-52 TaxID=2479392 RepID=A0A3G2NCV6_9PSED +--SFQDRLAKLEQKLNGRLGVCAIDTADGAQL-GYRANERFAMNSTFKVMLASAFLARSQ +DEPGLLEERLTYTRADLVTYSPVTEKHVVTGMTVAELCAAGIQYSDNTAANMLMKKLGGP +EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTNTPQAMAMSLQRLALGDMLAADKQH +QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRHAPVVLALYSAL +ENPQAEARNDVLADAARIVAE-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI00050F52B9 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGL +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q83ZQ7_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0001C05CC7 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=Q66W71_KLEPN +--DVQQKLAELEQQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZY9_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. FT80W TaxID=2666084 RepID=UPI0012B0D30A +-----AQLARLEQESGGRLGVAALNTADGRQV-LHRGDDRFPFCSTFKMMLAAAVLAREP +---SLLKRRIQYEKSDLVPHSPVTGKHVADGMTVAELCEATLQYSDNAAANLLMKQIGGP +AAVTAFARSIGDNEFRQERWETELNSALPGDTRDTTTPLAMARSLQKLVLGEALPQASRR +QLKDWMVGNTTGNARIRAGVPAGCLVADKTGAGDYGTVNDIAVIWPPGRAPIVLAVYLTQ +PGKDDKGRGDIHAEVAKVVIEAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Salmonella infantis TaxID=595 RepID=C3VMM9_SALIN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRHDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=Herbaspirillum TaxID=963 RepID=A0A495Q0T5_9BURK +--ALTATLSRLEADIGGRLGVSLVDTAGGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD +EGKEQLARRIVYRQQDLVPYSPTTGKHTGGDLSLAQLCEAAITLSDNTAANLMLESMDGP +AGMTRFVRSLGDDLTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ +QLAQWLVANQTGDKRVRAGLPKGWKVGDKTGTGRLGTANDVGVVWTEKGAPLLFAVYLTE +NAATDARRDAVHAEVGRLI---- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0009776230 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRREPELNTAPPGDERDTTTPAAMAASVHRLRVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Class A extended-spectrum beta-lactamase CTX-M-154 n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A650DI89_KLEPN +--DVQQKLAKLERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTW6_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDILASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Duganella sp. DN04 TaxID=2561932 RepID=A0A4Y9SJK4_9BURK +-------LARLEQECGGRLGVAALNTGDGRQL-LHRADERFPMCSTFKMMASAAVLARDP +---ALLKKRIRYDKADLVPHAPVTGKHVGEGMTVAELCEATLQYSDNPAANLLMKELGGP +AAVTAFARGIGDTDFRLERWETELNSAIPGDPRDTTTPLAMAKSLHKLVLGDALPPPARK +QLKDWMLGNTTGAARIRAGVPSGWPVADKTGAGDYGTVNDIAILWPPGKAPIVLAVYVTQ +PGKDDKAHPEVHGEVAKIVIEAf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ24_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDILASAAKIVTD-- +>[subseq from] Beta-lactamase CTX-M-14 n=2 Tax=Klebsiella pneumoniae subsp. pneumoniae (strain HS11286) TaxID=1125630 RepID=UPI000572AB9F +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCGTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGAGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRADVLASAARIIAE-- +>[subseq from] Beta-lactamase n=668 Tax=root TaxID=1 RepID=C7S9T0_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] UPI00126783C6 UniRef100 entry n=2 Tax=unknown TaxID=N/A RepID=UPI00126783C6 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYTDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella sp. ARS06-441 TaxID=474576 RepID=A8IW71_9ENTR +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDDTFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L043_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGATNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTC7_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWDVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL05_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas humi TaxID=1826671 RepID=UPI000853BF7E +--STLERLQQLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACILARVD +RGEEQLARRIVYGQADLVEYSPVSERHVGQPMSVAELCEAAITLSDNGAANLLLASLGGP +AGLTDWLRSTGDDVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDILQPASRD +QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDLAILRPPGRSPILVAAYLTG +SPAPAEKRDALLAEVGRLA---- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI00050F99D3 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAEVCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=Q0Z958_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPSLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDILASAAKIVTD-- +>[subseq from] Beta-lactamase n=3 Tax=Klebsiella TaxID=570 RepID=Q6ZXB6_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPSLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDILASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZB6_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=Q75NB4_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000D0F40D4 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGAETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. CCM 8692 TaxID=2607910 RepID=UPI00141DC001 +--EAQAELVALEAAAGGRLGVGAIDTGDGRRL-GHRADERFPMCSTFKAIAAAAILAHGK +NVPGWLDQRVRYTKADLVTYSPITEKHLDDGMTVGELCAATIQYSDNAAANLLMAKIGGP +GGVTGFARSMGDTVFRLDRWETELNTAIPGDPRDTTTPAAMAALLRRVALDDGLPAAQRD +QLQNWMRGNTTGAARIRAAVPASWAVADKTGTGAYGSSNDIGIVFPPKGAPVVLALYYTQ +ADAQAKANSDILAQATRIVMAAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A2Z4Q2E9_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRHVLASAAKIVTD-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia sp. R10 TaxID=2082624 RepID=UPI000D03C4D9 +--DVQQKLAELERQSGGRLGVALINTADNSQL-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L046_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL25_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL06_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia pseudomallei TaxID=28450 RepID=A0A0E1UDG8_BURPE +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGL +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0009786D27 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP +QAVTAYARSIGDATFRLDRRESELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=11 Tax=Enterobacteriaceae TaxID=543 RepID=Q845L5_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTQ6_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L004_9BACT +--DVQQKLAELERQSGGRLGVALINTAGNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ83_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKESDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=7 Tax=Bacteria TaxID=2 RepID=B0LV41_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum seropedicae TaxID=964 RepID=UPI0008481BFC +--ALTARLSRLEADIGGRLGVSLLDTASGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD +QGQEQLTRRIVYQKQDLVPYSPTTGKHTGGALSMAQLCEAAMTLSDNTAANLMLASMGGP +AGLTRFVRTLGDELTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ +QLTQWLIANQTGAKRVRAGLPASWKVGDKTGTGRLGTANDIGVVWTAQGAPLLFAVYLTE +NAATDAGRDAVHAEVGRLI---- +>[subseq from] Beta-lactamase n=2 Tax=Halomonas elongata TaxID=2746 RepID=E1V6J8_HALED +---LEAELASLEQRLDARLGVAVTDTGSGRHW-GHREDERFPMASTFKVLACAALLDRVD +AGQEELQRRVIYEQDDLVTYSPVTKEHVGEPMTLGSLCEAAMGYSDNSAANMVLKAIGGP +SAVTDFTRSLGDDMTRLDRWETKLNEAIPGDPRDTTTPAAMAADLQALFLGDRLSEESRE +RLTDWFLGNRTGDARLRAGLPDDWRIGDRTGSGAHGSTNNVAVAWPSDGEPVIISAYLTE +FEGDMDQRNAAIAEVGKLVAR-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ63_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGAMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ96_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASATKIVTD-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00123BFF3F +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PPPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum rubrisubalbicans TaxID=80842 RepID=A0A328IZU6_9BURK +--AISARLARLEADVGGRLGVSLVDTAGARQW-GYRADERFPMCSTFKWLAAAALLRRVD +EGREQLTRRIVYHQRDLIPYSPTTGKHVGGTLSLAQLCEAAVTLSDNTAANLMLASMGGP +AGMTAFVRTLGDALTRLDRNEPALNQAVPGDPRDTTTPAAMTADLQRLVLGDALTPASRA +QLTQWLLANQTGDKRVRAGLPAGWKVGDKTGTGRLGTANDVGVVWTPQGKPLLFAVYLTE +NAADDARRDALHAEVGRLIAQ-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2BF5B6 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAYVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000994A0FA +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGPMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A5B8KR99_ENTCL +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAANIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WYA8_9BACT +-eQFATELQRLERDSGGRLGVVLLDTATGKRA-GHRMDERFPMCSTFKVLAASAILHNVD +AGKESLERRVYFNETDLVTYSPETKKHVGPSMTIAELCKAAITLSDNTAGNLLLASIGGP +KGFTDFARSLGDKMTRLDRIETALNEALPDDPRDTTTPNAMASDLQSLVLGKTLSAKSRA +QLVEWLAANTTGGKRLRAGLPTGWHVGDKTGTGDRGTANDIAVIWPTGRAPVIVTVYLTG +ATASADQQSAVIAGVGRAV---- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00132F8656 +--AVQQKMAAREKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0009266322 +----QQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKFIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPADPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAEHRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A8BHZ3_ENTCL +--SVEQKLAALEQRSGGRLGVALIDTADGSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SQHDLLNQRIEIKKGDLTNYNPIAEKHVGRSMSLSELSAAALQYSDNVAMNKLIAQLGGP +QGVTAFARKIGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDAQRA +QLVTWMKGNTTGTASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLVLVTYFTQ +PQPEAESRRDVLASAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KT87_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVSGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. TSH20 TaxID=652754 RepID=A0A2U1WWS0_9PROT +--ALAGKMTELEARSGGRLGVAVLDTANGKLH-GWRGDERFPMCSTFKFLLAAAVLKAVD +QGKDRLDRRIPVTKADLVPYAPFAETRLNGTPTVAELCEAAMTLSDNVAANLLLPGIGNP +AGLTAFMRGIGDKTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMERILVGDVLRPDSRR +QLIDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAIVWPEGRAPLLVACYLTQ +TAEGFKQQDSIHAEVARAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=A0A2S9P045_9BURK +----ATSFAALEHAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLAHSV +ERPGLLQQRVTYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QFVAWLRGNKVGDKRIRAGVPAGSQVGDKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ +ARADAKPKDDVIAAAARIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=UPI0013FDC1CD +----ATSFAALEHAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLAHSV +ERPGLLQQRVTYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QFVAWLRGNKVGDKRIRAGVPAGSQVGDKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ +ARADAKPKDDVIAAAARIAVA-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001073F173 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAERRRDVLASAAKIVTD-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000A1DFC96 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRASIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A482GLY3_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPTSWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium paxllaeri TaxID=190148 RepID=UPI0011478E8E +-qRLIDEIKRLERESGGRLGVCVLDTATGARH-VHRGDERFPMCSTFKALAAAAILARVD +AGKEQLTRRITFEASALVTYSPVTEKHVGGDMTLAEICEAAVTLSDNTAGNLLLAALGGP +PGLTAFARSLGDQVTRLDRNEPSLNEALPDDPRDTTTPNAMASSLQALVVGTALSAPSRE +QLTAWLVANKTGDTRLRAGLPKDWRVGDKTGTGARGTNNDVAVIWPHGKAPIVITGYLTG +ATVPAAQQNAVWASVARAVS--- +>[subseq from] Uncharacterized protein n=1 Tax=Glaciimonas sp. PCH181 TaxID=2133943 RepID=A0A2T6F253_9BURK +--SAQMQLAALETQTGDRLGVHAINTADGGQL-GHRADERFPFCSTFKVLAISAILARSA +HEDGLLQQRIHYSPSEMVSYSPITERHVADGMTIAELCAAALQYSDNTAANLLIKALGSP +ASVTAFARTIGDNTFRLDRWETALNSAIPGDPRDTTTPAAMAHSLQRLALGDGLAPPQRA +QLQQWLQGNTTGAKRIRAGVPADWQVGDKTGSGDYGATNDVAVLWPPGKPPIIVALYFTQ +REKEAKSREDVLASAARIVVKAf +>[subseq from] Beta-lactamase n=4 Tax=Bacteria TaxID=2 RepID=A2TLT3_SALTM +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=bacterium TaxID=1869227 RepID=A0A4Q5NQR5_9BACT +--AARAQLGQLEKRFGGRIRVFALNTADGSGL-SYRADERFPVCSTFKVLAAAALLRKSG +RVPGLMQQRIKYQQGNLVSHSPITEKHVSGGMTVAELCAAAIQYSDNTAGNLMLRMLGGP +SALTAFSRSIGDSQFRLDRWETALNTAIPGDSRDTSTPRAMALNLERLVLGDALKSQQRK +QLREWMLGNTTGTKRIKAGLPANWLIGDKTGGGDYGTANDVGVLWPPHRKPIIVAIYTTQ +PKKDATAQNEVIADVARIVVK-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ67_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGAMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQC0_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQM-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI00052A4BEB +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYSPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6D1LUJ3_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A0P0GRE4_PROMI +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSCDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=3 Tax=Enterobacterales TaxID=91347 RepID=A0A2U9NK71_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSCGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ60_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAERHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. MHTC-1 TaxID=2495593 RepID=A0A3R9ZDQ1_9BURK +--ALSKQLADIEKASGGRLGVGVLDTGNGRRA-GHREDERFPLCSTFKFLAAAFVLARVD +QRKERLERRVVYGPRDLVTHSPVTEKHADGTMTVAQLCEATLTLSDNTAANLLLQSFGGP +KGLTAFMRSIGDAKTRLDRFETALNEARPGDLRDTTTPAAMSRSMQKILLGDILTQPSRA +QLLQWLDGNKTGDERIRAGLPADWKVGDRTGSGQNGTTNDIAILRPPGRAPILLSVYLTE +TAAAPAARNAALASVAAAVA--- +>[subseq from] class A extended-spectrum beta-lactamase CTX-M-226 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0010A73CF3 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A0K0TQJ3_PROMI +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A127R6W9_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=60 Tax=Bacteria TaxID=2 RepID=Q0GA57_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium guangzhouense TaxID=1325095 RepID=UPI001009EB2B +--QLIEAFEQLELKSAGRLGVSVLDTTTGAQI-HHRGDERFPMCSTFKVLAAAAILKGVG +SKLEGLERRVRIEQADLVEYSPVTSKHVGGDMSLRELCEAAITMSDNTAGNALLKNIGGP +AGLTSFARSLGDKTTRLDRIETELNEATPGDPRDTTTPNAMATNFRRLLLGDVLLTEGRD +QLGKWLIANKTGDSRLRAGVPKGWRVGDKTGAGEHGTTNDVAIVWPPERSPVIIAVYLTG +SALDPNGRNDVIASVGSAVAK-- +>[subseq from] UPI00144A4CB9 UniRef100 entry n=2 Tax=unknown TaxID=N/A RepID=UPI00144A4CB9 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTASTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=S6FS81_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGNGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075803D1 +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRVLTLGDALPAAQRA +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPILLTVYYTQ +ARADAKAKENVIAAAARIAVAAf +>[subseq from] class A beta-lactamase n=1 Tax=Duganella ginsengisoli TaxID=1462440 RepID=UPI0012D4AAB8 +-qSATDKLAALEKSAGGRLGVAVLDTGSGRQV-LHRADERFAFCSTFKTMVAAAILARSE +KEPDLLARRIRYTQADLVTYSPETEEHVKDGMTVAELCEATIQVSDNSAANLLMKVLGGP +PAVTAYARSIGDQQFRLDRWETELNSAIPGDTRDTTTPAAMMQSVNRLLLGDALAAPQRK +QLVDWMVGTLTGNERIRAGSPAGATVADKTGTGAYGVTNDIGVVWPQGRAPLVVVVYYAG +PDKDSKARSDVVATATKIALD-- +>[subseq from] class A extended-spectrum beta-lactamase CTX-M-234 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00140EA5CE +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFPMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELSAAALQYTDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ38_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIEKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B4E8374 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTASTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000DDD15F7 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLALGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sp. SH361 TaxID=1074437 RepID=G3EPW4_9ENTR +--DVQQKLAELERQSGGRLGVALINTADNSRI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVT--- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001185F320 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWLKGNTTGAASIRAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A8D3A8_KLEPN +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLEQSE +TQKQLLNQPVEIQPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDHTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=B0ZTA3_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPNAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Collimonas sp. OK412 TaxID=1801619 RepID=A0A1I1MPX9_9BURK +---IARQLRQIEIRSGGRLGVAILDTLTGQSH-AYRGDERFPMCSTFKLLAAGLTLKRVD +QGQEQLARRIRYEAAELVPYSPVTEKHVGGGMSIAELCEATLTLSDNTAANLLLHSFGGP +ARLTAYVRSLGDKATRLDRIEPDLNQATPGDPRDTTSPGAMLSTMHQLLIGNALSADSRK +QLTTWLLANKTGDKRLRALLPAGWRVGDKTGSGAYGSTNDIGILFPPDRAPLLVASYLTA +TKASEATRNAALAEVGRLAA--- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001185801F +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPITEKHVNGTMTLAELSAAALQYTDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTM0_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +RLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q6R3N1_ECOLX +--DVQQKLAELEQQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSCDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1Z1VQJ2_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRIEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0001C05CF6 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2U9GMV9_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIHAGLPASWVVGDKTGSGGYGATNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. CCM 8694 TaxID=2609280 RepID=UPI001420A245 +--EAQAELAALEAAAGGRLGVGAIDTGDGRRL-GHRADERFPMCSTFKAIAAAAILAHGK +HVPGWLDQRVYYTKADLVTYSPITEKHLDDGMTVGELCAATIQYSDNAAANLLMAMIGGP +GGVTGFARSMGDTVFRLDRWETELNTAIPGDPRDTATPAAMAALLRRVALDDGLPAAQRD +QLQNWMRGNTTGDTRIRAAVPASWAVADKTGTGAYGSSNDIGIVFPPKGAPVVLALYYTQ +ADQQAKADSEILAQATRIVMAAf +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013D370D8 +--AVQQKLAALEKSSAGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=Q934I2_BURPE +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRRESELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia mallei TaxID=13373 RepID=UPI000E6CAD3D +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASAPRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KT65_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRANERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTT7_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAERHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQD7_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPSLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDILASAAKIV---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A1W6AKZ1_PSEAI +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRXVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia singularis TaxID=1503053 RepID=A0A238H4H6_9BURK +--DAQRALRELEASFDGRIGVAALDTATNAKI-AYRADERFAFCSTFKMMLSAAVLARSA +AEPDLLPRRIAYAKRDLVEYSPITGKHAGAGMTTAELCAAALQYSDNTAANLLISLLGGT +QAVTAYARSIGDAEFRLDRRETALNTAIPGDLRDTTTPSAMAASLRRLLLGDALGQAQRE +QLNAWMLGNTTGNERIRAGVPPAWRVADKTGTGDYGTANDIGVLYPPGRVPIVLAIYTTG +RAQQARARNDVIASAARIVARAf +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C294F2D +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGXYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A1B2MYQ2_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAATVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0S1Z227_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFAQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q6TGK7_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVIAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ33_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIATD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTF3_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDEMFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZX0_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQHSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0005370826 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATWIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A1KQS3_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPSLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDILASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Methyloligella halotolerans TaxID=1177755 RepID=A0A1E2RWN7_9RHIZ +-dELAKRFAELESSTDGRLGVAVFDSGSAKRS-SYRGDERFPMCSTFKYLAAGAVLKRVD +EGKASLDEKIPITKADMLEYAPVTEKHIGEEMSLEALCEAIVTWSDNPAANLVLKRLGGP +EAVTEFARSLGDEVTRLDRYELALNDVPPGDTRDTTSPRAMANNLDRLVRTDALSDASRR +QLIAWLVDNHTGDNRIRAGLPKDWKVGDKTGTGPRGSTNDVGVAWPPDGKPVFIAVYLTD +TEMPIAKREAVLASVARTVAE-- +>[subseq from] Beta-lactamase (Fragment) n=36 Tax=Bacteria TaxID=2 RepID=A0A0F6T6C9_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase CTX-M-1 n=16 Tax=Enterobacterales TaxID=91347 RepID=BLC1_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas citronellolis TaxID=53408 RepID=A0A127MX92_9PSED +--STLERLKRLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACILARVD +RGEEQLARRIVYGQADLVEYSPASERHVGQPMSVAELCEAAITLSDNGAANLLLASLGGP +TGLTDWLRSTGDDVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDILQPASRD +QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG +SPAPAEKRDALLAEVGRLA---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5B7LK14_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKTVTD-- +>[subseq from] Beta-lactamase n=14 Tax=Gammaproteobacteria TaxID=1236 RepID=Q842A4_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. T529 TaxID=2491343 RepID=A0A561C1H7_9BURK +---AQAQLAALERSVGGRLGVVAFDTATGARV-QHRATERFPMCSTFKMMASAAILDRSS +REPGLLERRVSYARSDILPNSPVTEKHLGEGMTVSALCAATIQYSDNAAANLLMKMLGGP +SAVTAFARSIGDPVFRLDRWETELNSAIPGDPRDTTSPEAMAASLQRLVLGDGLGAAQRS +QLEAWLLGNTTGATRIRAGVPADWKVGDKTGAGSYGTVNDIAVLWPPAGAPLVMAVYLTF +PAQDAPGRNDVIASAARIAVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=E5Q8Z8_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A173GH44_ECOLX +--DVQQKLAELERQSGGRLGVALINTADTSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1S6KJQ6_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQVGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia pseudomallei TaxID=28450 RepID=H9CTS7_BURPE +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFYSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Bradyrhizobium TaxID=2631580 RepID=UPI0009F9D49D +-qRLQQEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRID +RGESSLDQQIRFEAKDILANSPVTKEHVASGMTLAELCEAAITRSDNTAGNMILREIGGP +AGLTGFFRTIGDNVSRLDRWELALNEAVSGDPRDTTSPVAMLKDLQRVVLGDVLSAASRQ +KLIDWMVANKTGDARLRAGVPRDWRVADKTGTGERGTYNDIGVFWPPGRKPIVVTAYLTG +ASAPIEKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium lablabi TaxID=722472 RepID=A0A0R3M8N7_9BRAD +-qRLIDEIKRLESESGGRLGVCVLDTATDTRH-VHRGDERFPMCSTFKALAAAAILARVD +AGKEQLTRRITYDASALVTYSPVTEKHVGDGMTLAEICEAAVTLSDNTAGNLLLAALSGP +PGLTAFARSLGDQVTRLDRNEPSLNEALPDDPRDTTTPSAMASSLQALVVGTALSAPSRE +QLTAWLVANKTGDTRLRAGLPKDWRVGDKTGTGARGTNNDVAVIWPPGKAPIVITGYLTG +ATVPAAQQNAIWASVARAVS--- +>[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. CCM 8693 TaxID=2609000 RepID=UPI0014202A1A +--EAQARLAALEVAYGGRLGVGALDTGDGRRL-GHRADERFPMCSTFKAIAAAAILAHGK +NVPGWLEQRVRYTKADLVTYSPITEKHLDDGMTVGELCAATIAYSDNAAANLLMAKIGGP +GGVTGFARSVGDTVFRLDRWETELNTAIPGDPRDTSTPAAMAALLRRVALDDGLPPAQRD +QLQNWMRGNTTGDTRIRAGVPAGWAVADKTGTGAYGSSNDIGIVFPPRGAPVVLALYYTQ +ADPQAKANSEILAAATRIVMGAf +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A3RLQ6_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=F8UXB4_PROMI +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0S1Z1Z9_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTTFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2Z5WNL3_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGSYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ42_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNAAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=UPI000F814F13 +----ATSFAALEHAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLAHSV +DRPGLLQQRVTYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QFVAWLRGNKVGDKRIRAGVPAGSQVGDKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ +ARADAKPKDDVIAAAARIAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A140CVN0_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +TQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q5MAG0_KLEPN +--AVQQKLAALEKSSGRRLGVPLIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KT79_9BACT +---VQRKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. (strain M1) TaxID=95619 RepID=W5IZ45_PSEUO +--STLERLQQLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACILARVD +RGEEQLARRIVYSQADLVEYSPVSERHVGQPMSVAELCEAAITLSDNGAANLLLASLGGP +AGLTDWLRSTGDDVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLADVLQPASRD +RLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG +SPVPAEKRDALLAEVGRLA---- +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas caseinilytica TaxID=438744 RepID=UPI0007E5B626 +---LEAELASLEQRLDGRLGVTVTDTGSGRHW-GHREDERFPMASTFKVLACAALLDRVD +AGQEELQRRVIYEKDDLVTYSPVTQEHVGEPMTLDSLCEAAMGYSDNSAANMVLKAIGGP +SAVTDFARSLGDDMTRLDRWETKLNEATPGDPRDTTTPAAMAADLQVLFLGDRLSKESRE +RLTDWFLGNRTGDARLRAGLPDDWRIGDRTGSGEHGSTNNVAVAWPSDGEPVIISAYLTE +FEGDMDQRNAAIAEVGKLVTR-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. UFLA 03-321 TaxID=1783512 RepID=A0A1R1QKS8_9BRAD +-qRLQQEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRID +RGESSLDQQIRFEAKDILANSPVTKEHVASGMTLAELCEAAITRSDNTAGNMILREIGGP +AGLTGFFRTIGDNVSRLDRWELALNEAVSGDPRDTTSPVAMLKDLQRVVLGDVLSAASRQ +KLIDWMVANKTGDARLRAGVPRDWRVADKTGTGERGTYNDIGVFWPPGRKPIVVTAYLTG +ASAPIEKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Andreprevotia lacus DSM 23236 TaxID=1121001 RepID=A0A1W1XZV0_9NEIS +--KAAAALAALEQQAGGRLGVYAWDTGSGAIV-NHRADQRFPFCSTFKLMLAGAILARSA +QQPALLTKRIHYRRAQLISHSPQTGQHLDDGMTVAELCAATLQYSDNAAANLLLAQLGGP +AALTAFARSIGDRSFRLDRTEPTLNTAVPGDVRDTTTPAAMARSLHALTLGNALPAAQRQ +QLQDWLRGNTTGDKRIRAGVPAGWAVGDKTGSGAYGTTNDIAVLWPASSAPIVLAIYYTQ +DQPKADWRDAVLAQATRAVLQ-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZZ5_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDCAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6C8RAC7_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASXAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum aquaticum TaxID=568783 RepID=A0A225SVK4_9BURK +--TLTAPLSRLEADIGGRLGVSLVDTAGGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD +QGREQLERRIVYRQQDLVPYSPTTGKHTGGELSVAQLCEAAVTLSDNTAANLMLASMDGP +AGLTRYIRTLGDELTRLDRNEPTLNEATPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ +QLTQWLVANQTGDKRVRAGLPKNWKVGDKTGTGRLGTANDVGVVWTDKGAPLLFAVYLTE +NAATDARRDAVHAEVGRLI---- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DAC7B93 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLERTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas eurihalina TaxID=42566 RepID=A0A5D9D8P0_HALER +---LEAELASLEQRLDGRLGVAVTDTGSGRHW-GHREDERFPMTSTFKVLACAALLDRVD +AGQEELQRRVIYEQDDLVTYSPVTQEHVGEPMTLDSLCEAAMGYSDNSAANMVLKAIGGP +SAVTDFARSLGDDMTRLDRWETKLNEATPGDPRDTTTPAAMAADLQALFLGDRLSEESRE +RLTDWFLGNRTGDARLRAGLPDDWRIGDRTGSGEHGSTNNVAVAWPSDGEPVIISAYLTE +FEGDMDQRNAAIAEVGKLV---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=E2ITW2_SHISO +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAA------- +>[subseq from] Beta-lactamase n=1 Tax=Bordetella flabilis TaxID=463014 RepID=A0A193GEX3_9BORD +--ALHAAFGSLEKSYASRLGVCAIDTANGREI-RHRAEERFPFCSTFKAMAAAAVLARAS +ADPGLLARRIPYTRADLVTYSPITEKHAGAGMTVAELCAATVQYSDNTAGNLLIKLLGGP +PALTAFMRGVGNRSFRLDRWETDLNTAIPGDPRDTATPSDMAHSLNKLVLGGALPAAGRA +QLKEWLVGNTTGDRRIRAGVPDGWQVGDKTGTGSYGTANDIAVLWPPARPPIVLAVYSTQ +PSKTGKPSDALIAEATRVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. Root655 TaxID=1736578 RepID=A0A0Q8FY08_9CAUL +----SRSIIALEARSGGRLGVAALDTQTGATF-AHRGDQRFAMCSTFKALVAGLVLARVD +QGKERLDRRLRYGKQALVAHSPATERHVGDGMTIGALCAATVTLSDNAAANLLLDGFGGP +PALTAFLRGLGDPATRLDRREPELNEARPGDPRDTTTPTAMLGSLRALTLGAALSPASRA +QLVAWLVANQTGGARLRAGLPTGWRVGDKTGSDGEHTTNDIAVIWPPGRAPILITAYLTQ +AKVDSAGRDAVIAEVARIVV--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1S7BFZ7_ECOLX +--XVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGXYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] CTX-M-9 extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0001D34111 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCGTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2R3SK13_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVIWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=Q8VN25_9ENTR +-nSVQQQLEALEKSSGGRLGVALINTAGNSHI-LYRADERFAKCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDVLAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas indica TaxID=137658 RepID=A0A1G9HRK0_9PSED +-eAFERRLARIEDDIGGRLGVALLDLGTGLRA-GWRQDERFPMCSTFKFLAAAAILARQD +QGLDSLERRVKFAAADLVEYSPATGPRADGEMTLAELCEAAVTLSDNTAGNLMLNSLGGP +EGLTAFARSLGDDITRLDRYETALNEALPGDPRDTTTPAAMLADMRELLLGTALSPASRE +RLLGWLVANKTGDARLRAGLPKDWRVGDKTGSGDRGTANDIAILWPPRREPMLVTVYLTG +SDADMNRRNAAIAEVGRLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. CF079 TaxID=1882774 RepID=A0A1G7CTL4_9BURK +--NLSKQLADIEKASGGRLGVGVLDTANGRRA-GHREDERFPLNSTFKFLAAALVLARVD +RRKEQLERRVVIRPGDLVTYSPVTEKHVGAGMTVAELCEATMTLSDNTAGNLLLASFGGA +PGLTAFMRSIGDTNTRLDRTEPALNEGRPGDPRDTTTPAAMTRSMQKILLGDVLSPASRA +QLLQWLDANKTGDERIRAGVPADWKVGDKTGSGEN-GANDVAILRPPGRAPILLSVYLTQ +TRAPAAVRNRALASVAAVAAE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTM4_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETLRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. C9 TaxID=142585 RepID=A0A2A6NN08_9BRAD +-kRLQEEFARIELATSGRLGVAALDMETGLRA-SQRGDERFPMCSTFKALASAAVLHRVD +RGESSLDQRVQVEAKDILAYAPVAKQHVGSSMTLSELCEAAITLSDNTAANLLLREIGGP +AGFTSFFRTIGDNVSRLDRWEVALNEAVPGDLRDTTSPVAMLKSLQRVVIGDVLQAASRQ +KLMGWMVANKTGDTRLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPTDKCDEVIANVARAVAN-- +>[subseq from] Beta-lactamase n=2 Tax=Halomonas caseinilytica TaxID=438744 RepID=A0A1M6VA64_9GAMM +---LEAELASLEQRLDGRLGVTVTDTGSGRHW-GHREDERFPMASTFKVLACAALLDRVD +AGQEELQRRVIYEKDDLVTYSPVTQEHVGEPMTLDSLCEAAMGYSDNSAANMVLKAIGGP +SAVTDFARSLGDDMTRLDRWETKLNEATPGDPRDTTTPAAMAADLQVLFLGDRLSKESRE +RLTDWFLGNRTGDARLRAGLPDDWRIGDRTGSGEHGSTNNVAVAWPSDGEPVIISAYLTE +FEGDMDQRNAAIAEVGKLVTR-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A2Z6TLY2_BURVI +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVAWMRGNQVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ +ARADAKAKENGMAGAARIAVGTf +>[subseq from] Beta-lactamase n=1 Tax=Bosea sp. Tri-44 TaxID=1972137 RepID=A0A4Q1VT64_9BRAD +-eEVREALFALDRRHGGRLGVAILDSGSGRVI-AHRGQERFAMCSTFKFVAAAFVLARVD +RGEESLDRRVSYTKTDLVTYSPVTEKHVDTGLTVAELCDAAVTLSDNAAGNLLLDSFGGP +KGLTSYMRSLGDDSSRLDRRELELNEATPGDPRDTTTPVAMAQILRQTVLGAALSPASRH +QLTAWLVANKTGDKRLRAGVPKGWRVGDRTGTGSNNATNDIGVIWPPGRAPLIVTAYYAE +SRGSLPEREAVLAEVGRLAT--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B4E8362 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCGTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTU2_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTASPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Providencia rettgeri TaxID=587 RepID=C7FE03_PRORE +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKAMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI00076319CD +--ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWKVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARKDVLAGAAKIVASGy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L060_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLVSHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobiales bacterium GAS191 TaxID=1882830 RepID=A0A1H5JPA0_9RHIZ +--KLAEEFARLEGKSGGRLGVAMLDTGTGMRA-GHRQEERFPMCSTFKLLAAAAVLDRVD +AGKESLDRRIRFEAADILSNAPITKDHIGGDMTIAELCAAAITLSDNTAANLLLASFGGP +AGLTAYVRKLGDSTTRLDRNEPSLNTAVPGDPRDTTTPSAMLSTLQALTLGQALSVSSRE +RLIGWLVANKTGDARLRAGLPKTWRVGDKTGAGAHGTTNDVAIAWPPGRAPLLICTYLTG +SSANDDGRNAILAAVALAIAAGf +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI0013755FF0 +--ALQRGIQQLEKNAGGRVGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARKDVLAGAAKIVASGy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1S7BHI3_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTSSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YE46_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAA------- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI00141E3A4F +--DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAA +GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAHARSIGDATFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR +PDKDAKYDNAAIAAVARIVTATf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A165TI35_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTSAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Bosea sp. CF476 TaxID=2135474 RepID=A0A318X3S3_9BRAD +-eEVREALFALDRKHGGRLGVAILDSGSGRVV-AHRGEERFAMCSTFKFAAAAYVLARVD +RGEEELERRVSYSKADLITYSPVTEKHVDRGMTIAELCDAAVTLSDNAAGNLLLDSFGGP +KGLTAYMRALGDEASRLDRRELDLNEATPGDPRDTTTPVAMAGVLRQTVLGGALSPASRQ +QLTAWLVANKTGDKRLRAGVPKGWRIGDKTGTGNNNATNDIGVIWPPGRAPLVVTAYYAE +SRASFPEREAVLAEVGRLA---- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTD7_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRLDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=G9FYZ9_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIQGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q4JNX3_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTETTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AKY5_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASXAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTF0_9BACT +--DVQQKLAELERQSGGRLGMALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000D782462 +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA +QLVAWMRGNQVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ +ARADAKAKENGMAGAARIAVGTf +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F749CFB +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALWPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=UPI000993FFC5 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTISLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000B7ECB55 +--ALQRDIQQLEKNAGGRLGVAVTDTADGAVF-TYRGEARFPLCSTSKVFAVAAILKKSE +SANGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARRDVLAGAAKIVASGy +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas caseinilytica TaxID=438744 RepID=UPI0008492A6C +---LEAELASLEQRLDGRLGVAVTDTGSGRHW-GHREDERFPMTSTFKVLACAALLDRVD +AGQEGLQRRVIYEQDDLVTYSPVTQEHVGEPMTLDSLCEAAMGYSDNSAANMVLKAIGGP +SAVTDFARSLGDDMTRLDRWETKLNEATPGDPRDTTTPAAMAADLQMLFLGDRLSKESRE +RLTDWFLGNRTGDARLRAGLPDDWRIGDRTGSGEHGSTNNVAVAWPSDGEPVIISAYLTE +FEGDMDQRNAAIAEVGKLVTR-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. STM 3843 TaxID=551947 RepID=H0TZ06_9BRAD +--EIDVTIAEIEAKSGGRLGVALLDTASGELT-GHRLDERFPMCSTFKVLAVAAVLARVD +AGQEQLGRRIPITQADLLSYAPVTKTHLDSGMTVAELCEAAITLSDNTAANLLLASFDGP +PALTRYLQSLGDSVTRVDRIEPDLNEATPGDPRDTTTPAAMAKTVAKLVTGSALSATSRE +MLIGWMIDCKTGAARLRAGLPSGWRIGDKTGSGSHGSANDVAVIWPQNRAPLIVTSYLTE +TDLSDEKRNAVHAEIGRIVAR-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ44_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +AGVTALARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDILASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000E233E68 +--ALQRGIQQLEKNTGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARKDVLAGAAKIVASGy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTQ2_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRTMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum sp. WT00C TaxID=1892903 RepID=UPI000949C822 +-dALTARLSRLEADIAGRLGVSLLDTASGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD +QGQEQLTRRVVYQKQDLVPYSPTTGKHTGGALSMAQLCEAAMTLSDNTAANLMLASMGGP +AGLTRFVRTLGDELTRLDRNEPTLNEAVPDDPRDTTTPAAMTADLRQLVLGNALTPASRQ +QLTQWLIANQTGDKRVRAGLPASWKVGDKTGTGRLGTANDIGVVWTTQGAPLLFAVYLTE +NAATDAGRDAVHAEVGRLI---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Morganella morganii TaxID=582 RepID=I7ABV1_MORMO +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIV---- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A345T8M3_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASITAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Massilia sp. SOD TaxID=2495579 RepID=A0A430HLS1_9BURK +--EAQARLAALETAAGGRLGVDAIDTGDGRRL-GHRADQRFPMCSTFKAIAAAAILAHGK +NVPGWLDQRVRYGKADLVSYSPLTEKHVDAGMTIGELCAATIQYSDNAAANLLMKLIGGP +DGVTGFARSVGDTVFRLDRWETELNTAIPGDPRDTSTPAAMASLLRRVALDDGLPAAQRD +QLQNWMRGNTTGDTRIRAGVPAGWAVADKTGTGAYGSSNDIGIVFPPQGAPVVLALYYTQ +ADPQAKANSEILAAATKVVMAAf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZC0_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVIWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=A0A2U1DHE1_PANAN +--ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARKDVLAGAAKIVASGy +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000D7539B0 +--ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARKDVLAGAAKIVASGy +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI00061C5136 +--ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPAGWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAVARKDVLAGAAKIVASGy +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2PT38_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEQTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=I1V556_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +TSVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase class A n=1 Tax=Abditibacterium utsteinense TaxID=1960156 RepID=A0A2S8SXL9_9BACT +----KARLAKLEREFGGRLGVFAVNSANGERL-IYRADERFPVCSTFKVLLASAILKRSV +QVPGLLHQRIKYQPSQLVSYSPITEKHVAQGMTVAQLCAAALQYSDNTASNLLMKILGGP +RAVTAFARAIGDSEFRLDRWETALNTAIPGDLRDTSTPQAMGRSVQRLVAGNVLAPQHRA +QLQRWMQGNTTGDTRIKAGIPANWKIGDKTGTGDYGTANDIAVVWPPHHEPVILTIYTTQ +HQKEAKARNDVIASAAKVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. CCBAU 051011 TaxID=858422 RepID=UPI001374285C +-qRLIDEIKRLESESGGRLGVCVLDTATGARH-VHRGDERFPMCSTFKALAAAAILARVD +AGKEQLTRRITFEASALVTYSPVTEKHVGGDMTLAEICEAAVTLSDNTAGNLLLSALGGP +PGLTAFARSLGDQITRLDRDEPSLNEALPDDPRDTTTPNAMASNLQALVVGTALSAPSRE +QLTAWLVANKTGDTRLRAGLPKDWRVGDKTGTGARGTNNDVAVIWPPGKAPIVITGYLTG +ATVPAAQQNAIWASVARAVS--- +>[subseq from] Class A beta-lactamase n=1 Tax=Ewingella americana TaxID=41202 RepID=A0A502G9Q0_9GAMM +--AIQQKLAALEKNSGGRLGVVLINTADNTRI-EYRGDERFPMCSTSKVMAASAILKQSE +TEKELLNQRVEIKKSDLVNYNPIAEKHLDTGMTLAELSAAALQYSDNTAMNKLIAQLGGP +VGVTKFARSIGDTTFRLDRTEPTLNTAIPGDKRDTTSPLAMATSLHNLTLGKALGEPQRA +QLVEWLKGNTTGAESIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPENHPPLVVVTYFTQ +PHQNAKARKDVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000CF56AB1 +--ALQRGIQQLEKNAGGRLGVAVTDTADGAVF-TYRGDARFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQNLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARKDVLAGAAKIVASGy +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=C3TTN7_BURPE +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFYSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP +QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas knackmussii (strain DSM 6978 / LMG 23759 / B13) TaxID=1301098 RepID=A0A024HKE1_PSEKB +-kALEAQLAKLERGSGGRLGVAVLDTGSGKRF-GHRADERFPMCSTFKALLAAAVLARVD +AGKEDLARRIIYGREALVDYSPVAEKHVGEPLSVAELCKAAVTLSDNGAANLLLESLGGP +AGLTAWLRTTGDTVTRLDRNEPDLNEGTPGDPRDTTTPTAMLETLQHLLLGNVLKASSRD +QLKAWLLANQTGDARLRAGVPMDWKVGDKTGTGPTGTSNDIAILYPPGRAPLLVTAYLTR +ATVSPEQRDKVLAEVGRLAA--- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0006177D13 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGL +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPATMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. DHOD12 TaxID=2571746 RepID=A0A4V1EII3_9BURK +--TVQAELAKLEASSGGRLGLAAIDTGSGARL-LHRADERFAFCSTFKVIAASAILKRSE +NEPGLLERRVIYSTQDLVTYSPITKPNVASGMTVAELCAAAIDYSDNTAGNLLMKILGGP +QAVTAFARSIGNETFRLDRWETELNTAIPGDLRDTSTPASMAHSLQQLALGDALAPRQRE +QLQAWLRANTTGGKRIRAGVPADWQVGDKTGTGDYGTTNDIGVVWRPSGAPLVIAIYFTQ +PRQDASPRDDVLAAAARIVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1Z1VNJ2_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDRTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobiales bacterium GAS113 TaxID=1884352 RepID=A0A1H1K181_9RHIZ +--KLAEEFARLEGKSGGRLGVAVLDTGTGMRA-GHREEERFPMCSTFKLLAAAAVLDRVD +AGKESLDRRIRFEAADILSNAPITKDHIGGDMTIAELCAAAITLSDNTAANLLLASFGGP +GGLTAYVRKLGDSTTRLDRNEPSLNTAVPGDPRDTTTPSAMLSTLQALTLGQALSVSSRE +RLIGWLVANKTGDARLRAGLPKTWRVGDKTGAGAHGTTNDVAIAWPPGRTPLLICTYLTG +SSANDDGRNAILAAVALAVAAGf +>[subseq from] Beta-lactamase n=1 Tax=Massilia sp. TaxID=1882437 RepID=A0A350CRQ7_9BURK +--TVTADFAALEAGLDGELGVAAIDTATGRTI-GHRQDQRFPMCSTFKVVLAAAVLARAA +REPGLLDRRLPLPKSVFVDWSPITGKHVDGDMSVAQLCAATLQYSDNTAGNVLLREVGGP +AGLTRHARALGDEHFRLDRWETELNTATPGDERDTTTPLAMARTLRKLLLLDGLPPAGRN +TLRDWMLGNTTGAARIRAGVPAGWQVADKTGTGSYGSASDIAVVYPPGKAPIVLAIYTRQ +SEKNAKARNDIIAEAAQIAVS-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI001370E264 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKFDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Class A extended-spectrum beta-lactamase CTX-M-143 n=1 Tax=Escherichia coli TaxID=562 RepID=A0A650A8E7_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLSTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000F5405EC +--DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAA +GDARLLSSVIRYTRRDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR +PDKDAKYDNATLAAVARIVTATf +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=C1J898_BURVI +----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV +EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP +AAVTAYARSIGDDTFRLDRWETALNTALPGDLRDTTTPAAMAASIRVLTLGDALPAAQRT +QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ +ARADAKAKENVIAAAARIAVATf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0S1Z261_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLTELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Extended spectrum beta-lactamase CTX-M n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTW2_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFATCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Duganella sacchari TaxID=551987 RepID=A0A1M7NTN5_9BURK +----TAQLALLEKESGGLLGVAALNTGDGRQL-LHRADERFPVCSTFKMMLSAAVLARDP +---ALLKKRIPYEKSDLVPHAPITSKHVGEGMTVAELCEATLQYSDNPAANLLMKQLGGP +AAVTAYARSIGDSEFRLERWETELNTAIPGDPRDTTTPEAMARSLQKLVLGDALPPTQRK +QLKDWMLGNTTGATRIRAGVPAGWPVADKTGAGDYGTVNDIAVIWPPGKAPIVLAVYLTQ +PGKDDKSHPEIHGEVAKIVIEAf +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. Sh1 TaxID=2607285 RepID=A0A5A9EWB3_9PROT +--ALAGKMTELEARSGGRLGVAVLDTANGKLH-GWRGDERFPMCSTFKFLLAAAVLKTVD +QGKDRLDRRIPVTKADLVPYAPFAETRLNGTPTVAELCEAAMTLSDNVAANLLLPGIGNP +AGLTAFMRGIGDRTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMERILVGDVLRPDSRR +QLIDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAIVWPEGRAPLLVACYLTQ +TAEGFKQQDSIHAEVARTVA--- +>[subseq from] Beta-lactamase n=1 Tax=Phyllobacterium sp. OV277 TaxID=1882772 RepID=A0A1H0PBH6_9RHIZ +--SLEAAFKDLEKATGTRLGVSAHDTGSGKRI-DYREKELFAMCSTFKFFAAAAILARVD +QKKEQLDRIVTYKKSDLVDYSPVTEKHVGEGMSLAAICEAAITYSDNSAGNLMLDALGGS +KGLTEYARSLGDTITRLDRRETELNEATPGDPRDTTTPAAMRENLEKTVLGTALSEQSRK +QLADWLIGNKVGDKRLRAGLPKDWKVGDKTGTSDSGMANDVAVIWPPDRKPIVLTVYLYD +PKGTADSRNAIHQKVASLIAEH- +>[subseq from] Beta-lactamase n=1 Tax=Buttiauxella brennerae ATCC 51605 TaxID=1354251 RepID=A0A1B7IRG5_9ENTR +---IGKKLAELEKSTGGRLGVVLINTADNSQI-VYRGDERFPMCSTSKVMAASAILKQSE +TQTGLLNQRVEIKKSDLVNYNPITEKHLDGGMTIAELTDATLRYSDNTAMNKLIAQLGGP +DKVTQFARSIGDKTFRLDRTEPTLNTAIPGDERDTTTPAAMAKTLQNLTLDNALAEPQRK +QLVEWMKKNTTGGASIRAGLPTTWTVADKTGSGSYGTTNDIAVIWPENQPPLVLVTYFTQ +PQKEAKSRNDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ56_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKRVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDILASAAKIVTD-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F82FDF5 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQCSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia kunmingensis TaxID=630975 RepID=UPI001150273A +-----DHLAALEGRFDARLGVYALDTGSGREL-AHRADERFAMCSTFKALAAAAVLDATP +--PEYLDHRVHYQQADLAAYSPVAERHVADGMTIRELCDAAVRFSDNTAGNLLLEELGGP +GGITAFARSLGDDVTRLDRTEPELNTAIPGDERDTTSPRAIAGCVDALVLGDRLDPADRA +LLTEWLVGNTTGAARIRAGVPQGWRVGDKTGTGDYATANDVGVVWPPDRAPIVLAILTSR +ATEDADVDEALLAEATRVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum rubrisubalbicans TaxID=80842 RepID=UPI00030ED6FE +--AISARLARLEAGIGGRLGVSLVDTAGARQW-GYRADERFPMCSTFKWLAAAALLRRVD +EGREQLTRRIVYHQRDLIPYSPTTGKHVGGTLSLAQLCEAAVTLSDNTAANLMLASMGGP +AGMTAFVRTLGDALTRLDRNEPALNQAVPDDPRDTTTPAAMTADLQRLVLGDALTPASRA +QLTQWLLANQTGDKRVRAGLPAGWKVGDKTGTGRLGTANDVGVVWTPQGKPLLFAVYLTE +NAADDARRDALHAEVGRLIAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia kunmingensis TaxID=630975 RepID=A0A543DNQ8_9PSEU +-----DHLAALEGRFDARLGVYALDTGSGREL-AHRADERFAMCSTFKALAAAAVLDATP +--PEYLDHRVHYQQADLAAYSPVAERHVADGMTIRELCDAAVRFSDNTAGNLLLEELGGP +GGITAFARSLGDDVTRLDRTEPELNTAIPGDERDTTSPRAIAGCVDALVLGDRLDPADRA +LLTEWLVGNTTGAARIRAGVPQGWRVGDKTGTGDYATANDVGVVWPPDRAPIVLAILTSR +ATEDADVDEALLAEATRVVVA-- +>[subseq from] Beta-lactamase n=2 Tax=Halomonas elongata TaxID=2746 RepID=A0A1B8P6S8_HALEL +---LEAELASLEQRLDARLGVAVTDTGSGRHW-GHREDERFPMTSTFKVLACAALLDRVD +AGQEELQRRVIYEQDDLVTYSPVTKEHVGEPMTLDSLCEAAMGYSDNSAANMVLKAIGGP +SAVTDFARSLGDDMTRLDRWETKLNEAIPGDPRDTTTPAAMAADLQALFLGDRLSEESRE +RLTDWFLGNRTGDARLRAGLPDDWRIGDRTGSGAHGSTNNVAVAWPADGEPVIISAYLTE +FEGDMDQRNAAIAEVGKLVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=E0WC49_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGTGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. TSO5 TaxID=716760 RepID=A0A2U1YM52_9PROT +-dALAAKMTELEARSGGRLGVAVLDSGNGKLH-GWRGDERFPMCSTFKFLLAAAVLKTVD +QGKDRLDRRIPVTKADLVPYAPFSETRLDGTPTVAELCEAALTLSDNVAANLLLPGIGNP +AGLTAFMRGIGDKTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMERILVGDVLRPDSRR +QLIDWMVANKTGDKRLRAGLPAGWRVGDKTGTGSYGSANDIAIVWPEGRAPLLVACYLTQ +TAEGFKQQDSIHAEVARAVA--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KT53_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRVDERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTF6_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRLDVLASAAKIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Aquamicrobium sp. LC103 TaxID=1120658 RepID=A0A4U6C258_9RHIZ +--ELADRLRDIETAAGGRLGVAILDTGNGVRV-EHRAHERFAMCSTFKFLAAACVLARVD +RGEEQLDRRVTFAKDDLVTWSPVTEKHAGDGMTMTQLCHAAVTVSDNTAGNLLLTSFGGP +AGLTAFARSLGDELTRLDRIEPGLNEATKGDPRDTTTPAAMLGNLDRTVLGDALSPASRD +RLGAWLRANTTGDKRLKAGLPAGWTIGDKTGTGGNGATNDVGVIWPPEHAPIIVSAYLAE +TTIAPEKREAALREVGRIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=A0A2A7SFF6_BURGA +--DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAA +GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR +PGKDAKYDNAILAAVARIVTATf +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A0S1Z249_ENTCL +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARLLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L057_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTSNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Chitinimonas sp. R3-44 TaxID=2594795 RepID=A0A516SCU7_9MICO +--TAQAQLAQLELAFKGRIGFFAIDTGNGSSL-GYRADERFPMCSTFKMMLAAAILARST +QTDGLLKQRIQYGQHDLLPHSPITEQHLKDGMPVADLCAATVQYSDNGAANLLMKILGGP +AALTAFAQSIGDHTFRLDRWETELNTAIPGDGRDTTTPAAMGRSLQGLALGNALPPPQRE +QLQTWLLGNTTGATRIQAGVPAGWRVGDKTGTGSYGTANDIAVLWPAHRAPVVVTVFTTQ +KEQHAKARNDVIASAARIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=C0LRU8_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDETFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia TaxID=32008 RepID=UPI00075D3F96 +--DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAT +GDARLLSSVIRYTRRDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR +PDKDAKYDNATLAAVARIVTATf +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia gladioli (strain BSR3) TaxID=999541 RepID=F2LLP9_BURGS +--DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAA +GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR +PDKDAKYDNATLAAVARIVTATf +>[subseq from] class A beta-lactamase n=1 Tax=Aureimonas sp. AU12 TaxID=1638161 RepID=UPI0007808677 +-------TERIETRLGARLGVFALDTGSGRRW-EHRANERFPMCSTFKVVACGAVLARVD +AGAENLDRRIRFETSDLVPYSPETERHVGGDMTLRAICEAAMTQSDNTAANLILASLGGP +AAVTAYARSIGDQETRLDRIETALNEATPGDPRDTTTPAAMAGNLRALAFGDALSPTSRV +VLTGWMVANRTGGAKLRAGLPDGWRVGDKTGGGDHGTMNDVAVIWPAGGEPVIIAVYMTE +TAASFDDRNAGIAEIGRGL---- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. PIC25 TaxID=1958773 RepID=A0A2A2ECJ8_9PSED +-qDIERRLAGIEEGVGGRLGVALLDLGTGLRA-GWRQDERFPMCSTFKFLAAAAILARQD +QGLDSLGRRVKFTTANLVEYSPATGPRADGEMTLAELCEAAVTLSDNTAGNLMLNSLGGP +EGLTAFARSLGDEVTRLDRYETALNEALPGDPRDTTTPAAMLDDMRKLLLGSALSPASRE +RLLGWLVANKTGAARLRAGLPKDWRVGDKTGSGDRGTANDIAILWPPGREPVLVTVYLTG +SDTDMNRRNAAIAEVGRLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A097KV69_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSVAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum seropedicae TaxID=964 RepID=A0A4R8NC96_HERSE +--ALTATLSRLEADIGGRLGVSLVDTAGGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD +EGKEQLARRIVYRQQDLVPYSPTTGKHTGGDLSLAQLCEAAITLSDNTAANLMLESMDGP +AGMTRFVRSLGDDLTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ +QLAQWLVANQTGDKRVRAGLPKGWKVGDKTGTGRLGTANDVGVVWTEKGAALLFAVYLTE +NAATDARRDAVHAEVGRLI---- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. RIT 412 TaxID=2202161 RepID=A0A329IUJ5_9PSED +-tDLERQLAALERRHGGRLGVAMLDTGNQRLI-AHRADERFAMCSTFKALAAAYVLARVD +RGEEDLSRRVVYGPEQLVPYSPVTQKHTGEGLSVGSICEAAVTLSDNTAANLLLDSFGGP +QGLTDWLRRAGDPVTRLDRREPTLNENRPGDVRDTTTPLAMLRTLQTLALGEALSGASRD +QLIAWLVSNTTGDQKLRAGLPAGWRVGDKTGSGSNNASNDIAIVWPPNRPPLIVTVYYSG +STADAGQVNALMAEIGNYAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=UPI00047FB2A9 +-qRLSDEIKRLESESGGRLGVCVLDTATNTRH-DHRGDERFPMCSTFKMLAAAAILARVD +AGHEQLTRRITFDASALVVYSPITEKRVGGDMTLAEICEAAVTLSDNTAGNLLLASIGGP +PGLTAFARSLGDQVTRLDRDEPSLNEALPDDPRDTTTPNAMASNLQALVLGTALSAASRE +QLTAWLIANKTGDTRLRAGLAKDWRVGDKTGTGARGTNNDVAVTWPPGKAPIVITAYLTG +STVSAAQQNAILASVARAVS--- +>[subseq from] Beta-lactamase n=1 Tax=Bosea sp. Tri-39 TaxID=1867714 RepID=A0A4Q1TXN4_9BRAD +-eEVREALFALDRKHGGRLGVAILDSGTGRVI-AHRGEERFAMCSTFKFVAAAFVLARVD +RGEEELERRVSYSKADLVTYSPVTEKHVEKGLTVAEICEAAVTLSDNTAGNLLLDSFGGP +KGLTGYMRSLGDEASRLDRRELELNEATPGDPRDTTTPVAMASVLRQTVLGGALSPASRQ +QLTAWLVANKTGDKRLRAGTPKGWRIGDKTGTGNNNATNDVGVIWPPGRAPLVVTAYYAE +AQVSFAEREAVLAEVGRLAV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL01_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAXKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum seropedicae (strain SmR1) TaxID=757424 RepID=D8J247_HERSS +--ALTARLSRLEADIGGRLGVSLLDTASGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD +QGQEQLTRRIVYQKQDLVPYSPTTGKHTGGALSMAQLCEAAMTLSDNTAANLMLASMGGP +AGLTRFVRTLGDELTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ +QLTQWLIANQTGAKRVRAGLPASWKVGDKTGTGRLGTANDIGVVWTAQGAPLLFAVYLTE +NAATDAGRDAVHTEVGRLI---- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTG5_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAGLSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. aSej3 TaxID=2605638 RepID=A0A5S4YXG9_9BRAD +---LEEELARIERDSLGRLGVAVLDTETGLET-GLRAGERFPMCSTFKCLASAAVLKRVD +RAELGLEQLIRFEAKDVVQYSPATKDRVAAGMTLAEICEAALTQSDNTAGNLLLRQIGGP +DGLTSFLRSLGDNVSRLDRWEVELNEALPDDPRDTTSPAAMLQNLHRLMVGDALSAASRQ +RLTDWMVANKTGDTRLRAGVPRGWRVADKTGAGDRGTTNDVGVFWPPGRKPVLVAAYLTG +SQGSPEKRNATIAEVGRLVAE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTS9_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGGKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Extended spectrum beta-lactamase CTX-M n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZY0_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFATCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=A9XG17_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTESTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudoduganella danionis TaxID=1890295 RepID=A0A6A8VZ43_9BURK +----TALLARLESESGGRLGVFALNTADGQHV-QHRADERFPFCSTFKMMLAGAVLARGP +---ALLAQRIPYGSADLLPHSPITGKHVGRGMTVAALCAATIQYSDNAAANLLIARLGGV +AAVTAFARSIGDQAFRLDRLETELNTALPGDLRDTTTPAAMAESLNRLVLGNALTTAARK +QLKDWLLGNTTGDTRIRAGVPSGWLVADKTGTGDYGSTNDIGVIWPPGKEPIVLAVYFTQ +PGKDDKARNEVIAEATRIALAAf +>[subseq from] Beta-lactamase n=1 Tax=Bosea lupini TaxID=1036779 RepID=A0A1H7UUZ2_9BRAD +--KLREGLFALDRKHGGRLGVAILDSGNGRIV-AHRGEERFAMCSTFKFVAAACVLARVD +RGEEELERRVSYSKADLVTYSPVTEKHVEKGLTLAEICDAAVTLSDNTAGNLLLDSFGGP +KGLTAYMRSLGDDASRLDRREPDLNEARTGDPRDTTTPVAMAGVLRQTVLGGALSPASRQ +QLTTWLVANKTGDKRLRAGVPKGWRIGDKTGTGNNNATNDIGVIWPPGRAPLVVTAYYAE +ASAAFPEREAVLAEVGRLA---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=V5MYM2_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKSVTN-- +>[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0006806B83 +--AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLACSA +GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGL +QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA +QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM +RNPNAQARDDVIASATRIAARAf +>[subseq from] class A beta-lactamase n=1 Tax=Bosea sp. FBZP-16 TaxID=2065382 RepID=UPI000C31B657 +--KLREGLFALDRKHGGRLGVAILDSGNGRIV-AHRGEERFAMCSTFKFVAAACVLARVD +RGEEELERRVSYSKADLVTYSPVTEKHVKKGLTLAEICDAAVTLSDNTAGNLLLDSFGGP +KGLTAYMRSLGDDASRLDRREPDLNEARTGDPRDTTTPVAMAGVLRQTVLGGALSPASRQ +QLTTWLVANKTGDKRLRAGVPKGWRIGDKTGTGNNNATNDIGVIWPPGRAPLVVTAYYAE +ASAAFPEREAVLAEVGRLA---- +>[subseq from] class A beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=UPI000E6A04F8 +-kRLAGAIAALEKRSGGRLGVAVLDTGTGQSF-GHRADERFAMCSTFKFLLAGAILKQVD +EGRERLDRRIPVSKADMVPYAPFVETRLDGPPTVVELCEATMTLSDNVAANLLLPAVGDP +AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRE +QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLIASYLTE +TADGFKERDATHAGVARAVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. 7(2017) TaxID=1404411 RepID=UPI0014091DA5 +--RLQQEFARIELATSGRLGVAAHDMETGLRA-SQRGDERFPMCSTFKALASAAVLHRVD +RDESSLDQRVQIEAKDILAYAPVTKEHVGSSMTLSELCEAAITLSDNTAANLLLREIGGP +AGLTSFFRTIGDNVSRLDRWEVALNEGVSGDPRDTTSPVAMLKNLQRVAIGDVLQATSRQ +RLIDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMDKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZW1_9BACT +--DAQQKLAELERQSGGRLGVALINTADNSQI-LYRANERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLATWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=A0A2R3SK36_PROMI +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTETTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L041_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTSDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Serratia sp. DD3 TaxID=1410619 RepID=A0A083ZY90_9GAMM +-qQAQQQLAALEKQHMGRLGVFAIDTTSSNTL-QLNAHQRFAFCSTFKVIAVAAILHHSL +SHPGFLDQRIHYQASDLVTYSPITEKHLDSGMTIAELCAAALQYSDNTAGNMLMKQLGGP +AAITAYARSLGDTTFRLDRWETELNSAIPGDERDTTTPAAMAASLQKLTLGTALPEAQRQ +QLVNWMKGNTTGNKRIRAGMPPDAVIADKTGGGDYGTTNDIGVVWLSGRAPWLVVIYFTQ +PNQHATANNEAVAAAARIISQAf +>[subseq from] Beta-lactamase n=3 Tax=Pantoea ananas TaxID=553 RepID=A0A0H3KVV5_PANAA +--ALQRGIQQLEKNAGGRLGVAVTDTTDGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARKDVLAGAAKIVASGy +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. B40 TaxID=95608 RepID=UPI0003492979 +--ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKSNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARKDVLAGAAKIVASGy +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5P8NAU0_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNIAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQA5_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKPDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILITYFTQ +PRPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Duganella sp. BJB480 TaxID=1871181 RepID=A0A3E1S8I8_9BURK +-----ALLAKLEADSGGRLGVAAMNTADGRRL-LHRADERFPFCSTFKMMLAAAVLAK-- +-GPALLKKRVRYSKADMVTYSPVTEKHIGRGMTVAALCEATIQTSDNTAANLLMKQIGGP +AAVTAFARSIGDMEFRLERMETELNTALPGDPRDTTTPASMVESLHKLVLGDGLGAAQRK +QLKDWMLGTTTGDTRIRAGVPAGSQVADKTGTGDYGTTNDIGVIWQPGKAPVALVVYLTQ +PGKDDKARSEIIAEAARIVVEAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A097BQW2_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTAPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ85_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDCGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobiales bacterium GAS188 TaxID=1884351 RepID=A0A1H5FAC5_9RHIZ +--KLAEEFARLEGKSGGRLGVAMLDTGTGMRA-GHRQEERFPMCSTFKLLAAAAVLDRVD +AGKESLDRRIRFEAADILSNAPITKDHIGGDMTIAELCAAAITLSDNTAANLLLASFGGP +AGLTAYVRKLGDSTTRLDRNEPSLNTAVPGDPRDTTTPSAMLSTLQALTLGQALSVSSRE +RLIGWLVANKTGDARLRAGLPKTWRVGDKTGTGALGTTNDVAIAWPPGRAPLLICTYLTG +SSANDDGRNAILAAVALAIAAGf +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. TSA2s TaxID=709810 RepID=A0A4P7Z5E8_9PROT +--ALAGKMTELEARSGGRLGVAVLDTANGKLH-GWRGDERFPMCSTFKFLLAAAVLKTVD +QGKDRLDRRIPVTKADLVPYAPFSETRLNGTPTVAELCEAAMTLSDNVAANLLLPGIGNP +AGLTTFMRGIGDKTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMERILVGDVLRPDSRR +QLIDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAIVWPEGRAPLLVACYLTQ +TAEGFKQQDSIHAEVARAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Skermanella pratensis TaxID=2233999 RepID=UPI0013015891 +--DLAGKLTEVERRLGARFGADILDTESGRRW-AHRAEERFPLCSTFKAIACGAVLAKVD +AGREDLERRIRFEAGDVVTYSPVTQDRVGGDMTLAEICEAAMTRSDNTAGNIILDSLGGP +AGVTEFARSLGDTVTRLDRWETDLNEATPGDPRDTTSPAAMVANLESLVLGDTLSRPSRD +RLTAWLVSNKTGDAKLRAGLPKDWRIGDKTGGGDHGTMNDVAVIWPPGRKPVIVSIYMTE +TKASFDDRNAAIAEIGRAL---- +>[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. FT127W TaxID=2660641 RepID=UPI00136A04F6 +------AFAALEKDLGGRLGVAAINLSNGKQA-GHRAGERFPLCSTFKAVLAAAILQRSA +SDPSLLQRRIHYTEKDLVPHAPITGERIAKGMTVEELCAATVQYSDNPAANLLMKVLGGP +EAVTAFARSVGDTEFRLDRWETELNTAIPGDPRDTTTPQAMMRSLQALVVGDALPAPQRQ +QLKEWLVGNTTGGKMIRAGTPAGWTVGDKTGGGAYGARNDIAVIWPPGKAPIVIAIYTAH +SQEDAKYREDIIAGATRAAI--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q6W8V9_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGSGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A023PZG3_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDLRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Duganella TaxID=2636909 RepID=UPI0012B06126 +-------LARLEKESGGRLGVAALNTADGRQL-AHRADERFPMCSTFKMMAAAAILSRDP +---SLLKKHIQYEKSDLVSHSPVTGKHVAEGMTVAELCEATLQYSDNAAANLLMKQLGGP +AAVTAYARSIGDNEFRLDRWETELNSALPGDARDTTTPLSMARSLQKLVLGDALPAPHRR +LLKDWMIGNTTGATRIRAGVPSGWTVADKTGAGDYGSVNDIAVLWPPGRAPIILAVYLTQ +PGKDDKLRPEIHGEVARVVIEAf +>[subseq from] UPI00144A4C37 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00144A4C37 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCXTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. AMG 501 TaxID=2008894 RepID=UPI000B5AB183 +--ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWAVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARKDVLAGAAKIVASGy +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum huttiense TaxID=863372 RepID=A0A561KWY6_9BURK +--TLTATLSRLEADIGGRLGVSLVDTAGGRHW-GYRADERFPMCSTFKLLAAAAVLRRVD +EGKEQLERRIVYRQQDLVPYSPTTGKHTGGELSLAQLCEAAVTLSDNTAANLMLASMNGP +AGLTHYIRTLGDELTRLDRNEPTLNEATPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ +QLTQWLVANQTGDKRVRAGLPKSWKVGDKTGTGRLGTANDVGVVWTDKGAPLLFAVYLTE +NAATDARRDTVHAEVGRLI---- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q5MAF7_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDGTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Aurantimonas aggregata TaxID=2047720 RepID=UPI0013D83F87 +---FARRLAEIEDGLTARLGVAVLDTETGQRW-TRRGNERFPMCSTFKAVASGAVLARVD +AGEEDLGRRIVFAKSDLVPYSPGTENRVGGDMTLAELCEAAVTLSDNTAANLILASLGGP +SAVTAFARSLGDTATRLDRIEPDLNEATPGDPRDTTTPDGMVTSLAALTVDGSLSPASTR +QFADWMLANKTGDTRLRAGVPRDWRVGDKTGTGAYGTANDIAILYPPNRKPVIVSVYITE +TEATIDDRNAAIADVGRALA--- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum oryzae TaxID=286727 RepID=A0A5A9G1E5_9PROT +--ALAGKMTELEARSGGRLGVAVLDTANGKLH-GWRGDERFPMCSTFKFLLAAAILKTVD +QGKDRLDRRIPVTKADLVPYAPFAETRLNGTPTVAELCEAAMTLSDNVAANLLLPGIGNP +AGLTAFMRGIGDKTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMERILVGDVLRPDSRR +QLIDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAIVWPEGRAPLLVACYLTQ +TAEGFKQQDSIHAEVARTVA--- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. PAMC 28711 TaxID=1795631 RepID=A0A126ZLY4_9BURK +--DLKAALQRIEQASGGRLGVCMLDTASGRRI-GYRAAERFPMCSTFKLLAAARVLHRVD +AGQEELARAVTVARADIVPHSPLTEPHVGGTMTLGALCEATITQSDNAAANLMLASFGGP +TALTAYVRSLGDRTTRLDRNEPSLNEAIAGDPRDTTTPAAMLGLTRKLVLGDALKPASRE +QLRDWLLANKTGDRKLRAGLPAGWKVGDKTGGGAFGTNNDVGVVWPPNRPPVLVAAYLTQ +TAAALEQRDAALAAVAALI---- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A2TK51_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTETTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas citronellolis TaxID=53408 RepID=UPI000718463C +--STLERLKRLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACILARVD +RGEEQLARRIVYSQADLVEYSPASERHVGQPMSVAELCEAAITLSDNGAANLLLASLGGP +TGLTDWLRSTGDGVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDVLQAASRD +QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG +SPVPAEKRDALLAEVGRLA---- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoduganella sp. FT93W TaxID=2692177 RepID=UPI0013614818 +----AALLARLESDSGGRLGVFALNTADGQHV-QHRADERFPFCSTFKMMLAGAVLARGP +---ALLAQRVPYSNADLLPHSPVTGKHVGRGMTVAALCAATIQYSDNAAANLLIARLGGV +AAVTAFARSIGDQAFRLDRMETELNTALPGDLRDTTTPAAMAESLNRLVLGSALTTAARK +QLKDWLLGNTTGDTRIRAGVPGGWLVADKTGTGDYGSTNDIGVIWPPGQEPIVLAVYFTQ +PGKDDKARNEVIAEATRIALAAf +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000735ECBD +--ALQRGIQQLEKNAGGRLGVAVTDTADGAVF-TYRGEARFPLCSTSKVFAVAAILKKSE +SANGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARRDVLAGAAKIVASGy +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI00048A8C37 +--ALQRGIQQLEKNAGGRLGVAVTDTADGAVF-TYRGEARFPLCSTSKVFAVAAILKKSE +SANGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARRDVLAGAAKIVASGy +>[subseq from] Class A beta-lactamase n=3 Tax=Rahnella TaxID=34037 RepID=A0A5J6DYQ3_RAHAQ +--SVQQQLAALEKDSGGRLGVMLINTEDNSQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLNRRVSLTKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP +QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PQKDAKSRRDVLASAAKIVTQGy +>[subseq from] Beta-lactamase class A n=1 Tax=Burkholderia sp. SJZ115 TaxID=2572882 RepID=A0A560VI34_9BURK +--DAARQIAALESSFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAT +GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR +PGKDAKYDNATLAAVARIVTATf +>[subseq from] Beta-lactamase n=2 Tax=Yersiniaceae TaxID=1903411 RepID=A0A0H5LUL8_YERIN +haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAAAALLKKSE +TQQALMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP +AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA +QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ +PVKDAQSRREILAEAAKIAVSPf +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia massiliensis TaxID=419257 RepID=UPI00119D2E98 +haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAAAALLKKSE +TQQALMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP +AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA +QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ +PVKDAQSRREILAEAAKIAVSPf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI00050F7284 +--DAARQIAALESGFGGRVGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAT +GDARLLSSVIRYTRRDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR +PGKDAKYDNATLAAVARIVTATf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8RMW4_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTETTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] class A beta-lactamase n=1 Tax=Caballeronia sordidicola TaxID=196367 RepID=UPI0004D03980 +--SAEDQLKQLESNAGGRLGVAALNTADGKRV-DFRADERFPLCSTFKLVLVSAVLEQSA +LQKGLLDRRIHYTQSELLSWAPITKKQIATGMTVAELCAAALQYSDNTAANLLMKLVGGP +ETVTAFARSIGDNQFHLDRWEPELNTAIPGDPRDTSTPTAMAQSLQRVALGDALGASQRS +QLQTWLLGNTTGAGKIAAALPAHWMIGDKTGSGDYGTTNDIGVLWPPGKPPVVLTIYLTQ +REQDAKARNDVVASATRIVVGAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0F7VH92_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLVELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Collimonas arenae TaxID=279058 RepID=A0A561FTU4_9BURK +---IARQLRQIEIRSGGRLGVAILDTLTGQSH-AYRGDERFPMCSTFKLLAAGLTLKRVD +QGQEQLARRIRYEAAELVPYSPITEKHVGGGMSMAELCEATLTLSDNTAANLLLHSFGGP +ARLTAYVRSLDDKVTRLDRIEPDLNQATPGDPRDTTSPVAMLSTMHQLLMGNALSADSRK +QLTTWLLANKTGDKRLRALLPAGWRVGDKTGSGAYGSTNDIGILFPPDRAPLLVASYLTA +TKASEAMRNAALAEVGRLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia hierapolitana TaxID=1128676 RepID=A0A561T5F0_9PSEU +--AVADRLAELERRFDSRLGLYALDTGSGREL-AHRADERFAMCSVFKALAAAAVLHRTP +--PEYLDRRVHFSEADLIDPSPIAERHVAGGMTVRELCDAAVRYSDNAAGNLLLADVGGP +AGITEFARSLGDQVTRLDRTEPELNTAVPGDERDTTTPRAIAGTFRTLVLGDHLDPADRT +QFTEWLVGNRTGDERIRAGLPAGWRVGDKTGTGSYGTANDVAVVWPPDAAPIALAVLTSR +AAENATRDNALLAEAAAVVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB2FEE +--DLAGAFKAIEAEAGARLGVSAHDTGSDNRI-EYRQHERFAMCSTFKFLAAAAVLARVD +HEQERLERIVTYKKSDLVPYSPVTEKHVGKGMPLKAICEAAITMSDNTAGNLILDSLGGP +KGLTKYARSLGDATFRLDRRETELNEAKPGDDRDTITPSAILKDLQKTALGDALSKSSRD +QLTAWMLASKTGDKRLRAGLPKDWSVGDKTGTSDSGMANDIAVIWPPNRKPILLAVYLYD +PKGTADSRNDIHKKVAQLIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A5B8WCP8_PSEAI +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDSTEPTLNTA-PGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] class A beta-lactamase n=1 Tax=Rahnella aquatilis TaxID=34038 RepID=UPI000EACABD9 +--SVQQQLAALEKDSGGRLGVMLINTEDNSQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP +QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PQKDAKSRRDVLASAAKIVTQGy +>[subseq from] Beta-lactamase n=17 Tax=Rahnella TaxID=34037 RepID=H8P0C7_RAHAQ +--SVQQQLAALEKDSGGRLGVMLINTEDNSQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP +QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PQKDAKSRRDVLASAAKIVTQGy +>[subseq from] Beta-lactamase n=2 Tax=Saezia sanguinis TaxID=1965230 RepID=A0A433SCU1_9BURK +--DIQEQLAALERSAQGRLGVAALDMASGSTV-LYRSDERFAMCSTFKMVAVAAVLHYSM +HDDSLMAQQIVYEAADLVSYSPVTEKHAGSGMSVAQLCAAALQYSDNTAANLLVQLVGGP +QAVTAFARSVGDEVFRLDRWEPELNSAIPGDERDTTSPLAMMLSTRKLLLGDALGEAQRA +QLQDWMRGNAVGGQRIRAGVPPGWIVADKTGSGAYGVSNDVGVLWTPQQNPLVLAVFFTR +PVPDAKPDDAVVAQAARLVT--- +>[subseq from] Beta-lactamase OXY-1 n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=A0A095FAQ8_BURGA +--DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAA +GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR +PGKDAKYDNATLAAVARIVTATf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=K7QZZ2_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZC4_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLVAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRLDVLASAAKIVTD-- +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Enterobacter sp. HMSC055A11 TaxID=1715020 RepID=UPI0008A63133 +-nAIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Duganella sp. CF402 TaxID=1855289 RepID=A0A1H7PWU6_9BURK +------LLAGLEKEYGGRLGVAALNTADGRQV-LHRADERFPFCSTFKMMLSAAILSREP +---ALLKKRIKYHKSDLVSYSPVTSKHVADGMTVAELCEATLQISDNAAANLLMKQIGGP +AAVTAFARSIGDTEFRQERWETALNTALPGDVRDTTTPLAMAKSLQKLVLGEALPAAARK +QLKDWMLGNTTGATRIRAGVPAGWPVADKTGSGDYGTVNDIAVIWPPGKAPIVLAVYTTQ +PNKDDKTRPEIHGEAAKIVIEAf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. RW407 TaxID=2202894 RepID=A0A2V2SWW6_9PSED +-----ERLKQLERDSGGRLGVAVLDSGDGRRF-GLREDERFPLCSTFKLLLAAAVLARVD +RGEEQLARRIVYGRGDLVPYSPVSERHVGKPLSVAELCEAAITLSDNGAANLLLASLGGP +AGLTDWLRSTGDEVSRLDRNEPTLNEALPGDPRDTSTPRAMVATLQRLLLGDVLQPASRA +QLDAWLAANKTGDKRIRAGLPPLWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG +SPASAEKREAVLAEVGRLA---- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Shigella sonnei TaxID=624 RepID=UPI00080825E6 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=10 Tax=Bacteria TaxID=2 RepID=A0A127T7D6_9BACT +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella oxytoca TaxID=571 RepID=Q8RSU5_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase OXY-2 n=15 Tax=Bacteria TaxID=2 RepID=BLO2_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q30B66_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTESTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2H4H177_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDRTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255) TaxID=323098 RepID=Q3SVS3_NITWN +---FVEELKRLENQTGGRLGVALLDAGTGQHV-GHRMDEPFPMCSTFKVLAAGALLQGVD +AGKEDLARRIYFNEADLVAHSPETRKHVGPTMTVAELCKAAITLSDNTAGNLLLASIGGP +QGLTAFARRLGDEVTRLDRIETELNESVPGDPRDTTTPSAMAANLRALALGDVLSVKSRT +QLVGWLVANTTGDKRLCAGLPAGWRAGDKTGTGERGTANDVAVIWPPDRAPFVVTAYLTG +ATVPADRQNAVMAAIGRAVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000BBD0B4C +--DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAT +GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR +PGKDAKYDNATLAAVARIVTATf +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KT62_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPHDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAAIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTS2_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAVNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAVAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000DC3834E +--ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDAHFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAINKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARKDVLAGAAKIVASGy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q5U8Y9_PSEAI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLDRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=5 Tax=Enterobacteriaceae TaxID=543 RepID=B8XLJ7_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLDRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Cellvibrio japonicus (strain Ueda107) TaxID=498211 RepID=B3PDF2_CELJU +-tQLETPFQSLEQQHRGRLGIAALDTHTGKRI-AYRALECFAMCSTFKVILAGAILAQST +QQKGLLDKRIHYTAQDLVPYSPITEQHLHTGMTLGELCTASLQYSDNTAANLLMHQLGGP +QAVTAYARTLGDNDFQLERWETALNSAIPGDKRDTTTPQAMLHSLQQLTLGNALASQAQT +QLITWMKGNTTGNKRIRKALPQGWQAGDKTGSGDYGTSNDIAILFPPKRKPILLAIYFTQ +PTQDAPWNNDVIVEASRLVLQ-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=A0A1E3EFK2_BRAEL +-qQLQQEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRVD +RGESSLDQQIRFEAKDILANSPVTKEHVASGMTLAELCEAAITRSDNTAGNMILREIGGP +AGLTGFFHTIGDNVSRLDRWELALNEGVSGDPRDTTSPVAMLKNLQRVVLGDVLQTVSRQ +KLVDWMVANKTGDARLRAGVPRDWRVADKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMEKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=A0A4Q4JUJ3_BRAEL +-qQLQQEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRVD +RGESSLDQQIRFEAKDILANSPVTKEHVASGMTLAELCEAAITRSDNTAGNMILREIGGP +AGLTGFFHTIGDNVSRLDRWELALNEGVSGDPRDTTSPVAMLKNLQRVVLGDVLQTVSRQ +KLVDWMVANKTGDARLRAGVPRDWRVADKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMEKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase class A n=1 Tax=Serratia fonticola TaxID=47917 RepID=A0A542BQU4_SERFO +--ATQQKLADLEKRSGGRLGVALINTADNSQI-HYRGNERFAMCSTSKVMAVSAVLKQSE +TQKNLLNRRVEIKKSDLVNYNPITEKHLDTGMTLAELSAATLQYSDNTAMNKLLSTLGGP +AKVTQFARSIGDVTFRLDRPEPELNTAIPGDERDTSSPLAMAKSLHNLTLGNALGEPQRA +QLIAWMKGNTTGAESIRAGLPATWVVGDKTGSGDYGTTNDIAIVWPENRAPLILVTYFTQ +PQQDAKGRKDVLAAATKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia cypriaca TaxID=882449 RepID=A0A543GFB9_9PSEU +-----DRLAELEQRFDARLGVYAVDTGTGREL-AHRADERFAMCSVFKALAAAAVLHRTP +--PEYLDERVRFTQADLVDPSPVAAQHVADGMTIRELCDAAVRYSDNTAGNLLLADVGGP +PGITAFARSLGDQVSRLDRAEPELNTAIPGDERDTTTPRAIAGSFRALVLGDHLDPADRD +LFTQWLVGNTTGDERIRAGMPPGWRVGDKTGTGSYGTANDVAILWPPDGAPIALAVLTSR +AAEDATRDYALLAQAAAVVAQ-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ34_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIRPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013D3E6A7 +-nDVQQKLAALEKSSGGRLGVALIDTADNAQT-SYRANERFAMCSTSKVMAAAAVLKQSE +TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRHLTLGSALGETQRA +QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ +PEQKAESRRDVLAAAAKIVTDGy +>[subseq from] Beta-lactamase n=17 Tax=Bacteria TaxID=2 RepID=D3INY1_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520FUS7_9BURK +----ADSLAALETDTGGRLGVMALDTASGRQV-AHRAQERFALCSTFKVLAAAAVLRDGT +---ASLGQRVRYRREDLVTYSPVTGKHVTEGMTVGELCAAALQYSDNTAGNLLIDRLGGP +AAVTAYARSIGDASFRLDRRETELNTAIPGDPRDTGTPGSMARNLQRLLLGDALPPAGRA +QLEAWMRGNTTGATRIRAGVPGGWAVADKTGAGDYGVVNDIGIAWPPDRAPIVLAIYFTQ +ERKDAPMRSEVVATAARIAVN-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0K0WRK7_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKPIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] FONA family class A beta-lactamase n=1 Tax=unclassified Serratia TaxID=2647522 RepID=UPI00046AF204 +-nTIQQQLADLEKSSGGRLGVALIDTADNSQI-LYRADERFAMCSTSKVMAVSALLKQSE +TDKNLLDRRMAIKQSDLVNYNPIAEKHLDTGMTLGEFSAATIQYSDNTAMNKILEHLGGP +AKVTTFARSIGDKTFRLDRTEPTLNTAIPGDERDTTSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPAKWIVGDKTGSGDYGTTNDIAVIWPSNNAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTEGf +>[subseq from] Beta-lactamase n=3 Tax=Klebsiella oxytoca TaxID=571 RepID=Q8RT60_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLILVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQF6_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSGLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum rubrisubalbicans M1 TaxID=1078773 RepID=A0A0U3LLP2_9BURK +--AISARLARLEADIGGRLGVSLVDTVGARQW-GYRADERFPMCSTFKWLAAAAVLRRVD +EGREQLTRRIVYHQRDLMPYSPTTGKHVDGTLSLAQLCEAAVTLSDNTAANLMLASMGGP +AGMTAFVRTLGDALTRLDRNEPTLNQAVPGDPRDTTTPAAMTADLQRLVLGDALTPTSRA +QLTQWLLANQTGDKRVRAGLPAGWKVGDKTGTGRLGTANDVGVAWTPQGKPLLFAVYLTE +NAADDARRDALHAEVGRLIAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium soli TaxID=553447 RepID=UPI00124554D4 +-eALRRRFAEIEARSGGRLGVGVLDLQTGLRA-GHRAEERFPLCSTFKLLAAAAVLARVD +AGRESLERRVTYNAADLVAYSPVTEPRVGEGMALEALCAAAITLSDNTAGNLLLSAIGGP +SGLTAYLRSLGDPVTRLDRTEPDLNEARPEDPRDTTTPGAMLDTLQRLLRGSALSDASRA +RLLGWLRDNKTGATRLRARLPADWRVGDKTGTGENGTANDVGLLAPPVGEPILVTAYLTG +STASSEARNAAIAEVAQAL---- +>[subseq from] Beta-lactamase n=1 Tax=[Pseudomonas] mesoacidophila TaxID=265293 RepID=A0A2A4FJL4_9BURK +-----TSLAELERAVGGRLGVCALDTATGRRV-EHRAGERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTVRQTDPVGWSPVTKKHVGTSMTVGELCEATAQYSDNGAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWELELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPPGWQVGDKTGTGDYGTLNDIGVLWPPARGPIVLTVYYTQ +AHADAKRDDGVIVAATRIAI--- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A0M4FF82_KLEOX +--AIHQKLTALEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Roseomonas genomospecies 6 TaxID=214106 RepID=UPI0011F2B2E3 +-kRLDDAIAALETRSGGRLGVAVLDTGTGQRF-GRRADERFPMCSTFKFLLAGAILKRVD +EGRERLDRRIPVTKTDLVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVDGP +AGLTAFLRTLGDTQTRLDRNEPSLNSAIPGDPRDTTTPTAMVHSMERLMLGDALTPASRG +QLVAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDVAIVWPEGRAPLLIASYLTE +TADGFKERDAIHAGVARAVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000B60AC7C +--ALQRGIQQLEKNAGGRLGVAVTDTADGAVF-TYRGDARFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLIRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARKDVLAGAAKIVASGy +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=UPI0012F7C557 +--SAEAQLAALESSVGARLGVAALDTGSGARV-LHRATERFALCSTFKAMLAAAILARSA +RDGSLLERRVSYGKSDLLPNSPITEKNLGQGMTVSALCAATMQYSDNAAANLLMKILGGP +AAVTAFARSIGDQSFRLDRWETELNSAIPGDLRDTTTPEAMAASLQRLVLGDALGAAQRS +QLEAWLLGNTTGATRIRAGVPADWKVGDKTGLGSYGSNNDTGVLWPPAGAPVVLAVYLTF +PREDAPARNDVIASAARIVVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas indica TaxID=137658 RepID=UPI000BABE246 +-eAFERRLARIEDDIGGRLGVALLDLGTGLRA-GWRQDERFPMCSTFKFLAAAAILARQD +QGLDSLERRVKFAAADLVEYSPGTGPRADGEMTLAELCEAAVTLSDNTAGNLMLNSLGGP +EGLTAFARSLGDDITRLDRYETALNEALPGDPRDTTTPAAMLADMRELLLGTALSPASRE +RLLGWLVANKTGDARLRAGLPKDWRVGDKTGSGDRGTANDIAILWPPRREPMLVTVYLTG +SDADMNRRNAAIAEVGKLISD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=K7QSJ9_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGHLGGP +EKVTAFAHSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Collimonas fungivorans TaxID=158899 RepID=UPI0007786C8A +---VTRQLRQIEAKSGGRLGVAILDTASGQSH-AYRGDELFPMCSTFKLLAAGLTLHRVD +QAQEQLARRIRYETAELVPYSPATEKHAGGDMSVAELCEATLTLSDNTAANLLLHSFGGP +TQLTAYLRSLGDKVTRLDRIEPDLNQATPGDPRDTTSPSAMLSTMQQLLLGNALSADSRK +QLATWLLANKTGDKRLRALLPAGWRVADKTGSGAYGSTNDIGMLLPPGRAPLLVAAYLTG +TKASEATRNATLAEVGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodoplanes serenus TaxID=200615 RepID=UPI0012D71CE1 +-eTLAAAFARIERESGGRLGVAVRDTGAGLRA-GHREDERFPLCSTFKLVAAAAVLARVD +AGRERLDRRVAIPRDGLVTYSPVTERHAGEEMTLEALCEAAMVLSDNTAGNLLLEAIGGP +AGLTDFARSLGDPVTRLDRIEPFLNESAPGDPRDTTSPAAMLETVRRLALGDALAAGSRE +KLVAWMVGNRTGDARLRAGVPAGWRVGDKTGTGDRGTANDVGVIWPPGRPPVVVAVYLTE +TEAAPAVRNGAHAAVARAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTR7_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYGDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=C0L620_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYGDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. T529 TaxID=2491343 RepID=A0A3P3ETY2_9BURK +--KAEAQLAALERSVGGRLGLVAFDTATGARV-QHRATERFPMCSTFKMMASAAILARSS +REPGLLERRVSYARSDILPNSPITEKHLGQGMTVSALCAATIQYSDNAAANLLMKILGGP +SAVTEFARSIGDPVFRLDRWETELNSAIPGDPRDTTSPEAMAASLQRLVLGDGLGAAQRS +QLEAWLLGNTTGATRIRAGVPADWKVGDKTGAGSYGTVNDIAVLWPPAGAPLVMAVYLTF +PTPDAQGRNDVIASAARIAAD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTL6_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVIAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sp. SH219 TaxID=1074433 RepID=G3EPW0_9ENTR +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDRTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIV---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia sp. ESBL53bB15_13_1E TaxID=1535134 RepID=A0A0A0R6B0_9ESCH +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAK------ +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0001C05D21 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTESTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q938A8_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A0M4FPH5_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1Z1VNS7_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDDVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=A0A481S261_KLEVA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEHGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=J7II96_ENTCL +--SVEQKLAALEQRSGGRLGVALIDTADGSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SQHDLLNQRIEIKKGDLTNYNPIAEKHVGGSMSLSELSAAALQYSDNVAMNKLIAQLGGP +QGVTAFARKIGDETFRLDLTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDAQRA +QLVTWMKGNTTGTASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLVLVTYFTQ +PQPEAESRRDVLASAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) TaxID=339670 RepID=Q0B7G1_BURCM +----ATSFAALEHAAGGHLGVCAIDSASGRRA-QHRADERFPFCSTFKAMLGAAVLAHSV +ERPGLLQQRVTYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA +QFVAWLRGNKVGDKRIRAGVPAGSQVGDKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ +TRADAKPKDDVIAAAARIAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. WS11 TaxID=1105204 RepID=A0A2P8KSB2_9BURK +---LARQLAEIEKKVGGRLGVHVLDTADGRRA-GHRQDERFALCSTFKFLAAALVLARVD +QGKERLDRRVTYARDDLVPYSPATEKHAGGEMTMAQLCEAAVTLSDNTAANLMLASFGGP +AGLTAYMRSLGDTHTRLDRIEPGLNEARAEDPRDTTTPAAIVDSMQKTLLGNALAPASRV +RLLQWLDDNKTGGQRIRAGLPADWKVGDKTGTGENGATNDIAILRPPGRAPVLLSVYLTE +TKSSMADRNAAHAAVAAAAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=A0A3G3LGS6_BURGA +--DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKLVLVSAVLARAT +GDARLLSSVIRYTRRDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR +PGKDAKYDNATLAAVARIVTATf +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000D737A48 +--ALQRGIQQLEKNAGGRLGVAVNDTADGAVF-TYRGEARFPLCSTSKVFAVAAILKKSE +SANGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARRDVLAGAAKIVASGy +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum robiniae TaxID=2014887 RepID=A0A246WTY0_9BURK +--AFVNKMARLEADAGARLGVSIVNTGSGQAW-GYRADERFPMCSTFKFLAAAAVLKRVD +RGEERLERRIVYGKEILQEYSPTTAKHVGGDMSISQLCEAAMTLSDNTAANLMLDTMGGP +AGLTAFIRTLGDGETRLDRNEPTLNESIPGDPRDTTTPAAMTADLRRIVLGDALNPASRM +LITDWLVRNKTGDKRVRAGLPASWKVGDKTGTGDQGSTNTVGVIWPPTGAPLLFAVYLTE +TRASDTVRNGVHAAVGKLIAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. FT92W TaxID=2666085 RepID=UPI0012AF1F4C +---PQDQLAALERSAGGRLGVAVLDTGSGKQV-LHRAGERFAFCSTFKTMVAAAILARGT +KEPDLLARRIHYTKADLVTYSPATEQHVADGMTVAALCEAAIQLSDNSAANLLMKILGGP +QAVTAYARAIGDQEFRLDRWETELNTAIPGDARDTTTPAAMMQSVNRLLLGDALGAPQRK +QLVDWMVGTVTGNERIRAGSPAGATVADKTGTGSYGVTNDIGVVWPKGKAPVVVVVYYTG +TDKDSKARSDVIASATRIAL--- +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI00066522B9 +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella oxytoca TaxID=571 RepID=Q8RLU6_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI0003B214CE +--ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLIRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARKDVLAGAAKIVASGy +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. AG702 TaxID=2183907 RepID=UPI000D71653F +--ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLIRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARKDVLAGAAKIVASGy +>[subseq from] Beta-lactamase n=31 Tax=Enterobacteriaceae TaxID=543 RepID=A0A4Q0DL01_ECOLX +-nDVQQKLAALEKSSGGRLGVALIDTADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA +QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ +PEQKAESRRDVLAAAAKIVTDGy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=A0A345IT66_BURPY +-----DALAALERSAGGRLGVCAIDIASGRRV-AHRQDERFPFCSTFKAMLSAAVLARSV +ERPALLQQRVTYTRADLVNYSPVSEQHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP +PAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGDALPAAQRA +QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSGAPIALAVYYTQ +ARADAR----------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sp. SH223 TaxID=1074434 RepID=G3EPW1_9ENTR +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRAEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIV---- +>[subseq from] Beta-lactamase n=1 Tax=Hahella chejuensis (strain KCTC 2396) TaxID=349521 RepID=Q2SJQ2_HAHCH +--QLEKVFAKLEERLDARMGVMVLDTQTGRTW-GQRGQERFPLCSTFKVLACAALLAKVD +AGEENLERRVPIHARDIVTYSPVTKDRIGGEMTLRELCQAAMTKSDNTAANLVLKAVGGP +PRLTEYLRGLGDETTRLDRWETELNEATPGDPRDTTSPAAMASTLQTLFLNSPLSRASRQ +QLTAWFLANETGDAKLRAGLPQDWRIGDRTGGGAYGSTNDVAVIWPPGREPLIVTVYITE +TEAAFDDRNKAIADVGRAVGAAf +>[subseq from] Beta-lactamase n=1 Tax=Rhodovulum sp. PH10 TaxID=1187851 RepID=J5PPT3_9RHOB +---LAETFAALEQQSGGRLGVALLDTRTGARA-GHRADERFPMCSTVKLLVTGATLAKVD +RGDDRLDRTIPVAESDLLAHAPVTRRHAGGDMTVEALCAAAMTVSDNTAANLLLDALGGP +AGATAFVRSLGDTVTRLDRKEPALNEALPGDPRDTTTPKAMLADLDALALGNALAPPSRE +KLVGWMVANETGGARLRAGVPDGWRVGDKTGAGGNGTSNDVAIFWPPGRPPVLVAVFLTG +SSAPPARRDEIIAAVGRAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium macuxiense TaxID=1755647 RepID=A0A109JNN0_9BRAD +-qRLQEEFARIELATSGRLGVAVLDMETGLRA-SRRGDERFPMCSTFKVLASAAVLHRVD +RGESSLDQRVQFEAKDILANSPVTKEHVASGMTLAEICEAAITRSDNTAGNMILREIGGP +AGLTSFFRTIGDNVSRLDRWEVALNEGVSGDPRDTTSPVAMLKSLQRVVLDDVLQAASRQ +KLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPRRKPIVVTVYLTG +ASAPMDKCNEVIANVARAVAA-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=UPI000D701DFA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGSRGIIAALWPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Rhodoplanes elegans TaxID=29408 RepID=A0A327JY80_9RHIZ +--DLADDFARIERDSGGRLGVAVIDAATGART-GHRADERFAMCSTFKLLLAAAVLARVD +AGRETLDRRIPIDPAALLDWAPLTRPNAGGTMTVAALAEAAMVMSDNTAANLLLDTLGGP +LGLTAWLRLLGDPVTRLDRTEPTLNEALPGDPRDTTTPAAMAADIERLVLGDALSPASRD +TLTGWLVGNRTGAARLRAGLPKDFRVGDKTGTGERGATNDVGLFWPPERRPVIVAVYLTE +TTAPAAARDATIAAVAKAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2I6SSC9_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTLRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTP3_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRALLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8KQ72_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Rugamonas sp. FT107W TaxID=2692168 RepID=UPI00136E9988 +-----ALLAKLEADSGGRLGVAAMNTADGRRL-LHRADERFPFCSTFKMMLSAAVLAK-- +-GPALLKKHVRYSKADMVTYSPVTEKHIGRGMTVAALCEATIQTSDNTAANLLMKQIGGP +AAVTAFARSIGDMEFRLDRMETELNTALPGDPRDTTTPASMVESLHKLVLGDGLGAAQRK +QLKDWMLGNTTGDTRIRAGVPAGSQVADKTGTGDYGTTNDIGVIWQPGKAPVALVVYLTQ +PGKDDKARSEVIAEATRIVVEAf +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum robiniae TaxID=2014887 RepID=UPI0009A235A8 +--AFVNKMARLEADAGARLGVSIVDTGSGQAW-GYRADERFPMCSTFKFLAAAAVLKRVD +RGEERLERRIVYGKEILQEYSPTTSKHIGGDMSISQLCEAAMTLSDNTAANLMLETMGGP +AGLTAFIRTLGDGETRLDRNEPTLNESIPGDPRDTTTPAAMTADLRRIVLGDALNPASRM +LITDWLVRNKTGDKRVRAGLPASWKVGDKTGTGDQGSTNTVGVIWPPTGAPLLFAVYLTE +TRASDTVRNGVHAAVGKLIAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Chromobacterium sphagni TaxID=1903179 RepID=A0A1S1WY95_9NEIS +----GARLARLEKDFGGRLGVFAIDTADGATL-GHRAGERFPFCSTFKAMLAGAILARSE +RQPQLLAQRIHYQKSGLVEYSPVTERHLEDGMTVAELCAATVQYSDNSAANLLLQLLGGP +AELTAYMRSIGDGSFRLERWEPELNGAIPGEERDTTTPQAMAQSLRQLALGDGLASPQRR +QLVDWLCGNTTGAEKIKAGVPADWLVGDKTGAGRYGSSNDIAVLWPQGRPPIVLAVYTTQ +PRRDAKPRHDVVASAARIVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000232305A +--ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTCLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARKDVLAGAAKIVASGy +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI00051DEE3A +--ALQRGIQQLEKNAGGRLGVAVTDTADGAVF-TYRGEARFPLCSTSKVFAVAAILKKSE +SADGLMSEKIAIHKTDLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP +QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ +QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDKHAAARRDVLAGAAKIVASGy +>[subseq from] class A beta-lactamase n=1 Tax=Rugamonas sp. FT81W TaxID=2692166 RepID=UPI00136B1977 +-----ALLAKLEADSGGRLGVAAMNTTDGRRL-LHRADERFPFCSTFKMMLSAAVLAK-- +-GPALLKKRVRYSKADMVTYSPVTEKHIGQGMTVAALCEATIQTSDNTAANLLMKQIGGP +AAVTAFARSIGDMEFRLDRMETELNTALPGDPRDTTTPASMVESLHKLVLGDGLGTAQRK +QLKDWMLGNTTGDTRIRAGVPPGSQVADKTGTGDYGTTNDIGVIWQPGKAPVALVVYFTQ +PGKDDKARSEIIAEATKIVVEAf +>[subseq from] Extended spectrum beta-lactamase CTX-M n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQE6_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVPKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRT +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000755CE41 +----DASLAALERDAGGRLGVCAIDAATGRRV-QHRADERFAFCSTFKAMLSAAVLARSI +ERPALLRERVTYRKADLVTYSPVTERHVGSGMTVAELCAATVQHSDNSAANLLMKLIGGP +QAVTAFARSIGDDMFRLDRWETDLNAAMPDDPRDTTTAGAMAASLRVLALGDALPLRQRA +QFVAWLRGNTTGDRRIRAGAPAGWPVGDKTGTGGYGTTNDIGVVWPPARGAIALAVFYTQ +ARADAKPNEHVIAEATRIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium embrapense TaxID=630921 RepID=UPI0009FD38A9 +-qRLQDEFARIELATSGRLGVAALDMETGLRA-SLRGDERFPMCSTFKALASAAVLLRVD +RGESSLDQRVRFEAKDILANSPVTKDHVESGMTLAELCEAAITRSDNTAGNMILREIGGP +AGLTAFFRTIGDNVSRLDRWELALNEGVSGDPRDTTSPVAMLKNLQRVVIGDVLQAASRQ +KLADWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMEKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase (Fragment) n=9 Tax=unclassified Escherichia TaxID=2608889 RepID=A0A0A0QZM8_9ESCH +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAK------ +>[subseq from] Beta-lactamase n=1 Tax=Rhodoplanes roseus TaxID=29409 RepID=A0A327KWQ7_9RHIZ +---MAEAFARIERESGGLLGVAVIDTGSGARS-GHRADERFAMCSTFKLLAAAAVLARVD +AGKDALDRTIRIEETALVEYSPLTKPHVGGEMTLEALCEAAMVVSDNTAGNLLLESLDGP +AGFTAWVRTLGDAVTRLDRIEPHLNEAAPGDPRDTTTPAAMAANLQKLALGTMLPLPLRD +KLTGWLVGNRTGDTRLRAGVPRDWRVGDKTGTGERGSTNDVGILWPPNREPIVVAVYLTE +TTAAPEARNAVIAAVGKAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas viridiflava TaxID=33069 RepID=UPI000F031C9C +---AIQRLKQLETTFAGRLGVVALNTGNGEVL-SYRGDEPFPLCSTFKAMLAGAILQRSV +LTPGLLDERITYRKSDLVSYSPVSEKHVQDGMTVAELCAATVQYSDNSAANLLMKLLDGP +EGLTTFARSIGDHHFRLERWETELNSAIPGDLRDTTTPLAMAHSLQRLVVGDALPESQRQ +QLQTWLRGNTTGATRIRAGVPANWQVGDKTGTGDYGTTNDVAVLWPPGKAPVVLTLYLTQ +TSKDASPRNETLAAATRVVVD-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=unclassified Escherichia TaxID=2608889 RepID=A0A0A0R787_9ESCH +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAK------ +>[subseq from] Beta-lactamase n=2 Tax=Noviherbaspirillum humi TaxID=1688639 RepID=A0A239JQV1_9BURK +------RLEELEKAFGGRLGLFALDTGSGASL-GYRDAERFPLCSTFKVMAAAALLRASE +RRPGLLAQRVHYRQSDLVEYSPLTEGHVDDGMTVAALCAAAIQYSDNTAANLLLQVLGGP +DEVTAFTRSIGDARFRLDRWETALNSAIPGDPRDTSTPAAMATSLQRLVLGEALAPAQRS +LLRDWLRGNTTGAARIQAALPARWIIGDKTGTGSYGTANDVAVLWPLRRAPIVLAIYSTH +PQEDAKGRSDIVAAAARIAVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. A1 TaxID=148446 RepID=UPI000469EAD3 +--DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFPLCSTFKVVLVSAVLARAT +GDARLLSSVIRYTRRDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAHARSIGDATFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR +PDKGAKYDNATLAAVARIVTATf +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI0007DE1B65 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEANKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella oxytoca TaxID=571 RepID=E0WC50_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKNRKEVLAAATKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=W0FF77_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGHTHGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2I4JT62_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTSSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia massiliensis TaxID=419257 RepID=UPI0011A775B0 +haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAAAALLKKSK +TQQALMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP +AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLMLGDALAKSQRA +QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ +PVKDAQSRREILAEAAKIAVSPf +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007937AC6 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNLIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rahnella sp. WP5 TaxID=1500266 RepID=UPI0005617CD2 +--SVQQQLAALEKDSGGRLGVMLINTEDNSQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP +QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVSLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PQKDAKSRRDVLASAAKIVTQGy +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q8RSU3_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGGGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=[Erwinia] teleogrylli TaxID=1384589 RepID=UPI00073D4546 +---AQQQLQALESAAGGRLGVYAIDTASGKTV-AWRADERFPFCSTFKTIAASALLKRSE +SAPDFLNQRIHYSHSDIVNWSPVTEKHLSEGMTLAELSAAALQYSDNTAVNLMVDALGGI +DKVNEFARSIGDNTFRLDRRETELNSAIPGDERDTTTPAAMSHSLQKLALGNALGETQRS +QLVTWMKGNTTGARRIQAGVPSTWTVADKTGAGDYGTTNDIAVIWPEQGGPLVVSIYYTR +EQQNSPINNDIIAAATRIAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A0M5JAJ8_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGGGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A2I4KG55_ENTCL +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTSSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. TSA6c TaxID=709813 RepID=A0A2U1WFA9_9PROT +--AFAARMTELEGRTGGRLGVAVLDSANGRLH-GWRGDERFPMCSTFKFLLAAAVLKTVD +QGKDRLDRRIPVTKADLVPYAPFSETRLNGTPTVAELCEAAMTLSDNVAANLLLPGVGNP +AGLTAFLRGIGDKVTRLDRNEPALNTAIPGDPRDTTTPAAMVRSMERLLVGDVLRPESRK +QLTDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAILWPEGRAPLLVASYLTH +TAKDFKQQDAIHADVARAVA--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTU5_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRALLILVTYFTQ +PQPRAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Photorhabdus australis TaxID=286156 RepID=A0A1C0U8Q6_9GAMM +--SLHKQLAELENSAKGRLGVTLINTANGQAI-QYRGDERFPFCSTFKLIVVAAVLHKSM +SQSELLAKHISYSEADLLSYAPIARKHLKQGMSITQLCAATLQYSDNTAANLLIKELGGV +EAVNDFTQSLGDHTFRLDRWEPDLNSAIPDDPRDTTTPAAMATSVNKIVFGEVLAVSQRG +QLIDWLKGNTTGDASIRAGVPTGWVVGDKTGSGDYGTTNDVAILWPPKGAPVVLAVYFTQ +HQQDAESRRDVLASATRLVMEH- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=J7I3K6_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMGSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase CTX-M-5 n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=BLC5_SALTM +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYLADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKASDLVNYNPIAEKHVNGTMTLAELGAGALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNSAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKCWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDVLAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14) TaxID=323097 RepID=Q1QR11_NITHX +---FVDELKRLETESGGRLGVTLLDTGTGQCV-GHRMDERFPLCSTFKVLASGAVLQGVD +AGKESLARRIYFNEADLVTHSPETHKRVGPIITVAELCKAAITLSDNTAGNLLLASIGGP +QGLTAFVRKLGDDVTRLDRIETELNEAAPGDPRDTTTPNAMASDLRALAVGDVLSAKSRA +QLVGWLAANTTGGKRLRAGLPAGWRVGDKTGTGERGTANDVAVIWPPDRAPFIITAYLTG +ATVSADRQNAVMAAVGRAVAT-- +>[subseq from] hypothetical protein n=1 Tax=Paenibacillus daejeonensis TaxID=135193 RepID=UPI000373BDDC +---------NAAEEQGVRVSVNIQDLSGNQRL-SLGSTESYMPASTIKLALATALMQQVD +KGDLSLTDEVEVSPSDVVGGTGSLQKETPQQVTLERLARLMITQSDNTATNVLIDVV-GL +DTVQQLMDELGLTVMHLGRKMFAPAP--TPEQDNYIDASDLTTLLEEVYQGDVLSEASSE +QLITWMSEQEV-DTKFGSALP-QAPIAHKTGENAN-VTHDAGYFLVPGRE-LAISVLTQV +TTEAQAIGNPIVQRIAKAVYNY- +>[subseq from] hypothetical protein n=1 Tax=Paenibacillus daejeonensis TaxID=135193 RepID=UPI000373BDDC +------------SERGIRVSVAIKDLSGSKEL-HLGSRQPYMPASTIKLALATALMQQVD +KGELSLSNEVEVSPSDVVGGTGSLQKETPQQVTLERLARLIITQSDNTATNVLIDVV-GL +DTVQQLMDELGLTVMHLGRKMFAPAP--TPEQDNYINAADLTTLLEEIYQGDVLSEASSE +QLITWMSEQEV-DTKFGSALP-QAPIAHKTGENAN-VTHDAGYFLVPGRE-LAISVLTEV +TTEAQAIGNPIVQDIARTVY--- +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum seropedicae TaxID=964 RepID=A0A5B8E7R3_HERSE +--ALTARLSRLEADIGGRLGVSLLDTASGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD +QGQEQLTRRIVYQKQDLVPYSPTTGKHTGGALSMAQLCEAAMTLSDNTAANLMLASMGGP +AGLTRFVRTLGDELTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ +QLTQWLIANQTGAKRVRAGLPASWKVGDKTGTGRLGTANDIGVVGTAQGAPLLFAVYLTE +NAATDAGRDAVHAEVGRLI---- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2P9E4L3_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASVIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q5DUK0_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFAHSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium guangzhouense TaxID=1325095 RepID=A0A4Q0RCQ9_9BRAD +-----EAFEQLELKCAGRLGVSVLDTTTGAQI-HHRGDERFPMCSTFKVLAAAAILKGVG +SKLEGLERRVRIEQADLVEYSPVTSKHVGGDMSLRELCEAAITMSDNTAGNALLKNIGGP +AGLTSFARSLGDKTTRLDRIETELNEATPGDPRDTTTPNAMATNFRRLLLGDVLLTEGRD +QLGKWLIANKTGDSRLRAGVPKGWRVGDKTGAGEHGTTNDVAIVWPPERSPVIIAAYLTG +SALDPNGRNDVIASVGSAIAK-- +>[subseq from] Beta-lactamase n=2 Tax=Variovorax paradoxus TaxID=34073 RepID=T1XD52_VARPD +--SAEAQLAALERSVGGRLGLVAFDTATGARV-QHRATERFPMCSTFKMMASAAILARST +REPGLLERRVSYGRSDILSNSPITEKHLGQGMTVSALCAATIQYSDNAAANLLMKILGGP +SAVTAFARSIGDPVFRLDRWETELNSAIPGDPRDTTSPEAMAASLQRLVLGDGLGAAQRS +QLEAWLLGNTTGATRIRAGVPADWKVGDKTGAGSYGTVNDIAVLWPPAGAPLVMAVYLTF +PTPDAAGRNDVIASAARIAAD-- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum palustre TaxID=2044885 RepID=A0A2B8BEF0_9PROT +--AFAARMTELEGRTGGRLGVAVLDSANGRLQ-DWRGDERFPMCSTFKFLLAAAVLKTVD +QGKERLDRRIPVTKADLVPYAPFSETRLNGTPTVSELCEAAMTLSDNVAANLLLPGVGNP +AGLTAFLRGIGDKVTRLDRNEPSLNTAIPGDPRDTTTPAAMVRSMERLLVGDVLRPESRK +QLTDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAILWPEGRAPLLVASYLTH +TAKDFKQQDAIHADVARAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2S1T3T0_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYTDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Gha TaxID=1855318 RepID=A0A1I3J4I0_9BRAD +----VEAIKQLELKSGGRLGVSVLDTATGTPI-HHRGDERFPMCSTFKVLAAAAILKDVG +SKLEGLERRVRIEQADLVEYSPVTSKHVGGGMSLRELCEAAITMSDNTAGNALLKNIGGP +AGLTSFARSLGDQMTRLDRIETELNEAAPGDPRDTTTPNAMAANFSRLLLGDVLLPEGRE +QLGKWLIANKTGDTRLRAGLPRGWHVGDKTGAGEHGTTNDVAIVWPPERSPLVIAVYLTG +ASLDPNGRNDVIAAVGREV---- +>[subseq from] Beta-lactamase n=1 Tax=Chimaeribacter californicus TaxID=2060067 RepID=A0A2N5E243_9GAMM +--TLAAQLAELERSANGRLGVALIDTGSQREI-TYRGEERFAMASTFKVLAAGAVLQHSV +TQPDLLAKRIRYDRAALLSYAPVTGKHLAEGMTVAELCAAAIEWSDNTAANLLLTEIGGP +QRITKLARSLHDDKTRLDRWEPALNTAIPGDERDTSTPQAMARNLQHLALGDALPPAQQQ +QMIGWLKNSQTGAKSIRAGVPAGWEVGDKTGSGDYGTTNDLAIIWPPHGKPLVLAIYFTQ +PKADAEARRDVLATATRQVLAAf +>[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. CCM 8733 TaxID=2609282 RepID=UPI00141ECFA8 +--DAQARLAALEAAAGGRLGVGALDTGDGRRL-GHRADERFPMCSTFKAIAAAAILAHGK +NVPGWLDQRVRYTKADLVTYSPITENHVDDGMTVGALCAATIQYSDNAAANLLMALIKGP +GGVTGFARSVGDTVFRLDRWETELNTAIPGDPRDTSTPAAMAALLRRVALDDGLPPAQRD +QLQNWMRGNTTGDTRIRAGVPAGWPVADKTGTGAYGSSNDIGIVFPPKGAPVVLALYYTQ +AYPQAKANSEILAAATRIVMGAf +>[subseq from] class A beta-lactamase n=1 Tax=Chelativorans sp. lm93 TaxID=2681485 RepID=UPI001358C063 +-nQLRERIAALEKQSGGRLGLALLDTRSGTSI-AHRADERFAMCSTFKLLACAAVLARVD +AGKERLDRRIVYSKVDLVEWSPVTEKHADGSMALADICEAAMTLSDNTAGNLLLQSLGGP +AGLTAFARSLGDEVSRLDRYETALNDVSPGDPRDTTTPAAMLSNLRKIVLGTALSAPSRK +QITQWLLANKTGDRRLRAGLPSGWRVGDKTGTNRD-GANDIAIAWPPDRAPIVISAYLAE +MDVPMRERDAVIEKLGAIAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6Z9G4_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLPNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAA------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2S1VVP0_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTPPRAVAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000E2E41E2 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVAYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0002C5E13C +--ETLVKVKDAEDQLGGRVGYIELDLASGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTAASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A159ZLT4_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDHVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Massilia sp. PDC64 TaxID=1881046 RepID=A0A1G6UC65_9BURK +--AAARALADLERRAGGRLGVAAWRRGGAQAI-AWRDDERFPFCSTAKVMVVATVLAQAS +RTPGLLDERVRYRKTDLVSWSPVTERHVDDGMTVADLCAAALQVSDNSACNLLLDRIGGP +AAVTAFARRVGDTAFRLDRRETDLNTAIPGDPRDTTTPRAMAKSLEALLLEQALAPEARR +RLLDWMLANTTGKERIQAGFPADWRVADKTGTGAYGTTNDVGIVFPPQGQPVIVAIYYTG +SSPDAQSDSKVAADAAAIVAR-- +>[subseq from] Beta-lactamase n=3 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A0M4G457_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKNRKEVLAAATKIVTE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=A0A345IT61_9BURK +----ATSFAALEHAAGGRLGVCAIDSASGRRA-QHRADERFPFCSTFKAMLGAAVLAHSV +DRPGLLQQRVTYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPSAQRA +QFVAWLRGNKVGDKRIRAGVPAGSQVGDKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ +TRADAKPKDDVIAAAARIAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Bosea sp. DSM 18164 TaxID=1881058 RepID=A0A1I1LKN9_9BRAD +-eEVRAALFALDRKHGGRLGVAILDSGNGRIV-AHRGEERFAMCSTFKFVAAAFALARVD +RGEEELERRVSYSKADLITYSPVTEKHVDKGLTVAEICDAAVTLSDNTAGNLLLDSFGGP +KGLTEYMRSLGDEASRLDRREPELNEARTGDPRDTTTPVAMAGVLRQTVLGAALSPASRQ +QVTAWLVANKTGDKRLRAGVPKGWRIGDKTGTGNNNATNDIGVIWPPGRAPLVVTAYYTE +SRSSFPEREAVLAEVGRLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2I8ANM0_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKTGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Aurantimonas sp. 22II-16-19i TaxID=1317114 RepID=A0A1X0T1M1_9RHIZ +--AITETIAAVEKRLGARVGAMIVDTQSGQTW-SHRAQERFPLNSTFKAFACAAVLAEVD +AGKAALDQHITFTADDLVTYSPVTEQRVETGMTLGEICDAAMTTSDNTAGNLVIESLGGP +DGVTRFMRQIGDAETRLDRTEPTLNEAAPGDLRDTTTPEAAATSLRELVLGDALSPRSRR +QLEAWLLGNKVGDPLLRAGLPKDWTIADRTGAGGHGSRSIVAIAWPPERKPVVAAIYLTG +TEASMEARSAAIAEIGTAIAR-- +>[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=A0A0C5C269_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLRNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000BF218AD +--DAARQIAALESSFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAA +GDARLLSSVIRYMRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR +PGKDAKYDNATLAAVARIVTATf +>[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=B2CMB0_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000DE02F34 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYCDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=Citrobacter sedlakii TaxID=67826 RepID=Q93PQ0_9ENTR +-qQVQKKLAALEKQSGGRLGVALINTADNSQV-LYRADERFAMCSTSKVMTAAAVLKQSE +THDGILQQKMTIKKADLTNWNPVTEKYVGNTMTLAELSAATLQYSDNTAMNKLLAHLGGP +GNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLRKLTLGDALAGPQRA +QLVDWLKGNTTGGQSIRAGLPAHWVVGDKTGAGDYGTTNDIAVIWPEDRAPLVLVTYFTQ +PQQDAKWRKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZRE8_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAARIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRR-------------- +>[subseq from] Beta-lactamase n=1 Tax=Pantoea allii TaxID=574096 RepID=A0A2V2BQP3_9GAMM +--ALQRDIQQLEQTAGGRLGVAVTDTADGAVF-TYRGNTRFPLCSTSKVFAVAAILKKSE +TASGLLNENVTIHKTDLVNYNPITEKHVGATMTVAELSAAALQYSDNAAMNKLLTRLGGP +QKVTRFARSIGDTTFRLDRTEPDLNTAIPGDKRDTTSPAAMMQSLQKLVLGSALAPAQRQ +QLSDWMKGNTTGANSLRAGLPADWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDPHAASRKAVLAGAAKIIASGy +>[subseq from] Beta-lactamase (Fragment) n=7 Tax=unclassified Escherichia TaxID=2608889 RepID=A0A0A0R7A2_9ESCH +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAK------ +>[subseq from] Beta-lactamase (Fragment) n=11 Tax=unclassified Escherichia TaxID=2608889 RepID=A0A0A0R200_9ESCH +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAK------ +>[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. CCM 8734 TaxID=2609283 RepID=UPI00141EC5F7 +--EAQAELAALEAAAGGRLGVGAIDTGDARRL-GHRADERFPMCSTFKAIAAAAILAHGK +NVPGWLDQRVRYTKADLVTYSPITEQHLDDGMTVGELCAATIQYSDNAAANLLMAMIGGP +GGVTGFARSMGDTVFRLDRWETELNTAIPGDPRDTTTPAAMAALLRRVALDDGLPAAQRD +QLQNWMRGNTTGDTRIRAAVPASWAVADKTGTGAYGSSNDIGIVFRPKGGPVVLALYYTQ +ADAQAKANSDILAQATRIVMAAf +>[subseq from] Beta-lactamase n=2 Tax=Yersinia frederiksenii TaxID=29484 RepID=A0A0T9UJT5_YERFR +haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAASALLKKSE +TQKGLMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP +AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA +QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILATYFTQ +PVKDAQNRREILAEAAKIAVSPf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A0M3R8A5_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLDINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKNRKEVLAAATKIVTE-- +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B4E83C7 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVLYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Massilia sp. MC02 TaxID=2561931 RepID=A0A4Y9SIT0_9BURK +------ELAKLEAKAGGRLGVAAYEAGKAPRV-AHRADERFPMCSTFKTMAAGAVLKRSA +TDAGLLTRRVTYAKSDLVTYSPITEKHVAEGMTVAELCAAALQYSDNTAGNLLMQLVGGP +QGVTAFARSIGDEVFRLDRWETALNTAIPGDERDTTSPAAMARSYERLLLGDALPPAQRM +QLRDWMLGNTTGASRIRAGVPPEWKVADKTGTGDYGTTNDAGIAWPAADRALVMVIYFTQ +PSKGADAQSGVIAEAARLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Nitrobacter vulgaris TaxID=29421 RepID=A0A1V4I2E9_NITVU +heKFVDELKRLENESGGRLGVTLLDTSTGQRV-GQRMDERFPMCSTFKVLAAGAVLQGVD +AGKENLSRRIYFSETDLVTHSPETQKHVGPHMTVAELCKAAITLSDNTAGNLLLASIGGP +QGLTAFVRGLGDDMTRLDRAETALNEALPGDPRDTTTPNAMASDLRALVLDGMLSAESRA +QLAGWLAANTTGGKRLRAGLPAAWRVGDKTGSGERGTANDVAVIWPPDRAPFIVTAYLTG +ATASADRQNAVIAAVGRAVTTAf +>[subseq from] Beta-lactamase n=6 Tax=Yersinia enterocolitica TaxID=630 RepID=BLAC_YEREN +--SVDKQLAELERNANGRLGVAMINTGNGTKI-LYRAAQRFPFCSTFKFMLAAAVLDQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLIKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTARPNDPRDTTTPAAMAASMNKLVLGDALRPAQRS +QLAVWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASVTKIILS-- +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI000327E34D +--SVDKQLAELERNANGRLGVAMINTGNGTKI-LYRAAQRFPFCSTFKFMLAAAVLDQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLIKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTARPNDPRDTTTPAAMAASMNKLVLGDALRPAQRS +QLAVWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASVTKIILS-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodospirillaceae bacterium SYSU D60006 TaxID=2268029 RepID=UPI000E65A649 +-dELAAEFARIEREVAGRLGVAVLDTMSGEAA-GHRSDERFPLCSTFKLLAGAAILARVD +AGEESLERRIQFGAGDLVTYSPATEKRTGEPMTLAELCEAAITLSDNTAGNLLLETLAGP +AGFTAYARSLGDSATRLDRIEPALNEAIPGDARDTTTPAAMTANLNALILGDALSSASRN +RLTHWMIANKTGDARLRAGLPKDWRVGDKTGSGDRGTTNDIGVAWRPDQGPIIIAAYLTQ +TTAPTDQRNAALAAVARAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A515L5U7_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTSSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007DDDAED +-pETLVKIKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Class A beta-lactamase RAHN-2 n=2 Tax=Rahnella TaxID=34037 RepID=E3U909_9GAMM +--SVQQQLTALEKESGGRLGVMLINTEDNSQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLNRRVSLTRSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP +QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PQKDAKSRRDVLASAAKIVTP-- +>[subseq from] Class A beta-lactamase n=1 Tax=Massilia lutea TaxID=321985 RepID=A0A4V0Z2Y9_9BURK +---ADAGFAAIERDLKGRLGVAAIDTATGKIV-GNRLDERFPMCSTFKAILAAQALHRAA +REPGFLERRLRYARADLVSHSPVTGKHVDTGMTVAELCAATVQYSDNTAANTLMKELGGP +AGLTAFARGLGDEAFRLDRWELALNSAIPGDERDTTTPLAMARTLQKLVVGTALPAPQRQ +QLKDWLLGNTTGGNRLRAAVPAAWQVGDKTGTGTYGVTNDIGIVYPPGRAPLVVVVFTHR +DDKEADAREDVVADAARAAIR-- +>[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. SAP-35 TaxID=2703883 RepID=UPI00140B41B7 +----EARLARLEQASGGRLGVAAIHTGDGRVL-AHRGDERFPFCSTFKMMLAAAVLARDP +---ALLTKRIRYTKDDLVPHAPVTARHLDDGMTVAELCAATLQYSDNPAANLLMKQIGGP +AAVTAYARSIGDAEFRQERWETELNSAIPGDPRDTTTPAAMARSLHKLVLGDALPPPQRQ +QLKDWMLGNTTGATRIRAGVPAAWPLADKTGAGDYGTVNDIAVVWPPGAAPIVLAVYLTQ +PGKDDKIRPEFHGEVAKIVIEAf +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas knackmussii TaxID=65741 RepID=UPI001362523F +-kALEAQLAKLELDSGGRLGVAVLDTGTGQGF-GHRADERFPMCSTFKALLAAAVLARVD +AGKEDLARHIVYGREALVDYSPVAEKHVGEPLSVAELCKAAVTLSDNGAANLLLESLGGP +AGLTAWLRTTGDTVTRLDRNEPALNEGTPGDPRDTTTPTAMLETLQRLLLGDVLKLGSRD +QLKAWLLANQTGNARIRAGVPKDWKVGDKTGTGPTGTSNDIAILYPPGRSPILVTAYLTR +STASPQQQDKVLAEVGRLAAK-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8KMX4_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI0008FD5C8B +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRCIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase class A n=1 Tax=Massilia flava TaxID=871742 RepID=A0A562PGY1_9BURK +-------LADIERDLHGRLGVCALDLGSGKTV-GHRQDERFPMCSSFKALLAAQALARAA +REPGFLDKRLRYAKADLVSYSPVTEKHVEQGMTVAELCTAVVQVSDNTAANTLMKELGGP +AALTAWVRGLGDPTFRLDRWETELNTAIPGDERDTTSPLAMARTLGKLVTGDALPAAQRE +QLKQWMIGTTTGDRRIRAAAPAGWTVGDKTGTGNYGVTNDIGFLLPPGRAPIVIVVYMHQ +PALEAKTREDIVAAATRAAL--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=A0A345IT64_BURGA +--DAARQIAALESSFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAA +GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR +PGKDAKYDNATLAAVARIVT--- +>[subseq from] Class A beta-lactamase Sed1 n=2 Tax=Citrobacter sedlakii TaxID=67826 RepID=UPI000181D192 +-qQVQKKLAALEKQSGGRLGVALINTADNSQV-LYRADERFAMCSTSKVMTAAAVLKQSE +THDGILQQKMTIKKADLTNWNPVTEKYVGNTMTLAELSAATLQYSDNTAMNKLLAHLGGP +GNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLRKLTLGDALAGPQRA +QLVDWLKGNTTGGQSIRAGLPAHWVVGDKTGACDYGTTNDIAVIWPEDRAPLVLVTYFTQ +PQQDAKWRKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=Q4TZY8_PROMI +-nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKGLLSQRVEIKPSDLVNYNPIAEKHVNGTMTFGELIAAALQYSDNTAMNKLIAHLGGP +DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA +QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGGYGTTNDIAVIWPEGRAPLVLVTYFTQ +SEPKAESRRDVLAAAARIVTDGy +>[subseq from] class A beta-lactamase n=1 Tax=Rhodanobacter thiooxydans TaxID=416169 RepID=UPI000D387319 +---ASARLVALERRHGGRLGVAVLDTGSGRRI-GHRVDERFAMCSTFKLLAAAAVLARVD +RGVERLERRVVFDKDALVTYSPVTSHRVGAPMTMAELCHAAITMSDNTAGNLLLHSLGGP +AGWTAYARSLGDGVSRLDRIETELNEARPGDPRDTTTPAAMLANLHALLLGTALSDASRG +QLAGWLRANTTGDARLRAGVPAGWRVGDKTGSGNHAATNDVAIIWPPQRKPLLVAAYYAE +STADADARNVVLAEVGRIAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia TaxID=629 RepID=UPI0010FF0F93 +haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAASALLKKSE +TQKGLMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP +AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA +QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ +PVKDAQNRREILAEAAKIAVSPf +>[subseq from] Beta-lactamase CTX-M-6 n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=BLC6_SALTM +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYVADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIRASDLVNYNPIAEKHVNGTMTLAQLGAGALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNSAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWGVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDVLAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=Q9LAC0_PROMI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=10 Tax=Enterobacteriaceae TaxID=543 RepID=G1CCP7_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI000A10048B +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Rhodopseudomonas palustris TaxID=1076 RepID=A0A0D7EIM5_RHOPL +-----AAMKRIEASSGGRLGVAVLDSASGARM-GYRDNEAFPMCSTFKVLAAGAVLTQVD +AGHARLSDRVRFTRDAVVTYSPITKDRIGGEMTLAELCDAAIRYSDNTAGNLLLGQIGGP +PGLTQFARTLGDPVTRLDRTETDLNEAGPGDPRDTTTPAAMLSNLKNLVLGSALSESSRD +QLVAWLKGNTTGGTRLRAGLPTDWVVGDKTGSGGRGSTNDIAVIWPAERKPIVVTAYLTG +TEAPAEQRNAALASVGRAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Phyllobacterium zundukense TaxID=1867719 RepID=A0A2N9VQX4_9RHIZ +--DLAAAFKTLEEKTGARLGVSARDTGSDNRI-DYRENERFAMCSTFKFLAAAAVLARVD +QKQEQLERMILIKKSDLVTYSPVTEKYVGKGMSIEAICEAAVTLSDNTAGNLMLDTLGGP +KALTKYARSLGDATFRLDRWETELNEAKPGDPRDTITPAAILKDLQKTMLEDALSRSSRD +QLVEWMLGSKTGDKRLRAGLPKDWNVGDKTGTSDSGMANDLAVIWPPDRKPILLAVYLYD +PKGTADSRNEIHKKVASLVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q5XLZ5_ECOLX +-nDVQQKLAALEKSSGGRLGVALIDTADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKNVLSQKVEIKSSDLINYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARAIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRHLTLGSALGETQRA +QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ +PEQKAESRRDVLAAAAKIVTDGy +>[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=B3GA03_MORMO +-nDVQQKLAALEKSSGGRLGVALIDTADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKNVLSQKVEIKSSDLINYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARAIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRHLTLGSALGETQRA +QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ +PEQKAENRRDVLAAAAKIVTDGy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI00039DA7E2 +--DAARQIAALESGFGERIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAA +GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR +PDKDAKYDNATLAAVARIVTATf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1B3ILG4_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYTDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Kluyvera sp. PO2S7 TaxID=2705459 RepID=UPI001425C4B5 +-nDVQQKLAALEKSSGGRLGVALIDTADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKKVLSQKVEIKSSDLINYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA +QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ +PEQKAESRRDVLAAAAKIVTDGy +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. JS1663 TaxID=1851577 RepID=A0A244EEW4_9BURK +-----GRLAEIEKASGGRLGVAVLDSGSGRLA-GHRQDERFPLCSTFKALAAALVLARVD +RGQETLERRVRYARDELVTYSPATEKHAGEDMTMAQLCEAAVTLSDNTAGNLMLASFGGP +AGLTAFMRSIGDAHTRLDRIETALNEARAGDARDTTTPAAMAANMQKILLGGVLSPASRA +QLMQWLDDNKTGDQRIRAGLPAGWRVGDKTGSGENGTANDVAILRPPGRAPVLLSVYLTA +TRAPMAERNATIAAVGAAAA--- +>[subseq from] Beta-lactamase n=2 Tax=Salmonella TaxID=590 RepID=Q6T5A3_SALTM +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI00068022AA +haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAASALLKKSE +TQKGLMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP +AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA +QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ +PVKDAQNRREILAEAAKIAVSPf +>[subseq from] Beta-lactamase n=1 Tax=Massilia sp. Root351 TaxID=1736522 RepID=A0A0Q6WJS8_9BURK +------AFAALEKDLGGRLGVCAINLANGRQV-GHRTGERFPVCSTFKAMLAGAILQRSA +SDATLLNRRIGYTRQDLVPHAPITEKNLAQGMTVAELCAATVQYSDNPAANLLMKVLGGP +EAVTAFARSIGDTAFRLDRWETELNSAIPGDPRDTTTPLAMMRSLQALVVGDALPAPQRQ +QLKDWLVGNTTGGKLIRAGTPAGWTVGDKTGGGAYGARNDVAVIWPPGQAPIVIAVYTAH +NKEDAGYREDIIAGAASAAI--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobiales bacterium 62-17 TaxID=1895810 RepID=A0A1Q4BCJ7_9RHIZ +--QLTTQFRHIERDSKGRLGIFVLDTQRDRYV-GYRQGERFPMCSTFKLVLAAAVLKRAD +QGKEKLDRPIPVKASDIVPNSPGTEKKVGDSMTLAELCAATTTLSDNAAANLILATLGGP +KGMTAFARSIGDTAFRLDRIEPMMSNATPRDLRDTTTPQAMAETVQKLVLGDVLSEASRA +QLTAWLVGNKTGDTRLRAGVPGDWRVGDKTGAGGHGTTNDVGLFWAPQRKPIIVSVYLTG +SRATSDERNAAIAAVARAVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. OXWO6B1 TaxID=1835724 RepID=UPI0009EE1EA1 +--ALQRDIQQLEQTAGGRLGVAVTDTADGAVF-TYRGNTRFPLCSTSKVFAVAAILKKSE +TASGLLNENVTIHKTDLVNYNPITEKHVGATMTVAELSAAALQYSDNAAMNKLLTRLGGP +QKVTHFARSIGDTTFRLDRTEPDLNTAIPGDKRDTTSPAAMMQSLQKLVLGSALAPAQRQ +QLSDWMKGNTTGANSLRAGLPADWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDPHAASRKAVLAGAAKIIASGy +>[subseq from] Beta-lactamase n=2 Tax=Yersinia massiliensis TaxID=419257 RepID=A0A0T9RGU3_9GAMM +haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAASALLKKSE +TQKGLMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP +AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA +QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ +PVKDAQSRREILAEAAKIAVSPf +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia TaxID=629 RepID=UPI00067E5F04 +haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAASALLKKSE +TQKGLMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP +AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA +QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ +PVKDAQSRREILAEAAKIAVSPf +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI001432DFD0 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETSCLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodoplanes piscinae TaxID=444923 RepID=A0A3S4B147_9RHIZ +-eTLAAAFARIERESGGRLGVAVRDTGSGLRA-GHREDERFPLCSTFKLVAAAAVLARVD +AGQERLDRRVAIPPRDLVTYSPVTERHAGEEMTLAALCEAAMVLSDNTAGNLLLEAIGGP +AGLTDFARSLGDPATRLDRIEPFLNESVPGDPRDTTTPAAMLETVRRLALGDALAAGSRE +KLVAWMVGNRTGDARLRAGVPEGWRVGDKTGTGDRGTANDVGVIWPPGRPPVVVAVYLTE +TEAAPAVRNGAHAAVARAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q6W8V8_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTESTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGSGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. Root351 TaxID=1736522 RepID=UPI0009E67E3B +-----TAFAALEKDLGGRLGVCAINLANGRQV-GHRTGERFPVCSTFKAMLAGAILQRSA +SDATLLNRRIGYTRQDLVPHAPITEKNLAQGMTVAELCAATVQYSDNPAANLLMKVLGGP +EAVTAFARSIGDTAFRLDRWETELNSAIPGDPRDTTTPLAMMRSLQALVVGDALPAPQRQ +QLKDWLVGNTTGGKLIRAGTPAGWTVGDKTGGGAYGARNDVAVIWPPGQAPIVIAVYTAH +NKEDAGYREDIIAGAASAAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas abietaniphila TaxID=89065 RepID=UPI0007826B32 +--SIEQTLAELERRHGGRLGVAILDTGHQRLI-AHRGDERFAMCSTFKALAAAYVLARVD +RKEEDLSRMIVYGKEQLVPYSPLTEKHTGEGLSVGSICEAAVTLSDNTAANLLLDSFGGP +PALTAWLRSTGDQVTRLDRREPDLNENRAGDPQDTTTPIAMLQSLRTLILGDVLSGASRD +QLIAWLVSNTTGDQKLRAGLPKGWRVGDKTGSGSNNASNDVAVIWPPNRAPLIVTVYYTG +AKATGDQINALMADVGRLVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum chlorophenolicum TaxID=211589 RepID=UPI00067A826E +----VQKMAKLESGVGGRLGVSILDTAKGRQW-GYRADERFPMCSTFKFLATAAVLKRVD +QGEERLERRIVYTKKSLVPYSPTTGKHTGGNLSMSQLCEAAMTLSDNTAANLMLESLGGP +AGLTAFIRSLGDDMTRLDRNEPTLNESLPGDPRDTTTPAAMVADLRKIVLGNALNPASRT +LITQWLLDNQTGTKRVRAGLPKGWKVGDKTGTGSHGSTNTVGVAWTPQGVPLLFAVYLTE +TDADEAKRNGLHAAVGRLIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria (strain MC40-6) TaxID=398577 RepID=B1YZ28_BURA4 +----ATSFAALEHAAGGRLGVCAIDSASGRRA-QHRADERFPFCSTFKAMLGAAVLAHSV +DRPGLLQQRVSYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPSAQRA +QFVAWLRGNKVGDKRIRAGVPAGSQVGDKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ +TRADAKPKDDVIAAAARIAVA-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. KBS0801 TaxID=1179675 RepID=UPI00110D3BED +----ATSFAALEHAAGGRLGVCAIDSASGRRA-QHRADERFPFCSTFKAMLGAAVLAHSV +DRPGLLQQRVSYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP +SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPSAQRA +QFVAWLRGNKVGDKRIRAGVPAGSQVGDKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ +TRADAKPKDDVIAAAARIAVA-- +>[subseq from] Beta-lactamase n=4 Tax=Morganellaceae TaxID=1903414 RepID=Q9R429_MORMO +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=12 Tax=Bacteria TaxID=2 RepID=Q9EYX1_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGGRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2R3NWP2_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMISTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A1YTM6_PROMI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMISTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000C1BEC70 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000FA94ECB +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013314893 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. CG3 TaxID=1075768 RepID=UPI0004764BCE +-----AQLAELEKTLGGRLGVFALDTGDGSQL-SHRAGERFAFCSTAKVMIASAILARSA +QVAGRLRQRVRYAKGELVNYSPITERHVGDGMTVAELCAAGIQYSDNTSANLLIKILGGP +AAVTAYARSIGDTTFRLDRLETELNSAIPGDPRDTTTPEAMGLSLRRVALGDALAPASRE +LLQDWLRGNTTGAKRIRAAVPADWQVGDKTGTGDYGTANDVGVVWRPNRAPVVVSIYTTH +AEKDAKASDEVIAAAARIVV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1W6AL57_KLEPN +--DVQQKLAELERQSGGRLGVALINTAXNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAXNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFXQ +PQPKAESRRDVLASAXKIVTN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium 2SD TaxID=2502200 RepID=UPI0010F6827A +--KVREALFALDRKHGGRLGVAILDSGNNRIV-AHRGEERFAMCSTFKFVAAACVLSRVD +RGEEELERRVSYSKDDLITYSPVTEKHVEKGLTVAELCDAAVTLSDNTAGNLLLDSFGGP +KGLTDYMRSLGDEASRLDRREPELNEARQGDPRDTTTPVAMAGVLRQTVLGGALSPASRQ +QLTAWLVANKTGDKRLRAGVPKGWRIGEKTGTGNNNATNDIGVIWPPGRAPLVVTAYYAE +ASVAFPEREAVLAEVGRLV---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Neisseria gonorrhoeae TaxID=485 RepID=A0A0A0VDI5_NEIGO +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPATMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A097BQV9_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTAPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASGAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=Q6PP90_PROMI +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. CF444 TaxID=1144319 RepID=J2LRH1_9BURK +---VVSQLAKLEASVGGRLGVDIVDSATQRRW-GYRADERFAMCSTFKFLACAAVLKRVD +AGQERLDRRIIYGNDVLVAYSPTTGKHAGGDLTLAQLCEAALTLSDNTAANLILQSLGGL +EPFNQFVKSLGDKQTRLDRFETELNTAIPGDSRDTTTPAAMSDNLQRILLGDVLSPASRE +QLIAWMRRNKTGDRRVRAGMQPGWTVGDKTGSGDYGTTNTIAIIWPPQGKPLLASIYLTR +TKAPEDRRNAVLAEVGKIIV--- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000C7DA77F +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] hypothetical protein n=1 Tax=Paenibacillus chibensis TaxID=59846 RepID=UPI000FDA9143 +----------AAEAHGVGVSVDIKDLSGHETI-ELGSQDAYYSASIIKLALIATLMQEVD +SGQHSLDEKLTVKPEDVVGGAGSLQKKFPQDVTIGRLAKLMIIQSDNTATNALIGLV-GF +DKVNAFIKSQGFTITHLGRKMMTPAKS--PAEDNYASAPEMLTLLDRIYNAEVVSAKSRD +QILEWMKAQEV-NTKFGAVLR-GKPIAHKTGELGY-VSHDVGYFLIPGR-EIAIAVLTKV +LKKAEEQGNPYVQRIAKATYNY- +>[subseq from] hypothetical protein n=1 Tax=Paenibacillus chibensis TaxID=59846 RepID=UPI000FDA9143 +----------TAESKGIRVSVGIKDLSGGAEV-HLGSLQSYMPASTIKMALVSTLMQQVD +KGALTLDQKVTVKPDDVVGGTGSLQKETPQDVTIERLARLMITQSDNTATNVLIDVV-GL +DKVQALMDQLGLQTMHLGRKMFAAA--PTPEQDNYIDAADLVTLLAKIYNHEFLSAQSSN +QIISWMKAQEV-NTKFGAALP-DAPIAHKTGENAN-VTHDVGYFLVPGH-EIAISVMTEV +TTEAQAIGNPVVQSIAKAVYS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacteriaceae bacterium TaxID=1849603 RepID=A0A2Z4N5Y1_9ENTR +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=6 Tax=Enterobacteriaceae TaxID=543 RepID=A0A5X8L928_SALTM +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2P9E9T4_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSVLPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacteriaceae bacterium TaxID=1849603 RepID=A0A2Z4N600_9ENTR +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=C4NV37_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter sp. 50677481 TaxID=1736699 RepID=A0A0V9JS97_9ENTR +-qQVQKKLAALEKQSGGRLGVALINTADNSQV-LYRADERFAMCSTSKVMTAAAVLKQSE +THDGILQQKMTIKKADLTNWNPVTEKYVGNTMTLAELSAATLQYSDNTAMNKLLAHLGGP +GNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLRKLTLGDALAGPQRA +QLVDWLKGNTTGGQSIRAGLPARWVVGDKTGAGDYGTTNDIAVIWPEDRAPLVLVTYFTQ +PRQDAKWRKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Raoultella sp. NCTC 9189 TaxID=2583577 RepID=A0A509C742_9ENTR +heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD +AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAELCAAAITLSDNTAANLLLASVGGP +QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLTGSVLSAASRQ +QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMEERNRQIAEIGETLVKHw +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Enterobacteriaceae bacterium TaxID=1849603 RepID=A0A2Z4N5Y6_9ENTR +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q2V899_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAEPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A378CM31_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. B21 TaxID=2607496 RepID=A0A5A9FAU2_9PROT +---LAERLAALEERTGGRLGVAVLDTGSGRLQ-GWRVDERFPMCSTFKFLLAAAVLKAVD +QGKERLDRRIPVTQADMVPYAPFAEKRLNGTPMVAELCEATMTLSDNVAANLLLPGVGDP +AGLTAFLRGFGDKTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMERLLVGDVLRPDSRR +QLADWMIANKTGDKRLRAGVPAGWRVGDKTGTGTNGTANDIAILWPENRPPLLVASYLTQ +TAKDFKQHDSIHAEVARAVA--- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007E5319C +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00061469B4 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Shigella flexneri 4c TaxID=1617964 RepID=A0A0C5PJE3_SHIFL +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Beijerinckia sp. 28-YEA-48 TaxID=1882748 RepID=A0A1H4WRC5_9RHIZ +--KLDAAFRQIERDSGGRLGVFVLDTQSGLHA-GCRQNERFPMCSTFKLVLAAAVLKRVD +QGKETLDRRIHIAATDIISNSPATEKHVGDTMTLAELCEATTTLSDNAAANLILATLGGP +QGMTAFARSIGDKVLRLDRFETAMSDARPGDKRDTTSPQVMTETIQKLVLGDVLSEASKT +QLIAWLVGNKTGDTRLRAGVPKDWRVGDKTGTGGYGTTNDIGLFWPPHRKPIIVSAYLTG +SKATSDERNATMAAVARAIAT-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0006CA6B0D +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000F51B019 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0011196DCD +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI001072A181 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6B9ANM2_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM-94 ES-beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00062CAFEA +--ETLVKVKDAEDQLGGRVGYIELDLASGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTAASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. SRS16 TaxID=282217 RepID=UPI001316118E +--DLPAQLAEIERGSGGRLGVGVLDTATGQRA-GHREDERFPMCSTFKLLASALVLARVD +RHEERLERRVLFGARDLVDGSPITGQHVGGNMTMAELCEAAITRSDNTAGNMLLASFGGP +KAFTTYARSLGDTLTRLDRNETSLNEARPGDPRDTTTPAAMLGNLQKILVGDALSPSSRA +QLLRWLDANKTGDERMRARLPAGWKVGDKTGSGERGATNDIGILRPPGRAPILVTIYLTE +TEAPANARNATIASAGAAIA--- +>[subseq from] TEM family class A beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=UPI000FD807C4 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI000E1CF3CC +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Shigella sonnei TaxID=624 RepID=H9BJT1_SHISO +--ETLVKVKDAEDQLGARVGYIELDLNSGKIFeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0000253B3F +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQRDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q9AFC8_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTGGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A318G5R6_KLEOX +-dAIQQKLADLEKSTGGRLGVALIDTSDNSQV-LYRGDERFAMCSTGKVMAAAAVLKQSE +ADNQVLNKRLEIKKSDLVIWSPVTEKHLQSGMTLAELSAATLQYSDNTAMNKMIGYLGGP +DKVTAFARSIGDVTFRLDRTEPALNTAIPGDERDTTTPLAMAESLHKLTLGSALGEQQRA +QLVTWLKGNTTGGQSIRAGLPANWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter spathiphylli B39 TaxID=1163407 RepID=I4VWB8_9GAMM +--AVAAHLAALERQHGGRLGVAMLDTGSGQHV-GHRADERFLMCSTFKLLAAAAVLARVD +QGSEQLDRRITYGKDVLLEWAPETSRHVGAQMTVGELCQAAITVSDNTAANLLLTSLGGP +AAVTAFVRTLGDPLTRLDRIEPELNRTRPGDLRDTTTPAAMLADMQALLLGDALSPASRG +QLIEWLCGNTTGKQQLRAGLPAGWRIGDKTGSGAQQETNDIAIIWPPQRKPLLVTAYYTG +SAADKDGRHAVLAAVGRLAA--- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001111FAFB +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Salmonella paratyphi A TaxID=54388 RepID=A0A5I3QY74_SALPT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Roseomonas sp. CQN31 TaxID=2184016 RepID=A0A317F9S8_9PROT +--QLEAALREIEAARGGRLGVAVLDSASGEAA-GHRATERFPLTSTFKLLAAGAVLAQVD +AGRMRLDDRIRYRREEVVTYSPVTERHAGADMTVGQLCEATMTLSDNTAANLLLRGLGGP +AGLTAWLRGIGDDVTRLDRWETALNEARPGDPRDTTTPAAMLATMQRLTLGDVLSPGSRA +HLLAWLRANRTGGTRLRAGLPPRWQAGERTGTGPNGTSNDVGLVWPPSGAPLLVAAYLTE +GAADMATRDAALADVGASVAAAw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=O34176_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6B9A2K7_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASRVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Kluyvera georgiana TaxID=73098 RepID=Q8GNP9_9ENTR +-nDVQQKLAALEKSSGGRLGVALIDTADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA +QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ +PEQKAESRRDVLAAAAKIVTD-- +>[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=E0AF28_PSEAI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=3 Tax=Neisseria gonorrhoeae TaxID=485 RepID=UPI0007DD53FC +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0C5BXY6_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A1U9XRB9_SHISO +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A286SCJ7_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0004617675 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007DD7879 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase TEM n=320 Tax=root TaxID=1 RepID=BLAT_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007DDCCF3 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2971A2 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2U8JH98_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Neisseria gonorrhoeae TaxID=485 RepID=Q27W39_NEIGO +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=N0D6W6_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=A0A2J0QVT1_9ENTR +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010AB34B7 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=3 Tax=Proteus mirabilis TaxID=584 RepID=B9DR46_PROMI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNIGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C7C8381 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=L0GCN8_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTV +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Chromobacterium sp. F49 TaxID=1777131 RepID=A0A2R2IVY8_9NEIS +--SAAARLAALEADFGGRLGVCALDTASGAEL-GHRAGERFPFCSTFKAMLVGAVLARSA +KQPGLLAERIHYARRDLVEYSPRTEPHLADGMTVAELCAAAVQYSDNSAANFLLKLLGGP +AALTAYMRSIGDESFLLERWEPELNRAVPGEARDTSTPQAMAQSLRRLALGDALAPNAQR +QLVEWLRGNTTGAEKIRAGVPAGWVVGDKTGNGRYGSSNDIAVLWPPGRAPVVLTVFTTQ +TREDAKQRHQVVAAAARIAAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Collimonas pratensis TaxID=279113 RepID=UPI00143D0FB6 +-----EQLRQIEAKSGGRLGVAIFDSHSGQTY-AYRGGERFPMCSTFKLLASAFVLKRVD +QGKEQLTRRIRYQKADLVPYSPVTEHHTGAGMTVAELCEAAITQSDNTAANLLLHSFGGP +AQLTAYMRASGDKMTRLDRIEPHLNEAAPGDPRDTTTPSAMVSSLREILLGGNLSGTSRQ +QLTDWLLANKTGDKRLRALLPSGWRVADKTGTGDQGTANDIGMLLSPDGAPLLVASYLTG +APGPAAARDAVHAQVGRLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8KSD2_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCNAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0002513C27 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A8DZJ3_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAKTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=U3N8Z2_KLEPN +--ETLVKVKDAEDQLDARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum thiophilum TaxID=528244 RepID=A0A0F2KSK1_9PROT +----AGRMAALEKRGGGRLGVAVLDTGTGRRL-AWRGDERFPMCSTFKFLLAAAVLRTVD +RGTERLDRRIPVTKADLVPYAPFAETRLDGTPTVAELCEAALTLSDNVAANLLLPGVGNP +AGLTAFLRDLGDRKTRLDRNEPSLNTAIPGDPRDTTTPVAMTHSMERLLVGDALRPDTRR +QLTDWMIANKTGDKRIRAGLPAGWRVGDKTGTGRNGTANDIAILWPGNRPPVLVASYLTG +TAEGFKQHDAIHADVARAVVD-- +>[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=Q56H91_ENTCL +--ETLVKVEDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI00080677F1 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Bacteria TaxID=2 RepID=UPI000E292EB1 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Halomonas elongata TaxID=2746 RepID=A0A329Q237_HALEL +---LEAELASLEQRLDARLGVAVTDTGSGRHW-GHREDERFPMTSTFKVLACAALLDRVD +AGQEELQRRVIYEQDDLVTYSPVTKEHVGEPMTLGSLCEAAMGYSDNSAANMVLKAIGGP +SAVTDFTRSLGDDMTRLDRWETKLNEATPGDPRDTTTPAAMAADLQALFLGDRLLEESRE +RLTDWFLGNRTGDARLRAGLPDDWRIGDRTGSGAHGSTNNVAVAWPADGEPVIISAYLTE +FEGDMDQRNAAIAEVGKLVAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. S171 TaxID=1641860 RepID=UPI00131C51E8 +--AAEDQLKQLESSAGGRLGVAALNTADGKRV-NYRADERFPLCSTFKLMLVSAVLEQSA +LQQGLLERRIRYTQSELLSWAPITKKQIATGMTVAELCAAALQYSDNTAGNLLMKLVGGP +ETVTAFARSIGDNQFHLDRWEPELNTAIPGDPRDTSTPAAMAQSLQRVTLGDALGASQRS +QLQTWLLGNTTGADKIAAALPAHWMIGNKTGLGDYGTTNDIGVLWPPGKPPVILTIYLTQ +RKPDAKARNDVVASAARIVVGAf +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=B0JD04_ECOLX +--DTLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q93A77_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERDRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075AA0EF +----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ +ARAP------------------- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q6UK85_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDNVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Massilia sp. Root418 TaxID=1736532 RepID=A0A0Q7F4U0_9BURK +-----SAFASLEKDLGGRLGIAAINLATGKQV-GHRAGERFPVCSTFKAVLAGAILHRSV +SDPALLQRRISYTSKDMVPHAPITEKNIAQGMTVAELCAATVQYSDNPAANLLMKVLGGP +EAVTAYARSIGDTDFRLDRWETELNSAIPGDPRDTTTPLAMMRSLQALVVGDALPATQRQ +QLKDWLVGNTTGGKLIRAGTPAGWTVGDKTGGGAYGARNDIAVIWPPGQAPIVIAVYTAH +DSKDAKYREDIIAGATSAAI--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodoplanes piscinae TaxID=444923 RepID=A0A327K6Q8_9RHIZ +-eTLAAAFARIERESGGRLGVAVRDTGAGLRA-GHREDERFPLCSTFKLVAAAAVLARVD +AGQERLDRRVAIPPRDLVTYSPVTERHAGEEMTLAALCEAAMVLSDNTAGNLLLEAIGGP +AGLTDFARSLGDPVTRLDRIEPFLNESAPGDPRDTTSPAAMLETVRRLALGDALAAGSRE +KLVAWMVGNRTGDARLRAGMPEGWRVGDKTGTGDRGTANDVGVIWPPGRPPVVVAVYLTE +TEAAPAVRNAAHAAVARAVVA-- +>[subseq from] Class A beta-lactamase n=5 Tax=unclassified Herbaspirillum TaxID=2624150 RepID=A0A5F0LKQ0_9BURK +--SLVARLAKLEASVAGRLGVEILDSGSGRRW-GYRADERFPMCSTFKFLAASAVLRRVD +TGAEQLDRRIVYGEDVLVNYSPTTGKHVGGDLSLAQLCEAAITLSDNTAANLMLRSLGGL +DAFNKFVRSLGDDTTRLDRFETELNTSIPGDPRDTTTPTAMTGNLQKILLGDALSAASRR +QITAWMLANKTGDRRVRAGMQPGWKVGDKTGSGDYGTTNTVAIIWPPQGAPLLASIYLTE +TKASEEQRNTVLAEVGKLIV--- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. AM6 TaxID=2661553 RepID=A0A5K7Y3K3_9GAMM +-----SAIQAIESEVGARIGVTVLDTADGTRF-SWRGNERFPMSSTFKVLACGHLLSRVD +EGQESLSRKVAIRPADLVTYSPITEHHTRDGLTLEALCHATITTSDNTAGNLILDALGGP +AALTAYLRRLNDDSTRLDRRETALNEATPGDPRDTTTPHAMAATLQRLLVGDALSEPSRL +ALQGWMLANTTGDDKLRAALPDDWQIADKTGGGGYGTNNDVAILWPPLRAPLIVAVYLTE +SEADLAARNAAIADVGRLLVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=UPI0013E0EA56 +--TIEEQLTTLEKNSQGRLGVALINTKDNSQV-TYRGDERFAMASTSKVMAVAAVLKESE +KQSGLLDNPITIKKADLVPYSPITEKHLATGMTLAQLSAATLQYSDNTAMNKILDYLGGP +SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEQNAKYRKDIIAKAAEIVTKEf +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SK35_9BACT +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAICSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum oryzae TaxID=286727 RepID=A0A1X7EGH9_9PROT +-dALAAKMTELEARSGGRLGVAVLDSGNGTLH-DWRGNERFPMCSTFKFLLAAAVLKTVD +QGKDRLDRRIPVTKADLVPYAPFAETRLNGTPTVAELCEAAVTLSDNVAANLLLPGIGNP +VGLTAFMRGIGDKTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMQRLMLGDVLRPDSRR +QLIDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAIVWPEGRAPLLVASYLTQ +TAEGFKQQDSIHAEVARAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Azospirillum thiophilum TaxID=528244 RepID=UPI0006987310 +----AGRMAALEKRGGGRLGVAVLDTGTGRRL-AWRGDERFPMCSTFKFLLAAAVLRTVD +RGTERLDRRIPVTKADLVPYAPFAETRLDGTPTVAELCEAALTLSDNVAANLLLPGVGNP +AGLTAFLRDLGDRKTRLDRNEPSLNTAIPGDPRDTTTPVAMTHSMERLLVGDALRPDTRR +QLTDWMIANKTGDKRIRAGLPAGWRVGDKTGTGRNGTANDIAILWPGNRPPVLVASYLTG +TAEGFKQHDAIHADVARAVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q6PP91_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLRNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=D2D0D5_RAOTE +heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD +AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAELCAAAITLSDNTAANLLLASVGGP +QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLTGSVLSAASRQ +QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMDERNRQIAEIGETLVKHw +>[subseq from] Beta-lactamase TEM n=1 Tax=Raoultella terrigena TaxID=577 RepID=A0A6D1S5A6_RAOTE +heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD +AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAELCAAAITLSDNTAANLLLASVGGP +QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLTGSVLSAASRQ +QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMDERNRQIAEIGETLVKHw +>[subseq from] Beta-lactamase class A/beta-lactamase class A CTX-M n=2 Tax=Serratia fonticola TaxID=47917 RepID=A0A0U4IW52_SERFO +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPQAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A126E3J8_ECOLX +--ETLVKVKDAEDRLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGREQLGRRIHYSQSDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. FT135W TaxID=2692175 RepID=UPI00136E3978 +-------LARLEKESAGRLGVAALNTADGRTV-LHRADERFPFCSTFKMMLSAAILSREP +---ALLKKRIAYDKSDLVSYSPVTSKHVGEGMTVAELCEATLQISDNAAANLLMKQIGGP +AAVTAYARSIGDTEYRQERWETELNTALPGDPRDTTTPLAMAKSLQKLVLGEALPTAARK +QLKDWMLGNTTGATRIRSGVPAGWPVADKTGSGDYGSVNDIAVIWPPGKAPIVLAVYITQ +PNKDDKTRPEIHGDVAKIVIEAf +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000C810935 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTNPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=5 Tax=Enterobacterales TaxID=91347 RepID=D9U8W0_PROMI +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Hyphomicrobium sp. xq TaxID=2665159 RepID=UPI0012B957CE +--DLNARLAEIEAAAQGRLGVAILDTKTGELF-GRREFERFPLCSTFKVLAAALVLQRVD +SGEEKLDRRVVFSANDVVEYSPVTKDRAGAEMTMAELCTAAITQSDNTAGNLMLASFGGP +EALTQWLRTLGDAATRLDRTEPALNEVPPGDPRDGTTPRAMAYTLQRILLGNVLSKSSEK +LLIGWLTANTTGGARLRAGLPADWRVGDKTGTGARGATNDVAIVWPPDHPPIVIAVYLAD +TEAPIDVRNAAIADVGRATAALf +>[subseq from] Beta-lactamase n=1 Tax=Hahella sp. KA22 TaxID=1628392 RepID=A0A3T0VK73_9GAMM +--QLEKVFAKLEDRLGARMGVMVLDTQTGRTW-EQRGQERFPLCSTFKVLACAALLAKVD +AGEENLTRRVQIQARDIVTYSPVTKDRIGGEMTLGELCHAAMTKSDNTAANLVLKAVGGP +PKLTEYLRGLGDEITRLDRWETELNEATPGDPRDTTSPAAMASTLRKLFLDSPLSPASRQ +QLTNWFLANETGDAKLRAGLPQDWRIGDRTGGGAYGSTNDVAVIWPTGREPLIVAVYITE +TEAAFDDRNKTIADVGRAVGAAf +>[subseq from] class A beta-lactamase n=1 Tax=Rahnella sp. CFA14(1/10) TaxID=2511203 RepID=UPI001021A918 +--SVQQQLAALEKDSGGRLGVMLINTEDNSQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLNRHVSIKKSDLVNYNPITEKHLGKGMTIGELAAAALQYSDNTAMNKLIGQLGGP +QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVALGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPENKAPLILITYFTQ +PEKNAKSRRDVLASAAKIVTQGy +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. UNPA324 TaxID=1141174 RepID=UPI0011514958 +---LFDAVQQLEIKSGGRLGVAVLDTKTGASV-HHKGDERFPMCSTFKVLASAAILKGAG +DKLDQLDRRIRIEQADIVENSPVTREHVGPDMSLRELCEAAMTRSDNTAGNLLLKNMGGT +AGLTAFARSLGDNVTRLDRTETELNEAAPGDPRDTTTPNAMAENFRRLLFGNELMPESRD +QLAKWLIANKTGDKRLRAGLPQNWRVGDKTGAGEYGTTNDVAVVWPPLRSPLIIAVYLTG +ASLDMNGQNEVIASAGREVAREf +>[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A1P8SN36_ACIBA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli 909945-2 TaxID=1269007 RepID=V0AKS9_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPKERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM-94 ES-beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0002C5E125 +--ETLVKVKDAEDQLGGRVGYIELDLASGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTAASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001033EE7C +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASVGCGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A142EC40_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007DCF92F +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPDDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=8 Tax=root TaxID=1 RepID=Q0H0C0_ECOLX +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. meg3 TaxID=2025949 RepID=A0A223P8F3_9BURK +---IVSQLAKLEASVGGRLGVDIIDSATQRRW-GYRADERFPMCSTFKFLASAAVLKRVD +AGQEQLDRRIIYGNDVLVSYSPTTSKHVGGDLTLGQLCEAALTLSDNTAANLILKSLGGL +EPFNKFIKSLGDKQTRLDRFETELNTAIPGDPRDTTTPAAMSDNLQHVLLGDVLSPSSRA +QLIAWMRSNKTGDRRVRAGMQHGWTVGDKTGSGDYGTTNTIAIIWPPQGKPLLASIYLTR +TKAPEDQRNAVLAEVGKIIV--- +>[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=O32372_CAPOC +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Photorhabdus cinerea TaxID=471575 RepID=UPI00140E7205 +--SLHKQLAELENSAKGRLGVTLINTANGQAI-QYRGDERFPFCSTFKLIVVAAVLHKSM +SQSELLAKHISYSEADLLSYAPIARKHLNQGMSITQLCAATLQYSDNTAANLLIKEVGGL +EAVNHFTQSLGDHTFRLDRLEPDLNSAIPDDPRDTTTPAAMAASVNKIVFGEVLAALQRE +QLIDWLKGNTTGDASIRAGVPTGWVVGDKTGSGDYGTTNDVAILWPPKGAPVVLAVYFTQ +HQQDAESRRDVLASATRLVMEH- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8KMX3_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTG1_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVVMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRLDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Shigella sonnei TaxID=624 RepID=H9BJT2_SHISO +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKSSHIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI0005E085B7 +-eSLDKQLAELERKSNGLLGIAMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHIKYHESDLLSYAPITRKNLAQGMSVSELCAATIQYSDNTAANLLIRELGGI +AAVNEFARSIGDHTFRLDRLEPDLNTALPNDPRDTTTPAAMAASLNKLVLGDALPAAQRE +QLAIWLKGNTTGGETIRAGAPADWIVGDKTGGGDYGTTNDIAVLWPPTGAPIILVIYFTQ +REKDAKARRDVLAEATKMVLSH- +>[subseq from] Beta-lactamase n=8 Tax=Bacteria TaxID=2 RepID=D3KDJ9_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=Q6UVM7_ACIBA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGTSLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Cupriavidus pinatubonensis TaxID=248026 RepID=UPI0011286AEC +--DAESRLAALERSAGGRLGVFARHTGDGRQV-RHRAEERFPFCSTFKVILAGAVLQRSA +GAPGLLDEHVRYTRQDLVAYSPITEKRVADGMTIAQLCAAAIQYSDNGAANLLMHRLGGP +AAVTGFARSIGDQTFRLDRWETELNTAIPGDPRDTSTPAAMAASLQALALDGALPPVQRN +QLQAWLRGNTTGAARIQAGMPAGWQIGDKTGSGDYGTTNDIAVLWPLAGAPIVVAIYFTQ +AAPDAKWSNETIASAARIAL--- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI000D318E9D +--ETLVKVKDAEDELGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium aquaticum TaxID=270351 RepID=A0A0J6S105_9RHIZ +--DAAARLAQLERRDGGRLGVEVRDTATGRRF-GHRADELFPLCSTFKALAAAAVLARAD +KGQDDLNRRITYTRDALLSYAPVTGKHVETGMTLAELCAAAVVWSDNTAANLMLDRLGGP +AGITAFARAHGDTVTRLDRTEPTLNTAIPGDPRDTTSPAAMVGLLDTILLGQVLSAESRA +RLTGWMQESPTGLKRLRAGLPEGWRTADKTGTGDNGTANVVALIRRPDGAPILAAVYLTG +SPAEPAARDALHAEIGRLIARSf +>[subseq from] Beta-lactamase FONA-3 n=2 Tax=Serratia fonticola TaxID=47917 RepID=Q9RIR1_SERFO +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Shigella sonnei TaxID=624 RepID=UPI0007DCD4B8 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTIRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] FONA family class A beta-lactamase n=1 Tax=Serratia sp. 3ACOL1 TaxID=2448483 RepID=A0A3G2FEH8_9GAMM +--NIQQQLSELEKSSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Cobetia amphilecti TaxID=1055104 RepID=UPI000A079ACA +-----SAIQAIESEVGARIGVTVLDTADGTRF-SWRGDERFPMSSTFKVLACGHMLSRVD +EGQESLSRKVEIRPADLVTYSPITENHTRDGLTLEALCHATITTSDNTAGNLILDTLGGP +AALTAYLRRLDDDSTRLDRRETALNEATPGDPRDTTTPHAMAATLQRLLVGDALSEPSRL +ALQGWMLANTTGDDKLRAALPDDWQIADKTGGGGYGTNNDVAILWPPLRAPLIVAVYLTE +SEAELAARNAAIADVGRLLVK-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0002510F41 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Rahnella victoriana TaxID=1510570 RepID=UPI00103BBDCD +--SVQQQLAALEKDSGGRLGVMLINTADNSQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLTRRISLKKSDLVNYNPITEKHLDTGMTIGELAAAALQYSDNTAMNKLIEQLGGP +QKVTAYARTLGDSTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHATLGTALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PEKDAKSRRDVLASAAKIVMQGy +>[subseq from] Beta-lactamase class A n=2 Tax=Rahnella aquatilis TaxID=34038 RepID=H2J1V6_RAHAC +--SVQQQLAALEKDSGGRLGVMLINTEDNSQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLNRHVSLKKSDLVNYNPITEKHLNTGMTVGELAAAALQYSDNTAMNKLIGQLGGP +QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVALGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PEKDAKSRRDVLASAAKIVTQGy +>[subseq from] Beta-lactamase n=1 Tax=Yersinia nurmii TaxID=685706 RepID=A0A0T9L3L6_9GAMM +-qSLSEQLAALEEKAQGRLGVSLINTQSGKEL-QYRGNEAFPFCSTFKLVLAAAILRQSM +SQPALLEKHITYSEADLLSYAPIARENLGKGMTVAALCAAALQYSDNTAANLLIQQLGGL +EGVNKFTQSLGDTAFRLDRWEPELNSAIPGDPRDTTTPSSMAALVKKIQFGDGLAPAQQQ +QLAQWLKGNTTGNASIRAGVPAGWVVGDKTGSGDYGTTNDVAILWPPTGAPLILAVYFTQ +HKKDAESRRDVLAEATRIILAEy +>[subseq from] FONA family class A beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=UPI0013776F39 +--NIEQQLSELEKNSGGRLGVALIDTADNSQI-LYRADERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTIWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTEGf +>[subseq from] Beta-lactamase n=1 Tax=Providencia stuartii TaxID=588 RepID=A0A2S1T433_PROST +-nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKGLLSQRVEIKPSDLINYSPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA +QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGGYGTTNDIAVIWPEGRAPLVLVTYFTQ +SEPKAESRRDVLAAAARIVTDGy +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007DD737D +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFFHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=A0A5B8KR36_PROST +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=3 Tax=Gammaproteobacteria TaxID=1236 RepID=Q9AGJ5_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia lacunae TaxID=2211104 RepID=A0A370NB37_9BURK +--RIRQQLAQIEAETGGRLGVAILDTASGLHA-GLRMDERFPMCSTFKLLAAAAMLARTD +RGQEDLQRRILFSKADLLPNSPVTGEHTRERMSVADLCNAAITRSDNTAANLLLASFGGP +AGLTAFARSVGDSVTRLDRIEPTLNEAIPGDPRDTTTPNAMLGNLRELLLGERLSASSRE +QLKAWLVANQTGDERIRAKLPKDWRVGDKTGTGDRGTANDVAILWPPGRAPILVSVYLTE +TSGNAKRNNAAIAKVGALV---- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2P9EIA5_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLMRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMAERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Shigella flexneri TaxID=623 RepID=UPI0007DD5517 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSTLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=G8A3R7_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATTEERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0002F6E49C +--SVDKQLAELERNANGRLGVAMINTGNGTKI-LYRAAQRFPFCSTFKFMLAAAVLDQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLIKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTARPNDPRDTTTPAAMAARMNKLVLGDALRPAQRS +QLAVWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASVTKIILS-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea allii TaxID=574096 RepID=UPI000BB44634 +--ALQRDIQQLEQTAGGRLGVAVTDTADGAVF-TYRGNTRFPLCSTSKVFAVAAILKKSE +TASGLLNENVAIHKTDLVNYNPITEKHVGATMTVAELSAAALQYSDNAAMNKLLTRLGGP +QKVTRFARSIGDTTFRLDRTEPDLNTAIPGDKRDTTSPAAMMQSLQKLVLGSALAPAQRQ +QLSDWMKGNTTGANSLRAGLPADWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDPHAASRKEVLAGAAKIIASGy +>[subseq from] FONA family class A beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=UPI001415429B +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLGTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVT--- +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B4E83CC +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVNYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007DCE91F +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTMIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] FONA family class A beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=UPI0004217104 +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRADERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase FONA-6 n=1 Tax=Serratia fonticola TaxID=47917 RepID=Q9RIQ6_SERFO +--NIQQQLSELEKSSGGRLGVALIDTADNSQI-LYRADERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=A0A448SRU8_SERFO +--NIQQQLSELEKSSGGRLGVALIDTADNSQI-LYRADERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica subsp. enterica serovar Uppsala TaxID=2565143 RepID=A0A5I6H430_SALET +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKILLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=UPI000E069F69 +--TIEEQLTTLEKNSQGRLGVALINTKDNSQV-TYRGDERFAMASTSKVMAVAAVLKESE +KQSGLLDNHITIKKADLVPYSPITEKHLATGMTLAQLSAATLQYSDNTAMNKILDYLGGP +SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEQNAKYRKDIIAKAAEIVTKEf +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B4E8387 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSCLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEICASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Collimonas arenae TaxID=279058 RepID=A0A0A1FDD8_9BURK +---IVAQLRQIESTTGGRLGVAIFDSRSGKTY-AYRGDERFPMCSTFKLLASALVLKRVD +QGKEQLARRIRYKASDLVPYSPATEHHTGGDMSVGELCEAAITLSDNTAANLLLQSFGGP +AQLTAYMRASGDKMTRLDRIEPHLNESAPGDPRDTTTPNAMVHSLREILLGDNLSASSRQ +QLTDWLLANKTGDKRLRALLPAGWHVADKTGTGDQGTANDIGMLLPPGGAPLLVASYLTG +TKASAAARDAVHAEVGRLAA--- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI0009E3695C +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ70_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAVKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESCLDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. SJZ147 TaxID=2572896 RepID=UPI0011AAECE8 +--ALQRDIQQLEQTAGGRLGVAVTDTADGAVF-TYRGNTRFPLCSTSKVFAVAAILKKSE +TASGLLNENVAIHKTDLVNYNPITEKHVGATMTVAELSAAALQYSDNVAMNKLLTRLGGP +KKVTRFARSIGDTTFRLDRKEPDLNTAIPGDKRDTTSPAAMMQSLQKLVLGSALAPAQRQ +QLSDWMKGNTTGANSLRAGLPADWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +PDPHAASRKAVLAGAAKIIASGy +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI0006822DC1 +haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAASALLKKSE +TQKGLMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP +AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDTLAKSQRA +QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ +PVKDAQSRREILAEAAKIAVSPf +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=UPI0011D2A648 +heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD +AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAELCAAAITLSDNTAANLLLASVGGP +QGLTAFLRRSGDQTSRLDRWETELNEALPGDVRDTTTPQAMANTLRNLLTGSVLSAASRQ +QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMDERNRQIAEIGETLVKHw +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. NFACC02 TaxID=1566250 RepID=A0A1H9MK48_9PSED +--SIEQTLAELERRHGGRLGVAILDTGHQRLI-AHRGDERFAMCSTFKALTAAYVLARVD +RKEEDLSRVIVYGKEQLVPYSPLTEKHTGEGLSVGSICEAAVTLSDNTAANLLLDSFGGP +PALTAWLRSTGDQVTRLDRREPDLNENHAGDPQDTTTPIAMLQSLRTLILGDVLSGASRD +QLIAWLVSNTTGDQKLRAGLPKGWRVGDKTGSGSNNASNDVAVIWPPNRAPLIVTVYYTG +AKATGDQINALMADVGRLVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Geothrix fermentans TaxID=44676 RepID=UPI000411D01D +----PARLAALEARAGGRLGVAALDTGTGRRI-AHRGEERFPMCSTFKVLLAGAVLARVE +KGQERLDRPIAYTKSDLLEYAPVAAARLAEGMTVEALCAAAVEASDNTAANLLLQALGGP +GEVTAFARGLGDPVTRLDRTEPTLNTALPGDPRDTTTPAAMVESLKAMLLGGGLEPDSCQ +RLEGWMRGSLTGGDRLRAGLPATWTIGDKTGTGDRGTVNDVAILRPPGRAPILVAAYYTG +SRAPLKDRNAVLAEVGRIVAAAf +>[subseq from] class A beta-lactamase n=1 Tax=Jiella sp. R10 TaxID=2606717 RepID=UPI00131C4CF6 +-dALAAQLSEIEAGLGARLGVSILDTGSGKRW-EHRASERFPLCSTFKALGAAAVLARVD +TGEESLDRRVRFAASDLVTYSPVTETQAGGAMTMAEICHAAVTRSDNTAGNLILKSLDGP +AGFTRFLRSIGDAQTRLDRWETELNDVPPGDPRDTTTPAAMTDSLARVVLGDVLSPASRE +TLSGWLVANTTGDKRLRAGLPKSWRVGDKTGTGDRGVANDVAVIWPPTGAPIVASVYIAD +TTASLDARNAAFAEIAAG----- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8GD10_KLEPN +-nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA +QLVMWLKGNTTGAASIRAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLVLVTYFTQ +SEPKAESRRDVLAAAARIVTDGy +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00122E0724 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTX +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTB2_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADGRFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALRYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRGTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Kluyvera intermedia TaxID=61648 RepID=Q5MD18_KLUIN +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIQAGLPKSWVVGDKTGSGDYGTTNDIAIIWPENHAPLVLVTYFTQ +PEQKAESRRDVLA---------- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2BC059 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQQ +QLLQWMVEDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q6IT48_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERETTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI000F7067D5 +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAILKQSE +SNKEVVNKRLDINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKNRKEVLAAATKIVTE-- +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000C6C8872 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] BETA-LACTAMASE n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00001113F3 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKAGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase TEM-102 n=1 Tax=Plasmid pWW100 TaxID=167474 RepID=Q91UY8_9ZZZZ +-----VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAVGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=E5LP65_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWLIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=Q4U457_ENTCL +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGVTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1L7B531_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQVTMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7HZB6_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVMLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=B5THT3_ACIBA +--ETLVKVKDAEDQLGARVGYIELDLNSGGILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLRNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Rhodoplanes sp. Z2-YC6860 TaxID=674703 RepID=A0A127ER68_9RHIZ +--TLKAELTRIELESGGRLGVAVLDTGSGARV-DHRGDERFPMCSTFKLLGAAAVLKRVD +GGQEKLERRIVFSAKDIVANSPITEKHVGGDMTLAEICEAAMTVSDNTAGNLILKSLSGP +KGITDFARTLGDSMTRLDRFETELNEALPSDPRDTTTPLSMLGNVQKLVLGDALSAGSKD +QLTKWLLANKTGDTRVRAGLPAGWRTGDKTGSGERGTTNDIGVLWPPDGAPIVVTIYLTG +TQASAENRNATLAAVGRAIVS-- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2P9E6A6_ECOLX +------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. GW103 TaxID=1175306 RepID=I3CQ40_9BURK +--TLTDTLSRLEADIGGRLGVSLVDTAGARHW-GYRADERFPMCSTFKFLAAAAVLHRVD +QGKEQLSRRIVYHQKDLVPYSPTTGKHTGGALSMAQLCEAAMTLSDNTAANLMLASMNGP +AGLTRFVRTLGDDLTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRRLLLDDALAPASRQ +QLTQWLVANRTGDQRVRAGLPAGWKVGDKTGTGRLGTANDVGVVWTDKGAPLLFAVYLTE +NAATDARRDAVHAEVGRLI---- +>[subseq from] Beta-lactamase n=1 Tax=Kluyvera georgiana TaxID=73098 RepID=A0A291NXX5_9ENTR +-nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKDLLSQRVEIKSSDLINYNPIAEKHVNGTMTLGELSAAALQYSDNTAMNKLIAHLGGP +GKVTAFARAIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGNALGDTQRA +QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLVLVTYFTQ +PKPKAESRGDVLAAAARIVTDGy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ97_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPAAWVVGDKTDSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Polaromonas sp. YR568 TaxID=1855301 RepID=A0A1I7H6I5_9BURK +--AVSARLKALERESGGRLGVSVLDTANGARW-GHRAGERFPMCSTFKLLAAALVLHRVD +AGQEQLARKVIVKASDIITHSPTTKQYVGPQITIAQLCEATITLSDNAAANLLLATFGGP +QGLTAYTRSLGDTMTRLDRNEPSLNEATTGDKRDTTTPDAMVTTIQKIALGTVLSEASRK +QITQWLLDNKTGDNRLRALLPAGWRVGDKTGTGGHGSTNDVGILWPPGRAPLVVAAYLTG +TSRPIAQREAVLAKVGELAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum rubrisubalbicans TaxID=80842 RepID=UPI00077C3A24 +--AISARLARLEADIGGRLGVSLVDTVGARQW-GYRADERFPMCSTFKWLAAAAVLRRVD +EGREQLTRRIVYHQRDLIPYSPTTGKHVDGTLSLAQLCEAAVTLSDNTAANLMLASMGGP +AGMTAFVRTLGDALTLLDRNEPTLNQAVPGDPRDTTTPAAMTADLQRLVLGDVLTPASRA +QLTQWLLANQTGDKRVRAGLPAGWKVGDKTGTGRLGTANDVGVAWTPQGKPLLFAVYLTE +NAADDARRDALHAEVGRLIAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A2S1T3T7_PSEAI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQSTMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI0007DE0EF1 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGHEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Cobetia sp. TaxID=1873876 RepID=A0A2E4Q4C2_9GAMM +-----SAIQAIESEVGARIGVTVLDTADGTRF-SWRGNERFPMSSTFKVLACGHLLSRVD +EGQESLSRKVAIRPADLVTYSPITEHHTRDGLTLEALCHATITTSDNTAGNLILDALGGP +AALTAYLRRLNDDSTRLDRRETALNEATPGDPRDTTTPHAMAATLQRLLVGDALSEPSRL +ALQGWMLANTTGDDKLRAALPDDWQIADKTGGGGYGTNNDVAILWPPLRAPLIVAVYLTE +SEADLAARNAAIADVGRLLVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum autotrophicum TaxID=180195 RepID=UPI0012ECD314 +--SAQKKLAALEKESGGRLGVAALNTADGAQL-LHRGDERFAFCSTFKVIAASAILTRSN +ADAGLLQRRIRYTKAEMVNYSPITEKHLADGMTVAELCAAALQYSDNSAVNLLMKILGGP +EAVTAYARSIGDREFRLERWETMLNSAIPGDPRDTSTPVAMMHDLQRLVLGDALTPAQRE +QLRIWLLGNTTGATRIHAGVPAGWQVGDKTGTGDYGTTNDIGVVWPSGTAPLVIALYFTQ +NTQDAAPRNDVLASATRVVIDAf +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. Root318D1 TaxID=1736513 RepID=A0A0Q6N2I5_9BURK +--SAEAELAALESSVGGRLGVAALDTATGARV-QHRAAERFPLCSTFKTMLAAAILDRST +RDGSLLERRVSYGKGDILPHSPITEKYLGQGMTVSAMCAATIQYSDNAAANLLMKILGGP +SAVTAYARSIGDQAFRLDRWETELNSAIPGDPRDTTTPEAMAASLQRLVLGDALGAAKRS +QLETWLLGNTTGATRIRAGVPADWKVGDKTGAGSYGTVNDTGVLWPPVGAPLVLAVYLTF +PTKDAEGRNDVIASAARIAVN-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0011C9592E +------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SFO family class A extended-spectrum beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=A0A1Q5VB22_SERFO +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRADERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMVIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTSWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. TSH64 TaxID=652740 RepID=A0A2U1XMM0_9PROT +--AFAARMSELEGRTGGRLGVAVLDSANGRLQ-DWRGDERFPMCSTFKFLLAAAVLKSVD +QGKDRLDRRIAVTKADLVPYAPFSETRLNGTPTLAELCEAAVTLSDNVAANLLLPGVGNP +AGLTAFLRGIGDKVTRLDRNEPSLNTAIPGDPRDTTTPAAMVRSMERLLVGDVLRPDSRK +QLTDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAILWPEGRAPLLVASYLTH +TAKDFKQQDAIHADVARAVA--- +>[subseq from] Class A beta-lactamase SFO-1 n=5 Tax=Enterobacteriaceae TaxID=543 RepID=A0A126E3U4_ECOLX +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE +MDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAELSAAAIQYSDNTAMNKILEHLGGP +AKVTEYARTIGDKTFRLDRTEPTLNTAIPSDKRDTTSPLAMAKSLQTLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00092C7AEC +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLHNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLA---------- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5P1MSP3_ECOLX +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE +MDKNLLAKRMEIKQSDLVNYSPIAEKHLDTGMTLAELSAATIQYSDNTAMNKILEHLGGP +AKVTEYARTIGDKTFRLDRTEPTLNTAIPSDKRDTTSPLAMAKSLQTLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPATWVVGDKTGGGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RMN1_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHHTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=3 Tax=Gammaproteobacteria TaxID=1236 RepID=Q8GP08_PSEAI +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLRNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001072674F +-----VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] FONA family class A beta-lactamase n=1 Tax=Enterobacter ludwigii TaxID=299767 RepID=UPI000A3AC462 +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE +MDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAELSAAAIQYSDNTAMNKILEHLGGP +AKVTEYARTIGDKTFRLDRTEPTLNTAIPSDKRDTTSPLAMAKSLQTLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=C4PE86_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=5 Tax=Enterobacterales TaxID=91347 RepID=Q8VP43_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Brucella melitensis TaxID=29459 RepID=UPI001071E4F4 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=A0A3P0CSY7_9BURK +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA +QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWSPAGGPVALAVYYTQ +AKDD------VIAAATRIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Fulvimarina sp. TaxID=1969479 RepID=A0A2E1HKF6_9RHIZ +--AITETIAAVEKRLGARVGAVIIDTQSGRTW-SHRAQERFPLNSTFKAFACAAVLAEVD +AGKAALDKHITFTADDLVTYSPVTETRVEAGMTLGEVCDAAMTMSDNTAGNLVIESLGGP +DGVTRFMRQIGDAETRLDRTEPTLNEATPGDPRDTTTPEAAATSLRELVLGDALSPRSRR +QLETWLLGNKVGDPLLRAGLSKDWTIADRTGAGGHGSRSIVAIAWPPERKPVVAAIYLTG +TEASMEERSAAIAEIGTAIAR-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q6W7J4_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDEQNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=B6E296_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Elstera cyanobacteriorum TaxID=2022747 RepID=A0A255XSG8_9PROT +--TLTQTIIDLETRLQGRFGVLIHDTETGKRW-QHRADERFPMCSTFKYVLAAAILARVE +AGEDKLDRRLPITAADLVPYAPVTQPQVGKTLTLAELCHAAVTVSDNTAANLLLRVLGGP +AALTGFLRRIGDNVTRLDRWEPELNSALPGDPRDTTTPAAMTRTLENLLLGPALTPASKT +QLTLWLIANTTGDAKVRAGLPKSWRVGDKTGSGARGTMNDVVAIWPPQRKPVLLSLYLTE +TKASMEDRNAAFAAVGTAIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000CFE7B69 +--DAARQIAALESGFGGLIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAT +GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR +PGKDAKYDNATLAAVARIVTATf +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SHD0_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGGRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=Q8VN22_9ENTR +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIQAGLPKSWVVGDKTGSVDYGPTTHIAIIWPENHAPLVLVTYFTQ +PDQKAESRRDVLAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A4Q1UDC3_RHILE +--DIQRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTAWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTAPVKELNPVFAEVGRMIVE-- +>[subseq from] Extended spectrum beta-lactamase TEM-63 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00062CAFEF +--ETLVKVKDAEDQLGGRVGYIELDLASGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTAASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=UPI0010E5F4AD +heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD +AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAELCAAAITLSDNTAANLLLASVGGP +QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLTGSVLSAASRQ +QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPVRIVIIYLTG +TEASMDERNRQIAEIGETLVKHw +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A1B2H7A9_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDDMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2R4PD66_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +GQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q9RN48_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASQQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. FT55W TaxID=2666083 RepID=UPI0012AFAF71 +-------LARLEKESGGRLGVAALNTADGRQL-TYRADERFPMCSTFKMMAAAAILARDP +---ALLKKRIQYEKSDLVPNSPVTSKHVAEGMAVAELCEATLQYSDNAAANLLMKQIGGP +VAVTAYARSIGDNEFRLERWETELNSAIPGDARDTTTPLSMARSLHKLVLGEALPAPQRR +LLKEWMVGNTTGATRIRAGVPAGWTVADKTGAGDYGSVNDIAVIWPPGRAPIVLAVYLTQ +PGKDDKLRPEIHGEVARVAIEAf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A4Y5UM98_PSEAI +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLRNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Verrucomicrobium spinosum TaxID=2736 RepID=UPI000492C51E +-----SKLEGVEGSSGARLGVYALDLESGMEV-SRRTEERFPVCSTFKVMLTAAILKQSV +QDAGLMTRRVSYAKEDLVTYSPVTEKHVEGGMTVEALCAAAMQYSDNTAANLLMKILGGP +GAVTAYARSIGDTQFRLDRWETELNTALPGDPRDTSNPAAMGHSLQKLALGDGLPEAQRA +KLVEWLQGNTTGDKRIRAAVPPGWKVGDKTGSGDYGTANDIAILWPPGRKPIVLAIYHTQ +KAADAKWQNEVVAAAARVVLEAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=D9IQH0_ECOLX +-nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTLGELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA +QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGGYGTTNDIAVIWPEGRAPLVLVTYFTQ +SEPKAESRRDVLAAAARIVTDGy +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A0E3XAI9_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTNQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=15 Tax=Bacteria TaxID=2 RepID=D2I9G2_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A0P0H9J6_PROMI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8KQ59_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=A0A4Y5ZMM5_9ENTR +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQQA +QLVTWMKGNTTGAASIQAGLPASRVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A286SCJ4_ACIBA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKRw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=UPI000E69F2B3 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGAALIKHw +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=I6VD99_ACIBA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q844X1_KLEOX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SS60_9BACT +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWVIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Cobetia sp. UCD-24C TaxID=1716176 RepID=A0A0N8HJC7_9GAMM +-----SAIQDIESEVGARIGVTVLDTADGTRF-SWRGNERFPMSSTFKVLACGHLLSRVD +EGQESLSRKVAIRPADLVTYSPITENHTQDGLTLEALCHATITTSDNTAGNLILDTLGGP +AALTAYLRRLDDDSTRLDRRETALNEATPGDPRDTTTPHAMAATLQRLLVGDALSEPSRL +ALQGWMLANTTGDDKLRAALPDDWQIADKTGGGGYGTNNDVAILWPPLRAPLIVAVYLTE +SEAELAARNAAIADVGRLLVK-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2I8ANK3_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTIPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=M5B5Q1_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAVTMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia plantarii TaxID=41899 RepID=A0A0B6S782_9BURK +-----RQLAALDGSFDGRIGVAALDTGSGARL-LHRADERFAFCSTFKTILVSAVLTRAA +GDPRLLSSVIRYRAQDLVRYSPVSEKHVDTGMSVAGLCAAALQYSDNSAANLLIRMVGGP +AAVTAYARSIGDRRFRLDRIETELNDAVPGDERDTTTPAAMLDTLRRVTLGDALDASSRA +RLISWMLGNTTGDARIRAGVPAGWRVADKTGSGDYGSANDVAVIYPPRRAPIVLVVYTTR +DRKDAEYDNAAIASAARIVTAAf +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E353152 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSSGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=J9YNF9_ECOLX +--ETVVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +GQATMDERNRQIAEIGASLIKHw +>[subseq from] Class A beta-lactamase FONA-2 n=2 Tax=Serratia fonticola TaxID=47917 RepID=Q9RIR2_SERFO +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDPRDTSSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTTWIVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] BETA-LACTAMASE TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0000112089 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAAERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium guangdongense TaxID=1325090 RepID=A0A410V6N9_9BRAD +-----EALKQLESKSGGRLGVSVLDTTTGIPI-HHKGDERFPMCSTFKVLAAAAILKDVG +SKLEGLERRVRIEQADLVASSPVTSKHVGGDMTLRELCDAAITMSDNTAGNALLKNIGGP +AGLTSFARSLGDDITRLDRTETELNEATPDDPRDTTTPNAMAANYRRLLLGDVLPPEGRD +QLGKWLIANKTGDTRLRAGLPQGWRVGDKTGAGEHGTCNDVAIVWPRERSPLIIAVYLTG +ATLDPNGRNDVIASVGREVGKAf +>[subseq from] Beta-lactamase class A n=1 Tax=Burkholderia sp. yr520 TaxID=1761779 RepID=A0A329D8P7_9BURK +---AASRLKALEDASNGRLGVSALNTADGARI-DYRADERFPFCSTFKVVLSSAILTRSA +RDEGLLARRIRYAQSDIIANSPVTSKHVADGMTVGELCAAALQYSDNAAANLLIRLLGEP +ADVTAYARSIGDTEFRLDRMETELNTAIPGDPRDTTTPAAMALTLQRLALGNALGVAQRD +QLQAWMRANTTGDKRIRAGVPRDWQVADKTGTGDYGTSNDIAVLWPPARPPIVLVIYFTQ +REQDAKARDDVLASAAKIVAEKf +>[subseq from] Beta-lactamase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A4Q5Q991_9GAMM +-dLLTQRLAELEKKLGGRLGVFILDTQTGKHW-AQRANERFPMCSTFKLIACGAVLAKVD +AGKEDLNRRVYFEKNDLVANSPITEKHAGSEMTFAEICEAAITRSDNTAANIILKSLNGP +SAVTAFARTLGDSVSQLDRYETELNEATPGDIRDTTSPSAMAGNVNKLLLGNTLTIKSRE +QLKTWLVANKTGDAKLRAGLPKEWIVGDKTGAGSYGTTNDVAIIWPTNRKPIITSIYITE +PKVSFDECNAAFAEIGRAITA-- +>[subseq from] class A beta-lactamase n=1 Tax=Duganella radicis TaxID=551988 RepID=UPI0012D738B0 +-------LARLEKESGGRLGVAALNTADGRQL-LHRADERFPFCSTFKMMLSAALLAREP +---ALLKKRIAVDKSDLVPHAPITSKHVGEGMTVAELCEATLQYSDNPAANLLMKQIGGP +AAVTAYARSIGDNEFRLERWETELNTALPGDTRDTTTPLAMAKSLQKLVLGDALPSPARK +QLKDWMLGNTTGATRIRAGVPSGWPVADKTGAGDYGTVNDIAVIWPPGKAPIVLAVYLTQ +PGKDDKLRPEIHGEAARIVIEAf +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007DDA6C2 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAILSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A565FB41_KLEPN +--ETLVKVKDAEDQLGAQVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SED family class A beta-lactamase n=1 Tax=Citrobacter sedlakii TaxID=67826 RepID=UPI0005A60EA7 +-qQVQKKLAALEKQSGGRLGVALINTADNSQV-LYRADERFAMCSTSKVMTAAAVLKQSE +THDGILQQKMTIKKADLTNWNPVTEKYVGNTMTLAELSAATLQYSDNTAMNKLLAHLGGP +GNVTAFARSIGDTTFRLDRKEPELNTAIPDDERDTTSPLAMAKSLRKLTLGDALAGPQRA +QLVDWLKGNTTGGQSIRAGLPARWVVGDKTGAGDYGTTNDIAVIWPEDRAPLVLVTYFTQ +PRQDAKWRKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=X5JYP1_ENTCL +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVMYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=A0A173GQ32_9ENTR +-nDIQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKDLLSQRVEIKSSDLINYNPIAEKHVNGTMTLGELSAAALQYSDNTAMNKLIAHLGGP +GKVTAFARVIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGNALGDTQRA +QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLVLVTYFTQ +PKPKAESRRDVLAAAARIVTDGy +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0B4UAY9_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERSRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9AEY6_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTDELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium vignae TaxID=1549949 RepID=A0A4Q0R5M8_9BRAD +--ALIEAIKQLELKSGGRLGVSVLDTATGVPI-HYRGDERFPMCSTFKVLAAAAILKDAG +SRPERLERRVRIEQADIVENSPITREHVGGEMTLRELCDAAITRSDNTAGNALLKNIGGP +AGLTNFARSLGDILTRLDRTETELNEAAPGDPRDTTTPNAMAANFRRLLLGDVLLPEGRD +QLGKWLIANKTGDTRLRAGLPQSWRVGDKTGAGEHGTTNDVAIVWPPEHSPLIIAVYLTG +ASLDSGGRNDVIASVGRAVAKGf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A346ARK8_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDCWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase class A/beta-lactamase class A CTX-M n=1 Tax=Rahnella sp. BIGb0236 TaxID=2485117 RepID=A0A4R7GN14_9GAMM +--SVQQQLAALEKDSGGRLGVMLINTADNSQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLTRRISLKKSDLVNYNPITEKHLDTGMTIGELAAAALQYSDNTAMNKLIEQLGGP +QKVTAYARTLGDNTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHATLGTALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWIVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PEKDAKSRRDVLASAAKIVTQGy +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2A6EA8 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLAQVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Meiothermus ruber TaxID=277 RepID=UPI0001922F8F +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRLIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Kluyvera georgiana TaxID=73098 RepID=B3LE91_9ENTR +-nDIQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKDLLSQRVEIKSSDLINYNPIAEKHVNGTMTLGELSAAALQYSDNTAMNKLIAHLGGP +GKVTAFARVIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGNALGDTQRA +QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLVLVTYFTQ +PEPKAESRRDVLAAAARIVTDGy +>[subseq from] class A beta-lactamase n=1 Tax=Rahnella sp. RFA10(1/100) TaxID=2511202 RepID=UPI00101F0650 +--SVQQQLAALEKDSGGRLGVMLINTEDNSQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLNRHVSIKKSDLVNYNPIAEKHLGTGMTIGELAAAALQYSDNTAMNKLIGQLGGP +QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVALGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPENKAPLILITYFTQ +PEKNAKSRRDVLASAAKIVTQGy +>[subseq from] Beta-lactamase TEM n=17 Tax=cellular organisms TaxID=131567 RepID=A0A0F8NV65_METMZ +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium jicamae TaxID=280332 RepID=A0A0R3LP72_9BRAD +-qRLIDEIKRLERESGGRLGVCVLDTATGARH-VHRGDERFPMCSTFKALAAAAILARVD +AGKEQLTRRVTFEASALVTYSPVTEKHAGRDMTLAEICEAAVTLSDNTAGNLQLASIGGP +SGLTSFARSLGDQITRLDRDEPSLNEALPDDPRDTTTPNAMASNLQALVVGTALSAPSRE +QLTAWLVANKTGDTRLRAGLPKDWRVGDKTGTGARGTNNDVAVIWPPGKAPIVITGYLTG +ATVPAAQQNAIWASVARAVS--- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudacidovorax sp. RU35E TaxID=1907403 RepID=A0A1N6RYZ4_9BURK +--EAHAALQALDDRFDGRLGVFALDTGSGATL-GHRGGERFPMCSSFKAVLAASMLARSS +RQPDWLAHRVRYAKADLVSYSPVTERHVGEGMTVAELCAATVQYSDNGAANLLMAQSGGP +QALTAFARSQGDSTFRLDRIEPALNSAIPGDERDTTTPEAMARLLQRLVLGEGLPPQERQ +QLADWLRGNTTGARRIRAGMPAAWTVGDKTGTGAHGSASDIGIVWRPGAAPLALAIYTTR +PAADAPADEAVIAEAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A0C5C5N5_PROMI +-nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAVAAVLKQSE +TQKGLLSQRVEIKPSDLVNYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA +QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGGYGTTNDIAVIWPEGRAPLVLVTYFTQ +SEPKAESRRDVLAAAARIVTDGy +>[subseq from] Beta-lactamase n=3 Tax=Escherichia coli TaxID=562 RepID=Q8GA85_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSSGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2DBC17 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSSGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] inhibitor-resistant class A broad-spectrum beta-lactamase TEM-31 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00042DA861 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSCGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Photorhabdus luminescens TaxID=29488 RepID=UPI0006203D3B +--SLHKQLTELENSTKGRLGVALINTANGQEI-QYRGDERFPFCSTFKLILAAAVLHKSM +SQPELLAKHIHYRESDLLSYAPIARKNLNQGMSVAQLCAATVQYSDNTAANLLIKELGGL +EAVNRFTQGIGDPAFRLDRREPDLNSAIPGDLRDTTTPAAMAASVRKIVLGEVLGASQRE +QLIVWLKGNTTGDASIRAGTPADWVVGDKTGGGDYGTTNDVAVLWPPKGAPVVLAVYFTQ +PQQDAESRRDVLAAATRLVMAH- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia TaxID=629 RepID=UPI000FFB086C +-eSLDKQLAELERKSNGLLGIAMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHIKYHESDLLSYAPITRKNLAQGMSVSELCAATIQYSDNTAANLLIKELGGI +AAVNEFARSIGDHTFRLDRLEPDLNTALPNDPRDTTTPAAMAASLNKLVLGDALPAAQRE +QLAIWLKGNTTGGETIRAGAPADWIVGDKTGGGDYGTTNDIAVLWPPTGAPIILVIYFTQ +REKDAKPRRDVLAEATKMVLSH- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0002CA84F9 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMGTTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. FT9W TaxID=2692178 RepID=UPI00136D7DEE +-------LARLEKESGGRLGVAALNTADGRLV-LHRADERFPFCSTFKMMLSAAILAREP +---SLLKKRIQYEKSDLVPHSPITGKRLAEGMTVAELCEATLQISDNAAANLLMKQIGGP +AAVTAYARSIGDTEFRLERWETELNTAIPGDVRDTTTPLAMAKSLQKLVLGDALPAAQRK +QLKDWMLGNPTGATRIRAGVPSGWPVADKTGAGDYGTVNDIAVIWPPGKAPIVLAVYLTQ +PNKDDKSRPDIHGEVAKVVIEAf +>[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. TW-1 TaxID=2717319 RepID=UPI00141FAC03 +---ATRALADLERRAGGRLGVAAWRHGGAPVL-AWRGDERFPFCSTAKVMVAGAVLARAT +REPGLLDERVRYRAADLVAWSPVTEKHVDEGMTIAGLCAAALQASDNSACNLLLDRIGGP +AAVTAFARRIGDTAFRLDRRETALNTAIPGDPRDTTTPRAMARSLQALLLEEALAPEARR +RLLDWMLGNTTGKERIEAGVPAGWRVADKTGTGSYGTTNDVGIVFPPQGASIVVAIYYAG +ATPDAHSDSKVVADAAAIVAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=UPI0009B8C160 +-qRLQQEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRGD +RGESSLDQQIRFEAKDILANSPVTKEHVASGMTLAELCEAAITRSDNTAGNMILREIGGP +AGLTGFFRTIGDNVSRLDRWELALNEGVSGDPRDTTSPVAMLKNLQRVVLGNVLQTVSRQ +KLADWMVANKTGDARLRAGVPRDWRVADKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMEKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. ORS 3257 TaxID=167468 RepID=A0A2U3Q2U2_9BRAD +--ALIEAIKQLELKSGGRLGVSVLDTATGVPI-HYRGDERFPMCSTFKVLAAAAILKDAG +SRPERLERRVRIEQADIVENSPITREHVGGEMTLRELCDAAITRSDNTAGNALLKNIGGP +AGLTSFARSLGDILTRLDRTETELNEAAPGDPRDTTTPNAMAANFRRLLLGDVLLPEGRD +QLGKWLIANKTGDTRLRAGLPQSWRVGDKTGAGEHGTTNDVAIVWPPEHSPLIIAVYLTG +ASLDSGGRNDVIASVGRAVAKGf +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00102E861F +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q93GI3_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=G1FK69_SALER +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Cupriavidus pinatubonensis TaxID=248026 RepID=Q470Y4_CUPPJ +--DAESRLATLERSAGGRLGVFARHTGDSRQV-RHRAEERFPFCSTFKVILAGAVLQRSA +GAPGLLDEHVRYTRQDLVAYSPITEKHVADGMTIAQLCAAAIQYSDNGAANLLMHRLGGP +AAVTGFARSIGDQTFRLDRWETELNTAIPGDPRDTSTPAAMAASLQALALDGALPPVQRN +QLQAWLRGNTTGAARIQAGMPAGWQIGDKTGSGDYGTTNDIAVLWPLAGAPIVVAIYFTQ +AAPDAKWSNETIASAARIAL--- +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=R4NFA1_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDFVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Serratia fonticola AU-P3(3) TaxID=1332070 RepID=U2M054_SERFO +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPMAMAKSLQNLTLGKALAEPQRA +QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Collimonas pratensis TaxID=279113 RepID=A0A127Q7C5_9BURK +-----EQLRQIEAKSGGRLGVAIFDSHSGQTY-AYRGGERFPMCSTFKLLASAFVLKRVD +QGKEQLTRRIRYQKADLVPYSPVTEHHTGAGMTVAELCEAAITQSDNTAANLLLHSFGGP +AQLTAYMRASGDKMTRLDRIEPHLNEAAPGDPRDTTTPSAMVSSLREILLGGNLSGTSRQ +QLTDWLLVNKTGDKRLRALLPSGWRVADKTGTGDQGTANDIGMLLSPDGAPLLVASYLTG +TPGPAAARDAVHAQVGRLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Collimonas fungivorans TaxID=158899 RepID=A0A127P9K0_9BURK +--------RQIEAKSGGRLGVAILDTASGQSH-AYRGDELFPMCSTFKLLAAGLTLHRVD +QAQEQLARRIRYETAELVPYSPATEKHAGGDMSVAELCEATLTLSDNTAANLLLHSFGGP +TQLTAYLRSLGDKVTRLDRIEPDLNQATPGDPRDTTSPSAMLSTMQQLLLGNALSADSRK +QLATWLLANKTGDKRLRALLPAGWRVADKTGSGAYGSTNDIGMLLPPGRAPLLVAAYLTG +TKASEATRNATLAEVGRLAA--- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX85_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVEDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI0007CCDF69 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVEDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Rhodopseudomonas palustris (strain BisB18) TaxID=316056 RepID=Q214B0_RHOPB +--ALAASFAKIEATSGGRLGVAVLDTKSAALV-GYRLDERFPMCSTFKLIAAAAILARVD +AGTERLDRRLRIAPEDILSYAPTTKQHVGKDLSVAELCEAAIVLSDNTAANLLLTRLGGP +AALTRYARSLGDEATRLDRMEPDLNEATPGDPRDTTTPAAMARAVQAVAVGTALSPGSRD +RLITWLIDCKTGGARLRAGLPSSWRVGDKTGSGSHGSSNDVAVIWPQDRAPLIIAAYLTE +TAGSDDQRNATHASVARSIA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A3G2M3D8_9BACT +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q0GMA4_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEEHFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B40419E +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLAGGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] CTX-M type extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q6J8G6_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCCTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGKTTGAASIQAGLPASWVVGDKTGSGDYGTTNDTAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Enhydrobacter sp. CC-CFT640 TaxID=2586908 RepID=A0A5C8PFG6_9PROT +--TLADTFKKIEADSGGRLGVAVLDTQTGTSA-GHRADELFAMCSSFKMLAAAAVLARVD +AGKEKLDRRVPVQASDIIPYSPAVKERVGGTMSLAELCAATVTLSDNAAANLILATFGGP +AAVTAFVRSIGDGVTRLDRTEPTLNEARADDPRDTTSPAAMAATIQKLVLGTALSAASRE +QLTAWLVGNKTGDARLRAGVPRDWRVGDKTGTCNSNTANDVGLAWPPGRQPVIMSVYLTG +ATVNADRQNAAIASVARAVAT-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007D6D2D9 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase FONA-5 n=1 Tax=Serratia fonticola TaxID=47917 RepID=Q9RIQ8_SERFO +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPQAMAISLQNLTLGKALAEPQRA +QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=4 Tax=Gammaproteobacteria TaxID=1236 RepID=A9J5X3_HAEPA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q9FAA2_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDCWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F68E8ED +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTRQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000EF9DE41 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGVRGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007DD62F5 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGVSLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Blastochloris tepida TaxID=2233851 RepID=UPI0013EF2297 +--SLAAQLAGLERAHGGRLGVAILDTGSGRAA-AHRGDERFALCSTFKLLAAGLVLARVD +RGEERLDRRIAYDAAALVPYSPITGPHAGEGLTVGALCEAAVTLSDNTAANLLLDSFGGP +AALTAYLRSLGDAATRLDRREPALNEATPGDARDTTTPLAMLQTLRTLVLGEALSDPSRA +QLAAWLRANRTGDKRLRAGVPKNWQVGDKTGSGGHAATNDVGILWPPGGPPILVAAYYAE +SPAIEDARAAVLAEVGRLA---- +>[subseq from] class A extended-spectrum beta-lactamase TEM-5 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00042D5403 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Duganella sp. OV458 TaxID=1855290 RepID=A0A1G7US83_9BURK +-------LARLEKESGGRLGVAALNTADGRQI-LHRADERFPLYSTFKMMLAAAVLSREP +---ALTKKRIQYDKGDLVPHSPVTGKHVADGMTVAELCEATLQYSDNAAANLLMKQIGGP +AAVTAYARSIGDNEFRLDRWETELNTALPGDVRDTTTPLAMALSLQKLVLGESLPTSQRR +QLKDWMIGNTTGATRIRAGVPAGWTVADKTGAGDYGTVNDIAVIWPAGKAPIVLAVYLTQ +PNKDDKYRAEIHGEVAKVVIEAf +>[subseq from] Beta-lactamase n=1 Tax=Blastochloris tepida TaxID=2233851 RepID=A0A348G1S1_9RHIZ +--SLAAQLAGLERAHGGRLGVAILDTGSGRAA-AHRGDERFALCSTFKLLAAGLVLARVD +RGEERLDRRIAYDAAALVPYSPITGPHAGEGLTVGALCEAAVTLSDNTAANLLLDSFGGP +AALTAYLRSLGDAATRLDRREPALNEATPGDARDTTTPLAMLQTLRTLVLGEALSDPSRA +QLAAWLRANRTGDKRLRAGVPKNWQVGDKTGSGGHAATNDVGILWPPGGPPILVAAYYAE +SPAIEDARAAVLAEVGRLA---- +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum sp. SJZ099 TaxID=2572916 RepID=UPI0011A69C0D +----VQQMAKLESGVNGRLGVFILDTAKGRQW-GYRADERFPMCSTFKFLASAAVLKRVD +QGEERLERRIVYTKESLVPYSPATGKHTGGNLSMSQLCEAAMTLSDNTAANLMLESLGGP +AGLTAFIRSLGDDLTRLDRNEPTLNESLPGDPRDTTTPAAMVADLRKIVLGNALNPASRT +LITQWLLDNQTGAKRVRAGLPTGWKVGDKTGTGSHGSTNTVGVAWTPQGVPLLFAVYLTE +TGADEAQRNGLHAAIGKLIAA-- +>[subseq from] Beta-lactamase SFO-1 n=1 Tax=Citrobacter freundii TaxID=546 RepID=A0A3G1NHF3_CITFR +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVIAVSALLKQSE +MDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAELSAAAIQYSDNTAMNKILEHLGGP +AKVTEYARTIGDKTFRLDRTEPTLNTAIPSDKRDTTSPLAMAKSLQTLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX91_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2MJV7_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00141A51A4 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=A0A345N859_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=H2ERK9_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007E8FEBC +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7HZR6_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8RNX7_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=68 Tax=Bacteria TaxID=2 RepID=Q7X575_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010354915 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013748C39 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX83_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007E8F9B7 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Duganella sp. GV023 TaxID=2135490 RepID=A0A3D9JT79_9BURK +-------LARLEKESGGRLGVAAFNTADGRQL-LHRADERFPLCSTFKMMLAAAVLARDP +---SLLEKRIRYEKSDLVPHSPVTGKHVAEGMTVEALCEATLQYSDNTAANLLMKQIGGP +AAVTAYARSIGDSEFRLDRWETELNSAIPGDVRDTTTPQAMAKSLQKLVMGEALPLHCRR +QLKDWMIGNTTGATRIRAGVPAGWIVADKTGAGDYGTVNDIAVIWPPGRPPMLLAVYVTL +PGKDDKARVELHGEVAKVAIEAf +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00080289D7 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTH5_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=UPI0003608796 +--NAQAQLAALESSVGGRLGLAAFDTASGARV-QHRATERFPMCSTFKMMASAAILARSS +REPGLLEQRVSYARSDILPNSPITEKNLGQGMAVSALCAATIQYSDNAAANLLMKILGGP +SAVTEFARSIGDAVFRLDRWETELNSAIPGDPRDTTSPEAMAASLQRLVLGDGLGAAQRS +QLAAWLLGNTTGATRIRAGVPADWKVGDKTGAGSYGTVNDIAVLWPPAGAPLVMAVYLTF +PQPDAPGRNDVIASAARIAAD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=S4TWB0_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0007DCEA2F +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTMG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E9AE1F +--SLDKQLAALEHSANGRLGIAMINTANGTKI-LYRGAQRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDASIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATKIILS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I2W1_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVGDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010ABBBC7 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEARPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A081M7B9_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A140G9J4_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVL----------- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderiaceae TaxID=119060 RepID=A0A242M2Z2_9BURK +--KISKRLARIEASTSGRLGVSVLDTGSGAHA-GLRADEAFPMCSTFKFLAAGFVLARVD +KGEEDLRRKIVYSKSDLVDYSPVTQHHADSALSVAALCEAAITLSDNTAANLLLASFGGP +AALTAFVRTLGDTQTRLDRNEPTLNESTPGDPRDTTTPNAMLANMRTLLLTDRLSVSSCA +QLRDWLIANKTGAKRIREKLPKDWRVGDKTGTGSHGSTNDIAIIWPPKRAPLLVTAYLTQ +TSAQTARREAAIADIGGLVVSSf +>[subseq from] Class A beta-lactamase n=1 Tax=Yersinia massiliensis TaxID=419257 RepID=A0A2R4NWH8_9GAMM +haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAASALLKKSE +TQKGLMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNAAMNLILTQLGGP +AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA +QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ +PVKDAQNRREILAEAAKIAVSPf +>[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. GDM18 TaxID=2545469 RepID=A0A4R1C7B6_9GAMM +-----SAIQDIESEVGARIGVTVLDTADGTRF-SWRGNERFPMSSTFKVLACGHLLSRVD +EGQESLSRKVAIRPADLVTYSPITENHTQDGLTLEALCHATITTSDNTAGNLILDTLGGP +AALTAYLRRLDDDSTRLDRRETALNEATPGDPRDTTTPHAMAATLQRLLVGDALSEPSRL +ALQGWMLANTTGDDKLRAALPDDWQIADKTGGGGYGTNNDVAILWPPLRAPLIVAVYLTE +SEAELAARNAAIADVGRLLVK-- +>[subseq from] Beta-lactamase n=1 Tax=Marinobacter shengliensis TaxID=1389223 RepID=A0A2T1KNZ8_9ALTE +hnSLIKTVEKVADDLEARVGFAACDLESGQRW-EYHADQRFAMSSTFKTLACAALLHRVD +AGQENLAKKVNVSESDLVTYSPITEKHAGGEMTLSDLCEATLTTSDNTAANLVLRELGGP +EAVTSFARHLGDDVTRLDRWETELNEALPGDNRDTTTPNAMVRNLQTLLLGDALSEPSRE +QLRDWLKGNQVADGLFRAAVPEGWTVADRTGAGGFGSRSITAVIWPPERQPIIVALYLTQ +TEASFEERNAAIAEIGKAIV--- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2B2D13 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARNTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVEDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=4 Tax=Gammaproteobacteria TaxID=1236 RepID=S5FWH2_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=3 Tax=Gammaproteobacteria TaxID=1236 RepID=Q2XPR0_PSEAI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8KRH0_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Epibacterium mobile TaxID=379347 RepID=UPI00080739CC +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPGAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E1FEE9D +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E3482D +--SLDKQLAALEHSANGRLGIAMINTANGTKI-LYRGAQRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATKIILS-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001110E054 +-----EQIKQSENQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A097A289_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVFIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=D9Z4Z4_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=root TaxID=1 RepID=Q8GHI3_PROMI +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSCGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=G9FYZ8_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNNERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus funiculus TaxID=137993 RepID=UPI00101D5BA7 +--ATSRKFVQLEKKFDARLGVYAIDTGTNRTV-AYRPDERFAYTSTFKALAAAVVLQQNS +--IDKLDEVITYTKDDLVTYSPITEKHVDTGMTLREICDAAIRYSDNTAGNLLMQKLGGP +NGFEKALRQIGDNVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPNDKRT +ILTDWMRGNTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPNRDPIIIAILSTH +DTKNATYNNELIAKAAKIALNVf +>[subseq from] Beta-lactamase L2 n=5 Tax=unclassified Bosea TaxID=2653178 RepID=A0A653PVI7_9BRAD +--KVREALFALDRKHGGRLGVAILDSSNGRIV-AHRGEERFAMCSTFKLVAAAFALARVD +RGEEELERRVSYSKADLITYSPVTEKHVEKGLTIAEICDAAVTLSDNTAGNLLLDSFGGP +QGLTDYMRSLGDEASRLDRREPDLNEAKTGDPRDTTTPVAMAGVLRQIVLGGALSPASRQ +QLTTWLVANKTGDKRLRAGVPKGWRIGEKTGTGNNNATNDVGVIWPPGRAPLVVTAYYAE +SSAAFPEREAVLAEVGRLA---- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q933Z8_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKLw +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. th.b2 TaxID=172088 RepID=UPI000A06DF7E +--RLQQEFARVELATSGRLGVAALDMETGLRA-SQRGDERFPMCSTFKALASAAVLHRVD +RGESSLDQRVQIEAKDILANSPVTKEHVASGMTLAEICEAAITRSDNTAGNMILREIGGP +AGLTSFFRTIGDNVSRLDRWELALNEGVSGDPRDTTSPVAMLKNLQRVVIGDVLQATSRQ +RLIAWMVANKTGDARLRAGVPRDWRVGDKSGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMDKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax paradoxus (strain S110) TaxID=543728 RepID=C5CR04_VARPS +--SAEAQLAALERSVGGRLGLAAFDTATGARV-QHRATERFPMCSTFKMMASAAILARSS +REPGLLEQRVSYARSDILPNSPITEKNLGQGMAVSALCAATIQYSDNAAANLLMKILGGP +SAVTEFARSIGDAVFRLDRWETELNSAIPGDPRDTTSPEAMAASLQRLVLGDGLAAAQRS +QLEAWLLGNTTGATRIRAGVPADWKVGDKTGAGSYGTVNDIGVLWPPAGAPLVMAVYLTF +PTPDAPGRNDVIASAARIASD-- +>[subseq from] Beta-lactamase n=2 Tax=Serratia fonticola TaxID=47917 RepID=BLAC_SERFO +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPQAMAISLQNLTLGKALAEPQRA +QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI0005E40979 +-eSLDKQLAELERKSNGLLGIAMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHIKYHESDLLSYAPITRKNLAQGMSVSELCAATIQYSDNTAANLLIKELGGI +AAVNEFARSIGDHTFRLDRLEPDLNTALPNDPRDTTTPAAMAASLNKLVLGDALPAAQRE +QLAIWLKGNTTGGETIRAGAPADWIVGDKTGGGDYGTTNDIAVLWPPTGAPIILVIYFTQ +REKDAKVRRDVLAEATKMVLSH- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. MUM 13 TaxID=1678001 RepID=A0A1S2RAA5_9BACI +-aAAGRKFKQLEKKFDARLGVYAIDTGTNRTV-VYRPDERFAYASTYKALAAGLVLQQNS +--IDKLDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAANLLLQKLGGP +NGFEKALRKIGDNVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPNDKRK +ILTDWMRGNTTGDELIRAAVPKGWEVGDKTGSGDYGTRNDIAIVWPPNRDPIVITILSTR +DTKNATYNNELIAKAAKVALNTf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I616_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLaAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. PAMC 28687 TaxID=1795874 RepID=UPI000784351A +--KISKRLARIEASTSGRLGVSVLDTGSGAHA-GLRADEAFPMCSTFKFLAAGFVLARVD +KGEEDLKRKIVYSKSDLVDYSPVTQHHADSALSVAALCDAAITLSDNTAANLLLASFGGP +AALTAFVRTLGDTQTRLDRNEPTLNESTPGDPRDTTTPNAMLANMRTLLLTDRLSVSSCA +QLRDWLIANKTGAKRIREKLPKDWRVGDKTGTGSHGSTNDIAIIWPPKRAPLLVTAYLTQ +TSAQTARREAAIADIGGLVVSSf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3LUK7_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Providencia stuartii TaxID=588 RepID=V5LEG1_PROST +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVENSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RN76_9BACT +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEKLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q4F7H1_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLPDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSHGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00128DECD7 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNDTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A075MBC8_ECOLX +--ETLVKVKDAEDQLGARVGYIEMDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase CTX-M-4 n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=BLC4_SALTM +-nSVQQQLEALEKSSGGRLGVAQINTADNSQI-LYVADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIRASDLVNYNPIAEKHVNGTMTLAELGAGALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNSAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGMPKSWGVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS018417 TaxID=2033491 RepID=A0A2A8S968_9BACI +--ATSRKFVQLEKKFDARLGVYAIDTGTNRTV-AYRPDERFAYTSTFKALAAGAVLQQNS +--IDKLDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLQKLGGP +NGFEKALRQIGDNVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLSNDKRT +ILTDWMRGNLTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPNRDPIIIAILSTH +DTKNATYNNELIAQAAKVALNAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1L7B4G6_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERDRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A224A9L1_SHISO +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKH- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=K4Q514_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMISTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTL8_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSAHSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=Q46029_CITKO +--QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE +TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT +SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA +QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGAGDYGTTNDIAVIWPEDRAPLILVTYFTQ +PQQDAKGRKDILAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. 6(2017) TaxID=1197460 RepID=UPI0013E0F6B7 +--RLQQEFARVELATSGRLGVAALDMETGLRA-SQRGDERFPMCSTFKALASAAVLHRVD +RGESSLDQRVQIEAKDILANSPVTKEHVASGMTLAEICEAAITRSDNTAGNMILREIGGP +AGLTSFFRTIGDNVSRLDRWELALNEGVSGDPRDTTSPVAMLKNLQRVVIGDVLQATSRQ +RLIAWMVANKTGDARLRAGVPRDWRVGDKSGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMDKCNEVIANVARAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0E3JSK4_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERDRQIAEIGASLIKHw +>[subseq from] SFO family class A extended-spectrum beta-lactamase n=1 Tax=Serratia sp. 14-2641 TaxID=1841657 RepID=A0A1C7W9S8_9GAMM +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRADERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTLGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTTWGVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0U3S9M4_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKH- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI00044975E3 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMXTTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00081BEFE9 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAVLIEHw +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI000BE34AE8 +--AIHQKLTALEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDTTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGTGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B409F9A +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLASVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=8 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q79JA5_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Proteus mirabilis TaxID=584 RepID=I6ZQ49_PROMI +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNIGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium nanningense TaxID=1325118 RepID=A0A4Q0RZJ8_9BRAD +---LFDAVQQLEIKSGGRIGVAVLDTKTGASV-HHKGDERFPMCSTFKVLASAAILKGAG +DKLDRLDRRIRIEQADIVENSPVTREHVGPDMSLRELCEAAMTRSDNTAGNLLLKNMGGT +AGLTAFARSLGDNVTRLDRTETELNEAAPGDPRDTTTPNAMAENFRRLLFGNELMPESRD +QLAKWLIANKTGDKRLRAGLPQNWRVGDKTGAGEHGTTNDVAVVWPPLRSPLIIAVYLTG +ASLDMNGQNEVIASAGREVAREf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q4F7H2_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLMRSALPAGWFIADKSGAGERGSHGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL93_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKH- +>[subseq from] class A beta-lactamase n=1 Tax=Nevskia soli TaxID=418856 RepID=UPI0004A7104E +-----ARFAAIEKRVAGRLGVAALDTASGRRI-GHRAAERFPLCSTFKFLAVAAVLKRVD +EGRENLDRRIGYSQGDLLEYAPITRQHEKEGMTVSALCAAAIEYSDNTAANLLLQSLGGP +SAIGRYAATLGDGVTRLDRTEPSLNEAVPGDPRDTTSPAAMVGDLRAILLGKALSPASLQ +NIQTWLVANTTGGSRLRAGLPADWRVGDKTGTGGHGATNDIAILWPPGREPILVAAYLTE +TAAPAAERNRALAEVGRIIAGSf +>[subseq from] Beta-lactamase FONA-4 n=3 Tax=Serratia fonticola TaxID=47917 RepID=Q9RIR0_SERFO +--NIQQQLSELEKSSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDERDTSSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTTWIVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=Q9RIR3_SERFO +--NIQQQLSELEKSSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDERDTSSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTTWIVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D5CE58_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. FT134W TaxID=2692171 RepID=UPI00136DD812 +-------LARLEMESGGRLGVAAFNTADGRQL-LHRADERFPLCSTFKMMLAAAVLARDP +---SLLEKRIRYEKSDLVPHSPVTGKHVADGMTVEALCEATLQYSDNTAANLLMKQIGGP +AAVTAYARSIGDSEFRLDRWETELNSAIPGDVRDTTTPQAMAKSLQKLVMGEALPLHCRR +QLKDWMIGNTTGAARIRAGVPAGWVVADKTGAGDYGTVNDIAVIWPPGRPPILLAVYVTL +PGKDDKARVELHGEVAKVAIEAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Neisseria gonorrhoeae TaxID=485 RepID=A0A1W5T935_NEIGO +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPATMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Collimonas pratensis TaxID=279113 RepID=A0A127R1V8_9BURK +-----EQLRQIEAKSGGRLGVAIFDSHSGQTY-AYRGGERFPMCSTFKLLASAFVLKRVD +QGKEQLTRRIRYQKADLVPYSPVTEHRTGAGMTVAELCEAAITQSDNTAANLLLHSFGGP +AQLTAYMRASGDKMTRLDRIEPHLNEAAPGDPRDTTTPSAMVSSLREILLGGNLSGTSRQ +QLTDWLLANKTGDKRLRALLPSGWRVADKTGTGDQGTANDIGMLLSPDGAPLLVASYLTG +APGPAAARDAVHAQVGRLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2P9DUS6_ECOLX +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A3FFR8_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVALCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Class A beta-lactamase TEM-238 n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5S9EDG4_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMISTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRREPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella huaxiensis TaxID=2153354 RepID=UPI000DD30D38 +--AIQRKLTDLEKSSGGRLGVALINTTDNSQI-LYRGDERFAMCSTGKVMAAAAVLKQSE +VDNQVLNKRLEIKKSDLVVWSPVTEKHLQSGMTLAELSAATLQYSDNTAMNKMIGYLGGP +DKVTAFARSIGDVTFRLDRTEPALNTAIPGDERDTTTPLAMAEILHKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPAGWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella aerogenes TaxID=548 RepID=Q6PP89_KLEAE +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase class A n=1 Tax=Paraburkholderia sartisoli TaxID=83784 RepID=A0A1H4HJU3_9BURK +----EAKLAALETSMAGRLGVAALNTANGATL-MHRADERFAFCSTCKVMIVSAILTRSA +KEPGFLQQRVRYTKADLVAYSPVTEQHVAEGMTIGELCAAGIDYSDNTSANLLIRIVGGP +AAVTAFARSIGDDTFRLDRWETELNTAIPDDPRDTTTPAAMLASVQRLALGDALGAPQRN +QLQAWMRANTTGGERIRAGVPAGWDVIDKTGTGDYGATNDVAVIWPPAKPPVVLVTYLSQ +RDRDAKSRSDVLAAAARIVVAAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q9R2G5_ECOLX +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGVGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium cajani TaxID=1928661 RepID=UPI0012F8699B +--RLLDAIKQLEIRSGGRLGVAVLDTRTGASI-HHKGDERFPMCSTFKALASAAILKGAG +DKLDRLDRRIRIEQADIVENSPVTREHVGSDMSLRELCEAAMTRSDNTAANLLLKNMGGP +AGLTAFARSLGDKVTRLDRTETQLNEAAPGDPRDTTSPNAMAGNFRRLLFGNELMPEARD +QLAKWLIANKTGDYRLRAGLPQNWRVGDKTGAGGNGTNNDVAVVWPPQRSPLIIAVYLTG +ASLDMNGQNEVIASAGREVAREf +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0011F3AC38 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGPRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1S6KJQ2_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSVLPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] inhibitor-resistant class A broad-spectrum beta-lactamase TEM-37 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00042D3DC6 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMISTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERDRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0G3IAZ6_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALLEHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007DDFF40 +--ETLVKVKDAEDQLGERVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus rhizosphaerae TaxID=297318 RepID=A0A1R1E524_9BACL +------------EEHGVGVSVDIEDLSGHETI-ELGSRDAYYSASIIKLALIATLMQEVD +AGQHSLDEMLTVKPEDVVGGAGSLQNKFPQEVTIGRLAKLMITQSDNTATNVLIGLV-GF +DKVNAFIKSQGFTVTHLGRKMMTPAKS--PAEDNYTSAPEMLTLLDRIYNAKVVSAKSRE +QILEWMKAQEV-NTKFGAVLQ-GKPIAHKTGELGD-VSHDVGYFLIPGR-EIAIAVLTKV +LKKAQELDNPYVQRIAKATYNY- +>[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus rhizosphaerae TaxID=297318 RepID=A0A1R1E524_9BACL +-------------REGIRVSVGIKDLSGSAEV-LLGSLQSYMPASTIKMALVSTLMQQVD +KGTLTLDQKVTVEPDDVVGGTGSLQKETPQDVTIERLARLMITQSDNTATNVLIDVV-GL +DKVQALMDQLGLKTMHLGRKMFAAA--PTPEQDNYIDAADLVTLLAKIYNHEFLSAQSSE +QIIHWMKAQEV-NTKFGAALP-DAPIAHKTGENAN-VTHDVGYFLVPGK-EIAISVMTEV +TTEAQTIGNPVVQSVAKAVYS-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q46954_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. NFR16 TaxID=1566248 RepID=A0A1H7BZX5_9PSED +--SLEQRLAALERRHGGRLGVAIFDTASERMI-SHRGDERFALCSTFKCLAVACVLARVD +RQQEDLSRLLVYGKEQLVPYSPTTEKHADGSLSVGSVCEAAITLSDNTAANLLLDSLGGP +QALTAWLRTIGDPATRLDRREPELNENRPGDLQDTTTPHAMLQTLNRLVLGDILSPASRD +QLIAWLVNNKTGDDKLRAGLPEGWRVGDKTGSNARNASNDVAVIWPPRRPPIIVTVYCSD +ARGSSDQLDALIADVGRLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=G1FTI5_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A5GXS5_KLEPN +--ETLVKVKDAEDKLGARVGYIEMDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=D2K8A9_ELIME +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLICGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3P5G766_ECOLX +--------KDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1B3B5U5_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAEIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Stella vacuolata TaxID=217070 RepID=UPI001152F881 +--ATQARLADLEARHGGRLGVSVLDTGSGQRI-EHRANERFAMCSTFKLLAASMVLSRVD +RAEERLDRRIRFTAADVVDYSPVTGPRAGGPMTMGEVCEAAMTQSDNTAGNLMLQSFGGP +AALTAYARSLGDPVTRLDRMETALNEAAPGDPRDTTTPAAMVDNLAQLALGPALSEPSRA +QLITWMVGNRTGDRRLRAGFPEGWRVGDKTGTGGHGSAADIAVVWRPERTPLVVAVYCAE +ATAPPERRNSLFEEVARVIA--- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F6670D0 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPARMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Citrobacter rodentium TaxID=67825 RepID=A0A482PIC7_CITRO +-qQVQQKLAALEKQSGGRLGVALINTADNSQL-LYRGDERFAMCSTSKVMVAAAVLKQSE +TRPAILQQKIPIKKADLTNWNPVTEKYVGKEMTLAELSAATLQYSDNTAMNKLIAHLGGP +GKVTAFARSTGDTTFRLDRQEPELNTAIPGDERDTSSPRAMADSLRNLTLGDALADTQRA +QLVAWLKGNTTGGQSIRAGVPAHWVVGDKTGAGEYGTTNDIAIIWPENRPPLILVTYFTQ +RQQDAKWRKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum lipoferum (strain 4B) TaxID=862719 RepID=G7ZBA1_AZOL4 +---LAERLAVLEERTGGRLGVAMLDTGSGRLQ-GWRVDERFPMCSTFKFLLAAAVLKGVD +QGRERLDRRIPVTSADLVPYAPFAETRLNGTPTVAELCEAAMTLSDNVAANLLLPGVGDP +AGLTAFLRGIGDKTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMERLLLGDVLRPDSRR +QLSDWMIANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAILWPENRPPLLVASYLTQ +TAKEFKQHDSIHAEVARAVA--- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00096BC36E +-----EQIKQSESQLSGRVGMIEMDLTSGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A1YTM7_PROMI +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZI96_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKRSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=A0A0E3UVG0_ECOLX +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=A0A0G4Q215_PROVU +--TIEEQLTTLEKNSQGRLGVALINTKDNSQV-TYRGDERFAMASTSKVMAVAAVLKESE +KQSGLLDNPITIKKTDLVPYSPITEKHLATGMTLAQLSVATLQYSDNTAMNKILDYLGGP +SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEQNAKYRKDIIAKAAEIVTKEf +>[subseq from] class A extended-spectrum beta-lactamase TEM-6 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000016F27B +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=V5N0A6_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKADRIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0014122B53 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRGEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Streptococcus pneumoniae TaxID=1313 RepID=Q6SQJ9_STREE +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAIATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. PS24 TaxID=2609961 RepID=UPI00140CAC78 +----SALFETLEGTAGGRLGVCAWNTADGRRI-LYRAEERFPFCSTFKVILAGAILAHSA +RVDGFLQRQVHYTKNDLVTYSPVTEKHLTDGLTVAELCAAALQYSDNTASNLLMKLLGGP +EAVTTFARSIGDRDFRLDRWETALNSALPGDPRDTTSPVAMAQSLHALALGDSLAVAQRE +QLQAWLRGNTTGAKRIRAGVPTDWQVGDKTGTGDYGTTNDVAVIWPSAGGPIVLAVYYTQ +LAADAKPRDDVIAAATRIVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9L8E2_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q2V9Y4_PSEAI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3HUP1_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=C9DT08_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000DC7BF0C +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTAQRLSARSQQ +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli (strain B / BL21-DE3) TaxID=469008 RepID=UPI000181CC64 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRSEERFPMMSTFKVLLCGAILSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KGLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTPASRQ +QLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIVAALGPDGKPSRIVVIYTTG +SQATMDELNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. FJAT-42376 TaxID=2014076 RepID=A0A3G6UU07_9BACI +--ATRQKFGQLEKQFDARLGVYAIDTGTNRTV-VYRPDERFAYASTFKALAAGVLLKQNP +--IDSLDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAANLLLQKLGGP +NGFEKGLREIGDHVTEADRFETDLNTAIPGDIRDTSTARALATSLKAFTVDGVLPNEKRA +ILTDWMRRNTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAVIWPPNRDPIIIAILSTR +DTKDATYDNELIAKAAKVALNAf +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=Q06DP4_ENTCL +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQSDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=Q9S679_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSLGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q0GMA6_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIDEIGASLIKHw +>[subseq from] Beta-lactamase n=6 Tax=Bacteria TaxID=2 RepID=A0A3Q8AXR7_ACIBA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRVVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Yersinia enterocolitica TaxID=630 RepID=Q58G58_YEREN +--SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATKIILS-- +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0002E6CCBB +--SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATKIILS-- +>[subseq from] Beta-lactamase (Fragment) n=4 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A649UII2_ECOLX +-------LAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKI----- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=E7AXL5_ECOLX +-nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA +QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGGYGTTNDIAVIWPEGRAPLVLVTYFTQ +SEPKAESRRDVLAAAARIVTDGy +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI001249FB31 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SFO family class A extended-spectrum beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=A0A292AHS8_SERFO +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRADERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPITWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Massilia phosphatilytica TaxID=2026176 RepID=A0A2S8H9V9_9BURK +-----DAFADLERRAGGRLGVAAWRRGGGPVL-AWRGDERFPFCSTAKVMVAATVLARES +REPGLLDERVRYKKADLVSWSPVTEQYIDDGMTVAGLCAAALQHSDNSACNLLLDRIGGP +AAVTAFARRIGDTAFRLDRRETELNAALPGDARDTTTPRAMAHSLEALLVDEALAPDARR +RLLDWMLANTTGKERIQAGVPAGWRVADKTGTGAYGTTNDVGIVFPPQGQPVIVAIYYTQ +SAPDAQSDSKVVADAAAIVAQ-- +>[subseq from] BETA-LACTAMASE n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0000110CCD +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERDRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia heleia TaxID=634127 RepID=UPI0005AB4CA6 +--SLEKQLAAIEAQAGGRLGVAMLDTANGHVR-GWRMQERFPMCSTFKVLLASAVLTRKD +HGKEDLARKIVYSPAQVVSYSPVSGPRAGSEMTVAELCEAALTRSDNTAANLLLESIGGP +SAITAFARSIGDPVTRLDRNETTLNDAIPGDPRDTTTPAAMVANLRELLLGERLSSASRE +QLIAWLVANKTGDARLRAGLPKDWRVGDKTGTGDHGTANDVAIVWPTGRAPILVTAYLTG +AAASSAQRDAAIAQVGAVVA--- +>[subseq from] Uncharacterized protein (Fragment) n=4 Tax=marine sediment metagenome TaxID=412755 RepID=X1GP87_9ZZZZ +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Thalassospira lucentensis TaxID=168935 RepID=UPI000DED4AD7 +--DIVQTVRDLEGRLDARIGIAVMDTQNNQNW-HYRGDERFPMTSTFKALACAAILSRVD +EGKENLERKVVFAKSDLVTYSPVTEKHVGAPMTIGALCDATMSLSDNTAGNLILDALGGP +DGVTAFLRDIGDNTTRLDRREPELNEAVPGDLRDTTTPDAIARTLRDLVLGDVLSDPSRQ +HLKSWLVGNKVGGPLIRAGMPDDWVIGDRTGAGGYGSRGNIGIIWPTGRKPLVVAVYITQ +TDASFDARNAAIAEIGNAIA--- +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=Q58G80_ECOLX +-nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA +QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLVLVTYFTQ +SEPKAESRRDVLAAAARIVTDGy +>[subseq from] class A beta-lactamase n=1 Tax=Erwinia toletana TaxID=92490 RepID=UPI00034C8963 +-eTLAQQLRALEKSANGRLGVALIDSGSLREL-HYRSDERFAMASTFKALLAAAMLQQSV +KQPDLLKKRINYKQSDLVTYSPVTEKNLKQGMTIAELCAAAIELSDNAAANLLLREIGGP +QAITRLARESGDMKTRLDRWEPLLNSAIPGDARDTTTPRAMASNLQQLALGQALPAARQQ +LLITWLKQSQTGAESIRAGVPQGWVVGDKTGAGAYGTTNDVAIIWPPKGKPLILAIYFTQ +KHQHAEARRDVLASATRLVLAEw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1Y6M3H9_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMEDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Yersinia hibernica TaxID=2339259 RepID=A0A481QBP2_9GAMM +---VGKQLAELERTANGRLGIAMINTANDHKI-QYRGTQRFPFCSTFKFMLAAAVLGQSQ +SQPNLLDKHIHYHESDLLSYAPITRKNLAHGMTVSQLCAATVQYSDNTAANLLIKELGGL +AAVNQFARDIGDQMFRLDRQEPDLNTALPNDPRDTTTPAAMAASLQKLVLGDALLPAQRQ +QLATWLTGNTTGDATIRAGAPKDWMVGDKTGSGDYGTTNDIAVLWPPEGAPVVLVVYFTQ +REKDAQPRHDVLASATKILLSQf +>[subseq from] TEM-94 ES-beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00062CAFBF +--ETLVKVKDAEDQLGGRVGYIELDLASGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTAASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium phaseoli Brasil 5 TaxID=526949 RepID=A0A1W6GFA6_9RHIZ +--NIERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFTLARVD +KGDESLDRRVTYGKEKLVDYSPISEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEDIKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +KLIAWLVASTTGKERLRAGLPADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAD +ATAPMKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=H7CHH5_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQAIMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A3FFR4_ACIBA +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDARVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella aerogenes TaxID=548 RepID=Q1KY81_KLEAE +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGVRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A4S2I2N0_ACIBA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI0014330057 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFCTTWGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007DD01B6 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRLIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI000BF1D70A +--AIQQKLANLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SHPDVLNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=H6D9D5_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEPLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase TEM-12 n=5 Tax=Enterobacteriaceae TaxID=543 RepID=BLAT_KLEOX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9S678_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Streptomyces sp. CB02400 TaxID=1703944 RepID=UPI00093FD87A +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSKNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005DF661A +--SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGARRFPLCSTFKFMLAAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATKIILS-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Bacteria TaxID=2 RepID=UPI000D1E9889 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8L1Y1_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLGRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=A0A370FP56_9BURK +--EAQAALKALDEGFDGRLGVFALDTGSGATL-SHRAGERFPMCSSFKAVLAASMLDRSR +RQPDWLSHRVRYAKADLVSYSPVTERHVGEGMTVAELCAATVQYSDNGAANLLMAQSGGP +QALTAFARSQGDDSFRLDRIEPALNSAIPGDERDTTTPEAMARLLQRLVVGEGLPPRERQ +QLGDWLRGNTTGARRIRAGVPAAWTVGDKTGTGAHGSASDIGVVWRPGRAPLTLAIYTTR +PKADAPADEAVIAEAARIVA--- +>[subseq from] Beta-lactamase n=3 Tax=Enterobacterales TaxID=91347 RepID=D3VY77_ECOLX +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. PBL-E5 TaxID=434014 RepID=UPI00131863FA +--DLPAQLAEIERGSGGRLGVGVLDTATGQRA-GHREDERFPMCSTFKLLASALVLARVD +RHEERLERRVVFGARDLVDGSPITGQHAGGNMTMAELCEAAITRSDNTAGNMLLASFGGP +KVFTTYARSLGDTLTRLDRNETSLNEARPGDPRDTTTPAAMLGNLQKILVGDALSPSSRA +QLLRWLDANKTGDERMRARLPAGWKVGDKTGSGERGATNDIGILRPPGRAPILVTIYLTE +TEAPANARNATIASAGAAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Thalassospira sp. TaxID=1912094 RepID=A0A2E9W9V9_9PROT +--DIVQTVRDLEGRLDARIGIAVMDTQSNQNW-HYRGDERFPMTSTFKALACAAILSRVD +EGKENLERKVVFAKSDLVTYSPVTEKHVGAPMTIGALCDATMSLSDNTAGNLIMDALGGP +DGVTAFLRDIGDNTTRLDRREPELNEAVPGDLRDTTTPDAIARTLRDLVLGDVLSDPSRQ +HLKSWLVGNKVGGPLIRAGMPDDWVIGDRTGAGGYGSRGNIGIIWPTGRKPLVVAVYITQ +TDASFDARNAAIAEIGNAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q93A80_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAVTMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A127S9W4_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERYRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YPK7_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMVVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007DD3696 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVESSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI0006BA0FF2 +--ETLVKVKDAEDQLGARVGYIELDLISGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=D0ES28_PROMI +-nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAVAAVLKQSE +TQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQSLRNLTLGNALGDTQRA +QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLVLVTYFTQ +SEPKAESRRDVLAAAARIVTDGy +>[subseq from] class A beta-lactamase n=1 Tax=Reyranella massiliensis TaxID=445220 RepID=UPI0002D26626 +--DATPRFADLERRNGGRLGVAAFDSASGRRI-GHRSEERFPMCSTFKFLAAAFVLARVD +RGEERLDRRIVYSTQDLVTYSPVTKDHVGPALSVAELCDATMTLSDNTAGNLLLASFGGP +AGLTAYARSLGDQTTRLDRIETALNEGLPGDPRDTTSPVAMLGTMHRLLLGDALSAASRE +RLTGWLVANKTGDKRLRAGMP-GWKVGDKTGTGGNGSANDIAIVWPTGRAPLLVTVYYTG +STISDEARNEVIAEAGRIVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6ALB2_ECOLX +-----VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKH- +>[subseq from] Beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=D5LY09_SERMA +--ETLVKVKDAEEQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM-1 BETA-LACTAMASE n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0000111743 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWNPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX89_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +TGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=A0A4Y5ZN65_9ENTR +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFFAQHGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000F62A9D0 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=bacterium 2013Ark19i TaxID=1561004 RepID=UPI000B80AB1B +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00124A5D22 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=UPI0007846F3E +--KAEAQLAALERSVGGRLGLAAFDTATGARV-QHRATERFPMCSTFKMMVSAAILARSS +REPGLLERRVSYARSDILPNSPITEKNLGQGMAVSALCAATIQYSDNAAANLLMKILGGP +PAVTEFARSIGDAVFRLDRWETELNSAIPGDPRDTTSPEAMAASLQRLVLGDGLAAAQRS +QLEAWLLGNTTGATRIRAGVPADWKVGDKTGAGSYGTVNDIGVLWPPAGAPLVMAVYLTF +PTPDAPGRNDVIASAARIASD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9R771_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=O53043_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Francisella philomiragia TaxID=28110 RepID=A0A0U3EBL2_9GAMM +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. SJZ130 TaxID=2572918 RepID=A0A542MJK4_9BURK +----VQQMAKLESGVNGRLGVFILDTAKGRQW-GYRADERFPMCSTFKFLASAAVLKRID +QGEERLERRIVYTKESLVPYSPTTGKHTGGNLSMSQLCEAAMTLSDNTAANLMLESLGGP +AGLTAFIRSLGDDLTRLDRNEPTLNESLPGDPRDTTTPAAMVADLRKIVLGNALNPASRT +LITQWLLDNQTGAKRVRAGLPTGWKVGDKTGTGSHGSTNTVGVAWTPQGVPLLFAVYLTE +TGADEAQRNGLHAAIGKLIAA-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTM7_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMSVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus pacificus TaxID=2026187 RepID=A0A3P1B1Y1_9BACI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Phyllobacterium sp. YR620 TaxID=1881066 RepID=A0A1H0V405_9RHIZ +--DLDAAFKGLEEKTGARLGVAALDTASDSKI-EYRAHERFAMCSTFKFLAAAAVLAKVD +RKEEKLDRVIKYGKGDLVAGSPATGKHVDEGMTLAALCEAAITLSDNTAGNLLLDNLGGP +KGLTQYARSLGDATFRLDRRETELNEATPGDPRDTITPAHILKDLQKTVLGNALSKSSRD +QLIEWLLANKTGDKRLRGGLPKGWSVGDKTGTSDSGMANDIAVIWPPSRKPILLAVYLYD +PKGTADSRNEIHRKVASLVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Thalassospira lucentensis MCCC 1A00383 = DSM 14000 TaxID=1123365 RepID=A0A367VXU7_9PROT +--DIVQTVRDLEGRLDARIGIAVMDTQNNQNW-HYRGDERFPMTSTFKALACAAILSRVD +EGKENLERKVVFAKSDLVTYSPVTEKHVGAPMTIGALCDATMSLSDNTAGNLILDALGGP +DGVTAFLRDIGDNTTRLDRREPELNEAVPGDLRDTTTPDAIARTLRDLVLGDVLSDPSRQ +HLKSWLVGNKVGGPLIRAGMPDDWVIGDRTGAGGYGSRGNIGIIWPTGRKPLVVAVYITQ +TDASFDARNAAIAEIGNAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacteraceae bacterium TaxID=1909293 RepID=A0A354UWI0_9PROT +--TFARKLAGIEGAIAGRLGVAVREIGTGRHY-GYRADERFPLCSTFKVLACAAVLKRVD +GGQEDLNRRIRFGPGDLVTYSPVTKDHVGGDMTLGALCTAAMTQSDNTAGNLILASLGGP +GAVTAFARSIGDQVTRLDRTEPDLNTAIPGDPHDTTTPGAMAADLGRLVTEGCLSRNSRH +QLVTWLISNQTGGAKLRAGVPAGWRVGDKTGGGAWGTTNDVAVIWPPPRDPFVVCVYLTE +TKASFDARNATIAAVGRAVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q8RSU6_KLEOX +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZM14_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGATSIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q937J3_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGA +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=3 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5UCV1_9BACT +--DAATRIAAIEARIGGRIGVAALDTGNSKHV-EHRADERFPMCSTFKFLAAAAVLKRVD +EKKEKLERFVPYGAKEILEYAPVTKEHLKDGMTLGALCAAAIEQSDNTAGNLLLNAIGGP +AGLTNFVRTLGDRVTRLDRIEPELNSAIPGDERDTTTPAAICSDMQRLLLGDALSEASRR +QLEDWLQRNETGGPMIRAGIPKNWVLGDKTGRGSNGATNDIAILRPPDRAPILLAIYFIG +STTPAKDREAAIAEVAKIVAESf +>[subseq from] Beta-lactamase n=3 Tax=Klebsiella TaxID=570 RepID=A0A2S1LUN0_KLEOX +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=163 Tax=root TaxID=1 RepID=Q79DR3_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=Q8RPY9_ENTCL +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAVTMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERDRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium icense TaxID=1274631 RepID=A0A1B1UST1_9BRAD +-qRLIDEIKRLERESGGRLGVCVLDTATDARH-VHRGDERFPMCSTFKMLAAAAILAQVD +AGKEQLTRRITFDASALIVYSPVTEKRVGGDMTLAEICEAAVTLSDNTAGNLLLASIDGP +PGLTAFARSLGDQVTRLDRNEPSLNEALPDDPRDTTTPNAMASNLQALILGTALSAASRE +QLTAWLVANKTGDTRLRAGLAKDWRVGDKTGTGARGTNNDVAVIWPPGKAPIVITAYLTG +ATVSAAQQNATLASVARAVS--- +>[subseq from] class A extended-spectrum beta-lactamase TEM-16 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000016F836 +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Chimaeribacter coloradensis TaxID=2060068 RepID=A0A2N5E5S9_9GAMM +--TLAARLADLEHSANGRLGVTLIDTGNQQAI-SYRGDKRFAMASTFKVLLAGAVLQRSV +AQPGLLEKRIRYDRAVLQSYSPVTGKHLDDGMTIAELCAAAIEWSDNTAANLLLTELGGP +QTITRLARSLHDDKTRLDRWEPELNTAIPGDERDSSTPQAMAHNLQKLALGDALPPAQQQ +QLIAWLKGSQTGAKTIRAGVPAGWEVGDKTGSGEYGTTNDLAIIWPPHGKPLVLALYFTQ +QKADAQARRDVLATATRWVLK-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3LUL1_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVLLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas sp. SF2003 TaxID=2136172 RepID=UPI000D1BF112 +-----SAIQDIESEVGARIGVTVLDTADGTRF-SWRGNERFPMSSTFKVLACGHLLSRVD +EGHESLSRKVAIRPADLVTYSPITENHTQDGLTLEALCHATITTSDNTAGNLILDTLGGP +AALTAYLRRLDDDSTRLDRRETALNEATPGDPRDTTTPHAMAATLQRLLVGDALSEPSRL +ALQGWMLANTTGDDKLRAALPDDWQIADKTGGGGYGTNNDVAILWPPLRAPLIVAVYLTE +SEAELAARNAAIADVGRLLVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=Q0GMA5_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMAVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000A07E20A +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0C7AUD6_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Undibacterium parvum TaxID=401471 RepID=A0A3Q9BPK5_9BURK +----RKKLRALEQSFDGRLGLFAINTANGMSI-GLRESERFPLCSTFKMMLAAAVLDKSR +QSAGLLEQVITYTEKDLLDYSPVTEQHLADGMTVAQLCAATVNFSDNAAANLLMKLLGGP +AVVTAFARSIGDQSFRLDRWEPDLNSAIPGDLRDTTTPEAMAVSLQRLTLGDALPKAERE +QLQTWLRASTTGASRIKAGLPADWQSGDKTGTGSYGTAHDIAVIWPPNRAPVVLAIYTKQ +HKKNANGRSDIVAAAAKIVS--- +>[subseq from] Extended spectrum beta-lactamase CTX-M n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZD2_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCITSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLALAAKIVTN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Duganella sp. CY42W TaxID=2692169 RepID=A0A6B1IXA8_9BURK +-------LARLEKESGGRLGVAAFNTADGRQL-LHRADERFPLCSTFKMMLAAAVLARDP +---SLLEKRIRYEKSDLVPHSPVTGKRVAEGMTVEALCEATLQYSDNTAANLLMKQIGGP +AAVTAYARSIGDSEFRLDRWETELNSAIPGDVRDTTTPQAMAKSLQKLVMGEALPLHCRR +QLKDWMIGNTTGATRIRAGVPAGWIVADKTGAGDYGTVNDIAVIWPPGRPPILLAVYVTL +PGKDDKARVELHGEVAKVAIEAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q93K43_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Proteobacteria TaxID=1224 RepID=UPI000011F58A +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSLRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLATIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGSLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A0M3E4G9_VIBPH +--QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE +TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT +SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA +QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ +PQQDAKGRKDILAAAAKIVTE-- +>[subseq from] SED family class A beta-lactamase n=1 Tax=Citrobacter amalonaticus TaxID=35703 RepID=UPI0007334E3E +--QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE +TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT +SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA +QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ +PQQDAKGRKDILAAAAKIVTE-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Bifidobacterium dentium TaxID=1689 RepID=UPI000C1C47A7 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A120HUS0_ACIBA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001071D71D +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Borrelia coriaceae Co53 TaxID=1313292 RepID=W5SXK0_9SPIR +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Caballeronia udeis TaxID=1232866 RepID=UPI001060BF04 +----QDQLKQLESSAGGRLGVAALNTADGKQV-NYRADERFPLCSTFKLMLVSAVLEQSE +SQKGLLERRIHYARSELLSWAPITKKQIATGMTVAELCAAALQYSDNTAANLLMKLVGGP +ETVTAYARSIGDNQFHLDRWEPDLNSAIPGDPRDTSTPAAMARSLQRVTLGDALGTSQRS +QLQTWLLGNTTGAGKIAAALPAHWMIGDKTGSGDYGTTNDIGVIWPAGKPPIVLAIYLTQ +REQDAKARDDVVASAARIVVGAf +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI00094B8D3E +--SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGAQRFPFCSTFKFMLAAAVLDQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLIKELGGS +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAVMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATKIVLAH- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. 18069 TaxID=2681415 RepID=UPI00135783DB +--RFQQAVHQIEIDSGGRLGVAVLDTHSGLAY-AHRGMERFPMCSTFKFLAAALVLARVD +QGQEQLTRRIAVQASDIVPHAPATQPRVGGLMTMAELCDAAVTLSDNPAANLLLQSFGGP +QALTAYARSLGDDFTRLDRIEPDLNEALPGDPRDTTTPEAMLQTLRKIVLGDALSPTSRA +QIVRWLQDNKTGDRKLRAQLPAGWRVGDKTGGGGYGTNNDIGVLWPPGRAPILVSSYLTQ +TTADQATRDRALAQVGRLAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YPN5_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] class A beta-lactamase n=1 Tax=Desulfovibrio alcoholivorans TaxID=81406 RepID=UPI0004973D7A +-kALHAQLAALSREAGGRLGVAFLDPATGRRF-AFRGGERFPFCSTFKLVLVAAVLRKSQ +DEPGLLAQQVAYGQGDLLAWAPATRKALEQGMTVGELCAAAITVSDNTAANLLLDRIGGP +RALTAYARSLGDTAFRLDRREPELNTAVPGDPRDTTTPAAMARTVEKLVLGDALAAPQRR +QLADWLKGNTTGGESIRAGVPAGWTVGDKTGSGAYGTTNDVAVLWPPQGGPVVLAVYYTQ +PRKDAPARKDVLAAATRLVL--- +>[subseq from] Beta-lactamase class A n=3 Tax=Burkholderiales TaxID=80840 RepID=A0A4R1P271_9BURK +----QDQLKQLESSVGGRLGVAALNTADGKQV-NYRADERFPLCSTFKLMLVSAVLEQSE +SQKGLLERRIHYARSELLSWAPITKKQIATGMTVAELCAAALQYSDNTAANLLMKLVGGP +ETVTAYARSIGDNQFHLDRWEPDLNSAIPGDPRDTSTPAAMARSLQRVTLGDALGTSQRS +QLQTWLLGNTTGAGKIAAALPAHWMIGDKTGSGDYGTTNDIGVIWPAGKPPIVLAIYLTQ +REQDAKARDDVVASAARIVVGAf +>[subseq from] Beta-lactamase n=1 Tax=Thalassospira lucentensis TaxID=168935 RepID=A0A358HR17_9PROT +--NIVQTVRDLEGRLDARIGIAIMDTQSNQNW-HYRGDERFPMTSTFKALACAAILSRVD +QGKENLERKVVFAKSDLVTYSPVTEKHVGAPMTIGALCDATMSLSDNTAGNLIMDALGGP +DGVTAFLRDIGDNTTRLDRREPELNEAVPGDLRDTTTPDAIARTLRDLVLGDVLSDPSRQ +HLKSWLVGNKVGGPLIRAGMPDDWVIGDRTGAGGYGSRGNIGIIWPTGRKPLVVAVYITQ +TDASFDARNAAIAEIGNAIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000F530C32 +--DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAT +GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP +AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA +QLVTWMLGNTTGETRIRAGVPAGWRVADTTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR +PGKDAKYDNATLAAVARIVTATf +>[subseq from] Beta-lactamase n=1 Tax=bacterium A52C2 TaxID=1855383 RepID=A0A1H9K0F3_9BACT +-dALAASFASIEKRLQARLGVAILDTETRRAW-KHRAAERFPLCSTFKLLAAGAVLAKVD +AGDEDPARRIRFGKADVVTYSPVTQHHVGDGMTLAEISAAALTQSDNTAGNLILDSIGGP +EAVTRFARSLGDEVTRLDRRETALNEATPGDPRDTTSPEAMVADLGALLLGPTLSGRSRE +QLAAWMVANETGGAKLRAGLPKDWRVGDKTGGGDHGAMADVAIAWPPNRKPVIAAVYITE +TEASFDDRNAAIAEIGRALA--- +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI0009B6836C +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTK-- +>[subseq from] Beta-lactamase n=3 Tax=Enterobacterales TaxID=91347 RepID=Q9ZFV9_MORMO +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SED family class A beta-lactamase n=1 Tax=Citrobacter amalonaticus TaxID=35703 RepID=A0A6B1TZ46_CITAM +--QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE +TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT +SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA +QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ +PQQDAKGRKDILAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q9RMS4_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSGGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. FT109W TaxID=2692170 RepID=UPI00136D9D31 +-------LARLEMESGGRLGVAALNMADGRQL-LHRADERFPLCSTFKMMLAAAVLARDP +---SLLEKRIRYEKSDLVPHSPVTGKHVADGMTVEALCEATLQYSDNTAANLLMKQIGGP +AAVTAYARSIGDSEFRLDRWETELNSAIPGDVRDTTTPQAMAKSLQKLVMGEALPLHCRR +QLKDWMIGNTTGAARIRAGVPAGWVVADKTGAGDYGTVNDIAVIWPPGRPPILLAVYVTL +PGKDDKARVELHGEVTKVAIEAf +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=A0A0B4U9Z7_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRGEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERDRQIAEIGASLIKHw +>[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus stellifer TaxID=169760 RepID=A0A089LYY6_9BACL +-----------AEEHGVGVSVDIEDLSGHETI-ELGSQDAYYSASIIKLALIATLMQEVD +AGQHTLDETLTVKPEDVVGGAGSLQKKFPQDVTIGRLAKLMITQSDNTATNVLIGLV-GF +DKVNAFIKSQGFTVTHLGRKMMTPAKS--PAEDNYTSAPEMLTLLDRIYNAEVVSAKSRD +QILEWMKAQEV-NTKFGAVLQ-GKPIAHKTGELGD-VSHDVGYFLIPGR-EIAIAVLTKV +LKKAQELDNPYVQRIAKATYNY- +>[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus stellifer TaxID=169760 RepID=A0A089LYY6_9BACL +----------AAEREGIRVSVDIKDLSGGAEV-LLGSRQSYMPASTIKMALVSTLMQQVD +KGALTLGQKVTVEPDDVVGGTGSLQKETPQDVTIERLARLMITQSDNTATNVLIDVV-GL +DKVQALMDQLGLKTMHLGRKMFAAAP--TPAQDNYIDAADLVTLLAKIYNHEFLSTQSSE +QIINWMKAQEV-NTKFGAALP-DAPIAHKTGENAN-VTHDVGYFLVPGK-EVAISVMTEV +TTEAQAIGNPVVQSVAKAVYS-- +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=BLAC_CITKO +--QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE +TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT +SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTCPLAMAKSLHKLTLGDALAGAQRA +QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGAGDYGTTNDIAVIWPEDRAPLILVTYFTQ +PQQDAKGRKDILAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Shigella sonnei TaxID=624 RepID=Q0VTQ9_SHISO +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGRRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas delhiensis TaxID=366289 RepID=A0A239MIR4_9PSED +-----ERLKQLERDSGGRLGVAVLDSGDGRRF-GLREDERFPLCSTFKLLLAAAVLARVD +RGEEQLARRIVYGRGDLVPYSPVSERHVGKPLSIAELCEAAVTLSDNGAANLLLASLGGP +AGLTAWLRGTGDEVSRLDRNEPTLNEALPDDPRDTSTPRAMVATLQRLLLGDVLQSTSRA +QLDAWLAANRTGDKRIRAGLPPLWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG +SPASAEKRDAVLAEVGRLA---- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00128F50F7 +--ETLVKVKDAEDQLGARVGYIELDLNSDKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=4 Tax=root TaxID=1 RepID=D9HTE8_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIVEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q5PSW6_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGSRGIIAALGPDGKPSRIVVIYTTG +GQATMDERNRQIAEIGASLIKHw +>[subseq from] FONA family class A beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=A0A4P8U435_SERFO +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE +TDKNLLAKRMEIIQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPQAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Phyllobacterium myrsinacearum TaxID=28101 RepID=A0A2S9JE22_9RHIZ +---FETAFKDLEKASGARLGVSVHDTGSGKRI-GYREKELFAMCSTFKFFAAAAILSRVD +QKKEKLDRVIRYGKSDLVTYSPVTEKHVADGMTLSAICEAAITWSDNAAGNLMLDALGGS +QGMTDYARSLGDTISRLDRREPELNEAKPGDPRDTTTPAAMRENLEKTVLGTALSEPSRK +QLTDWLVGNKVGDKRLRAGLPKDWKVGDKTGTSDSGMANDVAVIWPPDRKPIVLTVYLYD +PKGTPDSRNLIHQKVARLVADH- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoduganella sp. CY13W TaxID=2692176 RepID=UPI00136E10CB +-------LTRLESDAGGRLGVFALNTADGQHA-QHRADERFPFCSTFKLMLAGAILARGP +---ALLKQRIRYSSSDLVSYSPISGKYAGKGMTVAALCAATLQYSDNTAANLLIQQLGGV +AAVTAFARSIGDQAFRLDRMETQLNTALPGDLRDTTTPAAMAESLNRLVLGDALAPLARK +QLKDWLLGNTTGDTRIRAGVPSGWLVGDKTGTGDYGSTNDIGIIWPPGKAPIVLAVYYTQ +QGKDDKARSEVIAEAARIALAAf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas soli TaxID=1306993 RepID=A0A1H9E6N6_9PSED +---LRKALQQLEATTGSTIGLWALDTGSGQQL-AWRAEERFAFCSTFKAILAGAILHRSQ +AEPGLLERRIAYGAEQLVVYSPVTEKHVGAGMTVAGLCAAAVQYSDNTAGNLLLELVGGP +SGLTAFTRSLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLGDGLAAAERQ +QLQDWLKGNTTGDARIRAGVPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWIVVVFSRG +TKADAPWNSETIAAATRVVVEAw +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas soli TaxID=1306993 RepID=UPI0009E049DD +---LRKALQQLEATTGSTIGLWALDTGSGQQL-AWRAEERFAFCSTFKAILAGAILHRSQ +AEPGLLERRIAYGAEQLVVYSPVTEKHVGAGMTVAGLCAAAVQYSDNTAGNLLLELVGGP +SGLTAFTRSLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLGDGLAAAERQ +QLQDWLKGNTTGDARIRAGVPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWIVVVFSRG +TKADAPWNSETIAAATRVVVEAw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000846A7E5 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGVVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=E5Q900_ECOLX +-----KQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium icense TaxID=1274631 RepID=UPI0009F27367 +-qRLIDEIKRLERESGGRLGVCVLDTATDARH-VHRGDERFPMCSTFKMLAAAAILAQVD +AGKEQLTRRITFDASALIVYSPVTEKRVGGDMTLAEICEAAVTLSDNTAGNLLLASIDGP +PGLTAFARSLGDQVTRLDRNEPSLNEALPDDPRDTTTPNAMASNLQALILGTALSAASRE +QLTAWLVANKTGDTRLRAGLAKDWRVGDKTGTGARGTNNDVAVIWPPGKAPIVITAYLTG +ATVSAAQQNATLASVARAVS--- +>[subseq from] class A beta-lactamase n=1 Tax=Alcanivorax gelatiniphagus TaxID=1194167 RepID=UPI00110D693F +----IDTVKQVENRLQARVGVAISDTDSGRRW-RYQADQRFPFASTFKVLACGALLHKVD +AGEEQLNRRVRYTKDDLVTYSPTTEQHVEDGMTLAALCEATITLSDNTAANLVLNAIDGP +AGLTAFLRGTGDTVTRLDRYETELNEGTPGDLRDTTTPDAMLDTLYTLLFGEVLSADSRR +QLLDWMKADRVADDLLRAGVPDNWTVADKTGAGGHGSRSIIAVMWPPQRGPVLAAIYLTE +ADASMDQRNAAIAEIGKALA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodospirillales bacterium URHD0017 TaxID=1380357 RepID=A0A1H8WN31_9PROT +--DATSRLAELERRNGGRLGVAAIDTASGHRV-DHRAEELFPLCSTFKFLAAALVLTRVD +RGEEKLDRRVVFAEKDLVTYSPVTKEHVTPGMSVAEICDAAVTLSDNTAGNLMLASFGGP +AGLTAYMRSLGDRTTRLDRIETELNEAKPGDPRDTTTPAAMLDTMQRLLIGDALSASSRD +RLIGWLLASKTGGKRLRAGLPADWRVGDKTGGGNNGTANDVAIAFPPGRAPILIAAYYTE +STISDDARNTVIAEAGRLAV--- +>[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica I TaxID=59201 RepID=A0A3Z4SE10_SALET +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDELNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A9QW43_KLEPN +--ETLVKVKDAEDQVGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQTAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. CF313 TaxID=1144315 RepID=J2KK32_9BURK +--SAEAQLAELERASGGRLGVAGFHTGRGARI-QHRAHERFPLCSTFKLMLAAAVLERSA +KDASLLARRIGYGKADLVSWSPITEKHVADGMTVAELCAATVQYSDNAAANLLLKMLGGP +ATVTAFARGIGDQAFRLDRTEPELNTAIPGDLRDTTTPAAMSDSVQRLALGDALGTAQRD +QLTTWLLGNTTSAERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPVVLSVYLTF +PQKDAKGRSDVIASATRIVVA-- +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=Q6QR76_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Mesorhizobium sp. GR13 TaxID=2562308 RepID=UPI0010C0D850 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGVSLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI000D3211A7 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLQNLGDDVTRLDRWEPELNEAITNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8RNX6_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Gammaproteobacteria TaxID=1236 RepID=UPI000929FFE2 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIDASLIKHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B41A5E9 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2WEB9_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q93A79_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDEQNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=bacterium RRLBTPL IV-3 TaxID=342579 RepID=Q3S2X0_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGHSLIKHw +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=Q8KRG9_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGGRGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0008FC96A0 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMETTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. 770b2 TaxID=1566271 RepID=A0A1I5QU73_9BURK +-qEASAQIAALESASGGRLGVVGFNTATGARV-QHRADERFPFCSTFKLMLAAVVLERSA +KEGGLLARRVSYSKGDLVTYSPITEKNIATGMTVAELCAAAVQYSDNTAANLLMKMLGGP +PAVTAFARSSGDDAFRLERWETELNTAIPGDLRDTTTPAAMAASVERLVLGNALGAAQRQ +QLKTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGTTNDVGVLWPPAGAPLVLAVYLTF +PEKDAKGRNDVVASATRIAV--- +>[subseq from] Beta-lactamase n=1 Tax=Duganella sp. BJB475 TaxID=2233914 RepID=A0A3E1RY90_9BURK +----AALLAKLEGESGGRLGVAALNTGDGRRL-LHRADERFPFCSTFKTMLSAAVLTREP +---ALLKKRVRYTKKDLVTYSPVTEKHVGKGMTVAALCEATLQTSDNAAANLLMQQIGGP +AAVTAFARSIGDMEFRLDRIETELNTALPGDPRDTTTPASMAESLHKLLLGDGLGAPQRK +QLKDWMLGNTTGDTRIRAGVPSGSLVADKTGTGDYGSTNDIGVIWQPGKAPIVLVIYLTQ +PGKDDKARSEILAEATRIVVEAf +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013303031 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR +QMLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=P78144_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDEQNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Photorhabdus luminescens TaxID=29488 RepID=A0A2S8Q369_PHOLU +--SLHKQLTELENSTKGRLGVALINTANGQEI-QYRGDERFPFCSTFKLILAAAVLHKSM +SQPELLAKHIHYRESDLLSYAPIARKNLNQGMSVAQLCAATVQYSDNTAANLLIKELGGL +EAVNRFTQGIGDPAFRLDRREPDLNSAIPGDLRDTTTPTAMAASVKKIVLGEVLGASQRE +QLIVWLKGNTTGDASIRAGTPADWVVGDKTGGGDYGTTNDVAVLWPPKGAPVVLAVYFTQ +PQQDAESRRDVLAAATRLVMAH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=V5LVW5_PSEAI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEFSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=A0A4U9D1D7_RAOTE +heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD +AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVVELCAAAITLSDNTAANLLLASVGGP +QGLTAFLRRSGDQTSRLDRWETELNEALPGDVRDTTTPQAMANTLRNLLTGSVLSAASRQ +QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMDERNRQIAEIGETLVKHw +>[subseq from] Beta-lactamase SHV-2 n=13 Tax=Gammaproteobacteria TaxID=1236 RepID=BLA2_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI0009AAC897 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTE9_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIARIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=B5A5T0_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDEQNRQIAEIGASLIKLw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2B4531 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNETLPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1S7BI72_ECOLX +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTNGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGTSLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q5XUL7_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERVVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Marinobacter sp. LQ44 TaxID=1749259 RepID=A0A142FMG0_9ALTE +hnSLIKTVEKVADDLEAHVGFAAYDVESGQRW-EYHADQRFAMSSTFKTPACAALLHRVD +TGQANLSRKVHVSESDLVTYSPITEKHAGGEMTLSDLCEATLTTSDNTAANLVLRELGGP +EAVTSFARHLGDDVTRLDRWETELNEALPGDNRDTTTPNAMVRNLQTLLLGDALSEPSRE +QLRDWLEGNQVADGLFRAAVPEGWTVADRTGAGGFGSRSITAVIWPPERQPIIVALYLTQ +TEASFEERNAAIAEIGKAIV--- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q5H739_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAVPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. RIT623 TaxID=2559075 RepID=A0A4Y8SML0_9PSED +--TVQHQLQQLEHSAGITLGLWALDTGSGKQL-AYRAEQRFAFCSTFKAVLAGAILHRSE +TDSGLLNRRIAYAAEQLVVYSPITEKHVGAGMTVAELCAATLQYSDNTAGNLLLEQVGGP +AGLTAFARQLGDPTFRLDRNEPTLNTALPDDPRDTTTPLAMGVTLQRLLLGDALAPAGRE +QLQAWLKGNTTGDARIRAGVPKGWIVGDKTGSGDYGVANDVGIVWPKGRAPWILVVFSRG +PQQSSPWNHEPIAAATRLVVQAw +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter amalonaticus TaxID=35703 RepID=A0A2S4RYP2_CITAM +--TIKQKLTALEKSSGGRLGVALIDTADDSQL-LYRGDERFAMCSTSKVITAAAVLKQSE +DDKNVLHQKMSIKKSDLTNWNPITEKNVDGEMTLAELSAAALQYSDNTAMNKLIDHLGGT +DNVTAFARSIGDTTFRLDRTEPTLNTAIPGDERDTSTPLAMAKSLRNLTLGNALGATQRA +QLVEWMKGNTTGGKSIRAGLPASWVVGDKTGGGDYGTTNDIAVIWPENHAPLILVTYFTQ +PQQDAKDRKDVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E10279 +--SVDKQLAELERNANGRLGVAMINTGNGTKI-LYRAAQRFPFCSTFKFMLAAAVLDQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMIVSELCAATIQYSDNTAANLLIKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTARPNDPRDTTTPAAMAASMNKLVLGDALRPAQRS +QLAVWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASVTKIILS-- +>[subseq from] Beta-lactamase n=26 Tax=Bacteria TaxID=2 RepID=A0A1B7K3V6_9ENTR +-nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKDLLSQRVEIKSSDLINYNPIAEKHVNGTMTLGELSAAALQYSDNTAMNKLIAHLGGP +GKVTAFARAIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA +QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLVLVTYFTQ +SEPKAESRRDVLAAAARIVTDGy +>[subseq from] Beta-lactamase n=1 Tax=Duganella sp. CF517 TaxID=1881038 RepID=A0A1H8EDL4_9BURK +------RLVRLEAQSGGRLGVAALDTADGRQL-LHRADERFPFCSTFKMMLSAAVLAREP +---SVLQQTIRYDKAELVAHSPITERHLDGGMTIEALCAATIQYSDNTAANLLIRHLGGP +EEVTAYARSIGDRQFRLDRWETALNSAIPGDPRDTTTPAAMMASLHKLTVGEALPPAKRK +ILTDWLIGNTTGATRIRAGVPSNWTVGDKTGAGDYGTINDIAILWPPNKPPIVLAVYLTQ +PGKDDKARAEILGQAAKIVIDAf +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E44BE2 +--SLDKQLAALEHSANGRLGIAMINTANGTKI-LYRGAQRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLVKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDASIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATKIILS-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B9U2I6_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +MPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. CCOS 191 TaxID=1649877 RepID=A0A0F7Y4A0_9PSED +---LRKALQQLEATTGSTIGLWALDTGSGQQL-AWRAEERFAFCSTFKAVLAGAILHRSQ +AEPGLLERRIAYGAEQLVVYSPVTEKHVGAGMTVAGLCAAAVQYSDNTAGNLLLELVGGP +PGLTAFARSLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLGDGLAAAERQ +QLQDWLKGNTTGDARIRAGVPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWIVVVFSRG +AKADAPWNSETIAAATRVVVEAw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=B8XLK1_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERIRQIAEIGASLIKHw +>[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI0004503F16 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Vibrio ishigakensis TaxID=1481914 RepID=A0A0B8P936_9VIBR +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Pigmentiphaga aceris TaxID=1940612 RepID=A0A5C0B028_9BURK +--RFRTEIARIEAASGGRLGVAILDTHDGVFY-GHREDERFPMCSTFKFLLAAHVLARVD +RKEERLDRRVAVRTVDLVAYSPATQPHADGEMSIAALCDASVTLSDNTAANLLLASAGGP +AGLTAYLRQLGDAHTRLDRNEPSLNTARPGDPRDTTTPAAMLGSMRKLVLGDALSPASRT +QLTRWLVDNKTGDARLRAGIPKGWKVGDKTGSGAYGTNNDIGVIWPSGRDPVLVTAYLTG +TVEPVATRERALAEVGKLVT--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=G0Z390_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X7E7_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGGRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKH- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Gammaproteobacteria TaxID=1236 RepID=UPI0002CC593A +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMETTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. M2T2B2 TaxID=682998 RepID=A0A2U9SAX9_9PROT +---LAARMAALEGRTGGRLGVAMLDTGTGRLQ-GWRMDERFPMCSTFKFLLAAAVLKAVD +QGREKLDRRIPVTEADLVPYAPFAETRLNGTPTVAELCEATMTLSDNVAANLLLPGVGNP +AGLTAFLRGIGDGITRLDRNEPTLNSAIPGDPRDTTTPAAMARSMERLMVGEVLRPESRR +QLIDWMIANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAILWPDNRPPLLVASYLTQ +TAKGFKQHDSIHAEVARAVAE-- +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0001BE674B +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELGEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. Pop5 TaxID=1223565 RepID=K0VP01_9RHIZ +-dDIQRRLAALEKRTGGRLGVSVLDTQTSISF-SYRGSEAFPMCSTFKALAAGFVLARVD +KGQESLDRRVTYGKEKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +PALTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPEAMLDTLGNLTLGSILAETSCD +RLIAWLVASTTGKERLRAGLPEDWKVGDKTGTGPNGSLGDIAVIWPPDRSPIVAAVYIAE +ATASAKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Chromobacterium subtsugae TaxID=251747 RepID=UPI000640D036 +--SAAARLSALEADFGGRLGVCALDTASGAEL-GHRAGERFPFCSTFKAMLVGAVLARSA +KQPGLLAERIHYARRDLVEYSPRTEPHLADGMTVAELCAAAVQYSDNSAANFLLKWLGGP +AALTAYMRSIGDESFLLERWEPELNRAVPGEARDTSTPQAMAQSLRRLALGDALAPHAQR +QLVEWLRGNTTGDEKIRAGVPAGWVVGDKTGNGRYGSSNDIAVLWPPGRAPAVLTVFTTQ +AREDAKQRHQVVAAAARIAAD-- +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI00061C4462 +--SLDKQLAALEHSANGRLGIAMINTANGTKI-LYRGAQRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLVKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATKIILS-- +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E1771C +--SLDKQLAALEHSANGRLGIAMINTANGTKI-LYRGAQRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLVKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATKIILS-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A7ISS0_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGANERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Class A beta-lactamase n=1 Tax=Rahnella woolbedingensis TaxID=1510574 RepID=A0A419N222_9GAMM +--SIQQQLTALEKDSGGRLGVMLIDTADNSQI-AYRADERFAMCSTSKFMAASAILKESE +SNKALLDQHVALKKSDLVNYNPITEKHLNDGMTIGELAAAALQYSDNAAMNKLIEHLGGP +HKVTDYARTLGDKTFRLDRTEPTLNTAIPGDDRDTSTPRAMALSLQHATLGSALAETQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPENKAPLVLVTYFTQ +PQKDAKSRRDVLASAAKIVTQGy +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0006581777 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=B6VB30_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSVLPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Cobetia marina TaxID=28258 RepID=UPI0008662192 +-----ANLQEIEQRVGARLGVTVLDTANGRRV-SWRGDERFPMSSTFKVLACGNLLSRVD +ARQESLSRKVEIRPADLVTYSPVTERQVEGDMTLAALCRATITTSDNTAGNLILDAIGGP +VGLTNYLRTLKDDITRLDRRETALNEATPGDPRDTTTPDAMASTLQRLLLGEALSEASRL +TLQGWMLANTTGSDKLRAALPDDWQIADKTGGGGHGTNNDIAIIWPPNHAPLIVAVYLTE +SEAERAVRDAAIADVGRLLVS-- +>[subseq from] Beta-lactamase n=1 Tax=Dokdonella koreensis DS-123 TaxID=1300342 RepID=A0A161HIN5_9GAMM +-----DRLAELERASGGRLGVAVLDTATGRSL-GWRDEERFAMCSTFKFLLAAAVLQRVD +RGELTLDRRLPIRKDDLIHHSPVTERHVGSHLAVADLCEATMTLSDNAAANLLLPLVGGP +AGLTATLRAWGDATTRLDRPEPHLNDVPPGDPRDTTTPREMAAHVQRLVLGDLLQPASRE +RLTGWLAGNRTGDHRLRAGLPKGWRVGDKTGSGP-GTTNDVAIVWPEGRAPFALACYLTG +SSLKDDGRNAILASVAREVAG-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000C0BE023 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYKTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=Q2PXM9_ACIBA +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPDNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=4 Tax=Leminorella grimontii TaxID=82981 RepID=A0A085HAX1_9GAMM +---IQQKLANLEKSAGGRLGVALIDTEDNSRV-LYRGDERFAMCSTSKVMAVAAVLKQSE +TDKGVLSKKIKIKKADLVNWNPITEKHVNSSMTLEELSAATLQYSDNVAMNKIIAHLGGP +NKVTAFARSIDDTTFRLDRTEPSLNTAIPGDERDTTTPLAMAESLRNLTLGNALGETQRA +QLVEWLKGNTTGGESIRAGLPKAWIVGDKTGSGDYGTTNDIAVIWPENRAPLILVTYFTQ +PKQDAKSRRDVLAAAAKIVAE-- +>[subseq from] Beta-lactamase n=2 Tax=Legionella rubrilucens TaxID=458 RepID=A0A0W0XXD6_9GAMM +--SLQQKLAALEASTGGRLGIAAINQANGMTI-QYHARQAFPLCSTSKAMGVAALLSRSM +RDKTLLQEKIHYSKQDLVVHSPETEKHLADGMTLAELCEATITQSDNAAINLILKKMGGP +KAVTAFARSIGDNQFRLDRFEPELNTAIPGDPRDTTTPKAMALSLQKLTTTDTLAAPERQ +LLIKWLRNNTTGGARIRAGLPEGWVVGDKTGTGDYGTTNDIGVIWPPHCQPVTLAVYFTQ +PKVDATPNNDVIAAATRIVISAf +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00101F16F7 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLF--- +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A6XFB8_PROMI +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2U8JH97_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIHTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Phyllobacterium myrsinacearum TaxID=28101 RepID=UPI00102A6AAA +---FETAFKDLEKASGARLGVSVHDTGSGKRI-GYREKELFAMCSTFKFFAAAAILARVD +QKKEKLDRVIRYGKSDLVTYSPVTEKHVADGMTLSAICDAAITWSDNAAGNLMLDALGGS +QGMTDYARSLGDTISRLDRREPELNEAKPGDPRDTTTPAAMRENLEKTVLGTALSEPSRK +QLTDWLVGNKVGDKRLRAGLPKDWKVGDKTGTSDSGMANDVAVIWPPDRKPIVLTVYLYD +PKGTPDSRNLIHQKVARLVADH- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B40503D +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLAIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=B7FDE2_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLAIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Shigella sonnei TaxID=624 RepID=UPI000662E90F +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSPAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q2WEB7_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKYLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella sp. HMSC16A12 TaxID=1581108 RepID=UPI0008A1C68C +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKYLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter sp. CFNIH10 TaxID=1920110 RepID=A0A3Q8DCH8_9ENTR +--QVQEKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE +TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT +SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA +QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ +PQQDAKGRKDILAAAAKIVTE-- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A381G8S3_CITAM +--QVQEKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE +TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT +SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA +QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ +PQQDAKGRKDILAAAAKIVTE-- +>[subseq from] SED family class A beta-lactamase n=1 Tax=Citrobacter sp. MGH 55 TaxID=1439319 RepID=UPI0004A084BA +--QVQEKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE +TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT +SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA +QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ +PQQDAKGRKDILAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium retamae TaxID=1300035 RepID=UPI0007C6D4E4 +---LIDEIRRLERESGGRLGVCVLDTATGARH-VHRGDERFPMCSTFKMLAAAAILARVD +AGKEQLTRRITFDASALIVYSPVTEKRVGGDMTLAEICEAAVTLSDNTAGNLLLAGIGGP +PGLTAFVRSLGDQVTRLDRDEPSLNEALPDDPRDTTTPNAMASNLQALILGKALSAASRE +QLTAWLVANKTGDARLRAGFAKDWRIGDKTGTGARGTNNDVAVIWPPRKAPIVITAYLTG +ATVSAAQQNATLASVARAVS--- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum lipoferum TaxID=193 RepID=A0A5A9GFE3_AZOLI +--AFAARMTELEGRTGGRLGVAVLDSGTGRLH-GWRGDERFPMCSTFKFLLAAAVLKSVD +QGKDRLDRQIPVTKADLVPYAPFSEKRLNGTPTVAELCEAAMTLSDNVAANLLLPGVGNP +AGLTVFLRRIGDRITRLDRNEPTLNTAIPGDPRDTTTPAAMVHSMERLLVGDVLRPDSRR +QLIDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAILWPEGRAPLLVASYLTQ +TAEGFKQQDAIHAEVARAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=U5KKE2_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWGIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKH- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B6FA355 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Proteus TaxID=583 RepID=A0A2J9LCP9_PROMI +-nTIEEQLNTLEKYSQGRLGVALINTKDNSQI-TYRGEERFAMASTSKVMAVAAVLKASE +KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLGGP +AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDNSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEQDAKYRKDIIAKAAEIVTK-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium retamae TaxID=1300035 RepID=A0A0R3MC94_9BRAD +---LIDEIRRLERESGGRLGVCVLDTATGARH-VHRGDERFPMCSTFKMLAAAAILARVD +AGKEQLTRRITFDASALIVYSPVTEKRVGGDMTLAEICEAAVTLSDNTAGNLLLAGIGGP +PGLTAFVRSLGDQVTRLDRDEPSLNEALPDDPRDTTTPNAMASNLQALILGKALSAASRE +QLTAWLVANKTGDARLRAGFAKDWRIGDKTGTGARGTNNDVAVIWPPRKAPIVITAYLTG +ATVSAAQQNATLASVARAVS--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YE83_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKNE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9R746_KLEPN +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGGSERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007D6CD3A +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=W8E5Z0_ECOLX +--ETLVKVKDAEDQLGAPVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=Q8KSA6_ECOLX +-nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAVAAVLKQSE +TQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA +QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGGYGTTNDIAVIWPEGRAPLVLVTYFTQ +SEPKAESRRDVLAAAARIVTDGy +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=U5U781_PSEAI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase class A/beta-lactamase class A CTX-M n=10 Tax=Bacteria TaxID=2 RepID=A0A4R2ZCR7_9GAMM +--SVQQQLTALEKESGGRLGVMLIDTADNSQI-AYRADERFAMCSTSKFMAASAILKESE +VKKNLLTQHVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP +NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWIVGDKTGSGDYGTTNDIAVIWPENKAPLVLVTYFTQ +PEKDAKSRRDVLASAAKIVTQGy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL84_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKH- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=C5IXH9_PROMI +-nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAVAAVLKQSE +TQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA +QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLVLVTYFTQ +SEPKAESRRDVLAAAARIVTDGy +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Bacillus TaxID=185979 RepID=UPI000B891C33 +--ATHREFAQLEKNFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS +--IDKLNEVITYTKDDLVTYSPVTEKHVDTGMTLGEIAEAAIRYSDNTAGNLLFKKLAGP +KGFEKALRQIGDRVTMADRFETELNEAIPGDIRDTSTPKALATDLKAFTVGNALPADKRK +ILTDWMRGNTTGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR +DKKDATYDNELIAQAAKVTIN-- +>[subseq from] TEM family class A beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=UPI0007DDBF91 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLGEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001144B8FD +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=209 Tax=root TaxID=1 RepID=Q7X574_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0003FE868C +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI000797DC5A +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=Q6V3W5_ACIBA +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Gammaproteobacteria TaxID=1236 RepID=UPI000450B0DD +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q6KB04_KLEOX +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001330A9A1 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGNPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella michiganensis TaxID=1134687 RepID=UPI0006E65094 +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=4 Tax=Enterobacterales TaxID=91347 RepID=Q7BP43_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSSGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI001374BC08 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDKRNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=3 Tax=Klebsiella TaxID=570 RepID=A0A0G3SBL4_KLEOX +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=8 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A068F3Z2_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase OXY-1 n=13 Tax=Bacteria TaxID=2 RepID=BLO1_KLEOX +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI00042D3CCF +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASRRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2MJC2_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASRRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007DCF298 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIEGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=3 Tax=Escherichia coli TaxID=562 RepID=Q934D7_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSSGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKLw +>[subseq from] Beta-lactamase n=1 Tax=mixed culture bacterium PE_gF3SD01_32 TaxID=663178 RepID=C8C169_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIDDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Massilia sp. NR 4-1 TaxID=1678028 RepID=A0A0K1JUJ2_9BURK +--TAEAQLAALEKAAGGRLGVAAWRTDSAKRI-GHRSEERFPLCSTFKAMLAAAVLARSA +NDEELLGKSVRYRADELVTYSPVTEKHVDDGMTVAALCAATLQYSDNSAANFLMRMMGGP +QALTAYMRSIGNPVFQLERWETELNTAIPGDTRDTANPASMARSLQALLLGDALPAPQRR +QLDTWMRGNTTGDQRIRAGVPAGWSVADKTGAGAHGTVNDIGIAYPPSGAPIVIAVYYTR +EQKDAPTNQDIIAAATRIVM--- +>[subseq from] class A beta-lactamase n=1 Tax=Cobetia sp. MM1IDA2H-1 TaxID=1268241 RepID=UPI000985AC0E +-----ANLQEIEQRVGARLGVTVLDTADGRRV-SWRGDERFPMSSTFKVLACGNLLSRVD +ARQESLSRKVEIRPADLVSYSPVTERQVEGDMTLAALCRATITTSDNTAGNLILDAIGGP +VGLTNYLRTLKDDITRLDRRETALNEATPGDPRDTTTPDAMASTLQRLLLGEALSEASRL +TLQGWMLANTTGSDKLRAALPDDWQIADKTGGGGHGTNNDIAIIWPPNHAPLIVAVYLTE +SEAERAVRDAAIADVGRLLVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000757F666 +----ASSLAELERAAGGRLGVHVLDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV +ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP +AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA +QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLG-----PIVLTVYYTQ +ARADAKRKDDVIAAATRIAI--- +>[subseq from] Uncharacterized protein n=1 Tax=Eimeria acervulina TaxID=5801 RepID=U6GQT8_EIMAC +------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Alcanivorax sp. ZXX171 TaxID=2695858 RepID=UPI001370DB43 +----IDTVKQVENRLQARVGVAVSDLGGDRTW-RHNADQRFPLASTFKVLACGALLHKVD +AGDESLERVIHFKKQDLVTYSPETQQHLDSGMTLGALCEAAITQSDNTAANLLLDRLDGP +AGLTRFLRGIGDDTTRLDRRETELNEGTPGDPRDTTTPDAMLATLRVLVFGDVLSESSRQ +QLLQWMKDDKIADALLRAGIPDDWTIGDKTGAGGHGSRAIIAVMWPPQQEPVLAAIYITE +TDASMDQRNAAIAEIGRALA--- +>[subseq from] TEM family class A beta-lactamase n=2 Tax=cellular organisms TaxID=131567 RepID=UPI0007AE5081 +--ETLVKVKDAEDQLGARVGYIELDINSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella aerogenes TaxID=548 RepID=A0A649UHK0_KLEAE +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEH- +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum sp. RV1423 TaxID=1443993 RepID=UPI0004B0392D +---VVSRLAKLEAGVNGRLGVEILDTASGKHW-GYRADERFPMCSTFKFLAASAVLKRVD +AGAEQLDRRIVYGEDVLVSYSPTTAKHVGGDLSLAQLCEAAITLSDNTAANLILRSIGGL +EPFNDFVASLGDGVTRLSRFETELNSAIPGDPRDTTTPAAMTANLHKVLLGDVLSPASRR +QITAWMAANKTGDQRLRAGMAPGWKVGDKTGSGDHGTTNTVAIIWPPQGKPLLASIYLTE +TKAPAERRNAVLADVGKLIV--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F4ZCJ5_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLREIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase SHV-13 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=BLA13_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAAERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010134DC3 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVYDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI00070C3E4B +haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAASALLKKSE +TQKGLMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGSP +AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA +QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ +PVKDAQSRREILAEAAKIAVSPf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZM37_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTATPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI00065A8599 +--SLDKQLAALEHSANGRLGIAMINSGAGTKI-LYRGAQRFPFCSTFKFMLAAAVLDQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLARGMTVSELCAATIQYSDNTAANLLIKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALRPAQRS +QLAAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATQIILS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Salmonella senftenberg TaxID=28150 RepID=U6BP97_SALSE +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGAS----- +>[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=Q8RJ46_KLEOX +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=2 Tax=Photorhabdus asymbiotica TaxID=291112 RepID=B6VKV8_PHOAA +--SLYKQLAELENSTKGRLGVTLINTANGQEI-QYRGDERFPFCSTFKLIVVAAVLHKSM +SQSELLAKHINYSETDLLSYAPIARKHLNQGMSITQLCAATLQYSDNTAVNLLIKELGGV +EAVNHFTQSLGDHTFRLDRWEPDLNSAIPDDHRDTTTPAAMAASVKKIVFGEVLAELQRD +LLIDWLKGNTTGDASIRAGVPTGWVVGDKTGGGDYGTTNDVAILWPPKGAPVILAVYFTQ +PQKDAESRRDVLASATRLVMEH- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007CBB3D0 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSPRSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Caballeronia terrestris TaxID=1226301 RepID=A0A158HLE8_9BURK +--SAASRLKALEDASKGRLGVSALNTADGSRI-DYRADERFAFCSTFKVVLSSAILTRSA +RDEGLLARRIRYGQSDIVANSPVTSKHVADGMTVGELCAAALQYSDNAAANLLIRLHGEP +ADVTAYARSIGDTEFRLDRMETELNTAIPGDPRDTTTPAAMALTLQRLALGNALGVAQRD +QLQTWMRANTTGDKRIRAGVPRDWQVADKTGTGDYGTSNDIAVLWPPAKPPIVLVIYFTQ +REQDAKARDDVLASAARIVAEKf +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0008464001 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAXERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Nissabacter sp. SGAir0207 TaxID=2126321 RepID=A0A4P8SMN7_9GAMM +hsQLQQQLAELEQRSGGRLGVALIDTADNWQF-SYRGAERFPMCSTSKVMVAGKLLKQSE +HEPGLLGQRVDIHDSDLVNYNPITQQHVGGSMSWGELSAAALQYSDNTAMNKLLGGLGGP +QHITAFARTLGDSQFRLDRTEPTLNTALPGDPRDTTTPVAMAESLRKLALGSALAAPQRE +QLVVWMKGNTTGKASIRAGLPAEWQTADKTGSGDYGTTNDIAVIWPKNHAPLVLVTYFTQ +PLPDAAGNKAVLADAARIVTQGy +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2S1JDQ1_ECOLX +--NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE +MDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAELSAAAIQYSDNTAMNKILEHLGGP +AKVTEYARTIGDKTFRLDRTEPTLNTAIPSDKRDTTSPLAMAKSLQTLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPATWVVGDKTGIGDYGTTNDIAVIWPANHAPLVLVTYFTQ +PQQNAEARKDVLAAAAKIVTE-- +>[subseq from] Extended spectrum beta-lactamase CTX-M n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTY4_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFATCITSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTN-- +>[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000841FF7C +-----TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV +ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP +SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAVSLRVLALGDAL----RA +QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ +ARADALAKDDVIAAATRIAI--- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI00082801BC +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERKRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX88_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEVLPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Paenibacillus bovis TaxID=1616788 RepID=A0A172ZME5_9BACL +--SLASRFRALEQQHQARLGVYAIDTGTGKVV-AYRHNERFAFASTYKALAAAAVLQQNS +--IADLDRVITYSADDLVEYSPVTEKHVDTGMTLREICEAAIQYSDNTAGNILFQELNGP +AGFQQTLRQLEDRTTRSERIEPELNAAVPGDARDTSTPRALVRDLRLFTTGKVLSQDKRQ +LLAEWMKGNTTGNDLIRAAVPKGWVVGDKTGSASYGTRNDIAVVWPPGRAPIIIAVLTGH +TDKEAKADNELVAKAAKIALD-- +>[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=Q5I5D9_SALER +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPIDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Kerstersia gyiorum TaxID=206506 RepID=A0A649UIV6_9BURK +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEH- +>[subseq from] Beta-lactamase n=4 Tax=root TaxID=1 RepID=A0A4U9LD97_ECOLX +------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E05418 +--SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLVKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDASIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATKIILS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL62_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGAS----- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. MOS003 TaxID=2133946 RepID=A0A2T2PZ56_9BRAD +-----EAIKQLELKSGGRLGVSVLDTTTRVPI-HHKGDERFPMCSTFKVLASAAILKAAS +SKLETLERRVRIDQADLVENSPITREHIGGEMTLRELCDAAITRSDNTAGNALLKNIGGP +AGLTSFARSLGDDITRLDRTETELNEATPGDPRDTTTPNAMAANYRRLLLGDVLPPEGRD +QLGQWLIANKTGDTRLRAGLPQGWRVGDKTGAGENGTTNDVAIVWPPKRSPLIIAVYLTG +ASLDPNGRNDVIASVGREVGKAf +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E490C6 +--SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLVKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDASIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATKIILS-- +>[subseq from] SED family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00128D753B +--QVQEKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE +TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT +SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA +QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ +PQQDAKWRKDILAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sonorensis L12 TaxID=1274524 RepID=M5PIH6_9BACI +--ALNDAFAKLEDQFDARLGVYALDTGTNQTI-AYRADERFAYASTHKALAVGALLQQKS +--ITDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELCDASIRYSDNTAGNLILKQIGGP +DGFKKSLRKIGDKVTNPERFEPELNEVKPGETHDTSTPKALATSLKAFTIGDALPKEKRM +MLIDWLKRNTTGDALIRAGVPKGWEVGDKTGAGSYGTRNDIAVIWPPKGDPIVLAILSSR +DQKDAEYDDKLIAQAAKEVID-- +>[subseq from] Beta-lactamase n=1 Tax=Marinobacter hydrocarbonoclasticus TaxID=2743 RepID=A0A1M2V1K3_MARHY +hnSLIKTVEKVADDLEAHVGFAAYDMESGQRW-EYHADQRFAMSSTFKTLACAALLHQVD +RGQVNLGRKVHVSESDLVTYSPITEKHTGGEMTLSDLCEATLTTSDNTAANLVLRELGGP +EAVTSFARDLGDDVTRLDRWETELNEALPGDTRDTTTPNAMVRNLQTLLLGDALSEPSRE +QLRDWLEGNQVADGLFRAAVPEGWTVADRTGAGGFGSRSITAVIWPPERQPIIVALYLTQ +TEASFEERNAAIAEIGEAIV--- +>[subseq from] Beta-lactamase n=2 Tax=Caballeronia udeis TaxID=1232866 RepID=A0A158HC11_9BURK +----QDQLKQLESSAGGRLGVAALNTADGKLV-NYRADERFPLCSTFKLMLVSAVLEQSE +SQKGLLERRIHYARSELLSWAPITKKQVATGMTVAELCAATLQYSDNTAANLLMKLVGGP +ETVTAYARSIGDNQFHLDRREPDLNSAIPGDPRDTSTPAAMAHSLQRVTLGDALGASQRS +QLQTWLLGNTTGAGKIAAAMPAHWMIGDKTGSGDYGTTNDIGVIWPPGKPPIVLAIYLTQ +REQDAKARDDVVASAARIVVAAf +>[subseq from] SHV-12 n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A6C0L4K1_KLEOX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000C6C884B +--ETLVKVKDAKDQLGKRVGYIELDLASGKILvSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTAASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Uncharacterized protein n=2 Tax=cellular organisms TaxID=131567 RepID=A0A2A2K9F8_9BILA +---LRKALQQLEATTGSTIGLWALDTGSGQQL-AWRAEERFAFCSTFKAILAGAILHRSQ +AEPGLLERRIAYGAEQLVVYSPVTEKHVGAGMTVAGLCAAAVQYSDNTAGNLLLELVGGP +SGLTAFTRSLGDPRFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLGDGLAAAERQ +QLQDWLKGNTTGDARIRAGVPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWIVVVFSRG +TKADAPWNSETIAAATRVVVEAw +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=Q4JL90_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDCWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Photorhabdus luminescens TaxID=29488 RepID=A0A0A0CVB0_PHOLU +--SLHKQLAELENSTKGRLGVMLINTANGQEI-QYRGDERFPFCSTFKLILAAAVLHKSM +SQPELLAKHIHYRESDLLSYAPITHKNLNQGMSVAQLCAATVQYSDNTAANLLIKELGGL +EAVNRFTQGIDDPAFRLDRCEPDLNSAIPGDLRDTTTPAAMAASVKKIVLGEVLGASQRE +QLIVWLKGNTTGDASIRAGAPAGWIVGDKTGAGDYGTTNDVAVLWPPKGAPVVLAVYFTQ +PQQDAESRRDVLAAATRLVMAH- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD2B591 +-dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD +RGKEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +DGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRQ +QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE +AKAPLDDLNPVFADIGRIVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=A0A3W2F3P6_SALER +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTVELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. H4 TaxID=2035449 RepID=UPI000D0FF826 +-dDVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP +AALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLINWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005FD0364 +--SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLVKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATKIILS-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007CBB6EA +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMISTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Kluyvera cryocrescens TaxID=580 RepID=UPI00068B26B2 +--SVEQKLAALEKASGGRLGVALIDTADDSQM-LYRADERFAMCSTSKVMAAAGVLKKSE +TEHNLLNKRVKINKSDLTNYNPIAEKHVGGSMSLSELSAAALQYSDNVAMNKLIEQLGGP +DGVTAFARQVGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGKALGDTQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLVLVTYFTQ +TQPKAESRRDVLASAAKIVTE-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2B5E53 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMISTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=Q5QQ30_KLEPN +--ETLVKVKPAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B4203F2 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMEDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3Q9HH75_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGAS----- +>[subseq from] Class A beta-lactamase SHV-224 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTK0_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAALARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI0012B9D1BB +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SHPDVVNKRLEIKKSDLVVWSPITEKHPQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Proteus sp. ZN5 TaxID=2697019 RepID=UPI0013E12865 +-nTIEEQLSTLEKYSQGRLGVALINTEDNAQI-TYRGEERFAMASTSKVMAVAAVLKASE +KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLGGP +AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEQDAKYRKDIIAKAAEIVTK-- +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00051AABC2 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPLTSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2P9E6B0_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Cobetia marina TaxID=28258 RepID=A0A4Y4GNA4_COBMA +-----ANLQEIEQRVGARLGVTVLDTADGRRV-SWRGDERFPMSSTFKVLACGNLLSRVD +ARQESLSRKVEIRPADLVTYSPVTERQVEGDMTLAALCRATITTSDNTAGNLILDAIGGP +VGLTNYLRTLKDDITRLDRRETALNEATPGDPRDTTTPDAMASTLQRLLLGEALSEASRL +TLQGWMLANTTGSDKLRAALPDDWQIADKTGGGGHGTNNDIAIIWPPNHAPLIVAVYLTE +SEAERTVRDAAIADVGRLLVS-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007DD69E6 +--ETLVKVKDAEDQLGAREGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Leminorella richardii TaxID=158841 RepID=A0A2X4XUF8_9GAMM +-dALQQKLADLEKSTGGRLGVALINTADNSQI-VYRGDERFAMCSTSKVMAAAAVLKQSE +TDSRVLSKKVAITKADLTNWSPIAKKHLGAGMTLAEMSAATLQYSDNTAMNKILTHLGGP +EKVTAFARSIGDTTYRLDRTEPALNSALPGDPRDTTTPLAMAKSLRSLTLDNALGETQRA +QLVEWMKGNTTGDASIRAGLPKNWIVGDKTGSGDYGTTNDIAVIWPENRAPLILVTYFTQ +PQQNAKARRDVLASAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A2W5EE87_AZOBR +---LPARFAAIERRVGGRLGVAVLDTATGQRA-GHRETEPFPLTSTFKLLAAAAVLARAD +AGQARLGQRIHYGREKLVTYSPETEKHAGEEMTLAAICEAAVTLSDNTAGNLMLEQLGGP +AGLTAWLRSIGDEVTRLDRWETALNEAVPGDPRDTTSPAAMLASLRKVTLGEVLSDEGRA +RLTGWLRANRTGDQRLRAGLPEGWQAGDKTGAGERGTNNDVGLLWPPGGAPILVAAYSTG +SAADGAARDAALAEVATAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=Q9F0F5_PROMI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLHCWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. UYPR1.413 TaxID=1080179 RepID=UPI000490347F +--AFEKQLAQIEAQVGGRLGVAILDTASGKQH-GWRMNERFPMCSTFKVLLASAVLTRKD +QGKEELGRKVVYAKDVVVANSPVSGPRAGGDMTVSELCEAAITRSDNTAANLLLESIGGP +AALTAFVRGMGDKVTRLDRNEPTLNEALDGDPRDTTTPAAMLADLRALLLGEHLSAASRE +QLTAWLVANKTGDARLRAGLPKDARVGDKTGTGERGTSNDIAIVWPAGRPPILVTVYLTG +ATASAAQRDAAIAKVGALVAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. CFH 70021 TaxID=2202148 RepID=A0A2S2CMP3_9PROT +--ALRDAMAALERRSGGRLGVAVLDTGSGRRF-DWRGGERFPMCSTFKFLLAAAVLKRVD +QGRDSLERRIPVTAADLVPYAPFAEGRVNGTPTVAELCEAAVTLSDNVAANLLLSAVGDP +AGLTAFVRTLGDTHSRLDRNEPELNSSIPGDPRDTTTPNAMVHSMGRLMLGDALRPASRD +QLIAWMVANRTGDKRLRAGLPQGWRVGDKTGTGN-GSFNDIAIVWPAGKPPLLVASYLTQ +TPKGFAQGDAVHADVAKAVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. WL19 TaxID=2603896 RepID=A0A5C8UFV9_9RHIZ +-rDLADRFARIEEASGGRLGIGLLDTGSGAHA-AHRGDERFPLCSTFKVLAAGAVLARVD +RGEDGLDRRLRYEPREVVPYSPVSGPRAGGEMTIAELCEAAVTLSDNTAANLLLRTMGGP +AGLTGHIRGFGDATTRLDRTEPDLNEAAPGDARDTTTPLAMAETLRRLVLADALSPASRA +LLTAWLVGCRTGDARLRAGLPKDWRIGDKTGSGENDTANDVAVIWPPRRPPLVLTVYLTG +ARTSSEARSATIASVARAVA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Herbaspirillum hiltneri TaxID=341045 RepID=A0A561JZ53_9BURK +---VVSRLAKLEASVAGRLGVEILDSGTGRRW-GYRADERFPMCSTFKFPAASAVLRRVD +TGAEQLDRRIVYGEDVLVNYSPTTSKHVGGDLSLAQLCEAAITLSDNTAANLILHSLGGL +GPFNKFVRSLGDDTTRLDRFETELNTSIPGDPRDTTTPTAMTGNLQKILLGDALSAASRR +QITAWMLANKTGDRRVRAGMQPGWKVGDKTGSGDYGTTNTVAIIWPPQGAPLLASIYLTE +TRAPEEQRNAVLAEVGKLIV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 103mf TaxID=1761751 RepID=A0A1I6TEM7_9BACI +--ATHREFAQLEKNFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS +--IDKLNEVITYTKDDLVTYSPVTEKHVDTGMTLGEIAEAAIRYSDNTAGNLLFKKLAGP +KGFEKALRQIGDRVTMADRFETELNEAIPGDIRDTSTPKALATDLKAFTVGNALPADKRK +ILTDWMRGNTTGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR +DKKDATYDNELIAQAAKVTIN-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q93MS4_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKLw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YE68_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDEAFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000CDAD3AB +------KVKDVEDQVGAGVGYIEVDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A1I6W9Y5_9BACI +--ATHRELVQLEKKFDARIGVYAIDTGTNRTV-AYRPNERFAYASTFKALAAGAVLQQNS +--IDKLDEVITYTKDDLVTYSPITEKHVDTGMTLGEIAEAAICYSDNTAGNLLLKKLNGP +NGFEKALRQIGDRVTMADRFEPDLNEATPGDIRDTSTPKALATNLKAFTIGNALPTDKRK +ILTDWMRGNTTGDQLIRAGVPKGWEVGDKSGAGSYGTRNDIAIVWPPNREPIIIAILSSR +DTKDATYNNELIAQAAKITIN-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C7F41E5 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHPADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A193CHV5_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTNQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Thalassospira xianhensis MCCC 1A02616 TaxID=1177929 RepID=A0A367UCN7_9PROT +--RLMDAIHAVETRLGARVGVSILNVENGREW-QYREDERFPLTSTFKLLACAAVLHKVD +FGTETLDRRITYGAEDLVPYSPITEKHVDGGMTIGELCEATLHLSDNTAANLILDALGGP +GKLTAYLRDIGDDVTRLDRIEPDLNTAKPGDPRDTTTPDAMRALLAYLLLGDALSPESRQ +LLEDWLMGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIAAVIWPPEQKPVIVAIYITQ +TSASMDERNAAIADLGQEIA--- +>[subseq from] Beta-lactamase n=1 Tax=Blastochloris viridis TaxID=1079 RepID=A0A0H5BBF8_BLAVI +--ATERALADLERRFGGRLGVAILDTGSARRA-SHRGSERFALCSTFKVLAAAVVLARVE +RGDDSLDRRILYRRDDLVPYSPVTERRLADGMTLGELCEATMTLSDNTAANLLLDSFGGP +AAVTAMLRGLGDGATRLDRREPALNDVPPGEERDTTTPQAMGDTLLRLVVGNALAPASRH +RLIEWLVNCKTGDQRLRAGVPAAWRVGDKTGSGPRGEANDVAVMWPPGRAPMVVTAYYVN +PAGSADARNAVLAEVGRLVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia nodosa TaxID=392320 RepID=UPI00048A18AF +--TLEKQLAAIEAQAGGRLGVAMLDTANGHVR-GWRMHERFPMCSTFKVLLASAVLTRKD +HGKEDLARKVVYTPAQVVSYSPVSGPRAGGEMTVAELCEAALTRSDNTAANLLLESIGGP +SAITTFARSIGDPVTRLDRNETTLNEAIPGDPRDTTTPAAMVANLRELLLGERLSAASRE +QLIAWLVANKTGDARLRAGLPKDWRVGDKTGTGDRGTANDVAIVWPTGRAPILVTTYLTG +ATASSAQRDAAIARVGVWVA--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0C5C1Y7_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYTPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Curvibacter gracilis TaxID=230310 RepID=UPI000488E180 +-----GQWQALERESQGRLGVAVFDTQSGAWL-GHRLDERFAMCSTFKWLAAAQVLRRVD +QGLERLDRRIEFGREALLPWSPVTEKHAGGAMTVGELCHAAITVSDNAAANLLLRSFGGP +EGLTRFARQLGDPVTRLDRWEPELNEATPGDPRDTSSPRAMVELLRQAVLGPALSAGSRQ +QLAQWLQATQTNLKRLAADLPAAWRVGSKTGTGAHGSTNDVGLYWPPDRGPIVVAVFLTE +SKASLEAREAVIAQVARRVH--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL87_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAXIGASLIKH- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00098385B7 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNSQIAEIGASLI--- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL80_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAXIGASLIKH- +>[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=Q6UK84_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGEHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. URHB0020 TaxID=1380385 RepID=UPI000482AF5E +--ELSQRFAKIEKTSGARLGVLVLDTGSGVRA-GHREDERFPMCSTFKFLAAAAILARVD +QQRERLDRRVVFHERELVDNSPVTEKHVGGAMTVAALCEAAITRSDNTAGNLMLASIGGP +AGLTRYTRSLGDKQSRLDRTETALNEARPGDPRDTTTPAAMLGDMQKILLGAALSLPSRA +QLLRWLDANQTGGQRLRAGVPADWVVGDKTGSGDQGTANVIAILRPPGRAPILAAVYLTE +STASMEFRNATIASVGAAFAK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A221SNF6_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQKDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGA------ +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A7LLU6_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNRAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q9R770_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYMTG +GQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RIY3_9BACT +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sophoriradicis TaxID=1535245 RepID=UPI000BBD5FBC +--NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP +AALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLINWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. IE4771 TaxID=1301032 RepID=A0A060HY47_9RHIZ +--NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP +AALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLINWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. WYCCWR10014 TaxID=1825933 RepID=A0A198YLE4_9RHIZ +--NIDRRLAALEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVNYGKDKLVDYSPISEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGQTGSLGDIAVIWPPDRGPIVAAVYISQ +ATVPAKELNPLFAEVGRMIVE-- +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00062CB00B +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKXAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B958953 +-----EQIKQSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6Z9J1_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDGQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia plantarii TaxID=41899 RepID=UPI0006D8AC7A +-----RQLAALDGSFDGRIGVAALDTGSGARL-LHRADERFAFCSTFKTILVSAVLTRAA +GDPRLLSSVIRYRAQDLVRYSPVSEKHVDTGMSVAGLCAAALQYSDNSAANLLIRMVGGP +AAVTAYARSIGDRRFRLDRIETELNDAVPGDERDTTTPAAMLDTLRRVTLGDALDASGRA +RLISWMLGNTTGDARIRAGVPAGWRVADKTGSGDYGSANDVAVIYPPRRAPIVLVVYTTR +DRKDAEYDNAAIASAARIVTAAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q93K44_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001082D4C0 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKSGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A224A9A1_SHISO +------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLI--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q71LW4_KLEPN +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADRVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Ghvi TaxID=1855319 RepID=A0A1I5K9T4_9BRAD +-----DAIKQLELKSGGRLGVSVLDTNTGVPI-HHRGDERFPMCSTFKVLASAAVLKAAG +SKLEGLERRVRIEQADLVEYSPVTGKHVGGEMSLRELCEAAITMSDNTAGNALLKNIGDP +AGLTSFARSLGDDITRLDRIETELNEATPGDPRDTTTPNAMAANYRRLLLGDVLLPEGRD +QLGKWLIANKTGDTRLRAGLPHGWRVGDKTGAGEHGTTNDVAIVWPPERSPLIIAVYLTG +ASLDPNGRNDVIASVGREVGKAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A218MJA3_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGSLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. FT58W TaxID=2654254 RepID=UPI001264F619 +---PQQQLAALEQAAGGRLGISAVNARTGATV-AHRADERFPMCSTFKAMLAAAILARQA +GDATLLAQRISYQKSELVTYSPITEKHLADGMTVAELCAATVQYSDNSAANFLMKLLGGP +QAVTAFARSIGNDVFQLERWETELNSAIPGEVRDTTSPTAMTHSLQQLLLGEALPASQRQ +QLESWMRGNTTGDQRIRAGLPAGWSAADKTGSGAYGTVNDIGVAWSPDGTPLVIAIYYTR +EVKNAPTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium gallicum TaxID=56730 RepID=A0A1L5NG50_9RHIZ +-dDIERRLAELEKRTGGRLGVSVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD +KGEENLERRVIYDQDKLVSYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLLLESVGGP +KALTKWLRSIGDRATRLDRWETALNEGKKGDPRDTTTPDAMLDTLGNLALGSVLSEPSRE +KLIEWMLANTTGDARLRAGLPGAWKVGDKTGTGDNGTAADIAIIWPKGRGPILVTAYIAE +ATAPVKELNLVFAEVAKIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F8SQ10_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AALTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPHNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YPP4_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLSLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] class A beta-lactamase n=1 Tax=Chromobacterium subtsugae TaxID=251747 RepID=UPI0006416144 +--SAAARLAALEADFGGRLGVCALDTASGAEL-GHRAGERFPFCSTFKAMLVGAVLARSA +KQPGLLAERIHYARRDLVEYSPRTEPHLADGMTVAELCAAAVQYSDNSAANFLLKLLGGP +AALTAYMRSIGDESFLLERWEPELNRAVPGEARDTSTPQAMAQSLRRLALGDALAPHAQR +QLVEWLRGNTTGAEKIRAGVPAGWVVGDKTGNGRYGSSNDIAVLWPPGRAPAVLTVFTTQ +ALEDAKQRHQVVAAAARIAAD-- +>[subseq from] Beta-lactamase n=2 Tax=Proteus vulgaris TaxID=585 RepID=Q52615_PROVU +-nTIEEQLNTLEKYSQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKASE +KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLGGP +AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDNSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEQNAKYRKDIIAKAAEIVTK-- +>[subseq from] class A beta-lactamase n=1 Tax=Verrucomicrobium sp. BvORR034 TaxID=1396418 RepID=UPI000679BC29 +----VSKLEGIEGQDGARLGVYALDLESGMEI-KHRAEERFPVCSTFKVILTSAILKQSV +QDAGLMTRRISYAKHELVTYSPVTEKHVEDGMTVEALCAAAMQYSDNTAANLLMKILGGP +GAVTAYARSIGDTQFRLDRWETELNTALPGDPRDTSTPAAMGHSLQKLAWGDGLPEAQRA +KLVEWMLGNTTGDKRIRVAVPPDWKVGDKTGSGDYGTANDIAILWPPGRKPIVLAIYHTQ +KAADAKWQNEAIAAAARVVLEAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A142FK11_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMSATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SED family class A beta-lactamase n=1 Tax=Citrobacter amalonaticus TaxID=35703 RepID=UPI000F66FBA4 +--QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE +TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT +SNVTAFARSIGDTTFRMDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA +QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ +PQQDAKGRKDILAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=C4NZW3_SALTM +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLEREIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=3 Tax=Enterobacterales TaxID=91347 RepID=Q6PW40_CITKO +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000A177262 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEH- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=I3WA87_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=3 Tax=Escherichia coli TaxID=562 RepID=A0A2H4FYM3_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B8CDA28 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPVGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Salmonella derby TaxID=28144 RepID=Q4GX46_SALDE +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDCWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A0B4UA24_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Shigella flexneri TaxID=623 RepID=Q3HLW6_SHIFL +--ETLVKVKDAEDQLGARVGYIELDLNGGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. Root434 TaxID=1736536 RepID=A0A0Q7HDK9_9BURK +--SAEAQLAELERASGGRLGVAGFHTGSGARI-QHRAHERFPLCSTFKLMLAAAVLERSA +KDVSLLARHIGYGKADLVSWSPITEKHVADGMTVAELCAATVQYSDNGAANLLLKMLGGP +ATVTAFARGIGDQAFRLDRTEPELNTAIPGDLRDTTTPAAMSDSVQRLALGDALGTAQRE +QLKDWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPVVLSVYLTF +PQKDAKGRNDVIASATRIVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Cobetia marina TaxID=28258 RepID=A0A4U1M2X5_COBMA +-----ANLQEIEQRVGARLGVTVLDTADGRRV-SWRGDERFPMSSTFKVLACGNLLSRVD +ARQESLSRKVEIRPADLVTYSPVTERQVEGDMTLAALCRATITTSDNTAGNLILDAIGGP +VGLTNYLRTLKDDITRLDRRETALNEATPGDPRDTTTPDAMASTLQRLLLGEALSEASRL +TLQGWMLANTTGSDKLRAALPDDWQIADKTGGGGHGTNNDIAIIWPPNHAPLIVAVYLTE +SEAERTVRDAAIADVGRLLVS-- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q6WSQ7_ECOLX +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGSSGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A3FFR3_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQHLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0001FD28D0 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVEYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. 54 TaxID=2035212 RepID=A0A2G6X6R7_9BURK +--DAEAQLAELERACGGRLGVAGFHTGSGTRL-QHRAHERFPLCSTFKLMLAAAVLERSA +TDASLLGRRISVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP +AAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPAAMSDTVQRLALGDALGAPQRE +QMRDWLLGNTTSTERFLAGVPAGWRVGDKTGAGSYGTTNDVGVLWPPSGAPLVLSVYLTF +PDKDAKGRNDVVASATRIAVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL92_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLI--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella spallanzanii TaxID=2587528 RepID=A0A5P1KAR8_9ENTR +-nAIQQKLADLEKNTGGRLGVALIDTTDNSQV-LYRGDEHFAMCSTGKVMAAAAVLKQSE +ADNQVLNKRLEIKKSDLVVWSPVTEKHLQSGMTLAELSAAALQYSDNTAMNKMIGYLGGP +EKVTAFAHSIGDVTFRLDRTEPTLNTAIPGDERDTTTPLAMAESLHKLTLGYALGEQQRA +QLVTWLKGNTTGGQSISAGLPAGWVVGDKTGAGEYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=B2LUM6_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADRTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI000B49405B +--AIHQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGEQSIRAGLPASWVVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8VP57_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDKQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGGRGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. PMC12 TaxID=2126319 RepID=A0A2P1V6Y4_9BURK +--SAEAQLAELERSCGGRLGVVAFNTDSGARL-QHRAHERFPFCSTFKLMLAATVLERSA +KDPSLLARRISYGKADIIPNSPVTEKHVSDGMTVAALCAATIQYSDNAAANLLMKMLGGP +ADVTAFARTIGDQVFRLDRWETELNTAIPGDLRDTTTPAAMADSVQRLVLGDALAGAQRS +QLQTWLLGNTTSAERFMAAVPPGWKVGDKTGAGSYGTNNDVGVMWPPAGAPLVVAVYLTF +PDKDAKNRNDVVAAAARIAVN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=H6D900_9BACT +----LLKVKDAEDQLGARVGYIELDLNSNKILeSFRPEERFPMMSTFKVLLCGAVLSRAD +AKQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium pachyrhizi TaxID=280333 RepID=UPI00128EC656 +-----------------RLGVAVLDMETGLRA-SRRGDERFPMCSTFKAMASAAVLHRVD +RGETSLEQRVQIEAKDILAYAPVTKGRVGSAMTLSELCAAAITLSDNTAANLLLREIGGP +AGFTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKDLQRVLLGDVLSAASRQ +KLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG +ASAPMETCNEVIANVARAVAN-- +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI000669003D +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella spallanzanii TaxID=2587528 RepID=A0A5P1KAV5_9ENTR +-nAIQQKLADLEKSTGGRLGVALIDTTDNSQI-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNKDVVNKRLEIKASDLVVWSPVTEKHLQSGMTLAELSAAALQYSDNTAMNKMIGYLGGP +EKVTAFARSIGDVTFRLDRTEPALNTAIPGDERDTTTPLAMAESLHKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PLQDAKSRKDVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Luteimonas sp. LNNU 24178 TaxID=2605430 RepID=UPI0011F04262 +----APALAELERDSGGRLGVAVLDSGSGQQA-GRHADERFPMCSTFKFLLAAAVLQQVD +RGRERLDRNVPIAESDLVPHSPQTEKHVGAEMRVGDLCRATMIRSDNAAANLLLRTLGGP +AGLTRFVRELGDPHTRLDRWEPELNSAVPGDPRDTTTPAAMARNLQRLLLGDVLHDASRA +LLTGWLVDNRTGDARLRAGLPKRWRVGDKTGTSILGTANDIAIVWPPGRSPLLITCYLTG +AAPDIGAMDAVHTAIARAVAATy +>[subseq from] Beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=D2D0D6_RAOTE +heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD +AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAELCAAAITLSDNTAANLLLASVGGT +QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLHNLLTGSVLSAASRQ +QLRSWMVDDKVAGPLLRSTLPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMDERNRQIAEIGETLVKHw +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea TaxID=53335 RepID=UPI00067C4E8C +---LAQPVRQLEHAAGGRLGVAAIDTGDGSVF-TYRGNERFPLCSTSKVFTVAAILKKAE +TAQGLLNENIAIRHADLVNYNPVTEKQVGGTMTVAELSAAALQYSDNAAMNKLLTHLGGP +HAVTAFARSIGDNTFRLDRTEPTLNTAIPGDTRDTTSPTAMAQSLQKLVLGTALGPAQRQ +QLADWMKGNTTGTYSIRAGLPADWVVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +TDKHAASRKDVLASAAKIIASGy +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q8GNS6_KLEOX +-nAIQQKLADLEKSTGGRLGVALIDTTDNSQI-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNKDVVNKRLEIKASDLVVWSPVTEKHLQSGMTLAELSAAALQYSDNTAMNKMIGYLGGP +EKVTAFARSIGDVTFRLDRTEPALNTAIPGDERDTTTPLAMAESLHKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PLQDAKSRKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A224A7P2_SHISO +------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLI--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3LUL0_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCTAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=Q9RMS2_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMGDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea stewartii TaxID=66269 RepID=UPI00068CC1D7 +---LAQPVRQLEHAAGGRLGVAAIDTGDGSVF-TYRGNERFPLCSTSKVFTVAAILKKAE +TAQGLLNENIAIRHADLVNYNPVTEKQVGGTMTVAELSAAALQYSDNAAMNKLLTHLGGP +HAVTAFARSIGDNTFRLDRTEPTLNTAIPGDTRDTTSPTAMAQSLQKLVLGTALAPAQRQ +QLADWMKGNTTGTYSIRAGLPADWVVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +TDKHAASRKDVLASAAKIIASGy +>[subseq from] Beta-lactamase n=1 Tax=Pantoea sp. PNA 03-3 TaxID=2135460 RepID=A0A2V3QGU9_9GAMM +---LAQPVRQLEHAAGGRLGVAAIDTGDGSVF-TYRGNERFPLCSTSKVFTVAAILKKAE +TAQGLLNENIAIRHADLVNYNPVTEKQVGGTMTVAELSAAALQYSDNAAMNKLLTHLGGP +HAVTAFARSIGDNTFRLDRTEPTLNTAIPGDTRDTTSPTAMAQSLQKLVLGTALAPAQRQ +QLADWMKGNTTGTYSIRAGLPADWVVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +TDKHAASRKDVLASAAKIIASGy +>[subseq from] SED family class A beta-lactamase n=1 Tax=Citrobacter sp. JT3 TaxID=1451265 RepID=UPI0005C523EE +--QVQEKLTALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE +TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT +SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA +QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ +PQQDAKGRKDILAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q6GWS9_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E90A47 +--SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRYVLASATKIILS-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2F4_9BACT +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRT +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q09Q13_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERDRQIAEIGASLIKHw +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000E2B887D +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSQALSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6ALA9_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRXD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKH- +>[subseq from] Beta-lactamase n=1 Tax=bacterium RRLBTTh23 TaxID=342578 RepID=Q3S2X1_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMEERNRQIAEIGLSLIKHw +>[subseq from] TEM family class A beta-lactamase n=4 Tax=Bacteria TaxID=2 RepID=UPI000DE5E0F6 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITSSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00004C2C83 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVAASPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WXQ3_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLAPRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGGRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=V5N2H6_KLEPN +-----EQIKQSESQLSGRVGMIEMDQASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter amalonaticus Y19 TaxID=1261127 RepID=M1K0S5_CITAM +-tQIQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKAMVAAAVLKQSE +TQHDILQQKMAIKKADLTNWNPVTEKYVDKEMTLAELSAAALQYSDNTAMNKLLEHLGGT +GNVTAFARSIGDTTFRLDRTEPELNTAIPGDERDTTTPLAMAKSLHKLTLGDALADTQRA +QLVAWLKGNTTGGQSIRAGLPENWVVGDKTGGGDYGTTNDIAVIWPEGRAPLILVTYFTQ +PQQDAKGRKDVLAAAAKIVTQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea stewartii TaxID=66269 RepID=UPI0006D0552F +---LAQPVRQLEHAAGGRLGVAAIDTGDGSVF-TYRGNERFPLCSTSKVFTVAAILKKAE +TAQGLLNENIAIRHADLVNYNPVTEKQVGGTMTVAELSAAALQYSDNAAMNKLLTHLGGP +HAVTAFARSIGDNTFRLDRTEPTLNTAIPGDTRDTTSPTAMAQSLQKLVLGTALAPAQRQ +QLADWMKGNTTGTYSIRAGLPADWVVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ +TDKHAASRKDVLASAAKIIASGy +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0013BB1053 +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPAKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZFW7_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKXLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAINKLIAQLGGP +GGVTAFARAIGDETFXLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRR-------------- +>[subseq from] Beta-lactamase n=3 Tax=Klebsiella oxytoca TaxID=571 RepID=Q8RSU7_KLEOX +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00115BCABF +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQHLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T607_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTPMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI00119F37F9 +----GNQLAELERKSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ +TQPDLLNKHIKYRESDLLSYAPITRKNLAHGMTVSQLCAATMQYSDNTAANLLIKELGGV +ESVNAFARSIGDQAFRLDRLEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALPATQRE +QLTQWLKGNTTGAETIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPTQGAPIVMVVYFTQ +REKDAKPRRDVLAAATKIVL--- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6A2TGG8_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAAPIEHw +>[subseq from] Beta-lactamase n=2 Tax=unclassified Pseudomonas TaxID=2583993 RepID=A0A2V4T430_9PSED +-----ARLKQLEGSFAGRLGVVALNTGNGEVL-SYRGEERFPLCSTFKAMLAAAILQRSS +LTPGLLQERIRYQKSDLVSYSPISEQHLQDGMTVAELCAATVQYSDNGAANLLMKLLDGP +EGVTTFARSIGDHHFRLERWETELNTAIPGDLRDTTTPLAMVHSLHKLVLGEALPAPQRQ +QLQDWLRGNTTGGTRIRAGVPATWQVGDKTGTGDYGTSNDVAVLWPPGKAPVVLALYLTQ +DAKDASPRNETLVAATRIVVD-- +>[subseq from] Extended spectrum beta-lactamase CTX-M n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L031_9BACT +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCNTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPCDTTSPRAMAQTLRNLTLGKALGDSQRA +QLATWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLAPAAKIVTD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Serratia sp. Leaf51 TaxID=1736224 RepID=A0A0Q4MHQ4_9GAMM +-kAVQQKLAELEKSTGGRLGVAMIDTASNTQT-LYRADERFAMCSTSKVMAASGILKASE +TDKNLLNKHVDIKKSDLVNYNPITEKHLDSGMTLGELGAAAIQYSDNVAMNKLIAHLGGP +AKVTQFARSLGDETFRLDRTEPSLNTAIPGDKRDTTSPLAMAESLRKLTLGNALAEPQRA +QLVEWLKGNTTGAASIRAGLPATWQVGDKTGSGDYGTTNDIAVIWPDNHAPLILVTYFTQ +PQQDAKARKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Ewingella sp. SMO-1 TaxID=1332052 RepID=R4V074_9GAMM +-kAVQQKLADLEKSTGGRLGVAMINTADNSQT-VYRGEERFAMCSTSKVMAASAYLKASE +QDKNLLNKHVDIKKSDLVNYNPITEKHLDTGMTLGELGAAAIEYSDNVAMNKLIAQLGGP +AKVTQFARSIGDETFRLDRTEPTLNTAIPGDKRDTTSPLAMAQSLRKLALGDALAEPQRA +QLVAWLKGNTTGAASIRAGLPASWTVGDKTGSGDYGTTNDIAVVWPDNHAPLILVTYFTQ +PQQDAKARKDVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium symbiodeficiens TaxID=1404367 RepID=UPI00140FEE35 +-----EAIEQLELKSGGRLGVSVLDTMTGVPI-HHKGDERFPMCSTFKVLAAAAILKAAG +SKPEALERRVRIEQADLVEYSPVTREHIGGEMTLRELCDAAITRSDNTAGNALLKNIGGP +AGLTSFARSLGDDITRLDRTETGLNEAKPGDPRDTTTPNAMAANYRRLLLGDVLLPEGRD +QLGQWLIANKTGDTRLRAGLPQGWRVGDKTGAGENGTANDVAIVWPPKRSPLIIAVYLTG +ASLDPNGRNDVIASVGREVGKAf +>[subseq from] Beta-lactamase n=2 Tax=Rhizobium leguminosarum TaxID=384 RepID=Q1MJL1_RHIL3 +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPAKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 TaxID=484021 RepID=A0A4P1LYI7_KLEPN +-----EQIKQRESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTALLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=A0A5Q3LGS1_RHIML +-dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +DGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRQ +QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE +AKAPLDDLNPVFADIGRIVAD-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI0007D6ECB0 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZI91_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNLQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A3E1SYG1_KLEOX +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPANWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5R1MD38_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGA------ +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia canariae TaxID=2607663 RepID=UPI001318F282 +--TLDKQLAELERGANGRLGIAMINTANGTKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ +SQPNLLDKHINYHESDLLSYAPITRKNLAHGMTVAQLCAATVQYSDNTAANLLIKELGGV +EAVNQFARSIGDQMFRLDRWEPDLNTAVPNDPRDTTTPAAMAMSMNKLVLGDALLPAQRN +QLAVWLKGNTTGDATIRAGAPKDWVVGDKTGSGDYGTTNDIAVLWPTQGAPVVLVVYFTQ +REKDAKPRHDVLASATKIML--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium amphicarpaeae TaxID=1404768 RepID=A0A2U8PT95_9BRAD +--SLIEAIKQLELKSGGRLGVSVLDTMTGVPI-HHKGDERFPMCSTFKVLASAAILKAAG +SKLEALERRVRIEQADLVEYSPVTREHIGGEMTLRELCDAAITRSDNTAGNALLKNIGGP +AGLTSFARSLGDDITRLDRTETELNEAKPGDPRDTTTPNAMAANYRRLLLGDVLLPEGRD +QLGQWLIANKTGDTRLRAGLPQGWRVGDKTGAGENGTANDVAIVWPPKRSPLIIAVYLTG +ASLDPNGRNDVIASVGREVGKAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium anhuiense TaxID=1184720 RepID=UPI000471B3F0 +-dDIQHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGEEKLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPEAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGPNGTLGDIAVIWPPDRGPIVAAVYIAE +ATAPVTELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. F16(2018) TaxID=2093746 RepID=UPI001119AF78 +---LRKALQQLEATTGSTIGLWALDTGSGQQL-AWRAEERFAFCSTFKAVLAGAILHRSQ +AEPGLLERRIAYGAEQLVVYSPVTEKHVGAGMTVAGLCAAAVQYSDNTAGNLLLELVGGP +PGLTAFARSLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLGDGLAAAERQ +QLQAWLKGNTTGDARIRAGVPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG +AKADAPWNSETIAAATRVVVDAw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A224A851_SHISO +------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASL---- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=R4HET6_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRREPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium valentinum TaxID=1518501 RepID=A0A0R3LV23_9BRAD +--RLIGEIKRLESESGGRLGVCVLETATGTRH-VHRGDERFPMCSTFKALAAAAILARVD +AGNEQLTRRITFDASALVVNSPVTEKRVGGDMTVAEICDAAVTRSDNTAGNLLLAGIGGP +SGLTAFARSLGDEVTRLDRDEPSLNEALPGDPRDTTTPNAMASNLQALILGKALSAASRE +QLTAWLIANKTGDTRLRAGFAKGWRVGDKTGTGGRGTNNHVAVVWPPSAAPMVIAVYLTG +ATVSFEQQNAIVASVARAVS--- +>[subseq from] Beta-lactamase n=2 Tax=Pseudomonas TaxID=286 RepID=A0A2W7KNE3_9PSED +---LRKALQQLEATTGSTIGLWALDTGSGQQL-AWRAEERFAFCSTFKAVLAGAILHRSQ +AEPGLLERRIAYGAEQLVVYSPVTEKHVGAGMTVAGLCAAAVQYSDNTAGNLLLELVGGP +PGLTAFARSLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLGDGLAAAERQ +QLQAWLKGNTTGDARIRAGVPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG +AKADAPWNSETIAAATRVVVDAw +>[subseq from] class A beta-lactamase n=1 Tax=Streptococcus pyogenes TaxID=1314 RepID=UPI0011E6A449 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKQLTDGMTVRELCSAAITMSDNTAANLLLTTIGGT +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI001031C303 +--NIEHRLAALEKRTGGRLGVSVLDTDTSISL-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPAKELNPVFAEVGRMIVE-- +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella michiganensis TaxID=1134687 RepID=UPI000665E6E8 +--AIQQKLADLEKRSGGRLGIALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas viridiflava TaxID=33069 RepID=UPI000F0293DD +----LQRLIQLETTFAGRLGVVAINTGNGDVL-SYRGDEAFPLCSTFKAMLAAAILQRSV +LTPGLLEKRITYRKSDLVTYSPISEKHVQDGMTVAELCAATVQYSDNSAANLLLTLLDGP +EGLTTFARSIGDQHFRLERWETELNSAIPGDLRDTTTPLAMARSLQRLVIGDALPHMQRE +QLQAWLRGNTTGATRIRAGVPAAWQVGDKTGTGDYGTTNDVAVLWPPGKAPVVLTVYLTQ +NSKDASPRNETLAAATRAVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTB8_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2BD799 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2BD30B +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00115B6402 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I607_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase SHV-1 n=247 Tax=Bacteria TaxID=2 RepID=BLA1_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=14 Tax=Enterobacteriaceae TaxID=543 RepID=A0A3Q8GRH3_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E029A93 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000BD7F015 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=Q83YP9_ACIBA +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLHKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0011592A76 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001330315D +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A broad-spectrum beta-lactamase SHV-171 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000802882E +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2A5798 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000A26B829 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3LUK9_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADQRFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A9QW44_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSASSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ93_9BACT +--DVQQKLAELGRQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNLIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNPTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=A9ZTC6_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=3 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0A1IR40_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2P9EDA2_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase protein n=1 Tax=Rhizobium etli CNPAF512 TaxID=993047 RepID=F2AJL3_RHIET +--NVERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD +KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCEAAVTLSDNTAGNLLLESFGGP +AGLNDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +KLIAWLVASTTGKERLRAGLPADWKIGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPMKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Photorhabdus luminescens TaxID=29488 RepID=A0A2S8QYA3_PHOLU +--SLHKQLAELENSTKGRLGVMLINTANGQEI-QYRGDERFPFCSTFKLILAAAVLHKSM +SQPELLAKHIHYRESDLLSYAPITHKNLNQGMSVAQLCAATVQYSDNTAANLLIKELGGL +EAVNRFTQGIDDPAFRLDRCEPDLNSAIPGDLRDTTTPAAMAASVKKIVLGEVLGASQRE +QLIVWLKGNTTGDASIRAGAPAGWIVGDKTGAGDYGTTNDVAVLWPPKGAPVVLAVYFTH +PQQDAESRRDVLAAATRLVMAH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A3G2M3D6_9BACT +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A3G2M3L2_9BACT +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8RT90_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGADERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum humicireducens TaxID=1226968 RepID=A0A2R4VTL9_9PROT +---LAGRMAALEGRTGGRLGVAMLDTGTGRLQ-GWRVDERFPMCSTFKFLLAAAVLKAVD +QGRERLDRRIPVTSADLVPYAPFAETRLNGTPTVAELCEATMTLSDNVAANLLLPGVGNP +AGLTAFLRGIGDKTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMERLLVGDALRPDSSR +QLADWMIANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAILWPENRPPLLVASYLTQ +TAKDFNQHDSIHAEVARAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=C1KAC8_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. T3 TaxID=638269 RepID=UPI000EAF694F +---FEQRLARIEADIGGRLGVAMLDTASGLQA-GRRQDERFPLCSTFKFLAAAALLARQD +RGEDHLSERVVFSAADLVEYSPVTEGRVGGTMTLADICEAAVTRSDNTAGNLMLARLGGP +AGLTAFVRSLGDRQTRLDRYETALNEARPGDPRDTTTPAAMLADMRELLLGTALSPASRE +QLTAWLVANETGDARLRAGLPTAWRIGDKTGSGERGTANDIAILWPTAREPVLVTVYLTG +SETDMNRRNAAVAEVGAALAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. Tv2a-2 TaxID=113395 RepID=UPI0003F9193B +---LAEAFARVEADSGGRLGAGVLDTGTGATA-GHRQDELFPMCSTFKFLCVAAMLARVD +AGKEQLTRRIPVTSADLLDYAPVTKQHAGNDMTVAELCEAAVILSDNTAANLLLASMGGP +SAITQYARAIGDSVTRLDRTEPELNTAEAGDPRDTTTPAAMACNLQTLALGVALLPASRD +QLNKWLVGCKTGDARLRAGLPKDWRVGDKTGSGAHGTSNDIAVIWPAGRAPIMITAYLTQ +CPAGDDKRNAAIAAISKAVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Marinobacter sp. LZ-6 TaxID=2570350 RepID=UPI001108151B +hnALIKTVEKVADDIEARVGFAAYDLESGQRW-EYRADQRFAMSSTFKTLACASLLHRVD +TGQANLGRKVHVSESDLVSYSPITEKHAGGEMTLSDLCEATLTTSDNTAANLVLRELGGP +EEVTSFARHLGDDVTRLDRWETELNEALPGDNRDTTTPNAMVRNLQTLLLGDALSEQSRE +QLRDWLEGNQVADGLFRAAVPEGWTVADRTGAGGFGSRSITAVIWPPERQPIIVALYLTQ +TEASFEERNAAIAEIGEAIV--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q9RMS3_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRREPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERDRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella huaxiensis TaxID=2153354 RepID=A0A5P1KAU8_9ENTR +--AIQRKLTDLEKSSGGRLGVALINTTDNSQI-LYRGDERFAMCSTGKVMAAAAVLKQSE +VDNQVLNKRLEIKKSDLVVWSPVTEKHLQSGMTLAELSAATLQYSDNTAMNKMIGYLGGP +DKVTAFARSIGDVTFRLDRTEPALNTAIPGDERDTTTPLAMAESLHKLTLGNALGEQQRA +QLVTWLKGNTTGGQSISAGLPAGWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YE73_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQALRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6C7H2A2_ECOLX +-------------GSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGIGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZM40_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWLKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured Alphaproteobacteria bacterium TaxID=91750 RepID=A0A212JU75_9PROT +--AAEDPFAAIEARIGGRLGVAILDTGSGASW-ARRDDERFPLCSTFKVLAVGAVLARVD +AGAEDLDEPVPIAAAEVVEYSPVTGRRAGGEMRLAEICEAALTRSDNTAGNLLLKRIGGP +AGLTAFARTLDDAVTRLDRWETDLNAAIPGDPRDTTTPEAMVDDLGALLLGDRLSPTSAE +RLIAWMRANATGDAKLRAGLPAGWQVADKTGGGDHGATADVAVIWPPTGDPLIVAVYIHE +SPASFDARNAAIAEVARR----- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=R9UV61_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMXSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRXEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERDRQIAEIGASLIKHw +>[subseq from] Class A beta-lactamase n=2 Tax=Rhizobium meliloti TaxID=382 RepID=A0A3S2Q8E2_RHIML +-dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +QGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSEEGRK +QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE +AKAPLDDLNPVFADIGRIVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A516EKB2_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRREPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERDRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Rahnella sp. Larv3_ips TaxID=1896943 RepID=UPI000EFB5767 +-kAVQQKLAELEKSTGGRLGVAMIDTASNTQT-LYRADERFAMCSTSKVMAASGILKASE +TDKNLLNKHVDIKKSDLVNYNPITEKHLDSGMTLGELGAAAIQYSDNVAMNKLIAQLGGP +AKVTQFARSLGDETFRLDRTEPSLNTAIPGDNRDTTSPLAMAESLRKLTLGNALAEPQRA +QLVEWLKGNTTGAASIRAGLPATWQVGDKTGSGDYGTTNDIAVIWPDNHAPLILVTYFTQ +PQQDAKARKDVLAAAAKIVME-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTG5_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPAIMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B9512EA +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSLRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Marinobacter excellens TaxID=218670 RepID=UPI0007731AA7 +hnALIKTVEKVADDLEAHVGFAAYDVESGQRW-EYHADQRFAMSSTFKTLACAALLHQVD +RGQVNLGRKVHVSESDLVTYSPITEKHADGEMTLSDLCEATLTTSDNTAANLVLRELGGP +EAVTSFARHLGDDVTRLDRWETELNEALPGDNRDTTTPNAMVRNLQTLLLGDALSEPSRE +QLRDWLEGNQVADGLFRAAVPEGWTVADRTGAGGFGSRSITAVIWPPERQPIIVALYLTQ +TEASFEERNAAIAEIGEAIV--- +>[subseq from] Beta-lactamase n=1 Tax=Erwinia iniecta TaxID=1560201 RepID=A0A0L7T6H9_9GAMM +--TLAAQLSALEASANGRLGVALIDSGSSRQL-SYRGEERFAMASTFKALAAAAVLQRSV +EQPALLNKRIVYQQSELITYSPVTEKHLQQGMTVAELCAAAVELSDNTAGNILLREIGGP +QGITQLARRLGDNQTRLDRREPALNSAIPGDVRDTSTPLAMAGNLNQLALGKALPSAQQQ +LLIQWLKQSKTGAQSIRAGVPQGWQVGDKTGAGGYGTTNDLAILWPPQGKPLVLAVYFTQ +HNPQAEARRDVLASATRLVLAAw +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter freundii complex sp. CFNIH2 TaxID=2066049 RepID=A0A2K9P8P5_9ENTR +--QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKAMVAAAVLKQSE +TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAAALQYSDNTAMNKLLEHLGGT +RSVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA +QLVEWLKGNTTGGQSIRAGLPESWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ +PQQDAKGRKDILAAAAKIVTE-- +>[subseq from] Beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0000DABDFB +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVKYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. OV467 TaxID=2135592 RepID=A0A2V5B7I3_9PSED +---FHQRLEQLEATFAGRLGVVALNSNTGEVL-SYRGEERFPLCSTFKAMLAGAILQRST +LTPGLLGERIAYRKSDLVAYSPISEKHVQDGMTVAELCAATVQYSDNGAANLLMKLVDGP +EGVTTFARSIGDKHFRLERWETELNSAIPGDLRDTTTPLAMAHSLHRMVLGDALPAAQRQ +QLQEWLKGNTTGATRIRAGLPASWPVGDKTGTGDYGTTNDVAVIWPTAKAPLVLAIYLTQ +TRKDAAALNEPLAAATRIVLD-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0012328145 +-----EQIKHSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Yersinia TaxID=2653513 RepID=UPI0011A5A6D1 +--TLDKQLAELERGANGRLGIAMINTANGTKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ +SQPNLLDKHINYHESDLLSYAPITRKNLAHGMTVAQLCAATVQYSDNTAANLLIKELGGV +EAVNQFARSIGDQIFRLDRWEPDLNTAVPNDPRDTTTPAAMAMSMNKLVLGDALLPAQRN +QLAVWLKGNTTGDATIRAGAPKDWVVGDKTGSGDYGTTNDIAVLWPTQGAPVVLVVYFTQ +REKDAKPRHDVLASATKIML--- +>[subseq from] Beta-lactamase n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=A0A2J9S9L3_YEREN +--SLDNQLAELEKSSNGRLGLALINTDKGTKV-HYRGGQRFPFCSTFKLMLAAAVLGHSQ +SQPNLLSKHIIYRESDLLDYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL +EAVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRE +QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVVYFTQ +LKKEAEPRRDVLAAATKIVLAH- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0N9XKX3_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADELFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00144121C7 +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSESFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPLSEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATASAKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=UPI0007859A79 +--DAETQLAELERACGGRLGVAGFHTGSGARL-QHRAHERFPLCSTFKLVLAAAVLERSA +TDASLLGRRISVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP +AAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPAAMSETVQRLALGDALGAPQRE +QMREWLLGNTTSTERFLAGVPKGWRVGDKTGAGSYGSTNDVGVLWPPSGAPLVLSVYLTF +PDKDAKNRNDVVAEATRIAVR-- +>[subseq from] Beta-lactamase n=1 Tax=bacterium RRLBTPL III-2 TaxID=342580 RepID=Q3S2W9_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGLSLIKHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI0007CC169B +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGSRGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium yuanmingense TaxID=108015 RepID=UPI0012FB4DBD +--RLLEAIRQLESKSSGRLGVTVLDTQTGVSI-HHRGDERFPMCSTFKVLASAAILKRLG +DKLDGLDRRVRIEQSDIVENSQITREHVGPEMSLRELCEAAITRSDNTAGNLLLRNIGGT +AGLTAFARSLGDDVTRLDRVETELNEAAPGDVRDTTSPNAMAENYRRLVLGNALPPAARE +QLSKWMIANKTGDSRLRAGLPQGWRVGDKTGTGGHGTNNDVAIAWPPQRSALIVAVYLTG +ASVDFSGQNEVIASVGREVGKEf +>[subseq from] class A beta-lactamase n=1 Tax=Rugamonas sp. FT82W TaxID=2692167 RepID=UPI00136D139E +-----ALLAKLEVDSGGRLGVAAMNTADGRRL-LHRADERFPFCSTFKMMLSAAVLAK-- +-GPALLKKRVRYSKADMVTYSPVTEDHIGRGMTVAALCEATIQTSDNTAANLLMKQIGGP +AAVTAFARSIGDMEFRLDRMETELNTALPGDPRDTTTPASMLESLHKLVLGDGLGAAQRK +QLKDWMLGTTTGDTRIRAGVPAGSQVADKTGTGSYGTTNDIGVIWQPGKAPVALVVYFTQ +PGKDDKARSEVIAEATRIVVE-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007E8C4CA +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEYw +>[subseq from] class A beta-lactamase n=1 Tax=Curvibacter lanceolatus TaxID=86182 RepID=UPI0003A8CB0A +-----GQWQALERESQGRLGVAVFDTQSGAWL-GHRLDERFAMCSTFKWLAAAQVLRRVD +QGLERLDRRIEFGREALLPWSPVTEKHAGGAMTVGELCHAAITVSDNAAANLLLRSFGGP +EGLTRFARQLGDPVTRLDRWEPELNEAIPGDPRDTSSPRAMVELLRQAVLGPALSVGSRQ +QLAQWLQATQTNVKRLAAGLPASWRVGSKTGTGAHGSTNDVGLYWPPDRGPIVVAVFLTE +SKASLEAREAVLAQVARRV---- +>[subseq from] Beta-lactamase SHV-8 n=1 Tax=Escherichia coli TaxID=562 RepID=BLA8_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARNTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella TaxID=160674 RepID=UPI000597F839 +heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD +AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAGLCAAAITLSDNTAANLLLASVGGP +QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPLAMAKTLRNLLTGSVLSAASRQ +QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMDERNRQIAEIGETLVKHw +>[subseq from] Beta-lactamase n=9 Tax=Bacteria TaxID=2 RepID=A0A141RKP3_9BACT +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A5HJU3_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERDRQIAEIGASLIKHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DFFA30F +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSSFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Enterococcus faecalis TaxID=1351 RepID=A3FFR6_ENTFL +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGKRGARGIVALLGPNNKAERIVVIYLRD +SPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=4 Tax=Bacteria TaxID=2 RepID=Q5DUJ2_KLEOX +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=G3KE69_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNNGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGA------ +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella michiganensis TaxID=1134687 RepID=UPI00136BF30D +--AIQQKLADLEKRSGGRLGVALINTADNSHT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPIAEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella michiganensis TaxID=1134687 RepID=UPI001389BD67 +--AIQQKLADLEKRSGGRLGVALINTADNSHT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPIAEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E3E2061 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYHQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTNQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL73_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAXIGASLI--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1W6ALA0_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAXIGASLI--- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007D70EB2 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQISDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTE8_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPHNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Paenibacillus alvei TaxID=44250 RepID=A0A383RBG2_PAEAL +-nQVHQQFVQLEKKYDARLGVYAIDTGTNQSI-TYRSNERFAYASTFKALAAGVLLQQNS +--IKQLDKVITYTKDDLVEYSPVTEKHVDTGMTLGELAEAAVRSSDNTAANLFLKELDGP +KGFEKALRQIGDQVTHADRFETELNEAAPGDIRDTSTPQALADDLKALTVGNALPPDKRK +LLTDWMRGNATGDKLIRAGVPKDWEVADKSGAGGYGTRNDIAIVWPPNRAPIIIAVLSSR +DKKDAAYQNELIAEAAKVTMK-- +>[subseq from] Beta-lactamase n=11 Tax=Enterobacteriaceae TaxID=543 RepID=A0A0B4U9F2_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRGEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A extended-spectrum beta-lactamase TEM-8 n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI000016F834 +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD8401A +-dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD +RGKEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +DGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRK +QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE +AKAPLDDLNPVFADIGRIVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000418F11C +-dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD +RGKEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +DGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRK +QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE +AKAPLDDLNPVFADIGRIVAD-- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A377TVL0_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPHNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=S6CQJ5_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGEQGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD7F06B +-dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGKEVLLPHSPVTEKHVGGSMTVAELCEAAITISDNAAGNLLLESFGGP +DGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRQ +QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE +AKAPLDDLNPVFADIGRIVAD-- +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005DD5755 +--SLDKQLAALEHSANGRLGIAMINSGAGTKI-LYRGAQRFPFCSTFKFMLAAAVLDQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLARGMTVSELCAATIQYSDNTAANLLIKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALRPAQRS +QLAAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATQIILS-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6B9AJR6_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtARRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Photorhabdus heterorhabditis TaxID=880156 RepID=UPI0006C59345 +--SLHKQLAELENSAKGRLGVTLINTVNGQAI-QYRGDERFPFCSTFKLIVAAAVLHKSM +SQSDLLAKHINYSEVDLLSYAPIARKHLDQGMSITQLCAATLQYSDNTAANLLIKELGGV +AAINHFTQSLGDHTFRLDRWEPDLNSAIPDDPRDTTTPAAMAASVNKIAFGAVLAASQRD +QLIDWLKGNTTGDASIRAGAPAGWVVGDKTGGGDYGTTNDVAILWPPKGAPVILAVYFTQ +FQQDAESRRDVLASATRLVMEH- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=F6MFV3_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Phyllobacterium sp. CL33Tsu TaxID=1798191 RepID=UPI000B81EF52 +--DLDAAFKGLEEKTGARLGVAALDTASDSKI-EYRAHERFAMCSTFKFLAAAAVLAKVD +RKEEKLDRVIKYGKGDLVAGSPATGKHVDEGMTLAALCEAAITLSDNTAGNLLLDNLGGP +KGLTQYARSLGDATFRLDRRETELNEAAPGDPRDTITPAHILKDLQKTVLGNALAKSSRD +QLIEWLLANKTGDKRLRGGLPKGWSVGDKTGTSDSGMANDIAVIWPPSRKPILLAVYLYD +PKGTADSRNEIHRKVASLVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Jiella sp. 40Bstr34 TaxID=2696469 RepID=UPI0013BC71B9 +---VTTAIAKAESELGARVGAMIVDTRSGKTW-SVRAQERFPLNSTFKAFACAAVLGGVD +AGEAALDQQITFTADDLVTYSPVTETRIETGMTLGEVCDAAMTMSDNTAGNLVIESLGGP +DGVTRFMRQIGDAETRLDRTEPTLNEATPGDPRDTTTPEAAARSLEKLVLGDALSPKSRR +QLERWLVGNKVGDPLLRAGFPKSWKVADRTGAGGHGSRSIVAVAWPPERRPIVAAIYLTG +TEASMEARSAAIADIGKAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Collimonas arenae TaxID=279058 RepID=A0A127QL76_9BURK +---FVKKMRQIEAQSGGRLGVAILDTQTGLAH-SYRGDERFPMCSTFKLLAAGFTLKRVD +LGQEQLTRRIRFNAADLMSYSPVTEKHVGGDMSVAELCEAAITLSDNTAANLLLHSFGGP +SLLTAYLRSLDDKVTRLDRIEPDLNESTPGDPRDTTSPKAMLSTMRQLVLGTALAPGSRE +QLTNWLLANKTGDKRLRALLPSGWRVADKTGSGSHGSTNDIGVLFPPNRAPVLVASYLTG +TKANAATREVALAEVGHLT---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. M1 TaxID=2035453 RepID=UPI000BE7DE50 +--NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPAAMLDTLGNLTLGSVLTEASCN +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATVPAKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6Z9I3_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVAAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAACIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000659D03E +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAGLIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=G1EC65_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYSQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Class A beta-lactamase n=1 Tax=Reyranella sp. TaxID=1929291 RepID=A0A521QLV9_9PROT +--DATVKFAELERRNGGRLGVAAFDSASGRRI-GYRGEERFPMCSTFKFLASAFALARVD +RGEERLDRRIVYSAQDLVTYSPITKDHVGPALSVAELCDATMTLSDNTAGNLLLASFGGP +AGLTAYARSLGDQTTRLDRIETALNEGLPGDPRDTTSPVAMLGTMQRLLLGDALSAASRE +RLTGWLLANKTGDKRLRAGMP-GWKVGDKTGTGGNGSANDIAIVWPTGRAPLLVTVYYTG +STISDEARNDVIAEAGRIVA--- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A0M4G455_KLEOX +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium valentinum TaxID=1518501 RepID=UPI0009E77C19 +--RLIGEIKRLESESGGRLGVCVLETATGTRH-VHRGDERFPMCSTFKALAAAAILARVD +AGNEQLTRRITFDASALVVNSPVTEKRVGGDMTVAEICDAAVTRSDNTAGNLLLAGIGGP +SGLTAFARSLGDEVTRLDRDEPSLNEALPGDPRDTTTPNAMASNLQALILGKALSAASRE +QLTAWLIANKTGDTRLRAGFAKGWRVGDKTGTGGRGTNNHVAVVWPPSAAPMVIAVYLTG +ATVSFEQQNAIVASVARAVS--- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A6B3K0A9_RHILE +--NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKVLAAAFVLARAD +KGEESFDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter amalonaticus TaxID=35703 RepID=A0A2U4DMF8_CITAM +--QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE +TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAAALQYSDNTAMNKLLEHLGGT +RSVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA +QLVEWLKGNTTGGQSIRAGLPESWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ +PQQDAKGRKDILAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7HZS0_KLEPN +-----EQIKQSEGQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0012B6975F +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVXRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000447071A +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKQLADGMTVGELCAAAITVSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000C1F7365 +--ETLVKVKDAEDQLGARVGYIEMDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRGEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0013B70E9D +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPAKELNPLFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=2 Tax=root TaxID=1 RepID=A4LAC3_ACIHA +--KTLVKVKDAENQLGARVGYIELDLNSGKILeSFRPEKRFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQSDVVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Class A beta-lactamase n=1 Tax=Cereibacter changlensis TaxID=402884 RepID=A0A4U0Z3Q0_9RHOB +-----SAFKALEEQGGGRLGVAVLDTETGDTS-FWRGDERFAMASSFKAPLCGAVLARVD +AGDEQLDRPIPISADDLIPYAPTVEKHIGGSLTVAQLCEATITLSDNVAANLLLDTLGGP +SGLTAFLRSIGDDVTRLDRFEPELNEATLGDPRDTTTPRAMADTLNSLLLGGVLSVESRT +QLADWLKANQTGDDRIRAGLPEGWQIGDKTGTSGTGTFADIAILYPPQGKPILMAVYLAE +TDVSTKEANGVHAGVAQLVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE36E2D +--DLAAAFKTLEERTGARLGVAAHDTGSDNRI-GYREDERFAMCSTFKFLAAAAVLARVD +REEEELNRIVKFKKSDLVDYSPVTEKHLDSGMSLAAICEAAVTMSDNTAGNLMLDNIGGP +KGLTEYARRLGDATFRLDRRETDLNEAKPGDPRDTITPIAILKDLQKTAIGDALGKSSRD +QLIEWLLGSKTGDKRLRAGLPKDWSVGDKTGTSDSGMANDIAVIWPPERKPILLAVYLYD +PKGTPDSRNEIHQKVAKLVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Sorangium cellulosum TaxID=56 RepID=UPI000CF40EB1 +---AAPALARVEAQLGGRLGVAALDTATGARV-GHRAAERFAMCSTFKALLAASLLARVD +QGKLTLDRRVTYRASDLLEHAPVTRAHLAEGLTVEELCAAAVEISDNTAANLLLAQIGGP +AGLTAYIRSLGDQVTRFDRNEPTLNTNVPGDPRDTTSPDAMTDTIRVLLVGDALSEASRA +RLKSWMVRSTTGLARLRAGLPKDWVVGDKTGTGENGAANDVAVAWPPSRAPIVIACFVDA +PSASVDARNAAHAEAARIVAEVf +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Mycoplasma mycoides TaxID=2102 RepID=UPI001019DE04 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGXVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Class A beta-lactamase n=1 Tax=Rahnella inusitata TaxID=58169 RepID=A0A419M6P6_9GAMM +-kAVQQKLADLEKSTGGRLGVAMINTADNSQT-VYRGEERFAMCSTSKVMAASGVLKASE +QDKNLLNKHVDIKKSDLVNYNPITEKHLDTGMTLGELGAAAIEYSDNVAMNKLIAQLGGP +AKVTQFARSIGDETFRLDRTEPTLNTAIPGDKRDTTSPLAMAQSLRKLALGDALAEPQRA +QLVAWLKGNTTGAASIRAGLPASWTVGDKTGSGDYGTTNDIAVVWPDNHAPLILVTYFTQ +PQQDAKARKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=G1JY45_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRGEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERDRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2R8G1S5_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEESFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1W6AL88_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKH- +>[subseq from] Uncharacterized protein (Fragment) n=2 Tax=marine sediment metagenome TaxID=412755 RepID=X1IDJ4_9ZZZZ +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKH- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00129DA628 +-----EQIKLSESQLSGRVGMIEMDLTSGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=Q5DUI8_KLEOX +--AIQQKLANLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium tarhaniae TaxID=1187852 RepID=A0A0J6T156_9RHIZ +--DAAARLAQLERRDGGRLGVEVRDTATGRRF-GHRADERFPMCSTFKALAAAAVLARAD +TGKDDLNRRITYGRDAVLSYAPVTAKHVETGMTLAELCAAAVVWSDNTAANLMLDTLGGP +GGITAFAHAHGDTVTRLDRTEPTLNTAIPGDPRDTTSPAAMVGLLDNVLLGQALTDKSRA +RLAGWMNESPTGLKRVRAGLPEGWRVADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG +SPAEPAARDALHAEVGRLIARSf +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2D95B9 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWEKELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium yanglingense TaxID=61013 RepID=A0A245Z7K2_9RHIZ +-dDIERRLAELENRTGGRLGVSVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD +KGEENLERRVIYDQDKLVSYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLLLESVGGP +KALTKWLRSIGDRATRLDRWETALNEGKKGDPRDTTTPDAMLDTLGNLALGSVLSEPSRE +KLIEWMLANTTGDARLRAGLPGAWKVGDKTGTGDNGTAADIAIIWPKGRGPILVTAYIAE +ATAPVKELNLVFAEVAKIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTA8_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPADWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] BETA-LACTAMASE TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000011206D +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDATAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0013EF5EFB +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIAKIGAALIEHw +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0000D579BD +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVYNSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q840S0_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTIGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Terriglobus albidus TaxID=1592106 RepID=A0A5B9EF56_9BACT +------FLAQLEKEKGGRLGVSVLDTQTGAHA-GHRAGEAFPMCSTFKLSLAAQVLARVD +HGEEKLDRLVTYTQADLLSYAPVTKEHVATGMTVGALCEAAITLSDNTAANLLLVTVGGP +AGFTRWLRSLGDTATRLDRNEPTLNSAEPGDQRDTTTPSAMLATLQKLTLGNVLSPASRK +QLNDWMLATQTGLKKIKAGLPADWKEGDKTGSGDNSTTNDIAVLYPPDRKPVLITVYYTG +SKLETDQSNLVFQEIGRK----- +>[subseq from] Beta-lactamase n=2 Tax=Variovorax sp. OV700 TaxID=1882826 RepID=A0A1G8KY70_9BURK +--SAEAQLAALESSVGGRLGVAAFDTATGARV-QHRATERFPLCSTFKTMLAAAILERSA +RDSALLERRVSYGKSDILPHSPITEKYLEQGMAVSAMCAATIQYSDNAAANLLMKILGGP +SAVTAFARSIGDQAFRLDRWETELNSAIPGDPRDTTTPEAMAASLQRLVLGDGLGATQRG +QLQNWLLGNTTGATRIRAGVPADWKVGDKTGAGSYGTVNDTGVLWPPVGAPLVLAVYLTF +PTKDAEGRNDVIASAARIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A485UQB8_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3S4T2_KLEPN +-----EQIKLSESQLSGRVGMIEMDLTSGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rubeoparvulum massiliense TaxID=1631346 RepID=UPI0009757614 +--ETSRKFMQLEKEFDVRLGVYAIDTSTNRTV-AYRPDERFAYTSTFKVLAAGAVLQQNS +--IDKLDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLQKLGGP +NGFEKALRQIDDNVTEADRFEIDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPNDKRT +ILTDWMRENTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPNRDPIIIAILSTR +DTKNATYNNELIAKAAKVALNAf +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DE6D769 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRFAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B7FDD8_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVGYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D3AD2AA +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERLPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0006459C33 +-----EQIKLSESQLSGRVGMIEMDLTSGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010327675 +--NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8RMG3_ECOLX +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIVEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A089MWI9_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALID-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=A0A292CDR2_PROVU +-nTVEEQLNTLEKYSQGRLGVALINTEDNSQI-IYRGEERFAMASTSKVMAVAAVLKASE +KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLGGP +AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEQDAKYRKDIIAKAAEIVTK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus glycinifermentans TaxID=1664069 RepID=A0A1C3SFF6_9BACI +-----NQFSRLEDQYDARLGVFALDTGTNKTV-AYRADERFAYASTHKALAVGALLQQKS +--IADLNQRITYTRDDLVNYNPITEKHVDTGMTLKELCDASIRYSDNTAGNLILKQIGGP +SGFKQSLREIGDNVTNPERIEPDLNEVKPGETHDTSTPKALAKSLQAFTIGDALPKEKRE +MLVDWLKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPKGDPIVLAVLSSR +DKKDADYNDKLIAEVAKEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0003FC61A4 +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGKKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTLPVKELNPIFAEVGRMVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas mosselii TaxID=78327 RepID=UPI00048EDF1A +hdPLRQAMQQLEAASGSTIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHRNE +AEPGLLARRIAYGAEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP +PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLTDGLPAAAQQ +QLQAWLKGNTTGDARIRAGLPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG +TKQDAPWNSETIAAATRVVVEAw +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas mosselii TaxID=78327 RepID=UPI00083DE284 +hdPLRQAMQQLEAASGSTIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHRNE +AEPGLLARRIAYGAEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP +PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLTDGLPAAAQQ +QLQAWLKGNTTGDARIRAGLPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG +TKQDAPWNSETIAAATRVVVEAw +>[subseq from] Beta-lactamase n=6 Tax=Gammaproteobacteria TaxID=1236 RepID=Q8KRG7_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0009C44BE8 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Collimonas arenae TaxID=279058 RepID=UPI0007782166 +---FVKKMRQIEAQSGGRLGVAILDTQTGLAH-SYRGDERFPMCSTFKLLAAGFTLKRVD +LGQEQLTRRIRFNAADLMSYSPVTEKHVGGDMSVAELCEAAITLSDNTAANLLLHSFGGP +SLLTAYLRSLDDKVTRLDRIEPDLNESTPGDPRDTTSPKAMLSTMRQLVLGTALAPGSRE +QLTNWLLANKTGDKRLRALLPSGWRVADKTGSGSHGSTNDIGVLFPPNRAPVLVASYLTG +TKANAATREVALAEVGHLT---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YE79_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEMHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ESJ9_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIE-- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus delbrueckii subsp. bulgaricus TaxID=1585 RepID=A0A5C7G8U0_LACDE +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGECGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=A0A5N8G2N8_9ENTR +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A6B8MHP4_KLEOX +--TIQQKLAELEKSSGGRLGVALINTADNSQT-LYRGNERFAMCSTGKVMAAAAVLKESE +NNKDVVNKRLEIKESDLVVWSPISEKHLKNGMTLAELSAATLQYSDNTAMNKIIGYLGGP +DNVTAFARSIGDTTFRLDRTEPTLNTAIPGDERDTTTPQAMAESLQKLTLGNALGEQQRA +RLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENQAPLVLVTYFTQ +PQQDAKNRKDVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=A0A2Z3EW51_9ENTR +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDERLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] Class A beta-lactamase n=1 Tax=Enterobacteriaceae bacterium ML5 TaxID=2507584 RepID=A0A4S3LL16_9ENTR +-kAVQQKLAELEKSTGGRLGVAMIDTASNTQT-LYRADERFAMCSTSKVMAASGILKASE +TDKNLLNKHVDIKKADLVNYNPITEKHLDSGMTLGELGAAAIQYSDNVAMNKLIAQLGGP +AKVTQFARSLGDETFRLDRTEPSLNTAIPGDKRDTTSPLAMAESLRKLTLGNALAEPQRA +QLVEWLKGNTTGAASIRAGLPATWQVGDKTGSGDYGTTNDIAVIWPDNHAPLILVTYFTQ +PQQDAKARKDVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=UPI00005F9E03 +--SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLAAAVLGRSQ +SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL +AMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRE +QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVVYFTQ +LKKEAEPRRDVLAAATKIVLAH- +>[subseq from] Beta-lactamase n=1 Tax=Solimonas aquatica TaxID=489703 RepID=A0A1H9I0M1_9GAMM +--ALLTQLGQIEQSVNGRLGVAIEDSHSGRRW-QYRGDERFPMCSTFKLLACAALLARVD +AGLAQLQQLQAYGEDELVRYSPVTQDYAGKGLSWAQLCEAALTRSDNTAGNLILRAIGGP +AGLTAFARSLGDALTRLDRWETELNEARPGDPRDSTTPLAMNANLRTLLLGERLKPASRE +QLIAWLLANQTGDARLRAGLPRDWRVGDKTGAGEQGTNNDIAIAWPPQRAPLLISVYLTQ +SPASFEARNQALAAVAQALVRH- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium phaseoli TaxID=396 RepID=UPI0007EB8FCB +--NVERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAASFALARVD +KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +KLIAWLVASTTGKERLRAGLPADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPMKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) TaxID=393305 RepID=UPI0006DBD7C2 +--SLDKQLAALEHSANGRLGIAMINSGAGTKI-LYRGAQRFPFCSTFKFMLAAAVLDQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLACGMTVSELCAATIQYSDNTAANLLIKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALRPAQRS +QLAAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATQIILS-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDA824A +-dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +QGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRK +QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE +AKAPLDDLNPVFADIGRIVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia aspalathi TaxID=1324617 RepID=A0A1I7E7D4_9BURK +--AIRQRLAQIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKLLAAGFVLTRVD +RGQEDLERRIVFSKSDLVPYSPATSQHTRERMSVADLCKAAITLSDNTAANLLLASFGGP +AALTAFARSIGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELLLGERLSSPSRA +QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVTVYLTE +TSGDAARSNAAIANVGALIV--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RHY2_9BACT +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPPSWGVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2B6427 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIHLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YPN9_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKCE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRVPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E0962C4 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKLVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A125R6L3_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMTDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B2EE39 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKDLTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK +DEKEAAYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Photorhabdus heterorhabditis TaxID=880156 RepID=A0A5B0VHH5_9GAMM +--SLHKQLAELESSAKGRLGVTLINTVNGQAI-QYRGDERFPFCSTFKLIVAAAVLHKSM +SQSDLLAKHINYSEVDLLSYAPIARKHLDQGMSITQLCAATLQYSDNTAANLLIKELGGV +AAINHFTQSLGDHTFRLDRWEPDLNSAIPDDPRDTTTPAAMAASVNKIAFGAVLAASQRD +QLIDWLKGNTTGDASIRAGAPAGWVVGDKTGGGDYGTTNDVAILWPPKGAPVILVVYFTQ +FQQDAESRRDVLASATRLVMEH- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHZ2_KLEPN +-----EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDERLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKRVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIAKIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia plantarii TaxID=41899 RepID=UPI0008707720 +-----RQLAALDGSFDGRIGVAALDTGSGARL-LHRADERFAFCSTFKTILVSALLTRAA +GDPRLLSSVIRYRAQDLVRYSPVSEKHVDTGMSVAGLCAAALQYSDNSAANLLIRMVGGP +AAVTAYARSIGDRRFRLDRIETELNDAVPGDERDTTTPAAMLDTLRRVTLGDALDASGRA +RLISWMLGNTTGDARIRAGVPAGWRVADKTGSGDYGSANDVAVIYPPRRAPIVLVVYTTR +DRKDAEYDNAAIASAARIVTAAf +>[subseq from] Beta-lactamase n=1 Tax=Jiella endophytica TaxID=2558362 RepID=A0A4Y8RIS9_9RHIZ +-----RAVEKAGSDLGARVGVMIVDTQSGKVW-SARADERFPLNSTFKAFGCAAVLGQVD +AGEASLNETITYSADDLVTYSPVTEKHVDTGMTLGEICDAAMSMSDNTAGNLVIESLGGP +DGVTQFMRAIGDGETRLDRTEPTLNEAAPGDPRDTTTPKAAAASLQTLVLGDALSETSRQ +QLKSWLIGNKVGDPLLRAGFPKDWAVADRTGAGGHGSRSVIAVAWPPERKPIVAAIYLTG +TEASMEARSAAIAEIGKAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum hiltneri TaxID=341045 RepID=UPI00069E976B +---VVSRLAKLEASVAGRLGVEILDSGTGRRW-GYRADERFPMCSTFKFLAASAVLRRVD +TGAEQLDRRIVYGEDVLVNYSPTTSKHVGGDLSLAQLCEAAITLSDNTAANLILHSLGGL +GPFNKFVRSLGDDTTRLDRFETELNTSIPGDPRDTTTPTAMTGNLQKVLLGDALSAASRR +QITAWMLANKTGDRRVRAGMQPGWKVGDKTGSGDYGTTNTVAIIWPPQGAPLLASIYLTE +TRAPEEQRNAVLAEVGKLIV--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A385FUJ6_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDARVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium azibense TaxID=1136135 RepID=A0A4R8A9G7_9RHIZ +-dDIERRLAELEKRTGGRLGVSVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD +KGEENLERRVIYDQDKLVSYSPETEKHVGGEMSVGELCKAAITLSDNTAGNLLLESVGGP +KALTKWLRSIGDRASRLDRWETALNEGKKGDPRDTTTPDAMLDTLGNLALGSVLSEPSRE +KLIEWMLANTTGNARLRAGLPGAWKVGDKTGTGDNGTAADIAIIWPKGRGPILVTAYIAE +ATAPVKELNPVFAEVAKIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=R4S350_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVDGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium gallicum bv. gallicum R602 TaxID=1418105 RepID=A0A0B4X006_9RHIZ +-dDIERRLAELEKRTGGRLGVSVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD +KGEENLERRVIYDQDKLVSYSPETEKHVGGEMSVGELCKAAITLSDNTAGNLLLESVGGP +KALTKWLRSIGDRASRLDRWETALNEGKKGDPRDTTTPDAMLDTLGNLALGSVLSEPSRE +KLIEWMLANTTGNARLRAGLPGAWKVGDKTGTGDNGTAADIAIIWPKGRGPILVTAYIAE +ATAPVKELNPVFAEVAKIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium tropici TaxID=398 RepID=UPI000648C5F0 +-dDIQHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGEEKLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPEAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +AAAPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0005CDCEBC +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRYYGELNEAIPNDERDTTMPAAMATTLRKLLTGELLTPASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1W6AL65_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAXIGASLIKH- +>[subseq from] class A beta-lactamase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=UPI000CCBF5F2 +--TLDQQFKQLENDFGARLGVYALDTATGLTI-RYREDERFAYASTSKALAVGAVLAQSP +--VEELDKRITYTSDDLVSYSPITKDHVGKGMTIRELCDAAVRYSDNTAANLLFKELGGP +EGFAKVLKEIGDDVTNPVRIEPDLNEATPGDLRDTSTPKALATSLQAFTLGEVLSADKRS +ILINWMKENTTGDELIRAGAPTGWVVGDKSGAGSFGTRNDIAVVWPPDRAPVVISILSSR +DTKDAKYDNALIAQAAKIALD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0E3GM50_PSEAI +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMVATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000E2B5688 +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRANERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=A0A209APQ5_YERFR +-eSLDKQLAELERKSNGLLGIAMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHIKYHESDLLSYAPITRKNLAQGMSVSELCAATIQYSDNTAANLLIKELGGI +AAVNEFARSIGDHTFRLDRLEPDLNTALPNDPRDTTTPAAMAASLNKLVLGDALPAAQRE +QLAIWLKGNTTGGETICAGAPADWIVGDKTGGGDYGTTNDIAVLWPPTGAPIILVIYFTQ +REKDAKPRRDVLAEATKMVLSH- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010344399 +-----EQIKLSESQLSGRVGMIEMDLSSGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGEQGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q5DUJ0_KLEOX +--AIQQKLADLEKRSGGRLGVALINTTDDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTD5_KLEPN +-----EQIKLSESQLSGRVGMIGMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Superficieibacter electus TaxID=2022662 RepID=A0A2P5GGS6_9ENTR +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQLAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium symbiodeficiens TaxID=1404367 RepID=UPI00140FDC25 +-----EAIKQLELKSGGRLGVSVLDTMTGVPI-HHKGDERFPMCSTFKVLAAAAILKAAG +SKLEALERRVRIEQADLVEYSPVTREHIGGKMTLRELCDAAITRSDNTAGNALLKNIGGP +AGLTSFARSIGDDITRLDRTETGLNEAKPGDPRDTTTPNAMAANYRRLLLGDVLLPEGRD +QLGQWLIANKTGDTRLRAGLPQGWRVGDKTGAGENGTANDVAIVWPPKRSPLIIAVYLTG +ASLDPNGRNDVIASVGREVGKAf +>[subseq from] Beta-lactamase n=1 Tax=Thalassospira sp. KO164 TaxID=1798192 RepID=A0A1B9VH43_9PROT +--RLLDAVQTVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAVLHKVD +RESETLDRRITYRSDDLVTYSPITEKHVDSGMTIGELCEAALHLSDNTAANLVLDVLGGP +DVLTAYLRDIGDDVTRLDRIEPDLNAATPGDARDTTTPNAMRATLTYLLLGDALSLESRQ +ILEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPERKPVIVAIYITQ +TSASMEERNAAIADLGQEIA--- +>[subseq from] Beta-lactamase n=1 Tax=Cobetia crustatorum TaxID=553385 RepID=A0A558HM76_9GAMM +----QEALRAIEKKVDARIGVTVLDTADGSRF-SYRGDERFPMSSTFKALACGSLLALVD +DKQESLQRKVKIMPDDVVTYSPVTETQTEGDMTLSELCSATITTSDNTAGNLILAALGGP +QGLTGYLRSLGDEKTRLDRTETALNEATPGDVRDTTTPTAMVMTLEKLLLGDALSETSRL +KLQGWLLANTTGDDKLRAALPADWQIGDKTGGGGYGTNNDIAIIWPPGNAPLIVAVYLTK +STASIAERNAAIADIGRLLVS-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Campylobacter hepaticus TaxID=1813019 RepID=UPI00104EC8C8 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNXERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHZ5_KLEPN +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIAKIGAALIEHw +>[subseq from] Beta-lactamase protein n=2 Tax=Rhizobium TaxID=379 RepID=B3PTM9_RHIE6 +--NVERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD +KGDESLDRRVTYGKEKLVDYSPISEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +KLIAWLVASTTGKERLRAGLPADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATTPAKDLNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=2 Tax=Leptolyngbya sp. NIES-2104 TaxID=1552121 RepID=A0A0N7Z4R7_9CYAN +--SAQTQFAKLERTLAGRLGVFALNTANRAQL-SYRANEPFPLCSTFKILLTSAILKRST +QVEGLMQQRIRYQQRDLVTYSPITEQHVKEGMTVAALCAAAMQYSDNTASNLLMKILGGP +GSVTAFARSIGDRQFRLDRWETALNSSIPGDRRDTSTPAAMGLSLQQLALGNALEPHLQA +QLQAWLRGNTTGAARIRAGVPANWQVGDKTGTGDYGTANDVAVLWSPQRSPVVVAIYTTQ +GEKDAKARNDIIASAARIVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A0M4FM41_KLEOX +--TIQQKLADLEKSSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium anhuiense TaxID=1184720 RepID=UPI000BE8A457 +-dDIQHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGEEKLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPEAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVTELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B7FDE1_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKAGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas graminis TaxID=158627 RepID=A0A4R7W6G9_9PSED +---IQQQLADLERRHGGRLGVAILDTASQRLI-SHRGDERFALCSTFKCLAAAHVLARVD +QKQEDLSRRIVYSAEQLVAYSPTTELHVGGQLSVGSLCEAAMTLSDNTAANLLLDSMGGP +DGLTAWLRSIGDTQTRLDRREPDLNENRPGDLRDTTTPVAMLQTLNTLVLGDELRLASRD +QLTAWLVNNQTGDKKLRAGIPGGWRVGDKTGSGANNASNDVAVIWPGDRPPILVTVYYTG +SKASGDQSNALMADIGRLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Yersinia kristensenii TaxID=28152 RepID=A0A0T9T9C2_YERKR +--SLDNQLAELERTANGRLGVALINTANGSKV-QYRGGQRFPFCSTFKLMLTAAVLGQSQ +SLLGLLDKHIRYHESDLLSYAPITRKNLAQGMTVSQLCAATIQYSDNTAANLLIKELGGL +EAINQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASIHKLVLGEALKTPQRE +QLVVWLKGNTTGDATIRAGVPTDWIVGDKTGSGDYGTTNDVAVIWPSQGAPLVLVLYFTQ +RQKDAESRRDVLASATKIVLSH- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=A0A6A7ZWF0_RHIML +-dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +DGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRK +QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE +AKAPLDDLNPVFADIGRIVAD-- +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0005CDCEC6 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRYYGELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia azotifigens TaxID=2057004 RepID=A0A5C6VQB2_9BURK +--AFKKQLAQIEAQVGGRLGVAILDTASGKQH-GWRMNERFPMCSTFKVLLASAVLTRKD +QGKEELGRKVVYAKDVVVANSPVSGPRAGGDMTVSELCEAAITRSDNTAANLLLESIGGP +AALTAFVRGMGDKVTRLDRNEPTLNEALDGDPRDTTTPAAMLADLRALLLGEHLSAASRE +QLTAWLVANKTGDARLRAGLPKDARVGDKTGTGERGTSNDIAIVWPAGRPPILVTVYLTG +ATASAAQRDAAIAKVGALAAQ-- +>[subseq from] Beta-lactamase n=2 Tax=Rhizobium TaxID=379 RepID=A0A3S0QDQ6_9RHIZ +-dDIQHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGEEKLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGATRLDRTEPTLNEGKKGDPRDTTTPEAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGPNGTLGDIAVIWPPDRGPIVAAVYIAE +ATAPVTELNPVFAEVGRMIVE-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000E2A5B02 +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRN +TPATMAERNQQIAKIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=B8R7R2_9BACT +--TLAAQLSALEASANGRLGVALIDSGSSRQL-SYRGEERFAMASTFKALAAAAVLQRSV +EQPALLNKRIIYQQSELITYSPVTEKHLQQGMTVAELCAAAVELSDNTAGNILLREIGGP +QGITQLARRLGDNQTRLDRREPALNSAIPGDVRDTSTPLAMAGNLNQLALGKALPSAQQQ +LLIQWLKQSKTGAQSIRAGVPQGWQVGDKTGAGGYGTTNDLAILWPPQGKPLVLAVYFTQ +HNPQAEARRDVLASATRLVLAAw +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI000D654FC1 +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKADLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP +EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella huaxiensis TaxID=2153354 RepID=A0A564GUD4_9ENTR +--AIQRKLTDLEKSSGGRLGVALINTTDNSQI-LYRGDERFAMCSTGKVMAAAAVLKQSE +ADNQVLNKRLEIKKSDLVVWSPVTEKHLQSGMTLAELSAATLQYSDNTAMNKMIGYLGGP +DKVTAFARSIDDVTFRLDRTEPALNTAIPGDERDTTTPLAMAESLHKLTLGNALGEQQRA +QLVTWLKGNTTGGQSISAGLPAGWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=2 Tax=Caballeronia sordidicola TaxID=196367 RepID=A0A242N2B9_9BURK +--KISKRLARIEASTSGRLGVSVLDTGSGAHA-GLRADEAFPMCSTFKFLAAGFVLARVD +KGEEDLKRKIVYSKSDLVDYSPVTQHHADSALSVAALCDAAITLSDNTAANLLLASFGGP +AALTAFVRTLGDTQTRLDRNEPTLNESTPGDPRDTTTPNAMLANMRTLLLTDRLSVSSCA +QLRDWLIANKTGAKRIREKLPKDWRVGDKTGTGSHGSTNDIAIIWPPKRAPLLVTAYLTL +TSAQTARREAAIADIGGLVVSSf +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=F8TCS6_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMISTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLAIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q0PGR7_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMISTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLAIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3LUK8_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWCADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005DC22EA +--SLDKQLAALEHSANGRLGIAMINTANGTKI-LYRGAQRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLVKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDASIRTGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATKIILS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q6R7N4_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIAEKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A120HUS1_ACIBA +--ETLVKVKDAEDXLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGAS----- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDBBC84 +-dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD +RGKEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESLGGP +QGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGLVLSQEGRK +RLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE +AKAPLDDLNPVFADIGRIVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. DHOC27 TaxID=2303330 RepID=A0A372K7X0_9BURK +-----ARFAQLEGTFGGRLGVYALDTGNGARI-MYRESERFPFCSTFKVILAGAILTMSE +RNEGLLKRRIKYSQKEVVHYSPISEKHVADGMTIEELCRAALQYSDNTAANMLIAQAGGP +SGVTSFAHSIGVDEFRLDRWETALNDAIPGDPRDTATPAAMAHALQVLTLGDALPAALRE +TLQTWLRGNTTGTKRIAAGVPAGWQVGDKTGTGDYGTGNDLAILWPPGRKPVILAVYHTN +SDANAQPNDQVIAEAAKIVAA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Paraburkholderia sp. BL10I2N1 TaxID=1938796 RepID=A0A4R6ERV6_9BURK +--SAQDRLTVLETSSGGRLGVAALSTAGSTQL-DYRANERFAVCSTSKVLIASAILKRSE +KEAGLLEQRIHYTKSDLVAYSPVSERHMDSGMTVAELCAAALDYSDNTSANLLMKLLGGP +SAVTAFARSIGDETFRLDRWETELNSAIPGDLRDTSTPAAMAQSLQRVALGDALAAPQRN +QLQAWLRANTTGSMRIRAGAPADWIVGDKTGTGDFGTTNDIAVLWPPAKPPVIVALYFTQ +REKDAKPRNDVLASAARIVVESf +>[subseq from] class A beta-lactamase n=1 Tax=Proteus cibarius TaxID=626774 RepID=UPI000D68BA63 +-nTIEEQLNTLEKYSQGRLGVALIDTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKASE +KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLGGP +TKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEQDAKYRKDIIVKATEILTKEf +>[subseq from] class A beta-lactamase n=1 Tax=Proteus TaxID=583 RepID=UPI000950CE19 +-nTIEEQLNTLEKYSQGRLGVALIDTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKASE +KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLGGP +TKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEQDAKYRKDIIVKATEILTKEf +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A347VB55_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKDLTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK +DEKEAAYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YPM8_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKSDTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] Beta-lactamase n=2 Tax=Yersinia enterocolitica TaxID=630 RepID=A0A485DJC8_YEREN +--SLDKQLAALEHSANGRLGIAMINSGAGTKI-LYRGAQRFPFCSTFKFMLAAAVLDQSQ +SQPNLLNKHINYHESDLLSYAPITCKNLARGMTVSELCAATIQYSDNTAANLLIKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALRPAQRS +QLAAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATQIILS-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. PDO1-076 TaxID=1125979 RepID=H4EZM6_9RHIZ +--QFAQALEAIEARIQARLGAFVLDTETGTTL-GYRADERFPMCSTFKAIAAAAVLSRVD +AGKEDLSRRLHWKKADLIAHSPVTEKHVKDGLTLTELCHAATTVSDNTAANLMLEAIGGP +SGFTAFVRSVGDPVTRIDRMEPALNSAKPGDKRDTTSPAAMAALLKTLVLDDALSPASRD +QLGQWMVANTTGGTKLRAGLPRGFTVGDRTGAGANGTNNVVAVIWPPQRKPLVATVFITE +TQTPRPETDPAMAEIGRLLT--- +>[subseq from] class A beta-lactamase n=1 Tax=Proteus cibarius TaxID=626774 RepID=UPI00131FB24E +-nTIEEQLNTLEKYSQGRLGVALIDTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKASE +KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLGGP +TKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEQDAKYRKDIIVKATEILTKEf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI001441C409 +--NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q09Q12_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERDRQIAEIGGSLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Methyloceanibacter superfactus TaxID=1774969 RepID=A0A1E3VVX1_9RHIZ +-eALARAFAEIEGHVGGRLGVAVLDTGSGLSA-DLRGDERFPLCSTFKWLAAAALLSRVD +AGTESLGRPIGIRAQDIVTYSPATEKHVGGTMTLGEICAAAITLSDNTAGNLMLGALGGP +EAVTAYARSLGDQTTRLDRTEPTLNDVPPGDPRDTTTPLCMLGDLQAVLVGEALSEASRA +QLIAWLLANTTGETRLRAGLPSTWRVGDKTGTCNANTANDVGIVWPPDRAPILIAAYLAE +TTASREAQNAALADVGRAVAT-- +>[subseq from] Beta-lactamase n=6 Tax=Proteobacteria TaxID=1224 RepID=R4RPE6_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAKRNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Diaphorobacter sp. HDW4B TaxID=2714925 RepID=UPI001408335B +--SVSEPWSRIEKQSTGRMGVAVLDTAHGGWD-GQRLDERFPMCSTFKWLAAAHVLQRVD +QGREQLDRRIRFERKALIDYSPVTEPQAGKNMTLAELCHAAITVSDNTAANLLLETLGGP +QGMTAFARSLGDDVTRLDRWEPDLNESKPGDPRDTTSPRAMATLLQQLVLGDVLSPRSRE +QLVQWMRATSTNRNRLAAGLPQGWKIGSKTGSSGTGSVNDVGVFWPPNRPPIIAAVYVTQ +GTGSTKSIEPAIAAVAQHIT--- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus elgii TaxID=189691 RepID=UPI000C1CA0B1 +-----DEFIQLENKFGARLGVYAIDTGTSRTI-AYRPEERFAFASTYKALAAGAVLQQSS +--IANLDKVITYTKEDLVTYSPITEKHVETGMTLRDICDAAIRYSDNTAGNLLLKELGGP +KGFETVLKKIGDNVTTSARFETDLNQAIPGDTRDTSTPKALATTLQAFTVGDVLPTDKRK +LLTDWLRGNTTGAKLIRAGVPEGWQVGDKTGAGSYGTRNDIAIVWPPNRDPIIIAILSSR +DKQDSAYNDDLIAQAAKITMD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A4U9LAJ1_ECOLX +--------KDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Rhizobium TaxID=379 RepID=A0A654NBN4_9RHIZ +--NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP +AALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLINWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=A0A0T9M378_YERIN +--SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLAAAVLGRSQ +SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL +AMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRE +QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVIYFTQ +LKKEAEPRRDVLAAATKIVLAH- +>[subseq from] Beta-lactamase n=1 Tax=Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) TaxID=393305 RepID=A1JML9_YERE8 +--SLDKQLAALEHSANGRLGIAMINSGAGTKI-LYRGAQRFPFCSTFKFMLAAAVLDQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLACGMTVSELCAATIQYSDNTAANLLIKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALRPAQRS +QLAAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATQIILS-- +>[subseq from] class A beta-lactamase SHV-116 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00042D6680 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWHADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000671E4AF +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERQIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDARVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RE33_9BACT +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIPDKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000EF28063 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTSASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3YA66_KLEPN +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ +QLLQWMLDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIAKIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A291NXZ6_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMVSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLVDGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D620_KLEPN +-----EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=C0LSK2_KLEPN +-----EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A220NZ16_KLEPN +-----EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI001399448B +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITMSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus pacificus TaxID=2026187 RepID=A0A5C4ZJQ8_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKELTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIKEAAEVVVNAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZI86_ECOLX +--DVQQKLAELEWQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000DC7E176 +-----EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPASMAERNQQIARIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000A25DB63 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEPw +>[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. YMA4 TaxID=1593482 RepID=UPI000DD1355C +-----SAFAALERKFKGRVGVAAIDTASGKVI-GNRQDERFPFCSTFKTIVAAAVLARSA +TEPGFLGKRLRYTQADIKPHSPVSEKHVEAGMTAAELCAATIQYSDNAAANILMRELGGP +AAITAYARTLGDTTFRLDRWETELNSAIPGDERDTTTPLAMARTLQKLLVGDGLPPAQRQ +QLKDWMVGNTTGDTRIRAGVPKGAVVADKTGTSGYGVANDMGVIYLPQRAPIVLVVFTHG +ATEQAEARSESVAEATSVALR-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella michiganensis TaxID=1134687 RepID=UPI000FF8CB60 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Herminiimonas sp. KBW02 TaxID=2153363 RepID=A0A3N7A510_9BURK +-qTAQEELKKIEVRSGGRLGVSAINMASDQRV-EYRAEERFPFCSTFKVMVAAAVLQRST +SDTSLLQKRIRYKKEDTEKYAPITQKYLADGMTVSELCAATLQYSDNAAANFLMKELGGP +AAVTAYMRSIGDNVFRLDRWEPELNSALPGDERDTSTPAAMENSLEKLALGRALPQPQRE +QLMNWLKGNTTGGKRMLAGVPGGWQVADKTGTGSYGTTNDIGILLPPGGSALVTAIYFTQ +NGKDAAPREDVIASATRIVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8KRG8_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATFGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000C7AD308 +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDERLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIAKIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00044E93B6 +-----EQIKQSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0R7FDJ3_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTE0_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARMD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Class A beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5RTG7_9BACT +--DAANQIAAIEARLGSRIGVAALDTGSGKRL-DYRAEERFPMCSTFKFLAATAVLKRVD +KKQDRLDRFISYDAKDILEYAPITKAHLKEGMTLGALCEAAIEQSDNTAGNLLLDAIGGP +AGVTNFARSLVDQVTRLDRKEPDLNSAIPGDERDTTTPGSMLADMTRILTGDVLSRSSRR +QLKDWLQRNKTGETMIRAGVPTDWIIGDKTGRGANGATNDIAIMRPPDRAPMLLAIYSLG +STATANDRAAAIAEVAKIVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia aleksiciae TaxID=263819 RepID=UPI001427B427 +--SLDNQLAELERTANGRLGVALINTANGSKV-QYRGGQRFPFCSTFKLMLTAAVLGQSQ +SLLGLLDKHIRYHESDLLSYAPITRKNLAQGMTVSQLCAATIQYSDNTAANLLIKELGGL +EAINQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASIHKLVLGEALKTPQRE +QLVVWLKGNTTGDATIRAGVPTDWIVGDKTGSGDYGTTNDVAVIWPSQGAPLVLVLYFTQ +RQNDAESRRDVLASATKIVLSH- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. M10 TaxID=1324586 RepID=A0A2A6L7R8_9RHIZ +--NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPNAMLDTLGNLTLGSVLTEASCN +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATVPAKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9K582_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDELNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A3FFR2_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGTVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B529681 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=Q9L760_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. FW305-17 TaxID=2070681 RepID=A0A2N8FF90_9PSED +---LRKPLQQLEATTGSTIGLWALDTGSGQQL-AWRAEERFAFCSTFKAVLAGAILHRSQ +AEPGLLERRIAYGAEQLVVYSPVTEKHVGAGMTVAGLCAAAVQYSDNTAGNLLLELVGGP +PGLTAFARSLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLGDGLAAAERQ +QLQAWLKGNTTGDARIRAGVPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG +AKADAPWNSETIAAATRVVVDAw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=UPI00077C9547 +----AHKFMQLEKKFDARLGVYAIDTGTNRTV-AYRPDERFAYSSTFKALAAGLVLQQNS +--LDELDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLEELGGP +DGFENGLRQIGDHVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPDSKRT +ILTDWMRGNTTGDELIRAAVPMGWEVGDKTGAGGYGTRNDIAIVWPPNRDPIIIAILSSR +DTEDATYDNDLIAKAAKVVLKEf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A097BQZ8_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVMIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillus sp. SDF0028 TaxID=2133754 RepID=A0A544VGT8_9BACL +-nQVHQQFVQLEKKYDARLGVYAIDTGTNQTI-TYRSNERFAYASTFKALAAGVLLQKNS +--IEQLDKVITYTKDDLVEYSPITEKHVDTGMTLEELAEAAIRFSDNTAVNLFLKELDGP +KGFEKALRQIGDQVTHADRYETELNEAVPGDIRDTSTPQALADDLKAFTLGNALPLDKRK +LLTDWMRGNATGDKLIRAGVPKDWEVADKSGAGGYGTRNDIAIVWPPNRAPIIIAVLSSR +DKKDAAYHNELIAEAAKVTMN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=UPI000554E4F0 +----AHKFMQLEKKFDARLGVYAIDTGTNRTV-AYRPDERFAYSSTFKALATGLVLQQNS +--LDELDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLEELGGP +DGFENGLRQIGDHVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPDSKRT +ILTDWMRGNTTGDELIRAAVPKGWEVGDKTGAGGYGTRNDIAIVWPPNRDPIIIAILSSR +DTEDATYDNDLIAKAAKVVLKEf +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A2K9YZQ7_RHILE +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPAKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1L3IN55_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNGAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A444HVY2_RHILE +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPAKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=A0A564NJ72_9ENTR +-nAIQQKLADLEKSTGGRLGVALIDTTDNSQI-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNKDVVNKMLEIKASDLVVWSPVTEKHLQSGMTLAELSAAALQYSDNTAMNKMIGYLGGP +EKVTAFARSIGDVTFRLDRTEPALNTAIPGDERDTTTPLAMAESLHKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PLQDAKSRKDVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. 88A TaxID=1131813 RepID=UPI000362BD2E +-rDLADRFARIEEASGGRLGIGLLDTGSGAHA-AHRGDERFPLCSTFKVLAAGAVLARVD +RGEDGLDRRLRYEPREIVPYSPVSGPRAGGEMTIAELCEAAVTLSDNTAANLLLGTMGGP +AGLTGHIRGFGDATTRLDRTEPDLNEAAPGDARDTTTPLAMAETLRRLVLADALSPASRA +LLTAWLVGCRTGDARLRAGLPQDWRIGDKTGSGENDTANDVAVIWPPRRAPLVLTVYLTG +ARTSPEARSATIASVARAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiaceae bacterium CPCC 101076 TaxID=2172049 RepID=UPI000E0DBE1A +----EAELADLERRSGGRLGVSVLDLGSIRRF-GYRPDERFAMCSTFKLLAAGYVLARVD +RGEERLDRRIVVRESDLVPYAPAVEKRLGGDMTMSELCDAAITLSDNAAANLILASYGGP +AGLTAYLRSIGDDVTRLDRNEPTLNEATPGDPRDTTSPAAILDTTRKLVLGDALSASSRE +QLKAWLIANTTGGARIRAGVPKDWIVGDKTGTGDKATSNDVAVLWPPGREPVLLTVYFTG +SALSRDTQSKVIADAASIVVR-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI00092F20DD +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDVRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=H6UQL7_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITXSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAXXRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase SHV-2 n=15 Tax=root TaxID=1 RepID=BLA2_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B7FDE0_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. TSH100 TaxID=652764 RepID=A0A4P7YKP3_9PROT +--AFAARMADLEGRTGGRLGVAMLDSGSGRLH-GWRGDERFPMCSTFKFLLAAAVLKTVD +QGKDLLDRQIPVTKADLVPYAPFSETRLNGTPTVAELCEAAMTLSDNVAANLLLPGVGNP +AGLTAFLRGIGDRTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMQRLLVGDVLRPDSRR +LLIDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAILWPEGRAPLLVASYLTQ +TAEGFRQQDAIHADVARAVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=UPI00028F5A93 +--QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAD +RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP +PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQPASRQ +RLADWLLASQTGDTRLRAGLPAGWRIGDKTGAGGHGTNNDIGVIWPRDGAPVLISAYLTQ +SSASREAQNAVLAEVGRIAAH-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A8I448_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDGRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000CA1B93D +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERFVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX90_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGSP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium TaxID=379 RepID=UPI000BE9765B +--NVERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD +KGDESLDRRVTYGKEKLVDYSPISEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +KLIAWLVASTTGKERLRAGLPADWKIGDKTGTGQNGSLGDIAVIWPPNRGPIVAAVYIAE +ATAPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Kaistia soli DSM 19436 TaxID=1122133 RepID=A0A1M5LJT5_9RHIZ +--DLDSKLAEIEASLAARVGVAILDTGSKRHW-LHRADERFPLCSTFKVLAAAAILRQVD +SGTDSLSRRVIIRQGDLVDYSPVTQRRTEGKMTLAEICAAALTTSDNTAGNMMLKAIGGP +AGLTSFARSIGDDTTRLDRWETALNEASPGDARDTTTPVAMARSLQAILLGPVLSARSKK +QLATWMVANRTGDAKLRAGLPARWLIGDKTGGGNHGTMNDIAIIVPPAREPVFVAVYITE +TAASFDARNAAIASIGRAIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Proteus TaxID=583 RepID=UPI000D696469 +-nTIEAQLSELEKYSQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE +KQAGLLDKNITIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP +TKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGLSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEKDAKNRKDIIAKAAEIVTKEf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia sp. E1130 TaxID=2041645 RepID=A0A5F1HSI2_9ESCH +-----VKVKDAEGKLGARVGYIELDLNSGKILeSYRSEERFPMMSTFKVLLCGAVLSRVD +AGQEQLSRRIRYSQNDLVEYSPVTEKHLSDGMTVKELCSAAITMSDNTAGNLLLKTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPDDERDTTMPAAIAATLRKLLTGTLLTPASRQ +QLINWMEADKVAGPLLRSALPTGWFIADKSGAGERGSRGIIAVLGPDRKPSRIVVIYTAG +SQATMDERNRQIAEIGASLIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0004ED735B +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRAAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00108406A3 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIARIGAALIEHw +>[subseq from] Beta-lactamase SHV-29 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=BLA29_KLEPN +-----EQIKQSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAAERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=D9IAH7_KLEPN +--AIQQKLADLEKHSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKADLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP +EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDERDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium phaseoli TaxID=396 RepID=A0A2U3D278_9RHIZ +--NIERRLAEVEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD +KGDESLDRRVTYGKEKLVDYSPISEEHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +KLIAWLVASTTGKERLRAGLPADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPMKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5L2T6_9BACT +--QVQEKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE +TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT +SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA +QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWTEDRAPLILVTYFTQ +PQQDAKGRKDILAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella africana TaxID=2489010 RepID=A0A455M837_9ENTR +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVLLCGAVLARVD +AGDEQLERRIHYRQQDLVAYSPVSEKHLADGMTVGELCTAAITMSDNSAANLLLGTVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVVPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Proteus columbae TaxID=1987580 RepID=UPI000C1E4497 +-nTIEEQLSTLEKYSQGRLGVALINTKDNSQI-TFRGEERFAMASTSKVMAVAAVLKESE +KQAGLLDKNITIKKSDLVAYSPITEKHLITGMSLAQLSAATLQYSDNTAMNKILDYLGGP +AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEQDAKYRKDIIAKAAEIVTKEf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. ST111 TaxID=1682204 RepID=A0A0N0ZGY4_9BURK +--AIRQRLAQIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKLLAAGFVLTRVD +SGQEDLERRVVFSKSDLVPYSPATSQHTRERMSVADLCKAAITLSDNTAANLLLASFGGP +AALTAFARSIGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELLLGERLSSSSRA +QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVTVYLTE +TSGDAARSNAAIANVGALIV--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A2Z4YKM9_RHILE +--NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] Class A beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A657NJH1_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Class A beta-lactamase RAHN-1 n=7 Tax=Rahnella TaxID=34037 RepID=E5DWJ0_9GAMM +--SVQQQLTALEKESGGRLGVMLIDTADNSQI-AYRADERFAMCSTSKFMAASAILKESE +VKKNLLTQHVALKQSDLVNYNPITEKHLNDGMTIGELAAAALQYSDNAAMNKLIEHLGGP +HKVTDYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPENKAPLVLVTYFTQ +PEKDAKSRRDVLASAAKIVTQGy +>[subseq from] class A beta-lactamase n=1 Tax=Phyllobacterium sp. SYP-B3895 TaxID=2663240 RepID=UPI001299DA1C +--DLDAAFKGLEEKTGARLGVAALDTASDSKI-EYRAHERFAMCSTFKFLAAAAVLAKVD +RKEEKLDRVIKYGKGDLVAGSPNTGKHVDEGMTLAALCEAAITLSDNTAGNLLLDNLGGP +KGLTQYARSLGDATFRLDRRETELNEATPGDPRDTITPAHILKDLQKTVLGNALAKSSRD +QLIEWLLANKTGDKRLRGGLPKGWSVGDKTGTSDSGMANDIAVIWPPSHKPILLAVYLYD +PKGTADSRNEIHRKVASLVAE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6Z9H7_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSPAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] class A beta-lactamase n=1 Tax=Herminiimonas arsenitoxidans TaxID=1809410 RepID=UPI000970442E +--AIQQELEKLEASAHGRFGVSAINTANGARV-QYRADERFPFCSTFKAIAAAAILKKSE +SNHQLLQQRVSYTKEEVEKYAPITAKHIADGMTITELCAATLQYSDNAAANFLMKELGGP +AAVTAYARTIGDDTFRLDRWEPELNTAIPGDLRDTSTPAAMQMSLQKLTLGNALALPQRE +QFVAWLQGNTTGGKRILAGVPKGWIVGDKTGTGSYGTTNDVGVIWPAKGAPIVAAIYFTQ +NEKDARPRDEVIASAARILVS-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00073ADB88 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTPPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=5 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A377X909_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGLNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5D3K437_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQKIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=A0A1V2BH63_RAOTE +heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPGERFPMMSTFKVPLCAAVLARVD +AGEEKLDRRIRYRQQDLVEYSPVTEKHLADGMTVAELCAAAITLSDNTAANLLLASVGGP +QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLTGSMLSAASRQ +QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMEDRNRQIAGIGETLVKHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0002CA5FFD +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMRDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=A0A0T9URP1_YERIN +--SLDKQLAELEQSANGRLGIAMINTANGSKI-LYRGAQRFPFCSTFKFMLVAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLIKQLGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALLPAQRS +QLATWLKGNTTGDATIRAGAPADWMVGDKTGSGDYGTTNDIAVLWPTKSAPIVLVVYFTQ +REKNAKSRHDVLASATKIILS-- +>[subseq from] class A beta-lactamase n=1 Tax=Rahnella bruchi TaxID=1510573 RepID=UPI000EA01EA5 +--SIQQQLTALEKESGGRLGVMLIDTADNSQI-AYRADERFAMCSTSKFMAASAILKESE +VKKDLLTQHVELKKSDLVNYNPITEKHLNDGMTMGELAAAALQYSDNAAMNKLIEHLGGP +QKVTDYARTLGDKTFRLDRTEPTLNTAIPGDDRDTSTPRAMALSLQHGTLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPENKAPLVLVTYFTQ +PQQDAKSRRDVLASAAKIVTQGy +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001033461F +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFLADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. CCGE1001 TaxID=640510 RepID=E8YVR7_9BURK +--AIRARLEDIQAQSGGRLGVSIVDTTSGLHA-GLHADERFPMCSTFKLLAAGAILARVD +RGEEDLQRRIVYSKSELVPYSPATSKHTRELMSVAQLCKAAITLSDNTAANLLLQTFGGP +AGLTAFVRSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELVLGERLSSASRA +QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGEHGTANDVAILWPPGRGPILVAVYLTE +TAGDAARGNAAIANVGALVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010312F7B +--NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLGRAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGKKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYITE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] Beta-lactamase n=3 Tax=Klebsiella TaxID=570 RepID=B5D619_KLEPN +-----EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] class A broad-spectrum beta-lactamase OKP-A-17 n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0003BE8F2F +-----EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001082EC33 +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000669A3B7 +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLAGGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPASMAERNQQIARIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKJ4_9BACT +hpETLAKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVAIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Proteus sp. TJ1640 TaxID=2050968 RepID=UPI000D694C3C +-nTIEAQLSELEKYNQGRLGVALINTEDNPQI-TYRGEERFAMASTSKVMAVAAVLKESE +KQAGLLDKNITIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP +SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEKDAKYRKDIIAKAAEIVTKEf +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A4Q8YCY4_RHILE +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI000648CB1C +--NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKDLNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00102F9E9C +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPVKELNPLFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Acidipila rosea TaxID=768535 RepID=A0A4R1KZA3_9BACT +-kSFRAQMEDLEKASGGRLGVAYLDTAHGTRA-GYREDERFPMCSTFKVLAAGKILLQVD +HGREHLDRMVHYTQKEIVSYSPFTATRVGNGASLREICVAALTLSDNTAANLMLASIGGP +AAVTAFARSLGDKVTRLDRTEPALNEALPGDPRDTTSPAAMVADLQTLLLGRTLSPGAKT +QLAEWMKQCKTGGERLRAGVPADWMVGDKTGSGDRGTANDIAILWPPHASPVMVAVYLTE +AKVGPAQRNETIAAVGRAIA--- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2D85B9 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLNRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. Leaf456 TaxID=1736382 RepID=A0A0Q6C6L3_9RHIZ +---FEDILARIEGRSGGRLGVAVLDTASGELT-GRRLDERFPLCSTFKTLAAAAVLARVD +GGQESLDRRIVFEREALVPYSPVTEARVGGSMSLAELCEAAVTRSDNAAANLLLRTLGGP +AGLTAHLHAFGDRTTRLDRTEPTLNEAAPGDPRDTTSPAAMVRLLAGLTLGSALSQPSRD +RLTGWLLANTTGGARLRAGLPPGWRIGEKTGTGENGTTNDAGVIWPPDGAAQVVAVYLTG +SDRPLADREAALANVAKAVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q9Z4Q6_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAMLARVD +AGDKQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Acidobacteriaceae bacterium TAA 166 TaxID=278963 RepID=UPI0005BC1573 +---LADTLRSLERRSQGRLGVAVQ-LPSGESA-QLRGDERFPMCSTFKFLAASLVLERVD +QGKEHLDRAISYSRSDLVSYSPETEKHAGGSMTVAELCKAALTLSDNTAANLLLSSFGGP +PAVTAFVRSIGDATTRLDRNEPTLNEATPGDPRDTTTPNVMLRNLRRILLEDVLKPSSRQ +QLTDWMLANTTGNAKYRAGLPSGWKVVDKTGSGSRGTNNDIGVLWPPAGKPILVTSYLTA +TPLSTDAANAIHAEVARAVAVSy +>[subseq from] Beta-lactamase n=1 Tax=Thalassospira permensis NBRC 106175 TaxID=1353532 RepID=A0A074JM51_9PROT +--RLLDAIHTVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAVLHKVD +RESETLDRRITYRSDDLVTYSPITEKHVDSGMTIGELCEAALHLSDNTAANLVLDVLGGP +DVLTAYLRDIGDDVTRLDRIEPDLNAATPGDARDTTTPNAMRATLTYLLLGDALSLESRQ +ILEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPERKPVIVAIYITH +TSASMEERNAAIADLGQEIA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL54_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAXIGASLI--- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. RO1 TaxID=2066034 RepID=A0A2N4SCQ0_9BURK +--QAEAQLAELERACGGRLGVAGFHTGSGARL-QHRAHERFPLCSTFKLMLAAAVLERST +TDASLLGRRVSVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP +TAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPAAMSDTVQRLALGDALGAPQRE +QMREWLLGNTTSTERFLAGVPAGWRVGDKTGAGSYGTTNDVGVLWPPSGAPLVLSVYLTF +PDKDAKGRNDVVASATRIAVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0009B3E6FE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=UPI000BB3752A +--DAETQLAELERTCGGRLGVSGFHTGSGARL-QHRAHERFPLCSTFKLVLAAAVLERST +TDASLLGRRVSVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP +AAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPAAMSDTVQRLALGDALGAPQRE +QMREWLLGNTTSTERFLAGVPKGWRVGDKTGAGSYGSTNDVGVLWPPSGAPLVLSVYLTF +PDKDAKNRNDVVAEATRIAVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000A36C115 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTJ0_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCVAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0002775483 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMVSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=2 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00037BDB45 +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E0F0DA +--SLDKQLAALEHSANGRLGIAMINTGNCTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDAKPRRDVLASATKIILS-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1) TaxID=269796 RepID=Q2RXW2_RHORT +-dALTARLIETEQRLGARLGATILDTHTGRNW-RYRAGERFPLCSTFKVIACGALLARVD +AGTEDLSQRVTFPESAVVAYSPVTKGRGEAGMTLAEICEAAITRSDNTAGNILLDRLGGP +AGVTTFARALGDTTTRLDRRETDLNEATPGDPRDTTTPEAMAKLMATLVLGKGLSVTSRD +RLTNWLLANKTGEAKLRAGLPKDWRIGDKTGGGDHGTMNDVAVVWPPGRQPLIIALYMTQ +TTASFEDRNRAIADIGRTLA--- +>[subseq from] Beta-lactamase n=3 Tax=Burkholderia glumae TaxID=337 RepID=C5AIM9_BURGB +--AARRQLAALDASFGGRIGVAALDSGSGARL-LHRADERFAFCSTFKTVLVAAVLTRAA +GDPRLLSSVIRYRRQDLVRYSPVSERHVETGMSVAGLCAAALQYSDNSAANLLIRMLGGP +AAVTAYARSIGDRWFRLDRLETDLNDAVPGDERDTTTPAAMLETLRRVTLGDALDAAGRA +RLVGWMLGNTTGDARIRAGVPAGWRVADKTGSGDYGSANDVAVIYPPRRAPIVLAVYTTR +DRKDAGYDNAAIASAARIVTAAf +>[subseq from] Beta-lactamase n=2 Tax=unclassified Methylobacterium TaxID=2615210 RepID=A0A0Q4U2E5_9RHIZ +-eNLADRFAQIEATSGGRLGIGLLDTGSGTQA-AHRGAERFPMCSTFKVLAAGAVLARID +QGEDSLDRRLRYAASEVVPYSPMSGPRADGEMTLAELCEAAVTLSDNTAANLLLGTMGGP +AGLTAQIRAFSDATTRLDRIEPDLNEAVPGDPRDTTTPLAMAQTLRRLVLADALSPSSRA +LLTAWLVGCRTGDARLRAGLPKEWRIGDKTGSGENDTANDIAVIWPPRRAPLVLTVYLTG +AKTSPEARSATIASVARAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A0B5NNS5_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTKWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKRATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella oxytoca TaxID=571 RepID=Q5DUJ7_KLEOX +--AIQQKLADLEKHSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKADLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP +EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0009B586AB +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKDLTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIAEAAEVVVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI000365D8C0 +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium phaseoli TaxID=396 RepID=UPI0007EA32CA +--NVERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD +KGDESLDRRVTYGKEKLVDYSPISEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +KLIAWLVASTTGKERLRAGLPADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola subsp. tropicalensis TaxID=2489014 RepID=A0A455LS80_KLEVA +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITMSDNSAGNLLLTTVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDMRDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTC6_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAVTLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. viciae (strain WSM1455) TaxID=755176 RepID=J0BUK4_RHIL1 +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCG +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPAKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar vazensis TaxID=180867 RepID=A0A243D5L1_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTKWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. DSM 27956 TaxID=1955699 RepID=A0A231RKC5_9BACI +----AHKFMQLEKKFDARLGVYAIDTGTNRTV-AYRPDERFAYSSTFKALAAGLVLQQNS +--LDELDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLEELGGP +DGFENGLRQIGDHVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPDSKRT +ILTDWMRGNTTGDELIRAAVPMGWEVGDKTGAGGYGTRNDIAIVWPPNRDPIIIAILSSR +DTEDAAYDNELIAKAAKVALKEf +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2C5252 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVVYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=V5N0A9_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWVVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Shewanella fodinae TaxID=552357 RepID=A0A4V2RSE7_9GAMM +hqAIQQQLSALEATTGGRLGIALIDTGTNARL-LYRGDERFPMCSTSKVMVVAAVLKQSE +QQQTLLTHKLAIKPTDLVNYNPVTEKHVNSEMTVAELSAAALQYSDNTAMNKLLSLLGGT +ARVTQFARDIGDQVFRLDRIEPELNTAIPGDERDSTSPLAMAQSLRQLTLGSALADPQRL +QLVEWLKGNTTGAASIRAGLPESWVVGDKTGSGEYGTTNDIAIIWPEAHAPLILVTYFTQ +QQQDAKARKDVLAAATQIVMRH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL50_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRXD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAXIGASLIKH- +>[subseq from] Beta-lactamase SHV-5 n=22 Tax=Bacteria TaxID=2 RepID=BLA5_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q4TVR4_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q5YCY3_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I2W6_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D9559DF +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRTDERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. V-88 TaxID=1938744 RepID=A0A1U6JS66_9BACI +----AHKFMQLEKKFDARLGVYAIDTGTNRTV-AYRPDERFAYSSTFKALAAGLVLQQNS +--LDELDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLEELGGP +DGFENGLRQIGDHVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPDSKRT +ILTDWMRGNTTGDELIRAAVPMGWEVGDKTGAGGYGTRNDIAIVWPPNRDPIIIAILSSR +DTEDAAYDNELIAKAAKVALKEf +>[subseq from] Beta-lactamase n=1 Tax=Morganella morganii TaxID=582 RepID=Q6EH43_MORMO +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAL-GPDGKPSRIVVIYTTG +SQATMDEANRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHY8_KLEPN +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKALLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIAKIGAALIEHw +>[subseq from] Beta-lactamase n=3 Tax=unclassified Photorhabdus TaxID=2620880 RepID=A0A329WKE7_9GAMM +--SLHKQLAELENSIKGRLGVALINTANGQEI-QYRGDERFPFCSTFKLILVAAVLHKSM +SQSELLAKHIHYRESDLLSYAPIARKNIHQGMSVTQLCAATVQYSDNTAANLLIKELGGL +EAVNRFVQGIGDPAFRLDRCEPDLNSAIPGDLRDTTTPAAMAASVKKIVLGEVLAAPQRE +QLIAWLKGNTTGDASIRAGVPAGWVVGDKTGMGDYGTTNDVAVLWSPKGVPVVLAVYFTQ +PQQDAESRRDVLASATRLVMAH- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=C3GJ41_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTKWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKRATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6Z9I0_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADECFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=G3KE68_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRXD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPXAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLI--- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phenoliruptrix BR3459a TaxID=1229205 RepID=K0DV60_9BURK +--AIRARLEDIQAQSGGRLGVSIVDTTSGLHA-GLHADERFPMCSTFKLLAAGAILARVD +RGEEDLQRRIVYSKSELVPYSPATSKHTRELMSIAQLCKAAITLSDNTAANLLLQTFGGP +AGLTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELVLGERLSSASRA +QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGEHGTANDVAILWPPGRGPILVAVYLTE +TAGDAARGNAAIANVGALVVE-- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=A0A0M3R8A6_KLEOX +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKADLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP +EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRT +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter pasteurianus TaxID=438 RepID=Q0VJ94_ACEPA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIE------- +>[subseq from] serine hydrolase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E1F21C5 +---LRARWAEIQRGTGGRLGISLLNSVTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKVRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP +PGLTRFLRGIGDTKTRS------------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E1F21C5 +------------------------------------------------------------ +------------------------------------------------AANLLFPLIGNP +PGLTRFLRGIGDTKTRSDRLEPAMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAGRDAALKAVAEAVR--- +>[subseq from] SHV family class A beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000AD04548 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVPRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Cobetia sp. ICG0124 TaxID=2053669 RepID=UPI000FDA4F69 +--------QEIEQRVGARLGVTVLDTANGRRV-SWRGDERFPMSSTFKVLACGNLLSRVD +ARQESLSRKVEIRPADLVTYSPVTERQVEGDMTLAALCRATITTSDNTAGNLILDAIGGP +VGLTNYLRTLKDDITRLDRRETALNEATPGDPRDTTTPDAMASTLQRLLLGEALSEASRL +TLQGWMLANTTGSDKLRAALPDDWQIADKTGGGGHGTNNDIAIIWPPNHAPLIVAVYLTE +SEAERAVRDAAIADVGRLLVS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZI70_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQPGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. 77 TaxID=1101192 RepID=UPI00037A6602 +---LADRFARIEQASGGRLGIGLLDTGGGAPV-AHRGGEPFPMCSTFKVLAAGAVLARVD +RGEDSLDRRLRYTLGEVVAYSPMSGPRAGGEMTLAELCEAAVTVSDNTAANLLLGTMGGP +AGLTAQLRDFGDATSRLDRTEPDLNEAVPGDPRDTTTPLAMAETLRRLVLGDALSPVSRA +LLTAWLVGCRTGDARLRAGLPKEWRIGDKTGSGEYDTANDVAVIWPPRRAPLVLTVYLTE +AKASPEARSAAIASVARAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0013C578F6 +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAASVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A649UI74_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEH- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus oleronius TaxID=38875 RepID=UPI000990C629 +--STNRKFAQLEKKFDARLGVYAIDTGTNKTI-TYRPDERFAYASTYKALAAGAVLQQYS +--MAQLDEVIHYSKDDLVSYSPITEQHIDTGMSLKEICEAAIRYSDNTAGNLLFHKLGGP +SGFEESLRQIGDHVTIANRFETELNEAIPGDLRDTSTPRALATSLKAFTLSDLLPAKKRV +ILANWMKGNTTGDKLIRAGAPKGWEVGDKSGAGSYGTRNDIAIVWPPNREPIIIAILSSR +DTKDATYNDELIARAAKLVFK-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A7LIT2_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAAERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Oxalobacteraceae bacterium AB_14 TaxID=1158293 RepID=UPI000368B126 +----ASLLAKLEGESGGRLGVAALNTADGRQL-LHRADERFPFCSTFKMMLSAAVLAREP +---ALLRKRVRYTRKDLVTYSPVTEKHVGTGMTVAALCEATLQTSDNTAANLLMQLIGGP +AAVTAFARSIGDMEFRLDRIETALNSALPGDPRDTTTPASMAESLHKLLLGDGLGVAQRK +QLKDWMLGNTTGDTRIRAGVPSASLVADKTGTGDYGSTNDIGVIWQPGKAPIILVIYLTQ +PGKDDKARSEILAEATRIVVEAf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. Bc-h TaxID=1943632 RepID=A0A1V9UNN3_9PSED +--SIERQLAALERRHGGRLGVAILDTGTQRLI-SHRGDERFAMCSTFKALTAAHVLARVD +RKEEDLSRVIVYGQDQLVTYSPVTEKHTGEGLSVGSICEAAVTLSDNTAANLLLDSFGGP +KGLTAWLRTIGDQTTRLDRREPELNENRPGDLQDTTTPIAMLHSLRTLVIGDVLSGASKV +QLIAWLVSNKTGDQKLRAGLPKGWRVGDKTGSGSNNASNDVAIIWPTGRPPLIVTVYYSE +SKASSEQINSLMAEVGRLVAK-- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=Q2YHZ4_KLEPN +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] class A extended-spectrum beta-lactamase OXY-1-6 n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI000016F82E +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVPVTYFTQ +PQQDAKSRKKVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=B8YHZ8_KLEPN +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Bacillus obstructivus TaxID=1914540 RepID=A0A1L8ZP65_9BACI +--STNRKFAQLEKKFDARLGVYAIDTGTNKTI-TYRPDERFAYASTYKALAAGAVLQQYS +--MAQLDEVIHYSKDNLVSYSPITEQHIDTGMSLKEICEAAIRYSDNTAGNLLFHKLGGP +SGFEESLRQIGDHVTIANRFETELNEAIPGDLRDTSTPRALATSLKAFTLSDLLPAKKRV +ILTDWMKGNTTGDKLIRAGAPKGWEVGDKSGAGSYGTRNDIAIVWPPNREPIIIAILSSR +DTKDATYNDELIARAAKLVFK-- +>[subseq from] Beta-lactamase n=2 Tax=Bordetella bronchiseptica TaxID=518 RepID=A0A5A4M9B6_BORBO +--QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAD +RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP +PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALHPASRQ +RLADWLLASQTGDTRLRAGLPAGWRIGDKTGAGGHGTNNDIGVIWPRDGAPVLISAYLTQ +SSASREAQNAVLAEVGRIAAH-- +>[subseq from] Beta-lactamase SHV-46 n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=BLA46_KLEOX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLNSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00103A6392 +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVLAKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I6N3_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQPERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTTFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00035CC86D +--NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLGRAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Staphylococcus capitis TaxID=29388 RepID=UPI000D19893C +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIEGP +KQLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTC4_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGLGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0014420E9C +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSESFPMCSTFKALAAAFVLARAD +KGEENLDRRVNYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=UPI0005E764A0 +--SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLAAAVLGRSQ +SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL +AMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRE +QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPVKGAPLVLVVYFTQ +LKKEAEPRRDVLAAATKIVLAH- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00144101D8 +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSESFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPLSEKHAGTDMTLAELCEAAVKVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGRERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATASAKELNPVFAEVGRMIVE-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D19F156 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGVRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pasteurii TaxID=2587529 RepID=A0A5P1KAT9_9ENTR +-dTLQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP +EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=Q8GM80_KLEOX +-dTLQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP +EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacter vibrioides TaxID=155892 RepID=A0A290MLG6_CAUVI +--DLTSRINALEKASGGRLGVAVLDTHTGRRF-AWRGDQRFRMCSTFKTPLAAAILRRVD +QGRERLDRRIRYGRDVLIAHSPAVDKHLGQGMTVGALCEATITLSDNAAANLLLDALGGP +SALTRFLRAIGDETTRCDRREPELNGGAPDDPRDTTTPVAIVETWRTLLLDDVLTPASRH +QLAEWVVANRTGDRRLRAGLPRGWRVGDKTGSDGRAITNDVAIAWPPGRKPLLLAVFHDQ +GAPDDAARNAVLADTARAVVA-- +>[subseq from] Beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0002184FA8 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDHWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI0006C39AD4 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR +DEKGAAYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6Z9I8_ECOLX +--DVQQKLAELERLSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTATPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE4B8D4 +--NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKDLNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=E7CER3_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMLSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax cavernicola TaxID=1675792 RepID=A0A3A1WEF3_9BURK +--DAEAQLAELERACGGRLGVTGFHTESGARL-QHRAHERFPLCSTFKLVLAAAVLERSA +TDASLLGRRVSVGKGDLVSHSPVAEKHLATGMTVREMCAATMQYSDNAAANLLLKVLGGP +AAVTAFARRIGDSTFRLDRMEPELNTSIPGDPRDTTTPAAMADSVQRLALGDALGAPQRD +QMREWLLGNTTSTERFLAGVPAGWRVGDKTGAGSYGSTNDVGVLWPPSGAPLVLAVYLTF +PDKDAKNRNDVVASATRIAVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar mexicanensis TaxID=180868 RepID=A0A242WEJ4_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIAEAAEVVVNAf +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010827373 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMLSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. 6HR-1 TaxID=1141884 RepID=A0A4Z0NKY3_9RHIZ +--DAAARLAQLERRDGGMLGVEVRDTATGRRF-GHRADERFPLCSTFKAVAAAAVLARAD +TGQDDLNRRITYTRDDILSYAPVTAKHVETGMTLAELCAAAVVWSDNTAANLMLATLGGP +EGITAFARAHGDTVTRLDRTEPTLNTAIRGDLRDTTTPAAMVGLLDTLLLGQALSAASRA +RLTGWMQESPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG +SPAEPAARDALHAEVGRLIARSf +>[subseq from] Beta-lactamase n=2 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A444IN82_RHILE +--NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus halotolerans TaxID=260554 RepID=UPI000BFF07C6 +--ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS +--IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP +KGFEEALRQIGDKVTVADRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK +ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR +DKKDATYDNELIAQAAKVTIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000A111E8C +--ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS +--IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP +KGFEEALRQIGDKVTVADRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK +ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR +DKKDATYDNELIAQAAKVTIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00122D23A5 +-----------EDQLGARVGYIELDLNSGKILeSFRLEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI0005E414C6 +---LGNQLAELERNSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ +TQPGLLDKHIKYHESDLLSYAPITRKNLAHGMTVSQLCAATMQYSDNTAANLLIKELGGV +ASVNAFARSIGDQVFRLDRLEPDLNTALPNDPRDTTTPAAMADSMNKLVLGDALPAAQRE +QLALWLKGNTTGANTIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPTQGAPIVLVIYFTQ +REKDAKPRRDVLAAATKIVLSH- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus halotolerans TaxID=260554 RepID=UPI0009F1B4AA +--ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS +--IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP +KGFEEALRQIGDKVTVADRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK +ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR +DKKDATYDNELIAQAAKVTIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI00040AEAFF +-dDVTERLRQLEERTGGRLGVAVLDTETNISF-VHRETERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +QGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRK +QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE +AKAPLDDLNPVFADIGRIVAD-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2R2IPE8_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=UPI00131F6698 +-----HKFMQLEKKFDARLGVYAIDTGTNQTL-AYRPDERFAYSSTFKALAAGLVLKQNS +--MDELDEVITYTRDDLVTYSPITEQYVDTGMTLREISDAAIRYSDNTAGNLLLQELGGP +DGFENALRQLGDHVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLLEDKRA +LLTDWMRGNTTGDELIRAGVPKGWEVGDKTGAGGYGTRNDIAIVWPPNRAPIIIAILSSR +DTEDAAYDNELIAKAAKVVLKEf +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillus sp. A3 TaxID=1337054 RepID=A0A0P9DTZ5_9BACL +-----DEFIQLENKFGARLGVYAIDTGTSRTI-AYRPEERFAFASTYKALAAGAVLQQSS +--IANLDKVITYTKEDLVTYSPITEKHVETGMTLRDICDAAIRYSDNTAGNLLLKELGGP +KGFETVLKKIGDNVTTSARFETELNQAIPGDTRDTSTPIALATTLQAFTVGDVLSTDKRK +LLTDWLRGNTTGAKLIRAGAPEGWQVGDKTGAASYGTRNDIAIVWPPNRDPIIIAILSSR +DKQDSAYNDDLIAQAAKIAMDAf +>[subseq from] Beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=A0A209AJR3_YERFR +----GNQLAELERKSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ +TQPDLLNKHIKYRESDLLSYAPITRKNLAHGMTVSQLCAATMQYSDNTAANLLIKELGGV +ESVNAFARSIGDQAFRLDRLEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALPAAQRE +QLTLWLKGNTTGAETIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPTQGAPIVMVVYFTQ +REKDAKPRRDVLAAATKIVL--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A292G2V0_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAES---------------- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas mosselii TaxID=78327 RepID=UPI0007853550 +hdPLRQAMQQLEAASGSTIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHRNE +AEPGLLARRIAYGAEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP +PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLTDGLPAGAQQ +QLQAWLKGNTTGDARIRAGLPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG +TKQDAPWNSETIAAATRIVVEAw +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Leaf177 TaxID=1736287 RepID=A0A0Q5PHC1_9BURK +---VGEELARIEARSGGRLGVSILDTGSGKRA-GLRADEAFPMCSTFKFLAASFVLARVD +QGQEDLKRKIVYSKSDLVEYSPVTQHHTGPALSVGDLCAAAITLSDNTAGNLLLASFGGP +PALTAFLRTLGDQFTRLDRNEPTLNESTPGDPRDTTTPNAMLANMRTLLLTDRLSVSSCA +QLRDWLIANQTGGKRIRAKLPKDWRVGDKTGTGSHGSTNDIAIIWPPGRPPLLVSAYLTQ +TNAETARREAAIADVGKLLV--- +>[subseq from] Class A beta-lactamase n=8 Tax=Rhizobiales TaxID=356 RepID=A0A222H047_RHIML +-dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD +RGKEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +QGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGLVLSQEGRK +RLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE +AKAPLDDLNPVFADIGRIVAD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKB6_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=D4QFM2_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDGVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDC6324 +-dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD +RGKEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +QGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGLVLSQEGRK +RLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE +AKAPLDDLNPVFADIGRIVAD-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DD34A4F +-----EQIKQSESQLSGRVGMIEMDLASGRXLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVXRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=3 Tax=Rhizobium leguminosarum TaxID=384 RepID=C6ASM4_RHILS +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTNWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLNTLGNLTLGSVLAEASCD +RLIAWLVTSTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q5VCA8_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMISTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=A0A0G4QB59_PROVU +-nTIEAQLSELEKYNQGRLGVALINTEDNSEI-TYRGEERFAMASTSKVMAVAAVLKESE +KQAGLLDKNIAIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP +SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEKDAKYRKDIIAKAAEIVTKEf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B8Y883_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIELw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5Q3M162_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Massilia umbonata TaxID=864828 RepID=A0A4P8HM84_9BURK +---ATGSFAAIERDLKGRLGVAVIDTATGTAS-GHRLDERFPMCSTFKALLAAQALARDA +REPGFAERRLRYAKADLVGHSPVTGKHVDTGMTVAELCAATVQYSDNAAANTLMKELGGP +AGLTAFMRGIGDTTFRLDRWELELNTAIPGDERDTTTPLAMARTLQKLVLGDALPAPQRQ +RLKQWLVGNTTGDRRIRAAVPANWQVGDKTGTGAYGVTNDIGIVFPPGRAPLVVVVFTHQ +PDKDADSREDVVVAGAR------ +>[subseq from] Beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0002A54C26 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADRTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2U9GMT4_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVE +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia rhynchosiae TaxID=487049 RepID=A0A2N7WND9_9BURK +--AIRARLKQIEAESGGRLGVSIIDTASGLHA-GLHADERFPMCSTFKLLTAGAILSRAD +RGEEDLQRRIVYSQSELVSYSPATSKHTRERMTVAELCKAAITLSDNTAANLLLASFGGP +AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELVLGERLSSSSRA +KLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPVLVAVYLTE +TAGNAARCNAAIADVGALVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q7WYH2_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQL +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTC5_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGWALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Enterobacter asburiae TaxID=61645 RepID=UPI0007F8AE3B +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRVARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=A0A2J0YUH7_RHIML +-eDVTERLRRLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD +RGEEKLERRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +EGLTSWLRSIGDETTRLDRTEPELNEARKGDPRDTTTPAAMLDTLGKLVLGPVLSQEGRQ +QLIDWLVANKTGDARLRAGLPKDWRIGDKTGTSMTGAVSDIAVAWPQGRGPILICVYMGE +AKAPLDDLNPVFADIGSIVAD-- +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI0007D0C6F0 +--AIHQKLTALEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEP--NTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGTGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM3983 TaxID=1038867 RepID=UPI0003FE0F03 +-----KAIEQLELKSGGRLGVSVLDATTGIPI-HHKGDERFPMCSTFKVLASAAILKNAG +SKLELLERRVRFEQADIVENSPVTREHVGGEMSLRELCDAAITMSDNTAGNALLNNIGGP +AGLTSFARSLGDKMTRLDRTETELNEATPGDPRDTTTPNAMAANLKRLLLGDALLPEGRD +QLAKWLIANKTGNSRLRAGLPQGWRVGDKTGAGEHGTTNDVAIVWPPERSPLIVAVYLTG +ASLDPNGRNDVIASVGREVGKAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1W5VPT5_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASL---- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1Z1VQL0_KLEPN +----LEQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus anthracis TaxID=1392 RepID=A0A1T3V451_BACAN +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=D5LGB4_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAELDQQIAGIGAALIEHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Bacillus vallismortis TaxID=72361 RepID=UPI000287A7D0 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASLQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0011C8A891 +-----EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQHIARIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus (strain 03BB102) TaxID=572264 RepID=A0A125U4Q9_BACC3 +-qATHKEFSQLEKKFDARLGVYAINTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q5VXW0_9BURK +------------AEAGGRLGVMALDTGTGSRW-AWRADERFPACSTFKVLAAAAVLARSV +DDAGLLTRRVRYPASELVTYSPVTEKHLADGMTIAELCAAALQYSDNTAGNLLLRQIGGP +AGVTNYARSIGDSTFRLDRWETELNTAIPGDPRDTCTPAGMAHNLQRLLLGDALAPAPRA +QLQAWMRGNTTGATRIRAGVPAAWAVADKTGSGDYGSVGDIGVTWRPDAAPIVLALYFAQ +ATKDASMRSDVLAAAARIVAD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2S9HMF8_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTKQTV-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5P8NAY5_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWHADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAKRNQQIAGIGAALIEHw +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI001402FDFB +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITMSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZI82_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNRTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0003672711 +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +RLIAWLVTSTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf85 TaxID=1736241 RepID=A0A0Q4UAD0_9RHIZ +-rDLADRFARIEEASGGRLGIGLLDTGSGAHA-AHRGDERFPLCSTFKVLAAGAALARVD +RGEDGLDRRLRYELREVVPYSPVSGPRAGGEMTIAELCEAAVTLSDNTAANLLLGTMGGP +AGLTGHIRRFGDATTRLDRTEPDLNEAAPGDPRDTTTPRAMAETLRHLVLADALSPASRA +LLTAWLVGCRTGDARLRAGLPKDWRIGDKTGSGENDTANDVAVIWPPRRPPLVLTVYLTG +ARTSSEARSATIASVARAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=R4RRV8_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRCVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus anthracis TaxID=1392 RepID=A0A640LDP3_BACAN +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia sp. IP36721 TaxID=2161716 RepID=UPI000EB3F433 +---LSEQLTALEEKAQGRLGVSLINIQSGKEL-QYRGNEAFPFCSTFKLVLAAAILRQSM +SQPVLLEKHITYSEADLLSYAPIARENLGKGMTIAALCAAALQYSDNTAANLLIQQLGGL +EGVNKFTQSLGDTAFRLDRWEPELNSAIPGDPRDTTTPSSMAALVKKIQFGDGLAPAQQQ +QLAQWLKGNTTGNASIRAGVPADWLVGDKTGSGDYGTTNDVAVLWPPTGAPLILAVYFTQ +HKKDAESRRDVLAEATRIILAQy +>[subseq from] Beta-lactamase n=1 Tax=Bacillus anthracis TaxID=1392 RepID=A0A2A7DAM0_BACAN +-qATYKEFSQLEKKYDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDNRDTSTAKAIATNLKEFTVGNALPDHKRN +ILTDWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKDAPYDNQLIAEAAEVIVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus sp. A9 TaxID=1284352 RepID=UPI0003721328 +--SLASSFRALEQQHQARLGVYAIDTGTGKVV-AYRHNERFAFASTYKALAAAAVLQQNS +--IADLDRVITYSAKDLVEYSPVTEKHVDTGMTLREICEAAIQYSDNTAGNILFQELNGP +AGFQQALRQLEDRTTRSERIEPELNAAVPGDPRDTSTPRALARDLRLFTTGKVLSQDKRQ +LLAEWMKGNTTGDDLIRAAAPKGWIVGDKTGSASYGTRNDIAVVWPPGRSPIIITVLTGH +TDKNAKVDNELVAKAAKMVFD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus anthracis TaxID=1392 RepID=A0A1J9W355_BACAN +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAITTNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I6N7_KLEPN +-----EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9F918_KLEPN +-----EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX87_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASSRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Yersinia entomophaga TaxID=935293 RepID=A0A3S6EXT5_YERET +---LSEQLTALEEKAQGRLGVSLINIQSGKEL-QYRGNEAFPFCSTFKLVLAAAILRQSM +SQPALLEKHITYSEADLLSYAPIARENLGKGMTIAALCAAALQYSDNTAANLLIQQLGGL +EGVNKFTQSLGDTAFRLDRWEPELNSAIPGDPRDTTTPSSMAALVKKIQFGDGLAPAQQQ +QLAQWLKGNTTGNASIRAGVPADWLVGDKTGSGDYGTTNDVAVLWPPTGAPLILAVYFTQ +HKKDAESRRDVLAEATRIILAQy +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum rhizosphaerae TaxID=346179 RepID=UPI00067D026F +---VVSRLAKLEASVGGRLGVDIIDSATQRRW-GYRAGERFPMCSTFKFLASAAVLKRVD +AGQEQLERRIIYGNDVLVSYSPTTSKHVGGNLTLGQLCEAALTLSDNTAANLILKSLGGL +EPFNKFIKSLGDRQTRLDRFETELNTAIPGDLRDTTTPAAMSDNLQRILLGDVLSPSSRE +QLIAWMRSNKTGDRRVRAGMQPGWSVGDKTGSGDYGTTNTIAIIWPPQGKPLLASVYLTR +TKAPEEQRNSVLAEVGKLIV--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. R634 TaxID=1764274 RepID=A0A246SJ26_9RHIZ +--NVERRLAALEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGDESLDRRVSYGKEKLVDYSPISEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +PGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTETSCS +RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYITE +ATVPAKDLNPIFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A9CSQ3_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALSGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1B2BII5_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALSGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Photorhabdus namnaonensis TaxID=1851568 RepID=A0A1B8YD02_9GAMM +--SLHKQLTELENSTKGRLGVALINTENGQEI-QYRGDERFPFCSTFKLILAAAVLHKSM +SQPELLAKHIHYRESDLLSYAPIAHKNLNQGMSVAQLCAATVQYSDNTAANLLIKELGGL +EAVNRFTQGIGDPAFRLDRREPDLNSAIPGDLRDTTTPAAMAASVKKIVLGEVFGASQRE +QLIVWLKGNTTGDASIRAGAPAGWVVGDKTGAGDYGTTNDVAVLWPLKGAPVVLAVYFTQ +PQQDAESRRDVLAAATRLVMAH- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDA97F5 +-dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +DGLTSWLRSIGDETTRLARTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRQ +QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE +AKAPLDDLNPVFADIGRIVAD-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007E90138 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAVAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=B7FDD9_KLEPN +---------ESESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=A0A5P2MT43_BORBO +--QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAD +RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP +PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQPASRQ +QLADWLLASQTGDTRLRAGLPAGWRIGDKTGVGGHGTNNDIGVIWPRDGAPVLISAYLTQ +SSASREAQNAVLAEVGRIAAH-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS015802 TaxID=2033486 RepID=A0A2A8VDE6_9BACI +----NQKFMQLEKKFDARLGVYAIDTGTNRTV-VYRPDERFAYTSTYKALAAGAVLQQHS +--MDELDEVITYTKDDLVTYSPITEQYVDTGMTLREICDAVIRYSDNTAGNLLFQELGGP +DGFENALRQIGDHVTEADRFETELNSAIPGDIRDTSTARALATNLKAFTVDDVLPVDKRT +ILTDWMRKNTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPNRDPIIIAILSSR +DTKDAAYDNELIAKAAKVVLNSf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium etli TaxID=29449 RepID=UPI00057FBAC9 +--NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP +AALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLINWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGHIAVIWPPDRGPIVAAVYIAE +ATAPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=A0A483KAC9_9ENTR +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLHQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNSKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium symbiodeficiens TaxID=1404367 RepID=UPI00112A2B1F +-----EAIKQLELKSGGRLGVSVLDTMTGVPI-HHKGDERFPMCSTFKVLAAAAILKAAG +SKLEALERRVRIEQGDLVEYSPVTREHIGGEMTLRELCDAAITRSDNTAGNALLKNIGGP +AGLTSFARSLGDDITRLDRTETGLNEAKPGDPRDTTTPNAMAANYRRLLLGDVLLPEGRD +QLGQWLIANKTGDTRLRAGLPQGWRVGDKTGAGENGTANDVAIVWPPKRSPLIIAVYLTG +ASLDPNGRNDVIASVGREVGKAf +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=UPI000290600C +--QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAE +RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP +PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQPASRQ +RLADWLLASQTGDTRLRAGLPAGWRIGDKTGAGGHGTNNDIGVIWPRDGAPVLISAYLTQ +SSASREAQNAVLAEVGRIAAH-- +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=UPI000461EDFB +--QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAE +RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP +PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQPASRQ +RLADWLLASQTGDTRLRAGLPAGWRIGDKTGAGGHGTNNDIGVIWPRDGAPVLISAYLTQ +SSASREAQNAVLAEVGRIAAH-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=E5KCK0_ACIBA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEI-------- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=UPI0011A43884 +--SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLAAAVLGRSQ +SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL +AMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDTLAAPQRE +QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVIYFTQ +LKKEAEPRRDVLAAATKIVLAH- +>[subseq from] class A beta-lactamase n=1 Tax=Candidatus Fukatsuia symbiotica TaxID=1878942 RepID=UPI00093528D5 +--SIQEKLSELEKISGGRLGLFAINTANNLTV-QYRAVERFPVTSTFKVLAVAAILKQSV +TDRQLLQQRITYNPKDLVSYSPITEKHLG--MTVEELCAATIQYSDNTAVNLLMKLLGGP +KAVTEFARSIGDHTFRLDRWETDLNSAIPGDLRDTSTPVAMAKSVQRLVLGDALPPAQRE +KLQVWLKGNTTGDASIRAGIPEGWVVGDKTGGGDYGTTNDIGVLWPPTAAPIVVAIYFTQ +NEKDAQTRKDVIASATRILISAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YE63_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVTAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTASPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009E2C92E +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=2 Tax=Marinobacter lipolyticus TaxID=209639 RepID=R8AY12_9ALTE +hnSLIKTVESIASEIEARVGFAAYDLESGQRW-EYQADQRFAMSSTFKTLACAALLHRVD +AGQENLERTVSFSESDLVTYSPITEKYAGGQMTLSDLCEAALTRSDNTAANLILRSLGGP +EKVTSFARRLGDDVTRLDRWETELNEAAPGDNRDTTTPNAMVKNLQSLLLGDALSGKSRE +QLHDWLKRNQVADGLFRAVVPEGWIVADRTGAGGFGSRSITAIIWPPERQPIVVALYLTQ +TEASFSERNEAIAEIGEAIV--- +>[subseq from] Beta-lactamase n=3 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8GF08_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=K7U492_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A384X512_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWHADERFPMMSTFKVVLCGAVLARMD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A329F905_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGALLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0011197AF1 +-----EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=F6K6C7_PROMI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKH- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q6ZY74_KLEPN +-----EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium symbiodeficiens TaxID=1404367 RepID=A0A2U8QB09_9BRAD +-----EAIKQLELKSGGRLGVSVLDTMTGVPI-HHKGDERFPMCSTFKVLAAAAILKAAG +SKLEALERRVRIEQADLVEYSPVTREHIGGEMTLRELCDAAITRSDNTAGNALLKNIGGP +AGLTGFARSLGDDITRLDRTETGLNEAKPGDPRDTTTPNAMAANYRRLLLGDVLLPEGRD +QLGQWLIANKTGDTRLRAGLPQGWRVGDKTGAGENGTANDVAIVWPPKRSPLIIAIYLTG +ASLDPNGRNDVIASVGREVGKAf +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium loessense TaxID=158890 RepID=A0A1G4PDG6_9RHIZ +-dDIEHRLAELEKRTGGRLGISVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD +KGEENLERRVIYNQEKLVSYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLLLESVGGP +KALTKWLRSIGDRATRLDRWETALNEGKKGDPRDTTTPDAMLDTLGNLALGSVLSEPSRE +KLIEWMLANTTGDARLRAGLPRAWKVGDKTGTGDNGSAADIAIIWPKGRGPILVTTYIAE +ATAPVKELNPVFVEVAKIVA--- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=M9T8M5_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAASQRQ +QLVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q1WBU3_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALI--- +>[subseq from] Class A beta-lactamase n=1 Tax=Bradyrhizobium sp. LMTR 3 TaxID=189873 RepID=A0A1B9YX55_9BRAD +-qRLIDEIRRLERGSGGRLGVCVLDTATDTRH-AHRGDERFPMCSTFKMLAASAILARVD +AGKEQLTRRVTFDASALIVYSPVTEKRVGGDMTLAEICEAAVTLSDNTAGNLLLAGIGGP +PGLTAFVRSLGDQVTRLDRDEPSLNEALPDDIRDTTTPNAMASNLQALILGKALSAASRE +QLTAWLVANKTGDARLRAGFAKDWRVGDKTGTGARGTNNDVAVIWPPGKAPIVITAYLTG +ATVSAAQQNATLASVARAVS--- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B0DC1CF +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPSDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLI--- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=R4RZD7_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQHLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Class A beta-lactamase n=1 Tax=Mesorhizobium plurifarium TaxID=69974 RepID=A0A2T3ETP8_MESPL +--DVMERLRRLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD +RGEEELDRRITFGEEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +QGLTSWLRSIGDETTRLDRTEPDLNEATKGDPRDTTTPAAMLDTLGKLVLGSVLSEEGRK +QLIDWLVANKTGDSRLRAGLPKDWRIGDKTGTSMTGAASDIAAAWPRGRGPILICVYTGE +AKAPLDDVNPVFADIGRIVA--- +>[subseq from] Beta-lactamase n=1 Tax=[Empedobacter] haloabium TaxID=592317 RepID=A0A5C7CEW2_9FLAO +-----SAFAALERKFKGRVGVAAIDTASGKVI-GNRQDERFPFCSTFKTIVAAAVLARSA +TEPGFLGKRLRYTQADIKPHSPVSEKHVEAGMTAAELCAATIQYSDNAAANILMRELGGP +AAITAYARTLGDTTFRLDRWETELNSAIPGDERDTTTPLAMARTLQKLLVGDGLPPAQRQ +QLKDWMVGNTTGATRIRAGVPKGAVVADKTGTSGYGVANDMGVIYLPQRAPIVLVVFTHG +ATEQAEARSESVAEATSVALR-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000B414920 +-----EQITLSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIAKIGAALIEHw +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI0007CD0252 +-----EQITLSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIAKIGAALIEHw +>[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F54395A +-----------ESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. TaxID=1872122 RepID=A0A519IFX5_9BURK +-----EALARIEASVGGRVGVAVLDTHTGRQI-AHRGGERFPMASTFKLLLAAQTLRRVD +QGQDKLDRRITYAKKDLVTYSPVTEPHADGALTVEELCAGTMTLSDNTAANLLLASNGGP +AALTAYVRSLGDSITRLDRNEPALNEAKPGDPRDTTTPQAMVHCIQALALGDALSPASRE +KLQGWLLANKTGDRRLRARLPEGWKAGEKTGTASRGTSNDAGVFWPHGRKPVVVSCYLTG +GEAPPEQREAAMAEIGALVAQ-- +>[subseq from] Class A beta-lactamase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3MVZ3_9BURK +----SARLAALESESGGRLGVSVREPGRAAPW-GHRQDERFPMCSTFKLIAASGVLALSA +SDTGLLDRRIAYTKAELVSYSPVTQQHAGDGMTVAQLCAAALQYSDNTAGNLLIRLLGGT +EAVTAYARSIGDNAFRLDRWETELNTAIPGDWRDTTTPAAMAMSLERVALGDALGAPQRA +QLVAWLRGNTTGAARIRAGVPADWQVGDKTGGGDWGTTNDVAVLWPPGRPPLVVAMYFTQ +PQQDAAARSDVLAAAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. DrBHI1 TaxID=2006091 RepID=A0A246GWL9_9PSED +hdPLRQAMQQLEAASGSTIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHRNE +AEPGLLARRIAYGAEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP +PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLTDGLPAGAQQ +QLQAWLKGNTTGDARIRAGLPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG +TKQDAPWNSETIAAATRVVVEAw +>[subseq from] class A beta-lactamase n=1 Tax=Chromobacterium subtsugae TaxID=251747 RepID=UPI0006411387 +--SAAARLAALEADFGGRLGVCALDTASGAEL-GHRVGERFPFCSTFKAMLVGAVLARSA +KQPGLLAERIHYARRDLVEYSPRTEPHLADGMTVAELCAAAVQYSDNSAANFLLKLLGGP +AALTAYMRSIGDESFLLERWEPELNRAVPGEARDTSTPQAMAQSLRRLALGDALAPHAQR +QLVEWLRGNTTGAEKIRAGVPAGWVVGDKTGNGRYGSSNDIAVLWPPGRAPAVLTVFTTQ +ALEDAKQRHQVVAAAARIAAD-- +>[subseq from] Beta-lactamase n=1 Tax=Polaromonas sp. Pch-P TaxID=2082385 RepID=A0A5Q3HAM9_9BURK +--AVTARLQAIERESGGRLGVSILETGNGARW-GYRAGERFPMCSTFKLLAAALILHRVD +KGQEQLDRKIIVKPSDIITHSPTTKQYVGTQITIAQLCEATVTLSDNAAGNLLLESFGGP +AGLTAYTRSLGDTMTRLDRNEPSLNEATAGDKRDTTTPDAMVSTIQKIVLGTALSEASRK +QMTQWLLDNKTGDTRLRALLRPGWRVGDKTGTGGHGSTNDVGILWPPGRAPVVVAAYLTG +TSRPIAQREATLAKVGELAA--- +>[subseq from] Beta-lactamase n=1 Tax=Thalassospira xiamenensis TaxID=220697 RepID=A0A367W4M1_9PROT +--RLLDAVQTVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAVLHKVD +RESETLDRRITYRSDDLVTYSPITEKHVDSGMTIGELCEAALHLSDNTAANLVLDVLGGP +DVLTAYLRDIGDDVTRLDRIEPDLNAATPGDARDTTTPNAMRATLTYLLLGDALSLESRQ +ILEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPERKPVIAAIYITQ +TSASMEERNAAIADLGQEIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Proteus genomosp. 5 TaxID=1311788 RepID=UPI000D68C69C +-nTVEEQLNTLEKYSQGRLGVALINTEDNSQI-IYRGEERFAMASTSKVMAVAAVLKVSE +KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLGGP +AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVIYFTQ +QEQDAKYRKDIIAKAAEIVTK-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=V5N0U5_PROMI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMTDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDELNRQIAEIGASLIKHw +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000C7B649C +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRISYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00050C8427 +-----EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Reyranella sp. TaxID=1929291 RepID=A0A521QRY0_9PROT +-----SALRELERRNGGRLGVALLDTASGRRV-AHRGDERFPMCSTFKFLAAALMLARVD +RGEERLDRRVVFAESDLVPYSPATKEHAGPGMTVDAICAAAMTLSDNTAGNLMLASFGGS +AGLTAFVRGLGDPMTRLDRIETELNEGAPGDPRDTTSPLAMLGTMQKLVAGNVLSAGSRE +RLIGWLVANKTGDKRLRAGLPASWRVGDKTGTGGNGSANDIAVAWPPGRAPVFIAAYYTG +STISDEARSAAIAEAGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A4Q8YW28_RHILE +--NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLGRAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGKKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Metallibacterium scheffleri TaxID=993689 RepID=A0A4S3KLR3_9GAMM +--RLQRQFARIEAASGGRLGVAMLDLRTGLHA-SHRGGERFPMCSTWKVLAVAAMLQRVD +AGQERLDRRIRFDAHQLVSWSPVTERHVGGEMRVDALCAAALEISDNTAANLLLEALGGP +AAITRFARGLDDRVTRLDRYETALNEATPGDPCDTTAPDAMAGDLRRLLLGDALHADSRA +RLLAWMEACRTGDGKLRAGVPAHWRVADKTGSGGYGSSNDVGLLMPPGQRPVVVAVYLTQ +TRVAEAQRHAAIAAVARAIVD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B4C1F70 +-qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYENALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKELTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIAKAAEVVVNAf +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DE6B231 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGFGAALIEHw +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudorhodoferax sp. Leaf267 TaxID=1736316 RepID=A0A0Q4Y0N9_9BURK +--AARAAFTRLEADLGGRLGVFAIDTADGATL-GHRADERFAMASSFKAILAAAMLARSV +QEPALLQRLVRYTERDLLPHSPVTGQHVAQGMTVAALCAATVQYSDNAAANLLLEVLGGP +AALTAYTRTLGDTQFRLDRTEPALNSAQASDPRDTTTPQAMARTLRTLVLGDALPAPQRA +QFKDWLLGNTTGGARIRAGVPAGWAVGDKTGTGNHGAASDIGVVWPPGRAPLVVVVYTWR +EAADAKAREDVIADATRVVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE0F4D8 +--DLAAAFKTLEEKTGARLGVSAHDTGSDSRI-EYRENERFAMCSTFKFLASAAVLARVD +QKQEQLDRMILIKKSDLVAYSPVTEKYVGKPMSIEAICEAAVTLSDNTAGNLMLDTLGGP +KGLTKYARSLGDATFRLDRWETELNEAKPSDARDTITPAAILKDMQKTVLGDALSKSSRD +QLVEWLLGNKTGDKRLRAGLPKDWSVGDRTGTSDSGMANDLAVIWPPDRKPILLAVYLYD +PKGTADSRNTIHKKVAALVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Proteus genomosp. 4 TaxID=1311818 RepID=UPI000D68A444 +--TIEEQLAILEKNSQGRLGVALINTKDNSQI-TYRGDERFAMASTSKVMAVAAVLKESE +KQAGLLNNYITIKKADLVPYSPITEKHLATGMTLAQLSAATLQYSDNTAMNKILDYLGGP +SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEQNAKYRKDVIVKATEIVTKEf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q93A78_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRCEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDEQNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=I7ANY8_KLEPN +--ETLVKVKDAEDQLGARVGYIXLDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAXXXXSLIKHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010135F69 +--------QQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3S8XG03_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSAFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLCKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Carbapenem-hydrolyzing beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=M9T6C6_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QLVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010319F6B +---IDLRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPAKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella genomosp. 5 TaxID=1395608 RepID=UPI000B9E0880 +----QRLLARLEARDGGRLGVSVLDTGSGWAL-AHRSDERFPMCSTFKWVAAAAVLARVG +RGQDSLDRHIRYGATDLVPYSPVTKPQVAQGMTLGALCEAAVVWSDNTAANLMLSTLGGP +PGITAYARSQGDDQTRLDRIEPALNEAQPGDPRDTTTPQAMLRLLRRVLLEGGLEAPQRD +QLTAWLRGCRTGDTRLRAGLPADWVVGNKTGAGEHGTNNDVAVIWPPRGAPILVTAYLTN +SPASRDAQNALLAETARIVAH-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKD8_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHSMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Desulfovibrio fructosivorans JJ TaxID=596151 RepID=E1JVD7_DESFR +--SLTRQIASLEQRAHGHLGVALLNASGALAF-TYRGQERFPFCSTFKFLVAAAVLQKSL +ADPALLDTRIRYGEGDLLSYAPVTRKNVARGMTVAELCAAALQVSDNTAANLLIRQLGGT +RAVNAFARSLGDTAFRLDHLEPDLNAAIPGDPHDTSTPEAMARSMREIALGKVLGPAQRD +RFVAWIKGNTTGDTSIRAGVPPGWTVGDKTGGGAYGTSNDVAVIWPPHGKPIVLAIYFTQ +QQKDAPARRDVLADAARLVVKHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZM32_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKPIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLA---------- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. Acro-835 TaxID=2608357 RepID=UPI00141D8EA2 +-eKIQQQLHQLETQSGGRLGVVLIDSADNTQI-RYRANERFPMCSTSKVMAVAALLQQSE +KNSAVLQQRLAINASDLVNYNPITEKQVGSSMTLAELSAAALQYSDNAAMNLILDHLGGP +AKVTAFAKEMGDSDFRLDRKEPELNSAIPGDPRDTTTPLSMAHSLQKLTLGKALAAPQRE +QLVQWMKGNTTGRQSIAAGLPSGWKVGDKTGSCDYGGTNDIAVIWREKGAPLILTTFFVQ +PQPDAKSRRDVLAAAAKIVTAQy +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTE3_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDLVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium medicae (strain WSM419) TaxID=366394 RepID=A6U720_SINMW +--DVTERLRQLEERTGGRLGVAVLDMETNISF-GYRETERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTIAELCEAAITISDNAAGNLLLESFGGP +QGLTSWLRSIGDNTTRLDRTEPDLNEARKGDPRDTTTPAAMLDTLGKLALGSVLSENGRG +QLVDWLVANETGDARLRAGLPKDWRIGDKTGTSSTGAVSDIALAWPPGRGPLLVAVYTGE +AKAPVSDLNPVFAEIGKIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0C5C1Z0_KLEPN +-----EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=Q6RCP6_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKNGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI0012373A51 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGXLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium variabile TaxID=298794 RepID=A0A0J6T0T2_9RHIZ +--DAAARLAQLERRDGGTLGVEVRDTATGRRF-GHRADERFPMCSTFKALAAAAVLARAD +QGKEDLNRRISYGRDDLLSYAPVTAKHVEAGMTLAELCAAAVVWSDNTAANLMLTTLGGP +EGITAFARAHGDTVTRLDRTEPTLNTAIAGDVRDTTSPAAMVGLLDHVLLGRALSAESRA +RLTGWMHESPTGLKRVRAGLPAEWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG +SPAEPAARDALHAEVGRLIARSf +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella michiganensis TaxID=1134687 RepID=UPI000E6BF6C5 +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLATAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI00037E0EC2 +--DVTERLRQLEERTGGRLGVAVLDMETNISF-GHRETERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTIAELCEAAITISDNAAGNLLLESFGGP +QGLTSWLRSIGDNTTRLDRTEPDLNEARKGDPRDTTTPAAMLDTLGKLALGSVLSENGRG +QLVDWLVANETGDARLRAGLPKDWRIGDKTGTSSTGAVSDIALAWPPGRGPLLVAVYTGE +AKAPVSDLNPVFAEIGKIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A4Q9ZPF8_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTKQTV-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010401029 +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAELGRMVVE-- +>[subseq from] Beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0002184FA7 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDSWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax anthurii TaxID=78229 RepID=A0A328YWW9_9BURK +-eSLEQALGRIESAVGGRLGVAVLDTQTGRQA-AHRGDERFPLCSTFKLLLAAQVLHRVD +QGQERLDRRVTYRRADLVEYSPATASHADAGMTVGQLCEAAVTLSDNTAANLLLASQGGP +LALTAWLRTLGDGHTRLDRGEPELNDVPPGEVRDTTTPWAMVRTVQAIALGPALTEAGRE +QVRAWLVGNRTGDKRLRAGMPAGWRIGEKTGTGPRGTSNDAGLFWPPGRGPVMVSCYLTG +SPASAERRDAAIAEVGALAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010327588 +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GFRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPAKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI0011A94589 +----GNQLAELERKSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ +TQPDLLNKHIKYRESDLLSYAPITRKNLAHGMTVSQLCAATMQYSDNTAANLLIKELGGV +ESVNAFARSIGDQAFRLDRLEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALPAAQRE +QLTLWLKGNTTGAETIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPAQGAPIVMVVYFTQ +REKDAKPRRDVLATATKIVL--- +>[subseq from] Class A broad-spectrum beta-lactamase OXY-4.2 n=1 Tax=Klebsiella pasteurii TaxID=2587529 RepID=A0A5P1KAS4_9ENTR +-dTLQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVFKQSE +SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP +EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=H2ETE8_ECOLX +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITMSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDMRDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYMRD +TPATIAERNQQIAAIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Serratia rubidaea TaxID=61652 RepID=A0A447QJ63_SERRU +-pATLDTIKDAESRLHGRVGYAELDLASGNMMdSYRADERFPMMSTFKVILCGAVLARVD +AGQEQLDRRIRYRQNDLVEYSPVTEKHLAEGMNVGELCHAAITMSDNTAANLLLSTLGGP +SGLTAFLRKTGDSVSRLDRWETALNEALPGDERDTTTPESMARTLHNLLTGDALSAESRR +QLMRWMEMDNVAGPLLRSVLPAGWFIADKTGAGERGSRGIVAALGPDGKPSRIVVIYLTG +TKATMDERNKQIADIGAALINHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus 03BB108 TaxID=451709 RepID=A0A0B5ZH41_BACCE +-qATHKEFSQLEKKFDARLGVYAINTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf85 TaxID=1736241 RepID=UPI000B03100F +-rDLADRFARIEEASGGRLGIGLLDTGSGAHA-AHRGDERFPLCSTFKVLAAGAALARVD +RGEDGLDRRLRYELREVVPYSPVSGPRAGGEMTIAELCEAAVTLSDNTAANLLLGTMGGP +AGLTGHIRRFGDATTRLDRTEPDLNEAAPGDPRDTTTPRAMAETLRHLVLADALSPASRA +LLTAWLVGCRTGDARLRAGLPKDWRIGDKTGSGENDTANDVAVIWPPRRPPLVLTVYLTG +ARTSSEARSATIASVARAVA--- +>[subseq from] Beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0000576766 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWATELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2C3FJ81_BACAN +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNKAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0000519015 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMGTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase SHV-1 n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0000576765 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWATELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9K5K0_KLEPN +--DVQQKLAGLERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSPAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRHVLA---------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7HZA4_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSAFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TSASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. TaxID=376 RepID=A0A525IEQ0_BRASZ +---AEALIAVIEQAAGGRLGVAVIDSGSKRSI-GHRADERFPMCSTFKVLAAGAVLKRVD +AGTERLDRRLPYGPSDLLDYAPIAKSHVGEGMSLADACAAAIQWSDNTAANLVLATIGGP +AGVTDFARSLGDVVTRLDRNEPSLNSAIPGDPRDTTSPYAMARDLQALLLGDALSEASRK +QLEAWMVGNQTGGPRLRAGLPADWGIGDKTGSGDHGVANTIAILRPPGRAPLFVAVYYAE +SDRSMDDRNAVNRDVALVIA--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A5C5A4S4_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYENALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIAKNLKDLTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSNK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. KBS0712 TaxID=2578111 RepID=A0A554S2M4_9BURK +--DAETQLAELERACGGRLGVSGFHTGSGARL-QHRAHERFPLCSTFKLVLAAAVLERSA +TDASLLGRRVSVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP +AAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTSPAAMADTVQRLALGDALGAPQRE +QMREWLLGNTTSTERFLAGVPKGWRVGDKTGAGSYGSTNDVGVLWPPSGAPLVLSVYLTF +PDKDAKGRNDVVASATRIAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus anthracis TaxID=1392 RepID=A0A640LXU0_BACAN +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHY9_KLEPN +-----EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A221SNH6_KLEPN +-----EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=Q6REX6_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKNGASKRGARGIVALLGPNNKAERIVVIYLRD +TPANMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=4 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTE5_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPMIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Phyllobacterium sp. UNC302MFCol5.2 TaxID=1449065 RepID=UPI0012DD7A6D +--DLDAAFKGLDEKTGARLGVAALDTASDSKI-EYRAHERFAMCSTFKFLAAAAVLAKVD +RKEEKLDRVIKYGKGDLVAGSPATGKHVDEGMTLAALCEAAITLSDNTAGNLLLDNLGGP +KGLTQYARSLGDATFRLDRRETELNEAAPGDPRDTITPAHILKDLQKTVLGNALAKSSRD +QLIEWLLANKTGDKRLRGGLPKGWSVGDKTGTSDSGMANDIAVIWPPSRKPILLAVYLYD +PKGTADSRNEIHRKVASLVAE-- +>[subseq from] Beta-lactamase n=6 Tax=Gammaproteobacteria TaxID=1236 RepID=Q9FD24_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. ABP14 TaxID=1892404 RepID=UPI0009F6C565 +-qATHKEFSQLEKKFDARLGVYAINTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BGSC 6E1 TaxID=526970 RepID=C2NHX5_BACCE +-qATHKEFSQLEKKFDARLGVYAINTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVNAf +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI0005ABAC56 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI000949A6B1 +--NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLGRAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGKKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTLPVKELNPIFAEVGRMVVE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF970DE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYKKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +NGYEKALRQLGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q6GWS8_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSREPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERDRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Andreprevotia sp. IGB-42 TaxID=2497473 RepID=UPI00135C3D25 +-------LAALEKQAGGRLGVCAIHTADGVQT-GYRVDERFPFCSTFKLMLASAVLARSV +HATGLLQQRIRYGKRDLVSYSPISEKHLGEGMTVAELCAATIQYSDNAAANLLIQLLGGP +AAVTRFARSIGNNTFRLDRRETALNTAIPGDARDTVTPAAMARSVQALALGNALPATQRE +QLQAWLRGNTTGGKRILAGVPAGWAVGDKTGTGAYGTTNDIGVIWPASGAPIVLAVYYTQ +HGADAKPKDEVIAEATRIVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium TaxID=379 RepID=UPI0003632B26 +--NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTEWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. CF122 TaxID=1144312 RepID=J3BR40_9RHIZ +-dEINRRMEALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQETLERRVVYDQDKLVTYSPETEKHVGGEMSLSELCEAAITLSDNTAGNLLLESFGGP +AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDSMVDTLGNLTLGSALSEPSRD +KLVEWMVANTTGGARLRAGLPDAWKIGDKTGTGNNGSAADIAIVWPPGHGAILVAAYVTQ +AKAPASEINPIFAEVGKIVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. CB01531 TaxID=1718947 RepID=A0A1Q5AT61_9ACTN +------DFARLEAEFDARLGVYAIDTGTGRTV-EHRADDRFGYASTFKALAAAAMLDAAS +--TAELNQVVRYARADLVTHSPITERHVGTGMTLRELGDAAVRYSDNTAANLLLKRLGGP +AGFERALRDLGDQVTDPERIETDLNEAAPGDRRDTSTPRALATDLRAYVLGDALSAEDRA +VLTGWLKGNTTGDKLIRAGVPAGWQVGDKTGSGGYGTRNDTAVIWPPDGAPIVLAVLSSR +DEQDAEYDDKLIAQAAKLTVE-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D358B59 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQHLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNRQIAGIGAALIEHw +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000986911D +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRPIHYSQNDMVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLERWELELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SN1 TaxID=2055158 RepID=A0A2M8T1I8_9BACI +--ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS +--IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP +KGFEEALRQIGDKVTVADRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK +ILTDWMRGNATGDKLIRAGVPKEWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR +DKKDATYDNELIAQAAKVTIN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis subsp. finitimus TaxID=29337 RepID=A0A243GK21_BACTF +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQYS +--TEKLNDVITYTKEDLVDYSPVTEKHVDTGMTIGQIAEAAVRYSDNTAGNILFHQIGGP +KGYENALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. SH7-1 TaxID=2217818 RepID=UPI0011CC72C1 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYKKEDLVDYSPVTEKHVDTGMTIGQIAEAAVRYSDNTAGNILFHQIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000C7AD333 +-----EQITLSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDERLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIAKIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. 18065 TaxID=2681411 RepID=UPI0013586BE8 +--QFAQALEAIEARIQARLGAFVLDTETGMTL-GYRADERFPMCSTFKAIAAAAVLSRVD +AGREDLSRRLHWKKADLIAHSPVTEKHVKAGLTLAELCHAATTVSDNTAANLLLEAIGGP +AGFTAFVRSLGDPVTRIDRMEPALNSAKPGDKRDTTSPAAMAALLKALVLDDALSPTSRD +QLGQWMIANTTGGLKLRAGLPRGFTIGDRTGAGANGTNNVIAVIWPPERKPLVATVFITE +TKTPRPETDPAMAEIGRLLT--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FE02263 +-dDVTERLRQLEERTGGRLGVAVLDTETDISF-GHRETERFAMCSTFKALAAACALARVD +RGKEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +QGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGLVLSQEGRK +RLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE +AKAPLDDLNPVFADIGRIVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia caribensis TaxID=75105 RepID=UPI0007217C87 +--DLARQLARIEAQAGGRLGVAILDTASSKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD +QGKEQLGRKIVYAKEVVVANSPVSGPRAGGDMTVGELCEATITRSDNTAANLLLDSIGGP +AALTAFARSIGDRVTRLDRNEPTLNEATQGDPRDTTTPAAMLADLRALLLGEHLSAASRE +QLTAWLAANKTGDTRLRAGLPKAWRVGDKTGTGERGTSNDIAVVWPEGRAPVLVVAYLTG +ATATATQRDAAIAQVGALVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTB7_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AELTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=5 Tax=Bacillus anthracis TaxID=1392 RepID=A0A0F7RBX2_BACAN +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=5 Tax=Bordetella TaxID=517 RepID=A0A5Q1KKV8_BORPP +--QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAD +RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP +PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQSASRQ +RLADWLLASQTGDTRLRAGLPAGWRIGDKTGAGGHGTNNDIGVIWPRDGAPVLISAYLTQ +SSASREAQNAVLAEVGRIAAH-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis (strain Al Hakam) TaxID=412694 RepID=A0REB0_BACAH +-qATHKEFSQLEKKFDARLGVYAINTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=A0A380PPG3_YERFR +---LGNQLAELERNSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ +TQPGLLDKHIKYHESDLLSYAPITRKNLAHGMTVSQLCAATMQYSDNTAANLLIKELGGV +ASVNAFARSIGDQVFRLDRLEPDLNTALPNDPRDTTTPAAMADSMNKLVLGDALPVAQRE +QLTLWLKGNTTGANTIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPTQGAPIVLVIYFTQ +REKDAKPRRDVLAAATKIVLSH- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pasteurii TaxID=2587529 RepID=A0A5P1KAW0_9ENTR +-dTLQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP +EKVTAFAQNIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=2 Tax=Kribbella sp. VKM Ac-2575 TaxID=2512212 RepID=A0A4R7TFP3_9ACTN +-------FSALEKQYDARLGVYALDTGTGRTV-TYRADERFAYASTSKALSVGALLSDGR +----NLDKLIRYTEADLVTYSPITEKHVATGMTLRQICDAALRYSDNTAANLLFRELGGP +AGLQARLHRLGDRTTHVDRTEPTLNEATPGDIRDTTTPRAIATSLRAYTLGQALPIARRA +LLIDWMRRNTTGDTLIRAGVPKNWKVGDKTGSGGYGTRNDIAVVWPPGRSPIVLAIMSSR +ATADAKYDDALLAAATELVV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. Root482 TaxID=1736543 RepID=A0A0T1X667_9RHIZ +-kSIDERLAALEKRTGGRLGVSVLDKRTNISF-GCRMDERFAMCSTFKMLAGAFALARVD +KGEEDLDRRITYRKADLSPYSPVTEKHTGKKMAVAELCEAAITLSDNTAANLLLESFGGP +AGLTAWLRSIGDPVTRLDRNEPEMNRVKNGDPRDTTTPQAMLETLDRLVLGDVLKPASRE +QLIAWLVANKTGDERLRAGLPSGWTVGDKTGTSGKGELGDVAIIWPSKERPILVSVYIAD +GVGKTKTLNPVFAEIGRMVAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Sinorhizobium sp. M4_45 TaxID=2037901 RepID=A0A2N8K3N7_9RHIZ +--DVTERLRRLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGREVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +EGLTSWLRSIGDETTRLDRTEPELNEARKGDPRDTTTPAAMLDTLGKLVLGPVLSQEGRQ +QLIDWLVANKTGDARLRAGLPKDWRIGDKTGTSMTGAVSDIAVAWPQGRGPILICVYMGE +AKAPLDDLNPVFADIGSIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. YR634 TaxID=1884385 RepID=UPI00089C7381 +--SAEAQLAALESASDGRLGVVGFHTGSGARI-QHRPHERFPLCSTFKLMLAAAVLERST +KDSGLLSRNISYSKADLVAYSPITEKHVATGMTVAAMCAATVQYSDNAAANLLLKVLGGP +PAVTAFARGIGDQAFRLDRTEPELNTSIPGDPRDTTTPAAMADSVQRLALGDALGTVQRD +QLQTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF +PQKDAKGRNDVIASATRIAVA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A4Q9A141_RHILE +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFALARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax caeni TaxID=343013 RepID=A0A1I7H289_9BURK +--SLLSALRGVEQDVGGRLGVAVLDTGTGRLA-AHRGGERFALCSTFKLLLAAQVLHRVD +QGVEHLAQRVAYGQADLLDYAPVTRQHAGGALTVAELCEAAMAWSDNTAANLLLARQGGP +QALTDWLRTLGDPATRLDRNEPALNDVPPGDVRDTTTPEAMARTLQAVALGEVLTPASRE +RLQGWMLGCRTGDQRLRAGMPPGWRIGEKTGTGPRGTSNDIGVLWPPGRAPVVLACYLTG +STADGARRDAALAAVGRSVAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=A0A0T9TEX9_YERFR +----GNQLAELERKSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ +TQPDLLNKHIKYRESDLLSYAPITRKNLAHGMTVSQLCAATMQYSDNTAANLLIKELGGV +ESVNAFARSIGDQAFRLDRLEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALPATQRE +QLTLWLKGNTTGAETIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPTQGAPIVMVVYFTQ +REKDAKPRRDVLAAATKIVL--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B7FDD7_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPAIMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A168KQ64_KLEOX +hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ +QLQRWMVEDKVARPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG +TPATMDERNKQIAAIGATLVRHw +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella TaxID=517 RepID=UPI00052923F3 +--QAQRQLALLEQRHGARLGVQVQDRDSGGAF-SHRADERFPLCSTFKLLAAAAVLARAD +RGDDSLARLIRYGATDIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP +PGLTAYARGLGDRVTRLDRIETALNEARPGDPRDTTTPAAMAGNLERLLLGDALQPASRQ +RLADWLLASRTGDTRLRAGLPSGWRIGDKTGAGGNGTNNDVGVIWPRDGAPVLITAYLTQ +SSASRETQNAVLAEVGRIAAH-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q846Q1_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETERNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Azospirillum halopraeferens TaxID=34010 RepID=UPI000424AE35 +------ALADVERRLDARLGAAILDTQTGRRW-SHRADERFPMCSTFKALACAALLVRVD +AGREDLGQRVRFTAADLVTWSPVTRERAGGDMTLDELCVATMTQSDNTAANLILTRLGGP +SAVTDFARTLGDGVTRLDRMETDLNSAIPGDPRDTTTPAAMLANLQALVTGDALSGPSRE +RFTDWLVANRTGEARLRAGLPGGWRTGDRTGAGANGTNNVVAVIWPPGRAPVFATVYITR +TKATFETTNAAMADIGRALA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00040FD53D +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMIVE-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000B4153B3 +-----EQITLSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDERLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIQHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar andalousiensis BGSC 4AW1 TaxID=527032 RepID=C3G367_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTKQTV-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. JKLM13E TaxID=2582918 RepID=UPI0011064CA0 +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARTD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI0005E1EFBF +----GNQLAELERKSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ +TQPDLLNKHIKYRESDLLSYAPITRKNLAHGMTVSQLCAATMQYSDNTAANLLIKELGGV +ESVNAFARSIGDQAFRLDRLEPDLNSALPNDPRDTTTPAAMAASMNKLVLGDALPATQRE +QLTLWLKGNTTGAETIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPTQGAPIVMVVYFTQ +REKDAKPRRDVLAAATKIVL--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sophoriradicis TaxID=1535245 RepID=A0A2A5KNE4_9RHIZ +--NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KDDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPAAMLDTLGNLTLGSVLTEASCD +RLINWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATVPVKELNPVFAEVGRMIVE-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000808B31E +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKEVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Proteus TaxID=583 RepID=UPI000D6EAFCE +-nTIEAQLSELEKYNQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE +KQAGLLDKNIAIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP +SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEKDAKYRKDIIAKATEIVTKEf +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=A0A2S6YTK7_9XANT +---LRAQWAEIERRTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP +AGVTAFLRGIGDAHTRSDRREPEMNRFTPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus penneri TaxID=102862 RepID=A0A379EM03_9GAMM +-nTIEAQLSELEKYNQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE +KQAGLLDKNIAIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP +SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEKDAKYRKDIIAKATEIVTKEf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sonorensis TaxID=119858 RepID=UPI000497895C +--ALNDAFAKLEDQFDARLGVYALDTGTNQTI-AYRADERFAYASTHKALAVGALLQQKS +--ITDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELCDASIRYSDNTAGNLILKQIGGP +DGFKKSLGKIGDKVTNPERFEPELNEVKPGETHDTSTPKALATSLKAFTIGDALPKEKRM +MLIDWLKRNTTGDALIRAGVPKGWEVGDKTGAGSYGTRNDIAVIWPPKGDPIVLAILSSR +DQKDAEYDDKLIAQAAKEVID-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHZ3_KLEPN +-----EQITLSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDERLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE3A284 +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +RLIAWLVTSTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. PEPV16 TaxID=1820614 RepID=UPI00124CD752 +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=2 Tax=Paraburkholderia ginsengisoli TaxID=311231 RepID=UPI0005A7DD79 +-eAIRARLAQIEATSGGRLGVSIMDTTSGLRA-GLRGDERFPMCSTFKLLAAGAVLTRVD +RGQEDLQRRMVFSASDLVPNSPGTSRHTRELMSVAELCKAALTLSDNTAANLLLASFGGP +AAVTAFARSLGDGVTRLDRIEPELNEAIPGDPRDTTTPNAMLGNLRELVLGDHLSKGSRA +QLLAWLAANETGAARLRAKLPKDWGVGDKTGTGERGTANDIAILWPPGRGPVLVTVYLTE +TDGDATRSNAAIASVGALVVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium anhuiense TaxID=1184720 RepID=UPI000BE7B904 +-dDIQHRIAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSIFKALAAGFVLARVD +KGEEKLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPEAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVTELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=C2VTY7_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPRDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Proteus penneri TaxID=102862 RepID=Q8VTN0_9GAMM +-nTIEAQLSELEKYNQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE +KQAGLLDKNIAIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP +SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEKDAKYRKDIIAKATEIVTKEf +>[subseq from] Beta-lactamase (Fragment) n=179 Tax=root TaxID=1 RepID=J7K3B2_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEI-------- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00048098E2 +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSENHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGNTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=A0A443VPZ4_RAOPL +hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ +QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAERIVVIYLTG +TPATMDERNKQIAAIGATLVTHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=C0L621_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWKTELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTH7_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQISDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0009B90691 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. SH5-2 TaxID=2217834 RepID=UPI0011EBB58D +-qATYKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGILLQQNS +--TEKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFRKIGGP +KGYERALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKGFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8P5B8_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Proteus TaxID=583 RepID=UPI000D689980 +-nTIEEQLSTLEKYSQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE +KQAGLLDKNITIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP +AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPKNHAPLILVVYFTQ +QEQDAKYRKDIIVKATEIVTKEf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. es.034 TaxID=1761763 RepID=A0A2A9BTR6_9BACI +-----HKFMQLEKKFDARLGVYAIDTGTKRTV-VYRPDERFAYTSTYKALAAGAVLQQNS +--MDELDEVITYTKDDLVTYSPITEQHVDTGMTLRGICDAAIRYSDNTAGNLLFQELGGP +DGFENAMRQIGDPVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPEDKRT +ILTDWMKRNTTGDELIRAAVPKGWVVGDKTGAGDYGTRNDIAIVWPPNRDPIIIAVLSSR +DTKDAAYDNELIAKAAKVTVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00143F7F37 +--NIERRLAALEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAAFVLVRAD +KGEENLDRRVSYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=X5D266_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTEGKTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRXDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8VP67_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHFADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLSAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDD4886 +--DLDAAFKGLEEKTGARLGVAALDTASDSKI-EYGAHERFAMCSTFKFLAAAAVLAKVD +RKEEKLDRVIKYGKGDLVAGSPATGKHVDEGMTLAALCEAAITLSDNTAGNLLLDNLGGP +KGLTQYARSLGDATFRLDRRETELNEAAPGDPRDTITPAHILKDLQKTVLGNALAKSSRD +QLIEWLLANKTGDKRLRGGLPKGWSVGDKTGTSDSGMANDIAVIWPPSRKPILLAVYLYD +PKGTADSRNEIHRKVASLVAE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=Q6HIK9_BACHK +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0C5C5N2_KLEPN +-----EQIKLSESQLSGHVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus (strain AH820) TaxID=405535 RepID=B7JPL5_BACC0 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAXAIARNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A6B3JR28_RHILE +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFALARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=UPI000B65D898 +--SLDNQLAELEKSSNGRLGLALIYTGKGTKI-HYRGGQRFPFCSTFKLMLAAAVLGRSQ +SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL +AMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRE +QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVVYFTQ +LEKEAEPRRDVLAAATKIVLAH- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A0S3C5I0_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQYS +--TEKLNDVITYTKEDLVDYSPVTEKHVDTGMTIGQIAEAAVRYSDNTAGNILFHQIGGP +KGYENALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Roseomonas sp. M0104 TaxID=2545983 RepID=UPI001369418E +--ELARTFARIEAAHGGRLGVAVLDTGSGRQA-GHRQDERFPMCSTFKLLAAGAVLARAD +AGQERLDRRVRYGKEELVTYSPVTEKHAGSEMTMAELCEAAITLSDNGAGNLMLDSLGGP +AGLTRWLRGLGDGVSRLDRRETELNEARPGDPRDTTTPAAMLADIRALTLGEALSGAARA +QLRAWLRGCRTGNATLRARLPQGWVVEDKTGSGANGTRNDAGLLCPPGGPPVLVAAYLTG +SPADGAARDAVLAEVGAAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Photorhabdus stackebrandtii TaxID=1123042 RepID=UPI001408FACC +--SLHQQLAELENSTKGRLGVTLINTANGQEL-QYRGNERFPFCSTFKLMLVAAVLHKSM +SQSELLAKHINYRESDLQSYAPIARKNLNQGMSITQLCAATLQYSDNTAANLLIKELGGL +AAVNHFAQGLGDKAFRLDRWEPDLNSAIPDDPRDTTTPAAMAASVKKIVLGETLAEPQRE +QLVVWLKGNTTGNASIRAGAPTGWVVGDKTGSGDYGTRNDVAVLWPPEGSPVVLAIYFTQ +HQKDAESRNDVLASATRLVMEH- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus anthracis TaxID=1392 RepID=A0A2B6C3T5_BACAN +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium phaseoli TaxID=396 RepID=UPI000BE8FA39 +--NVERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD +KGDESLDRRVTYGKEKLVDYSPISEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLYTLGNLTLGSVLAEASSD +KLIAWLVASTTGKERLRAGLPADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia madseniana TaxID=2599607 RepID=UPI0012B43530 +--AIRQRLAQIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKLLAASFVLTRVD +HGQEDLERRIVFSKSDLVPYSPATSQHTRERMSVADLCKAAITLSDNTAANLLLASFGGP +AALTAFARSIGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELLLGERLSSSSRA +QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVTVYLTE +TSGDAARCNAAIADVGALIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia aleksiciae TaxID=263819 RepID=UPI0005DF8DAE +--SLDNQLAELERTANGRLGVALINTANGSKV-QYRGGQRFPFCSTFKLMLTTAVLGQSQ +SLLGLLDKHIRYHESDLLSYAPITRKNLAQGMTVSQLCAATIQYSDNTAANLLIKELGGL +EAINQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASIHKLVLGEALKTPQRE +QLVVWLKGNTTGDATIRAGVPTDWIVGDKTGSGDYGTTNDVAVIWPSQGAPLVLVLYFTQ +RQKDAEPRRDVLASATKIVLSH- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. BAV 3049 TaxID=2654188 RepID=UPI00131E31FF +--DIQQKLADLEKDAGGRLGVALINTADNSQI-LFRGNERFPLCSTSKVMAASAILKQSE +-TKNLMNHRVKIKKSDLVNYNPITEKYVGKEMTLGELSAAALQYSDNTAMNKLISHLGGT +DKVTRFARSIGDKTFRLDRTEPTLNTAIPADKRDTTTPLAMANSLHRLTLGKALGEAQRA +QLVEWMKGNTTGAQSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPPNHAPLILVTYFTQ +PVQDAKARRDVLASAAKIVT--- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI0004489267 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTPPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillus mucilaginosus 3016 TaxID=1116391 RepID=H6NFE0_9BACL +--SAKQPFAQLESEYKARLGVYAVDTGTGRTI-EYRPDERFAYASTFKALACGAVLKAKP +--LEGLEDRVTYTSGELVTYSPVTEKHVSTGMTLRELCDAAIRYSDNTAGNLLLKQLGGP +KGFEAALKEAGDAVTKAERYETELNEAVPGDDRDTSTPRALASSLRAFTLGDALSADKRD +VLTDWLRRNTTGGELIRAAVPEGWVVGDKTGAGSYGTRNDIAVIWPPDGPPIVMAVLSSR +DTKDAAYDNALIAKAAKAALD-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI0004F56FDE +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTPPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillus xerothermodurans TaxID=1977292 RepID=A0A2W1NRK9_9BACL +---TEQSFAQLEQQFAAHLGVFAIDTGTGRTV-AYQADKRFAYTSTFKALAAGAVLLNSS +--TEELDENITYSADDLVTYSPVTEKHVTTGMTLREICDAAVRYSDNTAGNLLLKRLGGP +AGFEAALRQIGDTVTQADRYEIDLNEAVPGDDRDTSTARALATSLQAFALSDVLPENERS +ILTDWLKRNTTGAELIRAGVPQGWTVGDKTGAGGYGTRNDIGIVWPPNGDPIVMAVLSSR +DTQDAAYDNALIAHATKVAVN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AD6B17 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAXAIARNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Bordetella genomosp. 6 TaxID=463024 RepID=A0A261VWQ4_9BORD +--QAQRQLALLEQRHGARLGVQVQDRDSGGAF-SHRADERFPLCSTFKLLAAAAVLARAD +RGDDSLARLIRYGATDIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP +PGLTAYARGLGDRVTRLDRIETALNEARPGDPRDTTTPAAMAGNLERLLLGDALQPASRQ +RLADWLLASRTGDTRLRAGLPSGWRIGDKTGAGGHGTNNDVGVIWPRDGAPVLITAYLTQ +SSASRETQNAVLAEVGRIAAH-- +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=UPI00081CF7A4 +--QAQRQLALLEQRHGARLGVQVQDRDSGGAF-SHRADERFPLCSTFKLLAAAAVLARAD +RGDDSLARLIRYGATDIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP +PGLTAYARGLGDRVTRLDRIETALNEARPGDPRDTTTPAAMAGNLERLLLGDALQPASRQ +RLADWLLASRTGDTRLRAGLPSGWRIGDKTGAGGHGTNNDVGVIWPRDGAPVLITAYLTQ +SSASRETQNAVLAEVGRIAAH-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00102FF756 +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I612_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMVERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCCAA0 +-dEINRRMEALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP +AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD +KLMAWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYLTQ +AKAPVSEINPVFAEVGKIVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum huttiense TaxID=863372 RepID=UPI0003F7ADF7 +-----SRLAKLEAGVAGRLGVEILDSGSGRRW-GYRADRRFPMCSTFKFLAASAVLRRVD +TGAEQLDRRIVYGEDVLVNYSPTTGKHTGGDLSLAQLCEAAITLSDNTAANLMLESMDGP +AGMTRFVRSLGDELTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ +QLAQWLVANQTGDKRVRAGLPKGWKVGDKTGTGRLGTANDVGVVWTEKGAPLLFAVYLTE +NAATDARRDAVHAEVGRLI---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus dielmoensis TaxID=1347369 RepID=UPI000945271E +--QLNREFANLESQFDARLGVYAIDTGTNRTV-SYRPNERFAYASTYKALAAGALLQQSS +--MDQLDELVTYNSEDIVSYSPVTELHVDTGMTLREVIDAAVRYSDNTAGNLLLKKLGGP +EGFEAALRQIGDHTTMADRYETELNAAIPGDKRDTSTPKALAASLEAFAVDDVLPAGKRA +LLTDWMQGNATGDALIRAGAPTDWEVADKSGAGSYGTRNDIAVVWPPNRAPIVIAVLSSR +DTQNAAYDNALIAEAAKIALN-- +>[subseq from] Beta-lactamase n=1 Tax=Serratia rubidaea TaxID=61652 RepID=A0A3S4WU26_SERRU +-pATLDTIKDAESRLHGRVGYAELDLASGKMMdSYRADERFPMMSTFKVSLCAAVLARVD +AGQEQLERRIRYRQNDLVEYSPVTEKHLAEGMNVGELCHAAITMSDNTAANLLLSTLGGP +SGLTAFLRKTGDSVSRLDRWETALNEALPGDERDTTTPESMARTLHNLLTGDALSAESRR +QLMRWMEMDNVAGPLLRSVLPAGWFIADKTGAGERGSRGIVAALGPDGKPSRIVVIYLTG +TKATMDERNKQIADIGAALINHw +>[subseq from] Beta-lactamase n=2 Tax=Bacillus anthracis TaxID=1392 RepID=A0A1J9WHJ1_BACAN +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIVRNLKDFTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNKAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A154IJB8_RHILE +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVSWPPDRGPIVAAVYISE +TTVSAKELNPVFAEVGRMIVE-- +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI0012B8E727 +--AIQQKLANLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRADLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia agricolaris TaxID=2152888 RepID=UPI001292B7F4 +-eAIRQRLAQIEAESGGRLGVSILDTTSGLHT-GLRTDERFPMCSTFKLLAAGLVLTRVD +HGQENLERRVVFSKSDLVPYSPATSRHTRELMSVADLCKAAITLSDNTAANLLLASFGGP +AALTAFARSIGDGVTRLDRNEPALNEATPGDPRDTTTPNAMLGNLRELLLDERLSSPSRA +QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDIAILWPPGRGPILVTVYLTE +TSGDAARCNAAIANVGAVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI0005DC6285 +---LGNQLAELERNSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ +TQPGLLDKHIKYHESDLLSYAPITRKNLAHGMTVSQLCAATMQYSDNTAANLLIKELGGV +ASVNAFARSIGDQAFRLDRLEPDLNTALPNDPRDTTTPAAMADSMNKLVLGDALPAAQRE +QLALWLKGNTTGANTIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPTQGAPIVLVIYFTQ +REKDAKPRRDVLAAATKIVLSH- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDAD570 +-kDIDKQLASLEKRTGGRLGVCVLDTKSNASF-GHRQDERFAMCSTFKALAAAFVLARVD +KGEEKLGRRIAIAKADLHSHSPVAEKHVGDTMTVGELCDAAVTYSDNAAANLLLASFGGP +DGLTAWLRSIGDETTRLDRTEPALNEAKPGDPRDTTTPAAMIRTLGKLLLEDVLSPSSRD +QFTAWLVANRTGGRRLRAGLPAGWTIGEKTGTSGHGEVGDVGFMRPRDGHTILASVYIAE +ATKPMKELEPIFAEVGKLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus camelliae TaxID=1707093 RepID=A0A2N3LLX8_9BACI +--AINQKFVHLEKKFDARLGVYAIDTGTKRTI-AYRSDERFAYASTYKVLAAGVVLQQNS +--IDRLDEVIHYSKDDLVSYSPITEQHVDTGMTLKEICDAAIRYSDNTAGNLLLEKLGGP +KGFEKSLREIGDTITRSDRFETELNEATPGDLRDTSTPKALAKSLKAFTVTNVLPSDKRR +ILTDWMRGNTTGDKLIRAGAPKGWAVGDKSGAGSYGTRNDIAIVWPPHKKPIIIAILSSH +KTKDATYNDELIENAAKVALNAf +>[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=Q1WBU2_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAAL---- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M) TaxID=396598 RepID=B1FU45_PARG4 +--AIRARLEEIEAQSGGRLGVSIVDTTSGLHA-GLHADERFPMCSTFKLLAAGAILARVD +RGEEDLQRRIVYPESELVPYSPATSKHTRERMSIAELCKAAITLSDNTAANLLLQSFGGP +AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNMRELLLGERLKSSSRV +QLLAWLAANETGGARLRAKLPKDWGVGDKTGTGDHGTANDVAIFWPPGRGPILVAVYLTG +TAGDAARNNAAIANVGALVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. CCGE 510 TaxID=1132836 RepID=J6DX46_9RHIZ +-dNIQRRLAALEKRTGGRLGVSVLDTETSISF-NYRGSEAFPMCSTFKALAAGFVLARAD +KGEESLDRRVTYGKEKLVDYSPLSEKHAGTDMTIAELCAAAVTVSDNTAGNLLLESFGGP +AALTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSILTEASSD +RLIAWLVASTTGGERLRAGLPKDWKVGDKTGTGPNGSLGDIAVIWPPNRGPIVAAVYIAE +ATAPVKELNPVFAEVGRMIAE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKF5_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLATIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. b13 TaxID=1761774 RepID=A0A1R3VNU1_9BURK +-----EALAVLEARMGGRLGVCAIDTGSGARL-VHRAEERFPFCSTFKAVLAAAVLARSG +DTPDWLSQRVRYGSADVVSYSPISGQHVGAGMRIDEMCAATLQYSDNTAANQLMKVLGGI +DAVTAFARSVGDATFRLDRWEPELNTAIPGDVRDTSTPAAMADTLRAVMLGNVLRPWQQQ +RLQQWMLGNRTGDKRIRAGVAAQWRVADKTGTGEYGTTNDIGVLWPPERAPIVLSIYFTQ +PQQDAPARDEAIEQATRIVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. IMH TaxID=1267600 RepID=UPI00046ABEC5 +hqATLDKVREAEHLLKARVGYAELDLTSGQLLeSYQADARFPVMSTFKVLLCGAVLARVD +AGQEQLDRRIKYRESDLITYSPVTEKHLAEGMTVSELCSAAITMSDNTAANLLLSTLGGP +QALTAFLRKIGDPVTRLDRWEPALNQALPGDERDTSTPEAMAKTLRQLLTGEVLSVSSRQ +QLMEWMVADKVAGPLIRSVLPEGWFIADKTGAGERGSRGIVAALGPDGKASRLVVIYLTE +SQATMDERNKQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A0B4R7I2_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEP--NTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLILVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia graminis TaxID=60548 RepID=UPI000DEF0CA9 +--AIRARLEEIEAQSGGRLGVSIVDTTSGLHA-GLHADERFPMCSTFKLLAAGAILARVD +RGEEDLQRRIVYPESELVPYSPATSKHTRERMSIAELCKAAITLSDNTAANLLLQSFGGP +AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNMRELLLGERLKSSSRV +QLLAWLAGNETGGARLRAKLPKDWGVGDKTGTGDHGTANDVAIFWPPGRGPILVAVYLTG +TAGDAARNNAAIANVGALVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=UPI00037BF958 +--SAEAQLAELERASGGRLGVAGFNTGSGVRL-QHRAHERFPLCSTFKLMLAAAVLERST +RDSSLLSRNLSYGKGDLIDHSPITEKHVATGMTVAAMCAATIQYSDNAAANLLLKELGGP +ATVTAFARGIGDQTFRLDRTEPELNTSIPGDPRDTTTPSAMSDSIQRLVLGDALGAAQRD +QLKTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF +PQKDAKGRNDVIASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=UPI0002900D41 +--QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAE +RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP +PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQPASRQ +QLADWLLASQTGDTRLRAGLPAGWRIGDKTGVGGHGTNNDIGVIWPRDGAPVLISAYLTQ +SSASREAQNAVLAEVGRIAAH-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009769CC1 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A8TG68_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLSPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAAL---- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTG2_KLEPN +-----EQIKLSESQLSGRVGMIEMDPASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATFGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Proteus sp. G2661 TaxID=2698874 RepID=UPI001379070E +-nTIEAQLSELEKYNQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE +KQAGLLDKNIAIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP +SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEKDAKHRKDIIAKATEIVTKEf +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI0007CC3D0D +--AIHQKLTALEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEP--NTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKNRKEVLAAAAKIVTE-- +>[subseq from] TEM-1 beta-lactamase n=1 Tax=Methylobacterium sp. TaxID=409 RepID=A0A389MUP9_9RHIZ +--ALARRLGEIERASGGRLGVAMRDTGTGLTV-GHRADECFPLCSTFKLLAAGAALARVD +AGRESLERRVPYTAADLVDYSPVTKARVGEGMALGALCEAALTLSDNTAGNLILASLGGP +AGLNAWLRGLGDPVTRLDRIEPDLNEARPGDARDTTTPAAMLADLDRLALGTALTSASRG +TLVAWLRANRTGGARLRAGLPPAWQVGDKTGSGDRGTTNDVGLLWPPGGAPILVAAYLTE +TDAPQERRNASLAEVGRAVASH- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A243BM28_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPEDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B59601 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYQPNERFAFASTYKALAAGVLLQQNS +--TEKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNKLIAEAAEVVVNAf +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009753A7D +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B5992A +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. R339 TaxID=1764273 RepID=UPI000B5306D9 +--NVERRLAALEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGDESLERRVSYGKEKLVDYSPISEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +PGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTETSCS +RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPAKDLNPIFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI000406C23A +--NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRSEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKDLNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. trifolii TaxID=386 RepID=A0A1B8RE65_RHILT +--NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRSEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKDLNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=Q5DUJ5_KLEOX +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKADLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP +EKVTAFALSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia caledonica TaxID=134536 RepID=A0A2Z5MLW6_9BURK +--TIRARLREIEAHSGGRLGVAIVDTTSGLHA-GVHADERFPMCSTFKLLVAGAILARVD +RGEEDLQRRIVYSQSELVPNSPATSKHTRERMSVADLCKAAITLSDNTAANLLLASFGGP +AALTAFARSLGDGITRLDRIEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA +QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIVWPPGRGPILVAVYLTE +TAGDAARCNAAIASVGALVAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. C03 TaxID=1945858 RepID=A0A1V3Q011_9GAMM +---AQARLAALERQHGGRLGVAILDTGNGRRI-GHRADERFLMCSTFKLLAVAAVLARVD +REAERLDRRIVFDQEAVLAYAPVTSHRVGAPMTVAELCQAAITVSDNTAANLLLTSLGGP +TAVTAYVRSLGDGVTRLDRIEPELNVASPGDLRDTTTPSAMLADLSTLLLGDALSAASRE +QLAAWLRATSTGTEQLRAGMPAGWRVGDKTGSGAQRETNDIAIIWPPQRKPLLVTAYYAG +SAASNDERHAVLAEVGRIAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q83W48_PSEAI +--ETLVKVKDAEDKLGVRVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLI--- +>[subseq from] Beta-lactamase KPC-8 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B6V684_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas bohemica TaxID=2044872 RepID=UPI000DA61DEC +---IKQKLAELELRHGGRLGVAILDTASQRLI-DHRGNERFALCSTFKALAVAHVLARVD +RKEEDLSRMIVYGQEQLVTYSPITEKHTGEGLSVGSICEAAITLSDNTAANLLLDSFGGP +ESLTDWLRSTGDEVTHLDHREPKLNENRPGDPRDTTTPVAMLHSLRRLALGDALSDASRD +QLIAWLVSNKTGDQKLRAGLPKGWRVGDKTGSGSNNAGNDVAVIWPPNRPPLIVTVYYTD +SKASSEQINGVMAEIGKWVA--- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001261AD9B +-----EQIKLSESQLSGRVGMIEMDLASGRTLtTWRADERFPIMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B8YHZ7_KLEPN +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTSHTLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATIAERNQQIARIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3M0DDG8_KLEPN +-----EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ +QLLQWMVDDQVAGPLLRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus lautus TaxID=1401 RepID=A0A328WCW7_PAELA +--------------DGIELYVGVQDLSGGGKI-QAGSSNVYYAASTIKMAIVTALMQDIE +AGKYALEQTVQVKPEQVVGGAGSLKDKFPQEITIERLAGLMITQSDNTATNALIDLL-GF +ERINAFIDEQGFKTMQLGRKMMTPAKS--PAADNYVNGEELLTLLERIYTGEIVSAQSRD +QILAWMKAQEV-KTKFGAALP-GKPIAHKTGELGD-VSHDIGYFLVPGRE-VAVTVLTKV +NKKAQELGNPVVQRAAKAVYNY- +>[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus lautus TaxID=1401 RepID=A0A328WCW7_PAELA +-----------AEEKGIRVSVGLKDLSDDREL-LLGSRQSYMPASTIKMALVSALMKEVD +AGRLTLEQKVKVEQEDVVGGTGSLQKETPQDVTIERLARLMITQSDNTATNVLIDVV-GL +NKVQALLDELGLDVMHLGRKMFAAA--PTPEQDNYINAEDLVHLLANIHSGEFLSENSRD +QIIDWMKAQEV-DTKFGAALP-DAPIAHKTGENAN-VTHDAGYFLQPGR-EIAISVLTEV +TTEAQAIGNPVVQEIAKAVYQ-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q7X5A6_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR +HLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus glycinifermentans TaxID=1664069 RepID=A0A0T6BTP5_9BACI +----SNQFSRLEDQYDARLGVFALDTGTNKTV-TYRADERFAYASTHKALAVGALLKQTS +--IADLNQRITYTRDDLVNYNPITEKHVDTGMTLKELCDASIRYSDNTAGNLILKQIGGP +SGFKQSLREIGDNVTNPERIEPDLNEVKPGETHDTSTPKALAKSLQAFTVGDALPKEKRE +MLVDWLKRNTTGDALIRVGVPKGWEVADKTGAGSYGTRNDIAVIWPPKGDPIVLAVLSSR +DKKDADYNDKLIAEAAKEVIK-- +>[subseq from] Beta-lactamase n=2 Tax=Methylobacterium haplocladii TaxID=1176176 RepID=A0A512IMI4_9RHIZ +--SAEEAFARIEAAVGGRLGVATLDTGSGRRL-SYRAEARFPLCSTFKLLAAAAILAQVD +KRREQLDRRVPYTTADLVDYSPTTKIRAAEGMPLADICEAAITLSDNTAGNLMLAQIGGP +AGLTAFLRAGDDAVTRLDRIEPDLNEALPDDPRDTTSPRAMVSDLERLVVGDALSAGSRG +QLTAWLLANQTGGTRLRAGMPRDWRVGDKTGTGDRGTANDVGILLPPGGAPILAAVYLTE +STGSAEQRNAAIADTARTIVR-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces kanamyceticus TaxID=1967 RepID=A0A5J6GAM9_STRKN +--DVRRRLRELEKGYPGRIGVHALHTGTGATV-AYRADERFAIASTFKVLAAAAILRRAR +EEPGLLDVLIRYGRDDLVEYSPRTEMHLETGMTVRELCDATLTYSDNSAANLLMRRIGGP +TGITEFARSIGDSRTRLDRWETDLNTNIPGDRRDTTTPAAMTENLRRLVLGDALHPLDRD +QLIRWLLENTTGDKRIRAGLPEGWRVGDKTGSPAYGGVNDVAVAWPPKRAPLVVSVYTTR +LDPDTPGEDRIAEDITRIVVD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKG6_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKI1_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKB5_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKH2_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007CC9620 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFLMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=bacterium M00.F.Ca.ET.191.01.1.1 TaxID=2563911 RepID=A0A4S0JKF0_9BACT +--AIRARLAEIEAQSGGRLGVSIVDTTSGLHA-GLRADERFPMCSTFKLLAAGAVLARVD +RGEENLQRRIVYSQSELVPNSPATSRHTRERMSIAELCKAAITLSDNTAANLLLQSFGGP +AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRALVMGEQLSSTSRV +QLLAWLAANETGGARIRARLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILLAVYLTG +TAGNAARSNAAIADVGALVVE-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2B82CA +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGH +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=Q6W9D3_RAOPL +hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ +QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG +TPATMDERNKQIAAIGATLIRHw +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=UPI0005F7C708 +hdATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPGERFPMMSTFKVPLCAAVLARVD +AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAGLCAAAITLSDNTAANLLLASVGGP +QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLTGSVLSAASRQ +QLLSWMVDDKVAGPLLRSTLPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMEERNRQIAGIGETLVKHw +>[subseq from] Beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=Q6W7F2_RAOPL +hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ +QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG +TPATMDERNKQIAAIGATLVTHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0G8EQ15_BACCE +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGEVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWKVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter freundii TaxID=546 RepID=A3FFR5_CITFR +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARLQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=H9AXM1_ACIBA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSRNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDCWEPELNEAIPHDERDTTMPAAVATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A444P8M7_RHILE +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALASAFVLARAD +KGEENLDRRVSYSKEKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +KLIAWLVESTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora mirobrigensis TaxID=262898 RepID=A0A1C4YY61_9ACTN +----DNEFRQLEEKFDARLGVYAIDTGTGRTV-RYRADERFAYASTFKALAAAEVLDETT +--DAELDRVVRYSADDLVTYSPITEQHVDDGMTLRAIADAAVRYSDNTAGNLMLRRLGGP +QKFEKELREIGDKVTDPARWETALNEARPGDRRDTSTPRAMAGSLRAYAVGNALEPADRA +VLNGWLRGNTTGGELIRAGVPDGWVVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEKDADYDNVLIAEATKVVLAGw +>[subseq from] Beta-lactamase SHV-4 n=2 Tax=Enterobacteriaceae TaxID=543 RepID=BLA4_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQL +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=Q4L202_RAOPL +hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ +QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG +PPATMDERNKQIAAIGATLVTHw +>[subseq from] class A beta-lactamase n=1 Tax=Proteus TaxID=583 RepID=UPI000D69BD2C +-nTVEEQLNTLEKYSQGRLGVALINTEDNSQI-IYRGEERFAMASTSKVMAVAAVLKASE +KQAGLLDKNITIKKSDLVAYSPITEKHLTIGMTLAELSAATLQYSDNTAMNKILDYLGGP +AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVIYFTQ +QEQDAKYRKDIIAKAAEIVTK-- +>[subseq from] SHV family class A beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000BDEEFE1 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLAPVGGP +AGLTAFLRQIGDTVPRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. JPY366 TaxID=668820 RepID=UPI00048EC465 +--AIRARLEDIQAQSGGRLGVSIVDTTSGLHA-GLHADERFPMCSTFKLLAAGAILARVD +RGEEDLQRRIVYSKSELVPYSPATSKHTRELMSVAQLCKAAITLSDNTAANLLLQTFGGP +AGLTAFVRSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELVLGERLSSASRA +QLLAWLAANETGGARIRAKLPKNWGVGDKTGTGDHGTANDVAILWPPGRGPILVAVYLTE +TAGDAARGNAALANVGALVVE-- +>[subseq from] Beta-lactamase n=8 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q939H4_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLSAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase SHV-3 n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=BLA3_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQL +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Rhodoferax koreense TaxID=1842727 RepID=A0A1P8JQI2_9BURK +--RFRQRMQAIEQASGGRLGVAVRDTHSGAAF-AHRGGERFPLCSTFKFLAAAQVLARVD +SGAEQLDRRIAVLASDLVPYAPVTQPRVGGEMTVAELCDAAVTLSDNVAGNLLLRSFGGP +AALTAYLRGLGDGQTRLDRIEPELNQALPGDPRDTTTPEAMLQTLHRIVLGDALSPPSRA +QITRWLVDNKTGDRKIRAALPAGWRVGDKTGAGAFGTNNDIAVLWPPGRLPVLVTAYLTD +TSADQAVRDQALAEVGRLVV--- +>[subseq from] Beta-lactamase n=2 Tax=Citrobacter TaxID=544 RepID=A0A4P7Q172_CITFR +-pTTLNKVKEAESQLTARVGYAELDLTSGEILeSYRLQERFPMMSTFKVLLCGAVLARVD +AGKERLDRRIPFSQRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGP +QGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILTTTSQQ +QLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYVTE +SQATMEERNRQIAGIGATLIQHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B0FP98_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGENVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTNQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A164DHN1_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIAKNLKDFTVGNALPDHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis nigrescens TaxID=381445 RepID=UPI000369B36A +---IYRELRALEQRHSARLGVYAVNTKTGATV-AYRAQERFPLCSTFKTLAAAAVLRDLD +RDGEFLDKVIRYTEKDLVNGSPITKDHVGEGMRVGDLCAAAICYSDNTAGNLLLRQLGGP +GGVTGFCRSIGDHRTRLDRWEPELNTAIPGDPRDTTTPGAIGRDYGRLVLGDALDPGDRA +RLTGWLKANTTSGKRFGAGLPDDWELGDKTGSGDYGTTNDVGVAWTADGTPIVLAVLSTK +HTQDAAYDDLLIADTARL----- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RGY2_9BACT +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=Q2VCD9_RAOPL +hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGSVLSSASQQ +QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG +TPATMDERNKQIAAIGATLIRHw +>[subseq from] Beta-lactamase n=2 Tax=Bacillaceae TaxID=186817 RepID=A0A090YAH1_BACMY +--ATHREFAQLEKKFNARLGVYAIDTGTNQAV-TYRPNERFAYASTYKALAAGAVLQQNS +--IDKLDEVITYTKDDLVEYSPITEKHVDTGMTLGEIAEAAIRYSDNTAGNLLFKKLDGP +KGFEKALRQIGDKVTMADRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPTDKRK +ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR +DKEDATYDNELIAQAAKVIVN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1Y6AX36_BACCE +---TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQKNS +--TEKLNEVVTYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTKSDRLETELNEAIPGDKRDTSTAKAIATNLKDFTVGNALPDQKRN +ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAAYDNQLIAEAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium BLR1 TaxID=506512 RepID=B5L5U5_9BACT +-qDASAQLAALEAASGSRLGVVGFNTATGARV-QHRAEERFPFCSTFKLMLAAAVLERSA +KEGDLLARRVNYSKGDLVSYSPITEKNVATGMTVAELCAATVQYSDNGAANLLMKILGGP +SAVTAFARASGDEVFRLDRWETELNTAIPGDLRDTTTPAAMAASVQRLVLGNALGAAQRE +QLKTWLLGNTTSTQRFLAGVPAGWKVGDKTGSGSYGTTNDVGVLWPPAGAPLVLAVYLTF +PQKEAKGRSDVVASATRIAVS-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas mosselii TaxID=78327 RepID=A0A2V4KK02_9PSED +---LRQAMQQLEAASGSSIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHRSV +SEPGLLARRIAYGAEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP +PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGMTLQRLLLTDGLPAAAQQ +QLQAWLKGNTTGDTRIRAGVPKDWVVGDKTGSGDYGVANDVAVIWPKDRAPWILVVFSRG +TKQDAPWNSETIAAATRIVVEAw +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella TaxID=160674 RepID=UPI00062BE110 +hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGSVLSSASQQ +QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG +TPATMDERNKQIAAIGATLVTHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A142K3H5_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIAEKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEH- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. 250J TaxID=1478142 RepID=A0A0L6FU89_9PSED +-nSLRQAMQQLEAASGSSIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHRNE +VEPGLLARRIAYGTEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP +PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGMTLQRLLLTDGLPAAAQQ +QLQAWLKGNTTGDARIRAGLPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRS +TKQDAPWNSETIAAATRVVVEAw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0014411CFB +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARTD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000D745CF0 +-----EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ +LLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. BK151 TaxID=2512132 RepID=A0A4R1ZKR6_9BURK +--SAEAQLAELERASGGRLGVAGFNTGSGVRL-QHRAHERFPLCSTFKLMLAAAVLERST +RDGSLLSRNLSYGKGDLIDHSPITEKHVATGMTVAAMCAATIQYSDNAAANLLLKELGGP +ATVTAFARGIGDQTFRLDRTEPELNTSIPGDPRDTTTPSAMSDSIQRLVLGDALGAAQRD +QLKTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF +PQKDAKGRNDVIASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Competibacteraceae bacterium TaxID=2053538 RepID=A0A433I2A2_9GAMM +----QEQLAQLEKTAGGRLGVCAIDMSHGAQI-SHRGDERFPLCSTFKVILVAAILTRSS +RVDGLMQRRVYYKRSDLAAYSPMTERHIVDGMTVADLCAAALQYSDNTAANILIGIVGGP +AAVTEYARSIGNAEFRLDRWETDLNSSTPGDLRDTATPASMARSLQALSCGDALPPAQTQ +QLNEWLRGNTTGAKRIRAAVPADWSVGDKTGSGDYGVTNDIAVLWPPQRQPIVVALYYTQ +DEPKAPWRDEVIAAAARIVVDGf +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. BK370 TaxID=2512126 RepID=UPI0010526D06 +--SAEAQLAELERASGGRLGVAGFNTGSGVRL-QHRAHERFPLCSTFKLMLAAAVLERST +RDGSLLSRNLSYGKGDLIDHSPITEKHVATGMTVAAMCAATIQYSDNAAANLLLKELGGP +ATVTAFARGIGDQTFRLDRTEPELNTSIPGDPRDTTTPSAMSDSIQRLVLGDALGAAQRD +QLKTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF +PQKDAKGRNDVIASAARIAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7HZC1_KLEPN +-----EQIKLSESQLSGSVGMVEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. (strain ATCC 39149 / NRRL 15099 / SCC 1413) TaxID=219305 RepID=C4RM91_MICS3 +-----AELAALERRFDARLGVYAVDTGTGRTL-AHRADERFAYASTFKALAAGALLAATS +--DAELDRVVRYERADLVPHSPVTEQHVAGGMTLRAVADAAVRYSDNTAANLMLAELGGP +AGFERALRGIGDTVTDPARTETSLNEAAPGDVRDTSTPRAMATSLRAYALGDALSAADRT +VLVDWLRRNTTGATLIRAGVPAGWQVGDKTGAGGYGTRNDIAVLWPPDGAPIVLAVMSRR +AAKDAQPDDALIAEAARVTVD-- +>[subseq from] Beta-lactamase KPC-6 n=4 Tax=Enterobacterales TaxID=91347 RepID=B2CYF2_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=A0A640J386_9BURK +--DAETKLAELERACGGRLGVSGFHTGSGARL-QHRAHERFPLCSTFKLVLAAAVLERSA +TDASLLGRRISVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP +AAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPAAMSDTVQRLALGDALGAPQRE +QMREWLLGNTTSTERFLAGVPKGWRVGDKTGAGSYGSTNDVGVLWPPSGAPLVLSVYLTF +PDKDAKGRNDVVASATRIAVK-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0012EA6ADA +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGT +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRNLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI0011A34345 +----GNQLAELERKSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ +TQPDLLNKHIKYRESDLLSYAPITRKNLAHGMTVSQLCTATMQYSDNTAANLLIKELGGV +ESVNAFARSIGDQAFRLDRLEPDLNTALPNDPRDTTTPAAMAGSMNKLVLGDALPAAQRE +QLTLWLKGNTTGAEAIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPTQGAPIVMVVYFTQ +RENDAKPRRDVLAAATKIVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium laguerreae TaxID=1076926 RepID=UPI0014418288 +--NIEHRLATLEKRTGGRLGVSVLDTETSISF-GYRGSESFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGADMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=Q2VCE4_RAOPL +hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ +QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG +TPATMDERNKQIAAIGATLITHw +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2S1R3D7_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEHLGRRIHYSQNDLVESPPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDEANRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I622_KLEPN +-----EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=H9CTU8_KLEPN +-----EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B432296 +---TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQKNS +--TEKLNEVVTYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTKSDRLETELNEAIPGDKRDTSTAKAIATNLKDFTVGNALPDQKRN +ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAAYDNQLIAEAAEVVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI000CEDB9BB +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRHEPEMNRYAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=A0A1E7U0B5_9BURK +--DAETQLAELERACGGRLGVSGFHTGSGARL-QHRAHERFPLCSTFKLVLAAAVLERSA +TDASMLGRRISVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP +AAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPAAMSDTVQRLALGDALGAPQRE +QMREWLLGNTTSTERFLAGVPKGWRVGDKTGAGSYGSTNDVGVLWPPSGAPLVLSVYLTF +PDKDAKGRNDVVASATRIAVK-- +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=UPI000F49C8C2 +heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD +AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAGLCAAAITLSDNAAANLLLASVGGP +QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPLAMAKTLHNLLTGSVLSAASRQ +QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMDERNRQIAEIGETLVKHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium laguerreae TaxID=1076926 RepID=UPI0013BCB733 +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSESFPMCSTFKALAAAFVLARAD +KGEENLDRPVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Chromobacterium sp. MWU13-2610 TaxID=2077146 RepID=A0A2K4MR30_9NEIS +----EQKIARLERDFGGQIGVYALDTGSGATV-SYRADERFPLCSSFKGFLAASALAHSQ +SKPGFLDQTLHYGKEDLIVWSPISEKHQASGMTVAGLCAATVQYSDNAAANVLMKQLDGP +AGLTAFMRSIGDSTFRLERWEPELNTAIPGDARDTSTPRAVAESLQKLTLGTALAAPQRQ +QLVDWLKGNTTGNQRIRAAVPAGWSVGDKTGTCGYGTANDYAVIWPTGRAPIVMAVYTRA +SKKDIKHSDAVIADAAKAALE-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=A0A250DIU2_9BURK +---AETQLAELERACGGRLGVSGLHTGSGARL-QHRAHERFPLCSTFKLVLAAAVLERSA +TDASLLGRRISVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP +SAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPAAMSDTVQRLALGDALGAPQRE +QMREWLLGNTTSTERFLAGVPKGWRVGDKTGAGSYGSTNDVGVLWPPSGAPLVLSVYLTF +PDKDAKGRNDVVASATRIAVK-- +>[subseq from] Beta-lactamase n=9 Tax=Enterobacterales TaxID=91347 RepID=A0A0G3QXS5_KLEOX +-----EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia bonniea TaxID=2152891 RepID=UPI001290B981 +---ALTQLQELERSSGGRLGVLALDLTGHVPL-SYRADERFPLCSTFKTMLAAAILQRSR +SAPSLLAQQVQYRSGELASYSPVTRQHVEDGMSVGALCAAALQYSDNTAANLLLKILGGP +AAVTAFARSLGDNLFRLDRWEPELNSATPGDPRDTSTPAAMAHSLQRLLLGDALGAAQRT +QLRDWMQANTTGAARIHAGVPPTWQVADKTGTGDYGTTGDIAVLWPPGMPPVTLALYFTQ +PGKDAKARDDVLAAATRVLVS-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. JKLM12A2 TaxID=2583231 RepID=A0A5R9P7D0_9RHIZ +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTGMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPAHWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. BK376 TaxID=2512149 RepID=A0A4R3G5Z3_9RHIZ +--DADKQLAELEKKTGGRLGVAVLDTETNISL-GYRENERFFMCSTYKALAAGFVLARVD +KGEEKLDRRVMFGKDALVSYSPVTEKHAGTDMTVAELCEAAITMSDNTAGNLLLDSFGGP +SALTAWLRATGDDETRLDRREPDLNEAKKGDLQDTTTPDSMLDTIGLLTLGDTLSEASRN +HLIDWMVADKVGDARLRAGVPKDWKIGDKTGTGNNGALGDIAVIWPPDRGPFIVAVYIAE +ATAPMKDLNDVFAAVGKLV---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. N122 TaxID=1764272 RepID=UPI000B5A85A4 +--NIEKRLAALEKRTGGRLGVSVLDTQTSISF-NYRGDEAFPMCSTFKALAAGFALARAD +KGEESLDRRVTYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +KLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPAKELNPVFAELGRMIVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I7ABU5_ECOLX +--DVQQKLAELERQSEGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAE----------------- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. OV446 TaxID=2135496 RepID=A0A2V3RBQ2_9BURK +--TIRARLREIEADSGGRLGVAIVDTTSGLHA-GLHADERFPMCSTFKLLVAGAILARVD +RGEEDLQRRIVYSQSELVPNSPATSKHTRERMSVADLCKAAITLSDNTAANLLLASFGGP +AALTAFARSLGDGITRLDRIEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA +QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIMWPPSRGPILVAVYLTE +TADDAARRNASIADVGALVAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=A0A2S1LUS9_KLEVA +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMEDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A5B3HZY6_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar guiyangiensis TaxID=180871 RepID=A0A242XUQ6_BACTU +-qATYKEFSQLEKKYDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVINYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDNRDTSTAKAIATNLKEFTVGNALPDHKRN +ILTDWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKDAPYDNQLIAEAAEVIVN-- +>[subseq from] Beta-lactamase n=1 Tax=Stappia sp. BW2 TaxID=2592622 RepID=A0A5D0W7B5_9RHOB +---LDKTVADAENRLSARIGVAVLDTETGKTW-THRADERFPLNSTFKAFLCAALLEKGE +QGDLQPEHRVKIRKEDLVTYSPVTEKKIGSGMTYLELCDAAITISDNAAANLVLEAVGGP +QGLTEYLRSIGDTITRLDRAEPTLNEGQPGDDRDTTTPAAAVATLQKLVLGDALSPTART +RLTDWLLDNQVGKATLRAGLPEEWPVADKTGAGGNGSRNNIGVIWPDDRKPVVIAVYITQ +TAASFDDRNRAIADIAAALAD-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Yersinia TaxID=629 RepID=UPI00067091B8 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. OK233 TaxID=1882795 RepID=A0A2C9BXP5_9BURK +--AIRQRLAQIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKLLAAGFVLTRVD +HGQEDLERRIVFSKSDLVPYSPATSQHIRERMSVADLCKAAITLSDNTAANLLLLSFGGP +AALTAFARSIGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELLLGERLSSSSRA +QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVTVYLTE +TSGDAARCNAAIANVGALVVA-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000FA45589 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELL-LASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. J15 TaxID=2035450 RepID=A0A2A6JQB8_9RHIZ +--NVERRLAALEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD +KGDESLDRRVSYGKEKLVDYSPISEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +PGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTETSCN +RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPAKDLNPIFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. N4311 TaxID=1703972 RepID=A0A235ATA3_9RHIZ +--NIEKRLAALEKRTGGRLGVSVLDTQTSISF-GYRGDEAFPMCSTFKALAAGFALARAD +KGDESLDRRVTYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +KLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPAKDLNPVFAEVGRMIVE-- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0A1C3V8_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPGSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QLVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7HZR2_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVVLLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. BH2 TaxID=2528958 RepID=A0A4Y7QSG0_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTKQTV-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia bryophila TaxID=420952 RepID=A0A329CL71_9BURK +--TIRRRLAQIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKVLVAGAVLTRVD +RGQESLERRIVFSQRDLVPNSPATSRHTRERMSIAELCKAAITLSDNTAANLLLATFGGP +AGLTAFARDLGDGITRLDRIEPTLNEAIPGDPRDTTTPNAMLGNLRELVLGEHLSSSSRA +QLLAWLVANETGGARLRAKLPRDWGVGDKTGTGDHGTANDIAILWPPGRGPVLVVVYLTG +TNGDAARCNAAIAEVGALVVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. 17Sr1-39 TaxID=2583531 RepID=A0A5C4LEG6_9RHIZ +--DAAARLAQLERRDGGRLGVEIRDTATGRRF-GHRADERFPLCSTFKAIAAAAVLARAD +KGQDDLNRRMTYGRDALLSYAPVTSKHVETGMTLAELCAAAVVWSDNTAANLMLDTLGGP +AGITDFARAHGDTVTRLDRTEPTLNTALPGDPRDTTSPAAMVGLLDHVLLGRALSGESRA +RLLGWMQESPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG +SPAEPAARDALHAEIGRLIARSf +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella sp. T31 TaxID=2054594 RepID=UPI000C292501 +-eATVAMVKHAESQLQGRVGYAELDLASGQLLaGYRPDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTAGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTAFLRHSGDQTSRLDRWETELNEARPGDVRDTTTAQAMARTLRNLLTGRVLSPASQQ +QLLHWMVEDKVAGSLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAGRIVVIYLTG +TPASMDERNKQIAAIGKTLVAHw +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007CBC2DC +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=A0A0P0IGT7_KLEVA +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] class A beta-lactamase LEN-30 n=1 Tax=Klebsiella TaxID=570 RepID=UPI0009BB5352 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D613_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-23 n=3 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2Z4BW68_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. NEAU-SY24 TaxID=2292265 RepID=UPI000E23377C +--AIEAELASIEQGVGARLGVAIHDLETGLRT-GRRCSERFPMCSTFKLMLAASVLARVD +RRQEELERRIVFGADRIEQYAPVTRQHVGAPMSVAELCDAAVTMSDNTAANVLLDTIGGP +PGFTAFMRGLGDTVTRLDRTEPTVNTATPGDPRDTTTPVAMLGSLRKVLLGDALSPAARA +QLLAWGAGNRVGDARLRAGVPRDWRVADKTGTGERGTTNDIGILWPQDRAPILVTVYLTE +TDAPDRAREAAIADVARTVARH- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A384WDR9_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQRERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia dilworthii TaxID=948106 RepID=UPI00040F9DB2 +--AIRARLKQIEAESGGRLGVSIVDTASGLHA-GLHADERFPMCSTFKVLAAAAILARVD +RREEDLQRRIVYSQSELVSNSPATSKHTRERMSVAELCKAAITLSDNTAANLLLASFGGP +AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELVLGERLASSSRA +QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVAVYLTG +TAGNAARCNAAIANVGALVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000E1F8026 +---LRAQWAEIERRTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGQLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP +AGVTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola subsp. tropicalensis TaxID=2489014 RepID=A0A455LP13_KLEVA +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITMSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDMRDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] LEN family class A beta-lactamase n=1 Tax=unclassified Klebsiella TaxID=2608929 RepID=UPI000C2993E0 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITMSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDMRDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola subsp. tropicalensis TaxID=2489014 RepID=A0A455LP11_KLEVA +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITMSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDMRDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2DBB64 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTIPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=Q8L2F9_SALTM +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAELSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTSELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERSRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. L1A1 TaxID=2502246 RepID=UPI0010F6A2AF +--SFEDALAEIEVRSGGRLGVAVLDTGSGELT-GRRIDERFPLCSTFKALAAAAVLARVD +AQEERLDRRVVFGREALVPYSPVTEPRIGGSMSLAELCEAAVIRSDNTAGNLLLQAIGGP +AGLTAQLRAFGDDVTRLDRTEPTLNEALPGDPRDTTSPGAMARTLAGLTLGSALTQPSRD +RLTAWLLDNRTGGKRLRAGLPSGWRIGEKTGTGEYGTTNDVGVIWPPEGAAQVVAVYLTA +TDRPLSEREDAIAAVARAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Proteus sp. G2669 TaxID=2698881 RepID=UPI001412B6B3 +--TIEEQLTILEKNSQGRLGVALINTKDNSQI-TYRGDERFAMASTSKVMAVAAVLKESE +KQAGLLNNYITIKKADLVPYSPITEKHLATGMTLAQLSAATLQYSDNTAMNKILDYLGGP +SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEQNAKYRKDIIVKATEIVTKEf +>[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia caribensis TaxID=75105 RepID=A0A142YTR5_9BURK +--DLARQLARIEAQAGGRLGVAILDTAGTKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD +QGKEQLGRKIVYAKEVVVANSPVSGPRAGGDMTVGELCEAAITRSDNTAANLLLDSIGGP +AALTAFARSIGDRVTRLDRNEPSLNEATQGDPRDTTTPAAMLADLRALLLGEHLSSASRE +QLTAWLAANKTGDTRLRAGLPKAWRVGDKTGTGERGTSNDIAVVWPEGRAPILVVAYLTG +ATATATQRDAAIAQVGALVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A286S471_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVDLLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase SHV-24 n=1 Tax=Escherichia coli TaxID=562 RepID=BLA24_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARGTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I6M7_KLEPN +-----EQIKLSESQPSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=G3F057_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALD-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0011EAFCE8 +-----EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A3R9EF50_BACSP +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKC7_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=UPI0011A3E0F9 +--SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLAAAVLGRSQ +SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL +AMVNQFARSIGDQTFRLDRWEPELNTALPNDPLDTTTPAAMAASVNKLVLGDALAAPQRE +QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVVYFTQ +LKKEAEPRRDVLAAATKIVLAH- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI000F8CBD76 +---LRAQWAEIERRSGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVTIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] UPI001156C740 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI001156C740 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI00025002AB +--AIHQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKADLVVWSPITEKYLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP +EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRT +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodospirillales bacterium 39-66-50 TaxID=1970570 RepID=A0A259MSY3_9PROT +----VSSLRELERRNGGRLGVAMFDTASGRRV-AYRGDERFPMCSTFKFLAAALMLARVD +RGEESLDRRIVFAASDLVTYSPATREHGGPAMTVDAICAAAVTLSDNTAGNLMLASFGGP +AGLTAFARVLGDTVTRLDRIETALNEGTPGDPRDTTSPLAMLATMQKLVAGDVLSSASRE +RLIGWLVANKTGDKRLRAGVPAAWRIGDKTGTGGNGSANDIAVAWPPGRAPVFVTAYYTG +STISDEARSAVIAEAGRIAT--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKF7_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDSKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. CF394 TaxID=1500304 RepID=UPI00055BFDA3 +-dEINRRMEALEKEIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQENLERRVVYEPDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP +AELTKWVRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD +KLVEWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYVTQ +AKAPLSEINPVFAQVGKIVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010396F36 +--NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWVRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKDLNPVFAEVGRMIVE-- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase KPC-7 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B3GS81_KLEPN +----AEPFAKLEQDFGGSIGVYAIDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI001297FD9F +--DVTERLRQLEERTGGRLGVAVLDMETNISF-GHRETERFAMCSTFKALAAACALARVD +RGEEKLERRITFGKEVLLPHSPVTEKHVGGNMTIAELCEAAITISDNAAGNLLLESFGGP +QGLTSWLRSIGDNTTRLDRTEPDLNEARKGDPRDTTTPAAMLDTLGKLALGSVLSENGRG +QLVDWLVANETGDARLRAGLPKDWRIGDKTGTSSTGAVSDIALAWPPGRGPLLVAVYTGE +AKAPVSDLNPVFAEIGKIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8J3I6_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQKI-SYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYKKEDLVDYSPVTEKHVDTGMTIGQIAEAAVRYSDNTAGNILFHQIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Stella humosa TaxID=94 RepID=A0A3N1L1Y6_9PROT +--ATQARLIELEARHGGRLGVSVLDTGSGQRT-EHRANERFAMCSTFKLLAAAMVLERVD +RNEERLDRRILFGSSDVVDYSPATGPRAGGEMTMGEVCEAAMTLSDNTAGNLMLNSFGGP +AAVTTYARGLGDTVTRLDRMETALNEAATGDPRDTTSPAAMVDNLARLTLGPALSEPSRA +QLITWMVANRTGDRRLRAGFPDGWRVGDKTGTGGNGTAADIGVVWRPDRSPLVIAVYCAE +VTASAERRNALFEQVARVI---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. WSM2232 TaxID=944436 RepID=UPI0003FB9919 +--AIRARLTEIEAQSGGRLGVSIIDTTSGLHA-GLRADERFPMCSTFKLLAAGAVLARVD +RGEENLQRRIVYSQSELVPNSPATSRHTRERMSIAELCKAAITLSDNTAANLLLQTFGGP +AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELVMGEQLTSASRV +QLLAWLAANETGGARIRARLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVAVYLTG +TAGNAARSNAAIADVGALVVE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B4455E3 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNKAPIILAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKG5_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKG7_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSHIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B51831 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP +KGYENALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKELTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWGVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVVNAf +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. trifolii TaxID=386 RepID=A0A3E1BR83_RHILT +--NIEKRLAALEKRTGGRLGVSVLDTQTSISF-GYRGDEAFPMCSTFKAPAAGFALARAD +KGDESLDRRVTYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +KLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I2V5_KLEPN +-----EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=6 Tax=Enterobacteriaceae TaxID=543 RepID=Q46759_ECOLX +-----EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Paenibacillus dendritiformis TaxID=130049 RepID=H3SDM0_9BACL +--AAHREFAQLEKKFDARLGVYAIDTGTNQTV-AYRPNERFAYASTYKALAAGALLQQNS +--NDQLDEVITYTKDDLVEYSPVTEKHVAAGMTLGEIAEAAVRYSDNTAGNLLFKELDGP +KGFEKALRQIGDRVTQADRFETELNEAIPGDIRDTSTAKALATDLKAFTVGNALPADKRK +ILTDWMRGNATGDKLIRGGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNSAPIIIAILSSR +DKKDATYNNELIAQAAKVTMNAf +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella sp. BIGb0149 TaxID=2485116 RepID=UPI0010607399 +hdATVNQVKAAERQLKARVGYAELDLASGRLLaSYRPGERFPMMSTFKVPLCAAVLARVD +AGEEKLDRRVRYRQQDLVDYSPVTEKHLADGMTVAGLCAAAITLSDNTAANLLLASVGGP +KGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLTGSVLSAASRQ +QLRSWMVDDKVAGPLLRSTLPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMKERNRQIAGIGETLVKHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus paranthracis TaxID=2026186 RepID=A0A1J9YMX5_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00069477F9 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia kirstenboschensis TaxID=1245436 RepID=UPI000A88DFF2 +---IRARLQEIEADSGGRLGVSIVDTASGLHA-GLHADERFPMCSTFKLLVAGAILARVD +RGEEDLQRRIVYSQSELVSNSPATSKHTRERMSVADLCKAAITLSDNTAANLLLASFGGP +AALTAFARSLGDGITRLDRNEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA +QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIVWPPGRGPILVAVYLTG +TAGDAARCNATIADVGALVAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter gillenii TaxID=67828 RepID=A0A3E2KSF3_9ENTR +-pTTLNKVKEAESQLTARVGYAELDLTSGEILeSYRLQERFPMMSTFKVLLCGAVLARVD +AGKERLDRRIPFSQRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGP +QGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILTTTSQQ +QLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYITE +SQATMEERNRQIAGIGATLIQHw +>[subseq from] Beta-lactamase n=1 Tax=Roseiarcus fermentans TaxID=1473586 RepID=A0A366FRM0_9RHIZ +--AAADRLAALERSAGGRLGVAVLDTSSGETL-LRRADERFPMCSTFKLIAAAAVLKRVD +AGQETLTRFVPYRQADLLGYAPVTKAQVDAGMTLADLCAAAIDWSDNTAANLILDAIGGP +AGFTAFARLLGDSVTRLDRNEPTLNTAIPGDPRDTTTPLAMARDLQAVLLGDVLSEESRR +RLEAWLIADRVGDKRLRAGLPPDWGIGDKTGSGDHGTANTIAILRPPNRAPLLAAVYYTE +GPDSMDARNAVNRQVGEIVAATf +>[subseq from] class A beta-lactamase n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=UPI00034A6AC3 +--EAQAALKALDEGFDGRLGVFALDTGSGATL-GQRAGERFPMCSSFKAVLAASMLDRSR +RQPDWLSHRVRYAKADLVSYSPVTERHVGEGMTVAELCAATVQYSDNGAANLLMAQSGGP +QALTAFARSHGDDSFRLDRIEPALNSAIPGDERDTTTPEAMARLLQRLVVAEGLPPRERQ +QLADWLRGNTTGARRIRAGVPAAWTVGDKTGTGAHGSASDIGVVWRPGMAPLALAIYTTR +PKADAPADEAVIAEAARIVA--- +>[subseq from] Beta-lactamase n=7 Tax=Bacteria TaxID=2 RepID=A0ZX80_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKYLADGMTVGELCAAAITMSDNSAANLLLATVGGP +VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=UPI000F70A6F3 +heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD +TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ +QLQRWMVEDKVAGSLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA +TPASMDERNKQIAAIGETLVRHw +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium crusticola TaxID=1697972 RepID=UPI000FFCA952 +--DAAARLAQLERRDGGRLGVEVRDTGTGRRF-GHRADERFPLCSTFKALAAAAILARVD +RAEESLERRMTYAQADLDAYAPVTGRHVADGMTLADICAAAVVWSDNTAGNLMLRALGGP +EGVTAFARAHGDTLTRLDRTEPTLNTAIPGDPRDTTTPAAMLGLLEAVLLGEALSPASRA +RLAGWMTESPTGAKRLRAGVPADWQVADKTGTGENGTANVVALVRRPGGAPLLASVYLTG +SPAEPDARNALHAEVGRLIARTf +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F86945F +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTLLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. OV084 TaxID=1882777 RepID=UPI0008BDC7FB +--SAEAQLAALESASGGRLGVVGFHTGSGARI-QHRPHERFPLCSTFKLMLAAAVLERST +KDSGLLSRNISYSKADLVAYSPITEKHIATGMTVAAMCAATVQYSDNAAANLLLKVLGGP +PAVTAFARGIGDQAFRLDRTEPELNTSIPGDPRDTTTPAAMADSVQRLALGDALGTVQRD +QLQTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF +PQKDAKGRNDVIASATRIAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pasteurii TaxID=2587529 RepID=A0A5P1KAW6_9ENTR +-dTLQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP +EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ +LQQDAKSRKEVLAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=A0A209A3W8_YERIN +--SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLVAAVLGHSQ +SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL +EMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRE +QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVVYFTQ +LKKAAEPRRDVLAAATKIVLAH- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus pseudomycoides TaxID=64104 RepID=UPI000BEDB623 +--TVNHSFTKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGVLLQKKS +--IEDLDERIVYTSEDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRAIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRE +LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVID-- +>[subseq from] Beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0000470FDC +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMGDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium grahamii CCGE 502 TaxID=990285 RepID=S3I2C2_9RHIZ +-dEINRRMEALEKEIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQETLERRIVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP +AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD +RLAAWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVLWPPGHGAILVAAYVTQ +AKAPVSEINPVFAEVGKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. SCN 67-85 TaxID=1660152 RepID=A0A1E4IVX1_9BURK +--SAEAQLAELERACGGRLGVVAFNTASGARL-QHRPHERFPFCSTFKLMLSAAVLERSA +KDASLLSRRVVYSRADIIPNSPVTEKHVADGMTVAALCAAAIQYSDNAAANLLMKVLGGP +ADVTAFARTIGDQAFRLDRWETELNTAIPGDLRDTTTPAAMADSVQRLVLGDALGAAQRS +QLQTWLLGNTTSAERFMAAVPPGWKVGDKTGGGSYGTNNDVGVMWPPAGAPLVVSVYLTF +PDKDAKTRNDVVASAARIAVS-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B1L4A9_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000978902F +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010300F17 +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAVLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2Z4G2W9_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AC298C +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00027FCE6F +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMCTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. viciae TaxID=387 RepID=A0A4R0CBX1_RHILV +--NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAILDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNSVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=Q2YHY7_KLEPN +-----EQITLSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVMIYLRD +TPATMAERNQQIAKIGAALIEHw +>[subseq from] Beta-lactamase n=7 Tax=Bacteria TaxID=2 RepID=A0A127SJH6_9BACT +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium laguerreae TaxID=1076926 RepID=A0A6B2GWP2_9RHIZ +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARTD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000D74461B +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RP93_9BACT +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. 42MFCr.1 TaxID=1048680 RepID=UPI0003637824 +-dEINRRMDALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP +AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD +KLVAWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYLTQ +AKAPVSEINPVFAEVGKIVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Kluyvera intermedia TaxID=61648 RepID=A0A1X0XGT3_KLUIN +hpATQESAKQAEDQLNARVGYAELDLASGQMRgSYRPQERFPMMSTFKVLLCGAVLARVD +AGQEQLARRIQYRQQDLVEYSPVTEKHPTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP +SELTAFLRKTGDRVTRLDRWETALNEALPDDERDTTTPEAMAQTLRQLLTGKILTPASQQ +QLMAWMEADKVGGPLIRSVIPTGWFIADKTGAGGRGSRGIVAALGPDGKPTRIVVIYLTG +TKATMDERNKKIADIGDSLIKHw +>[subseq from] UPI0011C34229 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0011C34229 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000D74085C +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-45 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A515L5V3_ENTCL +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDKPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / KCTC 32145 / OM5) TaxID=504832 RepID=B6JGD8_OLICO +-qDFEAKIRLIEGKVKGRLGVTALDTGSQRRF-EYRADERFAMCSTFKLLAAAAILKRVD +EGQEQLARRVRYTASDLVTYSPVTEKHIADGMTLAELCEAAITLSDNTAGNLMLAAIGGP +AGLTAYARTLGDSLTRLDRIETALNEAAPGDARDTTVPAAMAADIRKLLFGDALASASKD +QLKTWLLANKTGDMRLRARLPAGWRVGDKTGSGERGTTNDVGFLLRPAASPIIVAAYLTE +TAAPMSARNEALAAVGEAVAAAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhodospirillales bacterium URHD0088 TaxID=1380394 RepID=UPI0012DDC9A7 +----AERLAGLEAGGGGRLGVAILDTADGTYL-GRRADQRFALCSTFKLLAAAAVLQRVD +DGAERLDRRIAFTAQDLDAYAPVTKKHVGPGMTLVELCAAAVEWSDNTAANLLLQTIGGP +AGLTGYARTLGDTVTRLDRTEPALNSAIPGDERDTTSPAAMLQDLRRLLVEDALSPASRQ +RLEGWMRQTKTGTKRLRAGLPAGWRVGDKTGTGENGTTNDVAILRPKGRAALLAAVYLTE +MPGPAARRDAVHAAIGRLVAETf +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. Root411 TaxID=1736530 RepID=A0A0Q7C1W3_9BURK +--SAEAQLAELERASGGRLGVAGFHTGSAARI-QHRAHERFPLCSTFKLMLAAAVLEHSA +KDASLLARRIGYGKADLVSWSPITEKHMADGMTVAELCAATVQYSDNGAANLLLKMLGGP +ATVTAFARGIGDQAFRLDRTEPELNTAIPGDLRDTTTPAAMSDSVQRLALGDALGTAQRE +QLKDWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPLVLSVYLTF +PQKDAKGRSDVIASATRIVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas brassicacearum TaxID=930166 RepID=A0A423H5I1_9PSED +--ELYKQLAELESSAKGRLGVALINTANGHDI-QYRGGERFPFCSTFKLMLAAAVLHKSM +AEPGVLDKHIAYGEADLLSYAPIAKQNLKQGMSVAQLCAATLQYSDNTAANLLIKELGGV +AAVNQFAKSLGDPAFRLDRKEPELNTAIPDDPRDTTTPAAMAASVQKVVLGDALATAQRE +QLAIWLKGNTTGDASIRAGTPTGWVVGDKTGSGDYGTTNDVAVLWPQTGAPVVLAVYFTQ +LQKDAEARRDVLASATRLVMAH- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q7X4G3_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGL +AGLTAFLRQIGDNVTRLDRWETELNEALPADARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=I7B447_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGERCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEF3A18 +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas halocynthiae TaxID=176290 RepID=UPI0004217BE3 +-nELINSVRQIEANLNARVGIAVYDLESKRNW-QYHADDRFPLSSTFKTLACAALLQQAD +TGQQQLAQTVTFTESELVSYSPVTEAFVGTEMTLSALCEATLSMSDNSAANFILDAIGGP +QAVTQFARSIGDNVTRLDRWETELNEAIPGDERDTTTPNAMAMNLEKLVLGEALSPASRQ +QLKHWLTNNQVGDALFRASVPDDWTVADRTGAGGYGSRSIAALLWPPQRKPVVATLYITE +TEASFEDRNAAIAEIGAAIVT-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1V2HAU8_BACCE +-qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-56 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6C0VU04_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=2 Tax=Acidovorax cattleyae TaxID=80868 RepID=A0A1H0SY22_9BURK +--ALARAVQEIEASVGGRLGVALLDMATGRQG-AHRGDERFPLCSTFKLVLAAHVLRRVD +QGQERLDRRITYRKSDLMEYSPETERHVDGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP +LALTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTRGEALSAAARA +RMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDAGLFWPPDRGAVMVSCYLTG +SPAPAEQRDAAIARVGALAA--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola subsp. tropicalensis TaxID=2489014 RepID=A0A455LP07_KLEVA +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITMSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGNAERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-38 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3G3C0M5_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Carbapenemase n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A075X1C7_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase KPC-3 n=25 Tax=Gammaproteobacteria TaxID=1236 RepID=B9VVU9_ECOLX +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. M47T1 TaxID=1179778 RepID=I4N6C4_9PSED +-------FQALESNLGGRLGVWALDTATGATL-GYREEERFAFCSTFKVMLAGAILHRNE +QQPGLLQQRIAYRQGQLVSYSPVTERHVATGMTVAQLCAAGLQYSDNTAANLLLGVVGGT +AVLTAFARSLNDPAFRLDRYETALNSALPGDVRDTTTPRAMASSLQHLALGDGLAAPSRA +QLQQWLRGNTTGEARIRAGVPSGWAVGDKTGSGDYGVANDVAVIWPAARAPWVLAVYTRA +TARNAQPRSEVIAEATRLVVKAw +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola pv. arracaciae TaxID=487851 RepID=A0A2S6ZP74_9XANT +---LRAQWAEIERRTGGRLGISLLDTGTGRRI-GQREDERFPLCSTFKFVLAAAVLQQVD +QGKLALAQRVTIRAADMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLLPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGIDTRNDIAIVWPPGRAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00036B8E49 +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARTD +KGEENLDRRVSYGKDRLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Phytobacter ursingii TaxID=1972431 RepID=A0A0G3QHV2_9GAMM +hpATQESVKQAEDQLNARVGYAELDLTNGQMRgSYRPQERFPMMSTFKVLLCGAVLARVD +AGQEQLARRIQYRQQDLVEYSPVTEKHLTDGMTMAELCSAAITMSDNTAGNLLLSAIGGP +SELTAFLRKTGDRVTRLDRWETALNEALPGDERDTTTPEAMAQTLRQLLTGKILTPASQQ +QLMAWMEADKVGGPLIRSVIPTGWFIADKTGAGGRGSRGIVAALGPDGKPTRIVVIYLTG +TKATMDERNKKIADIGDSLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Enterobacterales bacterium CwR94 TaxID=2025587 RepID=A0A2I0G0U2_9GAMM +--TTVDKVKQVEHQLNPRVGYAEIDLSSGQLLqSYRAHERFPMMSTFKVLLCGAVLARVD +AGKEQLGRRIHYRQQDLITYSPVTEKHLDRGMTVAELCDATITLSDNTAANLLLTALGGP +QALTTFLRSTGDGITRLDRWEPELNDALPGDPRDTTTPAAMAQTLRQLLTGNSLSEASKQ +QLLRWMEEDKVAGPLLRSVLPKGWFIADKTGAGERGSRGIIAALGPDGKPSRIVVIYLTG +SSANMDERNQKIAEIGDALIKNw +>[subseq from] Beta-lactamase class A n=2 Tax=Paenibacillus TaxID=44249 RepID=A0A1G7MSA9_9BACL +-nQVHQQFVQLEKKYDARLGVYAIDTGTNQSI-TYRSNERFAHASTFKALAAGVLLQQNS +--IKQLDKVITYTKDDLVEYSPVTEKHVDTGMKLGELAEAAVRFSDNTAGNLILKELDGP +KGFEKALRQIGDQVTHADRFETELNEAAPGDIRDTSTPQALADDLKALTVGNALPPDKRK +LLTDWMRGNATGDKLIRAGVPKDWEVADKSGAGGYGTRNDIAIIWPPNRAPIIIAVLSSR +DKKDAAYHNELIAEAAKVTMK-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia glumae TaxID=337 RepID=UPI000F5E171F +--AARRQLAALDASFGGRIGVAALDSGSGARL-LHRADERFAFCSTFKTVLVAAVLTRAA +GDPRLLSSVIRYRRQDLVRYSPVSERHVETGMSVAGLCAAALQYSDNSAANLLIRMLGGP +AAVTAYARSIGDRWFRLDRLETDLNDAVPGDERDTTTPAAMLETLRRVTLGDALDAAGRA +RLVGWMLGNTTGDARIRAGVPAGWRVADKTGSGDYGSANDVAVIYPPRRAPIVLAVYTTR +DRKGAGYDNAAIASAARIVTAAf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SJS TaxID=1423321 RepID=A0A176J6D6_9BACI +---TGQKFMQLEKKFDARLGVYAIDTSTNHTV-VYRPDERFAYASTFKALAAGVLLKQNS +--IDKLDEVITYTKDDLVTYSPITEQHVDTGMTLREISDAAIRYSDNTAANLLLQELGGP +NGFEKGLRGIGDKVTEADRFETDLNSAIPGDIRDTSTARALATSLKAFTVDDVLPNDKRT +ILTDWMRRNTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPDRDPIIIAILSTR +DTKDATYNNELIAKAAKVALNSf +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI00062C9472 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=UPI0013F617AB +hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGSVLSSASQQ +QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG +APATMDERNKQIAAIGATLVTHw +>[subseq from] Beta-lactamase n=1 Tax=Variovorax paradoxus (strain EPS) TaxID=595537 RepID=E6UY86_VARPE +---AFAQLAALERASGGRLGVVGFNTATGARV-QHRADERFPLCSTFKLVLAAAVLGRSA +KENGFLARRVNYTKGDLVTYSPITEKNVATGMTVAELCAATVQYSDNGAANLLMKMLGGP +AAVTTFARSAGDDVFSLERWETELNTAIPGDLRDTTTPAAMAASVERLVLGNALGAAQRE +QLKTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGTTNDVGVLWPPAGAPLVLAVYLTF +PDKDAKGRNDVVASATRIAV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia caribensis TaxID=75105 RepID=A0A2T3YB89_9BURK +--DLARQLARIEAQAGGRLGVAILDTASSKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD +QGKEQLGRKIVYAKEVVVANSPVSGPRAGGDMTVGELCEAAITRSDNTAANLLLDSIGGP +AALTAFARSIGDRVTRLDRNEPSLNEATQNDPRDTTTPAAMLADLRALLLGEHLSSASRE +QLTAWLAANKTGDTRLRAGLPKAWRVGDKTGTGERGTSNDIAVVWPEGRAPVLVVAYLTG +ATATATQRDAAIAQVGALVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1T2Q3L5_BACCE +-qATHKEFSQLEKKYDARLGVYAFDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIIN-- +>[subseq from] Beta-lactamase n=1 Tax=Haemophilus parainfluenzae TaxID=729 RepID=G9BBW8_HAEPA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMISTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRLEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDELNRQIAEIGASLIKHw +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F2B0519 +-----EQITLSESQLAGRVGYVEMDLASDRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIAKIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Chelativorans sp. J32 TaxID=935840 RepID=UPI000484C232 +-qAVSDRLALLEKRSGGRLGVAILDVRTGLMA-THRADERFAMCSTFKAIAAAAVLARVD +AGRDDLERRITYGKDKLIVWSPVTEKHAGGRMTLGALCDAAVTMSDNTAGNLLLESLGGP +EGLTAFFRSLGDDVSRLDRWEPDLNNVPPGDPRDTTTPAAMLRSLQKVVLGDALSQTSRQ +RLADWLIANQTGDARLRAGFPDGWRIGDKTGTGTT-VASDIAVAWTPEGATLLISAYLEA +PELSASDRDKIFKEIGEIAAE-- +>[subseq from] SHV/LEN/OKP family class A beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=UPI000F054AE7 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAAL---- +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5YK09_9BACT +--DAATRIAAVEARIGGRIGVAALDTGNTKHV-EHRADERFPMCSTFKFLAAAAVMKRVD +EKKEKLERFVPYGAKEILEYAPVTKEHLKDGMTLGALCAAAIEQSDNTAGNLLLDAIGGP +SGLTNFVRSLGDRVTRLDRIEPELNSAIPGDERDTTTPAAICSDIQRLLLGDALSEASRR +QLEDWLQRNETGGPMIRAGVPKNWILGDKTGRGSNGATNDIAIMRPPDRAPILLAIYSVG +STATPTDRAAAVAEVAKIVAESf +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=UPI0010AE3B0F +hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSTSQQ +QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG +TPATMDERNKQIAAIGATLIRHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000CCC5002 +-qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium mongolense USDA 1844 TaxID=1079460 RepID=A0A559SQW3_9RHIZ +-dDIERRLAELEKRTGGRLGISVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD +KGDENLERRVIYSQDKLVSYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLLLESVAGP +KALTKWLRSIGDRATRLDRWETALNEGKKGDPRDTTTPDAMLDTLGNLALGSVLSEPSRE +KLIEWMLANTTGDARLRAGLPGAWKVGDKTGTGDNGSAADIAIIWPKGRGPILVTAYIAE +ATAPVKELNPVFAEVAKIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI0009BA2A92 +-dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGKEGLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +DGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRQ +QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE +AKAPLDDLTPVFADIGRTAAD-- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. CF316 TaxID=1144317 RepID=J1EJC0_9BURK +---WLAELQRIEASVGGRVGVAALDTHTGRQI-AHRGGERFPMASTFKLLLAAQTLRRVD +QGHDKLDRRITYARKDLVTHSPVTEPHADGALTVEELCAGTMTLSDNTAANLLLASNGGP +PALTAYVRSLGDSITRLDRNEPSLNEARPGDPRDTTTPVAMVHCIQALALGQALSPASRD +KLQGWLLANKTGDKRLRARLPEGWKAGEKTGTASRGTSNDAGVFWPPERKPIVVSCYLTG +GEAPPEQRDAAMAEIGALVAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A485TCF8_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDKVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1G4KXH0_BACCE +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTI-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN +LLIDWMKRNTTGDNLIRAGVPGGWKVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKSDDKLIAEATKIVLD-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0009F08B86 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELXAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAXXRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Verrucomicrobium sp. BvORR106 TaxID=1403819 RepID=UPI00056DD302 +-----SKLEGIEGPDGARLGVYALDIESGMEV-KHRSEERFPVCSTFKMILTSAILKQSV +QDAGLMTRRISYAKEELVTYSPVTEKHVKDGMTVEALCAAAMQYSDNTAANLLMKILGGP +GAVTAFARSIGDSQFRLDRWETELNTALPGDPRDTSSPAAMGHSLRKLALGDGLPETQRA +KLVEWLQGNTTGDKRIRVAVPPDWKVGDKTGSGDYGTANDVAILWPPGRKPIVLAIYHTQ +KAADAKWQNEVIAAAARVVLEAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=R4RZE1_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASTAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALI--- +>[subseq from] Class A beta-lactamase Bla1 n=1 Tax=Bacillus mobilis TaxID=2026190 RepID=A0A6B3KL77_9BACI +---TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQKNS +--TEKLNEVVTYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTKSDRLETELNEAIPGDKRDTSTAKAIATNLKDFTVGNALPDQKRN +ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=A0A3P8IYB9_RAOTE +heATVNQVKTAERQLEARVGYAELDLASGRLLaSYRPGERFPMMSTFKVPLCAAVLARVD +AGEEQLDRRVRYRQQDLVEYSPVTEKHLADGMTVAGLCAAAITLSDNTAANLLLASVGGP +QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLTGSVLSAASRQ +QLRSWMVDDKVAAPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMEERNRQIAGIGETLIKHw +>[subseq from] Beta-lactamase KPC-12 n=2 Tax=Enterobacteriaceae TaxID=543 RepID=F2XNH2_ECOLX +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELEMNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001012F88F +------------RQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus dauci TaxID=1567106 RepID=UPI00061905CE +--SLASSFRMLEQQHQARLGVYAIDTGTGKVV-AYRHNERFAFASTYKALAAAAVLQQNS +--IADLDRVITYSAKDLVEYSPVTEKHVDTGMTLREICEAAIQYSDNTAGNILFQELNGP +AGFQQALRQLEDRTTRSERIEPELNAAVPGDPRDTSTPRALARDLRLFTTGKVLSQDKRQ +LLAEWMKGNTTGDDLIRAAAPKGWIVGDKTGSASYGTRNDIAVVWPPGRSPIIITVLTSH +TDKNAKVDNELVAKATKMVFD-- +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillus dendritiformis TaxID=130049 RepID=A0A4R5YUD2_9BACL +--AAHREFAQLEKKFDARLGVYAIDTGTNQTV-AYRPNERFAYASTYKALAAGALLQQNS +--IDQLDEVITYTKDDLVEYSPVTEKHVAAGMTLGEIAEAAVRYSDNTAGNLLFKELDGP +KGFEKALRQIGDRVTQADRVETELNEAIPGDIRDTSTAKALATDLKAFTVGNALPADKRK +ILTDWMRGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAVVWPPNSAPIIIAILSSR +DKKDAAYNNELIAQAAKVTMNAf +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00099535D2 +-qATHKEFSQLEKKYDARLGVYAFDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIIN-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-43 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A482GPY8_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLRKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella sp. Lac2 TaxID=2594423 RepID=A0A6B0KUS1_9ENTR +heATVATVKHAESQLQGRVGYAELDLASGQLLaGYRPDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTAGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTAFLRHSGDQTSRLDRWETELNEARPGDVRDTTTAQAMARTLRNLLTGRVLSPASQQ +QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAGRIVVIYLTG +TPASMDERNKQIAAIGKTLVAHw +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=UPI0010343F80 +heATVATVKHAESQLQGRVGYAELDLASGQLLaGYRPDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTAGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTAFLRHSGDQTSRLDRWETELNEARPGDVRDTTTAQAMARTLRNLLTGRVLSPASQQ +QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAGRIVVIYLTG +TPASMDERNKQIAAIGKTLVAHw +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderiaceae TaxID=119060 RepID=UPI0009F1A6D1 +---IRQRLKDIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKLLAAAAVLARTD +RGQEDLQRRIVFSQRDLVSYSPATSQHIRERMSVAQLCKAAITLSDNTAANLLLASMGGP +AGLTAFARSLGDGITRLDRNEPTLNEAIPGDPRDTTTPNAMLGNLRELVLGERLSSSSKA +QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDRGTANDVAILWPPGRGPVLVAVYLTE +TSGNAARCNAAIANVGALVVA-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF8826B +-qATHKEFSQLEKKFDARLGVYAIDTGTNQKI-SYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYKKEDLVDYSPVTEKHVDTGMTIGQIAEAAVRYSDNTAGNILFHQIGGP +KGYENALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAEKRE +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013D83189 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSDAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=Q5GJ47_RAOOR +heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD +TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTIGGP +QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ +QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA +TPASMDERNKQIAAIGETLVRHw +>[subseq from] Beta-lactamase n=1 Tax=Massilia lurida TaxID=1036180 RepID=A0A562RKS1_9BURK +------DFAAIERDLGGRLGVAAIDLATGRIA-GNRQDERFPMASTFKATLAAAMLARDA +REPGFIDKRLRYTKADLLSYAPVTSKHVEDGMTVAELCAATVQLSDNTAANVLLKELGGP +QAVTAFARSIGDTTFRLDRWEPELNAALAGDARDTTTPLAMARTLQKLLVGDGLPAPQRR +QLNDWMIGTTTGDKRIRAAAPAGWQVGDKTGTGGYGSTNDIGIAYPPGRGPVVIAIYTHQ +PAKDAPVREDIVAAAARAAF--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia hayleyella TaxID=2152889 RepID=UPI0012912B05 +---AHASLAELERASNGRLGVFALATAGPTLL-SYRADERFPLCSTFKVMLIGAVLARSR +QTEGLLTQHILYGAGDLVAYSPITQPHAGNGMNVAALCAAALQYSDNTAANLLLNIVGGP +AAVTAFARAIGDDTFRLDRIEPELNTAVPGDPRDTSSPAAMARSLQRLVLGDVLGAPQRQ +QLNDWMRGNTTGHARIRAGVPAAWPVADKTGTGDYGTTNDIAVLWPTGLPPVVLAIYFTQ +HKQDAKMRDDMLAAVAQVLAATf +>[subseq from] Class A beta-lactamase LEN-27 n=1 Tax=Enterobacteriaceae bacterium 8376wD9 TaxID=2684233 RepID=A0A6B0EQV0_9ENTR +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8BT24_9BACT +--ELDRRFGQLEKTVGGRLGVATLDTGSGAGS-DHRAGERFPMCSTFKLLAVAGVLARVD +RGRERLDRRIAFSTADLLEYAPVTRARVAEGMPIADLCEAAITVSDNTAANLLLATLGGP +AGLTAYARSLGDNVTRLDRIEPALNEAVPGDPRDTTTPAAMLGDLKALLVGTALARASRE +RLIAWLVATKTGDRRLRAGVPAGWRVGDKTGSGEHGTTNDIGIVWPPGGGAVLVAAYLTE +TSRDTPACEAVLAGVGRMLA--- +>[subseq from] Beta-lactamase n=3 Tax=Enterobacterales TaxID=91347 RepID=Q64HI6_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=Q5XPR7_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0014420A3F +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSETFPMCSTFKALAAAFVLARAD +KGEENIDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus m1293 TaxID=526973 RepID=C2MKX2_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. TND4EL3 TaxID=1907311 RepID=A0A1N6TLC8_9BURK +--AAQTQLAALEQAAGGRLGVAAWRQGSEQRL-AYRADERFPLASTFKAMLAAAVLARSA +SQPGLLEQQVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTILGGP +QAVTAFARSIGNTVFRLERWETELNSAIPGDVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDSWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPGGAPLLIAVYYTR +EQKNADTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. 679 TaxID=2496119 RepID=A0A3S0AV21_9BURK +--SAEAQLAALESASGGRLGVVGFNTGSGARI-QHRPHERFPLCSTFKLTLAAAVLERST +RDSSLLSRHLNYSKSDLIAYSPITEKHVSTGMTVAAMCAATIQYSDNAAANLLLKELGGP +AAVTAFARGIGDQVFRLDRMEPELNTSIPGDPRDTTTPAAMSDSLQRLVLGDALGAAQRE +QLKTWLLGNTTNTERFLAGVPTGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF +PQKDAKGRNDVVASATRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. R693 TaxID=1764276 RepID=A0A246TY13_9RHIZ +-dEINRRMDALEKAIGGRIGVSAIDTDTNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQETLERRVVYEKDKLVTYSPETEKHVGGEMSLSELCQAAITLSDNTAGNLLLESFGGP +AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTQGSALSEPSRD +KLIEWMVANTTGGARLRAGLPDTWKIGDKTGTANNGSAADIAVIWPPGHGAILVAAYVTQ +AKAPVSEINPVFAEVGKIVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00102FA3F7 +--NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLERRVTYGKDKLVDYSPLSEKHAGSDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKDLNPVFAEVGRMIVE-- +>[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000F524155 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia fungorum TaxID=134537 RepID=A0A3R7HSN8_9BURK +-eAIRQRLAQIEVESGGRLGVSILDTMSGLHA-GLRTDERFPMCSTFKLLAAGLVLTRVD +HGQEDLDRRVVFSNSDLVPYSPATGQHTRERMSVADLCKAALTLSDNTAANLLLASLGGP +AAVTAFARSIGDGVTRLDRNEPTVNEATPGDPRDTTTPGAMLGNLRELLLGERLSSPSRA +QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDIAILWPPGRGPILVTVYLTG +TSGDAARSNAAIANVGALVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=Q4L201_RAOPL +hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ +QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG +TPAAMDERNKQIAAIGATLVTHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus MSX-D12 TaxID=1053222 RepID=J8DBE0_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI00101C1C71 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSASSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Carbapenem-hydrolyzing beta-lactamase KPC n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000A17884D +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase LEN-34 n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI00067205DE +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGIEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas putida TaxID=303 RepID=A0A126S6F1_PSEPU +hdPLRQAMQQLEAASGSIIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHRNE +AEPGLLARRIAYGAEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP +PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLTDGLPAGAQQ +QLQAWLKGNTTGDARIRAGLPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG +TKQDAPWNSETIAAATRIVVEAw +>[subseq from] Beta-lactamase n=1 Tax=Phyllobacterium brassicacearum TaxID=314235 RepID=A0A2P7BX07_9RHIZ +--DLSAAFKSLEEKTGARLGVSAHDTGSDNRI-GYRENERFAMCSTFKFLASAAVLARVD +RKEDKLDRMILVKKSDILPNSPATEKNAGKSMSLAALCEAAITLSDNTAGNLILDSLGGP +KGLTEYARGLGDATFRLDRWETELNEAKPGDPRDTITPVAILKDMQKIVLGDALSKSSRD +QLIEWLLANKTGGKRLRAGLPEDWSVGDKTGTSDSGMANDIAVIWPPDRKPILLAVYLYD +PKGTADSRNTIHKKVAALVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00144219D9 +--NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEATVTVSDNTAGNLLLESFGGP +AALTEWVRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKDLNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q1WBU0_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGR------ +>[subseq from] Beta-lactamase n=1 Tax=Bacillus manliponensis TaxID=574376 RepID=A0A073JWR5_9BACI +---IHQGFVQLERKFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAILQQNS +--IEKLNEVITYTEEDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNILFEELDGP +KGFERTLRQIGDKVTIADRFETELNEAIPGDIRDTSTPKTLATNLKAFTVGSALSADKRK +ILIDWMSGNATGDKLIRAGVPENWEVADKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR +DKKDATYDNELIAQATKVTVN-- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase KPC n=101 Tax=Proteobacteria TaxID=1224 RepID=BLKPC_KLEOX +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-26 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1B2AIG7_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Class A beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A0H4IUK8_ECOLX +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-30 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1S6KJP8_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A482M1W9_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase KPC-24 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0H4TDC5_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Class A carbapenemase KPC-2 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000181D380 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=M4HN29_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDLWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=D3JYW1_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase n=1 Tax=Proteus sp. CA142267 TaxID=2050965 RepID=UPI000D6DDB80 +-nTVEEQLNTLEKYSQGRLGVALINTEDNSQI-IYRGEERFAMASTSKVMAVAAVLKASE +KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLEGP +AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEQDAKYRKDIIAKAAEIVTK-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-20 n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2C9PIR8_ECOLX +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax radicis TaxID=758826 RepID=A0A561BDN3_9BURK +---WLAELKRIEASVGGRVGVAALDTHTGRQI-AHRGSERFPMASTFKLLLAAQTLRRVD +QGHDKLDRRITYARKDLVTHSPVTEPHADGALTVEELCAGTMTLSDNTAANLLLASNGGP +PALTAYVRSLGDSITRLDRNEPSLNEAKPGDPRDTTTPVAMVHCIQALALGQALSPASRE +KLQGWLLANKTGDKRLRARLPEGWKAGEKTGTASRGTSNDAGVFWPPERKPVVVSCYLTG +GEAPPEQRDAAMAEIGALVAQ-- +>[subseq from] Beta-lactamase n=2 Tax=Acidovorax avenae TaxID=80867 RepID=F0Q2B9_ACIAP +--ALARAVQEIEASVGGRLGVALLDMATGRQR-AHRGDERFPLCSTFKLVLAAHVLRRVD +QGQERLDRRITYGKSDLMEYSPATERHVGGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP +LGLTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSSAARA +QMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDIGLFWPPDRGAVMVSCYLTG +SPAPAEQRDAALARVGALAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7HZA9_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtARRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A224A9H5_SHISO +------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERIRQIAEIGA------ +>[subseq from] Beta-lactamase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=A0A163LUA3_9BACI +--DLDETFATIESDYDARVGVYAIDTGSDETI-DYRSEERFAFASTYKALAAALVLKQNT +--MEKLEEVITYTEDDLVSYSPITEKHVDTGMTLAELSEAAVRTSDNTAGNLLFEELGGP +EQFQKFLREIGDDVTQSDRYETALNEFIPGNTRDTSTPAALATSLQGFAVGDLLTDDKRA +RLLDWMKGNATGDTLIRAGAPDGWTVADKSGAGRYGTRNDIAVVWPPDREPIILAIMTRH +DTEDADYDDALIAEVAEVTLK-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus sp. CD3 TaxID=1921565 RepID=A0A5J6RWQ9_9GAMM +-nTIEEQLSTLEKYSQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE +KQAGLLDKNITIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP +SKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWVIGDKTGSGDYGTTNDIAVIWPKNHAPLILVVYFTQ +QEQDAKYRKDIIVKATEIVTKPf +>[subseq from] Beta-lactamase n=2 Tax=Burkholderiaceae TaxID=119060 RepID=A0A561MCE8_9BURK +---IRQRLKDIEAESGGRLGVSIVDTTSGLNA-GLRTDERFPMCSTFKLLAAAAVLARTD +RGQEDLQRRIVFSQRDLVSYSPATSQHIRERMSVAQLCKAAITLSDNTAANLLLASMGGP +AGLTAFARSLGDGITRLDRNEPTLNEAIPGDPRDTTTPNAMLGNLRELVLGERLSSSSKA +QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDRGTANDVAILWPPGRGPVLVAVYLTE +TSGNAARCNAAIANVGALVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=Q4L200_RAOOR +heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD +TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ +QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA +TPASMDERNKQIAAIGETLVRHw +>[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=A0A127T5V1_9BACT +heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD +TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ +QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA +TPASMDERNKQIAAIGETLVRHw +>[subseq from] Beta-lactamase n=1 Tax=Mycetohabitans endofungorum TaxID=417203 RepID=A0A2P5KC24_9BURK +-----EALAVLEARMSGRLGVCAIDTGSGARL-VHRAEERFPFCSTFKAVLAAAVLARSG +DTPDWLSQRVRYGSADVVSYSPISGQHVGAGMRIDEMCAATLQYSDNTAANQLMKVLGGI +DAVTAFARSVGDATFRLDRWEPELNTAIPGDVRDTSTPAAMADTLRAVMLGNVLRPWQQQ +RLQQWMLGNRTGDKRIRAGVTAQWRVADKTGTGEYGTTNDIGVLWPPGRAPIVLSIYFTQ +PQQDAPARDEAIEHATRIVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q6ZY77_KLEPN +-----EQITRSESQLAGRVGYVEMDLVSGRTLaAWRANERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIAEKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPASMAERNQQIARIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia rhizoxinica TaxID=412963 RepID=E5AR55_PARRH +-----EALAALEARMRGRLGVCAIDTGSGAQL-VHRAAERFPFCSTFKAVLAAAVLARSG +DTPDWLSQRVRYGLADVVSYSPISGQHAGDGMRIDEMCAATLQYSDNTAANQLMKVLGGP +DAVTAFARSVGDATFRLDRWEPDLNTAIPGDVRDTSTPAAMANTLRAVMLGDGLRPWQRQ +RLQQWMLDNRTGDKRIRAGVPAQWRVADKTGTGEHGTTNDIGVLWPPGRAPIVLSVYFTQ +PRRDAPACDEAIEQATRIVVD-- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q939H5_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAVITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus paranthracis TaxID=2026186 RepID=UPI0011A9C5B0 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKGAIYDNQLIAEAAEVIVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI000522FD2F +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGNTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTVGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=3 Tax=Gammaproteobacteria TaxID=1236 RepID=B6D1Z4_ACIBA +-----EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAAKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=5 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8GMX3_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0007756FE9 +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDILSAEKRN +LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLH-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=A0A379FDS5_PROVU +--TIEEQLSTLEKNSQGRLGVALINTKDNSQI-TYRGDERFAMASTSKVMAVAAVLKESE +KQAGLLDKHMTIKKTDLVTYSPITEKHLATGMTLAQLSAATLQYSDNTAMNKILDYLGGP +SKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPLAMATSLQLLTLGDALGQYQRQ +QLITWLKGNTTGDQSIKAGLPNNWVVGDKTGSGDYGTTNDIAIIWPENQAPLILVVYFTQ +QKQNAKPRKDIIVKATEIVTKEy +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces spinoverrucosus TaxID=284043 RepID=A0A4Y3VL17_9ACTN +------RYAALERRHGARLGVFALATGTGATL-NYRADDRFALCSTFKALAAAAVLHEHP +--LSHLNQRVTYTRAELQSYSPISEDHIETGMTVRELCDAAVRYSDNTAGNLLMRDVGGP +AGLTAYLRGLGDKVSRMDHYEPELNGMAPGDPRDTTTPRAIATTYRDLVLGDALTPDRRA +LLKDWLVRNTTGAKRIRAGVPKGWTVADKTGTGEYGRANDIGIVWPPHTEPLVLAVMTDR +SGHDTPPREALLAEATRLVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A142FK12_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVARLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEDF5A4 +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVCD-- +>[subseq from] Carbapenemase KPC-2 n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=G8HAR0_PSEAI +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVRWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. YR266 TaxID=1884386 RepID=UPI00089803D1 +--SAEAQLAALESASGGRLGVVGFHTGSGARI-QHRPHERFPLCSTFKLMLAAAVLERGT +KDSGLLSRNISYSKADLVAYSPITEKHVATGMTVAAMCAATVQYSDNAAANLLLKVLGGP +PAVTAFARGIGDQAFRLDRTEPELNTSIPGDPRDTTTPAAMADSVQRLALGDALGTVQRD +QLQTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF +PQKDAKGRNDVIASATRIAVA-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001443A7D9 +-qATHKEFSQLEKKFDARLGVYAIDTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=2 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000C7D9149 +-----EQITLSESQLAGRVGYVEMDLASDRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIAKIGAALIEHw +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0012997D37 +-----EQIKLSESQLAGRVGYLEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] GIL family class A beta-lactamase n=1 Tax=Citrobacter freundii TaxID=546 RepID=UPI00129C4EB9 +-pTTLNKVKEAESQLTARVGYAELDLTSGEILeSYRLQERFPMMSTFKVLLCGAVLARVD +AGKERLDRRIPFSRRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGP +QGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILTTTSQQ +QLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYLTE +SQATMEERNRQIAGIGATLIQHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF5A93C +--TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS +LLIDWMKRNTTGDNLIRAGVPRGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010308B20 +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAVLDTLGNLTLGSVLAEASSD +RLVAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus paranthracis TaxID=2026186 RepID=UPI000A0572A8 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0008FE64BA +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIGHw +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella sp. YJ TaxID=1850565 RepID=UPI000A18D793 +hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTSFLHHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ +QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG +TPATMDERNKQIAAIGATLVTHw +>[subseq from] class A beta-lactamase n=1 Tax=Thalassospira sp. MIT1004 TaxID=1882733 RepID=UPI0008DD15F3 +-dRLTDAIHAVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAILHKVD +LGTETLDRRIIYGVEDLVTYSPTTEKHVNGGMTIGELCEATLHLSDNTAANLILDTLGGP +DELTAYLRDIGDDVTRLDRIEPDLNTAKPGDPRDTTTPDAMRASLAYLLLGDALSADSRQ +LLEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPEQKPVIVAIYITQ +TSASMDERNAAIADLGQEIA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium altiplani TaxID=1864509 RepID=A0A109JJA7_9RHIZ +-dEINRRMDALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITPSDNTAGNLLLESFGGP +AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD +KLVAWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYVTQ +AKAPVSEINPVFAEVGKIVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=UPI0004593F0D +--QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAE +RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP +PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQPASRQ +RLADWLLASQTGDTRLRAGLPAGWRIGDKTGVGGHGTNNDIGVIWPRDGAPVLISAYLTQ +SSASREAQNAVLAEVGRIAAH-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacteriaceae bacterium TaxID=1849603 RepID=A0A2Z4N5Z5_9ENTR +--ETLVKVKDAEDKLGARVGYIELDPNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMRTTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRCALPAGWLIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. trifolii WSM2297 TaxID=754762 RepID=J0VYI5_RHILT +--NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGGEAFPMCSTFKALAAGFVLARVD +KGEEKLDRRVTYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +PALTDWLRSIGDGTTRLDRTEPTLNEAKKDDPRDTTSPDAMLDTLGNLTLGSILTEAACD +RLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATASAKELNPIFAEVGKMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Phyllobacterium sophorae TaxID=1520277 RepID=A0A2P7ATM7_9RHIZ +--DLAAAFKTLEEKTGARLGVSAHDTGRDSRI-EYRENERFAMCSTFKFLASAAVLARVD +QRQEQLDRMILIKKSDLVAYSPVTEKYVGKPMSIEAICEAAVTLSDNTAGNLMLDTLGGP +KGLTKYARSLGDATFRLDRWETELNEAKPSDARDTITPAAILKDMQKTVLGDALSKSSRD +QLVEWLLGNKTGDKRLRAGLPKDWSVGDRTGTSDSGMANDLAVIWPPDRKPILLAVYLYD +PKGTADSRNTIHKKVAALVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. M47T1 TaxID=1179778 RepID=UPI0009DA4111 +-------FQALESNLGGRLGVWALDTATGATL-GYREEERFAFCSTFKVMLAGAILHRNE +QQPGLLQQRIAYRQGQLVSYSPVTERHVATGMTVAQLCAAGLQYSDNTAANLLLGVVGGT +AVLTAFARSLNDPAFRLDRYETALNSALPGDVRDTTTPRAMASSLQHLALGDGLAAPSRA +QLQQWLRGNTTGEARIRAGVPSGWAVGDKTGSGDYGVANDVAVIWPAARAPWVLAVYTRA +TARNAQPRSEVIAEATRLVVKAw +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=UPI0005DB3E8F +--SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLVAAVLGHSQ +SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL +EMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRD +QLALWLKGNTTGAAAIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVVYFTQ +LKKAAEPRRDVLAAATKIVLAH- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=Q0GM99_ENTGA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAKPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADTSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. BK068 TaxID=2512130 RepID=A0A4R1YBI6_9RHIZ +-dEINRRMEALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQETLERRVVYDQDKLVTYSPETEKHVGGEMSLSELCEAAITLSDNTAGNLLLESFGGP +AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDSMVDTLGNLTLGSALSEPSRD +KLVEWMVANTTGGARLRAGLPDAWKIGDKTGTGNNGSAADIAIAWPPGHGAILVAAYVTQ +AKAPASEINPIFAEVGKIVAD-- +>[subseq from] Broad-spectrum beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0000EFE329 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMVSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWATELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Methylobacterium platani TaxID=427683 RepID=A0A179S0S6_9RHIZ +--DATARLAQLERRDGGMLGVEVRDTATGRRF-GHRADERFPLCSTFKAIAAAAVLARVD +KGRDDLNRRISYGRDALLSYAPVTSKHVETGMTLAELCAAAVVWSDNTAANLMLDTLDGP +GGITAFARAHGDTVTRLDRTEPTLNTAIPGDPRDTTSPAAMVGLLDNVLLGQALSAESRA +RLIGWMQESTTGLKRVRAGLPEGWRTGDKTGTGDNGTANVVALIHRPDGAPILAAVYLTG +SPAEPAARDALHAEVGRLIARSf +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-42 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A411KB40_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPAGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus anthracis TaxID=1392 RepID=A0A2B0W9N6_BACAN +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNIIFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIAKNLKDFTVGNALPDHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI00076616EE +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLMQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T6Y6_9BACT +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKYLADGMTVGELCAAAITMSDNSAANLLLATVGGP +IGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter gillenii TaxID=67828 RepID=A4KCT8_9ENTR +-pTTLNKVKEAESQLTARVGYAELDLTSGEILeSYRLQERFPMMSTFKVLLCGAVLARVD +AGKERLDRRIPFSRRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGP +QGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILTTTSQQ +QLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYITE +SQATMAERNRQIAGIGATLIQHw +>[subseq from] class A beta-lactamase n=1 Tax=Neptuniibacter pectenicola TaxID=1806669 RepID=UPI000832DE18 +hrSLIQTVERIAGEIEAQVGFAAYDLESGQRW-EYQADQRFAMSSTFKTLACAALLHRVD +AGQESLDRRVSFSESDLVTYSPITEKHAGGQMSLADLCEAALTMSDNTAANLVLQALGGP +EKVTLFARGLGDDVTRLDRWETELNEAVPGDNRDTTTPNEMVKNLQNLLLGDVLSRKSRD +QLYDWLKRNQVADGLFRAAVPEGWIVADRTGAGGFGSRSITAIFWPPERQPIVVALYLTQ +TEASFSERNKAITEIGEAIV--- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia caledonica TaxID=134536 RepID=UPI00047F5CC4 +--TIRARLREIEADSGGRLGVAIVDTTSGLHA-GLHADERFPMCSTFKLIVAGAILARVD +RGEEDLQRRIVYSQSELVPNSPATSKHTRERMSVADLCKAAITLSDNTAANLLLASFGGP +AALTAFARSLGDGITRLDRIEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA +QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIVWPPGRGPILVAVYLTE +TAGDAARCNAAIASVGALVAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora auratinigra TaxID=261654 RepID=A0A1A8Z4V4_9ACTN +----EHAFRQLEERFDARLGVYAIDTGTGRTV-QYRADERFAYASTFKALAAAEILDETT +--DAELDRVVRYSADDLVTYSPITEQHVAEGMTLRAIADAAVRYSDNTAANLMFRHLGGP +QKIEKELREIGDKVTDPARYETELNEARPGDRRDTSTPRALAHDLRAYAVGNALDPADRD +ILNGWLRGNTTGGELIRAGVPDGWVVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEKDADYDNALIAEATKAALADw +>[subseq from] class A beta-lactamase n=1 Tax=Methylocapsa sp. S129 TaxID=1641869 RepID=UPI00131EB64E +--RANDEIAALEAREGGRLGVAVLDSASGLSL-AHRAEERFPMCSTFKLLAAAAVLSRVD +AGSEQLDRKVPYGAADLLEYAPVTKAHLADGMSVGDLCAAAIDWSDNTAANLLLQIIGGP +AGFTGYARSLGDSVTRLDRNEPTLNTSIPGDERDTTTPLAMARAMQAVLLDKKLSEASRR +QLEAWLMGDKVGDKRIRAGLPPSWRIGDKTGSGDNGSTNAIAIIWPPDRAPLLATVYYTG +STASVDARNGVHKDIGAIIAKTf +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI000A0F73B4 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGE--SRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Erwinia sp. ErVv1 TaxID=1603299 RepID=UPI0008335E7A +---IQQKLAVLEKNAGGRLGVALIDTADNSQV-AYRGDERFPLCSTSKVMAVAAVLKKSE +ADDNLLQKRLAIKTSELVNYNPITEKHLNSGMTLGELSAAALQYSDNTAMNKLVGYLGGP +AKVTDYARSLGDALFRLDRTEPTLNTAIPGDARDTTTPVAMADSLRKLTLGHALKAAQRT +QLIEWMKGNTTGSESIRAGLPASWSVGDKTGSGDYGSTNDIAVIWPENRAPVILVTYFTQ +PRQDASSRKDVLAAAARIAV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A649UHP6_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKD9_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYPQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=A0A3S2VHD7_RHIML +--DVTERLRRLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGREVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP +EGLTSWLRSIGDETTRLDRTEPELNEARKGDPRDTTTPAAMLDTLGKLVLGPVLSQEGRQ +QLIDWLVANKTGDARLRAGLPKDWRIGDKTGTSMTGAVSDIAVAWPQGRGPILICVYMGE +AKAPLGDLNPVFADIGSIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A517IA09_BREBE +--AMDQKFAALETKFDARLGVYAIDTETDVVV-AYREDERFAFASTYKALAAGAVLHQKP +--LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADATIRYSDNTAGNLLFKELGGP +KGFESALRQIGDSVTMSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGDVLSSEKQT +ILIEWLQGNTTGDKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIIIAVLSSR +DKQDATYDDALIAEATKVAVD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI0009B5696E +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP +KGYENALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNKAPIILAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Thalassospira xiamenensis TaxID=220697 RepID=A0A367X640_9PROT +-dRLTDAIHAVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAILHKVD +LGTETLDRRIIYGVEDLVTYSPTTEKHVDGGMTIGELCEATLHLSDNTAANLILDALGGP +DELTAYLRDIGDDVTRLDRIEPDLNTAKPGDPRDTTTPDAMRASLAYLLLGDALSADSRQ +LLEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPEQKPVIVAIYITQ +TSASMDERNAAIADLGQEIA--- +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=UPI0013977C6F +heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD +TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ +QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA +TPASMDERNKQIAAIGETLIRHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010318498 +---IDLRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPVKELNPVFAEVGRIIVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=B0FTU2_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASXRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEH- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas frederiksbergensis TaxID=104087 RepID=A0A1J0EFU1_9PSED +--ELYNKLAELESSAKGRLGVALINTANGHEI-QYRGGERFPFCSTFKLMLAAAVLHKSM +AESGLLEKHIAYGEADLLSYAPIAKQNLKQGMSIAQLCAATLQYSDNTAANLLIKVLGGV +AAVNQFAKSLGDPAFRLDRWEPELNTAIPDDLRDTTTPAAMAASVQKVVLGAALATAQRE +QLATWLKGNTTGDASIRAGTPAGWVVGDKTGSGDYGTTNDVAVLWPQTGAPVVLAVYFTQ +HQKDAEARRDVLAAATRLVMSH- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0G3ICX4_KLEPN +-----EQIKLSESQLSGRVGMIEMDLVSGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A4Q8XGV6_RHILE +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALASAFVLARAD +KGEENLDRRVSYGKDTLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPVKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI000D1624BC +--ALARAVQEIEASVGGRLGVALLDMATGRQG-AHRGDERFPLCSTFKLVLAAHVLRRVD +QGQERLDRRITYGKSDLMEYSPATERHVDGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP +LGLTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSAAARA +QMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDIGLFWPPDRGAVMVSCYLTG +SPAPAEQRDAALARVGALAA--- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001368BA11 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTALLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVQPAGWFIADKTGAGERGARGIVALLGPNNKAGRIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia kirstenboschensis TaxID=1245436 RepID=UPI000B01DBD1 +--TIRARLQEIEADSGGRLGVSIVDTASGLHA-GLHADERFPMCSTFKLLVAGAILARVD +RGEEDLQRRIVYSQSELVSNSPATSKHTRERMSVADLCKAAITLSDNTAANLLLASFGGP +AALTAFARSLGDGITRLDRNEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA +QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIVWPPGRGPILVAVYLTG +TAGDAARCNAAIADVGVLVAQ-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKF8_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +RLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Variovorax TaxID=663243 RepID=UPI00089614F9 +--SAEAQLAELERTSGSRLGVVGFNTGSGARV-QHRPHERFPLCSTFKLMLAAAVLERST +KDGSLLSRNLSYGKSDLIDHSPITEKHVATGMTVAAMCAATIQYSDNAAANLLLKELGGP +AAVTAFARGIGDQVFRLDRMEPELNTSIPGDPRDTTTPAAMSDSLQRLVLGDALGAAQRD +QLKTWLLGNTTNTERFLAGVPAGWKVGDKTGAGSYGTTNDVGVLWPPAGAPIVLSVYLTF +PRKDAKGRNDVVASATRIAA--- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A371UQF3_9BACI +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTI-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN +LLLDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKSDDKLIAEATKIVLD-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00132F604E +-----EQIKQSESQLSGRVGMIEMDQASGRTLtAWRADERFPMMSTFKVVLCGAVLARGD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B1IDR9_BACCE +--TVNHSFAKLEKEFDAKLGIYALDTDTNQIV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN +LLIDWMKRNTTGDKLIRAGVPRGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKI6_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPHLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. trifolii (strain WSM2304) TaxID=395492 RepID=B5ZUP0_RHILW +-dNIQKRLAALEKRTGGRLGVSVLDTDTSISF-NYRGSEAFPMCSTFKALAAGLVLARAD +KGEESLDRRVTYGKDKLVDYSPLSEKHADADMTITELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPKLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLSEASSD +RLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGPNGSLGDIAVIWPPNRGPIVAAVYIAE +ATAPVKELNPVFAEVGRMIME-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI001431B246 +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVEIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPARAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI00040EE991 +-dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGTLLLESFGGP +QGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRK +QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE +AKAPLDDLNPVFADIGRIVAD-- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X8T1_9BACT +--SIAKKLSKLETSFDGQIGILAINTANNQRI-QYRADERFPIQSTFKVMAVSAILKQSM +TDKHLLQQKVTYTKQDLVFWSPITEKHLADGMTISELCAAAMMYSDNTATNLIVKKLGGP +SAVTTFARSIGDNTFRIDSWEPELNSN-SSDPRDTSTPTAMEKSLQKLTLGNVLASPQRE +QLVTWMKGNTTGDARIRAGVPKGWIVADKTGAGDYGISNDIGIIWPPSCAPIVVTIYSVH +NNKDTARRDDVIASATRMLIHEf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola subsp. tropicalensis TaxID=2489014 RepID=A0A455LP12_KLEVA +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITMSDNSAGNLLLATVGGP +TGLTAFLRQIGDNVTRLDRWETALNEALPGDMRDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Methylobacterium TaxID=407 RepID=A0A0C6FFB3_9RHIZ +--DAAARLAQLERRDGGRLGVEVRDTATGRRF-GHRADERFPMCSTFKAIAAAAVLARAD +KGQDDLNRRISYGRDDLLSYAPVTSKNVETGMTLAELCAAAVVWSDNTAANLMLATMGGP +AGITAFARAHGDGVTRLDRTEPTLNTAIAGDPRDTTTPAAMVGLLDNVLLGQALSAESRG +KLVGWMHESPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG +SPAEPAARDTLHAEVGRLIARSf +>[subseq from] UPI0011C34287 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0011C34287 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVRWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. YR752 TaxID=1884383 RepID=A0A286AZS7_9BURK +--SAEAQLAALESASGGRLGVVGFHTGSGARI-QHRPHERFPLCSTFKLMLAAAVLERST +KDSGLLSRNISYGKSDLVAYSPITEKHIATGMTVAAMCAATVQYSDNAAANLLLKVLGGP +PAVTAFARGIGDQAFRLDRTEPELNTSIPGDPRDTTTPAAMADSVQRLALGDALGTVQRD +QLQTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF +PQKDAKGRNDVIASATRIAVA-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000A3C72FE +-qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000975E02A +-qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=3 Tax=Klebsiella TaxID=570 RepID=Q2YHX9_KLEPN +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000BFD3909 +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTI-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKSDDKLIAEATKIVLD-- +>[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013D01D65 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQRLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0013BCCA3F +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAVLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas oleivorans TaxID=1735121 RepID=A0A2T5G341_9SPHN +--ALNARIARIEAESGGRLGVFLLDSGSGPRF-GYRARELFPMCSTFKFLLAAMILARVD +RGKERLDRRIRFGPEAIVTYAPITGKHVGGDMSIAELCEATMTLSDNVAANLLLDTIGGP +TALTAWLRTIGDKVTRLDRNEPSLNEARAGDPRDTTTPLAMLGNLRKLLIGRTLSAPSRA +LLTSWMVGNRTGDRRLRAGLPSGWRVGDKTGTGENGTYNDIAIIWPPERPPLLMTAYLTQ +ARPD--RGDATLAEVARAMAE-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas mosselii TaxID=78327 RepID=A0A290HL33_9PSED +hdPLRQAMQQLEAASGSIIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHRNE +AEPGLLARRIAYGAEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP +PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLTDGLPAGAQQ +QLQAWLKGNTTGDARIRAGLPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG +TKQDAPWNSETIAAATRVVVEAw +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. 1180 TaxID=2587049 RepID=UPI00119BED18 +--SAEAQLAELERASGGRLGVAGFNTGSGVRL-QHRAHERFPLCSTFKLMLAAAVLERST +RDGSLLSRNLIYGKGDLIDHSPITEKHVATGMTVAAMCAATIQYSDNAAANLLLKELGGP +ATVTAFARGIGDQTFRLDRTEPELNTSIPGDPRDTTTPSAMSDSIQRLVLGDALGAAQRD +QLKTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF +PQKDAKGRNDVIASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000E0F08A8 +--EIDRRIGELEKRIGGRIGVSAIDTETNVSF-GYRETESFPMCSTFKVLAAGMVLSRVD +KGQENLERRIVYDKDKLVTYSPETEQHVGGEMSVGELCKAAITLSDNTAGNLLLESIGGP +KELTNWLRTLGDGSTRLDRWETDLNEAKKGDRRDTTTPDAMLDTLGNLALGSVLSEPSQN +TLVEWMVANTTGAARLRAGLPESWKIGDKTGTGNNGTAGDIAIAWPPGHGPILIATYVAE +AQVPVSEINPIFAEVGRIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. RP3T TaxID=2135446 RepID=A0A2T3VNW1_9ACTN +----EQAFRQLEERFDARLGVYAVDTGTGRTV-QYRADERFAYASTFKALAAAEVLDGTT +--DAELDRVVRYSADDLVTYSPVTEQHVATGMTLRAIADAAVRYSDNTAGNLMLRHLGGP +QKFEKELRGIGDKVTDPARYETALNEARPGDRRDTSTPRAMAGSLRAYTVGTALEPADRD +TLNGWLRGNTTGGELIRAGVPAGWVVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAILSSR +DQEDADYDNALIAEATKAAVADw +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=UPI00104A2918 +heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD +TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ +QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA +TPASMDERNKQIAAIGATLVRHw +>[subseq from] Class A beta-lactamase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=A0A5Q0MA57_VARPD +---AGAQLAELERACGGRLGVAGFHTGSGVRL-QHRAHERFPLCSTFKLMLAAAVLERST +TDASLLGRRISVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP +AAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPAAMSDSVQRLALGDALGAPQRE +QMREWLLGNTTSTERFLAGVPAGWRVGDKTGAGSYGTTNDVGVLWPPSGAPLVLSVYLTF +PDKDAKGRNDVVASATRIAVK-- +>[subseq from] Beta-lactamase KPC-4 n=5 Tax=Enterobacteriaceae TaxID=543 RepID=B1PL86_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVRWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Enterobacteriaceae bacterium ENNIH2 TaxID=1920109 RepID=A0A2I8QHC4_9ENTR +-----ETVKKAEDQLNARVGYAELSLANGQMLgSYRPQERFPMMSTFKVLLCGAVLSRVD +AGQEQLARRIQYRKQDLVAYSPVTEKHLTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP +SALTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQMLRQLLNGKILTPASQQ +QLMAWMEADKVGGPLIRSVMPAGWFIADKTGAGERGSRGIVAALGPDGKPARIVVIYITE +TQATMDERNKKIADIGASLIKHw +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=UPI0010D25799 +hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ +QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAERIVVIYLTG +TPATMDERNKQIAAIGVTLVTHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDBA01F +-dEINRRMDALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP +AELTKWLRMLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD +KLAAWMEANTTGAARLRAGLPDTWKIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYVTQ +AKAPVSEINPVFAEVGKIVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia unamae TaxID=219649 RepID=UPI000D5F7C7C +--ALENELAAIEAQAGGRLGVAMLDTANGQTR-GWRMHERFPMCSTFKLLLASAVLTRKD +RGKEDLARKVVYTQAQVVSYSPLSGPRAGGEMTVAELCEAALTRSDNTAANLLLESIGGP +PALTAFARGIGDPLTRLDRNETTLNEAIPGDPRDTTTPAAMLADMRALLLGERLSAGSRE +QLIAWLVANKTGDARLRAGLPKDWRVGDKTGTGDRGTANDIAIIWPAGRAPLLVTTYLTG +ATASPAQRDAAIAKVGAWVAK-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D616_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSPRSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae (strain 342) TaxID=507522 RepID=B5XQY6_KLEP3 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSPRSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Class A beta-lactamase n=1 Tax=Proteobacteria bacterium 228 TaxID=2083153 RepID=A0A2S5KL09_9PROT +--GLAEAVRNGERKLQGKIGVSLLDTDTGMGW-SHRGDERFAMCSTFKVLACSAILKQVD +DGRLSLTQRLTFNQQDVVSYSPISKAFAGKPMSLGEICHAAMTYSDNTAANLIISQLGGP +QAVTDFARSIGDGVSRLDRWETALNTAIDNDPRDTTTPEAMTSNLQRLLLGDVLSTASQQ +QLGQWLRDNTTGGSRIRKGIPETWQVGDKTGSGDNGTANDVAILWPPGQKPLLLSIYITQ +AKADWNACSAVIAGISAAIAAEy +>[subseq from] Beta-lactamase n=1 Tax=Serratia rubidaea TaxID=61652 RepID=A0A1L2F514_SERRU +-pATLDTIKDAESRLHGRVGYAELDLVSGKMMdSYRSDERFPMMSTFKVILCGAVLARVD +AGQEQLDRRIRYRQNDLVEYSPVTEKHLAEGMNVGELCHAAITMSDNTAANLLISTLGGP +SGLTAFLRKTGDSVSRLDRWETALNEALPGDERDTTTPESMARTLHNLLTGDALSAESRR +QLMRWMEMDNVAGPLLRSVLPAGWFIADKTGAGERGSRGIVAALGPDGKPSRIVVIYLTG +TKATMDERNKQIADIGAALINHw +>[subseq from] Class A beta-lactamase n=1 Tax=Edaphobacter sp. 12200R-103 TaxID=2703788 RepID=A0A6B9YYE1_9BACT +-eDLAQEFAKIEAGSKGRLGVAVA-LPSGSRM-QHRGEERFPMCSTFKFLAASLVLQRVD +AGREHLDRQVSFSKNDLVTYSPETEKHAGGSMSVAELCKAALTLSDNTAANLLLASFGGP +PAVTGFARSIGDTMTRLDRTETSLNEATPGDPRDTTTPNAMLRNLEKILLGAVLKPSSRK +RLTEWMLANTTGKAKFVAGLPPDWKVADKTGSGEHGSNNDIGVLYPPSGRPVLVASYLTE +TEISNDERNAIHAEIARAIA--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mobilis TaxID=2026190 RepID=UPI000A00B47B +---TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQKNS +--TEKLNEVVTYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTKSDRLETELNEAIPGDNRDTSTAKAIATNLKDFTVGNALPDQKRN +ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKG9_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILkSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYPQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000F8D3824 +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009B52E4F +--ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNKRFAYASTYKALAAGAVLQQNS +--IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP +KGFEKALRQIGDKVTVANRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK +ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR +DKKDATYDNELIAQAAKVTIN-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A097BQY7_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERCARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Acidobacteriaceae bacterium KBS 146 TaxID=639030 RepID=UPI000553155B +-dDLAAALAAAEAKSKGRLGVAIL-FPSGKRM-AHRGDERFPMCSTFKFLAASLVLQRVD +QGKERLDRAVKYSRSDLVEYSPETEKHAGGSMTIAELCKAALTLSDNGAANLLLASFGGP +PAITAFARSLGDTMTRLDRTETTLNEAIPGDPRDTTTPNEMVANLKKIFFGTVLKTDSRK +QLADWMLANTTGKTKFVAGLPADWKVADKTGSGSHGSNNDIGVLYPPTGKPILIASYLTQ +TAISTEERNAIHADVARAVL--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=L7QJB7_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERMSQIVDMGGSLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF9259A +----KHHFVKLEDKFDARLGVFALDTGTNQTV-TYRADERFTYASTSKALAVGALLQQKT +--IEDLNQRITYTQDDLVNYNPITEKHVDTGMTLKELCDAALRYSDNTAMNLILKQIGGP +NGLEKALRDVGDNVTMPEQFEPELNEVKPGETHDTSTPRALATSLQSFTLGDVLPIEKRE +LLIDWMKRNTTGDSLIRAGVPKGWVVADKTGSGSYGTRNDIAIIWPPKGEPIMLAILSSR +DKKDANYNDKLIAEATKEVINAy +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. DB0501 TaxID=2709665 RepID=UPI0013EA3F95 +--DAAARLAQLERRDGGMLGVEVRDTATGRRF-GHRADERFPMCSTFKAVAAAAVLARVD +KGQDDLNRRITYGRNALLSYAPVTGKHVETGMTLAELCAAAVVWSDNTAANLMLDTLGGP +AGITAFARAHGDTVTRLDRTEPTLNTALAGDPRDTTSPAAMVGLLDNVLLGRALSGDSRA +KLVGWMQESPTGLKRVRAGLPDGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG +SPAEPAARDAVHAEIGRLIARSf +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEEDFFD +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase n=1 Tax=Enterobacteriaceae bacterium ENNIH1 TaxID=2066051 RepID=A0A2I8QFX2_9ENTR +-pATLESVKQAEDQLNARVGYAELDLANGQMRgSYRPQERFPMMSTFKVLLCGAILARVD +AGQEQLARRIQYRQQDLVEYSPVTEKHLTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP +SELTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQTLRQLLTGKILTPASQQ +QLMAWMEADKVGGPLIRSVMPTGWFIADKTGAGGRGSRGIVAALGPDGKPTRVIVIYLTG +TQATMDERNKKIADIGASLITHw +>[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000939A028 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGAANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=BLAC_PROVU +-nTIEEQLSTLEKYSQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAILKESE +KQAGLLDKNIIITKSDLVAYSPITEKHLATGMSLAQLSAATLQYSDNTAMNKILDYLGGP +SKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPKNHAPLILVVYFTQ +QEQDAKYRKDIIVKATEIVTKEf +>[subseq from] Beta-lactamase n=1 Tax=Labrenzia aggregata (strain ATCC 25650 / DSM 13394 / JCM 20685 / NBRC 16684 / NCIMB 2208 / IAM 12614) TaxID=384765 RepID=A0NLL2_LABAI +---LEKTVQDAESRLSARIGVAVLDSETGKTF-THRADERFPLNSTFKAFLCAALLEKGE +QGEVQPDRRVKIRKEDLVSYSPVTEKKVGSGMTYLELCDAAITISDNAAANLVLEAVGGP +QGLTDYLRGIGDTITRLDRTEPALNEGQAGDSRDTTTPAAAVATLQKLVLGDALSPSARD +QLTGWLLDNQVGKATLRAGLPEEWPVADKTGAGGNGSRNNIGVIWPDDRQPVVIAVYITQ +TDASFDDRNKAIADIGAALAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=A0A640JJY9_9BURK +--DAETQLAELERACGGRLGVSGFHTGSGARL-QHRAHERFPLCSTFKLVLAAAVLERSA +TDASLLGRRISVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP +AAVTAFARRIGDTTFRLDRTEPELNTSIPGDPRDTTTPAAMSDTVQRLALGDALGAPQRE +QMREWLLGNTTSTERFLAGVPKGWRVGDKTGAGSYGSTNDVGVLWPPSGAPLVLSVYLTF +PDKDAKGRNDVVASATRIAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000FBC16B7 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFAQ-HGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKD5_9BACT +--ETLVKVKGAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus (strain AH187) TaxID=405534 RepID=B7HS58_BACC7 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus swezeyi TaxID=1925020 RepID=A0A1R1QG29_9BACI +------DFAKLEDQFDARLGVFAWDTGTSETI-AYRADERFAYASTHKALAVGALLQKKS +--IADLDKRITYTREDLVNYNPITEKHVDTGMTLKELCDASLRYSDNTAENLILKQLGGP +AGLKKSLREIGDNVTNPERFEPELNEVKPGETHDTSTPRALAESLQTYTIGDALPKEKRS +MLIDWLKRNTTGDTLIRAGVPKGWEVADKTGSGSYGARNDIAVIWPPKGDPIVLAILTSR +DQKDADSNDKLIAQAAKEVIETf +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI000D1632D0 +--ALARAVQEIEASVGGRLGVALLDMATGRQG-AHRGDERFPLCSTFKLVLAAHVLRRVD +QGQERLDRRITYGQSDLMEYSPATERHVDGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP +LGLTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSAAARA +QMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDIGLFWPPDRGAVMVSCYLTG +SPAPAEQRDAALARVGALAA--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX82_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADRTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX81_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADRTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus pseudomycoides TaxID=64104 RepID=UPI000BF62D19 +--TVNHSFTKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS +--IEDLDERIVYTSEDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRAIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRE +LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVID-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0003735CAF +--TVNHSFTKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS +--IEDLDERIVYTSEDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRAIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRE +LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVID-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00103B981E +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFALARAN +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus pseudomycoides TaxID=64104 RepID=C3BTF1_9BACI +--TVNHSFTKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS +--IEDLDERIVYTSEDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRAIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRE +LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVID-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. Root473 TaxID=1736541 RepID=A0A0Q7LRS7_9BURK +---AQAQLAELERACGGRLGVAGFHTRSGARL-QHRAHERFPLCSTFKLMLAAAVLERST +TDASLLGRRISVGKGDLVSHSPVAEKHLATGMTVREMCAATMQYSDNAAANLLLKVLGGP +AVVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPTAMSDSVQRLALGDALGAPQRE +QMCEWLLGNTTSTERFLAGVPAGWRVGDKTGAGSYGTTNDVGVLWPPSGAPLVLSVYLTF +PDKDAKGRNDVVASATRIAVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Undibacterium sp. B2R-29 TaxID=2528175 RepID=UPI00138A0276 +----RQELARLEKSFSGSIGVYLLDPHTRRHF-SYQGEKRFAFCSTFKALLGAAILHKSS +QDGDLLEREITLNSSDFVTYSPVTEKHKDGSMRIADLCAATIQTSDNTAANALLRELGGP +AALTAYMRSIGDNAFRLDRWETELNSALPGDLRDTSTPSAMANSLHKLVLGNALAEPQKH +MLKEWLIGNTTGNTRIRAGLPQGWLVGDKTGTGDYGSAHDIAVVWPPSRAPFVLAIYTCR +KKKDSEARSDIIAEVTRVLVQQw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sp. Sh_2011b TaxID=1076164 RepID=G3ESI3_9ENTR +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRELLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGVIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGA------ +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q1WBU1_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGA------ +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI000DE624C6 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITSSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMDADKVAGPLLLSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI001030FF05 +---IDLRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPVKELNPVFADVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. 9120 TaxID=1500897 RepID=UPI000551541C +--TIRRRLAQIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKVLAAGAVLTRVD +RGQEDLARRVVFSQRDLVPNSPATSRHTRERMSIAELCKAAITLSDNTAANLLLATFGGP +AGLTAFARDLGDGITRLDRIEPMLNEAIPGDPRDTTTPNAMLGNLRELVLGEHLSSSSRA +QLLAWLVANETGGARIRAKLPQEWGVGDKTGTGDHGTANDIAILWPPGRGPVLVAVYLTG +TNGDAARCNAAIAEVGALVVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Thalassospira sp. TaxID=1912094 RepID=A0A2E2T5W8_9PROT +-dRLTDAIHAVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAILHKVD +LGTETLDRRIIYGVEDLVTYSPTTEKHVNGGMTIGELCEATLHLSDNTAANLILDALGGP +DELTAYLRDIGDDVTRLDRIEPDLNTAKPGDPRDTTTPDAMRASLAYLLLGDALSADSRQ +LLEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPEQKPVIVAIYITQ +TSASMDERNAAIADLGQEIA--- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI0009BAB105 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +APASMAERNQHIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00104070FB +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAVLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TPVPVKELNPIFAEVGRMVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. 369 TaxID=1705714 RepID=UPI000F7F0C7E +--SAEAQLAELERASGGRLGVAGFNTGSGVRL-QHRAHERFPLCSTFKLMLAAAVLERST +RDGSLLSRNLSYGKGDLIDHSPITEKHVATGMTVAAMCAATIQYSDNAAANLLLKELGGP +ATVTAFARGIGDQTFRLDRTETELNTSIPGDPRDTTTPSAMSDSIQRLVLGDALGAAQRD +QLKTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF +PQKDAKGRNDVIASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Phytobacter ursingii TaxID=1972431 RepID=UPI001158A877 +hpATQESVKQAEDQLNARVGYAELDLTNGQMRgSYRPQERFPMMSTFKVLLCGVVLARVD +AGQEQLARRIQYRQQDLVEYSPVTEKHLTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP +SELTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQTLRQLLTGKILTPASQQ +QLMAWMEADKVGGPLIRSVIPTGWFIADKTGAGGRGSRGIVAALGPDGKPTRIVVIFLTG +TQATMDERNKKIADIGASLIKHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFA8959 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYKKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +NGYEKALRQLGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAQKSK +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B8HZD4_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYKKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +NGYEKALRQLGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAQKSK +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D3A62B2 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSVANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Rhodospirillales bacterium 69-11 TaxID=1895825 RepID=A0A1Q3UZN6_9PROT +---AEETFAMLEAQSGGRLGVAALDTGSGRQF-GTRATERFPLCSTFKLLLAGSVLARVD +AGQEKLDRIVQFTRAQLVPYSPATGPAADGPMRVGALCEAAVTLSDNTAANLLLGSMGGP +AGLTRFIRSLGDEVTRLDRTEPTLNEAVPGDPRDTTTPADMVRDMQRLVLGDALSRASRG +QLVTWLRANKTGDKRLRAGVPPGWQVGDKTGTGERGTANDAGILWPPGGAPILVAAYLTG +ATRTPAERDATLAGVGRIVAA-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI00057802A2 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEVAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Neorhizobium sp. P12A TaxID=2268027 RepID=UPI0011ED946F +--DADKQLAELEKKTGGRLGVAVLDTETNISL-GYRENERFFMCSTYKALAAGFVLARAD +KGEEKLDRRVMFGKDALVSYSPVTEKHAGTDMTVAELCEAAITMSDNTAGNLLLDSFGGP +SALTAWLRATGDDETRLDRREPDLNEAKKGDLQDTTTPDSMLDTIGLLTLGDTLSEASRN +HLIDWMVADKVGDARLRAGVPKDWKIGDKTGTGNNGALGDIAVIWPPDRGPFIVAVYIAE +ATAPMKDLNDVFAAVGKLV---- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A3S3ZWP3_RHILE +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARGD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Micromonospora TaxID=2617518 RepID=A0A2G6XDN6_9ACTN +--DWDHEFRRLEERFDARLGVYAIDTGTGQTV-QYRADERFAYASTFKALAAAEILDETT +--DAELDRVVRYSADDLVTYSPITEQHVAEGMTMRAIADAAVRYSDNTAANLMLRHLGGP +QKFEKELRKIGDKVTDPARYETELNEGRPGDRRDTSTPQAMAGSLRAYTVGDALEPSDRD +TLNGWLRGNTTGGALIRAGVPDGWVVGDKTGSGGYGTRNDIAVIWPPNRAPIVLAVLSSR +DEKDADYDDALIAEATKVVMASw +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) TaxID=358681 RepID=C0Z7D8_BREBN +---MDIKFAALEKQFGARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP +--LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP +KGFESALRQIGDGVTKSERYETELNEAKPEDTRDTSTPKALATSLRAYTVGNALSSDKQK +ILIEWLQGNTTGAKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR +DKQDATYDDALIAEATKIVVD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Massilia albidiflava TaxID=321983 RepID=A0A411WZK6_9BURK +-------FSDVERDLRGRLGVAVIDTATGKTT-GHRLGERFPMCSTFKAVLAAQALAREA +REPGFLARRLRYAKADLVSHSPITGKHVDTGMTVADLCAATVQYSDNTAANALMKELGGP +AGLTAFMRGLGDTQFRLDRWETELNTAIPGDDRDTTTPWAMARTLEKLVIGDALPAPQRQ +QLKDWLLGNTTGGKRIRAAVPAGWQVGDKTGTGAYGVTNDIGIVYPPGRAPLVVVIFTHL +AEKDGDNRDDIVVAAAR------ +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0U3A6C6_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKQLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLI--- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf106 TaxID=1736255 RepID=UPI000B1B3F02 +-rDLADRFARIEEASGGRLGIGLLDTGSGAHA-AHRGDERFPLCSTFKVLAAGAVLARVD +RGEDGLDRRLRYEPREVVPYSPVSGPRAGGEMTIAELCEAAVTLSDNTAANLLLGTMDGP +AGLTGHIRGFGDSTTRLDRTEPDLNEAAPGDARDTTTPLAMAETLRRLVLADALSPASRA +LLTAWLVGCRTGDARLRAGLPQDWRIGDKTGSGENDTANDVAVIWPPRRPPLVLTVYLTG +ARTSSEARSATIASVARAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. Leaf93 TaxID=1736249 RepID=A0A0Q4XFK2_9RHIZ +--DLAGRFASIEEASGGRLGIGLLDTGSGAHA-AHRGDEHFPLCSTFKVLAAGAVLARVD +RGEDRLDRRLRYEPREVVPYSPVSGPRAGGEMTIAELCEAAVTLSDNTAANLLLGTMGGP +AGLTGHIRGFGDATTRLDRTEPDLNEAASGDPRDTTTPLAMAETLRRLVLADALSPASRA +LITAWLVGCRTGDARLRAGLPKDWRIGDKTGSGENDTANDVAVIWPPRRAPLVLTVYLTG +ARTSPEARSATIASVARAVA--- +>[subseq from] Beta-lactamase n=2 Tax=Bordetella bronchialis TaxID=463025 RepID=A0A193G5K4_9BORD +------EYAALEQSHRRRLGVYAVDTGSGQEV-AYRAGERFAFCSTFKAILAAAVLAQDA +GKPGLLRQRVAYTKSDLVSYSPVTGEHAGAGMTIAELCAAAVQYSDNTAANLLLHRLGGP +AALTAFARQAGNASFRMDRYETQLNTAIPGDERDTSTPADMAGLLRALVLGDALPAPARA +QLKTWLVGNKTGAQRIRAAVPGGWAVGDKTGTGDYGSANDIGIIWPPSRPPIVMAIYTGS +RDKRAKADEGLIAEAARIAL--- +>[subseq from] Beta-lactamase class A n=1 Tax=Paraburkholderia silvatlantica TaxID=321895 RepID=A0A2V4TUB7_9BURK +--SLEKQLAAIEAQAGGRLGVAMLDTANGHVR-GWRMQERFPMCSTFKVLLASAVLTRKD +HGKEDLARKIVYSPAQVVSYSPVSGPRAGSEMTVAELCEAALTRSDNTAANLLLESIGGP +AAITAFARSIGDPVTRLDRNETTLNDAIPGDPRDTTTPAAMVANLRELLLGERLASVSRE +QLIAWLVANKTGDARLRAGLPKDWRVGDKTGTGDHGTANDVAIIWPTGRAPILVTAYLTG +ATASPAQRDAAIAQVGV------ +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola pv. fragariae TaxID=487822 RepID=A0A2N9D6I3_9XANT +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter agglomerans TaxID=549 RepID=UPI000B7AE852 +--TLKSQFETLENKSGGRLGVMVVDTSDGSEY-SWRGNERFPLCSTSKVMAVAAILKKNE +SDHSLLDKKIHINKSDMVNYNPITQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP +QQATHFARTIGDKAFRLDRKEPELNTAIPDDVRDTTTPSAMADTLNKLVLGTALKGEQRA +KLSEWMKGNTTGANSIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKDQAPIILTTYFTQ +KDKDAVARKDVLASAAKLVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium grahamii TaxID=1120045 RepID=A0A370KTR4_9RHIZ +-dEINRRMEALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQETLERRIVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP +AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD +KLAAWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVLWPPGHGAILVAAYVTQ +AKAPVSEINPVFAEVGKIVTD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. trifolii TaxID=386 RepID=A0A3E1BUP3_RHILT +--NIEKRLVALEKRTGGRLGVSVLDTQTSISF-GYRGDEAFPMCSTFKALAAGFALARAD +KGEESLDRRVTYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +KLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPAKELNPAFAEVGRMIVE-- +>[subseq from] class A broad-spectrum beta-lactamase OKP-B-40 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DE71B9D +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=UPI000459C232 +--QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAD +RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP +PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQPASRQ +RLAGWLLASQTGDTRLRAGLPAGWRIGDKTGVGGHGTNNDIGVIWPRDGAPVLISAYLTQ +SSASREAQNAVLAEVGRIAAH-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=A0A147GUH3_9BURK +--EAEAALQALDAGFDGALGVFALDTGTGATL-GHRAAQRFPMCSSFKAVLAAAMLGRSV +RQPGWLAERVRYTRAELVPYSPITERHVGEGMTVAALCAATVQYSDNGAANLLMARSGGP +QAVTAFARSQGDTVFRLDRIEPALNTAEPGDERDTTTPEAMARLLQRLVLGDGLPPPQRG +QLADWLRGNTTGARRIRAGMPALWTVGDKTGTGRHGSASDVGVVWRPGAAPLVLAVYTTR +PQPDAPADEAVIADAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. AD24 TaxID=1528693 RepID=UPI000B5DFCBD +--AIRQRLAQIEAESGGRLGVSIVDTSSGLHA-GLRTDERFPMCSTFKVLAAGAVLTRVD +RAQEDLARRVVFSQRDLVPNSPATSRHTRERMSIAELCKAAITLSDNTAANLLLATFGGP +AALTAFARDLGDGITRLDRIEPTLNEAIPGDPRDTTTPNAMLGNLRELVLGEHLSSSSRA +QLLAWLVANETGGARLRAKLPQDWGVGDKTGTGDHGTANDIAILWPPGRGPVLVAVYLTG +TNGDAARCNAAIAEVGALVVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1D3RIG5_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDSGMTIGEIAEAAIRYSDNTAGNILFNKIGGP +KGYEKALRRMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +NEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus sp. AG TaxID=2681969 RepID=UPI0012EB5E43 +--AIKDDFAKLEDKFDSKLGVFALDTGTNQTV-VYHPDERFAYASTHKALAVGALLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASIRYSDNTAANLILKELGGP +TGFKKILDEIGDNVTNPERYEPELNEVNPGETYDTSTPRALATSLQAFTLGDTLPAEKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGSGSYGTRNDIGIIWPPKGDPIVLAVLSSR +DKKDADYNDKLIAEATKEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=UPI0005E457E3 +--SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLVAAVLGHSQ +SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL +EMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRE +QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVVYFTQ +LKKAAEPRRDVLAAATEIVLAH- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=A0A0D0MS60_VARPD +-qDASAQLAALEAASGGRLGVVGFNTATGARV-QHRADERFAFCSTFKLMLAAAVLERSA +KEGGLLARRVNYSKGDIIANSPITEKNVATGMTVADLCAATIQYSDNAAANLLMKVIGGP +PAVTAFARSSGDDAFRLDRWETELNTAIPGDLRDTTTPAAMAASVERLVLGNALGTSQRE +QLKTWLLGNTTSKERFVAGVPAGWKVGDKTGAGSYGTNNDVGVLWPPAGAPLVLAVYLTF +PEKDAKVRNDVVASATRIAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Paracraurococcus ruber TaxID=77675 RepID=UPI001057FE9F +-----DAVARIEAASGGRLGLAVLDTGSGARL-AHRGAERFPLCSTFKLLAAAAVLARVD +AGEEWLDRLVRFGREALVTYSPATEPQAGGPMTLAALCEAAMTLSDNTAGNLLLAAIGGP +EGLTAFARRLGDPATRLDRIETTLNEARPGDPRDTTTPAAMLADLQALLQGDALSPAGRA +QLLAWLEGTRTGDTRIRAGLPAGWRFGDKTGSGDNGTTNDVGLFWPPGRPPVLFAAYLTQ +TAAPTDQRNATHAAIGRALA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mesonae TaxID=1193713 RepID=A0A3T0I6A4_9BACI +--QIHRKFADLEHKFDARLGVYAIDTGTNRTV-SYRPNERFAYASTFKALAAGALLQHYS +--LDQLDELVKYSREDIVTYSPVTELHVDTGMTLREVIEAAVRYSDNTAGNLLLNKLGGP +KGFETALRQIGDNVTQADRYETELNSAVPGDTRDTSTPKALAASLRAFAVSDLLSAEKRT +ILIDWMKGNATGDALIRAGVPNGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR +DTQNATYDNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=2 Tax=Marinobacter hydrocarbonoclasticus TaxID=2743 RepID=A1TZK3_MARHV +--SLIKTVKKVADDLEARVGFAAYDLESGQRW-EYHADQRFAMSSTFKTLACAALLHRVD +TGQANLARKVNVSESDLVTYSPITETYADGEMTLSDLCEATLTTSDNTAANLVLRELGGP +EAVTSFARHLGDDVTRLDRWETELNEALPGDNRDTTTPNAMVRNLQTLLLGDALSEPSRE +QLRDWLEGNQVADGLFRAAVPEGWVVADRTGAGGFGSRSITAVIWPPERQPIVVALYLTQ +TDASFAERNAAIAEIGEAIV--- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5YLB6_9BACT +--DAAARIAAIETRIGGRIGVAALDTSNDKHHlEYRAKERFPMCSTFKFLAAAAVLQRVD +EKKEKLERFVPYNAKDILEYAPVTKEHLNEGMTLGALCQAAIEQSDNTAGNLLLNAIGGP +AGLTDFVRTLGDRVTRLDRIEPELNSAIPGDERDTTTPAAISSDMQRLLLGDSLSETSRR +QLDDWLQRNETGGPMIRAGVPKTWSVGDKTGRGANGATNDIAIMRPPGRAPILLAIYSVG +STATANDRAAAIAEVTKVVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A0G8BZB2_9BACI +--TVNHSFAKLEKEFDAKLGIYALNTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGEVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Paraburkholderia unamae TaxID=219649 RepID=A0A328XQT9_9BURK +--ALENELAAIEAQAGGRLGVAMLDTANGQTR-GWRMHERFPMCSTFKLLLASAVLTRKD +RGKEDLARKVVYTQAQVVSYSPLSGPRAGGEMTVAELCEAALTRSDNTAANLLLESIGGP +PALTAFARGIGDPLTRLDRNETTLNEAIPGDPRDTTTPAAMLSDMRALLLGERLSAGSRE +QLIAWLVANKTGDARLRAGLPKDWRVGDKTGTGDRGTANDIAIIWPAGRAPLLVTTYLTG +ATASPAQRDAAIAKVGAWVAK-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000D13AFDE +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2DE94A +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMSATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKH0_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATALRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium gnaphalii TaxID=1010610 RepID=A0A512JEH2_9RHIZ +----EEVFAQIERSVGGRLGVAALEAGTGRGL-RYRAGERFPLCSTFKLLAAAAVLSRVD +AGQESLERRIAYTASDLVDYSPTTAARVTEGIPLADLCEAAITLSDNTAGNLMLSRIGGP +SGLTRYLRERGDTVTRLDRTEPALNEALPGDPRDTTSPDAMVANLDRFVLGDALATSSRA +RLQEWLLANRTGATRFRAGLPPDWRVGDKTGTGERGTANDVGLLYPPDGAPILAAVYLTE +STGSPEQRNASIAQVARTIAN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RKK2_9BACT +------QIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas parafulva TaxID=157782 RepID=UPI00041D9E9D +--DIDSDLSTVEHSFKVTLGVWAIDTASGKTV-AYRAEDRFAFCSTFKVILAAAILAKSA +EDQALLDRRITYAPDQLVTYSPITEQHVQAGMTVRELCAAALQYSDNTAGNLLLELVGGP +AGLTAYARTLGDPVFRSDRNEPSLNTALPGDPRDTTTPLAMGVTLQKLLLGSALGEDARQ +QLQGWLKGNTTGDKRIRAGVPQGWLVGDKTGSGDYGVANDVAVVWPPGKAPWIVVVFSRA +EAKASEWNNDAIAASMKAVA--- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-37 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A346ARK9_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRRELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QLVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI0006B304C0 +--ALARAVQEIEASVGGRLGVALLDMATGRQG-AHRGDERFPLCSTFKLVLAAHVLRRVD +QGQERLDRRITYGKSDLMEYSPATERHVDGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP +LGLTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSAAARA +QMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDIGLFWPPDRGAVMVSCYLTG +SPAPAEQRDAALARVGTLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=A0A0P0IUA6_KLEVA +-----EQIKQSESQLSGRVGMVEMDLASGHTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Lysobacter enzymogenes TaxID=69 RepID=A0A1J1E8D3_LYSEN +--ALRARLAELEKRSGGRLGVSALDTADGRRF-DVRGDERFAMCSTFKFLLAAAVLRKAD +RGELDMQQRLAVPKSALISHSPITTPIAEAGASLAQLCEATMTISDNAAANLLLPLVGNP +AGLTRFLRGIGDSVTRLDRNEPELNTALPGDPRDTTAPNAMLASMRTLLLGDALSAASRR +QLTDWLIANQTGDKRLRAGLPKDWRIGDKTGSGN-GTTNDIAIVWPQGRKPVFITTYLTQ +AQGEDDARSAILADAARALAQHw +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus brevis X23 TaxID=1200792 RepID=A0A291BFL9_BREBE +--AMDQKFAALENKFDVRLGVYAIDTETDVVV-AYREDERFAFASTYKALAAAAVLHQKP +--LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP +KGFESALRQIGDSVTTSERYETELNEAKPEDIRDTSTPKALATNLRAYTVGDVLSSDKQT +ILIEWLKGNTTGDKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR +DKQDATYDDALIAEATKVAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD5F280 +-nDINRQLASLEKRTGGRLGVSVLDTKSNASF-GHRQDERFAMCSTFKALAAAFVLARVD +KGQETLGRRIVVSKADLHAHSPVAEKHVGNGMTVGELCDAAVTYSDNAAANLILASFGGP +AGLTAWLRSIGDETTRLDRTEPALNEAKPGDPRDTTTPAAMMRTLGKLLLEDVLSPSSRD +QFAAWLVANRTGDRRLRAGLPAKWTIGEKTGTSGHGEAGDVGFMRPPKGQTILASVYIAE +APKPVKELEPIFAEVGKLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Azohydromonas sp. 13393 TaxID=2590212 RepID=UPI0012FCF95F +--ALSRALPVMEERLGARLGVHILDTHTGHQW-THRAGERFPMCSTFKVLACAAVLARVD +AGADNLKRRIRFQGSDLVTYSPVTEPHAGRELLLSELCEAAMTRSDNTAGNLILRSLGGP +AAVTAFARSLGDEATRLDRWETALNEARPGDPRDTTTPAAMSTCLQALVLDQRLAPESRG +QFVRWLLANRTGDARLKAGLPATWRIGDKTGSGDFGTANDVAVIWPPGRSAVIASVYITQ +TVASFDDRNAAIAEIARVL---- +>[subseq from] Beta-lactamase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3LN01_9BURK +-----DAWAAIERSSGGRLGVAVMQ-ADGRID-GHRLDERFPMCSTFKWLAAAHVLHRVD +RGEERLDRRIRYGREVLLPHSPVTERHVGDGMTLAELCHATITISDNAAGNLILASFGGP +AGLTRYARGLGDEVTRLDRWETELNEARPGDPRDTTSPRAMARLLHATLVGDALSPRSRT +QLAQWLEATSTNGQRLRAGLPPGWRMGSKTGTGARGTTNDVGIYWPPGRPPVVVAVYLTQ +SEAPEAARNGAVAQVARRVH--- +>[subseq from] Beta-lactamase class A n=1 Tax=Paraburkholderia sp. BL8N3 TaxID=1938808 RepID=A0A4R1IIP0_9BURK +--SVDARFADLERASGGRLGVCAIDTANGAQI-SYRSDERFPFCSTFKLMLAAAALAHGT +LVAGFMQQRVRYARRDLVTYSPVSSRHVESGMTVEELCAAAIQYSDNTSANLLMNMLGGP +AAVTAFARSIGDAEFRLDRRETELNTAIPGDARDTSTPAAMAQSVRALCVGDALPAPQRA +QLQDWLRGNTTGAKRIRAGVPPGWQVGDKTGTGERGTANDVGVLWLAARKPVVLAVYHTQ +QVVHAQPNDAIIAAATRVVMRAf +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F23DDE8 +-----EQIKQSESQLSGRVGMIEMDLASGRAD-RRRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2P1BP57_KLEPN +------KVKDAEDQLGARVGYIELDLNSGKIXeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGXXQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRXLCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIXDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium 65-37 TaxID=1895711 RepID=A0A1Q3KN46_9PROT +-----SKFSDLEARNGGRLGVAAFDTTSGRRV-GHRSDDRFPICSTFKLPAAALVLARVD +RGEEQLGRRVVYSEKDIVVNSPVTASHAGAGLSMAELCEAAMTQSDNTAANLMLASFGGP +AALTAYLRSLGDMTTRLDRIEPDLNEALPDDPRDTTTPAAMVATMERLLLRAVLSASSRK +MLTGWLVANKTGDKRLRAGLPADWRVGDRTGTGANGTANDVAIVWPGDDPPILMAVYYTG +STISDEARNTVVAEAGSIVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKE3_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYAPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEE463E +--AMYKNFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +NEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Comamonadaceae bacterium SCN 68-20 TaxID=1660161 RepID=A0A1E4LJ31_9BURK +--ALLRALRGIEQGVGGRLGVAALDTGTGRLA-AHRGGERFALCSTFKLLLAAQALHRVD +RGVEQLEHRIAYGQADLLEYAPVTRPHAGGALTVAELCEAAMAWSDNTAANLLLARQGGP +QALTDWLRTLGDPATRLDRNEPALNDVPPGDVRDTTTPEAMARTLQAVALGEALTPASRE +RLQGWMLGCRTGDQRLRAGMPPGWRIGEKTGTGPRGTSNDIGVLWPPGRAPVALACYLTG +STADGARRDAAIAEVGRRVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. X2(2017) TaxID=2025586 RepID=UPI000BA84313 +--ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNKRFAYASTYKALAAGAVLQQNS +--IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP +KGFEKALRQIGDNVTVANRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK +ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR +DKKDATYDNELIAQAAKVTIN-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A2S4FQU5_9BACI +--ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNKRFAYASTYKALAAGAVLQQNS +--IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP +KGFEKALRQIGDNVTVANRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK +ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR +DKKDATYDNELIAQAAKVTIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00144219AC +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLTLGSVLTEASSG +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2C4ZEF9_9BACI +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009E19A05 +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDILSTEKRN +LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNQ +GKEDAKYDDKLIAEATKIVLH-- +>[subseq from] Beta-lactamase n=1 Tax=Idiomarina aestuarii TaxID=624146 RepID=A0A2T4D0J2_9GAMM +--RLLDAIHTVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAVLHKVD +RESETLDRRITYRSDDLVTYSPITEKHVDSGMTIGELCEAALHLSDNTAANLVLDVLGGP +DVLTAYLRDIGDDVTRLDRIEPDLNAATPGDARDTTTPNAMRATLTYLLFGDALSLESRQ +LLEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPERKPVIAAIYITQ +TSASMGERNAAIADLGQEIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. Cy-639 TaxID=2608360 RepID=UPI0014206914 +-nSLQRQLQQLEHAAGITLGLWALDTGSGKRL-AYRADKRFAFCSTFKAVLVGAVLHKSQ +TDPKLLERQIPYDIGQLVVYSPVTEKHTGAGMTVAELCAAALQYSDNTAGNLLLELVGGP +AGLTAFARRLGDPSFRLDRNEPTLNSALPGDPRDTTTAQAMGVTLQRLLLTNGLPAGAQD +QLRDWLKGNTTGDSRIRAGVPQGWVVGDKTGSGDYGVANDVAIIWPKGRAPWILVVFSRA +QEKSAAWNSEVIAQATRVVVDTw +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MZ04 TaxID=2559236 RepID=A0A4R9EYL7_9ACTN +--EARRRLRELEKDYPGRIGVHALDTGSGATV-GHREHERFAIASTFKVLAAAEILRRAD +KEPGLLDVLVEYTRDDLVTASPRTELHLETGMTVRELCDATITYSDNAAANLLMRRMGGP +AGITAFARSLGDSRTRLDRWEPELNTNIPGDPRDTTTPAAMTENLRRLVLGDALHPLDRG +QLTRWLLENTTGDKRIRAGLPKGWRVGDKTGTPAYGGVNDVAVTWPPDRAPLVISVYTTR +LDPDTPGEDRIAEDITRVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00102F6903 +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGNTRLDRTEPTLNEGQKGDPRDTTTPDAMLDTVGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPVKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010324A59 +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGSDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGNTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTVGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL53_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYXQNDLVEYSPVTEKHXTDGMTVRELCSAAITMSDNTAANLXLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAXIGASLIKH- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF4F68C +--TVNHSFAKLEKEFDAKLGIYAFDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IENLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +NEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFTLGDVLSTEKRN +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium phaseoli TaxID=396 RepID=UPI0013CB744D +-dNIERRLAALEKRTGGRLGVSVLDTDTSISF-NYRGSEAFPMCSTFKALAAGFVLARVD +KGEESLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTAPDAMLDTLGNLTLGSILTEASSD +RLIAWLVASTTGGERLRAGLPKEWNVGDKTGTGPNGSLGDIAVIWPPNRGPIVAAVYIAE +ATAPAKDLNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Labrenzia alba TaxID=311410 RepID=A0A0M6Z0S0_9RHOB +-----ETAQDVENRLSARIGVAVVETETGRTW-NYRGDERFPLNSTFKAFLCAALLDAGD +KGEIDLAQSVTVHDSDLVAYSPVTEKRVGGDFTLLELCEATATISDNAAANLVLKELGGP +DSLTRFMRRIGDKTTRLDRFEPELNSAIPGDERDTTTPLAAASSLQKLLLGDELTAASRK +QLTSWLVGNKVGTSTLRAGLPKEWIVADKTGAGDYGSRSNIAVIWPENRAPVVIAVYITQ +TKASFEDRNRAIADIARALVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B4BC2C5 +-qATHKEFSQLEKKYDARLGVYAFDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDNRDTSTAKAIATNLKAFTVGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] Class A beta-lactamase Bla1 n=2 Tax=Bacillus albus TaxID=2026189 RepID=A0A654SAU5_9BACI +-qATHKEFSQLEKKYDARLGVYAFDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDNRDTSTAKAIATNLKAFTVGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0014423394 +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSESFPMCSTFKALAAAFVLARAD +KGEENIDRRVSYGRDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD8F174 +-dEINRRMDALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP +EELTKWLRTLGDRSTRLDRWETALNEAKDRDPQDTTTPDAMVDTLGNLTLGSALSEPSRD +KLVAWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYLTQ +AKAPVSEINPVFAEVGKIVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Caballeronia glathei TaxID=60547 RepID=A0A069PUZ8_9BURK +--SVDARFADLERASGGRLGVCAIDTANGAQI-SYRSDERFPFCSTFKLMLAAAALAHGT +LVAGFMQQRVRYARRDLVTYSPVSSRHVESGMTVEELCAAAIQYSDNTSANLLMNMLGGP +AAVTAFARSIGDAEFRLDRRETELNTAIPGDARDTSTPAAMAQSVRALCVGDALPAPQRA +QLQDWLRGNTTGAKRIRAGVPPGWQVGDKTGTGERGTANDVGVLWLAARKPVVLAVYHTQ +QVVHAQPNDAIIAAATRVVMRAf +>[subseq from] Beta-lactamase class A n=1 Tax=Burkholderia sp. TNe-862 TaxID=416944 RepID=A0A1G6HBN2_9BURK +hgALEKQLAAIEAQTGGRLGVAMLDTASGRAQ-GWRMHERFPMCSTFKLLLASAVLTRKD +HGGEDLARKIVYSHAQVVSYSPVSGPRAGGEMTVAELCEAALTRSDNTAANLLLESIGGP +AAVTAFARSIGDPVTRLDRNETTLNEAIAGDPRDTTTPAAMLADMRELLVGERLSAASRE +QLIAWLVANQTGDARLRAGLPKDWRTGDKTGTGDHGTANDIAIVWPVGRAPILVATYLTG +ATASPAQRDGAIAKVGAVVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium anhuiense TaxID=1184720 RepID=UPI0007BE9995 +-dDIQHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSSFKALAAGFVLARVD +KGEEKLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVSVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPEAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVTELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00141ABF4F +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A5C1G375_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVKAf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000409F1E7 +-tEIKADFAKLEDQFDAKLGVYAVDTGTNQTV-TYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAQNLILKQIGGP +DSLKKALREIGDDVTNPERYEPELNEVNPGETHDTSTAKALAKSLQAFALEDTLPKEKRE +LLIDWMKRNTTGDALIRAGVPEGWEVADKTGSASYGTRNDIAIIWPPKGDPIVLAILSSR +DQKDAKYDDKLIAEAAKEVIKAf +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Yersinia pseudotuberculosis TaxID=633 RepID=UPI00067B8013 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITSSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase KPC-10 n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=C6JUP9_ACIBA +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVRWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHZ0_KLEPN +-----EQITLSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDERLDRRIRYPQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPAAMAERNQQIAKIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Marinobacter TaxID=2742 RepID=A0A5P9EKB4_9ALTE +hnALIKTVEKVADDLEARVGFAAYDLESGQRW-EYRADQRFAMSSTFKTLACAALLHRVD +TGQANLARKVNVSESELVTYSPITEKHADGEMTLSDLCEATLTTSDNTAANLVLRELGGP +EAVTSFARHLGDDVTRLDRWETELNEALPGDNRDTTTPNAMVRNLQTLLLDDALSEPSRE +QLRDWLEGNQVADGLFRAAVPEGWTVADRTGAGGFGSRSITAVIWPPECQPIIVALYLTQ +TEASFEERNAAIAEIGEAIV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=A0SXM1_SALTM +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A1Y6B165_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q6REX4_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKNGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillus mucilaginosus (strain KNP414) TaxID=1036673 RepID=F8F5G2_PAEMK +--SAKQPFAQLESEYKARLGVYAVDTGTGRTI-EYRPDERFAYASTFKALACGAVLKAKP +--LEGLEDRVTYTSGELVTYSPVTEKHVSTGMTLRELCDAAIRYSDNTAGNLLLKQLGGP +KGFEAALKEAGDAVTKAERYETELNEAVPGDDRDTSTPRALASSLRAYTLGDALSADKRD +VLTDWLRRNTTGGELIRAAVPEGWVVGDKTGAGSYGTRNDIAVIWPPDGPPIVMAVLSSR +DTKDSAYDNALIAKAAKAALD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Aeromonas hydrophila TaxID=644 RepID=A0A649UHL3_AERHY +-------IKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLAIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A649UIF6_ACIBA +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLSAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEH- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D614_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPVSMAERNQHIAGIGAALIEHw +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000E2ACA57 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPVSMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Roseomonas oryzae TaxID=1608942 RepID=A0A5B2TK97_9PROT +---LEGAFARIEAEVGGRLGVAVLDTGGGHYA-GHRADERFPLTSTFKLLAAAATLARVD +AGKERLDRRVRFGRDKLVTYSPVTEPHAGGNMTVAALCEATVTLSDNTAGNLLLEGLGGP +AGLTQWLRSIGDSTTRLDRWETALNEARPGDPRDTTTPAAMLGDLQLLLLGEVLSAGSRA +RLTQWLRDNKTGDARLRAGLPQGWQAGEKTGSGGLGSTNDAGLIWPPGGAPVLVAAYLTG +SAAPLAAREAALAGVARAIT--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011559FC9 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDBB966 +-dEINRRMDALEEAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP +AELTKWLRTLGDRSTRLDRWETALNEAKDDDPQDTTTPDAMVDTLGNLTLGSALSEPSRD +KLVAWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYVTQ +AKAPVSEINPVFAEVGKIVAD-- +>[subseq from] Beta-lactamase n=2 Tax=Stigmatella erecta TaxID=83460 RepID=A0A1I0L484_9DELT +------RLAELERRHGGRLGVAVLDTASGARV-LHRADERFPLCSTFKFLAAAQVLARVD +RGEEQLGRRIVFSEADLVSYSPVTKEHVGGDMTLEAICEAAITLSDNTAGNLLLDSFGGP +AALTRYVRTLGDRKTRLDRRETELNEAKPGDPRDTTTPAAMLQDMQRLLVGDALSAGSRE +RLVAWLTASKTGAKRLRAGVPPDWRAGDKTGTSGNGVVNDIAIFWPPDRAPLLVSAYYRG +PEG---TGDAVLEAVGRLVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium bangladeshense TaxID=1138189 RepID=UPI0007E5BB87 +--NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPAAMLDTLGNLTLGSVLTEVSCN +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATVPVKDLNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3YA68_KLEPN +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora pisi TaxID=589240 RepID=A0A495JS97_9ACTN +------EFGHLEAKFGARLGVYALDTGSGRTV-EHRANERFAYASTFKALAAGAVLAETS +--TAELDQVVRFTAADLVTYSPVTEKRVETGMSLRELADAAVRYSDNTAGNMLLKRLGGP +DGLERALRGLGDRTTDPERTETSLNEATPGDTRDTSTPRALVGDLRAYVLGEALDAEDRA +VLTGWLRSNTTGDKLIRAGVPAGWVVGDKTGSGGYGTRNDIAVVWPPDREPIVLAILSTR +DKQDATYDDALIAEAARVVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. HB1 TaxID=1678678 RepID=UPI0006B3EDCB +--AIRARLEEIEAQSGGRLGVSIVDTTSGLHA-GLHADERFPMCSTFKLLAAGAILARVD +GGEEDLQRRIVYPESELVPYSPATSKHTRERMSIAELCKAAITLSDNTAANLLLQSFGGP +AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNMRELLLGERLKSSSRV +QLLAWLAGNETGGARLRAKLPKDWGVGDKTGTGDHGTANDVAIFWPPGRGPILVAVYLTG +TAGDAARNNAAIANVGALVVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKE4_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNGERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=5 Tax=Bacillus TaxID=1386 RepID=A0A2A6FZA2_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase OXY-2 n=1 Tax=Methylobacterium bullatum TaxID=570505 RepID=A0A679J068_9RHIZ +--DLADRFAQIEEASGGRLGIGLLDTGSGTQA-AHRGGERFPMCSTFKVLAAGAVLARVD +RGEDGLDRRLRYEPREVVPYSPVSGPRAGGEMTIAELCEVAVTLSDNTAANLLLGTMGGP +AGLTGHIRGFGDATTRLDRTEPDLNEAAPGDARDTTTPLAMAETLRRLVLADALSPASRA +LITAWLVGCRTGDARLRAGLPQDWRIGDKTGSGENDTANDVAVIWPPRRPPLVLTVYLTG +ARTSPEARSATIASVARAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas massiliensis TaxID=522492 RepID=UPI00058D22E0 +-----VALAALEREFNGRLGLCALDPRHGRAL-RWRADEAFPLCSTFKVVLAAAILKQVG +--LSGLGRRVRYQQSDLVTYSPVTEQHLATGMTLAELCAAGLQYSDNTAGNLLLREVGGP +AGLTAFARQLGDNSLRLDRWETELNSAIPGDPRDTTTPGAMAATLQTLLLGQGLDARLQA +QLTDWLLANTTGDARIRAGVPHGWKVADKTGSGDYGTANDVGVIWPAKDRPVVIALYSTQ +PAAAAEPRSDVLARMARIVAN-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-54 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6B9KGH5_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRSEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI001030061A +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVIVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAVLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces tendae TaxID=1932 RepID=A0A5P1YE31_STRTE +------NLTALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAALLDRRP +--GARLDERITYGAADLVPYSPVTEKHTGKGMTVRELCDAAVRYSDNTAANLMLRELGGP +RALTAYVRGLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVLGDALPGAGRA +QLTDWLVRNTTGDRRIRAGAPRGWTVGDKTGTGEWGRANDAAVLWPGNGSPMVLSVLTER +PDRDAAASDELVAEAARRVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium aegyptiacum TaxID=1764550 RepID=UPI0007E59A51 +--NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGGEAFPMCSTFKALAAGFVLARVD +KGDEKLDRRVTYGRDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +PALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +KLIAWLVASTTGGERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATVPAKELNPIFAEIGKMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BED92FC +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGALLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPEGWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009B500B7 +--ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNKRFAYASTYKALAAGAVLQQNS +--IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP +KGFEEALRQIGDNVTVANRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK +ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR +DKKDATYDNELIAQAAKVTIN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKE0_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEEHFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Class A beta-lactamase SHV-179 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=V5N016_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMNTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus formosus TaxID=54913 RepID=A0A4Y4I1X1_9BACL +--AMDQKFAALENKFDARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP +--LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP +KGFEAALRQIGDGVTTSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGNVLPSDKQK +ILIEWLQGNTTGAKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSKR +DKQDAAYDDALIAEATKIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Photorhabdus khanii NC19 TaxID=1004151 RepID=W3V4K1_9GAMM +--SLHQQLAELENRTKGRLGVTLINTANGQEI-QYRGNERFPFCSTFKLMLVAAVLHKSM +SQSELLAKHINYSESDLQSYAPIARKNLNQGMNITQLCAATLQYSDNTAANLLIKELGGL +AAVNHFAQGLGDRAFRLDRWEPDLNSAIPDDPRDTTTPAAMATSVKKIVLGETLAAPQRE +QLVGWLKGNTTGDASIRAGTPDGWVVGDKTGGGDYGTSNDVAILWPPEGSPVVLAVYFTQ +HQKDAESRRDVLASTTRLVMKH- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BED7D9D +----KHHFVKLEDKFDARLGVFALDTSTNQTV-TYRADERFTYASTSKALAVGALLQQKT +--IEDLNQRITYTQDDLVNYNPITEKHVDTGMTLKELCDAALRYSDNTAMNLILKQIGGP +NGLEKALRDVGDNVTMPEQFEPELNEVKPGETHDTSTPRALATSLQSFTLGDVLPIEKRE +LLIDWMKRNTTGDSLIRAGVPKGWVVADKTGSGSYGTRNDIAIIWPPKGDPIMLAILSSR +DKKDANYNDKLIAEATKEVINAy +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A059X6G7_9BACT +--TLKSQFETLENKSGGRLGVTVVDTSDGSEY-SWRGNERFPLCSTSKVMAVAAILKKNE +SDHSLLDKKIHINKSDMVNYNPITQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP +QQATHFARTIGDKAFRLDRKEPELNTAIPDDVRDTTTPSAMADTLNKLVLGTALKGEQRA +KLSEWMKGNTTGANSIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKDQAPIILTTYFTQ +KDKDAVARKDVLASAAKLVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=Q6EH44_PROMI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAL-GPDGKPSRIVVIYTTG +SQATMDEANRQIAEIGASLIKHw +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-39 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3G3MDR1_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSTIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter denitrificans TaxID=666685 RepID=A0A2W5MUQ1_9GAMM +-----ERLRELERADGGRLGVAVLDTASGRFA-GWREDERYPMCSTFKFLLAGAVLARVD +RGEFGLDRRIPISRDDLIAHSPVTERHVGPALTVAQLCEATMTQSDNAAANLLLPLVGEP +AGLTAVLRSWGDATTRLDRPEPHLNDVPPGDTRDTTTPRAMTEHLRHLVLGNTLTPASRT +QLTAWLVANRTGDHRLRAGLPKDWRVGDKTGSGP-GTTNDVAVLWPPGRAPLLVAAYLTG +SPQADDRRNATLAAVAREIA--- +>[subseq from] Beta-lactamase n=1 Tax=Metakosakonia sp. MRY16-398 TaxID=2487150 RepID=A0A348DKF8_9ENTR +-----ETVKKAEDQLNARVGYAELSLANGQMLgSYRPQERFPMMSTFKVLLCGAVLSRVD +AGQEQLARRIQYRKQDLVAYSPVTEKHLTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP +SELTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQMLRQLLNGKILTPASQQ +QLMAWMEADKVGGPLIRSVMPAGWFIADKTGAGERGSRGIVAALGPDGKPARIVVIYITE +TQATMDERNKKIADIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas entomophila TaxID=312306 RepID=A0A3S8UPE7_9PSED +-sSLAHELEALEHSLDVTLGLWALDTGTGKIV-SYRAGERFAFCSTFKVVLAAAILAKSA +DDRGLLDRRITYSEDQLVVYSPVTEKHVGDGMTVSALCAATLQYSDNTAGNILLEQVGGP +VGLTAFARNLGDPAFRLDRNEPELNTALPDDPRDTTTPLAMGMTLQKLLLGNSLAEAGRL +QLQEWLKGNTTGDKRIRAGVPQGWVVGDKTGSGDYGVANDVAVIWPPGKAPWILVVFTRG +QQKASSWSNEAISSSARAVVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000B43A3BE +----NHDFAKLEEEYDAKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNQKVTYTREDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAANLILTQLGGP +AGFKKALDKIGDHVTNPERFEPDLNEVNPGETHDTSTPKALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDTLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKEDPIVLAVLSSR +DKKDADYNDKLIAEATKVVIK-- +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=unclassified Raoultella TaxID=2627600 RepID=UPI00135A7F26 +heATVKQVKAAERLLEARVGYAELDIASGRLLtSYRPGERFPMMSTFKVPLCAAVLARVD +AGEEQLDRRVRYRQQDLVEYSPVTEKHLADGMTVAGLCAAAITLSDNTAANLLLASVGGP +QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLSGSVLSAASRQ +QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMKERNRQIAEIGETLVKHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus idriensis TaxID=324768 RepID=UPI0012B0C2F3 +----NHDFDKLEEKFDAKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNQRITYTREDLVNYNPITEKHVDTGMTLKELSDASIRYSDNTAANLILKQLGGP +TGFKKALEEIGDNVTNPERYEPDLNEVNPGETHDTSTPRALAASLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLSVLSSR +DKKDADYNDELIAEATKEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0014414B05 +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSESFPMCSTFKALAAAFVLARAD +KGEENIDRRVSYGKDKLVDYSPISEKHAGADMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. GZT TaxID=936600 RepID=A0A154B6A4_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAIYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=BLAB_PROVU +-nTIEEQLSTLEKYSQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE +KQAGLLDKNITIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP +AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPKNHAPLILVVYFTQ +QEQDAKYRKDIIVKATEIVTK-- +>[subseq from] class A broad-spectrum beta-lactamase OKP-B-34 n=1 Tax=Klebsiella TaxID=570 RepID=UPI000B40E904 +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAVIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=Q5PU78_KLEPN +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAVIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Massilia armeniaca TaxID=2072590 RepID=A0A2R4CAG3_9BURK +------PFQRIEDRWGGRLGVAAIDTGNGAVV-GHRQDERFPFCSTFKTVVAAAVLARSV +TEPGFLDKRLRYTQADIKPHSPVSEKHVASGMTAAELCAATIQYSDNAAANILMRELGGP +AAITAYARSLGDTTFRLDRWETELNSAIPGDQRDTTTPLAMARTLEKLLVGDGLPPAQRQ +QLKDWMVGNTTGDTRIRAGVVKGALVADKTGTSGYGVANDIGVIYLPERAPIVLVVFTHG +TDERAEAQSEPVAEATRVAV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKF4_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEMHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=H6UQJ9_KLEPN +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAIIWPENHAPLVLVTYLPN +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas cremoricolorata TaxID=157783 RepID=UPI0009DD54D8 +--SADSRFQRIEREHGITLGVFALDTGSGRQL-AYRADQRLPMCSTFKVMLAGAVLQRSQ +TERELLARVIRYPASALVVYSPVTERQVGQGMRVAELCAAALQYSDNTAANLLLELLGGP +AELTAFARRLGDPVFRLDRIEPDLNSALPDDPRDTSSAQAMALSLQRLALGDALDHAGRG +QLQTWLKGNTTGAKRIRAGVPAGWTVGDKTGSGDYGVANDVALLWPAGRAPWVLAVLSRS +AEAKAAWRDAALAEATRVVVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010321A1A +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFELARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=I7AP36_KLEPN +--DVQQKLAELERQSGSRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAE----------------- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium vallis TaxID=634290 RepID=A0A3S0Y7Q1_9RHIZ +-dDIQRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGEESLDRRVTYGKEKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +PALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTAPDAMLDTLGNLTLGSILTEASCD +KLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPNRGPIVAAVYIAE +ATVPAKDLNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A1I2WXL5_BACME +----KHHFVKLEDKFDARLGVFALDTSTNQTV-TYRADERFTYASTSKALAVGALLQQKT +--IEDLNQRITYTQDDLVNYNPITEKHVDTGMTLKELCDATLRYSDNTAMNLILKQIGGP +NGLEKALRDVGDNVTMPERFEPELNEVKPGETHDTSTPRALATSLQSFTLGDALPVEKRG +LLIDWMKRNTTGDSLIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPPKGDPIMLAILSSR +DKKDANYNDKLIAEATKEVINAy +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. F56 TaxID=1581850 RepID=UPI0009F41ECD +--ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNKRFAYASTYKALAAGAVLQQNS +--IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEVCEAAIRYSDNTAGNLLFKKLNGP +KGFEEALRQIGDNVTVANRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK +ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR +DKKDATYDNELIAQAAKVTIN-- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=A0A5C5AVW4_9BACI +-qATHKEFSQLEKKFDARLGVYAINTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia sp. SOS3 TaxID=1926494 RepID=A0A1L6I5G8_9BURK +--ALSTALRNIEAERGGRLGVAVLDSQTGKSA-GYRADERFPMCSTFKLLAAAAVLSRID +RGDDRLDRRIRFAASDVVVNSPVTQNRSAPEMTLAEICEAAMTYSDNTAGNLMLTSIGGP +KALTAYARSLGDTVTRLDRTEPELNEALPDDPRDTTSPAAMLSNLRDLVTGNALQRESRD +RLSGWLIGNKTGGSRLRAGLPREWRVGDKTGAGERGTTNDVAVVWPSEGRPLFISIYLTG +DRIDGKHQNATIASVGAALA--- +>[subseq from] KPC-5 protein n=7 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A0E3ZB52_ECOLX +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVRWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A179BY70_RHILE +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFALARTD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCAAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=BLAC_BACAM +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKQKP +--IEKLNDVIRYTKEDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILTKR +FTKDAEYDNALIAEAAKVALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Phytobacter sp. SCO41 TaxID=1756993 RepID=UPI000D500151 +-----ETVKKAEDQLNARVGYAELSLANGQMLgSYRPQERFPMMSTFKVLLCGAVLSRVD +AGQEQLARRIQYRKQDLVAYSPVTEKHLTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP +SELTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQMLRQLLNGKILTPASQQ +QLMAWMEADKVGGPLIRSVMPAGWFIADKTGAGERGSRGIVAALGPNGKPARIVVIYITE +TQATMDERNKKIADIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0013C5DB7C +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFALARTD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCAAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRVIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter sp. Bisph2 TaxID=1274400 RepID=UPI00057C08D0 +-----ETVKKAEDQLNARVGYAELSLANGQMLgSYRPQERFPMMSTFKVLLCGAVLSRVD +AGQEQLARRIQYRKQDLVAYSPVTEKHLTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP +SALTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQMLRQLLNGKILTPASQQ +QLMAWMEADKVGGPLIRSVMPAGWFIADKTGAGERGSRGIVAALGPDGKPARIVVIYITE +TQATMDDRNKKIADIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Bordetella genomosp. 5 TaxID=1395608 RepID=A0A261TL50_9BORD +----QRLLARLEARDGGRLGVSVLDTGSGWAL-AHRSDERFPMCSTFKWVAAAAVLARVG +RGQDSLDRHIRYGATDLVPYSPVTKPQVAQGMTLGALCEAAVVWSDNTAANLMLSTLGGP +PGITAYARSQGDDQTRLDRIEPALNEAQPGDPRDTTTPQAMLRLLRRVLLEGGLEAPQRD +QLTAWLRGCRTGYTRLRAGLPADWIVGNKTGAGEHGTNNDVAVIWPPRGAPILVTAYLTN +SPASRDAQNALLAETARIVVH-- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. FWC2 TaxID=69664 RepID=A0A2G5QSZ2_9CAUL +--ALNSRINELEQRSGGRLGVAVLDTHDGRRF-AWRGDERFRMCSTFKMPLAAAILRRVD +QGRERLDRRVTYGREVLMGNSPVVEKHLDRGMTIGELCAATITYSDNAAANLLLDALGAP +TDLTRFLRALGDQTTRCDRREPELNTGAPDDPRDTTTPTAIAETWKTLLTTDTLSAASRK +QLTAWVVANRTGGKRLRAGLPRSWTVGDKTGNNGQDQTNDIAVIWPPKRKPLFVAAFHDQ +GSADDDVRSAVLADVARAVVS-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0G8F0L4_BACCE +--TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000DE58443 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNFKDFTVGNALPDDKRK +VLTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=Q5GJ46_RAOOR +heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD +TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARILRNLLTGRVLSPASQQ +QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA +TPASMDERNKQIAAIGETLVRHw +>[subseq from] Beta-lactamase n=1 Tax=Bordetella sp. H567 TaxID=1697043 RepID=A0A1B2R9I9_9BORD +--AIDAEFARLERSHQRRLGLYALETGTGREI-AYRANERFAFCSTFKAVLAAATLAQDA +AQPGLLERRIIYTQHDLASYSPVTKERLGGGMTVAELCAAAVQYSDNTAANLLLHRLGGP +RALTAYARDVGNKSFRLDRYETALNTAIPGDERDTSTPADMGRMLEALVLGNALPAEART +RLKTWLLGNKTGDHRIRAAVPAGWQVADKTGTGDYGSANDFGIVWPPGRPPIVLAIYTGS +RDTHAKADESLIAEAARIAI--- +>[subseq from] Beta-lactamase n=2 Tax=Geobacter lovleyi TaxID=313985 RepID=B3E6E6_GEOLS +----GEQISMIEKRHGGRLGIAALNTATGMRI-EYRSAERFAMCSTFKFILVAAVLKQVD +EKKISLDRGIPYTTADLLDWAPITKKHVSDGMTVERLCAAAIEYSDNTAANLLLDLLGGP +KAVTAYARSLGDSVTRLDRNEPSLNDNLPNDDRDTTSPSSMVETMNKVLSGHALSPSSRK +ILENYLLANTTGANRLRAGIPLDWRVGDKTGTGSNGAVNDIAVMWPPDRSPIFVAVYYSG +SPSPNSDREAVLAEVGKLIAIEf +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=X5JZE0_ENTCL +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D612_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0013DC0172 +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARGD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +KLIAWLVASATGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Aureimonas sp. AU40 TaxID=1637747 RepID=UPI000782672C +--ALNALLADIEKRFSARLGAFVHDTGSGRRW-ARRADERFPLCSTFKVVAAAGLLARVD +RGEADLSRRVVIAKSDLVTYSPVTEKQVGGEMTLAEICAAAITRSDNTAGNVLIDQLGGP +EGVTRFARSLGDETFRLDRRETDLNEATPGDPRDTTSPAAMTKTLHALLFEDHLKDVSRW +RLAEWMVANQTGGAKLRAGLPKSWHIGDKTGGGDHGTMNDIAVLWPPEGAPIVASLYLTE +TEASFDERNAAFAEIGNALA--- +>[subseq from] Beta-lactamase n=1 Tax=Neptuniibacter sp. Phe_28 TaxID=1795871 RepID=A0A136H9X2_9GAMM +hrSLIQTVERIAGEIEAQVGFAAYDLESGQRW-EYQADQRFAMSSTFKTLACAALLHRVD +AGQESLDRRVSFSESDLVTYSPITEKHAGGQMSLADLCEAALTMSDNTAANLVLQALGGP +EKVTLFARVLGDDVTRLDRWETELNEAVPGDNRDTTTPNAMVKNLHNLLLGDVLSRKSRD +QLYDWLKRNQVADGLFRAAVPEGWIVADRTGAGGFGSRSITAIFWPPERQPIVVALYLTQ +TEASFSERNKAITEIGEAIV--- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001082C8FB +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGYARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia sp. TaxID=1926495 RepID=A0A522MU36_9BURK +-kAIESELAAIERSVDGRLGVAILDLETGMRA-GHRAGERFPTCSTFKLMLAAQVLARVD +HGQERLDRRIVFGADRIERYAPVASKHIGEPMTVGELCDAIVTMSDNTAANLLLDTVNGP +AGLTAFMRQLGDTVTRLDRNEPSLNEAIPGDPRDTTTPLAMLGNVQTVLLGNALTAASRA +RLLAWGAGNRTGDARLRVGVPRAWRVADKTGTGERGTTNDIGLLWPEDGAPIVVTAYLTQ +TGAPARARDAAIADIARAISKH- +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax oryzae TaxID=862720 RepID=UPI000AF5648E +---FARAVQEVEASVGGRLGVALLDVATGRQD-AHRGDERFPLCSTFKLVLAAHVLRRVD +QGQERLDRRITYRKSDLMEYSPATERHVDGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP +LALTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSAAARA +RMLAWLVGNRTGDRRLRAGMPEGWRVGEKTGTGPRGTSNDIGLFWPPDRDAVMVSCYLTG +SPAPAEQRDAALARVGALAA--- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. (strain B510) TaxID=137722 RepID=D3NZG0_AZOS1 +---LAAGMAALEERSGGRLGVAVLDTATGRLR-GWRGDERFPMCSTFKFLLAAAVLKSVD +QGKDRLDRRIPVTKADLLPYAPFSETRLTGTPTLAELCEAAVTLSDNTAANLLLPGVGDP +AGLTAFLRGIGDQTTRLDRNEPTLNSAIPGDPRDTTTPAAMVRGMERLLIGDVLRLDSRW +RLVDWLIANKTGDKRLRAGLPAGWRVGDKTGTGANGTANDIAIVWPDGRAPVLIASYLTQ +TAKGFKAQDSIHAEVARTVA--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. juglandis TaxID=195709 RepID=A0A383T1L5_XANCJ +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI00094ABD5A +--TVNHSFAKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS +--IEDLDQRIVYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLRAIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKMVLD-- +>[subseq from] Beta-lactamase TEM, Beta-lactamase PSE-4 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0003D6D8A2 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0009AC787D +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKDLTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKI2_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPASWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2S1T3P4_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +ADDEQLERKIHYRQQDLVDYSPVSEKYLADGMTVGELCAAAITMSDNSAANLLLATVGGP +VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=A0A0K9YPT7_9BACL +--TLDQQFKQLEKDFDARLGVYALETGTGMTI-RYRDDERFAYASTFKALAVGAVLVQSP +--TEELDKRITYTSNDLISHSPITKEHVENGMTIRELCDAAVRYSDNTAANLLLKELGGP +EGFAKVLKQIGDDVTNPVRMELELNEATPGDIRDTSTPKALANSLQAFTLGEVLPADKRF +ILTNWMKENTTGDELIRAGAPTGWVVGDKTGAGSFGTRNDIAVVWPPDRAPIVIAILSSR +DTKDAKANDALIAKAAKIVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1A9PUF6_9BACI +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVYPGDAHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIALD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKH9_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTALLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0006526185 +-dDIQRRLAALEKRTGGRLGVSVLDTETSISF-GYRGSGAFPMCSTFKALAAGFVLARAD +KGEESLDRRVTYGKDKLVDYSPISEKHAGADMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPEAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +AAAPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus sp. SDF0063 TaxID=2133753 RepID=A0A544UXQ4_9BACI +---MDIKFAALEKQFGARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP +--LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP +KGFESALRQIGDGVTKSERYETELNEAKPEDLRDTSTPKALATSLRAYTVGNALSSDKQK +ILIEWLQGNTTGAKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR +DKQDATYDDALIAEATKIVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthobacter sp. SG518 TaxID=2587119 RepID=UPI0014478E8D +---LEQAFAALEAESGGRLGVAVL-TATGASA-GYRADERFPLCSTFKALAAAAILARVD +AGTEQLERRIPVAQADILSYAPVAKQHVGGEMTIADLCAAAVLVSDNTAANLLLEALGGP +AALTAFVRTLGDTSTRLDRVEPELNEATPGDPRDTTTPAAMARDMLVLSAGTALSTASRE +RLNGWLIACTTGTAKLRAGLPADWRAGDKTGSGSHGTSNDVAVIWPPGRPPLVIASYLTQ +APGDDARRNGIHASVARAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00141B75F7 +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RCI6_9BACT +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. GV060 TaxID=2135696 RepID=A0A4R1V2B4_9BURK +--AIRARLEEIEAQSGGRLGVSIVDTTSGLHA-GLHADERFPMCSTFKLLAAGAILARVD +GGEEDLQRRIVYPESELVPYSPATSKHTRERMSIAELCKAAITLSDNTAANLLLQSFGGP +AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNMRELLLGERLKSSSRV +QLLAWLAGNETGGARLRAKLPKDWGVGDKTGTGDHGTANDVAIFWPPGRGPILVAVYLTG +TAGDAARNNAAIANVGALVVE-- +>[subseq from] Beta-lactamase CTX-M-1 n=1 Tax=Methylobacterium bullatum TaxID=570505 RepID=A0A679JZ07_9RHIZ +-rDLADRFARIEEASGGRLGIGLLDTGSGAHA-AHRGDERFPLCSTFKVLAAGAALARVD +RGEDGLDRRLRYELREVVPYSPVSGPRAGGEMTIAELCEAAVTLSDNTAANLLLGTMGGP +AGLTGHIRRFGDATTRLDRTEPDLNEAAPGDPRDTTTPRAMAETLRRLVLADALSPASRA +LLTAWLVGCRTGDARLRAGLPKDWRIGDKTGSGENDTANDVAVIWPPRRPPLVLTGYLTG +ARTSSEARSATIASVARAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. Root219 TaxID=1736493 RepID=A0A0Q8T3N0_9BURK +----LADLKRIEASVGGRVGVAALDTHTGRQI-AHRGGERFPMASTFKLLLAAQTLRRVD +QGHDKLDRRVTYAKKDLVTYSPVTEPHADGALTVEELCAGTMTLSDNTAANLLLASNGGP +PALTAYVRSLGDSITRLDRIEPELNEAKPGDPRDTTTPVAMVHCIQALALGQALSPASRE +KLQGWLLANKTGDKRLRARLPEGWKAGEKTGTASRSTSNDAGVFWPPARKPIVVSCYLTG +GEAPPEQRDAAMAEIGALVAQ-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RGT5_9BACT +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Aureimonas ureilytica TaxID=401562 RepID=UPI00036ED242 +----DAVLAGIERRFSGRLGVYVIDTATERRW-GRRADERFPMCSTFKLMAAAGLLSRVD +AGTESLSRRVVIQPTDIVTYSPVTEHRVGGEMTLAEICEAALTQSDNTAGNVLIDALGGP +AGVTDFARSIDDDTFRLDRRETELNEARPGDPRDTTTPAAMAKSLAALVQEDALSDASRH +QLVEWLVANRTGDAKLRAGLPKTWRIGDKTGGGAFGTMNDVAVIWPEHRPPIVASIYLTE +TQASFDDRNAGFAEIGHALAD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RQ38_9BACT +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=4 Tax=Bacteria TaxID=2 RepID=A0A141RGV8_9BACT +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKE5_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIYYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Oxalobacteraceae bacterium TaxID=1871070 RepID=A0A4V1TL22_9BURK +---LRAQWAEIERSSGGRLGISLLDSGTGKRI-GLREDERFPLCSTFKFVLAAAVLQRVD +KGELTLAQRVKIRAADMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP +AGLTAFLRGIGDARTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNVLKPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGTDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAAVKAVAQAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia cyriacigeorgica (strain GUH-2) TaxID=1127134 RepID=H6R1V0_NOCCG +-----PRFAELETTSGARLGVFAVDTGSGRTV-AHRADERFPMASTFKGLACGALLREHP +LSTGYFDQVIHYSAAELVEYSPVTETRVETGMTVRELCDAAITVSDNTAGNQLLKLLGGP +EGFTASLRSLGDATSRLDRWETDLNTAIPGDERDTTTPAALAADYRALVVGDVLGAPERD +QLKAWLVANTTGATRIRAGLPADWTVGDKTGSPAYGSALDVAVAWPPGRAPIVIAVLSTK +SEQDAEPDNALLAEATRVVVD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000A02BC62 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQKI-SYRPNERFAFASTYKALAAGVLLQQYS +--TENLNDVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRYSDNTAGNILFHQIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPVHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1C3PVY4_KLEPN +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRALLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. WSM2230 TaxID=944435 RepID=UPI000401624A +--AIRARLTEIESQSGGRLGVSIIDTTSGLQA-GLHADERFPMCSTFKLLAAGAILARVD +RGEENLQRRIVYSQSELVPNSPATSMHTRERMSIAALCEAAITLSDNTAANLLLQTFGGP +AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELVMGERLTSASRA +QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVAVYLTE +TAGNTARSNAAIADVGALVVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I2U9_KLEPN +-----EQIKLSESRLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTASLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea vagans TaxID=470934 RepID=UPI00077A2976 +--TLKRQFETLENKSGGRLGVTVVDTSDGSEY-SWRGNERFPLCSTSKVMAVAAILKKNE +SDHSLLDKKIHINKSDMVNYNPITQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP +QQATHFARTIGDKAFRLDRKEPELNTAIPDDVRDTTTPSAMADTLNKLVLGTALKGEQRA +KLSEWMKGNTTGANSIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKDQAPIILTTYFTQ +KDKDAVARKDVLASAAKLVMD-- +>[subseq from] Mutant KPC family beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A6B7HYP7_ENTCL +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCY-GTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000F51A251 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRSVVIYTTG +SQATMDERNRQIAGIG------- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520E9B3_9BURK +--NLVARLRQIETASGGRLGVCILNTADGQRF-GLRADERFPMCSTFKLLAAALVLQRVD +SQQDTLDRRIAIERSAIVPHSPLTEPQVGRSMTLGALCEATITQSDNAAANLMLASFGGP +AGLTAYVRSLGDPLTRLDRNEPGLNEAIAGDPRDTTTPAAMLGLMQQLVLGDALAPASRA +QLSDWLVANKTGDRKIRAGLPAGWKVGDKTGGGAFGTNNDVAIVWPPGRPPMLVTVYLTQ +TPATLAQRDATLAAVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHX7_KLEPN +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPANMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAVIGAALIEHw +>[subseq from] Class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=A0A2S7AH87_9XANT +---LRAQWAQIERGSGGRLGISLLDSATGKRI-GQREDERFPMCSTFKFVLAAAVFQRVD +QGRLTLAQQVKIRAADMVSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRYVEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDACLRAGLPRGWKIGDKTGNNGTDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDATLKAVAAAVRDSf +>[subseq from] Beta-lactamase AST-1 n=1 Tax=Nocardia asteroides TaxID=1824 RepID=BLAC_NOCAS +-----PRFAELETTSGARLGVFAVDTGSGRTV-AHRADERFPMASTFKGLACGALLREHP +LSTGYFDQVIHYSAAELVEYSPVTETRVETGMTVRELCDAAITVSDNTAGNQLLKLLGGP +EGFTASLRSLGDATSRLDRWETDLNTAIPGDERDTTTPAALAADYRALVVGDVLGAPERD +QLKAWLVANTTGATRIRAGLPADWTVGDKTGSPAYGSALDVAVAWPPGRAPIVIAVLSTK +SEQDAEPDNALLAEATRVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEF0512 +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLVQRVEIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A1T2PIB0_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTDTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTF3_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSPRLSVRSQR +QLLQWMVDDGVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. YR750 TaxID=1884384 RepID=A0A1H7Q5E8_9BURK +--SAEAQLAELERTSGSRLGVVGFNTGSGARV-QHRPHERFPLCSTFKLMLAAAVLERST +KDGSLLSRNLSYGKSDLIDHSPITEKHVATGMTVAAMCAATIQYSDNAAANLLLKELGGP +AAVTAFARGIGDQVFRLDRMEPELNTSIPGDPRDTTTPAAMSDSLQRLVLGDALGAAQRD +QLKTWLLGNTTNTDRFLSGVPAGWKVGDKTGAGSYGTTNDVGVLWPPAGAPIVLSVYLTF +PRKDAKGRNDVVASATRIAA--- +>[subseq from] Beta-lactamase n=2 Tax=Thalassospira xiamenensis TaxID=220697 RepID=A0A0B4XWW8_9PROT +--RLLDAIHTVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAVLHKVD +RESEMLDRRITYRSDDLVTYSPITEKHVDSGMTIGELCEAALHLSDNTAANLVLDVLGGP +DVLTAYLREIGDDVTRLDRIEPDLNAATPGDARDTTTPNAMRATLTYLLFGDALSLESRQ +LLEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPERKPVIAAIYITQ +TSASMGERNAAIADLGQEIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCC9D6 +-dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +KGDESLDRRITYGKDKLVTYSPETEKHAGGDMTMAEICKAAITLSDNTAGNLMLESFGGP +AALTDWLRSIGDGTTRLDRTETALNEATKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN +QLIDWMIANTTGGARLRAGLPSDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYIGE +ATVKMDEFNPVFAEIGKMITE-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. 78 TaxID=2135631 RepID=A0A2U0SU20_9BURK +--AAHTQLAALEQAAGGRLGVAAWRHGSELRV-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLDQHVRYDKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGDVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLVIAVYYTR +EQKKADTNQDIITAATRIVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0003603C0C +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLILGSVLTEASSG +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium phaseoli TaxID=396 RepID=UPI0007EAE84D +--NVERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD +KGDESLDRRVTYGKEKLVDYSPISEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +KLIAWLVASTTGKERLRAGLLADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATTPAKDLNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF30303 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYKKKDLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +NGYEKALRQLGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAQKSK +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=A0A4V2TJC8_RAOOR +heATVKQVKAAERLLEARVGYVELDIASGRLLaSYRPGERFPMMSTFKVPLCAAVLARVD +AGEEQLDRRVRYRQQDLVEYSPVTEKHLADGMTVAGLCAAAITLSDNTAANLLLASVGGP +QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLSGSVLSAASRQ +QLRNWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMEERNRQIAEIGEMLVKHw +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus fortis TaxID=2126352 RepID=A0A2P7UWB7_9BACL +--QIDQKFADLEKKFEARLGVYAIDTNTNQVV-AFRSDERFAFASTFKALVVGALLHQKS +--LDELDKVIKYTSSDLVTYSPITEKHVSTGMTLREISDAAIRYSDNTAGNLLFKELGGP +KGFEAALRKIGDQVTTSERNEPELNEAIPGDIRDTSTPKALATSLMAYTVGDVLTEDKQK +ILNDWLQRNTTGDKLIRAGLPKEWKVGDKTGAASYGTRNDIAVIWPPDKKPIVLAVLSSR +DTKDATYDNALIAEATKLVMD-- +>[subseq from] BBI family class A beta-lactamase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI00085379B7 +--AMDQKFAALENKFDVRLGVYAIDTETDVVV-AYREDERFAFASTYKALAAGAVLHQKP +--LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP +KGFESALRQIGDSVTTSERYEPELNEAKPEDIRDTSTPKALATSLRAYTVGDVMSSDKQT +ILIEWLKGNTTGDKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR +DKQDATYDDALIAEATKVAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL10I2N1 TaxID=1938796 RepID=A0A4R6F7M3_9BURK +--STEAQLATLEKSSGGRLGLFALNTATGEQT-RYRADERFPFCSTFKVILAGAILTRST +RVPGFMQQCVNYAQSELVHYSPVTAEHVGDGMTVAELCRAAIQYSDNTSANLLMKMLGGP +AAVTSFARSIGNSEFRLDRWETELNSVVPGDQRDTSTPAAMARSLQTLALGDTLPPPQRA +QLLDWLRGNKMGAKRIGAAVPADWQIGDKTGTGDYGTANDIAVLWPPAREPVVLAIYHTQ +LAADAKSRDDVIAVAARIVVN-- +>[subseq from] Beta-lactamase n=1 Tax=Herminiimonas fonticola TaxID=303380 RepID=A0A4R6G6W2_9BURK +--AANNELEKLEASANGRLGVAAINTGNGMRV-QYRADERFPFCSTFKTIVAAAILQKSA +TDKGLLAKRIHYNKDELVKYAPITQKYIADGMTIAELCAATLQYSDNAAANFLMKELGGP +AAVTAYARSIGDDTFRLDRWEPELNSAIPCDERDTTTSAAMEKSLQQLMLGDALAVSQRV +QLVAWLKGNTTGGKRMLAGVPKDWIVGDKTGTGSYGTTNDAGVLWPVNGAPIVAVVYFTQ +NDKTAAPRDDVIAAATRIVIAAf +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000D749FF8 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola pv. populi TaxID=487823 RepID=A0A2S7B4U3_9XANT +---LRAQWAEIERSSGGRLGISLLDSGTGKRI-GLREDERFPLCSTFKFVLAAAVLQRVD +KGELTLAQRVKIRAADMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP +AGLTAFLRGIGDARTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNLLKPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGTDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAAVKAVAQAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. C16 TaxID=2487400 RepID=A0A3S0Q2K0_9RHIZ +-dNVEKRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGEEKLDRRVTYGRDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVKDLNPIFAEVGKMIVE-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-36 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2Z5FPM1_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLERWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0009B570D5 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVRGSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RFN3_9BACT +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL83_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTXGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAXXTTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKH- +>[subseq from] Beta-lactamase (Fragment) n=5 Tax=Gammaproteobacteria TaxID=1236 RepID=G9G8D3_PSEAI +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPSDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. IBUN TaxID=1042326 RepID=UPI000413B245 +-dEINRRMDALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP +AELTKWLRTLGDRSTRLDRWETALNVAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD +KLVAWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYVTQ +AKAPVSEINPVFAEVGKIVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=J8FCR9_BACMY +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLDYf +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEED68F +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQQVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] class A beta-lactamase LEN-31 n=1 Tax=Klebsiella TaxID=570 RepID=UPI00032DDE2A +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTHLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] OFF7_DB12V4 n=1 Tax=synthetic construct TaxID=32630 RepID=UPI00077DEFAD +----AAKVKDAADQLGARVGYIELDLNSGKILaSFRSEERFPMMSTFKVLLAGAILSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELASAAITMSDNTAANLLLTTIGGP +KGLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTPASRQ +QLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIVAALGPDGKPSRIVVIYTTG +SQATMDELNRQIAEIGASLIKGw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3P4IN76_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVSGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus ATCC 4342 TaxID=526977 RepID=C2QT98_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKDLTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=3 Tax=Xanthomonas arboricola TaxID=56448 RepID=A0A2N7V2J1_XANCJ +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKE8_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHCSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=UPI0011E934EE +----AHKFMQLEKKFDARLGVYAIDTGTNRTV-VYRPDERFAYSSTFKALAAGAVLQQNS +--IEELDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLEEIGGP +DGFENALRQIGDHVTEADRFETDLNSAIPGDIRDTSTARALAINLKAFTVDDVLPIDKRT +ILTDWMKGNTTGDELIRASVPKGWEAGDKTGAGGYGTRNDIAIVWPPNRDPIIITILSSR +DTENATYHNELIAKAAKVVLNSf +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora globbae TaxID=1894969 RepID=A0A420F021_9ACTN +------DFGRLEARFDARLGVYAVDTGTGRTI-EHRADERFGYASTFKALAAGALLAATS +--TTELDRVVRYTEADLVTHSPVTERHVKTGMTLRELGDAAVRYSDNTAANLLLRRLGGP +AGFERALRELGDRVTDPERFETDLNEATPGDRRDTSTPRALASDLRAYILGDALAPEDRA +VLTGWLKGNTTGDTLIRAGVPAGWQVGDKTGSGGYGTRNDIAVVWPPDGAPIVLAILSSR +EEKDASSDDTLIAEAAKATIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000B451C70 +--TVNHSFAKLEKEFEAKLGIYALDTDTNQTV-KYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDILSTEKRN +LLIDWMKRNTTGDKLIRAGVPGDWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDF554D +--QFRPALEAIETRIQARLGAFVLDTETGTTL-GYRADERFPMCSTFKAIAAAAVLSRVD +AGKEDLSRRLHWKKADLIAHSPVTEKHVEAGLTLAELCHAATTVSDNTAANLLLEAIGGP +AGFTAFVRSVGDPVTRIDRMEPALNSAKPGDTRDTTSPSAMAALLKSLVLDDALSPASRD +QLGQWMIANTTGGSKLRAGLPRGFIVGDRTGAGANGTNNVVAVIWPPERKPLVATVFITE +TRTPRPETDPAMAEIGRL----- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKF1_9BACT +--ETLVKVRDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGPRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00102F5E76 +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFALARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDATTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. 3376 TaxID=2663862 RepID=UPI00142F4D06 +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP +PGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] class A beta-lactamase LEN-55 n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000BA1327B +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D618_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000E2BD875 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] OFF7_DB08V4 n=1 Tax=synthetic construct TaxID=32630 RepID=UPI00077DEFBE +------QVAAAADQLGARVGYIELDLNSGKILeSFRSEERFPMMSTFKVLLAGAILSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELASAAITMSDNTAANLLLTTIGGP +KGLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTPASRQ +QLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIVAALGPDGKPSRIVVIYTTG +SQATMDELNRQIAEIGASLIKNw +>[subseq from] Beta-lactamase n=2 Tax=Paenibacillus mucilaginosus TaxID=61624 RepID=I0BH80_9BACL +--SAKQPFARLESEYKARLGVYAVDTGTGRTI-EFRPDERFAYASTFKALACGAVLKAKP +--LEGLEDRVTYTSGELVTYSPVTEKHVSTGMTLRELCDAAIRYSDNTAGNLLLKQLGGP +KGFEAALKEAGDAVTKAERYETELNEAVPGDDRDTSTPRALASSLRAFTLGDALSADKRD +VLADWLRRNTTGGELIRAAVPEGWVVGDKTGAGSYGTRNDIAVIWPPDGPPIVMAVLSSR +DTKDAAYDNALIAKAAKAALD-- +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter farmeri TaxID=67824 RepID=A0A223JSU2_9ENTR +--QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRADERFAMCSTSKTIVVAAVLKQSE +TQHDILQQKMTIKKTDLTNWNPVTEKQVNKEMTLAELSAATLQYSDNTAMNKLLEHLGGT +GNVTAFARSIGDATFRLDRTEPELNTAIPGDERDTTSPLAMAKSLHKLTLGNALADMQRA +QLVAWLKGNTTGGQSIRAGLPESWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ +PQQDAKGRKDILAAAAKIVTE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEFCD86 +--AMYKNFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEVTYDNQLIAEAAEVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKH6_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGVTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00141BF4B5 +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQLASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGTDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Inhibitor-resistant carbapenem-hydrolyzing class A beta-lactamase KPC-51 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A650DI28_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARNTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGHGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKNSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas azotifigens TaxID=291995 RepID=UPI0004265009 +--AFERRLARIEAEVCGRLGVALLDTDDGLRA-GRRQDERFPLCSTFKFLAAAALLARQD +RGELSLAQRVVFGEADLVEYSPVTGARTGGEMTLAEICEAAVTRSDNTAGNLMLAHLGGP +QGLTAFARGLGDRQTRLDRLETELNEALPGDPRDTTTPAAMLADMRELLLGTHLSPASRE +QLQAWLIANRTGDARLRAGVPKDWRAGDKTGSGERGTANDIAIFWPPTRGPVLVAVYLTG +SAADMDRRNAAIVQVGTALAE-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000859D685 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMGDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1C4DFF5_BACCE +--TVNHPFSKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFGLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A242ZFI8_9BACI +--TVNHPFSKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFGLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Labrenzia sp. THAF187b TaxID=2587864 RepID=A0A5P9BXV5_9RHOB +---LEKTVAGAESRLSARIGVAVLDTETGKTW-TYRADERFPLNSTFKAFLCAALLEKGE +QGEVQLERRVKIRSQDLVSYSPVTEKKVGSGMTYLELCEAAVAISDNAAANLVLEAVGGP +EGLTDYLRGIGDTITRLDRTEPGLNEGRPGDARDTTTPAAAVATLQKLVLGDALSSTARA +QLTGWLLDNKVGNATLRAGLPEEWPVADKTGAGANGSRNNIGVIWPDDREPVVIAVYITQ +TDASFDDRNKAIADIAAALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter sp. 10-1 TaxID=559104 RepID=A0A267RL20_9ENTR +hdATVNKVKAAESQLKARVGYAELDLASGQLLaSYRPDERFPMMSTFKVPLCAAVLARVD +AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAELCAAAITLSDNSAANLLLASVGGP +EGLTAFLRRSGDQTSRLDRLETELNEALPGDARDTTTPQAMAKTLRNLLTGSVLSASSRQ +QLRRWMVDDKVAGPLLRSALPNGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMEERNREIAGIGETLIKHw +>[subseq from] Beta-lactamase n=3 Tax=Xanthomonas arboricola pv. pruni TaxID=69929 RepID=W4SHG2_9XANT +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIHNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0B5A120_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter agglomerans TaxID=549 RepID=UPI000C06EE12 +-qTLKSQFETLESKSGGRLGVTVVDTSDGSEY-SWRGNERFPLCSTSKVMAVAAILKKNE +SDHSLLDKKIHINKSDMVNYNPITQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP +QQATQFARTIGDKAFRLDRKEPELNTAIPDDVRDTTTPSAMADTLNKLVLGTALKGEQRA +KLSEWMKGNTTGANSIKAGLPVDWIVADKTGSGDYGTTNDIAIIWPKNQAPIILTAYFTQ +NDKDAVARKDVLASAAKLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C0XTV2_BACCE +--TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNRKPIVLAILSNH +DKEDAKSDDKLIAEATQIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchialis TaxID=463025 RepID=UPI0009F6432D +------EYAALEQSHRRRLGVYALDTGSGQEV-AYRAGERFAFCSTFKAILAAAVLAQDA +GKPGLLRQRVAYTKSDLVSYSPVTGEHAGAGMTIAELCAAAVQYSDNTAANLLLHRLGGP +AALTAFARQAGNPSFRMDRYETALNTAIPGDERDTSTPADMAGLLRALVLGDALPAPARA +QLKTWLLGNKTGAHRIRAAVPGGWAVGDKTGTGDYGSANDVGIIWPPSRPPIVMAIYTGS +RDKRAKADEGLIAEAARIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus glycinifermentans TaxID=1664069 RepID=UPI000653CAC5 +----SNQFSRLEDQYDARLGVFALDTGTNKTV-TYRADERFAYASTHKALAVGALLKQTS +--IADLNQRITYTRDDLVNYNPITEKHVDTGMTLKELCDASIRYSDNTAGNLILKQIGGP +SGFKQSLREIGDNVTNPERIEPDLNEVKPGETHDTSTPKALAKSLQAFTVGDALPKEKRE +MLVDWLKRNTTGDALIRVGVPKGWEVADKTGAGSYGTRNDIAVIWPSKGDPIVLAVLSSR +DKKDADYNDKLIAEAAKEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Bk TaxID=1938441 RepID=UPI000B48E883 +--TIRARLREIEADSGGRLGVAIVDTTSGLHA-GLHADERFPMCSTFKLLVAGAILARVD +RGEEDLQRRIVYSQSELVPNSPATSKHTRERMSVGDLCKAAITLSDNTAANLLLASFGGP +AALTAFARSLGDGITRLDRIEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA +QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIVWPPGRGPILVAVYLTE +TAGDAVRCNAAIASVGALVAQ-- +>[subseq from] Class A beta-lactamase TEL-1 n=2 Tax=unclassified Citrobacter TaxID=2644389 RepID=A0A650EM83_9ENTR +--QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTIVVAAVLKQSE +TQRDILQQKMAINKADLTNWNPVTEKYVDKEMTLAELSAAALQYSDNTAMNKLLEHLGGT +GNVTAFARSIGDTTFRLDRTEPELNTAIPSDERDTTSPLAMAKSLHKLTLGDALAGMQRA +QLVAWLKGNTTGGQSIRAGLPESWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ +PQQDAKGRKDVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia hospita TaxID=169430 RepID=UPI000271AE47 +--ALEKQLAQIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD +QGKEQLERKIVYSKDVVVANSPVSGPRAGGDMTVAELCEAAITRSDNTAANLLLDSIGGP +AALTAFARGIGDRITRLDRKEPTLNEALEADPRDTTTPAAMLADMRALLLGEHLSAASRE +QLTAWLAGNKTGDARLRAGLPKAWRVGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG +ATATSTQRDAAIAQVGALVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Legionella taurinensis TaxID=70611 RepID=A0A3A5L4J6_9GAMM +--SLQQKLAALEASAGGRLGIAAINQANGMTI-QYHARQAFPLCSTSKAMSVAALLSQNM +RNKTLLQEKIHYSKQDLVVHSPETEKHLADGMTLAELCEATITQSDNAALNLILKKIGGP +GAVTAFARSIGDKQFRLDRFEPDLNTAIPGDPRDTTTPKAMALSLQKLTTD-TLAAPERQ +LLITWLRNNTTGGARIRAGLPEGWVVGDKTGTGDYGTSNDIGVIWPPHCQPVTLAVYFTQ +PKVDATPNNDVIAAATRIVISAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI000374CAD5 +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSETFPMCSTFKALAAAFVLARAD +KGEENIDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLKEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus var. anthracis (strain CI) TaxID=637380 RepID=D8GY68_BACAI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLVEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Haliea sp. TaxID=1932666 RepID=A0A519HD37_9GAMM +--AAQARLAALETASGGRLGVFALNTADGSVI-SHRGDERFPLCSTFKAIAAAAILERNM +REPGLLSQRIKYTQVELVTYSPITEKHLADGMTVAELCAAAIQYSDNTAGNMLIKVLGGP +PAVTAFTRSIGDNAFRLDRWETELNTAIPGDARDTTTPAAMAATLQKLVLGDTLAPPQRE +QLQAWLRGNTTGATRIRAGVPAGWIVGDKTGGGDYGANNDVAVLWPPGKPPIVLALYMTQ +----------------------- +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=UPI000F297080 +heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRAD +TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ +QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA +TPASMDERNKQIATIGETLVRHw +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1D9N9L5_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQ-IAGIGAALIEHw +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000D75085B +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D617_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5C2D365_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSTIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGAANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000C85B9E2 +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +MGELTLAQRVKIHASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDTHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3R967_9BURK +--AAHDALRQLESDMGGRLGVAAFDGRPGSLAlLHRADERFPMCSTFKVIAAAGVLARSA +REPGLLNQRTRYTREDLVTYSPVTEKHVADGMTVAELCAAALQYSDNTAGNLLIRLLDGP +AGVTRYARSIGDEGFRLDRWETELNTALPGDPRDSTTPASMARSLQRLLLQNGLPAAQRA +QLEQWMRGNTTGATRIQAGVPAGWAVADKTGAGAWGTTNDVGVVWRADGSPLVLAIYLAQ +PRADAPMRNDTVAAAARIAAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus hauseri ZMd44 TaxID=1312367 RepID=V6MJL4_PROHU +-nTIEEQLSTLEKYGKGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE +KQAGLLDKNITIKKSDLVVYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP +AKVTQFARSINDVTYRLDRKEPELNTALHGDPRDTTSPIAMAKSLQALTLGDALGLSQRQ +QLVTWLQGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEKDAKYRKDIIAKAAEIVTKPf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI0004C542C7 +--EVSRRLQALESEHGARLGVFARNLDTGETV-VRRADERFPMCSLFKPVAAAAILRDHD +RNGAFLARRIRYSETDLVTHSPITKDHVAEGMTVGELCDAAIRFSDNTAANLLLRELGGP +RAVTRFCRSVGDRTTRLDRWEPELNTAEPWRVEDTTSPRAIARTYTRITIGDALSPADRE +RLTGWMLANTTSGERFRAGLPAAWDLADKTGGGDYGTNNDAGVAWTPDRTPIVLAVLTTK +PAPDAAPDNALIAETAELLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000C8306A1 +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTSTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase n=1 Tax=Lysobacter enzymogenes TaxID=69 RepID=A0A1H2RD10_LYSEN +--ALRARLAELEKRSGGRLGVSALDTADGRRF-DVRGDERFAMCSTFKFLLAAAVLRKAD +LGELDMQQRLAVPKSALISHSPITTPIAEAGASLAQLCEATMTISDNAAANLLLPLVGNP +AGLTRFLRGIGDKVTRLDRNEPELNTALPGDPRDTTSPNAMLASMRTLLLGDALSAASRR +QLTDWLIANQTGDKRLRAGLPKSWRIGDKTGSGN-GTTNDIAIIWPQGRKPVFITTYLTQ +AQGEDDARSAILADAARALAQHw +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia nodosa TaxID=392320 RepID=UPI0008414357 +--AVEKQLAAIEAQAGGRLGVAMLDTANGHVR-GWRMHERFPMCSTFKVLLASAVLTRKD +HGKEDLARKIVYSLAQVVSYSPVSGPRAGSEMTVAELCEAALTRSDNTAANLLLESIGGP +PAITAFARSIGDPVTRLDRNETTLNEAIPGDPRDTTMPAAMVANLRELLLGERLSAASRE +QLIAWLVANKTGDARLRAGLPKDWRVGDKTGTGDHGTANDVAIVWPTERAPILVTTYLTG +ATASSAQRDAAIAQVGVWA---- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AEAE2A +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLVEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. EL159 TaxID=1566270 RepID=A0A1G4XX81_9BURK +--SAEAQLAALESASGGRLGVVAFNTASGARV-QHRAHERFPFCSTFKLMLSAAILERSA +KDASLFTRRVNYSKGDLVSYSPVTEKNLATGMTVAELCAATAQYSDNGAANLLLKILGGP +PALTAFARSIGDQTFRLDRWETELNTAIPGDLRDTTTPAAMADSVQRLVLGDALGSAQRE +QLRTWLLGNTTSKERFLAGVPADWKVGDKTGSGDYGTTNDIGVLWPPAGAPLVVTVYLTF +PQKDAKGRNDVVASATRIVAT-- +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. 35 TaxID=2035210 RepID=UPI000C181BE8 +--AAHTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLDQHVRYDKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGDVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLVIAVYYTR +EQKKADTNQDIITAATRIVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C2F9K3_BACCE +--TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPKRFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPVVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Gibbsiella quercinecans TaxID=929813 RepID=A0A250B928_9ENTR +hqATLDKVKEAEGLLNARVGYAELDLTSGNLLeSYRPQEHFPMMSTFKVLLCGAVLSRVD +SGHEQLDRRIQYHQRDLVEHSPVTEQHLSDGMTVAELCRAAITMSDNTAANLLLSTIGGP +RELTAFLRKTGDKVTRLDRWEPELNEALPGDERDTTTPKVMAQTLRQLLTGKTLTATSQK +QLMDWMEADKVAGPLLRSVLPAGWFIADKTGAGERGSRGIVAALGPDGKPSRIVVIYLTG +TQATMDERNKQIAEIGELLIKYw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sullae TaxID=50338 RepID=A0A4R3QLS6_RHISU +-dDIERRLAELEKRTGGRLGVSVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD +KGEENLERRVIYDESKLVSYSPETEKHVGGEMSVAELCKAAITLSDNTAGNLLLESFGGP +EALTKWLRSIGDRSTRLDRWETALNEGKKDDPRDTTTPDAMLDTLGNVALGSVLSEPSRN +TLIGWMMANTTGGARLRAGLPGSWKVGDKTGTGNNGTAADIAITWPKGRGPILVTTYIAE +ATAPVKELNPVFAEVAKIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Yersinia pekkanenii TaxID=1288385 RepID=A0A0T9NHX1_9GAMM +--SLDNQLAELEQTSNGRLGIALINTANGKKV-QYRGGQRFPFCSTFKLMLAATVLGHSQ +FQPNLLNKHLRYHENDLLSYAPITRKNLAQGMTISQLCAATLQYSDNTAANLLIKELGGL +GSVNQFARSIGDQTFRLDRWEPDLNSALPNDPRDTTTPVAMAASLQKLVLGDALAAPQRE +QLARWLKGNTTGGETIRAGAPADWVVGDKTGSGDYGTTNDVAVLWPTQGAPLVLVIYFTQ +RNKEATSRRDVLASATKIVLSH- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 17-SMS-01 TaxID=2039284 RepID=A0A2G6Q9Z8_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTSTNQTI-SYRPNERFAFASTYKALVAGVLLQQNS +--TEKLNEVITYTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +NGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVQKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVVVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Glaciimonas immobilis TaxID=728004 RepID=UPI0014399D3D +---AKNKIEKIERDFDGRLGVSVRDTATGRQL-GHRADERFPFCSTFKVIAASAILTKSV +QVPGLMERVIRFRQSDLVTYSPVTEKHVDTGMTVADLCAAGIQYSDNTAANLMIKLIGGP +AAVSAYARTIGDTAFRLDRWETALNTAIPGDLRDTSTPFAMCQSLNRLLLGDAMSFAHRE +QLRSWLSGNTTGAQRIKAGIPGDWLIGDKTGSGDYGTANDLAVLWPPKRAPVIVAIYTTQ +HAKEIASRSDIIASATRVVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhizobium TaxID=2613769 RepID=UPI00056A589C +-dEINRRIGALEKAIGGRIGVSAIDTQTNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQETLERRVVYDQDKLVTYSPETEKHVGGEMSLSELCEAAITLSDNTAGNLLLESFGGP +PELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLALGSALSEPSRD +KLTEWMVANTTGGARLRAGLPGAWRIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYVTQ +AKAPLSEINPVFAEVGRIVAD-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus cereus group TaxID=86661 RepID=A0A0J7DJ89_BACCE +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIALD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B5NL20_9BACI +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIALD-- +>[subseq from] Beta-lactamase KPC-15 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=M1NGU8_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVRWSPISEKYLTTGMTVLELSAAAVQYSDNAAANLLLKELGGP +AKLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] BBI family class A beta-lactamase n=1 Tax=Brevibacillus porteri TaxID=2126350 RepID=UPI000D10A78E +--AMDQKFAALETKFDARLGVYAIDTETDVVV-AYREDERFAFASTYKALAAGAVLHQKP +--LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP +KGFESALRQIGDSVTTSERYETELNEAKPEDIRDTSTPKALATNLRAYTVGDVLSSDKQT +ILIEWLKGNTTGDKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR +DKQDATYDDTLIAEATKVAVE-- +>[subseq from] Beta-lactamase n=3 Tax=Klebsiella TaxID=570 RepID=Q939H3_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A1L3ZAF3_RHILE +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSESFPMCSTFKALAAAFVLARAD +KGEENLDRPVSYGEDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPVDWTVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0012989DAC +-qATHKEFSQLEKKFDARLGVYAINTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] class A broad-spectrum beta-lactamase OKP-B-22 n=1 Tax=Klebsiella TaxID=570 RepID=UPI000F01C784 +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMTERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. glycines TaxID=473421 RepID=A0A517GRB7_XANCG +---LRAQWAEIERRTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMVYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLADWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDATLKAVAAAVRD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=UPI00028A58B2 +--QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAD +RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP +PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQPASRQ +RLAGWLLASQTGDTRLRAGLPAGWRIGDKTGVGGHGTNNDIGVIWPRDGAPALISAYLTQ +SSASREAQNAVLAEVGRIAAH-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007E8FA21 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVXLCGAVLARXD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATXGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLXSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus hwajinpoensis TaxID=208199 RepID=UPI0013705C2B +---TGRKFMQLEKKFDARLGVFAIDTSTNRTV-VYRPDERFAYTSTYKAVAAGLVLQQNS +--IDKLDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLQKLGGP +NGFEKALRQIGDNVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPNGKRA +ILTDWMRGNTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPNRDPIIIAILSTR +DTKNATYNNDLIAKTAKVALNAf +>[subseq from] Beta-lactamase n=1 Tax=Rhodovastum atsumiense TaxID=504468 RepID=A0A5M6IQK2_9PROT +----EARLAALEREHGGRLGVAVLDVATGHRI-AYRAEERFPLCSTFKVLAAALVLARVD +RGKERLDRRVVFSREDIRPWSPVTEKHPGAPMTLAELCEAAVTLSDNTAGNLLLGSFGGP +AGLTGFARALGDDVTRLDRFETALNEGTPGDPRDTTTPAAMLGNMRRIMVGDALSESSRT +QLAGWLLGSRTGGRRLRAGFPPDWRVGDKTGGNGTGVANDIAIAWPPGGGALLVAAYYAE +SPGPEERRNAVLAEVGRIAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF8C2AB +--TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPVVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium laguerreae TaxID=1076926 RepID=A0A4R0A414_9RHIZ +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARTD +KGEENLGRRVSYGRDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEE1C1A +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAASVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00020599E6 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKQKP +--IEKLNDVIRYTKEDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR +FTKDAEYDNALIAEAAKVALD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKJ5_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSAFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Class A beta-lactamase n=1 Tax=Rahnella sp. AA TaxID=2057180 RepID=A0A2N0W036_9GAMM +--TVQQQLAALEKDSGGRLGVMLINTADNSQI-AYRADERFAMCSTSKFMAASAILKQSE +TQKDLLAQPVSIKKSDLVNYNPIAEKHVNGTMTLGELAAAALQYSDNVGMNKLIEHLGGP +QKVTEYARTLGDDTFRLDRTEPTLNTAIPGDERDTSTPRAMALSLQKNALGDGLARPQQA +QLVEWMKGNTTGAMSIRAGLPATWIVGDKTGSGDYGTTNDIAVIWPENKAPLVLVTYFTQ +PQQDAKSRRDVLSSAAKIVTQGy +>[subseq from] Beta-lactamase n=1 Tax=Pragia sp. CF-458 TaxID=2498113 RepID=A0A411WK11_9GAMM +--TIQQSLADLEKSSGGRLGVVLINTADNSQI-VYRGDERFPMCSTSKMMVVAGVLKQSE +SQKGLLDQQVDIKKKDLVSHSPIAEKRLNNKMSLAELSAATLQYSDNAAMNKLIEQLGGT +KKATAFARSIGDKTFRLDRTEPTLNTAIPGDKRDTTTPLAMALSLQKLTLGDALAAPQRD +QLVEWLKGNTTGAASIRAGLPTEWVVGDKTGSGSYGTTNDIAVIWPKDKAPLILVTYFTQ +NEKEAKSRREVLASAAKIITQ-- +>[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000BBAD118 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGTNALVPWSPISEKYLPTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKC0_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELPTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium acidisoli TaxID=1538158 RepID=A0A0N1DNN0_9RHIZ +-dNIQKRLAALEKRTGGRFGVSVLDTDTSISF-NYRGSEAFPMCSTFKALAAGFVLARAD +RGEESLDRRVTYGKDKLVDYSPLSEKHADADMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSILTEASAD +RLVAWLVASTTGSERLRAGLPAGWKVGDKTGTGPNGSLGDIAVIWPPNRGPIVAAVYIAE +ATAPVKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF701F9 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNY +--TKKLDEVITYKKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +NGYEKALRQLGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAQKSK +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=A0A5C8IWN5_BACAM +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKQKP +--IEKLNDVIRYTKEDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR +FTKDAEYDNALIAEAAKVALD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus paranthracis TaxID=2026186 RepID=A0A4P9F0E4_9BACI +-qATHKEFSQLEKKFDARLGVYAINTGTKQTI-AYRPNERFAFASTYKAFAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATDLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RDQ7_9BACT +heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD +TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTPLGGP +QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ +QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA +TPASMDERNKQIAAIGETLVRHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. HBCD-sjtu TaxID=2053832 RepID=A0A2K9A302_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TMKLDKVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDWVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIVAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Aureimonas sp. AU20 TaxID=1349819 RepID=A0A0S2EK77_9RHIZ +--ALNALLADIEKRFSARLGAFVHDTGSGRRW-ARRADERFPLCSTFKVVAAGGLLAQVD +RGEADLSRRVVIAKSDLVTYSPVTEKQVGGEMTLAEICAAAITRSDNTAGNVLIDQLGGP +EGVTRFARSLGDETFRLDRRETDLNEATPGDPRDTTSPAAMTKTLHALLFEDHLKDVSRW +RLAEWMVANQTGGAKLRAGLPKSWHIGDKTGGGDHGTMNDIAVLWPPEGAPIVASLYLTE +TEASFDERNAAFAEIGNALA--- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E58AD9E +--ETLVKVKDAEDQLGARVGYIELISTAVRSFeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus TaxID=1386 RepID=UPI000B4BF51D +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYENALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKELTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIAKAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. (strain CCGE1003) TaxID=640512 RepID=E1TJ23_BURSG +--AIRARLVEIEAQSGGRLGVSIVDTTSGLHA-GLRADERFPMCSTFKLLAAGAVLARVD +RGEENLQRRIVYSQSELVPNSPATSRHTRERMSIAELCKAAITLSDNTAANLLLQSFGGP +AALTAFARSLGDGMTRLDRNEPTLNEAAPGDPRDTTTPNAMLGNLRALVMGEQLSSTSRV +QLLAWLAANETGGARIRARLPKDWGVGDKTGTGGHGTANDVAILWPPGRGPILVAVYLTG +TAGTAARCNAAIADVGALVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1L2K8_BACCE +--TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPEHFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS +LLIDWMKRNTTGDNLIRAGVPRGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces tubercidicus TaxID=47759 RepID=A0A640UR18_9ACTN +---SAREFKALERKFDARLGVYALNTGTGREV-SYNADQRFAHASTFKAMAAGAVLRKYS +--LHGMDKVIKYSRDDLVPYSPVTEKHVDTGMTLRELCDAAVRYSDNTAANLLFDALGGP +KGLDSVLEELGDHTTRMVRREPELNEWAPNDTRDTTTPRAFAKDLRTFVLGDVLPRPERA +QLTKWLQTNTTGATLIKAGVPKNWVVGDKTGAGSYGTRNDIAVVWPPHAAPIVVAILSNR +TEKDGERNDALVAQAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q5S1P8_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSVANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TLASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000BFB8C17 +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--MEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKRPIVLAILSNH +EKEDAKYDDMLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0J7CWQ7_BACCE +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--MEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKRPIVLAILSNH +EKEDAKYDDMLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD71813 +--DVEARLAELEKRTGGRLGVSVLDTATNISF-GCREDERFAMCSSFKALAAGFILARVD +QGAETLDRRIVVAQKDIIAHSPVTEKHLGGEMTIADLCAATMTTSDNAAANLLLESFGGP +SALTAWLRMIGDETTRLDRNEPTLNEAKKGDPRDTTTPAAMLETLGNLAFGPALTADSRK +RLIEWMVANTTGDKRIRAGLPKGWKVGDKTGTNATGSASDIAIVWPEGRAPLLIAVYIAE +ATAPLSVLNTVFADVGRMAAE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKC5_9BACT +----LVKANDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRFVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola subsp. tropicalensis TaxID=2489014 RepID=A0A455LP02_KLEVA +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITMSDNSAGNLLLATVGGP +VGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGNAERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI000D17DC58 +--ALARAVQEIEASVGGRLGVALLDMATGRQG-AHRGDERFPLCSTFKLVLAAHVLRRVD +QGQERLDRRITYGQSDLMEYSPATERHVDGDMTVEQLCEAAVTLSDNTAANLLLGMPGGP +LGLTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSAAARA +QMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDIGLFWPPDRGAVMVSCYLTG +SPAPAEQRDAALARVGALAA--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X1B2_9BACT +----KHHFVKLEDKFDARLGVFALDTSTNQTV-TYRADERFTYASTSKALAVGALLQQKT +--IEDLNQRITYTQDDLVNYNPITEKHVDTGMTLKELCDAALRYSDNTAMNLILKQIGGP +NGLEKALRDVGDNATMPEQFEPELNEVKPGETHDTSTPRALATSLQSFTLGDVLPIEKRE +LLIDWMKRNTTGDSLIRAGVPKGWVVADKTGSGSYGTRNDIAIIWPPKGEPIMLAILSSR +DKKDANYNDKLIAEATKEVINAy +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D626_KLEPN +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMVERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL21I4N1 TaxID=1938801 RepID=A0A2S8RZY6_9BURK +--TIRRRLARIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKVLAAGAVLTRVD +RGQESLARRIVFSQRDVVPNSPATSRHTRERMSIADLCKAAITLSDNTAANLLLSTFGGP +AGLTAFARDLGDGITRLDRIEPTLNEAIPGDPRDTSTPNAMLGNLRELVLGEHLSASSRA +QLLAWLVANETGGARIRAKLPQDWGVGDKTGTGDHGTANDIAILWPPGRGPVLVAVYLTG +TDGDAARCNAAIAQVGALVVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Desulfovibrio sp. TaxID=885 RepID=A0A3D4GKK6_9DELT +-kALQAQLAALSREAGGRLGVAFLDPATGRRF-AFRGGERFPFCSTFKFVLAAAVLRKSQ +DEPGLLAQPEAYGQGDLLAWAPATRKALEQGMTVGELCAAAITVSDNTAANLLLDRIGGP +KALTAFARGLGDTAFRLDRREPELNTAVPGDARDTTTPLAMARTMAKLVLGDALAAPQRR +QLADWLKGNTTGGESIRAGVPAGWTVGDKTGGGAYGTTNDVAVLWPPQGGPVVLAVYFTQ +PRKDALARKDVLAAATRLVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. YIM 10 TaxID=2653857 RepID=UPI0012902E9C +--AVEQEFNRLQTQHDARLGIYAVDTGSGKSI-AFRADERFAYASTFKALAAAAVLDTTT +--PQQLDEVVRYTAEDMLANSPITEQHLDTGMTLRDLCDAAVRYSDNTAGNLLLRHVGGP +AGLDAALTAIGDDVTSVDRYEPDLNSAIPGDVRDTSTPRAMAGNLRQYVLGDALAEDDRA +VLTDWLRRNTTGATLIRAGVPGDWVVGDKTGSGYYGGRNDIAVLWPPNRAPIVMAVMTSR +DEPRAKRADALLADAARVAVT-- +>[subseq from] Beta-lactamase n=1 Tax=Lysobacter enzymogenes TaxID=69 RepID=A0A3N2RKG9_LYSEN +--ALRAQLRELERRSGGRLGVSALDTGDGRRF-DVRGDERFAMCSTFKFLLSAAVLHKVD +RGDLDLQQRIAVTKSALVPHAPFTGPIAEAGASVAQLCEATMTLSDNPAANLLLPLVGNP +AGLTRFLRGIGDPTTRLDRNEPELNSAAPGDPRDTTSPNAMLASMRTLLLGDALSAASRK +QLADWLIANKTGDKRLRAGLPKDWRIGDKTGSGNT-STNDIAIVWPDGRKPVLMTVYLTQ +AQGEDEQRSVILAETARALAAHw +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella sp. H-Nf2 TaxID=2054599 RepID=UPI000C288D5E +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATIGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDMRDTTTPASMAATLRKLLTAQHLSARSQH +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKI0_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAER-------- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000BF49C3F +-qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IHTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKELTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSNK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. Root217 TaxID=1736492 RepID=A0A0Q8SBG3_9BURK +----LADLKRIEASVGGRVGVAALDTHTGRQI-AHRGGERFPMASTFKLLLAAQTLRRVD +QGHDKLDRRVTYTKKDLVTYSPVTEPHADGALTVEELCAGTMTLSDNTAANLLLASNGGP +PALTAYVRSLGDSITRLDRNEPSLNEAKPGDPRDTTTSVAMVHCIQALALGQALSPASRE +KLQGWLLGNKTGDKRLRARLPEGWKAGEKTGTASRGTSNDAGVFWPPARKPIVVSCYLTG +GEAPPEQRDAAMAEIGALVAQ-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus sp. AFS094611 TaxID=2033516 RepID=A0A2A7DZS2_9BACI +----YKEFSQLEKKYDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKSFTVGNALPDHKRY +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKDAPYDNQLIAEAAEVIVN-- +>[subseq from] Beta-lactamase n=2 Tax=Rhizobium TaxID=379 RepID=J0VK68_RHILT +-dNVEKRLAALEKRTGGRLGVSVLDTETSISF-NYRGSEAFPMCSTFKALAAGFVLARVD +KGEEKLDRRVTYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTSPDAMLDTLGNLTLGSILTEASCD +RLIAWLVASTTGGERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATVPVKELNPVFAEVGKMIVE-- +>[subseq from] Beta-lactamase 1 n=1 Tax=Amycolatopsis sp. YIM 10 TaxID=2653857 RepID=A0A5P9PXT8_9PSEU +--AVEQEFNRLQTQHDARLGIYAVDTGSGKSI-AFRADERFAYASTFKALAAAAVLDTTT +--PQQLDEVVRYTAEDMLANSPITEQHLDTGMTLRDLCDAAVRYSDNTAGNLLLRHVGGP +AGLDAALTAIGDDVTSVDRYEPDLNSAIPGDVRDTSTPRAMAGNLRQYVLGDALAEDDRA +VLTDWLRRNTTGATLIRAGVPGDWVVGDKTGSGYYGGRNDIAVLWPPNRAPIVMAVMTSR +DEPRAKRADALLADAARVAVT-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A7ISN1_BACCE +--TVNHSFSKLEKEFNAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALASSLQAFTLGDVLSTEKRS +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKSDDKLIAEATQIVLD-- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000D744E27 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLLRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium etli TaxID=29449 RepID=UPI000A28FA5F +--NVEHRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGEENLERRVTYGREKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTSPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATASVKDLNSIFAEVGKMITE-- +>[subseq from] Beta-lactamase n=1 Tax=Raoultella electrica TaxID=1259973 RepID=A0A514ER89_9ENTR +heATVATVKHAESQLQGRVGYAELDLASGQLLaGYRPDERFPMMSTFKVLLCGAVLSRVD +AGEEQLDRRIHYRQQDLVEYSPVTEKHLTAGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTAFLRHSGDQTSRLDRWETELNEARPGDVRDTTTAQAMARTLRNLLIGRVLSPASQQ +QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAGRIVVIYLTG +TPASMDERNKQIAAIGKTLVAHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C2W5A7_BACCE +--TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKSDDKLIAEATQIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus formosus TaxID=54913 RepID=A0A220MBB9_9BACL +--AMDQKFAALENKFDARLGVYAIDTETDLAV-AYHEDERFAFASTYKALAAAAVLHQKP +--LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP +KGFESALRQIGDGVTTSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGNVLSSDKQK +ILIEWLQGNTTGAKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR +DKQDATYDDALIAEATKIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus sp. NRRL NRS-603 TaxID=2126351 RepID=A0A2P7X9Z6_9BACL +--AMDQKFAALENKFDARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP +--LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP +KGFESALRQIGDGVTTSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGNVLPSDKQK +ILIEWLQGNTTGAKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSKR +DKQDAAYDDALIAEATKIAVD-- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=Q6R5M7_KLEPN +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAGIGAALIEHw +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000E2D1F9C +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=A0A0E3UEI1_9XANT +---LRAQWAEIERRSGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVTIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQLASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase KPC-13 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=F2X6V8_ENTCL +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLGTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase KPC-11 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=D7RIC6_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVLWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI0007CC300D +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDMRDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Allonocardiopsis opalescens TaxID=1144618 RepID=A0A2T0QEZ7_9ACTN +---FEPQFQQLESEYDALLGVYAVDTGTERTI-SYNADQRFAYASTFKALAVGAVLQQNT +--IEELEEVITYTSDDLVNHTPITEQHVDTGMTLRELCDAAIRYSDNTAANMLFEELGGP +SGLDAALEGIGDDVTHVDRIEPHLSDYEPGDIRDTSTPQAMATSLRAYTLGEVLPPDERA +ILVDMLRGNTTGDELIRAGVPADWEVGDKTGSGSYGTRNDIAILWPPDREPIVVAIMTSN +DDPDAEYDNALIADAATVIAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A4Q8XWD1_RHILE +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGDENLDRRVSYGKDKLVDYSPISEKHAGTDMILAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=Q63B80_BACCZ +-qATHKEFSQLEKKFDAQLGVYAIDTGSNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRKMGDRITMSDRLETELNEAIPGDIRDTSTAKAVAMNLKAFTAGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas abietaniphila TaxID=89065 RepID=A0A1G7SCN8_9PSED +--SIEQGLAELERRHGGRLGVAILDTGSQRLI-AHRGDERFAMCSTFKALAAAYVLARVD +RKEEDLSRVIVYGKDQLVPYSPTTEKHTGEGLSVGSICEAAVTLSDNTAANLLLDSFGGP +PALTAWLRSTGDQVTRLDRREPDLNENRAGDPQDTTTPIAMLQSLRTLILGDVLSGASRD +QLIAWLVSNTTGDKKLRAGLPKAWRVGDKTGSNAKNASNDVAIVWPTGRPPLVVSVYYDH +PRLGDDQVNTVIADVARLIAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium oligotrophicum S58 TaxID=1245469 RepID=M4Z7N3_9BRAD +--DLQATIAGIEADSGGRLGVALLDTASGALS-GHRLDERFPMCSTFKALLAAAILGKVD +VGTEQLARRIPIAQGDILSYAPVTKAYVGTSLSVGELCDAAVTLSDNTAANLLLATLGGP +AGLTRAIRGFGDAVTRLDRIEPELNESVPGDPRDTTTPAAMAQTLAKLTTGNALLPASRD +QLTAWLIACKTGGARLRAGLPAEWRVGDKTGTGEHGSANDVAVIWPSGRAPVIVTSYLTE +TKAGDDRRNAVHAAVGRAVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI001030EC10 +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGDENLDRRVNYGKDKLVDYSPISEKHAGTDMILAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +ATVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Thalassospira xiamenensis TaxID=220697 RepID=A0A285RSF4_9PROT +-dRLTDAIHAVETRLDARVGVSILNVENGREW-QYRADERFPLTSTVKLLACAAILHKVD +LGTETLDRRIIYGVEDLVTYSPTTEKHVDGGMTIGELCEATLHLSDNTAANLILDALGGP +DELTAYLRDIGDDVTRLDRIEPDLNTAKPGDPRDTTTPDAMRASLAYLLLGDALSADSRQ +LLEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPEQKPVIVAIYITQ +TSASMDERNAAIADLGQEIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces thermoviolaceus TaxID=1952 RepID=UPI00143A7602 +-qEAADRLGALEDRYGARLGVHARNVRTGQVV-AHRADEVFAMCSVFKTFAAAAVLADQD +-RCTPLDRLVAYPPADLLPNSPRTEEHVDTGMTVDDLCAAAIRYSDNTAGNLLLRQIGGP +AGLTRFFRSLGDRVSRLDRWEPDLNTAVPGDPRDTTTPQALGRLLERLTLGDALAAADRA +RLVDWMKGNTTGDGRIRAGVPEGWTVADKTGTGSYASAHDVGVAWTTRSTPVVLVVLSSK +ETADAPVDEALLADAARVVAD-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C796C80 +-----EQIKLSESQLSGRVGMIEMGLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLSAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B6E133_KLEPN +-----EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000A764367 +-qATHKEFSQLEKKYDARLGVYAFDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVIMSDRFETELNEAIPGDNRDTSTAKAIATNLKAFTVGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=UPI0013D55BB1 +--TIEEQLSTLEKNSQGRLGVALINTKDNSQI-TYRGDERFAMASTSKVMAVAAVLKESE +KQAGLLDKHMTIKKTDLVTYSPITEKHLATGMTLAQLSAATLQYSDNTAMNKILDYLGGP +SKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPLTMATSLQLLTLGDALGQYQRQ +QLITWLKGNTTGDQSIKAGLPNNWVVGDKTGSGDYGTTNDIAIIWPENQAPLILVVYFTQ +QKQNAKPRKDIIVKATEIVTKEy +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea TaxID=53335 RepID=UPI0006DD4147 +--TLKSQFETLENKSGGRLGVTVVDTSDGSEY-SWRGNERFPLCSTSKVMAVAAILKKNE +SDHSLLDKKIHINKSDMVNYNPFTQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP +QQATHFARTIGDKAFRLDRKEPELNTAIPDDVRDTTTPSAMADTLNKLVLGTALKGEQRA +KLSEWMKGNTTGANSIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKDQAPIILTTYFTQ +KDKDAVARKDVLASAAKLVVD-- +>[subseq from] Beta-lactamase n=2 Tax=Rhizobium TaxID=379 RepID=L0LIB6_RHITR +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAAGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAIKEDPRDTTTPDAMLDSIGLLTLGNTLSETSRE +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE +ATAPAKDVEAVFAEIGKIVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. 7Q-K02 TaxID=2571747 RepID=UPI001315EDDF +--ALEKPLAAIEAQVGGRLGVAMLDTASGHVG-GWRLHERFPMCSTFKVLLASAVLTRKD +HGKEDLARKVVYTHAQVVSYSPVSGPRAGGEMTVAELCEAALTRSDNTAANLLLESIGGP +PAITAFARSLGDPVTRLDRNETTLNEAIPGDPRDTTMPAAMVANLRELLLGERLSSASRE +QLIAWLVANKTGDARLRAGLPKDWRLGDKTGTGDRGTANDVAIIWPTGRAPVLVTTYLTG +ATASSAQRDAAIAQVGVLLAHRy +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE2B5A5 +-dEINRRMDALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP +AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMLDTLGNLTLGSALSEPSRD +KLVAWMVANTTGGARLRAGLPDTWKIGDKTGTGSNGSAADIAVVWPPGHGAILVAAYLTQ +AKAPVSEINPVFAEVGKIVG--- +>[subseq from] SED family class A beta-lactamase n=1 Tax=Citrobacter farmeri TaxID=67824 RepID=UPI000F65CED2 +--QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRADERFAMCSTSKTIVVAAVLKQSE +TQHDILQQKMTIKKTDLTNWNPVTEKQVNKEMTLAELSAATLQYSDNTAMNKLLEHLGGT +GNVTAFARSIGDATFRLDRTEPELNTAIPGDERDTTSPLAMAKSLHKLTLGNALADMQRA +QLVAWLKGNTTGGQSIRAGLPESWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ +PQQDAKGRKDILAAAAKIVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora citrea TaxID=47855 RepID=A0A1C6UQV2_9ACTN +----EHEFRQLEKRFDARLGVYAIDTGSGRTV-EYRADERFAYASTFKALAAAEILDETT +--DAELDRVVRYSADDLVTYSPITERHVATGMTLRAIADAAVRYSDNTAANLMLRHLGGP +QKFEKELREVGDKVTDPARYETELNEARPGDRRDTSTARALAESLRAYAVGDALEPADRD +ILNGWLRGNTTGGELIRAGVPDGWVVGDKTGAGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEKDASYDNALIAEATKAVLAGw +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000E2E2AE5 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSTRSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009E36D4F +-qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKHN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. GV021 TaxID=2135749 RepID=A0A2T5ZJ55_9PSED +--AIQQQLADLESRHGGRLGVAILDTASQRLI-SHRGDERFALCSTFKCLAAAHVLARVD +RKQEDLSRRIVYSAEQLVAYSPTTELHVGGQLSVGSLCEAAMTLSDNTAANLLLDSMGGP +EGLTAWLRSIGDTRTRLDRREPDLNENRPQDLRDTTTPVAMLHTLNTLVLGDELTLPSRD +QLTAWLVNNQTGDKKLRAGVSGGWRVGDKTGSGSNNATNDVAVIWPGDRPPILVTAYYTG +SKASADQINAVMADIGRLA---- +>[subseq from] Beta-lactamase n=1 Tax=Phytobacter diazotrophicus TaxID=395631 RepID=A0A4R4AYV1_9GAMM +-----ETVKKAEDQLNARVGYAELSLANGQMLgSYRPQERFPMMSTFKVLLCGAVLSRVD +AGQEQLARRIQYRKQDLVAYSPVTEKHLTDGMTLAELCSAAITMSDNTAGNLLLSAIGGP +SELTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQMLRQLLNGKILTPASQQ +QLMAWMEADKVGGPLIRSVMPAGWFIADKTGAGERGSRGIVAALGPDGKPARIVVIYITE +TQATMDDRNKKIADIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus sp. tmac-D7 TaxID=2591462 RepID=UPI001144BF69 +----DQAFVQLEDEYDARLGVYAIDTGTGRTI-AYRPDERFAYASTYKALAAGAVLLKSS +--IEELDEIITYSSNDLVTYSPITEKHVSTGMTLREISDAAVRYSDNTAGNLLFKRLGGP +AGFEAILKQIGDTVTQADRYETELNEAVPGDDRDSSTPRALATSLHAFTVGDALPANKRT +ILTDWLRGNTTGDELIRAGVPEGWTVGDKTGAGNYGARNDIGIVWPPNGDPIVIAILSSR +DTKDAGYDNSLIAQAAKTALD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. CDB3 TaxID=360310 RepID=A0A1V9W5V4_9BACI +--ATYQEFSQLEKEFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYSKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAKVVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia caledonica TaxID=134536 RepID=UPI00037C3C79 +--TIRARLREIEADSGGRLGVAIVDTTSGLHT-GLHADERFPMCSTFKLLVAGAILARVD +RGEENLQRRIVYSQSELVPNSPATSKHTRARMSVGDLCKAAITLSDNTAANLLLASFGGP +AALTEFARSLGDGITRLDRIEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA +QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIVWPPGHGPILVAVYLTE +TAGDAARCNAAIASVGALVAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas melonis TaxID=56456 RepID=A0A2S7DHQ4_9XANT +--MLRAQWAEIERGTGGRLGISVLDSATGWRL-GQRENERFPMCSTFKFVLAAAVLQRVD +QGKLSLAQPVGIRASDMLAHAPVTERHVGGSLSVGELCRATMIHSDNPAANLLFPLVGDP +AGLTAFLRSIGDAKTRSDRYEPEMNRFAPGEPRDTTTPAAMASTLRTLLLGDALAPASRK +QLTDWMIDNRTGDDCLRAGLPRGWKIGDKTGSNGTDTRNDIAIVWPPKGPPLLLTTYLNG +AKVDDAARDAALKQVAATVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKE6_9BACT +--ETLVKVKDAGDQLGARVGYIELDLNSGKILeSFRPKERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. K2R01-6 TaxID=2320861 RepID=A0A418W7H8_9SPHN +---FARRIAALEAANGGRLGVAVLDTSSGARF-SHRGDERFPMCSTFKFLLAAATLARVD +RGQEKFDRRIRYAADQIVTHSPVTSEHVGAPLTVGELCAATMTTSDNTAANLLLTALGGP +TAFNAFARNLGDRYTRIDRIEPWLNEAMPGDLRDTTTPAAMLGNLRRLLTRSTLTPGSRD +ILIGWLVANQTGGTRLRAGVPADWRVGDKTGAGERGTVNDIGILWPAGRAPILVASYLTA +SPLPFETNSAVHADVARAIAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. BK315 TaxID=2512135 RepID=A0A4R3GEY1_9RHIZ +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAAGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRE +QLVNWLVANTTGNNRLRAGLPKDWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE +ATAPAKDVEAVFAEIGKIVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. 105MF TaxID=1151120 RepID=UPI00037EC1F9 +--TVNHSFARLEKEFDAKLGIYALDTGTNQIV-TYRSDERFAYASTHKALAVGILLQKKS +--IEDLDERIVYTSEDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRAIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium giardinii TaxID=56731 RepID=UPI00035E8157 +-nDINRQLASLEKRTGGRLGVSVLDTKSNVSF-GHRQDERFAMCSTFKALAAAFVLARVD +KGQETLGRRIVVSKADLHAHSPVAEKHVGDGMTVGELCDAAVTYSDNAAANLILASFGGP +DGLTAWLRSIGDETTRLDRTEPALNEAKPGDPRDTTTPAAMMRTLGKLLLEDVLSPSSRD +QFAAWLVANRTGDRRLRAGLPTNWTIGEKTGTSGHGEAGDVGFMRPPKGQTILASVYIAE +APKPVKELEPIFAEVGKLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. OK605 TaxID=1855317 RepID=UPI0008EB3AC7 +---AEAQLAELERASGGRIGVAGLHTGSGARF-QHRAHERFPMCSTFKLMLAAAVLERSA +KDASLLSRQLSYGKSDLIANSPVTEKHVATGMNVADLCAATIQYSDNAAANVLLKLLGGP +PEVTAFSRRIGDQTFRLDRTEPELNTSIPGDLRDTTTPAAMSDSVQRLVLGDALGAPQRD +QLKTWLLGNTTNKERFLAGVPAGWKVGDKTGGGSYGSNNDVGVLWPPAGAPLVLSVYLTF +PEKDAKTRNDVVASATRIAVT-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0009ABFFF8 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKDATYDNKLIADAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0014422AF1 +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAALCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVATVYISE +TTVPVTELNPLFAEVGRMIVE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B51AEC +-qATHKEFSKLEQKFDARLGVYAIDTGSNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVNYSPVTEKYVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAAIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] 3G61_DB15V4 n=1 Tax=synthetic construct TaxID=32630 RepID=UPI00077DEFC1 +-----VKVKDAADQLGARVGYIELDLNSGKILeSFRSEERFPMMSTFKVLLAGAILSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELASAAITMSDNTAANLLLTTIGGP +KGLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTPASRQ +QLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIVAALGPDGKPSRIVVIYTTG +SQATMDELNRQIAEIGASLIKGw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. E(2018) TaxID=2502239 RepID=UPI0010F8445D +--KTEKKFMQLEKQFDARLGIYAIDTHTNRTV-TYRPDERFAYTSTFKALAAGVVLQQKS +--IEELEEVITYTEDDLVTYSPITEQYVDTGMTLREICDAAIRYSDNTAGNLLLQELGGP +NGFEKALRDIGDNVTEADRYETDLNSAIPGDIRDTSTARALAINLKAFTADDVLPNDKRT +ILTDWLRRNTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPNREPIIIAILSSR +DTQNATYENELIAKAAKVALNAf +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax avenae subsp. avenae TaxID=80870 RepID=A0A2R4F6K8_9BURK +--ALARAMQEIEASVGGRLGVALLDMATGRQG-AHRGDERFPLCSTFKLVLAAHVLRRVD +QGQERLDRRITYGQSDLMEYSPATERHVGGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP +LGLTAWLRSLGDSQTRLDRMEPALKDVPPGEVRDTTTPRAMARTVWAVTQGEALSAAARA +QMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDIGLFWPPDRGAVMVSCYLTG +SPAPAEQRDAALARVGALAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. 4M9327F10 TaxID=2502223 RepID=UPI0010F7144B +----EARLAQLEQSAGGRLGVFALNTADGTQI-GHRADERFPFCSTFKVILIGAILARSA +QAAGLMQQRIHYTAGEVVHYSAVTAEHVSDGMTVAELCAAAIQRSDNTAANLLIRLLGGP +DAVTAYARSLGNPVFRLDRLETALNDAVPGDPRDTASPAAMARSLQALTLGEALPLAQRT +QLLDWLRGNRMGAQRIRAALPAGWTSGDKTGTGDYGTANDLGLIWPPSRAPILLGIYHTQ +AQQDAKARDDVIAAAARIVV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus (strain Q1) TaxID=361100 RepID=B9J113_BACCQ +-qATHKEFSQLEKKFDARLGLYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. HY001 TaxID=2597691 RepID=A0A556CAI5_9BACI +---TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQKNS +--TEKLNEVVTYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQIEDRVTKSDRLETELNEAIPGDKRDTSTAKAIATNLKDFTVGNALPDQKRN +ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI000E2CC650 +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAELPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAVIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=Q5GJ48_RAOOR +heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD +TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLNVGELCAAAITLSDNTAANLLLTTLGGP +QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ +QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA +TPASMDERNKQIAAIGETLVRHw +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=unclassified Raoultella TaxID=2627600 RepID=UPI0013309E41 +hdATVNQVKAAERQLKARVGYAELDLASGRLLaSYRPGEHFPMMSTFKVPLCAAVLARVD +AGEEKLDRRIRYRQQDLVDYSPVTEKHLADGMTVAGLCAAAITLSDNTAANLLLASVGGP +QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTSTPQAMAKTLRNLLTGSVLSAASRQ +QLRSWMVDDKVAGPLLRSTLPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMEERNRQIAGIGETLVKHw +>[subseq from] GIL family class A beta-lactamase n=1 Tax=Citrobacter sp. wls613 TaxID=2576436 RepID=UPI0010CA8DE3 +-pTTLNKVKEAESQLTARVGYAELDLTSGEILeSYRLQERFPMMSTFKVLLCGAVLARVD +AGKELLDRRIPFSRRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGP +QGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILTTTSQQ +QLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYVTE +SQATLEERNRQIAGIGATLIQHw +>[subseq from] Beta-lactamase n=1 Tax=Raoultella sp. BIGb0138 TaxID=2485115 RepID=A0A4R3ZF99_9ENTR +heATVSKVKEAESQLQARVGYAELDLSSGRLLtGYRSAERFPMMSTFKVLLCGAVLSRVD +TGEEKLDRRIDYRQQDLVEYSPVTEKHLSDGLTVAELCAAAITLSDNTAANLLLATLGGP +QGLTAFLRRSGDRTSRLDRWETALNEALPGDARDTTTPEAMAQTLRQLLTGNVLSAASQR +QLQRWMVDDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIVAALGPDGKASRIVVIYLTE +TKASMDERNKQIAAIGETLVQRw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI00027AAF2B +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEGLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC00469 TaxID=2487415 RepID=A0A3R9SQI6_9ACTN +-qEAADRLGALEDRYGARLGVHARNVRTGQVV-AHRADEVFAMCSVFKTFAAAAVLADQD +-RCTPLDRLVAYPPADLLPNSPRTEEHVDTGMTVDDLCAAAIRYSDNTAGNLLLRQIGGP +AGLTRFFRSLGDRVSRLDRWEPDLNTAVPGDPRDTTTPQALGRLLERLTLGDALAAADRA +RLVDWMKGNTTGDGRIRAGVPQGWTVADKTGTGSYASAHDVGVAWTTRSTPVVLVVLSSK +ETADAPVDEALLADAARVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF31A57 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGALLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013252704 +-----------ESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +XGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAXXRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B1E2I3_BACCE +----YKEFSQLEKKYDARLGVYAIDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRN +IFTEWMKGNATGDKLIRAGVPTNWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAKVIVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. S1 TaxID=1641859 RepID=UPI00131D52A8 +--AIRQRLAQIEVESGGRLGVSILDTTSGLHA-GLRTDERFPMCSTFKLLAAGLVLTRVD +HGQEDLERRIVFSKSDLVPYSPATSQHTRERMSVADLCKAALTLSDNTAANLLLASFGGP +AALTAFARSIGDGITRLDRNEPTLNEATPGDPRDTTTPSAMLGNLRELLLGERLSSLSRA +QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDIAILWPPGRGPILVTVYLTE +TSGDAARCNAAIASVGALVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Shigella sp. FC1967 TaxID=1898041 RepID=UPI00086F3D4A +-nTIEAQLSTLEKYSQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAILKESE +KQAGLLDKNITITKSDLVAYSPITEKHLVTGMSLAELSAATLQYSDNTAMNKILDYLGGP +AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQVLALGDALGGSQRQ +QLVTWLKGNTTGDHSIKAGLPKQWIVGDKTGSGDYGTTNDIAVIWPDNHAPLILVVYFTQ +QRQDAKHRKDIIAKVVEIVTKPf +>[subseq from] class A broad-spectrum beta-lactamase OKP-B-21 n=1 Tax=Klebsiella TaxID=570 RepID=UPI000B4184C2 +-----EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNEQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A162P3V9_BACCE +---TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQKNS +--TEKLNEVVTYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQIEDRVTKSDRLETELNEAIPGDKRDTSTAKAIATNLKDFTVGNALPDQKRN +ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3YA67_KLEPN +-----EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNEQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. b14 TaxID=1761775 RepID=A0A1R3VVL8_9BURK +-----EALAVLEARMGGRLGVCAIDTGSGARL-VHRAEERFPFCSTFKAVLAAAVLARSG +DTSDWLSQRVRYGSADVVSYSPISGQHVGAGMRIDEMCAATLQYSDNTAANQLMKVLDGI +DAVTAFARSVGDATFRLDRWEPELNTAIPGDVRDTSTPAAMADTLRAVMLGNVLRPWQQQ +RLQQWMLGNRTGDKRIRAGVAAQWRVADKTGTGEYGTTNDIGVLWPPERAPIVLSIYFTQ +PQQDAPARDEAIEQATRIVVD-- +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Bacteria TaxID=2 RepID=A0A5Q2F6E6_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTPASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEDBACE +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTSDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Citrobacter portucalensis TaxID=1639133 RepID=UPI0008F83F29 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTSGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Class A beta-lactamase n=2 Tax=unclassified Rhizobium TaxID=2613769 RepID=A0A437N5N5_9RHIZ +-dDIEKRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFALARAD +KGEESLDRRVTYGRDKLVDYSPLSEKHAGADMTITELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTTPDAMLDTLGNLTLGSILTEASSD +RLIAWLVASTTGGERLRAGLPKEWKVGDKTGTGQNGSLGDIAVIWPPDRSPIVAAVYIAE +ATAPVKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia caledonica TaxID=134536 RepID=UPI000B3F91C6 +--TIRARLREIEADSGGRLGVAIVDTTSGLHA-GLHADERFPMCSTFKLLVAGAILARVD +RGEEDLQRRIVYSQSELVPNSPATSKHTRERMSVGDLCKAAITLSDNTAANLLLASFGGP +AALTEFARSLGDGITRLDRIEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA +QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIVWPPGRGPILVAVYLTE +TAGDAVRCNAAIASVGALVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax oryzae TaxID=862720 RepID=UPI0003708DC8 +---FARAVQEAEASVGGRLGVALLDVATGRQD-AHRGDERFPLCSTFKLVLAAHVLRRVD +QGQERLDRRITYRKSDLMEYSPATERHVDGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP +LALTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSSAARA +RMLGWLVGNRTGDRRLRAGMPEGWRVGEKTGTGPRGTSNDIGLFWPPDRDAVMVSCYLTG +SPAPAEQRDAALARVGALAA--- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium indicum TaxID=1775910 RepID=A0A0J6RJ49_9RHIZ +--DAVARLAQFERRDGGRLGVEVRDTATGRRF-GHRADELFPMCSTFKAVAAAAVLARAD +KGQDDLNRRIAYTRDDLLSYAPVTSKHVESGLTLAELCAAAVVWSDNTAANLMLATLGGP +GGITTFARAHGDTVTRLDRTEPTLNTAIPGDPRDTTSPAAMVGLLDNVLLGKALSAESRT +KLVGWMHESPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG +SPAEPAARDALHAEVGRLIARSf +>[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia TaxID=1822464 RepID=I5CU60_9BURK +--ALEKQLAQIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD +QGKEQLGRTIAYSKEVVVANSPVSGPRAGGDMTVAELCEAAITRSDNTAANLLLDSIGGP +AALTAFARGIGDRITRLDRNEPTLNEALEADPRDTTTPAAMLADMRALLLGDHLSAASRE +QLTAWLAGNKTGDARLRAGLPKAWRVGDKTGTGERGTSNDIAVIWPEGRAPILVAAYLTG +ATATSTQRDAAIAQVGALVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1G4L245_BACCE +hqATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRQ +VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAVLSSK +EEKEATYDNQLIAEAAEMIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=R4S362_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLSACWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKI7_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSLRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSSVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. OK202 TaxID=1884311 RepID=A0A1H7E6S3_9BURK +---AEAQLAELERASGGRIGVAGLHTGSGARF-QHRAHERFPMCSTFKLMLAAAVLERSA +KDASLLSRQLSYGKSDLIANSPITEKHVATGMNVADLCAATIQYSDNAAANVLLKLLGGP +PEVTAFSRRIGDQTFRLDRTEPELNTSIPGDLRDTTTPAAMSDSVQRLVLGDALGAPQRD +QLKTWLLGNTTNKERFLAGVPAGWKVGDKTGGGSYGSNNDVGVLWPPAGAPLVLSVYLTF +PEKDAKTRNDVVASATRIAVT-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A443WXH8_KLEPN +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHY1_KLEPN +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. TaxID=391 RepID=A0A5C7U540_RHISP +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAAGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHADADMTVAQLCGAAITLSDNTAGNLLLESFGGP +AALTAWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDTIGLLTLGNTLSETSRD +QLVNWLVGNTTGDNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAPAKDVEAVFAEVGRIVT--- +>[subseq from] class A broad-spectrum beta-lactamase OKP-B-36 n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI00073B170F +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=J8X555_9BACI +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDVKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A679H1W8_9BACI +----NNSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVGTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFILGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEBB9BE +--TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKESLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKSDDKLIAEATQIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus pseudomycoides TaxID=64104 RepID=UPI000BF4356D +--TVNHSFARLEKEFDAKLGIYALDTGTNQII-TYRSDERFAYASTHKALAVGILLQKKS +--IEDLDERIVYTSEDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRAIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase SHV-34 n=1 Tax=Escherichia coli TaxID=562 RepID=BLA34_ECOLX +-----EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADGRFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase LEN-58 n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000E2CB9BC +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLFDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Shigella sp. FC1655 TaxID=1898038 RepID=A0A1D3DEB3_9ENTR +-nTIEAQLSTLEKYSQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAILKESE +KQAGLLDKNITITKSDLVAYSPITEKHLVTGMSLAELSAATLQYSDNTAMNKILDYLGGP +AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQVLALGDALGGSQRQ +QLVTWLKGNTTGDHSIKAGLPKQWIVGDKTGSGDYGTTNDIAVIWPDNHAPLILVVYFTQ +QRQDAKHRKDIIAKVVEIVTKPf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SRB_331 TaxID=1969379 RepID=A0A328LVH6_9BACI +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILTSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1JIQ2_BACCE +---TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQKNS +--TEKLNEVVTYTKEDLVDYSPVTEKHVGTGMTLGAIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDNRDTSTAKAMATNLKDFTVGNALPDDKRS +ILTDWMRGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8RST3_BACCE +--TVNHSFAKLEKEFDAKLGIYALDTGTNQIV-TYRSDERFAYASTHKALAVGVLLQKKS +--IEDLDERIVYTSEDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRAIGDTVTNPERFEPELNEVPPGDTHDTSTPKALATSLQAFALGDVLSTEKRE +LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD102 TaxID=1053228 RepID=J8JHT5_BACCE +-qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKHN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0009BA7A54 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mesonae TaxID=1193713 RepID=UPI000A0612D4 +--QIHRKFADLEHKFDARLGVYAIDTGTNRTV-SYRPNERFAYASTFKALAAGALLQHYS +--LDQLDELVKYSREDIVTYSPVTELHVDTGMTLREVIEAAVRYSDNTAGNLLLKKLGGP +KGFETALRQIGDNVTQADRYETELNSAVPGDPRDTSTPKALAASLRAFAVSDLLPSEKRT +ILIDWMRGNATGDALIRAGAPKGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAILSSR +DTQNATYDNALIAEAAKVALN-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-27 n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1P8C558_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPRSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI001033E6E3 +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2B1AQH6_BACCE +hqATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRQ +VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAVLSSK +EEKEATYDNQLIAEAAEMIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Thalassospira xiamenensis TaxID=220697 RepID=UPI000DED6607 +-dRLTDAIHAVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAILHKVD +LGTETLDRRIIYSVEDLVTYSPTTEKHVDSGMAIGELCEATLHLSDNTAANLILDALGGP +DELTAYLRDIGDDVTRLDRIEPDLNTAKPGDPRDTTTPDAMRASLAYLLLGDALSADSRQ +LLEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPEQKPVIVAIYITQ +TSASMDERNAAIADLGQEIA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKH4_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYPPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00143185C3 +---LRAQWAEIERGTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPARAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. H4 TaxID=2035449 RepID=A0A2A6R6S8_9RHIZ +--NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPAAMLDTLGNLTLGSVLTEASCN +RLIACLVASTTGGERLRAGLPADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATVPVKDLNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZRK9_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNXGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQI----------- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium esperanzae TaxID=1967781 RepID=A0A246DT74_9RHIZ +--NIERRLATLEKRIGGRLGVSVLDTQTSISF-GYRGGETFPMCSTFKALAAGFVLARVD +KGQESLDRRVTYGRDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +PALTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTSPDAMLDTLGNLTLGSVLAEPSSD +RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPAKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2H3NF61_9BACI +-----DSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSKH +DKEDAKYDDKLIAEATKIVLE-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylibium sp. CF468 TaxID=1500262 RepID=UPI000647C16D +-----PRWAAIEAESGGRLGIAVLDTATGRFD-GHRLGERFPMCSTFKWLAAALALQRVD +AGLERLDRRVAVRREMLVNHSPVSEKHVGGNMSIAELCEAAVLVSDNAAANLLLASFGGP +AAITRYARTLGDTQTRLDRTEPALNEARPGDPRDTTTPRSMAIALQSALLGTALSEASRA +RLVAWMEAVRTGTDRLRAGLPPGWRAADKTGTGARGTTNDVAVVWPPNRAPLVITAYLTD +SQADAKRLNAALAAVAREAA--- +>[subseq from] Beta-lactamase n=1 Tax=Curvibacter sp. TaxID=1888168 RepID=A0A353Y3B1_9BURK +--------REIEAEASGRLGVAVLDTATGHLQ-GHRLDERFPLCSTFKWLLGAHVLRRVD +LGLERLDRVIVYGPDAIIPWSPVTAQRVGQGMTLAELCEATITLSDNAAANLILQTLGGP +QGWTQYVRSLGDTVTRLDRTEPELNAATPGDPRDTTSPRAMVALLQGVVLGDALTPASRA +QLVTWMQATQTSGQRLGAQLPAGWRLGSKTGTGARGSTNDVGVYWPPDRAPIVVAAYLTQ +SPAAEATRNRAIARVARAVIS-- +>[subseq from] Beta-lactamase n=1 Tax=Photorhabdus luminescens BA1 TaxID=1393736 RepID=A0A022PLW1_PHOLU +--SLHKQLAELENSTKGRLGVTLINTVNGQEI-QYRGDERFPFCSTFKLILVAAVLHKSM +SQSELLAKHIHYRESDLLSYAPIARKNLNQGMSVAQLCAATVQYSDNTAANLLIKELGGL +EVVNHFTQGIDDPAFRLDRCEPDLNSAIPGDLRDTTTPAAMATSVRKIVLGEVLAAPQRE +QLIVWLKGNTTGDASIRAGAPADWVVGDKTGGGDYGTTNDVAVLWPPKGAPVVLAVYFTQ +PQQDAESRRDVLASATRLVMAH- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. GAS332 TaxID=1882750 RepID=A0A1N6LHK4_9BURK +--AIRQRLAQIEVESGGRLGVSILDTTSGLHA-GLRTDERFPMCSTFKLLAAGLVLTRVD +HGQEDLERRVVFSKSDLVPYSPATSQHTRERMSVADLCKAALTLSDNTAANLLLASFGGP +AALTAFARSIGDGITRLDRNEPTLNEATPGDPRDTTTPSAMLGNLRELLLGERLSSLSRA +QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDIAILWPPGRGPILVTVYLTE +TSGDAARCNAAIASVGALVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFA58A2 +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--MEDLNQRILYNREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRS +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKFDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q1WBW3_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASWQ +QLIDWVEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLI--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD5E4AA +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAAGFVLARVD +QGTEKLDRRVTYGKDKIVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRE +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE +ATAPAKDVEAVFAEIGKIVVD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKF0_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFRVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHPTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHY6_KLEPN +-----EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. viciae TaxID=387 RepID=A0A4R0BL75_RHILV +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFSMCSTFKALAAAFVLARAD +KGEENLDRPVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB24CE +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAAGFVLARVD +QGTEKLDRRVTYGKDKIVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRE +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE +ATAPAKDVEAVFAEIGKIVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudolabrys taiwanensis TaxID=331696 RepID=A0A345ZT82_9RHIZ +---AETKLRALEHQHGGRLGVFVRDTGSQAQL-AHRADERFPMCSTFKFLLAAAVLKRVD +DGKTRLDHEIDYGDKDLLDYAPVAKQHVASGLSVAALCAAAVVWSDNTAANLLLNHLGGP +QAVTAYAHSLGDMLTRLDRMEPALNTVPAGDPRDTTSPRAMVGDLQAILVGDALSPVSRQ +RLEDWMVAAQTGRERLRAGVPATWRVGDKTGTGPNGSTNTIAILRPPQRAPLLAAIYYTS +SKAPLKDREAVHAEIGRLIVESf +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium tropici TaxID=398 RepID=A0A5B0VV53_RHITR +--DVDKQLTDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHVGTDMTVAELCGAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGPILVTTFIAE +ATASARDIEAVFAEVSKIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. UNC69MF TaxID=1449047 RepID=UPI0012E00CDF +---TNQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS +--NEKLNDIIRYTKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDKLIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Chelativorans sp. lm92 TaxID=2681495 RepID=UPI0013D2BB13 +--DAEAKLAALERAHDGRLGVAILNLATGARA-GHRSDERFLMCSTFKALAAALVLARVD +RGEEALDRRITFSKADIAAWSPATETRVGGKMTVAELCEAAVTLSDNTAANLLLRSFGGP +QALTAYARSLGDEVTRLDRFEPALNEHGPDDIRDTTSPAAMLETLRTLLFADVLSKPSRS +RLAAWLIANKTGGARLRAGLPENWLVGDKTGTSGSGAVNDIGVAWPPDRAPIVVTAYCEL +PAISGDERNAVIAEIGRIAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI001249AFD0 +--ATHREFAQLEKKFDARLGVYAIDTGTNQTV-SYRPNKRFAYASTYKALAAGAVLQQNS +--IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP +KGFEKALRQIGDNVTVANRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK +ILTDWMRGNATGDKLIRAGVPKDWEVDDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR +DKKDATYDNELIAQAAKVTIN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sorangium cellulosum TaxID=56 RepID=A0A150TNI2_SORCE +---AAPALARIEAQVGGRLGVAALDTATGARI-AHRAAERFAMCSTFKTLLAACILARVD +QGQLRLDHRVTYRASDLLDHAPVTRAHLAQGLTVEELCAAVVEISDNTAANLLLAQIGGP +AGLTAYLRGLGDEVTRLDRNELALNENVPGDPRDTSTPDAMTDTVRAILVGDALQRASRE +RLASWMVRSTTGLARLRAGLPKDWVIGDKTGTGN-GIANDVAVAWPPSRPPIVIACFVDA +PSASADARNAAHADVARAVAEAf +>[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia terrae TaxID=311230 RepID=A0A2I8EIK4_9BURK +--ALEKQLAQIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD +QGKDQLERKIVYSKDVVVANSPVSGPRAGSDMTVAELCEAAITRSDNTAANLLLDSIGGP +AALTAFARGIGDRTTRLDRNEPTLNEALEADPRDTTTPAAMLADMRALLLGEHLSAASRE +QLTAWLAANKTGDTRLRAGLPKAWRIGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG +ATATSTQRDAAIAQVGALVAN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=A0A658AX17_9ENTR +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRHIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Enterobacteriaceae bacterium S05 TaxID=2052938 RepID=A0A2S0V8X0_9ENTR +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRHIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. Irchel s3a18 TaxID=2009053 RepID=UPI000BA39F7F +---LSRTLTEIETHLNARLGATIIDTESGKVW-SHRADERFPMTSTFKAFACAGLLARID +AGKEDPNRRVVVHEDDLVTYSPVTEQRVGGDMTLSELCEAAMSMSDNTAANIILGTLGGP +DGFTRFMRSLGDDITRLDRWETALNEAMPDDPRDSTTPEAIARSLQELVLGTKLSPSSRQ +QLENWLVGNKVGGPLLRAGLPANWRIADRTGAGGYGSRSIVAVIWPPERKPAVVAIYITE +TEASMDERNAGIAEIGRMLA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKG2_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDMVEYSPVTEKHLTDGMTVRGLCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAEPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas viridiflava TaxID=33069 RepID=UPI000F044B34 +---IQQQLADLEHRHGGRLGVAILNTASQRLI-SHRGDERFALCSTFKCLAAACVLSRVD +QTQEDLARRIAYSAEQLVPYSPTTELHVGGQLSVGSLCEAAMTLSDNTAANVLLDSLGGP +DALTAWLRSIGDTQTRLDRREPELNENRPGDPRDTTTPVAMLHTLNTLVLGSELTLPSRD +QLTAWLVNNQTGDKKLRAGVPAHWRVGDKTGSGANNASNDVAVIWPGDRSPILVTAYYTG +SKASGDQINVLMADIGRLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE53E26 +-dEINRRMEALEKEIGGRIGVSAIDTETSISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP +AELTKWVRTIGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD +KLVEWMVANTTGGARLRAGLPDTWKIGDKTGTANNGSAADIAVLWPPGHGAILVAAYVTQ +AKAPLSEINPVFAEVGKIVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. 174MFSha1.1 TaxID=1502749 RepID=A0A1I7KMR3_9RHIZ +--DAVARLAQLERRDGGMLGVEVRDTATGRRF-GHRADERFPMCSTFKAIAAAAVLARAD +AGKEDLNRRIAFSRDALLSYAPVTTKHVETGMTLAELCGAAVVWSDNTAANLMLDTLGGP +GGITAFARAHGDTVTRLDRTEPTLNTAIAGDVRDTTSPAAMVGLLENVLLGRALSAESRD +RLIGWMHDSPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG +SPAEPAARDALHAEIGRLIARSf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus bacterium TaxID=2053512 RepID=A0A506QPE0_9BACI +-qATHKEFSQLEKKYDARLGLYAIDTGTNEII-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYKKEDLVNYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPVHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIVVILSSK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. HMSC76G11 TaxID=1608910 RepID=A0A1S1FP27_9BACI +----NHDFDKLGEKFDAKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNQRITYTREDLVNYNPITEKHVDTGMTLKELSDASIRYSDNTAANLILKQLGGP +TGFKKALEEIGDNVTNPERYEPDLNEVNPGETHDTSTPRALAASLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR +DKKDADYNDELIAEATKEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF62AE6 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSNERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDILSTEKRN +LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH +DKEDAKYDDKLIAEATQIVLQ-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. ap11 TaxID=1761799 RepID=A0A1H8VK65_9RHIZ +--DAAARLAQLERRDGGRLGVEVRDTATGRRF-GHRADERFPMCSTFKAIAAAAVLARAD +KGQDDLNRRISYGRDDLLSYAPVTSKNVATGMTLAELCAAAVVWSDNTAANLMLATMGGP +AGITAFGRAHGDGVTRLDRTEPTLNTAIAGDPRDTTTPAAMVGLLDNVLLGQALSAESRG +KLVGWMHESPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG +SPAEPAARDTLHAEVGRLIARSf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00032E0E11 +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTI-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDKGMALKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium indicum TaxID=1775910 RepID=A0A147FEF5_9RHIZ +--DAVARLAQFERRDGGRLGVEVRDTATGRRF-GHRADELFPMCSTFKAVAAAAVLARAD +KGQDDLNRRIAYTRDDLLSYAPVTSKHVESGLTLAELCAAAVVWSDNTAANLMLATLGGP +GGITTFARAHGDTVTRLDRTEPTLNTAIPGDPRDTTSPAAMVGLLDNVLLGKALSAESRT +KLVGWMHESPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG +SPAEPAARDALHAEVGRLIARSf +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia strydomiana TaxID=1245417 RepID=A0A4R0X0B9_9BURK +--TIRARLREIEADSGGRLGVAIVDTTSGLHT-GLHADERFPMCSTFKLLVAGAILARVD +RGEEDLQRRIVYSQSELVPNSPATSKHTRERMSVGDLCKAAITLSDNTAANLLLASFGGP +AALTEFARSLGDGITRLDRIEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA +QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIVWPPGRGPILVAVYLTE +TAGDAVRCNAAIASVGALVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter agglomerans TaxID=549 RepID=UPI000F5DBA6E +--TLKSQFETLENKSGGRLGVTVVDTSDGSEY-SWRGNERFPLCSTSKVMAVAAILKKNE +SDHSLLDKKIHINKSDMVNYNPITQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP +QQATHFARTIGDKAFRLDRKEPELNTAIPDDVRDTTTPSAMADTLNKLVLGTALKGEQRA +KLSEWMKGNTTGANSIKAGLPADWIVADKTGSGDYGTTNDIAVIWLKDQAPIILTTYFTQ +KDKDAVARKDVLASAAKLVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=A0A679JI96_VARPD +--SAESQLAELERASGGRLGVTGFDTGTGARI-QHRAHERFPMCSTFKLMLAAAVLERSA +KEPDLLARQLSYGRSDLIANSPITEKHVTTGMRVAELCAATIQYSDNAAANVLLRLLGGP +GEVTAFSRRIGDQVFRLDRTEPELNTSIPGDMRDTTTPSAMSDSVQRLVLGDALGAPQRD +LLKTWLLGNTTSKERFMAGVPAGWKVGDKTGAGSYGSNNDVGVLWPPAGAPLVLSVYLTF +SQKDAKTRNDVVAAATRIAVT-- +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00062CAFD0 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMXTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWNPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI0007ECC635 +---LRAQWAEIERRTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLVQRVKIRASDMLEHAPVTERHVGGLLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. SLFW TaxID=2683259 RepID=UPI001412A41A +--SLQQRLADLEHRHGGRLGVAILDIGSQRLV-SHRGDERFAMCSTFKALAAAHVLARVD +RKEEDLSRLIVYGKDQLVPYSPTTEKHTGEALSVGSICEAAVTLSDNTAANLLLDSFGGP +AGLTQWLRWTGDEVTRLDRREPELNENRAGDPQDTTSPIAMLQTLRSLIFGDVLTGASRD +QLIAWLVSNTTGDKKLRAGLPKKWRVGDKTGSNAKNADNDVAVIWPSSRAPLIVTVYYSE +SRANAEQVNAVMADIGRIVAE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=J8HJS9_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKDATYDNKLIADAAEVIVK-- +>[subseq from] Carbapenemase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0A8P2Z6_ECOLX +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPRSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB33FA +--DVEARLAELEKRTGGRLGVSVLDTATNISF-GCREDERFAMCSSFKALAAGFILARVD +QGAETLDRRIVVAQKDIIAHSPVTEKHLGGEMTIADLCAATMTTSDNAAANLLLESFGGP +SALTAWLRMIGDETTRLDRNEPTLNEAKKGDPRDTTTPAAMLETLGNLAFGPALTADSRK +RLIEWMVANTTGDERIRAGLPKGWKVGDKTGTNATGSASDIAVVWPEGRAPLLIAVYIAE +ATAPLSVLNTVFADVGRVAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium laguerreae TaxID=1076926 RepID=UPI001441830A +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARTD +KGEENLGRRVSYGRDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKSDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0013DA0307 +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARGD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTFGNLTLGSVLTEASCD +KLIAWLVASATGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. ERR 942 TaxID=2572676 RepID=A0A560LPX8_9RHIZ +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKEDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATADAKDVEAVFAEVSKIIVD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium multihospitium TaxID=410764 RepID=A0A1C3V044_9RHIZ +--DVDKQLVDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAAGFVLARVD +QGTEKLDRRITYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDTIGLLTLGNTLSETSRD +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAAAKDVEAVFAEVSKIIVD-- +>[subseq from] Beta-lactamase n=2 Tax=Rhizobium TaxID=379 RepID=A0A4R3R406_9RHIZ +-dDIERRLGELEKRTGGRLGVSVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD +KGEENLERRVIYDRDKLVSYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLLLESVGGP +KALTKWLRSIGDRATRLDRWETALNEGKKGDPRDTTTPDAMLDTLGNVALGSVLSEPSRE +KLIAWMLANTTGNARLRAGLPGDWKVGDKTGTGDNGSAADIAIIWPKGRGPVLVTAYIAE +ARAPVKELNLVFVEVAKIVA--- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000667C644 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHXRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Chromobacterium sp. ATCC 53434 TaxID=2059672 RepID=A0A2H5DZ93_9NEIS +---AAETFAKIEKDFGGTIGVHAIDTGSGAVV-SYRAEERFPLCSSFKGFVAAATLARSQ +QQAGLLDKRIAYGEDALISWSPITRKHQATGMTVAGLCAATVQYSDNAAGNLLLKELGGP +AGLTAFMRSIGDRTFRLDRWEPELNTAIPDDARDTSSPRAVAESLRKLALGSALAAPQRR +QLNDWLKGNTTGDKRIRAEVPAGWKVGDKTGTCGYGTANDYAVIWPKGRAPIVLAVYTKG +RDKNLKPSDAVIAAAAKAALE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BAE7F87 +-qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMEDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00141B0FA7 +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAVAVR--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8RPD3_BACCE +---THREFVQLEKKFDARIGVYAIDTGTNRTV-AYRPDERFAYTSTFKALAAGAVLQQNS +--IDQLNKVITYTKDDLVTYSPITEKHLDTGMTLWEIADAAIRYSDNTAGNLLFKELDGP +KGFEKKLRQIGDRVTKVNRFEPDLNEATPGDIRDTSTAKALATNLKAFTVDNVLPTDKRK +ILTDWMRGNTTGDQLIRAGVPKDWEVGDKTGAGSYGTRNDIAIVWPPNREPIIIAILSSR +DTKNATYNNELIAQAAKVTIN-- +>[subseq from] Beta-lactamase n=1 Tax=Providencia stuartii TaxID=588 RepID=O68473_PROST +--ETLVKVKDAEDKLGARVGYIELDPNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMRTTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRCALPAGWLIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Kluyvera sp. Nf5 TaxID=2116543 RepID=UPI000D178FD7 +-----ETVKKAEDQLNARVGYAELSLSNGQMLgSYRPQERFPMMSTFKVLLCGAVLSRVD +AGQEQLARRIQYRKQDLVAYSPVTEKHLTDRMTVAELCSAAITMSDNTAGNLLLSAIGGP +SELTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQMLRQLLNGKILTPASQQ +QLMAWMEADKVGGPLIRSVMPAGWFIADKTGAGERGSRGIVAALGPDGKPARIVVIYITE +TQATMDERNKKIADIGASLIKHw +>[subseq from] Class A beta-lactamase n=1 Tax=Sinorhizobium sp. A49 TaxID=1945861 RepID=A0A1V3QQX0_9RHIZ +--DVDARLAELEKRTGGRLGVSVLDMDTNISF-GCREDERFAMCSSFKTLAAGFILARAD +QGAEKLDRRLVVAQKDIIAHSPITEKHVGGEMTIADLCAATMTTSDNAAANLLLESFGGP +QALTAWLRTIGDDTTRLDRNEPTLNEAKMGDPRDTTTPAAMLETLGNLAFGPALTEPSRK +LLIEWMVANTTGDQRIRAGLPKGWKVGDKTGTNSTGSASDIAIVWPEGRGPLLIAVYIAE +ATAPLAELNTVFADVGRMAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SN10 TaxID=2056493 RepID=A0A2N1JYT8_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQYS +--TEKLNDVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRYSDNTAGNILFHQIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSNK +DEKGATYDNQLIAEAAGVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF91C1B +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKTLATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. Irchel s3b6 TaxID=2009078 RepID=UPI000BA444D0 +---LSRTLTEIETHLNARLGATIIDTESGKVW-SHRADERFPMTSTFKAFACAGLLARID +AGKEDPNRRVVVHEDDLVTYSPVTEQRVGGDMTLSELCEAAMSMSDNTAANIILGTLGGP +DGFTRFMRSLGDDITRLDRWETALNEAMPDDPRDSTTPEAIARSLQELVLGTKLSPSSRQ +QLENWLVGNKVGGPLLRAGLPANWRIADRTGAGGYGSRSIVAVIWPPERKPAVVAIYITE +TDASMDERNAGIAEIGRMLA--- +>[subseq from] Beta-lactamase n=1 Tax=Hydrogenophaga sp. LA-38 TaxID=2294117 RepID=A0A372ELX0_9BURK +--ALDAAARALEAKSRGRLGVHILDTADGREW-GHRSDERFLMLSTFKTLAAALVLRRAD +QGKAPLSKRVRYRQRDLVQWSPVTEKHVGGRLSLAQLCEATITTSDNTAANLILREVGGP +AALTAFLRGVGDPVTRLDRMEPELNEPSPGEDLDTTTPRAMARTLRTLLLGEALSPASRE +QLAAWLKANTTGDRRLRAGVPPSWGIGEKTGTAGE-SANDAGIVWPPGRAPLLVSAYLAD +SPAGAAAREQALAGVGRLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Hydrogenophaga sp. 70-12 TaxID=1895769 RepID=A0A1Q3QHQ4_9BURK +--ALDAAARALEAKSRGRLGVHILDTADGREW-GHRSDERFLMLSTFKTLAAALVLRRTD +QGKAPLSKRVRYRQRDLVQWSPVTEKHVGGRLSLAQLCEATITTSDNTAANLILREVGGP +SALTAFLRGIGDPVTRLDRMEPELNEPSPGEDLDTTTPRAMARTLRTLLLGDALSPASRE +QLAAWLKANTTGDRRLRAGVPPSWGIGEKTGTAGE-SANDAGIVWPPGRAPLLVSAYLAD +SPAGAAAREQALAGVGRLLA--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2A7D9T1_BACAN +--TVNHPFSKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFGLGDVLSTDKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDANYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium mesoamericanum TaxID=1079800 RepID=UPI000421354C +--DINRRMDALEKAIGGHIGVSAIDTDTNISF-GYRETERFPICSTFKVLAAGLVLARVD +KGQETLERRVVYEKDKLVTYSPETEKHVGGEMSLSELCQAAITLSDNTAGNLLLESFGGP +AELTKWLRTLGDRSTRLDRWETALNEVKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD +KLIEWMVANTTGGARLRAGLPDTWKIGDKTGTANNGSAADIAVVWPPGHGAILVAVYVTQ +AKAPVSEINPVFAEVGKVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium hidalgonense TaxID=1538159 RepID=UPI000FEC8014 +-dNVEKRLAALEKRTGGRLGVSVLDTETSISF-NYRGSEAFPMCSTFKALAAGFVLARVD +KGEEKLDRRVTYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTSPDAMLDTLGNLTLGSILTEASCD +RLIAWLVASTTGGERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATVPVKDLNPVFAEVGKMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. JKLM19E TaxID=2583232 RepID=A0A5R9N1R3_9RHIZ +-dNVEKRLAALEKRTGGRLGVSVLDTETSISF-NYRGSEAFPMCSTFKALAAGFVLARVD +KGEEKLDRRVTYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTSPDAMLDTLGNLTLGSILTEASCD +RLIAWLVASTTGGERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATVPVKDLNPVFAEVGKMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. trifolii WSM597 TaxID=754764 RepID=I9N6U1_RHILT +-dDIQKRLAALEKRTGGRLGVSVLDTGTSISF-NYRGSEAFPMCSTFKALAAGFVLARAD +KGEESLDRRVTYGKDKLVDYSPLSEKHADADMTITELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASAD +RLIAWLVASTTGGERLRAGLPSEWKVGDKTGTGPNGSLGDIAVIWPPNRGPIVAAVYIAE +ATAPVKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDA8373 +-nDIEKQLAALEKRTGGRLGVFVLDTKNNVSF-AHRPDERFAMCSTFKALAAAFVLARAD +MGEEKLDRRVPVLKKDLLSYSPVVEKHVGGGMTVRELCDAAVTYSDNAAANLLLASFGGP +KGLTTWLRSIGDETTRLDRTEPELNEAKVGDPRDTTTPMAMTQTLGRLLLQDVLSPSSRD +QFTAWLVANTTGDRRLRAGLPQDWTIGEKTGTSGRGEAGDIGFMRPREGHTILASVYIAE +GKKPTKELEPVFAEVGKLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Methylibium sp. YR605 TaxID=1500265 RepID=UPI0006461962 +------RWAAIEADSGGRLGIAVLDTGTGRFD-GHRLDERFPMCSTFKLLAASLALQRVD +AGLERLDRRVAVRRGMLINHSPVSEKHVGDHMSIAELCEAAVVVSDNAAANLLLASFGGP +AAITRYARTLGDTQTRLDRTEPALNEARPGDPRDTTTPRSMAIALQSALLGSALSDASRA +RLVAWMEAVRTGTDRLRAGLPPGWRVADKTGTGARGSTNDVAVVWPPNRAPLVITAYLTD +SKADAKRLNAALAAVAREAAGRf +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI00128D9D3A +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +NAATMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000987BC53 +-qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSNK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0009BDFCE2 +-qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSNK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. ABP14 TaxID=1892404 RepID=UPI0011A18FF3 +--TVNHPFSKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFGLGDVLSTDKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDANYDDKLIAEATKIVLD-- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000D746BE6 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009E2D11E +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVDYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0A1ISX2_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus nitrificans TaxID=651560 RepID=A0A3M8DKN6_9BACL +--ALDPQFGQLEKDFGARLGVYAIDTGSGREI-TYRGEERFAFASTFKALAAGAVLKQST +--DEQLHVVINYTSDDLVTYSPVTEKHVQTGMTLSEISEAAIRYSDNTAGNLLLKQLGGP +EGFEKILRELGDQVTSPVRYETELNEAIPGDTRDTSTPKALAGTLQKLTLGDVLPQEKRS +MLINWMLGNETGDKLIRAGAPKDWVVADKSGAGSYGTRNDIAVIWPANGDPIVMAILSST +DKQDAPYDNALIEKAAKVALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas viridiflava TaxID=33069 RepID=UPI000F03E51A +---IQQQLADLEHRHGGRLGVAILDTASQRLI-SHRGDERFALCSTFKCLAAACVLSRVD +QKQEDLARRIVYSAEQLVPYSPTTELHVGGQLSVGSLCEAAMTLSDNTAANVLLDSLGGP +DALTAWLRSIGDTQTRLDRREPELNENRPGDPRDTTTPVAMLHTLDTLVLGSELTLPSRD +QLTAWLVNNQTGDKKLRAGVPAHWRVGDKTGSGANNGSNDVAVIWPGDRSPILVTAYYTG +SKASGDQINVLMADIGRLVA--- +>[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=UPI000CF30E09 +heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD +TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP +LGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ +QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA +TPASMDERNKQIAAIGETLVRHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00102FE186 +--NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVTHGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAVLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMVVE-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000D6FDF39 +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAVIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Ensifer adhaerens TaxID=106592 RepID=UPI000CF037DA +--DIDRRLAELEGRTGGRLGVSVLDTQTNISF-GRRENERFAMCSSFKALAAGFILARVD +QGTETLDRRIPFQEKDLVTYSPVTEKHVGGAMTIAELCAATITTSDNTAANLLLDSFGGP +SALTAWLRSIGDENTRLDRIEPALNEAKKGDPRDTTTPAAMLDTLGKLTVGSALTESSRK +QLNAWMVANTTGDLRIRAGLPAAWRVGDKTGTNATGEASDIAIVWPEGRSPLLITVYIAE +ATAEVKDLNPIFAEVGRMAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Proteus sp. FJ2001126-3 TaxID=2050966 RepID=UPI000D6921A0 +-nTIEEQLSTLEKYGKGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVATVLKESE +KQAGLLDKNITIKKSDLVVYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP +AKVTQFARSINDVTYRLDRKEPELNTALHGDPRDTTSPIAMAKSLQALTLGDALGLSQRQ +QLVTWLQGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEKDAKYRKDIIAKAAEIVTKPf +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. BK460 TaxID=2512152 RepID=A0A4Q7LFI8_9BURK +--SAETQLAALESASGGRLGVVGLHTGSGARI-QHRAHERFPLCSTFKLMLAAAVLERST +QDGGLLSRNLSYGKIDLIAHSPVTEKHVATGMTVGALCAATIQYSDNAAANVLLKMLGGP +AAVTAFARRIGDQAFRLDRTEPELNTSIPGDLRDTTTPAAMTDSVQRLALGDALPTVQRD +QLRTWLLGNTTSTERFLAGVPAGWKVGDKTGAGSYGSTNDVGVLWPPAGAPIVLSVYLTF +PQKDAKGRNDVIASATRIAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus anthracis TaxID=1392 RepID=A0A2B8I2G5_BACAN +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVQKRN +ILTEWMKGNATGDKLIRAGVPTNWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DDNGATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000B4AFA1C +-----DSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYNREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIALD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. MHM7A TaxID=2583233 RepID=A0A5R9NNT0_9RHIZ +--NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKAPAAGFVLARVD +KGDEKLDRRVTYGRDKLVDYSPLSEKHAGVDMTIAELCEAAVTVSDNTAGNLLLESFGGP +PALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASSTGKERLRAGLPQDWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVKDLNPIFAEVSKMITE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=UPI00064FEB97 +--DLDETFATIESDYDARVGVYAIDTGSDQTI-EYRSEERFAFASTYKALAAALVLKQNS +--MEELEEVITYTEDDLVSYSPITEKHVDTGMTLAELSEAAVRTSDNTAGNLLFEELGGP +EQFQQSLREIGDDVTQSDRYETALNEFTPGNTRDTSTPAALATSLQGFAVGDLLTDDKRE +LLLDWMQGNATGDTLIRAGAPEGWTVADKSGAGRYGTRNDIAVVWPPDREPIILAIMTRH +DTEDAEYDDALIAEVAEATLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000B43A680 +----NNSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--TEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVNPGETHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKE7_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWIEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium phaseoli Ch24-10 TaxID=1128399 RepID=A0A0M3GLP2_9RHIZ +--NVERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD +KGDESLDRRVTYGKEKLVDYSPTSEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +KLIAWLVASTTGKERLRAGLLADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATTPAKDLNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF8348B +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYKKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +NGYEKALRQLGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAQKSK +ILTEWMKGNATGDKLIRAGVPTDWVVVDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVVVNDf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKD0_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYLPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium terrae TaxID=2202827 RepID=A0A2U8WQH1_9RHIZ +--DAAAKLAQLERRDGGRLGVEVRDTATGRRF-GHRADERFPMCSTFKAIAAAAVLARAD +KGQDDLDRRIAYGRDALLSYAPVTSKNVETGMTLAELCAAAVVWSDNTAANLMLDTMGGP +EGITTFARAHGDTVTRLDRTEPTLNTAIPGDVRDTTSPAAMVGLLDNVLLGNALSAGSRA +RLTGWMHESPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG +SPAEPAARDALHAEVGRLIAR-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. NFR17 TaxID=1566260 RepID=A0A329ALZ8_9RHIZ +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAAGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRE +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE +ATAPAKDVEAVFAEIGKIVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL23I1N1 TaxID=1938802 RepID=A0A419ZZV6_9BURK +--AIRQRLAQIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKLLAAGFVLTRVD +HGQENLERRVVFSNSDLVPYSPATSQHTRERMSVADLCKAAITLSDNTAANLLLASFGGP +VALTAFARCIGDGITRLDRNEPTLNAATPGDPRDTTTPNAMLGNLRELLLGERLSASSRA +QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVAVYLTE +TSGDAARCNAAIANVGALVA--- +>[subseq from] Beta-lactamase n=2 Tax=Acidovorax citrulli TaxID=80869 RepID=A0A481SPD1_ACIAI +---FARAVQEVEASVGGRLGVALLDMATGRQD-AHRGDERFPLCSTFKLLLAAHVLRRVD +QGHERLDRRISYRKSDLVEYSPATERHADGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP +LELTAWLRSLGDTQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSAAARA +RMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDAGLFWPPDRGAVMVSCYLTG +SPAPAEQRDAAIARVGTLAA--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI00059D4CD3 +-qATHKEFSQLEKKFDARLGLYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=I6ZG87_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIA---------- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium etli (strain CFN 42 / ATCC 51251) TaxID=347834 RepID=Q2KAW1_RHIEC +--NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGEENLERRVTYGRDKLVDHSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTSPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATASVKDLNSIFAEVGKMITE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0B4ZZ63_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIA---------- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI001033A462 +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATIAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Pseudomonas TaxID=2583993 RepID=UPI000CD0915F +--ELYKKLAELENSAKGRLGVALINTANGHEI-QYRGGERFPFCSTFKLMLAAAVLHKSM +AEPGLLEKHIAYAEADLLSYAPIAKQNLEQGMSIAQLCAATLQYSDNTAANLLIKELGGV +AAVNLFAKGLGDPAFRLDRQEPELNTAIPEDPRDTTTPAAMAASVQKVVLGDALATAQRE +QLATWLKGNTTGDASIRAGTPTGWIVGDKTGSGDYGTTNDVAVLWPQTGAPVVLAVYFTQ +HQKDAEARRDVLASATRLVMAH- +>[subseq from] Beta-lactamase n=1 Tax=Legionella erythra TaxID=448 RepID=A0A0W0TKI6_LEGER +--SLQQKLAALEASNGGRLGIAAINQANGMVI-QYHARQRFPLCSTSKAISVAALLRKSM +NDKTLLHEKIHYNKQDLVVHSPETEKHLADGMTLAELSEATITLSDNTALNLILKKLGGP +QAITAFARSIGDNEFRLDRFEPELNTAIPGDARDTTTPKAMALSLQKLITTDTLASPERQ +LLITWLRNNTTGGARIRAGLPEGWVVGDKTGTGDYGTSNDIGVIWPPHCQPVTLVVYFTQ +PKVDARPNNEVIAAATRIVISAf +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AF3DCF +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +VLTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAAYDNQLIAEATEVIVK-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0011DC87D7 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR +QLLQGMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A2B4XCQ7_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAAYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q2XT35_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALLAGWFIADKSGAGERGSLGIIEALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKF9_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNAAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDEHDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00063E91CD +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGKLTLAQQVKIRASDMLEHAPVTERHVGESLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGETCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000C9B153D +-----EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALI--- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815) TaxID=391038 RepID=B2JHB5_PARP8 +--ALDKRFAQIEAETGGRLGVAILDTANGQLQ-GWRARERFPMCSTFKFLLASAVLMRKD +QGKEQLGRRIVYAKDAVVANSPVSGPRAGGDMTVSELCEAALTRSDNTAANLLLESIGGP +PALTVFARGIGDGVTRLDRNEPTLNEAIEGDPRDTTTPAAMIADMRAMLLGEHLSAASRQ +HLTVWLVANKTGDTRLRAGLPPDWRVGDKTGTGERGTSNDIAIVWPAGRPPVLVAVYLTG +ATTSAAQRDAAIAKVGALVA--- +>[subseq from] Beta-lactamase n=2 Tax=Rhizobium TaxID=379 RepID=A0A4R0B1Y1_RHILV +-dNIQKRLAALEKRTGGRLGVSVLDTDTSISF-NYRGSEAFPMCSTFKALAAGFVLARAD +KGEESLDRRVTYGKDKLVDYSPLSEKHAGADMTVAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLSESSAD +RLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVATVYIAE +ASVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium 13_2_20CM_2_54_15_9cls TaxID=1805418 RepID=A0A1Q6WYY9_9BACT +--DAADQIAAIEARLGGRIGVAGLDTGNGKRI-DYRAEERFPLCSTFKFLAAAAVLKRVD +EKKDKLDRFVSYDAKDILEYAPVTKAHLGNGMTLGALCAAAIEQSDNTGGNLLLEAIGGP +VGLTNFARDLGDRMTRLDRKEPELNSAIPGDDRDTTTPASMLGDIRQLLVGNTLSASSRQ +QLQEWLQANETGAAMIRAGIPTNWIVGDKTGRGANGATNDVAIVHPPDRAPIVLAIYCVG +STASANDRAAAVAEAAKVVAESf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDC0BD8 +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD +QGAEKLDRRITYGKDKVVTYSPETEKHAGGDMTIAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAAKGDPRDTTTPDAMLDSIGLLTLGNTLSDTSRE +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVATFVAE +ATAPAKDVEAVFAEIGKIVV--- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6BGI3_9BACT +--DVADRIAAIEGRIGCRIGVAALDTGNRKRL-DYRADERFPMCSTFKFLAAAAVLKRVD +EKQEKLERFVPYDAKEILEYAPVTKEHLKDGMTLGALCEAAIEQSDNTAGNLLLDAIGGP +AGLTNFARDLGDRITRLDRKEPDLNSAIPGDERDTTTPGSMLGEMTRLLTGDVLSQLSRR +QLEDWLQGNKTGAAMIRAGIPANWIIGDKTGRGANGATNDIAIMHPPGRAPILLAIYSVG +STATADDRAAAIAEAAKIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL18I3N2 TaxID=1938799 RepID=A0A2T0L7G1_9BURK +--AIRRRLAEIEAASGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKMLVAGAVLARTD +RGEENLQRRVVFSQSDVVSNSPATGKHARELMSVAELCKAAITLSDNTAANLLLATFGGP +AGLTAFARSLGDGVTRLDRIEPTLNEGTPGDPRDTTTPNAMLGNLRELLLGERLSSSSRA +QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPVLVTVYLTG +TDGDAARSNAAIADVGALVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDBE0FB +-dDVDQQLAALEKRTGGRLGVSVMDTGTNVSF-SNRETERFPLLSTFKVLAAGMVLARVD +GGDENLERRVTYDQEKIVTYSPETEKHVGAEMTVGELCKAAITLSDNTAGNLLLDSLGGP +EALTKWLRSIGDTSSRLDRIETELNEAKKDDPRDTTTPDAMLHTLGNLALGTVLSEPSRQ +QLIDWMTANTTGAARLRAGLPEEWKVGDKTGTGSNGSAADIAIIWPEESSPILVAVYVAE +ANAPVSELNDVFAEVAKLAA--- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella sp. K-Nf6 TaxID=2054595 RepID=UPI000C2898B9 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSDKHLVDGMTIGELCAAAITMSDNSAGNLLLATVGGP +VGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGNAERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000D0195C0 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--KEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000CDB5715 +----NHNFAKLEEEYDVKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEELNQRITYTREDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILKQLGGP +TGFKKALEEMGDDVTNPERFEPDLNEVHPGETHDTSTPKALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR +DKKDADYNDNLIAEATKEVIK-- +>[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=Q2YHY3_KLEPN +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFD078E +hqATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK +VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAVLSSK +EEKEATYDNQLIAEAAEMIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0003E2CB53 +-dNVEKRLAALEKRTGGRLGVSVLDTETSISF-NYRGSEAFPMCSTFKALAAGFVLARVD +KGEEKLDRRVTYGKDKLVDYSPFSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTSPDAMLDTLGNLTLGSILTEASCD +RLIAWLVASTTGGERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATVPVKDLNPVFAEVGKMIVE-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000E2DC9C4 +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDHWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Sorangium cellulosum TaxID=56 RepID=UPI0009D72648 +---TAPALARIEAQLGGRLGVAALDTANGARI-GHRAGERFAMCSTFKSLLAACVLARVD +QGQLTLDRRIAYRESDLLEHAPVARARLAEGLTVEELCAAAVEVSDNTAANLLLAQIGGP +AGLTAYLRGLGDQVTRLDRDEPALNTNLPGDPRDTSTPDAMTDTYRSLLVGDALREASRA +RLKAWMVRATTGLARLRAGLPRDWVVGDKTGTGENGIANDVAVAWPPSRAPIVVACFVEA +PSASVDARNAAHAEVARLVAAAf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI0008F58539 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNP +--IEKLNDVIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR +FTKDAEYDNALIAEAAKVALD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium aethiopicum TaxID=1138170 RepID=A0A1C3Y8T1_9RHIZ +--NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGGEAFPMCSTFKALAAGFVLARVD +KGDEKLDRRVTYGRDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +PALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +KLIAWLVASTTGGERLRASLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATVPAKELNPIFAEIGKMIVE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B51C55 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIADAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00103F8875 +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFSMCSTFKALAAAFVLARAD +KGEENLDRPVSYGKDRLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI0009A9C9D9 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +PGLTAFIRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLA---- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sediminicola TaxID=458836 RepID=A0A495H0X1_9BURK +--AIRQRLAQIEVESGGRLGVSILDTTSGLHA-GLRTDERFPMCSTFKLLAAGLVLTRVD +HGQEDLERRVVFSKSDLVPYSPATSQHTRERMSVADLCKAALTLSDNTAANLLLASFGGP +AALTAFARSIGDGITRLDRNEPTLNEATPGDPRDTTTPSAMLGNLRELLLGERLSSLSRA +QLLAWLAANRTGGERIRAKLPKDWGVGDKTGTGDHGTANDIAILWPPGRGPILVTVYLTE +TSGDAARCNAAIASVGALVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF2C7B1 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia ignorata TaxID=145285 RepID=UPI00082D37C6 +-----TQFAALESKYTARLGLSVTDTGTGATV-AYRADERFPIASTFKGLACGALLQAHP +LSTGYFDQVIHYTAADLVEYSPETEKHVDTGMTVAALCHATITLSDNTAGNLVLRLLGGP +AGFTAFLRTLGDNVTRLDRWETELNTAIPGDERDTTTPAALAADYRALVLGDVLAEPERT +QLADWLKANTTGGKRIKAGLPTDWTVGDKTGSPAYGSALDVAIAWPPNRPPLVLAVLSTK +SEQDAEPSNELLAEATKAAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Methyloceanibacter marginalis TaxID=1774971 RepID=A0A1E3W8X7_9RHIZ +-kSLEQTFAAIEAKVGGRLGVAAYDTGSGLKA-AWRGDERFPLCSTFKWLAGAAILARVD +QGKETLKRKVPIRAEEIVTYSPATEKHVGETMPLEQICEAAIALSDNTAGNLMLAALGGP +EGFNAYVRSLGDGVTHLDRIEPALNEAAPEDPRDTTTPLAMIADLDAALVGDALSRASRN +KLTAWLIGNETGDARLRAGLPENWRVGDKTGTCNARTANDVAIAWPPSGKPVLIAVYLAE +SDVSPEAQNKAIADVARAVAT-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKJ0_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLFRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTAIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDGRDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D624_KLEPN +-----EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000C77DB24 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS +--NEKLNDIIRYTKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=A0A5S4Z009_9BACI +--DLDETFATIESEYDARVGVYAIDTGSDQTI-DYRSEERFAFASTYKALAAALVLKQNT +--MEELEEVITYTEDDLVSYSPITEKHVDTGMTLAELSEAAIRTSDNTAGNLLFEELGGP +EQFQQSLREIGDDVTQSDRYETALNEFTPGNTRDTSTPAALAMSLQGFAVGDLLTDDKRE +RLLDWMQGNATGDTLIRAGAPEGWTVADKSGAGRYGTRNDIAVVWPPDREPIILAIMTRH +DTEDAEYDDALIAEVAEATLN-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. trifolii WSM1689 TaxID=754523 RepID=W0IAJ4_RHILT +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARTD +KGEENLDRPVSYGRDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPADRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000E4EE96E +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ +LLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI07_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAK----------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A0B5S764_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0005CDCEDA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMGTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRYYGELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0A7HG88_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSPNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000E2CC11A +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWEMALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKG3_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLPLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF686AA +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKNS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVVAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI001034683A +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQHDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-46 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5B8WEV9_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELEPNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Sorangium cellulosum TaxID=56 RepID=A0A4P2QKS1_SORCE +---AAPALARIEAQLGGRVGVAALDTATGARV-GHRAAERFAMCSTFKALLAACVLARVD +QGQLRLDHRVTYRESDLLEHAPVTRARVAEGLTVEDLCAAVIEISDNTAANLLLAQIGGP +AGLTAYLRGLGDEVTRLDRNEPALNENVPGDPRDTTTPDAMTDTARAILIGDALQRASRE +RLASWMVRSTTGLARLRAGLPKDWIVGDKTGTGM-GIANDVAVAWRPSRAPIVIACFVDA +PSASADARNAAHADVARVVAEAf +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A1Q4LKB6_BACCE +---TYKDFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKAIAAGVLLQKNS +--TEKLNEVITYTKEDLVDYSPVTEKHVGTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQIGDMVTLSDRFETELNEAIPGDNRDTSTAKAIATNLKDFTVGNALSDDKRN +ILTDWMRGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Prosthecobacter debontii TaxID=48467 RepID=A0A1T4YQW7_9BACT +--SAHRQLAELEFESQGRLGIAAWTASSRRSV-RYRPNERFPFCSTFKFLAAAAILKRTE +QDPTELDRHIRYSKQDLVSYSPITEKQAGRSMSLAQLCAAALQYSDNTAGNLLIKELGGT +QAMTAFARSIGDSTFRLDRWETELNTAIPGDVRDITSPAAMAHDLQRLLLGHGLSPQQRN +QLSTWMRGNTTGAARIRAAVPSDWEVADKTGSGDYGTTNDIGILFPPNQSPIILAIYFTQ +KTSQAPMRNDIIAAATKIVLE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1Q9HYG7_BACCE +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000BB85D27 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVXGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQI----------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKH1_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWVEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEC8266 +--TVNHSFAKLEKEFDAKLGIYALDTDTNQIV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN +LLIVWMKRNTTGDKLIRAGVPRGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Trinickia caryophylli TaxID=28094 RepID=A0A1X7FSF0_TRICW +--DAAQALAALERISGGRLGLCAIDTARGATL-GYRASERFPFCSTFKLMLAATVLARSV +EEPALLEHRIRYARTDLVNYSPETGKHVDDGMTVSELCRVTVQWSDNTAANLLIDLLGGS +QAVTAYARGIGDREFRLDRRETTLNTAIPGDLRDTTTPAAMAQSTRSLVLGSALPAPQQA +RLRDWLLGCKTGDRRIRAAVPAGWQVGDKTGTGDYGTANDVGVLWPPAEKPLVLAIYHTH +TDSAAKARDDVIASAARIAIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI0006CAD317 +---LRAQWAEIERGTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Phytobacter palmae TaxID=1855371 RepID=UPI0008ECB3FF +--VTQETVKKAEDQLNARVGYAEVALANGQILgSYRPQERFPMLSTFKVLLCGAILSRVD +AGQEQLARRIRYRQQDLVEYSPVTEKHLTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP +SELTAFLRKAGDQVTRLDRWETALNEALPGDERDTTTPEAMAQILRQLLTGKILTPASQK +QLIAWMEADKVGGPLIRSVLPSGWYIADKTGAGGRGSRGIVAALGPDGKPTRIVVIYITG +TQATMDERNKKIADIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. DE0042 TaxID=2584950 RepID=UPI0011AA81B5 +--TVNHSFSKLEKEFDVKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPEHFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS +LLIDWMKRNTTGDNLIRAGVPRGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Chromobacterium sp. LK1 TaxID=1628193 RepID=A0A0J6K8B5_9NEIS +----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPMCSSFKGFLAAGVLAQSQ +AKPGLLDKRIRYSKTTLPNWSPLTTQHQANGMTVAELSAATVQYSDNGAANLLLKEINGP +AALTAFMRSIGDTTFRLDRLEPELNSAIPGDPRDTSTPKAVAESMQKLALGKALAAPQRQ +QLADWLKGNTTGKARIRAAVPDGWEVGDKTGTCGYGTANDYAVIWPPKRAPIVLAVYTKH +AKKEAKHSDEVIAAAARAALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEE17E0 +---LRAQWAEIERRTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLVQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLADWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPSAGAPLLLAAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFA86C5 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Roseomonas mucosa TaxID=207340 RepID=A0A4Y1MSQ5_9PROT +-----AVFAGIERRVGGRLGVAVLDTATGQRA-GHREAERFPLTSTFKLLAAAAVLSRVD +AGQARLDQRIRYGREKLVAYSPETEKHAGEEMTLAAICEAAVTLSDNTAGNLMLEQIGGP +AGLTAWLRSIGDTVTRLDRWETALNEAEPGDPRDTTSPAAMLASLQRVTLGEALSVGGQA +HLTGWLRANKTGDKRLRAGLPGGWQAGDKTGAGERGTNNDAGLLWPPGEAPILVAAYSTG +STAPSTERDAALAEVAAAIVA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q84H47_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQQIAGIGAAL---- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A387A347_BACTU +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A2B5PYY6_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF53E98 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELAAASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. DHF22 TaxID=2571748 RepID=UPI0013172108 +-sALEQQLAAIESQAGGRLGVAILDTANGRVE-GWRLHERFPMCSTFKVLLASAVLTRKD +RGEEDLARKIAYTQAQVVSYSPVSGPRAGSDMTVAELCEAALTRSDNTAANLLLDSLGGP +AAITAFARGLGDPHTRLDRNETTLNEALEHDPRDTTTPAAYIADMRELLLGERLTQASRE +QLIAWLVANQTGDARLRAGLPKDWRVGDKTGTGDRGTANDVAIVWPPNRAPLLVTAYLTG +ALATPAQRDATLAKVGALVA--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia ignorata TaxID=145285 RepID=A0A4R6PV82_9NOCA +-----TQFAALESKYTARLGLSVTDTGTGATV-AYRADERFPIASTFKGLACGALLQAHP +LSTGYFDQVIHYTAADLVEYSPETEKHVDTGMTVAALCHATITLSDNTAGNLVLRLLGGP +AGFTAFLRTLGDNVTRLDRWETELNTAIPGDERDTTTPAALAADYRALVLGDVLAEPERT +QLADWLKANTTGGKRIKAGLPTDWTVGDKTGSPAYGSALDVAIAWPPNRPPLVLAVLSTK +SEQDAEPSNELLAEATKAAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDDC002 +-dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +KGDESLDRRITYGKDKLVTYSPETEKHAGGDMTMAEICKAAITLSDNTAGNLMLESFGGP +AALTDWLRSIGDGTTRLDRMETTLNEATKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN +QLIDWMIANTTGGARLRAGLPGDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYIGE +ATVKMDEFNPVFAEIGKMITE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. MYb209 TaxID=1848605 RepID=A0A2S8UU15_9BACI +-----HSFVQLEKEYDAKLGIYALDTGTSQTV-TYRSDERFAYASTHKVLAVGALLQKNS +--IEALDQRIKYTSEDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQTYALGDILSTEKRN +FLIDLMKRNTTGDNLIRAGVPREWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLVILSNH +AKEDAKHDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A2A7Z4F9_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIADAAEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A7IXD9_BACCE +---TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQKNS +--TEKLNEVVTYTKEDLVDYSPVTEKYVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDNRDTSTAKAIATNLKDFTVGNALPDQKRN +ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIITILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase CRH-1 n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A5S9EKA3_9NEIS +----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPMCSSFKGFLAAGVLAQSQ +DKPGLLDKRIRYSKAALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLKEINGP +AALTAFMRSIGDASFRLDRREPELNSAIPGDPRDTSTPKAVAESAQKLALGKALPEPQRQ +QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH +AKKEAKHSDEVIAAAARAALEAf +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CED9528 +---LRAQWAEIERRTGGRLGISLLDSATGRHL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPSAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI26_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PQQDAK----------------- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007CBEB2E +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAELPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMVERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI00099508CE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKJ8_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIRYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIITALGPDSKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=2 Tax=Viridibacillus sp. OK051 TaxID=1884360 RepID=A0A2N0F505_9BACL +--TTMEKFEQLEKEYDARLGVYAIDTGTKKTV-EFREDERFAYTSTFKALAAGAVLQQNS +--IEELNKIVTYTSDDLVTYSPITEKYVDTGMTLKEISEAAIRYSDNTAGNLLFKELGGP +EGFETSLKKLGDQVTNAERIETGLNEAVPGETRDTSTPKALANDLQAYTLGDVLTHEKQT +MLVDWLKRNTTGDNLIRAGVPKGWEVGDKTGGGGYGTRNDIAIVWPPNREPIVLAILSSR +DKQDATYNDELIAQATKVVMNVf +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A486UH21_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora siamensis TaxID=299152 RepID=A0A1C5I8Q1_9ACTN +----EHEFRQLEERFDARLGVYAIDTGTGRTV-QYRADDRFAYASTFKALAAAEVLDETT +--DAELDRVVRYSADDLVTYSPITGRHVDEGMTLRAIADAAVRYSDNTAGNLMLRQLGGP +QKFEKELREVGDKVTDPARWETALNEARPGDRRDTSTPRAMAGSLRAYAVGDALEPADRD +ILTGWLRGNTTGGELIRAGVPDGWVVGDKTGAGGYGTRNDIAVIWPPDRVPIVLAVLSSR +DEKDADYDNALIAEATKVALAGw +>[subseq from] class A beta-lactamase LEN-51 n=1 Tax=Klebsiella sp. P1CD1 TaxID=2267618 RepID=UPI000F4DF0CB +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Eumeta variegata TaxID=151549 RepID=A0A4C1YE18_EUMVA +-qTLTSQLETLESKSGGRLGLAVIDTADGSKY-AWRGNERFPLCSTSKVMAVAAILKKNE +RDPHLLDKKIHISKSDMVNYNPVTRKHIDSYMSVAELSAAALQYSDNAAMNKLLSYLGGP +QQATHFARTIGDKDFRLDRNEPGLNTAIPGDDRDTTTPSAMAESLKKVVLGTALKEEQRA +KLSDWMKGNTTGSDSIKAGLPDDWIVADKTGSGDYGSTNDIAVIWPKNHAPVILTTYFTQ +HDKDAATRKDVLASAAKLVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI00141B6701 +---LRAQWAEIERRTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD +QGELTLAQRVKIRASDMVEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRFAPDDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDSCLRAGLSRGWKIGDKTGNNGTDTRNDIAIVWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0013FDB62B +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTPPSLSARSQQ +QLLQWMVDDRVAGPLIRAELPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAVIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus TaxID=1386 RepID=UPI000B84D1BE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Marinobacter nanhaiticus D15-8W TaxID=626887 RepID=N6VZT2_9ALTE +--AFTHAVADLESAKGGRLGVAVWDTETGDRF-GHRADERFAMTSTFKWVLVAAVLSRVD +AGEETLDRQVRYDDSDILSYAPIAKQHLPEGMTVAELSDAAIRYSDNTAANLLLETLGGP +EGLTDYMRTLGDEVSRLDRYEPELNANLPGDERDTTTPSAMLNAMQAALVGDALSPASKK +RLHDWLIRNTTGDAKLRAGLDPDWTVGDKTGSGARGASNDVAIVWHSDGGPILIAVYYSD +SALSNEAQSAVHAEVGRLVT--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD107 TaxID=1053229 RepID=J8JV93_BACCE +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVDYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas lutea TaxID=243924 RepID=UPI0009DFFE20 +-qTIAQRLVELERRHGGRLGVAILNTASQRLI-DHRGNERFALCSTFKCLAAACVLARVD +QQQEALSRRIVYGREQLVPYSPTTESHAGGQLSVGSLCEAALTLSDNTAANLLLDSIGGP +QALTQWLRSIGDTQTRLDRREPELNENRPGDERDTTTPMALVQTLNTLILGDVLSLPSRD +QLTAWLVNNQTGDKKLRAGLPRGWRVGDKTGSGANNASNDVAILWPGDRAPVLVSVYYTG +SIAGGDQINALMAEIGSLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar navarrensis TaxID=339658 RepID=A0A243AR07_BACTU +-----DSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYNREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGDVLSTKKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIALD-- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000E2C231F +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNGAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLLRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A2W5TF38_AZOBR +---LPAAFAGIERRVGGRLGVAVLDTATGQRA-GYRETERFPLTSTFKLLAAAAVLARAD +AGQARLEQRIRYGREKLVTYSPETEKHAGEEMTLAAICEAAITLSDNTAGNLMLEQLGGP +AGLTAWLRSIGDEVTRLDRWETALNEAKPGDPRDTTSPAAMLASLQRVTLGEALSDKAQA +HLSGWLRASRTGDKRLRAGLPAGWQAGEKTGAGERGTNNDTGLLWPPGGAPILVAAYSTG +STAPGPERDAALAEVATAIVA-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHX8_KLEPN +-----EQIKISESQLAGRVGYIEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMVERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas lutea TaxID=243924 RepID=A0A098T0P8_9PSED +-qTIAQRLVELERRHGGRLGVAILNTASQRLI-DHRGNERFALCSTFKCLAAACVLARVD +QQQEALSRRIVYGREQLVPYSPTTESHAGGQLSVGSLCEAALTLSDNTAANLLLDSIGGP +QALTQWLRSIGDTQTRLDRREPELNENRPGDERDTTTPMALVQTLNTLILGDVLSLPSRD +QLTAWLVNNQTGDKKLRAGLPRGWRVGDKTGSGANNASNDVAILWPGDRAPVLVSVYYTG +SIAGGDQINALMAEIGSLAA--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI000BF5DCD4 +-qATHKEFSQLEKKFDARLGVYAIDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNA +--TEKLNEVVTYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMRDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRN +ILTEWMKGNATGDKLIRAGVPTNWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAAAAKVIVN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. ABP14 TaxID=1892404 RepID=UPI00119F2106 +-qATYKEFSQLEKKYDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVINYTKEDLVDYSPVTEKHVDTGMILGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDNRDTSTAKAIATNLKEFTVGNALPDHKRN +ILTDWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKDAPYDNQLIAEAAEVIVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus gaemokensis TaxID=574375 RepID=UPI00079B2846 +--ATHREFVQLEQKFDARIGVYAIDTGTNRTV-AYRPNERFAYASTYKALAAGAVLQQNS +--IDKLDEVITYTKDDLVTYSPITEKHVDTGMTLGEIAEAAIRYSDNTAGNLLFNKLDGP +NGFEKALKQIGDRVTKADRYETDLNEATPGDIRDTSTAKALATDLKAFTVDDVLSADKRK +ILTDWMRGNTTGDQLIRAGVPKDWEVGDKSGAASYGTRNDIAIVWPPNREPIIIAILSSR +DTQDATYNNELIAQAAKVTIN-- +>[subseq from] Beta-lactamase n=1 Tax=Sorangium cellulosum TaxID=56 RepID=A0A150Q6J4_SORCE +---TAPALARIEAQLGGRLGVAALDTANGARI-GHRAGERFAMCSTFKSLLAACVLARVD +QGQLTLDRRIAYRESDLLEHAPVARARLAEGLTVEELCAAAVEVSDNTAANLLLAQIGGP +AGLTAYLRGLGDQVTRLDRDEPALNTNLPGDPRDTSTPDAMTDTYRSLLVGDALREASRA +RLKAWMVRATTGLARLRAGLPRDWVVGDKTGTGENGIANDVAVAWPPSRAPIVVACFVEA +PSASVDARNAAHAEVARLVAAAf +>[subseq from] Beta-lactamase n=2 Tax=Stigmatella aurantiaca TaxID=41 RepID=A0A1H8D7F7_STIAU +----RSRLAELERRHGGTLGVAVLDTASGELV-LHRADERFPLCSTFKFLAAARVLARVD +RGEEQLGRRIVFSEADLVSYSPVTKEHVGGEMTLEAICEAAITLSDNTAGNLLLDSFGGP +AALTRYVRTLGDKKTRLDRRETELNEAKPGDPRDTTTPAAMLQDMQRLLVGDALSASSRE +RLVAWLTASKTGAKRLRAGVPPDWRAGDKTGTSGNGVVSDIAIFWPPDRAPLLVSAYYRG +PEG---TGDAVLEAVGRLVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. 10 TaxID=1101191 RepID=UPI000488CC78 +-qDLADRFVHIEEASGGRLGIGLLDTGSGAQA-AHRGAERFPLCSTFKILAAGAVLARVD +RGEDSFDRRLRYEPREVVPYSPLSGPRAGGEMTIAELCEAAVTVSDNTAANLLLGTMGGP +AGLTARIRAFGDEASRLDRTEPDLNEAAPGDPRDTTTPLAMAETLRRLVLADALSPASRA +LLTAWLVGCRTGDARLRAGLPKDWRIGDKTGSGENDTANDVAVIWPARRPPLVLTVYLTG +ARTSPEARSATIASVARAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia caffeinilytica TaxID=1761016 RepID=A0A346B6H1_9BURK +--AMRQRLAQIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKLLAAGFVLTRVD +RGQEALERRVVFSKGDLVPYSPATSRHTRERMSVADLCKAAITLSDNTAANLLLASFGGP +AALTAFVRSIGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELLLGERLSSSSRA +QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVTAYLTE +ASGDTARCNAAIAKVGALVA--- +>[subseq from] class A beta-lactamase n=3 Tax=Streptomyces TaxID=1883 RepID=UPI00099F259F +--DVRRRLRELEKSYPGRIGVHALHTGTGATV-GYRADERFAIASTFKVLAAAAILRRAR +EEPGLLDVLIRYGRDDLVEHSPRTELHLETGMTVRELCDATLTYSDNAAANLLMRRIGGP +SGITEFARSIGDAHTRLDRWETDLNTNIPGDRRDTTTPAAMTGNLRGLVLGDALHPLDRD +QLIRWLLENTTGDKRIRAGLPEGWRVGDKTGSPAYGGVNDVAVAWPPKRAPLVISVYTTR +RDPDTPGEDRIAEDITRIVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Phenylobacterium TaxID=2640670 RepID=UPI00083AA7D7 +--SADAALADLERRHGGRLGVVIWRPADGLRI-ARRADERFAMCSTFKTLAAAAVLARVD +RGREDLARRIVFGKDQVVTYSPVTGPRVGGEMTLSEICAAAIRYSDNTAGNLLLDSLGGP +AGLTRFARGLGDGITRLDRYETLLNEATPGDPRDTTSPEAMARNLRKLLLGPALSPESRR +RLSQWMASNTTGDARIRRGIPMGWVVMDKTGAGENGANNDVAVVLPPSGQPAIVTVYYAE +SQATGAQRNAVIADVARVAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD5410A +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAAGFVLARVD +QGTEKLDRRVTYGKDKIVTYSPETEKHADGDMTVAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRE +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE +ATAPAKDVEAVFAEIGKIVV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus aryabhattai B8W22 TaxID=1358420 RepID=A0A1G7DEL2_9BACI +----KHHFVKLEDKFDARLGVFALDTGTNQTV-TYRADERFIYASTSKALAVGTLLQQKT +--IEDLNQRITYTQDDLVNYNPITEEHVDTGMTLKELCDATLRYSDNTAMNLILKQIGGP +NGLEKALRDVGDNVTMPERFEPELNEVKPGETHDTSTPRALATSLQSFTLGDALPVEKRG +LLIDWMKRNTTGDSLIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPPKGDPIMLAILSSR +DKKDANYNDKLIAEATKEVINAy +>[subseq from] Beta-lactamase n=1 Tax=Bacillus tropicus TaxID=2026188 RepID=A0A4Y6FAD3_9BACI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTA-NLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Ensifer adhaerens TaxID=106592 RepID=A0A0L8BQ93_ENSAD +--SVDARLAELEKRTGGRLGVSVLDMETNISF-GCREDERFAMCSSFKTLAAGFILARAD +QGAEKLDRRIVVAQKDIIAHSPVTEKHIGGKMTIAELCAATMTTSDNAAANLLLERFGGP +PALTAWLRTIGDETTRLDRNEPGLNEAQKGDPRDTTTPAAMLETLGKLAFGPALTETSRK +LLVEWMVANTTGDLRIRAGLPKGWRVGDKTGTNGNGAASDIAIVWPEGRGPLLLAVYIAE +ATAPLAELNAVFADVGRMAAE-- +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium 13_1_20CM_3_54_17 TaxID=1805405 RepID=A0A1Q7UYU7_9BACT +--DAATRIAAVEARIGGRIGVAALDTGNTKHV-EHRADERFPMCSTFKFLAAAAVMKRVD +EKKEKLERFVPYGAKEILEYAPVTKEHLKDGMTLGALCAAAIEQSDNTAGNLLLDAIGGP +SGLTNFVRSLGDRVTRLDRIEPELNSAIPGDERDTTTPAAICSDIQRLLLGDALSEASRR +QLEDWLQRNETVGPMIRAGVPKNWILGDKTGRGSNGATNDIAIMRPPGRAPILLAIYSVG +STATPNDRAAAVAEVTKIVVESf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar navarrensis TaxID=339658 RepID=A0A243A300_BACTU +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0009918E22 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. H3(2019) TaxID=2598724 RepID=A0A558F0F2_9PSED +--ELYKKLAELENSAKGRLGVALINTANGHEI-QYRGGERFPFCSTFKLMLAAAVLHKSM +AEPGLLEKHIAYAEADLLSYAPIAKQNLKQGMSVAQLCAATLQYSDNTAANLLIKELGGV +AAVNLFAKGLGDPAFRLDRREPELNTAIPDDPRDTTTPAAMAASVQKVVLGDALATAQRE +QLATWLKGNTTGDASIRAGTPAGWIVGDKTGSGDYGTTNDVAVLWPQTGAPVVLAVYFTQ +YQKDAEARRDVLATATRLVMAH- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFEA18A +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--ANKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRTSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI0004D6AF5B +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTALLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] class A broad-spectrum beta-lactamase OKP-B-45 n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000651787B +-----EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAGIGAALIEHw +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-35 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2U9IB43_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELEPNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia rohdei TaxID=29485 RepID=UPI0011A77F71 +--SLDKQLAELEQQSQGLLGITVINTGNGRKI-QYRGTQRFPFCSTFKFILAAAVLNKSA +SQPKLLDKHLHYHERDLLSYAPITRKNLAHGMSVSQLCAATVQYSDNTAANLLIQELGGV +ESVNQFARSIGDQTFRLDRLEPELNSALPNDPRDTTTPSAMAASMNALVLGDALPAAQRE +QLAVWLKGNTTGGETIRAGAPAEWVVGDKTGTGDYGTTNDIAVLWPTKAAPIVLVIYFTQ +REKDAKPRRDVLAAATKILLSH- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RQ59_9BACT +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLAGVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00144230F5 +--NIEHRLADLEKRTGGRLGVSVLDTETSISF-GYRGSETFPMCSTFKALAAAFVLARAD +KGEENIYRRVSYGKDKLVDYSPISEKHAGADMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPNAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A679GZL5_9BACI +-----DSFVKLEKEFDAKLGIYVLDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD021 TaxID=1053224 RepID=R8HNN6_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +VLTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAAYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T942_9BACT +-----------EDQLGARVGYIELDLDSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLRNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000C7A2B48 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHISGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. GW458P TaxID=1981504 RepID=UPI000A31ED6A +--AAQTQLAALEQVAGGRLGVAAWRQGSEQRV-AYRADERFPLCSTFKAMLAGAVLARSA +SQPGLLEQQVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTILGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDSWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPGGAPLLIAVYYTR +EQKNADTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. L43 TaxID=2035452 RepID=A0A2A6HXG7_9RHIZ +-dNIQRRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARAD +KGEEKLDRRVSYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +VALTDWLRSIGDGTTRLDRTEPTLNEGKKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +RLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVKDLNPVFAEVGRMIIE-- +>[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus sp. LC231 TaxID=1120679 RepID=A0A1S2F1S2_9BACL +----------------IELYVGVQDLSGGGKI-QAGSSNVYYAASTIKMAIVTALMQDIE +AGKYALEQTVQVKPEQVVGGAGSLKDKFPQEITIERLAGLMITQSDNTATNALIDLL-GF +ERINTLIDEQGFETMQLGRKMMTPAKS--PAADNYVNGEELLTLLERIYAGEIVSAQSRD +QILAWMKAQEV-KTKFGAALP-GKPIAHKTGELGD-VSHDIGYFLVPGRE-VAVTVLTKV +TKKAQELGNPVVQRAAKAVYN-- +>[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus sp. LC231 TaxID=1120679 RepID=A0A1S2F1S2_9BACL +-----------AEEKGIRVSVGLKDLSDDREL-LLGSRQSYMPASTIKMALVSALMKEVD +AGRLTLEQKVKVEQEDVVGGTGSLQKETPQDVTIERLARLMITQSDNTATNVLIDVV-GL +NKVQALMDELGLDVMHLGRKMFAAA--PTPEQDNYINAEDLVHLLANIHSGEFLSDNSRD +QIIDWMKAQEV-DTKFGAALP-DAPIAHKTGENAN-VTHDAGYFLLPGRE-IAISVLTEV +TTEAQAIGNPVVQEIAKAVYE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000992529E +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-TYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIADAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000B1CC87E +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVPAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. ARR65 TaxID=1040989 RepID=UPI0004631E50 +---LPDAFAEAEADSGGRLGVAVLDSAAGAAI-GHRENEHFPMCSTFKVLAVAAVLSRID +AGKEQITRRIRIAPGDLLAYAPVTQQHVGADMSVADLCEAALTLSDNTAANLLLASLGGP +SAVTQYARALGDDLTRLDRVEPDLNTADAGDLRDTTTPLAMARNLTALATGTALSPASRE +LLINWLIGCKTGDAKLRAGLPKTWRVGDKTGSGAHGTSNDVAVIWPPGRAPLIVTMYLTE +TALPDDKRNATFAAIGREI---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A4R1EFZ5_BACCE +---TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQKNS +--IEKLNEVVTYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRLETELNEAIPGDNRDTSTAKAIATNLKDFTVGNALPDQKRN +ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=A0A5R8P8B6_9NOCA +-----PRFAALETTTAARLGVFAVDTGSERTV-AHRADERFPMASTFKGLACGALLREHP +LSTGYFDQVIHFSAEELVEYSPVTETRVESGMTVAELCDAAITVSDNTAGNQLLKLLGGP +QGFTAFLRSLGDDTSRLDRWETELNTAIPGDERDTTTPAALAADYRALVVGDVLGEPERA +QLTAWLVANTTGDTRIRAGLPEDWTVGDKTGSPAYGSALDVAVTWPPGRAPIVIAVLSTK +SEQDAEPDNRLVADATRTVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEE8935 +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVKIHASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQLASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase n=2 Tax=Acidovorax konjaci TaxID=32040 RepID=A0A1I1SZQ7_9BURK +---LQEALQRIEASVGGRLGVGLLDVEAGRQA-AYRGDELFPLCSTFKLLLAAQVLRRVD +QGQERLDRRITYRKVDLVDYSPATAPHADGEMTVAQLCEAAVTLSDNTAANLLLDSQGGP +QGLTAWLRSLGDAHTRLDRKEPELNDVPEGEVRDTTTPRAMARTIWAITHGEALSAAGRR +QITDWLVGNRTGDKRLRAGMPQGWRIGEKTGTGPRGTSNDAGLFWPPGRKPVMVSSYLTG +SPAEPARRDEAIAQVGALAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000F8DF1C0 +---LRAQWAEIEHRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLTAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1J9V3Q1_BACCE +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEMAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. 602-1 TaxID=2492472 RepID=A0A3R8MA35_9CAUL +--ALSSRINELERRSGGRLGVAVLDTQDGRRF-AWRGDERFRMCSTFKMPLAAAILRRVD +QGRERLDRRVTYGREVLMGNSPAVEKHLAQGMTIGELCAATITLSDNAAANLLLDALGAP +TDLTRFLRALGDQTTRCDRREPELNTGAPDDPRDTTTPAAIVETWKTLLTTDALSTASRK +RLTAWVVANRTGDKRLRAGLPRGWKVGDKTGNNGQDQTNDIAVIWPPGRKPLFVSAFHDQ +GSADDDVRSAVLADVARAVV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mobilis TaxID=2026190 RepID=A0A386V1Q2_9BACI +---TYKDFSQLEKKFDARLGVYAIDTGTNQKI-SYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYKKEDLVDYSPVTEKHVDTGMTIGQIAEAAVRYSDNTAGNILFHQIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=Q4L1Z9_RAOOR +heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYCAGERFPMMSTFKVLLCGAVLSRVD +TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP +QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ +QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA +TPASMDERNKQIAAIGETLVRHw +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Chromobacterium sp. MWU14-2602 TaxID=2073169 RepID=A0A2S5DA09_9NEIS +------KFAKLEKDFGGSIGVYAIDAGSGATL-SYRADERFPLCSSFKGFLAAAVLAQEQ +KQAGLLDKRVSYGKEALISWSPITEKHQAKGMTVAGLSAATVQYSDNAAANILLKELGGP +AQLTAFMRSIGDQTFRLDRREPELNTAIPGDARDTSSPRAVAESLRKLTLGSALAAPQRQ +QLIDWLKGNTTGDKRIRAAVPAGWAVGDKTGTCGYGTANDYAVIWPTGRAPVVLAVYTKA +QDKALKSSDAAIAAAAKAALE-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia caribensis MBA4 TaxID=1323664 RepID=A0A0P0RAH1_9BURK +--ALERQLAEIEARTGGRLGVAILDTAGAKQQ-GWRMHERFPMCSTFKFLLASAVLVRKD +QGKEQLGRKIVYAKEVVVANSPVSGPRAGGDMAVGELCEAAITRSDNTAANLLLDSIGGP +AALTAFARSIGDRITRLDRNEPTLNEATQADPRDTTTPAAMLADLRTLLLGEHLSAASRE +QLTAWLAANKTGDTRLRAGLPKAWRVGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG +ATASATQRDAAIAQVGTLVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C3D872_BACCE +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRLETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK +VLTEWMKGNATGDKLIRAGVPTDWEVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] Beta-lactamase n=1 Tax=Aureimonas ureilytica TaxID=401562 RepID=A0A175RTX0_9RHIZ +--DLDALWAEIESRFSARLGAFVWDMETDRRW-ARRADERFPLCSTFKLVAAAGLLARVD +AGQENLSRRVVIAKSDLVTYSPETEKHVGGEMTLSSIAEAALTQSDNTAGNVLIDLLGGP +EGVTRTARGFGDESFRLDRRETALNEAKPGDPRDTTSPAAMTKTLHALLFGKALKPDSRR +QLADWMVANRTGDAKLRAGLPKDWRVGDKTGGGDFGTMNDVAVIWPPAGKPILISLYLTE +TKASFDERNAAFAEIGRAL---- +>[subseq from] Mutant KPC family beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A6B7HYA8_ENTCL +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARHTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B5NIJ0_9BACI +-nKVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKNVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLRELGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN +LLIDWMKRNTTGDSLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPTVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI001034D81C +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSACSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia insulsa TaxID=1441714 RepID=A0A2T1ASV5_9BURK +-eAIRQRLAQIEAESGGRLGVSILDTTSGLHT-GLRTDERFPMCSTFKLLTAGFVLMRVD +HGQETLERRVVFSKGDLERYSPATSRHTRELMSVADLCKAAITLSDNTAANLLLASFGGP +AALTAFARSIGDGVTRLDRNEPTLNEATPGDPRDTTTPNAMLGDLRELLLGERLSAPSRA +QLLAWLAANQTGGERIRAKLPKDWGVGDKTGSGDHGTANDVAILWPPGRGPILVTVYLTE +TSGDAARCNAAIADVGEVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A4Q9YNH7_BACMY +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTRQDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIALD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI00099264CE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKKATYDNKLIADAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. WMMC415 TaxID=2675222 RepID=UPI0012B4835F +----DREFRRLEERFDARLGVYAIDTGTGRTV-GYRADERFAYASTFKALAAAEVLDETT +--DAELDRVVRYSADDLVTYSPITERHVADGMTLRAIADAAVRYSDNTAGNLLLRRLGGP +QKFEKELREVGDKVTDPARYETALNEARPGDRRDTSTARAMAQDLRAYAVGDALEPADRD +ILNGWLRGNTTGGELIRAGVPDGWVVGDKTGAGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DQKDAGYDNALIARAAEVVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudovibrio sp. (strain FO-BEG1) TaxID=911045 RepID=G8PND4_PSEUV +--ELLDTVNRLENEVGGRIGVVLQHTGSDWAI-ETRADERFPMASTFKALLCGAVLARVD +RGEERLGEVVAFSKAELVSYSPVTKKHVAEGMRVGELCEATVTMSDNTAANLLLKRVDGP +KGLTRFLRGLGDRVTRLDRREPEMNEAKPGDARDTTSPRAVVQTLDRLLFEEVLQPSSRA +QLQQWMVDDKVADALIRKHLPSDWRIADKSGAGHNGSRGIIAAIWPKTGKPYLTAVYMTG +SDADFKKRNAVIAEIGKAIVE-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00133002E8 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKYLADGMTVGELCAAAITMSDNSAANLLLATVGGP +VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTPPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDD2755 +-dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +KGDESLDRRITYGKDKLVTYSPETEKHAGGDMTMAEICKAAITLSDNTAGNLMLESFGGP +AALTDWLRSIGDGTTRLDRMETALNEATKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN +QLIDWMIANTTGGARLRAGLPGDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYIGE +ATVKMDEFNPVFAEIGKMITE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sullae TaxID=50338 RepID=A0A2N0D2D8_RHISU +-dDIERRLAGLEKRTGGRLGVSVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD +KGEENLERRVIYHESKLVSYSPETEKHVGGEMSVAELCKAAITLSDNTAGNLLLESFGGP +EALTKWLRSIGDRSTRLDRWETALNEGKKDDPRDTTTPDAMLDTLGNVALGSVLSEPSRN +TLIGWMMANTTGGARLRAGLPGSWKVGDKTGTGNNGTAADIAITWPKGRGPILVTTYIAE +ATAPVKELNPVFAEVAKIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Cobetia sp. L2A1 TaxID=2686360 RepID=UPI00131E1D0B +----QDSVRTIEQEVDARMGVAVLDTADGTRF-TYRGDERFPMSSTFKALACGSMLALVD +AEQESLQRKVKIKPEAVVTYSPVTETQTEGDLTLSELCNAAVTISDNTAGNLILDAVGGP +AGLTAYLRSLGDDTTRLDRTETSLNEATPGDVRDTTTPNAMVTTLQKLLLGDALSEDSRI +KLQSWLLANTTGEGKLRDALPAGWQIGDKTGGGGHGTNNDVAIIWPPGHAPLIVAVYLTE +SDASLAQRNAAIAGIGRLLVT-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. YR213 TaxID=1881027 RepID=A0A1G8FDT2_9BURK +--AAQTQLAALEKAAGGRLGVAAWRQGSDLRV-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLDQHVRYEKKDLVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuB1-1 TaxID=1053207 RepID=J9C608_BACCE +----NDSFANLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELAAASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF35914 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALVVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pragia sp. CF-509 TaxID=2589859 RepID=UPI00112C3AAC +---IQQNLADLEKSTGGRLGVVLINTADNSQI-IYRGDERFPMCSTSKMMVVAGVLKQSE +SQKGLLDQQVDIKKKDLVSHSPIAEKRLNNKMSLAELSAATLKYSDNAAMNKLIEQLGGP +QKATAFARSIGDQSFRLDRTEPTLNTAIPGDKRDTTTPLAMAVSLQKLTLGEALAAPQRA +QLVEWLKGNTTGAASIRAGLPAEWVVGDKTGSGSYGTTNDIAVIWPKDKAPLILVTYFTQ +NEKNAKSRREVLASAAKIV---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKH7_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYPPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHATRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. URHA0054 TaxID=1298859 RepID=UPI0004257CE4 +--AIRARLEEIEAQSGGRLGVSIVDTTSGLHA-GLHADERFPMCSTFKLLAAGAILARVD +RGEEDLQRRIVYPESELVPYSPATSKHTRERMSIAELCKAAITLSDNTAANLLLQSFGSP +AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNMRELLLGERLKSSSRV +QLLAWLAGNETGGARLRAKLPKDWGVGDKTGTGDHGTANDVAIFWPPGRGPVLVAVYLTG +TAGDAARNNAAIANVGALVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus velezensis UCMB5033 TaxID=1338518 RepID=S6FQZ7_9BACI +---LNQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAETAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. San01 TaxID=2494256 RepID=A0A3S2YZ26_9ACTN +--DARRRLRELEAGYPGRIGVHALDTGTGACL-AYRADERFAIASTFKVLAAAAVLRRAR +EEPGLLDVLVRYTRDDLVAASPRTTMHLETGMTVRELCDATITYSDNTAGNLLLRRIGGP +SGVTAFARSLGDRETRLDRWETDLNTNLPGDPRDTTTPAAMTADLRALVLGDALHPLDRG +QLTRWLVENTTGDKRIRAGLPPGWRVGDKTGSPAYGGVNDVAVAWPPGGAPLVISVYTTR +LDADTPGEDRIAADITRIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1Y6AQI4_BACCE +hqATHKEFSKLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQYS +--TEKLNDVITYTKDDLVEYSPVTEKYVDTGMKLGEIAEAAVRYSDNTAGNILFHQIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNVLPVHKRN +ILIEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Janthinobacterium TaxID=2610881 RepID=A0A2G3KKX9_9BURK +--AAQTQLAALEQVAGGRLGVAAWRQGSEQRV-AYRADERFPLCSTFKAMLAGAVLARSA +SQPGLLEQQVRYEKKELVTYSPITEKHLADGMRVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDSWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPGGAPLLIAVYYTR +EQKNADTNQDIITAATRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter sp. SA187 TaxID=1914861 RepID=UPI0009345718 +---TLSAVKQAETTLAARVGYAELDLASGKVLnSYRQDERFPMMSTFKVLLCGAVLARVD +AGQEQLNRRLTWQKADLITYSPVTEKHLADGMTVAELCDAAITLSDNTAANLLLSTLGGP +QKLTDFIRKTGDGTTRLDRVEPELNEALPGDVRDTTTPTAMAKTLRQLLTGDTLTAASRQ +QLARWMEEDKVAGPLLRSVLPAGWYIADKTGAGERGSRGIVAALGPDGTPSRIVVIYVTG +SKATMDERNKAIAAIGEAVIKQw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF65F29 +-----DSIVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000F5B8FC3 +---LNQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAETAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium ecuadorense TaxID=1671795 RepID=UPI0006734470 +-dDIEKRLAALEKRTGGRLGVSVLDTQTSISF-NYRGSEAFPMCSTFKALAAGFALARAD +KGQESLDRRVTYGRDKLVDYSPLSEKHAGADMTITELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTTPDAMLDTLGNLTLGSILTEASSD +RLIAWLVASTTGGERLRAGLPKEWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus proteolyticus TaxID=2026192 RepID=UPI000A03F9C8 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVINYTKDDLVEYSPVTEKHVDTGMTLGEIVEAAVRSSDNTAGNILLNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATTLKAFTVGKALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNKAPIIIAILSSK +DEKEDTYDNQLIAEAAKVVIN-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2B2JY17_BACCE +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVVAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Pseudomonas TaxID=286 RepID=A0A0N9WJ97_PSEFL +--ELYKKLAELENSAKGRLGVALINTANGHEI-QYRGGERFPFCSTFKLMLAAAVLHKSM +AEPGLLEKHIAYAEADLLSYAPIAKQNLEQGMSIAQLCAATLQYSDNTAANLLIKELGGV +AAVNLFAKGLGDPAFRLDRQEPELNTAIPEDQRDTTTPAAMAASVQKVVLGDALATPQRE +QLVTWLKGNTTGDASIRAGTPTGWIVGDKTGSGDYGTTNDVAVLWPQTGAPVVLAVYFTQ +HQKDAEARRDVLASATRLVMAH- +>[subseq from] Beta-lactamase n=1 Tax=Izhakiella australiensis TaxID=1926881 RepID=A0A1S8YML9_9ENTR +-sDLHQQLEALEKQHNGRLGMTLIDTASGHSL-QYRGNERFPMCSTSKALLAAAVLNLSL +RQPDLLERRIHWDKSEKLSWMPVTEKHQDSGMTVSELCQAMIQYSDNLAANLMLKLVGGP +AAVTAQARALGDQVTRLDRTEPTLNSAIPGDERDTTTPLAMARDLQKLAFGSGLPPRERQ +LWIGWLRGNTTGKQSIAAGVPSGWQVGDKTGSGDYGTTNDAALLWPPQRQPLVLTVYFTQ +PEKAAPSNRAVLAESARLTLAAw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00084CD7A2 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. EKM20T TaxID=2708059 RepID=UPI00142E615A +--TLKSQFETLENKSVGRLGVTVVDTSDGSEY-SWRGNERFPLCSTSKVMAVAAILKKNE +SDHSLLDKKIHINKSDMVNYNPITQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP +QQATHFARTIGDKAFRLDRKEPELNTAIPDDVRDTTTPSAMADTLNKLVLGTALKGEQRA +KLSEWMKGNTTGANSIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKDQAPIILTTYFTQ +KDKDAVARKDVLASAAKLVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus qingshengii TaxID=334542 RepID=A0A4R5ZRM4_9NOCA +--HIHREFAELESKFDARLGVYAIDTGTNRTV-SYRPNERFAYASTYKALAAGALLQHYS +--IDQLDELVTYTSEDIVSYSPVTELHVDTGMTLREVIEAAVRYSDNTAGNLLLKKLGGP +EGFETTLRQIGDNVTQVDRYEPDLNSAVPGDKRDTSTPKSLATSLQAFAVSDFLSTEKRK +ILTDWMRGNTTGDALIRAGAPTGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAILSSR +YTENATYDNALVAEAAKVAL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia guartelaensis TaxID=2546446 RepID=A0A4V2ZWI5_9BURK +--AVEKQLAAIEAQAGGRLGVAMLDTANGHVR-GWRMHERFPMCSTFKVLLASAVLTRKD +HGKEDLARKIVYSTAQVVSYSPVSGPRAGSGMTVAELCEAALTRSDNTAANLLLESIGGP +PAITAFARSIGDPVTRLDRNETTLNEAIPGDPRDTTMPAAMVANLRELLLGERLSAASRE +QLIAWLVANKTGDARLRAGLPKDWRVGDKTGTGDHGTANDVAIVWPTGRAPILVTTYLTG +AMASSAQRDAAIARVGV------ +>[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00062CAFE3 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMXTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWNPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKXAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Nocardia terpenica TaxID=455432 RepID=A0A291RJM4_9NOCA +---ATTEFASLETEYGARLGVYAVDTGSGRTV-AHRADERFAYASTLKSLAAGAVLQSVP +--PAGLDERITYTRADLVPNSPVAEQHVDGGMTLRETLDAAVRYSDNTAANLLVAKLGGP +KGLQRRLRDLGDTVTQVDRTEPDLNEATPGDPRDTSTPTAFAADLRRYVLGPVLTDPARA +LLTEMLRANTTGGELIRAGVPAGWVVGDKTGLGSYGSRNDVAVLWPPHAAPIVLVVFTTR +PDKDASYDNALIAKAAAAAVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A1S9X099_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB1D15 +-dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +KGDESLDRRITYGKDKLVAYSPETEKHAGGDMTMAEICKAAITLSDNTAGNLMLESFGGP +AALTDWLRSIGDGTTRLDRMETALNEATKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN +QLIDWMIANTTGGARLRAGLPGDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYIGE +ATVKMDEFNPVFAEIGKMITE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. SRB_28 TaxID=1969378 RepID=UPI000DC4594F +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAAYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WG11_9BACT +---LSDAMAALERRSGGRLGVAVLDTGSGRRF-DWRGNEMFPMCSTFKFLLAAAILKRVD +EGRESLTRRIPVSPGDLIPYAPFAETRVNGTPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFVRSLGDERTRLDRNEPTLNSSIPGDPRDTTTPNAMVHSMDRLMVGDALRPSSRE +QLIGWMVGNKTGDKRLRAGLPRDWRVGDKTGTGN-GSFNDIAIVWPGASPPILIASYVTQ +TPEGFKQGDAIHAEVARAAAGAf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1S9TE91_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIADAAEVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacillus licheniformis TaxID=1402 RepID=P94458_BACLI +-tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-TYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALATSLQAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPEGWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVVK-- +>[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. (strain FO-BEG1) TaxID=911045 RepID=UPI0002FA5D02 +--ELLDTVNRLENEVGGRIGVVLQHTGSDWAI-ETRADERFPMASTFKALLCGAVLARVD +RGEERLGEVVAFSKAELVSYSPVTKKHVAEGMRVGELCEATVTMSDNTAANLLLKRVDGP +KGLTRFLRGLGDRVTRLDRREPEMNEAKPGDARDTTSPRAVVQTLDRLLFEEVLQPSSRA +QLQQWMVDDKVADALIRKHLPSDWRIADKSGAGHNGSRGIIAAIWPKTGKPYLTAVYMTG +SDADFKKRNAVIAEIGKAIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus pacificus TaxID=2026187 RepID=A0A3P1BPS1_9BACI +hqATHKEFSKLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQYS +--TEKLNDVITYTKDDLVEYSPVTEKYVDTGMKLGEIAEAAVRYSDNTAGNILFHQIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNVLPVHKRN +ILIEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=2 Tax=Skermanella aerolata TaxID=393310 RepID=A0A512DMQ9_9PROT +---LSDVMAALERRSGGRLGVAMLDTGSGRRF-DWRGDEMFPMCSTFKFLLAAAILKRVD +EGRESLTRRIPVSPGDLIPYAPFAETRVNGTPTVAELCEATMTLSDNVAANLLLPAVGDP +AGLTAFVRSLGDERTRLDRNEPTLNSSIPGDPRDTTTPNAMVHSMNRLMVGDALRPSSRE +QLIDWMVGNKTGDKRLRAGLPRDWRVGDKTGTGN-GSINDIGIAWPGARPPILIASYITQ +TPEGFKQGDAIHADVARAATGAf +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0009BAABA8 +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP +AGLTAFLRQFGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000B517F44 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNP +--IEKLNDVIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR +FTKDANYDNALIAEAAKVALD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis subsp. medellin TaxID=79672 RepID=A0A243NKQ9_BACTV +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=A0A369CNM5_BACAM +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. RUPDJ TaxID=1907305 RepID=A0A1N7D655_9BACI +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEC367F +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=B5ULZ6_BACCE +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=A0A4U9BNP2_KLEPN +-----EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI0006A88175 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A5B9HV90_BACCE +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0012F96446 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium svalbardensis TaxID=368607 RepID=A0A290WSX4_9BURK +--AAQTQLAALEQAAGGRLGVAAWRQGSELRV-TYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLVIAVYYTR +EQKNADTNQAIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 112mf TaxID=1761752 RepID=A0A1H4CV12_9BACI +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF3F694 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD014 TaxID=1053223 RepID=J8GPN4_BACCE +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLRAIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. BJB304 TaxID=1572871 RepID=A0A2G3M8D2_9BURK +--AAHTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMRVAELCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNNAIPGEVRDTTSPASMAHSLQQLLLGNSLPAPQRQ +QLATWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLLIAVYYTR +EQKNADTNQDIITAATRIVT--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00065D48DD +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI0007ED6069 +---LRAQWAEIERRTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLVQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLADWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDASLKAVAAAVRD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. BK463 TaxID=2587008 RepID=UPI000DE10D41 +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAAGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHAGGDMTIGELCAAAITLSDNTAGNLLLESFGGP +AVLTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE +ATASAKDVEAVFAEIAKIVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000DF1429C +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI000DE8A1F8 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0011A6C8E1 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD79981 +-dDVDQQLAALEKRTGGRLGVSVMDTGTNVSF-TNRETERFPLLSTFKVLAAGMVLARVD +GGDENLERRVTYDQDKLVTYSPETEKHVGAEMTVGELCKAAITLSDNTAGNLLLDSLGGP +EALTKWLRSIGDTSSRLDRIETELNEARKDDPRDTTTPDAMLDTLGNLALGTVLSEPSRQ +QLIDWMIANTTGAARLRAGLPEEWKVGDKTGTGSNGSAADIAIIWPEESSPILVAVYVAE +ATAPVSELNDVFAEVAKLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000F8E88EF +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. RUPDJ TaxID=1907305 RepID=UPI001115678F +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A437SHI4_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMRDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0011DF58C2 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000BA751ED +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI0010ABE063 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=A0A376I5A8_ECOLX +-pTTLNKVKEAESQLTARVGYAELDLISGEILeSYRLQERFPMMSTFKVLLCGAVLARVD +AGKERLDRRIPFSRRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGP +QGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILRTTSQQ +QLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYVTE +SQATLEERNRQIAGIGATLIQHw +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. 11515TR TaxID=2028343 RepID=A0A248W450_9RHIZ +--DVDKQLADLEKRTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD +QGTEKLDRRVSYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGDNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE +ATASAKDVEAVFAEISKIVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001444187F +----NNSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--TEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVNPGETHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0012B9D365 +-----EQIKISESQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1E8B8G5_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLKEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTAGNALPTDKRK +ILTEWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora coxensis TaxID=356852 RepID=A0A1C5J3Q0_9ACTN +----EHEFRQLEEKFDARLGVYAIDTGSGRTV-GYRADERFAYASTFKALAAAEVLDETT +--DAELDRVVRYSADDLVTYSPVTERHVATGMTLRAIADAAVRYSDNTAGNLMLRQLGGP +QKFEKELREVGDKVTDPARYETALNEARPGDRRDTSTARALAGTLRAYAVGDALEPADRD +ILNGWLRGNTTGGELIRAGVPDGWVVGDKTGAGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEKDASYDNALIAEATKAVLASw +>[subseq from] GIL family class A beta-lactamase n=1 Tax=Citrobacter sp. wls718 TaxID=2576418 RepID=UPI0010C96F0E +-pTTLNKVKEAESQLTARVGYAELDLISGEILeSYRLQERFPMMSTFKVLLCGAVLARVD +AGKERLDRRIPFSRRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGP +QGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILRTTSQQ +QLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYVTE +SQATLEERNRQIAGIGATLIQHw +>[subseq from] Beta-lactamase n=1 Tax=Methylorubrum salsuginis TaxID=414703 RepID=A0A1I4MGC4_9RHIZ +----EDTLAQIEGRVGGRLGVALLDTASGELT-GRRIDERFPLCSTFKVLAAAAVLARVD +GGQESLERRIVFGREALVPYSPVTEPRIDGSMSLAELCEVAVTRSDNTAGNLLLQALGGP +PGLTAHLRSLGDRVTRLDRTEPTLNEAAPDDPRDTTSPAAMVRVLAGLTLGSALSQPSRD +RLNGWLRDNRTGGARLRAGLPPGWRIGEKTGTGERGTTNDVGVLWPPDGAAQVVAVYLTG +SDRPLAEREAALAAVAKAVVE-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Pseudomonas viridiflava TaxID=33069 RepID=UPI000F05B74B +--ETLVKVKDAEDQLGARVGYIGLDLNSGKILeSFLPEERFPMMSTFKVLLCGAVLSRID +AGQEQHGRRIHYSQNDLVEYSPVTEKHLTGGLTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI00124AAC2B +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI00123716A4 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=J8IM46_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0010A3977D +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A150BSY9_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Legionella taurinensis TaxID=70611 RepID=A0A4T0YGN7_9GAMM +--SLQQKLAALEASAGGRLGIAAINQANGMTI-QYHARQAFPLCSTSKAMSVAALLSQNM +RNKTLLQEKIHYSKQDLVVHSPETEKHLADGMTLAELCEATITQSDNAALNLILKKIGGP +GAVTAFARSIGDKQFRLDRFEPDLNTGIPGDPRDTTTPKAMALSLQKLTTD-TLAAPERQ +LLITWLRNNTTGGARIRAGLPEGWVVGDKTGTGDYGTSNDIGVIWPPHCQPVTLAVYFTQ +PKVDATPNNDVIAAATRIVISAf +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus sp. BC25 TaxID=1144308 RepID=J2PY73_9BACL +---MDLKFAALEKKFDARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP +--LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP +KGFESALRQIGDSVTTSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGDALSAEKQT +ILIEWLQGNTTGDKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPSNKKPIVIAVLSSR +DKQDATYDDALIAEATKVAVD-- +>[subseq from] Beta-lactamase n=2 Tax=Acidovorax valerianellae TaxID=187868 RepID=A0A1G6IGI5_9BURK +-----QQLESSLEGRGARLGVAMLDTGSGLSL-GWRQDERFPMASTFKLLLAAWMLERVD +RGQEALDRRVHFEPSALVAYSPVTEKHVGAVITVGELCDATVTLSDNTAANLLLARHGGP +QGYTAFVRGLGDAVTRLDRTEPTLNEATPGDPRDTTTPLAMLQSLRKVALGDALQPASRA +QLVEWIVGTKTGDKRLRAGVP-GWRVGDKTGTGNQGSSNDIGVLWPPGGAPIVVTCYMTQ +TTTAPEKRDATIAEVARQVAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. ERR1071 TaxID=2572677 RepID=UPI00119C4300 +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGTYADIAVIWPPERGPVLVTTFVAE +ATAAAKDVEAVFAEVSKIIVD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A7F9J3_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium etli bv. mimosae str. Mim1 TaxID=1328306 RepID=S5RUX8_RHIET +--NVEHRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGEENLERRVTYGRDKLVDHSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTEWLRAIGDGTTRLDRTEPTLNEGRKDDPRDTTSPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATASVKDLNSIFAEVGKMITE-- +>[subseq from] carbapenem-hydrolyzing class A beta-lactamase KPC-55 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001435C375 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVNTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1W6AGX8_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TGKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAAYDNQLIAEATEVIVK-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-28 n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1L3HS68_ECOLX +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGV-YANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Class A beta-lactamase n=5 Tax=Streptomyces TaxID=1883 RepID=A0A5P2BMS0_STRVZ +--DAAHRLRALEESYPGRIGVHALHTGTGAVV-AYRADERFAIASTFKVLAAAAILRRAR +EEPGLLDVLIRYGRDDLVTYSPRTEMHLETGMTVRELCDATITYSDNSAANLLMRRIGGP +AGVTEFARSLGDSRTRLDRWETDLNTNIPGDRRDTTTPAAMTANLRELVLGKALHPLDRG +QLIRWLVENTTGDKRIRAGLPEGWRVGDKTGSPAYGGVNDVAVAWPPKQAPLVVSVYTTR +LDPDTPGEDRIAEDITRIAVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI001363C342 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPEGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] BBI family class A beta-lactamase n=1 Tax=Brevibacillus sp. Leaf182 TaxID=1736290 RepID=UPI000701581A +---MDLKFDALEKKFNVRLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP +--LEELDKVITYTKDDLVTYSPVTEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP +KGFESALRQIGDSVTTSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGDVLSSDKQT +ILIKWLQGNTTGDKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR +DKQDATYDDALIAEATKVAVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00069E0E9A +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAVMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1DC51_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLKEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTAGNALPTDKRK +ILTEWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Uncharacterized protein n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A1W0DBX4_9NEIS +----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPMCSSFKGFLAAGVLAQSQ +AKPGLLDKRIRYSKTALPNWSPITTKNQANGMTVAELSAATVQYSDNGAANLLLKEINGP +AALTAFMRTIGDASFRLDRLEPELNSAVPGDPRDTSTPKAVAESMQKLALGKALPEPQRQ +QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDYAVIWPPKRAPIVLAVYTKH +AKKEAKHSDEVIAAAARAALEAf +>[subseq from] Beta-lactamase n=1 Tax=Massilia plicata TaxID=321984 RepID=A0A4P7B939_9BURK +------TFYSIERNLGGRLGVATIDTATGEND-GHRRDERFPMCSTFKTIVAAAVLARSV +TERGFLRKRLRYTQADIRPHSPVSEKHVADGMTTADLCAATIQYSDNAAANILMQELGGP +AAITAYARTLGDTTFRLDRWETELNTAIPGDERDTTTPLAMARTLKKLLLDDGLPPAQRQ +QLKDWMVGNTTGDTRIRAGAPKGAMVADKTGTSGYGVANDIGVVWVPDRAPVVVVVFTHS +MDKAAEARSEIVAAATRVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=P95675_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASRTLT-AWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLRTVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRNVLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 769 TaxID=1262452 RepID=A0A0A8ECN3_9ACTN +-----GEFKKLERKFDARLGVYAIDTGTGREV-AYNDAERFAHASTFKALAAGAVLRKYA +--PSGMDKVIKYSKDDLVDYSPVTEKHVETGMTLRELCDAAVRYSDNTAGNLLFDALGGP +KGLNATLKEIGDDATRMERREPELNRWAPGEQRDTSTPRALAKDLRAFVLGNVLGKGERA +QLAKWLQTNTTGAELIRAGMPKDWKVGDKTGAGSYGTRNDIAVVWRPDAAPIVVAIMSNR +STEDAHYDNKLIAEAASVVAH-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02400 TaxID=1703944 RepID=A0A1Q5M7D5_9ACTN +------SLTDLEREYGARLGVYALATGTGATV-VHRADERFALCSTFKTLAAAAVLDRHP +--VTRLDRRVTYTRADLVAYSPVTEKHVGTGMSLRDLCDAAVRYSDNTAANLLLRELGGP +RALTAHLRGLGDRVSRLDHDEPELNSNPPGDPRDTTSPRAVAADYRALVLDDALPAAKRE +LLTDWLVRNTTGDLRVRAGVPRDWKVGDKTGTGDWGRANDVAVLWPPRGAPLVIAVLTER +PDRGADPSDALVAEATRRVL--- +>[subseq from] Beta-lactamase n=1 Tax=Jishengella endophytica TaxID=515350 RepID=A0A2W2CJX9_9ACTN +------DFAPLEGEFDARLGVYALDTGTGRTV-AHRPDERFAYASTFKALAAAAVLADTS +--TEELDQIVKYSRDDLVTYSPITEQHVETGMSLRAIADAAVRYSDNTAGNLLLDRLGGP +AGFQQVLRDIGDEVTEPARWETELNEATPGDTRDTSTPRALATSLKTYAVDDALTAEDRA +VLVDWLKGNTTGDKTIRAGTPDGWQVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAVLSSR +SDKDAERDDALLARATELTL--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A243IMP3_BACHU +--ATHREFAQLEKQFDARLGVYAIDTGTNRTV-SYKHNERFAFASTYKALAAGAVLQQNS +--IDELDKVITYTKDDLVAYSPITEKHVDTGMTLGEIADAAVRYSDNTAGNLLFKELDGP +KGFEKVLRQIGDKITHADRFETDLNEATPGDIRDTSTPKALATDLKAFTVGNALPADKRK +ILTDWMSGNATGDKLIRAGVPQDWVVADKSGAASYGTRNDIAIVWPPNRAPIIIAILSSR +DKTDATYNNELIAQAATVTVN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rubrivivax sp. TaxID=50259 RepID=A0A519Z4S6_9BURK +---AEDLLAQLETASGGRLGVAAFDVANNARI-LHRAEERFPLCSTFKVIAVSAILSRST +KDDALLKQRVAIESSEVVANSPITGKHVGAGMSVADLCAAALQYSDNTAANLLVKLLGGP +SAVTAFARLAGDDTFRLDRWETELNSAIPGDPRDTSTPANMARSLQGLALDNVLADPQRD +QLQAWLKGNTTGAARIRAGVPSDWVVGDKTGAGAHGTTNDIAVLWPTQGSPIVLAIYFTQ +PDKNAPMRNDVIADASRIVVD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI00111FD723 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A443G660_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1S9XHN4_BACMY +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIAEATKIVLD-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Chryseobacterium gallinarum TaxID=1324352 RepID=UPI00143CE137 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQ------------ +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella aerogenes TaxID=548 RepID=UPI000E04CF54 +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ +LLLQWMVDDRMAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9AEN8_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS094611 TaxID=2033516 RepID=A0A2A7DZP0_9BACI +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLIEIGDTVTNPERFEPELNEVYPGEIHDTSTPKALATSLQAFALGDILSTEKRN +LLIDWMKRNTTGDKLIRAGVPEGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1S9XE94_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-TYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIADAAEVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A649UIG8_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGVVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTTFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEH- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. ABP14 TaxID=1892404 RepID=UPI0011A3E474 +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLIEIGDTVTNPERFEPELNEVYPGEIHDTSTPKALATSLQAFALGDILSTEKRN +LLIDWMKRNTTGDKLIRAGVPEGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobacter sp. Root29 TaxID=1736511 RepID=A0A0Q6M020_9BURK +------RWAAIEAESGGRLGVAVLDTANGQVD-GHRLDERFPMCSTFKWLAASLALQRVD +AGLERLDRRVAVRREMLVSNSPVSEKHVGGDMSIAELCEAAVLVSDNAAANLLLASFGGP +AAITRHARSLGDMKTRLDRTEPALNEARPGDPRDTTTPHAMAIALRSALLGTALSDASRA +RLVQWMEAVRTGVDRLRAGVPPGWRVADKTGTGARGSTNDVAVIWPPQRAPLVVTAYLTD +SKADAARRNAALAAVAREAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. (strain BR816) TaxID=1057002 RepID=UPI0003805C7E +--DVTSRLAALEKRTGGRLGVAVLDTETNISF-GHRQTERFAMCSTFKALAAACALARVD +RGEEKLERRITFGKDVLLPHSPVTEKYAGGNMTVAELCDAAITISDNAAANLLLESFGGP +AGLTAWLRSIGDKTTRLDRTEPDLNEAKFGDPRDTTTPAAMLETLGKLAFGSVLSEGSRQ +QLVEWMVANTTGDARLRAGLPGDWRIGDKTGTSSTGAVSDIAFAVPKGRGPILISVYTGE +ATVKPAELNPVFAEVGKIVA--- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI00084CB3D2 +-----EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTTFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Class A beta-lactamase n=1 Tax=Xylophilus sp. Leaf220 TaxID=1735686 RepID=A0A0Q4H1E5_9BURK +--EARAAFARIETAADGRLGVCAFRTDGGPVV-QHRAQERFPACSTFKTLAAAAVLARSD +AVPGLMDRVVRYGPADLVNYSPVTSKQVGEGMTYAALCAAALQYSDNTAGNLLLREIGGP +EGLTRYARGLGDTEFRLDRWETALNDAVPGDPRDTCTPGGMARNLQRLLLGDALAPAHRA +RLTEWMRGNTTGGARIRAGVPAGWPVADKTGSGDYGTVNDIGVAWPPAGSPLVIAVYFTR +AVPDAPLRHDVVADAARAVVR-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0009BF1371 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRSGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. R72 TaxID=1764278 RepID=A0A246U819_9RHIZ +-dEINRRMDALEKAIGGRIGVSAIDTDTNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQETLERRVVYEKDKLVTYSPETEKHVGGEMSLSELCQAAITLSDDTAGNLLLESFGGP +AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTQGSALSEPSRD +KLIEWMVANTTGGARLRAGLPDTWKIGDKTGTANNGSAADIAVIWPPGHGAILVAAYVTQ +AKAPVSEINPVFAEVGKIVAD-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001082A507 +-----EQIKISEGQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGGRGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000159752D +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus tropicus TaxID=2026188 RepID=UPI000BF79145 +-qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPITEKHIDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMSDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000E2DB95C +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAVTLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. 7MK8-2 TaxID=2419777 RepID=A0A494X6L9_9BURK +--QIEARLAQIEREVDGRLGVAIYDSASGLTA-GHRMHELFPMCSTFKFLAAAAVLARVD +RREEDLARRIMYARSDVVIASPATEKHTDTGMTMGELCEAAITLSDDTAGNLLLASFGGP +AQLTAFVRQLGDTVTRLDRNEPTVNEAIPGDPRDTTTPIAMLADMRNVLLGDVLTAQSRA +QMIAWLVGCQTGGAKLRAKLPKDWRVGDKTGGGEHGTHNDIAIMWPPERAPIFVAAYLTQ +TDAPFARCDAALADVGEAVAS-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42) TaxID=326423 RepID=A7Z3J5_BACVZ +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Catellatospora sp. H14505 TaxID=1969805 RepID=UPI001183A4E9 +---AATAFADLETRFDARLGVYAIDTGTGRTV-EHRADERFAYASTFKALAAAAVLDTTT +--AEQLDRVVHYTDADLVTYSPVTEKHVQTGMSLRDLADAAVRYSDNTAGNLLLDHLGGP +DGFEKALRGLGDQTTDVARREPELNQATPGDTRDTSTPRALVDDLRAYTLGDGLADDDRT +VLNDWLRGNTTGAKLIRAGVPAGWQVGDKTGAAAYGTRNDIAVIWPTDGAPIVLAILSSH +DEQDAKYDDALIAQAAAAAI--- +>[subseq from] BBI family class A beta-lactamase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI000D112268 +---MDIKFAALENKFDARLGVYAIDTETDLAV-AYRQDERFAFASTYKALAAGAVLHQKP +--LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP +KGFESALRQIGDSVTTSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGDVLPSDKQT +ILIEWLQGNTTGDKLIRAGLPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR +DKQDATYDDALIAEATKVAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Aureimonas ureilytica TaxID=401562 RepID=A0A175R6F5_9RHIZ +--DLDALWAEIENRFSARLGAFVWDMETDRRW-ARRADERFPLCSTFKLVAAAGLLARVD +AGQENLSRRVVIAKSDLVTYSPETEKHVGGEMTLSSIAEAALTQSDNTAGNVLIDLLGGP +EGVTRTARGFGDESFRLDRRETALNEAKPGDPRDTTSPAAMTKTLHALLFGEALKPDSRR +QLADWMVANRTGDAKLRAGLPKDWRVGDKTGGGDFGTMNDVAVIWPPAGKPILISLYLTE +TKASFDERNAAFAEVGRAL---- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. 17Sr1-1 TaxID=2202826 RepID=A0A2U8X864_9RHIZ +--DTVARLAQLERRDGGMLGVEVRDTATGRRF-GHRADERFPMCSTFKAIAAAAVLARAD +AGKDDLNRRIAYGRDALLSYAPVTTKHVETGMTLAELCAAAVVWSDNTAANLMLDTLGGP +GGITAFARAHGDTVTRLDRTEPTLNTAIAGDVRDTTSPAAMVGLLENVLLGRALSAESRA +RLIGWMHDSPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG +SPAEPAARDALHAEIGRLIAR-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0007ABDA07 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEMAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=A0A5Q3KQ94_9BACI +---TNKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces formicae TaxID=1616117 RepID=A0A291QG68_9ACTN +--DVRRRLRELEKGYPGRIGVHALHTGTGATV-GYRADERFAIASTFKVLAGAAILRRAR +EEPGLLDVLIRYGRDDLVTHSPRTEMHLETGMTVRELCDATITYSDNAAANLLMRRIGGP +SGITEFARSIGDSRTRLDRWETDLNTNIPGDRRDTTTPAAMTENLRKLVIGDALHPLDRD +QLIRWLLENTTGDQRIRAGLPEGWRVGDKTGSPAYGGVNDVAVAWPPKGAPLVVSVYTTR +LDPDTPGEDRIAEDITRIVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola pv. corylina TaxID=487821 RepID=A0A2S7CG57_9XANT +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIHNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPSAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacter henricii TaxID=69395 RepID=UPI0011A8A998 +----SRSIVALEARSGGRLGVAVLDTANGKTF-TYRGDERFAMCSTFKALVAGLVLKRVD +QGQERLDRRIPYGPGVLLAHSPATEKHVGQGMTVGALCEATVTLSDNAAANLLLHTFGGP +PALTAFLRGLGDTVTRLDGYEPGLNVVRPGEIHDTTSPSAMLATLRALTLGPVLSAASRQ +QLVAWLVANQTGDKRLRAGLPAGWKVGDKTGSWSVGTTNDIAVTWPPGRPPLLITAYLSR +STLDDDGRNAVIAEVARLVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus wulumuqiensis TaxID=1567107 RepID=UPI0006197A67 +---VVTSLKHLEQQHKGRVGVYAVDTGTGRVV-AYRHNERFAFASTYKALAAAAVLQQSS +--ISDLDRVITYSADDLVEYSPITEKHVETGMTLREICLAAIQYSDNTAGNILFQELNGP +AGFQQALRQIGDTVTRSERIEPELNEIVPGDSRDTSTPRALARDLRLITTGKVLTQDKRQ +LLTEWMKGNTTGDQLIRAAVPKGWVVGDKTGSAAYGTRNDIAIIWPPDRAPIIMAILTDH +DDKDAKTDNELVAKAARITLK-- +>[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=I1YAX3_ECOLX +-------------------GYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Class A beta-lactamase n=1 Tax=Desulforhopalus sp. IMCC35007 TaxID=2569543 RepID=A0A4V5NS63_9DELT +-pGLTETIQQIEKNLDARIGVAVYEEGTGRNW-QYHADDRFPMSSTFKTLACSTLLSRVD +AGQEKLDRSVVFEEKDLVTYSPVTKTRVGASMSLSELCEATMSMSDNSAANFILRNIGGP +EAVTTFVRSVGDTITRLDRWEPDLNEATPGDVRDTTTPNAMVQTLKSLVFGDTLNLRSRE +QLINWLKGNKVGDALFRAGVPSTWVVADKTGAGGHGSRSIAAIMWPPKSQPIIATVYITE +TEATFDARNAAIAEIGEVIAR-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. C5 TaxID=2035448 RepID=A0A2A6JGF4_9RHIZ +--NVERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGEEKLDRRVTYGRDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGGERLRAGLPQEWKVGDKTGTGPNGSLGDIAVIWPPDRGPIAAAVYIAE +ATVPVKDLNPIFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. J33 TaxID=935836 RepID=UPI0004B08B11 +---IEEAFTQLESKFDARLGVYAIDTETEKSI-AYRADERFAFASTYKALAAGAMLKQKS +--LNDLDEIITYTKDDLVTYSPITEKHVDTGMSLRDIADAAIRYSDNTAGNLLLKELGGP +AGFETALREIGDKVTESDRFEPDLNFTVPGDSRDTSTPRALATSLQAFAASDLLPSEKRA +LMTDLLVGNTTGDTLIRAGVPEGWVVGDKSGAGTYGTRNDIAIVWPPNSDPIIIAILSDR +STEDAAYDDALIAEAAKIVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=A0A0P0IBD9_KLEVA +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMSATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. SYJ TaxID=2529386 RepID=UPI000B43EF9D +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKDLTVRNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIAEAAEVVVNAf +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007F910AE +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTALPSYPRDATAARGMAQTLRNPTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0012AC02A6 +----NQKFVQLEKKFDARLGVYAIDTGSNQTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus vallismortis TaxID=72361 RepID=A0A1W6HH11_BACVA +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF9E835 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=8 Tax=Bacillus TaxID=1386 RepID=A0A5B2T408_BACCE +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF7E4FF +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFA6778 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILTNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0005CE21C6 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Roseomonas TaxID=2617492 RepID=A0A1Q2YQ29_9PROT +---LPAVFAGIERRVGGRLGVAVLDTATGQRA-GHREAERFPLTSTFKLLAAAAVLSRVD +AGQARLDQRIRYGREKLVAYSPETEKHAGEEMTLAAICEAAVTLSDNTAGNLMLEQIGGP +AGLTAWLRSIGDTVTRLDRWETALNEAEPGDPRDTTSPAAMLASLQRVTLGEALSVGGQA +HLTGWLRANKTGDKRLRAGLPGGWQAGDKTGAGERGTNNDAGLLWPPGEAPILVAAYSTG +GTAPSTERDAALAEVAAAIVA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus sp. LUNF1 TaxID=2709781 RepID=A0A6C1CMU7_9BACI +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora humi TaxID=745366 RepID=A0A1C5JNY2_9ACTN +----DREFRRLEQEFDARLGVYAVDTGTGRTM-GYRADERFAYASTFKALAAAEILDETT +--DAELDKVVRYSADDLVTYSPITEQHVDEGMTLRAIADAAVRYSDNTAGNLMLRRLGGP +QKFEKELREVGDKVTDPARWETDLNEARPGDRRDTSTPRALAGSLRAYAVGDALEPADRD +VLNGWLRGNTTGAELIRAGVPDGWVVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEKDAEYDNALIARATEVALAGw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI00128FB05C +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD592E8 +-dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +KGDESLDRRITYGRDKLVTYSPETEKHAGGDMTMAEICKAAITLSDNTAGNLMLESFGGP +AALTDWLRSIGDGTTRLDRMETALNEATKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN +QLIDWMIANTTGGARLRAGLPGDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYIGE +ATVKMDEFNPVFAEIGKMITE-- +>[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella quasivariicola TaxID=2026240 RepID=UPI001181F252 +-----EQIKISESQLSGRVGYVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVERLDRRIHYRQQDLVAYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLDTLGGP +AGLTAFLRTIGDNVTRLDRRETQLNEALPGDVRDTTTPASMAATLRKLLTAKHLSARSQQ +QLVQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYMRD +TPATIAERNQQIAAIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000D663E90 +----NQKFVQLEKKFDARIGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVALN-- +>[subseq from] Putative carpapenem-hydrolyzing beta-lactamase KPC-14 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=K4NUK1_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGV-YANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE57A77 +-nDIEKQLAALEKRTGGRLGVFVLDTKNNVSF-AHRPDERFAMCSTFKALAAAFVLARAD +MGEEKLDRRIPVSKKDLLSYSPVVEKHVGDGMTVRELCDAAVTYSDNAAANLLLASFGGP +KGLTTWLRSIGDLTTRLDRTEPELNEAKVGDPRDTTTPMAMTETLGRLLLQDVLSPSSRE +QFAAWLVANTTGDRRLRAGLPQDWTIGEKTGTSGRGEAGDIGFMRPRDGHTILASVYIAE +GKKPTKELEPVFADVGKLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. BSE7F TaxID=2175092 RepID=UPI000D6104C8 +------SLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP +--GARLDERITYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAANLLLRDIGGP +RGVTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVLGDALPAAGRA +LLTDWLVRNKTGDRRIRAGAPRGWRVGDKTGSGDWGRCNDVAVLWPGGGPPLMLSVLTER +PDRAASPSDELVAEAARRVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Raoultella sp. BIGb0399 TaxID=2485119 RepID=A0A3N2EV52_9ENTR +heATISRVKTAESQLQGRVGYAELDLTTGRLLaGYRADQRFPMMSTFKVLLCGAVLARVD +SGEEKLDRRIHYRQQDLVEYSPQTEKHLDDGLTVGELCAATITLSDNTAANLLLTAIGGP +QGLTAFLRRSGDRTSRLDRREPELNAAVPGDVRDTTTPQAMATTLRRLLTGGVLSASSQQ +QLQRWMIDDQVAGPLLRASLPSGWFIADKTGAGQRGSRGIIAALGPDGKPSRIVVIYLTD +TDATMAVRNQQIAEIGATLVENw +>[subseq from] Beta-lactamase n=3 Tax=Hydrogenophaga TaxID=47420 RepID=A0A1L1P864_HYDIT +--ELDAAVRELESQSRGRLGVHFIDTGDGREW-GYRSDERFLMLSTFKTLASALVLERAD +QGKAPLSKRVRYHQRDLVQWSPVTEKHVGGQLSLAQLCEATITTSDNTAANLILREVGGP +AALTAFLRRIGDPVTRLDRTEPELNEPSPGEDLDTTTPRAMARSLRTLLLGEALSPASRE +QLAAWLKANTTGDKRLRAGVPPSWGIGEKTGTAGP-SANDAGIVWPPGAAPILVSAYLAD +SPASAAVRERTLAGVGRLLA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZR62_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSXI-LYRADERFAMCSTSKEMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAE----------------- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia rohdei TaxID=29485 RepID=UPI00061CCFD1 +--SLDKQLAELEQQSQGLLGITVINTGNGRKI-QYRGTQRFPFCSTFKFILAAAVLNKSA +SQPKLLDKHLHYHERDLLSYAPITRKNLAHGMSVSQLCAATVQYSDNTAANLLIQELGGV +ESVNQFARSIGDQTFRLDRLEPELNSALPNDPRDTTTPSAMAASMNALVLGDALPAAQRE +QLAVWLKGNTTGGETIRAGAPAEWIVGDKTGTGDYGTTNDIAVLWPTKTAPIVLVIYFTQ +REKDAKPRRDVLAAATKILLSH- +>[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. JE062 TaxID=439495 RepID=UPI00055DF5C9 +--ELLDTVNRLENEVGGRIGVVLQHTGSDWAI-ESRADERFPMASTFKALLCGAVLARVD +RGEERLGEVVAYSKAELVSYSPVTKKHVAEGMRVGELCEATVTMSDNTAANLLLKRVDGP +KGLTRFLRGLGDRVTRLDRREPEMNEAKPGDARDTTSPRAVVQTLDRLLFEEVLQPSSRA +QLQQWMVDDKVADALIRKHLPSDWRIADKSGAGHNGSRGIIAAIWPETGEPYLAAVYMTG +SDANFKKRNAVIAEIGKAIIE-- +>[subseq from] Beta-lactamase n=1 Tax=Lysobacter sp. yr284 TaxID=1761791 RepID=A0A1H3PNL6_9GAMM +--ALRAKLAELEKRSGGRLGVSALDSGDGRRF-DVRGGERFAMCSTFKFLLSAAVLHKVD +RGDLDLQQRIAVPKSALVPHAPFTGPLAEAGASVAQLCEATMTLSDNPAANLLLPLVGNP +DGLTRFLRGIGDPTTRLDRNEPELNTAIPGDPRDTTSPNAMLASMRALLLGDALSAASRT +QLADWLIANKTGDKRLRAGLPKDWRIGDKTGSGN-GTTNDIAIVWPSGRKPVFIVTYLTQ +ATGEDEQRSAILADAARALFEHw +>[subseq from] Beta-lactamase n=2 Tax=Acetobacteraceae bacterium AT-5844 TaxID=1054213 RepID=H0A5X7_9PROT +-----ATFARIEAERGGRLGVAVLDTGSGRKA-GHRVDERFPMGSTFKTLASAAILARVD +AGKESLQRRIRFSRADLVTYSPVTEKNVGGDMTLAALCEATITTSDNTAGNLLLNALGGP +AALTAWLRSLGDNVTRLDRMETALNEARPDDPRDTTSPSAMAADIHALTLGEALSQGSRQ +QLIRWLRDNKTGDARLRARLPAGWTAAEKTGTSGNNTSNDVGLLFPPGGAPIVVAAYLTQ +GAAKGAIRDAALADVGAAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. S-93 TaxID=2653122 RepID=UPI001260437A +--DVDKQLADLEQKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE +ATAPAKDVEAVFAEISKIVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. BK100 TaxID=2512181 RepID=A0A4R1ZW83_9BACI +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALANDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodospirillaceae bacterium TaxID=1898112 RepID=A0A5C7NPY1_9PROT +--RLQAELAKIEASSGGRLGVAIRDTAIGMTV-GHREKERFPICSTFKFLAAAAVLKRVD +MHQENLDRRIVFSRKDLVHYSPVTEQRTGGEMTVAEICDAAVAMSDNSAGNLLLRSLGGP +SGITLFTRSLGDNMTRLDRWETDLGEATPGDPRDTTTPASMLNNLQKLLVKTTLSEPSQA +QLLEWLVACKTGDNRLRAKLPKDWRVGDKTGSGNHGSANDVAILMPPDRAPILVTVYLTQ +TDASPSDRDAAIAEVGHLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Yersinia rohdei TaxID=29485 RepID=A0A0U1HQ02_YERRO +--SLDKQLAELEQQSQGLLGITVINTGNGRKI-QYRGTQRFPFCSTFKFILAAAVLNKSA +SQPKLLDKHLHYHERDLLSYAPITRKNLAHGMSVSQLCAATVQYSDNTAANLLIQELGGV +ESVNQFARSIGDQTFRLDRLEPELNSALPNDPRDTTTPSAMAASMNALVLGDALPAAQRE +QLAVWLKGNTTGGETIRAGAPAEWIVGDKTGTGDYGTTNDIAVLWPTKAAPIVLVIYFTQ +REKDAKPRRDVLAAATKILLSH- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00102EBB88 +--ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNKRFAYASTYKALSAGAVLQQNS +--IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLNGP +KGFEEALRQIGDKVTVANRFETDLNEAIPGDIRDTSTAKTLATDIKAFTVGNALPADKRK +ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR +DKKDATYDNELIAQAAKVTIN-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHY5_KLEPN +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMVERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF5BB78 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGNNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVVAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI001047BFDD +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALANDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Gluconobacter wancherniae NBRC 103581 TaxID=656744 RepID=A0A511B0D5_9PROT +--DVHRKLAWIERKSGGRLGVCAYLSGTTRPAvTYRGGERFPMCSTCKALLSAAVLARVD +RGRESLSRKILIRPQDLMHYSPITQPHIGTALTLGDMCSAAVSYSDNTAANALLRVLGGP +AMVTAFARSIGDTVTRLDRWEPALNEALPGDPRDTTTPEAMSRNLTQLLSGDALSSASRR +TLLEWMVANQTGDARIRAGVPKSWRVGDKTGTGSRGTINDIAFIMPPEKTPFALSIYLTG +SPLSANAGNAIIAEIARTIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=D5LIR5_ENTCL +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELRAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGTGAAPIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae 30660/NJST258_1 TaxID=1420012 RepID=A0A0E1CLX4_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRGT-ELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1G4L6J3_BACCE +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI00119EEEE5 +----NQSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +NEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. LP_7_YM TaxID=2485137 RepID=A0A4R7WV13_9PSED +---IEQQLAELELRHGGRLGVAILDTGSQRLI-THRGDERFALCSTFKALAVAHVLARVD +RKEEDLSRLIVYGKDQLVTYSPVTEKHAGNPLSVGSICEAAITLSDNTAANLLLDSFAGP +EGLTDWLRSMGDQTTRLDRREPELNENRPGDLRDTTTPVAMLQSLRTLVLGNALSAASRD +QLVAWLGSNKTGDQKLRAGLPKGWRVGDKTGLGANNASNDVAVIWPSERAPLIVTLYSTG +SHANAEQINALMADVGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000C75AAF4 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0011ACA0E0 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +VLTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF918F5 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPEGWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. LP_7_YM TaxID=2485137 RepID=UPI0010611361 +---IEQQLAELELRHGGRLGVAILDTGSQRLI-THRGDERFALCSTFKALAVAHVLARVD +RKEEDLSRLIVYGKDQLVTYSPVTEKHAGNPLSVGSICEAAITLSDNTAANLLLDSFAGP +EGLTDWLRSMGDQTTRLDRREPELNENRPGDLRDTTTPVAMLQSLRTLVLGNALSAASRD +QLVAWLGSNKTGDQKLRAGLPKGWRVGDKTGLGANNASNDVAVIWPSERAPLIVTLYSTG +SHANAEQINALMADVGRLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. R635 TaxID=1764275 RepID=A0A246TBV4_9RHIZ +--NIEHRLAALEKRTGGRLGVSVLDTQTSISF-GYRGGEAFPMCSTFKALAAGFVLARVD +KGEESLDRRVSYGKEKLVDYSPVSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +PALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSILTEASCN +RLIAWLVASTTGKERLRAGLPQDWKAGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +AIVPAKELNPIFAEVGRMIAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Burkholderia sp. YR290 TaxID=1882799 RepID=A0A2C8Y6M9_9BURK +--ALEKQLAQIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD +RGKEQLGRTIVYSKEAVVANSPVSGPRAGDDMTVAELCEAAITRSDNTAANLLLDSIGGP +AALTAFARGIGDRITRLDRNEPTLNEATEADPRDTTTPAAMLADMRALLLGGHLSAASRE +QLTAWLAGNKTGDARLRAGLPKAWRVGDKTGTGERGTSNDIAVIWPEGRAPILVAAYLTG +ATATSTQRDAAIAQVGALVAN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0009B510BA +-qATHKEFSQLEKKFEARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYENALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAKNLKDFTVGNALPDYKRK +VLTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIVAILSSK +DEKEATYDNQLIAEATEVVVN-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium tibeticum TaxID=501024 RepID=A0A1H8FXD3_9RHIZ +-dEINRRIGALEKAIGGRIGVSAIDTQTNISF-GYRETERFPLCSTFKVLAAGLVLARVD +KGQDTLERRVVYDQAKLVTYSPETEKHVGGEMSLSELCEAAITLSDNTAGNLLLESFGGP +PELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLALGSALSEPSRD +KLTEWMVANTTGGARLRAGLPGTWRIGDKTGTGNNGSAADIALVWPPGHGAILVAAYVTQ +ARAPLSEINPVFAEVGRIVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacilli bacterium VT-13-104 TaxID=1637974 RepID=A0A0K0GDZ5_9FIRM +--KIDNQFSQLEEEFDAELGVYAVDTETNQAI-EYQSEERFAFASTYKALAAAIVLQQNS +--MEELNQVITYTKEDLVPYSPVTEKHVDSGMTLLNLAEAAVRTSDNTAGNLLFNAIGGP +KEFEQTLREIGDNDTQAERYEPDLNQFSPEDPRDTSTPKALATSLQAFALGDLLPNEKRE +QFTDWLQGNATGDTLIRAGAPEGWEVGDKSGAGSYGTRNDIAVVWPPNREPIVIAIMSRH +DTEDATYDDALIAQAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. LS-2 TaxID=2315859 RepID=A0A3A6RM48_9PSED +--SIEAQLAALELRHGGRLGVAILDTGNQRLV-SHRGEERFALCSTFKALAAAYVLARVD +LKDEDLSRLIVYGQDQLVTYSPVTEQHAGEGLSVGSICEAAVTLSDNTAANLLLDSFGGP +PGLTAWLRSIGDQTTRLDRHEPELNENRPGDLQDTTTPIAMLQSLRTLLLGEVLSGASRD +QLSAWLASNKTGDQKLRAGLPKGWRVGDKTGSGSNNASNDVAIVWPTDRPPLIVTVYYSE +SKATSEQINSLMAEVGRLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BEE1A58 +----KHHFVKLEDKFDARLGVFALDTSTNQTV-TYRADERFIYASTSKALAVGALLQQKT +--IDDLNQRITYTQDDLVNYNPITEKHVDTGMTLKELCDAALRYSDNTAMNLILKQIGGP +NGLEKSLRDVGDNVTMPEQFEPELNDVKPGETHDTSTPRALATSLQSFTLGDVLPIEKRE +LLIDWMKRNTTGDSLIRAGVPKGWVVADKTGSGSYGTRNDIAIIWPPKGDPIMLAILSSR +DKKDANYNDKLIAEATKEVINAy +>[subseq from] class A beta-lactamase n=1 Tax=Hydrogenophaga sp. PML113 TaxID=1899350 RepID=UPI000879024D +--ALDAAARALEAKSRGRLGVHILDTADGREW-GHRSDERFLMLSTFKTLAAALVLRRTD +QGKAPLSKRVRYRQRDLVQWSPVTEKHVGGRLSLAQLCEATITTSDNTAANLILREVGGP +AALTAFLRGIGDPVTRLDRMEPELNEPSPGEDLDTTTPRAMARTLRTLLLGDALSPASRE +QLAAWLKANTTGDRRLRAGVPPIWGIGEKTGTAGE-SANDAGIVWPPGRAPLLVSAYLAD +SPAGAAAREQALAGVGRLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00099C0B9F +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSNKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A2B8JYJ1_BACME +----KHHFVKLEDKFDARLGVFALDTSTNQTV-TYRADERFIYASTSKALAVGALLQQKT +--IDDLNQRITYTQDDLVNYNPITEKHVDTGMTLKELCDAALRYSDNTAMNLILKQIGGP +NGLEKSLRDVGDNVTMPEQFEPELNDVKPGETHDTSTPRALATSLQSFTLGDVLPIEKRE +LLIDWMKRNTTGDSLIRAGVPKGWVVADKTGSGSYGTRNDIAIIWPPKGDPIMLAILSSR +DKKDANYNDKLIAEATKEVINAy +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0006680D59 +-----EQIKISEGQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q6ZY76_KLEPN +-----EQIKISEGQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI001440FE84 +--NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGDESLDRRVSYGKDKLVDYSPISEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAILDTLGNVTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVKDLNPIFAEVGKMITE-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudovibrio sp. JE062 TaxID=439495 RepID=B6QWS2_9RHOB +--ELLDTVNRLENEVGGRIGVVLQHTGSDWAI-ESRADERFPMASTFKALLCGAVLARVD +RGEERLGEVVAYSKAELVSYSPVTKKHVAEGMRVGELCEATVTMSDNTAANLLLKRVDGP +KGLTRFLRGLGDRVTRLDRREPEMNEAKPGDARDTTSPRAVVQTLDRLLFEEVLQPSSRA +QLQQWMVDDKVADALIRKHLPSDWRIADKSGAGHNGSRGIIAAIWPETGEPYLAAVYMTG +SDANFKKRNAVIAEIGKAIIE-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sediminicola TaxID=458836 RepID=A0A3R7E0T2_9BURK +--AIRQRLAQIEVESGGRLGVSILDTTSGLHA-GLRTDERFPMCSTFKLLAAGLVLTRVD +RGQEDLERCIVFSKSDLMPYSPATSEHTRERMSVADLCKAALTLSDNTAANLLLASFGGP +AALTAFARSIGDGVTRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELLLGERLSSLSRA +QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDIAILWPPGRGPILVTVYLTE +TSGDAARCNAAIASVGALVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium mesoamericanum STM3625 TaxID=1211777 RepID=K0PE23_9RHIZ +--DINRRMDALEKAIGGHIGVSAIDTDTNISF-GYRETERFPICSTFKVLAAGLVLARVD +KGQETLERRVVYEKDKLVTYSPETEKHVGGEMSLSELCQAAITLSDNTAGNLLLESFGGP +AELTKWLRTLGDRSTRLDRWETALNEVKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD +KLIEWMVANTTGGARLRAGLPDTWKIGDKTGTANNGSAADIAVVWPPGHGAILVAAYVTQ +AKAPVSEINPVFAEVGKIVAD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI00099244DA +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRSGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] Beta-lactamase n=6 Tax=Bacillus TaxID=1386 RepID=A0A2A7CHS8_BACCE +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKHDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. VMFN-A1 TaxID=2135607 RepID=A0A2V1ZAP8_9BACI +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SMS_SU21 TaxID=2069440 RepID=A0A2U2EX30_9ACTN +------SLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP +--GTRLDERITYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAANLLLRDIGGP +RGVTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVLGDALPAAGRA +LLTDWLVRNKTGDRRIRAGAPRGWRVGDKTGSGDWGRCNDVAVLWPGGGPPLMLSVLTER +PDRAASPSDELVAEAARRVLD-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI001033E322 +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella quasipneumoniae subsp. similipneumoniae TaxID=1463164 RepID=A0A455LWB5_9ENTR +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000D16A7BD +--ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRTSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMVDRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F615_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVAIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B2GRM4_BACCE +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSERFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWEVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000C228E44 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYDNALIAEAAKAALN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=A0A6A8LHP4_9BACI +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI00100ADA6F +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYDNALIAEAAKAALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000B44776F +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI000BA60ED6 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000D6AF686 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI001039783B +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00118657E4 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A4Q9YFA7_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRSGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVVIN-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI001033F4B6 +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRLIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI00046EC1EC +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0005187735 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI001118123A +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMQGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI00128F8CE7 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. NRRL B-16802 TaxID=1415541 RepID=A0A0N0TN39_9ACTN +----DHEFRRLEERFDARLGVYAIDTGTGRTV-QYRADERFAYASTFKALAAAEVLDETT +--DAELDRVVRYSADDLVTYSPITEQHVADGMTLRAIADAAVRYSDNTAGNLLLRQLGGP +QKFEKELREIGDKVTDPERYETALNEAKPGDRRDTSTARALAGSLRAYAVGDALESADRD +ILNGWLRGNTTGDELIRAGVPDGWVVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEKDADYDNALIARATEVVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Polaromonas sp. CF318 TaxID=1144318 RepID=J2LB99_9BURK +--SATRRLAAIEKTSGGRLGVSILDTGSGAKY-GYRAGERFPMCSTFKLLAAALVLHRVD +AGQEQLDRRIPIAAGDILPHSPTTQQHIGPQLPMAALCEASIIVSDNAAANLMLASFGGP +DGLTTYLRGLGDKMTRLDRTEPELNESAPGDVRDTTTPDAMLATVHKLTLGSALSDASRQ +LLVQWLQANTTGDRRLRALLPPGWRVGDKTGTGAHGSTNDVGLIWPPGRPPLLVAAYLTG +TQQPAAQRDVALAKVGQLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI00049836B4 +--ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS +--IDKLDEVITYTKDDLVEYSPITEKHMDTGMTLGEIAEAAIRYSDNTAGNLLFKKLDGP +KGFEKALRQIGDKVTMADRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPTDKRK +ILTDWMRGNATGDKLIRSGVPKDWEVDDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR +DKEDATYDNELIAQAAKVTIN-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Verrucomicrobia (miscellaneous) TaxID=417295 RepID=A0A1Q6V7G7_9BACT +--DAADQIAAIEARLGGRIGVAGLDTGNGKRI-DYRAEERFPLCSTFKFLAAAAVLKRVD +EKKDKLDRFVSYDAKDILEYAPVTKAHLGNGMTLGALCAAAIEQSDNTGGNLLLEAIGGP +VGLTNFARDLGDRMTRLDRKEPELNSAIPGDDRDTTTPASMLGDIRQLLVGNTLSASSRQ +QLQEWLQANETGAAMIRAGIPTNWIVGDKTGRGANGATNDVAIVHPPDRAPILLAIYCVG +STASANDRAAAVAEAAKVVAESf +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia kururiensis TaxID=984307 RepID=UPI000E0BFEEF +--SVRDALAALERTSGGRLGVCAIDTEGGRAI-GYRADERFAVCSTFKVVLAAAILARSL +DVPGLMQRRIRYTKQDLAHYSPVSSKHVRDGMTVAELCQAAIQYSDNTAANQLMKVLGGP +QAVTAYAHATGNTAFRLDRWETELNTAIPGDLRDTSTPAAMAHTLETLTVGQALPAAQRD +QLVTWLRGNTTGAHRIRAGVPGDWAVGDKTGTGDYGTTNDLAILWPPRRAPVMLAVYFTQ +REPKAKARDDVIAAAARIVA--- +>[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI0011A212D2 +-tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-TYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALATSLQAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPEGWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVVK-- +>[subseq from] Beta-lactamase n=1 Tax=Methylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2) TaxID=395965 RepID=B8EL76_METSB +--ELQGALADLEQKHGGRLGVAILDTATMRLI-ARRGDERFPLCSTFKFLAAAFVLARVD +RKEESLARRIIYASDVLVAHSPITGKYVGGDLTVGEICEAAVTVSDNTAGNLLLDSFGGP +AGLTAYVRSLGDNFTRIDRRETELNEAAPGDPRDTTTPLAMLEILHKTVLGTSLSAPSRQ +QMIAWLVANTTGGQRLRSGAPKGWRVGDKTGSGENNTTNDIAIIWPPQRAPLIVTAYYTE +ARASAVERDAVLSEVGRLAAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000BA63517 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=A0A411A4U6_9BACI +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Lentibacillus halodurans TaxID=237679 RepID=A0A1I0Y6W0_9BACI +--SITDDFAKLEDEFDARLGVFALDTGTNETV-TYRPDERFAYASTFKVLAVGALLQQKS +--IADLNQRITYTRDDLVNYNPITKKHVDTGMTLKELCDAALRYSDNTAANLILEQLEGP +SGLKKSLREIGDHVTEPARIEPALNEVKPGETHDTSTPKALADSLQAFTVGDVLPTEKRV +MLIDWMKRNTTGDTLIRAGVPESWEVADKTGAASYGTRNDIAIIWPPEGDPIVLAILSSR +DKKDAEYKDKLIAQATEEVID-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=A0A4V6F1F1_9BACI +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=A0A2I7TEY5_9BACI +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI001249B30D +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium laguerreae TaxID=1076926 RepID=A0A1S9H449_9RHIZ +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARTD +KGEENLGRRVSYGRDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTETSSD +RLIAWLVASTTGKVRLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPIFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000E22C3FB +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000BB769C3 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000AA07041 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=6 Tax=Bacillus TaxID=1386 RepID=A0A6C1WDG0_BACLI +-tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-TYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALATSLQAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPEGWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas formosensis TaxID=861534 RepID=UPI0012F75850 +-----DRFQILEKIGGGRLGVAVYDGETQRYN-GWRGHERFPMCSTFKLLAAALVLHRVD +RGVESLDRRVTYGQDSIVAYSPVTEQRIASGMTVGELCEAAITRSDNTAGNLLLASFGGP +PALTAFARRLGGGRTRLDRTETELNSALPGDRRDTTTPRDMVDMMRRLFFGRALSAPSRT +ILLGWLGANQTGARRLRAGLPSGWTIGDKTGTGDNGTANDVAILWPPGRRPMLIAVYLTQ +APGASASLDAIIAEVARTAT--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T9B8_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCRAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000CD585AD +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Stella sp. ATCC 35155 TaxID=2558175 RepID=UPI00113CCFCD +--ATAARLADLEARHGGRLGVSALDTGTGRRI-EHRADERFPMCSTFKLLAAACVLSRVD +RGEERLDRRVVFQASDLVAYSPATEKRVGGDMTMAEICAAAMTLSDNTAGNLLLASFGGP +PALTAYARSLGDRVTRLDRIETALNEGAPGDPRDTTTPGAMLDDLCALVLGTALSEPSRA +QLTTWLLDNRTGDRRLRAGFPGGWRVGDKTGTGGNGAAADVAVVWRPELPPLAVAVYWAE +ADVPFEGRNAIFEAVARIL---- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A1I4HKX1_9BACI +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYIDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001370DC69 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYIDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI0010334513 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPVVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE4FFAD +--DIEKQLAALEKRTGGRLGVYVLDTKTKVTF-AHRPDERFAMCSTFKALAAAFVLARVD +KGEEKLDRRIPISKKHLLSYSPVVEKHVGSGMTVGELCAATVTYSDNAAGNLLLASFGGP +KGLTDWLRSVGDETTRLDRIEPELNEAKIGDPRDTTSPKAMTETLGKLLLEDVLSPASRD +QFSAWLVANTTGDRRLRAGLPKGWIIGEKTGTSGRGEAGDIGFMRPAEGHTILASVYIAE +GKKKTKELEPVFAEVGKLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS075960 TaxID=2034282 RepID=A0A2B4LHF5_9BACI +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTI-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNLITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKSDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Dankookia rubra TaxID=1442381 RepID=A0A4R5QKH0_9PROT +---AAEALAALEARHGGRLGVAVLDTGSGQRL-AHRAGERFPLTSTFKFLAAGRVLARVD +RGEEGLDRMVAYTKADLVTYSPVTGQQA--AMSIGALCDAAVTFSDNTAGNLLLDSFGGP +AGLTAWLRGLGDAVTRLDRRETALNEARPGDPRDTTTPTAMLGLMQVLLLGEALAAASRA +QLAAWLVGCRTGDRRLRAGVPAGWRVGDKTGSGEIGTANDIGILWPPGRSPILVAAYSTG +SAAPEEARSAVLAEVGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus pseudomycoides TaxID=64104 RepID=UPI000BEBF425 +--ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS +--IDKLDEVITYTKDDLVEYSPITEKHMDTGMTLGEIAEAAIRYSDNTAGNLLFKKLDGP +KGFEKALRQIGDKVTMADRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNVLPTDKRK +ILTDWMRGNATGDKLIRSGVPKDWEVDDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR +DKEDATYDNELIAQAAKVTIN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A120EBT6_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRSGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000BA2C435 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIIWPPDRAPIVLAILSNR +FTEDANYDNALIAEAAKAALN-- +>[subseq from] Beta-lactamase n=2 Tax=Roseomonas gilardii TaxID=257708 RepID=A0A1L7AIX8_9PROT +---LPAAFAGIERRVGGRLGVAVLDTTTGQRA-GYRETERFPLTSTFKLLAAAAVLARAD +AGQARLEQRIRYGREKLVTYSPETEKHAGEEMTLAAICEAAITLSDNTAGNLMLEQLGGP +AGLTAWLRSIGDEVTRLDRWETALNEAKPGDPRDTTSPAAMLASLQRVTLGEALSDKAQA +HLSGWLRASRTGDKRLRAGLPAGWQAGEKTGAGERGTNNDTGLLWPPGGAPILVAAYSTG +STAPGTERDAALAEVATAIVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI000D6ADB69 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIIWPPDRAPIVLAILSNR +FTEDANYDNALIAEAAKAALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. AM1(2019) TaxID=2665175 RepID=UPI0013634C24 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000B8C692D +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHMDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000B8BDFF5 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYNNALIAETAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000C1C6927 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYNNALIAETAKVALN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia hospita TaxID=169430 RepID=A0A244DTI8_9BURK +--ALEKQLAQIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD +QGKEQLGRTIAYSKEVVVANSPVSGPRAGGDMTVAELCEAAITRSDNTAANLLLDSIGGP +AALTAFARGIGDRITRLDRNEPTLNEALEADPRDTTTPAAMLADMRALLLGEHLSAASRE +QLTAWLAGNKTGDARLRAGLPKAWRIGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG +ATATSTQRDSAIAQVGALVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. OV484 TaxID=1500308 RepID=UPI0006455538 +--ALNSRINDLEQRSGGRLGVAVLDTQTGRRF-AWRGDDRFRMCSTFKMPLAAAILRRVD +QGREQLDRRITYGRDVLMGNSPVVEKHLGEGMTVAALCEATITWSDNAAANLLLDALGGP +ASLTRFLRAIGDQTTRCDRREPELNTGAPDDPRDTTTPSAILGTWKTLLLDDALSPASRK +QLTAWVVANRTGDKRLRAGLPSGWRVGDKTGNNGKDTTNDIAIAWPRGRKPILIAAFHDR +GSADDDARSAVHADLARAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. YR710 TaxID=1882773 RepID=A0A1G6IF48_9SPHN +--DISTQLADLERQSGGRLGVAMLDCGNGRLV-GWRLDDRFPMCSTFKVMLAALILHRVA +IGEERLDRRIVVGTADLLSYAPVTSKYVGDPMTIEALCEAAVTMSDNTAANVLLTTSGGP +TALTRFARGIGDRETRLDRIEPALNEARAGDPRDTTTPAAMARSLRKLALGSALPADGRA +LLTRWLIGCRTGAARLRAGLPAGWAVGDKTGTGGRGSTNDIAVIWPTGRDPVIVAAYMTG +VTLGADAREAILASVGRLAAAQf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDFB569 +--DIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +KGDESLDRRVKYGKEKLVTYSPETEKHAGGDMTMAEICKAAITLSDNTAGNLMLESFGGP +AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN +QLVDWMIANTTGGARLRAGLPSDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYIGE +ATVKMDEFNPVFAEIGKMITE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D623_KLEPN +-----EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEEBCEB +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAVTLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPSAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter agglomerans TaxID=549 RepID=UPI0003B1E939 +--TLKSQFETLENKSGGRLGVTVVDTSDGSEY-SWRGNEIFPLCSTSKLMAVAAILKKNE +SDHSLLDKKIHINKSDMVNYNPITQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP +QQATHFARTIGDKAFRLDRKEPELNTAIPDDVRDTTTPSAMADTLNKLVLGTALKGEQRA +KLSEWMKGNTTGANSIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKDQAPIILTTYFTQ +KDKDAVARKDVLASAAKLVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis albispora TaxID=1804986 RepID=A0A344LM52_9PSEU +--AVEQEFTRLQTQHDARLGLYALDTGSGKSV-AFRADERFAYASTFKALAAAAVLDNTT +--PQQLDEVVHYTADDMLENSPISKQHLDTGMTLRDLCDAAIRYSDNTAGNLLLRRLGGP +AGLDAALTAIGDDVTSADRYEPDLNSAIPGDTRDTSTPRAMAGNLRQYVLGDALAEDDRT +LLTDWLRRNTTGATVIRAGVPADWIVGDKTGSGYYGGRNDIAVLWPPNRAPIVMAIMTSR +DEPRAKRADALLADAARVAVS-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00077AE8C1 +---TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQKNS +--TEKLNEVVTYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRLETELNEAIPGDNRDTSTAKAIATNLKDFTVGNALPDKKRN +ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Dyella sp. S184 TaxID=1641862 RepID=UPI00131A96BE +----AAQLATLERQRGGRLGVAILDTDNGRRI-GHRADERFLMCSTFKLLAVAAVLARVD +RGVERLDRRIVFGKEAVLAYAPVTSQRVGAPMTVAELCQAAITLSDNTAANLLLASLGGP +AAVTAYVRSLGDDVTRLDRIEPELNVGRPGDLRDTTTPSAMLADLHTLLLGEVLSATSRE +QLTTWLCATSTGTEQLRAGMPAGWRVGDKTGSGANRETNDIAIIWPQKRKPLLVTAYYAG +STADTGERHAVLAEVGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax avenae subsp. avenae TaxID=80870 RepID=A0A2R4EXF4_9BURK +--ALARAVQEVEASVGGRLGVALLDMATGRQD-AHRGDERFPLCSTFKLVLAAHVLRRVD +QGQERLDRRITYGKSDLMEYSPATERHADGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP +LGLTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSAAARA +RMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDIGLFWPPDRGAVMVSCYLTG +SPAPAEQRDAALARVGALAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000CE00184 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIIWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000FFB8A21 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIIWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000BA525C4 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIIWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Roseomonas mucosa TaxID=207340 RepID=A0A1S8D217_9PROT +-----AVFAGIERRVGGRLGVAVLDTATGQRA-GHREAERFPLTSTFKLLAAAAVLSRVD +AGQARLDQRIRYGRDKLVAYSPETEKHAGEEMTLAAICEAAVTLSDNTAGNLMLEQIGGP +AGLTAWLRSIGDTVTRLDRWETALNEAEPGDPRDTTSPAAMLASLQRVTLGEALSVGGQA +HLTGWLRANKTGDKRLRAGLPGGWQAGDKTGAGERGTNNDAGLLWPPGEAPILVAAYSTG +SMAPSTERDAALAEVAAAIVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI0012D981B6 +----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAFASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000BA523BC +----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000B4484C2 +----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000B9270AD +----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI000E433FBA +----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI000BA75BB9 +-tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-TYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAHNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALATSLQAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPEGWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF60919 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYIDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKADAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8AI20_9BACI +--TVNHPFSKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFGLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSFGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus pseudomycoides TaxID=64104 RepID=UPI000BEB8D08 +--ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS +--IDKLDEVITYTKDDLVEYSPITEKHMDTGMTLGEIAEAAIRYSDNTAGNLLFKKLDGP +KGFEKALRQIGDKVTMADRFETDLNEAIPGDIRDTSTAKTLATDLKAFAVGNVLPTDKRK +ILTDWMRGNATGDKLIRSGVPKDWEVDDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR +DKEDATYDNELIAQAAKVTIN-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. Root1203 TaxID=1736427 RepID=A0A0Q6S9J1_9RHIZ +--EIDRRIGELEKRIGGRIGVSAIDTQTNVSF-GYRETESFPMCSTFKVLAAGMVLSRVD +KGQENLERRIVYDKDKLVTYSPETEQHVGGEMSVGELCKAAITLSDNTAGNLLLESVGGP +KELTNWLRTLGDGSTRLDRWETDLNEAKKDDRRDTTTPDAMLDTLGNLALGSVLSEPSQN +TLVEWMVANTTGAARLRAGLPDSWKIGDKTGTGNNGTAADIAIAWPPGHGPVLITTYVAE +AQVPVSEINPIFAEVGRIVTE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A076VE11_ECOLX +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLDLLNFFTQ +PPSRAES---------------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=UPI000DE9EC76 +-----HKFMQLEKKFDARLGVYAIDTGTNRTV-AYRPDERFAYSSTFKALAAGLVVQQNS +--MDELDEVITYTRDDLVTYSPITEQYVDTGMTLREISDAAIRYSDNTAGNLLLQELGGP +DGFENVLRKIGDHVTEADRYETDLNSAIPGDIRDTSTARALATNLKALTVDGVLPHDKRT +LLTDWMRGNTTGDELIRAAVPKGWEVGDKTGAGGYGTRNDIAIVWPPNRDPIIIAILSSR +DTEDAAYDNELIARAAKVTLTAf +>[subseq from] GIL family class A beta-lactamase n=1 Tax=Citrobacter TaxID=544 RepID=UPI000BBD050A +-pTTLNKVKEAESVLPARVGYAELDLISGEILeSYRLQERFPMMSTFKVLLCGAVLARVD +AGKERLDRRIPFSRRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGP +QGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILTTTSQQ +QLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYITE +SQATMEARNRQIAGIGATLIQHw +>[subseq from] Beta-lactamase n=3 Tax=Rhizobium fredii TaxID=380 RepID=A0A0T6Z3T6_RHIFR +--DVTELLAELEKRTGGRLGVAVLDTETNTSF-GYRETERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGKDVLLPHSPVAEKHVGGEMTIAELCDAAITISDNAAGNLLLESFGGP +AGLTSWLRSIGDEATRLDRTEPDLNEARFGDPRDTTTPAAMIGTLGKLAFGSVLSESSRQ +QLIEWMVANTTGDARLRAGLPKSWRIGDKTGTSSTGAVSDIAFAGPESRGPILIAVYTGE +AKLRPAELNPIFAEIGRIVA--- +>[subseq from] Class A beta-lactamase n=3 Tax=Rhizobium fredii TaxID=380 RepID=A0A2A6LX54_RHIFR +--DVTELLAELEKRTGGRLGVAVLDTETNTSF-GYRETERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGKDVLLPHSPVAEKHVGGEMTIAELCDAAITISDNAAGNLLLESFGGP +AGLTSWLRSIGDEATRLDRTEPDLNEARFGDPRDTTTPAAMIGTLGKLAFGSVLSESSRQ +QLIEWMVANTTGDARLRAGLPKSWRIGDKTGTSSTGAVSDIAFAGPESRGPILIAVYTGE +AKLRPAELNPIFAEIGRIVA--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000472BBC5 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=A0A366ES13_9BACI +-----HKFMQLEKKFDARLGVYAIDTGTNRTV-AYRPDERFAYSSTFKALAAGLVVQQNS +--MDELDEVITYTRDDLVTYSPITEQYVDTGMTLREISDAAIRYSDNTAGNLLLQELGGP +DGFENVLRKIGDHVTEADRYETDLNSAIPGDIRDTSTARALATNLKALTVDGVLPHDKRT +LLTDWMRGNTTGDELIRAAVPKGWEVGDKTGAGGYGTRNDIAIVWPPNRDPIIIAILSSR +DTEDAAYDNELIARAAKVTLTAf +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. (strain Marseille) TaxID=375286 RepID=A6SVG3_JANMA +--TAQEELKRIESAARGRLGVSALNMANDNRV-EYRAEERFPLCSTFKVMVAAAILQRSA +SEAQLLQKRIRYKKDQVEKYAPVTQKHLADGMTIAELCAATLQYSDNAAANFLMTELGGP +AAVTAYMRSIGDDVFRLDRWEPELNSAIPGDERDTSTPAAVERSLEKIALGNALANPQRE +QLVSWLKGNTTGSKRMLAGVPRGWIVGDKTGTGSYGTTNDAGILWTAKGTAIVAAIYFTQ +NDKDAAAREDVIAAATRIVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000BF308D4 +------SFIKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI000568C149 +--EIDRRVGELEKRIGGRIGVSVIDTETNISF-GHRETESFPMCSTFKVLAAGLVLARVD +KGQENLERRIVYNKDKLVTYSPETEQHVGGEMSVGELCKAAITLSDNTAGNLLLESLGGP +KELTNWLRTLGDGSTRLDRWETDLNEAKKGDQRDTTTPDSMLDTLGNLALGSVLSEPSRN +TLIEWMVANTTGAARLRAGLPDSWKIGDKTGTGNNGTAADIAIAWPPGHGPVLVTTYVAE +AQVPVSEINPIFAEVGRIVTE-- +>[subseq from] Uncharacterized protein n=1 Tax=Chromobacterium sp. Panama TaxID=2161826 RepID=A0A2T5NIF4_9NEIS +----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPMCSSFKGFLAAGVLAQSQ +AKPGLLDKRIRYSKTTLPNWSPITTKNQANGMTVAELNAASVQYSDNGAANLLLEEINGP +AALTAFMRSIGDASFRLDRREPELNSAIPGDPRDTSTPKAVAESMQKLTLGKVLPEPQRQ +QLADWLKGNTTGNARIRAAVPAGWDVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH +AKKEAKHSDEVIAAAARAALEAf +>[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus siamensis TaxID=480071 RepID=UPI000987D2EF +----DEKFAQLENEFDARIGVYAIDTGTKQTV-AYHPNERFAYTSTFKVLAAAILLKQND +--IQELERVIPYTKDDLVTYSPVTEKHVDDGMTLLEISEAAIRKSDNTAGNLLLEAIGGP +DKFEQALRNIGDDVTQPERYETELNEFKPGNKRDTSTPKAMAANLKKVALSDFLSKNKRE +LLIDWMKGNATGDALIRAGAPEGWKVGDKSGAGSYGTRNDIAIVWPPNREPIVIAVMSRH +NKEDAEYDDALVAKAAEITL--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas mosselii TaxID=78327 RepID=A0A1X1P3L1_9PSED +hdPLRQAMQQLEAASGSIIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHHNE +AEPGLLARRIAYGAEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP +PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLTDGLPAGAQQ +QLQAWLKGNTTGDARIRAGLPKDWVVGDKTGSGDYGVANDVAVIWPKGLAPWILVVFSRG +TKQDAPWNSETIAAATRIVVEAw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5C2D2V6_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELEPNSTIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Uncharacterized protein n=1 Tax=Chromobacterium amazonense TaxID=1382803 RepID=A0A2S9X8A1_9NEIS +---ADQKIARLERVFGGQIGVYALDTGSGAAV-SYRADERFPLCSSFKGFLAASALAHSQ +SKPGYLDQILHYGKEELIAWSPISEKHQSSGMTVAGLCAATVQYSDNAAANVLMKQLDGP +AGLTAFMRAIGDSTFRLDRWEPELNTAIPGDARDTSTPRAVAESLQKLTLGTALAAHQRQ +QLVDWLKGNTTGNQRIRAAVPAGWSVGDKTGTCGYGTANDYAVIWPTGRAPIVMAVYTRA +SKKDIKHSDAVIADAAKAALE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A243G2D4_BACTU +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTRKDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] BETA-LACTAMASE n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI00001130B4 +-tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-TYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALATSLQAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPEGWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVLK-- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5Z9Q5_9BACT +--DFANRIRSIEQRTGARIGVTALDTGSGKGI-DYRSEERFPMCSTFKFLAAAVVLKRVD +DRQEKLDRFVSYGAKDILEYAPVTKAHLKDGMTLGALCAAAIEQSDNTAGNLLLDTIGGP +VGLTNFVRSIGDEMTRLDRKEPELNSAIPGDERDTTTPAAMCADIQRLVLDNVLSESSRH +QLEDWLRHNETGALMIRAGVPKTWTVGDKTGRCGNGATNDVAIIRPPGRAPVVFAIYSIG +STSSADDRAAIVADAARVVV--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AD3BBB +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRSNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRLETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNTTGDKLIRAGVPTDWEVGDKSGAGSYGTRNDITIVWPPNRAPIVIAILSSK +DEKEATYDNQLIAEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola pv. populi TaxID=487823 RepID=A0A2S6Z7W7_9XANT +---LRAQWAEIERSSGGRLGISLLDTGTGKRI-GQREDERFPMCSTFKFVLAAAVLQRVE +QGRLTLAQRVKIRTADMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAYTRSDRHEPEMNRFALDDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGTDTRNDIAIIWPPAGAPLLLTAYLNG +AKVGDAARDAALKAVAQAVATY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKH5_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLRGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI0004A137CA +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVDGP +AGLTAFLRQIGDNVTRLDRWETVLNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1KNM5_BACCE +hqATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDWVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRQ +VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAVLSSK +EEKEATYDNQLIAEAAEMIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Actinorugispora endophytica TaxID=1605990 RepID=A0A4R6V530_9ACTN +----EEEFERLEGEFDARLGVYAVDTGTDEAV-AFNADERFAYASTHKAFSVAAVLRQNS +--VEELDEVVTYTEDDLVDHSPVTERHVDTGMTLREIGDAAVRYSDNTAANLLFEELGGP +EGLDAALEEVGDDVTQVDRIETELNEAVPGDPRDTSTPRAMATTLREYALGDALPAGKRV +ILTDMLQGNTTGDALIRAGVPDGWEVGDKTGAGGYGTRNDIAVLWPPHGDPVVLAVMSSR +DAEDAEHDDALIAEAAEVVVD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A4U2TXD5_BACCE +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKRSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00111D1656 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEIITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMRDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea vagans TaxID=470934 RepID=UPI00109411F7 +-qTLTSQLEILESKSGGRLGLAVIDTSDGSKY-AWRGNERFPLCSTSKVMAVAAILKKNE +RDPHLLDKKIHISKSDMVNYNPVTRKHIGSYMSVAELSAAALQYSDNAAMNKLLSYLGGP +QQATHFARTIGDKDFRLDRNEPGLNTAIPGDERDTTTPSAMAESLKKVFLGTALKEEQRA +KLSDWMKGNTTGSDSIKAGLPDDWIVADKTGSGDYGSTNDIAVIWPKNHAPVILTTYFTQ +HDKDAATRKDVLASAAKLVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0012AB9D3E +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--KEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDASYNNALIAETAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=A0A377QLQ1_9BURK +--AAQTQLAALEKAAGGRLGVAAWRQGSDLRV-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLDQHVRYEKKDLVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAYARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia rohdei TaxID=29485 RepID=UPI0001A5526B +--SLDKQLAELEQQSQGLLGITVINTGNGRKI-QYRGTQRFPFCSTFKFILAAAVLNKSA +SQPKLLDKHLHYHERDLLSYAPITRKNLAHGMSVSQLCAATVQYSDNTAANLLIQELGGV +ESVNQFARSIGDQTFRLDRLEPELNSALPNDPRDTTTPSAMAASMNALVLGDALPAAQRE +QLALWLKGNTTGGETIRAGAPAEWIVGDKTGTGDYGTTNDIAVLWPTKAAPIVLVIYFTQ +REKDAKPRRDVLAAATKILLSH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A172WCE9_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQP +QLLQWMVDDRVAGPLIRSVLPAGWFTADKTGAGKRGARGIVALLGPNTKAKRIVVIYLRD +TPASMAERNQQIAGIGAALI--- +>[subseq from] Beta-lactamase n=2 Tax=Lysinibacillus xylanilyticus TaxID=582475 RepID=A0A0K9F523_9BACI +----IDKFEQLEKKYDARLGVYAIDTGTKKTV-EFREDERFAYTSTFKALAAGAVLQQNS +--IEELNKIVTYTSDDLVTYSPITEKYVDTGMTLKDISEAAIRYSDNTAGNLLFKELGGP +EGFETSLKKLGDQVTNAERIETGLNEAVPGETRDTSTPKALANDLQAYALGEVLTHEKQT +MLVDWLKRNTTGDNLIRAGVPKGWEVGDKTGGGGYGTRNDIAIVWPPNREPIVIAILSSR +DKQDATYNDELIAQASEVVMNVf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00138E6CA7 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYESDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013C94D14 +-----PRFAELETTSGARLGVFAVDTGSGRTV-AHRADERFPMASTFKGLACGALLREHP +LSTGYFDQVIHYSAAELVEYSPVTETRVETGMTVRELCDAAITVSDNTAGNQLLKLLGGP +EGFTASLRSLGDVTSRLDRWETDLNTAIPGDERDTTTPAALAADYRALVVGDVLGAPERD +QLKAWLVANTTGATRIRAGLPADWTVGDKTGSPAYGSALDVAVAWPPGRAPIVIAVLSTK +SEQDAEPDNALLAGATRVVVD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. LB(2018) TaxID=2293324 RepID=UPI000E2EE1D2 +hqATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK +VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAVLSSK +EEKEATYDNQLIAEAAEMIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. CIAT894 TaxID=2020312 RepID=A0A1W6KJG2_9RHIZ +-dNVEKRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGEEKLDRRVTYGKDKLVDYSPLSEKHADADMTITELCEAAVTVSDNTAGNLLLESFGGP +PALTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLVAWLVASTTGGERLRAGMPAEWKVGDKTGTGPNGSFGDIAVIWPPDRGPIVAAVYIAE +ATVPVKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus albus TaxID=2026189 RepID=UPI0014195243 +-qATHKEFSQLEKKFDARLGVYAFDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDNRDTSTAKAIATNLKAFTVGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus amyloliquefaciens Y2 TaxID=1126211 RepID=I2C3T3_BACAM +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMQGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B07B46 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAAAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAAYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobacter sp. SG703 TaxID=2587140 RepID=UPI0014462546 +------RWAAIEAESGGRLGVAVLDTATGQVD-GHRLDERFPMCSTFKWLAASLALQRVD +TGIERLDRRIVVRREVLLSNSPVTEKHVGGDMSIAELCEAAVLVSDNAAANLLLASFGGP +AAITRHARALGDTKTRLDRTEPALNEARPGDPRDTTTPHAMAVALRSALLGTALSDASRA +RLVQWMEAVRTGVDRLRAGVPPGWRVADKTGTGARGSTNDVAVIWPPQRAPLVVTAYLTD +SKADAARRNAALAAAAKEAV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1S9TUL5_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A1Y4X4H6_BREBE +---MDIKFAALEKQFGARLGVYAIDTETDLAV-AYRQDEQFAFASTYKALAAGAVLHQKP +--LEELNKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP +KGFESALRQIGDSVTKSERYETELNEAKPEDLRDTSTPKALATSLRAYTVGNALSSDKQK +ILIEWLQGNTTGAKLIRAGVPKDWIVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR +DKQDATYDDALIAEATKIVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus siamensis TaxID=659243 RepID=UPI000C19A6DF +---TNKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNDIIRYTKDDLVTYSPITEKHLDTGMRLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALISEAAKAALD-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-29 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A288UKE4_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000B45220C +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMQGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000D725277 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMQGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE3E9D2 +--DIEKQLAALEKRTGGRLGVYVLDTKTKVTF-AHRPDERFAMCSTFKALAAAFVLARVD +KGEEKLDRRIPISKKHLLSYSPIVEKHVGGGMTVGELCAATVTYSDNAAGNLLLASFGGP +KGLTDWLRSIGDETTRLDRIEPELNEAKIGDPRDTTSPKAMTETLGKLLLEDVLSPGSRD +QFSAWLVANTTGDRRLRAGLPKGWIIGEKTGTSGRGEAGDIGFMRPSEGNTILASVYIAE +GKKKTKELEPVFAEVGKLIA--- +>[subseq from] Beta-lactamase n=2 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=R7Z7I5_LYSSH +--TTMEKFEQLEKEYDARLGVYAIDTGTKKIV-EFREDERFAYTSTFKALAAAAVLQQNS +--IEELNKIVTYTSNDLVTYSPITEKYVDTGMTLKDISEAAIRYSDNTAGNLLFKELGGP +EGFETSLKKLGDQVTNAERIETGLNEAVPGETRDTSTPKALANDLQAYTLGDVLTHEKQT +MLVDWLKRNTTGDNLIRAGVPKGWEVGDKTGGGGYGTRNDIAIVWPPNREPIVLAILSSR +DKQDANYNDELIAQATKVVMNVf +>[subseq from] Beta-lactamase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A0D0QU86_9BACI +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKITLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A150B9E0_BACCE +----YKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPITEKHIDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMSDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALSDHKRN +ILTEWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIVAILSNK +DEKEAIYDNQLIAEAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF81ACA +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELAAASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia coubleae TaxID=356147 RepID=UPI00083120DB +-----TQYATLESKYSARLGLSVTDTGTGATV-AYRADERFPIASTFKGLACGALLKAHP +LSTGYFDQVIHYTAADLVEYSPETEKHVDTGMTVAALCHATITLSDNTAGNLVLRLLGGP +AGFTAFLRTLGDNVTRLDRWETELNTAIPGDERDTTTPAALAADYRALVLGDVLAEPERT +QLADWLKANTTGGKRIKAGLPADWTVGDKTGSPAYGSALDVAIAWPPNRPPLVLAVLSTK +SEQDAEPSNELLAEATKAAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000CD8ABDC +-------FVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHX6_KLEPN +-----EQIKISESQLAGRVGYVEMDLASGRTLaTWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1N6VH18_BACCE +----NDSFAKLEKEFDAKLGIYALDTGTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYNREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTATNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia rohdei TaxID=29485 RepID=UPI000B70AFF4 +--SLDKQLAELEQQSQGLLGITVINTGNGRKI-QYRGTQRFPFCSTFKFILAAAVLNKSA +SQPKLLDKHLHYHERDLLSYAPITRKNLAHGMSVSQLCAATVQYSDNTAANLLIQELGGV +ESVNQFARSIGDQTFRLDRLEPELNSALPNDPRDTTTPSAMANSMNALVLGDALPAAQRE +QLALWLKGNTTGGETIRAGAPAEWIVGDKTGTGDYGTTNDIAVLWPTKAAPIVLVIYFTQ +REKDAKPRRDVLAAATKILLSH- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=J8R4H6_BACCE +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPKLNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A243N7Q8_BACTV +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium deserti TaxID=1914756 RepID=A0A328AQU5_9CAUL +----APSFTMLEARSGGRLGVHAVNLVTGKRL-AHRADERFAMCSTFKALAAAAVLARVD +AGQERLDRGVPITRADMRPHAPVTETYLDRGVSLEALCKAAVEQSDNPAANLMLKTVGGP +EGLTAWLRGIGDRATRLDRWETELNSAIKGDPRDTTTPAAMTATLGKLAVGEVLKAASRE +KLVGWMIASPTGANRLRKHLPAGWRAGDKTGTGANGSTNDVAVFWPPTGGPIVVACYITE +TSAELAVREGVMAEVGRIVAQ-- +>[subseq from] CRH family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=UPI001407F418 +----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPLCSSFKGFLAAGVLAQSQ +AKPGLLDKRIRYSKTALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLEEINGP +AALTAFMRSIGDASFRLDRREPELNSAIPGDPRDTSTPKAVAESMQKLTLGKALPEPQRQ +QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDYAVIWPPKRAPIVLTVYTKH +AKKEAKHSDEVIAAAARAALEAf +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. CCGE532 TaxID=2364272 RepID=A0A387GND0_9RHIZ +--DVDKQLTDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATASAKDVEAVFAEVSKIVT--- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0011DC992D +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLPAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000A36DE8A +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B6AEG0_9BACI +hqATYKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHIDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPLHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEMIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD67A5A +-dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +KGDESLDRRITYGKDKLVTYSPETEKHAGGDMTMAEICKAAITLSDNTAGNLMLESFGGP +AALTDWLRSIGDGTTRLDRTETALNEATKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN +QLIDWMIANTTGGARLRAGLPGDWKIGDKTGTGDNGSAGDIAVIWPPKRGPIVAAVYIGE +ATVKVDEFNPVFAEIGKMITE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011A7D318 +-qATHKEFSQLEKKYDARLGVYAIDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITFMKEDLVDYSPITEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDNRDTSTAKAIATNLKSFTVGNALPVHKRY +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPDRAPIIIAILSSK +DEKDAPYDNQLIAEATEVIVN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A172WCD4_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQP +QLLQWMVDDRVAGPLIRSVLPAGWFTADKNGASKRGARGIVALLGPNNQAKRIVVIYLRN +TPANMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-920 TaxID=1463921 RepID=UPI0004C8B3A3 +--DARRRLRELEKGYPGRIGLHALNTGTGATL-GYRADERFAIASTFKVLAAAAILRRAR +EEPGLLDTVIRYGRDDLVTYSPRCEMHLATGMTVRELCDATITYSDNAAGNLLMRRIGGP +SGITRFARSLGDPHTRLDRWETDLNTNIPGDPRDTTTPAAMTANLRKLVLGDALAPLDRD +QLIRWLVENTTGDKRIRAGLPEGWRVGDKTGSPAYGGINDVAVAWPPKGAPLVISVYTTR +LDPDTPGEDRIAADMTRIAVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0008FE5329 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGALLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=2 Tax=Prauserella muralis TaxID=588067 RepID=A0A561FK76_9PSEU +--EHERALRQLERRFGARLGVVAEHTGTGRTL-RHRPAERFAMCSTFKVLAAAAVLRRSE +DERRLLRRRIGISAADLVPYSPVCERYAGSGLTVADLCEAAVSHSDNTAANKLLELVGGP +RGVTALAHAAGDTVTRLDRVEPDLNSAVPGDPRDTTTPANIAATYRALVLGDVLAAPGRE +RLRAWMLATTTSADKMRAGVPESWRVADKTGSGGYGTGNDVGIVWPPSGSPLVIAVLSTR +GERDADADPALIAEVTTIAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8R2N8_BACCE +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRLETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK +VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. LK2 TaxID=1628206 RepID=A0A0J6KWS9_9BACI +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVINYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=UPI0005372474 +--AAQTQLAALEKAAGGRLGVAAWRQGSDLRI-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLDQHVRYEKKDLVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAYARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI0011EB3E20 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAETAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000DE1CE69 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAETAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8PZ17_BACCE +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRSNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +RGYEKALRQIGDRVTMSDRLETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNTTGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPQNRAPIVIAILSSK +DEKEATYDNQLIAEAAEVVID-- +>[subseq from] Inhibitor-resistant carbapenem-hydrolyzing class A beta-lactamase KPC-44 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A4Y5JTU1_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAV------------ +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF4A610 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTDPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. BJB446 TaxID=2048009 RepID=UPI000C109AC9 +--AAQAQLAALEQAAGGRLGVAAWRQGSDLRV-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLDQHVRYEKKDLVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAYARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLIIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000F5277D1 +----NHNFAKLEEEYDVKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEELNQRITYTRGDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILKQLGGP +TGFKKALEEMGDNVTNPERFEPDLNEVHPGETHDTSTPKALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPFVLAVLSSR +DKKDADYNDKLIAEATKEVIK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0002EE964D +-qATHKEFSQLEKKFDAQLGVYAIDTGTNETI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPITEKHIDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPDDKRK +VLTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SRB_8 TaxID=1969377 RepID=A0A328L4S0_9BACI +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIITILSSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium tropici TaxID=398 RepID=A0A329YJ80_RHITR +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD +QGTEKLDRRVIYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP +AALTAWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPILVTTFVAE +ATASAKDIEAVFAEVSKIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1S9T8H5_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRSGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00066531A5 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQKI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0013D52160 +-----EQIKISEGQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLANGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BDRD-ST196 TaxID=526976 RepID=C2SKH1_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRSGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A1S9YQW4_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium currus TaxID=2051553 RepID=A0A2R4WJE4_9RHIZ +--DAAARLAQLERRDGGMLGVEVRDTATGRRF-GHRADERFPLCSTFKAVAAAAVLARAD +EGQDDLNRRITYGSDAVLSYAPVTGKHVETGMTLAELCAAAVVWSDNTAANLMLDTLGGP +AGITAFARAHGDMVTRLDRTEPTLNTAIPGDVRDTTSPAAMVGLLDNILLGRALSARSRA +RLIGWMQDSPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG +SPAEPAARDALHAEIGRLIAR-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I7ACB5_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLXNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQI----------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B1K2S8_BACCE +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRLETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK +VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVID-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKD1_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPIDERDTTMPVAMATTLRKPLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF710A2 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus sp. AG162 TaxID=2572910 RepID=A0A542SHY7_9BACL +---MDIKFAALENKFDARLGVYAIDTETDLAV-AYRQDERFAFASTYKALAAGAVLHQKP +--LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP +KGFESALRQIGDSVTTSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGDVLPSDKQT +ILIEWLQGNTTGDKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR +DKQDATYDDALIAEATKVAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF6A19E +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEDA6B2 +---LRAQWAEIERRTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGELTLAQRVKIRASDMVEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRFAPDDPRDTTTPAAMAATLRTLLLGNTLQPASRK +QLTDWMIDNRTGDSCLRAGLSRGWKIGDKTGNNGTDTRNDIAIVWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. LX32 TaxID=2170551 RepID=A0A328AKU4_9CAUL +--DATARIRKLETDLGGRIGVSAVDTGSGRRL-GYRAGERFPMCSTFKALAAAAILHRVD +TDCDALDRRILIRKSDPKGWSPVTETHVGQDMTLEALCAAAVCYSDNGAGNLLLGALGGP +AGLTGYVRSLGDKVTRLDRWELELNRVPPGDPRDTTSPAAMQATLAKVALGKALAPASRD +KLVGWLVANTTGDDRLRAGVPKAWKVGDKTGTGDGGGVNDIAVLWPPGRAPIMAAVYTVG +SAKPAAARSAAIAEIGRIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI0004D7B732 +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVKVRASDMLEHAPVTERHIGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLADWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNV +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9Q5U3_BACCE +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000650BEEE +-----EQIKISESQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTPPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. MP5059B TaxID=1766683 RepID=UPI000875A1CE +--AAQTQLAALEKAAGGRLGVAAWRQGSDLRV-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLDQHVRYEKKDLVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAYARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLIIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Thermobifida halotolerans TaxID=483545 RepID=A0A399G6J2_9ACTN +--AVDAEFARLEEEFGARLGVYAVDTGTDEVV-AYNADERFAYASTFKALAVGAVLRRNP +--VEELQEVVTYTAEDLVAHSPITEQHVDTGMTLREVCDAALRYSDNTAANLLFDELGGP +EGLEAVLREIGDDVTNVDRIETELNEAVPGDARDTSTPRAMATSLGEFALGGALPGDRQE +ILIDMMRRNTTGGTLIRAGVPQDWEVGDRTGAGGYGTRNAIAVLWPPNGGPVLLAVMSSR +DTEDAEYDDALVAETASVVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Hamiltonella defensa TaxID=138072 RepID=A0A2D3TFV0_9ENTR +hqATIDKVKESERQLNARVGYVELDLANGQILnTYRPEERFPMMSTFKVLLCGAVLSRVD +AGLEQLDRRIKYRQSDLVKYSPMTKQHLADGMTVAELCSAAITVSDNTAANLLLSTIGGP +KGLTSFLQKTGDQVTRLDRWETELNQALPGDERDTTTPKIMAQTLHNLLTGKILSVKSRQ +QLQTWMVMNKVGGPLLRSVLPANWFIADKTGAGNHGSRGIIAALGADGKPSRIVVIYLTE +TQATMDERNKQIAEIGASLIKHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0011A1A1D6 +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQENS +--IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSERFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWEVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEVAEVIVN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BAG3X2-1 TaxID=1053183 RepID=J7V3D8_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKKDAKYDDKLIADATKIVLD-- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0012B7E69F +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD +TPVSMAERNQHIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEBC5A2 +-----DSFVKLEKEFDAKLGIYALDTDTSQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVVAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Chromobacterium amazonense TaxID=1382803 RepID=UPI0008DADBAA +---ADQKIARLERVFGGQIGVYALDTGSGAAV-SYRADERFPLCSSFKGFLAASALAHSQ +SKPGFLDQILHYGKEELIAWSPISEKHQSSGMTVAGLCAATVQYSDNAAANVLMKQLDGP +AGLTAFMRAIGDSTFRLDRWEPELNTAIPGDARDTSTPRAVAESLQKLTLGTALAAHQRQ +QLVDWLKGNTTGNQRIRAAVPAGWSVGDKTGTCGYGTANDYAVIWPTGRAPIVMAVYTRA +SKKDIKHSDAVIADAAKAALE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar mexicanensis TaxID=180868 RepID=A0A242WGG5_BACTU +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IENLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLIEIGDTVTNPERFEPELNEVHPGETHDTSTPKALATSLQAFALGDVLSTEKRN +LLIDWMKRNTTGDNLIRAGVPGGWKVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A411G932_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIA---------- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2B8DIH4_BACTU +-qATHREFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D615_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLVRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A4R4B3E2_BACTU +--TVNHSFAKLEKEFEAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTRDDLVNYNPITEKYVDTGMTLKELSDASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGETHDTSTPKALATSLQAFALGDVLSTEKRD +LLKDWMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. RA13 TaxID=1502762 RepID=UPI0005634609 +--AAQAQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTMFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLVIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas dyei TaxID=743699 RepID=A0A2S7BYT2_9XANT +---LRAEWAEIERRSGGRLGIGLLDSATGKRI-GQREDERFPMCSTFKFVLAAAVLQRVD +KGELTLAQRVKIRASDMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGEP +AGLTAFLRGIGDTHTRSDRHEPEMNRYAEGEPRDTTTPAAMAATLRTLLLGNALQPASRK +QLADWMIDNRTGDTCLRAGLPHDWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAGRDAALKAVAAAVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000BEAF525 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTKDTNYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q84H48_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQQIAGIGAAL---- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia hospita TaxID=169430 RepID=UPI000B3494AC +--ALEKQLAQIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD +QGKEQLGRTIAYSKEVVVANSPVSGPRAGGDMTVAELCEAAITRSDNTAANLLLDSIGGP +AALTAFARGIGDRITRLDRNEPTLNEATEADPRDTTTPAAMLADMRALLLGGHLSAASRE +QLTAWLAGNKTGDARLRAGLPKAWRIGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG +ATATSTQRDAAIAQVGALVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Photorhabdus khanii subsp. guanajuatensis TaxID=2100166 RepID=A0A4R4JB50_9GAMM +--SLHQQLAELENRTKGRLGVTLINTANGQEI-QYRGNERFPFCSTFKLMLVAAVLHKSM +SQSELLAKHINYSESDLQSYAPIARKNLNQGMNITQLCAATLQYSDNTAANLLIKELGGL +KAVNRFAQGLDDRAFRLDRWEPDLNSAIPDDPRDTTTPAAMATSVKKIVLGETLAAPQRE +QLVVWLKGNTTGDASIRAGTPDGWVVGDKTGGGDYGTSNDVAVLWPPEGSPVVLAVYFTQ +HQKDAESRRDVLASTTRLVMEH- +>[subseq from] Beta-lactamase n=5 Tax=Bacillus TaxID=1386 RepID=A0A371UVI5_9BACI +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRN +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIALD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS075960 TaxID=2034282 RepID=A0A2B4P2W8_9BACI +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRN +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCD424 +--DVDKQLADLEQKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAAAKDVEAVFAEVSKIIVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar zhaodongensis TaxID=180896 RepID=A0A243M3Z7_BACTU +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0013C1D463 +--NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARGD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAILDTLGNVTLGSVLAEASSD +RLIAWLVASATGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI0006C546F1 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN +ILTKWRKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSNK +KEKGATDDNQLIAEAAEVIVNAf +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces xinghaiensis TaxID=1038928 RepID=A0A3M8EUT1_9ACTN +--EVSRRLRALESEHGARLGVFARNLDTGETV-VRRADERFPMCSLFKPVAAAAILRDHD +RNGDFLARRIRYGTTDLVDHSPVTGKHVAQGMTVGELCDAAIRFSDNTAANLLLRELGGP +RAVTRFCRSVGDRTTRLDRWETELNSAEPWRVEDTTSPRAIARTYTRLIVGDALPPADRE +RLTDWMLANTTSDERFRAGLPAGWALADKTGGGHYGTNNNAGVAWTPDRTPIVLAVLTTK +PAPDAAPDNELIAKTAELLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BEDBB03 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A0G8ESS1_BACCE +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1BRF5_BACCE +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Proteus mirabilis TaxID=584 RepID=Q93LJ5_PROMI +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMGDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEI-------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFCDB51 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGL +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B2LG81_BACCE +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGL +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea vagans TaxID=470934 RepID=UPI000BAC8D12 +-qTLTSQLETLESKSGGRLGLAVIDTADGSKY-AWRGNERFPLCSTSKVMAVAAILKKNE +RDPHLLDKKIHISKSDMVNYNPITRKHIDSYMSVAELSAAALQYSDNAAMNKLLSYLGGP +QQATHFARTIGDKDFRLDRNEPGLNTAIPGDERDTTTPSAMAESLKKVVLGTALKEEQRA +KLSDWMKGNTTGSDSIKAGLPDDWIVADKTGSGDYGSTNDIAVIWPKNHAPVILTTYFTQ +HDKDAATRKDVLASAAMLVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0012EAED63 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +VLTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BEBDDB0 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00094307C4 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3M824_9BURK +---WRSALQAVESTLGGRLGVAMLDTATGRAL-GWRQDERFPMASTFKLVLAGWMLERVD +RGQESLTNRVQYERSALVPYSPVTEKHTGAVMTVGELCEATVTLSDNTAANLLLARHGGP +AGFTAFAQSLGDTHTRLDRTEPTLNEAAPGDPRDTTTPFAMLHTLRKLVLGDALSPASRA +QLTQWIVDNKTGDKRLRAGVP-GWKVGDKTGTGALGSSNDIGVLWPPAGAPVLVTCYMTG +VPAAPEVRDAAIAQVARHVA--- +>[subseq from] Beta-lactamase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3KWS0_9BURK +---WRTALKAIESTLGGRLGVAMLDTGTGRAL-GWRQDERFPMASTFKLVLAGWMLARVD +EGQESLQNRVRYEHSALVPYSPATEKHAGANMTVGELCEATVTLSDNTAANLLLARHGGP +AGFTAFTRSLGDAQTRLDRTEPTLNEAIAGDPRDTTTPMAMLHTLRKLVLGDALSAASRM +QLTQWIVDNKTGDKRLRAGVP-GWKVGDKTGTGANGSSNDIGVLWPPGGAPVLVTCYMTG +VPAAPEVRDAAIAQVAREVA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A4U2XCJ7_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-TYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRSGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A402GGN1_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNA +--MDKLNEVIKFTKEDLVEYSPVTERHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0009423289 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLQYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0009AFB425 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00061E08F2 +----NHNFAKLEEEYDVKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEELNQRITYTRGDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILKQLGGP +TGFKKALEEMGDNVTNPERFEPDLNEVHPGETHDTSTPKALATSLQDFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR +DKKDADYNDKLIAEATKEVIK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q9S534_KLEOX +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMGDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF7F746 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0009E46493 +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHIDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPLHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEMIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. Leaf160 TaxID=1736280 RepID=A0A0Q5M5W3_9BURK +----QAALGAVEAGLGGRLGAAMLDTGTGRLL-SWRGDERFPMASTFKLMLAGWMLERVD +RGQESLAQRVRYERDALVPYSPVTEKHVGADITVAELCEATVTLSDNTAANLLLARHGGP +EGFTGFARSLGDAVTRLDRTEPTLNEALPGDPRDTTTPVAMLHSLRTLVLGQALSPASRA +QLTEWIVNNKTGDKRLRAGVP-GWKVGDKTGTGSNGSSNDIGVLWPAGGAPVVVTCYMTG +VPASPEVRDAAIAQVARHVA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. UMTAT18 TaxID=1565146 RepID=A0A0F5RXC1_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKVGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKELTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacter vibrioides OR37 TaxID=1292034 RepID=R0E6D7_CAUVI +--SLSLRINALEKRGGGRLGVAVLDTQDGRRF-AARGDERFLMCSTFKMLLAGLVLRRVD +QKRERLDRRVQYGPEVLVDYSPETKKHVGPGMTIANLCQAVITLSDNTAANLLLDAVDGP +VSVTRFARALGDPVTRLDRIEPALNTARPGDLRDTTSPKAMLETLRTLTVGDALTAESRA +RLVGWLVANQTGDARLRAGLPKTWKIGDKTGSDGRHTTNDIAVIWPPGRAPLLITTYLTG +AKLDDEGRDAVLADVARAVV--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus luti TaxID=2026191 RepID=UPI00124E1FFC +-qATHKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TDKLNEVITYTKDDLVDYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQIGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Alkanindiges sp. H1 TaxID=1907941 RepID=A0A1S8CWW5_9GAMM +-qQVSQFLAQLEAQSHGRLGVSAINTANQLRI-DYQANQRFPLCSTFKLVAVAAILHQSM +RDPSVLQQRIQYSMQQVNDYAPITAQHVDSGMTVSELCAACISYSDNTAANLLLHILGGP +AALTRFTRSIGDEVFRLDRWEPALNTAIPNDTRDTSTPAAMADTLQRLLVGNVLAPTQRE +LLLYWLKNNTTGNSRIRAGVPKDWVVGDKTGTGAYGTSNDVGILWPAQQQPIILAIYFTR +PEKTAKPYDEVIAAASRIISQ-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia terpenica TaxID=455432 RepID=A0A164MBV5_9NOCA +----EAEFASLETEYDARLGVYALDTGSGRIV-AHRADERFPYASTVKSLAAGAILRSLP +--PGALDERLTYSRADLVSGSPVTEKHVDDGMTLREAVDAAVRYSDNTAANLLFAKLGGP +KGLQQNLRDLGDTVTQVDRTEPDLNEATPGDPRDTSTPTAFAADLRRYVLGQALADPARA +LLTDMLRANTTGAELIRAGVPAGWVVGDKTGLASYGSRNDVAVLWPPNAAPIVLVVFTTR +PDKDASYDNALIAKAAAAAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. SG-MS1 TaxID=2023741 RepID=UPI001445C8E6 +--AIRERLARIEAASGGRLGVSIVDTTTSLHA-GLRADERFPMCSTFKLLAAGAVLTRVD +HGQEDLQRRVVFSASDLVPNSPGTRELTGDAMSIGELCEAALTLSDNTAANLLLASFGGP +AAVTAFARSLGDGITRLDRIEPALNEAIPGDPRDTTSPNAMLGNLRELVLGEHLSAASRA +QLLAWLAANQTGGSRLRAKLPEDWGVGDKTGTGERGTANDIAILWPPGRGPVLVTVYLTE +TDGDAARSNAAIANVGALVAE-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000665DA7D +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAINMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ +LLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=A0A3N2DWT7_RAOTE +heATVKQVKAAERLLEARVGYVELDIASGRLLaSYRPGERFPMMSTFKVPLCAAVLARVD +AGEEQLDRRVRYRQHDLVEYSPVTEKHLADGMTVAGLCAAAITLSDNTAANLLLASVGGP +QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLSGSVLSAASRQ +QLRNWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG +TEASMEERNLQIAEIGETLVKHw +>[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas wuyuanensis TaxID=1073196 RepID=A0A286CYI4_9GAMM +--ALPKRLRAIEKDSGGRLGVAVLDSGSGQQA-NWRGDERFAMCSTFKFLLAAAVLARVE +KGEEALERRIPILASDLVSHSPVTEKLVGGEASIAQLCEATMIVSDNAAANLLLPLVGGP +EGLTRFVRTLGDTRTRLDRTEPSLNSAIPGDPRDTTTPLAMLHSMQRLLLGDALADASRQ +QLLVWLRGNLTGDNRLRAGLPAGWQAGDKTGTANNGTSNDIAILWPPGRAPLLLTCYLTE +SPLASAARDGIHKAVAAAVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI0011D04D5C +--EIDRRIGALEKRIGGRIGVSVIDTQTNISF-GYRETETFPMFSTFKVLAAAMVLSRVD +KGEENLERRVVYDKAQLIDYSPETEKHVGGEMSVGELCKAAITLSDNTAANLLLETLGGP +KELTNWLRTLGDGSTRLDRIEPDLNEAKKDDPRDTTTPDAMLDTLGNLTLGTVLSEPSQN +TLVEWMVANTTGSERLRKGLPDGWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYINE +ATATTDEINPVFGEVATIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A9A5E5_BACCE +--TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKSDDKLIVEATQIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Pantoea sp. JKS000250 TaxID=1938795 RepID=A0A2V3SE58_9GAMM +-qTLTSQLETLENKSGGRLGLAVIDTSDDSKY-AWRGNERFPLCSTSKVMAVAAILKKNE +RDPHLLDKKIHISKSDMVNYNPVTRKHIGSYMSVAELSAAALQYSDNAAMNKLLSYLGGP +QQATHFARTIGDKDFRLDRHEPGLNTAIPGDERDTTTPSAMAESLKKVVLGTALKEEQRA +KLSDWMKGNTTGSDSIKAGLPDDWIVADKTGSGDYGSTNDIAVIWPKNHAPVILTTYFTQ +HDKDAATRKDVLASAAKLVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=C2PFA6_9BACI +--AMYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Inhibitor-resistant carbapenem-hydrolyzing class A beta-lactamase KPC-31 n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5C0DL16_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARYTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. DHOM06 TaxID=2291023 RepID=A0A3D8JVH4_9BURK +--AIESESASIENGVDGRLGVAIQDLETGLQA-GHRSGESFAMCSTFKLMLAASVLARVD +RREEDPERRIVYGADQLDEYAPITRENVGGQMTVGALCDAAVAMSDNTAANLLLETIGGP +PGFTAFMRQLGDTVTRLDRTEPSLNTAIPGDVRDTTTPAAMLGSMRKVLLGDALSAVSRA +QLLAWAVGNRTGATRLRAGVPRGWRVADKTGSGERGTTNDIGVLWPQDRAPILVTVYLTE +TRADLRAREGAIAEVARAISR-- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus alvei TaxID=44250 RepID=UPI0009D9DFB3 +-nQAHQQFVQLEKKYDARLGVYAIDTGTNQTI-TYRSNERFAYTSTFKALAAGVLLQKNE +--IEQLDKVITYTKDDLVEYSPITEKHVHTGMTLGELAEAAVRFSDNTAVNLFLKELDGP +KGFEKALRQIGDQVTHADRYETELNEATPGDIRDTSTPQALADDLKAFTVGNALPADKQN +LLMNWMRGNATGDKLIRAGVPIDWEVADKSGAGGYGTRNDIAIVWPPNRAPIIIAVLSSR +DKKDAAYHNELIAEAAKVTMK-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00035F908C +-----DELRALERRYGARLGVYAHNVRTGQTV-AHRAQERFAMCSTFKTVAAAAVLRDQA +-HCAPLDKVIHYPAADLVPYSPKTKEHVDSGMTVGDLCAAAIQYSDNTAGNLLLRQIGGP +AGLTRFFRSIGDPVSRLDRWEPDLNSARPGDLRDTTTPEAIGRSYGQLTVGRALAADDRE +RLVDWLRGNTTSAQRFRAGLPHRWVVGDKTGTGDYASANDVGVAWTTRKTPIVLAVLTSK +TSKDAPVDDALIADAARIVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Burkholderia verschuerenii TaxID=242163 RepID=A0A0L0MG07_9BURK +--AIEHQFASIESETGGRLGVAILDTASGTHY-AYRANERFPMCSTFKFLLAAAILERQD +RAEESLDRRIAFTKDDVVANSPVSGPRAGGAMTVAELCEAAITRSDNTAANLLLASIGGP +TALTAFARQIGDRTTRLDRIEPALNEAIDGDLRDTTTPSAMLTDMREILLSQRLSSSSRD +RLVAWLVANQTGGTRLRAGLPSNWRIGDKTGTGEQGTANDIAIVWPTGRAPILVAAYLTQ +AVAAPAQRDAAFRQIGALAA--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000BEE73C0 +-qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus TaxID=1386 RepID=UPI000CCBEAD0 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNA +--MDKLNEVIKFTKEDLVEYSPVTERHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8ZPJ0_BACCE +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYGDKLIAEATKIVLD-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-41 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5B7LI76_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF8B9F7 +-----DSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDAGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVYPGDVHDTSTPKALATSLQAFALGGVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2J9D765_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWAVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009D2B693 +-qATHREFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEVAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZHY4_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLADLSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPXVLVTYFTQ +PQQDAK----------------- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A0S3BXC1_BACTU +----NDSFAKLEKKFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEMYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKTLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKKNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIALD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS073361 TaxID=2033511 RepID=A0A2B2BUP8_9BACI +--HIHREFAELESKFDARLGVYAIDTGTNRTV-SYRPQERFAYASTYKVLAAGALLQHYS +--IDQLDELVTYNSEDIVSYSPVTQLHVDTGMTLREVIEAAVRYSDNTAGNLLLKKLGGP +EGFETALRQIGDNITQVDRYETDLNSAVPGDTRDTSTPKALAASLKAFAVSDLLPAEKRT +ILTDWMWGNTTGDALIRAGAPTGWEVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAVLSKR +DTQNATYDNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=unclassified Bacillus TaxID=185979 RepID=UPI00061869DC +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKVGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKELTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD142 TaxID=718224 RepID=J7X5R0_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAAAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAAYDNQLIAEATEVIVK-- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000E2CB1FC +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGCP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0012F8CCEA +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK +ILTEWMEGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium tubonense TaxID=484088 RepID=A0A2W4DMA5_9RHIZ +--NAEKQLADLEKKIGGRLGVSVLDTETNISL-GYRETERFPLCSTYKLLAAGFVLSRVD +RGAEKLDRRVTFGKDVLVTYSPVTEKHADTDMTIAELCEAAITMSDNTAGNLLLDSFGGP +PVLTAWLRTLNDTETRLDRKETEVNEAKKGDPRDTTTPDSMLDTVGGLTLGDTLSDASRE +ALAGWMVANTTGGQRLRAGLPTEWKVGDKTGTGDNGSYADVAIIWPADRGPILIAAYVTE +ATAPIADVNTVFAEVGKIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B8QW79_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKKDAKYDDKLIADATKIVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFA7E86 +--TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLDGP +SEFKKSLREIGDTVTNPKRFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPVVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1B1L601_BACTU +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2V2H3Q1_BACTU +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacter henricii TaxID=69395 RepID=UPI000550E8EF +-----RGINALEVRSGGRLGVAVLDTATGKTF-GHRADERFAMCSTFKALVAGLVLKRVD +QGLERLDRGIPYGPGVLVAHSPATEKHVGQGMTVGALCEATVTLSDNAAANLLLHTFGGP +PALTAFLRGLGDKVTRLDGYEPGLNVVRPGEIHDTTSPSAMLATLRALTLGPVLSPASRQ +QLIAWLVANQTGDKRLRAGLPAGWKVGDKTGSWGIGTTNDIAVIWPPGRPPLLITAYLSR +SPLDNDGRNAVIAEVARLVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI001428CA57 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Alcanivorax sp. TaxID=1872427 RepID=A0A2E9RJP7_9GAMM +-----STVQEIESRLNARVGIAMSDQETGRAW-RHHADQRFPLASTFKVLACGALLHKVD +AGDDRLDRMIHYGEADLVTYSPATGEHVDTGMTLGALCEAAITLSDNTAANLVLDAIDGP +AGLTRFLRGSGDNVTRLDRREPALNEATPGDPRDTTTPDAILETLRELLFGDTLTEPSRQ +QLLQWMKDDQVADAQLRAGIPDDWTIGDKTGAGGHGSRAIIAVMWPPQRGPILAAIYITE +TDATLEQRNAAIADIGRALA--- +>[subseq from] Beta-lactamase n=1 Tax=Pantoea vagans TaxID=470934 RepID=A0A2R4JD10_9GAMM +-qTLTSQLETLESKSGGRLGLAVIDTADGSKY-AWRGNERFPLCSTSKVMAVAAILKKNE +RDPHLLDKKIHISKSDMVNYNPVTRKHIDSYMSVAELSAAALQYSDNAAMNKLLSYLGGP +QQATHFARTIGDKDFRLDRNEPGLNTAIPGDERDTTTPSAMAESLKKVVLGTALKEEQRA +KLSDWMKGNTTGSDSIKAGLPDDWIVADKTGSGDYGSTNDIAVIWPKNHAPVILTTYFTQ +RDKDAATRKDVLASAAMLVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia mimosarum TaxID=312026 RepID=UPI00047F147B +--AFEKQLAAIEAQVGGRLGVAMLDTASAHVR-GRRMHERFPMCSTFKLLLASAVMARKD +HGEEDLARRVVYSPAQVVSYSPVSGSRAGGEMTVAELCEAALTRSDNTAANLLLESVGGP +SAITAFARGLGDPLTRLDRNETSLNEAIPGDPRDTTTPAAMVANLHELLLGERLSAASRE +QLIAWLVANETGDARLRAGLPKEWRVGDKTGTGDRGTANDIAIVWPTGRAPILVATYLTG +ATASSAQRDAAIAKVGACMA--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=unclassified Bacillus TaxID=185979 RepID=UPI000D327A77 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVVIN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0009BB9B5B +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVVIN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0U2SP59_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNR------------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. JFL15 TaxID=1679193 RepID=UPI0012E13B9A +---TNKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS +--NEKLNDIIRYTKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPGRAPIVLAILSNR +FTEDANYHNALISEAAKAALD-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas axonopodis pv. melhusii TaxID=487834 RepID=A0A1T1P937_9XANT +--MLRAQWAQIEHGTGGRLGICLLDSATGKRL-GQRDDERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLATYLNG +AKVDDAARDAALKAVAVAVH--- +>[subseq from] BBI family class A beta-lactamase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI0007D8A259 +---MDIKFAALEKQFGARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP +--LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP +KGFESALRQIGDGVTKSERYETELNEAKPEDLRDTSTSKALATSLRAYTVGNALSSDKQK +ILIEWLQGNTTGAKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR +DKQDATYDDALIAEATKIVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium erythrophlei TaxID=1437360 RepID=A0A1M7UV24_9BRAD +-eKLSRNFAELEKERGGRLGVAVADTQNGNSA-VYRGDERFPICSTFKTLAVAALLARVD +AGQERLDRRLRFEAKDVVVYSPVSKNRAGGEMSLAEICEAAITLSDNTAGNLLLANLGGP +EGLTAYMRSLGDTVTRLDRNEPDLNEALPGDVRDTTSPFAMLSDLRTLVIGNALTAASKE +RLVGWLVGNKTGDARLRAGFPRDWRVGDKTGSGEKGTANDIAVVWPSNRSPLFVSVYLTG +GSPEADHRNATLAAVARLVA--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001298A475 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEVTEVIVK-- +>[subseq from] class A beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0011A9B347 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKRSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF5E9B6 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELAAASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. N35-10-4 TaxID=1866315 RepID=A0A1J9TDQ7_9BACI +-qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGS +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKDLTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIAEAAEVVVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus sp. CM-4 TaxID=1354277 RepID=UPI0003887512 +-tEIKDRFQSLEDEFDATLGVYALDMGTNESI-AYRSDERFAYTSTHKVLAVGALLQQKS +--IAELDERITYTNDDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAANLIFNQIGGP +SGLKKVLRNIGDDVTDPQRIEPALNDFTPGEPADTSTPKALVNSLQAFTLGDALPKEKRL +LLMDWMKRNTTGDHLIRAGVPDDWEVADKTGAGSYGTRNDIAIIWPPEGDPIVLAILSKR +DQKDAEYDDKLIAETTKAVIDH- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0003F97F41 +--NIEHRLATLEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARTD +KGEENLDRRVNYGKGKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTNWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAILDTLGNLTLGSVLTETSSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=UPI0012E0E7F8 +--DLDETFATIESEYDARVGVYAIDTGSDQTI-DYRSEERFAFASTYKALAAALVLKQNT +--MEELEEVITYTEDDLVSYSPITEKHVDTGMTLAELSEAAVRTSDNTAGNLLFEELGGP +EQFQQSLREIGDDVTQSDRYETALNEFTPGNTRDTSTPAALATSLQGFAVGDQLTDDKRE +RLLDWMQGNATGDTLIRAGAPEGWTVADKSGAGRYGTRNDIAVVWPPDREPIILAIMTRH +DTEDAEYDDALIAEVAEATLN-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=I6ZFS9_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAXXRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIA---------- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. TER-1 TaxID=2499852 RepID=A0A437NXE9_9RHIZ +--DAADALAALERKDGGRLGVAVLDTGSGRRL-EHRAGERFPLCSTFKAVAAAAVLARAD +AGEDSLERRIAYGPGDLLDYAPVTRERVREGMSLADLCAAAVVWSDNTAANLMLATFGGP +EGLTAFIRRQGDAVTRLDRTEPTLNEAAPGDPRDTTSPTAMVGLLGRLLLGDALAPASRE +RLIGWMVASPTGAKRLRAGLPPDWVVGDKTGTGENGTANVVALVRRPNAAPLLAAVYLTG +SPATPDARNALHAEVGRLVAATf +>[subseq from] Beta-lactamase n=1 Tax=Thalassospira lucentensis TaxID=168935 RepID=A0A154L2A3_9PROT +-dRLTDAIHAVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAILHKVD +LGTETLDRRIIYGVEDLVTYSPTTEKHVDSGMTIGELCEATLHLSDNTAANLILDALGGP +DELTAYLRDIDDDVTRLDRIEPDLNTAKPGDPRDTTTPDAMRASLAYLLLGDALSADSRQ +LLEDWLTGNQVSGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPEQKPVIVAIYITQ +TSASMDERNAAIADLGQEIA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A8HNT0_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTNFTQ +P---------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. NBRC 111133 TaxID=1661048 RepID=UPI000761399F +--SLQHEFSALERSLDVTLGLWAHDTGTGKTL-SYRAEERFAFCSTFKVVLAAAILAKSS +ADKGLLERKISYSEDDLVTYSPVTERHLANGMTVSELCAATLQYSDNTAGNLLLEQIGGP +AGLTDFARHVGDASFRLDRTEPELNTALPDDPRDTTTPLAMGVTLQKLLLGNSLPEGARR +QLQEWLKGNTTGDKRIRAGVPQGWAVGDKTGSGDYGVANDVAVIWPSGKAPWVVTIFTRG +QRKESPWNNEIISS--------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1X6Q8Q5_BACMY +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1ZT22_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVINYTKDDLVEYSPVTEKHVDTGMTLGEIVEAAVRSSDNTAGNILLNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNKAPIIIAILSSK +DEKEDTYDNQLIAEAAKVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D625_KLEPN +-----EQIKISEGQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0004974B7D +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus fortis TaxID=2126352 RepID=A0A2P7UMZ3_9BACL +--AMDQKFAALENKFDVRLGVYAIDTDTNLAV-AYREDERFAFASTYKALAAGAVLHQKS +--LEELDKVISYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP +KGFESALRQIGDDVTTSERYETELNEAKPEDIRDTSSPKALATTLRAYTVGDVLSSDKQT +IITEWLQGNTTGDKLIRAGVPKDWKVGDKTGAASYGTRNDMGIIWPPNKKPIVIAVLSSR +DKQDATYDDALIAEATKVAVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF5B019 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD52FC1 +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTVAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGSNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAAAKDVEAVFAEVGKIIVD-- +>[subseq from] Beta-lactamase n=7 Tax=Bacillus cereus group TaxID=86661 RepID=R8K5S2_BACCE +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2B4XIS2_BACMY +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8R6_9BACT +-----------EDQLGARVGYTELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. UNC41MFS5 TaxID=1449046 RepID=UPI000479B864 +--QIHREFAELENKYDARLGVYAIDTGTHRTV-SYRPKERFAYASTYKALAAGALLQHYS +--IEQLDQLVTYKSEDIVSYSPVTQLHVDTGMTLREVIEAAVRYSDNTAGNLLLEKLGGP +EGFETALRQIGDNVTQVDRYEPDLNSAVPGDTRDTSTPKALATSLKAFAVSDLLPNEKRK +ILTDWMWGNSTGDALIRAGAPTGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR +DAQNATYDNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001145EF16 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQIGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD666F4 +-eDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +RGDETLDRRITYGREKLVTYSPETEKHAGGEMTLAEICKAGITLSDNTAGNLMLESFGGP +AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSVLAEDSAN +RLVDWMVANTTGAARLRAGLPRDWRIGDKTGTGDNGAAGDIAIIWPPGRGPIVAAVYMAE +TTVKMDEFNPVFAEIGRMIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. THG-D6.12 TaxID=2484251 RepID=UPI00130331EB +--AINQKFVHLEKKFDARLGVYAIDTGTKRTI-AYRSDERFAYASTYKVLAAGVVLQQNS +--IDRLDEVIHYSKDDLVSYSPITEQHVDTGMTLKEICDAAIRYSDNTAGNLLLEKLGGP +KGFEKSLREIGDTITRSDRFETELNEATPGDLRDTSTPKALAKSLKAFTVNNVLPSDKRR +ILTDWMRGNTTGDKLIRAGAPKGWAVGDKSGAGSYGTRNDIAIVWPPHKKPIIIAILSSH +KTKDATYNDELIENAAKVALNAf +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AC9819 +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus sp. Marseille-P3787 TaxID=2079532 RepID=UPI000D0E6D83 +--AIESSFVQLEEEYGAKLGVFAIDTGTGRSI-AYRPDERFAYASTYKALAAGLILMNSS +--ADELDQVITYTKDDLVSYSPVTEKHVKTGMTIRDICEAAVRYSDNTAGNVLLKKLGGP +EGYEKALKQIGDQVTQADRYEPELNEAVPGDTRDTSTPRSLATTLSSFIVGNVLTDDKRS +ILIDWMSGNATGDELIRAGAPKDWKVADKSGAGNFGTRNDIAIVWPPNGSPIIVAIMSNR +DVQDADYDNALIAQAAKVALD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A2A7Z2E8_BACMY +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKKDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Virgibacillus massiliensis TaxID=1462526 RepID=A0A024Q8U8_9BACI +--EIKDRFQSLEDEFDATLGVYALDMGTNESI-AYRSDERFAYTSTHKVLAVGALLQQKS +--IAELDERITYTNDDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAANLIFNQIGGP +SGLKKVLRNIGDDVTDPQRIEPALNDFTPGEPADTSTPKALVNSLQAFTLGDALPKEKRL +LLMDWMKRNTTGDHLIRAGVPDDWEVADKTGAGSYGTRNDIAIIWPPEGDPIVLAILSKR +DQKDAEYDDKLIAETTKAVIDH- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B3U3T8_BACCE +--ATYKEFSQLEKKFDAQLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRFSDNTAGNILFNKLGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNKAPIIIAILSSK +DEKEDTYDNQLIAEAAKVVIN-- +>[subseq from] Beta-lactamase n=2 Tax=[Polyangium] brachysporum TaxID=413882 RepID=A0A0G3BG19_9BURK +---FEAQCKALEAEVGGRLGVALLSTSTGVSA-GYRADERFPMCSTFKWLAAAYLLSRVD +AGMERLDRRIGYGSNVLIDHSPVTSQHVAGGMTLAQLCEATITVSDNAAANLILDTFGGP +AALTRYLRSLGDNVTRLDRTEPALNHVPPGDERDTTTPAAMTSDLRRLLLGTALSTASRD +QLTRWMLATQTSGTRLRANLPPRWQLADKTGTAN-GTANDVGVFWSPAGEAIALSVYLTE +CRAPAAQQNAAIAEVARWVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI00113FA9D1 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMQGNATGDELIRAGAPSGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinospica acidiphila TaxID=304899 RepID=UPI0013D726F3 +------SLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP +--GARLDERITYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAANLLLRDIGGP +RGVTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVLGDALPAAGRA +LLTDWLVRNKTGDRRIRAGAPRGWRVGDKTGSGDWGRCNDVAVLWPGGGPPLMLSVLTER +PDRAASPSDELVAEAARRVL--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium hainanense TaxID=52131 RepID=A0A1C3UFT2_9RHIZ +--DVDKQLADLEKRTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAAGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCNAAVTLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE +ATAPAKDVEAVFAEVGNIVV--- +>[subseq from] inhibitor-resistant carbapenem-hydrolyzing class A beta-lactamase KPC-33 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C32FA0F +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARYTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus licheniformis TaxID=1402 RepID=A0A1Q9FXS5_BACLI +----NHNFAKLEEEYDVKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEELNQRIAYTREDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILKQLGGP +TGFKKALEEMGDDVTNPERFEPDLNEVHPSETHDTSTPKALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR +DKKDADYNDKLIAEATKEVIK-- +>[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI0007791762 +---MKDDFAKLEEQFDAKLGIFALDTGTNRTV-TYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALATSLQAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPEGWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVVK-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas graminis TaxID=158627 RepID=A0A1I0IJV2_9PSED +--AIQQQLADLESRHGGRLGVAILDTASQRLI-SHRGDERFALCSTFKCLAAAHVLARVD +RKQEDLSRRIVYSAEQLVAYSPTTELHVGGQLSVGSLCEAAMTLSDNTAANLLLDSMGGP +EGLTAWLRLIGDTRTRLDRREPDLNENRPQDLRDTTTPVAMLHTLNTLVLGDELTLPSRD +QLTAWLVNNQTGDKKLRAGVSGGWRVGDKTGSGSNNATNDVAVIWPGDRPPILVTAYYTG +SKASADQINAVMADIGRLA---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=J9AUM8_9BACI +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHIDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPLHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEMIVK-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2B5LXC0_9BACI +----NDSFAKLEKEFDAKLGIYALDTGTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYNREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPQLNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKENAKYDDKLIAEATKIALD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A7X087_9BACI +--ATNREFTQLEKKFDARLGVYAIDTGTNQTI-TYRPNERFAYASTYKALAAGTVLHINS +--MDKLNKVIHYTKDDLVEYSPITEKHVDTGMTLGEIAEAAVRYSDNTAGNLLFKTLNGP +QGFEKALRQMGDKVTCANRFEPELNEAIPGDIRDTSTPKALATDLKDFTVGNALPAEKRK +ILTDWMRGNATGDKLIRAGVPKDWKVGDKSGAGDYGTRNDIAVVWPPNRAPLIIAILSSR +DKKDATYDNELIVQATKVIMN-- +>[subseq from] class A beta-lactamase n=1 Tax=Grimontella sp. AG753 TaxID=2183905 RepID=UPI000D761D1F +-----ETVKKAEDQLNARVGYAELSLANGQMLgSYRPQERFPMMSTFKVLLCGAVLSRVD +AGQEQLARRIQYRKQDLVAYSPVTEKHLTDGMTLAELCSAAITMSDNTAGNLLLSAIGGP +SELTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQMLRQLLNGKILTPASQQ +QLMAWMEADKVGGPLIRSVMPAGWFIADKTGAGERGSPGIVAALGPDGKPARIVVIYITE +TQATMDDRNKKIADIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus alvei TaxID=44250 RepID=UPI0013D9215E +-nQAHQQFVQLEKKYDARLGVYAIDTGTNQTI-TYRSNERFAYTSTFKALAAGVLLQKNE +--IEQLDKVITYTKDDLVEYSPITEKHVHTGMTLGELAEAAVRFSDNTAVNLFLKELDGP +KGFEKALRQIGDQVTHADRYETELNEATPGDIRDTSTPQALADDLKAFTVGNALPADKQN +LLMNWMRGNATGDKLIRAGVPIDWEVADKSGAGGYGTRNDIAIVWPPNRAPIIIAVLSSR +DKKDAAYHNELIAEAAKVTMK-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007C84394 +--SAQPQFVELERALNGRLGVFALNTADGARL-GYRAEERFPVCSTFKVLVAAGILERST +QIAGLMQQRINYLPSDLVTHSPVTEKHLVTGMTVAELCDAVMRYSDNTATNLLMKILGGP +AGVTDFARSIGDREFRLDRWEANLGTAIPGDPRDTSTPEAMGRSLQRLVLEDALGVRQRK +QLQVWLRSNTTGANCIRAGVPSDWQVGDKTGAGAYGTRNDVAVLWPPHRPPVILTVYSTQ +HEKDAKWREDIIASAARIVV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1QP29_BACCE +---TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKAIAAGVLLQKNS +--TEKLNEVITYTKEDLVDYSPVTEKHVGTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTLSDRFETELNEAIPGDNRDTSTAKAIATNLKNFTIGNALPDHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVN-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. KBW07 TaxID=2153358 RepID=A0A3N7CAY0_9BURK +--SAEAQLAALETASGGRLGVVAFNSTSGARV-QHRAHERFPFCSTFKLMLAAAILERSA +KDASLLTRHVNYSKGDIISYSPITEKNLATGMTVAALCAATVQYSDNAAANLLMKILGGP +PAVTAFARSIGDQAFRLDRWETELNTAIPGDLRDTTTPAAMADSVHRLALGDALGTAQRD +QLQAWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGTTNDVGVLWPPAGAPLVVAVYLTF +PDKDAKGRNDVIASAVRIVV--- +>[subseq from] Beta-lactamase n=1 Tax=Desulfarculus baarsii (strain ATCC 33931 / DSM 2075 / VKM B-1802 / 2st14) TaxID=644282 RepID=E1QJV5_DESB2 +--AAATRLAAIETSLDGRLGLFALNTADGRTL-AHRSDERFAMCSTFKLVLAGAILAQSA +QTPGLLERRVAYGPEALVSYSPITQKHAAGGMTVAALCAAAVRHSDNTAANLLLDQLDGP +AALTTFARTIGDNHFRLDRREPELNTAIPGDPRDTTTPAAMGRSLQRLALGRALPAEGRA +LLCAWLRGCVTGAARIRAGVPAGWVVGDKTGTGAYGVANDVAVLWPAAGPPVLLAIYTAR +RQKDAAPRNDVIVAAAKVVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas sp. Leaf131 TaxID=1736270 RepID=A0A0Q5GHU7_9XANT +---LRAQWAEIERGTGGRLGISLLDSATGWRL-GQRENERFPMCSTFKFVLAAAVLQQVD +RGKLSLAQPVKIRASDMLSHAPVTERHVGGTLSVGELCRATMIYSDNPAANLLFPLVGGP +PGVTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTRGWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI0011560A1A +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. YK2 TaxID=1860096 RepID=A0A1E4Y0Q5_9RHIZ +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTVAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRE +QLVNWLVANTTGSNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAAAKDVEAVFAEVGKIIVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Roseomonas deserti TaxID=1817963 RepID=UPI001331BC45 +----PRRFAQIEAARGGRLGVAVLDTGTGRQA-GYRQDERFPILSTYKTLAAAAVLARAD +AGMDSMERRVRFTRDDLVTYSPVTEKHVGQGMTLAALCEAAIVTSDNTAGNLLFDAVEGP +AGLTAWLRTIGDPVTRLDRLETALNEALPGDPRDTTTPAAMVLDLQALALGSVLSSSSRE +RLVAWLRGCRTGDARLRARLPQGWTAGEKTGTGERNSSNDAGLLWPPNGPPVLVAAYLTG +GAADGAVRDAALADIGAAVAE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI00080F686C +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGIRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKAIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKC1_9BACT +-----VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNGLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGLDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Methylosinus sporium TaxID=428 RepID=A0A2U1SNZ8_METSR +--ELSARVEAIERRAGGRLGVAVLS-GDGRRF-AHRADERFPMCSTFKALAVAAVLKRID +AGALSLERKIAYGQADLLDYAPATRAHVADGMSLRDLCAAAMQLSDNTAANLILGALGGP +QAVTETARSLGDEATRLDRDEPTLNSAIPGDPRDTTTPMAMARDLRELIMGRALSETSRL +LLEDWMIGNKTGAKRLRAGLPPDWGVGDKTGSGENGAANTIAIFRPPRRAPLFVAVYLAE +AGGSKEERDAVHHDVAKSIAETf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A8DZJ2_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADRTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIG------- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas pisi TaxID=56457 RepID=A0A2S7CZG5_9XANT +---LRTQWAEIERGTGGRLGISLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGTLTLAQRVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP +AGLTAFLRSIGDAQTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDACLRAGLTRDWKIGDKTGSNGTDTRNDIAILWPPKGLPLLLATYLNG +AKVDEAARDAALKAVAQAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI00077A362C +----DDSFAKLEKEYDAKLGIYALDTGTNQTV-SYRSDDRFAFASTSKSLAAGALLRQNS +--IEALNERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDATYDDKLIADATKIVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD146 TaxID=1053236 RepID=R8N2P9_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGDWEVADKTGSGSYGTRNDIAIIWPPNKKPLILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] BETA-LACTAMASE TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000181CFD6 +--------------RPCRVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGRRGSRGIIAALGPDGKPSRIVVIYTTG +SRKKTDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0004BAFBA2 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNEIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +TLTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BED8499 +----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DQEDAEYDDKLIADATKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. A4 TaxID=1225184 RepID=UPI00068758BF +-eKIQQQLRQLETQSGGRLGVVLIDSADNSQI-RYRANERFPMCSTSKVMAVAALLQQSE +KNSAVLQQRLAINASDLVNYNPITEKQVGSSMTLAELSAATLQYSDNAAMNLILDHLGGP +GKVTAFAQKTGDRDFRLDRREPELNSAIPGDPRDTTTPLSMAQSLQKLTLCKALAAPQRE +QLVQWMKGNTTGSQSIAAGLPSGWQVGDKTGSCDYGGTNDIAVIWREKGAPLILTTFFVQ +PQPDAKSRRDVLAAAAKIVTAQy +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter agglomerans TaxID=549 RepID=UPI0007E5A1C4 +-qTLKSQFETLENKSGGRLGVTVIDTSDGSTY-SWRGNERFPLCSTSKVMAVAAILKKNE +SDPGLLDKKIHINKSDMVNYNPITQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP +QQATRFARTTGDKAFRLDRKEPELNTAIPGDARDTTTPSAIADTLNNLVLGTALKEEQRI +KLSEWMKGNTTGVNSIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPIILTTYFTQ +HAKDATARKDVLASAAKLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI000F60361E +----NQKFVQLEKKFDARLGVYAIETGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS +--NEKLNDIIRYTKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=C3H194_BACTU +-qATHKEFSQLEKKFDARLGVYVIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI00143694B5 +---TNKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAVPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. T12 TaxID=477697 RepID=A0A560WEQ6_9ACTN +------NLTALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAALLDRRP +--GARLDERITYGEADLVPYSPVTEKHTGKGMTVRELCDVAVRYSDNTAANLMLRDLGGP +RALTAYLRGLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVLGDALPGAGRA +QLTDWLVRNTTGDRRIRAGAPRGWTVGDKTGSGEWGRANDAAVLWPGNGSPLVLSVLTER +PDRDAAASDVLVAEAARRVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF9F9AC +----HDSFAKLEKKYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYNDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. MYb209 TaxID=1848605 RepID=A0A2S8UH07_9BACI +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI00111FF7D7 +-qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDIGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEATPGDIRDTSTAKAIATNLKAFTVGNALPDHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5RE76_9BACT +--EFENRVATIEARTGGRIGVAALDTASSKHL-DCRSEERFPMCSTFKFLAAAAVLKRVD +EKQEKLDRFVPYDAKDILEYAPVTKIHLKEGMTLGALCAAAIEQSDNTAGNLLLDAIGGP +VGLTNFARAIGDKVTRLDRKEPELNTAGPGDERDTTTPAAMLADMLQLLLGNTLSPSSRH +QLEQWLQANETGASMIRAGVPTSWIIGDKTGRGANGATNDIAIMRPPGRAPILLVIYSAG +STATANDRAAVLAEAAKIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Fictibacillus phosphorivorans TaxID=1221500 RepID=A0A168W1T2_9BACI +---TAKKFMQLEKKFDARLGLYAIDTHTNRTV-TYRPDERFAYTSTFKALASGLILQQKS +--IDELNEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLKELGGP +NGFEKALREMGDNVTKADRYETDLNSAIPGDIRDTSTARALATNLKSFTVDDELPNDKRE +ILTDWLQRNTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPNREPIIIAILSSR +DTQNATYENELIAEAAKVALDAf +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2A7BWY2_9BACI +----NNSFAKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGNALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Bacillus TaxID=185979 RepID=UPI00124DE10A +--TVNHPFSKLEKEFDSKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALTTSLQAFGLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDANYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI0012D9E646 +-----QKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0002458CD5 +-----QKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF3F332 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALVVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas axonopodis pv. commiphoreae TaxID=1101443 RepID=A0A3G2W3N9_9XANT +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP +AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia steynii TaxID=1245441 RepID=UPI00088523A0 +--ALEKQLAQIEGQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD +QGKEQLERKIVYSKDVVVANSPVSGPRAGSDMTVAELCEAAITRSDNTAANLLLDSIGGP +AALTAFARGIGDRITRLDRNEPTLNEALEADPRDTTTPAAMLADMRALLLGEHLSAASRE +QLTAWLAANKTGDARLRAGLPKAWRIGDKTGTGERGTSNDIAVIWPEGRAPILVAAYLTG +ATATSTQRDAAIAQVGVLVA--- +>[subseq from] Beta-lactamase TEM,Beta-lactamase PSE-4 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00067E6531 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPLTSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. CNB394 TaxID=1169151 RepID=UPI0003AB48E6 +-----QAFRLLEEKFDARLGVYAIDTGTGRTV-AYRPDERFAYASTYKALAAAEILDETT +--DAELDRVVRYSADDLVTYSPITEQHVATGMTLRAITDAAVRYSDNTAANLMLRHLGGP +QRFERELRGIGDKVTDPERYETELNEARPGDRRDTSTPRALAGSLRAYTVGDALEPPDRA +TLNDWLRRNTTGGALIRAGVPDGWVVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEKDADYDDALIAEATRVVTAGw +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia hospita TaxID=169430 RepID=UPI000DEEAF6F +--ALEKQLARIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD +QGKEQLGRTIVYSKEAVVANSPVSGPRAGDDMTVAELCEAAITRSDNTAANLLLDSIGGP +AALTAFARGIGDRITRLDRNEPTLNEATEADPRDTTTPAAMLADMRALLLGGHLSAASRE +QLTAWLAGNKTGDARLRAGLPKAWRIGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG +ATATSTQRDAAIAQVGALVAN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A6B8YMQ4_BACCE +----HDSFAKLEKKYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYNDKLIADATKVVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Yersinia intermedia TaxID=631 RepID=Q1W758_YERIN +--SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKDANPVPDVL----------- +>[subseq from] Beta-lactamase class A n=1 Tax=Paraburkholderia hospita TaxID=169430 RepID=A0A1H6PA63_9BURK +--ALEKQLARIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD +QGKEQLGRTIVYSKEAVVANSPVSGPRAGDDMTVAELCEAAITRSDNTAANLLLDSIGGP +AALTAFARGIGDRITRLDRNEPTLNEATEADPRDTTTPAAMLADMRALLLGGHLSAASRE +QLTAWLAGNKTGDARLRAGLPKAWRIGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG +ATATSTQRDAAIAQVGALVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. SRB_28 TaxID=1969378 RepID=UPI000DC30EC5 +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKTLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillus alvei (strain ATCC 6344 / DSM 29 / NBRC 3343 / NCIMB 9371 / NCTC 6352) TaxID=1206781 RepID=K4Z7G8_PAEA2 +-nQAHQQFVQLEKKYDARLGVYAIDTGTNQTI-TYRSNERFAYTSTFKALAAGVLLQKNE +--IEQLDKVITYTKDDLVEYSPITEKHVHTGMTLGELAEAAVRFSDNTAVNLFLKELDGP +KGFEKALRQIGDQVTHADRYETELNEATPGDIRDTSTPQALADDLKAFTVGNALPADKQN +LLMNWMRGNATGDKLIRAGVPIDWEVADKSGAGGYGTRNDIAIVWPPNRAPIIIAVLSSR +DKKDAAYHNELIAEAAKVTMK-- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0009B99C46 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMLSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVVLLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0008727FD5 +-----EQIKXSESQLXGRVGMIEMDLASGRTLxAWRAXERFPXMSTFKVXLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar toumanoffi TaxID=180862 RepID=A0A243E3C2_BACTU +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVNDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF60933 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFPYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPEDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=6 Tax=Bacillus TaxID=1386 RepID=A0A2B1TQ48_BACTU +----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYNDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. T33-2 TaxID=2054168 RepID=A0A2N5H4G2_9BACI +--QIVREFAKLERKFDARLGVYAIDTGTHRTV-AYRPDERFAYASTYKALAAGALLKHYS +--IDQLDELVTYKREDIVSYSPVTELHVDTGMTLREVSEAAVRYSDNTAGNLLLKKLGGP +EGFETMLRQIGDNVTQVDRYETDLNEAVPGDTRDTSTPRAIANSLRAFAITDLLPAEKRT +ILTAWMRGNATGDALIRAGAPKGWVVDDKSGAGSYGTRNDIAIVWPPNRSPIVIAVLSSR +DTQNATYDNALIAEAAKAAL--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZHZ7_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFSLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PQQDAK----------------- +>[subseq from] Beta-lactamase n=5 Tax=Bacillus TaxID=1386 RepID=A0A0G8EMV7_BACCE +-qATHKEFSQLEKKFNARLGVYVIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI00143DD343 +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTPPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=9 Tax=Bacillus TaxID=1386 RepID=A0A1H6U3I4_BACTU +----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYNDKLIADATKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. OK665 TaxID=1500305 RepID=UPI00056D89B7 +--DIEKQLAALEKRTGGRLGVYVLDTKTKVTF-AHRPDERFAMCSTFKALAAAFVLARVD +RGEEKLDRRIPISKKHLLSYSPIVEKHVGGGMTVGELCAATVTYSDNAAGNLLLASFGGP +KGLTDWLRSTGDETTRLDRIEPELNEAKIGDPRDTTSPKAMTETLGKLLLEDVLSPASRD +QFSAWLVANTTGDRRLRAGLPKDWIIGEKTGTSGRGEAGDIGFMHPTEGHTILASVYIAE +GKKPTKELEPVFAEVGKLIA--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=R8N2F7_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000E35979D +-qAMHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ZS0098 TaxID=1904044 RepID=A0A421P574_9ACTN +------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP +--GARLDERITYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAANLLLRDIGGP +RGVTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALILGDALPAAGRA +LLTDWLVRNRTGDRRIRAGAPRGWRVGDKTGSGDWGRCNDVAVLWPGGGPPLMLSVLTER +PDRAASPSDELVAEAARRVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE239FD +--EIDRRIGALEKAIGGRIGVSAIDTQTNISF-GYRETESFPMCSTFKVLAAGFVLARVD +KGEENLERRVVYDKDKLVTHSPETEKHVGGEMSVGELCQAAITQSDNTAGNLLLESFGGP +KELTNWLRTLGDGSTRLDRWETDLNEAKKGDQRDTTTPDAMLDTLGNLTLGSVLSEPSQS +KLVEWMVANTTGGTRLRTGLPDTWKIGDKTGTGNNGTAADIAVAWPPGHGPILMTVYVAD +ATAEISEINAIFGEVGRIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia fungorum TaxID=134537 RepID=A0A2N8Q9F8_9BURK +-eAIRQRLAQIEAESGGRLGVSILDTTSGLHT-GLRTDERFPMCSTFKLLTAGFVLMRVD +HGQETLERRVVFSKGDLERYSPATSRHTRELMSVADLCKAAITLSDNTAANLLLASFGGP +AALTAFARSIGDGVTRLDRNEPTLNEATPGDPRDTTTPNAMLGDLRELLLGERLSAPSRA +QLLAWLAANQTSGERIRAKLPKDWGVGDKTGSGDHGTANDVAILWPPGRGPILVTVYLTE +TSGDAARCNAAIADVGEVVVA-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000872E4C8 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Alcanivorax sp. TaxID=1872427 RepID=A0A2E5TE13_9GAMM +-----STVQEIESRLNARVGIAVSDQETGRAW-RYHADQRFPLASTFKVLACGALLHKVD +AGDDRLDRMIDYGEADLVTYSPATGEHVDTGMTLGALCEAAITLSDNTAANLVLDAIDGP +AGLTRFLRGSGDNVTRLDRREPALNEATPGDPRDTTTPDAILETLRELLFGDTLTEPSRR +QLLQWMKGDQVADALLRAGIPDDWTIGDKTGAGGHGSRAIIAVMWPPQRGPILAAIYITE +TDATLEQRNAAIADIGRALA--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=G9Q704_9BACI +----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Pantoea vagans (strain C9-1) TaxID=712898 RepID=D6YR32_PANVC +-qTLTSQLETLESNSGGRLGLAVIDTADGSKY-AWRGNERFPLCSTSKVMAVAAILKKNE +RDPHLLDKKIHISKSDMVNYNPVTRKHIGSYMSVAELSAAALQYSDNAAMNKLLSYLGGP +QQATHFARTIGDKDFRLDRHEPGLNTAIPGDERDTTTPSAMAESLKKVVLGTALKEEQRA +KLSDWMKGNTTGSDSIKAGLPDDWIVADKTGSGDYGSTNDIAVIWPKNHAPVILTTYFTQ +HDKDAATRKDVLASAAMLVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. K24 TaxID=1472716 RepID=UPI0004AB0FB4 +-eAIRQRLAQIEAESGGRLGVSILDTTSGLHT-GLRTDERFPMCSTFKLLTAGFVLMRVD +HGQETLERRVVFSKGDLERYSPATSRHTRELMSAADLCKAAITLSDNTAANLLLASFGGP +AALTAFARSIGDGVTRLDRNEPTLNEATPGDPRDTTTPNAMLGDLRELLLGERLSAPSRA +QLLAWLAANQTGGERIRAKLPKDWGVGDKTGSGDHGTANDVAILWPPGRGPILVTVYLTE +TSGDAARCNAAIADVGEVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B5A4F39 +-----DSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDAGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVYPGDVHDTSTPKALATSLQAFALGGILSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0009C0C6A2 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora halophytica TaxID=47864 RepID=A0A1C5HVZ3_9ACTN +-----AEFAALEQRYDARLGVYALDTGSGRTL-AYRADERFAYASTFKALAAGALLAATS +--DAELDRVVRYGREDLVMHSPVTEKHVADGMTLREAADAAVRYSDNTAANLVLAELGGP +AGFERALRGIGDTVTDPARTEPALNEAAPGDVRDTSTPRAMADSLQAYAIGGALSVEDQR +VLLDWLKRNTTGANLIRAGVPAGWQVGDKTGAGGYGTRNDIAVLWPPDAAPIVLAVMSRR +DTKDARHDDALIAEATRVTLK-- +>[subseq from] Beta-lactamase n=1 Tax=Lysobacter enzymogenes TaxID=69 RepID=A0A0S2DMN2_LYSEN +-eALRAKLAELEKRSGGRLGVSALDTGDGRRF-DLRGDERFAMCSTFKFLLSAAVLHKVD +RGDLDLRQRIAVPKSALLPHAPFTAPIAEAGASVAQLCEATMTLSDNPAANLLLPLVGNP +AGLTRFLRGIGDAVTRLDRNEPELNTAIPGDPRDTTSPNAMLASMRTLLLGDALGAASRK +QLTDWLIANKTGDKRLRAGLPKDWRIGDKTGSGN-GTTNDIAIVWPTGRKPVFVVTYLTQ +ARGEDEQRSAILADCARALAAHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A346QRV7_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIATLGPDGKPSRIVVIYTTG +SQATMDERNR------------- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5LR19_9BACT +--DFTNRILSIEQRTGARIGVAALDTGNGKRL-DYRSEERFPMCSTFKFLAAAAVLKRVD +NGQEKLHRFVFYGANDILEYAPVTKAHLKDGMTLGALCAAAIEQSDNTAGNLLLDTIGGP +VGLTNFARSVSDETTRLDRKEPELNSAIPGDERDTTTPAAMCADMQRFLLGNVLSESSQN +QLQDWLRQNETGSLMIRASVPKTWTVGDKTGGCGNGATNDVAIIRPPGRAPILVAIYSIG +STSSADDRAAIVAEPARAVVE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00136E7BD1 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDQVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=A0A2B4BB70_BACTU +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF4404A +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=2 Tax=Pseudomonas TaxID=286 RepID=A0A423GKV5_9PSED +--ELYKKLAELEDSAKGRLGVALINTANGHEI-QYRGGERFPFCSTFKLMLAAAVLHKSM +AEPGLLEKHIAYAEADLLSYAPIAKQNLKQGMSVAQLCAAALQYSDNTAANLLIKELGGV +AAVNLFVKGLGDPAFRLDRQEPELNTAIPDDPRDTTTPAAMAASVQKVVLGGALATPQRE +QLATWLKGNTTGDASIRAGTPAGWIVGDKTGSGDYGTTNDAAVLWPQTGAPVVLAVYFTQ +HQKDAEARRDVLATATRLVMAH- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. K2I17 TaxID=2014743 RepID=A0A246PJC3_9BACI +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-SYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=6 Tax=Bacillus TaxID=1386 RepID=A0A2B9U885_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNEIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000A80BE43 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNP +--IEKLNNVIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR +FTKDANYDNALIAEAAKVALD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=J8LLS3_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYNNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora olivasterospora TaxID=1880 RepID=A0A562IF15_MICOL +--------GRLEARFGARLGVYAVDTGSGRTV-AYRPDERFAYASTIKALAAAAVLDETS +--SAQLDEVVRYKMSDLVPYSPVTGKHVADGMTLRALADAAVRYSDNTAGNLLLARLGGP +EGLERALRGIGDRVTEVARVEPDLNAATPGDVRDTSTARALATDLRAYALGDALSAEDRA +VLVDWLKGNATGATLIRAGVPAGWEVADKSGTGGYGTRNDIAVVWPTGGDPIVLAVLSRR +DDKDASYDDALIAQAAKVAVA-- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DE76B06 +-----EQIKISEGQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLHQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI00112349FB +----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAVAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A243ERY1_BACUK +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELANASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. RIFCSPHIGHO2_01_FULL_69_31 TaxID=1801944 RepID=A0A1G2W7J1_9CAUL +--AADAALADLEQRHGGRLGVVIWRPADGLRI-ARRADERFAMCSTFKTLAAAAVLARVD +RGREDLERRVVFGKDQVVTYSPVTGPRVGGDMTLAEICAAAIRFSDNTAGNLLLDSLGGP +AGLTRFARGLGDEITRLDRYETLLNEATPGDPRDTTSPDAMARNLRKLLLGPTLSSESRR +RLSQWMASNTTGDARIRRGIPTGWVVMDKTGAGENGANNDVAVILPPSGRPAIVTVYYAE +SQATGAQRNAVIADVARVAAR-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Yersinia intermedia TaxID=631 RepID=Q1W757_YERIN +--SLDKQLAALEHSANGRLGIAMINTGNCTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS +QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ +REKNAKPRRDVLA---------- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013D09F2D +-----PRFAALETTAGARLGVFAVDTGSERTV-AYRQDERFPMASTFKGLACGALLREHP +LSTGYFDQVIHFSAAELVEYSPVTETRVESGMTVAELCHAAITVSDNTAGNQLLKLLGGP +QGFTAFLRSLGDETSRLDRWETELNTAIPGDERDTTTPAALAADYRALVVGDVLGEPERA +QLTSWLVANTTGGSRIRAGLPADWTVGDKTGSPAYGSALDVAVAWPPGRAPIVIAVLSTK +SEQDAEPDNGLLADATRAVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0010BE7195 +----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar kim TaxID=180847 RepID=A0A243AES4_BACTU +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A443TI66_BACMY +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKGDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPAHKRN +ILTDWMKGNATGDKLIRAGVPTDWEVGDKSGAASYGTRNDIAIVWPPNRAPIIIAILSSR +DEKEATYDNQLIAEATEIIVNAf +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI000BE7006C +-----EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMVERNQQIAGIGAALIEHw +>[subseq from] Class A beta-lactamase n=1 Tax=Ensifer alkalisoli TaxID=1752398 RepID=A0A1E3V6B3_9RHIZ +-dDVAKQLEELEKRTGGRLGVSVLDTRTNISF-GHRETERFAMCSTFKALAAACALARVD +RGEEALDRRIAFGRDVLLPHSPVTGKHVGGNMTVAALCEAAITISDNAAANLLLESFGGP +AGLTSWLRSIGDEATRLDRMEPELNEAAFGDPRDTTTPAAMLETLRKLAFGSVLSESSRQ +RLVGWMVANKTGGARLRAGLPRDWRIGDKTGTSMAGAVSDIGFAWPDGRGPILVAVYTGE +AKAPLDALNPVFAEIGRIIA--- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=A0A221BYY2_BACCE +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=3 Tax=Bacillaceae TaxID=186817 RepID=A0A1Y0TYS1_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000B4B7061 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A4R3SDD7_9BACI +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIADAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseorubens TaxID=66897 RepID=A0A656REK9_9ACTN +------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDRRP +--GARLDERISYGAADLVPYSPVTEKHTGQGMTLRELCDAAVRYSDNTAGNLLLRDIGGP +RGLTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVHGDALPAAGRA +LLTDWLVRNTTGDDRIRAGVPRGWKVGDKTGTAEWGRANDVAVLWPGGGSPLVLSVLTDR +PDRDASGQDELVAEATRRVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora marina TaxID=307120 RepID=A0A1C4XDA7_9ACTN +-----QAFRLLEEKFDARLGVYAIDTGTGRTV-AYRPDERFAYASTYKALAAAEILDETT +--DTELDRVVRYSADDLVTYSPITEQHVATGMTLRAITDAAVRYSDNTAANLMLRHLGGP +QRFERELRGIGDKVTDPERYETELNEARPGDRRDTSTPRALAGSLRAYTVGDALEPPDRA +TLNDWLRRNTTGGALIRAGVPDGWVVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEKDADYDDALIAEATRVVTAGw +>[subseq from] Beta-lactamase n=1 Tax=Herbihabitans rhizosphaerae TaxID=1872711 RepID=A0A4Q7KMF8_9PSEU +--DLGQRFAALEQQYGARLGVYAINTRTGVTV-THRADERFPMCSTFKTLAAAAILRDRD +QHGEFLAKVIPYARADLVANSPVTEKHVGAGMRVDQLCAAAIQYSDNTAANLMLREIGGP +AGVTAFCRSIGDPATRLDRWETALNSALPGDPRDTTTPAAIGRDYDQLVLGRALSREDAA +LLTGWLCGNTTSSKRFRAGLPVGWRLGDKTGGGDYGTNNDVGVTWTTRGTPLVLVALSTR +HTQDAAPQDALLADTARLLA--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009ADABA7 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAAYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. NH11B TaxID=1866314 RepID=UPI0009F9BB65 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVINYTKDDLVEYSPVTEKHVDTGMTLGEIVEATVRSSDNTAGNILLNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNKAPIIIAILSSK +DEKEDTYDNQLIAEAAKVVIN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009E4E49E +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A160H0Y6_BACCE +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000B4DB372 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDASYNNALIAETAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000D3E1920 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDASYNNALIAETAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia silvatlantica TaxID=321895 RepID=UPI000D5CC207 +--SLEKPLAAIEAQAGGRLGVAMLDTANGHVR-GWRMQERFPMCSTFKVLLASAVLTRKD +HGKEDLARKIVYSPAQVVSYSPVSGPRAGSEMTVAELCEAALTRSDNTAANLLLESIGGP +AAITAFARSIGDPVTRLDRNETTLNDAIPGDPRDTTTPAAMVANLRELLLRERLASVSRE +QLIAWLVANKTGDARLRAGLPKDWRVGDKTGTGDHGTANDVAIIWPTGRAPILVTAYLTG +ATASPSQRDAAIAQVGV------ +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=A0A2S7BJL4_9XANT +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP +PGLTTFLRGIGDAHTRSDRREPEMNRYAEGDARDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGETCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A679H866_9BACI +----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar pakistani str. T13001 TaxID=527027 RepID=C3E3Q8_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYNNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=3 Tax=Xanthomonas TaxID=338 RepID=A0A1S1XKL8_9XANT +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRVD +QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP +AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2B3B8X7_BACTU +----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A1B1C4W1_RHILE +--NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENIDRRVSYGKDKLVDYSPISEKHADTDMTLAALCEAAVTVSDNTAGNLLLESFGGP +AGLTNWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGNIAVIWPPDRGPIVAAVYISE +TTVPVKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=2 Tax=Xanthomonas euvesicatoria TaxID=456327 RepID=UPI0004A21FA8 +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRVD +QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP +AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011445C1E +---TYKDFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKAIAAGVLLQKNS +--TEKLNEVITYTKEDLVDYSPVTEKHVGTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTLSDRFETELNEAIPGDNRDTSTAKAIATNLKNFTIGNALPDHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVN-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas graminis TaxID=158627 RepID=A0A1C2E2J1_9PSED +--AIAQQLAELERRHGGRLGVAILDTSSQRLI-SHRGDERFPLCSTFKCLAAACVLARVD +QKHEDLSRRIVYSAEQLVAYSPTTELHAGGQLSVGSLCEAAMTLSDNTAANLLLDSVGGP +EGLTAWLRSMGDTQTRLDRREPELNENRPDDLRDTTTPVAMLQTLNTLVLGEKLTPASRD +QLTAWLVNNQTGDKKLRAGVPVSWRVGDKTGSGANNASNDVAVIWPGERGPMLVTAYYTC +SKASGDQINALMTDIGRLAA--- +>[subseq from] Beta-lactamase n=2 Tax=Paludibacterium purpuratum TaxID=1144873 RepID=A0A4R7B2X1_9NEIS +-qAIRQHLSQLERSTNGRLGVALIDTADNSRV-GYRADERFPLCSTSKVMAAAALLKLSE +SQRGLMQRDIAIERSDLVNYNPVTEKYVGGRMTLAALSAAAVQYSDNVAMNKLIEQLGGP +QAVTRYSRTLGDRAFRLDRKEPGLNSAIPGDERDTTTPAAMAESLRKLTLGDALQAPQRE +QLVNWMKGSTTGAASIRAGLPASWAVGDKTGSGAYGTTNDIAVIWPTGRAPLILVTYFTQ +KAPKALARRDVLASAAHIVIQ-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000B430894 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAXXX-LQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKDLTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK +DEKEAAYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. OLGA172 TaxID=1804984 RepID=A0A160FUW9_9BURK +--AIRQRLAQIEVESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKLLAAGFVLTRVD +HGQEDLERRIVFSKSDLVPYSPATSQHTRERMSVADLCKAAMTLSDNTAANLLLASFGGP +SALTAFARSIGDGITRLDRNEPTLNEATPGDSRDTTTPNAMLGNLRELLLGERLSSSSRA +QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVTVYLTE +TSGDAARCNAASASVGALVA--- +>[subseq from] Beta-lactamase n=1 Tax=Reyranella sp. CPCC 100927 TaxID=2599616 RepID=A0A5C5SUV3_9PROT +------ACRRIEAKVGGRLGVAVMDTTSGTRA-SHRGGERFPILSTFKALACGAVLKRVD +DGKETLGRRIQYSAGDLVPHSPTTKAHVADGMTLADLCTATMTLSDNTAGNLILQALEGP +EGLTRFVRGLDDKITRLDRWEVALNEAATGDPRDTTTPDSMAENLRKLVLGDTLSASSRN +QLTAWLVANKTGDARLRAGLPKTWRVGDRTGTGDNGATNDVAVAWPPGRGPIIICVYLTE +TRAALDDRNAAIAAIGWTVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Marinobacter fonticola TaxID=2603215 RepID=UPI0011E88C9C +---FDEAMAEIESQNGGRLGVAVLDTASGERL-TYRANERFAMTSTFKWVLVAAVLSRVD +AGEDALDRQIQYDESDILSYAPIAKQHLPAGMTVAELSDAAIRYSDNTAANLLLETLGGP +AGLTAYIRTLGDDMTRLDRNEPGLNTNRPGDKRDTTTPAAMVGLMRLALVGDALSAASRQ +QLQDWLIRNTTGDTKLRAGLDPDWTVGDKTGAGDRGASNDVAIVWPKKGAPILIAVYYSG +TMLPNEALNAVHAEVGRVIAGVf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B52F65 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0012B9C763 +-----EQIKISEGQLAGRVGYVEMDLARGRMLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A5M8SFT9_BACCE +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SGFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A0G4D0X4_BACTO +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Chromobacterium sp. LK11 TaxID=1628212 RepID=A0A0J6NMN1_9NEIS +----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPLCSSFKGFLAAGVLAQSQ +QQPGLLDKRIRYSKTALPNWSPITTKQQANGMTVAELNAASVQYSDNGAANLLLKEINGP +AALTAFMRSIGDASFRLDRLEPELNSAIPGDPRDTSTPKAVAESMQKLALGKALPEAQRQ +QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH +AKKEAKHSNEVIAAAARAALEAf +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011A09D4B +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IATLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhizobacter sp. OV335 TaxID=1500264 RepID=A0A1M7ISV9_9BURK +---ADARWAAIEADVGGRLGAAVLDTGSGRVD-GHRLDERFPMCSTFKWLAASLVLQRVD +AGLERLDRRIVVRREVLIANSPVSEQHVGGDMSIAELCEATVLVSDNAAANLLLASFGGP +PAITRHARSLGDTKTRLDRTEPALNEARPGDPRDTTTPRSMATALRSALLGTALSDASRA +RLVAWMEAVRTGTDRLRAGLPPDWRVADKTGTGARGSTNDVAVAWPPNRAPLVITAYLTD +SKADAKRRNAALAAVAREAA--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RBZ2_9BACT +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQMGDNVPRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI24_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDXAVIWPENHAPLVLVTYFTQ +PQQDAK----------------- +>[subseq from] class A beta-lactamase n=1 Tax=Labrenzia sp. THAF35 TaxID=2587854 RepID=UPI00126887C3 +---LEKTVTGAESRLSARIGVAVLDTETGKTW-THRADERFPLNSTFKAFLCAALLEKGE +QGEVQPERRVKIRSQDLVSYSPVTEKKVGSGMTYLELCEAAVAISDNAAANLVLEAVGGP +AGLTDYLRGIGDTITRLDRTEPGLNEGRPGDARDTTTPAAAVATLQKLVLGDALSSTARA +QLTGWLLDNKVGNATLRAGLPEEWPVADKTGAGANGSRNNIGVIWPDDREPVVIAVYITQ +TDASFDDRNKAIADIAAALAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI000BF933F0 +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLIEIGDTVTNPERFEPELNEVYPGEIHDTSTPKALATSLQAFALGDILSTEKRN +LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A0J6ZMN3_BACCE +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus cereus TaxID=1396 RepID=R8S2C7_BACCE +----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8GCP6_9BACI +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVQKRN +ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPQNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Duganella sp. Leaf61 TaxID=1736227 RepID=A0A0Q4P523_9BURK +----AAQLARLEADTKGRLGVAAINTADGRIL-SHRGDERFPLCSSFKAMLAAAILQHEP +---SLLDKRIRYTAADLVSHSPVTEQNLADGMTVGELCAATIQYSDNAAANLLMKQIKGP +AGVTAYARSIGDKAFRLDRWETELNTAIPGDPRDTTTPLAMMKSLQSFTLGPALTVDKRN +LMTEWLIGNTTGDTRIRAGVPYDWQVGDKTGTGSYGSTIDIGVVWPAGKAPVVMALYFTQ +PGKDDKANSEILASAARVVVEAf +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI00111D8366 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=A0A1S9YVE7_BACCE +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001444039B +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] CRH family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A2T5NY59_9NEIS +----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPMCSSFKGFLAAGVLAQSQ +DKPSLLDKRIRYSKTALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLKEINGP +AALTAFMRSIGDASFRLDRREPELNSAIPGDPRDTSTPKAVAESAQKLALDKALPEPQRQ +QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH +AKKEAKHSDEVIAAAARAALEAf +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=J3ZVN2_BACTU +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=17 Tax=Bacillus TaxID=1386 RepID=A0A0Q0V245_BACTU +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0002794A92 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. SNU WT3 TaxID=2590869 RepID=A0A4Y6RJB9_9BURK +--AAHTQLAALEQAAGGRLGVAAWRQGSELRV-TYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMSVADLCAAALQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAHGSVNDIGVAYPPSGAPLVIAVYYTR +EQKKADTNQDIITAATRIVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF3109E +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0013314A7F +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. ZZV12-4809 TaxID=2575830 RepID=UPI00135A5632 +---TNQKFKQLEKKFDARLGVYAYDTGTKKKI-AYRSNERFAYASTFKPLAAAILLERKS +--LEEMDEIITYTSDDLVTYSPVTEKHVDTGMTLRELCEAAIRYSDNTAGNIILEELGGP +EGFKAALKEMGDTVTRPERFETDLNEAKPGDIQDTSTPKALAASLQKVLIGDFLTEEKRN +ILTDWMRGNATGDPLIRAGVPSGWEVADKSGAAGYGTRNDIAIIWPPDREPIIMTILSSR +KTKDAEFDNALIAEAAEMTIK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2B4BA30_BACTU +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus AH1272 TaxID=526993 RepID=C2Z896_BACCE +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000E23DE59 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNP +--IEKLNDIIRYTKEDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSFGTRNDIGIVWPPDRAPIVLAILSKR +FTKDANYDNALIAEAAKVAFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000992149D +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALVTSLKAYALGDILSIEKRN +FLIDLMKKNTTGDNLIRSGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Labrenzia sp. CP4 TaxID=1674922 RepID=UPI0007852749 +---LEKTVTGAESRLSARIGVAVLDTETGKTW-THRADERFPLNSTFKAFLCAALLEKGE +QGEVQPERRVKIRSQDLVSYSPVTEKKVGSGMTYLELCEAAVAISDNAAANLVLEAVGGP +AGLTDYLRGIGDTITRLDRTEPGLNEGRPGDARDTTTPAAAVATLQKLVLGDALSTTARA +QLTGWLLDNKVGNATLRAGLPEEWPVADKTGAGANGSRNNIGVIWPDDREPVVIAVYITQ +TDASFDDRNKAIADIAAALAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Burkholderia sp. CF099 TaxID=1882791 RepID=A0A658UKH1_9BURK +--ALEKQLAQIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD +QGKEQLGRTIAYSKEVVVANSPVSGPRAGDDMTVAELCEAAITRSDNTAANLLLDSIGGP +AALTAFARGIGDRITRLDRNEPTLNEAMEADPRDTTTPAAMLADMRALLLGGHLSAASRE +QLTAWLAGNKTGDARLRAGLPKAWRIGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG +ATATSTQRDAAIAQVGALVAN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. N35-10-4 TaxID=1866315 RepID=UPI0009F8121B +-qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGS +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKDLTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A5P9YC78_BACCE +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADNRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFMLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhizobium TaxID=2613769 RepID=UPI00072A49A8 +-nDIEQQLTALEKRTGGRLGVYVLDTKTKASF-AHRPDERFAMCSTFKALAAAFALARAD +KGEEKLDRRIPISKKHLLSYSPIVEKHVGGGMTVRELCDATVRYSDNAAGNLLLASFGGP +KGLTDWLRSIGDETTRLDRIEPELNEAKIGDPRDTTSPKAMTETLGKLLIGDVLSPASRD +QFSAWLVANTTGDRRLRAGLPKDWTIGEKTGTSGRGEAGDIGFMRPAEGHTILASVYIAE +GTKPTKELEPVFAEVGKLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Saccharomonospora azurea NA-128 TaxID=882081 RepID=H8G598_9PSEU +---VQGELRALEARHAARLGVYGINTRSGAVV-SYRAHERFPMCSTFKTLAAAAVLRDLD +RDGEVLDSWVHYTEDDLVVGSPVTERHVGTGMRVADLCAAAVSESDNTAANLLLDRIGGP +RGVTRFCRSLGDRLTRLDRYEPDLNSALPGDLRDTTTPAAIAEDYRRLVVGTALDRGDRA +RLTTWLTESVTSDTRFRAGLPSHWRVADKTGSGSYGTANDVGVAWTDDGTPLVLAVLSTK +HTPDAEWDDALVARTARVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF3FB10 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. ORS 285 TaxID=115808 RepID=A0A1Y6KF39_9BRAD +--DLQATIAGIETDSGGRLGVALLDTANAALS-GHRLDERFPMCSTFKALLAAAILTKVD +AGAEQLSRRLPITQADILSYAPVTKAYVGTSLSVGELCEAAVTLSDNTAANLLLATLGGP +AGLTRAVRGFGDAITRLDRIEPELNESVPGDPRDTTTPAAMAQTLAKLTTGNTLSAASRD +VLNGWLIGCKTGAARLRAGLPASWRVGDKTGTGDNGSSNDVAVIWPAGRAPVIVTSYLTE +TKAGDDKRNAVHAAVGRAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9BHS8_BACCE +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. S66 TaxID=1842608 RepID=A0A3B0A754_9BACI +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001155B6C9 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0011ED41C5 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Marinobacter hydrocarbonoclasticus TaxID=2743 RepID=A0A455W4T9_MARHY +hnALIKTVEKVADDLEALVGFAAYDLESDQRW-EYHADQRFAMSSTFKTLACAALLHRVD +AGQENLARKVNVSESDLVTYSPITEKHAGGEMTLSDLCEATLTTSDNTAANLVLRALGGP +EAVTSFARHLGDDVTRLDRWETELNEALPSDNRDTTTPNAMVRNLQALLLGNALSEPSRE +QLRDWLEGNQVAGGLFRAAVPEGWIVADRTGAGGFGSRSITAVIWPPERQPIVVALYLTQ +TDASFGERNAAIAEIGEAIV--- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora parva TaxID=1464048 RepID=UPI0004C200EF +------DFRQLEKRFGARLGVYAIDTGTGRTV-RYRADERFAYASTFKALAAAEILDETT +--DSELDRVVRYSADDLVTYSPITEQHVTEGMTLRAIADAAVRYSDNTAGNLLLRQLGGP +QKFEKELREVGDKVTDPARYETELNEARPGDRRDTSTAAALAEDLRAYAVGDALEPADRD +VLNGWLRGNTTGGDLIRAGVPDGWVVGDKTGAGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DQKDADYDDALIAQAAEVVI--- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus cereus TaxID=1396 RepID=A0A5S4HTN7_BACCE +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0A7HF61_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIRYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8R8_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQAAMDERNRQIAE--------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0A7HID4_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +TGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. Ab134 TaxID=1898042 RepID=UPI00117A42CF +--ELLDTVNRLEQEVGGRIGVVLQHTGSDWAI-ETRADERFPMASTFKALLCGAVLARVD +RGEERLGEVVAYSKAELVSYSPVTKKHVAEGMRVGELCEATVTMSDNTAANLLLKRVDGP +KGLTRFLRGLGDRVTRLDRREPEMNEAKPGDARDTTSPRAVVQTLDRLLFEEVLQPSSRA +QLQQWMVDDKVADALIRKHLPAGWRIADKSGGGYNGSRGIIAVIWSETGEAYLTAVYMTG +SNADFKKRNAVIAEIGKAIIE-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=A0A5R8NCK8_9NOCA +-----PRFAALETTAGARLGVFAVNTGSERTV-AHRADERFPMASTFKGLACGALLREHP +LSTGYFDQVIHYSAEELVDYSPVTETRVESGMTVAELCHAAITASDNTAGNQLLKLLGGP +QGFTAFLRSLGDDTSRLDRWETELNTAIPGDERDTTTPAALAADYRALVVGDVLGEPERA +QLTAWLVANTTGDTRIRAGLPEDWTVGDKTGSPAYGSALDVAVTWPSGRAPIVIAVLSTK +SEQDAEPDNRLVADATRTVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000E27098A +----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALTTDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=S3JEY9_BACCE +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000BA73C74 +----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALTTDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000B4DEBA8 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPEDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] Beta-lactamase n=13 Tax=Bacillus TaxID=1386 RepID=A0A5F0X974_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A249XB53_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD8C508 +-eDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +RGDETLDRRITYGREKLVTYSPETEKHAGGEMTLADICKAGITLSDNTAGNLMLESFGGP +AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSVLAEDSAN +RLVDWMVANTTGAARLRAGLPRDWRIGDKTGTGDNGAAGDIAIIWPPGRGPIVAAVYMAE +TTVKMDEFNPVFAEIGRMIAE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=J8K162_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=7 Tax=Bacillus TaxID=1386 RepID=A0A2A8E5G7_BACCE +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1S7F5Y6_BACTU +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8XRK6_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRTSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A4R1EGR5_BACCE +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIAEATKIVLD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. WAC 00631 TaxID=2203201 RepID=A0A428W3K6_9ACTN +--EASRRLRALESEHGARLGVFARNLDTGETV-VRRADERFPMCSLFKPVAAAAILRDHD +RRGEFLARRIRYGTTDLVEHSPITGKHVAQGMTVGELCDAAIRYSDNTAANLLLRELGGP +RAVTRFCRSVGDRTTRLDRWETELNSAEPWRVEDTTSPRAIARTYTRLIVGDTLSSADRE +RLTGWMLANTTSGERFRAGLPADWDLADKTGGGAYGTNNNAGVAWTPDRAPIVLAVLTTK +PAPDAAPDNELIAETAELLA--- +>[subseq from] Beta-lactamase Toho-1 n=1 Tax=Ensifer sp. M14 TaxID=2203782 RepID=A0A395LE97_9RHIZ +--DVDARLAELEKRTGGRLGVSVLDMDTNISF-GCREDERFAMCSSFKTLAAGFILARAD +QGAEKLDRRLVVAQKDIIAHSPITEKHVGGEMTIADLCASTMTTSDNAAANLLLESFGGP +QALTAWLRTIGDDTTRLDRNEPTLNEAKIGDPRDTTTPAAMLETLGNLAFGPALTEPSRK +LLIEWMVANTTGDQRIRAGLPKGWKVGDKTGTNSTGSASDIAIVWPEGRGPLLIAVYIAE +ATAPLAELNTVFADVGRMAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora pattaloongensis TaxID=405436 RepID=A0A1H3RXP3_9ACTN +--SAQRTFAQLEAGFDARLGVYAIDTGSGRTV-QHRADERFAYASTFKALLAAVILDVTS +--PAGLDRVIRYTEADLVTHSPITEQHVGEGMTLRALADAAVRYSDNTAANLLLRYLGGP +HRFEKALRAIGDRTTEADRYETALNEAVPGDKRDTSTPRALAADLRAYAVGRGLDRDDRD +ILNAWLRGNTTGDELIRAGVPDGWVVGDKTGAGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DQKDAGYDNALIAEATRLVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS094611 TaxID=2033516 RepID=A0A2A7DZH1_9BACI +--TVNHPFSKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHLGDTHDTSTPKALATSLQAFGLGDVLSTDKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDANYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase 1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=BLA1_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTEWMKGNATGDKLIRAGVPTDWVDADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C2VDV3_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A0J7HAJ3_9BACI +--ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRTSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2BY31_STRVZ +---ALRRLRALEESYPGRIGVHALHTGTGAVV-AYRADERFAIASTFKALLAAAVLRRAR +EEPGLLDVLIRYGRDDLVTHSPRTEMHLETGMTVRELCDATVTYSDNAAANLLMRRIGGP +VGVTEFARSLGDTRTRLDRWETDLNSNIPGDRRDTTTPAAMTANLRKLVLGKALHPLDRG +QLIRWLVENTTGDKRIRAGVPKDWRVGDKTGSPAYGGVNDVAVAWPPKQAPLVVSVYTTR +LDPDTPGEDRIAEDITRIVVD-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B8GC16_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGIRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. SSI4214 TaxID=2575739 RepID=UPI00143B62FC +--SLSLRINALEKRGGGRLGVAVLDTQDGRRF-AARGDERFLMCSTFKMLLAGLVLRRVD +QKRERLDRRVQYGPEVLVDYSPETKKHVGPGMTIANLCQAVITLSDNTAANLLLDAVDGP +VSVTRFARALGDPVTRLDRIEPALNTARPGDLRDTTSPKAMLETLRTLTVGDALTAESRA +RLVGWLVANQTGDARLRAGLPKTWKIGDKTGSDGRHTANDIAVIWPPGRAPLLITTYLTG +AKLDDDGRDAVLADVARAVVT-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=C2XBX2_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGIRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. KC721 TaxID=2530380 RepID=A0A4R4KQU3_9ACTN +---ASADFASLEQRFDATLGVYAIDTGTGRTL-AHRADERFAYASTVKALAAGALLDVTS +--DAELDRVVRYRRADLVTYSPITEQHVDTGMTLRAVADAAVRHSDNTAANLIFAELGGP +DGFERELREIGDTVTEPARIETALNEAAPGDVRDTSTPRAMATSLRAYALGDALSAADRA +VLVDWLRRNTTGAKLIRAGVPADWQVGDKTGSGGYGTRNDIAVLWPPRGAPIVLAVLSRR +DTKDAAYDDALIAEAAKLAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD92F26 +-nDINRQLASLEKRTGGRLGVSVLDTKSNVSF-GHRQDERFAMCSTVKALAAAFVLARVD +KGQETLGRRIDVSKADLHAHSPVAEKHVGDGMTVGELCDAAVTYSDNAAANLILASFGGP +AGLTAWLRSIGDETTRLDRTEPALNEAKPGDPRDTTTPAAMMRTLGKLLLEDVLSPSSRD +QFAAWLVANRTGDRRLRAGLPTNWTIGEKTGTSGHGEAGDVGFMRPPKSQTILASVYIAE +APKPVKELEPIFAEVGKLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000815F2E5 +----NDSFAKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDEKITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPKEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=UPI00064F4650 +--DLDETFATIESEYDARVGVYAIDTGSDQTI-DYRSEERFAFASTYKALAAALVLKQNT +--MEELEEVITYTEDDLVSYSPITEKHVDTGMTLAELSEAAVRTSDNTAGNLLFEELGGP +EQFQQSLREIGDDVTQSDRYETALNEFTPGNTRDTSTPIALATSLQGFAVGDLLTDDKRE +LLLDWMQGNATGDTLIRAGAPEGWTVADKSGAGRYGTRNDIAVVWPPNREPIILVIMTRH +DTEDAQYDDALIAEVAEVTLE-- +>[subseq from] class A beta-lactamase n=1 Tax=Lysobacter antibioticus TaxID=84531 RepID=UPI00055E55F4 +---WSAQLRVLEKNSGGRLGVGMLDTGSGQHF-DWRGRERFPMCSTFKFLLAAAVLREVE +RGKFDLEKKIPIAKSDLIAYSPVTEPLAGSSASVAQLCEATMTLSDNTAANLLLPLVGGP +AGLTAFLRGIGDPTTRLDRKEPELNSAIPGDPRDTTSPLAMVATMRKLLLQDGLKPASRQ +QLTSWLVANRTGDKRLRAGVPKGSRVGDKTGTADT-TSNDLAIIWLPERAPILLTCYLTG +STLDGPGRDAIHAAVARLVF--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0012AB6F53 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHITKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio denitrificans TaxID=258256 RepID=UPI000FFBEC5C +--ELLDTVNRLEQEVGGRIGVVLQHTGSDWAI-EARADERFPMASTFKALLCGAVLARVD +RGEERLGEVVAYSKAELVSYSPVTKKHVAEGMRVGELCEATVTMSDNTAANLLLKRVDGP +KGLTRFLRGLGDRVTRLDRREPEMNEANPGDARDTTSPRAVVQTLDRLLFEEVLQLASRA +QLQQWMVDDKVADALIRKHLPSDWRIADKSGAGHNGSRGIIAAIWPETGEPYLTAVYMTG +SDANFKKRNAVIAEIGKAIIE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. N113 TaxID=1703960 RepID=A0A192LTR1_9RHIZ +--NIEHRLAALEKRTGGRLGVSVLDTQTSISF-GYRASEAFPMCSTFKALAAGFVLARVD +KGQESLERRVTYGRDKLVDYSPLSEKHADTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +PALTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTAPDAMLDTLGNLTLGSVLAEPSSE +RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVKDLNPIFAEVGKMITE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2C3Z4M1_9BACI +--ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRTSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1G4L015_BACCE +----NDSFAKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDEKITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPKEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFA3FB9 +----NDSFAKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDEKITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPKEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus Rock4-2 TaxID=526987 RepID=C2WPJ9_BACCE +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGKTHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus TaxID=1386 RepID=UPI000DE92309 +---TYKEFFQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFSFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAAYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI00080C63B4 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKKP +--IEKLNDVIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKTFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR +FTKDANYDNALIAEAAKVALD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A243DAQ4_BACTU +-qATHKEFSQIEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. WMMA1996 TaxID=2039878 RepID=UPI000BF6DF10 +----DRAFRHLEETFDARLGVYAIDTGTGRTV-GYRADERFAYASTFKALAAAEVLDETT +--DAELDRVVRYSADDLVTYSPITEKHVADGMTLRALADAAVRYSDNTAGNLLLRRLGGP +QRFEKELRGVGDKVTAPARYETALNEARPGDRRDTSTARALAQDLRAYAVGDALDPADRD +ILNGWLRGNTTGGELIRAGVPDGWVVGDKTGSGGYGTRNDIAVVWPPDRAPIVLAVLSSR +DQKDADYDNALIARAAEVAI--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1E8BNH7_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI001117E61B +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDASYNNALIAETAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. MYb56 TaxID=1827287 RepID=A0A2S9I3C6_9BACI +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAAYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0013D2B4F1 +----NQKFVQFEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus siamensis TaxID=659243 RepID=UPI0012E7B5DE +---TNKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS +--NEKLNDIIRYTKDDLVTYSPITEKHLDTGMRLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALISEAAKAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI0010391485 +----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPEDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Fictibacillus phosphorivorans TaxID=1221500 RepID=A0A5P0YA13_9BACI +---TAKKFMQLEKKFDARLGIYAIDTHTNRTV-TYRPDERFAYTSTFKALASGLILQQKS +--IDKLNEVITYTEDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLKELGGP +NGFEKALREMGDNVTKADRYETDLNSAIPGDIRDTSTARALATNLKSFTVDDELPNDKRE +ILTDWLQRNTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPNRDPIIIAILSSR +DTQNATYENELIAKAAKVALNAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD81D17 +-eDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +RGDETLDRRITYGREKLVTYSPETEKHAGGEMTLADICKAGITLSDNTAGNLMLESFGGP +AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSVLAEDSAN +RLVDWMVANTTGAARLRAGLPRDWRIGDKTGTGDNGAASDIAIIWPPGRGPIVAAVYMAE +TTVKMDEFNPVFAEIGRMIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. Root133 TaxID=1736455 RepID=UPI0006F5DC2E +--DATQALAGLERRAGGRLGVAAWRRGGADVI-AWRGDERFPFCSTAKVMVVGTVLTLAA +RTPALLDERVRYKKADLVSWSPVTEQHVDDGMTIADLCAAALQVSDNSACNLLLDRIGGP +AAVTAFARRIGDTAFRLDRRETELNAAIPGDPRDTTTPRAMARSLEALLLEEALAPDARR +RLLDWMLANTTGKERIQAGFPADCRVADKTGTGAHGTTNDVGLVFPPQGQPVIVAVYYTG +SKSDS----KVVADAAAIVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium favelukesii TaxID=348824 RepID=W6R6G1_9RHIZ +-dEINRRIGALEKAIGGRIGVSAIDTQTNISF-GYRETERFPLSSTFKVLAAGLVLARVD +KGQETLERRVVYDQAKLVTYSPETEKHVGGEMSLSELCAAAITLSDNTAGNLLLESFGGP +PELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLALGSALSEPSRD +KLTEWMVANTTGGARLRAGLPGAWRIGDKTGTGNNGSAADIAIVWPPGHGAILVAAYVTQ +AKAPLSEINPVFAEVGRIVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI00111A540E +----NQKFVQLEKKFDARLGLYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=R8QDG0_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALVTSLKAYALGDILSIEKRN +FLIDLMKKNTTGDNLIRSGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=6 Tax=Xanthomonas TaxID=338 RepID=A0A0A3XJ82_XANCH +---LRAQWAQIERGTGGRLGVCLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP +AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTRWMIDNRTGDDCLRAGLAADWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces marokkonensis TaxID=324855 RepID=UPI0011F1FB0C +-------LAELEREYGARLGVYAVATGTGATV-IHRADERFAFCSVFKTLAAAAVLDRGP +--RARLDERVTYTRADLAAHSPVTERHADTGMTLRRLCDAAVRHSDNTAANLLLREVGGP +RAVTAYLRGLGDSVSRLDHYEPELNRNPPGDPRDTTTPRAVAADYRALVLGDALPAAERT +TLTDWLVRSTTGGRRIRAGVPRGWTVGDKTGTGSWGRANDVAVLWPGRGAPLVMAVMTDR +PGRDAAPSDALIAEAARRVL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BAG6O-2 TaxID=1053193 RepID=J9BEQ4_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE0DFD7 +-dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +KGDESLDRRITYGKDKLVTYSPETEKQAGGDMTMAEICKAAITLSDNTAGNLMLESFGGP +AALTDWLRSIGDGTTRLDRMETALNEATKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN +QLIDWMIANTTGGARLRAGLPGDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYIGE +ATVKMDEFNPVFAEIGKMITE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium freirei PRF 81 TaxID=363754 RepID=N6U0H5_9RHIZ +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GLRQEERFPLCSTYKALAAGFVLARVD +QGVEKLDRRVTYGKEVVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESVGGP +AALTSWLRVTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDTIGLLTLGNTLSETSRD +QLINWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAPAKDVEAVFAEVGKIIVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0005C87D2A +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Lysobacter enzymogenes TaxID=69 RepID=A0A1T3VJX5_LYSEN +-eALRAKLAELEKRSGGRLGVSALDTGDGRRF-DLRGDERFAMCSTFKFLLSAAVLHKVD +RGDLDLRQRIAVPKSALLPHAPFTAPIAEAGASVAQLCEATMTLSDNPAANLLLPLVGNP +AGLTRFLRGIGDAVTRLDRNEPELNTAIPGDPRDTTSPNAMLASMRTLLLGDALGAASRK +QLTDWLIANKTGDKRLRAGLPKDWRIGDKTGSGN-GTTNDIAIVWPTGRKPVFVVTYLTQ +ARGEDEQRSAILADCARALAERw +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013BE24D5 +----TPQFAELETTYDARLGVFAVDTGSGRSV-AHREGERFPMASTFKGLACGALLRDHP +LSTGYFDQVIHFPASDLVEYSPVTETRVETGMTVAELCDAAITVSDNTAGNQLLKLLGGP +EGFTAFLRSIGDNISRLDRWETELNTAIPGDERDTTTPAALAADYRTLVVGDTLAEPERA +QLTSWLVANTTGDTRIRAGLPGDWKVADKTGSPAYGSALDVAVTWPPGRAPIVIAVMSTK +SEQDAEPDNALLADATRAAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0012F5144E +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLHQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKV----- +>[subseq from] Beta-lactamase n=1 Tax=Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT) TaxID=572265 RepID=C4K574_HAMD5 +hqATIDKVKESERQLNARVGYVELDLANGQILnTYRPEERFPMMSTFKVLLCGAVLSRVD +AGLEQLDRRIKYRQSDLVKYSPMTKQHLADGMTVAELCSAAITVSDNTAANLLLSTIGGP +KGLTSFLQKTGDQVTRLDRWETELNQALPGDERDTTTPKIMAQTLHNLLTGKILSVKSRQ +QLQTWMVMNKVGGPLLRSVLPANWFIADKTGAGNHGSRGIIAALGADGKPSRIVVIYLTE +TQATMDERNKQIAEIGASLIKNw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus Rock3-28 TaxID=526983 RepID=C2UW73_BACCE +----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQQKS +--IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQDYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPREWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=A0A328NMN5_9ACTN +----DHEFRRLEERFDARLGVYAIDTGTGKTV-QYRAEERFAYASTFKALAAAEILDETT +--DAELDRVVRYSADDLVNYSPITEQHVAEGMTMRAIADAAVRYSDNTTANLMLRHLGGP +QKFEKELRKIGDKVTDPARYETELNEGRPGDRRDTSTPRAMAGSLRAYTVGDALEPTDRD +TLNGWLRGNTTGGALIRAGVPDGWVVGDKTGSGGYGTRNDIAVIWPPNRAPIILAVLSSR +DEKDADYDDALIAEATKVVMANw +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=C2WPN3_BACCE +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-53 n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A6A9RRF8_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Albidiferax sp. OV413 TaxID=1855285 RepID=A0A1H0SBA4_9BURK +--SASQQLQALETAATGRLGVAAFG-AGGASL-LHRAEERFPACSTFKLLLASAILARSA +QDPGLLQQRIRYTAADLVSYSPITEKHVADGQTVAELCAAALQYSDNSASNLLMRTLGGP +PAVTAYAHAIGDTSFRLDRWETDLNSAIPGDTHDTCTPAGMARSLQTLLLGDALALPQRT +QLKDWMLGNTTGATRIRAGVPADWRVADKTGAGSYGTTNDIGVVWSPAGTPVVLAVYFTQ +PDKGAPMRNDVVAATTRIAVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Aureimonas sp. D3 TaxID=1638164 RepID=UPI000786019A +--DLDALWAEIENRFSARLGAFVWDMETDRRW-ARRADERFPLCSTFKLVAAAGLLARVD +AGQENLSRRVVIAKSDLVTYSPETEKHVGGEMTLSSIAEAALSQSDNTAGNVLIDLLGGP +EGVTRTARGFGDESFRLDRRETALNEAKPGDPRDTTSPAAMTKTLHALLFGEALKPDSRR +QLADWMVANRTGDAKLRAGLPKDWRVGDKTGGGDFGTMNDVAVIWPPAGKPILVSLYLTE +TKASFDARNAAFAEVGRAL---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCBBF3 +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD +QGTEKLDRRVIYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPILVTTFVAE +ATASAKDIEAVFAEVSKIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ag82_G5-5 TaxID=2485160 RepID=A0A3N4UVE4_9ACTN +-----HQLHRLEHQHGARLGVFAHNVRTRKTV-AHRADERFPICSVFKTLTAGAVLRDLD +HDGEVLARRIHYTRADLVDGAPITDEHLANGMTVEELCDAAVRYSDNSAANLLLRLLGGP +TAITRFARSLGDRVTRLDRWEPELNSAEPGRITDTTSPRAIGRDYGRLVLGEALNRRDRD +LLTHWLLNNTTGANRIRRGLPDTWTVGDKTGSGSYGTTNDVGIAWTPEGAPIVLAVLSTT +PDQDRPWDDALIAEAAALVAD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F942_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSHVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLXAGLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=A0A1W6WPL7_BACTU +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Labrenzia aggregata TaxID=187304 RepID=UPI00094AE6AD +---LEKTVTGAESRLSARIGVAVLDTETGKTW-THRADERFPLNSTFKAFLCAALLEKGE +QGEVQPERRVKIRSQDLVSYSPVTEKKVGSGMTYLELCEAAVAISDNAAANLVLEAVGGP +EGLTDYLRGIGDTITRLDRTEPGLNEGRPGDARDTTTPAAAVATLQKLVLGNALSSTARA +QLTGWLLDNKVGNATLRAGLPEEWPVADKTGAGANGSRNNIGVIWPDDREPVVIAVYITQ +TDASFDDRNKAIADIAAALAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacteriaceae bacterium A-F18 TaxID=2045202 RepID=UPI0013EC2226 +-----ETVKKAEDQLNARVGYAELSLANGQMLgSYRPQERFPMTSTFKVLLCGAVLSRVD +AGQEQLARRIQYRKQDLVAYSPVTEKHLTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP +SALTAFLRKAGDRVTRLDRWETALNEALLGDERDTTTPEAMAQMLRQLLNGKILTPASQQ +QLMAWMEADKVGGPLIRSVMPAGWFIADKTGAGERGSRGIVAALGPDGKPARIVVIYITE +TQATMDDRNKKIADIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus haynesii TaxID=1925021 RepID=A0A1R1RJQ5_9BACI +-tEMKDDFAKLEEQFDAKLGIFALDTGTNQTV-TYRPDERFAFASTIKVLTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP +ESLKKELRKLGDEVTNPERYEPELNEVNPGETQDTSTARALATSLQAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPEGWDVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVIK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2B0SGY8_BACTU +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas citri pv. glycines str. 8ra TaxID=1401257 RepID=A0A1D9EGD0_XANCG +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLATYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A3A5HYD6_BACIU +----NHNFAKLEEEYDVKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEELNQRITYTREDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILKQLGGP +TGFKKALEEMGDDITNPERFEPDLNEVHPGETHDTSTPKALATSLQAFTLGDALPIEKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR +DKKDADYNDKLIAEATKEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium sp. WSM3879 TaxID=2029406 RepID=UPI000BB07203 +---ATKAVEALESRNGGRLGVMILDVGTNAAI-EYRADELFPMTSTFKFLAAAGVLKAVD +DGKAKLDDRIVYAASDVEPYSPITKDHVGEGMTLEDVCAAAVVWSDNTAGNLLLRVLGGP +QGLTRFARTLGDDVTRLDRTEPTLNTAIPGDKRDTTSPRALLGDARRILLGDALSPASRK +RLEAWLIEDKVGAARIRAGLPATWGIGDKTGSGDNGTTNIVAILWPPEGAPILVAVYYTG +STAPRASREAVHRDMARIIVETf +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax wautersii TaxID=1177982 RepID=A0A1I1ZDK8_9BURK +----RSGMQALEATLGARLGVAVLDTATGRAW-GWREDERFPMASTFKMALAGWMLALVD +QGRESLAQRVHFEREALVPYSPATEKHAGPGMTVGELCEAAVTLSDNTAANLLLARHGGP +AGYTAFLRSVGDEVTRLDRTEPALNEALPGDPRDTTTPAAMGRTLQRLALGDALSAASRA +QLMAWLVGNKTGDRRLRAGVP-GWRVGDKTGTGALGSSNDIGVLWPPGGAPLVVACYMTG +GAAAPAVRDAAIAQVARQAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A657V0B1_9BACI +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=6 Tax=Bacillus TaxID=1386 RepID=A0A2B9WY18_BACCE +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=R8L1P9_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKTLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKQN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKHDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Trinickia soli TaxID=380675 RepID=A0A2N7WGH8_9BURK +-kAIEAELASIERSVDGRLGVALLDMETGMRA-GHRVGERFPICSTFKLMLAANVLARVD +RGEENLERRIVFGQDRIDQYAPVTRERTGAPMTIAELCDAIVTMSDNTAANLLLDTVGGS +AGFTAFMRRLGDTVTRLDRNEPSLNEAIPGDPRDTTTPIAMLNDLREVLLGDALTAASRA +RLLAWGVGNRTGDTRLRAGVPGNWRVADKTGTGERGTTNDVGLLWPQERQPIVVTVYLTQ +SPAPVRAREAALADVARAIVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea vagans TaxID=470934 RepID=UPI0011C905C5 +-qTLTSQLETLESKSGGRLGLAVIDTADGSKY-AWRGNERFPLCSTSKVMAVAAILKKNE +RDPHLLDKKIHISKSDMVNYNPVTRKHIDSYMSVAELSAAALQYSDNAAMNKLLSYLGGP +QQATHFARTIGDKDFRLDRNEPGLNTAIPGDDRDTTTPSAMAESLKKVVLGTALKEEQRA +KLSDWMKGNTTGSDSIKAGLPDDWIVADKTGSGDYGSTNDIAVIWPKNHAPVILTTYFTQ +RDKDAATRKDVLASAAMLVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. MB366 TaxID=1663555 RepID=A0A1Q9KJ80_9BACI +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCEBBD +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEYFPLCSTYKALAVGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAAAKDVEAVFAEVSKIIVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis subsp. kyushuensis TaxID=44161 RepID=A0A243F4V0_BACTY +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. 61 TaxID=2035209 RepID=UPI000C710F73 +--AAHTQLAALEQAAGGRLGVAAWRQGSELRI-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATRIVAS-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudovibrio denitrificans TaxID=258256 RepID=A0A1I7BJ51_9RHOB +--ELLDTVNRLEQEVGGRIGVVLQHTGSDWAI-EARADERFPMASTFKALLCGAVLARVD +RGEERLGEVVAYSKAELVSYSPVTKKHVAEGMRVGELCEATVTMSDNTAANLLLKRVDGP +KGLTRFLRGLGDRVTRLDRREPEMNEANPGDARDTTSPRAVVQTLDRLLFEEVLQLASRA +QLQQWMVDDKVADALIRKHLPSDWRIADKSGAGHNGSRGIIAAIWPETGEPYLTAVYMTG +SDANFKKRNAVIAEIGKAIIE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. S-62 TaxID=2653123 RepID=A0A5J4M314_9RHIZ +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEYFPLCSTYKALAVGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAAAKDVEAVFAEVSKIIVD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium tumorigenes TaxID=2041385 RepID=A0A2W4BE57_9RHIZ +--DAGAQLAALEKRTGGRLGVAVLDTETNISL-GNRETERFPMFSTWKALAAGFVLARVD +QGKEKLDRRVSFGKEALVAYSPVAEKHAGTDMTIAELCEAAVTVSDNTAANLLLDSFGGP +AALTDWLRTTGDTETRLDRREPELNEAKKDDPRDTTTPDAMLDTLGLLTLGNTLSDASST +MLTGWLVAATTGKDRLRAGLPAEWKVGDKTGTGAQGMAADIAIVWPPERGPILVAAYITD +ATAPAAEINAVFAEIGKMVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. FJAT-29814 TaxID=1729688 RepID=UPI000834BEAE +--QLHREFAELENKYDARLGVYAIDTGTNRKV-SYRPQERFAYASTYKALAAGALLQHYS +--IDQLDELVTYNSEDIVSYSPVTQLHVDTGMTLREVAEAAVRYSDNTAGNLLLKKLGGP +EGFEKALRQIGDNITQVDRYETDLNSAIPGDNRDTSTPKALATSLKAFAVSDLLPTEKRA +ILTDWMRGNATGDALIRAGAPAGWVVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR +DTQNATYDNTLIAEAAKVALN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=B0LQI5_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDDRN-------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA2-1 TaxID=1053201 RepID=J9CI51_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAAYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B6RUS8_9BACI +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHIDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPLHKCN +ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEMIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. HNS054 TaxID=1662446 RepID=UPI000653A85B +------NLAALEREYGARLGVFAVDTGTGTTV-VHRADERFALCSTFKTLAAAAVLDRRP +--GARLDERITYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRHSDNTAANLLLRDIGGP +RGVTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALILGDALPAAGRA +LLTDWLVRNTTGDRRIRAGAPRGWKVGDKTGSGDWGRCNDVAVLWPGGGPPLMLSVLTER +PDRAASPSDELVAEAARRVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0B4ZZH9_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNR------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA2-9 TaxID=1053204 RepID=R8D0R0_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia dipogonis TaxID=1211383 RepID=A0A4Y8MQL2_9BURK +--AIRRRLAEIEAASGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKMLVAGAVLARTD +RGEENLQRRVVFSQSDVVSNSPATSKHTRELMSVAELCKAAITLSDNTAANLLLATFGGP +AGLTAFARGLGDGVTRLDRIEPTLNEGTPGDLRDTTTPNAMLGNLRELLLGERLSSSSRA +QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPVLVTVYLTE +TDGDAARSNAAIADVGALVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia mimosarum TaxID=312026 RepID=UPI00041523D8 +--AFEKQLAAIEAQVGGRLGVAMLDTASAHVR-GRRMHERFPMCSTFKLLLASAVLARKD +HGEEDLARRVVYSPAQVVSYSPVSGSRAGGEMTVAELCEAALTRSDNTAANLLLESVGGP +SAITAFARGLGDPLTRLDRNETSLNEAIPGDPRDTTTPAAMVANLHELLLGERLSAASRE +QLIAWLVANETGDARLRAGLPKEWRVGDKTGTGDRGTANDIAIVWPTGRAPILVATYLTG +ATASSAQCDAAIAKVGACLA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 5B6 TaxID=1127743 RepID=I2HPT2_9BACI +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDEMIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDASYNNALIAETAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000E4FC149 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] carbapenem-hydrolyzing class A beta-lactamase CRP-1 n=1 Tax=Chromobacterium piscinae TaxID=686831 RepID=UPI0005833D78 +---ADQKIARLERVFGGQIGVYALDTGSGAAV-SYRADERFPLCSSFKGFLAASALAHSQ +SKPGFLDQILHYGKEELIAWSPISEKHQSSGMTVAGLCAATVQYSDNAAANVLMKQLDGP +AGLTAFMRAIGDSTFRLDRWEPELNTAIPGDARDTSTPRAVAESLQKLTLGTALAAHQRQ +QLVDWLKGNTTGNQRIRAAVPAGWLVGDKTGTCGYGTANDYAVIWPTGRAPIVMAVYTRA +SKKDIKHSDAVIADAAKAALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Cyanobium sp. Copco_Reservoir_LC18 TaxID=1328305 RepID=UPI00135C96EF +--AAEAALAALEARSGGRLGVFAIDTASGARI-GHRAGERFPLCSTFKAILAGAVLHRSQ +RQPGFLEQRIRFGRQDLVSHSPVAEQHLEGGLTVAEMAAATVQTSDNTAANQLMARLGGP +AGLTAFARSIGNRTFRLDRWETALNSAIPGDPRDTDTPAGMGTSLQALVLGTALGPPQRQ +RLQDWLIGTTTGDRRVRAGVPSGWRVGDKTGTCGYGTANDVAVLWPPDRAPIVLAVFHTQ +ADPAAAAQDGVIAEAAAIVAGAf +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia caishijiensis TaxID=184756 RepID=UPI000833BA8D +----TTQFAALESKYGARLGLSVTDTGSGATV-AYRADERFPIASTFKGLACGALLQAHP +LSTGYFDQVVHYTAADLVEYSPETEKHVDTGMTVAALCHATITLSDNTAGNLVLRLLGGP +AGFTAFLRTLGDNVTRLDRWETELNTAVPGDERDTTTPAALAADYRALVVGNALAEPERA +QLAEWLKANTTGGKRIEAGLPADWIVGDKTGSPAYGSALDVAVAWPPNRPPLVLAVLSTK +SEQDAEPSNELLAEASRAAVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009955981 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLKKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=A0A1S1U7I8_9BURK +--AAHTQLAALEQAAGGRLGVAAWRHGSELRV-AYRADERFPLASTFKAILAAAVLARSV +SQPGLLDQHVRFEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGDVRDTASPASMAHSLQQLLLENSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLVIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Actinospica acidiphila TaxID=304899 RepID=UPI0013D8DEF3 +------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP +--GARLDERITYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRHSDNTAANLLLRDIGGP +RGVTAYARRLGDRVTRLDHTEPELNRNPPGDPRDTTTPRAIAADYRALILGDALPAAGRA +LLTDWLVRNTTGDRRIRAGAPRGWKVGDKTGSGEWGRCNDVAVLWPGGGPPLMLSVLTER +PDRAASPSDALVAEAARRVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. SG570 TaxID=2587113 RepID=UPI001445458C +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GYREEERFPLCSTYKALAVGFVLTRVD +QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCGAAITLSDNTAGNLLLQSFGGP +AALTSWLRSTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLINWLVGNTTGDNRLRAGLPKEWKVGDKTGTGNNGSFSDIAVVWPPDRGPILVTTFVAE +GTAPAKDIEAVFADVGKIVT--- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces albireticuli TaxID=1940 RepID=A0A1Z2LE20_9ACTN +----SLRLAELEREHDARVGVFGHHVRTGRTV-RYRAGETFPMCSVFKTLAAAAVLRDLD +RDGEFLAKRLRYTRQDVDEWAPETGKHIADGMTVAELCDAALTRSDNAAANLLLRELGGP +AAVTRFCRSVGDRTTRLDRWEPELNSAEPWRVEDTTTPYAIGRTYARLVLGNALSPRDRR +QLTAWLRANTTSDHRFREGLPAGWTLGDKTGTGDYGTANDVGIAWAPDGSPVVLAVLTTK +HTQEAKADDALIADVARLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A4U2NBZ4_BACCE +-----DSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEC0BBE +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYTSTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces alboniger TaxID=132473 RepID=A0A5J6HUU0_STRAD +--DARRRLRELEKGYPGRIGLHALNTGTGATL-GYRADERFAIASTFKVLAAAAILRRAR +EEPGLLDTVIRYGRDDLVTYSPRCEMHLATGMTVRELCDATVTYSDNAAGNLLMRRIGGP +SGITRFARSLGDPHTRLDRWETDLNTNIPGDPRDTTTPAAMTANLRKLVLGDALAPLDRD +QLIRWLVENTTGDARIRAGLPEGWRVGDKTGSPAYGGVNDIAVAWPPKGAPLIISVYTTR +LDPDTPGEDRIAADMTRVAVD-- +>[subseq from] Beta-lactamase (Putative hydrolase) n=1 Tax=Bacillus sp. 71 TaxID=593090 RepID=A0A654B0N2_9BACI +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPLILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. CB01635 TaxID=2020326 RepID=A0A2M9JS88_9ACTN +---ARRRLRELEAGYPGRIGVHALHTGTGAVL-AHRAHERFAIASTFKVLAASAILHRAR +QEPGLLDALIRYGRDDLVAASPRTEMHLETGMTVRELCDAAITYSDNTAANLLMRRIGGP +AGVTAFARSLGDSVTRLDRWETDLNTNIPGDRRDTTTPAAMTADLRALVLGDALHPLDRG +QLTRWLVENTTGDKRIRAGLPPGWRVGDKTGSPAYGGVNDVAVAWPPGGAPLVISVYTTR +LDADTPGEDRIAADITRIAVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI001115832F +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDEMIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDASYNNALIAETAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0010FBEB2D +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRTGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013BC3B98 +----TPQFAELETTYDARLGVFAVDTRSGRSV-SHREGERFPMASTFKGLACGALLRDHP +LSTGYFDQVIHFPASDLVEYSPVTETRVETGMTVAELCDAAITVSDNTAGNQLLKLLGGP +EGFTAFLRSIGDNISRLDRWETELNTAIPGDERDTTTPAALAADYRTLVVGDTLAEPERA +QLTSWLVANTTGDTRIRAGLPGDWKVADKTGSPAYGSALDVAVTWPPGRAPIVIAVMSTK +SEQDAEPDNALLADATRAAI--- +>[subseq from] inhibitor-resistant carbapenem-hydrolyzing class A beta-lactamase KPC-32 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00093994C8 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARYTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGMANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDD8B3B +-kDIDKQLAALEKQTGGRLGVYVLDTKTKASF-AHRQDERFAMCSTFKAVAAAFVLARVD +KGEERLDRRISISKKHLLSYSPVVEKHVGGGMTVGELCDATVTYSDNAAANLLLASFGGP +KGLTDWLRSIGDATTRLDRIEPELNEAKIGDPRDTTTPKAMTQTLGTLLLQDVLSPASRD +QFSAWLVANTTGDRRLRAGLPKAWTIGEKTGTSGRGEAGDIGFMRPVEGHTILASVYIAE +GKKPTEELEPVFGEVGKLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=E9NST5_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMAIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B0XSK5_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRTSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DDKEATYDNQLIAEAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus halodenitrificans TaxID=1482 RepID=UPI000761353D +----DEKFAEIEKEFNARLGVYAIDTGTNQRL-QYNPDDRFAYASTFKVLASAILLKQNS +--IEDLERVVTFSKDDLVTYSPVTEKHVDTGMTLGEISEAAIRYSDNTAANLLLEELGGP +EQFKQALRDLGDDVTQPERFETELNDFAPGKKRDTSTPKAMANTLKKVALDDFLPDDKRE +LLHNWMKGNATGDKLIRAGAPAEWVVGDKSGAGSYGTRNDIAIVWPPDREPIVIAVMSRH +EEADAEYDDALIAKAAEIALN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F5N2_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTERHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Labrenzia aggregata TaxID=187304 RepID=A0A0M6Y628_9RHOB +---LEKTVTGAESRLSARIGVAVLDTETGKTW-THRADERFPLNSTFKAFLCAALLEKGE +QGEVQPERRVKIRSQDLVSYSPVTEKKVGSGMTYLELCEAAVAISDNAAANLVLEAVGGP +AGLTDYLRGIGDTITRLDRTEPGLNEGRPGDARDTTTPAAAVATLQKLVLGNALSSTARA +QLTGWLLDNKVGNATLRAGLPEEWPVADKTGAGANGSRNNIGVIWPDDREPVVIAVYITQ +TDASFDDRNKAIADIAAALAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Saccharomonospora saliphila TaxID=369829 RepID=UPI0012FC4322 +----RARLHALERRHGARLGVYAANVRTGATV-SHRAGERFALCSTFKPLAAAAILRDRD +HHGEFLARTIHYTEHDLVEYSPVTEEHVGTGMRVDALCAAAIRYSDNTAGNLLLRQIGGP +AGLTAFCRSLGDPVTRLDRWETDLNSALPGDPRDTTTPAAIGRDYARLVLGDALGREDNA +LLTEWLLGNTTSGDRFRAGLPDGWRIGDKTGSGDYGTANDVGLAWTTLGTPLVLAVLSTK +HAPEADWDDELIAETARLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. Leaf406 TaxID=1736368 RepID=A0A0Q6L611_9BACI +-----ETFANIEDKYDARVGIYAIDTGSDRTI-DYRSEERFAFTSTYKALAAALVLKQNT +--MEELEEVITYTEDDLVSYSPITEKHVETGMTLAELSEAAVRTSDNTAGNLLFEELGGP +EQFKQSLREIGDDVTQADRYETALNEFTPGDPRDTSTPEALATSLQGFAVGDLLSDDKRK +ILIDWMKGNATGDTLIRAGAPEGWTVADKSGAGRYGTRNDIAVVWPPDREPIIMAIMTRH +DTEDADYDDALIAEVAEVTLE-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. RAU2J TaxID=1938810 RepID=A0A495TY53_9BURK +-eAIRERLARIEAASGGRLGVSIVDTTTSLHA-GLRADERFPMCSTFKLLAAGAVLTRVD +LGQEDLQRRVVFSASDLVPNSPGTSRHTRELMSIGELCKAALTLSDNTAANLLLASFGGP +AAVTAFARSLGDGITRLDRIEPALNEAIPGDPRDTTTPNAMLGNLRELVLGEHLSAASRT +QLLAWLVANQTGGSRLRAKLPEDWGVGDKTGTGERGTANDIAILWPPGRGPVLVTVYLTE +ADGDAARSNAAIANVGALVAE-- +>[subseq from] Beta-lactamase n=5 Tax=Bacillus TaxID=1386 RepID=A0A4D7HIG1_BACTU +----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNKVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYNDKLIADATKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. FT27W TaxID=2654636 RepID=UPI00128CD8E8 +----AAQLARLEADTRGRLGVAAINTADGRIL-SHRGDERFPLCSSFKAMLAAAILQHEP +---SLLDKRIRYTAADLVSHSPVTEQNLADGMTVGELCAATIQYSDNAAANLLMKQIKGP +AGVTAYARAIGDKAFRLDRWETELNTAIPGDPRDTTTPLAMMKSLQSFTLGPALTVDKRK +LMTEWLIGNTTGDTRIRAGVPYDWQVGDKTGTGSYGSTIDIGVVWPTGKAPVVIALYFTQ +PGKDDKANSEILASAARVVVEAf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. UNC322MFChir4.1 TaxID=1449045 RepID=UPI0009DF2EE5 +--ATHQEFAQLEKKFDARLGVYAIDTGTNRTV-SYKQNERFAFASTYKALAAGAVLLQNP +--IDKLNEVITYTKDDLVEYSPITEKYVDTGMTLGEIAEAAVRYSDNTAGNFLFKELDGP +KGFEKALKQIGDGVTQADRFETDLNEAIPGDIRDTSTAKALATDLKAFTVGNVLPADKRK +ILTDWMRRNATGDKLIRAGLPKDWEVADKSGAGSYGTRNDIAIVWPPNRKPIIIAILSSR +DTKDATYDNELIAQTATITIN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2C2T5T1_BACCE +--ATHQKYAQLEKKFDARLGIYAIDTGTNRTV-SYKQNERFAFASTYKALAAGALLMQNP +--IDKLNEVITYTKDDLVEYSPITEKYVDTGMTLGEIAEAAVRYSDNTAGNLLFKELGGP +EGFETALKQIGDRVTQADRFETDLNEAIPGDIRDTSTAKALATDLKAFTVGNALPADKRK +ILTDWMHGNATGDKLIRAGVPKDWEVADKSGAGSYGTRNDIAIVWPPNREPIIIAILSSR +DTKDATYDNELIAQAATITIN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. Leaf75 TaxID=1736235 RepID=A0A0Q6I169_9BACI +----KHHFVKLEDKFDARLGVFALDTSTNQTV-TYRADERFIYASTSKALAVGALLQQKT +--IDDLNQRITYTQDDLVNYNPITEKHVDTGMTLKELCDAALRYSDNTAMNLILKQIGGP +NGLEKSLRDVGDNVTMPEQFEPELNDVKPGETHDTSTPRALATSLQSFTLGDALPVEKRG +LLIDWMKRNTTGDSLIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPPKGDPIMLAILSSR +DKKDANYNDKLIAEATKEVINAy +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. GV004 TaxID=2135501 RepID=A0A2W7IKT7_9BURK +---AEAQLAELERACGGRLGVAGFHTASGARV-LHRAHERFPLCSTFKLMLSATVLERSA +KDPGLLSRRLRYGQADLIANSPVTEQHVATGMSVAELCAATLQYSDNAAANVLLRQLGGP +GEVTAFARRIGDAAFRLDRTEPELNTSIPGDPRDTTTPAAMSDSVQRLVLGDALGAPQRE +QLKAWLLGNTTSKERFLAGVPAGWKVADKTGAGSYGSNNDVGVLWPPAGAPLVLSVYLTF +AQKDAKTRNDVVAAATRIAV--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0012988D38 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGNKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacter rhizosphaerae TaxID=2010972 RepID=A0A561NXD1_9CAUL +----SRSIVALEARSGGRLGVAVLDTANGKTF-AHRGDERFAMCSTFKALVAGLVLKRVD +QGQERLDRRIPYGPGVLLAHSPATEKHVGQGMTVGALCEATVTLSDNAAANLLLHTFGGP +PALTAFLRGLGDTATRLDGYEPGLNVVRPGEIHDTTSPSAMLATLRALTLGPVLSAASRQ +QLVAWLVANQTGDKRLRAGLPAGWKVGDKTGSWSVGTTNDIAVTWPPRRPPLLITAYLSR +STLDDDGRNAVIAEVARLVAA-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2C1QKT9_BACTU +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATAVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000744C265 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVRPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI000E5BABC8 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALSNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas citri TaxID=346 RepID=UPI0006E57649 +--MLRARWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD +QGKLTLARQVKIRASDMLEHAPVTERHVGGSLSIGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGGPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia terpenica TaxID=455432 RepID=UPI0014282CE5 +---ADSEFASLETEYGARLGVYALDTGSGRTV-AHRADERFAYASTLKSLAAGAVLHAVP +--PAGLDERITYTRADLVPNSPVAEQHVDGGMTLRETLDAAVRYSDNTAANLLFAKLGGP +KGLERNLRDLGDTVTQVDRTEPDLNEATPGDPRDTSTPTAFAADLRQYVLGPVLTDPARA +LLADMLRANTTGAELIRAGVPAGWVVGDKTGLAAYGSRNDVAVLWPPNAAPIVLVVFTTR +PTEDATYDNALIAKAAAAAVQ-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000B42D680 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIAANLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. YIM 132548 TaxID=2615211 RepID=UPI00124723C3 +-eALRRHFAEIEGRSASRLGVAVLDRRTGLRA-GHRADERFPLCSTFKLLAAAAVLARVD +AGRESLERRVVFSAADLVPYSPATERRVGADMPLDEICAAAITLSDNTAGNLMLGAIDGP +AGLTAYLRSLGDPVTRLDRTEPDLNEARPGDPRDTTSPAAMLDTLQRLLLGPALSAASRA +RLVGWLRDNETGETRLRARLPRDWRVGDKTGTGENGTANDVGILSPPGGD-ILVAAYLTE +STAPSQARNATIAEVGQAL---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8XQ78_BACCE +----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5WWN2_9BACT +--DAAARVAAIEARIGGRIGVAALDTSNGKRF-DHRAEERFPMCSTFKFLAAAAVLKRVD +EKQEKLDRFVSYGAKDILEHAPVTKERLKDAMTLGALCEAAIEQSDNTAANLLLDAIGGP +ASLTQFARKLGDQITRLDRKEPDLNSAIAGDERDTTTPGAMCLDMQRLLVASVLSESSRR +QLEDWLLRNKTGGLMIRAGVPKTWSVGDKSGRCANGATNDIAIIRPPDRAPILLAIYSVG +STAPANNREMAIAEVAKIVAELf +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhizobium TaxID=2613769 RepID=UPI000A211530 +--NIEHRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGQESLERRVTYGRDKLVDYSPLSEKHADTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +PALTDWLRSIGDGTTRLDRTEPTLNEGRKEDPRDTTAPDAMLDTLGNLTLGSVLAEPSSE +RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVKDLNPIFAEVGKMITE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus mycoides TaxID=1405 RepID=A0A2B5QQ29_BACMY +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDTKYDDKLIANATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0006AD7971 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQTFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus lautus TaxID=1401 RepID=A0A385TW86_PAELA +-----------AAEDGIELSVGIQDLSGGGKI-QVGSSDVYYAASTIKIAIVTALMQDIE +AGKYALEQIIQVQPEQVVGGAGSLKDKFPLDITIESLARLMITQSDNTATNALIDLL-GF +ERINAFIEEQGFETMQLGRKMMTPAKS--PAADNYVDGEELLTLLERIYAGEILTAKSRD +QILAWMKAQEV-KTKFGAALP-GKPIAHKTGELGD-VSHDIGYFLVPGRE-AAVTVLTKV +TKKAQELGNPIVQRAAKAVYN-- +>[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus lautus TaxID=1401 RepID=A0A385TW86_PAELA +------------EDKGIRVSVGLKDLSGDREL-LLGSRQSYMPASTIKMALVSALMKEVD +AGRLTLEETVKVEKEDVVGGTGSLQKETPQDVTIERLAKLMITQSDNTATNVLIDVV-GL +DEVQNLMDELGLDVMHLGRKMFAAA--PTPEQDNYIDAEDLVHLLAYIHSGSFLSDNSRD +QIIDWMKAQEV-DTKFGAALP-DAPIAHKTGENAN-VTHDAGYFLLPGRE-IAISVLTEV +TTEAQAIGNPVVQEIAKAVYE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0U2TZA9_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000B454DE9 +----NDSFAKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. 75 TaxID=2135628 RepID=A0A4R8KLK0_9BURK +--AAHTQLAALEQAAGGRLGVAAWRQGSELRI-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATRIVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0G8ER34_BACCE +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Marinobacter sp. BW6 TaxID=2592624 RepID=A0A5D0VRR0_9ALTE +hsSLIQTVARIAGEIEAQVGFAAYDLESGQRW-EYQADQRFAMSSTFKTLACAALLHRVD +AGQESLERTVSFSESDLVTYSPITEKYAGGQMTLSDLCEAALTMSDNTAANLVLRALGGP +EKVTSFARDLGDDITRLDRWETELNAAVPGDNRDTTTPNAMVKSLQNLLLGDVLSGKSRD +QLHDWLKRNQVADGLFRAAVPEGWIVADRTGAGGFGSRSITAINWPPERQPIVVALYLTQ +TEASFSERNEAITEIGEAIV--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium fredii TaxID=380 RepID=UPI00059560EE +--DVTELLAELEKRTGGRLGVAVLDTETNTSF-GYRETERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGKDVLLPHSPVTEKHVGGEMTIAELCDAAITISDNAAGNLLLESFGGP +AGLTSWLRSIGDEATRLDRMEPDLNEASFGDPRDTTTPAAMIGTLGKLGFGSVLSESSRQ +QLIEWMVANTTGDARLRAGLPKSWRIGDKTGTSSTGAVSDIAFAGPEGRGPILIAVYTGE +AKLRPAELNPIFAEIGRIVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8X5_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQDDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATALRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Roseomonas mucosa TaxID=207340 RepID=A0A379MZJ5_9PROT +---LPAVFAGIERRVGGRLGVAVLDTATGQRA-GHREAERFPLTSTFKLLAAAAVLSRVD +AGQARLDQRIRYGREKLVAYSPETEKHAGEEMTLAAICEAAVTLSDNTAGNLMLEQIGGP +AGLTAWLRSIGDTVTRLDRWETALNEAEPGDPRDTTSPAAMLASLQRVTLGEALSVGGQA +HLTGWLRANKTGDKRLRAGLPGGWQAGDKTGVGERGTNNDAGLLWPPGEAPILVAAYSTG +GTAPSTERDAALAEVAAAIVA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8S3_9BACT +-----------EDQLGARVGYIELDLNGGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Caulobacter TaxID=2648921 RepID=A0A0Q6TXS4_9CAUL +--ALNSRINDLEQRSGGRLGVAVLDTQTGRRF-AWRGDDRFRMCSTFKMPLAAAVLRRVD +QGREQLDRRITYGRDVLMGNSPVVEKHLGEGMMVAALCEATITWSDNASANLLLDALGGP +ASLTRFLRAIGDQTTRCDRREPELNTGAPDDPRDTTTPSAILGTWKTLLLGDALSPASRK +QLTAWLVANRTGNKRLRAGLPRGWRVGDKTGNNGKDTTNDIAIAWPRGRKPILIAAFHDR +GSADDDARNAVHAELAHAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. NBRC 111119 TaxID=1661034 RepID=UPI0007618871 +--DIDSDLSTVEHSFKVTLGVWAIDTASGKTV-AYRAEDRFAFCSTFKVILAAAILAKSA +EDQALLDRRITYAPDQLVTYSPITEQHVQAGMTVRELCAAALQYSDNTAGNLLLELVGGP +PGLTAYARTLGDPAFRSDRNEPSLNTALPGDPRDTTTPLAMGVTLQKLLLGSGLAEGARQ +QLQGWLKGNTTGDKRIRAGVPQGWLVGDKTGSGDYGVANDVAVIWPPGKAPWIVVVFSRA +EAKASEWNNDAIAASMKAVV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8S8_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCGAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000CD93FE7 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGGLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKEFAVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKSAAEVVID-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00031461E4 +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGKTHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis YBT-1518 TaxID=529122 RepID=V5MB54_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IATLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNTTGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. J37 TaxID=935837 RepID=UPI0004799EE3 +---SQDEFSKLEEKYDAKLGVYALDTGTDETI-SYRPDERFAYASTSKALAVGVLLQQKS +--IEDLNEKITYSRDDLVTYSPITEEHVDTGMTLRDLSDASLRYSDNTAANLIFETIGGP +EEFKHALRQIGDDVTNPERMEPELNEVAPGETHDTSTAKALAASLQTFALEDALPPEKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAASYGTRNDIAIIWPPNEDPIVLTILSSR +NEKDAPYDDELIAEATKVVLAAf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA2-4 TaxID=1053203 RepID=J8CUJ7_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKLLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKNPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009B51DF1 +----NHNFAKLEEEYDVKLGVFALDTGTNQTV-TYHPDERFACASTHKALAVGALLQQKS +--IEELNQRITYTRGDLVNYNPITEKHVDTGMALKELADASLRYSDNTAGNLILKQLGGP +TGFKKALEEMGDNVTNPERFEPDLNEVHPGETHDTSTPKALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR +DKKDADYNDKLIAEATKVVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas phaseoli TaxID=1985254 RepID=UPI0003200A18 +--MLQAQWAQIERGTGGRLGVCLLDSATGKRL-GQREDERFPMCSTFKFVLVAAVLQRVD +QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP +AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTRWMIDNRTGDDCLRAGLAADWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. SLB01 TaxID=2610882 RepID=UPI001245E1B6 +--AAQTQLAALEKAAGGRLGVAAWRQGSDLRV-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLDQHVRYEKKDLVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAYARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATHIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=A0A0T9Q3R2_YERFR +--SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLVAAVLGHSQ +SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL +EMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTPPAAMAASVNKLVLGDALAAPQRE +QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWQAKGAPLVLVVYFTQ +LKKAAEPRRDVLAAATKIVLAH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8U3_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDGRDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. 64 TaxID=2035208 RepID=A0A2N0HYE9_9BURK +----HTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTMFQLERWETELNSAIPGEVRDTASPASMAHSLQQVLLGNSLPAAQRQ +QLDAWMRGNTTGDKRIRAGVPAGWKVADKTGSGAYGSVNDIGVAYPPSGAPLVIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=A0A423CK81_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERK-------------- +>[subseq from] Beta-lactamase n=1 Tax=Photorhabdus temperata TaxID=574560 RepID=A0A4R7Q3X4_PHOTE +--SLHQQLAELENSTKGRLGVTLINTANGQEI-QYRGNERFPFCSTFKLILVATVLHKSM +SQSKLLAKHINYHESDLLSYAPIAHKNLNQGMSITQLCAATLQYSDNTAANLLIKELGGV +EAVNHFTQSLGDPAFRLDRWEPDLNSAIPDDPRDTTTPAAMAASVKKIVLGETLAAPQRE +QLTVWLKGNTTGNASIRAGAPVGWVVGDKTGSGDYGTNNDVAVLWPPEGSPVILAVYFTQ +HQKDAESRRDVLASATRLVMAH- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. BCC1885 TaxID=2562669 RepID=UPI0011821F15 +--SVAAQLAKLEHEAGGRLGVCLLNTADGTWL-GHRADERFPFCSTFKVILSGAILARST +QTAGLLQRRIRYTQSDLVHYSPVSETHITDGMTVAELCAAALQYSDNTAANQLIKLLGGT +AAVTAYARLIGNDVFRLDRTETSLNDAVPGDPRDTATPASMVRSLQALTLGEALPVAQRA +QLIEWLRGNRTGAHRIAAALPAGWTIGDKTGTGDYGTANDLALIWPPARPPLVLGIYHTQ +AAQDAQPRDEVIAAAARIVV--- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI00044F85F2 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKPLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVPRLDRWETELNEALPGDARDTTPPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWVIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=J8AYM5_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF91AF9 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPEDVHDTSTPKALATSLQAFTLGDVLSTEKRN +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIALD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1G4EHS1_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0005C54B12 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IATLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNTTGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2A7VZV4_9BACI +--ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0009BE1196 +hqATYKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYAKEDLVDYSPVTEKHIDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPLHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEMIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=unclassified Bacillus TaxID=185979 RepID=UPI00124E32E6 +--ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. FJAT-27238 TaxID=1679167 RepID=A0A0K9MCT4_9BACI +---MDIKFAALENQFGARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP +--LEELDKVITYTKDDLVTYSPITEKHVATGMNLREVADAAVRYSDNTAGNLLFKELGGP +KGFESALRQMGDSVTTSERYETELNEAKPEDTRDTSTPKALATSLRAYTVGNALSSDKQK +ILIEWLQGNTTGAKLIRAGVPKDWIVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR +DKQDATYDDALIAEATKIAVD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2H2WCK0_BACCE +-qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRYSDNTAGNILFHKIGGP +KGFEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTIGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar vazensis TaxID=180867 RepID=A0A243CP90_BACTU +---VNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IENLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLIEIGDTVTNPERFEPELNEVHPGETHDTSTPKALATSLQAFALGDVLSTEKRN +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. X TaxID=2048901 RepID=A0A2G5REK9_9CAUL +-kALSSRINELERASGGRIGVAVLDTHDDRRF-AWRGDERFRMCSTIKAPLSAAILRRVD +QGRERLDRRVTYGPEVLMGNSPIVEKHVQDGMTIGQLCEATITLSDNAAANLLFEALGGP +AALTRFLRAVGDQTTRSDRPEPELNTGAPDDPRDTTTPAAMVATWKALLLDDALSPASRQ +QLRAWLIANKTGNRRLRAGLPRGWRVGDKTGNNGKDITNDVAIAWPPGREPVIIAAFHDR +GG-DDDARNSVHAEVARAIVA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus albus TaxID=2026189 RepID=A0A4Q0WSG1_9BACI +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--MEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLIEIGDTVTNPERFEPELNEVHPGEIHDTSTPKALATSLQAFALGDILSTEKRN +LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. HUB-I-004 TaxID=2568878 RepID=A0A4S4HTJ3_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYENALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKELTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWGVADKSGAGSYGTRNDIAIVWPPNKASIIIAILSSK +DEKGATYDNQLIAEAAEVIVNAf +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001145C5A0 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDPVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Candidatus Hamiltonella defensa TaxID=138072 RepID=UPI000BA295F9 +hqATIDKVKESERQLNARVGYVELDLANGQILnTYRPEERFPMMSTFKVLLCGAVLSRVD +AGLEQLDRRIKYRQNDLVKYSPMTKQHLADGMTVAELCSAAITVSDNTAANLLLSTIGGP +KGLTSFLQKTGDQVTRLDRWETELNQALPGDERDTTTPKIMAQTLHNLLTGKILSVKSRQ +QLQTWMVMNKVGGPLLRSVLPANWFIADKTGAGNHGSRGIIAALGADGKPSRIVVIYLTE +TQATMDERNKQIAEIGASLIKNw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FAB9_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKPGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Labrenzia sp. 011 TaxID=2171494 RepID=A0A2T7HB33_9RHOB +---LAAAVDHIGSRLPARVGVAVLDTETGKSW-SHLGDERFPLNSTFKAFLCAALLDKGE +AGDLDPGSRVKIHREDLVSYSPVTEKKVGSGMTLLELCEATVTISDNAAANLVFEQIGGP +DGLNGFLRRIGDMHTRLDRLEPGLNSGHPGDDRDTTTPVAAAATLEKLLLGDALSTGARA +QLIRWMEGNKVGDSTLRAGLPQEWRIADKTGAGGNGSRNDIGVIWPTGRAPVVIAVYITG +TSASFEARNAAIAEIGAALAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF56371 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Duganella sp. Leaf126 TaxID=1736266 RepID=A0A0Q5DM64_9BURK +----AAQLARLETDSKGRLGVAAINTADGAIL-SHRGDERFPLCSSFKAMLAAAILHQEP +---SLLDRRIRYKAADLVTYSPVTGQNLADGMTVGELCAAAIQYSDNTAANLLMKLVKGP +AGVTAFARTIGDKAFRLDRWETDLSTAIPGDPRDTTTPLAMMKSLQGVTLGPALTVDKRK +QLTEWLVGNTTGDTRIRAGVPFDWQVGDKTGTGAHGTTIDIGVVWPPGKAPVVMALYFTQ +PGRDDAANAEILAAAARVVVEAf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8VQV7_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSPRSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGQ------ +>[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella quasivariicola TaxID=2026240 RepID=UPI000E2CF52B +-----EQIKISESQLSGRVGYVEMDLASGRTLaAWRADERFPLTSTFKVLLCGAVLARVD +AGVERLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITMSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRRETQLNEALPGDVRDTTTPASMAATLRKLLTAKHLSARSQQ +QLVQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYMRD +TPATIAERNQQIAAIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001427AB38 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKTIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8S6_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAASLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. AC44/96 TaxID=1841654 RepID=A0A1B9SP10_9RHIZ +--EIDRRIGALEKAIGGRIGVSAIDTQTNISF-GYRETESFPMCSTFKVLAAGFVLARVD +KGEENLERRVVYDKDKLVTHSPETEKHVGGEMSVGELCQAAITQSDNTAGNLLLESFGGP +KELTNWLRTVGDGSTRLDRWETDLNEAKKGDQRDTTTPDAMLDTLGNLTLGSVLSEPSQN +KLVEWMVANTTGGTRLRTGLPDTWKIGDKTGTGNNGTAADIAVAWPPGHGPILMTVYVAD +ATAEISEINAIFGEVGRIAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI0011D0DC1F +--EIDRRIGALEKRIGGRIGVSVIDTQTNISF-GYRETETFPMFSTVKVLAAAMVLSRVD +KGEENLERRVVYDKSQLIDYSPETEKHIGGEMSVGELCKAAITLSDNTAANLLLETLGGP +KELTNWLRTLGDGSTRLDRIEPDLNEAKKDDPRDTTTPDAMLDTLGNLTLGTVLSEPSQN +TLVEWMVANTTGNERLRKGLPDGWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYINE +ATATTAEINPVFGEVAAIVAE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A3D9UT59_BACMY +---TYKEFFQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFSFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAAYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00046F965E +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADERFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH +DKEDAEYDDTLIADATKIVLE-- +>[subseq from] class A beta-lactamase n=1 Tax=Microtetraspora malaysiensis TaxID=161358 RepID=UPI000836A71B +------RLRALERKHGARLGVYALDTGTGGTV-AYRADERFAFCSTFKALAAAAVLHRNP +--LSHLDTRVTYTEADVNSISPITRDHVATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP +RKLTAYLRELGDSVSRMDNYEPELNSDRPKDPRDTTTPRAIASDYRELVLGDALTADKRA +LLKGWLVRNTTGDERIRAGLPKGWKVADKTGTGNYGRVNDIAVVWPPHAAPLVLAVMSDR +RGYNAPRENVLIAEAARQVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0007C1D88D +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRN +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A0B5S8D6_BACMY +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bordetella genomosp. 11 TaxID=1416808 RepID=A0A261UE73_9BORD +------EYAHLERAHRRRLGVYAVDTATGREV-TYRAHERFAFCSTFKAVLAGAILSQDA +AQPGLLDQRILYTAHELASYSPVTEKHVHGGMTIAQLCAAAIQYSDNTAANLLLHRLGGP +RALTAYARGLGNPTFRLDRFETALNTSIPGDERDTSTPADMARTLETLVLGDALPPGARA +RLKTWLLGNKTGDRRIRAAVPPGWQVADKTGTGDYASANDFGVIWPADRPPVVLAIYTAS +RDPHAKADESLIAEAARIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. MYb56 TaxID=1827287 RepID=A0A2S9I2B4_9BACI +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus penneri ATCC 35198 TaxID=471881 RepID=C0B2Q3_9GAMM +----------LKKYNQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE +KQAGLLDKNIAIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP +SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ +QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ +QEKDAKYRKDIIAKATEIVTKEf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BECE3D4 +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKAS +--IEDLDQIIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B3U3H6_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDFVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKLLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYNDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA2-1 TaxID=1053201 RepID=J9C1S8_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BAG5X1-1 TaxID=1053189 RepID=J8AYF6_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. DMF TaxID=400837 RepID=A0A4Y8NS21_9RHOB +--NTKQKFKKLEKEFDARLGVYAYDTGTKKTI-TYRSNERFAYASTFKPLAAAILLERKS +--LEELDEVITYTRDDLVTYSPVTEKHVKTGMTLRELCEAAIRFSDNTAGNLMLEELGGP +EGFEAALKEIGDTVTKPERFETDLNEAEPGDIRDTSTPKALAASLQKVLIGDFLTEEKRN +ILTEWMRGNATGDPLIRAGVPSGWEVADKSGAAGFGTRNDIAIVWPPNREPIIMTILSSR +DSKDAEYDNALIAEAAEMTIK-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. Leaf453 TaxID=1736380 RepID=A0A0Q6H772_9RHIZ +--DADVRLAALEKATGGRLGVSVIDVAMNISF-GRRQDERFAMCSTFKMLAAACILARVD +NGEERLDRKIAYSKADLVDYSPMTENHTEDGMTVAELCEAAVTVSDNTAANLLLASMDGP +EGLTRWLRGIDDQVTRLDRIEPELNEAKKDDPRDTTTPHAMLTTMGKLLLDDALSEKSRD +QLTAWLVGNKTGDKRLRAGLPKGWTVGDKTGTSATGAIGDVAIVWPSPNRPILITAYIAE +ATKPAKELEYIFAEIGKMV---- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000E0A5B5C +------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP +--GARLDERITYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRHSDNTAANLLLRDIGGP +RGVTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALILGDALPAAGRA +LLTDWLVRNTTGDRRIRAGAPRGWKVGDKTGSGEWGRCNDVAVLWPGGGPPLMLSVLTER +PDRAASPSDELVAEAARRVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter freundii TaxID=546 RepID=A0A1B3ISJ2_CITFR +----------------------NWDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus luti TaxID=2026191 RepID=UPI00124D7F77 +----NDSFAKLEKEFDAKLGIYALDTGTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYNREDLVNYNPITEKYVDAGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDIVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Limnobaculum parvum TaxID=2172103 RepID=A0A2Y9TV69_9ENTR +---IQHNLADLEKSTGGRLGVVLINTADNSRI-AYRGDERFPMCSTSKMMVVSGVLKQSE +VQKDLLNKQVDIRESDLVNYNPITEKRLNTKMSLAELSAATLQYSDNAAMNKLIAQLGGT +KKATAFARSIGDTAFRLDRTEPTLNTAIPGDKRDTTTPLAMAASLQKLTLGDALAAPQRA +QLVEWLKGNTTGAASIRAGLPAEWVVGDKTGSGSYGTTNDIAVIWPKDKAPLILVTYFTQ +NDKEAESRREVLASAAKIVTQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium TaxID=379 RepID=UPI000648410E +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GYREEERFPLCSTYKALAVGFVLTRVD +QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCGAAITLSDNTAGNLLLQSFGGP +AALTSWLRSTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLINWLVGNTTGDNRLRAGLPKEWKVGDKTGTGNNGSFADIAVVWPPDRGPILVTTFVAE +GTAPAKDIEAVFADVGKIVT--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus sp. 491mf TaxID=1761755 RepID=A0A1I1HUZ8_9BACI +--ATHQEFAQLEKKFDARLGVYAIDTGTNRTV-SYKQNERFAFASTYKALAAGAVLLQNP +--IDKLNEVITYTKDDLVEYSPITEKYVDTGMTLGEIAEAAVRYSDNTAGNFLFKELDGP +KGFEKALKQIGDGVTQADRFETDLNEAIPGDIRDTSTAKALATDLKAFTVGNVLPADKRK +ILTDWMRGNATGDKLIRAGLPKDWEVADKSGAGSYGTRNDIAIVWPPNRKPIIIAILSSR +DTKDATYDNELIAQTATITIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus pseudomycoides TaxID=64104 RepID=UPI000BECCF80 +--TVNHSFAKLEKEFDAKLGIYALDTGTNQIV-TYRSDERFAYASTHKALAVGVLLQKKS +--IEDLDERIVYTSEELVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRAIGDTITNPERFEPELNEVPPGDTHDTSTPKALATSLQAFALGDVLSTEKRE +LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus albus TaxID=2026189 RepID=A0A1J9UUJ4_9BACI +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKRSLIEIGDTVTNPERFEPELNEVHPGEIHDTSTPKALATSLQAFALGDILSTEKRN +LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=A0A4V7TLS1_BACAM +----KQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNP +--IEKLNNVIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR +FTKDVNYDNALIAEAAKVALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. 9096 TaxID=1500894 RepID=UPI0005694A80 +------GFAALEREFGGELGVAAIDGASGRTI-GYRQDRRFPMCSTFKTVLVAAILACAE +REPGLLERQVALPKQVFVNYSPVTGKHAGGALSVAELCAAALQYSDNTAANALLREVNGP +AALTRYARTLGDTDFRLDRWETELNSAIPGDPRDTTTPLAMARTLRTLLLGDGLAPDAQA +RLRAWMLGNTTGKDRIRAAAPAGWKVADKTGTGSYGSAGDIAVLFPPQRAPVVLAIYTRR +AAKDAQGRSDIIARAARIALE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A1E8ALW7_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK +LLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas axonopodis pv. vasculorum TaxID=325777 RepID=A0A098PXI9_9XANT +--ELREQWARIEQGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQQVKIHTSDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTALLRGIGDARTRTDRYEPQMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAQAVAAWw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001427A948 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2A8QC79_BACCE +----NDSFAKLEKEYDAKLGIYALDTGTNQTF-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDEKITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPKEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A454M7S1_BACTU +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFASGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Marinobacter persicus TaxID=930118 RepID=A0A1I3SAM0_9ALTE +--SLIKTVERIADELGARVGFSAYDVESDQHW-EYHADQRFAMSSTFKTLACAALLQRVD +AGQENLDRKVSFSESDLVTYSPVTEKYAGGQLTLSDLCEAALTMSDNTAANLILRVLGGP +AQVTSFARGLGDGVTRLDRWETELNEAAPSDQRDTTTPNAMVKNLQSLLLGDALSVKSRD +QLRDWLERNQVADGLFRAVVPEGWIVADRTGAGGFGSRSITAIIWPPERQPIIVALYLTE +TEASFSKRNDAIAEIGKALI--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000E4B10E6 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD115 TaxID=1053230 RepID=J8KM50_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRDIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYVLGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Alteromonadaceae bacterium TaxID=1916082 RepID=A0A2E5MQ19_9ALTE +---LIATVDRTANELQANVGFAAYDLESGQRW-EYQADQRFPLSSTFKTLACAALLHRVD +AGDENLDREVSVSKSDIVTYSPVTETFAGGQMTLAALCEAALTMSDNTAANLILRALGGP +AEVTAFARFLKDDVTRLDRWETELNDAAPGDQRDTTTPNAMVKNLQSLLLGDVLSTESRA +QLLDWLERNQVADGLFRAVVPEGWVVADRTGAGGFGSRSITAIIWPPEREPIIVALYITQ +TDASFPARNEAIAEIGKAIV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 5mfcol3.1 TaxID=1761756 RepID=A0A1I4CVE9_9BACI +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +GEKEASYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF44ACF +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPSNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0007E08E73 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPKHFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKKNTTGDSLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIALD-- +>[subseq from] Beta-lactamase n=2 Tax=Variovorax TaxID=34072 RepID=A0A0P9AEC2_VARPD +--DAEARLAALERDCGGRLGVHALDTASGARI-AHRGNELFPMCSTFKLMLAAAILQRGT +AEPALLERRLSYTRAHLLPNSPITEKHLADGMTVAELCAATLQYSDNAAANLLLHQLGGP +AGVTAYARSIGDTVFRLDRWETELNSAIPGDPRDTTSPAAMAASVQRLVLGDALAAPQRA +RLEAWLRGNTTSKERFLAGVPAGWAVGDKTGAGDYGTNNDVGVLWPASGAPLVLAVYLTF +PGKGAKTRNDVVASAVRIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus caeni TaxID=405946 RepID=A0A0N0M595_9BACI +--KIDNQFSQLEEEFDAELGVYAVDTETNQAI-EYQSEERFAFASTYKALAAAIVLQQNS +--MEELNQVITYTKEDLVPYSPVTEKHVDSGMTLLNLAEAAVRTSDNTAGNLLFNAIGGP +KEFEQTLREIGDNDTQAERYEPDLNQFSPEDPRDTSTPKALATSLQAFALGDLLPNEKRE +QFTDWLQGNATGDTLIRAGAPEGWEVGDKSGAGSYGTRNDIAVVWPPNREPIVIAIMSRH +DTEDATYDDALIAEAVKIALN-- +>[subseq from] Beta-lactamase SHV-1 n=2 Tax=Klebsiella TaxID=570 RepID=A0A6C2V8W7_9ENTR +-----EQIKISESQLSGRVGYVEMDLASGRTLaAWRADERFPLTSTFKVLLCGAVLARVD +AGVERLDRRIHYRQQDLVAYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLDTLGGP +AGLTAFLRTIGDNVTRLDRRETQLNEALPGDVRDTTTPASMAATLRKLLTAKHLSARSQQ +QLVQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYMRD +TPATIAERNQQIAAIGAALIEHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F966_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIAVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella TaxID=570 RepID=B4YF43_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGAA----- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI001145431F +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0013D07DCF +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00065BCA48 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001290702E +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--INSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS059628 TaxID=2033508 RepID=A0A2B4FK75_9BACI +-qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVINFSKEDLVDYSPVTEKHVDTGMTLGKIAEAAVRYSDNTAGNILFHQIGGP +KGYENALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPIQKRN +ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSNK +DEKGATYDNQLIAEAAEVVVNAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDF781A +--DIDKRLAALETRIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +KGDEKLDRRVTYGKDKLVTYSPETEKHAGGEMTMAEICKAGITLSDNTAGNLMLESFGGP +AGLTDWLRSVGDGTTRLDRMETALNEATKGDPRDTTTPDAMLDTLGNIALGSVLAEDSAN +QLVDWMVANTTGGARLRAGLPSGWKIGDKTGTGDNGSAGDIAIIWPPNRGPIVAAVYMAE +MTVKMDEFNPVFAEIGKMITE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDED4F2 +--DIDKRLAALETRIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +KGDEKLDRRVTYGKDKLVTYSPETEKHAGGEMTMAEICKAGITLSDNTAGNLMLESFGGP +AGLTDWLRSVGDGTTRLDRMETALNEATKGDPRDTTTPDAMLDTLGNIALGSVLAEDSAN +QLVDWMVANTTGGARLRAGLPSGWKIGDKTGTGDNGSAGDIAIIWPPNRGPIVAAVYMAE +MTVKMDEFNPVFAEIGKMITE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF58519 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAAGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2CSH4_STRVZ +--DAARRLRALEESYPGRIGVHALHTGTGAVV-AYRADERFAIASTFKVLAAAAILRRAR +EEPGLLDVLIRYGRDDLITYSPRTEMHLETGMTVRELCDATITYSDNSAANLLMRRIGGP +AGVTEFARSLGDSRTRLDRWETDLNTNIPGDRRDTTTPAAMTANLRKLVLGKALHPLDRG +QLTRWLVENTTGDKRIRAGVPKEWRVGDKTGSPAYGGVNDVAVAWPPKQAPLVISVYTTR +LDPDTPGEDRIAEDITRIAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium americanum CCGM7 TaxID=1408224 RepID=A0A1L3L1C2_9RHIZ +--DVTKLLAELEKRTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACVLARVD +RGEEKLDRRITFGKDVLLPHSPVAEKHVGGDMTVAELCDAAVTISDNAAANLLLESFGGP +AGLTSWLRSIGDRTTRLDRTEPDLNEAKFGDPRDTTTPVAMLETIGKLAFGSVLAESSRR +QLVEWMVANTTGDARLRAGLPKDWQIGDKTGTSSTGAVSDIGFAVPKGRGPILITVYTGE +AKVEPAELNPVFAEVGKIVA--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2K8TR97_BACCE +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQSFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B401C1 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTVKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRSGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNKLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00119CB1E0 +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQKS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8V7_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGLLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI0014197402 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGISLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=2 Tax=Phyllobacteriaceae TaxID=69277 RepID=Q11G68_CHESB +----SERLAALEKRSGGRLGVAILDTRTGLKA-THRADERFAMCSTFKALAAAAVLARAD +AGKEDLNRRISYGREKLIFWSPVTKNHADGPMTLAELCEAAVTMSDNTAGNLLLESLGGP +KGLTAFFRSLGDEVSRLDRWEPELNDVPPGDLRDTTTPEAMLGSLRSVVLGDALSPNSRQ +RLAGWLIGCKTGDKRLRAGFPAGWTVGDKTGTGST-VASDIAVAWARSGATLVVSAYLEA +PQLPAPKRDGIFREIGEIAS--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA4-10 TaxID=1053206 RepID=J8DP84_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodoferax sp. YR267 TaxID=2135500 RepID=A0A2U0YV57_9BURK +--SASQQLQALETAAAGRLGVAAFGAGSARLL--HRAGERFPACSTFKLVLASAILARSV +QDTGLLQQRIHYAASDLVSYSPITEKHVASGQTVAELCAAALQYSDNSASNLLMRLLGGP +PAVTAFAHAIGDSSFRLDRWETDLNSAIPGDPRDTCTPAGMAHSLQALLLGDALALPQRR +QLKDWMLGNTTGATRIRAGVPADWRVADKTGAGSYGTTNDIGVVWSPAGTPVVLAIYFTQ +PYQSAPMRNDVVAAATRIALQ-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A243FFN1_BACTY +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIAEVTEVIVK-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000CF39861 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPFMSTGKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLITTIGGP +KELTAFMHNMGDHVTRFDRYYGELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola pv. guizotiae TaxID=487867 RepID=A0A2S7A6K2_9XANT +---LRAQWAEIERGSGGRLGISLLDSATGKRL-GRREDERFPMCSTFKFVLAAAVLQRVD +KGELTLAHRITIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGVTAFLRGIGDAHTRSDRHEPEMNRFALDDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGATCLRAGLPRGWKIGDKTGSNGSDTRNDIAIVWPPAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. 166amftsu TaxID=1761753 RepID=UPI000B8234AF +--ATHQKYAQLEKKFDARLGIYAIDTGTNRTV-SYKQNERFAFASTYKALAAGALLMQNP +--IDKLNEVITYTKDDLVEYSPITEKYVDTGMTLGEIAEAAVRYSDNTAGNLLFKELGGP +EGFETALKQIGDRVTQADRFETDLNEAIPGDIRDTSTAKALANDLKAFTVGNALPADKRK +ILTDWMHGNATGDKLIRAGVPKDWEVADKSGAGSYGTRNDIAIVWPPNREPIIIAILSSR +DTKDATYDNELIAQAATITIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFC1FD0 +-----DSFVKLEKEFDAKLGIYALDTDMNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVVAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001443D68E +----DNSFAKLEKEYDAKLGIYALDTGTNQTV-SYRSDDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKTVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000B44EA1A +----DNSFAKLEKEYDAKLGIYALDTGTNQTV-SYRSDDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKTVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00124EFB29 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQSFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1C4DFB1_BACMY +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKQN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00114577AF +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGIRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF735B0 +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLVILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus cereus TaxID=1396 RepID=Q81DA0_BACCR +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2C4Q2K0_9BACI +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus oncorhynchi TaxID=545501 RepID=A0A0A1MQB6_9BACI +---SEEVFKELEDEFDTRLGVYAIDTETNQTV-AYRADERFAYASTFKVLAAAAILQTAS +--REDLEKVITYTEDELVTYSPVTENHVDDGMKLKEIMEAAIRYSDNTAGNLLLEELGGP +DGLEERLREIGDETIEADRMEPDLNEAAPGDTKDTSTPKALAESLQKYVLSDLLSEDKRD +LLTDWMTGNESGDTLIRAGVPEGWEVIDKSGAGGYGTRNDIAVVWPPDHAPIVISILSSR +DTEDADFDDAVIAKAARGVIE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2T0DNI3_9BACI +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A5C1FVF3_BACMY +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSNERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKTLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIMLAILSNH +AKEDAKYDDKLIADATKVVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001145DEA4 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGIPTDWVVGDKSGAGSYGIRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI001111F53B +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRVPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1G6IFW2_BACCE +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPEHFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKKNTTGDSLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Chelativorans multitrophicus TaxID=449973 RepID=UPI00140C5E4B +----SERLAALEKRSGGRLGVAILDTRTGLKA-THRADERFAMCSTFKALAAAAVLARAD +AGKEDLNRRISYGREKLIFWSPVTKNHADGPMTLAELCEAAVTMSDNTAGNLLLESLGGP +KGLTAFFRSLGDEVSRLDRWEPELNDVPPGDLRDTTTPEAMLGSLRSVVLGDALSPNSRQ +RLAGWLIGCKTGDKRLRAGFPAGWTVGDKTGTGST-VASDIAVAWARSGATLVVSAYLEA +PQLPAPKRDGIFREIGEIAS--- +>[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI001438455E +-----EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGDP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0006203D79 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=A0A2L2K0E5_9NOCA +------RFAELETTAGARVGVFAVDTGSERTV-AHREHERFPMASTFKGLACGALLREHP +LSTGYFDQVIHFSAAELVEYSPVTETRVETGMTVAELCDAAITVSDNTAGNQLLKLLGGP +QGFTAFLRSLGDDTSRLDRWETELNTAIPGDERDTTTPAALAADYRALVVDDVLGEPERA +QLTSWLVANTTGGTRIRAGLPADWTVGDKTGSPAYGSALDVAVAWPPGRAPIVIAVLTTK +SEQDAEPDNELVADATRAVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI0009CE5FF3 +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG +AKVNDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus TaxID=1386 RepID=UPI0005CB7D6D +-qETYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A141RQC0_9BACT +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A521NT36_9BURK +--DAEARLAALERDCGGRLGVHALDTGSGARI-AHRGNELFPMCSTFKLMLAAAILQRGT +AEPALLERRLSYTRAHLLPNSPITEKHLADGMTVAELCAATLQYSDNAAANLLMHQLGGP +AGVTAYARAIGDTVFRLDRWETELNSAIPGDPRDTTSPAAMAASVQRLVLGDALAAPQRA +RLEAWLRGNTTSKERFLAGVPAGWTVGDKTGAGDYGTNNDVGVLWPASGAPLVLAVYLTF +PGKGAKTRNDVVASAVRIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. L-9-10 TaxID=1478131 RepID=A0A4V1VMC8_9ACTN +----AGELKELERTFDARLGVYAIDTGTGREV-AYRDGERFGYASTFKALAAGAVLRKYS +--LSGMDRVITYSKEDLVANSPVTEKHVETGMSLKELCDATIRYSDNTAANLLFDQLGGP +KGLQAVLRGIGDDVTLMERREPELSRWVPGDTRDTSTPRALAKDLRAFVLGDVLGKGERA +QLTEWLRTNTTGDELIRAGVPKGWVVGDKTGSGSHGARNDIAVVWPPDSAPIVMAIMSNR +PDKDAAYDNKLIAEAASVVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Aquincola tertiaricarbonis TaxID=391953 RepID=UPI000614A914 +-------WAAIEAGVGGRLGVSVLDTGSGQVT-GHRLDERFPMCSTFKWLAAAHVLQRVD +AGLERLDRRIVYGPEVLIAHSPVTQRHADGSMTLAALCEATVTVSDNAAANLILQTLGGP +AGLTAFVRTLGDAHTRLDRTEPELNEATPGDPRDTTTPRAMAGALQRAVLGDALSPAGRQ +QLAAWLEAASTGFKRLRAAVPAGWRAGDKTGTGSRGTANDVAVFWPPAAPPLVVCAYLTD +SSAAPAQRDAALAEVGRQAVQ-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FBZ9_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDDMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AD3C6A +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8Q3_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASQQ +QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFAAEDF +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWKPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00110BCA4D +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIV----PNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=2 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2A8HEU7_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDALNEVIKFTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVLVK-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. CF142 TaxID=1144314 RepID=J2B1G2_9RHIZ +-dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +KGDESLDRRVTYGKEKLVTYSPETEKHAGGDMTMAEICKAGITLSDNTAGNLMLESFGGP +AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN +QLVDWMIANTTGGARLRAGLPSDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYMAE +TMVKMDEFNPVFAEIGKMITE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A221BPV1_BACCE +----DNSFAKLEKEYDAKLGIYALDTGTNQTV-SYRSDDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFALGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKTVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas axonopodis TaxID=53413 RepID=UPI000997F8E7 +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPNGAPMLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. Root1472 TaxID=1736470 RepID=A0A0Q7WIF7_9CAUL +-----RGMAALEARSGGRLGVAVLDTADGRTF-AYRGDERFAMCSTFKALVAGLVLKRVD +QGQERLDRRIVYGRNVLLAHSPATEKHVADGMTVGALCEATVTLSDNAAANILLYTFGGP +PALTAFLRGLGDKVTRLDGYEPNLNVVRPGELHDTTSPNAMLGALRALALGPVLSSASRQ +QLVAWLVANQTGDKRLRAGLPAGWKVGDKTGSWGDGTTNDIAVIWPPGRPPLLITAYLSR +STLADDGRNAVIAEVARLVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BED7BD8 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDHVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0011AA8223 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMVLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Ensifer sp. LCM 4579 TaxID=1848292 RepID=A0A1S1TJR0_9RHIZ +-dDVAKQLEELERQTGGRLGVSVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD +RGEEALDRPITFGRDVLLPHSPVTEKHVGGNMTVAALCEAAITISDNAAANLLLESFGGP +AGLTSWLRSIGDETTRLDRMEPELNEAAFGDPRDTTTPAAILETLGKLAFGSVLSESSRQ +QLVGWMVANKTGDARLRAGLPKDWRIGDKTGTSMTGAVSDIGFAWPDGRRPILVAAYTGE +AKAPLDILNPVFAEIGGIIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. FT13W TaxID=2654252 RepID=UPI001264777E +--TAQTQLAALEQAAGGRLGVAAWRHGSELRV-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLDQQVRYEKKELVTYSPITEKHLADGMTVAELCAATLQYSDNSAANFLMKILGGP +QAVTAYARSIGNTVFQLERWETELNSAIPGEVRDTASPTSMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATRIVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptoalloteichus hindustanus TaxID=2017 RepID=A0A1M5CIF5_STRHI +--AVHDELRELERQHGARLGVHATNTRTGATV-AYRAGERFPMCSTFKTLAAAAILRDLD +RDGEFLDRLIRYTEADIVENSVITAKRVATGMRIRELCWAAICHSDNTAGNLLLRQIGGP +AGVTRFCRSLGDPHTRLDRYEAELNTAIPGDPRDTTTPAAIGRDYRHLVLGDALNCQDRE +QLTAWLKANTTSSKRFRAALPPSWELGDKTGSGRYGTVNDVGVTWTPDGTPIVLAVLTTK +HEENATPDNELIVDTARLLA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A649UHG8_ECOLX +-------LAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTASARQLGDETFRLDRTEPTLNTAIPGDPGDTTPPRAMAQTLRNLTLGKALGDSKRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLAS--------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=I7AC74_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNXKAERIVVIYLRD +TPASMAERNQQI----------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C3E3J2_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGNALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0A7HF66_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDEHDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus muralis TaxID=264697 RepID=A0A1B3XTP4_9BACI +-----HDFAKLEEKFDAKLGIFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS +--IKDLDQRINYTSDDLVNYNPITEKHVDTGMTLKELSDASIRYSDNTAGNLILKQLGGP +AGFKKALKEMGDDVTNPERIEPDLNEVNPGETHDTSTPRALASSLQALTLGDALPKEKRE +MFIDWMKRNTTGDALIRAGVPKDWAVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR +DKKDAEYDDKLIAEATKEVMK-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas citri TaxID=346 RepID=UPI000541A728 +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRPDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG +AKVNDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VDM053 TaxID=1053249 RepID=R8PHP6_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGNALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1C4DAE5_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIAANLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8Q0_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAGLGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000E0F81C3 +--DIDKRLAALETRIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +KGDEKLDRRVTYGKDKLVTYSPETEKHAGGEMTMAEICKAGITLSDNTAGNLMLESFGGP +AGLTDWLRSVGDGTTRLDRMETALNEATKGDPRDTTTPDAMLDTLGNIALGSVLAEDSAN +QLVDWMMANTTGAARLRAGLPSGWKIGDKTGTGDNGSAGDIAIIWPPNRGPIVAAVYMAE +MTVKMDEFNPVFAEIGKMITE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF47705 +-----HSFAKLEKEYNAKLGIYALDTDTNKTV-AYHSDDRFAFASTSKSLAVGALLRTSS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SAFEKILREIGDTVTTSERFEPELNEVHPGETHDTSTPKAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2B4PFL3_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK +LLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=C2SKW4_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSNERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Virgibacillus necropolis TaxID=163877 RepID=A0A221MFF2_9BACI +----DEKFAQLENEFDARIGVYAIDTGTNQTV-KYHPDERFAYSSTFKVLAAAILLKQND +--IKDLEKVVTYTKDDLVTYSPVTEKHVDTGMTLLEISEAAIRKSDNTAGNLLLEALGGP +DKFKQALRNIGDDVTQPERYETELNEFTPGNKRDTSTPSTMAINLKKVALGDFLPNEKRE +LLIDWMKGNATGDALIRAGAPQGWKVADKSGAGSYGTRNDIAIVWPPNREPIVIAVMSRH +DKENAEYNDALVAKAAEITL--- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. 7K534 TaxID=2530366 RepID=A0A4R4MQT2_9ACTN +--EVAKQIRRLERTRDMRIGAYAVDTGTGRAV-GHRMDETFPFASTFKAIACGAVLRKAR +SDPGLLDRVIRYKESDLSAHSPITEKHVKTGMTVADLCHATITQSDNTAGNLVLKQIGGP +AGFTAFLRSLGDQVTRSDRWEPGLNEWRPGEKRDTTAPRAWAGTLQALTVGDALAPADRK +QLTAWMKATVTGDKRIRAGLPDGWTAGDKTGTGGYGSANDIAIAWPPSGPPVVMAIMTTK +QTPDAAADEQAIARTTTILL--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. NZIPFR-PS5 TaxID=1230465 RepID=A0A2G4DUT6_9PSED +--AIAQQLAELERRHGGRLGVAMLDTSSQRLI-SHRGDERFALCSTFKCLAAACVLARVD +QKHEDLSRRILYSAEQLVAYSPTTELHAGGQLSVGSLCEAAMTLSDNTAANLLLDSVGGP +EGLTAWLRSIGDTQTRLDRREPGLNENRPDDLRDTTTPVAMLQTLNTLVLGEKLTPASRD +QLTAWLVNNQTGDKKLRAGIPVSWRVGDKTGSGANNASNDVAVIWPGERGPMLVTAYYTG +SKASGDQINALMADIGRLAA--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009C4C313 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. VMFN-G11Ma TaxID=2135609 RepID=A0A2T5BJM3_9ACTN +------PLRELERRHDARLGVFAHNLRTRRTV-AHRADERFPMLSTFKTLAAAAVLRDLD +RHGEVLARRIHYTRADLVDGAPITGKNLAHGMTVAELCDAAIRYSDNSAGNFLLRLLGGP +TAITRFARSLGDRVTRLDRWEPELNSAEPGRRSDTTSPRAIGGSYARLVLGSALNAPDRA +RLTHWLLTNTTGDHRIRAGLPDSWTVGDKTGSGSYGTTNDVAVAWTDDGDPVVVAVLSTR +PQQDAAWDDALQAEAAAIVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00080F69D7 +----DDSFAKLEKEYDAKLGIYALDTGTNQTV-SYRSDDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFALGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKTVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000C83C3EA +---TNKKFVQLEKKFDVRLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGNKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF58360 +----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKEWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYNDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A5C4YKP3_BACCE +----DNSFAKLEKEYDARLGIYALDTGTNQTV-SYQSDDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKTVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cabrialesii TaxID=2487276 RepID=UPI0010117748 +----NHNFSKLEEEYDVKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEELNQRITYTRGDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILKQLGGP +AGFKKALEEMGDNVTNPERFEPDLNEVNPGETHDTSTAKALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR +DKKDADYNDKLIAEATKEVIK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2K8TT78_BACCE +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVGTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYENALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +GEKEASYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001374ADC5 +----HDSFAKLEKKYNAKLGIYALDTGTNQTV-AYHSNDRFAFASTSKSLATGALLHQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLRELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZHY1_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ +PH--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A7L210_BACCE +-qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYATRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] class A beta-lactamase n=1 Tax=Cronobacter sakazakii TaxID=28141 RepID=UPI000CFDD93D +-----------------RVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNSAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Stappia indica TaxID=538381 RepID=UPI0013033319 +--DIEGRLAALERKQGGRLGIAIHDVASGQTF-GNRADERFLMASTFKLMIAAFVLSRAD +REEEQLDRRIPFTTRDLVSWSPGTEKHAGGPLTVAELCEATMTMSDNTAANLLLKSFGGP +AALTAFARSLGDEITRHDRMEPELNADGPGDERDTTTPAAMAQTLRKLLFGDALSRRSRD +QLTAWLVTNRTGDARLRAGFPADWLVGDKTGTSGKGHANDIGVAWPSSRGALIVTAYCEM +PQAEAKVRDATMAEIARIAA--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFC90CF +--ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRTSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0013D33ED5 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNEWFAYASTYKVLAAAAVLKTSS +--NEKLNDIIRYTKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KSFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A168BD92_BACCE +----HDSFAKLEKKYNAKLGIYALDTGTNQTV-AYHSNDRFAFASTSKSLATGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLRELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8X1_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLPRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Sorangium cellulosum So0157-2 TaxID=1254432 RepID=S4XWZ0_SORCE +---AAPALARIEAQVGGRLGVAALDTATGARI-GHRAAERFAMCSTFKTLLAACILARVD +QGQLRLDHRVTYRASDLLDHAPVTRAHLAQGLTVEELCAAVVEISDNTAANLLLAQIGGP +AGLTAYLRGLGDPVTRLDRNELALNENVPGDPRDTSTPDAMTDTVRAILVGDALQRASRE +RLASWMVRSTTGFARLRAGLPKDWVIGDKTGTGI-GIANDVAVAWPPSRAPIVIACFVDA +PSASADARNAAHADVARVVAEAf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF9464B +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATNLQSFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD142 TaxID=718224 RepID=J7WUA1_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDRKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKLLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKNPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Caulobacter sp. 17J65-9 TaxID=2709382 RepID=A0A6B3UFS7_9CAUL +-----PRIAEIEARVGGRLGVAALDLQNGRRF-AHRGDELFPMCSTFKFLLASQVLARVD +RGEERLDRRVPVAASDIVSWSPATKERVGAHMSVEELCAAAVSQSDNAAANLMLGFSGGP +QALTAFARSLGDEVTRLDRTEPGLNMGRPGDPRDTTSPRAMLKSMGAIVLGPTLTETSRG +RLTGWMKATTTGGRRLRAGLPSAWTIGDKTGTGERGTANDIAVAWPPSGGPVLITAYLTG +AEADAKARDQALADVGRVVGETw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKF6_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMGTLKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTMRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Mutant KPC family beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A6B7HYH4_ENTCL +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Prauserella endophytica TaxID=1592324 RepID=UPI0010BE4B6C +--TAEREFGELEQRFDARLGVYAVDTGTGREI-SHRADARFAYCSTFKALATAALLSERT +--IAELDEVVPYTVDDLVTFSPVTEKHAGAGLPLRELMDAAVRYSDNTAGNLLLRELGGP +KGLQAALREVGDQTTHVDRFEPELNEATPGDIRDTSTPRALATTLRAYALGDALTADKRA +ILIDMLRRNLTGDELVRAGVPDGWVVGDKTGTGGYGTRNDIAVVWPPDRAPIVIAIMSSR +AEQEAEPDNALLAEATKTVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia mexicana TaxID=279262 RepID=A0A370H285_9NOCA +------HFTDLEAKHDARLGVFAVDTGTGRTV-ATREGERFPMASTFKGLACGAVLQAHP +LSSGYFDQVIHYPATDLVEYSPETEKHVDTGMTVAELCDAAITQSDNTAGNQILKLIGGP +AGFTAFLRSLGDTTSRLDRWETELNTAIPGDERDTTTPAALAADYRALVLGDALPAPERE +RLTSWLLANTTGGKRIRAGLPADWKVGDKTGSPAYGGALDVAIVWPPDRAPLVIAVLTAK +SEQHAQADNELVAAATREAV--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=B7IXB0_BACC2 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKCK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium bangladeshense TaxID=1138189 RepID=UPI0007E538A9 +-eNIERRLAALERRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGDEKLDRRVTYGRDKLVDYSPLSEKHADTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +PGLTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASSTGKERLRAGLPQDWKVGDKTGTGPNGSLGDVAVIWPPDRGPIVAAVYIAE +ATAPVKDLNTIFAEVSKMITE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FC11_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSHVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=2 Tax=Cohaesibacter gelatinilyticus TaxID=372072 RepID=A0A285PBP1_9RHIZ +-qELNRTISSWEKHLNARIGVLLSEMESDWSI-AHRADERFPMSSTFKSLLCGAVLARVD +ANEENLSNKITFTRKDLVSYSPVTKKRVKDGMSVSELCEATITISDNTAANLLLKRIDGP +KGLTKFLRKMGDTTTRLDRWETELNEGKPGDARDTTTPRAILGSLEKLAFGNVLKQKSSR +QLRQWMIDDKVADALIRAHLPKGWTIGDKTGAGGYGTRGIIAFIEKPDGKRYLAAIYMTE +NKADFPMRNKVISDIGRAMIT-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus TaxID=1386 RepID=UPI0009ACEFA2 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTIADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAAYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Virgibacillus halodenitrificans TaxID=1482 RepID=A0A1J0GZT9_VIRHA +----DEKFAEIEKEYNARLGVYAINTGTNQRV-QYNSDDRFAYASTFKVLAAAILLKQNS +--IEDLEKVVTFSKDDLVSYSPVTEKHVDTGMTLGEISEAAIRHSDNTAANLLLEEIGGP +KQFKQALRDLGDSVTQPMRFETELNEFTPGKKHDTSTPKAMAKTLKKVALDDFLPEDKRE +LLHNWMKGNATGDKLIRAGAPAEWVVGDKSGAGSYGTRNDIAIVWPPDREPIVIAVMSRH +EEEDAEYDDALIAKAAEIALN-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. BK418 TaxID=2512120 RepID=A0A4R3GR92_9RHIZ +-dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +RGDEKLDRRVTYGKEKLVTYSPETEKHAGGEMTMAEICKAGITLSDNTAGNLMLESFGGP +AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSVLAEDSAN +QLVDWMVANTTGGGRLRAGLPSDWKIGDKTGTGDNGSAGDIAIIWPPNRGPIVATVYMAE +TTVKMDEFNPVFAEIGKMITE-- +>[subseq from] class A beta-lactamase n=1 Tax=Labrenzia aggregata TaxID=187304 RepID=UPI000986F0EB +---LEKTVTSAESRLSARIGVAVLDTETGKTW-THRADERFPLNSTFKAFLCAALLEKGE +QGEVQPERRVRIRSQDLVSYSPVTEKKVGSGMTYLELCEAAVAISDNAAANLVLEAVGGP +AGLTDYLRGIGDTITRLDRTEPGLNEGRPGDARDTTTPAAAVATLQKLVLGDALSSTARV +QLTGWLLDNKVGNATLRAGLPEEWPVADKTGAGANGSRNNIGVIWPDDREPVVIAVYITQ +TDASFDDRNKAIADIAAALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8XBR4_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDVKYDDKLIADATKIVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0009950312 +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSSPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 166amftsu TaxID=1761753 RepID=A0A1H3QIR1_9BACI +--ATHQKYAQLEKKFDARLGIYAIDTGTNRTV-SYKQNERFAFASTYKALAAGALLMQNP +--IDKLNEVITYTKDDLVEYSPITEKYVDTGMTLGEIAEAAVRYSDNTAGNLLFKELGGP +EGFETALKQIGDRVTQADRFETDLNEAIPGDIRDTSTAKALANDLKAFTVGNALPADKRK +ILTDWMHGNATGDKLIRAGVPKDWEVADKSGAGSYGTRNDIAIVWPPNREPIIIAILSSR +DTKDATYDNELIAQAATITIN-- +>[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=A0A4R7RDF3_9BURK +----EAQLATLEQSSGGRLGVFALNTADGKQT-GYRADERFPFCSTFKVILIGAILARST +QVSGLLQQRIQYSQSDVVHYSAVTAQHVGDGMTVGELCVAAIQHSDNTAANLLIKLLGGP +QAVTAYARLTGNPVFRLDRMETSLNDAVPGDPRDTATPAAMARSLQTLTLGEALPVPQRT +QLLDWLRGNQMGSKRIGAALPAGWSMGDKTGTGDYGTANDLALIWPPSRPPILLAIYQTQ +REQDAKARDDVIAAAARIVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000A370BA1 +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKNSLIEIGDTVTNPERFEPELNEVHPGEIHDTSTPKALATSLQAFALGDILSTEKRN +LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A0G8BZK7_9BACI +--AMYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Ensifer alkalisoli TaxID=1752398 RepID=A0A5P6NJW4_9RHIZ +-dDVAKQLEELEKRTGGRLGVSVLDTRTNISF-GHRETERFAMCSTFKALAAACALARID +RGEEALDRRIAFGRDVLLPHSPVTGKHVGGNMTVAALCEAAITISDNAAANLLLESFGGP +AGLTSWLRSIGDEATRLDRMEPELNEAAFGDPRDTTTPAAMLETLRKLAFGSVLSESSRQ +RLVGWMVANKTGGARLRAGLPRDWRIGDKTGTSMAGAVSDIGFAWPDGRGPILVAVYTGE +AKAPLDALNPVFAEIGRIIA--- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. T12-10 TaxID=2024610 RepID=A0A5A7W5T4_9BURK +-kAIEAELASIERSVDGRLGVALLDMETGMRA-GHRVGERFPICSTFKQMLAANVLARVD +RGEENLERRIVFGQDRIDQYAPVTRERTGAPMTIAELCDAIVTMSDNTAANLLLDTVGGP +AGFTAFMRRLGDTVTRLDRNEPSLNEAIPGDPRDTTTPIAMLNDLREVLLGDALTAASRA +RLLAWGVGNRTGDTRLRVGVPGNWRVADKTGTGERGTTNDVGLLWPQDRQPIVVTVYLTQ +SPAPLRAREAAVADVARAIVR-- +>[subseq from] Ampicillin resistance protein n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00025EFB0D +---------------GARVGYIELDLNSGKVLeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLSGELLTLASRQ +QLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGEHGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASL---- +>[subseq from] Beta-lactamase n=1 Tax=Herminiimonas arsenicoxydans TaxID=204773 RepID=A4G2R9_HERAR +--AIQQEFSRLEASARGRLGLSAFNTGNGMRV-QYRAYERFPVCSTFKTIVAAAILQKST +TDKRLLNKRIRYNKDEVEQYAPITQKHIADGMSIAELCAATLQYSDNAAANFLMQELGGP +AAVTAYARTIGDDTFRLDRWEPELNTAIPGDLRDTSTPAAMGKSVQRLTLGDALALPQRE +QLVNWLKGNTTGGKRMQAGVPQDWIVGDKTGTGYYGTTNDAGVIWPATGAPIVAAIYFTQ +NEKEARPRDDIIASATRIVVA-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009ADB12E +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGGYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis lactamdurans TaxID=1913 RepID=BLAC_AMYLA +--AVEQEFTRLQTQYDARLGLYAVDTGSGESV-AFRADERFAFASTFKALAAAAVLDSTT +--PQQLDQVVRYSKDELLENSPITKDHVATGMTLRELCDAAVRFSDNTAGNLLLKHVGGP +QGLDAALTAVGDEVTSADRWEPELNSAVPGDVRDTSTPRALAHDLRQFVLGDALAEDDRA +LLTDWLRRNTTGGTVIRAGVPADWVVGDKTGSGYYGGRNDIAVLWPPNRAPIVMAVMTSR +EEPRAKRADALLADAARVAVT-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1B2VWF2_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNXERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIA---------- +>[subseq from] UPI001411B27B UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI001411B27B +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRTPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=R8D6P3_BACCE +----NHSFVKLEKEYDAKLGIYALNTGTNQTV-TYRSDERFAYASTHKALAVGALLQKNS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Class A beta-lactamase KPC-40 n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=A0A4Y6E759_9ENTR +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGSANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodobiaceae bacterium TaxID=2026785 RepID=A0A2Z4UK77_9RHIZ +---ILETVRTVESRLGGRVGISIHDTGSGQRW-EHRSDERFPMSSTFKAFACAAVLSRIE +GGAERLHRVIEIEEEDLVTYSPVTETRVNTVMTIAELCEATITLSDNTAGNLILKSIGGP +KAFTDYMRSIGDETTRLDRWETDLNEGKPGDRRDTTTPRAATTSLGRLLLGPTLSESSRE +QLTTWMENDKVADALLRSVLPVGWRIADKTGAGGHGARSIIAVIWPPAESPILISIYMAE +SDASFAERNEAIAEIGAAIVT-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Kluyvera georgiana TaxID=73098 RepID=A0A3S7Q8I3_9ENTR +---VQQKLAALEKSSGGRLGVALIDTADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKKVLSQKVEIKSSDLINYNPISEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARAIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRHLTLGSALGETQRA +QLVAWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ +PEQKA------------------ +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI0009B1E29E +----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDPRDTSTPKALATSLQDYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520H5S5_9BURK +--STHRALQRIEAASGARLGVALLDTATGRRV-AHRADERFPMCSTFKFLAAALVLQRVG +RGLESLDRPVAIDAAKLVTYSPATGRQVGGHMTMGALCEAAVTLSDNTAANLMLESFGGP +AGLTRFARTLGDDVTRLDRFETALNEAIPGDPRDTTSPAAMLGLMRELLLGRALAPASRE +QLRGWMRGNTTGATSLKAGLPADWPIGDKTGAGGHGTRNDIAIVWPRDGAPVLVAAYLTG +AALDDAAQRRVLAEVGALL---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus siamensis TaxID=659243 RepID=UPI000E31AFA5 +---TNKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNDIIRYTKDDLVTYSPITEKHLDTGMRLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNVLISEAAKAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00125F5478 +----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHMDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYNDKLIADATKVVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8T0_9BACT +-----------EDQLGARVGYIELDPNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0011452F15 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8V5_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGSDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium frigidaeris TaxID=2038277 RepID=A0A2G8MF47_9RHIZ +--DAAARLAQLERRDGGMLGVEVRDTATGRRF-GHRADERFPLCSTFKAIAAAAVLARAD +TGEDDLSRRIAYGHDALLSYAPVTSKHVETGMTLAELCAAAVVWSDNTAANLMLDTIGGP +EGITAFARAHGDTVTRLDRTEPTLNTAIPGDVRDTTSPAAMVGLLDNVLLGRALSAESRA +RLVGWMHDSPTGLKRVRAGLPAGWRTADKTGTGDNGTANVVALIHRPDGAPILSAVYLTG +SPAEPAARDALHAEIGRLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium bangladeshense TaxID=1138189 RepID=UPI0007E5B7E8 +--NIERRLAALERRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGDEKLDRRVTYGRDKLVDYSPLSEKHADTDMTIAELCEAAVTVSDNTAGNLLLESFGGP +PALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD +RLIAWLVASSTGKERLRAGLPQDWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVKDLNPIFAEVSKMITE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE32C07 +--DIDKRLAALETRIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +KGDEKLDRRVTYGKDKLVTYSPETEKHAGGEMTMAEICKAGITLSDNTAGNLMLESFGGP +AGLTDWLRSVGDGTTRLDRMETALNEATKGDPRDTTTPDAMLDTLGNIALGSILAEDSAN +QLVDWMVANTTGGARLRAGLPTGWKIGDKTGTGDNGSAGDIAIIWPPNRGPIVAAVYMAE +MTVKMDEFNPVFAEIGKMITE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. WP9 TaxID=1500263 RepID=A0A1H5NEI0_9BURK +--AIRRRLAEIEAASGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKVLAAGAVLARTD +RGAEDLQRRVVFSHSDVVPNSPATSKHTRELMSIAELCKAAITLSDNTAANLLLATFGGP +AGLTAFARGLGDGITRLDRNEPTLNEAIPGDPRDTTTPNAMLGNLRELLLGEHLSSSSRA +QLLAWLAANETGGARLRARLPKEWGVGDKTGTGDHGSANDIAILWPPGRGPVLVTVYLTE +TDGSAARSNAAIADVGALVA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium pisi TaxID=574561 RepID=A0A427MYG9_9RHIZ +-dDIQRRLAALEKRTGGRLGVSVLDTQTSISF-NYRGSEAFPMCSTFKALAVGFVLARVD +KGEENLQRRVSYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAANLLLESFGGP +PVLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSILTEASCD +RLIAWLVASTTGKERLRAGLPQDWKIGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIGE +ATVPVKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI000E1E90E6 +--ELRDEWARIERRSGGRLGIGLLDSATGKRI-GQREDERFPMCSTFKFVLAAAVLQRVD +KGELTLAQRVKIRASDMLSHAPVTERHVGRSLSVGELCWATMIYSDNPAANLLFPLVGEP +AGLTAFLRGIGDTHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGDALQPASRE +QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAGRDAALKAVAAAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. 344 TaxID=1566280 RepID=A0A1I0YXH3_9BURK +---AHTQLAALEQAAGGRLGVAAWRQGVEQRV-AYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMRVADLCAATLQYSDNSAANFLMKILGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLVIAVYYTR +EQKNADTNQDIITAATRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces atroolivaceus TaxID=66869 RepID=UPI000690B3AF +--RTERAFAELERKYDARLGVYALDTGSGRTV-THRPDERFAYASTCKALLAGAVLDRNS +--LRELDRLVRYGRDDLVSHSPVTERHVATGMSLRELCDATVRYSDNAAANLLFRELGGP +RGLQDALRGLGDDVTRCDRYEVALSDAVPGDLRDTSTPRALADDLRAYVLGTTLPTDKRA +VLTDWLKRNTTGDHTIRAGTPDGWQVGDKTGTGGYGTRNDIAIVWPPDRAPIALAVLSRR +DTKDAERDDALLARAAEVTFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas phaseoli TaxID=1985254 RepID=UPI000536ACE3 +--MLRAQWAQIEHGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLATYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00115589AB +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSKERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDPVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEARYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Alloactinosynnema album TaxID=504798 RepID=A0A1H0UTL2_9PSEU +--SAQRTLRELEAEYPGRIGVTAINTGTGKTI-RYRAHERFALCSTFKCLASAAILQEAR +ADPGLMERVIHYTHADLVTHSPVTELHVDTGMTVRALCAATMTTSDNTAANLLLRLLGGP +SSIGEFARTLGDRWTRLDRYETDLNTNLPGDPRDTSTPDAIARDLRKLVLGDALHPSDRA +ELTGWLIGNKTGDERIRAGLPKDWTTGDKTGGGDYGALNDIAVTWPPGGAPLVIAVYTTR +TDPTIPGQNRIVADIARVVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas citri TaxID=346 RepID=UPI000B5C8AA1 +--MLRARWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD +QGKLTLARQVKIHASDMLEHAPVTERHVGGSLSIGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGGPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. AR2-1 TaxID=2217816 RepID=UPI0011ED4D23 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTPEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A657Z4T2_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTPEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI001155C32B +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPTRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000FFF01A4 +------PLRELERRHDARLGVFAHNLRTRRTV-AHRADERFPMLSTFKTLAAAAVLRDLD +RHGEVLARRIHYTRADLVDGAPITGKNLAHGMTVAELCDAAIRYSDNSAGNFLLRLLGGP +TAITRFARSLGDRVTRLDRWEPELNSAEPGRRSDTTSPRAIGGSYARLVLGSALNAPDRA +RLTHWLLTNTTGDHRIRAGLPASWTVGDKTGSGSYGSTNDVAVAWTDDGDPVVVAVLSTR +PQQDAAWDDALQAEAAAIVAE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T9G2_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAATLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDVRNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. Soil768D1 TaxID=1736405 RepID=A0A0Q9VIG4_9BACI +----NHDFAKLEEKFDAKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNQRITYTREDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP +TGFKKALEEIGDNVTNPERFEPDLNEVNPGETHDTSTPRALATSLQAFTLGDTLPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWXVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DKKDADYNDKLIAEATEEVIK-- +>[subseq from] OFF7_DB04V3 n=1 Tax=synthetic construct TaxID=32630 RepID=UPI00077DEF8E +----------VAARLKARVGYIELDLNSGKILeSVRSEERFPMMSTFKVLLAGAILSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELASAAITMSDNTAANLLLTTIGGP +KGLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTPASRQ +QLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIVAALGPDGKPSRIVVIYTTG +SQATMDILNEAIAMLGRAMIEKw +>[subseq from] class A beta-lactamase n=1 Tax=Numidum massiliense TaxID=1522315 RepID=UPI0006D5B046 +------DFAKLEEQFDARLGVFALDTGTNQTV-TYRADERFAHVSTHKALTVGVLLQKKS +--IEDLNQTITYTRDDLVDYNPITEKHLDTGMTLKELCDASIRYSDNTAHNLILKELGGP +KGLKKSLREIGDEITNPERFEPELNEVNPGETRDTSTPRALATSLQAFTIGDVLPTEKRA +LLTDWLKRNTTGDTLIRAGVPKGWKVADKTGAGFYGTRNDIAIIWPPDKDPIVLAVLSSR +DKKDADYNDKLIAQATKKVID-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A2T8L6_KLEPN +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +LLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAAL---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B8YMA8_BACCE +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNATGDKLIRAGVPNDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis subsp. higo TaxID=132266 RepID=A0A243KGJ8_BACUH +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKITLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas wittichii TaxID=160791 RepID=UPI00055B36D8 +--DISKQLGDLERQSGGRLGVAMLDCGNGRLI-GWRLDDRFPMCSTFKMMLAAFILHRVA +IGEERLDRRIVVGTADLLSYAPVTGKHVGDPMTIEALCEAAVAMSDNTAANVLLATAGGP +MAFTRFARSIGDRETRLDRIEPALNEARAGDPRDTTTPAAMARSLRKIALGSALPADGRT +LLTRWLIGCRTGAARLRAGLPAGWAVGDKTGTGERGSTNDIAIIWPTGRDPVIVAAYMTG +GTLGADAREAILASVGRLAAGYf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF3CB6C +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPEDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID13726 TaxID=2706058 RepID=A0A6B2XAB9_9ACTN +--DVPARLRALEKDHDARLGVYAHNLATGRSV-AHRADELFPICSVFKTLTAAAVLRDLD +RDGEELARRIHYTRADLVDGAPVTGKNLAHGMTVAELCDAAIRYSDNSAANFLLRELGGP +TAITRFARSIGDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGRSYGRLVLGDALNRRDRA +RLTDWLLRNTTGDRRVRAGVPVGWTVGDKTGSGSYGTTNDVAVAWTPEGAPIVLAVLSTT +PQADRAWDDALVAGAASVAA--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AEC803 +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNATGDKLIRAGVPNDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SWL9_9BACT +--DAEARLAELERAHGGRLGVAVLDLANGRRI-GHRADERFLMLSTFKTLAAALVLARVD +RGEERLDRRIVFSESDLVVWSPVTENRVGRAMTLAELCEATITLSDNTAGNLLLDSFGGP +AALTDYLRSLGDEVTRLDRIEPDLNEDAPGDLRDTTTPAAMLETLHKLLFGDALSRHSRD +QLNAWLTINKTGDQRLRAGFPENWLVGEKTGTNRSGTANDAGVAWPIDRGPILVAAYCEM +SSISPEKRNAVLAEVGRIAA--- +>[subseq from] Beta-lactamase n=5 Tax=Bacillus TaxID=1386 RepID=A0A2B1CB74_BACTU +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKATATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] D12_DB04V3 n=1 Tax=synthetic construct TaxID=32630 RepID=UPI00077DEFCA +----------VAARLKARVGYIELDLNSGKILeSVRSEERFPMMSTFKVLLAGAILSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELASAAITMSDNTAANLLLTTIGGP +KGLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTPASRQ +QLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIVAALGPDGKPSRIVVIYTTG +SQATMDILNEAIAMLGRAMIEKw +>[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus halodenitrificans TaxID=1482 RepID=UPI000EF445C1 +----DEKFAEIEKEFNARLGVYAIDTGTNQRL-QYNPDDRFAYASTFKVLASAILLKQNS +--IEDLERVVTFSKDDLVTYSPVTEKHVDTGMTLGEISEAAIRYSDNTAANLLLEELGGP +EQFKQALRDLGDDVTQPERFETELNDFAPGKKRDTSTPKAMANTLKKVALDDFLPDDKRE +LLHNWMKGNATGDKLIRAGAPEEWVVGDKSGAGSYGTRNDIAIVWPPDREPIVIAVMSRH +EEEDAEYDDALIAKAAEITL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFC9D90 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPEDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus firmus TaxID=1399 RepID=A0A0J5W1J3_BACFI +--NTNQKFKQLEKEFDARLGVYAYDTGTKKTI-AYRSNERFAYASTFKPLAAAILLKRKS +--LEEMDEIITYTSDDLVTYSPVTEKHVKTGMTLRELCEAAIRHSDNTAGNLILEELGGP +DGFEAALKEMGDTVTKPERFETDLNEAEPGDIRDTSTPKALAASLQKVLMGDFLPEEKRN +VLTDWMRGNVTGDPLIRAGVPSGWEVADKSGAAGYGTRNDIAIVWPPNREPIIMTILSSR +DSKDAEYDNSLIAKTAEMTIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000C161908 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKV----- +>[subseq from] Beta-lactamase n=1 Tax=Saccharomonospora azurea SZMC 14600 TaxID=1114959 RepID=H0K2N4_9PSEU +---VQGELRALEARHAARLGVYGINTRSGAVV-SYRAHERFPMCSTFKTLAAAAVLRDLD +RDGEVLDSWVHYTEDDLVVGSPVTERHVGTGMRVADLCAAAVSESDNTAANLLLDRIGGP +RGVTRFCRSLGDRLTRLDRYEPDLNSALPGDLRDTTTPAAIAEDYRRLVVGTALDRGDRA +RLTTWLTESVTSDTRFRAGLPSHWRVADKTGSGSYGTANDVGVAWTDDGTPLVLAVLSTK +HTPDAEWDDALVAGTARVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000A19DFD8 +----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQQKS +--IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQDYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Prauserella coralliicola TaxID=1401264 RepID=UPI000D830348 +--TAEREFGELEQRFDARLGVYAVDTGTGREI-SHRADARFAYCSTFKALATAALLSERT +--IAELDEVVPYTVDDLVTFSPVTEKHAGPGLPLRELMDAAVRYSDNTAGNLLLRELGGP +KGLQAALREVGDHTTHVDRFEPELNEATPGDIRDTSTPRALATTLRAYALGDALTADKRA +ILIDMLRRNLTGDELVRAGVPDGWVVGDKTGTGGYGTRNDIAVVWPPDRAPIVIAIMSSR +AEQEAEPDNALLAEATKTVVE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B2A106 +-qATYKDFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CB02058 TaxID=1703921 RepID=UPI00093C69F5 +---TKASFDELEQKFDARLGVYAIDTGSGLSV-THRPDERFAYASTCKALLAGAVLDAVT +--VARLDRRVRYGRDELVANSPVTGKHVDAGMTLRELCDAAIRHSDNTAANLLFHELGGP +RGLQDALRGLGDRTTRCDRYETELSEAAPGDPRDTSTPRALAAGLRAYALGNVLGAKERA +LLTDWLRRNTTGDDVIRAGTPDGWVVGDKTGTGGYGTRNDIAVLWPPDSEPVVLAVLTRR +ETRDAVHQDALIAEAARVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI000E1F3D95 +--ELREEWARIERRSGGRLGIGLLDSATGKRI-GQREDERFPMCSTFKFVLAAAVLQRVD +KGELTLAHRVKIRASDMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLIGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMASTLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAGRDAALKAVAAAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. NAS80.1 TaxID=1680159 RepID=A0A1Q5RNH8_9BRAD +-----EAITQLELKSGGRLGVSVLDTRTGAQI-HHKGNERFPMCSTFKVLASAAILKNAG +SKLDSLERRVRIEQADIVENSPVTLEHVGGEMSLLEVCDAAITRSDNTAGNLLLKNIGGT +AGLTSFARSIGDKVTRLDRTEPELNEATPGDPRDTTTPNAMTASFSGLLLGRVLLPEARD +QLAKWLIANKTGDTRLRAGLPQSWRVGDKTGAGEHGTTNDVAIVWPPEHPPLIIGVYLTG +AALDPNGRNDVIASVGREISKSf +>[subseq from] Beta-lactamase class A n=1 Tax=Paenibacillus sp. cl141a TaxID=1761877 RepID=A0A1H7QMD1_9BACL +-----------AAEDGIELSVGIQDLSGGGKI-QVGSSDVYYAASTIKIAIVTALMQDIE +AGKYALEQTIQVQPEQVVGGAGSLKDKFPLDITIESLARLMITQSDNTATNALIDLL-GF +ERINAFIEEQGFETMQLGRKMMTPAKS--PAADNYVDGEELLTLLERIYAGEILTAKSRD +QILAWMKAQEV-KTKFGAALP-GKPIAHKTGELGD-VSHDIGYFLVPGRE-AAVTVLTKV +TKKAQELGNPVVQRVAKAVYN-- +>[subseq from] Beta-lactamase class A n=1 Tax=Paenibacillus sp. cl141a TaxID=1761877 RepID=A0A1H7QMD1_9BACL +------------EDKGIRVSVGLKDLSGDREL-LLGSRQSYMPASTIKMALVSGLMKEVD +AGKLTLEETVKVEKEDVVGGTGSLQKETPQDVTIERLAKLMITQSDNTATNVLIDVV-GL +DEVQNLMDELGLDVMHLGRKMFAAA--PTPEQDNYIDAEDLVHLLAYIHSGSFLSDNSRD +QIIDWMKAQEV-DTKFGAALP-DAPIAHKTGENAN-VTHDAGYFLVPGRE-IAISVLTEV +TTEAQAIGNPVVQEIAKAVYE-- +>[subseq from] Beta-lactamase n=1 Tax=Methylarcula marina TaxID=72022 RepID=A0A422QXU4_9RHOB +--AVTDRVIEAEQKLRARVGYSMLDLTSGETA-GYRSDERFPMLSTFKVPLCAAVLARVD +AGEEDLDRRITYSSADLVEYSPVTEQHVESGMTLSDLCEAAITMSDNTAANLLLESVGGP +EGLTAFLRATGDGISRLDRWETELNEALPDDPRDTTTPQAMVATLDRLLFGGILSESARK +TLVTWMENNLVADDLIRASLPQGWYIADKSGAGARGSRAITGVLGPEGRPERIVAIYMTE +TPASIETRNAEIAAIAKVIVADw +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. WMMA1423 TaxID=2591108 RepID=UPI00114625DE +--KVTRQIGRLEATHHARIGAFAIDTGTGRTV-SHRPDERFAFASTFKAMACGAVLRKAR +QDPGLLDRVIHYTEDDLVDYSPVTEKHVDTGMTVADLCHAAITQSDNTAGNLVLRQIGGP +AGLTAFFRSLGDRVSRSDRWETDLNIWAPGEVRDTTAPRPWAGDLRALTTGGALVPADRK +RLVDWMKATVTGDKRIRAGLPKNWTVGDKTGTGGYGTANDIAIAWPPSGAPLVIVITTNG +LSADAEADDKAVAQTARILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF4C2EF +----NDSFAKLEKEYDAKLGIYALDTGTNQTF-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDEKITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTALNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPKEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2C5GQ78_9BACI +hqATYKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Micromonospora sp. KC213 TaxID=2530378 RepID=A0A4R4Q158_9ACTN +---------ALEQRFDATLGVYAIDTGTGRTL-AHRPDERFAYASTVKALAAGALLDVTS +--DAELDRVVRYRRADLVTYSPITEQHVDSGMTLRAVADAAVRYSDNTAANLIFAELGGP +DGFERRLREIGDTVTEPARIETALNEAAPGDVRDTSTPRAMATSLRAYALGDALSDADRA +VLVDWLRRNTTGAKLIRAGVPADWQVGDKTGSGGYGTRNDIAVLWPPQGAPIVLAVLSRR +DTKDAGYDDALIAEAARLVV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SRB_331 TaxID=1969379 RepID=A0A328MBV8_9BACI +-----DSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYNREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFALGDILLTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium lusitanum TaxID=293958 RepID=UPI0013DA0B9B +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GNREEERFPLCSTYKALAVGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHADTDMTVAELCGAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDTIGLLTLGNTLSETSRD +QLINWLVGNTTGNNRLRAGLPTEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATASAKDVEAVFAEVGKIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. B05 TaxID=1945859 RepID=A0A1V3PR98_9GAMM +----EARLAALQRRHGGRLGVAVLDTGTGRRV-AQRGDERFLLCSTFKVLAVAAVLARVD +AGGEKLDRRIVFGRDVLLDYAPVTRQQVGAPMTVAGLCAAAITLSDNTAANLLLASLGGP +AAVTRFVRSLGDPVTRLDRIEPELNEGGPGEIRDTTTPNAMLDTLQRLLLGHVLTEASRT +RLIGWLRACTTGTDKLRAGIPADWQAGDKTGSGAHGESNDVAIFWPPHRKPILVTAYYAG +SSADGQQRGAVLAEVGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. Root483D2 TaxID=1736545 RepID=A0A0Q7NCQ8_9RHIZ +-kDIEKQLAALEKQTGGRLGVYVLDTKTKASF-SHRPDERFAMCSTFKALAAACVLARAD +KGEEKLDRKVLITKKHLLTYSPAVEKRVGGAMTVRELCDAAVTLSDNGAANLLLASFGGP +KGLTDWLRTIGDATTRLDRWEPELNEAKIGDPRDTTTPKAMTETLGKLLLGDTLSTASRD +QFTAWLIANTTGAKRLRAGLPKTWTIGEKTGTSGHGEAGDIGFVRPSGDHTILVSVYIAE +GKKPTKELEPVFGDVGKLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Haematospirillum jordaniae TaxID=1549855 RepID=A0A143DG37_9PROT +---AVQRLSDLESTFDGRLGVFAFDTSSGAAL-AWRSEERFPLCSTFKAFLAAAILHRST +SDIGLLDRVISYPLEELVFHSPVAQQHVHSGMSVRDMCAAAIQYSDNTAANLLMRILGGP +DAVTAFMRQTGDMDFRLDRWETDLNTAIPGDLRDTSTPVAMARSLDHLLFGDVLSDTHRA +LLQDWLKGNTTGASRIRAGVPDGWMVGDKTGSGSYGTANAIGVLWPPGRKPVIVSVYTTQ +HYRGAVWRNDIVAQATRIIVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Microtetraspora fusca TaxID=1997 RepID=UPI0008316487 +------RFAALERRHGARLGVYALDTGTGITV-AYRADERFAFCSTFKALAAAAVLHRNP +--LSHLDTRVTYTEADVNSISPITRNHIATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP +RKLTAYLRELGDTVSRMDNYEPELNSDRPKDPRDTTTPRAIASDYQKLVLGDALTPDKRA +LLKDWLVRNTTGGERIRAGLPKGWKVADKTGTGNYGRVNDIAVVWPPHAASLVLAVMSDR +RGFNAPQESALIAEAARQAV--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2B3KNB9_BACTU +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKITLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0008727F4A +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEAHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2C2AN01_BACTU +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPKLNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00053502D5 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNTTGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C2FBI8_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNTTGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces vinaceus TaxID=1960 RepID=UPI000A3736DE +------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP +--GARLDGRITYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAANLLLRDIGGP +RGVTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALILGDALPAAGRA +LLTDWLVRNKTGDRRIRAGAPRGWKVGDKTGSGDWGRCNDVAVLWPGGGPPLMLSVLTER +PDRAASPSDELVAEAARRVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00125EDB68 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Sinorhizobium americanum TaxID=194963 RepID=A0A1L3LJV3_9RHIZ +--DVTKLLAELEKRTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACVLARVD +RGEEKLDRRITFGKDVLLPHSPVAEKHVGGDMTVAELCDAAVTISDNAAANLLLESFGGP +AGLTSWLRSIGDRTTRLDRTEPDLNEAKFGDPRDTTTPVAMLETIGKLAFGSVLAESSRR +QLVEWMVANTTGDARLRAGLPKEWQIGDKTGTSSTGAVSDIGFAVPKGRGPILITVYTGE +AKVEPAELNPVFAEVGKIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A109G0V0_BACMY +-----HSFVKLEKEYDAKIGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIMLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD4FA22 +-dDVDQQLAALEKRTGGRLGVSVMDTGTNVSF-SNRETERFPLLSTFKVLAAGMVLARVD +GGDENLERRVTYDQDKLVTYSPETEKHVGAEMTVGELCKAAITLSDNTAGNLLLDSLGGP +EALTKWLRSIGDTLSRLDRIETELNEAKKDDPRDTTTPDAMLDTLGNLALGTVLSEPSRQ +QLIDWMIANTTGAARLRTGLPEEWKVGDKTGTGSNGSAADIAIIWPEESSPILVAVYVAE +ATAPVSELNDVFAEVAKLAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. ISID311 TaxID=2601673 RepID=A0A5C6WBN8_9ACTN +--DAHAALRRLERAHRARVGAYAHNTATGTTI-AYRADTRVPLCSVFKTLAVGAVLRDLD +HNGETLARRVHYTAADVVANSPVTGKHLATGMTIAELCAAALQRSDNTAANLLLRTLGGP +TAVTAFARSLGDRTTRLDRWEPDLNSAEPWRTTDTTTPAAIARTYTRLLLGDALTPADRA +RLTAWMKANETNTDRFRAALPRDWTLADKTGTGSYGTGNDVGVAWTPDGTPLVLAVLTGT +AQQAAPSDDPLVADVTRVIAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 4F TaxID=1751294 RepID=UPI00073A9AF6 +------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDRRP +--GARLDERISYGAADLVPYSPVTEKHTGQGMTLRELCDAAVRYSDNTAGNLLLRDIGGP +RGLTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVHGDALPAAGRA +LLTDWLVRNTTGDDRIRAGVPRGWKVGDKTGTAEWGRANDVAVLWPGGGSPLVLSVLTDR +PDRAAPGQDELVAEATRRVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillaceae TaxID=186817 RepID=C2UE15_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEASVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A9A0N8_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYENALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFMVGDALPAQKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI0011559997 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDIVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK +LLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas axonopodis TaxID=53413 RepID=UPI000996316A +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLATYLNG +AKVDDAARDTALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus siamensis TaxID=659243 RepID=UPI0012E0C15A +---TNKKFVQLEKKFDAKLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS +--NEKLNDIIRYTKDDLVTYSPITEKHLDTGMRLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALISEAAKAALD-- +>[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI00039AE61E +-tEMKDDFAKLEEQFDAKLGIFALDTGTNQTV-AYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVMK-- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5SMI5_9BACT +--EFENRVATIEARTGGRIGVAALDTASSKHL-DCRSEERFPMCSTFKFLAAAAVLKRVD +EKQEKLDRFVPYDAKDILEYAPVTKIHLKEGMTLGALCAAAIEQSDNTAGNLLLDAIGGP +IGLTNFARTIGDKVTRLDRKEPELNSAIADDERDTTTPAAMLADMLQLLLGNTLSPSSRH +QLEQWLQANQTGASMIRAGVPTSWIIGDKTGRGANGATNDIAIMRPPGRAPILLVIYSAG +STATANDRAAAIVEAARVVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A4Q9ZFM8_BACMY +----NQSFVKLEKNYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKQN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +VKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0011460A66 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2B5AKN3_9BACI +----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLEQRIKYTSKDLVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEAQPGDTRDTSTPKALATSLQDYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. RZ2MS9 TaxID=1806216 RepID=A0A1G1UFZ5_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIVTNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2T0EC12_9BACI +----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIENRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus cereus group TaxID=86661 RepID=A0A221BSW3_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LETLDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF515C3 +----NQALAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9PJG7_BACCE +----NQALAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] CRH family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Chromobacterium sp. C-61 TaxID=238241 RepID=UPI0009FD351E +----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPLCSSFKGFLAAGVLAQSQ +EKPGLLDKRIRYSKTALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLKEINGP +AALTAFMRSIGDASFRLDRREPELNSAIPGDPRDTSTPKAVAESAQKLALGKALPEPQRQ +QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH +AKKEAKHSDEVIAAAARAALGAf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1X6PRF9_BACMY +-nTVNQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYNDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella quasipneumoniae subsp. similipneumoniae TaxID=1463164 RepID=A0A455MD31_9ENTR +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVSGP +AGLTAFLRQFGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TPATMVERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BFE020F +----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDFVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF07720 +----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDFVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. AY3-1 TaxID=2217817 RepID=UPI0011EC1A92 +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVQKRN +ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPQNRAPIIIAILSSK +DEKEATYDNQLVAEATEVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKE2_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERGTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLCSALPAGWLIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02058 TaxID=1703921 RepID=A0A1Q5CZ52_9ACTN +---TKASFDELEQKFDARLGVYAIDTGSGLSV-THRPDERFAYASTCKALLAGAVLDAVT +--VARLDRRVRYGRDELVANSPVTGKHVDAGMTLRELCDAAIRHSDNTAANLLFHELGGP +RGLQDALRGLGDRTTRCDRYETELSEAAPGDPRDTSTPRALAAGLRAYALGNVLGAKERA +LLTDWLRRNTTGDDVIRAGTPDGWVVGDKTGTGGYGTRNDIAVLWPPDSEPVVLAVLTRR +ETRDAVHQDALIAEAARVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhizobium TaxID=2613769 RepID=UPI0007E98722 +--NIEHRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAVGFVLARVD +KGQESLERRVTYGRDKLVDYSPLSEKHADTDMTIAELCEAAVTVSDNTASNLLLESFGGP +PALTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTAPDAMLDTLGNLTLGSVLAEPSSE +RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVKDLNPIFAEVGKMITE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A4Q9ZAJ9_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF8EA8F +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMNRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=J8D454_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTIADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAAYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. 13 TaxID=2035211 RepID=A0A2G6RM14_9BURK +--AAQTQLAALEQAAGGRLGVAAWRHGSEQRV-AYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMNVADLCAATLQYSDNSAANFLMKILGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLIIAVYYTR +EQKKADTNQDIITAATRIVS--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus swezeyi TaxID=1925020 RepID=UPI000B9D4FC6 +--EVKHHFAKLEDQFDARLGVFALDTGTNQTV-TYRPDERFAFASTLKALAVGALLQQKS +--IKDLDQNITYTHDDLVSYSPITEKHVNTGMTLKELSDAALRYSDNTAMNLILQQLNGP +KGLKKALRKIGDHVTNPTRFETELNDVQPGETRDTSTPRALATSLQAFTLGDALPIEKRE +LLIDWMKRNTTGDSLIRAGVPKGWEVADKTGAASYGTRNDIAIIFPPNGCPIVLAILSSR +DKKDAEYNDELIAGATKEVINEf +>[subseq from] class A beta-lactamase n=1 Tax=Proteus hauseri TaxID=183417 RepID=UPI0007E7F1F3 +--AIEQQLAALEKSTQGRLGVALINTADNSQI-TYRGNERFAMASTSKVMAVAALLKESE +QKTDLLDKNISIKQSDLVAYSPIVEKHLTTGMTLAQLSAATLQYSDNTAMNKILAHLGGP +EKVTQFARSINDITYRLDRSEPELNTAIHGDPRDTTSPLAMAKSLQALTLGDALGQYQRN +QLITWLKGNTTGDNSIKAGIPKQWIVGDKTGSGDYGTTNDIAVIWRENQAPLILVIYFTQ +QEQNAKPRKDIIVKATEIVTKPf +>[subseq from] Beta-lactamase n=3 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5TX89_9BACT +--EFENRVATIEARTGGRIGVAALDTASSKHL-DCRSEERFPMCSTFKFLAAAAVLKRVD +EKQEKLDRFVPYDAKDILEYAPVTKIHLKEGMTLGALCAAAIEQSDNTAGNLLLDAIGGP +IGLTNFARTIGDKVTRLDRKEPELNSAIADDERDTTTPAAMLADMLQLLLGNTLSPSSRH +QLEQWLQANETGASMIRAGVPTSWIIGDKTGRGANGATNDIAIMRPPGRAPILLVIYSAG +STATANDRAAVLAEAAKIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VDM053 TaxID=1053249 RepID=R8P7B2_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNTTGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0011507F0C +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALATGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax guangxiensis TaxID=1775474 RepID=A0A433MIG0_9BURK +--SAEARLAALESAAGGRLGVVGFNTGSGARI-QHRAHERFPLCSTFKLMLAAAVLERSA +KDASLLPRNVSYGKGDLIDHSPITEKHVATGMTVAGMCAATIQYSDNAAANLLLKVLGGP +SAVTAFARGIGDQAFRLDRTEPELNTSIPGDPRDTTTPAAMSDSIQRLVLGDALGAGQRD +QLRTWLLGNTTSTERFLAGVPAGWKVGDKTGAGSYGSTNDVGVLWPPTGAPIVLSVYLTF +PQKDAGNRNDVVASATRIAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FA98_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEVIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI00080DFD69 +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRVD +QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP +AAVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTMPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. K2I17 TaxID=2014743 RepID=A0A246PHB4_9BACI +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTYDTSTPKALATSLQAFALGDVLSTEKRN +LLIDWMKRNTTGDNLIRAGVPGEWEIADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DIEDAKYDDKLITEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF98157 +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLKKKS +--MEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLIEIGDTVTNPERFEPELNEVHPGETHDTSTPKALATSLQAFALGDVLSTEKRD +LLKDWMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000B432E83 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK +VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000871B9AF +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLKKKS +--MEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLIEIGDTVTNPERFEPELNEVHPGETHDTSTPKALATSLQAFALGDVLSTEKRD +LLKDWMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000B70C95F +-qATHKEFSQLEKKFDTRVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=R8K6Q1_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGGYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF01BE0 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK +VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Labrenzia sp. C1B10 TaxID=1397530 RepID=U7GN62_9RHOB +---LEKTVTGAESRLSARIGVAVLDTETGKTW-THRADERFPLNSTFKAFLCAALLEKGE +QGEVQPERRVKIRSQDLVSYSPVTEKKIGSGMTYLELCEAAVAISDNAAANLVLEAVGGP +AGLTDYLRGIGDTITRLDRTEPGLNEGRPGDARDTTTPAAAVATLQKLVLGNALSSTARA +QLTGWLLDNKVGNATLRAGLPEEWPVADKTGAGANGSRNNIGVIWPDDREPVVIAVYITQ +TDASFDDRNKAIADIAAALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2C5PQ40_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK +VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus swezeyi TaxID=1925020 RepID=A0A1R1RM60_9BACI +--EVKHHFAKLEDQFDARLGVFALDTGTNQTV-TYRPDERFAFASTLKALAVGALLQQKS +--IKDLDQNITYTHDDLVSYSPITEKHVNTGMTLKELSDAALRYSDNTAMNLILQQLNGP +KGLKKALRKIGDHVTNPTRFETELNDVQPGETRDTSTPRALATSLQAFTLGDALPIEKRE +LLIDWMKRNTTGDSLIRAGVPKGWEVADKTGAASYGTRNDIAIIFPPNGCPIVLAILSSR +DKKDAEYNDELIAGATKEVINEf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000826CBDA +----NQKFVQLEKKFDVRLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNP +--IEKLNDVIRYSKEDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSFGTRNDIAIVWPPDRAPIVLAILSKR +FTKDANYDNALIAEAAKVAFD-- +>[subseq from] Carbapenemase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0001BE63E6 +------PFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCXSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPSDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEF9C03 +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPEVNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. WSM3873 TaxID=1854056 RepID=A0A1A5RH95_9RHIZ +---ATKAVEALEARNGGRLGVMILDVGTNAAI-EYRADELFPMTSTFKFLAAAGVLKAVD +DGKAKLDDRIVYAASDVEPYSPITKDHVGDGMKLEDVCAAAVVWSDNTAGNLLLRVLGGP +QGLTRFARSLGDDVTRLDRTEPTLNTAIPGDKRDTTSPRAALGDARRILLGDALSPASRK +RLEAWLIEDKVGAARIRAGLPATWGIGDKTGSGDNGTTNIVAILWPPEGAPILVAVYYTG +STAPRASREAVHRDMARIIVETf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=L7QJP2_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSSVSEKHLAGGMTVGELCAAAMTMSDNRAANLLLATVGGP +AGLIAFLSQIGDNVTRLDRWETEVNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF231B2 +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEELVDYSPVTEKHIDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPLHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK +DEKEATYDNQLIAEATEMIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar argentinensis TaxID=180880 RepID=A0A243K6J9_BACTU +-----DSFVKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SAFEKILREIGDTVTTSERFEPELNEVHPGETHDTSTPKAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=A0A5C4NVA1_9BURK +--TAQTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDTWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. HH104 TaxID=1537276 RepID=UPI0008739D4F +--TAQTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDTWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000CD86566 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQTS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK +VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0G8EQ42_BACCE +-qATYKDFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Class A beta-lactamase n=2 Tax=Xanthomonas TaxID=338 RepID=A0A643E0Y0_9XANT +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000F472DF6 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDER--------------- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEE5605 +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000CD8B1EA +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000B445703 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus cereus TaxID=1396 RepID=R8I5E4_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFD1A45 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A7XC64_9BACI +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +QGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0013D4B9DB +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A7II52_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B0HRP0_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A172WCD1_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSAGSPR +HLLQWMVNNRVAGPLIRSVLPAGWFIAEKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Haematospirillum jordaniae TaxID=1549855 RepID=UPI00143311E3 +---AVQRLSDLESTFDGRLGVFAFDTSSGAAL-AWRSEERFPLCSTFKAFLAAAILHRST +SDIGLLDRVISYPLEELVFHSPVAQQHVHSGMSVRDMCAAAIQYSDNTAANLLMRILGGP +DAVTAFMRQTGDMDFRLDRWETDLNTAIPGDLRDTSTPVAMARSLDRLLFGDVLSDTHRA +LLQDWLKGNATGASRIRAGVPDGWMVGDKTGSGSYGTANAIGVLWPPGRKPVIVSVYTTQ +HYRGAVWRNDIVAQATRIIVD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. CD3-1a TaxID=2587158 RepID=UPI0011240B7A +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGEIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=A0A2S6Y5K6_9XANT +--ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD +KGELTLAKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG +ATVDAAARDAALKAVAAAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00065B4CA1 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LETLDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +TEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. LK7 TaxID=1628209 RepID=UPI0012E01217 +----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRTDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B5IBW9_9BACI +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Class A beta-lactamase n=9 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A6B3KGF0_XANEU +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRVD +QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP +AGVTAFLRGIGDAQTRTDRYEPQMNRFADDDPRDTTTPAAMAATLRTLLLGDALHPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2C4YYV4_9BACI +-----DSFVKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGNALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKG1_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILgSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHCSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLTSRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. BJB312 TaxID=1560197 RepID=A0A2G3M1W1_9BURK +--AAQTQLAALEKSAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLENSLLAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLVIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Stappia indica TaxID=538381 RepID=UPI0009F3FBFB +--DIEGRLAALEREQGGRLGIAIHDVASGQTF-GNRLDERFLMASTFKLMLAAFVLARVD +REEEQLDRRIPFTKRDLVSWSPGTEKHAGGPLTVAELCEATMTMSDNTAANLLLASFGGP +AALTGFARSLGDETTRHDRTEPALNADGPDDERDTTTPAAMAETLRKLLFGDALSRRSRD +RLTAWMVTNRTGDARLRAGFPADWLVGDKTGTSGKGHANDIGVAWPSGRGALIVIAYCEM +PKAEAKTRDATIAEIARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000C78370A +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVGYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDASYNNALIAETAKVALN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=R8NA09_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKALAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0008651ECA +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRYETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas axonopodis TaxID=53413 RepID=UPI0009960FA7 +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora echinospora TaxID=1877 RepID=A0A1C4XQ95_MICEC +---ADRSFDALEARFAARLGVFAIDTGSGATV-THRADERFAYASTFKALIAAALLDATT +--PAQLDRVVRYTRADLLAHAPVTREHVGTGMSLRDLADAAVRYSDNTAANLILAELGGP +AGLARHLRALGDRTTKPVRTEPALNEATPGDERDTSTPRALATDLRAYVLGDALDAGDRA +LLTDWLRRNTTGDALIRAGVPAGWTVGDKTGTAAYGTRNDIAVLWPPEGAPIVLAVLSSR +AAEDAEHDDALIAEATRVTLD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus intestinalis TaxID=1963032 RepID=A0A657RHD5_9BACI +----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYTKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Bordetella genomosp. 1 TaxID=1395607 RepID=A0A261SHX0_9BORD +--DLPRQLARLEARDGGRLGIAVLDTGSPFTL-AYRADERFPLCSTFKWLAAAAVQARVQ +QGQDLPERRIRYGAPDMVAYSPVTQQHLTDGMTLDALCEAAVVWSDNTAGNLLLSTIGGP +PGITAFARAMGDDLTRLDRIEPALNEARPGDERDTTTPLAMQRLLQKVVLGDGLAPAQRE +RVQAWMRGCRTGDTRLRAGVPGDWVVANKTGAGGNGTNNDVGVLWPQRGAPVVVAAYLTG +SPASREAQNALLAEAARLIA--- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Pectobacterium brasiliense TaxID=180957 RepID=UPI00057CC6E0 +-pDTLDTVKDAENKLKARVGYTELDLTNGMILeGYRPEERFPMMSTFKVLLCSAVLSRVD +SGKEQLDRRIHFDQSDLVTYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLSTIGGP +QELTIFLRKTGDHVTRLDRWETALNEALPGDERDTTTPKAMAETLHKLLTGKILTVASQQ +QLMDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYLTG +SQATIEERNKQIAEIGTSLIKHw +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011AB452C +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus intestinalis TaxID=1963032 RepID=UPI0009A2B316 +----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR +FTKDANYNNALIAEAAKIVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDEBBCC +-kDIEKQLTALEKQTGGRLGVYVLDTKTKASF-AHRQDERFAMCSTFKALAAAFVLARVD +KGEEKLDRRISISKKHLLSYSPVVEKQVGGGMTVGELCDATVTYSDNAAANLLLASFGGP +KGLTDWLRSIGDGTTRLDRIEPELNEAKIGDPRDTTTPMAMTQTLGKLLLEDVLSPASRD +QFSAWLVANTTGDRRLRAGLPKGWTIGEKTGTSGHGEAGDIGFMRPAEGHTVLASVYIAE +GKKPTKDLEPVFGEVGKLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BAG3X2-1 TaxID=1053183 RepID=J7XPQ3_BACCE +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNATGDKLIRAGVPNDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SWA1_9BACT +--DAEARLAELERAHGGRLGVAVLDLANGRRI-GHRADERFLMLSTFKTLAAALVLARVD +RGEERLDRRIVFSESDLVVWSPVTENRVGRAMTLAELCEATITLSDNTAGNLLLDSFGGP +AALTDYLRSLGDEVTRLDRIEPDLNEDAPGDLRDTTTPAAMLETLHKLLFGDALSRHSRD +QLNAWLIINKTGDQRLRAGFPENWLVGEKTGTNRSGTANDAGVAWPIDRGPILVAAYCEM +SSISPEKRNAVLAEVGRIAA--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. B1-WWTP-T-0.5-Post-4 TaxID=2653219 RepID=UPI00126257E0 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia aromaticivorans TaxID=2026199 RepID=A0A248VRZ3_9BURK +---IRRRLAEIEVASGGRLGVSIVDTMSGLHA-GWRTDERFPMCSTFKVLAVGAVLARTD +RGEEDLQRRVVFSQNDVVSNSPATSKHTRELMSIAELCKAAITLSDNTAANLLLATFGGP +AGLTAFARGLGDGITRLDRNEPTLNEAMPGDPRDTTTPNAMLGNLRELLLGEHLSPPSRA +QLLAWLAANETGGARIRARLPKEWGVGDKTGTGDHGTANDVAILWPPGRGPVLVTVYLTE +TDGNAARSNAAIANVGALVVA-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001145D60D +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKATATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNKAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0011A4D009 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LETLDQRITYTHEDLSNYNPITEKHVNTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus indicus TaxID=246786 RepID=A0A084GIY5_BACID +----NHDFAELEEKFDAKLGVFALDTGTNQTV-TYNPDERFAYASTHKALAVGALLQQIS +--IEDLNQRITYTREDLVNYNPVTEKYIDKGMTLRELADASLRYSDNTAGNLILNQLGGP +AGFKKALEAIGDDITSPERMEPDLNEVNPGETHDTSTPRALAASLQDFILGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPEGWEVADKTGSGSYGTRNDIAIIWPSKGDPIVLAVLSSR +EKKDADYDDKLIAEATEMVMN-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora aurantiaca TaxID=47850 RepID=A0A3M9KNC6_9ACTN +------ELAALERRSGARIGVYALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFERALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD +LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR +DSRDAEPDDALVAQAARAAVT-- +>[subseq from] Uncharacterized protein n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A1W0D7S2_9NEIS +----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPLCSSFKGFLAAGVLAQSQ +DKPGLLDKRIRYSKAALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLKEINGP +AALTAFMRSIGDASFRLDRLEPELNSAVPGDPRDTSTPKAVAESAQKLALGKALPEPQRQ +QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH +AKKEAKHSDEVIAAAARAALEAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A172WCF4_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQP +QLLQWMVDDRVAGPLIRSVLPAGWFIADKNGTGKRCARAIVALLGPNNKAKRIVVIYLRD +TPANMAERNQQIAGIGAALI--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas citri pv. mangiferaeindicae LMG 941 TaxID=1156940 RepID=H8FK52_XANCI +--MLRAQWAQIERGAGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis subsp. higo TaxID=132266 RepID=A0A243KBM6_BACUH +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRITMSDRFETELNEAIPGDIRDTSTARAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Schlegelella thermodepolymerans TaxID=215580 RepID=A0A2S5T2H5_9BURK +--------LAIENESRGRLGVAVLDTATGVLQ-GHRLDERFPMCSTFKWVLGAHVLHRVD +QGLERLDRRIVYGPEALVPWSPVTERHVGTGMTVGQLCEATITLSDNAAANLLLATLGGP +QGLTRYIRSQGDTVTRLDRTEPQLNEARPGDPRDTTSPRAMAQLLRTVVLGEGLSRSGRA +QLVRWLQDCKTNGQRLGAHVPAGWALGSKTGSGARGATNDVGIYWPADRPPVVVAAYLAE +TQASDAARNAALARVAQQVTRAy +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase CRH-2 n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A2R2V0K7_9NEIS +----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPLCSSFKGFLAAGVLAQSQ +EKPGLLDKRIRYSKTALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLKEINGP +AALTAFMRSIGDASFRLDRLEPELNSAVPGDPRDTSTPKAVAESAQKLALGKALPEPQRQ +QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH +AKKEAKHSDEVIAAAARAALEAf +>[subseq from] class A beta-lactamase n=1 Tax=Pectobacterium polaris TaxID=2042057 RepID=UPI000D60E570 +-pDTLDTVKDAENKLKARVGYTELDLTNGMILeGYRPEERFPMMSTFKVLLCSAVLSRVD +SGKEQLDRRIHFHQSDLVTYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLSTIGGP +QELTIFLRKTGDHVTRLDRWETALNEALPGDERDTTTPKAMAETLHKLLTGKILTVASQQ +QLMDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYLTG +SQATIEERNKQIAEIGTSLIKHw +>[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI0013EF3CE9 +-tEMKDDFAKLEEQFDAKLGIFALDTGTNQTV-AYQPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPALNEVNPGETQDTSTARALATSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVIK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ru62 TaxID=2080745 RepID=A0A2S4ZL22_9ACTN +--AVHAELAELEQRHGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDRA +-GCAPLDRVVHYPPHDLLPNSPRTEENLATGMTVADLCAAAIQYSDNAAGNLLLRELGGP +AGLTRFHRSLGDEVSRLDRWEPELNTAIPGDPRDTTTPEAIAASLERVTLGRALSRADRE +RFVGWLKGNTTSSARFRKGLPKEWVVADKTGTGDYATANDIGVAWTSRRTPLVLAVLSGK +DTPDAPVDEALIADAAAVVAR-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Verrucomicrobia bacterium 13_2_20CM_54_12 TaxID=1805419 RepID=A0A1Q6VQM8_9BACT +--DAATRIAAVEARIGGRIGVAALDTGNTKHV-EHRADERFPMCSTFKFLAAAAVMKRVD +EKKEKLERFVPYGAKEILEYAPVTKEHLKDGMTLGALCAAAIEQSDNTAGNLLLDAIGGP +SGLTNFVRSLGDRLTRLDRIEPELNSAIPGDERDTTTPAAICSDIQRLLLGDALSEASRR +QLEDWLQRNETGGPMIRAGVPKNWILGDKTGRGSNGATNDIAIMRPPDRAPILLAIYSVG +STATPTDRAAAVAEVAESFV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A7VWB3_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLHKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0014447161 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDNRFAFASTSKSLAVGALLRKNS +--LETLDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus (strain G9842) TaxID=405531 RepID=B7INI5_BACC2 +----NDSFAKLEKEFDAKLGIYALDTDTNQIV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A0K0QLK7_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRITMSDRFETELNEAIPGDIRDTSTARAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. K4S16 TaxID=1316147 RepID=UPI0011EED064 +--RVTRQIGRLEATHHARIGAFAIDTGTGRAV-AHRPDERFPFASTFKAMACGAVLRKAR +QDPGLLDRVIHYTKDDLVEYSPVTEKHVDTGMTVADLCHAAITQSDNTAGNLVLKQIGGP +AGLTAFFRSLGDTVSRSDRWETDLNIWKPGEVRDTTAPRPWAGNLRALTTGGALVPADRE +RLVDWMKATVTGDKRIRAGLPNNWTVGDKTGTGGYGTANDIAIAWPPSGAPLVIVITTNR +FAPDAAADDQAVAQTARVLAN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00115574C5 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRITMSDRFETELNEAIPGDIRDTSTARAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZHY7_KLEOX +--AIQQKLTNLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTXKVMAAAAVLKQSE +SHPDVLNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAK----------------- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2C2I8U2_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI00065BE107 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEBCB63 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGILLQQNS +--IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNTTGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF21882 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2B3KGW4_BACTU +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=R8HW30_BACCE +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKTS +--IEDLDQIIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYNDKLIANATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF72B1A +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=Q9L6I3_SERMA +--ELDSALARLEQQHHGRLGLAYIDSGSGESY-SYRGEERFAFCSTFKAVLAGAVLQRSV +SQPGLLDKRVHYAATDLLAYAPITKTHLDKGMRIGELAAAAVQYSDNTAANLLLQEIGGV +QALNRFVQGLGDPAFRLDRIEPHLNSAEPGDVRDTTTPLAMAHTLQAMTLGKGLPQAQQA +QLVSWLKGNTTGAQRIQAGVPAGWQVGDKTGTGGYGTTNDIAILWPEQGAPKVLAIYFTQ +PAADAEANRAILAEATRLVLQ-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A1A9PYX7_9BACI +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLKKKS +--MEDLNQRILYTREDLVNYNPITEKYVNKGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLIEIGDTVTNPERFEPELNEVHPGETHDTSTPKALATSLQAFALGDVLSTEKRD +LLKDWMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFE1B40 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=A0A2A7H589_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=R8HVM0_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNTTGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00084C5DD1 +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADNRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAITKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=9 Tax=Bacillus TaxID=1386 RepID=A0A2C3MI64_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRITMSDRFETELNEAIPGDIRDTSTARAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=J7W2D0_BACCE +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPTNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium TaxID=379 RepID=UPI00056B94B5 +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GYREEERFPLCSTYKALAVGFVLTRVD +QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCGAAITLSDNTAGNLLLQSFGGP +AALTSWLRSTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLINWLVGNTTGDNRLRAGLPKEWKVGDKTGTGNNGCFADIAVVWPPDRGPILVTTFVAE +GTAPAKDIEAVFADVGKIVT--- +>[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus lautus TaxID=1401 RepID=A0A2A5LJM2_PAELA +-----------AAEDGIELSVGIQDLSGGGKI-QVGSSDVYYAASTIKIAIVTALMQDIE +AGKYALEQTIQVQPEQVVGGAGSLKDKFPLDITIESLARLMITQSDNTATNALIDLL-GF +ERINAFIEEQGFETMQLGRKMMTPAKS--PAADNYVDGEELLTLLERIYAGEILTAKSRD +QILAWMKAQEV-KTKFGAALP-GKPIAHKTGELGD-VSHDIGYFLVPGRE-AAVTVLTKV +TKKAQELGNPVVQRAAKAVYN-- +>[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus lautus TaxID=1401 RepID=A0A2A5LJM2_PAELA +------------EDKGIRVSVGLKDLSGDREL-LLGSRQSYMPASTIKMALVSGLMKEVD +AGKLTLEETVKVEKEDVVGGTGSLQKETPQDVTIERLARLMITQSDNTATNVLIDVV-GL +DEVQNLMDELGLDVMHLGRKMFAAA--PTPEQDNYIDAEDLVHLLAYIHSGSFLSDNSRD +QIIDWMKAQEV-DTKFGAALP-DAPIAHKTGENAN-VTHDAGYFLVPGRE-IAISVLTEV +TTEAQAIGNPVVQEIAKAVYE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF7863E +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000A27CE72 +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKTS +--IEDLDQIIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYNDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2A7ZLU9_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRITMSDRFETELNEAIPGDIRDTSTARAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0009AC354E +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinospica acidiphila TaxID=304899 RepID=UPI0005256257 +------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDRRP +--GARLDERISYGAADLVPYSPVTEKHTGQGMTLRELCDAAVRYSDNTAGNLLLRDIGGP +RGLTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVHGDALPAAGRA +LLTDWLVRNTTGDDRIRAGVPRGWKVGDKTGTAEWGRANDVAVLWPGGGSPLVLSVLTDR +PDRAASGQDELVAEATRRVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. rho-1.1 TaxID=2506429 RepID=A0A545ZLV9_9RHIZ +--DAGAQLAALEKRTGGRLGVAVLDTETNISL-GNRETERFPMFSTWKALAAGFVLARVD +QGKEKLDRRVSFGKEALVAYSPVAEKHAGTDMTIAELCEAAITVSDNTAANLLLDSFGGP +AALTDWLRTTGDTETRLDRREPELNEAKKDDPRDTTTPDAMLDTLGLLTLGNTLSDASST +MLTGWLVAATTGKDRLRAGLPAEWKVGDKTGTGAQGMAADIAIVWPPERGPILVAAYIAD +ATAPTAEINAVFAEIGKMVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF97C66 +----NDSFAKLEKEFDAKLGIYALDTGTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYNREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGT +SEFKKSLREIGDTVTNPERFEPQLNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKENAKYDDKLIAEATKIALD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00114E51F2 +-qATHKEFSQLEKKFNARLGVYVIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLITEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2B0EC63_BACTU +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAEVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009448B17 +----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPQNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00115DAA0C +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNIIFNKIGGP +KGYEKALRKMGDPVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus vallismortis TaxID=72361 RepID=A0A410WNS2_BACVA +----DEKFVQLEKKFDAKLGVYAIDTGTNKTI-SYRSNERFAYASTYKVLAAAAVLKKNT +--IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEIAEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNNLTPDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPHRAPIVVAILSNR +FTEDAHYDNALIAEAAKVVLNNf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces armeniacus TaxID=83291 RepID=A0A345XIY1_9ACTN +--EAQREFGRIEEKYGARLGVYAVDTRTGREL-SYHADNRFAFASTFKALIAGALLQRDS +--VKELEKRVTYKRSDLVPHSPVTEKHVESGITVREAMDAAVRYSDNTAANLLFRELGGP +DELQAALRRLGDDTTHSDRVEPELNETKPGDIRDTSTPRAMAGSLRAFTVGKALPEDKRK +ILTTMMRTNTTGSKLIQAGAPKGWKVGDKSGAADYGTRNDIAVVWPPGRAPIMLAVMSDR +KSKDAEYDDALVADAAKAAFDVy +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF3D5EB +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B3FG87_BACCE +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C2I5H5_BACCE +----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKSLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Prauserella shujinwangii TaxID=1453103 RepID=A0A2T0M1G3_9PSEU +-----EEFAELEREFSARLGVYAVDTGSGREV-THRAGERFAFASTIKALLAGAVLRQRS +--LGGLGEVLTYTADDLVSHSPVTERHAGAGMPVRALLDAAVRYSDNTAANVLLDDLGGP +EALTAALREIGDDTTRSDRYETELNTAVPGDVRDTSTPRAMATSLRVFVLGDALPPGERA +FLTELLRTNTTGDTLIRAGVPAGWPVGDKTGAGGYGTRNDIAVVWPPGRDPIVLAVLSDR +DSPDASHDDALVARAAEVVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF4EC42 +------SFVKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGNALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus dakarensis TaxID=1917889 RepID=UPI000B44958F +------VFAKLEDKFDARLGVFALDTGTNQTV-TYRSDERFAYASTHKALAVGALLRQKS +--IADLNQRITYTHDDLVNYNPITEKHVDTGMTLKELCDAALRYSDNTAENLILEQLGGP +SGLEQSLREIGDNVTNPERFEPELNEVEPGETRDTSTPKALAASLQAFTIGDALPAEKRS +ILTDWLKRSTTGDTLIRAGVPKGWEVGDKSGSASYGTRNDIAIIWPPKGDPIVLAVLSSR +DKKDADYDDKLIAQAAKEAI--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1C4DPV5_BACTU +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +QGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1C4DBR8_BACCE +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KRYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces subrutilus TaxID=36818 RepID=A0A5P2UIU8_9ACTN +--STHRALRDLEEEFGARLGVYAIDTGSGRCV-AHRADERFAYCSTHKALTAAAVLDRNS +--LAELDEVVRYCAADLVANSPITEKHVDTGMTLRELCDAAVRFSDNTAGNLLFAELGGP +KAFQAALAALGDRTTRADRVETALNEAVPGDLRDTSTPRALVADLRAYALGDVLPADKRA +VLVDWLRRNTTGGRLIRAGVPADWQVGDKTGAGSYGTRNDIAVAWPPAAAPVVLAVLSSR +PARDAAYDDALIARAARVVVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0008FE2680 +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADNRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAITKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +NKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0E1MK66_BACCE +-qATHKECSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRYSDNTAGNILFHKIGGP +KGFEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTIGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=B5UYF1_BACCE +----NHAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH +DKEDAEYDDTLIADATKIVLE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID7810 TaxID=2690329 RepID=UPI00073DF495 +----RAELAELERRYGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDRA +-GCAPLDRVVHYPPHDLLPNSPRTEENVATGMTVAELCAAAIQYSDNAAGNLLLREVGGP +AGLTRFYRSLGDEVSRLDRWEPELNAAIPGDARDTTTPEAIAESLERLTLGRALAGADRE +RFVGWLKGNRTSDERFRKGLPKDWTVADKTGTGDYASAHDIGVAWTTRGTPVVLAVLSSK +STPDAPVDQALIADAAAVVAR-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000D0440C4 +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAAAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BFD36F4 +----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQDYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVFK-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. AD80 TaxID=1528773 RepID=A0A2N7RWM0_9BURK +---AEAQLAALEQAAGGRLGVAAWRTDNSARV-SHRADERFPLCSTFKAMLAAAVLARSA +SQPGLLDQHVRYEKKELVTYSPITEKHLDDGMSVADLCAATLQYSDNSAANFLMVILGGP +QAVTAYARSIGNMVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGTSLPAPQRQ +LLDSWMRGNTTGDKRIRGGLPAGWAVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKNAPTNQDIISAATRIVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Lysobacter antibioticus TaxID=84531 RepID=A0A0S2F6A6_9GAMM +---WSAQLRVLEKNSGGRLGVGMLDTGSGQHF-DWRGRERFPMCSTFKFLLAAAVLREVE +RGKLDLQKKIPIAKSDLIAYSPVTEPLAGSSASVAQLCEATMTLSDNTAANLLLPLVGNP +AGLTAFLRGIGDPTTRLDRKEPELNSAIPGDPRDTTSPLAMVATMRKLLLQDGLQPASQK +QLTAWLVANRTGDKRLRAGVPKGARVGDKTGTADT-TSNDLAIIWLPDRAPILLTCYLTG +STLDGPGRDAIHASVARLVF--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZR30_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDXQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIA---------- +>[subseq from] Beta-lactamase n=1 Tax=Polyangium sp. SDU3-1 TaxID=2567896 RepID=A0A4U1HHD7_9DELT +----DAEFTKIEQNLGGKIGIAALDTGSGATL-HHRHDERFPMCSTFKMVLAGAVLARVD +GGKEKLDRTIAYGEAALLEHAPVTRAHVKEGMTVEALCEAIVLVSDNTAANLLLDTMGGP +EGLTAYFRSLGDTVSRLDRKEVELNTAIAGDERDTTTPSAMVSTMKRLLIGDALSPASRE +KLLGWMIACNTGKDRLRAGLPRDWRAGDKTGTGMNGAANDVAIAWPPGRPPVLLAVYAWG +SEGPLPRINAAHAEVAAVVSRFf +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas citri pv. vignicola TaxID=473426 RepID=A0A220WES6_XANCI +--MLRARWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSIGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGVGDAQTRTDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGGPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A4U2P2X6_BACCE +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF3364D +hqATYKDFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEMIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus sp. TaxID=229037 RepID=A0A3D2BNA1_9GAMM +--AIEQQLSALEKSTQGRLGVALINTADNSQI-TYRGNERFAMASTSKVMAVAALLKESE +QKADLLDKNISIKQSDLVAYSPIVEKHLTTGMTLAQLSAATLQYSDNTAMNKILAHLGGP +EKVTQFARSINDITYRLDRSEPELNTAIHGDPRDTTSPLAMAKSLQALTLGDALGQYQRN +QLITWLKGNTTGDNSIKAGLPKPWIVGDKTGSGDYGTTNDIAVIWRENQAPLILVIYFTQ +QEQNAKSRKDIIVKATEIVTKPf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI25_KLEOX +--AIHXKLTDLEKRSRGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQE------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8W2_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQERLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAATTMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B45579C +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KRYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis subsp. tolworthi TaxID=1442 RepID=A0A0G4D2Y5_BACTO +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFTSTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2T0E1Y0_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTNWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI0011559941 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00130DF631 +--NIDEKFAQLEDDFDAQIGVYAIDTGTNQAI-EYRPEERFAFASTYKALAAAIVLQQNS +--MEDLNEVISYSEDDLVPYSPVTEKHVDTGMTLLELAEAAVRTSDNTAGNLLFKALGGP +AEFEQALRDIGDHDTQSDRYEPDLNMFSPEDPRDTSTPKALTTSLRAFVVGDLLSDQARE +RFTNWLQGNATGDTLIRAGAPEGWEVGDKSGAGSYGTRNDIAVVWPPNREPIVITIMSRH +NTEDAEYDDALIAQAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis Bt18247 TaxID=1423143 RepID=A0A1C9BTJ3_BACTU +-qATHREFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIISAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis MC28 TaxID=1195464 RepID=K0FM29_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK +VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B1C02F +-qATHKECSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRYSDNTAGNILFHKIGGP +KGFEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTIGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF5C10E +----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQDYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. WN066 TaxID=2547811 RepID=A0A4R5VKE7_9BACI +--QTHREFAELENKYDARVGVYAIDTGTNRKV-SYRSQERFAFASTYKALAAGALLQHYS +--IGQLDELVTYNSEDIVPYSPITQLHIDTGMTLREVIEAAVRHSDNTAGNLLLEKLGGP +EGFETALRKIGDNVTQVDRYETDLNSAVPGDTRDTSTPKALATSLKAFAVSDLLPAEKRK +ILTDWMRGNTTGNALIRAGAPTGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR +DTQNATYDNTLIAEAAKVALN-- +>[subseq from] Beta-lactamase n=2 Tax=Caulobacter sp. BK020 TaxID=2512117 RepID=A0A4R3GYA2_9CAUL +---ISRNIAALEARSGGRLGVAILDTADGEVF-AHRGDERFAMCSTFKALVAGLVLKRVD +QGQERLDRLIRYGRGVLLAHSPATERHVEDGMTIGALCEATVTLSDNAAANLLLHTFGGP +PALTAFLRGLGDSVTRLDGYEPGLNVVRPGEIHDTTSPRAMLATLRALTLGPVLSPASRQ +QLVAWLVANQTGDKRLRAGLPAGWKVGDKTGSWGDGNTNDIAVIWPPGRPPLLVTAYLSR +STLDDDGRNAVIAEVARLAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000994FB8C +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKTLATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000D63414F +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTSMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGAHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Xenophilus sp. E41 TaxID=2282216 RepID=UPI000EF60994 +----AAALARLEDGLDGRLGVFAIDTASGATL-GHRASERFPMCSTFKAILAGAVLARSW +REPGLLDERVRYTKADLIAHSPITGRELARGMTVAELCAATVQYSDNAAANLLLRRIGGP +EALTKQARAWGDSTFRLDRWETALNSALADDPRDTSTPEAMARLLRTLAVDDGLPSAQRA +RLQDWLRGNTTGGARIRAGMPAAWTVGDKTGTGAHGAASDIAVVWRPQAAPLVLAVYTRL +EAQDAKPRDDVIAAASRIVA--- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Rhizobium TaxID=2613769 RepID=A0A1W6PQ43_9RHIZ +--NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD +KGQESLERRVTYGRDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP +PALTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTAPDAMLDTLGNLTLGSVLTGASCD +KLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE +ATAPVKDLNPTFAEVGRMITE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2B8TPB4_BACTU +----SQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF955CC +----SQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFDBCCC +----SQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. WSM3866 TaxID=422271 RepID=A0A2A3B9A3_9RHIZ +---ATKAVEALEARNGGRLGVMILDIGTNAAI-EYRADELFPMTSTFKFLAAAGVLKAVD +DGKAKLDDRIVYAASDVEQYSPITKDHVGDGMKLEDVCAAAVVWSDNTAGNLLLRVLGGP +QGLTRFARSLGDDVTRLDRTEPTLNTAIPGDKRDTTSPRAALGDARRILLGDALSPASRK +RLEAWLIEDKVGAARIRAGLPATWGIGDKTGSGDNGTTNIVAILWPPEGAPILVAVYYTG +STAPRASREAVHRDMARIIVETf +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea vagans TaxID=470934 RepID=UPI00050F3AFE +-qTLESQFKALESKSEGRLGVAVIDTSDGSTY-SWRGNERFPLCSTSKVMAVAAILKKNE +SDYHLLDKKIHINKSDMVNYNPVTQKHTGSYMTVAELSAAALQYSDNAAMNKLLAYLGSP +QQATQFARTIGDKDFRLDRNEPGLNTAIPGDTRDTTTPSAMADSLNKLVLGTALKEAQRT +TLAEWMKGNTTGSNSIKAGLPGAWVVADKTGSGDFGTTNDIAVIWPKNHAPVILTAYFTQ +HSKDATARRDVLASAAKLVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000DEEA7C3 +-----DSFVKLEKEFDAKLGIYALDTDTSQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPXNKKPIVVAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9R8D1_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKITHRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus intestinalis TaxID=1963032 RepID=A0A136GEC8_9BACI +----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR +FTKDANYNNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A7VR90_9BACI +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLINYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLIEIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKRPIVLAILSNH +EKEDAKYDDMLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00124DFDF5 +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADNRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKTVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B7F1183 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKL +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacter henricii TaxID=69395 RepID=UPI0005511B91 +--DLNSRMADLEKRSGGRLGVAALDLKTGQRL-AWRAGERFRMCSTFKAPLAAHVLRRVD +QGREDLSRKVTYGKAVLMGNSPITEKHVADGLTIGQLCEATIAWSDNAAANLLLDAVGGP +KALTRFLRSMDDQVTRCDRYEPELNGGAASDPRDTTTPAAILDTWKTLLLGDALSATSRA +QLTTWLVANRTGGKRLRAGLPPGWRVGDKTGNDGKSITNDIAIAWPADRPPILIAAFLAG +SSPDDDVRNAIHAEAARILV--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=A0A381LR22_9XANT +--ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD +KGELTLAKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG +ATVDAAARDAALKAVAAAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI000CEE6500 +--ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD +KGELTLAKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG +ATVDAAARDAALKAVAAAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus intestinalis TaxID=1963032 RepID=UPI000B5A1875 +----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR +FTKDANYNNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000BAF2448 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTRAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNTLIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. Co1-6 TaxID=1806507 RepID=UPI0012E098A5 +----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALTTDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSHGTRNDIAIVWPPDRAPIVLVILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. NEAU-DD11 TaxID=2683234 RepID=UPI00135F8197 +--DATQALAGLERRAGGRLGVAAWRRGGADVI-AWRGDERFPFCSTAKVMVVGTVLTLAA +RTPGLLDERVRYKKADLVSWSPVTEQHVDDGMTIADLCAAALQVSDNSACNLLLDRIGGP +AAVTAFARRIGDTAFRLDRRETELNAAIPGDPRDTTTPRAMARSLEALLLEEALAPDARR +RLLDWMFANTTGKERIQAGFPADCRVADKTGTGAHGTTNDVGLVFPPQGQPVIVAVYYTG +SKSD----SKVVADAAAIVAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0008726FD4 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAAGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=R8LNY1_BACCE +----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQDYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Edaphobacter modestus TaxID=388466 RepID=A0A4Q7YWS7_9BACT +-eDLSTTLAALETRSKGRLGVAIL-FPSGKQV-THRADERFPMCSTFKFLAASLILQRVD +QGKEHLDRAVAFSKSDLVTYSPETEKHAGGSMTVAELSKAALTLSDNTAANLLLASFGGP +PALTAFARSIGDPLTRLDRNETTLNESTPGDPRDTTTPNAMLANLQRIFFGNVLKPASRQ +QLTDWMLANTTGKPKFVAGLPSTWKVADKTGSGEHGSNNDIGVLYPPDGEPIFITSYLTE +TAISTDERNAIHADIASAIAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium alamii TaxID=492774 RepID=UPI0005622480 +--DIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +KGDESLDRRVKYGKEKLVTYSPETEKHAGGDMTMAEICKAGITLSDNTAGNLMLESFGGP +AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN +QLVDWMIANTTGGARLRAGLPSDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYIGE +ATVKMDEFNPVFAEIGKMITE-- +>[subseq from] Beta-lactamase n=1 Tax=Massilia psychrophila TaxID=1603353 RepID=A0A2G8SWP6_9BURK +---FARDVAKIEAASGGRLGVAAFDTGRNSQL-SWRGDERFPMASTFKVLAAASILARKP +---GLLATRIRYTQEDLVPYAPVTERHLADGMTNAELCAAAVQVSDNPAANLLMRQVGGP +AGVTAYARLLGDAMFRLDRWEPELNSAIPGDARDTTTPLAMMRTLHKLALGDALAPPARK +LLVDWMLTSTTGAERIRAGVPHDWNVADKTGSGGHGTTNTIAVMWPPGRSPIVIAVYFTQ +SP---RQRNDVVAAAARAVNAAf +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. YR522 TaxID=1144342 RepID=J3HJS6_9BURK +---IAQKLAELEKKSGGRLGVMAIDNASSDRV-GYRQSERFPFCSTFKIVLVGAVLNRSL +EDSTLLQRRLRFGARDLVSYSPVTEKAVGAGMTVSGLCAAALQYSDNTAANLLIAELGGI +GAVNDYARRIGDTEFRLDRTETALNSAVPGDPRDTTTPQAMAQTMQKLTLGELLPALQRR +MLIDWLRGNTTGGARIRAAVTRDWQVGDKTGSGDYGTTNDVAVIWPTNASPVVLVIYFTQ +TAENAPMRNDVVADAARIVIEHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FB68_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTASLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus panacihumi W25 TaxID=1408254 RepID=V6M907_9BACL +--DADQQLGQLEKEYDARLGIYAIDTETGRTV-SYRPDERFAYTSTFKPLAAGALLLKKP +--LDELDKVITYKKEDLVTYSPVTEKHVEKGMTLREISDAAIRYSDNTAGNLLLKELGGP +AGLETVLQEVGDHITKPERYETDLNEAVPGDIRDTSTPKALATTLKAFTVDGVLPAEKQD +VLIDWLKRNTTGDELIRAAVPEGWTVGDKTGAGSYGTRNDIAVIWPPNQAPIVMAVLSSR +TEQDATYDNALIAKAAKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=BLAC_BACTU +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKRIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFBE7FC +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVQKRN +ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWSQNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rummeliibacillus pycnus TaxID=101070 RepID=UPI000C9BFDE9 +---IHREFENLESKFDAHLGVYAIDTGTNRKI-SYRSNERFAYASTYKALAAGALLQQYS +--IDKLDELVTYTSKDIVSYSPVTQLHVDTGMTLREVIEAAVRYSDNTAGNLLLEKLGGP +KGFETALRQIGDNVTQVDRYETDLNSAIPGDKRDTSTPKALATSLQAFAVSDLLHTEKRT +ILTNWMRGNTTGDALIRAGAPTGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSNR +DTQNATYDNRLIAETANVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=BLAC_KLEPN +-----EQIKQSESQLSGRVGMVEMDLANGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAGIGQ------ +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000BF9A2DE +----NDSFAKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDEKITYTREDLSNYNPITEKHVDTGMTLKALADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPKEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI001145EDA8 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVLVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus polygoni TaxID=1235259 RepID=UPI0011F2120D +-qTTDNDFAQLEKEFDAKLGVYAIDTGSGKII-DYQADERFAYTSTFKALAAGAVLQQNT +--MEELNETVTYTKDDLVTYSPITEKHVDTGMTLLEISEAAIRYSDNTAGNLLFNALGGP +DSLEKAMREIGDNVINADRTETNLNEAKPGDIRDTSTPKALATSLQAFALDDLLSESKQN +MLLEWLKTNTTGDTLIRAGVPEDWTVGDKSGAGGYGTRNDIGIVWPPNREPIVIAILSSR +DTEDAEYNDDLIKQATEITVN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar yosoo TaxID=180848 RepID=A0A243C5X2_BACTU +----DNSFAKLEKEYDAKLGIYALDTGTNQTV-SYQSDDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKTVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BEB8433 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAAGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. juglandis TaxID=195709 RepID=A0A383SCY1_XANCJ +--ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD +KGELTLAKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWRIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG +ATVDAAARDAALKAVAAAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. BRIP62418 TaxID=2182391 RepID=UPI000F8F399E +--ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD +KGELTLGKRVKIRAADMLEHAPITERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG +ATVDAAARDAALKAVAAAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuB4-4 TaxID=1053211 RepID=R8S1W6_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides (strain KBAB4) TaxID=315730 RepID=A9VGR9_BACMK +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYNSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKNPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=UPI000EFBBCBE +----EAQLATLEQSSGGRLGVFALNTADGKQI-GYRVDERFPFCSTFKVILIGAILARST +QVSGLLQQRIQYSQSDVVHYSAVTAQHVGDGMTVGELCVAAIQHSDNTAANLLIKLLGGP +QAVTAYARLTGNPVFRLDRMETSLNDAVPGDPRDTATPAAMARSLQTLTLGEALPVPQRT +QLLDWLRGNQMGSKRIGAALPAGWSMGDKTGTGDYGTANDLALIWPPSRPPILLAIYQTQ +REQDAKARDDVIAAAARIVL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2C4FP88_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK +VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGARNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A2Z4MDY8_BREBE +---MDLKFAALEKKFNARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP +--LEELDKVITYSKDDLVTYSPITEKHVATGMTLREVADAAVRFSDNTAGNLLFKELGGP +KGFESALRQIGDSVTTSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGDVLSSDKQT +ILIEWLQGNTTGDKLIRADVPKDWKVGDKTGAASYGTRNDIGVIWPPNKKPIVIAVLSSR +DKQDATYDDALIAEATKVAVD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001155981B +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IATLNEVITFTTEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNTTGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] Class A beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B0KJM5_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASIYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas euvesicatoria TaxID=456327 RepID=UPI000F8F7B16 +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRVD +QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP +AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTMPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 2BBP-J2 TaxID=2719381 RepID=UPI00143202A3 +------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP +--GARLDERIPYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAANLLLRDIGGP +RGLTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADHRALVLGDALPAAGRA +LLTDWLVRNTTGDRRIRAGAPRGWRVGDKTGSGDWGRGNDVAVLWPGGGPPLVLSVLTER +PDRAASPSDELVAEAARRVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=E5G517_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDPGGTELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. F-7 TaxID=573566 RepID=UPI000A98E004 +------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP +--GARLDERIPYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAANLLLRDIGGP +RGLTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADHRALVLGDALPAAGRA +LLTDWLVRNTTGDRRIRAGAPRGWRVGDKTGSGDWGRGNDVAVLWPGGGPPLVLSVLTER +PDRAASPSDELVAEAARRVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=UPI001316B3DD +--DLDETFATIESDYDARVGVYAIDTGSDETI-DYRSEERFAFASTYKALAAALVLKQNT +--MEELEEVITYTEDDLVSYSPITEKHVDTGMTLAELSEAAVRTSDNTAGNLLFEELGGP +EQFQQSLREIGDDVTQSDRYETALNEFTPGNTRDTSTPAALATSLQGFAVGDLLTDDKRE +RLLDWMQGNATGDTLIRAGATEGWTIADKSGAGRYGTRNDIAVVWPPDREPIILAIMTRH +DTEDAEYDDALIAEVAEATLN-- +>[subseq from] UPI001447CAB8 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI001447CAB8 +---LEKTVTGAESRLSARIGVAVLDTETGKTW-THRADERFPLNSTFKAFLCAALLEKGE +QGEVQPERRVKIRSQDLVSYSPVTEKKVGSGMTYLELCEAAVAISDNAAANLVLEAVGGP +AGLTDYLRGIGDTITRLDRTEPGLNEGRPGDARDTTTPAAAVATLQKLVLGDALSSTARV +QLTGWLLDNKVGNATLRAGLPEEWPVADKTGAGANGSRNNIGVIWPDDREPVVIAVYITQ +TDASFDDRNKAIADIAAALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Erwinia typographi TaxID=371042 RepID=A0A0A3YXT8_9GAMM +-pALRQQLASLEKQVNGRIGMALLDTDSGRTL-SYRGQERFAMCSTFKLLAASAILHRSQ +QQPGLLQKRLRWQAADAVPYMPITEKHLHDGMTLAGLCAAALQYSDNLAANLLLKELGGP +SAITRFTRLLGDTVTRLDRHEPELNTAIPGDPRDTTTPLNMIGNLHQLALGKGLKDREQQ +QLVRWLKGNTTGKKAILAGLPAGWVVGDKTGSGGYGTTNDVGVLWSPEGKTLVMAVYFTQ +HDKNASSRQDVLAQVASLT---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2J9BFQ0_BACTU +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYTSTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Methylibium sp. CF059 TaxID=1500261 RepID=UPI0006460178 +-----AHWKAIEDSARGRLGVAVLDTADGRID-GHRLDERFPMCSTFKWLAAAHVLQRVD +VQQEQLDRRIRFGREVLVPNSPVTSKAAGGDLTLAELCEATITVSDNAAGNLILQSYGGP +AALTRYARTLGDTKTRLDRWEPELNEARPGDPRDTTTPRAMTTALRATLVGDALSPAGRE +QLRRWMEATRTDVKRLRADLPEGWHLASKTGTGARGSTNNVGVFWPPGRPPIVVAVYLTE +AHAGEAARNAAVAQVARVVT--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=A0A4U8VXH4_9NOCA +------QFAELETTAGARLGVFAVDTGSERTV-AHREHERFPMASTFKGLACGALLREHP +LSTGYFDQVIRFSAAELVEYSPVTETRVESGMTVAELCHAAITVSDNTAGNQLLKLLGGP +QGFTAFLRSLGDNTSRLDRWETELNTAIPGDERDTTTPAALAADYRALVVGDVLGEPERA +LLTSWLVANTTGGTRIRAGLPADWTVGDKTGSPAYGSALDVAVAWPPGRAPIVIAVLTTK +SEQDAEPDNELVADATRAVV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A5Q2ZM04_BACIU +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKRNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=UPI001012019B +-aDTLSTVKQAETTLAARVGYAELDLASGKVLgSYRVNERFPMMSTFKVLLCGAVLARVD +AGQEQLDHRLRWQKTDLITYSPVTEKHLADGMTVAELCDAAITMSDNTAANVLLSTLGGP +QKLTAFLRKTGDAVTRLDRVEPELNEALPGDVRDTTTPEAMAKTLRQLLTGNTLSAASRQ +QLARWMEDDKVAGPLVRSVLPAGWYIADKTGAGERGSRGIVAALGPDGTPSRILVIYVTG +SSATMDERNKQIAAIGEAVIKQw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI000BF99398 +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +EKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase 3 n=1 Tax=Bacillus cereus TaxID=1396 RepID=BLA3_BACCE +----NHAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTRKDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH +DKEDAEYDDTLIADATKIVLE-- +>[subseq from] Beta-lactamase n=1 Tax=Ramlibacter sp. 18x22-1 TaxID=2530451 RepID=A0A4Z0BEK3_9BURK +-------WAAIEASARGRLGVAVMQ-ADGSVH-GHRLDERFPMCSTFKWLAAAHVLRRVD +RGQERLDRRIRYGREVLKPHSPITRQQVGEGMTLGELCHATITVSDNAAANLILGTFGGP +QGLTRFARGLGDKATRLDRWEPELNEARPGDPRDTTSPRAMAGLLHATLVGDALSPRSRE +QLAAWLQATTTNGQRLRADLPAGWRMGSKTGTGARGTTNDAGIFWPPGRPPVIVAVYLTQ +SDAPEAARNGAAAQVARWVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella genomosp. 9 TaxID=1416803 RepID=UPI000A3222C6 +--DFHAACARLERAHDRRLGLYAIDTGNGRTV-GYRAGERFAFCSTFKALLAGAMLARLK +ADAGILDRRILYTRHDLVPYSPITEKHAGGSMTVADLCAAALQYSDNTAANLLLHAVGGP +AALTGYARALGNRSFRLDRYEPALNSAIPGDPRDTVTPADMAASLRTLAVGNALTAGGRE +RLREWLLGNTTGANRIQAGAPAGWRVGDKTGTGDYGAANDIAIVLAPDRPPIVLAVYTAA +SATDAAADEPLIAAATQLAI--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2C4PWK0_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAMGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8XP18_BACCE +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-SYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWDVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. WMMA2032 TaxID=2039870 RepID=A0A2D1I4E3_9ACTN +----DRAFRQLEETFDARLGVYAIDTGTGTTV-GYRADERFAYASTFKALAAAEVLDETT +--DAELDRVVRYSADDLVTYSPITEKHVADGMTLRALADAAVRYSDNTAGNLLLRRLGGP +QRFEKELRGVGDKVTAPARYETALNEARPGDRRDTSTARALAQDLRAYAVGDSLDPADRD +ILNGWLRGNTTGGELIRAGVPDGWVVGDKTGSGGYGTRNDIAVVWPPDRAPIVLAVLSSR +DQKDADYDNALIARAAEVAI--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B0XLN8_BACCE +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-SYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWDVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus siamensis TaxID=659243 RepID=A0A268DWS5_9BACI +---TNKKFVQLEKKFDAKLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNDIIRYTKDDLVTYSPITEKHLDTGMRLKEISEAAVRYSDNTAGNLLLQQLGGP +TGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRM +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALISEAAKAALD-- +>[subseq from] Beta-lactamase n=1 Tax=bacterium enrichment culture clone F7(2012) TaxID=1155062 RepID=H9AZ20_9BACT +-tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYQPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPALNEVNPGETQDTSTARALATSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAGSYGTRNDIAVIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVIK-- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus antibioticus TaxID=2570228 RepID=A0A4U2Y9Q5_9BACL +--AMDQKFAALENKFDARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAILHQKP +--LEELEKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP +KGFESALRQMGDLVTTSERYETELNEAKPEDIRDTSTPKALATSLRTYTVGDVLSSDKQK +ILIEWLQGNTTGAKLIRSGVPKGWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR +DKQDATYDDVLIAEATRIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora deserti TaxID=2070366 RepID=A0A2W2DN53_9ACTN +-----PRFGQLEAEFGARLGVYAVDTGSGRTV-EHRADERFGYASTFKALAAAAVLDETT +--TAELDQVVRYTAADLVDYSPITKDRVGSGITLREAADAAVRYSDNTAANLLLDRLGGP +AGFEKALRELGDQVTDPERRETALNDVAPGETRDSTTPRAFATDLRAYVVGDALSAEDRD +VLVDWLRRNTTGDKLIRAGVPAGWTVGDKTGGGPYGIRNDIAVVWPPDGAPIVLAILSSR +TEKDDEYEDALIAEAAKATI--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=C2XUB5_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDD0967 +-dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD +KGDESLDRRVTYGKDKLATYSPETEKHAGGDMTMAEICKAGITLSDNTAGNLMLESFGGP +AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN +QLVDWMIANTTGGARLRAGLPSDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYMAE +TTVKMDEFNPVFAEIGKMITE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFB2455 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREELVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF98880 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREELVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q8GEA5_KLEOX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNR------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8GEA6_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNR------------- +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacter rhizosphaerae TaxID=2010972 RepID=UPI0013D763B9 +-----RGMAALEARSGGRLGVAVLDTADGRTF-AYRGDERFAMCSTFKALVAGLVLKRVD +QGQERLDRRIVYGRNVLLAHSPATEQHINDGMTVGALCEATVTLSDNAAANILLYTFGGP +PALTAFLRGLGDKVTRLDGYEPNLNVVRPGEIHDTTSPNAMLGALRALALGPVLSSASRQ +QLVAWLVANQTGDKRLRAGLPAGWKVGDKTGSWGDGTTNDIAVIWPPGRPPLLITAYLSR +STLADDGRNAVIAEVARLVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=UPI00091C1D11 +--TAQTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSA +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMNVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDTWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLIIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=Q84HU2_ECOLX +--ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNR------------- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDBC3C5 +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD +QGMEKLDRRVTYGKDKVVTYSPATEKHADTDMTVGELCGAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAAKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGNNRLRAGLPKEWKTGDKTGTGNNGSYADIAVIWPPDRGPVLVTTFVAD +ATAPAKDVETVFAEIGKIVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0012FB5050 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKTLATSLQAFTLGDILSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C2IAW6_BACCE +----NDSFAKLEKEYDAKLGIYALDTGTNQTV-SYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTHSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWDVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora krabiensis TaxID=307121 RepID=A0A1C3MWW4_9ACTN +---HDREFRLLEERFDARLGVYAIDTGTERTV-AYRADERFAYASTFKALAAAEVLDETT +--DAELNRVVRYSADDLVTYSPITQQHVADGMTLREIADAAVRYSDNTAGNLLLRQLGGP +QRFEKKLRAIGDTVTDPARYETALNEARPGDRRDTSTARALAQDLRAYAVGDALAPADRD +VLTGWLRGNTTGGELIRAGVPDGWAVGDKTGAGGYGTRNDIAVIWPPDRAPIVLAVLSGR +DEKDADYDNALIARATEVVIS-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A242ZDL2_9BACI +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNP +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=6 Tax=Bacillus cereus TaxID=1396 RepID=R8KHX3_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAAGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFB336D +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKTS +--IEDLDQIIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILVILSNH +AKEDAKYNDKLIANATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFDDF07 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEVLDQRITYTNEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=A0A0B7G5U6_KLEVA +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPVVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTHLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus sp. 3H-10 TaxID=2672567 RepID=A0A6B3VUN7_9BACI +--SASREFADLESKFDARLGVYAIDTGTNRTV-SYRPNERFAYASTYKALAAGALLQHYS +--IDQLDELVTYTSEDIVTYSPVTQLHVDTGMTLREVIEAAVRYSDNTAGNLLLEKLGGP +EGFETALRQIGDNITQVDRYETDLNSAIPGDKRDTSTPKALATSLKAFAVSDLLPTEKRM +ILTDWMRGNTTGDALIRAGAPKGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR +DTQNATYDNTLISEATKVALN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0010BD627A +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSK +DEKEAIYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0012988F66 +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH +DKEDAEYDDTLIADATKIVLE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A168D6V1_BACCE +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH +DKEDAEYDDTLIADATKIVLE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus siamensis TaxID=659243 RepID=UPI0012DF227F +---TNKKFVQLEKKFDARLGVYAIDTGANKTI-AYRPNDRFAYASTYKVLAAAAVLKTSS +--NEKLNDIIRYTKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYHNALISEAAKAALD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1G7DA42_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI001144274D +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNMLFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=environmental samples TaxID=48479 RepID=X2KZE3_9BACT +----NKKLVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKIVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI00087203BB +-----DSFVKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00119F7C1B +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKVLRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00114598E4 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIIFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=C2X4Y9_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVLVK-- +>[subseq from] Beta-lactamase n=5 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2T7YL80_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSK +DEKEAIYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9E539_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000A27C80B +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNP +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009B6A35D +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVFN-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobacter gummiphilus TaxID=946333 RepID=A0A1W6L688_9BURK +-----SGLADLERTVGGRLGVAVLDSATGGLT-GRRLDERFPMCSTFKWLAAAKVLQRVD +AGEESLERQLPVSAADILDHSPTTGKHVGGSLSLGELCDATIALSDNAAANLILATYGGP +AAVTAFARSAGDPATRLDRTEPALNESREGDPRDTTTPAAMARTLRAVLLGDVLKPASRQ +QLTAWMLGTQTSGERLRKDLPAGWRLADKTGTGSNGSANDVGVFWPPGRPPVVVAVYLTG +GKAPLERRNAVIATVAA------ +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0010517BA5 +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN +ILTGWMKGNATGDKLIRAGLPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEVTYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000627825C +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKIVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0002F74658 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKIVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI001009ADA4 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKIVLN-- +>[subseq from] Beta-lactamase n=2 Tax=Xanthomonas perforans TaxID=442694 RepID=A0A0G9F3Z5_9XANT +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRVD +QGKLTLAQQVRIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP +AGVTAFLRGIGDAQTRTDRYEPQMNRFADDDPRDTTTPAAMAATLRTLLLGDALHPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FD89_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KEPTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A381KS28_BACCE +----NHAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTRKDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH +DKEDAEYDDTLIADATKIVLE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A410YSW5_BACIU +----NKKLVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF32896 +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLKKKS +--IEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLIEIGDTVTNPERFEPELNEVHPGETHDTSTPKALATSLQAFALGDVLSTEKRD +LLKDWMKKNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5KN16_9BACT +--EFENRVATIEARTGGRIGVAALDTASSKHL-DCRSEERFPMCSTFKFLAAAAVLKRVD +EKQEKLDRFVPYDAKDILEYAPVTKIHLKEGMTLGALCAAAIEQSDNTAGNLLLDAIGGP +IGLTNFARTIGDKVTRLDRKEPELNSAIADDERDTTTPAAMLADMLQLLLGNTLSPSSRH +QLEQWLQANQTGASMIRAGIPTSWIIGDKTGRGANGATNDIAIMRPPGRAPILLVIYSAG +STATANDHAAVLAEAAKIVI--- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora inaquosa TaxID=2203716 RepID=A0A3N9WTW2_9ACTN +----DHEFRQLEERFDARLGVYAIDTGTGRTV-QYRADERFAYTSTIKALAAAEILDETT +--DAELDRVVRYSADDLVTYSPITEQHVGDGMTLREIADAAVRYSDNTAGNLMVRQLGGP +QKFEKELREVGDKVTDPARYETALNEAKPGDRRDTSTPRALAQDLRAYAVGDALEPADRD +ILNEWLQGNTTGGELIRAGVPDGWVVGDKTGAGGYGTRNDIAVICPPDRAPIVLAVLSSR +DQKDASYDNALIAEATKVVMAGw +>[subseq from] Beta-lactamase n=1 Tax=Roseomonas sp. Z24 TaxID=2382222 RepID=A0A3A9JG65_9PROT +----PAAFAQIEAARGGRLGVAVLDTGSGQGT-GYRQDERFPLASTFKLLAAAAVLARVD +AGQDNLDRRIRFKREDLVTYSPTTGQHAGADMTLAEIAGAAVTLSDNTAGNLLLNVLGGP +AGLTAWLRQQGDAVSRLDRMETDLNEASPGDPRDTTSPAAMLRHLQAVTLGDALSPASRA +RLRGWMRASSTGDNCLKARLPQGWVVEDKTGSGGNGTRNDVALLWPPGGAPMLVAAYLTG +GASEIAARDAVLADVGAAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodobacterales bacterium TaxID=1948890 RepID=A0A5D0VBW8_9RHOB +---LEAAVAEAEGSLHARIGVSVIDTETGATW-SHKGGERFPMNSTFKSFLCAALLDAAQ +KEEADLSRSVTIEESDIVRYSPVTEKRVGGSFTLEQLCETTVTYSDNAAANIVLEEIGGP +EGLTAYLRSIGDTVTRSDRPEPDSNSGIPGDPRDTTTPDAAAETLRKTVLADALSKPDRR +KLASWLVDNKVGDKTLRAGLPKDWVIADKTGAGANGSRNDIGVIWPEGRKPVVIAVYITQ +TKAAFDDRNKAIADIAAALVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas citri TaxID=346 RepID=UPI000247CB7E +--MLRAQWAQIEHGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A410R118_9BACI +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0006182C6C +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0J7D281_BACCE +----NNSFAKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLLQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGNALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000D883779 +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFKKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVEWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. UNC437CL72CviS29 TaxID=1340430 RepID=UPI0009E0A8BC +--ATHQKYAQLEKKFDARLGIYAIDTGTNRTV-SYKQNERFAFASTYKALAAGALLMQNP +--IDKLNEVIIYTKDDLVEYSPITEKYVDTGMTLGEIAEAAVRYSDNTAGNLLFKELGGP +EGFETALKQIGDRVTQADRFETDLNEAIPGDIRDTSTAKALATDLKAFTAGNALPADKRK +ILTDWMHGNATGDKLIRAGVPKDWEVADKSGAGSYGTRNDIAIVWPPNREPIIIAILSSR +DTKDATYDNELIAQAATITIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0007C1B4CD +----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLESALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYSDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=9 Tax=Bacteria TaxID=2 RepID=A0A089NF48_9BACT +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEGLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPEHFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKKNTTGDSLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIALD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKJ3_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRTHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAADLLLATIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDRMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIG------- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacteraceae bacterium DB1506 TaxID=2230885 RepID=A0A327ML67_9PROT +---LPAALQRIERESGGRLGFVMLESGSGGGA-AHRPAERFPMCSTFKLLAAAAVLARVD +AGQERLERRVRFGRAALVPYSPITEQQAEGEMTLAALAAAAIGYSDNTAGNLLLEAIGGP +AGLTGFARGLGDAVTRLDRIEPALNEALPGDPRDTTSPMAMLTDLRRLLLGDALSAAGRE +RLTGWLLGSRTGDSRIRAGLPAGWRFGDKTGSGERGTTNDVGIVWPPGRPPVLFAAFLTE +TEAGMEQRNATLAAVGRAMA--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF61D08 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNTTGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVAIN-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A519EWU2_PSESP +--AIAQQLAELERRHGGRLGVAMLDTSSQRLI-SHRGDERFALCSTFKCLAAACVLARVD +QKHEDLSRRIVYSAEQLVAYSPTTELHAGGQLSVGSLCEAAMTLSDNTAANLLLDSVGGP +EGLTAWLRSMGDTQTRLDRREPELNENRPDDLRDTTTPVAMLQTLNTLVLGEKLTPASRD +QLTAWLVNNQTGDKKLRAGVPVSWRVGDKTGSGANNASNDVAVIWPGERGLMLVTAYYTG +SRASGDQINALMADIGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000893B095 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGVTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 2323.1 TaxID=1938841 RepID=A0A286HYA7_9ACTN +--DAHAALRRLERANRARVGAYAHNTVTGATV-AYRADTRVPLCSVFKTLAGGAVLRDLD +HHGETLARRVHYTDADLVANSPVTSKHLATGMTIAELCAAALQRSDNTAANLLLRALGGP +TAVTAFARSLGDRTTRLDRWEPDLNSAEPWRTTDTTTPAAIARTYTRLLLGDALTPADRA +RLTAWMKANETNTDRFRAGLPRDWTLADKTGTGSYGTGNDVGVAWTPDGTPIVLAVLTGK +AQQAATPDDPLVADVTRVLAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Deltaproteobacteria bacterium ADurb.Bin207 TaxID=1852869 RepID=A0A1V5X6S5_9DELT +---REAAWESIETTSGGRLGVAIFDSANGAWT-GHRIDERFPMCSTFKWLAAAYVLHRVD +RGQEKLDRRIRYGSDALLPWSPETEKHADGSMTVAELCEAAIAMSDNTAANLILKALGGP +SALTHFLRTQGDTVTRLDRWEPDVNTSIPGDGRDTSSPRAMATLLRRWVLEPTLSDGSRE +RLVQWLRSTKTNTHRLAAGLPTGWKLGSKTGTGPYGTTNDVGVYWPMGRAPIVAAVFLTE +SEKSQENREDALARVARMVF--- +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillaceae bacterium GAS479 TaxID=1882832 RepID=A0A1H2B6C0_9BACL +--AFRRSFVQLEEKYGARLGVYAIETGTGRSI-AHRPDERFAYASTYKALAAGFVLKHST +--ANELERVITYSKDDLVSYSPVTELHVNTGMTLKQLCEAAVRYSDNTAGNLLFKQLGGP +KGYEVALREIGDVVTQVDRLEPELNEAVPDDTRDTSTPRALATILSNFTVGDVLADDKRS +ILMDWMSGNATGDELIRAGVSEDWKVADKSGAGSYGTRNDIAVVWPPSGAPVVIVIMSSR +DEQNADYDNALIAEAAKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF28D57 +-------FVKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas citri pv. phaseoli var. fuscans TaxID=473423 RepID=A0A2D2RTB1_XANCI +--MLRARWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD +QGKLTLARQVKIHASDMLEHAPVTERHVGGSLSIGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGVGDAQTRTDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGGPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BEE4CA7 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELGDASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A151UPR3_BACCE +-qATHKEFSQLEKKFDAQLGVYAIDTGTNETI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPITEKHIDTGMTLGEVAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPDDKRK +VLTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKGATYDNQLIKEAAEVVID-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0008FDCEE7 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNIIFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKATATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. COPE52 TaxID=2233998 RepID=A0A345X4C1_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SAFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar pirenaica TaxID=180863 RepID=A0A243JLZ7_BACTU +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDGRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0A7HFD6_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRESCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Proteus hauseri TaxID=183417 RepID=A0A410XDR0_PROHU +--AIEQQLAALEKSSQGRLGVALINTTDNSQI-IYRGNERFAMASTSKVMAVAALLKESE +QKADLLDKNISIKQSDLVAYSPIVEKHLTTGMTLAQLSAATLQYSDNTAMNKILAHLGGP +EKVTQFARSINDITYRLDRSEPELNTAIHGDPRDTTSPLAMATSLQTLTLGDALGQYQRN +QLITWLKGNTTGDNSIKAGLPKQWIVGDKTGSGDYGTTNDIAVIWRENQAPLILVIYFTQ +QEKNAKPRKDIIVKATEIVTKPf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus Rock4-18 TaxID=526988 RepID=A0A2I0RBJ7_BACCE +----NHSLVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTNKDFVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIENRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces atriruber TaxID=545121 RepID=UPI0006E3D9C8 +---TLRRLRALEDAYPGRIGVHALHTGTGAVV-AYRADERFAIASTFKVLAAAAILRRAR +EEPGLLDVLIRYGRDDLVAHSPRTEMHLETGMTVRELCDATITYSDNAAANLLMRRIGGP +SGITEFARSLGDPHTRLDRWETDLNTNIPGDRRDTTTPASMTANLRKLVLGKALHPLDRG +QLTRWLLENTTGDKRIRAGLPKEWRVGDKTGSPAYGGVNDVAVAWPPKRAPLVISVYTTR +LDPDTPGEDRIAQDITRIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Motiliproteus sp. MSK22-1 TaxID=1897630 RepID=A0A1R1MHV2_9GAMM +-eEFQKKIAAIESKLDGRIGVAILNLHSGDKW-TYKADSRFPVSSTFKVQLCGAILAKVD +AGKESLNRPITFKKSEIVSWSPITEKRVQTGMSVGELCEATITMSDNTAANLLLDMIGGP +QGLTMFLRKIGDDITRLDRWETKLNEGVPGDLRDTTTPTAALGTLEKLLFGKVLSMSSRK +QLTDWMINDKVADDLLRTSLPEGWKIGDKSGAGGYGSRSIIAFIMPPNKGPTLVTIYLTE +NEVDFSTRNRMIAEIGRLIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2B3X6S7_BACTU +-------FVKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI00084A1D41 +-----QKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKAYRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDADYHNALIAEAAKVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. HM5-17 TaxID=2487710 RepID=A0A3N2P9B2_9ACTN +----SPEFGRLESRFDARLGVYAVDTGTGRTV-EYRADERFGYASTFKALAAAALLDATT +--SAELDRVVRYTEADLLAHAPITRQRVRTGMTLRELAEAAVRYSDNTAANLILDRLGGP +DGFERALRDLGDRVTNPERREPGLNDVRPGDTRDTSSPRALATDLRAYVLGDALAAEDRD +LLVDWLRRNTTGDRLIRAGVPAGWTVGDKTGSGSYGTRNDIAVVWPPDGAPIVLAVMSRR +DERHATYDDALIAAATRAVI--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. FBKL.4005 TaxID=2015515 RepID=A0A255PB99_9ACTN +----RAELAELERRYGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDRA +-GCAPLDRVVHYPPHDLLPNSPRTEENVATGMTVADLCAAAIQYSDNAAGNLLLREVGGP +AGLTRFYRSLGDEVSRLDRWEPELNAAIPGDARDTTTPEAIAESLERLTLGRALAGADRE +RFVGWLKGNRTSDERFRKGLPKDWTVADKTGTGDYASAHDIGVAWTTRGTPVVLAVLSSK +STPDAPVDQALIADAAAVVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax guangxiensis TaxID=1775474 RepID=A0A502DYB0_9BURK +--DLHLRLRQIETESGGRLGVCILNTADGRRF-GHRMDERFPMCSTFKLLAAALVLQRVD +SGQEMLGRPIAIERSAIVPHSPLTEPNVGGTMTMGALCEATITQSDNAAANLMLASFGGP +GGLTAYVRSLGDPSTRLDRNEPSLNEAIAGDPRDTTTPAAMLGLIQTLLLGTALKPASRD +QLRNWLLANKTGDARLRARLPAGWRVGDKTGAGAFGTNNDVGIVWPPGRAPILVTAYLTQ +TQAPLDRRNAALAAVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. CF258 TaxID=1500300 RepID=UPI00055C858E +-nDIEKQLAALEKRTGGRLGVFVLDTSTNVSF-GRRQDERFAMCSTFKALAAAFALARAD +KGEEKLDRRIPVLKKDLLSYSPVVEKHVGGGMTVRELCDAAVTYSDNAAANLLLASFGGP +KGLTTWLRSIGDETTRLDRTEPELNEAKIGDPRDTTTPMAMTETLGRLLLQDVLSPSSRD +QFTAWLVANTTGDRRLRAGLPQDWMIGEKTGTSGRGEAGDIGFMRPREGHTILASVYIAE +GKKPTKELEPLFAEVGKLIA--- +>[subseq from] Beta-lactamase n=2 Tax=Salinisphaera shabanensis TaxID=180542 RepID=U2G169_9GAMM +--DFAATMHKLEKRHGGRLGVCVLDTGSDRYI-AQRGDERFLLCSTFKVVAAAMILSRVD +AGEESLDRHIDYATADLVTYSPETEKHAGTGMTLGAICRAAITLSDNTAGNLMLQSLGGP +KALTAFMRSLGDDVTRLDRYETALNEYTPGNPHDSTTPRAMVGLMQKILLGDRLTSSSRD +QLIARLEANETGDNRLRAGLSESWRIGDKTGSGGNNTANDIAITWPEGGAPVLIATYYTG +SSASKAQRDRVLADVGAVAA--- +>[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI000BAC5108 +-------------------GMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLEWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=5 Tax=Xanthomonas TaxID=338 RepID=Q8PHT7_XANAC +--MLRAQWAQIEHGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A136C6T7_BACCE +-qATHKEFSQLEKKFDAQLGVYAIDTGTNETI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPITEKHIDPGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPDDKRK +VLTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A519ENW9_9BURK +--DLHLRLRQIETESGGRLGVCILNTADGRRF-GHRMDERFPMCSTFKLLAAALVLQRVD +SGQEMLGRPIAIERSAIVPHSPLTEPNVGGTMTMGALCEATITQSDNAAANLMLASFGGP +GGLTAYVRSLGDPSTRLDRNEPSLNEAIAGDPRDTTTPAAMLGLIQTLLLGTALKPASRD +QLRNWLLANKTGDARLRARLPAGWRVGDKTGAGAFGTNNDVGIVWPPGRAPILVTAYLTQ +TQAPLDRRNAALAAVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. JAB6 TaxID=2127050 RepID=A0A2T3ECY1_9RHIZ +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD +QGAEKLDRRITYGKDKVVTYSPETEKHAGGDMTIAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAAKGDPRDTTTPDAMLDSIGLLTLGNTLSDTSRE +QLVNWLVANTTGNNRLRADLPKEWKVGDKTGTGNNGSYADIAVIWPRDRGAILVATFVAE +ATAPAKDVEAVFAEIGKIVV--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2A7D7A4_BACAN +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHSDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Uncharacterized protein n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A1G0HAN5_9GAMM +---INEKFKNLETSLEGRIGLYAINTANNQSI-QYRALERFPIQSTFKVMAVSAILKQSE +ADNNLLKLKITYTKQDLVFWSPITEKYVDDGMTIFDLCAAAMMYSDNTATNLIVKKSGGP +EAVTAFARSIGDNTFRIDDWEPDLNSN-PNDLRDTSTPKAMEKSLQKLTLGDVLTSSKRN +QLVTWMKGNTTGDTRIRAGVPKGWIVADKTGAGDYGISNDIGIIWPPNCAPIVIAIYFGH +NKKDTTRRDDILASSTQLVINEf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. 18055 TaxID=2681403 RepID=UPI00135B9B91 +--EIDRRIGALEKQIGGRIGVSVIDTQTNISF-GYRETESFPMFSTFKVLAAAMVLVRVD +KGEENLERRIVYDRSQIVGYSPETEKHVAGEMSVGELCKAAITQSDNTAANLLLESLGGP +KELTNWLRTLGDGSTRLDRIEPDVNEARKDDPRDTTTPDAMLDTLGNLTLGSVLSEPSQN +RLVEWMVANTTGNERLRTGLPDSWKIGDKTGTGKSGAAADIAIAWPPGHGPILIAVYVAD +ATVPTAEINPVFGEVGRIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1W6A8Z9_BACMY +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKSLAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIMLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. malvacearum TaxID=86040 RepID=A0A221MSD1_XANCM +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG +AKVNDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus novalis TaxID=220687 RepID=UPI000825F18B +--QLHREFAELENKYDARLGVYAIDTGTNRKV-SYRPQERFAYASTYKALAAGALLQHYS +--IDQLDELVTYNSEDLVSYSPVTQLHVDTGMTLREVAEAAVRYSDNTAGNLLLEKLGGP +EGFETALRKIGDNKTQADRYETDLNSAVPGDTRDTSTPKALATSLQAFAVSDLLPTEKRT +ILTDWMRGNATGDALIRAGAPTGWEVDDKSGAGSYGTRNDIAVVWPPNRAPIVIAVLSSR +DTQNATYDNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A3D5TSG0_BACSP +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHIGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A6D1UUW2_BACCE +-qATHKEFSQLEKKFDARLGVDAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas citri pv. fuscans TaxID=366649 RepID=A0A2H1SN20_XANCI +--MLRARWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVKIHASDMLEHAPVSERHVGGSLSIGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGGPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces olivoreticuli TaxID=68246 RepID=UPI000E23E847 +-dALTERLKELEREHSARLGVYARDTATGRTV-LYRADERFPMCSTFKTLLAAAVLRDLD +HHGEFLAKRIRYTKKDTDAYAPVTGKNLRHGMTVSQLCSATVSYSDNAAANLLLHELGGP +NAITRFCRSTGDGTTRLDRWEPDLNSAEPERRTDTTTPRAIGQTYARLTLGDALDPKDRK +RLTGWLLANTTSAERFRAGLPADWTLADKTGAGKYGTNNDVGITWPPHRPPIVLSVLTTK +HDREAAADNPLIARTAALVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0J7GT95_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F6D5_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKILLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000B433A0E +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP +KGYEKALRQMGDRVTLADRFEPELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNTTGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. Root487D2Y TaxID=1736547 RepID=UPI000700A504 +------GIVALEARGGGRLGVSVLDTADGKTF-AYRGDERFAMCSTFKALVAGLVLRRVD +QGLERLDRRIVYGKSVLLAHSPATEKHVGEGMTVGALCEATVTLSDNAAANVLLYTFGGP +PALTAFLRGLGDKVTRLDGYEPELNVVRPGEIHDTTSPNAMLATLRALTLGSTLSPASRR +QLIAWLVANQTGDARLRAGLPAGWKVGDKTGSWGIGTTNDIAVIWPPGRSPLLITAYLSR +STLGNDGRNAVIAEVARLVT--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B585C2 +-qATHKEFSQLEKKFDAQLGVYAIDTGTNETI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPITEKHIDPGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPDDKRK +VLTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF54033 +----SQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAAGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000EA227A3 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +NGYEKALRMMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Siccirubricoccus sp. 1-3 TaxID=2595053 RepID=UPI0011F0E139 +------PLAALEARHGGRLGVAALDTGSGRAL-AHRADERFPLTSTFKFLAAALVLARVD +AGEERLDRHLAYGESALVPYSPVTGPAAARGLTMAEACDAAVTLSDNTAGNLMLDSFGGP +AGLTAWLRRIGDAETRLDRRETELNEAAPGDKRDTTTPAAMLATMRTLLLGEVLSPTSRA +RLLAWLEGCRTGDRRLRAGFPAGWRLGDKTGSGGRNSTNDVAIAFPPGRAPLLVAAYYIG +ADVPMAEREAVLAEVGRLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Alsobacter sp. SH9 TaxID=2109933 RepID=A0A2T1HZ82_9RHIZ +---LVATIREVEARLGARVGASVFEVGSGRRW-SHRAEERFPIASTFKAFACAALLARVD +GGQKRLGDEVAIRSSDLVTYSPVVEKHVGGAMTLGDLCAAATALSDNAAGNLILDNIGGP +AGLTAFMRGIGDEATRLDRRETELNEAAPGDPRDTTTPAAAADSLRKLLLGDVLSPKSRR +QLQDWLVANQVGGPLLRASLPQGWRIADRTGAGGRGTRNVLAAIWPPGREPVCAAIYLTG +TEASMDARNAAIAEIGRTLV--- +>[subseq from] Beta-lactamase n=1 Tax=Rubrivivax benzoatilyticus JA2 = ATCC BAA-35 TaxID=987059 RepID=F3LTI8_9BURK +------AFGAIERSVAGRLGVCAYDLETGRSL-GHRQDERFAMCSTFKWLLAAAVLARVD +RGQERLERRIVFGREALLEYAPTTSRHAGGAMTVAELCEAALTLSDNTAANLLLDTLGGP +GGLTAWVRTLGDRTTRLDRREPDLNEARPGDERDTTTPAAMVLALRQAVFGGALSRRGGD +LLLQWMTASTTGLKRLRAGFPPDWRVADKTGTGAQGTTHDVAVVWAPGRAPLLLAAYLTE +SQAPIEAREAALARVAAR----- +>[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus sp. 160 TaxID=2052660 RepID=A0A345PLP5_9BACI +--TINNDFAKLEDEFDATLGVFALETGTNQRV-TYRPDERFAYTSTHKALAVGALLQQNS +--VEDLNQRITYTQDDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP +SGFKKALHEIGDDVTNPVRMEPELNEVHPGETHDTSTPRALATSLQTFTLGDVLPTEKRE +LLIDWMKRNTTGDTLIRAGVPEGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAILSKR +DAKDATYDDKLVEQATKVVLK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. H1a TaxID=1397276 RepID=UPI000468452C +---SNQSFAKLEKEYGAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. PDC80 TaxID=1882827 RepID=A0A1I5JF52_9BURK +--DAEARLAALERDCGGRLGVHALDTGSGARI-AHRGNELFPMCSTFKLMLAAAILQRGT +AEPALLERRLSYTRAHLLPNSPITEKHLAEGMTVAELCAATLQYSDNAAANLLMHQLGGP +AGVTAYARSIGDTVFRLDRWETELNSAIPGDPRDTTSPAAMAASVQRLVLGDALGAPQRA +RLDGWLRGNTTSKERFLAGVPAGWAVGDKTGAGDYGTNNDVGVLWPASGAPLVLAVYLTF +PGKGAKTRNDVVASAVRIVAN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2T0EYP1_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKTLRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Massilia sp. Root1485 TaxID=1736472 RepID=A0A0Q7XUP5_9BURK +--DATQALAGLERRAGGRLGVAAWRRGGADVI-AWRGDERFPFCSTAKVMVVGTVLTLAA +RTPGLLDERVRYKKADLVSWSPVTEQHVDDGMTIADLCAAALQVSDNSACNLLLDRIGGP +AAVTAFARRIGDTAFRLDRRETELNAAIPGDPRDTTSPRAMARSLEALLLEEALAPDARR +RLLDWMLANTTGKERIQAGFPADCRVADKTGTGAHGTTNDVGLVFPPQGQPVIVAVYYTG +SKSD----SKVVADAAAIVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2B3KP92_BACTU +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLESFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH +DKEDAEYDDTLIADATKIVLE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. BPN334 TaxID=2217815 RepID=UPI0011EE4E1B +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWDVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar sinensis TaxID=1042875 RepID=A0A243MN57_BACTU +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWDVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF54B87 +----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELVDASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQDYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A4R4AYT1_BACTU +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTPEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Catenuloplanes japonicus TaxID=33876 RepID=UPI000A10F1CE +------VYQQLERRYDARLGVYAVDTGSGRTV-TFRGDERFAYASTFKALAAAAVLDRIS +--DADLHRVVHYTRADLVDYSPVTELHVDEGLTVGAIAEAAITVSDNTAGNLLFRELGGP +DGLERALRAIGDRTTSADRIETELNTAIPGDRRDTSTPRALATGLRAYTLGRELCATDRQ +QLITWLRANTTGAATIRAGVPDGWIVGDKTGAGGYGTRNDIAVLWPPSGAPIVIAVMSTR +DTPDATYDNALLADAAEAVV--- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterococcus faecium TaxID=1352 RepID=UPI00143337B5 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDA---------------- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF3620E +-qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNA +--MDKLNEVIKFTKEDLVEYSPVTERHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEQALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI00128BF473 +-tEMKDDFSKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALATSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPEGWEVADKTGAASYGTRNDIAIIWPPKGDPVVIAVLSSR +DKKDAKYDDKLIAEATKVVMK-- +>[subseq from] class A beta-lactamase n=2 Tax=Virgibacillus halodenitrificans TaxID=1482 RepID=UPI0002D3AAA2 +----DEKFAEIEKEYNARLGVYAIDTGANQRL-QYNPDDRFAYASTFKVLASAILLKQNS +--IEDLERVVTFSKDDLVTYSPVTEKHVDTGMTLGEISEAAIRYSDNTAANLLLEELGGP +EQFKQALRDLGDDVTQPERFETELNDFAPGKKRDTSTPKAMANTLKKVALDDFLPDDKRE +LLHNWMKGNATGDKLIRAGAPAEWVVGDKSGAGSYGTRNDIAIVWPPDREPIVIAVMSRH +EEEDAEYDDALIAKAAEIALN-- +>[subseq from] Beta-lactamase n=1 Tax=Aphanothece cf. minutissima CCALA 015 TaxID=2107695 RepID=A0A2T1F1V2_9CHRO +--AAEAGLAALEARSGGRLGVFAIDTASGARI-GHRAGERFPLCSTFKAILAGAVLHRSQ +RQPGFLEQRIRFGRQDLVSHSPIAEQHLEGGLTVEEMAAATVQTSDNTAANQLMARLGGP +AGLTAFARSIGNRTFRLDRWETALNSAIPGDPRDTDTPAGMGTSLQALVLGTALGPPQRQ +RLQDWLIGTTTGDRRVRAGVPSGWQVGDKTGTCGYGTANDVAVLWPPDRAPIVLAVFHTQ +ADPAAAAQDGVIAEAATIVAGAf +>[subseq from] class A beta-lactamase n=1 Tax=Halobacillus sp. Marseille-Q1234 TaxID=2686092 RepID=UPI0013D3FFE6 +--KTDEKFSKLENEFDAQLGVYALDTGTDQTI-EYQSEERFAFASTYKALAAAIVLQQKS +--KDELEEVITYTEDDLVTYSPVTKKHVDTGMTLLELSEAAVRTSDNTAGNLLFKALGGP +NEFEQALRQIGDNVTQADRIEPDLNEFTPGDTRDTSTPKALATSLKEFAVGDLLSNDKRE +LFTDWLKGNATGDALIRAGAPEGWVVGDKSGAASYGTRNDIAVVWPPNREPIVIAIMSHR +DQEDAQYNDELIAQAAEIALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF75003 +-----DSFVKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIILAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=C2R8E3_BACCE +-qETYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhizobium lusitanum TaxID=293958 RepID=A0A1C3U0P5_9RHIZ +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GYREEERFPLCSTYKALAVGFALTRVD +QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCGAAITLSDNTAGNLLLQSFGGP +AALTSWLRSTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLINWLVGNTTGDNRLRAGLPKEWKVGDKTGTGNNGSFADIAVVWPPDRGPILVTTFVAE +GTAPAKDIEAVFADVGKIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A4R4BK38_BACTU +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN +ILTGWMKGNATGDKLIRAGLPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEVTYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus subtilis TaxID=1423 RepID=A0A5F2KNH9_BACIU +----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNP +--IEKLNEVMHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALASDLKAFTVDNTLTTDQRT +ILTDWMRGNATGDELIRAGAPTGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0005C9B5B8 +----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNP +--IEKLNEVMHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALASDLKAFTVDNTLTTDQRT +ILTDWMRGNATGDELIRAGAPTGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. FMQ74 TaxID=1913579 RepID=A0A1J5X4Q9_9BACI +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTNAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI001145FF19 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDA28B4 +-dDVDQQLAALEKRTGGRLGVSVMDTGTNVSF-SNRETERFPLLSTFKVLASGMVLARVD +KGEENLERRVTYDQDKIVTYSPETEKHVGAEMTVGELCKAAITLSDNTAGNLLLESLGGP +EALTKWLRSIGDTSTRLDRIETALNEAKKDDPRDTTTPDAMLDTLGNLTIGSVLSEPSRT +QLIDWMVANTTGAARLRAGLPEEWKIGDKTGTGNNGSAADIAVLWPESGSPILVATYIAE +ATAPVSELNEVFAEVAKIAA--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RHB7_9BACT +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQGLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLPAFLRQMGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00061C387F +----NKKFLQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKIVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis acidicola TaxID=2596893 RepID=A0A5N0URZ0_9PSEU +-----QDFQQLEATFGARLGVYAVDTGTGRTV-TYRADERFPFASTYKALAAGAVLQREP +--LEELDRKITYGSGDLVNYSPVTEKHVADGMSLRDVMDAALRYSDNTAGNLLFAELGGP +AGFTAAMRALGDTTTQSDRRETELNEGTPGDLRDTSTPRALADDLRAFGVGNALPDNKKK +VLLDFMRANTTGGELIRAGVPQGWQVADKTGNASYATRNDIAVVWPPQGAPIVVAILSTK +PAKDAGYDNKLIAQAASTALGSf +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=G9Q733_9BACI +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B4LD20_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKGDLVEYSPVTERHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMEDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN +ILTEWMKGNATGDKLIRAGVPNGWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIEEAAKVVID-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0003A4AB70 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNG +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI001143864B +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKDDLVEYSPFTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPTRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. FMQ74 TaxID=1913579 RepID=UPI0009F2CB42 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTNAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus TaxID=1386 RepID=UPI0011449304 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus sp. Cedars TaxID=1980674 RepID=UPI0011653064 +------DFVQLESKFSARLGVYAIDTGTERIV-AYRPDERFAYASTFKALAAGAVLQQNS +--MDTLDKVITYTSKDLVTYSPITEKNVNTGMTLRELSEAAIRYSDNTAGNLLLKELGGP +DGFRTALKQAGDNVTNPERFETDLNEAIPGDNRDTSTPRALATTLQAYTVGDELPTDKRT +LLIDWLKGNTTGDKLIRMAVPEGWEVGDKTGAGGYGTRNDIAVIWPPNKEPIVIAILSSR +DTPDATYNDALIAQAAKVALD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI00111BF330 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2A7BHS8_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces iakyrus TaxID=68219 RepID=UPI00068B26E4 +----TARLRELEQEHTARLGVYARNMRTGRTV-TYRADERFPMASVFKTLAAAAVLRDLD +RDGEFLARRVHYTQEYVTKYSPVTEDHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP +TAITRFARSIGDRVTRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGSALERRDRA +RLTDWLLRNTTSLERFRKGLPADWLLADKTGGGRYGGNNDVGITWPPDGPPIVMSVLTTQ +PEEDAPADNPLVAGAAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000D73C620 +----NKKLVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKNDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 112mf TaxID=1761752 RepID=A0A1H4G6G2_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHADTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011452478 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKTLAAGVLLQQNS +--IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=5 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1D3PIK5_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. DSL-17 TaxID=2567941 RepID=A0A4S4BHX3_9BACI +--ATNHDFAKLEEKFDAKLGVFALDTGTNQTV-TYHPDERFAYVSTHKALAVGALLQQKS +--IEDLNQRITYTREDLVNYNPITEKYVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP +AGFKKALEEIGDNVTNPERFEPDLNEVNPGETHDTSTPRALATSLQAFTLGDTLPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DKKDADYNDELIAEATEEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF1BF18 +----NQSFAKLEKEYDAKLGIYALDTDTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=B5UTC4_BACCE +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=15 Tax=Bacillus TaxID=1386 RepID=A0A2B8W8Q1_BACCE +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFDC1F4 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELGDASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFMLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BFCD031 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDNRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SAFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus arenosus TaxID=1229153 RepID=A0A3D8PI95_9BACI +--SADNEFAKLEETFDARLGVYAIDTGSGQVI-SYQEDERFAYTSTFKALASGALLQKNE +--IEDLNKVITYTEDELITYSPVTEKHVDTGMTLREIIEAAVRYSDNTAGNLLLNELGGP +EGFEEALREIGDEVTEADRFEPTLNTAVPGDSQDTSTPKAVATSLKEFAVSDLLSEEKRA +IFNDWLSGNATGDKLIRAGVPDDWKVGDKSGAGGYGTRNDIAVIWPPDREPIVIAILSSR +DTEDATYDDALIAEAAKVVVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000A35B941 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN) TaxID=398527 RepID=B2TE74_PARPJ +--AIRRRLAEIEAASGGRLGVSIVDTMSGVHA-GLRTDERFPMCSTFKILVAGAVLARTD +RGEESLQRRVVFSLSDVVSNSPATSKHTRELMSVAELCKAAITLSDNTAANLLLSTFGGP +AGLTAFARSLGDRVTRLDRIEPALNEGTPGDLRDTTTPNAMLGNLRELLLGERLSSSSRA +QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPVLVTVYLTE +TDGDAARSNTAIADVGALVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000F095C3D +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bordetella genomosp. 9 TaxID=1416803 RepID=A0A1W6Z5S5_9BORD +----HAACARLERAHDRRLGLYAIDTGNGRTV-GYRAGERFAFCSTFKALLAGAILARLK +ADAGILDRRILYTRHDLVPYSPITEKHAGGSMTVADLCAAALQYSDNTAANLLLHAVGGP +AALTGYARALGNRSFRLDRYEPALNSAIPGDPRDTVTPADMAASLRSLAVGNALTAGGRE +RLPEWLLGNTTGANRIQAGAPAGWRVGDKTGTGDYGAANDIAIVWAPDRPPIVLAVYTAA +SATAAAADEPLIAAATQLAI--- +>[subseq from] UPI00143B069D UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00143B069D +---AVQRLSDLERTFDGRLGVFAFDMGSGASL-AWRSEERFPVCSTFKAFLAAAILHRST +SDAGLLDRVISYPLEELVFHSPVAQQHVHSGMSVRDMCAAAIQYSDNTAANLLMRILGGP +DAVTAFMRQTGDMGFRLDRWETDLNTAIPGDPRDTSTPVAMSRSLDRLLFGDVLSDTHRA +VLQDWLKGNTTGASRIRAGVPEGWMVGDKTGSGSYGTANAIGVLWPPGRKPVIVSIYTTQ +HYRGAVWRDDIVAQATRIIV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A443TGC9_BACMY +----NHSFVKLEKEYDAKLGIYALNTGTNQTV-TYRSDERFAYASIHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKAIATSLQDYALGDILSTEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Pseudomonas TaxID=2583993 RepID=UPI0013784745 +-eSLEQKLSALEKRANGRIGMALIESGSQRML-TYRGDERFAMASTFKALLAGAVLQKSV +GQPGLLSKRVTYDKASLVVYSPVTEQHLEEGMTVSELCKAAVEWSDNSAANLLLKELGGP +ASVTQLAMSLGDDKTRLDRWEPELNSAIPGDERDTSTPLSMARNLLKLTVADGLPKEQQQ +LLVSWLKDSKTGAQSIRAGVPGGWPVGDKTGAGEYGTTNDLAIIWPPTGQPLVLAIYFTQ +REQKAQARRDVLASVSKMVLAEf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDD5A1E +--DVDKQLGDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAILDSIGLLTLGNTLSETSRD +QLVNWLVGNTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAPAKDVEAVFAEVSRIVT--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8Z8T7_BACCE +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0002799638 +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRFSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium fabae TaxID=573179 RepID=UPI000F861254 +-dDIQRRLAALEKRTGGRLGVSVLDTQTSISF-NYRGSEAFPMCSTFKALAAGFVLARVD +KGEENLQRRVSYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAANLLLESFGGP +PVLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSILTEASCD +RLIAWLVASTTGKERLRAGLPQDWKIGDKTGTGPNGSLGNIAVIWPPDRGPIVAAVYIGE +ATVPVKELNPVFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces chryseus TaxID=68186 RepID=UPI00110FEE2D +-----RELKALERKFDARLGVYAVDTGTGREV-AYNDRERFAYASTFKALAAGAVLRTYT +--LSGMNQVVTYSEDDLIAHSPVTEKHVGTGMTLRELCDAAVRFSDNAAANLLLDALGGP +KGLDAHLARMGDDVIRMERREPELSRWAPGDTRDTSTPRAMAEDLRAFVLGDVLGKDERA +QLTTWLRTNTTGDETIRAGMPEGWVVGDKTGTGGYGARNDIAVVWPPGSAPIVVAIMSNR +DEEDAGHDNRLIAQAASVVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B4BA139 +----NDSFAKLEKEFDAKLGIYALDNDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=2 Tax=Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / BCRC 12538 / CBS 129.76 / JCM 10878 / NBRC 16125 / NRRL B-16091 / INA 9442) TaxID=644283 RepID=D9TA79_MICAI +------ELAALERRSGARIGVFALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFERALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD +LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR +DSRDAEPDDALVAQAARAAVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. NH11B TaxID=1866314 RepID=UPI0009214375 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVGTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009E25156 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRSNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus swezeyi TaxID=1925020 RepID=A0A5M8RG66_9BACI +--EVKHHFTKLEDQFDARLGVYALDTGTNQTV-TYRSDERFAFASTLKALAVGALLQQKS +--IKDLNQNITYTHDDLVSYSPITEKHADTGMTLKELSDAALRYSDNTAMNLILQQLDGP +KGLKKALRKIGDHVTNPTRFETELNDVQPGETRDTSTPRALAASLQAFTLGDALPIEKRE +LLIDWMKRNTTGDSLIRAGVPKGWEVADKTGAASYGTRNDIAIIFPPNRCPIVLAILSSR +DKKDAEYNDELIAEATKDVINAf +>[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI0011A4460A +-tEMKDDFAKLEEQFDAKLGIFALDTGTNQTV-AYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITENHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVMK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus niacini TaxID=86668 RepID=UPI00052FBCEB +--HIHREFGELESKFDARLGVYAIDTGTNQTV-SYRSHERFAYASTYKALAAGALLQQYS +--IDQLEELVTYNSEDIVSYSPVTELHVDTGMTLGEVIEAAVRYSDNTAGNLLLEKLGGP +EGFETALRQIGDKVTEADRYETDLNSAIPGDTRDTSTPKSLATSLKAFAVSDLLPTEKRK +ILTDWMRGNATGDALIRSGAPTGWEVADKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR +DTQNATYNNTLIAEAAKVALN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0009BCFA2F +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF5410A +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKAS +--IEDLDQIIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRTGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora carbonacea TaxID=47853 RepID=UPI0009F312ED +------ELVALERRFDARLGVYAVDTGTGRTL-AYRADERFAYASTIKALAAGALLARTS +--EAELDRVVRYDRADLVPHSPVTQRHVSDGMTLRAVADAAVRHSDNTAANLMFTELGGP +AGLGRALRGIGDTVTNPTRTETSLNEAAPGDVRDTSTPRALAGSLRAYALGDVLSPADRG +VLVDWLRRNTTGATLIRAGVPAGWQVGDKTGAGGYGTRNDIAVLWPPDGAPVVLAVLSRR +DAKDAQPDDALIAEAARVALD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FDA1_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRGLCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 196mf TaxID=1761754 RepID=A0A2V4X4A6_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000BF2E407 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Polaromonas sp. (strain JS666 / ATCC BAA-500) TaxID=296591 RepID=A0A1G9VW27_POLSJ +--SVTRRLVAIEKTSGGRLGVSMLDTGSGAKY-GYRAGERFPMCSTFKLLAAALVLHRVD +SGQEQLGRRIPIAAGDILPHSPTTQQHIGPQLPMAALCEASIIVSDNAAANLMLASFGGP +AGLTAYLRGLGDKMTRLDRTEPELNESAPGDVRDTTTPDAMLATVHKLTLGSALSDASRQ +LLVQWLQANTTGDRRLRALLPPGWRVGDKTGSGARGSTNDVGLIWPPGGAPLLVAAYLTG +TKQPAAQRDAALAQVGQLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BEE430C +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. RV43 TaxID=1661387 RepID=UPI00064C4197 +------ELAALERRSGARIGVYALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFARALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD +LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR +DSRDAEPDDALVAQAARAAVT-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-4489 TaxID=1609095 RepID=A0A0X3V2K1_9ACTN +--SLDSHLSDLEHRYGARLGVYARNVRTGQVI-AHRAQERFAMCSTFKAIAAAAVLRDQA +-HCAPMDKVIHYPPTDILPNSPRTEEHVDTGMAVRDLCGAAIQYSDNTAGNLLLRQIGGP +GGLTAFLRSIGDPVTRLDRWEPDLNTAIPGDLRDTTTPEAICRSYEQLTLGRALTAPDRE +RLVAWLKGNTTSDERFRAGLPHTWTVADKTGTGSYASANDIGVAWTTRHTPIVLAVLSTK +PTKDAPVDNALVADAARVIAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. C11 TaxID=1178594 RepID=UPI00140BD4E3 +--HIHREFAELESKFDARLGVYAIDTGTNRTV-SYRPHDRFAYASTYKALAAGALLQHYS +--IDQLDELVTYNSEDIVSYSPVTQLHVDTGMTLREVIEAAVRYSDNTAGNLLLEKLGGP +EGFETALRQIGDNVTQVDRYEPDLNSALPGDTRDTSTPKSLATSLKAYAVSDLLSIEKRK +ILTDWMRGNTTGDALIRAGAPTGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR +DTQNATYDNTLIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora carbonacea TaxID=47853 RepID=A0A1C4VS08_9ACTN +------ELVALERRFDARLGVYAVDTGTGRTL-AYRADERFAYASTIKALAAGALLARTS +--EAELDRVVRYDRADLVPHSPVTQRHVSDGMTLRAVADAAVRHSDNTAANLMFTELGGP +AGLGRALRGIGDTVTNPTRTETSLNEAAPGDVRDTSTPRALAGSLRAYALGDVLSPADRG +VLVDWLRRNTTGATLIRAGVPAGWQVGDKTGAGGYGTRNDIAVLWPPDGAPVVLAVLSRR +DAKDAQPDDALIAEAARVALD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8V0_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLRGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0013D7D356 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFKKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNG +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKI5_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRRLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSEAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAER-------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000E2E7889 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF616A1 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILIEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000BA9E42D +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNEWFAYASTYKVLAAAAVLKTSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLHQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALANDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-34 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1C8FRX1_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF5A2F9 +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKTLATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase CRH-3 n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A2R2V0K8_9NEIS +----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPLCSSFKGFLAAGVLAQSQ +DKPGLLDKRIRYSKTALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLKEINGP +AALTAFMRSIGDARFRLDRLEPELNSAIPGDPRDTSTPKAVAESAQKLALGKALPEPQRQ +RLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH +AKKEAKHSDEVIAAAARAALEAf +>[subseq from] class A beta-lactamase n=1 Tax=Pectobacterium carotovorum TaxID=554 RepID=UPI000B96F99A +-pDTLDTVKDAENKLKARVGYTELDLTNGMILeGYRPEERFPMMSTFKVLLCSAVLSRVD +SGKEQLDRRIHFDQSDLVTYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLSTIGGP +QELTIFLRKTGDHVTRLDRWETALNEALPGDERDTTTPKAMAETLHKLLTGKILTVASQQ +QLMDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYLTG +GQATIEERNKQIAEIGTSLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas floridensis TaxID=1843580 RepID=A0A1A9M5L7_9XANT +--MLRAQWAEIERGTGGRLGISLLDSATGWRL-GQRQNERFPMCSTFKFVLAAAVLQRVD +ESRLTLAQPVKIRASDMLEHAPVTKRHVGSALSVGELCQATMIYSDNPAANLLFPLVGGP +PGVTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG +AKVDDAARDAALKAVAAAVRD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000DC1EE66 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEELNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKIVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium americanum TaxID=194963 RepID=A0A4R2BXJ4_9RHIZ +--DVTKLLAELEKRTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACVLARFD +RGEEKLDRRITFGKDVLLPHSPVAEKHVGGDMTVAELCDAAVTISDNAAANLLLESFGGP +AGLTSWLRSIGDRTTRLDRTEPDLNEAKFGDPRDTTTPVAMLETIGKLAFGSVLAESSRR +QLVEWMVANTTGDARLRAGLPKDWQIGDKTGTSSTGAVSDIGFAVPKGRGPILITVYTGE +AKVEPAELNPVFAEVGKIVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0G3FB19_ECOLX +-----VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATRDER--------------- +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. FT68W TaxID=2654255 RepID=UPI0012655229 +--AAQAQLAALEHAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLDQHLRYEKKELVTYSPITEKHLADGMNVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAYARSIGNTVFQLERWETELNSAIPGDVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis HD-771 TaxID=1218175 RepID=J3ZWJ7_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Roseovarius tolerans TaxID=74031 RepID=A0A0L6CX15_9RHOB +-dALRQTVQDVEARIGGRIGYAVTDLNSGQEW-GSRPDERFPMSSTFKALLCGVILARVD +AGAEALDRRITFGRDDLVTYSPVTDRHLGTGMTVGELCRAAITMSDNTAGNLLLATIGGP +EGFTETLRDMGDATTRLDRWETALNEGAPGDERDTTTPRAALSTLQALLFGDMLTAASRQ +QLSDWMIADAVADDLLRASLPEGWIIGDKSGAGGHGSRSIIAVVWPTPNHPALVTIFMTG +ADADMTDRNAAIAEIGAAIFA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA2-9 TaxID=1053204 RepID=R8DAZ4_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIMLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000CF3B19E +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPFMSTGKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLTTTIGGP +KELTAFMHNMGDHVTRFDRYYGELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia amamiensis TaxID=404578 RepID=UPI00083021A3 +-----ASFLEMETNHAARLGVYAIDTASGHTV-AYRDGERFPMASTFKGLACGALLRDHP +LSTGYFDQVIHYPRTDLVEYSPVTEKHVDTGMTVAELCDAAITVSDNTAGNQLLKLLGGP +AGFTAFLRSIGDNISRLDRWETELNTAIPGDERDTTTPAALAADYRALVLGDVLGEPERE +RLKSWLIANTTGGKRIRAGLPAGWTVGDKTGSPAYGSALDVAIAWPPGRGPLVIAVLSTK +FEQNAQADNPLVADAARAAVE-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000CF4EC26 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPFMSTGKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLTTTIGGP +KELTAFMHNIGDHVTRFDRYYGELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZHY3_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWRKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDG------------------ +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillus sp. FSL R5-808 TaxID=1227076 RepID=W4B529_9BACL +------DFVQLESKFSARLGVYAIDTGTERIV-AYRPDERFAYASTFKALAAGAVLQQNS +--MDTLDKVITYTSKDLVTYSPITEKNVNTGMTLRELSEAAIRYSDNTAGNLLLKELGGP +DGFRTALKQAGDNVTNPERFETDLNEAIPGDNRDTSTPRALATTLQAYTVGDELPTDKRT +LLIDWLKGNTTGDKLIRMAVPEGWEVGDKTGAGGYGTRNDIAVIWPPNKEPIVIAILSSR +DTPDATYDDALIAQAAKVALD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar guiyangiensis TaxID=180871 RepID=A0A242XKJ5_BACTU +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFTFASTSKSLAVGALLHKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A1N7EDQ1_9BACI +----NHAFAKLEEKFDAKLGVFALDTGTNQTV-AYHPDERFAYASTHKALAVGALLQQKS +--IEDLNQRITYTPEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP +TGFKKALEEIGDNVTNPERFEPDLNEVNPGETHDTSTPRALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDISIIWPSKGDPIVLAVLSSR +DKKDADYNDDLIAETTKEVIK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. H-KF8 TaxID=1727216 RepID=A0A1A5P2G9_9ACTN +---ATGDFEELERTYGARLGVYAVDTGSGREV-AHNDDERFAYASTFKAFAAAAVLREHS +--PSGMDEVITYSGDDLVAHSPVTEKHVGTGMTLRELCDAAVRHSDNTAANLLFDALGGP +KGLASALEEVGDTVTRVERREPELNQWAPGSTRDTTTPRAWAGDLRAFVLGDALDGKERA +QLTKWLRTNTTGDELIRAGVPEGWVVGDKTGGGGYGVRNDIAVVWPPDAAPLVMAIMSNR +RTADAGHDDELIAEAASVVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI00042F1B34 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNEWFAYASTYKVLAAAAVLKTSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLHQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALANDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5YM21_9BACT +--DFANRILPIEERAGARIGVAALDTGTGKRL-DYRSEERFPMCSTFKFLAAAAVLKRVD +EGKENLERFIRYSSQDLLEYAPVTKAHLKDGMTLAALCAAAIEQSDNTAGNLLLDVIGGP +SGLTNFARSIGDQITGLDRKEPELNSAIPGDERDTTTPAAMCADLQRLLLADVLFESSRQ +EFEDWLRHNETGALMIRAGVPQTWSVGDKTGRCANGATNDIAILRPAGRAPILIAIYCIG +STAPADDRAAAIAETARAVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora chalcea TaxID=1874 RepID=A0A365V128_MICCH +------ELAALERRSGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVVRYRRADLVAHSPVAERHVETGMTLRDAAEAAVQYSDNTAGNLLFDALGGP +AGFARALREVGDQVTRPVRTEPELNAATPGDERDTSTPRALAGSLRAYALGETLRPADRD +LLLGWMRASTTGSGLVRAGVPAGWPVADKSGTGGYGTRNDIAVVWPPDGAPIVLAVMTSR +DSRDAKPDDALVAQAARATVTAf +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001145488F +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2B6MYI9_9BACI +----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDFVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIENRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00123778E7 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNEWFAYASTYKVLAAAAVLKTSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLHQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALANDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000F02F8E6 +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNEWFAYASTYKVLAAAAVLKTSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLHQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALANDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. ABP14 TaxID=1892404 RepID=UPI0011A666E7 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=B8ZHX8_KLEOX +--AIQQKLTNLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SHPDVLNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAK----------------- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI001145393B +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVNYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus anthracis TaxID=1392 RepID=A0A2A7DBQ6_BACAN +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDFC433 +--EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD +KGEENLERRVVYEKEQLIAYSPETEKHVGGEMSVGDLCKAAITLSDNTAANLILESLGGP +KELTNWLRTLGDGSTRLDRIEPDLNDIAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK +TLIEWMVANTTGNERLRTGLPETWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTN +ATVATAEINPVFAEVGRIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora sp. 7K502 TaxID=2530387 RepID=A0A4R4Z662_9PSEU +-----DRLVELERKFDARLGLYALDTGTGATI-AHRADERFAFCSTFKALAAAAVLHRNP +--LPHLDEVITYTESDLMKSAVITGQHVDTGMTIRELCEAAVRYSDGTAGNLLLRDLGGP +AELTAYARSLGDAVTRMDRFEPDIVEATPGDPRDTTSPRAFGATFQKIVLGDALPAEKRA +FLRGLLERNTTGAQRIRAGVPQGWTVADKTGTGDYGTLNDIAVVWPPNAPPLVLAIMSSK +ATKDAEYDQALIAEAAAHVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BED89C9 +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPSNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 01416 TaxID=2203196 RepID=A0A429DAP0_9PSEU +--QFHDRLMELEKKFDARLGVYALDTEGGSTV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVRYSREDLMKHAPVTGQHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +AALTAFTRSLGDTVTRMDRVEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTADKRD +FLRDLLQRNATGAERIRAGLPPGWTVADKTGTGDYGTLNDIAVLWPPAKAPIVLAIMSSK +AAKDAPYDQALLAEAAKYVAETf +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00114522CB +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. BRIP62415 TaxID=2182390 RepID=UPI000F8E202A +--ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD +KGELTLGKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWNIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG +ATVDAAARDAALKAVAAAVA--- +>[subseq from] Beta-lactamase n=6 Tax=Bacillus TaxID=1386 RepID=C3DK16_BACTS +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. BRIP62409 TaxID=2182388 RepID=UPI000F8D2887 +--ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD +KGELTLGKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWNIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG +ATVDAAARDAALKAVAAAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Hydrogenovibrio marinus TaxID=28885 RepID=A0A066ZN74_HYDMR +--NFKQQISELESTFGGRLGVAVWDASSGFQL-QYRGNERFAMCSTFKFLLAASVLAKVD +AKEESLNRVVTYSTSDLLDYAPITRKNLRNGMTISQLLAAALQYSDNTAANLLFEPVRGP +QGLTTFMRSFGDKETRVDRIEPHLNTNIPGDERDTTTPNAMLKSMKKILLGHVLSEASKN +QLTQWMLNNTTGANKLRAGIPTYWPVGDKTGSGNNGAMNDIAIMWPDADDPILVAVYYTG +SKEPFETKNHVLEQVGRIISQQf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-37 TaxID=1463903 RepID=UPI0004CC37E7 +------SLTDLEREYGARLGVYALATGTGATV-VHRADERFALCSTFKTLAAAAVLDRHP +--VPRLDRRVTYTRADLITYSPVTEKHVDTGMSLRDLCDAAVRYSDNTAANLLLREIGGP +RALTAHLRGLGDRVSRLDHTEPGLNGNPPGDPRDTTSPRAVAADYRALVLGDALPAAKRE +LLADWLVRNTTGDLRVRAGVPRDWKAGDKTGTGEWGRANDVAVLWPPHGAPLVIAVLTER +PDREAAASDALVAEATRRVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus albus TaxID=2026189 RepID=A0A4Q0X7G8_9BACI +-qATHKEFSQLEKKYDARLGVYAFDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALIQMSDRVTMSDRFETELNEAMPGDNRDTSTAKAIATNLKAFTVGNALPNHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium sp. CCBAU 05631 TaxID=794846 RepID=A0A249NQD7_9RHIZ +--DVTKLLAELEKRTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACVLARVD +RGEEKLDRRITFGKDVLLPHSPVAEKHVGGNMTVAELCDAAVTISDNAAANLMLESFGGP +AGLTSWLRSIGDGTTRLDRTEPDLNEAKFGDPRDTTTPVAMLETIGKLAFGSVLAESSRR +QLVEWMVANTTGDARLRAGLPKDWQIGDKTGTSSTGAVSDIGFAVPKGRGPILITVYTGE +AKVEPAELNPLFAEVGKIVA--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF1E021 +--AMYKDFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Sinorhizobium TaxID=28105 RepID=A0A2S3YHF7_9RHIZ +--DVTKLLAELEKRTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACVLARVD +RGEEKLDRRITFGKDVLLPHSPVAEKHVGGNMTVAELCDAAVTISDNAAANLMLESFGGP +AGLTSWLRSIGDGTTRLDRTEPDLNEAKFGDPRDTTTPVAMLETIGKLAFGSVLAESSRR +QLVEWMVANTTGDARLRAGLPKDWQIGDKTGTSSTGAVSDIGFAVPKGRGPILITVYTGE +AKVEPAELNPLFAEVGKIVA--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF1FBC7 +--AMYKDFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2C4FPZ3_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDNRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SAFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2C4Q8T3_9BACI +----RHSFVKLEKEYDAKLGIYALDTDTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPKRFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPTEKRN +FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGAYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=Q737V7_BACC1 +-qATHKEFSQLEKKFDAQLGVYAIDTGTNETI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPITEKHIDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPDDKRK +VLTDWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAIYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8MUT7_9BACI +--AMYKDFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A3D9VBM3_BACMY +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRARVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIMLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. LMG 8989 TaxID=1591156 RepID=UPI00136D4DA1 +-qTLQQRLAEIERRSGGRLGVSLLD-GSGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD +RGELALERRLPVRKADLLAYAPVSERHVGGALSVAELCQAAMIYSDNTAANLLLPLVGDP +PGVTRFLRALGDAQTRLDRNEPSMNDVVAGDLRDTTTPAAMAATMRTLLLGEALQPASRQ +RLIAWMRDNRTGNDCLRAGLPAAWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG +ATVDSAARDAALKAVAQAVVA-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A4V2VJD4_9BACI +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDASTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Marinactinospora thermotolerans DSM 45154 TaxID=1122192 RepID=A0A1T4SZX3_9ACTN +----AGDFERLEGEFDARLGVYAIDTGSGETV-THRADERFAYASTIKALQVGAVLQQNT +--LEEMEEVVTYDEEDLVTYSPITEQHVDTGMTLREVSDAAVRYSDNTAANLLFEELGGP +AALDAALEGIGDDVAEVVRIEPELNATAPGDTRDTSTPRAMADSLRAYALGDVLPADERA +VLTDMLKGNTTGDALIRAGVPDDWEVGDKTGAADYGTRNDIAILWPPDEDPIVVAVMSDK +DTPDAEYDDALIAEAAQVVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A3A2YK26_BACCE +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRKMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGNKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH +DKEDAEYDDTLIADATKIVLE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus paramycoides TaxID=2026194 RepID=A0A1J9UNB7_9BACI +-------FVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLEQRIKYTSKDLVNYNPITEKYIDTGMTLKELVDASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAEYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A679GZC0_9BACI +----DDSFAKLEKEYDAKLGIYALDTGTNQTV-SYRSDDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKTIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH +DKKDAEYDDKLIADATKTVLN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1B2VWE5_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERN-------------- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A150EQV6_BACCE +-qATHKEFSQLEKKFDAQLGVYAIDTGTNETI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPITEKHIDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPDDKRK +VLTDWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAIYDNQLIKEAAEVVID-- +>[subseq from] Carbepenem-hydrolyzing beta-lactamase KPC n=1 Tax=Duganella phyllosphaerae TaxID=762836 RepID=A0A1E7WVQ3_9BURK +----AAQLARLESEAKGRLGVAAINTADGRIL-SHRGDERFPLCSSFKAMLAAAILQHEP +---SLLDRRIRYTAADLVSHSPVTQQNLADGMTVAELCAATIQTSDNAAANLLMKQIRGP +AGVTAYARSIGDKVFRLDRWETELNSAIPGDPRDTTTPLAMMKSLQSVTLGPALTVDKRK +LMTQWLVGTTTGDTRIRAGVPYDWQVGDKTGTGAYGTTIDIGVVWPTGKAPVVMALYFTQ +PGQGDKANSEILAAAARVVVEAf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar pingluonsis TaxID=180881 RepID=A0A243BB67_BACTU +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLIEIGDTVTNPERFEPELNEVHPGETHDTSTSKALATSLQAFALGDVLSTEKRN +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia shimofusensis TaxID=228596 RepID=UPI000A00AB84 +------RFADLESTSGARLGVFAVDTGTGRVV-THREHERFPMASTFKALACGALLRDHP +LSSGYFDQVIHYAAGELVEYSPVTERHVESGMTVAQLCDAAITVSDNTAGNQLLKLLGGP +AGFTAFLRSLGDDTSRLDRWETELNSAIPGDERDSTTPAALAADYRALVVGDTLAEPERA +RLTSWLVANTTGDARIRAGLPADWTVGDKTGSPAYGSALDVAVAWPQGRAPIVIAVLSTK +SEPDAEADNALVAAAARAAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces chryseus TaxID=68186 RepID=UPI00110FF26C +-----RELKALERKFDARLGVYAVDTGTGREV-AYNDGERFAYASTFKALAAGAVLRTYT +--LSGMNQVVTYSEDDLIAHSPVTEKHVGTGMTLRELCDAAVRFSDNAAANLLLDALGGP +KGLDAHLARMGDDVIRMERREPELSRWAPGDTRDTSTPRAMAEDLRAFVLGDVLGKDERA +QLTTWLRTNTTGDETIRAGMPEGWVVGDKTGTGGYGARNDIGVVWPPGSAPIVVAIMSNR +DEEDAGHDNRLIAQAASVVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. YR295 TaxID=1500257 RepID=UPI00055C64E8 +-nDIEKQLAALEKRTGGRLGVFVLDTSTNVSF-GRRQDERFAMCSTFKALAAAFALARAD +KGEEKLDRRIPVLKKDLLSYSPVVEKHVGGGMTVRELCDAAVTYSDNAAANLLLASFGGP +KGLTTWLRSIGDETTRLDRTEPELNEAKIGDPRDTTTPMAMTETLGRLLLQDVLSPSSRD +QFTAWLVANATGDRRLRAGLPQDWMIGEKTGTSGRGEAGDIGFMRPRDGHTILASVYIAE +GKKPTKELEPVFADVGKLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus halodenitrificans TaxID=1482 RepID=UPI00045D1844 +----NEKFAEIEKEYNARLGVYAIDTGTNQRV-QYNSDDRFAYASTFKVLASAILLKQNS +--IEDLERVVTFSKDDLVTYSPVTEKHVDTGMTLGEISEAAIRYSDNTAANLLLEELEGP +EQFKQALRDLGDDVTQPERFETELNDFAPGKKRDTSTPKAMANTLKKVALDDFLPDDKRE +LLHNWMKGNATGDKLIRAGAPAEWVVGDKSGAGSYGTRNDIAIVWPPDREPIVIAVMSRH +EEEDAEYDDALIAKAAEIALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0002E9CB85 +---ITKKFVQLEQKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKVLAAAAVLKKNP +--IEKLNEMIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFENSLKQIGDQVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTADKRT +ILTDWMRENATGDELIRAGTPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR +FTKDANYDNALIAEAAKVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillaceae bacterium GAS479 TaxID=1882832 RepID=UPI000B82E9B7 +--AFRRSFVQLEEKYGARLGVYAIETGTGRSI-AHRPDERFAYASTYKALAAGFVLKHST +--ANELERVITYSKDDLVSYSPVTELHVNTGMTLKQLCEAAVRYSDNTAGNLLFKQLGGP +KGYEVALREIGDVVTQVDRLEPELNEAVPDDTRDTSTPRALATILSNFTVGDVLADDKRS +ILMDWMSGNATGDELIRAGVSEDWKVADKSGAGSYGTRNDIAVVWPPSGAPVVIVIMSSR +DEQNADYDNALIAEAAKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDE0645 +--DVDKQLGDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD +QGAEKLDRRVTYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAILDSIGLLTLGNTLSETSRD +QLVNWLVGNTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAPAKDVEAVFAEVSRIVT--- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A5S4JEZ3_STRGR +-----AAFRKLEREFGARLGVYAVDTGTGREV-THNDRERFAYNSTFKALQAGVVLSTYS +--LEGMDERVAYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +AGLDAALEKLGDDVTRMDREEPELSRWTPGEERDTSTPRALAGDLRSLVLGDALPAPERK +QLTAWLRTNTTGDAVIRAGVPDNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +STKDAEPADELIAEAASAVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD94499 +--DVDKQLGDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD +QGAEKLDRRVTYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAILDSIGLLTLGNTLSETSRD +QLVNWLVGNTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAPAKDVEAVFAEVSRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCCA22 +--DVDKQLGDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD +QGAEKLDRRVTYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAILDSIGLLTLGNTLSETSRD +QLVNWLVGNTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAPAKDVEAVFAEVSRIVT--- +>[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. W64 TaxID=1735583 RepID=UPI0007B25FAE +-----DTVGQLEDEVGGRIGVVLRHTGSDWAV-EHRADERFPMASTFKALLCGAVLSRVD +RGEESLGDLVTYKATELVSYSPVTENHVASGMSVGQLCEATVTMSDNSAANLLLKRVDGP +EGLTRFLRGLGDRVTRLDRNEPAMNEARRGDPRDTTSPSAVLKTLDRLLFEDVLLPSSRA +QLQQWMVDDKVADELIRKHLPKGWRIADKSGAGHNGSRGIIGVIWPETGKPYLAAAYMTG +SDASFKQRNAVIAEIGKAMIE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Nocardia mangyaensis TaxID=2213200 RepID=A0A1J0W304_9NOCA +-----PSFADLESEYGVRLGLSVVDTGTNTAV-DHRADERFPIASMFKGIACGALLQAHP +LDTGYFDKVIHYTADDLVEYSPETEQHVETGMTVAELCHAAITVSDNTAGNLLLRELGGP +EGFTAFVRTLGDTVTRLDRWETELNTAIPGDERDTTTAAAIAADYRALVLGTALPAPERA +QLADWLRANTTGGERIQAGVPADWTVGDKTGTPAYGTALDVAIAWPPGREPIVLAVLSTK +SERDTDPSNESIAEATRLAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2B6D9F5_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=7 Tax=Bacillus TaxID=1386 RepID=A0A2B9EAU7_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPVIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia steynii TaxID=1245441 RepID=A0A4R0XEZ0_9BURK +--ALEKQLAQIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD +QGKDQLERKIVYSKDVVVANSPVSGPRAGSDMTVAELCEAAITRSDNTAANLLLDSIGGP +AALTAFARGIGDRITRLDRNEPTLNEALEADPHDTTTPAALLADMRALLLGEHLSTASRE +QLTAWLAANKTGDTRLRAGLPKAWRIGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG +ATATSTQRDAAIAQVGALVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0002799AE4 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella TaxID=570 RepID=A0ESF8_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQQFAR--------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides (strain KBAB4) TaxID=315730 RepID=A9VH74_BACMK +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8ECC7_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQAI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LETLDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A243E9D3_BACTU +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A5P9Y4L0_BACCE +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPEDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKRA---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000EA0284F +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPEDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKRA---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2V2H5P5_BACTU +----DNSFAKLEKEYDAKLGIYALDTGTNQTV-SYQSDDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKTPIVLAILSNH +DKEDAKYDDKLIADATKTVLN-- +>[subseq from] Beta-lactamase class A n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A1H4ZHI0_9ACTN +--DAHAALRRLERANRARVGAYAHNTVTGATV-AYRADTRVPLCSVFKTLAVGAVLRDLD +HHGETLARRVHYTDADLVANSPVTGKHLATGMTIAELCAAALQRSDNTAANLLLRALGGP +TAVTAFARSLGDRTTRLDRWEPDLNSAEPWRTTDTTTPAAIARTYTRLLLGDALTPADRA +RLTAWMKANETNTDRFRAALPRDWTLADKTGTGSYGTGNDVGVAWTPDGTPIVLAVLTGK +AQQAATPDDPLVADVTRVLAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. KC606 TaxID=2530379 RepID=A0A4R4TZF8_9ACTN +-----PDFTALERRFDATLGVYAADTGTGRTL-AHRADERFAYASTFKALAAGALLDVTS +--DAELDRVVRYGREDLVTYSPITEKHVGAGMTLRAIADAAVRYSDNTAANLILAELDGP +DGFERKLREIGDTVTDPARIETTLNEAAPGDVRDTSTPRAMATSLRAYALGDALSGADRA +ILVGWLRRNTTGAKMIRAGVPADWQVGDKTGSGGYGTRNDIAVLWPPQGAPIVLAVMSRR +DTKDAAYDDALIAEAAKLVV--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000FD6DA17 +-qATHKEFSQLEKKFNARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPVIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2B5T8K8_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRHIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0014312B47 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTNKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0011558F52 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPAEKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPVIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. COPE52 TaxID=2233998 RepID=A0A345XHN8_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEEHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVLVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI001155F3FE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEEHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVLVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobacter sp. Root1221 TaxID=1736433 RepID=UPI0009E76DB6 +------EWARLETSVGGRLGVAVLDTATGHCS-GHRVDERFPMCSTFKWLAAAVVLQRVD +AGVERLDRALPVAAHDIIDHSPVTVTRVGGTITLGELCEATITVSDNAAANLILAACGDP +AAVTAYARSVGDTVTRLDRNEPSLNEARPGDPRDTTTPAAMAATLNKVVLGDALTRASRE +RLAGWMRGTKTSGDRLRVHLPAGWRLGDKTGSGANGTTNDVGVVWVPGRAPVVVAMYLTE +AGASPAARNAVIAEAGRVVWT-- +>[subseq from] Beta-lactamase n=1 Tax=Roseomonas rosea TaxID=198092 RepID=A0A1M6JZ34_9PROT +---LPEAFRRIEAARGGRLGVAVLDAGSGRGA-GYRAAERFPLGSTFKLLVAAAVLARAD +AGRESMERRIRFTREDLVTYSPVTQRAVGGEMTLAALCEATMVTSDNTAGNLLLRVVGGP +EGLTAWLRGLGDGVTRLDRWETALNEARPGDERDTTSPAAMLASLRAVTVGNALSEAARA +QLIGWLRGNRTGDARLRARLPAGWQAGEKTGTSAHGTSNDVGLLWPPGDAPVLVAAYLTE +GAADGAVRDAALAEVGAAVAAAw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A4U3A2T3_BACMY +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITGKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIMLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFC43F1 +--ATYKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNMLFHKIGGP +KGYEKALRKNGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNGLPDHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sediminicola TaxID=946078 RepID=A0A1A9BA46_9ACTN +----DRAFRHLEETFDARLGVYAIDTGTGATV-GYRADERFAYASTFKALAAAEVLDETT +--DAELDRVVRYSADDLVTYSPITEKHVADGMTLRALADAAVRYSDNTAGNLLLRRLGGP +QRFEKELRGVGDKVTAPARYETALNEALPGDRRDTSTARALAQDLRAYAVGDSLDPADRD +ILNGWLRGNTTGGELIRAGVPDGWVVGDKTGSGGYGTRNDIAVVWPPDRAPIVLAVLSSR +DQKDADYDNALIARAAEVAI--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Hyphomicrobium TaxID=2619925 RepID=UPI0012DD3875 +-----NAFAGLEKQYGGRLGVAVVDTGSGERM-AYRADERFPMCSTFKLLIVGAVLHNVD +KGSERLDRWIPFQASDLLDYAPVTKTAVGNGMTMSDLCAAAIEYGDNTAANLILKAVGGP +DGATRYVRSLGDEVTRIDRFEPDANTCIPGDPRDTTTPAAMLADLKALVLGDALSANART +QLLGWLNGCKTAARRIPADLPAGWISGDKTGSGANGTANDVAIIQRPNKKPLLVAAYSTG +VAAKPADRDPMLADVGRIVARHf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A090ZAE1_BACMY +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIATTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC 01529 TaxID=2203205 RepID=A0A3Q8V861_9ACTN +--DARRRLRELEKGYPGRIGLHALNTGTGATL-GYRADERFAIASTFKVLAAAAILRRAR +EEPGLLDVLVRYGRDDLVTYSPRCEMHLPTGMTVRELCDATVTYSDNAAGNLLLRRLGGP +SGITEFARSLGDSRTRLDRWETDLNTNIPGDPRDTTTPAAMTANLRKLVLGDALAAPDRD +QLVRWLVENTTGDARIRAGLPEGWRVGDKTGSPAYGGVNDVAVAWPPGGAPLVISVYTTR +LDPDTPGEDRIAADMTRIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Erwinia amylovora TaxID=552 RepID=Q8GEF8_ERWAM +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGX +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTXMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVXYPTG +SQATMDERNRQIAEIGA------ +>[subseq from] Beta-lactamase n=1 Tax=Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161) TaxID=240015 RepID=C1F6V5_ACIC5 +--AFEDALAHLERSSGGRLGVALWQPATSLRA-GHRLHQRFPMCSTFKVMLVAAVLHRAD +QADGHLDRRLHYTQAQVLSWAPVTSKHVATGLTVRELCAAAITLSDNTAANLLLASLGGP +AAVTAYARTLGDTRTRLDRTEPTLNSAIPGDPRDTTTPSAMAHNLDRLLLGNALSPASRR +QLTAWMLDCQTGLHQLRAGLPAACKVADKTGNGSHGTSNDIAVLWPPHGAPVIITAYLTQ +STLTYSEQNAVLARVGRAA---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000CB18BD7 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=J8Z0E1_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8ZW82_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLHKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0007FB598F +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAAGALLRKNS +--LEALDQRIKYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. 123MFChir2 TaxID=1169144 RepID=UPI0012DCC85D +--TTMEKFEQLEKEYDARLGVFALDTGTKQTV-TYHPDERFAYASTHKALAVGALLQQKA +--IEDLDQRITYTREDLVNYSPITEKHVDTGMTLKELCDASLRYSDNTAGNLILKQLGGP +TGFKKELEEIRDNITNPERFEPYLNEVNPGETHDTSTPRALATSLQAFTLKDTLSTEKRE +LLIDWMKRNTTGGALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAILSSR +DKKDADYNDKLIAEATAEVIK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B4UAM0_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE09955 +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEYFPLCSTYKALAVGFVLARVD +QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDIETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAAAKDVEAVFAEVSKIIVD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. AcE210 TaxID=2292703 RepID=A0A371XSB6_9ACTN +---ARRRLRALEAGYPGRIGVHALHTGTGAVL-AYRAQERFAIASTFKVLAASAILHRAR +EEPGLLDVLIRYGRDDLVAASPRTELHLETGMTVRELCDAAITYSDNTAANLLMRRIGGP +AGVTAFARSLGDSVTRLDRWETDLNTNLPGDRRDTTTPAAMTEDLRALVLGDALHPLDRG +QLTRWLVENTTGDKRIRAGLPPGWRVGDKTGSPAYGGVNDVAVAWPPGGAPLVVSVYTTR +LDPDTPGEDRIAADITRVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1N6VBJ2_BACCE +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-SYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +STFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSKKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Gallaecimonas pentaromativorans TaxID=584787 RepID=UPI00067EDE25 +--DFSRTISDIESQYGGRLGVAAFDSRDGRQL-GYREHDTFAMCSTFKALLAAAVLKKAE +QGQLSLDTELSYGKGDLLDYAPVTAAHVDEGMTVSALADAAITLSDNTAANLLLAKIGGP +AGLTAYIRSLGDNLTRLDRTEPSLNTNLPGDPRDSTTPTAMVALWQKLLLGKALAPASRQ +QLLAWLKATQTGMAKIRAGLPGGWQAGDKTGSCENGGSNDVAIVWPSGQPPYLLAVYYSD +GLGGSAQKNAAIAAVSQAVAEQf +>[subseq from] Beta-lactamase n=2 Tax=Bacillaceae TaxID=186817 RepID=A0A2B6LWT0_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A2B5PXK7_BACMY +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=J9ASZ6_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BEBC295 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1C4AWZ8_BACMY +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BFBFDBD +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000A27C5F7 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI0011A1BBB5 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Wb2n-11 TaxID=1030533 RepID=UPI000AE222E2 +---FTRDFKELERKFDARLGVYAVDTGTGREM-AYNDGERFAYASTFKALAAGAVLRKYS +--LSGLDRVITYSRDDLAAHSPVTGKHVGTGMTLRALCDAAVRFSDNTAANLLLDQLGGP +HGLDAVLEEIGDDVTRMERREPELNQWAPGATRDTSTPRALADDLRAFVLGDVLGKGERA +QLTKWLRTNTTGSELIRAGVPGGWVVGDKTGAGGYGTRNDIAVVWPPDTAPIVVAIMSNR +GEEDADYDNELIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEB7E4C +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus proteolyticus TaxID=2026192 RepID=UPI0008FE7A78 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0007AB89AD +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BECC089 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=9 Tax=Bacillus TaxID=1386 RepID=A0A150BZR0_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0004DD410E +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0010C3201F +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SRB_8 TaxID=1969377 RepID=A0A328L755_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKHLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BDRD-ST196 TaxID=526976 RepID=C2SG64_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=K0FPJ7_BACTU +----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLEQRIKYTSKDLVNYNPITEKYIDTGMTLKELMDASIRYSDNTAQNLILTQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIENRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=A0A377QE36_9BURK +--TAQTQLAALEQAAGGRLGVAAWRQGSELRI-AYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMNVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ +QLDTWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. BJB426 TaxID=2048010 RepID=A0A2G3LBB9_9BURK +--AAQTQLAALEQAAGGRLGVAAWRQGSELRL-AYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMNVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPASQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGIAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000D52C6AB +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALSNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWQPDRAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEC2B4E +--ATYQEFFQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNATGDKLIRAGVPNDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Saccharothrix sp. ALI-22-I TaxID=1933778 RepID=A0A1V2QTN0_9PSEU +----SSDFSGLEAEFDARLGVYALDTGSGRAI-EHRADERFAFCSTFKALASAALLRRTE +--PADLDRRVTYTSADLVPNSPISGQHVAEGMTLRELMDAAIRYSDNTAANLIFNELGGP +AGFEEDLRGIGDQTTESDRIEPGLSEAVPGDTRDTTTPRAFAANLRTYVLGDVLPSDDRT +LLTEWLRNNMTGNETIRAGVPAGWVVGDKTGSGDYGTRNDIAVVWPPDGAPIVLAVMSDR +DEKEATRDNRLIARAAQTAV--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AD0117 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITFTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus panacihumi TaxID=497735 RepID=A0A3M8C5E5_9BACL +--DADQQLGQLEKEYDARLGIYAIDTETGRTV-SYRPDERFAYTSTFKPLAAGALLLKKP +--LDGLDKVITYKKEDLVTYSPVTEKHVEKGMTLREISDAAIRYSDNTAGNLLLKELGGP +AGLETVLQEVGDHITKPERYETDLNEAVPGDIRDTSTPKALATTLKAFTVDGVLPAEKQD +VLIDWLKRNTTGDELIRAAVPEGWTVGDKTGAGSYGTRNDIAVIWPPNQAPIVMAVLSSR +TEQDATYDNALIAKAAKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0008819B32 +----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLEQRIKYTSKDLVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SGFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQDYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000B4569A5 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura atramentaria TaxID=1990 RepID=UPI0003628776 +--SVERQLRRLEQRHHGRVGAYAIDTGTGRVL-GHRSDELFPVLSTSKAMTAAAVLRKAR +RDPGLLDRVVRYTRGDLVANSPVTEKHVGTGMTVADLCAAAITVSDNTAGNLLLRQIGGP +AGLTAFYRSLGDPVSRLDRWETDLNVWRPGERRDTTAPAAYARDLRTLTLGTALAPADRD +RLTGWMKATTTGGARIRAGLPKGWTVADKTGTGGYGTTNDVAVAWPPSGAPIVLVILTNR +RAADGAADEATVAETTAVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora coxensis TaxID=356852 RepID=A0A1C5JXB7_9ACTN +------QLAALERRHDARLGVYALDTGSGRML-AYRADERFAYASTFKALAAGALLAATS +--DADLDRVVRYGRKDLVPHSPVTEQHVAGGMTLREIADAALRHSDNTAANLILAELGGP +DGFERALRGIGDTVTDPARTEPDLNQAAPGDVRDTSTPRALADSLQAYAIGDALSVTDQA +VLLDWLKRNTTGATLIRAAVPAGWQVADKTGAGGYGTRNDIAVVWPPDSAPIVLAVLSRR +DSRDATHDDAVIAQATRVTLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009952061 +----NQAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADNRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPETITKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +NKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=C2UVK1_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1W5VPU9_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMEHG--------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A172WCF6_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQP +QLLQWMVDDRVAGPLIRSVLPAGWFTADKNGTGKRCARGIVALLGPNNQAKRIVVIYLRN +TAASMAERNQQIAGIGAALI--- +>[subseq from] class A beta-lactamase n=1 Tax=Cronobacter sakazakii TaxID=28141 RepID=UPI000CFAC511 +----------------------ELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B1DH22_BACCE +-----HSFVKLEKEYDAKLGIYALDTDTNQTV-TYRSDERFAYASTHKSLAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKNPIILAILSNH +SKEDVNYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF92319 +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVGWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. FJAT-26652 TaxID=1684141 RepID=UPI0009E993A8 +--HIDREFAQLESKFDARLGVYAIDTGKNRTV-AYRPNERFAYASTYKALAAGALLQHSS +--IDQLNELVTYNSQDIVSYSPITKLHVDTGMTLREVCEAAVRYSDNTAGNLLLKKLGGP +EGFETALRRIGDNVTRPDRYETDLNEAVPGDTRDTSTPRALATSLRAFAVSGLLPVEKRT +ILTDWMRGNATGDALIRAGAPKGWEVDDKSGAGSYGTRNDIAIVWPPHRAPIVIAILSTR +DTQNATYDNALITEAAQVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0005CF209B +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLDGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD118 TaxID=1053231 RepID=R8QI36_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRSNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0007ABB1D8 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYADKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. CNZ285 TaxID=2035250 RepID=A0A4Y9V878_9ACTN +-----AELAALERRFGARIGVFALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFARALREVGDSVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYALGETLPPADRD +LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR +DSRDAKPDDALVAQAARATV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI000A3732BD +-----EGFEKLEREFGARLGVYAVDTGTGREV-THNDRARFAYNSTFKALQAAVVLDTYS +--LDGLDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEQRDTSTPRALAEDLRAFVLGKALRAPERA +QLTAWLRTNTTGDAVIRAGVPKGWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000D035EDA +----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPKRFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPTEKRN +FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGAYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLN-- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1E8AKW3_BACTU +----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLEQRIKYTSKDLVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQDYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora haikouensis TaxID=686309 RepID=A0A0D0US04_9ACTN +-----AELTALERRFDARLGVYAVDTGTGRTL-AHRADERFAYASTIKALAAGALLAATS +--EAELDRVVRYDRADLVSHSPVTQRHVADGMTLRAVADAAVRHSDNTAANLMFTELGGP +AGLGRALRGIGDTVTNPARTETSLNEAAPGDLRDTSTPRAMAGSLRAYALGDALSAADRG +VLVDWLRRNTTGSTLIRAGVPAGWQVGDKTGAGGYGTRNDIAVLWPPEGAPIVLAVLSRR +DAKDAQPDDALIAEAARVTID-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. Hp2 TaxID=701189 RepID=UPI00112A6D71 +--DLAGRWAAIERESGGRLGVMLLDTAGGRRV-GHRQDERFPMCSTFKFLLAAAVLKQVD +AGKVGLDRRLPIQASDLVGHSPATGKHVGPDLSVAEMCQATLIWSDNAAANLLYPLVGGP +AGLIAFLRGIGDATTRTDRLEPMLNEFAPGDPRDTTTPAAMAGTLQRILLGDVLRPASRR +RLTDWLIDNRTGNARLRAGLPPDWKIGDKTGSNGEDTVNDIAILWPPGRPPLLLAAYLNG +AKVDAAGQDAALRAVAQAVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE153DC +--DIDKRLAALEARIGGRLGVSVLDSQTDVSF-GYRGSEAFAMCSTFKVLAAGYVLARVD +NGDEKLDRRITFGKDKLVSYSPETEKHAGGEMTMAEICKAGITLSDNTAGNLMLESFGGP +AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSILAEDSAN +QLVDWMVANTTGAARLRAGLPSGWRIGDKTGTGDDGSAGDIAIIWPPGRGPIVAAVYMAE +TTVKMDEFNPVFAEIGKMITE-- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 01375 TaxID=2203194 RepID=UPI000F7A073B +--QFHDRLMELEKKFDARLGVYALDTEGGSTV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVRYSREDLMKHAPVTGQHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +AALTAFTRSLGDTVTRMDRVEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTADKRD +FLRDLLQRNATGAERIRAGLPSGWTVADKTGTGDYGTLNDIAVLWPPAKAPIVLAIMSSK +AAKDAPYDQALLAEAAKYVAETf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI0004CB51EA +-----EGFEKLEREFDARLGVYAVDTGTGREV-THNDRARFAYNSTFKALQAAVVLDTYS +--LDGLDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEQRDTSTPRALAEDLRAFVLGKALRAPERA +QLTAWLRTNTTGDAVIRAGVPKGWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. AY18-3 TaxID=2217814 RepID=UPI0011CBFD90 +--AMYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A7HQ27_BACCE +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITYTKDGLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSERFETELNEAIPGDIRDTSTAKTLATNLKAFTVGNALPADKRK +ILTEWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces baarnensis TaxID=66872 RepID=UPI0004AB42C4 +-----EGFEKLEREFDARLGVYAVDTGTGREV-THNDRARFAYNSTFKALQAAVVLDTYS +--LDGLDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEQRDTSTPRALAEDLRAFVLGKALRAPERA +QLTAWLRTNTTGDAVIRAGVPKGWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Hyphomicrobium sp. (strain MC1) TaxID=717785 RepID=F8JDV0_HYPSM +-----NAFAGLEKQYGGRLGVAVVDTGSGERM-AYRADERFPMCSTFKLLIVGAVLHNVD +KGSERLDRWIPFQASDLLDYAPVTKTAVGNGMTMSDLCAAAIEYGDNTAANLILKAVGGP +DGATRYVRSLGDEVTRIDRFEPDANTCIPGDPRDTTTPAAMLADLKALVLGDALSANART +QLLGWLNGCKTAARRIPADLPAGWISGDKTGSGANGTANDVAIIQRPNKKPLLVAAYSTG +VAAKPADRDPMLADVGRIVARHf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus proteolyticus TaxID=2026192 RepID=UPI0008FE43CE +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IENLDQIIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRDIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI00061DB914 +----NKKLVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKNDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KSFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A420H5U8_9BACI +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-SYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +STFEKILRKIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSKKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. XY006 TaxID=2021410 RepID=A0A231PI70_9ACTN +--SVTARLRRLEREHTARLGVYARNLRTGRTV-AYRSDERFPMASVFKTLAAAAVLRDLD +RDGEFLARRIHYTRAYVTKYSPVTEQHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP +TAITRFARSVGDGVTRLDRWEPELNSAEPWRLTDTTTPRAIGLTYARLVLGDALAPRDRA +RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNHDVGITWPPDGPPIVMSVLTTQ +PEEDAPADNPLVAKTAALLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces albireticuli TaxID=1940 RepID=A0A1Z2KUZ2_9ACTN +-qEAERAFGELERTYDARLGVYAVDTGSGRTV-THRPDERFAYASVCKAFLAGAVLKKNT +--LQRLDRHVRYGRDVPVGHSPITGRHVDSGMTLRELCDAAVRYSDNGAANLLFDELGGP +KGLQEALAAIGDRVTRADRYETDLSEAAPGDPRDTSTPRAMAADLRAFVLGDALAADERS +ALTDWLKRNTTGDKLIRAGVPAGWQVGDKTGSGGYGARNDIAVLWPPRAAPIVVAVFSSR +TAKDAKADDTLIAKATEATVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8DX17_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLH-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BAG3X2-1 TaxID=1053183 RepID=J7UNL3_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQIV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCF868 +--DVDKQLGDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD +QGAEKLDRRVTYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAILDSIGLLTLGNTLSETSRD +QLVNWLVGNTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAPAKDVEEVFAEVSRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000E739AD7 +-----KKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTRANRFETDLNSAVPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGNYGTRNDIAIVWPPNRAPIILAILSNR +FTKDAHYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. YLB-04 TaxID=2259171 RepID=A0A3D8GQS0_9BACI +--QLHRKFAELENKYDARLGVYAIDTGTNRKV-SYRPQERFAYASTYKALAAGALLQQYS +--IDQLDELVTYNSEDIVSYSPVTQLHVDTGMTLGEVAEAAVRYSDNTAGNLLLEKLGGP +EGFETALRQIGDRVTQADRYETDLNSAVPGDKRDTSTPKALATSLQALAVSDLLPTEKRT +ILTDWMRGNATGDTLIRAGAPTGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR +DTQNATFDNTLIAEAAKVALN-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000CF38591 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPFMSTGKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLTTTIGGP +KELTAFMHNMGDHVTRFDRYYGELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Kroppenstedtia eburnea TaxID=714067 RepID=A0A1N7MLB9_9BACL +--AIKDDFAKLEEKFDARLGVFVLDTGTNQTV-TYRPDERFAYASTHKALAVGALLQQKS +--IEDLDQKITYTRDDLVDYSPITEKHVDTGMTLKELCDASLRYSDNTAGNLILEQLVGP +SGFKKSLRKMGDDVTNPERIEPELNEVKPGETQDTSTPKALATSLQAFTIGDVLPREKSK +MLTDWMKRSTTGDSLIRAGVPKSWEVADKSGAGLYGTRNDIAIIWPSKGDPIVLAVLSSR +EKKDAEYNDKLIAQATRVALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI00040E7229 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLETGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SM13 TaxID=1983803 RepID=UPI000CD53A41 +-----EGFEKLEREFDARLGVYAVDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS +--LDGLDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIRAGVPKGWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B0HK74_BACCE +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKTS +--IEDLDQIIKYTSKDFVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYNDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9DT24_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDLRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SDFKKSLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKRN +FLIELMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00115D8F82 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETALNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8FUH5_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLH-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000693B0B2 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMD----------------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000FFE0296 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FMKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0013772D13 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FMKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0003981537 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FMKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase class A/beta-lactamase class A TEM n=1 Tax=Enterobacter kobei TaxID=208224 RepID=A0A658UC36_9ENTR +-aDTLSAVKQAETTLAARVGYAELDLASGKVLgSYRVNERFPMMSTFKVLLCGAVLARVD +AGQEQLDRRLRWQKADLITYSPVTEKHLADGMTVAELCDAAITMSDNTAANVLLSTLGGP +QKLTAFLRKTGDAMTRLDRVEPELNEALPGDVRDTTTPVAMAKTLRQLLTGNTLSAASRQ +QLARWMEDDKVAGPLVRSVLPAGWYIADKTGAGERGSRGIVAALGPDGTPSRILVIYVTG +SSATMDERNKQIAAIGEAVIKQw +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6LHE7_9BACT +--DFANRIRSIEQRTGARIGVTALDTSSGKGI-DYRSEERFPMCSTFKFLAAAVVLKRVD +DRQEKLDRFVSYGAKDILEYAPVTKAHLKDGMILGALCAAAIEQSDNTAGNLLLDTIGGP +VGLTNFVRSIGDEMTRLDRKEPELNSAIPGDERDTTTPAAMCADIQRLVLDNVLSESSRH +QLEDWLRHNETGALMIRAGVPKTWTVGDKTGRCGNGATNDVAIIRPPGRAPVVFAIYSIG +STSSADDRAAIVADAARVVV--- +>[subseq from] Beta-lactamase n=2 Tax=Alloactinosynnema iranicum TaxID=1271860 RepID=A0A1G6S0Z8_9PSEU +----RHRLRELEADYPGRIGVSAFNTGDGRAI-AYRAGERFAIASTFKVLAAAAILRKAR +RDPGLLDRVVHYTRADLVPHSPITEKHVATGMTVARLCEATITHSDNTAGNLLLRELGGP +GAITAFTRTLGDHRTRLDRWETELNSAIPGDRRDTTTPGSMTRNLYALTLGHGLVRPDRE +RLTGWLLANTTGGGRIRAGVPSDWKVGDKTGTPAYGGVHDVAIVWPPDARPLIISVYTTR +TDPDTPGEERVVRDITRVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF0948A +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas axonopodis pv. begoniae TaxID=473403 RepID=A0A2S6YG25_9XANT +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPQMNRFAVGDPRDTTTPAAMAVTLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2C5CUY1_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEF881C +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis subsp. higo TaxID=132266 RepID=A0A243KYI6_BACUH +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar ostriniae TaxID=180883 RepID=A0A2C9YZ75_BACTU +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0007AB62F3 +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDISIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BED00D5 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD133 TaxID=1053233 RepID=R8EIA2_BACCE +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. mrc49 TaxID=2054913 RepID=A0A2M9NZH6_9BACI +-----QNFAQLEEKFDAKLGIFALDTGTNQTV-TYHPDERFAYTSTHKALAVGALLQQKS +--LEDLKQRITYTQEDLVNYNPITEKHVDSGMTLKELSDASLRYSDNTAGNLILKQLGGP +AGFKKVLEEMGDDVTSPERIEPALNEVNPGETHDTSTPRALAASLQAFTLGDALPKEKRE +LLLDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DEKDAEYNDKLIAEATKEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia speluncae TaxID=419477 RepID=UPI0012F4B651 +--ATTQAFADLEQTHGARLGVFAVDTGTGRSV-AHRPDERFPMASTFKGLACGALLHEHP +LSSGFFDRVIHYPPHELVEYSPVTEQHVGTGMTVAELCHAAITVSDNTAGNQILKLLGGP +AGFTAFLRSIGDDTSRLDRWETELNTAVPGDERDTTTPAALAAGYRTLVVGDALQVPERE +QLKSWLIATSSGEDRIRAGLPADWTVGHKTGTPAYGSALDVAIAWPPGRAPLVIAVLSTK +PEQDAEPDSALLAAATRAAVA-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0011556E05 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIADATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A679HBC8_9BACI +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFCE390 +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRYSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPQNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C2VEQ6_BACCE +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDLRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKTLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKQN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Actinorugispora endophytica TaxID=1605990 RepID=A0A4R6V2V7_9ACTN +----EREFERLEGEFDARLGVYAVDTGSGDTV-AFNADERFAYASTHKAFSVGALLRQNS +--IEELERVVTYTEDDLVGHSPVTRRHVETGMTLREISDAAVRYSDNTAANLLFEELGGP +EGLDAALEEIGDDVTHVDRIEPDLSDWEPGDIRDTSTPRAMATTLRAYTLGDALPEEKSA +ILIDLMKRNLTGDALIRAGVPDGWEVGDKTGNANYGTRNDIAVLWPPNGDPIVLAVMSSR +DAEDAEHDDALIAEAAEVVVD-- +>[subseq from] Beta-lactamase n=3 Tax=Xanthomonas citri TaxID=346 RepID=D4T6V4_XANCI +--MLRARWAQIERGTGGRLGICLLDSATGKRL-GQREEERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSIGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGVGDAQTRTDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGGPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. FT14W TaxID=2654253 RepID=UPI0012654069 +--TAQTQLAALEQAAGGRLGVAAWRHGSELRV-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLDQPVRYEKKELVTYSPITEKHLADGMTVAELCAATLQYSDNSAANFLMKILGGP +QAVTAYARSIGNTLFQLERWETELNSAIPGEVRDTASPTSMAHSLQQLLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATRIVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BAG6X1-2 TaxID=1053195 RepID=J8B7I0_BACCE +----YKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKAVAAGVLLQQNS +--TDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIAINLKAFTVGNALPDHKRN +ILTEWMKGNATGDKLIRAGVPTDWGVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEIIVN-- +>[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI0011F01728 +-tEMKDDFAKLEEQFDAKLGIFALDTDTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVMK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9PFS5_BACCE +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKTS +--IEDLDQIIKYTSKDLVNYNPITEKYVDAGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRDIGDTVTNPERFEPELNEVRPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYNDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A1A9PU86_9BACI +----NDSFTKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWDVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium sp. WSM3868 TaxID=2029405 RepID=UPI000BAEF35C +---ATKAVEALEARNGGRLGVMILDVGTNAAI-EYRADELFPMTSTFKFLAAAGVLKAVD +DGKAKLDDRIVYAASDVEPYSPVTKEHSGEGMTLEDVCAAAVVWSDNTAGNLLLRVLGGP +QGLTRFARTLGDDVTRLDRTEPTLNTAIPGDKRDTTSPRALLGDARRILLGDALSPASGK +RLEAWLIEDKVGAARIRAGLPATWGIGDKTGSGDNGTTNIVAILWPPEGAPILAAVYYTG +STAPRASREAVHADVARIIVETf +>[subseq from] CRH family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=UPI0005B7B9B2 +----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPLCSSFKGFLAAGVLAQSQ +DKPGLLDKRIRYSKAALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLKEINGP +AALTTFMRSIGDASFRLDRLEPELNSAIPRDPRDTSTPKAVAESAQKLALGKALPEPQRQ +QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH +AKKEAKHSDEVIAAAARAALEAf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1S9U3L9_BACCE +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDIGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIMLAILSNH +AKEDAKYDDKLIADATKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000A37C554 +-----DSFAKLEKEYDAKLGIYALDTVTNQTV-SYRSDDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTRKDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTNSERFEPELNEVNPEETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIVWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKIVLN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1S9T583_BACMY +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASSHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF3D7A5 +----NQSFAKLEKEYDAKLGIYALDTGTNQIV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BFE6DA6 +----NQSFAKLEKEYDAKLGIYALDTDTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQKITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFE2A17 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVNTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=6 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2A7C2G9_BACCE +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0005CA249E +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVNTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=C8CE58_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQ------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8X4_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMVDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. BK696 TaxID=2512157 RepID=A0A4Q7T177_9RHIZ +-dDVDQQLAALEKRTGGRLGVSVMDTGTNVSF-SNRETERFPLLSTFKVLASGMVLARVD +KGEENLERRVTYDQDKIVTYSPETEKHVGAEMTVGELCKAAITLSDNTAGNLLLESLGGP +EELTKWLRSIGDTSTRLDRIETALNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLSEPSRT +QLIDWMVANTTGAARLRAGLPEEWKIGDKTGTGNNGSAADIAVLWPESGSPILVATYIAE +ATAPVSELNEVFAEVAKIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cavernae TaxID=1674310 RepID=A0A433HUH2_9BACI +--HIHREFVDLESKFDARLGVYAIDTGTNRIV-SYRPNERFAYASTYKALAAGALLQHYS +--IDKLDELVTYKSEDIVSYSPVTQLHVDTGMTLREVIEAAVRYSDNTAGNLLLEKLGGP +EGFESALRQIGDNVTQVDRYETDLNSAIPGDKRDTSTPKALATSLQAFAVSDLLPTEKRT +ILTDWMRGNTTGDALIRTGAPTGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR +DTQNATYDNTLIAEAAKVALN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillaceae TaxID=186817 RepID=N1LLK2_9BACI +-qETYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDNGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Moraxellaceae bacterium TaxID=1889775 RepID=A0A4Q5VNW2_9GAMM +------FLAQLETQAQGRLGVSAINTATQQRI-DYRASERFPLCSTFKLIAVAAILHKSM +HSPNLLQQRMQYSMQQVKDYAPITSQHVDTGMTVSELCAACISYSDNTAANLLLQILGGP +AALTQFARSIGDPAFRLDRWEPALNTALPNDVRDTSTPAAMADTLQRLLVSNVLADTQRA +LLLYWLKNNTTGNARIRAGVPKDWVVGDKTGTGAYGTSNDIGIIWPAQQAPIIVAIYFTT +PLKTAKPNDPVIAAVSRIMSQVw +>[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI0008FAE233 +-tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-TYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALATSLQAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVLEGWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A3D9UT12_BACMY +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIILAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. Root1204 TaxID=1736428 RepID=A0A0Q6S5T8_9RHIZ +-nDIEQQLTALEKRTGGRLGVYVLDTKTKASF-AHRPDERFAMCSTFKALAAAFALARAD +KVEEKLDRRIPISKKHLLSYSPIVEKHVGGGMTVRELCDATVRYSDNAAGNLLLASFGGP +KGLTDWLRSIGDETTRLDRIEPELNEAKIGDPRDTTSPKAMTETLGKLLIGDVLSPASRD +QFSAWLVANTTGDRRLRAGLPKDWTIGEKTGTSGRGEAGDIGFMRPAEGHTILASVYIAE +GTKPTKELEPVFAEVGKLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SDLI1 TaxID=1774743 RepID=A0A109WEL2_9BACI +---TNKKFVQLEKKFDARLGVYAIDTGSNKTI-TYRPNEQFAYASTYKVLAAAAVLKTSS +--NEKLNDIIRYTKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHLTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR +FTEDANYHNALISEAAKAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. NH11B TaxID=1866314 RepID=UPI0008FDA957 +----NQSFVKLEKDYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQIIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRDIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q6ZY53_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIA---------- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora tulbaghiae TaxID=479978 RepID=A0A1C4XUN8_9ACTN +-----AELAALERRSGARIGVFAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DAERDRVVRYRRVDLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFERALREAGDRVTRPARAEPELNAATPGDERDTSTPRAMAGSLRAYALGEALPPADRD +LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMTSR +DSRDAEPDDALVAQAARATV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B2LJH7_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKNGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNGLPDHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. AY18-3 TaxID=2217814 RepID=UPI0011CA4EC5 +----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTRKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPKRFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGAYGTRNDIAIIWPPNKKPIVLAILSNH +TKEDAKYDDKLIADATKIVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus aidingensis TaxID=384933 RepID=UPI00047CB7E3 +---MTDDFAELEDEFDAKLGVFALDTGTNETV-TYRPDERFAYASTFKVLAVGALLQQKS +--IADLNQRITYTRDDLVNYNPITKKHVETGMTLKELCDAALRYSDNTAGNLIFEQLEGP +GGLKKSLREIGDQVTNPERIEPELNEFKPGETQDTSTPKALADSLQAFTMGDVLPSEKRT +MLIDWMKRNTTGDTLIRAGVPESWEVADKSGAASYGTRNDIAIIWPPEEDPIILAILSRR +GKKDAEYNDELIAQAAEEVID-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. (strain 4-46) TaxID=426117 RepID=B0UJG8_METS4 +----VARLAALERHDGGRLGVTVRDTGTGRIL-SYRADERFPLCSTFKAVAAAAVLARVD +RGEESLDRRMAYGPEDLDAYAPETRRRVGEGIDLRAACAAAVIWSDNTAANLMLRALGGP +EAVTAFARAQGDAVTRLDRTEPSLNTAIPGDPRDTTSPAAMAALMERILVGPVLSAESRA +LLLGWMTQSPTGAERLRAGLSPGWQVADKTGTGANGTANVVALVRRPGGAPLVASVYLTQ +SPAPAEARNGLHAEVGRLVARTf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD048 TaxID=1053226 RepID=J8I825_BACCE +----NQSFVKLEKDYDAKLGIYALDTGTNQIV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDTKYDDKLIANATKIVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009ABFB74 +----YKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKAVAAGVLLQQNS +--TDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIAINLKAFTVGNALPDHKRN +ILTEWMKGNATGDKLIRAGVPTDWGVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEIIVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0010C2DABB +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDISIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. CNZ296 TaxID=2572906 RepID=UPI0011A627F0 +------ELAALERRSGARIGVFALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFERALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD +LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR +DSRDAEPDDALVAQAARATV--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas euvesicatoria TaxID=456327 RepID=UPI0006E4FAA7 +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRVD +QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP +AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPSDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTASWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus siamensis TaxID=659243 RepID=A0A2K9KDG8_9BACI +---TNKKFVQLEKKFDARLGVYAIDTGSNKTI-TYRPNEQFAYASTYKVLAAAAVLKTSS +--NEKLNDIIRYTKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHLTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR +FTEDANYHNALISEAAKAALD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0011A6496D +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTSGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001298A642 +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREMGDTVTNSERFEPELNEINPGETHDTSTPKAIAKTLESFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH +DKEDAEYDDTLIADATKIVLE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8XHB2_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF3CDC6 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B6RSD3_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. SM1 TaxID=429004 RepID=UPI0009FD6AB6 +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLESFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPRGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH +DKEDAEYDDTLIADATKIVLE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF6F8A3 +----DNSFAKLEKEYDAKLGIYALDTGTNQTV-SYRSDDRFAFASTSKSLAVGVLLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPVVLAILSNH +DKEDAEYDDKLIADATKTVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEEE536 +---LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD +RGELTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP +AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK +QLTDWMIHNRTGDTCLRAGLPRGSKIGDKTGSNGSDTRNDIAIIWPSAGAPLLLTAYLNG +ASVDSDARDAALKAVAAAVRD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00053401FE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVLVK-- +>[subseq from] Beta-lactamase (Putative hydrolase) n=1 Tax=Bacillus sp. 71 TaxID=593090 RepID=A0A653V7Z3_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVNTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRA +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2C4FLM5_9BACI +----NHSFVKLEKEYDAKLGIYALDTSTSQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDFVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWIVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001427BA2F +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAITKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH +DKEDAEYDDTLIADATKIVLE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8CIW9_9BACI +hqATYKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLLVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI0011BDA006 +-tEMKNDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVMK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Moraxellaceae bacterium HYN0046 TaxID=2283318 RepID=A0A345PBP9_9GAMM +---LTQELTALETSSKGRLGLALINTGTGQEF-QYRGDERFPFCSTFKLMLASAVLKKSM +TQASLLTQHIAYSEEDLLSYAPITRKNLAQGMSVSELCAATLQYSDNTAANLLIKQIGGL +EAVNHFAQSLGDRDFRLDRFEPDLNSALPFDIRDTTTPKAMANSLKKIALGNILAPNLRA +QLITWIKGNTTGDATIRAGAPSGWKVGDKTGSGNYGTTNDIGLLWPPSGEPVVLTIYFTQ +LKKDADNRRDVLAAATKLALSHy +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFB852B +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAASALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces prasinus TaxID=67345 RepID=A0A5J6H705_9ACTN +------DFEELERTYGARLGVYAVDTGSGREV-THNDDERFAYASTFKAFAAAAVLREHS +--PSGMDEVITYSGDDLVAHSPVTEKHVGTGMTLRELCDAAVRHSDNTAANLLFDALGGP +KGLASALEEAGDTVTRVERREPELNQWAPGSTRDTTTPRAWADALRAFVLGDALDGKERA +QLTKWLRTNTTGDALIRAGVPEGWVVGDKTGGGGYGVRNDIAVVWPPDAAPLVMAIMSNR +RTADAGYDDELIAEAASVVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. HDW3 TaxID=2714923 RepID=UPI001408A4FB +--------QAIEASSQGRLGVAVLNTHSGRLT-GHRLDERFPMCSTFKWLAAAHVLQRVD +QGLEQLERQIPFGPEALLHWSPVTERHADGNMTLAALCHAAITESDNAAANLILHTLGGP +KGLTQFARQLDDPVTRLDRWEPELNEATPGDARDTSSPRAMAGLLQRCVLGDALSARSRA +QLTQWLRGTRTNTARLAAQMPADWRVGSKTGTGGHGTTNDVGIYWPAGHAPLVVAAFLTE +SAASLQTREAALAQVAHAA---- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. Root627 TaxID=1736572 RepID=A0A0Q8E6E6_9GAMM +--DATAQFTELERKHGGRLGVSILDAQSGRRI-RHRAGERFLMCSTFKWLAAAAVLARVD +SGRERLDRRVVYGKDVLLDYAPVTSKHVGAPLSVAELCAAAVTLSDNTAANLLLASMGGP +TAITAFARSLGDETTRLDRIEPELNLGSPGDIRDTTTPDAMLADLHRVLLGDRLSAGSRD +LLLQWLRGCSTGLDAIRAGLPANWTAGDKTGSGSQGETNDVAIIWPPRRKPLLVSAYYAG +SHAEPAERKAVLAAVGRIAA--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2B5VEU4_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAAAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Betaproteobacteria TaxID=28216 RepID=UPI00036DDC55 +----AAQLARLEADTRGRLGVAAVNTADGRIL-SHRGDERFPLCSSFKAMLAAAILQHEP +---SLLDKRIRYTAADLVSHSPVTEQNLADGMTVGELSAATIQYSDNAAANLLMKQIKGP +AGVTAYARSIGDKAFRLDRWETELNTAIPGDPRDTTTPLAMMKSLQSVTLGPALTVDKRK +LMTEWLIGNTTGDTRIRAGVPYDWQVGDKTGTGSYGSTIDIGVVWPPGKAPVVMALYYTQ +PGKDDKANPEILASAARVVVEAf +>[subseq from] Beta-lactamase n=2 Tax=Nocardia farcinica TaxID=37329 RepID=A0A0H5NMB1_NOCFR +--AATAEFAALEQRFGARLGVYAVDTTSGAEV-AYRADERFGMASTFKGLACGALLREHP +LSSGYFDQVVRYSREEVVSYSPVTETRVDTGMTVAELCHATITVSDNTAGNQILKLLGGP +AGFTAFLRSLGDEVSRLDRWETELNEVPPGEERDTTTPAAVAANYRALVLGDVLAEPERA +QLRDWLVANTTGDQRIRAGVPAGWTVGDKTGGGSHGGNNDVAVAWTETGDPIVIALLSHR +TDPAAKADNALLAEATRAVVT-- +>[subseq from] Beta-lactamase n=2 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=A0A379MC39_RHORH +--AATAEFAALEQRFGARLGVYAVDTTSGAEV-AYRADERFGMASTFKGLACGALLREHP +LSSGYFDQVVRYSREEVVSYSPVTETRVDTGMTVAELCHATITVSDNTAGNQILKLLGGP +AGFTAFLRSLGDEVSRLDRWETELNEVPPGEERDTTTPAAVAANYRALVLGDVLAEPERA +QLRDWLVANTTGDQRIRAGVPAGWTVGDKTGGGSHGGNNDVAVAWTETGDPIVIALLSHR +TDPAAKADNALLAEATRAVVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI0005ED1C9E +---SDRQFAKLEDKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVGTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDNVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPAEKRE +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 196mf TaxID=1761754 RepID=A0A2V4X4V1_9BACI +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTTGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] BES family class A beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=UPI000FEB99C0 +--ELDSALARLEQQHHGRLGLAYIDSGSGESY-SYRGEERFAFCSTFKAVLAGAVLQQSV +SQPGLLDKQVHYAATDLLAYAPITKTHLDKGMRIGELAAAAVQYSDNTAANLLLQEIGGV +QALNRFVQGLGDPAFRLDRIEPHLNSAEPGDVRDTTTPLAMAHTLQAMTLGKGLPQAQQA +QLVSWLKGNTTGAQRIQAGVPAGWQVGDKTGTGGYGTTNDIAILWPEQGAPKVLAIYFTQ +PAANAQANRAILAEATRLVLQ-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2T0EGZ3_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHQDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0B4ZW49_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDE---------------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF00F7B +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGKTHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI000C7E44A1 +--DVTERLRQLEERTGGRLGVAVLDMETNISF-GYRETERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTIAELCEAAITISDNAAGNLLLESFGGP +QGLTSWLRSIGDNTTRLDRTEPDLNEARKGDPRDTTTPAAMLDTLGKX-LGSVLSENGRG +QLVDWLVANETGDARLRAGLPKDWRIGDKTGTSSTGAVSDIALAWPPGRGPLLVAVYTGE +AKAPVSDLNPVFAEIGKIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00142E7D11 +----NKKLVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPVTEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQVGDQVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FTKDANYNNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00141B4CF4 +--ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD +KGELTLGKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGDALQAASRK +QLTEWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG +ATVDAAARDAALKAVAAAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00141B4F34 +--ELREAWAGIEHRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD +KGELTLGKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPEAMAATLRTLLLGNALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG +ATVDAAARDAALKAVAAAVA--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=S3I4V9_BACCE +----SQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2B3FJ34_BACTU +----SQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudonocardia sp. 73-21 TaxID=1895809 RepID=A0A1Q4DLM6_9PSEU +------RLADLERRFDARVGVFAIDTGTGTTV-AHRADERFAMCSTHKALVAGAITLRGD +-----LDRRITYTRAELVPYSPVTGTNVTAGMTLGQLCDAAVRHSDNTAANLLVRELGGP +AAVTAFARTLGDDVTRLDRTEPDLNEATPGDPRDTTTPRAIAADLRAMALGPALPEAGRA +ALTGWLVGATTGAGRIRAGVPGGWTVGDKTGSGGYGTANDIAVLWPPTGAPVVLAVLSSR +PTQDATSDPALLAQATTIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Methylophaga aminisulfidivorans MP TaxID=1026882 RepID=F5SX75_9GAMM +---WQDEVTQLETIYGGRIGVSAWNANDGQQL-HYRENERFAMCSTFKLLLVANVLQRID +QKQEKLERLISYDKSEILEYAPVTSQHLDKGMTVADLSKAALQLSDNTAANLLLNTLGGP +QGLTDYLRSLGDNTTRLDRIEPNLNTNLAEDPRDTTTPKAMLLTLKTLLLGDTLSEASKQ +RLIHWLIGNQTGDDKIRAGVPATWLVGDKTGSGANGANNDVAIIWPEAGHPYLLIVYYSG +SERSKNEKNAVIAKISQSVSKVf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1ZGP9_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHIDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGNALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Pleomorphomonas oryzae TaxID=261934 RepID=UPI00040078B5 +--KADDEFAKLEKQSGGRLGVAAVDKASGKRI-AYRADERFAMCSTFKFLAAAAVLARVD +KGELKLDKSIAYGKDDLLSYAPVTKAHVAEGLTLEALCAAAVGVSDNTAANLLLKEIGGP +AGWTAYARTLGDTTSRLDRTEPELNSAVTGDARDTTTPAAMLANLDTVMIGDALKETSRD +KLEDWMVAGTVTGPLIKAGVPKTWQVADKSGSGANGTRNDIGVLYRPNTAPILAAIYTTG +SPLDMKGQNKVIADAAALIAARf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces variegatus TaxID=284040 RepID=A0A0M2GRS4_9ACTN +----TARLREIEREHTARLGVYARNMRTGRTV-AYRADERFPMASVFKTLAAAAVLRDLD +RDGEFLARRVHYTQEYVTKYSPITEDHVATGMTVGELCDATIRFSDNTAGNLLLEELGGP +TAITRFARSAGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGDALQPRDRA +RLTDWLLRNTTSGEKFRKALPADWLIADKTGGGRYGGNNDVGVTWPPDGPPIVMSVLTTQ +PEEDAPADNPLVARTAALLA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKI3_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLRGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYTTG +SQATMDERNRQIA---------- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2B7HEQ7_BACTU +-----DSFVKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTGKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5LVR2_9BACT +--EFENRVATIEARTGGRIGVAALDTASSKHL-DCRSEERFPMCSTFKFLAAAAVLKRVD +EKQEKLDRFVPYDAKDILEYAPVTKIHLKEGMTLGALCAAAIEQSDNTAGNLLLDAIGGP +IGLTNFARAIGDKVTRLDRKEPELNSAIADDERDTTTPAAMLADMLQLLLGNTLSPSSRH +QLEQWLQANQTGASMIRAGVQTSWIIGDKTGRGANGATNDIAIMRPPGRAPILLVIYSAG +STATANDRAAVLAEAAKIVT--- +>[subseq from] Beta-lactamase n=8 Tax=Bacillus TaxID=1386 RepID=R8JUT8_BACCE +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKATAKTLESFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH +DKEDAEYDDTLIADATKIVLE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00119C929D +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKTLREMGDTVTNSQRFEPELNEVNPGETHDTSTPKATAKTLESFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEIADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH +DKEDAEYDDTLIADATKIVLE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA3-9 TaxID=1053205 RepID=R8DA28_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IDKLNEVITFTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000D02772A +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLNEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus aryabhattai B8W22 TaxID=1358420 RepID=A0A1G6TF53_9BACI +---SDREFAKLEDKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDNVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPAEKRE +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGEPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Diaphorobacter sp. HDW4A TaxID=2714924 RepID=UPI001407E423 +--------ADIEAQSTGRLGVAVLDTASGHWD-GQRLDERFPMCSTFKWLAAAHVLQRVD +QGREQLERRIRFGRDALIEYSPVTESQAGKNMTLAELCHAAITVSDNTAANLILDTLGGP +QGLTAFARSLGDDVTRLDRWEPALNESKPGDPRDTTSPRAMATLLQQLVLGDALSSGSRE +QLTRWLQATTTNRGRLAADLPTGWKIGTKTGSSGNGSVNDVGVFWPPHRPPIIAAVYITA +GKGSSKSIEPAIATVARRIT--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A4U2ML01_9BACI +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRNSDNTAGNILFNKIGGP +KEYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=A0A2B9N7G6_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEQHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=BLAC_BACLI +-tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVMK-- +>[subseq from] Beta-lactamase n=1 Tax=Arenimonas donghaensis DSM 18148 = HO3-R19 TaxID=1121014 RepID=A0A087MJ51_9GAMM +-----DALRALEGRHGGRLGVFALDTGTGRTL-GQRGGERFAMCSTFKLPLAAQVLAAVD +AGRERLDRRLTWTPDDLVSWSPVVEKHDGAALAVDALCEATMTISDNTAANLLLAEHGGP +AGLTAWLRAIGDEVTRLDRNEPALNEATPGDPRDTTTPAAMVATLHKLLLGDVLSDASRS +RLTGWALANQTGDKRLRARLP-GWRVGDKTGTNNVGNSNDIGILWPPDRAPILVAAYYAE +SSGTPAERDTVLADVGHIV---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. AR2-1 TaxID=2217816 RepID=UPI0011ED97F7 +----NQSFAKLEKEYDAKLGIYALDTDTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Desmospora sp. 8437 TaxID=997346 RepID=UPI000300B1DE +--AIKDDFAKLEEKFDARLGVFALDTGTNQTV-TYRPDERFAYASTHKALAVGALLQQKS +--IEDLDQKITYTRDDLVDYSPITEKHVDTGMTLKELCDASLRYSDNTAGNLILEQLVGP +SGFKKSLRKMGDDVTNPERIEPELNEVKPGETQDTSTPKALATSLQAFTIGDVLPREKSK +MLTDWMKRSTTGDSLIRAGVPKSWEVADKSGAGLYGTRNDIAIIWPSKGDPIVLAVLSSR +EKKDAEYNDKLIAQATRVALD-- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacter segnis (strain ATCC 21756 / DSM 7131 / JCM 7823 / NBRC 15250 / LMG 17158 / TK0059) TaxID=509190 RepID=D5VMW0_CAUST +-kDLSSRINELEKASGGRIGLAVLDTHDGRRF-AWRGDQRFRMCSTIKAPLSAAILRRVD +QGRERLDRRVTFGPEVLMDNSPIVEKHVQDGMTIGQLCEATITLSDNAAANLLFEALGGP +AALTRFLRAIGDQTTRSDRLEPELNRGPPDDPRDTTTPAAMLATWKTLLLDDALSPASRQ +QFRDWLIANKTGDRRLRAGLPPGWRVGDKTGNNGRDITNDVAIAWPPGRGPILIAAFHDR +GG-DEAARNAVHANVARAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A4Q9Y9J1_BACMY +----NQSFAKLEKEYDAKLGIYALDTSTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1S9TQE9_BACCE +----NQSFAKLEKEYDAKLGIYALDTSTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2A9VJR0_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETALNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A4R3SCC8_9BACI +----NQSFAKLEKEYDAKLGIYALDTSTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000E1F3818 +--ELRDEWARIERRSGGRLGIGLLDSATGKRI-GQREDERFPMCSTFKFVLAAAVLQRVD +QGALTLAQRVKIRASDMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDACLRAGLTRDWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAGRDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF85621 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVL--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A150CSG1_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKYVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILKEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAVVWPPNREPIIIVILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-340 TaxID=1463901 RepID=UPI00056941AF +----VDELRALEERYAARLGLYARNARTGQTL-SHRAGERFAMCSTFKAFAAAAVLRDHD +-RCAPLDKVVHYPPADVLDNSPITKDHVDSGMTVGELCAAAIQYSDNTAGNLLLRELGGP +AGLTRFFRSLGDRVGRLDRWEPDLNTAVPGDPRDTTTPEAIATSLERVTLGRALTGGDRE +QLVTWLKGNTTSAERFRRGLPKGWVVGDKTGTGDYASANDIGVAWTTRGTPVVLAVLTSK +PAKDAAVDNALVAEAAGLVA--- +>[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. Ad13 TaxID=989396 RepID=UPI0007B26393 +-----DTVSQLETEVGGRIGVVLRHTGSDWTV-EHRADERFPMASTFKALLCGAVLSRVD +RGEESLGDLVTYKATELVSYSPVTENHLASGMSVGQLCEATVTMSDNSAANLLLKRVDGP +EGLTRFLRGLGDRVTRLDRNEPAMNEARRGDPRDTTSPSAVLKTLDRLLFEDVLLPSSRA +QLQQWMVDDKVADELIRKHLPKDWRIADKSGAGHNGSRGIIGVIWPETGKPYLAAAYMMG +SDASFKQRNAVIAEIGKAMIE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis MC28 TaxID=1195464 RepID=K0FHY0_BACTU +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQKITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Methylophaga sulfidovorans TaxID=45496 RepID=A0A1I3ZI98_9GAMM +--AWQDDVAQLETVYGGRIGVSAWNTNDGQQL-QYRENERFAMCSTFKLLLVANVLHRID +QKQEKLDRLISYDKSDILDYAPVTSQHLDKGMTVAALSKATLQLSDNTAANLLLNTLGGP +QGLTSYLRTLGDDTTRLDRIEPNLNSNLADDPRDTTTPEAMLFTLKTILLGDALSESSKQ +RLIHWLIGNQTGDDKIRAGVPSTWLVGDKTGSGANGANNDVAIIWPDAGQPYLLVVYYSG +SERSKSEKNMVIEKISQSVSKAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8W4_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGHEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIAVKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. DCY113 TaxID=2603818 RepID=A0A5B0H6F1_9BURK +--AIREQLARIEAGSGGRLGVSIVDTTSSLHA-GLRSDERFPMCSTFKLLAAGAVLTRVD +RGEEDLQRRVVFSERDLVPNSPGTRRHTRELMSIAELCKAALTLSDNTAANLLLASFGGP +AAVTAFARSLGDGITRLDRIEPMLNDATPGDPRDTTTPNAMLGNLRELALGEHLSRSSRA +QLLAWLAANETGGARLRAKLPQDWGVGDKTGTGEHGTANDIAILWPPGRGPVLVTVYLTG +TDGDAARSNAAIASVAALVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFB6766 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEQHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Class A beta-lactamase n=2 Tax=Bacillus subtilis TaxID=1423 RepID=A0A6A8FKA9_BACIU +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKNANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF1E94C +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKDLADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=A0A1E8PRG1_9BURK +--AAQTQLAALEQGAGGRLGVAAWRHGSAQRI-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLEQRVRYEKKELVSYSPITEKHLAEGMSVADLCAATLQYSDNSAANFLMRLLGGP +QAVTAFARSIGNTLFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLEHSLPAVQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKNADTNEDIITAATRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009B55BB0 +----NKEFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKNANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. LM6 TaxID=1938606 RepID=A0A1S6F388_9BURK +--AAQTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMNVAELCAATLQYSDNSAANFLMTILGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAAQRQ +QLDTWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLIIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA2-9 TaxID=1053204 RepID=R8CTG7_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILRDMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rubrivivax gelatinosus TaxID=28068 RepID=UPI0002FAE015 +------AFGAIERSVAGRLGVWAYDLETGRSL-GHRQDERFPMCSSFKWLLAAAVLARVD +RGQERLERRIVFGREALLEYAPATSRRAGGAMTVAELCEAAVTLSDNTAANLLLDTLGGP +AGLTAWVRMLGDRTTRLDRREPDLNEARPGDERDTTTPQAMVLALRQVLFGGALSRRGGD +LLLQWMVASTTGAKRLRAGFPADWRIGDKTGTGGQGTTNDVAVVWAPGRAPLLLAAYLTE +SQAAIEAREAALARVAG------ +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00022BA80D +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFALDNSLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Ramlibacter tataouinensis (strain ATCC BAA-407 / DSM 14655 / LMG 21543 / TTB310) TaxID=365046 RepID=F5Y501_RAMTT +--KAQAGWRDLEATVGGRLGVAVLDTADGRLD-GHRLDERFPMCSTFKWLAGALVLHRVD +AGQERLDRRIRFGREVLLPHSPVTGEHAGSQMTLAALCEATIATSDNAAANLILRSFGGP +AALTGYVRGLGDTMTRLDRWEPELNEATPGDPRDTTTPRAMAGALRAALVGEALSPRSRE +QLGRWMEATVTNGQRLRAGLPAGWRMGSKTGSGARGTTNDVGIFWPPGRPPVIAAVYLTE +TQAPDGARNAVIAGVARQL---- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia sp. FDAARGOS_372 TaxID=2018066 RepID=A0A2A7UAA3_9NOCA +--AATAEFAALEQRFGARLGVYAVDTTSGAEV-AYRADERFGMASTFKGLACGALLREHP +LSSGYFDQVVRYSREEVVSYSPVTETRVDTGMTVAELCHATITVSDNTAGNQILKLLGGP +AGFTAFLRSLGDEVSRLDRWETELNEVPPGEERDTTTPAAVAANYRALVLGDVLAEPERA +QLRDWLVANTTGDQRIRAGVPAGWTVGDKTGGGSHGGNNDVAVAWTETGDPIVIALLSHR +TDPAAKADNALLAEATRAVVT-- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6HF77_9BACT +--DAADQIAAIEARLGGRIGVAGLDTGNGKRI-DYRAEERFALCSTFKFLAAAAVLKRVD +EKKEKLDRFVSYDAKDILEYAPVMKAHLKDGMTLGGLCAAAIEQSDNTAGNLLLEAIGGP +AGLTNFARDLGDRVTRLDRKEPELNSAIPGDERDTTTPASILADVRQLLIGNPLSASSRQ +QLEAWLRANETGAAMIRAGISTNWIVGDKTGRGANGATNDIAIVHPPDRAPILLAIYCVG +TSASANDRAAAVAEAAKVMAESf +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora haikouensis TaxID=686309 RepID=UPI000B881C79 +-----AELTALERRFDARLGVYAVDTGTGRTL-AHRADERFAYASTIKALAAGALLAATS +--EAELDRVVRYDRADLVSHSPVTQRHVADGMTLRAVADAAVRHSDNTAANLMFTELGGP +AGLGRALRGIGDTVTNPVRTETSLNEAAPGDLRDTSTPRAMAGSLRAYALGDALSAADRG +VLVDWLRRNTTGATLIRAGVPAGWRVGDKTGAGGYGTRNDIAVLWPPEGAPIVLAVLSRR +DAKDSQPDDALIAEAARVTID-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia farcinica TaxID=37329 RepID=A0A449HCB6_NOCFR +--AATAEFAALEQRFGARLGVYAVDTTSGAEV-AYRADERFGMASTFKGLACGALLREHP +LSSGYFDQVVRYSREEVVSYSPVTETRVDTGMTVAELCHATITVSDNTAGNQILKLLGGP +AGFTAFLRSLGDEVSRLDRWETELNEVPPGEERDTTTPAAVAANYRALVLGDVLAEPERA +QLRDWLVANTTGDQRIRAGVPAGWTVGDKTGGGSHGGNNDVAVAWTETGDPIVIALLSHR +TDPAAKADNALLAEATRAVVT-- +>[subseq from] Beta-lactamase n=1 Tax=Allokutzneria albata TaxID=211114 RepID=A0A1G9UHZ2_9PSEU +-----PDFTALEKQFGARLGVFAIDTATGKTV-SHRENDRFAMASTFKAYAVAALLKRHG +--TEVLSKRVHFTQQEIVTYSPVTEKHVGTGMTVGELCGAAITKSDNTAGNQMLKLLGGP +GELTKFAKSIGDGTTRLDRWETELNTAIPGDERDTSTPKALGSAYRDLVVGDVLPPAERE +QLKKWLLTNTTGGERLRAGIPKEWSIGEKTGTGDYASANDVGVAWTEKGTPIAIAVLTTK +DTKDAKADNALLARTAKLIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycetocola sp. 449 TaxID=2079792 RepID=UPI000D3D72A9 +--SADAEFDELEQKFDARLGVYALDTGTGLAL-EYRSDERFAYASTIKVVASAVLLDQTS +--DDELDTLVTYDESDLLDYAPITEQHVDTGMTLRELGDAAVRYSDNTAANLIFEQIGGP +AGLAAALTAMGDDVTQVDRIEPDLNEATPGDPRDTTTPEAFATTLEALVLGDALEASDRE +LLTEWLVGNTTGDKLIRAGVPTEWTVGDKTGSAGYGTRNDVAVIWPREGDPIVLTVLSSR +SEADADYDDALIAEATAVAIE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00115C29A4 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGIRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas axonopodis TaxID=53413 RepID=UPI0009965D3E +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGVGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG +AKVNDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9DP81_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAYNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. BRIP62411 TaxID=2182389 RepID=UPI000F8C3461 +--ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD +KGELTLGKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGDALQQASRK +QLTDWMIDNRTGDTCLRAGLPRGWNIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG +ATVDAAARDAALKAVAAAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar cameroun TaxID=180885 RepID=A0A242WNX4_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALLDHKRK +VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BFE2918 +----NHSFVKLEKEYDAKLGIYALDTSTSQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDFVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIENRK +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Class A beta-lactamase n=2 Tax=Enterobacter bugandensis TaxID=881260 RepID=A0A167JWF6_9ENTR +-eKLNHELTILEKNSGGRLGVALINTENNDLT-LYRADERFAMCSTSKVVAVSALLKKSE +SDKTILGKNIALHEAELVTWSPVTEKNITTGMTLGALSAATLQYSDNTAMNSILNYLGGP +SAVTAFARSIGDEKFRQDRTEPELNTAIPGDERDTSTPLAMATTLQKLTLGDALATPQRQ +QLVEWLKGNTTGAASIKAGLPEGWIVGDKTGSGDYGTTNDIAVIWPPEKSPLILVIFFTQ +PLQDAQSRKDILAEATKIVVSPf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC 05977 TaxID=2203208 RepID=A0A429CDN0_9ACTN +--QFHDRLMELEKKFDARLGVYAVDTGGGATV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVEYSRDDLMKHAPVTRRHVATGMTIRQLCDAAIRFSDGTAGNLLLRDLGGP +AELTAFTRSLGDTVTRMDRVEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTTDKRD +FLRDLFQRNTTGAQRIRAGLPSGWTVADKTGTGEYGTLNDIAVVWPPDKAPIVVAIMSSK +ATKDAPYDQALLAEAAKYVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium sp. AA23 TaxID=1854058 RepID=UPI000801ACF2 +---ATKAVEALEARNGGRLGVMVLDIGTNAAI-EYRADELFPMTSTFKFLAAAGVLKAVD +DAKAKLDDRIVYAASDVEQYSPITKDHAGDGMKLEDVCAAAVVWSDNTAGNLLLRLLGGP +QGLTRFARTLGDDVTRLDRTEPTLNTAIPGDKRDTTSPRAALGDARRILLGDALSPASRK +RLEAWLFEDKVGAARIRAGLPATWGIGDKTGSGDNGTTNIVAILWPPDGAPILVAVYYTG +STAPRASREAVHADMARIIVETf +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora haikouensis TaxID=686309 RepID=A0A1C4XQ70_9ACTN +-----AELTALERRFDARLGVYAVDTGTGRTL-AHRADERFAYASTIKALAAGALLAATS +--EAELDRVVRYDRADLVSHSPVTQRHVADGMTLRAVADAAVRHSDNTAANLMFTELGGP +AGLGRALRGIGDTVTNPVRTETSLNEAAPGDLRDTSTPRAMAGSLRAYALGDALSAADRG +VLVDWLRRNTTGATLIRAGVPAGWRVGDKTGAGGYGTRNDIAVLWPPEGAPIVLAVLSRR +DAKDSQPDDALIAEAARVTID-- +>[subseq from] Beta-lactamase n=1 Tax=Cosenzaea myxofaciens ATCC 19692 TaxID=1354337 RepID=A0A198FJY0_9GAMM +--------KITESQLNGRVGYTVLDLTSGNILeNYRAKERFPMMSTFKVLLCAAVLSRVD +NGQEQLDRRIKYNQNDLIEYSPITEQHITDGMTVGELCEATITMSDNTAANLLLTTIGGP +QKLTEFLRKTGDQTSRLDRNEPTLNEALPGDERDTTTPEAMAKTLHELLTGKTLTASSQQ +QLMDWMIADKVAQPLLRSVLPTGWFIADKTGAGKHGSRGIIAVMGPDKNSARIIVIYLTE +NKATITELNKYIAEIGSSLIKNw +>[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. Alg231-02 TaxID=1922223 RepID=UPI000D5508A1 +-----DTVSQLETEVGGRIGVVLRHTGSDWAV-EHRADERFPMASTFKALLCGAVLSSVD +RGKENLGDLVTYKATELVSYSPVTENHVASGMSVGQLCEATVTMSDNSAANLLLKRVDGP +EGLTRFLRGLGDRVTRLDRNEPAMNEAKRGDPRDTTSPSAVLKTLDRLLFEDVLLPSSRA +QLQQWMVDDKVADELIRKHLPKGWRIADKSGAGHNGSRGIIGVIWPETGKPYLAAAYMTG +SDASFKQRNAVIAEIGKAMIE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. GV031 TaxID=2135727 RepID=A0A4R2X085_9RHIZ +--EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD +KGQENLERRVVYNKVQLVAYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLLLESLGGP +KELTNWLRTLGDGSTRLDRIEPDLNDVAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK +TLIEWLVANTTGNERLRTGLPDSWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTG +ATAPAAEVNPVFGEVGRIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A109N1U7_9BACI +-----QNFAQLEEKFDAKLGIFALDTGTNQTV-TYHPDERFAYTSTHKALAVGALLQQKS +--LEDLKQRITYTQEDLVNYNPITEKHVDAGMTLKELSDASLRYSDNTAGNLILKQLGGP +AGFKKALEEMGDDVTSPERIEPALNEVNPGETHDTSTPRALAESLQAFTLGDALPKEKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DEKDAEYNDKLIAEATKEVIQ-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0002796FBE +-qATHKEFSQLEKKFDTRVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALLAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEASYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1BKA4_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSK +DEKEAIYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0G3FFI8_ECOLX +-----VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATWDE---------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TaxID=1931 RepID=A0A3D0QV17_STRSQ +-----REFKDLEREYDARLGIYAIDTGTGHEV-AYNDGERFAYASTFKALAAGAVLQKYS +--LSGLNRVIKYSEDDLVEYSPVTEKHVGTGMSLGELCEAATRHSDNTAANLLFDALGGP +KGLGAALEEMGDDVTRMERYETQLNEWTPGATRDTSTPRALAEDLRAFVLGDALGKGERA +QLTKWMRTNTTGAELIRAGTPEDWVVGDKSGAGSYGTRNDIAVVWPPDSAPIVVAILSNR +SKADADYDNELIAEAASVVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. RIT694 TaxID=2666190 RepID=UPI0012ACD416 +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKEWDVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderiales bacterium 66-5 TaxID=1895728 RepID=A0A1M3BYG9_9BURK +-------WQAIETASQGRLGVAVLDVASGAFS-GNRLDERFPMCSTFKWLAAAQVLQRVD +QGHEQLKRRVRFGKEVLLPWSPVTERHVDDGMTVGDLCQAAVAMSDNAAGNLLLQSLGGP +QGLTQFVREQGDAVTRLDRWEPQLNESTPGDPRDTSSPRAMAGLLQRLVVGQALSPGSRE +QLARWLRQSKTNAQRLGAGLPAQWRVGSKTGTGPHGSTNDVGVYWREGRPPIVVVAFLTE +SAASLAVRETAIAQVAKAVF--- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora aurantiaca TaxID=47850 RepID=A0A1C6SE09_9ACTN +------ELAALERRSGARIGVFALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFERALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD +LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR +DSRDAEPDDALVAQAARVTV--- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000CF3FEB5 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPFMSTGKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLTTTIGGP +KELTAFMHNMGDHVTRYDRYYGELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. TaxID=1486246 RepID=A0A2D9LIJ2_HALSX +--RITAELERIEQTLEARIGFAAHNLATSQRW-EVNADERFAMSSTFKTLACGALLEQVD +EGQLALETEVSFEESDLVTYSPVTEQYAGHRMTLFELCDATMTTSDNTAANLVLQALGGP +EAVTAFARSMDDPVTRLDRFETELNEATPGDERDTTTPNAMLATLEKLVLGDVLSDESRQ +QLEAWMKGNAVADSLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQAPTVVVFYITE +TDASFKERNAAIASLGEVVQ--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 5mfcol3.1 TaxID=1761756 RepID=A0A1I3Z0C1_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHKDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI0011AAAB3E +-tEMKNDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRK +LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVMK-- +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas lionensis TaxID=1144478 RepID=UPI0009F27D9F +--RITAELERIEQTLDARIGFAAHNLATGQRW-EVNADERFAMSSTFKTLACGALLEQVD +EGQLALETEVSFEESDLVTYSPVTEQYAGHRMTLFELCDATMTTSDNTAANLVLQALGGP +EAVTAFARSMDDPVTRLDRFETELNEATPGDERDTTTPNAMLATLEKLVLGDVLSDESRQ +QLEAWMKGNAVADGLFRAAMPFDWVMADRTGAGGYGSRSITAIIWPPEQPPTVVVFYITE +TEASFKERNAAIASLGEVVQ--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001374ACA0 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWIKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8U9T1_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITKKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X9W9_9BACT +-----RQFAELEARTGSQIGVAAIDISTKRGV-DYRANERFLMCSTFKAMAVAAVLQRVD +QKKEKLDRFVTYGEAQLLEYAPVTRAHVKEGMTLEALCEAAIRQSDNTAANLLLNVLGGP +KGFTEFARSLGDEFTRLDRMEPELNMGSAGDERDTTTPAAMAKDLQRLFTSDVLTVESRK +RLEDWMAANETGTRMIRASVPAGWRVGDKTGRSGKGATNDIAILRPPTGEPIFMAIYTNA +PNESSEGREKLVAEVARIALE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001124D12C +-qATHKEFSQLEKKFDARLGVYAIDTSTHQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSNRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPDRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000E5A2886 +--ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD +KGELTLGKRVKIRAADMLEHAPITERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG +ATVHAAARDAALKAVAAAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Labrenzia sp. THAF82 TaxID=2587861 RepID=A0A5P9D4C0_9RHOB +---IERAVKDAQARLSARIGVVVVDRQTGENW-THRAQERFPLNSTFKTFLCAALLHQGE +AGETDPTRRVEIRGADLVSYSPVTETKVGTDMTLLELCEATVTKSDNTAANLVLDDIGGP +DALNRYLRGIGDTVTRLDRREPEMNYGQPGDERDTTTPAAAAATLQKLVLGNALSADAKK +LLQSWLEDNRVGNSTLRAGLPAGWKVADKTGAGGNGSRSNIAVIWPEGRAPVVVAVYITE +TQASFKARNQAIADIGRAIAS-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=A0A1G7UCQ5_9BURK +----AAQLAQLEQSSGGRLGVFALNTATGAQI-GHRADERFPFCSTFKVILIGAILARST +QVAGLMQQRIHYAQSDVVHYSAVTAEHVSEGMTVAELCAAAIQRSDNTAANLLIKLLGGT +NAVTAYARLIGNPVFRLDRLETSLNDAIPGDPRDTATPAAMVRSLQTLTLGAALPLAQRT +QLLDWLRGNQMGAQRIGAALPAGWTRGDKTGTGDYGTANDLGLVWPPSRPPLILGIYHTQ +PQQDAKARDDVIAAAARIVV--- +>[subseq from] Beta-lactamase n=1 Tax=Falsochrobactrum ovis TaxID=1293442 RepID=A0A364JT59_9RHIZ +--ELISKVQEAEKQINARIGLAIRNTGTGETW-RYRADERFPMASTFKLLACAALLAHID +EGKEDGNRRVTINQNDIVTYSPLTENWVGQAVSLETLCDATMRTSDNTAANKVLEAIGGP +QGLTAFLRAQGDIVTRLDRWETELNEAIPGDPRDTTTPDAIVNLSHKLLLEDGLSAHSRK +TLTNWMMSNEVGGPLMRAGLPETWRIGDRTGAGGYGTRGIVAIIWPPEQKPLIAAIYITQ +TDASIEQRNAAIASIARQLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces flavovariabilis TaxID=284031 RepID=UPI0005EBFD2A +----TARLREIEREHTARLGVYARNMRTGRTV-AYRADERFPMASVFKTLAAAAVLRDLD +RDGEFLARRVHYTQEYVTKYSPITEDHVATGMTVGELCDATIRFSDNTAGNLLLEELGGP +TAITRFARSAGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGDALQPRDRA +RLTDWLLRNTTSGEKFRKALPADWLIADKTGGGRYGGNNDVGVTWPPDGPPIVMSVLTTQ +PEEDAPADNPLVARTAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF314EA +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTVLPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVL--- +>[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000D7486DD +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPVVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTHLDRWETALNEALPSDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD +TPASMAERNQHIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Azorhizobium sp. AG788 TaxID=2183897 RepID=UPI001061D295 +--DLAQKIAALEARSGGRLGVAAIDTGSGARF-AHRGGERFPMCSTFKFLLAAAVLAEAD +RGHLKLTDMVPITRADLIAYAPEVEKHVGSGMSLSDLCAAAVIWSDNGAANLLLRQIGGP +AAVTRFLRSAGDPVTRLDRAEPELNVVPEGSDMDTTTPDAVADDMVRLVLGDVLAPASRG +ALKDWLIGCRTGDKRLRAGLPKGWTVGDKTGTGPTGTSNDVAIAWPPGRAPLVIASYLTA +SRLDGRGSDAIHADVARAVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDAFBF6 +--DADVRLAALEKATGGRLGVSVIDVAMNISF-GRRQEERFAMCSTFKMLAAACILARVD +NGEERLDRKIAYSKADLVDYSPMTENHTEDGMTVAELCEAAVTVSDNTAANLLLASMDGP +EGLTRWLRGIDDQVTRLDRIEPELNEAKKDDPRDTTTPHAMLTTMGKLLLDDAMSEKSRD +QLTAWLVGNKTGDKRLRAGLPKGWTVGDKTGTSATGAIGDVAIVWPSPNRPILITAYIAE +ATKPAKELEYIFAEIGKMV---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis subsp. medellin TaxID=79672 RepID=A0A243NIX5_BACTV +----HDSFAKLEKEYNAKLGIYALDIGTNQTV-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPEETRDTSTPEAIAKTLQSFTLGSALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00137663F5 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTNKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus intestinalis TaxID=1963032 RepID=UPI000B437862 +----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNKVIQYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=J8EYN3_BACMY +----NQSFTKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella aerogenes TaxID=548 RepID=UPI0007B38BDC +-eKLNHELTILEKNSGGRLGVALINTENNDLT-LYRADERFAMCSTSKVVAVSALLKKSE +SDKTILGKNIALHEAELVTWSPVTEKNITTGMTLGALSAATLQYSDNTAMNSILNYLGGP +SAVTAFARSIGDEKFRQDRTEPELNTAIPGDERDTSTPLAMATTLQKLTLGDALATPQRQ +QLVEWLKGNTTGAASIKAGLPEGWIVGDKTGSGDYGTTNDIAVIWPPEKSPLILVIFFTQ +PLQDAQSRKDILAEATKIVVSPf +>[subseq from] class A beta-lactamase n=1 Tax=Afifella aestuarii TaxID=1909496 RepID=UPI000FE33685 +---LTRTLSEVEQRLNARLGAYVLDIETGREW-AQRADERFPMCSTFKLLACGAVLAKVD +MGEEDLERRISFEEKNLVTYSPVTKEHVGGEMTLADLCVAAMTQSDNTAGNLILDSLGGP +PAITSFARSIGDQVTRLDRRETELNEATPGDPRDTTSPRAMARDAQTLLVKGSLSDRSRL +YLKRWMCTNKTGDEKLRAGLPGDFLVGDKTGGGGNGTMNDVAVIWPSGRKPIIASIYLTE +SGASFDERNAGFAEIGKAIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A4U2X889_BACMY +----NQSFAKLEKEYDAKLGIYALDTSTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bordetella genomosp. 12 TaxID=463035 RepID=A0A261V9F8_9BORD +--DAQRQLARLEAREGGRLGVHLLDLQSGYTA-GYRADERFALCSTFKVLAVAAVLARVA +RGEDDLSRPMRLSAADLVAYSPVTQQRLNEGMTLGHLCEAALLVGDNTAANLLLSTIGGP +PGVTAYARTLGDTVTRLDRLETALNQAQPGDERDTTTPAAMAGNLRQLVLGEALPEPQRE +RLRDWLLHCRTGQERLRAGLPAGWAFGHRTGAGEHGTCNDIGVAWPPSTGPVVISAYLTE +SPLPPPERERVLADAARILVH-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A366JPI6_BACFI +--NTNQKFKQLEKEFDARLGVYAYDTGTKKTI-AYRSNERFAYASTFKPLAAAILLERKS +--LEEMDEIVTYTSEDLVTYSPVTEKHVKTGMTLRELCEAAIRFSDNTAGNLILEELGGP +DGFEAALKEMGDTVTKPERFETDLNEAEPGDIRDTSTPKALAASLQKVLIGDFLPEEKRN +LLTDWMRGNVTGDPLIRAGVPSGWEVADKSGAAGFGTRNDIAIVWPPNREPIIVTILSSR +DSKDAEYDNALIAKTAEMTIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. EE-W1 TaxID=2662453 RepID=UPI0012FC8D3F +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSEQFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. KBS0711 TaxID=1649647 RepID=A0A0M2WM99_9BURK +--AAQTQLATLEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLENSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Hamiltonella defensa TaxID=138072 RepID=A0A2D3T1Y1_9ENTR +hqATIDKVKESERQLNARVGYVELDLANGQILnTYRPEERFPMMSTFKVLLCGAVLSRVD +AGLEQLDRRIKYRQSDLVKYSPMTKQHLADGMTVAELCSAAITVSDNTAANLLLSTIGGP +KGLTSFLQKTGDQVTRLDRWETELNQALPGDERDTTTPKIMAQTLHNLLTGKILFVKSRQ +QLQTWMVMNKVGGPLLRSVLPANWFIADKTGAGNHGSRGIIAALGADGKPSRIVVIYLTE +TQATMDERNKQIAEIGASLIKNw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF5EE7F +----NHSFVKLEKEYDAKLGIYALDTSTSQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDFVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVKPGDTRDTSTPKALATSLQAYALGDILSIENRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F954_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIEGP +KELTTFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Class A beta-lactamase n=2 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A657UWL1_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSEQFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Cohnella sp. CC-MHH1044 TaxID=2565925 RepID=A0A4V3WES1_9BACL +---IDRDFVQLESKFSAHLGVYAIDTGTKRIV-AYRPDERFAYASTFKALAVGAVLQQNS +--IDELDKMITYTDKDLVNYSPITEKHVHAGMTLRELSEAAICYSDNTAGNLLLKELGGP +NGFRSALMNIGDSVTNPERFETDLNEAIPGDIRDTSTPRALATSLQAFTLGGVLPTDKRT +ILTDWLKGNITGDNLIRAGVPEGWKVGDKTGAGGYGTRNDIAVVWPPNRDPIVIAILSSR +NTQNAAYDDALIAQATKVALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. WMMB235 TaxID=1172030 RepID=UPI0008DA22D5 +------ELAALERRSGARIGVFALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFARALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD +LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR +DSRDAEPDDALVAQAARAAVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD86353 +--EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD +KGQENLERRVVYDKVQLVAYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLLLESLGGP +KELTNWLRTLGDGSTRLDRIEPDLNDVAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK +TLIEWLVANTTGNERLRTGLPDSWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTG +ATAPAAEVNPVFGEVGRIVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. CNY236 TaxID=1169152 RepID=UPI0004268199 +--AASAQLADLERRYDARVGLFAVDTGTGRIL-THRADERFPLLSTFKPLAAAALLQAHP +LDTGYFDEVVRYAESDLLPYSPVTETKVAEGMTVAQLAEAAITRSDNTAGNLLLRELGGP +EGLTAFLRTIGDSTSRLDRWEIELNTAIPGDERDTTTPAALAADYRAVALGDALGAPERD +RLNSWLQANTTGDTRIRAGLPTGWIVGDKTGTGSYGTANDVAIIRPEGGAPIVIAILTRR +SDADAAANNDLLVDVTRVVVDE- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=A0A031GEI8_9BURK +--TAQTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSA +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMNVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPVPQRQ +QLDTWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLIIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora chalcea TaxID=1874 RepID=UPI000CE36DC7 +-----AELAALERRFGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFARALREVGDSVTRPVRTEPDLNAATPGDERDTSTPRALAGSLRAYTLGEALPPADRD +LLLSWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDSAPIVLAVMSSR +DRRDAKPDDTLVAQAARATV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. 22-7 TaxID=2709707 RepID=UPI0013D2F50D +--NTKQKFKKLEKEFDARLGVYAYDTGTKKTI-TYRSNERFAYASTFKPLAAAILLERKS +--LEEMDEVITYTRDDLVTYSPVTEKHVKTGMTLRELCEAAIRFSDNTAGNLMLEELGGP +EGFEAALKEIGDTVTKPERFETDLNEAEPGDIRDTSTPEALAISLQKVLIGDFLPEEKRN +ILTDWMRGNATGDPLIRAGVPSGWEVADKSGAAGFGTRNDIAIVWPPNREPIIMTILSSR +DSKDAEYDNALIAEAAEMTIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0012930798 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS +--IKKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. GV014 TaxID=2135502 RepID=A0A2U0YYF4_9BURK +--SAEAQLAELERSCGGRLGVVGFHTRSGVRV-QHRAHERFPLCSTFKLMLSASVLERSA +QDASLLQRPMCYGKADLIANSPVTEKHVATGMSVAELCAATIQYSDNAAANVLLKLVGGP +AEVTAFARRIGDQAFRLDRTEPELNTSIPGDLRDTTTPAAMSDSVQRLVLGDALGAGQRE +QLKTWLLGNTTSADRFVAGVPAGWKVADKTGAGSYGSNNDVGVLWPPAGEPLVLSVYLTF +AQKDAKTRNDVVAAATRIAV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar toumanoffi TaxID=180862 RepID=A0A243EDF6_BACTU +-----DSFVKLEKEYNAKLGIYALDTGTNQTV-TYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTGKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B8ZE77_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQIV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGARNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces variegatus TaxID=284040 RepID=UPI0004CD94BF +----TARLREIEREHTARLGVYARNMRTGRTV-AYRADERFPMASVFKTLAAAAVLRDLD +RDGEFLARRVHYTQEYVTKYSPITEDHVATGMTVGELCDATIRFSDNTAGNLLLEELGGP +TAITRFARSAGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGDALQPRDRA +RLTDWLLRNTTSGEKFRKALPADWLIADKTGGGRYGGNNDVGVTWPPDGPPIVMSVLTTQ +PEEDAPADNPLVARTAALLA--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2A7GU92_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKCK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000BF25618 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDNRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTVLPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A443T8M1_BACMY +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILKEIGDTVTTSERFEPELNEVYPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000988FBDA +----NKKLVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQVGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFILDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FTKDANYNNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF44784 +----KHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPGDTRDTSTPMALATSLQTYAQSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH +AKEDAKYEDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2H3PF36_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRLETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZHZ0_KLEOX +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAK----------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. sk2.1 TaxID=2478959 RepID=UPI0011E67903 +---FTQQFKQLEREFDARLGVYAIDTGTGREV-THNADERFAHASTFKALAAAAVLRKYS +--LDGLDEVVTYSRDDLVSDSPVTEKHVDTGMTLKALCDATVRYSDNTAGNLLLDRLGGP +RGLQAVLAGLGDDVTRMERYEPQLNEWSPGATADTSTPRALAKDLRAFVLGDVLGENERA +QLAQWLRTNTTGDELIRAGVPGNWVVGDKTGAGGYGTRNDIAVVWRPGAAPIVMAILSNR +GEADAEYDNELVARAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A1I2V431_BACME +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGEPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFE15D5 +----NQSFAKLEKEYDAKLGIYALDTGTNQIV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGARNDVAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas euvesicatoria TaxID=456327 RepID=UPI0004DFBCB3 +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRVD +QGKLTLAQQVRIRASDMLEHALVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP +AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=A0A1C5A935_9ACTN +--AADHEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT +--DAQLDRVVRYSARDLVAHSPVTEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +AGFESKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALQPADRD +VLIGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DKKDATPDDAVIAQAARVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0008696A96 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKTLREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH +DKEDAEYDDKLIADATKVVLN-- +>[subseq from] Class A beta-lactamase n=2 Tax=Comamonadaceae TaxID=80864 RepID=A0A0S9M535_9BURK +--QAESALAALEQGFAGRIGVCALDTADGALL-GQRADERFPMCSSFKALLAAAILARSS +TEPGLLAQSVRYTRGDLLPHSPVTTQHLAQGMRVDALCEATVQTSDNAAANLLLQRIGGP +AGLTAFMRSIGDAQFRLDRWELELNSSLPGDPRDTTTPRAMAESLRKLVVGDALAPAQRE +QLATWLRGTVTGAARIRAGMPAGWVVGNKTGTSGYGSAIDMAVVWPPARAPLVLAVFTTR +HAADAPALDAPIAQAARIAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI00087238CB +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000E212F8C +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATA------------------ +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. TSRI0078 TaxID=1718951 RepID=A0A1Q4WQ84_9ACTN +--ELAREFERLEEEFDARLGVYAVDTGTEEEV-AHRPDERFAYCSTHKALSAGAVLQRNT +--PEEMEEVITYTEDDLVNYAPITEQHVDTGMTLMEVTDAAVRYSDNTAANLLFEELGGP +DGFEEAMEAVGDDVIEVDRVEPGLSEAAPGDIRDTSTPRAMAESLRKFTLGDALPEDRRD +VLTDMLINNVTGDELIRAGVPEGWEVGDKTGSGGYGTRNDIAVLWPPEGDPIVLAVMSSR +DEEDAEYDNALIAEAAGVVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas cassavae TaxID=56450 RepID=UPI0004926437 +---LRAHWAEIERGTGGRLGISLLDSASGWRI-GQRENERFPMCSTFKLVLAAAVLQRVD +EGQLSLAQPVKIRASDMLEHAPITERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGDP +AGVTAFLRSIGDAKTRSDRYEPEMNQFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRR +QLTDWMIDNRTGDNCLRAGLTADWKIGDKTGSNGTDTRNDIAILWRPDRAPLLLTTYLNG +AKVDGSARDAALKDVASAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF7D1ED +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDHVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPENKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] UPI00100527B4 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00100527B4 +----NKKFVQLEKKFDARLGVYAIDIGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRM +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BEFC0AB +----NHSFVKLEKEYDAKLGIYALDTSTSQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDFVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIENRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Mesorhizobium sp. Pch-S TaxID=2082387 RepID=A0A4P6H5I6_9RHIZ +--EAENKLAELERKHPGRFCVTILDLGSGKRI-QHRADERILMCSTFKALLAALVLARVD +KGEARLDERITFTSKDLVAHSPVTKPHADGSMTIAELCDATVTISDNTAANLLLARFGGP +AALTAFCRRIGDDVTRLDRTEPELNHDGPDDQRDTTTAAAMTETLRKLLFTDVLSAASRH +QLAAWLITNKTGDRRVRAGLPGDWLVGDKTGTNGHGNANDIAVIWPPDRAPLIVTVYCEI +PKISSSERDAAIAEIGRIAAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A4U2N188_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDSVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis lurida NRRL 2430 TaxID=1460371 RepID=A0A2P2FL85_9PSEU +--QFHDRLMELEKKFDARLGVYAVDTGGGATV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVDYSRDDLVKHAPVTGRHVATGMTIRQLCDAAIRFSDGTAGNLLLRDLGGP +AELTAFTRSLGDTVTRMDRIEPAITEATPGDLRDTTTPRAFAADYRKIVLGDTLPADKRD +FLRDLFQRNTTGAQRIRAGLPSGWTVADKTGTGEYGTLNDIAVVWPPDKPPLVVAIMSSK +AAKDAPYDQALLAEAAKYVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2C5A827_9BACI +----NHSFVKLEKEYDAKLGIYALDTSTSQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDFVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIENRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Haematospirillum TaxID=2622088 RepID=UPI00143A6F8D +---AVQRLSDLEGTFDGRLGVFAFDTGSGASL-AWRSEERFPVCSTFKAFLAAAILHRST +SDHGLLDRVISYPLEELVSYSPVTQQHVHSGMRVRDMCAAAIQYSDNTAANLLMRILGGP +DAVTTFMRQAGDTDFRLDRWETDLNTAIPGDLRDTSTPVAIARSLDRLLFGDVLSDMHRA +VLQDWLKGNTTGASRIRAGVPEGWMVGDRTGSGSYGTANAIGVLWPPGRKPVIASIYTTQ +HYREAVWRDDIVAQATRIIVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VDM053 TaxID=1053249 RepID=R8P6X1_BACCE +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAIGALLQKTS +--IEDLDQIIKYTSKDFVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodoligotrophos sp. lm1 TaxID=2561934 RepID=UPI0010C97029 +---LSQKLDDIEKRLGGRLGAVVIDTATGRQW-SRRANERFPLNSTFKAFACAATLARVD +AGEEDLTKSITFDAKDLVTYSPVTEKRVGGKMTLFELCDATMSMSDNSAANMVLGSLGGP +QGLTSFMRSIGDDVTRLDRWETELNEATPGDLRDTTTPKAIAASFQNLLVGDVLSPRSRQ +QLEDWLIGNEVSGPMLRAGLPAGWRIGDRTGAGGHGSRSIVAVIWPPRRKPVIAAIYMTE +VQASMQDRNAAFAELGRALVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora tulbaghiae TaxID=479978 RepID=A0A386WJX7_9ACTN +------ELAALERRSGARIGVFAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DAERDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFARALREVGDRVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYALGEALRPADRD +LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMTSR +DSRDAKPDDALVAQAARATV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF85F55 +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPEDKRE +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus albus TaxID=2026189 RepID=UPI0014192192 +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYTSTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGLTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLIEIGDTVTNPERFEPELNEVYPGEIHDTSTPKALATSLQAFALGDILSTEKRN +LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AC4B27 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAVYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces platensis TaxID=58346 RepID=A0A1Y2NG80_STRPT +---SAQAFKDLERKFDARLGVYAINTGTGREI-TYHQDERFAHASTFKALAAGAVLQKYS +--LPGMDKVITYSRDDLVPHSPVSEKHVDTGMTLRALCDAAVRYSDNTAANLLFDSIGGP +KGLDAVLEKLGDHTTRMVRHEPELNDWSPNDTRDTTTPRAFAKDLRSFVLGDTLPRRERA +QLAKWLRTNTTGAKLIKAGMPKTWLVGDKTGAGSYGTRNDIAVVWPPHAAPIVVAILSNR +TQKDAKYDDALIAQAASVVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces libani subsp. rufus TaxID=249582 RepID=A0A640UBS2_9ACTN +---SAQAFKDLERKFDARLGVYAINTGTGREF-TYHQDERFAHASTFKALAAGAVLQKYS +--LPGMDKVITYSRDDLVPHSPVSEKHVDTGMTLRALCDAAVRYSDNTAANLLFDSIGGP +KGLDAVLEKLGDHTTRMVRHEPELNDWSPNDTRDTTTPRAFAKDLRSFVLGDTLPRRERA +QLAKWLRTNTTGAKLIKAGMPKTWLVGDKTGAGSYGTRNDIAVVWPPHAAPIVVAILSNR +TQKDAKYDDALIAQAAAVVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus vallismortis TaxID=72361 RepID=UPI000EF4F472 +----NEKFVQLEKKFDAKLGVYAIDTGTNKTI-SYRPNERFAYASTYKVLAAAAVLKKNA +--IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEIAEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSAAKALATDLKAFTVDNNLTPDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPHRAPIVVAILSNR +FTEDANYDNALIAEAAKVVLNNf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F5P0_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGS +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +LLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2A7HJQ2_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETALNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI09_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWXKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQ--------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Fictibacillus sp. FJAT-27399 TaxID=1729689 RepID=UPI0009E701F1 +--HIHREFADLESKFDARLGVYAIDTGTDRIV-SYRPNERFAYASTYKALAAGALLQHYS +--IDKLDELVKYTSEDIVSYSPVTQLHVDTGMTLREVIEAAVRYSDNTAGNLLLEKLGGP +TGFETALRQIGDNVTQVDRYETDLNSAIPGDKRDTSTPKALVTSLQAFAVSDLLPTEKRT +ILTDWMRGNTTGDALIRAGAPTDWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR +DAQNATYDNNLIAEAAEVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. BL1 TaxID=2478709 RepID=UPI000EF5E229 +-----AELAALERRSGARIGVFAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DAERDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFARALREVGDRVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYALGEALRPADRD +VLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMTSR +DSRDAKPDDALVAQAARATV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces africanus TaxID=231024 RepID=UPI00142DF261 +----TARLRELEREHTARLGVYARNLRTGRTV-AYRADELFPMASVFKTLAAAAVLRDLD +RDGEFLARRVHYTQEYVTKYSPITEDNVATGMTVGELCDATIRFSDNAAGNLLLKELGGP +TAITRFARSVGDAVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGNALEPRDRA +RLTDWLLRNTTSDERFRKGLPADWLVADKTGGGRYGGSNDVGLTWPPDGAPIVLSVLTTQ +PEEDAPADDALVAKTAAVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B6CWH9_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +GKEDAEYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0J7DCB6_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +GKEDAEYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEB4E96 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILNQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sioyaensis TaxID=67364 RepID=A0A4V1NNT6_9ACTN +----HAALRRLERAHRARVGAFAHNTRTGATV-AYRADTRVPLCSVFKTLAVGAVLRDLD +HNGETLARRVHYTAADVVPNSPVTGKHTATGMTIAELCAAALQRSDNTAANLLLRALGGP +TAVTDFARSLGDRTTRLDRWEPELNSAEPGRTTDTTTPAAIARTYARLLLGDALTPADRG +RLTAWMKANETNTERFRAALPKDWALADKTGTGSYGTGNDVGVAWTPDGTPIVLAVLTGT +AQQAAPSDDPLVAGVTRVLAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas citri pv. fuscans TaxID=366649 RepID=A0A2H1SF88_XANCI +--MLRARWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD +QGKLTLARQVKIHASDMLEHAPVTERHVGGSLSIGELCRATMIYSDNPAANLLFPLVGDP +AGVTASLRGIGDAQTRTDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGGPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 01376 TaxID=2203195 RepID=A0A428Y0S5_9PSEU +--QFHDRLMELEKKFDARLGVYALDTEGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVSYSREDLMKHAPVTGQHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +AALTAFTRSLGDTVTRMDRVEPAITEATPGDLRDTTTPRAFAADYREIVLGDALTADKRD +FLRDLLQRNATGADRIRAGLPPGWTVADKTGTGDYGTLNDIAVVWPPAKAPIVLAIMSSK +AAKDAPYDQALLAEAAKYVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF75BDF +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGSP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Hydrogenovibrio sp. JE_KL2 TaxID=2651188 RepID=UPI00128BDDEF +--NFKQQISELESTFGGRLGVAVWDASSGFQL-QYRGNERFALCSTFKFLLAASVLAKVD +AKEESLSRVVTYSTSDLLNYAPITRKNLHNGMTVSQLLAAALQHSDNTAANLLFEPVRGP +QGLTTFMRSIGDRETRVDRIEPHLNTNIPGDERDTTTPNAMLKSMKKILLGHVLSEASKN +QLTQWMLNNTTGANKLRAGIPTYWPIGDKTGSGNNGAMNDIAIMWPDADDPILVAVYYTG +SKEPFETRNHVLEQVGRIISDQf +>[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium amorphae TaxID=71433 RepID=UPI0011866D6C +--EAENKLAELERKHPGRFCVTILDLGSGKRI-QHRADERILMCSTFKALLAALVLARVD +KGEARLDERITFTSKDLVAHSPVTKPHADGPMTIAELCDATVTISDNTAANLLLARFGGP +AALTAFCRRIGDDVTRLDRTEPELNHDGPDDQRDTTTAAAMTETLRKLLFTDVLSAASRH +QLAAWLITNKTGDRRVRAGLPGDWLVGDKTGTNGHGNANDIAVIWPPDRAPLIVTVYCEI +PKISSSERDAVIAEIGRIAAQ-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A101QJT1_STRCK +----HAELAELERRYGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDRA +-GCAPLDRVVHYPPHDLLPNSPRTEENLATGMTVADLCAAAIQYSDNAAGNLLLRELGGP +AGLTRFYRSLGDEVSRLDRWEPELNTAVPGDPRDTTTPEAIAASLERVTLGRALARADRE +RFVGWLKGNTTSSARFRKGLPKEWVVADKTGTGDYATANDIGVAWTTRRTPVVLAVLSGK +STPDAPVDEALIADAAAVVAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Allokutzneria albata TaxID=211114 RepID=UPI0009F17B27 +-----PDFTALEKQFGARLGVFAIDTATGKTV-SHRENDRFAMASTFKAYAVAALLKRHG +--TEVLSKRVHFTQQEIVTYSPVTEKHVGTGMTVGELCGAAITKSDNTAGNQMLKLLGGP +GELTKFAKSIGDGTTRLDRWETELNTAIPGDERDTSTPKALGSAYRDLVVGDVLPPAERE +QLKKWLLTNTTGGERLRAGIPKEWSIGEKTGTGDYASANDVGVAWTEKGTPIAIAVLTTK +DTKDAKADNALLARTAKLIVE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFA0096 +hqATYKDFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGITLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEMIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00033136DA +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKYVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILKEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAVVWPPNREPIIIVILSSK +DEKEATYDNQLIADATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces auratus AGR0001 TaxID=1160718 RepID=J1RNF2_9ACTN +---AHAALRRLERAHRARVGAFAHNTATGATV-AYRADTRVPLCSVFKTLAVGAVLRDLD +HNGETLARRVHYTAADLVANSPVTGKHVATGMTIAELCAAALQRSDNTAANLLLRALGGP +TAVTAFARSLGDRTTRLDRWEPDLNSAEPWRTTDTTTPAAIGHTYARLLLGDALTPPDRN +RLTAWMKANETNTDRFRAALPRDWALADKTGTGSYGTGNDVGVAWTPDGTPIVLAVLTGT +AQQAAPADDPLVAGVTRVLAK-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000BEF1F2D +----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRRYG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +SKLQAVLAELGDDVTRMERWETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAKPERA +RLAQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +TDADADYDNTLIAKATSAAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Bordetella genomosp. 8 TaxID=1416806 RepID=A0A1W6YK10_9BORD +--ACNTEFADLERAHDRRLGLHAVDTASGKEI-AYRAGERFPFCSSFKAVLAAAVLARDA +RQPGVLDRRISYTRHDLAPYSPVTQNHAGDDMRVADLCAATLRYSDNTAANLLLHLIGGP +PALTAFARAAGNASFRLDRYETALNTAIPGDPRDTSTPRDMGVLLRALMLGDALPARAQA +TLADWMLGNRTGDRRIRAATPADWKVADKTGTGDYASASDIGVLWPPGRRPIVLAIYTTA +RDSKAKADEDLIAAASRIALR-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00081B6929 +------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDRRP +--GARLDERISYGTADLVPYSPVTEKHTGQGMTLRELCDAAVRYSDNTAGNLLLRDIGGP +RGLTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVHGDALPAAGRA +LLTDWLVRNTTGDDRIRAGVPRGWKVGDKTGTAEWGRAHDVAVLWPGDGSPLVLSVLTDR +PDRAASGQDELVAEATRRALD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD107 TaxID=1053229 RepID=J8JVH4_BACCE +----NQSFVKLEKKYDAKLGIYALDTGLNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IKDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKKNTTGDNLIRAGVPGEWKVADKTGSGPYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas monteilii TaxID=76759 RepID=UPI000A2F1AF2 +--AVRQRLATLERTHGRTLGLWALETGSGQRL-AYRADQRFAFCSAFKVLLAGAILQRNE +AEPGLLAQHIDYDAATLVTYSPITQDHLETGMRVADLCAAALQYSDNTAANLLLAQVGGP +AGLTAFARRLGDAVFRLDRDEPTLNTALPDDPRDTTTPLAMGMTLERLLVGKALTVPSRH +QLQAWLEGNTTGASRIRAGVPGDWRVGDKTGTGDYGVANDVAIVWPPGRAPWIVVLFTRG +PDPSSPGDSALIAAAMREVAGAw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter sp. SVU/SVIMS10 TaxID=1476169 RepID=W8TNT7_9GAMM +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQAT------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0010BD16F5 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMRLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillaceae TaxID=186817 RepID=A0A1Q8GU40_9BACI +-tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRQDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTAKALVTSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVMK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. K2I17 TaxID=2014743 RepID=A0A246PVG8_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHVDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL6669N2 TaxID=1938807 RepID=A0A3E0C8V3_9BURK +--AIRRRLVEIEAASGGRLGVSIVDTMSGLHA-GLRTDERFPMCSTFKMLVAGAVLARTD +RGEEDLQRRVVFSQSDVVSNSPATSKHTRELMSIAELCKAAITLSDNTAANLLLATFGGP +AGLTAFARSLGDGVTRLDRIEPMLNEGTPGDLRDTTTPNAMLGNLRELLLGERLSSSSRA +QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPVLVTVYLTE +TDGNAARSNAAIADVGALVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora costi TaxID=1530042 RepID=A0A3A9ZZV6_9ACTN +--DLAPEFRRLEAAFDARLGVHAVDTGTGRTV-AYRADERFAYASTFKALAAAALLDRTS +--AAQLDEVVHYTREDLLAHSPVTERHVATGMSLRDLADAAVRYSDNTAGNLILRRLGGP +AGFGESLRGLGDTATDAERYETSLNEGRPGDRRDTTTPRAFATDLRAYAVGDALGREDRD +ILNGWLRGNTTGDGLIRAGTPQGWVVGDKTGSGGYGARNDIAVLWPPDGAPIVLAVMSRR +DAKDAPYDDALIARATRVVV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus bombysepticus str. Wang TaxID=1330043 RepID=A0A023PGL4_9BACI +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRKMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGNKLIRAGVPKEWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH +DKEDAEYDDTLIADATKIVLE-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia farcinica TaxID=37329 RepID=UPI000BF870F0 +--AATAEFAALEQRFGARLGVYAVDTTSGAEV-AYRADERFGMASTFKGLACGALLREHP +LSSGYFDQVVRYSREEVVSYSPVTETRVDTGMTVAELCHATITVSDNTAGNQILKLLGGP +AGFTAFLRSLGDEVSRLDRWETELNEVPPGEERDTTTPAAVAANYRALVLGDVLAEPERA +QLRDWLVANTTGDQRIRAGVPAGWTVGDKTGGGSHGGNNDVAVAWTETGDPIVIALLSHR +TDPAAKADNALLADATRAVVT-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1ZZ55_BACCE +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQIIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRDIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces africanus TaxID=231024 RepID=UPI000A3A999D +----TARLRELEREHTARLGVYARNLRTGRTV-AYRADELFPMASVFKTLAAAAVLRDLD +RDGEFLARRVHYTQEYVTKYSPITEDNVATGMTVGELCDATIRFSDNAAGNLLLKELGGP +TAITRFARSVGDAVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGNALEPRDRA +RLTDWLLRNTTSDERFRKGLPADWLVADKTGGGRYGGSNDVGLTWPPDGAPIVLSVLTTQ +PEEDAPADDALVAKTAAVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas solaris TaxID=2529389 RepID=A0A558R7B6_9SPHN +---LTARLATIEATTGGRLGVAMLDTATGEAA-GYRADERFPMCSTFKLLVAAMTLHRAG +RLPGTLDAIVPYGAADLIAHSPVTARHVATGLTVRALCHATMTESDNAAANLLLARLGGP +AALTRFVRGLGDRVTRLDRIEPVLNEARPGDPRDTTSPAAMLATMHRLLLGPVLSTPGRA +TLTGWLVANRTGDTRLRAGVPTGWTVGDKTGAGENGTTCDIGIFWPPGRAPILMTAYLTG +ATVPTEARNAALAAAARAVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009ABDB92 +-----KKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIHYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTRANRFETDLNSAVPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGNYGTRNDIAIVWPPNRAPIILAILSNR +FTKDAHYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000278B5F5 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRMNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus tequilensis TaxID=227866 RepID=UPI001436FD33 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-SYRPHERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQMGDHVTKANRFETDLNTAIPGDIRDTSTAKALATDLKAFTLDNTLTIDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKAVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000FF8EBE3 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVTHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTRAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYNNTLIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000DEF8B5E +----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIYYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR +FTKDANYNNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=2 Tax=Albimonas pacifica TaxID=1114924 RepID=A0A1I3FTN7_9RHOB +-----DTVRRIEADLGARVGLSIHDTGRGDRW-EHRADERFPMASTFKVLACAALLSRAD +AGAIDPRRTVAIRQSDLLSYAPVTERRVGGEMSLHALCEATMSTSDNTAANMIIDALGGP +PAVARLARGLGDDVTRLDRREPSLNEGAPGDPRDTSTPAAMAATFETLVLGDALSDGSRA +QLVEWLVGNEVGGPLLRAGLPADWRVGDRTGAGGHGTRGIVAVLWPPNRAPLIAVVFITE +TDASMDARNAAIASIGATIAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium grahamii TaxID=1120045 RepID=A0A5Q0CAF9_9RHIZ +-dEIDRRIAALEKQIGGSIGVSVIDTQTNISF-GYRETESFPLCSTFKVLAAGFVLARVD +KGEENLERRITYDTDKLVTYSPETGKHVGGDMSVGDLCHAAITLSDNTAANLLLESFGGP +KELTNWLRTFGDASTRLDRWETDLNEGKKDDPRDTTTPDAMLDTLGNLTLGSVLSEPSQN +TLVEWMVANTTGGARLRSGLPDGWKIGDKTGTGNNGCAADIAIAWPPGHGPLLMTVYVKQ +ASAPVADINPVFAEVGRIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0003308BFF +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH +DKEDAEYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0008180F21 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH +DKEDAEYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1G4KTY8_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH +DKEDAEYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI001244A09C +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH +DKEDAEYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Halotalea alkalilenta TaxID=376489 RepID=A0A172YI92_9GAMM +-------AREIEQRLEARVGLAIYDTGSNQSW-LYKADERFPMASTFKAFACATLLHQVD +AGGRDLDQTVALAEVDLVPYAPVMEKLVGQRVSLGELCAAAMRTSDNLAANKVLDSIGGP +QGVTAFMRSIGDDTTRLDRWEPDLNQATPGDVRDTTSPAAIATSLRELVLGDTLSASSRA +RLTAWLVENEVGGPLLRSGIPQDWRIGDRTGAGGYGSRGVVAVIWPPEREPIVAAIYITG +TNATMDERNAAIAELGEALA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000278AC31 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. 67 TaxID=2035207 RepID=A0A2M8YK42_9BURK +---AQMQLAALEQAAGGRLGVAAWRHGGELRV-AYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMKLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLENSLPAQQRQ +QLDTWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C0D7M6_BACCE +-------FVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IKDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPEHFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKKNTTGDNLIRAGVPGEWKVADKTGSGPYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ESF0_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLERWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIAR--------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0011AA9123 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLNEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FAKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3G4RT90_ECOLX +---------------------ALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASVAKIVTN-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis quinghaiensis TaxID=464995 RepID=UPI00123AA204 +--ELAREFERLEEEFDARLGVYAVDTGTEEEI-AHRPDERFAYCSTHKAFSAGAVLQRNT +--PEEMEEVITYTEDDLLGYAPVTEQHVDTGMTLMELTDAAVRYSDNTAANLLFEELGGP +DGFEEAMEAVGDDVIEADRVEPGLSEAAPGDVRDTSTPRAMAESLRKFTLGDALPEDRRD +VLTDMLVNNVTGDELIRAGVPEGWEVGDKTGSGGYGTRNDIAVLWPPEGEPIVLAVMSSR +DEEDAEYDNALIAEAAEVVVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9LAR9_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEAFPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERN-------------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000BEBEE06 +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPGDIRDTSTPMALATSLQTYALGDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDVKYDDKLIADATKIVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000C1AD850 +hpDTRARLRELEARHGARIGAFAYNLRTKATV-RHRAAERFPLCSVFKTLAAAAVLRDLD +RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLTTK +PARDAAADSPLVAATATVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. H1a TaxID=1397276 RepID=UPI00046A49EF +----NQSFVKLEKEYDAKLGIYALDTGLNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKKN +FLIDLMKKNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomonospora sp. M2 TaxID=2498135 RepID=A0A4P6Q472_9ACTN +-----PELLRLEREFDADLGVYALDTGSGEVV-SFGADERFAYASTHKAFSAGAVLEQTP +--MEGLDRRITYTEEDLLDYAPITEKHVDEGMELRAVIDAAVRYSDNTAANLLFEELGGP +AGLQAALKEIGDDTTHVDRTEPELNEAAPGDIRDTSTPEAMAATLRKYALGDVLPEEKRE +ILVDMLRRNTTGDDLIRAGVPEGWTVGDKSGAAAYGTRNDIAVLWPPEGDPIVMAVMSER +DAEDAEYDDALIAEAAEAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFE4F72 +----SQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALNQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium miluonense TaxID=411945 RepID=A0A1C3UW95_9RHIZ +--DVDKQLAGLEKKTGGRLGVSVLDTETNISL-GHRQEERFPLCSTYKALAAGFVLARVD +QGVEKLDRRVTYGKEVVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESVGGP +AALTSWLRVTGDTETRLDRNEPDVNQAVKDDLRDTTTPDAMLDTIGLLTLGNTLSETSRD +QLINWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAPAKDVEAVFVEVSKIIVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. WP24 TaxID=2604469 RepID=A0A5D0TMW2_9ACTN +-----REFGRLETEFDARLGVFAVDTGTGTTV-GHRADERFAYASTFKALAAAVLLDRTS +--AADLDEVVRYSRSDLVAHSPVTEKHVTTGMRLRDVVDAAVRYSDNTAANLILRRLDGP +DGFQRELRRLGDTTTEADRYETALNEGRPGDRRDTSTPRAFATDLRAYAVDDALSPEDRD +VLNGWLRRNTTGDALIRAGVPAGWTVGDKTGGGGYGTRNDIAVLWPPEGAPIVLAVMSSR +DTRDAPYDDALIARATRIVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Comamonas sp. SCN 65-56 TaxID=1660095 RepID=A0A1D2S5C7_9BURK +---------AIEVAGQGRLGVAVLDIASQALS-GHRLDERFPMCSTFKWLAAAHVLQRVD +LGHERLERRVRFGKEVLLPWSPVTEHHVGDGMTVGELCQAAVTMSDNAAANLLLQSLGGP +QGLTRFAREQGDGVTRLDRWEPQLNASTPGDPRDTSSPRAMAGLLQRCVLGQALSPGSRA +QLVRWLRASQTNAQRLGAGLPASWRVGSKTGTGPHGTTNDVGVYWREGRSPIVVVAFLTQ +SGASLARREAAIAQVAKAVF--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA4-10 TaxID=1053206 RepID=J8DRP5_BACCE +----NHSFVKLEKEYDVKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDLRIKYTNKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKQPIVLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. Root1455 TaxID=1736465 RepID=A0A0Q7TTC6_9CAUL +------GIVALEARGGGRLGVSVLDTADGKTF-AYRGDERFAMCSTFKALVAGLVLRRVD +QGLERLDRRIVYGKSVLLAHSPATEKHVGEGMTVGALCEATVTLSDNAAANVLLYTFGGP +PALTAFLRGLGDKVTRLDGYEPELNVVRPGEIHDTTSPNAMLATLRALTLGSTLSPASRR +QLIAWLVANQTGDARLRGGLPAGWKVGDKTGSWGIGTTNDIAVIWPPGRSPLLITAYLSR +STLGNDGRNAVIAEVARLVT--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces afghaniensis 772 TaxID=1283301 RepID=S4N2B4_9ACTN +----TARLRKLEREHTARLGVYARNLRTGRTV-AYRAGERFPMASVFKTLAAAAVLRDLD +RDGEFLARRIHYTQDYVTKYSPITEDNVATGMTVGELCDATIRFSDNTAGNLLLKELGGP +TAITRFARSIGDGVTRLDRWEPELNSAEPWRTTDTTTPRAIGLSYARLVLGDALEPRDRA +RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNNDVGITWPPDGPPIVMSVLTTQ +PEEDAPADNPLVAEAAALLA--- +>[subseq from] Class A beta-lactamase n=2 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A1A9PW77_9BACI +--ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASIYKALAAGVLLQQNS +--TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPVHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q5MDA2_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDQQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQI----------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000C34A8B9 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGNIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B3TYI2_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNNIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 2_A_57_CT2 TaxID=665959 RepID=E5WQ45_9BACI +--NTKQKFKKLEKEFDARLGVYAYDTGTKKTI-TYRSNERFAYASTFKPLAAAILLQRKS +--LEEMNEIITYTSDDLVTYSPVTEKHVKTGMTLRELCEAAIRFSDNTAGNLILEELGGP +EGFEAALKEMGDTVTKPERFETDLNEAEPGDIRDTSTPEALAASLQKVLIGHFLSEEKRN +ILTEWMRGNVTGDPLIRAGVPSGWEVADKSGAAGFGTRNDIAIVWPPNREPIIMTILSSR +DSKDAEYDNALIAEAAEMAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF5D27F +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNNIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=2 Tax=Nitratireductor indicus TaxID=721133 RepID=K2P082_9RHIZ +--AFDRKFIEVEAWLGGRLGVAIEDVQTGQKW-SYRSAERFPMNSTFKAFACAAILARAD +AGKEDLSRRIVFQKEDLVTWSPVTEKHVGGRMTLRELCAAASTMSDNTAANLLIDALGGP +RGWTDFMRSIGDDVSRLDRKEPDLTEGTPGDPRDTTSPDAFLESLKAAALGNVLSPASRS +QFIDWLVDNRVSGSLLRAGVPKDWKVGDRTGAGGHATRGITAIMWPPKRKPIIATIFVTE +TRRSMEDRDAAIAEIGRF----- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C2UFF0_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKALAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSEQVEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKAVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C0YYH9_BACCE +----KHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH +AKEDAKYEDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=C7S9Q3_ECOLX +------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATM------------------ +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6BA71_9BACT +--DFANRILPIEERAGARIGVAALDTGTGKRL-DYRSEERFPMCSTFKFLAAAAVLKRVD +EGKENLERFIRYSSQDLLEYAPVTKAHLKDGMTLAALCAAAIEQSDNTAGNLLLDVIGGP +SGLTNFARSIGDQITGLDRKEPELNSAIPGDERDTTTPAAMCADLQRLLLADVLFESSRQ +EFEDWLRHNETGALMIRAGVPQTWSVGDKTGRCANGATNDIAILRPAGRAPILIAIYCIG +STGPADDRAAAIAETARAVVE-- +>[subseq from] class A beta-lactamase n=2 Tax=Janthinobacterium sp. KBS0711 TaxID=1649647 RepID=UPI00110F256D +--AAQTQLATLEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLENSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C0AJI9_BACCE +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKTS +--IEDLDQIIKYTSKDLVNYNPITEKFVDAGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRDIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYNDKLIANATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF7050C +--TVNHSFAKLEKEFDAKLGIYALDTDKNQTV-TYQSDERFAYASTHKALAVGVLLKKKS +--MEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLIEIGDTVTNPERFEPELNKVHPGDTHDTSTPKALATSLQAFALRDVLSIEKRN +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLE-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q6ZY61_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIA---------- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella TaxID=570 RepID=Q6ZY72_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIA---------- +>[subseq from] Beta-lactamase (Putative hydrolase) n=1 Tax=Bacillus sp. 349Y TaxID=2653176 RepID=A0A653WPG8_9BACI +-----ETFANIEDKYDARVGIYAIDTGADRTI-DYRSKERFAFTSTYKALAAALVLKQNT +--MEELEEVITYTEDDLVSYSPITEKYVDTGMTLAELSEAAVRTSDNTAGNLLFEELGGP +EQFQQSLREIGDDVTQADRYETALNEFTPGDPRDTSTPAALATSLQGFAVGDLLPDDKRK +ILIDWMKGNATGDTLIRAGAPEGWTVADKSGAGRYGTRNDIAVVWPPDREPIIMVIMTRH +DTEDADYDDALIAEVAEVTLE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CS149 TaxID=2109332 RepID=A0A2P8B697_9ACTN +----TAAFRKLEREFDARLGVYAIDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +EGLDASLEKLGDDVTRMDRGEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora echinofusca TaxID=47858 RepID=A0A1C5G7K6_9ACTN +----DHEFRQLEKKFDARLGVYAIDTGTGRTV-GYRADDRFAYTSTFKALAAAEVLDETT +--DAELDRVVRYSADDLVTYSPITQLHVADGMTLRAIADAAVRYSDNTAGNLLLRQLGGP +RKFEKELREVGDKVTDAARYETALNEARPGDRRDTSTARALAQDLRAYAVGDALEPADRD +VLTGWLRGNTTGDELIRAGVPDGWVVGDKTGAGGYGTRNDIAVIWPPNRAPIVLAVLSSR +DEEDAGYDNALIARATEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Lysobacter antibioticus TaxID=84531 RepID=UPI0007173688 +---WSAQLRVLEKNSGGRLGVGMLDTGSGQHF-DWRGRERFPMCSTFKFLLAAAVLREVE +RGKLDLQKKIPIAKSDLIAYSPVTEPLAGSSASVAQLCEATMTLSDNTAANLLLPLVGNP +AGLTTFLRGIGDPTTRLDRKEPELNSAIPGDPRDTTSPLAMVATMRKLLLQDGLQPASQK +QLTAWLVANRTGDKRLRAGVPKGARVGDKTGTADT-TSNDLAIIWLPERAPILLTCYLTG +STLDGPGRDAIHASVARLVF--- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5YN87_9BACT +--DAADQIAAIEARLGGRIGVAGLDTGSGKRV-DYWAEERFPLCSTFKFLAAAAVLKRVD +EKKDKLDRFVSYDAKDLLEYAPVTKAHLGNGMTLGALCAAAIEQSDNTAGNLLLEAIGGP +AGLTNFARDLGDRMTKLDRKEPELNSAIPGDERDTTTPASMLGDICQLLVGNTLSASSRQ +QFEEWLQANETGAAMIRAGIPTNWIVCDKTGRGANGATNDIAIVHPPDRAPILLTIYCVG +STASTNDRAAVVAEVAKVVAESf +>[subseq from] class A extended-spectrum beta-lactamase FAR-1 n=1 Tax=Nocardia farcinica TaxID=37329 RepID=UPI00085C4340 +--AATAEFAALEQRSGARLGVYAVDTTSGAEV-AYRADERFGMASTFKGLACGALLREHP +LSSGYFDQVVRYSREEVVSYSPVTETRVDTGMTVAELCHATITVSDNTAGNQILKLLGGP +AGFTAFLRSLGDEVSRLDRWETELNEVPPGEERDTTTPAAVAANYRALVLGDVLAEPERA +QLRDWLVANTTGDQRIRAGVPAGWTVGDKTGGGSHGGNNDVAVAWTETGDPIVIALLSHR +TDPAAKADNALLAEATRAVVT-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2V2H7S5_BACTU +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2C5AJR6_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTYEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF049BF +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTYEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=2 Tax=Rhodanobacter TaxID=75309 RepID=I4VTE5_9GAMM +--QATTQFTALERKHGGRLGVSILDTQSGHRI-QHRAGERFLMCSTFKWLAAAAVLARVD +SGKERLDRRVVYGKDVLLSYAPITSKHVGAPLSVADLCAAAVTLSDNTAANLLLASLGGP +TAITAFARSLGDETTRLDRIEPELNLGRPGDIRDTTTPDAMLSDLHRVLLGDRLSLASRG +LLLQWLRECTTGLDALRAGLPKEWTAGDKTGSGSQGETNDVAIIWPPQRKPLLVTAYYAG +SRAEPAERKAVLAAVGHIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI00077A6014 +----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPGDTRDTSTPMALATSLQTYTLSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH +AKEDAKYEDKLIADATKIVLD-- +>[subseq from] Beta-lactamase (Fragment) n=9 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A2L1J0S4_ECOLX +-----VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATM------------------ +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. HH106 TaxID=1537278 RepID=A0A1E7VYP5_9BURK +--AAHTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAAAVLDRSV +SQPGLLEQLVRYEKKELVTYSPITEKHLADGMRVAELCAATLQYSDNSAANFLMKILGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEMRDTASPASMAHSLQQVLLENSLPAPQRQ +QLATWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLLIAVYYTR +EQKNADTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas endophytica TaxID=2033802 RepID=A0A2N7UC14_9GAMM +-------ARQTEARLDARVGLAIYDTGSGASW-LYNADERFPMASTFKVLACGALLARSD +AGYENRNRLVPIVQSDLVTYSPVTEGWLGQEVSLDALCAATMRTSDNTAANKVLEALGGP +DAVTAFLRSIGDEVTRLDRWETELNEATPGDLRDTTTPAAMANSLQRLLLGDALSPSAKA +TLTEWLVGNEVGEPLLRAGIPDDWHIGDRTGAGGHGSRGVVAIVWPPERAPLIAAIYITQ +TEASMEQRNEAIATIGRALAK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8TZ76_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVINYTKDDLVEYSPVTEKHVDSGMTLGEIVEAAVRSSDNTAGNILLNKIGGP +KGYEKALRQMSDRVTMADRFEAELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNKAPIIIAILSSK +DEREDTYDNQLIAEAAKVVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BEDA998 +----NHSFVKLEKEYDAKLGIYALDTSTSQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDFVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDIRDTSTPKALATSLQAYALGDILSIENRK +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00086404A9 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTRENLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571) TaxID=438753 RepID=A8HV65_AZOC5 +--DLAQKIAALEARSGGRLGVAVIDTGTGARF-AHRGGERFPMCSTFKFLLAAAVLAEAD +RGHLKLTDMVPITRADLIAYAPEVEKHVGSGMSLSDLCAAAVIWSDNGAANLLLRQIGGP +AAVTRFLRSAGDPVTRLDRAEPELNVVPEGSDMDTTTPDAVADDMVRLVLGDVLVPASRG +ALKDWLIGCRTGDKRLRAGLPKGWTVGDKTGTGPTGTSNDVAIAWPPGRAPLVIASYLTA +SRLDGRGSDAIHADVARAVT--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000016E6C3 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGIPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSK +DEKEAIYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFE87D1 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAAGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLITDATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000B4B7F49 +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSNERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKNLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIMLAILSNH +EKEDAKYDDKLIADATKIVLD-- +>[subseq from] Class A beta-lactamase n=2 Tax=Agrobacterium TaxID=357 RepID=A0A546YJW3_AGRRH +-eDADKQLADLEKKTGGRLGVSVLDTETNISL-GYREAERFALCSSYKALAAGFVLARVD +QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCNAAITLSDNTAGNLLLDSFGGP +AALTAWLRTTGDTETRLDRKEPDVNQAIKDDPRDTTTPDSMLDTIGLLTLGNTLSETSRD +QLSNWLVANTTGNARLRAGLPKEWKVGDKTGTGDNGSYADVAVIWLPDRGPILVVTYVGE +ATAPAKDIEAVFAEVGKIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces alni TaxID=380248 RepID=A0A1I1Z2B5_9ACTN +--RTEREFGALEKTFDATLGVFAVDTGSGRSV-AHRADERFAYASTCKALLAGAVLDRSG +--AAGMDRLVRYGAADLVSNSPVTERHAGTGMTLRELCDAAIRYSDNTAANVLFRDLGGP +GRLQEALRALGDRVTRCDRTETDLSDAVPGDPRDTSTPRAMATDLRAYVLGGALPADGRA +LLTDWLRRNTTGATTIRAGVPRDWRVGDKTGTGGYGTRNDIAVLWPPTGAPVVLAVFSRR +AAKDAARDDALIARAAEAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium fredii (strain NBRC 101917 / NGR234) TaxID=394 RepID=C3M8I4_SINFN +--DVTKLVAELEKRTGGRLGVAVLDTETNISF-GYRETERFALCSTFKALAAACALARVD +RGEEKLDRRIVFGKDVLLPHSPVTEKHVGGAMTIAELCDAAITISDNAAGNLLLESFGGP +AGLTAWLRSIGDGTTRLDRTEPDLNEASFGDPRDTTTPAAMLETLGKLVFCSALSEASRQ +QLVEWMVANTTGNARLRAGLPKSWRIGDKTGTSSTGAVSDIAFAGPEGRGPILIAVYTGE +AKLPPAELNPIFAEIARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI0009D001DC +--MLRAQWAQIERGTGGRLGICLLDSATGKRV-GQREHERFPMCGTFKFVLAAAVLQQVD +QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPNGAPMLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. 141 TaxID=2056666 RepID=A0A2M9TC78_9GAMM +---ISAELARIEQALDARIGFAAHDLATGQRW-EVNADERFAMSSTFKTLACGALLEQVD +EGRLALDTEVSFDESALVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLILEALGGP +EAITAFARRLDDSVTRLDRFETELNEATPGDERDTTTPNAMLATLETLVLGDVLTPESRQ +QLQDWMKGNAVADGLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQAPTVAVFYLTE +TDASFEARNEAIASLGKVVQ--- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora purpureochromogenes TaxID=47872 RepID=UPI0004C2E3AC +-----AELAALERRFGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--GADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFARALREVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYALGEALPPADRD +LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR +DSRDAEPDDALVVRAARATV--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas cremoricolorata TaxID=157783 RepID=UPI0003F57C85 +--SAASRFEQIERQHGITLGVFALDTGSGRQL-GYRAEQRLPMCSTFKVMLAGAVLQRSQ +AEPQLLARVIRYPASALVVYSLVTERHVEQGMSVAELCAAALQYSDNTAANLLLELLGGP +AELTAFARRVGDPVFRLDRIEPDLNSALPDDPRDTSSAQAMALSLQRLALGDALDHAGRG +QLQTWLKGNTTGAKRIRAGVPVGWTVGDKTGSGDYGVANDVALLWPAGRAPWVLAVLSRS +AEAKAAWRDAALAEATGVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Sporosarcina globispora TaxID=1459 RepID=A0A0M0G6E8_SPOGL +---TDQKFKQLERDFDARLGVYAYDTGSKKTI-AYRSNERFAYASTFKPLAAAILLEKKS +--LEEMDEIITYKSDDLVTYSPVTEKHVKTGMTLRELCEAAIRFSDNTAGNLMLEELGGP +EGFETALKEMGDSVTKPSRFETDLNEAEPGDIRDTSTPKELAASLQKSLMGDLLPEEKQS +ILTDWMRGNATGDPLIRAGVPSGWEVADKSGAGGYGTRNDIAIVWPPNREPIIMAILSSR +DSKDAEYDNALIAEAAEMTIK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A380YDF4_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGIPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSK +DEKEAIYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2C9YQF6_BACTU +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGSATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEF5FB2 +--ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TNKLNEVITYTKDDLVEYSLVTEKHVDTGMTLGEIAEAAVRTSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces oceani TaxID=1075402 RepID=A0A1E7KJ86_9ACTN +---YAKEFKKLERKYDARLGVYVRDTGTGEEL-TYHADQRFAYASTFKALAAGAVLDEYS +--PKEMEKVVHYSEDDLIEHSPITEKHVDTGMSLRALSAAAVRYSDNTAANLLFDALGGP +KGLDAKLAALGDDVTQMNRYEPELNEATPGDPRDTTTPRAFAKDLREYVLGDVLPKDDRA +LLRKWMRTNVTGDALIRAGVPDDWTVADKSGGGGYGTRNNIAIVRPDEGAPLAVSILSSR +DTKDAEYDDALIAEAASVVADQf +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011459054 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHIDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8IWB2_BACCE +----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH +AKEDAKYEDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS075960 TaxID=2034282 RepID=A0A2B4NIJ3_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNS654 TaxID=1506995 RepID=UPI000517A6D8 +------DFEKLEREFDARLGVYAIDTGTGHEV-THNDRDRFAYNSTFKALQAAAVLSTYS +--LDGMDERVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +GGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas sp. NCPPB 1128 TaxID=1775876 RepID=A0A0J6IQW9_9XANT +--TLQQRLADIERRSGGRLGVSLLD-GSGARLgGQRQDERFPLCSTFKFLLAGAVLQRID +RGELSLERRVPVRKADLLGNAPVSERHVGGTLSVAELCRAAMIYSDNTAANLLLPLVGDP +PGVTRFLRALGDTQIQLDRNEPGMNDFVAGDPRDTTTPAAMAATMRALLLGEVLQPVSRQ +RLIDWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG +ATVDSAARDAALKAVAQAVVA-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus bataviensis TaxID=220685 RepID=K6DNC2_9BACI +--QIHREFAELENKYDARLGVYAIDTGTNRKV-SYRPQERFAYASTYKALAAGALLQHYS +--IDQLDELVTYNSEDIVSYSPVTQLHVDTGMTLREVAEAAVRYSDNTAGNLLLEKLGGT +EEFETALRKIGDHKTQVDRYETDLNSAVPGDTRDTSTPKALATSLKAFVVSDLLPTEKRT +ILTDWMRGNATGDALIRAGAPTGWKVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR +DTQNATYDNTLIAEAAKIALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Shigella flexneri TaxID=623 RepID=UPI0012E7D0DE +------------------------TVPSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Pectobacterium versatile TaxID=2488639 RepID=UPI000D61A897 +-pDTLNTVKDAENKLKARVGYTELDLTNGMILeGYRPEERFPMMSTFKVLLCSAVLSRVD +SGKEQLDRRIHFHQSDLVTYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLSTIGGP +QELTIFLRKTGDHVTRLDRWETALNEALLGDERDTTTPKAMAETLHKLLTGKILTVASQQ +QLMDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYLTG +SQATIEERNKQIAEIGTSLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora TaxID=1873 RepID=UPI00083E20CE +-----AELAALERRFGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFARALREVGDSVTRPARTEPDLNAATPGDERDTSTPRALAGSLRAYTLGEALPPADRD +LLLSWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDSAPIVLAVMSSR +GSRDAKPDDTLVAQAARATV--- +>[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora rectivirgula TaxID=28042 RepID=A0A073AY97_9PSEU +---AREEFSRLERDFDARLGVYAVDTATGREV-AYRADERFAHASTFKALAAGELLRRNS +--LEELDRTITYSRDDLVTYSPITEKHVDSGMPLREVIAAAIRHSDNTAGNLLLRELGGP +DGFTAALRRIGDTTTRADRFETDLNETAPGDPRDTSTPRALATSLRAYAVDDVLPADKRA +VLNEMLRTNTTGDALIRASAPAGWQVGDKTGAASHGTRNDIAVVWPPERAPIVLAVLSDR +EAEDADYEDALIARAAAVVFE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FA84_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRILLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium agaricidamnosum TaxID=55508 RepID=A0A3G2E3Y2_9BURK +---AHTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLEQLVRYEKKELVTYSPITEKHLADGMRVAELCAATLQYSDNSAANFLMKILGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEMRDTASPASMAHSLQQVLLENSLPAPQRQ +QLATWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLLIAVYYTR +EQKNADTNQDIITAATRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. HH107 TaxID=1537279 RepID=UPI000873BE4E +---AHTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLEQLVRYEKKELVTYSPITEKHLADGMRVAELCAATLQYSDNSAANFLMKILGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEMRDTASPASMAHSLQQVLLENSLPAPQRQ +QLATWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLLIAVYYTR +EQKNADTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD115 TaxID=1053230 RepID=J8H3A6_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEAVYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A7XMH1_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus subtilis TaxID=1423 RepID=BLAC_BACSU +----NKKFVQLEKKFDARLGVYAIDIGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRM +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A654MTJ3_BACIU +----NKKLVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLNEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDTNYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009947615 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILKEIGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BED7C5B +----RHSFVKLEKEYDAKLGIYALDTDTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPKRFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGAYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0008589B87 +----RHSFVKLEKEYDAKLGIYALDTDTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPKRFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGAYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE0ACEA +--DVDKQLGDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD +QGAEKLDRRVTYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPNVNQAVKDDPRDTTTPDAILDSIGLLTLGNTLSETSRD +QLVNWLVGNTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAPAKDVEAVFAEVSRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. CNZ297 TaxID=2572905 RepID=A0A559VES7_9ACTN +------ELAALERRSGARIGIFALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFERALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD +LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR +DSRDAEPDDALVAQAARATV--- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL17N1 TaxID=1938798 RepID=A0A495G2Y4_9BURK +--AIRRRLVEIEAASGGRLGVSIVDTMSGLHA-GLRTDERFPMCSTFKMLVAGAVLARTD +RGEEDLQRRVVFSQSDVVSNSPATSKHTRELMSIAELCKAAITLSDNTAANLLLATFGGP +AGLTAFARSLGDGVTRLDRIEPMLNEGTPGDLRDTTTPNAMLGNLRELLLGERLSSSSRA +QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPVLVTVYLTE +TDGKAARSNAAIADVGALVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia ribeironis TaxID=1247936 RepID=A0A1N7RL64_9BURK +--AIRRRLAQIEAESGGRLGVSIVDTTSSLHA-GWRADERFPMCSTFKLLAVGAVLTRVD +HGAEDLQRRVVFSLNGIVPNSPATSRHARELMSIAELCKAALTLSDNAAANLLLASFGGP +AALTAFARSLGDGITRLDRIEPTLNEATPGDPRDTTTPNAMLGNLRALVLGEQLSSASRA +QLLGWLADNQTGGARLRAKLPNDWRVGDKTGTGEHGTANDIAILWPPGRGPVLVTVYLTG +TDGDAARSNAAIANVGALVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000DF2E7EF +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQAT------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces qaidamensis TaxID=1783515 RepID=A0A143CCR0_9ACTN +----TARLRDLEREHTARLGVYARNVRTGRTV-AYRADELFPMASVFKTLAAAAVLRDLD +RDGEFLARRIHYTQAYVTKYSPVTKDHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP +TAITRFARSTGDPVTRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGDALEPRDRA +RLTDWLLRNTTSLERFRKGLPADWLLADKTGGGQYGSNNDVGITWPPDGPPIVMSVLTTQ +PEEDAPADNPLVAGAAALLA--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas nasturtii TaxID=1843581 RepID=A0A3E1KNX3_9XANT +---LRARWAEIERGTGGRLGIGLLDSATGWHI-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIHTADMLAHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP +AGLTAFLRGIGDAHTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPEGAPLLLTTYLNG +AKVDAAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus luti TaxID=2026191 RepID=A0A1K0BGJ4_9BACI +-qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNA +--MDKLNEVIKFTKEDLVEYSPVTERHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEQALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNREPIIIAILSSK +DEKEATYDNRLIEEAAEVVVN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02923 TaxID=1718985 RepID=A0A1Q4W413_9ACTN +----HDRLMELEQKYDARLGVYALDTGTGTVI-AHRADERFAFCSTFKGLAAAAVLHHNP +--LSHLDEVITYGKDDLMKHAPVTARHVTTGMTIRQLCDAAVRYSDGTAGNLLLRDIGGP +ARLTAYARELGDTVTRIDRIEPAISEATPGDPRDTTSPRAFGTNYRKMVLGSALPAEKRA +FLRDLLLRNTTGAQRIRAGVPRGWTVADKTGTGDYGTLNDIAIVWPPKAAPLVIAIMSNR +AAQDAAYHQAVIAEAAAHVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0004E29A5D +----NKKFVQLEKKFDARLGVYAIDIGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRM +ILTDWMRGNATGDELIRAGTPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2H3NNM8_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDHFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGIRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Virgibacillus phasianinus TaxID=2017483 RepID=A0A220U7A1_9BACI +--TLKDEFVKLEKEFDARLGVYALDTGTNQTI-TYRSDERFAYTSTHKALAVGALLQQKS +--IADLDERIMYTRDELVNYNPITEKHVDTGMTLKELCEAAIRYSDNTAGNLILEQLGGP +SGFKKSLREIGDDVTNPERVEPKLNEVKPGETHDTSTPKALATSLQAFTIGDALPAKKRS +LLTDWLKESTTGDTLIRSGVPKGWEVGDKSGAGSYGTRNDIAVIWPPKGEPIVLAVLTSR +DKEDADYNDKLIEQATKQVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A7ZK41_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDAKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000F47763D +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEIIHYSKDDLVTYSPITEKHLETGMSLKEILEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKTLATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02959 TaxID=2020330 RepID=A0A2M9M510_9ACTN +------EFKELERKYGARLGVYAVNTGNGREV-AFNADERFAYASTFKAFAAGAVLRKYS +--LSGMDKVIKYSRSDLVDYSPVTEKHVDTGMTLSDLCDAAVRYSDNTAANLLFDALGGP +KGLAAALAETGDTTTKVERREPELNQWSPGATQDTTTPRAWAADLRAFVLGDALGKDERE +QLTQWLRTNTTGDELIRAGVPKGWTVGDKTGGGGYAVRNDIAVVWPPGAAPIVMAIMSNR +GTKDAAYDNKLIAEAASVAT--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 46 TaxID=1777322 RepID=A0A2S6WJB8_9ACTN +----TARLRELEQEHTARLGVYARNMRTGRTV-AYRADERFPMASVFKTLAAAAVLRDLD +RDGEFLARRIHYTQAYVDAHSPVTENHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP +TAITRFARSTGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGDVLEPRDKA +RLTDWLLRNTTSLERFRKGLPADWLLADKTGGGQYGSNNDVGITWPPDGPPIVMSVLTTR +SEEDAPADNPLVARTAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia brasiliensis TaxID=37326 RepID=UPI0014281BF7 +-----DEFADLEKAFDARLGVYAIDTETGRTV-EYRADERFPYTSTFKALAAAAVLEATT +--PADLDHRISYIRADLVRNSPVTEQNVDRGMTLRDLLDAAVRYSDNTAGNLLFDQLGGP +KGLEQKLRGIGDQVTQMDRTEPELNTAVPGDTRDTSTPRALATDLRSYALGNVLPADDRA +LFVEMLRTNTTGGELIRAGAPSDWLVGDKTGGGEHGTRNDIAVVWPPNRAPIVLSVLSTR +LQADATYDNALIARAAKAALTAf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MMG1533 TaxID=1415546 RepID=A0A0M9YSL0_9ACTN +-kSLTARLRRLENRHGARLGVFAHNLSTGRTV-RHRADERFPVCSVFKTLAAAAVLRDLD +RHGEVLARRIHYTAADLVSGSDQTRKHLATGMTIAELADVAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPVTRLDRWEPDLNSAEPWRETDTTSPYAIGRTYGRLVLGDALNRRDRS +LLTHWLLNNTTSDKRFRAGLPTTWTIADKTGSGSYGTTNNVGIAWTDTGAPVVLSVLSTQ +PDQDAAWDDALVARTAALLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF77A25 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTVQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia otitidiscaviarum TaxID=1823 RepID=A0A516NX53_9NOCA +-----DSFAAMESERAARLGVYAVDTGSGRTV-AYREGERFPMASTFKGLACGALLRDHP +LSTGFFDQVIHFSRDELVEYSPMTEQRVDTGMTVAELCEATITLSDNTAGNKVLELLGGP +AGFTAFLRSIGDEVTRLDRWETELNSAVPGDERDTTTPAALAADYRALVLGDVLGEPERA +QLKSWLVANTTGDQRIRAGVPADWTVGDKTGSPAYGGALDVAIAWPPGLAPIVIAVLTTK +SEPDAEPDNALVVDATRAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF5340B +----RHSFVKIEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH +AKEDAKYEDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Agrobacterium rhizogenes TaxID=359 RepID=UPI00055422E1 +--DVDKQLEDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD +QGVEKLDRRVTYGKEVVVTYSPETEKHAGTDMTVAELCGAAIMLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKGDPRDTTTPDAMLDTIGLLTLGNTLSETSRD +QLVYWLIGNTTGNNRLRAGLPKEWKAGDKTGTGDNGSFADIAVIWPPDRGPILVTTFVAE +GTAPAKDIEAVFAEVGKIVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI001066B251 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLETGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIEWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Kribbella antibiotica TaxID=190195 RepID=A0A4R4ZXY3_9ACTN +----NKAFQQLEKQYAARLGVFALDTGSYKTV-SYRANERFAYASTFKSLACGVLLSQAE +----DLDKLIRYTQADLVSYSPITEKHVDTGMTLRELCDAAIRFSDNTAANLILVELGGP +AGLQRALRKLGDGISNVNRNEPTLNEAKPGDKRDTTTPRQLATSLQKFTLGRALPPAKQK +ILNDWLLTNTTGDKTIRAGVPAGWKVGDKTGTAGYGGRNDVAILWPPNRAPIMLAVMSTK +GVKDAPTDDALIAAAAREAVK-- +>[subseq from] Beta-lactamase n=2 Tax=Ensifer TaxID=106591 RepID=W8IFS5_ENSAD +---VDTRLAELEKRTGGRLGVSVLDMETNVSF-GRRESERFAMCSSFKTLAAGFALARAD +QGAEKLDRRIVVAQKDIVAHSPVTEKHVGGEMTIAELCAATLTTSDNAAANLLLENFGGP +PALTAWLRTIGDETTRLDRNEPALNEAKVGDPRDTTTPAAMLETLGNLAFGPVLAEASRK +LLIEWMVANTTGDLRIRAGLPKAWKVGDKTGTNGNGAASDIAIVWPEGRGPLLIAVYIAE +ATAPLAELNTVFADVGRMAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDC7B7A +--DVDKQLGDLEKKIGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD +QGVEKLDRRVTYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAILDSIGLLTLGNTLSETSRD +QLVNWLVGNTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE +ATAPAKDVEAVFAEVSRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Xylophilus ampelinus TaxID=54067 RepID=UPI000B235957 +----AAALARLEDGLNGRLGVFAIDTASGAAL-GHRASERFPICSTFKAILAGAVLARGV +REPGLLDERVRYTKADLIAHSPVTGRELARGMTVAELCAATVQYSDNAAANLLLRRIGGP +EALTAQARAWGDSTFRLDRWETELNSALADDPRDTSTPEAMARLLRTLAVDDGLPTAQRA +RLQDWLRGNTTGGARIRAGMPAAWTVGDKTGTGAHGAASDIAVVWRPQAAPLVLAVYTRL +DAQDAKPRDDVIAAAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora echinospora TaxID=1877 RepID=A0A562DEV8_MICEC +---ADRSFGALEARFAARLGVFAIDTGSGATV-THRADERFAYASTFKALVAAALLDATT +--PAQLDRVVRYTRADLLAHAPVTREHVGTGMSLRDLADAAVRYSDNTAANLILAELGGP +AGLARHLRALGDRTTKPVRTEPALNQATPGDERDTSTPRALATDLRAYVLGDALDAGDRA +LLTDWLRRNTTGDALIRAGVPAGWTVGDKTGTAAYGTRNDIAVLWPPEGTPIVLAVLSSR +AAEDAEHDDALIAEATRVTLD-- +>[subseq from] TEM beta lactamase n=2 Tax=Pectobacterium TaxID=122277 RepID=A0A221T4I2_PECCA +-pDTLNTVKDAENKLKARVGYTELDLTNGMILeGYRPEERFPMMSTFKVLLCSAVLSRVD +SGKEQLDRRIHFHQSDLVTYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLSTIGGP +QELTIFLRKAGDHVTRLDRWETALNEALLGDERDTTTPKAMAETLHKLLTGKILTVASQQ +QLMDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYLTG +SQATIEERNKQIAEIGTSLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02959 TaxID=2020330 RepID=A0A2M9M7D2_9ACTN +----EGELRDLEQRYAARLGVYARNVRTGQVV-AYRAQERFAMCSTFKAVAVAAVLRDQA +-RCAPLDKVIHYPPADILPNSPKTKEHVDTGMAVRDLCAAAIQYSDNAAANLLLRQIGGP +DGLTRFFRSIGDPVSRLDRWETELNTAIPGDPRDTTTPEAIGTSYGQLTLGRALAPADRE +QLVDWLKGNTTSAERFRAGLPHGWIVGDKTGTGDYAAANDIGVAWTTRKTPLVLAVLSSK +DTKDAPVDNALIAEAARILA--- +>[subseq from] Beta-lactamase n=2 Tax=Rhizobiales TaxID=356 RepID=A0A1G5P1M3_AFIMA +-dELMRTLSEVEQRLNARLGAYVLDIETGREW-AQRADERFPMCSTFKLLACGAVLAKVD +MGEEDLERRIIFEEKDLVTYSPVTKEHVGGEMTLADLCVAAMTQSDNTAGNLILDSLGGP +PAITSFARSIGDQVTRLDRRETELNEATPGDPRDTTSPRAMGRDAQTLLVKGSLSDRSRL +YLKRWMCTNKTGDEKLRAGLPGDFLVGDKTGGGGNGTMNDVAVIWPSGRKPIIASIYLTE +SGASFDERNAGFAEIGKAIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00103C8355 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLNEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDTNYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009B55A0F +----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLEKNS +--IEKLNEVIYYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus luti TaxID=2026191 RepID=UPI0009FF3CB6 +-qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNA +--MDKLNEVIKFTKEDLVEYSPVTERHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEQALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNREPIIIAILSSK +DEKEATYDNRLIEEAAEVVVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Labrys sp. WJW TaxID=1737983 RepID=UPI0009EE0E8D +---FAGAIRRIEGEVGGRLGVASLDLKSRVRL-VYRPDELFPLCSTFKLLVAAAVLARVD +QRHERLSRQVPIEAARLLPNSPITARHAGGHLTLAELCEAAITVSDNLAGNLLLEAVDGP +AGLTRYLRSIGDSVSRLDRWEVELNESLPGDPRDTTSPAAMLADLQRLLVGEALSPSSRS +QLTAWLKASRTGDTRLRAGLPAEWAFGDKTGTGERGSTNDVAIAWPPGRTPLLIAAYLTG +TTAAADRRNAALAAVAKAVVEH- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI00114175C3 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKHK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. FJAT-45505 TaxID=2011009 RepID=UPI000C232C27 +---IDEEFAQLEGEFDARLGVYAIDTGKNQIV-EYNPDERFAFASTFKVLAAATLLKQNE +--IKDLEKVVTYSKEDLVTYSPVTEKHVDTGMTLLEISEAAIRKSDNTAGNLLLEALGGP +NKLEQALRDIGDDVTEPERYETELNEFTPGSESDTSTPRAMATNLKKVALDDFLPNEKRE +LLIDWMKGNATGDALIRAGQPEEWVVGDKSGAASYGTRNDIGIVWPPNREPIVIAVMSRH +DTQDAEYDDELVAKAAEITRNAf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0011A4DABE +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDNVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPAEKRE +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI001361FCF0 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIHYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDTNYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A4R6HHR1_BACIU +----IKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAVPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIILAILSNR +FTKDAHYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase FAR-1 n=2 Tax=Nocardia farcinica TaxID=37329 RepID=BLAC_NOCFA +--AATAEFAALEQRFGARLGVYAVDTTSGAVV-AYRADERFGMASTFKGLACGALLREHP +LSSGYFDQVVRYSREEVVSYSPVTETRVDTGMTVAELCHATITVSDNTAGNQILKLLGGP +AGFTAFLRSLGDEVSRLDRWETELNEVPPGEERDTTTPAAVAANYRALVLGDVLAEPERA +QLRDWLVANTTGDQRIRAGVPAGWTVGDKTGGGSHGGNNDVAVAWTETGDPIVIALLSHR +TDPAAKADNALLAEATRAVVT-- +>[subseq from] Beta-lactamase n=4 Tax=Xanthomonas vesicatoria TaxID=56460 RepID=A0A1L5QQS7_9XANT +---LRAQWAEIERGTGGRLGISLLDSATGWRL-GQRENERFPMCSTFKFVLAAAVLQQVD +RGKLSLAQPVKIRASDMLSHAPVTERHVGGALSVGDLCRATMIYSDNPAANLLFPLVGGP +PGVTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLHTLLLGDALQPASRT +QLTDWMIDNRTGDDCLRAGFTRDWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD115 TaxID=1053230 RepID=J8JAA9_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQKITYTHEDLSNYNPITEMHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SAFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKIVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. IHB B 7164 TaxID=1827146 RepID=UPI0007CDA4C3 +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPEDKRA +LLTDWMKRNTTGNALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0006A85C43 +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNC +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL9I2N2 TaxID=1938809 RepID=A0A4R1MLH3_9BURK +--AIRRRLAEIEAASGGRLGVSIVDTMSGLHA-GLRTDERFPMCSTFKVLAAGAVLARTD +RGEEDLQRRVVFSQRDVVSNSPATSKHTSELMSIAELCKAAITLSDNTAANLLLATFGGP +AGLTAFARGLGDGITRLDRNEPTLNEAIPGDPRDTTTPNAMLGNLRELLLGERLCSSSRA +QLLAWLAANETGGARIRAKLPMEWGVGDKTGTGDHGTANDVAILWPPGRGPVLVTVYLTE +TDGDAARSNAAIANVGALVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1C3T9A4_BACMY +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITGKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWSPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A4V2WBQ7_BACTU +----NDSFAKLEKEYNAKLGIYALDTGTNQTV-SYHANDRFAFASTSKSLAAGALLRQNS +--IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIDDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWELADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIAEATKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A5D4PGH2_BACIU +----IKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAVPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIILAILSNR +FTKDAHYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas phaseoli pv. dieffenbachiae TaxID=92828 RepID=A0A1V9GVN6_9XANT +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP +AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTTPAAMAVTLRTLLLGGALQPASRK +QLTAWMIDNRTGDDCLRAGLAADWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora globosa TaxID=47863 RepID=UPI0004C0D9ED +------ELAALERRSGARIGVFALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFARALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD +LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR +DSRDAEPDDALVAQAARATV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces corynorhini TaxID=2282652 RepID=A0A370BI09_9ACTN +-----DAFKGLESKFDARLGVYAVDTGTGEEV-AYNDGERFAYASTFKALAAGAVLREHA +--PDGMDQVVRYSEKDLVSNSPVTEKHVATGMTLAELCDAAVRFSDNTAANLMFDHIGGP +KGLNTVLKELGDDVTRMERREPGLNDWVPGQKRDTSTPRALAEDLRAFVLGDALGAAERA +RLTHWLRTNTTGDELIRAGVPQGWVVGDKTGAGGYGTRNDIAVVWPSAGAPVVMAILTNR +TEKDAEYDNKLIAEAASVIAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD6F0A6 +--EIDRRIGALEKRIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD +KGQENLERRVVYDKAQLVAYSPETEKHVGGEMSVGDLCRAAITLSDNTAGNLLLESLGGP +KELTNWLRTLGDGSTRLDRIEPDLNDVAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK +TLIQWLVANTTGNERLRTGLPETWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTN +ATVATAEINPVFGEVGRIVAE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFC497E +hqATYKDFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPSNRAPIIIAILSSK +DEKEATYDNQLIAEATEMIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodanobacter sp. Root480 TaxID=1736542 RepID=UPI0007010ED9 +--DATAQFTELERKHGGRLGVSILDTQSGRRI-QHRAGERFLMCSTFKWLAAAAVLARVD +SGRERLDRRVVYGKDVLLDYAPVTSKHVGAPLSVAELCAAAVTLSDNTAANLLLASMGGP +TAITAFARSLGDETTRLDRIEPELNLGSPGDIRDTTTPDAMLADLHRVLLGNRLSAGSRD +LLLQWLRGCITGLDAIRAGLPANWTASDKTGSGSQGETNDVAIIWPPRRKPLLVSAYYAG +SHAEPAERKAVLAAVGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobiaceae bacterium TaxID=2072420 RepID=A0A431QJU2_9BRAD +--DLQQTIAGIEADCGGRLGVALLDSASGALS-GHRLDERFPMCSTFKALLAAAILTKVD +AGAEQLSRRIPIAQADILSYAPVTKQHVGTSLSVGELCEATVTLSDNTAANLLLATLDGP +AGLTRTIRGFGDAITRLDRIEPGLNESIPGDPRDTTTPAAMAQTLAKLTVGNTLSAASRD +VLNGWLIGCKTGAAKLRAGLPAEWRVGDKTGAGDHGSSNDVAVIWPAGRGPVIVTSYLTE +TKASDDRRNAAHAAVGRAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00064C7D04 +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQKYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BECDEE6 +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +AEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q5MD99_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAMLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQI----------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF95AEE +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITENHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Labrys neptuniae TaxID=376174 RepID=A0A5C1WBW5_9RHIZ +--DFAAAIGRIEGEVGGRLGVAALDLKSNTRL-AYRPDELFPLCSTFKLLVAAAVLAQVD +QGREQLSRMVSIEAARLLPNSPTTARHAGGQLSLAELCEAAITLSDNLAGNLLLEAVDGP +AGLTRYLRSIGDSVSRLDRWELDLNESLPGDLRDTTSPAAMLADLKVLLVADALSPSSRH +QLNAWLKANRTGGSRLRAGLPDGWEVGDKTGTGERGSTNDVAIAWPPDRPPLLLVAYLTG +TTAPADRRNAALAAVARVVMEH- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BFCC600 +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLEQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPEDKRE +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. HUCO-GS316 TaxID=2692198 RepID=UPI00136A5D50 +---VTARLRALEAQRGARLGVFASNLATGRTV-AHRADERFPVCSLFKTLAAAAVLRDLD +RHGETLARRVHYTADDLVENSPRTEEHLAEGMTIAELADAAIRYSDNTAGNLLLRELGGP +PAITRFARSLGDPVTRLDRWETELNSAEPWRITDTTSPRAIGRTYARLVLGDALNRRDRA +LLTHWLLNNTTSDNRFRAGLPRTWTIADKTGGGFYGTNNDVGIAWTEDGTPLVLAVQTTF +ADEDAPYDHALIAETAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B4382C1 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH +GKEDAEYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar navarrensis TaxID=339658 RepID=A0A243ACT7_BACTU +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKALQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. ok061 TaxID=1761766 RepID=A0A1H6BP99_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPQGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia kururiensis TaxID=984307 RepID=UPI0005AAA98B +--SVRDALAALERTSGGRLGVCAIQTCKPREI-RYRADERFPFCSTFKVVLAAAILARSL +DVPGLMQRRIRYTKHDLAHYSPVSSKHVKDGMTVAELCQAAIQYSDNTAANQLMKVLGGP +QAVTAYAHATGNAAFRLDRWETELNTAIPGDLRDTSTPAAMARTLQTLTVGQALPSAQRD +QLVTWLRGNTTGARRIRAGVPADWQVGDKTGTGDYGTTNDLAILWPPGRAPVMLAVYFTQ +REPKAKARDDVIAAAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A162UZP3_BACIU +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLNEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDEMIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FAKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SS1-1 TaxID=2651869 RepID=UPI0012502DE2 +--DVRARLRELERGHGARLGVFAHNVATGRTV-AHRADERFPVCSLFKPLAVAAVLRDLD +RDGEVLARRIHYTEADLVDNSDVSRAHLETGMTVAELADAAIRFSDNTAGNLLLRQIGGP +TAVTRFARSIGDRVTRLDRWETELNSAEPWRVTDTTSPRAIGRSYARLLLGDALDARDRA +RLTHWMLHNTTSGNRFRAVLPPPWTVADKTGGGSYGANNDAGIAWTESGVPLVLAVMTTR +PEQDAAYDHELIAEATRLVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0013888174 +----DNSFAKLEKEYDAKLGIYALDTGTNQTV-FYRSDDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTISERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKTVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces xinghaiensis TaxID=1038928 RepID=UPI0002D5FA34 +--EVSRRLRALESEHGARLGVFARNLDTGETV-VRRADERFAMCSLFKPVAAAAILRDHD +RRGEFLARRIRYSDTDLVDHSPVTEDHVAQGMTVGELCDAAIRFSDNTAANLLLRELGGP +RAITRFCRSVGDRTTRLDRWETELNSAEPWRVEDTTSPRAIARTYTRLIVGDTLPPADRE +RLTGWMLANTTSGERFRAGLPAGWDLADKTGGGHYGTNNNAGVAWTPDRTPIVLTVLTTK +PDPDAAPDNELIAETAGLL---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8ERS9_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDHFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVL--- +>[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D749B7C +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAVITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARATTTPASMAATLRKLLTSQRLSARSQR +QLLQGMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase CTX-M-27 n=1 Tax=Lysobacter gummosus TaxID=262324 RepID=A0A0S2GBW2_9GAMM +--DWNARLRALEKPTGGRLGVAAIDTGSGQSM-QWRGDERFRMCSSFKYLLAAAVLRQVE +LGKLTLDRKVPITAADMISHAPFTQPLVGSSATVAQLCEATTTLSDNPAANLLLPLVGGP +QGLTRFLRDIGDTVTRCDRTEPELNRGAADDPRDTSSPLAQVATMRALLLGDALKPASRE +QLTAWLVANKTGDKRLRAGLPAGVRVGDKTGTAGE-ANNDVGIVWPPGRAPILIVSYLQT +AKLDDAARDAVHAQVARLVYSAw +>[subseq from] Beta-lactamase (Fragment) n=4 Tax=Enterobacteriaceae TaxID=543 RepID=Q6ZY55_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIA---------- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. LHW51205 TaxID=2248752 RepID=UPI000DE97531 +-----AELAALERRFGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFARALRDVGDRVTRPVRTEPELNAATPGDERDTSTPRALAGSLRAYTLGEALPPADRD +LLLSWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDSAPIVLAVMSSR +GSRDAKPDDTLVAEAARATV--- +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillus vortex V453 TaxID=715225 RepID=A0A2R9T2A0_9BACL +------DFVQLESKFSARLGVYAIDTGTERIV-AYRPDERFAYASTFKALAAGAVLQQNS +--MDTLDKVITYTSKDLVTYSPITEKNVNTGMTLRELSEAAIRYSDNTAGNLLLKELGGP +DGFRTALKQAGDNVTNPERFETDLNEAIPGDNRDTSTPRALATTLQAYTVGDELPTDKRT +LLIDWLKGNTTGDKLIRMAVPEGWEVGDKTGAGGYGTRNDIAVIWPPNKEPTVIAILSSR +DTPDATYDDALIAQAAKVALD-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Pleomorphomonas TaxID=2627136 RepID=UPI00141DFCFF +--KADDDFAKLEKQSGGRLGVAAIDKASGTRI-AYRADERFAMCSTFKFLAAAAVLSRVD +KGELKLDKSIAYGKDDLLSYAPVTKEHVAEGLTLEALCAAAVGVSDNTAANLILKEIGGP +AGWTAYARSLGDATSRLDRTEPELNTAVSGDARDTTTPEAMLGNLDAVMIGDALKEASRD +KLEDWMVSGTVTGPLIRSGVPKTWQVADKSGSGANGTRNDIGVLYRPNTAPILAAIYTTG +SPLDMKGQNKVIADAAALIAARf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus oceanisediminis TaxID=665099 RepID=A0A1S1YIN9_9BACI +--NTKQKFKKLEKEFDARLGVYAYDTGTKKTI-TYRSNERFAYASTFKPLAAAILLQRKS +--LEEMNEIITYTSDDLVTYSPVTEKHVKTGMTLRELCEAAIRFSDNTAGNLILEELGGP +EGFEAALKEMGDTVTKPERFETDLNEAEPGDIRDTSTPEALAASLQKVLIGDFLTEDKRN +ILTEWMRGNVTGDPLIRAGVPSGWEVADKSGAAGFGTRNDIAIVWPPNREPIIMTILSSR +DSKDAEYDNALIAEAAEMAIK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. M21 TaxID=1155617 RepID=A0A2S9XQ52_9BACI +-qATHKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGQ +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN +ILREWMKGNVTGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPSNRAPIIITILSSK +DEKEATYDNQLIAEATEVIVNAf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A0G8CQW8_9BACI +----NQSFAKLEKEYDTKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLHKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI001164741F +--DTRARLRELEARHGARIGAFAYNLRTKATV-HHRAAERFPLCSVFKTLAAAAVLRDLD +RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PAQDAAPDSPLVAAAASVLA--- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q84H50_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQA-------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI00119E01C6 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILKEIGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIILAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011553F07 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTVWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ncost-T6T-1 TaxID=1100828 RepID=A0A1A9CGE5_9ACTN +------AFKKLEREFDARLGVYAIDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus paramycoides TaxID=2026194 RepID=A0A1J9VQ91_9BACI +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNP +--INKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNLLFNKIGGP +KGYEKALRQIGDRVTMAERFETELNEATPGDIRDTSTAKTLATNLKDFTVGNALPADKRK +ILTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR +DEKEATYNNELIAQAAEVVTN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI00048B333E +--DTADAFEKLEAEFDARLGVYAVDTGTGREV-THHADERFAYASTFKALAAGAVLRTYK +--VSGMDRVITYSEDDLVPNSPVTEKHVGTGMTLGALCDAAVRYSDNTAANLLLDQLGGP +KGLGALLAELGDDVTRMERREPELSRWVPGSTRDTTTPRAFAENLRAFALGDVLGDAERA +RLTRWLRTNTTGDEVIRAGVPDNWSVGDKTGSGGYGIRNDIAVLWPPDRAPVVVAVLSNR +DGEDDAYDNRLLAKAAAVVVR-- +>[subseq from] Beta-lactamase n=2 Tax=Paracoccus saliphilus TaxID=405559 RepID=A0A1N7PHH9_9RHOB +----TDRVIEAEQKLQARVGYHMVDLTSGKAT-GYRSDERFPMLSTFKVPLCAAVLARVD +AGEEELDRRIGYASGDLVEYSPVTEQHVGEGMTLSALCDAAITMSDNTAANLLLETIGGP +EGLTTFLRATGDQVSRLDRWETGLNEALPGDPRDTTTPRAMVSTLHRLLFGDALSEAARK +ILITWMENNLVADDLIRVSLPHGWYIADKSGAGARGARAIVGVLGPEDRPERIVAIYMTE +TSASIEARNAEIAKIAKVIVTNw +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces qaidamensis TaxID=1783515 RepID=UPI00099FE57D +----TARLRDLEREHTARLGVYARNVRTGRTV-AYRADELFPMASVFKTLAAAAVLRDLD +RDGEFLARRIHYTQAYVTKYSPVTKDHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP +TAITRFARSTGDPVTRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGDALEPRDRA +RLTDWLLRNTTSLERFRKGLPADWLLADKTGGGQYGSNNDVGITWPPDGPPIVMSVLTTQ +PEEDAPADNPLVAGAAALLA--- +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2Q5_9BACT +------AAQQAETELNARVGLAIHDTGSGTSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTAFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMASSLHELLLGDTLSPAAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLIAAIYLTQ +SDASMEQRNAAIAAIGAALAE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T0Y5_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVNSLHALLLGEALSPAAQT +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSIVAILWPPGQAPLLAAIYLTQ +SDASMEQRNAAIAAIGTALAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Agrobacterium rhizogenes TaxID=359 RepID=UPI000557DFEC +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD +QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCGAAIMLSDNTAGNLLLQSFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDTIGLLTLGNTLSETSRD +QLVYWLIGNTTGNNRLRAGLPKEWKVGDKTGTGNNGSFADIAVVWPPDRGPILVTTFVAE +GTAPAKDIEAVFADVGKIVT--- +>[subseq from] Inhibitor-resistant carbapenem-hydrolyzing class A beta-lactamase KPC-52 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A650DIB9_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARYTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. MYb209 TaxID=1848605 RepID=A0A2S8UQ93_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGFYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF8A5BB +----HNSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF7B20D +----NQSFAKLEKEYDAKLGIYALDTGTNQIV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas sp. Leaf148 TaxID=1736275 RepID=A0A0Q5JBF9_9XANT +---LRAQWAEIERGTGGRLGISLLDSATGWRI-GQRENERFPMCSTFKFVLAAAVLQQVD +RGKLPLAQPVKIGASDMLSHAPVTERHVGSALSVGELCRATMIYSDNPAANLLFPLVGGP +PGVTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAGRDAALKAVAVAV---- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001155642D +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTGTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Uncharacterized protein n=2 Tax=Bordetella genomosp. 9 TaxID=1416803 RepID=A0A261R007_9BORD +----AALFAGLEKAHGRRLGLHAIDTGSGNEI-AYRADERFPFCSSFKAVLAAAVLALDA +RQPGVLDRRISYTTHDLASYSPVTQKHAGGDMRVADLCAATLQYSDNTAANLLLHLIGGP +PALTAFARAAGNASFRLDRYETALNTAIPGDPRDTSTPRDMAVLLGRLVLGDALPAPART +MLADWMLGNKTGDRRIRAATPTGWKVADKTGTGDYASASDIGVIWPPGRQPIVLAIYTTA +RDSKAKADENLIAAAARVALQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia acidivorans TaxID=404580 RepID=UPI000A00D8AB +------AFADLEAKSGGRLGVYAIDTGSGKTV-AYRDGERFPIASTFKGVACGTLLRAHP +LSSGFFDQVIHYPASDLVNYSPETEKHVDSGMTVAELCKAAITLSDNTAGNQILQLLGGP +EGLTAAIRALGDPTTRLDRWETELNTAIPGDERDTTTPAALAADYRALVLGDALAEPERA +QLKSWLLANTTGGKRVRAGVPADWTVADKTGTGDYGAALDAAIVWPPNHAPVVIVVQTAK +PDQHAEGDNAMIAEATKLAVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. Rc5 TaxID=1920666 RepID=A0A1S8XM44_9ACTN +-----AELTALERRFDARLGVYAVDTGTGRTL-AHRADERFAYASTIKALAAGALLAATS +--EAELDRVVRYDRAELVSHSPVTQRHVADGMTLRAVADAAVRHSDNTAANLMFTELGGP +AGLGRALRGIGDTVTNPVRTETSLNEAAPGDLRDTSTPRAMAGSLRAYALGDALSAADRG +VLVDWLRRNTTGATLIRAGVPAGWQVGDKTGAGGYGTRNDIAVLWPPEGAPIVLAVLSRR +DAKDAQPDDALIAEAARVTID-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0007DAF54E +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITKKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH +DKEDAEYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinocorallia populi TaxID=2079200 RepID=UPI000D086F52 +-----TALRRLEKRFGVRLGLWAADTGTGRSL-GHRQDERFAMCSTFKTYAVAAVLKAHS +SDSGLLGRRIRFTRADLVPHSPVTENRVDSGMTVAELCHAALLQSDNTASNELLDLLGGP +SAVTSFARSIGDPVTRLDRREPELNDVTPGSLLDTTTPAGMAAGYRALLLGEALAQAERD +RLTRWMRANRTGQDRIRAGLPRGWTAADKTGTGEYAAANDVGVAWSPDGRPLVLAVFSDK +PAKDGTHEDRVIAEATKIAVR-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces hygroscopicus subsp. limoneus TaxID=264445 RepID=A0A0S2PBU5_STRHL +----HAELAELERRYGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDRA +-GCAPLDRVVHYPPHDLLPNSPRTEENLATGMTVADLCAAAIQYSDNAAGNLLLRELGGP +AGLTRFYRSLGDAVSRLDRWEPELNTAVPGDPRDTTTPEAIAASLERVTLGRALARADRE +RFVGWLKGNTTSSARFRKGLPKEWVVADKTGTGDYATANDIGVAWTTRRTPVVLAVLSGK +STPDAPVDEALIADAAAVVAR-- +>[subseq from] Mutant KPC family beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A6B7HXV1_ENTCL +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPG---DTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000FFE30FA +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEIIHYSKDDLVTYSPITEKHLETGMSLKEILEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKTLATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Methylocella silvestris TaxID=199596 RepID=A0A2J7TKP3_METSI +--QLHGALADLEQKHGGRLGVAILDTATMRRI-ARRGDERFPLCSTFKFLAAAFVLARVD +RKEESLARRIIYASDVLVAHSPITEKHVAGDLPVGEICKAAVSVGDNTAGNLLLDSFGGP +AGLTAYVRSLGDNFTRIDRRETQLNEAAPGDPRDTTTPLAMLEILHKTVLGTALSAPSRQ +QLMAWLVASTTGGNRLRAGIPTGWRVGDKTGSGENNTTNDVAVIWPPRRAALIVTVYYTE +ARASAVERDSVLSEVGRLVA--- +>[subseq from] CTX-M-1-derivative beta-lactamase n=1 Tax=mine drainage metagenome TaxID=410659 RepID=T1B9L8_9ZZZZ +--ALHAQFARIESQTGGRLGVAMLDTHNRIAA-GYRANQRFPVCSTWKLLAVAALLRQVD +EGHENLDRRIRFSASELVVYSPVTKDHVDATMSLRELCDAALVWSDNTAGNLLLAALGGP +SAITRFARAIGDPVTRLDRTEPALNEATPGDARDTTSPRAMLGDLDTLLLGNALTPPSRA +RLNAWLAASQTGARLLRAGFPTNWRVGDKSGAGEHATRNDVAIVTPPGRAPILVAAYLTG +ATVPMPQRDAALAAVARAIHQ-- +>[subseq from] Beta-lactamase n=1 Tax=Gallaecimonas pentaromativorans TaxID=584787 RepID=A0A3N1PGB4_9GAMM +--DFSRTISDIESQYGGRLGVAAFDSRDGRQL-GYREHDTFAMCSTFKALLAAAVLKKAE +QGQLSLDTELSYGKGDLLDYAPVTAAHVDEGMTVSALAGAAITLSDNTAANLLLAKIGGP +AGLTAYIRSLGDNLTRLDRTEPSLNTNLPGDPRDSTTPTAMVALWQKLLLGKALAPASRQ +QLLAWLKATQTGMAKIRAGLPGGWQAGDKTGSCENGGSNDVAIVWPSGQPPYLLAVYYSD +GLGGSAQKNAAIAAVSQAVAEQf +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0011559CBC +-qATHKEFSQLEKKFDAQLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEQHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009B47CB4 +-----KKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAVPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIILAILSNR +FTKDAHYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 13K301 TaxID=2070367 RepID=A0A2N8TQW5_9ACTN +----TARLRDLEREHTARLGVYARNVRTGRTV-TYRADELFPMASVFKTLAAAAVLRDLD +RDGEFLARRVHYTQDYVEKYSPVTEKHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP +TAITRFARSIGDRTTRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGSALAPRDRA +RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNNDVGITWPPDGPPIVMSVLTTQ +PEEDAPADNPLVAGAAALLA--- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q6ZY59_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD +TPASMAERNQHIA---------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mobilis TaxID=2026190 RepID=A0A386V1E6_9BACI +----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDRKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH +AKEDAKYEDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A377W247_KLEPN +-----------------------MDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTLGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI0005947E27 +--MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP +PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAARDAALKAVAAAVR--- +>[subseq from] Beta-lactamase n=1 Tax=Psychrobacter fozii TaxID=198480 RepID=A0A2V4UYP8_9GAMM +--SLVDAVKSAENELGARIGLAVHDLETEQRW-EYRSDERFPLSSTFKTLACANVLHNVD +VGQEKIDRVVRFSKSNLVTYSPVTEKHVGKKMSLGELCQATLSTSDNSAANFILQAIGGP +KYLTQFLRSIGDDTTRLDRWETELNEAIPKDKRDTTTPMAMITTLEKLMLGDTLSTESRQ +QLQSWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPGRKPVIAALYITE +TDASFEDRDAMIAKIGTEIAK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001155637F +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEVAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCFC17 +---ADVRLATLEKATGGRLGVSVLDLAMNISF-GRRQEERFAMCSTFKMLAAACILARVD +NGEERLDRKIAYSKADLVDYSPMTENHTEDGMTVAELCEAAVTVSDNTAANLLLASMDGP +EGLTRWLRGIDDQVTRLDRIEPELNEAKKDDPRDTTTPHAMLTTMGKVLLDDALSEKSRD +QLTAWLVGNKTGDKRLRAGLPKAWTVGDKTGTSATGAIGDVAIVWPSPNRPILVTAYIAE +TTKPAKELEYIFAEIGKMV---- +>[subseq from] Beta-lactamase n=4 Tax=Xanthomonas TaxID=338 RepID=A0A0G8LHR9_9XANT +----GARWAEIERGTGGRLGIGLLDSATGKHF-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP +QGLTAFLRGIGDTQTRSDRHEPEMNQFAAGDPRDTTTPAAMALTLRTLLLGDALQPASRK +QLSDWMIDNRTGDTCLRAGLPRSWKIGDKTGSNGIDTRNDIAILWPPKGAPLLLTTYLNG +ASVDSDARDAALKAVAHAVASY- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SRB_331 TaxID=1969379 RepID=A0A328MGK3_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYETRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00142FD08C +--ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD +KGELTLGKRVKIRAADMLEHASVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP +AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPEAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG +ATVDAAARDAALKAVAAAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0002798A14 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFTSTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001244936B +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-PYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=A0A6C1VV15_BACLI +-tEMKDDFAKLEEQFDAKLGIFALDTGTNQTI-THRPDERFAFASTIKVLTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASIRYSDNAAQNLILKQIGGP +ESLKKELRKLGDEVTNPERYEPELNEVNPGETQDTSTARALATSLQAFALEDQLPSEKRE +LLIDWMKRNTTGDALIRAGVPEDWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAAATKVVIK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A1B1L842_BACTU +------SFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQDLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPEDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKRA---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9AZ20_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNP +--INKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNLLFNKIGGP +KGYEKALRQIGDRVTMAERFETELNEATPGDIRDTSTAKTLATNLKDFTVGNALPADKRK +ILTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR +DEKEATYNNELIAQAAEVVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A2E9BNJ6_9BURK +--DAEARLAALERDCGGRLGVHALDTASGARI-AHRGNELFPMCSTFKLMLAAAILQRGX +QEPALLERRLSYTRAHLXPXSPITEKHLADGMTVAELCAATLQYSDNAAANLLXHQLGGP +AGVTAYARSIGDTVFRLDRWETELNSAIPGDPRDTTSPAAMAASVQRLVLGDALAAPQRS +RLEAWLRGNTTSKERFLAGVPAGWAVGDKTGAGDYGTNNDVGVLWPASGAPLVLAVYLTF +PGKGAKTRNDVVASAVRIVAN-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus cereus group TaxID=86661 RepID=J8LPX4_BACCE +-----HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS +--IEALDERITYTREDLSNYNPITEMHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRKMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE +LLVDWMKRNTTGNKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH +DKEDAEYDDTLIADATKIVLE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A9A424_BACCE +--TTNHSFVNLEKEYDAKLGIYALNTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKNS +--IEDLNQRIKYTSKDLVNYNPITEKYVDSGMTLKELADASIRYSDNTALNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSSPKALATSLQTYALGDILPIEKRD +FLIDLMKRNTTGDNLIRAGVPKEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AEEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2T0DVY3_9BACI +----NQSFAKLEKEYDAKLGIYALDTDTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2S2_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSIVAILWPPGQAPLLAAIYLTQ +SDASMEQRNAAIAAIGTALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. RLB3-6 TaxID=2594457 RepID=A0A515YQF6_9ACTN +--DTRARLRELEARHGARIGAFAYNLRTKATV-RHRAAERFPLCSVFKTLAAAAVLRDLD +RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PAQDAAPDSPLVAAAASVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDFF7E9 +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GYREEERFPLCSTYKALAVGFVLTRVD +QGVEKLDRRVTHGKDVVVTYSPETEKHAGTDMTIAELCGAAITLSDNTAGNLLLQSFGGP +AALTSWLRSTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLINWLVGNTTGDNRLRAGLPKEWKVGDKTGTGNNGCFADIAVVWPPDRGPILVTTFVAE +GTAPAKDIEAVFADVGKIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. CY41 TaxID=2608686 RepID=UPI00135894CF +---ANASVAALEARYGAQVGLFAVDTGTGRTV-THRADERFPFLSTFKTLAAAALLRSRP +LDTGYFDRVVRFHEADLVANSPVTSAAVAEGMTLAQVAEAAITRSDNTAGNLLLREIGGP +EGLTAFLRTLGDPTSRLDRWETELNTAIPGDERDTTTPAALAADYRAAALGDALGASERD +QLVAWLKANTTGDKRIRAGLPANWVTGDKTGTGSYGCANDVAIVWPEGGAPIVIAILSRK +PDADAEANNDLLAEVTKVAVN-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. P44RR-XXIV TaxID=1921145 RepID=A0A4T3FEQ1_9RHIZ +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD +QGVEKLDRRVAYGKDKVVTYSPETEKHAGTDMTIAELCGAAITLSDNTAGNLLLESFGGP +AALTAWLRTTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVGNTTGNNRLRAGLTKEWKVGDKTGTGNNGSYADVAVIWPPERGPILVTTFVAE +GTAPAKDIEAVFAEVGKIVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Agrobacterium sp. B133/95 TaxID=1841656 RepID=UPI000810116B +-eDADKQLADLEKRTGGRLGVSVLDTETNISL-GYREAERFALCSSYKALAAGFVLARVD +QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCNAAVTLSDNTAGNLLLDSFGGP +AALTAWLRTTGDTETRLDRKEPDVNQAIKDDPRDTTTPDSMLDTIGLLTLGNTLSETSRD +QLSNWLVANTTGNARLRAGLPKEWKVGDKTGTGDNGSYADVAVIWLPDRGPILVVTYVGE +ATAPAKDIEAVFAEVGKIVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI16_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGPAESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAK----------------- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00116574DA +--DTRARLRELEARHGARIGAFAYNLRTKATV-RHRAAERFPLCSVFKTLAAAAVLRDLD +RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PAQDAAPDSPLVAAAASVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. Rc5 TaxID=1920666 RepID=UPI00098D4EA2 +-----AELTALERRFDARLGVYAVDTGTGRTL-AHRADERFAYASTIKALAAGALLAATS +--EAELDRVVRYDRAELVSHSPVTQRHVADGMTLRAVADAAVRHSDNTAANLMFTELGGP +AGLGRALRGIGDTVTNPVRTETSLNEAAPGDLRDTSTPRAMAGSLRAYALGDALSAADRG +VLVDWLRRNTTGATLIRAGVPAGWQVGDKTGAGGYGTRNDIAVLWPPEGAPIVLAVLSRR +DAKDAQPDDALIAEAARVTID-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2H0_9BACT +------AAQQVETELDARVGVAIYDTGSGTRW-QYNADEHFPMTSTFKVLACGALLARQD +VGDEDLNRQVPISQSDLVTYSPVTETQVGQEISLDALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLLAAIYLTQ +SDASMEQRNAAIAAIGTALAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium loti TaxID=381 RepID=UPI00047C6C5D +---LTPKIRRLEAKSGGRLGVACRIAGTTAQF-GYRENELFPMCSTFKTLAAALILHRVE +GGIEQLDRSIEVPHNAVVASSPTTKNHAGGEMTVAQLCEAAVTVSDNGAANLLLDSFGGP +AQLTTYLRSIGDTVTRLDRIEPELNESAPDDPRDTTSPLAMIDDCERLALGDSLSQKSRA +QLVDWLVANKTGDDRIRAGLPKGWKCGDKTGTGDRGSTNDAAVIWPTSGNPILMSVYLTG +TKQSLAKRNAVIASVSRALVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix deserti TaxID=2593674 RepID=UPI00131B86B1 +---VAGEFGRLEAEFDARLGVYALDTGSGRTI-EHRADERFAYASTIKALAAGALLARTS +--PAELDRRVTYTSADLVPPSPVAEQHVNEGMTLREVLDAAVRYGDNTAANLMFTQLGGP +QELEKYLRGIGERDTEVDRVEPELNEATPGDERDTSTPRALATVLEKYVLADVLPADDRA +LLTDMLRNNTTGDELIRDGVPDGWVVGDKTGAASYGTRNDIAVLWPPDGDPIVLAVLSSR +DEKDATYDNALIAQAAKAVVT-- +>[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. POLY-S9 TaxID=1576596 RepID=UPI000A4CE130 +-----DTVSQLETEVGGRIGVVLRHTGSDWAV-EHRADERFPMASTFKALLCGAVLSRVD +RGEESLGDLVTYKATELVPYSPVTENHVASGMSVGQLCEATVTMSDNSAANLLLKRVDGP +EGLTRFLRGLGDRVTRLDRNEPAMNEARRGDPRDTTSPSAVLKTLDRLLFEDVLLPSSRA +QLQQWMVDDKVADELIRKHLPKDWRIADKSGAGYNGSRGIIAVLWPETGKPYLAAAYMSG +SDASFKQRNAVIAEIGKAMIE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T3S8_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTAFMRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQT +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLIAAIYLTQ +SDASMEQRNAAIAAIGTALAE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2C5QEE9_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMRDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFILGTALSIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. ROICE36 TaxID=2048670 RepID=A0A2N6ICC3_9BURK +--AAHTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAAALLARSV +SQPGLLDQHVRYEKKDLVAYSPITEKHLADGMNVADLCAAILQYSDNSAANFLMTILGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPATERQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKNADTNQAIITAATRIVT--- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Micromonospora TaxID=2617518 RepID=W7VTP0_9ACTN +-----AELAALERRFGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFARALRDVGDRVTRPVRTEPELNAATPGDERDTSTPRALAGSLRAYTLGEALPPADRD +LLLSWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDSAPIVLAVMSSR +GSRDAKPDDTLVAQAARATV--- +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. Ant5-2-1 TaxID=1755239 RepID=UPI00071826C4 +--AAQTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLENSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKVDTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillus lactis 154 TaxID=743719 RepID=G4HIM8_9BACL +-------FENLENEYDARLGVYAIDTGSGETI-AYRADERFAYTSTFKALASGAVLMQNS +--VEDIDEMISYSAEDLVTYSPITEKHVSTGMTLRDIMDAAIRYSDNTAGNLLLKQLGGP +DGFEAALRQIGDTVIQADRYETELNEAVPGDDRDTSTARALATSLNAFALGDVLPEDKQT +ILTDMLRGNTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDIAIVWPPEGDPIVLAILSSR +DAQDADYDNALIAKAAEAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF04B18 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFGKILREIGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=C8CE60_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNNAERMVVIYLRD +TPASMAERNQ------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. PK3_68 TaxID=2027408 RepID=A0A3A5HQN3_9BACI +--NIDEKLAQLENEFDARIGVYAIDTGTNQTI-EYRPEERFAFASTYKALAAALLLQQNS +--LEELKEVITYTKDDLVPYSPITEKHIDTGMTLLELSEAAVRFSDNTAGNLLFEALGGP +KGFEQALRQIGDNVTQADRFEPDLNTFTPENTRDTSTPKALATSLQAFVIGDLLSGEKRE +QFADLLQGNATGDKLIRAGAPEGWKVGDKSGAGSYGTRNDIAVVWPPDREPIVMAIMSRH +DTKDAKYDDALIAQAAEITL--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SVW1_9BACT +----LDTARQIEARLDARVGLAIYDTGSNTSW-LYRAHERFPMASTFKVLACGALLARRD +AGHTDMEREVSIARSDLVTYSPVTERWVGRGVTLDALCAATMRTSDNTAANKVLEVLGGP +SGLTGFLREIGDDVTRVDRWETDLNEGLPGDARDTSTPAAMAASLRTLLLGDALSSASKE +TLIGWLESNRVGGALLRAGLPDDWRIGDRTGAGGHGTRGVVAIVWPRDRAPLILAVYITQ +TTASMDQRNAAIAAVGRALAQ-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FD47_9BACT +-----------EDQLGARVVYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus muralis TaxID=264697 RepID=UPI000710BC92 +------DFAKLEKKFDAKLGVFALDTGTNETV-TYHPDERFAYTSTHKALAVGVLLQQKS +--IEDLNQRITYTREDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILKQLGGP +TGFKKALEDMGDNVTNPVRIEPDLNEVNPGETHDTSTPRALATSLQAFTLGDTLPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSKR +DKKDAEYNDKLIAETTKEVIK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus bataviensis TaxID=220685 RepID=A0A561D039_9BACI +--HIHREFSELERKFDARLGVYAIDTGTHRIV-SYRANERFAYASTYKALAAGALLQHYS +--IDQLDQLVTYKSEDLVSYSPVTQLHVDTGMTLREVMEAAVRSSDNTAGNLLLEKLGGP +SGFEKALRKIGDNVTQVDRYETDLNTAIPGDRRDTSTPKALATNLQAFTVSDLLPSEKRT +ILTDWMRGNATGDALIRAGAPIGWEVDDKSGAGSYGTRNDIAVVWPPNRDPIVIAVLSSR +ETQNATYDNTLIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Hydrogenovibrio kuenenii TaxID=63658 RepID=UPI0004666BB5 +---FSQQISELEKNYGGKLGVAVWDANTGTQL-HHRGNERFALCSTFKFLLTAAVLAKVD +SKDEKLNRVVTYSKSSLLEYAPVTRKHMQGNMTIAQLAAAAMEYSDNTAANLLFEPARGP +MGLTTFMRSIGDTVTRIDRTEPYLNTNLPNDDRDTTTPNAMLTSMKKILIGNALSPASRN +QLTQWMLNNTTGTNKLRAGIPTHWPIGDKTGSGDNGATSDIAIVWPDADNPILIAVYYTG +SKEPYEIKNHVIEQVGRIVSEQf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces ficellus TaxID=1977088 RepID=UPI0012E80E6F +----TAALEKLEREYGARLGVYAVDTGTGREV-AHRADERFAYASTFKAFAAAAVLREHS +--PGGMDEVITYAEDDLVEHSPVTEKHVRTGMTLRALCDAAVRHSDNTAANLLFDAIGGP +PGLAAALRATGDTVTRVERREPELNQWSPGAESDTTTPRAWAGDLRAFVLGDALGKDERA +QLTRWLRTNTTGDELIRAGVPKGWVVGDKTGGGGYGVRNDIAVVWRPGAAPIVMAIMSNR +GTEDAGYDNALIARAAEVVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. SRB_28 TaxID=1969378 RepID=UPI000DC33D7E +----NQSFAKLEKEYDTKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKDWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011553F37 +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGIRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAT------- +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudorhodoferax sp. Leaf274 TaxID=1736318 RepID=A0A0S9NQZ6_9BURK +--QAELALAALEQGFAGRIGVCALDTADGALL-GQRADERFPMCSSFKAMLAAAILARSS +TEPDLLAQQVRYGRGDLLAHSPVTTLHLDRGMSVAALCEATVQTSDNAAANLLLQRIGGP +AGLTAFMRSIGDDQFRLDRWELALNSSLPGDPRDTTTPRAMATSLRRLAVGDALAPAQRA +QLAAWLRGTTTGAERIRAGMPAGWAVGNKTGTSGYGSAIDVAVVWPPARAPLVLAVFTTR +HAADAPALDAPIAQATRIVAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Arenimonas sp. 3729k TaxID=2608255 RepID=A0A5B2ZD20_9GAMM +--SLRQAWAELEARHGGRLGVAVWDTGSGLRA-SHRGDERFIMCSTFKLVLVGQVLAAVD +AGKESPERRLRWSAEDLVSWSPVTEKHVQDGLTVGELCEATLTTSDNTAANLLLAEHGGP +AGLTAWLRGIGDEVTRLDRFEPGLNVWHEGEPFDTTSLEAMLDTMHKLLLGDVLSPASRQ +RLTDWLIANQTGDNRIRAGLP-GWKVGDKTGSDGKHTSNDVAIAWPPGGAAVLVAVYYTE +SEVNAATRDSVIAEATRAF---- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia otitidiscaviarum TaxID=1823 RepID=A0A379JIY1_9NOCA +-----DSFASMESERAARLGVYAVDTGSGRTV-AYREGERFPMASTFKGLACGALLRDHP +LSTGFFDQVIHFSRDELVEYSPMTEQRVDTGMTVAELCEATITLSDNTAGNKVLELLGGP +AGFTAFLRSIGDEVTRLDRWETELNSAVPGDERDTTTPAALAADYRALVLGDVLGEPERA +QLKSWLVANTTGDQRIRAGVPADWTVGDKTGSPAYGGALDVAIAWPPGLAPIVIAVLTTK +SEPDAEPDNALVVDATRAAV--- +>[subseq from] Beta-lactamase n=1 Tax=Actinopolyspora alba TaxID=673379 RepID=A0A1I1WYS0_9ACTN +----HEDFERLEREFDARLGVYAVDTATGREL-SHRADERFAYASTHKALTAGAVLRQTS +--LEGLDKRITYDRADLVAYSPITKKHVDSGMTLRSVLDAAVRYSDNTAANLMFDELGGP +EGLGAVLREIGDTTTHVDRIEPELNATEPGDIRDTSTPRALATSLRAFTTGDALSKDGRA +VLNRMLRNVTTGDELIRAGTPDGWRVGDKSGAADYGTRNDIAVLWPPERAPIVLAVLSDR +DAADAEYDNALIARAAEVALRSf +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora musae TaxID=1894970 RepID=UPI000EA991FF +-----REFGRLETEFDARLGVFAVDTGTGATI-GHRADERFAYASTFKALAAAVLLDRTS +--AADLDEVVRYSRSDLVAHSPVTEKHVTTGMRLRDVVDAAVRYSDNTAANLILRRLDGP +EGFQRELRRLGDTTTEADRYETALNEGRPGDRRDTSTPRAFATDLRAYAVDDALSPEDRD +VLNGWLRRNTTGDTLIRAGVPAGWMVGDKTGGGGYGTRNDIAVLWPPEGAPIVLAVMSSR +DTRDAPYDDALIARATRIVVD-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2H3NBZ4_9BACI +hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--TEKLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRNSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN +IFTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000863DBE9 +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDLRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKTLREIGDTVTNPEHFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKQN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Pararhizobium polonicum TaxID=1612624 RepID=A0A1C7P419_9RHIZ +-nDIDKQLAALEKRTGGRLGVFVVDTASNASF-GRRQDERFAMCSTFKALAAAFVLARVD +KGAEKLDRRIPVAKTDLLSYSPVVEKQVGKGMTVRELCDAAVTYSDNAAANLLLASFGGP +SRLTAWLRAIGDEATRLDRIEPELNEAKVGDPRDTTTPAAMTRTLGKLLLEGVLSPASRD +QFAAWLVANTTGGKRLRAGLPAGWTVGEKTGTSGHGEAGDIGFMRPRAGHTILASVYIAE +GKKPIRELEPVFAAVGKLIA--- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacteria TaxID=2 RepID=A0A1S7D640_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMD----------------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00040D07EF +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLNEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGNIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas sp. z9 TaxID=2584942 RepID=UPI001142A4C6 +---FEDALDGLERGSGGRLGVCLFDTASGRQW-GRRVDERFPMCSTFKFPLAAAVLRRVE +RGELALDRRVPIRREDLIPHAPVTEKHVGGQLSVGELCQATMIWSDNPAANLLLPLVGGP +AGVTAFLRASGDAVTRNDRDEPEVNRFSPDDPRDTTSPAAMAGSLRRLVLGEVLGAESRR +RLADWLIDNRTGDRRLRAGLPAGWKVGDKTGSNGEDTTNDIAIVWPDGRAPWLLTAYLQG +AKVDADARDGVLRQVGVAAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus oceanisediminis TaxID=665099 RepID=UPI00119D7E60 +--QLHRKFAELENKYDARLGVYAIDTGTNRKV-SYRPQERFAYASTYKALAAGALLHQYS +--IDQLDELVTYNSEDIVSYSPVTQLHIDTGMTLREVTEAAVRYSDNTAGNLLLEKLGGP +KGFETALRKIGDNITQVDRYETELNSAVPGDARDTSTAKALATSLQAFAVSDLIPTEKRT +ILTDWMRGNATGDALIRAGAPTGWEVADKSGAGSYGTRNDIAVVWPPNRAPIVIAVLSSR +ETQNATYDNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus nitratireducens TaxID=2026193 RepID=UPI0008FE5A77 +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAIGALLQKTS +--IEDLDQIIKYTSKDLVNYNPITEKYVDTGMALKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=C8CE59_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGKRGARGIVALLGPNNKAERTVVIYLRD +TPASMAERNQ------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=I7AK71_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVXLCGAVLARVD +AGDEQLERKIHYXXXXLVXYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIA---------- +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=BLAC_PROMI +---VLEAVTNAETELGARIGLAAHDLETGKRW-EHKSNERFPLSSTFKTLACANVLQRVD +LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP +KALTKFLRSIGDDTTRLDRWEPELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ +QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE +TDASFEERNAVIAKIGEQIAK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. BD59S TaxID=2499213 RepID=A0A516QRT3_9BACI +-qATHKEFSQLEKKFDAQLGVYAIDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFRKEDLVDYSPITEKHIDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKVIATNLKDFTVGNALPDDKRK +VLTDWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEIEATYDNQLIAEAAEVVVNTf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF460E7 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPETIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces yunnanensis TaxID=156453 RepID=A0A1M7L284_9ACTN +----AAELRDLERRYAARLGVYARNARTGQVV-AHRAQERFAMCSTFKTVAAAAVLRDHA +-HCAPLDKVIHYPARDILPYSPKTQEHVDTGMTVGDLCAAAIQYSDNAAGNLLLRQLGGP +EGLTRFFRSIGDPTSRLDRWEPDLNTAVPGDLRDTTTPEAIGTSYGRLALGRVLTHDARE +QLVTWLKGNTTSEHRFRAGLPQHWVVGDKTGTGDYASANDVGVAWTGRSTPIVLAVLSTK +SAKDAPVDEALIADAARIVAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0013F433E4 +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHSDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQKYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +AEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase 1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=BLA1_BACMY +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAPEVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFA2F03 +----SQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNELHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAAATKVVLN-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Mesorhizobium TaxID=325217 RepID=A0A434TTM3_9RHIZ +---ATKAVEALEARNGGRLGVMILDIGTNAAI-EYRADELFPITSTFKFLAAAGVLKAVD +DGKAKLDDRIVYAASDVEPYSPVTKEHSGEGMTLEDVCAAAVVWSDNTAGNLLLRVLGGP +QGLTRFARTLGDDVTRLDRTEPTLNTAIPGDKRDTTSPRAALGDARRILLGDALSPASRK +RLEAWLIEDKVGAARIRAGLPATWGIGDKTGSGDNGTTNTVALLWPPNGAPILAAVYYTG +STAPRASREAVHADMARIIVETf +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillus glucanolyticus TaxID=59843 RepID=A0A163IPJ8_9BACL +------DFVQLESKFSARLGVYAIDTGTERIV-AYRPDERFAYASTFKALAAGAVLQQNS +--MDTLDKVITYTSKDLVTYSPITEKNVNTGMTLRELSEAAIRYSDNTAGNLLLKELGGP +DGFRTALKQAGDNVTNPERFETDLNEAIPGDNRDTSTPRALATTLQAYTVGDELPTDKRT +LLIDWLKGNTTGDKLIRMAVPEGWEVGDKTGAGGYGTRNDIAVIWPPNKEPIVIAILSSR +DIPDATYDDALIAQAAKVALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI001191B733 +--AVKGDFAKLEDKFDAKLGIFALDTGTNQTV-TYHPDERFAYTSTHKALAVGALLQQKT +--IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP +TGFKKALEEIGDKVTNPERFEPDLNEVNPGETHDTSTPRALATSLQAFTLRGALPTDKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSMR +DKKDADYNDKLIAEATKEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. WSM2598 TaxID=398261 RepID=UPI00036D2175 +----VARLAALERHDGGRLGVTVRDTGTGRIL-SYRADERFPLCSTFKAVAAAAVLARVD +RGEESLDRRMAYGPGDLDAYAPETRRRVGEGIDLRAACAAAVIWSDNTAANLMLRALGGP +EAVTAFARAQGDAVTRLDRTEPSLNTAIPGDPRDTTSPAAMAALMERILVGPVLSAESRA +LLLGWMTQSPTGAERLRAGLSPGWQVADKTGTGANGTANVVALVRRPGGAPLVASVYLTQ +SPAPAEARNGLHAEVGRLVARTf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=C8CE57_KLEPN +-----DQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQ------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1C4AMF4_BACCE +----NQSFAKLEKEYDAKLGIYALDTDTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C0WW61_BACCE +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLINYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLIEIGDIVTNPERFEPELNEVHPGEIHDTSTPKALATSLQAFALGDILSTEKRN +LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. BA2 TaxID=436595 RepID=UPI001329A657 +-----GDLKALEDKFDARLGVYAIDTGTGREV-AYNAGERFAYNSTFKALAAGAVLGKYS +--LSGLDRKITYSKDDLVANSPVTEKHVDTGMTLGELCDAAVRYSDNAAANLLFDQLGGP +KGLDAALERMGDDVTRMERREPELSTWVPGETRDTSTPRALAKDLRAFVLGDALRKGERA +QLTKWLKTNTTGDKTIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPSDGDPIVMAILSNR +GKKDAEPSDKLIAEATSVAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A0J7EMG5_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0005C64CCB +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQKYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +AEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1C3T490_BACMY +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. UMB0899 TaxID=2029108 RepID=A0A2N6R707_9BACI +---SEHDFSKLEDTFDANLGVYALDTETGHTI-SYHSEERFAFASTSKALAVGVLLQQKS +--IEDLEERITYTREDLVTYSPITEKHVDNGMTLRELSDASLRYSDNTAANLIFKQLGGP +VGFKQALRQLGDDVTNPERIEPDLNDVNPGETHDTSTAKALASSLRTLALEDVLKREKRE +LLLDWMKRNTTGDALIRAGVPEGWEVADKTGAASYGTRNDIAIIWPPNEEPIVLAILSSR +DEKEAAYDDKLIAEATKVVISAf +>[subseq from] Beta-lactamase n=3 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI000219FD72 +-tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFCPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVMK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1S9XX24_BACMY +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudomonas monteilii TaxID=76759 RepID=A0A120HJY5_9PSED +----RQRLATLERTHGRTLGLWALETGSGQRL-AYRADQRFAFCSAFKVLLAGAILQRNE +AEPGLLAQHIDYDAATLVTYSPITQDHLETGMRVADLCAAALQYSDNTAANLLLAQVGGP +AGLTAFARRLGDAVFRLDRDEPTLNTALPDDPRDTTTPLAMGMTLERLLVGKALTVPSRH +QLQAWLEGNTTGASRIRAGVPGDWRVGDKTGTGDYGVANDVAIVWPPGRAPWIVVLFTRG +PDPSSPGDSALIAAAMREVAGAw +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora yangpuensis TaxID=683228 RepID=A0A1C6U248_9ACTN +-----RHFSELERQFGARLGVYAIDTGTGRTV-THRADERFAHASTFKALLAGVLLRRLS +--DADLRRVIRYTEADLLEWAPITSKHVATGMSIEDLIAANVQYSDNTAANLLLEEIGGP +KGLQRELRKIGDRTTNTNRNEPTLNEATPGDPRDTSTPRALATDLRAFALGDVLPAPRRQ +KLIDLLIGNTTGDPYIRAGIPAGWQVGDKTGSGGYGTRNDIAVVWPPTGAPLIIAVLSDR +GVPDAPSADTLIAEATEAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus profundus TaxID=372463 RepID=A0A417YFW8_9BACI +-qTTDNDFAQLEKEFDAKLGVYALDTGSGKII-DYQADERFAYTSTFKPLAAGAVLKQNS +--FEELNETVTYTEDDLVTYSPITEKHVDTGMNLLEISEAAIRYSDNTAGNLLFNELGGP +DGLEKAMREIGDNVINSDRTETNLNEAKPGDVRDTSTPKALATSLQAFALDQLLSESKQD +MLLEWLKTNTTGDTLIRAGVPEDWTVGDKSGAGGYGTRNDIGIVWPPDREPIVIAILSNR +DTEDAEYNDDLIKQATEITVD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A420H426_9BACI +-qATHKEFSQLEKKFDARLGVYAIDTGTHQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--TDKLNEVITYTKDDLVDYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLISEATEVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2C1D4C5_BACCE +----NQSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSGERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRKIGDTVTNPERFEPELNEVQPGENHDTSTPKALATSLRTYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Stappia sp. ARW1T TaxID=2135615 RepID=A0A419Z8P4_9RHOB +--DIEGRLAALENKQGGRLGIAIHDVASGQTF-GNRLNERFLMASTFKLMLAAFVLARVD +REEEQLDRRIPFTKRDLVSWSPGTEKHAGGPLTVAELCEATMTLSDNTAANLLLASFGGP +AALTGFARSLGDETTRHDRTEPALNADGPDDERDTTTPAAMAETLRKLLFGDALSRRSRD +RLTAWMVTNRTGDARLRAGFPADWLVGDKTGTSGKGHANDIGVAWPSGRGALIVTAYCEM +PKAEAKTRDATMAEIARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. UMB0893 TaxID=2066053 RepID=A0A2N5FGS7_9BACI +---VEAGFKNLEKEYEARLGVYALDTGTNKSV-SYRADERFIYASTHKALAVGALLQKKS +--IEDLDERITYTEEDLVNYNPITEKHLDKGMTLKELSDASIRYSDNTAGNLIFEAIGGP +AGFKESLRGIGDKVTEPERIEPDLNNVKPGETRDTSTPKALAESLQAFTLGDALPAEKQN +LLIDWLKRNTTGDALIRAGVPEGWIVGDKTGAGSYGTRNDIAVIWPPKGSPIILAVLSSR +DEADAEYDDELIAKATEEALK-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL27I4N3 TaxID=1938805 RepID=A0A3D9MSH7_9BURK +--AVRRRLVEIEAASGGRLGVSIVDTMSGLHA-GLRTDERFPMCSTFKMLVAGAVLARTD +RGEEDLQRRVVFSQSDVVSNSPATSKHTRELMSIAELCKAAITLSDNTAANLLLATFGGP +TGLTAFARSLGDGVTRLDRIEPMLNEGTPGDLRDTTTPNAMLGNLRELLLGERLSSSSRA +QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPVLVTVYLTE +TDGKAARSNAAIADVGALVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E0F484A +--ELRYKWAEIQRGSGGRLGISLLNSDTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP +PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRQ +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAGRDAALKAVAEAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Rummeliibacillus sp. TYF-LIM-RU47 TaxID=2608406 RepID=UPI00123AFABC +--HTEEAFKQLESEFDARLGVYAIDTKTKKSV-SYQSDERFAFASTYKALAAGAMLKQKS +--MKDLDKIITYTKDDLVTYSPITEKYVDKGMTVKDIATAAIRYSDNTAGNLLFNELGGP +TGFEKALRMMGDKVTQSNRLEPELNLTTPGDLRDTSTPRALASNLQKFVIGDVLPTKKKA +LLTDLLVGNATGDTLIRAGVPKDWVVADKSGAGGYGTRNDIAVVWPPDRKPIVIAILSSR +NTKDATYDDALIAKAAKVVVN-- +>[subseq from] Beta-lactamase n=1 Tax=Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) TaxID=266940 RepID=A6W9C8_KINRD +--DVAAQLARLEREFDARLGVFALDTGTGASV-VHRADERFAYASTFKVLAAAAVLDRTS +--AEELDEVVPFTAEDLVDHSPVTELHVGAGMSLRDLAAAATTVSDNTAANLLLEHLGGP +GGFESALRELGDTVTDPERTETALNEAAPGDVRDTSTPRAMATDLHAYALGDALGEEDRA +VLVGWMRANTTGDALIRAGVPEGWVVGDRTGAGGYGTRNAVAVVWPPAGAPLVLVVMSDR +DAEDADHDDALVAAATAVAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI00051588BB +------DFKKLERAFDARLGVYAIDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +GGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALSAPERA +QLTTWLRTNTTGDAVIRAGVPENWTVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAKPDDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF7F4A5 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP +SKFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus oceanisediminis 2691 TaxID=1196031 RepID=A0A160M853_9BACI +--NTKQKFKKLEKEFDARLGVYAYDTGTKKTI-TYRSNERFAYASTFKPLAAAILLQRKS +--LEEMNEIITYTSDDLVTYSPVTEKHVKTGMTLRELCEAAIRFSDNTAGNLILEELGGP +EGFEAALKEMGDTVTKPERFETDLNEAEPGDIRDTSTPEALAASLQKVLIGHFLTEEKRN +ILTEWMRGNVTGDPLIRAGVPSGWEVADKSGAAGFGTRNDIAIVWPPNREPIIMTILSSR +DSKDAEYDNALIAEAAEMAIK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. jys28 TaxID=2571125 RepID=A0A4U0NJ48_9ACTN +-----PQFAALERKHGARLGVYALATGTGATV-AYRADERFAFCSTFKTLAAAAVLHRNP +--LGHLDKRVTYTEADVNSISPITKDHIATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP +TRLTAYLRGLGDSVSRMDHYEPELNRVRPQDPRDTTTPRAIAADYRKLVLGDALSTDKRA +LLKDWLERNITGAKRIRAGLPKGWTVADKTGTGDYGRANDIAVAWPPHGTPLVLAIMSDR +PGYHTPPKDSLIAETAKQII--- +>[subseq from] Beta-lactamase n=1 Tax=Psychrobacter sp. TaxID=56811 RepID=A0A3D3KIC2_9GAMM +---ILEAVTNAETELGARIGLAVHDLETGKRW-EYKSNERFPLSSTFKTLACANVLQRVD +LGKERMDRVVRFSESNLVTYSPVTEKHVGKKMSLAALCQATLSTSDNSAANFILQAIGGP +KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVMTLEKLLVGETLSIKSRQ +QLVSWLKGNEVGDALFRKGVPNDWIVADRTGAGGYGTRAITAVMWPPNRKSIVAALYITE +TDASFEERNAVIAKIGEQIAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia abscessus TaxID=120957 RepID=UPI0002E8B2CB +--AANASLAEVEARYGAQVGLFAVDTGTGATV-THRADERFPFLSTFKTLAAAALLHAHP +LDTGYFDRVIRFHEADLVEHSPVTGAAVADGMTLAQVAEAAITRSDNTAGNLLLRELGGP +EALTAFLRTLGDPTSRLDRWETELNTAIPGDERDTTTPAALAADYSALVLGDALGARERD +QLITWLRANTTGAERIRAGLPAGWVTGDKTGTGSYGCANDVAVVWPEGGAPIVIAIQSRK +ADVDAEVNNALLAEVTKAVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora musae TaxID=1894970 RepID=A0A3A9YEZ6_9ACTN +-----REFGRLETEFDARLGVFAVDTGTGATI-GHRADERFAYASTFKALAAAVLLDRTS +--AADLDEVVRYSRSDLVAHSPVTEKHVTTGMRLRDVVDAAVRYSDNTAANLILRRLDGP +EGFQRELRRLGDTTTEADRYETALNEGRPGDRRDTSTPRAFATDLRAYAVDDALSPEDRD +VLNGWLRRNTTGDALIRAGVPAGWMVGDKTGGGGYGTRNDIAVLWPPEGAPIVLAVMSSR +DTRDAPYDDALIARATRIVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B5IR39_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1N6TGW1_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTHQTI-SYRHNERFAFASTYKALAAGVLLQQNS +--TDKLNEVITYTKDDLVDYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLISEATEVIVK-- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2C2GFR1_BACTU +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGH +KGYEKALRKMGDWVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A2T5NXB3_9NEIS +----ARQLAELERNAGGRIGVFAQEVDSGRSL-AYRADERFPMCSTFKLLLVGALLQRSA +AQPDLLYRHVSYRREQLIDYSPIAEQYVEQGMSVKDLCDAAMRFSDNTAANLLLEQLGGP +QEVNRFARSLGDGLTRLDRIEPELNRAEPGDPRDTTTPAAMTANLHALLFSPLLPERQRG +LLNDWLLGSTTGNLRIRAGLPAEWRVGDKTGSGGHGAANDVAVAWRPGKSPLLLSVFYWG +SSAMMDERNAVIAAVARVAAAEf +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia lijiangensis TaxID=299618 RepID=UPI0009FCBED1 +-----DRFVALERQYGARLGVFAVNTATGESV-AYRPDERFAMTSTFKGLACAALLHRHP +LATGYFDQIVRYGREELVEYSPVTETRVDSGMTASELCDAAITVSDNTAGNQILKLLGGP +PGLTAFLRSIGDPVSRLDRWETELNTAIPGDERDTTAPERLAANYRAAVLGDVLGEPERA +RLTQWLIANTTGDTRIRAGLPAGWRVGDKTGLGSYGTNNDVAIAWTEAGAPIAIAVMTTK +PDQDAKADNALLADATRIVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia puris TaxID=208602 RepID=A0A366DJ93_9NOCA +-----PEFADLEARHDARLGVFAVDTGSGRSV-AHRADERFPMASTFKGLACGTLLVRHP +LATGYFDQVVRFSADELVEYSPVTETRVDTGMTVAELCHAAITVSDNTAGNQLLKLLGGP +EGFTASLRALGDDTSRLDRWETELNTAIPGDERDTTTPAALVAGYRALVVDDALAEPERA +QLTAWLVANTTGDTRIRAGVPDDWKVGDKTGTPAYGSALDVAVAWPPGRAPIVIAVLSTK +SEQDAEADSALLAEATRAAVH-- +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. Ji-3-8 TaxID=2708539 RepID=UPI0013EE0B8D +----SRSIVALEARSGGRLGVSVLDTANGKTF-AYRGDERFAMCSTFKALVAGLVLKRVD +QGLERLDRRIVYGKNVLLAHSPATEKHVGEGMTVGALCEATVTLSDNAAANVLLYTFGGP +PALTAFLRGLGDKVTRLDGYEPELNVVRPGEIHDTTSPNAMLATLRTLTLGSVLSPASRQ +QLVAWLVGNQTGDRRLRAGLPPGWKVGDKTGSWGDGTTNDIAVIWPPGRSPLLITAYLSR +STLDDDGRNAAIAEVARLVT--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CS057 TaxID=1982764 RepID=A0A209DAA0_9ACTN +----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLREHG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQALLAELGDDVTRMERWETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAGPERA +RLTQWLTANTTGGELIRAGVPKGWTVGDKTGAGRYGTRNDIAVVWPPDAAPLVLAVLSNR +TDADADYDNTLIAKATSAAV--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SVR5_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEMLSPAAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSIVAILWPPGQAPLLAAIYLTQ +SDASMEQRNAAIAAIGTALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=A0A0P6WTD1_9BACI +---TVNKFMQLEKKFDARLGIYAIDTGTNRTV-VYRPDERFAYTSTYKALAAGAVLQQNS +--IGELDEVITYTKDDLVTYSPITEQHVDTGMTLKEIGDAAIRYSDNTAGNLLLQELGGP +NGFENALRQNGDHVTEADRYETDLNSAIPGDIRDTSTARALATSLKAFTVDGILPNGKRT +LLTDWMRGNTTGDELIRAAAPKGWEVGDKSGAGDYGTRNDIAIIWPPNRDPIIIAILSSR +DTKDATYNNELIAKAAKVALSSf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus Rock4-18 TaxID=526988 RepID=A0A2I0R834_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTGTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase class A n=1 Tax=Herbihabitans rhizosphaerae TaxID=1872711 RepID=A0A4Q7L6P5_9PSEU +----HDRLAELEQRFGARVGVFAVATGTGNTV-AHRADERFAFCSTFKALATAAVLHRDP +--MSHLETVVRYTPADLMKSSQITRQHVSTGMTIRQVCDAAVRYSDGTAGNLLFRELGGP +ARLTEFLRSIGDTVTRMDRIEPALTEATPGDPRDTSTPRALGTSYQRLVLGDTLPPDKRA +FLRDLMERNTTGAQRIRAGVPQGWVVADKTGTGDYGTVNDIALVWPPNTPPLLIAIMSSK +PARDATYDQALIAEAARYAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-1813 TaxID=1463888 RepID=UPI0004C55A95 +--RAAKALAQVERRFHARLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAGVVLKRST +--DDELNRVIHYSASDLEEYAPITKRHVGKGMTLRDLVKAALQYSDNTAANLLLDQLGGP +AGLQKALRERGDTTTRVDRTEPTLNEAKPGDTRDTSTPRALGTDLRGFVLGDVLPEGRRQ +LLTSWLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPTSGAPIVVAVLSDR +GSKDAASDDALIKDATKA----- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus halosaccharovorans TaxID=930124 RepID=UPI000994EAE4 +---SQDEFSKLEEKYDAKLGVYALDTGTDVAI-SYRPDERFAYASTSKALAVGVLLQQKS +--IEDLNETITYSRDDLVTYSPITEQHVDTGMTLRDLSDASLRYSDNTAANLIFEQIGGP +EEFKHALRQIGDDMTNPERMEPELNDVAPGETHDTSTAKALAASLQTFALEDALPPEKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAASYGTRNDIAIIWPPNEDPIVLAILSNR +NEKDATYDDELIAEATKVVLSAf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NTK 937 TaxID=1487711 RepID=A0A069K245_9ACTN +--DTADAFEKLEAEFDARLGVYAVDTGTGREV-THHADERFAYASTFKALAAGAVLRTYK +--VSGMDRVITYSEDDLVPNSPVTEKHVGTGMTLGALCDAAVRYSDNTAANLLLDQLGGP +KGLGALLAELGDGVTRMERREPELSRWVPGSTRDTTTPRAFAENLRAFALGDVLGDAERA +RLTRWLRTNTTGDEVIRAGVPDNWTVGDKTGSGGYGIRNDIAVLWPPDRAPVVVAVLSNR +DGEDDAYDNRLLAKAAAVVVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFD5B78 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGSLLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces peucetius subsp. caesius ATCC 27952 TaxID=316280 RepID=A0A2D3UGV6_STRC0 +---FAHELRALEGKYDARLGVYAVDTGSGREV-AYNDGERFAYASTFKALAAGAVLRKYS +--TNGMDRVVTYSADDLIAHSPVTAKHVGTGMSLRDLCEAAVRYSDNTAANLLFDALGGP +GGLDAVLEAMGDDVTRMERREPELSRWAPGETRDTTTPRAFAKDLRAFVLGDALGRNERA +QLTKWLRTNTTGNELVRAGVPKGWVVGDKTGTGGYGARNDIAVVWPPDSAPIVMAIMSNR +GDKDADHDNKLIAEAAGVVA--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas hortorum pv. carotae str. M081 TaxID=863365 RepID=V7Z9E4_9XANT +---LRARWAEIERGTGDRLGIGLLDSATGKHF-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP +QGLTAFLRGIGDAQTRSDRHEPEMNRFAQDDPRDTTTPAAMALTLRTLLLGDALQPTSRK +QLTDWMIDNRTGDTCLRAGLPRSWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +ASVDSDARDAALKAVAQAVASY- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar argentinensis TaxID=180880 RepID=A0A243KNY1_BACTU +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-TYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFGKILREIGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E1F5426 +--MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQQVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP +PGLTRFLRGIGDTKTRSDRIEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAGRDAALKAVAEAVR--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB01883 TaxID=1703943 RepID=A0A1Q5KS96_9ACTN +----EAELRDLEQRYDARLGVLARNVRTGRTL-SHRAGERFAMCSTFKAFAAAAVLRDHG +-DRAPLDRVIPYPPHDILPHSPRTQENLATGMTVGDLCAAAVQYSDNAAGNLLLREIGGP +AGLTRFLRSLGDDVSRLDRWEPELNTAIPGDLRDTTTPRAIGAGLERLALGRALGDADRE +RLVGWLKGNTTGAERFRRGLPDGWVLADKTGTGSYATANDIGVAWTTGRTPVVLAVLSAR +STEDATVDEALVAEAARVIAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora yangpuensis TaxID=683228 RepID=UPI000B84D51B +-----RHFSELERQFGARLGVYAIDTGTGRTV-THRADERFAHASTFKALLAGVLLRRLS +--DADLRRVIRYTEADLLEWAPITSKHVATGMSIEDLIAANVQYSDNTAANLLLEEIGGP +KGLQRELRKIGDRTTNTNRNEPTLNEATPGDPRDTSTPRALATDLRAFALGDVLPAPRRQ +KLIDLLIGNTTGDPYIRAGIPAGWQVGDKTGSGGYGTRNDIAVVWPPTGAPLIIAVLSDR +GVPDAPSADTLIAEATEAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE38C95 +--DADVRLAALEKATGGRLGVSVLDVAMNISF-GRRQEERFAMCSTFKMLAAACILARVD +NGEERLDRKIAYSKADLVDYSPMTENHTEDGMTVAELCEAAVTVSDNTAANLLLASMDGP +EGLTRWLRGIDDQVTRLDRIEPELNEAKKDDPRDTTTPHAMLTTMGKLLLDDALSDTSRD +QLTAWLVGNKTGDKRLRAGLPKAWKVGDKTGTSATGAIGDVAIVWPSPNRPILVTAYIAE +ATKPAKELEYIFAEIGKMV---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL WC-3626 TaxID=1463926 RepID=UPI0004C04656 +-------LTDLEREYGARIGVYAVATGTGATV-IHRADERLALCSTFKTLAAAAVLDRGP +--LTRLDRRVTYTRADLVPYSPVTGRHVDTGMTLRELCDAAVRHSDNTAANLLLRDIGGP +SALTAHLRGLGDRISRLDHTEPELNGNPPGDPRDTTTPRAVAADYRALVLGDALPAAKRA +LLTDWLVGSTTGGKRIRAAVPGDWKVGDKTGTGDWGRAHDIAVLWPPRGAPLVIAVLTEH +PDRDAAADDALVAEAARRT---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. BK387 TaxID=2512128 RepID=A0A4R2EAK2_9ACTN +--AAHAELAELEQRYGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDRA +-GCAPLDRVVHYPPHDLLPNSPRTEENLATGMTVADLCAAAIQYSDNAAGNLLLRELGGP +AGLTRFHRSLGDEVSRLDRWEPELNTAIPEDPRDTTTPQAIAASLERVTLGRALARADRE +RFIGWLKGNTTSSARFRKGLPKEWVVADKTGTGDYATANDIGVAWTTRRTPLVLAVLSGK +GTPDAPVDEALIADAAAVVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FA74_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTSKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVAEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia kururiensis TaxID=984307 RepID=UPI000F89CD9F +--SVRDALAALERTSGGRLGVCAIPTCKPREI-RYRADERFPFCSTFKVVLAAAILARSL +DVPDLMRRRIRYTKHDLAHYSPVSSKHVEDGMTVAELCQAAIQYSDNTAANQLMKVLGGP +QAVTAYAHATGNAAFRLDRWETELNTAIPGDLRDTSTPAAMARTLQTLTVGQALPSAQRD +QLVTWLRGNTTGAHRIRAGVPADWQVGDKTGTGDYGTANDLAILWPPGRAPIMLAVYFTQ +REPKAKARDDVIAAAARIVA--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFD0490 +-qATHKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKGDLVEYSPVTERHVDTGMTLGKIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMEDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN +ILTEWMKGNATGDKLIRAGVPNGWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIEEAAKVVID-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. G3(2015) TaxID=1706731 RepID=UPI0007385AF6 +---SHDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKKDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillaceae TaxID=186817 RepID=UPI00041B53C0 +--DIKATFSKLEKEFDARLGVFALDTGTNKTI-AYRSEERFAYASTHKALAVGALLQQKS +--MEDLEQRITYTKDDLVNYNPITEKHVDTGMTLKELSDASIRFSDNTAANLIFNQIGGP +SGLKDTLRGLGDEVTNPQRKEPALNEFTPGETADTSTPKALVTSLQAFTLGDVLPEEKRT +ILVDWLKRNTTGDNLIRAGVPSNWEVADKTGAASYGTRNDIAIIWPTKGDPIVLAILSDR +DKEDADYNDKLIAQATKKVIE-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia megapolitana TaxID=420953 RepID=A0A1I3RC63_9BURK +---AETLLAELERSSGGRLGVSALNTASGERI-GYRAEERFPFCSTFKLILSAAILARST +QDSGLMQRRIRYAASDLVSSSPLTTKHLAEGMTVGELCAATLQISDNTAANLLIKVLGGP +AEVTAYARSIGNESFHLDRTETTLNTAIPGDTRDTATPASMALSLQTLVLGESLPQAQRT +QLTAWLRANRLGDQRIRAGVPADWQVADKTGTGEHGTANDIGVLWRPTGAPIVLALYYTQ +GSEDEKVHSGVLAAAARIVASAf +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. 8-3EHSu TaxID=2510978 RepID=A0A4Q7J1I7_9PSEU +-----AEFGQLESRFAARLGVYAIDTGSGREV-AFRPDERFAFASTFKALAAAAVLRANT +--PAELDQIVRYTRADLQEHAPIAEKHVDTGMSLRALCDAAVRYSDNTAGNLLLNELGGP +AGLTRVLRELGDQTTRSDRMEPELNEATPGDPRDTSTPRALAGSLRTFALGDALAADKRE +IFVDLLRRNTTGDKVIRAGTPAGWVVGDKTGTADYGGRNDIAVIWPPGRAPIVLALLSAR +SSTEDQPQDALLAEATKVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFA8056 +----NQSFAKLEKEYDAKLGIYALNTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. b62 TaxID=1827627 RepID=UPI000BF19A3D +------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPDLSRWVPGEKRDTSTPRALAEDLRAFVLGKALHPPERA +QLMTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=UPI0009EB1575 +---TVNKFMQLEKKFDARLGIYAIDTGTNRTV-VYRPDERFAYTSTYKALAAGAVLQQNS +--IGELDEVITYTKDDLVTYSPITEQHVDTGMTLKEIGDAAIRYSDNTAGNLLLQELGGP +NGFENALRQNGDHVTEADRYETDLNSAIPGDIRDTSTARALATSLKAFTVDGILPNGKRT +LLTDWMRGNTTGDELIRAAAPKGWEVGDKSGAGDYGTRNDIAIIWPPNRDPIIIAILSSR +DTKDATYNNELIAKAAKVALSSf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BEF7932 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLCKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Ornithinibacillus sp. TaxID=1898027 RepID=A0A3C1I5A7_9BACI +-eSIDEKFAELENEFNARIGVYAIDTGTNQTI-EYRPEERFAFASTYKALAAAILLQQNS +--LEELEEVISFTEDDLVPYSPITEKHVDTGMTLLELSEAAVRSSDNTAGNLLYEGLGGP +KGFEQALRQIGDNITHADRFEPDLNAFTPGDNRDTSTPKAFATNLQAFTLGDVLSDEKRE +LFIDWLKGNATGDTLIRAGSPEEWVVGDKSGAGSYGTRNDIAIVWPPNREPIVIVIMSNH +DTENAEYDDKLIAQAAKVTL--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0011A5B19D +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDIGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF3AB72 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFTFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI00124B9717 +----DQEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT +--DAQLDRVVRYSARDLVAHSPITEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +AGFEAKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALEPADRD +VLRAWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DRKDATPDDAVIAQATRVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=UPI00103424CF +--MLRAQWAQIERGTGGRLGINLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP +AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRK +QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=UPI001034B2ED +--MLRAQWAQIERGTGGRLGINLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP +AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRK +QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9LAR8_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEAFPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERN-------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004CB61E2 +------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPDLSRWVPGEKRDTSTPRALAEDLRAFVLGKALHPPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2B4BJ63_BACTU +----NQSFAKLEKEYDAKLGIYAFDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKHLGGP +SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Azorhizobium doebereinerae TaxID=281091 RepID=UPI0004194CC9 +--ALADGIAALEAGSGGRLGVSVRDTGTGAGF-AHRGAERFPMCSTFKFLLAAAVLSRVD +QGRMDLSRVIPVTPADLVDYAPVVEKKVGQGLSVAALCDAAVTLSDNGAANLLLREIGGP +QAVTEFARALGDPVTRLDRNEPALNVVPPGETLDTTTPDAMLADLDALVLGHALSPGARQ +MLTGWLVGCRTGDKRLRAGLPQGWKVGDKTGTGPTGSANDVAVAWPPGRAPLLITSYLTA +SRLDGPGNDALHAAVARLVAQ-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus bataviensis TaxID=220685 RepID=K6CKQ2_9BACI +--HIHREFAELESKFDARLGVYAIDTGTNQTV-SYRPNERFAYASTYKALAAGALLQHYS +--IDQLEELVTYNSEDIVSYSPVTELHVDTGMTLREVIEAAVRYSDNTAGNLLLEKLGGP +EGFETALKQIGDKVTEVNRYEPDLNSAIPGDKRDTSTPKSLATSLQAFAVSDLLPTEKRK +ILTDWMRGNATGDALIRAGAPTGWEVADKSGAGSYGTRNDIAIVRPSNRAPIIIAVLSSR +DTQNATYDNTLIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000CD7EAAD +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEAFDQKITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SAFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus sp. 7884-2 TaxID=2022552 RepID=UPI000BA56C55 +-qTTDNDFAQLEKEFDAKLGVYALDTGSGKII-DYQADERFAYTSTFKPLAAGAVLKQNS +--FEELNETVTYTEDDLVTYSPITEKHVDTGMNLLEISEAAIRYSDNTAGNLLFNELGGP +DGLEKAMREIGDNVINSDRTETNLNEAKPGDVRDTSTPKALATSLQAFALDQLLSESKQD +MLLEWLKTNTTGDSLIRAGVPEDWTVGDKSGAGGYGTRNDIGIVWPPDREPIVIAILSNR +DTEDAEYNDDLIKQATEITVD-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas bromi TaxID=56449 RepID=A0A1C3NJJ9_9XANT +---LRAQWADIERGTGGRLGISLLDSATGWRL-GQRENERFPMCSTFKFVLAAAVLQRVD +EGKLTLAQPVKIRASDMLEHAPVTERHVGGALSVGELCRATMIYSDNPAANRLFPLVGGP +PGVTTFLRSIGDAQTRSDRHEPEMNRFAPDDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDLAILWPPKGPPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Jiangella gansuensis TaxID=281473 RepID=UPI00047897AC +-----DAVSALEQAYDTTIGLAARNLDTGARL-IHRAADRFPMLSVFKTLAVAAVLRDHD +EHGETLRRRVWYPPADVLEYAPVAAEHVDTGMTVAELCDATLRLSDNTAANLLLREIGGP +RGLTAFIRSIGDHVTRLDRWEPDLNTAVPGDERDTTTPAAIARAYAGLLTGTTLSRPDRN +RLTSWMLDNQTSDTRFRAGLPRGWRLADKTGSGAYGTNNDVGVAWSPDGTPVVIAALSRR +DRPDATGNDEVLAELARLVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000D51D327 +----DREFAKLEEKYDAHLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDEVTLPERFEPDLNEVNPGETHDTSTARALAASLQKYVLGQALPEDKRE +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGSGSYGTRNDIAILWPPKGDPIVLAILSDR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. LTSP857 TaxID=1619231 RepID=UPI0005D2B547 +------ELESYERESGGRIGVYAENLATGAKL-IWRADERFVMCSTFKASLAACVLARVD +RGEEQLAATIPYGQADLLDYAPIAKQNLATGMSVAEMCKAIIELSDNTCANLLLARIGGP +AALTAFWRSLGDATSRLDHNEPELNRSPPGDPHDTTTPAAMANNLRRLVTGEALSQASRT +QLTDWMVNCKTGANRLRGGLPADWKIGDKTGNNGKDASGDIAIVWPKPDRPILIAAYTQG +GTPTAAQIEAVFARIGRMVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora orduensis TaxID=1420891 RepID=A0A5C4QNS5_9ACTN +-----REFRLLQERFDARLGIYAIDTGTGRTV-RYRADERFGYCSTFKALAAAEVLDGTT +--DAELDRVVRYSADDLVTYSPITERHVADGMTLRAIADAAVRYSDNTAGNLLLRQLGGP +QRFEKELRGVGDSVTDPARYETELNEARPGDRRDTSTARALAQDLRAYVVGDALEPADRD +VLTGWLRGNTTGGELIRAGVPDGWVVGDKTGAGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEKDASYDNALIAQAAEVVIA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9LAR6_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDKVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERN-------------- +>[subseq from] Beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=O33677_SERMA +--ETLVKVKDAEDQLGSTSGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGS +QELTAFLHNMGDHVTRLDRWEPELNEAIPNDEADTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMADKVA-GPLLRSALPAGWFIADKSGARERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SM18 TaxID=1736046 RepID=A0A2S2GGQ5_9ACTN +--ETAEAFEKLEGEFDARLGVYAVDTGTGREV-THRADERFAYASTFKALAAGAVLRTYK +--VSGMDRVITYSENDLVPNSPVTEKHVGTGMTLDALCDAAVRHSDNTAANLLLDRLGGP +KGLGALLAELGDDVTRMERREPELSSWVPGSTRDTTTPRAFAGNLRAFVLGDVLGDAERA +RLTRWLRTNTTGDEVIRAGVPDDWTVGDKTGTGGYGIRNDIAVLWPPGRAPVVVAVLSNR +DGEDDAYDNRLLAKAAAVVVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF27D1C +----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--MEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus luti TaxID=2026191 RepID=UPI0012E743A7 +-qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNA +--MDKLNEVIKFTKEDLVEYSPVTKRHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEEALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNREPIIIAILSSK +DEKEATYDNQLIEEAAEVVVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Aureimonas sp. N4 TaxID=1638165 RepID=UPI000785A3D7 +--DLDALWAEIENRFSARLGAFVWDMETDRRW-ARRADERFPLCSTFKLVAAAGLLARVD +AGEENLSRRVVIAKSDLVTYSPETEKHVGGEMTLSSIAEAALTQSDNTAGNVLIDLLGGP +EGVTRTARGFGDETFRLDRRETALNEAKPGDPRDTTSPAAMTKMLHALLFGEVQKPDSRR +QLADWMVANRTGDAKLRAGLRKDWRVGDKTGGGDFGTMNDVAVIWPPAGKPILISLYLTE +TKASFDERNAAFAEVGRAL---- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas perforans TaxID=442694 RepID=UPI00115DAE2D +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRGD +QGKLTLAQQVRIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP +AGVTAFLRGIGDAQTRTDRYEPQMNRFADDDPRDTTTPAAMAATLRTLLLGDALHPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00101CF080 +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEVLENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. H1a TaxID=1397276 RepID=UPI0009E018E4 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--INKLNEVITYTKEDLVEYSPITEKNVGTGMKLGEIAEAAVRSSDNTAGNLLFNKIGGP +KGYEKALRQIGDRVTMAERFETELNEATPGDIRDTSTAKTLATNLKEFTVGNALPADKRK +ILTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR +DEKEATYNNELIAQAAEVVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus khoisanae TaxID=880157 RepID=A0A0J5FV31_9GAMM +--QLIHQLSILEKNANGRLGVVLIDTSDHSTF-AYRANERFPLCSTSKFMAVSALLKKNE +ANDHLLNQRIHYQQSDLVEYSPITEKHLKNGMTLRELGEATMQYSDNAAMNLILNQLGGP +NEVTQFARTIGDNDFRLDRKEPDLNTAIPGDERDTSTPQAMANSLYHLALGNTLETAQRE +QLVAWLKGNTTGGASIRAGVPENWVIGDKTGRCSYGTINDIAVIWPTNRSPLVLVTYFTQ +PNQNANARPDVLAEAARIVTQ-- +>[subseq from] Beta-lactamase n=7 Tax=Bacteria TaxID=2 RepID=A0A1U7AE39_9BACT +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPENKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=2 Tax=Pseudovibrio sp. Ad26 TaxID=989410 RepID=A0A165TV92_9RHOB +--ELMDTVTRLESEVGGRIGVVLQHTGSEWGI-EHREDERFPMASTFKALLCGAVLSRVD +RGEESLDDLVTYKATELVSYSPVTKNHVASGMSVGQLCEATVTMSDNTAANLLLKRVDGP +EGLTRFLRGLGDRVTRLDRNEPALNEAKHGDSRDTTTPSAVLKTLDRLLFEDVLLPSSRA +QLQQWMVDDKVADELIRKHLPKGWRIADKSGGGQNGSRGIISVIWPETGKPYLASVYMMG +SDASFKQRNAVIADIGKAMIE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=J9BF03_BACCE +----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDLRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKTLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALAISLQTYALGDILSTEKQN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKKDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase protein n=1 Tax=Agrobacterium radiobacter (strain K84 / ATCC BAA-868) TaxID=311403 RepID=B9JBH3_AGRRK +-eDADKQLADLEKKTGGRLGVSVLDTETNISL-GYREAERFALCSSYKALAAGFVLARVD +QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCNAAVTLSDNTAGNLLLDSFGGP +AALTAWLRTTGDTETRLDRKEPDVNQAIKDDPRDTTTPDSMLDTIGLLTLGNTLSETSRD +QLSNWLVANTTGNARLRAGLPKEWKVGDKTGTGENGSYADVAVIWLPDRGPILVVTYVGE +ATAPAKDIEAVFAEVGKIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Massilibacterium senegalense TaxID=1632858 RepID=UPI000AEC23DB +--NTDEKFTQLENEFDARIGVYAIDTGSNQTI-EYRSEERFAFASTYKALAAAILLQQNS +--LEELKEVITYTEEDLVTYSPITEKHVDTGMTLLELSEAAVRFSDNTAGNLLLEALGGP +KGFEQALREIGDNVTKADRFEPDLNYFTPGDTRDTSTPRALATSLQAFAVSDLLSNDKHE +LFTDWLKGNATGDTLIRAGAPEGWEVGDKSGAGGYGTRNDVAIVWPPNREPIVIVILSRH +NTEDAEYDDTLISQAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Modestobacter sp. KNN46-3 TaxID=2711218 RepID=UPI0013E0DCEC +---VGEALTALEGEFDARLGLYAVDTGSGQVV-AHRADERFGYASTHKALSAAAVLDRTS +--DAELDQVVTYTAEDLVPHSPVTEAHVGAGLPLRELAAAAVQHSDNTAANLLFDRLGGP +AGLEQALRDLGDDVTSVDRTETALNTAVPGDVRDTSTPRALATDLQAVLLGDALDPADRD +LLTGWMRDNATGGTLVRAGVPADWQVADKSGGGGHGTRNDIAVVWPPDGAPIVLAVLSSR +DEADAEYSDALIARATDIAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. BPSDS2 TaxID=2571021 RepID=UPI0010C16F54 +-----EGFRKLEREFDARLGVYAVDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS +--LDGLDKRVTYTRENLVANSPVTEKHVDTGMTLEELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDRQEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIRAGVPKGWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF7CB29 +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPENKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Prauserella sp. YIM 121212 TaxID=1477506 RepID=A0A318LRD1_9PSEU +---AHREFGELEQRFDARLGVYAIDTGTGREI-AHRAGERFAYCSTFKALATAALLSERT +--VAELDVVVPYTEADLVTYSPVTEKHAGAGLPLREVMDAAVRYSDNTAGNLLLRELGGP +KGLQAALREVGDETTHVDRYEPELNEATPGDIRDTSTPRAMAGTLRAYALADALTAEKRA +IFVDMLRRNLTGDELIRAGVPDGWVVGDKTGNGDYATRNDIAVVWPPDRAPIVLALMSSR +SEKEAEHDNALLAEATKTVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=C2PWT7_BACMY +----NQSFVKLEKDYDAKLGIYALDTGTNQIV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYGLGDILSVEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH +AKEDTKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Tue 6075 TaxID=1661694 RepID=A0A1L6PTS1_9ACTN +------HFKELERKFDARLGVYAIDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAQDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPDDRLIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces glebosus TaxID=249580 RepID=A0A640SU30_9ACTN +---SAQAFKDLERKFDARLGVYAINTGTGREV-SYHQDERFAHASTFKALAAGAVLQKYS +--LPGMDKVITYSRDDLVPNSPVSEKHVDTGMTLRALCDAAVRYSDNTAANLLFDSIGGP +KGLDAVLEKLGDHTTRMVRHEPELNDWSPNDTRDTTTPRAFAKDLRSFVLGDTLPRRERA +QLAKWLQTNTTGAKLIKAGMPKTWLVGDKTGAGSYGTRNDIAVVWPPHAAPIVVAILSNR +TQKDAKYDDALIARAASVVA--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000851D5E4 +------DFKKLEREFDARLGVYAIDTGTGREV-THNDRARFAYHSTFKALQAAVVLSTYS +--LDGLDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDITRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPDDELIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A150C8D9_BACCE +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGSLLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKTLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSFGTRNDIAIIWPPNKKPIMLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. NXC24 TaxID=2048897 RepID=A0A2L0W895_9RHIZ +--DADKQLADLEKKTGGRLGVSVLDTETNISL-GYREAERFALCSTYKALAVGFVLARVD +QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCGAAITLSDNTAGNLLLDSFGGP +AALTAWLRTTGDTETRLDRKEPDVNQAIKDDPRDTTTPDSMLDTIGLLTLGNTLSETSRD +QLTNWLANNTTGNARLRAGLPKEWKVGDKTGTGQNGSYADVAVIWPTDRGPILVTTYVGE +ATAPAKDIEAVFAEVGKIIA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Rc2d TaxID=1855321 RepID=A0A1G8UE41_9BRAD +------ELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGQADLLEYAPVAKQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSIGDTTSRLDHNEPELNRSRPGDPRDTTTPAAMAGNLRRLVLGDALSPASRA +QLTEWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPRPDAPILIAAYTQG +GTPSAAQIAAAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9AWU0_BACCE +----NQSFVKLEKEYDAKLGIYALDTGLNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IKDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRDIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKKNTTGDNLIRAGFPGEWKVADKTGSGPYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. S3 TaxID=486398 RepID=A0A513RN08_9BACI +--QLHRKFAELENKYDARLGVYAIDTGTNRKV-SYRPQERFAYASTYKALAAGALLQHYS +--MDQLDELVTYNSEDIVSYSPVTQLHVDTGMTLWEVAEAAVRYSDNTAGNLLLEKLGGP +EGFETALRQIGDHVTQADRYETDLNSAVPGDKRDTSTPKALATSLQALAVSDLLPTEKRT +ILIDWMRGNATGDTLIRAGAPTGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR +DTQNATFDNTLIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Hyphomicrobium sp. NDB2Meth4 TaxID=1892846 RepID=UPI00093141CA +--DIDATLAEIEAGIKGKLGVAIIDTKTGELY-ARNQFERFPLCSTFKLLAVALVLVRVD +NGEEKLDRHIVIAKDEIVPYSPVTEKQVGGEMTIAALCEAAISRSDNTAANVLLKTLGGP +EALTNWLRTLGDKATRLDRAEPALNDVPEGDFRDGTTPRAMAYTVQRILLGNVLSKTNEK +QLLDWLIANKTGDARLRAGLPSDWRVGDKTGTCK-GTTSDVAIVWPPNHPPLIIAAYLTA +PGASPEAREKALAAVARAAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Stappia indica TaxID=538381 RepID=UPI0009F49B9E +--DIEGRLAALERKQGGRLGIAIHDVASGQTF-GNRLNERFLMASTFKLMLAAFVLARVD +REEEQLDRRIPFTKRDLVSWSPGTEKHAGGPLTVAELCEATMTMSDNTAANLLLASFGGP +AALTGFARSLGDETTRHDRTEPALNADGPDDERDTTTPGAMAETLRKLLFGDALSRRSRD +RLTAWMVTNRTGDARLRAGFPADWLVGDKTGTSGKGHANDIGVAWPSSRGALIVTAYCEM +PKAEAKTRDATMAEIARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Gracilibacillus sp. SCU50 TaxID=2663022 RepID=A0A5Q2TQ15_9BACI +---IDEEFAQLEGEFDARLGVYAIDTGKNQIV-EYNPDERFAYASTFKVLAAATLLKQNE +--IKDLEKVVTYSKEDLVTYSPVTEKHVDTGMTLLEISEAAIRKSDNTAGNLLLEALGGP +NKLEQALRDIGDDVTEPERYETELNEFTPGSESDTSTPRAMATNLKKVALDDFLPNEKRE +LLIDWMKGNATGDALIRAGQPEEWVVGDKSGAASYGTRNDIGIVWPPNREPIVIAVMSRH +DTQDAEYDDELVAKAAEIT---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Salmonella enterica subsp. enterica serovar Altona TaxID=1151173 RepID=A0A140GPJ5_SALET +--ETLVKVKDAEDQWGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCAAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQ--------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Phytoactinopolyspora halotolerans TaxID=1981512 RepID=UPI0013D2064B +---TDALFAALENEFDARLGVYAVDTGSEITV-TYRSDERFAYASTHKALSAAVLLDQNS +--LADLDEVITYDADDLVAHSPVTEQHVRTGMTLRELCDAALRFSDNTAANLLLAEIGGP +DGLDRALAEIGDDTTSVDRWETALNEATRGDIRDTSTPRALATDLRAFALGDALPAEKQE +LLIDWMRRNTTGDTLIRAGVPDGWEVGDRSGGGGYGTRNDIAVIWPPGDDPIVMAVLSSR +DAEDAEYDDALIAEAAELAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Halotalea alkalilenta TaxID=376489 RepID=UPI0005B88CDC +-------AREIEQRLEARVGLAIYDTGSNQSW-LYKADERFPMASTFKAFACATLLHQVD +AGGRDLDQTVALAEADLVPYAPVMEKLVGQRVSLGELCAATMRTSDNLAANKVLDSIGGP +QQVTAFMRSIGDDTTRLDRREPELNQATPGDMRDTTSPAAIATSLRELVLGDALSASSRA +RLTAWLVENEVGGPLLRSGIPQDWRIGDRTGAGGYGSRGVVAVIWPPEREPIVAAIYLTG +TNATMDERNAAVAELGEALA--- +>[subseq from] Beta-lactamase class A n=2 Tax=Microbacterium sp. SLBN-1 TaxID=1489561 RepID=A0A542GRB8_9BACI +-----ETFANIEDKYDARVGIYAIDTGSDRTI-DYRSEERFAFTSTYKALAATLVLKQNT +--MEELEEVITYTEDDLVSYSPITEKHVDTGMTLSELGEAAVRTSDNTAGNLLFEELGGP +EQFQQSLREIGDDVTQADRYETALNEFTPGDPRDTSTPAALATSLQGFAVGDLLPDDKRK +ILIDWLKGNATGDTLIRAGAPEGWTVADKSGAGRYGTRNDIAVVWPPDREPIILAIMTRH +DTEDADYDDALIAEVAEVTLE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2K4_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQT +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSIVAILWPPGQAPLLAAIYLTQ +SDASMEQRNAAIAAIGTALAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Prauserella sp. YIM 121212 TaxID=1477506 RepID=UPI000D76E816 +---AHREFGELEQRFDARLGVYAIDTGTGREI-AHRAGERFAYCSTFKALATAALLSERT +--VAELDVVVPYTEADLVTYSPVTEKHAGAGLPLREVMDAAVRYSDNTAGNLLLRELGGP +KGLQAALREVGDETTHVDRYEPELNEATPGDIRDTSTPRAMAGTLRAYALADALTAEKRA +IFVDMLRRNLTGDELIRAGVPDGWVVGDKTGNGDYATRNDIAVVWPPDRAPIVLALMSSR +SEKEAEHDNALLAEATKTVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia otitidiscaviarum TaxID=1823 RepID=UPI0007C700D0 +-----DSFASMESERAARLGVYAVDTGSGRTV-AYREGERFPMASTFKGLACGALLRDHP +LSTGFFDQVIHFSRDELVEYSPMTEQRVDTGMTVAELCEATITLSDNTAGNKVLELLGGP +AGFTAFLRSIGDEVTRLDRWETELNSAVPGDERDTTTPAALAADYRALVLGDVLGEPERA +QLKSWLVANTTGDQRIRAGVPADWTVGDKTGSPAYGGTLDVAIAWPPGLAPIVIAVLTAK +SEPDAEPDNALVVDATRAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE12344 +--DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD +QGMEKLDRRVTYGKDKVVTYSPATEKHADTDMTVGELCGAAITLSDNTAGNLLLESFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAAKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVANTTGNNRLCAGLPKEWKTGDKTGTGNNGSYADIAVIWPPDRGPVLVTTFVAD +ATAPAKDVETVFAEIGKIVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000A11DE33 +-----KKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAVPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIILAILSNR +FTKDAHYDNALIAEATKVVLN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI21_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVXDKTGAGDYGTTNXIAVIWPEDHAPLVLVTYFTQ +PH--------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000E1EA869 +---LRAQWAEIERGTGGRLGISLLDSATGWRI-GQRENERFPMCSTFKFVLAAAVLQQVD +RGKMPLAQPVKIGASDMLSHAPVTERHVGSALSVGELCRATMIYSDNPAANLLFPLVGGP +PGVTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAGRDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0008728BDE +----NHSFVKLEKEYDAKLGIYALETGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDLRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKQN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADVTKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. LK2 TaxID=1628206 RepID=A0A0J6L6Q7_9BACI +----NQSFVKLEKKYDAKLGIYALDTGLNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IKDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKKNTTGDNLIRAGVPGEWKVADKTGSGPYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIAGATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinobacteria bacterium OK006 TaxID=1592326 RepID=UPI0006BB2E17 +--DTRARLRELEARHGARIGAFAYNLRTKATV-RHRAAERFPLCSVFKTLAAAAVLRDLD +RHGETLARRIHYTAADLAGYSPKTGEHLASGMTVGELCDAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PAQDAAPDSPLVAAAASLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF6C10D +----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPGDIRDTSTPMALATSLQTYALGDILPIEKRN +FLIDLMKRNTTGDNLIRAGAPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDVKYDDKLIADATKIVLN-- +>[subseq from] Beta-lactamase (Penicillinase) n=1 Tax=Xenorhabdus bovienii str. kraussei Quebec TaxID=1398203 RepID=A0A077PCE2_XENBV +-nQITNQLSALEKNANGRLGVVLIDTADHSTI-TYRAHERFPLCSTSKMMAVSALLKKSE +TDEGLLNQRIHYQQSDIVEYSPITEKHLQDGMTLAELSAATIQYSDNTAMNLLIDQLGGT +HDVTRFARSIGDNSFRLDRKEPELNMVTPGDERDTTTPQAMADSLYKLALGNTLAATQRT +QLVEWLKGNTTGGASIRAGVPDNWIVGDKTGRCDYGSTNDIAVIWPDDKAPWILVTYFTQ +PNKDAEAHPDVLAAAARIMTQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000E2F9D23 +--KSDQEFAKLEEKYDANLGVFALDTGTNKTV-TYHSDERFAYASTHKALAVGALLQRKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia sp. TaxID=1884818 RepID=A0A5B9T713_9ESCH +------EVKDVEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQ--------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Pectobacterium versatile TaxID=2488639 RepID=UPI00102F1AE1 +-pDTLNTVKDAENKLKARVGYTELDLTNGMILeGYRPEERFPMMSTFKVLLCSAVLSRVD +SGKEQLDRRIHFHQSDLVTYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLSTIGGP +QELTIFLRKAGDHVTRLDRWETALNEALLGDERDTTTPKAMAETLHKLLTGKILTVASQQ +QLMDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYLTG +GQATIEERNKQIAEIGTSLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Micromonospora taraxaci TaxID=1316803 RepID=A0A561W3K4_9ACTN +--AAEQEFQRLEKTFGARLGVYAVDTGTGRTV-EHRSDERFAYASTWKALAAAEVLDDTT +--DAELDRVVRYPARDLVAHSPITEKHVAEGMSLRAVADAAVRYSDNTAGNLLLRHLGGP +EGFERKLRAVGDTTTDAARYETALNEATPGDRRDTSTARALAGDLRAYTVGDALTPADRD +VLRGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DTKDATPDDALIAEATRVVVA-- +>[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI0003423B24 +-tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRASVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVMK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-455 TaxID=1463908 RepID=UPI0004BF4D29 +----TARLRELEQEHTARLGVYARDMRTGRTV-AYRADERFPMASLFKTLAAAAVLRDLD +RDGEFLARRVYFTQDDVDKYSEVTKHHVATGMTIGELCDATIRFSDNTAGNLLLEELGGP +TAVTRFCRSIGDPVTRLDRWEPELNSAEPWRVTDTTSPRAIGTTYARLVLGTALEPRDRG +RLTDWLLGNTTSVERFRKGLPADWLLADKTGGGQYGSNNDVGITWPPGGTPIVLSVLTTQ +PEEDAPADNALVARTAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00119E23ED +--KSDQEFAKLEEKYDANLGVFALDTGTNKTV-TYHSDERFAYASTHKALAVGALLQRKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Saccharomonospora cyanea NA-134 TaxID=882082 RepID=H5XLN5_9PSEU +---VRAELRALESRHAARLGVHAINIRSGAVV-SYRAHERFPMCSTFKTLAVAAVLRDLD +HDGEFLDSWVHYTEDDLVPNSPVTENHVGRGMRVEQLCAAAIRKSDNTAANLLLRRLGGP +GGVTRFCRSLGDPVTRLDRYEPELSDAVPGDPRDTTTPAAIAADYRRLVLGRALCPADRE +RLTTWLTESVTSDTRFRAGLPSHWRLADKTGSGGYGTANDVGVAWTGDGAPLVLAVLSTK +HVEGAEWDDELVARTASVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A068N7C4_BACCE +----------------ARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKDLTVGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIAEAAEVVVNAf +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A1B1WXK4_ACIBA +---VLEAVTNAETELGARIGLAVHDLETGKRW-EHKSNERFPLTSTFKTLACANVLQRVD +LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP +KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ +QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE +TDASFEERNAVIAKIGEQIAK-- +>[subseq from] Beta-lactamase n=6 Tax=Bacillus TaxID=1386 RepID=A0A2A9YG25_BACCE +----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000B4127ED +----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000BEDA2C0 +----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=A0A0M1MQA2_9XANT +--MLRAQWAEIERGTGGRLGINLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP +AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRK +QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A059WWD7_9BACT +----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000B4365CF +-----KKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAVPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIILAILSNR +FTKDAHYDNALIAEATKVVLN-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces eurocidicus TaxID=66423 RepID=A0A2N8NUG6_STREU +-qEAERAFGELESEYDARLGVYAVDTGSGRSV-AHRPDERFAYASVCKAFLAGAVLRKNT +--LQQLDRRVRYGRDVPVGHSPVTAEHVGGGMTLRELCDAAVRHSDNGAANLLFDELGGP +KGLQDALAAIGDHVTRADRYETDLSEAAPGDPRDTSTPRAMAADLRAFVLGDALAADRRP +LLTDWLKRNTTGDTLIRAGVPAGWQVGDKTGSGGYGARNDLAVLWPPRAAPLVVAVFSGR +TAKDAKADDTLIARAAEAAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BEC645F +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKYVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPENKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. Root1220 TaxID=1736432 RepID=A0A0Q6UC44_9RHIZ +-dEIERRMGALEKAIGGRIGVSAMDTKTSISF-GYRQTEPFPLCCTFKVLAAGLVLARVD +KGEESLERRVVYAKEKLVSYSPETERHVGGEMSVGDLCKAAITLSDNTAGNLLLESFGGP +KELTNWLRTLGDGSTRLDRWETDLNEAKDGDPRDTTTPDAMLDTLGNIALGTVLSEPSQD +QLAEWMVASTTGGARLRAGLPDTWKAGDKTGTGDNGSAADVAIIWPPGHGAILVAAYMTQ +TTAPMSEINPVFAEIGRIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000CDB51C9 +--ELRYKWAEIERGSGGRLGIGLLNSDTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLVGDP +PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAGRDAALKAVAAAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF732D2 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILKEMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A242XBH6_BACTU +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFVSTYKALAAGVLLQQNS +--IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP +KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVLVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. 2MFCol3.1 TaxID=1246459 RepID=UPI0003684D58 +--EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD +KGEENLERRVVYEKEQLIAYSPETEKHVGGEMSVGDLCKAAITLSDNTAANLILESLGGP +KELTNWLRTLGDGSTRLDRIEPDLNDIAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK +TLIEWMVANTTGNERLRTGLPETWKIGDKTGTGKSGSAADIAICWPPGHGPILIAVYVTN +ATVATAEINPVFGEVGRIVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004BDBA14 +--DTADAFEKLEAEFDARLGVYAVDTGTGREV-THHADERFAYASTFKALAAGAVLRTYK +--VSGMDRVITYSEDDLVPNSPVTEKHVGTGMTLGALCDAAVRYSDNTAANLLLDQLGGP +KGLGALLAELGDGVTRMERREPELSRWVPGSTRDTTTPRAFAENLRAFALGDVLGDAERA +RLTRWLRTNTTGDEVIRAGVPDNWSVGDKTGSGGYGIRNDIAVLWPPDRAPVVVAVLSNR +DGEDDAYDNRLLAKAAAVVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax kalamii TaxID=2004485 RepID=A0A235EJL7_9BURK +--AWNDALATIERSAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD +QGRERLDARVHYVATDVVAYSPVSGPRAGNGLTVGELCAATVSLSDNTAANVLMARHGGP +AGFTAFVRSLGDQVTRLDRTEPTLNEAAAGDPRDTTTPLAMLQTLQKLVLGDALSPASRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPPGGAPVLVTCYLTR +STASAEQRDAAIAQVARAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Cmuel-A718b TaxID=697328 RepID=A0A1C5D9A2_9ACTN +------DFKKLEREFDARLGVYAIDTGTGREV-THNDRDRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +GGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A243GP90_BACTU +----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKKDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000942A2D3 +-qATHKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPEDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. OspMP-M45 TaxID=1115570 RepID=A0A1A9CY88_9ACTN +--DTADAFEKLEAEFDARLGVYAVDTGTGREV-THHADERFAYASTFKALAAGAVLRTYK +--VSGMDRVITYSEDDLVPNSPVTEKHVGTGMTLGALCDAAVRYSDNTAANLLLDQLGGP +KGLGALLAELGDGVTRMERREPELSRWVPGSTRDTTTPRAFAENLRAFALGDVLGDAERA +RLTRWLRTNTTGDEVIRAGVPDNWTVGDKTGSGGYGIRNDIAVLWPPDRAPVVVAVLSNR +DGDDDAYDNRLLAKAAAVVVR-- +>[subseq from] class A beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=UPI000353B2E1 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMRDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T7F8_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQT +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLIAAIYLTQ +SDASMEQRNAAIAAIGTALAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009AE2183 +-----KKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRLETDLNSAVPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIILAILSSR +FTKDAHYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0K0N4E3_ECOLX +-----VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQ--------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE1DB79 +---ADVRLATLEKATGGRLGVSVLDVAMNISF-GRRQEERFAMCSTFKMLAAACILARVD +NGEERLDRKIAYSKADLVDYSPMTENHTEDGMTVAELCEAAVTVSDNTAANLLLASMDGP +EGLTRWLRGIDDQVTRLDRIEPELNEAKKDDPRDTTTPQAMLTTMGKLLLDDALSDTSRD +QLTAWLVGNKTGDKRLRAGLPKAWKVGDKTGTSATGAIGDVAIVWPSPNRPILVTAYIAE +ATKPAKELEYIFAEIGKMV---- +>[subseq from] Beta-lactamase n=1 Tax=Labrys okinawensis TaxID=346911 RepID=A0A2S9Q965_9RHIZ +---FAGAIRRIEGGVGGRLGVAALDLKSGVRL-AYRSDELFPLCSTFKLLVAAAVLARVD +QGRERLSRQVPIEAARLLPNSPITARHAGGRLTLAELCAAAITVSDNLAGNLLLEVVDGP +AGLTRYLRSIGDLVSRLDRWEVELNESLPGDPRDTTSPAAMLADLQRLLVGEALSPSSRS +RLTAWLKASRTGDTRLRAGLPAEWAFGGKTGTGERGSTNDVAIAWPPGRPPLLIAAYLTG +TTAAADRRNAALAAVAKAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas monteilii TaxID=76759 RepID=UPI0011A397A7 +--AVRQRLATLERTHGRTLGLWALETGSGQRL-AYRADQRFAFCSAFKVLLAGAILQRNE +AEPGLLAQHIDYDAATLVTYSPITQDHLETGIRVADLCAAALQYSDNTAANLLLAQVGGP +AGLTAFARRLGDVVFRLDRDEPTLNTALPDDPRDTTTPLAMGMTLERLLVGKALTVPSRH +QLQAWLEGNTTGASRIRAGVPGDWRVGDKTGTGDYGVANDVAIVWPPGRAPWIVVVFTRG +PDPSSSGDSALIAAAMREVVGV- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI00097159A7 +-tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFHPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVMK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BAG5X1-1 TaxID=1053189 RepID=J8ATP3_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSEQVEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=UPI0005BA8EEC +---TARQLAELERNAGGRIGVFAQEVDSGRSL-AYRANERFPMCSTFKLLLVGALLQRSA +TQPDLLYRHVSYRREQLIDYSPIAEQYVEQGMSVKDLCDAAMRFSDNTAANLLLEELGGP +QEVNRFARSLGDGLTRLDRIEPELNRAEPGDPRDTTTPAAMTANLHALLFSPLLPERQRG +LLNDWLLGNTTGNLRIRAGLPAEWRVGDKTGSGGHGAANDVAVAWRPGKSPLLLSVFYWG +SPAMMDERNAVIAAVARVAAAEf +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas hortorum pv. hederae TaxID=453603 RepID=A0A2S7E0N6_9XANT +---LRARWAEIERGTGGRLGIGLLDSATGKRI-GQREDERFPMCSTFKFVLAAAVLRRVD +QGKLTLAQRVKIRASDMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP +QGLTAFLRGIGDTQTRSDRHEPEMNRFAQDDPRDTTTPAAMALTLRTLLLGDALQPVSRK +QLSDWMIDNRTGDTCLRAGLPRSWKIGDKTGSNGTDTRNDIAILWPSKGAPLLLTTYLNG +ASVDSDARDAALKAVAQAVASY- +>[subseq from] class A beta-lactamase n=1 Tax=Comamonas badia TaxID=265291 RepID=UPI0003F74AEF +-------WQAIETASQGRLGVAVLDVASGAFS-GNRLDERFPMCSTFKWLAAAQVLQRVD +QGHEQLKRRVRFGKEVLLPWSPVTEQHVDDGMTVGELCQAAVAMSDNAAGNLLLQSLGGP +RGLTRFAREQGDSVTRLDRWEPQLNESTPGDPRDTSSPRAMAGLLQRLVVGQALSRGSRE +QLAQWLRDTKTNAQRLGAGLPALWRVGSKTGTGPHGSTNDVGVYWREGRPPIVVVAFLTE +SAASLAVRETAIAQVAKAVF--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodobacteraceae bacterium LNNU 3342 TaxID=2605434 RepID=UPI00123CA4C0 +--TIAEAARAIEADLGGRVGVALRRKGDGEVI-GYRSDERFPLSSTFKAPLCGAILALVD +AGEEKLDRVVGYTADDLVTYSPVTETQVESGMSVAELCDATITLSDNTAGNLLLERVGGP +EGFTGYLRAIGDETTRLDRWETELNEGAPGDDRDTSTPEAMTATLEALLFGETLSEASRR +QLEAWMQADQVADELLRASLPEGWVIGDKTGAGGHGSRSIIAVIRPPHDEPWLAAVYLTG +NAADMPTRNRAIARIGAAIV--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B1V8Q7_BACCE +----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKKDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2U9IA12_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETGLNEALSGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQI----------- +>[subseq from] class A beta-lactamase n=2 Tax=Xenorhabdus khoisanae TaxID=880157 RepID=UPI00069ED321 +--QLIHQLSILEKNANGRLGVVLIDTSDHSTF-AYRANERFPLCSTSKFMAVSALLKKNE +ANDHLLNQRIHYQQSDLVEYSPITEKHLKNGMTLRELGEATMQYSDNAAMNLILNQLGGP +NEVTQFARTIGDNDFRLDRKEPDLNTAIPGDERDTSTPQAMANSLYHLALGNTLETAQRE +QLVAWLKGNTTGGASIRAGVPENWVIGDKTGRCSYGTINDIAVIWPTNRSPLVLVTYFTQ +PNQNANARPDVLAEAARIVTQ-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=A0A193BWT1_AMYOR +--QFHDRLLELEKKFDARLGVYALDTEGGATV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVTYARDDLMKHAPVTGQHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +GELTAFARSIGDTVTRMDRIEPAITEAAPGDPRDTTTPRAFGTDYQKIVLGDTLTADKRD +FLSDLLRRNVTGARRIRAGLPGGWTVADKTGTGEYGTMNDFAIVWPPGKAPIVVAIMSSK +AAKDAPYDEALLAEAAKYVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI00114E3170 +----NHHFAKLEEKFDAKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEELNQRITYTREDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP +TGFKKALEEIGDNVTNPERFEPDLNEVNPGETHDTSTPRALATSLQDFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDISIIWPSKGDPIVLVVLSSR +DKKDADYNDDLIAETTEEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI0006E17E35 +--KARRAFVRLERKFDARLGVYALDTGSRRSI-AHRADERFAYCSTCKAFLAGAVLKQNS +--LREMERRVRVRPQDLEDYSPIARKHVGSTMSLRELCDAAVRYSDNAAANLLFRELGGP +KGLQDALRDIGDRVTRADRYEVELSEGTPGDSRDTSTPRALATDLRAFVLGDVLPGKKRE +VLTDWLKRNTTGDKLIRAGAPRGWEVGDKTGNGGYGTRNDIAVLWPPKGDPVTLAVMSRR +DTRDAEHDDALIAEAAEVAL--- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudorhodoferax soli TaxID=545864 RepID=A0A368XD71_9BURK +haQAERALAALEQGFAGRIGVCALDTADGALL-GQRADERFPMCSSFKAVLAAAILARSS +TEPGLLAEQVRYTRGDLLAHSPVTTQHLAQGMRVDALCEATVQTSDNAAANLLLQRMGGP +AGLTAFMRSIGDAQFRLDRWELELNSSLPGDPRDTTTPRAMADSLRKLVVGDALAPAQRD +QLATWLRGTVTGAARIRAGMPAGWVVGNKTGTSGYGSAIDVAVVWPPARAPLVLTVFTTR +HAADAQALDAPIAQAARIAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0007CC0F71 +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDKGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPENKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces netropsis TaxID=55404 RepID=A0A445N4B3_STRNE +----AGEFKELERKFDARLGVYAIDTATGREV-AYNDGERFAHASTFKALAAGAVLRKYS +--LSGMDRVVTYSKDDLVDYSPVTEKHVETGMSLDELCDAAVRFSDNTAGNLLLDALGGP +KALDAALEEMGDHETRMERREPELNRWAPGGTQDTSTPRALAKDLRAYVLGDALGKSEKA +RLTKLLRTNTTGNELIRAGVPKGWVVGDKTGAGQYGTRNDIAVVWPPDAAPIVMAIMSNR +NKKDAPYDNKLIAEAASVVT--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8Z162_BACCE +----NQSFVKLEKEYDAKLGIYALNTGLNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IKDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKLLRDIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKQN +FLIDLMKKNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=unknown TaxID=N/A RepID=UPI00143E7BB5 +---SAQAFKDLERKFDARLGVYAIDTGTGREV-SYHQDERFAHASTFKALAAGAVLQKYS +--LPGMDKVITYSRDDLVPNSPVSEKHVDTGMTLRALCDAAVRYSDNTAANLLFDSIGGP +KGLDSVLEKLGDHTTRMVRHEPELNDWSPNDTRDTTTPRAFAKDLRSFVLGDTLPRRERA +QLAKWLQTNTTGAKLIKAGMPKTWLVGDKTGAGSYGTRNDIAVVWPPHAAPIVVAILSNR +PQKDAKYDDALVAEAASVVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. X1(2014) TaxID=1565991 RepID=UPI0011A4C0A3 +--HIHREFAELESKFDARLGVYAIDTGTNRTV-SYRPHDRFAYASTYKALAAGALLKHYS +--IDQLNELVTYNSEDIVSYSPVTQLHVDTGMTLREVIEAAVRYSDNTAGNLLLEKLGGP +KGFETALRQIGDNVTQVDRYEPDLNSALPGDTRDTSIPKSLATSLKAYAVSDLLSMDKRK +ILTDWMQGNKTGDALIRAGAPTGWKVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR +DTKNATYNNTLIAEAARVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. CMU55-4 TaxID=2717028 RepID=UPI00140A7C12 +-----AELAALERRFGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFARALRDVGDRVTRPVRIEPELNAATPGDERDTSTPRALAGSLRAYTLGEALPPADRD +LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDSAPIVLAVMSSR +GSRDAKPDDTLVAEAARATV--- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DC028C5 +----DQEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT +--DAQLDRVVRYSTRDLVAHSPVTEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +AGFEAKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALEPADRD +VLRAWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DRKDATPDDAVIAQATRVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFC9EFB +----HNSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEGAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A4R1EQ42_BACCE +----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLRKIGDSVTNPERFEPELNEVQPGDIRDTSTPMALATSLQTYTLSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +ANEDAKYEDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS017274 TaxID=2033488 RepID=A0A2A8TJC4_9BACI +----NHHFAKLEEKFDAKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEELNQRITYTREDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP +TGFKKALEEIGDNVTNPERFEPDLNEVNPGETHDTSTPRALATSLQDFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDISIIWPSKGDPIVLVVLSSR +DKKDADYNDDLIAETTEEVMK-- +>[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces TaxID=1883 RepID=A0A542WCM2_9ACTN +------SLTDLEREYDARLGVYALATGTGATV-VHRADERFAFCSTFKTLAASAVLDRDP +--LSRLDRRVTYTRADLVPHSPVAEKHLATGMTVRQLCDAAIRFSDNAAANLLLRDLGGP +RAVTAHLRRLGDRVSRLDQSEPELNGNPPGDPRDTTTPRAVAADYRALVLGDALPGAKRD +LLADWLVRNTTGGRRIRAGVPRDWRVGDKTGTGEWGRVNDVAVLWPPSGAPLVMAVLTDR +PGRADTTDEALVAEAARRVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFC6B55 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKLVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2V2H6I9_BACTU +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPEDVHDTSAPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKRA---- +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillus ihbetae TaxID=1870820 RepID=A0A1B2DYU7_9BACL +----DSLFKSLENEYDARLGVYAIDTGSGETI-AYRADERFAYTSTFKALASGAVLLQNS +--IEEIDEVISYSAEDLVTYSPITEKHVSTGMTLRDIMDAAIRYSDNTAGNLLLEQLGGP +EGFEAALRQIGDTVTQADRYETELNEAVPGDDRDTSTARALATSLNAFALGDVLPKDKQT +ILTDMLRGNTTGDELIRAAVPEGWAVGDKTGAGSYGTRNDLAIVWPPEGDPVVLAVLSSR +DTQDAEYDNALIAKAAEAAL--- +>[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI00102DCF72 +-tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKGAKYDDKLIAEATKVVMK-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. (strain L5) TaxID=648999 RepID=UPI0001C45D0B +------ELAALERRSGARIGVFALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP +AGFERALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD +LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSW +DSRDAEPDDALVAQAARVTV--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF8B47E +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEGTPGYIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. raphani 756C TaxID=990315 RepID=G0CCH4_XANCA +--ELRYKWAEIERGSGGRLGIGLLNSDTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP +PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAARDVALKAVAEAVR--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ncost-T10-10d TaxID=1839774 RepID=A0A1C5EN82_9ACTN +-----AQFAALERKHGARLGVYALATGSGLSV-AYRADERFAFCSTFKALAAAAVLHRNP +--LSHLDTRVTYTKADVNSISPITKDHIATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP +AQLTAYLRELGDTTSRMDQYEPELNRDRPEDPRDTTTPRAIAADYRKLVLGDALTAGRRA +LLKDWLERNLTGAKRIRAGLPEGWAVADKTGTGDYGRANDIAIVWPPHTTPLVVAVMSDR +PGYDTPPKDALIAEATTQIV--- +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Salmonella enterica I TaxID=59201 RepID=A0A0S2IHT3_SALTM +--------AELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYST- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI0004F13DD5 +-tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFSPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVMK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1G6IHS6_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPEDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas gei TaxID=1395960 RepID=A0A4S1X984_9SPHN +--EFRNAVGAVERASGGRLGLSILDTATGDRF-GWRASERFPMCSTFKFALAAAILKQVE +AGRETLDRRIKVAAADIVSNSPFCEKRVGASASVRELCQATITLSDNSAANLLLRTIGGP +DGFTRRLRAFGDPVTRLDRWETDMGEAKPGDVRDTTTPQAMADLARHLVLGRALAPTSRD +QLTAWMKDTRTSRTSLRAGLPAGWTVADKTGAGGYGTDNLLGIVWPPRRAPLVVASYITG +GSLPLEQSRPLHARVGRAIA--- +>[subseq from] UPI0010428532 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0010428532 +-tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFYPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVMK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. JKS001846 TaxID=1938743 RepID=A0A1W2GPU6_9BACI +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGL +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A0Q8EAV6_9ACTN +----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRGGERFAYASTFKALAAGAVLRRYG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAEPERA +RLAQWLTANTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +RDADADYDNTLIAKATSAAV--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A386UWD8_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNKVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinoplanes brasiliensis TaxID=52695 RepID=A0A4R6JBH2_9ACTN +-----QRFGELERRFGARLGVYALDTGNGRTV-THRADERFAHASTFKALLAAVLLRRLS +--DGDLRRVIRYTRADLLEWAPITEKHVKTGMTVDALIAAAVQHSDNTAANLLLRLTGGP +EGVQRELRKIKDNTTDLSRYEPTLNTAVPGDKRDTSTPRALGADLRAFVLGDVLPAPRRQ +KLTDLLLGNTTGDTYIRAGVPSGWKVGDKTGSGGYGTRNDIAVVWPPTGSPVIIAILSDR +GRPDAPSADALIAEATRAVVT-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=A0A328NRY5_9ACTN +--AADQEFRRLEEQFGARLGIYAVDTGSGRTV-EYRADDRFAYASTWKALAAAEVLDGTT +--DAQLDRVVRYSARDLVAHSPVTEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +AGFESKLRALGDTVTDVARYETVLNEGTPGDKRDTSTARALAGDLRAYTLGVALQPADRD +VLIGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DKKDATPDDAVIAQATRVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF29866 +----NHSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=UPI000949FED8 +--MLRSQWAEIERGTGGRLGINLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP +AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRK +QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0012938722 +---SDREFAKLEDKYDANLGVFALDTGTNKTV-AYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BFB65B3 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-TYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQKITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPETIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus chungangensis TaxID=1229152 RepID=A0A3D8PNG0_9BACI +--ATNNDFSKLEDEFDATLGVFALDTGTNETV-TYRPDQRFAYTSTHKALAVGVLLQQKS +--IGDLNQRITYTHDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQVGGP +SGFKKALREIGDNVTNPERIEPELNEVNPGETHDTSTPRALAISLQAFTLGDVLPTEKRA +LLIDWMKRNTTGDTLIRAGVPEGWEVADKTGAGLYGTRNDIAIIWPPKGNPIVLAILSDR +NTKDATYDDKLIEQATRVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DBF9EDE +----DQEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT +--DAQLDRVVRYSTRDLVAHSPITEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +AGFEAKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALEPADRD +VLRAWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DRKDATPDDAVIAQATRVVVA-- +>[subseq from] Beta-lactamase n=2 Tax=Nocardioides sp. SLBN-35 TaxID=512030 RepID=A0A542RTB7_9BURK +--EWNETLASIERIAQGRLGVAMLDTGSGLQL-GWRQDERFAMASTFKAVLAGWMLALVD +QGRERLDARVHYAATDVVAYSPVSGPRAGNGLTVGELCAATVSLSDNTAANVLMARHGGP +AGFTAFVRSLGDQVTRLDRTEPTLNEAAVGDPRDTTTPLAMLQTLQKLVLGDALSPASRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPPGGAPVLVTCYLTR +STASAEQRDAAIAQVARAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. A1 TaxID=148446 RepID=UPI000468E0F1 +--AASRQLDALEQGFDGRIGVAALDTGSGARL-LHRADERFPFCSSFKIMPVCALLARSA +KEPDLLSRVIRYRRQDLVINSPVTERHVDTGMSVAALCAAALQYSDNTAANLLIRLVGGT +AAVTAYARSIGDGSFRLDRMEIELNESVPGDARDTTTPAATAATLQRVLLGDALDASSRA +QLTDWMLGNRVGTARIRAGVPAGWRVADRTGTGAYATANDIAMLYPPHRAPIALAVYTTR +ERDNGDYDEARIAAVARVVVAAf +>[subseq from] class A beta-lactamase n=1 Tax=Lentibacillus sp. Marseille-P4043 TaxID=2040293 RepID=UPI000D0BDD35 +----DEKFAQLENEFDTRVGVYAIDTGSNQTV-EYQSDERFAYSSTFKVLAAAILLKQND +--IKNLEKVVTYTKDDLVTYSPVTEKHVNTGMTLLEISEAAIQKSDNTAGNLLLEAIGGP +DKFKQALRDIDDDVTQPERYEVELNEFMPGNKRDTSTPRAMATSLKKVALDDFLPDDKRE +VLIDWMKGNATGDRLIRAGVPEGWIVGDKSGAGSYGTRNDIAVVWPPNREPIVIVVMSRR +DTKNAEYDDALVAKAAKITLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0008645BD5 +----NQSFAKLEKEYDAKLGIYALDTGPNQTV-AYHSDDRFAFASTSKSLAVGALLHKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0008174623 +----NNSFAKLEKEYDAKLDIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLLQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGNALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI000C05B7CD +----NKKFVQLEKKFYAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +NGFEKSLKQIGDHVTKSNRFETELNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPKGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=UPI000289A97B +--AAQTQLAALEQGAGGRLGVAAWRHGSAQRV-AYRADERFPLASTFKAMLAAAVLARSV +SQPGLLEQRVRYEKKELVSYSPITEKHLAEGMNVADLCAATLQYSDNSAANFLMRLLGGP +QAVTAFARSIGNTLFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLEHSLPAVQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKNADTNEDIITAATRIAT--- +>[subseq from] Beta-lactamase n=1 Tax=Aureimonas jatrophae TaxID=1166073 RepID=A0A1H0MBJ1_9RHIZ +--RLDDVIRREESAIGARLGVAIHDTHDDVWW-RHRADERFPMCSTFKVLAGAATLKRVE +RGEEDLTRRISIAPDDIVTYSPVTEKRVGENMIMAEVLQAALTMSDNTAANILIDTLGGP +QSVTAFIRAIGDNTTRLDRRETELNEATPGDPRDTTTPEAMTRSLESLLLGNALQPTTRL +MLEGWMVANTTGGAKLRAGLPASWRVGDRTGGGAYGTMGDVAVIWPIDRKPVVASVYITE +TEASFDRRNEAIAAIGKALA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium etli TaxID=29449 RepID=A0A327XIG8_RHIET +--EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD +KGEENLERRVVYEKEQLIAYSPETEKHVGGEMSVGDLCKAAITLSDNTAANLILESLGGP +KELTNWLRTLGDGSTRLDRIEPDLNDIAKDDPRDTTTPDAMLDTLGNITLGSVLSEPSQK +TLIEWLVANTTGNERLRTGLPETWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTN +ATVTTAEINPVFGEVGRIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. JKS001846 TaxID=1938743 RepID=A0A1W2GQX5_9BACI +----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDTLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKKDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=H9AXM0_ACIBA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSRNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANILLTTIGGP +KELTAFLHNMRDHVTRLDRWEPELNEAIPHDERDTTMPAPVATTLRTLLTVELLTLASRP +RLIDWMEADKVAGPILRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. HIT-DPA4 TaxID=2615112 RepID=UPI001245D56C +---VTARLRALEAQHGARLGVFAHNLATRRTV-AHRADERFPVCSLFKTLAAAAVLRDLD +RHGETLARRVHYTADDLVENSKRTEEHLAEGMTIAELADAAIRYSDNTAGNLLLRELGGP +PAITRFARSLGDPVTRLDRWETELNSAEPWRITDTTSPRAIGRTYARLVLGDALNRRDRA +LLTHWLLNNTTSDNRFRAGLPRTWTIADKTGGGFYGTNNDVGIAWTEDGTPLVLAVQTTF +PDEDAPYDHALIAETAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. EN27 TaxID=211464 RepID=UPI000851E273 +------DFKKLEREFDARLGVYAIDTGTGREV-THNDRARFAYHSTFKALQAAVVLSTYS +--LDGLDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KSLDASLEKLGDDITRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPDDELIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas hydrothermalis TaxID=115561 RepID=UPI00054ACEFC +---ITAELARIEQALDARIGFAAHDLATGQRW-EVNADERFAMSSTFKTLACGALLEQVD +EGQLALDTEVSFDESALVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLILEALGGP +EAITAFARRLDDSVTRLDRFETELNEATPGDERDTTTPNAMLATLETLVLGDVLTPESRQ +QLQNWMKGNAVADGLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQAPTVAVFYLTE +TDATFEARNEAIASLGEVVQ--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ScaeMP-e83 TaxID=1758151 RepID=A0A1C4KHY2_9ACTN +---TDRAFAELERKFDARLGVYAVDTGDGRTV-THRPDERFAYASTCKALLAGAVLAKKS +--LPQMERLVRYGKEEIISNSPVTEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP +RGLQDALRGIGDQVTRCDRYEVALSDATPGDLRDTSTPRALAADLRAYALGSALPAEKRA +VLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPDAAPIALAVLSRR +DTEDAEPDDALIAGAAKVALGAf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BEE72CF +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEELSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=B9UN52_ACIBA +---VLEAVTNAETELGARIGLAAHDLETGKRW-EHKSNERFPLTSTFKTLACANVLQRVD +LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP +KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ +QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE +TDASFEERNAVIAKIGEQIAK-- +>[subseq from] Beta-lactamase n=1 Tax=Massilia sp. JS1662 TaxID=1519190 RepID=A0A098UBL0_9BURK +--AAEAAFADLERRAGGRLGVAAWRRGGTKII-EWRGGERFPFCSTAKVMVVGTVLTQAA +RTPGLLGERVRYKKTDLVSWSPVTERHVDDGMTVADLCAAALQVSDNSACNLLLDRIGGP +AAVTAFARRIGDTAFRLDRRETELNSAVPGDPRDTTTPRAMAKSLEALLLDEALAPDARR +RLLDWMLANTTGKERIQAGFSSDCRVADKTGTGAHGTTNDVGIVFPPQGQPVIVAVYYTG +STSDS----KVVADAAAIVAR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CNZ301 TaxID=2512145 RepID=A0A4Q8BM95_9ACTN +--ATTRRLKNLEREHDARLGVFAHNTRTGRTV-IHRADERFPMCSTFKPLAVAAVMKDRD +DGGRPLDERIRYSRSDLEAHSPVTGRHLAEGMTLRELCDAAIRHSDNTAANLILRELGGP +TAVTRFCRSLGDEVTRLDRWETELNSAEPGNVKDTTSPRAIGRTYMRLTLGDVLGRAGRR +QLTDWLKRNTTGDESLRAGLPEGWTVGEKTGAGEYGTHNDVGVAWTAHGEPVVLAVLTTK +KSADAEPDRALIAKTARLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Myxococcales bacterium 68-20 TaxID=1895795 RepID=A0A1M3MWT0_9DELT +--HASRELAEIEAKVGGRIGVVALDTGTGREL-AYRPDERFAMCSTFKWVLAAAVLTRVD +RAQLSLDERVRYGEADLLEYAPVTREHVEEGLTIDALAAASVIVSDNTAANLLLAKIGGP +AGFTEFVRGLGDSVTRLDRNEEMLNRNAAGDPRDTTSPRAMVGTMRKVLCGDVLSSASRD +RLLSWLRACETGKKRLRGGLPEGWIAGDKTGTGMRGAVNDVAIASPPGRAPILIAAYTSD +GNASVEVLSAAHADIGRLVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. 68-29 TaxID=1895823 RepID=A0A1M3P3X5_9GAMM +--DVEARLAALERRHGGRLGVAILDTGDGRRF-GHRADERFLMCSTHKVLAVGAVLARVD +RGEESLDRRVVFGRDVVLSWAPVTSHRVGAPMSVAELCEATITVSDNTADNLLLASLGGP +PAVTAFARRLGDTLTRLDRIEPDLNAGGNGDVRDTTTPNAMLGSLRTLMLGDALSAASRD +RLAAWMRATRTGLDKLRAGVPGDWRAGDKTGSGANGESNDVAILWPPRRKPVLVTAYCVN +PAAGATARSAVLAEVGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 007/AIA-02/001 TaxID=2509009 RepID=A0A4Y9U7T6_9BACI +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGIATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces anulatus TaxID=1892 RepID=UPI0013DB433C +----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLREHG +--LGGLERIVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQALLAELGDDVTRMERWETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAGPERA +RLTQWLTANTTGGELIRAGVPKGWTVGDKTGAGRYGTRNDIAVVWPPDAAPLVLAVLSNR +TDADADYDNTLIAKATSAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DC4ECA9 +--AADQEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADDRFAYASTWKALAAAEVLDGTT +--DAQLDRVVRYSARDLVAHSPVTEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +AGFESKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALQPADRD +VLIGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DKKDATPDDAVIAQAAEVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=A0A3R7EHM8_XANCA +--ELRYKWAEIQRGSGGRLGISLLNSDTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP +PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAGRDAALKAVAAAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Comamonadaceae bacterium ALPHA2B TaxID=2502232 RepID=UPI0010F8673C +----AAALARLEEGLSGRLGVFAIDTASGATI-GHRASERFPICSTFKAVLAGALLARSV +REPGLLDERVRYTKADLIAHSPVTGRELARGMTVAELCAATVQYSDNAAANLLLRRIGGP +EALTAQARAWGDGTLRLDRWETELNSALADDPRDTSTPEAMARLLRTLAVDDGLPTAQRA +RLQDWLRGNTTGGARIRAGMPPAWTVGDKTGTGAHGAASDIAVVWRPQAAPLVLAVYTRL +EAQDAKPRDDVIAAASRIVA--- +>[subseq from] Beta-lactamase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A5C4TQ97_ACIBZ +---VLEAVTNAETELGARIGLAVHDLETGKRW-EHKSNERFPLSSTFKTLACANVLQRVD +LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP +KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ +QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE +TDASFEERNAVIAKIGEQIAK-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora arida TaxID=2203715 RepID=A0A3N9X5N5_9ACTN +--AADQEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT +--DAQLDRVVRYPARDLVAHSPVTEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +AGFESKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALEPADHD +VLIGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLTSR +DTKDATPDDALIAQATRAVVA-- +>[subseq from] Beta-lactamase n=7 Tax=Bacteria TaxID=2 RepID=A0A127SF50_9BACT +---VLEAVTNAETELGARIGLAVHDLETGKRW-EHKSNERFPLSSTFKTLACANVLQRVD +LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP +KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ +QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE +TDASFEERNAVIAKIGEQIAK-- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter calcoaceticus subsp. anitratus TaxID=107673 RepID=Q9JP71_ACIAN +---VLEAVTNAETELGARIGLAVHDLETGKRW-EHKSNERFPLSSTFKTLACANVLQRVD +LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP +KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ +QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE +TDASFEERNAVIAKIGEQIAK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces noursei ATCC 11455 TaxID=316284 RepID=A0A1B2H383_STRNR +----AAELRDLERRYAARLGVYARNARTGQVV-AHRAQEWFAMCSTFKTVAAAAVLRDHA +-HCAPLDKVIHYPARDILPYSPKTQEHVDTGMTVGDLCAATIQYSDNAAGNLLLRQLGGP +EGLTRFFRSIGDPTSRLDRWEPDLNTAVPGDPRDTTTPEALGTSYGRLALGRALTHDARE +QLVTWLKGNTTSEHRFRAGLPQHWVVGDKTGTGDYASANDVGVAWTGRSTPIVLAVLSTK +STKDAPVDEALIADAARIVAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium loti TaxID=381 RepID=UPI00047A62B9 +---LTPKIRRLEAKSGGRLGVACRIAGTTAQF-GYRENELFPMCSTFKTLAAALILHRVE +GGIEQLDRSIKVPHNAVVASSPTTKNHAGGEMTVAQLCEAAVTVSDNGAANLLLDSFGGP +AQLTAYLRSIGDKVTRLDRIEPELNESVPSDPRDTTSPLAMIDDYERLALGDSLSQKSRA +QLVEWLVANKTGDDRIRTGLPKGWKCGDKTGTGDRGSTNDAAVIWPASGNPILMSVYLTG +TKQSLARRNAVIASVSRALVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI0005AF3E35 +---LRARWAEIQRGTGGRLGISLLNSVTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP +PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAARDAALKAVAEAVR--- +>[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium sp. NG07B TaxID=1538174 RepID=A0A2A6MCW2_9RHIZ +--DVTKLLAELEKRTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACVLARVD +RGEEKLDRRITFGKDVLLPHSPVAEKHVGGNMTVAELCDAAVTISDNAAANLMLESFGGP +AGLTSWLRSIGDGTTRLDRTEPDLNEAKFGDPCDTTTPVAMLETIGKLAFGSVLAESSRR +QLVEWMVANTTGDARLRAGLPKDWRIGDKTGTSSTGAVSDIGFAVPKGRGPILITVYTGE +AKVEPAELNPLFAEVGKIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Psychrobacter sp. DAB_AL32B TaxID=1028414 RepID=A0A229G3K8_9GAMM +---ILEAVTNAETELDARIGLAVHDLETGKRW-EHKSNERFPLSSTFKTLACANVLQRVD +LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQAALSTSDNSAANFILQAIGGP +KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSVKSRQ +QLESWLKSNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE +TDASFEERNAVIAKIGEQIAK-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. campestris TaxID=340 RepID=H9AXM3_XANCE +--MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP +PGLTRFLRGIGDTKTRSDRLEPAMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAARDAALKAVAEAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF6713D +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTARALATSLQKYVLGQALPEDKRE +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. C01 TaxID=1945856 RepID=A0A1V3PKS7_9GAMM +---AVTRLAALERKYGGRLGVSILDTGSGRRA-VHRADERFLMCSTFKLLAVASVLARVD +RGAEQLDRRIVFGKESVLAWAPVTSHRTGGQMSVAELCEAAITVSDNTAANLLLASLGGP +ATVTAYARGLGDPLTRLDRIEPELNTGGPGDVRDTTTPNAMLADLRTLLLGDALSMASRR +QLVEWLRATRTGVDKLRAGVPGDWQVGDKTGSGAHGESNDIAIIWPPQRKPLLVTAYYAA +WPADSAGHDAVLAEVGRIAA--- +>[subseq from] Beta-lactamase n=3 Tax=Xanthomonas campestris pv. campestris TaxID=340 RepID=H9AXM7_XANCE +--MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP +PGLTRFLRGIGDTKTRSDRLEPAMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAARDAALKAVAEAVR--- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. BL6 TaxID=2585770 RepID=A0A5C4Q7X5_9GAMM +---ITAELARIEQALDARIGFAAHNLATGQRW-EVNADERFAMSSTFKTLACGALLEQVD +EGQLALETEVSFEESDLVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLVLQALGGP +EAVTAFARSMDDPITRLDRYETELNEATPGDERDTTTPNAMLATLEKLVLGDVLADESRQ +QLEAWMKGNAVADGLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQPPTVAVFYITD +TEASFEERNAAIASLGEVVL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1N6PSQ1_BACCE +----NKSFTKLEKEYDAKLGIYALDTGTNQTV-VYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Polaromonas sp. 35-63-35 TaxID=1970418 RepID=A0A258NPI5_9BURK +-------WRAIESLSGGRLGVAVLQTD-G-SIeGHRLDERFPMCSTFKWLAAAHVLQRVD +RGLERLDRRIPYGREVLLPHSPVTEKHVGKGMTLGELCHATITTSDNAAGNLVLAAGGGP +QGLTTYARSLGDGVTRLDRWETELNEATPGDPRDTTSPRAMAHLLKATLLGDALSMRSRE +QLSQWLVACVTNGQRLRADLPAEWRMGSKTGGGGYGSTNDVGIFWPPGRPPILVTAYVTN +TETSQADRNAAIAAVARRVTT-- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6K431_9BACT +--EFAKRIAAIEAQTRGRIGVATVDTGSGKHL-DYRSEERFPMCSTFKFLAAAAVLKRVD +EKQEKLERFVPYDAKDILEYAPVTKTHLEEGMTLGALCGAAVAQSDNTAGNLLLYAIGGP +VGLTNFARDLGDNMTRLDRKEPELNSAGPGDERDTTTPASMLADMHQLLLENGLSASSRQ +QLEAWLRANETGSAMIRAGVPGNWIVGDKTGRGANGATNDIAIMRPPNRAPILLTIYSVG +STGSANDRTATIAEVAKIVAGEf +>[subseq from] Beta-lactamase n=1 Tax=Hydrocarboniphaga effusa AP103 TaxID=1172194 RepID=I8T4V7_9GAMM +--------RGIEDEVGGRFGVAVLDTGSGRLA-GHRLDERFPMCSTFKWVAAALVLQRVD +AGQEQLQRRIRFGREVLLSHSPVTEQHVRGDMTLAELCAATISVSDNAAGNLLLDSFGGP +AALTRYVRGLGDSVTRLDRNEPTLNESLPGDPRDTTSPRAMAGLLRTLLLGDALSAASRA +QLRRWMEATQTSDRRLRARLPAGWRLASKTGTGPRGSTNDIGVYWPPGAPPLVVAVYQTG +SAAPLSALEAAIAGVAARV---- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DC2D250 +--AADQEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT +--DAQLDRVVRYSAQDLVAHSPVTEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +AGFESKLRALGDTVTDVARYETALNEGTPGDKRDTGTARALAGDLRAYTVGVALQPADRD +VLIGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DKKDATPDDAVIAQAAEVVVA-- +>[subseq from] UPI000F044F0E UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI000F044F0E +---SDREFAKLEDKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLDGP +DGFKEALEKIGDNVTLPERFEPDLNEVNPGETHDTSTPRALAASLQKYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinoplanes brasiliensis TaxID=52695 RepID=UPI00105F307F +-----QRFGELERRFGARLGVYALDTGNGRTV-THRADERFAHASTFKALLAAVLLRRLS +--DGDLRRVIRYTRADLLEWAPITEKHVKTGMTVDALIAAAVQHSDNTAANLLLRLTGGP +EGVQRELRKIKDNTTDLSRYEPTLNTAVPGDKRDTSTPRALGADLRAFVLGDVLPAPRRQ +KLTDLLLGNTTGDTYIRAGVPSGWKVGDKTGSGGYGTRNDIAVVWPPTGSPVIIAILSDR +GRPDAPSADALIAEATRAVVT-- +>[subseq from] Beta-lactamase n=1 Tax=Alkanindiges illinoisensis TaxID=197183 RepID=A0A4Y7XFG6_9GAMM +---VNVFLSQLEKQAQGRLGLSAMNTANQMRI-DYRASERFPLCSTFKLVAVAAILQQSM +HNSILLQQHIDFTFQQVQDYAPITAQHVDRGMTVSELCAACISYSDNAAANLLLQILGGP +AALTRFARSIGDHNFRLDRWEPALNTALPQDERDTSTPAAMTDTLQRLLLGNVLAPTQRE +LLLYWLKNNTTGNARIRAGVPNSWIVGDKTGTGAYGTSNDIGIVWPTQQAPIILAIYFTC +PDKTAKPNDAIIASASKIVCQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora sp. MBT66 TaxID=1444769 RepID=UPI0007C777E1 +--ELADRFCALERSHSARLGVFAQDTVTGRTV-AYRADELFPMCSTFKTIAVAAVLRDLD +RDGTFLAQRRLYTATDVAQYAPITGLNLEAGMTVEELCAAAIRYSDNAAANLLLRELGGP +DALTRFCRSIGDRVTRLDRWEPALNSAEPGRLTDTSSPHALGRTYARLTLGQALDPADRQ +RLTGWLLTNTTGTNRLRAGLPPTWRVAEKTGTGSYGTTNDVGVTWPPDGRPIVVAVLSTK +HTADAPANEPLIAETARIVAT-- +>[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium sp. WSM3862 TaxID=632858 RepID=UPI000BAF7631 +---ATKAVEALEARNGGRLGVMVLDIGTNAAI-EYRADELFPITSTFKFLAAAGVLKAVD +DGKAKLDDRIVYAASDVEQYSPITKDHAGEGMKLEDVCAAAVVWSDNTAGNLLLRMLGGP +QGLTRFARTLGDDVTRLDRTEPTLNTAIPGDKRDTTSPRAALGDARRILLGDALSPASRK +RLEAWLIEDKVGAARIRAGLPATWGIGDKTGSGDNGTTNIVAILWPPEGAPILVAVYYTG +STAPRASREAVHRDMARIIVETf +>[subseq from] Beta-lactamase class A n=1 Tax=Rubrivivax gelatinosus TaxID=28068 RepID=A0A4R2MB92_RUBGE +------AFGAIERSVAGRLGVWAYDLETGRSL-GHRQDERFPMCSSFKWLLAAAVLARVD +RGQERLERRIVFGREALLEYAPATSHRAGGAMTLAELCEAAVTLSDNTAANLLLDTLGGP +AGLTAWVRTLGDRRTRLDRREPDLNEARPGDERDTTTPAAMVLALRQTLFGGGLSRRGAD +LLLQWMTASTTGLKRLRAGFPADWRVADKTGTGGEGTTNDVAVVWAPGRAPLLLAAYLTE +SPAAIEAREAALARVAAR----- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. PC23-8 TaxID=2012679 RepID=A0A255HG52_9BURK +--QAQAQLAALEQAAGGRLGVSALHTGSGARV-EHRADERFPMCSTFKAMLAAAVLARGS +SEPQLLDKLVRYEAKELVSYSPITEKHVATGMRVAELCAATVQYSDNSAANFLMKLLGGP +QAVTAYARSIGNQVFQLERWETELNSAIPGEVRDTTSPAATVHSLDGLLLGASLPAPQRQ +QLDIWMRGNTTGDQRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPSGDAPLVIAIYYTR +EQKNAPINQHIITKATRIVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces yokosukanensis TaxID=67386 RepID=A0A101PE04_9ACTN +--RAEAELAELERRHGARLGVYARNARTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDQT +-CRTPLDTVIHYPPRDILAHSPRTEEHVDTGMTVADLCAAAIQYSDNAAGNLLLRQIGGP +PGLTRFFRSLGDEASRLDRWEPDLNTAIPGDPRDTTTPGALGRSFERLTLGRALARADRE +RLVTWLKGNTTSGARFGAGLPRGWALADKTGTGDYGTANDIGVAWTTRGTPVLLTVLSTK +SAQDATADDALVAEAARILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00102EA35D +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEIIHYSKDDLVTYSPITEKHLETGMSLKEILEAAIRYSDNTAGNKLLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKTLATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A2X2DIQ7_PROMI +---VLEAVTNAETELGARIGLAAHDLETGRRW-EHKSNERFPLSSTFKTLACANVLQRVD +LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP +KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ +QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE +TDASFEERNAVIAKIGEQIAK-- +>[subseq from] Beta-lactamase n=2 Tax=Xanthomonas vesicatoria TaxID=56460 RepID=F0BKK8_9XANT +---LRAQWAEIERGTGGRLGISLLDSATGWRL-GQRENERFPMCSTFKFVLAAAVLQQVD +RGKLSLAQPVKIRASDMLEHAPVTKGHVGGALSVGDLCRATMIYSDNPAANLLFPLVGGP +PGVTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLHTLLLGDALQPASRT +QLTDWMIDNRTGDDCLRAGFTRDWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces fungicidicus TaxID=68203 RepID=A0A494UUV2_9ACTN +------SLTDLEREYDARLGVYALATGTGATV-VHRADERFAFCSTFKTLAASAVLDRDP +--LSRLDRRVTYTRADLVPHSPVAEKHLATGMTVRQLCDAAIRFSDNAAANLLLRDLGGP +RAVTAHLRRLGDRVSRLDQIEPELNGNPPGDPRDTTTPRAVAADYRALVLGDALPGAKRD +LLADWLVRNTTGGRRIRAGVPRDWRVGDKTGTGEWGRVNDVAVLWPPSGAPLVMAVLTDR +PGRADTTDEALVAEAARRVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Telmatospirillum sp. J64-1 TaxID=2502183 RepID=UPI00115DFC4A +--EIQALFAELESQHGGQLGVMVHNLGTGATA-CYREDERFAMCSTFKVLAAAYVMARVD +RGQESLDRRVVFSQEDIVSWSPVTEKRVGGEMTMAEICDASMTISDNTAANLQLASFGGP +SALTAYLRRLGDNVTRLDRFETELNENAPGDRRDTTTPAAMAETLRKIFFEDVLSKSSRA +QLASWFIANKTGDKRLRAGFPDTWLVGDRTGTSGNGAAHAVAIAWPTDRAPVIVTSYYNN +PSSTDEVWNAVHEEVARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=UPI001407385B +--AAQTQLAALEQAAGGRLGVAAWRQGSDLRV-AYRADERFPLASTFKAMLAGAVLARSV +SQPGLLDQHVRYEKKELVTYSPITEKHLANGMNVADLCAATLQYSDNSAANFLMTLLGGP +QAVTAFAHSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLENSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR +EQKKADTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase class A n=1 Tax=Stappia indica TaxID=538381 RepID=A0A285SQC4_9RHOB +--DIEGRLAALESKQGGRLGIAIHDVASGQTF-GNRLNERFLMASTFKLMLTAFVLARVD +REEEQLDRRIPFTKRDLVSWSPGTEKHAGGPLTVAELCEATMTLSDNTAANLLLKSFGGP +AALTGFARSLGDETTRHDRTEPALNADGPDDERDTTTPAAMAETLRKLLFGDALSRRSRD +RLTAWMVTNRTGDARLRAGFPADWLVGDKTGTSGKGHANDIGVAWPSGRGALIVTAYCEM +PKAEAKARDATMAEIARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF109F4 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKENAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=3 Tax=Salmonella enterica TaxID=28901 RepID=A0A077KT80_SALER +--QMVQQLSALEKSANGRLGVAVIDTGSGAIA-GWRMDEPFPMCSTSKVMAVAALLKQSE +QTPELMSQPQPVASGDLVNYNPITERFVGKSMTFDELSAATLQYSDNAAMNLILAKLGGP +QKVTAFARSIGDDKFRLDRNEPSLNTAIPGDLRDTSTPRAMALSLQKLALGDALGQVQRE +KLSHWLRGNTTGAASIRAGLPSGWSVGDKTGSGDYGTTNDIAVVWPTGRPPLVIVTYFTQ +PQQQAESQRPVLAKAAAIVASHy +>[subseq from] Class A beta-lactamase n=1 Tax=Gammaproteobacteria bacterium ESL0073 TaxID=2070539 RepID=A0A2Z3I9Q1_9GAMM +---TLDKIKEIESQLNARVGYVQLDFSNGLLIeGYRSQERFPMMSTFKVLLCSAVLSRVD +SGLEQLDRRVRYHQSDLIEYSPVTKEHLSEGMTVAELCNATITMSDNTAANLLLSSIGGP +KELTKFLRKVDDQTTRLDRWEPMLNESLPEDERDTTTPEAMSKTLFTLLTGKALTASSRQ +QLIDWMEADKVGGPLLRSVLPKGWFIADKTGAGEHGSRGIVAVLGPNGKPYRIVIIYLTG +SSASMDERNKQIAEIGASLIQHw +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas vesicatoria TaxID=56460 RepID=UPI00073209CA +---LRAQWAEIERGTGGRLGISLLDSATGWRL-GQRENERFPMCSTFKFVLAAAVLQQVD +RGKLSLAQPVKIRASDMLEHAPVTKGHVGGALSVGDLCRATMIYSDNPAANLLFPLIGGP +PGVTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLHTLLLGDALQPASRT +QLTDWMIDNRTGDDCLRAGFTRDWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio ascidiaceicola TaxID=285279 RepID=UPI000B8320B7 +--ELMDTVTRLESEVGGRIGVVLQHTGSEWGI-EHREDERFPLASTFKALLCGAVLSRVD +RGEESLDDLVTYKATELVSYSPVTKNHVASGMSVGQLCEATVTMSDNTAANLLLKRVDGP +EGLTRFLRGLGDRVTRLDRNEPALNEAKHGDSRDTTTPSAVLKTLDRLLFEDVLLPSSRA +QLQQWMVDDKVADELIRKHLPKGWRIADKSGGGQNGSRGIISVIWPDTGAPYLAAVYMMG +SDASFKQRNAVIAEIGKAMIE-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis coloradensis TaxID=76021 RepID=A0A1R0KNA3_9PSEU +--QFHDRLMELEKKFDARLGVYALDTEGGGTV-EHRADERFAFCSTFKGVAAAAVLHRNP +--LSHLETRVRYSRDELMKHAPITGQHVSTGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +AELTAFARGLGDTVTQMDRLEPAITEATPGDPRDTTTPRAFGTDYRKIVLGDALPDDKRD +FLRDLLQRNTTGAERIRAGLPSGWTVADKTGTGEHGTLNDIAVVWPPDKAPIVVAIMSSK +AAKDAPYDQALLAEAAKYVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=A0A5D4RU48_9BACI +--DLDETFATIESDYDARVGVYAIDTGSDQTI-AYRSEERFAFASTYKALAAALVLKQNT +--MEELEEVIAYTEDDLVSYSPITEKHVDTGMTLAELSEAAVRTSDNTAGNLLFEELGGP +EQFQQSLREIGDEVTQSDRYETALNEFTPGNTRDTSTPAALATSLQGFAVGGLLPDDKRE +ILIDWMKGNATGDTLIRAGAPDGWTVADKSGAGRYGTINDIAVVWAPDREPIIMAIMTRH +DTEDADYDDALIAEVAEVTLE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZHX6_KLEOX +-dTLQKKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP +EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAK----------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NP10 TaxID=1141731 RepID=A0A433DWS8_9ACTN +------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTMKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPDLSRWVPGEKRDTSTPRALAEDLRAFVLGKALHPPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces achromogenes TaxID=67255 RepID=UPI00099D4A8A +-----AELAELERRYGARLGVYARNVRTGRTV-AHRAGERFAMCSTFKAFAAAAVLRDHG +-DRAPLDRVVHYPPRDILPNSPRTQENLETGMTVAGLCAAAIQYSDNAAGNLLLRELGGP +AGLTRFLRSLGDTVSRLDRWEPELNTAIPGDVRDTTTPEAIAGSLERLTLGRALRRADRQ +RFTGWLKGNTTSEERFRKGLPPAWVVADKTGTGDYATANDIGVAWTTRGTPVVLAVLSDK +SAKDAPVDQALIAEAAAVVAR-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q5MDA3_ECOLX +-----EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDQQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQI----------- +>[subseq from] class A beta-lactamase n=1 Tax=Ensifer sp. Root142 TaxID=1736461 RepID=UPI00070FA2C4 +---VDTRLAELEKRTGGRLGVSVLDMETNVSF-GRRESERFAMCSSFKTLAAGFALARAD +QGAEKLDRRIVVAQKEIVAHSPVTEKHVGGEMTIAELCAATLTTSDNAAANLLLENFGGP +PALTAWLRTIGDETTRLDRNEPALNEAKVGDPRDTTTPAAMLETLGNLAFGPVLAEASRK +LLIEWMVANTTGDLRIRAGLPKAWKVGDKTGTNGNGAASDIAIVWPEGRGPLLIAVYIAE +ATAPLAELNTVFADVGRMAAE-- +>[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DD3F104 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYXDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSXPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAXPADWAVGDKTGTCGYGXANDYAXVWPTGRAPIVLAVYTRA +PNKDDKYSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. 15K316 TaxID=2530376 RepID=A0A4R4QLR1_9ACTN +--AVDREFGRLETEFGARLGVFAVDTGSGATV-RHRADERFAYASTFKALAAAVLLDRTS +--AAELDEVVRYSRSDLVAHSPVTEQHVATGMRLRDVADAAVRYSDNTAANLMLRRLGGP +DGFERELRRLGDTTTEADRYETALNEGRPGDRRDTSTPRAFATDLRAYTVGDALSREDRD +ILNGWLRGNTTGDALIRAGVPAGWTVGDKTGGGGYGTRNDIAVLRPPAGAPIVLAVMSSR +DAENAPYDDALIARATRIVVD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Thauera sp. K11 TaxID=2005884 RepID=A0A290ZUV5_9RHOO +--AVAARLQALEADVGGRLGVYVVDTQSGAGY-GYRPDERFLMLSSFKLLASALVLHRVD +AGLDSLARRISYGREDLVPWSPVTGRHAGGEMTLAGLCEAAVTTSDNTAANLILASYGGP +AALTAYLRQLGDTVTRLDRNEPTLNDKHPHEPFDTTSPRAMVGSMRKLVLGEALSAASRE +RLQQWLLGNTTGGRRLKAGLPADWRIGDKTGTAGM-DANDVGVVWPPGRAPLLVAAYLAD +SPAEGAAREAAIADVGRLL---- +>[subseq from] Beta-lactamase n=1 Tax=Phyllobacterium phragmitis TaxID=2670329 RepID=A0A2S9IK71_9RHIZ +-qNLGSRLAELEGRHGGRIGVAVLNLATGERI-GHRSDERFLMCSTFKALAAAFILARVD +RGEEQLGRRIVYSKKDLVTWSPITENHVGGALSVAELCQATVTLSDNTAANLLLASFGGP +AALTTFLRSIGDEITRLDRTEPELNQDKPGDLRDTTTPAAMLGTLRKLVFGDVLSRPSRA +QLAAWMIMNKTGDAKLRAGFPGNWTVGDKTGGNGFGNSNDIAIAWSPDRGAVIVAAYCEI +PSVSEEERGAVLAEVGRIAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB4996 +--EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD +KGEENLERRVVYEKEQLIAYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLILESLGGP +KELTNWLRTLGDGSTRLDRIEPDLNDIAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK +TLIEWMVANTTGNERLRTGLPETWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTN +ATVATAEINPVFGEVGRIVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces anulatus TaxID=1892 RepID=UPI0013C9410E +----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLREHG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQALLAELGDDVTRMERWETELNEWTPGATRDTSTPRALAEDLRTFVLGNALAGPERA +RLTQWLTANTTGGELIRAGVPKGWTVGDKTGAGRYGTRNDIAVVWPPDAAPLVLAVLSNR +TDADADYDNTLIAKATSAAV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NBRC 110611 TaxID=1621259 RepID=A0A1B6ABE5_9ACTN +------EFKKLERKFDARLGVYAIDTGTGREV-AYNDGERFGHHSTFKAFAAGAVLRKHS +--LGGMDKVIKYSSDDLVDNSPITEKHVATGMTLRELCDAAVRYSDNTAANLLFADLGGP +KALNAVLKELGDDVTRMARIEPELSNWVPGEKRDTSTPRALAEDLRAFVLGDALGKAERE +QLTQWLRTNTTGAELIKAGVPKNWVVGDKTGAGSYGARNDIAVVWPPDGAPIVMAILTNR +TTKDAVFDNKLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces globisporus TaxID=1908 RepID=A0A423UYI7_STRGL +------DFKELERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A2L1J0V2_PSEAI +------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATM------------------ +>[subseq from] Beta-lactamase n=2 Tax=Acinetobacter TaxID=469 RepID=J3S801_ACIBA +---VLEAVTNAETELGARIGLAVHDLETGKRW-EHKSNERFPLSSTFKTLACANVLQRVD +LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP +KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ +QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE +TDASFEERNAVIAKIGEQIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. UNC358MFTsu5.1 TaxID=1449049 RepID=UPI0005555552 +-----RGIAALEARSHGRLGVSVLDSASGKTF-AYRGDERFAMCSTFKALVAGLILKRVD +QGQERLDRRIPYGREVLLAHSPATEKHVGQGMTVGALCEATVTLSDNAAANLLLMSFGGP +PALTTFVRGLGDKVTRLDEYEPTLNVVRPGEIHDTTSPNAMLATLRALTLGPVLSPASRR +QLVDWLVANQTGDARLRAGLPKGWKVGDKTGSWGVGTTNDIAVVWPPGKPPLLITAYLSR +STLDNDGRNAVIAEVARLVTT-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI00094B1415 +--ELRYKWAEIQRGSGGRLGISLLNSDTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP +PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALRPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAGRDAALKAVAEAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI0007F93709 +-eKLNHELTILEKNSGGRLGVALINTENNDLT-LYRADERFAMCSTSKVVAVSALLKKSE +SDKTILGKNIALHEAELVTWSPVTEKNITTGMTLGALSAATLQYSDNTAMNSILNYLGGP +SAVTAFARSIGDEKFRQDRPEPELNTAIPGDERDTSTPLAMATTLQKLTLGDALATPQRK +QLVEWLKGNTTGTASIKAGLPEGWIVGDKTGSGDYGTTNDIAVIWPPEKSPLILVIFFTQ +PLQDAQSRKDILAEATKIVVSPf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. Root239 TaxID=1736499 RepID=A0A0Q9HGT1_9BACI +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQSLPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. URHA0033 TaxID=1298862 RepID=UPI000407770B +-----RGMAALEARSGGRLGVAVLDTASGKTF-AHRGDERFAMCSTFKALVAGLVLKRVD +QGLERLDRRIVYGRNVLVAHSPVTEKHVDEGMTVGALCEATVTLSDNAAANVLLYTFGGP +PALTAFLRGLGDKVTRLDGYEPGLNIVRPGEIHDTTSPAAMLATLRALTLGPALSPASRQ +QLVAWLVANQTGDKRLRAGLPGGWTVGDKTGSWGAGTTNDIAVIWPAGGPPLLIAAYLSR +STLSDDGRNAVIAEVARLVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus ihbetae TaxID=1870820 RepID=UPI000985D929 +------LFKSLENEYDARLGVYAIDTGSGETI-AYRADERFAYTSTFKALASGAVLLQNS +--IEEIDEVISYSAEDLVTYSPITEKHVSTGMTLRDIMDAAIRYSDNTAGNLLLEQLGGP +EGFEAALRQIGDTVTQADRYETELNEAVPGDDRDTSTARALATSLNAFALGDVLPKDKQT +ILTDMLRGNTTGDELIRAAVPEGWAVGDKTGAGSYGTRNDLAIVWPPEGDPVVLAVLSSR +DTQDAEYDNALIAKAAEAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000DEF32B7 +----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWXVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID6648 TaxID=2706084 RepID=A0A6B3CJG2_9ACTN +------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGLDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEQRDTSTPRALAGDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI0005C463FB +--ELRYKWAEIERGSGGRLGIGLLNSDTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP +PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAARDVALKAVAEAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Sediminibacillus terrae TaxID=1562106 RepID=UPI001296E437 +--DLDEAFTEIEEAFDARLGVYAIDTGTNQSV-EYNPDERFAYSSTYKLLAAAFVLKQND +--LQDLEEVVTYSKDDLVTYSPVTEKQVDTGMTLSEISEAAIRESDNTAGNLLLDALGGP +DNYKQALRDIGDDVTQPERYETELNAFSPENKRDTSTPRAMANNLRKVALGDFLPKEKQE +LLIDWMKGNATGDALIRAGKPEGWTVGDKSGAGSYGTRNDIAIVWPPGREPIVMAIMSRH +KTEGAEYDDELVAKAAEATLNAf +>[subseq from] class A beta-lactamase n=1 Tax=Xenophilus sp. L33 TaxID=1747220 RepID=UPI00131BDF9E +--SLGRAFADIEQMSGGRLGICVLDTGSGLRA-GHRQDERFPLCSTFKLLAAAAVLARVD +KGQLRLDQRIVYGAGDLVAGSPETKLHVGEGMPLAAVCKAAITLSDNTGGNLMLAQIGGP +AGLTRFARTLGDGLTRLDRTETTLNEARPGDPRDTTTPQAMLGDMHRLLLGSALSVGSRQ +QLLEWLEANKTGDKRLRAGLPADWRVGDKTGSGENGTANVIAIVRPPQRAPILVTAYLTA +TTASTDLQNASLAAVGAAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A120EEM8_BACMY +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGEP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas albilineans TaxID=29447 RepID=UPI0005F30977 +--ALQQRLAEIERRSGGRLGVYLLDSGTGQRI-GRREQERFPLCSTFKFVLVAAVLQRVD +RGEIGLDQRVRVRAADVVSYAPVTKPHVGGTLSVDALCRAAMIFSDGGAANLLLRLVGDP +PGLTRFLRAHGDTQTRSDRNEPSMNAFALDDPRDTTTPAAMASTMRTLLLGDVLQPASRQ +RLIDWMIDNRTGDDCLRAGLPAGWRIGDKTGNNGTDSRNDIAIVWPPGRAPLLLTAYLNM +ATVDSDARDAALKAVAQAVVAWw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000D1102D2 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKESLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDILSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis DB27 TaxID=1431339 RepID=W8Z1P0_BACTU +-----DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADTSLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGGEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A345N8B5_ACIBA +---VLEAVTNAETELGARIGLAAHDLETGKRW-EHKSNERFPLSSTFKTLACANVLQRVD +LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP +KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ +QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE +TDASFEERNAVIAKIGEQIAK-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. DMKU_BBB3-04 TaxID=2593654 RepID=A0A553GTZ8_9PSED +--DLEARLIALEGETGGRLGVAVLDASGGLRA-GHRQDERFPLCSTFKVLLAAQVLARCD +QGVEDLERPVRVRADDLLDYAPVTRPAVGRELSVATLCEAAITLSDNTAANLLLARSGGP +AGLTAFLRSLGDKVTRLDRIEPDLNEARPGDPRDTTSPAAMLHSLQRLLLGDALAPASRD +RLEAWMVATRTGDARLRARLPADWRAGDKTGTGARGTYNDVALFRPPQGGPWLVSAYLTG +ASAPAARCEAALAEVGALIA--- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella TaxID=570 RepID=Q6ZY54_KLEPN +-----EQIKQSESQLPGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTHLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD +TPASMAERNQHIA---------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZHY6_KLEOX +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGEVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAK----------------- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. Q54 TaxID=1335060 RepID=UPI00115A2788 +--TVAETAAEVEADLGGRVGVLLQQYGEAPAA-TYRADERFPLASTFKALACGAALSRVD +AGEQDLEAIIKYGADDIVTYSPITEKHVGVGMTLGDLCHATITLSDNTAGNLVLDSVGGP +SGFTAFMREIGDEVTRLDRWEPELNEALPDDPRDTTTPRAVVTTLERLLLGDVLLPASRR +QLEEWMIADQVADKLIRASLPKGWTIGDKTGAGERGSRSIIAIIRPPQGKPWLAGIYLTG +SDADMDKRNEAVATVGAAIVR-- +>[subseq from] Beta-lactamase n=1 Tax=Mycetocola sp. 622 TaxID=2173166 RepID=A0A2U1TCB2_9MICO +----DGEFGELEQKFDARLGVYALDTGTGLAL-EYRSDERFAYASTIKVFASAVLLDQTS +--DDELDARVTYDESDLLDYAPITEQHVDSGMTLRELGDAAVRYSDNTAANLIFERIGGP +EGLADALTAMGDDVTQVDRTEPELNEATPGDPRDTTTAEAFATTLEALVLGDALEASDRE +LLTEWLVGNTTGDKLIRAGVPADWTVGDKTGSAGYGTRNDVAVIWPTEGDPIVLTVLSSR +SEADADYDDALIAESTAVAIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000A30309B +----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSITNPERFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGNNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH +AKEDAKYEDKLIADASKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000779F760 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMEDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +GKEDAEYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Verrucosispora sp. FIM060022 TaxID=1479020 RepID=A0A432N762_9ACTN +-------FGPLEQEFDARLGVYAVDTGTGRTI-EHRADERFAYASTFKALAAAAVLRATT +--AEELDQVVRYSRDDLVTYSPITEQHVATGMTLRAIADAAVRYSDNTAGNLLFDRLGGP +AGFKQALRDIGDDVTEPARIETALNAATPGDVRDTSTPRALATSLRAYAVDDALTTEDRD +VLVDWLKRNTTGEKVIRAGTPDGWVVGDKTGSGGYGTRNDIAVIWPPDREPIVLAVLSSR +DAEDAGTDDALLARAAELTL--- +>[subseq from] Beta-lactamase n=1 Tax=Psychrobacter fozii TaxID=198480 RepID=A0A2V4VSZ5_9GAMM +---ILEAVTNAETELGARIGLAAHDLETGKRW-EHKSNERFPLSSTFKTLACANVLQRVD +LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP +KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ +QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE +TDASFEERNAVIAKIGEQIAK-- +>[subseq from] Beta-lactamase n=1 Tax=Phaeobacter piscinae TaxID=1580596 RepID=A0A291FV89_9RHOB +-qDLQNTVADWEERLNARIGVVLRDTSSDWEI-SMRAEERFPMSSTFKSLLCGAVLSRVD +AGQEDLDRRVTYAEGDLVAYSPVTEQHLDNGLTVGELCEATVTLSDNTAGNLLLDTVGGP +EGLTNFLRDIGDQTTRLDRWETALNEAAPGDPRDTSTPSAILNTLETLLLGDVLEPATAA +QLRQWMIDDQVADALIRAHLPEGWVIGDKTGAGGNGSRAIIAFIEPEADVHYFAAIYLTE +SDADFALRNQVVSEIGQAMI--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MNU77 TaxID=1573406 RepID=A0A1Q8U065_9ACTN +----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLREHG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQALLAELGDDVTRMERWETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAGPERA +RLAQWLTANTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +TDPDADYDNTLIAKATSAAVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces olivochromogenes TaxID=1963 RepID=UPI0007497376 +hrDTRARLRELEARHGARIGAFAYNLRTKATV-RHRAAERFPGCSVFKTLAAAAVLRDLD +RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPTTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PAQDAAADSPLVAATATVLA--- +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Enterobacterales TaxID=91347 RepID=Q48488_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATM------------------ +>[subseq from] Beta-lactamase n=1 Tax=Bacillus tequilensis TaxID=227866 RepID=A0A2X0X2U6_9BACI +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-SYRPHERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLDGP +KGFEKSLKQIGDHVTRANRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTIDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKTVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. 60-20 TaxID=1895819 RepID=A0A1M3PR76_9RHIZ +--DVDKQLADLEKRTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD +QGVEKLDRRVTYGKDKVVTYSPATEKHADADMTIAELCGAAITLSDNTAGNLLLDSFGGP +AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAILDTIGLLTLGNTLSETSRD +QFVNWLVANTTGNNRLRAGLPNEWKVGDKTGTGNNGSYADIAVIWPPERGAILVTTFVAE +ATAPAKDVESVFAEVSKIVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0011B7D079 +----DGEFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPENKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. STM 3809 TaxID=551936 RepID=H0T420_9BRAD +--DLQATIAGIETDSGGRLGVALLDTASGALS-GHRLDERFPMCSTFKALLAAAILAKVD +AGAEQLSRRLPITQADILAYAPVTKLHVSTSLAIGELCEAAVTLSDNTAANLLLATLDGP +AGLTRAIRGFGDAITRLDRIEPALNESVPDDPRDTTTPAAMARTLAKLTTGNALSASSRD +VLNGWLLGCKTGAAKLRAGLPASWRVGDKTGSGERGSSNDVAVIWPAGRAPVIVTSYLTE +TKASDDKRNAAHAAVGRAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces anulatus TaxID=1892 RepID=UPI0013BDDE91 +----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLREHG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAELGDDVTRMERWETELNEWTPGATRDTSTPRALTEDLRAFVLGDALAGPERA +RLTQWLTANTTGGELIRAGVPKGWTVGDKTGAGRYGTRNDIAVVWPPDAAPLVLAVLSNR +TDADADYDNTLIAKATSAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000E0DDC30 +---SDREFAKLEDKYDANLGVFALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDNVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPKDKRE +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F931_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDECDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIVALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase (Penicillinase) n=1 Tax=Xenorhabdus bovienii str. kraussei Becker Underwood TaxID=1398204 RepID=A0A077PTY1_XENBV +-nQITNQLSALEKNANGRLGVVLIDTADHSII-TYRGHERFPLCSTSKMMAVSALLKKSE +TDKDLLNQRIHYQQSDIVEYSPITEKHLKDGMTLAELSAATIQYSDNTAMNLLLGQLGGA +HSVTRFARSIGDNTFRLDRKEPELNMVTPGDERDTTTPQAMADSLYKLALGNTLAATQRA +YLVEWLKGNTTGGTSIRAGVPDNWIVGDKTGRCDYGSTNDIAVIWPDDKAPLILVTYFTQ +PSKDAKAHNDVLAAAARIMTQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas sp. C22 TaxID=2580567 RepID=UPI0011A1396C +---ITAELARIEQALDARIGFAAHDLATGQRW-EVNADERFAMSSTFKTLACGALLEQVD +EGQLALDTEVSFDESALVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLILEALGGP +GAITAFARRLDDSVTRLDRFETELNEATPGDERDTTTPNAMLATLETLVLGDVLTPESRQ +QLQDWMKGNAVADGLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQAPTVAVFYLTE +TDATFEARNEAIASLGEVVQ--- +>[subseq from] Beta-lactamase n=1 Tax=Azoarcus sp. DD4 TaxID=2027405 RepID=A0A4Y6KQG6_9RHOO +--QLAELCRKLEADSFGRLGMYLFDGRSGQEF-LYRSEERFPMCSTFKWLAAAAVLARVD +AGKERLDRRIRFAGQDLLEYSPVTRSFADGPMSVAQLCEAAVADSDNTAANLLLDALGGL +EAFNAFLRAQGDSLTRLDRYEPDLNEARPGDPRDTTTPAAMGADLRRLLLGDGLGSHSRQ +QLTDWMLATRTSGERLRAGLEAGWRLADKTGTGDNGTANDVGVYWTPTGQPVVLCVFLTG +ARTDRAAQAAVMASLGRQV---- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2A7C568_BACCE +----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITKKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKKDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD57882 +--EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD +KGEENLERRVVYEKEQLIAYSPETEKHVGGEMSVGDLCKAAITLSDNTAANLILESLGGP +KELTNWLRTLGDGSTRLDRIEPDLNDIAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK +TLIEWLVANTTGNERLRTGLPEAWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTN +ATVTTAEINPVFGEVGRIVAE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0009BE7069 +-qATHKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS +--TDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVCPQNRAPIIIAILSSK +DEKEATYDNQLIAEATEVIVK-- +>[subseq from] Beta-lactamase n=3 Tax=Xanthomonas vasicola TaxID=56459 RepID=A0A2P5ZK72_XANVA +--MLRAQWAKIERGTGGRLGISLLDSATGWHL-GQRQDERFPMCSTFKFVLAAAVLQRVD +QGKLMLAQRVKIRASDMLEHAPVTERHIGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRSIGDAQTCSDRHEPEMNRFAAGDPRDTTTPAAMANTLRTLLLGDALRPASRK +QLTDWMINNRTGDDCLRAGLTRDWKIGDKTGSNGIDTRNDIAILWPPKGAPLLLTAYLNG +AKVDDAARDAALKAVAVAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E325B6C +--MLRARWAEIQRGTGGRLGTCLLDSGTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP +PGLTRFLRGIGDTKTRSDRIEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLAAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAGRDAALKAVAEAVR--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0H4J428_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMA----------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2E6_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPSQAPLIAAIYLTQ +SDASMEQRNAAIAAIGTALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0R7FFW3_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +ES--------------------- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B1B99E +-qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRYSDNTAGNILFHKIGGP +KGCGGGLRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTIGNALPHQKRN +ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEKEATYDNQLIKEAAEVVID-- +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T131_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLDALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEALSPAAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLIAAIYLTQ +SDASMEQRNAAIAAIGTALAE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T0V2_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLDALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEALSPAAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLIAAIYLTQ +SDASMEQRNAAIAAIGTALAE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus sp. FJAT-21352 TaxID=1581030 RepID=A0A5E8LAC3_9BACI +---TIKKFEQLEKEYDARLGVYAIDTGTKETV-EFHENERFAFTSTHKALAVGALLQQKS +--IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP +AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGNPIVLAVLSSR +DEKEADYNDELIAEATEEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. MSP13 TaxID=1071061 RepID=UPI0009E20162 +----NEKFVQLEKKFDAKLGVYAINTGTNKTI-SYRPNERFAYASTYKVLAAAAVLKKNA +--IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEIAEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNNLTPDKRT +ILTDWMRGNATGDELIRAGAPIGWLVGDKSGAGSYGTRNDIAIVWPPHRAPIVVAILSNR +FTEDAHYDNALIAEAAKVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000B8297AD +---TDRAFAELERKFDARLGVYAVDTGDGRTV-THRPDERFAYASTCKALLAGAVLAKKS +--LPQMERLVRYGKEEIISNSPVTEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP +RGLQDALRGIGDQVTRCDRYEVALSDATPGDLRDTSTPRALAADLRAYALGSALPAEKRA +VLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPDAAPIALAVLSRR +DTEDAEPDDALIAGAAKVALGAf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID8374 TaxID=2690354 RepID=UPI0013684D21 +---TDRAFAELERKFDARLGVYAVDTGDGRTV-THRPDERFAYASTCKALLAGAVLAKKS +--LPQMERLVRYGKEEIISNSPVTEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP +RGLQDALRGIGDQVTRCDRYEVALSDATPGDLRDTSTPRALAADLRAYALGSALPAEKRA +VLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPDAAPIALAVLSRR +DTEDAEPDDALIAGAAKVALGAf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. SPB7 TaxID=2715209 RepID=UPI0014201ADF +----SKKFVQLEKKFDARLGVYAIDTGTNKTI-TYRPNERFAYASTYKVLAAAAVLKKNP +--IDKLNEVIHYSKDDLVTYSPITEKHVDKGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFIVDNTLTSDKRT +ILTGWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDASYDNALIAEAAKIVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Verrucosispora maris TaxID=1003110 RepID=UPI0005BCF2E2 +-------FGPLEQEFDARLGVYAVDTGTGRTI-EHRADERFAYASTFKALAAAAVLKATT +--AEELDQVVRYSRDDLVTYSPITEQHVATGMTLRAIADAAVRYSDNTAGNLLFDRLGGP +AGFKQALRDIGDDVTEPARIETALNAATPGDVRDTSTPRALATSLRAYAVDDALPTEDRD +VLVDWLKRNTTGEKVIRAGTPDGWVVGDKTGSGGYGTRNDIAVIWPPDREPIVLAVLSSR +DAEDAGTDDALLARAAELTL--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. PgraA7 TaxID=1157641 RepID=A0A212RVT0_9ACTN +------DFKKLERAFDARLGVYAIDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +GGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAVIRAGVPENWTVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas citri TaxID=346 RepID=UPI00052D5C41 +--MLRAQWAQIEHGTGGRLGICLLDSATGKRL-GQREHERSPMCSTFKFVLAAAVLQQVD +QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. cf386 TaxID=1761904 RepID=A0A1H0N9F8_9ACTN +--DVTARLRALEQQHGARLGVFAHNLATKRTV-RHRADERFPICSLFKTLAAAAVLRDLD +RDGEVLNKRIHYTAADVVANSTVTEKHVATGMTVAELADAAIRFSDNTAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRATDTTSPRAIGRTYARLVLGNALNRPDRD +LLTHWLLNNTTSVNRFRAGLPRTWSIADKTGGGSYGTNNDAGIAWTEDGTPLVLVVQTTR +PDQDAAPDHALIVETAELLAD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacter asburiae TaxID=61645 RepID=H1AFJ1_ENTAS +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVRELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVILSCG +IRASMAERNQQIA---------- +>[subseq from] Beta-lactamase class A n=1 Tax=Pleomorphomonas sp. CF100 TaxID=2135722 RepID=A0A4R8F802_9RHIZ +-------FAQLEKERGGRLGVAALDKTTGSRI-GYRADERFAMCSTFKCLAAAAALARVD +KGELKLDKVISFGKADLLSYAPVTKQHVDKGMTLEELCAAAVSVSDNTAANLILKEIGGP +AGWTAYARSLGDKVSRLDRTEPALNTAVAGDVRDTTSPNAMLGNLDKLFIGDILSETSRD +KLEEWMVTGTVTGPLIRAGVPKNWQVADKSGSGANATRNDIGVLYRPEKAPIIAAIYYTG +SKLDMDGQNKVIADAAALIASRf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A8HNS6_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAP--------- +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Micromonospora sp. CNZ299 TaxID=2035244 RepID=A0A2G6XJX6_9ACTN +--AAEQEFQRLEKTFQARLGIYAVDTGTGRTV-EHRPDERFAYASTWKALAAAEVLDGTT +--DAELDRVVRYSAQDLVSHAPITEKHVAEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +QGFEKKLRGIGDTVTDPARYETALNEATPGDRRDTSTARALAGDLRAYTVGDALTPADRD +VLLGWLKGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVVAVLSSR +DKLDATPDDALIAQATTVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL6665CI2N2 TaxID=1938806 RepID=A0A4R8JTS0_9BURK +--AIRRRLVEIEAASGGRLGVSIVDTMSGLHA-GLRTDERFPMCSTFKMLVAGAVLARTD +RGEEDLQRRVVFSQSDVVSNSPATSKHTRELMSIAELCKAAITLSDNTAANLLLATFGGP +AGLTAFARSLGDGVTRLDRIEPMLNEGTPGDLRDTTTPNAMLGNLRELLLGERLSSSSRA +QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDIAILWPSGRGPVLVTVYLTE +TDGNAARSNAAIADVGALVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia araoensis TaxID=228600 RepID=UPI000307F065 +-----AGVADLEARYGAQIGLFALDTGTGRTV-THRADERFPFLSTFKTLAVAAVLRAHP +LDTGYFDQVLRFHEADLVDNSPVTSAEVAGGMTLARVAEAAITRSDNTAGNLLLREIGGP +EGLTAFLRTLGDPTSRLDRWETDLNTAIPGDERDTTTAAALAADYRALALGDALGARERD +QLVAWLKANTTGGKRIRAGLPADWVTGDKTGTGSYGSANDVAIVWPEGGAPIVIAILSRK +PAADAEVNNDLLAEVTKVAVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Hydrogenophaga sp. 2FB TaxID=2502187 RepID=UPI0010F4E572 +---LQDSLRDIEKQAKGRLGVHIIDTASGREL-GWRGDERFLMLSSFKLLASALVLDRAD +RGEASLEQRIRYRKQDLVSWSPVTERHVGGELSLAQLCEATITTSDNTAANLILASYGGP +AALTAYARRLGDRATRLDRTEPELNRAASGEPLDTTTPRAMAHTLNKLLLGDALKPASRE +RLTQWLRANTTGGKRLRAGVPSGWQIGEKTGTAGD-DANDIGIAFPPQRKPIIVTAYLAE +SVTDSGTREAALASVGRLLAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E1EB0BB +--ELRYKWAEIQRGSGGRLGISLLNSDTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP +PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATIDAAGRDAALKAVAEAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Nevskia ramosa TaxID=64002 RepID=UPI0003B2F4D0 +---LQARCKALEAKLGGRLGMNCLEVGSGRMV-GYKADERFPMCSSFKWLAAAVVLSRVD +AGQEQLGRRIQFSRDELMEWSPVTEPRLGGDMTLGELCEAAITESDNTAANLILRETGGI +PEWNRYMRSIGDAYSRLDRGEPLLNEALPGDVRDTSTPAAMTANLRRLLLEDQLSPASRE +QLTQWMLATKTSDKRLRAGLPAGWRLADKTGTGDTGTAGDVGVLWSPSGKPIIIAVYLTR +ARVSRAEQEAAIAEIGRWVR--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. campestris TaxID=340 RepID=H9AXM5_XANCE +--MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP +PGLTRFLRGIGDTKTRSDRLEPAMNGFAPGEPRDTTTPAAMAATLRTLLLGDALHPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAARDAALKAVAEAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000E1F9825 +---LRAQWAEIERGTGGRLGISLLDSATGWRI-GQRENERFPMCSTFKFVLAAAVLQQVD +RGKLPLAQPVKIGASDMLSHAPVTERHVGGALSVGELCRATMIYSDNPAANLLFPLVGGP +PGVTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLGTLLLGNALQPASRK +QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAGRDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces albireticuli TaxID=1940 RepID=A0A2A2DEQ2_9ACTN +--EAERAFGELERTYDARLGVYAVDTGSGRVV-AHRPDERFAYASVCKAFLAGAVLKKNT +--LQGLDRHVRYGREVPVGHSPVTGRHVGSGMTLRELCDAAVRYSDNGAANLLFDELGGP +KGLQEALAAIGDRVTRADRYETDLSEAAPGDPRDTSTPRAMAADLRAFVLGDALAPDERS +ALTDWLKRNNTGDKLIRAGVPAGWQVGDKTGSGGYGARNDIAVLWPPRAAPIVVAVFSSR +TAKDAKADDTLIAKATEVTVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0H4IQA0_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TP--------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SVW4_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGELLSPAAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPSQAPLLAAIYLTQ +SDASMEQRNAAIAAIGTALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NBRC 110027 TaxID=1546107 RepID=A0A0P4RF40_9ACTN +---SAQAFKELERKFDARLGVYAINTSTGREI-TYHQDERFAHASTFKALAAGAVLRKYS +--LPGMDKVITYSRDDLVSNSPITEKHVDTGMTLRALCDAAVRYSDNTAANLLLDSIGGP +KGLDAALEKLGDHTTRMVRHEPELNDWAPNDTRDTTTPRAFAKDLRTFVLGDTLPRRERA +QLAKWLQTNTTGAKLIKAGMPKTWLVGDKTGAGSYGTRNDIAVVWPPHAAPIVVAIMSNR +TQKDAKYDDALVAGAASVVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. IC_126 TaxID=2547400 RepID=A0A4R0PSG2_9PSED +-----RKVMELETRLGARIGAVVRSSHADMHW-AYRADERFPMCSTFKLLASGSLLAQVD +AGREQLDRIVRFEIADVVDYSPITESQAGGDMTLAQLCEAALTHSDNTAGNLILEQIGGP +GGVTEFAWSLGDTVTRLDRWETELNEATPGDPRDTTTPAAMAQCVDVMLFGDALSASSQQ +QLSDWLVANKTGDAKLRAGMPASWRIGDKTGGGDHGTMNDVAVIWPPQQHPLIVSIYMTE +TVASFDDRNAAFAELGRTLYELf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium (strain DSM 319) TaxID=592022 RepID=D5DH82_BACMD +---SDREFAKLEDKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLDGP +DGFKEALEKIGDNVTLPERFEPDLNEVNPGETHDTSTPRALAASLQKYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. A1136 TaxID=2563102 RepID=A0A4S2ST97_9ACTN +--SAADAFAALERGHDARLGVYAVDTGTGRTV-AHRADERFAYASTYKALAAGAVLRKNT +--LEGLEKVVHYTHGDLVTYSPVTEQHVDTGMTLRALCDAAIRYSDNTAGNLLLDALGGP +KGFQAALVALGDGTTQVDRYETALNEATPGDPRDTSTPRTLAADLRAYTLGDALNAEKRA +LLTGWLGRNTTGDELIRAGVPAGWWVGDKTGSADYGTRNDIAVVRPPEAAPIILAILSTH +ASRDTTPDNELIAQATRDVI--- +>[subseq from] Beta-lactamase n=2 Tax=Baia soyae TaxID=1544746 RepID=A0A4R2S3T1_9BACL +---VNQTFTDLEKKFDARLGVYAIDTGTGRSV-THRSDERFAYASTFKTLIVGMLLKQKS +--VDQLNELITYTKEDVTRYAPITEKHIDTGMTLKELCDATLRYSDNAALNLILEKIGGP +TVARKELMRIGDYTTKPFRFEPELNEATPGDIRDTSTPKALATSLKAFTLGNVLQADKRD +MLIDWMKRNTTGDKLIRAGVPAGWVVGDKTGSGGYGTRNDIAIVWPPNRAPIVIAVLSSR +DKKDATYNEELIAQATKEVIR-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T1Q6_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEVLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSIVAILWPPGQAPLLAAIYLTQ +SDASMEQRNAAIAAIGTALAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. SYP-A9097 TaxID=2663237 RepID=UPI00129B5CDA +-----QPFADLETKAGGRLGVYAIDTATGKTV-TYRDGERFPIASTFKGLACGALLRGHP +LSSGYFDQVIHYPASDLVTYSPETEKHVDSGMTVTELCRAAITLSDNTAGNQLLKLLGGP +EGLTAVIRTLGDPITRLDRWETELNTAIPGDERDTTTPASLAADYRALVVGDALAEPERA +QLKSWLLANTTGGKRVRAALPADWTIADKTGSGDYGSASDAAIVWPPNHAPIVIVVQTTK +PDPHAEGDNALIADATRLAIQ-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas phaseoli pv. syngonii LMG 9055 TaxID=1437878 RepID=A0A1V9HI73_9XANT +--MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRGIGDAQTRTDRYEPQMNRFAAGGPRDTTTPAAIAVTLRTLLLGDALQPASRK +QLTRWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAFAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI000D03F1CF +----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +NGFEKSLKQIGDHVTKSNRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Verrucosispora maris (strain AB-18-032) TaxID=263358 RepID=F4F8K0_VERMA +-------FGPLEQEFDARLGVYAVDTGTGRTI-EHRADERFAYASTFKALAAAAVLKATT +--AEELDQVVRYSRDDLVTYSPITEQHVATGMTLRAIADAAVRYSDNTAGNLLFDRLGGP +AGFKQALRDIGDDVTEPARIETALNAATPGDVRDTSTPRALATSLRAYAVDDALPTEDRD +VLVDWLKRNTTGEKVIRAGTPDGWVVGDKTGSGGYGTRNDIAVIWPPDREPIVLAVLSSR +DAEDAGTDDALLARAAELTL--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. cf386 TaxID=1761904 RepID=UPI000B859647 +--DVTARLRALEQQHGARLGVFAHNLATKRTV-RHRADERFPICSLFKTLAAAAVLRDLD +RDGEVLNKRIHYTAADVVANSTVTEKHVATGMTVAELADAAIRFSDNTAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRATDTTSPRAIGRTYARLVLGNALNRPDRD +LLTHWLLNNTTSVNRFRAGLPRTWSIADKTGGGSYGTNNDAGIAWTEDGTPLVLVVQTTR +PDQDAAPDHALIVETAELLAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000E209619 +----DREFAKLEEKYDAHLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDEVTLPERFEPDLNEVNPGETHDTSTARALAASLQTYVLGQALPEDKRE +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGSGSYGTRNDIAILWPPKGDPIVLAILSDR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB00072 TaxID=1703928 RepID=A0A1Q5A771_9ACTN +------AFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRRYG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAKPERA +RLAQWLTANTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +TDADADYDNTLIAKATSAAV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=A0A1D7VMH9_9ACTN +------DFRELERKYGARLGVYAVNTGDGREV-AFNADERFAYASTFKAFAAAAVLRKYS +--LSGMDKVIKYSRSDLIDHSPITEKHVDTGMTLRDLCDAAVRYSDNTAANLLFDALGGP +QGLAAALAKTGDTTTKVERREPELNQWSPGATQDTTTPRAWAADLRAFVLGDALGKDERE +QLTQWLRTNTTGDELIRAGVPKGWDVGDKTGGGGYAVRNDIAVVWPPGAAPIVMAIMSNR +GTKDADYDNKLIAEAASLVTK-- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=A0A2W5PQW6_VARPD +----AAALARLEEGLSGRLGVFAIDTATGATI-GHRASERFPICSTFKAVLAGALLARGV +REPGLLDERVRYTKADLIAHSPITGRELARGMTVAELCAATVQYSDNAAANLLLRRIGGP +EALTAQARAWGDSTFRLDRWETELNSALADDPRDTSTPEAMARLLRTLAVDDGLPTAQRA +RLQDWLRGNTTGGARVRAGMPAAWTVGDKTGTGAHGAASDIAVVWRPQAAPLVLAVYTRL +EAQDAKPRDDVIAAASRIVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F5P8_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLRLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIHTTG +SQATMDERNRQIAE--------- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFD0469 +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNATGDKLIRAGVPNDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=UPI0011A88403 +-tQAERELAALEHDFAGRIGVCAIDTADGALL-GQRADERFPMCSSFKAVLAAAILARSG +AEPGLLAQHVRYQRGDLLPHSPVTSQHLAEGMSVAGLCEATVQTSDNAAANLLLQRVGGP +AGLTAFMRSIGDAQFRLDRWELELNSSLPGDPRDTTTPRAMAESLRKLAVDDALAPPHRA +QLATWLRGTVTGAARIRAGMPAGWVVGNKTGTSGYGSAIDVAVVWPPARAPLVLAVFTTR +HAADAPALDAPIAQAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. S3-2 TaxID=1747903 RepID=A0A1A7C0X4_9BURK +--DAQAQLAALEQAAGGRLGVSALHTGSGARI-SHRADERFPMCSTFKSMLAAAVLARST +SEPQLMNQLVRYEAKELVTYSPVTEKHVATGMRVAELCAATLQTSDNSAANFLMKILGGP +QAVTAYARSIGNEVFQLERWETELNSAIPGEVRDTTSPEATVKSLYGLLLGTSLPAAQRQ +QLDTWMRGNTTGDKRIRAGVPAGWKVADKTGSGAYGSVNDIGVAYPSGDAPLVIAIYYTR +EQKDAPINQDIITAATRIVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI000BF9C6F5 +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKNVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDNVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPAEKRE +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Chromobacterium sp. LK11 TaxID=1628212 RepID=A0A0J6NKI0_9NEIS +----ARQLAELERNAGGRIGVFAQEVDSGRSL-AYRADERFPMCSTFKLLLVGALLQRSV +AQPDLLYRHVDYRRDQLIDYSPISEQHVEQGMSVKDLCDAAMRFSDNTAANLLLEQLGGP +QEVTRFARSLGDGQSRLDRIEPELNLAEPDDPRDTTTPAAMTANLHALLFSPLLPERQRG +LLNDWLLGNTTGNLRIRAGLPAEWRVGDKTGSGGHGAANDVAVAWRPGKSPLLLSVYYWG +SSAMMDERNAVIAAVARVAAAEf +>[subseq from] class A beta-lactamase n=1 Tax=Ensifer sp. 1H6 TaxID=1911585 RepID=UPI0009C98047 +---VDTRLAELEKCTGGRLGVSVLDMETNVSF-GRRESERFAMCSSFKTLAAGFALARAD +QGAEKLDRRIVVAQKDIVAHSPVTEKHVGGEMTIAELCAATLTTSDNAAANLLLENFGGP +PALTAWLRTIGDETTRLDRNEPALNEAKVGDPRDTTTPAAMLETLGNLAFGPVLAEASRK +LLIEWMVANTTGDLRIRAGLPKAWKVGDKTGTNGNGAASDIAIVWPEGRGPLLIAVYIAE +ATAPLAELNTVFADVGRMAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD7D342 +--EIDRRIGALEKQIGGRIGVSAIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD +KGEENLERRVVYEKEQLIAYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLILESLGGP +KELTNWLRTLGDGSTRLDRIEPDLNDIAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK +TLIEWMVGNTTGNERLRTGLPETWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTN +ATVATAEINPVFGEVGRIVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum robiniae TaxID=2014887 RepID=UPI0009A20113 +---IRQKLAELEKQSGGRLGVMAIDNASSDRV-GYRETERFPFCSTFKIVLVGAILNRSL +ENGSLLQRRVRYGAGELVAYSPVTEKAVGAGMTVSGLCAAALQYSDNTAGNLLIRELGGI +AAVNEYARKIGDQGFRLDRMETELNSAVPGDERDTTTPLAMAQTLQGLTLGETLPELQRR +MLVDWMRGNTTGGTRIRSAMPRDWQIGDKTGGGDYGTTNDVAVIWPGSESPVVLAIYFTQ +TAKDAPMRNDVVAEAARIVGEHf +>[subseq from] Beta-lactamase Ohio-1 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=BLA1_ENTCL +-----EQIKLSESQLSGSVGMIEMDLARPGTLtAWRADERFPMMSTFKVVLCGAGLARVD +AGDEQLERKIHYRRQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLPAVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTARSMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGRLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIAGALIEHw +>[subseq from] Class A beta-lactamase n=2 Tax=Bacillus megaterium TaxID=1404 RepID=A0A6B3RB43_BACME +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQKYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDQIVLAILSNR +AEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC05858 TaxID=2487409 RepID=A0A3R9U7Q4_9ACTN +-----GEFKKLERSYDARLGVYAIDTGTGHEV-AYRDGERFGYASTFKALEAGAVLQKVK +--LGGLDRVITYSKDDLIDNSPVTEKHVDTGMSLAALCDAAVRYSDNTAANLLFDQLGGP +KGLDAMLEKMGDDVIQMERREPELSRWVPGSTRDTSTPRAMAEDLRAFVLGDVLGDGERA +QLTKWLRTNTTGDALIRAGVPKNWQVGDKTGTGSYGGRNDIAVVWPPDSAPIVMAIMSNR +GDKDATSDDKLIADAAHVVADQ- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. TSRI0369 TaxID=1703936 RepID=A0A1Q5HEE8_9ACTN +-----AELAALERRFGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAVLAATS +--DADRDRVLRYRRADLVAHSPVTERHVDTGITLRDAAEAAVRHSDNTAGNLLFDALGGP +AGFARALRDAGDRVTRPVRTEPELNAATPGDTRDTSTPRALVGSLRAYTLGDALPPADRD +LLLGWMRASTTGSALVRAGTPAGWQVADKSGTGGYGTRNDIAVVWPPDGAPIVLAVLTSH +DSRDAKPDDALVAQAARATV--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia arthritidis TaxID=228602 RepID=UPI000A04569F +---ANTSVADLEARYGAQIGLFAVDTGTGRTV-THRADERFPFLSTFKTLAAAALLRSHP +LDTGYFDRVIRFHEADLVEYSPVTSAGVAEGMTLARVAEAAITRSDNTAGNLLLRELGGP +EGLTAFLRTLGDPASRLDRWETELNTAIPGDERDTTTPAALAADYRAAALGDALGAPERD +QLVAWLKANTTGGKRIRAGLPANWVTGDKTGTGSYGSANDVAIVWPEGGAPMVIAILSRK +SDADAEANNDLLAEVTKVAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WMMB 714 TaxID=1286822 RepID=A0A1C6PQA9_9ACTN +-kQAARELRKLEEKFGARLGVYAVDTGSGEEV-AYKDRERFAYASTFKALAAGAVLRKYG +--PDRMDRVIEYSRDDLVDYSPVTEKHVGTGMSLRALCDAAVRHSDNTAANLLFDALGGP +KGLDAALERLGDDVTRMERREPELSRWKPGSTPDTSTPRAIAGDLRAYVLGDALRKPERS +QLAEWLRRNTTGDGLIRAGVPEGWKVGDKTGTGGYGVRNDIAVVWPPRAAPVVMAIMSNR +SGEDAEPEDELIAEAASAVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis gilva YIM 90087 TaxID=1235441 RepID=A0A223SAI8_9ACTN +--SFEQEFKQLEKEFDARLGVYAIDTGTDEAV-SYRADERFAYASTHKAFSAGAVLQQTP +--LEELDDIVTYAEDDLVSHSPITEKHVDTGMPLRDVVDAAIRYSDNTAANLLFRELGGP +KGLGEALKEMGDETTHVDRVETELNEAAPGDIRDTSTPEAMATTLRKFTLGDTLPADKRE +ILTDMLKGNTTGDNLIRAGVPDDWTIGDRTGGGGYGTRNAIAVAWRPNGDPVVFAIMSSR +DDKDAEWNDKLVAEATEIAVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. CF097 TaxID=1500301 RepID=UPI00055FB720 +-nDIAQQLASLEERTGGRLGVSVLDTNTNVSF-GHRQDERFAMCSTFKALAAAFVLARVD +KGEENLDRRIAVSNADLLSHSPIAEKHLADGMTVGELCGAAVTYSDNAAANLLLASFGGP +VGLTAWLRSIGDETTRLDRTEPALNEAKLGDPRDTTTPVAMMRTLGRLLLEDVLSPPSRD +RFAAWLVANTTGGRRLRAGLPGGWTVGEKTGTNGKGAAGDIGFMRPREGHTILASVYIAE +AMKPVKELEPIFAEVGKLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000A365992 +-----DSFVKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS +--IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTGKRE +LLVDWMKRNTTGDKLIRAGVSKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADATKVVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Thermoactinomyces sp. DSM 45891 TaxID=1761907 RepID=A0A1K1VDT9_9BACL +--DVNQAFTDLEKKFEARLGVYAIDTGTGRTV-THRSDERFAYASTFKTLIVGMLLKQKS +--VDQLNELITYTKEDVTRYAPITEKHIDTGMTLRELCDATLRYSDNAALNLILEEIGGP +KVARQELMRIGDHTTKPSRFEPDLNEATPGDIRDTSTPKALATSLKAFTLENVLPMEKRN +MLIDWMKRNTTGDKLIRAGVPDGWIVGDKTGSGGYGTRNDIAIVWPPNRAPIVIAMLSSR +GEKDATYNEELIAQATKEVVH-- +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum robiniae TaxID=2014887 RepID=A0A246WWD7_9BURK +---IRQKLAELEKQSGGRLGVMAIDNASSDRV-GYRETERFPFCSTFKIVLVGAILNRSL +EDGSLLQRRVRYGAGELVAYSPVTEKAVGAGMTVSGLCAAALQYSDNTAGNLLIRELGGI +AAVNEYARKIGDQGFRLDRMETELNSAVPGDERDTTTPLAMAQTLQGLTLGETLPELQRR +MLVDWMRGNTTGGTRIRSAMPRDWQIGDKTGGGDYGTTNDVAVIWPGSESPVVLAIYFTQ +TAKDAPMRNDVVAEAARIVGEHf +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sinuspersici TaxID=501010 RepID=A0A1V3BZI0_9ACTN +---LAREFERLEKEFDARLGVYAVDTGTEEEV-VHRPDERFAYCSTHKAFSAGAVLQRNT +--PEEMEEVITYTEDDLLDYAPITEQHVDTGMTLMELTDAAVRYSDNTAANLLFEELDGP +DGFEEAMEAVGDDVIEADRVEPGLNEAVPGDIRDTSTPRAMAESLRKFTLGDALPEDRRD +VLTDMLVNNMTGDELIRAGVPEGWEVGDKTGSGGYGTRNDIAVLWPPEGEPIVLAVMSSR +DEEDAEYDNALIAEAAEVVVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=I6VDW2_KLEPN +-----EQIKQSESQLSGRVGMIGMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPA-------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI000BA62BB9 +---TIKKFEQLEKEYDARLGVYAIDTGTKETV-EFHENERFAFTSTHKALAVGALLQQKS +--IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP +AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDTLPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DEKDADYNDELIADATEEVIK-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora ureilytica TaxID=709868 RepID=A0A3N9XHJ8_9ACTN +--AADQEFRRLEEQFGARLGVYAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT +--DAQLDRVVRYSARDLVAHSPVTEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +AGFESKLRALGDTVTEAARYETSLNEGTPGDKRDTSTARALVGDLRAYTVGVALEPTDRD +VLRGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DKKDATPDDALIAQATRVVVA-- +>[subseq from] Beta-lactamase n=2 Tax=Actinomadura hallensis TaxID=337895 RepID=A0A543IAB4_9ACTN +--EVTERISRLEKTRGLRIGAYAVDTGTGRRV-GHRADERFPFASTFKAMACGAVLRRAD +SDPGLLDRVVRYGKGDLLAHSPVTEKHVKTGMTVADLCRATVTTSDNTAGNLILKEIGGP +AGLTGFLRSLGDRVTRADRWEPGLNDWRPGEERDTTAPRPWADDLRALTVGDALAPEDRE +RLTGWLKATVTGEGRIRAGLPDGWTAGDKTGTGGYGSANDIAVVWPPSGAPLVIAILTTG +RDADAEPDERAIAETTAVLVD-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase Sme-2 n=3 Tax=Serratia marcescens TaxID=615 RepID=Q9F7U6_SERMA +--AAAKQIKKLEEDFDGRIGVFAIDTGSGNTF-GYRSDERFPLCSSFKGFLAAAVLERVQ +QKKLDINQKVKYESRDLEYHSPITTKYKGSGMTLGDMASAALQYSDNGATNIIMERLGGP +EGMTKFMRSIGDNEFRLDRWELELNTAIPGDKRDTSTPKAVANSLNKLALGNVLNAKEKA +IYQNWLKGNTTGDARIRASVPADWVVGDKTGSCGYGTANDYAVIWPKNRAPLIVSIYTTR +KSKDDKHSDKTIAEASRIAIQ-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ru87 TaxID=2044307 RepID=A0A2B8AMJ1_9ACTN +----ARELKDLERKFDARLGVYAIDTGTGREV-VHNDGERFPYASTFKALAAGAVLHKHT +--PDGMEKVIEYSEDELVHHAPVTEKHVGSGMTLRELCDAAVRFSDNTAANLLLKELGGP +DKLEAVLREAGDDVTRMDRYEPELSRWSPGSTLDTSTPRAMARNLRAFVLGDVLGKDDRD +QLTTWLRTNTTGDELIRAGMPEGWVVGDKTGSGGYGARNDIAVVWPPDSDPIVMAVMSNR +AEKDDAYDNKLIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CNZ289 TaxID=2572907 RepID=A0A559TY19_9ACTN +-----RELAALEREYDARLGVYAVDTGSGREV-AYRAGERFPYASTFKALAAGVVLRTHS +--ARELDKVVTYSADDLVAHSPVTGEHVATGMTLRDLCEAAVRYSDNAAANLVLAELGGP +AGMDAELEALGDDVTRMVRDEPELSRWHPDDTRDTSTPRALAEDLRALVLDDALDKRDRA +RLTEWLRTNTTGDTLIRAGVPETWRVGDKTGTGSYGARNDIAVLWPPDRAPIVLAVMTNR +TQRDAEPDDALLADAASAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. Soil531 TaxID=1736389 RepID=A0A0Q9V8V2_9BACI +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLEQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTARALATSLQKYVLGQALPEDKRE +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces filamentosus TaxID=67294 RepID=UPI00123871E0 +--RAEARFRALEERYTARLGVHAYDVRTGRTL-AHRDRERFPMCSVFKTLAVAAVLRDLD +HDGGFLARRVHYTAADVERWSPVTEDNIARGMTVAELCDATLRFSDNTAANLLLRDLGGP +TAVTRFARSAGDPVTRLDRWEPELNSAEPWRITDTTTPRAIARTYGRLLLGRVLDPADRA +LLTDWMLRNTTSDARFRKGLPADWTVADKTGGGDYGGNNDVGVTWPPDGGPILLAVLTTR +PDRDAEGVDELVAAAAAIAADE- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces noursei TaxID=1971 RepID=A0A2N8PI94_STRNR +----AAELRELERRYAARLGVYARNARTRQVV-AHRAQERFAMCSTFKTVAAAAVLRDHA +-HCAPLDKVIHYPARDILPYSPKTQEHVDTGMTVGDLCAAAIQYSDNAAGNLLLRQLGGP +EGLTRFFRSIGDPTSRLDRWEPDLNTAVPGDLRDTTTPEAIGTSYGRLALGRVLTHDARE +QLVTWLKGNTTSEHRFRAGLPQHWVVGDKTGTGDYASANDVGVAWTGRSTPIVLAVLSTK +SAKDAPVDEALIADAARIVAR-- +>[subseq from] Beta-lactamase n=3 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2Q9_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPINQSDLVTYSPVTETWVGQDISLDALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMASSLHELLLGEVLSPAAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPSQAPLIAAIYLTQ +SDASMEQRNAAIAAIGTALAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. st140 TaxID=1828052 RepID=UPI000BEF3835 +------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALPAPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. CP22 TaxID=2580517 RepID=UPI0012BBF1F3 +------DFAPLEREFDARLGVYAVDTGTGHTV-THRADERFAYASTFKALAAAAVLAATP +--TEELDRVVSYSRDDLVTYSPITERHVDTGLSLRAIADAAVRYSDNTAGNLLLDRLGGP +DGFKQVLRDLGDEVTEPARWETDLNAYVPGDDRDTSTPRALATTLRAYAVDDALSAQDRA +VLVDWLKRNTTGDTTIRAGTPDGWEVGDKTGTAAHGTRNDIAVVWPPERAPIVLAVLSSR +DRPDADSDDSLLARAAELTLD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces antibioticus TaxID=1890 RepID=A0A0L8PLE0_STRAT +----HAELAELERRYGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDQA +-DCAPMDRVVHYPPHDILPNSPRTEENLATGMTVADLCAAAIQYSDNAAGNLLLRELGGP +AGLTRFYRSLGDEVSRLDRWEPELNTAIPGDPRDTTTPEAIAASLERVTLGRALARADRE +RFVGWLKGNTTSSARFRKGLPREWVVADKTGTGDYATANDIGVAWTTRRTPLVLVVLSSR +TTPDAPVDEALIADAAAVVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. (strain ORS 278) TaxID=114615 RepID=A4YV89_BRASO +--DFQETIAGIEADSAGRLGVALLDTASGALS-GHRLDERFPMCSTFKALLAAAILTKVD +AGAEQLSRRLPITQGDILSYAPVTKLHVGTSLSIGELCEATVTLSDNTAANLLLATLDGP +AGLTRATRGFGDAITRLDRIEPALNESVPDDPRDTTTPAAMAQTLAKLTTGNALSTSSRD +VLNGWLIGCKTGAARLRAGLPASWRVGDKTGSGENGSSNDVAVIWPAGRAPVIVTSYLTE +TKASDEKRNAAHAAVGRAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0004BD31E7 +----TARLRELEQEHTARLGVYARNMRTGRTV-AYRADERFPMASLFKTLAAAAVLRDLD +RDGEFLARRVYFTQDDVDKYSEVTKHHVATGMTIGELCDATIRFSDNTAGNLLLEELGGP +TAVTRFCRSIGDPVTRLDRWEPELNSAEPWRVTDTTSPRAIGTTYARLVLGTALEPRDRG +RLTDWLLGNTTSVERFRKGLPADWLLADKTGGGQYGSNNDVGITWPPGGTPIVLSVLTTQ +PEEDAPADNALVARTAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas meridiana TaxID=29570 RepID=UPI001320291C +--RIAAELERIEQTLDARIGFAAHNIATGQRW-EVNADERFAMSSTFKTLACGALLEQVD +EGQLALETEVSFEASELVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLVLQALGGP +EAITAFVRSMDDPVTRLDRYETELNEATPGDERDTTTPNAMLATLEKLVLGDVLSDESRQ +QLEAWMMGNAVADGLFRAAMPFDWIIADRTGAGGYGSRSITAIIWPPEQAPTVVVLYITE +TEASFEERNAAIASLGEVVQ--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ms115 TaxID=1827928 RepID=UPI000BF005D7 +------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALPAPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. YR528 TaxID=1500258 RepID=UPI000645C1EF +--EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD +KGEENLERRVVYEKEQLIAYSPETEKHVGGEMSVGDLCKAAITLSDNTAANLILESLGGP +KELTNWLRTLGDGSTRLDRIEPDLNDIAKDDPRDTTTPDAMLDTLGNITLGSVLSEPSQK +TLIEWLVANTTGNERLRTGLPETWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTN +ATVATAEINPVFGEVGRIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=A0A1S2C287_9BACI +---SDREFAKLEDKYDANLGVFALDTGTNKTI-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDNVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPAEKRE +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAVLWPPNGDPIVLAILSDR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Verrucosispora sp. ts21 TaxID=2069341 RepID=A0A2N7T873_9ACTN +-------FGPLEQEFDARLGVYAVDTGTGRTI-EHRADERFAYASTFKALAAAAVLKATT +--AEELDQVVRYSRDDLVTYSPITEQHVATGMTLRAIADAAVRYSDNTAGNLLFDRLGGP +AGFKQALRDIGDDVTEPARIETALNEGTPGDVRDTSTPRALATSLRAYAVDDALTTEDRD +MLVDWLKRNTTGDKVIRAGTPDGWVVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DAEDAGTDDALLARAAEL----- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces antimycoticus TaxID=68175 RepID=UPI000A363504 +-----GEFKKLERSYDARLGVYAIDTGTGHEV-AYRDGERFGYASTFKALEAGAVLQKVK +--LGGLDRVITYSKDDLIDNSPVTEKHVDTGMSLAALCDAAVRYSDNTAANLLFDQLGGP +KGLDAMLEKMGDDVIQMERREPELSRWVPGSTRDTSTPRAMAEDLRAFVLGDVLGNGERA +QLTKWLRTNTTGDALIRAGVPKNWQVGDKTGTGSYGGRNDIAVVWPPDSAPIVMAIMSNR +GDKDATSDDKLIADAAHVVADQ- +>[subseq from] class A beta-lactamase n=1 Tax=Verrucosispora sp. CWR15 TaxID=2499994 RepID=UPI00140DC5CC +-----VDFAPLEREFDARLGVYAIDTGSGSTV-AHRAEERFAYASTFKALAAGAVLAATS +--DEELDRVVSYSRDDLVTYSPITERHVDTGLSLRAIADAAVRYSDNTAGNLLLKQLGGP +SGFRQALREVGDEVTEPVRWETELNAYVPGERRDTSTPRALATTLRAYAVDEALSPADRA +VLVDWLKRNTTGDKTIRAGVPEGWAVGDKTGSADHGTRNDIAVIWPPERAPIVLAVLSDR +TEPDAERDDALLARAAELTLD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 769 TaxID=1262452 RepID=A0A0A8EYY4_9ACTN +----AAELRDLERRYAARLGVYARNARTGQVV-AHRAQERFAMCSTFKAVAAAAVLRDHA +-HCAPLDKVIHYPARDILPHSPKTQEHVDTGMTVGDLCAAAIQYSDNAAGNLLLRQLGGP +EGLTRFFRSIGDPTSRLDRWEPDLNTAVPGDLRDTTTPEAIGTSYGRLALGRALTHDARE +QLVTWLKGNTTSEHRFRAGLPQHWAVGDKTGTGDYASAHDVGVAWTGRSTPIVVAVLSTK +SAKDAPVDEALIADAARIVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces melanosporofaciens TaxID=67327 RepID=A0A1H5B2L8_STRMJ +-----GEFKKLERSYDARLGVYAIDTGTGHEV-AYRDGERFGYASTFKALEAGAVLQKVK +--LGGLDRVITYSKDDLIDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGP +KGLDAMLEKMGDDVIRMERLEPELSRWVPGSTRDTSTPRAMAKDLRAFVLGDVLGNGERA +QLTKWLRTNTTGDALIRAGVPKDWQVGDKTGSGSYGGRNDIAVVWPPDSAPIVMAIMSNR +GDKDATSDDKLIADAAHVVADQ- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2A8Q898_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH +DKEDAEYDDILIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. (strain ORS 278) TaxID=114615 RepID=UPI000319B68B +--DFQETIAGIEADSAGRLGVALLDTASGALS-GHRLDERFPMCSTFKALLAAAILTKVD +AGAEQLSRRLPITQGDILSYAPVTKLHVGTSLSIGELCEATVTLSDNTAANLLLATLDGP +AGLTRATRGFGDAITRLDRIEPALNESVPDDPRDTTTPAAMAQTLAKLTTGNALSTSSRD +VLNGWLIGCKTGAARLRAGLPASWRVGDKTGSGENGSSNDVAVIWPAGRAPVIVTSYLTE +TKASDEKRNAAHAAVGRAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Rummeliibacillus stabekisii TaxID=241244 RepID=A0A511C0F3_9BACL +----TEAFKKLESEFDARLGVYAIDTKTKKSI-SYQSDERFAFASTYKALATGAMLKQKS +--MKDLDKIITYTKEDLVTYSPITEKYVDTGMTVKDIATAAIRYSDNTAGNLLFNELGGP +NGFEKALRKMGDKVTQSNRLEPELNLTTPGDLRDTSTPRALASNLQKFVIGDVLPTKKKA +LLTDLLVGNATGDTLIRAGVPKDWVVADKSGAGGYGTRNDIAVVWPPDRKPIVIAILSSR +NTKDATYDDALIAKAAKVVVN-- +>[subseq from] Beta-lactamase n=1 Tax=Microbacterium sp. ABRD_28 TaxID=2268461 RepID=A0A3G6ZI46_9MICO +---LGAELGALEATYDARVGVYALDTETGQTV-AHRADERFAYASTFKALLAGVVLHEID +----DLDRVVTYNSEALVSYSPVTEQYVATGLSIGELAEAAVRTSDNTAANLLLDQLGGP +EGFAAALARSGDEITQPERREPELNSAVPGDPRDTSTPRALVETLRQYALGDLLADAEKQ +TLIDWMSGNRTGDTLIRAGAPEGWTVADKSGTGGHGTRNDIGLVWPPDGEPIVIAVLTTR +GVGDAATDDALVAEAAAVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Hydrogenophaga sp. BA0156 TaxID=2716225 RepID=UPI00140805C1 +---LAAALRAIESRAQGRLGVHVIDSGSGREW-GHRSDERFMMLSSFKTLAAALVLARAD +QGLAPLAQRVRYGRAELVSWSPVTERHVGGELTLAELCEATITTSDNTAANLILANVGGP +AALTAFLRRIGDPVTRLDRTEPELNRPVPGQDLDSTTPRAMARTLRTLLLGDVLSAEASL +QLAAWLRANTTGGKRLRAGLPPDWGVGEKTGTAGR-SANDAGIVWPPRGAPLLVSAYLAD +SEAPAEQREQALAEVARLIAR-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2B5D3F3_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGSP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI000EF9CE1B +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +D---------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces scopuliridis RB72 TaxID=1440053 RepID=A0A2T7T9R8_9ACTN +-------LHELERKFDARLGVYAVDTGTGREV-AYNDGERFPYASTFKALAAGAVLRKYS +--LSGMDRVITYSKDDLIANSPVTEKHVETGMTLKELCDATVRFSDNTAANLLFDHLGGP +KGLEAVLREIGDDVTLMERREPELSRWVPGDTRDTSTPRALVEDLRAFVLGDVLGKAERA +QLTEWLRTNTTGDALIRAGVPKGWVVGDKTGTGSHGARNDIAVVWPPDSAPIVMAIMSNR +PDKDAEHDDELIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=unknown TaxID=N/A RepID=UPI00143E694A +hrDTRARLRELEARHGARIGAFAYNLRTRATV-RHRAAERFPICSVFKTLAAAAVLRDLD +RHGETLARRIHYTVADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PAQDAAADSPLVAATASVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Janthinobacterium TaxID=2610881 RepID=UPI000A320E98 +---AHTQLAALEQAAGGRLGVSAWRQGGELRI-AHRADERFPLCSTFKAMLAAAVLAHSA +SEAGLLAQRVRYEKKDLVTYSPITEKHLADGMTVAELCAATLQYSDNSAANFLMKILGGP +QAVTAYARSIGNKEFQLERWETELNSAIPGEVRDTASPASMARSMEQLLLGDGLPAPQRQ +QLDTWMRGNTTGDKRIRPALPDGWKVADKTGSGAYGSINDIGVAYPPVGAPLVIAVYYTR +ELKNADNNQDIITAATRIVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Microbispora rosea TaxID=58117 RepID=A0A1N7EH57_9ACTN +-----SQFAALERKHGARLGVYVLETGTGASL-AYRADERFAFCSTFKALAAAAVLHQNP +--VSHLGKRVTYTGADVNSISPITKDHIATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP +ARLTAYLRRLGDTVSRMDNYEPELNRDRPRDPRDTTTPRAIAADYQKLVLGEALSAGKRA +LLKDWLVRNTTGAKRVRAGLPKGWTVADKTGTGDYGRANDIAIVWPPHTAPLVMAIMSDR +PGYHTPPKDSLIAEATARIV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hirsutus TaxID=35620 RepID=UPI0006E25F02 +------DFKELERTYGARLGVYAVDTDNGREV-AYNDNERFAYASTFKAFAAAAVLRKYS +--LSGMDEVITYSRDDLIAHSPVTEKHVDTGMTLRELCDAAVRHSDNTAANLLFDALGGP +KGLASALEEVGDTATRVERREPELNQWAPGATRDTTTPRAWAGDLRAFVLGDMLGRKERA +QLTKWLRTNTTGDELIRAGVPHGWVVGDKTGGGGYGVRNDIAVVWPPDAAPIVMAIMSNR +GTEDADYDNKLIEEAASVVTR-- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. RAC01 TaxID=1842533 RepID=A0A1B3PMR2_9BURK +--RWRETMAGIEQAAQGRLGVAMLDTGTGLAL-GWRQDERFAMCSTFKLVLAGWMLALVD +QGRERLDARVHYAAADVVAYSPVSGPRAGSGLTVAELCAATVSLSDNTAANVLLARHGGP +AAFTAFVRSLGDTVTRLDRTEPTLNEAAVGDPRDTTTPMAMLQTMHKLVLGDALSPASRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPPGGAPVLVTCYLTR +SSATPEQRDAAIAQVARAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=alpha proteobacterium Mf 1.05b.01 TaxID=1282876 RepID=UPI0009E0102B +---ILETVRTIESRLGGRVGISVHDTGSDQRW-VYRSDERFPISSTFKPFACAAILSRIE +NGSERLHRVIDITEEDLVTYSPVTETRVNTVMTIAELCEATITLSDNTAGNLILESLGGP +KAFTDYMRSIGDDTTRLDRWETDLNEGTPGDRRDTTTPSAATTSLSHLLLGPTLSNSSRE +QLTTWMENDKVADALLRSALPEGWRIADKTGAGGHGARSIIAIIWPTAEKPIVISIYMAE +SEANFAERNEAIAEIGAAIVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas albilineans TaxID=29447 RepID=UPI0005F3358A +--ALQQRLAEIERRSGGRLGVYLLDSGTGQRI-GRREQERFPLCSTFKFVLVAAVLQRVD +RGEVGLDQRVRVRAADVVSYAPVTKPHVGGTLSVDALCRAAMIFSDGGAANLLLRLVGDP +PGLTRFLRAHGDTQTRSDRNEPSMNAFALDDPRDTTTPAAMASTMRTLLLGDVLQPASRQ +RLIDWMIDNRTGDDCLRAGLPAGWRIGDKTGNNGTDSRNDIAIVWPPGRAPLLLTAYLNM +ATVDSDARDAALKAVAQAVVAWw +>[subseq from] class A beta-lactamase n=1 Tax=Pectobacterium versatile TaxID=2488639 RepID=UPI000F8CE1B6 +-pDTLNTVKDAENKLKARVGYTELDLTNGMILeGYRPEERFPMMSTFKVLLCSAVLSRVD +SGKEQLDRRIHFHQSDLVTYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLSTIGGL +QELTIFLRKTGDHVTRLDRWETALNEALLGDERDTTTPKAMAETLHKLLTGKILTVASQQ +QLMDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYLTG +SQATIEERNKQIAEIGTSLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Sediminibacillus halophilus TaxID=482461 RepID=A0A1G9TAA4_9BACI +--DLDEEFSQIEEAFDARLGVYAIDTGTNQSV-KYNPDERFAYSSTFKLLASAFLLKQND +--LKDLEKVVTFGKDDLVTYSPVTEKHVDTGMTLLEISEAAIRKSDNTAGNLLLNALGGP +ENYKQALREIGDDVTQPERYETELNEFSPGNKRDTSTPRALANNLRKVVLGDFLPREKQE +LLIDWMKGNATGDALIRAGKPEGWTVGDKSGAGSYGTRNDIAIVWPPGREPIVIAVMSRH +KKKDAKYDDELVARAAEVTLNAf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8YSH5_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNP +--INKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEVAVRSSDNTAGNLLFNKIGGP +KGYEKALRQIGDRVTMAERFETELNEATPGDIRDTSTAKTLATNLKDFTVGNALPADKRK +ILTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR +DEKEATYNNELIAQAAEVVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces pini TaxID=1520580 RepID=A0A1I4GFS6_9ACTN +---SHERLVQLEREFDARLGVYALATGTGSTI-AHRADERFAFCSTFKGLAAAAVLDRNP +--ISHLDTLVTYTGNDLMPHSPFTRKNVDRGMTIRQLCDAAVRYSDGTAGNLLIRELGGP +EELTAYVRGLGDTVTRMDRIEPEISQAVPNDPRDTSSPRAMGGDYRKVVLGNALSAEKRA +FLRDLLERNTTGDQRIRAGLPQGWRVADKTGTGQYGTLNDIAVAWPPGSEPLVIAIMSSK +AVQDAERDQALLAEAAAYVAK-- +>[subseq from] Beta-lactamase n=2 Tax=Xanthomonas sacchari TaxID=56458 RepID=A0A2P5Z351_9XANT +-qTLQQRLAEIERRSGGRLGVSLLD-GSGATLgWQRQDERFPLCSTFKFLLAGAVLQRVD +RGELSLERRLPVRKADLLANAPVSERHVGGSLSVVEMCRAAMIYSDNTAANLLLPLVGDP +PGVTRFLRALGDAQTQLDRNEPGMNEFVAGDPRDTTTPAAMAATMRALLLGQVLQPVSRQ +RLIDWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG +ATVDSAARDATLKAVAQAVVA-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B4AC2E8 +-qATHKEFSQLEKKFDAQLGVYAIDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDTLNEVIKFRKEDLVDYSPITEKHIDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP +KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKVIATNLKDFTVGNALPDDKRK +VLTDWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK +DEIEAIYDNQLIAEAAEVVVNTf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NBRC 110611 TaxID=1621259 RepID=UPI00082BB0DE +------EFKKLERKFDARLGVYAIDTGTGREV-AYNDGERFGHHSTFKAFAAGAVLRKHS +--LGGMDKVIKYSSDDLVDNSPITEKHVATGMTLRELCDAAVRYSDNTAANLLFADLGGP +KALNAVLKELGDDVTRMARIEPELSNWVPGEKRDTSTPRALAEDLRAFVLGDALGKAERE +QLTQWLRTNTTGAELIKAGVPKNWVVGDKTGAGSYGARNDIAVVWPPDGAPIVMAILTNR +TTKDAVFDNKLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces antimycoticus TaxID=68175 RepID=A0A4D4K1T9_9ACTN +------AFKKLERSYDARLGVYAIDTGTGHEV-AYRDGERFGYASTFKALEAGAVLQKVK +--LGGLDRVITYSKDDLIDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGP +KGLDAMLEKMGDDVIRMERREPELSRWVPGSTRDTSTPRAMAKDLRAFVLGDVLGDGERT +QLTKWLRTNTTGDALIRAGVPKDWQVGDKTGSGSYGGRNDIAVVWPPDSAPIVMAIMSNR +GDKDATSDDKLIADAAHVVADQ- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3Q8GUV0_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVARPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia exalbida TaxID=290231 RepID=UPI0005938A4E +--AANTSVADLEARYDAQIGLFAVDTGTGRTV-THRADERFPFLSTFKALAAAALLRSHP +LDTGYFDRVIRFHEADLVEHSPVTSAGVAEGMTMARVAEAAITRSDNTAGNLLLREIGGP +EGLTAFLRTLGDPASRLDRWETELNTAIPGDERDTTTPAALAADYRASALGDALGAPERD +QLVAWLKANTTGGERIRAGLPANWVTGDKTGTGSYGSANDVAIVWPEGGAPIVIAILSRK +SDADAEANNDLLAEVAKVAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces cinnamoneus TaxID=53446 RepID=UPI000903B201 +------ELKELERKFDARLGVYAVDTGTGREV-AYNDGARFAHASTFKALAAGAVLKKYS +--LSGLDRRVTYSKDDLVDYSPVTEKHVETGMTLRELCDAAVRYSDNTAGNLLFGALGGP +KGLDAVLEGMGDDVTQMERREPELNLWAPGETRDTSTPRALAKDLRAFVLGDALGKGERA +QLEQWLRNNTTGGELIRAGVPKGWAVGDKTGAGQYGTRNDIAVVWRPGAAPVVMAIMSNR +TKKDDKYDNKLIAEATSVIT--- +>[subseq from] Beta-lactamase n=1 Tax=Fictibacillus arsenicus TaxID=255247 RepID=A0A1B1Z7K7_9BACI +------VFAKLGEKFDAKLGVFALDTGTNQTV-NYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNKTITYTREDLVTYSPITEKHVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP +TGFKKALEEIGDNVTTPERFEPDLNEVNPGETHDTSTPRALATSLQAFTLGDKLPTEKRE +LLIGWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR +DQKDADYNDKLIAEATKEVIK-- +>[subseq from] Beta-lactamase n=1 Tax=Modestobacter caceresii TaxID=1522368 RepID=A0A098Y6C6_9ACTN +---VGEALTALEGEFDARLGLYAVDTGSGQVV-AHRADERFGYASTHKALSAAAVLDRTT +--DAELDQVVTYTAEDLVTHSPVTEAHVGAGLPLRELAAAAVQHSDNTAANLLFDRLGGP +AGLEQALRDLGDDVTSVDRTETALNTAVPGDVRDTSTPRALATDLQAVLLGDALDPADRD +LLTGWMRDNATGGTLVRAGVPADWQVADKSGGGGHGTRNDIAVVWPPDGAPIVLAVLSSR +DEADAEYSDALIARATDIAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus massiliensis TaxID=1465765 RepID=UPI0011C7234E +-eELAQEFKQLENEFDARLGIYAIDTETEKSV-VYRADERFAFASTYKALAAGVLLDQKT +--MNELEKIITYTEDDLVTYSPITEKHVDTGMSLKEVAEAAIRYSDNTAGNLLFKELGGP +AGFEAALREIGDTVTESVRFEPDLNFTVPGDSRDTSTPRELATNLQTFVLSDLLPSEERE +LMTDWLVGNSTGDTLIRAGVPENWVVGDKSGAGMYGTRNDIAIVWPPDRGPIAISILSDR +DTEDATYDDALIAEAAKIVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Acrocarpospora pleiomorpha TaxID=90975 RepID=UPI0012D349AE +-----SRFAALERKHDARLGVYALATGTGATV-TYRADERFAFCSTFKALAAAAVLHQNP +--LSHLNKRVTYTSAEVNSISPITEDHIATGMTIRQLCDAAVRYSDGTASNLLVRDIGGP +AQLTAYLRGLGDTVSRIDNYEPELNRNPPRNPRDTTTPRAIAADYHKLVLGDALTTGKRA +MLKDWLERNTTGDKRIRAGVPQGWTVADKTGTGNYGRANDIAIVWPPNTAPLVMAIMSDR +SGYSTPHKESLIAEAAARIV--- +>[subseq from] class A beta-lactamase n=1 Tax=Verrucosispora sp. CWR15 TaxID=2499994 RepID=UPI0013DC34D5 +-----VDFAPLEREFDARLGVYAIDTGSGSTV-AHRAEERFAYASTFKALAAGAVLAATS +--DEELDRVVSYSRDDLVTYSPITERHVDTGLSLRAIADAAVRYSDNTAGNLLLKQLGGP +SGFRQALREVGDEVTEPVRWETELNAYVPGERRDTSTPRALATTLRAYAVDEALSPADRA +VLVDWLKRNTTGDKTIRAGVPEGWAVGDKTGSADHGTRNDIAVIWPPERAPIVLAVLSDR +TEPDAERDDALLARAAELTLD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces roseochromogenus subsp. oscitans DS 12.976 TaxID=1352936 RepID=V6KXM5_STRRC +-----AELTDLERRHGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDHG +-RCAPLDTVIHYPPHDILPHSPRTEEHVDTGMTVADLCAAAIQYSDNAAGNLLLRQIGGP +DGLTRFFRSLGDGTSRLDRWEPELNTAIPGDRRDTTTPEALGRGFERLTLGRALARADRA +QLVTWLKGNTTSAARFGAGLPRDWVLADKTGTGDYGTANDIGVAWTTRGTPVLLTVLSSK +TAQDAAADDALVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0010221E5C +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +S---------------------- +>[subseq from] Beta-lactamase n=1 Tax=bacterium YEK0313 TaxID=1522316 RepID=A0A0A1P325_9BACT +-qELGARLAALEARSGGRLGVGVLDTATETRG-GHRVGERFAMCSTFKSIAAAHVLARVD +RGEERLDRRVIFAESDLVPYSPATKPRAGGQMTMGEICEAAVVLSDNTAGNLLLASFGGP +AGLTRFFRSAGDTISRLDRNEPDLNNVAPDDPRDTTTPGAMSETVRQILLGDTLKSASRA +QLTAWMVGMKTGDARIRAGLPSGWRVASKTGSGNGGEANEAGIFWPPGRAPVVLSVYYRK +SEGSADQRNAVIAEAARIVA--- +>[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. Ad46 TaxID=989432 RepID=UPI0007AEB34F +-----DTVSQLETEVGGRIGVVLRHTGSDWAV-EHRADERFPMASTFKALLCGAVLSRVD +RGEESLGDLVTYKATELVPYSPVTENHVASGMSVGQLCEATVTMSDNSAANLLLKRVDGP +EGLTRFLRGLGDRVTRLDRNEPAMNEARRGDPRDTTSPSAVLKTLDRLLFEDVLLPSSRA +QLQQWMVDDKVADELIRKHLPKDWCIADKSGAGYNGSRGIIAVLWPETGKPYLAAAYMSG +SDASFKQRNAVIAEIGKAMIE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Halomonas sp. NBT06E8 TaxID=2609667 RepID=A0A644Q7Y5_9GAMM +---ITAELARIEQALDARIGFAAHNLATGQRW-EVNADERFAMSSTFKTLACGALLEQVD +EGQLALETEVSFEESDLVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLVLQALGGP +EAVTAFARSMDDPITRLDRYETELNEATPGDERDTTTPNAMLATLEKLVLGDVLADESRQ +QLEAWMKGNAVADGLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQPPTVAVFYITD +TEASFEERNAAIASLGEVV---- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. UNC279MFTsu5.1 TaxID=1502775 RepID=A0A1I3LCC8_9CAUL +---ISRDIAALEARSGGRLGVAVLDTADGKAF-AHRGDERFALCSTFKALVAGLVLKRVD +QGQERLDRRIRYGRGVLTAHSPATEKHVGEGMTVGALCEATVTLSDNAAANLLLHTFGGP +PALTAFLRGLGDTVTRLDGYEPALNVVRPGEIHDTTSPSAMLASLRALTLGPVLSPASRQ +QLAAWLVGNQTGDKRLRAGLPRGWKVGDKTGSWGDGTTNDIAMIWPPGRPPLLITAYLSR +STLDDNGRNAVIAEVARLAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC333 TaxID=2070368 RepID=A0A2W2FMZ2_9ACTN +----DREFRQLEQRFDARLGIYAIDTGTGRTV-GYRAEERFAYASTYKALAAAEVLDETR +--DAELDRVVRYSADDLVTYSPITEQHVAEGMTLRALADAAVRYSDNTAGNLLLRHLGGP +QRFEKELRKIGDKVTDAARYETELNEGTPGDRRDTSTPRALAGDLRAYAVEDALEPADRG +ILNGWLRGNTTGAALIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +GEKDAGYDDALIAQATEVVIT-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FBX4_9BACT +-----------EDQLGARVVYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIFAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. musacearum NCPPB 4394 TaxID=1094187 RepID=A0A656S262_XANVA +---LRAQWAEIERGTGGRLGISLLDSATGWHL-GQRQDERFPMCSTFKFVLAAAVLQRVD +QGKLMLAQRVKIRASDMLEYAPVTERHIGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRSIGDAQTCSDRHEPDMNRFAAGDPRDTTTPAAMANTLRTLLLGDALRPASRK +QLTDWMINNRTGDDCLRAGLTRDWKIGDKTGSNGIDTRNDIAILWPPKGAPLLLTAYLNG +AKVEDAARDAALKAVAVAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=UPI00040718D2 +--MLRAQWAQIERGTGGRLGINLFDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP +AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRT +QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas hydrothermalis TaxID=115561 RepID=A0A291JV44_9GAMM +---ITAELARIEQALDARIGFAAHDLATGQRW-EVNADERFAMSSTFKTLACGALLEQVD +EGQLALDTEVSFDESALVTYSPVTEQYAGHRMTLFELCDATMTTSDNTAANLILEALGGP +GAITAFARRLDDSVTRLDRFETELNEATPGDERDTTTPNAMLATLETLVLGDVLTPESRQ +QLQDWMKGNAVADGLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQAPTVVVFYLTE +TDASFEARNEAIAALGDVL---- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2L5_9BACT +------AAQQAETELNARVGLVIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEMLSPAAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLLAAIYLTQ +TDASMEQRNAAIAAIGAALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobacter sp. Root1221 TaxID=1736433 RepID=A0A0Q6XR18_9BURK +-----------ETSVGGRLGVAVLDTATGHCS-GHRVDERFPMCSTFKWLAAAVVLQRVD +AGVERLDRALPVAAHDIIDHSPVTVTRVGGTITLGELCEATITVSDNAAANLILAACGDP +AAVTAYARSVGDTVTRLDRNEPSLNEARPGDPRDTTTPAAMAATLNKVVLGDALTRASRE +RLAGWMRGTKTSGDRLRVHLPAGWRLGDKTGSGANGTTNDVGVVWVPGRAPVVVAMYLTE +AGASPAARNAVIAEAGRVVWT-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TSRI0395 TaxID=1703923 RepID=A0A1Q5C3T0_9ACTN +----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRRYG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAEPERA +RLAQWLTANTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +RDADADYDNTLIAKATSAAV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella michiganensis TaxID=1134687 RepID=A0A2J4QBU1_9ENTR +--AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKADLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP +EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRT +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDCGTTNDIAVIWPENHAPLVLVTYFTQ +PQQDAKSR--------------- +>[subseq from] class A beta-lactamase n=1 Tax=Granulicella sp. S190 TaxID=1747226 RepID=UPI00131CB7E3 +---LPALLAQLEHSNSCRLGVAVLDTASGERT-GHRSDERFAMCSTFKMLLAAAVLQRVD +AGHERLNRNLSVPARPLVSHSPVTEEHAGAEMTVSALCDAILTQSDNTAANLLLDTLGGP +GGVTLFARSIDDKITRLDRTETSLNEALPGDPRDTTSPSAMVENLQKLLLGNVISTSSRN +QLIQWMVANTYGDTRLRKTLSANWKAADKTGANGETTTNDIAIFWPPHHPPVLIAAYLTE +CPGSDDKRNTILAEVGRIVV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1D3PD80_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLIKNS +--LEALDQKIRYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Salmonella typhi TaxID=90370 RepID=A0A0E3Z6W4_SALTI +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Belnapia rosea TaxID=938405 RepID=A0A1G6TD82_9PROT +---AADALAALESRQGGRLGVAILDTGTGRAL-AHRGEERFPLCSTFKFLAAGLVLARVD +RGEERLDRRVAYGPEALVPYSPVTGPGAEAGMTMGAICDAAVTLSDNTAGNLMLDSFGGP +AGLTAWMRGLGDPVTRMDRREPELNLVPPGDERDTTTPLAMIGLMRALLLGDALRPASRE +QLAAWLVACRTGDRRLRAGLPAGWRVGDKTGTGPDIPTNDVAVAWPPGRAPILIAAYLLG +ARGSEAERSAVLAEVGRIAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. ICMP 5592 TaxID=2292445 RepID=UPI001294B709 +--DADKLLADLEKRTGGRLGVSVLDTETNISL-GYREAERFALCSSYKALAAGFVLARVD +QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCNAAITLSDNTAGNLLLDSFGGP +AALTAWLRTTGDTETRLDRKEPDVNQAIKDDPRDTTTPDSMLDTIGLLTLGNTLSETSRD +QLSNWLVNNTTGNARLRAGLPKEWKVGDKTGTGENGSYADVAVVWLPDRGPILVVTYVGE +ATAPAKDIEAVFAEVGKIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF10870 +-----HSFVKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF0C34E +-----HSFVKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Modestobacter caceresii TaxID=1522368 RepID=UPI000568B116 +---VGEALTALEGEFDARLGLYAVDTGSGQVV-AHRADERFGYASTHKALSAAAVLDRTT +--DAELDQVVTYTAEDLVTHSPVTEAHVGAGLPLRELAAAAVQHSDNTAANLLFDRLGGP +AGLEQALRDLGDDVTSVDRTETALNTAVPGDVRDTSTPRALATDLQAVLLGDALDPADRD +LLTGWMRDNATGGTLVRAGVPADWQVADKSGGGGHGTRNDIAVVWPPDGAPIVLAVLSSR +DEADAEYSDALIARATDIAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFB3038 +-----HSFVKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CS131 TaxID=2162711 RepID=A0A2T7KA48_9ACTN +------DFKKLEREFDARLGVYAIDTGTGREV-THNDRDRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +GGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAVIRAGVPESWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus telephonicus TaxID=1714840 RepID=A0A3S0JH58_9BACI +---AEETFRQLESQFDARLGVYAIDTETGKST-SYRADERFAFASTYKALAAGAILEQKS +--LNELDEMITYTKDDLVTYSPITEKHVDTGLSLKDIAEAAIRYSDNTAGNLLFNKLGGP +AGFESALRNIGDMVTESDRFEPDLNFIVPGDTRDTSTPRALATSLQTYVISDLLPSEKQA +LIKDWLVGNTTGDTLIRAGVPKDWVVGDKSGAGSYGTRNDIAIVWPPDRDPIVIAILSDR +NIEDATYDDALIAEAAKIVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Halobacillus aidingensis TaxID=240303 RepID=A0A1H0UE07_HALAD +----NRKFSQLESKFDARIGVYAIDTGTGRTV-AYRPDERFAYASTYKALAAGAILQQNS +--ISELNKVITYTSKDLVTYSPITKMHVDTGMTLRELCAAAIRYSDNTAGNLLLQELGGP +DGFEKALKQIGDNVTQPRRYETDLNEAIPGDIRDTSTPRTLATDLQVFTINNVLPSEKRT +ILINWLRTNTTGDKLIRAGVPKIWKVGDKSGAGGYGTRNDIAIVWPPNRAPIVMAILSSR +DKKNVTYNDALIAKAAKVTIK-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=C0LSK3_KLEPN +-----EQITRSESQLAGRVGYVEMDL----LA-AWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD +TPATMAERNQQIARIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. LTSP849 TaxID=1615890 RepID=A0A0D7PUE4_9BRAD +------ELESYERESGGRIGVYAENLATGAKL-IWRADERFVMCSTFKASLAACVLARVD +RGEEQLAATIPYGQADLLDYAPVAKQNLSTGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDSISRLDHNEPELNRSPPGDPHDTTTPAAMANNLRRLVTGEALSQASRA +QLTDWMVNCKTGANRLRGGLPADWKIGDKTGNNGKDASGDIAIVWPKPDRPILIAAYTQG +GTPTAAQIEAVFARIGRMVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces parvus TaxID=66428 RepID=UPI0013BB68F2 +------AFKKLEREFDARLGVYAIDTGTGREV-THNDRARFAYHSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNAAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSNWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGNYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. KC216 TaxID=2530370 RepID=A0A4R4M9S4_9ACTN +--DVTAKLRRLEETRDVRIGAYAVDTATGRFV-AHRADETFPFASTFKAFACGAVLRKAD +SDPGLMDRVIRYKKSDLAAFSPVTEKHVGTGMTVADLCHATITRSDNTAGNLVLKEIGGP +AGLTAFLRSLGDTVTRSDRWEPGLNDWKPGEKRDTTAPRAWAGSLRALTVGDALAPADRD +RLNAWLKATVTGGKRIRAGLPEGWAAGDKTGTGGYGSANDIAIVWPPSRAPLVIAILTTR +PDAGARTDERAIAETARVLTQ-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID7982 TaxID=2706094 RepID=A0A6B3FKI9_9ACTN +------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +EGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALPAPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Massilia dura TaxID=321982 RepID=UPI0012DA8FEE +------GFDAIEYDLDGRLGVAVIDTATGKVA-GNRLDERFPMCSTFKAILAAQALARDA +REPGFIGRRLRYAKTDLVSHSPVTGRHVAGGMTVAELCAATVQHSDNTAANVLMDELGGP +AALTAFARTIGDTAFRLDRRETALNSAIPGDERDTTTPLAMARTLQKLVIGDALPAPQRL +QLKDWLVGNTTGDNRIRAGLQAGWQVGDKTGTGAYGVTNDIGVVFPPDRAPLVVVVFTHQ +RAKDADSRDDIVAAAARAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02130 TaxID=1703934 RepID=A0A1Q5G2W9_9ACTN +------DFQKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Tuberibacillus sp. Marseille-P3662 TaxID=1965358 RepID=UPI000A1C9AD7 +--KTDEKFDQIENEFNARLSVYAIDTGSNQTI-EYRPDERFAFASTYKALAAAIVLQQNT +--MEELKEVITYTKDDLVPYSPITKKHVDTGMALLKLAEAAVRSSDNTAGNLLLKALGGP +DGFEQALRQIGDNVTQADRYEPNLNEFTPGDTRDTSTPKVLATDLQAFAVGDLLSNDDRE +RFTNWLQGNATGDTLIRAGAPKGWEVGDKSGAGNYGTRNDIAVVWPPNREPIVISIMSRH +DTEDAKYDDTLIAQAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Paludifilum halophilum TaxID=1642702 RepID=A0A235B725_9BACL +--AVTDDFAKLEEKFDARLGVFALDTGTNQTV-TYRPDERFAYASTHKALSVGALLQQKS +--IEDLDQKITYTRDDLVNYNPITEKHVDTGMTLKELCDASLRYSDNTAANLIFEQLDGP +RGFKKSLREMGDNVTNPERIEPELNEVKPGETHDTSTPRALATSLQAFTIGEALPTEKRS +LLTDWMKRNTTGSTLIRARVPKDWKVADKSGGAGYGIRNDIGIIWPPKSDPIVLAILSHR +DKKDDEYNDKLIAQATKEVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. CNZ322 TaxID=2572904 RepID=A0A560AQI6_9ACTN +--AADQEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADDRFAYASTWKALAAAEVLDGTT +--DAQLDRVVRYSARDLVAHSPVTEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +AGFESKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALQPADRD +VLIGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPARAPIVLAVLSSR +DKKDASPDDAVIAQATRVVVT-- +>[subseq from] Beta-lactamase n=1 Tax=Aquabacterium sp. SJQ9 TaxID=2493092 RepID=A0A3R8S7K1_9BURK +---WRQRLWALERNSGGRLGVAALDLHTGARL-AWRADERFPMCSTFKLPLAAMVLQRAD +RGQERMDRLLLIDKAALVPHSPITERHVGEVMTMTQLARAAVTVSDNTAANVLLRELGGP +AAFTAFERSLGDATTRLDRYEPDLNDTPPADERDTTTPAGMLAGLQQAVLGDALSPASRE +LLVRWMRETKTGEHRLRHAVPPDWQPGDKTGTGAPGTANDVAVFWPPGRQPVLVTAYLTQ +ATLPAEGCEAVLADVGRLVV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. (strain 170) TaxID=74566 RepID=Q45414_BAC17 +----NQSFVKLEKEYDAKLGIYALDTSANQTV-TYRSDERFAYASTHKALAVGAVLQKKS +--IEDLEQRIKYTSKDLVNYNPITEKYIDTGMTLKELMDASIRYSDNTAQNLILTQLGGP +SGIQKIMREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVENRN +FLIDLMKRTTTGDNLIRAGVPGEWEVPDKTGSGSYGTRNDIAFIWPPNKKPFILAILSNQ +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DBFE121 +--AADHEFRRLEEQFGARLGIYAVDTGSGRTV-EYRADERFAYASTWKALAAAEVLDGTT +--DAQLDRVVRYSPRDLVAHSPVTGKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +AGFESKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALQPADRD +VLIGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DKKDATPDDAVIAQAAEVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF91D04 +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces globisporus C-1027 TaxID=1172567 RepID=A0A0U3MMJ8_STRGL +------DFQKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis subsp. spizizenii (strain TU-B-10) TaxID=1052585 RepID=G4NPW6_BACPT +----NKKFVQLEKKFDARLGVYAIDTGTNNTI-AYRPNERFAYSSTYKVLAAAAVLEKNS +--IEKLNEVIYYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR +FTKDANYNNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces cavourensis TaxID=67258 RepID=UPI000DC64CF1 +---TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS +--LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANILFRELGGP +RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR +DVKDAEPEDALIAEAAEVALEAf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sulphureus TaxID=47758 RepID=UPI000372497A +-qQTTREFAALERKFDAKLGVYALDTGSGKEI-AHRPDTRFAHASTFKALLAGVVLEQTS +--AAGLDERVEYTEKDLPEYSPITERHASDGMTLRELCDAAVRHSDNGAANLLIRHLGGP +AELQKALRASGDRVTHTDRYETELSAAEPGDVRDTSTPRALAGSLRTYAVQDALPAKKRA +MLTDWLKRNTTGDDLIRAGAPKGWKVGDKTGNGGYGTRNDIAVVWPPKSDPIVLAILSKR +DTKNAEHDDALVADAAEVALE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. Leaf13 TaxID=1736211 RepID=A0A0Q6H584_9BACI +----NHDFAKLEEKFDAKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS +-----INQRITYTREDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP +TGFKKALEEIGDNVTNPERFEPDLNEVNPGETHDTSTPRALATSLQAFTLGDTLPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DKKDADYNDKLIAEATEEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus vallismortis TaxID=72361 RepID=UPI000C29F514 +----NEKFVQVEKKFDAKLGVYAINTGTNKTI-SYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEIAEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNNLTPDKRT +ILTDWMRGNATGDELIRAGAPIGWLVGDKSGAGSYGTRNDIAIVWPPHRAPIVVAILSNR +FTEDAHYDNALIAEAAKVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009AE47AC +----NKKFVQLEKKFDARLGVYAIDTGTNNTI-AYRPNERFAYSSTYKVLAAAAVLEKNS +--IEKLNEVIYYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR +FTKDANYNNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=I7AP07_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKXLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAXXRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIA---------- +>[subseq from] Beta-lactamase n=1 Tax=Verrucosispora sediminis TaxID=547162 RepID=A0A1I1J794_9ACTN +-----VDFAPLEREFDARLGVYAIDTGSGSTV-THRADERFAYASTFKALAAGAVLAATS +--TEELDQVVSYSRDDLVTYSPITERHVDTGLSLRAIADAAVRYSDNTAGNLLLKQLGGP +SGFMQALREVGDEVTEPVRWETELNAYVPGERRDTSTPEALATTLRAYAVDDALSPDDRA +LLVDWLKRNTTGDKTIRAGVPEGWAVGDKTGSADHGTRNDIAVIWPPDRAPIVLAVLSDR +AEPDAERDDALLARATELTLD-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A5D4INT7_9ACTN +------AFRKLEREFDARLGVYAVDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYAREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +EGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEC1057 +----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKALQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A1S6R9P0_STRHY +----TGEFKKLERSYDARLGVYAIDTGTGHEV-AYRDGERFGYASTFKALEAGAVLQKVK +--LGGLDRVIKYSKDDLVDNSPVTEKHVDTGMSVGALCDAAVRYSDNAAANLLFDELGGP +KGLDAMLEKMGDDVIQMERREPELSRWVPGSTQDTSTPRAMAKDLRAFVLGDVLGDGERA +QLTKWLRTNTTGDALIRAGVPKDWQVGDKTGSGSYGGRNDIAVVWPPDSAPIVVAIMSNR +ADKDAKSDDKLIADAAHVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Kosakonia cowanii TaxID=208223 RepID=UPI001117CDE8 +-qTLQKKIEMLENKSGGKLGLTVVDTSDGTTY-SWRGDEKFPLCSTSKVMVVAAILKKSE +SNTNLLAKKITINKSDMVNYNPITSKYIDSSMTITELSKAALQYSDNAAMNKLLSYLGGP +RYATQFARTIGDKAYRLDRNEPGLNTAIPGDSRDTTTPSAMAETLNKLILGNALKKEQKA +KLTEWMKGNTTGLNSIKAGLPAEWIVADKTGSGDYGTTNDVAVIWPKNHAPVILTTYFTQ +PEKDASARKDVLASAAKLIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Dyella sp. 4MSK11 TaxID=1927960 RepID=A0A370WVG4_9GAMM +--DVRAKLAALERKHGGRLGVAVLDTGSGRSV-GHRADERFMMCSTFKMLLAAATLDRVD +RGAEQLDRHLIFGKDAVLSYAPVTQHHVGLPMSIADLCKAAVSLSDNTAANVLLANLGGP +AAVTAYARQLGDTMTRLDRNEPELNRPSPDHVSDTTTPASMLNNLRTLVLGHVLRDESRK +LLTEWLRETTTGKNRLQAGLPAGWVTGDKTGSGYD-ATNDVAIMWPPQRKPLLVSAYYSA +ANLDDDARSAVLADVGRIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. JS01 TaxID=1525753 RepID=A0A087K7P2_9ACTN +------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase SME-3 n=1 Tax=Serratia marcescens TaxID=615 RepID=Q6PRG8_SERMA +--AAAKQIKKLEEDFDGRIGVFAIDTGSGNTF-GYRSDERFPLCSSFKGFLAAAVLERVQ +QKKLDINQKVKYESRDLEYYSPITTKYKGSGMTLGDMASAALQYSDNGATNIIMERLGGP +EGMTKFMRSIGDNEFRLDRWELELNTAIPGDKRDTSTPKAVANSLNKLALGNVLNAKVKA +IYQNWLKGNTTGDARIRASVPADWVVGDKTGSCGYGTANDYAVIWPKNRAPLIVSIYTTR +KSKDDKHSDKTIAEASRIAIQ-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. AC27/96 TaxID=1841653 RepID=A0A1B9SDG5_9RHIZ +--DVDKQLADLERKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD +QGVEKLDRRVAYGKDKVVTYSPETEKHAGTDMTIAELCGAAITLSDNTAGNLLLESFGGP +AALTAWLRTTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD +QLVNWLVGNTTGNNRLRAGLTKEWKVGDKTGTGNNGSYADVAVIWPPERGPILVTTFVAE +GTAPAKDIEVVFAEVGKIVV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B1FG53_BACCE +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNP +--INKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNLLFNKIGGP +KGYEKALRQIGDRVTMAERFETELNEATPGEIRDTSTAKTLATNLKDFTVGNALPADKRK +ILTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGNYGTRNDIAIVWPPNRAPIIIAILSSR +DEKEATYNNELIAQATEVVTN-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) TaxID=288000 RepID=A5EJY1_BRASB +--DLQQTIAGIEADCGGRLGVALLDSASGALS-GHRLDERFPMCSTFKALLAAAILTKVD +AGAEQLSRRIPIAQADILSYAPVTKQHVGTSLSVGELCEATVTLSDNTAANLLLATLDGP +AGLTRTIRGFGDAITRLDRIEPGLNESIPGDPRDTTTPAAMAQTLAKLTVANTLSAASRD +VMNGWLIGCKTGAAKLRAGLPAEWRVGDKTGAGDHGSSNDVAVIWPAGRGPVIVTSYLTE +TKASDDRRNAAHAAVGRAVAA-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1JQZ2_9ZZZZ +--ETLVKVKDAEDQLGARVGYIELDLNSSKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMD----------------- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001118893C +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Phaeobacter piscinae TaxID=1580596 RepID=A0A291G7G1_9RHOB +-qDLQNTVADWEERLNARIGVVLRDTSSDWEI-SMRAEERFPMSSTFKSLLCGAVLSRVD +AGQEDLDRRVTYAEGDLVAYSPVTEQHLDNGLTVGELCEATVTLSDNTAGNLLLDTVGGP +EGLTNFLRDIGDQTTRLDRWETALNEAAPGDPRDTSTPSAILNTLETLLLGDVLEPATAA +QLRQWMIDDQVADALIRAHLPEGWVIGDKTGAGGNGSRAIIAFIEPEADVNYFAAIYLTE +SDADFALRNQVVSEIGQAMI--- +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sanxanigenens TaxID=397260 RepID=W0ADZ5_9SPHN +----TEQMQAIERESGGRLGVALIDTGNGRRF-AWRGEERFPLCSTFKLLLAGATLARVD +SGEERLDRRVAVTEKDIIAHSPVTGEAVGGTLSVDELCAATLTTSDNAAANLLLAPLGGP +EKLTAWLRAIGDPVTRLDRPEPFLNESKEGDPRDTTSPVAIAEDLERLVVGTALSAASRT +RLARWLEANQTGDNRIRAGAPKGWRIGDKTGTGERGATNDVAILWPPSGKPLLLSTYLVG +SSAEQAAREKVLASAARSAL--- +>[subseq from] Beta-lactamase n=1 Tax=Frateuria sp. Soil773 TaxID=1736407 RepID=A0A0Q9PNU4_9GAMM +----AARLAALERRHGGRLGVSILDTGNGRRA-SHRGGERFLMCSTFKLLAVAAVLMRVD +HGEERMDRRIVFGKDVLLSYAPVARRHVGAPMSVEELCAAAITLSDNTAANLLLASMGGP +AAVTALARRLGDGVTRLDRNEPMLNVGSPGDLRDTTTPDAMLATMQKLLLSHALADASRE +RLLAWLRACTTGFEKLRAGVPPGWTVGDKTGSGPKGESNDVAILVPPGRKPLLVAAYYAD +SPADDAARNAVLAEVGRIAA--- +>[subseq from] Beta-lactamase n=3 Tax=Streptomyces TaxID=1883 RepID=W9G608_STRFL +------DFKKLEREFDARLGVYAIDTGTGREV-THNDRARFAFNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +RGLDASLERLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPEDRLIAEAASVVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-475 TaxID=1463910 RepID=UPI000A5C4032 +---VTARLRELERKHTARLGVYGRNLRTGRTV-AYRADERFPMASVFKTLAAAAVLRDLD +REGEFLARRIHYTQEYVTKYSPVTEDHVATGMTVGELCDATIRFSDNTAGNLLLEELGGP +TAVTRFSRSVGDRITRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGSALEPRDRA +RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNNDVGITWPPDGPPIVMSVLTTQ +PEEDAPADNPLVAGAAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces cavourensis TaxID=67258 RepID=UPI000E0DEBF4 +---TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS +--LPQMERLVRYGQEEIISHSPITEKHVDTGMTLRELCDATIRYSDNAAANILFRELGGP +RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPADKRA +LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR +DVKDAEPEDALIAEAAEVALEAf +>[subseq from] Beta-lactamase n=1 Tax=Ramlibacter henchirensis TaxID=204072 RepID=A0A4Z0C866_9BURK +------KWTALEMLSGGRLGVAVLQ-ADGRID-GHRLDERFPMCSTFKWLAAACVLRRVD +AGQEQLDRTIPFGADALLAHSPVTQEHAGNGMTLAQLCAATIAVSDNAAANLILSTFGGP +AGLTTYARSLGDTVTRLDRWEPDLNEATPGDPRDTTSPRAMAGLLHATLVGNALSSASRE +QLGRWMEATRTNEKRLRADLPSGWRMGSKTGTGARGTTNDVGIFWPPGRPPVVVVAYLTQ +TDAPEADRNAAVAEVARRMV--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium endolithicum TaxID=1191678 RepID=UPI00115A1DCC +--TVAETAAEVEADLGGRVGVLLQQYGEAPAA-TYRADERFPLASTFKALACGAALSRVD +AGEQDLEAIIKYGADDIVTYSPITEKHVGVGMTLGDLCHATITLSDNTAGNLVLDSVGGP +SGFTAFMRKIGDEVTRLDRWEPELNEALPDDPRDTTTPRAVVTTLERLLLGDVLLPASRR +QLEEWMIADQVADKLIRASLPKGWTIGDKTGAGERGSRSIIAIIRPPQGKPWLAGIYLTG +SDADMDKRNEAVAMVGAAIVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus sp. AG TaxID=2681969 RepID=UPI0012EB8884 +-qTIDNHFAQLEKEFDAKLGVYAIDTGSGKII-DYQADERFAFTSTVKALAVGAVLQQNT +--MEELNETVTYTKDDLVTYSPITEKHVDSGMTLLELSEAAIRYSDNTAGNLLFNELGGP +DGLEKAMRDIGDTVLHSNRTEPNLNEAQPGDIRDTSTPKALVTSLQAFALDDLLSKPKQD +MLLEWLQTNTTGDTLIRAGVPEEWTVGDKSGAGGYGTRNDIAIVWPPDQEPIVIAILSSR +DTEDASYNDDLIKQATEITVD-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL25I1N1 TaxID=1938804 RepID=A0A2T0QSZ1_9BURK +--AVRRRLVEIEAASGGRLGVSIVDTMSGLHA-GLRTDERFPMCSTFKMLMAGAVLARTD +RGEEDLQRRVVFSQSDVVSNSPATSKHTRELMSIAELCKAAITLSDNAAANLLLATFGGP +AGLTAFARSLGDGVTRLDRIEPMLNEGTPGDLRDTTTPNAMLGNLRELLLGERLSSSSRA +QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDIAILWPPGRGPVLVTVYLTE +TDGNAARSNAAIADVGALVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Tu 3180 TaxID=2682611 RepID=UPI00135B9A70 +------SLAALEREYGARVGVYAVATDTGATV-VHRADERFALCSVFKSLAAAAVLDRDP +--LDRLDQRITYTRDDLAAHSPVAEKHVATGMTVRHLCDAAVRYSDNTAANLLLRHLGGP +RALTTYLRGLGDRVSRLDHYEPELNTNPPGDPHDTTTPRAVAADHRALVLGDALPAAKRD +LLKDWLVRNTTGDRRIRAGAPRGWTVGDKTGTAEWGRANDVAVLWPPRAAPLVLAVLTDR +PDRGAAPSEPLIAEATRRT---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces acidiscabies TaxID=42234 RepID=A0A117E9V7_9ACTN +-aATRDVFAGLEQEYAARLGVFAHDTATGRTL-THRADERFPMCSVFKAPAAAAVLREGV +----DLTRRIHYTQQELTDYAPVTEKHLDTGMTVEELCAAAVSHSDNAAANFLLRELGGP +TAITRFARSLGDSVTRLDRWEPDLNSAEPWRKTDTTTPHAIARTYAKFLLGDVLPPADRT +RLTSWMVANSTNVTRFRAGLPADWILADKTGGGSYGVANDVGVVWPPGRAPLVIAVLTTT +YAAEGPSKNELVARAAELVAA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL WC-3605 TaxID=1609103 RepID=A0A0X3XGU7_9ACTN +--DVRARLRELERGHGARLGVFAHNVATGRTV-AHRADERFPVCSLFKPLAVAAVLRDLD +RDGEVLARRIHYTEADLVANSDVTRAHLETGMTVAELADAAIRFSDNTAGNLLLRQIGGP +TAVTRFARSLGDRVTRLDRWETELNSAEPWRVTDTTSPRAIGRDYARLVLGDALGARDRA +RLTHWLLHNTTSANRFRAALPPPWTVADKTGGGSYGANNDAGIVWTEAGVPLVLAVMTTR +PEQDAAYDHALIVEATRLVAD-- +>[subseq from] Beta-lactamase Toho-1 n=1 Tax=Legionella clemsonensis TaxID=1867846 RepID=A0A222P2W1_9GAMM +---IEKKFEVLEASMNGRIGVFAINTANNQHI-QYRADERFPIQSTFKVMAVSAILKQSM +TDKHLLQQKMTYTKKDLVFWSPITEKHLASGMTISELCSAAIMYSDNTATNLIVKKLGGP +NAVTAFARSIKDSTFRVDNWEPELNSN-PNNLLDTSTPIAMEKSLQKLTLGNTLALPQRE +QLVTWMKNNTTGDARIRAGVPKRWIVADKTGSGGYGISNDIGIIWPPSCAPIVVTIYSVH +NEKATTPRDNVIASATRLIIKEf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A1B1L1C3_BACTU +----NQSFAKLEKEYVAKLGIYAFDTDTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. AC87j1 TaxID=2055894 RepID=A0A2S6MNW8_9BRAD +------EFETYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIAYGKADLLDYAPVAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP +ATLTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALSPASRA +LLTDWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVVWPKPGTPILIAAYTQG +GTPNAAQIEAAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A1W0D810_9NEIS +---TARQLAELERNAGGRIGVFAQEVDSGRSL-AYRANDRFPMCSTFKLLLVGALLQRSA +TQPDLLYRHVSYRREQLIDYSPIAEQYVEQGMSVKDLCDAAMRFSDNTAANLLLEELGGP +QEVNRFARSLGDGLTRLDRIEPELNRAEPGDPRDTTTPAAMTANLHALLFSPLLPERQRG +LLNDWLLGNTTGNLRIRAGLPAEWRVGDKTGSGGHGAANDVAVAWRPGKSPLLLSVFYWG +SPAMMDERNAVIAAVARVAAAEf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. DH-12 TaxID=2072509 RepID=A0A2K2RJD5_9ACTN +------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP +--GARLGERIPYGTADLVPHSPVTEKHTGKGMTLRELCDAAVRYSDNTAANLMLRDIGGP +RGLTAYARRLGDRATRLDHTEPELNSNPPGDPRDTTTPRAIAGDYRALVLGDALPAAGRA +LLTDWLVRNTTGDRRVRAGAPRGWRVGDKTGGGEWGRANDVAVLWPGGRSPLVLAVLTER +PDRAASPSDELVAEAARRVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. WSM3864 TaxID=2029404 RepID=A0A2A3CKI5_9RHIZ +---ATKAVEALESRNGGRLGVMVLGTGTDAAI-EYRADELFPITSTFKFLAAAGVLKAVD +DGKARLDDRIVYAASDVEPYSPVTKEHSGEGMTLEDVCAAAVVWSDNTAGNLLLRVLGGP +QGLTRFARTLGDDVTRLDRTEPTLNTAIPGDKRDTTSPRALLGDARRILLGDALSPASRK +RIEAWLIEDKVGGARIRAGLPAAWGIGDKTGSGDNGTTNTVALLWPPNGAPILAAVYYTG +STAPRASREAVHADVARIIVETf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SS07 TaxID=2015315 RepID=UPI000B5C9B4B +------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPDLSRWVPGEKRDTSTPRALAGDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2B4XFI2_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-TYHSDDRFAFASTSKSLAVGALLIKNS +--LEALDQKIRYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinoplanes italicus TaxID=113567 RepID=A0A2T0K372_9ACTN +--DTARAFDGLERRFDARLGVYALDTATGRTV-THRADERFAHASTFKALQAGAVLRRAT +--DADLRKVVKYRRADLLAHAPITSKHVATGMSLDDLLAASVRYSDNTAANLLFEHLGGP +EALERELRALGDRTTSVDRIEPHLNEAEPGDTRDTSTARALGTTLHTLVLGDALPTARRE +RLTAWLRGNTTGDPYIRAGVPPGWQVGDKTGTGGHGTRNDIAIVWPPAGAPLVIAILSDK +GERDARPADTLIAEATETVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sagamiensis TaxID=47875 RepID=A0A562WBA8_9ACTN +-------FGALEARYGARLGVYAVDAGSGATV-VHRADERFAYASTFKALAAAALLDATT +--AQELDRVVRYTRADLLPHAPVTGRHVGTGMSLRDLAEAAVRHSDNTAANLILAELGGP +AGFAGHLRALGDRTTKPTRTEPALNEATPGDDRDTSTPRALATDLRAYVLGDALDAEDRA +LLTDWLRRNTTGGGLIRAGVPAGWLVGDKTGTGGYGTRNDIAVLWPPGRAPIVLAVLSSR +DAEDADHDDALIAEATRVTLD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces toyocaensis TaxID=55952 RepID=A0A081XRD0_STRTO +-----DSFKELERKHGARLGVYAVNTGDGREV-AFNADERFAYASTFKAFAAAAVLRKYS +--LSGMDKVIKYSRNDLIDHSPVTEKHVDSGMTLRDLCDAAVRYSDNTAANLLFDALGGP +QGLAAALAETGDTTTQVVRREPELNQWSPGATQDTTTPRAWAADLRAFVLGDALGKDERE +QLTQWLRTNTTGDELIRAGVPKGWDVGDKTGGGGYAVRNDIAVVWPPDAAPIIMAIMSNR +GAEDAEYDNRLIAEAASVVTK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1C4CSL0_BACCE +-----HSCVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSITNPERFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGNNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH +AKEDAKYEDKLIADASKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=[Brevibacterium] frigoritolerans TaxID=450367 RepID=UPI0009FD87C9 +--ATIKKFEQLEKEYDAKLGVYAIDTGTKETV-EFHENERFAFTSTHKALAVGALLHQKS +--IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP +AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DEKEADYNDELIAEATEEVIK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A2L1J0T7_ACIBA +---------DAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQXQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATM------------------ +>[subseq from] class A beta-lactamase n=1 Tax=Halobacillus hunanensis TaxID=578214 RepID=UPI0009A69854 +--KTDEKFSKLENEFDAQLGVYALDTGTDQTI-EYQSEERFAFASTYKALAAAIVLQQKS +--KDELEEVITYTEDDLVTYSPVTKKHVDTGMTLLKLSEAAVRTSDNTGGNLLFKTLGGP +NEFEQALRQIGDNVTQADRIEPELNEFTPGDTRDTSTPKALATSLKEFAVGDLLSNDKRE +LFTDWLKGNATGDALIRAGAPEGWVVGDKSGAASYGTRNDIAVVWPPNREPIVIAIMSHR +DQENAQYNDELIAQAAEIALN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=H1AFJ2_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVRELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYSAG +NTPGEHG---------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces megasporus TaxID=44060 RepID=UPI0004E20BC8 +------PLRALERKHDARLGVYALATGTGKAI-AHRADERFAFCSTFKTLAVAAVLHRNP +--LSHLDEHVTYTWDDIKSISPITRQNVAKGMTVGQLCDAAIRHSDGTAANLLLRDLGGP +ERLTAYLRKLGDTVSRLDRYEPELHQARPGDPRDTTSPRAIAADYRTVVLGDALAADKRA +LLTDLLVRNTTGGNRIRAGLPKGWRVADKTGTGNYGRANDIAVVWPPRSAPLVMAIMSER +SEQEDRPSEALIAEAAEHIA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB03238 TaxID=1907777 RepID=A0A1X1N6Y6_9ACTN +------QLRALERRHGARLGAVARNTVTGATV-LYRADERFPMCSTFKTLAAAAVLRDLD +RHGEVLAKRVRYTRDDLVENSDKAEEYLATGMTVAELCWAAICFSDNTAANLLLRELGGP +AAVTRFCRSLGDGVTRLDRWEPQLNTAEPWRVEDTTTPAAIAGTYERLVLGTALNRPDRE +RLTGWLLANTTSTYRFRAGLPADWRLADKTGGGAYGTNNDVGVAWTPDGAPVVLAVLTTK +PEQDAPADNPLVRDTASVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus sp. Mc5Re-14 TaxID=1030529 RepID=UPI000B882E22 +-----VVFKQLEIKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS +--NDELGKVIKFAKDDLVTYSPITEKHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP +EGFEKAMRDNGDTVVMANRYETELNEAIPGDHRDTSTPNALANSLKVLTFDDSMPNDKQE +LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR +DTKDAEYNNALIAEAAKAAFK-- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00062D1C9A +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTC +QT--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Paracoccus tibetensis TaxID=336292 RepID=A0A1G5K8V8_9RHOB +--TIEDAARAIEAELGGRVGVALRRQGSPAEFfGYRSDERFPLSSTFKAPLCGAILTLVD +AGEDQLDRVIGYTSADLVTYSPVTEARVDSGMSVGELCEATITLSDNTAGNLLLQRVGGP +EGFTEYLRAIGDETTRLDRWETDLNEGTPGDPRDTTTPEAMVATLEKLLFGEILSESSRA +QLNAWMEADQVADELLRASLPEGWIIGDKTGAGGHGSRSIIAVIRRPHDTPWLAAVYLTG +NEADMPTRNRAIARIGAAMVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Niveispirillum irakense TaxID=34011 RepID=UPI00049032F7 +--AMKADIAALEKKAGGRLGVALLDTATGAAM-DWRGGERFAMCSTFKFLASSFILSRVD +AGKERLDRAVPVTKADLVPWSPLSEPHIGGTMTMAALCEAAMIQSDNMAANLLLDQSGGP +AALTAYLRHLGDQTTRLDRKEPKMNNVPENDPRDTTTPLSMLGLMRTILLGDALSAASRE +RLTGWMINNKTGDTRLRAGLPGGWRIGDKTGGSDE-ASNDIAILWPPGGGPLLLASYYIN +GKVPTAQRNAVHADVARLVAGAw +>[subseq from] Beta-lactamase protein n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=H9BW95_VIBAL +-dTLTQQVAQLESQSGGRLGVAVLDTQNNHQW-QYRGDERFPMMSTFKALMCASALDLAD +QNKLSLNDTTTIKESDLVTWSPVTEKLIGQDMTIQQACEATMLMSDNTAANIVLHQIGGP +QQVTQFVRTLDDKVTRLDRYEPELNQATPGDKRDTTSPHAMVTSLNTILLQDGLSEKNQQ +TLLTWMKNNKISDSLIRSILPQGWSIADRTGAGEQGSRAINALVWNEQHKPIIISLYLTH +TELDIAQRNQTLNQVAKLVLEHf +>[subseq from] Class A beta-lactamase n=1 Tax=Janthinobacterium sp. TaxID=1871054 RepID=A0A349L0P2_9BURK +----QSRFAELERGTGGRLGIAAIDTGSGRQI-DYRSSERFPLCSTCKIMVTSAILSHSA +NDEALLQRRLKYPKSELVANSPVTEKNHDKGMTVAELCAAAMQYSDNTATNLLLKVLGGP +AAVTAYARTIGDSVFRLDRRETMLNTAIPGDERDTSTPLAMMLSLRKLGLGEALGPAQQE +RLQQWMLGCTTGAEKIRAGVAANWKVGDKSGGGAFGTTNDVALLWPPGREPIVLAVYFTQ +PEKDAKTRNDVVAAATKLS---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A4R4BIR3_BACTU +----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTAMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIADTTKIALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Agrobacterium rhizogenes TaxID=359 RepID=UPI00064557F8 +-eDADKQLADLEKKTGGRLGVSILDTETNISL-GYREAERFALCSSYKALAAGFVLARVD +QGVEKLDRRVTYGKDVVVTYSPETEKHADTDMTIAELCSAAVTLSDNTAGNLLLDSFGGP +AALTAWLRTTGDTETRLDRKEPDVNQAVKDDPRDTTTPDSMLDTIGLLTLGNTLSDTSRD +QLSSWLVNNTTGNARLRAGLPKEWKVGDKTGTGENGSYADVAVIWPPERGPILVVTYVGE +ATAPAKDIEAVFAEVGKIVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sphingomonas sp. LLH-Irr-2 TaxID=1564862 RepID=A0A097SRQ8_9SPHN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIVDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMD----------------- +>[subseq from] Beta-lactamase n=1 Tax=Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) TaxID=369723 RepID=A4X4X3_SALTO +--DLDHEFRQLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYASTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIAEAAVRYSDNTAGNLLLDHLGGP +ERFEKELKGIGDTVTDAARYETDLNEATPGDPRDTSTARALTEDLREYAVDDALEPGDRD +TLNGWLRGNTTGGELIRAGVPDGWVVGDKSGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI000B4566A9 +----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +NGFEKSLKQIGDHVTKSNRFETELNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Nocardia TaxID=2637762 RepID=UPI00135828DA +------SFAEMETTHSARLGVYAIDTGTGRTV-VHRDGERFPIASTFKGLACGALLRDHP +LATGYFDQVIHYSRSELVLNSPVTEKHVDTGMTVAELCDATITLSDNTAGNLLLKLLGGP +EGFTAFLRSIGDTVSRLDRWEPELNTAIPGDERDTTTAAALATDYRNLVLGDILAEPERA +QLKSWLVAAKTGDARIRAALPADWTVGDKTGSPAYGGALDVAIAWPPGRAPLVIAVLSTK +FEQNAEADNPLVAEAARAAV--- +>[subseq from] Beta-lactamase n=1 Tax=Kosakonia cowanii TaxID=208223 RepID=A0A410KEN5_9ENTR +-qTLQKKIEMLENKSGGKLGLTVVNTSDGTTY-SWRGDEKFPLCSTSKVMVVAAILKKSE +SNTNLLAKKITINKSDMVNYNPITSKYIDSSMTITELSKAALQYSDNAAMNKLLSYLGGP +RYATQFARTIGDKAYRLDRNEPGLNTAIPGDSRDTTTPSAMAETLNKLILGNALKKEQKA +KLTEWMKGNTTGLNSIKAGLPAEWTVADKTGSGDYGTTNDVAVIWPKNHAPVILTTYFTQ +PEKDASARKDVLASAAKLIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI000B927801 +----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +NGFEKSLKQIGDHVTKSNRFETELNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T322_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQEISLDALCGATMRTSDNTAANKVLEALGGP +DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA +ILTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLLAAIYLTQ +SDASMEQRNAAIAAIGTALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CEV 2-1 TaxID=2485153 RepID=A0A3N1TKG8_9ACTN +--RTEQAFRTLERKFDARLGVYALDTGNGRTV-THRPDERFAYASTCKALLAGAVLDKNS +--LRQMDRLVRYGRDDLVSASPITEQHVATGLTLRELCDAAIRYSDNAAANLLFHELGSP +RALQDALRALGDNVTRCDRYETALSAATPGDLRDTSTPRALATDLRAYVLGTTLPADKRA +VLTDWLRRNTTGDNTIRAGAPDTWQVGDKTGTGGYGTRNDIAIVWPPGAAPIALAVLSRR +DTKDAERDDALIARAAKVAL--- +>[subseq from] Beta-lactamase (Penicillinase) n=1 Tax=Xenorhabdus bovienii str. puntauvense TaxID=1398201 RepID=A0A077NHD0_XENBV +-nQITNQLSALEKNANGRLGVVLIDTADHSII-TYRGHERFPLCSTSKMMAVSALLKKSE +TDKDLLNQRIHYQQSDIVEYSPITEKHLKDGMTLAELSAATIQYSDNTAMNLLLGQLGGA +HSVTRFARSIGDNAFRLDRKEPELNMVTPGDERDTTTPQAMADSLYKLALGNTLAATQRT +QLVEWLKGNTTGGTSIRAGVPDNWIVGDKTGRCDYGSTNDIAVIWPDDKAPLILVTYFTQ +PSKDAKAHNDVLAATARIMTQ-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Go-475 TaxID=2072505 RepID=A0A2Z5JV49_9ACTN +----TARLRKLEQEHTARLGVYARNLRTGRTV-AYRADELFPMASVFKTLAAAAVLRDLD +RDGEFLARRVHYTQEYVTDHSPVTEDHVATGMTVAELCDATIRFSDNTAGNLLLKELGGP +TAITRFARSVGDGVTRLDRWEPELNSAEPWRVTDTTSPRAIGRTYARLVLGDALQPRDRA +RLTDWLLRNTTSAEKFRKALPADWLIADKTGGGRYGGNHDVGLTWPPDGPPIVMSVLTTQ +PEEDAPADNPLVAGTAQLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0013E322C2 +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNARIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQSLPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus sp. FJAT-22058 TaxID=1581037 RepID=A0A0M1NVA7_9BACI +---TIKKFEQLEKEYDARLGVYAIDTGTKETV-EFHENERFAFTSTHKALAVGALLQQKS +--IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP +AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DEKEADYNDELIAEATEEVIK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02115 TaxID=1703939 RepID=A0A1Q5IAB4_9ACTN +----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRRYG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAEDLQAFVLGDALAKPERA +RLAQWLTANTTGGELIRAGVPKGWAVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +TDADADYDNTLIAKATSAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia asiatica TaxID=209252 RepID=UPI0002E10915 +-----ASLDAVEARYGAQVGLFAVDTGTGATV-THRADERFPFLSTFKALAAAALLHAHP +LDTGYFDRVIRFHEADLVEHSPVTSAAVADGMTLAQVAEAAITRSDNTAGNLLLRELGGP +EAFTAFLRRLGDPTSRLDRWETELNTAIPGDERDTTTPAALAADYRAVVLGDALGARERE +QLIAWLKANTTGAERIRAGLPPAWVTGDKTGTGSYGSANDVAIVWPEGGAPLVIAIQSRK +SDEAAEVNNALLAEVTKAVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces cavourensis TaxID=67258 RepID=A0A543VZ70_9ACTN +---TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS +--LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANILFRELGGP +RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALAADLRAYALGPALPAEKRA +LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR +DVKDAEPEDALIAEAAEVALEAf +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia kururiensis TaxID=984307 RepID=UPI0003499DBE +--SVRDALAALERTSGGRLGVCAIPTCKPREI-RYRADERFPFCSTFKVVLAAAILARSL +DVPDLMQRRIRYTKHDLAHYSPVSSKHVKDGMTVAELCQAAIQYSDNTAANQLMKVLGGP +QAVTAYAHATGNAAFRLDRWETELNTAIPGDLRDTSTPAAMARTLQTLTVEQALPSAQRD +QLVTWLRGNTTGAHRIRAGVPADWQVGDKTGTGDYGTANDLAILWPPGRAPVMLAVYFTQ +REPKAKARDDVIAAAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=unknown TaxID=N/A RepID=UPI00143E657A +hrDTRARLRELEAGHGARIGAFAYNLRTKATV-RHRAAERFPICSVFKTLAAAAVLRDLD +RHGETLARRIHYTVADLAGYSPKTGEHLADGMTVEELCDAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PARDAAADSPLVAATASVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BFB51F7 +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPENKRA +LLTDWMKRNTTGDALIRASVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=2 Tax=Halobacillus karajensis TaxID=195088 RepID=UPI0008A76C23 +---ASGKFSQLENEYNARLGVYAIDTGSNQTF-GYRPEERFAFASTYKALAAAIVLQQST +--MNELKEVITYTEDDLVSYSPITEKHVDTGMNLLELAEAAVRTSDNTAGNLLFKVLGGP +DGFEQALRQIGDNTTQSERYEPDLNEFTPGDNRDTSTPKALTTDLQAFAVGDLLSDDERE +RFTNWLQGNATGDTLIRAGAPEGWKVGDKSGAGSYGTRNDIAVVWPPNREPIIISIMSRH +YTEEAKYDDALIAQAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. PBH53 TaxID=1577075 RepID=A0A0H4CAB5_9ACTN +----RAELAELERRYGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDRA +-GCAPLDRVVHYPPHDTLLNSPRTAENVATGMTVADLCAAAIQYSDNAAGNLLLREVGGP +AGLTRFYRSLGDEVSRLDRWEPELNAAIPGDARDTTTPEAIAESLERLTLGRALAGADRE +RFVGWLKGNRTSDERFRKGLPKDWTVADKTGTGDYATANDIGVAWTTRGTPVVLAVLSSK +STPDAPVDQALIADAAAVVAR-- +>[subseq from] Beta-lactamase n=2 Tax=Achromobacter sp. SLBN-14 TaxID=1072374 RepID=A0A542KGX9_9ACTN +--ATTGRLTELEREHGARLGVFARNLRTRHTV-SHRADERFPICSVFKTLAAAAVLRDLD +RHGEVLSRRIHYTRDDLVDGAPVTDEHLAHGMTIAELCDAAVRYSDNSAGNFLLRELGGP +TAITRFARSLGDPVTRLDRWEPELNSAEPGRRTDTTSPRAIGRTNARLLLGDALNRTDRA +LLTHWLLNNTTGGARIRAGVPGTWTVAEKTGSGAYGTTNDVGVARTPDGAPIVLSVLSTR +TDRDAAWDNTLIASTAGVVAD-- +>[subseq from] Beta-lactamase n=2 Tax=Consotaella salsifontis TaxID=1365950 RepID=A0A1T4SYN8_9RHIZ +---IATAVAEVERTLDARVGVAVLDTGTGHHW-SHRGAERFPMASTSKAFACATLLKEVD +AGRKSLDETVAVEKDDILSYAPVTKDKVGEKMSLGALCEAATGQSDNTAINLALEAIGGP +AKVTAFIREIGDTETRLDRTEPELNEGTPGDPRDTTTPEAAVASLKALVLGDALSEKSRA +QLETWLENDKVAGPLLRASIPTGWRIADRSGAGGHGTRGIVATIWPPKRSPVVVAVYLTE +TDADMDKRNAAIAAIGSALVK-- +>[subseq from] Beta-lactamase (Penicillinase) n=1 Tax=Xenorhabdus bovienii (strain SS-2004) TaxID=406818 RepID=D3V277_XENBS +-nQITNQLSALEKNANGRLGVVLIDTADHSTI-TYRAHERFPLCSTSKMMAVSALLKKSE +TNEGLLNQRIHYQQSDIVEYSPITEKHLKDGMTLAKLSAATIQYSDNTAMNLLIDQLGGT +HDVTRFARSIGDNEFRLDRKEPELNMVTPDDERDTTTPQAMADSLYKLALGNTLAATQRA +QLVEWLKGNTTGGASIRAGVPDNWIVGDKTGRCDYGSTNDIAVIWPDNKAPLILVTYFTQ +PNKDAEAHPDVLAAAARIMTQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEE51A5 +----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGLEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI000417B3F0 +--DLDHEFRQLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYASTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAVAEAAVRYSDNTAGNLLLDHLGGP +ERFEKELKGIGDTVTDAARYETDLNEATPGDPRDTSTARALTEDLREYAVDDALEPGDRD +TLNGWLRGNTTGGELIRAGVPDGWVVGDKSGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] Beta-lactamase n=4 Tax=Salmonella enterica I TaxID=59201 RepID=I1W5J9_SALIN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTDG +ES--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces violaceusniger TaxID=68280 RepID=A0A0X3WPI7_STRVO +-----GEFKKLERSYDARLGVYAIDTGTGHEV-AYRDGERFGYASTFKALEAGAVLQKVK +--LGGLDRVITYSKDDLIDNSPVTEKHVDTGMSLAALCDAAVRYSDNTAANLLFDQLGGP +TGLDAMLEKMGDDVIQMERREPELSRWVPGSTRDTSTPRAMAEDLRAFVLGDVLGDGERA +QLTKWLRTNTTGDALIRAGVPKNWQVGDKTGTGSYGGRNDIAVVWPPDSAPIVMAIMSNR +GDKDATSDDKLIADAAHVVADQ- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sagamiensis TaxID=47875 RepID=UPI00119E8E65 +-------FGALEARYGARLGVYAVDAGSGATV-VHRADERFAYASTFKALAAAALLDATT +--AQELDRVVRYTRADLLPHAPVTGRHVGTGMSLRDLAEAAVRHSDNTAANLILAELGGP +AGFAGHLRALGDRTTKPTRTEPALNEATPGDDRDTSTPRALATDLRAYVLGDALDAEDRA +LLTDWLRRNTTGGGLIRAGVPAGWLVGDKTGTGGYGTRNDIAVLWPPGRAPIVLAVLSSR +DAEDADHDDALIAEATRVTLD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T218_9BACT +------AAQQAETELDARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQEISLAALCGATMRTSDNTAANKVLEALGGP +DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLLAAIYLTQ +SDASMEQRNAAIAAIGTALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas lenta TaxID=1141887 RepID=A0A2A2SED3_9SPHN +---------LLEREAQGRLGLAILDTGTGARF-SHRADERFPMCSTFKLPLAAAVLAEVD +RGRERLDRRIAIAASDIVAHSPFAKPRVGGATTVAELCEATTTESDNAAANLLLPAVGGP +AGLTRFMRALDGGVSRLDRLEPVINESLPGDPRDTTSPAAMLAMVRRFALGDALSAASRE +RLVGWMIANKTGGRRLRAGLPADWRVGDKTGAGERGSDNDVAILWPPNRRPILVASYLTQ +TPLPFERTNAVHARLARLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. FJL06 TaxID=2153365 RepID=A0A3N7E2E1_9BURK +--TWNETLAGIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD +QGRERLDARVHYAATDVVAYSPVSGPRAGNGLTVGELCAATVSLSDNTAANLLLARHGGP +AGVTAFVRSLGDTATRLDRTEPTLNEAKVGDPRDTTTPLAMLHTLHKLVLGDVLSPTSRA +WLQRWLVETSTGDQRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPPGGAPVLVTCYLTR +SAASAEQRDAAIAQVARAVVA-- +>[subseq from] Beta-lactamase n=2 Tax=Salinisphaera TaxID=180541 RepID=A0A423Q3Q8_9GAMM +--TFRAEIADLEKRHGGRLGLAVLDTAGGQRV-AQRADERFLMCSTFKLPLVGLILSRVD +AGKESLDRHITYDAGDVVTYSPETGQHVGTGMTLGAICRAGLTLSDNTAANLMLRSVGGP +AAVTAFVRALGDTVTRSDRYETALNAYTPGSDRDTTSPSAMGHLMQRLLLDDVLAVPSRE +QLTRWLIANETGDHRLRAGMPGHWRIGDKTGSGGNNTANDIAIVWPQPDAPVIVSAYYAG +SDAGRSQRDRVLADVGRATV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhodoferax saidenbachensis TaxID=1484693 RepID=A0A1P8KAH8_9BURK +-tQITAALQKLEAQAQGRLGVHLLDTASGQEY-GYRSDERFMMLSSFKLLASALVLARAD +RGQESLERRIRYGRQDLVPWSPVTEAHVDGELTLAQLCHATITTSDNTAANLILASYGGP +QALTAFARQLGDTVTRLDRKEPELNV--RKGILDTTSPRAMAKTLQTLLLGNALSSPSRQ +LLQQWMLANTTGGKRLKAGLPEGWGIGDKTGTNKT-SANDIGILLPPQGAPMVVTAYLAD +SAVSSQRREDAIAEVARVVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI0005E4932E +--MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFILAAAVLQRVD +KGELRLMQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP +PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAGRDAALKAVAEAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF3D85C +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIADATKIALN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2A8CIL3_9BACI +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIADATKIALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI00114284D0 +----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +NGFEKSLKQIGDHVTKSNRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID5614 TaxID=2690306 RepID=UPI001371FD55 +------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +EGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Microbispora rosea TaxID=58117 RepID=UPI0009705505 +-----SQFAALERKHGARLGVYVLETGTGASL-AYRADERFAFCSTFKALAAAAVLHQNP +--VSHLGKRVTYTGADVNSISPITKDHIATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP +ARLTAYLRRLGDTVSRMDNYEPELNRDRPRDPRDTTTPRAIAADYQKLVLGEALSAGKRA +LLKDWLVRNTTGAKRVRAGLPKGWTVADKTGTGDYGRANDIAIVWPPHTAPLVMAIMSDR +PGYHTPPKDSLIAEATARIV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. TM32 TaxID=1652669 RepID=A0A4Q1RMR6_9ACTN +---AHAALRRLERAHRARVGAFAHNTRTGATV-AYRADTRVPLCSVFKTLAVGAVLRDLD +HNGETLARRVHYTAADVVPNSPVTSQHTVTGMTIAELCAAALQRSDNTAANLLLRALGGP +TAVTDFARSLGDRTTRLDRWEPELNSAEPGRTTDTTTPAAIARTYARLLLGDALTPSDRG +RLTAWMKANETNTERFRAALPKDWALADKTGTGSYGTGNDVGVAWTPDGTPLVLAVLTGT +AQQADPSDDPLVAGVTRVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI00048D4FE2 +--DLDHEFRQLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYASTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAVAEAAVRYSDNTAGNLLLDHLGGP +ERFEKELKGIGDTVTDAARYETDLNEATPGDPRDTSTARALTEDLREYAVDDALEPGDRD +TLNGWLRGNTTGGELIRAGVPDGWVVGDKSGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T388_9BACT +------AAQQAETELNARVGLVIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLDALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLIAAIYLTQ +SDASMEQRNAAIAAIGTALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora avicenniae TaxID=1198245 RepID=A0A1N6VJX6_9ACTN +--AVDREFRRLETEFDARLGVLAVDTGTGTTV-QHRADERFAYASTFKALAAAMLLDRTS +--ATELDQVVRYSRSDLVAHSPITEQRVATGMRLRDVADAAVRYSDNTAANLMLGHLGGP +DGFERELRRLGDTTTEADRYETALNEGRPGDRRDTTTPRAFATDLRAYAVGDALSQEDRD +VLNGWLRKNTTGDALVRAGVPAGWTVGDKTGGGGYGTRNDIAVLWPPEGAPIVLAVMSSR +DAENAAYDDALIARATRVVV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces asterosporus TaxID=285570 RepID=A0A514JTJ7_9ACTN +-------LAGLEREYGARLGVFAVDTGSGATV-VHRADERFAFCSTFKTLAAAAVLDRGP +--LDRLERRVTYTRADLAAYSPVTERHVDTGMTLRQLCDAAVRYSDNTAANLLLRHLGGP +RALTTHLRGLGDRVSRLDHYEPELNRNPPGDPRDTTSPRALTADYRALVLDDALPAEKRE +LLRDWLVRNKTGGRRIRAGAPRGWTVGDKTGTGDWGRANDVAVLWPDRGEPIVLAVMSER +PDRAAEPSDALVAEATRRT---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 94 TaxID=2035218 RepID=UPI000C1A92F3 +hrDTHAGLRELEARHGARIGAFAYNLRTKATV-RHRAAERFPLCSVFKTLAAAAVLRDLD +RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGSTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PAQDAAPDSPLVAAAASVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=A0A3E1LAW0_XANCA +--MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP +PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPVAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAGRDAALKAVAEAVR--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2A8F241_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKTLREMGDIVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Chromobacterium sp. LK1 TaxID=1628193 RepID=A0A0J6KFW7_9NEIS +---LSRQLAELEHNAGGRIGVAALEVDSGRRV-AYRADERFPMCSTFKLLLVGAVLQLSA +AQPDLLYRHVNYQREQLLRYSPITEQYAEQGMSVKDLCDAAMRFSDNTAANLLLGLLGGP +EAVTRFARALGDGLSRLDRIEPELNSATPGDPRDTTTPAAMVSNLNTLLFSSLLPERQRV +LLRDWLLNSTTGNLRIRAGLPAEWRVGDKTGSGGNGATNDVAVAWRPGKSPLLLAVYYWG +SSALPDERNAVVAAAARVVVAEf +>[subseq from] Beta-lactamase n=1 Tax=Sorangium cellulosum TaxID=56 RepID=A0A2L0EUI2_SORCE +--------------------MAALDTATGARV-GHRAAERFAMCSTFKALLAASLLARVD +QGKLTLDRRVTYRASDLLEHAPVTRAHLAEGLTVEELCAAAVEISDNTAANLLLAQIGGP +AGLTAYIRSLGDQVTRFDRNEPTLNTNVPGDPRDTTSPDAMTDTIRVLLVGDALSEASRA +RLKSWMVRSTTGLARLRAGLPKDWVVGDKTGTGENGAANDVAVAWPPSRAPIVIACFVDA +PSASVDARNAAHAEAARIVAEVf +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID14515 TaxID=2706074 RepID=A0A6B2Z2G5_9ACTN +------DFKELERKFDARLGVYAIDTGTGREV-AHNDRGRFAYNSTFKALQAAVVLRTYS +--VAGLDRRVTYTREDLVANSPVTERHVDTGMTVGELCDASVRYSDNTAANLLFDHVGGP +KGLDSALETIGDRVTRMDREEPDLSRWVPGEKRDTSTPRALAEDLRAFVLGKALEKPERA +QLTTWLRTNTTGAKVIKAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Rubrivivax gelatinosus (strain NBRC 100245 / IL144) TaxID=983917 RepID=I0HQQ0_RUBGI +------AFGAIERSVAGRLGVWAYDLETGRSL-GHRQDERFPMCSSFKWLLAAAVLARVD +RGQERLERRIVFGREALLEYAPATSRRAGGAMTVAELCEAAVTLSDNTAANLLLDTLGGP +AGLTAWVRTLGDRTTRLDRREPDLNEARPGDERDTTTPQAMVLALRQALFGGGLSRRGGD +LLLQWMVASTTGAKRLRAGFPADWRIGDKTGTGAQGTTNDVAVVWAPGRAPLLLAAYLTE +SQAVIEAREAALARVAG------ +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. f150 TaxID=1827699 RepID=UPI000BF1DEEB +------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALPAPERA +QLTTWLRTNTTGDAVIKAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2T0DMP8_9BACI +----RHSFVKLEKEYDAKLGIYALDTDTNQTV-TYRSDERFAYASTHKALAVGTLLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPKRFEPELNEVQPGDTRDTSTAMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGAYGTRNDIAIIWPPNKKPIVLAILSNH +AKEDAKYDDKLIADATKIVLN-- +>[subseq from] class A beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=UPI00114F7D34 +-------LAGLEREYGARLGVFAVDTGSGATV-VHRADERFAFCSTFKTLAAAAVLDRGP +--LDRLERRVTYTRADLAAYSPVTERHVDTGMTLRQLCDAAVRYSDNTAANLLLRHLGGP +RALTTHLRGLGDRVSRLDHYEPELNRNPPGDPRDTTSPRALTADYRALVLDDALPAEKRE +LLRDWLVRNKTGGRRIRAGAPRGWTVGDKTGTGDWGRANDVAVLWPDRGEPIVLAVMSER +PDRAAEPSDALVAEATRRT---- +>[subseq from] class A beta-lactamase n=1 Tax=Verrucosispora sediminis TaxID=547162 RepID=UPI000B852AE2 +-----VDFAPLEREFDARLGVYAIDTGSGSTV-THRADERFAYASTFKALAAGAVLAATS +--TEELDQVVSYSRDDLVTYSPITERHVDTGLSLRAIADAAVRYSDNTAGNLLLKQLGGP +SGFMQALREVGDEVTEPVRWETELNAYVPGERRDTSTPEALATTLRAYAVDDALSPDDRA +LLVDWLKRNTTGDKTIRAGVPEGWAVGDKTGSADHGTRNDIAVIWPPDRAPIVLAVLSDR +AEPDAERDDALLARATELTLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillales TaxID=1385 RepID=UPI00048C4B97 +-------FENLENEYDARLGVYAIDTGSGETI-AYRADERFAYTSTFKALASGAVLMQNS +--VEDIDEMISYSAEDLVTYSPITEKHISTGMTLRDIMDAAIRYSDNTAGNLLLKQLGGP +DGFEAALRQIGDMVIQADRYETELNEAVPGDDRDTSTARALATSLNAFALGDVLPEDKQT +ILTDMLRGNTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDIAIVWPPEGDPIVLAILSSR +DAQDADYDNALIAKAAEAAL--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=T1T7P6_9BACT +-hSVQKQLAQLESSAGGRLGVAAINTANNQRI-EYRSEERFPLCSTSKVMAVAAILHNSS +TDAKLLATNLRYTQQEVAAYAPIAAKHVATGMTVGAMCQATLNYSDNLAMNELLKELGGT +KAVTAYARKIGDNSFRLDRKEPELNSAIPGDLRDTTTPLAMQNSLQTLVLGNSLAPTQRQ +QLQEWLKNNTTGSARISAGVPKNWLVGDKTGTGKYGTSNDVGVIWPTGAQPIVLAIYFTQ +NKPDAKANDQVIADATRIVVAEf +>[subseq from] class A beta-lactamase n=1 Tax=Thermocrispum municipale TaxID=37926 RepID=UPI0004207B46 +-dELASRFRRLENKFAARLGVYAIDTGSGTEV-KYRADERFAYASTFKALAAGAVLARRS +--PADLERKVRFTSDDLVTYSPVTERHVGQGMTVRELIDAAVSYSDNTAGNLLLAELGGP +EGLARALRAIGDRTTHVDRWEPDLNDHTPGDVRDTSTPRALATSLRTYVLGTALPEGRRK +ILVDALIGNTTGDAVIRAGVPHRWTVGDKTGTASHGTRNDIAVLWPPDEAPIVLAVLSDK +RDADADPDDALLAEATKVVL--- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEBF7B1 +--ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS +--IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFEPELNEGTAGYIRDTSTAKAIATNLKAFTVGNALPAHKRN +IFTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEAAEVVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF6F5E7 +----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALLTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF2BCD2 +----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALLTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CdTB01 TaxID=1725411 RepID=A0A0U3P1H6_9ACTN +------PLTELEREHGARLGVFAHHLRTRRTL-AHRADERFPICSVFKTLAAAAVLRDLD +RHGEVLSRRIHYTRDDLVDGAPVTDEHLAHGMTIAELCDAAVRYSDNSAGNFLLRELGGP +TAITRFARSLGDPVTRLDRWEPELNSAEPGRRTDTTSPRAIGRTNARLLLGDALNPSDRA +LLTHWLLNNTTGGTRIRAGVPGTWAVAEKTGSGSYGTTNDVGVAWTADGDPIVLAVLSTK +PDRDAAWDSTLIASAAGVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000762AF3F +---SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB03234 TaxID=1703937 RepID=A0A1Q5LXG3_9ACTN +------RLRALERRHGARLGAVARNTVTGATV-LYRADERFPMCSTFKTLAAAAVLRDLD +RHGEVLAKRIRYTRDDLVENSDTSEEYLATGMTVAELCWAAICHSDNTAANLLLRELGGP +AAVTRFCRSIGDGTTRLDRWEPELNTCEPWRVEDTTTPAAIAGTYERLVLGTALNRPDRE +RLTGWLLANTTSTYRFRAGLPADWRLADKTGGGAYGTNNDVGVAWTPDGTPVVLAVLTTK +PAQDAPADNPLVRDAASVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas oryzae pv. oryzae TaxID=64187 RepID=A0A411XWC9_XANOO +--MLRAQWAEIERGTGGRLGINLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP +AGLTGFLRDIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRK +QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGTDTRNDISILWPPKGAPLLLTTYLNG +AKIDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0002299CCE +----DREFAKLEEKYDAHLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDEVTLPERFEPDLNEVNPGETHDTSTARALATSLQTYVLGQALPEDKRE +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGSGSYATRNDIAILWPPKGDPIVLAILSDR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces acidiscabies TaxID=42234 RepID=A0A0L0JDA4_9ACTN +-aATRDVFAGLEQEYAARLGVFAHDTATGRTL-THRADERFPMCSVFKAPAAAAVLREGV +----DLTRRIHYTQQELTDYAPVTEKHLDTGMTVEELCAAAVSHSDNAAANFLLRELGGP +TAITRFARSLGDPVTRLDRWEPDLNSAEPWRKTDTTTPHAIARTYAKFLLGDVLPPADRT +RLTSWMIANSTNTTRFRAGLPADWILADKTGGGSYGVANDVGVVWPPGRPPLVIAVLTTT +YAAEGPSKNELVARAAELVAA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Prauserella sp. PE36 TaxID=1504709 RepID=A0A365Z7V8_9PSEU +--TAEREFGELEQRFDARLGVYAVDTGTGREI-SHRADARFAYCSTFKALATAALLSERT +--IAELDEVVPYTVDDLVTFSPVTEKHAGAGLPLRELMDAAVRYSDNTAGNLLLRELGGP +KGLQAALREVGDQTTHVDRFEPELNEATPGDIRDTSTPRALATTLRAYALGDTLTADKRA +ILIDMLRRNLTGDELVRAGVPDGWVVGDKTGTGGYGTRNDIAVVWPPDRAPIVIAIMSSR +AEQEAEPDNALLAEATKTVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Sciscionella sp. SE31 TaxID=1445613 RepID=UPI0004DF7C03 +-----DRLRALERAHQAHLGVYARNLRTGATM-THRAGERFGMCSTFKVLAASAVMRDRD +GDGTFLDRIVHYTEADLVENSPITENHVHGGMRIAELCHAAICYSDNTAGNLLLRQIGGP +AGVTRFCRSLGDRVTRLDRWETELNDIAPGDPRDTTTPRAIGENYARLALGTALDPVHRA +RLTGWLIGNTTSAKRFRAGLPDSWLIGDKTGSGAYGSGNDVGIAWTGTGTPLVLAVMTRK +HEPKADYDDELIAEAARICAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ERV7 TaxID=1322334 RepID=A0A197SM95_9ACTN +-----ADFKELERKYGARLGVYAVNTGDGREV-AWRDGERFAYASTFKALAAGAVLRKYS +--LDGMTKLITYSKDDLVANSPVTEKHVDTGMTLGELCDAAVRYSDNTAGNLLFDALGGP +KGLERALRETGDTVTRVERREPDLNQWAPGTVRDTTTPRALAKDLRAFVLGDRLGTAERA +QLTRWLRTNTTGGELIRAGVPKGWTVGDKTGAGGYGIRNDIAVVWPPDAAPIVVAILSNR +GTKEADYDNKLIADAAAVAV--- +>[subseq from] BKC/GPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Shinella zoogloeoides TaxID=352475 RepID=UPI001323ACD4 +---LEKRLADLEARHKGRIGVAIHNLATGVRV-GHRADERFLMCSTFKALLAAHILARVD +RKEEALDRRIVVKKSDLSEWSPVVEKRVGGNISIAELCEAAVTLSDNAAANLLLTASGGP +KALTAFLRGMGDEVTRLDRTEPTLNYETPDDERDTTTPAAMAETLRRLIIGDVLSPRSRA +QLAAWLVMNKTGDTRLRAGLPADWLTGDKTGTNGHGNANDVAIAWSPDRGAVVVTAFCEI +PGISGDERNAVIAEIGRIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus bacterium TaxID=2053512 RepID=A0A3D0E3F1_9BACI +--NIDEKFTQLENEFDARIGVYAIDTGSNQTI-EYRPEERFAFASTYKALAAAILLQQNS +--LEELQEVITYTEDDLVTYSPITEKHVDTGMTLLELSEAAVRFSDNTAGNLLYEALGGP +KGFEQALREIGDNVTKADRFEPDLNNFTPEDTRDTSTPRALATSLQAFAVSDLLTDDKQE +LFTDWLKGNATGDTLIRAGAPEGWEVGDKSGAGGYGTRNDVAIVWPPNREPIVIAILSRH +NTEDAEYDDTLISQAAEIALN-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium jaguaris TaxID=1312183 RepID=A0A387FUF7_9RHIZ +--DAEKQLADLEKKTGGRLGVSVLDTETNISL-GYREGERFALCSTYKALAVGFVLARVD +QGLEKLDRRVTYGNDAVVTYSPATEKHAGTDMTIAELCGAAITLSDNTAGNLLLDSFGGP +SALTAWLRTTGDTETRLDRKEPDVNQAIKGDPRDTTTPDAMLDTIGLLTLGNTLSETSRD +QLSIWLVNNTTGNARLRADLPKEWKVGDKTGTGQNGSYADVAVIWPTDRGPILVTTFVGE +ATAPAKDIEAVFAEVGKIIV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9LAR7_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGEFCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEAFPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERN-------------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI000D07F9CF +----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +NGFEKSLKQIGDHVTKSNRFETELNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNDLIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. W1SF4 TaxID=2305220 RepID=A0A3S8Y2K0_9ACTN +--RVARALAALEREHGARLGVYALETDTGRTV-THRADELFPMCSVFKTLAAAAVLRDLD +HDGSVLARRVHYTQADIDRYSEWTKRHLANGLTIAELCEVSITYSDNTAANLLLRELGGP +DAVTRFARSLGDPVTRLDRWEPELNSAEPDRVTDVTTPRAIARTYARLVLGDALGRADRG +LLTGWLCANTTSGARFREGLPAEWRLGDKTGGGSYGTNNDVGIVWRPHGAPLVLAVLTTK +PAQDAKADDALVSGAARVLAKAf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNH189 TaxID=1136432 RepID=UPI0004670862 +------NLAALEREFGARLGVFAVDTGTGATV-VHRADERFALLSTFKTLAAAAVLERRP +--GARMDERITYGEADLVPYSPVTEKHLATGMTMRQVCDAAVRYSDNTAGNLMLRDLGGP +RALTAYVRGLGDRVTRLDHTEPELNNNPPGDPRDTTTPRVIAADYRALVVGDALPGAGRA +QLTDWLVRNTTGDRRIRAGVPRGWKVGDKTGSGEWGRANDAAVLWPGNGSPLVLSVLTER +PDRDAAAADELVAEATRRVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SPY7_9BACT +-----------------------------TQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLFNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. A202 TaxID=2572899 RepID=A0A542F426_9ACTN +--AAEQEFQRLEKTFQARLGIYAVDTGTGRTV-EHRPDERFAYASTWKALAAAEVLDGTT +--DPELDRVVRYSAQDLVSHAPITEKHVAEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +QGFEKKLRGIGDTVTDPARYETALNEATPGDRRDTSTARALAGDLRAYTVGDALTPADRD +VLLGWLKGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVVAVLSSR +DKLDATPDDALIAQATTVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Synechococcus sp. BO 8801 TaxID=169670 RepID=UPI000B985402 +---AEVALAALEARSGGRLGVFAIDTASGARI-GHRADERFPLCSTFKAILAGAVLHRSQ +RQPGFLEQRIRFGREDLVTHSPIAEQHLEGGLTVAEMAAATVQYSDNTAANQLMARLGGP +AGLTAFARSTGNRTFRLDRWETALNSAIPGDPRDTDTPSGMGTSFQALVLGSALDLPQRR +RLQDWLIGNTTGDRRVRAGVPPGWRVGDKTGTCGYGTANDVAVLWPPERGPIVLAIFHTQ +VDPAAQAQDGVLAAAATIVAEAf +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis potens TaxID=1246458 RepID=UPI00034CFD6E +--AAEKEFKELEKEYDARLGVYAVDTGSEEEI-GYRADERFAFCSTFKALAVGALLDRFP +--DEKLDEVVTYSEEDLVDHSPITEKHVDTGMTLRDISDAAMRYSDNTAANLLFDQFGGP +KGLEAQLGEIGDETTSMDRYETELNSAIPGDERDTSTPRALASDLREYALGDTLKEEERV +FLTDLLKGNTTGDALIRAGVPDDWKVGDRTGGGDYGTRNAIAVLWPSDGDPIVVSILTTR +DDKDAEWQEALVADAAEVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DC5C10E +----DQEFRRLEEQFGARLGIHAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT +--DAQLDRVVRYSTRDLVAHSPITEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +AGFEAKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALEPADRD +VLRAWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DRKDATPDDAVIAQATRVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Actinopolyspora sp. DSM 45956 TaxID=2512148 RepID=A0A4Q8ATH7_9ACTN +-----EDFERLEREFDASLGVYAVDTATGREL-SYRADERFAYASTHKALTAAAVLRRTS +--LEGLDKRITYDRSDLVAYSPVTKKHVDSGMTLRSVLDAAVRYSDNTAANLMFDELGGP +EGLSAVLREIGDATTHVDRIEPELNATEPGDIRDTSTPRALATSLRAFTVGNALPKDERA +VLNRMLRNVTTGDELIRAGAPDGWRVGDKSGAADYGTRNDIAVLWPPERAPIVLAVLSDR +DAADAEYDNALIARAAEVALRSf +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces albus TaxID=1888 RepID=A0A6C1C6V2_9ACTN +--KARRAFVRLERKFDARLGVYALDTGSRRSI-AHRADERFAYCSTCKAFLAGTVLKRNS +--LREMERRVRVRPQDLEGYSPIARKHVGSTMSLRELCDAAVRYSDNAAANLLFRELGGP +KGLQDALRDIGDRVTRADRYEVELSEGTPGDSRDTSTPRALATDLRAFVLGDVLPGRKRE +VLTDWLKRNTTGDKLIRAGAPRGWEVGDKTGNGGYGTRNDIAVLWPPKGDPITLAIMSRR +DTRDAEHDDALIAEAAEVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. WAC 01424 TaxID=2203200 RepID=A0A429A9T9_9ACTN +----RARLAALERRHGARLGVYALATGTGATL-AHRADERFAFCSTFKALAAAAVLHRNP +--LSHLDDRVTFTRADVDSISPITQHHVATGMTVRELCEAAIRYSDGTAGNLLMRDAGGP +ARLTAFLRGLGDRVSRIDHYEPELNRMGPKNPRDTTTPRAIAADYRALVLGDVLDPAKRA +LLEGWLVRTTTGTARIRAGLPKGWKPAHKTGTGDHGRANDIAVVWPPGVPPLVVAVMSDR +PGYGTPPREALIAEATRVIVA-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. CPCC 101271 TaxID=2656746 RepID=UPI001291A2AF +-----PDFAALEAASGGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKFVLCAAVLRQVD +AGRLDLDKRVPMRAEDLIDHAPVTRRHIGKDLTVRDLCRATMITSDNPAANLLLGVVGGP +PAVTRFLREHGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRFLLGQVLAPASRQ +QLADWLIDNETGDERLRAGLGSTWRVGDKTGSNGKDTTNDIAMLWPMGGAPWVLTSYLQG +ATVDDAGRNDVLRQVAV------ +>[subseq from] Beta-lactamase n=1 Tax=Bacillus lentus TaxID=1467 RepID=A0A2X4VYF0_BACLE +--NTDKKFAQLENDFDARLGVYAMDTGSNQTI-EYRPEERFAFTSTYKALAAAIVLKQNT +--MEELKEVIPYTEDDLVSYSPVTDKHVGTGMTLRDIGEAAVRYSDNTAGNLLFKELGGP +KAFEQALRQIGDDITQADRYEPELNAFTPGDPRDTSTPKALATSLEAFVVGDILSDDKRE +LFTDWLRGNATGDTLIRAGSPENWEVGDKSGAGSYGTRNDIAVVFPENREPIVIAIMSRH +DTENAEYDDALIAKVSEVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TRM44457 TaxID=2508722 RepID=UPI0010099BB8 +---ARRRLRALEREHGARLGAYAYDTGSGRLV-TYRADERFPMCSLFKALNAAAVLRDLD +RDGSFLARRVFYTEQYVKRWSPVTKAHVADGMTIAELCEYSITESDNTAANLLLRELGGP +AAVTRFARSIGDGVTRLDRWEPELNTAEPWRETDTTTPRAIARSYGRLLLGGALAPGDRH +LLTGWMLANRTSGNRFRKGLPADWVLADKTGGGEYGSNNDAGVAWPPGRPPVVLAVMTTK +PEQD-AADDALVAGAAAVLAE-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011A45AAE +-qATHKEFSQLEKKFDARLGVYAIDTGTIQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDLLNEVITYTKEDLVDYSPVTEKYVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSK +DEKEAIYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Paramesorhizobium deserti TaxID=1494590 RepID=A0A135HNP7_9RHIZ +--KLENELAKLEDRHGGRIGVAILNLATGDKI-GHRADERFLLCSTFKALTAGYILARVD +RGEEELDRRIVHAKKDLVTWSPITEKHVGGAMSVAELCLATVTLSDNTAANLLLNSFGGP +AGLTAFLRSIGDETTRLDRFETELNHEKPGDLRDTTTPAAMLETLRKLLFGDVLSRSSRA +QLAAWMVMNKTGDEKLRAGFPADWMIGDKTGGNGYGNSNDVAVAWSPDRGAVIVSAYCEI +PSVSEKERAAILAEIGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus lentus TaxID=1467 RepID=UPI000DBE18FE +--NTDKKFAQLENDFDARLGVYAMDTGSNQTI-EYRPEERFAFTSTYKALAAAIVLKQNT +--MEELKEVIPYTEDDLVSYSPVTDKHVGTGMTLRDIGEAAVRYSDNTAGNLLFKELGGP +KAFEQALRQIGDDITQADRYEPELNAFTPGDPRDTSTPKALATSLEAFVVGDILSDDKRE +LFTDWLRGNATGDTLIRAGSPENWEVGDKSGAGSYGTRNDIAVVFPENREPIVIAIMSRH +DTENAEYDDALIAKVSEVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas vasicola TaxID=56459 RepID=UPI000531F6D0 +---LRAQWAEIERGTGGRLGISLLDSATGWHL-GQRQDERFPMCSTFKFVLAAAVLQRVD +QGKLMLAQRVKIRASDMLEHAPVTERHIGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRSIGDAQTCSDRHEPDMNRFAAGDPRDTTTPAAMANTLRTLLLGDALRPASRK +QLTDWMINNRTGDDCLRAGLTRDWKIGDKTGSNGIDTRNDIAILWPPKGAPLLLTAYLNG +AKVEDAARDAALKAVAVAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella cf. planticola B43 TaxID=95610 RepID=UPI0005B261FE +--ILQKKIEMLENKSGGKLGLTVVDTSDGTTY-SWRGDEKFPLCSTSKVMVVAAILKESE +SNTNLLAKKITINKSDMVNYNPITSKYIDSSMTITELSKAALQYSDNAAMNKLLSYLGGP +RHATQFARTIGDKAYRLDRNEPGLNTAIPGDSRDTTTPSAMADTLNKLILGTALKKEQKA +KLTEWMKGNTTGLNSIKAGLPAEWKVADKTGSGDYGTTNDIAVIWPKNHAPVILTTYFTQ +PEKDASARKDVLASAAKLIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Sediminibacillus albus TaxID=407036 RepID=A0A1G9A128_9BACI +--DLDEEFSQIEEAFDARLGVYAIDTGTNQSV-KYNPDERFAYSSTFKLLASAFLLKQND +--LKDLEKVVTFVKDDLVTYSPVTEKHVDTGMTLLEISEAAIRKSDNTAGNLLLNALGGP +ENYKQALREIGDDVTQPERYETELNEFSPGNKRDTSTPRALANNLRKVVLGDFLPREKQE +LLIDWMKGNATGDALIRAGKPEGWTVGDKSGAGSYGTRNDIAIVWPPGREPIVIAVMSRH +KTKDAKYDDELVARAAEVTLNAf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A7XH39_9BACI +----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILTIEKRN +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIADATKIALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI000997DDA3 +-----AELAELERRHGARLGVYARNVRTGRTV-VHRAEERFAMCSTFKAFAAAAVLRDHG +-DRAPLDRVVHYPPRDILPNSPRTEENLATGMTVAGLCAAAIQYSDNAAGNLLLRELGGP +AGLTRFLRSLGDTVSRLDRWEPELNTAIPGDVRDTTTPEAIAGSLERLTLGRALRRADRE +RFTGWLKGNTTSAERFRKGLPSAWVVADKTGTGDYATANDIGVAWTTRGTPVVLAVLSDK +SAPDAPVDQALIAEAAAIVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS043905 TaxID=2033504 RepID=A0A2C4R755_9BACI +--ATIKKFEQLEKEYDAKLGVYAIDTGTKKTV-EFHENERFAFTSTHKALAVGALLHQKS +--IEDLNQRITYTNEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP +AGFKKALEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWAVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DEKEADYNDELIAEATEEVIK-- +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Tokpelaia hoelldoblerii TaxID=1902579 RepID=A0A1U9JTU4_9RHIZ +--------KELERQSGGRLGVYVLDSRSKQEF-SYRGDERFAMCSVFKWLLAAAVLARVD +AGQEKLDRIIRFKKADLMEYSPGTKQFVDGPMSIAQLCKTAITISDNTATNLLLDKLQGL +AALNAFLHSKGDNTTRLDRLEPDLNEARPGDERDTTTPEAMGGNLQRFLTGGSLSTSSRK +QLTEWMLATRTSGERLRSGLPSGWRLADKTGTGSNGTANDVGVYWTPTGEPVFVCVFLTE +TSIDRAEQSKVIADIGKKI---- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacteria TaxID=2 RepID=A0A097SRP9_9ACTN +--ETLVKVKDAEGQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQAT------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. EN16 TaxID=212773 RepID=UPI0008515809 +----GRAFAALEKEYAARLGVYAVDTGTGRAV-AHRDGERFAYASTFKALAAGAVLRRYG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAKPERA +RLAQWLTANTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +TDADADYDNTLIAKATSAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEFAE1F +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDIVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000346D1E1 +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPEDKRA +LLTDLMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8N388_9BACI +-----HSFVKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIADATKIALN-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia nova TaxID=37330 RepID=A0A2S6AWN5_9NOCA +-----AEFHDLEARLRGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP +--PAELDRRITYTRADLVPNSPVTEQHVDQGLTLREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHFVLDPSVAADDRD +VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGDYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDAEYDNAAIARAATIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS026049 TaxID=2033493 RepID=A0A2A8FJ69_9BACI +--ATIKKFEQLEKEYDAKLGVYAIDTGTKKTV-EFHENERFAFTSTHKALAVGALLHQKS +--IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP +AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWAVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DEKEADYNDELIAEATEEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF7E141 +----HNSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEGAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Reyranella sp. CPCC 100927 TaxID=2599616 RepID=A0A5C5TEK2_9PROT +---LAGDLAKLEAESGGRLGVAVIDTASGIQV-GHRIDERFLMCSTFKLLAAAAVLARVD +AGKEKLDRRIRFESGDILPYSPATKDRVGGMMSLAELCEAAMVLSDNTAVNLMIATFGGP +PGLTAYVRSLGDTVTRHDRSEPGLNDA--DGVLDTTTPAAMAANIRTLVLGTALSEASRQ +QLTAWMIGNKTGDTRLRAGLPRDWRIGEKTGSGK-GTSNDIGLGWPPGRAPVIMAVYLTG +TSASAERQHATIAGVGRAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. SHU 199 TaxID=1591174 RepID=UPI0003A484A9 +--TLPQRLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD +RGELALERRVPVRKADLLANAPVSERHVGGTLSVVELCRAAMIYSDNTAANLLLPLVGDP +PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPRDTTTPAAMAATMRALLLGEVLQPVSRQ +RLIAWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG +ATVDSAARDATLKAVAQAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SN1 TaxID=2055158 RepID=A0A2M8T636_9BACI +----IKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKANRFETDLNSAVPGDIRDTSTAKVLATDLNAFTVDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIILAILSNR +FTKDAHYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD184 TaxID=1053242 RepID=R8U3R6_BACCE +-qETYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVEKRK +ILTERMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK +DEKEATYDNQLIAEATKVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X8W4_9BACT +--TLQQKLASFEKMSGTKIGAAAINTADNTYL-QYRATQRFPLCSTFKVMVTAAILQKSM +AESDLLQQKIYYKKQDFVYYSPVTEKHLADGMTVAELSAAAMMMSDNTATNLLLKKLGGP +QAVTAFARSIGDQIFRNDRFEPDMSSSIPGDIRDTSTPLAMASSLRRLVLGDNLGLVQRQ +QLQTWLIGNTTGDKLIRASVPQGWTVGDKSGKGDYGTRNDIAIIWPLHGAPIVMAIYTTQ +SIKDAESRDAVVAGVARILLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI00056497A9 +--QFHDRLLELEKKFDARLGVYALDTEGGATV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVTYARGDLMKHAPVTGQHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +GELTAFARSIGDTVTRMDRIEPAITEATPGDPRDTTTPRAFGTDYQKIVLGDTLTADKRE +FLSDLLRRNVTGAGRIRAGLPGGWTVADKTGTGEYGTMNDFAIVWPPGKAPIVVAIMSSK +AAKDAPYDEALLAEAAKYVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. DUT11 TaxID=1914992 RepID=UPI0010083CD9 +---TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS +--LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATVRYSDNAAANLLFRELGGP +RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR +DVKDAESDDALIAGAAKVALEAf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF8AEA9 +---SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. LMG 8992 TaxID=1591157 RepID=UPI0013717CF9 +--TLQQRLADIERRSGGRLGVSLLD-GSGARLgGQHQDERFPLCSTFKFLLAGAVLQRVD +RGELSLERRVPVRKADLLGNAPVSERHVGGTLSVAELCRAAMIYSDNTAANLLLPLVGDP +PGVTRFLRALGDTQTQLDRNEPGMNDFVAGNPRDTTTPAAMAATMRTLLLGEALQPVSRQ +RLIGWMRDNRTGKDCLRAGLPAGWQIGDKTGSNGTDTRNDIAIIWAPGRTPLLLTAYLNG +ASVDSAARDATLKAVAQAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. AR2-1 TaxID=2217816 RepID=UPI0011EE4637 +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIADATKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Hydrogenophaga palleronii TaxID=65655 RepID=UPI000AAE1403 +--TLQAGLREIEARARGRLGVHIIDTATGREQ-GWRADERFLMLSSFKLLASALVLHRAD +RGEESLERRIRYRAQDLVPWSPVTERHVGGELSLAQLCEATITTSDNTAANLILASYGGP +AALTAYARQLGDTVTRLDRNEPGLNRRADGAPLDTTTPRAMAHTLRTLLLGEALRPASRE +RLGQWLLANTTGGKRLRAGVPADWRVGEKTGTAGD-AANDIGIAWPPQRAPLIVTAYLDD +SATDAATRDAALASVGRLL---- +>[subseq from] Beta-lactamase n=1 Tax=Actinopolyspora mzabensis TaxID=995066 RepID=A0A1G8Y8W1_9ACTN +----HEDFERLEREFDARLGVYAVDTATGREL-SYRGDERFAYASTHKALTAGAVLRQTS +--LEGLDKRITYDRADLVAYSPITKKHVDSGMTLRAVLDAAVRHSDNTAANLMFDELGGP +EGLSAVLREIGDTTTHVDRIEPELNETEPGDIRDTSTPRALATSLRAFTVGNALPKDERA +VLNRMLRNVTTSDELIRAGAPDGWRVGDKSGAADYGTRNDIAVLWPPERAPIVLAVLSDR +DTADAEYDSALIARAAEVAVRSf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BAG6O-2 TaxID=1053193 RepID=J8ZX71_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDFSNYNPITEKHVDTGMTLKELADASVRYSDSTSHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. BK333 TaxID=2512158 RepID=A0A4R6NVQ9_9RHIZ +--DADKQLADLEKKTGGRLGVSVLDTETNISL-GYREAERFALCSTYKALAVGFVLARVD +QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAQLCGAAITLSDNTAGNLLLDSFGGP +SALTAWLRTTGDTETRLDRKEPDVNQAIKDDPRDTTTPDSMLDTIGLLTLGNTLSETSRD +QLSNWLVNNTTGNARLRAGLPKEWKVGDKTGTGQNGSYADVAVIWPTDRGPILVTTYVGE +ATAPAKDIEAVFAEVAKIIA--- +>[subseq from] Beta-lactamase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q5PRG7_9BURK +--RLEAGIRAVEKRSGGRLGVALLDTGSGALH-GWRLDERFPMCSTFKMAAAALVLKRAE +TGEENLDRIVRFGPADQVAYGPVTEPLLPDGLTVGELAGAIVTFSDNTAANLLLRSFGGP +SALTAWLRTLGDDRTRLDRTEPALNTAIPGDLRDTTTPRAMAMTLQRIALGDALKAPSRA +QLIGWMQASRTGDRKFKAGVPAGWRVAGKTGAGANGTSNEIAVLWPPAGAPLVVCAYLTG +AKVESAARDQVIADVGALAA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. LL01 TaxID=1665556 RepID=A0A0J5JNP0_9BACI +-----AEFKDLEKEYDARIGVYALDTGSNKSV-SYRADERFIYASTHKALAVGALLHKKS +--IEDLEELITYTEGDLVNYNPITEKHLGKGMTLKELSDASIRYSDNTAGNLIFNAIGGP +EGFKEVLREIGDNTTEPERIEPDLNNVKPGETRDTSTPKALAESLQAFTLGDALPPEKQN +LLIDWLKNNTTGDALIRAGVPEGWIVGDKTGAGSYGTRNDIAVIWPPKGAPIILAVLSSR +DEADAEYDDALIAKATDEALK-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas cannabis pv. cannabis TaxID=1885894 RepID=A0A0B2CUV9_9XANT +--MLRAQWADIERGTGGRLGISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLRRVD +QGKLTLTQPVKIRAADMLEHAPVTKRHVGGTLSVGELCRATMIHSDNPAANLLFPLVGDP +AGLTAFLRSIGDTKTRSDRYEPEMNGFAPGELRDTTTPAAMASTLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLATYLNG +AKVDAAARDAALKAVAVAVREW- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis potens TaxID=1246458 RepID=UPI00034CAE07 +---VEQAFAELEEEHDARLGVYAVDTGSEEEI-AYQADERFAYCSTFKAMAVGALLREHP +--EEKLDEVVAYSEEDVIGYSPITEKHVDTGMTLRDIGDAAMRYSDNTAGNLLFEQFGGP +KGLQAELREIGDETTSMDRYETELSEAVPGDERDTSTPRALAANLREYALGDSLTDGEQD +YYTDLLERNLTGDALIRAGVPDGWKVGDKTGSGGYGTRNDIAVVHPPDGDPIVIAIMTSR +DEKDAERREALVADAAEVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Weissella cibaria TaxID=137591 RepID=UPI00143F29F4 +----------------------------GKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFWHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia sienata TaxID=248552 RepID=UPI0012ECE9D0 +--ATTQQFTDLEAAHGARLGVFALDTADGRSV-AYRDGERFPMASTFKGLACGALLHEHP +LSSGFFDRVIRYPRTDLVDYSPVTEQHVDTGMTVAALCEAAITVSDNTAGNQILKLLGGP +AGFTAFLRTLGDDTSRLDRWETELNTAIPGDERDTTTAAALAADYRALVVGDSLVEPERA +QLAAWLVASATGGDRIRAGLPTGWKVGNKTGSPAYGSALDVAIAWPPGRAPLVIAVLTTK +SEQNAEPDNALVASAARAAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia higoensis TaxID=228599 RepID=UPI0002F08C98 +------SFAELEANTVARLGVFAVDTGTGRTV-AYREHERFPMASTFKGLACGALLREHP +LSTGYFEQVIHYPATELVEYSPVTEQHVESGMTVAQLCEAAITLSDNTAGNQLLKLLDGP +AGFTAFLRSLGDETSRLDRWETELNSAIPGDERDTTSPAALAADYRALVVGDVLAEPERE +QLSSWLVANTTGDTRIRAGLPDDWTVGDKTGSPAYGSALDVAVAWPPGRAPIVIAVLSAT +TDPGAEADNALIADAARAAVA-- +>[subseq from] Beta-lactamase n=1 Tax=[Brevibacterium] frigoritolerans TaxID=450367 RepID=A0A3Q9SIQ1_9BACI +--ATIKKFEQLEKEYDARLGVYAIDTGTKETV-EFHENERFAFTSTHKALAVGALLQQKS +--IEELNQRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP +AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGNPIVLAVLSSR +DEKEADYNDELIAEATEEVIK-- +>[subseq from] Beta-lactamase n=1 Tax=Verrucosispora sp. CNZ293 TaxID=2035249 RepID=A0A2G7D3P8_9ACTN +------DFAPLEREFDARLGVYAIDTGTGRSV-AHRADERFAYASTFKALAAGAVLAATS +--DEELDRVVSYSHDDLVTYSPITERHVDTGLSLRAIADAAVRYSDNTAGNLLLKQLGGP +SGFKQVLREVGDEVTEPARWETELNAYVPGESRDTSSPQALATTLRAYAVDDALSPADRA +VLVDWLKRNTTGDATIRAGVPDGWAVGDKTGSADHGTRNDIAVVWPPDRAPIVLAVLSDR +VEPDAERDDALLARAAEITID-- +>[subseq from] Beta-lactamase (Fragment) n=64 Tax=Bacteria TaxID=2 RepID=A0A0C5B5N5_ECOLX +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDK----------------- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E32B45A +---LRARWAEIQRGTGGRLGISLLNSVTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP +PGLTRFMRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +AAVDAAARDVALKAVAEAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0010BD8DAD +----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIADATKIALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea TaxID=53335 RepID=UPI00142DE7E3 +-qSLNNQFEKLERQSGGRLGLAVIDTSDSAQY-SWRGNERFPLCSTSKVMAVAAILKKSE +NADTLLNKKIHISQHDMVNYNPVTMKHIGSAMTLAELSAAALQYSDNAAMNKLLAYLGGP +QHATQFARTLGDTTFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNKLVLGSALKDDQKA +TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPIVLTTYFTQ +HDKSAAARKDVLASAARVIAD-- +>[subseq from] Class A beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A657UYB1_9BACI +----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIADATKIALN-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=A0A561PDI3_XANCT +-qSLAQRLAEIERRTAGRLGVTLLD-GAGTVLgGQRQDERFPMCSTFKFVLAAAVLQRVD +RGELSLEQRVDIRAADMLAHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGDP +PGLTRFLRGLGDAQTRSDRHEPEMNQFAAGDPRDTTTPAAMAATLRALLLGDVLRPASRQ +RLTEWMIDNRTGDDCLRAGLPRGWKIGDKTGSNGTDTRNDIAIVWPPGGTPLLLTAYLNG +ARVDSAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. IBTA2 TaxID=2283625 RepID=UPI0013F46EA8 +---TDRAFAELERKFDARLGVYVVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS +--LPQMERLVRYGQEEIISHSPITEKHVDTGMTLRELCDATIRYSDNAAANILFRELGGP +RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAVVWPPGAAPIAIAVLSRR +DVKDAEPDDALIAGAAEVALEAf +>[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. Ad5 TaxID=989436 RepID=UPI0007AE44C9 +-----DTVSQLETEVGGRIGVVLRHTGSDWAV-EHRADERFPMASTFKALLCGAVLSRVD +RGEESLGDLVTYKATELVSYSPITENHVASGMSVGQLCEATVTMSDNSAANLLLKRVDGP +EGLTRFLRGLGDRVTRLDRNEPAMNEARHGDPRDTTSPSAVLKTLDRLLFEDVLLPSSRA +QLQQWMVDDKVADELIRKHLPKGWRIADKSGGGQNGSRGIISVIWPDAGAPYLASVYMMG +SDASFRQRNAVIAEIGKAMIE-- +>[subseq from] Beta-lactamase n=2 Tax=Pseudovibrio TaxID=258255 RepID=A0A165NXD9_9RHOB +-----DTVSQLETEVGGRIGVVLRHTGSDWAV-EHRADERFPMASTFKALLCGAVLSRVD +RGEESLGDLVTYKATELVSYSPVTENHVASGMSVGQLCEATVTMSDNSAANLLLKRVDGP +EGLTRFLRGLGDRVTRLDRNEPAMNEARHGDPRDTTSPSAVLKTLDRLLFEDVLLPSSRA +QLQQWMVDDKVADELIRKHLPKGWRIADKSGGGQNGSRGIISVIWPDAGAPYLASVYMMG +SDASFRQRNAVIAEIGKAMIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF529FF +---SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGNPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 5112.2 TaxID=1938848 RepID=A0A2N3XMC7_9ACTN +---VEAELRDLEQRYDARLGVYARNVRTGRTL-SHRAGERFAMCSTFKAFAAAAVLRDRG +-DRAPLDRVIHYPPHDILPNSPLTQENLATGMTVGDLCAAAIRYSDNAAGNLLLREIGGP +AGLTRFLRSLGDDVSRLDRWEPELNTAIPGDLRDTTTPRAIGGSLARLGLGRALGDADRE +RFVGWLKGNTTSTGRFRRGLPDGWVLADKTGTGSYATANDIGVAWTTRRTPVVLAVLSTR +STEDATVDEALVAEAARVIAR-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q6ZY58_KLEPN +-----EQIKISEGQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTTFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD +TAATMAERNQQIA---------- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas albilineans TaxID=29447 RepID=UPI0005F32494 +--ALQQRLAEIERRSGGRLGVCLLDSGTGQRI-GRREQERFPLCSTFKFVLVAAVLQRVD +RGEIGLDQRVRVRAADVVSYAPVTKPHVGGTLSVDALCRAAMIFSDGGAANLLLRLVGDP +PGLTRFLRAHGDTQTRSDRNEPSMNAFALDDPRDTTTPAAMASTMRTLLLGDVLEPASRQ +RLIDWMIDNRTGDDCLRAGLPAGWRIGDKTGNNGTDSRNDIAIVWPPGRAPLLLTAYLNM +ATVDSDARDAALKAVAQAVVAWw +>[subseq from] Beta-lactamase n=1 Tax=Nocardia sp. MDA0666 TaxID=2135448 RepID=A0A2T2YSK1_9NOCA +-----AEFRDLEARLHGRLGVYALDTGTGRAV-EYRPDERFPYCSTFKALAAGALLSTLP +--PAELDRRVTYTRADLVPNSPVTEQHVDQGMTVREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRAVGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPSVAADDRD +VLTGLLRANTTGAALIRAGVPAGWQVGDKTGGGDYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDAEYDNAAIARAATIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. 1011MAR3C25 TaxID=1675788 RepID=A0A418T7T0_9RHOB +---TLAAVRQAEATLDARAGYASLDLASGRIQ-GYRIDERFPMLSTFKVLVCAAVLARVD +AGEDRLDRHVGYQASQLVEYSPVTEKHVGAGMTLDALCEAAITMSDNTAGNLLLAAVDGP +QGLTDFLRAIGDDTSRLDRWETELNSADPGDPRDTTTPGAMAETLNRLLFGEALSPESRQ +QLLTWMENDRVADALIRAALPQGWYIADKSGAGARGARGIVAALGPDGQPGRIVVVYMTE +TEATLDERNEQIARIGAAIVSDw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI000BEFC2C1 +---SDREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP +EGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR +TEKDAEYHDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. DvalAA-19 TaxID=1839761 RepID=A0A1C4KVH2_9ACTN +---TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS +--LPQMERLVRYGQEEIISHSPITEKHVDTGMTLRELCDATIRYSDNAAANILFRELGGP +RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR +DVKDAEPDDALIAGAAEVALEAf +>[subseq from] class A beta-lactamase n=1 Tax=Fictibacillus phosphorivorans TaxID=1221500 RepID=UPI0011A4DCDD +------VFSKLEEKYDAKLGIYALDTGTNQTV-NYQSDERFAYTSTHKALAVGALLQQIS +--IEDLNQTITYTRDDLVTYSPITEKHVDTGMTLSEIADASLRYSDNTAGNLILKQLGGP +VGFKESLEEIGDYVTTPERYEPDLNEVNPGEIHDTSTPRALATSLQAFTLGEILPIEKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWTPKRDPIVLAVLSSR +DQKDADYNDKLIAEATKQVIK-- +>[subseq from] Beta-lactamase SME-4 n=2 Tax=Serratia marcescens TaxID=615 RepID=Q54488_SERMA +--AAAKQIKKLEEDFDGRIGVFAIDTGSGNTF-GYRSDERFPLCSSFKGFLAAAVLERVQ +QKKLDINQKVKYESRDLEYHSPITTKYKGSGMTLGDMASAALQYSDNGATNIIMERLGGP +EGMTKFMRSIGDNEFRLDRWELELNTAIPGDKRDTSTPKAVANSLNKLALGNVLNAKVKA +IYQNWLKGNTTGDARIRASVPADWVVGDKTGSCGYGTANDYAVIWPKNRAPLIVSIYTTR +KSKDDKHSDKTIAEASRIAIQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ADI92-24 TaxID=1522756 RepID=UPI000F556DC6 +--RTEQAFRTLERKFDARLGVYALDTGSGRTV-THRPDERFAYASTCKALLAGAVLDKNS +--LRQMDRLVRYGRDDLVSASPITEQHVATGLTLRELCDAAIRYSDNAAANLLFHELGSP +RALQDALRALGDNVTRCDRYETALSAATPGDLRDTSTPRALATDLRAYVLGTTLPADKRA +VLTDWLRRNTTGDNTIRAGAPDTWQVGDKTGTGGYGTRNDIAIVWPPGAGPIALAVLSRR +DTKDAERDDALIARAAKVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. Root708 TaxID=1736592 RepID=A0A0Q8MMD2_9RHIZ +-dEIDRRIAALEKQIGGGIGVSVIDTQTNISF-GYRETESFPLCSTFKVLAAGFVLSRVE +KGEENLERRIIYDTDKLVTYSPETGKHVGGDMSVGDLCQAAITLSDNTAANLLLESFGGP +KELTNWLRTFGDASTRLDRWETDLNEAKKDDPRDTTTPDAMLDTLGNLTLGSVLSEPSQN +TLVEWMVANTTGGARLRSGLPDDWKIGDKTGTGNNGCAADIAIAWPPGHGPLLMTVYVKQ +ASVPVADINPVFAEVGRIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus picturae TaxID=171693 RepID=UPI000E68C72A +--KLDEQFAALEDDFDAQLGVYALDTGSNQTI-AYRAEERYAFSSTYKALAAALLLEQNE +--MEELNEVITYTEDDLVPYSPVTEKHVDSGMTLLEIGEAAVRTSDNTAGNLLFDALGGP +AKFEEALREIGDDVTQSDRYETELNEFNPEDTRDTSTPKALATNLKKFAVGDLLTDEKRE +LFTDWLQGNATGDTLIRAGAPEGWVVGDKSGAGTYGTRNDIAVVWPPDREPIVMAIMSRH +DTEDADYDDALISEAAEVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SWG2_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPVAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPSQAPLIAAIYLTQ +SDASMEQRNAAIAAIGAALAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Roseovarius sp. MCTG156(2b) TaxID=1354722 RepID=UPI00068F5F69 +--ALQQTVQDVEARLGGRIGYAMTDLNSGQDW-GYKADDRFPMSSTFKALLCGVILARVD +AGEESLDRRIAFTADDLVTYSPVTETHVDTGMTVGELCRAAITISDNTAGNLLLATVGGP +RGFTASLRDIGDATTRLDRWETALNESTPGDMQDTTTPRAALATLHALLFGDTLKTASRQ +QLVDWMIADAVADDLLRASLPDGWVIGDKSGAGGHGSRSIIAVIWPSPDHPVLAAIYMTG +NDADMALRNAAIAEIGA------ +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. HB202 TaxID=767398 RepID=A0A370RN66_9ACTN +------DFKKLERKFDARLGVYAIDTGTGREV-AHNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIKAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKEAEPDDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albovinaceus TaxID=66867 RepID=UPI000A3C764D +------DFKKLERKFDARLGVYAIDTGTGREV-AHNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIKAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKEAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. es.049 TaxID=1761788 RepID=A0A2N0GD88_9GAMM +---ITAELERIEQTLDARIGFAAHNLATSQRW-EVNADERFAMSSTFKTLACGTLLDQAD +KGQLALETEVSFAESDLVTYSPVTEEYAGHQMTLLKLCDATMTTSDNTAANLVLQALGGP +EAVTAFARHMGDPITRLDRFETELNEATPGDERDTTTPNAMLATLEKLVLGDVLSDESRQ +QLEEWMKGNAVADGLFRAAIPSDWVIADRTGAGGYGSRSITAIIWPPEQAPTLVVFYITE +TEASFEERNAAIAALGEVI---- +>[subseq from] Beta-lactamase n=1 Tax=Frankia sp. QA3 TaxID=710111 RepID=I9A1A9_9ACTN +--QVRQRLVELERGYPGRIGLAAFAPRTGARV-DYRATERFALASTFKVLTAAAVLRRAR +QEPGLLDRLIRWEAGDVVENSPVTGQHTATGLTVAQLCEAALTHSDNTAGNLLLRQLGGP +AAITAFARALGDPATRLDRWEPELNTNIPGDPRDTTTPAAMASTLRALTFGPALAGQDRD +QLVAWLVANTTGGACIRAGLPAGWRVGDKSGAGVRGMINDVAVAWPPGAGPVVIAIYTTR +TDDHAEGDNRIVADVARLVA--- +>[subseq from] Beta-lactamase n=2 Tax=Acidovorax sp. 93 TaxID=2135632 RepID=A0A495FCX2_9BURK +--EWNETLANIERTAQGRLGVAMLDTGSGLQL-GWRQDERFAMASTFKAVLAGWMLALVD +QGKERLDARVHYAAGDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDSVTRLDRTEPTLNEAKVGDPRDTTTPQAMLQTLQKLVLGDVLTPPSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVLWPPGGAPVLVTCYLTR +STAKPEQRDAAIAQVARAVAT-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces atratus TaxID=1893 RepID=UPI00055C730B +------HFAALERKHGARLGVYALATGTGATV-AYRADERFAFCSTFKTLAAAAVLHRNP +--LSRLDERVTFTKAEVNSISPITKDHIATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP +AQLTAYLRGLGDTISRMDHYEPDLNRDRPQDPRDTTTPRAIAADYHKLVLGDALAADRRA +LLTDWLERNITGAKRIRAGLPKGWMVADKTGTGDYGRANDIAIVWPPHTAPLVMAVMSDR +SGYNASPRDSLIAETATQIV--- +>[subseq from] class A beta-lactamase n=1 Tax=bacterium SGD-2 TaxID=2713607 RepID=UPI0013ED1896 +------AARQAEKQLDARVGVAIYDTGSGASW-QYRANERFPMTSTFKVLACGALLARAD +NGLEDLNRSVQIRPTDFVAYSPVTEGWSDQQVPLYKLCEATLLTSDNTAANKVLEALGGP +HEVTAFLRSIGDEVTRLDRWETQLNEATPGDARDTTTPAAIATSLRKLVLGDVLSLSAKT +TLTQWLVDNKVGGPLLRAGIPADWQIADRTGAGGHGSRGIVAVVWPPDHAPMTIAVYITQ +TRAAMEQRNEAIASIGSALAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces viridosporus T7A TaxID=665577 RepID=A0A5J6FUG9_STRVD +------SLADLERAYGARIGVYAVATDTGATV-VHRADERFAFCSTFKSLAAAAVLHRNP +--LSRLDERVTYGRADLAAHSPVTERHVATGMTVRQLCDAAVRYSDNTAANLLLRDLGGP +RGLTTYLRGLGDRVSRLDHYEPELNRNPPGDPRDTTTPRAIAVDHRALVLGDALPAARRA +LLKDWLVRNTTGDRRIRAGVPRGWTVGDKTGTADWGRAHDVAVLWPPRAAPLVLAVLTEH +PDRGAAPSDPLIAEATRRT---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A270ACS9_9BACI +---TIKKFEQLEKEYDARLGVYAIDTGTKKTV-EFNENERFAFTSTHKALAVGALLQQKS +--IEDLNKRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP +AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDILPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DEKEADYNDELIADATEEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ms184 TaxID=1827974 RepID=UPI000BEFE113 +------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +NGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Myxococcales bacterium TaxID=2026763 RepID=A0A4Q5XFT2_9DELT +--DVHSRFAALEERSAGRLGVAAVDAGTGWRI-GRREGERFPLCSTFKLPLVAAVLRRVD +AGQESLSRVIPYDAGALLEYAPVTREHVAQGLSVEQLCEASVSLSDNTAANLLLETLGGP +AGLTAFFRSLGDETSRLDRNEPTLNTALPADERDTTTPAAMVALLSRILVSSTLSDASRA +RLVDWLVRSPTGRTRLRAGLPRGWRAGDKTGTGENGATNDVAIAWPPGRAPLLICAYSIG +SLQSGDQRAETLAEVARIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Ramlibacter sp. WS9 TaxID=1882741 RepID=A0A4Y7B0Z6_9BURK +-----DAWRPLEALSGGRMGVAVLQ-ADGSLQ-GHRLDERFPMCSTFKWLAAAHVLQRVD +RGLDRLDRRIPYGRDALVPHSPVTQEHVGAGMTLGELCHATITTSDNAAANLILATYGGP +QGLTSYARSLGDSVTRLDRWEPVMNEATPGDPRDTTSPRAMAQLLKTALLGDALSVSSRD +QLARWLEACETNGQRLKANLPAGWRMGSKTGTGARGSTNDVGIFWPPGRPPVLVTVYITN +TQAPPADRSGAIAAVARRVT--- +>[subseq from] Beta-lactamase class A n=1 Tax=Xenorhabdus mauleonii TaxID=351675 RepID=A0A1I3M8D5_9GAMM +--QIIAQLSALEKSANGRLGAVLIDTADHSTI-TYRANERFPLCSTSKLMVASAVLKQSE +KDESLLNKKVSYPQSALVEYSPITEKHLKEGMTLGELSAATLQYSDNTAMNLLLNQLGGP +HKVTEFARTIDDNHFRLDRKEPELNTAEPGDKRDTSTPQAMADSLYNLTLGNALASKQRA +QLVEWLKGNTTGSASIRAGVPADWVVGDKTGRGDYGTTNDIAVIWPDNKSPLILVTYFTQ +PSPEASARPDVLADAARIMTQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Rubrivivax sp. JA1026 TaxID=2710888 RepID=UPI0013E93BED +------AFGAIERSVAGRLGVYAYDLETGRSF-GHRQDERFPMCSTFKWLLAAAVLARVD +RGQERLERRIVFGREALLDYAPTTSRHADGAMTVAELCEAAVVLSDNTAANLLLQTLGGP +AGLTLWVRTLGDRTTRLDRREPDLNEARPGDERDTTTSAAMVLALRQALFGGGLSRRGAD +LLLQWMTASTTGLKRLRAGFPPGWLVADKTGTGAQGTTNDVAVVWAPGRAPLLLAAYLTE +SQAPIEAREAALARVAAR----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NWU49 TaxID=2201153 RepID=A0A2U3GXA9_9ACTN +------SLADLERAYGARIGVYAVATDTGATV-VHRADERFAFCSTFKSLAAAAVLHRNP +--LSRLDERVTYGRADLAAHSPVTERHVATGMTVRQLCDAAVRYSDNTAANLLLRDLGGP +RGLTTYLRGLGDRVSRLDHYEPELNRNPPGDPRDTTTPRAIAVDHRALVLGDALPAARRA +LLKDWLVRNTTGDRRIRAGVPRGWTVGDKTGTADWGRAHDVAVLWPPRAAPLVLAVLTEH +PDRGAAPSDPLIAEATRRT---- +>[subseq from] Beta-lactamase n=1 Tax=Legionella brunensis TaxID=29422 RepID=A0A0W0S039_9GAMM +--SLQGKLAELEASSGGRIGISAINTANDMRL-QYRAEERFPFCSTFKMMGVAAVLKKSM +MVSGLLQQRINYKKEDLIVYSPVTEKHLRDGMTIAELCIAAIQQSDNTAIDLLIKKLGGR +KAINVFAHSIGDLSFRLDRLEPELNSAIPGDVRDTSTPAAMEKSLQRLGLGNGLALPQRE +LLQTWLKGNTTGGARIRASVPKGWIVGDKTGTGDYGTTNDIAIIWPPKCPPIVVAIYFTQ +TKKDAAPNNEVIASATRLLLNTf +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas cucurbitae TaxID=56453 RepID=A0A2S7DSU2_9XANT +---LRAQWADIERGTGGRLGISLLDSATGWRL-GQRENERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQPVKIRASDMLEHAPVTKRHVGGALSVGDLCRATMIYSDNPAANRLFPLVGGP +PGVTAFLRGIGDAKTRSDRYEPEMNGFAPGEPRDTTTPVAMASTLRTLLLGAALQPASRK +QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG +AKVDDAARDAALKAVAVAVREW- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2A8HET7_9BACI +----NHSFVKLEKEYDDKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQRIKYTSKDFVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN +FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIASIWPPNKKPIILAILSNH +AKEDAKYDDKLIADATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. FJAT-20673 TaxID=1830326 RepID=UPI0009EF1C49 +--ATIKKFEQLEKEYDAKLGVYAIDTGTKKTV-EFHENERFAFTSTHKALAVGALLHQKS +--IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP +AGFKKALEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWAVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DEKEADYNDELIAEATEEVIK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F917_9BACT +-----------EDQLGARAPYIELDLNSGKILeSFRPEERFPMMSTFKILLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. GW101-3H11 TaxID=1813946 RepID=A0A165JRS1_9BURK +--AWNDALATIERSAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAALAGWMLALVD +QGRERLDARVHYAAADVVAYSPVSGPRAGNALTVGELCAATVSLSDNTAANVLMARHGGP +AGFTAFVRSLGDQVTRLDRTEPTLNEAAVGDPRDTTTPLAMLLTLQKLVLGDALSPASRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTSDSGTANDIGVLWPPGGAPVLVTCYLTR +STAPAEQRDAAIAQVARAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=A0A0M0G503_9BACI +-----ETFANIEDKYDARVGIYAIDTGSDRTI-DYRSEERFAFTSTYKALAAALVLKQNS +--MDELEEVITYTEDDLVSYSPITEKHVETGMTLAELSEAAVRTSDNTAGNLLFEELGGP +EQFQQSLREIGDDVTQSDRYETALNEFTPGNTRDTSTPAALATSLQGFAVGGLLPDDKRE +ILIDWMKGNATGDTLIRAGAPDGWTVADKSGAGRYGTRNDIAVVWAPDREPIIMAIMTRH +DTEDADYDDALIAEVAEVTLE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces alboverticillatus TaxID=173770 RepID=UPI000A3B5DD4 +---ICRRLSRLEREHSARVGVFAHNPRTGRTV-RYRADERFPMCSVFKTLAVAAVLRDLD +HDGTFLAKRVHYTQGDVDKWAPVTKDHIADGMTVAALCEATIQQSDNAAANLLLRELGGP +DAVTRFCRSVGDPVTRLDRWEPTLNSAEPWRVEDTTSPRAIGRTYARLVLGDALAPEDRE +RLTKWLLGNTTSTDRFRKALPPGWTLGDKTGAGSYGTNNDVGVAWSPDGSPLVLSVLTTK +HSPDAKGEDALVAETAKLLV--- +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T4B4_9BACT +------AAQQAETELNARVGLVIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VSDEDLKRQVPISQSDLVTYSPVTETWVGQDISLDALCDATLRTSDNTAANKVLEALGGP +DAVTAFMRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLIAAIYLTQ +TDASMEQRNAAIASIGTALAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. MUS 060 TaxID=1588031 RepID=UPI0005F2794A +--ALQQRLAEIERRSGGRLGVYLLDSGTGQRI-GRREQERFPLCSTFKFLLVAAVLQRVD +RGEVGLDQRVRVRAADVVSYAPVTKPHVGGTLSVDALCRAAMIFSDGGAANLLLRLVGDP +PGLTRFLRAHGDTQTRSDRNEPSMNGFALDDPRDTTTPAAMATTMRTLLLGDVLQPASRQ +RLIDWMIDNRTGEDCLRAGLPAGWKIGDKTGNNGSDSRNDIAIVWPPGRAPLLLTAYLNM +ATVDSDARDAALKAVAQAVVAWw +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=UPI0004C7D007 +--AFTGAFKKLEHAYDARLGVYAIDTGTGREV-AYRDGERFAYASTFKALAAGAVLRKYS +--LSGLDRVIRYAKDDLVDYSPVTEKHVKTGMTLGALCDAAVRYSDNTAANLLFDVLGGP +KGLDAMLEKMGDDVIQMENEEPELSRWVPGETHDTSTPRAMAEDLRAFVLGDALGKPERA +QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGNGSYGARNDIAVVWPPDSAPIVLAIMSWR +GDKDTPFDNKLIADAASVVTD-- +>[subseq from] BETA-LACTAMASE n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI0000112596 +------DFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFAPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVMK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDDCBCB +--EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD +KGEENLERRVVYEKEQLIAYSPEAEKHVGGEMSVGDLCKAAITLSDNTAANLILESLGGP +KELTNWLRTLGDGSTRLDRIEPDLNDIAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK +TLIEWLVANTTGNERLRTGLPETWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTN +ATVATAEINPVFGEVGRIVAE-- +>[subseq from] Beta-lactamase n=2 Tax=Pseudovibrio sp. WM33 TaxID=1735585 RepID=A0A166F5K1_9RHOB +-----DTVGQLETEVGGRIGVVLRHTGSDWTV-EHRADERFPMASTFKALLCGAVLSRVD +RGEENLGDLVTYKATELVSYSPVTENHVASGMSVGQLCEATVTMSDNSAANLLLKRVDGP +EGLTRFLRGLGDRVTRLDRNEPAMNEARHGDPRDTTSPSAVLKTLDRLLFEDVLLPSSRA +QLQQWMVDDKVADELIRKHLPKGWRIADKSGGGQNGSRGIISVIWPDAGAPYLASVYMMG +SDASFRQRNAVIAEIGKAMIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNQ766 TaxID=1169157 RepID=UPI0003622F58 +-----RELAALEREYDARLGVYAVDTGSGREV-AYRAGERFPYASTFKALAAGVVLRTHS +--ARELDEVVTYSADDLIAHSPVTGEHVGTGMTLRDLCEAAVRYSDNAAANLVLAELGGP +AGMDAELEALGDDVTRMVRDEPELSRWHPDDTRDTSTPRALAGDLRALVLDDALDKRDRA +RLTEWLRTNTTGDTLIRAGVPETWRVGDKTGTGSYGARNDIAVLWPPDRAPIVLAIMTNR +TQRDAEPDDALLADAASAVA--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus megaterium (strain ATCC 14581 / DSM 32 / JCM 2506 / NBRC 15308 / NCIMB 9376 / NCTC 10342 / VKM B-512) TaxID=1348623 RepID=A0A5B7WKA7_BACMB +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQKYVLGQALPEDKRA +LLTDLMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. (strain JS42) TaxID=232721 RepID=A1W8B5_ACISJ +-qQLQAALGRVERRVGGRLGVAVLDTGSDALA-TYRGDERFALCSTFKLLLAGQVLQRAD +QGLERLDARVRYGREDLVEYSPRTEPHAGGAMTVAELCEATMVLSDNSAANLLLRRQGGP +AGLTAWLRTLGDAHTRLDRIEPALNDVPAGELRDTTTPRAMVHTVQKLVLGDALSGEARA +RLQGWLLGNLTGDKRLRAGMPAGWRIGEKTGTAN-GTSNDVGVVWPEGGAPAVVACYLTQ +CPAAPAQRDAAIAEVGSLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces acidiscabies TaxID=42234 RepID=A0A1Q2Z267_9ACTN +-aATRDVFAGLEQEYAARLGVFAHDTATGRTL-THRADERFPMCSVFKAPAAAAVLREGV +----DLTRRIHYTQQELTDYAPVTEKHLDTGMTVEELCAAAVSHSDNAAANFLLRELGGP +TAITRFARSLGDSVTRLDRWEPDLNSAEPWRKTDTTTPHAIARTYAKFLLGDVLPPADRT +RLTSWMVANSTNVTRFRAGLPADWILADKTGGGSYGVANDVGVVWPPGRPPLVIAVLTTT +YAAEGPSKNELVARAAELVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=H9AXL9_ACIBA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAHLFLTTIGGP +KELTAFLHNMGDHVTRLDCWGPKLTEAIPHDERDTTMPAAVANTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPILRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Agaribacter marinus TaxID=1431249 RepID=UPI0013AE27BC +--DIKATFSKLEKEFDARLGVFALDTGTNKTI-AYRSEERFAYASTHKALAVGALLQQKS +--MEDLEQRITYTKDDLVNYNPITEKHVDTGMTLKELSDASIRFSDNTAANLIFNQIGGP +SGLKDTLRGLGDEVTNPQRKEPALNEFTPGETADTSTPKALVTSLQAFTLGDVLPEEKRT +ILVDWLKRNTTGDNLIRAGVPSNWEVADKTGAASYGTRNDIAIIWPTKVDPIVLAILSDR +DKEDADYNDKLIAQATKKVIE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. BK251 TaxID=2512125 RepID=A0A4R1SBX6_9RHIZ +--DVDQQLAELEKRTGGRLGVSVFDTETNITL-GYRETERFAICSTYKALAAALILQKVD +KGEESLERRIVFDKEALVTYSPITEKQTGGEMTLAEVCEAAVTLSDNTAGNLLLESLDGP +QGFTKRLRTIGDASTRLDRTETALNEAKKDDPRDTTTPDAMLDTLGNLAIGTVLSEASRE +RLTGWLVSNRTGDARLRAGIPKEWKVGDKTGTGRNGAAADIAVVWPPGRGPILVTTYVAE +ATVPIDQVNPVFAEVGRIVA--- +>[subseq from] Beta-lactamase n=2 Tax=Paenibacillus polymyxa TaxID=1406 RepID=A0A074LC95_PAEPO +-----VVFKQLETKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS +--NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP +EGFEKAMRDNGDTVVMANRYETELNEAIPGDHRDTSTPNALANSFKVLTIDDSMPNDKQE +LLIGWLKENTTGDKLIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDRKPIIIAVMSSR +DTEDAEYNNALIAEAAKAAFK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. IBTA2 TaxID=2283625 RepID=UPI00103E5CB6 +---TDRAFAELERKFDARLGVYVVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS +--LPQMERLVRYGQEEIISHSPITEKHVDTGMTLRELCDATIRYSDNAAANILFRELGGP +RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAVVWPPGAAPIAIAVLSRR +DVKDAEPDDALIAGAAEVALEAf +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Acidisoma TaxID=2634065 RepID=UPI00131A6FC7 +--AMTERLAAIETASDGRLGVAIADMGSGSLL-GYRAAERFPLCSVYKLLAAAAVLALVD +AGKADLDRRIVYGRHAVLDGSPVTLKHIGGKLSLAHLCDAAVTRSDNTAGNLLLSFLGGP +AALTAYIRSIGDDATRVDRGEPDVNQATPGDPKDTTVPAAMLSDLLAFLQGNKLSAPSRA +QLMTWMRGCKTGSGRLEAGLPKGWHIGDKTGSGGYGTTNDVGIVWPSSGAPILVAAFLTD +TTVPAARRNAALAAVGAIV---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces globisporus TaxID=1908 RepID=UPI0004C86604 +-----GDFKELERKFDARLGVYAIDTGTGHEV-IHNDRGRFAYNSTFKALQAAVVLSTYS +--LDGLDKRVTYTREDLVANSPVTEKHVDGGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDAAPIVIAILSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. MB95 TaxID=671602 RepID=UPI0013F6256A +---SDREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR +TEKDAEYHDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MMG1522 TaxID=1415545 RepID=A0A0M8T3M7_9ACTN +----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLDKYS +--LDGLDRRVTYTRKDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLGEALPAPERE +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR +ATKDAEPSDELIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Kushneria avicenniae TaxID=402385 RepID=A0A1I1N2L2_9GAMM +-kAVQRKLQALEEQHGGRLGVALMNVGTGAVV-SHRGDERFLFNSTGKVFMAAAVLARVD +SGEESLDRRLEIKASDIGEWAPVTEPHVGGPMTLAELCQAAMAWSDNTAANKLIESVGGP +EPITAYLRRIGDDTTRLDRWEPELNTDHEGDERDTTTPLAMMQTLRTLLLGDALSPSSRH +QLAAWMIEGKTGDARLRAGMPPGWLIGEKTGTNSVGNANDVGIAWPADRGAVIAVAYTWL +PKASKTQRDEVIAEIGRLAA--- +>[subseq from] Class A beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A5Q0DAG0_BACME +---SDREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR +TEKDAEYHDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. WMMB 322 TaxID=1286821 RepID=A0A1C6PZZ7_9ACTN +--ATTRRLKKLEREHDARLGVFAHNTGTGTTV-VHRAGERFPMCSTFKPLAAAAVMKARD +GGGSSLDERIRYSRSDLVEHSPVTGTHLAGGMTLRELCDAAVRYSDNTAANLLLRELGGP +TAVTRFCRSLGDEVTRLDRWETELNSAEPGNVKDTTSPRAIGRTYMRLILGDTLGGAGRR +RLADWLKRNTTGEESLRAGLPEGWSVGEKTGAGGYGTHNDVGVAWTAHGEPVVLAVLTTK +KSAGAEPDRALIAKTARILA--- +>[subseq from] Beta-lactamase n=1 Tax=Yonghaparkia sp. Root332 TaxID=1736516 RepID=A0A0Q6R8A6_9MICO +--DLDDDLADLEGEYDARVGVYAVDTGSGETV-AYREDERFAYASTFKALLAAVVLKTVD +----DLDRVITYSADELVDYSPVTEQNVDGGMSIRELAEATVRTSDNSAANLLLDELGGP +AGFADALTRVGDRTTQPERRETELNTAVPGETRDTSTPRALAETLRGFALDGLLDDTQAA +TLIDWMSGNATGDPLIRAGAPEGWAVADKSGAGGYGTRNDLGIVWPPDGDPIVIAVLTTR +DAADAEYDNALVADVAAVVLE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia dabaoshanensis TaxID=564714 RepID=A0A2N7VYI7_9BURK +--AIEAELVSIEKGIGARLGVAIHDIETGLRA-GHRANERFPMCSTFKLMLAASVLARVD +RREESLERRIVFGEDRLETYAPVTRAHTGAPMTIAELCDAAVTMTDSAAANLLLDTIGGP +PGFTAYMRRLGDTVTRLDRTEPTLNTAIAGDARDTTTPLAMLGSMRDVLLGDALSSASRA +QLLAWAVGNRVGDARLRAGVPRDWRVADKTGTGEHGTTNDIGILWPQASAPVLVTVYLTG +TQAPTRAREAAIAGVARTIVRH- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura bangladeshensis TaxID=453573 RepID=UPI0013D03A30 +--DVTKRLTRLERSRHARIGAFAIDTGTGRTV-SHRADETFPFASTFKAMACGAVLRKAR +QAPGLLDKVIRYTEADLVDYSPVTEKHVGTGMTVADLCHAAITQSDNTAGNLVLRQIGGP +AGLTAFLRSLGDRVSRSDRWETALNDWRPGERRDTTAPRPWANDLRALTAGNALVPADRE +RLVGWMKATVTGDKRIRAGLPKSWTVGDKTGTGGYGTANDIAIAYPKNGAPLIIVITTNK +RTPDAEADDTAVARTAGILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus polymyxa TaxID=1406 RepID=UPI00069404FF +-----VVFKQLEVKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS +--NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP +EGFEKAMRDNGDTVVMANRYETELNEAIPGDHRDTSTPNALANSLKLLTIDDSMPNDKQE +LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR +DTKDAEYNNALIAEAAKAAFK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. OK885 TaxID=1882770 RepID=UPI000C70C0FD +hrDTRTRLRELEARHGARIGAFAYNLRTKATV-RHRAAERFPICSVFKTLAAAAVLRDLD +RHGETLARRIHYTVADLAGYSPKTGEHLAGGMTVGELCGAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PAQDAAADSPLVAATASVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis dassonvillei TaxID=2014 RepID=UPI00076E4171 +--ELTREFERLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYASTHKALTAALVLQQNT +--PEEMEEVVTFTEDDLVDYSPITEQHVDTGMTLTEVADAAVRHSDNTAANLLFEELGGP +DAFEDALREIGDDVTDPERIETELNAWTPGDTSDTSTPRAMAGSLREFTLGDALPEDRRE +VLNDMLVNNTTGDELIRAGVPEDWRVGDKTGAGSHGTRNDIAVLWPTEGDPIVLAVMSSR +EAEDAEYDDALIARAAEVVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura darangshiensis TaxID=705336 RepID=A0A4R5BXM9_9ACTN +--EVTKQIARLEATHHERIGAFAIDTGTGRSV-SHRPDESFPFASTFKAMACGAVLRKAR +EDPGLLDRVIHYTKDDLVDYSPVTEKHVDTGMTVADLCHAGITQSDNTAGNLVLKQIGGP +AGLTAFLRSIGDRVSRSDRWETALNDWKPGEQRDTTAPRPWAGDLRALTVGGVLVPADRK +RLIDWMKATVTGDERIRAGLPKSWTVGDKTGTGGYGTANDIAIAYPKSGAPLIIVITTNK +PAPDADPDDKAIAQTARVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=UPI000786581B +--AFTGAFKKLEHAYDARLGVYAIDTGTGREV-AYRDGERFAYASTFKALAAGAVLRKYS +--LSGLDRVIRYAKDDLVDYSPVTEKHVKTGMTLGALCDAAVRYSDNTAANLLFDVLGGP +KGLDAMLEKMGDDVIQMENEEPELSRWVPGETHDTSTPRAMAEDLRAFVLGDALGKPERA +QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGNGSYGARNDIAVVWPPDSAPIVLAIMSWR +GDKDTTFDNKLIADAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium yuanmingense TaxID=108015 RepID=UPI0004B0365B +-----SEFESYERESGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAANVLARVD +RGEEQLAAMIRYGQADLLEYAPVAREHLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSQPGDPRDTTTPAAMAGNLRRLVAGEALSPASRA +LLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYTQG +GTPSAAQITSAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. Root147 TaxID=1736468 RepID=A0A0Q9GH75_9BACI +---SDREFAKLEDKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGTLLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLREIADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPEDKRA +LLTDWMKRNTTGDALIREGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas hortorum TaxID=56454 RepID=UPI000BAAB17C +----GARWAEIERGTGGRLGIGLLDSAIGKHF-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP +QGLTAFLRGIGDTQTRSDRHEPEMNQFAAGDPRDTTTPAAMALTLRTLLLGDALQPASRK +QLSDWMIDNRTGDTCLRAGLPRSWKIGDKTGSNGIDTRNDIAILWPPKGAPLLLTTYLNG +ASVDSDARDAALKAVAHAVASY- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI0009E25DD6 +-----KKLEQLEKEYDAKLGVYAIDTGTKKTV-EFHENERFAFTSTHKALAVGALLHQKS +--IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP +AEFKKILEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DEKEADYNDELIADATEEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. LMG 12461 TaxID=2014543 RepID=UPI00126556A1 +--TLQLRLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD +RGELALERRVPVRKADLLANAPVSERHVGGTLSVVELCRAAMIYSDNTAANLLLPLVGDP +PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPRDTTTPAAMAATMRALLLGDVLQPVSRQ +RLIAWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG +ATVDSAARDATLKAVAQAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI00096E2B68 +--MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLMQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP +PGLTRFLRGIGDTKTRSDRLEPQMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAGRDAALKAVAEAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI000FEC8740 +----------------RSLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD +KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP +AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD +RLIAWLVTSTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE +TTVPVKELNPLFAEVGRMIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albulus TaxID=68570 RepID=UPI0005C92A77 +--SFESELQELERRYAARLGVYARNARTGQVV-AHRARERFAMCSTFKTVAAAAILRDHA +-RCAPLDKVIHYPPADLLANSPRTAEHVDTGMAVGDLCAAAIQYSDNTAANLLLRQIGGP +AGLTRFFRSIGDRESRLDRWETELNDAVPGDLRDTTTPEALGTSYGRLTVGRALDPAARE +HLVTWLKGNTTSGERFRAGLPHDWVVGDKTGTGDYASANDVGVAWTTRQTPIVLAVLTSK +DAKDAPVDNALIADAARIVAR-- +>[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A141R9Y8_9BACT +-tALTQKLAALEKSTGGRLGVAWID-GDGLRY-GYRADERFPMTSTFKTLAAAAILHNSV +SQPNLLEKKIRIREADRVAWTPVTGNYFGKEMSIAALCAAAIEYSDNLAANYLLKELGGP +QGVTAYARLLGDTLTRLDRQETELNSAAPGDERDTSTPAAMAENLSKLTLGDALPTAQRQ +RLISWLKQNTTGDQSIRAGVPAGWTVGDKTGAGAYGTTNDLAILWPEKGAPKILAIYFTQ +PQPDAANNKAVLASATRLAID-- +>[subseq from] Beta-lactamase n=1 Tax=[Brevibacterium] frigoritolerans TaxID=450367 RepID=A0A4Y8U1K3_9BACI +--ATIKKFEQLEKEYDAKLGVYAIDTGTKETV-EFHENERFAFTSTHKALAVGALLQQKS +--IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP +AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DEKEADYNDELIAEATEEVIK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 6-11-2 TaxID=2585753 RepID=A0A4Y4KBY0_9ACTN +---TTARLRALEQGHGARLGVFAHNPATGRTV-RYRADERFPMCSVFKTLAAAAVLRDLD +RHGKVLSRRVHYTEADLVLGSDQTRAHLATGMTIAELADVAIRFSDNTAGNLLLRELGGP +TAVTRFARSLGDPVTRLDRWEPDLNTAEPWRLTDTTSPRAIGRTYARLVLGDALNRDDRR +LLTRWLLNNTTSANRFRAGLPPTWTVADKTGSGAHGTTNDVGVAWTRSGSPVVLAVLSTK +PARDAPYDDALVARTAAAVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID5643 TaxID=2690307 RepID=UPI00136D5A97 +--SVTARLRELEREHTARLGVYARNMRTGRTV-AHRADELFPMASVFKTLAAAAVLRDLD +RDGEFLARRVHYTQEYVTTYSPITEDHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP +TAITRFARSVGDRVTRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGSALARGDRA +RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNHDVGITWPPDGPPIVMSVLTTQ +PEEDAPADNPLVAGAAALLA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8GCG1_9BACI +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIADATKIALN-- +>[subseq from] Beta-lactamase n=1 Tax=Salinisphaera orenii MK-B5 TaxID=856730 RepID=A0A423PGH8_9GAMM +--AFHAEIADLEKRHGGRLGVAVRDTAGEQRV-AHRADERFLMCSTLKFPLAGLILSRVD +AGEESLDRHITYDAGDVVTYSPETGRHVGTGMTLGAVCRAGLTLSDNTAANLMLRSVGGP +AALTAFVRALGDTVTRSDRYETALNAYTPGSDHDTTSPSAMGHLMQRLLLDDVLSAPSRG +QLTRWLIANETGDHRLRAGMPGHWRIGDKTGSGGNNTANDIAIVWPQPDAPVIVSAYYAG +SDAGRSQRDRVLADVGRATV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. ZEA17I TaxID=2202516 RepID=A0A2V2QMH4_9ACTN +---TDRAFAELERAFDARLGVYAVDTGDGRTV-THRPDERFAYASTCKALLAGAVLARKT +--LPQMERLVRYGQEEIISHSPITAKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP +RGLQDALRGIGDDVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LITDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR +DVKDAEPDDALIAGAARVALEAf +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas alkaliantarctica TaxID=232346 RepID=UPI0004AB29E0 +--SITAELGRIEHALDARIGFAAHHLATGQRW-EVNANERFAMSSTFKTLACGALLAQVD +EGQLALDTEVSFEESELVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLVLQALGGP +ESITAFARSMDDPVTRLDRFETELNEATPGDERDTTTPNAMLATLEKLVLGEVLSGESRQ +QLEDWMKGNAVADSLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQVPMVVVFYITE +TEASFDARNAAIASLGKVIQ--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF668C2 +-----HSFVKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQIYALSDILPIEKRS +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8W7_9BACT +-----------EDQLGARVRYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVSRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +GQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=4 Tax=Streptomyces TaxID=1883 RepID=A0A2P5JHB5_STRGR +------DFKKLERKFDARLGVYAIDTGTGREV-AHNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIKAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKEAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2B2Z6N2_BACME +---SDREFAKLEDKYDANLGVFALDTGTNKTV-TYHPDERFAYVSTHKALAVGALLQRKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. GFAJ-1 TaxID=1118153 RepID=H0J5M4_9GAMM +---VRAELQRIEQELEARIGFAAHNFATGQRW-EVNADERFAMSSTFKTLACGALLAQVD +EGQLALDTEVSFAASELVTYSPVTEQYAGQQMTLFELCDATMTTSDNTAANLVLEALGGP +EAVTAFARSMDDSTTRLDRFETELNEATPGDKRDTTTPNAMLATLEKLVLGDVLTPESRQ +QLETWMKGNAVADGLFRAAMP-DWAIADRTGAGGYGSRSITAIIWPPEQAPTVVVFYITE +TEASFEARNAAIASLGEVIQ--- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. Leaf76 TaxID=1736236 RepID=A0A0S9F4L1_9BURK +--AWNDTLAGIERSAQGRLGVAMLDTGTGLAL-GWRQDERFAMASTFKAVLAGWMLALVD +QGKERLDARVHYAAADVVAYSPASGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP +AGLTAFVRSLGDGITRLDRTEPTLNEAKVGDPRDTTTPLAMLQTLQKLVLGDVLTPGSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTTDSGTSNDIAVMWPPGGAPVVVTCYVTA +STASAEQRDAAIAQVARAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Yonghaparkia sp. Soil809 TaxID=1736417 RepID=UPI0006FB88D2 +--DLDDDLADLEGEYDARVGVYAVDTGSGETV-AYREDERFAYASTFKALLAAVVLKTVD +----DLDRVITYSADELVDYSPVTEQNVDGGMSIRELAEATVRTSDNSAANLLLDELGGP +AGFADALTRVGDRTTQPERRETELNTAVPGETRDTSTPRALAETLRGFALDGLLDDTQAA +TLIDWMSGNATGDPLIRAGAPEGWAVADKSGAGGYGTRNDLGIVWPPDGDPIVIAVLTTR +DAADAEYDNALVADVAAVVLE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0H4IUV1_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPA-------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI00064F9824 +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR +TEKDAEYHDKLIAEAAKQAVK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Halomonas sp. TaxID=1486246 RepID=A0A651D624_HALSX +---VRKELQRIEQELEARIGFAAHDLATGQRW-EVNADQRFAMSSTFKTLACGALLQRVD +NGQEQLETEVSFSSSDLVTHSPVTEQYADQQMSLFELCEATMTTSDNTAANLVLQALGGP +ETITQFASSLGDPITRLDRWETELNEAQPGDERDTTTPNAMLANLEQLVLGDVLSPDAKR +QLQEWMIGNAVADGLFRAAMPSDWVIADRTGAGGFGSRSITAIIWPPEREPMVVAFYITE +TDASFEDRNAAIASLGRVIQ--- +>[subseq from] class A beta-lactamase n=1 Tax=Kribbella catacumbae TaxID=460086 RepID=UPI00058B82A9 +------AFAVLEKQYSARLGVFALDTGTNRTI-TYRADERFAFASTFKAHACGVLLAQDK +----DLDKLIRYSASDLVANSPITEKHVRTGMTLRQLCDATIRYSDNAAANLILTELGGP +SGFQAGLRKLGDTVTRSDRDEPELSEGKPGDLRDTTTPRALSTTLQKLTLGEALPPAKRA +LLIGWLQTNTTGDKLIRAGAPKTWKIGDKTGSAGYGGRNDVAILWPPNHAPIMLAVMSTK +GVKDAKREDALIAAAAKATL--- +>[subseq from] Beta-lactamase SHV-6 (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=BLA6_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARATTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERN-------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=bacterium FRT-Slr-16 TaxID=1564894 RepID=A0A097SRS7_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQ--------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. Akac8 TaxID=2563106 RepID=A0A4S3GGY5_9ACTN +------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDHRP +--GARLDERIPYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAGNLLLRDIGGP +RGLTAYARRLGDRVTRLDHTEPELNGNPPGDPRDTTTPRAIAADYRALVLGDALPAAGRT +LLTDWLVRNTTGDRRIRAAAPRGWRVGDKTGGGEYGRGNDVAVLWPGGRPPLVLSVLTER +PGRAATPSDELVAEAARRVLD-- +>[subseq from] Beta-lactamase n=3 Tax=Stenotrophomonas TaxID=40323 RepID=A0A4S2D9G3_STEMA +-----PDFAALEAASGGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKFVLCAAVLRQVD +AGRLDLDKRVPMRAEDLIDHAPVTRRHIGKDLTVRDLCRATMITSDNPAANLLLGVVGGP +PAVTRFLREHGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRFLLGQVLAPASRQ +QLADWLIDNETGDERLRAGLGSTWRVGDKTGSNGKDTTNDIAMLWPMGGTPWVLTSYLQG +ATVDDAGRNDVLRQVAV------ +>[subseq from] class A beta-lactamase n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=UPI000DEF34BB +---TARQLAELERNAGGRIGVFAQEVDSGRSL-AYRANDRFPMCSTFKLLLVGALLQRSA +TQPDLLYRHVSYRREQLIDYSPIAEQYVEQGMSVKDLCDAAMRFSDNTAANLLLEELGGP +QEVNRFARSLGDGLTRLDRIEPELNRAEPDDPRDTTTPAAMTANLHALLFSPLLPERQRG +LLNDWLLGNTTGNLRIRAGLPAEWRVGDKTGSGGHGAANDVAVAWRPGKSPLLLSVFYWG +SPAMMDERNAVIAAVARVAAAEf +>[subseq from] class A beta-lactamase n=1 Tax=Franconibacter pulveris TaxID=435910 RepID=UPI0004A2E649 +--QLTAAAQQEEKTLNARIGVAVLDTATGKTA-SYRGDERFPLNSTHKALLCGALLKQAD +EKKVSLTEAVRFDKSRLVEYSPVTEKHTAPQMNWLQLCSAAVSYSDNTAANLISQKVGGP +QGVNAFLRANGDKTTRLDRVEPALNEARPGDERDTTTPQAISRTLQTLLLGDALSEASRK +QLTRWMIDDKVADALLRQSLPKGWTIADKTGAGGYGSRSIISMVWPEKGAPLVVAIYITQ +TDASLSQSNAAIARLGHVIFQQ- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia nova TaxID=37330 RepID=A0A2T2ZEY9_9NOCA +-----AEFHDLEARLHGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP +--PAELDRRITYTRADLVPNSPVTEQHVDQGLTVREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRTIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPAVAADDRD +VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGDYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDAEYDNAAITRAATIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF8CB77 +---SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALVSSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGEPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CS147 TaxID=2162715 RepID=A0A2T7LH20_9ACTN +------DFKKLERAFDARLGVYAIDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +GGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAVIRAGVPENWAVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAKPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=A0A0M1KKT2_9XANT +--MLRAQWAEIERGTGGRLGIDLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP +AGLTGFLRGIGDAQTRSDRYEPETNRFAAGDPRDTTTPAAMVATLRTLLLGDALQPSSRQ +QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGSDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter sp. Bisph1 TaxID=1274399 RepID=UPI00057BFD8B +----------QEERLGARIGIAVIDTGSGETV-SYRGDERFPMTSTHKALLCGALLSKVD +KGEFTLSDTTQFSQQDLVEYSPVTSKFVAPAMSWQQLCSAAITVSDNTAANVVAKKIGGP +AALTRFVADNGDTVTRLDRAEPELNSAIPGDLRDTTTPLAISHSLQKMALGEILTPASRA +QLVQWMQDDKVADALLRASLPKGWKIGDKTGAGEHGTRSIISIVWPKKGAPRIVSVYVTN +TQATMAQSNDAIARIGKAIFS-- +>[subseq from] Beta-lactamase n=1 Tax=Gracilibacillus dipsosauri TaxID=178340 RepID=A0A317L3B1_9BACI +----DEKFAQLENEFNVQLGVYAMDTGTNQTV-EYRPEERFAYSSTFKPLAAAILLEQNN +--IEDLEKIVTYTKDDLVTYSPVTEKHVDTGMTLLEISEAAIRKSDNTAGNLLLEALGGP +DKFEQALRDIGDDITQPERYETELNEFIPGNNRDTSTPRAMATNLKKVTLDDFLSDDKRE +LLIDWMKGNATGDALIRAGAPEGWIVGDKSGAGSYGTRNDVAIVWPPNREPIVMAIMSRH +DTENAEYDDALIAKAAEITL--- +>[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus bovienii TaxID=40576 RepID=A0A0B6X686_XENBV +-nQITNQLSALEKNANGRLGVVLIDTADHSII-TYRGHERFPLCSTSKMMTVSALLKKSE +TDKDLLNQRIHYQQSDIVEYSPITEKHLKDGMTLAELSAATIQYSDNTAMNLLLDQLGGA +HSVTRFARSIGDNAFRLDRKEPELNMVTPGDERDTTTPQAMADSLYKLALGNTLAATQRT +QLVEWLKGNTTGGTSISAGVPDNWIVGDKTGRCDYGSTNDIAVIWPDDKAPLILVTYFTQ +PSKDAKAHNDVLAAAARIMTQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. f51 TaxID=1827742 RepID=UPI000BF0EAFB +------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +EGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPGSAPIVIAILSHR +GTKDAEPDDRLIAEAASVVVE-- +>[subseq from] Beta-lactamase n=3 Tax=Streptomyces TaxID=1883 RepID=A0A4Z0VRI9_9ACTN +--KARRAFVRLERKFDARLGVYALDTGSRRSI-AHRADERFAYCSTCKAFLAGTVLKRNS +--LREMERRVRVRPQDLEGYSPIARKHVGSTMSLRELCDAAVRYSDNAAANLLFRELGGP +KGLQDALRDIGDRVTRADRYEVELSEGTPGDSRDTSTPRALVTDLRAFVLGDVLPGRKRE +VLTDWLKRNTTGDKLIRAGAPRGWEVGDKTGNGGYGTRNDIAVLWPPKGDPITLAIMSRR +DTRDAEHDDALIAEAAEVAL--- +>[subseq from] Beta-lactamase (Penicillinase) n=1 Tax=Xenorhabdus bovienii str. feltiae Moldova TaxID=1398200 RepID=A0A077NUE4_XENBV +-nQITNQLSALEKNANGRLGVVLIDTADHSII-TYRGHERFPLCSTSKMMTVSALLKKSE +TDKDLLNQRIHYQQSDIVEYSPITEKHLKDGMTLAELSAATIQYSDNTAMNLLLDQLGGA +HSVTRFARSIGDNAFRLDRKEPELNMVTPGDERDTTTPQAMADSLYKLALGNTLAATQRT +QLVEWLKGNTTGGTSISAGVPDNWIVGDKTGRCDYGSTNDIAVIWPDDKAPLILVTYFTQ +PSKDAKAHNDVLAAAARIMTQ-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium yuanmingense TaxID=108015 RepID=A0A1C3URT4_9BRAD +-----SEFESYERESGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAASVLARVD +RGEEQLAAMIRYGQADLLEYAPVAREHLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSQPGDPRDTTTPAAMAGNLRRLVAGEALSPASRA +LLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYTQG +GTPSAAQITSAFARIGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CFMR 7 TaxID=1649184 RepID=UPI0011A192D1 +---TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS +--LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANILFRELGGP +RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR +DVKDAEPDDALIAGAAEVALEAf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CFMR 7 TaxID=1649184 RepID=A0A0M3QKW1_9ACTN +---TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS +--LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANILFRELGGP +RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR +DVKDAEPDDALIAGAAEVALEAf +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI001369A71B +---TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS +--LPQMERLVRYGQEEIISHSPITEKHVDTGMTLRELCDATIRYSDNAAANILFRELGGP +RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR +DVKDAEPDDALIAGAAEVALEAf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI000D02B67A +----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +NGFEKSLKQIGDHVTKSNRFETDLNSAIPGDIRDTSTAKALATDLKAYTLDNTLTSDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVALN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces violaceusniger (strain Tu 4113) TaxID=653045 RepID=G2P477_STRV4 +-----GEFKKLERSYDARLGVYAIDTGTGHEV-AYRDGERFGYASTFKALEAGAVLQKVK +--LGGLDRVIKYSEDDLIDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDELGGP +KGLDATLEKMGDDVIQMERREPELSRWVPGSTRDTSTPRAMAKDLRAFVLGDVLGDGERA +QLTKWLRTNTTGDALIRAGVPKDWQVGDKTGSGSYGGRNDIAVVWPPDSAPIVVAIMSNR +GDKDATSDDKLIADAAHVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium dankookense TaxID=560405 RepID=A0A564FTZ7_9RHIZ +-eDAQARLLALARGFSGRLGVAARDTGSGRGL-AHAADERFPLCSTFKLLAAAALLARVE +RGTETLSRAMPYTAADLDSYAPVARRRLEAGMPLGEACAAALVWSDNTATNLVLRALGGP +EALTAWLRQIGDAKTRLDRWEPELNTAIPGDPRDTTTPAAMLATLELVLLGPVLTPESRA +RLAGWMMESRTGLKRLRAGIPATWTVGDKTGSGANGTANVVAIVRPPGRAPLLAAVYITQ +TDAPEAVRDSIHAEVGRLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus polymyxa TaxID=1406 RepID=UPI0007EB009C +---VNVVFKQLETKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS +--NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP +KGFEKAMRDNGDTVVMANRYETELNEANPGDHRDTSTPNALANSLKVLTIDDSMPNDKQE +LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR +DTKDAEYNNALIAEAAKAAFK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. gb14 TaxID=1827753 RepID=UPI000BF13935 +------DFKQLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVANSPVTEKHIDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +EGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPDDRLIAEAASVVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A242ZD07_9BACI +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNELQPDDTRDTSTAMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIADATKIALN-- +>[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. 1_2014MBL_MicDiv TaxID=1644131 RepID=A0A1I9Y1G5_9BURK +--TAETQLAALEQAAGGRLGVAAWRHGSDVRV-AHRADERFPLASTFKAMLAAAVLARSV +SQPGLLEQHVRYEKKELVTYSPITEKHLADGMSVAKLCAATLQYSDNSAANFLMKILGGP +QAVTAYARSIGNTLFQLERWETELNSAIPGEVRDTASPASMAHSLQQVLLGNSLPAPQRQ +QLDAWMRGNTTGDKRIRAGVPAGWHVADKTGSGAYGSVNDIGVAYPASGAPLLIAVYYTR +EQKNAPTNQDIITAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia cerradoensis TaxID=85688 RepID=A0A231HCU7_9NOCA +----LAEFRDLEARLHGRLGVYALDTGTGRAV-EYRPDERFPYCSTFKALAAGALLSTLP +--PAELDRRVTYTRADLLPNSPVTEQHVDQGMTLREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRAIGDSTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPSVAADDRD +VLTGLLRANTTGAALIRAGVPAGWQVGDKTGAGDYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDAEYDNAAIARAATIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. LMG 12460 TaxID=1591132 RepID=UPI00126411F4 +--TLQLQLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD +RGELALERRVPVRKADLLANAPVSERHVGGTLSVAELCRAAMIYSDNTAANLLLPLVGDP +PGVTRFLRALGDASTQLDRNEPGMNEFVAGDPRDTTTPAAMAGTMRALLLGEVLQPVSRQ +RLIAWMRDNRTGNDCLRAGLPAGWQIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG +ATVDSAARDATLKAVAQAVVA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Dyella sp. LLH-Slr-21 TaxID=1564813 RepID=A0A097SRR1_9GAMM +--ETLVKVKDAEDQWGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRLHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQAT------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Nitratireductor soli TaxID=1670619 RepID=UPI000B3D76A4 +-dALARKLVEMEKRLGARLGASITDTHTGRRW-LQRADERFPMNSTFKAFACAAVLARVD +AGEETLEREIAIRKSDLVNYSPVTEKRVGGRMKLFELCEAASTMSDNTAANLLVDSLGGP +QGWTRFMRSIGDGVSRLDRKEPGLTTATPGDPRDTTTPEAIAASLRTLVFGDVLASASRR +QFETWLIDNKVSRPLLRAGLPGDWRIADRTGAGGHGSRGIVAVIWPPARQPVIAAIYIAE +CKQPMDQRNAAIAEIGRTLAE-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillaceae TaxID=186817 RepID=A0A024P8A8_9BACI +--NASEKFSQLENEYNARLGVYAIDTGSNQTI-GYRPEERFAFTSTYKALAAAIVLQQST +--MKELKEVITYTEDDLVSYSPITEKHVDTGMTLLKLAEAAVRSSDNTAGNLLFKGLGGP +DGFEQALRQIGDNTTQSERYEPDLNEFTPGDNRDTSTPKALTTDLQAFAVGDLLSDDERE +RFTNWLQGNATGDTLIRAGAPEGWKVGDKSGAGSYGTRNDIAVVWPPNREPIIISIMSRH +YTEEAKYDDALIAQAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonosporaceae bacterium KJ-029 TaxID=2494575 RepID=UPI0010F9F9D2 +------DFAPLEREFDARLGVYAVDTGTGRTV-AHRPDERFAYASTFKALAAAAVLDVTS +--AAELDQVVTYTRDELVSHSPITGKHVESGMTLRAIADAAVRYSDNTAGNLLLSRLGGP +AGLKQRLRDIGDEVTEPARLEVELNAAVPGDVRDTSTPRALATSLRAYAVDDALSSEDRA +VLVDWLKRNTTGDKLIRAGSPDGWEVGDKTGAGGYGTRNDIAVLWPPDRPPIVLAVLSSR +DEKDAEPDDSLVARAAELTL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000D042816 +----NQSFAKLEKEYDAKLGIYALDTDTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKLE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces pseudovenezuelae TaxID=67350 RepID=A0A101NCV5_9ACTN +--DVTARLRALEERYDARLGVFAHRLSTGRSV-RYRADELFPMCSVFKALAAAAVLRDLD +RHGEVLARRIHYTADDLVMGSDRTKEHLAEGMTIAELADVAITYSDNTAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWEPELNTAEPWRRTDTTSPYAVGRTYGRLVLGDALNRRDRE +LLTHWLLNNTTSVNRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTDAGDPIVLSVLSTM +PAQDAVRDDALVADAARAVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Yonghaparkia sp. Root332 TaxID=1736516 RepID=UPI0009E9030D +--DLDDDLADLEGEYDARVGVYAVDTGSGETV-AYREDERFAYASTFKALLAAVVLKTVD +----DLDRVITYSADELVDYSPVTEQNVDGGMSIRELAEATVRTSDNSAANLLLDELGGP +AGFADALTRVGDRTTQPERRETELNTAVPGETRDTSTPRALAETLRGFALDGLLDDTQAA +TLIDWMSGNATGDPLIRAGAPEGWAVADKSGAGGYGTRNDLGIVWPPDGDPIVIAVLTTR +DAADAEYDNALVADVAAVVLE-- +>[subseq from] Beta-lactamase n=1 Tax=Saccharothrix variisporea TaxID=543527 RepID=A0A495WZ95_9PSEU +-----PALTALEQKYGARLGVYALATGSGTTI-AHRADERFAFCSTFKGLAAAAVLHRNP +--LSHLDAVVTYTEQDLMKSSSITRQHVATGMTIRDLCDAAVRYSDGTAGNLLLRDLGGP +AELTAFTRTLGDQVTRMDRVEPDITEATPGDPRDTTSPRAIGTDYQKLVLGDALEPDKRA +FLTDLMTRNTTGNRRIRAGVPTTWTVADKTGTGDYGTLNDIAITWPPGTAPLVIALMSDK +PTADARYDEALLAEAATYVAE-- +>[subseq from] RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI000DE70C44 +---VLEAVTNAETELGARIGLAVHDLETGKRW-EHKSNERFTLSSTFKTLACANVLQRVD +LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP +KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ +QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE +TDASFEERNAVIAKIGEQIAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia cerradoensis TaxID=85688 RepID=UPI0005851FCA +----LAEFRDLEARLHGRLGVYALDTGTGRAV-EYRPDERFPYCSTFKALAAGALLSTLP +--PAELDRRVTYTRADLLPNSPVTEQHVDQGMTLREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRAIGDSTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPSVAADDRD +VLTGLLRANTTGAALIRAGVPAGWQVGDKTGAGDYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDAEYDNAAIARAATIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Pleomorphomonas diazotrophica TaxID=1166257 RepID=A0A1I4W7A1_9RHIZ +---ADDELAALEKRSGGRLGVAALDKATGARL-VHRADERFAMCSTFKFVAAAAVLAAVD +QGKLRLDKSISYGKADLQDYAPVAKEHVAEGLSLEVLCRAAVEMSDNTAANLILKEIGGP +AGWTAYVRALGDATSRLDRTEPSLNTADEGDERDTTTPEAMMGTLDALMVGNALSETSRK +KLEEWMLTGIVTGPLIRAGVPKTWQVADKSGSGGHGTRNDVGIIYRPEKAPILASIYFTG +SDLDMPGRNKVIADTAAIIAARf +>[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix variisporea TaxID=543527 RepID=UPI000EB4C608 +-----PALTALEQKYGARLGVYALATGSGTTI-AHRADERFAFCSTFKGLAAAAVLHRNP +--LSHLDAVVTYTEQDLMKSSSITRQHVATGMTIRDLCDAAVRYSDGTAGNLLLRDLGGP +AELTAFTRTLGDQVTRMDRVEPDITEATPGDPRDTTSPRAIGTDYQKLVLGDALEPDKRA +FLTDLMTRNTTGNRRIRAGVPTTWTVADKTGTGDYGTLNDIAITWPPGTAPLVIALMSDK +PTADARYDEALLAEAATYVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI0007ABBF20 +---SDREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR +TEKDAEYHDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF574A2 +---SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALVSSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=C8CE56_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGGNIKAERIVVIYLRD +TPASMAERNQ------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. WAC01526 TaxID=2588709 RepID=UPI0011E06015 +--RAAKALAQVERRYHSRLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAAVLLKRST +--DDELNRVIRYRASDLEDYAPITKRHVGEGMTLRDLIKAAVQYSDNTAANLLLDRLGGP +AGLQKALRGMGDRTTRTDRTEPALNEAKPGDPRDTSTPRALGTDLRRFVLGDVLPEGRRQ +LLTQVLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPAGGSPIVVAVLSDR +GSKDAASDDALIKDATKT----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TSRI0107 TaxID=1703942 RepID=A0A1Q5L8F0_9ACTN +---VTARLRDLERRYDAKLGVYAHNLGTGKTV-RHHADDLFPICSVFKTLAAAAVLRDLD +HDGEVLARRIHYTEADLVEGSDETRKHLAEGMTIAELCDVTIRYSDNAAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYARLVLGDALPRHDRA +LLTRWLLNNTTSDDRLRAGVPSTWTVADKTGGGSYGTNNNVGIAWTPDGTPVVLAVLSRK +SDPDAVRVNALIADTAKVLT--- +>[subseq from] Beta-lactamase n=1 Tax=Diaphorobacter nitroreducens TaxID=164759 RepID=A0A3N1YRQ8_9BURK +-qQLQAALGRMEQRVGGRLGVAVLDTGSDALA-TYRGDERFALCSTFKLLLAGQVLQRAD +QGLERLDARVRYGRQDLVEYSPRTEPHAGGAMTVAELCEATMVLSDNSAANLLLRRQGGP +AGLTAWLRTLGDAHTRLDRIEPALNDVPAGELRDTTTPRAMVHTVQKLVLGDALSGEARA +RLQGWLLGNLTGDKRLRAGMPAGWRIGEKTGTAN-GTSNDVGVVWPEGGAPAVVACYLTQ +CPAAPAQRDAAIAEVGSLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora zamorensis TaxID=709883 RepID=A0A1C5HTV5_9ACTN +--AAEQEFQRLEKTFQARLGIYAVDTGTGRTV-EHRPDERFAYASTWKALAAAEVLDGTT +--DAELDRVVRYSAQDLVSHAPITEKHVAEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +QGFEKKLRGIGDTVTDPARYETALNEATPGDRRDTSTARALAGDLRAYTVGDALTPADRD +VLRGWLKGNTTGAGLVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVVAVLSSR +DKLDATPDDALIAQATTVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF22259 +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYIGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIADATKIALN-- +>[subseq from] Beta-lactamase n=1 Tax=Franconibacter pulveris TaxID=435910 RepID=A0A0J8VSC3_9ENTR +--QLTAAAQQEEKTLNARIGVAVLDTATGKTA-SYRGDERFPLNSTHKALLCGALLKQAD +EKKVSLTEAVRFDQSRLVEYSPVTEKHTAPQMNWLQLCSAAVSYSDNTAANLISQKVGGP +QGVNAFLRANGDKTTRLDRVEPALNEARPGDERDTTTPQAISRTLQTLLLGDALSEASRK +QLTRWMIDDKVADALLRQSLPKGWTIADKTGAGGYGSRSIISMVWPEKGAPLVVAIYITQ +TDASLSQSNAAIARLGHVIFQQ- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Xanthomonas TaxID=2643310 RepID=UPI001370D40C +--TLKQRLAEIERRSGGRLGVSLLD-GSGAVLgGQRQDERFPLCSTFKFLLAGAVLQRVD +RGELTLERRLPVRKADLLGNSPVSERHVGGTLSAAELCRAAMIYSDNAAANLLLPLVGDP +PGVTRFLRALGDTQTQLDRNEPGMNDFVAGDPRDTTTPAAMAATMRTLLLGEALQPVSRQ +RLIGWMRDNRTGKDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG +AKVDSAARDAALKAVAQAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI00051DEC39 +--MLRAQWADIERGTGGRLGISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLRRVD +QGKLTLAQPVKIRASDMLEHAPVTKRHVGGTLSVGELCRATMIHSDNPAANLLFPLVGDP +AGLTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG +AKVDAAARDAALKAVAVAVREW- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium frigidicarnis TaxID=84698 RepID=A0A1I0V3J8_9CLOT +--QYNSSFSQLESDYGVKLGVYAFDTETNKEV-VYRADDRFAYCSTFKALAAGAVLKQAS +--LEQLKQVVKYNKEDVLSYAPITKDNVDKGMTIEEICNAALRFSDNTAANLLFDHVGGP +NGFKSALNQLGDNVTQPTRIEPDLNEAIPEDIRDTSTPRQLATDLQAYTTGDILTDDKKK +ILIDWMTGNATGNTLIRAGAPEGWVVADKSGTGSYGTRNDIAIVMPPNKKPIIIAILSTH +DTKEAKHDDKLIAQASKIVFDSf +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI00141A9972 +--MLRAQWADIERGTGGRLGISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLRRVD +QGKLTLAQPVKIRASDMLEHAPVTKRHVGGTLSVGELCRATMIHSDNPAANLLFPLVGDP +AGLTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG +AKVDAAARDAALKAVAVAVREW- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. RP1137 TaxID=1380110 RepID=UPI00042964BF +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLEQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTARALATSLQTYVLGQALPENKRA +LLTDWMKRNTTGNALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 04182 TaxID=2203198 RepID=A0A429FN01_9PSEU +--QFHDRLLELEKKFDARLGVYAIDTGGGATI-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVEYSRDDLMKHAPVTGQHVATGMTIRQLCDAAIRFSDGTVGNLLLRDLGGP +AELTAFTRSLGDTVTRMDRIEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTADKRD +FLRDLFERNTTGAQRIRAGLPSGWTVADKTGTGDYGTLNDIAVVWPPDKAPLVVAIMSSK +AAKDAPYDQALLAEAAKYVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio neptunius TaxID=170651 RepID=A0A0F4P6E5_9VIBR +-dTLTQQVAQLETQSGGRLGVAVLDTQNNHQW-QYRGDERFPMMSTFKALMCASALDLAD +QNKLSLNDTTTIKESDLVTWSPVTEKLIGQDMTIQQACEATMLMSDNTAANIVLHQIGGP +QQVTQFVRTLDDKVTRLDRFEPELNQATPGDKRDTTSPHAMVTSLNTILLQDGLSEKNQQ +TLLTWMKNNKISDSLIRSILPQGWSIADRTGAGEQGSRAINALVWNEQHKPIIISLYLTH +TELDIAQRNQTLNQVAKLVLEHf +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. SEMIA4064 TaxID=2127048 RepID=A0A2T3GT50_9RHIZ +--DADKQLADLEKKTGGRLGVSVLDTETNISL-GYREAERFALCSTYKALAVGFVLARVD +QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCGAAIMLSDNTAGNLLLDSFGGP +AALTAWLRTTGDTETRLDRKEPDVNQAIKDDPRDTTTPDSMLDTIGLLTLGNTLSETSRD +QLSNWLVNNTTGNARLRAGLPKEWKVGDKTGTGQNGSYADVAVIWPTDRGPILVTTYVGE +ATAPAKDIEAVFAEVGKIIA--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis alba DSM 44262 TaxID=1125972 RepID=A0A229RD96_9PSEU +--QFHDRLLALEKKFDARLGVYALDTAGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRISYSRDDLMKHAPVTGQHVATGMTIRQLCDAAIRFSDGTAGNLLLRDLGGP +AELTAFTRGLGDTVTRMDRIEPLITEATPGDPRDTTTPRAFGTDYQRILLGDTLETDKRD +FLRDLLQRNATGAERIRAGLPPGWTIADKTGTGDYGTLNDIAVVWPPGKPPIVMAVMSSK +AAKDAPYDQALLAETAKYVVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. DJ TaxID=2067551 RepID=A0A2N5XG17_9ACTN +-----RELEDLERKFDARLGVYAVDTGTGREV-AHNDGERFPYASTFKALAAGAVLDKHS +--LKGMDKVVTYSRDDLVAHSPVTEKHVGTGMTLDELCEAAVRFSDNTAANLLLDELGGP +RGLDAVLEEIGDDVTRAERREPELSRWVPGETRDTTTPRALAGDLRAFVLGDVLGKDERA +RLTKWLRTNVTGDDLIRAGVPGDWVVGDKTGTGSYGARNDIAVVWRPGAAPVVMAIMSNR +KERGAEPDDRLIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1W5MZS1_9BACT +-qDLQATVSAWEERLDARIGVVLRDASSDWEI-AMRADERFPMSSTFKSLLCGAVLARVD +AGQENLDRRITYTADDLVTYSPVTEEHLDDGLTVSELCEATVTLSDNTAGNLLLEAVGGP +EGLTTFLRGIGDETTRLDRWETALNEGAVGDPRDTSTPSAILNTLETLLLGDVLTPASAA +QLRQWMIDDAVADTLIRAHLPDGWVIGDKTGAGGNGSRAIIAFIQPEAGVHYFAAIYITE +SDADFALRNQVVSEIGQAMI--- +>[subseq from] Beta-lactamase n=1 Tax=Kribbella albertanoniae TaxID=1266829 RepID=A0A4R4PJB6_9ACTN +-----ARFQELEKQYAARLGVFAVDTGSRRTV-SYRADERFAFASTVKSLACGVLLRQAK +----DLDKLIRYTAADLVTYSPITEKHVDTGLTLYQLCDAAIRYSDNTAANLILVELGGP +AGLQRALRKLGDGITNVNRNEPTLNEATPGDRRDTTTPCQLATSLQKFTLGHALPPAKRA +ILNNWLLTNTTGDKTIRAGVPKDWKVGDKTGTAGYGGRNDVAVIWPPNRAPIMLAIMSTK +GVKDAPTDDALIAAAAAAAIN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B5J6R8_9BACI +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKYDAKYDDKLIANATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces thermocarboxydus TaxID=59299 RepID=UPI0010C0DF18 +------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDHRP +--GARLDERIPYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAGNLLLRDIGGP +RGLTAYARRLGDRVTRLDHTEPELNGNPPGDPRDTTTPRAIAADYRALVLGDALPAAGRT +MLTDWLVRNTTGDRRIRAAAPRGWRVGDKTGGGEYGRGNDVAVLWPGGRPPLVLSVLTER +PGRAATPSDELVAEAARRVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia tenerifensis TaxID=228006 RepID=UPI000594468B +-----RSFTDLETKAGARLGVYAIDTGTGRSV-AYREGERFPIASTFKGIACGALLREHP +IASGFFDQVIHYSRTDLVDNSPETEKHVDTGMTVAELCKAAITLSDNTAGNQILKLLGGP +EGFTAFVRSLGDTSTRLDRWETELNTAVPGDERDTTVPAALAADYRALIVGDVLSDPERA +QLKTWLLANTTGGKRIRAGLPTDWAVGDKTGTPAYGAALDVAVAWPPNHAPIVIAVLSSK +SEQRAEPDNALIADATRTAIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF1B1DD +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKYDAKYDDKLIANATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Kosakonia cowanii TaxID=208223 RepID=UPI00111F48B4 +-qTLQKKIEMLENKSGGKLGLTVVDTSDGTMY-SWRGDEKFPLCSTSKVMVVAAILKKSE +SNTNLLAKKITINKSDMVNYNPITSKYIDSSMTITELSKAALQYSDNAAMNKLLSYLGGP +RYATQFARTIGDKAYRLDRNEPGLNTAIPGDSRDTTTPSAMAETLNKLILGNALKKEQKA +KLTEWMKGNTTGLNSIKAGLPAEWIVADKTGSGDYGTTNDVAVIWPKNHAPVILTTYFTQ +PEKDASARKDVLASAAKLIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNT371 TaxID=1136433 RepID=UPI00047FAD54 +-----RELAALEREYDARLGVYAVDTGSGREV-AYRAGERFPYASTFKALAAGVVLRTHS +--ERELDRVVTYSADDLIAHSPVTGEHVATGMTLRDLCEAAVRYSDNAAANLVLAELGGP +AGMDAELEALGDDVTRMVRDEPELSRWKPDDTRDTSTPRALAEDLRALVLDDALGKRDRA +RLTEWLRTNTTGDTLIRAGVPGNWRVGDKTGTGSYGARNDIAVLWPPDRAPIVLAVMTNR +TQRDAEPDDALLADAASAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. L2 TaxID=2162665 RepID=UPI001010BD74 +----DDALLDLEQNYGARLGVYARNVRTGDTV-SYRAGERFAMCSTFKTFASAAVLRDHA +-DCAPLDRVIHYPQRDILDNSPKTAEHVDAGMAVGDLCAAAIQYSDNAAGNLLLRQIGGP +AGLTRFMRSIGDEVTRLDRWETDLNSAIPGDLRDTTTPEAVGRSLEEVALGRVLAPADRE +QLLTWLKGNTTSAKRFRKGLPQDWTVADKTGTGDYASANDIGIAWTTRKTPLVLAVLSAK +PAKKAPVDDDLIAEAARLAA--- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia sp. JS23 TaxID=1770053 RepID=A0A1H2PMW4_9BURK +--SVAAEFARIEAATGGRLGVAVEDTASGRRL-AYRGGERFPMCSTAKLLVCGAVLQRVD +AGRDTLDRLVSFAPSALVTYSPATQPHAGTDMTLEALCVAAMTLSDNTAANLLIASVGGP +RGVTALARSLGDTVTRLDRNETTLNEAKPGDPRDTTSPIAMSSNVKALLYGTALSAPSRQ +RLLGWMNGNITGGAKLRAGVPGNWQVADKTGSGGHGTSNDVAVLIPPGTAPWPIAVYLTG +AVIDESARSAAIAAVARAVVRAw +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. UNC305MFCol5.2 TaxID=1449076 RepID=UPI0004A70043 +--EFRKAVLAVEQASGGRLGLAVTDTGSGERF-GWRADDRFPMCSTFKFALAALILKQVE +RKRETLARQIPVAQADIVSNSPFSEKRVGGSASVAELCHATITVSDNSAANLLLRTIGGP +AGFTKWLRSAGDPATRLDRWETEMSEAKPGDVRDTTTPVAMAGLARHLLLGDALTPVSRT +QLTDWMKDTRTSRNSLRAGLPADWAVADKTGAGGYGTDNLVAVLWPPRRPPLVVASYITG +STLEFEKRRPLHAGIGRAIVA-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=A0A1N6KQG6_9BURK +--SVEGQLAKLEQTAGGRLGVSALNTANGTWI-GHRADERFPFCSTFKVILSGAILARST +QAAGFMQQRIHYAQSDVVHYSAVTAEHIGDGMTVAELCAAAIQHSDNTAANLLIKLLGGT +DAVTAYARLIGNDVFRLDRLETSLNDAVPGDPRDTATPASMVRSLHTLTLGDTLPIAQRT +QLLDWLRGNQMGSKRIGAALPAGWTMGDKTGTGDYGTANDLAVIWPPSRPPLILGIYHTQ +PGQDAKARDDVVAAAARIVV--- +>[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. AP09 TaxID=2135476 RepID=A0A395KTF2_9RHIZ +-----PKIRRIEAKSGGRLGVACRIAGTTVQF-GYRENELFPMCSTFKALAAALILHRVD +DGIEQLDRSIEVPHDAIIANSPTTKKFAGGAMTVAQLCEAAVTVSDNGAANLLLSSFGGP +PQLTAYLRSIGDTVTRLDRIEPELNESIPGDARDTTSPLAMIDDYERLTLGDSLSHKSRA +QLVDWLVANKTGDDRIRAGLPKGWKCGDKTGTGAHGSTNDAAVIWPASGNPILMSVYLTG +TKQSLAKRNAVIASVSRALVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-118 TaxID=1463881 RepID=UPI0004C80E25 +-----RELRELERRFGARLGVHAVDTGTGREV-AYNDGLRFPYASTFKALAAGAVLRKYT +--VGGMGERVTYSRDELVEPSPVTEKHVATGMTLDALCEAAVRFSDNTAANLLLDRLDGP +KGLDAVLEGIGDDVTRMERREPELSRWVPGDTRDTTTPRALARDLRAFVLGDVLGPAERA +RLTEWLKTNVTGDELIRAGVPKGWVVGDKTGTGSYGARNDIAVVWPPDGAPIVMAIMSNR +GEKDAEHDNRLIAQAASVVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia tenerifensis TaxID=228006 RepID=A0A318KCJ4_9NOCA +-----RSFTDLETKAGARLGVYAIDTGTGRSV-AYREGERFPIASTFKGIACGALLREHP +IASGFFDQVIHYSRTDLVDNSPETEKHVDTGMTVAELCKAAITLSDNTAGNQILKLLGGP +EGFTAFVRSLGDTSTRLDRWETELNTAVPGDERDTTVPAALAADYRALIVGDVLSDPERA +QLKTWLLANTTGGKRIRAGLPTDWAVGDKTGTPAYGAALDVAVAWPPNHAPIVIAVLSSK +SEQRAEPDNALIADATRTAIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. SHU 308 TaxID=1591201 RepID=UPI00039A65E3 +--TLQLRLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD +RGELALERRVPVRKADLLANAPVSERHVGGTLSVVELCRAAMIYSDNTAANLLLPLVGDP +PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPRDTTTPAAMAATMRALLLGEVLQPVSRQ +RLIAWMRDNRTGNDCLRAGLPAGWQIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG +ATVDSAARDATLKAVAQAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Psychrobacter sp. PAMC 21119 TaxID=1112209 RepID=UPI000288271E +--SLVDAVKSAENELGARIGLAVHDLETEQRW-EYRSDERFPLSSTFKTLACANVLHNVD +IGQEKIDRVVRFSKSNLVTYSPVTEKHVGKKMSLGELCQATLSTSDNSAANFILQAIGGP +KSLTQFLRASGDNTTRLDRWETELNEAIPKDKRDTTTPIAMITTLEKFVVGDTLSTESRQ +QLQSWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPGRKPVIAALYITE +TDASFEDRDAMIAKIGTEIAK-- +>[subseq from] Beta-lactamase n=1 Tax=Actinopolyspora righensis TaxID=995060 RepID=A0A1I7C3I4_9ACTN +-----EDFERLEREFDVSLGVYAVDTATGREL-SYRADERFAYASTHKALTAAAVLRRTS +--LEGLDKRITYDRSDLVAYSPVTKKHVDSGMTLRSVLDAAVRYSDNTAANLMFDELGGP +EGLSAVLREIGDATTHVDRIEPELNATEPGDIRDTSTPRALATSLRAFTVGNALPKDERA +VLNRMLRNVTTGDELIRAGAPDGWRVGDKSGAADYGTRNDIAVLWPPKRAPIVLAVLSDR +DAADAEYDNALIARAAEVALRSf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus horneckiae TaxID=549687 RepID=A0A2N0ZLR3_9BACI +----AEKFGKLEEEFDARLGVFALDTGTNQTV-EYRSDDRFAYASTHKALAVGALLQQKS +--IEELNERITYNHDDLVEYSPITEKNIDKGMTLKELSDASIRYSDNTAANLILKELGGP +DGFKKSLREIGDAVTNPERFEPELNDVKPGEIQDTSTPKAMAESLKAYVIEDTLPEEKRA +ILTDWLKRNTTGDALIRAGVPKGWEVGDKTGAASYGTRNDIAVIWPPKGEPIVLAILSSR +DKKDAETDDKLIAEATKEVIN-- +>[subseq from] Putative beta-lactamase class a protein n=1 Tax=Xanthomonas albilineans (strain GPE PC73 / CFBP 7063) TaxID=380358 RepID=D2UF46_XANAP +--ALQQRLAEIERRSGGRLGIYLLDSGTGQRI-GRREQERFPLCSTFKFVLVVAVLQRVD +RGEIGLDQQVRVRAADVVSYAPVTKPHVGGTLSVDALCRAAMIFSDGGAANLLLRLVGDP +PGLTRFLRAHGDTQTRSDRNEPSMNAFALDDPRDTTTPAAMASTMRTLLLGDVLQPASRQ +RLIDWMIDNRTGDDCLRAGLPAGWRIGDKTGNNGTDSRNDIAIVWPPGRAPLLLTAYLNM +ATVDSDARDAALKAVAQAVVAWw +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0009E53A72 +--ATIKKFEQLEKEYDAKLGVYAIDTGTKETV-EFHENERFAFTSTHKALAVGALLQQKS +--IEELNQRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP +AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DEKEADYNDELIAEATEEVIK-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Psychrobacter TaxID=196806 RepID=A0A2I0GIF9_9GAMM +-----DSVKNAENKLGARIGMAVHDLETEQRW-EYRADERFPLSSTFKTLACANVLHNVD +LGQEKIDRVIRFSKRNLVTYSPVTEKQVGKKMSLGELCHATLSTSDNSAANFILQAIGGP +KSLTHFLRSIGDNTTRLDRWETELNEATPKDKRDTTTPMAMITTLEKLVVGETLSTESRQ +QLQSWLKANEVGDALFRKGVPSDWIIADRTGAGGYGSRAITAVMWPPGRKPIIAALYITD +TDASFEDRNAVIAKIGIEI---- +>[subseq from] class A beta-lactamase n=1 Tax=Actinokineospora inagensis TaxID=103730 RepID=UPI0004171BD2 +----GTDLAELEAAHGARLGVWGRNTRTGRTV-EYRAGERFPMCSTFKTVAAGAVLRDRF +---SPLDRVIHYPPSDLVPNSPITGEHVDTGLSIGDICAAAIQYSDNTAGNLMLRQIGGP +PGLTGFFRAIGDQTSRLDRWETELNTAIPGDPRDTTTPAALGRDYERLTLGDALSHPDRE +RLVTWLKGNTTSAARFHKGLPATWTIADKTGTGDYATAHDIGVVWTGHGTPLVLAVLTTK +STKDAPADDDLIAEAARLAAN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. OK228 TaxID=1882786 RepID=A0A2C8X962_9ACTN +--------RELEARHGARIGAFAYNLRTKATV-RHRAAERFPLCSVFKTLAAAAVLRDLD +RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PAQDAAPDSPLVAAAASVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Methylophaga sp. TaxID=2024840 RepID=A0A2E2D8T8_9GAMM +---WQTTFAQLEKEYGGRLGIAAYDLQHQFQL-HYRANERFALCSTFKVLLVANVLHRID +QHQESLSRPIHYDRADILDYAPVTKTHLDEGMSVAALSQATLQLSDNTAANLLLKTIGGP +EALTDYLRSIGDNTTRLDRIEPALNSNLAGDLRDTTTPAAMLATLNTLLLGDHLSDVSKQ +RLIQWLIGNQTGDDKIRAGVPSTWLVGDKTGSGPNGAFNDVAIIWPEKGKPYLLVIYYSE +STLTKQKKAELLAKISESVS--- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A2G7BXD4_9ACTN +--------RELEARHGARIGAFAYNLRTKATV-RHRAAERFPLCSVFKTLAAAAVLRDLD +RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLTTK +PARDAAADSPLVAATATVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces mirabilis TaxID=68239 RepID=UPI000944746E +hrDTRAGLRELEARHGARIGAFAYNLRTKATV-CHRAAERFPLCSVFKTLAAAAVLRDLD +RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGAYGTSNDVGIAWTPDGAPVALAVLSTK +PAQNAAPDSPLVAAAASVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. C06 TaxID=1945854 RepID=A0A1V3P852_9GAMM +--DVEARLAALERRHGGRLGVAILDTGTGRRH-GHRADERFLMCSTHKLLTVGAVLARVD +RGVERLDRRVVFGRDVVLSWAPVTSKHVGAPMSVAELCEAAITVSDNTADNLLLRSLGGP +PAVTAFARKLGDPLTRLDRYEPELNVGAPGDLRDTTTPDAMLGNLRALLLGDVLSVASHE +RLAAWMRATSTGLDKLRAGMPSGWQAGDKTGSGAHDETNDVAIFWPPQRKPLLVTAYLAG +STAGAAGRSAVLAEVGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces katsurahamanus TaxID=2577098 RepID=UPI001295D810 +-----SQLAALERKHGARLGVYALATGTGATV-AYRADERFAFCSTFKTLAVAAVLHRNP +--LSRLSERVTFTQADVNSISPITRDHIGTGMTIRQLCDAAIRHSDGTAGNLLMRDIGGP +ARLTAYLRGLGDTVSRMDHYEPELNRVPPRDPRDTTTPRAIGGDYRRLVLDDALSADKRA +LLKDWLERNTTGDKRIRAGVPRAWTVADKTGTSRYGRANDIAVVWPPGQAPLVVAIMSDR +PGQDTPPKETLIAEATARIV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. B27 TaxID=2485015 RepID=UPI000FD6CF13 +---TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS +--LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATVRYSDNAAANLLFRELGGP +RGLQDALRGIGDDVTRCDRYEIALSDATPGDPRDTSTPRALATDLRAYALGPALPAEKRA +LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR +DVKGAESDDALIAGASKVALEAf +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WRZ8_9BACT +-----RKLAELERHAGGRLGVAAVDTATGQRL-EHRGNERFAMCSTFKFLLAAALLQRVD +KGVEHLNRRIEYGEADLLEYAPVSKQNVKQGMALAEMCSAAVEWSDNTAANLLLQALGGP +DRLTAFIRTLGDEVTRLDNNEPKLNVVLPGEVHDTTSPLSMVRLLSTLLFGQVLSPDSRT +RLQGWMLDAKVGQHRLPAGLPPFWRIAHKTGTGSD-QTNDVGVLWPPDRAPIVVAALYAR +GDIPQDRREAVLADVGRIVSSVf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Aeromonas sp. TaxID=647 RepID=A0A5B9T783_9GAMM +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIATLGPDGKPSRIGVIYMTG +SQA-------------------- +>[subseq from] Class A beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A429A4W2_9ACTN +-----RSLAGLEREHGARLGVYAVDTGTGATV-VHRADERFAICSVFKTLAAAAVMDRGP +--LSRLDERVRYTRDDLVTYSPVTEKHTGTGMTLRELCDAAVRESDNTAANLLLRDLDGP +AALNAYLRGLGDSVSRLDQYEPHLGGNPPKDPRDTTTARAVAADYRALVVGDALPAAKRT +LLTEWLVGSTTGGERIRAGAPRGWKVGDKTGTGDYGRANDVAVLWPERGAPLVLAVLTDR +PDRDAEPSNPLVAEATRRVLE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000C9AD226 +---SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA +LLTDWMNRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=S5TLV0_9BACT +--TYQAKFTQLESNANGRLGIMAINTANNQQI-EYRSNELFPFCSTGKVMVVGAILKASE +SNTQLMQRQLHYSKQDTESYAPITKQHIADGMNVSALSQAAIAYSDNGAMNQLLQLLGGP +QAITSYARSLGDNKFNLVRTEPQLNTAIPNDERDTTTPAAMALSLQKLGLGTALDKKQQT +RLQEWLKANTTGDKRIRAGVPKGWTVGDKTGTGSYGTTNDIAVIWPPHAKPIVLVVYFTQ +NKKDAKPNDQVIAQATKIVIDEf +>[subseq from] Beta-lactamase n=1 Tax=Enterobacterales bacterium CwR94 TaxID=2025587 RepID=A0A2I0G0H9_9GAMM +---TVDKVKTLENKISGRIGYAEIDLASGKLIdGYRTDERFPMMSTFKTLVCGAVLERVD +QGKEHLSRRINYQQSDLITYSPVTEKNIESGMTIEELCRATVSVSDNTAANLLLNIIQGP +QALTHFLRGINDPVTRLDRYEPDLNDAVPGDERDTTSPLAMANTLRKLLKGDTLTAESRD +LLTQWMIGDEVAGALIRSVLPSGWFIADKTGAGRHGSRGIIAMLGPDNQPSRIVVIYITN +SKTDIDEQNRIIAEIGASIIANw +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5TP90_9BACT +--DAAARVAAIEARIGGRIGVAALDTSNGKRL-DHRAEERFPMCSTFKFLAAAAVLKRVD +EKQEKLDRFVSYGAKDILEHAPVTKERLKDAMTLGALCEAAIEQSDNTAANLLLDAIGGP +ASLTHFARNLGDQITRLDRKEPDLNSAIAGDERDTTTPGAMCLDMQRLLVASVLSESSRR +QLEDSLLRNKMGGLMIRAGVPKTWSVGDKSGRCANGATNDIAIIRPPDRAPILLAIYSVG +STAPANNREMAIAEVAKIVAELf +>[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. J56 TaxID=935850 RepID=A0A1X7IWZ2_9RHOB +---VTAAVRQAETELKARVGYAQLDLRSGNVT-GYREDERFPMLSTFKVLVCGAVLARVD +AGKEDLARHINYPATQLVDYSPVTEKHVDDGMTLSALCEAAITMSDNTAGNLLLEAVGGP +EGLTSFLKATGDNIGRLDRWETELNSAIPDDPRDTTTPNAMAKTLHRLLFGDVLSDQSRD +QLLNWMQNDRVADALLRAALPQGWYIADKSGAGDRGARAIVAALGPNGAPERIMVIYMTE +TDAALDERNAQIAKIGKALIANw +>[subseq from] class A beta-lactamase n=1 Tax=Diaphorobacter polyhydroxybutyrativorans TaxID=1546149 RepID=UPI0011E4D06C +-qQLRAALGRVEQRVGGRLGVAVLDTGSDALA-TYRGDERFALCSTFKLLLAGQVLQRAD +QGLERLDARVRYGREDLVEYSPRTEPHAGGAMTVAELCEATMVLSDNSAANLLLRRQGGP +AGLTAWLRTLGDAHTRLDRIEPALNDVPAGELRDTTTPRAMVHTVQKLVLGDALSGEARA +RLQGWLLGNLTGDKRLRAGMPAGWRIGEKTGTAN-GTSNDVGVVWPEGGAPAVVACYLTQ +CPAAPAQRDAAIAEVGSLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. CMAA 1363 TaxID=1843182 RepID=UPI000AC1E58A +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQKYVLGQALPEDKRT +LLTDLMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAKYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase L2 n=1 Tax=Candidatus Sulfopaludibacter sp. SbA3 TaxID=2043164 RepID=A0A2N9MV63_9BACT +---LPAALAQLEQTNGGRLGVAVVDTATGERS-GHRANERFPMCSTFKFLLASAVLQRVD +RHLETLDRAITIPPKPLLGNSPLTEPHAGGTMTVAALCHAALTRSDNTAANLLLESIGGP +ASITAFARSIGDTVTRLDRMETSLNESLAGDPRDTTSPRAIAGDLHRVLLGNVLKPASRD +QLTVWMEANLTGLERLRAKLPKSWHAADKTGSNGEHTSNDIAVVWPAGKPPIIIAAYITQ +CMGPESKRSALLAEIGRLV---- +>[subseq from] Class A carbapenemase SME-5 n=1 Tax=Serratia marcescens TaxID=615 RepID=X4Z2B6_SERMA +--AAAKQIKKLEEDFDGRIGVFAIDTGSGNTF-GYRSDERFPLCSSFKGFLAAAVLERVQ +QKKLDINQKVKYESRDLEYHSPITPKYKGSGMTLGDMASAALQYSDNGATNIIMERLGGP +EGMTKFMRSIGDNEFRLDRWELELNTAIPGDKRDTSTPKAVANSLNKLALGNVLNAKVKA +IYQNWLKGNTTGDARIRASVPADWVVGDKTGSCGYGTANDYAVIWPKNRAPLIVSIYTTR +KSKDDKHSDKTIAEASRIAIQ-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces parvus TaxID=66428 RepID=A0A5M8GR77_9ACTN +------DFKKLEREFDARLGVYAIDTGTGREV-THNDRDRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVTYAREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +GGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGRALGAPERA +QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR +GTKDAEPDDRLIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces malaysiensis TaxID=92644 RepID=A0A291SIX6_STRMQ +--AFTGEFKKLERAHDARLGVYAIDTGTGHEV-AYRDGERFAYASTFKALAAGAVLRKYS +--LSGLDRVIKYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDELGGP +GGLDAILEKMGDDVIQMEHYEPELSRWVPGATADTSTPRAMAKDLRAFVLGDVLGKGERA +QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGSGSYGARNDIAVVWPPDAAPIVMSIMSYR +GDKDADYDEKLIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces malaysiensis TaxID=92644 RepID=UPI00142EACAE +--AFTGEFKKLERAHDARLGVYAIDTGTGHEV-AYRDGERFAYASTFKALAAGAVLRKYS +--LSGLDRVIKYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDELGGP +GGLDAILEKMGDDVIQMEHYEPELSRWVPGATADTSTPRAMAKDLRAFVLGDVLGKGERA +QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGSGSYGARNDIAVVWPPDAAPIVMSIMSYR +GDKDADYDEKLIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. CH30_1T TaxID=2604836 RepID=A0A5A9E198_9BACI +------GFKELEKEYDARLGVYALDTGSNQSV-SYRADERFIYASTHKALAVGALLKKKS +--IDDLDKKINFTEKDLVNYNPITEKHVDTGMTLKELSDASIRYSDNTAGNLIFEAIGGP +KGLMEVLRGIGDDVTEPDRIEPDLNNVEPGETRDTSTPKALAESLQAFTLGNALPEEKQN +LLNDWLKRNTTGDALIRAGVPEGWIVGDKTGAGSYGTRNDIAVIWPPDGYPIILAVLSSR +EKADAEYDDELIAKATEIAIK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC05374 TaxID=2487420 RepID=A0A3R9W946_9ACTN +------RLRALERRHGARLGAVARNTVTGATV-LYRADERFPMCSTFKTLAAAAVLRDLD +RHGEVLARRIRYTAADIVVNSPRCEENLATGMTVAELCDATIRFSDNTAANLLLRELGGP +TAVTRFCRSLGDGTTRLDRWEPELNTCEPWRVEDTTTPAAIAGTYERLVLGDALERGDRE +RLTGWLLGNTTSTHRFRAGLPEDWRLADKTGGGSYGTNNDVGVAWTPEGAPVVLAVLTTK +PVQDAPSDDLLVARAASVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NBRC 110465 TaxID=1897621 RepID=UPI0009325674 +------DFEELERTFDARLGVYAVDTGTGREV-THNDRARFAYNSTFKALQAAVVLQTYS +--LDGLDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNAAANLLFDHVGGP +EGLDASLEKLGDDVTRMDREEPELSRWVPGEQRDTSTPRALAGDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIRAGVPEGWGVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPEDRLIAEAASVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hirsutus TaxID=35620 RepID=UPI0006E28A98 +------DFRELERTYGARLGVYAVDTGNGREV-AYNDNERFAYASTFKAFAAAAVLREYS +--LSGMDEVITYSGDDLSAHSPVTEKHVDTGMTLRELCDAAVRHSDNTAANLLLDALGGP +KGLASALAEVGDTATRVERREPELNQWAPGETRDTTTPRAWAGDLRAFVLKDALGRKERA +QLTKWLRTNTTGDELIRAGVPQGWVVGDKTGGGGYGVRNDIAVVWPPDAAPIVMAIMSNR +GTEDAEYDNKLIEEAASVVTR-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea vagans TaxID=470934 RepID=UPI00111D4B09 +-qSLNNQFEKLERQSGGRLGLAVIDTSDSAQY-SWRGNERFPLCSTSKVMAVAAILKKSE +NADTLLNKKIHISQHDMVNYNPVTMKHIGSAMSLAELSAAALQYSDNAAMNKLLAYLGGP +QHATQFARTLGDTTFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNKLILGSALKDDQKA +TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPIVLTTYFTQ +HDKSAAARKDVLASAARVIAD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC07061 TaxID=2487410 RepID=A0A429RCH6_9ACTN +--RVARALAALEREHGARLGVYALETDTGRTV-THRADELFPMCSVFKTLAAAAVLRDLD +HDGSVLARRVHYTQADIDRYSEWTKRHLANGLTIAELCEVSITYSDNTAANLLLRELGGP +DAVTRFARSVGDPVTRLDRWEPELNSAEPDRVTDVTTPRAIARTYARLVLGDALGRADRG +LLTGWLCANTTSGARFREGLPAEWRLGDKTGGGSYGTNNDVGIVWRPHGAPLVLAVLTTK +PAQDAKADDALVSGAARVLAKAf +>[subseq from] Beta-lactamase n=1 Tax=Porticoccaceae bacterium TaxID=2026782 RepID=A0A2E0LIT0_9GAMM +--DIETRLAEIEASVKGHLGVGILDTKTGAFY-GRRVNERFPLCSTFKFLAAAMILERVD +RGVEQLDRRITFTKSDLAPYSAVTKNRTGAKMTLGELCAAAIAFSDNTASNLMLSSLGGP +KALTQFLRSLGDKATRVDRLLPAASKVSPGDPRDGTTPRAMAYTTQRLLFGNVLSKASET +QLIDWLVSSQTGDARLRAGLPKDWRVGDKTGTCS-GATNDVAVIWPPDRPPIIIAAYLND +TNATAAKRDAALADVARVAA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD200 TaxID=1053244 RepID=J8MWY2_BACCE +-eQTHQKFSQLEKEFDAKLGIYALDTSTNQTV-IYNPNERFAYASTHKALAVGVLLQKKS +--IEDLDQRIMYTDKDLVNYNPITEKHIDRGMTLKELADASLRYSDNTAQNLIFKQIGGP +DGFKKALQEIGDTVTNPQRIEPELNDVNPGETPDTSTPKALAASLQTFILGDVLPTEKRN +LLIDWMKRNTTGDKLIRAGVPKGWEVADKTGAASYGTRNDIAVIWPPNKKPIVLAILSNR +DKKEAKYNDQLIAEATKIALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNS335 TaxID=1169160 RepID=UPI0003804EA8 +-----RELAALEREYDARLGVYAVDTGSGREV-AYRAGERFPYASTFKALAAGVVLRTHS +--ARELDEVVTYSADDLIAHSPVTGEHVGTGMTLRDLCEAAVRYSDNAAANLVLGELGGP +AGMDAELEALGDDVTRMVRDEPELSRWHPDDTRDTSTPRALAGDLRALVLDDALDKRDRA +RLTEWLRTNTTGDTLIRAGVPETWRVGDKTGTGSYGARNDIAVLWPPDRAPIVLAIMTNR +TQRDAEPDDALLADAASAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDE118E +----EAQLAALESKHPGRICVSILDLASGKRI-EHRAGERILMCSTFKALAAALVLARVD +KGDEKLDRRIHYKKSDLVDYSPATEPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP +KAVTAFCRSLGDDLTRLDRTEPTLNYDTPDDQRDTTTASAMLENLRRLLFTDILTAASRS +QLAAWLITNKTGDTRLRAGLPKDWLVGDKTGTNGYGNANDIAVLWPSKHAPIIVTAYCEI +PAIAADERNAIIAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Acrocarpospora macrocephala TaxID=150177 RepID=UPI0012D3471A +-----TRFAALEHKHDARLGVYALATGTGATV-TYRADERFAFCSTFKALAAAAVLHQNP +--LSHLNKRVTYTSAEVNSISPITENHIGTGMTIRQLCDAAVRYSDGTASNLLVRDIGGP +AQLTAYLRGLGDTVSRMDNYEPELNSNPPRNPRDTTTPRAIAADYHKLVLDDALTTGKRA +LLKDWLERNTTGDKRIRAGVPQGWTVADKTGTGNYGRANDIAIVWPPDTAPLVMAIMSDR +SGYSTPHKESLIAEAAARIV--- +>[subseq from] Beta-lactamase class A n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A2A3II57_9ACTN +----HQTLRRLEREHQARVGAFAHNLTTGARV-AYRAHTRVPLCSVFKTLAVGAVLRDLD +HNGETLARRIHYTRADLVDNSPVTGAHLATGMTIAGLCAAALQRSDNTAANLLLRELGGP +AAVTAFARSLGDRTTRLDRWETELNSAEPWRRTDTTSPAAIAHTYTRLLVGDALTPADRG +RLTAWMKANETNTDRFRAALPKDWALADKTGTGSYGTGNDVGVAWTPDGTPVVLAVLTGK +PEQAAACDDALIADVTKVLA--- +>[subseq from] Beta-lactamase n=2 Tax=Micromonospora inyonensis TaxID=47866 RepID=A0A1C6R7L2_9ACTN +--------GALEARFGARLGVYAVDAGSGATV-VHRTDERFAYASTFKALAAAALLDATA +--AQELDRVVRYTRADLLPHAPVTGRHVGTGMSLRDLAEAAVRHSDNTAANLILAELGGP +AGFAGHLRALGDRTTKPTRTEPALNEATPGDDRDTSTPRALATDLRAYVLGDALDAEDRA +LLTDWLRRNTTGGGLIRAGVPAGWLVGDKTGTGGYGTRNDIAVLWPPGRAPIVLAVLSSR +DAEDADHDDALIAEATRVTLD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 70 TaxID=1827606 RepID=A0A2G7EX01_9ACTN +-aATGDRLRELEQQHGARLGVFAHNVRTKETV-DHRADELFPVCSLFKTLAAAAVLRDLD +RHGEVLARRIHYTEADLVDGSDRTREHLAEGMTVAELADVAIRYSDNTAGNLLLRELGGP +TAITRFARSIGDPVTRLDRWETELNSAEPWRVTDTTTPRAIGRSYARLVLGDALNRPDRE +LLTHWLLNNTTSGNRLRAGLPKTWTVADKTGAGSYGANNNAGIAWTPEGTPVVLAVQVTK +PERDAAWDHELIAEAAAVLAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Alkanindiges illinoisensis TaxID=197183 RepID=UPI00047D5439 +--QVNVFLAQLEKQAQGRLGLSAINTANQMRI-DYRASERFPLCSTFKLVAVAAILQQSM +HNASLLQQHIDFTLQQVQDYAPITAQHVDRGMTVSELCAACISYSDNAAANLLLQILGGP +AALTRFTRHIGDHIFRLDRWEPALNTALPHDERDTSTPTAMTNTLQRLLLGNVLAPTQRE +LLLYWLKNNTTGNARIRAGVPNGWIVGDKTGTGAYGTSNDIGIVWPTQQAPIILAIYFTC +PDKTAKPNDAIIASASRIVCQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Tu 2975 TaxID=2676871 RepID=UPI001359AC6E +-----RAFARLEREFDARLGVYAVDTGSGRTV-THRPDERFAYCSTHKALTAAAVLEQNS +--LAGLDKVVRYTRDDLVDHSPVTEKHVDSGMTLRAVCDAAVRYSDNTAANLLFDELGGP +KAFQATLAALGDTITHADRLETDLNEATPGDIRDTSTPRALAGDLREYVLGDTLDADRKA +LLIDWLKRNTTGDALVRAGVPGTWEVGDRSGGGDYGTRNDIAVAWPPGGAPVVLAVLSSR +AAQDAEYDDRLVARAAEVVVA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9LAR5_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGEFCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAGTLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD +TPASMAERN-------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 2112.5 TaxID=1907386 RepID=A0A419VI42_9ACTN +----HQTLRRLEREHQARVGAFAHNLTTGARV-AYRAHTRVPLCSVFKTLAVGAVLRDLD +HNGETLARRIHYTRADLVDNSPVTGAHLATGMTIAGLCAAALQRSDNTAANLLLRELGGP +AAVTAFARSLGDRTTRLDRWETELNSAEPWRRTDTTSPAAIAHTYTRLLVGDALTPADRG +RLTAWMKANETNTDRFRAALPKDWALADKTGTGSYGTGNDVGVAWTPDGTPVVLAVLTGK +PEQAAACDDALIADVTKVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis ganjiahuensis TaxID=239984 RepID=UPI000349A920 +---LDSEFTRLEEEFDARLGVYALDTGTERSV-EFQADERFAYCSTFKALAFGAVLDRTS +--LEDLDRVVTYSEDDLVFHSPVTQEHVSTGMTLREIGDAALRHSDNTASNLLFEELGGP +EGLGEALRGIGDDVTSVDRTAPEMAEAVPGDERDTSTPRAMAASLRAFALEDVLPEEKRD +VLVDMMRDNTTGDGLIRAGVPDGWEVGDKTGACGYGTRHDVGVVWPPGEEPIVLAVMSSR +DEEGAGYDDALIAQATATAVD-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1IXX2_9ZZZZ +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +S---------------------- +>[subseq from] Beta-lactamase n=1 Tax=Blastococcus sp. DSM 44268 TaxID=1550231 RepID=A0A1G7LDL5_9ACTN +---VAPALQQLEAEFGARLGVFALDTGTGRTV-EHRADERFAYASTHKALSAALVLDRTT +--DAELDQVVAYDADDLVAHSPVTERHAGTGLPLREVLQAAVSESDNTAANLLLARLGGP +EGFQQALRDLGDDVTQADRFETQLNEATPGDERDTSTPRALATDLRAFLLGDALSEEDRA +LLTGWMQESTTGSALIRAGVPAGWAVADKSGAGGYGTRNDIAVLERPDGPPIVLAALSSR +DAADAAYDDALVARAAEVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas nasturtii TaxID=1843581 RepID=UPI0007E4ABC9 +---LRARWAEIERGTGGRLGIGLLDSATGWHI-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIHTADMLAHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP +AGLTAFLRGIGDAHTRSDRYEPEMNRFAAGDQRDTTTPAAMAATLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGPTREWKIGDKTGSNGTDTRNDIAILWPPEGAPLLLTTYLNG +AKVDAAAREAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia mikamii TaxID=508464 RepID=UPI0007C650CF +-----AEFRDLEARLHGRLGVYALDTGTGRTV-EYRPDERFPYCSTFKALAAGALLSSLP +--PAELDRRVTYTRADLVPNSPVTEQHVDQGMTLREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRAVGDTSTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPSVAADDRD +VLTGLLRANTTGAALIRAGAPAGWQVGDKTGAGAYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDAEYDNAAIARAATIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia stercoris TaxID=2483361 RepID=A0A3M2LE54_9NOCA +--AVDAEFAAMEQEHGARVGLFAVDIRTGKTV-GYRADERFGMASTFKALAAAAVLRAHP +ISTGYLDQTVHFTSDDVVQDSPVTSKHLDSGMSIRELCDAAITYSDNTAGNLLLKQIGGP +QGLTAFARSIGDEVTHLDRWEPELDAMDPGDDRDTTTPAALTADYRALIFGDVLATPERD +QLTAWLVANKTGNARIRAALPPDWKTGDKTGTALYGSANDVAVTWPADGGPLVVAVLTTK +PDQAAAADNPLVAAVAKVAVT-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas translucens pv. poae TaxID=227946 RepID=A0A199P9P5_XANCT +--TLAQRLAGIERRAGGRLGVTLLD-GSGAVLgGQRQDERFPMCSTFKFVLAAAVLQRVD +RGELSLRQPVQIRAADMLSHAPVTERHVGGALSVAELCRATLIYSDNPAANLLFPLVGDP +PGLTRFLRGLGDTQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRALLLGDALQPASRE +QLAAWMLDNRTGDDCLRAGLPPGWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG +AKVDDAARDAALKAVAVAM---- +>[subseq from] Class A beta-lactamase n=1 Tax=Paracoccus kondratievae TaxID=135740 RepID=A0A5P8JLU4_9RHOB +---VTAAVRQAETELKARVGYAQLDLRSGNVT-GYREDERFPMLSTFKVLVCGAVLARVD +AGKEDLARHINYSATQLVDYSPVTEKHVDDGMTLSALCEAAITMSDNTAGNLLLEAVGGP +EGLTSFLKATGDNIGRLDRWETELNSAIPDDRRDTTTPNAMAKTLHRLLFGDVLSDQSRD +QLLNWMQNDRVADALLRAALPQGWYIADKSGAGDRGARAIVAALGPNGAPERIMVIYMTE +TDAALDERNAQIAKIGKALIANw +>[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. B2-1-3A TaxID=2589971 RepID=A0A504BR34_9RHIZ +------KIRRIEAKSGGRLGVACRIAGTAVQF-GYRENELFPMCSTFKTLAAAFILHRVD +GGIEQLDRSIEVPHNAVVANSPTTKNHAGGVMTVAQLCEAAVTVSDNGAANLLLASFGGP +PQLTAYLRSIGDTVTRLDRIEPELNESVPGDPRDTTSPLAMIEDYERLTLGDSLSQKSRA +QLVDWLVANKTGDDRIRAGLPKGWKCGDKTGTGEHGSTNDAAVIWPMSGNPVLMSVYLTG +TKQSLAKRNATIASVSRALVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Terribacillus saccharophilus TaxID=361277 RepID=UPI000BA60BE5 +-----ASFSSLEETYDARLGVFAIDTGSGRTV-AYRENERFGFASTHKALSVGVLLQQKS +--MEDLNKRIMFTGDDLVNYNPITEKHVDSGMTLKELSEASISYSDNTAANLIFEEIGGP +DGLEDGLRKIGDQVTNSERIEPDLNNTQPGDTRDTSTPKAMAKSLREYALGDHLSADKRQ +LLIDWLKGNTTGDALIRAGVPKDWEVGDKTGAGSYGTRNDIAILWPPDEEPIVLAIMSDH +DEADANANDDLIAEAAEAAV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD196 TaxID=1053243 RepID=R8GNX0_BACCE +-eQTHQKFSQLEKEFDAKLGIYALDTSTNQTV-IYNPNERFAYASTHKALAVGVLLQKKS +--IEDLDQRIMYTDKDLVNYNPITEKHIDRGMTLKELADASLRYSDNTAQNLIFKQIGGP +DGFKKALQEIGDTVTNPQRIEPELNDVNPGETPDTSTPKALAASLQTFILGDVLPTEKRN +LLIDWMKRNTTGDKLIRAGVPKGWEVADKTGAASYGTRNDIAVIWPPNKKPIVLAILSNR +DKKEAKYNDQLIAEATKIALD-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas vasicola pv. vasculorum NCPPB 206 TaxID=1094181 RepID=A0A5K1MYY9_XANVA +---LRAQWAEIERGTGGRLGISLLDSATGWHL-GQRQDERFPMCSTFKFVLAAAVLQRVD +QGKLMLAQRVKIRASDMLEYDPVTERHIGGSLSVGELCRATMIYSDNPAANLLFPLVGDP +AGVTAFLRSIGDAQTCSDRHEPDMNRFAAGDPRDTTTPAAMANTLRTLLLGDALRPASRK +QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGIDTRNDIAILWPPKGAPLLLTAYLNG +AKVADAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhizobium sp. ERR 942 TaxID=2572676 RepID=A0A560M106_9RHIZ +----EAQLAALESKHPGRICVSILDLASGKRI-EHRAGERILMCSTFKALAAALVLARVD +KGDEKLDRRIHYKKSDLVDYSPATEPNTGDNMTVGELCAAAVTLSDNTAANLLLASFGGP +KAVTAFCRSLGDDLTRLDRTEPTLNYDTPDDQRDTTTASAMLENLRRLLFTDILTAASRS +QLAAWLITNKTGDTRLRAGLPKDWLVGDKTGTNGYGNANDIAVLWPSKHAPIIVTAYCEI +PAIAADERNAIIAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. Soil745 TaxID=1736396 RepID=UPI0009EC948A +--ATIKKFEQLEKEYDAKLGVYAIDTGTKKTV-EFHENERFAFTSTHKALAVGALLHQES +--IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP +AGFKKELEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DEKEADYNDELIAEATEEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=UPI000767D9B9 +--AFTGAFKKLEHAYDARLGVYAIDTGTGREV-AYRDGERFAYASTFKALAAGAVLRKYS +--LSGLDRVIRYAKDDLVDYSPVTEKHVKTGMTLGALCDAAVRYSDNTAANLLFDVLGGP +KGLDAMLEKMGDDVIQMENEEPELSRWVPGETHDTSTPRAMAEDLRAFVLGDALGKPERA +RLTKWLRTNTTGDELIRAGVPKGWVVGDKTGNGSYGARNDIAVVWPPDSAPIVLAIMSWR +GDKDTPFDNKLIADAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0007DB2B66 +--AFTGAFKKLEHAYDARLGVYAIDTGTGREV-AYRDGERFAYASTFKALAAGAVLRKYS +--LSGLDRVIRYAKDDLVDYSPVTEKHVKTGMTLGALCDAAVRYSDNTAANLLFDVLGGP +KGLDAMLEKMGDDVIQMENEEPELSRWVPGETHDTSTPRAMAEDLRAFVLGDALGKPERA +RLTKWLRTNTTGDELIRAGVPKGWVVGDKTGNGSYGARNDIAVVWPPDSAPIVLAIMSWR +GDKDTPFDNKLIADAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF84C1F +----KHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASNHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPKLNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH +AKEDAKYEDKLIADATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ag82_G6-1 TaxID=1938853 RepID=A0A286CBL9_9ACTN +----TARLRDLEREHTARLGVYGRNLRTGRTV-VYRAGERFPMASVFKTLAAAAVLRDLD +RDGEFLARRVHYTQEYVTKYSPITKDHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP +TAVTRFARSVGDRVTRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGTALEPRDRA +RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNNDVGITWPPDGPPIVMSVLTTQ +PEEDAPADNPLVAGAAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. NRRL WC-3656 TaxID=1463824 RepID=UPI0004C42603 +-----AEFHDLEARLHGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP +--PAELDRRITYTRADLLPNSPVTEQHVDQGLTLREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYALDPAVAADDRD +VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGNYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDAEYDNAAIARAATIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. M56 TaxID=1495638 RepID=A0A2K8RG90_9ACTN +--AFTGEFKKLERAHDARLGVYAIDTGTGHEV-AYRDGERFAYASTFKALAAGAVLRKYS +--LSGLDRVIKYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDELGGP +GGLDAILEKMGDDVIQMEHYEPELSRWVPGATADTSTPRAMAEDLRAFVLGDVLGKGERA +QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGSGSYGARNDIAVVWPPDAAPIVMSIMSYR +GDKDADYDEKLIAEAASVVAD-- +>[subseq from] Class A beta-lactamase n=3 Tax=Streptomyces TaxID=1883 RepID=A0A6B1M571_9ACTN +--AFTGEFKKLERAHDARLGVYAIDTGTGHEV-AYRDGERFAYASTFKALAAGAVLRKYS +--LSGLDRVIKYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDELGGP +GGLDAILEKMGDDVIQMEHYEPELSRWVPGATADTSTPRAMAEDLRAFVLGDVLGKGERA +QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGSGSYGARNDIAVVWPPDAAPIVMSIMSYR +GDKDADYDEKLIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia rhamnosiphila TaxID=426716 RepID=UPI0004C44F5A +----TQQFADLEAAHGARLGVFALDTADGRSV-AYRDGERFPMASTFKGLACGALLHKHP +LSSGFFDRVIQYPRTDLVENSPVTEQHVDTGMTVAALCEAAITVSDNTAGNQILKLLDGP +AGFTAFLRALGDTTSRLDRWETELNTAIPGDERDTTTPAALVADYRALVVGDSLAEPERA +QLSAWLVASATGGNRIRAGLPAGWKVGNKTGSPAYGSALDVAVAWPPGRAPLVIAVLTTK +SEQDAEPDNALVAAAARAAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. BK447 TaxID=2512159 RepID=A0A4R7IY66_9ACTN +-----NELEELERKFDARLGVYAIDTGTGREV-AYRDGERFGYHSTFKALEAGAVLRKYS +--LSGMDKVVRYSEDDLVANSPITEEHVETGMTLSELCDAAVRYSDNTAANLLYEELGGP +KALEAELRKLGDQVTSMDRIEPDLSNWVPGETRDTTTPRALAKDLRAYVLGDVLRKRERA +QLTTWLKTNTTGNEVIRAGVPEGWVVGDKTGSGGYGARNDIAVVWPPDSAPIVMAILTNR +GKADDTHDNKLIAEAASVVADK- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. KC06 TaxID=2530369 RepID=A0A4R4XUP3_9ACTN +--DVTAKLRGLEKARDVRIGAYAVDTGTGRFV-GHRADETFPFASTFKAIVCGAVLRKAD +SDPGLLDRVIRYKKSDLAPFSPVTEKHVGTGMTVADLCHATITRSDNAAGNLLLKQIGGP +SGLTAFLRSLGDTVSRSDRWEPGLNDWKPGERRDTTTPRAWAGSLRALTVGDALAPADRD +RLIGWLKAAVTGGARIRAGLPEGWTAGDKTGTAGYGSANDIAIVWPPSRAPLVIAILTTR +PGAGAEADERAVAETARVLTQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DBF8AAB +----DQEFRRLEEQFGARLGIHAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT +--DAQLDRVVRYSARDLVAHSPITEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +AGFEAKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALEPADRD +VLRGWLRGNTTGAALVRAEVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DRKDATPDDAVIAQATRVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces angustmyceticus TaxID=285578 RepID=A0A5J4LLU1_9ACTN +-----AALRRLEHAHRARVGAFAHNTVTGATA-AYRAHARVPLCSVFKTLAVAAVLRDLD +RDGETLARRIRYTAADLVDNSPVTERHVATGLTIADLCAAALRRSDNTAANLLLRELGGP +AAVTAFARSLGDRTTRLDRWEPDLNSAEPWRTTDTTSPAAIGTAYARLLVGDALAPSDRG +RLTAWMKGNETSAHRFRAALDEDWTVADKTGTGSYGTGNDVGVAWTPDGTPIVLAVLTSK +PEQAADADDALIASVTRVLVR-- +>[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. M7D.F.Ca.US.005.01.1.1 TaxID=2493678 RepID=A0A3S9DZ19_9RHIZ +---VLPKIRRIEAKSGGRLGVACRIAGTSAQF-GYRENELFPMCSTFKTLAAALILHRVD +SGIEQLERSIKIPHNAIIANSPTTKKFAGGEMTVAQLCEAAVTVSDNGAANLLLESFGGP +PQLTAYLRSIGDSVSRLDRIEPELNESLPGDERDTTSPLAMVEDYQRLALGTSLSDKSRA +QLVEWLVANKTGDERIRAGLPKGWRCGDKTGTGDRGSTNDAAVIWPASGNPILMSVYLTG +TKQSLTKRNAVIASVSRALVE-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00081B7B06 +--DTADAFEKLEAEFDARLGVYAVDTGTGREV-THHADERFAYASTFKALAAGAVLRTYK +--VSGMDRVITYSEDDLVPDSPVTEKHVGTGMTLDALCDAAVRYSDNTAANLLLDRLGGP +KGLGALLAELGDGVTRMERLEPELSRWVPGSTRDTTTPRAFAENLRAFVLGDVLGDAERA +RLTRWLRTNTTGDEVIRAGVPDNWAVGDKTGSGGYGIRNDIAVLWPPDRAPVVVAVLTNR +DGEGDAYDNRLLAKAAAVVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A0L1LT32_BACME +---SDREFAKLEDKYDANLGVFALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLDERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKGAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A3D8X0J5_BACME +---SDREFAKLEEKYDAKLGVFALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLEELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGEIHDTSTARALAASLQTYVLGQALPEEKRE +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSNR +TEKDAQYNDELIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 2231.1 TaxID=1855347 RepID=A0A1H5GYV7_9ACTN +---VEAELRDLEQRYDARLGVYARNVRTGRTL-SHRAGERFAMCSTFKAFAAAAVLRDRG +-DRAPLDRVIHYPPHDILPNSPRTQENLATGMTVGDLCAAAIQYSDNAAGNLLLREIGGP +AGLTRFLRSLGDDVSRLDRWEPELNTAIPGDLRDTTTPRAIGGSLARLGLGRALGDADRE +RFVGWLKGNTTSTGRFRRGLPDGWVLADKTGTGSYATANDIGVAWTARRTPVVLAVLSTR +STEDATVDEALVAEAARVIAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Franconibacter pulveris TaxID=435910 RepID=UPI000489FA96 +--QLTAAAQQEEKTLNARIGVAVLDTATGKTA-SYRGDERFPLNSTHKALLCGALLKQAD +EKKVSLTEAVRFDKSRLVEYSPVTEKHTAPQMNWLQLCSAAVSYSDNTAANLISQKVGGP +QGVNAFLRANGDKTTRLDRVEPALNEARPGDERDTTTPQAISRTLQTLLLGDALSEASRK +QLTRWMIDDKVADALLRQSLPKGWTIADKTGAGGYGSRSIISMVWPEKGTPLVVAIYITQ +TDASLSQSNAAIARLGHVIFQQ- +>[subseq from] Beta-lactamase n=1 Tax=Marinospirillum alkaliphilum DSM 21637 TaxID=1122209 RepID=A0A1K1XG11_9GAMM +--ALVTELQRIESDLKARIGFSAHDLETGLRW-EHHADQRFAMSSTFKTLACAALLQQVD +ENEVQIERKISFSEADLVTYSPVTEQHAGQRMSLFELCEATMTTSDNTAANLILQAIGGP +EAVTEFVRGIGDDVTRLDRWETELNQATPDDERDTTTPNAMVANLEALLLGNVLSPSSRG +QLREWLVGNKVADGLFRSSMPADWVIADRTGAGGFGSRSITAVIWPPERLPVVVAFYITE +TTASFDDRNAAIAALGRVIK--- +>[subseq from] Beta-lactamase n=1 Tax=Terribacillus halophilus TaxID=361279 RepID=A0A1G6JAM9_9BACI +---TQEPFADLEKTYDAHLGVYAVDTGSGKTV-AYRENERFGFASTHKALSAAVLLQQNS +--LEDLNKKIMYTSDDLVNYNPITEKHVKSGMTLKELAEASVSYSDNTAANLIFEEIGGP +AGLKQALRDIGDQVTEPARIEPELNNVKPGETQDTSTPKALAESLRAFTLEDSLSPENRQ +LLIDWLKGNTTGDNLIKAGVPKEWEVGDKTGAGSYGTRNDIAILWPPDSEPIVMAIMSSR +DEADASYDDALIAEAAQEVV--- +>[subseq from] Beta-lactamase CTX-M-1 n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6D1P2K5_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRA---------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces californicus TaxID=67351 RepID=UPI0004AA4345 +----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLDKYS +--LDGLDQRVTYTRKELVANSPVTEKHVGTGMTLKELCDASVRYSDNTAANLLFDHVGGP +RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLGEALPAPERE +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR +ATKDAEPSDELIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces argenteolus TaxID=67274 RepID=A0A561QBY3_9ACTN +--RTARAFRELERTFDARLGVYALDTGSGRTV-THRADERFAYASTCKALLAGAVLSRNS +--LRQIDRLVRYDRDDLISNSPITERHIATGLTLRELCDAAVRYSDNTAANLLFRELGGP +QGLQDALRAEGDNVTRCDRYEIALSDAVPGDVRDTSTPRALAHDLRTYVLGTTLPADKRT +VLTDWLKRNTTGDHTIRAGTPDGWQVGDKTGSGGYGTRNDIAIIWPPDAAPITLAVLSRR +DTKDAERDDALIARAAEVALR-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. XY152 TaxID=1415560 RepID=UPI0006ADEBC7 +----APEFRALEREFDARLGVYALDTGTGRSV-GYRADDRFAYASTFKALAAGAVLRKHG +--TGGIDKVVTYARGDLVAYSPVTENFVGTGMSLRDLCAAALWYSDNTAVNLLLDELGGP +DGLEKVLEEFGDDVTEMDRYEPELNDAAPGDIRDTSTPRAMAESLRAFLLGDALKRDERE +LLRQWMTTNTTGRTLIRAGVPDGWDVADKSGSAGYGGRNDIAVVWPEDGDPVVMAVMSTR +GKEGADRRDALVAKAATVAAD-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=UPI00140FD3CB +-----PDFTALEAASGGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKFVLCAAVLRQVD +AGRLDLDKRVPMRAEDLIDHAPVTRRHIGKDLTVRDLCRATMITSDNPAANLLLGVVGGP +PAVTRFLREHGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRFLLGQVLAPASRQ +QLADWLIDNETGDERLRAGLGSTWRVGDKTGSNGKDTTNDIAMLWPMGGTPWVLTSYLQG +ATVDDAGRNDVLRQVAV------ +>[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus vietnamensis TaxID=351656 RepID=A0A1Y2SAX8_9GAMM +--EIIDQLSMLEKNANGRLGVVLIDTSDHSTI-TYRANERFPLCSTSKLMVASAILKKSE +INTHLLNQRIHYQQSDLVEYSPITEKHLKDGMTLGELSAATLQYSDNTAMNLLLNQLNGP +SEVTKFARAIGDNHFRLDRQEPELNTAIPGDERDTSTPQAMAKSLYNLALGNALATTQRE +QLIEWLKGNTTGNTSILAGVPKGWVVGDKTGRCDYGTTNDVAVIWPPKRAPLVLVTYFTQ +PDQEGRARPDVLAAAARIMTQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 6-11-2 TaxID=2585753 RepID=UPI001143DFA3 +---TTARLRALEQGHGARLGVFAHNPATGRTV-RYRADERFPMCSVFKTLAAAAVLRDLD +RHGKVLSRRVHYTEADLVLGSDQTRAHLATGMTIAELADVAIRFSDNTAGNLLLRELGGP +TAVTRFARSLGDPVTRLDRWEPDLNTAEPWRLTDTTSPRAIGRTYARLVLGDALNRDDRR +LLTRWLLNNTTSANRFRAGLPPTWTVADKTGSGAHGTTNDVGVAWTRSGSPVVLAVLSTK +PARDAPYDDALVARTAAAVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB01373 TaxID=2020325 RepID=A0A2M9IRS3_9ACTN +---TTARLRALEQEHGARLGVFAHNPGTGRTV-RYRAEERFPMCSVFKTLAAAAVLRDLD +RHGEVLSRRVHYTEADLVPGSDQTRAHLATGMTVAELADVAIRFSDNTAGNLLLRELGGP +TAITRFARTLGDPVTRLDRWEPDLNTAEPWRLTDTTSPRAIGRTYARLVLGDALNRRDRR +TLRHWLLNNTTSTHRFRAGLPPTWTVADKTGTGAHGTANDVGVAWTESSSPVVLAVLSTK +PAQDAPYDDALVARAAAVVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Corynebacteriales TaxID=85007 RepID=UPI0007EA87E1 +-----AEFHDLEARLHGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP +--PAELDRRITYTRADLLPNSPVTEQHVDQGLTLREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPAVAADDRD +VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGSYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDAEYDNATIARAATIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia nova TaxID=37330 RepID=A0A2S6AG86_9NOCA +-----AEFHDLEARLHGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP +--PAELDRRITYTRADLLPNSPVTEQHVDQGLTLREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPAVAADDRD +VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGSYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDAEYDNATIARAATIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia nova TaxID=37330 RepID=UPI000CEA1ECB +-----AEFHDLEARLHGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP +--PAELDRRITYTRADLLPNSPVTEQHVDQGLTLREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPAVAADDRD +VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGSYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDAEYDNATIARAATIAI--- +>[subseq from] Beta-lactamase n=2 Tax=Nocardia sp. 852002-20019_SCH5090214 TaxID=1834087 RepID=A0A1A0KK32_9NOCA +-----AEFHDLEARLHGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP +--PAELDRRITYTRADLLPNSPVTEQHVDQGLTLREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPAVAADDRD +VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGSYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDAEYDNATIARAATIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillaceae bacterium MTCC 10057 TaxID=590062 RepID=UPI0005896971 +--NTNERFIQLEKEFDAQIGVYAIDTGTDQTI-EYRPEERFAFASTYKALAAAILLKQNS +--LEELEKVITYTEDELVPYSPVTEKHVDTGMTLLELGEAAVRFSDNTAGNLLFEAVGGP +QGFEQALRQIGDDVTEADRLEPDLNKFTPGDTRDTSTPRALATSLQAFAVGGLLSGDERE +LFTDWLKGNATGDPLIRAGAPEGWEVGDKSGAGSYGTRNDIAVVWPPNRKPIVMAVLSRH +HTEDAAYDDELIAQAAKITLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus atrophaeus (strain 1942) TaxID=720555 RepID=A0A0H3E3D2_BACA1 +----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +NGFEKSLKQIGDHVTKSNRFETDLNSAIPGGIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus sp. lzh-N1 TaxID=2069255 RepID=UPI000C80E6DA +-----VVFKQLEIKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS +--NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP +EGFEKAMRDNGDNVVMANRYETELNEAIPGDHRDTSTPNALANSLKVLTIDDSMPNDKQE +LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR +DTKDAEYNNALIAEAAKAAFK-- +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillus sp. M-152 TaxID=2487928 RepID=A0A3G8RGI2_9BACL +-----VVFKQLEVKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS +--NDGLGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP +EGFEKAMRDNGDTVVMANRYETELNEAIPGDHRDTSTPNALANSLKLLTIDDSMPNDKQE +LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR +DTKDAEYNNALIAEAAKAAFK-- +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. CCH9-E1 TaxID=1768768 RepID=UPI00082E4FF2 +-kALSSRINELERASGGRIGVAVLDTQDGRRF-AWRGDERFRMCSTVKAPLSAAILRRVD +QGRERLDRRVTFGPEVLMGNSPIVEKHVQDGLTIGQLCEATITLSDNAAANLLFEALGGP +AALTRFLRAIGDQTTRSDRLEPALNGGAPDDPRDTTTPSAIVATWKALLLDDALSPASRQ +RLRDWLIANKTGDRRLRAGLPPGWRVGDKTGNNGKDITNDVAIAWPPGRGPVLIGVFHDR +GG-DEDARNTVHANVARAVVA-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces albulus TaxID=68570 RepID=A0A401QVG6_STRA9 +--SFEGELQELERRYAARLGVYARNARTGQVV-AHRARERFAMCSTFKTVAAAAILRDHA +-RCAPLDKVIHYPPADLLANSPRTAEHVDTGMAVGDLCAAAIQYSDNTAANLLLRQIGGP +AGLTRFFRSIGDRESRLDRWETELNDAVPGDLRDTTTPEALGTSYGRLTVGRALDPAARE +HLVTWLKGNTTSGERFRAGLPHDWVVGDKTGTGDYASANDVGVAWTTRQTPIVLAVLTSK +DAKDAPVDNALIADAARIVAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI000B43D9FA +----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +NGFEKSLKQIGDHVTKSNRFETDLNSAIPGGIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVALN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella sp. TaxID=576 RepID=A0A2D2CI77_KLESP +-----EQIKLSESQLSGRVGMIEMDLASGCTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERN-------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces bacillaris TaxID=68179 RepID=UPI000DD6F932 +---TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLSGAVLARKS +--LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP +RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR +DVKDAESDDALIAGAAKVALEAf +>[subseq from] Beta-lactamase n=1 Tax=SAR86 cluster bacterium TaxID=2030880 RepID=A0A2A5B844_9GAMM +-----ATAIEIEKRLGARLGLAVIDEETGKRW-NYQADQRFPMCSTFKAIAVGAVLAQVD +KGEDSLNRVVNIAEGDLVSYSPVTENRLGGTMTLAEICEAALTMSDNTAGNKLLESIGGP +DGLTAFARLIDDNVSRLDRWETGLNEAAIGDVRDTTSPEAMSQTLRSLLLGDVLSSNSRE +QFKEWMVNNKTGDAKLRAGVPSSWQVGDKTGGGNNGTMADIAIIWPPNRKPLSIAVYMTE +TDASFDDRNLGISEIAAAL---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces caelestis TaxID=36816 RepID=A0A0M8QFM4_9ACTN +----APEFRALEREFDARLGVYALDTGTGRSV-GYRADDRFAYASTFKALAAGAVLRKHG +--TGGIDKVVTYARGDLVAYSPVTENFVGTGMSLRDLCAAALWYSDNTAVNLLLDELGGP +DGLEKVLEEFGDDVTEMDRYEPELNDAAPGDIRDTSTPRAMAESLRAFLLGDALKRDERE +LLRQWMTTNTTGRTLIRAGVPDGWDVADKSGSAGYGGRNDIAVVWPEDGNPVVMAVMSTR +GKEGADRRDALVAKAATVAAD-- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax ebreus (strain TPSY) TaxID=535289 RepID=B9MI58_ACIET +-qQLQAALGRVEQRVGGRLGVAVLDTGSDALA-TYRGDERFALCSTFKLLLAGQVLQRAD +QGLERLDARVRYGRHDLVEYSPRTEPHAGGAMTVAELCEATMVLSDNSAANLLLRRQGGP +AGLTAWLRTLGDAHTRLDRIEPALNDVPAGELRDTTTPRAMVHTVQKLVLGDALSGEARA +RLQGWLLGNLTGDKRLRAGMPAGWRIGEKTGTAN-GTSNDVGVVWPEGGAPAVVACYLTQ +CPAAPAQRDAAIAEVGSLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis chromatogenes TaxID=280239 RepID=UPI00034AC9C8 +--QADADFADLEEEFGARLGVYAIDTGSGEEV-AYNADQRFAYASTFKVPACGAVMEEYS +-LKEMRKHVVHFDEEDLVDYSPITEDHVDSGMTLMEVCDAALRYSDNTAANLLLEELGGP +EGFQEAMRELGDDTTISARWETELNENKPGDERDTTSPRAFAQNLEEYVLGDVLEKKERK +ALADMMVRSTTGDTLIRAGVPKNWKVGDKSGMPGYGGRNDIAVMWPPKGDPIVLAVYSTK +DTEDAESEDALVAQAAEVAV--- +>[subseq from] Beta-lactamase n=1 Tax=Pantoea anthophila TaxID=470931 RepID=A0A506P6C4_9GAMM +-qSLNNQFEKLERQSGGRLGLAVIDTSDSTQY-SWRGNERFPLCSTSKVMAVAAILKKSE +NADTLLNKKIHISQRDMVNYNPVTMKHIGSAMSLAELSAAALQYSDNAAMNKLLAYLGGP +QHATQFARTLGDTTFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNKLILGSALKDDQKA +TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPIVLTTYFTQ +HDKSAAARKDVLASAARVIAD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A0J7EFX0_9BACI +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMNLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia nova TaxID=37330 RepID=UPI000CE9E288 +-----AEFHDLEARLHGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP +--PAELDRRITYTRADLLPNSPVTEQHVDQGLTLREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPAVAADDRD +VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGSYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDADYDNATIARAATIAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL WC-3549 TaxID=1463925 RepID=UPI0004C91FB8 +------AFGGLEEKYGARLGVYALDTGTGREV-THNADERFAYASTFKALAAGAVLRTYE +--VSGMDWLVTYSEDDLVPDSPVTEKHLATGMTLDALCDAAVRHSDNTAANLLLERLGGP +KGLNVLLRQLGDDVTRMERLEPELSRWEPDSTRDTTTPRAFAGNLRAFVLGDVLGDAERN +RLTHWLRTNTTGDELIRAGVPEDWTVGDKTGAGGYGVRNDIAVLWPPDRAPVVVAIMSNR +GRADAPYDNRLIAEAAAVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Inquilinus limosus TaxID=171674 RepID=UPI000417B29F +----GARLAELERAQGGRLGVAVLDLATGARI-GHRADERFLLCSTFKALAAAFVLARVD +QKKEQLDRRVVFSRKDIVAGPSVIEHRVGGAITMAELCDAAVTYSDNTAGNLLLASFGGP +PALTAFLRSLGDEVSRLDRTEPELNAAGPGDPRDTTTPAAVLETLRKLLFGDALSRRSRD +QLAAWLITNKTGDTRLRAGFPADWLVGDKTGTGGEKSTNDVAIAWPPGRGAVIVTAYCEL +PSASFEQRNAVVAEIGRIVSQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sontii TaxID=2650745 RepID=UPI00129A8F0A +--TLPQRLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD +RGELALERRVPVRKADLLANAPVSERHVGGTLSVVELCRAAMIYSDNTAANLLLPLVGDP +PGVTRFLRALGDAQTQLDRNEPGMNAFVAGDPRDTTTPAAMAATMRALLLGDVLQPVSRQ +RLIAWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG +ATVDSAARDATLKAVAQAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0012B90387 +---SDREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQTYVLGQTLPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR +TEKDAEYHDKLIAEAAKQAVK-- +>[subseq from] Carbapenem-hydrolizing beta-lactamase SFC-1 n=1 Tax=Serratia fonticola TaxID=47917 RepID=Q6JP75_SERFO +-----DKLKRLENDFGGRIGVYAIDTGSNKTF-GYRANERFPLCSSFKGFLAAAVLSKSQ +QQEGLLNQRIRYDNRVMEPHSPVTEKQITTGMTVAELSAATLQYSDNGAANLLLEKIGGP +EGMTSFMRSIGDNVFRLDRWELELNSAIPGDDRDTSTPKAVAESMQKLAFGNVLGLTERH +QLMDWFKGNTTGGARIRASVPANWVVGDKTGTCGYGTANDYAVIWPVGHAPIVLAVYTSK +PDKNSKHSDAVIADASRIVLESf +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium zhanjiangense TaxID=1325107 RepID=A0A4Q0SUG0_9BRAD +------ELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGQADLLEYAPVAKQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSIGDTTSRLDHNEPELNRSRPGDPRDTTTPAAMAGNLRRLVLGEGLSPTSRA +QLTEWMVNCKTGANRLRGGVPAGWRIGDKTGNNGKDASGDIAVVWPRPDAPILIAAYTQG +GTPSAAQIAAAFARIGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. ARC270 TaxID=2027923 RepID=UPI000DA780E8 +-qSLNNQFEKLERQSGGRLGLAVIDTSDSAQY-SWRGNERFPLCSTSKVMAVAAILKKSE +NADTLLNKKIHISQHDMVNYNPVTMKHIGSAMSLAELSAAALQYSDNAAMNKLLAYLGGP +QHATQFARTLGDTTFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNKLILGSALKDDQRA +TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPLVLTTYFTQ +HDKNAAARKDVLASAARVIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=UPI000767912D +---FTGAFRKLEHAYDARLGVYAIDTGTGREV-AYRDGERFAYASTFKALAAGAVLRKYS +--LSGLDRVIRYAKDDLVDYSPVTEKHVKTGMTLGALCDAAVRYSDNTAANLLFDVLGGP +KGLDAMLEKMGDDVIQMENEEPELSRWVPGETHDTSTPRAMAEDLRAFVLGDALGKPERT +QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGNGSYGARNDIAVVWPPDSAPIVLAIMSWR +GDKDTTFDNKLIADAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E1EB593 +--ELRYKWAEIQRGSGGRLGISLLNSDTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP +PGLTLFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDGCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAGRDAALKAVAEAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDD585C +-dEIDRRIAALEKQIGGSIGVSVIDTQTNISL-GYRETESFPLCSTFKVLAAGFVLARVD +KGEENLERRIIYDTDKLVTYSPETGKHVGGDMSVGDLCQAAITLSDNTAANLLLESFGGP +KELTNWLRTFGDASTRLDRWETDLNEGKKDDPRDTTTPDAMLDTLGNLTLGSVLSEPSQN +TLVEWMVANTTGGARLRPGLPDDWKIGDKTGTGNNGCAADIAIAWPPGHGPLLMTVYVKQ +ANVPVADINPVFAEVGRIVTD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q5MDA0_ECOLX +-----EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVADRVAGPLIRSVLPAGWFIADKPGASKRGARGIVALLGPNNKADRILVIYLRD +TPASMAERNQQI----------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL WC-3723 TaxID=1519491 RepID=A0A0M8XA35_9ACTN +----HAELAELERRYGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDQA +-DCAPMDRVVHYPPHDILPNSPRTEENLATGMTVADLCAAAIQYSDNAAGNLLLRELGGP +AGLTRFYRSLGDEVSRLDRWEPELNTAIPGDPRDTTTPEAIAASLERVTLGRALARADRE +RFVGWLKGNTTSSARFRKGLPREWVVADKTGTGDYATANDIGVAWTTRRTPLVLVVLSSR +TTPDAPVDEAPIADAAAVVAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00112BB390 +---SDREFAELEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDEVTLPERFEPDLNEVNPGETHDTSTARALAASLQTYVLGQALPEDKRE +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR +TEKDAEYHDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 70 TaxID=1827606 RepID=UPI000C1A9D07 +-aATGDRLRELEQQHGARLGVFAHNVRTKETV-DHRADELFPVCSLFKTLAAAAVLRDLD +RHGEVLARRIHYTEADLVDGSDRTREHLAEGMTVAELADVAIRYSDNTAGNLLLRELGGP +TAITRFARSIGDPVTRLDRWETELNSAEPWRVTDTTTPRAIGRSYARLVLGDALNRPDRE +LLTHWLLNNTTSGNRLRAGLPKTWTVADKTGAGSYGANNNAGIAWTPEGTPVVLAVQVTK +PERDAAWDHELIAEAAAVLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. Leaf78 TaxID=1736237 RepID=A0A0Q4RWE7_9BURK +--AWNDTLAGIERTAQGRLGVAMLDTGTGLAL-GWRQDERFAMASTFKAVLAGWMLALVD +QGKERLDARVHYAAADVVAYSPASGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDGMTRLDRTEPTLNEAKVGDPRDTTTPLAMLQTLQKLVLGDVLTPASRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTTNSGTSNDIAVMWPPGGAPVVVTCYITA +STASSEQRDAAIAQVARAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Roseomonas aestuarii TaxID=568898 RepID=A0A2U1V0N3_9PROT +--ALEARLRAIEAETGGRLGVAVREAAPGGLRaGHRAAERFPLTSTFKLLAAAAVLRRVD +AGQERLDRVLRFSSADLVTYSPVTRPQADGPMTLEALCAATVTLSDNTAGNLVLGTLGGP +AGLTAFARDLGDPVTRLDRWETALNEATPGDPRDTTSPEAMLGLIGALTLGEALSAASRE +RLMGWLLGNRTGDRRLRAGLPAGWRAAEKTGSGGRNTANDVGLLLPPGGAPILVTVYLTG +ATAPAEARDAAIAAVAEAVVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces halstedii TaxID=1944 RepID=UPI0013CC7409 +--ETAEAFEKLEGEFDARLGVYAVDTGTGREV-THRADERFAYASTFKALAAGAVLRTYK +--VSGMDRVITYSEDDLVPNSPVTGRHVGTGMTLDALCDAAVRHSDNTAANLLLDRLGGP +KGLGALLAELGDDVTRMERREPELSSWVPGSTRDTTTPRAFAGNLRAFVLGDVLGDAERA +RLTRWLRTNTTSDEVIRAGVPDDWTVGDKTGTGGYGIRNDIAVLWPPDRAPVVVAVLSNR +DGEDDAYDNRLLAKAAAVVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. AS23.2 TaxID=1680155 RepID=A0A1Q5RBZ5_9BRAD +------EIASYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGDEQLASMIPYGQADLLSHAPAAKQNLATGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSRPGDPHDTTTPAAMAGNLRRLVLGEGLSPASRA +QLTDWMVNCKTGANRLRGGLPASWKIGDKTGNNGKDAAGDIAVAWPKADTPILIAAYTQG +GTPSAAQIEAVFARIGRMVAE-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A212MHV7_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLKDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTT- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A1A9Q140_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVLYSDSTAHNLILKQLGGP +SEFEKILREMGDIVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus thuringiensis serovar coreanensis TaxID=180843 RepID=A0A193CSU8_BACTU +----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASKSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAEYDDKLIADTTKVVLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. LLH-Irr-9 TaxID=1564892 RepID=A0A097SRQ4_9ACTN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVFIYTTG +SRV-------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Ag82_G6-1 TaxID=1938853 RepID=UPI000BE3CAE0 +----TARLRDLEREHTARLGVYGRNLRTGRTV-VYRAGERFPMASVFKTLAAAAVLRDLD +RDGEFLARRVHYTQEYVTKYSPITKDHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP +TAVTRFARSVGDRVTRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGTALEPRDRA +RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNNDVGITWPPDGPPIVMSVLTTQ +PEEDAPADNPLVAGAAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI00096EAE32 +---LRARWAEIQRGTGGRLGISLLNSVTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHASVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP +PGLTRFMRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAGRDAALKAVAEAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseus TaxID=1911 RepID=UPI0004C4CCDB +--RAAARFRALEERYGARLGVHAYDVRTGRVL-AHRDRERFPMCSVFKTLAVAAVLRDLD +HDGSFLARRVHYTAADVERWSPVTGDNLARGMTVAELCDATLRFSDNTAANLLLRDLGGP +TAVTRFARSAGDPVTRLDRWEPELNSAEPWRTTDTTTPRAIARTYGRLLLGRVLDPADRA +LLTDWMLRNTTSDARFRKGLPADWTVADKTGGGDYGGNNDVGVTWPPDGGPILLAVLTTR +RDRDAEGVDELVAAAAAVAADE- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas oryzae pv. oryzicola (strain BLS256) TaxID=383407 RepID=G7TCU9_XANOB +--MLRAQWAEIECGTGGRLGINLFDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLTQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP +AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRT +QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ag109_G2-15 TaxID=1938850 RepID=A0A286HGJ4_9ACTN +----HAQLSDLEQRYGARLGVYAHNVRTGRTV-AYRAGERFAMCSTFKTFAAAAVLRDHG +-GCAPLDRVIHYPPRDILPNSPRTEEHLATGMSVGDLCAAAIQYSDNAAGNLLLRQIGGP +DGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPEAIGRSFERLTLGRALDGTDRE +QLVTWLKGNTTSAERFGRGLPQGWVLGDKTGTGDYATANDIGVAWTTRGTPIVLAVLSTK +AAKDAPVDNALVADTARLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces libani subsp. libani TaxID=68044 RepID=A0A640TG79_9ACTN +--RAAKALAQVERRYHSRLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAAVLLKRST +--DDELNRVINYRASDLEDYAPITKRHVGEGMTLRDLIKAAVQYSDNTAANLLLDRLGGP +AGLQKALRGMGDRTTRTDRTEPTLNEAKPGDPRDTSTPRALGTDLRRFVLGDVLPEGRRQ +LLTHVLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPAGGSPIVVAVLSDR +GSKDAASDDALIRDATKT----- +>[subseq from] Class A beta-lactamase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A525L175_9CAUL +--AAETRIKALEAELGGRLGVAALDTGTGRRI-AWRAHERFPMCSTFKLLAVSAILHRVD +TDCETLERQILVDKADVVGWAPVTEKHIGETLPLAMLCEAGITQSDNGAANLILTALGGP +QGVTGYARSIGDRTTRLDRREMALNEGTPGDPRDTTTPSATLGDMRKILTGKALTEVSRK +RLTDWLVADQMGGARIRAGAPAGWRIGDKTGTGGHNATNDLAILWPPGRAPILVAAYSHG +SPKPTDACQTALAEIGRIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Roseomonas deserti TaxID=1817963 RepID=A0A1V2GVP6_9PROT +---LEQRLAEIEARSGGRLGVAILVAGTARHA-GHRLDERFPLCSTFKVLAAAAVLARVD +AGQEQLDRPIRFTRDQLVAYSPGTEAGAGGPLPMRHLCEVAVTLSDNTAANLMLQSLGGP +AGLTAWLRGLGDATTRLDRIEPELNEGTPGDPRDTTTPLAMSQTLEKLILGNALKPDSRA +LLTRWLVENKTGDDRLKARLPSGWRAGEKTGTGPRGSTNDAGILWPADSAPLLVSAYLTG +TSAPLAARNAALAEVGKAVAEFy +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia asiatica TaxID=209252 RepID=UPI000A3074C8 +--ALTSSFAELETTHSARLGVYAIDSGTGRTV-VHRDGERFPIASTFKGLACGALLRDHP +LATGYFDQVIHYSRSELVANSPVTEKHVDTGMTVAELCDATITLSDNTAGNQLLKLLGGP +EGFTAFLRSIGDTVSRLDRWEPELNTAIPGDERDTTTAAALATDYRNLVLGDILAEPERE +RLKSWLVAAKTGGARIRAALPADWTVGDKTGSPAYGGALDVAIAWPPGRAPLVIAVLSTK +FEQNAEADNPLVAEAARAAI--- +>[subseq from] Beta-lactamase n=2 Tax=[Brevibacterium] frigoritolerans TaxID=450367 RepID=A0A561DJ87_9BACI +--ATIKKFEQLEKEYDAKLGVYAIDTGTKKTV-EFHENERFAFTSTHKALAVGALLHQKS +--IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP +AGFKKALEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDTLPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWAVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DEKEADYNDELIAEATEEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. LUP47B TaxID=1890286 RepID=UPI0009A048CD +--DITARLRALEERYDARLGVFAHHLATERSV-RFRAGERFPMCSVFKALAAAAVLRDLD +RDGEVLARRIHYTEDDLVIGSDQTAAHLAEGMTIAELAEVAITYSDNAAGNLLLRELGGP +TAITRFARSLGDGVTRLDRWEPELNTAEPWRHTDTTTPYAIGRTYGRLVLGDALNRRDRE +LLTHWLLNNTTSVNRFHAGLPKTWAIADKTGSGSYGTANDVGVVWTDDGDPIVLAVLSTM +PAQDAVRDDALIADAARAVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 196(2019) TaxID=2683820 RepID=UPI0013EB342B +---TDRAFAELERTFDARLGVYAVDTGDGRTV-THRPDERFAYASTCKALLAGAVLARKT +--LPQMERLVRYGQEEIISHSPITAKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP +RGLQDALRGIGDDVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LITDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR +DVEDAEPDDALIAGAARVALEAf +>[subseq from] class A beta-lactamase n=1 Tax=Terribacillus saccharophilus TaxID=361277 RepID=UPI000BA4EBE9 +-----ASFSSLEETYDARLGVFAIDTGTGRTV-AYRENERFGFASTHKALSVGVLLQQKS +--MEDLNKRIMFTGDDLVNYNPITEKHVDSGMTLKELSEASISYSDNTAANLIFEEIGGP +DGFEDGLRKIGDQVTNSERIEPDLNNTQPGDTRDTSTPKAMAESLREYALGDHLSADKRQ +LLIDWLKGNTTGDALIRAGVPKDWEVGDKTGAGSYGTRNDIAILWPPDEEPIVLAIMSDH +DEADAKADDDLIAEAAETAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000E0F8B12 +--MLRAQWAEIERGTGGRLGISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQPVKIRAADMLEHAPVTKRHVGGALSVGDLCRATMIYSDNPAANLLFPLVGGP +PGVTAFLRSIGDAKTRSDRYEPAMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTRGWKIGDKTGSNGTDTRNDIAILWPPQGPPLLLTTYLNG +AKVDDAARDTALKAVAVAVREW- +>[subseq from] Beta-lactamase n=1 Tax=Rhodovulum sp. TaxID=34009 RepID=A0A2E2JWK5_9RHOB +---ISAELARIEQALDARIGFAAHDLATGQRW-EVNADERFAMSSTFKTLACGALLEQVD +EGLLAPDTEVSFDESALVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLILEALGGP +EAITAFARRLDDSVTRLDRFETELNEATPGDERDTTTPNAMLATLETLVLGDVLTPESRQ +QLQDWMKGNAVADGLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQAPTVAVFYLTE +TDASFEARNEAIASLGEVVQ--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia nova TaxID=37330 RepID=UPI000CEA1376 +-----AEFHDLEARLHGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP +--PAELDRRITYTRADLLPNSPVTEQHVDQGLTVREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRAIGDPTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPAVAADDRD +VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGDYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDAEYDNATIARAATIAI--- +>[subseq from] Beta-lactamase n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A1C6MSW2_9ACTN +---TDRAFAELERTFDARLGVYAVDTGDGRTV-THRPDERFAYASTCKALLAGAVLARKT +--LPQMERLVRYGQEEIISHSPITAKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP +RGLQDALRGIGDDVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LITDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR +DVKDAEPDDALIAGAARVALEAf +>[subseq from] Class A beta-lactamase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A3A4RHS1_9BURK +---VQDALRDIEATARGRLGVHIIDTATGREQ-GWRADERFLMLSSFKLLASALVLARTD +RGEESLERRIRYRAQDLVPWSPVTEQHVGGELSLAQLCEATLTTSDNTAANLILASYGGP +AALTAFARRLGDTVTRLDRTEPELNRAASGEPLDTTTPRAMAHTVRTLLLGDALSPASRE +RLLQWLLANTTGGKRLRAGVPAGWRVGEKTGTAGD-DANDVGIAFPPQRAPLIVTAYLAE +SATDGATRDAALASVGRLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB00316 TaxID=1703932 RepID=A0A1Q5EVF2_9ACTN +---TDRAFAELERTFDARLGVYAVDTVDGRTI-THRPDERFAYASTCKALLAGAVLAKKT +--LPQMERLVRYGRRDLVSYSPIAEQHVATGMTLRALCDAAVRYSDNAAANLLFRELGGP +RGLQDALRGLGDRVTRCDRYEVALSDATPGDPRDTSTPRALATDLRAYVLGSALPAEKRA +VLTDWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVWPPGGAPIALAVLSRR +DTKDAEPQDALIAGAAKVALGAf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 69 TaxID=1827605 RepID=A0A2N0J4Q6_9ACTN +---TRAELTDLEQRYGARLGVFARNLRTGQTV-AYRAGERFAMCSTFKAFAAAAVLRDQA +-DCAPLDRVIHYPPRDILPNSPRTEENLATGMSVHDLCAAAIQYSDNAAGNLLLREIGGP +DGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPEALGRSFERLTLGRALDPADRE +QLVTWLKGNTTSKKRFGAGLPQDWVLGDKTGTGDYATANDIGVAWTTRRTPLVLAVQSTK +AAKDAPVDDALIADTARVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=UPI00094A0865 +--MLRSQWAEIERGTGGRLGINLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDS +AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRK +QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=A0A1H2HN89_9PSEU +--QFHDRLMELEKKYDARLGVYALDTGDGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVRYSRADLMKHAPVTERHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +AALTAFTRGLGDTVTRMDRIEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLAADKRD +FLRDLLQRTVTGAGRIRAGLPPGWTVAGKTGTGEYGTLNDIAVLWPPGKAPIVLAVMSSK +AAKDAPYDEALLAEAAKYVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNS606 TaxID=1305837 RepID=UPI000D119547 +--RLARRLTELENRHAARLGVFAHDTATGRSV-QYRAQERFPMCSVFKTLAVAAVLRDLD +RHGEFLARRVRYDEKTVTDYAPVTGKHLAHGMTVEELCDAAIRYSDNAAANLLLRALGGP +RAVTRFCRSVGDRVTRLDRWEPELNSAEPGRRTDTTTPRAVAGTYARLTLGDALDRGDRR +RLTGWLLGNTTSGAKFRAGLPDGWAVADKTGGGEYGTNNDVGLTWPPGHPPIVLAVLTTR +FTPDAERIDPLVAEAASLVAA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces phyllanthi TaxID=1803180 RepID=A0A5N8WHX8_9ACTN +----AGALKELEREYDARLGVYAIDTGTGREV-AYRAGERFGYHSTFKALQAAAVLRKYS +--LNGMNEVIRYSEDDLIANSPVTEKHVETGMTLRELCDAAVRYSDNTAANLLYDKLGGP +KALEAELRRLGDKVSRMDRIEPELSKWVPGEKRDTTTPRALAKDLRAYVLGDVLGKRERA +QLTKWLKTNMTGDELIRAGVPEGWVVGDKTGSGYYGARNDIAVVWPPDSAPIVMAILTNR +GEEDDTYDNKLLAEAASVVA--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85) TaxID=291331 RepID=Q5H347_XANOR +--MLRSQWAEIERGTGGRLGINLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDS +AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRK +QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BFB8BD2 +---SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWTPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI0004E0AF1E +--EMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE +LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVMK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ag82_O1-9 TaxID=1938856 RepID=A0A3D9W6T4_9ACTN +----HAQLSDLEQRYGARLGVYAHNVRTGRTV-AYRAGERFAMCSTFKTFAAAAVLRDHG +-GCAPLDRVIHYPPRDILPNSPKTEEHLATGMSVGDLCAAAIQYSDNAAGNLLLRQIGGP +DGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPEAIGRSFERLTLGRALDGTDRE +QLVTWLKGNTTSAERFGRGLPQGWVLGDKTGTGDYATANDIGVAWTTRGTPIVLAVLSTK +AAKDAPVDNALVADTARLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Kosakonia sacchari TaxID=1158459 RepID=UPI000BE5B8A1 +---------LQEERLGARIGIAVVDTASGETV-SYRGDERFPLNSTHKALLCGALLSKVD +KGELALNETTQFAQSELVTWSPVTSKFVAPAMSWQQLCSAAITQSDNTAANLLAKKLGGP +AAVTRFFADSGDSVTRLDRGEPELNSAVPGDLRDTTTPLAVSHTLQKLALGELLTPRSRA +QLVQWMKEDKVADALLRSTLPKGWVIGDKTGAGDYGSRSIISIVWPKKGAPRIVSIYITD +TKATMAQSNDAIARIGKAIFS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q5MD98_ECOLX +-----EQIKLSESQLSGRGGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAMLARVD +AGDQQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLVPNNKAERIVVIYLRD +TPASRAERNQQI----------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. LM7 TaxID=1938607 RepID=A0A1S6FJZ5_9SPHN +--AFREAVQAVEQASGGRLGLAVIDTASGERF-GWRADERFPMCSTFKFALAAAILKQVE +AGRERLDRRIPVLAGDIVANSPFCQSRVGGSASVGELCRETIIVSDNSAANLLLRTIGGP +AGFTRRLRAFGDPATRLDRWETEMSEAKRGDVRDTTQPQAMADLARRLVLGKALAPASRA +QLTAWMKDTRTSGKSLRAGLPAGWVVADKTGSGGYGTDNLVGVVWPAGRAPLVVASYITG +GTLAFEQRRPLHARVGQAIVA-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. campestris (strain B100) TaxID=509169 RepID=B0RPW9_XANCB +--MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP +PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPCDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAGRDAALKAVAEAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI0009C07049 +--MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP +PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPCDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAGRDAALKAVAEAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia flavorosea TaxID=53429 RepID=UPI0007A4BCE6 +---ATAAFADLETTHGARLGVFALDTGTGRSV-GHRMDERFPMASTFKGLACGGLLDRHR +LSSGFLDQVIRYPRHELVEYSPVTEQHVDTGMTVADLCHAAITVSDNTAGNQILKLLDGP +AGFTAFLRSLGDSASRLDRWETELNTAIPGDERDTTTPAALAADYQALVVGDRLPEPERE +QLRSWLVATTSGADRIRAGLPTDWTVGHKTGTPAYGSALDVAVAWPPGRAPLVIAVLSTK +SEQDAEPDGALLAAATRIAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. A134 TaxID=2681970 RepID=UPI0012EDC87B +----EEVFKELEDEFDARLGVYAIDTGSEQTV-AYRSDERFAYASTFKPLAAGAILQTNS +--IEDLEKVITYSEEDLVTYSPVTEKHADDGMKLEEIIEAAVRYSDNTAGNLMLEELGGP +NGLEEILRENGDETTEMDRMETELNEAAPGDTRDTSTPQALAESLQKYVLSDLLPEDKRE +LLIDWITGNETGDSLIRAGVPEGWEVGDKSGAGSYGTRNDIAVVWPPNKAPIVIAVLSSQ +DTADADYNDELIEKAAERVIE-- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. TaxID=1872122 RepID=A0A519LMF0_9BURK +--AWNDTLAGIERTAQGRLGVAMLDTGTGLAL-GWRQDERFAMASTFKAVLAGWMLALVD +QGKERLDARVHYAAADVVAYSPASGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDGITRLDRTEPTLNEARVGDPRDTTTPLAMLQTLQKLVLGDVLTPASRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTTNSGTSNDIAVMWPPGGAPVVVTCYITA +STASSEQRDAAIAQVARAVVA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=A0A3Q9KC73_9ACTN +--RAAKALAQVERRYHSRLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAAALLKRST +--DDELNRVISYRASDLEDYAPITKRHVGKGMTLRDLIKAAVQYSDNTAANLLLDQLGGP +VGLQKALRDMGDRTTRTDRTEPALNEAKPGDPRDTSTPRALGTDLRRFVLGDVLPEGRRQ +LLTNVLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPTSGSPIVVAVLSDR +GSKDAASDDALIKDATKT----- +>[subseq from] Class A beta-lactamase n=1 Tax=Betaproteobacteria bacterium HGW-Betaproteobacteria-16 TaxID=2013707 RepID=A0A2N2TPH7_9PROT +---FHEQIAALEVAARCRLGVYIIDTATGREY-GHRPDERFMMLSSFKLLASALVLARAE +QGQDSLQRRIRYTREDLVTWSPVTEKHVGGELTLAQLCEATITTSDNTAANLILASYGGP +AAVTAFARKLGDTVTRLDRTEPELNRPSGAAPLDTTTPRAMTRTLQTLLIGNALAASSRH +TLLQWLKANTTGDKRLRAGAPADWAIGEKTGTNRT-DANDIGIAWPPGRAPLLVSAYLAE +STAPAAARDAALAGVGRLMA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces lunaelactis TaxID=1535768 RepID=A0A2R4TCC4_9ACTN +--EITGQLRGLEQEHSARLGVYARNTATGRTV-LYRADERFPMCSVFKTLAAAAVLRDLD +RGGEFLAKRIRYTAEDVKDYAPITGNHLAGGMTVGELCAATICYSDNAAANLLLRELGGP +TAITRFCRSIGDRTTRLDRWEPELNSAESWRASDTTSPRAIGQSYARLTLGTVLAPQDRE +RLTGWLLANTTSGERFRAGLPAHWPVADKTGGGKYGTNNDVGITWTPDRSPIVLAVLTTQ +QEPEALADNPLIAKTATLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus sojae TaxID=582851 RepID=A0A511ZFC6_9BACI +----EEVFKELEDEFDARLGVYAIDTGSEQTV-AYRSDERFAYASTFKPLAAGAILQTNS +--IEDLEKVITYSEEDLVTYSPVTEKHADDGMKLEEIIEAAVRYSDNTAGNLMLEELGGP +NGLEEILRENGDETTEMDRMETELNEAAPGDTRDTSTPQALAESLQKYVLSDLLPEDKRE +LLIDWITGNETGDSLIRAGVPEGWEVGDKSGAGNYGTRNDIAVVWPPNKAPIVIAVLSSQ +DTADADYNDELIEKAAERVIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=UPI0013E36FB9 +--RAAKALAQVERRYHSRLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAAALLKRST +--DDELNRVISYRASDLEDYAPITKRHVGKGMTLRDLIKAAVQYSDNTAANLLLDQLGGP +VGLQKALRDMGDRTTRTDRTEPALNEAKPGDPRDTSTPRALGTDLRRFVLGDVLPEGRRQ +LLTNVLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPTSGSPIVVAVLSDR +GSKDAASDDALIKDATKT----- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus polymyxa TaxID=1406 RepID=UPI0010BE3446 +-----VVFKQLEIKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS +--NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP +EGFEKAMRDNGDTVVMANRYETELNEAIPGDHRDTSTPNALANSLKVLTIDDSMPNDKQE +LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAVVWPPDRDPIIIAVMSSR +DTEDAEYNNALIAEAAKAAFK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces spongiicola TaxID=1690221 RepID=A0A2S1YWW7_9ACTN +----SRRLAELERTYSARLGVFARDTRTGRTV-SHRADELFPMCSVFKAPAVAAVLRDLD +RRGEFLAKRIHYTEKDTEEYAVITGRNLANGMTVAGLCDAAVRYSDNAAANLLLRELGGP +SAVTRFCRSIGDGVTRLDRWEPRLNSAEPWRVEDTTSPRGIAGTYSRLVLGDALSRPDRQ +RLTGWLLNNTTGTERLRAGLPDDWTLADKTGAGEYGTNNDVGIAWTPDGSPVVLAVLTTR +RHPDAAPDNRLVARIAELLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. H3C3 TaxID=2530368 RepID=A0A4R5BX89_9ACTN +--AVAKQLRGLEKTRRLRVGAYAIDTGNGQAL-SYRPDERFPFASTSKAPLCGAVLRKAR +TDPGLMDRVIRYTKDDLVPNSPVTEKRVDTGMTPAELCDAAVTVSDNTAANVLLKQIGGP +AGQTSFFRSLGDRASRQDRWEPDLNHWRPGERRDTTTPRAWAGDLRSLALGNALAPADRA +RLVGWMKDCETGGKRIRAGLPKDWTVGDKTGTGGYGSANDIAVAWPPSGAPLVIVIMTNR +PTPDGAADEEAIARTTTVLV--- +>[subseq from] Beta-lactamase n=1 Tax=Gandjariella thermophila TaxID=1931992 RepID=A0A4D4JAA5_9PSEU +--AAEAELSRLEATFGGRLGICAVDTGSGASV-RHRAGERFLMCSTFKALAVSAILRRRQ +QQPGLLDTVIRYDRSQLLPYAPVTSQHVAEGMTVSALCQAAITYSDNTAANLLLQVLGGP +PAVTAFARTLGDQLTRLDRTEPDLNVTAAGDQRDTSTPAQMAADLRVLALGDGLDPAGRD +LLVGWLKANTTGGRSIRAGLPAGWQVGDKTGSGAQGETNDIAVVWPPNHAPLVIAVYTAP +ADPKSTAGYATVARAATIVAN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudolabrys sp. GY_H TaxID=2292256 RepID=A0A371B0H6_9RHIZ +----AQRVAALEKKIGGRVGVYLRDITGRVLV-AHRADERFPMCSTFKFLLAAAALRRVD +QGQMSLDQVLNFGEADLLSYAPVAKANVAKGLSLGELCAAIVTVSDNTAANVILRNIGGP +QAVTAFARAIGDPDTRLDRTEPELNSAIPGDPRDTTTPQAITEDLFRLLSGNVLAPASQQ +MLENWMIASKTGLKRLRAGVPNGWSVGDKTGTGANGSANVVAIIRPGNRATLFASVYLTG +STAEADELDAVHAEIGRIAAD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Acidipila dinghuensis TaxID=1560006 RepID=A0A4Q1S8C7_9BACT +--AFEQRLKVIEAGTGGRLGVGFLDPANGIRA-GWKQDERFPMCSTFKVLAVSALLSRAD +RGEEHLDRLIRYGKADVVSYSPESSRHVDTGMTVSDICRAAMTLSDNTAANLILASIGGP +AGVTAFARSLGDEVTRLDRTETSLNEAVPGDPRDTTAPGEMVSDLRKVVTGNVLSAASRA +QLVAWMEANTTGKARIRAGLAASWRIGDKTGTGDHATANDIAVLWPEGRSPVFLCVYLTE +AQVKFPDQEAAIAAVAQAAA--- +>[subseq from] Beta-lactamase n=1 Tax=Catellatospora citrea TaxID=53366 RepID=A0A419XCH6_9ACTN +----VAAFAELETRFDARLGVYAIDTGTGRTV-EHRADERFAYASTYKALAAAAVLDTTT +--AEQLDRVVHYTAADLVTYSPVTDKRVQTGMSLREIADAAVRYSDNTAGNLLLDHLGGP +DGFERSLRGIGDRTTDAARHETELNQAAPGDTRDTSTPRALATDLRAYALGDGLADDDRT +VLNDWLRGNTTGAKLIRAGVPTGWQVGDKTGAAAYGTRNDIAVVWPTDGAPIVLAILSSH +DEQDATYDDALIAQAAAAAVT-- +>[subseq from] Beta-lactamase n=1 Tax=Blastococcus xanthinilyticus TaxID=1564164 RepID=A0A5S5CV35_9ACTN +---VSADLAQLEAEFGARLGVFAVDTGTGRTV-AHRADERFAFASTHKALSAAAVLDRTS +--PAELDELVPYAAADLVAHSPVTGQHAGAGLPLRDLLAAAVGQSDNTAANLLLARLGGP +VGLERALRELGDDVTRADRTETELNEAVPGDERDTSTPRALAADLRAFLLDGALEPADRD +LLTGWMRDTVTGATLIEAGVPAGWDVAAKSGAGGYGTRNDIAVVWPPDGAPIVLAVLSSR +DTADAEHDDALVARAAAAVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF00832 +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLIKNS +--LEALDQKIRYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMRDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. 364 TaxID=2691571 RepID=UPI001318DC0C +----ARDFAALEAASGGRLGVTLLDTGSGRRF-GHRQDERFPMCSTFKFALCATVLQLAD +QGKLSLDRRLAMTTQDLLSHAPVTARHVGKDLTVRDLCRATLVTSDNPAANLLLRVVGGP +AGVTAFLRASGDDVTRNDRDEPEVNRFAPGDPRDTTSPAAMAASLQRLVLGEVLLPASRQ +QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ARVDDAARNDVLRQVAIIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CNZ306 TaxID=2035248 RepID=A0A2M9AMG4_9ACTN +-----RELAALEREYDARLGVYAVDTGSGREV-AYRAGERFPYASTFKALAAGVVLRTHS +--DRELDEVVTYSADDLIAHSPVTGEHVATGMTLRDLCEAAVRYSDNAAANLVLAELGGP +AGMDAELEDLGDDVTRMVRDEPELSRWDPDDTRDTSTPRALAEDLRALVLDDALDRRDRA +RLTEWLRTNTTGDTLIRAGVPETWRVGDKTGTGSYGARNDIAVLWPPDRAPIVLAVMTNR +TQRDAEPDDALLADAASAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0004BDD382 +----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLDKYS +--LDGLDRRVTYTRKELVANSPVTEKHVGTGMTLKELCDASVRYSDNTAANLLFDHVGGP +RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLGEALPAPERE +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR +ATKDAEPSDELIAEAASVVAD-- +>[subseq from] Class A beta-lactamase n=1 Tax=SAR86 cluster bacterium TaxID=2030880 RepID=A0A2A4XI21_9GAMM +-------AMEVERRLGARLGLAILDDESGRRW-TYQADQRFPMCSTFKVLASSAFLARVD +RGEDSLDRRVIISEDDLVSYSPLTETRVAGQMTMAEICEAALTLSDNTAGNKILESIGGP +SGLTEFARSIGDAVSRLDRWETELNEALVGDERDTTSPHAMTQTLRELLLGDTLTENSRQ +QLAHWMTANKTGDSKLRAGLPLEWTIGDKTGGGNNGTMADVAIVWPVNRPPLIVAVYMTE +TTASFDDCNAGIAEIASAL---- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. LMG 12462 TaxID=1591134 RepID=UPI0012650068 +--TLPQRLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD +RGELALERRVPVRKADLLANAPVSERHVGATLNVVELCRAAMIYSDNTAANLLLPLVGDP +PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPRDTTTPAAMAATMRALLLGDVLQPVSRQ +RLIAWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG +ATVDSAARDATLKAVAQAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI000F6D8695 +----NDALATIERSAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD +QGRERLDARVHYAAADVVAYSPVSGPRAGNALTVGELCSATVSLSDNTAANVLMARHGGP +AGFTAFVRSLGDPITRLDRTEPTLNEAAVGDPRDTTTPLAMLQTLQKLVLGDVLSPPSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTSDSGTANDIGVLWPPGGAPVLVTCYLTR +STASAEQRDAAIAQVARAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-4489 TaxID=1609095 RepID=A0A0X3V2E1_9ACTN +--AVTAQFTSLERKYGARLGVHAVATGTGATI-SYRADERFAFCSTFKALAAAAVLHHNP +--LSHLDQRITYTARDINSISPITQHHIATGMTLRELCDAAIRYSDGTAGNLLLRDLGGP +SQLTAYLRDLGDRTSRLDRYEPELNRDRPEDPRDTTTPRALAADYQRLLLGDALPPAKHA +LLKDWLVRNATGGRRIRAGLPPGWTVADKTGTGDYGRANDVAIIWPPHMAPLVIALQSDR +PGYSTPPQDALLAETTTHLV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI0012DA6A95 +----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +NGFEKSLKQIGDHVTKSNRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIVWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFB8316 +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPARWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAEYDDKLIADATKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus indicus TaxID=246786 RepID=UPI000493465F +--AHHHDFAELEERYDAKLGVFALDTGTNQTV-SYHPDERFAYASTHKALAVGVLLQQKS +--LEDLNQRIAYTSEDLVNYNPITEKYIDTGMTLKELADASLRYSDNTAGNLILKQLDGP +AGFKKALEDIGDNTTSPERFEPDLNEVNPGETHDTSTPRALAASLQAFILGDALPPEKRE +LLIDWMKRNTTGDALIRAGVPEGWEVADKTGAASYGTRNDIAIIWPSKGDPIVLAVLSSR +DKKDAEYNDKLIAEATEKAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Terribacillus saccharophilus TaxID=361277 RepID=UPI000BA70634 +-----ASFSSLEETYDARLGVFAIDTGSGRTV-AYRENERFGFASTHKALSVGVLLQQKS +--MEDLNKRIMFTGDDLVNYNPITEKHVDSGMTLKELSEASISYSDNTAANLIFEEIGGP +DGFEDGLRKIGDQVTNSERIEPDLNNTQPGDTRDTSTPKAMAESLREYALGDHLSADKRQ +LLIDWLKGNTTGDALIRAGVPKDWEVGDKTGAGSYGTRNDIAILWPPDEEPIVLAIMSDH +DEADANANDDLIAEAAEAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Terribacillus saccharophilus TaxID=361277 RepID=UPI000BA6F032 +-----ASFSSLEETYDARLGVFAIDTGSGRTV-AYRENERFGFASTHKALSVGVLLQQKS +--MEDLNKRIMFTGDDLVNYNPITEKHVDSGMTLKELSEASISYSDNTAANLIFEEIGGP +DGFEDGLRKIGDQVTNSERIEPDLNNTQPGDTRDTSTPKAMAESLREYALGDHLSADKRQ +LLIDWLKGNTTGDALIRAGVPKDWEVGDKTGAGSYGTRNDIAILWPPDEEPIVLAIMSDH +DEADANANDDLIAEAAEAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces libani TaxID=68043 RepID=UPI001358CF6D +--RAAKALAQVERRYHSRLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAAVLLKRST +--DDELNRVINYRASDLEDYAPITKRHVGEGMTLRDLIKAAVQYSDNTAANLLLDRLGGP +AGLQKALRGMGDRTTRTDRTEPTLNEAKPGDPRDTSTPRALGTDLRRFVLGDVLPEGRRQ +LLTHVLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPAGGSPIVVAVLSDR +GSKDAASDDALIRDATKT----- +>[subseq from] Beta-lactamase n=1 Tax=Chromobacterium vaccinii TaxID=1108595 RepID=A0A2L2BGI8_9NEIS +---LKKAVQAEEKTLRARIGVAALDGGGGEAW-SYRGDERFPINSTFKAFACAALLAKVD +RKEAALEQTASIDQSMLAGWSPITEKRLAPQMTLDEVCQAAVSYSDNTAANVVLEAIGSP +AGFTAFMRRIGDEQTRLDRTEPDLNEGTPGDPRDTTTPNAVVASLRKVMLGDALSAASRE +KLGRWMREDRVADELLRSSLPAGWEIADKTGAGGYGSRNIIAVIWPPGRAPWLLGVYVTQ +TEASMPMRNQAIARIGAALTQ-- +>[subseq from] Beta-lactamase n=1 Tax=Glycomyces fuscus TaxID=1407559 RepID=A0A2A6F4W4_9ACTN +--ELAREFERLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYASTHKALSAGAVLQQNT +--LEEMEEVVTFTEDDLVDYSPITEQHVDTGMTLMEVADAAVRHSDNTAANLLLEELGGP +DGFEDALEEIGDDVTDPERIETELNAWTPGEEQDTSTPRAMAGSLREFTLGDALPEDRRE +VLNDMLVNNTTGDELIRAGVPEDWRVGDKTGSGSHGTRNDIAVIWPSEGDPIVLAVMSSR +EAEDAEYDNALIARAAEVVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Actinokineospora cianjurensis TaxID=585224 RepID=A0A421B0Y7_9PSEU +--ALVREFAQLEGKYDARLGVYAVDTGRGRAV-AYRADERFAYASTFKAFAAALVLDATT +--PQQLEESVPIRAADLVANSPVVERAVGGTMTWRELCDAAVRYSDNAAGNLLLRRIGGP +AGLKAGLAALGDQVTSADRYEPDLSSAIPGDPRDTSTPRAMATNLRQFAVGSALSEEDQM +LLNDWLRNNTTGKDVIRAGVPRDWTVGDKTGSADYGGRNDIAVLWPPGRDPIVIAVLTSR +DKEGAERSDALVADTARVVARVf +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID2955 TaxID=2690257 RepID=A0A6B1PH58_9ACTN +-------LAELEQRYGARLGVYARNVRTGRTL-AHRAGERFAMCSTFKAFAAAAVLRDRA +-GCAPLNRVVHYPPLDLLPNSPRTTEHQATGMTVADLCAAAIQYSDNAAGNLLLREIGGP +AGLTRFYRSLGDRTSRLDRWEPELNTAIPGDPRDTTTPEAVAASLEHVTLGRALAPAGRE +RLVGWLKGNTTSAARFRAGLPGEWTVADKTGTGSYATANDIGVAWTTRGTPVVLVVLSTR +PTPDAAVDEKLVEEAARVMA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A410ZH92_BACIU +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS +--IEKLNKVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E1F513E +---LRARWAEIQRGTGGRLGISLLNSVTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP +PGLTRFLRGIGDTKTRSDRLEPAMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWLPGRAPLLLTAYLNG +ATVDAAGRDAALKAVAEAVR--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A2A4BDE2_9BACI +---TIKKFEQLEKEYEAKLGVYAIDTGTKKTV-EFHENERFAFTSTHKALAVGALLQQKS +--IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP +AGFKKALEGIGDNVTNPERIEPDLNVVNPGETHDTSTPLALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAILWPAKGDPIVLAVLSSR +DEKEADYNDELIAEATEEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Catellatospora paridis TaxID=1617086 RepID=UPI0012D42DEA +--SATAAFADLETRFDARLGVYAVDTGTGRFV-EHRADERFAYASTYKALAAAAVLDATT +--AEELDRIVRYTAADLVTYSPVTEKNVQTGMTLRALADAAVRYSDNTAGNLLLDHLGGP +DGFERALRDIGDQTTDAARHETELNEATPGDNRDTSTPRVLATDLRAYALGGDLADDDRT +VLTDWLRGNTTGAKLIRAGVPAGWQVGDKTGAGSYGTRNDIAVVWPTDGAPIVLAVLSSR +SQQDAKYDDALIAQAAAAAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus polymyxa TaxID=1406 RepID=UPI00046F6DFF +-----VVFKQLEIKFDARLGVYVIDTETGKEV-AYRADERFAYASTYKALAAGAVLQQKS +--NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP +EGFEKAMRDNGDTVVMANRYETELNEAIPGDHRDTSTPNALANSLKVLTIDDSMPNDKQE +LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAVVWPPDRDPIIIAVMSSR +DTEDAEYNNALIAEAAKAAFK-- +>[subseq from] Beta-lactamase n=1 Tax=Terribacillus saccharophilus TaxID=361277 RepID=A0A268AFF1_9BACI +-----ASFSSLEETYNARLGVFAIDTGSGRTV-AYRENERFGFASTHKALSVGVLLQQKS +--MEDLNKRIMFTGDDLVNYNPITEKHVDSGMTLKELSEASISYSDNTAANLIFEEIGGP +DGFEDGLRKIGDQVTNSERIEPDLNNTQPGDTRDTSTPKAMAESLREYALGDHLSADKRQ +LLIDWLKGNTTGDALIRAGVPKDWEVGDKTGAGSYGTRNDIAILWPPDEEPIVLAIMSDH +DEADANANDDLIAEAAEAAV--- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces albulus TaxID=68570 RepID=Q769D6_STRA9 +------ELHELERKYGARLGIYAVNTGDGREV-GFNADERFAYASTFKAFAAAAVLRKYS +--LSGMDKVITYSRSDLIDHSPVTEKHVGTGMTLRDLCDAAVRYSDNTAANLLFDVLGGP +QGLAAALAGTGDTTTKVERREPELNQWSPGATQDTTTPRAWAGDLRAFALGDALGKDERE +QFTQWLRTNTTGDELIRAGVPKGWDVGDKTGGGGYAVRNDIAVVWPPGAAPIVMAIMSNR +ATKDADYDNKLIAEAASVVTK-- +>[subseq from] Beta-lactamase n=1 Tax=Bordetella hinzii TaxID=103855 RepID=A0A0H4W2P3_9BORD +--DAQRQLARLEAREGGRLGVSLLDVQSGYAI-AYRADERFALCSTFKLLAVGAVLTRVA +RGEDDLSRPMRLSAADIVDYSPVTQQRLNEGMTLGQLCEAALLWGDNTAANLLLSTIGGP +PGVTAYARALGDGATRLDRLETALNEARPGDERDTTTPAAMLGNLRQLVLGDALPAPERE +RLRDWLMQCRTGQQRLRAGLPAGWSLGHRTGAGGHGTCNDIGVAWPTPTTPVVISVYLTE +SPLDLPERERVLAEAARILAH-- +>[subseq from] Beta-lactamase n=1 Tax=Telmatospirillum siberiense TaxID=382514 RepID=A0A2N3PWJ4_9PROT +--SLDESLAELERVNGGRLGVAILDTGTGARV-GYRADERFPMCSTFKFLLVAAVLRRVD +RHRDALERAVGIPPKPLLFNSPLTEPHARRSMSVAALCHAALTRSDNTAANLLLASIGGP +SGVTRFARSIGDKVTRLDRQEPALNESLADDPRDTTSPMAMAGNLESVLLKGVLSPASRD +QLTAWMEQNQTGLDRLRAGLPQGWRVADKTGANGEHTSNDIAVFWPEGRPPLIAAAYITQ +CPGPESKRAAMLAEIGRLA---- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS094228 TaxID=2033515 RepID=A0A2H3LU28_9BACI +--ATIKKFEQLEKEYDAKLGVYAIDTGTKKNV-EFHENERFAFTSTHKALAVGALLHQKS +--IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP +AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWAVADKTGAGSYGTRNDIAVIWPSKGDPIVLAVLSSR +DEKEADYNDELIAEATEEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000BF06339 +------AFTALEKEYTARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRRYG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAGDLRAFVLGDALAKPERA +RLAQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +RDADADYDNTLIAKATSAAV--- +>[subseq from] Beta-lactamase n=1 Tax=Lysobacter alkalisoli TaxID=2591633 RepID=A0A514BQ77_9GAMM +-----AQLAALERRHGGQLGVAILDAHSGRRI-NHRGEERFALLSTFKFLAAALVLARVD +RGEERLERRVVFEREALVPYSPVTEGRTGGAMSLAELCHATVTISDNTAGNLLLESFGGP +PALTAFARTLGDRHTRLDRIEPELNIVPPGEERDTTTPAAMLTSMRALLIDETLSAASRQ +QLVDWLVATSTGDARLRAGFPQGWRVGNKTGTNGN-ASNDIAIAWPPGRAPLLVSAYYDN +GELPPEQRDAVLAEVGRIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520HBK1_9BURK +---TRRALRRIEAAAGARLGVGILDTASGQRV-GHRADERFPMCSTFKFLAAALVLRRVD +RDLESLDRPVAIRADRLVTYSPATGRHAGGHMTMGELCEAAVTLSDNSAANLMLESFDGP +AGLTRFARSLGDDVTRLDRIETTLNEATPGDPRDTTSPAAMLGLMRELLLGRALAPASRE +RLRSWLGANTTGATSLKAGLPADWRIGDKTGAGGHGTRNDIAIVWPRTGAPVLVTAYLTG +ATLDDAAQRRVLAEVGALL---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia violaceofusca TaxID=941182 RepID=UPI0007A5187A +-----TEFRDLEARLHGRLGVYALDTGTGRAV-EYRPDERFPYCSTFKALAAGALLSTLP +--PAELDRRVTYTRADLVPNSPVTEQHVDQGMTVREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRAVGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPSVAADDRD +VLTGLLRANTTGAALIRAGAPAGWQVGDKTGGGDYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDAEYDNAAIARAATIAI--- +>[subseq from] Beta-lactamase class A n=1 Tax=Quadrisphaera sp. DSM 44207 TaxID=1881057 RepID=A0A1H0Z1T4_9ACTN +--AAQAAFAQLEADHDARLGVYALDTGSGRSV-EHRADERFAHASTYKALAAAAVLERTS +--SADLERVVPVTDADLVTHSPIAEQRAGTGMTLREVADAAIRYSDNTAGNLLLRELGGP +DGFERSLRSLGDAVTDPERLETDLNEAVPGDVRDTSTPRALATDLHAYAVGDALPEDDRA +LLTGWLRENTTGDALVRAGAPAGWVVGDKTGAGGYGTRNDIAVLWPPSGDPVVLAVLSSR +DEPDADHDDALVADATRVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas oryzae pv. oryzicola TaxID=129394 RepID=A0A0C5V911_9XANT +--MLRAQWAEIECGTGGRLGINLFDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP +AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRT +QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Class A beta-lactamase n=1 Tax=Geomonas soli TaxID=2496871 RepID=A0A3N7HTC8_9BURK +-rEVQAQIADIERETGGQVGVFALDTHTGQHL-GHRAGERFAMCSTFKLPLAAAVFARVD +RAELSLEQSIAFSERDLVPHAPVAEKHLASGISLGECCDAMVLLSDNVAANLVLPLIGGP +AGFTRFMRTLGDPVTRLDRNEPGLNTNLLGDPRDTTTPQAMAHSLAALLTGEHLSAPSRE +RLVDLMRRCSTGLQRIRGGLPADWNAGDKTGTGSRGAVNDIAAAWPPGRRPVVISVFLSG +SALPASKLNESHTKIARIVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Microbacterium sp. SLBN-154 TaxID=1985300 RepID=A0A542MZ40_9MICO +---VTDELSSLEEQYDARVGVYAVDTGTGETV-AHRADERFAYASTFKALLAAVVLQQVD +----DLDQQVAYGADALVTYSPVTEQYAGSGMSVADLAEAAVRVSDNTAANLLLDQIGGP +EGLAAALTAAGDDTTRPERREPELNTAVPDDPRDTSTPRALAETLRGFALDGGLSEDDAA +TLIDWMSGNATGDTLIRAGAPSGWDVADKSGTGQYGTRNDLAIVWPPDGEPIVVAVLTTR +GVEGATTDDALVAAAAATALE-- +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillus sp. TCA20 TaxID=1499968 RepID=A0A069DK38_9BACL +---ADESYADLEEEYDTRVGVFAWDTGSGKTV-SYRADERFAYASTFKALAAGAILLKES +--EEELDKIIKYSKEDVEENSPITEKHVTTGMKLSEIMDAAIRFSDNTAGNLMLKELGGP +KGFETVLREIGDTVTMADRYETELNEAVPGDDRDTSTPRALANSLHHFILTDTLSEQERT +LLTHWLHSNTTGDELIRAGVPEGWNVGDKTGAGSYGTRNDIGIIWPPDRDPIVLAIMTSR +DEKDAEYDNSLIARTTELAVQ-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=C8CE51_ECOLX +---------------------------------SFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEICASLIKHw +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces regalis TaxID=68262 RepID=A0A117MK18_9ACTN +--DVTTRLRALEEQHGARLGVFAHNIATKQTV-RYRADERFPICSLFKTLAAAAVLRDLD +RDGEVLAKRIHYTADDLVENSKETEKHLATGMTVAELADVAIRFSDNTAGNLLLRELGGP +TAVTRFARSLGDPVTRLDRWETELNSAEPWRTTDTTSPRAIGRTYARLVLGNALNRPDRD +LLTHWLLNNTTSANRFRAGLPKSWTIADKTGGGFYGTNNDAGIAWTEDGTPLVLAVQTTK +PEQDAAPDHALIVETAALLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Quadrisphaera sp. DSM 44207 TaxID=1881057 RepID=UPI000B872772 +--AAQAAFAQLEADHDARLGVYALDTGSGRSV-EHRADERFAHASTYKALAAAAVLERTS +--SADLERVVPVTDADLVTHSPIAEQRAGTGMTLREVADAAIRYSDNTAGNLLLRELGGP +DGFERSLRSLGDAVTDPERLETDLNEAVPGDVRDTSTPRALATDLHAYAVGDALPEDDRA +LLTGWLRENTTGDALVRAGAPAGWVVGDKTGAGGYGTRNDIAVLWPPSGDPVVLAVLSSR +DEPDADHDDALVADATRVAL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces jumonjinensis TaxID=1945 RepID=A0A646KK50_STRJU +-----SQLAALERKHGARLGVYALATGTGATV-AYRADERFAFCSTFKTLAVAAVLHRNP +--LSRLSERVTFTQADVNSISPITRDHIGTGMTIGQLCDAAIRHSDGTAGNLLMRDIGGP +ARLTAYLRGLGDTVSRMDHYEPELNRVPPRDPRDTTTPRAIGGDYRRLVLDDALSADKRA +LLKDWLERNTTGDKRIRAGVPRAWTVADKTGTSRYGRANDIAVVWPPGQAPLVVAIMSDR +PGQDTPPKETLIAEATARIV--- +>[subseq from] Beta-lactamase n=1 Tax=Allokutzneria albata TaxID=211114 RepID=A0A1G9ZRY5_9PSEU +----DERLFELERKFDARLGVYAVATGTGRTI-AHRADERFAFCSTFKGLAAAAVLHHNP +--MSHLDTVVKYTKDDLLKNATITPRHLETGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +ARLTEYARGLGDTVTRMDRIEPAITEATPGDPRDTTSPRAFGATYQKIVLGDALPPEKRA +FLRDLLERNTTGAQRIRAGVPGGWTVADKTGTGDYGTLNDIGIVWPPNSPPIVIAIMSSK +AAKDAKYDQALIAEAAAHVA--- +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SVT1_9BACT +---MDEKFAKLENEFDARIGIFAVDTETNQTV-AYRPDERFAYTSTFKVLAAGILLKQND +--IQELEKVITYTKDDLVTYSPVTKKHVDTGMTLLEISEAAIRKSDNTAGNLLLETLGGP +EKFQNTLRKIGDDVTNAERYETELNEFKPGNTRDTSTPRAMAINLKKFALGDLLPDVKRK +LLNEWMQGNATGDPLIRAGAPEGWKVADKSGAGTYGTRNDIAVVRPPDREPIVIAVMTRH +DTEDAKFDDALVAKAAEITL--- +>[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. AU243 TaxID=1713224 RepID=UPI000D6880F6 +--ELMDTVTRLESEVGGRIGVVLQHTGSEWGI-EHREDERFPMASTFKALLCGAVLSRVD +RGEESLDDLVTYKATELVSYSPVTKNHVASGMSVGQLCEATVTMSDNTAANLLLKRVDGS +EGLTRFLRGLGDRVTRLDRNEPALNEAKHGDSRDTTTPSAVLKTLDRLLFEDVLLPSSRA +QLQQWMVDDKVADELIRKHLPKGWRIADKSGGGQNGSRGIISVIWPETGKPYLASVYMMG +SDASFRQRNAVIAAIGKAMIE-- +>[subseq from] Beta-lactamase TEM n=1 Tax=Labrenzia sp. OB1 TaxID=1561204 RepID=A0A161YYK8_9RHOB +---LASAVDDIAARLPARVGVAVIDTQSGTRW-SYRGDERFPSNSTFKAFLCAALLDAGA +RGVADPDRSVTIRRSDIVSYSPVTEKHIDGNFTIRDLCEITVTISDNTAANFVLKEIGGP +QAVTDYLRGIGDAVTRVDRMEPDSNTGIPGDDRDTTSPNAAAETLEKLVLEKTLPDDARR +ALTGWLMGNKVGDATLRAGLPDGWRIADKTGAGANGSRNNIAVIWPEGRKPVVIAVYITG +TTASLEARNSAIAEIGAALA--- +>[subseq from] class A beta-lactamase n=1 Tax=Actinokineospora cianjurensis TaxID=585224 RepID=UPI000EB36AE4 +--ALVREFAQLEGKYDARLGVYAVDTGRGRAV-AYRADERFAYASTFKAFAAALVLDATT +--PQQLEESVPIRAADLVANSPVVERAVGGTMTWRELCDAAVRYSDNAAGNLLLRRIGGP +AGLKAGLAALGDQVTSADRYEPDLSSAIPGDPRDTSTPRAMATNLRQFAVGSALSEEDQM +LLNDWLRNNTTGKDVIRAGVPRDWTVGDKTGSADYGGRNDIAVLWPPGRDPIVIAVLTSR +DKEGAERSDALVADTARVVARVf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. PTY087I2 TaxID=1819298 RepID=A0A1B9EXX2_9ACTN +------DFKELERKFDARLGVYAIDTGTGREV-AHNDRARFGYHSTFKALQAAVVLSTYS +--LDGMEKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +KGLDASLEKLGDDITRMDREEPELSGWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIRAGVPKGWVVGDKTGTGGYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPDDRLIAEAATVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID161 TaxID=2690251 RepID=UPI001370B1F5 +-------LAELEQRYGARLGVYARNVRTGRTL-AHRAGERFAMCSTFKAFAAAAVLRDRA +-GCAPLNRVVHYPPLDLLPNSPRTTEHQATGMTVADLCAAAIQYSDNAAGNLLLREIGGP +AGLTRFYRSLGDRTSRLDRWEPELNTAIPGDPRDTTTPEAVAASLEHVTLGRALAPAGRE +RLVGWLKGNTTSAARFRAGLPGEWTVADKTGTGSYATANDIGVAWTTRGTPVVLVVLSTR +PTPDAAVDEKLVEEAARVMA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0012B8026A +---SDREFAKLEEKYDANLGIYALDTGTNKMV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR +TEKDAEYHDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium shewense TaxID=1761772 RepID=A0A1C3XJV3_9BRAD +------ELETYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIAYGKPDLLDYAPVAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP +ATLTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALSPASRA +LLTDWMVNCKTGANRLRGGLPADWTIGDKTGNNGKDASGDIAVVWPKPGTPILIAAYTQG +GAPNAAQIEAAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A3D5JRI1_9GAMM +---TATDLAALEAASGGRLGVTLLDTASGARI-GHRQDERFPMCSTFKFVLCAAVLHQAD +SGRLSLDRRVPVRQQDLLAHAPVTGRHVGKDLSVRDLCRATLITSDNPAANLLLGVIGGP +PAVTGFLRAHGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRLLLGDVLSAPARQ +QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGQDTTNDIAILWPLGGAPWVLTSYLQG +ARVDDAGRNEVLRQVAVIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI00141B05FE +--MLRAQWADIERGTGGRLGISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLRRVD +EGKLTLAQPVKIRASDMLEHAPVTKRHVGGTLSVGELCRATMIHSDNPAANLLFPLVGDP +AGLTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMVSTLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG +AKVDAAARDAALKAVAVAVREW- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TRM66233 TaxID=2654677 RepID=UPI0012E9F75C +--TTADALRALEREFDARLGVYAIDTGTGREV-AYRDNERFAYASTFKALAAGAVLRQHS +--PNGMNQVIKYSRNDLVAHSPVTKKYVTTGMTLRELCDAAVRFSDNTAGNLLLDALGGP +KGLNSALRDLGDDVTRVERREPELNQWAPGATRDTSTPRALASDLRALVLGDALGETERT +QLARWLRTNTTGAELIRAGMPKGWVVGDKTGAAGYAVRNDIAVVWPADAAPIALAITSNR +GEEDADYDNMLIAEAASVVAR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Frateuria terrea TaxID=529704 RepID=A0A1H6VII2_9GAMM +---PAARLAALEKQHGGRLGVAILDTANGRRV-AYRGDERVLMCSTFKVLAVAAVLARVD +RGDEQLSRRIVFGRDTLLGHAPVTRLHTGAPMRLEDLCAAAITVSDNTAANLLLATLGGP +PAVTAFVLGLGDRVTRLDRTEPELNVTRPGDLRDTTTPHAAVDTLRQLLLGEALSATSRA +RLLGWMRGCLTGTDKLRAGLPDGWSAGDKTGSGAQGESNDVAILFPPARPPLLVTAYYTA +PAAEAQLRSAVLAEVGRIAA--- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000BA04A6A +--AVQQKLAALEKSSGGRLGVALIDTADNTQM-----------CSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces violaceoruber TaxID=1935 RepID=A0A1V0UKV0_STRVN +----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLGKYS +--LDGLDRRVTYTRKDLVANSPVTEKHVGTGMTLKELCDASVRYSDNTAANLLFDHVGGP +RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLGEALPAPERE +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR +ATKDAEPSDELIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudogulbenkiania ferrooxidans EGD-HP2 TaxID=1388764 RepID=U1BQ45_9NEIS +---LKKAVQAEEKTLRARIGVAALDGGGGEAW-SYRGDERFPINSTFKAFACAALLAKVD +RKEAALEQTASIDQSMLAGWSPITEKRLAPQMTLDEVCQAAVSYSDNTAANVVLEAIGSP +AGFTAFMRRIGDEQTRLDRTEPDLNEGTPGDPRDTTTPNAVVASLRKVMLGDALSAASRE +KLGRWMREDRVADELLRSSLPAGWEIADKTGAGGYGSRNIIAVIWPPGRAPWLLGVYVTQ +TEASMPMRNQAIARIGAALTQ-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. CC53 TaxID=1906740 RepID=A0A1S2K8W2_9ACTN +---TTGRLRELEREHGARLGVFAYDTGTHRMV-AYRQGERFPMCSLFKPLAAAAVLRDLD +RDGEFLARRIPYGVEDLEPWSPVTKDHVGAGLTVEELCDAAIRHSDNTAANLLLRELGGP +TAVTRFCRSAGDGVTRLDRWEPELNSAEPWRETDTTTPYAIARTYGRLVLGGLLERRDRE +RLTGWLLSNTTSTERFRKGLPADWVLGDKTGGGSYGTNNDAGVTWPPGRPPIVLAVLTTK +PEPAALPDNPLVAEAARIVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodanobacter sp. L36 TaxID=1747221 RepID=UPI00131E8C47 +----VARLAALERRHGGRLGVSILDTGTGRRV-SHRGDERVLMCSTFKVLAVAAVLARVD +RGIEQLDRRIVFGNDVVLSYAPVTSKHVGAPMSVAELCEATIELSDNTAANLLLSSMGGP +QAVTKFVRGLGDPVTRLDRIEPDLNVGHAGDLRDTTTPNAMLATLQKLLLGDRLSSASRA +QLAAWMRACRTGIDQLRSGIPADWTAGDKTGSGAGDETNDVAVLLPPNRAPVVVTAYYVA +PVADVATRHAVLAEVGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Fastidiosibacteraceae bacterium SYSU SYW-6 TaxID=2219059 RepID=UPI000E6526BE +--SIHNNFKALEKQYGGQLAISAIDTSNNHAV-DYHADKRMPMCSTFKLMLVAAVLKKSV +DDPMLLEKKIVYTQKDMVNYSPYTQKNLGKGMTISALCHAAM-LSDNTAANLLLKQLGGL +KKLNQFARSIGDMTFRLDRYEPYLNTAIPGDKRDTTTAKAMSQSLDKIVLGDVLPTMQRD +LLIKWMQTNTTGDKRIRAGVNKSWIVGDKTGTGDYGTTNDIGVIWPNKCKPIVISVFYTQ +AKQDAKAQDAVIQKATSVAVA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2Z4G2X4_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKD------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. AcH 505 TaxID=352211 RepID=A0A0C2AT65_9ACTN +----EGAFGGLEQEFDARLGVYALDTGSGRTV-THRPDERFVYASTCKALLAGAVLDRYS +--LRQLERLVRYDRDDLVSDSPVTEKHVGTGLTLRELCDAAIRYSDNTAANLLFRQLGGP +RGLQTALRGLGDNVTRCDRYEVALSDAVPGDVRDTSTPRALAGGLRAYVLGATLPPDRRA +VLTDWLKRNTTGATTIRAGAPDGWQVGDKTGTGGYGTRNDIAVLWPPAAAPVVLAVMSRR +DTKNAERDDALIARAAKIAL--- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. IMTB 2501 TaxID=1776340 RepID=A0A1R0MA61_9ACTN +----EAELADLERRHGARLGVYGRNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDHG +-DRAPLDAVIHYPPHDILPHSPRTEEHVDTGMTVADLCAAAIQYSDNAAGNLLLRQIGGP +AGLTRFFRSLGDGTSRLDRWEPELNTALPGDRRDTTTPEALGRSFERLTLGRALARADRA +QLVTWLKGNTTSAARFGAGLPRDWVLADKTGTGDYGTTNDIGVAWTTRGTPVLLTVLSAK +VVQNAAADDGLVAEAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillaceae TaxID=186817 RepID=UPI000479286E +--DLDEAFTEIEEAFDARLGVYAIDTGTNQSV-EYNPDERFAYSSTYKLLAAAFVLKQND +--LQDLEEVVTYSKDDLVTYSPVTEKQVDTGMTLSEISEAAIRESDNTAGNLLLDALGGP +DNYKQALRDIGDDVTQPERYETELNAFSPENKRDTSTPRAMANNLRKVALGDFLPKEKQE +LLIDWIKGNATGDALIRAGKPEGWTVGDKSGAGSYGTRNDIAIVWPPGREPIVMAIMSRH +KTEGAEYDDELVAKAAEATLNAf +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. CFBP 7912 TaxID=1891621 RepID=UPI000CEEABD5 +--MLRAQWADIERGTGGRLGISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLRRVD +QGKLTLAQPVKIRASDMLEHAPVTKRHVGGTLSVGELCRATMIHSDNPAANLLFPLVGDP +AGLTTFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG +AKVDAAARDAALKAVAVAVREW- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces niveus NCIMB 11891 TaxID=1352941 RepID=V6JJL3_STRNV +---IKRAFADLERKFDARLGVYAIDTGSGRSI-THRPDERFAFASTCKALLAAVMLEKNS +--LRQLDRLVRYDRDDLAGYSPITEKHLDTGLTLRELCDATVRYSDNGAANLLFHEIGGP +KKLEAALVSIGDRVTRCDRYEDALSEALPGDLRDTSTPRALATDLRTYVLGDRLPADKRD +VLTDWLKRNTTGDKVIRAGAPAGWVVGDKTGTGGYGTRNDIAIVWPPKAAPIAIAVMSRR +DEKDAEPDDALLAGAAKVTLDAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Proteus vulgaris TaxID=585 RepID=G8A3S3_PROVU +---------------------------------SFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRILYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A4U0M9K3_BACME +---SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKGAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001117079B +---------------------------------LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis keratiniphila subsp. keratiniphila TaxID=227715 RepID=A0A1W2LMD6_9PSEU +--QFHDRLMELEKKYDARLGVYALDTGDGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVRYSRADLMKHAPVTERHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +AALTAFTRGLGDTVTRMDRIEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLAADKRD +FLRDLLQRTVTGAGRIRAGLPPGWTIAGKTGTGEYGTLNDIAVLWPPGKAPIVLAVMSSK +AAKDAPYDEALLAEAAKYVVE-- +>[subseq from] Beta-lactamase n=1 Tax=alpha proteobacterium AAP38 TaxID=1523418 RepID=A0A0N0K9L2_9PROT +---MREAMAALERARGGRLGVALLDTKTGAAM-NWRGDERFAMCSTFKFLLAGYILSRVD +AGQERLDRMVTFGKHELVTWSPLTEPHVDKGMSINDLCQAIMIQSDNTGANVLMRESGGP +TALTAFLRAAGDGVTRVDRIEPAMNVVGPDDVRDTTTPVSMLGLMRSLLLGEVLTPASRQ +RLTDWMIDNRTGKERLRAGLPAGWRIGDKTGTYD-AFNNDIAILWPPAGGPLLLTSYYAN +PTADKAVRNIVHAEVAAIVAKAy +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces antimycoticus TaxID=68175 RepID=UPI0010C4ABC7 +------AFKKLERSYDARLGVYAIDTGTGHEV-AYRDGERFGYASTFKALEAGAVLQKVK +--LGGLDRVIMYSKDDLIDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGP +KGLDAMLEKMGDDVIQMERREPELSRWVPGSTRDTSTPRAMAKDLRAFVLGDVLGDGERT +QLTKWLRTNTTGDALIRAGVPKDWQVGDKTGSGSYGGRNDIAVVWPPDSAPIVMAIMSNR +GDKDATSDDKLIADAAHVVADQ- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia niigatensis TaxID=209249 RepID=UPI00031D0453 +-----AALRALEQQHGARAGVVAIDTGTGKTV-GYRQDERFAFDSTFKPLACGALLHAHP +LGSGFFDQVIHFTPDKLVANSPITSTRVDTGMTVAELCQAAITHSDNTAGNQILELLGGP +PAVTAFLRSIGDQTTRMDRWETELNTNIPGDERDTSTPAALADDYRKLVLGDALAEPERT +QLTAWLLANTTGDARIRAALPADWKTADKTGSGDYGTANDIAVIWPAGGAPLVILVLTTK +PDQAAAADNPLVAALAKEAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Novispirillum itersonii TaxID=189 RepID=UPI0012DEDF3E +-----TKAAEIERTLGARVGVAVIDTASGQIW-EYRGNERFPLNSTFKALACGTLLQMAQ +RQELDLSQSVPVEAGAIVSYSPVTEKRVGSAMTLSDLCAATMTYSDNTAANLVLRAVGGP +VALTEALRRIGDPVTRIDRWEPDMNEATPGDLRDTTTPLAMARTLQSLALGTVLPGESGD +LFRQWLKDNQVSGPLLRAGLPGGWTVGDRTGAGGHGSRSVVAVVWPPQRKPLVVTAYLTQ +TKASMDQRNAALASLGREVAK-- +>[subseq from] Beta-lactamase n=1 Tax=Roseomonas cervicalis ATCC 49957 TaxID=525371 RepID=D5RSM8_9PROT +--EFARRMAEIEARSGGRLGVALLDTGSGFRA-GHRAAERFPMASTFKLLLAGAVLRRVD +EGKERLDRVIRFTRDDLVPYAPVTGPAAGGPLTVAALCEATVTLSDNPAANLLLDTVGGP +AGLTAFLRGLGDATTRLDRTEPALNEGRPGDPRDTTTPDSMAFLIRALALGDALRPASRE +RLMGWLLGNRTGDAQIRAGLPQGWRAAEKTGSNSAGIANDVGLLLPPGRAPVLLAAYLTE +ARIAAAERPALLAEVARAAVR-- +>[subseq from] Beta-lactamase n=2 Tax=Zoogloea ramigera TaxID=350 RepID=A0A4Y4CNX8_ZOORA +---ILAQMQTLEAEARGRLGVHVLDTADGATY-GYRADERFQTLSSFKFLASALVLHRVD +RGLESLDRRIPITPADIIPWSPVTERHVGDPMSLAALCEATITTSDNAAANLILDSYGGP +AALTAYLRTLGDSVTRIDRREPELNVKHPDEPMDTTTPRAMVMNLHKLVLGDALSAASRA +LLTKWLEGNTTGGKRLRAGLPDTWRVGEKTGTFQS-DANDSGVVWPPERAPLIVSAYLAD +SAVDSAARDATLAEVGRVV---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces decoyicus TaxID=249567 RepID=A0A0L8M3J6_9ACTN +--RAAKALAQVERRFHARLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAGVVLKRST +--DDELNRVIRYSASDLEDYAPITKRHVDQGMTLRDLVKAALQYSDNTAANLLLDQLGGP +AGLQKALRAMGDATTRVNRTEPTLNEAKPGDTRDTSTPRTLGTDLRGFVLGDVLPEGRRQ +LLTGWLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPASGAPVVVAVLSDR +GSKDAASDDALIKDATKA----- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces lonarensis TaxID=700599 RepID=UPI001438F73A +--SAASTFEQLEEEFDARLGVYALDTGTGEEV-EYRSDERFAFASTFKAFAAGALLAQYG +--LDGIDTTVAYDKADLISHSPVTERFTGEGMTLRDLAAAAVRQSDNTATNLLFDALGGP +TGLQAALRGIGDETTNVDRLETELNEATPGDDRDTSTPRAMAETLNAFVFGDVLDAQESD +QLVEWMTTNTTGATLIPAGVPDSWTVGDKSGAGGYGTRNDIAVLWPEEGEPIIMAVLSSR +DEEDATYDDALVARAATSA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ZL-24 TaxID=1933029 RepID=A0A2S3XXG8_9ACTN +---TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLSGAVLARKS +--LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP +RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGIRNDIAIVWPPGAAPIAIAVLSRR +DVKDAESDDALIAGAAKVALEAf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SPMA113 TaxID=913267 RepID=UPI00085305F9 +--AFTGEFKKLERAHDARLGVYAIDTGTGHEV-AYRDGERFAYASTFKALAAGAVLRKYS +--LSGLDRVIKYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDELGGP +RGLDTILEKMGDDVIQMEHYEPELSRWVPGATADTSTPRAMAEDLRAFVLGDVLDKGERS +QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGSGSYGARNDIAVVWPPDAAPIVMSIMSYR +GDKDADYDEKLIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF32C95 +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGL +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIADATKIALN-- +>[subseq from] Beta-lactamase CTX-M-2 n=1 Tax=Xenorhabdus doucetiae TaxID=351671 RepID=A0A068QVK4_9GAMM +--EIMHQLAMLEKNANGRLGAVLIDTSDHSTL-SYRANERFPLCSTSKLMAVSAILKQSE +TDAHLLHQRIHYQPSDLVEYSPITEKHLKEGMTLAELSAATLQYSDNTAMNLLLNQLNGP +DGVTTFARTIGDHDFRLDRQEPELNTVVPGDERDTSTPQAMANSLSHLALGNALATTQRE +QLVAWLKGNTTGSTSIRAGVPKDWIVGDKTGRCDYGTTNDIAVIWPPKRAPLVLVTYFTQ +PDKQAHARPDVLATAARIMTQNf +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia salmonicida TaxID=53431 RepID=UPI000A02D838 +----TATFADMETKYGARLGLSVVDTGSGATV-DYREGERFPMASTFKGLACGALLQAHP +LSTGYFDQVIRYTAADIVVNSPETEKHIDTGMTVTALCDAAITQSDNTAGNMLLRLLGGP +EGFTAFLRTLGDTVSRLDRWEPELNTAIPGDERDTTTAAALVANYRALVVGTALPEPERD +QLATWLKASKTGAKRIKAGLPTDWIVGDKTGSPAYGSALDVAIAWPPNRAPLVLAVLTTK +PDQNAEPSNDLVAEATKAAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus psychrosaccharolyticus TaxID=1407 RepID=UPI0002D71442 +--KPESKFAKLEEKYDAKLGVFAMDTGTNRTV-AYHPDERFAYTSTHKALAVGALLQQNS +--IEDLNQLIFYTREDLVNYNPITEKYVDTGMTLKELSDASLRYSDNTAGNLILNQIGGP +AGFKQALEEIGDTVTNPVRYEPDLNEVNPGETHDTSTARALAASLQAYTLGDTLSAEKRE +LLLDWMKRNTTGDALIRAGVPKGWVVADKTGAGLYGTRNDIAIIWPVKGDPIVLAVLSSR +DKKEAEYNDKLIAEATEAAIK-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium liaoningense TaxID=43992 RepID=A0A151FNV2_9BRAD +----PAELEAYERDTGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGKADLLEYAPVARQNLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSRPGDPRDTTTPAAMAGNLRRLVLGEALSTQSRL +QLTDWMVNCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVVWPKPDAPILIAAYTQG +GTPNAAQIATLFAQIGRMVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia niwae TaxID=626084 RepID=UPI0009FCB7D0 +-----ASFHEIETRHAARLGVYAVDTGSGRTV-VHREAERFPMASTFKGLACGALLRDHP +LSTGYFDQVIHYARSELVENSPVTEKRADTGMTVAELCDAAITVSDNTAGNQVLKLLGGP +EGFTAFLRSIGDTTSRLDRWETELNSAVPGDERDTTTPAALAADYRDVVLGDVLAEPERA +QLKSWLIASKTGADRIRAALPAAWTVGNKTGSPAYGSALDVAVVWPPGRSPFVIAVLSTK +AEQNAEADNPLVAEAARAAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces albulus TaxID=68570 RepID=A0A1A9QJB7_STRA9 +---ATGRLRALERRHGARLGAVARNTVTGATV-LYRSDERFPMCSTFKTLAAAAVLRDLD +RHGEVLAKRIRYTAADLVPNSKKCEENLATGMTVAELCDATIRFSDNTAANLLLRELGGP +AAVTRFCRSLGDTTTRLDRWEPELNTCEPWRVEDTTTPAALSGTYERLVLGDALNRGDRE +RLTGWLLGNTTSTHRFRAGLPEDWRLADKTGGGAYGTNNDAGVAWTPDGTPVVLVVLTTK +PEQEAAADDLLVARAASVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI00119D2AF7 +----NHHFAKLEEKFDAKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS +--IEELNQRITYTREDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP +TGFKKALEEIGDNVTNPERFEPDLNEVNPGETHDTSTPRALATSLQDFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWLVADKTGAGSYGTRNDISIIWPSKADPIVLAVLSSR +DKKDADYNDDLIAETTVEVM--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SLBN-192 TaxID=1119093 RepID=A0A542U454_9ACTN +---VTARLRELEQEHTARLGVYGRNLRTGRTV-AYRADERFPMASVFKTLAAAAVLRDLD +RDGEFLARRIHYTQEYVTKYSPITEDHVAIGMTVGELCDATIRFSDNTAGNLLLKELGGP +RAVTRFSRSVGDRITRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGSALEPRDRA +RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNNDVGITWPPDGPPIVMSVLTTQ +PEEDAPADNPLVAGAAALLA--- +>[subseq from] Beta-lactamase n=2 Tax=Acidovorax TaxID=12916 RepID=A0A2G6S8D5_9BURK +--AWNDALASIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD +QGKERLDARVHYPATDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDEVTRLDRTEPTLNEAAVGDPRDTTTPLAMLQTMQKLVLGNALSPMSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPQDGAPVLVTCYLTR +SKASPEQRDAAIAQVARAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. GPE 39 TaxID=1583099 RepID=UPI0005F2C9A0 +--ALQQRLAEIERRSGGRLGVYLLDSGTGQRI-GRREQERFPLCSTFKFLLVAAVLQRVD +RGEMGLDQRVRVRAVDVVSYAPVTKPHVGGTLSVDALCRAAMIFSDGGAANLLLRLVGDP +PGLTRFLRAHGDTQTRSDRNEPSMNGFALDDPRDTTTPAAMATTMRTLLLGDVLQPASRQ +RLIDWMIDNRTGDGCLRAGLPAGWKIGDKTGNNGSDSRNDIAIVWPPGRAPLLLTAYLNM +ATVDSDARDAALKAVAQAVVAWw +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium cajani TaxID=1928661 RepID=UPI0012F89EFB +------DLETYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGQADLLEYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDATSRLDHNEPELNRSRPGDARDTTTPAAMAGNLRRLVTGEALSAASRA +QLTEWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYVQG +GTPSTAQIAATFARIGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0012B72100 +---SDREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTARALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR +TEKDAEYHDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 04197 TaxID=2203199 RepID=A0A429DW79_9PSEU +--QFHDRLMELENKFDARLGVYALDTEGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVSYSRDDLMKHAPVTERHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +AALTAFTRGLGDTVTRMDRVEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTAEKRD +FLRDLLQRTVTGAGRIRAGLPPGWTIAGKTGTGEYGTLNDIAVLWPPGKAPIVLAVMSSK +SAKDAPYDEALLAEAAKYVVEE- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. QZS01 TaxID=2213226 RepID=A0A3Q9JHA7_9PSED +-----DKIKEIESQFNARVGYVQLDFSNGLLIdGYRYQERFPMMSTFKVLLCGAVLSRVD +SGLEQLNRRIRYRQSDLIEYSPVTKEHLSEGMTVAELCNATITMSDNTAANLLLSSIGGP +KELTKFLRKMGDPITRLDRWEPMLNESLPEDERDTTTPESMSKTLFTLLKGKTLTTNSRQ +QLIDWMEADKVGEPLLRSVLPKGWFIADKTGAGEHGSRGIIAILGPDEKPSRIVIIYLTG +SHTTMDERNKQIAEIGASLIKRw +>[subseq from] Beta-lactamase n=1 Tax=Hazenella coriacea TaxID=1179467 RepID=A0A4R3L7J1_9BACL +--TVTDDFAKLEEEFDARLGIFALDTGTKQTV-TYRADERFAYTSTHKALAVGALLQQKS +--ISDLNQRITYSQDDLVTYSPITEKYVNQGMTLKEICDASLRYSDNTAGNLILEQLGGP +SGFKKSLVAMGDDVTNPVRIEPELNDVKPGETHDTSTPRALATSLQAFTIGDTLPTEKRE +LLVDWMKRNTTGDALIRAGVPKGWEVADKTGGGFYGTRNDIAILWPPKGDPIVLAILSDR +DEKDAKFDDKLIAQATKEVID-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis azurea DSM 43854 TaxID=1238180 RepID=M2QLH9_9PSEU +--QYHDRLLELEKKFDARLGVYALDTGGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVSYSRDDLMKHAPVTGQHVATGMTIRQLCDAAIRFSDGTAGNLLLRDLGGP +GELTAFTRGLGDTVTRMDRIEPLITEATPGDPRDTTTPRAFGTDYQRILLGDTLASNKRD +FLRDLLQRNATGADRIRAGLPSGWTIADKTGTGDYGTLNDIAVVWPPGKPPIVMAVMSSK +AAKDAPYDQALLAEAAKYVVE-- +>[subseq from] Beta-lactamase (Penicillinase) n=1 Tax=Xenorhabdus bovienii str. Intermedium TaxID=1379677 RepID=A0A077QC52_XENBV +-nQITNQLSALEKNANGRLGVVLIDTADHSTI-TYRAHERFPLCSTSKMMTVSALLKKSE +TDEGLLNQRIHYQQSDIVEYSPITEKHLKDGMTLADLSAATIQYSDNAAMNLLIDQLGGT +HDVTRFARSIGDNAFRLDRKEPELNMVTPGDERDTTTPQAMANSLYKLALGNTLAATQRT +QLVEWLKGNTTGGASIRAGVPDNWIVGDKTGRCDYGSTNDIAVIWPDDKAPLILVTYFTQ +PNKDAEAHPDVLAAAARIMTQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5639 TaxID=1463867 RepID=UPI00055E7D05 +--KARRAFVRLERKFDARLGVYALDTGSRRSI-AHRADERFAYCSTCKAFLAGTVLKRNS +--LREMERRVRVRPQDLEGYSPIARKHVGSTMSLRELCDAAVRYSDNAAANLLFRELGGP +KGLQDALRDIGDRVTRADRYEVELSEGTPGDSRDTSTPRALATDLRAFVFGDVLPGRKRE +VLTDWLKRNTTGDKLIRAGAPSGWEVGDKTGNGGYGTRNDIAVLWPPKGDPVTLAVMSRR +DTRNAEHDDALIAEAAEVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces purpureus TaxID=1951 RepID=UPI0007C676C4 +--AITARLRRLERQHSARLGVFAHHTGTGRTV-AYRADEHFPICSVFKTLAAAAVLRDLD +HDGSFLARRIRYTAPYVTKWSPITGKNLAQGMTVAELCDATICHSDNTAANLLLTELGGP +TAITAFARSIGDRTTRLDRWEPELNSAEPWRETDVTTPGAIGLTYARLTLGNVLEPADRQ +RLTGWLLANTTSGERFRKGLPADWTVADKTGGGRYGGNNDVGIVWPPGQAPIVMAVFTTK +HKEDAPADNPLVAKTAALLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Cohaesibacter sp. ES.047 TaxID=1798205 RepID=A0A285M7T5_9RHIZ +---LKTTVSTWEGKLDARIGVILRDGSSDWEI-SYRADERFPMASTFKTLLCGAVLRRVD +DGQESLAELVTYSKKDLLSWAPITEKHVTGGMKLADLCEAAITMSDNTAANLLLSRVKGP +EGLTDFLCQIGDTTTRLDRWEPELNEATPLDPRDTTSPRAIATSLDKLLFGNALQPASAQ +HLKQWMIDDKVADKLIRPHVPNGWIIGDKTGAGGNGTRGIVAFIQTPEGQTYLAAIYITQ +TKAAFELRNQVISDIGKAIIS-- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura bangladeshensis TaxID=453573 RepID=A0A4R4P0N3_9ACTN +--EVTKQLTRLERTRHARIGAFAIDTGTGRTV-SHRADETFPFASTFKAMACGAVLRKAR +QAPGLLDKVIRYTEADLVDYSPVTEKHVGTGMTVADLCHAAITQSDNTAGNLVLRQIGGP +AGLTAFLRSLGDRVSRSDRWETALNDWRPGERRDTTAPRPWADDLRALTTGNALVPADRG +RLVGWLKATVTGDKRIRAGLPKSWTVGDKTGTGGYGTANDIAIAYPKAGAPLIIVITTNK +RTPDAEADDKAIARTAGILA--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. Huas11 TaxID=2183912 RepID=A0A495L9E9_9ACTN +--DAEADFALLEEEFDATLGVYALDTGSGEAV-EYRADERFGYASTFKVALFGALLEQTT +--PEEMEKVVTISEDDLVNWNPVTEERVGDDMSLLELGDAALRYSDNAATNLLLEELGGP +EALDAALEEIGDDVTSVDRIEPELNEGTPGDERDTSTPRAMATTLEAFTLGDVLPEEESD +LLVEMMRGNTTGDDLIRAGVPEDWEVGDRTGAGGYGIRNAIAVAWPPEGDPIVLAVMSSR +DQEDAEYDDALIAQAAEVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis dassonvillei TaxID=2014 RepID=A0A223QDT8_NOCDA +-----REFERLEEEFDARLGVYAVDTGSGEEV-EHRPDERFAYASTHKALTAALVLQQNT +--PEEMEEVVTYTEEDLVDYSPITEQHVDTGMTLMEVADAAVRHSDNTAANLLFEELGGP +DAFEDELEAIGDDVTDPERLETELNDWTPGDTSDTSTPRAMAGSLREFTLGDALPEDRRE +VLNNMLVNNTTGDELIRAGVPEDWRVGDKTGAGSHGTRNDIAVIWPPEGDPIVLAVMSSR +DEEDAEYDNALIARAAEVVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. 171095_106 TaxID=1286363 RepID=UPI00048E4865 +---SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKGAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BA599B1 +---SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKGAEYNDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNY243 TaxID=1169161 RepID=UPI000377C70A +-----RELAALEREYDARLGVYAVDTGSGREV-AYRAGERFPYASTFKALAAGVVLRTHS +--ARELDEVVTYSADDLIAHSPVTGEHVGTGMTLRDLCEAAVRYSDNAAANLVLAELGGP +AGMDAELEALGDDVTRMVRDEPELSRWHPDDTRDTSTPRALAGDLRALVLDDALGKRDRA +RLTEWLRTNTTGDTLIRAGVPGTWRVGDKTGTGSYGARNDIAVLWPPDRAPIVLAIMTNR +TQRDAEPDDALLADAASAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus TaxID=44249 RepID=UPI000737BBB2 +-----VVFKQLEVKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS +--NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP +EGFEKAMRDNGDTVVMANRYETELNEAIPGDHRDTSTPNALANSLKLLTIDDSMPNDKQE +LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR +DTKDAEYNNALIAGAAKAAFK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sviceus ATCC 29083 TaxID=463191 RepID=B5HXK1_9ACTN +--DITARLHALEERYDARLGVFAHHVTTGRSV-RHRADERFPMCSVFKALAAAAVLRDLD +RDGEVLARRIHYTEADLVQGSDQTAAHLAEGMTIAELADVAITFSDNTAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWEPELNTAEPWRRTDTTSPYAIGRTYGRLVLGDALDRRDRQ +LLTHWLLNNTTSVNRFHAGLPKTWTIADKTGGGSYGTNNDVGVVWTEDGDPIVLSVLSTM +PAQDAVRDDALVAEAAAVVAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNB091 TaxID=1169156 RepID=UPI0003812B2A +------AFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLREHG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAELGDGVTRMERRETELNEWTPGATRDTSTPRALAGDLRAFVLGDALGRPERA +RLTQWLTTNTTGGELIRAGVPEGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +ADADADYDNTLIAKAASAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. ERG5 TaxID=1381597 RepID=UPI0009E0A735 +--ELAAAVRACETASGGRLGVAILDIATAARF-SHRGDERFPMCSTVKLPLAAAILRAVD +QRRTRLDNRVPVSAGDILGHSPFSETRVGGTASLAELCEATLTLSDNAAANLLLPVIGGL +PGLTRFARTLGDTATRFDRNEPDLNEGKPGDPRDTTTPVAMLGLLNRMLLGSALSRAQRA +RLTRWMIGNHTGDNRLRAGLPAGWRVGDKTGTGGHGSNNDIAILWPPARAPLLVTSYLTG +SPLSSAASEAIHARLARSIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-2664 TaxID=1463842 RepID=UPI0004C4F5EE +------EFYELERKYGARLGVYAVNTGDGREV-AFNADERFAYASTFKAFAAAAVLRKYS +--LSGMDKVIKYSRSDLIDHSPVTEKHVETGMTLRDLCDAAVRYSDNAAANLLFDALGGP +QGLAAALAETGDTTTKVERREPELNQWSPGATQDTTTPRAWAADLRAFVLGDALGKDERE +QLTQWLRTNTTGDELIRAGVPKGWTVGDKTGGGGYAVRNDIAVVWPPGAAPIVMAIMSNR +GTKDADYDNKLVAEAASMVTK-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. NCIMB 12038 TaxID=933800 RepID=A0A1Y5LGP4_9NOCA +-qSLDAKIGALEAQYSTRIGVTAVDPATGAVY-SHRGDERFAMCSTFKAYASAAVLRRIE +DGSTSLDKTVVIEPGDLVENSPVTAAAAGTPMTLGQIAEAALTQSDNTAGNYLLREIGGP +QAITALARDVGDESTRLDRWETELNTAFRGDPRDTTTPAGLAQGFRALLLGDALDPASRD +QLLDWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWSPDGSPVVLAVLTDS +LTEDAQGNNQAIADTTAAVIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Arthrobacter sp. MA-N2 TaxID=1101188 RepID=UPI0004BC533A +----TEPFSGLEKEYDARLGVYGIDTGTGKTV-MHRADERFAYASTSKALLAGAILAKTS +--TPELDQIIRYTSGDLVSYSPVTEKHLDTGMPLREVIAAALQYSDNTAANLMFKQLGGP +KGLDESLKTIGDTTTHVDRTEPELNEAVPGDIRDTTTPKALGTDLAAYTLGNALTSEYRA +LLTGWLKGNTTGGNLIRAGVPSGWTVGDKTGGGSFGTRNDIAVIWPTTGAPIVLSIMSSK +STKDAKYDDALIAAATRAAIA-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SX83_9BACT +-----EAARQAEAQLDARVGLAVYDTGSGANW-LFNADESFPMGSTFKVLACGVLLARAD +AGDEDLDRFVEIVQTDLVTYSPVTETWVGRNVSLGEICAATMRTSDNTAANKVLEALGGP +GSLTAFLRSLGDQTTRLDRWETDLNEGTPGDPRDTTSPAAMAASFQKFVLGDVLSTSSRE +TLTDWLLGNEVGGPLLRAGLPEDWRIGDRTGAGGHGSRGIVAVLWPPGRAPLIAAIYLTE +TQATLEGRDAAIAAIGRAIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ADI98-10 TaxID=1522763 RepID=A0A3N6HY84_9ACTN +----GRAFSALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLREHG +--MGGLERVVRYRREDLVEHSPVTEKHVATGMSLGDLCDAAVRHSDNTAGNLLFDAVGGP +RKLQAVLAELGDDVTRMERRETELNEWSPGATRDTSTPRALAEDLRAFVLGDALGKPERA +RLTRWLRDNTTGGELIRAGVPQGWTVGDKTGAGSYGTRNDIAVVWPPGAAPLVLAVLSNR +EDADAAFDNTLIARATSAAV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces caeruleatus TaxID=661399 RepID=A0A117RHV9_9ACTN +haATTDRLRELESRHGARLGVFAHNLATGQTV-HHRADERFPICSLFKTLAAAAVLRDLD +RDGEVLGKRVYYTADDVVENSDITEDHVATGMTVAELADAAIRCSDNTAGNLLLRELGGP +CAITRFARSLGDPVTRLDRWEPELNSAEPWRRTDTTTPRAIGRTYARLVLGDALNRPDRD +LLVHWLLNNTTSVNRFRAALPETWALADKTGGGSYGTNNDAGIAWTDDGTPLVLVVQTTK +PEQDAAPDHALIVETAKLLTE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Xenorhabdus cabanillasii TaxID=351673 RepID=A0A3D9UJQ3_9GAMM +--QIINQLVALEKSANGHLGVFLINTADNSTI-GYRANERFPLCSTSKFMTASALLKKSE +KDGKLLNQRINYKQSDVVEYSPITEKHVESGMTLAELSAATLQYSDNTAMNLLLDQLDGP +RGLTKFARTIGDNEFRLDRKEPELNLVKPGDERDTSTPQAMAKSLYKLTLGNVLATNQRV +QLVEWLKGNTTGDASIRAGVPKDWVVGDKTGLCDYGSTNDIAVIWPTNRAPLVLVTYFTQ +PGKNAKARRDVLAEATRILTQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. BK215 TaxID=2512127 RepID=A0A4R3RTP4_9ACTN +---FAADFRRLEHTYGARLGVYAVDTGSGREV-AHNATERFAYASTIKAFAAVAVLRRHS +--PHGMEKVVRYAKGDLIAHSPVTEKHVGTGMTLRDLCDAAVRHSDNTAANLLFDAIGGP +KGLEAALREAGDTTTRVERREPELNQWAPASTRDTTTPRAFAADLRAFVLGDALGGPERA +QLTSWLRTNTTGDELIRAGVPKDWVVGDKTGGGGYGVRNDIAVLWPPGRAPVVMVIMSNR +GTEGAAYDNELIARAASVAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. LD22 TaxID=2650748 RepID=UPI00124E3E89 +--AVTKQLKALEKSRKDRIGAYAVDTGTGRFL-AYRADERFPFASTFKVMACGAVLRKAR +RDPGLMSRVIHYSKSDLVDYSPVTEKHVKTGMTVAALCKAAITQSDNTAGNLVLRQIGGP +AGDTAFLRSLGDRVSRHDRWETDLNIWRPGELRDTTTPRAWAGDLRALTAGGALVRADRD +RLIGWMKQTVTGDHRIRAGLPKGWTVGDKTGTGSYGAANDIAIAWPPSGAPVIIVITTNR +LTPDGTADEPAIAKTASILAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. BpilaLS-43 TaxID=1839778 RepID=UPI00081BC4C8 +---TAGAFEKLEDKYDARLGVYALDTGTGREV-THRADERFAYVSTFKALLAGAVLRTYT +--VGGTDRLITYSGDDVVPDSPVAEKHVDTGMTLDALCDAAVRYSDNTAANLLLRQLGGP +EALNALLKRLGDDVTRMERLEPDLSRWDPDSTRDTSTPRAFAENLRAFVLGDVLGDAERA +RLTHWLRTNTTGDEVIRAGVPKGWTVGDKTGTGGYGVRNDIAVLWPPDRAPVVVAVMTSR +DREDDTHDNRLLAEAASVVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF1615C +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLIKNS +--LEALDQKIRYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMRDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATQVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI00055F42B6 +--DITARLHALEERYDARLGVFAHHVTTGRSV-RHRADERFPMCSVFKALAAAAVLRDLD +RDGEVLARRIHYTEADLVQGSDQTAAHLAEGMTIAELADVAITFSDNTAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWEPELNTAEPWRRTDTTSPYAIGRTYGRLVLGDALDRRDRQ +LLTHWLLNNTTSVNRFHAGLPKTWTIADKTGGGSYGTNNDVGVVWTEDGDPIVLSVLSTM +PAQDAVRDDALVAEAAAVVAR-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. M7 TaxID=255705 RepID=A0A370VL80_9ACTN +--DVRARLRELERGHGARLGVYAHNVVTGRTL-THRADERFPVCSLFKPLAVAAVLRDLD +RDGEVLARRIHYTEADLVANSDVTRAHLETGMTVAELADAAIRFSDNTAGNLLLRQIGGP +TAVTRFARSIGDRVTRLDRWETELNSAEPWRVTDTTSPRAIGGSYARLVLGDALDARDRA +RLTHWLLHNTTSVNRFRAALPPPWTVADKTGGGSYGANNDAGVVWTEEGVPLVLAVMTTR +PEQDAAYDHALIVEATRLVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces mutomycini TaxID=284036 RepID=UPI000818AC91 +---TEGAFVELERKYGARLGVYALDTGSGRTV-THRSDERFAYASTCKVLLAGAVLDRNS +--LRRLDRLVRYSRDDLISNSPITERHVATGLTLRELCDAAVRYSDNAAANLLFRELGGP +RGLQDALRALGDDVTRCDRYEVALSDAVPGDLRDTSTPRALVDDLRAYVLGSALPADKRA +VLTDWLKRNTTGDHTIRAGTPDGWQVGDKTGTGGYGTRNDIAIAWPPGAAPIALAVLSRR +DAKNAESDDALLARAAEVAF--- +>[subseq from] Beta-lactamase n=1 Tax=Streptacidiphilus pinicola TaxID=2219663 RepID=A0A2X0IER5_9ACTN +-qAVEGRLRALERRHDARLGVFAYDTGTGRSV-RYRADELFPICSTVKTIAVAAVLRDLD +RDGRFLAKRIHYTAAYVTDYAPITGANVARGMTVAELCAAAIEYSDNGAGNLLVRELGGP +QAVTRFCRSVGDRVTRLDRWEPALNSAEPWRVTDTTSPRAVARTYARLVLGDVLTARKRE +LLTGWLLANTTSAHRFRAGLPKGWTVADKTGTGDYGTTNDVGFTWPPGRRPIVLSVLSTQ +HDATAPADEPLVADAAAAVVA-- +>[subseq from] Beta-lactamase n=2 Tax=Paenibacillus polymyxa TaxID=1406 RepID=E0RMI1_PAEP6 +-----VVFKQLETKFDARLGVYVIDTGTGKEV-TYRADERFAYASTYKALAAGAVLQQKS +--NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP +EGFEKAMRDNGDTVVMANRYETELNEAIPGDHRDTSTPNALANSFKVLTIDDSMPNDKQE +LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDRKPIIIAVMSSR +DTVDAEYNNALIAEAAKAAFK-- +>[subseq from] class A beta-lactamase n=1 Tax=Roseibium sp. RKSG952 TaxID=2529384 RepID=UPI0012BB5170 +-qHLQQTVTTWENRLDARIGVVLRDASSDWEI-SMRAKERFPMSSTFKSLLCGAVLARVD +AGQEDLSRRVTFSADDLVAYSPVTENHLQNGLTVGELCEATVALSDNTAGNLLLDTVGGP +EGLTAFLRYIGDQTTRLDRWETTLNEAVPGDPRDTSTPSAILTTLEALLLGDVLEPSSAA +QLRQWMIDDQVADALIRAHLPEGWVIGDKTGAGGNGSRAIIAFIEPKEDVHYFAAIYLTE +SDADFALRNQVVSEIGQAMI--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 04169 TaxID=2203197 RepID=A0A429DDR4_9PSEU +--QFHDRLLELEKKFDARLGVYALDTGGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVSYSRADLMKHAPVTERHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +AALTAFTRGLGDTVTRMDRIEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTADKRD +FLRDLLQRTVTGAGRIRAGLPPGWTVAGKTGTGEYGTLNDIAVLWPPGKAPIVLAVMSSK +AAKDAPYDEALLAEAARYVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. RJGP41 TaxID=2108534 RepID=A0A2T0CI37_9BACI +--EATIKFEQLEKEYDAKLGVYAIDTGTKKTV-EFHENERFAFTSTHKALAVGALLQQKS +--IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP +AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGGALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAVIWPSKGDPIVLAVLSSR +DEKEADYNDELIAEATEEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces prasinopilosus TaxID=67344 RepID=UPI0006EB29F4 +--RATAAFEELERTYGARLGVYAVDTGDGREV-THHDDERFAYASTVKAFAAAAVLREHS +--PSGMDEVITYSRDDLVAHSPVTGKHVDTGMTLRELCDAAVRHSDNTAANLLFDALGGP +KGLAAALAEAGDTVTRVERREPELNQWAPGATRDTTTPRAWADDLRAFVLGDELGGRERA +QLTKWLRTNTTGDALIRAGVPEGWVVGDKTGGGGYGVRNDIAVVWPPDAAPLVMAIMSNR +GTEDAGYDDKLIEEAASVVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI000BACC096 +--ATIKKFEQLEKEYDAKLGVYAIDTGTKKTV-EFHGNERFAFTSTHKALAVGALLHQKS +--IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP +AGFKKVLEGIGDNVTKPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEERE +LLIDWMKRNTTGDALIRAGVPKGWAVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +VEKEADYNDELIAEATEEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. MJM2582 TaxID=1427749 RepID=UPI0005080E66 +--QFHDRLMELENKFDARLGVYALDTGGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVSYSRDDLMKHAPVTERHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +AALTAFTRGLGDTVTRMDRVEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTAEKRD +FLRDLLQRTVTGAGRIRAGLPPGWTIAGKTGTGEYGTLNDIAVLWPPGKAPIVLAVMSSK +SAKDAPYDEALLAEAAKYVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000667D74D +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTARALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR +TEKDAEYHDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-1140 TaxID=1415549 RepID=A0A0N0TDR3_9ACTN +---VTARLRDLEREHTARLGVYARNMRTGRTV-VYRADERFPMASLFKTLAAAAVLRDLD +RDGEFLARRIHYTQADASQHSPVTKDHVATGMTVAELCDATIRFSDNTAGNLLLKELGGP +TAITRFARSTGDRVTRLDRWEPALNSAEPWRVTDTTSPRAIGLTYARLVLGDALEPRDRS +RLTDWLLRNTTSLERFRKGLPADWLLADKTGGGQYGSNNDVGITWPPDGPPIVMSVLTTQ +PEEDAPGDNPLVARTAALLA--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis rifamycinica TaxID=287986 RepID=A0A066TXP4_9PSEU +-----PDFAPLERGFDARLGVYAIDTGSGREI-AHRADERFGYASTHKAFSAAAVLQRTS +--REGLAKVLTYRRADLQQNSPVTEKHVGTGIPLRDAIDAALRYSDNTAANLLFDQLGGP +PGLAAALRAIGDTTTHVDRTEPALNDFAPGDIRDTSTPRAMAGTLRAFALGDALPPEKRT +LYTDMMRANTTGATVIRAGTPAGWAVADKTGTGDYATRNDIAVVWPPGRAPIVLAIMSSR +RAEDAGHDDRLLAQAAKLTFDAf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces chattanoogensis TaxID=66876 RepID=A0A0N0XSJ3_9ACTN +-----GEFKKLERKFDARLGVYAVDTGTGREV-AYNDGERFAHASTFKALAAGAVLSKYA +--PSGMGKVIKYSKSDLVENSPITEKHVETGMTLRELCDAAVRFSDNTAGNLLFDALGGP +KGLDAALARIGDDTTRMERREPELNRWAPGEQRDTSTPRALAKDLRAFVLGNLLGKGERA +QLTKWLRTNTTGGELIRAGMPKDWKVGDKTGAGSYGTRNDIAVVWRPHAAPIVVAILSNR +SKAGAHYDNKLIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces bohaiensis TaxID=1431344 RepID=UPI00143A3EE0 +--SAASTFEQLEEEFDARLGVYALDTGTGEEV-EYRSDERFAFASTFKAFAAGAVLAQYG +--LDGIDTVVSYEKADLVSHSPVTERFTTEGMTLRDLAAAAVRQSDNTATNLLFDALGGP +TGLQAALRGIGDETTNVNRTETELNEATPGDDRDTSTPRAMAETLNEYVFGDVLDAQESD +QLVEWMTTNTTGATLIPAGVPDSWTVGDKSGAGGYGTRNDIAVLWPEEGDPIIMAVLSSR +DEADATYDDALVARAATSA---- +>[subseq from] class A beta-lactamase n=1 Tax=Silvanigrella paludirubra TaxID=2499159 RepID=UPI001294F9BB +----QEKLLELEKSSDGRIGISAINTADNSKL-EYRAEERFAFCSTFKLMGVAAILKHSM +TNKNFLKEKINYKKDDIIAHSPITEKHLSDGMKIEELCKATITTSDNAAINLLIKKIGGL +NAVTSFARSIGDNNFRLDRYEIELNSAIPDDLQDTSTPSAMAKSIQKIVLGDVLALHQRE +LLQTWLKDSITGDAQIRSGVPKGWIVADKTGKGKYGTTNDIGVIWPPNCPPIVVAIYFTQ +KKQNAKYRDDVIASATNIIINAf +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillus ottowii TaxID=2315729 RepID=A0A544WKV8_9BACL +-----VVFKQLETKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQEKS +--NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP +EGFEKAMRDNGDTVVMANRYETELNEAIPGDLRDTSTPNALANSFKVLTIDDSMPNDKQE +LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR +DTEDAEYNNALIAEAAKAAFK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leucaenae TaxID=29450 RepID=UPI00040994C9 +--DADKQLADLEKRTGGRLGVSVLDTETNISL-GYREAERFALCSTYKALAVGFVLARVD +QGVEKLDRRVTYGKDAVVTYSPETEKHAGTDMTIAQLCGAAITLSDNTAGNLLLDSFGGP +AALTAWLRTTGDTETRLDRKEPDVNQAIKDDPRDTTTPDSMLDTIGLLTLGNTLSETSRD +QLSNWLVNNTTGNARLRAGLPKEWKVGDKTGTGQNGSYADVAVISPTDRGPILVTTYVGE +ATAPAKDVEAVFAEVGKIIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. RV163 TaxID=1661388 RepID=UPI00064C11FF +-----REFERLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYASTHKALTAALVLQQNT +--PEEMEEVVTFTEEDLVDYSPVTEQHVDTGMTLMEVADAAVRHSDNTAANLLFEELGGP +DAFEDELEEIGDDVTDPERIETELNDWTPGDTSDTSTPRAMAGSLREFTLGDALPEDRRE +VLNDMLVNNTTGDELIRAGVPEDWRVGDKTGAGSHGTRNDIAVIWPPEGDPIVLAVMSSR +EAEDAEYDNALIARAAEVVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Kitasatospora aureofaciens TaxID=1894 RepID=A0A1E7N7F3_KITAU +------AFKDLEQHFGARLGVYAVDTGSGREV-AYRSDERFAFASTIKSLLAGALLRTAS +--DQELDKVVTYRQDEVLTWAPITSRHVDTGMKVRDLAAAALEYSDNTAANLLMTELGGP +ENLQRTLRELGDPTTNVNRNEPTLNEATPGDPRDTSTPRAFAADLRRYVLGDVLTEDRRR +MLTDWMVGNTTGAPFIRAGVPAHWKIGDKTGNGGYGTRNDVAVAWPSGGSPVVLVVMSDR +GKADATSDDALIAEATKAVVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis trehalosi TaxID=109329 RepID=UPI000836B7F7 +----DAEFERLEEEYDARLGVYAYDTGSEETI-AFNADDRFAFNSTFKVLAVGALLQDRT +--LEDLEEVVHFTEEDLVNWSPITEQHVDTGMSLREVSDAAVRYSDNTAANLLFEELGGP +EGFEAALREIGDDVTNSDRIEPDLSSAVPGDDRDTSTPRAMATSLGEYTLGATLAADERE +FITDLLVRNTTGDALIRAGVPDDWKVGDKTGNGGYGSRNDIALLWPPEGDPILLAVMSSR +DQEDAEHDDALIADSAAVVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5917 TaxID=1463873 RepID=UPI000563CAA3 +--KARRAFVRLERKFDARLGVYALDTGSRRSI-AHRADERFAYCSTCKAFLAGTVLKRNS +--LREMERRVRVRPQDLEGYSPIARKHVGSTMSLRELCDAAVRYSDNAAANLLFRELGGP +KGLQDALRDIGDRVTRADRYEVELSEGTPGDSRDTSTPRALVTDLRAFVLGDVLPGRKRE +VLTDWLKRNTTGDKLIRAGAPRGWEVGDKTGNGGYGTRNDIAVLWPPKGDPIPLAIMSRR +DTRDAEHDDALIAEAAEVAF--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. W007 TaxID=1055352 RepID=H0BCD2_9ACTN +------AFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRRYG +--LRGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAELGDGVTRMERRETELNEWTPGATRDTSTPRALAENLRAFVLGDTLAKPERA +RLAQWLTTNTTGGELIRAGVPKGWIVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +TDADADYDNTLIAKATSAAV--- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. GC306 TaxID=2530367 RepID=A0A4R4SWZ0_9ACTN +--NVTEQISRLEKARDMRIGAYALDTGTGRAV-GHRADEAFPFASTFKAMACGAVLRKAR +NDPGLLDRVIRYKESDLSAHSPVTEKHVKTGMTVADLCHATITQSDNTAGNLVLKQIGGP +AGLTRFLRSLGDQVTRSDRWEPDLNDWRPGQKLDTTAPRPWAGDLRALTVGDALVPADRK +QLIGWLKATVTGDARIRAGLPHGWRAGNKTGTAGYGSANDIAIAWPPSGAPVIIAILTTK +RTPDAEPDEQAIARTTTILI--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. AY3-1 TaxID=2217817 RepID=UPI0011ECA357 +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN +FLIDLMKRNTTEDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIADATKIALN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus terrae TaxID=1914933 RepID=A0A429X2J3_9BACI +--NTDEKFAQLENEFDARIGVYAIDTGTNQTI-EYRPEERFAFASTYKALAAAILLQQNY +--LEDLMEVITYTEDDLVSYSPITEKHVDTGMTLLELSEAAVRFSDNTAGNLLFEALGGP +KGFEQALRQMGDNVTQADRFEPDLNEFTLGETRDTSTPRALATSLQAFGVSDLLSDDKRE +LFTNWLKGNATGDTLIRASAPEGWEVGDKSGAGGYGTRNDVAIVWSPNREPIVIAILSKK +NTEDAEYDDALIAQAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia fusca TaxID=941183 RepID=UPI0007A73EC8 +----TQQFADLETAHGARLGVFALDTADGRSV-AYRDGERFPMASTFKGLACGALLHKHP +LSSGFFDRVIQYPRTDLVENSPVTEQHVDTGMTVAALCEAAITVSDNTAGNQILKLLDGP +AGFTAFLRTLGDNTSRLDRWETELNTAIPGDERDTTTPAALAADYRALVVGDSLAEPERA +QLSAWLVASATGGNRIRAGLPAEWKVGNKTGSPAYGSALDVAVAWPPGRAPLVIAVLTTK +SEQDAKPDNALVAAAARAAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=alpha proteobacterium AAP38 TaxID=1523418 RepID=UPI0006B8E3A3 +---MREAMAALERARGGRLGVALLDTKTGAAM-NWRGDERFAMCSTFKFLLAGYILSRVD +AGQERLDRMVTFGKHELVTWSPLTEPHVDKGMSINDLCQAIMIQSDNTGANVLMRESGGP +TALTAFLRAAGDGVTRVDRIEPAMNVVGPDDVRDTTTPVSMLGLMRSLLLGEVLTPASRQ +RLTDWMIDNRTGKERLRAGLPAGWRIGDKTGTYD-AFNNDIAILWPPAGGPLLLTSYYAN +PTADKAVRNIVHAEVAAIVAKAy +>[subseq from] Beta-lactamase n=1 Tax=Lutibaculum baratangense AMV1 TaxID=631454 RepID=V4QXR4_9RHIZ +---VVEAAERLETELGGRIGVVLRE-QDGALVaTYRADERFPLGSTFKVLACGALLARVD +AGEDDLDRMIEYGREELVTYSPVTEKHAGQGMTLRDLCHATITLSDNTAGNLVLESIGGP +EGLTEFLRQAGDEVTRLDRWETELNEGRPGDPRDTTSPEAILATLERLLFGELLSPSSRR +QLEDWMIADQVADALIRSSLPDDWNIGDKTGAGGRGTRAIVAVIRPPESSPWLAAIYLTG +NEADLDTRNRVVAEIGAVMID-- +>[subseq from] Uncharacterized protein n=1 Tax=Xenorhabdus budapestensis TaxID=290110 RepID=A0A2D0J2X9_XENBU +--QIINQFIALEKSANGHLGVFLINTADNLTI-GYRANERFPLCSTSKFMVASALLKKSE +KDENLLNQRINYKQSDIVEYSPITEKHIASGMTLAELSAATLQYSDNTAMNLLLDQLDGP +RGLTKFARTIGDNKFRLDRKEPELNLVKPGDERDTSTPQAMAESLYKLTLGNVLATNQRV +QLAEWLKGNTTGDASIRAGVPKDWVVGDKTGLCDYGSTNDIAVIWPTNKAPLVLVTYFTQ +PDKNAKARRDVLAEATRILIQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI000750A3E0 +--KMQLELMTLEKISGGRLGVAMINTADNSLT-LYRASERFAMCSTSKVMAVAALLKKSE +AKAEIMNERIVLQQSDLVTWSPVTEKNLSTGMTLAELSAATLQYSDNAAMNVILRYLGGP +SGATAFARSIGDSTFRQDRTEPELNTAIPGDERDTTTPLAMAESLEKLTMGNALAEPQRQ +QLVKWLQGNTTGDASIKAGLPAIWVVGDKTGSGDYGTTNDIAVIWPDSQPPLILVTYFTQ +PLKDAKGRKDVLAEAAKIVV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Rummeliibacillus stabekisii TaxID=241244 RepID=A0A143HHY9_9BACL +--HTEEAFKQLESEFDARLGVYAIDTKTKKSV-SYQSDERFAFASTYKALATGTMLKQQS +--IKDLDKIITYTKDDLVTYSPITEKHVDTGMSLKDIATAAIRYSDNTAGNLLFNEIGGP +RGFEKALRKMGDKVTKSNRLEPELNLTLPGDLRDTSTPRALATSLQKYVIGDVLTTKKKA +LLTDLLVGNATGDTLIRAGVPKDWVVGDKSGAGSYGTRNDIAVVWPPYRKPIVIAILSSR +NTKDATYDDALIAKAAKVVVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004BF87AE +----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVMLDKYS +--LDGLDQRVTYTRKELVANSPVTEKHVGTGMTLKELCDASVRYSDNTAANLLFDHVGGP +RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLGEALPAPERE +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR +ATKDAEPSDELIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces prasinopilosus TaxID=67344 RepID=A0A1G6P237_9ACTN +--RATAAFEELERTYGARLGVYAVDTGDGREV-THHDDERFAYASTVKAFAAAAVLREHS +--PSGMDEVITYSRDDLVAHSPVTGKHVGTGMTLRELCDAAVRHSDNTAANLLFDALGGP +KGLAAALAEAGDTVTRVERREPELNQWAPGATRDTTTPRAWADDLRTFVLGDELGGRERA +QLTKWLRTNTTGDALIRAGVPEGWVVGDKTGGGGYGVRNDIAVVWPPDAAPLVMAIMSNR +GTEDAGYDDKLIEEAASVVI--- +>[subseq from] Beta-lactamase n=1 Tax=Halopolyspora algeriensis TaxID=1500506 RepID=A0A368VJV5_9ACTN +--ALREEFDRLEREFGARLGVYAVDTATGQEL-AYHADERFAYASTLKALLAGAVLRQNT +--IGELNKKITYDRGALVPYSPITKKHVASGMTLRAVLDAAVRHSDNTAGNLLFREIGGP +QGLNAVLRSIGDTTTRVARIEPELNEFTPGDIRDTSTPRALATSLRAFTVGDALAADERA +LLNTMLRTTTTGDELIRAGAPAGWQVGDKSGAADYGTRNDIAILRPPEGAPIMLAILSDR +NTQDAEYDNALIAQAATVALRAf +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. LMG 12459 TaxID=1591131 RepID=UPI001262EAB2 +--TLQLRLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD +RGELALERRVPVRKADLLANAPVSERHVGATLSVVELCRAAMIYSDNTAANLLLPLVGDP +PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPRDTTTPAAMAGTMRALLLGEVLQPVSRQ +RLIAWMRDNRTGNDCLRAGLPAGWQIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG +ATVDSAARDATLKAVAQAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis vastitatis TaxID=1905142 RepID=A0A229TGK2_9PSEU +------DFAPLERDFDARLGVYAVDIGTGREL-AHRADERFGYASTHKVFSAAAVLQRTS +--LEGLAKVLNYTRADLQPNSPVTEKHVTTGISLRDAIDAAVRYSDNTAANLLFRELGGP +AGLAAALRGIGDTTTHADRTEPGLNDLAPGDVRDTSTPRAMAVSLRAFTVGTALPPEKRT +VLTDMMRANKTGAALIRAGAPAGWTVGDKTGTGGYGTRNDIAVVWPPGRAPIVLVVLSDR +KTKDADHDDRLIAQAAKLALDSf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SCG1_KLEPN +-------------QLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQA-------------------- +>[subseq from] Beta-lactamase n=2 Tax=Labrenzia alba TaxID=311410 RepID=A0A0M7AI34_9RHOB +---VAKAIEDIETRLSARVGVSIIDTESGKTW-SHKGDERFPMNSTFKAFLCAALLDAAS +NGTVDAGREVVVEESDIVSYSPVTAKRVGGAFTIEDLCRVTVTISDNAAANIVMKEVGGP +EGVTAFLRGIGDDISRVDRWEPESNTGIPGDDRDTTTPDAAAETLRKLVLDKTLAADARA +KLTGWLEGNKVGNSTLRAGLPEGWRIADKTGAGANGSRNNIAVIWPEGRKPLVIAIYITQ +TTAAFEARNKAIASIAQAL---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDD12A8 +----EAQLAALESKHPGRICVSILDLASGKRI-EHRAGERILMCSTFKALAAALVLARVD +KGDEKLDRRIHYKKSDLVDYSPATEPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP +EAITTFCRSMGDEITRLDRTEPTLNYDTPTDERDTTTASAMLENLRRLLFTDILTAASRS +QLAAWLITNKTGDTRLRAGLPKDWLVGDKTGTNGYGNANDIAVLWPSKHAPIIVTAYCEI +PAIAADERNAIIAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ZL-24 TaxID=1933029 RepID=UPI000CD45BF5 +---TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLSGAVLARKS +--LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP +RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGIRNDIAIVWPPGAAPIAIAVLSRR +DVKDAESDDALIAGAAKVALEAf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces capillispiralis TaxID=68182 RepID=A0A561TGT2_9ACTN +------ALADLEREYGARLGVFAVDTGTGATV-VHRADERFAFCSTFKTLAAAAVLDRGP +--LDGLEQRVTYTRDDLVAYSPVAEKHVGTGMTLRQLGDAAVRHSDNAAANLLLRHLGGP +GALTAYLRGLGDRVSRLDHNEPELNRNPPGDPRDTTTPRAVTADYRALVLGDALPAAQRE +LLTDWLVRSTTGGERIRAGVPRGWKAGDKTGTGDWGRANDVAVLWPDRGAPIVLAVLTEL +PERAAAPSDPLVAEATRR----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces bingchenggensis (strain BCW-1) TaxID=749414 RepID=D7BS36_STRBB +----AREFRDLEHKFDARLGVYAIDTGTGREV-VYNDGERFAYNSTFKAMAAGAALKKFS +--LSGMDRKITYSKDVLVANSPVTEKHVDTGMTLGELCDAAVRYSDNAAANLILKELGGP +KALDATLEKLGDDVTRMDRPEPYLSEWVPGELRDTTTPRAFAKDLRAFVLGDVLAKGERA +QLTTWLRTNKTGDKVIRAGVPKGWVVGDKTGTGSYGGRNDIAVVWPPDKAPIVIAILSNR +HKKDAEPDDRLIAQAASVIA--- +>[subseq from] Beta-lactamase n=3 Tax=Burkholderiales TaxID=80840 RepID=A0A1F4G8M7_9BURK +--EWNETLANIERTAQGRLGVAMLDTGSGLQL-GWRQDERFAMASTFKAVLAGWMLALVD +QGKERLDARVHYAAGDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDSITRLDRTEPTLNEAKVGDPRDTTTPQAMLQTLQKLVLGDVLTPPSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVMWPPGGAPVLVTCYLTR +STAKPEQRDAAIAQVARAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. Root402 TaxID=1736527 RepID=UPI0006F4FB09 +--AWNEALASIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD +QGKERLDARVHYAAADVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP +AGFTAFVRSMGDEVTRLDRTEPTLNEAGVGDPRDTTTPLAMLQTMQKLVLGNALSPTSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPQGGAPVLVTCYLTR +SMASPEQRDAAIAQVARAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 94 TaxID=2035218 RepID=A0A2G7ANM7_9ACTN +--------RELEARHGARIGAFAYNLRTKATV-RHRAAERFPLCSVFKTLAAAAVLRDLD +RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGSTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PAQDAAPDSPLVAAAASVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. A7024 TaxID=1128680 RepID=UPI0013EBD8B9 +---ATREFKELERGYDARLGVYAVDTGTGREV-AYRDGERFAYASTFKALAAGAVLKKRQ +--LGGLDKKITYERDDLIANSPVTEKHVADGMTLGALCDAAVRYSDNTAANLLFDELGGP +AGLQKVLRAAGDDVTRMERNEPALSDWQPGQVRDTSTPRQLAQDLRAFTLGDELHKPERA +QLTDWLKRNTTGAELIRAGVPKQWKVGDKTGTASYGGRNDIAIIWRPNAAPLILAILTNR +KNENAEPDEKLIAEAAGAVADE- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. wa1063 TaxID=1828212 RepID=UPI000BEFF734 +------AFTALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRRYG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAELGDDVTRMERRETELNKWTPGATRDTSTPRALAGDLRAFVLGDALAKPERA +RLAQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +RDADADYDNTLIAKATSAAV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces albulus TaxID=68570 RepID=A0A059W032_STRA9 +------ELHELERKYGARLGIYAVNTGDGREV-GFNADERFAYASTFKAFAAAAVLRKYS +--LSGMDKVITYSRSDLIDHSPVTEKHVGTGMTLRDLCDAAVRYSDNTAANLLFDVLGGP +QGLAAALAGTGDTTTKVERREPELNQWSPGATQDTTTPRAWAGDLRAYALGDALGKDERE +QFTQWLRTNTTGDELIRAGVPKGWDVGDKTGGGGYAVRNDIAVVWPPGAAPIVMAIMSSR +ATKDADYDNKLIAEAASVVTK-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. RP6 TaxID=2489596 RepID=A0A3N6NTF3_9BRAD +----PAELEAYERDSGGRIGLHAENLATGRKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGQADLLEYAPVARQNLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPTAMAGNLRRLVLGEALSAQSRL +QLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPKPDAPILIAAYTQG +GTPNAAQIAALFARIGRMVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SolWspMP-5a-2 TaxID=1838281 RepID=A0A1C4SKJ7_9ACTN +-----DRLRALEEEHDARLGVFAVNVRTGRSV-AHRADERFPVCSVFKTLAAAAVLRDLD +RDGEVLGRRIHYTEADLVGGSDRTREHLAEGMTIAELADVAIRYSDNTAGNLLLRELGGP +TAVTRFARSIGDRVTRLDRWETELNSGEPGRVTDTTSPRAIGRSYARLVLGDALTGRDRA +LLTHWLLGNTTSDERLRAGVPSSWTVADKTGAGDYGTNNDVGIAWTPDGTPVVLAILSTK +HVRDAAWDHPLVRKAASLLA--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus simplex TaxID=1478 RepID=A0A098FLY9_9BACI +--ATIKKFEQLEKEYDAKLGVYAIDTGTKETV-EFHENERFAFTSTHKALAVGALLQQKS +--IEELNQRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP +AGFKKVLEGIGDNVTNPERIEPDLNVVNPSETHDTSTPIALATSLQAFTLGDALPTEKRE +LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR +DEKEADYNDELIAEATEEVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Phytoactinopolyspora endophytica TaxID=1642495 RepID=UPI00101B850E +--DLDALFSELENEFDARLGVYAVDTGTESTV-AFREDERFAYASTHKVLSAAVVLDQNS +--IDDLEETVTYSSDELAAHSPITEQHVDTGMTLRELCDAALRFSDNTAANLLLEEVGGP +DGLERALEELGDDVTSVDRYEPELNEAAPGDIRDTSTPDALATDLLKYALGDVLPAEQQG +MLNDWLRGNTTGDTLIRAGVPAGWDVGDRSGAGGYGTRNNIAVIWPPDEEPIVMAVLSSK +DEEDAEHDDALIAEAAEIALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces azureus TaxID=146537 RepID=UPI000751414C +----TARLRELEREHTARLGVYARNLRTGRTV-AYRAGERFPMASVFKTLTAAAVLRDLD +RDGEFLARRIRYTQDYVTKYSPVTQENLATGMTVGELCDATIRFSDNTAGNLLLKELGGP +TAITRFCRSVGDGVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGNALEPRDRA +RLTDWLLRNTTSTEKFRKGLPADWLLADKTGGGRHGGANDVGITWPPDGPPIVLSVLTTQ +PEEDAPADNTLVAETAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. sk226 TaxID=2034268 RepID=UPI000D1C578D +----TAAFEKLERAFDARLGVYAIDTGTGREV-IHNDRARFAYNSTFKALQAGVVLGEYS +--LDGLDRRVTYTRKDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLGGALPAAERE +QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSNR +ATKDAEPSDELIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia salmonicida TaxID=53431 RepID=UPI0009EF46D2 +----TATFAEMETKYGARLGLSVVDTGSGATV-DYREGERFPMASTFKGLACGALLQAHP +LSTGYFDQVIRYTAADIVVNSPETEKHVDTGMTVTALCDAAITQSDNTAGNMLLRLLGGP +EGFTAFLRTLGDTVSRLDRWEPELNTAIPGDERDTTTAAALVANYRVLVVGTALPEPERD +QLAAWLKASKTGAKRIKAGLPTDWIVGDKTGSPAYGSALDVAIAWPPNRAPLVLAVLTTK +PDQNAEPSNDLVAEATKAAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces albulus TaxID=68570 RepID=A0A059VQW6_STRA9 +--DFEGELQELERRYAARLGVYARNARTGQVV-AHRARERFAMCSTFKTVAAAAILRDHA +-RCAPLDKVIHYPPADLLANSPRAAEHVDTGMAVGDLCAAAIQYSDNTAANLLLRQIGGP +AGLTRFFRSIGDRESRLDRWETELNDAVPGDLRDTTTPEALGTSYGRLTVGRALDPAARE +HLVTWLKGNTTSGERFRAGLPHDWVVGDKTGTGDYASANDVGVAWTTRQTPIVLAVLTSK +DAKDAPVDNALIADAARIVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora antimicrobica TaxID=455193 RepID=A0A1I5KCS6_9PSEU +------DLAELERRYDARVGLYAINVRTGRTL-VNRPDERFALCSTFKTYAVAALLRDHG +LSSGYFDKVIRYTKDDLVSYSPETEKHVDTGMTVRALCEATMKLSDNTAANLLLRERGGP +QSIAPFARSIGDPTTRLDRWETELNTAIPGDERDTSTPAGLAAGYRALVLGDALAAPERD +QLTEWLLANTTGDECIRAGVPPTWRTGEKTGAGDYGTRNDAGVTWTEDGTPIVIAILTTR +PRQDDEYRNELLADTARAVAAH- +>[subseq from] class A beta-lactamase n=1 Tax=Hydrogenophaga sp. PBL-H3 TaxID=434010 RepID=UPI00131FD54F +--TLQDGLRDIEATARGRLGVHIIDTATGREH-GWRADERFLMLSSFKLLASALVLARAD +RSEESLERRIRYRQQDLVPWSPVTEKHVGGELSLAQLCEATITTSDNTAANLILASYGGP +AALTAFARRLGDTVTRLDRTEPELNRAASGEPLDTTTPRAMAHTVHKLLLGDALAPASRE +RLLQWLLANTTGGTHLRAGVPAGWRVGEKTGTAGD-DANDIGIAFPPQRAPLIVTAYLAE +SATDAATREAALASVGRLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Allokutzneria sp. NRRL B-24872 TaxID=1137961 RepID=UPI000A3D0303 +----NDALLELEQKFGARLGVYAMATGTGKTL-AHRADERFAFCSTFKGLASAAVLHHNP +--ISHLDTVVKYTRDDVLKNATITPKHIATGMTIRDLCDAAVRYSDGTAGNLLLRDLGGP +AKLTEYLRGLGDTVTRMDRIEPAITEATPGDPRDTTSPRAIGTTYQKLVIGDALPQEKRA +FLRDLMERNTTGAQRIRAGVPRGWTIADKTGTGDYGTANDIGILWPPNSAPIVLALMSSK +PTKDAEYNQALLAEATSVVLA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces nigra TaxID=1827580 RepID=A0A2S1IC24_9ACTN +---VRARLRELERGHGARLGVYAHNVVTGRTL-THRADERFPVCSLFKPLAVAAVLRDLD +RDGEVLARRIHYTEADLVANSDVTRAHLETGMTVAELADAAIRFSDNTAGNLLLRQIGGP +TAVTRFARSIGDRVTRLDRWETELNSAEPWRVTDTTSPRAIGGSYARLVLGEALDARDRA +RLTHWLLHNTTSVNRFRAALPPPWTVADKTGGGSYGANNDAGVVWTEEGVPLVLAVMTTR +PEQDAAYDHALIVEATRLVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A5B8Q0U6_BACME +----DREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDEVTLPERFEPDLNEVNPGETHDTSTARALAASLQTYVLGQALPEDKRE +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGSGSYATRNDIAILWPPKGDPIVLAILSDR +TEKDAEYHDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium sp. P1-18 TaxID=2024615 RepID=A0A5A7XXT0_9MYCO +-----DALAALEARIPGRLGVYALDTATGATV-THRADERFLLCSTGKVLTVAAVLKRGE +SEPGLLDQVIRYDPSDVLEWAPVTSQHVAEGMTVSQLCDAAITVSDNTAANLLVRLLGGP +QAVTTYARTLGDGVTRVDRIEPDLNVAAPGDERDTSTPTQMATNLRTLVLGDALNDDSRR +RLTDLLKANTTGDKTIRTGVPRDWVVGDKTGSGAQRESNDVAVAWPPGRAPVLLAVYVAP +TDADADAMRRVIAEATRIAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. or20 TaxID=1828016 RepID=UPI000BF2385E +----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLREYG +--LGGLARVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAGDLRAFVLGDALAEPERA +RLAEWLTTNTTGGELIRAGVPRGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +TDADADYDNTLIAKATSAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000475E203 +--RAAKALAQVERRYHSRLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAAVLLKRST +--DDELNRVINYRASDLEDYAPITKRHMGEGMTLRDLIKAAVQYSDNTAANLLLDRLGGP +AGLQKALRGMGDRTTRTDRTEPALNEAKPGDPRDTSTPRALGTDLRRFVLGDVLPEGRRQ +LLTQVLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPAGGSPIVVAVLSDR +GSKDAASDDALIKDATKT----- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060) TaxID=460265 RepID=B8IHY1_METNO +----IARLAALERQDGGRLGLTVRDTGTGRVL-SYRADERFPLCSTFKAVAAAAILARVD +RGEESLERRMTYGPEDLDTYAPVTGRRVAEGISLGDACAAAVIWSDNTAGNLMLQALGGP +EGVTAFARAQGDTVTRLDRTEPTLNTAIPGDPRDTTSPAAVTGLLERVLLGPALMADSRA +RLLGWMTESPTGTKRLRAGLPPGWTVADKTGTGENGTANVVALVRRPAGAPLLASVYLTQ +SPSAPEARNGLHAEVGRLIARTf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AG236 TaxID=2184002 RepID=A0A369BRF2_9BACI +---SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKRVDTGMTLRELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALVSSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR +TEKDAEYNDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. SB0023/3 TaxID=2584084 RepID=A0A509EAV5_9RHIZ +---PQARLVALAHGFGGRLGVAIRDTGSGRSL-ALAADERFPLCSTFKVLAAAALLARVE +QGTETLARAMPYTAADLDSYAPVARRRLEAGMPLGEACAAALVWSDNTAANLVLQALGGP +EALTAWLRRIGDPVTRLDRWEPELNTAIPGDLRDTTTPAAMLATLERILLGPALAPESRA +RLAGWMMEARTGLKRLRAGIPPTWSVGDKTGSGANGTANVVAIVRPPGRAPLLAAVYITR +SDAPDAVRDAIHAEIGRLVV--- +>[subseq from] Carbapenem-hydrolizing beta-lactamase SFC-1 n=1 Tax=Serratia fonticola TaxID=47917 RepID=UPI000260492C +-----DKLKRLENDFGGRIGVYAIDTGSNKTF-GYRANERFPLCSSFKGFLAAAVLSKSQ +QQEGLLNQRIRYDNRVMEPHSPVTEKQITTGMTVAELSAATLQYSDNGAANLLLEKIGGP +EGMTSFMRSIGDNVFRLDRWELELNSAIPGDDRDTSTPKAVAESMQKLAFGNVLGLTERH +QLMDWFKGNTTGGARIRASVPANWVVGDKTGTCGYGTANDYAVIWPVAHAPIVLAVYTSK +PDRNSKHSDAVIADASRIVLESf +>[subseq from] Beta-lactamase n=1 Tax=Marinitenerispora sediminis TaxID=1931232 RepID=A0A368T609_9ACTN +----EAAFAQLESEYDARLGVYAIDTGTEEVV-AYRPDDRFAYCSTHKAFSAAAVLDQNS +--FEELDEVVRYTEADLVPHSPVTEQHVDTGMPLIDLVDAAVLQSDNTAANLLFAELGGP +SGLQAALRETGDDVTHVDRVYPDLAEATPGDIRDTSTPQAMAATLRAYTLGDALRPEKRE +VLVDMLRRNPMSGELIRAGVPEGWVVGDKTGAGGYGTRNDIAVVWPPDDAPIVIAIMSSR +DAEDAQYDNALIAESAAVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter agglomerans TaxID=549 RepID=UPI0012B9DCD1 +-qSLNNQFEKLERQSGGRLGLAVIDTSDSAQY-SWRGNERFPLCSTSKVMAVAAILKKSE +NADTLLNKKIHISQHDMVNYNPVTMKHIGSAMSLAELSAAALQYSDNAAMNKLLAYLGGP +QHATQFARTFGDTRFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNRLVLGSALKDDQKA +TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPIVLTTYFTQ +HDKSAAARKDVLASAARVIAD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A097SR23_9BACT +--KLTKVVQAEEETLQARVGMAVFDTNTGETW-QYRGDERFPLNSTHKAFACAALLAKVD +GKSLTLDQPVSIRKEMLVPYSPITEKSLAPQMTFGEVCHAAVSYSDNTAANVVFDVIGGP +TGFTSYMRSIGDEKTRLDRKEPELNEATPGDVHDTTTPNAIVNSLRKILLGDVLSVSSRA +ELTQWMLTDQVAGALLRASLPSDWKIADKTGAGGNGSRSIVAVIWPPSKKPLVVGIYVTQ +TKASMQASNQAIAKIGTAL---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. FIRDI 009 TaxID=714197 RepID=UPI000E2828D4 +--EYAERFAALEERYDARLGVFAVDTGTEETL-AHNADDRFAYASTHKAFSAAAVLRRST +--DEDLERVITYTEEDLQEHAPIAEENLDTGMTLLEVCDAAVRYSDNTAANLLFAELGGP +SGLQEELREVGDDVTHVDRIEPELSEGAPGDIRDTSTPRAMAATLRAYTLGDVLPQDRRE +ILVDMLRRNVTGDTVIRAGVPDDWTVGDKTGTAGYGGRNDIAVLWPPEGAPIVLAVMSSR +DTEGAERDDALIADAAAIVAE-- +>[subseq from] class A beta-lactamase n=2 Tax=Xanthomonas oryzae TaxID=347 RepID=UPI0000678D84 +--MLRAQWAEIERGTGGRLGINLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANALFLLVGDS +AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRK +QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2D2CI72_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLISQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMSMAE-------------- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00039A3450 +--DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDATT +--DAELDQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEQELKGIGDNVTDAARYETELNEATPGDRRDTSTARALTEDLREYAVDDALDPTDRD +ILNAWMRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPNRAPIVLAVLSSR +DEPDASFDNALIAEAAEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003A8E3B3 +--DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDATT +--DAELDQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEQELKGIGDNVTDAARYETELNEATPGDRRDTSTARALTEDLREYAVDDALDPTDRD +ILNAWMRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPNRAPIVLAVLSSR +DEPDASFDNALIAEAAEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sacchari TaxID=56458 RepID=UPI00123E25D7 +--TLQLRLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD +RGELALERRVPVRKADLLANAPVSERHVGATLSVVELCRASMIYSDNTAANLLLPLVGDP +PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPRDTTTPAAMAATMRALLLGEVLQPVSRQ +RLIAWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG +ATVDSAARDATLKAVAQAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00048F3866 +---TDRAFAELERTFDARLGVYAVDTGDGRTV-THRPDERFAYASTCKALLAGAVLARKT +--LPQMERLVRYGQEEIISHSPITAKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP +RGLQDALRGIGDDVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LITDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR +DVKDAEPDDALIAGAAEVALEAf +>[subseq from] class A beta-lactamase n=3 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD25DEA +-hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD +KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAANLLLESFGGP +PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA +QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDIAVAWSPNRGAIVVATYCEI +PTISADERNAVVAEVGRIVAE-- +>[subseq from] Beta-lactamase n=2 Tax=Oceanobacillus picturae TaxID=171693 RepID=W9ADV7_9BACI +--KLDEQFAALEDDFDAQLGVYALDTGSNQTI-AYRAEERYAFSSTYKALAAAFVLKENT +--KEELNEIITYTVDDLVPYSPVTEKHVDTGMTLIEIGEAAVRTSDNTAGNLLFEALGGP +AKFEEALRQIGDEVTQADRYETELNEFNPEDTRDTSTPKALTTNLKKFAVGDLLTVEKRE +LFTDWLQGNATGDTLIRAGAPEGWVVGDKSGAGTYGTRNDIAVVWPPDREPIVIAIMSRH +DTEDADYDDALISEAAEVVFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. SHU 166 TaxID=1591170 RepID=UPI0003A03FBB +--TLPQRLAEIERRSGGRLGVSLLD-GGGATLgGQRQNERFPLCSTFKFLLAGAVLQRVD +RGELALERRVPVRKADLLANAPVSERYVGGTLSVVELCRAAMIYSDNTAANLLLPLVGDP +PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPRDTTTPAAMAATMRALLLGDVLQPVSRQ +RLIAWMRDNRTGNDCLRAGLPAGWQIGDKTGSNGTDTRNDIAIIWAPGRTPLLLTAYLNG +ATVDSAARDATLKAVAQAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Halopolyspora algeriensis TaxID=1500506 RepID=UPI000DF13500 +--ALREEFDRLEREFGARLGVYAVDTATGQEL-AYHADERFAYASTLKALLAGAVLRQNT +--IGELNKKITYDRGALVPYSPITKKHVASGMTLRAVLDAAVRHSDNTAGNLLFREIGGP +QGLNAVLRSIGDTTTRVARIEPELNEFTPGDIRDTSTPRALATSLRAFTVGDALAADERA +LLNTMLRTTTTGDELIRAGAPAGWQVGDKSGAADYGTRNDIAILRPPEGAPIMLAILSDR +NTQDAEYDNALIAQAATVALRAf +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. CC77 TaxID=1906739 RepID=A0A1S2KSY2_9ACTN +---TTGRLRELEREHGARLGVFAYDTGTHRMV-AYRQGERFPMCSLFKPLAAAAVLRDLD +RDGEFLARRIPYGVEDLEPWSPVTKDHVGAGLTVEELCDAAIRHSDNTAANLLLRELGGP +TAVTRFCRSAGDGVTRLDRWEPELNSAEPWRETDTTTPYAVARTYGRLVLGGLLEPRDRE +RLTGWLLGNTTSTERFRKGLPADWVLGDKTGGGSYGTNNDAGVTWPPGRPPIVLAVLTTK +PEPAALPDNPLVAGAARIVAD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. SceaMP-e96 TaxID=1100824 RepID=A0A1C6NTA2_9ACTN +--RAAKDLAQVERRYHSRLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAAVLLKRST +--DDELNRVINYRASDLEDYAPITKRHVGEGMTLRDLLKAAVQYSDNTAANLLLDQLGGP +AGLQKALRGMGDRTTRTDRTEPALNEAKPGDPRDTSTPRALGTDLRRFVLGDVLPEGRRQ +LLTHVLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPASGSPIVVAVLSDR +GSKDAASDDALIKDATKT----- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0003AAC764 +---SDREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTARALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR +TEKDAEYHDKLIAEAAKQAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI000BF9A31C +---SDREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTARALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR +TEKDAEYHDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. NRRL B-16309 TaxID=1519494 RepID=A0A0M8XZU8_9ACTN +--AADADFARLEEDFDARLGVYALDTGSGEAV-GYRAEERFAFASTIKVALFGALLERAT +--PEELEKDVTITEDDLVNWNPVTEDNVGGDMSLLELGDAALRYSDNAATNLLLEELGGP +DALDAALEEIGDDVTSVDRIEPGLNEAVPGDERDTSTPRAMATTLEAFTLGDVLPEVDRE +ILTEMMRGNTTGDDLIRAGVPDGWEVGDRTGAGGYGTRNAIAVAWPPEDDPIVVVVMSSR +DQEDAEYDDALIAQATEVVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI0009C14241 +---LRARWAEIQRGTGGRLGISLLNSVTGWHI-GQRENERFPMCITFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP +PGLTRFMRGIGDTKTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAGRDAALKAVAAAVR--- +>[subseq from] Beta-lactamase n=1 Tax=Roseovarius sp. BRH_c41 TaxID=1629709 RepID=A0A0F2RN86_9RHOB +--RLAQTIAQIEQTLDARVGLHIHDSATGWSV-SHRPNERFLMASTFKAMLCGAVLSRVD +KGTLALDEQLEITDQDILEYAPITESEIGKTMSLGELCFAALDMSDNTATNLLIDRLGGP +HKVTAFLRAIGDPVSRLDRREPDLNTFTPGDPRDTTTPAAMASTLENILAGDALSPQSRA +QLVKWMSAGGVTGALIRASTPKGWQVADKSGSGAY-NRNIVAMVTPPDQPPYVITMFLSD +TDADFATRNAAVITLSKAVMD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces roseoverticillatus TaxID=66429 RepID=UPI0004C1B58D +---ISGRLRELEQEHSARLGVFAHNTVTGRTV-AHRADELFPMCSTFKTLAVAAVLRDLD +RKGEFLAKRIHYTKKEVEDYDKITDEHVAGGMTVEELCAAAVSYSDNGAANLLLRELGGP +DAVTRFCRSIGDGKTRLDRWEPALNSAEPDRITDTTTPRAIGRTYAHLVLGNALAPEDRK +RLTGWLLANTTSDQRIRKGIPAGWTVADKTGAGSYGTNNDVAVTWSPKGAPVVMSILTTK +HEATAKGDDALVAGTAKILA--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / CIP 107115 / JCM 7437 / KCTC 9190 / NBRC 14626 / NCTC 10488 / NRRL B-5397 / IMRU 509) TaxID=446468 RepID=D7AWL2_NOCDD +-----REFERLEEEFDARLGVYAVDTGSGEEV-EHRPDERFAYASTHKALTAALVLQQNT +--PEEMEEVVTFTEEDLVDYSPVTEQHVDTGMTLMEVADAAVRYSDNTAANLLFEELGGP +DAFEDELEAIGDDVTDPERIETELNDWTPGDTSDTSTPRAMAGNLREFTLGDALPEDRRE +VLNDLLVNNTTGDALIRAGVPEDWRVGDKTGAGSHGTRNDIAVIWPPEGDPIVLAVMSSR +EAEDAEYDDALIARAAEIVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium TaxID=374 RepID=UPI0004145EF7 +----PAELEAYERDSGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGQADLLEYAPVARQNLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSRPGDPRDTTTPAAMAGNLRRLLLGEALSAQSRL +QLTDWMVNCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAAVWPKPDAPILIAAYTQG +GTPNAAQIATLFAQIGRMVAS-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003A94D94 +--DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDATT +--DAELDQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEQELKGIGDNVTDAARYETELNEATPGDRRDTSTARALTEDLREYAVDDALDPTDRD +ILNAWMRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEPDASFDNALIAEAAEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium symbiodeficiens TaxID=1404367 RepID=UPI00112A076E +------ELETYERESGGRIGVYAENLATGKKL-TWRADERFVMCSTFKASLAACVLARVD +RGEEKLAATIAYGKADLLEYAPVAKQKLAAGMSVSDMCKALVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVLGEALTPASRA +LLTEWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVAWPKPEAPILMAAYTQG +GTPNAAQIEAAFARIGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00039B6277 +--DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDATT +--DAELDQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEQELKGIGDNVTDAARYETELNEATPGDRRDTSTARALTEDLREYAVDDALDPTDRD +ILNAWMRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEPDASFDNALIAEAAEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00035E3601 +---TDRAFAELERTFDARLGVYAVDTGDGRTV-THRPDERFAYASTCKALLAGAVLARKT +--LPQMERLVRYGREEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP +RGLQDALRGIGDDVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LITDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAVAVLSRR +DVKGAEADDALIAGAAEVALDAf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces azureus TaxID=146537 RepID=A0A0K8PLQ6_STRAJ +----TARLRELEREHTARLGVYARNLRTGRTV-AYRAGERFPMASVFKTLTAAAVLRDLD +RDGEFLARRIRYTQDYVTKYSPVTQENLATGMTVGELCDATIRFSDNTAGNLLLKELGGP +TAITRFCRSVGDGVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGNALEPRDRA +RLTDWLLRNTTSTEKFRKGLPADWLLADKTGGGRHGGANDVGITWPPDGPPIVLSVLTTQ +PEEDAPADNTLVAETAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. rh34 TaxID=2034272 RepID=UPI000BF1D5A0 +----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRKHG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAELGDDVTRMVRRETELNEWAPDATRDTSTPRALAEDLRAFVLGDALAEPERA +RLRQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +TEADADFDNTLIAKAASAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=UPI00140C5D4A +----ARQLAELERNAGGRIGVFAQEVDSGRSL-AYRADERFPMCSTFALLLAGAILQRSA +AQPDLLYRHVSYRREQLIDYSPIAEQHVEQGMSVKDLCDAAMRFSDNTAANLLLEQLGGP +QEVTRFARSLGDGLSRLDRIEPELNRAEPDDPRDSTTPAAMTANLHALLFSPSLPERQRG +LLNDWLLGNTTGNLRIRAGLPAEWRVGDKTGSGGHGAANDVAVAWRPGKSPLILSVYYWG +SPAMMDERNAVIAAVARVVAAEf +>[subseq from] Beta-lactamase n=2 Tax=Quasibacillus thermotolerans TaxID=1221996 RepID=A0A0F5HPF8_9BACI +--NTNERFIQLEKEFDAQIGVYAIDTGTDQTI-EYRPEERFAFASTYKALAAAILLKQNS +--LEELEKVITYTEDELVPYSPVTEKHVDTGMTLLELGEAAVRFSDNTAGNLLFEAVGGP +QGFEQALRQIGDDVTEADRLEPDLNKFTPGDTRDTSTPRALATSLQVFAVGGLLSGDKRE +LFTDWLKGNATGDPLIRAGAPEGWEVGDKSGAGSYGTRNDIAVVWPPNRKPIVMAVLSRH +HTEDAAYDDELIAQAAKITLN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomonospora alba TaxID=183763 RepID=A0A0C2JN45_9ACTN +------DFKHLEKEYDATLGVYALDTGSGEAV-AYNADERFAYASTHKAFSAGAVLEQTP +--MDELDKHITYTEDDLLDYAPITEKHVEEGMELREVIDAAVRYSDNTAANLLFEELGGP +AGLQEALREIGDETTSVDRIEPGLNDWEPGDLRDTSTPQALATSLRAYTLGDVLPEEKRE +ILVDMMRRNTTGDDVIRAGVPGDWTVGDKTGSGAYGTRNDIAVLWPPQDDPIVVAVLTKR +DTSDAEREDALLAESAEVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Variibacter gotjawalensis TaxID=1333996 RepID=A0A0S3PS60_9BRAD +---FEDVMAEIEKSTGGRLGVGLLDLQTDKTA-FHRGDERFPMCSTFKFLLAAAVLAKAD +AREENLARRVRFEKAELLPHSPMTEQRAGDALTIAQLCEAAVTQSDNTAANLLLASLDGP +TGLTAFARKIGDTITRLDRTEPDLNDVAPGDERDTTSPRAMAEDMRKILVGDVLKIGSRE +QLSTWMRESATGKNRIRASLPMGWSAGDKTGTGPRGTSNDIAIMSPSGRQPIILTVYLTG +ATVDQTKQEAAIATVATAVIA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 2233.5 TaxID=1938839 RepID=A0A2G6Z8H0_9ACTN +----HQTLRRLEREHQARVGAFAHNLTTGARV-AYRAHTRVPLCSVFKTLAVGAVLRDLD +HNGETLARRIHYTRADLVDNSPVTGAHLATGMTIAGLCAAALQRSDNTAANLLLRELGGP +AAVTAFARSLGDRTTRLDRWETELNSAEPWRRTDTTSPAAIAHTYTRLLVGDALTPADRG +RLTAWMKVNETNTDRFRAALPKDWALADKTGTGSYGTGNDVGVAWTPDGTPVVLAVLTGK +PEQAAACDDALIADVTKVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. 14C53 TaxID=2508997 RepID=A0A5C4J4G1_9ACTN +--EVTAKLRRLEQARGTRIGAYAVDTGTGRFV-AHRADEAFPFASTFKAVACGAVLRKAR +NDPGLMDRVIRYKKSDLAAFSPVTEKHVGTGMTVAGLCHATITHSDNTAGNLVLKEIGGP +AGLTAFVRSLGDTVTRSDRVEPGLNDWRPGEKRDTTAPRAWAGSLRALTAGDALAPADRD +RLNAWMKATVTGGRRIRAGLPEGWAAGDKTGTGGYGSANDIAIVWPPSRAPLVIAILTTR +PDAGAAADERAIAETARVLAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI000491CDF5 +--DLDHEFRQLEKRFDARLGIYAIDTGTGRTV-RYQANERFAYASTFKALAAAEVLDETT +--DAELEQVVRYSTDDLVDYSPITEQHVVEGMTLRAIAEAAVRYSDNTAGNLLLDHLGGP +ERFEKELKGIGDTVTDAARYETDLNEATPGDPRDTSTARALTEDLREYAVDDALEPGDRD +TLNGWLRGNTTGGELIRAGVPDGWVVGDKSGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F5L8_9BACT +-----------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMGDNTAANLLLTTIGGP +KWLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFITDKSGAGERGSRGIIAALGPDGEPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces autolyticus TaxID=75293 RepID=A0A1P8XPP4_9ACTN +--AFTGEFKKLERAHDARLGVYAIDTGTGHEV-AYRDGERFAYASTFKALAAGAVLRKYS +--LSGLDRVIKYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDELGGP +GGLDAILEKMGDDVIQMEHYEPELSRWVPGATADTSTPRAMAEDLRAFVLGDVLGKGERA +QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGSGSYGARNDIAVVWPPDAAPIVMSLMSYR +GDKDADYDEKLIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia brevicatena TaxID=37327 RepID=UPI000687C109 +----NRTFTDLEAEHGARLGLFAIDTADGHSV-AYRDGERFPMASTFKGLACGALLHEHP +LSSGFFDRTIHYPRTDLVENSPVTEKHADTGMTVAALCDAAITVSDNTAGNQILKLLGGP +AGFTAFLRTLGDNISRLDRWETELNTAIPGDERDTTTPAALAADYRTLVVGDSLAEPERA +QLTSWLVASTTGGNRIRAGLPADWTVGNKTGSPAYGSALDVAIAWPPGRAPVVITVLTTK +SEQDAEPDNALVAAAARAAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A0D1IPB2_BACIU +----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNEQFAYASTYKVLAAAAVLKKNS +--IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGVP +KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT +ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGRRNDIAIVWPPNRAPIVLAILSNR +FTKDANYDNALIAEAAKVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. C TaxID=253839 RepID=D9VLA5_9ACTN +--RVARALAELEREHGARLGVYALETDTGRTV-THRADELFPMCSVFKTLAAAAVLRDLD +HDGSVLARRIHYTQADIARYSEWTKRHLANGLTIGELCEVSITYSDNTAANLLLRELGGP +AAVTRFARSLGDPVTRLDRWEPELNSAEPERVTDVTTPRAIARTYARLVLGDALGRADRG +LLTGWLCANTTSGARFREGLPAEWRLGDKTGGGSYGTNNDVGIAWRPHGAPLVLAVLTTK +PAQDAKADDTLVSRTARALAGAf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0006DA5099 +------AFAALEKEYAARLGVYAVDTGTGLTV-AHRDGERFAYASTFKALAAGAVLRRYG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAEPERA +RLAQWLTANTTGGELIRAGVPKGWAVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +RDADADYDNTLIAKATSAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas cucurbitae TaxID=56453 RepID=UPI00132E9987 +---LRAQWADIERGTGGRLGISLLHSATGWRL-GQRENERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQPVKIRASDMLEHAPVTKGHVGGALSVGDLCRATMIYSDNPAANRLFPLVGGP +PGVTAFLRGIGDAKTRSDRYEPEMNGFAPGEPRDTTTPVAMASTLRTLLLGAALQPASRK +QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG +AKVDDAARDAALKAVAVAVREW- +>[subseq from] carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=UPI000688AF9C +-----DKLKRLENDFGGRIGVYAIDTGSNKTF-GYRANERFPLCSSFKGFLAAAVLSKSQ +QQEGLLNQRIRYDNRVMEPHSPVTEKQITTGMTVAELSAATLQYSDNGAANLLLEKIGGP +EGMTSFMRSIGDNVFRLDRWELELNSAIPGDDRDTSTPKAVAESMQKLAFGNVLGLTERH +QLMSWFKGNTTGGARIRASVPANWVVGDKTGTCGYGTANDYAVIWPVGHAPIVLAVYTSK +PDKESKHSDAVIADASRIVLESf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1D3N9I2_BACMY +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK +DEKEVTYDNQLIADAAEVVIN-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. (strain ORS 375) TaxID=566679 RepID=H0SRU7_BRAS3 +--DLQATLAGIETDSGGRLGVALLDTASGALS-GHRLDERFPMCSTFKALLAAAILTKVD +AGAEQLSRRLPIAPSDILSYAPVTKLHVGSSLSVCELCEATVTLSDNTAANLLLATLDGP +AGLTRAIRGFGDAITRLDRIEPALNESVPGDPRDTTTPTAMAQTLAKLTTGDTLSAASRD +ILNGWLIGCKTGAAKLRAGLPGSWRVGDKTGAGDNGSSNDVAVIWPAGRAPVIVTSYLTE +TKAGDDRRNAAHAAVGRAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Labrenzia suaedae TaxID=735517 RepID=A0A1M7P9E4_9RHOB +---IDTVIARREEELGARIGVQVREREGGFNY-AHAADDRFPMASTFKALLCGAVLARVD +AGEEDLSRRITYKAADLVAYSPATEKHVKDGMTIGKLCEAAVTLSDNTAANLLLESVGGP +QGLTAFLRWSGDSTTRLDRTEPDLNEALPGDPRDTTTPAAMSETIDRLVFGDVLMTRSRA +QLRQWMIEDKVADALIRSKLPKGWTIGDKTGAGARGTRGITAFLIAPDGRTFLATIYLTE +NEADLKQRNQVIADISEAIF--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia TaxID=1817 RepID=UPI0009FBC6F7 +----TATFADMETKYGARLGLSVVDTGSGATV-DYREGERFPMASTFKGLACGALLQAHP +LSTGYFDQVIRYTAADIVVNSPETEKHIDTGMTVTALCDAAITQSDNTAGNMLLRLLGGP +EGFTAFLRTLGDTVSRLDRWEPELNTAIPGDERDTTTAAALVANYRALVVGTALPEPERD +QLATWLKASKTGAKRIKAGLPTDWIVGDKTGSPAYGSALDVAIAWPPNRAPLVLAVLTTK +PDQNAEPSNDLVAEATKTAVA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces kanasensis TaxID=936756 RepID=A0A100YAJ1_9ACTN +----RGQLRALERRHDARLGAFAHDTGTGRTV-LYRADERFPMASLFKTLAAAAVLRDLD +RDGEVLARRVHFTAAYVEQYSPVTRENVATGMTVAELSAAAICQSDNTAGNLLLRELGGP +TAITRFCRSLGDDTTRLDRWEPELNSAEPWRVTDTTTPRAIGRTYGRLVLGSALAPDDRE +RLTAWMLANTTSEERFRKGLPADWVLADKTGGGEYGGNNNVGVAWPPGRPPVVLAVLTTR +FAPDATADDALVAEAARLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI000649C59E +---SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS +--IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP +DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTARALASSLQTYVLGQALPEDKRA +LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR +TEKDAEYHDKLIAEAAKQAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Saccharomonospora glauca K62 TaxID=928724 RepID=I1D1I3_9PSEU +--SVSAELRALESRHAARLGVFALNVRSGAVV-SYRAHELFPMCSTFKTLEVAAVLRDLD +HDGTYLDRWVHYTEADLVPGSPITEQHAVTGMRVEDLCAAAIRQSDNTAANLLLRPLGGP +SGITRFCRSLGDSVTRLDRYEPDLSDGVPGDRRDTTTPAAIAADYRRLLLGRALDDADRD +RLVTWLTESVTSDTRFRAGLPSHWRVADKTGSGGYGTANDVGVAWTDDGTPLVLAVLTTK +EVEDADWDDDLVAGTAELLA--- +>[subseq from] Beta-lactamase n=2 Tax=Roseovarius sp. A-2 TaxID=1570360 RepID=A0A1V1UC03_9RHOB +-dALQQMAQEVEARIGGRIGYAMADLASGQSW-GHRANERFPMSSTFKALLCGVILMRVD +AGEERLDRRIAFGRDDLVTYSPVTEARIDKGMTVGDLCEAAITISDNAAGNLLLATVGGP +EGFTAALRGLGDRTTRLDRWETTLNEGRPGDVRDTTTPHAALATLRTLLFGDSLSPASRR +QLSDWMIADAVADDLLRASLPEGWIIGDKSGAGGHGSRSIIAVVWPSPDRPVLTAIYMTQ +NDADMSARNAAIAKIGAAMFK-- +>[subseq from] Beta-lactamase (Penicillinase) n=1 Tax=Xenorhabdus bovienii str. oregonense TaxID=1398202 RepID=A0A077NR36_XENBV +-nQITNQLSALEKNANGRLGVVLIDTADHSTI-TYHAHERFPLCSTSKMMAVSALLKKSE +TDEGLLNQRIHYQQSDIVEYSPITEKHLQDSMTLAELSAATIQYSDNTAMNLLIDQLGGT +HDVTRFARSIGDNAFRLDRKEPELNMVTPVDERDTTTPQAMADSLYKLALGNTLAATQRT +QLVEWLKGNTTGGASIRAGVPDNWIVGDKTGRCDYGSTNDIAVIWPDDKAPLILVTYFTQ +PNKDAKAHPDVLAAAARIMTQ-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces swartbergensis TaxID=487165 RepID=A0A243S9R9_9ACTN +----TARLRELEREHTARLGVYARNLRTGRTV-AYRADERFPMASVFKTLAAAAVLRDLD +RDGEFLARRIRYTQDYVTRYSPVTQENLATGMTVGELCDATIRFSDNAAGNLLLKELGGP +TAITRFARSIGDGVTRLDRWEPELNSAEPWRVTDTTSPRAIGLSYARLVLGDALEPRDRA +RLTDWLLRNTTSTEKFRKGLPAEWLLADKTGQPEYGGAHDVGITWPPDGTPIVLSVLTTQ +PERDAPADNALVARTAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNQ865 TaxID=1288081 RepID=UPI0003FC9E5E +-----RELAALEREYDARLGVYAVDTGSGREV-AYRAGERFPYASTFKALAAGVVLRTHS +--ARELDEVVTYSADDLIAHSPVTGEHVGTGMTLRDLCEAAVRYSDNAAANLVLAELGGP +AGMDAELEALGDDVTRMVRDEPELSRWHPDDTRDTSTPRALAGDLRALVLDDALGKRDRA +RLTEWLRTNTTGDTLIRAGVPGTWRVGDKTGTGSYGARNDIAVLWPPDRAPIVLAIMSNR +TQRDAEPDDALLADAASAVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4Y5QBE2_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSENHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAILRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASM------------------ +>[subseq from] Beta-lactamase n=1 Tax=Nocardia sp. Root136 TaxID=1736458 RepID=A0A0Q7NWR6_9NOCA +----TATFADMETKYGARLGLSVVDTGSGATV-DYREGERFPMASTFKGLACGALLQAHP +LSTGYFDQVIRYTAADIVVNSPETEKHIDTGMTVTALCDAAITQSDNTAGNMLLRLLGGP +EGFTAFLRTLGDTVSRLDRWEPELNTAIPGDERDTTTAAALVANYRALVVGTALPEPERD +QLATWLKASKTGAKRIKAGLPTDWIVGDKTGSPAYGSALDVAIAWPPNRAPLVLAVLTTK +PDQNAEPSNDLVAEATKTAVA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2DY68_STRVZ +-----AGLRALEREYGARLGVYARDTATGRTV-AHRADEQFPMCSVFKTLAAAAVLRDLD +HDGAHLAQRVHYTLQDVTDGGSVTERNIASGLTVAELCSAAIAQSDNAAANLLLRELGGP +TAVTRFCRSLGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIGRTYARLTLGDALDAGDRE +QLKRWLLSNTTSGDRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPVVLAILSTM +PEATTPRDDTLIARTAKLLAD-- +>[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000B442AB4 +--ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN +ILTEWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK +DEKEVTYDNQLIADAAEVVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=UPI0002F21C07 +-dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDRFPMMSTFKTLMCANALHLAE +QKKLNLNATTKVKESDLVTWSPITEKLTGQEITVQKACEATMLMSDNTAANIVLHQIGGP +EQVTQFIRSLDDKVTRLDRYEPELNQAIPGDKRDTTSPSTMVELLNTLLLQDGLSQESQQ +QLLTWMRNNKVSDPLIRSVFPQSWSIADRSGAGNQGSRGITALVWNSQRKPIILSIYLTQ +TQLDMAQRNRVINRVANLVFQQf +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=A0A5E8KPV6_9XANT +--MLRAQWAEIECGTGGRLGINLFDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLFGDP +AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRT +QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. C TaxID=253839 RepID=UPI0001B5361B +--RVARALAELEREHGARLGVYALETDTGRTV-THRADELFPMCSVFKTLAAAAVLRDLD +HDGSVLARRIHYTQADIARYSEWTKRHLANGLTIGELCEVSITYSDNTAANLLLRELGGP +AAVTRFARSLGDPVTRLDRWEPELNSAEPERVTDVTTPRAIARTYARLVLGDALGRADRG +LLTGWLCANTTSGARFREGLPAEWRLGDKTGGGSYGTNNDVGIAWRPHGAPLVLAVLTTK +PAQDAKADDTLVSRTARALAGAf +>[subseq from] Beta-lactamase n=1 Tax=Kosakonia sp. AG348 TaxID=2183906 RepID=A0A369A8C5_9ENTR +------AVARLEEHLGARIGIAVVDTASGETV-SYRGDERFPLNSTHKALLCGALLSKVD +KGELALNETTQFAQSELVTWSPVTSKFVAPAMSWQQLCSAAITESDNTAANLLAKKLGGP +AAVTRFFADSGDSVTRLDRGEPELNSAVPGDLRDTTTPLAVSHTLQKLALGELLTPRSRA +QLVQWMKEDKVADALLRSTLPKGWVIGDKTGAGDYGSRSIISIVWPKKGAPRIVSIYITD +TNATMAQSNDAIARIGKAIFS-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. RTd22 TaxID=1841249 RepID=UPI0007C44C2A +-----GELKALEREYDARLGLYAIDTGTGRQV-AYRDGERFGFHSTFKALAAGAVLRKYS +--LSGMNKLITYSRDDLVDNSPITEKHVDTGMTLRELCDAAVRYSDNTAANLLFDAIGGP +KALEREVRRVGDDVTRMERIEPELSKWVPGDTRDTTTPRALAKDLRAFALGDVLRKPERA +QLATWLKTNTTGDALIRAGVPGGWVVGDKTGSGFYGARNDIAVVWRPDAAPIVMAVLTNR +GEKDDVHDDKLIAEAASVVAD-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Rhodococcus TaxID=192944 RepID=A0A4V3FZK0_9NOCA +-------LVELEGRYDARLGVYASSSNTGRVV-EYRADERFAFCSTFKTLAVAAVLGKYP +--LSYLDTVVHYTAADLQSYAPIAEQKLDTGMTVGELCSAAVQYSDNTAANLLLQMLGGP +SAVNAYLRSIGDDVTRLDRIEPELNTAIPGDDRDTTSPRAIGTDYERLVLGDALTPDKRE +VLADWLRGNTTGAEQIRAGVPQGWTVADKTGSGDYGTSNDVGVAWTDTSDAVTISILTTR +SDRDDAADKAIIADATRLVVS-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. So13.3 TaxID=2136173 RepID=A0A5R9M9F1_9ACTN +------DFQRLERTYDARLGIYAVNTGNGREV-AYRDTERFAYASTFKAFAAAAVLRKYS +--LNGMGKVVKYSRADLLSNSPVTAKHVETGMTLRELCDAAVRYSDNTAANLLFAALGGP +KGLAAALAEAGDTATRVERREPELNEWTPGATRDTTTPRAWAANLRAFVLGDALGKDERA +QLAQWLRTNTTGDELIRAGVPKGWTVGDKTGGGGYAVRNDIAVVWPPNAAPIVMAIMTNR +GTADAPYDNKLIAEAASVVVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albulus TaxID=68570 RepID=UPI00056F17B9 +------ELHELERKYGARLGIYAVNTGDGREV-GFNADERFAYASTFKAFAAAAVLRKYS +--LSGMDKVITYSRSDLIDHSPVTEKHVGTGMTLRDLCDAAVRYSDNTAANLLFDVLGGP +QGLAAALAGTGDTTTKVERREPELNQWSPGATQDTTTPRAWAGDLRAYALGDALGKDERE +QFTQWLRTNTTGDELIRAGVPKGWDVGDKTGGGGYAVRNDIAVVWPPGAAPIVMAIMSSR +ATKDADYDNKLIAEAASVVTK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=R8DTE4_BACCE +--AIHDAFSQLEKKFDARLGVFAIDTGTNQTI-TYNADKRFAYASTHKALAVGALLQKKS +--LRDLDQVIPYTQDDLVNYNPITKDHVNTGMTLKDLCDASIRYSDNTANNLILKQIGGP +KGMEQALRGIGDTVTNSERFEPELNVLEKGEIQDTSTPRAIATSLQAFTLGNALPKEKRT +ILINFLKGNTVGDTLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNGKPIVLAIMSDR +NTKDATYNDKLIAQATKEIMD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces cellulosae TaxID=1968 RepID=UPI0004C9A449 +-----GAFRQLEREFDARLGVYALDTGTGRSV-AYQADERFAYASTFKALAVGALLQRRG +--SAGLDKVITYSQDDLVEYSPVSENFVETGMSLRELCAATLWYSDNTAANLLLEELGGP +DGLEKALERLGDDVTEMDRYEPDLSDGTPGDLRDTSTPRAIAGDLRAFLLGKALDRDERA +LLRTWMETNTTGETLIRAGLPDDWTVADKSGSAGYGGRNDVAVVWPDDGDPVVLAVMSSR +DTQGAERRDALIAKAATVAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Gha TaxID=1855318 RepID=A0A1I3P3B3_9BRAD +------DLESYERESGGRIGVHAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEKLAATISYGKADLLEYAPVAKQNLSTGMSVADMCKASVELSDNTCANLLLARIGGP +AALTAFWRSIGDTTSRLDHNEPELNRSPPGDVRDTTTPAAMAGNLKRLVTGEALSAASRA +QLTEWMVGCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWPKPDAPILITAYTQG +GTPDAAQLEAVFARIGRLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium yuanmingense TaxID=108015 RepID=A0A4E0Q2S2_9BRAD +-----SEFESYERESGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAASVLARVD +RGEEQLAAMIRYGQADLLEYAPVARENLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSQPGDPRDTTTPAAMAGNLRRLVTGEALSPASRA +LLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYTQG +GTPSVAQIASAFARIGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. CB00013 TaxID=1703945 RepID=UPI00093B6A66 +--QFHDRLMELENKFDARLGVYALDTGGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVSYSRDDLMKHAPVTERHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +AALTAFTRGLGDTVTRMDRVEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTAEKRD +FLRDLLQRTVTGAGRIRAGLPSGWTIAGKTGTGEYGTLNDIAVLWPPGKAPIVLAIMSSK +SAKDAPYDEALLAEAAKYVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Franconibacter pulveris TaxID=435910 RepID=UPI00056D6793 +--QLTAAAQQEEKTLNARLGVTVLDTATGKTA-SYRGDERFPLNSTHKALLCGALLKQAD +EKKVSLTEAVRFDKSRLVEYSPVTEKHTAPQMNWLQLCSAAVSYSDNTAANLISQKAGGP +QGVNAFLRANGDKTTRLDRLEPALNEARPGDERDTTTPQAISRTLQTLLLGDALSEASRK +QLIRWMMDDKVADALLRKSLPKSWTIADKTGAGGYGSRSIISMVWPEKGAPLVVAIYITQ +TDASLSQSNAAIARLGRVIFQQ- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=2 Tax=Enterobacterales TaxID=91347 RepID=BLAN_SERMA +--AAAKQIKKLEEDFDGRIGVFAIDTGSGNTF-GYRSDERFPLCSSFKGFLAAAVLERVQ +QKKLDINQKVKYESRDLEYHSPITTKYKGSGMTLGDMASAALQYSDNGATNIIMERLGGP +EGMTKFMRSIGDNEFRLDRWELELNTAIPGDKRDTSTPKAVANSLNKLALGNVLNAKVKA +IYQNWLKGNTTGDARIRASVPADWVVGDKTGSCGIGTANDYAVIWPKNRAPLIVSIYTTR +KSKDDKHSDKTIAEASRIAIQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Kosakonia sacchari TaxID=1158459 RepID=UPI0013630057 +------AVARLEEHLGARIGIAVVDTASGETV-SYRGDERFPLNSTHKALLCGALLSKVD +KGELALNETTQFAQSELVTWSPVTSKFVAPAMSWQQLCSAAITESDNTAANLLAKKLGGP +AAVTRFFADSGDSVTRLDRAEPELNSAVPGDLRDTTTPLAVSHTLQKLALGELLTPRSRA +QLVQWMKEDKVADALLRSTLPKGWVIGDKTGAGDYGSRSIISIVWPKKGAPRIVSIYITD +TKATMAQSNDAIARIGKAIFS-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. b84 TaxID=1827631 RepID=UPI000BF20138 +------AFTALEKEYTARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRAYG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAGDLRAFVLGDALAKPERA +RLAQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +RDADADYDNTLIAKATSAAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A1W0DC29_9NEIS +---TARQLAELERNAGGRIGVFAQEVDSGRTL-AYRADERFPMCSTFALLLAGAILQRSA +AQPDLLYRHVSYRREQLIDYSPIAEQYVEQGMSVKDLCDAAMRFSDNTAANLLLEQLGGP +QEVTRFARSLGDGLSRLDRIEPELNRAEPDDPRDSTTPAAMTANLHALLFSPSLPERQRG +LLNDWLLGNTTGNLRIRAGLPAEWRVGDKTGSGGHGAANDVAVAWRPGKSPLILSVYYWG +SPAMMDERNAVIAAVARVVAAEf +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=D9WC41_9ACTN +-----GELKALEREYDARLGLYAIDTGTGRQV-AYRDGERFGFHSTFKALAAGAVLRKYS +--LSGMNKLITYSRDDLVDNSPITEKHVDTGMTLRELCDAAVRYSDNTAANLLFDAIGGP +KALEREVRRVGDDVTRMERIEPELSKWVPGDTRDTTTPRALAKDLRAFALGDVLRKPERA +QLATWLKTNTTGDALIRAGVPGGWVVGDKTGSGFYGARNDIAVVWRPDAAPIVMAVLTNR +GEKDDVHDDKLIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces niveus TaxID=193462 RepID=UPI00084C8C36 +---LKRAFAGLERKFDARLGVYAIDTGSGRSI-THRPDERFAFASTCKALLAAVMLEKNS +--LRQLDRLVRYDRDDLAGYSPITEKHLDTGLTLRELCDATVRYSDNGAANLLFHEIGGP +KRLEAALVSIGDRVTRCDRYEDALSEALPGDLRDTSTPRALATDLRTYVLGDRLPADKRD +VLTDWLKRNTTGDKVIRAGAPAGWVVGDKTGTGGYGTRNDIAIVWPPKAAPIAIAVMSRR +DEKDAEPDDALLAGAAKVTLDAf +>[subseq from] Beta-lactamase n=1 Tax=Actinopolyspora erythraea TaxID=414996 RepID=A0A099D5U0_9ACTN +-----ADFRRLEREFDARLGVYAVDTATGREL-SYRADERFAYASTHKALTAGAVLRRTS +--IEGLDKPITYDQADLVTYSPITKKHVDSGMSLRSVLDAAVRYSDNTAANLMFDEVGGP +DGLSAALREIGDTTTHVDRIEPELNATEPGDIRDTSTPRALATSLRAFSVGNALPKDERA +LLNRMLRNVTTGDELIRAGAPDGWRVGDKSGAAEYGTRNDIAVLWPPEGAPVVLAVLSDR +ASQDAEYDNALVARAAKTALREf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces uncialis TaxID=1048205 RepID=A0A1Q4V715_9ACTN +---FADELKALERKFDARLGVHAVDTGSGREI-AHNDRERFPYASTFKALAAGAVLREQS +--PSGMNRVVKYSEDDLIPHSPVTEKHVRTGMSLSALCDAAVRHSDNAAANLLFDELDGP +EGLDEVLEEVGDDVTRMVRREPELNRWAPGETRDTSTPRALAGSLRAFVLGDALGKDDRA +TLTKWLRTNTTGDALIRAGVPEGWTVGDKTGTGSYATRNDIAVVWPPGGTPIVMAIMSSR +DEKDAVHDDKLIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Belnapia rosea TaxID=938405 RepID=UPI000B84FF77 +---ATDALAALESRQGGRLGVAILDTGTGRAL-AHRGEERFPLCSTFKFLAAGLVLARVD +RGEEWLDRRVAYGRGALVPYSPVTGPGAEAGMTMGAICDAAVTLSDNTAGNLMLDSFGGP +AGLTAWMRGLGDPVTRMDRREPELNLVPPGDERDTTTPLAMIGLMRALLLGDALRPASRE +QLAAWLVACRTGDRRLRAGLPTGWRVGDKTGTGPDIPTNDIAVAWPPGRAPILIAAYLLG +ARGSEAERSAVLAEVGRIAAQ-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00037432C4 +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFDVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +SAISNEQRAQVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 4R-3d TaxID=2559605 RepID=A0A4Y8Y4A6_9ACTN +---LKRAFAGLERKFDARLGVYAIDTGSGRSI-THRPDERFAFASTCKALLAAVMLEKNS +--LRQLDRLVRYDRDDLAGYSPITEKHLDTGLTLRELCDATVRYSDNGAANLLFHEIGGP +KRLEAALVSIGDRVTRCDRYEDALSEALPGDLRDTSTPRALATDLRTYVLGDRLPADKRD +VLTDWLKRNTTGDKVIRAGAPAGWVVGDKTGTGGYGTRNDIAIVWPPKAAPIAIAVMSRR +DEKDAEPDDALLAGAAKVTLDAf +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium genosp. SA-3 TaxID=508868 RepID=A0A4Q7F9D5_9BRAD +------ELEAYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAIIPYGQADLLEYAPVAKQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTTFWRSIGDTTSRLDHNEPELNRSRPGDPRDTTTPAAMAGNLRRLVLGEALSPTSRA +QLTEWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPRPDTPILIAAYTQG +GTPSAAQIAAAFARIGRMA---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia xishanensis TaxID=238964 RepID=UPI000A05F6EE +---ATTSFTEMEAKHSARLGVYAIDTGSGRTV-AHRDGERFPIASTFKGLACGALLRDHP +LSTGYFDQVIHYSRSEIVVNSPVTEQRVDTGMTVAELCEAAITVSDNAAGNQLLKLLGGP +EGFTAFLRSIGDTTSRLDRWEPELNTAVPGDERDTTTAAALATDYRNLVLGDVLAEPERA +QLKSWLIASRTGADRIRAALPADWTVGNKTGSPAYGSALDVAVVWPPGRSPLVIAVLSTK +FEQNAKADNPLVAEATRAAVGMf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CNZ288 TaxID=2512147 RepID=A0A4Q8BNL3_9ACTN +-----RELAALEREYDARLGVYAVDTGSEREV-AYRAGERFPYASTFKALAAGVVLRTHS +--ARELDKVVTYSADDLIAHSPVTGEHVATGMTLRDLCEAAVRYSDNAAANLVLAELGGP +AGMDAELEALGDDVTRMVRDEPELSRWNPDDTRDTSTPRALAEDLRALVLDDALDKRDRA +RLTEWLRTNTTGDTLIRAGVPETWRVGDKTGTGSYGARNDIAVLWPPDRAPIVLAVMTNR +TQRDAEPDDALLADAASAVA--- +>[subseq from] Beta-lactamase n=2 Tax=Aureimonas sp. AU4 TaxID=1638163 RepID=A0A0P0ZA15_9RHIZ +--RLEDVIGREEKAIGARLGVAIHDTHEDVWW-RHRSDERFPMCSTFKVLAGAATLKRVE +RREDDLTRRVSIAPGDVVTYSPVTEKRVGENMILAEVLQAALTMSDNTAANILIDRLGGP +EAVTRFARSIGDGTTRLDRRETDLNEATPGDPRDTTTPEAMTRTLEKLIVGDALQPTTRL +MLEGWMVANTTGDAKLRAGLPPSWRVGDRTGGGAHGTMGDIAVIWPIDRKPVVASVYITE +TDASVDRRNETIAAIGKALAS-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TaxID=1931 RepID=A0A353K576_STRSQ +---TAGAFEELEDEYDARLGVYALDTGTGREV-THRADERFAYVSTFKALLAGAVLRTYG +--EGGTDRLITYSEDDLVPDSPVTEKHVDAGMTLDALCDAAVRYSDNTAANLLLGQLGGP +KALNALLKRLGDDVTRMERLEPDLSRWDPDSTRDTSTPRAFAENLRAFVLGDVLGDAERA +RLTHWLRTNTTGDEVIRAGVPKGWTVGDKTGSGGYGVRNDIAVLWPPDRAPVVVAVMTNR +GREGDTHDNRLLAEAASVVT--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sparsogenes DSM 40356 TaxID=1331668 RepID=A0A1R1SM23_9ACTN +------DFKKLEREFGARLGVYAIDTGTGREV-AYNDGERFAYNSTFKALACGVLLDKVS +--LGGMDKKITYDRSVLLPNSPVTEKHVDTGMTLAELCDATIRYSDNAAANLILKELGGP +KALDAALEEMGDDVTRMDRPEPYLSRWVPGETRDTTTPRAFAKDLRAFVLGDALGKAERA +RLTTWLRTNKTGDTVIRAGVPKGWVVGDKTGTGSYGARNDIAVVWPPHKAPIVMAILSHR +TAKDAEPDDRLIAKAASVVA--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis thailandensis TaxID=589330 RepID=A0A229SB19_9PSEU +--QYHDRLLELEKKFDARLGVYALDTGGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVSYSRDDLMKHAPVTGQHVATGMTIRQLCDAAIRFSDGTAGNLLLRDLGGP +AELTAFTRGLGDTVTRMDRIEPLITEATPGDPRDTTSPRAFGTDYERILLGDTLAGDKRD +FLRDLLQRNATGADRIRAGLPSGWTIADKTGTGDYGTLNDIAVVWPPGKPPIVMAVMSSK +AAKDAPYDQALLAEAAKYVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas sacchari TaxID=56458 RepID=A0A0A8DSR6_9XANT +--TLQLRLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD +RGELALERRVPVRKADLLANAPVSERHVGATLSVVELCRAAMIYSDNTAANLLLPLVGDP +PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPRDTTTPAAMAATTRALLLGEVLQPVSRQ +RLIAWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG +ATVDSAARDATLKAVAQAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas cannabis TaxID=1885674 RepID=UPI000573BF00 +--MLRAQWADIERGTGGRLGISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLRRVD +QGKLTLTQPVKIRAADMLEHAPVTKRHVGGTLSVGELCRATMIHSDNPAANLLFPLVGDP +AGLTAFLRSIGDTKTRSDRYEPEMNGFAPGELRDTNTPAAMASTLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLATYLNG +AKVDAAARDAALKAVAVAVREW- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID486 TaxID=2690264 RepID=UPI00136BE945 +-------LAELEQRYGARLGVYARNVRTGRTL-AHRAGERFAMCSTFKAFAAAAVLRDRA +-GCAPLNRVVHYPPLDLLPNSPRTTEHQATGMTVADLCAAAIQYSDNAAGNLLLREIGGP +AGLTRFYRSLGDRTSRLDRWEPELNTAIPGDPRDTTTPEAVAASLEHVTLGRALAPAGRE +RLVGWLKGNTTSAARFRAGLPGEWTVADKTGTGSYATANDIGVAWTTRGTPVVLVVLSAR +PTPDAAVDEKLVEEAARVMA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TSRI0261 TaxID=1703931 RepID=A0A1Q5EIG3_9ACTN +------AFAALEKEYAARLGVYAVDTGTGRTV-AHRDRERFAYASTFKALAAGAVLRGYG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAGDLRAFVLGDALAGPERA +RLAQWLTANTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +RDADADYDNTLIAKAASAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000BB15780 +--DTRARLRELEARHGARIGAFAYNLRTEATV-RHRAAERFPGCSVFKTLAAAAVLRDLD +QHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRHSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFHAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PARDAAADSPLVAATASVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia aobensis TaxID=257277 RepID=UPI0002F7E552 +-----TEFRDLEARLHGRLGVYALDTGTGRAV-EYRPDERFPYCSTFKALAAGALLSTLP +--PAELDRRVTYTRADLVPNSPVTEQHVDQGMTVREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRAVGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLLHYVLDPSVAADDRD +VLTGLLRANTTGAALIRAGVPAGWQVGDKTGGGDYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDAEYDNAAIARAATIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=A0A3S9Y3R9_9ACTN +---FAREFKELERKYDARLGVYAVDTGTGRRV-AYKDGERFSYNSTFKALAAGAVLRKHS +--PSAMDRVIKYSRDDLVATSPVSEKHVATGMSLSELCDAAVRYSDNTAANLLLEDLGGP +KRLEAVLKGIGDDVTRMERIEPQLSRWTPGDTRDTTTPRTLAKDLRAFVLGDVLDKGDRK +QLTKWLRTNTTGDEVIRAGMPKGWVVGDKTGAGSYGARDDIAVVWPPGRSPIVVAIMSNR +FKKDADFDNKLIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. JHA19 TaxID=1577588 RepID=UPI0006E2BC83 +--DVRARLRELERGHGARLGVYAHNVVTGRTV-THRADERFPVCSLFKPLAVAAVLRDLD +RDGEVLARRIHYTEADLVANSDVTRAHLETGMTVAELADAAIRFSDNTAGNLLLRQIGGP +TAVTRFARSIGDGVTRLDRWETELNSAEPWRVTDTTSPRAIGGSYARLVLGDALDARDRA +RLTHWLLHNTTSVNRFRAALPPPWTVADKTGGGSYGANNDAGVVWTEEGVPLVLVVMTTR +PEQDAAYDHALIVEATRLVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia beijingensis TaxID=95162 RepID=UPI000835C7DE +---AATSFTELESEHAARLGVYAIDTGSGRTV-AHRDAERFPMASTFKGLACGALLRDHP +LSTGYFDQVIRYSRSELVANSPVTEKHADTGMTVAELCDAAITVSDNTAGNQVLKLLGGP +EGFTAFLRSIGDTTSRLDRWETELNSAVPGDERDTTTPAALAADYRGLVVGDILAEPERA +QLKSWLIASKTGADRIRAALPAGWAVGNKTGSPAYGGALDVAVVWPPGRDPFVIAVLSTK +AEQNAEADGPLVAGAARAAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Cryptosporangium arvum TaxID=80871 RepID=UPI0004AD4322 +--DTRDALRRLESTYDARLGVYAVDTGTGRTV-AYRADERFAYASTYKALAAAAVLDRTD +--PADLNRVVRYTAADVVDGSPVTAEHAGRGLPLGRIAEAAITKSDNTAGNLLFRELGGP +AGFERELRCLGDRVTSADRLEPALNGAVPGDVRDTSTPRALAADLRAYALGDALDVADRG +RLVGWLRGNTTGAELIRAGVPAGWIVGDKTGAAEYGTRNDIAVLWPPSGAPIVLTVLSRK +TDADAKYDNALIADAARVVS--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-1022 TaxID=1463880 RepID=UPI0004C016B4 +----QAELAELERRHGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKVFAAAAVLRDHG +-GCAPLDRVVHYPPHDLMPNSPRTEENQVTGMTVADLCAAAIRYSDNAAGNLLLREVGGP +AGLTRFLRSLGDAVSRLDRWEPELNTAVPGDPRDTTTPEAIAGSLERVTLGRALADADRE +RLVTWLKGTATSADRFRKGLPGDWVVADKTGTGDYASAHDIGVAWTTRGTPLVLAVLSGK +ATPDAPVDQALIADAAAVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus iheyensis TaxID=182710 RepID=A0A2P1WNA1_9BACI +--KLDEEFAALEDDFDAQLGVFALDTGSNQTI-AYRAEERFAFSSTYKALAGAFVLKQNT +--LEELNEVMTYTEDDLVPYSPVTEKHVDTGMTLLDIGEAAVRTSDNTAGNLLFEALGGP +AEFEEALREIGDDVSQSDRYETELNEFNPEDTRDTSTPKALATNLKKFVVGDLLPDEKRE +LFTDWLQGNATGDTLIRAGAPEGWVVGDKSGAGTYGTRNDIAVVWPPDREPIVIAIMSRH +DTEDTDYDDALIAEAAKVVFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. RB20 TaxID=2585198 RepID=UPI001295102B +--ELSGRFGALESRFGARLGVFALDTGSGHTV-EYRADERFAFCSTFKALEAGAILTTAD +--AAALDRRITYTATDLTEYAPITRQHVADGMTVRELMDAAVRYSDNTAANLLFGQLGGP +AGFQRALRSLGDQVTRSDRLETALSDATPGDPRDTSTPRTFATDLRAYVLGTVLSADNRA +LLTTMLRTNTTGTGLIRAGVPADWVVGDKTGNGDYGTRNDIAVLWPPHRAPIVLAVMSTR +HNHDDSFDNALVAQATNAAVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Xenorhabdus sp. NBAII XenSa04 TaxID=1429873 RepID=UPI000645699F +--QIINQLIALEKSANGHLGVFLINTADNSTI-GYRANERFPLCSTSKFMAASALLKKSE +KDENLLNQRINYKQSDVVEYSPITEKHIASGMTLAELSAATLQYSDNTAMNLLLDQLDGP +RGLTKFARTIGDNKFRLDRKEPELNLVKPGDERDTSTPQAMAESLYKLTLGNMLATNQRV +QLAEWLKGNTTGDASIRAGVPKDWVVGDKTGLCDYGSTNDIAVIWPTNRAPLVLVTYFTQ +PGKNAKARRDVLAEAAHILIQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces prasinus TaxID=67345 RepID=UPI0006EB67B7 +---ATGDFEELERTYGARLGVYAVDTGSGREV-AHNDDERFAYASTFKAFAAAAVLRAYS +--PSGMDEVIMYSGDDLVAHSPVTEKYVGTGMTLRELCDAAVRHSDNTAANLLFDALGGP +KGLASALEEVGDTVTRVERREPELNQWAPGSTRDTTTPRAWADALRAFVLGDELGGRERA +QLTKWLRTNTTGDALIRAGVPEGWVVGDKTGGGGYGVRNDIAVVWPPDAAPLVMAIMSNR +GTEDAGYDDQLIEEAASVVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. PpalLS-921 TaxID=1839772 RepID=UPI000B87CC51 +-----------EAEFDARLGVYAVDTGTGREV-THHADERFAYASTFKALAAGAVLRTYK +--VSGMDRVITYSEDDLVPNSPVTEKHVGTGMTLGALCDAAVRYSDNTAANLLLDQLGGP +KGLGALLAELGDGVTRMERREPELSRWVPGSTRDTTTPRAFAENLRAFALGDVLGDAERA +RLTRWLRTNTTGDEVIRAGVPDNWSVGDKTGSGGYGIRNDIAVLWPPDRAPVVVAVLSNR +DGEDDAYDNRLLAKAAAVVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. AmelKG-E11A TaxID=1100822 RepID=A0A1C6PUJ9_9ACTN +-----DELKALERKFDARLGVHAVDTGSGREI-AHNDRERFPYASTFKALAAGAVLREQS +--PSGMNRVVEYSEDDLIPHSPVTEKHVRTGMSLSALCDAAVRHSDNAAANLLFDELDGP +EGLDEVLEEVGDDVTRMVRREPELNRWAPGETRDTSTPRALAGSLRAFVLGDALGKDDRA +TLTKWLRTNTTGDALIRAGVPEGWTVGDKTGTGSYATRNDIAVVWPPGGAPIVMAIMSSR +DEKDAVHDDKLIAEAASVVAD-- +>[subseq from] Beta-lactamase n=2 Tax=Amycolatopsis decaplanina TaxID=208441 RepID=M2YH32_9PSEU +---------ELEKKFDARLGVYALDTEGGGTV-EHRADERFAFCSTFKGVAAAAVLRRNP +--LSHLETRVSYSRDDLMEHAPVTGRHVATGMTIRQLCDAAIRFSDGTAGNLLLRDLGGP +AELTAFTRSLGDTVTRMDRIEPAITEAAPGDLRDTTTARAFAADYRKIVLGDALTADKRD +FLRDLLQRNTTGAERIRAGVPSGWTVADKTGTGAYGTLNDIAVVWPPGKAPIVVAIMSGK +AAKDAPYDQALLAESAKYVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Y-H1 TaxID=2485167 RepID=A0A4V2VM37_9BRAD +----PAELEAYERDTGGRIGLYAENLATGQKF-TWRADERFVMCSTFKASLAACVLARVD +GGEEQLATMIPYGKADLLEYAPVARQNLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSRPGDPRDTTTPAAMAGNLRRLVLGEALSAQSRL +QLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDAPILIAAYTQG +GTPNAAQIATLFAQIGRMVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WZ.A104 TaxID=2023771 RepID=A0A2A4KTP2_9ACTN +----TRAFAALEKEYTARLGVYAVDTGSGRTV-AHRDGERFPYTSTFKALAAGAVLHKHG +--LSGLEHVVTYRREDLVDYSPVTEKHVATGMSLGDLCDAAVRYSDNTAGNLLFDALGGP +RGLQTVLAGLGDDVTRMERRETELNEWSPGATRDTSTPRALAEDLRAFVLGDVLGRPERA +RLTQWLRTNTTGDELIRAGAPKGWTVGDKTGAGGYGTRNDIAVVWPPDAAPLVLAVLSNR +KDAKAAFDNTLIAKAASVAV--- +>[subseq from] Beta-lactamase n=2 Tax=Acidovorax sp. 94 TaxID=2135633 RepID=A0A495HY39_9BURK +--EWNEALASIERTAQGRLGVAMLDTGSGLQL-GWRQDERFAMASTFKAVLAGWMLALVD +QGKERLDARVHYAAGDVVAYSPVSGPRASDGLTVGELCSATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDSITRLDRTEPTLNEAKVGDPRDTTTPQAMLQTLQKLVLGDVLTPPSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVMWPPGGAPVLVTCYLTR +STAKPEQRDAAIAQVARAVAT-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A0N1K823_9ACTN +---TEGAFVELERKYGARLGVYALDTGSGRTV-THRSDERFAYASTCKALLAGAVLDRNS +--LRRLDRLVRYSRDDLISNSPITERHVATGLTLRELCDAAVRYSDNAAANLLFRELGGP +RGLQDALRALGDDVTRCDRYEVALSDAVPGDLRDTSTPRALVDDLRAYVLGSALPADKRA +VLTDWLKRNTTGDHTIRAGTPDGWQVGDKTGTGGYGTRNDIAIAWPPGAAPIALAVLSRR +DAKNAESDDALLARAAEVAF--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ACT-1 TaxID=1609288 RepID=G0PXB8_9ACTN +----GRAFEALEKEYAARLGVYAVDTGTGTTV-AHRDGERFAYASTFKALAAGAVLRRYG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGALCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAGLGDEVTRMVRRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALRGPERA +RLTQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +TTADADHDNTLIAKAASAAVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SM1 TaxID=402229 RepID=UPI000CD54203 +-----------------RLGVYALATGTGATV-VHRADERFAFCSTLKTLAAAAVLDRRT +--LARLDERVRYTRDDLVDYSPVTEKHTATGMTVRDLCDAAVRYSDNTAANLLLRDLGGP +RALTAHLRGLGDPVSRLDHFEPELNGNPPGDPRDTTTPRAVATDYRDLVLGNALPPAKRA +LLTDWLVRNTTGDRRIRAGVPRGWKVGDKTGTGEWGRANDVAVLWPGRGAPLVLAVLTDR +PGRDADPSDPLIAEATRRV---- +>[subseq from] Beta-lactamase n=1 Tax=Actinopolyspora xinjiangensis TaxID=405564 RepID=A0A1H0WUJ9_9ACTN +----HEDFRRLEHEFDARLGVYAVDTATGREL-SYRADERFAYASTHKALAAGAVLRRTS +--LEGLDEPITYDRADLVTYSPITKEHVDSGMSLRSVLDAAVRYSDNTAANLMFDELGGP +EGLSAALREIGDTTTHVDRIEPDLNATEPGDIRDTSTPRALATSLRAFTVGNALPKDERA +LLNRMLRNSTTGDELIRAGAPDSWRVGDKSGAADYGTRNDIAVLWPPEGAPVVLAVLSDH +PSRDAEYDNALLARAAETALREf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces catenulae TaxID=66875 RepID=UPI0004BF5492 +---FAQDLKELERKFSARLGVYAIDTGTGREV-AYRDGERFPFNSTFKALAAGEVLKQRT +--LSGMDDVVHYSQDDLVPNSPVTEKHVKTGMTLGALCDAAVRYSDNTAANLLFDKLGGP +KGLNAALKKLGDDVTRMERPEPLLSTWDPKSTRDTTTPRALAKDLRAYVLGKALRPAERA +QLTTWLRTNTTGDTLIRAGVPKGWVVGDKTGMGSYGTRNDIAVLWPEHSSPIVVSILSSR +EAEDATPEDKVIAEAASVVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC01280 TaxID=2487424 RepID=A0A3R9WC70_9ACTN +---AARAFGDLERKFDARLGVYAIDTGTGRTV-THRPDERFAYASTCKALLAGAVLDRNT +--LRQLDRLVRYGRDELVSNSPVTERHLATGLTLRELCDAAVRYSDNAAANLLFRELGGP +RGFQDALRALGDDVTRCDRYEVALSDAVPGDLRDTSTPRALAADLRAYVLGTTLPADKRA +VLTDWLKRNTTGDHTIRAGTPDGWQVGDKTGTGGYGTRNDIAVIWPPGAAPIALAVLSRR +DTEGAERDDALIARATEVAL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. TRM68085 TaxID=2600619 RepID=A0A5N5ELW9_9ACTN +---TDRAFAELERTFDARLGVYAVDTGDGRTI-AHRPDERFAYASTCKALLAGAVLAKKT +--LPQMERLVRYGKEEIISNSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP +RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYTLGTALPAEKRA +VLIDWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVWPPGGAPIVLAVLSRR +DIKNAETDDALIAGAAKVALGAf +>[subseq from] Class A beta-lactamase n=1 Tax=Candidatus Accumulibacter sp. 66-26 TaxID=1895689 RepID=A0A1Q3VPV3_9PROT +---LNARLRELEAAAGGRLGVHFLDTASGREY-GYRAHERFPLFSSFKLLAGALVLHRVD +AGQESLARRIPYARDDLVEWSPVTERHADGAMSLGDLCEAAITTSDNTAANLILASFGGP +AGLTAYARRLGDAVTRLDRNEPDLNDPHPTQPLDTTSPGAMSRTVQQVVLGDALSAQSRR +QLQHWLLDNTTGGRRLRAGLPADWRIGDKTGTGKT-GANDIGVVWPPGGAPLVVSAYLAD +SDADIRLREATLAGVGG------ +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=UPI0005FA91FD +-dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDHFPMMSTFKTLMCANALYLAE +QKKLNLNATTTVKESDLVTWSPITEKLIGQEITVEKACEATMLMSDNTAANIVLHQIGGP +EQVTQFVRSLDDKVTRLDRFEPELNQATPGDKRDTTSPSAMVELLNTLLLQDGLSPESQQ +RLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPVILSIYLTQ +TQLDMAQRNRVINQVANLVFQQf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SRB_336 TaxID=1969380 RepID=A0A328M4H5_9BACI +-----ARLAALERRHGGRLGVAVVDTGNGRRI-AHRAEERFLMCSTCKLPIVAAVLARVD +RGAEQLGRRVVFGKSALLSHAPVCERRVGAPMTVAELCHAAITVSDNTAANLLLASLGGP +AAVTAYARSLGDDTTRLDRDEPKLNLASPDGLLDTTTPRAMLADLQTLLLGQALSGASRR +QLIAWLCASTTGLHMLRAGIPPAWRVGDKTGRGPRLETNDIAIVWPPGRQPLLVTAYYAE +SRATDAECTAVLAEVGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Microbispora rosea TaxID=58117 RepID=UPI0004C35D62 +-----SQFAALERKHGARLGVYVLETGTGASL-AYRADERFAFCSTFKALAAAAVLHQNP +--VSHLGKRVTYTGADVNSISPITKDHIATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP +ARFTAYLRRLGDTVSRMDNYEPELNRDRPRDPRDTTTPRAIAADYQKLVLGEALSAGKRA +LLKDWLVRNTTGAKRVRAGLPKVWTVADKTGTGDYGRANDIAIVWPPHAAPLVMAIMSDR +PGYHTPPKDSLIAEATARIV--- +>[subseq from] class A beta-lactamase n=1 Tax=Actinopolyspora halophila TaxID=1850 RepID=UPI0003622944 +------RFDRLEQRFDARLGVYAVDTATGEEV-THRADERFAYASTHKALSAGVVLRRNS +--IGGLNRRIHYSASDLVTYSPVTKKHVDTGMTLREVMGAAIRYSDNTAANLLFREIGGP +AALQGALRGIGDTTIHVDRTEPELNRTSPGDLRDTSTARAMAESLRKFTTGDVLSPDKRA +ILNEMLRTAQLTGDLIRAGVPSGWEVGDKSGAADYGTRNDIAVIRPPGRAPIVLAIMSDR +QDEDADYDNALIAQTARQVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. TND4FH1 TaxID=1907401 RepID=A0A4R8L9R5_9GAMM +---AAGRLAALERKYGGRLGVSMLDTGSGQQA-GHRTDERFLMCSTFKLLAVATVLGRVD +KGREQLDRRITYGKEVLLAWAPVTSRHVGADMTVGELCEAAITMSDNTAANLLLASLGGP +AVVTAFVRTLGDPLTRLDRIEPELNVGGPGDLRDTTTPAAMLGDMRALLLGDALAAVSRQ +RLIGWLRACSTGLDKLRGGLPAGWDAGDKTGSGAQGESNDVAILWPPRRAPMLVTAYYAP +ATPDKATSVRVLAEVGRITA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia paucivorans TaxID=114259 RepID=UPI000312C307 +----DQPFAALEAEHGARLGVFAVDTADGRSV-AYRAGERFPMASMFKGLACGALLREHP +LASGFFDQVIRYPRTDLVEYSPVTEQHVDTGMTVAALCEAAITRSDNTAGNQILKLLDGP +AGFTAFLRTLGDDVSRLDRWETELNTAIPGDERDTTTPSALAADYRALVVDDGLAEPERT +RLSSWLIANTTGDSRIRAGLPADWTVGDKTGSSAYGCALDIAVTWPPGRAPIVIAVLTAK +SEQDAEPDNALVAAAARTAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Labrenzia sp. Alg231-36 TaxID=1922224 RepID=UPI000D55AC58 +---VAKAIEDIETRLSARVGVSIIDTESGKTW-SHKGDERFPMNSTFKAFLCAALLDAAS +NGTVDAGREVVVEESDIVSYSPVTAKRVGGAFTIEDLCRVTVTISDNAAANIVMKEVGGP +EGVTAFLRGIGDDISRVDRWEPESNTGIPGDDRDTTTPDAAAETLRKLVLDETLAADARA +KLTGWLEGNKVGNSTLRAGLPEGWRIADKTGAGANGSRNNIAVIWPEGRKPLVIAIYITQ +TTAAFEARNKAIAGIAQAL---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseus TaxID=1911 RepID=UPI0013B731A0 +----GRAFEALEKEYAARLGVYAVDTGTGTTV-AHRDGERFAYASTFKALAAGAVLRRYG +--LGGLERVVTYRREDLVDHSPVTEKHVDTGMSLGALCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAGLGDEVTRMVRRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALGGPERA +RLTQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +TAADADHDNTLIAKAASAAVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00035E3026 +--DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQADQRFAYGSTFKALAAAEVLDATT +--DAELDQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEQELKGIGDNVTDAARYETELNEAIPGDRRDTSTARALTEDLREYAVDDALDPTDRD +LLNAWLRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEADASFDNALIAEAAKVVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NEAU-LD23 TaxID=2486417 RepID=A0A3M8VRP7_9ACTN +-----GELKALEREYDARLGLYAIDTGTGRQV-AYRDGERFGFHSTFKALAAGAVLRKYS +--LSGMNKVITYSRDDLIDNSPITEKHVDTGMTLRELCDAAVRYSDNTAANLLFDAIGGP +KALEREVRRVGDDVTQVERIEPELSKWVPGDTRDTTTPRALAKDLRAFALGDVLRKPERA +QLRTWLKTNTTGDALIRAGVPKGWVVGDKTGSGYYGARNDIAVVWRPDAAPIVMAVLTNR +GAKDDVHDDKLIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. 'Ferrero' TaxID=2033654 RepID=A0A2A5NSH2_9MICO +----AAAFAALEQRFRARLGLVVLDPRDGTSV-QYRADERFPFASTNKVFIAAAVLDRSS +--TADLDAVVHFDRSDLLAYAPVTERHLDTGMTVRELVDAALRYSDNTAANLLVERLGGP +AAVQRWLRSTGDRVTRVDRVEPDLNTAVPGDPRDTTTPLQFAADLRAVLLGDVLSPAARA +LLRSTMAANTTGDATIRAGVPSGWEVADKTGTGERGVRNDIGIVTPAGGDPLVVVVTTRT +DDPDAAPSDALVAAATRA----- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W5T2X4_ECOLX +-----VKVIDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTMGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTT- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia gamkensis TaxID=352869 RepID=UPI0007A398F8 +---ASTSVADLEARYGAQIGLFAVDTGTGRTV-THRADERFPFLSTFKALAAAALLRSHP +LDTGYFDRVIRFDEADLVEHSPVTSAGVVDGMTLARVAEAAITRSDNTAGNLLLREIGGP +EGLTAFLRTLGDPASRLDRWETELNTAIPGDERDTTTPAALAADYRASALGDALGAPERD +QLVAWLKANTTGGERIRAGLPANWVTGDKTGTGSYGSANDVAIVWPEGGAPIVIAIMSRK +SDADAEANSDLLVEVTKVAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 840.1 TaxID=2485152 RepID=A0A3N1SCA7_9ACTN +--RTERAFRDLERKFDARLGVHALDTGSGRTV-THRPDERFAFASTCKALLVGAVLDKNS +--LRQMDRLVRYGRDDLVSASPITERHVDTGMTLRELSDAAIRYSDNTAANLLFHELGSP +YALQKALRSLGDEVTRCDRYETALSDATPGDPRDTSTPRALATDLRAYVLGSTLPADKRA +VLTDLLRRNTTGDHTIRAGVPDHWQVGDKTGTGGYGTRNDIAVIWPPGAAPITLAVLSRR +STKDAERDDALIAGAAKVAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF15084 +-----HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS +--IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP +SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS +FLIDLMKRNTTGDNLIRAGVPAGLEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH +AKEDAKYDDKLIANATKIVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Paenibacillus polymyxa TaxID=1406 RepID=A0A5B8JW12_PAEPO +-----VVFKQLETKFDARLGVYIIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS +--NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP +EGFEKAMRDNGDTVVMANRYETELNEAIPGDLRDTSTPNALANSFKVLTIDDSMPNDKQE +LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR +DTEDAEYNNALVAEAAKAAFK-- +>[subseq from] Beta-lactamase n=2 Tax=Acidovorax sp. 100 TaxID=2135635 RepID=A0A3L9YQ13_9BURK +--AWNDALASIERSAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD +QGNERLDARVHYPATDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDEVTRLDRTEPTLNEAAVGDPRDTTTPLAMLQTMQKLVLGNALSPMSRA +WLQRWLVETSTGDKRLRAGVP-GWRVGDKTGTAGSGTANDIGVLWPQDGAPVLVTCYLTR +SKASPEQRDAAIAQVARAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces xiaopingdaonensis TaxID=1565415 RepID=UPI00030010B6 +----KREFAALERKFDAKLGVYALDTGSGKEI-AHRPDTRFAHASTFKALLAGVILEQTS +--AADLDERVEYTKKDLPEYSPITERHASDGMTLRELCDAAVRHSDNGAANLLVRHLGGP +AELQKALRASGNRVTHIDRYETDMSAAEPGDVRDTSTPRALADSLRTYAVQNTLPAKKRT +MLTDWLKRNTTGDDLIRAGAPKGWKVGDKTGNGGYGTRNDIAVVWPPKSDPIVLAVLSKR +DTKNAEHDDALVADAAEVALE-- +>[subseq from] Beta-lactamase n=2 Tax=Nocardia africana TaxID=134964 RepID=A0A378WL71_9NOCA +---ALAEFHDLEARLHGRLGVYALDTGTGRAV-EYRSDERFPYCSTFKALAAGALLSTLP +--PAELDRRITYTRADLVPNSPVTERHVDQGLTLREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPSVAAGDRD +VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGDYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDAEYDTAAIARAATIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. B2-3-4 TaxID=2589959 RepID=A0A503WKT4_9RHIZ +------KIRRIEAKSGGRLGVACRIAGTTTQF-GYRENELFPMCSTFKALMAALVLHRVD +GGIEQLERVIKVPHNAVIANSPTTKKFAGGEMTVAQLCEAAVTVSDNGAANLLLASFDGP +PQLTAYLRSIGDTVTRLDRIEPELNESVPGDPRDTTSPLAMIEDYERLALGDALSPKSRK +QFVDWLVANKTGDERIRAGLPKGWRCGDKTGTGARGSTNDAAVIWPASGNPILISVYLTG +TKQALAKRNATIASVSRALVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A222U9C1_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIY--- +----------------------- +>[subseq from] Beta-lactamase family protein n=2 Tax=Rhizobium TaxID=379 RepID=L0LX26_RHITR +----EAQLAALESKHPGRICVSILDMASGKRV-EHRSGERILMCSTFKALTAALVLARVD +KGEEKLDRRIHYKKSDLIDYSPATEPNVGDNMTVGELCEAAVTLSDNTAANLLLASFGGP +EAITTFCRSIGDEITRLDRTEPTLNYDIPNDERDTTTASAMLENLRRLMFTDVLTPASRS +QLAAWLITNKTGDARLRAGLPKDWLVSDKTGTNGHGNANDIAVLWPSNRAPIIVTAYCEI +PAITADERNAIIAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces flavidovirens TaxID=67298 RepID=UPI0003F732EE +----ARELKELEREFDARLGVYAVDTGTGREV-AYNDGERFPYASTFKALAAGAVLREYA +--PSGMGRVIKYSRDDLIAHSPVTEKHLETGMSLSALCDAAVRFSDNTAANLLLDQLGGP +RGMDAVLEELGDDVTRMERREPQLSQWDPRSTRDTTTPRALAGDLRAFVLGDALGKGERA +QLTKWLRTNTTGAELIRAGMPKDWVVGDKTGTGSYGARNDIAVVWPPGTAPIVVAIMSNR +SEKNADHDNELIAEAASVVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0004854FA6 +--DLHHELRQLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLRHLGGP +ELFEQELKEIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEPDASYDNALIAEATEVVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia sp. CICC 11023 TaxID=2545717 RepID=A0A5N0EPA2_9NOCA +---SAAELAALEKKYDARIGVFAVDTGSGKTL-TARADERFPFLSTFKGLAAAALLKAHP +LDTGYFDRVIHYTDADLLSYSPVTKTKVAEGMTVAQLAEAAITQSDNTAGNLLLRELGGP +QGLTGFLRGIGDQVSHLDRWEPELNTAIPGDERDTTTPAALATDYRALVVGDALGAPERA +RLTGWLKANTTGDKRIRAGVPAGWSTGDKTGTGDYGCAHDAAVTWPDGSAPLVIAIQTCK +SVKEAESSNDVIADATRVAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces davaonensis (strain DSM 101723 / JCM 4913 / KCC S-0913 / 768) TaxID=1214101 RepID=K4RBG2_STRDJ +---ATARLRALEEEHGGRLGVYAHNLATRRTV-RHRADELFPMCSLFKTLAAAAVLRDLD +RDGEVLNSRLHYTEADLVDVPDVIREHLSDGMTVAALAELAITHSDNTAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWEPELNTAEPWRVTDTTSPAAIGRTYGRLVLGDALNRRDRE +QLTEWLLRNTTSTARFRAGLPPAWTLGDKTGSGSYGTANDVGVAWTETGAPIVLSVLTTK +PEQNAAWDNALVAKTAKVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID8016 TaxID=2706098 RepID=UPI0013D99A75 +----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLGKYS +--LDGLDRRVTYTRKDLVANSPVTEKHVGTGMTLKELCDASVRYSDNTAANLLFDHVGGP +RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLGGALPAPERE +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR +ATKDAEPSDELIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Comamonas testosteroni TaxID=285 RepID=UPI00130E46EA +-----RELAKLEAMSGGRLGLFVRDTATGQQA-GWRSQERFPLCSTFKTLLAAHALNEVQ +QGRLPLDRTFQYRKADLVPWSPITEKHADTDMTLQQLCEAAVVVSDNTAANLLLKATGGP +EGLTAWLRLMGDHQTRLDRFEPELNTAVKGDERDTTTPAAMLGSLQKLLVGTVLPEAERN +LLLQWLVASRTGDKRLRAGMPADWKAGGKTGSGENGTANDTLIVWPTTKKPLLVTAYFTG +SQLDAAGRDAVLAQVGDAVK--- +>[subseq from] Beta-lactamase n=2 Tax=Caulobacter sp. (strain K31) TaxID=366602 RepID=B0SWD0_CAUSK +----SRSMAALEARSGGRLGVAVLDTAGGKAF-AYRGDERFAMCSTFKALIAGFVLKRVD +QGKERLDRRITYGKGVLLAHSPATEKHVGDGMTVGELCEATITLSDNAAANLLLRTFGGP +PALTAFLRGLGDKVTRTDGYEPGINVVEPGEVHDTTSPNAMLATLRTLTLGSALAPASRQ +RLVGWLVANQTGDKRLRAGLLAGWTVGDKTGSWGKGTTNDIAVIWPTGRPPLLITAYLAD +SRLDSDGRDAVIAEVARLVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0014315680 +----DREFRRLEKRFDARLGIYAIDTGTGRTV-CYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKEIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces griseoviridis TaxID=45398 RepID=A0A3S9ZI84_STRGD +----VDRLRALEEEHGARLGVFAHNVRTGRTV-AHRADERFPICSVFKTLAVSAVLRDLD +RDGEVLGRRVHYTEADLVGGSDRTREHLAEGMTVAELADVAIRYSDNTAANLLLRELGGP +TAVTRFARSIGDRVTRLDRWETELNSGEPGRVTDTTSPRAIGRSYARLVLGDALADRDRA +LLTHWLLGNTTSGERLRAGVPSTWTVADKTGAGDYGTNNDVGVAWTPDGTPVVLAILSTK +HVQDAEWDHPLVKEAASLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003615D6A +--DLHHEFRQLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLRHLGGP +ELFEQELKEIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEPDASYDNALIAEATEVVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus wratislaviensis TaxID=44752 RepID=A0A402CDY9_9NOCA +-qSLDAKIDALEAQYATRIGVTAVDPASGAVY-NHRGDERFAMCSTFKAYASAAVLRKIE +DGSTSLDKTVVIEPGDLVENSPVTAAAVGTPMTLGQIAEAALTRSDNTAGNYLLREIGGP +QAITALARDLGDESTRLDRWETELNTALRGDPRDTTTPAGLAQGFRALLLGDALDAASRD +QLVDWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWSPDGSPVVLAVLTDS +LTEDAQGNNQAIADTTAAVIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rapamycinicus TaxID=1226757 RepID=UPI000EF80019 +--AVTGEFKKLERSYDAHLGVYAIDTGTGHEV-AYRDGERFAFASTFKALAAGAVLRKYK +--LSGLDRVIRYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGV +KGLDATLEKLGDDVIQMERIEPELSRWVPGETHDTTTPRAMAKDLRAFVLGDVLDKGERA +QLTKWLRTNTTGDELIRAGMPKGWQVGDKTGSGSYGARNDIAVVWRPDAAPLVMAIMSYR +GDKDTPFDNKLIADAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. OV198 TaxID=1882787 RepID=UPI000BE36FE1 +--DTRARLRELEARHGARIGAFAYNLRTEATV-RHRAAERFPGCSVFKTLAAAAVLRDLD +QHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRHSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFHAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PAQNAAADSPLVAATASVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003614918 +--DLHHEFRQLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLRHLGGP +ELFEQELKEIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEPDASYDNALIAEATEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0004839A97 +--DLHHEFRQLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLRHLGGP +ELFEQELKEIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEPDASYDNALIAEATEVVIA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=A0A0D4DHB7_9ACTN +----AGEFKKLERKFDARLGVYAVDTGTGREV-AYNDGERFAHASTFKALAAGAVLRKYA +--PSGMDKVIKYSKSDLVESSPITEKHIETGMTLRELCDAAVRFSDNTAGNLLFDALGGP +KGLDAALAKIGDDATRMERREPELNRWAPGEQRDTSTPRALAKDLRAFVLGNLLGKGERA +QLTKWLRTNTTGGELIKAGMPKDWKVGDKTGAGSYGTRNDIAVVWRPHAAPIVVAILSHR +NKAGAHYDNKLIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004BD8133 +------RLRALEREFGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDRRP +--GARLDERVSYSTADLVTYSPVTEKHTADGMTLRQLCDAAVRYSDNTAGNLLLRDIGGP +RGLTAYARRLGDRVTRLDHVEPELNSNPPGDPRDTTSPRAIAADYRALVLGDALPAAGRA +LITDWLVRNTTGDRRIRAAVPRGWRVGDKTGGGEWGRGNDVAVLWPGGRPPLVLSVLTER +TDRAASPSDELVAEAARRVLD-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Pantoea TaxID=2630326 RepID=A0A5M7NNI1_9GAMM +-qSLNNQFEKLERQSGGRLGLAVIDTSDSAQY-SWRGNERFPLCSTSKVMAVAAILKKSE +NADTLLNKKIHISQHDMVNYNPVTMKHIGSAMSLAELSAAALQYSDNAAMNKLLAYLGGP +QHATQFARTLGDTTFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNKLVLGSALKDDQKA +TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPLVLTTYFTQ +HDKSAAARKDVLTSAARVIAD-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=A0A328MX27_9ACTN +----DQEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT +--DAQLDRVVRYSTRDLVAHSPITEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP +AGFEAKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALEPADRD +VLRARLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR +DRKDATPADAVIAQATRVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Bordetella hinzii TaxID=103855 RepID=A0A448LQJ4_9BORD +--DAQRQLARLEAREGGRLGVSLLDVQSGYAI-AYRADERFALCSTFKLLAVGAVLTRVA +RGEDDLSRPMRLSAADIVDYSPVTQQRLNEGMTLGQLCEAALLWGDNTAANLLLSTIGGP +PGVTAYARALGDGATRLDRLETALNEARPGDERDTTTPAAMLGNLRQLVLGDALPAPERE +RLRDWLMQCRTGQQRLRAGLPAGWSLGHRTGAGGHGTCNDIGVAWPTPTTPVVISVYLTE +SPLDLPGRERVLAEAARILAH-- +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas sp. MG34 TaxID=2600296 RepID=UPI001372B34C +--KLDEQFAVLEDDFDAQLGVYALDTGSNQTI-AYRAEERFAFSSTYKALAAALLLEQNE +--MEELNEVITYSEDDLVTYSPVTEKHVDTGMTLLEIGEAAVRTSDNTAGNLLFDALEGP +AKFEEALRQIGDDVTQSDRYETELNEFNPEDTRDTSTPKALATNLKKFAVGDLLTDEKRE +LFTDWLQGNATGDTLIRAGAPEGWVVGDKSGAGTYGTRNDIAVVWPQDREPIVIVIMSRH +DTEDADYDDALISEAAKVVFD-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonadaceae bacterium NML93-0792 TaxID=2032566 RepID=A0A2A3VLD3_9GAMM +--ALDDALAALESAAGGRLGVALLDTGTGRRF-GRRDEARFPMCSTFKALLAGAVLHAVD +RGRVRLDQRVDIGAEDLVTYSPYVDTRVADGARVDALCRATVTLSDNAAANLLLPLVGGP +PGLTALLRELGDPVTRLDRWEPALNEAAPGDPRDTTSPRAMVDSLQRLLFGTALHPPSQA +VLAAWLIENRTGDARIRAGVPADWRVGDKTGTCGAGTAADVAVLYPPGRAPLLLAIYVHG +ATLDGPAIDALHADATRLLV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomonospora sp. PA3 TaxID=2607326 RepID=UPI0012DD81B4 +------DFRKLEKEYDATLGVYALDTGTGETV-AFNAGDRFLFCSTHKVFSAGAVLDQTP +--MEDLDKRITYTEDDLLEWAPITEKHVDEGMELLDVIDAAVRYSDNTAANLLFEELGGP +AALQEEMRAIGDETIRFDRIEPDLSYTEPGDLRDTSTPQAMVSSLRAYALGDVLPQEKRE +ILVDMMVRNTTGDDTIRAGVPDDWTVGDKTGTGNYGTRNDIAVLWPPEEEPIVVAVMSTR +DTADAEHDDALLAESAEVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=V5NET2_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPK------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas sp. J31 TaxID=935851 RepID=UPI0004046DEB +----APDFAALEAASQGRLGVAVLEAGNGRYLaGHRADERFPMCSTFKALLAAAVLARAD +RGALDLDERLPVRAADLVPHAPVTRRHVGKDLGVRDLCRAIVTISDNTAANLLFARIGGP +AALTAFLRGLGDTVTRSDRLEPEMNGFVPGDPRDTTSPRAMATSLRRCVAGAVLAPASRL +QLADWLIDNTTGDDCLRAGIGPEWRVGDRTGSNGTDIRNDVAVLWPLGGSPWVVAAYLEG +SRVDSAARDAVLARAGQLAV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. WAC06614 TaxID=2487416 RepID=A0A429S6E7_9ACTN +--DITARLRALEGEHAARLGVFAYDTATGATV-AHRADERFPMCSLFKTLAAAAVLRDLD +HDGEYLARRVRWTAEDVRAHAPVTGERANLELTVGELCAAAISFSDNTAANLLLRDLGGP +TAVTRFSRSLGDPVTRLDRWEPELNSAEPDRGTDLTTPRAIGRTYARLVLGRALERPDRE +RLTGWLLANTTSGKRFRAGLPAGWRLADKTGGGSYGTNNDVGIAWPPGRPPVVLAVLTTH +ASPTAAADDALVAEAARLVS--- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5PQJ2_9BACT +----NANFAQLETRTKSRIGVAAVDLSTNRRV-DYRAEERFLMCSTFKVLAAAGVLKRVD +ENKEKLDHFVTYGEAQLLSYAPVTRAHVKEGLTLETLCAAAVEQSDNTAANLLLESIGGP +EKVTELARSLGDKFTRLDQTEPELNVAKPGQDDNTTTPAAMCADLQRLLTSDFLTTASRT +KLEGWMRQNQTGSKLIRAALPSDWQVGDKTGRSGDGATNDIAIVRPPGGGPIFLAIYTVD +PSETPEAREKLVAEVAKTAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces orinoci TaxID=67339 RepID=UPI000D657AE3 +-----AAFKGLEQRFGARLGLYALDTGTGREV-TYRADERFAHASTFKALATGALLRHAS +--DADLEQVVNYGPRDLQKWAPVTAKHTGTGMRLRELADAAMRYSDNTAANLILDRLGGP +SGLQRQLFELGDSTTNINRPEPDLNEATPGDPRDTSTPRALAADLRRFVLGDALSPGRRR +LLTDWLMGNTTGGPYIRAGVPAGWKVGDKTGNGGYGTRNDIAVAWPPSGRPVVIVILSDR +AKANASSDDSLIADATKAAVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Variibacter gotjawalensis TaxID=1333996 RepID=UPI000BBAC6DB +---FEDVMAEIEKSTGGRLGVGLLDLQTDKTA-FHRGDERFPMCSTFKFLLAAAVLAKAD +AREENLARRVRFEKAELLPHSPMTEQRAGDALTIAQLCEAAVTQSDNTAANLLLASLDGP +TGLTAFARKIGDTITRLDRTEPDLNDVAPGDERDTTSPRAMAEDMRKILVGDVLKIGSRE +QLSTWMRESATGKNRIRASLPMGWSAGDKTGTGPRGTSNDIAIMSPSGRQPIILTVYLTG +ATVDQTKQEAAIATVATAVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia jinanensis TaxID=382504 RepID=UPI0012E3BC9C +----TQQFADLEAAHGARLGVFVLDTTDGRSV-SYRDGERFPMASTFKGLACGALLREHP +LSSGFFDRVIQYPRTDLVANSPVTEQHVDTGMTVAALCEAAITVSDNTAGNQILKLLDGP +AGFTAFLRTLGDNTSRLDRWETELNTAIPGDERDTTTAAALAADYRALVVGDSLAEPERA +QLSAWLVASATGGNRIRAGLPAGWTVGNKTGSPAYGSALDVAIAWPPGRAPIVLAVLTTK +SEQDAEPDNALVAAATRAAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus senegalensis TaxID=1936063 RepID=UPI000A3142DB +--STNDVFRQLEDEYDARLGIYALDTGTNQTV-KHREDERFAYGSTHKALSVGVLLQQNN +--LNELDQTITFTYDDLVNYNPITEKHVDTGMTLREISDAAIRHSDNTAANLILEQIGGP +EGFKEALRKIGDDVTNPERIEPELNEVEPGETQDTSTPEALATSLQAFTTGDALPSEKQD +LLIDWLKRNTTGDALIRAGVPEGWEVGDKTGSASYGTRNDIAIIWPPNGDPIFLAVLSSR +DQKDAESDDELIEKATEEVF--- +>[subseq from] BKC/GPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Shinella sp. AETb1-6 TaxID=2692210 RepID=UPI001367CDAA +--ALGKRLAELEARHKGRIGVAIHNLATGARL-GHRADERFLMCSTFKALLAAHILARVD +RGEEALDRRIVVKTTDLVDWSPVVEKHVGDAISVAALCEATITLSDNAAANLLLAASGGP +EAVTAFLRGFGDTVTRLDRTEPTLNYDSPADERDTTTPAAMTDTLHRLVLGDVLSPQAKA +QLAAWLVMNKTGDTRLRAGFPANWMTGDKTGTNGAGNANDVAIAWSPDRGAIVVTAFVEM +PGISGDDRNAIIAEIGRVAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia alba TaxID=225051 RepID=UPI00104D921A +----SATFADLESKYGARLGLSVLDTGSGAAL-AYRADERFPMASTFKGLACGALLQAHP +LSTGYFDQVIRYTPADLVVNSSETGKHLDTGMTVAALCDAAITLSDNTAGNMLLRLLGGP +AGFTAFLRTLGDPVSRLDRWEPELNTAIPGDERDTTTAAALVANYRALVVGTALPEPERA +QLATWLKASKTGATRIKAGLPADWIVGDKTGSPAYGSALDVAVAWPPNRAPLVLAVLTTK +PKRDAEPANDLVAEATEVAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Kosakonia pseudosacchari TaxID=1646340 RepID=UPI000A369AD2 +---------LQEERLSARIGIAVIDTASGETV-SYRGDERFPLNSTHKALLCGALLSKVD +KGELALNETTQFAQSDVVTYSPVTSKFVAPAMSWQQLCSAAITESDNTAANLLAKKLGGP +AAVTRFFADSGDSVTRLDRAEPELNSAVPGDVRDTTTPLAVSHTLQKLALGSALTPASRA +QLVQWMKEDKVAGALLRSTLPKGWVIGDKTGAGGYGSRSIISIVWPKKGAPRIVSIYITD +TKATMAQSNDAIARIGKAIFS-- +>[subseq from] Class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=A0A1V0I6E5_9VIBR +-dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDRFPMMSTFKTLMCANALYLAE +QKKLNLNSTTKVKESDLVTWSPITEKLTGQEVTVQKACEATMLMSDNTAANIVLYQIGGP +EQVTQFIRSLDDKVTRLDRYEPELNQAIPGDKRDTTSPSAMVELLNTLLLQDGLNQESQQ +QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPVILSIYLTQ +TQLDMAQRNRVINRVANLVFEQf +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. 13-12-16 TaxID=1570823 RepID=A0A1X4ICE4_9ACTN +----VRRLRELEQRHSARLGVYARDTATGRTV-RYRADERFPMCSLFKTPAVAAVLRDLD +RDGEFLAERIRYTEKDVTDYAPVTGENLASGMTVAELCDATIRHSDNAAGNLLLRELGGP +AAVTRFCRSIGDRTTRLDRWEPELNSAEPWRETDTTTPYAVGRTYARLTLGTALAPGDRE +RLTGWLLANTTGDAKLRAGLPADWAVAEKTAGGKYGTNHDVGVALPPRRAPLVLAVLTTK +REPDAAPDNPLIAETAALLAE-- +>[subseq from] class A beta-lactamase n=2 Tax=Bacillus aciditolerans (strain JCM 32973 / CCTCC AB 2017280 / YN-1) TaxID=72581 RepID=UPI00140546B1 +--TTDEEFTQLESKFDARLGVYAYDTETEKSV-VHREDEKFAFASTYKALAAGAMLQQKS +--INELDEIITYTKDELVTYSPVTEKHVDTGMSLKDIAEAAIRYSDNTAGNLLFNEIGGP +VGFETALREIGDMVTESDRFEPDLNFTAPGNSRDTSTPRALAQSLQTFVVSDILPSEKRA +LMTDWLVGNTTGDTLIRAGVPEGWVVGDKSGAASYGTRNDIAIVWPPERDPIVIAILSDR +SSEDATYDDTLIAEATKIVIE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. YK2 TaxID=1860096 RepID=A0A1E4Y600_9RHIZ +----EAQLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD +KGDEKLDRRIHYKKSDLIDYSPATKPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP +EAITTFCRSIGDEITRLDRTEPTLNYDTPTDERDTTTASAMLENLRRFLFTDILTAASRS +QLAAWLIANKTGDTRLRAGLPKDWLVGDKTGTNGYGNANDIAVLWPSKRAPIIVTAYCEI +PTIAADERNAIIAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium zhanjiangense TaxID=1325107 RepID=UPI0010088FD3 +------ELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGQADLLEYAPVAKQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSIGDTISRLDHNEPELNRSRPGDPRDTTTPAAMVGNLRRLVLGEALSPTSRA +QLTEWMVNCKTGANRLRGGLPAGWRIGDKTGNNGKDASGDIAVVWPRPDAPILIAAYTQG +GTPSAAQIAAAFARIGRMA---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD75FBE +----EAQLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD +KGEEKLDRRIHYKKSDLIDYSPTTKPNAGENMTVGELCAAAVTLSDNTAANLLLASFGGP +EAITTFCRSIGDEITRLDRTEPTLNYDTPNDERDTTTASAMLENLQRLLFTDVLTPASRS +QLAAWLITNKTGDARLRAGLPKDWLVGDKTGTNGHGNANDIAVLWPTKRAPIIVTAYCEI +PAIAADERNAIIAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI000368AAFB +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. S-62 TaxID=2653123 RepID=A0A5J4LXK3_9RHIZ +----EAQLAALESKHPGRICVSILDLARGKRI-EHRAGERILMCSTFKALAAALVLARVD +KGDEKLDRRIHYKKSDLVDYSPATEPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP +EAITTFCRSMGDEITRLDRTEPTLNYDTPTDERDTTTASAMLENLRRLLFTDILTAASRS +QLAAWLITNKTGDTRLRAGLPKDWLVGDKTGTNGYGNANDIAVLWPSKHAPIIVTAYCEI +PAIAADERNAIIAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00048A8D4A +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium yuanmingense TaxID=108015 RepID=UPI0004BB555A +-----SEFESYERESGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAANVLARVD +RGEEQLAAMIPYGQADLLEYAPVARENLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSIGDTTSRLDHNEPELNRSQPGDPRDTTTPAAMAGNLRRLVTGEALSPASRV +LLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYTQG +GTPSAAQIASAFARIGRMVAE-- +>[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000672211F +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIL--- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9002 TaxID=2184558 RepID=UPI000F5E27BA +---ALDSIRSLEMSRGGRLGVAVLDTGSGRRL-QYRADESFAMCSTHKFLSAVAVLSLVD +QGKLALDKPVKYGNADLLDYAPVAREHVERGMTVDELCAAATVWSDNTAANLLLELLGGP +AGWTRFARSIGDDASRLDRTEPALNSAIPGDPRDTTTPDAMLANLKMTLLGTVLSESSRE +KLQSWMLSGTITDTLLRAGVPLEWRVGDKSGAGKNGTRNDIGIIFPPDASPILAAIYYTE +STGSLASREEVIAEVGGIIAETf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces rapamycinicus (strain ATCC 29253 / DSM 41530 / NRRL 5491 / AYB-994) TaxID=1343740 RepID=A0A0A0NSI4_STRRN +--AVTGEFKKLERSYDAHLGVYAIDTGTGHEV-AYRDGERFAFASTFKALAAGAVLRKYK +--LSGLDRVIRYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGV +KGLDATLEKLGDDVIQMERIEPELSRWVPGETHDTTTPRAMAKDLRAFVLGDVLDKGERA +QLTKWLRTNTTGDELIRAGMPKGWQVGDKTGSGSYGARNDIAVVWRPDAAPLVMAIMSYR +GDKDTPFDNKLIADAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsaceae bacterium YIM 96095 TaxID=2487137 RepID=A0A3N0EGJ2_9ACTN +---YAAEFERLEQEFDARLGVYARDTGTDAEV-THRADERFAYASTFKPLACAAVLERRS +--MAEMEETVTFGSEELVEYSPITEERVDTGMTLVEVCDAALRHSDNTAANLLFAELGGP +EGLQEALEELGDDVTRVEREETALNEAEPGDIRDTTTPEAFAANLEKYVLGDTLPEGKRA +LLREMMVGNTTGDDLIRAGVPEEWEVGDKTGSPGYGGRNDIAVVWPADGEPIVLAVMSSR +DEEDAEYDDALVAEATEVAVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. BK463 TaxID=2587008 RepID=UPI000DE17B72 +----EAQLAALESKHPGRICVSILDMASGKRI-EHRAGERILMCSTFKALAAALVLARVD +QGEEKLDRRIHYRKSDLIDYSPATEPNAGENMTVGDLCAAAVTLSDNTAANLLLASFGGP +EAITTFCRSIGDEITRLDRTEPTLNYDTPNDERDTTTASAMLESLRQLLFTDVLTPASRS +QLAAWLITNKTGDTRLRAGLPKNWLVGDKTGTNGAGNANDIAVLWPANRAPIIVTAYCEI +PEIAADERNAIIAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Edaphobacter aggregans TaxID=570835 RepID=UPI0005594BBB +--DLAATLAALEQKSKGRLGVAIL-FPDGRRA-TYRADERFPMCSTFKFLAAALTLQRVD +QNKERLNRTITYSKSDLVTYSPETEKH--TSMTVASLCQASLTLSDNTAANLLLASFGGP +PAITAFARSLGDPVTRLDRTETTLNESTPGDPRDTTTPTAMLANLQKILFGNVLKPASRD +HLTRWMLANTTGKAKFVAGLPATWKVADKTGSGDHGSNNDIGVLYPPGDKPILITSYLTE +TTITTDERNAIHADVARSITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. KKS102 TaxID=358220 RepID=K0HTM3_9BURK +--AWNEALASIERTAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD +QGKERLDARVHYAAADVVAYSPVSGARAGDGLTVGELCAATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDPITRLDRTEPTLNEAAVGDPRDTTTPLAMLQTLQKLVLGNALSPMSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPQGGAPMLVTCYLTR +STASGEQRDAAIAQVARAVAT-- +>[subseq from] Beta-lactamase n=1 Tax=Leifsonia sp. ku-ls TaxID=2220072 RepID=A0A3D8N7T2_9MICO +-----AALRGLEETYDATLGVYAVDTSTGRAV-GYRADERFAYASTSKALLAGAVLASVD +--DADLDATVRYTADDLVSYSPVTEGHVGEGMPLRDVIAAALRSSDNTAANLLFRQLGGP +DGLQRALRALGDTTTTVAREEPDLNEATPGDDRDTSTPRALAAALRSYAVGDALSPERRR +LLLDDMTGNATGAALIRTGVPADWTVADKSGAAAYGTRNDVAVVQPPGGAPIVLVVMSRK +QAKDAAYDNALIADAARAVATAf +>[subseq from] Class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=A0A2A2MNL3_9VIBR +-dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDRFPMMSTFKTLMCANALYLAE +QKKLNLNATTKVKESDLVTWSPITEKLTGQEITVQKACEATMLMSDNTAANIVLYQIGGP +EQVTQFIRSLDDKVTRLDRYEPELNQAIPGDKRDTTSPSAMVELLNTLLLQDGLNQESQR +QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPIILSIYLTQ +TQLDMAQRNRVINRVANLVFEQf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces nanshensis TaxID=518642 RepID=A0A1E7LYQ6_9ACTN +---TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLSGAVLARKS +--LPQMERLVRYGQEEIISHSPITGKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP +RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA +LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR +DVKDAEPDDALIAGAAEVALEAf +>[subseq from] Beta-lactamase n=1 Tax=Kushneria marisflavi TaxID=157779 RepID=A0A240US94_9GAMM +-qEVQGSIQALEQQHGGRLGVALMNVGTGAVV-SHRGNERFLFNSTGKVFIAAAVLAQVD +DGKASLDQRIEVKSSDLTGWTPITEQQLGSPMTIAELCQAAVAWSDNAAANLLIERLGGP +EHVTAFLRAIGDTTTRLDRTEPALNEDHEGDERDTTTPLAMMQTLRTLLLGEALSPASRH +QLAAWMIEGKTGDARLRAGMPTGWLVGEKTGTNSVGNAADIGIAWPSNRGAVIAIAYVYL +PQADKAQRDQVIAEIGQLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=UPI000C168BE6 +-dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHSDDRFPMMSTFKTLMCANVLHLAE +QKKLNLNATTTIKESDLATWSPITEKLTGQEITVQKACEATMLMSDNTAANIVLHQIGGP +EQVTQFVRSLDDSVTRLDRFEPELNQATPGDKRDTTSPSAMVELLNTLLLQDGLSSESQQ +RLLTWMKNNKVSDPLIRSVLPQDWSVADRSGAGNQGSRGITALVWNSQRKPVILSIYLTQ +TQLDMVQRNRVINRVANLVFEQf +>[subseq from] class A beta-lactamase n=1 Tax=Roseovarius tolerans TaxID=74031 RepID=UPI0009F6BE6A +-dDLRQTVQDVEARIGGRIGYAVTDLNGGQEW-GSRPDERFPMSSTFKALLCGVILARVD +AGAEALDRRITFGRDDLVTYSPVTDWHLGTGMTVGELCHAAITMSDNTAGNLLLATIGGP +EGFTEILRDMGDATTRLDRWETALNEGAPGDERHTTTPRAALSTLQALLFGDMLTVASRE +QLSDWMIADAVADDLLRASLPEGWIIGDKSGAGGHGSRSIIAVVWPTPNHPVLVTIFMTG +ADAGMTDRNAAIAEIGAAIFA-- +>[subseq from] Beta-lactamase n=2 Tax=Nocardioides sp. SLBN-35 TaxID=512030 RepID=H0BW75_9BURK +--EWNETLAHIERTAQGRLGVAMLDMGSGLQL-GWRQDERFAMASTFKAVLAGWMLALVD +QGRERLDARVHYAVADVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDSITRLDRTEPTLNEAAVGDPRDTTTPLAMLQTLQKLVLGDVLTPPSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVMWPPGGAPVLVTCYLTR +STAKPEQRDAAIAEVARAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia alba TaxID=225051 RepID=A0A4R1FYY6_9NOCA +----SATFADLESKYGARLGLSVLDTGSGAAL-AYRADERFPMASTFKGLACGALLQAHP +LSTGYFDQVIRYTPADLVVNSSETGKHLDTGMTVAALCDAAITLSDNTAGNMLLRLLGGP +AGFTAFLRTLGDPVSRLDRWEPELNTAIPGDERDTTTAAALVANYRALVVGTALPEPERA +QLATWLKASKTGATRIKAGLPADWIVGDKTGSPAYGSALDVAVAWPPNRAPLVLAVLTTK +PKRDAEPANDLVAEATEVAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura mexicana TaxID=134959 RepID=A0A238WSL4_9ACTN +--KVTRQIGRLEATHHLRIGAFAIDTGNGRKV-SNRPDERFAFASTFKAMACGAVLRKAR +RDPGLLDRVIHYTKDDLVDFSPVTEKHVDTGMTVAALCHAAITRSDNTAGNLVLKQIGGP +AGLTAFFRSIGDTVSRSDRWETALNDWKPGEPRDTTAPRPWAGDLRALTVGDALVPADRK +QLIGWMKATVTGDKRIRAGLPKNWTVGDKTGTGDYGTANDIAIAWPPSGAPLVIVITTNR +FGVDDEADDEAVAQTARVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BEB6DE9 +-------------------GIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. KKS102 TaxID=358220 RepID=UPI0005BCFA2F +--AWNEALASIERTAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD +QGKERLDARVHYAAADVVAYSPVSGARAGDGLTVGELCAATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDPITRLDRTEPTLNEAAVGDPRDTTTPLAMLQTLQKLVLGNALSPMSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPQGGAPMLVTCYLTR +STASGEQRDAAIAQVARAVAT-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces radiopugnans TaxID=403935 RepID=A0A1H9DHD0_9ACTN +-----RDLRSLEREFDARLGVYAVDTGTGREV-AYNDDERFAYASTFKALAAGAVLRKYS +--PSGMEEVVEYSEDDLVAHSPVTGKHTGTGMTLRELCEAAVRFSDNTAANLLFDAVGGP +RGLDTVLEEIGDDVTRMERREPELSRWAPGETRDTSTPRAFAGNLRAFVLGDVLGEGERA +QLAEWLRTNVTGSGLIRAGMPRGWVVGDKTGTGGYGVRNDIAVVWPPAGAPIVVAIMSNR +DEEDAEHDDELIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus wratislaviensis TaxID=44752 RepID=UPI000F5708FF +-qSLDAKIDALEAQYATRIGVTAVDPASGAVY-NHRGDERFAMCSTFKAYASAAVLRKIE +DGSTSLDKTVVIEPGDLVENSPVTAAAVGTPMTLGQIAEAALTRSDNTAGNYLLREIGGP +QAITALARDLGDESTRLDRWETELNTALRGDPRDTTTPAGLAQGFRALLLGDALDAASRD +QLVDWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWSPDGSPVVLAVLTDS +LTEDAQGNNQAIADTTAAVIE-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000804E4A9 +----GRAFEALEKEYAARLGVYAVDTGTGTTV-AHRDGERFAYASTFKALAAGAVLRRYG +--LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGALCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAGLGDEVTRMVRRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALRGPERA +RLTQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +TAADADHDNTLIAKAASAAVT-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. DOA9 TaxID=1126627 RepID=A0A0S6ULY2_9BRAD +-----SEFESYERESGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAASVLARVD +RGEEQLAAMIPYGQADLLEYAPVAKENLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP +AALTTFWRSLGDTTSRLDHNEPALNRSQPGDPRDTTTPAAMAGNLRRLVTGDALSPPSRA +LLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPETPILIAAYTQG +GTPSAAQIASAFARIGRMVAE-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces sp. SM8 TaxID=1195457 RepID=UPI000283062A +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +DAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAMTRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. YR519 TaxID=1500259 RepID=UPI0005682D1F +--DIDKRMGELEKQIGGRIGVSAIDTETNISF-GYRETESFALCSTFKVLAAGFVLSRVD +AGKENLERRVVYDKDKLITYSPETELHVGDEMSVGELCKAAITLSDNTAGNLLLESFGGP +KELTNWLRTIGDGSTRLDRWEPDLNEAKAGDPKDTTTPDAMLDTLGNITLGSVLTEPSQQ +KLAEWMVASTTGGARLRAGLPDSWKIGDKTGTGRNGSAADIAIIWPTGRGPILVTTYVAE +AKVPVAEINPVFAEVGKIVA--- +>[subseq from] Beta-lactamase n=2 Tax=Salmonella enterica I TaxID=59201 RepID=I1W5J4_SALET +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRGEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTDG +ES--------------------- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces jeddahensis TaxID=1716141 RepID=A0A177HLI8_9ACTN +----DGAFAELERTFDARLGVYAVDTGTGREV-AYRDRERFAYASTFKALAAGAVLRTYS +--LDGLDKVIKYSRKDLVDYSPVTERHVDTGMTVRALCEAALHYSDNTAGNLLLGMLGGP +KGLDAMLEGMGDDITRMQRRETQLNQWAPGSTPDTTTPRAFAGDLRAFVLGDVLGKAERT +QMADWLKANTTGAKLIRAGLPDDWVVGDKTGAGGFGTRNDIAVVWRPKAAPIVIAIMTNR +HTKDADYDNALIAKAASVVAR-- +>[subseq from] Beta-lactamase n=2 Tax=Acidovorax TaxID=12916 RepID=A0A2T6JEP1_9BURK +----KDTLAGIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD +QGKERLDARVHYAAADVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDEVTRLDRTEPTLNEAAVGDPRDTTTPLAMRQTMQKLVLGNALSPTSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPQGGAPVLVTCYLTR +SMASPEQRDAAIAQVARAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. LCT2 TaxID=2493093 RepID=UPI001373C1CB +------ELEAYERESGGRIGLYAENLATGAKI-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAVIPYGQADLLSYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRIDHNEPEVNKSAPGDPHDTTTPAAMAGNLRRLVTGEALSPASRA +QLTEWMVGCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWPKPDAPILIAAYTQG +GSPTAPQIEAVFARIGRMVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. 11515TR TaxID=2028343 RepID=A0A248WC62_9RHIZ +----ETQLAALESRHPGRICVSILDMGSGKRI-EHRAGERILMCSTFKALAAALVLARVD +KGDEKLDRRIHYKKGDLIDYSPATEPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP +KAVTAFCRSLGDDLTRLDRTEPTLNYDTPDDQRDTTTASAMLENLRRLLFTDVLTAASRS +QLAAWLITNKTGDARLRAGLPKDWLVGDKTGTNGAGNANDIAVLWPASRAPIIVTAYCEI +PEITADERNAVIAEIGRIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 74 TaxID=1827608 RepID=UPI000EABEE05 +--DTRARLRELEARHGARIGAFAYNLRTETTV-RHRAAERFPGCSVFKTLAAAAVLRDLD +QHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRHSDNTAANLLLRELGGP +TTITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFHAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PAQDAAADSPLVAATASVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. MJM8645 TaxID=1120523 RepID=UPI0007AFCE6E +--TTSASFKGLEQQFGARLGVYAVDTGSGREI-SYRSDERFAFASTIKSLAAGALLRKAS +--DAELDKVVAYRQEDVLSWAPITSQHVATGMKVRDLAAAAIQYSDNTAANLVMAELGGP +AAVQQSLRDLGDQTTSVDRNEPTLNEATPGDTRDTSTPSAFAADLRRYALGDVLAEDRRR +LLTDWLVGNTTGAPYIRAGVPTDWKVGDKTGNGGYGTRNDAAVAWPSGGSPVVIVVLSDR +GKADATSDDALIAQATKTVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. YK2 TaxID=1860096 RepID=UPI0009F4972E +----EAQLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD +KGDEKLDRRIHYKKSDLIDYSPATKPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP +EAITTFCRSIGDEITRLDRTEPTLNYDTPTDERDTTTASAMLENLRRFLFTDILTAASRS +QLAAWLIANKTGDTRLRAGLPKDWLVGDKTGTNGYGNANDIAVLWPSKRAPIIVTAYCEI +PTIAADERNAIIAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus siamensis TaxID=480071 RepID=UPI0009865DD2 +----HKDFDKLEKKYDADLGVYAIDTGTGETV-TYQANERFAYASTIKALTVGVLLQQKS +--ISDLKQRITYTRDDLVNYNPITKKHVNTGMTLNELCDAALRYSDNAAENLILKQIGGP +TGLKKALKKIGDEVTNPVYFEPKLNDVKPGETHDTSTPKALAISLKKFTLGDVLPTKERQ +LLTNWMKKNTTGDTLIRAGVPSQWEVADKTGSSDYGIQNDIGIIWPPKGEPIVLAILSHR +DEKDAASNDKLIAQATKKVINAf +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis thailandensis TaxID=589330 RepID=A0A229RVV1_9PSEU +--SAQADFEQLERAFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFTAGGVLQRTP +--VADLDRTVTYSQKDLVSNSPVTEKHVATGMPLRAVMDATLRYSDNTGGNLLFRELGGP +EGLNAVLRGIGDTTSHADRIEPELNDTFPGDKRDTSTPRALAVSLRAFALGDALPEDKRK +ILVDIMRANTTGDENIRAGVP-GWPVADKTGTAGYGTRNDIGVVWPPNRAPIVIAVLTDR +ADKDAKIDNKLLAQATAAAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003A236B9 +--DLHHEFRQLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRDIADAAVRYSDNTAGNLLLRHLGGP +ELFEQELKEIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD +ILNTWLRGNTTGAELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEPDASFDNALIAEATEVVIA-- +>[subseq from] Beta-lactamase n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=G2NGN1_STREK +---TAGAFEELEDKYDARLGVYALDTGTGREV-THRADERFAYVSTFKALLAGAVLRTYT +--VGGTDRLITYSGDDVVPDSPVAEKHVDTGMTLDALCDAAVRYSDNTAANLLLGQLGGP +EALNALLKRLGDDVTRMERLEPDLSRWDPDSTRDTSTPRAFAENLRAFVLGDVLGDAERA +RLTHWLRTNTTGDEVIRAGVPKGWTVGDKTGTGGYGVRNDIAVLWPPDRAPVVVAVMTSR +DREDDTHDNRLLAEAASVVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD5832A +--DIDKRMGELEKQIGGRIGVSAIDTETNISF-GYRETESFALCSTFKVLAAGFVLSRVD +AGKENLERRVVYDKDKLITYSPETELHVGDEMSVGELCKAAITLSDNTAGNLLLESFGGP +KELTNWLRTIGDGSTRLDRWEPDLNEAKAGDPKDTTTPDAMLDTLGNIALGSVLTEPSQQ +KLAEWMVASTTGGARLRAGLPDSWKIGDKTGTGRNGSAADIAIIWPTGRGPILVTTYVAE +AKVPVAEINPVFAEVGKIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Amphibacillus jilinensis TaxID=1216008 RepID=UPI000310B3E9 +--TVEETFSQLEEEYDARLGVYALDTGTGKTV-TYRSDERFIYASTHKPLSVGVLLQQKS +--IEDLDERITYSSEDLVNYNPITENHIDSGLTLKELSDASIRYSDNTAANLIFHEIGGP +EGFKEGLRAIGDNVTEPERIEPELNDVEPGDIQDTSTPEALAKSLQQFTLGDALPDDKQA +LLIDWLKRNTTGDALIRAGVPEGWEVGDKTGSGSYGTRNDIGIIWPPDRDPIILSVLTSK +EERDAEHDDALIARATEEVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus sp. CFH 90083 TaxID=2592336 RepID=UPI00128DDE60 +--QSEEAFKALEEEFDARLGVYAIDTGSEQTV-TYRSDERFAYASTFKALAAGAILQTKS +--MEELEEVITYSEEELVAHSPVTEKHVDSGMTWKEICEAAVRYSDNTAANLMLEELGGP +DGMEEILRENGDETIEMDRMETELNEAVPGDTRDTSTPQALAESLQTYVLSDLLPEDKRE +VLMDWITGNKTGDTLIRAGVPEDWEVGDKSGAGGYGTRNDIAVVWPSDNAPIVIAILSSR +DTADADYHDVLIERAAEQVIEQ- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. S-93 TaxID=2653122 RepID=UPI0012608BB7 +----EAQLATLESKHPGRICVSILDTASGRRI-EHRAGERILMCSTFKALAAALVLARVD +KGEEKLDRRVHYRTSDLIDYSPATEPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP +KAMTAFCRSLGDDLTRLDRTEPTLNYDTPDDQRDTTTASAMLENLRRLLFTDALTPASRS +QLAAWLITNKTGDARLRAGLPKGWLVGDKTGTNGAGNANDIAVLWPANRAPIIVTAYCEI +PEIAADERNAIIAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. A134 TaxID=2681970 RepID=UPI0012EDCA4C +---TDEVFTQLENEFDARIGVYAIDTGSNQTI-EYRPDERFAFASTYKALAAAILLQQNS +--LEELKEVITYTEDDLVTYSPITEKHVDTGITLLELSEAAVRFSDNTAGNLLFEALGGP +KGFEQALREIGDHVTKADRFEPDLNNYTPEDTRDTSTPRALATSFQAFAVGDLLSDNKHE +LFTDWLKGNATGDTLIRAGAPEGWEVGDKSGAAGYGTRNDIAIVWSPNREPIVIAILSRH +NTEDAEYDDTLISQAAEIALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. SYSU K10002 TaxID=2144174 RepID=UPI000D697FFF +-----SAFAELESKAGARLGVYAVDTGDGRVV-AYREGERFPMASTFKGLACGALLRDHP +LSSGFFDQVIHYTASEIVDASPETSKHVDTGMTVAALCEAAITLSDNTAGNQLLKLLGGP +EGFTAFLRSIGDTTSRLDRWETELNTAIPGDDRDTTTAAALTADYRALVVGDVLAAPERE +RLTSWLIANTTGGKRIRAGLPAEWRVGDKTGSPAYGSALDVAVTWPPGRAPLVITVLTTK +SEQQATADNALVAEATRVTL--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces davaonensis TaxID=348043 RepID=UPI000996BB69 +----TARLRALEEEHGGRLGVYAHNLATRRTV-RHRADELFPMCSLFKTLAAAAVLRDLD +RDGEVLNSRLHYTEADLVDVPDVIREHLSDGMTVAALAELAITHSDNTAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWEPELNTAEPWRVTDTTSPAAIGRTYGRLVLGDALNRRDRE +QLTEWLLRNTTSTARFRAGLPPAWTLGDKTGSGSYGTANDVGVAWTETGAPIVLSVLTTK +PEQNAAWDNALVAKTAKVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. 106 TaxID=2135637 RepID=UPI000EB4302E +-qQWQQALAQIEQKAQGRLGAALLDTGSGLAL-GWRQDERFAMCSTFKLPLAGWMLALVD +QGKERLDARVQYPASEVVDYSPVSGPKAGAGLTVGELCSATVSLSDNTAANLLLARQGGP +SALTAYLRTLGDTATRLDRNEPTLNEAAVGDPRDTTTPQAMLQTMQKLVLGDALTPASRA +TLQRWLVETSTGDKRLRAGAP-GWRVGDKTGTAGSGTTNDIGVLWPQGGAPVLLTCYLTQ +SKAKPEQREAAIAEVARSAL--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas hyacinthi TaxID=56455 RepID=A0A2S7ET11_9XANT +--TLAQRLAGIERRTAGRLGVTLLD-GNGAVLgGQRQDERFPMCSTFKFVLAAAVLQRVD +RGELRLQQPVQIRAADMLPHAPVTARHVGGALSVAELCRATMIFSDNPAANLLFPLVGDP +PGLTRFLRGLGDTQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRALLLGDALRPASRQ +RLTAWMLDNRTGDACLRAGLPRGWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLSAYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia thailandica TaxID=257275 RepID=UPI0006939340 +-------FARLETEHGARLGVFAVDTGSGRTV-AYRPDERFPIASTFKGLACGALLDEHP +LSSGWFDQRITYGADELVANSPVTAQHVDTGMTVAELCHAAITASDNTAGNQILELLGGP +AGFTARLRTLGDQVTRLDRWETELNTAIPGDDRDTTTAAALAADYRALAVGDALAEPERA +QLNSWLLASTTGAARIKAGLPADWRVGDKTGTPAYGSALDVAVAWPPGRAPLVIAVLTTK +PQADAEPDNALVAAAARE----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces koyangensis TaxID=188770 RepID=A0A385DJT4_9ACTN +------ALRTLERKYDARLGVYALDTGTGKTI-GHRADERFAFCSTFKTLAVAALLDRNP +--PGHLDERVTYTRGDINSISPVTRENVDKGMTVGQLCDAAIRYSDGTAANLLLRDLGGP +ERLTDYLRELGDTVSRLDHYEPELHQVRPGDPADTTTPRAIAADYRTVILGDTLARDQRA +LLTDLLERNKTGGNRIRAGVPKGWRVADKTGTGQYGRANDIAIVWPPASGPLVLAIMSER +SGREARPSEPLIAEATEHVT--- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. 106 TaxID=2135637 RepID=A0A497VCE0_9BURK +-qQWQQALAQIEQKAQGRLGAALLDTGSGLAL-GWRQDERFAMCSTFKLPLAGWMLALVD +QGKERLDARVQYPASEVVDYSPVSGPKAGAGLTVGELCSATVSLSDNTAANLLLARQGGP +SALTAYLRTLGDTATRLDRNEPTLNEAAVGDPRDTTTPQAMLQTMQKLVLGDALTPASRA +TLQRWLVETSTGDKRLRAGAP-GWRVGDKTGTAGSGTTNDIGVLWPQGGAPVLLTCYLTQ +SKAKPEQREAAIAEVARSAL--- +>[subseq from] Beta-lactamase n=2 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=R4T2H2_9PSEU +--QFHDRLLELENKFDARLGVYALDTEGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP +--LSHLETRVSYSRADLMKHAPVTERHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +AALTAFTRGLGDTVTRMDRIEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTADKRD +FLRDLLQRTVTGAGRIRAGLPHGWTIAGKTGTGEYGTLNDIAVLWPPGKAPIVLAVMSSK +AAKDAPYDEALLAEAARYVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces pseudogriseolus TaxID=36817 RepID=UPI000A3C5D47 +------RLRALEREFGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDRRP +--GARLDERVSYSTADLVTYSPVTEKHTADGMTLRQLCDAAVRYSDNTAGNLLLRDIGGP +GGLTAYARRLGDRVTRLDHVEPELNSNPPGDPRDTTSPRAIAADYRALVLGDALPAAGRA +LITDWLVRNTTGDRRIRAAVPRGWRVGDKTGGGEWGRGNDVAVLWPGGRPPLVLSVLTER +TDRAASPSDELVAEAARRVLD-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013D91A24 +----ASDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFDVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMGGSLQRVVLGKVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +SAISNEQRAQVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora azatica TaxID=58347 RepID=UPI00055B9813 +----TGRLRALEQAHSARLGVFACNTVTGRTV-LHRADELFPMCSTFKTIAAAAVLRDLD +RDGEFLATRIRYTQQEVTRYAPITGQNLAGGMTVADLCAAAIEHSDNTAANLLLRELGGP +GAVTRFCRSIADDVTRLDRWEPELNSAEPERVTDTSSPRALARTCARLTLGTALEPRDRE +RLTGWLLANTTGGNRLRAGLPNGWTVADKTGTGGYGTTNDVGIAWPPDHGPIVIAILATT +QHAATPADEPLLAATAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces bicolor TaxID=66874 RepID=UPI0004E0C879 +haTTTDRLHDLEQRHGARLGVFAHNLATGRTV-RHRADERFPICSLFKTLAAAAVLRDLD +RDGEVLAKRIHYTQDDLVANSDETAKHLATGMTVAELADVAIRFSDNTAGNLLLRELGGP +TAVTRFARSLGDPVTRLDRWETDLNSAEPWRVTDTTSPRAIARTYARLVLFDALNRPDRD +LLTHWLLNNTTSANRFRAGLPKTWTVADKTGGGSYGANNDVGIAWTEDGTPLVLAVQTTR +PDQDAALDHALIVETAALIA--- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. CNZ279 TaxID=2035251 RepID=A0A2G7E2G5_9ACTN +--EVAAAFKKLERKYDARLGVHAVDTGSNQEI-SYHADERFAYASTHKAFTAAAILDKHS +--LSGLDKVITYKKKDLLPHSPVTSKHVDEGMTLRALCAATVRYSDNAADNLLLRELGGP +KALDAFLEDLGDDVTHANRYEQELNEATPGDKRDTTTPRAFAEDLRAVALGDALDKKERA +QLSTWMRESPTGKTLINAGFPKDWTVADKSGAGRYASRNDIAVVRPPGKAPLVVTVMSKR +SEQDADYDDKLVSEAASVVADE- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000DAD0900 +---TAGAFEKLEDKYDARLGVYALDTGTGREV-THRADERFAYVSTFKALLAGAVLRTYT +--VGGTDRLITYSGDDVVPDSPVAEKHVDTGMTLDALCDAAVRYSDNTAANLLLGQLGGP +EALNALLKRLGDDVTRMERLEPDLSRWDPDSTRDTSTPRAFAENLRAFVLGDVLGDAERA +RLTHWLRTNTTGDEVIRAGVPKGWTVGDKTGTGGYGVRNDIAVLWPPDRAPVVVAVMTSR +DREDDTHDNRLLAEAASVVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Labrenzia sp. EL143 TaxID=2073157 RepID=UPI000CF0CEBB +---VAKAIEDIETRLSARVGVSIIDTESGKTW-SHKGDERFPMNSTFKAFLCAALLDAAS +NGTVDAGREVVVEESDIVSYSPVTAKRVGGAFTIEDLCRVTVTISDNAAANIVMKEVGGP +EGVTAYLRGIGDDISRVDRWEPESNTGIPGDDRDTTTPDAAAETLRKLVLDETLAADARA +KLTGWLEGNKVGNSTLRAGLPEGWRIADKTGAGANGSRNNIAVIWPEGRKPLVIAIYITQ +TTAAFEARNKAIAGIAQAL---- +>[subseq from] Beta-lactamase n=1 Tax=Roseovarius tolerans TaxID=74031 RepID=A0A1H8DDN4_9RHOB +-dDLRQTVQDVEARIGGRIGYAVTDLNGGQEW-GSRPDERFPMSSTFKALLCGVILARVD +AGAEALDRRITFGRDDLVTYSPVTDWHLGTGMTVGELCHAAITMSDNTAGNLLLATIGGP +EGFTEILRDMGDATTRLDRWETALNEGAPGDERHTTTPRAALSTLQALLFGDMLTVASRE +QLSDWMIADAVADDLLRASLPEGWIIGDKSGAGGHGSRSIIAVVWPTPNHPVLVTIFMTG +ADAGMTDRNAAIAEIGAAIFA-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000477609B +--DLSHEFRQLEERFDARLGIYAVDTGAGRTV-RYQANERFAYGSTFKALAAAEVLDATT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAVADAAVRYSDNTAGNLLLRHLGGP +ERFEQELKGIGDNVTDAARYETELNEAAPGDPRDTSTARALAEDLREYAVDDALEPTDRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEKDASHDNALIAQATEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseus TaxID=1911 RepID=UPI0004C57668 +----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLGKYS +--LDGLDRRVTYTRKDLVANSPVTEKHVGTGMTLKELCDASVRYSDNTAANLLFDHVGGP +RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAVDLRAFVLGGALPAPERE +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR +ATKDAEPSDELIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. b94 TaxID=1827634 RepID=UPI000D1A55E1 +----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLGKYS +--LDGLDRRVAYTRKDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +RGLDASLEKLGDHVTRMDRVEPKLSRWVPGEKRDTSTPRALAGDLRAFVLGEALPAPERE +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR +ATKDAEPSDELIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces resistomycificus TaxID=67356 RepID=A0A0L8LJZ6_9ACTN +--ATARAFRDLEGEFDARLGVYALDTGTGRTV-AHQADERFAYASTFKALAAGAVLRKFG +--TDGIDKVVTYARDDLVENSPVTDDFVETGMSLRELCAATLWYSDNTAVNLLLHELGGP +DGLEKVLEQLGDHVTEMDRYEPEMSDGTPGDSRDTSTPRAMAAGLRAFLLGDALGREERD +LLRQWMETNTTGETLVRAGLPADWKVADKSGSAGYGGRNDIAVVWPDDGNPIVMAVMSSR +DKQGAERRDALIAKAATVAID-- +>[subseq from] Beta-lactamase n=2 Tax=Desulfovibrio sp. X2 TaxID=941449 RepID=S7TJZ6_9DELT +--RLAEAVQNEEAALHARIGMAVSDTNGGDVW-QYRGDERFPLNSTHKVFACAALLARVD +AGVLAPDRRVSITESMLVVYSPITKKHLAPEMTLSEVCRASVSYSDNTAGNVVVDAAGGP +AAVTAFMRSIGDGVTRLDRAEPELNEAAPGDPRDTTTPAAAAASLARVVLGDALAPSSRA +ALTDWMLHDQVADGLLRAALPPDWRIADKTGSGGHGSRSILAVVWPPKRSPLVVAIYITQ +TEASVQDANLAIARIGRVL---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5126 TaxID=1463857 RepID=UPI0004C57A4D +--ALDRKLAALEKRYHAHVGLYVLDTKTGRTV-SYHADRRFAHCSTIKALAAGVLLKRTS +--DARLDHVITYRKADLVSYSPITSKHVAHGMTLRAVITAALEYSDNTAENLMLAQLGGP +ESLESALRKMGDATTNADRTEPSLNDATPGDTRDTSTPRALGTDLRAFLLGDALPAGRRS +MLRNWMVHNTTGTDYIRAGVPAGWKVGDKTGSGGYGTRNDIAIAWPPARGPVVISVLTDR +GTANAPSGDALIADATRTAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces lavendulae TaxID=1914 RepID=UPI0010085999 +---TDRAFAELERTFDARLGVYAVDTGDGRTI-AHRPDERFAYASTCKALLAGAVLAKKT +--LPQMERLVRYGKEEIISNSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP +RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYTLGTALPAEKRA +VLIDWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVWPPGGAPIALAVLSRR +DIKNAETDDALIAGAAKVALGAf +>[subseq from] Beta-lactamase n=1 Tax=Roseomonas nepalensis TaxID=1854500 RepID=A0A502FRP4_9PROT +----EAAVRAAEREAGGRLGVAVLDTGTGARA-AWRGGERFPVASTFKLLLAAAVLQRVE +AGREGLDRRVPIAAADLVDHAPVTGRRVGPEMSVRELLEATMVWSDNPAANLLLPSVGGP +EGLTRAARGWGDEGFRLDRWETALGEGRPGDPRDTTTPAAMLLSLERLLVGEVLSGPMRD +LLVGWMVGSRTGDAKIRAGLPPGWACGDKTGAAGHGTSNDVAVVWPPGRAPVLVAAYLTE +SPAAPAGRDAALAAVGRAVAAGf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 1331.2 TaxID=1938835 RepID=A0A285QAY0_9ACTN +--DTHRRLSALEQQHGARLGVFARNLSTGRTV-RYRAGELFPICSVFKTVAVAAVLRDLD +RDGEFLAKRIHYTEADIKRGAPVTGENLANGMTVAELCKAAIDHSDNTAGNLLLRELGGP +TAVTDFCRSIGDHVTRLDRWEPELNTAEPDRTTDTTSPQAIARTYRRLTLGHALPPAKRD +QLTTWLRGNTTSIHRFREGLPQDWALADKTGSGQYGTANDVGIAWTPSGAPVVLAVLTTK +PDEAAPKDEPLVAETAALLA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB43_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPSLLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMATTLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobiales bacterium 35-68-8 TaxID=1970552 RepID=A0A258M2C0_9RHIZ +--------GPLEAKTGGRLGICVLDGAGGIIA-AHRAQERFAMCSTFKLLLAAAVLARVD +EGRERLDRRITYTAADPVGHSPVTRQNVADGMTVGELCAATVALSDNGAANLLLATLGGP +EGLTAFLRRTGDTVTRLDRWELALNSAIPGDPRDTSTPAAMAGSIRRLVAGTVLKPASRT +QLRDWLVATKTGDTRLRAGLP-GWHVGDKTGTGNNGTVNDVGFALAPGADPIVIAVFLTK +SRLDVEASSAIIADVARQVA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium forestalis TaxID=1419263 RepID=A0A2M8QY19_9BRAD +------ELETCERNSGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAATIAYDKADLLDYTPVAKQNLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGNPQDTTTPAAMANNLRRLVLGEALSAQSRV +QLTDWMVNCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYTQG +GTPTAEQIAAAFARIGRIVAD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=D2KB72_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALXGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Pigmentiphaga sp. D-2 TaxID=1002116 RepID=UPI00104419F4 +--AALDELARLERLAQGRLGVSVVDTATGEEF-GRRADERFQMLSTFKLLAASFVLARHD +RGEDSLDRRIRYERDDLVRWSPVTEKHVGGHMSLAELCHATLTTSDNTAANLILRSFGGP +EALTRFIRSLGDNVTRCDRYEPELNVPHATGLLDTTTPHAITRTMGKLTVGEALSPASRE +RLQSWLVGNTTGDKRLRAGVPAGWRIGEKTGTYSKVGANDIGLAWPPGRPAILMSVYVAS +TRAADEVKDQVIAKVAELVG--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces cattleya (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057) TaxID=1003195 RepID=F8JTX3_STREN +-----AKFAALERKYAARLGVYAVATGTGTTV-TYRADERFAFCSTFKTLAAAAVLHRNP +--LSYLDKRVTIHAADVNSISPVTEDRVDTGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP +AGLTAYLRGLGDTVSRMDHYEPELNRNPPRDPRDTTTPEALAGDYRALVLGNALPAEKRA +LLKGWLQHNTTGAERIRAALPAGWTVADKTGTGDYGRANDVAIAWPPHTAPVVVAVMTER +SGYHTPAEDPLLADATRQIL--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. A0642 TaxID=2563100 RepID=A0A4S2USQ2_9ACTN +----ERAFVELERKSDARLGVYALDTVSGRAV-AHRSDERFAYASTCKALLAGAVLGRNS +--LRQMDRLVRYGRDDLVTNSPVTEQHLATGLTLRELCDAAVRYSDNAAANLLFRELGGP +RALQAALRAQGDRTTRCDRYETALSDAVPGDVRDTSTPRALAGDLRAYVLGTALPADKRA +VLTDWLKRNTTGDHTIRAGTPDGWQVADKTGTGGYGTRNDIAVVWPPHATPVVLAVLSRR +DAEDAEHDDALIAHAAEIAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SM11 TaxID=565557 RepID=UPI000CD5A4E5 +-----RAFVALEKEYAARLGVYAVDTGTGRAI-AHRDGERFAYASTFKALAAGAVLREYG +--LGGLERVVAYRREDLVEHSPVTEKHVATGMSLGDLCDAAVRHSDNTAGNLLFDAVGGP +RKLQAVLAELGDDVTRMVRRETELNEWSPGAVRDTSTPRAMAEDLRAFVLGDALGKPERA +RLTQWLRNNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPGAAPLVLAVLSNR +TEADAAFDNTLLARAASAAVS-- +>[subseq from] BKC/GPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=unclassified Shinella TaxID=2643062 RepID=UPI0006816CCF +-eDLAQRLAALEARHGGRIGVAIHNLSTGARL-GHNTDERFLMCSTFKALLAGHILARVD +RGEETLDRRIVVKKADLVDWSPVVETRVGGKISIAELCEATITFSDNAAANLLLAASGGP +EAVTAFLRGLGDAVTRLDRTEPTLNYETPDDVRDTTTPTAMVETLRRLVFADVLSARSKA +QLAAWLVMNKTGDARLRAGFPADWIAGDKTGTNGAGNANDVAIAWSPDRGAIIVAAFCEI +PGISGDERNAVIAEIGRIAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia grenadensis TaxID=931537 RepID=UPI0007A484B0 +--VTTQQFADLEAAHGARLGVFAVDTADGRSV-AYRDGERFPMASTFKGLACGALLHEHP +LSSGFFDRVIRYPRTDLVANSPVTEQHVDTGMTVAALCDAAITVSDNTAGNQILKLLDGP +AGFTAFLRTLGDDTSRLDRWETELNTAIPGDERDTTTAAALAADYRALVVGDTLAEPERA +QLAAWLVASATGGNRIRAGLPADWKVGNKTGSPAYGSALDVAVAWPPGRAPLVIAVLTTK +SEQDAEPANDLVAAATRAAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003782202 +--DLHHEFRQLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLRHLGGP +ELFEQELKEIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DAPDASYDNALIAEATEVVIA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A106H9I1_9BURK +---ALDSIRSLEMSRGGRLGVAVLDTGSGRRL-QYRADESFAMCSTHKFLSAVAVLSLVD +QGKLALDKPVKYGKADLLDYAPVAREHVGRGMTIDELCAAATVWSDNTAANLLIELLGGP +AGWTRFARSIGDNASRLDRTEPALNSAIPGDPRDTTTPDAMLANLQQTLLGTVLSDSSRG +RLQNWMLSGTITDTLLRAGVPLTWRVGDKSGAGRNGTRNDIGIIFPPHASPILAAIYYTE +STGSLASREEVIAEVGGIIAKTf +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. BK707 TaxID=2512160 RepID=A0A4Q7U3B3_9BRAD +------ELESYERDSGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGDEQLAAMISYGQADLLSYAPVAKENLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVTGEALSPASRT +QLTGWMVNCKTGANRLRGGLPAEWTIGDKTGNNGKDASGDIAVVWPKPDTPVVIAAYTQG +GTPTAAQIAAVFARIGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia carnea TaxID=37328 RepID=UPI0002F54A9A +-----AAFTDLETTHGARLGVFALDTGTGRSV-GHRMDERFPMASTFKGLACGGLLDRHR +LSSGFFDQVIHYPRHELVEYSPVTEQHVDTGMTVADLCHAAITVSDNTAGNQILKLLDGP +AGFTAFLRSLGDSTSRLDRWETELNTAIPGDERDTTTPAALAAGYRALVVGDRLPEPERE +QLRSWLVATTSGADRIRAGLPADWTVGHKTGTPAYGSALDVAVAWPPGRAPLVIAVLSTK +PEQDAEPDGALLAAATRIALS-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis halophila TaxID=141692 RepID=UPI00034D6A85 +-----AGFERLEEEFGARLGVYALDTGSGEEV-AYNADERFAYASTFKVPACGAVMEEHS +-LKEMEETVVHFDEEDLVTYSPITEDHVDTGMTLMEVCDAALRYSDNTAANLLLEEIGGP +EGFQEAMRELGDEVTVSSRWETELNENKPGDERDTSSPRAFAGNLEEYVLGDTLEEDKSE +ALADMMVRSTTGDTLIRAGVPEDWKVGDKSGMPGYGARNDIAVMWPPEGDPIVLAVYSTK +DTEDAESEDELIAQAAEEAV--- +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium AO1-B TaxID=1905358 RepID=A0A1L9QJ15_9PROT +---LSKAAKAIESRLNTRIGVAVFDPASGLNW-NYNGDDRFPMNSTMKAFACAALLDRVD +KKQSSLDQRTIITSDMIVSYSPVTEKHINTAMTLADHCEATITISDNTSANIILEELGGP +IGVTTYMRSIGDDVTRLDRYEPSLNEGTPGDPRDTTTPVAAAQSLYKVLFSDELSASSRK +HLMQWLEANKVGDATLRAGLPHDWRIGDKTGAGAYGSRGNIAIIWPPNHTPVALAVYVTE +NEAEFQARNKAIAEIGAAFK--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium symbiodeficiens TaxID=1404367 RepID=A0A2U8QJF4_9BRAD +------ELETYERESGGRIGVYAENLATGKKL-TWRADERFVMCSTFKASLAACVLARVD +RGEEKLAATIAYGKADLLEYAPVAKQKLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALTPASRA +LLTEWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVAWPKPETPILMAAYTQG +GTPNAAQIEAAFARIGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=UPI0005128BD7 +-dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDHFPMMSTFKTLMCANALYLAE +QKKLNLNATTTVKESDLVTWSPITEKLIGQEITVEKACEATMLMSDNTAANIVLYQIGGP +EQVTQFIRSLDDKVTRLDRYEPELNQAIPGDKRDTTSPSAMVELLNTLLLQDGLNQESQQ +QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPIILSIYLTQ +TQLDMAQRNHVINRVANLVFEQf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI13_KLEOX +--AIQQKLADLEKHSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE +SNPEVVNKRLEIKKADLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP +EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYL-- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. A244 TaxID=2137016 RepID=A0A2T4NGW6_9ACTN +----TARLRELEREHTARLGVYARNVRTGRTV-TYRADELFPMASVFKTLAAAAVLRDLD +RDGEFLARRIHYTQAYVIRFSPVTKDYVAAGMTIAELCDATIRFSDNTAGNLLLKELGGP +TAITRFARSIGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGGVLEPRDRA +RLTDWLLRNTTSLERFRKGLPADWLLADKTGGGQYGSNNDVGITWPPDGPPIVMSVLTTQ +PEEDAPADNPLVAGAAALLA--- +>[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus kozodoii TaxID=351676 RepID=A0A2D0LF04_9GAMM +---IIHQLAILEKNANGRLGVVLIDTSDHSTL-SYRANERFPLCSTSKLMAVSAILKKSE +TNAHLLNQRVHYQQSDLVEYSPITEKHLKEGMTLGELSAATLQYSDNTAMNLLLNQLNGP +NEVTLFARTLGDNSFRLDRYEPELNTAIPGDERDTSTPQAMAESLYDLVLGDALATAQRE +QLAKWIKGNTTGSASISAGVPQDWVVGDKTGRCDYGTTNDIAVIWPPKRAPLVLVTYFTQ +PDKEASARPDVLAAAARIVTQ-- +>[subseq from] Beta-lactamase n=1 Tax=Arenimonas composti TR7-09 = DSM 18010 TaxID=1121013 RepID=A0A091BCP3_9GAMM +----ANRIADLEERHGGRLGVAVLDTATGEGF-AWRAYERFPMCSTFKWLLAAQVLAAVD +AGEASLDRRLHWRREDLISGSPVVGKDPAAGLTVGELCAAAITTSDNTAANRLLAEFGGP +SGLTAWLRATGDESTRLDRNEPTLNLWRPGELRDTTTPMAMADSLRRILTGDVLSAASRA +QLIGWLLANTTGDSRLRAGLS-GWRVGDKTGTGNDGTSNDVAIAWPPDAAPILIAAYYCE +GGDDAAKRDAVLAEVGAIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium segetis TaxID=2488750 RepID=UPI0010514C19 +----RQSLRLIEDRLGGRLGVAVRDTGSGRAL-LHQADARFPLCSTFKVLAAAAILARVD +AGRERLERTMSYTAADLDSHAPATEAGRDSGMSLADLCAAAIVVSDNTAANLMLQALGGP +PALTAWLRGIGDGTTRLDRTEPTLNTAIPGDPRDTTSPAAMAEDLERLLIGDVLSPASRA +RLEGWMVAARTGLKRLRAGLPPDWAVGDKTGSGDNATANVVAILRPPHRAPLVAAIYLTG +SVSTAEERDAAHAEVGRLLAATf +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura echinospora TaxID=1992 RepID=A0A1H5T212_9ACTN +--EARRRLRELEDSYQGRIGAFAFDTGSGRIL-AHRAHERFPMLSTFKAVAAAAVLHKAR +RDPGLMDRIVRWSSEDLVDYSPITEQHVDTGLTVAQLCDAAIRYSDNTAGNLLLKQIGGP +PGLTRFLRSLGDPVSRLDRWETELNEWSAGERRDTTTPEAMGRDLHRLTVGNGLAEADRR +RLIGWLRGNTTGDKRIRAGLPEDWTVGDKTGTAGS-AANDVAIAWPPGSAPVIFAVYTAR +RDFDAPGDEQVIATTATILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia inohanensis TaxID=209246 RepID=UPI000A029155 +--AAESAMKGLEEKYGARLGVFAVDTKSGKEV-AYRSDERFAMASTFKGLACGALLKTYP +LSTGYFDQVIRFGREELVTYSPVTEQHVDSGMTVAELCQAAITMSDNTAGNLILRLQGGP +GEFTAFLRTLDDSVSRLDRWETELNANTPGDERDTTTPAAVAADYEKLVLGDTLGEPERE +LLKGWLIANTTGGQRIRAGVPQGWTVGDKTGAPEYGGNNDVAVAWTDKGVPVVIALLSTK +SAPDAKADNALLAEATRAVVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas carotinifaciens TaxID=1166323 RepID=UPI000DDB07D1 +---LADLAADLERRIGGRLGVAHFVPRTGMLH-GHRLEQRFPMCSTFKLLAVAAILARVD +GRRDHLDARVAVREADLVAHAPVTGPHIGGTMTLADLCAAAMRESDNVAANLLLRRLGGP +AGITAYAQSLGDRATRLDRWEPDLNSALPGDPRDTTTPAAMARLAGRILEGDSLRPPSRA +LLRRWMTQTRTGLTRIRAGLPHSWSVGDKTGSGANGTANDVAWFHPPGRDPAILAIFLTD +TQASAAARDAVFATIARHVA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces ossamyceticus TaxID=249581 RepID=A0A3N1LJD7_9ACTN +-------LRALEEQYGARLGVYAHNVRTGETV-RHRADTLFPICSLFKTLAAAAVLRDLD +RDGEVLSRRIHYTAADLLENSDVTRDHLATGMTIAELCDAAIRHSDNTAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRITDTTSPRAIGRTYARLVLGDALSRPDRA +LLTHWLLHNQTSNTRLRAGLPSSWAVADKTGGGSYGTNNNVGIAWTEDGTPLVLSIVSRK +FDRDAATDNKLIADTAHLL---- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003FAF381 +---LNHEFRQLEERFDARLGIYAVDTVTGRTV-RYRADERFAYGSTFKALAAAEVLDATT +--DAELDQVVRYSADDLVDYSPITEQYVAEGMTLRAIADAAVRYSDNTAGNLLLHHLGGP +ERFEQELRGIGDNVTDADRYETDLNEATPGDPRDTSTARVLAEDLREYAVDDALEPTDRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEPDASFDNALIAEATEVVIA-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Shinella TaxID=2643062 RepID=A0A4Y8QIP1_9RHIZ +--ALGKRLAELEARHKGRIGVAIHNLATGARL-GHRADERFLMCSTFKALLAGHILARVD +RGEETLDRRIVVKTSDLVDWSPVVEKHVGDAISVAALCEATITLSDNAAANLLLAVSGGP +EAVTAFLRGFGDTVTRLDRTEPTLNYDSPADERDTTTPAAMTDTLHRLVLGDVLSPQAKA +QLAAWLVMNKTGDTRLRAGFPANWMTGDKTGTNGAGNANDVAIAWSPDRGAIVVTAFVEM +PGISGDDRNAIIAEIGRVAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00039FB764 +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDHAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] Beta-lactamase n=2 Tax=Oceanobacillus picturae TaxID=171693 RepID=A0A0U9H5G1_9BACI +--KLDEEFASLEDDFDAQLSVYALDTGADQTI-AYRAEERFAFSSTYKALAAALLLEQNE +--MEELNEVITYTEDDLVPYSPVTEKHVDSGMTLLEIGEAAVRTSDNTAGNLLFEALGGP +AKFEEALREIGDDVTQSDRYETELNEFNPEDTRDTSTPKALATNLKKFAVGDLLTDEKRE +LFTDWLQGNATGDTLIRAGAPKGWVVSDKSGAGTYGTRNDIAVVWPPDREPIVMAIMSRH +DTEDADYDDALISEAAEVVFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces violaceoruber TaxID=1935 RepID=UPI0004C6B5F6 +-----GAFRQLEREFDARLGVYALDTGTGRSV-AYQADERFAYASTFKALAVGALLQRRG +--QAGLDKVLTYSQDDLVENSPVSENFVGTGMSLRELCAATLWYSDNTAANLLLEELGGP +DGLEKALERLGDDVTEMDRYEPDLSDGTPGDLRDTSTPRAIAGDLRAFLLGKALERDERA +LLRTWMETNTTGETLIRAGLPDDWTVADKSGSAGYGGRNDVAVVWPDDGDPVVLAVMSSR +DTQGAERRDALIAKAATVAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces decoyicus TaxID=249567 RepID=A0A0L8LU52_9ACTN +-----EALRRLEHTHRARVGAFAHNTATGATV-AYRAHTRVPLCSVFKPLAVAAVLRDLD +RNGETLARRIHYTDADLVENSPVTEKHVATGMTIAELCAAAVRRSDNTAGNLLLRELGGP +TAVTAFARSLGDRTTRLDRWETELNSAEPWRRTDTTSPAAIGRTYARLLVGDALSASDRG +RLTAWMKTNETNTERFRAALGKAWAIADKTGSGSYGTGNDVGVAWAPDGTPIVLAVLTGK +PEQAAAYDNPLIVDVTKVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. Huas11 TaxID=2183912 RepID=A0A495L6R6_9ACTN +----ELDFALLEEEFDATLGVYALDTGSGEAV-EYRADDRFAYCSTFKVPLFGVVLEQTT +--PEELEKEVPVSEDDLVNWDPIAEQHVGGTMSLYELGNAALRHSDNAAANLLLEELGGP +EALDAALEEIGDDVINVDRIEPDLSEGAPGDERDTSTPRAMATTLEAFTLGDVLPEDESE +TIVEMMRGNTTGDDLIRAGVPDDWEVGDKTGSGGYGTRNDIAVLWPPEGDPIVLAVMSTR +GQEGAEHDDALIAQATEVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000D112776 +--ETLVKVKDAEDQLGARVGYIELDLNCGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRLVVIYTT- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Labrenzia sp. PHM005 TaxID=2590016 RepID=A0A4Y6S284_9RHOB +---LQKAANEIENRLKTRIGIAVYDPENAIEW-DYNGDQRFPMNSTMKAFACATLLHQVD +TGKSDLGQPVAIEEDMIVKHSPVTKDHIGSSLTYADLCEATVTTSDNTAANLVLQELGGP +AGLTAFMRSVGDQITRLDRYEPTLNEGTPGDPRDTTTPRAAAETLYKLVFSNALSDASRN +KLAGWLEGNLVGDSTLRAGLPEGWRIGDKTGAGAYGSRGNIAIIWPPNRKPLALVVYLTE +NKAAFKVRNKAIAEVGAAFA--- +>[subseq from] class A beta-lactamase n=1 Tax=Kosakonia sacchari TaxID=1158459 RepID=UPI00031E383A +------AVARLEEHLGARIGIAVIDTASGETV-SYRGDERFPLNSTHKALLCGALLSKVD +KGELALNETTQFSQSELVAYSPVTSKFVAPSMSWQQLCSAAITESDNTAANLLAKKLGGP +AAVTRFFVDSGDSVTRLDRAEPELNSAVPGDLRDTTTPLAVSHTLQKLTLGEVLTPRSRA +QLVQWMKEDKVADALLRSTLPKGWVIGDKTGAGGYGSRSIISIVWPKKGAPRIVSIYITD +TKATIAQSNDAIARIGKAIFS-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. LMO-1 TaxID=2681549 RepID=UPI0012E8D4AE +---LRSRLAALEARSGGRLGVAVLDVRHGRID-GYRIGERFRMCSTFKALAAGFVLHRAD +RGEERLDRRIGYTSADLPDYSPVTEKHVASGMTMAELCHAAVTVSDNGAANLLLASFGGP +AALTAFLRRIGDRKTRLDRIEPALNSGAADDPRDTTSPAAMAATLRRLVLGDALSPASRA +RLGAWLVASTTGRTKLRAGIPAGWTVGDKTGSWGGGISNDVAILWPPGRPPMLIAAFLAA +PLVD-EARSAILADVARIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. AU4i TaxID=1335308 RepID=U2FU55_9BURK +----EMRLAQIEAQVGGRLGVAILDTASGKQV-GWRMYERFPMCSTFKILLASLVLMRTD +HGQEDLTRKIVFSKREVVPSSPVSGPRADSDMTIAELCEAALTHSDNTAGNLLLTSVGGP +TGLTAFARSIGDKFTRLDRNEPALNEAAEGDPRDSTTPAAILSDMHALLLGSTLSSSSRD +QLIAWLVSNKTGDARLRARLPKDWRIGDKTGTGDHGTVNDIAVVWPAGRAPVFVGAYLTG +ATATSTQRDEAIAKIGELVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB01580 TaxID=1703933 RepID=A0A1Q5GK15_9ACTN +---VASRLAQLEREHTARLGVYAHHTRTRRTV-AYRADERFPMCSLFKTIAAAAVLRDLD +HDGEFLAERIHYTRRYAEDYCPITGENIARGMTVGALCDAAIRHSDNAAGNLLLRELGGP +TAVTRFCRSTGDGRTRLDRWEPELNSAEPWRTTDTTTPRAIGRTYANLTLGDALSPRDRR +RLTGWLLGNTTSDERFRAGLPADWTVADKTGGGRYGGSNDVGITWPPGGAPIVMAVLTTR +YEEDAQADNALVARTASLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ICC1 TaxID=2099583 RepID=A0A2Z4VBJ8_9ACTN +--AVAQRLAELERAHSARLGVHAHDTATGRTV-GYRARERFPLCSVFKTLAVAAVLRDLD +RDGEFLAKRIRYTGQEVTGHTPITGKNLADGMTVGELSDAAIRFSDNAAANLLLRELGGP +TAVTRFARSIGDATTRLDRWEPELNTAEPWRITDTTTPHAIGRTYERLTLGTTLAPADRR +RLTDWLLGNTTGGERLRAGLPPAWAVADKTGGGAYGTNNDVAVAWPPGRPPLVIAVLTTR +SHRDAPADNLLIARTAEVVS--- +>[subseq from] Beta-lactamase n=1 Tax=Niveispirillum cyanobacteriorum TaxID=1612173 RepID=A0A2K9NK95_9PROT +---MREAMAALERARGGRLGVTLLDTKTGAAM-NWRGDERFAMCSTFKFLLAGYILSRVD +TGQERLDRLVTFGKHELVMWSPMTEPHVDKGMSIADLCQAIMIQSDNTGANVLMRESGGP +AALTAFLRATGDGVTRVDRIEPEMNVVGPGDVRDTTTPVSMLGLMRSLLLGDVLKPASRQ +LLIDWLIDNRTGKDRLRAGLPAGWRIGDKTGTYE-AFNNDIAILWPPAGGPLLLTSYYAN +PTADKAVRNIVHAEVAAIVAKAy +>[subseq from] class A beta-lactamase n=1 Tax=Kosakonia pseudosacchari TaxID=1646340 RepID=UPI000BE4E72D +---------LQEERLGARIGIAVIDTASGETV-SYRGDERFPLNSTHKALLCGALLSKVD +KGELALNETTQFAQSELVTWSPVTSKFVAPAMSWQQLCSAAITESDNTAANLLAKKLGGP +AAVTRFFADSGDSVTRLDRAEPELNSAVPGDVRDTTTPLAVSHTLQKLALGSALTPASRA +QLVQWMKEDKVAGALLRSTLPKGWMIGDKTGAGGYGSRSIISIVWPKKGAPRIVSIYVTD +TKATMAQSNDAIARIGKAIFS-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodanobacter sp. Root561 TaxID=1736560 RepID=UPI0006FC50A2 +--AIAARLAALERKHGGRLGVAMLDTGSGHHA-GRRIDERFLMCSTFKLLAVAAVLARVD +QGSEQLDRRIIFGKDVLLAWAPETSRHVGAPMTVGELCQAAITVSDNTAANLLLASLGGP +AAVTAFVRTLGDPLTRLDRTEPELNVGGPGELRDTTTPQAMLGDLRALLLGDALSAASRA +RLTGWLRACTTGLHKLRGGLPSGWQAGDKTGSGTQGESNDVAILWPPQRAPVLVTAYYAP +TSPDADVGARVLAEVGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Methylovirgula sp. 4M-Z18 TaxID=2293567 RepID=A0A371WPA7_9RHIZ +--AANARLVALEQEHGGRLGVAIGESGGNLTI-AHRADELFPMCSTFKFLAAAAILKRVD +AGAEHLDRAIAYGQADLLSYAPIAKRHVAEGMALGDLCAAAIQWSDNTAANLMLRELGGP +SAITRFARDVADRVTRLDRTEPTLNTAIPGDVRDTTSPAAMQRDLDAILLDDRLSAASRA +QLETWMIGNQVAGKRLRAGLPPSWRIGDKTGTGDNGTANTIAMIRPPSGTPILATVYYTG +SSESPDVLNSVHAEIGRIIAQVf +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis synnemataformans TaxID=61305 RepID=UPI000349E597 +-----REFEQLEEEFDARLGVYAVDTGTGEEV-AHRPDERFAYASTHKALTAALVLQQNT +--PEEMEEVVTFTEEDLVDYSPITEQHVDTGMTLTEVADAAVRHSDNTAANLLFEELGGP +DSFEDELEEIGDDVTDAERIETELNDWTPGDTSDTSTPRAMTESLREFTIGDALPEDRRE +VLNDMLVNNTTGDELIRAGVPEDWRVGDKTGAGSHGTRNDIAVLWPPEGDPIVLAVMSSR +EAEDAEYDNALIARAAEIVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000486158F +--DLNHEFRQLEESFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAVADAAVRYSDNTAGNLLLKHLGGP +ERFEQELKGIGDNVTDAARYETELNEAIPGDPRDTSTARALTEDLREYAVDDALEPTDRD +LLNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEPDASFDNALIAQATEVVIA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Burkholderia sp. NFACC38-1 TaxID=1566268 RepID=A0A1I0LUH6_9BURK +----EMRLAQIEAQVGGRLGVAILDTASGKQV-GWRMYERFPMCSTFKILLASLVLMRTD +HGQEDLTRKIVFSKREVVPSSPISGPRADSDMTIAELCEAALTHSDNTAGNLLLTSVGGP +TGLTAFARSIGDKFTRLDRNEPALNEAAEGDPRDSTTPAAILSDMHALLLGSTLSSSSRD +QLIAWLVSNKTGDARLRARLPKDWRIGDKTGTGDHGTVNDIAVVWPAGRAPVFVGAYLTG +ATATSTQRDEAIAKIGELVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. ST3 TaxID=2219062 RepID=UPI000DA654E6 +--AWNDALASIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD +QGKERLEARVHYPATDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDEVTRLDRTEPTLNEAAVGDPRDTTTPLAMLQTMQKLVLGNALSPTSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPQGGAPVLVTCYLTR +SMASPEQRDAAIARVARAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. BK441 TaxID=2512175 RepID=A0A4Q7RFW7_9GAMM +--PLEAALARIEQQAGGRLGVALHDAQGRRLA-GRREDERFPMCSTFKFLLAAAILHEVD +GGRLTLDRRVPIAASDLLGNSPVTEQHVGPRLSVAELCHATVTLSDNAAANLLLPQVGGP +PGLTAFLRASGDAVTRLDRTEPTMNLFAPGDDRDTTTPAAMAGNLRRLLLGDVLKPVSRA +LLVAWLRDNRTGGKRLRAGLPAGWRVGDKTGFNGEDTTNDIAILWPPGAAPLLLATYLQG +AKVDPDGQNAALAAVAAAVAR-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces viridifaciens TaxID=48665 RepID=A0A1L9DG14_STRVF +------AFKDLEQHFGARLGVYAVDTGSGREV-AYRSDERFAFASTIKSLLTGALLRTAS +--DQELDKVVTYRQDEVLTWAPITSRHVDTGMKVRDLAAAALEYSDNTAANLLMTELGGP +ENLQRTLRELGDPTTNVNRNEPTLNEATPGDPRDTSTPRAFAADLRRYVLGDVLTEDRRR +MLTDWMVGNTTGAPFIRAGVPAHWKIGDKTGNGGYGTRNDVAVAWPSGGSPVVLVVMSDR +GKADATSDDALIAEATKAVVT-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces atratus TaxID=1893 RepID=A0A1K2D8S7_STRAR +----TGRFKELERKFDARLGVYAIDTGTGREV-THNDGERFAYASTFKALAAGAVLRKYS +--VDGLDEVITYSRDDLVSNSPVSEKHVGTGMSLGALCDAAVRFSDNTAANLLLDRLGGP +RGLDAVLAGIGDDVTRMEHGEPQLNQWSPGALSDTSTPRALAGDLRAFVLGGVLEKGERA +QLTKWLRTNATGDELIRAGMPKNWVIGDKTGSGGYGTRNDIAVVWPPDKAPIVVAILSNR +SEPDADYDNELIAQAASVVAD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID11233 TaxID=2706029 RepID=A0A6B3ET84_9ACTN +--RTEQAFRDLERKFDARLGVHTLDTGSGRTV-THRPDERFAYASTCKALLVGAVLHKNS +--LRQMDRLVRYGRDDLVSASPVTERHVATGMTLRELSDAAIRYSDNTAANLLFHELGSP +RALQEALRALGDDVTRCDRYETALSDATPGDPRDTSTPRALATGLRAYVLGNTLPSDKRA +VLTDLLRRNTTGDNTIRAGVPDHWQVGDKTGTGGYGTRNDIAVIWPPGAAPITLAVLTRR +DAKDAERDDALIAGAAKVALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia spinosispora TaxID=103441 RepID=UPI000420E0F8 +--RATAELADLEARFVGRLGVYALDTGNGATV-GHRADELFPMCSTFKVLAASAILRLRT +QQPGLLDRVVHYTQAQMVDGSPISSTHLADGMTVAAMCAAAIQYSDNSAANQLLDILGGP +RGVTAFVRTLGDPLTRLDRYETDLNIVPPGEVRDTSTPEWMGKNLRALALGDALDPAGRD +QLVEWMVGNTTGATRIRAGLPNGWRVGDKTGGGARNEINDIAVCWPPNRAPLVIAVYTAP +TDPNAKGDGKVLADAASIVVR-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2Z4C2F4_KLEPN +--ETLVKVKDAEDQFGCTSGLHRTWISTARSFeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces abyssalis TaxID=933944 RepID=A0A1E7JPW6_9ACTN +----DREFEELEREFGARLGVYAVDTGSGREV-AYNDGRRFAYNSTFKALAAGEVLRRHS +--PDGMDRRITYSRDDLIANSPVTAKHVGSGMTLDELCDAAVRYSDNTAANLLFDVLGGP +EGLDAALEDIGDDVTRMERREPQLSRWTPGSTRDTSTPRALAGDLRAFVLGDVLGEAERK +QLSEWLRTNTTGDELIRAGVPQDWVVGDKTGSGSYGGRNDIAVLRPPGGAPIVVAILSHR +KERDAEFDNELIAKAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium yuanmingense TaxID=108015 RepID=UPI0012F81208 +-----SEFESYERESGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAANVLARVD +RGEEQLAAMIPYGQADLLEYAPVARENLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSQPGDPRDTTTPAAMVGNLRRLVTGEALSPASRT +LLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYTQG +GTPSATRITSAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Shinella sp. DD12 TaxID=1410620 RepID=A0A021XGS7_9RHIZ +-eDLAQRLAALEARHGGRIGVAIHNLSTGARL-GHNTDERFLMCSTFKALLAGHILARVD +RGEETLDRRIVVKKADLVDWSPVVETRVGGKISIAELCEATITFSDNAAANLLLAASGGP +EAVTAFLRGLGDAVTRLDRTEPTLNYETPDDVRDTTTPTAMVETLRRLVFADVLSARSKA +QLAAWLVMNKTGDARLRAGFPADWMTGDKTGTNGAGNANDVAIAWSPDRGAIIVAAFCEI +PGISGDERNAVIAEIGRIAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003FFE7EE +--DLSHEFRRLEERFDARLGIYAVDTGTGRTV-RYQADERFAYGSTFKALAAAAVLDATT +--DAELEQVVRYSADDLVDYSPITQQHVAEGMTLRAIADAAVRYSDNTAGNLLLRHLGGP +ERFEQELKGIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPADRD +VLNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEPDASFDNALIAEATEVLL--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia testacea TaxID=248551 RepID=UPI0002D4592C +---ATTRFADLEAAHGARLGVFAVDTADGRSV-AYRDGERFPMASTFKGLACGALLHEHP +LSSGFFDRVIRYPRTDLVENSPVTEQHVDTGMTVSALCEAAITVSDNTAGNQILKLLDGP +AGFTAFLRTLGDDTSRLDRWETELNTAIPGDERDTTTPAALAADYRALVVGDSLAEPERA +QLSAWLVASATGGNRIRAGLPPGWKVGNKTGSPAYGSALDVAVAWPPGRAPLVIAVLTTK +SEQDAEPANDLVAAATRAAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhizobium sp. BK315 TaxID=2512135 RepID=A0A4R3G8D3_9RHIZ +----EAQLAALESKYPGRICVSILDVASGRRI-EHRAGERILMCSTFKALAAALVLARVD +KGEEKLDRRIHYKKSDLIDYSPATEPNAGENMTVGELCAAAVTLSDNTAANLLLASFGGP +GAITTFCRSIGDEITRLDRTEPTLNHATPNDERDTTTASAMLENLQRLLFTNVLTPASRS +QLAAWLITNKTGDTRLRAGLPKDWLVGDKTGTNGHGNANDIAVLWPTKRAPIIVTAYCEI +PAIAADERNAIIAEIGRIAT--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A2E2ZV53_SPHSX +-------FDDLARKLDGGIGISALDTGSGRRV-DFDAISRYSLCSTFKLPLAGMILALND +AGQLALNETIAFTAADRVPYAPFIERHMDRGAAIAELCEAAVTVSDNVAANLLLRRIGGP +EAFTQWLRSIGDTTTRLDRIEPDLNSNIPGDPRDTTTPAAMLDTVHKLALGNVLTPASRA +QLAAWMVACETGDKRLRAGVPSEWRVGDKTGTSTNGASNDVAIIWPPESAPILIACFINN +DRVTAEDRDAAHAEVARRILHAf +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia kruczakiae TaxID=261477 RepID=UPI0007A3DA4A +------GFRDLEARLHGRLGVYALDTGTGRAV-EYRPDERFPYCSTFKALAAGALLSTLP +--PAELDRRVTYTRADLVPNSPVTEQHVDQGMTLREIMDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAGDLRHYVLDPSVAADDRD +VLTGLLRANTTGAALVRAGVPVGWQVGDKTGAGDYGTRNDIAVAWPPGRAPIVLTILSTR +DRPDAEYDNAAIARAATIAI--- +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter sp. R4-368 TaxID=1166130 RepID=R9VHD3_9ENTR +------AVARLEEHLGARIGIAVVDTASGEAV-SYRGDERFPLNSTHKALLCGALLSKVD +KGELALNETTQFAQSELVTWSPVTSKFVAPAMSWQQLCSAAITESDNTAANLLAKKLGGP +AAVTRFFADSGDSVTRLDRAEPELNSAVPGDLRDTTTPLAVSHTLQKLALGEVLTPRSRA +QLVQWMKEDKVADALLRSTLPKGWVIGDKTGAGDYGSRSIISIVWPKKGAPRIVSIYITD +TKATMAQSNDAIARIGKAIFS-- +>[subseq from] Beta-lactamase n=1 Tax=Shinella sp. JR1-6 TaxID=2527671 RepID=A0A4Q8MM99_9RHIZ +-eDLAQRLAALEARHGGRIGVAIHNLSTGARL-GHNTDERFLMCSTFKALLAGHILARVD +RGEETLDRRIVVKKADLVDWSPVVETRVGGKISIAELCEATITFSDNAAANLLLAASGGP +EAVTAFLRGLGDAVTRLDRTEPTLNYETPDDVRDTTTPTAMVETLRRLVFADVLSARSKA +QLAAWLVMNKTGDARLRAGFPADWMAGDKTGTNGAGNANDVAIAWSPDRGAIIVAAFCEI +PGISGDERNAVIAEIGRIAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces vinaceus TaxID=1960 RepID=UPI0005BB7E11 +----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSAFKALQAGVVLGKYS +--LDGLDQRVTYTRKDLVANSPVTEKHVGTGMTLKELCDASVRYSDNTAANLLFDHVGGP +RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLGEALPAPERE +QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR +ATKDAEPSDELIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces mexicanus TaxID=178566 RepID=UPI001357C54B +--DTEDRLSDLERRYGARLGIWARNTRTGHVV-AHRAGERFAMCSTFKAFAAAAILRDQD +-RCAPLDRLIAYPPADLLPNSPRTEEHTGTGMTVGELRAAAIQYGDTTAGNLLLRQIGGP +AGLTRFFRSLGDPVSRLDRWEPDLNTAIPGDPRDTTTPQALGRTLERLTLGDALTGADRT +RLVDWMKGTTTSAERFRAGLPQGWVVADKTGTGDYASAHDVGVAWTTRNTPLVLTVLSSR +ATADAPVDNALIADAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces puniciscabiei TaxID=164348 RepID=A0A542SYW1_9ACTN +-----AELTELERRHGARLGVYARNARTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDHG +-GCAPLDKVIHYPPYDILPNSPRTAEHVDTGMTVAELCAAAIQYSDNAAGNLLLRQIGGP +TGLTGFFRSLGDRVSRLDRWETDLGSAIPGDPRDTTTPRSLGRSFERLTLGRALADADRE +QLVTWLKGNTTSAARFRAGLPGDWVLADKTGTGDYGSGNDIGVAWTTRGTPVLLTVLSAK +PAQDAPADDALVAEAARIVA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=UPI00056E533C +--STARNFAALEAASGGRLGVTLLDTGNGQRI-GHRQDERFPMCSTFKFALCATVLRLAD +QGKLSLDRRLAMTTQDLLSHAPLTARHVGKDVTVRDLCRATMVTSDNPAANLLLRVVGGP +AGVTAFLRASGDDVTRNDRYEPDVNLFAPGDPRDTTSPAAMAASLQRLVLGERLQPASRQ +QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ARLDDAGRNDVLRQVAVIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0003A2E760 +----DREFRRLEKRFDARLGIYAIDTGTGRTV-CYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKEIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWIVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASSDNALIAQATEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium symbiodeficiens TaxID=1404367 RepID=UPI00140FE49E +------ELETYERESGGRIGVYAENLTTGKKL-TWRADERFVMCSTFKASLAACVLARVD +RGGEKLAATIAYGKADLLEYAPVAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVLGEALTPASRA +LLTEWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVAWPKPETPILMAAYTQG +GTPNAAQIEAAFARIGRMVAE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Verrucomicrobiaceae bacterium TaxID=2026800 RepID=A0A4Q3AQT0_9BACT +--------AKLESRHGGRLGVTTLDLGERTSF-SHRGGERFAMCSTFKFLLSAAVAARVD +AGDEQWDRKVAYGKKDLIPWTPVTGKNLKAGMTVADLCEASMTWSDNTAANLLLSSVGGP +DGLTRYLRSIGDETSRLDRTEPDLNSNVRGDERDTSTPEAMIATMEKLLFGKSLTEASKE +KLIGWLVANHTGDKRIRAAMDPAWKIGDKTGTGENGAANDIAVVWPEDRKPCLIVVFYDA +AQATAEQRDTVIADAAKLV---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A482LQ94_ACIBA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLPSRQ +QLIDWMEADKFAGPLLRSALPAGWFIADKSGAGERGSPGIIASLLPDGRPSRSVVIYSTG +SQ--------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Stappia sp. TaxID=1870903 RepID=A0A2E6Y902_9RHOB +--EVADTVSRLEQRLGGRIGVVLRETGADTPVvAIRADERFPTASTFKPSLCAAVLARVE +RGEERLDRKIAYQPSDLVTYSPVTEKYAGGPLTIDALCEASVSVSDNTATNLLLTTVGGP +KGVTTFLRGIGDDTTRLDRTEPELNASIPGDPRDTTTPAAMARTLETLILGAGLAPASRK +RLETWMVNDKVADALIRKHLPPTWRIADKTGAGANGTRGIISVIWPETGTPHLAVIYMTG +SSADITTRNAAIAEIGKAMIS-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces gilvosporeus TaxID=553510 RepID=A0A1V0TKQ5_9ACTN +---TEATLRDLERQYGARLGVFARNVRNGRVV-AHRAGERFAMCSTFKTFAAAAVLREHG +-RCAPLDKVIHYPARDILPNSPITEQHVDTGMTVGALCAAAIRYSDNAAGNLLLRQTGGP +GGLTDFFRSIGDPVSRLDRWETDLNAAVPGDPRDTTTPQAIGRSLERVTLGRALDEAGRR +HLVTWLKGNTTSGERFRAGLPGDWIVADKTGTGDYASANDIGVAWTTEKTPIVLVVLSSK +PARDATVDNALIADAARVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Actinoallomurus bryophytorum TaxID=1490222 RepID=A0A543CMX2_9ACTN +-------FKDLEDEYGVRLGVWALDTGTGRTV-TWRAGERFAYASTYKALAAGELLRRDP +---GGLDDVVTYTKADLVTYSPITEQHVGTGMTVRALCDAAIRYSDNTAGNLLLRRLGGP +KGLQAALRRLGDHTIHADRYETALNDAVPGDVRDTSTPRALGTDLRKYAIGNVLPKSGRG +LLDDWLRRNTTGTAMIRAGVPAGWTVGDKSGAAEYGTRNDVAVAWPPHRAPIVLAILSTK +TTQDATYDDALIAAAARVTV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Kushneria indalinina DSM 14324 TaxID=1122140 RepID=A0A3D9E047_9GAMM +-qEVARRLQALEQQHKGRLGVALMNVGTGAVV-SHRGDERFLFNSTGKVFIAAAALAQVD +RGEESLDRRIEIKSSDLTGWTPVTEKQMGSPMTIAELGQAAVAWSDNAAANLLIESLGGP +AEVTAFLRGIGDTTTRLDRTEPTLNEHHDGDERDTTTPRAMMQTLRTLLLGEVLSPASRH +QLAAWMIEGKTGDARLRAGMPSGWLVGEKTGTNSVGNAGDIGIAWPSDRGAVIVIAYVYL +PEADKAQRDQVIAEIGKLAAK-- +>[subseq from] Beta-lactamase n=2 Tax=Roseovarius sp. 217 TaxID=314264 RepID=A3VZZ2_9RHOB +--RLTQTITQIEQTLDARVGLHIHDSATGWTV-THRPNERFLMASTFKAMLCGAVLSRVD +KGTLALDEPLEITEQDILEYAPITESEIGKTMSLGELCFAALDLSDNTAANLLIDRLGGP +HEVTAFLRAIGDPVSRLDRREPDLNTFTPGDPRDTTTPAAMASTLETLLAGDALSPQSRA +QLVKWMSAGGVTGALIRASTPKGWQVADKSGSGAY-NRNIVAMVTPPDQSPYVITMFLSD +ADADFATRNAAVITLSKAVMD-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00039AE6B4 +--DLNHEFRQLEESFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAVADAAVRYSDNTAGNLLLKHLGGP +ERLEQELKGIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD +LLNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEPDASFDNALIAQATEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodanobacter sp. TND4EH1 TaxID=1907399 RepID=UPI000C170DD6 +---AAGRLAALERKYGGRLGVSMLDTGSGQQA-GHRADERFLMCSTFKLLAVATVLGRVD +KGREQLDRRITYGKEVLLAWAPVTSRHVGADMTVGELCEAAITMSDNTAANLLLASLGGP +GVVTAFVRTLGDPLTRLDRIEPELNVGGPGDLRDTTTPAAMLGDMRALLLGDALAAVSRQ +RLIGWLRACSTGLDKLRVGLPAGWDAGDKTGSGAQGESNDVAILWPPRRAPMLVTAYYAP +ATPDKATSVRVLAEVGRITA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. Root179 TaxID=1736482 RepID=A0A0Q8LF36_9GAMM +--AIAARLAALERKHGGRLGVAMLDTGSGHHA-GRRIDERFLMCSTFKLLAVAAVLARVD +QGSEQLDRRIIFGKDVLLAWAPETSRHVGAPMTVGELCQAAITVSDNTAANLLLASLGGP +AAVTAFVRTLGDPLTRLDRTEPELNVGGPGELRDTTTPQAMLGDLRALLLGDALSAASRA +RLTGWLRACTTGLHKLRGGLPSGWQAGDKTGSGAQGESNDVAILWPPQRAPVLVTAYYAP +TSPDADVGARVLAEVGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus mangrovi TaxID=1491830 RepID=UPI0012BA92BF +------GFEELEKEYQAKLGVYALNTGSSKSV-SYNADERFAYASAHKALAVGTLLKQKS +--IGELEEKIHFTEDDLVNYNPVTEKYVNEGMTLKELSDASIRYSDNTAANLIFDAIGGP +EGFKEALREIGDDVTNPERIEPDLNDVNPGETRDTSTPKALAESLQAFTLGDVLSGEKQE +LLNDWLKRNTTGDNLIRAGVPEDWVVGDKTGSGSYGTRNDIAVIWPPDDDPIILAILSSR +ENADADYDDELIAKAAKIAVEQ- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. GP55 TaxID=1798190 RepID=A0A2N3UEE5_9ACTN +----TEAFAQLEQQFGARAGLYALDTGSGREV-AYHADDRFAFASTIKSLSVGTLLRHAS +--DAELDKVVTYHQEDVLSWAPVTSKHVADGMKLRDLATAAIEQSDNTAANLVTAELGGP +AAVQQALRDLGDRTTNVNRTEPTLNEATPGDTRDTSTPRAMATDLRQYVLGDTLAGDHRQ +LLTDWLVGNTTGGPYIRAGVPTGWKVGDKTGNGGYGTRNDIGILWPNDGAPIVIAVLTDR +GKPDAKSDDALIAQATKAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNZ279 TaxID=2035251 RepID=UPI000C1991C2 +----RARFTALERKYGARLGVYALDTGSGATV-SYRADERFAFCSTFKAFAAAAVVHRNP +--RSHLDKRVTYTEADVDSISPVTEDHVATGMTIRQLCDAAVRYSDGTAGNLLMRDIGGP +EQLTAYLRGLGDKVSRMDNYEPELNQVRPGDPRDTTTPEAVAADYRKLVLGDALSGDERA +LLKGWLLRNTTGKKRIRAGVPRGWKVADKTGTGNWGRANDIAVVWPPHKAPLVMAVLSDR +PGYRARPKNSLIAKATEQIV--- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. 35-64-16 TaxID=1970312 RepID=A0A258NAG4_9BURK +--QWSDALAGIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD +QGKERLDARVHYPVADVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANLLLARHGGP +AGFTAFVRSLGDGATRLDRTEPTLNEAAGGDPRDTTTPLAMLQTMRKLVLGGALTPASRA +WLQRWMVETTTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVLWPPSGAPVLVTCYLTR +STAQPEQRDAAIAQVARAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas sp. GT TaxID=1971364 RepID=UPI0009F480E6 +--NLLTEVDRIERQLDARVGFAAYNLETGQRW-EYNADQLFAMSSTFKTLACASLLQRVD +EGNEQLERRVKVSASDIVTYSPVTEAYADNRISLFELCEATMTTSDNTAANLILQAIGGP +QAVTEFVRELGDSVTRLDRWETELNEATPHDERDTSTPNAMVSNLEKLVVGNALSPQSKN +QLREWLVNNEVADGLFRSHMPDEWVIGDRTGAGGFGSRSITAVIWPPEREPTIVAFYITE +TDASFEERNSAIAELGSVIIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis nigrescens TaxID=381445 RepID=UPI000683D936 +--EHHDQLVELERKFGARLGVYALATGTGAAL-AYRADERFAFCSTFKGLAAAAVLRRNP +--PSHLDTVVTYTEDDLLKSAVITRQHVATGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP +AELTTYVRGLGDAVTRMDRIEPAITEATPGDPRDTSSPRALGSTYREIVLADALPAEQRA +FLRDLLERNTTGAQRIRAGVPREWTVADKTGTGDYGTANDIAVVWPPNAAPLVIAIMSSK +AAKDAEYDQTLIAEAAAYVVT-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces klenkii TaxID=1420899 RepID=A0A3B0AZZ2_9ACTN +---AERAFGELEKRYDARLGVYAVDTGSGRSV-ANRPDERFAYASVCKAFLAAAVLKRNS +--LKQLDRLVRYSHDVPVGHSPVTTRHVDSGMTLRELCDAAVRYSDNGAANLLFDELGGP +KGLQDALAATGDRVTRADRYETDLSEGTPGDPRDTSTPRAMAAGLRAFVLGDALAPDKRS +ILTDWLKRNTTGDTLIRAGVPGGWQVADKTGSGGYGARNDVAVLWPPKAAPIVIAVFSSR +GAQDAKRDDTLIARAAEAAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000418A2CC +--DLHHEFRQLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT +--DAELGQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLRHLGGP +ELFEQELKEIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEPDASYDNALIAEATEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000534D68D +--DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDATT +--DAELDQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEQELKGIGDNVTDAARYETELNEATPGDRRDTSTARALTEDLQEYAVDDALDPTDRD +ILNAWLRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEPDASFDNALIAEAAEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB519C +----EAQLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD +KGDEKLDRRIHYKKSDLIDYSPATKPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP +EAITTFCRSIGDEITRLDRTEPTLNYDTPTDERDTTTASAMLENLRRFLFTDILTAASRS +QLAAWLIANKTGDTRLRAGLPKDWLVGDKTGTNGYGNANDIAVLWPSKRAPIIVTAYCEI +PAIAADERNAIIAEIGRIAA--- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Bacteria (miscellaneous) TaxID=49928 RepID=V5SM17_9BACT +-----DDFAALEAASGGRLGVTLLDTATGQRI-GHRQDERFPMCSTFKFVLSAAVLHLAD +QGTLSLDRRVLVRQQDMLSHAPVTMRHIGKDLTVRDLCRATMVTSDNPAANLLLGVVGGP +AGVTAFLRANGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRFVLGEVLKPASRQ +QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGKDTTNDIAILWPLGGAPWVLTSYLQG +ATVDDAGRNDVLRQVAVI----- +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. HSS6-12 TaxID=2720024 RepID=UPI00143AF055 +--TWREQLRELEQGYAGRIGMYARHMGTGRTL-CYRADERFPLLSTFKVLVSAAVLDRAR +SAPGLVDRRIRWTEADLVDYSPVTEAHVADGLTVAQLCHAAITRSDNTAGNLLLRQVGGP +VGLTGYLRRLGDGVSRLDRWETDLNVWAPGERRDTTTPAAMGRDLAALTVGRALHPDDRT +TLVDWMRATVTGDRRIRAGLPAGWTVGDKTGSSNYGAANDVAVAHPPTGAPLVLAIYTRR +ETQGQPYDEAIIAETARVLA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=G8ENQ3_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPIMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYT-- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. TD01 TaxID=999141 RepID=F7SP12_9GAMM +--NLLTEVDRIERQLDARVGFAAYNLETGQRW-EYNADQLFAMSSTFKTLACASLLQRVD +EGNEQLERRVKVSASDIVTYSPVTEAYADNRISLFELCEATMTTSDNTAANLILQAIGGP +QAVTEFVRELGDSVTRLDRWETELNEATPHDERDTSTPNAMVSNLEKLVVGNALSPQSKN +QLREWLVNNEVADGLFRSHMPDEWVIGDRTGAGGFGSRSITAVIWPPEREPTIVAFYITE +TDASFEERNSAIAELGSVIIE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB02_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPEMNRFAEGDPRDTTTPAAMAGSLQRVVLGQVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLRA +GQISYEQQAAVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. H13 TaxID=2605988 RepID=UPI001239647F +-----REFEQLEEEFDARLGVYAVDTGTGEEV-AHRPDERFAYASTHKALTAALVLQQNT +--PEEMEEVVTFTEDDLVDYSPITEQHVDTGMTLTEVADAAVRHSDNTAANLLFEELGGP +DAFEDELEEIGDDVTDPERLETELNDWTPGDTSDTSTPRAMAESLREFTLGDALPEDRRE +VLNDMLVNNTTGDELIRAGVPEDWRVGDKTGAASHGTRNDIAVIWPAEGDPIVLAVMSSR +EAEDAEYDNALIARAAEVVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MZ04 TaxID=2559236 RepID=A0A4R9EKR3_9ACTN +--KAASRFAALEREHDARLGVYALATSTGAVL-THRADDRFAFCSTFKTLAAAAVLDRKP +--LRHLEKVVTFSEADVDSISPVTENHVATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGT +RRLTAYLRGLGDAESRMDQFEPELNDNRPGDPRDTTTPRAIARDYQELVIGKALPARKRA +LLKDWLERTTTGEKRIRAGLPKGWTLAHKTGTGNYGRANDIAVVWPPTAAPIVLAIMSDR +SGYDAEPREALIADAAAYVA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CNZ279 TaxID=2035251 RepID=A0A2G7EJA0_9ACTN +----RARFTALERKYGARLGVYALDTGSGATV-SYRADERFAFCSTFKAFAAAAVVHRNP +--RSHLDKRVTYTEADVDSISPVTEDHVATGMTIRQLCDAAVRYSDGTAGNLLMRDIGGP +EQLTAYLRGLGDKVSRMDNYEPELNQVRPGDPRDTTTPEAVAADYRKLVLGDALSGDERA +LLKGWLLRNTTGKKRIRAGVPRGWKVADKTGTGNWGRANDIAVVWPPHKAPLVMAVLSDR +PGYRARPKNSLIAKATEQIV--- +>[subseq from] Beta-lactamase 1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=BLAC_BACCE +-qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS +--IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGIPTDWVVGDKSGAGSYGTRNDIAVVWPPNSAPIIVLISSKD +EK-EAIYNDQLIAEATKVIVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. Tu 6176 TaxID=1470557 RepID=A0A022MN91_9ACTN +--RATDALRALEERYSARLGVHARNTRTGQSV-GYRAGERFALCSTFKVFAAGAVLRDHA +-GSAPLDKVVRYPDRDILLNSPVTQQHVGSGMTVGELCAAAIRHSDNCAGNLLLRELGGP +AGLTAFFRSLGDRVSRLDRWEPDLNSAGPGELRDSTTPEALGASLERLTVGDELSGAARE +QLLTWLKGNTTSDRRFRAGLPRGWVVGDKTGTGDYASANDIGVAWTTRGTPLVLVVLTSK +DAPDATVDEALIADAAAVLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas panacihumi TaxID=676599 RepID=A0A0R0A474_9GAMM +---LDAAWAEIEQRAGGRLGVALRD-AEGRYLaGRREDERFPMCSTFKFLLAGAILHEVD +AGRLRLDRRVPIAATDLLGNSPITERHVGPKLSVGELCQATIIRSDNAAANLLFPLVGGP +EGLTAFLRASGDAVTRIDRNEPTMNLFAPGDDRDTTSPAAMAGNLRRLLLGDVLKPASRG +QLTAWLRDNRTGDKRLRAGLPAGWQVGDKTGFNGEDTTNDIAILWPPGGAPLLLATYLQG +AQVDPDGQNAALASVARAVS--- +>[subseq from] Class A beta-lactamase n=1 Tax=Telmatospirillum sp. TaxID=2079197 RepID=A0A6A8QL72_9PROT +--DFERRLKTLETASGGRLGVAFVDKETGAVR-GHRLNERFLMCSTFKLLLVGAVLSQVD +SGKERLDRRIMIRSEDILEYAPVTRTHLDGPMTVSELCDAAMTLSDNTAANLLLDALGGA +ETLIAFARSLGDPVTRLDRKEPDLNLMVADDIRDTTTPAAMAADLDALILGDRLSPEMRH +RLTKWLIGNQTGAHRLRAGLPHGWKIGDKTGSGV-GIANDVALVWPPGRAPFLLSVYLTG +ATGTAVQRDAVLAETARLAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. NEAU-S7GS2 TaxID=2202000 RepID=A0A2U8VL18_9ACTN +--RAAKDLAQVERRYHSRLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAAVLLKRGT +--DDELNSVINYRASDLEDYAPITKRHVGEGMTLRDLIKAAVQYSDNTAANLLLDRLGGP +AGLQKALRGMGDRTTRTDRTEPALNEAKPGDPRDTSTPRALGTDLRRFVLGDVLPEGRRQ +LLTHVLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPAGGSPIVVAVLSDR +GSKDAASDDALIKDATKT----- +>[subseq from] Beta-lactamase n=1 Tax=Mycetocola zhadangensis TaxID=1164595 RepID=A0A3L7J112_9MICO +--AADAQFGELEAKFDARLGVYALDTGTGLAL-EYRSDERFAYASTIKVFASAVLLDQTT +--DSELDSLVRYDESDLLDYAPITEQHVDTGMTLRELGDAAVRYSDNTAANLIFERIGGP +TGLATALKAMGDDVTQVDRTEPELNETTPGDPRDTTTPEAFAVGLEALILGDALELADRE +TLTEWLVGNTTGDNLIRAGVPTEWTVGDKTGSAGYGTRNDIAVIWPTEGDPIVLAVLSSR +AEPDAEYDDDLIAEATAVAID-- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis jejuensis TaxID=330084 RepID=UPI000526C0E9 +----QPDFAALEKTFGARLGVYAIDTGTGREI-AYHADDRFAYASTHKVFTAAAILHRGD +----DLHRMITVRSSDLVPYSPITEKHLDTGMSLQSVLDAALRYSDNTAGNLMFREIGGP +EGLTADLHRSGDTVTHVDRIEPALNDTAPGDIRDTTTPRAWAADLRAAVLGSALGPDRQA +VLTGMMRASTTGGNLIRAGVPDGWQVADKTGTADYATRNDIAVVWPPNRAPIVLAVLSDR +PQKDAKADDKLIAQATAAVVK-- +>[subseq from] Beta-lactamase n=2 Tax=Acidovorax sp. 62 TaxID=2035203 RepID=A0A2G6Y669_9BURK +-qQWQQALAQIERNAQGRLGAALLDTGSGLAL-GWRQDERFAMCSTFKLPLAGWMLALVD +QGKERLDARVQYPASEVVDYSPVSGSKAGAGLTVGELCSATVSLSDNTAANLLLARHGGP +SALTAYLRTLGDTATRLDRNEPTLNEAAVGDPRDTTTPLAMLQTMQKLVLGDALTPASRA +TLQRWLVETSTGDKRLRAGAP-GWRVGDKTGTAGSGTTNDIGVLWPQGGAPVLLTCYLTQ +SKAKPEQREAAIAEVARSAL--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia bhagyanarayanae TaxID=1215925 RepID=A0A543EXQ2_9NOCA +------HLIDLERKFDARLGVYALATGTGAVI-AHRADERFAFCSTFKGLVAAAVLQRNP +--LSHLDTVVSYTEADLLKNAAVTPKHLDTGMTIRDLCDAAVRFSDGTAGNLLLRDLGGP +AELTAYARGLGDTVTRMDRTEPTITQAIPGDPRDTTSPRALGTDYQQIVLGDALPADKRA +FLRDLLERNTTGAQRIRAGVPQGWTVADKTGTGDYGTLNDIGIVWPPDSAPLVIALMSSK +ATADARYDQALLAEAAAYVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0005A06F5E +--ELVARLRELEARHDARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTLAVAAVLRDLD +HDGTFLARRIRYTAADVKRWSPRTEENLARGMTVAELCDATLRFSDNTAANLLLRELGGP +TAVTRFVRSTGDRTTRLDRWEPELNSAEPWRESDTSTPRAIGRTYGRLLLGDALPHRDRE +RLTRWMLANTTSGERFRKGLPADWLLADKTGGGRYGTNNDAGVTWPPGGGPIVLAVMTTR +SLEDAPVVDPLVAEAAALVAA-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=UPI00119F647D +----ADDFAALEKASGGRLGVTLLNTATGARV-GHRQDERFPMCSTFKFVLAATVLHLAD +QGTLALDRRLPVRQQDMLSHAPVTKRHVGKDLTVRDLCRATMVTSDNPAANLLLGVVGGP +AGVTAFLRAHGDAVTRNDRLEPDMNRFAPGDPRDTTSPAAMAASLQRLVLGEVLKPASRL +QLADWLIDNETGDTRLRAGLSPAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ATVDDAGRNDVLRQVAVI----- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=UPI00138F784F +---AAADFAALEAAAQGRLGVAVLDAAGGRYLgGHRPDERFPMCSTFKAVLSAAVLAQAD +RGALELDLRLPVRRSDIVSHSPVTRRHVGKDLTVRDLCRATMTTSDNAAANLLLGRIGGT +AGLTAFLRGIGDEVTRSDRMEPEMNRFAPDDPRDTTSPRAMAASLARCVAGDVLAPASRL +QLADWLIDNRTGDDCLRAGIGDGWRVGDKTGSNGTDTRNDIAIVWPLQGRPWTVAAYLQG +ARVDSPARDAVLARAGALAAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_032 TaxID=2175659 RepID=A0A2W1U1W9_9MICO +--AAERAFAALETEHDARLGVVAIDTGSGVGV-AHRADERFAFASAAKVFIAAAVLDAAA +--PDDLDAVVPIGQGDVLSYAPVTGQHVGSGMTVRELLAAMVRSSDNTAANLLVARVGGP +AAVQRWLRGIGDDVTRVDRVEPALNEAVPGDERDTTTPEQFAADLRTVLLGGALDPDDRA +LLVDLMRGTTTGAGTIRAGVPEEWTVADKTGTGSYGVRNDVGIVTPPGRDPIVLVVMTGH +DTADAEPDDALVAAATRTAL--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. wa22 TaxID=1828244 RepID=A0A5Q4SIU1_9ACTN +-----RAFQELERRFGARLGVYAIDTGSGASV-THRPDERFAYASTCKALLAGAVLDGHT +--LQQLERRVRYGPGDLVANSPVTERHVDAGMTLRALCDAAVRHSDNAAANLLFDEIGGP +RGLQDALIALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGTEKRA +VLTDWLRRNTTGGALIRAGAPADWPVGDKTGTGGYGTRNDIAVLWPPESAPVTIAVLSRR +STRGAKPQDALVAEAARVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. N3-2A TaxID=2014541 RepID=A0A220RC61_9GAMM +--NLLTEVERIEEQLDARVGFAAYDLETGQRW-EYNADQLFAMSSTFKTLACASLLQRVD +EGSEQLERQVKVSASDIVTYSPVTEAYADNRISLFELCEATMTTSDNTAANLILQAIGGP +QAVTAFVRDLGDSVTRLDRWETELNEAAPHDERDTTTPNAMVSNLEKLVVGNALSPQSKN +QLREWLVNNEVADGLFRSQMPDEWVIGDRTGAGGFGSRSITAVIWPPEREPTIVAFYITE +TDASFEERNSAIAELGSVI---- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. MOS003 TaxID=2133946 RepID=A0A2T2Q666_9BRAD +------ELETYERESGGRIGVYAENLATGKKL-TWRADERFVMCSTFKASLAACVLARVD +HGEEKLAATIAYGKTDLLEYAPVAKQNLAAGMSVGDMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALTPASRA +LLTEWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVAWPKPETPILIAAYVQG +GTPNAAQIEAAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2B1MP75_BACTU +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKED----AKLIADATKIVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. OK885 TaxID=1882770 RepID=A0A2N3ZD18_9ACTN +--------RELEARHGARIGAFAYNLRTKATV-RHRAAERFPICSVFKTLAAAAVLRDLD +RHGETLARRIHYTVADLAGYSPKTGEHLAGGMTVGELCGAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PAQDAAADSPLVAATASVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. CCBAU 43298 TaxID=1128178 RepID=UPI0004B277E3 +---APAELEAYERDSGGRVGVHAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEHLAAMIPYGQADLLEYAPVARQNLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLRRLVLGEALSAQSRL +QLTDWMVNCKTGANRLRGGLPPSWKIGDKTGNNGKDASGDIAVVWPKPDVPILIAAYTQG +GSPNAAQIAALFAQIGRMVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Terribacillus saccharophilus TaxID=361277 RepID=UPI000BA53BB3 +-----ASFSSLEETYDARLGIFAIDTGSGRTV-AYRENERFGFASTHKALSVGVLLQQKS +--MEDLNKRIMFTGDDLVNYNPITEKHVDSGMTLKELSEASISYSDNTAANLIFEEIGGP +DGFEDGLRKIGDQVTNSERIEPDLNNTQPGDTRDTSTPKAMAESLREFALEDHLSADKRQ +LLIDWLKGNTTGDELIRAGVPKDWEVGDKTGAGSYGTRNDIAILWPPEEEPIVLAIMSDH +DEADANANDDLIAEAAETAV--- +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium 62-8 TaxID=1895708 RepID=A0A1M3A9C1_9PROT +------PFRAIEARTGGRLGVAVRDTASGRHF-AWRGDERFAMCSTFKFLAVAMVLERAA +AGATDLDRAIAYGRADLLDYAPVTAKHVKAGMSLRDLCAAAIEWSDNTAANLILKQIGGP +AGLTRWLRGHGDTVTRLDRTEPTLNTAIAGDPRDTTTPIAMLADMARILVSEK-SAAFAA +PLLIWMRECRTADSKLRAGLPRDWRAGNKTGSGRNGTANDIAILWPPGRAPLLVAAYLTG +AKADAAARDAALADAGRVVAARf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces diastatochromogenes TaxID=42236 RepID=A0A233S7T5_9ACTN +----HTELGDLEQRYGARLGVYAHNVRTGRTV-AYRAGERFAMCSTFKAFAAAAVLRDHG +-GCAPLDRVIHYPPRDILPNSPKTEEHLATGMSVGDLCAAAIQYSDNAAGNLLLRQIGGP +EGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPEAIGRSFERLTLGRALDGTGRE +QLVTWLKGNTTSAERFGRGLPQGWVLGDKTGTGDYATANDIGVAWTTRGTPVVLAVLSTK +AAKDAPVDNALVADTARLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID724 TaxID=2690324 RepID=UPI001360F16E +----GRAFEALEKEYAARLGVYAVDTGTGTTV-AHRDGERFAYASTFKALAAGAVLRRYG +--LGGLERVVTYRREDLVDHSPVTEKHLATGMSLGALCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAGLGDEVTRMVRRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALGGPERA +RLTQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +TAADADHDNTLIAKAASAAVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00035CBA64 +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRHSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Kitasatospora sp. MMS16-CNU292 TaxID=2567942 RepID=A0A540WG95_9ACTN +----TEAFAQLEQQFGARVGLYALDTGSDREV-AYHADDRFAFASTIKSLSVGTLLRHAS +--DAELDKVVTYHQEDVLSWAPVTSKHVADGMKLRDLATAAIEQSDNTAANLVTAELGGP +AAVQQALRDLGDRTTNVDRTEPTLNEATPGDTRDTSTPRAMATDLRQYVLGGTLAGDHRQ +LLTDWLVGNTTGGPYIRAGVPTGWKVGDKTGNGGYGTRNDIGILWPNDGAPIVIAVLTDR +GKPDAKSDDALIAQATKAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0004963790 +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRHSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=A0A2A2CS85_9VIBR +-dSLTKQIALIEQQSGGRLGVAVLDTQNHKQW-QYHGDDRFPMMSTFKTLMCANALYLAE +QKKLNLNATTKVKESDLVTWSPITEKLIGQEITVQKACEATMLMSDNTAANIVLHQIGGP +EQVSQFVRSLDDKVTRLDRFEPELNQAIPGDKRDTTSPSAMVELLNTLLLQDGLNQESQQ +QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPVILSIYLTQ +TQLDMAQRNRVINRVANLVFEQf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000753545D +---ALDSIRSLEMSRGGRLGVAVLDTGSGRRL-RYRADESFAMCSTHKFLSAVAVLSLVD +QGKLALDKPVKYGKADLLDYAPVAREHVGRGMTIDELCAAATVWSDNTAANLLIELLGGP +AGWTRFARSIGDNASRLDRTEPALNSAIPGDPRDTTTPDAMLANLQQTLLGTVLSDSSRG +RLQNWMLSGTITDTLLRAGVPLTWRVGDKSGAGRNGTRNDIGIIFPPHASPILAAIYYTE +STGSLASREEVIAEVGGIIAKTf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000753675A +---ALDSIRSLEMSRGGRLGVAVLDTGSGRRL-RYRADESFAMCSTHKFLSAVAVLSLVD +QGKLALDKPVKYGKADLLDYAPVAREHVGRGMTIDELCAAATVWSDNTAANLLIELLGGP +AGWTRFARSIGDNASRLDRTEPALNSAIPGDPRDTTTPDAMLANLQQTLLGTVLSDSSRG +RLQNWMLSGTITDTLLRAGVPLTWRVGDKSGAGRNGTRNDIGIIFPPHASPILAAIYYTE +STGSLASREEVIAEVGGIIAKTf +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis kentuckyensis TaxID=218823 RepID=UPI000A381CB8 +-----PDFAPLERSFDARLGVYALDTGSGREV-VHRADERFGYASAHKAFSAAAVLQRTS +--IEDLAKVLTYRRADLQENSPVTEKHVDTGISLRDAIDAALRYSDNTAANLLFQQLGGP +PGLAAALRAIGDTTTHVDRTEPALNDLAPGDIRDTSTPRAMAGTLRTFALGDALPPEKRT +MYTDMMRANKTGANVIRAGTPAGWAVADKTGTGEYATRNDIAVVWPPGRAPIVLAVMSSR +QAEHAEHDDRLIAQAAKLVFD-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis japonica TaxID=208439 RepID=A0A075V010_9PSEU +--QFHDRLMELENKFDARLGVYALDTGGGGTV-EHRADERFAFCSTFKGVATAAVLQRNP +--LSHLETRVSYSRDDLMKHAPVTERHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +AALTAFTRGLGDTVTRMDRVEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTAEKRD +FLRDLLQRTVTGAGRIRAGLPSGWTIAGKTGTGEYGTLNDIAVLWPPGKAPIVLAVMSSK +PAKDAPYDEALLAEAAKYVVE-- +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sp. Leaf33 TaxID=1736215 RepID=A0A0Q4KNC8_9SPHN +--ALATAIAAAERRSGGRLGVAVLDLATGARF-DHRGDERFAMCSTFKFPLSGAVLAAAD +AGRLRLNRAVPVPRAPLPGNSPVVSKHKGSAMTVEQLCAATMTFSDNAAANLLLPLIGGV +DGFNAFVARLGDRTTRLDRQEPELNTAIHGDDRDTTTPTAMLNTMRALLFGPALTPAARA +KLTGWLVANTTGGTRLRAGLPRGWRVGDKTGSGENGTYNDVAVIWPGTRRPILVTCYLTG +ATVPQRAAHRIHADVGRAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00036DDC91 +------GFRRLEKRFDARLGIYAIDTDTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A2W6U227_9GAMM +-----ADFAALEKASGGRLGVCLWNPASGARY-GHRIDERFPMCSTVKYPLAAAVLRRAD +AGQLSLDQRVPVRASDILDHSPFTERHVGKTMTVRDLCRATMIVSDNAAANLLLPLVGGP +AGLTAFLREHGDRVTVSARNEPELNRFAAGDPRDTTSPAAMAGNLQRFLLGDVLGEASRQ +QLADWLIDNQTGDARLRAGLPQDWRVGDKTGSNGSDTSNDIAVLWPLGGTPWLLSSYLQG +SALDDDGRNGILRQVGELA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces hainanensis TaxID=402648 RepID=A0A4R4TK34_9ACTN +--SLAREFEALEREFDARLGVYVLDTGTGQEV-AYQADERFTYASTFKALAAGAVLHEYG +--SEGIDEVVTYTEDDLVDYSPVTENFVETGMSLSELCAATLWYSDNTAGNLLFDALGGP +DGLEAVLEELGDDVTEMDRYETELNEATPGDIRDTSTPRAFATNLREFLLGDILDPDERE +LLRMWMVTNTTGETLVNAGVPDGWTVADKSGAGGYGGRNDIAVVWPDDGDPLVMAIMSAH +DEEDAEHDDALIAEATAVAVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum chlorophenolicum TaxID=211589 RepID=UPI00067BC1BB +---IAQKLAELEKQSGGRLGVMAIDNASSDRI-GYRETERFPFCSTFKLILVSAILNRSL +EDSTLLQRRVRYDAADLVAYSPVTEKAVGAGLSVSGLCAAALQYSDNTAGNLLIRELGGI +GAVNEYARNIGDESFRLDRMETEINSAVPGDDRDTTTPLAMAQSLQRLVLGEILPPLQRR +MLVDWMRGNTTGGTRIRSAMPSDWVIADKTGGGDYGTTNDVAVIWPGSESPVILAIYFTQ +TVQDAPPRNDVVATAARIIGEHf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) TaxID=953739 RepID=F2R4A0_STRVP +--ELVARLRELEARHDARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTLAVAAVLRDLD +HDGTFLARRIRYTAADVKRWSPRTEENLARGMTVAELCDATLRFSDNTAANLLLRELGGP +TAVTRFVRSTGDRTTRLDRWEPELNSAEPWRESDTSTPRAIGRTYGRLLLGDALPHRDRE +RLTRWMLANTTSGERFRKGLPADWLLADKTGGGRYGTNNDAGVTWPPGGGPIVLAVMTTR +SLEDAPVVDPLVAEAAALVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. GS7 TaxID=2692234 RepID=UPI001318093A +---AERELRELERRYAMRLGVYARNVRTGEVV-AYRARERFAMCSTFKAFAAAAVLRDQA +-RCAPLDKVIHYPPADILPNSPKTAQHVDTGMAVGDLCAAAIQYSDNAAGNLLLRQIGGP +AGLTRFFRSIGDRVSRLDRWEPDLNSALPGDLRDTTTPEAIGGSCERLTVGRALADADRE +HLVTWMKGNTTSEERFRAGLPRDWVVADKTGTGDYASAHDIGVAWTTRKTPIVLAVLSTK +ATRNAPVDNAPIAAAARIVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces cyaneus TaxID=1904 RepID=UPI000FF8AFDA +---VTARLRALEEQHGARLGVFAHNLATKQTV-RHRADERFPICSLFKTLAAAAVLRDLD +RDGEVLAKRIHYTAADLVENSKETEKHLATGMTVAELADVAIRFSDNTAGNLLLRELGGP +TAVTRFARSLGDPVTRLDRWETELNSAEPWRTTDTTSPRAIGRTYARLVLGNALNRPDRD +LLTYWLLNNTTSGNRLRAGLPKTWAIADKTGGGFYGTNNNVGIAWTENGTPLVLAVQTTK +PEQDAAPDHALIVETAALLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus innexi TaxID=290109 RepID=A0A1N6MY37_9GAMM +-eQMVHQLTALEKSANGHLGVALINTADHSII-GYRANERFPLCSTSKLMAVSALLKKSE +TDEKLLNQRVHYKQADLVEYSPITEKHIEDGMTLTELSAATLQYSDNTAMNLLLNQLDGP +ESVTTFARTLGDNIFRLDRKEPELNLVQPGDKRDTSSPQAMAESLYKLALGDALATNQRA +QLVEWLQGNTTGNASIRAGLPKNWVVGDKTGRCDYGSTNDIAVIWPTNRAPFVLVTYFTQ +PGKNAKARPDILAEATRIMIQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD52300 +----EAQIAALESKHPGRICVSILDMASGKRI-EHRAGERILMCSTFKALAAALVLARVD +KGEEKLDRRIHYKKSDLIDYSPATEPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP +QAITTFCRSIGDELTRLDRTEPTLNYDTANDERDTTTASAMLENLRRLLFTDVLTPASRS +QLAAWLITNKTGDTRLRAGLPKDWLVGDKTGTNGHGNANDIAVLWPSKRAPIIVTAYCEV +PAIAADERNAIIAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. QHH-9511 TaxID=2684468 RepID=UPI001315EDD9 +-----GEFAELERTFDARLGVYAVDTGTGREV-AYHDGERFPYASTFKALAAGAVLRTYS +--LGGMGRVVTYSTKDLVAHSPVTEKHVKTGMTLDALCDAAVRYSDNTAANLLLDQLGGP +KGLDAVLEELGDDVTHMERREPELSRWTPGSAPDTTTPRALAGDLRAFVLGDVLGPPERA +RLTHWLRTNTTGDETIRAGIPKGWAVGDKTGTGGYGARNDIAVVWPPGRAPIVMAIMSRR +AEAGAEHDDRLIARAASVAV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudoxanthomonas composti TaxID=2137479 RepID=A0A4Q1JVQ6_9GAMM +---LRKALRRIEAQSQGRLGVSVLDTASGQRA-GWRQTERFPMCSTVKFPLATAVLARID +AGTLRAEQRIVIARKDLLPYSPYSEQHIGGQVDVLTLCEAAMTQSDNAAANLLFALVGGP +AGLSAYLRGIGDAQTRSDRIEPMLNTCIPGDARDTSTPEAMTDTLQRVALGDTLSAASRA +RMQAWLRGCKTNAARLRAGLPPGWTVGSKTGSSSNGTSNDVGILWPRDAAPLVVSCFLTG +SPQDAAARDAVIANVGAAVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella hinzii TaxID=103855 RepID=UPI00114EBF4E +--DAQRQLARLEAREGGRLGVSLLDVQSGYAI-AYRADERFALCSTFKLLAVGAVLTRVA +RGEDDLSRPMRLSAADIVDYSPVTQQRLNEGMTLGQLCEAALLWGDNTAANLLLSTIGGP +PGVTAYARALGDGATRLDRLETALNEARPGDERDTTTPAAMLGNLRQLVLGDALPAPERE +RLRDWLMQCRTGQQRLRAGLPASWSLGHRTGAGGHGTCNDIGVAWPTPTTPVVISVYLTE +SPLDLPGRERVLAEAARILAH-- +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas venusta TaxID=44935 RepID=UPI0011BEDB59 +--KLLTEVERIEEQLDARVGFAAYDLETGQRW-EYNADQLFAMSSTFKTLACAALLQRVD +EGSEQLERRIKVSASDIVTYSPVTEAYADNRISLFELCEATLTTSDNTAANLILQAIGGP +QAVTEFVRALGDSVTRLDRWETELNEAAPHDERDTSTPNAMVSNLEKLVVGNALSPQSKN +QLREWLINNEVADGLFRSQIPDEWVIGDRTGAGGFGSRSITAVIWPPEREPTIVAFYITE +TDASFEERNSAIAELGSVI---- +>[subseq from] Beta-lactamase n=1 Tax=Jiangella sp. NEAU-YY265 TaxID=2293569 RepID=A0A418KTH7_9ACTN +------------RTHDVTLGVSATNLATGARI-AHRAADRFPILSVFKSIAAAAVLRDLD +--ETRLDHRVWYPPADILPSSGITAEHVDTGMTVAELCDAAIRYSDNAAGNLLLREIGGP +RGLTAFARSIGDGATRLDRWEIELNSAEPGDERDTSTPAALARTFAGLLVGDLLRPGDRR +RLRDWMLANTTSGPRFRDALPEGWRLADKTGAGDYGTNNDAGVAWNPAGEPIVIVAMSRR +SERDAVRVDAALADVARLVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas codiaei TaxID=56463 RepID=A0A2S7CYN0_9XANT +---LRTQWADIERGTGGRLGISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLRQVD +RGRLTLAQAVRIRASDMLEHAPVTKGHVGGALSVGELCRATMIYSDNPAANLLFPLVGGP +PGLTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGGALQPASRK +QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG +AKVDDAARDAALKAVAVAVREW- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hokutonensis TaxID=1306990 RepID=UPI0003659482 +---VSARLAALEEQHTARVGVFAHHLGTRKTV-VHRADELFPMCSVFKTLAAAAVLRDLD +RHGEVLYRVVHYTEADLVDGSDRTRAHLADGMTVEQLADVAIRYSDNTAGNLLLRALGGP +TAITRFARSLGDPVTRLDRWETELNSAEPDRITDTTSPRAIAGLYGRLVLGDALRRPDRD +RLTAWLLNNTTSTARFRAGLPATWTIADKTGSGDYGTANDVGIAWTEAGDPVVLAVLTTK +PTPDAPYDNQLVAETAELVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075966B4 +---ALDSIRSIEMSRGGRLGVAVLDTGSGRRL-RYRADESFAMCSTHKFLSAVAVLSLVD +QGKLALDKPVKYGKADLLDYAPVAREHVGRGMTIDELCAAATVWSDNTAANLLIELLGGP +AGWTRFARSIGDNASRLDRTEPALNSAIPGDPRDTTTPDAMLANLQQTLLGTVLSDSSRG +RLQNWMLSGTITDTLLRAGVPLTWRVGDKSGAGRNGTRNDIGIIFPPHASPILAAIYYTE +STGSLASREEVIAEVGGIIAKTf +>[subseq from] class A beta-lactamase n=1 Tax=Kosakonia cowanii TaxID=208223 RepID=UPI000B96169B +-------IARLEEKLHARIGIAVIDTASGKSV-SYRGDERFPLNSTHKALLCGALLSKVD +RGEFALNDTTQFSKETLVDYSPVTSKFVAPKMSWQQVCSAAISYSDNTAANLVAQKLGGP +QKVTALLAGLGDNVTRLDRKEPELNSAVPGDLRDTTTPLAVSHTLEKLTLGDALKPESRA +QLVQWMKDDKVADALLRASLPSGWKIGDKTGAGAYGSRSIISVVWPKKGQPIIVSVYITQ +TEATLAQSNDAIARIGKSIFE-- +>[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora hirsuta TaxID=1837 RepID=A0A5M7B8H2_SACHI +------DLAELERRYDARLGLHATNVRTGRML-VNRPDERFALCSTFKTYAVAALLRDHG +LSSGYFDKVIRYTRDDLVSHSPVTEKHVDTGMTVRELCEATMTVSDNTAANLLLRERGGP +GSIAPFARSIGDATTRLDRWETDLGTAIPGDERDTSTPAGIAAGYRALVLGDALAAPERD +QLTNWLIANTTGDKTIRAGLPPTWRTGEKTGSGDYGTRNDVGVTWTEDGTPIVIAILTSR +PKQDDERRDALLADTARAVAAH- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-1381 TaxID=1463829 RepID=UPI0004BEC6C0 +----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLGKYS +--LDGLDQRVTYTRKDLVANSPVTEKHVGTGMTLKELCDASVRYSDNTAANLLFDHVGGP +RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLDGALPAPERE +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR +ATKDAEPSDELIAEAASVVAD-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Marinobacter TaxID=83889 RepID=A0A1I4L2Y2_9ALTE +---LLEAVKTVEQRLDARVGIALYDSGTGESW-DYHGDDRFPITSTFKTLACAALLAKVD +NGTVDLDRRVIFSKDDLVTYSPVTETRVGEEMSLRELCEATMATSDNTAANLVLGAIDGP +DGVTAYARDLGDTVTRLDRTETSLNEATPGDLRDTTSPKAMVANLRKLVLGEALSKGSRD +TLVTWLKGNRVSDNLLRAAIPPDWTIGDRSGAGGHGSRSITAVLWPPHRPPLVIAIYITQ +TGASFDERNGAIRDLGGAIVKHf +>[subseq from] Beta-lactamase n=1 Tax=Actinoalloteichus hoggarensis TaxID=1470176 RepID=A0A221VY17_9PSEU +--AAQEALESLEAEFDARLGVYAIDTGTGEEV-EYRADERFAFASTYKVLAAAAVLEQNT +--LAELDELVAYDESDLVTYSPVTEGSVGTGMTLRQLAEAAVQYSDNTAGNLLFDELGGP +AGFAAALARVGDQVTVAEREEPDLNDYVPGDDSDTSTPEALATTLSSYALGDTLSPDKRE +LVTQWLIGNTTGDDLIRAGVPADWVVGDKTGAAAYGTRNDIAVVWRPDGDPIVIAILSDK +ADPEAQYDDSLIAEATSVTID-- +>[subseq from] Beta-lactamase n=1 Tax=Sphaerisporangium sp. LHW63015 TaxID=2248750 RepID=A0A366LNN7_9ACTN +--AVRRELRALEASFDGRIGAYAIDTATGRTI-GHRADERFPLASTFKAVVAAAVLHKAR +TDPGLLKRVVRWTAAEIEPNSPVTQEHVKSGLTVARLCEATVTQSDNTAGNILLKEIGGP +AGLTRYFRSLGDRISRSDRWEPEMNHWKPGEKRDTTSPAAMANDFRRLATGDALNAKDQK +RFTTWLVASKTGGNRIRAGLPSTWKVGDKTGTGGYGTANDVAVIWPPKAAPIVMAVYTSR +KPAEADADEKVLAKTATALVR-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces phaeoluteigriseus TaxID=114686 RepID=A0A1V6MS48_9ACTN +------RLRALEEAHGARLGVFAYNVRTRRSV-RHRAAERFPVCSLFKVLAVAAVLRDLD +RDGEVLARRIHFTEDDLVENSPVTEEHVLDGMTVAELCDAAIRRSDNTAANLLLRELGGP +AAVTRFARSIGDRFTRLDRWEPELNSAEPWRVTDTTTPYAIGRSYARLVLGDELAADDRR +RLTDWMLANRTSDNRFRAGLPPTWTLADKTGGGWYGANNDAGIAWTPDGTPVVLVVQVTA +PEREAAYDHELIVETTKVLA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A0P0GHP6_KLEPN +-----------------------------------RPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNDAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKH- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora pallida TaxID=145854 RepID=A0A1C6TIM4_9ACTN +-------FGALEARFGARLGVYAVDTGSGVTV-VHRPDERFAYASTFKALAAAALLDATS +--TAELGRVVRYTRDDLVPHSPVTERHVTTGMPLRDLADAAVRYSDNTAANLVLAELGGP +PGFAGHLRALGDRTTRPARTEPALNRTAPGDDRDTSTPRALATNLHAYVLGDALSAEDRA +LLTDWLRRNTTGHKLVRAGVPAGWTVGDKTGTAGFGTRNDIAVLWPPEGAPVVMAVLSSR +DVRDAKPDDALIAEATRLTID-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium zhanjiangense TaxID=1325107 RepID=A0A4Q0QPD4_9BRAD +------ELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGQADLLEYAPVAKQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSIGDTTSRLDHNEPELNRSRPGDPRDTTTPAAMAGNLRRLVLGEALSLTSRA +QLTEWIVNCKTGANRLRGGVPAGWRIGDKTGNNGKDASGDIAVVWPRPDAPILIAAYTQG +GTPSAAQIAAAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=A0A126Y456_9ACTN +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRPDELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +DAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAMTRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI0010229282 +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRPDELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +DAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAMTRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces libani subsp. libani TaxID=68044 RepID=A0A640TVZ5_9ACTN +---LASEFKKLERKYDARLGVYAVDTGTGREV-AYKDGERFSYNSTFKALAAGAVLRKHS +--PSAMDRVIKYSKDDLVATSPVSEKHVATGMSLSELCDAAVRYSDNTAANLLLEDLGGP +KRLEGVLKGIGDDVTRMERIEPKLSQWTPGDTRDTTTPRTLAKDLRAFVLGDVLDKGDRK +QLTKWLRTNTTGDEVIRAGMPKGWVVGDKTGAGTYGARDDIAVVWPPGRAPIAVAIMSNR +FKKDADFDNKLIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Marinospirillum celere TaxID=1122252 RepID=A0A1I1JB69_9GAMM +---LLAELKRIESNLDARIGFFAQDTETGKQW-EYNADQRFALSSTFKTLACAALLQRVD +EGSEQLSTSVSVSSADLVTYSPVLENYADTRITLFELCEATMTTSDNTAANLILQRLGGP +ESITNFARQLDDSVTRLDRWETELNQATPGDERDTTTPKAMVSNLEHLLLGAVLSTESRN +QLQTWLIDNQVADALFRSSVPDGWIIGDRTGAGGYGSRSITAVIWPPERSPVFVAFYITE +TEASFEDRNASIAQLGRVFM--- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Acidovorax TaxID=2684926 RepID=A0A2G6SWY7_9BURK +-qQWQQALTQIERNAQGRLGAALLDTGSGLAL-GWRQDERFAMCSTFKLPLAGWMLALVD +QGKERLDARVQYPASEVVDYSPVSGPKAGAGLTVGELCSATVSLSDNTAANLLLARHGGP +SALTAYLRTLGDTVTRLDRNEPTLNEAAVGDPRDTTTPLAMLQTMQKLVLGDALTPASRA +TLQRWLVETSTGDKRLRAGAP-GWRVGDKTGTAGSGTTNDIGVLWPQGGAPVLLTCYLTQ +SKAKPEQREAAIAEVARSAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. YIM 132580 TaxID=2691958 RepID=UPI00136D45AF +---TDRAFAELERKFDARLGVYAVDTGDGRTV-THRPDDRFAYASTCKALLAGAVLAGKS +--LPQMERLVRYGKEEIISNSPITEKHTATAMTLRELCDAAIRYSDNAAANLLFRELGGP +RGLQGALRGLGDQVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYALGSALPEEKRD +VLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAVVWPPDAAPIALAVLSRR +DSKDAERDDALIAGAAKVALGAf +>[subseq from] Beta-lactamase class A n=2 Tax=Rhizobium sp. BK333 TaxID=2512158 RepID=A0A4V3CLE7_9RHIZ +-qAADAKLAELERKHPGRICVSILDLASGKRI-EHRANERILMCSTFKALAAALVLVRVD +KGEEKLDRRIKFSKKDLVSGSPVTQARVGEPMTVAELCDAAVTRSDNTAGNVLLASFGGP +AALTAFCRTLGDDVSRLDRIETELNYDGPDDIRDTTTAAAMLENLRKLLFTDILSGASRS +QLAAWLITTKTGDARLRAGLPKNWLVGDKTGTNGYGNANDIAVIWPPDRAPIIVTAYCEI +PSIPAAARDAVIADIGRIAS--- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium oxalidis TaxID=944322 RepID=A0A512IYS0_9RHIZ +---ARARLRAIEDRLGGRLGVAVRDTGSGRAL-LYRADARFPMCSTFKVLAAAAILARVD +AGGERLERTMPYTAADLDSYAPVTEA--GRNMSLTDLCAAAVTWSDNTAANLMLRALGGP +PALTAWLRGIGDQTSRLDRTEPSLNSALPGDLRDTTAPVALAEDLERLLIGDVLSAASRE +RLEGWMVAARTGLKRLRAGLPADWAVGDKTGTGDNGTANVVAILRPPGRAPLVAAVYMTG +SGCTAEERDAAHAEIGQLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM3983 TaxID=1038867 RepID=UPI00040288B1 +------ELESYERESGGRIGVYAENLATGAKL-TWRADERFVMCSTFKASLAACVLARVD +RGEEKLAAMIPYGKADLLEYAPVAKQNLSAGMSVADMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSIGDTISRLNHNEPELNRSPPGDPHDTTTPAAMAGNLKRLVTGEALSPASRA +QLAEWMVGCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDAPILIAAYTQG +GTPNTAQIEAAFARIGRMVAE-- +>[subseq from] Class A beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A6B2W9S6_9ACTN +------DFQRLERTYGARLGIYAVNTGNGREV-AYRDTERFAYASTFKAFAAAAVLREYS +--LNGMGKVVKYSRADLLSNSPVTAKHVETGMTLRELCDAAVRYSDNTAANLLFAALGGP +KGLAAALAEAGDTATRVERREPELNEWTPGATRDTTTPRAWAANLRAFVLGDALGKDERA +QLAQWLRTNTTGDELIRAGVPKGWTVGDKTGGGGYAVRNDIAVVWPPNAAPIVMAIMTNR +GTADAPYDNKLIAESASVVVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ventii TaxID=2720606 RepID=UPI00143C8F18 +--SAASTFEQLENEFDARLGVYALDTGTGEEV-EYRSDERFAFASTFKALAAGALLAQYG +--LDGIDNVVAYDKADLISHSPVTERFTDEGMTLRDLAAAAVRQSDNTATNLLFDALGGP +TGLQAALRGVGDETTNVDRLETELNEATPGDDRDTSTPRAMAETLNEYVFGDVLDAQESD +QLVEWMTTNTTGATLIPAGVPDSWTVGDKSGAGGYGTRNDIAVLWPEEGEPIIMAVFSSR +DEEDATYDDALVARAATSA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID2119 TaxID=2690253 RepID=UPI0013689057 +---TDRAFAELERTFDARLGVYAVDTGDGRTI-AHRPDERFAYASTCKALLSGAVLAKKT +--LPQMERLVRYGKEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP +RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYTLGSALPAEKRA +LLIDWLRRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVWPPGGAPIALAVLSRR +DIKNAETDDALIAGAAKVALGAf +>[subseq from] Beta-lactamase n=1 Tax=Salinispora arenicola (strain CNS-205) TaxID=391037 RepID=A8M7Y4_SALAI +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] GPC-1 n=2 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A6B9L444_PSEAI +-eNLAQRLAALEARHGGRIGVAIHNLSTGARL-GHNTDERFLMCSTFKALLAGHILVRVD +RGEETLDRRIVVKEADLVDWSPVVEKRIGGDISIAELCEATITLSDNAAANLLLAASGGP +KAVTAFLRGLGDEVTRLDRTEPTLNYETPGDERDTTTPSAMVETLRRLLFTDVLSARSKA +QLAAWLIMNKTGDTRLRAGFPADWMTGDKTGTNGAGNANDVAVAWSPDRGAVIVAAFCEI +PGISGDERNAVIAEIGRIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia MF89 TaxID=1333853 RepID=T5KCE7_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDVRNDIAVLWPRGGASWVLTAYLQA +SAISNEQRAQVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. FT05W TaxID=2202417 RepID=A0A2V2QGM6_9ACTN +------AFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGTHT +--LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP +RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGEEKRA +VLTDWLRRNTTGDALIRAGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR +ATRGAKPQDALIARAARVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces kasugaensis TaxID=1946 RepID=A0A4Q9HJE2_STRKA +--DAARQLRDLEREHGARLGVFGWNTVTGASV-SHRGDERFPMCSTSKTPAVGAVLRDLD +HDGTFLSKIIHYTERDIERGAPVTGRNLAQGMSVADLCGAAISYSDNTAVNLLLAELGGP +TAVTRFCRSIKDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGKTYARLALGNALAAADRK +LLTGWLLANTTGDKRLRAGLPGNWRVADKTGTGSYGTANDVGIAWPPGQGPIVLSVLTTR +PDADAEADDLLIARAATVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-646 TaxID=1463917 RepID=UPI0007C51A0C +-aAVVDRLRELEQQHGARLGVFAHNVRTKRTV-EHRADELFPICSLFKTLAAAAVLRDLD +RHGEVLARRIHYTEADLVDGSDRTREHLAEGMTVAELADVAIRYSDNTAGNLLLRELGGP +TAITRFARSVGDPVTRLDRWETDLNSAEPWRITDTTTPRAIGRSYARLVLGHVLDRRDRA +LLTHWLLGNTTSGNRLRAGLPSTWTVADKTGAGFYGANNNVGIAWTPDGTPVVLAVQVTK +PERDAAWDHELIAEAAAVL---- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0000EBA8BE +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Jeotgalibacillus sp. S-D1 TaxID=2552189 RepID=A0A4R5XM31_9BACL +------GFMDLEKKYDARLGVYALDTGSNQSV-SYREEERFIYASTHKPLAVGALLQKKS +--LEDLEELITYTKEDLVNYNPITEKHVDTGMTLKELSDASIRYSDNTAANLIFNAIGGP +EGFKEVLQEIGDNTTEPERIEPDLNDVEPGETRDTSTPKALAESLQAFTLGDALPPEKRD +LLNDMLINNTTGDALIRAGVPEGWQVGDKTGAGSYGTRNDIAVIWPPEGDPIIIAILSSR +DEADAEYDDALIAEATKKALK-- +>[subseq from] class A beta-lactamase n=1 Tax=Cysteiniphilum sp. JM-1 TaxID=2610891 RepID=UPI00124881FF +--NVNNNFKALEKQYGGQLAISAIDTSNDQVV-DYHANKRMPMCSTFKLMLVAAVLNKSV +NEPKLLEKKIEYTQKDMVNYSPYTKENLGKGMTVSALCHAAM-LSDNTAANLLLKELGGL +DKLNQFARSIGDTTFRLDRYEPYLNTAIPGDKRDTTTAKAMSQSLDKIVLGNVLPAMQRD +LLIKWMQTNTTGDKRIKAGVNKSWIVGDKTGTGDYGTTNDIGVIWPNKCKPIVISVFYTQ +DKQDAKAQDVVIQKATSFAV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces pristinaespiralis TaxID=38300 RepID=A0A0M4DNU1_STRPR +-----RAFARLQREFDARLGVYAVDTGSGRTV-THRPDERFAYCSTHKALTAAAVLEHNS +--LAGLDKVVRYTRDDLVAHSPVTEKHVDSGMTLRAVCDAAVRYSDNTAANLLFDELGGP +KAFQAVLAALGDTTTHADRLETALNAATPGDIRDTSTPRALAHDLRAYALGDVLDAEKKA +LLTHWLKGNTTGDALIRAGVPDTWQVGDRTGAGAYGTRNAIAVAWPPGAAPVVIAVLSSR +ATEDAEYDDRLVARATEVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00042569BF +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces galilaeus TaxID=33899 RepID=A0A5J6EPH8_STRGJ +-----ARLRALEEAHGARLGVFAYNVRTRRSV-RHRAAERFPVCSLFKVLAVAAVLRDLD +RDGEVLARRIHFTADDLVENSPVTKDHVADGMTVAELCDAAIRRSDNTAANLLLRELGGP +TAVTRFARSIGDRFTRLDRWEPELNSAEPWRVTDTTTPYAIGRSYARLVLGDELAAHDRR +RLTDWMLANRTSDNRFRAGLPPTWTLADKTGGGWYGANNDAGIAWTPDGTPVVLVVQVTM +PEREAAYDHALIVETTKLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Salinicola halophilus TaxID=184065 RepID=UPI000DA21BB3 +--DLERELAALERRHGGRVGVALMNVATGAVA-SHRGDERFLFNSTGKVFMVAAVLARVD +SGEESLDRRIEIEASDIGEWAPITEQHIGSPMTVAALCQAAMAWSDNTAANKLIESVGGP +EPITAYLRSVGDDTTRLDRWEPELNADHEGDERDTTTPLAMMQTLNTLLLGEALSPASRH +QLAAWMIAGKTGDARLRAGMPAGWLIGEKTGTSSAGNANDIGIAWPGDRGAVIAVAYTYL +PEASKTQRDEVVAEIGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia miyunensis TaxID=282684 RepID=UPI000831B00B +--ELSGRFGALESRFGARLGVFALDTGSGRTV-EYRADERFAFCSTFKALAAGAILTTAN +--NAELDRRITYTATDLTAYAPITRQHVADGMTVRDLLDAAVRYSDNTAANLLFGLMGGP +AGFQRDLRNLGDQVTRSDRLEPMLSDATPGDPRDTSTPRAFAADLRTYVLDAALPTDNRA +LLATMLRANTTGAGLIRAGVPADWVVGDKTGNGDYGTRNDIAVLWPPHRAPLVLAVMSTR +HGHDDTYDNALIAQAANAAVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. CCBC3-3-1 TaxID=2490851 RepID=UPI0011BDDFED +-dSLSQQLASLEREVNGRIGLALLDTHTGEKL-TYRGDERFPLCSTFKLLAAAAVLRRSE +QQPDLLLQRMHWTPAEHLAYMPVTEKHQDEGMTLEALCLAALQYSDNLAGNLLLKTLGGP +AGITDFARGLGDNVTRLDRNEPALNTAVPGDLRDTTSPLAMLGNLNTLLLGSGLAPSSQE +KLASWLKGNTTGKKAITAAVPAGWIVGDKTGSGDYGTTNDVAILWRPDATPLLMAIYFTQ +QGKDARSRQDVLAKTARLAL--- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces griseus TaxID=1911 RepID=A0A2X2M8B0_STRGR +------AFEALEKEYAARLGVYAVDTGTGTTV-AHRDGERFAYASTFKALAAGAVLRRYG +--LGGLERIVTYRREDLVDHSPVTEKHVATGMSLGALCDAAVRFSDNTAGNLLFDAVGGP +RKLQAVLAGLGDEVTRMVRRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALGGPERA +RLTQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR +TAADADHDNTLIAKAASAAVT-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis azurea DSM 43854 TaxID=1238180 RepID=M2PYG6_9PSEU +--SAQADFEQLERTFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFTAGGVLQRTP +--LADLDRTVTYSQKDLVSNSPVTEKHVATGMPLRAVIDATLRYSDNTGGNLLFRELGGP +EGLNAVLRGIGDTTSHADRIEPELNDTFPGDKRDTSTPRALAVSLRAFALGNALPEDKRQ +VLVDIMRANTTGDENIRAGVP-GWPVADKTGTAEYGTRNDIGVVWPPNRAPIVISVLTDR +ATKDAKIDNALLAQATAAAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CT34 TaxID=1553907 RepID=UPI0005BAD030 +--RAERELRELEQRYAMRLGVYARNVRTGQVV-AHRAQERFAMCSTFKMFAAAAVLRDHA +-RCAPLDKVIHYPPADILPNSPKTAQHVDTGMPVGDLCAAAIQYSDNAAGNLLLRQIGGP +AGLTEFFRSLGDRVSRLDRWETDLNSAVPGDLRDTTTPEAIGGSCERLTVGRALADADRE +QLVSWMKGNTTSGERFRAGLPRDWVVADKTGTGDYASGNDIGVAWTTRKTPIVLAVLSSK +ATPKAPVDNAPIAAAARIVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Geodermatophilus dictyosporus TaxID=1523247 RepID=A0A1I5U1Y0_9ACTN +--DVSAEFAALEARFDARLGVFAVDTGSGAIL-EHRADERFAYASTIKALAAGALLTRTS +--PADLQRPVPVTPADLTTYSPVTETRVGGSMTLAELCDAAVRFSDNTALNLLLRELGGP +AGLDAALEAIGDDVTEVARTEPELNSAVPGETRDTTTPRALAGSLRAYAVGPGITEEDRA +QLLDWLRRNTTGDALIRAGVPADWDVGDKTGTGAYGTRNDVAVLTPPGRAPIVLAVMSSR +DEPDADPDDALVAEAARVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium loti TaxID=381 RepID=A0A316CNN3_RHILI +---VLPKIRRIEAKSGGRLGVACRIAGTSAQF-GYRENELFPMCSTFKTLAAALILHRVD +GGIEQLERSIKIPHNAIIANSPTTKKFAGGEMTVAQLCEAAVTVSDNGAANLLLESFGGP +PQLTAYLRSIGDSVSRLDRIEPELNESLPGDERDTISPLAMVEDYERLALGNSLSDKSRA +QLVEWLVANKTGDERIRAGLPKGWRCGDKTGTGDRGSTNDAAVIWPASGNPILMSVYLTG +TKQSLTKRNAVIASVSRTLVE-- +>[subseq from] Beta-lactamase n=2 Tax=Acidovorax sp. 99 TaxID=2135634 RepID=A0A2U1DZH4_9BURK +--AWNDALASIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD +QGKERLDARVHYPATDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDEVTRLDRTEPTLNEAAVGDPRDTTTPLAMLQTLQKLVLGNALSPMSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPQGGAPVLVTCYLTR +SIAPPEQRDAAIAQVARAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. LVM 105 TaxID=2341115 RepID=A0A5E8VJA4_9BRAD +----PAELESYERESGGRVGLYAENLATGAKL-SWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMVPYGKADLLEYAPVARQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSIGDNTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVVGDALSPASRA +LLTEWMVNCKTGANRLRGGLPASWTIGDKTGNNGKDAACDIAVVWPKPDTPILIAAYVQG +GAPNAAQIEAAFARIGRTVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Sediminibacillus massiliensis TaxID=1926277 RepID=UPI0009883A71 +--NTDDKFAQLEDDYNARLGVYAIDTGSNQTI-EYRSDERFAFASTYKALAAAILLQQKT +--MEELEKVITYTADDMVPYSPVTEKHMDTGMTLFELAEAAVRTSDNTAGNLLLNALGGP +DGFEEALRQAGDNITQSDRYETELNEFKPGDIRDTSTPKALATNLQAYAVSDMLSDEDRE +RFTNWLQGNATGDTLIRVGAPDGWTVGDKSGAGSYGTRNDIAVVWPPNREPIVMAIMSRH +NTEDAKYDDGLIAKAAKIALK-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00037B1422 +--DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQADQRFAYGSTFKALAAAEVLDATT +--DAELDQVVWYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEQELKGIGDNVTDAARYETELNEAIPGDRRDTSTARALTEDLREYAVDDALDPTDRD +LLNAWLRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEADASFDNALIAEAAKVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007F11E8D +-nDVQQKLAALEKSSGGRLGVALIDTADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA +QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGREA--------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. QL37 TaxID=2093747 RepID=A0A2S6PH06_9ACTN +-----PAFRELERKFDARVGVYAVDTGSGLSL-THRPDERFAYASTCKALLAGALLDRYT +--LQRLDRRVRYGPEELVANSPVTERHVDTGMTLRELCDTAVRYSDNAAANLLFHELGGP +RGLKDALLALGDRTTRCDRYEPDLSEAAPGDPRDTSTPRALAADLRAYVLGGTLGTDKRA +VLTDWLKRNTTGDALIRAGAPDGWVVGDKTGTGGYGTRNDIAVLWPPESAPIVLAVLTRG +NARGAEPQDPLVAQAARVALTAf +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. 4(2017) TaxID=1404402 RepID=UPI001408E54E +------ELESYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARAD +RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVVGEALSPASRT +QLTEWMVGCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPKNKAPILIAAYTQG +GTPNAAQIEAVFARVGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. Nf4 TaxID=2116542 RepID=A0A2T3WUA6_9GAMM +----ASDFAALERACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPEMNRFAEGDPRDTTTPAAMAGSLQRVVLGQVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLRA +GQISYEQQAAVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0012AB4E6D +----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS +--NEKLNAIIRYSKDDLVTYSPITEKHMDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP +KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT +ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVW---RAPIVLAILSNR +FTEDANYNNALIAEAAKVALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces kasugaensis TaxID=1946 RepID=UPI000B9E62B9 +--DAARQLRDLEREHGARLGVFGWNTVTGASV-SHRGDERFPMCSTSKTPAVGAVLRDLD +HDGTFLSKIIHYTERDIERGAPVTGRNLAQGMSVADLCGAAISYSDNTAVNLLLAELGGP +TAVTRFCRSIKDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGKTYARLALGNALAAADRK +LLTGWLLANTTGDKRLRAGLPGNWRVADKTGTGSYGTANDVGIAWPPGQGPIVLSVLTTR +PDADAEADDLLIARAATVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces celluloflavus TaxID=58344 RepID=UPI000DA63C33 +--DAARQLRDLEREHGARLGVFGWNTVTGASV-SHRGDERFPMCSTSKTPAVGAVLRDLD +HDGTFLSKIIHYTERDIERGAPVTGRNLAQGMSVADLCGAAISYSDNTAVNLLLAELGGP +TAVTRFCRSIKDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGKTYARLALGNALAAADRK +LLTGWLLANTTGDKRLRAGLPGNWRVADKTGTGSYGTANDVGIAWPPGQGPIVLSVLTTR +PDADAEADDLLIARAATVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000EFC5438 +-hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD +KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP +PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA +QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDIAVAWSPNRGAIVVATYCEI +PTISADERNAVVAEVGRLVAE-- +>[subseq from] class A beta-lactamase n=3 Tax=Rhizobium meliloti TaxID=382 RepID=UPI0001E4C4B9 +-hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD +KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP +PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA +QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDIAVAWSPNRGAIVVATYCEI +PTISADERNAVVAEVGRLVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Kushneria konosiri TaxID=698828 RepID=UPI000A3AF19A +-qKIQDRIQALEAQHGGRLGVALMNVGTGAVV-SHRGDERFLFNSTCKVVIAAALLAQVD +NDKASLDQRIEVKASDLTGWTPITEQKLGSPMTIAELCQAAVAWSDNAAANLLIERLGGP +ESVTAFLRNIGDATTRLDRTEPALNEDHQGDERDTTTPLAMMQTLQTLLLGDALSPSSRH +QLAAWMIEGKTGNARLRAGMPANWLIAEKTGTNSVGNAADIGLAWTPDRGAVIAIAYVYL +PEADKAQRDQVIADIGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium symbiodeficiens TaxID=1404367 RepID=UPI00140FD866 +------ELETYERESGGRIGVYAENLTTGKKL-TWRADERFVMCSTFKASLAACVLARVD +RGEEKLAATIAYGKADLLEYAPVAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALTPTSRA +LLTEWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVAWPKPETPILMAAYTQG +GTPNAAQIEAAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces spectabilis TaxID=68270 RepID=A0A516R262_STRST +---YARAFKKLERKFDARLGVYAVDTGTGREV-AYNDSRRFAYNSTFKALAAAEVLRQYA +--PDRLDQVVKYSKDDLIANSPVTEKHVDTGMTLRALCDAAVRYSDNTAANLMFDKLGGP +KGLDAALERIGDDVTRMDRVEPFLSRWVPGEKRDTSTPRALAKDLRAYVLGDALAAPERT +QLATWLKTNTTGDHVIKAGVPKNWVVGDKTGTGSYGARNDIAVVWRPGAAPLVVAILSHR +GDKDAAPDDKLIAEAASVVA--- +>[subseq from] Beta-lactamase CTX-M-2 n=1 Tax=Xenorhabdus cabanillasii JM26 TaxID=1427517 RepID=W1ILU4_9GAMM +--QIINQLVALEKSANGHLGVFLINTADNSTI-GYRANERFPLCSTSKFMTASALLKKSE +KDGNLLNQRINYKQSDVVEYSPITEKHVESGMTLAELSAATLQYSDNTAMNLLLDQLDGP +RGLTKFARTIGDNEFRLDRKEPELNLVKPGDERDTSTPQATAKSLYKLTLGNVLATNQRV +QLVEWLKGNTTGDASIRAGVPKDWVVGDKTGLCDYGSTNDIAVIWPTNRAPLVLVTYFTQ +PGKNAKARRDVLAEATRILTQ-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 1114.5 TaxID=1938830 RepID=A0A495SSF0_9ACTN +--DTHRRLSALEQQHGARLGVFARNLSTGRTV-RYRAGELFPICSVFKTVAVAAVLRDLD +RDGKFLAKRIHYTEADIKRGAPVTGENLANGMTVAELCKAAIDHSDNTAGNLLLRELGGP +TAVTDFCRSIGDHVTRLDRWEPELNTAEPDRTTDTTSPQAIARTYRRLTLGHALPPAKRD +QLTTWLRGNTTSIHRFREGLPQDWALADKTGSGQYGTANDVGIAWTPSGAPVVLAVLTTK +PDEAAPKDEPLVAETAALLA--- +>[subseq from] Beta-lactamase n=1 Tax=Nitrincola nitratireducens TaxID=1229521 RepID=W9UVN9_9GAMM +--ALMTELQRIENVLDARIGFSAYDSETGVRW-EYNADQRFAMSSTFKTLACAALLQRVD +SNQEQLERTVSFSKSDLVTYSPITEQHADNRMSLFELCEATMTTSDNTAANLILQAMGGP +GVVTEFAREIGDNVTRLDRWETELNQATPGDDRDTTTPNAMVANLKGLLLGDVLSPNSKS +QLREWLVGNKVADGLFRASMPAEWIIADRTGAGGFGSRAITAVIWPPERLPIVVAFYITE +TTASFEDRNTAIAELGRVI---- +>[subseq from] class A beta-lactamase n=1 Tax=Gallaecimonas mangrovi TaxID=2291597 RepID=UPI000E1FEC27 +--SFADALSELEIQHGGRLGVAAFNSADGNRL-AYRADTRFAMCSTFKAVLAGAILQKVD +SGQLKQQSPVRYDASELLDYAPVTRLHLADGMTVAALAKAAVTLSDNTAANLLLKVIGGP +QALTAFYRQLGDSTSRLDRFEPSLNSNEPGDVRDTSTAAATLHSWRQLLLGKALLPASRQ +QLLRWLKDSQTGQDRIRAGLPQGWQVGDKTGSCENGGTNDIAIVWPANTPPYLLAIYYSD +GLGSSAQKNRVLAEVSRLVAKRf +>[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. 2251 TaxID=2560053 RepID=A0A4Y5SSU7_9RHOB +--TVTEAARAIEADLGGRVGVSLRQPGGSDAT-GYREDERFPLSSTFKVPLCGTILTLVD +AGEDQLDRRVGYSPGDLVTYSPVTETR--DAMTVAELCEATITLSDNTAANLLLDRLGGP +EDFTQYLRAIGDDTTRLDRWETDLNEAVPGDPRDTSTPAAMTATLETLLFGPVLSVASQQ +QLEAWMRADQVADDLIRASLPEGWVIGDKTGAGGYGSRSIIAVIRPPQGDPWLTAVYLTG +NEADMPTRNRAIARIGAALVS-- +>[subseq from] Beta-lactamase n=1 Tax=Kushneria konosiri TaxID=698828 RepID=A0A2Z2HB39_9GAMM +-qKIQDRIQALEAQHGGRLGVALMNVGTGAVV-SHRGDERFLFNSTCKVVIAAALLAQVD +NDKASLDQRIEVKASDLTGWTPITEQKLGSPMTIAELCQAAVAWSDNAAANLLIERLGGP +ESVTAFLRNIGDATTRLDRTEPALNEDHQGDERDTTTPLAMMQTLQTLLLGDALSPSSRH +QLAAWMIEGKTGNARLRAGMPANWLIAEKTGTNSVGNAADIGLAWTPDRGAVIAIAYVYL +PEADKAQRDQVIADIGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodoligotrophos appendicifer TaxID=987056 RepID=UPI00117DF5D0 +--TMDDRLRDVEARNGGQLGVAILDLASGHVF-GHRADERFPLLSTVKLLAAAHVLARVD +RGQERLDRRVIFSKRDLVTYSPMTEGRVGAPMTMAELCDAAIATSDNTAGNLLLASAGGP +AGLTRFLRSIGDEVTGLTRIEPFLNSAVPGDLHDTTTPRAMLETMRKLLVDDGLSETSRR +QLAAWLVANKTGDKRIRAGIPKTWRVGDKTGTNQM-GACDVAIVWPPARKPILVTVYYAS +KPQTAESRDAVIAAVGRLVA--- +>[subseq from] class A beta-lactamase n=2 Tax=Curtobacterium flaccumfaciens TaxID=2035 RepID=UPI000FFE44B7 +--ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTVKVFIAAAVLDASS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVEQLGGP +DAVERWLRGIGDRTTRVDRVEPDLNEATPGDPRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR +ADPGAEPSDALVAAATRTAV--- +>[subseq from] Carbapenem-hydrolizing beta-lactamase SFC-1 n=2 Tax=Serratia fonticola TaxID=47917 RepID=UPI0002604937 +-----DKLKRLENDFGGRIGVYAIDTGSNKTF-GYRANERFPLCSSFKGFLAAAVLSKSQ +QQEGLLNQRIRYDNRVMEPHSPVTEKQITTGMTVAELSAATLQYSDNGAANLLLEKIGGP +EGMTSFMRSIGDNVFRLDRWALELNSAIPGDDRDTSTPKAVAESMQKLAFGNVLGLTERH +QLMDWFKGNTTGGARIRASVPANWVVGDKTGTCGYGTANDYAVIWPVAHAPIVLAVYTSK +PDRNSKHSDAVIADASRIVLESf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. LaPpAH-199 TaxID=1265493 RepID=A0A1G6MLD6_9ACTN +----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLGKYS +--LDGLDQRVTYTRKDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLDGALPAPERE +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR +ATKDAEPSDELIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia crassostreae TaxID=53428 RepID=UPI00082A6E6D +--AATSRFADLETKAGARLGVYALDTGSGHTV-SYREGERFPMASTFKGLACGGLLRDHS +LASGYFDQVIRYPASDLVEFSPETEKHVEDGMTVSALCDAAITLSDNTAGNQLLKLLGGP +AGFTAFLRSIGDDVSRLDRWETELNTAIPGDERDTNTAAALVSDYRKLVLGDLLGQAERK +RLQDWLIASTTGGKRIRAAMPGHWVVGDKTGSPAYGSALDVAIAWPPNSAPIVIAVLTTK +PQQDAKPDNDLVADAARVALETf +>[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium kowhaii TaxID=1300272 RepID=A0A2W7DSD9_9RHIZ +------KMRRIEVKSGGRLGVACRISGTTAQF-GYREDEPFPMCSTFKALAAAFVLHRVD +GGIEQLDRSIEVPHDAIIANSPTTNKHAGGEMTVAQLCEAAVTVSDNGAANLLLESFGGP +PQLTAYLRSIGDKVTRLDRIEPELNESLPGDARDTTSPLAMVNNLERLTIGNSLSGKGRA +QLVDWLVANKTGDARIRAALPKGWTCGDKTGTGARGSTNDAAVIWPTSSNPILMSIYLTG +TKQSLAKRNAVIASVSRALVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax delafieldii TaxID=47920 RepID=UPI00076AB79B +--AWNEALASIERTAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD +QGKERLDARVHYAAADVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDPITRLDRTEPTLNEAAVGDPRDTTTPLAMLQTLQKLVLGNALSPMSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTAGSRTANDIGVLWPQGGAPVLVTCYLTR +STASGEQRDAAIAQVARAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0003A66027 +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAVADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00039F9936 +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAVADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Curtobacterium TaxID=257496 RepID=UPI000D9214D4 +--AAERAFAALETEHDARLGVVAIDTGSGVGV-AHRADERFAFASAAKVFIAATVLDAAA +--PDDLDAVVPIGQGDVLSYAPVTGQHVGSGMTVRALLAAMVRSSDNTAANLLVARVGGP +AAVQRWLRGIGDDVTRVDRVEPDLNEAVPGDERDTTTPAQFAADLRTVLLGGALDPDDRA +LLVDLMRGTTTGAGTIRAGVPEGWTVADKTGTGSYGVRNDVGIVTPPGRDPIVLVVMTGH +DTADAEPDDALVAAATRTAL--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudovibrio axinellae TaxID=989403 RepID=A0A165SXE3_9RHOB +--QLLETVAKLEADVGGRIGVVVRHTGSDWSI-EHRPNERFPMASTFKALLCGGVLARVD +QGQENLENVARYTADELVRYSPVTEKHVATGMSVGDLCEATITVSDNSAANFLLKRLGGP +EGFTRFMRGIGDEDTRLDRWEVEMSESKPGDLRDTTTPEAISKSLGKLLFGDILQPHSRE +LLTHWMINNKVADALMRKHLPTGWRIADRSGMGHYGTRGNIAALWTETGEVYLAAIYMTG +SDADVKTRNATIAEVGQAIF--- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0004764019 +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAVADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=Q59923_STRLA +--RVARALAELEREHGARLGVYALETDTGRTV-THRADELFPMCSVFKTLAAAAVLRDLD +HDGSVLARRIHYTQADIDRYSEWTKRHLANGLTIGELCEVSITYSDNTAANLLLRELGGP +AAVTRFARSLGDPVTRLDRWEPELNSAEPDRVTDVTTPRAIARTYARLVLGDGLGRADRG +LLTGWLCANTTSGARFRKGLPAEWRLGDKTGGGSYGTNNDVGIAWRPHGAPLVLAVLTTK +PAQDAKADDALVSGTARALAGAf +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SVU4_9BACT +-----EAARQAEAQLDARVGLAVYDTGSGANW-LFNADGSFPMGSTFKVLACGVLLARAD +AGDEDLDRFVEIVQTDLVTYSPVTETWVGRNVSLGEICAATMRTSDNTAANKVLEALGGP +GSLTAFLRSLGDQTTRLDRWETDLNEGTPGDPRDTTSPAAMAASFQKFVLGDVLSTSSRE +TLTDWLLGNEVGGPLLRAGLPEDWRIGDRTGAGGHGSRGIVAVLWPPGRAPLIAAIYLTE +TQATLEGRDAAIAAIGRAIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Lentzea sp. FXJ1.1311 TaxID=2591470 RepID=A0A563EGR9_9PSEU +-----DRLAELERKFDARLGVYVLDTGSGATI-VHRPDERFAFCSTFKGVAAAAVLHRNP +--LSHLDTVVRYTEADLMEHVPVTGQHVATGMKIRDLCDAAIRHSDGTAGNLLVRDLGGP +AQLTDFVRGLGDTVTRMDRIEPAITEATPGDPRDTTSPRAFGTTYQKIVLGPTLPDDKRA +FLRDLLERNTTGDQRIRAGVPQGWVVADKTGTGSYGTLNDIAVVWPPNAAPLIISIMSSK +AAKGAKADQAVIAEAAARVV--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=A0A4U3GH03_9GAMM +--STARDFATLEAASGGRLGVTLLNTGSGQRI-GHRQDERFPMCSTFKFALCATVLRLAD +QGKLSLDRRLAMTTQDLLSHAPVTARHVGKDVTVRDLCRATMVTSDNPAANLLLRVVGGP +AGVTAFLRASGDDVTRNDRYEPEVNRFAPGDPRDTTSPAAMAASLQRLVLGELLQPASRQ +QLADWLIDNETGDAHLRAGLSNAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ARLDGAGRNDVLRQVAVIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis quinghaiensis TaxID=464995 RepID=UPI00123AF155 +---MDSEFAHLEEEFDARLGVYALDTGTDRAV-GFQADERFAYCSTFKVLAFGAVLDRTP +--VDELDRVVTFSGADLVFHSPVTREHVSTGMTLREIGDAALRHSDNTASNLLFEELGGP +QGLDEALREIGDDVTSVDRIAPEMAEAVPGDVRDTSTPRAMATSLREFALGDVLSEDKRG +VLVEMMRANTTGDDLIRAGVPEGWEVGDKTGACGYGTRHDIGVLWPPEGAPIVLAVMSGR +DEAGAEYDDALIARATEMVV--- +>[subseq from] Beta-lactamase n=1 Tax=Thalassobacillus cyri TaxID=571932 RepID=A0A1H4G6Q8_9BACI +---TDKEFTQLEREFDARIGVYAMDTGTDQTV-EYCPDEHYAYSSTFKVLAAAILLKQND +--IEKLKKIVTYTKDDLVTYSPVTEKHVDTGMTMLEISEAAIRTSDNTAGNLLLEAIGGP +EQFKQALRDMGDDVTMPERYETELNEFTPGNKRDTSTPRVIATNLEKVALGDFLPDDKRE +LLIDWMKGNQTGDSLIRAGAPQGWRVDDKSGAGSYGTRNDIAVVWPPNREPIVIAVMTRY +DTKNAEYDDSLVARAAEITLD-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. campestris TaxID=340 RepID=O87643_XANCE +--MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD +KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP +PGLTRFLRGIGDTKTRSDRLE-AMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK +QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG +ATVDAAARDAALKAVAEAVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID3343 TaxID=2690260 RepID=UPI00136ACC65 +-----GQLSEIERQHGARLGVFACNTATGATV-AYRAGERFPMCSVFKATAAAAVLRDLD +RDGEGLARRIRYGDKDVADYAPITSRNLAGGMIVADLCAAAIAYSDNAAANLLLRELGGP +AAITRFCRSVGDGTTRLDRWEPALNSAEPWRATDTTSPRAIGRTFARLTLGDALAPSDRK +RLTGWLLANTTGDARLRAGLPAGWALADKTGTGGFGTTNDVGIAWTPNSTPIVLAALSTK +QDADAPADEPLMAKVAALVA--- +>[subseq from] Beta-lactamase n=1 Tax=Sinobacteraceae bacterium TaxID=1969813 RepID=A0A522ZKT7_9GAMM +--DYAAQLAELERVHGGRLGVAILDTGNGRYI-AHRADERFLMCSTFKLLLAAAVLARVD +HGVEELDRRVMFDKATLLDWSPVTQLYAGPPMTVAALCQAAITMSDNTAANLLLASSGGP +AAVTRYARSLGDTLTRLDRSEPTLNHA--DGEKDTTTPRAMLGDIHKLLLGDALAASSRG +QLVDWLQHCQTGAASLRAGLPADWRTGDKTGSGV-AATNDVAILWPPARKPLLVTAYYDN +GQLPASERRAVLAEVGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora purpeofusca TaxID=67352 RepID=UPI0007C4CD52 +--ELADRFRALERSHSARLGVFAQDTVTGRTV-AHRADELFPMCSTFKTIAVAAVLRDLD +RDGTFLAQRRLYTATDVAQYAPITGLNLEAGLTVEELCAAAIRYSDNAAANLLLRELGGP +DALTRFCRSIGDRVTRLDRWEPALNSAEPSRLTDTSSPHALGRTYARLALGATLDPADRQ +RLTGWLLTNTTGTNRLRAGLPPTWHVAEKTGTGSYGTTNDVGVTWRPDGRPIVVAVLSTK +HTADAPADEPLIAETARIVAT-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ADI96-02 TaxID=1522760 RepID=A0A3N6ETQ7_9ACTN +-----RAFRALEAKYGARLGVHAVDTGSGRVV-AHRDRERFAYASTFKALAAGAVLRKHG +--LEGLERTVRYGREDLVDYSPVTEKHVDTGMSLGDVCDAAVRYSDNTAGNLMFDALGGP +RGLQAMLAELGDDVTRMERRETELNEWAPGAIRDTSTPGALAGSLRAFVLGDALEGPERA +RLTTWLRTNTTGGELIRAGVPKDWVVGDKTGAGSYGTRNDIAVVWPPGAAPLVVAVLSNR +GTADAAYDNALIADAAAVAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Geodermatophilus dictyosporus TaxID=1523247 RepID=UPI000B807880 +--DVSAEFAALEARFDARLGVFAVDTGSGAIL-EHRADERFAYASTIKALAAGALLTRTS +--PADLQRPVPVTPADLTTYSPVTETRVGGSMTLAELCDAAVRFSDNTALNLLLRELGGP +AGLDAALEAIGDDVTEVARTEPELNSAVPGETRDTTTPRALAGSLRAYAVGPGITEEDRA +QLLDWLRRNTTGDALIRAGVPADWDVGDKTGTGAYGTRNDVAVLTPPGRAPIVLAVMSSR +DEPDADPDDALVAEAARVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Pseudoxanthomonas TaxID=2645906 RepID=UPI000F62A280 +----APDFAALEAASQGRLGVAVLEAGNGRYLaGHRADERFPMCSTFKALLAAAVLARAD +RGALDLDERLPVRAADLVPHAPVTRRHVGKDLGVRDLCRAIVTISDNTAANLLFARIGGP +AALTAFLRGLGDTVTRSDRLEPEMNGFVPGDPRDTTSPRAMATSLGRCVAGAVLAPASRL +QLADWLIDNTTGDDCLRAGIGPEWRVGDRTGSNGTDIRNDVAVLWPLGGSPWVVAAYLEG +SRVDSAARDAVLARAGQLAV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces iranensis TaxID=576784 RepID=A0A061A8X6_9ACTN +--AATGEFKKLERSYDAHLGVYAIDTGTGHEV-AYRDGERFAFASTFKALAAGAVLRKYK +--LSGLDRVIRYSKDDLVDYSPVTEKHVDTGMSLGALCDAAVRYSDNAAANLLLDELGGP +KGLDATLEKLGDDVIQMENIEPELSRWVPGETHDTSTPRAMAKDLRAFVLGDVLGKGERA +QLTKWLRTNTTGDELIRAGMPKGWQVGDKTGNGSYGARNDIAVVWRPDAAPLVVAIMSYR +GDKDTPFDNKLIADAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora endolithica TaxID=230091 RepID=A0A3A9ZJY6_9ACTN +------DFTPLEAEFDARLGVYAVDTGTGRTV-AHRADERFAYASTFKALAAAAVLDATT +--TAELDEVVTFTRADLVAFSPVTGRHVDSGMTLRAVADAAVRHSDNTAGNLLLDRLGGP +AGFERDLRELGDEVTEPARRETALNEAAPGDVRDTSTPRALATTLRAYAVGDALDVGDRA +VLVDWLRRNTTGAKLIRAGAPDGWVVGDKTGTGGYGTRNDIAVLWPPDRAPIVLAVLSRR +DARDADHDDALVARAAEVTL--- +>[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus sojae TaxID=582851 RepID=UPI00098844BB +----EEAFKELEDEFDARLGVYAIDTGSEQTV-TYRSDERFAYASTFKALAAGAILQTNS +--IEDLEKVITYSEEDLVTYSPVTEKHAGDGMKLEEIIEAAVRYSDNTAGNLMLEELGGP +DGLEGILRKNGDETIEMDRMETELNEAVPGDKRDTSTPQALAESLQKYVLSDLLPEDKRE +LLIDWITGNEAGDSLIRAGVPEGWEVGDKSGAGSYGTRNDIAVVWPPDNAPIVIAVLSSQ +DTVDADYHDELIEKAAERVME-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis rhizosphaerae TaxID=2053003 RepID=A0A558CTQ5_9PSEU +----QQDFERLERTFGARLGVYAVDTGTGREV-AFRAGERFAYASTHKVFSAGAILQRTP +--VEGLDRTVMFGQGDVVSYSPITQKYAGTGMPLRAVLDAALRYSDNTAANLMFRELGGP +AGLTDALRAIGDTTTSPDRIEPALNEAVPGDPRDTSTPRAMAADLRAFTLGTALPEDRRA +VLVGMMRANTTGATLIRAGVPADWQVADKTGAASYGTRNDIAVVWPPQRAPIVLVVLSDR +QAKDAAYDDKLIAQAATSAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. CA-128772 TaxID=2073159 RepID=UPI000CD10927 +-----PDFAPLERDFDARLGVYALDTGSGREL-THRADERFGYASTHKVFSAAAVLQRTG +--LDGLAKNLTYTRADLQPNSPVTEKHVATGIPLRDAIDAALRYSDNTAANLLFRELGGP +AGLAQALRGIGDTTTYVDRIEPGLNDLAPGDVRDTSTPRAMAGSLRAFTLGAALPPEKRT +VLTDMMRANTTGAALIRAGAPAGWAVADKTGTGSYATRNDIAVVWPPGRAPIVLVVMSSR +PAKDADHDDRLIAQAAKLVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Terriglobus roseus (strain DSM 18391 / NRRL B-41598 / KBS 63) TaxID=926566 RepID=I3ZLG6_TERRK +--ALPTAIAAMEKKNGGRIGVSLLDTATGERA-AWRADERFPMCSTFKFLLAAAVLHRVD +TLKDDLRRQVDVPPKPLLGNSPLTAEHAGTSMTLGALCSAILIRSDNTAANVLLETIGGP +GKITTYAQSLGDTVTRLDRTETALNESLAGDPRDTTSPDAMVHNLQSLLLGDALKPDSRQ +QLLDWMQSSTTGLTRIRAKLPKGWRAADRTGSNGEHTTNNIAVLWPNGGAPLIVAAYITQ +CPGSEDKRNAMLAEIGRLVAA-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000DA98378 +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. YC537 TaxID=1775135 RepID=UPI001378DA9C +---YSRELKALERKFDARLGVYAIDTGTGREV-AYNDKERFLFASTFKALAAAAVLDKHS +--DRDMERVVTYDKSDLVENSPVAEKHVDSGMTLNELCDAAVRYSDNTAANLLFEDLGGP +RALDATLAGLGDDVTRMERIEPDLSDWEPGNDRDTSSPRALAADLRAYVLGDALDRGDRD +RLTKWLRTNTTGGALIRAGMPKGWTVGDKTGMGNYGIRNDIAVVWRPDAAPLVVAVLTNR +HKPGDKHDDKLIADAAEVVAD-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6B8I7B1_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=UPI000BAA9A6A +-dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDRFPMMSTFKTLMCANALYLAE +QKKLNLNATTKVKESDLVTWSPITEKLIGQEITVQKACEATMLMSDNTAANIVLHQIGGP +EQVSQFVRSLDDKVTRLDRFEPELNQAIPGDKRDTTSPSAMVELLNTLLLQDGLNQESQQ +QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPVILSIYLTQ +TQLDMAQRNRVINRVANLVFEQf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TLI_185 TaxID=2485151 RepID=UPI000F51558F +-aAAVDRLRELEQQHGARLGVFAHNVRTKQTV-EHRADELFPVCSLFKTLAAAAVLRDLD +RHGEVLARRIHYTEADLVDGSDRTREHLAEGMTVAELADVAIRYSDNTAGNLLLRELGGP +TAITRFARSIGDPVTRLDRWETDLNSAEPWRITDTTTPRAIGRSYARLVLGHVLDRRDRA +LLTHWLLGNTTSGNRFRAGLPKTWTVADKTGGGSYGANNNVGIAWTPDGTPIVLAVQVTK +PDQDAELDNPLIAGTAAFLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium durans TaxID=2202825 RepID=A0A2U8WEG0_9RHIZ +----RQSLRVIEDRLGGRLGVAVRDTSSGRAL-LHRADARFPMCSTFKVLAAAAILARVD +AGRERLERTMPFTAADLDSHAPVTK-EAGGEMSLADLCAAAVVWSDNTAANLMLQALGGP +PALTAWLRGIGDQTSRLDRTEPTLNTAIPGDPRDTTSPAAIAEDLERLLIGDVLSPASRG +RLEGWMVAARTGLKRLRAGLPQDWAVGDKTGSGDNATANVVAILRPPGRAPLVAAIYLTG +SISTAEERDAAHAEIGRLVAVTf +>[subseq from] Beta-lactamase n=1 Tax=Lysobacter capsici TaxID=435897 RepID=A0A291A5M4_9GAMM +---WRTRLRDLEKHSGGRLGVAVLDTGNGERM-LWRENERFRMCSTFKYLLAAAILRQVE +LGKVALSQQVPITAADMISHAPFTQPLVGRSASVAQLCEATVTLSDNPAANLLYPLVGGP +QGLNRFLREIGDGVTRTDRTEPTLNSGAPDDPRDTSTPSAQIATMQRLLLGDALKESSRQ +QLIAWLVANKTGDKRLRAGLPAGVRVGDKTGSGDD-ATNDVAIVWPPGRAPLLIVSYLAT +TKLDGAGRDAVLASLARIASEHf +>[subseq from] Class A beta-lactamase n=1 Tax=Labrenzia sp. VG12 TaxID=2021862 RepID=A0A222F0Q1_9RHOB +-------VLDAEKRLSARVGVSVIDLETGTRW-QNRADERFPTNSTFKTFLCAAFLDAGA +RGAVDPDRAIVIRQSDIVSYSPVAKEKVDGAVTLRELCATTVTISDNAAANLVMKELGGP +EAVTAYLRSIGDEVTRVDRWEPDSNSGIPGDARDTTSPNAAAETLKKLVLEETLPDAERR +LLTKWLVGNKVGDATLRAGLPEGWRIADKTGAGANGSRNNIAVIWPEGRKPVVIAIYITQ +TAASFKARNAAIADIGQALA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. SUTN9-2 TaxID=1167456 RepID=UPI000D65C147 +-----SEFESYERESGGRIGLYAENLATGKKL-SWRADERFVMCSTFKASLAASVLARVD +RGEEQLAAMIRYGQSDLLEYAPVARENLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSQPGDPRDTTTPAAMAGNLRRLVAGEALSPASWA +LLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYTQG +GTPSAAQITSAFARIGRMVAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID13031 TaxID=2706046 RepID=A0A6B2U1K9_9ACTN +--QVTEPFSKLEKQYSARLGVFAYDTGTHRTV-SYRAGERFPHASTFKALACGVLLIETK +----NLDKLIRYDESILLPNSPITEKHVATGMTLRELCDAAIRYSDNAAANLILAEIGGP +SGLQRALRRLGDVVTNTSRTEPTLNEATPGDTRDTTTPRALATSLQKLTLGHALPPAKRA +VLVGWLKANTTGGTTIRAGVPKDWTVGDKTGTAAYGGRNDVAILWPPNRAPIMLAILSTK +GAKDAVPNDALIAAAAAAAIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-24051 TaxID=1463832 RepID=UPI0004C8C8FD +-----RAFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGMHT +--LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP +RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEKRA +VLTDWLRRNTTGDALIRAGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR +ATRGAKPQDALIARAARVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Gammaproteobacteria bacterium DM2 TaxID=2169539 RepID=UPI000D3E8B69 +--PLQKEFASLEQSAHGRLGIYAINTGNAQEL-GYRADERFPLASTFKVIAVSDLLQKSV +TAPELMQHKVNFNKKDLVNYSPITGKHLESGMTYAELSAAALQYSDNTAGNLIVKQLGGP +SEVTLYARQIDDQEFYLERWETELNSATPGDVRDTTTPKAMAITLKRLAFKDVLPKAQRR +QLLEWMKGNTTGDASIRAGLPHGWTVADKTGGGSYGSTNDIAVIWPKRKAPWVIAIYFTQ +SKQDAPLRKDVIAAATRLIVKQw +>[subseq from] Class A beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A6B1L8F4_9ACTN +------AFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGMHT +--LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP +RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEKRA +VLTDWLRRNTTGDALIRAGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR +ATRGAKPQDALIARAARVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. S501 TaxID=2420135 RepID=A0A4V1B2K8_9ACTN +------AFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGMHT +--LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP +RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEKRA +VLTDWLRRNTTGDALIRAGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR +ATRGAKPQDALIARAARVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-325 TaxID=1463899 RepID=UPI00056D076B +------AFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGMHT +--LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP +RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEKRA +VLTDWLRRNTTGDALIRAGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR +ATRGAKPQDALIARAARVAL--- +>[subseq from] Beta-lactamase n=2 Tax=Gracilibacillus orientalis TaxID=334253 RepID=A0A1I4JZW9_9BACI +----DEEFAQVENEFDAQLGIYAIDTGKNQIV-EYNPDERFAYSSTFKVLAAAILLKQNE +--IEELEKVVTYSEDDLVTYSPVTEKHVDTGMTLLEVSEAAIRKSDNTAGNLLLEALGGP +DKFEQALRDIGDDITEPERYETELNEFTPGSKSDTSTPRAMATNLKKVALGDFLPSNKRD +LLVEWMKGNATGDALIRAGQPEGWIVGDKSGAGSYGTRNDIAIVWPPNRAPIVIAVMSKH +DSKDAEFNNELVAKAAEITL--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. DJ TaxID=2067551 RepID=A0A2N5XF65_9ACTN +---TAAQLRRLEARHRARIGAFAHNLATGATV-LHRAHDRFPLCSVFKPLAAAAVLRDLD +RDGEVLAERIRYTEADVVADSPVTDEHLATGMTVGELCDAAVRHSDNTAGNLLLRRLGGP +SAVTRFCRSTGDTVTRLDRWEPELNSAEPWRVEDTTTPYAIARTYARLVVGDVLEPRDRE +RLTHWLLTNTTNEARFRAGLPEDWSVADKTGAGEYGTCNDVGVARTPEGVPVVLAVLTRK +GEADAKPDNPLVAETAALLA--- +>[subseq from] Beta-lactamase n=1 Tax=Mixta gaviniae TaxID=665914 RepID=A0A1X1DG72_9GAMM +haALTQQLAALEKSAGGRLGVAWIDT-DGARY-GYRADERFPMTSTFKTLAVAAILHNSI +AQPGLLEKKIPIREADRVTWTPVTGHYFGKEMSIAALCAAAIEYSDNLAANYLLQELGGP +QGVTAYARSLGDTLTRLDRREPALNSAQPGDLRDTSTPAAMAANLQTLTLGKALPTAQRQ +RLISWLKQNTTGDQSIRAGVPAGWTVGDKTGAGAWGATNDLAILWPEKGAPKILAVYFIQ +SQADAANNKAVLASATRQVI--- +>[subseq from] Beta-lactamase n=2 Tax=Rhodococcus TaxID=1827 RepID=X0PTB1_9NOCA +hrSLDATIDALEAQYSTRIGVAAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE +DGSTSLDKTVVVEPGDLVENSPVTAAAVGTPMTLGQIAEAALTQSDNTAGNYLLREIGGP +QAITALARDIGDESTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD +QLLEWMRASKTSDKRMRAGLPTGWTAADKTGGGGFGTANDAGVAWSPDGAPVVLTILTDS +LTEDAQGNNQAIADTTAAVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia pseudobrasiliensis TaxID=45979 RepID=A0A370I5N8_9NOCA +---SDQRFGELERKYGARLGVFAID-SDGKRV-GYRQDERFAFDSTFKTLVCGTLLREHP +LATGYFEQVVHYTREDVVKYSPVTETRIDTGMSVAELCEAAITKSDNTAGNQLLKLVGGP +EALTKALRTLGDSVTRSDRWETELNTSIPGDERDTTTPAAIGNDYRALLTGEALGAPERD +RLKSWLVANTTGGQRIRAGVPKEWTVGDKTGTGDYGSANDVAVAWTERGTPVVISILSVK +SDQQAQADNALLADAARIVVD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces canus TaxID=58343 RepID=A0A124HI64_9ACTN +--DVTARLRALEERYDARLGVFAHHLATKRSV-RFRAGERFPMCSLFKSLAAAAVLRDLD +RDGEVLARRIHYTKDDLVIGSDQTAAHLAEGMTIAELAEVAITHSDNAAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWEPELNTAEPWRRTDTTSPYAIGRTYGRLVLGDALNRRDRE +LLTHWLLNNTTSVDRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTDDGDPIVLAVLSTM +PAPDAVRDDALVADAARAVAD-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI001020260B +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 8K308 TaxID=2530388 RepID=A0A4R4PLF5_9ACTN +---VTRGFEALEREFDARLGVYVLDTGTGREI-AYRADERFAYASTFKALAAGAVLHEYG +--LDGIDEVVTYTEDDLVDHSPVTEDFVETGMSLSELCAATLWYSDNTAGNLLFDALGGP +DGLEAILEELGDDVTEMDRYETELNEATPGDIRDTSTPRALASDLREFLLGDVLDARERE +LLRMWMVTNTTGETLIQAGLPDDWTVADKSGAGGYGGRNDIAVVWPDDGDPLVMAIMSAH +DEADAQRDDALIAEAAAVAVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-1813 TaxID=1463888 RepID=UPI0004CA2A07 +-----EALRRLEHTHRARVGAFAHNTATGATV-AYRAHTPVPLCSVFKPLAVAAVLRDLD +RNGETLARRVHYTDADLVENSPATEKHVATGMTIAELCAAAVRRSDNTAGNLLLRELGGP +TAVTAFARSLGDRTTRLDRWEPELNSAEPWRRTDTTSPAAIGRTYARLLVGDALSPSDRG +LLTAWMKTNETNTERFRAALGKDWAIADKTGSGSYGTGNDVGVAWTPDGIPIVLAVLTGK +PEQAAAYDNPLIVDVTKVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-237 TaxID=1463895 RepID=UPI00099DFCE1 +-------LRALEREYGARLGVYALDTASGRTV-VHRADELFPMCSVFKTLAAAAVLRDLD +HDGAHLAKRIHYTLQDVTDGGSITEKNIASGLTVAELCSAAIAQSDNTAGNLLLRELGGP +TAVTRFCRSLGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIGRTYARLALGDALDPGDRE +RLNRWLLSNTTSGDRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPLVLAILSTM +PEPTAPRDNTLIARTAKLLAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudovibrio stylochi TaxID=1807766 RepID=UPI00082B0C2F +--ELLDTVRKLENEIGGRIGVTLQHPKSAWSI-DYRSNERFPLSSTFKPLVCGAILARVD +RHEDSLEKIITYKKEQLVAYSPVTKENVSSGMSIGQLCEATITLSDNSAGNFLLKHIGGP +EKLTAFLRGIGDARTRLDRWETKLNEGKPKDPRDTTTPNSIARTLNKLLLTDVLKPKSRQ +QLKQWMLDDKVADALIRKHLPTGWRIADKTGAGGYGSRGIIAAIWPKAAEPYFTAIYMTG +SNADIKQRNAVIAEIGRSII--- +>[subseq from] BIC-1 class A carbapenemase n=1 Tax=Pseudomonas fluorescens TaxID=294 RepID=D2WFL1_PSEFL +----RQKIVKLEKDFGGRIGVSAIDTGANRTF-DFRADERFPLCSSFKGFLAGAVLSHSQ +QQEGLLEKRIDYKNRVMEPHSPISAQHSSTGMTVAQLAAAALQYSDNGATNLLLENLGGP +AGMTTFMRTLGDTTFRLDRWELELNSAIPGDDRDTSTPHAIARSLQKIALGEALQTAPRQ +QLVDWLIGNTTGGARIRAGVPVEWVVGDKTGTCGYGTANDYAVIWPKTSAPIVLAIYTAK +PNKEDKHSDAVIAEVTRAVLESf +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_044 TaxID=2175628 RepID=UPI000DA7E7FA +--ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTVKVFIAAAVLDASS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP +RAVERWLRGIGDRTTRVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAIVTPPGRDPVVLVVMTSR +SDPGAESSDALVAAATRTAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium stylosanthis TaxID=1803665 RepID=UPI0007C519CF +------ELETYERESGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAVIPYGQADLLDYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDATSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVTGEALSQASRV +QLTDWMVNCKTGANRLRGGLPSSWTIGDKTGNNGKDASGDIAVVWPKPDAPILIAAYTQG +GSPTAPQIEAAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Frankia canadensis TaxID=1836972 RepID=A0A2I2KKI0_9ACTN +-------LVDLERRYGARLGVFAIDTASGRSV-RHRENESFALCSTFKTYAVAAVLRAHP +LRGGDLSRTIHFSAADIVANSPVTSTRVATGMTVAELCDAAITHSDNTAGNQLLKLLGGP +AAITRFARSLGDQSTRLDRWEPDLNSATRGDPRDTTTPLAIATGYRALLLGDALPAPERA +QLKTWLIANTTGTTRLRAGLPSSWTTGDKTGAGRFATLNDVAITWPDAGGPLVMAVLSDR +PEETATAADSLLAETARAVVT-- +>[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. TaxID=1871066 RepID=A0A3S3G490_9RHIZ +-qAIEAKLAKLEGRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD +KGVEQLDRRIVFSTDALVFFSPVTETRVGGDMSVAELCMATLTQSDNTAANLLLESFGGP +AALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGNVLSRASRA +QLAGWMIMNKTGDSRLRAGMPETWMIADKTGGNGHGNNNDIAVAWTPDQGAIVVATYCEI +PTISADQRNAVVAEVGRIVAE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q3V779_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Marinobacter salarius TaxID=1420917 RepID=A0A1W6K516_9ALTE +---LLEAVKTVEQRLDARVGIALYDSGTGESW-DYHGDDRFPITSTFKTLACAALLAKVD +NGTVDLDRRVIFSKDDLVTYSPVTETRAEEEMSLRELCEATMATSDNTAANLVLGAIDGP +DGVTAYARDLGDTVTRLDRTETSLNEATPGDLRDTTSPKAMVANLRKLVLGEALSKGSRD +TLVTWLKGNRVSDNLLRAAIPPDWTIGDRSGAGGHGSRSITAVLWPPHRPPLVIAIYITQ +TDASFDERNGAIRDLGGAIVKHf +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium daqingense TaxID=993502 RepID=A0A562L1E2_9BRAD +------EFEAYERESGGRIGLHAENLASGAKL-AWRADERFVMCSTFKASLAACVLARAD +RGEEQLAAMIPYREADLLEYAPVARQNLAAGMSVSEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSRPGDPRDTTTPAAMAGNLRRLVLGAALSPASRA +QLTDWMVNCKTGANRLRGGLPASWKIGDKTGYNGKDAAGDIAVVWPKPDTPILITTYVQG +GTPSAAQIAAVFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Plasticicumulans acidivorans TaxID=886464 RepID=A0A317MVF0_9GAMM +------RLAVLEGTLEARLGVAVLDTHSGELR-GRRLDERFPLCSTFKLIACGALLARVE +AAALDLVQPVAIRAEDIVSHSPLTGPRVGGTMRFAELCAAALTQSDNTAGNLILRAIGGP +AGLTAYVRALGDTQTRLDRWETALNAATPGDVRDTTTPAAMARLLHTLLLGERLAPAART +RLIEWLLANRTGDAKLRAGLPPGWRIGDKTGGGEYGTSNDVAIIWPGQGPALIVCVYLTQ +STASFAARDHAIAEVARMLA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium japonicum TaxID=375 RepID=A0A4Y3Z210_BRAJP +------ELESYERETGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARAD +RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVVGEALSPASRT +QLTEWMVGCKTGANRLRAGLPAGWKIGDKTGNNGKDASGDIAVAWPKNKVPILIAAYTQG +GTPNAAQIEAAFARVGRMVAE-- +>[subseq from] Beta-lactamase n=2 Tax=Actinocrispum wychmicini TaxID=1213861 RepID=A0A4R2JKB4_9PSEU +------DFGRLERDFDARLGVYAVDTANGREV-AFRADERFAYASTHKVFTAGAVLQRIP +--IGDLERTVKYSQNDLVANSPVSEKQVATGMTLRAAMDAAIRYSDNTADNLLFRELGGP +NGLAAAVRATGDTTTHVDRIEPALNDTAPGDIRDTSTPRAMTATMRAFTLGNALPEDKRT +ILVDLMRANQTGGTVIRAGVPAGWQVGDKTGTGGYGTRNDIALVWPPQRAPILLAILSDK +KAKDAKTDDKLIAQAAAAALAAf +>[subseq from] Beta-lactamase n=1 Tax=Nocardia neocaledoniensis TaxID=236511 RepID=A0A317NUX6_9NOCA +------SFADLESKYGARLGLMVIDTGSGRTV-GYREGELFPMASTFKGLACGVLLQAHP +LDTGYFDQVVHYTAADIVANSPETEKHVDSGMTVAALCDAAITQSDNTAGNMLLRLLGGP +AGFTDSLRRLGDPVSRLDRWETELNTAIPGDVRDTTTAAALAADYRALVLGDALREPERA +RLATWLKASRTGAKRIKAGLPADWTVGDKTGTPAYGSALDVAIAWPPNRAPLVLAVLTTK +PDQNAEPSNELVAEATKAALA-- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_050 TaxID=2175664 RepID=UPI000D92FB59 +--AAERAFAALETEHDARLGVVAIDTGSGVGV-AHRADERFAFASAAKVFIAATVLDAAA +--PDDLDAVVPIGQGDVLSYAPVTGQHVGSGMTVRALLAAMVRSSDNTAANLLVARVGGP +AAVQRWLRGIGDDVTRVDRVEPDLNEAVPGDERDTTTPAQFAADLRTVLLGGALDPDDRA +LLVDLMRGTTTGAGTIRAGVPEGWTVADKTGTGSYGVRNDVGIVTPPGRDPIVLVVMTRH +DTTDAEPDDALVAAATRAA---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A3KEZ0_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Geodermatophilus nigrescens TaxID=1070870 RepID=A0A1M5JPJ4_9ACTN +---VAGDLAALEARFDARLGVFAVDTGSGATL-EHRADERFAYASTIKALAAGALLARTS +--PADLQRPVPVTPADLTTYSPVTETRVGGSMTLAELCDAAVRSSDNTALNLLLRELGGP +AGLDAALEAIGDDVTEVARTEPELNSAVPGDPRDTTTPRALAGSLRAYAVGPRIAEEDRA +HLLDWLRRNTTGDALVRAGVPADWDVGDKTGTGAYGTRNDVAVLTPPGRAPIVLAVMSSR +DEPDAGHDDALIAEAARVVV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A3KEX5_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces formicae TaxID=1616117 RepID=A0A291QN41_9ACTN +-----ARLKALERKHDARLGVYALATGTGATL-AHRADERFAFCSTFKTLAAAAVLARNP +--LSHLDRRVTFTRAQVNSISPVTEDHIATGMTIKQLCDAAVRHSDGTAGNLLMRDLGGP +ARLTDYLRDLGDTVSRMDQYEPELNRARPKDPRDTTTPRAVAADYQKLVLGDALPAAKRT +LLKDWLERGVTGDKRIRAGLPKGWTVAEKTGTGVYGRANDIGIAWPGTGAPLVIAVMSDR +SGYDARPKDAMIAEATAEIV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces canus TaxID=58343 RepID=UPI000371978D +--DVTARLRALEKRYDARLGVFAHHVTTGRSV-RHRADELFPMCSVFKALAAAAVLRDLD +RDGEVLARRIHYTEADLVIGSDRTAAHLAEGMTIAELADVAITYSDNTAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWEPELNTAEPWRRTDTTSPYAIGRTYGRLVLGDALNRRDRR +LLTHWLLNNTTSVNRFHAGLPKSWTIADKTGSGSYGTANDVGVTWTDAGDPIVLSVLSTM +PAQDAVRDDALVADAAAVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia xishanensis TaxID=238964 RepID=UPI00082DB233 +----HERLVELERQFDARLGVYALATGTGVTI-AHRADERFAFCSTFKGLAAAAVLHRNP +--LSHLDTVVSYTEADLLKSASITSRHVATGMTIRDLCDAAVRFSDGTAGNLLLRDLGGP +AELTAYVRSLGDTVTRMDRIEPAITEATPGDPRDTTSPRALGTDYQRLVLGDALPADKRA +FLRDLLERNATGAQRIRAGVPQDWTVADKTGTGDYGTLNDIGIVWPPASAPLVIALMSSK +TTVDAPYDQALLAEAAAYVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00128F4570 +---------------------------------SFRPEERFPMMRTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00035CFF1E +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPVTEQHLAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARCETALNEATPGDRRDTSTARALAEDLREYAVDDALEPADRD +ILNAWLRGNTTGGALIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDDALIAQATEVVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=A0A542XUY9_9ACTN +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPVTEQHLAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARCETALNEATPGDRRDTSTARALAEDLREYAVDDALEPADRD +ILNAWLRGNTTGGALIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDDALIAQATEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TAA204 TaxID=1289387 RepID=UPI000684DD29 +-dKLHPQLAALERKFDARLGVYALGTGTGETV-VHRADERFAFCSTFKGLAAAAVLHRNP +--LSHLDTVVTYDEDDLMKHSPVTGRHVASGMTIRELCDAAVRHSDGTAGNLLLRDLGGP +GRLTAYARSLGDKVTRMDRTEPAITEAAPGDPRDTTSPRAFGTDYRKIVLGDALPSGKRG +FLRDLLERNTTGARRIRAGVPASWKVADKTGTGDHGTLNDIAVAWPPRSPPLVIAIMSSR +DSKDAPYDEDLIAEAAAYV---- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus wratislaviensis TaxID=44752 RepID=A0A3D9QYL8_9NOCA +hrSLDATIDALEAQYSTRIGVAAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE +DGSTSLDKTVVVEPGDLVENSPVTAAAVGTPMTLGQIAEAALTQSDNTAGNYLLREIGGP +QAITALARDIGDESTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD +QLLEWMRASKTSDKRMRAGLPTGWTAADKTGGGGFGTANDAGVAWSPDGAPVVLTILTDS +LTEDAQGNNQAIADTTAAVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia neocaledoniensis TaxID=236511 RepID=UPI000D70F8BD +------SFADLESKYGARLGLMVIDTGSGRTV-GYREGELFPMASTFKGLACGVLLQAHP +LDTGYFDQVVHYTAADIVANSPETEKHVDSGMTVAALCDAAITQSDNTAGNMLLRLLGGP +AGFTDSLRRLGDPVSRLDRWETELNTAIPGDVRDTTTAAALAADYRALVLGDALREPERA +RLATWLKASRTGAKRIKAGLPADWTVGDKTGTPAYGSALDVAIAWPPNRAPLVLAVLTTK +PDQNAEPSNELVAEATKAALA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB58_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces canus TaxID=58343 RepID=UPI0009A0A89B +--DVTARLRALEERYDARLGVFAHHLATKRSV-RFRAGERFPMCSLFKSLAAAAVLRDLD +RDGEVLARRIHYTKDDLVIGSDQTAAHLAEGMTIAELAEVAITHSDNAAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWEPELNTAEPWRRTDTTSPYAIGRTYGRLVLGDALNRRDRE +LLTHWLLNNTTSVDRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTDDGDPIVLAVLSTM +PAPDAVRDDALVADAARAVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Simplicispira lacusdiani TaxID=2213010 RepID=UPI000E7152DC +--QWAETLAGIERTVQGRLGVAMLDTGTGLAL-GWRQDERFAMASTFKLALAGWMLALVD +QGRERLDARVFYGREALVAYSPATASRADEGLTVGELCAATVSLSDNTAANLLLARHGGP +AAFTAFVRSLGDGVTRLDRNEPTLNEAAVGDPRDTTTPQAMLQTMRKLVLGDALTPASRT +WLQRWLVETSTGDKRLRAGVP-GWRVGDKTGTASSGTANDIGVLWPPGGAPVLVVCYLTR +STAAPGQRDAAIADVARAVVA-- +>[subseq from] Beta-lactamase n=8 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB53_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces fradiae TaxID=1906 RepID=BLAC_STRFR +--RVEGRLRALERTHDARLGAFAYDTGTGRTV-AYRADERFPIASMFKTIAVAAVLRDLD +RDGEVLARRVHYTADYVKRYSPVTGENVANGMTVAELCEATLTRSDNTAANLLLRDLGGP +TAVTRFCRSVGDHVTRLDRWEPELNSAEPGRVTDTTSPRAIGRTYGRLILGDLLAAHDRE +RLTRWMLDNRTSDERFRKGLPADWLLADKTGGGDYGTNNDAGVAWPPGRPPVVLAVQTTR +FTPDAEADNVLVAEAARLLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium rifense TaxID=515499 RepID=A0A5D3K3U5_9BRAD +------ELESYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEKLAAMISYGKTDLLEYAPVAKQNLSAGMSVADMCKASVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPVAMAGNLKRLVTGEALSPASRA +QLTDWMVGCKTGANRLRGGLPAAWKIGDKTGNNGKDASGDIAIAWAKPDAPILIAAYTQG +GTPNPTQIEAVFARIGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinoalloteichus hoggarensis TaxID=1470176 RepID=UPI000B8ABD97 +-----AEFAELEDRFGVRLGVYAYDTGNATVV-AHRPDERFPMCSTFKALLGAAILHETS +--TVELDRHFTWSADDLLHHSPITEQHVASGLSAEQLCDAAVRYSDNTAANLLLNEIGGP +AGFTSFVRAIGDETTRLDRVEPDLSTGEPGDERDTTTPRAFADTLRSLVLGDALAPERQE +ILTEWLLTNVTGANRIRAGTPAGWRVGNKTGSGGYGTVNDTAVLWPPDRAPILLTVYTTI +GVRYAEYDEAVIAEAASIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Actinoalloteichus hoggarensis TaxID=1470176 RepID=A0A221W5L2_9PSEU +-----AEFAELEDRFGVRLGVYAYDTGNATVV-AHRPDERFPMCSTFKALLGAAILHETS +--TVELDRHFTWSADDLLHHSPITEQHVASGLSAEQLCDAAVRYSDNTAANLLLNEIGGP +AGFTSFVRAIGDETTRLDRVEPDLSTGEPGDERDTTTPRAFADTLRSLVLGDALAPERQE +ILTEWLLTNVTGANRIRAGTPAGWRVGNKTGSGGYGTVNDTAVLWPPDRAPILLTVYTTI +GVRYAEYDEAVIAEAASIAL--- +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBL7_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAINYEQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI001320C001 +---ALDSIRSLEMSRGGRLGVAVLDTGSGRRL-QYRADESFAMCSTHKFLSAVAVLSLVD +QGKLALEKPVKYGKADLLDYAPVAREHVERGMTVDELCAAATVWSDNTAANLLIELLGGP +AGWTRFARSIGDDASRLDRTEPALNSAIPGDPRDTTTPDAMLANLQQTLLGTVLSDSSRG +RLQNWMLSGTITDTLLRAGVPLTWRVGDKSGAGRNGTRNDIGIIFPPHASPILAAIYYTE +STGSLASREEVIAEVGGIIAETf +>[subseq from] class A beta-lactamase n=1 Tax=Terriglobus sp. TAA 43 TaxID=278961 RepID=UPI000645EEB5 +-qRLPQQVATLEKDNGGRIGVYALDTGNGKSA-GIREDERFPMCSTFKFLLAAAVLKLVD +DGKQSLDQPLPIPNKPLIGHSPLTEPHAGATMPIAALCNAILNQSDNTAANVLLEAIGGP +PAITAFAHTIGDESTRLDRNEPDLNTSIDGDPRDTTTPVAMAKNLQRVLFGNALKPASRR +QITEWMENSLTGLERLRKDMPEGWRAADKTGSNGEHTTNDIAVLWPMRRPPVIVTCYITQ +CPGPETKRGAMIAEIGRFVR--- +>[subseq from] Beta-lactamase (Fragment) n=6 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBT2_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium loti TaxID=381 RepID=A0A2N5AXH8_RHILI +--EAENKLAELERKHPGRFCVTILDLGSGKRI-QHRADERILMCSTFKALLAALVLARID +KGEAKPDERIAFTSKDLVAHSPVTKPHADGPLTIAELCDATVTISDNSAANLLLARFGGP +AALTAFCRRLGDDVTRLDRIEPELNHDGPDDQRDTTTAAAMAETLRKLLFTDVLSAASRS +QLAAWLITNKTGDKRLRAGLPGDWLVGDKTGTNGHGNANDIAVIWPQDRAPLIVTVYCEI +PKISSKERDAVIAEIGRIAS--- +>[subseq from] Beta-lactamase n=10 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A1V3D7E1_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Lysobacter sp. Root690 TaxID=1736588 RepID=A0A0Q8JHM3_9GAMM +---WQTRLRDLEKHSGGRLGVAVLDTGNGQRM-AWRENERFRMCSTFKYLLAAAILRQVE +LGKVTLSQQVPITAADMIAHAPFTQPLVGRSASVAQLCEATVTLSDNPAANLLYPLVGGP +QGLTRFLREIGDGVTRTDRTEPTLNGGAPDDPRDTSTPTAQIATMQRLLLSDALKESSRK +QLIAWLVANKTGDKRLRAGLPAGIRVGDKTGSGDD-ATNDVAIVWPPGRAPILIVSYLAT +AKLDGAGRDAVLASVARIVSEQw +>[subseq from] BKC/GPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Shinella zoogloeoides TaxID=352475 RepID=UPI000E65AAC0 +--KLKKRLAELEGRHKGRIGVAIHNLATGAQL-GHRADERFLMCSTFKSLLAGHILARVD +RKEEDLDRRIVVKKSDLVDWSPVVEKRVGGDISIAELCAATITLSDNAAANLLLAASGGP +KAVTQFLRGFGDEVTRLDRTEPKLNYDAPDDERDTTTPLAMTETLRRLVVSDVLSPSSKA +QLAAWLVMNKTGDTRLRAGFPADWMTGDKTGTNGQGNANDVAVAWSPDRGAIVVTAFCEI +PGISGDERNAVIAEIGRIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces niveus TaxID=193462 RepID=A0A1U9R0C0_STRNV +---TKGAFARLEREFDARLGVYAIDTGNSRSI-THRPDERFAYASTCKALLAAVMLDKYS +--LRQLDRLVRYDRNDLAGYSPITEKHLATGLTLRELCDATVRYSDNGAANLLFRELGGP +KSLQSALASIGDRVTRCDRYEAELSDAVPGDLRDTSTPRALATDLRAYVVDDALAPDKRA +VLTDWLKRNTTGDKVIRAGAPDGWQVGDKTGTGGYGTRNDIAVVWPPKAAPIAIAVLSRR +DFKDAEPDDALIAEAARITLN-- +>[subseq from] Beta-lactamase CARB-6 n=2 Tax=unclassified Vibrio TaxID=2614977 RepID=A0A6B8N5H7_9VIBR +-dSLTKQIALIEQQSGGRLGVAVLDTQNHKQW-QYHGDDRFPMMSTFKTLMCANALYLAE +QKKLNLNATTKVKKSVLVTWSPITEKLIGQEITVQKACEATMLMSDNTAANIVLHQIGGP +EQVTQFVRSLDDKVTRLDRFEPELNQATPGDKRDTTSPSAMVELLNTLLLQDGLNQESQQ +QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPVILSIYLTQ +TQLDMAQRNRVINRVANLVFEQf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces rubrolavendulae TaxID=285473 RepID=A0A1D8G8V8_9ACTN +--RVEGRLRALERTHNARLGAFAYDTGTGRTV-AYRADERFPIASMFKTIAVAAVLRDLD +RDGEVLARRVHYTADYVKRYSPVTGENVANGMTVAELCEATLTRSDNTAANLLLRDLGGP +TAVTRFCRSVGDHVTRLDRWEPELNSAEPGRVTDTTSPRAIGRTYGRLILGDLLAAHDRE +RLTRWMLDNRTSDERFRKGLPADWLLADKTGGGDYGTNNDAGVAWPPGRPPVVLAVQTTR +FTPDAEADNVLVAEAARLLAE-- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderiales TaxID=80840 RepID=A0A1E3Z895_9BORD +--AALDELARLERLADGRLGVCIVDTASGEEL-GRRADERFQMLSTFKLLAAGFVLARHD +RGEDSLDRRIRYTRQDLVNWSPVTGKHVGDRMTLAELCHATVTTSDNTAANLILRSFGGP +EALTRFIRSLGDGVTRCDRYEPELNVPHATGMLDTTTPHAITRTLGRLTVGETLSPASRE +RLQAWLVGNTTGDKRLRAGIPAGWRIGEKTGTYSKVGANDIGLAWPPGRPAILMSVYVAS +TRVSDEVKDQVIAKVAQLVG--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus timonensis TaxID=1033734 RepID=UPI000A04C615 +--NTDEKIAQLENEFDARIGVYAIDTGTNTTI-EYRPDERFAYASTYKALAAAILLQQNT +--MEELKEVITYTKDDLVTYSPITENYVDTGMTLLEVGEAAVRFSDNTAGNILFEAIGGP +EGFEQALRQIGDTVTQADRVEPDLNFFKPGDTRDTSTPKALANSLQAFTVGESLSEDKRK +LFMEWLKDNATGDTLIRAGAPEGWIVGDKSGAGVYGTRNDLAIVWPPNREPIILAILSNH +TTEDATYDDALIARTAEVVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=UPI0002DA1818 +---ALDSIRSLEMSRGGRLGVAVLDTGSGRRL-QYRADESFAMCSTHKFLSAVAVLSLVD +QGKLALEKPVKYGKADLLDYAPVAREHVERGMTVDELCAAATVWSDNTAANLLIELLGGP +AGWTRFARSIGDDASRLDRTEPALNSAIPGDPRDTTTPDAMLANLQQTLLGTVLSDSSRG +RLQNWMLSGTITDTLLRAGVPLTWRVGDKSGAGRNGTRNDIGIIFPPHASPILAAIYYTE +STGSLASREEVIAEVGGIIAKTf +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus opacus (strain B4) TaxID=632772 RepID=C1AR67_RHOOB +heSLDAKIEALEAQYATRIGVTAVDPQTGAVY-SHRGDERFAMCSTFKAYASAAVLRKIE +DGSTSLDKTVMIEPADLVENSPVTAAAVGTPMTLGQIAEAALTQSDNTAGNYLLREIGGP +QAITALARDVGDASTRLDRWETELNTAFRGDPRDTTTPTGLAHGFRALLLGDALDAASRG +QLLDWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWSPDGSPIVLAVLTDS +LTEDAQGNSQAIADTTTAVI--- +>[subseq from] Beta-lactamase n=1 Tax=Erwinia persicina TaxID=55211 RepID=Q8L1Z4_9GAMM +--SLQRQLAALETEVNGRIGLSLIDSASQQAW-SYRGDERFPLCSTFKLLLVAAVLKRSE +SQPALMQQTLHWTPADHLSYMPVTAKHPQ-GMTVSDLCAAALQYSDNLAANVLLTLLGGP +ASVTRLARSLGDSVTQLDRNEPTLNTAIPGDPRDTTTPLHMSHSVQQLLVKSGLQTAQQQ +QLIAWLKGNTTGKNAIAAALPAGWEIGDKTGSGGYGTTNDVAILWPPGKAPLILAIYFTQ +HAPEAKSRQDVLAKAAAIALK-- +>[subseq from] class A beta-lactamase n=1 Tax=Thiomonas intermedia TaxID=926 RepID=UPI0009A54FFC +--ALSRAVSHAEASLHARIGIAMIDTGDGATW-SHNGDERFPMNSTYKAFACAAVLSRVD +ANTLNLDMMVPIDRARLVTYSPVTEKVQPGGLSLSDLCSAAVSVSDNTAGNLVLDAIGGP +SGFTEFMRSIGDRATHLDRLEPELNEATPKDVRDTTTPHAAATDLRKLLLGHVLSAPSKR +QLSQWMVGNKVTQGLLRAGFPSDWRVADKSGAGGHGSRSIIAIAWPPERAPIVVAIYITQ +TVAPMSRCDQTIAQLGEAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas campaniensis TaxID=213554 RepID=A0A060BEZ6_9GAMM +--NLLTEVERIERQLDARVGFAAYDLETEQRW-EYNADQLFAMSSTFKTLACASLLQRVD +EGSEQLGRRVKVSASDIVTYSPVTEAYADNRISLFELCEATMTTSDNTAANLILQAIGGP +QAVTAFVRDLGDSVTRLDRWETELNEAAPHDERDTTTPNAMVSNLEKLVVGNALSPQSKN +QLREWLVNNEVADGLFRSQMPDEWVIGDRTGAGGFGSRSITAVIWPPEREPTIVAFYITE +TDASFEERNTAIAELGSVIR--- +>[subseq from] class A beta-lactamase n=1 Tax=Roseomonas sp. 18066 TaxID=2681412 RepID=UPI00135AC608 +---LEKRLAEIEARSGGRLGVAIKVGGSSRQA-GHRLDEPFPLCSTFKLLAAAAVLARVD +AGQEQLDRPIRFTRDQLVAYSPGTEAGAGGPLPMRHLCEVAVTLSDNTAANLMLESLGGP +AGLTAWLRRLGDSVTRLDRIEPALNEGTPGDPRDTTTPLAMSQTMEKLLLGTALKPDSRA +LLTRWLVENKTGDERLKAHLPQGWRAGEKTGTGPRGSTNDAGILWPADGAPLLVSAYLTG +TPAPLAARNAALAEVGKAVAAFy +>[subseq from] Beta-lactamase n=1 Tax=Halomonas alkaliphila TaxID=272774 RepID=A0A386X3D1_9GAMM +--NLLTEVERIERQLDARVGFAAYDLETEQRW-EYNADQLFAMSSTFKTLACASLLQRVD +EGSEQLGRRVKVSASDIVTYSPVTEAYADNRISLFELCEATMTTSDNTAANLILQAIGGP +QAVTAFVRDLGDSVTRLDRWETELNEAAPHDERDTTTPNAMVSNLEKLVVGNALSPQSKN +QLREWLVNNEVADGLFRSQMPDEWVIGDRTGAGGFGSRSITAVIWPPEREPTIVAFYITE +TDASFEERNTAIAELGSVIR--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces canus TaxID=58343 RepID=A0A101SFL6_9ACTN +--DVTARLRALEERYDARLGVFAHHLATKRSV-RFRAGERFPMCSLFKSLAAAAVLRDLD +RDGEVLARRIHYTEDDLVIGSDQTAAHLAEGMTIAELAEVAITHSDNAAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWEPELNTAEPWRRTDTTSPYAIGRTYGRLVLGDALNRRDRE +LLTHWLLNNTTSVDRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTDDGDPIVLAVLSTM +PAQDAVRDDALVADAARAVAD-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Acidovorax TaxID=2684926 RepID=A0A1E3ZSK1_9BURK +--AWNEDLASIERTAQGRLGVAMLDTGSGLAL-GWRRDERFAMASTFKLVLAGWMLALVD +QGKERLDARVRYAAADVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGS +AGFTAFVRSLGDEVTRLDRTEPTLNEAAVGDPRDTTTPLAMLQTLQKLVLGNALSPTSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPQGGAPVLVTCYLTR +SMASPEQRDAAIAQVARAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. Root267 TaxID=1736505 RepID=UPI00070C85DA +--QWNDTLAGIEHFAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD +QGKERLDARVHYAAADVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANLLLARHGGP +AGFTAFVRSLGDGTTRLDRTEPTLNEAKVGDPRDTTTPLAMLQTLQKLVLGDVLTAPSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVLWPPGGAPVLVTCYLTR +STAKPEQRDAAIAQVARAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. RP5T TaxID=2490848 RepID=A0A3R8SQ78_9ACTN +--DVTARLRALEERYDARLGVFAHRPSTGRSV-RYRADERFPMCSVFKALAAAAVLRDLD +RHGEVLARRIHYTEDDLVMGSDQTKAHLAEGMTIAELADVAITYSDNTAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWEPELNSAEPWRLTDTTSPYAIGRTYGRLVLGDALNRRDRE +LFTHWLLHNTTSVNRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTEAGDPIVLSVLSTM +PAPDAVRDDALVADAASVVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces fradiae ATCC 10745 = DSM 40063 TaxID=1319510 RepID=A0A1Y2NVH3_STRFR +--RVEGRLRALERTHDARLGAFAYDTGTGRTV-AYRADERFPIASMFKTIAVAAVLRDLD +RDGEVLARRVHYTADYVKRYSPVTGENVANGMTVAELCEATLTRSDNTAANLLLRDLGGP +TAVTRFCRSVGDHVTRLDRWEPELNSAEPGRVTDTTSPRAIGRTYGRLILGDLLAAHDRE +RLTRWMLDNRTSDERFRKGLPADWLLADKTGGGDYGTNNDAGVAWPPGRPPVVLAVQTTR +FTPDAEADNVLVAEAARLLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. Huas11 TaxID=2183912 RepID=A0A495L849_9ACTN +----DTEFTRLEQEFDARLGVYALDTGTDQAV-EFQADERFAYCSTFKVLAFGAVLDRTP +--VEELDRVVTFSEADLVFHSPITQEHVSSGMTLHEAGDAALRHSDNTASNLLLKELGGP +EALDAALEEIGDDVTSVDRTAPEMAEAVPGDGRDTSTPRAMATSLREFALGDVLSEDERD +ILVGMMRANTTGEELIRAGVPEGWEVGDKTGACGYGTRHDIGVAWPPEGDPIVLAVMSGR +DEAGAGYDDALVAQATRVAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A246HM25_STEMA +----AKDFAALEAASGGRLGVTLLNTGTGWRT-GNRQDERFPMCSTFKFVLSAAVLHLAD +QGRLLLDQRVPVRQQDMLSHAPVTTRHIGKDMTVRDLCRATMITSDNPAANLLLGRVGGP +AGVTAFLRANGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRFVLGDVLKPASKQ +QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ATVDDAGRNDVLRQVAVI----- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia fluminea TaxID=134984 RepID=A0A2N3VF75_9NOCA +----TATFADLEAKYGARLGLSVVDTGTAATA-NYREGERFPMASTFKGLACGALLQAHP +LSTGYFDQVIRYTAADIVVNSPETEKHIDTGMTVTALCDAAITLSDNTAGNMLLRLLGGP +AGFTAFLRTLGDTVSRLDRWEPELNTAIPGDERDTTTAAALTANYRALVFGTALQEPERA +QLATWLKASKTGAERIKAGLPTDWIVGDKTGTPAYGSALDVAVAWPPNRAPLVLAVLTTK +PDQNADPSNDLVAEATKAAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas sp. CFBP 7698 TaxID=2082399 RepID=A0A3A5EPF1_9XANT +--MLRAQWADIERGTGGRLDISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLRRVD +EGKLTLAQPVKIRASDMLEHAPVTKRHVGGTLSVGELCRATMIHSDNPAGNLLFPLVGDP +AGLTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK +QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG +AKVDAAARDAALKAVAVAVREW- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces kanamyceticus TaxID=1967 RepID=UPI0006E34FA6 +-----TRLKALERKHDARLGVYALATGTGATL-AHRADERFAFCSTFKTLAAAAVLDRNP +--LSHRDTRITYTRAQVNSISPVTEDHIATGMTVKQLCDAAVRHSDGTAGNLLMRDLGGP +DRLTDYLRDLGDTVSRMDQYEPELNRARPGDPRDTTTPRAIATSYQKLVLGDALPAAKRT +LLKDWLERGVTGDKRIRAGLPKGWTVAEKTGTGFYGRANDIGIAWPGTGAPLVLAIMSDR +SGYDARPKDALIAEATAEIV--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. BMG51109 TaxID=1056816 RepID=UPI0004673903 +-----RAFADLETQHTARLGVYAVDTGTGRTA-VHRDGERFPVASTFKGLACGVLLRDHP +LSTGYFDQVIRYPATDLVDASPVTQKRVDTGMTVAELCHAAITASDNTAGNQLLKLLGGP +AGFTASLRSLGDTVTRLDRWETELNTAIPGDERDTTTPAALAADYRLLVLGDVLGESERA +QLKSWLVDNTTGGARIRAGLPAGWIVGDKTGSPAYGGALDVAIAWPPDRAPLVIAVLSGK +SEPTAAADNPLVAEATRAAVR-- +>[subseq from] Beta-lactamase n=2 Tax=Acidovorax delafieldii TaxID=47920 RepID=A0A561XQU8_ACIDE +--AWNDALASIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD +QGKERLEARVHYPATDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDEVTRLDRTEPTLNEAAVGDPRDTTTPLAMLQTMQKLVLGNALSSMSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTAGSGTANDIGVLWPAGGAPVLVTCYLTR +SKASPEQRDAAIAQVARAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces bungoensis TaxID=285568 RepID=A0A117R9V7_9ACTN +--EIVRRLKGLEQRHAARLGVHARDTATGRTV-RYRADERFPICSVFKTPAVAAVLRDLD +RDGEFLARRVRYTERDVRDYAPITGRNLAAGMAVEDLCAAAIRHSDNAAANLLLRELGGP +AAITRFCRSIGDRTTRLDRWEPDLNSAEPWRATDTTSPCAIGRTYARLVLGTALAPGDRE +RLTGWLLGNTTGGERLRAGLPGDWTVADKTGTGSYGTGHDVGVTWPPGRAPLVLAVLTTR +HEPDASPDSRLIAETAALL---- +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis tolypomycina TaxID=208445 RepID=A0A1H4UTV2_9PSEU +------DFAPLERSFDARLGVYALDTGSGREI-AHRADERFGYASAHKALSAAAVLQRTS +--LDGLAKHLTYTRADLRANSPVTEKRVATGISLRDAIDAALRYSDNTAANLLFRELGGP +PGLAAALRGIGDTTTHVDRIEPELNDLAPGDVRDTSTPRAMAGTLRTFALGDALPPEKRT +VYTDMMRANQTGATVIRAGTPAGWAVADKTGTGEYAMRNDIAVVWPPGRAPIVLAVMSSR +QAEDAEHDDRLIAQAAKLVFDAf +>[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus eapokensis TaxID=1873482 RepID=A0A1Q5TSU0_9GAMM +---IIHQLSILEKNANGRLGVVLLDTTDHSII-SYRENERFPLCSTSKLMTVSAMLKKSE +TNVHLLNQRVHYQQSELVEYSPMTEKHLKDGMTLGELSAATLQYSDNTAMNLLLNQLHGP +NEVTRFARIIGDNSFRLDRYEPELNTAIPGDERDTSTPQAMAKSLYYLVLGDALATTQRE +QLVKWIKGNTTGGASIRAGVPKDWIVGDKTGRCDYGTTNDIAVIWPPNRAPLVLVTYFTQ +PDSKATARPDVLAAAARIVTQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0005173611 +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAAVPDGWVVGDKTGSAGYGTRNDIAVIWPPDHAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0N9HJA8_9BACT +------SIAEIEARVGGRVGVFALDTGSGKVL-AHRPDERFAMCSTFKWVLAATVLAQVE +RNLLSLGDHVLYGQADLLAYAPVTSKHAAKGMTVSDLTRAAIVVSDNTAANLLLSKLGGP +SVVTEFARSCGDAITRLDRNEPTLNDNESGDLRDTTSPRAMATLMNKVLCGNRLSSTSRD +LLLQWLRDCDTGHDRLRAKLPKDWLVGDKTGTGEHGAVNDVAIAIPPGRSPILIAAFLSE +GKADRSALVAAHASISRLVADHf +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0005B620D1 +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAAVPDGWVVGDKTGSAGYGTRNDIAVIWPPDHAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C9FBC92 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVI---- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000BACEBBF +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces caatingaensis TaxID=1678637 RepID=A0A0K9XIQ2_9ACTN +-----APFRQLEQRFGARVGLYALDTGTGREV-TYRADERFAHCSTFKALAAGALLHHAS +--DAELDQVVTYRPEDLQKWAPIARKHVATGMKLREVAAAAAEYSDNTAANLLLDHLGGP +AGLQKELRGIGDSTISTDRTEPGLSDAVPGDTRDTSTPRSIATDLRRYVLGSVLSDGRRQ +LLTDWLVHNTTGDRYIRAGVPAGWKVGDRTGNGGYGTRNDIAVAWPPGRSPVVIAVLSDR +GEAGARSDDALIAEVTKAAVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces pratensis (strain ATCC 33331 / IAF-45CD) TaxID=591167 RepID=E8W3G7_STRFA +------AFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGMHT +--LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP +RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEKRA +VLTDWLRRNTTGDALIRAGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR +ASRGAKPQDALIARAARVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. RKND-216 TaxID=2562581 RepID=A0A4S2R6B1_9ACTN +--RLVRRLTELENRHAARLGVFAHDTATGRSV-RYRAQERFPMCSVFKTLAVAAVLRDLD +RHGEFLARHVRYDEKTVTDYAPVTGKNLAHGMTVQELCDAAIRYSDNAAANLLLRALGGP +RAVTRFCRSVGDRVTRLDRWEPELNSAEPWRRTDTTTPRAVAGTYARLTLGDALDRADRR +RLTGWLLGNTTSGAKFRAGLPDGWVVADKTGGGEYGTNNDVGLTWPPGRPPIVLAVLTTR +FTPDAERIDPLVAETASLVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis baichengensis TaxID=280240 RepID=UPI00034671FB +-----AGFERLEEEFGARLGVYALDTGSGEEV-AYNADERFAYASTFKVPACGAVMEEHS +-LKEMEETVVHFDEEDLVTYSPITEDHVDTGMTLMEVCDAALRYSDNTAANLLLEEIGGP +EGFQEAMRELGDEVTVSARWETELNENKPGDERDTSSPRAFAGNLEEYVLGDTLEEDKSE +ALADMMVRSTTGDTLIRAGVPEDWKVGDKSGMPGYGARNDIAVMWPPEGDPIVLAAYSTK +DTEDAESEDELIAQAAEEAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Kosakonia cowanii TaxID=208223 RepID=UPI00111F8AAC +-------IARLEEKLHARIGIAVIDTASGKSV-SYRGDERFPLNSTHKALLCGALLSKVD +QGEFALSDTTQFSKETLVDYSPVTSKFVAPKMSWQQVCSAAISYSDNTAANLAAQKLGGP +QKVTAFFAGLGDNVTRLDRKEPELNSAVPGDLQDTTTPLAVSRTLEKLTLGDALKPESRA +QLVQWMKDDKVADALLRASLPSGWKIGDKTGAGAYGSRSIISVVWPKKGQPIIVSVYITQ +TEATLAQSNDAIARIGKSIFE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. PsTaAH-124 TaxID=1157638 RepID=UPI0003619AD3 +--RATDALRALEERYSARLGVHARNTRTGQSV-GYRAGERFALCSTFKVFAAGAVLRDHA +-GSAPLDKVVRYPDRDILLNSPVTQQHVGSGMTVGELCAAAIRHSDNCAGNLLLRELGGP +AGLTAFFRSLGDRVSRLDRWEPDLNSAGPGELRDSTTPQALGASLERLTVGDELSGAARE +QLLTWLKGNTTSAARFRAGLPRGWVVGDKTGTGDYASANDIGVAWTTRGTPLVLVVLTSK +DAPDATVDEALIADAAAVLAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. T7 TaxID=627444 RepID=UPI00135C1BC6 +-qSLDAKIEALEAQYATRIGVTAVDPATGAVY-SHRGDERFAMCSTFKAYASAAVLRKIE +DGSTSLDKTVVIEPGDLVENSPVTAAAVGTPMTLGQIAEAALTRSDNTAGNYLLREIGGP +QAITALARDLGDESTRLDRWETELNTAFRGDPRDTTTPTGLAQGFRALLLDDALDAASRD +QLLDWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWSPDGSPVVLAVLTDS +LTEGAQGNNQAIADTTAAVIE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces spectabilis TaxID=68270 RepID=A0A5P2X6C3_STRST +--AYARAFRKLEHKFDARLGVYAVDTGTGREV-AYNDSRRFAYNSTFKALAAAEVLRQYA +--PDRLDQVVKYSKDDLIANSPVTEKHVDTGMTLRALCDAAVRYSDNTAANLMFDKLGGP +KGLDAALERIGDDVTRMDRVEPFLSRWVPGEKRDTSTPRALAKDLRAYVLGDVLAAPERA +QLATWLKTNTTGDHVIKAGVPKNWVVGDKTGTGSYGARNDIAVVWRPGAAPLVVAILSHR +GDRDAAPDDKLIAEAASVVA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillaceae bacterium TKL69 TaxID=2594883 RepID=A0A516KC56_9BACI +-----KDFAKLEKTYDARLGVFALHTGTNEMI-AYRADERFAYASTHKALAVGALLQQKS +--IPELNKRIRYSKNDLVNYNPITEKFVELGMTLKELCEASIRYSDNTAGNLILNELGGP +NVFKQLLEAIGDTITNPVRMEPELNDVEPGEIQDTSTPRALATSLQAYTLGDVLENEKRA +LLVDWLKRNTTGDNLIRAGTPKGWVVGDKTGAAAYGTRNDIGIIWPPNDAPIILSVLSSR +NQEDADYDDQLIADATKSVIKTf +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. DOA1 TaxID=1126616 RepID=A0A150ZHX4_9BRAD +------EFEAYERESGGRIGVHAENLASGAKL-AWRADERFVMCSTFKASLAACMLARVD +RGEEQLAAMIPYREADLLEYAPVARQNLAAGMSVSEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSIGDTTSRLDHNEPELNRSRPGDPRDTSTPAAMAGNLRRLVLAEALSPASRA +QLTDWMVNCKTGANRLRGGLPASWKIGDKTGYNGKDAAGDIAVVWPKPDTPILITAYVQG +GAPSAAQIAAVFARIGRMVAD-- +>[subseq from] Beta-lactamase n=2 Tax=Oceanobacillus iheyensis TaxID=182710 RepID=Q8EMP8_OCEIH +----SEDLKKLEEEFDVRLGVYAIDTGADKEI-SYRENERFAYTSTFKPLAVGAVLQTKS +--DEELEETITYSEEDLVTYSPITEQHVDEGMTLVEIADAAIRYSDNTAGNLLLEAMGGP +DELETILRDIGDETIEMDRYETELNEAKPGDIRDTSTAKAMATTLQQYVLEDVLDADRRE +VLTNMLINNTTGDALIRAGVPDGWTVGDKTGAGGYGTRNDIGIIWPEDEEPIVIAIMSSR +DEEDADYDDKLIEKATEIVLQ-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sacchari TaxID=1399419 RepID=A0A560KDX9_9BRAD +------ELESYERDSGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAASVLARVD +RGEEQLAAMIAYGEADLLDYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVTSEALSPASRR +RLTDWMVNCKTGANRLRGGLPADWKIGDKTGYNGKDAAGDIAVAWPKPDAPVLIAAYTQG +GTPTAPQIEAVFARIGRMVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces flavovirens TaxID=52258 RepID=UPI0004C587B2 +------AFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGMHT +--LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP +RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEKRA +VLTDWLRRNTTGDALIRAGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR +ASPGAKPQDALIARAARVAL--- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004CC901F +--DAERRLAGLERASGARLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +DAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAMTRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI000477D042 +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDTSYDNALIAQATEVVIA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Saccharopolyspora sp. H219 TaxID=2492662 RepID=A0A426JWF2_9PSEU +------ELVELERRYDARLGLFARNTATGRTL-SHRADERVALCSTFKVYASAALLRAHG +LAGGYFERVIRYDAGQLVEYSPITEGRVGTGMTVGELCAAALQHSDNTAANLLLRELGGP +QAITEFARSIGDPATRLDRWEVELNTAIPGDERDTSSPRALADGLQRLLLGDALGAAERD +RLTAWMLGNTTGDARIRAGVPRGWRTADKTGGGSYGVANDIAVTWTETGTPIVLSLLTSR +PREDDTANNALLADATRLVVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis halotolerans TaxID=124252 RepID=UPI000346189A +--EFAAEFERLEEEFDARLGVYAVDTGTGEEV-AHRSDERFAYASTHKAFTAALVLDQNT +--PEEMEEVVTFTEDDLLEYAPITEQHVDTGMTLMEVTDAAVRYSDNTAANLLFEELGGP +EAFDDAMEAMGDDVIEANRVEPGLNDWAPGDDRDTSTPHAMAESLREFTLGDVLPEEKRS +VLTDMLVNNTTGDELVRAGVPEGWEVGDKTGAAGYGTRNDIAVLWPPEGEPIVLAVMSSR +DEENAEYDNALVAEAAEVVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=UPI0003914B0E +-dSLTKQIALIEQQSGGRLGVAVLDTQNHKQW-QYHGDDRFPMMSTFKTLMCANALYLAE +QKKLNLNATTKVKESDLVTWSPITEKLIGQEITVQKACEATMLMSDNTAANIVLHQIGGP +EQVSQFVRSLDDKVTRLDRFEPELNQAIPGDKRDTTSPSAMVELLNTLLLQDGLNQESQQ +QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALMWNSQRKPVILSIYLTQ +TQLDMAQRNRVINRVANLVFEQf +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2W6J0T0_STEMA +----TSDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus manasiensis TaxID=586413 RepID=UPI0005AA8553 +----EEIFKELEAEFDARLGVYAIDTESDQTV-TYRSNERFAYASTFKVLAAGAILQTKP +--KEELEKVITYSEDDLITYSPVTENHVDDGMELKEIMEAAIRYSDNTAGNLLLEELGGP +EGLEEILREIGDETIEVDRIEPDLNEAAPGDTQDTSTPQALAESLQKYVLSDLLPKDKRD +LLTDWITGNEAGDTLIRAGVPEDWKVGDKSGAGGYGTRNDVAVIWPPNQEPIVIAILSSR +DTTDADFDDTLIEKATEHVIE-- +>[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. Root102 TaxID=1736422 RepID=A0A0Q6NHU2_9RHIZ +------KIRRIEAKSGGRLGVACQIAGTSAQF-GYRENELFPMCSTFKTLAAALILHRVD +GGIEQLERSIKIPHNAVIANSPTTRKFAGGEMTVAQLCEAAVTVSDNGAANLLLESFGGP +PQLTAYLRSIGDSVSRLDRIEPELNESLPGDERDTTSPLAMVEDYGRLALGNSLSDKSRA +QLVDWLVANKTGDERIRAGLPKGWRCGDKTGTGDRGSTNDAAVIWPASGNPILMSVYLTG +TKQGLAKRNAVIASVSRVLVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia sp. LLH-Slr-6 TaxID=1564800 RepID=A0A097SRR9_9BURK +------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDQRDTTMPAAMATTLRKLLTAELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAVGPNGKPSRIVVISNT- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia transvalensis TaxID=37333 RepID=UPI0006874B6C +---TSKPFAELENQHTARLGVYGIDTGSGRTV-AYREGERFPIASTFKGIACGGLLRAHP +LSTGYFDQVIHYPATDLVANSPITEKRVDTGMTVAELCHAAITVSDNTAGNQLLKLLGGP +EGFTAFARSLGDTVTRLDRWETELNTAIPGDERDTTTPAALAADYRALVLGDVLAKPEQD +QLKSWLVANTTGTARIRAALPQDWTVGDKTGSPDYGGALDIAITWPPNRAPLVIAVLTAT +TNPNAQPNNPLVAAAAHN----- +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. Root568 TaxID=1736565 RepID=UPI0006F21CE0 +--AWNDALASIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD +QGKERLEARVHYPATDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDEVTRLDRTEPTLNEAAVGDPRDTTTPLAMLQTMQKLVLGNALSSMSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTAGSGTANDIGVLWPAGGAPVLVTCYLTR +SKASPEQRDAAIAQVARAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Silvibacterium bohemicum TaxID=1577686 RepID=UPI0006793777 +--TLPTALARLEQTSGGRLGVSVLDTANGTRT-GHRADERFPMCSTFKFLLASAVLQRVD +SHRETLDRAISIPPKPLVPYSPLTEPHAGGTMTISDLCHAALTRSDNTAANLLLESIGGP +SGITAFSRSIGDQVTRLDRTETSLNESLAGDPRDTTSPRAMADDLKSVLLGNVLSSVSRD +QLTQWMEANLTGLERLRANLPQGWRAADKTGSNGEHTTNDIGVFWPVGRPPVIVTAYITQ +CPGQESKRGAMLAEVGRLV---- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. CNZ304 TaxID=2512143 RepID=A0A4Q8C0C2_9ACTN +-----REFERLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYASTHKALTAALVLQQNT +--PEEMEEVVTFTEEDLVDYSPITEQHVDTGMTLMEVADAAVRYSDNTAANLLFEELGGP +DAFEDELEAIGDDVTDPERIETELNDWTPGDTSDTSTPRAMAGNLREFALGDALPEDRRE +VLNDLLVNNTTGDALIRAGVPEDWRVGDKTGAASHGTRNDIAVIWPPEGDPIVLAVMSSR +EAEDAEYDDALVARAAEVVAE-- +>[subseq from] Beta-lactamase n=3 Tax=Rhizobium meliloti TaxID=382 RepID=Q92Y20_RHIME +-hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD +KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAINLLLESFGGP +PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA +QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHANNNDIAVAWSPNRGAIVVATYCEI +PTISADERNAVVAEVGRLVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas sp. WN018 TaxID=2032624 RepID=UPI000BAB2ED8 +--NLLTEVDRIERQLDARVGFAAYDLETEQRW-EYNADQLFAMSSTFKTLACASLLQRVD +EGSEQLERRVKVSASDIVTYSPVTEAYADNRISLFELCEATMATSDNTAANLILQAIGGP +QAVTEFVRELGDSVTRLDRWETELNEAVPSDERDTTTPNAMVSNLEKLVVGNALSPQSKN +QLREWLVNNEVADGLFRSQMPDEWVIGDRTGAGGFGSRSITAVIWPPERKPIIVAFYITE +TTASFEDRNTAIAELGDVI---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. KE1 TaxID=1638939 RepID=A0A0H1ADI5_9ACTN +------ALRTLERKYDARLGVYALDTGTGKTI-GHRAGERFAFCSTFKTLAVAAILDRNP +--LGHLDKHVTYTRDDINSISPVTRKNVDKGMTVGQLCDAAIRYSDGTAANLLLRDLGGP +ERLTDYFRELGDTVSRLDHYEPELHRVRPGDPADTTTPRAIAADYRTVVLGDTLARDRRA +LLTDLLERNKTGGNRIRAGVPKGWRVADKTGTGQYGRANDIAIVWPPASGPLVLAIMSER +SGREARPSEALIAEATEHVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Actinobacteria TaxID=1760 RepID=UPI0002EB480C +------AFAALESTYDARLGLSVLDTGTDRVV-AYREHERFPMASTFKGLACGALLQAHP +LATGYFEQVIRYTAADIVVNSPETEQHIDTGMTVTALCDAAITQSDNTAGNLLLRLLGGP +EGFTAFLRTLGDQVSRLDRWEPELNTAVPGDERDTTTAAALAADYRALVVGTALAEPERA +QLAAWLKASRTGAKRIKAGLPADWTIGDKTGTPAYGSALDVAVAWPPGRAPLVLAVLTTR +TEKDADPVNELVAEAAKTAV--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Curtobacterium TaxID=257496 RepID=UPI000DA7FD4B +--ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTIKVFIAAAVLDASS +--DTDLATVVHYDRGDLLEYAPVTREHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTSVDRAEPDLNQAIPGDRRDTTTPERFAANLRTVLLGDALDAADRR +VLLEAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR +ADPGAEPSDALVAAATRTAV--- +>[subseq from] Beta-lactamase 1 n=1 Tax=Streptomyces sp. F-1 TaxID=463642 RepID=A0A1K2FJX0_9ACTN +------ELGDLERDYGARLGVYARNVRTGRVL-AHRAGERFAHCSVFKAFAAAAVLRDRS +-GCAPLDKVIHYPPHDILPNSPRTEENQETGMTVADLCAAAIQYSDNTAGNLLLQQVGGP +AGLTGFFRSLGDRVSRQDRWEPELNTAIPGDLRDTTTPEAIATSLERLTLGRALPAPDRE +RLVTWMKGNTTSGARFRAGLPEGWTLADKTGTGFYASAHDIGVAWTTRRTPVVLAVLSTK +DEKDAPVDEALIREAARIAAR-- +>[subseq from] Beta-lactamase n=1 Tax=Luteimonas sp. 100111 TaxID=2006110 RepID=A0A290XCD2_9GAMM +--TLDAALAALEQAAGGRLGIAVLDTGTGRRL-GRREEERFPMCSTFKALLAGAVLHAVE +RGHVRLDQPVDVAAGDLVPYSPYVETRLAQGARVDDLCRATVTLSDNAAANLLLPLVGGP +SGLTAFLRALGDPVTRLDRWEPDLNEAARDDPRDTTSPRAMVDSLQRLLFGDVLRAPLQA +VLAAWLIENRTGEARIRAGVPAGWIVGDKTGTCGAGTAADVAVLYPPGRAPLLLAVYVHG +AGVSGPAIDALHADVARAVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces chilikensis TaxID=1194079 RepID=UPI001408A6A1 +----VARLRELERRHGARVGVHAWNTVTGTTV-RHRADERFPILSVFKTLAAAAVLRDRD +RDGEFLDRRIRYTEAQLVENSDVCEANLATGMTVRELCAAAVQWSDNTAGNLLLRQIGGP +HGITRFARSLGDPVTRLDRWETELNSGEPWRETDTTSPGAIAATYARLVLGGALERPDRE +LLTSWLLGNRTGRTRLRAGLPPEWTIADKTGAASYGSLNDVGVVWTEDGTPLVMAVLTTK +PERDAPRQDVLLEDVARILAD-- +>[subseq from] Beta-lactamase n=1 Tax=Terribacillus saccharophilus TaxID=361277 RepID=A0A268HGY2_9BACI +-----ASFSSLEETYDARLGVFAIDTGSGRTV-AYRENERFGFASTHKALSVGVLLQQKS +--IEDLNKRVMFTGDDLVNYNPITEKHVDSGMTLKELSEASISYSDNTAANLIFEEIGGP +DGFEDGLRKIGDQVTNSERIEPDLNNTQPGNTRDTSTPKAMAESLREYALRDHLSADKRQ +LLVDWLKGNTTGDALIRAGVPKDWEVGDKTGAGSYGTRNDIAILWPPDEEPIVLAIMSDH +DEADANANDDLIAEAAEAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces glaucescens TaxID=1907 RepID=UPI000A385B89 +-----GRLRALEREYGAKLGVYAHNVGTGRTI-RHHADDLFPICSVFKTLAAAAVLRDLD +RDGEFLARRIHYTEADLVDGSDETRKHLAEGMTVAELCDVTIRYSDNAAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYARLVLGDALPGADRE +LLKHWLLNNTTSLDRLRAGVPPTWTVADKTGGGDYGVNNNVGIAWTPDGTPVVLAVLSRK +SDPAAVRENALIAKTAKVLTE-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia asteroides NBRC 15531 TaxID=1110697 RepID=U5E5U8_NOCAS +------AFAALESTYDARLGLSVLDTGTDRVV-AYREHERFPMASTFKGLACGALLQAHP +LATGYFEQVIRYTAADIVVNSPETEQHIDTGMTVTALCDAAITQSDNTAGNLLLRLLGGP +EGFTAFLRTLGDQVSRLDRWEPELNTAVPGDERDTTTAAALAADYRALVVGTALAEPERA +QLAAWLKASRTGAKRIKAGLPADWTIGDKTGTPAYGSALDVAVAWPPGRAPLVLAVLTTR +TEKDADPVNELVAEAAKTAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinoplanes philippinensis TaxID=35752 RepID=A0A1I2N0T1_9ACTN +----APSFSGLEQRFGARLGVYALDTATGRTV-AHRANERFAHASTVKALQAGVVLRGAS +--DDDLRTVVRYERSDLLGHAPITTEHVDTGMSLGDLLAASLRYSDNTAANLLFEHLGGP +DALERELRSLGDRTTSVDRIEPQLNEARPGDTRDTSSPRALGATLQTLVLGDALPVARRD +QLTTWLRGNTTGGPYIRAGVPAGWVVADKTGSGGYGTRNDIAVVWPPAGAPLVIAVMSDR +GVRDAPSADSLIAEATAKVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0005349BCD +--DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDATT +--DAELDQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEQELKGIGDNVTDAARYETELNEATPGDRRDTSTARALTEDLQEYAVDDALDPTDRD +ILNAWLRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEPDASFDNALIAEAAGVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Comamonas sp. CAH-2 TaxID=2605745 RepID=UPI0012ADDAD1 +--HWSQAMAQIEQDAQGRLGVAMLDTGSGLAL-GWRQDERFAMCSTFKLPLAAWVLALVD +QGRERLDARVQYSEADLVEYSPVSGPKAGAGLTVGELCSATVSLSDNSAANVLLARHGGP +AALTAWLRSQQDSITRLDRNEPSLNEAAVGDERDTTTPLAMLHTMQRLVLGTALSPSSRA +TLQRWLIETSTGDQRLRAGAP-GWKVGDKTGTSGSGTANDIGVLWPPGGAPVLVTCYLTQ +STARPEQRDAAIAQVARAVLT-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia takedensis TaxID=259390 RepID=UPI000A02BF59 +--DAAAAFADLETSAGARLGVHAVDTADGQVL-AYREHERFPMASTFKGLACGALLREHP +LSSGYFDQVIRYGADEIVDASPATSRHLDSGMTVAELCEAAITLSDNTAGNQLLKLLGGP +AGFTAFLRSLGDQVSRLDRWETELNTAVPGDERDTTTAAALTADYRALVVGDVLGAPERE +RLTSWLVANTTGDKRIRAGLPAEWRVGDKTGSPAYGSALDVAVTWPPGRAPLVLTVLTTK +PDRDATADNALVAAAARLAVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodobiaceae bacterium TaxID=2026785 RepID=A0A2A5EVG5_9RHIZ +--NLIETIKAVEKRIGGRVGAAIYDTETGRNW-EYRARERFPLSSTFKAFACAAVLSRVD +QGAEQLDRVIEIQESDLVTYSPVTEKRIGTEMTLSDLCNAAVTLSDNTAGNIILQSLGGP +EGFTNYMRTIGDPMTHLDRWETTLNEGAPNDMRDTTTPQAAANSLHTVLLGDVLSASSRQ +QIXDWMRXDXVAGALXRSAVPTXWQXADKTGAGGHGSRSIIAVMWPPQRKPIIATVYMTX +NSAEFADRNAAIAEIGAAIVS-- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_021 TaxID=2175665 RepID=A0A2W1RNS5_9MICO +---ATRAFSALEAEHAARIGVVAVDTADGATV-AHRAGERFPFASTAKVFIAAAVLDDAA +--GSDLAAVVPIGPRDLLSYAPVTSRHVGTGMTVRALLDAMIRTSDNTAANLLVSRIGGP +AAVQSWLRGIGDDVTRVDRVEPDLNAAVPGDERDTTTPSQFAADLRTVLLGDRLDPDDRA +LLVDLMRGTTTGAGTIRAGVPAGWSVADKTGTGSYGVRNDVGIVTPPGRAPVVLVVMTSH +DTADAQPDDALVAAATRTAID-- +>[subseq from] Beta-lactamase class A/beta-lactamase class A CARB-5 n=1 Tax=Labrenzia marina TaxID=281252 RepID=A0A2S3UX95_9RHOB +---LARAVEDISSRLPARVGVAVIDMETGTRW-AHKGDERFPTNSTFKVFLCAALLDAGV +RGTADPDSRVTIRRGDIVSYSPVTEKRIDGAVTLRELCGITVTISDNAAANLVMKEIGGP +QALTAYLRGIGDSVTRADRWEPDSNSGIPGDDRDTTSPNAAAETLKKLVLEEALPADARQ +TLTNWLTGNKVGDATLRAGLPDNWRIADKTGAGANGSRNNIAVIWPDGRAPVVIAVYITE +TSASFEARNGAIAEIGAALAD-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013102FFA +---TATDFAALEKACAGRLGVSLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAEGDPRDTTTPAAMAMTLQRVVLGEVLRPASRQ +QLADWLIDNETGDECLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRAMVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium centrolobii TaxID=1505087 RepID=A0A176YAR2_9BRAD +------ELASYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAKIPYGQADLLEYAPVAKQNLAAGMSVVDMCRAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPVAMAGNLRRLVLGESLSPASRG +QLTDWMLNCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPSPDRPILIAAYTQG +GTPTAAQIEAVFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis mediterranei (strain S699) TaxID=713604 RepID=G0FMS0_AMYMS +-----PDFAPLERSFDARLGVYALDTGSGREI-THRADERFGYASTHKVFSAGAVLRRTS +--LDGLAKNLTYTRADLQPNSPVTEKHVTTGLSLREAMDAALRYSDNTAANLLFRELGGP +AGLAAALREIGDTTTHADRIEPGLNDLAPGDVRDTSTPRAMAGSLRAFALGPALPPEKQT +VLTDMMRANTTGAALIRAGAPAGWAVADKTGSGSYATRNDIAVVWPPGRAPIVLIVMSSR +QAESADHDDRLIAQAAKLALDAf +>[subseq from] Beta-lactamase n=2 Tax=Xanthomonas TaxID=338 RepID=A0A5D1A8F8_9XANT +--TLPRRLAEIERRSGGRLGVSLLD-GGGATLgGQRQNERFPLCSTFKFLLAGAVLQRVD +RGELALERRVPVRKADLLANAPVSERHVGGTLSVVELCRASMIYSDNTAANLLLPLVGDP +PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPCDTTTPAAMAATMRALLLGEVLQPVSRQ +RLIAWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG +ATVDSAARDATLKAVAQAVVA-- +>[subseq from] Beta-lactamase AST-1 n=1 Tax=Luteimonas sp. 9C TaxID=2653148 RepID=A0A653WC68_9GAMM +--SLDDALAALEHAAGGRLGIALLDTGTGRRF-GRRDDARFPMCSTFKALLAGAVLHAVD +RGRVRLDQRVDIGAGDLVTYSPYVETRVADGARVDDLCRATVTLSDNAAANLLLPLVGGP +PGLTALLRELGDPVTRLDRREPELNEAAAGDPRDTTSPRAMIDSLQRLLFGDALRPPSQA +VLAAWLIENRTGDARIRAGVPGDWRVGDKTGTCGAGTAADVAVLYPPGRAPLLLAIYVHG +AQLDGPAINALHADVTRLLV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNQ329 TaxID=1298879 RepID=UPI0004883A28 +-----RQLAELEREYDARLGVYAVDTGSGREV-AHHADERFPYASTFKALAAGVVLRTRP +--AAELDRVLTYSADDLIAHSPVTAEHVATGMTLRDLCEAAVRSSDNAAANLILAELGGP +AGMDAELEAIGDDVTRMVRNEPELSRWTPGDTRDTTTPRALARGLRTFVLGDALDKPARG +LLTTWLRTHTTGDTLIRAGVPSAWTVGDKTGTGSYGARNDIAVLWPPDRAPLVVAIMSHR +TERDAEADDELLAEAASEVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. IB2014 016-6 TaxID=2517818 RepID=A0A5C8QDC9_9ACTN +---TKAAFARLERRFDARLGVYAIDTGNGRSI-THRPDERFAYASTCKALLAAVMLDRYS +--LRQLDRLVRYDRNDLAGYSPITEKHIATGLTLRELCDATVRYSDNGAANLLFRELGGP +KSLQSALASIGDRVTRCDRYEDALSAAVPGDLRDTSTPRALATDLRAYVVDDALAPDKRA +VLTDWLKRNTTGDKVIRAGAPDGWQVGDKTGTGGYGTRNDIAVVWPPKAAPIAIAVLSRR +DFKDAEPDDALIAEAAGITL--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium lusitanum TaxID=293958 RepID=UPI0013DBFA35 +----EARLAALESKHPGRICVSILDMANGKRI-EHRAGERILMCSTFKALAAALVLARVD +KGQEKLDRRIRYTKSDLVDGSPATKAHVRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP +QALTAFCRSLGDEITRLDRTEPTLNYDRQDDERDTTTAAAMLENLRRLLFTDVLSAASRS +QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI +PTIAADERNAIVAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=UPI00083177FA +---FTGAFRKLEHAYDARLGVYAIDTGTGREV-AYRDGERFAYASTFKALAAGAVLRKYS +--LSGLDRVIRYAKDDLVDYSPVTEKHVKTGMTLGALCDAAVRYSDNTAANLLFDVLGGP +KGLDAMLEKMGDDVIQMENEEPELSRWVPGETHDTSTPRAMAEDLRAFVLGDALGKPERT +QLTKWLRTNTTGDELIRAGVPKGSVVGDKTGNGSYGARNDIAVVWPPDSAPIVLAIMSWR +GDKDTTFDNKLIADAASVVAD-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=UPI00112F1E65 +--STARDFATLEAASGGRLGVTLLDTGSGQRI-GHRQDERFPMCSTFKFALCATVLRLAD +QGKLSLDRRLAMTTQDLLSHAPVTARHVGKDVTVRDLCRATMVTSDNPAANLLLRVVGGP +AGVTAFLRASGDDVTRNDRYEPEVNRFAPGDPRDTTSPAAMAASLQRLVLGERLQPASRQ +QLADWLIDNETGDAHLRAGLSNAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ARLDGAGRNDILRQVAVIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia vermiculata TaxID=257274 RepID=UPI0008326F9E +-----DEFQGLEARLHGRLGVYALDTGTGRAV-EYRADERFPYASTFKALAAGAVLSKLT +--PADLYRHVTYSRADLLPNSPITEKHVDEGMTISEILDAAVRYSDNTAGNLLFAELGGP +KGLQQQLRDIGDTTTQSDRTETSLNEAIPGDERDTSSPQAMAEDLRHYVLDPAVDAEDRE +ALTGLLRTNTTGAALIRAGVPADWVVGDKTGGGEYGTRNDISVVWPPGRAPIVLTVLSTR +DRPDAEFDDSVIARAATIAV--- +>[subseq from] Beta-lactamase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7N1W4_9BACT +-------FGSIERQVAGRLGVAALDTATGRRL-AYRADERFAMCSTFKWLLGAQILSRAD +AGAEQLSRVVPYGETDLLEYAPVTRAHVREGMTISELVSAAIRFSDNTAANLLLHTIGGP +ASFTAYLRQLGDRITRLDRVEPDLNSAIPGDVRDTTTPKAMVANLGVVLLGDHLGRAARD +QLIAWLVGSTTGTDKLRAGLPATWRVGDKTGMGGHGATNDVAVAWPVNRGPVLVAAYLAD +TEADVAGRNDALADVGHAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces somaliensis TaxID=78355 RepID=UPI00049547AF +--RVEGRLRALERAHGARLGAFAYDTGTGRTV-AHRADELFPMASLFKAVAVAAVLRDLD +RDGEVLARRLHYTERYVREFSPVTERNLANGMTVAELCDATLTRSDNTAGNLLLRELGGP +TAVTRFCRSVGDGVTRLDRWEPELNSAEPWRTTDTTSPRAIGRTYGRLLLGDVLAAPDRE +RLTRWMLANKTSDERFRAGLPADWPLADKTGGGGYGSNNDAGVAWPPGRPPVVLAVLTTR +FAPDAAADNALVAEAAALLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=UPI0002D47941 +--MLRAQWAEIERGTGGRLGIDLLDSATGWRL-GQREDERFPMCRTFKFVLAAAVLQRVD +QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP +AGLTGFLRGIGDAQTRSDRYEPETNRFAAGDPRDTTTPAAMVATLRTLLLGDALQPSSRQ +QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGSDTRNDIAILWPPKGAPLLLTTYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Microbispora sp. GMKU363 TaxID=718014 RepID=UPI0006E38E5C +--EARRKLRALEAAFKGRIGAYAVDTASGKTV-AYRSGERFPLLSTFKAVAAAAVLHKAR +TDPGLMDRVVRWSRDDLKPHSPITEKHVGDGMTVARLCEAAIRYSDNTASNMLLKQIGGP +AGLTRYFRTLQDPISRLDRWESELNDWNPKERRDTTTPESMARSLHAVTIGDALDAKDRD +RLNGWLTANTTGDARIRAGLPKDWTIGDKTGTGGYGTANDIAVVWPAEAAPIVMAIYTNR +RAADAPGDDKIVAETAAILV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. LLH-Irr-21 TaxID=1564876 RepID=A0A097SRT0_9ACTN +-----VRVKDAEDQWGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNKGDHVTRLDRWGPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQA-------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas sp. SGNA-20 TaxID=2493088 RepID=UPI000F639CDA +----APDFAALEAASQGRLGVAVLEAGNGRYLaGHRADERFPMCSTFKALLAAAVLARAD +RGALDLDERLPVRAADLVPHAPVTRRHVGKDLGVRDLCRAIVTISDNTAANLLFARIGGP +AALTAFLRGLGDTVTRSDRLEPEMNGFAPGDTRDTTSPRAMATSLGRCVAGAVLAPASRL +QLADWLIDNTTGDDCLRAGIGPEWRVGDRTGSNGTDIRNDVAVLWPLGGSPWVVAAYLEG +SRVDSAARDAVLARAGQLAV--- +>[subseq from] Beta-lactamase n=1 Tax=Kushneria phyllosphaerae TaxID=2100822 RepID=A0A2R8CPZ3_9GAMM +--EVKRKLEALEQRHGGRVGVALMNVATGETV-SHRGDERFLFNSTGKVFIAAAVLAQVD +RDRISLDQRIEVKTSDLTGWTPITEKHLGGPMTIAELCQAAVAWSDNAAANLLIERLGGP +ADITAFLRSIGDITTRLDRTEPTLNEDHDGDERDTTTPLAMMQTLRTLLLGEALSPSSRH +QLAAWMIEGKMGDARLRAGMPADWLVGEKTGTNSVGNAADIGIAWPSDRGAVIAIAYVYL +PQADKAQRDQVIKDIGTLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID1046 TaxID=2690249 RepID=UPI00136871B4 +-----AGLRALEREYGARLGVYALDTASGRTV-AHRADELFPMCSVFKTLAAAAVLRDLD +HDGSHLAKRIHYTLQDVTDGGSITEKNIANGLTVAELCSAAIAQSDNAAGNLLLRELGGP +TAVTRFCRSLGDRTTRLDRWEPELNSAEPSRVTDTTGPRAIGRTYARLALGDALDPGDRE +LLNRWLLSNTTSGDRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRQPIVLAILSTM +PEATAPRDNTLIARTAKLLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LF90_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A3D0GCZ0_9GAMM +-----ADFAALEKASGGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKFALSAAVLHLAD +QGRLSLDRRLPVRQQDMLSHAPVTKRHVGKDLTVRDLCRATMVTSDNPAANLLLGVVGGP +AGVTAFLRANGDAVTRNDRLEPDMNRFAPDDPRDTTSPAAMAASLQRFVLGEVLTPASRL +QLADWLIDNETGDTRLRAGLSPAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ATVDDAGRNDTLRQVAVIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NBRC 110028 TaxID=1621260 RepID=UPI0006E157CD +-----GELKALEREFDARLGLYAIDTGTGREV-AYRAGERFGFHSTHKALTAGAVLRRYS +--LGGMDKVITYSRDDLIDNSPITEKHVDTGMTLRELCDAAVRYSDNTAANLLFDVIGGP +KALQREVRRLGDDITRMDRVEPDLSRWTPGETRDTTTPRALAGDLRAFVLGDVLRKPERA +KLATWLRTNTTGDALIRAGVPEGWVVGDKTGSGGYGARNDIAVVWRPGAAPIVMAVMTNR +GEEDDAHDDKLIAKAASVVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CS090A TaxID=2162710 RepID=A0A2T7KKY9_9ACTN +---TDRAFAELERKFDARLGVYAIDTGDGRTV-THRPDERFAYASTCKALLSGAVLAKKT +--LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP +RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYTLGSALPAEKRA +LLIDWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVWPSGGAPIALAVLSRR +DIKNAETDDALIAGAAKVALGAf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. cf386 TaxID=1761904 RepID=A0A1H0SH49_9ACTN +------SLRALERKHDARLGVYALHTGTGTTV-AHRADERFAFCSTFKTAAVAAVLDRNP +--LSHLDKRVTYGWNDINSISPVTRKNVTQGMTIRQLCDAAVRHSDGTAANLLLRDLGGP +QRLTAYLRELGDTVSRLDHYEPELHRARPGDPNDTTTPRAIAADYRTIILGEALATDKRA +LLTDLLVRNTTGGNRIRAGLPKGWRVADKTGTGTYGRANDIAVVWPSGSEPLVLAIMSER +AEREARPSESLIAEATEQIA--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas prunicola TaxID=2053930 RepID=A0A2N3RNH9_9XANT +--ALRARWVEIERRSGGRLGISLLDTATGQRI-EQRQDERFPLCSTFKFLLVAAVLQRVD +RGELRLDRQVPIRAEDMLSYAPATKPHVGGSLSLAELCQAAMIFSDGVAANLLLTQVGDP +VGLTAFIRTLGDTQTRSDRNEPSMNNFALDDPRDTTTPAAMLGSMRAVLLGDALQPASRK +RLTDWMIDNRTGDDCLRAGFPQGWKVGDKTGNNGTDSRNDIGIVWVPGQAPLLLTTYLNK +ATVDADARDAALKAVAQAVAAWw +>[subseq from] Beta-lactamase n=1 Tax=Glycomyces fuscus TaxID=1407559 RepID=A0A2A6F543_9ACTN +------EFERLEEEFDARLGVYALDTGTGRVV-EFQADERFAYCSTFKALAFGAVLDRTP +--VDELDRVVTFSEADLVFHSPVAREHVATGMTLREIGDAALRHSDNTASNLLVEELGGP +KALEEALRGIGDDVTRVDRLAPEMAEAVPGDDRDTSTPRAMATSLRAFALGDVLPEDGRE +VLVDMMRANTTGDDLIRAGVPEGWTVGDKTGACGYGTRHDVGVLWPPEGAPVVLAVMSSR +DEAGAGYDDALVARATETVV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. M41(2017) TaxID=1955065 RepID=A0A1V9K156_9ACTN +----APSFARLEREFDARLGVHALDTGTGKAV-AYRPDERFAFASTYKALAAGAVLRRNT +--PAGLERVVPYTRAELVAHSPVTERHVESGMSLRALCDAAIRYSDNTAGNLLFDELGGP +KGLQAELAGLGDTTTRADRYEPALNEATPGDPRDTSTPRALTSALYAYTLGGVLDSEKRA +LLLDWLGRNTTGGALIRSGVPAHWKVGDKTGNASYGTRNDIAVVSPPGAAPILLAVLSSR +AARDAASDDRLIARATEVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces triticirhizae TaxID=2483353 RepID=A0A3M2M2Q1_9ACTN +--SAEEEFGALEGEFDALLGVHAVDTGTGREV-AHRADERFAYASTFKALLVGAVLDEHG +--ANGLDEVITYTADDLLDNSPVTENFVGSGMSLRELCAATLWYSDNAAANLLLDVAGGP +EALEAWLRQLGDDTTRMDRWEPDLSEGIPGDDRDTSTPRALAADLRALLLGDALGDAERA +LLRAWMETNTTGETLVRAGVPAEWTVADKSGTAGYGGRNNIAVVWPDDGEPIVLAVMSRR +DQPGAERDDALIARAATVAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00047F8F47 +------GFRRLEKRFDARLGIYAIDTDTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DELDASYDNALIAQATEVVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces californicus TaxID=67351 RepID=UPI0004BE5A2F +----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLGKYS +--LDGLDRRVTYTRKDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +RGMDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLDGALPAPERE +QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR +ATKDAEPSDELIAEAASVVAD-- +>[subseq from] Beta-lactamase n=10 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q9F279_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000377FE18 +--DLHHEFRRLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAVADAAVRYSDNTAGNLLLRHLGGP +ERFEQELKGIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPADRD +VLNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVLWPPDRAPVVLAVLSSR +DEPDASFDNALIAEATEVVLA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL WC-3742 TaxID=1463934 RepID=UPI000D13EEB3 +---TARHLADLEREHGARLGVHARNLRTGHVV-QHRAGELFPMCSVFKTVAVAAVLRDLD +RDGEFLARRLHYTRADTEAGAPVTGQNLAEGMTVAELCAAAIDHSDNAAANLLLRELGGP +AAVTRFCRSIGDRTTRLDRCEPDLNSAEPDRTTDTTTPRAIARIYRRLLLGHALPPAKRH +RLTTWMLGNTTSTHRFREGLPADWRLADKTGTGSYGTTNDVGIAWTPDGAPVVLSVLSTK +PDPKAPKDDALVAEAAALLA--- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora pisi TaxID=589240 RepID=A0A495JT32_9ACTN +--KAEREFARLETEFDARLGVYAIDTGSGRTI-THRADERFAFVSTYKALIAAAVLDETS +--TAGLNKVIRYFKEDLVSHSPITEQHVQTGMTLRAVADAAVRYSDNTAGNLLFKQLGGP +NSFERALRGIGDQVTESARLETGLNEAIPDDERDTSTPRALASDLRAYAVDTALSRDDRT +ILTEWLTGNTTGASLIQAGVPAGWQVGDKSGAGGYGTRNDIAVVWPPKGAPIVLAILSSR +SESDATYDDALIAQAAEATI--- +>[subseq from] Beta-lactamase n=6 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q9RBQ1_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1P740_9ZZZZ +--------------------------------------ERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=UPI0009E930AF +----SNRFAEIERRYRGRVGVYVPASGTAAAI-AYRADERFAICSTFKAPLVAAVLHQYP +--LAYLDQRVTFTKADITSPSPIAEQHVDTGMTVGELCDAAIRYSDNTAANLLLNRIGGP +AGLTAYLRSLGDSTSRLDQAEPELNGNPPNDERDTTTPRAIAGVFQQLVLGDALPQDKRT +LLIDWMARNTTGGKRIRAAFAADWKVSDKTGSGDYGRANDVAVVWSPAGVPHVIAIYTDM +AAYDAQPDEAFVADAARIVAS-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00073963CB +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces antioxidans TaxID=1507734 RepID=A0A1V4CZB3_9ACTN +--AATAAFTKLERSYDAHLGVYAIDTGSGHEV-AYRDGERFAYASTFKALAAGAILRKYK +--LSGLDRVIRYAKDDLVDYSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLLDQLGGP +KGLDATLEKLGDDVITMERPEPELSRWVPGETHDTSTPRAMAEDLRAFVLGDVLGKGERA +QLTKWLRTNTTGDELIRAGLPKDWQVGDKTGNGSYGARNDIAVVWRPHAAPLVMAIMSYR +GEKDTPFDNKLIADAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces cyaneofuscatus TaxID=66883 RepID=UPI0013DA9593 +---TDRAFAELERTFDARLGVYAVDTGDGRTI-AHRPDERFAYASTCKALLSGAVLAKKT +--LPQMERLVRYGQEEIISNSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP +RGLQDALRGLGDRVTRCDRYEVALSDAIPGDLRDTSTPRALAADLRAYTLGSALPAEKRA +VLIDWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVWPPGGAPIALAVLSRR +DIKNAETDDALIAGAAKVALGAf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=A0A5C6HSA2_9ACTN +--EAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +QNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae S611 TaxID=1399146 RepID=V5AG92_ENTCL +------AIARLEEKLHARIGIAVIDTASGKSV-SYRGDERFPLNSTHKALLCGALLSKVD +KGEFALSDITQFSKETLVDYSPVTSKFVAPKMSWQQVCSAAIEYSDNTAANLVAQKLGGP +QKVTAFFAGLGDNVTRLDRKEPELNSAVPGDLQDTTTPLAVSRTLEKLTLGDALKPESRA +QLVQWMKDDKVADALLRASLPSGWKIGDKTGAGAYGSRSIISVVWPKKGQPIIVSVYITQ +TEATLAQSNDAIARIGKSIFE-- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. Root275 TaxID=1736508 RepID=A0A0Q9DTL9_9BURK +--QWNDTLAGIEHFAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD +QGKERLDARVHYAAADVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANLLLARHGGP +AGFTAFVRSLGDGTTRLDRTEPTLNEAKVGDPRDTTTPLAMLQTLQKLVLGDVLTAPSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVLWPPGGAPVLVTCYLTR +SKAKPEQRDAAIAQVARAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_054 TaxID=2175632 RepID=A0A2W1TAK4_9MICO +--ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTIKVFIAAAVLDASS +--DADLATLVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP +HAVERWLRRIGDRTTRVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGREPVVLVVMTSR +ADPGAEPSDALVAAATRTAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium organophilum TaxID=410 RepID=UPI000D5C3DAB +----EPDWTAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKVLAVAAVLARVD +AGRETLDRIVTYGPGDLLSYAPVTRKALEAGMSVADLCAATLVWSDNAAANLLLADLGGP +AALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRILLGTTLSPASRD +RLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGDNGTVNDVAILRPPGRAPILVAVYVTG +STASPDACAAAYAEIARLIA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Hydrogenophaga sp. Root209 TaxID=1736490 RepID=A0A0T2ZME9_9BURK +---LQDSLREIEAMARGRLGVHIIDTATGREH-GWRSDERFLMLSSFKLLASALVLARAD +RGEESLERRIRFRQQDLVTWSPVTEKHVGGELSLAQLCEATITTSDNTAANLILASYGGP +AALTAFARRLGDTVTRHDRTEPELNRAASGEPLDTTTPRAMAHTVRKLLLGDALAPASRE +RLLQWLLANTTGGKRLRAGAPAGWRVGEKTGTAGD-DANDIGIALPPQRAPLIVTAYLAE +SATDGATRDAALASVGRLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Amylibacter sp. SFDW26 TaxID=2652722 RepID=UPI00126196C6 +---VQKTVSNWEAKLGARIGVLLRDVSSDWEI-AMRADERFPMSSTFKALLCGAVLARVD +AEQEDISRLVNFQEDDLVSYSPVTEEHVQVGMSVGSLCEATITISDNTAANLLLETMGGP +KGLTDFLRKIGDATTRLDRWETELNEGTPGDLRDTTTPRAILSTLETLLLGDVLKPASAK +QLAQWMIDDQVADALIRAHLPDGWVIGDKTGAGGFGSRSIIAFLQVPDGGQYLAAIYLTE +NDADFQLRNKIVSDIGRALI--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=A0A0Q2QZX4_MYCGO +----SNRFAEIERRYRGRVGVYVPASGTAAAI-AYRADERFAICSTFKAPLVAAVLHQYP +--LAYLDQRVTFTKADITSPSPIAEQHVDTGMTVGELCDAAIRYSDNTAANLLLNRIGGP +AGLTAYLRSLGDSTSRLDQAEPELNGNPPNDERDTTTPRAIAGVFQQLVLGDALPQDKRT +LLIDWMARNTTGGKRIRAAFAADWKVSDKTGSGDYGRANDVAVVWSPAGVPHVIAIYTDM +AAYDAQPDEAFVADAARIVAS-- +>[subseq from] L2 family class A beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6B8GSQ4_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium radiotolerans TaxID=31998 RepID=UPI00040171C5 +----EPDWTAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKVLAVAAVLARVD +AGRETLDRIVTYGPGDLLSYAPVTRKALEAGMSVADLCAATLVWSDNAAANLLLADLGGP +AALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRILLGTTLSPASRD +RLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGDNGTVNDVAILRPPGRAPILVAVYVTG +STASPDACAAAYAEIARLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium intermedium TaxID=28445 RepID=A0A1E3SDB1_9MYCO +--DLSERFAELERRYESRLGVHVLADGDTAPI-SYRADERFAFCSTFKAPLAAAVLQRNP +--LAYLDKVITYTRDDIRSTSPITEQHVDGGMTIRQLCDAAVRYSDGTAANLLLAEIGGP +AGFTQFLRSLGDNVSRLDQLEPELNRDAPNDERDTTTPRAIAGVFQQLVLGEALPADKRG +LLTDWMVRNTTGDKRIRAGFPPDWKIADKTGSGDYGRTNDVAVAWSPSGASYVVAIYSDC +VTYNAPYNDAIVAAAAKIVAS-- +>[subseq from] class A beta-lactamase n=1 Tax=Sciscionella marina TaxID=508770 RepID=UPI00035E9A7E +-----DRLRALERAHQAHLGVYARNLRTGATA-THRAGERFGMCSTFKTLAASAIMRDRD +GDGTFLDRIVHYTDEDLVENSPITENHVRGGMRIAELCHAAICYSDNTAGNLLLRQIGGP +AGVTRFCRSLGDRVTRLDRWETELNDIAPGDPRDTTTPRAIGEDYARLALGTALDPAHRA +RLTGWLIGNTTSAKRFRTGLPDSWLIGDKTGSGAYGSGNDVGIAWTGAGTSLVLAVLTRK +HEPEAGYDDELIAEAARILAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=UPI00052AA8FC +-dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDHFPMMSTFKTLMCANALYLAE +QKKLNLNATTTVKESDLVTWSPITEKLIGQEITVEKACEATMLMSDNTAANIVLHQIGGP +EQVTQFVRSLDDKVTRLDRFEPELNQATPGDKRDTTSPSAMVELLNTLLLQDGLNQESQQ +QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPVILNIYLTQ +TQLDMAQRNRVINRVANLVFEQf +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000DA80525 +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHHQDERFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Carbapenem-hydrolizing beta-lactamase SFC-1 n=1 Tax=Serratia fonticola TaxID=47917 RepID=UPI0002604934 +-----DKLKRLENDFGGRIGVYAIDTGSNKTF-GYRANERFPLCASFKGFLAAAVLSKSQ +QQEGLLNQRIRYDNRVMEPHSPVTEKQITTGMTVAELSAATLQYSDNGAANLLLEKIGGP +EGMTSFMRSIGDNVFRLDRWELELNSAIPGDDRDTSTPKAVAESMQKLAFGNVLGLTERH +QLMDWFKGNTTGGARIRASVPANWVVGDKTGTCGYGTANDYAVIWPVAHAPIVLAVYTSK +PDRNSKHSDAVIADASRIVLESf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. BvitLS-983 TaxID=1838282 RepID=A0A1C4LGY1_9ACTN +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +QNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_046 TaxID=2175663 RepID=A0A2W0CRR1_9MICO +--AAERAFAALETEHDARLGVVAIDTGSGVGV-AHRADERFAFASAAKVFIAATVLDAAA +--PDDLDAVVPIGQGDVLSYAPVTGQHVGSGMTVRALLAAMVRSSDNTAANLLVARVGGP +AAVQRWLRGIGDDVTRVDRVEPDLNEAVPGDERDTTTPAQFAADLRTVLLGGALDPDDRA +LLVGLMRGTTTGAGTIRAGVPEGWTVADKTGTGSYGVRNDVGIVTPPGRDPIVLVVMTGH +DTADAEPDDALVAAATRTAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseus TaxID=1911 RepID=UPI0008406A1C +--RTRRAFDALEREFDARLGVYALDTGSGRTV-VHRPDERFAYASTCKALLAGAVLERNS +--LRQLDRLVRYGREELISNSPVTERHLATGMTLRELCDAAVRYSDNAAANLLFRELGGP +GGLQDALRALGDRVTRCDRYEVALSDGIPGDPRDTSTPRALATDLRAYVLGDTLPAGKRA +VLTDWLKRNTTGDDTIRAGAPGGWQIGDKTGTGGYGTRNDIAVAWPPGGAPITLAVLSDC +GTKDAARDDALLARAARTAF--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=Q6U8D8_BACTU +----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITKKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKKDAEYDDKLIQ---------- +>[subseq from] Beta-lactamase n=1 Tax=Starkeya novella TaxID=921 RepID=A0A2W5M8N1_STANO +---FAETIKALEARSGGRLGVALLEVGGGLRL-AHRGGERFPMCSTFKALLAAAVLARVD +RGEETTDRRIEIPASAILDGSPFSSARAGADASVAELCEASMTLSDNAAANLLLPSVGGP +QGLTRFLRSIDDPVTRLDRIEPALNEAAPGDPRDTTSPAAMAATLATLVFGETLTPFSRG +ALVRWLIDARTGGKRLRAGLPPDWTAGDKTGAGPNGTTNDVAVLWPPAGQPLVLACYLTG +SALDAAGRDAIHADVARAAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces torulosus TaxID=68276 RepID=UPI0006EB5061 +-------LRALEEQYGARLGVYAHNVRTGETI-RHRADTLFPICSLFKTLAAAAVLRDLD +RDGEVLARRIHYTAADLLENSDVTREHLATGMTIAELCDATIRHSDNTAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRITDTTSPRAIGRTYARLVLGDALSRPDRA +LLTHWLLHNQTSSTRLRAGLPSSWAVADKTGGGSYGTNNNVGIAWTEDGTPLVLSLMSRK +FDQDATTENKLIADTAHLL---- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. 69 TaxID=2035202 RepID=A0A2M8X3T4_9BURK +---WGETLAQIERSAQSRLGVAMLDTGSGLAL-GWRQDERFAMASTFKALLAGWMLALVD +QGKERLDARVLYGRDAVVDYSPVSGPRAGDGLTVAELCSATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDGTTRLDRTEPTLNEAAVGDPRDTTTPQAMLQTLQKLVLGDGLTPPSRA +WLQRWLRETSTGDKRLRAGMP-GWKVGDKTGTTNSGTSNDIGVMWPAGGAPVLVTCYLTE +STAKPEQRDAAIAQVARAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Kitasatospora xanthocidica TaxID=83382 RepID=A0A372ZKT7_9ACTN +--AADAAFAELEQRFGARLGVYAVDTGSGREV-VHRTDERFAFASTIKSLAAGALLRKAS +--DADLDKVVPYRQEDVLAWAPITSQHVATGMKLRDLASAAIQYSDNTAANLVFAELGGP +AAVQQSLRDLGDSTTSVDRTEPTLNEATPGDTRDTSTPRVLAADLRRYVLGDVLPEGRRG +LLTDWLVGNTTGGPYIRAGVPADWRIGDKTGNAGYGTRNDVAVAWPSGGAPIVIVVLTDR +GKADATSDDALIAQATKTVVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Kiloniella majae TaxID=1938558 RepID=UPI000A278888 +----VETVTGLEESIGGRIGVAVYDLQTGQNW-EYRSDEKFPMSSTFKPFACAALLTQNE +RKGETLERMVSVSKDDLVSYSPVIEKYADGGVSLRKSCEATVSISDNTAGNLVLKEIGGP +EGFTKFMRSIGDNTTRLDRWETELNEAQPDDLRDTTSPKAIATSLQKLLLEDALSPEARI +EITNWMLNDQVADDLFRSRLPKGWKIADKTGAGGFGSRGIIAVIWPPSRKAVVASVYMTG +NDADFKTRNAAIAEIGAAIFE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SUN51 TaxID=1828112 RepID=A0A5B0AQM4_9ACTN +--SVTRALTELERAHGARLGVYARNTATGETV-RHRAEETFPMCSVFKTLAAAAVLRDLD +RRGEFLDLRIRYTAQDLTDGSPVTGDNLAHGMTVSALCHAAIAHSDNAAANLLLRELGGP +TAVTRFCRSVGDPTTRLDRWEPELNSAEPWRTTDVTSPAAIGRTYGRLVLGDALVPRDRR +QLTEWLLANTTSTARFRKGLPADWALGDKTGTGSYGTSNDVGVAWTPDGAPVVLAVLSTK +PDPDAPKDDELVARAAELLA--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas guangdongensis TaxID=1141890 RepID=A0A285QXF5_9SPHN +---FAATLADIDRRAPGRLGVAVLDFATGQRF-ALRGGERFPMCSTFKFPLSAAVLHAAD +RGRLPLDRAVAVRRGDIIANSPVTARRVGGSMRVAALCHATMTTSDNAAANLLLPLIGGA +DGFNAFLRAAGDRVTRLDRIEPHLNEGTPGDPRDTTTPAAMLATMRATLFGSVLSAASRQ +RLIGWLVANTTGGRRLRAGLPAGWRVGDKTGTGET-SANDIGVLWPPGRAPILVASYLTE +ARGSQVRRYAVHAEVARAIA--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus sp. RU2C TaxID=1907304 RepID=A0A1N7AU03_9BACI +--TIERKLAKLEDTYDAKLGVYALDTGTNKVI-SYRPDERFGYASTHKALAVGVLLQQKD +--IKDLDKRITYTRDDLVNYNPVTEKYVDAGMTLKELSDASLRYSDNTAGNLILEEIGGP +IGFKKALRELGDNVTNPVRMEPELNDVPPGEIADTSTAKALATSLQAFTLGDALPVEKRE +LLIDWMKRNTTGDALIRSGVPKNWEVADKTGAGLYGTRNDIAVIWPKKGDPIVLAVLSSR +NEKDASYDDKLIAEATKEVVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus salarius TaxID=284579 RepID=A0A428MRM1_9BACI +--NTDEKFAQLENDFDAQIGVYAIDTGSNQTI-EYRPEERFAFTSTYKALAAAIVLKQNS +--MEELKEVITYTEDDLVSYSPVTKNHVDTGMTLLELSEAAVRSSDNTAGNFLFKKLGGP +DEFEQALRQIDDNVTQADRYEPDLNEFTPGDTLDTSTPIALANNLQAFAVGDLLSDEKRE +LFTDWLQGNATGDTLIRAGAPEGWNVGDKSGAGSYGTRNDIAVVRPPNREPIVIAIMSRH +DTEDAKYDDKLIAQVAEET---- +>[subseq from] Class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_008 TaxID=2175656 RepID=A0A2W1V286_9MICO +--AAERAFAALETEHDARLGVVAIDTGSGVGV-AHRADERFAFASAAKVFIAATVLDAAA +--PDDLDAVVPIGQGDVLSYAPVTGQHVGSGMTVRALLAAMVRSSDNTAANLLVARVGGP +AAVQRWLRGIGDDVTRVDRVEPDLNEAVPGDERDTTTPAQFAADLRTVLLGGALDPDDRA +LLVDLMRGTTTGAGTIRAGVPEEWTVADKTGTGSYGVRNDVGIVTPPGRDPIVLVVMTGH +DTADAEPDDALVAAATRTAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium TaxID=1763 RepID=UPI0007EF558C +--DLTSRFTEIERRYQGRLGVYVPASGATPAI-AYRAEERFALCSTFKAPLVAAVLHQYP +--LSYLDQRVTFSKADISSPSPIAEQHVDTGMTVGEMCDAAIRYSDNTAANLLLNRIGGP +AGFTAYLRSLGDSTSRLDHAEPELNRDPPGDERDTTTPHAIAVTMQQLVLGDALPQDKRA +MLTDWMARNTTGGKRIRAAFPADWKVSDKTGSGDYGRANDVAVVWSPAGTPHVIAIYTDI +AGYDAQPNEAFVADAARIVAS-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. OK095 TaxID=1882760 RepID=A0A1H8BKX4_9BRAD +------ELESYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLASMIPYGKADLLEYAPVAKQNLSAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTISRLDHNEPELNRSPPGDPHDTATPAAMASNLKRLVTGEALSGASRA +QLTEWMVGCKTGANRLRGGLPAAWTIGDKTGNNGKDASGDIAVVWPKPDRPILIAAYTQG +GTPTSAQIEAAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis mediterranei (strain U-32) TaxID=749927 RepID=A0A0H3DBE3_AMYMU +-----PDFAPLERSFDARLGVYALDTGSGREI-THRADERFGYASTHKVFSAGAVLRRTS +--LDGLAKNLTYTRADLQPNSPVTEKHVTTGLSLREAMDATLRYSDNTAANLLFRELGGP +AGLAAALREIGDTTTHADRIEPGLNDLAPGDVRDTSTPRAMAGSLRAFALGPALPPEKQT +VLTDMMRANTTGAALIRAGAPAGWAVADKTGSGSYATRNDIAVVWPPGRAPIVLIVMSSR +QAESADHDDRLIAQAAKLALDAf +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium stylosanthis TaxID=1803665 RepID=A0A560EC01_9BRAD +------ELETYERESGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGQADLLDYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDATSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVTGEALSQASRV +QLTDWMVNCKTGANRLRGGLPSSWTIGDKTGNNGKDASGDIAVVWPKPDAPILITAYTQG +GSPTAPQIEAAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium canariense TaxID=255045 RepID=A0A1X3FMV4_9BRAD +--DAQPELETYERESGGRIGVYAENLATGARL-AWRADERFVMCSTFKASLAACVLARVD +RGEDQLAAMIPYGKADLLEYAPVAKQNIAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLRRLLTGEALSATSRA +QLTEWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKDTAPILIATYTQG +GTPSAAQIEAVFARIGRIVAE-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=D6AZL5_9ACTN +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRILYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Kosakonia sacchari TaxID=1158459 RepID=UPI00080751EA +------AVARLEEHLGARIGIAVIDTASGETV-SYRGDERFPLNSTHKALLCGVLLSKVD +KGELALNETTQFSQSELVAYSPVTSKFVAPSMSWQQLCSAAITESDNTAANLLAQKLGGP +AAVTRFFVDSGDSVTRLDRAEPELNSAVPGDVRDTTTPLAVSHTLQKLTLGEVLTPRSRA +QLVQWMKEDKVADALLRSTLPKGWVIGDKTGAGGYGSRSIISIVWPKKGAPRIVSIYITD +TKATIAQSNDAIARIGKAIFS-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TRM49041 TaxID=2603216 RepID=UPI0011F09678 +-----GRLRALERKHDARLGAFAYDTGTGRAV-RYRADELFPMASLFKTLAAAAVLRDLD +RDGEVLAKRVHYTARYVEDYSPVTEQNIANGMTVGELSAAAICRSDNTAANLLLRELGGP +TAVTRFCRSLGDGTTRLDRWEPELNSAEPWRVTDTTSPRAIGRTYARLVLGDALAAHDRE +RLTDWMLANTTSEARFRAGLPEGWLLADKTGGGGYGGNNDVGIAWPPGRPPVVLAVLTTK +FEADAKADNPLVAKAAEILAE-- +>[subseq from] Beta-lactamase n=1 Tax=Marininema mesophilum TaxID=1048340 RepID=A0A1H2S3R5_9BACL +--TITKDFYQLEDKFNAKLGIYALDTGTGQTV-TYRSDERFAYASTHKALAVGALLQQKS +--IKDLDQKITYTRDDLVSNSPITEKHVDTGMTLKELSDASLRYSDNTADNLILKQLGGP +SGFKKSLRKMGDKVTNPKRYEPELNDVKPGEIRDTSTPRALATTLQAFTLGDALPAKKQG +MLVDWMKRNTTGDALIRAGVPDNWEVADKTGGAD-GIRNDIAIIWPPKKDPIVLSILTRS +RDKSSENNDKLIAQATKKVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Lysobacter capsici TaxID=435897 RepID=A0A0S2FW37_9GAMM +---WRTRLRDLEKHSGGRLGVAVLDTGNGERM-LWRENERFRMCSTFKYLLAAAILRQVE +LGKVALSQQVPITAADMISHAPFTQPLVGRSASVAQLCEATVTLSDNPAANLLYPLVGGP +QGLTRFLREIGDGVTRTDRTEPTLNSGAPDDPRDTSTPSAQIATMQRLLLGDALKESSRQ +QLIAWLVANKTGDKRLRAGLPAGVRVGDKTGSGDD-ATNDVAIVWPPGRAPILIVSYLAT +AKLDGAGRDAVLASLARIVSK-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000C15C443 +----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMSVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=unknown TaxID=N/A RepID=UPI00143853E7 +-----------------------LDLNSGKILdSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNR------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces brevispora TaxID=887462 RepID=A0A561TUH3_9ACTN +--RTERAFRELERKFDARLGVYTLDTGSGRTV-THRPDERFAYASTCKALLVGAVLDKNS +--VRQMDRLVRYGREDLVEASPVTERHVATGLTLRELCDAAVRYSDNTAANLLFHELGSP +GALQDALRVLGDNVTRCDRYETALSDATPGDLRDTSTPRALATGLCAYVLGSTLPADKRA +VLADWLRRNTTGDTTIRAGTPDGWQVGDKTGTGGYGTRNDIAVIWPPGAAPITLAVLSRR +RTKDAERDDALIAQAAKVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Marinobacter salarius TaxID=1420917 RepID=UPI000F85468C +---LLEAVKTVEQRLDARVGIALYDSGTGESW-DYHGDDRFPITSTFKTLACAALLAKVD +NGTVDLDRRVIFSKDDLVTYSPVTETRAEEEMSLRELCEATMATSDNTAANLVLGAIDGP +DGVTAYARDLGDTVTRLDRTETSLNEATPGDLRDTTSPKAMVANLRKLVLGEALSKGSRD +TLVTWLKGNRVSDNLLRAAIPPDWTIGDRSGAGGHGSRSITAVLWPPHRPPLVIAIYITQ +TGASFDERNGAIRDLGGAIVKHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB73_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVMLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI0004C7C983 +-----PRLAALERKYDARLGVYALATGTGATV-THRADERFAFCSTFKGMAAAAVLHRHP +--LSYVSTVVTYTEADLMKHSPVTRKHVATGMTIRQLCDAAVRFSDGTAGNLLLREIGGP +GALTAFTRSLGDTVTRMDRIEPAITEATPGDPRDTTSPRAFGTDYRKVVLGNVLAADKRA +FLRDLLERNTTGAERIRAAVPRGWTVADKTGTGDYGTLNDIAVVWPAKSPPLLISIMSSK +STKDAAYDQALIADAAAYVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Inquilinus limosus MP06 TaxID=1398085 RepID=A0A0A0DBY2_9PROT +---AAARLAELERAHGGRLGVAALNLATGARI-GYRADERFLLCSTFKALAAAFVLARVD +RKQERLDRRIAFSRKDIVAVSDVTKPRVGGAMTVAELCDAAVTHSDNTAGNLLLASFGGP +AGLTAFLRSLGDEASRLDRIEPELNAAGPGDPRDTTTPAAVLETLRKLLFGDALSAASRH +RLAAWLITNKTGDARLRAGFPAGWLVGDKTGTGGEGSTNDIAVAWPVDRGPVLVAAYCEL +PSLTFEQRNPVVAEIGGIVA--- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Rhizobiales (miscellaneous) TaxID=41292 RepID=A0A259CD15_9RHIZ +------AFAPLEAKTGGRLGICVLDGAGGIIA-AHRAQERFAMCSTFKLLLAAAVLARVD +EGRERLDRRITYTAADPVGHSPVTRQNVAEGMTVGELCAATVALSDNGAANLLLATLGGP +EGLTAFLRRTGDTVTRLDRWELALNSAIPGDPRDTSTPAAMAGSIRRLVAGTVLKPASRT +QLRDWLVATKTGDTRLRAGLP-GWHVGDKTGTGNNGTVNDVGFALAPGADPVVMVVFLTK +SRLDVEASSGIIADVARQVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02056 TaxID=1703924 RepID=A0A1Q4VIF0_9ACTN +--AADAAFAELEQRFGARLGVYAVDTGSGREV-VHRTDERFAFASTIKSLAAGALLRKAS +--DADLDKVVPYRQEDVLAWAPITSQHVATGMKLRDLASAAIQYSDNTAANLVFAELGGP +AAVQQSLRDLGDSTTSVDRTEPTLNEATPGDTRDTSTPRVLAADLRRYVLGDILPEGRRG +LLTDWLVGNTTGGPYIRAGVPADWRIGDKTGNAGYGTRNDVAVAWPSGGAPIVIVVLTDR +GKADATSDDALIAQATKTVVS-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI0010202172 +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +QNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALDPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas terrae TaxID=405446 RepID=A0A0R0CLX2_9GAMM +------DFAALEKASGGRLGVCLWHPASGARY-GHRMDERFPMCSTVKFPLAAAILHRVD +AGKLSLDQRVAVRQGDIISHSPFTGRHVGKDMTVRDLCRATLIISDNAAANLLLPLIGGP +AGLTAFLREHGDRITVSARNEPELNRFAPGDPRDTTSPAAMAGNLQRFLLGDVLSPASRQ +QLADWLIDNQTGDARLRAGLPQGWRVGDKTGSNGQDTSNDIAVLWPLGGPAWLLSCYLQG +SALDDDGRDGILRQVGELA---- +>[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus poinarii G6 TaxID=1354304 RepID=A0A068R5F7_9GAMM +--EIIHQLSNLEKESNGRLGVVLIDTSDHSTI-TYRANERFPLCSTSKLMAVSALLKKSE +TNAHLLNQRVHYQQSDLIEYSPVTEKHLKDGMTFGELSAATLQYSDNTAMNLLLNQLNGP +HEVTKFARTIGDNHFRLDRPEPALNSAVPGDKRDTSTPQAMADSLYHLALGHALATTQRE +QLTVWLKGNTTGNTSIRAGVPNDWLVGDKTGRCDYGTTNDIAVIWPTKRTPLVLATYFTQ +PEKEAHPRPDVLAAAARIVTQ-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces sp. B29(2018) TaxID=2485016 RepID=UPI000FD68236 +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces fradiae TaxID=1906 RepID=Q59911_STRFR +--RVEGRLRALERTHDARLGAFAYDTGTGRTV-AYRADERFPIASMFKTIAVAAVLRDLD +RDGEVLARRVHYTADYVKRYSPVTGENVANGMTVAELCEATLTRSDNTAANLLLHDLGGP +TAVTRFCRSVGDHVTRLDRWEPELNSAEPGRVTDTTSPRAIGRTYGRLILGDLLAAHDRE +RLTRWMLDNRTSDERFRKGLPADWLLADKTGGGDYGTNNDAGVAWPPGRPPVVLAVQTTR +FTPDAEADNVLVAEAARLLAE-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI00056D90F3 +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ScaeMP-e48 TaxID=1100823 RepID=UPI000823951D +---TDRAFAGLERKFDARLGVYAVDTGDGRIV-AHRPDERFAYASTCKALLAGAVLAKRS +--LPQMERLVRYGEEEIISNSPITEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP +RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYVLGSALPAEKRA +VLADWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVRPPGGAPIALAVLSRR +DTKDAEPQDALIAGAAKVALEAf +>[subseq from] Beta-lactamase L2 n=2 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=A0A0K2ZFA9_XANCT +-qTLAQRLAGIERRTRGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFVLTAAVLQRVD +RGELSLQQRLPIRAADMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP +PGLTRFLRTLGDAQTRSDRHEPEMNRFAADDPRDTTTPAAMAATLRTLLLGDALQPASRQ +QLSAWMLDNRTGDACLRAGLPPGWKIGDKTGSNGTDTRNDIAIVWPPGRMPLLLTAYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces sp. GF20 TaxID=2692235 RepID=UPI001317D684 +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Terribacillus sp. 7520-G TaxID=2025389 RepID=A0A268BQQ5_9BACI +--DAQEPFADLEKAYDAHLGVYAIDTGSGKTA-AYRENERFGFASTHKALSAAVLLQQNS +--LKDLDKKIMYTRDDLVNYNPITEKHIDSGMTLKELGEASVSYSDNTAANLIFEEIGGP +DGLKQALRDIGDQVTEPSRIEPELNNVKPGETQDTSTPKALAESLRAFTLGDSLPAEKRQ +LLIDWLKGNTTGDALIKAGVPEEWEVGDKTGAGAYGTRNDIAVLWPPDSDPIIMAVMSSR +DEADAKYDDALIAKAAEEAV--- +>[subseq from] Beta-lactamase n=2 Tax=Actinopolyspora sp. DSM 45965 TaxID=2586995 RepID=A0A543JXJ3_9ACTN +--EVGERFDRLEQRFDARLGVYAVDTATGEEV-THRADERFAYASTHKALSAGVVLRRNS +--IGGLNRRIHYSASDLVTYSPITKEHVDTGMTLRGVMDAAIRYSDNTAANLLFRELGGP +AALQDALRGIGDTTIHVDRVEPELNRTSPGDIRDTSTARAMAESLRKFTTGDVLSADKRA +ILNEMLRTAKLTGDLIRAGVPSDWEVGDKSGAADYGTRNDVAVIRPPGRAPIMLAVMSDR +QDEDADYDDALIAQAARHVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Methyloceanibacter methanicus TaxID=1774968 RepID=A0A1E3VWZ2_9RHIZ +--ALTRRFSEIETAVGGRLGVAVSDPGTGLAA-ELHGDERFPMCSTFKLLAVAAVLNRVD +KGEETLSREVPVPKSAILSYAPVTEKHAGGVLSLSDLCAAAMVWSDNTAANLVLETVGGP +EAATAYVRSLGDDVTRMDRMEPALNDVGPGEVRDTTTPNAMLGNLDKLFVGDALSPLSRD +LLTEWFVGCKTGTARLRAGLPETWRVGDRTGTGPHGTSNDVAVAWPTGPDPILIAAFLTG +SKADETERDAALADVGEAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Shinella sp. HZN7 TaxID=879274 RepID=A0A1A9FXK1_9RHIZ +----AQRLAALEARHGGRIGVAILNLATGARL-GHNTEERFLMCSTFKALLAGHILARVD +RGEETLDRRIVVKEADLVDWSPVVEKRVGGEISIAELCEATITLSDNAAANLLLAASGGP +KAVTAFLRGFGDTVTRLDRTEPTLNYEAPDDERDTTTPTAMVETLRRLLFAEVLSARSKA +QLAAWLVMNKTGDTRLRAGFPPGWMTGDKTGTNGAGNANDVAVAWSPDRGAVIVAAFCEI +PGISGDARNAVIAEIGRIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. I6 TaxID=2483113 RepID=A0A3N0D6Y3_9ACTN +-----RGLAALERTYSARLGVFARNTRTGRTV-SHRAGELFPMCSVFKTLAVAAVLRDLD +RRGEFLTRRIHYTEKDTEEYAVITQENLANGMTVAGLCDAAIRYSDNAAANLLLRELGGP +SAVTRFCRSLGDGVTRLDRWEPRLNSAEPWRVEDTTSPRHIARTYSRLVLGDALSRPDRQ +RLTGWLLNNTTGKERLRAGLPGDWTLADKTGAGEYGTNNDVGIAWTPDGSPVVLAVLTTR +RHPDAAPDNQLVARTAELLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium oryzae CBMB20 TaxID=693986 RepID=A0A089NX68_9RHIZ +----EPDWGALEHRLDGRLGIAAA-TADRVLA-AYRADARFPMCSTFKVLAAAAVLARVD +TGRETLDRIVAYGSGDLLSYAPVTRKALEAGMTVSDLCAAAIVWSDNSAANLLLASLGGP +EALTAWLRDTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRASLGRILLGTVLSPASRG +RLEAWMIACETGRKRLRAGLPPDWIVGDKTGSGDNGSVNDIAILRPPGRAPVVVAVYVTG +STASAETYAAAYAEIGRLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. B006 TaxID=2201999 RepID=A0A385B1X4_9ACTN +-----AELAALERRFGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS +--DADRDRVLRYRRADLVAHSPVTERHVDTGITLRDAAEAAVRHSDNTAGNLLFDALGGP +AGFARALRDVGDRVTRPVRTEPELNAATPGDTRDTSTPRALVGSLRAYTLGEALPPADRD +LLLGWMRASTTGSALVRAGTLAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVLTSH +DSRGAKPDDALVAQAARATV--- +>[subseq from] Beta-lactamase n=1 Tax=Shinella granuli TaxID=323621 RepID=A0A4R2D1R2_9RHIZ +----AQRLAALEARHGGRIGVAILNLATGARL-GHNTEERFLMCSTFKALLAGHILARVD +RGEETLDRRIVVKEADLVDWSPVVEKRVGGEISIAELCEATITLSDNAAANLLLAASGGP +KAVTAFLRGFGDTVTRLDRTEPTLNYEAPDDERDTTTPTAMVETLRRLLFAEVLSARSKA +QLAAWLVMNKTGDTRLRAGFPAGWMTGDKTGTNGAGNANDVAVAWSPDRGAVIVAAFCEI +PGISGDARNAVIAEIGRIAAE-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI0004BF302D +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus group TaxID=1477431 RepID=UPI000833D88E +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus beddingii TaxID=40578 RepID=A0A1Y2SMB6_9GAMM +-nQLTHQLSMLEKNAGGRLGVVLIDTFDHSTT-VYRANERFPLCSTSKLMAVSALLKQSE +TSGHLLSQRIHYQSSDLTEYSPITEKHLKDGMTLGELSAATLQYSDNAAMNLLLNQLGGP +HEVTKFARTIGDHHFRLDRKEPELNTAIPGDERDTSTPQSMANSLYHLALGNILATIQRE +QLVGWLKGNTTGGASIRAGVPKDWVVGDKTGRCNYGTTNDIAVIWPTNRSPWVLVTYFTQ +PNQNASARPDVLAEAARIMIQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. CT2-14 TaxID=2675850 RepID=UPI0012B96731 +-----AALRALEQQHGARVGVVAIDTGTGKTL-GYRQDERFAFDSTFKPLACGALLHAHP +LNSGFFDQVIHFGADKLVPNSPITSTRLDTGMSVAELCEAAITRSDNTAGNQILELLGGP +QAVTAFLRSIGDRTTRMDRWETELNTNIPGDERDTSTPAVLADDYRKLVLGDTLPEPERT +QLTTWLLANTTGDARIRAGLPADWKTADKTGSGDYGTANDIAVTWPASGAPLVIVVLTTK +PDQAAPADNPLVAALAKEAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Xenorhabdus sp. KK7.4 TaxID=1851572 RepID=A0A2D0JZQ5_9GAMM +--QIIKQLTTLEQSANGHLGVVLINSADNSTI-GYRTNERFPLCSTSKFMAVSALLKKSE +TDENLLKQRVNYKQSDLVEYSPITEKYIETGMTLAELSAATLQYSDNTAMNLIINQLGSP +ESVTTFARTLGDTMFRLDRKEPELNLVQPGDKRDTSTPQAMAESLYKLTLGDSLAPKQRT +QLVEWLKGNTTGNASIRAGLPKDWVVGDKTGRCDYGSTNDIAVIWPSNRAPLVLVTYFTQ +PGKNAKARPDVLAEAARIIIQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=UPI0004919318 +-----RDFAALEAASGGRLGVSLLDTASGQAR-GHRQDERFPMCSTFKALLSAAVLAGAD +RGRWSLDRRLAVGEGDLVPHSPVARRHVGKDLTVRDLCRATMTTSDNAAANLLFGLIGGP +SALTAFLRANGDTVTRNDRLEPVMNAFAPGDPRDTTSPRAMAASMARFAVGDALAAQSRR +QLADWLIDNGTGDACLRAGLGPGWRVGDKTGSNGVDTRNDVAVLWPRDGTPWVLAAYLQG +ATVDSDARDAVLARVARLA---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L4FMQ3_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTD-VTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATM------------------ +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces cavernae TaxID=2259034 RepID=UPI000FEBACA1 +---TSRKWAALERQHSARLGVFALDTATGATV-RHRAGELFPVCSVAKTVAVGAVLRDLD +RDGEFLARRIRYTAADVENHAPITGEHIADGMTVAELCAAAITHSDNAAMNLLLRELGGP +TEVTRFCRSIGDPTTRLDRYEPDLNSAEPWRVADTTSPLAIARTYARLTLGDALEPKDRA +QLTGWLLANTTGANRLRAGLPADWTLAEKTGTGDYGSTHDVGIAWPPHRAPIVLAVLSTK +ADAEAPADEPLLAEAAGLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia exalbida TaxID=290231 RepID=UPI0009FBD38E +------SFAEMETTHSARLGVYAIDTGTGRTV-VHRDGERFPIASTFKGLACGALLREHP +LATGYFDQVIHYSRPELVANSPVTEKHVDTGMTVAELCDATITLSDNTAGNQLLKLLGGP +EGFTAFLRSIGDTASRLDRWEPELNTAVPGDERDTTTAAALATDYRNLVLGDILAEPERA +RLKSWLVAAKTGGARIRAAVPADWTVGDKTGSPAYGGALDVAIAWPPGRAPLVIAVLSTK +FEQNAEADNSLVAEAARAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus TaxID=44249 RepID=UPI0007AC008A +-----VVFKQLETKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS +--NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP +EGFEKAMRDNGNTVVMANRYETELNEAIPGDLRDTSTPNALANSFKVLTIDDSMPNDKQE +LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR +DTEDAEYNNTLVAEAAKAAFK-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00066DA740 +----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAINYEQRASVLAHVGRIA---- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium tropici TaxID=398 RepID=A0A5B0W2Q0_RHITR +----EARLAAIESKHPGRICVSILDMASGKHI-EHRAGERILMCSTFKALAAALVLARVD +KGEEKLDRRIRYSEGDIIGGSPATKLHVGDGMTVAELCAAAVTLSDNAAANLLLASFGGP +KALTAFCRSLGDEITRLDRIEPALNYDAPDDQRDTTTAAAMLENLRRLLFTDVLSAASRS +QLAAWLITNKTGDARLRAGVPRDWLVGDKTGTNGAGNANDIAVLWPSNRAPIIVTAYCEV +PSISADERNAVIAEIGRIAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBV6_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPITRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CB02056 TaxID=1703924 RepID=UPI0009A25617 +--AADAAFAELEQRFGARLGVYAVDTGSGREV-VHRTDERFAFASTIKSLAAGALLRKAS +--DADLDKVVPYRQEDVLAWAPITSQHVATGMKLRDLASAAIQYSDNTAANLVFAELGGP +AAVQQSLRDLGDSTTSVDRTEPTLNEATPGDTRDTSTPRVLAADLRRYVLGDILPEGRRG +LLTDWLVGNTTGGPYIRAGVPADWRIGDKTGNAGYGTRNDVAVAWPSGGAPIVIVVLTDR +GKADATSDDALIAQATKTVVS-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=A0A1B2N773_9GAMM +-----ADFAALEKASGGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKFALSATVLHLAD +QGTLSLDRRLPVRQQDMLSHAPVTKRHVGKDLTVRDLCRATMVTSDNPAANLLLGVVGGP +AGVTAFLRANGDAVTRNDRLEPDMNRFAPDDPRDTTSPAAMAASLQRFVLGEVLTPASRL +QLADWLIDNETGDTRLRAGLSPAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLASYLQG +ATVDDAGRNDTLRQVAVIA---- +>[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. B2-3-3 TaxID=2589960 RepID=A0A504D5A6_9RHIZ +------AFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGMHT +--LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP +RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEKRA +VLTDWLRRNTTGDALIRAGTPASWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR +ATRGAKPQDALIARAARVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. BK340 TaxID=2572903 RepID=A0A559U8Y5_9ACTN +----HTELSDLERRYGARLGVFARNVRTGRTV-AYRAGERFAMCSTFKAFAAAAVLRDRG +-GCAPLDKVINYPPSDILPNSPRTEEHLATGMRVGDLCAAAIQYSDNAAGNLLLRQIGGP +AGLTRFFRSLGDRVSRLDRWETDLNTAIPGDLRDTTTPEAVGRSFERLTLGRALDGAGRE +QLVTWLKGNTTSARRFGAGLPRGWVLGDKTGTGDYATANDIGVAWTTRGTPVVLAVLSTK +AEKDAPVDEALVADTARVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Cra20 TaxID=1327635 RepID=A0A2K8MFL2_9SPHN +--DFRKAVRAVEQTSGGRLGLSVIDLASGERF-GWRASGRFPMCSTFKFALAAAILKQVE +HKHENLNRRISVVAGDIVSLSPFCEQRVGTTASVRELCHATITLSDNSAANLLLRTIGGP +EGFTRRLRAFGDPATRLDRWETAMGEARPGDVRDTTTPEAMADLARQLVLGRALAPASRA +QLVAWMKDTRTSAKSLRAGLPADWTVADKTGAGGFGTDNLVGIVWPPHRAPLVVASYITG +STLEFEQRRPLHAGIGRALA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=A0A264Z2G6_9BACI +--TIERKLAKLEDTYDAKLGVYALDTGTNKVI-SYRPDERFGYASTHKALAVGVLLQQKD +--IKDLDKRITYTRDDLVNYNPITEKYVDAGMTLKELSDASLRYSDNTAGNLILEEIGGP +IGFKKALRELGDDVTNPVRIEPELNDVQPGEIADTSTAKALATSLQAFTLGDALPVEKRE +LLIDWMKRNTTGDALIRSGVPKNWEVADKTGAGLYGTRNDIAVIWPKKGDPIVLAVLSSR +NEKDASYDDKLIAEATKEVVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. EKM101V TaxID=1683695 RepID=UPI00142E4350 +-qSLNNQFEKLERQSGGRLGLAVIDTSDSVQY-SWRGNERFPLCSTSKVMAVAAILKKSE +NADTLLNKKIYISQHDMVNYNPVTMKHIGSAMSLAELSAAALQYSDNAAMNKLLAYLGGP +QYATQFARTLGDTMFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNKLVLGPALKDDQKA +TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPLVLTTYFTQ +HDKSAAARKDVLASAARVIAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759945F +---ALDSIRSIEMSRGGRLGVAVLDTGSGRRL-RYRADESFAMCSTHKFLSAVAVLSLVD +QGKLALDKPVKYGKADLLDYAPVARERVGRGMTIDELCAAATVWSDNTAANLLIELLGGP +AGWTRFARSIGDNASRLDRTEPALNSAIPGDPRDTTTPDAMLANLQQTLLGTVLSDSSRG +RLQNWMLSGTITDTLLRAGVPLTWRVGDKSGAGRNGTRNDIGIIFPPHASPILAAIYYTE +STGSLASREEVIAEVGGIIAKTf +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia brasiliensis TaxID=37326 RepID=UPI00142869CF +----AAELSALEQQYGAQVGLFAVDTGSGKTV-TNRADQRFPFLSTFKGLAAAALLKAHP +LDTGYFDRVIHYTEANLVDYSPVTGAKVAEGMTIAQIADAAITQSDNTAGNLLLRELGGP +QGLTDFLRTIGDQVGRLDRWEPDLNTAYPDDERDTTTPAALAAAYRALVVGDALGAPERD +QLTKWLKANTTGDKRIRAGLPAGWSTGDKTGTGSYGMANDVAVTWPENQSPIVIAIQTRK +PTETADPSNDLVAATTKLALTH- +>[subseq from] class A beta-lactamase n=1 Tax=Labrenzia sp. DG1229 TaxID=681847 RepID=UPI0012EB3538 +---VAKAIEDIETRLSARVGVSIIDTESGKTW-SHKGNERFPMNSTFKAFLCAALLDAAS +NRTVDAGREVVVEESDIVSYSPVTAKRVGGAFTIEDLCRVTVTISDNAAANIVMKEVGGP +EGVTAYLRGIGDDMSRVDRWEPESNTGIPGDDRDTTTPDAAAETLRKLVLDETLAADARA +KLTGWLEGNKVGNSTLRAGLPEGWRIADKTGAGANGSRNNIAVIWPEGRKPLVIAIYITQ +TTAAFEARNKAIAGIAQAL---- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. ACS1 TaxID=2028570 RepID=A0A2A3F764_9NOCA +-qSLDAKIEALEAQYATRIGVTAVYPATGAVY-SHRGDERFAMCSTFKAYASAAVLRKIE +DGSTALDKTVVIEPGDLVENSPVTAAAVGTPMTLGQIAEAALTQSDNTAGNYLLREIGGP +QAVTALARDLGDESTRLDRWETELNTAFRGDPRDTTTPTGLARGFRALLLDDALDAASRD +QLLEWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWSPDGSPIVLAVLTDS +LTEDAQGNNQAIADTTAAVIE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria MEX-5 TaxID=396597 RepID=B1T5K0_9BURK +---ALDAIRSLETSHGGRLGVAVFDTGLRRRL-QYRADESFAMCSTHKFLSAVAVLSLAD +QGKLDLDKPVKYGKTDILDYAPVAKKHVDRGMTVDELCAAATVWSDNTAANLLIELLGGP +AGWTRFARSIGDNASRLDRTEPALNSAIPGDPRDTTTPDAMLANLQQTLLGTVLSDSSRE +KLQNWMLSGTITDTLLRAGVPLTWRVGDKSGAGRNGTRNDIGIIFPPNASPILAAIYYTE +STGSLASREEVIAGVGGIIAKTf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseocarneus TaxID=51201 RepID=A0A3L8KF06_9ACTN +-----GRLRELEREHSARLGVFAHDTGTGRTV-LHRADERFPMCSVFKTLAVAAVLRDLD +HNGEFLAKRVRYSADYAKAWDPVTGKNVANGMTVGELCDAAIRFSDNAAANLLLHELHGP +GTVTRFCRSLGDRTTRLDRWEPDLNSAEPWRETDITSPRAIGETYGGLVLGDALDRRDRA +RLTGWLRGNTTGTERLRKGLPADWTVGDKTGAGSYGTNNDVGIAWPPGRAPIVLAVLTTK +HEHDAKGDDPLVAKAAELVAK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2AG32_STRVZ +--ELVARLRELEARHDARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTLAVAAVLRDLD +HDGTFLARRIWYTAADVKRWSPRTEENLARGMTVAELCDATLRFSDNTAANLLLRELGGP +TAVTRFVRSTGDRTTRLDRWEPELNSAEPWRESDTSTPRAIGRTYGRLLLGDALPHRDRE +RLTRWMLANTTSGERFRKGLPADWLLADKTGGGRYGTNNDAGVTWPPGGGPIVLAVMTTR +SLEDAPVVDPLVAEAAALVAA-- +>[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobium TaxID=374 RepID=A0A1Y2JDE4_BRAJP +------ELESYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARAD +RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVVGEALSPASRT +QLTEWMVGCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPKNKVPILIAAYTQG +GRPNAAQIEAVFARVGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Sporosarcina koreensis TaxID=334735 RepID=UPI0009E7C56B +---IDEKFSQLENEFDAQIGVYAIDTGSNETI-EYKPEERFAFASTYKALAAAILLQQNS +--LEDLKEVITYTEEDLVTYSPITEKHVDTGMTLLELSEAAVRFSDNTAGNLLFEALEGP +KGFEQALREIGDNVTIADRFEPDLNNFTPEDSRDTSTPKALATSLQAFAVSDLLSDDKRE +MFTDWLKGNATGDKLIRAGAPKGWEVGDKSGAGAYGTRNDIAVVWPPDRAPIVIAILSKH +NTVDAKYDDKLISRTAEIALN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. IgraMP-1 TaxID=1839767 RepID=A0A1C4I800_9ACTN +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus koreensis TaxID=99653 RepID=A0A1H5CIC6_9NOCA +-qSLDAKIEALEAQYATRIGVTAVYPATGAVY-SHRGDERFAMCSTFKAYASAAVLRKIE +DGSTALDKTVVIEPGDLVENSPVTTAAVGTPMTLGQIAEAALTQSDNTAGNYLLREIGGP +QAVTALARDLGDESTRLDRWETELNTAFRGDPRDTTTPTGLARGFRALLLDDALDAASRD +QLLEWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWSPDGSPIVLAVLTDS +LTEDAQGNNQAIADTTAAVIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia uniformis TaxID=53432 RepID=UPI00082B21DD +----DTRLTDLERQHDARLGVFAIDTGSGTTV-GTRQDERSPMLSTFKTLACAALLRAHP +LSTGYFDQIIHFTEADAAAYSPVTGKRIDTGMSVLELCDAAITYSDNAAINEVLKLLGGP +QAVTEFARSIGDEVTRLDRWEPELNTAMPGDERDTTTAAAIAGDYQALVLGDALPEPERQ +QLTEWLRANTTGDSRIRAGLPGDWQTGDKTGTSGYGTANDVAVTWPADGAPIVIAVLSTH +ATESADPDDALIAEATKAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Oleisolibacter albus TaxID=2171757 RepID=UPI000DF18CD1 +--AIRSAIADLETRSGGRLGVAVRDMSSGEAV-DWRGEERFPLCSTFKLPATALVLSRVD +RGQERLDRIVPYGTADLIDYSPVTAPHAGTGLSMEALCQGAMILSDNTAANLMLDSFGGP +AALTAFLRDLGDGVTRIDRREPEVNIVPPGEVRDTTSPLAMLHTLERLTLGDSLSPTSRA +RLVGWLIDNRTGDKRLRAGLPAGWRAGDKTGSWDKGTANDVAILWPPGGGPLLVTAYLTE +APGGNDGRNRILAAVGRLVAGG- +>[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas suwonensis (strain 11-1) TaxID=743721 RepID=E6WQI7_PSEUU +---AAADFATLEAAAQGRLGVAVLDAGSGRHLgGHRPEERFPMCSTFKAMLSAAVLAQAD +RGALSLDERLPVGEADIVSHSPVTRRHVGKDVTVRDLCRATMTTSDNGAANLLLGRIGGT +AGLTAFLRGIGDRVTRSDRMEPEMNAFAPGDPRDTTSPRAMAGSLARCVLGDVLSPASRM +QLADWLVDNGTGDDCLRAGIGPGWRVGDKTGGDGAGTRNDIAVAWPLQGSPWVVTAYLQG +AKVDSPSRDAVLARAGALAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia amikacinitolerans TaxID=756689 RepID=UPI000A03AC7E +-----EHLIELERKFDARLGVYALATGTGATV-AHRADERFAFCSTFKGLVAAAVLQRNP +--LSHLDTVVSYTEADLLKNAAVTPKHVDTGMTIRDLCDAAVRFSDGTAGNLLLRDLGGP +AELTAYARSLGDTITRMDRTEPAITQAVPGDLRDTTSPRALGTDYQQIVLGDALPADKRA +FLRDLLERNTTGAQRIRAGVPQGWTVADKTGTGDYGTLNDIGVVWPPNSAPLVLALMSSK +ATPDAPYGQALLAEAAAYVVD-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6D1LSG3_ECOLX +----------------------------NAQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA +QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ +PEQKAESRRDVLAAAAKIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium radiotolerans TaxID=31998 RepID=A0A438LRQ3_9RHIZ +----EPDWTAIERRLGGRLGIAAGS-ADRALA-AYRADARFPMCSTFKVLAVAAVLARVD +AGRETLDRIVTYGPGDLLSYAPVTRKALEAGMSVADLCAATLVWSDNAAANLLLADLGGP +AALTAWLRTTGDPVTRLDRTEPALNTALPGDPRDTTTPDAMRATLGRILLGTTLSPASRD +RLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGDNGTVNDVAILRPPGRAPILVAVYVTG +STASPDACAAAYAEIARLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0012FE3682 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEAVRVGPLHQKQTLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudolabrys sp. FHR47 TaxID=2562284 RepID=UPI0010BF0D0D +----AQRVAALEKKIGGRVGVYLRDITGRVLV-AHRADERFPMCSTFKFLLAAAALKRVD +QGQMSLDQILNFGEADLLSYAPVAKANVAKGLPLAELCAAIVTVSDNTAANVILRNIGGP +QAVTAFARSIGDQDTRLDRNEPDLNSAIPGDPRDTTTPQAIGEDMPRLLSGNALGAASQQ +MLENWMVASKTGLKRVRAGLPNGWVVGDKTGSGANGSANVVAVIRPGNRATLFASVYLTG +SSAPAEELDAVHTEVGRIIAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00039C4D80 +----DREFRRLEKRFDARLGIYAIDTGTGRTV-CYQVDERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKEIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWIVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASSDNALIAQATEVVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. CNPSo 3424 TaxID=2560056 RepID=A0A4Y9LA24_9BRAD +----PAELESYERESGGRVGLHAENLATGAKL-SWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMVPYGKADLLEYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSIGDNTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVVGDALSPASRA +LLTEWMVNCKTGANRLRGGLPASWTIGDKTGNNGKDAAGDIAVVWPKPDTPILIAAYVQG +GAPNAAQIEAAFARIGRTVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CT34 TaxID=1553907 RepID=UPI0005BCB044 +--DTTARFAALEGTYRARLGVYAVATGTGATA-SYRADERFALCSTFKPLAAAAVLHHTP +--SGRLDRRVTYTAADVNSISPITKDHIATGMTLRQLCDAAIRYSDGTAGNLLMRDIGGP +AQLTAYLRQLGDTTSRMDHYEPELNRVRPGDPRDTTTPRAIAADYRELVLGDALTADRRA +LLGDWLERGTTGARRIRAGLPRGWRVADKTGTGDYGRANDIAVVRPPHTSPLVVAIMSDR +AGYSTPPQDALIAATTKLLV--- +>[subseq from] Exo family class A beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A6B1QB46_9ACTN +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALDPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Franconibacter helveticus TaxID=357240 RepID=UPI000DA211EF +--ALTAAAQQEEKTLNARIGVTVLDTATGKTL-SYRGDERFPLNSTHKPLLCGALLKQAQ +EKKIRLTDSVLFDKSQLVDYSPVTEKHVSPQMNWLQLCSAAVSYSDNTAANLISQKAGGP +QAITAFVRASGDNITRLDRFEPELNEARPGDERDTTTPDAISHTLQKLLLGDVLSEASRQ +QLTRWMAEDKVADALLRKSLPKGWKIADKTGAGGYGSRSIISMVWPEKGAPMVVAIYITR +TEASLTQSNDAIARLGGVIF--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SAI-083 TaxID=2485146 RepID=UPI000F514660 +---VAARLRALEERYDARLGVFAHHVPTRRSV-RYRADERFPMCSVFKAVAAAAVLRDLD +RHGEVLARRIHYTEDDLVIGSDRTAEHLAEGMTIAELAEVAITYSDNTAGNLLLRELGGP +TAITRFARSLGDGVTRLDRWEPELNTAEPWRRTDTTSPYAIGRTYGRLVLGDALERRDRE +LLTHWLLSNTTSVNRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTGDGDPIVLSVLSTM +PEPDAVRDDALVADAAAVVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizomicrobium palustre TaxID=189966 RepID=UPI0014223580 +-----AAVTLAEKTSGGRLGVAVIDTGSGARF-SYRGSERFPLCSTFKLLLVTAVLCKVD +AGAESLERRVAVKKGDILGNSPFSAQHVGTSASLGELSEATITLSDNTAANLLLPAVGGP +EGLTKFLAEMGDSVTRIDRYEPIMSSSIAHDLRDTTTPEAMAATVQKFVLGTVLKPASLA +LLQAWLRATKTGSNRLRAGLPADWQVGDKTGTGDHGTSNDVAVIWPPHRAPLVVASYVNE +SKLSDRATQHIHAEVGKAIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium sp. 2SA TaxID=2502198 RepID=UPI0010F86B6F +---ADSAFTQLEDDFDARVGVYAVDLDTGREI-AWRADERFAYASTIKAMASAALLDEVG +--TDGLSKDIAVDEDDIVSHSPVTETNVGGTMTLAELCEAAMTQSDNGAANLIVAELGGP +ASLDSRLDDLGDTGTTVSRTEPDLNEATPGDPRDTTTPRASASNLREYVFGGVLSDDEAT +TLTDWMKATQTGDTLIRADLPEEWTVGDKSGTGSYGSRNDLGIIWPDDGRPIVISVLSSK +KEKDAEADDRLIARAAAAAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Orbus hercynius TaxID=593135 RepID=A0A495RK67_9GAMM +-qATLDKIKAVESQLNTRVGYAELDFNSGLMLeSYRATERFPMMSTFKVLLCGAVLSRVD +SGLEHLDRRIVYHPNDLITYSPVTKDHLSEGMSVAELCSASITMSDNTAANLLLSTIGGP +HALTQFLREMDDPVTRLDRIEPMLNQSLPNDERDTTTPEAMAITLHKLLTGNTLTQTSKQ +QLIDWMVADKVGGPLLRSVLPDGWFIADKTGAGERGSRGIIAVLGPDDKPARIVVIYLTG +SWANMNQLNEQIAAVGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. CBEL-1 TaxID=2502980 RepID=A0A4R4JEG0_9BACI +--TIERKLAKLEDTYDAKLGVYALDTGTNKVI-SYRPDERFGYASTHKALAVGVLLQQKD +--IKDLDKRITYTRDDLVNYNPITEKYVDAGMTLKELSDASLRYSDNTAGNLILEEIGGP +IGFKKALRELGDDVTNPVRIEPELNDVPPGEIADTSTAKALATSLQAFTLGDALPVEKRE +LLIDWMKRNTTGDALIRSGVPKNWEVADKTGAGLYGTRNDIAVIWPKKGDPIVLAVLSSR +NEKDASYDDKLIAEATKEVVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Clostridium estertheticum TaxID=238834 RepID=UPI0013EE68B2 +--QYNSSFSQLESDYGVKLGVYAFDTETHKEV-VYRADDSFAYCSTFKALAAGAVLKQDS +--LEQLKQVVKYNKEDVLSYAPITKDNVDKGMTIEELCNAAVRFSDNTAANLLFDHIGGP +NGFKSSLNQLGDNVTQPTRIEPDLNEAIPEDIRDTSTPRQLATDLQAYTTGDILTDDKKK +ILIDWMTCNATGNTLIRAGAPEGWVVADKSGSGSYGTRNDIAIVMPPNKKPIIIAILSTH +DTKEAKHDDELIAQASKIVFDSf +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. Ag82_O1-15 TaxID=1938855 RepID=A0A2A3JA66_9ACTN +--------RELEARHGARIGAFAYNLRTEATV-RHRAAERFPGCSVFKTLAAAAVLRDLD +QHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRHSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFHAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PARDAAADSPLVAATASVLA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=UPI000BA63791 +-----ADFAALEKASGGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKFALSAAVLHLAD +QGTLSLDRRLPVRQQDMLSHAPVTKRHVGKDLTVRDLCRATMVTSDNPAANLLLGVVGGP +AGVTAFLRANGDAVTRNDRLEPDMNRFAPDDPRDTTSPAAMAASLQRFVLGDVLTPASRL +QLADWLIDNETGDTRLRAGLSSAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ATVDDAGRNDTLRQVAVIA---- +>[subseq from] Beta-lactamase n=2 Tax=Nocardioides sp. AX2bis TaxID=2653157 RepID=A0A653VTI5_9ACTN +--AVRGRLAALEEERDARLGVYAVDTGTGRSV-AYRGGERFAYASTIKALAAGAVLDDLS +--RPELRERVRWTEEDLVEYSPVTELHVEDGLTVRQLIDAAITVSDNTAGNLLFDLVGGP +GALDAALDDVGDRTTEVVRREPDLNTAVPGDPRDTTTPRALATSLGRYVLGDVLPAADRR +LLEATMRRTETGDALIRAGVPQGWRVGDKTGSAGYGTRNDVAVVRPPGGDPVLVAVMTTH +DEADAATDDALVADATRVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderiales bacterium RIFCSPHIGHO2_01_FULL_64_960 TaxID=1797553 RepID=A0A1F4EMP0_9BURK +--EWNETLASIERTAQGRLGVAMLDTGSGLQL-GWRQDERFAMASTFKAVLAGWMLALVD +QGKERLDARVHYAAGDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDSITRLDRTEPTLNEAKVGDPRDTTTPQAMLQTLQKLVLGDVLTPPSRA +WLQRWLVETSTGDKRLRAGVQ-GWKVGDKTGTADSGTANDVAVMWPPGGAPVLVTCYLTR +STVRPEQRDAAIAQVARAVAT-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI000576B0B7 +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWSPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas campaniensis TaxID=213554 RepID=A0A3D0KJP4_9GAMM +--NLLTEVERIEEQLDARVGFAAYDLETGQRW-EYNADQLFAMSSTFKTLACASLLQRVD +EGSEQLERQVKVSASDIVTYSPVTEAYADNRISLFELCEATMTTSDNTAANLILQAIGGP +QAVTAFVRELGDSVTRLDRWETELNEAAPHDERDTSTPNAMVSNLEKLVVGNALSLQSKN +QLREWLVNNEVADGLFRSQMPDEWVIGDRTGAGGFGSRSITAVIWPPERKPTIVAFYITE +TDASFEERNSAIAELGSVI---- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=UPI000B89BDE5 +-----ADFAALEKASGGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKFALSAAVLHLAD +QGTLPLDRRLPVRQQDMLSHAPVTKRHVGKDLTVRDLCRATMVTSDNPAANLLLGVVGGP +AGVTAFLRANGDAVTRNDRLEPDMNRFAPDDPRDTTSPAAMAASLQRFVLGEVLTPASRL +QLADWLIDNETGDTRLRAGLSPAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLASYLQG +ATVDDAGRNDALRQVAVI----- +>[subseq from] Class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_030 TaxID=2175649 RepID=A0A2W0CH86_9MICO +--ATRRAFDGLEGAHDARLGVVAIDTGSGATV-THRAGERFAFASAAKVFIAATVLDDAS +--PADLDAVVPIEQRDLLSYAPVTSQHVGSGMTVRALLDAMLRSSDNTAANLLVARVGGP +SVVQQWLRGIGDQVTQVVRIEPDLNEATPGDDRDTTTPAQFAADLRTVLLGDALQPDDRE +LLVDTMAGTTTGDATIRAGVPTGWTVADKTGTGSHGVRNDVGIVTPPGGAPIVLVVMTSR +STADAEPDDALVAAATRTAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis flavescens TaxID=758803 RepID=A0A1M6JHB5_9ACTN +---LDSDFTRLEEEFDTRLGVYALDTGTGLAI-EFQADERFAYCSTFKVLAFGAVLDRTP +--LDQLDRVVTYSEADLVFHSPVTREHVSTGMTLREIGDAALRHSDNTASNLLFEELGGP +QGLGEALRGIGDDVTRVDRIAPEMAEAVPGDVRDTSTPRAMAASLRAFALGDVLPQEKRD +ILVAMMRANTTGDDLIRAGVPEGWRVGDKTGACGYGTRHDIGVLWPPAGDPVVLAVMSSR +DEAGAGYDDALVAQAAALAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas venusta TaxID=44935 RepID=A0A3Q8WG13_9GAMM +--TLLTEVERIEEQLDARVGFAAYDLETGQRW-EYNADQLFAMSSTFKTLACAALLQRVD +EGSEQLERRVKVSASDIVTYSPVTEAYADNRISLFELCEATLTTSDNTAANLILQAIGGP +QAVTEFVRALGDSVTRLDRWETELNEAAPHDERDTSTPNAMVSNLEKLVVGNALSPQSKN +QLRVWLVNNEVADGLFRSQIPDEWVIGDRTGAGGFGSRSITAVIWPPEREPTIVAFYITE +TDASFEERNSAIAELGSVI---- +>[subseq from] Class A beta-lactamase n=1 Tax=Ideonella dechloratans TaxID=36863 RepID=A0A643FHS3_IDEDE +--ALQQALQDIESRAGGRLGLAVLDTGSGRRW-LHRADERFLLCSTFKLLLCAQVLDRAA +RGEERLDRQLAFRRSDLVEWSPVTKKAVGRGLSVAQLCEATMTTSDNTAALLLLKTQGGP +AGLTRWLRAHGDTQTRLDRSEPDLNLADPTGEWDTTTPAAMADTVQRLCLGAGLPKTVQA +QLQAWMKASTTGAQRLRAGLPTGWQIGDKTGTGD-GISNDVAIVWPPGQAPWVVVAFLSN +CRSPREAQQACLAEVGRLL---- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI0010222E2C +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM1743 TaxID=318996 RepID=UPI000423204A +------ELETYERESGGRIGVYAENLTTGAKL-AWRADERFVMCSTFKASLAACVLGRVD +RGEEQLAAMIPYSQADLLEYAPVARENLAAGMSVGEMCKAIVELSDNTCANLLLTRIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLRRLVTGEALSPASRA +QLTEWMVNCKTGAKRLRGGLPAGWKIGDKTGYNGKDAAGDIAVAWPKPDTPVLITAYVQG +GTPTPAQIAAVFARIGHMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora sp. MY 5-36 TaxID=1678027 RepID=UPI0007C7860C +--AADAAFAELEQRFGARLGVYAVDTGSGREV-VHRTDERFAFASTIKSLAAGALLRKAS +--DADLDKVVPYRQEDVLAWAPITSQHVATGMKLRDLAAAAIQYSDNTAANLVFAELGGP +AAVQQSLRDLGDSTTSVDRTEPTLNEATPGDTRDTSTPRVLAADLHRYVLGDVLPEGRRG +LLTDWLVGNTTGGPYIRAGVPADWRIGDKTGNAGYGTRNDVAVAWPSGGAPIVIVVLTDR +GKADATSDDALIAQATKTVVS-- +>[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2T1IMW5_STEMA +---TANDFAALEMACAGRLGVTLLDTASGRRL-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATVITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPEMNSFAEGDPRDTTTPAAMAATLQRVVLGDVLQPASRQ +QLSDWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA +SAISNEQRAGVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium arachidis TaxID=858423 RepID=A0A1I7FFP1_9BRAD +----PSELESYERESGGRIGLYAENLATGARL-AWRADERFVMCSTFKASLAACVLARVD +RGDEQLAAMIPYGQADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARVGGP +AALTAFWRSLGDATSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLIVGEALSPASRA +QLTEWMVNCKTGANRLRGGLPAGWKIGDKTGNNGRDASGDIAVVWPKNKAPILITAYTQG +GTPNAAQIEAAFARIGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium TaxID=374 RepID=UPI0003F5ADCB +----PSELESYERESGGRIGLYAENLATGARL-AWRADERFVMCSTFKASLAACVLARVD +RGDEQLAAMIPYGQADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARVGGP +AALTAFWRSLGDATSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLIVGEALSPASRA +QLTEWMVNCKTGANRLRGGLPAGWKIGDKTGNNGRDASGDIAVVWPKNKAPILITAYTQG +GTPNAAQIEAAFARIGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0003A4484D +----DREFRRLEMRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDNALIAQATEVVIA-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI0009A112B6 +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK +TEQDAVRDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas sp. SGD-10 TaxID=2493089 RepID=A0A426HGR7_9GAMM +----APDFAALEAASQGRLGVAVLEAGNGRYLaGHRADERFPMCSTFKALLAAAVLARAD +RGALDLDERLPVRAADLVPHAPVTRRHVGKDLGVRDLCRAIVTISDNTAANLLFARIGGP +AALTAFLRGLGDTVTRSDRLEPEMNGFVAGDPRDTTSPRAMATSLGRCVAGAVLAPASRL +QLADWLIDNTTGDDCLRAGIGPEWRVGDRTGSNGTDIRNDVAVLWPLGGSPWVVAAYLEG +SRVDSAARDAVLARAGQLAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium sp. 1M-11 TaxID=1529006 RepID=UPI0006C76E53 +--EAENKLAELERKHPGRFCVTILDLGNGRRI-QHRADERILMCSTFKALLAAFALARVD +KGEEKLDERIKITKKDLVTNSPVTKPHLGGPLTIAELCDAIVTRSDNTAANLLLARFGGP +AALTAFCRRLGDDLTRLDRFELELNHDGPDDQRDTTTAAAMAETLRKLLFSDVLSAASRS +QLAAWLITNKTGDTRLRAGVPGDWLVGDKTGTNGHGNANDIAVIWPPDRAPLIVTAFCEI +PEISSKDRDAVIAEIGRIAS--- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI00101E7A60 +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. CNPSo 3448 TaxID=2560055 RepID=A0A4Y9LWM1_9BRAD +------ELEAYERESGGRIGLYAENLATGAKI-AWRADERFVMCSTFKASLAACVLARVD +RGQEQLAAMIPYGQADLLSYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRIDHNEPEVNRSAPGDPHDTTTPAAMAGNLRRLVTGEALSPASRA +QLTEWMVGCKTGANRLRGGLPASWTIGDKTGNNGEDASGDIAVAWTTPDTPILIAAYTQG +GSPTAPQIEAAFARIGRMVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mixta intestinalis TaxID=1615494 RepID=UPI001367748A +--ALTQQLAALEKSVGGRLGVAWID-EGASHY-GYRADERFPMTSTFKTLAVAAILHQNV +SQPHLLEKKIAIEEADRVPWTPVTGNYFGKKMSVAALCAAAIEYSDNLAANYLLKEAGGP +QGITRYARYLGDSVTQLNRLEPELNSAVPGDKRDTTTPAAMAENLYKLTLGTALPTAQRQ +QLISWLQQSTTGAESIRAGVPAGWRVGDKTGAGAYGSTNDIAILWPEKGAPKILAIYFTQ +PQPDAANNKAVLAAATRLTIK-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI000527D617 +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Izhakiella capsodis TaxID=1367852 RepID=A0A1I4VBV7_9ENTR +--NLHLQLATLEKRYNGRLGMTLLDTASGHKL-QYRGNERFPMCSTSKTLLAAVVLNLSL +QQPGLLERRIYWDTSERLSWMPVTEKHYESGMTVNELCQAMLQYSDNLAANLMLKLVNGP +AAVTTLARSLGDNVTRLDRTEPALNSAIPGDKRDTTTPLAMASDLQKLAFGNGLPHREQQ +LWIRWLKGNTTGKQSIAAGVPAVWKVGDKTGSGDYGTTNDVALLWPPQRQPLVLTVYFTQ +PDKTAASNRTVLAETARLTLATw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB33_STEMA +----ATDFAALEKACGGRLGVSLLDVASGRRA-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFAVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAEGDPRDTTTPAAMAVTLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRAMVLAQVGRIA---- +>[subseq from] Beta-lactamase n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A0S1ULF5_9ACTN +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. 13MFTsu3.1M2 TaxID=1502776 RepID=UPI0008EB7A10 +---AEPDWAAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKALAVAAVLARVD +AGRETLDRVVSYGAGDLLSYAPVTRKALGTGMSVADLCAATLIWSDNTAANLLLADLGGP +EALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMQATLGRVLLGTVLSPASRA +RLEAWMVACETGRKRLRAGLPPGWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTE +STASPDTCAAAYAEIGRLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=[Kitasatospora] papulosa TaxID=1464011 RepID=UPI0004BE3BB8 +------AFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGMHT +--LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP +RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEKRA +VLTDWLRRNTTGDALIRGGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR +ATRGAKPQDALIARAARVAL--- +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB51_STEMA +---AASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGTPWVLTAYLQA +GAISYDQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI000491E178 +----DREFRRLEQRFDARLGIYAIDTGTGRTV-RYQADERFAYASTYKALAAAEVLDETT +--DAELEQVVRYPADDLVDYSPVTEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDEVTDAARYETALNEATPGDRRDTSTARALTEDLRQYAVDDALEPADRD +ILNAWLRGNTTGGALIRAGVPDGWAVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DERGASYDDALIAQATEVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MA5143a TaxID=2083010 RepID=A0A2P9FCX1_9ACTN +----TDGLRALEGQYGARLGVYAHHVRTGKTI-RHRADTLFPICSLFKTLAAAAVLRDLD +RDGEVLSRRIHYTAADLLENSDVTREHLATGMTIAELCDATIRHSDNTAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSGEPWRITDTTSPRAIGRTYARLVLGDALSRPDRA +LLTHWLLHNQTSGTRLRAGLPSSWAVADKTGGGSYGTNNNVGIAWTEDGTPLVLSIMSRK +FDQDATTENKLIADTAHLL---- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. NBS 14/10 TaxID=1945643 RepID=A0A229H1A4_9ACTN +----TREFRDLERKFDARLGVYAIDTGTGEEV-AYHDGERFAYNSTFKAMAAGAALKKYS +--LSGMDRKITYSKDVLIANSPVTEKHVATGMTLGELCDAAVRYSDNAAANLILKELGGP +KALDATLEKLGDDVTRMERPEPYLSEWVPGELRDTTTPRAFAKDLRAFVLGDVLAEGERA +QLTKWLRTNMTGDKVIRAGVPKGWVVGDKTGTGSYGGRNDIAVVWPPDSAPIVIAILSHR +GKKDAEPDDRLIAEAASVIAD-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium cytisi TaxID=515489 RepID=A0A5S4W7X6_9BRAD +------ELESYERESGGRIGVYAENLATGAKL-TWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGKTDLLEYAPVAKQNLPAGMSAADMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSIGDTISRLDHNEPELNRSPPGDPHDTTTPAAMAGNLKRLVTGEALSPASRA +QLTDWMVGCKTGANRLRGGLPAAWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYTQG +GTPNVAQIEAVFARIGRMVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Xylophilus sp. KACC 21265 TaxID=2697032 RepID=UPI00136779B4 +-------LAELESAYGGRLGLALTS--AGRPLlSYRADERFPACSTFKALLAATVLNRAS +SDPGLLGRRVMYGQADLKTYAPVTGRLVDQGMTISHLCAAAVQYSDNVAANLLMREIGGP +AGVTAFARWLRDDSFRLDRWEPELNSAIPGDPRDTCTPRDMARNLHKLVLGQALPARERE +LLKSWLLGNTTGNGRIRASVPENWPVGDKTGTGEYGSTNDIAVIWPADGPPLVLAIYFTQ +FQADAQAREEVIVEATRLAL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Candidatus Competibacteraceae bacterium TaxID=2053538 RepID=A0A3C1STS0_9GAMM +--EAEKELVNLERACRGRLGVHVIDTSTGQRF-GHRSDERFLMLSSFKLLAAGFVLDRHD +RGEDSLDRRIRYTRADLVEWSPVTEKHVGGDLTLAELCHATITTSDNTAANLMHQSYGGP +AALTRFVRRLGDLTTRHDRYEPDLNTSDPNQPSDTTTPRAIAETTGKLVVGDVLSSSSRR +LLQDWLLANTTGGKRLRAGFPLGWRIGEKTGTAPSVGANDVGVAWPPDGAPLLVSAYVET +TSVSQETRDATIATVAKLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Dactylopiibacterium carminicum TaxID=857335 RepID=A0A272ESU5_9RHOO +--DLRALCKRLEQSSGGRLGVYMHDVCRSQEF-LYREDERFAMCSTFKWLLAAAVLGRVD +AGQERLDRRVRFSRRDLLEYSPATTPFADGPMSLAQLCEGAIVDSDNTAANLLLNALGGP +SGFNAFLRMQGDQVTRLDRPEPELNEARAGDPRDTSTPSAMGRDLHRLLLEDRLSAASCR +QLTDWMLATRTSGARLRAGLEEGWRLADKTGSGRNGTANDVGIYWTPAGDPIVLCVFLTG +ARFDGAAQAATIATLGRAV---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces klenkii TaxID=1420899 RepID=A0A3B0AQR1_9ACTN +--RIARRLRELEQEHSARLGVFAHNTATGRTV-AHRADELFPMCSTFKTIAVAAVLRDLD +RDGEFLAERIHYTKKEVEDYDKITGRNVANGMTVEELCAAAISYSDNGAANLLLRELGGP +TAVTRFCRSTGDRITRLDRWEPALNSAEPDRTTDTTTPRAIGRTYARLVLGNVLDPADRK +RLTGWLLANTTSGEKLRKGVPAGWTVADKTGAGSYGTSNDVGVTWTPHGAPVVMSILTTK +HEAGAEGDSPLVAETARLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. K1PN6 TaxID=2596892 RepID=A0A5N8X3W8_9ACTN +-----GELKELEREYDARLGVYAIDTGTGREV-AYRDGERFGYHSTFKALEAGAVLRKYS +--LSGMNRVVRYSEDDLIANSPITEKHVETGMTLSELCDAAVRYSDNAAANLLYEELGGP +KALEAELRKLGDKVTSMDRIEPHLSNWVPGETRDTTTPRAVAKDLRAYVLGDVLGKRERD +RLTTWLKTNTTGDEVIRAGVPEGWVVGDKTGSGSYGARNDIAVVWPPDSAPIVMAILTNR +GKEDDTHDNKLIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI0012962ED6 +-hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD +KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAINLLLESFGGP +PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMEILRKLIFGEVLSRSSRA +QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHANNNDIAVAWSPNRGAIVVATYCEI +STISADERNAVVAEVGRLVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 7504-2 TaxID=2022547 RepID=A0A268IAG9_9BACI +--STTKQFKQLEEEFAARLGVYVIDTETNKTI-NYRADERFAYTSTFKPFAAAFILQKST +--ISELKKLKTFTTNDLVTYSPITEKHVQTGMNLLEISEAAIQYSDNTAGNLLLEELGGP +KGLQQALRKIGDQTTSVDRYETELNEATPGDSRDTSTPKALAKNLQYVGIDEFLSQSKKD +IFQDWLKGNTTGDSLIRAGVPKDWVVGDKSGAGGYGTRNDIAIVWPPERKPIIMVIMSSK +DEVEATYNDELIANTAKVIVETf +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. yr668 TaxID=1761801 RepID=A0A1I6VT36_9RHIZ +---AEPDWAAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKALAVAAVLARVD +AGRETLDRVVSYGAGDLLSYAPVTRKALEAGMSVADLCAATLIWSDNTAANLLLADLGGP +EALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRVLLGTVLSPDSRA +RLEAWMVACETGRKRLRAGLPPDWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTE +STASPDTCAAAHAEIGRLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia lijiangensis TaxID=299618 RepID=UPI00082B3D2B +----HEHLAELERRFDARLGVYALATGTGATI-AHRADERFAFCSTFKGLAAAAVLHRNP +--LSHLDTVVSYTEADLLKSASVTSRHVATGMTIRDLCDAAVRFSDGTAGNLLLHDLGGP +AELTAYTRGLGDTVTRMDRIEPAITEATPGDPRDTTSPRALGTDYQQIVLGDALPADKRA +FLRDLLERNNTGAQRIRAGVPQGWTVADKTGTGDYGTLNDIGIVWPPGSAPLVIALMSSK +ATVDAPYDQALLAQAAAYIVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Acidobacterium sp. S8 TaxID=1641854 RepID=UPI00131E6928 +--SLPESLAKLEKDCEGRLGVAVLDIGSGESS-GYRVDERFAMCSTFKMLLAAAVLQRVD +TGKENLDRMVQMPTTGFLFNSPMTQPHAGGKMAVSDLCVAILTRSDNTGANLLLETIGGP +AGITQFARSLGDNVTRLDRVETALNEALPGDPRDTTSPAAMAANWRKVLLGDKLLTASRK +QLTDWLIANKTGDERLRAGSPTGWTVGDKTGSNGENTTNDVAILWPTAQAPVIVAAYLTS +CAGPESKRDAVLAEVGRQVAK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces misionensis TaxID=67331 RepID=A0A1H4NJ12_9ACTN +-------LGVLERDYGARLGVYARNVRTGRVL-AHRAGERFAHCSVFKAFAAAAVLRDRS +-GCAPLDKVIHYPPHDILPNSPRTEENQETGMTVADLCAAAIQYSDNTAGNLLLQQVGGP +AGLTGFFRSLGDRVSRQDRWEPELNTAIPGDLRDTTTPEAIATSLERLTLGRALPAPDRE +RLVTWMKGNTTSGARFRAGLPEGWTLADKTGTGFYASAHDIGVAWTTRRTPVVLAVLSTK +DEKDAPVDEALIREAARIAAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Marinobacter sp. JB02H27 TaxID=2597703 RepID=UPI00124631C7 +---VVAALDRMAEELDARVGFSAYDLETGQRW-EYQADQRFPLLSTFKTLACAELLYRAD +EGEVPLSREVSFSDPDLLTYSPVTEKFAGRQMTLSELCEATLATSDNTAANLILRALGGP +ESITTFATSLGDDVTRLDRWETELNEAQPGDPRDTTTPNAMVSNIQRLLLGEVLSVASRR +QLRNWLEGNQVADGLFRAAVPEGWVVADRTGAGGFGSRSITAVMWPPERQPIVVALYITE +TESSLSERNEAIAKIGAVIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBA15_005 TaxID=1898734 RepID=UPI0009F4D6B1 +--ATARAFAALERRYDARLGVVAVDTGDGRTI-AHRAGERFAFASTIKVFIAAAVLGASS +--DTDLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTRVDRVEPDLNEATPGDPRDTTTPERFAADLRTVLLGNAIDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSR +ADPGAEPSDALVAAATRAAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Xenorhabdus ehlersii TaxID=290111 RepID=A0A2D0IR12_9GAMM +---IIHQLSILEKNANGRLGVVLIDISDHSTI-TYRANERFPLCSTSKLMAVSAILKKSE +TNIHLLNQPVHYQRSDLVEYSPITEKHLKEGMTLGELSAATLQYSDNTAMNLLLNQLNGP +NEVTHFARTIGDNSFRLDRYEPELNTAIPGDERDTSTPQAMAKSLYNLVLGDALATIQRE +QLAEWIKGNTTGGASIRAGVPKDWIVGDKTGRCDYGTTNDIAVIWPVNRAPLVLVTYFTQ +PDKKASARPDVLAAAARIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax radicis TaxID=758826 RepID=UPI0004980336 +--QWNDTLAGIEHFAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD +QGKERLDARVHYAAADVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDGITRLDRTEPTLNEAKVGDPRDTTTPLAMLQTLQKLVLGDVLTPPSRA +WLQRWLVDTSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVLWPPGGAPVLVTCYLTR +STAKPEQRDAAIAQVARAVAT-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus siralis TaxID=77777 RepID=UPI0010F571C5 +--STTEQFKQLEEEFAARLGVYVIDTETNKTI-NYRADERFAYTSTFKPFAAAFILQKST +--ISELKKLKTFTTNDLVTYSPITEKHVQTGMNLLEISEAAIQYSDNTAGNLLLEELGGP +KGLQQALRKIGDQTTSVDRYETELNEATPGDSRDTSTPKALAKNLQYVGIDEFLSQSKKD +IFQDWLKGNTTGDSLIRAGVPKDWVVGDKSGAGGYGTRNDIAIVWPPERKPIIMVIMSSK +DEVEATYNDELIANTAKVIVETf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCCC3C +----EAQLAALESKHPGRICVSILDMASGKRI-EHRAGERILMCSTFKALAAALVLARVD +KGDEKLDRRIHYKRGDLIDYSPATEPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP +KAVTAFCRSLGDDLTRLDRTEPTLNYDTPDDQRDTTTASAMLENLRRLLFSDVLTPASRS +QLAAWLITNKTGDARLRAGIPKNWLVGDKTGTNGAGNANDIAVLWPASRAPIIVTAYCEI +PEIAADERNAIIAEIGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium huanghuaihaiense TaxID=990078 RepID=A0A562S3H2_9BRAD +------ELETYERDSGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIAYSQADLLDYAPVAKHNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +ATLTAFWRSLGDTTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVTGEALSAASRA +QLTDWMVNCKTGANRLRGGLPADWTIGDKTGNNGKDASGDIAVVWPKNKAPILIAAYTQG +GTPNAAQIAAVFARIGRMVAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P1ZF61_STRVZ +--ELVARLRELEARHDARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTLAVAAVLRDLD +HDGTFLARRIRYTAADVKRWSPRTERNLARGMTVAELCDATLRFSDNTAANLLLRELGGP +TAVTRFVRSTGDRTTRLDRWEPELNSAEPWRESDTSTPRAIGRTYGRLLLGDALPHCDRE +RLTRWMLANTTSVERFRKGLPADWLLADKTGGGRYGTNNDAGVTWPPGGGPIVLAVMTTR +SLEDAPVVDPLVAEAAALVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. KM273126 TaxID=2545247 RepID=A0A4R1DCW8_9ACTN +-----GELKELEREYDARLGVYAIDTGTGREV-AYRDGERFGYHSTFKALEAGAVLRKYS +--LSGMNRVVRYSEDDLIANSPITEKHVETGMTLSELCDAAVRYSDNAAANLLYEELGGP +KALEAELRKLGDKVTSMDRIEPHLSNWVPGETRDTTTPRAVAEDLRAYVLGDVLGKRERD +RLTTWLKTNTTGDEVIRAGVPEGWVVGDKTGSGSYGARNDIAVVWPPDSAPIVMAILTNR +GKEDDTHDNKLIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. FXJ1.172 TaxID=710705 RepID=A0A176KZA6_9ACTN +---AAGELSALERRHGARLGVFARNLRTGRTV-AHRAGERFAMCSTFKAFAAAAVLRDHG +-GCAPLDKVIHFPPHDILSNSPRTAEHVDTGMTVADLCAAAIQYSDNAAGNLLLRQIGGP +AGLTRFFRSLGDEVSRLDRWETDLGSAIPGDLRDTTTPEALGRSFERLTLGRALSGADRA +RLVGWLKGNTTSAARFGAGLPRDWVLADKTGTGDYGTANDTAVAWTTRGTPLLLTVLSAK +SAQDAAADDALVAEAARILAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Gracilibacillus TaxID=74385 RepID=UPI0008271176 +---SEEAYKELEDERDAKLGIYAVDTGTNQTV-AYRADERFAYASTFKVLAAGAILQNTS +--IDDLEKGITYSEEDLVTYSPVTENHVDDGMKLKEVMEAAIRYSDNTAGNLLLKELGGP +DGLEENLREIGDETIEVDRVEPDLNEAVPGDTKDTSTPKAFAESLQKYVLSDLLPEEKRK +LLIDWMTGNEAGDTLIRAGVPEGWKVIDKSGAGGYGTRNDIAVVWPSDHAPIVISIFSSR +DKEEADFDDTVVEKAAELVVEQ- +>[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus jeddahense TaxID=1462527 RepID=UPI000595FFDB +--QSEEAFKELEEEFDARLGVYAIDTETDQTV-SYRSDERFAYASTFKVLAAGAILQIAS +--MDDLEKVITYSEDDLVTYSPVTEEHVDDGMKLKEIMEAAIRYSDNTAGNLLLEELGGP +DGLEEILRENGDEIIEMDRMETDLNEAAPGDTRDTSTPKALAESLQTYVLSDLLPEDKQD +LLIDWITGNEAGDTLIRAGVPEDWEVGDKSGAGGYGTRNDIAVVWPSDQEPIIISVLSSR +DSEDADYDDALIEKAAERVME-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. PRh5 TaxID=1158056 RepID=A0A014LIH0_9ACTN +--AVAGEFKKLERSYDAHLGVYAIDTGTGHEV-AYRDGERFAFASTFKALEAGAVLRKYK +--LSGLDRVIRYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGP +KGLDATLEKLGDDVIQMENIEPELSRWVPGETHDTTTPRAMAKDLRAFVLGDVLGKGERA +QLTKWLRTNTTGDELIRAGMPKGWQVGDKTGSGSYGARNDIAVVWRPGAAPLVMAIMSYR +GDKDTPFDNKLIADAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. RFCAC02 TaxID=2499143 RepID=UPI0010218636 +--DAGRAFTDLEAEYGARLGVYALDTGTGREI-THRAGERFAYASTFKALAAGAVLRAYG +--THGIDRVITYTRDDLLAHAPVTEDFVHTGMSLRDLCAAALRYSDNTAANLLFDALGGP +DGLEAVLRGLGDGVTEVDRVEPDLNEAAPGDTRDTSTPRALAGSLRAFLLGDALAPDERG +LLRHWMTTNTTGGTLIAAGVPDGWTVADKSGSAGYGGRNDIAVVWPDDGAPLVIAVLSGR +DTEDAEPDDALIAGAAALAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0F6QEY8_KLEPN +---LEKRLAELEGRHKGRIGVAIHNLATGARI-GHRADERFLMCSTFKALLAAHILARVD +RKEETLDRRIVVGKSDLVDWSPVVETRVGGEISIAELCEAAITLSDNAAANLLLSASGGP +KAVTQFLRGFGDDVTRLDRTEPTLNRETPDDERDTTTPAAMAETLRKLIIGDVLARGSKA +QLAAWLVMNKTGDTRLRAGFPVDWTTGDKTGTNGHGNANDVAIAWSPDRGAVVVTAFCEI +PGISGDERNAVIAEIGRIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Labrenzia sp. PT13C1 TaxID=2135612 RepID=A0A4R7RVV3_9RHOB +---LAKAAKAIESRLNTRIGVAVFDSASGLNW-NYNGEDRFPMNSTMKAFACAALLDRVD +KKQSSLDQRTIVTSDMIVSYSPVTEKHINTAMTLADHCEATITISDNTSANIILEELGGP +IGVTTFMRSIGDDVTRLDRYEPSLNEGTPGDPRDTTTPVAAAQSLYKVLFSDELSASSRK +HLMEWLEANKVGDATLRAGLPHDWRIGDKTGAGAYGSRGNIAIIWPPNHTPVALAIYVTE +NEVEFQARNKAIAEIGAAFK--- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. SD340 TaxID=1690268 RepID=A0A0N8VUH6_9BURK +--EWNETLANIERTAQGRLGVAMLDTGSGLQL-GWRQDERFAMASTLKAVLAGWMLALVD +QGKERLDARVHYAAGDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDSITRLDRTEPTLNEAKVGDPRDTTTPQAMLQTLQKLVLGDVLTPPSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVLWPTGGAPVLVTCYLTR +STAKPEQRDAAIAQVARAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rhizosphaericus TaxID=114699 RepID=UPI000A3D2E3E +--AVAGEFKKLERSYDAHLGVYAIDTGTGHEV-AYRDGERFAFASTFKALEAGAVLRKYK +--LSGLDRVIRYSKDDLVENSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGP +KGLDATLEKLGDDVIQMENIEPELSRWVPGETHDTTTPRAMAKDLRAFVLGDVLGKGERA +QLTKWLRTNTTGDELIRAGMPKGWQVGDKTGSGSYGARNDIAVVWRPGAAPLVMAIMSYR +GDKDTPFDNKLIADAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium guangdongense TaxID=1325090 RepID=A0A410VFC9_9BRAD +------ELDSYERESGGKIGVYAENLTTAKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEDKLAAMISYDKGDLLEYAPVAKQNLTTGMSVAEMCKAIVELSDNTCANLLLARVGGP +AALTKFWRSIGDTTTRLDHNEPELNRSPPGNPHDTTTPAAMAGNLKRLVIGEVLSPASRA +QLTAWMVDCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAVYTQG +GTPSPAQLEAVFARIGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-3229 TaxID=1463836 RepID=UPI0004BE5954 +--DVAARLRALEQRYDARLGVFAHRLSTGRSV-RFRADELFPMCSLFKTLAAAAVLRDLD +RHGEVLARRIHYTEADLVQGSDQTAAHLAEGMTIAELAEVAITHSDNTAGNLLLRELGGP +TAITRFARSLGDRTTRLDRWEPELNTAEPWRLTDTTSPYAIGRTYGRLVLGDALDRRDRR +LLTHWLLSNTTSVDRFHAGLPASWTIADKTGSGSYGTANDVGVVWTEKGDPIVLSVLSTM +PEPDAVRDDALVADAAAVVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. CNT312 TaxID=1137268 RepID=UPI00049164E3 +-----AEFARLEEDFDARLGVYALDTATGRTV-EYRPDDRFAHCSTFKVLAFGAVLKRTP +--VAELDRVVTFDRSDLVFHSPVAQGHVSTGMTLRELGDAALRYSDNTASNLLLEELGGP +DALNGALREIGDETTRVDRFAPEMAQALPGDTRDTSTPRAMATSLHAFALGDVLSEAGRT +VLVDMMRANTTGDGLIRAGVPENWEVGDKSGACGYGTRHDLGLVWPPGGEPVVLAVMSGR +DEAGAAYDDALVAQAAAQAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia yamanashiensis TaxID=209247 RepID=UPI000834C97E +---ATTAFADLESKHAARLGVFAIDTGNGRTV-GYREGERFPMASTFKGLACGALLDKHP +LSSGYFDQVIHYPATDLVDYSPETEKHVDTGMTVAELCKAAITLSDNTAGNQLLKLLDGP +AGLTAYLRTLGDATSRLDRWETELNTAIPGDERDTTAPGVLAADYRALTVGTELPEAERA +QLKSWLVASTTGGNRIRAGLPAGWTVGNKTGSPAYGSALDVAVAWPPNRAPIVIAVLTTK +SEQQAEPDNALVAAAARTAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. J1-007 TaxID=2661913 RepID=UPI0013254621 +--AVQRELRRLEASYKGRIGAYAVDTGTGRVV-SHRADERFGFASTFKSMAAAAVLRKAR +TDPGLMDRRLHWTRADVLDYSPITEKHVEDGLTVAEVCAAAVEYSDNTAGNLLLEQIGGP +AGLTRYLRSLKDPVSRLDHFEPELNPWKPGQKHDTTTPAAVGRDLSEVTLGRSVPAPDRA +RLIGWLKGNTTGDKRIRAGLPKGWTVGDKTGTGGYGTANDIAVAWPPSGAPIVLAIYTNR +RAADGEADDAVVARTATILA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI00023EAC13 +----KDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS +--IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP +ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE +LLIDFMKRNTTGDALIRAGVPDGFEVADKTGAASYGTRNDIAIIFPPKGDPVVLAVLSSR +DKKDAKYDDKLIAEATKVVMK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhizobium sp. NFR17 TaxID=1566260 RepID=A0A329AE82_9RHIZ +----EAQLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD +KGEEKLDRRIHYKKSDLIDYSPATEPNAGENMTVGELCAAAVTLSDNTAANLLLASFGGP +GAITTFCRSIGDEITRLDRTEPTLNYDTPNDERDTTTASAMLENLQRLLFTNVLTPASRS +QLAAWLITNKTGDARLRAGLPKDWLVGDKTGTNGHGNANDIAVLWPTKRAPIIVTAYCEI +PAIAADERNAIIGEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI00077E0157 +-------------------------------------EERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QFIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRVVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. 285MFTsu5.1 TaxID=1172187 RepID=UPI00037A3498 +---AEPDWAAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKALAVAAVLARVD +AGRETLDRVVSYGAGDLLSYAPVTRKALGTGMSVADLCAATLIWSDNTAANLLLADLGGP +EALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRVLLGTVLSPASRA +RLEAWMVACETGRKRLRAGLPPGWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTE +STASPDTCAAAYAEIGRLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID3212 TaxID=2690259 RepID=UPI00136E13AA +---LTRQLLALEEERSARLGVFAHDVATGRTV-LHRGHERFPICSVFKTLAVAAVLRDLD +RDGEYLSRRVRYTERDVVRHAPVTGANLAQGMTVEALCAASITHSDNTAANLLLGKLGGP +ASVTRFCRSVGDTVTRLDRWEPELNSAEPDRVTDTTGPYAVGRTYARLILGHALDPGDRE +RLTGWLLANTTGGARLRAGLPDDWTVAEKTGTGDYGTTNDVGVAWPPGRRPVVLSVLSTQ +EDPDAPADDQLVARTAALVT--- +>[subseq from] Beta-lactamase n=1 Tax=Pigmentiphaga sp. NML030171 TaxID=2008676 RepID=A0A208XW35_9BURK +--AALDELARLERLIDGRLGVCIVDTASGEEL-GRRADERFQMLSTFKLLAAGFVLARHD +RGEDSLDRRIRYTRQDLVNWSPVTGKHVGDRMTLAELCHATMTTSDNTAANLILRSFGGP +EALTRFIRGLGDGVTRCDRYEPELNVPHATGMLDTTTPHAITRTLGRLTVGEALSPASRE +RLQAWLVGNTTGDKRLRAGIPAGWRIGEKTGTYSKVGANDIGLAWPPARPAILMSVYVAS +TRVSDEVKDQVIAKVAELA---- +>[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A0V8JHY4_9BACI +--TIERKLAKLENKYDAKLGVYALDTGTNKTI-AYRPNERFAYTSTHKALAVGVLLQKNS +--IKDLDKRITYTRDDLVNYNPVTEKYVDAGMTLKELSDASLRYSDNTAGNLILEEIGGP +IGFKKALRELGDNVTNPVRMEPELNDVPPGEIADTSTAKALATSLQAFTLGDALPVEKRE +LLIDWMKRNTTGDALIRSGVPKNWEVADKTGAGLYGTRNDIAVIWPKKGDPIVLAVLSSR +NEKDASYDDKLIAEATKEVVK-- +>[subseq from] Beta-lactamase n=1 Tax=Shinella sp. WSJ-2 TaxID=2303749 RepID=A0A372NGW3_9RHIZ +----QEQLAELEARHKGRIGVAIHNLATNARL-SHRADERFLMCSTFKALLAGHILARVD +RKEEALDRRIVVKKSDLVEWAPVVEKRVGGKITIAELCEATITLSDNAAANLLLGASGGP +KAVTAFLRGFGDKVTRLDRSEPALNYEAPDDERDTTTPVAMTETLRKLLFTDVLSPRSKA +QLAAWLVMNKTGDTRLRAGFPADWMTGDKTGTNGAGNANDVAVAWSPNRGAIVVTAFVEM +PGISGDERNALIAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0007DC0F96 +--TIERKLAKLENKYDAKLGVYALDTGTNKTI-AYRPNERFAYTSTHKALAVGVLLQKNS +--IKDLDKRITYTRDDLVNYNPVTEKYVDAGMTLKELSDASLRYSDNTAGNLILEEIGGP +IGFKKALRELGDNVTNPVRMEPELNDVPPGEIADTSTAKALATSLQAFTLGDALPVEKRE +LLIDWMKRNTTGDALIRSGVPKNWEVADKTGAGLYGTRNDIAVIWPKKGDPIVLAVLSSR +NEKDASYDDKLIAEATKEVVK-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora rosaria TaxID=47874 RepID=A0A136PUH3_9ACTN +------RFAALEARFGARLGVYAVDTGSGRTV-AHRPDERFAYASTFKALAVAAVLEATT +--DAQYDRLVRYRRADLVAHSPVTGRHVAEGMTLRAVADAALRYSDNTAGNLLLAELGGP +RGFERALRGIGDTVTTPARVETALNQATPGDVRDTSTPRALATSLRTYAVDDHLDAGDRA +VLVDLLRRNTTGDALIRAGVPAGWQVGDKTGSGGYGTRNDIAVLWPPDGAPIVLAVLSRR +DTVDAPHDDALIAEAARVAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Kiloniella majae TaxID=1938558 RepID=UPI000A2786FA +----VETVTGLEESIGGRIGVAVYDLQTGQKW-EYRSDEKFPMSSTFKPFACAALLTQNE +RKDETLERMVSVSRDDLVSYSPVIEKYADDGVSLRKSCEATVSISDNTAGNLVLKEIGGP +EGFTRFMRSIGDNTTRLDRWETELNEAQPDDLRDTTSPKAIATSLQKLLLEDALSPEARI +EITNWMLNDRVADDLFRSRLPKGWKIADKTGAGGFGSRGIIAVIWPPSHKAVVASVYMTG +NDADFKTRNAAIAEIGAAIFE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-146 TaxID=1463884 RepID=UPI000D144155 +----TARLRELEQEHTARLGVYGRNLRTGRTV-VYRADERFPMASVFKTLAAAAVLRDLD +RDGEFLARRVHYTQEYVTKYSPITKDHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP +TAVTRFARSVGDRVTRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGTALEPRDRA +RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNNDVGITWPPDGPPIVMSVLTTQ +PEEDAP----------------- +>[subseq from] Beta-lactamase n=1 Tax=Marinisporobacter balticus TaxID=2018667 RepID=A0A4R2K910_9CLOT +--QYNSAFSQLESDYDVKLGVYAFDTETNKEV-VYRADDRFAYCSTFKVLAAGAVLKQDS +--LAQLKQTVKYDKKDVLSYAPIAKNNVDKGMTIEEICEAAIRYSDNTAANLLLDHIGGP +NGFKSVLNQLGDKITQPARIEPELNEGIPGDIRDTSTPRQLVTDLQAYITGNILTEDKKK +ILIGWMTGNATGNTLIRAGAPNNWVVADKSGTGPYGRRNDIAIVMPPNKKPIIIAILSTH +DTKEAKHDDKLIAQASKIVFDSf +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. Z26 TaxID=2500177 RepID=A0A498E5H0_9ACTN +--RAREEFDRLEGAYDARLGVYAVDTATGREL-TYRADDRFAFASTFKALLTGTGLQRDS +--VKDLEKRLTYDRDDLVPNSPITEKHVDTGISVRGAMDAAVRYSDNTAANLLFREYGGP +DAFEAALRRIGDRTTRSDRIETALNETTPGDPRDTSTPRAMADSLRAFTVGKALPVEKRK +ILTTMLRENTTGGPLIRAGAPEGWVVGDKTGAADYGTRNDIAVIWPPGRAPVMLAVLSDK +DTKDAEYDDALVADAAKAALAVf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SA15 TaxID=934019 RepID=A0A2A2Z3Q8_9ACTN +----TAELKELEREFDARLGVYAIDTGTGQEV-AYRDGERFGYHSTFKAMAAAAVLRTYS +--LSGMNEVIRYSVDDLVRNSPITEKHVDTGMTLRQLCDAAVRYSDNTAANLLFEALGGP +KGLEAELRKLGDDVTVMERIETGLSDWVPGETRDSTTPRAFAEDLRAYVLGDVLRKPERA +QLTKWLKTNKTGDELIRAGVPEGWVVGDKTGSGGYGGRNDIAVVWRPDAAPVVMAIMSNR +SEKDDTYDNKLIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus jostii TaxID=132919 RepID=A0A1H5MG08_9NOCA +--SLDAKIDELEARYSTRIGVTAVDPTTGVTY-SHRGDERFAMCSTFKAYASAAVLRATE +DGSASLDKAIVIEPADLVENSPVTAAAAGTPMSLGQIAEAALTQSDNTAGNYLLREIGGP +AAITALARDLGDESTRLDRWETELNTAFRGDPRDTTTPNGLTQGVRALLLGDALDTASRE +QLLDWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWTPDGDPIVLTILTDS +LTEDAQGNNQAIADTTAAVIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM2254 TaxID=1188263 RepID=UPI000400FDE0 +------ELEAYERESGGRIGLYAENLATGAKI-AWRADERFVMCSTFKASLAACVLARVD +RGQEQLAATIPYGQADLLSYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRIDHNEPEVNRSAPGDPHDTTTPAAMAGNLRRLVTGEALSPASRA +QLTEWMVGCKTSANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWTKPDTPILIAAYTQG +GSPTAPQIEAAFARIGRMVA--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis regifaucium TaxID=546365 RepID=A0A154M3F5_9PSEU +----RADFEQLERTFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFTAGGVLQRTP +--IAELDQTVTYSRQDVVTGSPVTEKHAGTGMSLRAVMDATLRYSDNTGGNLLFRELGGP +AGLTSVLRGIGDTTTHVDRIETELNDTAPGDIRDTSTPRALAVSLRAFALGDVLPEDKRK +ILVDIMRGNTTGDANIRAGVP-GWPVADKTGTASYGTRNDIAVVWPPNRAPIVLAVLTDR +STKDAKIDNALLARATAATVK-- +>[subseq from] Beta-lactamase n=1 Tax=Mixta sp. BIT-26 TaxID=2562439 RepID=A0A506VED7_9GAMM +--ALTQQLAALEKSAGGRLGVAWID-AGASHY-GYRADERFPMTSTFKTLAVAAILHQNV +SQPHLLEKKIAIEEADRVPWTPVTGSYFGKKMSVAALCAAAIEYSDNLAANYLLKEVGGP +QGITRYARYLGDSVTQLNRQEPELNSAVPGDKRDTTTPAAMAENLYKLTLGTALPTAQRQ +QLISWLQQSATGAESIRAGVPAGWRVGDKTGAGAYGSTNDIAILWPIKGAPKILAIYFTQ +PQPDAANNKAVLAAATRLAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Allosalinactinospora lopnorensis TaxID=1352348 RepID=UPI000623C7A5 +----AAEFERLEEEFDARLGVYALDTGTGLDV-AHRSDERFAYASTFKPLACGAVMERRS +--IAELEEVVGYGAEDLVEYSPITEEHVDTGMTLLEACDAAIRYSDNTAANLLFDELGGP +QGLQDALVEIGDDTTQADRRETGLNEAAPGDTRDTSTPEALAADLREYVLGDPLPEEKRT +LLREMLLENTTGGDLIRAGIPDGWEVGDKTGSAGYGTRNDIAVLWPPDGDPIVLAVLSSR +DGEDAESEDALIAEAAAVAAD-- +>[subseq from] Beta-lactamase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7KTM6_9BACT +-------FGSIERQVAGRLGVAVLDTATGRRL-AYRADERFAMCSTFKWLLGAQILSRAD +AGTEHLSRVVSYGETDLLEYAPVTRAHVREGMTISGLVSAAIQYSDNTAANLLLQTVGGP +ASFTAYIRQLGDRVTRLDRVEPDLNSAIPGDARDTTTPNAMVANLRVVLLGDHLGRAARD +QLIAWLVGNTTGAEKLRAGLPATWRVGDKTGMGAHGATNDVAITWPINRGPVLVAAYLVD +TEAGVAGRNDALANVGHAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces abyssomicinicus TaxID=574929 RepID=UPI0012509461 +-----TRLRELEERHGARVGVHARNMATGTTV-RHRADERFPILSVFKTLAAAAVLRDRD +TDGGFLDRRIRYTKAQLVENSDICEANLATGMTIRELCAAAIQWSDNTAGNLLLREIGGP +HGITRFARSLGDPVTRLDRWETELNSGEPWRETDTTSPAAIAATYARLVLGGALERPDRE +LLTSWLLGNRTGKTRLRAGLPPEWTIADKTGAADYGSLNDVGVVWTEDGTPLVMAVLTTK +PERDAPRSDILLEDVARVLVD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. MK-45 TaxID=2496836 RepID=A0A3S9MMM5_9ACTN +--DVSARLRALEEQHGARLGVFAHNLATKRTV-CHRADERFPICSLFKTLAAAAVLRDLD +RDGEVLNKRIHYTAADLVENSKQTEAHLATGMTVAELADVAIRFSDNTAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETDLNSAEPWLVTDTTSPRAIGRTYARLVLGNALNRPDRD +LLTHWLLNNTTSVNRFRAGLPKTWTIADKTGGGFYGANNDAGIAWTEDGTPLVLVVQTTQ +PEQDAAPDHALIVETAELLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces pharetrae CZA14 TaxID=1144883 RepID=A0A1Y2Q1U5_9ACTN +----TGRLRALEREYGAKLGVYAHNVGTGHTI-RHHADDLFPICSVFKTLAAAAVLRDLD +RDGEFLARRIHYTEADLVDGSDETGKHLAEGMTVAELCDVTIRYSDNAAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYARLVLGDALPGADRE +LLTHWLLNNTTSLDRLRAGVPPTWTVADKTGGGDYGVNNNVGIAWTPDGTPVVLAVLSRT +SDPAAVRENALIAKTAKVLTE-- +>[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A3R8UJS5_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA +GAISNEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis regifaucium TaxID=546365 RepID=A0A1Q4JJD9_9PSEU +----RADFEQLERTFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFTAGGVLQRTP +--IAELDQTVTYSRQDVVTGSPVTEKHAGTGMSLRAVMDATLRYSDNTGGNLLFRELGGP +AGLTSVLRGIGDTTTHVDRIETELNDTAPGDIRDTSTPRALAVSLRAFALGDVLPEDKRK +ILVDIMRGNTTGDANIRAGVP-GWPVADKTGTASYGTRNDIAVVWPPNRAPIVLAVLTDR +STKDAKIDNALLARATAATVK-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A1S2B316_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA +GAISNEQRATVLAQVGRIA---- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas TaxID=40323 RepID=UPI00050A19A1 +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA +GAISNEQRATVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. IF17 TaxID=1830119 RepID=UPI0011814E76 +-eALERAFAGLEERYDARLGVYAVDTGTGEEI-VHRADERFAYASTFKALAAGAVLLEYG +--TGGIDEVIPYGEEDLVEHSPVTGEHAGVGMTLRELCDAAVRHSDNTAGNLLFDALDGP +EGLNDTLREWGDGVTVMSRYETELNEAVPGDERDTSTPRALATNLRALLLEDLLEEAERD +LLTEWMLTNVTGSELIAAGVPEDWTVADKSGAGGYGTRNNIAVVWPPEGDPMVLAVLSAR +DVEGAEWDNALIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. S4.7 TaxID=2705439 RepID=A0A6C0PXA1_9ACTN +---TKAAFARLERRIDARLGVYAIDTGNGRSI-THRPDERFAYASTCKALLAAVMLDRYS +--LRQLDRLVRYDRNDLAGYSPITEKHIATGLTLRELCDATVRYSDNGAANLLFRELGGP +KSLQSALASIGDRVTRCDRYEDALSAAVPGDLRDTSTPRALATDLRAYVVDDALAPDKRA +VLTDWLKRNTTGDKVIRAGAPDGWQVGDKTGTGGYGTRNDIAVVWPPKAAPIAIAVLSRR +DFKDAEPDDALIAEAAGITL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. TM32 TaxID=1652669 RepID=A0A4Q1RVZ3_9ACTN +-dELSRRLTDLEQQHSARLGVFAHNTATGRSV-LHRADERFPMCSLFKTLAAAAVLRDLD +HHGEFLAKRIRYTQKDVRDYAPVTGTNLARGMTVADLCAAAISASDNAAGNLLLRELGGP +AAITRFCRSIGDRTTRLDRCEPDLNSAEPWRITDTTSPRAIGQTYTRLTLGTALTPEDRK +RLTGWMRATTTGGEKFRAGLPSDWTVADKTAGGKYGTNHDAGLTWPPGRSPIVMAVLTTK +REPDAAADNPLIAETAALLAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. Cp5.3 TaxID=443598 RepID=UPI0004122098 +------ELASYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLSAMIPYSQADLLEYAPVARQNLAAGMSVADMCKAIVELSDNTCANLLLARVGGP +AALTAFWRTIGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVLGESLSPASRG +QLTDWMVNCKTGANRLRGGLPGTWKIGDKTGNNGKDASGDLALVWPSPDKPLVIAAYTQG +GTPSPAQIEAVFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764) TaxID=1179773 RepID=K0K2Z6_SACES +-------WAGLERKFDARLGVYAVATGSGATF-AYRADERFAFCSTFKGLAAAAVLQRNP +--LAHLDTVVTYTDADLMKSSTITREHVATGMTIRDLCDAAVRYSDGTAGNLLVRDLGGP +AGLTAFLRGIGDGVTRADRTEPALTEAAPGDPRDTTSPRAIGTDYQRIVLGDVLPADKRA +FLRDLLERNTTGARRIRAGVPLGWVVADKTGTGEYGTVNDIGLGWQPNAAPLVIAVMSSK +TTTDAKYDEALIAEAAAQVV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ADI95-17 TaxID=1522759 RepID=A0A3N6G6L1_9ACTN +--RFARQFEDLERKYDARLGVYAIDTGTGREV-THNDAEHFAHASTFKALAAGAVLHKYS +--LGGMDEVIKYSKKDLVSDSPVSERHVGTGMSLSALCDAAVRFSDNTAANLLLDRLGGP +RGLDAVLADIGDDVTRMEHREPELNRWSPGATSDTSTPRALAGDLRAFVLGDLLGNGERA +QLTKWLRTNTTGAELIRAGMPRGWVVGDKTGSGGYGTRNDIAVVWRPDGAPVVVAILSNR +FQEDAEYDNALIAEAASVVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces coeruleorubidus TaxID=116188 RepID=A0A5J6IDG1_STRC4 +-----ALLRELEREHTARLGVYARNLRTGRAV-AYRADERFPMASVFKTLAAAAVLRDLD +RDGEFLARRIRYTQDYVTKFSPVTQENLATGMTVGELCDATIRFSDNAAGNLLLKELGGP +TAITRFARSIGDGVTRLDRWEPELNSAEPWRVTDTTSPRAIGLSYARLVLGDALEPRDRA +RLTDWLLRNTTSTEKFRKGLPADWLLADKTGGGRHGGANDVGITWPPDGPPIVLSVLTTQ +PEEDAAADNPLVARTAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=UPI000810A177 +-dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDHFPMMSTFKTLMCANALYLAE +QKKLNLNATTTVKESDLVTWSPITEKLTGQEIAVQKACEATMLMSDNTAANIVLHQIGGP +EQVTQFVRSLDDSVTRLDRFEPELNQATPGDKRDTTSPSAMVKLLNTLLLQDGLNQESQQ +QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPVILSIYLTQ +TQLDMAQRNRVINQVANLVFEQf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB865C +----EAQLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD +KGEEKLDRRIHYKKSDLIDYSPATKPNAGENMTVGELCAAAVTLSDNTAANLLLASFGGP +GAITTFCRSIGDEITRLDRTEPTLNYDTPNDERDTTTASAMLENLQRLLFTDVLTPASRS +QLAAWLITNKTGDARLRAGLPKDWLVGDKTGTNGHGNANDIAVLWPTKRAPIIVTAYCEI +PAIAADERNAIIGEIGRIAA--- +>[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2J0SYK5_STEMA +---AASDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPSLLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATVITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. 58S1 TaxID=1404864 RepID=A0A516J292_9BRAD +------ELESYERDSGGRIGLYAENLATGAKL-SWRADERFVMCSTFKASLAACVLARVD +RGEEHLAAMIPYGKADLLDYAPVAKQNLATGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTTFWRSLGDATSRLDHNEPELNRSPPGNPHDTTTPAAMAGNLRRLVTGEALSPASRA +QLTEWMVGCKTGANRLRGGLPANWTIGDKTGNNGKDASGDIAVVWPNTSTPILIAAYTQG +GAPNAAQIEAVFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. KE1 TaxID=1638939 RepID=A0A0H1ACS5_9ACTN +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLTAK +TEQDATRDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. JUb134 TaxID=2485112 RepID=A0A4R2YDT6_9SPHN +-----DPLAAIASEAGGRLGVSVLDTGTGRRL-WLDPLARYPLCSTFKVPLAAAILARAD +RGELDLQRPIRFTQGDLLDYAPVVRENLPRGMTLAELCAAAVEWSDNAAANLLLPQLGGP +SGLTRFLRSAGDTITRLDRVEPELNDYKPGELRDTTTPMAMTTLLAALLTGDVLEPASRK +QLTDWMIGCRTGDKRLRAGLPKSWRVGDKTGTSGNGQANDIAIAWPPSRKPILIACYLDA +PGIAPEKADQAIASVGSLVGQL- +>[subseq from] Beta-lactamase n=1 Tax=Salinisphaera sp. TaxID=1914330 RepID=A0A2E0IYA6_9GAMM +----IAAIRDLEARYGGRMGVAVHDAALGRAV-AHRGDERFLMCSTVKLPAAAMILSRVD +AGRESLDRHIDYAAADLVTYSPATERRVASGMTLGAICRAGLTLSDNTAANLMLASVGGP +AALTVFLHSLGDNVTRSDRYETALNEHAPDRLHDTTSPRAMLGLMQRVLLGDVLSAPSQR +QLVTWMRANETGDHRLRAGLPDAWRIGDKTGSGGDNTANDIAIIHPGVGAPLLVTAYYAG +SNATKTQRDRVLADVGRAV---- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhizobium miluonense TaxID=411945 RepID=A0A1C3UE17_9RHIZ +----EAQLAALESKHPGRICVSILDMGSGKRI-EHRAGERILMCSTFKALVAALVLSRVD +KGEEKLDRRIHYTKSDLLGNSPATEANVGETMTVAELCAAAVTLSDNAAANLLLASFGGP +KELTAFCRSLGDEITHLDRIEPELNYDTPDDQRDTTTAAAMLENLRRLLFTDVLSPASRS +QLAAWLIMTKTGDARLRAGLPKNWLVGDKTGTSDVGNANDIAVLWPSNRAPIIVTAYCEI +PGIAADERNAVIAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia altamirensis TaxID=472158 RepID=UPI0014355804 +-------FTDMEAKYGARLGVFAVDTGTGRTV-TQRDGERFPIASTFKGLACGALLRDHP +LSTGYFDQVIRFPATDIVANSPITETRVDTGMTVAELCHAAITVSDNTAGNQLLKLLGGP +EGFTAFLRSIGDQTSRLDRWETDLNTAIPGDDRDTTTPAALAADYRALVVDDVLAKPERD +QLTTWLVANTTGATRIRAGLPADWRVGDKTGTPAYGCALDVAVTWPPGRAPLVIAALSAK +DQEHAEPANALIADATKAVVT-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI00101E781A +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSVTASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALDPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Kibdelosporangium aridum TaxID=2030 RepID=A0A1W2B1E8_KIBAR +----HDQLFDLERRFDARLGVYAIATGSGATI-VHRSDERFAFCSTFKGLAAAAVLHRNP +--MAHLDTVLTYTEADLMKSSAITKRNVATGMKIRDLCDAAVRFSDGTAGNLLLRDIGGP +AQLTAYLRGLGDDVTRMDRIEPTITEAKPGDPRDTTTPRAIGTDYQRIVLGDALAADKRD +FLRDLLERSVTGAKRMRAGVPQGWRVADKTGTGDYGTLNDIGVVWPPDAPPLVIAIMSSK +SAADAKYDEAVIAEAAAYVVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Tu 6176 TaxID=1470557 RepID=UPI00055D39E6 +--------RALEERYSARLGVHARNTRTGQSV-GYRAGERFALCSTFKVFAAGAVLRDHA +-GSAPLDKVVRYPDRDILLNSPVTQQHVGSGMTVGELCAAAIRHSDNCAGNLLLRELGGP +AGLTAFFRSLGDRVSRLDRWEPDLNSAGPGELRDSTTPEALGASLERLTVGDELSGAARE +QLLTWLKGNTTSDRRFRAGLPRGWVVGDKTGTGDYASANDIGVAWTTRGTPLVLVVLTSK +DAPDATVDEALIADAAAVLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Marinobacter salarius TaxID=1420917 RepID=W5YPJ8_9ALTE +--------KTVEQRLDARVGIALYDSGTGESW-DYHGDDRFPITSTFKTLACAALLAKVD +NGTVDLDRRVIFSKDDLVTYSPVTETRAEEEMSLRELCEATMATSDNTAANLVLGAIDGP +DGVTAYARDLGDTVTRLDRTETSLNEATPGDLRDTTSPKAMVANLRKLVLGEALSKGSRD +TLVTWLKGNRVSDNLLRAAIPPDWTIGDRSGAGGHGSRSITAVLWPPHRPPLVIAIYITQ +TDASFDERNGAIRDLGGAIVKHf +>[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium sp. RAC02 TaxID=1842534 RepID=A0A1B3MEG8_9RHIZ +--ALEKRLAELEARHDGRLGVAILNLATGARL-GHRTDERFLMCSTFKALLAGHILARVD +REEEALDRRIVVKKSDLVDWAPVVEKRVGGDISIAELCEATITLSDNAAANLLLAASGGP +KAVTEFLRGFGDDITRLDRTEPALNYETPDDERDTTTPVAMVETLRKLIFGDVLSPRSKA +QLAAWLVMNKTGDTRLRAGFPADWMTGDKTGTNGAGNANDVAIGWSPNRGAIIVSAFVEM +PGISGDERNAVIAEIGRIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A1A6XSS0_STEMA +----ATDFAALESACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RALALLDRRVPVRGADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGDVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDVAVLWPLGGAPWVLTAYLQA +GAISNEQRARVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_055 TaxID=2175633 RepID=UPI000DAA14B3 +---TARAFAVLERRYDARLGVAAIDTGSGRTI-VHRAGERFAFASTIKVFIAAAVLDASS +--DADLATLVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTRVDRVEPDLNEATPGDPRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRIADKTGTASYGVRNDIAVVTPPGRDPIVLVVMTSR +ADAGAEPSDALVAAATRTAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rhizosphaericus TaxID=114699 RepID=UPI0013D90569 +--TVAGEFKKLERSYDAHLGVYAIDTGTGHEV-AYRDGERFAFASTFKALEAGAVLRKYK +--LSGLDRVIRYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGP +KGLDAILEKLGDDVIQMENIEPELSRWVPGETHDTTTPRAMAKDLRAFVLGDVLGKGERA +QLTKWLRTNTTGDELIRAGMPKGWQVGDKTGSGSYGARNDIAVVWRPGAAPLVMAIMSYR +GDKDTPFDNKLIADAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. TaxID=409 RepID=A0A2E7YJA8_9RHIZ +------DWGTLERRLDGRLGIAAA-TADRVLA-AYRADARFPMCSTFKVLAVAAVLARVD +TGRETLDRIVAYGSGDLLSYAPVTRKALEAGMTVSDLCAAAIVWSDNSAANLLLASLGGP +EALTAWLRDTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRASLGRILLGTVLSPASRG +RLEAWMIACETGRKRLRAGLPPDWIVGDKTGSGDNGSVNDIAILRPPGRAPVVVAVYVTG +STASAETYAAAYAEIGRLIA--- +>[subseq from] L2 family class A beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=UPI000DAABFAC +----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATALSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5727 TaxID=1463871 RepID=UPI0004C512CC +----VARLRALEEQYDARLGVHAHDVCTGRTL-AHRDRERFPMCSVFKTLAAAAVLRDLD +HDGTFLARRLTYTADYVERWSPVTKDNIARGMTVAGLCDATIRFSDNTAANLLLRELGGP +TAVTRFARSLGDPVTRLDRWEPELNSAEPWRITDTTTPRAIARTYGRLVLGKALEPADRA +LLTDWLLRNTTSLHRFRKGLPADWTVADKTGGGEYGGNNDVGVTWPPDGGPILLSVLTTR +FEPDAEGVDELVAAAAAIVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia altamirensis TaxID=472158 RepID=UPI000B003D12 +-------FTDMEAKYGARLGVFAVDTGTGRTV-TQRDGERFPIASTFKGLACGALLRDHP +LSTGYFDQVIRFPATDIVANSPITETRVDTGMTVAELCHAAITVSDNTAGNQLLKLLGGP +EGFTAFLRSIGDQTSRLDRWETDLNTAIPGDDRDTTTPAALAADYRALVVDDVLAKPERD +QLTTWLVANTTGATRIRAGLPADWRVGDKTGTPAYGCALDVAVTWPPGRAPLVIAALSAK +DQEHAEPANALIADATKAVVT-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. V2 TaxID=1424099 RepID=A0A2V1NTU4_9ACTN +-----DVFAGLEEEYAARLGVFAHDTATGRTL-THRADERFPMCSVFKAPAAAAVLRE-- +--GLDPTKRIHYTQQELTDYAPVTEKHLDTGMTVGELCAAAVSHSDNAAANFLLRELGGP +TAITRFARSLGDPVTRLDRWEPDLNSAEPWRTTDTTTPHAIARTYAKFLLGDVLRPADRT +RLTSWMVANSTNVTRFRAGLPADWILADKTGGASYGVANDVGVVWPPGRAPLVIAVLTTT +YAAEGPSKNELVAKAAARVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium radiotolerans TaxID=31998 RepID=UPI0005E98AD3 +----EPDWTAIERRLGGRLGIAAAS-ADGVLA-AYRADARFPMCSTFKVLAVAAVLARVD +AGRETLGRIVTYGPGDLLSYAPVTRKALEAGMSVADLCAATLVWSDNAAANLLLADLGGP +AALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRILLGTTLSPASRD +RLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGDNGTVNDVAILRPPGRAPILVAVYVTG +STASPDACAAAYAEIARLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Hydrogenovibrio sp. Milos-T1 TaxID=90813 RepID=UPI00057118BE +-eSFDQQVHELEQTYGGRLGVSIWDSDSNTSL-HYRGGERFAFCSTFKFLLVAAILKKVD +DKQLALDQQIPYGTSDLLSYAPITRKHLKSPMSISQLSAAALQYSDNTAANLLMKQVGGT +KGLTAFMQSIGDKTTRFDRIEPDLNSNLPNDERDTTTPDAMLKAMKQILLGSVLSHASRD +QLTQWLLNNTTGANKLRSGFPTFWPVGDKTGSGDNGATSDIAITWPDPDHPILVAVYYTD +SKQPFEIKNHVIELIGKIISEQf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. MKU004 TaxID=1849370 RepID=UPI0007E2E4C2 +------SFQDLEKQYDAKLGVYALDTGSGESV-SHNADERFAYVSTHKALAVGVLLKNKA +--IDELDERIKFTKEDLVDYSPVTEKHVDTGMTLRELSDASIRYSDNTAGNLILESIGGP +LGFKEVLREIGDDVTEPERTEPELNYVEPGETRDTSTPKALVKSLEAFTLEDILTEEKKN +LLNDWLKRNTTGDALIRAGVPEGWAVGDKTGAGSYGTRNDIAVIRPPDGDPIILAVLSSR +EERDAELDDELIAKAAELAIK-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Rc3b TaxID=1855322 RepID=A0A1I4QF62_9BRAD +------ELETYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACMLARVD +RGEDQLAAMIAYGKPDLLDYAPVAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGNPHDTTTPAAMAGNLQRLVVGEALSPASRA +LLTDWMVNCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWPKPGTPILIAVYTQG +GTPNPAQIEAAFARIGRMAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. EGI 650086 TaxID=1840409 RepID=UPI00131BA2E8 +----HDRLAELERKFDARLGVYALATGTGATV-AYRADERFAFCSTFKGLAAAAVLHRNP +--PAHLDAVVAYTEADLMKSSLITRQHVATGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP +AELTAYTRSLGDTVTRMDRIEPLITEATPGDPRDTTSPRAIGADYQRIVLGDALPADHRA +FLRDLLERNATGAQRIRAGVPQGWTVADKTGTGDYGTLNDIAVVWPPKSAPLVIAVMSSK +AAKDAKYDQALLAEAAAYVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Arsenophonus endosymbiont of Nilaparvata lugens TaxID=1247023 RepID=UPI0005096617 +--ELANIVKQEEKKLNSRIGVAVIDTANKVTV-SYRGNERFPLNSTFKALLCGMLLNQVD +NGKIVLTESVQFEKGQLVAHSPVTEKFIAPLMNWKQLCAAAISYSDNTAANLIEKKVGGP +TSFTRFLRSIGDRVTRLDRFEPELNSAIPGDKRDTTTPVAISQTLQKLVLGDVLQPSSRQ +QLRQWMEDDKVANALLRSVLPAQWKIADKTGTGDHGSRSIISLVWPEKRQPLIVSVYITQ +TKATLAQSNEAIARIGKAIFS-- +>[subseq from] Beta-lactamase n=1 Tax=Kosakonia sp. CCTCC M2018092 TaxID=2492396 RepID=A0A3G9BKU9_9ENTR +-------IARLEEKLHARIGIAVIDTASGKSV-SYRGDERFPLNSTHKALLCGALLSKVD +RGEFALSDTTQFSKETLMDYSPVTSKFVAPKMSWQQVCSAAIEYSDNTAANLVAQKLGGP +QKVTAWFADLGDNVTRLDRKEPELNSAVPGDLQDTTTPLAVSHTLEKLTLGDALKPESRA +QLVQWMKDDKVADALLRASLPSGWEIGDKTGAGAYGSRSIISVVWPKKGQPIIVSVYITQ +TEATLAQSNDAIARIGKSIFE-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia vulneris TaxID=1141657 RepID=A0A0C1APL0_9NOCA +----TAELTALEQQYDAQLGLFAVDTGSGKTL-TNRADQRMPFLSTFKGLAAGALLQAHP +LATGYFDKVVHFTEADLVTYSPVTSTKVAEGMTIAQIADAAITQSDNTAGNLLLRELGGP +QGLTAFLRTLGDQVSRLDRWEPDLNTALPDDERDTTTPAALAADYRALVLGDALGAPERE +QLTKWLKTNTTGDKRIRAGVPAGWTTGDKTGTGDYGMANDAAVTWPDGGAPLVLAIQTRK +STKTAEPSNDLVAAATKLVVDK- +>[subseq from] Beta-lactamase n=1 Tax=Pseudosporangium ferrugineum TaxID=439699 RepID=A0A2T0RQE1_9ACTN +----NSGLSELEREYDARIGGFALDTGNGRTV-QHRATELFPLLSTFKVLASAAVLRRAR +TDPGLLDRVIHYDAADLVTYSPITSQHVEDGMTVAALCEAALTYSDNTAGNLLLRLLGGP +PAVTRYARGLGDPVTRLDRWETALNDWSPTELRDTTSAKAMGRNLQAVTLGQALHPEDRA +RLTGWLRMNTTGDARIRAGLPAGWVVGDKTGSSDYGAANDIAVVQPPSGAAIVLAIYTNR +NAPDATYDNTLVARTATALVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Kosakonia cowanii TaxID=208223 RepID=UPI0009736FCB +-------IARLEEKLHARIGIAVIDTASGKSV-SYRGDERFPLNSTHKALLCGALLSKVD +RGEFALSDTTQFSKETLVDYSPVTSKFVAPKMSWQQVCSAAISYSDNTAANLAAQKLGGP +QKVTAFFAGLGDNVTRLDRKEPELNSAVPGDLQDTTTPLAVSRTLEKLTLGDALKPESRA +QLVQWMKDDKVADALLRASLPSGWKIGDKTGAGAHGSRSIISVVWPKKGQPIIVSVYITQ +TEATLAQSNDAIARIGKSIFE-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonadales bacterium 66-474 TaxID=1895868 RepID=A0A1M3QIH7_9GAMM +---VAAQLAMLERKHGGRLGVAMLDTGSGKGA-GHRADERFLMCSTFKLLLAAAVLKRVD +EGRERLDRRIVFGKDVVLDWAPVTGKHVGRPMTVAELCEAAITLSDNTAANLLITRIGGP +GVVTGFARSLGDPHTVLDRMEPELN------PRDTTTPDSMLGDMQKLLLGDVLSQASRG +QLTHWLLNCQTGLHSLRAGVPDGWRVGDKTGQWDTGANNDIAIIWPPGRKPLLVAAYYMT +DTTDVAARKAVLAEVGRIAA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000DA3F721 +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDSRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. S45 TaxID=1641861 RepID=UPI00131BCE60 +------ELVAIERACGGRMGVYVRDTGSGGRL-LHRADERFPMCSTFKALMVGQVLSQVD +HGQVSLDKRIAYGRTDLLPTSPVTSKHVAKGLPLRELCAAVIEYSDNGAANLILREIGGP +ASLTAWLRGQGDAITRLDRNELALNSAIPGDPRDTTSPLAMGATFERLTLGDILKPASRD +RLQAWLAANTTGADRLRAGLPGPWTLGDKTGSNGADTANDVALIRPPGRAPLIAAVFVTR +AT-SQEAANHAIASVGALI---- +>[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus thuongxuanensis TaxID=1873484 RepID=A0A1Q5U7K3_9GAMM +--EITHRLSILEKNANGRLGVVLIDTADHSTI-SYRANERFPLCSTSKLMAVSAILKQSE +TNVHLLNQRVHYQQSNLVEYSPITEKYLNDGMTLRELSAATLQYSDNTAMNLLLNQLNSP +SEVTRFARTIGDNSFRLDRHEPELNTAIPGDKRDTSTPQAMAKSLYNLVLGNALATTQRE +QLTEWIKGNTTGGASIRAGVPKDWIVGDKTGRCDYGTTNDIAVIWPVNRAPLVLVTYFTQ +PDKEASARPDVLAAATSIVTN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ST1015 TaxID=1848900 RepID=UPI000DDA09F1 +-------FAGLEEEYAARLGVFAHDTATGRTL-THRADERFPMCSVFKAPAAAAVLRDGV +----DPAKRIHYTQQELTDYAPVTEKHLDTGMTVEELCAAAVSHSDNAAANFLLRELGGP +TAITRFARSLGDPVTRLDRWEPDLNSAEPWRTTDTTTPHAIARTYAKFLLGDVLRPADRT +RLTSWMVANSTNVTRFRAGLPADWILADKTGGASYGVANDVGVVWPPGRAPLVIAVLTTT +YAAEGPSKNELVAKAAALVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Micromonospora sp. 5R2A7 TaxID=2202421 RepID=A0A317D7J8_9ACTN +--SADRQFGELERRFGARLGVYAIDTGTGRTV-THRADERFAHASTFKALLAAVLLRRLS +--DEDLRRVVTYTEADLLEHAPITSQHVATGMPVEDLIAAAVRYSDNTAANLLLNEIGGP +KGLQGELRKIEDRTTNINRNEPTLNEAVPGDDRDTSTPRALGTDLRTFALGDVLPKARRL +KLTDLLIGNTTGGPYIRAGVPSDWKVGDKTGSGGYGTRNDIAVVWPPTGSPLIIAIQSDR +GVPDASSADPLIAEATKVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TLI_146 TaxID=1938858 RepID=A0A2N3W7D4_9ACTN +------DFKELERKYGARLGVYAVNTGDGREV-GYRDGERFAYASTFKALAAGAVLRKYS +--LKGMTKVVKYSKDDLVTNSPVTEKHVDTGMTLGELGDAAVRYSDNTAGNLLFDALGGP +KGLESALRQTGDAVTRVERREPDLNQWAPGTLRDTSTPRALAQDLRAFVVGDRLGTAERA +QLTRWLRTNTTGDALIRAGVPKGWTVGDKTGAGGYGIRNDIAVVWPPGAAPIVMAILTNR +GTKDADFDNKLIADAAAVVAR-- +>[subseq from] Beta-lactamase class A n=2 Tax=Amycolatopsis saalfeldensis TaxID=394193 RepID=A0A1H8THS3_9PSEU +--SVQPELAALEKEFGGRLGVSAVDTGNGATA-GYRADERFLLCSTHKVLAVSALLHGHP +---DALDKVIHYDKAQLVTYSPVTSLHVADGMTGAAICEAAITVSDNTAANLIVGQVGGP +AAVTAFVRALGDPETRLDRLEPDLNVGAPGDERDTTTPARMAADLRALVLGSGLDPAGRE +RLTGWMVANTTGGKQVRAGVPAGWRVADKTGSGSHGESNDVAVVWPTGRAPWVIAVYTAP +SDPKSTAGPATIAEATRIVAKAf +>[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. 6K520 TaxID=2530364 RepID=A0A4R5EFJ0_9ACTN +--KVTEQIRRLEKARDMRIGAYILDMGTGRAL-GHRADETFPFASTFKAMACGAALQKAR +RDPGLMDRVIRYKESDLSPHSPVTEKHVKTGMTVADLCHATITKSDNTAGNLVLKQIGGP +AGLTAFFRSLGDRVSRSDRWEPALNDWRPGEKRDTTAPRVWAADLGSLTVGDALVPADRK +RLVGWLKATVTGDERIRAGLPDGWTAGDKTGTGGYGSANDIAVAWPPSGAPVVIAILTTK +RTPDADPDEQAIARTTTILIQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Mixta theicola TaxID=1458355 RepID=UPI00136342B6 +--ALTQQLAALEKSAGGRLGVAWID-AGASHY-GYRADERFPMTSTFKTLAVAAILHRNV +SQPHLLEKKIAIEEADRVPWTPVTGSYFGKKMSVAALCAAAIEYSDNLAANYLLKEVGGP +QGITRYARYLGDSVTQLNRQEPELNSAVPGDKRDTTTPAAMAENLYKLTLGTALPTAQRQ +QLISWLQQSATGAESIRAGVPAGWRVGDKTGAGAYGSTNDIAILWPIKGAPKILAIYFTQ +PQPDAANNKAVLAAATRLAIK-- +>[subseq from] Beta-lactamase class A n=3 Tax=Streptomyces TaxID=1883 RepID=A0A2N0GNX3_9ACTN +--RVAEALKRLEREHGARLGVYALDTGTGRAV-THRADELFPMCSLFKTLAAAAVLRDLD +HDGSVLARRIHYTLDDVERISEWTKRNLANGLTIGELCEVSITYSDNTAANLLLRELGGP +SAVTRFARSLGDRVTRLDRWEPELNSAEPERVTDTTTPRAIGRTYARLVLGDALARPDRE +LLTRWLCANTTSSERFRKGLPAGWRLGDKTGGGSHGTNNDVGIAWRPAGAPLVLAVLTTK +PAQDADADNALVARTAALLAEAf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. DASNCL29 TaxID=2583819 RepID=UPI00110F8AE2 +--AVAGEFKKLERSYDAHLGVYAIDTGTGHEV-AYRDGERFAFASTFKALEAGAVLRKYK +--LSGLDRVIRYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGP +KGLDAILEKLGDDVIQMENIEPELSRWVPGETHDTTTPRAMAKDLRAFVLGDVLGKGERA +QLTKWLRTNTTGDELIRAGMPKGWQVGDKTGSGTYGARNDIAVVWRPGAAPLVMAIMSYR +GDKDTPFDNKLIADAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium luteum TaxID=33881 RepID=A0A175RVX1_9MICO +---ADSAFAALERGSDARLGVVAVDTESGTTL-AYRGGDRFPFASTNKVFIAAAVLDRSS +--AADLDTVVHYDRGDLLAYAPVTARHVDTGMTVLELVDAAVSMSDNTAANLLVERLGGP +DAVEAWLRGIGDRTTRVDRLEPELNAATPGDVRDTSTPEQFAADLRDVLLGDVLDADDRR +VLQRAMLATTTGDGTIRAGVPSGWRVADKTGTGEYGVRNDIGLVTPPGRRPIVLVVMTRT +DRPDAGPSDALVAEATRTAV--- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. CNU-125 TaxID=1904961 RepID=A0A1Q9SUT8_9ACTN +-----RRLSKLEAKRNLRIGAYAIDTGTGRFV-SHRAGQRFPYASTFKAMACGAVLQKAR +TDPGLMERVIHYTEDDLVDYSPETEKHVGTGMTVSALCHAAITQSDNTAGNLVMKQLGGP +AGLTRFFRSLGDDASRADRWETALNEWKPGERRDTTVPAAWAGNLRALTAGDALAPADRE +RLIAWMKANTTGDARIRAGLPDSWTIGDKTGTAGYGNANDIAVAWPEGDAPLIMVVLTTA +KKKDAEADDAAIAETAAILA--- +>[subseq from] Beta-lactamase n=2 Tax=Pseudomonas fluorescens TaxID=294 RepID=A0A5E6RYY9_PSEFL +--QLGATATQIERRTGGHLGISVMDVASGAQW-SYRGDQRFPMASTFKAFTCASLLSQVD +QGRLDLSQRIAFTQDELDSYSPVTRDHVGGQLSLLQLCDAATSMSDNTATNLVLKTVGGP +AGLTAFMRSIGDNSTRIDRYEPELSDVPPGDPRDTTTPNAAAKSLQALLLGDVLSDASRQ +QLETWLVANKVSAALLRASLPEGWKIADRTGAAEYGSRGIIAVIWPETHGPVVVAAYLTG +TRLSLEERDTVLAEVGAALV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5193 TaxID=1463860 RepID=UPI00068A5169 +--AAAARFRALEERYGARLGVHAHDVRTGRTL-AHRDDERFPMCSTFKTLAVAAVLRDLD +HDGTFLARRLHYTAAYVARWSPVAGSNIARGMTVAELCDATIRFSDNTAANLLLRELGGP +TAITRFARSTGDPVTRLDRWEPRLNSAEPWRITDTTTPRAIARTYGRLVLGRVLEPADRA +LLTDWLLRNTTSLARFRKGLPADWTVADKTGGGEYGTNNDVGVTWPPDGGPILLSVLTTR +PEPEAGGVDELVAAAAAVVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Actinoalloteichus sp. GBA129-24 TaxID=1612551 RepID=A0A1L7FAU1_9PSEU +-----AELADLESRFGVRLGVYAHDTGSGTVV-AHRADERFPMCSTFKALLGAAILHESS +--TVELDRHFTWSEADLLYHSPITEGNVASGMSAEQLCDAAIRYSDNTAANLLLTEIGGP +AGFTAFVRTLGDDVTRLDRIEPDLSTGEPGDERDTTTPAAFAGDLRSLVLGDALASERRV +MLTDWLVGNTTGEGRIRAGTPEGWRLGNKTGSGGYGTVNDTAVLWPPDREPILLTVYTTM +GVRYAEYDEAVIAEASSIAL--- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacteria TaxID=2 RepID=A0A5B2VFQ9_9BACT +--------------------------------------ERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATKDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Nocardia puris TaxID=208602 RepID=A0A366DBE2_9NOCA +--DLAAEFAALETEFDARLGVYAIDTATGREI-AHHADDRFAFASTHKALTAGALLERNT +--LAELERVVTYTEADLLEHAPITEQRVATGMTLLELIDAAVRYSDNTAANLTMAELGGP +QGFEDALRAIGDNVTESDRWEPDLSDYTPGDPRDTSTPRAMATSLRAYTLGDLLPPDRRA +TLVDLLVRNTTGDTTIRAGVPEDWIVGDKTGSANYGTRNDIALLWPQEGAPIVVAIMSNR +GQEDAARRDELVAGAARVVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium japonicum SEMIA 5079 TaxID=476282 RepID=A0A023XSQ0_BRAJP +------ELESYERETGGRIGVYAENLATGAQL-AWRADERFVMCSTFKASLAACVLARAD +RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVVGEALSPASRT +QLTEWMVGCETGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKNKVPILIATYTQG +GTPNAAQIEAAFARVGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. B183 TaxID=1526762 RepID=A0A086WLA7_9VIBR +-dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDRFPMMSTFKTLMCANALYLAE +QKKLNLNATTKVKESDLVTWSPITEKLIGQEITVEKACEATMLMSDNTAANIVLHQIGGP +EQVTQFVRSLDDKVTRLDRFEPELNQATPGDKRDTTSPSTMVELLNTLLLQDGLNQEPQQ +QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPIILSIYLTQ +TQLDMAQRNRVINRVANLVFEQf +>[subseq from] Beta-lactamase n=2 Tax=Saccharopolyspora erythraea TaxID=1836 RepID=A4F9H1_SACEN +------ALAELERRYDARLGLTAVNVRTGREL-KHRADERFAMCSTFKTYAAGALLAAHP +LAGGYFDKVIRYTRADLRPNSPVTETRVDTGMTVAELCEAAITRSDNAAGNLLLAELGGP +AAIAPFARSIGDPTTRLDRWEVELNTAIPGDERDTTTPAGIAAGYRAMVVGDALGAPERE +QLKKWLIANTTGGERIRAGLPPNWVTGDKTGSGDYGTANDVAVTWTESGDAIVIAILTSK +SAPDRKYDNRLHADTARIVVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4P8JF72_ECOLX +------------------------DTADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA +QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ +PEQKAESRRDVLXAAAKIV---- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1) TaxID=426355 RepID=B1M0E1_METRJ +----EPDWTAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKVLAAAAVLARVD +AGRETLGRIVTYGPGDLLSYAPVTRKALEAGMSVADLCAATLVWSDNAAANLLLADLGGP +AALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRILLGTTLSPASRD +RLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGDNGTVNDVAILRPPGRAPILVAVYVTG +STASPDTCAAAYAEIARLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis regifaucium TaxID=546365 RepID=UPI0009ECF7A6 +----RADFEQLERTFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFTAGGVLQRTP +--IAELDQTVTYSRQDVVTGSPVTEKHAGTGMSLRAVMDATLRYSDNTGGNLLFRELGGP +AGLTSVLRGIGDTTTHVDRIETELNDTAPGDIRDTSTPRALAVSLRAFALGDVLPEDKRK +ILVDIMRGNTTGDANIRAGVP-GWPVADKTGTASYGTRNDIAVVWPPNRAPIVLAVLTDR +STKDAKIDNALLARATAATVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia concava TaxID=257281 RepID=UPI0009FD1E16 +-----PAFRTLEQDHGARVGVFALDTGTGKSI-GYRQNERFTINSTFKSLACGALLRAHP +LNTGYFDQVVHFTADEIVSASPVTQTRVDSGMSVTELCEAAITRSDNTAGNQILKLLGGP +QAVTDFARSLGDQVTRLDRWEPDLNTDIPGDERDTTSPAALAADYRALVLGDVLATPERK +QLTDWLLANKTGDARIRAGIPADWKTGDKTGSGDYGTANDAAVTWPADGPPLVIVVLSSK +PDQAAPADNPLVAAAAKEAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces exfoliatus TaxID=1905 RepID=UPI000463F7F3 +---TARAFGDLERKFDARLGVYAIDTGSGRTV-THRPDERFAYASTCKALLAGAVLDRNT +--LRQLDRLVRYGRDELVSNSPITERHLATGLTLRELCDAAVRYSDNAAANLLFRELGGP +RGLQDALRALGDDVTRCDRYEVALSDGVPGDLRDTSTPRALAADLRAYVLGTTLPADKRA +VLTDWLKRNTTGDHTIRAGTPDGWQVGDKTGSGGYGTRNDIAVIWPPGAAPIALAVLSRR +DTEGAERVDALIARATEVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces natalensis ATCC 27448 TaxID=1240678 RepID=A0A0D7CB98_9ACTN +--RTTARLRHLEHQHHAVIGAFAHNLATGAQV-RHRAHTRFPILSVFKTLAAAAVLRDLD +HHGETLSRRIRYTRRDLVDNSPITSQHLADGMTVADLCDAALRYSDNTAGNLLLRQLGGP +TAITRFCRSLGDPTTRLDRWETDLNSAEPWRRTDTTTPYAIAHCYGTLLTGRALDRRDRA +RLTDWLLHSTTSGERFRAGLPKDWTVADKTGSAGYGAANDVGIAWAPDGAPVVLAVLTRK +PGPSAPYDNPLIAETAKVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. UNC300MFChir4.1 TaxID=1502747 RepID=UPI0008C27119 +---AEPDWAAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKALAVAAVLARVD +AGRETLDRVVSYGAGDLLSYAPVTRKALGTGMSVADLCAATLIWSDNTAANLLLADLGGP +EALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRVLLGTVLSPASRA +RLEAWMVACETGRKRLRAGLPPDWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTE +STASPDTCAAAYAEIGRLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Ruegeria atlantica TaxID=81569 RepID=A0A0P1EB16_9RHOB +--PLTETVQSWERRLDARIGLLLYDPSKEWEV-SYRADELFPMSSTFKTLLCGAVLAEVD +AGTESLSDHVTYQSADLVDYSPVTSKHVETGMTVGALCEATVTISDNAAANLLLRRLDGP +AGLTEFLRTNGDDITRLDRWETALNEAAPGDPRDTTTPRAILATLDRLLFGQALSPASSA +QLRQWMIDDQVADGLIRAHVPDGWTIGDKTGAGGHGSRAIVAFLQTPEPRTYLAAIYLTE +SDAPFPERNAVLSDIGRAMIS-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinoalloteichus spitiensis TaxID=252394 RepID=UPI000A2ED613 +----EVAFDRVEREHDVRLGVYALDTGSGRVL-VHRADERFAYCSTIKALAAGAVLRVSS +--DERMDEVIPYRQADLVSHSPVTEDHVGTGLSLGALCEAAVRSSDNTAANLMLTELGGP +DGFQRVLRELGDEVTRSDRYETELNDAVPGDERDTSTPRALASTLRALLLGDALPGERRE +VLEDWMSNNATGDELVRAGVPSTWRVVDKSGGGYYGTRNDIAVAFRPDAPPIVLAVLTSR +TERDAEGRAEAVAAAARVVAD-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas bentonitica TaxID=1450134 RepID=UPI000C9C11DF +----AKDFAALEAASGGRLGVTLLNTGTGWRT-GNRQDERFPMCSTFKFVLSAAVLHLAD +QGRLPLDQRIPVRQQDMLSHAPVTTRHIGKDVTVRDLCRATMITSDNPAANLLLGVVGGP +AGVTAFLRANGDAVTRNDRLEPEMNRFTPGDPRDTTSPAAMAASLQRFVLGDVLKPASRQ +QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ATVDDAGRNDVLRQVAVI----- +>[subseq from] Beta-lactamase n=1 Tax=Pigmentiphaga kullae TaxID=151784 RepID=A0A4V2F2J8_9BURK +--AALDELARLERLIDGRLGVCIVDTASGEEL-GRRADERFQMLSTFKLLAAGFVLARHD +RGEDSLDRRIRYTRQDLVNWSPVTGKHVGDRMTLAELCHATMTTSDNTAANLILRSFGGP +EALTRFIRGLGDGVTRCDRYEPELNVPHATGMLDTTTPHAITRTLGRLTVGEALSPASRE +RLQAWLVGNTTGDKRLRAGIPAGWRIGEKTGTYSKVGANDIGLAWPPARPAILMSVYVAS +TRVSDEVKDQVIAKVAELA---- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00106FB613 +----ASDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFDVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMGGSLQRVVLGKVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas TaxID=40323 RepID=UPI0008A41527 +----AKDFAALEAASGGRLGVTLLNTGTGWRT-GNRQDERFPMCSTFKFVLSAAVLHLAD +QGRLPLDQRIPVRQQDMLSHAPVTTRHIGKDVTVRDLCRATMITSDNPAANLLLGVVGGP +AGVTAFLRANGDAVTRNDRLEPEMNRFTPGDPRDTTSPAAMAASLQRFVLGDVLKPASRQ +QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ATVDDAGRNDVLRQVAVI----- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM1253 TaxID=319003 RepID=I2QJM1_9BRAD +------ELEAYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEDQLAAMIPYGKADLLEYAPVAKQNIAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLRRLVTGEALSATSRA +QLTDWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKDTAPILIAAYTQG +GTPSAAQIEAVFARIGHIVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDF1B24 +----EAQLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAGLVLARVD +KGKEKLDRRIRYTESDLIGGSPATKAHVGDGMTVAELCAAAVTLSDNTAANLLLASFGGP +EAITAFCRSLGDETTRLDRIEPQLNYDTPEDLRDTTTAAAMLENLRRLLFADVLSAASRS +QLAAWLITTKTGDARLRAGVAKDWLVGDKTGTSDAGNANDIAVLWPANRAPIIVTAYCEI +PEIAAGERNAIVAEIGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia sp. CFHS0054 TaxID=2382165 RepID=A0A386ZHR3_9NOCA +-----TAFRNLEQQHNARIGVVAIDTGTGKTL-GYRQQERFAFDSTFKALACGALLHAHP +LSTGFFDQVRHFGSDKVVANSPVTSTRVDSGMTVAELCEAAITVSDNTAGNQILELLGGP +AALTAFLRSIGDQTTRMDRWEPDLNTNIPGDDRDTTTPAAIAADYRALVLGDTLAAPERT +RLTDWLLATKTGDTRIRAGLPADWKTGDKTGSGDYGTANDIAVTWPAGGAPLVIAVLTTK +PEQAAPFDNPLVAAAAKATVD-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A1I6JXY3_STEMA +----AMDFAALEKACAGRLGVTVLDTASGRRI-GHRQDERFPLCSTFKTVLAATVLDQSR +RVPGLLDRRVPVREADLLSHAPVARRHAGKDLTVRDLCRATIITSDNTAANLLFDVVGGP +PAVTAFLRAHGDSVTRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRLVLGDALAPAARQ +QLADWLIDNETGDACLRAGLGARWRVGDKTGSNGEDARNDTAVLWPMGGAPWVITAYLQA +ADISNDQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Virgibacillus sp. 7505 TaxID=2022548 RepID=A0A268HZE7_9BACI +-----ASFSSLEETYDARLGVFAIDTGSGRTV-AYRENERFGFASTHKALSVGVLLQQKS +--MEDLNKRIMFTGDDLVNYNPITEKHVDSGMTLKELSEASISYSDNTAANLIFEEIGGP +EGFEEGLRKIGDQVTNSESIEPELNNTVPGETRDTSTPKAMAESLRAFALEDHLAADKRQ +LLIDWLKGNTTGDALIRAGVPEDWEVGDKTGAGSYGTRNDIAILWPPGEEPIVLAIMSDC +DEADAKADDDLIAQAAEAVVT-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=D2CGR4_STEMA +---TANDFAALEMACAGRLGVTLLDTASGRRL-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATVITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPEMNSFAEGDPRDTTTPAAMAATLQRVVLGDVLQPASRQ +QLSDWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA +SAISNEQRAGVLAHVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Kibdelosporangium sp. MJ126-NF4 TaxID=703222 RepID=A0A0K3BMR7_9PSEU +-----AALVEVERKFDARLGMFALNTATGVTV-THRADERFAFCSTFKGLAAAAVLHRNP +--MSHLDTIVRYGKGDLLKSAVITSQHVTTGMTIRDLCDAAIRYSDGTAGNLLLRELGGP +QQLTEYLRGLGDSVTRMDRTEPAIVEATPGDPRDTASPRALGTDYQKIVLGDVLPEDKRA +FLRDLLERNTTGAQRIRAGLPPDWRVADKTGTGDYGTINDIAVVWPPGAAPLVIAVMSSK +AAKDAKYDQALIAQAASHA---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCCE4A +----EAELAALESRHPGRICVSILDMASGKRI-EHRARERILMCSTFKALAAALVLARVD +RGQEKLDRRIRYTKSDLVHGSPATKAHLRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP +KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS +QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI +PAIAADERNGIVAEIGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Root241 TaxID=1736501 RepID=A0A0Q8XDM1_9SPHN +--EFRRAVAAVEQASGGRLGLAIIDTGSGERF-GRRGAERFPMCSTFKFALAGLILKQVE +RKRETLARPIPVAAADIVANSPFCEARVGGSASIAELCHATITVSDNSAANLLLRTIGGP +SGFTRWLRSVGDPATRLDRWETEMGEARPRDVRDTTTPVAMAGLARRLLLGNALAPAGRA +QLTGWMKDTRTSRNSLRAGLPAGWTVADKTGAGGYGTDNLVAMVWPPRRAPLVVASYITG +STLEFEKRRPLHAGIGRAIVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. p1417 TaxID=2681492 RepID=UPI0012F6683B +----AQAFKQLERKFDARLGVYAVDTGTGREV-AYNDGRRFAYNSTFKALAAGAVLRKNT +--LAGMDRVVKYSKDDLLANSPVTEKHVDTGMSLRALCDAAVRYSDNTAANLLFDELGGP +KGLDAALERLGDHVTRVERIEPFLSRWVPGEKRDTSTPRALAKDLRAYVLGDVLAEPQRA +LLTRWLKTNTTGDHVIRAGVPKNWVVGDKTGTGTYGARNDIAVVWRPDAAPLVVAILSHR +ADKDAAPDDRLIAESASVVAD-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A649UHN4_ACIBA +----------------------------------WRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLAPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEH- +>[subseq from] Beta-lactamase n=1 Tax=Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) TaxID=479433 RepID=C7Q6I7_CATAD +-----AAFAQIAAHYQAQLGVYAVDTGSGRTV-GYQADQRFAFCSTIKALAAAELLHRDT +--DAQLAQTIHYSASDLVDYSPVTSQHVNDGMTLTAVMTAAIEVSDNTALNLMLDRLGGP +AGLQTALRGMNDATTDADRPEPAVNSAVPGDVRDTSTPRAMAEDLRAYVLGNALSPQRRA +LLTSWLTANTTGGPYIRAAVPAGWTVGDKTGNGDYGTRNDIAVLWPPHRAPIVIAVLSHR +DGKDATSADALIADATKVALQ-- +>[subseq from] Beta-lactamase n=2 Tax=Subtercola boreus TaxID=120213 RepID=A0A3E0VBQ8_9MICO +--DTTEDFEELEQRYQARVGVYAIDTATGSEV-GWRDDERFAYASTIKALAAAALLDQVG +--VSGLAKAISIDAADIVTYSPVTETRVGGNMTLGEIAEAALTVSDNTAANYLFEELGGP +DALGSALTEIGDDTTVVSRIEPELNEAVPGDDRDTSTPQALATSLEAYVLGDALPEAEAT +QLESWMTATQTGDDLVRADLPTDWTVGDKSGSGGYGTRNDIAIVWPTEGAPIVIAVMSSR +DDEDAESDDRLIAEAASTAID-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. MOE7 TaxID=1961713 RepID=UPI0009FFEE5E +---AVRKLRDLERRHGTRLGVFGWNTVTGRTV-LHRANERFPLCSTSKTMAIGAVLRDLD +HDGTFLSKVIHYTQQDIDRAAPVTGQNLAHGMTVADLCGAAVSYSDNTAMNLLLAELGGP +AAVTRFCRSLGDTVTRLDRCEPELNSAEPWRVTDTTTPRAIGNTYARLALGNALDKADRT +RLTGWLLANTTGGKRLRAGLPDGWTVGDKTGTGRYGTTNDVGIAWPPGQGPIVMAVLSTR +PAPDAEADDAVIAETAALL---- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM2793 TaxID=1038866 RepID=UPI0003810058 +------ELETYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACMLARVD +RGEDQLAAMIAYGKPDLLDYAPVAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGNPHDTTTPSAMAGNLQRLVVGEALSPASRA +LLTDWMVNCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWPKPGTPILIAVYTQG +GTPNPTQIEAAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces iranensis TaxID=576784 RepID=A0A060ZSY1_9ACTN +------RMRELEREYGARLGVFALDTGTGRAV-VHRADERFPICSVSKTLAVGAVLRDLD +RDGEYLARRIRYTEDDVKTHIPITGTNIANGLTVEELCAAAISYSDNGAMNLLLRQLGGP +TAVTRFCRSLGDGITRLDRWEPDLNSAEPGRVTDTTTPRAIGRTYAGLAVGRALEAGDRK +RLAGWLVANTTGDARIRAGVPGGWTVGDKTGTGRYGTTNDVGIAWPPDRAPIALAVLSTR +PEQDAEAVDPLIAKATALAVE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Jeotgalibacillus sp. R-1-5s-1 TaxID=2555897 RepID=A0A4Y8KVK9_9BACL +--TMNSSFEDLEKEYDTKLGVYALDTGNNQSV-AYNEDERFGYASAHKALAVGALLKKKS +--MEELDERINFTEEDLVNYNPVTEEFVDEGMTLKELSDASIRYSDNTAANLIFEAIGGP +EGFKEVLREIGDDVTEPARIEPDLNDVEPGETNDTSTPKALAESLQAFTLGDVLSEEKRE +MLNDWLIRNTTGDNLIRAGVPEEWIVGDKTGSGSYGTRNDIAVIWPPDEEPIILSILSSR +EEPDAEYDDELIAKAAEIAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Lysobacter antibioticus TaxID=84531 RepID=UPI0003466829 +---WNAQLTRLERDSGGRLGVAALDTGDGKRL-GWRGGERFPMCSTFKFLLAAAVLREVD +RGRLDLQRKLPIAKSDIIAHSPTTEPLVGVGASVATLCEATMTLSDNAAANLLLPLIGGP +AGLTRFLRSIGDPVTRLDRIEPELNVVGPGDERDTTSPDAMLDSLRTLVLGDALKPASRE +RLTAWLVANKTGDKRLRAGLPAGLRVGDKTGTANT-TANDLAAIWPAPRKPVLLTCYLTG +AGIDAAGRDQVHAEVARTLAQIw +>[subseq from] class A beta-lactamase n=1 Tax=Crossiella equi TaxID=130796 RepID=UPI000A3B4CD2 +---ADEAFLALERKFGARLGVSVVDTGSGRTL-AYRADERFAHASTFKALAAGVVLRRAS +--DADLDRVIQYTEKDLLEYAPITKQRVGTGMSLRELLDASVRYSDNTAANLIFTYLGGP +QALQRELRALGDVTIQVDRVEPALNEATPGDPRDTTTPAALATTLRALALGDALTPPRRQ +VLVELLQGNTTGGPYVRAGVPAGWRVGDKTGSGGYGTRNDVAVVWPDGGAPLVLALLSDR +GKPGAESGDALLAEATRAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. ABOLF TaxID=1985879 RepID=A0A430DP98_9SPHN +-----DPLAAIASEAGGRLGVSVLDTGTGRRL-WLDPLARYPLCSTFKVPLAAAILARGD +RGELDLQRPIRFTQGDLLDYAPVVRENLPRGMTLAELCAAAVEWSDNAAANLLLPQLGGP +SGLTRFLRSAGDTITRLDRVEPELNDYKPGELRDTTTPMAMTTLLAALLTGDVLEPASRK +QLTDWMIGCRTGDKRLRAGLPKSWRVGDKTGTSGNGQANDIAIAWPPNRKPILIACYLDA +PGIAPEKADQAIASVGALVGQL- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora avicenniae TaxID=1198245 RepID=A0A1N7EMQ1_9ACTN +------RFATLECKHDARLGVYALATGTGATV-AYRADERFAFCSTFKAFAAAAVLHRNP +--LQHLAERVTYTEADVNSISPITKNHVRSGMTIRQLCDAAVRYSDGTAGNLLMRDLGGP +AELTAYLRRLGDTVSRMDDYEPQLNRVPPHDPRDTTTPRAIATNYRKLLLGDALSADKRA +LLTGWLNHNTTGAKRIRAGVPKGWTVADKTGTGDYGRAVDVGVVWPPDTGPLVVAVMSDR +RGYDTPPVDVLISEATARVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004CDB55A +---TDRAFAGLERKFDARLGVYAVDTGDGRIV-AHRPDERFAYASTCKALLAGAVLAKKS +--LPQMERLVRYGKEEIISNSPITEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP +RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYVLGPALPAAKQA +VLADWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVRPPGGAPIALAVLSRR +DTKDAEPQDALIAGAAKIALEAf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces luridiscabiei TaxID=164114 RepID=UPI0006E35B8E +---TDRAFAGLERKFDARLGVYAVDTGDGRIV-AHRPDERFAYASTCKALLAGAVLAKKS +--LPQMERLVRYGKEEIISNSPITEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP +RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYVLGPALPAAKQA +VLADWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVRPPGGAPIALAVLSRR +DTKDAEPQDALIAGAAKIALEAf +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. B1 TaxID=91459 RepID=UPI0005B8F27D +----EPDWGALERRLDGRLGIAAA-TADRVLA-AYRADARFPMCSTFKVLAAAAVLARVD +TGRETLDRIVAYGSGDLLSYAPVTRKALEAGMTVSDLCAAAIVWSDNSAANLLLASLGGP +EALTAWLRDTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRASLGRILLGTVLSPASRG +RLEAWMIACETGRKRLRAGLPPDWIVGDKTGSGDNGSINDIAILRPPGRAPVVVAVYVTG +STASPETYAAAYAEIGRLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces bobili TaxID=67280 RepID=UPI000A369531 +-----ARLRALEEAHGARLGVFAYNVRTRRSV-RHRAAERFPVCSLFKVLAVAAVLRDLD +RNGEVLARRIHFTADDLVENSPETELHVADGMTVAELCDAAIRRSDNTAANLLLRELGGP +AAVTRFARSIGDRFTRLDRWEPELNSAEPWRVTDTTTPYAIGRSYARLVLGDELAAHDRR +RLTDWMLANRTSDNRFRAGLPPAWTLADKTGGGWYGANNDAGIAWTPDGTPVVLVVQVTM +PEREAAYDHALIVETTKLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces clavuligerus TaxID=1901 RepID=B5GLA6_STRCL +-----ADLAALEREHGARLGVYALETGTGAEV-AHRADERFAFCSTFKALAAAAVLHHHP +--IRHLERRVTWTRADVDSISPVTEDHIATGLTVGQLCDAAIRHSDGTAGNLLMRDLGGP +SRLTAYLRGLGDSVSRMDQYEPELNHDPPHDPRDTTTPRAIASDYRKLVLGDALTPDRRA +LLTDWLVRNTTGGRRIRAGVPSGWRVADKTGTGNYGRANDIAVLWPPRSSPLVVAVMSDR +PGFRTPPSERLIAEAAERIV--- +>[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis sp. AC402 TaxID=1282361 RepID=V4Q7H7_9CAUL +----AAAMLEITQRHGGRIGVSAVDTDSGARL-SVSSQDRFAMMSVFKWILAAAVLARVD +AGELKLDQVVRYGAKDLIAWSPVTEKKVKDGIAVGELCAATVSKSDNTAANLLLPLVGGP +DGLTKWIRSLGDEVTRCDRKEPELNANTDGDLRDTTTPQAMTQLLQIVFTGVALEPESIK +QMRAWMVATTTGDKRIRAGVPSGWTVANKTGTAN-GAVNDVAVIWPKTEGPIFLSIFTTG +GALEADAKEQVVADIARLVCEVf +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. XJLW TaxID=739141 RepID=A0A2U9TSF7_9RHIZ +----EPDWGALERRLDGRLGIAAA-TADRVLA-AYRADARFPMCSTFKVLAAAAVLARVD +TGRETLDRIVAYGSGDLLSYAPVTRKALEAGMTVSDLCAAAIVWSDNSAANLLLASLGGP +EALTAWLRDTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRASLGRILLGTVLSPASRG +RLEAWMIACETGRKRLRAGLPPDWIVGDKTGSGDNGSINDIAILRPPGRAPVVVAVYVTG +STASPETYAAAYAEIGRLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A0U5I5E2_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE +RVPALLDTRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=A0A1D7VNM5_9ACTN +---VVRKLRDLERRHGTRLGVFGWNTVTGRTV-LHRANERFPMCSTSKAMAIGAVLRDLD +HDGTFLSKVIHYTQQDIDRAAPVTGQNLAHGMSVADLCGAAVSYSDNTAMNLLLTELGGP +AAVTRFCRSLGDTVTRLDRCEPELNSAEPWRVTDTTTPRAIGRTYARLALGNARDTADRT +RLTGWLVANTTGGKRLRAGLPEGWTVGDKTGTGRYGTTNDVGIVWPPGRGPIVMAVLSTR +PEPDAEMDDAVIAETAALL---- +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBA1_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRTTIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +RAISYEQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Actinophytocola xanthii TaxID=1912961 RepID=A0A1Q8CVN4_9PSEU +-----ARLRELEAGFGGRIGVAARR--GGRTL-HYRAGERFAMLSTAKALVVAAVLHRAP +CDPGLLDLVVRYGADDLVEHSPVTERHVDAGMTVEALCDAAIRQSDNTAANLLLRQLGGP +DDLTRFARFIGDRVTRLDRWETELNSNLPGDPRDTTTPAAMAADLEALVLGDVLAAEDRE +RLTGWLVGNTTGDARVRAGLP-GWRVGDKTGTGAYGAANDIGVAWPPSGPPLVLAVFTTR +PEEAAEPADEVVAEIARVVAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Micromonospora globbae TaxID=1894969 RepID=A0A420ETS4_9ACTN +------GLVALERRFDARLGVYALDTGTAATI-AHRADERFAFCSTFKGLATAAVLHRHP +--LSYLETVVRYTRRDLMESSAITRRHVDTGMTLRQVCDAAVRYSDGTAGNLLLRELGGP +AALTAYVRSLGDTVTRMDRIEPTIVEATPGDPRDTTSPRAIGTTYRAILLGDALADDRRA +FLRDLMERNATGAARIRAGVPRGWTVADKTGTGDYGTLNDIGVVWPPGAAPLVIAIMSSR +AERDAAYDQALIAEAAAYVVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_043 TaxID=2175627 RepID=UPI000D8CF107 +--ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTIKVFIAAAVLDASS +--DADLATVVHYDRGDLLEYAPVTREHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP +NAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR +ADPGAEPSDELVAAATRTAV--- +>[subseq from] Beta-lactamase n=1 Tax=Pigmentiphaga sp. H8 TaxID=2488560 RepID=A0A3G8GUY6_9BURK +--AALDELARLERLADGRLGVCIVDTASGEEI-GRRADERFQMLSTFKLLAAGFVLARHD +RGEDSLDRRIRYSRQDLVNGSPVTGKHVGDRMTLAELCHATVTTSDNTAANLILRSFGGP +EALTRFIRSLGDGVTRCDRYEPELNVPHATGMLDTTTPHAITRTLGKLAVGEALSPASRE +RLQAWLVGNTTGDKRLRAGIPASWRIGEKTGTYAKVGANDIGLAWPPGRPAILMSVYVAS +TRVSDEVKDQVIAKVAELA---- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013C340CD +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKP---------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderiales bacterium 23 TaxID=2035215 RepID=A0A2G6TTH8_9BURK +-qAFRTELARIEKSVGGRLGVAVLEVESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ +QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP +QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA +LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE +CPADAPQRDAALAAAGKAAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces virginiae TaxID=1961 RepID=UPI00099C181B +---TAAGLRALEREYGARLGVYALDTASGRTV-VHRADELFPMCSVFKTLAAAAVLRDLD +HDGSHLAKRIHYTLQDVTDGGSITEKNIANGLTVAELCSAAIAQSDNAAGNLLLRELGGP +TAVTRFCRSLGDRTTRLDRWEPELNSAEPSRVTDTTGPRAIGRTYARLALGDALDPGDRE +LLNRWLLSNTTSGDRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPIVLAILSTM +PEATAPRDNTLIARTAKLLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CS227 TaxID=1982763 RepID=A0A209C6Y0_9ACTN +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLTAK +TEEDATRDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=3 Tax=Delftia TaxID=80865 RepID=A0A1D8IUJ0_9BURK +-qAFRTELARIEKSVGGRLGVAVLEVESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ +QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP +QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA +LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE +CPADAPQRDAALAAAGKAAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=F1CGM0_SHISO +----LEQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKA---------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia endophytica TaxID=401976 RepID=UPI00104392B3 +-----AELAGIESRFGGRLGLYALDTGTGRAV-GHRADERFLMCSTTKVPLIALVLRRSV +EDTGLLDRRIRWTRDDLLEYAPVTTPNLATGMTVAELCAAAVTVSDNTAANLLFAQVGGP +QAVTAFVRGLGDPLSRFDRVEPALNDTAPGDGRDTTTPARFAETLRLLTLGDALPPPQRD +RLVGWMDAATTGAAQIRAGVPAGWRVGDKTGSGNRGESNDVGVVSAPGRAPIVVTVFTAP +SDPDSTAGKPTIAAATRAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Paracoccus sp. PAMC 22219 TaxID=1569209 RepID=UPI000698EB1F +--TIEQAARAVEADLGGRVGVALRRHDDPTTH-GYRMDERFPLSSTFKVPLCGAILTLVD +AGEDQLDRVIGYVPGDLVSHSPVTEAHVADGMSVAQLCHATITQSDNTAANLLLDRVGGP +RDLTEYLRAIGDDTTRLDRWETDLNEGTPGDPRDTSTPAQMIDTLDALVLGPVLSDPSRR +QLEAWMQADAVADDLIRASLPNGWQIGDKTGAGGHGSRSIIAVIRPPQGGVWLASVYLTE +NDADMATRNRAIARIGAAMVD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderiales bacterium RIFCSPLOWO2_02_FULL_67_64 TaxID=1797564 RepID=A0A1F4J7Y2_9BURK +--AVQDSLRQIEATARGRLGVHIIDTATGREH-GWRSDERFLMLSSFKLLASALVLARAD +RGEESLERRILYRPQDLVSWSPVTEKHVGGELSLAQLCEATITTSDNTAANLILVSYGGP +AALTAFARRLGDTVTRLDRTEPALNRAASGEPLDTTTPRAMAHTVRKLLLGDALAPASRE +RLLDWLLANTTGGKSLRAGVPSGWRVGEKTGTAGD-DANDIGIAFPPQSAPLIVTAYLAE +SVTDGATREAALASVGRLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. MR-S7 TaxID=1268622 RepID=A0A0A1VEJ9_9BURK +----EREARRLEARLGGRLGMAVLDTDTGAFA-AHRGGERFALCSTFKLLLAAQILRRVD +ERRERLDARVHFGWGDLVEYSPRTEPHAGGAMTVAELCEAAMVLSDNTAANLLLRRQGGP +EGLTAWLRTLGDAHTRLDRTEPALNDVPPGEVRDTTTPLAMARTLQTLVLGDALAPASRE +RLQGWLLGNLTGDRRLRAGMPPGWRVGEKTGTAQ-GTGNDAGVVWPAQGAPAVVACYLTE +CPGAPALRDAAIAEAGALAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MOE7 TaxID=1961713 RepID=A0A1W5Y0W1_9ACTN +---AVRKLRDLERRHGTRLGVFGWNTVTGRTV-LHRANERFPLCSTSKTMAIGAVLRDLD +HDGTFLSKVIHYTQQDIDRAAPVTGQNLAHGMTVADLCGAAVSYSDNTAMNLLLAELGGP +AAVTRFCRSLGDTVTRLDRCEPELNSAEPWRVTDTTTPRAIGNTYARLALGNALDKADRT +RLTGWLLANTTGGKRLRAGLPDGWTVGDKTGTGRYGTTNDVGIAWPPGQGPIVMAVLSTR +PAPDAEADDAVIAETAALL---- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB34_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGVPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000D45FA60 +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAASVLSQAE +RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGDVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA +GAISNEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase class A IMI/SME n=1 Tax=Pantoea sesami TaxID=1881110 RepID=A0A1M5YUC5_9GAMM +-----DEIKSLETDFNGRIGVYALDTGSGKSF-SYRANERFPLCSSFKGFLAAAVLKGSQ +DNQLNLNQIVNYSTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDEVFRLDRWELDLNTAIPGDERDTSTPAAIGKSLENLALGNILSEREKE +TYQTWLKGNTTGATRIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +NQKEAKHDDKVIAEASRIAID-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. dk4132 TaxID=2662433 RepID=UPI001295D61E +----DEAFVALEKRYDARLGVFAIDTHTGETL-AHRADERFAYASTYKALAAAAVLARTE +--ARRWEEVVTYGADDLVTYSPVTEQHVGTGLSLRRIAEAAVRESDNTAGNLLLDELGGP +AGLQRALRGLGDDVTVVARRETALNDTSPGDRRDTSTPRAFAQVLQRYAVGDALRPPARR +TLLRWMRGNATGDTLVRAGVPDGWRVADKSGAAAYGTRNDIAVIEVPGRDPVVMVVFSDR +STADAEYDDALVAEAARVAL--- +>[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A246I949_STEMA +---TANDFAALEMACAGRLGVTLLDTASGRRL-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRMPVRDADLLSHAPVTRRHAGKDMTVRDLCRATVITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPEMNSFAEGDPRDTTTPAAMAATLQRVVLGDVLQPASRQ +QLSDWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA +SAISNEQRAGVLAQVGRIA---- +>[subseq from] Beta-lactamase n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A233RME5_9ACTN +---TDRAFAGLERKFDARLGVYAVDTGDGRIV-AHRPDERFAYASTCKALLAGAVLAKKN +--LPQMERLVRYGKEEIISNSPITEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP +RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYVLGPALPAAKQA +VLADWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVRPPGGAPIALAVLSRR +DTKDAEPQDALIAGAAKIALEAf +>[subseq from] class A beta-lactamase n=1 Tax=Actinophytocola xanthii TaxID=1912961 RepID=UPI000947189E +-----ARLRELEAGFGGRIGVAARR--GGRTL-HYRAGERFAMLSTAKALVVAAVLHRAP +CDPGLLDLVVRYGADDLVEHSPVTERHVDAGMTVEALCDAAIRQSDNTAANLLLRQLGGP +DDLTRFARFIGDRVTRLDRWETELNSNLPGDPRDTTTPAAMAADLEALVLGDVLAAEDRE +RLTGWLVGNTTGDARVRAGLP-GWRVGDKTGTGAYGAANDIGVAWPPSGPPLVLAVFTTR +PEEAAEPADEVVAEIARVVAE-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. CB02488 TaxID=1703920 RepID=A0A1Q5N9Y0_9ACTN +--RTERAFRDLERKFDARLGVHTLDTGSGRTV-THRPDERFAYASTCKALLVGAVLDKNS +--LRQMDRLVRYGRDDLVSASPVTERHVATGMTLRELSDAAIRYSDNTAANLLFHELGSP +RALQDALRALGDDVTRCDRYETALSDATPGDLRDTSTPRALATGLRAYVLGNILPADRRA +VLTDLLRRNTTGDNTIRAGVPDHWQVGDKTGTGGYGTRNDIAVIWPPGAAPITLAVLSRR +DAKDAERDDALIAGAAKVALD-- +>[subseq from] L2 beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LF96_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATALSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase AST-1 n=1 Tax=Nocardia brasiliensis TaxID=37326 RepID=A0A379A6I6_9NOCA +---ATADLTALEQQYDAQLGLFAVDTGSGKTL-TNRADQRMPFLSTFKGLAAGALLKAHP +LATGYFDKVVHFTEADLVTYSPVTSTKVAEGMTIAQIADAAITQSDNTAGNLLLRELGGP +QGLTAFLRTLGDQVSRLDRWEPDLNTALPDDERDTTTPAALAADYRALVLGDALGAPERE +QLTKWLKANTTGDKRIRAGVPAGWTTGDKTGTGDYGMANDAAVTWPDGGAPLVLAIQTRK +STKTAEPSNDLVAAATKLVVDK- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Curtobacterium TaxID=257496 RepID=UPI000DA9CB15 +--ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTIKVFIAAAVLDASS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP +HAVERWLRGIGDRTTRVDRVEPNLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPTWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR +ADPGAEPSDALVAAATRTAV--- +>[subseq from] Beta-lactamase n=1 Tax=Lentzea guizhouensis TaxID=1586287 RepID=A0A1B2HAH3_9PSEU +--SITNRLRDLEEQHGARLGVFASDTGSGRTV-LYRSNERFPICSVFKTLAAGAVLRRDQ +-DGSLLGKVIRYTQAEVDKYGPITGKNLANGMTVRALCEATITYSDNAAANFLLRELGGP +SAVTRFCRSIGDPVTRLDRWEPELNSAEPWQELDTTSPRAIGQTYARLTVGHALERPDAR +QLTDWLLANTTGANRLRAGLPGEWRLGDKTGTGSYGTTNDVGITWPPGRRPIVVAVLTTK +PDQKAGADEPLVAKAAGLVADAf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces flavochromogenes TaxID=68199 RepID=UPI000AA1CBB4 +--DLVARLRELEERHSARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTFAVAAVLRDLD +HDGSFLARRIRYTAADVKRWSPRTEENLAHGMTVAELCDATLRFSDNTAANLLLRELGGP +TAVTRFARSIGDRTTRLDRWEPELNSAEPWRETDTSTPRAVGRSYGRLVLGDALPRRDRE +RLTGWMLANTTSGERFRKGLPADWVLADKTGGGRYGGNNDAGVTWPPDGGPIVLTVLSTR +FVEDAAPVDALVADAAALVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Delftia acidovorans TaxID=80866 RepID=A0A2W5HB30_DELAC +-qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ +QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP +QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA +LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTTNDAVIAWPPQSAPLLVTGYLTE +CPADAPQRDAALAAAGKAAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. DvalAA-43 TaxID=1839762 RepID=A0A1C4R2U3_9ACTN +----DGQFKELERSFGARLGVYAVDTGTGREV-AYNDRARFAFASTFKAFAAGAVLRKDS +--VDGLDEVVTYSRDDLVSNSPVSEKHVGTGMNLGALCDAAVRFSDNTAANLLLDRLGGP +RGLDAVLAGIGDDVTRMEHQEPELNQWSPGAMADTSTPRALAGDLRAFVLGDVLGKDERA +QLTKWLRANATGDELIRAGMPKNWVIGDKTGAGGYGTRNDIAVVWRPDAAPIVVAILTNR +HKEDDAYDNALIARAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium guangdongense TaxID=1325090 RepID=UPI00112C9BBD +-----PELEAYERASGGKVGVYAENLATGAKL-SWRADERFVMCSTFKASLAAAVLARVD +RGEEKLDAMIAYGKADLLDYAPAAKENLAAGMSVTDMCKAIVEISDNTCANLLLARIGGP +AALTTFWRSLGDQVSRLDHYEPELNRSPPGDPNDTTTPTAMVGNFRRLVIGDALSAKSRA +QLTEWMVNCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWPKPDAPILIAAYTQG +GTPNAAQLQAVFASVGRMAAQ-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00066E6A77 +----ASDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATMLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. KBS0706 TaxID=2578109 RepID=A0A554UFV9_9MYCO +---AAARLAELERVHGGRLGVAALNLATGARI-GYRADERFLLCSTFKALAAAFVLARVD +RKQERLDRRIVFSRKDLVGKSVLEPRVGRAGATMAELCDAAVTYSDNTAGNLLLASFGGP +VGLTAFLRSLGDEVSRLDRIEPGLNAAGPGDPRDTTTPAAMLETLRKLLFGDALSPASRH +QLAAWLITNKTGDTRLRAGFPAGWLVGDKTGTGGEGSTNDVAVAWPPDRGTVIVTAYCEL +PSQTFEQRNPVVAEIGRIVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TRM43335 TaxID=2569853 RepID=UPI0012BA9570 +------RLIELERKFDARLGVYALATGTGATI-AHRADERFAFCSMFKVPAVAAVLHRNP +--LSHLDTVVRYTEDDLMRHSPVTRRHVDTGMTIRRLCDAAIRYSDGTAGNLLLRELGGP +AHVTAYARGIGDTVTRMDRVEPAITEATPGDPRDTTSPRAFGTGFHRIVLGDALTNDKRA +FLRDLLERNTTGAHRIRAVVPRGWTIANKTGTGDYGTLNDTAIVWPARTAPLVVTIMSGK +AARDAEYDEALIAEAAAYAM--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus hemicellulosilyticus JCM 9152 TaxID=1236971 RepID=W4QIQ0_9BACI +--TVEDTFSQLEEEYDARLGIYALDTGTGKTV-TYRSDERFIYASAHKPLAVGVLLQQKS +--MEELDEHITYSRDDLVNYNPITEHHVDSGLTLKELSDASIRYSDNTAANLIFHAIGGP +EGFKEGLRAIGDNVTEPERIEPDLNDVEPGEIQDTSTPEALAKSLQQFTLGDALSEDKQE +LLIDWLKRNTTGDDLIRAGVPEGWEVGDKTGSGSYGTRNDIGILWPPGRDPIILSVLTSK +EEQDADHDDTLIARATEEVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces clavuligerus TaxID=1901 RepID=UPI0001851576 +-----ADLAALEREHGARLGVYALETGTGAEV-AHRADERFAFCSTFKALAAAAVLHHHP +--IRHLERRVTWTRADVDSISPVTEDHIATGLTVGQLCDAAIRHSDGTAGNLLMRDLGGP +SRLTAYLRGLGDSVSRMDQYEPELNHDPPHDPRDTTTPRAIASDYRKLVLGDALTPDRRA +LLTDWLVRNTTGGRRIRAGVPSGWRVADKTGTGNYGRANDIAVLWPPRSSPLVVAVMSDR +PGFRTPPSERLIAEAAERIV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Nocardioides sp. dk884 TaxID=2662361 RepID=A0A5Q0NS18_9ACTN +----DEAFVALEKRYDARLGVFAIDTHTGETL-AHRADERFAYASTYKALAAAAVLARTE +--ARRWEEVVTYGADDLVTYSPVTEQHVGTGLSLRRIAEAAVRESDNTAGNLLLDELGGP +AGLQRALRGLGDDVTVVARRETALNDTSPGDRRDTSTPRAFAQVLQRYAVGDALRPPARR +TLLRWMRGNATGDTLVRAGVPDGWRVADKSGAAAYGTRNDIAVIEVPGRDPVVMVVFSDR +STADAEYDDALVAEAARVAL--- +>[subseq from] Beta-lactamase n=2 Tax=Mesorhizobium TaxID=68287 RepID=A0A1A5QDV8_RHILI +------KIRRIEAKSGGRLGVACRIAGTGVQF-GYRENELFPICSTFKTLAAAFILHRVD +GGIEQLDRSMEVPHNAVVANSPTTKNHAGGAMTVAQLCEAAVTVSDNGAANLLLASFGGP +PQLTAYLRSIGDTVTRLDRIEPELNESVPGDPRDTTSPLAMIEDYERLALGDSLSQKSRA +QLVDWLVANKTGDDRIRAGLPKRWKCGDKTGTGEHGSTNDAAVIWPTSGNPVLMSLYLTG +TGQSLVKRNATIASVSRALVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura montaniterrae TaxID=1803903 RepID=UPI00124DD692 +--AVTEQLKALEKSRKDRIGAYAVDTGTGRFA-AYREDERFAFASTFKVMACGAVLRKAR +QDPGLMDRVVHYKKSDLVDNSPVTEKHVKTGMTLSALCKAAITQSDNTAGNLLLRQIGGP +AGDTAFLRSLGDRVTRHDRWETDLNLWKPGELRDTTTPRAWAGDLRSLTAGGALVRADRD +RLTGWMKQTVTGDHRIRAGLPKSWTVGDKTGTGGWGTANDIAIAWPPSGAPLIIVITTNR +LAAGAEADEPAVAKTASILAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces durhamensis TaxID=68194 RepID=UPI0007C65FFE +--GAEAELSDLERRHGARLGVYARNLRTGRTV-AHRAGERFAMCSTFKAFAAAAVLRDHG +-DCAPLDKVIHYPPHDIISNSQHTAEHVDTGMTVAELCAAAIRYSDNAAGNLLLREIGGP +AGLTRFFRSLGDQVSRLDRWETDLGSAIPGDLRDTTTPQALGRSFERLTLGRALTGADRE +RLVGWLKGNTTSAARFRAGLPRDWVLADKTGTGDYGSANDIGVAWTTRGTPVLLTVLTAK +GAQHAPADDALVEEAARLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDE0C48 +----EAELAALESRHPGRICVSILDMASGKRI-EHRARERILMCSTFKALAAALVLARID +RGQEKLDRRIRYTKSDLVHGSPATKAHVRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP +KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS +QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI +PAIAADERNGIVAEIGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Y36 TaxID=2035447 RepID=A0A2A6PPE8_9BRAD +------ELESYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGKADLLEYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTLSRLDHNEPELNRSPPGDPRDTTTPMAMAGNLRRLVLGEALTPASRS +LLTEWMVNCKTGANRLRGGLPASWSIGDKTGNNGKDASGDIAVVWSKPETPILVTAYTQG +GTPNAAQIEAAFARIGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. 190mf TaxID=1761798 RepID=UPI00089ED4C4 +---AEPDWAAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKALAVAAVLARVD +AGRETLDRVVSYGAGDLLSYAPVTEACAGTGMSVADLCAATLIWSDNTAANLLLADLGGP +EALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRVLLGTVLSPASRA +RLEAWMVACETGRKRLRAGLPPGWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTE +STASPDTCAAAYAEIGRLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. WAC01526 TaxID=2588709 RepID=UPI0011E023F1 +--TFASAFKKLERKYDARLGVYAVDTDTGREV-AYKDGERFSYNSTFKALAAGAVLRKHS +--PSAMDRVIKYSKDDLVATSPVSEKHVATGMSLSELCDAAVRYSDNTAANLLLEDLGGP +KRLEGVLKGIGDDVTRMEHIEPKLSQWTPGDTRDTTTPRTLAKDLRAFVLGDVLDKGDRK +QLTKWLRTNTTGDEVIRAGMPKGWVVGDKTGAGTYGARDDIAVVWPPGRAPIAVAIMSNR +FKKDADFDNKLIAEAASVVA--- +>[subseq from] Beta-lactamase n=1 Tax=Comamonas testosteroni TaxID=285 RepID=A0A373F8W2_COMTE +----TKELAQLEVQSGGRLGLHMLDTATGLEA-GWRSQERFALCSTFKTLLAAQVLQAAQ +MGQLQLQRSYHYESAEVVPWSPITEKHVGAGMTLQQLCEAAVVVSDNTAANLLLKATGGP +ALLTNWLQTLGDSVTRLDRNEPELNTAIAGDERDTTTPAAMLRTLQKILLGNVLSEPHRA +LLQQWLVASRTGDKRLRAGMPADWKAGGKTGSGDNATANDTLIVWPKGTAPLLVTAYFTG +SKLDATGRDAVLAKAGEVVSRW- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=UPI000344A358 +--TLAQRLAGIERRTGGRLGVTLLD-GSGAVLgGQRQDERFPMCSTFKFVLAAAVLQRVD +RGELSLQRPVQIRAVDMLSHAPVTERHVGGALSVAELCRATMIFSDNPAANLLFPLVGDP +PGLTRFLRELGDPVTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDVLRPASRQ +CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG +AKVDEAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. 8I-2 TaxID=2653136 RepID=A0A653V8P5_9MICO +--ATARAFASLERRYDARLGITAVDTGSGRTL-VHRAGERFAFASTVKVFIAAAVLDASS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTRVDRVEPDLNQATPGDRRDTTTPERFAADLRAVLLGDVLDAADRR +VLRDAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSR +ADAAAEPSDALVAAATRAAV--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas translucens pv. cerealis TaxID=152263 RepID=A0A514E9A6_XANCT +-qTLAQRLAGIERGTGGRLGVTLLD-GSGAVLgGQRQDERFPMCSTFKFVLAAAVLQRVD +RGELSLQQRLPIRAADMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP +PGLTRFLRTFGDAQTRSDRHEPEMNRFAADDPRDTTTPAAMAATLRTLLLGDVLRPVSRQ +RLSEWMIDNRTGDACLRAGLPRGWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG +AKVDDAARDAALKAVAVVVCE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE10127 +----EAELAALESRHPGRICVSILDMASGKRI-EHRARERILMCSTFKALAAALVLARVD +RGQEKLDRRIRYTKSDLVHGSPATKAHLRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP +KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS +QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI +PAIAADERNGIVAEIGRVAA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. VV52 TaxID=2066958 RepID=UPI000C9E1FCE +-----SDFAALEKASGGRLGVTLLNTATGARV-GHRQDERFPMCSTFKFALSATVLHLAD +KGTLSLDRRLPVRQQDMLSHAPVTKRHVGKDLTVRDLCRATMVTSDNPAANLLLGVVGGP +AGVTAFLRGHGDAVTRNDRLEPEMNDFAPGDPRDTTSPAAMAASLQRFVLGDVLSKPSRL +QLADWLIDNETGDARLRAGLSPAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ASVDDAGRNDVLRQVAVI----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5755 TaxID=1519475 RepID=A0A0M8RM41_9ACTN +-----PRLAALERKYDARLGVYALATGTGATV-THRADERFAFCSTFKGLAAAAVLHRHP +--LSYVNTVVTYTEADLMKHSPVTRKHVATGMTIRQLCDAAIRFSDGTAGNLLLREIGGP +GELTAFTRGLGDTVTRMDRIEPAITEATPGDPRDTTSPRAFGTDYRKVVLGDALAADKRA +FLRDLMERNMTGARRIRAAVPRGWTVADKTGTGDYGTLNDIAVVWPAKSPPLLISIMSSK +STKDAAYDQTLIADAAAYVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Comamonas testosteroni TaxID=285 RepID=A0A373FC25_COMTE +---WSHAMAQIEQDAQGRLGVAMLDTGSGLAL-GWRQDERFAMCSTFKLPLAAWVLALVD +QGRERLDARVQYSEAELVEYSPVSGPKAGARLTVGELCAATVSLSDNSAANVLLARHGGP +AALTAWLRSQGDSITRLDRNEPSLNEATVGDERDTTTPLAMLHTMQRLVLGNSLSPSSRA +TLQRWLIETSTGDQRLRAGAP-GWKVGDKTGTSGSGTANDIGVLWPPGGAPVLVSCYLTQ +STARPEQRDAAIAQVARAVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB7835 +----EAQLATLESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD +KGEEKLDRRIHYKKSDLIDYSPATKPNAGENMTVGELCAAAVTLSDNTAANLLLASFGGP +GAITTFCRSIGDEITRLDRTEPTLNYDTPNDERDTTTASAMLENLQRLLFTDVLTPASRS +QLAAWLITNKTGDARLRAGLPKDWLVGDKTGTNGHGNANDIAVLWPTKRAPIIVTAYCEI +PAIAADERNAIIGEIGRIAA--- +>[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000BA40330 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIV------ +----------------------- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase IMI-13 n=1 Tax=Enterobacter asburiae TaxID=61645 RepID=A0A218KGD7_ENTAS +-----DEIKSLETDFNGRIGVYALDTGSGKSF-SYRANERFPLCSSFKGFLAAAVLKGSQ +DNQLNLNQIVNYSTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDEVFRLDRWELDLNTAIPGDERDTSTPAAIGKSLENLALGNILSEREKE +TYQTWLKGNTTGATRIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +NQKEAKHDDKVIAEASRIAID-- +>[subseq from] Beta-lactamase class A/beta-lactamase class A CARB-5 n=1 Tax=Pseudomonas salegens TaxID=1434072 RepID=A0A1H2HJ22_9PSED +-----TALDRVAEQLDARVGFSAYDLETGQRW-EYQANQRFPLSSTFKTLACADLLRRVD +KGEMDSSSKVHFSAADLVTYSPVTEHFAGRQMTLSALCEATLTLSDNTAANLILRALGGP +ASVTAFARFLGDGSTRLDRWETDLNEAQPGDPRDTTTPNAMVNNLHKLLLGDVLSVESRG +QLRNWLERNQVADGLFRAAVPEAWVVADRTGAGGFGSRSITAVMWPPDRQPIIVALYITD +TAASFSERNDAIADIGIAIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2W6G3S0_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPVSRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia veterana TaxID=132249 RepID=UPI00031B1831 +------ELHHLEARLRGRLGLYALDTGTGRTV-EYRADERFPYCSTFKALAAGALLSTLP +--PAELDRHVSYTRADLVPNSPITEPHVEQGLTLREILDAAVRFSDNTAGNLMFAELGGP +QGLQQRLRDIGDATTRMDRTETSLNEAVPGDERDTSTPRALAADLRHYVLDPSVAADDRE +VLTGMLRANTTGGALIRAAVPTDWQVGDKTGAGAYGTRNDVAVVWPPGRAPIVLAVLTTR +DRPDAEYDNAAVARAAAIAV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. JV178 TaxID=858632 RepID=A0A2G9DHK0_9ACTN +-------LRALEERYGARLGVYAHNVRTGETI-RHRADTLFPICSLFKTLAAAAVLRDLD +RDGEVLSRRIHYTAADLLENSDVTRDHLATGMTIAELCNAAIRHSDNTAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRTTDTTSPRAIGRTYARLVLGDTLGRPDRA +LLTHWLLHNQTSNTRLRAGLPSSWAVADKTGGGSYGTNNNVGIAWTEDGTPLVLSLMSRK +FDQDATTENKLIADTAHLL---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=UPI0009A047F0 +---VVRKLRDLERRHGTRLGVFGWNTVTGRTV-LHRANERFPMCSTSKAMAIGAVLRDLD +HDGTFLSKVIHYTQQDIDRAAPVTGQNLAHGMSVADLCGAAVSYSDNTAMNLLLTELGGP +AAVTRFCRSLGDTVTRLDRCEPELNSAEPWRVTDTTTPRAIGRTYARLALGNARDTADRT +RLTGWLVANTTGGKRLRAGLPEGWTVGDKTGTGRYGTTNDVGIVWPPGRGPIVMAVLSTR +PEPDAEMDDAVIAETAALL---- +>[subseq from] Beta-lactamase n=1 Tax=Kitasatospora viridis TaxID=281105 RepID=A0A561SEL7_9ACTN +--SADAAFQQLEQHYGARLGVYVLDTGSGREL-RYRADERFAFASTAKTLSAGALLRTAS +--EAELDKVVRYSQQDLLAWAPVTSQHLATGMTVRDLLAAALDHSDNTAANLVTAELGGP +AAVQQTVRALGDTTTNVDRTEPTLNEATPGDPRDTSTPRQLATDLRTYALGDALPADRRT +QFTDWLVANTTGGPYIRAGVPAGWKVGDKTGNGDYGTRNDIAVVWPAGGAPLVVALLSDR +GKADAKSDDDLLAQATKTAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-1347 TaxID=1476877 RepID=UPI0004C55A06 +----ARAFKKLERKFDARLGVYALDTGTGREV-AYNDSRRFAYNSTFKALAAAEILRKYA +--PDGLEQVVKYSKDDLIANSPITEKHVDTGMTLRALCDAAVRYSDNTAANLMFDKLGGP +KGLDAALERIGDDVTRMDRVEPFLSRWVPGEKRDTSTPRALAKDLRAYVLGDVLAEPERA +QLATWLKTNTTGDHVIKAGVPKNWVVGDKTGTGSYGARNDIAVVWRPDAAPLVVAILSHR +GDKDAAPDDKLIAEAASVVA--- +>[subseq from] class A beta-lactamase n=3 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDBE850 +-hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD +KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP +PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA +QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDIAVAWSPNRGAIVVATYCEI +PTISADERNAVVAEVGRL----- +>[subseq from] class A beta-lactamase n=1 Tax=Halobacillus sp. Marseille-P3879 TaxID=2045014 RepID=UPI000C7A0826 +--DTNQKFAELEDKFDAQIGIYAIDMGTDQTI-EYRPEERFAFTSTYKALAAGTLLQQKS +--TAELKEVITYTEDDLVPYSPVTKENADEGMTLLELSEAAVRTSDNTAGNLLFEALGGP +EKFEMALRQIGDNVIEADRYEPELNEFTPGDSRDTSTPRALAASLQTFAVDDLLSNDKRK +LLVDWMRGNATGDTLIRAGAPEDWEVVDKSGAGSFGTRNDIAVVWPPNRDPIVMAIMSRH +DMEDAEYDDALIEQSAEVIFDIf +>[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. OV329 TaxID=1882825 RepID=A0A1I4YTM8_9BURK +--QAAAALAEIERRSGGSLGLHAMDTGSGRTL-SHRGEERFAMASTFKLLLAAAVLHRND +QAAGVLDERLPVRKTDLIAHSPITSKHLQAGITAREACEATVQVSDNAAANLLLPLVGGP +EGLTTFVRECGDGVTRLDRTEPTLNTNLPGDLRDTTTPAAMARTTARLLTGDVLSGPSRT +QLKSWLEGASTGMARLRAGLPKDWRTGDKTGTGANGAANDVAVTWAPGRAPIVLAVYLNG +STQPPAVLDATHAQAAAVVAAFf +>[subseq from] Beta-lactamase n=1 Tax=Kosakonia sp. WCHEs120001 TaxID=2529380 RepID=A0A4R0GZD4_9ENTR +------AVARLEEHLGARIGIAVVDTASGETV-SYRGDERFPLNSTHKALLCGAVLSKVD +KGELALNETTQFSQSELVPYSPVTSQFVAPSMSWRQLCSAAVSESDNTAANLVAKKLGGP +AAVTRFFADSGDSVTRLDRAEPELNSAVPGDLRDTTTPLAVSHTLQKLALGEVLTPRSRA +QLVQWIKEDKVADALLRSTLPKGWVIGDKTGAGGYGSRSIISIVWPKKGAPRIVSIYITD +TKATIAQSNDAIARIGKAIFS-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NEAU-SSA 1 TaxID=2315329 RepID=A0A505D5T3_9ACTN +----TGELKELERKFDARLGVYAIDTGTGREL-AYRDGERFGYHSTFKALAAGAVLRKYK +--LTGMNEVIKYSKDDLVHHSPITEKHVETGMTLRELCDAAVRYSDNTAANLLFEALGGP +KALEAELRKLGDDVTVMERIEPGLSDWVPGEKRDSTTPRALAEGLRAYVLGDVLRKPERA +QLTKWLKTNKTGDELIRAGVPEGWVVGDKTGSGNYAGRNDIAVVWRPGAAPVVMAIMSNR +GKAEDTYDNKLIAEAATVVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000CFD8B78 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGK----------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces alboviridis TaxID=67269 RepID=UPI000516B9C5 +---TDRAFAGLERKFDARLGVYAVDTGDGRIV-AHRPDERFAYASTCKALLAGAVLAKKS +--LPQMERLVRYGEEEIISNSPITEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP +RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYVLGAALPAEKQA +VLADWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVRPPGGAPIALAVLSRR +DTKDAEPQDALIAGAAKVALEAf +>[subseq from] Beta-lactamase n=1 Tax=Amantichitinum ursilacus TaxID=857265 RepID=A0A0N1JTG1_9NEIS +--DLAAAMAALEHASDIRIGVSAFDTGNGKRF-DWRADERFAFCSTFKFMLAAAVLNERK +RQPRVLQERLLYTHKQLPAHSPITEKHVADGMIVSDLCKAAIEYSDNGAANALLRYLGGP +AKVTAFARKTGNASFRLDRMEPELNTSIPGDVRDTVTPADMARSLQTLVLGEALPEHERG +LLSEWLKGNTTGDKRIRAGVPAGWMVGDKTGTGAYGSTNDIAVLWPGNGAPICMAIYVGS +KHKDADPPETVLAEATRIALK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinopolyspora saharensis TaxID=995062 RepID=A0A1H0ZTD6_9ACTN +--EAKDRFAGLEQRFDARLGVYAVDTATGEEV-THRADERFAHASTYKALSAGVVLRRNS +--IGGLNRRIHYSRSDLVTYSPITKKHVDTGMTLRAVLDAAIRYSDNTAANLLFREIGGP +AALQAALRGIGDTTIHVDRTEPELNRRAPDDIRDTSTPRAMAETLRKFTVGDVLAPDKRA +ILNEMLRTAKLTGDLVRAGVPSGWEVGDKSGAAEYGTRNDIAVIRPPGRAPVVLAVMSDR +QSRDAEYDDALIAQAARQVVD-- +>[subseq from] Beta lactamase n=1 Tax=Xanthomonas translucens pv. graminis TaxID=134874 RepID=A0A1M4IEE6_XANCT +-qTLAQRLAGIEWRTGGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFVLTAAVLQRVD +RGELSLQQRLPIRAADMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP +PGLTRFLRTLGDAQTRSDRHEPEMNRFAADDPRDTTTPAAMAATLRTLLLGDALQPASRQ +QLSAWMLDNRTGDACLRAGLPPGWKIGDKTGSNGTDTRNDIAIVWPPGRMPLLLTAYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_018 TaxID=2175638 RepID=UPI000DA6DF7F +---TARVFAALEQRYDARLGVVAVDTGNGRTI-AHRAGERFAFASTIKVFIAAAVLDASS +--DADLAAVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP +DAVERWLRGVGDRTTHVDRAEPDLNEATPGDRRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNMTGDATIRAGVDPSWRVADKTGTASYGVRNDIAIVTPPGRAPIVLVVMTSR +ADPDAEPSDALVAAATRAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI001296F596 +-hALEARLAELKRRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD +KGVEKLDRRIVFSKEVLVYFSPLTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP +PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA +QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDIAVAWSPNRGAIVVATYCEI +PTISADERNAVVAEVGRLVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albofaciens TaxID=66866 RepID=UPI001239A2E3 +----HRRLAELERKYDARLGVYALATGTGATV-AHRADERFAFCSTFKGLAAAAVLHRHP +--LSHLDTIVTYTEADLMKHAPITRKHVTSGMTVGQVCDAAIRFSDGTAGNLLLREIGGP +GQLTAFTRSLGDTVTRMDRTEPAITEATPGDPRDTSSPRAFGTDYQKVVLGNVLAADKRA +FLRDLLERNETGARRIRAAVPRGWTVADKTGTGDYGTLNDIAVVWPAKSPPLLISIMSSK +SAEDAAYDQALIAEAAEYVVH-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces sp. S5 TaxID=1456735 RepID=UPI000EF8727F +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALDPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAVRDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=2 Tax=Nitratireductor TaxID=245876 RepID=K2M8G9_9RHIZ +--ALLKRMDEVEKRVGGRLGAVIVDLETGRRW-SRRADERFPMNSTFKAFACAGVLARVD +AGEEDLGRRIAFGMRDLIHHSPVTEKRAGTRLTLAELCEATIGWSDNTAGNLVLDAIGGP +PGFTAFMRSLGDTRTRIDRREPELTQNTPGDPRDTTTPNAIVATLQALLLGDALSSASRG +RLERWMVEGKVTGPLLRSGLPEGWRIADKSGAGRRGSRGIVAVIWPPERQPVVAAIYMAE +CACSMAQRNAAIAAIAPALF--- +>[subseq from] Beta-lactamase n=1 Tax=Nitrincola tibetensis TaxID=2219697 RepID=A0A364NQZ1_9GAMM +--ALMTELQRIENVLDARIGFSAYDSETGVRW-EYNADQRFAMSSTFKTLACAALLQRVD +SNEEQLERKVSFSKSDLVTYSPITEQHADSRMSLFELCEATLTTSDNTAANLILQAIGGP +EVVTEFARGIGDNVTRLDRWETELNQATPNDDRDTTTPNAMVGNLKGLLLGDVLSPNSKS +QLREWLVGNKVADGLFRASMPAEWVIADRTGAGGFGSRAITAVIWPPERLPILVAFYITE +TTASFEDRNTAIAELGSVI---- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A317BTB9_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDECFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Kibdelosporangium sp. MJ126-NF4 TaxID=703222 RepID=UPI0005827EC1 +-----AALVEVERKFDARLGMFALNTATGVTV-THRADERFAFCSTFKGLAAAAVLHRNP +--MSHLDTIVRYGKGDLLKSAVITSQHVTTGMTIRDLCDAAIRYSDGTAGNLLLRELGGP +QQLTEYLRGLGDSVTRMDRTEPAIVEATPGDPRDTASPRALGTDYQKIVLGDVLPEDKRA +FLRDLLERNTTGAQRIRAGLPPDWRVADKTGTGDYGTINDIAVVWPPGAAPLVIAVMSSK +AAKDAKYDQALIAQAASHA---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6ALC6_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKA---------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus caseinilyticus TaxID=1503961 RepID=A0A1H3SLF4_9BACI +---ADEIFSKLEEEYDARLGIYALDTGTGETV-AYRADERFIYASTHKPLAVGVLLQQKS +--LEDLDQLITYSKDDLVNYNPITEKHVDSGMTLKELSDASIRYSDNTAANLIFQEIGGP +EGLKAGLRAIGDTVTEPARIEPDLNDVEPGEIQDTSTPEALAKSLQAFTLGDSLPADKQE +LMIDWLKRNTTGDDLIRSGVPEGWEVGDKTGSGSYGTRNDIAVIWPPEKEPVILAVLSSK +DNRDGEHSDELIARATEEVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseus TaxID=1911 RepID=UPI00056AD7C1 +----TGRLRALEEHYGARLGVYAHNVRTGKTI-RHRADTLFPICSLFKTLAAAAVLRDLD +RDGEVLARRIHYTAADLLDNSDVTKNHLATGMTIAELCDAAIRHSDNTAGNLLLRELGGP +TAITSFARSLGDPVTRLDRWETELNSGEPWRITDTTTPHAIGRTYARLVLGDALTRPDRA +LLTHWLLHNQTSNTRLRAGLPSSWTVADKTGGGSYATNNNAGIAWTQDGTPLILSIMSRK +FDQDATPENKLIADTAVVLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3G1QBL9_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAV----------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces showdoensis TaxID=68268 RepID=A0A2P2GPS3_9ACTN +------DFQRLERAYGARLGVYAVDTGSGREV-LHNHTERFAYASTFKALAAAAVLRSHS +--PSGMGKVIRYSGEQPVDHSPVTEKHVETGMTLHELCDAAVRHSDNTAANLLFDALGGP +KGLAAALREVGDTTTVVERREPELNQWAPGATRDTTTPRAIAGDLRAFVLGDALGPAERA +QLTTWLRTNTTGDELIRAGVPAGWVVGDKSGAGDYGVRNDIAVLWPPDAAPIVMAIMSNR +GTEEADDDNGLIARAASVAV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ADI93-02 TaxID=1522757 RepID=A0A3N6F097_9ACTN +----EQAFGELEQKFDARVGVYAVDTGSGLTV-THRPDERFAYASTCKALLAGALLKTYT +--LPQLDRRVRYGPGDLVANSPVTEQHVDTGLTVRELCDAAVRHSDNAAANLLFQELGGP +GGLRDALVALGDRTTRCDRIEPDLSEAAPGDVRDTSTPRALAADLRAYALGSALGTDARA +VLNDWLERNTTGDALIRAGAPAGWVVGDKTGTGGYGTRNDIAVVRPPGSAPIVLAVLSRR +DARDAEPQDALVAGAARVALDAf +>[subseq from] Beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=A0A2P1TJY4_CLOBO +--QYNSAFSQLESDYDVKLGIYAFDTEMNKEV-AYHADDRFAYCSTFKALAAGAVLKQDS +--LDELKQVVKYKKEDVLSYAPIAKDNVDKGMTIEEICNAAVRFSDNTAANLLFNHIGGP +SGFKSALNQLGDNVTQPARIEPELNEAIPGDIRDTSTPRQLATDLQAYTTGNILTDDKKR +ILIDWMTGNATGNTLIRAGAPDNWVVADKSGTGPYGTRNDIAIVMPPNKKPIIIAILSTH +HTKEAKYDDKLIAQASKIVFDYf +>[subseq from] class A beta-lactamase n=1 Tax=Aquabacter cavernae TaxID=2496029 RepID=UPI000F8E42B0 +--QAEHACAAIEARTGGRLGVAVLDGTGAPRI-LHRAEERFPFCSTFKFLVAGAVLKRVD +EGKERLDRRIAYGTDDIIQHSPVTKANLGKGMSVADLCAATVTLSDNAAANLLLATLGGP +KGLTAMLRAIGDTVTRNDRWETALNSAIPGDPRDTTSPLAMARDIHALVVGDVLSPPSRT +LLATWLYDCKTGDDRLRAGLP-GWRVGDKTGTGGTGTVNDVGIAVPPGTRPIILSVYLTQ +SRLDLAGSNAAIAEVAALAA--- +>[subseq from] class A beta-lactamase n=2 Tax=Bradyrhizobium japonicum TaxID=375 RepID=UPI000419A075 +------ELESYERETGGRIGVYAENLATGAKL-AWRADEHFVMCSTFKASLAACVLARAD +RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARVGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVVGEALSPASRT +QLTEWMVGCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPKNKVPILIAAYTQG +GRPNAAQIEAVFARVGRMVAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinomycetospora succinea TaxID=663603 RepID=A0A4V3DB40_9PSEU +------ALAGLEQRSGRRIRLLALDTGTGRAV-GHRADERALMCSTAKVLIAAAVLRRAA +TEPGLLDRTIRYSRADLLDYAPTTERFVDTGMTVAALCEAALVVSDNTAANLLSALLGGP +AATTAFVRTLGDTTTRLDRLEPELNETAPGDERDTTTPAAMVADLRALVLGDALDPAGRD +RLTGWMVGAVTGTEQIRAGLPRDWRVGDKTGSGAQGENNDVAVAWPPGRAPWVIAVFTTP +TDPASTNGRATIADATRIAT--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-24085 TaxID=1709476 RepID=UPI0007C6FD31 +---VTARLRALEERYDARLGVFAHRPSTGRSV-RYRADERFPMCSVFKTLAAAAVLRDLD +RHGEVLARRIHYTEDDLVIGSDQTAAHLAEGMTIAGLAEVAITYSDNTAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWEPELNTAEPWRLTDTTSPYAVGRTYGRLVLGDALNRRDRE +LLTHWLLHNTTSVNRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTDTGDPIVLSVLSTM +PAPDAVRDDALVADAAAVVA--- +>[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium meliloti (strain SM11) TaxID=707241 RepID=F7XDI1_SINMM +-hALEARLAELERRHGGRVGVAALNLSTGVRV-GHRADERFLMCSTFKALASAMVLARVD +KGVEKLDRRIGFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP +PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRPSRA +QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDTAVAWSPNRGAIVVATYCEI +PTISADERNAVVAEVGRIVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM4349 TaxID=1040988 RepID=UPI00047772E5 +--DAQPELETYERESGGRIGVYAENLATGARL-AWRADERFVMCSTFKASLAACVLARVD +RGEDQLAAMIPYGKADLLEYAPVAKQNIAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTASRLDHNEPELNRSPPGDPRDTTTPAAMAGNLRRLLTGEALSATSRA +QLTEWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKDTAPILIAAYTQG +GTPSAAQIETVFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces tsukubensis (strain DSM 42081 / NBRC 108919 / NRRL 18488 / 9993) TaxID=1114943 RepID=I2N3E8_STRT9 +----GRAFAALEKEFAARLGVFAVDTGTGRTV-LHRPDERFAYASTCKAFIAAAMLRKFS +--LREMQRRVTYGPEVLQPHSPITERNVGKDMTLSELCDATVRYSDNAAANLLFDELGGP +RGLQTELRSVGDRVTRCDRYEVELSDAVPGDPRDTSTARALATDLRTYVLGNALPPEKRA +VLTDWLKRNTTGDNVIRAGTPDGWQVGDKTGTGGYGTRNDIAIVWRPDAAPIAIAVLSRK +DVKGAEHQDALIARAAEVALNAf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2W6RB90_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLP----------GGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2U4H654_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAAILQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA +GAISNEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia endophytica TaxID=401976 RepID=A0A4V2PIW8_9PSEU +-----AELAGIESRFGGRLGLYALDTGTGRAV-GHRADERFLMCSTTKVPLIALVLRRSV +EDTGLLDRRIRWTRDDLLEYAPVTTPNLATGMTVAELCAAAVTVSDNTAANLLFAQVGGP +QAVTAFVRGLGDPLSRFDRVEPALNDTAPGDGRDTTTPARFAETLRLLTLGDALPPPQRD +RLVGWMDAATTGAAQIRAGVPAGWRVGDKTGSGNRGESNDVGVVSAPGRAPIVVTVFTAP +SDPDSTAGKPTIAAATRAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_003 TaxID=2175637 RepID=UPI000D9F07ED +---TARVFAALEQRYDARLGVVAVDTGNGRTI-AHRAGERFAFASTIKVFIAAAVLDASS +--DADLAAVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP +DAVERWLRGVGDRTTHVDRVEPDLNEATPGDRRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNMTGDATIRAGVDPSWRVADKTGTASYGVRNDIAIVTPPGRAPIVLVVMTSR +ADPDAEPSDALVAAATRAAV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SAT1 TaxID=1849967 RepID=A0A1A9J530_9ACTN +---ATDALRALEERYSARLGVHARNTRTGQSV-AYRAGERFALCSTFKVFAAGAVLRDHA +-SSAPLDKVVRYPDRDILLNSPVTQQHVGSGMTVGELCAAAIRHSDNCAGNLLLRELGGP +AGLTAFFRSLGDRVSRLDRWEPDLNSAGPGELRDSTTPQALGASLERLTVGDELSGAARE +QLLTWLKGNTTSARRFRAGLPKDWVVGDKTGTGDYASANDIGVAWTTRGTPLVLVVLTSR +DAPDAAVDEGLIADAAAVLAD-- +>[subseq from] Beta-lactamase n=2 Tax=Saliterribacillus persicus TaxID=930114 RepID=A0A368XBF0_9BACI +---TSSGFEELEKEYDAKLGVYAFNTGNNQSI-SYRADERFGYTSTHKALAVGALLKKKS +--SDDLDEKINFTEEDLVNYNPVTEKYVDTGMTLKELSDASLRYSDNTAGNLILEAIGGP +KGFKDVLREIGDDVTEPARIEPELNNVEPGETKDTSTPKALAESLQAFTLGDVLSEEKQK +LLNDWLKRNTTGDNLIREGVPEGWIVGDKTGAGPYGTRNDIAVIWPPDDSPIVLAILSRR +EKADAEYDDELIAKATKVAIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE1DDE1 +----EAELAALESRHPGRICVSILDMASGKRI-EHRAHERILMCSTFKALAAALVLARID +RGQEKLDRRIRYTKSDLVDGSPATKAHVRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP +KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS +QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI +PAIAAGERNGIVAEIGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB03911 TaxID=1804758 RepID=A0A1Q4X2A1_9ACTN +---ITDRLRALEQAHGARLGVFVWDTVTGRTV-LHRADELFPMCSTFKTIAVAAVLRDLD +RDGAFLAHRIRYTERDVTAYAPVTGLNLADGMTVADLCAAAVDHSDNAAANLLLRRLGGP +GAVTRFCRSVGDDVTRLDRWEPELNSAEPGRVTDTSSPRAIGRTYARLTLGGALRPGDAR +RLTGWLLGNTTGTNRLRAGLPADWTVADKTGTGAYGSTNDVGIVRPPGRGPVVMAVLSTK +DEAAAPADEPLVAGAAALLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ScaeMP-6W TaxID=1839779 RepID=A0A1C4NYX3_9ACTN +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALDPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAVRDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Pantoea latae TaxID=1964541 RepID=A0A1V9DKL4_9GAMM +---LAAVAQQEEQTLKARIGIAVIDTGTSHVA-SYRGNERFPLNSTHKALLCGMLLNEQE +KGKLRLTERTQFDRAALVTYSPVSEKFVAPAMSLQQLCSAAISYSDNTAANLIAEKLGGP +AAVTRFFAHLGDKVTRLDRHEPELNSAIPGDVRDTTTPLAISETLRKLTLGEALTPVSRA +QLLQWMHDDKVADALLRSVLPAGWRIADKTGAGEYGSRSIVSVVWPENGKPLIVSVYVTQ +TEATLAQSNAAIARIGKAIFA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. LUP30 TaxID=1890285 RepID=UPI000851FCF8 +---VTARLRDLEARHGARLGVFACNVRTRRQV-RHRADELFPVCSLFKTLAVAAVLRDLP +--SSAPDRRIHYTADDLVENSEITKDHVADGMTIAELSAAAIQHSDNTAGNLLLRELGGP +AAVTRFARSVGDRVTRLDRWEPELNSAEPGRITDTTSPYAIARTYARLVLGDALSAPDRR +RLTDWMLGTVTSANRFRAGLPATWTIADKTGGGSYGANNDAGIAWTPDGAPVVLAVQLTK +PDREAPYDHALIVETAGVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID4956 TaxID=2690290 RepID=UPI00136F17A3 +------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDHRP +--GARLDERIPYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAGNLL-RDIGGP +RGLTAYARRLGDRVTRLDHTEPELNGNPPGDPRDTTTPRAIAADYRALALGDALPAAGRT +LLTDWLVRNTTGDRRIRAAAPRGWRVGDKTGGGEYGRGNDVAVLWPGGRPPLVLSVLTER +PGRAATPSDELVAEAARRVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Paenibacillus terrae TaxID=159743 RepID=G7VP75_PAETH +-----VVFKQLEIKFDARLGVYVIDTGTGKEV-AYRADKRFAYASTYKALAAGAVLQQKS +--NDELGKVINFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP +EGFEKAMRDNGDTVVMANRYETELNEAIPGDHCDTSTPNALANSLKVLTIDDSMPNDKQE +LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPYREPIIIAVMSSR +DTEDAEYNNALIAEAAKAAFK-- +>[subseq from] class A beta-lactamase n=1 Tax=Franconibacter helveticus TaxID=357240 RepID=UPI00069DA441 +--ALTAAAQQEEKTLNARIGVTVLDTVTGKTL-SYRGDERFPLNSTHKPLLCGALLKQAQ +EKKIRLTDSVLFDKSQLVDYSPVTEKHVSPQMNWLQLCSAAVSYSDNTAANLISQKAGGP +QAITAFVRASGDNITRLDRFEPELNEARPGDERDTTTPDAISHTLQKLLLGDVLSEASRQ +QLTRWMAEDKVADALLRKSLPKGWKIADKTGAGGYGSRSIISMVWPEKGAPMVVAIYITR +TEASLTQSNDAIARLGGVIF--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces qinglanensis TaxID=943816 RepID=A0A1H9R4Z9_9ACTN +-qQAAAAFRKLERTYDARLGVYAVDTGTGREI-SFHAGERFAYASTHKAFTAAAVLDKRS +--VNGLDKVITYRKEDLLPHSPVTSEHVEEGMTLRALCAAALRQSDNAADNLLLRELGGP +EALDAFLEKLGDDVTNVNRYEPELNEATPGDDRDTTTPRAWTADLRAVALGDGLSKKERA +RLDTWMRNSPTGKTLIRAGVPEEWRVSDKSGGGHYATRSDIAVVRPPGRAPLVVTVMSKR +TEQDAEYDDRLVAEAASVVADE- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces badius TaxID=1941 RepID=BLAC_STRBA +------DFKKLEREFDARLGVYAIDTGTGREV-THNDRARFAYHSTFKALQAAVVLSTYS +--LDGLDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDRAAGP +KGLDASLEKLGDDITRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA +QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPDDELIAEAASVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. HMWF029 TaxID=2056863 RepID=A0A2R7MJ63_9BURK +--AWNDALVTIERSAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD +QGKEQLDSRVHYAATEVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDGTTRLDRTEPALNEAAVGDPRDTTTPLAMLHTLQKLVLGDALSIPSRA +WLQRWLAETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVMWPPGGAPVLVTCYLTR +SAAAPEQRDAAIAQVARAVVA-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI000BAE1609 +--DAERRLAGLERASGARLGVYAYETGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLAAGMTVEELCKVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRATDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI000BB61ED5 +--DAERRLAGLERASGARLGVYAYETGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLAAGMTVEELCKVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRATDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura madurae TaxID=1993 RepID=UPI000D982E9E +--EVTERIKRLEAARHTRIGAFAIDSGTGRFV-GHRADESFPFASTFKAMACGAVLRKAR +QAPGLLDKVIHYTKDDLVEYSPVTEQHVDTGMTVADLCHAAITQSDNTAGNLVLRQIGGP +AGLTAFLRTLGDRVSRSDRWETALNDWRPGEKRDTTAPRPWANDLRALTTGDALVPADRR +RLIGWMKATVTGDKRIRAGLPKSWTVGDKTGTAGYGNANDIAIAYPKSGAPLIIVITTTR +PGAEDEADETSIARTATILAN-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. CNPSo 3426 TaxID=2560054 RepID=A0A4Y9P9N6_9BRAD +----PAELESYERESGGRVGLYAENLATGAKL-SWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGKADLLEYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSIDDNTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVVGDALSPASRA +LLTEWMVNCKTGANRLRGGLPASWTIGDKTGNNGKDAAGDIAVVWPKPDTPILITAYVQG +GAPNAAQIEAAFARIGRTVA--- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura madurae TaxID=1993 RepID=A0A1I5CVJ3_9ACTN +--EVTERIKRLEAARHTRIGAFAIDSGTGRFV-GHRADESFPFASTFKAMACGAVLRKAR +QAPGLLDKVIHYTKDDLVEYSPVTEQHVDTGMTVADLCHAAITQSDNTAGNLVLRQIGGP +AGLTAFLRTLGDRVSRSDRWETALNDWRPGEKRDTTAPRPWANDLRALTTGDALVPADRR +RLIGWMKATVTGDKRIRAGLPKSWTVGDKTGTAGYGNANDIAIAYPKSGAPLIIVITTTR +PGAEDEADETSIARTATILAN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces tsukubensis TaxID=83656 RepID=A0A5H2UPA5_9ACTN +----GRAFAALEKEFAARLGVFAVDTGTGRTV-LHRPDERFAYASTCKAFIAAAMLRKFS +--LREMQRRVTYGPEVLQPHSPITERNVGKDMTLSELCDATVRYSDNAAANLLFDELGGP +RGLQTELRSVGDRVTRCDRYEVELSDAVPGDPRDTSTARALATDLRTYVLGNALPPEKRA +VLTDWLKRNTTGDNVIRAGTPDGWQVGDKTGTGGYGTRNDIAIVWRPDAAPIAIAVLSRK +DVKGAEHQDALIARAAEVALNAf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=A0A2A2UAL0_9ACTN +--DAERRLAGLERASGARLGVYAYETGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLAAGMTVEELCKVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRATDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=UPI00099712FE +---AVRKLRDLERRHGTRLGVFGWNTVTGRTV-LHQANERFPLCSTSKTMAIGAVLRDLD +HDGTFLSKVIHYTQQDIDRAAPVTGQNLAHGMTVADLCGAAVSYSDNTAMNLLLAELGGP +AAVTRFCRSLGDTVTRLDRCEPELNSAEPWRVTDTTTPRAIGKTYARLALGNALDRADRT +RLTGWLLANTTGGKRLRAGLPEGWTVGDKTGTGRYGTTNDVGIAWPPGQGPIVMAVLSTR +PEPDAEADDAVIAETAALL---- +>[subseq from] Beta-lactamase n=1 Tax=Azoarcus sp. KH32C TaxID=748247 RepID=H0Q498_9RHOO +-eAIQARLRELETAAQGRLGIHIFDSATGQEY-GYRSDERFMMLSSFKLLASALVLHRVD +VGQESLDRRIAYTKDDLVPWSPITEKHADGRMTLGELCEATITTSDNTAANLILASYGGP +PALTAYARLLGDGITRLDRFEPQLNEGHADKLLDTTTPRAMLSTMQMLVLGDSLSAASRL +RMQQWLLANTTGGKRLKAGLPGDWRIGDKTGTNGT-AANDIGVIWPANRAPILVAAYLAE +SEAASHERDAALAAVGTLI---- +>[subseq from] class A beta-lactamase n=1 Tax=Steroidobacter agariperforans TaxID=268404 RepID=UPI00101C47CE +----VERLTAIRSRIGGRLGAYVLDTHTGRRF-GLDYDERFAMASTFKWLLAAAVLAKVE +RAELRLEQRVSFAEKDLLAHAPVTSKHLRQSLTLRELCAAVVEVSDNTAANLLLRLIEGP +EGLTKFARASGDEMTRLDRTELALNSNLPGDPRDTTTPRAMVGSMERVLLGTVLSEPSRQ +ILIQWMINSSTGLQRIRAGLPAHWKVGDKTGTGASGAVNDLAMVWPPGRKPILMAVYMSE +STETVETLSAAHAQVAAEVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Diaminobutyricimonas aerilata TaxID=1162967 RepID=A0A2M9CHK2_9MICO +---IASAMAALEQQYGARLGVYAIDTGSGAEA-AHRADERFAFASTIKVLAAGALLATRS +--DEELDQPVPVP-SRLEYWSPITEQHAGGTMTAREVAAAAASYSDNTAANLLFDLLGGP +AGLEAELREVGDTTIEVERTEPGLNEATPGDPRDTTTPRAFAATLRAYVLGDALDDTDRA +QLVEWMRGNTTGDALIRAGVPAGWTVGDRTGNAAYGTRNDVAVLWPDDGEPIVLVIMSSK +NAQDAEHDDALIADATRAVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus methanolicus TaxID=1471 RepID=UPI0012484B70 +--STTEQFKQLEEEFAARLGVYVIDTETNRTI-TYRADERFAYTSTFKPFAAAFILQKST +--ISELNKLKTFTTNDLVTYSPITEKHVQTGMNLLEISEAAIQYSDNTAGNLLLEELEGP +KELQQALRKIGDQTTSVDRYETELNEATPGDSRDTSTPRALAKNLQYVGLDEFLSESKKD +IFQDWLKGNTTGDSLIRAGVPKDWVVGDKSGAGGYGTRNDIAIVWPPERKPIIMVIMSSK +DEVEATYNDELIANTAKVIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. YC419 TaxID=1775131 RepID=UPI0013E9DC12 +---FTGELKELESKFDARLGVYAIDTGTGREV-AYRDGERFGYHSTFKALEAGAVLRKYS +--LNGMNKVIKYSSDDLVANSPITEKHVESGMTLRELCDAAVRYSDNTAANLLFDALGGP +KGLEADLRKLGDKVTLMERIEPHLSDWVPGETRDTTTPRALAKDLRAYVLGDVLRKRERA +QLATWLKTNTTGNEVIRAGVPKGWVVGDKTGSGGYGARNDIAVVWPPDSAPIVMAILTNR +GKAEDVHDNKLIAEAASVVAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Tamaricihabitans halophyticus TaxID=1262583 RepID=A0A4R2R275_9PSEU +------ELSTLESENGRRIGVYARHTGTGETV-AHRADERFLMCSTAKLLAASAILKQHE +QQPDLLDKVIHYDREVLMPYSEITEQHVDKGMTVAELAAASITHSDNAAMNLLLDELGGP +SVVTDFVRDLGDEVTRLDRIEPHLNVSAPGDERDTTTPERIGSDLRALALGDALAEQGRA +RLVRWLRGNTTGDKSIKAGLPRDWQVGDKTGSGNNGEVNDVAVAWPPDGDPLIIAVYTAP +DGAERDNGYETVAAAAKIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Pantoea sp. YU22 TaxID=2497684 RepID=A0A432B719_9GAMM +---LATVAKQEEQALKARIGIAVIDTATGSVT-RYRGDERFPLNSTHKALLCGALLSQQD +KGRLMLSERTQFDRAALVTWSPVTEKSVAPAMSWQQLCHAAIAYSDNTAANLIAKKLGGQ +AAVTRFFADLGDKVTRLDRFEPELNSAIPGDMRDTTTPVAVSETLQKLTLGEALKPASRA +QLVQWMRDDRVAGALLRSVLPAGWSIADKTGAGEYGSRSIISVVWPENGKPLIVAIYVTQ +TEATLAQSNAAIARIGKAIFA-- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. EGI 650086 TaxID=1840409 RepID=UPI00131D14D1 +--AARAELSALEARFGGRLGVYAVDTGSGAAV-GHRADERFLLCSTLKTLVVSAILRSHQ +RQPGLLDRVIHYDRAQLLSHAPVTSRHVADGMTVAALCEAAITQSDNTAANLLFQVLGGP +PAVTDFARSLGDPLTRADRTEPELNVSAPGDERDTSTPARMAADLRALALGDALDPAGRE +LLGGWLRANVTGGKSIRAGLPAGWPVGDKTGSGAQGEVNDVAVVWPPGRAPLVIAVYTAP +ADPKATTGYATVAGATTIAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CB03911 TaxID=1804758 RepID=UPI00093BEA6F +---ITDRLRALEQAHGARLGVFVWDTVTGRTV-LHRADELFPMCSTFKTIAVAAVLRDLD +RDGAFLAHRIRYTERDVTAYAPVTGLNLADGMTVADLCAAAVDHSDNAAANLLLRRLGGP +GAVTRFCRSVGDDVTRLDRWEPELNSAEPGRVTDTSSPRAIGRTYARLTLGGALRPGDAR +RLTGWLLGNTTGTNRLRAGLPADWTVADKTGTGAYGSTNDVGIVRPPGRGPVVMAVLSTK +DEAAAPADEPLVAGAAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Phytoactinopolyspora sp. HAJB-30 TaxID=2715536 RepID=UPI00140B54BF +-eDLTEQFEELEDGYDARLGVYALDTGTGQEI-TYRPDERFAYASTFKILLCAVVLQQNS +--VDDLERVITYTEDDLQAHAPVTSEHLDTGLTIRELCDATTKYGDNTAANLLLDEVGGP +EGLGDALREIGDDTISVDRYAPELSDAVPGDTRDTTTPRALAASLQTFVLDDTLPEEKRE +LLVEWLVGNTAADDLIRAGVPDDWTVGDRTGAGGYGTRNCIGVVWPPGRDPIVMVFLSTR +ETEGAERDDQLIAAAAEVIAEAf +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. TaxID=1883446 RepID=A0A522G2Y2_9GAMM +--AAQAQLAELEHRHGGRLGVAILDVAGTRRV-GYRADERFLMCSTHKVLTVGAVLARVD +AGREQLDRRMIFGRDALLAWAPVTSKHVGAPLSVGELCAAAITVSDNTADNLLLTSLGGP +HAVTAFARKLGDRLTRLDRFEPELNQGAPGDLRDTTTPNAMLGSLHALLLGDALSAASRA +QLATWLRAASTGRGRLRAGVPHDWIAGDKTGTGPHGESGDVAILWPPHRKPLLVAAYYVN +PDLGADSPDPVFAAVGRIAA--- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI001011B42B +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAVRDDGLVADAARVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. 275MFSha3.1 TaxID=1502746 RepID=UPI0008A7C60D +---AEPDWAAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKALAVAAVLARVD +AGRETVDRVVSYGAGDLLSYAPVTRKALEAGMSVADLCAATLIWSDNTAANLLLADLGGP +EALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMLATLGRVLLGTVLSAASRA +RLEAWMVACETGRKRLRAGLPPDWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTE +STASPDTCAAAYAEIGRLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Tamaricihabitans halophyticus TaxID=1262583 RepID=UPI001053AEB0 +------ELSTLESENGRRIGVYARHTGTGETV-AHRADERFLMCSTAKLLAASAILKQHE +QQPDLLDKVIHYDREVLMPYSEITEQHVDKGMTVAELAAASITHSDNAAMNLLLDELGGP +SVVTDFVRDLGDEVTRLDRIEPHLNVSAPGDERDTTTPERIGSDLRALALGDALAEQGRA +RLVRWLRGNTTGDKSIKAGLPRDWQVGDKTGSGNNGEVNDVAVAWPPDGDPLIIAVYTAP +DGAERDNGYETVAAAAKIAAE-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000D6780E0 +----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPGGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces aureus TaxID=193461 RepID=UPI00099E9043 +--DLVARLRELEERHSARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTFAVAAVLRDLD +HDGSFLARRIRYTDADVKRWSPRTEENLANGMTVAELCDATLRFSDNTAANLLLRELGGP +TSVTRFARSIGDRTTRLDRWEPELNSAEPWRETDTSTPRAVGRSYGRLVLGDALPRRDRE +RLTGWMLANTTSGERFRKGLPADWILADKTGGGRYGGNNDAGITWPPDGGPIVLTVLTTR +FVEDAAPVDALVADAAALVAA-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI0010202A3B +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAVVLRDLD +RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas desiccabilis TaxID=429134 RepID=A0A4Q2IWF2_9SPHN +-----DPLAAIASEAGGRLGVSVLDTGTGRRL-WLDPLARYPLCSTFKVPLAAAILARAD +RGELDVQRPIRFTQGDLLEYAPVVRENLSRGMTLAELCAAAIEWSDNAAANLLLPQLGGP +SGLTRFLRSAGDSITRLDRVEPELNEYKPGELRDTTTPMAMTTLLAALLTGDVLQPTSRK +QLADWMIGSRTGDKRLRAGLPKGWRVGDKTGTSGNGQANDIAIAWPPNRKPILIACYLDA +PGIAPEKADRAIASVGALVGQL- +>[subseq from] Beta-lactamase n=1 Tax=Kribbella sp. ALI-6-A TaxID=1933817 RepID=A0A1V2PE25_9ACTN +----AADFQRLESRFAARLGVYAVDTGTGREI-AHNADARFPYASTFKALAAGAVLRKNK +--LAGMNKVVKYSTSDLEPNSPVAEKHVATGMTLLALSDAAVRYSDNTAANLLFAELGGP +KGLEAILRELGDNVTSMVRDEPEMSDWDPKNPRDTSTPRAFAKNLRAMVLGDALAKPERD +QLITWLKTNTTGAELIRAGVPKSWVVGDKTGTAGYGGRNDIAVIWPPGRSPIVVAVFSNR +RAPEAEPDNRLVAEAAKVVAS-- +>[subseq from] class A beta-lactamase n=1 Tax=Labrenzia alexandrii TaxID=388408 RepID=UPI0006E1C826 +------VAKAIESRLNTRIGVAVFDPASGLNW-NYNGDDRFPMNSTMKAFACAALLERVD +KKQSSLDQRTIITGDMIVSYSPVTENYINTAMTLADHCEATVTISDNTSANIILDELGGP +IGVTTYMRSIGDDVTRLDRNEPSLNEGTPGDPRDTTTPVAAAQSLYKVLFSDELSASSRK +QLMQWLEANKVGDATLRAGLPHDWRIGDKTGAGAYGSRGNIAIIWPPNHTPVALAVYVTE +NEAEFQARNKAIAEIGAAFK--- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. UNCCL125 TaxID=1502759 RepID=A0A1I7L6C5_9RHIZ +-----PDWGTLERRLDGRLGIAAA-TADRVLA-AYRADARFPMCSTFKVLAVAAVLARVD +TGRETLDRIVAYGSGDLLSYAPVTRKALEAGMTVSDLCAAAIVWSDNSAANLLLASLGGP +EALTAWLRGTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRASLGRILLGTVLSPASRG +RLEAWMIACETGRKRLRAGLPPDWIVGDKTGSGDNGSVNDIAILRPPGRAPVVVAVYVTG +STASPETYEAAYAEIGRLIA--- +>[subseq from] Beta-lactamase n=2 Tax=Mycobacterium haemophilum TaxID=29311 RepID=A0A0I9YWN3_9MYCO +---LSQSFAALERKYDARLGVYALSTTTATTI-AYRADERFAFCSTFKAPLAAAVLQGHP +--VAYLDTVISYRQDAIHAASPITEQHVETGMTIGQLCDAATRYSDNTAANLLLNDIGGP +AGFTTYLRSLGDTVSRLDQAEPEMNRNPPGDERDTTTPRAVGGVLQKLILGDALTSDKRA +MLTDWMVRNTTGNKRIRAGFPADWKIADRTGSGDYGRANAIAVVWSPAGAPSVVAIMSDR +NGYEAQPSDALIADAAAGVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=A0A125PVM5_XANCT +-qTLAQRLAGIERRTGGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFVLTAAVLQRVD +RGELSLQQRLPVRAADMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP +PGLTRFLRTLGDAQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDVLRPASRQ +CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG +AKVDEAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus iheyensis TaxID=182710 RepID=UPI000984127E +----SEAFKKLEDEFDVKLGVYAIDTGSNKEI-NYQENDRFAYASTFKPLAVGAILQTKS +--DPELQEVIRYTEEDLVTYSPITEKHVDEGMTLLEISDAAIRYSDNTAANLLLEAIGGP +DELETKLRDIGDETIEVDRYETELNEATPGDIRDTSTPKAMANSLQQYVLEDVLDADRRE +ILTNMLINNTTGDALIRAGVPEGWTVGDKTGAGGYGTRNDIGIIWPEDNEPIVIAIMSSR +DVEDADYDDKLIEKATKVVVKE- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCSS17_016 TaxID=2175644 RepID=A0A2W1TKI9_9MICO +--ATARAFAALERRYDARLGVAAIDTGSGRKI-AHRAGERFAFASTIKVFIAAAVLDASS +--DADLATVVHYDRGDLLEYAPVTTEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP +EAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTTTPERFAADLRTMLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR +ADPGAEPSDELVAAATRTAV--- +>[subseq from] Beta-lactamase n=1 Tax=Lentibacillus amyloliquefaciens TaxID=1472767 RepID=A0A0U3WIM7_9BACI +-----EKFVQLENEFDAQISVYAMDTGTNQTI-EYRPNERFAYSSTFKPLAAAILLKQNN +--IENLEKVVTYTNDDLVTYSPVTEKHVDAGLTLLEISEAAIRKSDNTAGNLLLEAIGGP +DKFEHALRDIGDDVTQPERYETELNEFTPGNKRDTSTPRAMATNLKKVALGDFLPDDKRE +LLIDWMTGNESGDPLIRAGAPEKWTVVDKSGAGTYGTRNDIAVVWPPNKEPIVIAIMSRH +DTENAEYDDALIAKAAEITLNAf +>[subseq from] Beta-lactamase class A n=2 Tax=Labrenzia alexandrii TaxID=388408 RepID=A0A5E8H1I6_LABAD +------VAKAIESRLNTRIGVAVFDPASGLNW-NYNGDDRFPMNSTMKAFACTALLERVD +KKQTILDQRTIITGDMIVSYSPVTENHINTAMTLADHCEATITISDNTSANIILEELGGP +NGVTTYMRSIGDDVTRLDRNEPSLNEGTPGDPRDTTTPVAAAQSLYKVLFSDELSASSRK +QLMQWLEANKVGDATLRAGLPHDWRIADKTGAGAYGSRGNIAIIWPPNHTPVALAVYVTE +NEAEFQARNKAIAEIGAAFK--- +>[subseq from] class A beta-lactamase n=1 Tax=Actinotalea ferrariae TaxID=1386098 RepID=UPI0012DCA0CE +------ALADLEASFDARLGVVAVDTGSGRRV-EHRADERFAYASTIKALLAAAVLDSTT +--DEELDEVIRFTSSDLVTYSPVTEDRVGEGMTRRELADAAVRFSDNTAANLLLEDLGGP +EALARALRAVGDDVTLPVRTEPALNEAVPGDDRDTSTPRALAASLRAFAVDDALSATDRQ +VLNGWLQGNTTGDELIRAGVPAGWLVGDKTGSGGYGTRNDIAVITPPGRPPIVLAVLSDK +GEVDAESDPALIAAATRVALE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NEAU-C151 TaxID=2580423 RepID=A0A5R9F963_9ACTN +----TGELKELERKFDARLGVYAIDTGTGREV-AYRDGERFGYHSTFKALAAGAVLRKYR +--LTGMNEVIKYSKDDLVHNSPVTEKHVETGMTLRELCDAAVRYSDNTAANLLFDALGGP +KGLEAQLRKLGDDVTMMERVEPGLSDWGPGEKRDSTTPRALAKDLRAYVLGEILRKPERA +ELTKWLKTNKTGDELIRAGVPEGWVVGDKTGAGGYGGRNDIAVVWRPGAAPIVMAIMSNR +DKAEDTYDNKLIAEAATVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. TaxID=1831 RepID=A0A520FI32_RHOSO +--SLDAKIDELEARYSTRIGVTAVDPTTGVTY-SHRGDERFAMCSTFKAYASAAVLRATE +DGSVSLDKAVVIEPGDLVENSPVTAAAAGTRMSLGQIAEAALTQSDNTAGNYLLREIGGP +AAITALARDLGDESTRLDRWETELNTAFRGDPRDTTTPNGLAQGVRALLLGDALDTASRE +QLLDWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWTPDGNPIVLTLLTDS +LTEDAQGNNQAIADTTAAVIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=UPI00082F6043 +-----ARMRELEREYDARLGVFALDTGTGRTV-AHRADELFPVCSVSKTLAVGAVLRDLD +RDGEYLARRVRYTEDDVKTHIPVTGANIANGLTVEELCAAAVSYSDNGAMNLLMRGLGGP +AAVTRFCRSLGDPTTRLDRWEPDLNSAEPGRVTDTTSPRAIGQTYARLAVGRALDAGDRK +RLAGWLVANTTGDARIRAGVPAGWTVGDKTGTGRYGTTNDVGIAWPQDRAPIALAFLSTR +QEQDAKAVDGLIAEATALAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rishiriensis TaxID=68264 RepID=UPI000D5A1B30 +---VTARLRDLESRHGARLGVFAYNVRTRRRV-RHRADELFPVCSLFKTLAVAAVLRDLD +--AAAQDRRIHYTADDLVENSEITKDHVADGMTIAELSAAAIQHSDNTAGNLLLRELGGP +AAITRFARSVGDRVTRLDRWEPELNSAEPGRITDTTSPYAIARTYARLVLGDALSAPDRR +RLTDWMLGTVTSANRFRAGLPPTWTVADKTGGGWYGADNDAGIAWTPDGAPVVLAVQLTE +PDREAPYDHALIVETAGVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Delftia acidovorans TaxID=80866 RepID=UPI000BC3095E +-qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ +QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP +QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA +LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE +CPADAPQRDAALAAAGKAAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces bikiniensis TaxID=1896 RepID=UPI0004BFA31D +---HRREFRALESAFDARLGVYAIDTGTGREI-AYRDGERFPYASTFKALAAGAVLREEE +--LSGMERVVRYTEDELVDPSPVTEKHVGTGMTLDALADAAVRHSDNTAGNLLFEELGGP +KGLQAVLRSIGDDVTRMDRIEPELGDWRPGEVRDTSSPRALARDLRAFVLGDVLRAPERE +RLTTWLKTNLTGDETIRAGVPDTWVVGDKTGTATYGGRNDMAVVWPPDGAPIVMAILSTR +SDREAEPDNRLIARAASVVA--- +>[subseq from] Beta-lactamase n=1 Tax=Delftia sp. JD2 TaxID=469553 RepID=A0A1C7LIZ1_9BURK +-qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ +QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP +QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA +LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE +CPADAPQRDAALAAAGKAAA--- +>[subseq from] Beta-lactamase n=6 Tax=Delftia TaxID=80865 RepID=A0A1I0X5A2_9BURK +-qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ +QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP +QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA +LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE +CPADAPQRDAALAAAGKAAA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium neotropicale TaxID=1497615 RepID=A0A176Z6A1_9BRAD +------ELASYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLSATIPYSQADLLEYAPVARQNLAAGMSVADMCKAIVELSDNTCANLLLARVGGP +AALTAFWRTIGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVLGESLSPASRG +QLTDWMVNCKTGANRLRDGLPGTWKIGDKTGNNGKDASGDLALVWPSPDKPLVIAAYTQG +GTPSPAQIEAVFARTGRIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Ruegeria sp. A3M17 TaxID=2267229 RepID=A0A366X5I3_9RHOB +-qTLTETVQRWERRLDARIGLLLYDPSNEWEV-SYRADELFPMSSTFKPLLCGAVLAEVD +AGTESLSDHVTYQSTDLVDYSPVTSKHVETGMTVGALCEATMTISDNAAANLLLRHLDGP +AGLTEFLRTNGDDITRLDRWETALNEATPGDPRDTTTPRAILATLDRLLFGRALSPASST +QLRQWMIDDQVADGLIRAQVPDGWTIGDKTGAGGHGSRAIVAFLQTPGPRTYLAAIYLTE +SDAPLPERNAVLSDIGRAMI--- +>[subseq from] Beta-lactamase n=1 Tax=Hyphomicrobium sulfonivorans TaxID=121290 RepID=A0A109B9J3_HYPSL +--DVEARLAEIAQNAKGRLGVTIIDTQTGERY-GHHWNERFPMCSTFKLLAGAFVLDRGD +HDEDNIDRKIKFTADDIIDHSPITKDRVGGDMTLRELAQAAVTHSDNTAANLVLDNVGGP +QGLTAYLRSLGDAATRLDRKEPDLNEVPKGDPRDGTVPRVISSTVHRILLGNVLSNTSRD +QLTEWLKASTTGKERIQAGLKDGWTAAGKTGTCANGSTNELAIIYPPNRDPIIAAVFLTD +SDASLDDRNKVLAEVGRTISDMy +>[subseq from] Beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=A0A2K9MRW1_CLOBO +--QYNSAFSQLESDYDVKLGIYALDTEMNKEV-AYHADDRFAYCSTFKALAAGAVLKQDS +--LDELKQVVKYKKEDVLSYAPIAKDNVDKGMTIEEICNAAVRFSDNTAANLLFNHIGGP +SGFKSALNQIGDNVTQPARIEPELNEAMPGDIRDTSTPRQLATDLQAYTTGNILTDDKKR +ILIDWMTGNATGNTLIRAGAPDNWVVADKSGTGPYGTRNDIAIVMPPNKKPIIIAILSTH +HTKEAKYDDKLIAQVSKIVFDSf +>[subseq from] class A beta-lactamase n=1 Tax=Delftia sp. GW456-R20 TaxID=1827145 RepID=UPI0007AE3B98 +-qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ +QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP +QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA +LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE +CPADAPQRDAALAAAGKAAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Delftia sp. CH05 TaxID=2692194 RepID=UPI00135E9C20 +-qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ +QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP +QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA +LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE +CPADAPQRDAALAAAGKAAA--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00099D274F +-------LRALEREYGARLGVYALDTATGRTV-VHRADELFPMCSVFKTLAAAAVLRDLD +HDGAHLAKRIHYTPQDVTDGGSITEKNIANGLTVAELCSAAIAQSDNAAGNLLLRELGGP +TAITRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLALGDALDSGDRE +LLDRWLLSNTTSGDRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPMVLAVLSTM +PEATAPRDNTLIARTAKLLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Labrenzia alexandrii TaxID=388408 RepID=A0A0M6ZPT8_9RHOB +------VAKAIESRLNTRIGVAVFDPASGLNW-NYNGDDRFPMNSTMKAFACAALLERVD +KKQSSLDQRTIITGDMIVSYSPVTENYINTAMTLADHCEATVTISDNTSANIILDELGGP +IGVTTYMRSIGDDVTRLDRNEPSLNEGTPGDPRDTTTPVAAAQSLYKVLFSDELSASSRK +QLMQWLEANKVGDATLRAGLPHDWRIGDKTGAGAYGSRGNIAIIWPPNHTPVALAVYVTE +NEAEFQARNKAIAEIGAAFK--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis antarctica TaxID=1854586 RepID=A0A263D103_9PSEU +----RERLAELERRFDARLGLYALDTGSGSAI-EYRADERFAFCSTFKGLAVAAVLSRNP +--PSHVDTVVTYTEDDLLKSAVVTEEHVATGMTIGGLCDAAIRYSDGTAANLLVRDLGGP +AELTEYARGLGDTVTRMDRIEPAITEAIPGDPRDTTSPRAFAADYRAMVLGEALPAGSRD +FLRDLLERNTTGAKRIRAGVPDDWVVADKTGTGDYGTVNDIAIVWPPGSAPLVIAAMSSK +ATRDAGYEEALLAEAAAHVVA-- +>[subseq from] Beta-lactamase n=2 Tax=Variovorax sp. BK119 TaxID=2512129 RepID=A0A4Q7SPK9_9BURK +---ALSALAAIERRSGGRMGLHAIDTGSGRTL-GHRAGERFAMASTFKLLLAAAVLHRED +RSPGLLDQRLPVRQADLITHSPVTSRHLAAGITAREACEATVQVSDNAAANLLLPLVDGP +AGLTAFVRECGDVLTRLDRNEPALNTNLPGDPRDTTTPAAMAGTTQRLLTGPVLSAASRD +QLRGWLEAASTGMARLRAGLPKDWRTGDKTGTGANGAANDVAITWPPGRAPIVLAVYLDG +STQPAPVLDATHAQAAAVVAARf +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=A0A1A3JVD1_MYCGO +--DLTSRFTEIERRYQGRLGVYVPASGATPAI-AYRADERFALCSTFKAPLVAAVLHQYP +--LTYLDQRVTFSKADISSPSPIAEQHIDTGMTVGEMCDAAIRYSDNTAANLLLNRIGGP +AGFTAYLRSLGDSTSRLDHGEPELNRDPPGDERDTTTPHAIAVAIQQLVLGDALPQDKRA +MLTDWMARNTTGGKRIRAAFPADWKVSDKTGSGDYGRANDVAVVWSPAGTPHVIAIYTDI +AGYDAQPNEAFVADAARVVAS-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces specialis TaxID=498367 RepID=UPI00099E5E3F +----ARAFRELEGEFDARLGVYALDTGTGREV-AYQEDERFAFASTFKALLAGAVLQEYG +--LDGLDEVVTYSSGDLIANSPVTENFTETGMSLRELCAATLWYSDNTAANLLLDALGGP +DALEAVLEEHGDDVTEMDRYEPELSDGVPGDIRDTSTPRAMAGNLRAFLLGDALERDERE +LLTRWMTTNTTGETLIPAGLPDGWTVADKSGTAGYGGRNDIAVIWPDDGNPIVMAVMSSR +DEEGAERDDELIARAATVALE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0K0N4T7_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGK----------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM1417 TaxID=754500 RepID=UPI000485BB61 +------ELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEDQLAAMIPYGKADLLEYAPVAKQNVAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLRRLVTGEALSTTSRA +QLTEWLVGCKTGANRLRAGLPASWKIGDKTGNNGKDASGDIAVAWPKDTAPILIAAYTQG +GTPSAAQIETVFARIGHMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. C1 TaxID=1479019 RepID=UPI0008D9C6B4 +----EPDWTAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKVLAVAAVLARVD +AGRETLGRIVTYGPGDLLSYAPVTRKALEAGMSVADLCAATLVWSDNAAANLLLADLGGP +AALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRILLGTTLSPASRD +RLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGDNGTVNDVAILRPPGRAPILVAVYVTG +STASPDTCAAAYAEIARLIA--- +>[subseq from] UPI000FE182C0 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI000FE182C0 +---YNSAFSQLESDYGAKLGVYAFDTETNKEV-AYRADDRFAYCSTFKALAAGAVLKQDS +--LEQLKQLVKYKKEDVLSYAPIAKDNVDKGMTIEEICSAAIRFSDNTAANLLLNHIGGP +KGFKSALNQLGDSVTQPVHIEPELNEGIPGDIGDTSTPRQLATDLQAYTTGNILTEDKKK +ILIDWMAGNTTGNTLIRAGAPKSWIVADKSGTGPYGRRNDIAIVMPPNKKPIIIAILSTH +DTKEAKYDDKLIAKASKIIFDSf +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_042 TaxID=2175626 RepID=A0A2W1NUV3_9MICO +--ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTVKVFIAAAVLDASS +--DADLATVVHYDRGDLLEYAPVTSGHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTRVDRAEPDLNQAVPGDRRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRGPVVLVVMTSR +ADPGAEPSDALVAAATRTAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium haemophilum TaxID=29311 RepID=UPI0012E007ED +---LSQSFAALERKYDARLGVYALSTTTATTI-AYRADERFAFCSTFKAPLAAAVLQGHP +--VAYLDTVISYRQDAIHAASPITEQHVETGMTIGQLCDAATRYSDNTAANLLLNDIGGP +AGFTTYLRSLGDTVSRLDQAEPEMNRNPPGDERDTTTPRAVGGVLQKLILGDALTSDKRA +MLTDWMVRNTTGNKRIRAGFPADWKIADRTGSGDYGRANAIAVVWSPAGAPSVVAIMSDR +NGYEAQPSDALIADAAAGVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDD50FA +----EAELAALESRHPGRICVSILDMASGKRI-EHRARERILMCSTFKALAAALVLARID +RGQEKLDRRIRYTKSDLVDGSPATKAHVRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP +KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS +QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI +PAIAAGERNGIVAEIGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. Root483D2 TaxID=1736545 RepID=A0A0Q7PL10_9RHIZ +----QEAALLIEERLDARVGYAIYNSGNGESW-LFNADERFPMVSTFKALACAALLAKAD +TGEKSLDNTIEINDSDLVTYAPVTKDWVGREVSLGDLCDATTRTSDNPAANKILENIGGP +EGFTAFMRTIGDNITRLDRWETELNEGTPGDERDTTTPRAIALSLQNLLLGDSLSRNSRE +QLAAWLKGNEVGDPLLRAGIPKNWQIADRTGAGGHGTRGIIAVIWPPEKAPLVAAIYITE +TDATMDERNTAISQMGQALAK-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium japonicum TaxID=375 RepID=A0A0A3XW37_BRAJP +------ELESYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARAD +RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPEAMAGNLKRLVVGEALSPASRT +QLTEWMVGCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKNKVPILIAAYTQG +GTPNAAQIEAAFARVGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD133 TaxID=1053233 RepID=R8E0T4_BACCE +-----------------------MDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI0013DD2CED +--DAERRLAGLERASGARLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPDLNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00115F0F9A +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALRPDG------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Delftia acidovorans TaxID=80866 RepID=A0A087EKY6_DELAC +-qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ +QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP +QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSLLDGHGRA +LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE +CPADAPQRDAALAAAGKAAA--- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. 150FB TaxID=1576605 RepID=A0A0C2B7T8_9ACTN +--RAEKQLAALEARFGGRLGVYALDTGTGREV-RHRADERFLLCSTHKALAVAAILRARR +LRPGLLDTVIHYDSSELVSNSPVTGEHLDEGMTVAALCEAAITVSDNTAANLLVRVLGGP +RAVTRFVSTLGDPVTRVDRTEPELNEA--TGDLDTTTPGHIGADLRALTLGQALDPAGRD +LLVGWLTANTTGGEEIRAGVPAGWRVADKTGSGNNGESNDIAVVYPPGRAPLILAVYTAP +TDPDSTAGSPTIAQAARIVAE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=D2CGR8_STEMA +---TANDFAALEMACAGRLGVTLLDTASGRRL-GHRQDERFPMCSTFKSMLAATALSQAE +RAPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATVITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPEMNSFAEGDPRDTTTPAAMAATLQRVVLGDVLQPASRQ +QLSDWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA +SAISNEQRAGVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. LD6 TaxID=2547393 RepID=UPI0010607175 +-----DDFTALEHDAGGRLGVFAIDTATGKQV-GHRADERFPVCSTFKLILVGAVLTRGV +TEPALMQQRLRYSSNDVVTYSPVTGPHAGDGMTVAELCAATLEYSDNTAANVLVKMLGGP +AAITSFARSIGNATFRLDRLETELDTSIPGDPRDTATPASMAHSTQSLALGDALPAPQRQ +QLKDWLIGCKTGQHRVRAGVPATWTAGDKTGTGEYGTTNDLAVLWPDASGPIVLGVYYTQ +STQNAQPRDDVIAAAARIAVR-- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_026 TaxID=2175621 RepID=A0A2W1RB77_9MICO +---TARVFAALEQRYDARLGVVAVDTGNGRTI-AHRAGERFAFASTIKVFIAAAVLDASS +--DADLAAVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP +DAVERWLRGVGDRTTHVDRVEPDLNEATPGDRRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRAADKTGTASYGVRNDIAIVTPPGRAPIVLVVMTSR +ADPDAEPSDALVAAATRAAV--- +>[subseq from] Beta-lactamase n=1 Tax=Inquilinus limosus TaxID=171674 RepID=A0A211ZLP4_9PROT +---AAARLAELERAHGGRLGVAALNLATGARI-GHRADERFLLCSTFKALAAAFVLARVD +RKQERLDRRIVIARKDLVGKSVLEPRVGGAGVTVAELCDAAVTDSDNTAGNLLLASFGGP +AGLTGFLRSLGDEVSRLDRTEPTLNAAAPGDPRDTTTPAAVLETLRKLVFGDALSAASRH +RLAAWLITNKTGDTRLRAGFPAGWLVGDKTGTGGEGSTNDIAVAWPTDRGPVLVAAYCEL +PSLSFAQRNPVVAEIGRIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Salipaludibacillus agaradhaerens TaxID=76935 RepID=UPI000998D25E +--TVEDTFSQLEGEYDARLGVYALDTGTGKTV-TYRSDERFIYASTHKPLSVGVLLQQKS +--IADLDELITYSSEDLVNYNPITENHIDSGLTLKELSDASIRYSDNTAANLIFHEIGGP +EGFKEGLRAIGDNVTEPERIEPELNDVEPGDIQDTSTPEALAKSLQQFTLGDALADDKQA +LLIDWLKRNTTGDALIRAGVPEGWEVGDKTGSGSYGTRNDIGIIWPPDRDPIILSVLTSK +EERDAEHDDALIARATEEVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces clavuligerus TaxID=1901 RepID=UPI000D0AB075 +-----ADLAALEREHGARLGVYALETGTGAEV-AHRADERFAFCSTFKALAAAAVLHHHP +--IRHLERRVTWTRADVDSISPVTEDHIATGLTVGQLCDAAIRHSDGTAGNLLMRDLGGP +SRLTAYLRGLGDSVSRMDQYEPELNHDPPHDPRDTTTPRAIASDYRKLVLGDALTPDRRA +LLTDWLVRNTTGGRRIRAGVPSGWRVADKTGTGNYGRANDIAVLWPPRSSPLVVAVMSDR +PGFRTPPSERLIAEAAERIV--- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCSS17_011 TaxID=2175643 RepID=A0A2W0DWD6_9MICO +---TARIFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTVKVFIAAAVLDASS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP +DAVERWLRAIGDRTTSVDRVEPDLNEATPGDRRDTTTPERFAADLGTVLLGDALDAADRR +VLRAAMLRNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSR +ADPGAEPSDALVAATARAAV--- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. HMWF018 TaxID=2056855 RepID=A0A2R7P7Y3_9BURK +--AWNDALASIERAAQGRLGVAMLDTGSGLAL-GWQQDERFALASTFKLVLAGWMLALVD +QGKERLDARVHYPATDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDEVTRLDRTEPALNEAAVGDPRDTTTPLAMQQTMQKLVLGNALSPISRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTAGSGTANDIGVLWPQDGAPVLVTCYLTR +SKASPEPRDAAIAQVARAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID2999 TaxID=2690258 RepID=UPI001368737B +---LRSELAALEKRYGARLGVYAHNTRTGATV-AYRADEPFAMCSTFKAIAAAAVLRDHG +-GRAALGEVIHYPPADILSNSEQTKAHQETGMALGDVCAAAIQYSDNTAGNLMLRRIGGP +AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPRALGRTFELLTLGRALSDGDRE +QLVGWLRGNTTSGRRFGAGLPSGWVLADKTGTGSYATANDLGVAWTGKGTPLLLSVLSTR +PAPDAAVDEALIEETARLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Delftia acidovorans TaxID=80866 RepID=UPI00034E6FFF +-qAFRTELARIEKSVGGRLGVAVLEVESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ +QGDERLSRRVRYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP +QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA +LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE +CPADAPQRDAALAAAGKAAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. CYP1-5 TaxID=2604572 RepID=A0A5D3FMW9_9ACTN +--AVAAKLRAVEKARGVRVGAYAVDTGTGRFV-SYRGGERFPFASSFKAMACGAVLRKAD +SDRTLMDRVIRYKKSDLADFSPVTKKHVGTGMTVADLCHATITQSDNTAGNLVLKLIGGP +PGLTAFFRSLGDTSSRSDRREPGLNHWRPGEPRDTATPAAWAGDLRALTVGDALAQPDRA +RLIGWLKATVTGDKRIRAGLPKSWTVGDKTGTAGYGHAVDIAITWPPNRAPLVMAVMTTR +PGADDAADEKAVAETARILAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ST1020 TaxID=1848901 RepID=UPI000DD841ED +-------FAGLEEEYAARLGVFAHDTATGRTL-THRADERFPMCSVFKAPAAAAVLRDGV +----DPAKRIHYTQQELTDYAPVTEKHLDTGMTVEELCAAAVSHSDNAAANFLLRELGGP +TAITRFARSLGDPVTRLDRWEPDLNSAEPWRTTDTTTPHAIARTYAKFLLGDVLRPADRT +RLTSWMVANSTNVTRFRAGLPADWILADKTGGASYGVANDVGVVWPPGRAPLVIAVLTTT +YAAEGPSKNELVAKAAARVA--- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus thuringiensis YBT-1518 TaxID=529122 RepID=V5M6J9_BACTU +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTS--LAVGALLRKNS +--LEALDQRITYTHEELSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIADATKVVLN-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000D0E1101 +----ASDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPSLLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPALRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Root1304 TaxID=1736450 RepID=A0A0T1SBM5_9ACTN +-----ARLRELEQRHSARLGVYAHDVRTGRTI-AYRAGERFPMCSVFKTLAVAAVLRDLD +HDGTFLARRIRYTAAEVRRWSPVTGENLACGMTVSELCDATLRFSDNTAANLLLRELGGP +TAVTRFARSVGDPTTRLDRWEPELNSAEPWRETDTTTPRAIGRTYGRLLLGGALAPRDRE +RLTGWMLGNTTSVERFRKGLPADWALADKTGGGRYGSNNDAGVTWPPDGGPIVLAVLTTR +DAEDAAPVDALVAETASVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Leminorella richardii TaxID=158841 RepID=A4FRA8_9GAMM +-dALQQKLADLEKSTGGRLGVALINTADNSQI-VYRGDERFAMCSTSKVMAAAAVLKQSE +TDSRVLSKKRCDYKSRSDQLEPNCQEALGAGMTLAEMSAATLQYSDNTAMNKILTHLGGP +EKVTAFARSIGDTTYRLDRTEPALNSALPGDPRDTTTPLAMAKSLRSLTLDNALGETQRA +QLVEWMKGNTTGDASIRAGLPKNWIVGDKTGSGDYGTTNDIAVIWPENRAPLILVTYFTQ +PQQNAKARRDVLASAAKIVTE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. LLH-Irr-34 TaxID=1564883 RepID=A0A097SRR5_9ACTN +-----VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRI------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. CCBAU 15635 TaxID=1128180 RepID=UPI0004BB5E0E +-----PELETYERDSGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIAYGKPDLLDYAPTAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP +ATLTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALSPASRA +LLTDWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVVWPKPGTPILIAAYTQG +GTPNAAQIEAAFARIGRMVAE-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013D8FF5F +----ASDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPSLLDRRVPVREADLLSHAPVSRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPVAMATTLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWSVGGAPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Enterobacter TaxID=2608935 RepID=A0A3N2EKH4_9ENTR +--ALEAVVKQEEQALNARIGVAAIDMATGKKV-SYRGNERFPLNSTHKALSCAALLSEVD +KGRLALTSSTRFSQSRLVDYSPVTEKFVEPAITWRHLCSAAVSDSDNTAANLVVERVGGP +AAVTRFLRTTGDNVTRLDRDEPELNSAIPGDERDTTTPIAVSQTLQKLALGEALKLPSRR +QLIQWMRDDKVADALLRSVLPAGWSIADKTGAGANGSRSIIAVVWPLTGKPMIVAIYITE +TEASLTQSNEAIARLGKALF--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDDAC8F +----EAELAALESRHPGRICVSILDMASGKRI-EHRARERILMCSTFKALAAALVLARID +RGQEKLDRRIRYTKSDLVDGSPATKAHVRDGMSVAELCAAAVTLSDNTAGNLLLASFGGP +KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTAAAAMLENLRRLLFTDVLSAASRS +QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI +PAIAADERNGIVAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=UPI000D226BDA +--TLAQRLAGIERRTGGRLGVTLLD-GSGAVLgGQRQDERFPMCSTFKFILTAAVLQRVD +RGELSLQQRLPVRASDMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP +PGLTRFLRTLGDAQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDVLRPASRQ +CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG +AKVDEAARDAALKAVAVAV---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A329XMX7_ECOLX +----------------------------------------FPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHHMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. M3 TaxID=295102 RepID=UPI00100F07EB +----EQAFGELEQKFDARVGVYAVDTGSGLTV-THRPDERFAYASTCKALLAGALLKTYT +--LPQLDRRVRYGPGDLVANSPVTEQHVDTGLTVRELCDAAVRHSDNTAANLLFQELGGP +GGLRDALVALGDRTTRCDRIEPDLSEAAPGDVRDTSTPRALATDLRAYALGGALGADARA +VLNDWLERNTTGDALIRASAPAGWVVGDKTGTGGYGTRNDIAVVRPPGSAPIVLAVFSRR +DARDAEPQDALVAGAARVALGAf +>[subseq from] Beta-lactamase n=1 Tax=Actinotalea ferrariae CF5-4 TaxID=948458 RepID=A0A021VVK2_9CELL +------ALADLEASFDARLGVVAVDTGSGRRV-EHRADERFAYASTIKALLAAAVLDSTT +--DEELDEVIRFTSSDLVTYSPVTEDRVGEGMTRRELADAAVRFSDNTAANLLLEDLGGP +EALARALRAVGDDVTLPVRTEPALNEAVPGDDRDTSTPRALAASLRAFAVDDALSATDRQ +VLNGWLQGNTTGDELIRAGVPAGWLVGDKTGSGGYGTRNDIAVITPPGRPPIVLAVLSDK +GEVDAESDPALIAAATRVALE-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=[Pseudomonas] geniculata TaxID=86188 RepID=UPI000D19F265 +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPGSRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA +GAISNEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces cinereoruber TaxID=67260 RepID=A0A5J6IJ10_9ACTN +---HRREFRALEDAFDARLGVYAIDTGTGREV-AYRDGERFPYASTFKALAAGAVLRKES +--LSGMERVVRYTEDELVDPSPVTEKHVGTGMTLDALADAAVRHSDNTAGNLLFEELGGP +KGLQAVLRSIGDDVTRMDRIEPELGDWRPGEVRDTSSPRALARDLRAFVLGDVLRAPERE +RLTTWLKTNLTGDETIRAGVPDTWVVGDKTGTATYGGRNDMAVVWPPDGAPIVMAILSTR +SDREAKPDNRLIARAASVVA--- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Marinobacter TaxID=83889 RepID=A0A653SMQ5_9ALTE +---LLEAVKTVEQRLDARVGIALYDSGTGESW-DYHGDDHFPITSTFKTLACAALLAKVD +NGTVDLDRRVIFSKDDLVTYSPVTETRAEEEMSLRELCEATMATSDNTAANLVLGAIEGP +DGVTAYARDLGDTVTRLDRTETSLNEATPGDLRDTTSPKAMVANLRKLVLGDALSKGSRD +TLVTWLKGNRVSDNLLRAAIPPDWTIGDRSGAGGHGSRSITAVLWPPHRPPLVTAIYITQ +TDASFDERNGAIRDLGGAIVKHf +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Z0DK01_STEMA +---AAADFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSVLAATVLNQAE +RTPALLDRRVPVHEADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces cyaneofuscatus TaxID=66883 RepID=UPI0004CB14E2 +---TDRAFAELERTFDARLGVYAVDTGDGRTI-AHRPDERFAYASTCKALLSGAVLAKKT +--LPQMERLVRYGQEEIISNSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP +RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALAADLRAYTLGSALPAEKRA +VLIDWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVWPSGGAPIALAVLSRR +DIKNAETDDALIAGAAKVALGAf +>[subseq from] Beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=A0A1J1CUK5_CLOBO +---YNSAFSQLESDYDVKLGIYAFDTEMNKEV-AYHADDRFAYCSTFKALAAGAVLKQDS +--LDELKQVVKYKKEDVLSYAPIAKDNVDKGMTIEEICNAAVRFSDNTAANLLFDHIGGP +SGFKSALNQLGDNVTQPARIEPELNEAIPGDIRDTSTPRQLATDLQAYTTGNILTDDKKK +ILIDWMTGNATGNTLIRAGAPDNWVVADKSGTGPYGTRNDIAIVMPPNKKPIIIAILSTH +HTKEAKYDDKLIAQASKIVFDSf +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB79_STEMA +----ATDFAALEKACAGRLGVSLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RARPLLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAEGDPRDTTTPAAIAMTLQRVVLGEVLRPASRQ +QLADWLIDNETGDECLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRAMVLAQVGRIA---- +>[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobium TaxID=374 RepID=A0A2U8P3Y7_9BRAD +-----PELETYERDSGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIAYGKPDLLDYAPTAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP +ATLTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALSPASRA +LLTDWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVVWPKPGTPILIAAYTQG +GTPNAAQIEAAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Lysobacter capsici AZ78 TaxID=1444315 RepID=A0A125MNF3_9GAMM +---WRTRLRDLEKHSGGRLGVAVLDTGNGERM-LWRENERFRMCSTFKYLLAAAILRQVE +LGKVTLSQQVPITAVDMIAHAPFTQPLVGRSASVAQLCEATVTLSDNPAANLLYPLVGGP +QGLTRFLREIGDGVTRTDRTEPTLNSGAPDDPRDTSTPSAQIATMQRLLLGDALKESSRQ +QLIAWLVANKTGDKRLRAGLPAGVRVGDKTGSGDD-ATNDVAIVWPPGRAPLLIVSYLAT +AKLDGAGRDAVLASLARIVSK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-525 TaxID=1463861 RepID=UPI00068B44D5 +--DVTAGLRSLEEQHTARVGVFAHHLGTKKTV-VHRADELFPMCSVFKTLAAAAVLRDLD +RHGEVLYKVVHYTEADLVDGSDQTRAHLADGMTVEQLADVAVRYSDNGAGNLILRELGGP +TAVTRFARSLGDRVTRLDRWETELNSAEPDRITDTTSPRAIAGLYGKLVLGDALRRPDRD +RLTAWLLNNTTSAARFRAGLPATWTIADKTGSGDYGTANDVGIAWTESGDPVVLAVLTTK +PTPDAPYDNQLVANTAELVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces exfoliatus TaxID=1905 RepID=UPI0004C7AA60 +--NLAPRLRELEQLHSARLGVFAHDVRTGRTV-AYRADERFPMCSLFKTVAVAAVLRDLD +HDGAFLARRIHYTKAYVERYSPKTEENLAHGMTVAELCDATLRYSDNAAANLLLRELGGP +TAVTRFARSIGDTTTRLDRWEPELNSGEPWRETDTSSPRAIGRTYGRLVLGDALAPRDRE +RLTAWMLANTTSGERFRKGLPADWLLADKTGGGRYGGNNDAGVTWPPDGGPIVLAVMTTR +FEEDAAPVNALVADAAALVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Devosia limi DSM 17137 TaxID=1121477 RepID=A0A0F5LSE2_9RHIZ +--EFSQRIAELEARGGGRLGVCVIDTATGRSV-AHRGDERFPFCSTYKLLAATFLLKRVE +AGQEQLDRRIRYGVADLVGAAPYTGKYAGGSVSLQRLAEAAMTQSDGTAANLIVETFGGP +AELTRYARTLGDAVTRVDRYEPELAEAVPGDPRDTTSPNAMAENVRKVVMGEALQQAGTA +QMVAWLMANRTGDERLRAGTPDDWIIGDKTGSSRNGATNDIGFMQPPGRSPLIVAAYYAE +SKLNSAGRSAVLADVARVIVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf361 TaxID=1736352 RepID=UPI0006FA2A3B +---AEPDWAAIEHRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKALAVAAVLARVD +AGRETLDRVVSYGAGDLLSYAPVTRKALEAGMSVADLCAATLIWSDNTAANLLLADLGGP +EALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRVLLGTVLSTDSRA +RLEAWMVACETGRKRLRAGLPPDWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTQ +STASPDTCAAAYAEIGRLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Comamonas aquatica DA1877 TaxID=1457173 RepID=A0A014MLP1_9BURK +---WSQAMAQIEQDAQGHLGVAMLDTGSGMAL-GWRQDERFAMCSTFKLPLAAWVLALVD +QGRERLDARVQYSEAELVEYSPVSGPKAGAGLTVGELCSATVSLSDNSAANVLLARHGGP +AALTAWLRSQGDFITRLDRNEPSLNEAAVGDERDTTTPLAMLHTMQRLVLGTALSPSSRA +TLQRWLIETSTGDQRLRAGAP-GWKVGDKTGTSGSGTANDIGVLWPPGGAPVLVTCYLTQ +STARPEQRDAAIAQVARAVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces fulvoviolaceus TaxID=285535 RepID=UPI000694AC09 +-----TGLRKLEARHGARLGVFAHNLATERFV-SHRADELFPMCSVFKTLAAAAVLRDLD +RHGEFLARRIHYTEADLPEGSDKTREHLADGMTVAELADVAITYSDNGAANLLLRELGGP +TAITRFCRSLGDPVTRLDRWETALNSAEPWRITDTTSPRAIGRTYGRLVLGDALGRRDRG +LLTHWLLNNTTSSTRFRAGLPKAWTVADKTGGGSYGTNNNVGIAWTEDGAPIVLAVLTTK +PDQDAARDDELVADTAALIAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium sophorae TaxID=1300294 RepID=UPI000BA43859 +------KIRRIEAKSGGRLGVSCRISGTTAQF-GYRQGELFPMCSTFKALAAAFILHRVD +GGIEQLDRSIKIPHDAVIANSPTTKKHAGGEMTVAQLCEAAVTVSDNGAANLLLESFGGP +AQLTAYLRSIGDKVTRLDRIEPELNESLPGDARDTTSPLAMTGNFERLTIGNSLSEKGRV +QLVDWLVANKTGDERIRAALPKGWTCGDKTGTGAHGSTNDAAVIWPASGNPILMSVYLTG +TKQSLAKRNAVIAAVSHALVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea vagans TaxID=470934 RepID=UPI00066019C1 +-----AVAQQEEQALKARIGIAVIDTDAESVA-SYRGNERFPLNSTHKALLCGALLSAQD +KGKLRLTERTQFDRTALVTYSPVTEKFIAPAMSWGQLCEAAIAYSDNTAANLLARKLGGP +VAVTRFFAELGDKVTRLDRFEPELNSAVPGDMRDTTTPLAVSETLQKLTLGPALTPASRA +QLLQWMRDDKVADALLRSVLPTGWSIADKTGAGEYGSRSIISVVWPENGKPLIIAIYITQ +TEATLAQSNAAIARIGKAIF--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00106F8EA0 +---TANDFAALEMACAGRLGVTLLDTASGRRL-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVRDADLLTHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRVVLGDVLQPASRQ +QLSDWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA +GAISNEQRAGVLAQVGRIA---- +>[subseq from] Beta-lactamase class A n=1 Tax=Devosia limi DSM 17137 TaxID=1121477 RepID=A0A1M5E9U6_9RHIZ +--EFSQRIAELEARGGGRLGVCVIDTATGRSV-AHRGDERFPFCSTYKLLAATFLLKRVE +AGQEQLDRRIRYGVADLVGAAPYTGKYAGGSVSLQRLAEAAMTQSDGTAANLIVETFGGP +AELTRYARTLGDAVTRVDRYEPELAEAVPGDPRDTTSPNAMAENVRKVVMGEALQQAGTA +QMVAWLMANRTGDERLRAGTPDDWIIGDKTGSSRNGATNDIGFMQPPGRSPLIVAAYYAE +SKLNSAGRSAVLADVARVIVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis lexingtonensis TaxID=218822 RepID=UPI000A3955F7 +------DFAPLEREFDARLGVYAIDTGSGREI-AHRADERFGYASTHKAFSAGAVLQRTS +--MEGLAKVLPYTRADVQPNSPVGEKHVGTGLSLRDAIDAALRYSDNTAANLLFRELGGP +AGLAAALRGIGDTTTHVDRIEPGLNDLAPGDVRDTSTPRAMAADLRAFALGTVLPAAQRT +FYTDTMRANRTGDAVIRAGTPAGWTVADKTGTGEYATRNDIAVVWPPGRAPIVLAVMSDR +KTENAEHDDRLLAQAAKLTLDAy +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces avicenniae TaxID=500153 RepID=UPI00069B3FE1 +---TGRAFRALEQEFDARLGVYALDTGTGREV-AHGADDRFAYASTFKALAVGAVLRER- +-GTEGLAEVVTYTEADLVANSPVTENFVDTGMSLRELCAATLWYSDNTAANLLLDALGGP +DGLEAVLRELGDDVTEMDRYEPDLSDAVPGDIRDTSTPRAMADGLRAFLLGDTLERDERR +LLRRWMTTNTTGETLVAAGVPGTWDVADKSGTAGYGGRNDIAVLWPDDGDPIVLAVMSSR +DREGAERDDALIAEAAAVAV--- +>[subseq from] Beta-lactamase n=1 Tax=Kitasatospora sp. CB01950 TaxID=1703930 RepID=A0A1Q5F7D0_9ACTN +----AESFRWLEQHFGARLGVYVLDTGSGREV-AYRADERFAFASTFKALAAGALLRRAS +--DADLDKVVTYRQEDVLTWAPVTSEHVATGMTVRDLLAASLDYSDNTAANLVTDQLGGP +AALQQALRELGDPTTEVSRTEPGLNSATPGDTRDTSTPRALAADLRRYVLDDVLPAARRQ +LLTELMVANTTGGPYIRAGVPAGWKVGDRTGNAAYGTRNDIAVLWPDGGAPVVVAVLSDR +PRQDAASDDALIAQATGAAL--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rubrivivax sp. TaxID=50259 RepID=A0A519HFF2_9BURK +---LREALQHIETTARGRLGVHIIDTANGREH-GWRSDERFLMLSSFKLLASAFVLDRVD +RGVEKLERRIRYRPQDLVPWSPVTERHVGGELSLAQLCEATITTSDNTAANLILASYGGP +AALTAYAWRLGDAVTRLDRTEPELNRAASGEPLDTTTPRAMAHTLNKLLLGDALKPSSRE +LLLNWLLANTTGGKRLRAGVPAGWRIGEKTGTAGD-DANDIGIALPPQRAPIIVTAYLAE +SRTDAATREAALASVGGLL---- +>[subseq from] class A beta-lactamase n=1 Tax=Desertihabitans aurantiacus TaxID=2282477 RepID=UPI000DF75F6D +------AFAELEARWDARLGVFAVDTGSGRVV-EHRADERFAYASTHKALSAAAVLEQTT +--DEELDRLVRFDADDLVEYSPVTEERLAEGMSLRELADAAVRYSDNTAGNLLLDELGGP +AGFDAALEEVGDLVTQVDRLEPELNTAVPGDPRDTSTPRALATSLRAYAVEEALPAGDRE +VLNDWLQRNTTGDALVRAGVPGGWLVGDKTGTAGYGTRNDIAVVHPPGRAPLVLAVLSSR +DEVDAEHDDALVAEATRVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces aureoverticillatus TaxID=66871 RepID=UPI0013DB6236 +----HRQLAALERKFDARLGVYALDTGTGAVI-AHRADERFAFCSAFKALAAAAVLDGNP +--LSHLDDRVRYGKADLMKHAPITSRHVETGMTIRQLCDAAVRFSDGTAGNLLLRDIGGP +DRLTAYARGLGDKVTRMDRFEPAITEATPGDPRDTSSPRAFGSTYREIVLGDALPKSKRA +FLRDLLERNATGAKRIRAGLPRGWTVADKTGTGNHGTLNDIAVVWPPKSAPLLIAIMSSK +AEQDAPYDEALLAEAAAYVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Actinopolyspora mortivallis TaxID=33906 RepID=A0A2T0GT82_9ACTN +-nTVRAEFTRLEQRFGARLGVHALDTGSGEIV-THRADERWAFCSTMKTFTAAAVLRRNT +--VEDLDRRITYTRADLVPYSPVTERHVDSGMTLREVLRAALRVSDNTAQNLLLRELGGP +EGLQRELRELGDTTSHVDRYEPELNEAEPGDVRDTSTPRALAANLREVVLGDALAPEKRK +ILRGAMRNPPLTEELVQAGMPEGWEIEDKSGAGKYATRNDIAVLYPPERDPIVLVVMTSK +SDEDAEYDDALVAEAARTTLD-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013D91D1A +----ATDFATLEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLVATVLSQAE +RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRTSGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Phyllobacterium salinisoli TaxID=1899321 RepID=A0A368K169_9RHIZ +----EGQLAELERRHGGRIGVAVLDLATGQRL-MHRADERFLMCSTFKALTAGFILARVD +QGEEQLDRRIVFSKKDIVVGSPATQERIGGTMSVAELCQATLTLSDNAAANLLLASFGGP +AGLTGFLRSIGDEITRLDRFETDLNHETPGDLRDTTTPAAMLETLRKLLFGNVLSRSSRA +QLAAWMIMNKTGDAKLRAGFPDDWTIADKTGGNGFGNSNDVAIAWSPDRGAVMITAYCEI +PSVSEKVRAAVLAEIGRIAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix deserti TaxID=2593674 RepID=UPI00131C7E29 +--AANDHLVELERKFDARPGVYALATGTGTTI-AHRADERFAFCSTFKTLAAAAVLHRNP +--LSHLDTTIRYTADDLMKSSAITGRHVATGMTIRQLCDAAIRYSDGTAGNLLLRDLGGP +AQLTAYARHLGDTVTRMDRMEPMITEATPGDPRDTTSPRAMGVDHHKIVLGDALPPDKRA +FLRDLLERNATGAQRIRAGVPQGWTVADKTGTGDYGTLNDIAIVWPPGSAPLVISIMSSK +ATKDADYNQALIAEAAGYVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=UPI00071B9A96 +-qTLAQRLAGIERGTGGRLGVTLLD-GSGAVLgGQRQDERFPMCSTFKFVLAAAVLQRVD +RGELSLQQRMPIRAADMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP +PGLTRFLRTFGDAQTRSDRHEPEMNRFAADDPRDTTTPAAMAATLRTLLLGDVLRPVSRQ +RLSEWMIDNRTGDACLRAGLPRGWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG +AKVDDAARDAALKAVAVVV---- +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. JHL-3 TaxID=1276755 RepID=UPI0004B6A277 +--QWSDALAGIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD +QGKERLDARVHYPVAEVVAYSPVSSPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP +AGFTAFVRSLGDGATRLDRTEPTLNEAARGDPRDTTTPLAMLQTMRKLVLGDALTPASRT +WLQRWLVQTSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVLWPPSGAPVLVTCYLTR +STAQPEQRDVAIAQVARAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces novaecaesareae TaxID=68244 RepID=UPI000D11B440 +--DLHRRLADLEQQHSARLGVFARNLTTDRTI-RYRAGELFPICSVFKTVAVAAVLRDLD +HDGEYLARRIRYTQADIDRGAPVTGKNLAGGMTVAELCAAAIDHSDNTAANLLLRDLGGP +TAVTRFCRSIGDRVTRLDRWEPELNSAEPDRTTDTTSPRAIARTYGRLALGHALPPAKRE +RLTAWMRGNTTSTHRFREGLPQDWALADKTGTGEYGTTNDVGIAWTPTGAPVLLAVLTTK +PAPAAPKDEPLVARTAALL---- +>[subseq from] Class A beta-lactamase n=1 Tax=Sinorhizobium saheli TaxID=36856 RepID=A0A178YIJ4_SINSA +-qAAAARLDALERRHPGRICVSILEVASGKRV-EHRADERILMCSTFKALAAALVLARVD +KGEERLDRRIKFSKNDLVAGSAATETHAGGAMTMAELCDAAVTRSDNTAGNLLLASFGGP +AALTAFFRSLGDDVSRLDRIETDLNYDGPDDIRDTTTAAAMLENLRRLLFTDALSPSSRS +RLAAWLITNKTGDSRLRAGVPKNWLVGDKTGTNGHGIANDIAVLWRPDGAPIIVTAYCEI +PSISADERNAVIAEIGRIA---- +>[subseq from] Beta-lactamase L2 n=1 Tax=Xanthomonas translucens pv. phlei TaxID=487906 RepID=A0A0K2ZS65_XANCT +-qTLAQRLAGIERRTRGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFVLTAAVLQRVD +RGELSLQQRLPIRAADMLSHAPVTERDVGGTLSVAELCRATLLFSDNPAANLLFPLVGDP +PGLTRFLRTLGDAQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRQ +QLGAWMIDNRTGDACLRAGLPPGWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG +AKVDDAARDAALKAVAVAV---- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000DAA34EF +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRVGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6B8IJR0_STEMA +----ATDFATLEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase AST-1 n=1 Tax=Nocardia brasiliensis ATCC 700358 TaxID=1133849 RepID=K0EN23_9NOCA +-----AELTALEQQYDAQLGLFAVDTGSGKTL-TNRADQRMPFLSTFKGLAAGALLKAHP +LATGYFDKVVHFTEADLVTYSPVTSTKVAEGMTIAQIADAAITQSDNTAGNLLLRELGGP +QGLTAFLRTLGDQVSRLDRWEPDLNTALPDDERDTTTPAALAADYRALVLGDALGAPERD +QLTKWLKANTTGDKRIRAGVPAGWTTGDKTGTGDYGMANDAAVTWPDGGAPLVIAIQTRK +STTAAEPSNDLVAAATKLVVEK- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis vancoresmycina DSM 44592 TaxID=1292037 RepID=R1GF45_9PSEU +-----PDFAPLERDFDARLGVYAVDTGSGREL-AHRADERFGYASTHKAFSAAAVLQRTG +--LDGLAKTLTYTRADLQPNSPVTEKRVGTGISLRDAMDAALRYSDNTAANLLFRELGGP +AGLAGALRAVGDTTTHVDRIEPGLNDLAPGDVRDTSTPRAMAGSLRAFTLGSALPPDKRA +VLTDMMRANTTGAALIRAGAPAGWAVADKTGTGSYATRNDIAVVWPPGRAPIVLVVMSSR +QGKDAGHDDRLLAQAAKLALDAf +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2J0UDS6_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRS-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDARVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP +PAVTAFLRASGDPVSRSDRLEPELNTFAEGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA +GAISNEQRAAVLAQVGRIA---- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinomadura pelletieri DSM 43383 TaxID=1120940 RepID=A0A495QJ11_9ACTN +--DVTRRLLQLEKARDVRVGAYAIDTGTGQVL-AHRADERFPFASSFKVMACAAVLRKAR +RDPGLMDRVIRYGRNDLSAFSPETEKHVGTGMTVAELCRATITRSDNTAANLLLKQIGGP +QGLTAFFRSLGDTVSRSDRVEPGLNRWRPGELRDTTTPAPWARNLQALTVGDALVPADRA +RLVAWMKATVTGGERIRAGLPGGWTVGDKTGTAGHGNANDIAVVWPPSGAPLILAVLITR +PDADAEADDKAVAATAGILA--- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces sp. M10 TaxID=412968 RepID=UPI0006485E42 +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RDGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCKVSITASDNCAANLTLRELGGP +AAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLTAK +TEQDAVRDDALVADAARVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium ottawaense TaxID=931866 RepID=UPI000BEACA61 +-----PELETYERDSGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIAYGKPDLLDYAPAAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP +ATLTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALSPASRA +LLTDWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVVWPKPGTPILIAAYTQG +GTPNAAQIEAAFARIGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=UPI0009A178E9 +---AVRKLRDLERRHGTRLGVFGWNTVTGRTV-LHRANGRFPLCSTSKTMAIGAVLRDLD +HDGTFLSKVIHYTQQDIDRAAPVTGQNLAHGMTVADLCGAAVSYSDNTAMNLLLAELGGP +AAVTRFCRSLGDTVTRLDRCEPELNSAEPWRVTDTTTPRAIGKTYARLALGNALDKADRT +RLTGWLLANTTGGKRLRAGLPEGWTVGDKTGTGRYGTTNDVGIAWPPGQGPIVMAVLSTR +PEPDAEADDAVIAETAALLA--- +>[subseq from] Beta-lactamase n=2 Tax=Clostridium kluyveri TaxID=1534 RepID=B9E548_CLOK1 +---YNSAFSQLESDYGAKLGVYAFDTETNKEV-AYRADDRFAYCSTFKALAAGAVLKQDS +--LEQLKQLVKYKKEDVLSYAPIAKDNVDKGMTIEEICSAAIRFSDNTAANLLLNHIGGP +KGFKSALNQLGDSVTQPVHIEPELNEGIPGDIGDTSTPRQLATDLQAYTTGNILTEDKKK +ILIDWMAGNTTGNTLIRAGAPKSWIVADKSGTGPYGRRNDIAIVMPPNKKPIIIAILSTH +DTKEAKYDDKLIAKASKIIFDSf +>[subseq from] Beta-lactamase n=1 Tax=Gordonia araii NBRC 100433 TaxID=1073574 RepID=G7H1F6_9ACTN +--STTGRIAALERRHNARIGVFAADLGSERTV-AHRADESFAMCSTFKTYAAARVLQLVE +RGTLSLDTGVFVDAAEIVENSPVTQRHASSTMTVSQLCEAALQQSDNTAGNLLLRAIDGP +QGVTAFARSIGDGRTRLDRWETALNAAVPGDPRDTSTPSALAGGYRALLAGDALSPASRE +RLDDWMRGNQT--SSMRAGLPDGWTSADKTGAGDYGSTNDVGIAYSPGGGRILLAVMIRS +AAPDAEGFRPLIGEVAGLVV--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013DC06D7 +----ATDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAMTLQRVVMGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Lechevalieria atacamensis TaxID=531938 RepID=UPI000DC38FE7 +---ISGKLRDLEQQHGARLGVFATDTGSGRTV-LHRADELFPMCSTFKTIAAAAILRRDH +-NGALLGKVIRYTQEDVTKYGPITGKNLANGMTVSALCEATITYSDNCAANLLLKELGGP +TAITRFSRSIGDPVTRLDRWEPDLNSAEPGRVTDTTSPRAIGQSYARLTLGHALNRADAD +QLTRWLLANTTGGNRIRAGLPTAWRWGDKTGTGKYGTTNDVGIAFPPGRSPIVIAVLSTK +SVQDAPADEPLLAKTAELVAGTf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Root55 TaxID=1736554 RepID=UPI000B000E8A +--RTARAFRGLEREFDARLGVYAVDTGSGLSV-THRSDERFAYASTCKALLAGALLDAHP +--LRRLDRRVRYGPGDLVANSPVTEEHVRSGLSVRALCEAAIRFSDNTAANLLFRELGGP +GGLQDALVALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALAADLRAYVLGDVLAPDARA +LLTDWLRRNTTGDTLIRAGTPDGWVVGDKTGTGGYGTRNDIAVVWPPGSAPITIAVLSRR +AAHGAEPQDALVARAAGVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia acaciae TaxID=551276 RepID=UPI000688E260 +----ADEFGGLEREYGARLGVYAVDTGTGREV-AYHADDRFGHASTFKALAAGAILRRVP +--LDGLNKVVRYARSDLKSNSPITQQHVDTGMTLRAAMDAAVRYSDNTAGNLLFRELGGP +GGLTAALRDLGDTVTRSDRFETELNDVSPGDPRDTSTPRALAGSLRAFTVGTALPEDRRA +LLTDMLRANTTGATLIRAGAPAGWQVGDKSGAGGRATRNDIAVVWPPGRAPLVLAVLSDR +PAPDAPYDDKLIARAAAVAFAAf +>[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000BA1C69B +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAER-------- +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Terriglobus roseus TaxID=392734 RepID=A0A1G7F143_9BACT +-qRLPQQVAALERASGGRIGVYALDTGNGKFA-GNREDQRFPMCSTFKFLLAAAVLKLVD +DGKQSLDQSLPIPNKPLIGHSPLTEPHAGATMSVAALCNAILNQSDNTAANVLLDAIGGP +PAITAFTRSIGDEFTRLDRNEPDLNSSIDRDPRDTTTPVAMAKNLQRILLGNTLKPASRR +QITEWMENSLTGLERLRKDMPEGWRAADKTGSNGEHTTNDIAILWPIHRPPVIVTCYITQ +CPGPETKRGAMIAEVGRFI---- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus opacus PD630 TaxID=543736 RepID=A0A3G9MFC2_RHOOP +---LDATIAALEAQYSTRIGVTAVNPVTGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE +DGSTSLDKTVVIEPGDLVENSPVTAAAVGTPMTLGKIAEAALTQSDNTAGNYLLREIGGP +QAVTDFARVVGDESTRLDRWETELNTAFRDDPRDTTTPNGIAQGFRALLLGDALDTASRD +QLLEWMRASKTSDKRMRAGLPTGWTAADKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS +LTEGAQGNNQAIADTTAAVIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Hydrogenophaga sp. BPS33 TaxID=2651974 RepID=UPI0013200858 +---LQEALRDIERKAKGRLGVHIIDTSTGLEL-GWRSEERFLMLSSFKLLASALVLDRVD +RGVESLQRRIRFSKEDLVSWSPVTERHVGGHMSLAQLCEATLTTSDNTAANLILASYGGP +AALTAYARRLGDSETRLDRTEPALNRAASGEPLDTTTPRAMANTLRTLLLGKALAPESRD +RLTQWLLANTTGGKRLRAGLPVGWQIGEKTGTAGD-DANDIGIAFPVQRAPIIVTAYLAE +SATDAATRENALASVGRLLT--- +>[subseq from] Beta-lactamase n=2 Tax=Saccharopolyspora TaxID=1835 RepID=A0A1H6ELL8_SACHI +------DLAELERRYDARLGLYAVNVRTGRTL-VNRPDERFALCSTFKTYAVAALLRDHG +LSSGYFDKVIRYTEEELVSNSPETEKHVDTGMTVRALCEATMTVSDNTAANLLLRERGGP +QSIAPFARSIGDPTTRLDRWEAELGTAIPGDERDTSTPAGLAAGYRSLVLGDALAAPERD +QLTKWLLANTTGDECIRAGVPPTWRTGEKTGAGDYGTRNDVGVTWTEDGTPIVIAILTTR +PRPDDEYRNELLADTARAVAAH- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TRM68295 TaxID=2569859 RepID=UPI00124B29D1 +-----GELKELERKFDARLGVYAIDTGTGREV-AHRDGERFGYHSTFKALEAGAVLRKYS +--LNGMNKVIKYSSDDLVANSPITEKHVETGMTLSELCDAAVRYSDNTAANLLFDALGGP +KGLESDLRKLGDKVTLMERIEPHLSDWVPGETRDTTTPRALAKDLRAYVLGDVLRKRERA +QLTTWLKTNTTGNEVIRAGVPEGWVVGDKTGSGGYGARNDIAVVWPPDSAPIVMAILTNR +GKAEDVHDNKLIAEAASVVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 351MFTsu5.1 TaxID=1172180 RepID=UPI000376238F +--DVAARLRALEQRYDARLGVFAHRLSTKRSV-RFRADELFPMCSLFKTLAAAAVLRDLD +RHGEVLARRVHYTEDDLVIGSDQTAAHLAEGMTIAELAEVAITYSDNTAGNLLLRELGGP +TAITRFARSLGDRTTRLDRWEPELNTAEPWRRTDTTSPYAIGRTYGRLVLGDALNRRDRE +LLTHWLLSNTTSVNRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTEDGDPVVLSVLSTL +REPDAVRDDALVADAAAVVA--- +>[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus szentirmaii DSM 16338 TaxID=1427518 RepID=W1IQA9_9GAMM +-nQITEKLLILEKNANGRLGAVLINTANHSII-AYRGNERFPLCSTSKFMVVSALLKQSE +TSDHLLNQQVHYQQSDLVEYSPITEKHLKNGMTLGELSSATLQYSDNTAMNLILDALGGP +NEITKFARTIGDKHFRLDRKEPELNTAIPNDERDTSTPQSMADSLYHLALGHALALEQRN +QLVEWIKGNTTGATSIRAGVPKNWVVGDKTGRCDYGSTNDIAVIWPENRPPLVLVTYFTQ +PNKNAVARPDILAETARIMIQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_051 TaxID=2175640 RepID=UPI000DA86239 +--ATARAFAALERRYDARLGIAAVDTGDGRTI-AHRAGERFAFASTIKVFIAAAVLDASS +--DADLAAVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLRGP +DAVERWLRGVGDRTTHVDRVEPDLNEATPGDRRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAIVTPPGRAPIVLVVMTSR +ADPDAEPSDALVAAATRAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Bradyrhizobium TaxID=2631580 RepID=UPI0004B62E4E +-----PELETYERDSGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIAYGKPDLLDYAPAAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP +ATLTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALSPASRA +LLTDWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVVWPKPGTPILIAAYTQG +GTPNAAQIEAAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus sp. GDc328 TaxID=742178 RepID=A0A0M0TCE3_9GAMM +---IIHQLSILEKNANGRLGVVLLDTSDHSII-SYRENERFPLCSTSKLMTVSAILQKNE +TNAHLLNQRVHYQQSDLVEYSPMTEKHLKEGMTLGELSAATLQYSDNTAMNLLLNQLNGS +HEVTRFARTIGDHYFRLDRREPELNTAIPGDDRDTSTPQAMAKSLYNLVLGTALATTQRE +QLTEWIKGNTTGGTSIRAGLPKNWIVGDKTGRCDYGTTNDIAVIWPPDRAPLVLVTYFTQ +PNKEASARPDVLAAATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A0R0BDE5_STEMA +---AATDFAALEKACAGRLGVTLLDTASGRRA-GHRQDERFPMCSTFKSVLAATVLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNRFAEGDPRDTTTPAAMAGSLQRVVLGPVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLRA +GQISYEQQAAVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sinuspersici TaxID=501010 RepID=A0A1V3BYY2_9ACTN +----DSEFERLEEEFDVRLGVYALDTGTDRVV-EFQADERFAYCSTFKALAFGAVLDRTP +--VDGLDRVVTFSEADLVFHSPVTRKHVDSGMTLREIGDAALRHSDNTASNLLLEELGGP +EGLEEALRGIGDDVTRVDRVAPEMAEAVPGDVRDTSTPRAMATSLRAFALGDVLPEDGRG +VLVGMMRANTTGDGLIRAGVPKGWTVGDKTGACGYGTRHDIGVLWPPEGAPVVLAVMSSR +DEAGAEYDDALVAQATELAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NBRC 110468 TaxID=1679753 RepID=UPI000D14B8CA +---VTARLRDLEAAHGARLGVFAHNVRTRRTV-RYRADERFPVCSLFKTLAVAAVLRDLP +--EGTLDRRVYWTAADVVENSPVTQEHVADGLTVAELCAAAVQRSDNTAGNLLLREIGGP +AGLTRFARSVGDRVTRLDRWEPDLNSAEPDRVTDTTSPAAIGRTYGRLVLGDALAARDRR +RLTDWMLGTVTSANRFRAGLPPTWTVADKTGGGWYGANNDAGVAWTPDGAPVVLVVQLTK +PDREAAYDHDLIVETAKVLAE-- +>[subseq from] class A beta-lactamase n=2 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=UPI00071E96B9 +-qTLAQRLAGIERRTRGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFVLTAAVLQRVD +RGELSLQQRLPVRASDMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP +PGLTRFLRTLGDAQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDVLRPASRQ +CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG +AKVDEAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas maliensis TaxID=1321368 RepID=UPI0003A86D5F +--ALRVRWAEIEGRSGGRLGISLLDTATGQRI-EQRQDERFPLCSTFKFLLVAAVLQRVD +RGELRLDRQVPIRAEDMLSYAPATKPHVGGSLSLAELCQAAMIFSDGVAANLLLTQVGDP +AGLTAFIRTLGDTQTRSDRNEPSMNNFALDDPRDTTTPAAMLGSMRAVLVGDALLPASRK +RLTEWMIDNRTGDDCLRAGFPQGWKVGDKTGNNGTDSRNDIGIVWVPGQAPLLLTTYLNK +ATVDADARDAALKAVAQAVAAWw +>[subseq from] Imipenem-hydrolyzing beta-lactamase n=4 Tax=Enterobacter cloacae complex TaxID=354276 RepID=BLAN_ENTCL +-----DEIKNLETDFNGRIGVYALDTGSGKSF-SYRANERFPLCSSFKGFLAAAVLKGSQ +DNRLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILSEHEKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +NEKEAKHEDKVIAEASRIAID-- +>[subseq from] Beta-lactamase n=1 Tax=Pararhodospirillum oryzae TaxID=478448 RepID=A0A512HAI3_9PROT +----AATARAVEARLDARVGVFVVDTGGGTTW-AYRADERFPMASTFKALACGALLARIQ +AGEESADTSVPIEAQDLVSYAPVTKTLVGQRVPVLDLCAITLRTSDNTAANKILEHVEGP +AGLTRFVRALGDETTRLDRWETALNEGIPDDPRDTTSPRAMATTLRALVLGPILSEDGRL +RLVRWLESNAVSGSLLRAGVPADWRIADRSGAGGHGTRGLTAVAWPPGRAPLVIAIYLTK +TEAPMADRDAAIADIGRALV--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE2118D +----EAELAALESRHPGRICVSILDMASGKRI-EHRARERILMCSTFKALAAALVLARID +RGQEKLDRRIRYTKSDLVDGSPATKAHVRDGMSVAELCAAAVTLSDNTAGNLLLASFGGP +KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS +QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVAAYCEI +PAIAAGERNGIVAEIGCIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WM6368 TaxID=1415554 RepID=A0A0M9XXY7_9ACTN +---VVARLRELEREYGARLGVYARDTATGRTV-AHRADELFPMCSVFKTLAVAAVLRDLD +HDGAHLAKRIHYTAQDVTDGGSVTERNIAGGLTVAQLCSAAIAQSDNLAGNLLLRELGGP +TAVTRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLAIGDALDSGDRE +QLNRWLLSNTTSADRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPLILSILSTL +PEPTAPRDNTLIARAAKLLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia kunmingensis TaxID=630975 RepID=A0A543DJ04_9PSEU +---------VLERRFGGRIGVHALDTGNGATV-SHRSGERFLMASTAKLPLAAAVLDRAA +TEPALLDRLVRFGPEALLEYAPVTTQNVATGMTVADLCDAALTVSDNTAANLLLELLGGP +AAVTAFARGLGDATTRFDRSEPELNSTGPDDERDTTTPAAIVASIRAVTLGEGLEPAGRE +RLTAWLVANTTGDATIRAGVPAGWVVGDKTGTGEQGERNDVGIVLPPDRAPLVLAVYTDP +DDPDSTAGNATIAEATAIAVR-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingosinicella microcystinivorans TaxID=335406 RepID=A0A495RY09_SPHMI +--ETLRRLEEIEARSGGRIGFFVRDTGSRRAI-AHRADERFAMASTFKAPLAAAVLAGGE +AGEFRLDRRIPYTAGDLLEYAPVTKRHVSEGMSIEDLCAAIVELSDNTAANLLLPLVGGP +AGFTRWLRGIGDTETRLDRTEPTLNANTPGDPRDTTTPRAMAATLERLLVSDVLPQAARD +RLTGWMVASPTGRDRLRAGLPVDWRVGDKTGTGMNGAVNVIAILWPPKAAPLIAAIYMDG +SKAPLADLNAAHAALGGLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus opacus TaxID=37919 RepID=A0A2S8IQN7_RHOOP +--SLDATIDALETQYSTRIGVTAVNPATGEIY-SHRGDERFAMCSTFKAYASAAVLRKTE +DGSTSLDKTVVIDPGDLVENSPVTAAAVGTPMTLGQIAEAALTQSDNTAGNYLLREIGGP +QAITALARDVGDGSTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDAASRD +QLLEWMRASKTSDKRMRAGLPTGWTAGDKTGGGGFGTANDAGVAWSPDGAPVVLAILTDS +LTQDAQGNNQAIADTTAAVIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis circi TaxID=871959 RepID=UPI000E226E48 +---VQPDFAALEKAFDARLGVYAIDTGDGREV-AYHADERFAYASTHKVFNAAAILHRGD +----DLNRTVTIRQSDLVPNSPITEKHLGEQMPLQSVLDAALRYSDNTADNLMFREIGGP +AGLAAEVRRLGDTVTRVDRIEPALNETSPGDVRDTTTPRVWAKDLRAVALDSGLPADKQA +VLVKIMRANTTGANVIRAGVPADWQVADKTGSADYATRNDIAVVWPPNRAPIVLAVLSDH +AKKDAKTDDKLIAQAAAAVVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDEBCA7 +----EAELAALESRHPGRICVSILDMASGKRI-EHRARERILMCSTFKALAAALVLARVD +RGQEKLDRRIRYTKSDLVDGSPATKAHVRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP +KTLTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS +QLAAWLITNKTGDARLRTGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI +PAIAADERNGIVAEIGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. AT1 TaxID=574934 RepID=A0A150UFW0_9BRAD +------ELESYERESGGRIGVYAENLANGKKL-AWRADERFVMCSTFKASLAACVLARVD +HGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVADMCKAIVELSDNTCANLLLARIGGP +AVLTAFWRSLGDTTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVVGEALSPASRT +LLTEWMVNCKTGANRLRGGLPTSWTIGDKTGNNGKDASGDIAVAWPKPETPILITAYTQG +GTPNAAQIEAAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MZ03-48 TaxID=2593677 RepID=A0A553ZNQ4_9ACTN +----AHDLRQLEQKFSARLGVYAIDTGTGREV-AYRDGERFPFNSTFKALAAGEVLKQRT +--LSGMNEVVRYSQDDLVPNSPVTEKHVGAGMTLQALCDAAVRYSDNTAANLLFDKLGGP +KGLNAALKKLGDQVTRMERPEPLLSTWDPKSTRDTTTPRALTKDLRAYVLGKVLRPAERT +QLTTWLRTNTTGDTLIRAGVPKSWVVGDKTGMGSYGTRNDIAVLWPAHSSPIVVSILSSH +GAEDATPDDKLIAEAASVVAH-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis alba DSM 44262 TaxID=1125972 RepID=A0A229RV86_9PSEU +--AARTDFEQLERTFGARIGVYAVDTATGREV-AFRADERFAYASTHKVFTAGGVLQRTP +--LADLDRTVTYSEKDLVSNSPVTEKHVATGMPLRAVMDATLRYSDNTGGNLLFRELGGP +EGLNAVLRGIGDTTSHADRIEPELNDTFPGDQRDTSTPRALAVGLRAFALGTALPEDKRK +VLVDMMRANTTGDENIRAGVP-GWPVADKTGTAGYGTRNDIGVVWPPNRAPIVISVLTDR +TAKDAKIDNKLLAQATAAAVK-- +>[subseq from] Beta-lactamase n=2 Tax=Xenorhabdus nematophila TaxID=628 RepID=N1NRD4_XENNE +--QIIEKLSILEKNANGHLGAVLINTADHSTI-AYRADQRFPLCSTSKLMAVSALLKRSE +TNDHLLNQQAHYQQSDLVEYSPITEKHLKSGMTLGELSAATLQYSDNAAMNLILNQLGGP +HEVTKFARTLGDNSFRLDRKEPELNNVIPGDERDTSTPRAMADDLYHLVLGNALDATQRE +QLITWLKGNTTGAASIRAGVPEGWIVGDKTGRCDYGSTNDIAVIWPVNQPPLILVTYFTQ +PDKEASARPDVLAAAARIMTQH- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD5E19F +-hALEARLAELERRHGGRVGVAALNLSTGVRV-GHRADERFLMCSTFKALASAMVLARVD +KGVEKLDRRIGFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP +PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRPSRA +QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDTAVAWSPNRGAIVVASYCEI +PTISADERNAVVAEVGRIVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium sp. 3P27G6 TaxID=2502215 RepID=UPI0010F56C11 +------KIRRIEAKSGGRLGVACRISGTTVQF-GYRENELFPMCSTFKALMAALVLHRVD +GGIEQLDRAIKVPHDAIIANSPTTKKFAGGEMTVAQLCEAAVTVSDNGAANLLLASFGGP +PQLTAYLRSIGDTVTRLDRIEPELNESVPGDVRDTTSPLAMIEDYERLALGDSLSQKGKA +QFVDWLVANKTGDERIRAALPKGWKCGDKTGTGEKGSTNDAAVIWPASGNPILMSVYLTG +TKQNLAKRNATIASVSRVLVE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. AA4 TaxID=591158 RepID=D9V5K6_9ACTN +----QPDFAALEKAFDARLGVYAIDTGNGREV-AYHADDRFAYASTHKVFNAAAILHRGD +----DLARTVTIRQSDLVSNSPITEKHVGEQMSLQSVLDAALRYSDNTADNLMFREIGGP +AGLAAELRRLGDTVTHVDRIEPALNETSPGDVRDTTTPRAWAKDLRAVALDSGLPADKQA +VLTKIMRANTTGAHVIRAGVPADWQVADKTGSAEYATRNDIAVVWPPNRAPIVLAVLSDR +PRKDAKTDDKLIAQAAAAVVK-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000A2FB291 +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP +PAVTAFLRASGDTLSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A427CII7_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP +PAVTAFLRASGDTLSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD7C9AB +-hALEARLAELERRHGGRVGVAALNLSTGVRV-GHRADERFLMCSTFKALASAMVLARVD +KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP +PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA +QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDTAVAWSPNRGAIVVATYCEI +PTISADERNAVVGEVGRIVAE-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013DAD9CE +---TAKDFAALEMACAGRLGVTLLDTASGRRL-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVRDADLLTHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAMTLQRVVLGDVLQPASRQ +QLSDWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA +GAISNEQRAGVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=A0A5B8DS91_9ACTN +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RDGEFLSRRIFYTQADVEQGAPETGKNLANGMTVEELCKVSITASDNCAANLTLRELGGP +AAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLTAK +TEQDAVRDDALVADAARVLAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Azonexus fungiphilus TaxID=146940 RepID=A0A495WIR3_9RHOO +---FGARLAALEAAVGGRLGVFIIDTASGASV-GYRADERFMLLSSFKALAGACVLQRVD +AGRERLDRRIVFDRSVLLPWSPVTEKFADGRMTVGELCAATIATSDNAAANLILDSLGGP +AALTAFLRGSGDDVSRLDRREPELNQPAADPAFDTTTPRAMAATLQRLLLGDVLSPASRR +QLQDWLLACATGERRLKAGLPVGWRIGDKTGSSRS-DANDVGIVWPPGRPPLLVAAYLSG +SPAEPAAREACLAAVGKILAD-- +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium RIFCSPHIGHO2_12_FULL_41_10 TaxID=1802433 RepID=A0A1G3ZPT0_9BACT +--QTNSSFTELEASSGGHLGVSAINTANNKIV-QYHAEEHFPFQSTFKVMVVSAILKKSM +ADPQLLQQKVTYKKEDLLSWSPITEKHLTDGMTVSELCAAAIIFSDNAAVNLLINKLESP +QAVTAFARSIGDDQFSLEDREGNLNSA-PGDLRDTSTPAAMAKSLQKLALGNILGASQQK +QLVTWMTDCTTGYARIHAGVPIGWIVADKTGSGDYGITNDIGIIWPPNCPPIVIAIYFIQ +NKKDALRRDDVIASATKIILS-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=UPI00071E993B +-qTLAQRLAGIERRTRGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFILTAAVLQRVD +RGELSLQQRLPVRASDMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP +PGLTRFLRTLGDAQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDVLRPASRQ +CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG +AKVDEAARDAALKAVAVAV---- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00131FAB70 +-----GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKALQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] BKC/GPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Shinella kummerowiae TaxID=417745 RepID=UPI001323D018 +--TLEKRLAELEARHEGRLGVAILNFATGARL-GHRTDERFLMCSTFKALLAGHILARVD +REEEALDRRIVVKKSDLVDWAPVVEKRIGGDISIAELCEATITLSDNAAANLLLASSGGP +KAVTEFLRGFGDDITRLDRTEPTLNYDTPDDERDTTTPVAMIETLRKLIFGDVLSPRSKA +QLAAWLVMNKTGDTRLRAGFPADWMTGDKTGTNGAGNANDVAIAWSPNRGAIIVSAFVEM +PGISGDERNAVIAEVGRIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4U9P4P3_STEMA +-----GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKALQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Scopulibacillus darangshiensis TaxID=442528 RepID=A0A4R2NKL5_9BACL +----TEDFAKLEDKFDARLGIFALDTGTNQTV-TYRSDERFAYASTLKALTVGALLQQKS +--LADLNQTITYTQDDLVNYNPITKKHVDTGMTLKELCDAALRYSDNTAENLILKQLGGP +SSLKKSLRKIGDNVTNPENFEPKLNEVKPGETHDTSTPKALAESLKAFTIGDALPTKKRS +LLVDWLKRSTTGDTLIRAGVPKGWEVGDKSGGSSYGIRNDIAVIWPPKGDPIVLAILSNR +DKKDKGYNDKLIAQATKEVIN-- +>[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B5KLI1_STEMA +---AAADFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAMTLQRVMMGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013D94C73 +-----GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKALQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MMG1121 TaxID=1415544 RepID=A0A0M8V1S8_9ACTN +-----GELSELEQRHGARLGVFARNIRTGRTV-SYRAGERFAMCSTFKAFAAAAVLRDHG +-DCAPLDKVIPYPPHDILSNSPRTAEHVDTGMTVGDLCAAAIQYSDNTAGNLLLRQLGGP +AGLTRFFRSLGDGVSRLDRWETDLSSAIPADPRDTTTPEALGRSFERLALGRALARADRA +RFVGWLKGNTTSAARFGAGLPHDWVLADKTGTGDYGTANDVGVAWTTRGTPLLLTVLSAK +KAQDAPADEALVAEAARILA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. CWH03 TaxID=2705029 RepID=A0A6A0ANY0_9ACTN +------RLSELERTHSARLGVFARNTRTGRTV-AHRADELFPMCSVFKTPAVAAVLRDLD +RNGEFLGKRIHYTEQDTEEYAVITGRNLANGMTVEELCDAAIRYSDNAAANLLLRELGGP +SAVTGFCRSLGDDVTRLDRWEPGLNSAEPWRAEDTTDPRHIAETYSRLVLGDALAGPDRQ +RLTGWLLNNTTGTLRLRAGLPDDWTLGDKTGAGAYGTNNDVGIAWTPDGSPVVLAVLTTK +PQPDAAPDNELVARTAQLLAD-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00066B1B60 +-----GDFAALEKACAGRLGVTLLDTASSRRV-GHREDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Lysobacter capsici TaxID=435897 RepID=UPI00062749C6 +---WRTRLRDLEKHSGGRLGVAVLDTGNGERM-LWRENERFRMCSTFKYLLAAAILRQVE +LGKVALSQQVPITAADMISHAPFTQPLVGRSASVAQLCEATVTLSDNPAANLLYPLVGGP +QGLTRFLREIGDGVTRTDRTEPTLNSGAPDDPRDTSTPSAQIATMQRLLLGDALKESSRQ +QLIAWLVANKTGDKRLRAGLPAGVRVGDKTGSGDD-ATNDVAIVWPPGRAPLLIVSNLAT +AKLDGAGRDAVLASLARIASEHf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. WM6368 TaxID=1415554 RepID=UPI0006ADB087 +---VVARLRELEREYGARLGVYARDTATGRTV-AHRADELFPMCSVFKTLAVAAVLRDLD +HDGAHLAKRIHYTAQDVTDGGSVTERNIAGGLTVAQLCSAAIAQSDNLAGNLLLRELGGP +TAVTRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLAIGDALDSGDRE +QLNRWLLSNTTSADRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPLILSILSTL +PEPTAPRDNTLIARAAKLLAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. HC44 TaxID=2711217 RepID=UPI0013EBF68D +---FTGELKELERKFDARLGVYAVDTGTGREV-AYRDGERFGYHSTFKALEAGAVLRKYS +--LNGMNKVIKYSSDDLVANSPITEKHVESGMTLRELCDAAVRYSDNTAANLLFDALGGP +KGLEADLRKLGDKVTLMERIEPHLSNWVPGETRDTTTPRALAKDLRAYVLGDVLRKRERA +QLATWLKTNTTGNEVIRAGVPEGWVVGDKTGTGGYGARNDIAVVWPPDSAPIVMAVLTNR +GKAEDVHDNKLLAEAASVVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. NS-7484 TaxID=1834161 RepID=UPI0011539D9A +---VDDQIAELERRHNLLVGLYAENLDTGRRV-THRPDDMFAMCSTFKAYAVARVLQLVE +HGQLSLDHRVFVDPQAIVSNSPVTETHAGAEMTMGELCQAALQRSDNTAANLLLKAIGGP +AAVTEFARSVGDQRTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILTGDALSPRQRR +QLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAYGPDGQRILLVMLTRS +QADDAENQRAVIGELTALV---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q3V774_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQLASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Actinoplanes friuliensis DSM 7358 TaxID=1246995 RepID=U5VZZ5_9ACTN +----TRQFRDLERRFDARLGVHAVDTGTGRTV-GHRADEPFAHASTFKALLAAVLLRRLP +--DAGLRQLVRYTEADLLEWAPVTSKHVATGMTVEALLAAAVQYSDNTAANLLLDKVDGP +KGLERELRRIGDTTTDVSRTEPSLNEATPGDRRDTSTPRALGTDLREFVLGDTLPGPRRQ +KLTDLLLGNTTGDTCIRAGVPAGWKVGDKTGSAEYGTRNDIAVVWPPTGSPLVIAVQSDR +GVPDATTDDALIAEATRVAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia brasiliensis TaxID=37326 RepID=UPI0004A6EDA9 +---ATAELTALEQQYDAQLGLFAVDTGSAKTL-TNRADQRMPFLSTFKGLAAAALLKAHP +LATGYFDRVVHFTEADLVTYSPVTSTKVAEGMTIAQIADAAITQSDNTAGNLLLRELGGP +QGLTAFLRTLGDQVSRLDRWEPDLNTALPDDERDTTTPAALAADYRALVLGDALGAPERE +QLTTWLKANTTGDKRIRAGVPAGWTTGDKTGTGDYGMANDAAVTWPDGGAPLVIAIQTRK +STKAAEPSNDLVAAATRLVVEK- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. WAC05292 TaxID=2487418 RepID=A0A3R9WYE3_9ACTN +------ALRALEREYGARLGVYAWDTATGRTV-AHGADALFPQCSLFKTLAAAAVMQRFD +RDGEYLAKRIHYTQADVTRGGEITRRNIAAGLTVAELCSAAIAQSDNTAGNLLLEELGGP +AAITSFCRSLGDPVTRLDRWEPELNSAEPWVSTDTTSPRAIARTYARLVLGDALRPRHRE +LLTGWLLGNTTSKDRLRAGLPADWAVADKTGAGSYAVNNNAGIAWPPGRPPVVIAVLSTK +PEATAQREDSLVARAAALAVRKf +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCSS17_015 TaxID=2175666 RepID=A0A2W1QZ89_9MICO +---TERTFAALEAEHDARLGVVAVDTGSGASV-AHRAGERFAFASTAKVFIAATVLDDAT +--PGDLDAVVPIGQGDVLSYAPVTSQRVGVGMTVRDLLTAMVRSSDNTAANLLVARVGGP +AAVQSWLCGIGDGVTRVDRVEPDLNAAVPGDERDTTTPAQFAADLRTVLLGSALDPDDRT +LLVDLMLGTTTGAGTIRAGVPAGWAVADKTGTGSYGVRNDVGIVTPPGRDPVVLVVLTSH +DTADAEPDDALVAAATRTVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. ET3-3 TaxID=2675851 RepID=UPI0012FB7C0B +-----AAFRGLEQEHGARVGLFTIDTGTGKTL-GYRQDERFAFDSTFKGLACGALLHAHP +LATGFFGQVVHFTAADLVTYSPVTSTKVDTGMTVTELCEAAITRSDNTAGNQVLKLLGGP +GAVTTFLRSIGDQVTRMDRWEPDLNTNIPGDDRDTTTPAALADDYRKLVVGDTLGEPERT +QLTAWLLANTTGDARIRAGLPADWKTGDKTGAGDYGTANDVAVTWPAGGAPLVIVVLTTK +PDQAAAGDNPLVAAVAKEAV--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium japonicum TaxID=375 RepID=A0A1L3F2X3_BRAJP +------ELESYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARAD +RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLADTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVAGEALSPAART +QLTEWMVGCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPKNKGPILIAAYTQG +GTPNAAQIEAVFARVGRMVAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces thermolilacinus SPC6 TaxID=1306406 RepID=A0A1D3DN36_9ACTN +------LLRALELTHDARLGAFAYDTGTGRTV-AYRADERFPMASLFKTIAVAAVLRDLD +RDGEVLARRVHYTAQYVKDYSPVTEENVANGMTVAELCDATITRSDNAAGNLLLRELGGP +TSVTRFCRSIGDDVTRLDRWEPDLNSAEPWRVTDTTTPRAIGRTYGRLVLGNVLPAHDRE +RLTRWMLANQTSDERFRKGLPEDWLLADKTGGGGYGSNNNAGVAWPPGRPPVVLAVQTTR +FTPDATADNELVAEAARLLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Cohaesibacter haloalkalitolerans TaxID=1162980 RepID=UPI000E650250 +-qDLKQTITSWETRLGARIGVTLRATPSDSLF-AYKADQRFPMASTFKSLMCGAVLARVD +AGSVSLSDRVTYQADQLQSYSPITKDHVESGMDVADLCEAAITLSDNTAANLMLEKVDGP +AGLTTFLRTIGDETTRLDRWEPDLNEGIDGDPRDTTTPDAMTLSLSRLLFGETLQPASAG +QLRQWMIDDKVAGALIRPHLPEGWIIGDKTGTGGNGTRGIVAFLKKPDGEAYVTAIYVTA +TDADITLRNEAISDIGRAVIDE- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella variicola TaxID=244366 RepID=A0A649UHQ6_KLEVA +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASIAATLRKLLTAQHLSARSQQ +QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLR- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Allokutzneria albata TaxID=211114 RepID=UPI00069490E7 +------------------MGVFAIDTATGKTV-SHRENDRFAMASTFKAYAVAALLKRHG +--TEVLSKRVHFTQQEIVTYSPVTEKHVGTGMTVGELCGAAITKSDNTAGNQMLKLLGGP +GELTKFAKSIGDGTTRLDRWETELNTAIPGDERDTSTPKALGSAYRDLVVGDVLPPAERE +QLKKWLLTNTTGGERLRAGIPKEWSIGEKTGTGDYASANDVGVAWTEKGTPIAIAVLTTK +DTKDAKADNALLARTAKLIVE-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces sp. CNY228 TaxID=1169159 RepID=UPI000362D3F5 +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSCRIFYTQDDVAQGAPETGKNLANGMTVEELCEVSVTASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus opacus TaxID=37919 RepID=UPI0002F2160A +---LDATIAALEAQYSTRIGVTAVNPVTGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE +DGSTSLDKTVVIEPGDLVENSPVTAAAVGTPMTLGKIAEAALTQSDNTAGNYLLREIGGP +QAVTDFARVVGDESTRLDRWETELNTAFRDDPRDTTTPNGIAQGFRALLLGDALDTASRD +QLLEWMRASKTSDKRMRAGLPTGWTAADKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS +LTEGAQGNNQAIADTTAAVIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-2580 TaxID=1463841 RepID=UPI0004C5F839 +---VVRQLRALEREYGARLGAYALDTATGRTV-LYRADELFPMCSLFKTMAAAAVMRDLD +RDGEFLARRVHYTLDDVTAGGSVTERNIAGGLTVAELCSAAIAQSDNAAANLLLRELGGP +TAVTDFCRSVGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYGRLVLGDALAPRHRE +LLTRWLLANTTSGDRFRAGLPVDWVIGDKTGSGSYGTSNNVGIAWPPGRPPVVLSVLTTR +PEASAPRADALVAKAARTLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-104 TaxID=1609135 RepID=A0A0F4IJI2_9ACTN +---AARRLRALEREYGARVGAYARDTGTGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD +RDGEFLARRIHYTQGDVTAGGSVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP +TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE +LLTRWLVSNTTSDDRFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK +PDAAAPRENALVARAAEVLA--- +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SF31_9BACT +--KLTEVVQSEESALQARVGMAVFDANTGMTW-QYRGDERFPLNSTHKVFSCAAMLAKVD +GKHLSLDQSVSINRGMLVTYSPITEKSLSPKITLGKVCQAAVSYSDNTAANVVFDAIGGS +AGFNAYMRSIGDEQTRLDRKEPELNEATPGDVRDTTTPNAIVSSLRKILLGDVLSDPSRS +ELTQWMLDDQVAGALLRASLPSDWKIADKTGAGGYGSRSIVAVIWPPSKQPLVVGIYITQ +TKASMQASNQAIARIGAVL---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces thermolilacinus TaxID=285540 RepID=UPI0003C77446 +------LLRALELTHDARLGAFAYDTGTGRTV-AYRADERFPMASLFKTIAVAAVLRDLD +RDGEVLARRVHYTAQYVKDYSPVTEENVANGMTVAELCDATITRSDNAAGNLLLRELGGP +TSVTRFCRSIGDDVTRLDRWEPDLNSAEPWRVTDTTTPRAIGRTYGRLVLGNVLPAHDRE +RLTRWMLANQTSDERFRKGLPEDWLLADKTGGGGYGSNNNAGVAWPPGRPPVVLAVQTTR +FTPDATADNELVAEAARLLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004C190B7 +---HRRRFADLEREFDARLGVYALDTATGTTL-AHRADERFAFCSAFKALAAAAVLDGNP +--LSHLDKRVRYSRADLMKHAPVTARHVDTGMTIRQLCDAAIRYSDGTAGNLLLRDLGGP +DRLTAYARGLGDKVTRMDRVEPAITQATPGDPRDTSSPRAFGGTYQKIVIGDALPGRKRA +FLLDLLKRNATGAERIKAGLPRGWTIADKTGTGDHGTLNDIAVLWPPRSPPVLLAIMTSK +AAKDAPYDQALLAEAAEYVT--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A0K2IMW5_STEMA +-----GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia uniformis TaxID=53432 RepID=UPI0009FE5F05 +--ALDDQLLALERKFDARLGVYAVATGSGSAI-AHRADERFAFCSTFKGLAAAAVLARNP +--LSHLDTVVDYTDADLMKSAVITSRHVGTGMTIRDLCDAAVRYSDGTAGNLLLRDLGGP +AELTAYLRGLDDTVTRMDRIEPSITEATPGDPRDTTSPRAIGTDYRKIVLGDALPEERRA +FLRDLLERNLTGAQRIRAGLPADWRVADKTGTGDYGTLNDIAIAWPPDTAPLVISIMSSK +PTRDAEYNQALLAEAAEYV---- +>[subseq from] Beta-lactamase n=1 Tax=[Pseudomonas] geniculata N1 TaxID=1167641 RepID=A0A0L8A666_9GAMM +-----GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 76 TaxID=2035220 RepID=UPI000C195A8E +---AVRKLRDLERRHGTRLGVFGWNTVTGRTV-LHRANERFPLCSTSKTMAIGAVLRDLD +HDGTFLSKVIHYTQLDIDRAAPVTGQNLAHGMTVADLCGAAVSYSDNTAMNLLLAELGGP +AAVTRFCRSLGDTVTRLDRCEPELNSAEPWRVTDTTTPRAIGKTYARLALGNALDRADRT +RLTGWLLANTTGGKRLRAGLPEGWTVGDKTGTGRYGTTNDVGIAWPPGQGPIVMAVLSTR +PEPDAEADDAVIAETAALL---- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2W6JQC9_STEMA +---TANDFAALEMACAGRLGVTLLDTASGRRL-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVRDADLLTHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAMTLQRVVLGDVLQPASRQ +QLSDWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA +GAISNEQRAGVLAQVGRIA---- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. Root369 TaxID=1736523 RepID=A0A0Q6X7J8_9ACTN +--DVTARLRALEERYDARLGVFAHHLATKRSV-RFRAGERFPMCSLFKSLAAAAVLRDLD +RDGEVLARRIHYTEDDLVIGSDQTAARLAEGMTIAELAEVAITYSDNAAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWEPELNTAEPWRCTDTTSPYAIGRTYGRLVLGDALNRRDRE +LLTHWLLNNTTSVDRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTDAGDPIVLAVLSTM +PAQDAVRDDALVADAARAVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix espanaensis TaxID=103731 RepID=UPI0009FDC8A0 +-------WAGLERKFDARLGVYAVATGSGATF-AYRADERFAFCSTFKGLAAAAVLQRNP +--LAHLDTVVTYTDADLMKSSTITREHVATGMTIRDLCDAAVRYSDGTAGNLLVRDLGGP +AGLTAFLRGIGDGVTRADRTEPALTEAAPGDPRDTTSPRAIGTDYQRIVLGDVLPADKRA +FLRDLLERNTTGARRIRAGVPLGWVVADKTGTGEYGTVNDIGLGWQPNAAPLVIAVMSSK +TTTDAKYDEALIAEAAAQVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora sp. CB01950 TaxID=1703930 RepID=UPI0009FB799E +----AESFRWLEQHFGARLGVYVLDTGSGREV-AYRADERFAFASTFKALAAGALLRRAS +--DADLDKVVTYRQEDVLTWAPVTSEHVATGMTVRDLLAASLDYSDNTAANLVTDQLGGP +AALQQALRELGDPTTEVSRTEPGLNSATPGDTRDTSTPRALAADLRRYVLDDVLPAARRQ +LLTELMVANTTGGPYIRAGVPAGWKVGDRTGNAAYGTRNDIAVLWPDGGAPVVVAVLSDR +PRQDAASDDALIAQATGAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium paragordonae TaxID=1389713 RepID=A0A386U752_9MYCO +--DLTSRFTEIERRYQGRLGVYVPASGATPAI-AYRAEERFALCSTFKAPLVAAVLHQYP +--LSYLDQRVTFSKADISSPSPIAEQHIDTGMTVGEMCDAAIRYSDNTAANLLLNRIGGP +AGFTAYLRSLGDSTSRLDHAEPELNRDPPGDERDTTTPHAIAVTMQQLVLGDALPQDKRP +MLTDWMARNTTGGKRIRAAFPADWKVSDKTGSGDYGRANDVAVVWSPAGTPHVIAIYTDI +AGYDAQPNEAFVADAARIVAS-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QE52_STEMA +---AASDFAALEKACAERLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGTPWVLTAYLQA +GAISYDQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora arborensis TaxID=2116518 RepID=A0A318NJZ9_9ACTN +---QHSRLVELERRFDARLGVYALATGTGATI-AHRADERFAFCSTFKGLAAAAILHNHS +--MPHLETVVRYSRADLMKSAVITGQHVATGMTIRQLADAAVRYSDGTAGNLLLRDLGGP +AALTAYLRSLGDSVTQMDRIEPEIVSAIPGDPRDTTTPRAIGTDYQKIVLGDALPADKRE +FLKDLLIRNTTGARRIRAGLPTGWTVADKTGTGDYGTINDIAIVWPPGSAPLVISMMSSR +AAREADYDQALLAEATAYVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinoplanes sp. LAM7112 TaxID=2486853 RepID=UPI000FD7F720 +---VSREFGELERRFGARLGVYAVDTGTGRTV-SHRGNERFAYASTFKALLAAVLLRRLS +--DAELRRVVHYTEADLLEHAPITSKHVATGMPVEALIAAAVQYSDNTAANLLLAEIGGP +KGLQRELRKINDNTTVVSRTEPTLNGATPGDKRDTSTPRALGADLRKVVLGDVLPGPRRQ +KLADLLIGNTTGGPYIRTGVPAGWKVGDKTGAGGYGTRNDIAVVWPPTGSPLVIAVQSDR +GMPDAPSADSLIAEATKVVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces albus (strain ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 / NBRC 107858) TaxID=1081613 RepID=A0A0B5ESZ1_STRA4 +---QHKQLAALERKFGARLGLYALDTGTGATI-AHRADERFAFCSAFKALAAAAVLDRNP +--LSHLDTLVRYTEDDLMKHAPVTARHLDTGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +EELTAYARGLGDRVTRMDRTEPAITEATPGDPRDTSSPRAFGTSYRKILLGGALPTAKRA +FLRDLLERSTTGARRIRAGVPRGWTVADKTGTGDYGTLNDIGVLYPPKSAPLLLALMSSK +PAEDAAYQEELLAEATAYAV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces qinzhouensis TaxID=2599401 RepID=A0A5B8JH23_9ACTN +-----RAFAALEKEFAARLGVYAIDTGSGRTV-LHRPDERFAYASTCKALIAAAVLRKHS +--LREMRRRVSYGREVLQPHSPITERNVGKGMTLSELCDATVRYSDNAAANLLFDELGGP +RGLQTELRSVGDRITRCDRYEVELSDAVPGDLRDTSTARALATDLRTYVLGNVLPPEKRA +VLADWLKRNTTGDQVIRAGTPDGWQVGDKTGTGGYGTRNDIAIVWRPKAAPIAIAVLSRK +DVKGAKHQDALIARAAEVALKAf +>[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000BA29D59 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAE--------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus sp. E9 TaxID=1742575 RepID=A0A1E5K2K1_9BACI +----SEAFKKLEDEFDVKLGVFAIDTGSNKEI-NYQENDRFAYASTFKPLVVGAILQTKS +--DPELQEVIRYTEEDLVTYSPITEKHVDEGMTLLEISDAAIRYSDNTAANLLLEAIGGP +DELETKLRDIGDETIEVDRYETELNEATPGDIRDTSTPKAMANSLQQYVLEDVLDADRRE +ILTNMLINNTTGDALIRAGVPEGWTVGDKTGAGGYGTRNDIGIIWPEDNEPIVIAIMSSR +DVEDADYDDKLIEKATKVVVKE- +>[subseq from] Class A beta-lactamase n=1 Tax=Kibdelosporangium aridum TaxID=2030 RepID=A0A428ZKJ2_KIBAR +--------FELERKFDARLGVYAVATGSGVTI-AHRADEQFAFCSTFKGLATAAVLHRNP +--MAHLDTVVTYTEADLMKSSAITKRHVATGMKIRDLCDAAVRFSDGTAGNLLLRDIGGP +AQLTAYLRGLGDDVTRMDRIEPAITEAKPGDPRDTTTPRAIGTDYQRIVLGDALAADKRD +FLRDLLERNVTGAKRMRAGVPQGWRVADKTGTGDYGTLNDIGIVWPPAAPPLVVSIMSSK +SAADAKYDEAVIAEAAAYVVN-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonas translucens pv. translucens DSM 18974 TaxID=1261556 RepID=A0A1C3TRY2_XANCT +-qTLAQRLAGIERRTRGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFVLTAAVLQRVD +RGELSLQQRLPVRAADMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP +PGLTHFLRTLGDAQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRALLLGDVLRPASRQ +CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG +AKVDEAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. CA-126428 TaxID=2073158 RepID=UPI000CD039C6 +-----PDFAPLERNFDARLGVYALDTGSGREI-AHRADERFGYASTHKAFSAGAVLQRTG +--LDGLAKKLTYTRADLQPNSPVTEKHVTTGLSLREAIDAALRYSDNTAANLLFRELGGP +AGLAAALRGVGDTTTHVDRIEPGLNDLAPGDVRDTSTPRAMAGSLRAFALGPALPPEKQT +VLTDMMRANTTGAALIRAGAPAGWAVADKTGTGSYATRNDIAVVWPPERAAIVLIVMSSR +QAEKADHDDRLIAQAAKLALDAf +>[subseq from] Beta-lactamase class A n=1 Tax=Rhizobium hainanense TaxID=52131 RepID=A0A1C3VCN5_9RHIZ +----EARLAALEAKHRGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAAVVLARVD +KRKEKLDRRIHYAKSDLIDYSPATEPNAGENMTVGELCAAAVTLSDNTAANLLLASFGGP +GAITTFCRSLGDEITRLDRTEPTLNYDNPNDQRDTTTASAMLENLRRLLFTDVLTPASRS +QLAAWLITNKTGDTRLRAGLPMDWLVGDKTGTNGAGNANDIAVLWPANRAPIIVTAYCEI +PEIAADERNAIIAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI0004C5B381 +----HQRLSALERKYGARLGVYALATGTGATV-THRADERFAFCSTFKGMAAAAVLHRRP +--LSHMDTVVTYTEADLMKHSPVTGKHVATGMTLRQLCDAAVRFSDGTAGNLLLREIGGP +GALTAFVRGLGDTVTRMDRIEPAITEATPGDPRDTSSPRAFGTDYQKVVLGNVLAADRRA +FLRDLLERNATSAQRIRAAVPRGWTVANKTGTGDYGTLNDIAVVWPAKSSPLLISIMSSK +STKDAAYDQALIAEAAKYVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Lechevalieria deserti TaxID=531939 RepID=A0A316HWG9_9PSEU +---ISGKLRDLEQQHGARLGVFATDTGSGRTV-LHRADELFPMCSTFKTIAAAAILRRDH +-NGALLGKVIRYTQEDVTKYGPITGKNLANGMTVSALCEATITYSDNCAANLLLKELGGP +TAITRFSRSIGDPVTRLDRWEPDLNSAEPGRVTDTTSPRAIGQSYARLTLGHALNRTDAD +QLTKWLLANTTGGNRIRAGLPTAWRWGDKTGTGKYGTTNDVGIAFPPGRSPIVIAVLSTK +SVQDAPADEPLLAKTAELVAGTf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SceaMP-e96 TaxID=1100824 RepID=A0A1C6LMN3_9ACTN +---FASEFKKLERKYDARLGVYAVDTGTGREV-AYKDGERFSYNSTFKALAAGAVLRKHS +--PSAMNRVIKYSKDDLVATSPVSEKHVATGMSLSELCDAAVRYSDNTAANLLLEDLGGP +KRLEGVLKGIGDDVTRMERIEPKLSQWTPGDTRDTTTPRTLAKDLRAFVLGGVLDKGDRK +QLTKWLRTNTTGDEVIRAGMPKGWVVGDKTGAGTYGARDDIAVVWPPGRAPIAVAIMSNR +FKKDVDFDNKLIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Gracilibacillus boraciitolerans JCM 21714 TaxID=1298598 RepID=W4VPL9_9BACI +----EQEFEKLEKEFDVRLGVYAMDMGNNQVI-EYNSEERFAYSSTFKVLAAAILLKEND +--FKDLEKVITYNEDDLVTYSPVTEKHVDSGMTLLEISEAAIRKSDNTAGNLMLEALGGP +DKFKQALRDIGDDITEPARYETELNEFSPDSNKDTSTPKAMASSLKKVALDDFLPNDKRE +ILIDWMKGNATGDELIRAGKPDGWVVGDKSGAASYGTRNDIAIVWPPNREPIVIAVMSRR +DTEDAEYENELIAKTSEIILHSf +>[subseq from] Uncharacterized protein n=1 Tax=Streptomyces sp. WM6386 TaxID=1415558 RepID=A0A0F5VN12_9ACTN +--RVSERLRELEQRHGARLGVFARNLGTGRTV-RHRADELFPMCSLFKTLASAAVLRDLD +RDGEFLSRRIHYTDADLPKGSDKTREHLADGMTVAELAEVAITFSDNGAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWETELNSAEPWRITDTTSPYAIGRTYGRLVLGDALNRRDRE +LLTHWLLNNTTSGTRLRAGLPKTWTVADKTGGGSYGTNNNVGIAWTPEGTPLVLAVLTTM +PEQSAARDDLLVADTAKALAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6C8X6D0_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPVSRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGVPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ADI97-07 TaxID=1522762 RepID=A0A3N6GI37_9ACTN +--RTARAFRGLEREFDARLGVYAVDTGSGLSV-THRSDERFAYASTCKALLAGALLDAHP +--LRRLDRRVRYGPGDLVANSPVTEEHVRSGLSLRALCEAAIRFSDNTAANLLFRELGGP +GGLQDALVALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALAADLRAYVLGDVLAPDARA +LLTDWLRRNTTGDTLIRAGTPDGWVVGDKTGTGGYGTRNDIAVVWPPGSAPITIAVLSRR +AAHGAEPQDALVARAAGVAL--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00066B85BA +-----GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVSVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKALQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TAA486 TaxID=1298880 RepID=UPI0003FBC785 +--AVTGRLKKLEREHGARLGVFAHNTRTGRSV-AHRADERFPMCSTWKPLAVAALLKDRD +RGGDRLAEHIRYSRSDLEDHSPITGTNLADGMTVRQLCDATLRYSDNTAANLLLRELGGP +AAVTRFCRSVGDDVTRLDRWEPELNSAEPGNVRDTTSPRAVGRTYMRLALGDVLGRAERL +QLTDWLKGNTTGGEGLRAGLPEGWTLGERTGAGDYGTDNDVGVAWTADQVPIVLAVLTTK +RSADAEPDHPLIAKTARILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora aureofaciens TaxID=1894 RepID=UPI0005277F88 +----DGAFKDLELHFGARLGVYAVDTGSGREV-AYRSDERFAFASTIKSLLTGALLRTAS +--DQELDKVVTYRQDEVLTWAPITSRHVDTGMKVRDLAAAALEYSDNTAANLLMTELGGP +ETLQRTLRELGDPTTNVNRNEPTLNEATPGDPRDTSTPRAFAADLRRYVLGDVLTEDRRR +MLTDWMVGNTTGAPFIRAGVPVDWKIGDKTGNGGYGTRNDVAVAWPSGGSPVVLVMMSDR +GKADATSDDALIAEATKAVVT-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6ALA7_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKYLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKA---------- +----------------------- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. CC120223-11 TaxID=1378090 RepID=UPI000BCE81BD +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP +PAVTAFLRASGDTLSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNSEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Rhodococcus TaxID=192944 RepID=A0A149ZQJ9_9NOCA +---LDATIAALEAQYSTRIGVTAVNPVTGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE +DGSTSLDKSVVIEPGDLVENSPVTAAAVGTPMTLGKIAEAALTQSDNTAGNYLLREIGGP +QAVTDFARVVGDESTRLDRWETELNTAFRDDPRDTTTPNGIAQGFRALLLGDALDTASRD +QLLEWMRASKTSDKRMRAGLPTGWTAADKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS +LTEGAQGNNQAIADTTAAVIE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2BVL4_STRVZ +--RLASRFTALERKHGGRLGVYALATGTGATL-THRADERFAFCSTFKTLAAAAVVHHRP +--LDQLDKRVTYTAADVDSISPVTEKHIATGMTVGELCDAAIRYSDGTAGNLLMREIGGP +AGLTDYLRGLGDKVSRMDDHEPELNDVPPGDPRDTTTPRAVAADYRALVLGAALPDAKRA +LLAGWLGRNATGARRIRAGVPKGWRVADKTGTGNWGRANDIAVVRPPDADPLVLAVMTDR +PGRDTPPVNAFIAEAAKLVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Phytoactinopolyspora alkaliphila TaxID=1783498 RepID=UPI0013BC95C9 +---ADEEFAELENTYDARLGVYAVDTGANQEI-AYRADDRFGHASTFKALLCGVVLQENS +--IEDLDRVITYTSDDLVFHAPITEQHVETGLSIGELCEAAVRYSDNTATNLLLDEVGGP +SGLGRALQENGDDVISVDRYEIEMSSAVPGDTRDTSTARSIGTSLRTFVLDDALSGDKQA +LLTAWLVENTTGDDLIRAGLPDDWVVGDKTGNGGYGTRNDIAVAWPPGRDPIVIAVLSSR +DEEGAEHDDQLIADTAEIIAD-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. KCTC 12332 TaxID=1793721 RepID=A0A126NGE0_9GAMM +-----ADFATLEKTSGGRLGVCLWHPASGARY-GHRMDERFPMCSTVKFPLAAAILHRVD +AGKLSLDQRVAVRQGDIISHSPFTERHVGKDMTVRDLCRATLIISDNAAANLLLPLIDGP +AGLTAFLQAQGDRITVSARNEPELNHFAPGDPRDTTSPAAMAGNLQRFLLGDVLSPASRQ +QLADWLIDNQTGDARLRAGLPQGWRVGDKTGSNGQDTSNDIAALWPLGGAPWLLSCYLQG +SALDDDGRDGILRQVGELA---- +>[subseq from] class A beta-lactamase n=1 Tax=Xenorhabdus TaxID=626 RepID=UPI00069AE9B5 +---IIHQLSILEKNANGRLGVVLLDTSDHSII-SYRENERFPLCSTSKLMTVSAILQKNE +TNAHLLNQRVHYQQSDLVEYSPMTEKHLKEGMTLGELSAATLQYSDNTAMNLLLNQLNGS +HEVTRFARTIGDHYFRLDRREPELNTAIPGDDRDTSTPQAMAKSLYNLVLGTALATTQRE +QLTEWIKGNTTGGTSIRAGLPKNWIVGDKTGRCDYGTTNDIAVIWPPDRAPLVLVTYFTQ +PNKEASARPDVLAAATRIVT--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBD1_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLNQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPHDTTTPAAMAATLQRVVLGEVLQPVSRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID14478 TaxID=2706073 RepID=UPI0013DAE851 +---TARRFAALERRHGARLGVFAQNIRTGAVA-AHRADERFPMCSAFKTLAVAAVLRDLD +RDGRFLDRRIRYTQADVDRGAPVTGKNLAHGMTVAELCGAAISYSDNTAANLLLHELGGP +AAVTRFARSAGDRVTRLDRIEPELNSAEPGRSTDTTSPHAIGATYARLVLGDVLDPEDRV +RLSGWMFANTTSGKRFRAGLPDGWVLADKTGTGSYGTANDVGIAWTPGGDPVVLSVLTTK +PDQDAEPDDQLVARAAELIA--- +>[subseq from] Carbapenem-hydrolyzing enzyme n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A096ZH67_ENTCL +-----DEIKDLEKDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ +DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +NEKEAKHEDKVIAEASRIAID-- +>[subseq from] class A beta-lactamase n=1 Tax=Clostridium sporogenes TaxID=1509 RepID=UPI0013D83EA2 +--QCNSAFSQLESDYNVKLGIYAFDTEMNKEV-AYHADDRFAYCSTFKALAAGAVLKQDS +--LDELKQVVKYKKEDVLSYAPIAKDNVDKGMTIEEICNAAVRFSDNTAANLLFNHIGGP +SGFKSALNQLGDNVTQPARIEPELNEAMPGDIRDTSTPRQLATDLQAYTTGNILTDDKKR +ILIDWMTGNATGNTLIRAGAPDNWVVADKSGTGPYGTRNDIAIVMPPNKKPIIIAILSTH +HTKEAKYDDKLIAQVSKIVFDSf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. LamerLS-316 TaxID=1157630 RepID=A0A1C6MIX1_9ACTN +----EQAFGGLERKFDARVGVYAVDTGSGVTV-THRPDERFAYASTCKALMAGALLKTRP +--LPQLDRRVRYGPDDLVANSPVAERHVDTGLTLRELCEAAVRYSDNAAANLLFHELGGP +RGLRDALVALGDRTTRCDRIEPDLSEAAPGDVRDTSTPRALASDLRAYTLGGALGTDARA +VLNDWLERNTTGDALIRAGAPAGWVVGDKTGTGGYGTRNDIAVVRPPGSAPIVLAVLSRR +DTRGAEPQDALVAEAARVALDAf +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB13_STEMA +---TANDFAALEMACAGRLGVTLLDTASGRRL-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVRDADLLTHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAMTLQRVALGDVLQPASRQ +QLSDWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA +GAISNEQRAGVLAQVGRIA---- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00066BE8AA +---AASDFAALEKACAERLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGTPWVLTAYLQA +GAISYDQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDBA4A7 +----EAELAALESRHPGRICVSILDMASGTRI-EHRARERILMCSTFKALAAALVLARID +RGQEKLDRRIRYTKSDLVHGSPATKAHLRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP +KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS +QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI +PAIAADERNGIVAEIGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399) TaxID=479435 RepID=D2PTW6_KRIFD +-------FGKLEKKYGARLGVYAVDTGSGREI-AHRADERFAYASTFKALAAGAVLRKYT +--LQGMGKVVKYSESDLLANSPITEKHVATGMTLRELCDAAVRYSDNTASNLLFDALGGP +KGLDAVLAELGDNVTQMEQRELELSVWDPSNPRDTSTPRAFARNLRTFVLGDALRAPERA +QLTTWLRTNLTGAELIRAGMPKGWVVGDKTGTATYGGRNDIAVVWPPGRAPIVLAIFSNR +PAAEAEHDNRLLAEAARVVAAAy +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. MH181796 TaxID=2339228 RepID=UPI00129D1ECB +----ATDFATLEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRTSGDAVSRSDRLEPELNSFAKGDPRDTTTPGAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q9RBQ0_STEMA +----ATDFATLEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRTSGDAVSRSDRLEPELNSFAKGDPRDTTTPGAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. AA4 TaxID=1896961 RepID=A0A2K8LSX2_9PSEU +----QPDFAALEKAFDARLGVYAIDTGNGREV-AYHADDRFAYASTHKVFNAAAILHRGD +----DLARTVTIRQSDLVSNSPITEKHVGEQMSLQSVLDAALRYSDNTADNLMFREIGGP +AGLAAELRRLGDTVTHVDRIEPALNETSPGDVRDTTTPRAWAKDLRAVALDSGLPADKQA +VLTKIMRANTTGAHVIRAGVPADWQVADKTGSAEYATRNDIAVVWPPNRAPIVLAVLSDR +PRKDAKTDDKLIAQAAAAVVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Pyruvatibacter mobilis TaxID=1712261 RepID=UPI001371718B +--QLDADLAALEARHGGRLGVAILDPATGAAT-GHRADERFLLMSTFKALAAAFVLTRVE +NGDEQLDRRITHSEADLIPWSPVTKHHTGAPMTVAALCDAAVTWSDNTAANLLLESVGGP +ASLTAYLRGLGDDMTRLDRIEPALNHDGPDDIRDTTTPAAMAATLRTLLFTDALAPASRD +QLTAWLITSKTGGTRLRAGVPDTWLVGDKTGTNTEGAAADIGVIWPLGHGPLIIAAYCDM +PSLTGDARNAVFAEVARLAVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium betae TaxID=244734 RepID=A0A4Q1VDG1_9BRAD +------ELESYERESGGRIGLYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGKADLLEYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDATSRLDHNEPELNRSQPGDPHDTTTPVAMAGNLKRLVVSEALSAASRA +QLTEWMVGCKTGANRLRGGLPAAWTIGDKTGNNGKDASGDIAVAWPKPDRPILIAAYTQG +GTPTAAQIEAVFARIGRMVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. ASS1 TaxID=2282124 RepID=A0A4P6W2W3_9GAMM +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAASVLSQAE +RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPGSRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA +GAISNEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase n=2 Tax=Agreia sp. VKM Ac-1783 TaxID=1938889 RepID=A0A1Y6FDE4_9MICO +------AFAQLEQEFGARLGVYALDPATRAEV-SYRADERFAYASTFKALAAGILLKTVP +--DDQLDEIVSYDSSQLLPNSPVTEENVDEGMTLRAVAEAAVRFSDNTAGNIMLERLGGP +EGFTQALRELGDTTTSSDRIETELNSAIPGDVRDTTTPRAFALDLATLLTTDALGAAQQA +QLIDWMTGNATGAELIAAGLDAGWSVADKSGAGAYGTRNDIALLWPPSGSPIVLVVMSNR +STEDADYDNALIARAAEAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD9864D +-hALEARVAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD +KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGRP +PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA +QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDIAVAWSPNRGAIVVATYCEI +PTISADERNAVVAEVGRLVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 3213.3 TaxID=1855348 RepID=A0A1H5B107_9ACTN +---VSARLAALEEQHTARVGVFAHHLGTRTTV-VHRADELFPMCSVFKTLAAAAVLRDLD +RHGEVLYKVVHYTEADLVDGSDRTRARLADGMTVEQLADVAIRYSDNGAGNLLLRELGGP +TAVTRFARSLGDPVTRLDRWETELNSAEPDRITDTTSPRAIAGLYGRLVLGDALRRPDRD +RLTAWLLNNTTSAARFRAGLPASWTIADKTGSGDYGTANDVGIAWTEAGDPVVLAVLTTK +PTPDAPYDNQLVADTAELVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces silvensis TaxID=1765722 RepID=A0A0W7X578_9ACTN +----AQAFKQLERKFDARLGVYAVDTGTGREV-AYNDGRRFAYNSTFKALAAGAVLRKNT +--LAGMDRVVKYSKDDLLANSPVTEKHVDTGMSLRALCDAAVRYSDNTAANLLFDELGGP +KGLDAALERLGDHVTRVERIEPFLSRWVPGEKRDTSTPRTLAKDLRAYVLGDVLAEPQRA +LLTRWLKTNTTGDHVIRAGVPKNWVVGDKTGTGTYGARNDIAVVWRPDAAPLVVAILSHR +ADKDAAPDDRLIAESASVVAD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID5464 TaxID=2690293 RepID=A0A6B1KRL9_9ACTN +----TARLRELEREHTARLGVYARNMRTGRTV-AYRAGERFPIASVFKTLAAAAVLRDLD +RDGEFLARRIHYTQDCVTKYSPVTQENLATGMTVGELCDATIRFSDNAAGNLLLKELGGP +TAVTRFARSIGDGVTRLDRWEPDLNSAEPWRVTDTTSPRAIGLSYARLVLGDVLEPRDRA +RLTDWLLRNTTSTEKFRKGLPPEWLLADKTGQPEYGGAHDVGITWPPDGTPIVLSVLTMQ +PERDAPADNALVARTAALLA--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB41_STEMA +----ATDFAALEKACAGRLGVTVLDTASGRRI-GHRQDERFPLCSTFKTVLAATVLDQSR +RVPGLLDRRVPVREADLLSHAPVARRHAGKDLTVRDLCRATIITSDNTAANLLFDVVGGP +PAVTAFLRAQGDSVTRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRLVLGDALAPGARQ +QLADWLIDNETGDACLRAGLGARWRVGDKTGSNGEDARNDTAVLWPVGGAPWVITAYLQA +ADISNDQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Opitutaceae bacterium EW11 TaxID=2161865 RepID=A0A2T6DZZ5_9BACT +--ALSSLLSALEERCAGRLGVAVLDPQTGEWL-GWREDERFAMCSTFKLLLAASILQRVD +RGLERTDRSILVPPKPLLVTSPVTEQHAGERMPVGALCEAIVTRSDNTAANLLLETVGGP +DAVTRFARSIGDEVTRLDRPELALNEATPGDPRDTTTPRAMARNLETLLVKDLLAPASRE +QLIAWMVESRSGIAKLRSALPAGWRAGDKTGANGSTTSNDIAIAWRPDGRPLLIAAYLTE +CPGPEAKRASVLAETGRLVFS-- +>[subseq from] class A beta-lactamase n=1 Tax=Lentzea terrae TaxID=2200761 RepID=UPI000DD4453D +---ITGKLRDLERQHNARLGVFATDTGTGRTV-LHRADELFPMVSTFKTLVAAAILRRDH +-DGTLLNKVIRYTQDDCTKYAKITEKNLANGMTVSALCDATITYSDNCAANLLMRELGGP +TAITRFCRSIGDPVTRLDRWEPDLNSAEPGRVTDTTSPRAIGQSYARLTLGHALNRSDAD +QLTKWLLANTTGDHRIRAGLPAAWRWGDKTGTGKYGTTNDAGIAFPPGRAPIVIAVLSTK +SVPDAGADEPLVAKTAELVAGF- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces misionensis TaxID=67331 RepID=A0A5C6K2H4_9ACTN +------ELDDLERRFGVRLGVYARNVRTGRVL-AHRAGERFAHCSVFKAFAAAAVLRDHS +-GCAPLDKVVHYPPHALLPNSPRTEENQETGMTVADLCAAAIRYSDNTAGNLLLQQLGGP +AGLTRFFRSLGDRVSRQDRWEPELNTAVPGDLRDTTTPEAIATGIERLILGRALAPSDRE +RLVTWMKGNTTSGARFRAGLPEGWTLADKTGTGFYASAHDIGVAWTTRHTPVVLAVLSTG +NEKDAPVDEALIREAARIVAR-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A1D7YMN7_9ACTN +--AVEAELAELERRHGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDHG +-GCAPLDKVVHYPPHDILSNSQHTAEHVDTGMTVADLCAVAIQFSDNAAGNLLLREIGGP +AGLTRFFRSLGDRVSRLDRWETDLGSAIPGDLRDTTTPQALGGSFERLTLGRALAGADRE +RLVTWLKGNTTSAARFRDGLPRDWVLADKTGTGDYGTANDIGVAWTTRNTPVLLTVLSTK +SAQHAPADDALVAEAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Ruegeria sp. AU67 TaxID=2108530 RepID=UPI000D69E455 +--PLTETVQSWERRLDARIGLLLYDPSNEWEV-SYRADELFPMSSTFKTLLCGAVLAEVD +AGTESLSDHVTYQTTDLVDYSPVTSKHVETGMTVGALCEATMTISDNAAANLLLRRLDGP +AGLTEFLRTNGDDITRLDRWETALNEATPGDPRDTTTPRAILATLDRLLFGQALSPASSA +QLRQWMIDDQVANGLIRAHVPDGWTIGDKTGAGGHGSRAIVAFLQTSEPRTYLAAIYLTE +SDAPFPERNAVLSDIARAMIS-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. 278 TaxID=2479851 RepID=A0A3R8UDF4_9GAMM +-----ADFTALEKASGGRLGVTLLNTATGKRF-GHRQDERFPMCSTFKFVLAATVLHHAD +RGTLSLDRRLPVRAQDLLSHAPITKRHVGKDLTVRDLCRATMVTSDNPAANLLLGVIGGP +AGVTSFLRANGDAVTRNDRLEPEMNEFAADDPRDTTSPAAMAASLQRFVLGDVLQPASRL +QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGEDTTNDIAMLWPLGGTPWVLTTYLQG +ATVDDAGRNDVLRQAAVI----- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. Leaf113 TaxID=1736259 RepID=A0A0S9R7D0_9RHIZ +-----AAFEQIARDLGGRVGITVLDTGGGPSL-QLAADAAFPLCSTFKLLLAAAILARVE +AGQDQLDRRIAYTAADLDVYAPITGGALKEGMSVAALCAAAMVWSDNTAANLLLGALGGP +AALTAYCRSLGDSVTRLDRTEPDLNSAEPGDPRDTTRPAAMAATVRTILLGDALTPGSRA +RLEGWMTAARTGTKRLRAGLPGDWSVGDKTGSGAYGTANVVAILRPPARPPLIAALYLTG +STASAEARDAAHAAIGRVIATAy +>[subseq from] Beta-lactamase n=1 Tax=Gracilibacillus kekensis TaxID=1027249 RepID=A0A1M7QR65_9BACI +----DEEFSKLENEYDARLGVYALDTGNDQII-TYNSEERFAYASTFKVLAAALLLKQNN +--IQDLEEIVTYKEEDLVTYSPVTEQNVGAGMTLLELSEAAIRKSDNTAANLMLEALGGP +DRLKQALREMGDDITNPERYETELNDFTPGSNKDTSTPKAMATTLKHIVFDDFLPKDKRE +LLLNWMEGNATGDALIRAGQPEGWVVKDKSGAASYGTRNDIAVVYPPDREPIVIAIMSRR +DTEDAEYDDELVAQAAKIALN-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A3D4TPX1_9GAMM +-----TDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP +PAVTAFLRASGDPVSRSDRLEPELNTFAEGDPRDTTTPAAMATTLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA +GAISYEQRAVVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. BoFeN1 TaxID=1231053 RepID=A0A369VNV6_9BURK +--QWSDALAGIERAAQGRLGVAMLDTGSGLAL-GWRQHERFAMASTFKLVLAGWMLALVD +QGKERLDARVHYPVADVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP +VGFTAFVRSLGDGATRLDRTEPTLNEAAVGDPRDTTTPLAMLQTIRKLVLGGALTPASRA +WLQRWMVETTTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVLWPPSGAPVLVTCYLTR +STATPQQRDAAIAQVARAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 76 TaxID=2035220 RepID=A0A2G6XVF6_9ACTN +---AVRKLRDLERRHGTRLGVFGWNTVTGRTV-LHRANERFPLCSTSKTMAIGAVLRDLD +HDGTFLSKVIHYTQLDIDRAAPVTGQNLAHGMTVADLCGAAVSYSDNTAMNLLLAELGGP +AAVTRFCRSLGDTVTRLDRCEPELNSAEPWRVTDTTTPRAIGKTYARLALGNALDRADRT +RLTGWLLANTTGGKRLRAGLPEGWTVGDKTGTGRYGTTNDVGIAWPPGQGPIVMAVLSTR +PEPDAEADDAVIAETAALL---- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00115EEB57 +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RMPALLDRRVPVRDADLLSHAPVTRRHAGKDLTVRDLCRATLITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMATTLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGTPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Kosakonia cowanii TaxID=208223 RepID=A0A3R5YRI4_9ENTR +-------IARLEEKLHARIGIAVIDTASGKSV-SYRGDERFPLNSTHKALLCGALLSKVD +RGEFALSDTTQFSKETLVDYSPVTSKFVAPKMSWQQVCSAAISYSDNTAANLAAQKLGGP +QKITAFFAGLGDNVTRLNRKEPELNSAVPGDLQDTTTPLAVSRTLEKLTLGDALKPESRA +QLVQWMKDDKVADALLRASLPSGWKIGDKTGAGAHGSRSIISVVWPKKGQPIIVSVYITQ +TEATLAQSNDAIARIGKSIFE-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0007F0223E +----ATDFAALEKACAGRLGVTVLDTASGRRI-GHRQDERFPLCSTFKTVLAATVLDQSR +RVPGLLDRRVPVREADLLSHAPVARRHAGKDLTVRDLCRATIITSDNTAANLLFDVVGGP +PAVTAFLRAQGDSVTRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRLVLGDALAPGARQ +QLADWLIDNETGDACLRAGLGARWRVGDKTGSNGEDARNDTAVLWPMDGSPWVITAYLQA +ADISNDQRASVLAQVGRIA---- +>[subseq from] L2 family class A beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=UPI000C1534B6 +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RMPALLDRRVPVRDADLLSHAPVTRRHAGKDLTVRDLCRATLITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMATTLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGTPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Actinoplanes friuliensis TaxID=196914 RepID=UPI000427440E +----TRQFRDLERRFDARLGVHAVDTGTGRTV-GHRADEPFAHASTFKALLAAVLLRRLP +--DAGLRQLVRYTEADLLEWAPVTSKHVATGMTVEALLAAAVQYSDNTAANLLLDKVDGP +KGLERELRRIGDTTTDVSRTEPSLNEATPGDRRDTSTPRALGTDLREFVLGDTLPGPRRQ +KLTDLLLGNTTGDTCIRAGVPAGWKVGDKTGSAEYGTRNDIAVVWPPTGSPLVIAVQSDR +GVPDATTDDALIAEATRVAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Lentzea aerocolonigenes TaxID=68170 RepID=UPI0009DD2B2D +----TGKLRELERQHNARLGVFATDTGTGRTV-LHRADELFPMVSTFKTLVAAAILRRDQ +-DGSLLNKVIHYTEDDCIKYAKITEKNLANGMTVSALCDATITFSDNCAANLLMRELGGP +TAVTRFCRSIGDPVTRLDRWEPDLNSAEPGRVTDTTSPRAIGQSYARLTLGHALNRADAD +QLTKWLLANTTGDHRIRAGLPADWRWGDKTGTGKYGTTNDAGIAFPPGRSPIVVAVLSTK +PSKDAPADEPLLVEAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Photorhabdus luminescens subsp. sonorensis TaxID=1173677 RepID=A0A5C4RDH2_PHOLU +--RLATVVKQEEQTLNARIGVAVIDTASDKIV-SYRGNERFPLNSTFKALLCGVLLSEVD +KGKVALTDAIQFNKTELVEYSPVSEKFVAPAMNWQQLCSAAVSYSDNTAANLIAKKVGGP +AAMNLFFSGLGDSVTHLDRYEPELNSAIPGDERDTTTPVAVSQTLQKLTLGEVLKPSSRQ +QLVEWMRDDKVADALLRSVLPAGWKIADKTGAGDYGSRSIISIVWPKNSSPLIVAIYITQ +TEATIVQSNEAIARIGKIL---- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MMLR14_014 TaxID=1898744 RepID=A0A1S2JE75_9MICO +--ATARAFAALERRYDARLGVVAVDTGDGRTI-AHRAGERFAFASTIKVFIAAAVLDASS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP +HAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR +ADPGAEPSDALVAAATRTAV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. PCS3-D2 TaxID=1460244 RepID=A0A024YWM5_9ACTN +----VRRLRALEREYGARVGAYARDTRSGRTV-RYRANELFPMCSVFKTPAVAAVLRDLD +RDGGFLARRIHYTQEDVTSGGLVTGENVAGGLTVAELCSAAIAQSDNGAANLLLRELGGP +TAVTRFCRSLGDRTTRLDRWEPELNSAEPSRVTDTTTPRAIARTYGRLVLGDALVPRHRE +LLTRWLVSNTTSDERFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTR +PDAAAPHENALVAKAAEVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-2664 TaxID=1463842 RepID=UPI0004C62DD4 +---LAARLRELEQRHSARLGVFARNMRTGRTA-AYRADERFPMCSLFKTVAAAAVLRDLD +RDGDFLAERIRYTAQYVKRYSPCTGKNIENGMTVAELCAATICYSDNTAGNLLLRELGGP +TAVTRFCRSIGDGRTRLDRWEPELNSAEPWRVTDTTTARAIGGTYARLVLGDVLAPADRE +RLTGWLLANTTSDERFRAGLPADWILADKTGGGSYGGNNDVGIAWPPDGAPILMAVLTAK +QERDAPADHPLVAATAALLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces chartreusis NRRL 3882 TaxID=1079985 RepID=A0A2N9BJ55_STRCX +----TARLRELEREHTARLGVYARNMRTGRTV-AYRAGERFPIASVFKTLAAAAVLRDLD +RDGEFLARRIHYTQDCVTKYSPVTQENLATGMTVGELCDATIRFSDNAAGNLLLKELGGP +TAVTRFARSIGDGVTRLDRWEPDLNSAEPWRVTDTTSPRAIGLSYARLVLGDVLEPRDRA +RLTDWLLRNTTSTEKFRKGLPPEWLLADKTGQPEYGGAHDVGITWPPDGTPIVLSVLTMQ +PERDAPADNALVARTAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. 2A TaxID=2603816 RepID=UPI0013529C78 +----DPDITAIERRIGGRIGVAAGS-ADRILL-HHRADERFPMCSTFKVLEAAAVLARVD +AGSETLDAMVSYGAGDLLSYAPVTRKALAASLSVAELCAAALVWSDNTAANLLLARIGGP +AGLTAWLRGIGDPVTRLDRDEPTLNSALPGDPRDTTTPEAMRRTLGRILLGSLLAPPSRD +RLEAWMAGSQTGLKRLRAGLPRDWTIGDKTGSGDNGTVNDVAILQPPGRAPVTVAVYITG +STLPAAAVESAHAEIGRLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Methyloceanibacter sp. wino2 TaxID=2170729 RepID=UPI000D3EB9CA +--DLASQFAKIEKKIGGRLGVAVS--GDGLKA-AYHGGERFPMCSTFKLLVVAAVLHRVD +EGDEMLSREIPVPPDAILDYAPVAKEYAGGTMTISELCEAAMVWSDNTAANLILERLGGP +EAATAYVRSLGDTVTRIDRMEPDANVFGPGELRDTTTPEAMLGDLQKLFLGDALSPLSRD +RLTEWFVANQTGKDRLRAGLPPTWRVGDRTGTGPHGTSNDVAMAWGEDGRPILIAAFLTG +SKADAAARDNALADVGRAI---- +>[subseq from] class A beta-lactamase n=1 Tax=Belnapia sp. F-4-1 TaxID=1545443 RepID=UPI0009DDF586 +----AEGLATLEARQGGRLGVAILDTGSGRML-AHRGEERFALCSTFKHLAAARVLARVD +AGEERLDRHVAYGREALVPYSPTTGPGAEAGLGMGTICEAAVVLSDNTAANLMLDSFGGP +AGLTAWLRGLGDGVTRLDRREPELNVVPPGDERDTTTPLAMARTMQRLLLGEALSTDSRE +RLAGWLVGCRTGDARIRAGMPVGWRVGDKTGTGPAPPTNDVAIAWPPGRAPVIVAAYLEG +ARGSDAERSAVLAEVGRIAA--- +>[subseq from] Uncharacterized protein n=1 Tax=Streptomyces sp. B9173 TaxID=1462558 RepID=A0A1V9WJ87_9ACTN +---VTARLRDLEAAHGARLGVFAHNVRTRRTV-RYRADERFPVCSLFKTLAVAAVLRDLP +--EGTLDRRVYWTAADVVENSPVTQEHVADGLTVAELCAAAVQRSDNTAGNLLLREIGGP +AGLTRFARSVGDRVTRLDRWEPDLNSAEPDRVTDTTSPAAIGRTYGRLVLGDALAAGDRR +RLTDWMLGTVTSANRFRAGLPPTWTVADKTGGGWYGANNDAGVAWTPDGAPVVLVVQLTE +PDREAAYDHDLIVETAKVLAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Amycolatopsis sp. GLM-1 TaxID=2267691 RepID=A0A3R9DPR4_9PSEU +------DFAPLEREFDARLGVYAIDTGSGREI-AHRADERFGYASTHKAFSTAAVLQRTS +--MAGLAKVLPYTSADVQPNSPVGEKHVGTGLSLRDAIDAALRYSDNTAANLLFRELGGP +AGLAAALRGIGDTTTHVDRIEPGLNDLAPGDIRDTSTPRAMAADLRAFALGTALPAEQRT +FYTDTMRANRTGDAVIRAGTPAGWTVADKTGTGAYATRNDIAVVWPPGRAPIVLAVMSDR +KTADAEHDDRLIAQAAKLTLDTy +>[subseq from] class A beta-lactamase n=1 Tax=Roseovarius sp. TM1035 TaxID=391613 RepID=UPI000319945E +--HLAATIDRIEQELDARVGVVIRDSGSDWTV-SHRAEERFLMASTFKTMLCGAVLHRVD +EGDLDLEERIAIEAAEVLEYAPVTEKMVGETMSVGELCHAALDMSDNTATNLLIDRIEGP +QSVTAFLREIGDPVSRLDRREPDVNTFAPDDPRDTTTPEAMVSTMETLLTGGALSPQSRA +QLVDWMTDGGVTGALIRASTPAGWHVADRSGSGNF-NRNIVAMVTPPDREPYFIAIFLSD +ADADFNTRNGAVIELSKAVMQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003694502 +--DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTYKALAAAEVLDATT +--DAELDQVVRYSADDLVDYSPITKQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEQELKGIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD +ILNAWLRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSTR +DEPDASFDNALIVEAAEEVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella cf. planticola B43 TaxID=95610 RepID=UPI0003451541 +-------IARLEEKLHARIGIAVIDTASGKSV-SYRGDERFPLNSTHKALLCGALLSKVD +RGEFALSDTTQFSKETLVDYSPVTSKFVAPKMSWQQVCSAAISYSDNTAANLVAQKLGGP +QKVTAWFADLGDNVTRLDRKEPELNSAVPGDLQDTTTPLAVSHTLEKLTLGDALKPESRA +QLVQWMKDDNVADALLRASLPSGWKIGDKSGAGAHGSRSIISVVWPKKGQPIIVSVYITQ +TEATLAQSNDAIARIGKSIFE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas lactitubi TaxID=2045214 RepID=A0A2M9QZ47_9GAMM +----ASDFAALEKACSGRLGVTLLDTGSGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDPALLDQRLPVRAQDILEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRASGDTITRSDRLEPELNSFAIDDPRDTTTPAAIAATLQRLVLGDALKPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWIVTAYLQA +GALSFEQRAAVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFB25EA +----NDSFAKLEKEFDAKLGIYALDTGTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYNREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPQLNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +D---------------------- +>[subseq from] Beta-lactamase n=1 Tax=Desertiactinospora gelatinilytica TaxID=2666298 RepID=A0A2W2GP79_9ACTN +--AVRRELRALEASFDGRIGAYAIDTATGRTV-GHRAGERFPLASTFKAVVAAAVLHKAR +TDPGLLKRVVRWAAAEVEPYSPTTQKHVKSGLTIGRLCEAAITQSDNTAGNILLKEIGGP +AGLTRYFRSLGDEVSRSDRWEPEMNRWKPGEKRDTTSPAAMAHGFRRLTAGDALNAKDQA +RFNAWLLANKTGGDRIRAGLPSTWKVGDKTGTGGYGTANDVAVIWPAKAAPIVMAVYTSR +KAAEADAEEEVLAKTAAILVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-350 TaxID=1463902 RepID=UPI00068B7F34 +------LLAALEQEHAARLGVYARNLTTGRTV-RYRADEPFPICSVFKTVAVAAVLRDLD +RDGEFLARRIRYTQADIDRGAPVTGENLANGMTVAQLCAAAIDHSDNTAANLLLHELGGP +TAVTRFCRSIGDGVTRLDRWEPELNSAEPDRRTDTTSPRAIARTYERLALGRALPPAKRD +QLLAWLRANTTSTHRFREGLPQDWALADKTGTGSYGTTNDVGIAWTPAGAPVLLAVLATK +PTPAAPKDEPLVARTAALLA--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis flavescens TaxID=758803 RepID=A0A1M6BSH8_9ACTN +------GFAALETEYGARLGVYALDTGTGEEV-EYRADERFAYASTHKALSAGALLAENS +--LEEMEEVVTYTEEDLVDYSPVTEQHVDTGMTLMEVIDASVRYSDNTAANLTLDALGGI +EGFTEDLRSIGDDVTEPARYETELNEATPGDIRDTSTPRAMATSLEAYTLGDVLPEEKQD +VLIDLLIRNTTGDETIRAGVPEGWIVGDKTGSAGYGGRNDIAVVWPEEGDPILISVYTAQ +DAENAEPINEIIADATEIVVDE- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. gb1(2016) TaxID=1828321 RepID=A0A652LDV4_9ACTN +----EQAFGELEQKFDARAGVYAVDTGSGLTV-THRPDERFAYASTCKALLAGALLKTYT +--LPQLDRRVRYGPGDLVANSPVTEQHVDTGLTVRELCDAAVRHSDNAAANLLFQELGGP +GGLRDALVALGDRTTRCDRIEPDLSEAAPGDVRDTSTPRALAADLRAYALGSALGTDARA +VLNDWLERNTTGDALIRAGAPAGWVVGDKTGTGGYGTRNDIAVVRPPGSAPIVLAVLSRR +DARDAEPQDALVAGAARVALDAf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TP-A0874 TaxID=549819 RepID=UPI000853640D +------RFRRLEREFHARLGVYAVDTGTGRKI-EHRSDERFAMCSTFKTYAAASLLRSHS +LSGPFFDRRVRIEEADLVDNSPITEARLGERMTVAELCGAAITHSDNTAGNHLLRLQGGP +GAVTRFARSIGDRATRLDRWETELNSALRGDRRDTTTPAAIGEGYRTIALGSVLPAAERK +QLISWLKANTTGDERIRAGLPDGWITGDKTGAGSFGTLNDVAVAWPADADPIVIALLSDR +SKVDAVPDNALLADAAQAVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Modestobacter versicolor TaxID=429133 RepID=A0A323V4M9_9ACTN +--AVEEALAALEAEFGVRLGVHAVDTGSGEVV-EHRADEPFPYASTYKALAAGAVLDRTT +--PAQLDEVVTWTAADLVTYSPVTELHVGTGLPLRDVLAAALQVSDNTAGNVLFDQLGGT +EGFEEELRALGDTATSAERYEPELNTAVPGDARDTSTPRALATDLQALAVGDALEAEDRE +LLLGWMRTATTGTGLVRAGVPAGWEVADKSGTAAYGTRNDIAVVQPPGRAPIVLAVLSTH +PAADAEPSDEVVARAAAVVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseoflavus TaxID=35619 RepID=A0A0L8NMG8_9ACTN +-----PRLAALERKYDARLGVYALATGTGATV-THRADERFAFCSTFKGMAAAAVLHRHP +--LSYVNTVVTYTEADLMKHSPVTRKHVATGMTIRQLCDAAARFSDGTAGNLLLREIGGP +GELTAFTRGLGDTVTRMDRIEPAITEATPGDPRDTTSPRAFGTDYRKVVLGNVLAADKRA +FLRDLLERNTTGARRIRAAVPRGWTVADKTGTGDYGTLNDIAVVWPAKSPPLLISIMSSK +STKDAAYDQALIADAAAYVVD-- +>[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobium sp. Ghvi TaxID=1855319 RepID=A0A1I5CIP8_9BRAD +------ELDSYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEDKLAAMISYDKADLLEYAPVAKQNLAAGMSIADMCKAIVELSDNTCANLLLAHVGGP +TALTGFWRSIGDTTSRLDHNEPELNRSPPGNPHDTTTPAAMAANLKRLVTGEVLSTASKT +QLTEWMVNCKTGANRLRGGLPAAWKIGDKTGNNGKDASGDIAVAWPKPDAPILIAAYTQG +GMPSAAQLEAVFARIGRMVAE-- +>[subseq from] BlaIMI-2 n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1I9W1Y6_ECOLX +-----DEIKNLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ +DNQLNLNQIVNYNTRSLEFYSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +NEKEAKHEDKVIAEASRIAID-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces aurantiacus TaxID=47760 RepID=UPI0006E3F741 +-----GALAELEHAHSARLGVFARNTVTGKAV-RYRADETFPMCSVFKTLAAAAVLRDLD +RRGEFLDLRIRYTDQDLTDGSPVTGENLANGMTVAALCHAAVTRSDNAAANLLLRELGGP +TAITRFCRSIGDTTTRLDRWEPALNSAEPWRTTDLTSPAAIGRTYAKLVLGDALVPRDRR +QLTEWLLANTTSTDRFRAGLPADWALGDKTGTGEYGTTNDVGIAWTPERSPVVLAVLSTT +SDPDAPMDNALVAEAAELLA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000312778C +----AKDFAALEAASGGRLGVTLFNTGTGWRT-GNRQDERFPMCSTFKFVLSAAVLHLAD +QGTLPLDRRIPVRQQDMLSHAPVTTRHIGKDVTVRDLCRATMITSDNPAANLLLGVVGGP +AGVTAFLRANGDAVTRNDRLEPEMNRFTPGDPRDTTSPAAMAASLQRFVLGDVLKPASRQ +QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ATVDDAGRNDVLRQVAVI----- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q3V776_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDALSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLIAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SC18_KLEPN +--------------FRAAIGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIICRD +KN--------------------- +>[subseq from] Beta-lactamase n=2 Tax=Rhodococcus TaxID=1827 RepID=Q0SKC3_RHOJR +--SLDATIDALEAQYSTRIGVTAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE +DGSTSLDKTVVIEPGDLVENSPVTAAAVGAPMTLGQIAEAALTQSDNTAGNYLLREIGGP +QAITALARDVGDGGTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD +QLLEWMRASKTSDKRMRAGLPTGWTAADKTGGGGFGTANDAGVAWSPDGAPLVLAILTDS +LTQDAQGNNQAIADTTAAVIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces triticisoli TaxID=2182797 RepID=UPI000DDBACDB +-kEITGQLRNLERAHSARLGVFAQDPATGRTV-LYRARELFPMCSTFKTIAVAAVLRDLD +RDGTFLAELIRYTDKDVTEYAPITGDNLAGGMTVADLCAAAIDHSDNAAANLLLRELGGP +SAVTRFCRSIGDSVTRLDRWEPDLNSAEPGRVTDTSSPLALGRTYSRLILGDALEEADRD +RLTLWLLNNTTSGNRFRAGLPKDWTVADKTGTGNYGTTNDVGIAWPPGQGPVVLAVLSTK +HDSAAPADESLVADTAALVA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. CCGE-LA001 TaxID=1223566 RepID=A0A120HP83_9BRAD +------EFEAYERESGGRIGLHAENLASGAKL-VWRADERFVMCSTFKASLAACVLARAD +RGEEQLAAMIPYREADLLEYAPAARQNLTAGMSVREMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSIGDTTSRLDHNEPELNRSRPGDPRDTSTPAAMAGNLRRLVLAEALSPASRA +QLTDWMVNCKTGANRLRGGLPASWKIGDKTGYNGKDAAGDIAVVWPKPDTPILITAYVQG +GTPSAAQIAAVFARIGRMVAD-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A0N0TUG9_9ACTN +---HRRAFRALENAFDARLGVYAIDTGTGREI-AYRDGERFPYASTFKALAAGAVLREER +--LSGMERVVRYTKDELVDPSPVTEKHVDTGMTLDALADAAVRHSDNTAGNLLFEELGGP +KGLQAVLRSLGDDVTRMDRIEPELGDWRPGEVRDTSSPRALARDLRAFVLGDVLRAPERE +RLTTWLKTNLTGDETIRAGVPDAWVVGDKTGTATYGGRNDMAVVWPPDGAPIVMAILSTR +SDREARPDNRLIARAASVVAE-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013EE3F4B +----ASDFAALEKACSGRLGVTLLDTGSGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDPALLDRRLPVRAQDILEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRATGDTITRSDRLEPELNSFALDDPRDTTTPAAIAATLRRLVLGDALKPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVMWPVGGSPWIVTAYLQA +GAISFEQRAAVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium holsaticum TaxID=152142 RepID=A0A1E3RVX9_9MYCO +---IQDQIAALEHQHGALIGVFAVNLASGNTV-AHRAQERFAMCSTFKAYAAARVLQMAE +HGELSLEERVFVDPDDIVANSPVTEARAGGEASLAELCRAALQRSDNTAANLLLTRIGGP +QAITAFARSIGDPQSRLDRWETELNSAIPGDLRDTSTPEALGGGYRNLLAGDVLAPPQRS +QLEDWMRANQT--SSMRAGLPQGWTSADKTGSGDYGSTNDVGIAYGPDGQRILLALMTRS +QASDAAGLRPLIGEVARLVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-1824 TaxID=1463889 RepID=UPI00099BD3F1 +---AARELRALEREHSARLGAYAHDTATGRTV-VYRPDERFPMCSLFKTVGAAAVLRDLD +RDGEFLARRIRYTAQYVEANSPITGRNLSRGMTVADLCAYSITHSDNTAANLLLRELGGP +GAVTRFCRSIGDPVTRLDRWEPELNSAEPWRETDTTTPRAVGRTYARLVLGDALVPCDRR +LLTGWLLANTTSGERFRAGLPADWTVADKTGGGSYGGNNDAGIAWPPGRPPVVLAVMTTK +PDRDAPADNPLVARTAGVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. lig30 TaxID=1192124 RepID=A0A063BBE2_9BURK +--AAQTALAALEQASNGRLGVVALDTATGARI-AHRPRERFPMCGTFAVVVAAALLARAA +LDPSLMSRRVLYRRYDMVPESPVTKNRVDAGMTTEELCAAALQYGDRSAANLLLDLLGGP +RSATAFAHSIGDTAFRLDRWEPELNAATPGDERDTTTPLAMAGTLRRLLVGDALGAAQRA +QLKTWMLGNTMGAAGIRAGVPPDWQVADTTGAGDYGTTNGVAVAWPPSRAPLALAIYFTQ +PGGDARARDDVVAAAVRIVAEVf +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. 4(2017) TaxID=1404402 RepID=UPI0014087D58 +------ELESYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARAD +RGEEQRAAMIPYGKADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVVGEALSPASRT +QLTEWMVGCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPKNKVPILIAAYTQG +GRPNAAQIEAVFARVGRMVAE-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000C161610 +----ATDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA +GAISYEQQAVVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB78_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA +GAISYEQQAVVLAQVGRIA---- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A3D9IYT3_9ACTN +-----TELRDLERRYGARLGVYARNARTGRTV-AYRAGERFAMCSTFKAFAAAAVLRDHG +-DCAPLDRVVHYPPRDILANSPKTEEHLSTGMPVGDLCAAAIQYSDNAAGNLLLRQIGGP +DGLTRFFRSLGDGVSRLDRWEPDLNTAVPGDPRDTTTAEALGRGFERLTLGRALDEAGRA +LLVAWLKGNTTSARRFRAGLPQGWVIGDKTGTGDYATAHDLGVAWTTRNTPILLTVLSAK +AAKDAPVDEALIAEAARVLA--- +>[subseq from] Beta-lactamase IMI-3 n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0P0G279_9BACT +-----DEIKNLETDFNGRVGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ +DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILSEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +NEKEAKHEDKVIAEASRIAID-- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBA15_007 TaxID=1898735 RepID=UPI0009F31BB5 +--ATARAFASLERRYDARLGITAVDTGSGRTL-VHRAGERFAFASTVKVFIAAAVLDASS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTSVDRVEPDLNQATPGDRRDTTTPERFAADLRAVLLGDVLDAADRR +VLRDAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSR +ADAAAEPSDALVAAATRAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SBT349 TaxID=1580539 RepID=UPI00066D16F8 +--STDRAFGELEREFDARLGVYALDTGTGREV-AHQADERFAYASTFKALAVGALLQEYG +--LDGIEEVITYASDELIDNSPVTENFVETGMSLRELCAATLWYSDNTAANLLFEALGGP +DGLEAALEELGDDVTEMDRYEPELSEGTPGDIRDTSTPRAMAGSLRAFLLGDALERDERE +LLRQWMVTNTTGETLINAGVPDGWTVADKSGTAGYGGRNDIAVVWPDDGDPIVMAVMSSR +DEQGAERRDELIAEAATAAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium canariense TaxID=255045 RepID=UPI000A198F00 +--DAQPELETYERESGGRIGVYAENLATGARL-AWRADERFVMCSTFKASLAACVLARVD +RGEDQLAAMIPYGKADLLEYAPVAKQNIAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTASRLDHNEPELNRSPLGDPRDTTTPAAMAGNLRRLLTGEALSATSRA +QLTEWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKDTAPILIATYTQG +GTPSAAQIEAVFARIGRIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. LM091 TaxID=1904944 RepID=A0A1D8Y7V7_9GAMM +----AKDFAALEVASGGRLGVTLLNTGTGWRT-GNRQDERFPMCSTFKFVLSAAVLHLAE +QGRLSLDQRIPVRQQDMLSHAPVTTRHIGKDVTVRDLCRATMITSDNPAANLLLGVVGGP +AGVTAFLRANGDAVTRNDRLEPEVNRFTPGDPRDTTSPAAMAASLQRFVLGDVLKPASRQ +QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ATVDDAGRNDVLRQVAVI----- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase IMI-18 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A3Q9WYR0_ENTCL +------DIKNLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKRSQ +DNQLSLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTIALGNILSEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +YEKEAKHEDKVIAEASRIAID-- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCSS17_006 TaxID=2175642 RepID=A0A2W1PWX2_9MICO +--ATARAFAALERRYDARLGIAAVDTGSGRTI-VHRAGERFAFASTVKVFIAAAVLDASS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVCELVDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTRVDRVEPDLNEATPGDPRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR +ADPGAEPSDALVAAATRTAV--- +>[subseq from] Beta-lactamase IMI-8 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A0A7ERS0_ENTCL +---AMDEIKKLETGFGGRVGVYALDTGSGKSF-SYRANERFPLCSSFKGFLAAAVLKGSQ +DNQLNINEIVNYNKRSLEPHSPITQKYKENGMSLGDMAAAALQYSDNGAANIILERIGGP +EGMTNFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVGKSLKNLALGNILNDHEKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGTCGYGTANDYAVVWPKNRAPLIISVYTTK +SEKEAKHDEKVIEEASRIAITH- +>[subseq from] class A beta-lactamase n=2 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=UPI00071BFE15 +--TLAQRLAGIERRTGGRLGVTLLD-GSGAVLgGQRQDERFPMCSTFKFVLAAAVLQRVD +RGELSLQRPVQIRAVDMLSHAPVTERHVGGALSVAELCRATMIFSDNPAANLLFPLVGDP +PGLTRFLRELGDPVTRSDRHEPEMNLFAAGDPRDTTTPAAMAATLRTLLLGDVLRPASRQ +CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG +AKVDEAARDAALKAVAVAV---- +>[subseq from] Uncharacterized protein n=1 Tax=Chromobacterium sp. Panama TaxID=2161826 RepID=A0A2T5NIC2_9NEIS +----ARQLAELERNAGGRIGVFAQEADSGRTL-AYRADERFPMCSTFTLLLVGALLQRSA +TQPDLLYRHVGYRREQLIDYSPIAEQYVEQGMSVKDLCDAAMRFGDNTAANLLLEQLGGP +QEVTRFARSLGDGLSRLDRVEPELNRAEPDDPRDTTTPAAMTANLRALLFSPLLPERQRG +LLNDWLLGNTTGNLRIRAGLPAEWRVGDKTGSGGHGAANNVAVAWRPGKSPLLLSVYYWG +STAMMDERNAVIAAVARVAAAEf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces neyagawaensis TaxID=42238 RepID=UPI0006E43496 +-------LRALEEQYGARLGVYAHNVRTGETI-RHRADTLFPICSLFKTLAAAAVLRDLD +RDGEVLARRIHYTAADLLENSDVTRDHLATGMTIAELCDATIRHSDNTAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSGEPWRITDTTSPRAIGRTYARLVLGDALTRPDRA +LLTHWLLHNETSKTRMRAGLPSSWAVADKTGGGSYGTNNNVGIAWTEDGTPLVFSLMSRK +FDQDAATENKLIADTAHLLAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD7BCC0 +----EAQLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD +KGEEKLDRRIHYKKSDLIDYSPATEPNAGENMTVGELCAAAVTLSDNTAANLLLASFGDP +GAITTFCRSIGDEITRLDRTEPTLNYDTPNDERDTTTASAMLENLQRLLFTNVLTPASRS +QLAAWLITNKTGDARLRAGLPKDWLVGDKTGTNGHGNANDIAVLWPTKRAPIIVTAYCEI +PAIAADERNAIIGEIGRIAA--- +>[subseq from] Beta-lactamase n=2 Tax=Kalamiella piersonii TaxID=2364647 RepID=A0A3A9IPK2_9GAMM +---LATVAKQEEQALKARIGIAVIDTATGSVA-RYRGDERFPLNSTHKALLCGALLSQQD +KGRLMLSERTQFDRAALVTWSPVTEKSVAPAMSWQQLCHAAIAYSDNTAANLIAKKLGGQ +AAVTRFFADLGDKVTRLDRFEPELNSAIPGDMRDTTTPVAVSETLQKLTLGEALKPASRA +QLVQWMRDDRVAGALLRSVLPAGWSIADKTGAGEYGSRSIISVVWSENGKPVIIAIYVTQ +TEATLAQSNAAIARIGKAIF--- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf117 TaxID=1736260 RepID=UPI0006F62456 +-----AALEQIARDLGGRVGVTVLDTGGGPSL-QLAADAAFPLCSTFKLLLAAAILARVE +AGQDQLDRRIAYTAADLDVYAPITGGALKEGMSVAALCAAAMVWSDNTAANLLLEALGGP +AALTAYCRSLGDSVTRLDRTEPDLNSAEPGDPRDTTRPAAMAATVRTILLGDALTPGSRA +RLEGWMTAARTGTMRLRAGLPGDWGVGDKTGSGAYGTANVVAILRPPARPPLIAALYLTG +STASAEARDAAHAAIGRVIATAy +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Actinopolyspora TaxID=2639451 RepID=UPI0013F67952 +--EAKDRFAGLEQRFDARLGVYAVDTATGEEV-THRADERFAHASTYKALSAGVVLRRNS +--IGGLNRRIHYSRSDLVTYSPITKKHVDTGMTLRAVLDAAIRYSDNTAANLLFREIGGP +AALQAALRGIGDTTIHVDRTEPELNRRAPDDIRDTSTPRAMAETLWKFTVGDVLAPDKRA +ILNEMLRTAKLTGDLVRAGVPSGWEVGDKSGAAEYGTRNDIAVIRPPGRAPIVLAVMSDR +QSRDAEYDDALIAQAARQVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Nitrincola sp. A-D6 TaxID=1545442 RepID=A0A099PGZ6_9GAMM +---LLSELKRIENHLDARIGFAAHDTETGMRW-EYNADQRFPLSSTFKTLACATLLQRVD +AGSEQLTTSVSVSSSDLVTYSPVLEEYADTRITLFELCEATMTTSDNTAANLILQRLGGP +ESVTDFARQLGDSVTRLDRWETDLNQAIPGDERDTTTPNAMVSNLEQLLSDKVLSLESKQ +YLQTWLVNNKVADGLFRSSMPGDWVIGDRTGAGGFGSRSITAVIWPAEREPVFVAFYITE +TTASFEERNAAIAQLGRVLI--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia jejuensis TaxID=328049 RepID=UPI00082FCA5F +---AEARLRQLEQEHDARLGVFAVDTGTGKTL-AYRGDERVGIGSTFKGVACAALLREHP +LSTGYFDQVVHFTKADLVANSPISETRVDAGMNVLELCNAAITVSDNTAGNQLLKLLGGP +EALTAFFRSIGDQVSRLDRWEPDLNANVPGDERDTTTAAALAADYRAFVVGDLLAAPEKG +QITSWLLANTTGGARIRAGLPADWKTADKTGTGDYGVANDIAITWPADGAPVVIGVLSTK +STKDAQADNPLVAAAAKVAVD-- +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A649UIS5_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIV------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces kaniharaensis TaxID=212423 RepID=UPI001295CD6B +----TASFNELEQRFGARLGVYALDTGSGREI-VHRADERFAFASTSKALATGALLRHAS +--DEQLDKVVAFRTEDLLKWAPITSQHVATGMRVRDLASAAIEYSDNTAANLVTAELGGP +AAIQQALRDLGDATTNVNRTEPTLNEATPGDPRDTSTPRVLAADLRRYVLGDVLADDRRR +LLTDWLVANTTGGPYIRAGLPADWKVGDKTGNAGYGTRNDIAVVWPSGGSPLVIVVLSDR +GKPDATSDDALIAQATRAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium paragordonae TaxID=1389713 RepID=UPI00105B8F26 +--DLTSRFTEIERRYQGRLGVYVPASGAIPAI-AYRADERFALCSTFKAPLVAAVLHQYP +--LSYLDQRVTFSKADISSPSPIAEQHIDTGMTVGEMCDAAIRYSDNTAANLLLNRIGGP +AGFTAYLRSLGDSTSRLDHAEPELNRDPPGDERDTTTPHAIAVTMQQLVLGDALPQDKRA +MLTDWMARNTTGGKRIRAAFPADWKVSDKTGSGDYGRANDVAVVWSPAGVPHVVAIYTDI +AGYDAQPNDTFVADAARIVAS-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. JB150 TaxID=2714844 RepID=UPI0014099286 +----TGRLRDLERHYGAKLGVYARNLRTGRTV-RHHADDLFPICSVFKTLAAAAVLRDLD +RDGEFLARRIHYTEADLVDGSDKTREHLAEGMTVAELCDVTIRFSDNAAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYARLVLGDALPGADRE +LLTHWLLHNTTSGDRLRAGVPPTWTVADKTGGGAYGTNNNVGIAWTPDGTPVVLAVLSRK +FDPAAVRDNALIAQTAAVL---- +>[subseq from] Beta-lactamase n=1 Tax=Bordetella genomosp. 7 TaxID=1416805 RepID=A0A261RJD8_9BORD +--TVAETAARVEARLGGRVGVALQRLGEPAVA-LYRADERFPMASTFKALACGALLAKVD +AAEQSLDTVVLYGPETLVPYSPVTAQHVGKGMTLAQLCHATITLSDNTAGNLVLRRIGGP +AGLTAFLRSTGDEMSRLDRWEPELNEALPADPRDTTTPRAAAGTLGRLLFQGVLSPGSSH +QLEAWMIADQVADELIRASLPQGWGIGDKTGSGERGSRSIIAVIRPPHGKPWLASIYLTG +SSSRPQERNAAVAEIGRSMI--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000C152992 +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTSANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGTPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Sge12 TaxID=1972846 RepID=A0A1V0QUX0_9ACTN +---VVARLRELEREYGARLGVYARDTATGRTV-AHRADELFPMCSVFKTLAVAAVLRDLD +HDGAHLAKRIHYTLQDVTDGGSVTERNIAGGLTVAQLCSAAIAQSDNLAGNLLLRELGGP +TAVTRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLALGDALDSGDRE +QLNRWLLSNTTSADRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPLVLSILSTL +PEPTAPRDNTLIARTAKLLAD-- +>[subseq from] Clavulanic-acid inhibited carbapenemase IMI-2 n=12 Tax=Enterobacteriaceae TaxID=543 RepID=G9HXF8_ECOLX +-----DEIKNLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ +DNQLNLNQIVNYNTRSLEFYSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +NEKEAKHEDKVIAEASRIAID-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBP8_STEMA +----ATDFAALEKACAGRLGVTVLDTASGRRI-GHRQDERFPLCSTFKTVLAATVLDQSR +RVPGLLDRRVPVREADLLSHAPVARRHAGKDLTVRDLCRATIITSDNTAANLLFDVVGGP +PAVTAFLRAQGDSVTRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRLVLGDALAPGARQ +QLADWLIDNETGDACLRAGLGARWRVGDKTGSNGEDARNDTAVLWPMGGAPWVITAYLQA +ADIRNDQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium bourgelatii TaxID=1273442 RepID=UPI0013D33463 +-qDLSARFAELERRYESRLGVHVLADGDAAPI-SYRADERFAFCSTFKAPLAAAVLQRNP +--LTFLDKVITYTRDDIRSTSPITEQHVDGGMTIGQLCDAAVRYSDGTAANLLLAEIGGP +AGFTQFLRSLGDSVSRLDQLEPELNRDAPNDERDTTTPRAIAGVFQRLVLGDALPADKRG +LLTDWMVRNTTGDKRIRTGFPPDWKIADKTGSGDYGRTNDVAVVWSPSGASYVVAIYSDC +VTYDAPFNDAIVAAAATIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Moraxella sp. RCAD0137 TaxID=1775913 RepID=A0A2K0XQC1_9GAMM +--TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP +--EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNTATNLLLKELGGV +EQYQRILRQLGDNVTHANRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT +ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ +FTEEAKFNNKLVEDAAKQVFH-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. adm13(2018) TaxID=2479007 RepID=A0A652L7B1_9ACTN +---LLARLRALEERHAARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTFAVAAVLRDLD +RDGSFLARRLRYTADDVTRWSPVTERNIAHGMTVSELCDATLRFSDNTAANLLLRELGGP +TSVTRFARSIGDRTTRLDRWEPELNSAEPWRETDTSTPRAVGRSYGRLLLGAALPRDDRE +RLTTWMLANTTSTERFRKGLPADWLLADKTGGGRYGGNNDAGVAWKPDGGPVVLTVLSTR +FTEDAAPVDALVADAAALVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 3212.4 TaxID=2135786 RepID=A0A495H540_9ACTN +-----TELRDLERRYGARLGVYARNARTGRTV-AYRAGERFAMCSTFKAFAAAAVLRDHG +-DCAPLDRVVHYPPRDILANSPKTEEHLSTGMPVGDLCAAAIQYSDNAAGNLLLRQIGGP +DGLTRFFRSLGDGVSRLDRWEPDLNTAVPGDPRDTTTAEALGRGFERLTLGRALDEAGRA +LLVAWLKGNTTSARRFRAGLPQGWVIGDKTGTGDYATAHDLGVAWTTRNTPILLTVLSAK +AAKDAPMDEALIAEAARVLA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Xanthomonadaceae bacterium NML93-0399 TaxID=2032565 RepID=A0A2A3LNG3_9GAMM +------VFAALERAAGGRLGVALLDTGTGRRV-GWRDEARFPMCSSFKWLLAAAVLHAVD +RGAIGLRQAVAVHADDIIAHSPYVQTRVDGGATVSDLCRATVIESDNAAANLLLPLIGGP +AGLTAFLRGNGDPVTRLDRNEPTLNEAAAGDPRDTTSPRAMVDDLHRLLLGDSLRAPSRA +MLTAWLVDNRTGDARIRAGVPAGWIVGDKTGTCGAGTAADVAVLYPPDRAPLLLAVYVHG +ASISGPAMDALHADVARAVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI0009DFE4D4 +----RADFERLERAFGARLGVYAVDTATGREV-AYRADERFAYASTHKVFTAGGVLQRTP +--VAELDRTVTYSPQDVVTGSPVTEKHVGTGMPLRAVMDATLRYSDNTGGNLLFRELGGP +AGLTAVLRGIGDTTTHVDRIETELNDTAPGDIRDTSTPRALAVGLRAFALGDALPEDKRK +ILVDIMRGNTTGDANIRAGVP-GWPVADKTGTASYGTRNDIAVVWPPNRAPIVLSVLTDR +SAKDAKIDNALLAQATVATV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 3211 TaxID=1964449 RepID=UPI0009A4ACA1 +---VVARLRELEREYGARLGVYARDTATGRTV-VHRADELFPMCSVFKTLAVAAVLRDLD +HGGAHLAKRIHYTLQDVTDGGSVTERNIAGGLTVAQLCSAAIAQSDNLAGNLLLRELGGP +TAVTRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLALGDALDSGDRE +QLNRWLLSNTTSADRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPVVLSILSTL +PEPTAPRDNTLIARTAKLLAD-- +>[subseq from] Beta-lactamase IMI-3 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=D0V475_ENTCL +-----DEIKNLETDFNGRVGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ +DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILSEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +NEKEAKHEDKVIAEASRIAID-- +>[subseq from] Beta-lactamase IMI-3 n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A0M3STF3_RAOOR +-----DEIKNLETDFNGRVGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ +DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILSEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +NEKEAKHEDKVIAEASRIAID-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase IMI-17 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A2D3E5L4_ENTCL +-----DEIKNLETDFNGRVGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ +DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILSEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +NEKEAKHEDKVIAEASRIAID-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=UPI001261608F +----AKDFAALEVASGGRLGVTLLNTGTGWRT-GNRQDERFPMCSTFKFVLSAAVLHLAD +QGRLSLDRRVAVRQQDMLSHAPVTTRHIGKDVTVRDLCRATMITSDNPAANLLLGMVGGP +AGVTAFLRANGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRFVLGDVLKPASKQ +QLADWLIDNETGDTRLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ATVDDAGRNDVLRQVAVI----- +>[subseq from] class A beta-lactamase n=1 Tax=Asticcacaulis biprosthecium TaxID=76891 RepID=UPI00068276C9 +-----TAMLDITKRHGGRIGVSAIDAGSGARL-SVSAQDRFGMMSVFKWILAAAVLARVD +KGELKLDQVVRYSAKDLIAYSPVTEKEVKDGMAVGELCAATVSKSDNTAANLLLPLVGGP +EGLTKWIRSLGDAVTRCDRKEPELNVVAEGDPRDTTTPEAMTQLLQIVFSGAALEADSIK +QLRDWMEATSTGDKRIRAGVPSGWTVGNKTGTAN-GAVNDVAVIWPKSEGPIFLSIFTTG +GALEADAKEQVVADIARLVCEVf +>[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000BA24DCF +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKA---------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. RV15 TaxID=909626 RepID=A0A101V4G5_9ACTN +----AARLRELEAQHSARLGVFAYNAATRRTV-RHRADELFPMCSVFKTLASAVVLRDLD +RHGEFLSHRIHYTEADLPEGSDQTRKHLADGMTVAELCEVAITYSDNGAANLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRITDTTSPYAIARTYGRLVLGDALPRHDRD +LLTHWLLNNTTSGRRFRAGLPTSWTLADKTGSGSYGTANDVGVTWTDTGTPLVLAVLSTR +PDQDAAWDDALVAETAAVLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacterium sp. XM4083 TaxID=2583238 RepID=A0A505H6N4_9MICO +--AADSAFTQLEDDFDARVGVYAVDLDTGREI-AWRADERFAYASTIKAMASAALLDEVG +--TDGLSKDIAVDEDDLVSHSPVTETNVGGTMTLAELCEAAMTQSDNGAANLIVAELGGP +ASLDSRLDDLGDTGTTVSRIEPGLNEATPGDPRDTTTPRASASNLRKYVFGGVLSDDEAT +TLTDWMKATQTGDTLIRADLPEEWTVGDKSGTGSYGSRNDLGIIWPDDGGPIVISVLSSK +KEKDAEADDRLIARAAASAVD-- +>[subseq from] Class A beta-lactamase n=4 Tax=Streptomyces TaxID=1883 RepID=A0A5P2BGQ1_STRVZ +--RLAPRFDAIERKHGGRLGVYALATGTGATL-AHRADDRFAFCSTFKALAAAAVLDRHP +--LRHLDKRVTYTAADVDSISPVTEKRIATGMTVGELCDAAIRYSDGTAGNLLMRQIGGP +AGLTAYLRGLGDEVSRMDDYEPELNDVPPKDPRDTTTPRAVAADYRALVLGDALPAAKRA +LLAGWLGRNATGARRIRAGVPKGWRVADKTGTGDWGRANDIAVLRPPDADPLVLAVMTDR +PGRDTPPVDAFIAEAAELVVA-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1IJX5_9ZZZZ +----------------------------------------FPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Lentibacillus jeotgali TaxID=558169 RepID=UPI00026267CD +-----EKFVQLENEFDAQISVYAMDTGTKQTI-EYRPNERFAYSSTFKPLAAAILLKQNN +--IENLEKVVTYTNDDLVTYSPVTEKHVDAGLTLLEISEAAIRKSDNTAGNLLLEAIGGP +DKFEHALRDIGDDVTQPERYETELNEFTPGNKRDTSTPRAMATNLKKVALGDFLPGDKRE +LLIDWMTGNESGDPLIRAGAPEKWTVVDKSGAGTYGTRNDIAVVWPPNKEPIVIAIMSRH +DTENAEYDDALIAKAAEITLNAf +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase IMI-15 n=1 Tax=Enterobacter cloacae subsp. cloacae TaxID=336306 RepID=A0A1S6QNP3_ENTCL +-----DEIKDLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ +DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +TKKEAKHEDKVIAEASRIAID-- +>[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0009BF9EA8 +--TFQQALAKLEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVQEYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRGLGDTVTRHDRYEPELNRPHPSEPQDTTTPRAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. 1.19 TaxID=1925589 RepID=UPI000948C5CD +----QQVAQQVEAQLPGRVGYAELDLASGQLLsGWRAQARFPLNSTFKVLLCAAVLARVD +AGQEQLARRIRYLPGDLVAWSPVTERHLADGMRVDALCHAAITVSDNTAANLLLNTLGGP +SALTAFLRRIGDTETRLDRWEPALNSAEPGDVRDTTTPERLARTLRRLIDGNTLSAASRQ +QLLAWMEADSVGGPLLRSVLPPGWYIADKTGAGEHGSRGIVALLGPGGTPTRIVVIFLTD +NPASLDVRNQHIARLGASLIAHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. NRRL WC-3618 TaxID=1519490 RepID=A0A0N0T8Z5_9ACTN +--EVTARLHTLETQHGARVGVFAHNLATKQTI-RHRADERFPICSLFKTLAAAAVLRDLD +RSGEVLSKRVHYTADDLVDGSKQTEEHLAEGMTVAELADVAIRFSDNTAGNLLLRELGGP +TAITRFARSVGDRATRLDRWETELNSAEPWRRTDTTTPYAIGRTYARLVLGDVLNRPDRE +LLTHWLLTNTTSGNRFRLALPPTWTIADKTGAGSYGTNNNVGVAWTQDGTPLVLAVQTTK +PDQDAAADHPLVAETAAVLAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. URHA0013 TaxID=1380352 RepID=UPI00047F83EF +--DAQPELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEDQLAAMIPYGKADLLEYAPVARQNIAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLLTGEALSATSRA +QLTEWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDVAVAWPKPDAPILIAAYTQG +GTPTAAQIETVFARIGRIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=A0A3N1KGQ2_9GAMM +----AKDFAALEVASGGRLGVTLLNTGTGWRT-GNRQDERFPMCSTFKFVLSAAVLHLAD +QGRLSLDQRVAVRQQDMLSHAPVTTRHIGKDVTVRDLCRATMITSDNPAANLLLGVVGGP +AGVTAFLRANGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRFVLGDVLKPASKQ +QLADWLIDNETGDTRLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ATVDDAGRNDVLRQVAV------ +>[subseq from] Beta-lactamase n=1 Tax=Umezawaea tangerina TaxID=84725 RepID=A0A2T0TGX3_9PSEU +--TATADLTALEAGLGGRIGVHAVDTGTGTTV-AHRADERFLMCSTHKALVAAAVLRTGV +----DLDRLVRYDESELLSYAPVTSQHVADGMTVAALCEAAITRSDNTADNLLLEILGGP +QAVTAFVRTLGDDVTRLDRVEPDLNVGAPGDERDTSTPARMVADLRELVLDDGLDPAGRD +RLTGWLTANTTGDDLIRAGLPAGWRVGDKTGSGAAGEVNDIAVVWPPGRAPWVVAVYAVP +TDPKSTAVRAAVASASRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Kribbella flavida TaxID=182640 RepID=UPI00059E88F5 +-------FGKLEKKYGARLGVYAVDTGSGREI-AHRADERFAYASTFKALAAGAVLRKYT +--LQGMGKVVKYSESDLLANSPITEKHVATGMTLRELCDAAVRYSDNTASNLLFDALGGP +KGLDAVLAELGDNVTQMEQRELELSVWDPSNPRDTSTPRAFARNLRTFVLGDALRAPERA +QLTTWLRTNLTGAELIRAGMPKGWVVGDKTGTATYGGRNDIAVVWPPGRAPIVLAIFSNR +PAAEAEHDNRLLAEAARVVAAAy +>[subseq from] Class A beta-lactamase n=3 Tax=Rhizobium meliloti TaxID=382 RepID=A0A6A7ZSQ1_RHIML +-hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSRFKALASAMVLARVD +KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP +PALTEFVRSFGDELTRLERFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA +QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDIAVAWSPNRGAIVVATYCEI +PTISADERNAVVAEVGRLVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces odonnellii TaxID=1417980 RepID=UPI0006269039 +----HDRLIELERKFEARLGVYALATGTGEGI-AHRADERFAFCSTFKGVAAAAVLHHNP +--LSHLDTVVRYTDDDLMKHAPITSQNVAKGMTIRQLCDAAVRYSDGTAGNLLLRDIGGP +AGLTAYTRTLGDTVTRINRTEPAISEAVPGDPRDTTSPRAFGTNYQKFVLGNALPGEKRA +FLRDLLERNTTGAERIRAGVPRGWTVADKTGTGSYGTLNDMAIVWPPKSPPLVIAVMSTK +AGKDAEYDQSLIAEAAAYAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces varsoviensis TaxID=67373 RepID=A0A0L8QEL8_9ACTN +-----HTLKGLEGKYDAKLGVYAVDTGSGREV-TYNDGERFAYNSTFKALAAGALLRKYS +--LSGMDRLITYSKDDLIADSPVSEKHVDSGMKLGELCDAAIRFSDNTAANLMFDELGGP +KALNAELKKIGDDVIRMERREPQLSRWVPGETRDTSTPRAMAADLRAFVLGDVLHKEERA +QLTTWLRTNKTGDELIRAGTPKSWVVGDKTGTGSYGARNDIAVLWPPHKAPIVVAILSHR +NKKDAKFDNKLIAETAKVVT--- +>[subseq from] Class A beta-lactamase n=1 Tax=Aquabacterium sp. TaxID=1872578 RepID=A0A5C8BCH3_9BURK +--QMTAALQQLEAKAQGRLGVHVIDTANGHEF-GYRSDETFMMLSSFKLLASALVLARVD +RGQESLERRIRYRKQDLVPWSPVTEAYADGELTLAQLCHATITTSDNTAGNLILASYGGP +KALTQFARKVGDKVTRLDRIEPDLNIRVEGATLDTTSPRAMAMTMNKLLVGDALSPTSRK +LLRQWLLENTTGGKRLQAGVPADWTVGDKTGTNKT-DANDIGILLPPQGAPVFVTAYLSD +SPATSQIKEETLAKVGRLAA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0008F4D052 +-----GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGTVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004C5BDD0 +----VRRLRALEREYGARVGAYARDTGTGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD +RDGEFLARRIHYTQGDVTAGGSVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP +TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE +LLTRWLVSNTTSDDRFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK +PDAAAPRENALVARAAEVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia jiangxiensis TaxID=282685 RepID=UPI000303516E +--ALSGRFGELEGRFGARLGVFALDTGSGHIV-EYRADERFAFCSTFKALEAGAILTTAG +--PAELDRRITYTATDLTAYAPITRPHVTDGMTVRDLLDAAVRYSDNTAANLLFGLLGGP +AGLQHDLRNLGDQVTRSDRLEPALSEATPGDPRDTSTPRTFATDLRTYVLGTALPTDNRT +LLTTMLRTNTTGAGLIRAGVPADWVVGDKTGNGDYGTRNDIAVLWPPHRAPIVLAVMSTR +HGHDDTYDNALIAQAANAAVT-- +>[subseq from] BCL family class A beta-lactamase n=1 Tax=Bacillus clausii TaxID=79880 RepID=UPI000BA5B00A +-----AVFKALEEEYAARLGVFALDTGTGQTV-SYRADERFTYASAHKPLAVGVLLQQKS +--IEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANLIFDEIGGP +EGFKEGLRAMGDTVTEPERIEPELNNVEPGEIQDTSTPEALAKSLQEFTLGEALPADKQE +LLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILWPPEKEPIILAVLSSK +DEKDAEYDDELIAKATEEVI--- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase IMI-16 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A218MJA7_ENTCL +------DIKNLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKRSQ +DNQLSLNQIVNYNTRTLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTIALGNILSEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +YEKEAKHEDKVIAEASRIAID-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. WAC05950 TaxID=2487419 RepID=A0A3R9WN53_9ACTN +----VRRLRALEREYGARVGAYARDTGTGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD +RDGEFLARRIHYTQGDVTTGGSVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP +TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE +LLTRWLVSNTTSDERFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK +PDAAAPRENALVARAAEVLA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=[Pseudomonas] geniculata TaxID=86188 RepID=UPI00070C0BA3 +-----GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGTVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] BCL family class A beta-lactamase n=1 Tax=Bacillus clausii TaxID=79880 RepID=UPI000BA4F40B +-----AVFKALEEEYAARLGVFALDTGTGQTV-SYRADERFTYASAHKPLAVGVLLQQKS +--IEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANLIFDEIGGP +EGFKEGLRAIGDTVTEPERIEPELNNVEPGEIQDTSTPEALAKSLQEFTLGEALPADKQE +LLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILWPPEKEPIILAVLSSK +DEKDAEYDDELIAKATEEVI--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia hydrocarbonoxydans TaxID=76726 RepID=A0A4Y3WNF1_9PSEU +------DLAALEGRFGGRIGVHALDTGTGATV-THRGGERFLMASTAKLPLAAAVLDRAV +TDPALLDRLVRYGPGALLEYAPVTTANVATGMTVADLCDAALTVSDNTAANLLLDLLGGP +AAVTAFVRGLGDPTSRFDRTEPDLNSTGPRDERDTTTPAAIVATVRAVSLGDALPPAARD +RLTTWLVANTTGDTAIRAGVPGGWVVGDKTGTGAQGERNDIGIVRPPDRAPLVLAVYTDP +DVADATAGDATVAEATAIAVR-- +>[subseq from] Class A beta-lactamase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=A0A2M9H4U4_9BURK +--TFQQALAKLEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVQEYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRGLGDTVTRHDRYEPELNRPHPSEPQDTTTPRAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWRIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces sp. SID8385 TaxID=2690364 RepID=UPI001361818B +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELSEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Shinella sp. 65-6 TaxID=1895831 RepID=A0A1M3CAB0_9RHIZ +-eALEGRLAELEGRHKGRIGVAIHNLATGARL-GHRADERFLMCSTFKALLAGYVLARVD +RKEEALDRRIVVKKADLLDWSPVVEKHVGKAISVARLCEATITLSDSAAANLLLAGSGGP +EAVTRFLRGLGDAVTRLDRTEPALNYETADDERDTTTPIAMAETLRRLVFSDVLSPSSRA +QLAAWLVMNKTGDTRLRAGFPAGWITGDKTGTNGHGNANDVAVAWSPDRGAIVVTAFCEI +PGISGDARNAVIAEIGRIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=A0A193BYN4_AMYOR +-----AGFERLERAFGARLGVYAVDTATGREV-AYRADERFAYASTHKVFTAGGVLQRTP +--VAELDRTVTYSRQDVVANSPITEKHVGTGMPLRAVMDATLRYSDNTGGNLLFRELGGP +AGLTAVLRGIGDTTTHVDRIETELNDTAPGDIRDTSTPRALAVSLRAFALGDALPEDKRK +ILVDIMRGNTTGDANIRAGVP-GWAVADKTGTASYGTRNDIAVVWPPNRAPIVLSVLTDR +STKDAQIDNALLAQATVATV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. YIM 121038 TaxID=2136401 RepID=A0A5B7ULA7_9ACTN +---YARAFKKLERKFDARLGVYAVDTGTGREV-AYHDGRRFAYNSTFKALAAGETLRSYA +--PDKMDQVVKYSKDDLVTYSPITEKHVDTGMTLRALCDAAVRYSDNTAANLLFDKLGGP +KGLDAALERIGDDVTRMERVEPLLSRWVPGEKRDTSTARALAKDLRAYVLGDVLAGPERA +QLATWLKTNTTGDHVIKAGVPKNWVVGDKTGTGSYGARNDIAVVWRPDAAPLVVAILSHR +GDKDAAPDDKLIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Sciscionella sp. SE31 TaxID=1445613 RepID=UPI0004DED5A2 +--EASTRFSSLERKYDARLGVYALATGTGASL-GYREDERFAFCSTFKTLAAAAVLQRNP +--LSHLNKVITYDKNEVNSISPITERHIGTGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP +GQLTHYLRGLGDTASRMDQYEPELNRDPPGDPRDTTTPRSIAHDYRKIVLDDALPPEKRA +LIKDWLQRNTTGAQSIRAGVPHGWGVADKTGHGDYGRANDIAIVTPPGRNPLVIAILSDR +AGYTAEARYPIIAEAAKYVV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces bauhiniae TaxID=2340725 RepID=A0A4Z1D9F1_9ACTN +---LRPELAALEKRYGARLGVYAHNTRTGATV-AYRADESFAMCSTFKAIAAAAVLRDHG +-GRAALGEVIHYPPADILANSEQTKAHQETGMALGEVCAAAIQYSDNTAGNLMLRRIGGP +AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPRALGRTFELLTLGRALSGGDRE +QLVGWLRGNTTSGKRFGAGLPSDWVLADKTGTGSYATANDLGVAWTGKGTPLLLSVLSTK +PTPDAPVDEALIEETARLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. 3058 TaxID=2561921 RepID=A0A4Z1CTJ6_9RHOB +--TVTEAARAIEADLGGRIGVSLRQPGGAGAT-GYREDERFPLSSTFKAPLCGAILTLVD +AGEDQLDRRIGYSSGDLVTYSPVTEAR--DAMTVVELCEATITLSDNTAANLLLDRLGGP +EDFTEYLRAIGDDTTRLDRWETDLNAAVPGDPRDTSTPAAMTATLETLLFGPVLSDAAQQ +QLEAWMRANQVADDLIRASLPEGWIIGDKTGAGGYGSRSIVAVIRTPQGDPWLASVYLTG +SEADMPTRNRAIARVGAAIVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Prauserella marina TaxID=530584 RepID=UPI000B8099A3 +----HDRLHELERDYGARLGVYALATGSGAVV-EHRADERFAFCSTFKGLAAAAVLQRNP +--SSHVDTVLTFTEADLLSSSFVTREHVASGMTIGQLCDAAVRYSDGTAGNLLVRDLGGP +GEFTAFLREIGDEVTRMDRPEPELTEAKPGDPRDTTSPRAIGTDYQGIVLGDVLPEDKRG +FLRDLLERNTTGDERIRAGVPEGWTVADKTGTGSYGTMNDIGIGWPPSGEPLVIAIMSSK +ADPDSDYDQKLIADATEYVVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus kimchii TaxID=746691 RepID=UPI00034BDC71 +----SEAFKKLEDEFDVKLGVYAIDTGSNKEI-NYQENDRFAYASTFKPLAVGAILQTKS +--DPELQEVIRYTEEDLVTYSPITEKHVDEGMTLLEISDAAIRYSDNTAANLLLEAIGGP +DELETKLRDIGDEIIEVDRYETELNEATPGDIRDTSTPKAMANSLQQYVLEDVLDADRRE +ILTNMLINNTTGDALIRAGVPEGWTVGDKTGAGGYGTRNDIGIIWPEDNEPIVIAIMSSR +DVEDADYDDKLIEKATKVVVKE- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase IMI-12 n=2 Tax=Enterobacter cloacae complex TaxID=354276 RepID=A0A173GTS2_ENTAS +-----DEIKNLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ +DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +NEKEAKHDDKVIAEASRIAID-- +>[subseq from] Class A beta-lactamase n=1 Tax=Azonexus hydrophilus TaxID=418702 RepID=A0A1R1I8N1_9RHOO +--HLRSRWRELEQQGGGRLGVHLLDTATGAEY-GYRQDERFMLLSSFKQLASALVLQRVD +TGREALDRRIVYDRSVLLPWSPVTEQHADGQMTLAALCEAAITTSDNAAANLILASYGGP +AALTAWLRQLGDGVTRLDRNEPELNTKHSQGELDTTSPRAMTQTMQKLLLGDVLSPASRT +ILQRWLLANTTGGRRLKAGLPTDWRIGDKTGTNRS-DANDVGIVWPAGGKPLLVSAYLAD +STAAPAAREACLAGVGRLLVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. NAS80.1 TaxID=1680159 RepID=A0A1Q5R357_9BRAD +------ELASYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLASMIPYGQADLLSHAPAAKQNLATGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPQDTTTPAAMAGNLRRLVLGESLSPASRT +QLTDWMVNCKTGANRLRGGLPISWKIGDKTGNNGKDASGDIAVAWPKNKTPILIAAYTQG +GTPNAAQIEAVFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia (strain R551-3) TaxID=391008 RepID=B4ST44_STRM5 +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDALSRSDRLEPELNSFAKDDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIGVLWPVGGAPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Franconibacter helveticus TaxID=357240 RepID=UPI000405F8A6 +--ALTAAAQQEEKTLNARIGVTVLDTVTGKTL-SYRGDERFPLNSTHKPLLCGALLKQAQ +EKKIRLTDSVLFDKSQLVDYSPVTEKHVSPQMNWLQLCSAAVSYSDNTAANLISQKAGGP +QAITAFVRASGDNITRLDRFEPELNEARPGDERDTTTPDAISHTLQKLLLGDVLSEASRQ +QLTRWMAEDKVADALLRKSLPKGWKIADKTGAGGYGSRSIISMVWPEKGAPMVVAIYITL +TEASLAQSNDAIARLGGVIF--- +>[subseq from] Beta-lactamase n=1 Tax=Prauserella marina TaxID=530584 RepID=A0A222VNQ1_9PSEU +----HDRLHELERDYGARLGVYALATGSGAVV-EHRADERFAFCSTFKGLAAAAVLQRNP +--SSHVDTVLTFTEADLLSSSFVTREHVASGMTIGQLCDAAVRYSDGTAGNLLVRDLGGP +GEFTAFLREIGDEVTRMDRPEPELTEAKPGDPRDTTSPRAIGTDYQGIVLGDVLPEDKRG +FLRDLLERNTTGDERIRAGVPEGWTVADKTGTGSYGTMNDIGIGWPPSGEPLVIAIMSSK +ADPDSDYDQKLIADATEYVVT-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0006AED99F +----VRRLRALEREYGARVGAYARDTGTGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD +RDGEFLARRIHYTQGDVTAGGSVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP +TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE +LLTRWLVSNTTSDERFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK +PDAAAPRENALVARAAEVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces spongiae TaxID=565072 RepID=A0A5N8XNI1_9ACTN +----NGELKELERKFDARLGVYAIDTGTGREV-AYRDGERFGYHSTHKALSAGAVLRKYG +--LNGMNEVIKYSEDDLVHHSPVTEKHVETGMTLSELCDAAVRFSDNTAANLLFDALGGP +KGLQAELRKLGDKVTLMERVEPGLSDWVPGETRDTTTPRALAKDLRAYVLGDVLRGPERD +RLTTWLKTNTTGDEVIRAGVPDGWVVGDKTGSGGYGARNDIAVVWPPDSAPIVMAILTNR +GEADDTYDNKLIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CG 926 TaxID=1882405 RepID=A0A2V2B2V8_9ACTN +-------LRALEREYGARLGVYALDTATGRTV-VHRADELFPMCSVFKTLAAAAVLRDLD +HDGAHLAKRIHYTPQDVTDGGSITEKNIANGLTVAELCSAAIAQSDNTAGNLLLRELDGP +TAITRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLTIGDALDSGDRE +RLNRWLLSNTTSGDRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPMVLAILSTM +PEATAPRDNTLIARTAKLLAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDFEA7B +----EERLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD +KGEEKLDRRIRYSEGDIIGGSPATKLRVGDGMTVAELCAAAVALSDNAAANLLLASFGGP +KALTAFCRSLGDDLTRFDRTEPTLNYDTPDDQRDTTTAAAMLENLRRLLFTDVLTAASRS +QLAAWLITNKTGDARLRAGVPKDWLVGDKTGTNGAGNANDIAVLWPSKRAPIIVTAYCEI +PSISADERNAVIAEIGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_039 TaxID=2175624 RepID=A0A2W1TYK6_9MICO +--ATARAFAALERRYDARLGVVAVDTGDGRTI-EHRAGERFAFASTNKVFIAAAVLDASS +--DADLATVVHCDRGDLLEYAPVTSGYVDTGMTVRELIDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTRVDRVEPDLNEATPGDPRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAIVTPPGRAPIVLVVMTSR +ADPGAEPSDALVAAATRAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Oleiagrimonas citrea TaxID=1665687 RepID=UPI001445A51D +---IHTRLAALEKRHGGRLGVAMLDTASGRQI-GYRADHRFLMCSTHKVLVVAALLARVD +RGIEDLQRRVIFDHQALLDYAPVTRRHVGAPMTLEALCEAAITLSDNTADNLLLNALGGP +DAVTAYARSLGDRVTLLTRTEPALNLALPDDPSDTTTPQAMLSDLRDLLIGEALHPASRQ +RLLGWMRACQTGSRLLRAGLPRAWRCADKTGRGAANEIHDIGLIEPPHGKPVLVCAYYAD +SIAPEAARESVLADVGRLAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea septica TaxID=472695 RepID=UPI000534DBE9 +-------AQQEEQALKARIGIAVIDTGAESVA-SYRGDERFPLNSTHKALLCGALLSAQD +KGKLRLTERTQFDRTALVTYSPVTEKFVAPAMSWQQLCSAAISYSDNAAANLIAKKLGGP +IAVTRFFADLGDKVTRLDRSEPELNSAIPGDVRDTTTPLAVSETLRQLTLGEALTPASRA +QLLQWMRDDKVADALLRSVLPTGWSIADKTGAGEYGSRSIISVVWPQNGKPLIIAIYITQ +TEATLAQSNAAIARIGKAIF--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces chilikensis TaxID=1194079 RepID=UPI0014093079 +-----PRFRALEREFDARLGVYALDTGTGRSV-GHRADDRFAYASTFKALAAGAILRKYG +--TDGIDKVVTYSRNDVVANSPVSENFVGTGMSLRGLCAATLRYSDNTAVNLLLDELGGP +DGLEEVLEEFGDDVTEMDRYEPEMSDGTPGDIRDTSTPRAMAESLRAFLLGDALERDERE +LLRQWMTTNMTGRTLIRAGVPDGWDVADKSGSAGYGGRNDIAVVWPEDGDPIVMAVMSTR +GKQGADRRDALIAKAATVAAD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. H036 TaxID=1519487 RepID=A0A0M8UDN8_9ACTN +----VRRLRALEREYGARVGAYARDTGTGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD +RDGEFLARRIHYTQGDVTTGGSVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP +TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE +LLTRWLVSNTTSDERFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK +PDAAAPRENALVARAAEVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sedi TaxID=555059 RepID=A0A5C4UU38_9ACTN +--EAAEEFEALEDEFDARLGVYALDTGSGGEI-AHRDDERFAYASTFKALLVGAVLDAHG +--TDGIEEVVDYTEDELVDYSPVTENFVDSGMSLSQLSAATLWYSDNTAANLLLDAVGGP +DGLQEALREMGDDTTEVSRYEPELNEATPGDTRDTSTPRAMADDLRALLLEDALGERERH +LLRQWMETNTTGGTLVEAGLPAEWTVADKSGSAGYGGRNDIAVVWPDDGDPIVLAVLSSR +DEEDAERDDALVARAATVAV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces viridochromogenes (strain DSM 40736 / JCM 4977 / BCRC 1201 / Tue 494) TaxID=591159 RepID=D9XGI8_STRVT +-----------------GLGVYARNLRTGRTV-TYRAAERFPMASVFKTLAVAAVLRDLD +RDGEFLARRIHYTQDYVTEFSPVTEDHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP +TAVTRFCRSVGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGDVLEPRDRA +RLTDWLLRNTTSIDRFRKGLPADWLLADKTGGGQYGSNNDVGITWPPDGPPIVMSVLTTQ +PEEDAPADNPLVAETAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia arthritidis TaxID=228602 RepID=UPI001428685B +-----GEFDALETEFDAHLGVFGIDTGSGRTV-EHRADERFAYASTSKALLAGVILATTA +--PADLELRIKYTSADLVANSPISEQHLADGITLREVLDAALRYSDNTAANHMFARLGGP +KGVERNLRALGDNVTQMDRTETALNEAIPGDTRDTSTPRALAADLRKYLLDSALTPEARA +ILTDMMRRNTTGGELIRAGVPADWQVADKTGSAAYGTRNDIAVLWPPNRAPIVLTVLSTR +AKQDASYDNALLAKAAKIAVQE- +>[subseq from] class A beta-lactamase n=1 Tax=Clostridium sporogenes TaxID=1509 RepID=UPI0005ED6A56 +---YNSAFSQLESDYDVKLGIYAFDTEMNKEV-AYHADDRFAYCSTFKALAAGAVLKQDS +--LDELKQVVKYKKEDVLSYAPIAKDNVDKGMTIEEICNAAVRFSDNTAANLLFDHIGGP +SGFKSALNQLGDNVTQPARIEPELNEAIPGDIRDTSTPRQLATDLQAYTTGNILTDDKKK +ILIDWMTGNATGNTLIRAGAPDNWVVADKSGTGPYGMRNDIAIVMPPNKKPIIIAILSTH +HTKEAKYDDKLIAQASKIVFDFf +>[subseq from] Beta-lactamase n=1 Tax=Murinocardiopsis flavida TaxID=645275 RepID=A0A2P8CF33_9ACTN +---ADREFKELEGEFDARLGVYAIDTGSDRTL-SYQEDERFAYCSTHKSLSVGAVLEQNS +--LKEMEKLITYTEEDLVAYSPITEKHVDEGMTLRAVSDAAVRYSDNTAANLLFEELGGT +NGFGDALKGIGDDVTDVSRIEPDLSEGTPGDVRDTSTPQQMATDLREYTLGDTLSTKKRA +ILTDLLVRNTTGDELIRAGVPDGWKVGDKTGSGGYGTRNDIAVIWPPEDDPIVLAIMSSR +DTKDAESDDKLIAESAEVAID-- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudonocardia thermophila TaxID=1848 RepID=A0A1M6P9Y8_PSETH +------------ARRGVRLGVHAVATADGREL-AHRADERFAHCSIVKVLAAGAVLDRFP +--IEQLDRRLPVEAADLVAHSPSARAHVGTGMTLREAAEAALRYSDNTAGNLLLRAVGGP +EGITAFVRSLGDPVTRSDRWEPALNTAVPGDERDTSTPRALSADVRELVLGSRLDVAARE +LLRGWMLANTTGDARIRAGAPAGWRVADKTGTGGYGTAGDAAVLWPPQGAPIVLTVLTAG +DHPDAQPDEAVFAEVTRIVT--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6ALA8_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADXRFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKA---------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NEAU-S7GS2 TaxID=2202000 RepID=A0A2U8UZT0_9ACTN +---FASEFKKLERKYDARLGVYAVDTGNGREV-AYKDGERFSYNSTFKALAAGAVLRKHS +--PSAMNRVIKYSKDDLVATSPVSEKHVATGMSLSELCDAAVRYSDNTAANLLLEDLGGP +KRLEGVLKGIGDDVTRMERIEPKLSQWTPGDTRDTTTPRTLAKDLRAFVLGGVLDKGDRK +QLTKWLRTNTTGDEVIRAGMPKGWVVGDKTGAGTYGARDDIAVVWPPGRAPIAVAIMSNR +FKKDVDFDNKLIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=A0A498CGM0_9GAMM +----AKDFAALEVASGGRLGVTLLNTGTGWRT-GNRQDERFPMCSTFKFVLSAAVLHLAD +QGRLSLDRRVAVRQQDMLSHAPVTTRHIGKDVTVRDLCRATMITSDNPAANLLLGMVGGP +AGVTAFLRANGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRFVLGDVLKPASKQ +QLADWLIDNETGDTRLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ATVDDAGRNDVLRQVAV------ +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. AC27/96 TaxID=1841653 RepID=A0A1B9S3Y3_9RHIZ +---QQKRLAALESKYPGRICVSILDLASGRRV-DHRAGERMLICSTFKTLIAALVLTRVD +KGEEKFDRRIAYSKSDLVESSPATGAQLETGMTIAELCAAAMTLSDNTAANLLLASFGGP +KALTAFCRSLGDDITRLDRTEPTLNYDKPDDQRDTTTAAAMLENLRRLLFSDLLSAASRS +QLAAWLMTNKTGDTRLRAGVPKGWLAGDKTGTNGDGNANDIAVLWPTNRAPIIVTAYCEI +PGISADARNSIIAEIGRIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. Leaf154 TaxID=1736277 RepID=A0A0Q5KAT0_9MICO +--ATARAFASLERRYDARLGVAAVDTCSGRTL-VHRAGERFAFASTVKVFIAAAVLDGSS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTSVDRVEPDLNQATPGDRRDTTTPERFAADLRAVLLGDVLDAADRR +VLRDAMLGNTTGDATIRAGVAPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSR +ADAAAEPSDALVAAATRAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. 603 TaxID=2483798 RepID=UPI000F093356 +----AAELDALEERYAARLGVFAVDTGSGATV-EHRADERFAYASTHKALSAAAVLAGSG +--PDRLDDVVRYDASELVAHSPVTEQHVGTGLSLRRIAEAAVRESDNTAGNLLLEELGGP +AGFERTLEALGDDVTVAARRETALNEATPGDPRDTTTPRAFAQVLRAYAVDDALDTADRR +TLLRWMRGNATGDTLVEAGVPDGWRVADKSGAGGYGTRNDIAVVHPPGRSPIVVAVFSDR +GQPEADYDDDLIADAARAVI--- +>[subseq from] carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013313D32 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKXX--- +----AFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Photorhabdus luminescens TaxID=29488 RepID=UPI000B4D9241 +--RLATVVKQEEQTLNARIGVAVIDTASDKMV-SYRGNERFPLNSTFKALLCGVLLSEVD +KGKVALTDAIQFDKTELVEYSPVSEKFVAPAMNWQQLCSAAVSYSDNTAANLIAKKVGGP +VAMNLFFSGLGDSVTHLDRYEPELNSAIPGDERDTTTPVAVSQTLQKLTLGEVLKPSSRQ +QLVEWMRDDKVADALLRSVLPAGWKIADKTGAGDYGSRSIISIVWPKDSSPLIVAIYITQ +TEATIAQSNEAIARIGKIL---- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis pretoriensis TaxID=218821 RepID=A0A1H5RIJ1_9PSEU +----QADFTPLEREFDARLGVYAVDTGSGREL-LHRADERFGYASTHKAFSAAAVLQRTS +--VDGLAKVLKYTRADLQENSPVTEKHVETGISLRDAIDAALRYSDNTAANLLFRELGGP +PGLAAALRGIGDTTTHVDRIEPGLNDLAPGDVRDTSTPRAMATSLRAFTVGDALPPEKRQ +ILTDMMRANLTGAALIRAGAPEGWAVADKTGTGEYATRNDIAVVWPPGRAPIVLVVMSDK +KTEHADHDDRLIAAAAKLAF--- +>[subseq from] Beta-lactamase n=1 Tax=Oleiagrimonas sp. MCCC 1A03011 TaxID=1926883 RepID=A0A328T3H7_9GAMM +---IHTRLAALEKRHGGRLGVAMLDTASGRQI-GYRADHRFLMCSTHKVLVVAALLARVD +RGIEDLQRRVIFGHQALLDYAPVTRRHVGTPMTLEALCEAAITLSDNTADNLLLNALGGP +DAVTAYARSLGDRVTLLTRTEPALNLALPDDPSDTTTPQAMLSDLRDLLIGEALRPASRQ +RLLGWMRACQTGSRLLRAGLPRAWRCADKTGRGAANEIHDIGLIEPPHGKPVLVCAYYAG +SIAPEPARESVLADVGRLAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhizobium multihospitium TaxID=410764 RepID=A0A1C3TZF4_9RHIZ +----EAQLAALDSKHPGRICVSILDMASGKRI-EHRAGERILMCSTFKALAAALVLARVD +KGEEKLDRRIRYAKSDLVDGSPATKEHAGETMTIAELCAAAVTLSDNTAGNLLLASFGGP +EAITTFCRSMGDEITRLDRTEPTLNYDTPDDQRDTTTASAMLENLRRLLFTDVLTAASRS +QLAAWLITNKTGDVRLRAGLPKDWLVGDKTGTNGAGNANDIAVLWPANRAPILVTAYCEI +PEIAAGERNAIIAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_052 TaxID=2175655 RepID=UPI000DA6F504 +--ATTRAFDGLEGAHDVRLGVVAIDTGSGATV-THRAGERFAFASAAKVFIAATVLDDAS +--PADLDAVVPIEQRDLLSYAPVTSQHVGSGMTVRALLDAMLRSSDNTAANLLVARVGGP +SVVQQWLRGTGDQVTQVVRIEPEFNEATPGDDRDTTTPAQFAADLRTVLLGDALQPDDRE +LLVDTMAGTTTGDATIRAGVPTGWTVADKTGTGSHGVRNDVGIVTPPGGAPIVLVVMTSR +STADAEPDDALVAAATRTAVS-- +>[subseq from] Beta-lactamase n=1 Tax=Comamonas sp. JUb58 TaxID=2485114 RepID=A0A4R7FMV0_9BURK +--QFAKAMKALERSVGGRLGVSLLNTMTGQAL-GWRQDERFPMCSTFKMLLAGQVLSRVD +AGQEKLDAQVTFGRSALVEYSPVIEKFAGKAMSVEALCHAIVTISDNGATNLLLERVGGP +AGFTAYVRSLNDPTTRLDRIEPDMSESKPGDVRDTTSPLAMLTSMHALTLGKTLSPASRE +KLLGWMLANTTGDHCLRAGAP-GWKVADKTGSGP-GTRNDIGLLWAPGASPILVTSYLTE +SKAAPKARDAALASVAAEVVKLw +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB00455 TaxID=1703927 RepID=A0A1Q5N6F9_9ACTN +----VRELATLERDHSARLGVYARNTATGETV-LYRADELFPMCSLFKPLAVAAVLRDLD +RDGEVLARRIHYTEQDVVKHAPVTGRNLAAGMTIEQLCAATICQSDNAAGNLLLRELGGP +GAVTRLCRSLGDGVTRLDRWEPELNSAEPDRLTDTTSPRAIGRAYGRLALGDALSPRDRE +RLTGWLLANTTSTERFRKGLPADWTLADKTGGGQYGTNNDAGITWPPHRAPIVMAVLTTR +HQPDAAADNPLVAAAAALLA--- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bradyrhizobium sp. YR681 TaxID=1144344 RepID=J3I3P1_9BRAD +------ELETYERESGGRIGVYAENLATGAKI-AWRAEERFVMCSTFKASLAACVLARVD +RGEEQLSAMIPYSKADLLEYAPVARQNIPAGMSVAEMCKAIVELSDNTCANLLLARIGGP +PALTAFWRSLDDTISRLDHNEPELNRSPPGAPHDTTTPAAMAGNLKRLVTGEALSPASRA +QLTDWMVNCKTGANRLRAGLPAGWKIGDKTGNNGKDASGDIAVAWPKSDAPILIAAYTQG +GTPSTAQIEAVFAHIGRMVTE-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000C15FEE9 +-----GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2Z3YEZ3_STEMA +----ATDFATLEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRASIITSDNTAANLLFGVVGGP +PAVTAFLRTSGDAVSRSDRLEPELNSFAKGDPRDTTTPGAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces aureocirculatus TaxID=67275 RepID=UPI0004C9B5F2 +----ARAFKELEREFDARLGVYAVDTGTGREV-AYNDGRRFAYNSTFKALAAGAVLRENT +--PAGMDKVVKYSKEDLIANSPVTEKHVDTGMSLRALCDAAVRYSDNTAANLLFDELGGP +EGLDADLEKLGDHVTRVERVEPFLSRWVPGEKRDTSTPRALVKDLRAYVLGDVLDEPDRA +LLARWLKTNTTGDNVIRAGVPKTWVVGDKTGTGSYGARNDIAVVWRPDAAPLVVAVLSHR +ADKDATPDDRLIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia thermophila TaxID=1848 RepID=UPI001161161B +------------ARRGVRLGVHAVATADGREL-AHRADERFAHCSIVKVLAAGAVLDRFP +--IEQLDRRLPVEAADLVAHSPSARAHVGTGMTLREAAEAALRYSDNTAGNLLLRAVGGP +EGITAFVRSLGDPVTRSDRWEPALNTAVPGDERDTSTPRALSADVRELVLGSRLDVAARE +LLRGWMLANTTGDARIRAGAPAGWRVADKTGTGGYGTAGDAAVLWPPQGAPIVLTVLTAG +DHPDAQPDEAVFAEVTRIVT--- +>[subseq from] Class A beta-lactamase n=1 Tax=Lentibacillus salicampi TaxID=175306 RepID=A0A4Y9A931_9BACI +-----EKFLQLENEFDAQLGVYAMDTGTSQTI-EYRPNERFAYSSTFKPLAASILLKQNN +--IEDLEKVVTYTNNDLVTYSPVTEKHVDTGLTLLEISEAAIRKSDNTAGNLLLEAIGGP +DKFEQALRDIGDDVTHPERYETELNEFTPGNNRDTSTPRAMATNLKKIALSDFLPDDKRE +LLIDWMTGNESGDPLIRAGAPEKWTVVDKSGAGTYGTRNDIAIVWPPKKEPIVIAIMSRH +DTEDAEYDDSLIAKAAEITLNAf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CG 926 TaxID=1882405 RepID=UPI000D6B8504 +-------LRALEREYGARLGVYALDTATGRTV-VHRADELFPMCSVFKTLAAAAVLRDLD +HDGAHLAKRIHYTPQDVTDGGSITEKNIANGLTVAELCSAAIAQSDNTAGNLLLRELDGP +TAITRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLTIGDALDSGDRE +RLNRWLLSNTTSGDRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPMVLAILSTM +PEATAPRDNTLIARTAKLLAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. 1(2017) TaxID=1404888 RepID=UPI00140F0D39 +------ELAAYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEERLAAMISYGQADLLEYAPVAKQNLAAGMSVADMCKAIVELSDNTCANLLLARIGGP +AVLTAFWRSIGDTTSRLDHNEPELNRSPPGDSRDTTTPAAMAGNLRRLVLGEALSPASRA +RLTEWMVGCKTGANRLRGGLPANWKIGDKTGNNGKDASGDIAVAWPRADTPILIAAYTQG +GTPNPAQIEAAFARIGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_058 TaxID=2175635 RepID=UPI000DAA1CBD +--ATARAFAALERQYDARLGIAAVDTGSGRTI-VHRAGERFAFASTVKVFIAAAVLDASS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR +ADAGAEPSDALVAAATRTAV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces atratus TaxID=1893 RepID=A0A2Z5JMP5_STRAR +---AVRKLRDLEREHAARLGVFGWNTVTGRSV-LHREEERFPMCSTFKTLAVGAVLRDLD +HDGTFLSEVIHYTKQDIKRGAPVTGENLAHGMTVEDLCGAAISYSDNTAANLLMERLCGP +TSVTRFCRSIGDSVTRLDRWEPELNSAEPGRVTDTTSPRAIGKTYAQLVLGGALEAGDRK +RLTGWLLANTTGGKRLRAGLHEDWSVGDKTGTGSYGTTNDVGIVWPPGQGPIVMAVLSTK +HDADSEADDPLIAHAAAILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium diazoefficiens TaxID=1355477 RepID=UPI000428C8CA +------ELEAYERESGGRIGLYAENLATGAKI-AWRADERFVMCSTFKASLAACVLARVD +RGQEQLAAMIPYGQADLLSYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRIDHNEPEVNKSAPGDPHDTTTPAAMAGNLRRLVTGEALSPASRA +QLTEWLVGCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWPKDTAPILIAAYTQG +GSPTAPQIEAVFARIGRMVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Gracilibacillus saliphilus TaxID=543890 RepID=UPI0013D28312 +----DEEFAQLEDEFEAQLGVYAIDTGENQIV-EYNPDERFAYASTFKVLAAAILLKQNE +--IKDREKAVTYSKDDLVTYSPVTENHVDTGMTLLEISEAAIRKSDNTAGNLLLEALGGP +EEFQALLRDLGDDVTEPERYETELNEFMPGNKSDTSTPKVLATNLKKIALEDFLPNDKRE +LLIDWMKGNATGDTLIRAGLPEEWVVGDKSGAASYGTRNDIGIVWPPNREPIIIAVMSRH +NTKDAEYDDELVAKAARIIFD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1W6ALB5_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKA---------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas sp. J35 TaxID=935852 RepID=UPI00048CB86D +---TAADFAALEAASGGRLGVSLLDTATGQAR-GHRQDERFPMCSTFKALLSAAVLAGAD +RGQWSLDRRLPVGEGDLVPHSPVTRRHVGKDLTVRDLCRATMTTSDNAAANLLSGLIGGP +AALTAFLRAHGDAVTRNDRLEPVMNGFAPDDPRDTTSPGAMAASMARFAVGDVLAPASRQ +QLADWLIDNGTGDACLRAGLGPRWRVGDKTGSNGVDTRNDVAVLWPLDGRPWVLAAYLQG +ATVDSDARDAVLARAARLA---- +>[subseq from] Beta-lactamase n=1 Tax=Bordetella pseudohinzii TaxID=1331258 RepID=A0A0M7G847_9BORD +--DAQRQLARLEAREGGRLGVSLLDVQSGYAI-AYRADERFALCSTFKLLAVGAVLTRVA +RGEDDLSRPMRLSAADIVTYSPVTQQRLNEGMTLGQLCEAALLWGDNTAANLLLSTIGGP +PGLTAYARALGDGVTRLDRLETALNEARPGDERDTTTPAAMLGNLRQLVLGDVLPAPERE +RLRDWLMQCRTGRERLRAGLPAAWALAHRSGAGGHGSCNDIGVAWPAPAAPVLISAYLTE +SPLDLPGRERVLAEAARILAH-- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus clausii TaxID=79880 RepID=A0A268S5Q3_BACCS +-----AVFKALEEEYAARLGVFALDTGTGQTV-SYRADERFTYASAHKPLAVGVLLQQKS +--IEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANLIFDEIGGP +EGFKEGLRAMGDTVTEPERIEPELNNVEPGEIQDTSTPEALAKSLQEFTLGEALPADKQE +LLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILWPPEKEPIILAILSSK +DEKDAEYDDELIAKATEEVI--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=bacterium TaxID=1869227 RepID=A0A4Q3WRE7_9BACT +--TVVAKLAKLEKSLDGRLGVYAFDTATGAQL-HYRADERFPVNSTFKALLGAAILDRSE +HEVGFLERRIRFSNSDLVTHSPVTGEHLADGLTVAQLCAATIQTSDNTAANLLMKILGGP +SGVTAYARSIGDHKFRLDRWETELNTAIPDDLRDTSTPKAMAQSLRRVTVGHALEAEQRQ +RLITWLRGSTTGAKRIRAGVPKNWIVGDKTGTGEYGTAHDIAVLWPPRRRPIV------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. A23 TaxID=2606593 RepID=UPI001278AF80 +------DFAPLEREFDARLGVYAVDTGSGREL-AHRADERFGYASTHKAFSSAAVLQRTS +--LDGLAKVLKYTRADLQPNSPVTEKHVATGISLRDAMDAALRYSDNTAANLLFGELGGP +QGLGAALRAIGDTTTHVDRTEPGLNDLAPGDLRDTSTPRAMATSLRVFTLGAALPPEKRA +VLTDMMRANTTGAAVIRAGTPAGWTVADKTGTGDYATRDDIAVVWPPGRAPIVLVVMSDK +KAKDATADDRLIAQAAKLVF--- +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella genomosp. 7 TaxID=1416805 RepID=UPI000B9EEC97 +--TVAETAARVEARLGGRVGVALQRLGEPAVA-LYRADERFPMASTFKALACGALLAKVD +AAEQSLDTVVLYGPETLVTYSPVTAQHVGKGMTLAQLCHATITLSDNTAGNLVLRRIGGP +AGLTAFLRSTGDEMSRLDRWEPELNEALPADPRDTTTPRAAAGTLGRLLFQGVLSPGSSH +QLEAWMIADQVADELIRASLPQGWGIGDKTGSGERGSRSIIAVIRPPHGKPWLASIYLTG +SSSRPQERNAAVAEIGRSMI--- +>[subseq from] Beta-lactamase n=1 Tax=Curvibacter sp. PD_MW3 TaxID=2027918 RepID=A0A2D0ICI7_9BURK +--EWTRALQELEARSGGRLGVAIRDTGRGAQL-LYRADELFPLCSTFKLLLAAYVLHRVE +QGAEGLERRVLYPASVLVAHSPRTAPHAEGGMTVAQLCDATLVISDNTAANLLLGRHGGP +QALTAWLRSLGDTQTRLDRYETELNSALPGDPRDTTTPQAMLATMDKLLLGSALGTASRA +QLLAWLRGNLTGDHALRAGFPNGWVVGDKTGSGDLGTRNDVGIAWPAEGAPLLVASYLTG +AQLTPAQRDGVHAEVARLA---- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. UNCCL17 TaxID=1449051 RepID=UPI0009DE8C6B +--ATARAFVALERRYDARLGVVAVDTGSGRTI-AHRAGERFAFASTNKVFIAAAVLDASS +--DTDLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTHVDRVEPDLNEATPGDRRDTTTPERFAEDLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWQVADKTGTASYGVRNDIAIVTPPGQEPIVLVVMTSR +ADPGAEPSDALVAAATRAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Ruegeria sp. Alg231-54 TaxID=1922221 RepID=UPI000D552973 +--PLTETVQSWERRLDARIGLLLYDPSNEWEV-SYRADELFPMSSTFKPLLCGAVLAEVD +AGTESLSDHVKYQTTDLVDYSPVTSKHVETGMTVGALCEATMTISDNAAANLLLRRLDGP +AGLTEFLRTNGDDITRLDRWETALNEATPGDPRDTTTPRAILATLDRLLFGRALSPASSA +QLRQWMIDDQVADGLIRAHVPDGWTIGDKTGAGGHGSRAIVAFLQTPEPRTYLAAIYLTE +SDAPFPERNAVLSDIGRAMI--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000E0ED1C3 +-----------------------LDSATGKHF-GQREDERFPMCSTFKFVLAAAVLRRVD +EGKLTLAQRVKIRASDMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP +QGLTAFLRGIGDTQTRSDRHEPEMNRFAQDDPRDTTTPAAMALTLRTLLLGDALQPASRK +QLSDWMIDNRTGDTCLRAGLPRSWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG +ASVDSDARDAALKAVAQAVASH- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI0009F3D982 +-----AGFERLERAFGARLGVYAVDTATGREV-AYRADERFAYASTHKVFTAGGVLQRTP +--VAELDRTVTYSRQDVVANSPITEKHVGTGMPLRAVMDATLRYSDNTGGNLLFRELGGP +AGLTAVLRGIGDTTTHVDRIETELNDTAPGDIRDTSTPRALAVSLRAFALGDALPEDKRK +ILVDIMRGNTTGDANIRAGVP-GWAVADKTGTASYGTRNDIAVVWPPNRAPIVLSVLTDR +STKDAQIDNALLAQATVATV--- +>[subseq from] Beta-lactamase n=1 Tax=Delftia sp. (strain Cs1-4) TaxID=742013 RepID=F6AWV3_DELSC +-qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ +QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP +QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA +LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE +CPADAPQCDAALAAAGKAAA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium guangzhouense TaxID=1325095 RepID=A0A4Q0RRI9_9BRAD +------ELESYERESGGKIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEDKLAAMIPYGKADLLDYAPVAKQNLSAGMSVADICKAAVELSDNTCANLLLARIGGP +AALTTFWRSIGDTMSRLDHIEPELNRSPPGDVRDTTTPAAMAGNLKRLVAGEALSPASRA +QLTEWMVGCKTGANRLRGGLPKAWKIGDKTGNNGKDASGDIAVAWPKLDAPILIAAYTQG +GTPNPTQFEAVFASIGRRVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. CC120222-04 TaxID=1378088 RepID=A0A239Q4H2_9GAMM +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP +PAVTAFLRASGDTLSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAIGYEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Virgibacillus soli TaxID=480284 RepID=A0A0Q9XY39_9BACI +----DADFAKLEEEFDARLGVFALDTGTGETI-SYRADERFAYASTHKALAVGALLQQIS +--IEDLNQKVIFAEGDLVNYSPITEKYVDKGMTLSELSEASLRYSDNTAGNLILKELGGP +DEFKKALKKIGDDITKSERFEPSLNEVKPGETHDTSTPKALATSLKAFTLEDELQKEKRL +MLVDWMKRSTTGDTLIRAGVPKDWEVADKSGAALYGTRNDIAIIWPPNENPIILAILSDR +ATEDADYDDKLIEQAAETVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-31 TaxID=1463898 RepID=UPI0004C71D4A +----QAELAELERRYGARLGVYALNARTGRTV-AHRAGERFAMCSTFKAFAAAAVLRDQG +-GRAPMDRVLHYPPHDSMANSPETDKHQATGMTVADVCAAAIQYSDNAAGNLLLREIDGP +AGLTRFFRSLGDEVSRLDRWEPELNAAVPGELLDTTTPQAIASVLERLALGGALAGADRE +RFVGWLKGNTTSGRRFRAGLPREWVVADKTGTGSYATANDVGVAWTTRQTPVVLAVLSSK +TMPDAPVDEALIADAASIVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae subsp. ozaenae TaxID=574 RepID=A0A378B1E3_KLEPO +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVAPAWP-------------- +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas TaxID=40323 RepID=A0A2G7S026_9GAMM +----ATDFAALEKACSGRLGVTLLDTGSGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDPALLDQRLPVRAQDILEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRASGDTITRSDRLEPELNSFAIDDPRDTTTPAAIAATLQRLVLGDALKPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWILTAYLQA +GAISFEQRAAVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_031 TaxID=2175653 RepID=UPI000DA80355 +--ATRRAFDGLEGAHDARLGVVAIDTGSGATV-THRAGERFAFASAAKVFIAATVLDDAS +--PADLDAVVPIEQRDLLSYAPVTSQHVGSGMTVRALLDAMLRSSDDTAANLLVARVGGP +SVVQQWLRGIGDQVTQVVRIEPDLNEATPGDDRDTTTPAQFAADLRTVLLGDALQPDDRE +LLVDTMAGTTTGDATIRAGVPTGWTVADKTGTGSHGVRNDVGIVTPPGGAPIVLVVMTSR +STADAEPDDALVAAATRTAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID5770 TaxID=2690308 RepID=UPI00136EC469 +---HRREFRALESAFDARLGVYAIDTGTGREI-AYRDRERFPYASTFKALAAGAVLRE-- +EGLGGMERVVRYTKEELVEPSPVTEKHVGTGMTLDALADAAVRYSDNTAGNLLFEELGGP +KGLQAVLRSLGDGVTRMDRIEPELGDWKPGEVRDTSSPRALAGDLRAFVLGDVLRAPERE +RLTTWLKTNLTGDETIRAGVPDTWVVGDKTGTATYGGRNDMAVVWPPDGAPIVMAILSTR +SGREAEPDNRLIARAASVVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI00099857E5 +hpDVTARLNALEAQHGARVGVFAHNLGTRQTI-RHRADERFPVCSLFKTLAAAAVLRDLD +RSGEVLSKRVHYTADDLVDGSAETEKHLTEGMTVAELADVAIRFSDNTAGNLLLRELGGP +TAITRFARSVGDRATRLDRWETELNSAEPWRITDTTTPYAIGRTYARLVLDDVLNRPDRE +LLTHWLLTNTTSDNRFRLTLPPTWTIADKTGAGSYGTNNNVGIAWTQKGTPVVLAVQTTK +PAQDAAPDNPLVAETARLL---- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. yr375 TaxID=1761906 RepID=A0A1H9LF45_9ACTN +------RFGDLEREHSARLGIFAHDTGSGRTL-AYRADERFPLCSVFKALAVSAVLRDLD +QAGEYLAERIHYTKDYVTAYAPITDEHVAGGMTVEELCAAALSHSDNGAANLLMRELGGP +AAVTRFARSLGDATTRLDRWEPELNSAEPWRTTDLTSPRAIGRTFARLVLGRALPPADRT +RLTGWMIANTTNTERFRAGLPADWVLADKTGGGQYGVANDVGIVWPPGRAPLVLAVLSTK +HASEGPSDNPLVARAAELVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium botulinum B str. Osaka05 TaxID=1407017 RepID=A0A0S6U3G4_CLOBO +--QYNSAFSQLESDYDVKLGIYAFDTEMNKEV-AYHADDRFAYCSTFKALAAGAVLKQDS +--LDELKKVVKYKKEDVLSYAPIAKDNVDKGMTIEEICNAAVRFSDNTAANLLFNHIGGP +SGFKSALNQLGDNVTQPARIEPELNEAMPGDIRDTSTPRQLATDLQAYTTGNILTDDKKR +ILIDWMTGNATGNTLIRAGAPDNWVVADKSGTGPYGTRNDIAIVMPPNKKPIIIAILSTH +HTKKAKYDDKLIAQVSKIVFDSf +>[subseq from] IMI-1 n=6 Tax=Enterobacter cloacae complex TaxID=354276 RepID=Q46991_ENTCL +-----DEIKDLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ +DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +NEKEAKHEDKVIAEASRIAID-- +>[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A0M1EST1_STEMA +-----ADFAALEKASGGRLGVAVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEQDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP +SALTAFLRGQGDSVTRNDRNEPDMNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHAGPAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces prunicolor TaxID=67348 RepID=UPI000375D818 +------GLRALEEQHTARVGVFAHHLGTKKTV-VHRADELFPMCSVFKTLAAAAVLRDLD +RHGEVLYKVVHYTEADLVDGSDQTRAHLAEGMTVEQLADVAVRFSDNGAGNLILRELGGP +TAVTRFARSLGDRVTRLDRWETELNSAEPDRITDTTSPRAIAGLYRKLVLGDALRRPDRD +RLTAWLLNNTTSAARFRAGLPASWTIADKTGSGDYGTANDVGIAWTEAGDPVVLAVLTTK +PTPDAPYDNQLVADTAKLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. HMWF023 TaxID=2056859 RepID=A0A2R7IJF2_9GAMM +----ASDFAALEKACSGRLGVTLLDTGSGRRL-GHRQDERFPLCSTFKSVLVATVLKQAE +RDPALLDRRLPVRAQDILEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRATGDTITRSDRLEPELNSFALDDPRDTTTPAAIAATLRRLVLGDALKPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWIVTAYLQA +GAISFEQRAAVLAQVGRIA---- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobiales bacterium Sp-1 TaxID=2608987 RepID=A0A6A7Y346_9RHIZ +----VAKFTAIEQAHGGRLGVVAVEAGTGRRI-AYRGDERFPLCNTFEILAAGAVLARVD +AGEEHLERRVIFHEDDVVEGSPATQGHVRPPLTLAEICAAATEYSDNTAANLMLRSLGGP +EGLTAFLRSLGDTESRVDRYEPELNDVKPGDPRDTTTPAAMAADLEKLLLGPVLSPTSRA +QLAAWMIACKTGLERLRAGLPADWKAGDRTGADGLLVTDDVAILWPPERPPILVAAYYAG +GAGAPRQQDAVLAEVGRIVAAAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. DK17 TaxID=186196 RepID=UPI000309B7D1 +--SLDATIDALEAQYSTRIGVTAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE +DGSTSLDKTVVIESGDLVENSPVTAAAVGAPMTLGQIAEAALTQSDNTAGNYLLREIGGP +QAITALARDVGDGGTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD +QLLEWMRASKTSDKRMRAGLPTGWTAADKTGGGGFGTANDAGVAWSPDGAPLVLAILTDS +LTQDAQGNNQAIADTTAAVIE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus galactosidilyticus TaxID=217031 RepID=A0A177ZRZ0_9BACI +----DADFAKLEEEFDARLGVFALDTGTGETI-SYRADERFAYASTHKALAVGALLQQIS +--IEDLNQKVIFAEGDLVNYSPITEKYVDKGMTLSELSEASLRYSDNTAGNLILKELGGP +DEFKKALKKIGDDITKPERFEPSLNEVKPGETHDTSTPKALATSLKAFTLEDELQKEKRL +MLVDWMKRSTTGDTLIRAGVPKDWEVADKSGAALYGTRNDIAIIWPPNEDPIILAILSDR +ATEDADYDDKLIEQAAETVI--- +>[subseq from] Beta-lactamase L2 n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=BLA2_STEMA +----ATDFAALEKAVRGRFGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RQPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRSIGDAVSRTDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQLASRQ +QLADWLIDNETGDACLRAGLGKLWRVRDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] Class A beta-lactamase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=A0A1D8IH59_9BURK +--TFQQSLAKLEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVQGYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRGLGDTVTRHDRYEPELNRPHPSEPQDTTTPRAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Variovorax sp. BT01 TaxID=2135732 RepID=A0A4R1VPU2_9BURK +-kEAAAQLADIERRSGGRMGLYAIDTASGRTL-AHRGAERFAMASTFKLLLASAVLHLED +RQPGSLDQRLPVRQADLIAHSPITSKHLEDGITARQACEATVTVSDNGAANLLFPMIGGP +QGLTRFLRECSDSVTRMDRTEPTLNTNLPNDLRDTTTPQAMAQTMRRLLVGNVLTPTSRD +QMNAWLQGATTGFARLRAGLPKDWRTGDKTGTGENGAANDVAITWPTGRAPILMAVYLSG +STQPGAVLDATHAQAAAVVAS-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomycetaceae bacterium MP113-05 TaxID=1380770 RepID=V6L4G2_9ACTN +--DIAGRLRELEQRHSARLGVFAHDTATGRDV-RYRAHERFPMTSTFKTLAAAAVLRDLD +RDGEFLARRVHYTERAVEKYAPVTGENLARGMTVEELCDAAIRFSDNAAANLLLRELGGP +RAVTRFCRSIGDRITRLDRWEPELNSAEPWRRTDTTTPRAVAGTYARLTLGDALDRGDRR +RLTRWLLGNTTSDAKFRTGLPGDWTVADKTGGGEYGTNNDVGLTWPPGRPPIILAVLTTR +FAPDAERSDPLVAETAALLA--- +>[subseq from] carbapenem-hydrolyzing class A beta-lactamase IMI-19 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=UPI0010C2FDF8 +------DIKNLETDFNGRIGVYALDTGSGKSF-TYKANERFPLCSSFKGFLAAAVLKRSQ +DNQLSLNQIVNYNTRTLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTIALGNILSEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +YEKEAKHEDKVIAEASRIAID-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. XY66 TaxID=1415563 RepID=UPI0006AEB0AE +----VRRLRALEREYGARVGAYARDTGTGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD +RDGEFLARRIHYTQGDVTAGGSVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP +TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE +LLTRWLVSNTTSDDRFRAGLPRNWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK +PDAAAPRENALVARAAEVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. (strain R39) TaxID=72570 RepID=Q60225_ACTSP +-eDLSGEFERLESEFDARLGVYAVDTGTGEEV-FHRADERFGYASTHKAFTAALVLGQNT +--PEELEEVVTYTEEDLVDYSPITEQHVDTGMTLLEVADAAVRHSDNTAANLLFEELGGP +EGFEEDMRELGDDVISADRIETELNEVPPGETRDTSTPRAMAGSLEAFVLGDVLEEGPRD +VLTEMLLNNTTGDELIRAGVPEDWRVGDKTGGGSHGSRNDIAVVWPPEDDPIVIAVMSTR +EQEDAEFDNALVSGATEVVVE-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces alboflavus TaxID=67267 RepID=A0A1Z1WJM7_9ACTN +---HRRRFADLEREFDARLGVYALDTATGATL-AHRADERFAFCSAFKALAAAAVLDGNP +--LSHLDKRVTYSRADLMKHAPVTARHVDTGMTIRQLCDAAIRHSDGTAGNLLLRDLGGP +DRLTAYARGLGDKVTRMDRVEPAITQATPGDPRDTSSPRAFGGTYQKIVIGDALPGRKRA +FLLDLLQRNVTGAERIKAGLPRGWTIADKTGTGDHGTLNDIAVLWPPRSPPVLLAIMTSK +AAKDAPYDQALLAEAAEYVT--- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A0A0NJS0_STRRN +------RMRELEREYGARLGVFALDTGTGRAV-THRADERFPICSVSKTLAVGAVLRDLD +RDGEYLARRIRYTEDDVKTHIPITGTNIANGLTVEELCAAAISYSDNGAMNLLLRQLGGP +TAVTRFCRSLGDGITRLDRWEPDLNSAEPGRVTDTTTPRAIGRTYAGLAVGRALDTGDRE +RAAGWLVANTTGDARIRAGVPGGWTVGDKTGTGRYGTTNDVGIAWPTDRAPIALAVLSTR +PEQDAEAVDPLIAKATALAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus opacus TaxID=37919 RepID=UPI0002A22007 +---LDATIDALEAQHSTRIGVTAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE +DGSTSLDKTVVIEPSDLVENSPVTAAAAGTPMTLAQIAEAALTQSDNTAGNYLLREIGGP +QAVTDLARDVGDGSTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD +QLLEWMRASKTSDKRMRAGLPTGWTATDKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS +LTEDAQGNNQAIADTTAAVIK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. NWU339 TaxID=2185284 RepID=A0A2U2ZDK6_9ACTN +--EIMRRLRDLERRHSARLGVYARDAATGRTV-RYRAHERFPVCSLFKTLAVAAVLRDLD +RDGEFLARRIRYTGKDVTDYAPITGKNLADGMTVAELCAATICHSDNAAGNLLLRELGGP +TAITRFCRSVGDRTTRLDRWEPELNSAEPWRTTDTTSPSAVGRTYARLVLGTALAVGDRE +RLTDWLLANTTGGAKLRAGLPSDWTVADKTGGGMYGTNHDVGIAWPPGRSPLVMAVLTTK +HEPDASPDNPLIAETATLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas sp. GW2 TaxID=1211114 RepID=UPI0002EFFDD1 +-----PDFAALEAASQGRLGVAVLEAGNGRYLaGHRADERFPMCSTFKALLAAAVLARAD +RGALDLDERLPVRAADLVPHAPVTRRHVGKDLGVRDLCRAIVTISDNTAANLLFARIGGA +AALTAVLRGLGDTVTRSDRLEPEMNGFVPGDPRDTTSPRAMATSLGRCVAGVVLAPASRL +QLADWLIDNTTGDDCLRAGIGPEWRVGDRTGSNGTDIRNDVAVLWPLGGSPWVVAAYLEG +SRVDSAARDAVLARAGQLAV--- +>[subseq from] Beta-lactamase n=2 Tax=Nocardia nova TaxID=37330 RepID=W5T6V8_9NOCA +-nSAQDRLRGLEAGLGGRIGVYAVDTGTGRIR-AYRADERFPFASTYKALAAGAVLERNK +--PEALDSRIHYSRDDLVAHSPITGQHVDDGMTLREILDAAVRYSDNTAGNLLFRAVGGP +KPLQQQLHEIGDDATSMDRTETDLNQTAPGDIRDTSTPRALGADLRYFALDAAVSQENRR +ILGGLLRANTTGDTLIRSIAPAGWDVGDKSGSGTYGTRNDIAVLWPPGRAPIVLAVLTTR +DRPDAEYDDTVVARAAAIAVT-- +>[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces sp. CNQ431 TaxID=1571532 RepID=UPI00053D09A5 +--DAERRLARLERASGARLGVYAYDTGSGRAV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +TAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLALGDALNPRHRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLTAK +TGEDAVRDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. PVA 94-07 TaxID=1223307 RepID=V4IXJ6_9ACTN +--DAERRLARLERASGARLGVYAYDTGSGRAV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +TAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLALGDALNPRHRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLTAK +TGEDAVRDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=A0A3S4A0P0_9ACTN +--DAERRLARLERASGARLGVYAYDTGSGRAV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +TAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLALGDALNPRHRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLTAK +TGEDAVRDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=A0A068F868_ECOLX +---VTDTIQSTEDHIKGRVGFTEIDFLSGKVLsSHRREERFPMMSTFKVLLCGAILVRVD +KGLEQLERRITYNKHDLDDYSPLTSQHIADGMTVSELCNAAITTSDNTAANLLLSTIGGP +EGLTHFLRSTGDSYTRLDRHEPSLNEAKPGDERDTTTPAAMAQTLQKLLNGSVLTEKSRK +KLISWMQEDKVGGPLFRSVLPAGWMIADKTGAGDHGSRGIVALLGPGGKPSRIVVLYITN +THSSMNELNEHIAGIGDSVIKNw +>[subseq from] Beta-lactamase n=1 Tax=Paracoccus gahaiensis TaxID=1706839 RepID=A0A4U0R337_9RHOB +--TITEAARAIETDLGGRVGVSLRQPGGAGAT-GYREDERFPLSSTFKAPLCGAILTLVD +AGEDQLDRVIGYSPGDLVTYSPVTETR--DAMTVAELCEATITLSDNTAANLLLDRLGGP +EDFTEYLRAIGDDTTRLDRWETDLNEAAPGDPRDTSTPAAMTATLETLLFGPVLSDAAQR +QLEAWMQADQVADDLIRASLPEGWEIGDKTGAGGYGSRSIIAVIRTPQGDPWLASVYLTG +NEADMPTRNRAIARIGAAIVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. SID8362 TaxID=2690346 RepID=UPI001414EBA0 +----QPDFAPLERDFDARLGVYAIDTGSGREI-AHRADERFGYASTHKAFSTAAVLQRTS +--MAGLAKVLPYTSADVQPNSPVGEKHAGTGLSLRDAIDAALRYSDNTAANLLFRELGGP +AGLAAALRGIGDTTTHVDRIEPGLNDLAPGDVRDTSTPRAMAADLRAFALGTALPAEQRT +FYTDTMRANRTGDALIRAGTPAGWTVADKTGTGAYATRNDIAVVWPPGRAPIVLVVLSDR +KTADADHDDRLIAQAAKLTLDTy +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. M39 TaxID=1825094 RepID=A0A178XH41_9PSEU +----QPDFAALEKAFDARLGVYAIDTGDGREV-AYHADDRFAYASTHKVFNAAAILHRGD +----DLTRTVTIRQSDLVPNSPITEKHIGEQMSLQSVLDAALRYSDNTADNLMFREIGGP +AGLAAELRRLGDTVTRVDRIEPALNETSPGDVRDTTTPRAWSKDLRAVALDSGLPADKRA +VLTKIMRANTTGAHVIRAGVPADWQVADKTGSADYATRNDIAVLWPPHRAPIVLAVLSDR +RQKDAKTDDKLIARAAAAVVK-- +>[subseq from] Beta-lactamase AXC-2 n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=A0A346DAP7_9BURK +--TFQQALAKLEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVQEYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRGLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella genomosp. 13 TaxID=463040 RepID=UPI000A32897F +--ALDQALADLEKQSRGRLGVALTDTATGQVA-SYRGDERFLMLSSFKTLAAAYVLARAD +RGEDQLTRRMPIAESDLVEYAPVTKQHVGPRMTLAELCHATVTTSDNTAVNLMHRSYGGP +QALTRFIRSLGDTVTRHDRYEPELNVPHPTEPMDTTSPHAMNRTLGALLFGKALKPESRE +LLQSWLLANTTGGKRLRAGLPADWKVGEKTGTYSRVGSNDAGFARAPGGSPIIVSVYLET +TAIPMPERDRIIADVGRQVA--- +>[subseq from] Beta-lactamase n=2 Tax=Roseovarius mucosus TaxID=215743 RepID=A0A1V0RSP0_9RHOB +--HLAATIDRIEQELDARVGVVIRDSGSDWTV-SHRAEERFLMASTFKTMLCGAVLHRVD +EGDLDLEERIAIEAAEVLEYAPVTEKMVGETMSVGELCHAALDMSDNTATNLLIDRIEGP +QSVTAFLREIGDPVSRLDRREPDVNTFAPDDPRDTTTPEAMVSTMETLLTGGALSPQSRA +LLVDWMSDGGVTGALIRASTPAGWHVADRSGSGNF-NRNIVAMVTPPDREPYFIAIFLSD +ADADFNTRNGAMIELSKAVMQ-- +>[subseq from] Uncharacterized protein n=2 Tax=Xenorhabdus hominickii TaxID=351679 RepID=A0A2G0Q4X7_9GAMM +--QIIDQLAILEKNANGHLGAVLIDTADHSVI-SYRADQRFPLCSTSKFMAVSAILKKSE +TDNHLLNQRIHYQQSDLVEYSPITEKHLKNGMTLGELSAATLQYSDNSAMNLLLDQLGGP +NEVTKFARTIGDNHFRLDRKEPELNIVEPGDERDTSTPQAMADSLYNLTLGNALAAEQQE +LLANWLKGNTTGGTSIRAGVPEDWLVGDKTGRCDYGSTNDIAVIWPTNKAPLILVTYFTQ +PNKKAIARPDVLATAARIMTQ-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces atratus TaxID=1893 RepID=A0A1K1ZFM6_STRAR +-----GQLAALERKFEARLGVYALATGTGATI-THRADERFAFCSTFKGLAAAAVLHRNP +--LSHLDTVIRYTEGDLMKSSAITRQHVATGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP +ARFTAYVRSLGDTVTRMDRIEPTIAQATPGDPRDTTSPRAFGTNYRKILLGDALPTDKRT +FLRHLLERNGTGAQRIRAGVPRGWNVADKTGTGDYGTLNDIAVVWPPNAAPLVIAIMSSK +ATKDAKYDQALLAEAAAYVVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00048E2A73 +----DREFRRLEQRFDARLGIYAIDTGTGRTV-RYQADERFAYASTYKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPVTEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDEVTDAARYETALNEATPSDRRDTSTARALTEDLRQYAVDDALEPADRD +ILNAWLRGNTTGGALIRAGVPDGWVVGDKTGAAGYGTRNGIAVIWPPDRAPIVLAVLSSR +DERGASYDDALIAQATEVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TP-A0875 TaxID=552354 RepID=UPI000A43160D +-----ARLRELEERYAARLGVYAHDTATGRTV-RYRADERFPLCSVFKTLAVAAVLRDLD +RDGEFLGRNIRYTERDVTEHAPVTGEHLAAGMTVGALCSAAIRHSDNAAANLLLAELGGP +SAVTRFCRSIGDGTTRLDRREPELNSAEPWRTTDTTSPEAVGRSYARLLLGTALGRGDRA +LLTGWLLANTTGDEKLRAGLPADWAVAEKTGSGGYGTGHDVGVAWPPGRAPLVLAVLTSG +TEPDAVADSALIAGTATLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02009 TaxID=1703938 RepID=A0A1Q5J6T2_9ACTN +--DLLARLRELEERHSARLGVFAHDVRSGRSV-AYRADEHFPMCSVFKTFAVAAVLRDLD +RDGSFLARRIRYTAADVERWSPKTEENLAHGMTVAELCDATLRFSDNTAANLLLRELGGP +TAVTRFARSIGDRTTRLDRWEPELNSAEPWRRTDTTTPRAAGRSYGRLLLGDALPVEDRE +RLTAWMLGNTTSGERFRKGLPADWILADKTGGGRYGGNNDAGVTWPPDGGPIVLTVLTTR +FVEDAAPVDPLVADAAALVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas viridiflava TaxID=33069 RepID=UPI0013DF92C0 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSHGIIAALGPDGKPSRI------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseorubiginosus TaxID=67304 RepID=UPI000F4BBD6E +--DVSTRLRALEQRYDARLGVFAHRPTTGRSV-RFRADERFPMCSLFKTLAAAAVLRDLD +RHGEVLARRIHYTEADLVQGSDQTAAHLAEGMTIAELAEVAITHSDNTAGNLLLRELGGP +TAITRFARSLGDGVSRLDRWEPELNTAEPWRLTDTTSPYAIGRTYGRLVLGDALNRRDRD +LLTHWLLSNTTSVDRFHAGLPKTWRIADKTGSGSYGTANDVGVVWTGKGDPLVLSVLSTM +PEPDAVRDDALVADAAAVVA--- +>[subseq from] Beta-lactamase n=1 Tax=Geodermatophilus obscurus TaxID=1861 RepID=A0A1I5H311_9ACTN +---VSGEFATLEERFDARLGVFAVDTGSGATI-EHRADERFAYASTIKALAAGALLAQTS +--PADLARAVPIAAADLAPYSPVTETRVGGSMTLAELCDAAVRFSDNSALNLLLRELGGP +AGLDAALERVGDTVTEVVRDEPGLNSAVPGDPRDTTTPRALAGSLRAYALD-AAAPEDRE +QLVDWLRRNTTGDALIRAGVPDDWDVGDKTGTGAYGTRNDVAVVIPPGRSPIVLAVMSSR +DEPDAEHDDALIAETTRVVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Marinobacter subterrani TaxID=1658765 RepID=UPI0009E60D7F +-kDISNQLRQLESQYGGRLGVALMNCSTGAVA-SHRGDERFLFNSTGKLFIAAAVLAQVD +RGDAALDLRLVVSESDLGGWTPITEKHLGEPMTVAELCQAVVAWSDNAAANVLVRFVGGP +EAVTAFLRSIGDDVTRLDRYEPELNEDHEGDKRDTTTPLAMMKTLQRLLLGEALSPSSRH +QLAAWMIEGKTGDARLRAGMPSSWLIGEKTGTNGVGNANDIGIAWPADRGAVVAVAYTFG +PKASKEQRDDVIAMIGAMA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces luteocolor TaxID=285500 RepID=UPI000852A75C +--RLKGRFEALEREHGGRLGVFALATGTGATL-AHRADERFAFCSTFKTLAAAAVLHHNP +--LGHLDKRVTYTAADVDSISPITEKHIATGMTVRELCDAAVRHSDGTAGNLLMRDIGGP +RRLTAYLRGLGDTVSRMDDYEPELNDVPPKDPRDTTTPRAVAAVYRALVLGDALSAAKRA +LLKDWLLRNAVGATRIRAGLPKGWTVADKTGTGNWGRANDIAVIWPSGRDPLVLAVMTDR +PGRDARTKDALLAGAAKAAAN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Hydrogenophaga sp. IBVHS1 TaxID=1985169 RepID=A0A1Y2QT27_9BURK +--NLRDSLREIEATARGRLGVHIIDTATGREH-GWRSDERFLMLSSFKLLASALVLDRVD +RGVEKLERRIRYRKQDLVSWSPVTERHVGGALSLAQLCEATITTSDNTAANLILASYGGP +AALTTYVRGLGDTVTRHDRIEPMLNNAASGEPLDTTSPRAMAHTVRALLLGDALKPSSRE +QLMNWLLANTTGGKRLRAGLPAGWRIGEKTGTAND-DANDIGMAMPPQRAPIIVTAYLAE +SRTDAATREAALASVGRLLAQ-- +>[subseq from] Class A beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. SID10815 TaxID=2706027 RepID=A0A6B2V431_9ACTN +--RAETELTELERRFGGRLGVYAMDTGTGEEV-RHRADERFLMCSTHKALTVAAVLRAHQ +DRPALLKQVIHYRRSDLLDYAPVTSRHVGEGMTVAALCRAAVTRSDNAAANLLLRTVGGP +AAVTRFVRTLGDPVTRLDRDEPHVNEA--DGVLDTTTPAHFGASVRALTLGDALEPRGRG +QLLAWLDANTTGDRAIRAGCPKGWRIGDKTGSGDHAESNDIAVIRPPRHAPLVLAVFTAP +DDPKSTTGQHTIAEAARIVT--- +>[subseq from] Class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_047 TaxID=2175654 RepID=A0A2W1ZPV6_9MICO +--ATRRAFDGLEGAHDARLGVVAIDTGSGATV-THRAGERFAFASAAKVFIAATVLEDAS +--PADLDAVVPIEQRDLLSYAPVTSQHVGSGMTVRALLHAMLRSSDNAAANLLVARVGGP +SVVQQWLRGIGDQVTQVVRIEPELNEATPGDDRDTTTPAQFAADLRTVLLRDALQPDDRE +LLVDTMVGTTTGDATIRAGVPTGWTVADKTGTGSHGVRNDVGIVTPPGGAPIVLVVMTSR +STADAEPDDALVAAATRTAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Kurthia sp. Dielmo TaxID=1033738 RepID=UPI00112298E5 +---PQQDFKELEKKYDARLGIYVIDTATNKKI-AYHANERFAFTSTYKALAAGVLLQNAS +--LEQLETVILYTKDDLVAYSPVTELYTDTGMTLREISEAAVRYSDNTAGNLLFHAIGGP +KGFEQSLRKMGDKTTYANRFETELNTAIPGDKRDTSTAKALAIDLKKYTIDSTLSIEKRQ +LLLDWMTDNKTGDALIRAGVPTDWKVVDKSGAGSYGTRNDIAVVFPPNRAPIVLAILSSR +SEQNATYDNQLIEEATRVIIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinoplanes atraurantiacus TaxID=1036182 RepID=UPI000BE28CDD +------RFGELERRFKARLGVYAVDTGNGRTL-AHRADERFAHASTFKALLAAVLLRDLT +--DADLGRVVTYTQANLLEWAPVTSRHVATGMTVEALIDAAVRHSDNTAANLLLREVGGP +AGLQRELRKINDRVTYVSRTEPSLNEATPGDQRDTSTPRALGTDLRRLVLGDDLPPPRRQ +KLAALLRGNTTGGPYIRAGVPAGWTVGDKTGGGGYGTRNDIAVVWPPTGSPLVIAVQSDR +GVRDAASDDALIAEAAKAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora costi TaxID=1530042 RepID=A0A3B0ACY9_9ACTN +----HRRLAELERRFDARLGVYGLATGTGDTV-AHRPDERFAFCSTFKGLAAAAVLDRRP +--LARLDTTVRYTEADLMASSAITRRHVRTGMTLRALCDAAVRYSDGTAGNLLLRDLGGP +AALTTYLRRLGDTVTRMDRIEPHIVEATPGDPRDTTSPRAIGTDYQRLLLGDALPDDKRA +FLRDLMERNATGARRIRAGVPRGWTVADKTGTGDYGTVNDIAVVWPPASPPLVIAIMSSK +AGRDAEYDQALVAEAAAYVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 57 TaxID=2035243 RepID=UPI000EAB5F25 +---PQARLRELEKRHGARVGAFAHNLATGTTA-RHRAGERFPMCSVFKTLAVAAVLRDLD +RDGGTLARRLHYTAADVVAGGSITVKNVAAGMTIAELCDAAIRYSDNLAANLLLRELGGP +TAVTRFCRSVGDPKTRLDRSEPDLNTAEPWRRQDTTTPAAIARTYARLTLGDALDDDDRT +RLTAWLLGNTTSAKRFHEGLPDDWSIADKTGTGSYGTANDVGISWTPEGVPVVLAVLTTK +PAQDATPDDALVAATAKVLAD-- +>[subseq from] Uncharacterized protein n=1 Tax=Bordetella genomosp. 13 TaxID=463040 RepID=A0A1W6Z973_9BORD +--ALDQALADLEKQSRGRLGVALTDTATGQVA-SYRGDERFLMLSSFKTLAAAYVLARAD +RGEDQLTRRMPIAESDLVEYAPVTKQHVGPRMTLAELCHATVTTSDNTAVNLMHRSYGGP +QALTRFIRSLGDTVTRHDRYEPELNVPHPTEPMDTTSPHAMNRTLGALLFGKALKPESRE +LLQSWLLANTTGGKRLRAGLPADWKVGEKTGTYSRVGSNDAGFARAPGGSPIIVSVYLET +TAIPMPERDRIIADVGRQVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia anaemiae TaxID=263910 RepID=UPI0007A3C103 +------HLTELEQKFAARLGVYALATGTGTTI-AYRADERFAFCSTFKGLAAAAVLQRNP +--LSHLDVTVTYTEADLLRNAAITPQHVASGMTIRELCDAAVRYSDGTAGNLLLRDIGGP +GELTAYARSLGDTITRMDRIEPAITEATPGDPRDTTSPRAIGTDYQKIVLGDALPEEKRA +FLRGLLERNATGAQRIRAGVPQGWTVADKTGTGDYGTLNDIAIVWPPNAAPLVIAIMSSK +FTRDAEYNQALIAEAAAYVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptacidiphilus albus TaxID=105425 RepID=UPI0005AA3BF8 +---ITARLRALERAHSARLGVFAADTVTGRTV-GYRADELFAMCSTSKTVTVAAILRDLD +RDGRFLAERVRYTEQDVTGYAPITGLNLAHGMTVADLCAAAIEYSDNTAANLLLREIGGP +PAFTRFCRSIGDGVTRLDRWEPALNSAEPGRVTDTTSPRAIGRTYARLVLGDVLGARHRE +RLTGWLLADTTSGNRFRAGLPKDWTLADKTGTGGYGTANDVGIAWPPGRGPVVLSVLTTK +HVSTAPADEPLVAEAAALLA--- +>[subseq from] D-alanyl-D-alanine carboxypeptidase family protein n=1 Tax=Hydrogenophaga sp. RAC07 TaxID=1842537 RepID=A0A1B3M2Q7_9BURK +---WQARLQQLEATAQGRLGVAILDTATGQVH-GHRADERFMMLSSFKLLASALVLARVD +RGQESLDRRITFAKTDLVTYSPVTERFAGTTMSLAGLCEATLTTSDNSAANFILDSFGGP +AALTRFARALGDDTTRLDRRETELNTGTAAALLDTTTPRAMALTMQKLLLGNALSPASRQ +LLQQWLVGNTTGDKRLRAGLPSGWRVGDKTGTNRT-DANDIGIAWPANGPPLIITSYLAE +STASSAVKEATLAGVARLA---- +>[subseq from] class A beta-lactamase n=1 Tax=Compostimonas suwonensis TaxID=1048394 RepID=UPI000C23C065 +----PTAFAQLEDEYDVRLGVSGIDIGTGAIV-SYRADERFAYASTSKALLAGAILSEAS +--EPELDEVIRYTDDELVGHSPVTEEHIDTGMPLRDVLAAALQYSDNTAANLMFGRLGGP +GGLGDRLRAIGDSTTHVDRVEPELNEAVPGDIRDTSTPAALAADLRELAFGSALAPERRG +LLTDWLRGSTTGADLIRAGVPDDWAVGDKSGAGGYGTRNDIAILWPPTGSPIVLAVMSTT +TTEDAEYDDALIAAAARVAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=UPI000767DD11 +-----ARMRELEREYDARLGVFALDTGTGRTV-AHRADELFPVCSVSKTLAVGAVLRDLD +RDGEYLARRVRYTEDDVKTHIPVTGANIANGLTVEELCAAAVSCSDNGAMNLLMRGLGGP +AAVTRFCRSLGDPTTRLDRWEPDLNSAEPGRVTDTTSPRAIGQTYARLAVGRALDAGDRK +RLAGWLVANTTGDARIRAGVPAGWTVGDKTGTGRYGTTNDVGIAWPQDRAPIALAFLSTR +QEQDAKAVDGLIAEATALAV--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium porcinum TaxID=39693 RepID=A0A5E8P5L5_9MYCO +---LDDQIADLERRHNALIGLYASNLDSGRTL-AHRPDEMFAMCSTFKGYAAARVLQMVG +RRQISLDNRVFVDREAIVPNSPITETHVGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAAGYRQVLAGDALSPPQRR +QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS +QADDADNLRPLIGELTAAV---- +>[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas TaxID=40323 RepID=A0A2J0SIN1_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLGTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA +SAISYEQQAVVLAQVGRIA---- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinoplanes atraurantiacus TaxID=1036182 RepID=A0A285KBH1_9ACTN +------RFGELERRFKARLGVYAVDTGNGRTL-AHRADERFAHASTFKALLAAVLLRDLT +--DADLGRVVTYTQANLLEWAPVTSRHVATGMTVEALIDAAVRHSDNTAANLLLREVGGP +AGLQRELRKINDRVTYVSRTEPSLNEATPGDQRDTSTPRALGTDLRRLVLGDDLPPPRRQ +KLAALLRGNTTGGPYIRAGVPAGWTVGDKTGGGGYGTRNDIAVVWPPTGSPLVIAVQSDR +GVRDAASDDALIAEAAKAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2J0U028_STEMA +-----ADFPALEKASGGRLGVTVLDTGSGRRIgGHRQTERFPMCSTFKSMLVAHVLSLAD +AGRLSLDTRVPVAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVTGGP +AALTAFLRDHGDRVTRNDRYEPDMNRFAAGDPRDTTSPAAMAASLARFAVGDGLSAASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG +ASVDEEQRAAVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Hypericibacter terrae TaxID=2602015 RepID=A0A5J6MDI9_9PROT +---AEPDFKAIRARIGGSLGVHALDTQTGRRI-GYDDSSLFAMASTFKLPLAAAVLLQVD +RGQLDLDQAIPIHASDLVNYAPVTSTHLAQGITVRELLAAIIEVSDNTAANLLLDLIGGP +QGFTQFVRDLGDRVTRLDRFEPELNTNLSADLRDTTTARAMVDDMAGFLTGPVLSDASRT +LLIGWLVSSRTGLARIRAGLPSDWKAGDKSGSGANGAINDVAIAWPPGRKPILIAIYLSG +SSHTPDSLSAAHAEIATAIAREf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ADI96-15 TaxID=1522761 RepID=A0A3N6E8A1_9ACTN +--DAERRLARLERASGARLGVYAYDTGSGRAV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP +TAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLALGDALNPRHRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLTAK +TGEDAVRDDGLVADAARVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea septica TaxID=472695 RepID=UPI000BB5441A +-----AVAQQEEQALKARIGIAVIDTGAESVA-SYRGNERFPLNSTHKALLCGALLSAQD +QGKLRLTERTQFDRAALVTYSPVTEKFVAPAMSWGQLCEAAIGYSDNTAANLLAKKLGGP +EAVTRFFADLGDKATRLDRFEPELNSAVPGDMRDTTTPLAVSETLQKLTLGTALTPASRA +QLLQWMRDDKVANALLRSVLPAGWSIADKTGAGEYGSRSIISVVSPENGKPLIIAIYITQ +TEATLAQSNAAIARIGKTIF--- +>[subseq from] Class A beta-lactamase n=1 Tax=Amycolatopsis sp. SID8362 TaxID=2690346 RepID=A0A6B2DVD3_9PSEU +----QPDFAPLERDFDARLGVYAIDTGSGREI-AHRADERFGYASTHKAFSTAAVLQRTS +--MAGLAKVLPYTSADVQPNSPVGEKHAGTGLSLRDAIDAALRYSDNTAANLLFRELGGP +AGLAAALRGIGDTTTHVDRIEPGLNDLAPGDVRDTSTPRAMAADLRAFALGTALPAEQRT +FYTDTMRANRTGDALIRAGTPAGWTVADKTGTGAYATRNDIAVVWPPGRAPIVLVVLSDR +KTADADHDDRLIAQAAKLTLDTy +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces mirabilis TaxID=68239 RepID=UPI0014289DD0 +--DVTARLRALEERYDARLGVFAHRPSTGRSV-RYRADERFPMCSLFKTLAAAAVLRDLD +RHGEVLARRIHYTEDDLVMGSDQTKAHLAEGMTIAGLAEVAITHSDNTAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWEPELNTAEPWRLTDTTSPYAVGRTYGRLVLGDALNRRDRE +LLTHWLLSNTTSVNRFHAGLPKTWAIADKTGSGSYGTANDVGVTWTDNGDPIVLSVLSTM +PAPDAVRDDALVADAAAVIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. S69 TaxID=1641856 RepID=UPI00131C93A9 +------ALTAYERETGGRIGVYAENLVTGARI-AWRAEERFVMCSSFKASLAAFVLARVD +RGEDHLEQMVAYGPQDLLEYAPAAKQNLAKGMSVAEMCQAAVELSDNTCANLLLARVGGP +SALTAFWRSTGDSVTRLDHNEPELNRSPPGDPNDTTTPTAMVGNLRLFLLGEVLSQPSRE +RLTDWMLNCKTGNNRLRAGLPKDWRIGDKTGNNGKDASGDIAVVWPRPDRPVLIAAYTQG +GSPSAAQLEAVFSEIGRTV---- +>[subseq from] Beta-lactamase n=1 Tax=Niveispirillum lacus TaxID=1981099 RepID=A0A255Z271_9PROT +--DISSAIGKLERVRGGRLGVAMLDMQTGAAA-QWRGNERFALCSTFKFLLAAFILSRVD +AGVEQLDRKVLFDKHELVSWSPLTEPHVGQGLRIDALCEAIMIQSDNTGANVLMRESGGP +AALTAFLRQIGDRVTRIDRIEPDMNLVPTGEERDTTTPLSMLSLLRTLLMGSVLNPDSRQ +RLTDWMIDNRTGDTRLRAGLPRGWRIGDKTGSYG-AMNNDIAILWPPAGGPLLLTSYYQN +DTANAQERSAAHADLAALVARRy +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNT372 TaxID=1169154 RepID=UPI0003A46166 +-kTTERRFRALEKEFDARLGVHAVDTGTGREV-AHGADRRFAYASTFKALLAGAVLRAYG +--MDGIDKVVTYTEADIVEYSPVTEDFTDTGMSLRELCAATLWYSDNTAANVLLRELGGP +DALEKVLEELGDDVTEMDRIEPDLSEGKPGDVRDTSTPRALTAGLRAFLLGDALERRERE +LLRTWMATNTTGETLIAAGLPRDWTVADKSGTAGYGGRNDIAVVWPDDGNPILFTVLSSR +DEKDAERRDALIARAATVALE-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. G22 TaxID=1839752 RepID=A0A160ULU4_9BRAD +------ELESYERETGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARAD +RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVVGEALSPASRT +QLTEWIVGCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPKPDVPILIAAYTQG +GRPNAAQIEAVFARVGRMVAE-- +>[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=UPI0007BEE903 +--TFQQSLAKLEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVQEYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRGLGDTVTRRDRYEPELNRPHPSEPQDTTTPRAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingosinithalassobacter portus TaxID=2676234 RepID=UPI000D6E5A41 +-------FDDLARKFYGGIGLSALDTGSGRRI-DFDAISRYAMCSTFKLPLAGMVLALND +AGKLRLDERIGFGPDDLVPYAPFIERQMDRGATLAELCQAAVTVSDNVAANLLLRRIGGP +QAFTQWLRGVGDTTTRLDRIEPDLNSNLPGDSRDTTTPGAMLDTVNRLVLGDALTPASRG +QLAQWMVACETGDNRLRAGVPSEWRVGDKTGTSTNGASNDVAIIWPPERAPILIACFINC +DTVTARDRDAAHAKVADRILTEf +>[subseq from] Beta-lactamase n=1 Tax=Rubellimicrobium roseum TaxID=687525 RepID=A0A5C4NBJ2_9RHOB +---LDTAMADLEARSRGRLGVAILESGSGMTY-AWRGMERFRMASTFKALLAGAVLRRVD +QGQESLAREVEVRPEDLVEYAPVVEPMVGQSLTVGALCEGTVTLSDNAAANLLLDSMGGP +EGFTAILREIGDEVTRLDRREPDLNTGTPDDPRDTSTPLAYLATLQRMLLGNALSTAGRE +QLLAWLVANKTGDDRIRAGVPEGWTVGDKTGTSGQGDIHDIAVLVPPKGVPILVVAFLSE +TDQPIEEMNGIHAEIGALAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CB02009 TaxID=1703938 RepID=UPI000B059C68 +--DLLARLRELEERHSARLGVFAHDVRSGRSV-AYRADEHFPMCSVFKTFAVAAVLRDLD +RDGSFLARRIRYTAADVERWSPKTEENLAHGMTVAELCDATLRFSDNTAANLLLRELGGP +TAVTRFARSIGDRTTRLDRWEPELNSAEPWRRTDTTTPRAAGRSYGRLLLGDALPVEDRE +RLTAWMLGNTTSGERFRKGLPADWILADKTGGGRYGGNNDAGVTWPPDGGPIVLTVLTTR +FVEDAAPVDPLVADAAALVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces mirabilis TaxID=68239 RepID=UPI00099BEF2E +--DVTARLRALEERYDARLGVFAHRPSTGRSV-RYRADERFPMCSLFKTLAAAAVLRDLD +RHGEVLARRIHYTEDDLVMGSDQTKAHLAEGMTIAGLAEVAITHSDNTAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWEPELNTAEPWRLTDTTSPYAVGRTYGRLVLGDALNRRDRE +LLTHWLLSNTTSVNRFHAGLPKTWAIADKTGSGSYGTANDVGVTWTDNGDPIVLSVLSTM +PAPDAVRDDALVADAAAVIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium guangzhouense TaxID=1325095 RepID=UPI001009C98F +------ELESYERESGGKIGVYAENLATGAQL-AWRADERFVMCSTFKASLAACVLTRVD +RGEDKLAAMIPYGKADLLDYAPVAKQNLSAGMSVADICKAAVELSDNTCANLLLARIGGP +AALTTFWRSIGDTISRLDHIEPELNRSPPGDVRDTTTPAAMAGNLKRLVAGEALSPASRA +QLTEWMVGCKTGANRLRGGLPKAWKIGDKTGNNGKDASGDIAVAWPKLDAPILIAAYTQG +GTPNPTQLEAVFASIGRRVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces fragilis TaxID=67301 RepID=UPI000D5964C9 +---AATRLDALERQHGARIGVFARNLRTGATV-RHRSDERFPVLSVFKTLAAAAVLRDRD +TDGTFLDRRIHYTEAQLVENSDVCRANLATGMTIRELCAAAVQWSDNTAGNLLLRQIGGP +HGITRFARSLGDPVTRLDRWEPELNSGEPWRRTDTTAPAAIAATYARLVLGDGLGRGDRE +QLTSWLLGNRTGDRRLRAGLPPQWTVADKTGAAGYASLNDVAVVWTEDGTPLVMAVLTTK +PERDAVRQDVLLEETARVLAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium canariense TaxID=255045 RepID=UPI000A1946E7 +--DAQPELETYERESGGRIGVYAENLATGARL-AWRADERFVMCSTFKASLAACVLARVD +RGEDQLAAMIPYGKADLLEYAPVAKQNIAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTASRLDHNEPELNRPPLGDPRDTTTPAAMAGNLRRLLTGEALSATSRA +QLTEWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKDTAPILIATYTQG +GTPSAAQIEAVFARIGRIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sacchari TaxID=115433 RepID=A0A1I3Q359_9PSEU +--TAAPDFHDLETRFGARLGVYALDTGSGKEI-AYHAEDRFAYASTIKALAVGALLLQGA +----DLDKRLTYTQADIVSHSPVTGPRVNTGVTVREAAEAALQQSDNTAGNLLFRELGGP +AGLANALRSIGDTTTHPDRWETSLNEAAPGDIRDTSTPRALATSLRAFALGDALPADKRD +LLVDLMRHNTTGSGLIAAGLPEGWTSADKTGSAGYGTRNDIAVVWPPSSAPVVLAVLSTR +DTKDATYDDKLIAEATARAV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=D2CGR9_STEMA +-----GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPETNSFAEGDPRDTTTPAAMAGSLQRVVLGKALQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium asiaticum TaxID=1790 RepID=A0A1A3N0K7_MYCAS +--DLSRRFGDLERRYGGRVGVYVPETATTTAL-AYRADERFAFCSTFKAPLVAAVLHQYP +--LAHLDTLVTYTRSDINSTSPVTEQHVGSGMTVRQLCDAAIRHSDGTAANLLLSQIGGP +AGFTGYLRGLGDGVSRLDQAEPELNRDAPTDDRDTTTPRAMASVFQQLVLGDALPADKRT +LLVDWMMRNTTGDNRIRAAFP-DWKVADKTGSGDYGRTNDVAVAWSPGGVPHVIAIYSDC +TAYDAQPDEAVVADAARIVVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinobacteria bacterium OV320 TaxID=1592329 RepID=UPI0009EBA829 +---VTERLRDLEAGHGARLGVFAYNVRTGRSV-RYRAAERFPVCSLFKTLAVAAVLRDLP +--EGTLDRRVFWTSTDVVENSPVTQDHVADGMTIAELSAAAIQRSDNTAGNLLLRELGGP +TAITRFARSVGDRVTRLDRWEPDLNSAEPDRVTDTTTPYAIGRTYARLVLGDALAPADRR +RLTDWMLGTITSANRFRAGLPPTWTIADKTGGGWYGANNDAGIAWTPDGAPVVLAVQLTK +PDREAAYDNELIVKTAEVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2J0ULS1_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDALSRSDRLEPELNSFAKDDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLIAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0005B8D3FE +-----GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDLRDTTTPAAMAGSLQRVVLGKVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces glaucescens TaxID=1907 RepID=A0A089X3A0_STRGA +----TGRLRALEREYGAKLGVYAHNVGTGRTI-RHHADDLFPICSLFKTLAAAAVLRDLD +RDGEFLARRIHYTEADLVDGSDETRKHLAEGMTVAELCDVTIRYSDNAAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYARLVLGDALPGADRE +LLGHWLLNNTTSSDRLRAGVPPTWTVADKTGGGDYGVNNNVGVAWTPDGTPVVLAVLSRM +FDPAAVRDNTLIARTAKVLTD-- +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Methyloumidiphilus alinensis TaxID=2202197 RepID=A0A2W4T6X0_9GAMM +---VKARLRTLEAAAHGRLGVHILDTSTGQEY-GYRSDERFMLLSTFKLLASAFVLHRVD +AGQESIVRRISYTQADLIAWSPITEKHADGSMTLSELCEAAVTASDNTAANLILSSYGGA +PALTAFMRRLGDGVTRLDRKEPELNFKGANGLWDTTSPRAMVYTLKKVVLGNELSSTSRD +QLQQWLLNNTTGGRRLKAGLPASWRIGEKTGTNRK-GANDIGVIWPPNRAPIVVAAYLND +SLASAEIKESTLAAVGKLVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Dyella ginsengisoli TaxID=363848 RepID=UPI00036E824D +-----DAFAALEKGHGGRLGVAVLDTGSGKRL-LHRADERFLLCSTGKLLAVAAVLARVD +RGEERLDRRIVFRREDVLDWAPVTRLRPGPPMTIEELCQAAMIVSDNTAMNLLLASLGGP +ATLTRFVHGLGDPLTRFDRTEPSLNRPGPGGFEDTTTPLAMLDDMRRVLLGDVLSPASRE +RLLDWLRHNTTGTTQLRAGLPAGWTAGDKTGASQT-QNNDVAIVWPPGRAPVLIAAYYES +SAGAGDARKSVLAQVGALAA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000810D999 +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDALSRSDRLEPELNSFAKDDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLIAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces bauhiniae TaxID=2340725 RepID=UPI0013BF9A2E +--ALRPELAALEKRYGARLGVYAHNTRTGTTV-AYRADEPFAMCSTFKAIAAAAVLRDFG +-GRAALGEVIHYPPADILSSSEHTKARQETGMALGDVCAAAIQYSDNTAGNLMLRRIGGP +AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPRALGRTFELLTLGRALSQGDRE +QLVGWLRGNTTSTHRFGAGLPSGWVLADKTGTGSYATANDLGVAWTGRGTPLLLSVLSTK +PEPDAPVDEALIEETARLLA--- +>[subseq from] Beta-lactamase n=2 Tax=Mycobacterium sp. E802 TaxID=1834152 RepID=A0A1A2LBI4_9MYCO +---VDDQIAELERRHNLLVGLYAENLDTRRRV-THRPDDMFAMCSTFKAYAVARVLQLVE +HGQLSLDHRVFVDPQAIVSNSPVTETHAGAEMTMGELCQAALQRSDNTAANLLLKAIGGP +AAVTEFARSVGDQRTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILTGDALSPRQRR +QLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAYGPDGQRILLVMLTRS +QADDAENQRAVIGELTALV---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. FIRDI 009 TaxID=714197 RepID=UPI000E2559F0 +----DAEFTRLEEEFGARLGVHALDTGTGQAV-EFRADERFAHCSTYKVLAFGAVLDRTP +--VDELDRVVTFSGADLVFHSPVARERVSTGMTLRELGDAALRHSDNTAANLLLAELGGP +EGLTEALRGIGDDVTRVDRFAPEMAQAVPGDDRDTSTPRAMAASLRAFALGEVLPEDRRA +VLVDMMRSNTTGDDLIRAGAPEGWAVGDKTGACGYGTRHDIGVLWPPEGDPVVLAVMSSR +DEAGAGYDDALVARATEVAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Actinoalloteichus hymeniacidonis TaxID=340345 RepID=UPI0008536456 +--AVEAELAALEAEFGGRLGVYAVDTGSGNSI-GHRAQERFLLCSTAKVLAVAAVLRLRV +TEPELMERVVQYDQSQVLEYAPVTAQHVADGMTVSALCDAAITVSDNTAMNLLMELVGGP +DGVTDFCRSLGDEHTRVDRMEPELNVGAPGDERDTSTPEQMAVDLRELALGAGLDETGRE +LLVGWLRANTTGDEQIRAGLPADWQVGDKTGSGSLGEINDIAVVWPPEADPWVIAVYTAP +DDPESTTGRATVAAATAIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodobiaceae bacterium TaxID=2026785 RepID=A0A2E5BUS5_9RHIZ +--TLLETVRKIEHRSNGQLGIAIHDTGLDRHW-YYKADERFPLSSTFKPFACAGLLSKMD +KGEEHLDRRLIVHSEDIVTYSPVTANHIGPPLSLSQLCEATITLSDNTAGNFVLKALGGP +TGFTAYMQSIGDKTTRLDRWETALNEAHPGDAQDTTTPRAAMTSLTTLLLGEALSPASRD +RLTGWMRNDKVADALLRASLPQNWEIADKTGAGNNGSRGIIAVIWPPAQAPLIVAIYMTG +TSFSLEERNTAIAEIGHALVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0007659290 +---LSRQLAELEREYAARLGVYAHDTATGRTV-AHRADERFPICSVFKTLAAGAVLRDLD +RDGEYLAKRIHYTKEYAEAYSPITATNVEAGMTVGELCSATVSHSDNGAGNLLLRELGGP +SAITRFCRSLGDRTTRLDRWEPQLNTAEPWRTTDTTTPRAIGRTYARLLLGRALRDADRE +LLTDWLIANSTNVQRFRAGLPADWTLADKTGGGTYGVANDVGVVWPPGRPPLVLSVLSTK +HDPAGPTDNPLVARAAGLVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID10853 TaxID=2706028 RepID=A0A6B2RRU3_9ACTN +---AAPALKKLEHRYGARLGVYALDTGSGRTI-GYRADERFAYASTYKAPAAAVLLRTAS +--DADLDHVITYRAADLQDYSPVTRPHLSTGMTLRALINAALRYSDNTAANLLLDRIGGP +KALQRALRGLGDTTTHVDRPEPDVNTAVPGDVRDTSTPRALGTDLRGFALGGLLPAKRRD +ELNTMLLHNTTGGPYIRAGAPAGWKVGDKTGNGGYGTRNDIAVLRPPHGSPVVLAVLSDR +GRQNATSDDALIADATKATL--- +>[subseq from] Beta-lactamase n=1 Tax=Actinoalloteichus hymeniacidonis TaxID=340345 RepID=A0A1D8BXR9_9PSEU +--AVEAELAALEAEFGGRLGVYAVDTGSGNSI-GHRAQERFLLCSTAKVLAVAAVLRLRV +TEPELMERVVQYDQSQVLEYAPVTAQHVADGMTVSALCDAAITVSDNTAMNLLMELVGGP +DGVTDFCRSLGDEHTRVDRMEPELNVGAPGDERDTSTPEQMAVDLRELALGAGLDETGRE +LLVGWLRANTTGDEQIRAGLPADWQVGDKTGSGSLGEINDIAVVWPPEADPWVIAVYTAP +DDPESTTGRATVAAATAIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis sp. AC460 TaxID=1282360 RepID=V4NZK0_9CAUL +----AAAMLDITKRHGGRIGVSAIDAGSGGRL-SVSSQERFGMMSVFKWILAAAVLARVD +KGELKLDQVVRFGRKDLVGWSPVTEKKVKDGITVGELCAATVSKSDNAAANLLLPLVGGP +EGLTKWIRSLGDGVTRVDRKEPEMNNVAEGDPRDTTTPEAMTQLLQIVFTGAALEAASIK +QLREWMVATSTGDKRIRAGVPSGWTVADKTGTAN-GAVNDVAVIWPKSEGPIFLSIFTVG +GTLEPEAKEQVVADIARLVCDVf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. AW19M42 TaxID=1379686 RepID=UPI000463E07F +--RTAQAFRDLERKFDARLGVHTLDTGSGRTV-THRPDERFAYASTCKALLVGAVLDKNS +--LRQMDRLVRYGRDDLVSASPVTERHIATGMTLRELSDAAIRYSDNTAANLLFHELGSP +RALQGALRALGDDVTRCDRYETALSDATPGDLRDTSTPRALATGLRAYVLGTTLPADKRA +VLTDLLRRNTTGDNTIRAGVPDHWQVGDKTGTGGYGTRNDIAVIWPPGAAPITLAVLSRR +DAKDAERDDALIAGAAKVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Dyella soli TaxID=522319 RepID=A0A4R0Z0S3_9GAMM +----QDKFADLERRFGGRLGVAIHDLETGQKA-GHRQDERFLMCSTFKLLEAAAILARVD +KGAESLDRRIVFGPDVLLSHAPITRQHAGGEMTVGELCQAAITVSDNTAANLLLESLGGL +MAFNGFLRSLGDHVTRLDRNEPTLNVA--HGDLDTTSPKAMLGSVEKVMLGDALSPASRE +QLAAWMKQTTTGLTAIRAGLPPAWLAGDKTGRGSHGETNDITLAWPPGRKPVLIVAYYAH +PDVSDDVRSHVLAEIGRMVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. CCH5-F6 TaxID=1768753 RepID=UPI00076A41E6 +------EFAAYERESGGRIGVHAENLATGAKL-AWRADDRFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGQADLLEYAPVARQNLAASMSVGEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSRPGDSRDTTTPAAMAGNLRRLVLGEALSPASRV +QLTEWMVNCRTGANRLRGGLPADWKIGDKTGYNGKDAAGDIAVAWPKPDTPILITAYVQG +GTPTAAQIASVFAQTGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. XY511 TaxID=1519480 RepID=UPI0006B00568 +----VRRLRALEAEYGARVGAYARDTGTGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD +RDGEFLARRIHYTQGDVTAGGSVTERNIAGGLTVSELCSAAIAQSDNCAANLLLRELGGP +TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE +LLTRWLVSNTTSDERFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK +PDAAAPRENALVARAAEVLA--- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio sp. PID17_43 TaxID=1583451 RepID=UPI000BFFEAA1 +--QLNEDLAAIEQHIAGRIGVTVWDTQTDQRW-DYRGDERFPMMSTFKTLACATMLNDMD +SGKLDKNATAKVEERDIVVWSPVMDRMTGQTTRVEHVCEAAMLMSDNTAANIVLRSVGGP +RAVTLFLRSIGDKATRLDRYEPGLNEATPGDKQDTTTPNAMVNTLHTLLEGEALSYESRT +QLKIWMQDNKVSDSLMRSVLPKDWSIADRSGAGGFGSRGITAMIWKENHKPVFISIYITE +TDLSLQARDQVIAKISQLVLEEy +>[subseq from] Beta-lactamase n=1 Tax=Kitasatospora sp. MMS16-BH015 TaxID=2018025 RepID=A0A2H5BA97_9ACTN +--DLDHRLSALEQRHSARLGVFAQDTGTGRTV-RYRAEELFPFCSTFKTIAVAAVLRDLD +RDGTYLAKVIRYSEQEVKAYAPITGQNLANGMAVADLCAAAIRYSDNCAANLLLRELGGP +TAVTRFCRSVGDRTTRLDRWEPALNSAEPGRVTDTSSPAALGRTYARLTLGDALDAPDRA +RLTDWLKGNTTSTHRFRAGLPESWTLADKTGTGDYGTTNDAGLTWPPGRAPIVLTVLATK +QDQAAPADEPLIAATAALLAE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6ALC7_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVXLLGPNNKA---------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonadales bacterium 14-68-21 TaxID=1970612 RepID=A0A259R2T8_9GAMM +--DAADAFAALERRHGGRLGVAVLDTGSGRRL-LHRADERFLMCSTGKLLAVAAVLARVD +RGEERLDRRITFRPDDVLEWAPVTRLRVGPPMTVAELCHAAITVSDNTAMNLLLASLGGP +ARLTRFVRGLGDPLTRFDRTEPSLNVPGPQGIEDSTTPVAMLDDMHRVLLGDVLSPVSRE +QLLDWLRHNTTGTQQLRAGLPAGWTAGDKTGASQT-QNNDVAIAWPPGRAPVLITAFYEG +PAGATEARKAVLARVGTLA---- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea maritima TaxID=683260 RepID=A0A1G9FV38_9ACTN +-eRVKKELRDLERQLGVRIGAYVIDGGTGQAL-AYRSGERFPLTSTFKAVAAAAVLHKAR +TDPGLMDRVVKWSAAEVKPNSPITEQHVKDGMTIAQLCHAAITRSDNTAGNMLLKQIGGP +AGLTRYFRTLKDPVSRLDRWETDLNSWSPKERRDTTTPAAIARDLRQLTAGDALSAKDRE +RLNGWLKANTTGGARIRAGLPASWTVGDKTGTGGYGTANDIAVAWPRKGAPVIMAIYTNG +RTADAATQDKAVADAARILA--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000C06B10F +----EQAFGGLERKFDARVGVYAVDTGSGVTV-THRPDERFAYASTCKALMAGALLKTRP +--LPQLDRRVRYGPDDLVANSPVAERHVDTGLTLRELCEAAVRYSDNAAANLLFHELGGP +RGLRDALVALGDRTTRCDRIEPDLSEAAPGDVRDTSTPRALASDLRAYTLGGALGTDARA +VLNDWLERNTTGDALIRAGAPAGWVVGDKTGTGGYGTRNDIAVVRPPGSAPIVLAVLSRR +DTRGAEPQDALVAEAARVALDAf +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. SGAir0471 TaxID=2070337 RepID=A0A4P8SWY1_9MICO +--ATSRAFAALEEQYGARVGVVAINTADGSSL-GYRADERFAFASTNKAFIAAAVLDASS +--ADDLDDVVHYDRSDLLSYAPVTSLHVDEGMTVRALVDAALRQSDNTAANLLVERLGGV +GGVSRFLRGIGDDVTRVDRVEPDLNTAVPGDPRDTTTPAQSATDLRAVLLGDALDPDDRA +LLRSAMAGTTTGDGTIRAGVPDGWSVADKTGTASYGVRNDIAVVEPPGRDPIVLVVFTTR +DGADDESSDALVAAATRVAVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. KBS0715 TaxID=1179671 RepID=A0A554N666_9MICO +--ATARAFAALERRYDARLGVVAVDTGDGRTI-AHRAGERFAFASTVKVFIAAAVLGASS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTRVDRVEPDLNEATPGDRRDTTTPERFAADLGTVLLGDALDATDRR +VLREAMLGNTTGDATIRAGVDPSWQVADKTGTASSGVRNDIAIVTPPGRAPIVLVVMTSR +ADPGAEPSDALVAAATRVAV--- +>[subseq from] Beta-lactamase n=1 Tax=Actinoallomurus bryophytorum TaxID=1490222 RepID=A0A543CC21_9ACTN +------ALARIEHRYHARLGVYAVDTGTGRTV-AYRADERFAYASTFKALAAGILLEHTT +--ARRLDQVVRYRESDLLEYAPITSEHVRTGMRVRDLIAAALRYSDNTAANLVMARIGGP +HAVQAGLRRLGDTTTHVDRTEPSLNEATPGDIRDTSTPRALGTDLRRFVLGDVLPVSRRK +PLTGWLVTNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRDDIAIAWPPGGAPVVIAVQSDR +GVKDAPSDDALIADATKAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DED861 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--PTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DAC6CB +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGDDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Xenorhabdus nematophila TaxID=628 RepID=UPI000DE94490 +----------LEKNANGHLGAVLINTADHSTI-AYRADQRFPLCSTSKLMAVSALLKRSE +TNDHLLNQQAHYQQSDLVEYSPITEKHLKSGMTLGELSAATLQYSDNAAMNLILNQLGGP +HEVTKFARTLGDNSFRLDRKEPELNNVIPGDERDTSTPRAMADDLYHLVLGNALDATQRE +QLITWLKGNTTGAASIRAGVPEGWIVGDKTGRCDYGSTNDIAVIWPVNQPPLILVTYFTQ +PDKEASARPDVLAAAARIMTQH- +>[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2Y9UA04_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAMTLQRVGMGEVLKPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Agreia pratensis TaxID=150121 RepID=A0A1X7JDE5_9MICO +------AFAELEQEFDARLGVYALDPDSRAEV-AYRADERFAYASTFKALAVGILLKTVP +--DDQLDQLVTYDASELLPNSPVTEANVDSGMTLRAVAEAAVRFSDNTAGNIVLEKLGGP +EGFTQALRELGDTTTSSDRIETDLNSAIPGDTRDTTTPRAFALDLATLLTTDALGAAQQA +QLIDWMTGNATGAELIAAGLDAGWSVADKSGAGAYGTRNDIALLWPPSGSPIVLVVMSNR +PAEDADYDNALIARAAEAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_021 TaxID=2175639 RepID=A0A2W1W7A8_9MICO +--ATARAFAALERRYDARLGIAAVDTGSGRTI-VHRAGERFAFASTVKVFIAAAVLDASS +--DADLAIVVHYDRGDLLEYAPVTREHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP +NAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSR +ADPGAEPSDALVAAATRAAV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SA78_KLEPN +----------------GRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVISC-- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Paracoccus hibiscisoli TaxID=2023261 RepID=A0A4U0QTB5_9RHOB +--TIAQAARAIETELGGRVGVALRRQGDAQVT-GYRPDERFPLSSTFKAPLCGAILTLVD +AGADQLDRPIGYTSADLVEYSPVTSTHD--AMTVGALCEATITLSDNTAANLLLDRLGGP +EDFTAYLRAIGDDTTRLDRRETALNEAAPGDPRDSSTPAAMTATLDRLLFGPILSAASRD +QLEAWMRADQVADDLLRASLPQGWIIGDKTGAGGFGSRSIVAVIRPPQGAPWLAAVYLTG +NEADMPTRNRAIARIGAAIVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID12488 TaxID=2706040 RepID=UPI0013D94CEE +--DVTARLHALETQHGASVGVFAHNLGTRKTI-RHRADERFPVCSLFKTLAAAAVLRDLD +RVGEVLSKRVHYTTDDLVDGSKQTEEHLAEGMTVAELADAAIRFSDNTAGNLLLRELGGP +GAITRFARSLGDRATRLDRWETELNSAEPWRITDTTTPYAIGRTYARLVLGDALNRPDRE +LLTHWLLNNTTSGNRFRLTLPPTWTIADKTGAGSYGTNNNVGIAWTQDGTPIILAVQTTK +PDRDAAADHPLVAETARVL---- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_034 TaxID=2175623 RepID=UPI000DA8AB84 +--ATARAFAALERRSDARLGVAAIDTGSGRKI-AHRAGERFAFASTIKVFIAAAVLGASS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAAGRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR +ADPGAEPSDELVAAATRTAV--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000709EADE +----ATDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVRDVDLLSHAPVTRRHAGKNMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA +GAISYEQQAVVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora echinaurantiaca TaxID=47857 RepID=A0A1C5HDF0_9ACTN +----HHRLTELERRYDARLGVYALATGTGTTI-AHRADERFAFCSTFKGLAAAAVLHANP +--LSHLDTVVRYTEHDLMKSSAITRRHVATGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP +ARLTAYLRGLGDPVTRMDRIEPDIVTAIPGDPRDTTSPRAIGADYQQIVLGDALPPDKRA +FLRGLLERNATGARRVRAGVPKGWTVADKTGTGDYGTLNDIALVWPPGSAPLVISIMSSK +ATRDAAYDQALIAEAAAYVVA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Methylobacterium sp. WL119 TaxID=2603888 RepID=A0A5C8VVV4_9RHIZ +---ATDTLREIERRVGGRLGVSVGRSNGPPLL-GHRADERFPMCSTFKVLAAAALMARVD +AGTESLDRTLPYGEGDLLKYAPVTRKALEAAISVADACAAAVEWSDNTAANLMLNALGGP +SALTGWLRGIGDRTTRLDRTEPDLNTAIPDDPRDTTTPDAMRTTLERVLVGTVLSPATRT +RLDGWMVAGQTGSKRLRAGIPPDWKVGDKTGSGDNGTYNDVAILSPPGQAPILAAVYLTG +STAPVTDVDAAYAEIGRMIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Clostridium senegalense TaxID=1465809 RepID=UPI00028939AF +--QYNSEFSQLENDYDVKLGVYALDTETGKEV-IYRADDRFAYCSTFKVLVAGSVLKQDT +--LEQLNQVIKYNEEDVISYSPITKNNVEEGMTIEEICKAALQFSDNTAANLLLNHIGGV +SGFKLALNQLGDNVTQPVRIEPELNEAIPGDTKDTSTPRQLAIDLQAYTIGNVLTDDKKK +ILIDWMTGNTTGDTLIRAGAPENWVVADKSGTGPYGIRNDIAVVMPPSKKPIIVAILSTH +DTKEAKHDDKLIAQASKIVFDFf +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase AXC-4 n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A5C0PCS7_ALCXX +--AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Mycolicibacterium TaxID=2636767 RepID=UPI0012DC8F20 +---VDDQIAELERRHNARIGLYAVNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMVG +RGQQSLDHRVFVDPEAIVPNSPVTETHAGAEMTLAELCQAALQRSDNTAANLLLKTIDGP +AGITAFARSVGDQRTRLDRWEVELNSAIPGDPRDTSTPAALAIGYRAVLAGDALSPPQRR +QLEDWMRANQT--SSMRAGLPDGWTTADKTGSGDYGSTNDAGIAYGPDGQRLLLVMMTRS +QA-DDPKADNL------------ +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium amphicarpaeae TaxID=1404768 RepID=A0A2U8Q1M2_9BRAD +-----AELETYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEKLAATIAYGKADLLEYAPVARQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALTPASRG +LLTEWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVAWPRNKTPILITAYTQG +GTPNAAQIEAAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Terriglobus roseus TaxID=392734 RepID=A0A1H4Q4P2_9BACT +--TLPAAIAAMEKKQGGRIGVSVLDTATRERA-AYRADERFPMCSTFKFLLAAAVLHRVD +TLTDDLRRQVDVPPKPLLGNSPLTEEHAGTSMTLGALCSAILTRSDNTAANVLLETIGGP +NAITTYAKVIGDSVTRLDRTETSLNESLKGDPRDTTSPNAMVHNLQSLLLGDALEPDSRT +QLTDWMQSSTTGLIRLRAKLPKDWRAADRTGSNGEHTTNNIAVLWPAGGAPILVAAYITQ +CPGPEDKRNAMLAEIGRLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. WMMB499 TaxID=2650775 RepID=A0A5J6UCP6_9ACTN +--AVSRELARLEAKRNLHIGAYAIDTGTGRFV-SHRADRRFPFTSTFKVMACGAVLKKAR +TDPGLMERVIRYTEDDLVDYSPETEKHVGTGMTVSALCDAAITLSDNTAGNLVMEQIGGP +AGLTRFFRSLGDGASRSDRWETALNEWKPGEKRDTTVPRTWAANLRALTVGDALAPADRD +RLIAWMKANTTGDKRIRDGLPDSWTIGDKTGTGGYGNANDIAIAWPDDGAPLVMVVLTTG +KRKDAGADDAAVAETAAILA--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A3S0JN13_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RAPALLDTRVPVRAADLLSHAPVTRRHAGKDLTVRDLCRATLITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGSPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=M4Q8X9_9BACT +------EVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGK----------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00045B87CC +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTRDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase n=1 Tax=Photorhabdus luminescens TaxID=29488 RepID=A0A1G5PQH1_PHOLU +--RLATVVKQEEQTLNARIGVAVIDTASDKMV-SYRGNERFPLNSTFKALLCGVLLSEVD +KGKVALTDAIQFDKTELVEYSPVSEKFVVPAMNWQQLCSAAVSYSDNTAANLIAKKVGGP +VAMNLFFSGLGDNVTHLDRYEPELNSAIPGDKRDTTTPVAVSQTLQKLTLGEVLKPSSRQ +QLVEWMRDDKVADALLRSVLPAGWKIADKTGAGDYGSRSIISIVWPKDSSPLIVAIYITQ +TEATIAQSNEAIARIGKIL---- +>[subseq from] class A beta-lactamase n=1 Tax=Pannonibacter phragmitetus TaxID=121719 RepID=UPI000B969CA5 +--QLAETVAKTESRLNARVGVVLHDTGSGWSW-ANRADERFLMNSTIKTPICGAILSAAD +AGTLTLDEELPVLQSDIVSYAPVTEKKVGQSMSLSELCLATIDMSDNTAANLLINRLGGT +EAVTEFFRSTGDTVSRLDRLEPDLNTFKSGDPRDTTSPAAMAATLEKLLLGDVLSPQSRN +QLIEWMSHGGVTGALLRKTAPEGWHIADKSGSGDQ-TRNIIAMITPPDRAPWIAVIFVSD +VKADFATRNGALQDISAAVID-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE0DFE8 +----EAQLAALDSKHPGRICVSILDMASGKRI-EHRAGERILMCSTFKALAAALVLARVD +KGEEKLDRRIRYAKSDLVDGSPATKEDAGETMTIAELCAAAVTLSDNTAGNLLLASFGGP +EAITTFCRSMGDEITRLDRTEPTLNYDTPDDQRDTTTASAMLENLRRLLFTDALTAASRS +QLAAWLITNKTGDARLRAGLPKDWLVGDKTGTNGAGNANDIAVLWPANRAPILVTAYCEI +PEIAAGERNAIIAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDEBCA2 +----EAELAALESRHPGRICVSILDMASGTRI-EHRARERILMCSTFKALAAALVLARID +RGQEKLDRRIRYTKSDLVHGSPATKAHLRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP +KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS +QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRASVIVTAYCEI +PAIAADERNGIVAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. FR26 TaxID=2605987 RepID=UPI00135A20DA +------DFERLEEEFDARLGVYAVDTGTGEEV-SHRPDERFAYASTHKALSAGAVLRRNS +--LEEMEEVVTYTEDDLVSHSPVTERHVETGMTLMEVADAAVRYSDNTAANLLMEELGGP +DGFEEALEAIGDDVTDPERMETELNEGVPGDTRDTSTPRAMATSLREFALGDVLPEDRRD +VFTTMLRGNTTGDTLVRAVVPEGWEVGDRTGAGGYGTRNVIAVVWPPEADPLVIAIMSSR +DREDAEYDDALVAGAAEVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces tirandamycinicus TaxID=2174846 RepID=A0A2S1SY88_9ACTN +----VREFAELEDRFEARLGVYAVDTGTGREV-AHNEDERFAYASTFKVLAAGAVLREHS +--LSGLDQVITYSADDLVPHSPVTAKRVGTGMSLAELCDAAVRLGDNTAANLLLDELGGP +RGLDAALEEIGDDVTRMERRETQLNEWSPGSLSDTSTPRALARDLRAYVLEDALGKGERA +QLTEWLRTSATGSELIKAGVPKDWMVGHRAGAGSYGVRNDIAVVWPPDSAPIVMAIMSNG +LRRDADHDDRLIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas taiwanensis TaxID=176598 RepID=UPI001389B1E2 +-----PDFAALEAASGGRPGGCLLGTARGRGQ-GHRLPERFPMCSTFKALLAAAVLAQAD +QGRLSLDRRLQVRARDLLEHAPVTRRHVGKDLTVRDLCRATMVTSDNTAANLLLQAIGGP +AAVTAFVRALGDGVTRLDRYEPELNLHAPGDPRDTSSPAAMAASLARVVAGEALAPASRQ +QLADWLVDNQTGDACLRAGLGPRWRVGDKTGSDGRGIRNDVAVLWPLGGAPQVLAAFLEG +ARVGAAARDAVLAQAARLA---- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium asiaticum TaxID=1790 RepID=A0A1A3P808_MYCAS +--DLNSQFDQLERRYGGRVGVYVPANATTGAI-AYRADERFAFCSTFKAPLVAAVLHQFP +--LAQLDKTITYTKSDINSTSPVTEQHVETGMTVGQLCDAAIRYSDGTAANLLLDQIGGP +SGFTAYLRSLGDNTSRLDQAEPELNRDPPNDERDTTSPHAIALVFQQLVLGDALPADKRA +MLTDWMARNTTGGNRIRAAFATDWKVIDKTGSGDYGRANDVAVVWSPGDVPHVIAIYTDL +VAYDAEPNEAFVADAARIVAS-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 1-11 TaxID=2590549 RepID=A0A510TGN0_9ACTN +---LGREFGDLERRYGARLGVYARNARTGRTA-AYRAGEPFAMCSTFKAFAAAAVLRDQA +-GCAPLDKVIHYPARDILDNSQYSYDHLATGMTVGEACAAAIQYSDNTAGNLLLRQIGGP +QGLTRFFRSLGDRVSRLDRWETELNTAVPGDPRDTSTPRALGESFERLTLGRALARADRE +QLVTWLKGNTTSGQRFGAGLPAGWVLADKTGTGSYATANDIGVAWTTRQTPVLLTVLSTK +DAEDAPVDNELIRRAAEVLA--- +>[subseq from] Beta-lactamase Axc n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A3G1JAD7_ALCXX +--AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium tropici TaxID=398 RepID=A0A329Y8Y7_RHITR +----EERLAALESKHPGRICVSILDMASGRRI-EHRAGEHILMCSTFKALAAALVLARVD +KGEEKLDRRIRYSEGDIIGGSPATKLRVGDGMTVAELCAAAVTLSDNAAANLLLASFGGP +KALTAFCRSLGDDLTRLDRTEPTLNYDTPDDQRDTTTAAAMLENLRRLLFTDVLTASSRS +QLAAWLITNKTGDARLRAGVPKDWLVGDKTGTNGAGNANDIAVLWTSKRAPIIVTAYCEI +PSISADERNAVIAEIGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces virginiae TaxID=1961 RepID=A0A0L8M7Q2_STRVG +---VVARLRELEREYGARLGVYARDTATGRTV-AHRADELFPMCSVFKTLAVAAVLRDLD +HDGAHLAKRIHYTLQDVTDGGSVTERNIAGGLTVAQLCSAAIAQSDNLAGNLLLRELGGP +TAVTRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLAIGDALDSGDRE +QLNRWLLSNTTSADRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPVVLSILSTL +PEPTAPRDNTLIARTAKLLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ncost-T10-10d TaxID=1839774 RepID=A0A1C5CZZ2_9ACTN +---AVRKLRDLEREHAARLGVFGWNTVTGRSV-LHRAEERFPMCSTFKTLAVGAVLRDLD +HDGTFLSKIIHYTKQDIKRGAPVTGENLAQGMTVEDLCGAAISYSDNTAANLLMERLCGP +TSVTRFCRSIGDSVTRLDRWEPELNSAEPGRVSDTTSPRAIGKTYAQLVLGNALEAGDRK +KLTGWLLANTTGGKRLRAGLHEDWSVGDKTGTGSYGTANDVGIVWPPGQGPIVMAVLSTK +HDADSEADDLLIAHAAAVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Actinoplanes rectilineatus TaxID=113571 RepID=UPI0005F2B126 +------DLGTVEERYGARLGVYAVDTGTGRVV-THRADERFAHASTFKALQAGVVLRIAS +--DADLDRVVTYRKRDLLAHAPITEKHVATGMTVRDLLDASLRYSDNTAANLLFATIDGP +DGLERELRALGDTTTSVDRIEPDLNEAAPGDTRDTSTARALAADLQSLLLGDALTPDRRR +LLDGWMRANTTGGPYIRAGLPDGWTAADKTGAGGYGTRNDIAVLHPPAGSPIVLAVLSRR +TAENAGSADALIAETTKSVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Actinospica robiniae TaxID=304901 RepID=UPI0012F7F3C5 +-----AAFQQLESRYGARLGVYAIDTGTGRSV-AFQADERFAFCSTIKAFAAGELLRRET +--DAQLAQTITYSASDLVDYSPVTSKHVQGGMTLTAVMSAAIEVSDNTALNLMFGRLGGP +AGLQSALRSLGDATTDVDRTEPTINTAVPGAVQDTSTPRALAADLRAFVLGDVLTAGRRA +RLTAWLQANTTGGPYIRAAVPTGWKVGDKTGNGDYGTRNDIAVLWPTHGAPIVIAVLSHR +GTQNASSDDGLIADATKLALQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=UPI0006E1C018 +---LTGRLRELEEEHSARLGVFAHDIRTGRSV-AYRADERFPMCSVFKTLAAAAVLRDLD +HDGSFLARRIRYTAADVERFSPRTGENLAHGMTVAGLCDATLRYSDNTAANLLLRELGGP +TAVTRFARSIGDGVTRLDRWEPELNSGEPWRDTDTTTPRAIGRTYGRLVLGTALTPRDRD +RLTGWMLANTTSGERFRKGLPADWILADKTGGGRYGGNNDVGVAWPPTGGPVLLAVLTAK +PEEDAEADNPLVAGAAALVAA-- +>[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=M5D2E8_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RRPALLDMRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDALSRSDRLEPELNSFAKDDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIGVLWPVGGAPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Clostridium sporogenes TaxID=1509 RepID=UPI000A16D746 +--QYNSAFSQLESDYDVKLGIYAFDTEMNKEV-VYHADDRFAYCSTFKALAAGAVLKQDS +--LDELKQVVKYKKEDVLSYAPIAKDNVDKGMTIEEICNAAVRFSDNTAANLLFNHIGGP +SGFKLALNQLGDNVTQPARIEPELNEAIPGDIRDTSTPRQLATDLQAYTTGNILTDDKKR +ILIDWMTGNATGNTLIRAGAPDNWVVADKSGTGPYGTRNDIAIVMPPNKKPIIIAILSTH +HTKEAKYDDKLIAQASKIVFDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A1W6AL97_KLEOX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVAXLGPNNKA---------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-241 TaxID=1463896 RepID=UPI0004C12C64 +---VVARLRELEREYGARLGVYARDTATGRTV-VHRADELFPMCSVFKTLAVAAVLRDLD +HDGAHLAKRIHYTLQDVTDGGSVTERNIAGGLTVAQLCSAAIAQSDNLAGNLLLRELGGP +TAVTRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLALGDALDSGDRE +QLNRWLLSNTTSADRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPLVLSILSTL +PEPTAPRDNTLIARTAKLLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. SLBN-2 TaxID=1522278 RepID=A0A543HQD1_9RHIZ +---------GIEAKLGARLGLMVVDTETGRQW-QHRSRERFAMASTFKALACAALLDA-- +-GETVQSRSVTIEKQDLQDYSPVTGQRVGSQMTAAELCATTLRTSDNTAANLVLAALGGP +KRVTSFLRSIGDTVTRLDRTEPMVNEAKPGDPRDTTTPESMTQSIGDLVLGDALSADARR +QLTGWMEANEVADRLLRAGVPQDWRIADRTGAGGHGTRGIVAVMWPPQRKPVIAAIYLTE +TDASLAERDAAIAEIGRAIAA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2B3H8_STRVZ +---LTGRLRELEEEHSARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTLAAAAVLRDLD +HDGSFLAQRIRYTAADVERFSPRTGRNLAGGMTVAGLCDATLRYSDNTAANLLLRELGGP +KAVTRFARSIGDGVTRLDRWEPELNSGEPWRETDITTPRAIGRTYGHLVLGAALTPRDRD +RLTGWMLANTTSGERFRKGLPADWILADKTGGGRYGGNNDVGIAWPPTGGPVLLAVLTAK +PEEDAAADNPLVAKAAALVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00061CAC22 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--RTHLDKLLTYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. SC4 TaxID=1793160 RepID=A0A135H462_9NOCA +---LDATIAALEAQYSTRIGVTAVNPVTGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE +DGSTSLDKTVVIEPGDLVENSPVTAAAVGTPMTLGKIAEAALTQSDNTAGNYLLREIGGP +QAVTDFARVVGDESTRLDRWETELNTAFRDDPRDTTTPNGIAQGFRALLLGDALDTASRD +QLLEWMRASKTSDKRMRAGLPTGWTAADKSGGGGFGTANDAGVAWSPDGAPFVLAILTDS +LTEGAQGNNQAIADTTAAVIE-- +>[subseq from] Beta-lactamase n=1 Tax=Cohaesibacter sp. CAU 1516 TaxID=2576038 RepID=A0A5R8YB63_9RHIZ +-qELGETVAAWETKLDGRIGVILRDTASDWTY-SHRSDERFPMASTFKSLLCGAVLGEVD +AGRESLTNQVTYSKKDLVYWSPITKKHLASGLPVSALCEAAVTMSDNAAANLLLKRVNGP +AGLTGFLRGIGDATTRLDRWEPEMSKGTPKDPRDTTSPRAITTSLHNLLFGGALQPASAA +LLKQWMIDDQVADKLIRPHVPDGWIIGDKTGSGGHGTRAIVAFLQTPKGQTFMAAIYITQ +SKAGKDARNQAISAIGRAMIS-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=A0A655AHQ9_MYCTX +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. BIIR7 TaxID=1904462 RepID=A0A1E7RR31_9GAMM +-----SDFAALEKASGGRLGVTLLNTATGARV-GHRQDERFPMCSTFKFVLSATVLHLAD +KGTLSLDRRLPARQQEMLSHAPVTKRHVGKDLTVRDLCRATMVTSDNPAANLLLGVVGGP +AGVTAFLRAHGDTVTRNDRLEPEMNDFAPGDPRDTTSPAAMAASLQRFVLGDTLSKPARL +QLADWLIDNETGDARLRAGLSPAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG +ASVDDAGRNDVLRQVAVI----- +>[subseq from] class A beta-lactamase n=1 Tax=Luteimonas sp. 100069 TaxID=2006109 RepID=UPI000F5166F8 +--TLDAALAALEQAAGGRLGIALFDTGTGRRL-GRREKERFPMCSTFKALLAGAVLHAVE +RGHVRLDQPVDVAAGDLVPYSPYVETRVAQGARVDDLCRATVTLSDNAAANLLLPLVGGT +SGLTAFLRALGDPVTRLDRWEPDLNEAARDDPRDTTSPRAMVDSLQRLLFGDVLRAPLQA +VLAAWLIENRTGEARIRAGVPAGWIVGDKTGTCGAGTAADVAVLYPPARAPLLLAVYVHG +AGVSGPAIDALQADVARAVL--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=D2CGR7_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATALSQAE +RMPALLDRRVPVGEADLLSHALVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium vulneris TaxID=547163 RepID=A0A1B9CWL2_9MYCO +----DDQIADLERRHNALIGLYASNLDSGRTL-AHRPDEMFAMCSTFKGYAAARVLQMVG +RRQISLDNRVFVDREAIVPNSPITETHVGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAAGYRQVLAGDALSPPQRR +QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS +QADDADNLRPLIGELTAAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. X2025 TaxID=2483796 RepID=UPI000FDBDF24 +----AAELDALEERYAARLGVFAVDTGSGATV-EHRADERFAYASTHKALSAAAVLAGSG +--PDRLDDVVRYDASELVAHSPVTEQHVGTGLPLRRIAEAAVRESDNTAGNLLLEELGGP +AGFERTLEALGDDVTVAARRETALNEATPGDPRDTTTPRAFAQVLRAYAVDDALDTPDRR +TLLRWMRGNATGDTLVEAGLPDGWRVADKSGAGGYGTRNDIAVVHPPGRAPIVVAVFSDR +GRPDADYDDRLVANAARAVV--- +>[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI000DD10E4E +--AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FE0FB8C +-hALEARLAELERRHGGRVGVAALNLSTGVRV-GHRADERFLMCSTFKALASAMVLARVD +KGVEKLDRRIGFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVSLLLESFGGP +PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRPSRA +QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDTAVAWSPNRGAIVVATYCEI +PTISADERNAVVAEVGRIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / CIP 107115 / JCM 7437 / KCTC 9190 / NBRC 14626 / NCTC 10488 / NRRL B-5397 / IMRU 509) TaxID=446468 RepID=D7AWL3_NOCDD +----ADEFADLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYCSTHKAFSAALVLQRNT +--PEEMEEVVTYDADDVFGHSPVTEQHVDTGLPLMEVADAAVRYSDNTAANLLFDELGGP +DGFEGAMEEMGDDVIEADRVEPGLSRWAPGDTRDTSTPRAMAGSLREFVLGDALPEDRRE +VLTRMLVDNLTGDELIRAGVPEGWEVGDKTGSGNYGTRNDIAVIWPPEGDPIVLAVMSSR +DEEDAEYDNALIAGAAEVVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingosinithalassobacter sp. zrk23 TaxID=2711215 RepID=UPI0013E11D83 +-------FDDLARKFGGGIGIAALDTGSGRRI-DFDSISRYAMCSTFKLPLAGMILARND +AGVLQLDEEIGFGPDDMVPYAPVTERFLDRGMTIAELCEAAVTLSDNVAANLLLRRIGGP +GAFTQWLRSIGDTTTRLDRIEPALNSNLPGDPRDTTTPGAMLDTVNKLVLGNVLAPASRA +GLAQWAVACETGDNRLRAGLPDAWRIGDKTGTSANGAANDVAIVWPPERPPFLIACFIDC +ARVTAAERDAGHAEVARRILREf +>[subseq from] Beta-lactamase n=1 Tax=Jiangella ureilytica TaxID=2530374 RepID=A0A4R4RE27_9ACTN +-----SAVLELERTHDVTLGLSATNLATGVRL-AHRPDERFAILSVFKTLLAAAVLDRAD +--EKRLRHRVWYPPADVVVNSPVTAEHIDTGITIAELCDAALRYSDNTAANLLLREIGGP +RGLTAYARSIGDRVTRLDRWEPELNAAVPGDVRDTTTAAAVARSFENLLVGRALRPADRR +RLTGWMLANTTSAARFRAGLPGGWKLADKTGAGDYGTNNDAGVAWNPAGEPIVIVALTRR +NRVDAPKVDAALADAARLVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces scabiei TaxID=1930 RepID=UPI000A3633A2 +---LSRQLAELEREYTARLGVYAHDTATGRTV-THRADERFPICSVFKTLAAGAVLRDLD +RDGEYLAKRIHYTKEYAEAYSPITGTNVEAGMTVGELCSATVSHSDNGAGNLLLRELGGP +SAITRFCRSLGDRTTRLDRWEPQLNTAEPWRTTDTTTPRAIGRTYARLLLGRALRDADRE +LLTDWLIANSTNVQRFRAGLPADWTLADKTGGGTYGVANDVGVVWPPGRPPLVLSVLSTK +HDPAGPTDNPLVARAAGLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. MA5 TaxID=2508572 RepID=A0A4Q1CQR8_9GAMM +----ATDFAALENACAGRLGVTVLDTASGRRI-GHRQDERFPLCSTFKTVLAATVLDQSR +RVPGLLDRRVPVREADLLSHAPMARRHAGKDLTVRDLCRATIISSDNTAANLLFDVVGGP +PAVTAFLRAQGDSVTRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRLVLGDALAPGARQ +QLADWLIDNETGDACLRAGLGARWRVGDKTGSNGEDARNDTAVLWPVGGAPWVITAYLQA +ADISNDQRASVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces virginiae TaxID=1961 RepID=UPI00099CD60F +---VVARLRELEREYGARLGVYARDTATGRTV-AHRADELFPMCSVFKTLAVAAVLRDLD +HDGAHLAKRIHYTLQDVTDGGSVTERNIAGGLTVAQLCSAAIAQSDNLAGNLLLRELGGP +TAVTRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLAIGDALDSGDRE +QLNRWLLSNTTSADRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPVVLSILSTL +PEPTAPRDNTLIARTAKLLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Jiangella aurantiaca TaxID=2530373 RepID=A0A4R5A6Q0_9ACTN +--ALDPAVRELERAHDVTLGVSARNLATGAWL-AHRAGGRFPILSVFKSIAAAAVLRDLD +--ETRLDHRVWYPPADILLNSAVTAEHLDTGMTVAELCDAAIRYSDNAAGNLLLREIGGP +RGLTAFARSIGDGATRLDRWEIELNSAEPGDERDTSTPAALARTFAGLLTGDLLRPADRR +RLLNWMLANTTSGTRFRAGLPDGWRLADKTGAGDYGTNNDAGVAWNPAGEPIVIVAMSRR +AERDAERVDAALADVARLVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCSS17_007 TaxID=2175646 RepID=A0A2W1UR06_9MICO +---TARAFAALEEQYDARVGVVAIDTADGTGV-GYRSDERFAFASTNKAFIAAAVLDASS +--GEDLDEVVHYGRGDLLAYAPVTSRYVDEGMTVRALVDAALRESDNTAANLLVERLGGV +DGVTRWLRGIGDDVTRVDRVEPDLNTATPGDPRDTTTPAQSAADLRAVLLGDALDAGHRE +LLRSSMAGTTTGDGTIRAGVPDGWSVADKTGTASYGVRNDIAVVQPPGRDPIVLVVFTAH +DRAGAEPSDALVAAATRVAVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI000459ED29 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AALTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0006BA0CF6 +-----GDFAALEKACAGHLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE +RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTISRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA +GAISNEQRALVLAQVGRIA---- +>[subseq from] Beta-lactamase n=2 Tax=Serratia marcescens TaxID=615 RepID=A0A345IR31_SERMA +--AAAKQIKKLEEDFDGRIGVFAIDTGSGNTF-GYRSDERFPLCSSFKGFLAAAVLERVQ +QKKLDINQKVKYESRDLEYHSPITTKYKGSGMTLGDMASAALQYSDNGATNIIMERLGGP +EGMTKFMRSIGDNEFRLDRWELELNTAIPGDKRDTSTPKAVANSLNKLALGNVLNAKVKA +IYQNWLKGNTTGDARIRASVPADWVVGDKTGSCGYGTANDYAVIWPKNRAPLIVSIYTTR +KSKDDKHSDKT------------ +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. CCGE532 TaxID=2364272 RepID=A0A387GW27_9RHIZ +----DAQLAVLESKHPGRICVGILDMASGKRI-EHRAGERILMCSTFKALAAALVLTRVD +KGEEKLDRRIRYSEGDIIGGSPATKLHVGDGMTVAELCAAAVTLSDNTAANLLLASFGGP +KALTAFCRSLGDEMTRLDRIEPALNYDTPDDQRDTTTAIAMLENLRRLLFTDVLSAASRS +QLAAWLITNKTGDARLRAGVPKDWLVGDKTGTNGAGNANDIAVLWPSNRAPILVTAYCEI +PSIAANERNAIIAEIGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas carotinifaciens TaxID=1166323 RepID=A0A1G7NMH0_9SPHN +---LADLAADLERRIGGRLGVAHFVPRTEMLR-GHRLEQRFPMCSTFKLLAVAAILARVD +GRRDHLDAPVAVREADRVAHAPVTGPHIGGTMTLADLCAAAMQESDNVAANLLLRRLGGP +AGITAYAQSLGDRATRLDRWEPDLNSALPGDPRDTTTPAAMARLAGRILEGDSLRPPSCA +LLRRWMTQTRTGLTRIRAGLPHSWSVGDKTGSGANGTANDVAWFHPPGRDPAILAIFLTD +TQASATARDAVFATIAHHVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=UPI000642545F +-qTLAQRLAGIERRTRGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFVLTAAVLQRVD +RGELSLQQRLQVRASDMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP +PGLTRFLRTLCDAQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDVLRPASRQ +CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG +AKVDEAARDAALKEVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007528A93 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFARASGDTLFRLDRWEPELNTARPGDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Kiloniella majae TaxID=1938558 RepID=UPI000A279779 +------TVIGLEESIGGRIGVAVYDLQTGQNW-EYRSDEKFPMSSTFKPFACAALLTQNE +RKDETLERMVSVSRDDLVSYSPVIEKYADDGVSLRMSCEATVSISDNTAGNLVLKEIGGP +EGFTKYMRSIGDNTTRLDRWETALNEAQPDDLRDTTSPKAIATSLQKLLLEDALSPEARI +EITNWMLNDQVADDLFRSRLPKEWKIADKTGAGGFGSRGIIAVIWPPSRKAVVASVYMTG +NDADFKTRNAAIAEIGAAIFE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-378 TaxID=1463904 RepID=UPI0004CC73A6 +----VRRLRALEREYGARVGAYARDTGTGRTV-RYRADELFPMCSVFKTPAAAAVMRDLD +HDGGFLARRIHYTQDDVTSGGSVTGRNVAGGLTVAELCSAAIAQSDNGAANLLLRELGGP +TAITRFCRSLGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLALGDALAPRHRE +LLTRWLVSNTTSGDRFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPSRPPVELAVLTTM +ADAAAPRQDALLARAAAALA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI000250B61C +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTRLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCSS17_005 TaxID=2175641 RepID=A0A2W1R4Z5_9MICO +--ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTVKVFIAAAVLDASS +--DADLATVVHYDRGDLLEYAPVTREHVDTGMTVRELVDAALRSSDNTAANLLVERLGGL +GAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR +ADAGAEPSDALVAAATRTAV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. t39 TaxID=1828156 RepID=A0A5Q4TE16_9ACTN +----AREFMALERAFDARLGVYAIDTGTGEEI-AWNDRERFPYASTFKALAAGAVLDEYG +--LRGMDRVIRYTADDLVDGSPVTEKHVATGMTLGELCDAAVRFSDNTAGNLLLGELGGP +GGLDAALEDLGDHVTQMDRIEPELGEWAPGDDRDTSTPRALTHDLRAFVLGNVLKKGERD +RLTTLLRTNTTGGETIRAGVPDTWVVGDKTGTATYGGRNDIAVVWPRGGAPIVMAILSNR +PEKDAEHDNALIARAASVVA--- +>[subseq from] Beta-lactamase n=1 Tax=Roseovarius lutimaris TaxID=1005928 RepID=A0A1I5B8S4_9RHOB +-dALSRSVQDVEARIGGRIGYAMSDLHSGQTW-GYRADDRFPVSSTFKALLCGVILARVD +AGEEALDRLVTFGAGDLVTYSPVTETRLATGMTVGELCKSAVTISDNTAGNLLLATVDGP +EGFTAALRDIGDTTTRLDRWETALNEGAPGDMKDTTTPQAALSTLRALLFGEVLTPTSRR +QLADWMIADAVADDLLRASLPEAWVIGDKSGAGGHGSRSIIAVIWPTPDRPVLAAIYMTE +NDADMPARNAAIAEIGAAMFA-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia kunmingensis TaxID=630975 RepID=A0A543E1Q5_9PSEU +-------LLELERRFDARLGVYALDTGSGATI-AHRADERFAFCSTFKGLAAAAVLHRNP +--MSHLDTVVTYGEGDLLKSAIVTREHVASGMTIGQLCDAAVRFSDGTAGNLLLRDLGGP +AELTAYTRGLGDTVTRMDRVEPDIVEATPGDPRDTSSPRALGTDYQRIVLDDALPGEARA +FLRDLLERNTTGAERVRAGVPRGWTVADKTGTGDYGTLNDIAIVWPPDRAPLVVSVMSSK +AAQDAPYDQAVIAEAAAFVM--- +>[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=2 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0009B9054C +--AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=2 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0009C0ED8E +--AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. CNS-639 TaxID=1169153 RepID=UPI00037613F3 +----ADEFADLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYCSTHKAFSAALVLQRNT +--PEEMEEVVTYDADDVFGHSPVTEQHVDTGLPLVEVADAAVRYSDNTAANLLFDELGGP +DGFEEAMEEMGDDVIEADRVEPGLSRWAPGDTRDTSTPRAMAGSLREFVLGDALPEDRRE +VLTRMLVDNLTGDELIRAGVPEGWEVGDKTGSGNYGTRNDIAVLWPPEGDPIVLAVMSSR +DEEDAEYDNALIAGAAEVVVE-- +>[subseq from] Beta-lactamase n=2 Tax=Arsenophonus nasoniae TaxID=638 RepID=D2U361_9GAMM +---------KKKKKLNSRIGVAIIDTTDNVTI-SYRGNERFPLNSTFKALLCGRLLHQVD +NGKIVLTESVQFQKEQLVTYSPVTEKFTSPLMNWQQLCSAAISYSDNTAANLIAEKIGGP +ASFTRFLRTIGDSITRLDRFEPELNSAIPGDMRDTTTPVAISQTLQKLVLGDVLQPSSRQ +QLRQWMEDDKVANALLRSVLPTQWKIVDKTGSGDYGSRSIISLVWPENRQPLIIAIYITQ +TKATLAQSNEAIARIGKVIFS-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium paragordonae TaxID=1389713 RepID=A0A4V6PMN0_9MYCO +--DLTSRFTEIERRYQGRLGVYVPASGATPAI-AYRAEERFALCSTFKAPLVAAVLHQYP +--LSYLDQRVTFGKADISSPSPIAEQHINTGMTVGEMCDAAIRYSDNTAANLLLNRIGGP +AGFTAYLRSLGDSTSRLDHAEPELNRDPPGDERDTTTPHAIAVTMQQLVLGDALPQDKRA +MLTEWMARNTTGGKRIRAAFPADWKVSDKTGSGDYGRANDVAVVWSPAGTPHVIAIYTDI +AGYYAQPNEAFVADAARVVAS-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CS081A TaxID=2162709 RepID=A0A2T7JJQ3_9ACTN +---HRREFRALEDAFDARLGVYAIDTGTGREV-AYRDGERFPYASTFKALAAGAVLRKES +--LSGMERVVRYTEDELVDPSPVTEKHVGTGMTLDALADAAVRHSDNTAGNLLFEELAGP +KGLQAVLRSIGDDVTRMDRIEPELGDWRPGEVRDTSSPRALARDLRAFVLGDVLRAPERE +RLTTWLKTNLTGDETIRAGVPDTWVVGDKTGTATYGGRNDMAVVWPPDGAPIVMAILSTR +SDREAKPDNRLIARAASVVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 303MFCol5.2 TaxID=1172181 RepID=UPI0009973144 +---VTDRLRDLEAGHGARLGVFAYNVRTGHSV-RYRADERFPVCSLFKTLAVAAVLRDLP +--EGTLDRRVFWTSTDVVENSPVTQDHVADGMTIAELSAAAIQRSDNTAGNLLLRELGGP +TAITRFARSVGDRVTRLDRWEPDLNSAEPDRVTDTTTPYAIGRTYARLVLGDALAPADRR +RLTDWMLGTITSANRFRAGLPPTWTIADKTGGGWYGANNDAGIAWTPDGAPVVLVVQLTK +PDREAAYDNELIVKTAGVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium guangxiense TaxID=1325115 RepID=UPI001008C035 +------ELEAYERESGGRVGVHAENLATGKKL-GWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAVIPYGKADLLEYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARVGGP +AALTAFWRSLGDSTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVVGEALSPGSRA +LLTDWMVNCKTGANRLRGGLPAGWTIGDKTGFNGKDAAGDIVVAWPKPDTPILITTYVQG +GAPTAAQIEAVFARIGRMVAE-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0006AC52AB +----ATDFAALEKACAGRLGVTVLDTASGRRI-GHRQDERFPLCSTFKTVLAATVLDQSR +RVPGLLDRRVPVREADLLSHAPVARRHAGKDLTVRDLCRATIITSDNTAANLLFDVVGGP +PAVTAFLRAQGDSVTRSDRLEPELNSFAGGDPRDTTTPAAMAATLQRLVLGDALAQGARQ +QLADWLIDNETGDACLRAGLGAHWRVGDKTGSNGEDARNDTAVLWPVGGAPWVITAYLQA +ADISNDQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Nocardioides albertanoniae TaxID=1175486 RepID=A0A543A1S6_9ACTN +------SIAALEKRHQRRLGVWATNMRTGRTL-AHRADERFPMCSTFKTLLAAQILRDLP +--ARTLQQRLTWDESDVVANSPVTSLTTRNGLTVAQLAEATLTRSDNTAANVLLHLVGGP +SAITGFARSLGDTVTRLDRWEPELNSAIPGDPRDTTSPRAIAQTYTRLLLGDALARADRD +QLTTWMLANQSTVTRFGAGVPAGWRLADKTGGGDYATRNDVGVTWTPDGAPIVIAALTRS +DDPAAQPLDAPLADIAATVCA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sioyaensis TaxID=67364 RepID=A0A4Q1R5B1_9ACTN +-dELSRRLTDLEQQHSARLGVFAHNPATGRSV-LHRADERFPMCSLFKTLAAAAVLRDLD +HHGEFLAKRIRYTAKDVRDYAPVTGTNLARGMTVADLCAAAIAASDNAAGNLLLRELGGP +TAITRFCRSIGDRTTRLDRYEPDLNSAEPWRITDTTSPRAIGQTYARLTLGTALTPKDRK +RLTEWLRATTTGGEKFRAGLPSDWTVADKTAGGKYGTNHDAGLTWPPGGSPIVMAVLTTK +REPDATADNPLIAKTAALLA--- +>[subseq from] IMI-9 n=2 Tax=Enterobacter TaxID=547 RepID=A0A1D8RES1_ENTCL +-----DEIKNLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ +DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSVKTLALGNILNEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +NEKEAKHDDKVIAEASRIAID-- +>[subseq from] class A beta-lactamase n=1 Tax=Kosakonia cowanii TaxID=208223 RepID=UPI00111AE30A +-------IARLEEKLHARIGIAVIDTASGKSV-SYRGDERFPLNSTHKALLCGALLSKVD +RGEFALSDTTQFSKETLVDYSPVTSKFVAPKMSWQQVCGAAISYSDNTAANLAAQKLGGP +QKVTAFFAGLGDNVTRLDRKEPELNSAVPGDLQDTTTPLAVSRTLEKLTLCDALKPESRA +QLVQWMKDDKVADALLRASLPSGWKIGDKTGAGAHGSRSIISVVWPKKGQPIIVSVYITQ +TEATLAQSNDAIARIGKSIFE-- +>[subseq from] BCL family class A beta-lactamase n=1 Tax=Bacillus clausii TaxID=79880 RepID=UPI000BA5C5A2 +----EAVFKALEEEYAARLGVFALDTGTGQTV-SYRSDERFTYASAHKPLAVAVLLQQKS +--IEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANFIFDEIGGP +EGFKEGLRAIGDTVTEPERIEPELNHVEPGEIQDTSTPEALAKSLQEFALGEALPADKQE +LLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILWPPEKEPIILAVLSSK +DEKDAEYDDELIAKATEEVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. H021 TaxID=1519486 RepID=UPI0006AF71F5 +----VRRLRALEREYGARVGAYARDTGRGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD +RDGEFLARRIHYTQGDVTAGGSVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP +TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE +LLTRWLVSNTTSDDRFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK +PDAAAPRENALVARAAEVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Cohaesibacter intestini TaxID=2211145 RepID=UPI000DEA640A +-qELGETVAAWETKLDGRIGVILRDTASDWTY-SHRSDERFPMASTFKSLLCGAVLGEVD +AGRESLTNQVTYSKKDLVYWSPITQKHLASGLPISALCEAAVTMSDNAAANLLLKRVNGP +AGLTGFLRGIGDATTRLDRWEPEMSKGTPKDPRDTTSPRAITTSLHNLLFGGALQPASAA +LLKQWMIDDQVADKLIRPHVPDGWIIGDKTGSGGHGTRAIVAFLQTPKGQTFMAAIYITQ +SKAGKDARNQAISAIGRAMIS-- +>[subseq from] Beta-lactamase n=1 Tax=Histophilus somni TaxID=731 RepID=A0A4Y8QRJ7_HISSO +--TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP +--EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV +EQYQRILRQLGDNVTHANRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT +ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ +FTEEAKFNNKLVEDAAKQVFH-- +>[subseq from] Beta-lactamase n=3 Tax=Moellerella wisconsensis TaxID=158849 RepID=A0A485A2M5_9GAMM +---TLDRIKTTEEQLNGKVGYTELDLVSGKILeSYRSKERFPMMSTHKVLLCAAILSRVD +TGQEQLDRRIMYSQHNLDEYSPVTEKHLVDGMTVGELCDAAITMSDNTAANLLLESMGGP +QKLTSFLRKTGDQITRLDRYEPELNEAFPSDERDTTTPESMAQTMRNLFTGKILTPTSQA +KLIDWMEADRVAGQLFRSVLPAGWYIADKSGAGKHGSRGIVALLGPYGKPSRIVIIYMTQ +NEATMNELNRHIADIGNTLIKNw +>[subseq from] Beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A5K8C2U2_ALCXX +---FQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDVLKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] ROB family class A beta-lactamase n=1 Tax=Pasteurellaceae TaxID=712 RepID=UPI000E31F4FB +--TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP +--EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV +EQYQRILRQLGDNVTHANRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT +ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ +FTEEAKFNNKLVEDAAKQVFH-- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_045 TaxID=2175629 RepID=UPI000DA8F05B +--ATARAFAALERRYDARLGVVAVDTGDGRTI-AHRAGKRFAFASTIKVFIAAAVLDASS +--DADLATLVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTATPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR +ADPGAEPSDALVAAATRAAV--- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus clausii TaxID=79880 RepID=A8RR46_BACCS +-----AVFKALEEEYAARLGVFALDTGTGQTV-SYRSDERFTYASAHKPLAVAVLLQQKS +--IEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANFIFDEIGGP +EGFKEGLRAIGDTVTEPERIEPELNHVEPGEIQDTSTPEALAKSLQEFALGEALPADKQE +LLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILWPPEKEPIILAVLSSK +DEKDAEYDDELIAKATEEVI--- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio jasicida TaxID=766224 RepID=UPI0005EF2C94 +--KLNEDISAIEQHIAGRVGVAIWDTQSNEHW-DYRGDERFPMMSTFKTLACATMLKDMD +SGKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTATNIVLRSIGGP +HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium flaccumfaciens TaxID=2035 RepID=UPI00058EE7D4 +--AAARAFASLERRYDARLGITAVDTGSGRTL-VHRAGERFAFASTVKVFIAAAVLDGSS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTSVDRVEPDLNQATPGDRRDTTTPERFAADLRAVLLGDVLDAADRR +VLRDAMLGSTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSQ +VDPKADPSDPLVAAATRAVV--- +>[subseq from] ROB family class A beta-lactamase ROB-3 n=8 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A6B9LD83_HAEPR +--TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP +--EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV +EQYQRILRQLGDNVTHANRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT +ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ +FTEEAKFNNKLVEDAAKQVFH-- +>[subseq from] Beta-lactamase n=1 Tax=Comamonas sp. JNW TaxID=2170731 RepID=A0A363RNP6_9BURK +--QFAQAMQDLERSVGGRLGVSALNTVTGAAL-GWRQNERFAMCSTFKMLLAAQVLSRVD +AGQDRLDAALTFDRSVLVEHSPVTEKFAGKAMTVDALCDAIMTVSDNGAANLLLERVGGP +ASFTAYMRSLTDPVTRLDRIEPAMSESKPGDVRDTTSPQAMLSSMRALTLGTALSPASRE +RLVGWMEANTTGDHCLRAGAP-GWKVADKTGSGPN-TRNDIGLLWAPGATPILVTTYLTE +CKAEPKARDAALARVAAELVKLw +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-2799 TaxID=1463844 RepID=UPI0004CC7584 +--ALRPELAALEKRYGARLGVYAHNTRTGAAV-AYRADESFAMCSTFKAIAAAAVLRDHG +-GRAALGEVIHYPPTDILSNSEQTKAHQETGMALGDVCAAAIQYSDNTAGNLMLRRIGGP +AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPRALGRTFELLTLGRALSDGDRE +QLVGWLRGNTTSGKRFGAGLPSDWVLADKTGTGSYATANDLGVAWTGRGTPLLLSVLSTK +PAPDAAVDEALIEETARLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. SK17 TaxID=2057741 RepID=A0A2K8YKQ6_9BRAD +--SIEHRLKDVEVQSRGRLGVALLDTATGKLI-GNRIDQRFAMCSTFKALAVALVLARVD +RGEEQLDRRVVFSERDLVPPSVATQPHVGPGMTVAELCEAAVTVSDSTAANLLLASFGGP +AALTAYLRSLGDPVTRLDRVELDLNIVKPGEQHDTTSPAAMARTLQRLLLGDALSEPSRA +RLTGWMAGAKDATTRLRAGLPQGWRIANKPGTWKGIATNDVGVIWPPGRAPIVVAAYLAD +APTPVATQEAILAEIGRIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0R5RPZ5_9BACT +--TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP +--EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV +EQYQRILRQLGDNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT +ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ +FTEEAKFNNKLVEDAAKQVFH-- +>[subseq from] Beta-lactamase n=1 Tax=Bibersteinia trehalosi USDA-ARS-USMARC-192 TaxID=1171377 RepID=M4R2V5_BIBTR +--TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP +--EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV +EQYQRILRQLGDNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT +ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ +FTEEAKFNNKLVEDAAKQVFH-- +>[subseq from] Beta-lactamase ROB-1 n=34 Tax=Bacteria TaxID=2 RepID=BLA1_ACTPL +--TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP +--EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV +EQYQRILRQLGDNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT +ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ +FTEEAKFNNKLVEDAAKQVFH-- +>[subseq from] class A beta-lactamase n=1 Tax=Polymorphobacter fuscus TaxID=1439888 RepID=UPI001269C98D +--DLAAAVKTAEAASGGRVGLAVHDTATGRRF-SHRGGERFAMASTFKTLLAAAVLARID +AGEDRLDRAIPVAQGDILGNSPFAERRIGRTASVAELAEAAIIYSDNAAANLLLPSVGGP +AGLTAWLRRTGDPVTRLDRNEPTLNEARPGDPRDTSSPDAIAATWQRLLVGPVLTPASRA +LLTGWLVGNTTGDTRLRAGLPKGWRVGDKTGTGRNGSVNDIAIAWPDRTGPVIIASFINE +GTAAAEVLYALHADLARAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNS615 TaxID=1169158 RepID=UPI000368A68A +----VREFTELEDRFEARLGVYAVDTGTGREV-AHNEDERFAYASTFKVLAAGAVLREHS +--LSGLDQVITYSADDLVPHSPVTAKRVGTGMSLAELCDAAVRLGDNTAANLLLDEMGGP +RGLDAALEEIGDDVTRMERRETQLNEWSPGSLSDTSTPRALARDLRAYVLEDALGKGERA +QLTEWLRTSATGSELIKAGVPKDWMVGHRAGAGGYGVRNDIAVVWPPDSAPIVIAIMSNG +LRRDADHDDRLIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. WB9 TaxID=2594007 RepID=A0A516WPF8_9NOCA +---LDATIDALEAQHSTRIGVTAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLQMTE +DGSTSLDKTVEIEPGDLVENSPVTAAAAGTPMTLAQIAEAALTQSDNTAGNYLLREIGGP +QAVTDLAREVGDGSTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD +QLLEWMRASKTSDKRMRAGLPTGWTATDKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS +LTEDAQGNNQAIADTTAAVLE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SAA3_KLEPN +---------------RGRVGMIEMDLASGRTLtAWRAEERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIT--- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. HM190 TaxID=2695266 RepID=UPI00135AE053 +----APAFRELEREFDARLGVYAVDTGTGRSV-AYRADQRFAYASTFKALAAGAVLRKHA +EGGDGMEKVVTYGRDDIVENSPVTEDFVETGMTLSGLCAATLWYSDNTAANLLLDELGGP +DGLERVLEELGDDVTEMDRLEPDLSEGRPGDVRDTSTPRAMAGSLRAFLLGDALERDDRA +LLRTWMETNRTGGTLVRAGVPDGWTVADKSGSAGYGGRNDIAVLWPEDGNPVVLAVLTSR +DKQNAERRDALVARAATAAI--- +>[subseq from] BCL family class A beta-lactamase n=1 Tax=Bacillus clausii TaxID=79880 RepID=UPI000BA53901 +-----AVFKALEEEYAARLGVFALDTGTGQTV-SYRSDERFTYASAHKPLAVAVLLQQKS +--IEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANFIFDEIGGP +EGFKEGLRAIGDTVTEPERIEPELNHVEPGEIQDTSTPEALAKSLQEFALGKALPADKQE +LLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILWPPEKEPIILAVLSSK +DEKDAEYDDELIAKATEEVI--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis rubida TaxID=112413 RepID=A0A1I6B3N5_9PSEU +----QPDFAALEKAFDARLGVYAIDTGDGREV-AYHADDRFAYASTHKVFNAAAILHRGD +----DLTRTVTIRQSDLVPNSPITEKHIGEQMSLQSVLDAALRYSDNTADNLMFREIGGP +AGLAAELRRLGDTVTRVDRIEPALNETSPGDVRDTTTPRAWSKDLRAVALDSGLPADKQA +VLTKIMRANTTGAHVIRAGVPADWQVADKTGSADYATRNDIAVLWPPHRAPIVLAVLSDR +RQKDAKTDDKLIARAAAAVVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Kosakonia oryzae TaxID=497725 RepID=UPI0007DE29A0 +---LAEVVRLQEQQLGARIGVAVVDTASGTTA-SYRGDERFPLNSTHKALLCGALLSQVD +KGELALTDTTQFPRSALVVYSPVTEKFVAPAINWQQLCSAAVSYSDNTAANLLTQKLGGP +AAITRYLQTLGDSVTRMDRFEPELNSAIPGDLRDTTTPLAVSRTLQKLTLGTALKPDSRA +QLIQWMREDKVADTLLRSTLPAGWTIADKTGAGDFGSRSIISVVWPENNTPRIVVIYITN +TKATLKQSNAAIASLGKTIF--- +>[subseq from] Beta-lactamase n=5 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A0L8TRZ5_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDKRW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTQFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia amamiensis TaxID=404578 RepID=UPI000A011749 +------RLAELERKFGARLGVYALATGTGVTI-AYRADERFAFCSTFKGLAAAAVLQRNP +--LSHLDTVVTYTEADLTKNAAITPRHVTTGMTIGQLCDAAIRYSDGTAGNLLLRDLGGP +AELTAYVRSLGDTVTRMDRIEPLITEATPGDPRDTSSPRALGTDYQKIVLADTLPDEKRA +FLRDLLERNATGARRIRAGVPQGWTVADKTGTGDYGTLNDIAIVWPPGSAPLVVAIMSSK +ADRDAAYDEALIAEAAAYVVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia pneumoniae TaxID=228601 RepID=UPI000314CCFF +-----VRLAELERKFDARLGVYALATGTGVTV-AYRADERFAFCSTFKGLAAAAVLQRNP +--LSHLDTVVSYTEADLTKNAAITPRHVATGMTIGQLCDAAIRYSDGTAGNLLLRDLGGP +AELTAYVRGLGDTVTRMDRIEPLITEATPGDPRDTSSPRALGTDYHKIVLGDALADEKRA +FLRDLLERNATGARRIRAGIPQGWTVADKTGTGDYGTVNDIAIVWPPGSAPLVIAIMSSK +NDRDAAYDEALLAEAAAYVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Natronospirillum operossus TaxID=2562806 RepID=A0A4Z0WEX8_9BACT +-----SEIERIESHLDARVGFAAYDTESDMRW-EYNSEQRFALASTFKTLACAALLARVD +AGSEQLTRSISVSSSDLVTYSPVLEEYADNRINLSELCEATMTISDNTAANLILQSLGGP +ESVTAFARQLGDDVTRLDRWETELNEAVPGDERDTTTPNAMIGNLEQLLLGNVLTEESIN +LLKTWLINNQVADDLFRSVKPDGWIIGDRTGAGGFGSRAITAVIWPPERKPIFVAFYITE +TTASFEERNAAIEQLGRVLME-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI000C1B5FAC +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=W0C0S5_ENTCL +-----DEIKDLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ +DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +YEKEAKHEDKVIAEASRIAID-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. H13 TaxID=2605988 RepID=UPI0012387BBC +----ADEFADLEEEFDARLGVYAVDTGTGEEV-AHRPDERFAYCSTHKAFTAALVLQQNT +--PEEMEEVVTYDADDVFGHSPVTGQHVDTGLPLVEVADAAVRYSDNTAANLLFDELGGP +DGFEEAMEEMGDDVIEADRVEPGLSRWTPGDTRDTSTPRAMAESLREFTLGDALPEDRRE +VLTRMLVDNLTGDELIRAGVPEDWRVGDKTGNGSYGTRNDIAVLWPPEGDPIVLAVMSSR +ETEDAEYDNALIAGAAEVVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Dyella sp. 4M-K27 TaxID=1927959 RepID=A0A432M684_9GAMM +--DANARLAALERQYGGRLGVAILDTANGSRA-SYRADERFLLCSTFKMLLAAAVLARVD +RGTEQLDKRLEFGKDAVVDHSPVTSLHIGPPMSIAELCKAAVSVTDNTAANVLLKHLGGP +HVITDLARQLGDPLTRLDRYEVELNRPAPDGVSDTTTPNAMLGNLQKLLLGNGLSEASRK +QLTEWMLGAVTGQKLVRAGVPAGWKIAEKTGGGNF-QTNDVAILWPPGRKPLLAAVYYEN +AARDIDERSAVLASVGRIMA--- +>[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus sp. 6R TaxID=1911587 RepID=UPI00090C285A +-----EAFRLLEKEYDAKLGIYAMDTGTGKTV-SYRAENRFAYASTHKVLAVGVLLQKMN +--VNQLEETVLIKEDDLVNYNPITEKHVNKLMTWNELSDASMRYSDNTAANYILKRIGGP +AGFKQALRDIGDDVTKPERIEPELNKVKPGETRDTSTPKALATSLQTFTMGDVLTKQKQD +LLVNWLKRNTTGDNLIRAGVPEGWEVGDKSGAASYGTRNDIAIIWPPNEDPIILAVLSSR +DEEDAEGNDELIAKATEEVM--- +>[subseq from] Beta-lactamase n=2 Tax=Rhodococcus opacus TaxID=37919 RepID=K8XNR9_RHOOP +---LDATIDALEAQHSTRIGVTAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE +DGSTSLDKTVVIEPGDLVENSPVTAAAAGTPMTLAQIAEAALTQSDNTAGNYLLREIGGP +QAVTDLARDVGDGSTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD +QLLEWMRASKTSDKRMRAGLPTGWTATDKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS +LTEDAQGNNQAIADTTAAVIK-- +>[subseq from] Beta-lactamase n=2 Tax=Rhodococcus TaxID=1827 RepID=E0D3G0_RHOOP +---LDATIDALEAQHSTRIGVTAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE +DGSTSLDKTVVIEPGDLVENSPVTAAAAGTPMTLAQIAEAALTQSDNTAGNYLLREIGGP +QAVTDLARDVGDGSTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD +QLLEWMRASKTSDKRMRAGLPTGWTATDKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS +LTEDAQGNNQAIADTTAAVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium canettii TaxID=78331 RepID=UPI0005B3C881 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPRAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGAGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium flaccumfaciens UCD-AKU TaxID=1292022 RepID=A0A022LPF9_9MICO +--AAARAFASLERRYDARLGITAVDTGSGRTL-VHRAGERFAFASTVKVFIAAAVLDGSS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTSVDRVEPDLNQATPGDRRDTTTPERFAADLRAVLLGDVLDAADRR +VLRDAMLGSTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSQ +VDPKADPSDPLVAAATRAVV--- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium flaccumfaciens TaxID=2035 RepID=A0A502C3C3_9MICO +--AAARAFASLERRYDARLGITAVDTGSGRTL-VHRAGERFAFASTVKVFIAAAVLDGSS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTSVDRVEPDLNQATPGDRRDTTTPERFAADLRAVLLGDVLDAADRR +VLRDAMLGSTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSQ +VDPKADPSDPLVAAATRAVV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. H021 TaxID=1519486 RepID=A0A0M9Z3R9_9ACTN +----VRRLRALEREYGARVGAYARDTGRGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD +RDGEFLARRIHYTQGDVTAGGSVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP +TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE +LLTRWLVSNTTSDDRFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK +PDAAAPRENALVARAAEVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Geodermatophilus sp. LHW52908 TaxID=2303986 RepID=A0A372IYQ8_9ACTN +----EHALAGLEARFDARLGVYAVDTRSGRSI-AHRAYERFAYASTVKVLAAAVVLDRTT +--PAELAQAVPYDSSELVAHSPVTEERLAAGMTLGELAEAALRHSDNTAANLLLDRIGGP +QALDAALAAFGDDVTTVVRDEPELNDTAPGDDRDTSTPRALAADLRAFAVGDALAEEDRA +QLVDWMTGNATGRALVRAGVPADWHVADKSGTAAYGTRNDIAVVYPPEGEPIVVAVMSDR +DLPDDEHDDALVAEPARIVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Kurthia sp. 3B1D TaxID=1562256 RepID=A0A433RUY9_9BACL +---PQQDFKELEKKYDVRLGIYVIDTATNKKI-AYHANERFAFTSTYKALAAGVLLQNAS +--LEQLETVILYTKDDLVAYSPVTELYTDTGMTLREISEAAVRYSDNTAGNLLFHAIGGP +KGFEQSLRKMGDKTTYANRFETELNTAIPGDKRDTSTAKALAIDLKKYTIDSTLSIEKRQ +LLLDWMADNKTGDALIRAGVPTDWKVVDKSGAGSYGTRNDIAVVFPPNRAPIVLAILSSR +SEQNATYDNQLIEEATRVIIK-- +>[subseq from] Beta-lactamase n=1 Tax=Photorhabdus luminescens subsp. mexicana TaxID=2100167 RepID=A0A4R4JJQ5_PHOLU +--RLATVVKQEEQTLNARIGVAVIDTASDKMV-SYRGNERFPLNSTFKALLCGVLLSEVD +KGKVALTDAIQFNKTELVEYSPVSEKFVVPAMNWQQLCSAAVSYSDNTAANLIAKKVGGP +VAMNLFFSGLGDNVTHLDRYEPELNSAIPGDKRDTTTPIAVSQTLQKLTLGEVLEPSSRQ +QLVEWMRDDKVADALLRSVLPAGWKIADKTGAGDYGSRSIISIVWPKDSSPLIVAIYITQ +TEATIAQSNEAIARIGKIL---- +>[subseq from] Class A beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520D439_9BURK +-----ESFRRIEAASGGRLGVFMLDTGSGRTL-AYRADERFPMCSTFKFLAAAFVVQRAD +SGLDDLARAVAIPPAELVPYSPVTGPNAGRTMAMAQLCEAAVAVSDNTAANLMLASFGGP +AGLTGFARALGDRVTRLDRNEPLLNEGTPGDERDTTTPAAMAGLMRKLLVDRTLEAASRE +RLQAWLVGNTTGDRQIRAGLPPGWRVGDKTGSGGNGTSNDIAIVWPPDAAPLLVTAYLTG +ATATVAQRQATLAAVGALV---- +>[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora mediocidica TaxID=58352 RepID=UPI00056B1FB2 +--DVTRALGGLEREHGARLGVFARNTATGRTV-LYRADELFPICSVHKTVTAAAVLRDLD +RDGGFLAERIRYTAQDVADYSPITGEHLANGMTVAELCAAALDYSDNTADNLLLRQLGGP +EAITRFCRSIGDRTTRLDRWEPALNSAEPGRVTDTTSPRALGRTFSKLLLGTALSAPDRE +QLTSWLLADTTSAARFRAGLPKDWALADKTGTGDYGTTNDAGIAWTPRRTPLVLSVLSTK +TDSAAPADEPLVAKTAALLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces fulvissimus DSM 40593 TaxID=1303692 RepID=N0CPN8_9ACTN +---TDRAFAGLERKFDARLGVYAVDTGDGRIV-AHRPDERFAYASTCKALLAGAVLAKKS +--LPQMERLVRYGEEEIISNSPITEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP +RGLQDALRGLGDRITRCDRYEVALSDATPGDLRDTSTPRALATDLRAYVLGPALPAGKQA +VLADWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVRPPGGAPIALAVLSRR +DTKDAEPQDALIAGAAKVALEAf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. F-3 TaxID=1840095 RepID=A0A170W448_9ACTN +----TGRLRALEEEYGARLGVYARNVRTGRTI-RHRADTLFPICSVFKPLAAAAVLRDLD +RNGEVLSRRIHYTADDLVDNSDRTRENLATGMTIAELCDVAIRWSDNTAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRITDTTSPRAIGRTYARLVLGDALSRADRS +RLTHWLLHNRTSGTRLRAGLPGTWTVADKTGGGAYATNNNVGIAWTEDGTPLVLAILSRT +FDEDAVQDDTLIARTAAALA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia niwae TaxID=626084 RepID=UPI0007A45967 +----HDRLLELERKYDARLGVYARATGTGVIV-AHRADERFAFCSTFKGVAAAAVLQRNP +--RSHLDTVVTYTRDDLLKNASVTPRHLDTGMTIRQLCDAAIRYSDGTAGNLLLRDLGGP +AELTAFARSLDDTVTRMDRIEPAITEATPGDPRDTTSPRAFGELYHRIVVGDALPSDKRD +FLRDLMERNATGAQRIRAGTPQGWTVADKTGTGDYGTLNDIAIVWPPASAPLIVAVMSSK +AARDAAYDQALLAEAAAYVVD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0P0G9C0_ECOLX +---------------------------------------RFRMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGAS----- +>[subseq from] Beta-lactamase n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A317I3D6_9PROT +------ALETYERESGGRVGFYAENLSSGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEDQLAAMIAYGNADLLDYAPVAKENFAKRMSVGDMCKASVEVSDNTCANLLLARIGGP +AALTAFWRSIGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNFRRLALGEALSAASRA +QLTDWMVNCKTGAKRLRAGLPGTWKIGDKTGNNGKDASGDIVVAWPKPDTPILITAYTQG +GTPNAAQIDAVFASIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bryocella elongata TaxID=863522 RepID=A0A1H5ZCR0_9BACT +--DFESEMKTLEGASGGRLGVAMYQPSTGARH-GYRAAERFPMCSTSKLLAVAAMLHVID +REQDHLDRPIIFSKRDIAGYSPATSSKLGPPMTLRELCEAAITLSDNTAMNLLLEELGGP +NAWTAYARTLGDTVSRLDRNEPTLNECRPGDPRDTTTPEAMLADTQKLILGGALSAHSRD +LLTGWMIDCKTGDQKIRAGIPAAWRVGDKTGNSGQGTSNDIAIIWPTGQQPWLLTVYLND +AKVSDAQQSAVSANVARVCV--- +>[subseq from] class A beta-lactamase n=1 Tax=Azoarcus sp. HKLI-1 TaxID=2686016 RepID=UPI0013578CC2 +--ALQARLAGLEAAARGRLGVCILDTESGREH-GYRADERFMMLSSFKLLACALVLHRVD +AGEDSLDRRIVYGREALLPWSPVTEQHADGGMRLAQLCEATITTSDNAAANLILATYGGP +ARLTAYVRALGDDVTRFDRIEPALNLPGDDDALDTTSPRAMVRTMQTLLLGDALSIGSRL +QLQRWLLGSTTGANRLKAGLPSDWKIGDKTGTNQR-DANDIAIVWPPGRPPLLVAAYLAG +SAADGAQKDRTLAAVGALVRDVf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. F001 TaxID=1510026 RepID=A0A4Q6IPE6_9ACTN +---TTAEFRALEREFDARLGVYALDTGTGRSV-GHRADDRFAYASTFKALAAGAVLRKYG +--TDGIDKVVRYSRDDLVENSPVSENFVETGMSLRGLCAATLWYSDNTAVNLLLDELGGP +DGLEKVLEEFGDDVTEMDRYETEMSEGTPGDIRDTSTPRAMAGSLRAFLLGDALKRDERE +LLRQWMTTNMTGRTLIRAGVPDDWDVADKSGTAGYGGRNNIAVVWPDDGNPIVMAVLSTR +DKKDAERRDALLAKAATVAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium canettii TaxID=78331 RepID=UPI0002A577E0 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00045AE252 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI000459EFE3 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase n=20 Tax=Mycobacterium tuberculosis complex TaxID=77643 RepID=BLAC_MYCBO +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea solani TaxID=1144553 RepID=A0A1H5Z254_9ACTN +--QVKKELRALEASYNGRIGAYAIDTATGRTV-AYRSGERFPLLSTFKAPLCAAALHRAR +TEPGLMDKVVKWTADDLKPNSPTTEKHVEDGLTVAELCEAAITLSDNTAANMVLKQIGGP +AGLTKYFRTLKDPISRLDRWETELNDWTPKERRDTTTPAAIGRDLRALTTGDALDAKDRE +RLNAWLIANKTGDARIRAGLPKTWKIGDKTGTNDAGLANDVAVVWPSGRAPIILAVYTNR +KTAGDPVDDKVIARTATILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00045B5CDB +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DB53C3 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Delftia acidovorans TaxID=80866 RepID=UPI000F4B4482 +-qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ +QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP +QALTQWLRASGDEITRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA +LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWRPQSAPLLVTGYLTE +CPADAPQRDAALAAAGKAAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0004684152 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Ncost-T10-10d TaxID=1839774 RepID=UPI000B841462 +---AVRKLRDLEREHAARLGVFGWNTVTGRSV-LHRAEERFPMCSTFKTLAVGAVLRDLD +HDGTFLSKIIHYTKQDIKRGAPVTGENLAQGMTVEDLCGAAISYSDNTAANLLMERLCGP +TSVTRFCRSIGDSVTRLDRWEPELNSAEPGRVSDTTSPRAIGKTYAQLVLGNALEAGDRK +KLTGWLLANTTGGKRLRAGLHEDWSVGDKTGTGSYGTANDVGIVWPPGQGPIVMAVLSTK +HDADSEADDLLIAHAAAVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=UPI0004657C99 +---TAADFAALEAASGGRLGVSLLDTATGQAR-GHRQDERFPMCSTFKALLSAAVLAGAD +RGQWSLDRRLPVGEGDLVPHSPVTRRHAGKDLAVRDLCRATMTTSDNAAANLLFGLIGGP +SAMTAFLRANGDTVTRSDRLEPVMNEFALGDPRDTTSPRAMAASMARFAVGEALAAQSRK +QLADWLIDNGTGDACLRAGLGPRWRVGDKTGSNGVDTRNDVAVLWPLGGTPWVLAAYLQG +ATVDSDARDAVLARVARLA---- +>[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus timonensis TaxID=1926285 RepID=UPI0009BA7AD8 +--QSEEAFKELEDEFDTKLGVYAVDTGTNQTV-SHRAEERFAYASTFKGLAAGAILQNTS +--MDDLEKDMMYSEDDLVPYSPVTENHVEDGMKLKEIMEAAIRYSDNTAGNLLLEELGGP +DGLEEQLREIGDETIEADRMEPDLNEAVPGDTKDTSTPKAFAESLQKYTLSDLLPEEKRE +LLIDWMTGNEAGDTLIRAGVPEDWEVIDKSGAGGYGSRNDIAVVWPSDQAPMVISIFSSR +DTEDADFDDAVVEKAAGLVVEQ- +>[subseq from] Beta-lactamase n=1 Tax=Afipia sp. 64-13 TaxID=1895701 RepID=A0A1Q3VZY4_9BRAD +-------LKAYERDSGGKIGLHAENVASGKTL-GWRADERFVMCSTFKASLAACVLARVD +RGVDRLDQALSYGEKDLLGYAPVARENLAKAMSLGQMCQGAVELSDNTCANLLLAHLGGP +AALTDFWRSLGDTISRLDHNEPELNNSPPGDPHDTTTPAAMAGNLKRLVLGDTLSPASRR +QLTEWMVNCKTGAKRLRGGLPRHWRIGDKTGNNGKDAVSDIAVVWPKPDTPIIVAVYTQG +GKPNAAQHEQVFAAIGRMVAE-- +>[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0012DDD487 +---FQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDVLKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Serratia liquefaciens TaxID=614 RepID=A0A484X704_SERLI +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLG--------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI0003A2A515 +----QPDFAALEQAFGARLGVYAIDTGDGREV-AYHADDRFAYASTHKVFNAAAILHRGD +----DLTRTVTIRQSDLVPNSPITEKHIGEQMSLQSVLDAALRYSDNTADNLMFREIGGP +AGLAAELRRLGDTVTHVDRIEPALNETSPGDVRDTTTPRVWAKDLRAVALDSGLPADKQA +VLTKIMRANTTGAHVIRAGVPADWQVADKTGSADYGTRNDIAVLWPPHRAPIVLTVLSDR +PQKDAKTDDKLIAQAAAAVVK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura syzygii TaxID=1427538 RepID=A0A5D0U4J9_9ACTN +-qAVAAKLRALEKARGVRVGAYAVDTGTGSLV-SYRGGERFPFASSFKAMACGAVLRKAD +SDPALMDRVIRYEKSDLSDFSPVTKKHVGTGMSVADLCHATITQSDNTAGNLVLKLIGGP +SGLTAFLRSLGDTSSRSDRAEPGLNHWRPGEQRDTTTPAAWAGDLRALTVGDALARPDRA +RLIGWLKATVTGDERIRAGLPKSWTVGDKTGTAGYGNAVDIAITWPPDRAPLVMAILTTR +PGAGDAADEKAVAETARILAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI00082ACE07 +----TGRLRALEEEYGARLGVYARNVRTGRTI-RHRADTLFPICSVFKPLAAAAVLRDLD +RNGEVLSRRIHYTADDLVDNSDRTRENLATGMTIAELCDVAIRWSDNTAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRITDTTSPRAIGRTYARLVLGDALSRADRS +RLTHWLLHNRTSGTRLRAGLPGTWTVADKTGGGAYATNNNVGIAWTEDGTPLVLAILSRT +FDEDAVQDDTLIARTAAALA--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 04169 TaxID=2203197 RepID=A0A429CW20_9PSEU +---ASADFEQLERAFGARVGVYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP +--ITELDRTVTYGKQDLVVNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP +EGLNAVFRRIGDTTSHADRIEPELNDTFPGDLRDTSTPRALAVSLRAFALGDALPEDKRK +ILVDMMRANTTGDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVVSVLTDR +PDKDAEIDNKLLADATAAAMK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNT302 TaxID=1169155 RepID=UPI00035E5643 +----VREFTELEDRFEARLGVYAVDTGTGREV-AHNEDERFAYASTFKVLAAGAVLREHS +--LSGLDQVITYSADDLVPHSPVTAKRVGTGMSLAELCDAAVRLGDNTAANLLLDELGGP +RGLDAALEEIGDDVTRMERRETQLNEWSPGSLSDTSTPRALARDLRAYVLEDALGKGERA +QLTEWLRTSATGSELIKAGVPKDWMVGHRAGAGSYGVRNDIAVVWPPDSAPIVMAIMSNG +LRRDADHDDRLIAEAASVVAD-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. TEPEL TaxID=2283801 RepID=UPI001051B2FB +---AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RGPALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRAAGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ +QLADWLIDNETGDACIRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA +GTISFEQRAAVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Kurthia sp. 3B1D TaxID=1562256 RepID=UPI000F8E5B67 +---PQQDFKELEKKYDVRLGIYVIDTATNKKI-AYHANERFAFTSTYKALAAGVLLQNAS +--LEQLETVILYTKDDLVAYSPVTELYTDTGMTLREISEAAVRYSDNTAGNLLFHAIGGP +KGFEQSLRKMGDKTTYANRFETELNTAIPGDKRDTSTAKALAIDLKKYTIDSTLSIEKRQ +LLLDWMADNKTGDALIRAGVPTDWKVVDKSGAGSYGTRNDIAVVFPPNRAPIVLAILSSR +SEQNATYDNQLIEEATRVIIK-- +>[subseq from] class A beta-lactamase n=2 Tax=Gracilibacillus thailandensis TaxID=563735 RepID=UPI00129CEF1D +----DEEFAQLEDEFEAQLGVYAIDTGKNQIV-EYNPDERFAYASTFKVLAAAILLKQNE +--IKDLEKAVTYSKDDLVTYSPVTENHVDTGMTLLEISEAAIRKSDNTAGNLLLEALGGP +EEFQALLRDLGDDVTEPERYETELNEFIPGNKSDTSTPKVLATNLKKIALEDFLPNDKRE +LLIDWMKGNATGDTLIRAGLPEEWIVGDKSGAASYGTRNDIGIVWPRDREPIIIAVMSRH +DTKDAEYDDELVAKAAGIIFD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces xiamenensis TaxID=408015 RepID=A0A0F7G0D1_9ACTN +--DPEEDFARLEEEYDVRLGVYALDTGSGEEI-GYREDERFAYASTFKALLCGAVLDEYG +--LAGMDEVIPYGEQDLVPNSPVTEENLPEGMSMSDLCDATVRYSDNTAANLLWDTVGGP +AGLQERLAGLGDDTTRMNRYEPELNEAVPGDERDTSTPRVFAANLGAYVLGEVLPEPERA +QLSEWLITNTTGDELIRAGVGEGWTVGDKTGAGGYGGRNDIAVLWPEDGEPLLLAVYSTR +EEEDAEFDNALIAEAASVAV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ICN441 TaxID=2558286 RepID=A0A4Y8MM69_9ACTN +----VREFTELEDRFEARLGVYAVDTGTGREV-AHNEDERFAYASTFKVLAAGAVLREHS +--LSGLDQVITYSADDLVPHSPVTAKRVGTGMSLAELCDAAVRLGDNTAANLLLDELGGP +RGLDAALEEIGDDVTRMERRETQLNEWSPGSLSDTSTPRALARDLRAYVLEDALGKGERA +QLTEWLRTSATGSELIKAGVPKDWMVGHRAGAGSYGVRNDIAVVWPPDSAPIVMAIMSNG +LRRDADHDDRLIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Neisseriales bacterium TaxID=2053582 RepID=A0A5C8BI81_9NEIS +---YQTKFAQLESSVNGRLGIMAINTANNQQL-EYRGNELFPFCSTGKVMVVGAILKASE +SNPQLMLRQLHYSKQDTESYAPISGQHIKDGMSVSALSQAAIAYSDNGAMNQLLQLLGGP +QAVTSYARSMGDDKFNLVRSEPQLNSAIPGDIRDTTTPTAMAASLQKLVLESSLMLPQQQ +LLQQWLKGNTTGDKRIRAGVPQGWIVGDKTGTGDYGTTNDIAVIWPPHAKPIVIVIYFTQ +DKKDAKPQDEVIAKASKIVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium japonicum TaxID=375 RepID=UPI000421F961 +------EFGAYERESGGRVGLHAENLATGVKL-SWRADERFVMCSTFKASLAACVLARID +RGEEQLAAMIRYGKADLLDYAPVAKQNLAAGMSVADMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSIGDTTSRLDHNEPELNRSLPGNPQDTTTPAAMAGNLRRLVVGEALSPASRA +LLTEWMVNCRTGANRLRGGLPASWTIGDKTGNNGKDAAGDIAVAWPKPDTPILITAYVQG +GAPNAAQIEAVFARIGRMVAE-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6D1LUC9_ECOLX +--------------------------ADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA +QLVTWLKGNTTGAASIQAGLPTSCVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ +PEQKAESRRDVLAAAAKI----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces wuyuanensis TaxID=1196353 RepID=A0A1G9W999_9ACTN +--AISRSLTELEQTHSARLGVFARNMRTGRTV-SHRAGELFPMCSVFKTLAVAAVLRDLD +REGEFLAERIRYTAKDTEEYSVITGRNLANGMTVSELCDAAIRHSDNAAANLLLRELGGP +TAVTRFCRSVGDGVTRLDRWEPRLNSAEPWRTEDTTDPRHIAQTYTRLVLGDALSLPDRQ +RLTGWLLGNTTSTERFRAGLPEDWALADKTGAGDYGTNNDVGIAWTPDGTPVVLAVLTTR +RRPDDAGDNRLVARTAELLAD-- +>[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A3A9FVI1_9BACT +-----DAFRLLEEEYDAKLGIYAMDTRTGQTV-SYREEERFAYASTHKVLAVGVLLQKMN +--VDQLEETVLIKEDDLVNYNPITEKHVNKPMTWKELSDASMRYSDNTAANHILKRIGGP +AGFKQALRDIGDDVTKPERIEPELNKVKPGETRDTSTPKALATSLQAFTMGDVLTKQKQD +LLVNWLKRNTTGDNLIRAGVPEGWEVGDKSGAASYGTRNDIAIIWPPNEDPIILAVLSSR +DEEDAEGSEELIAKATEDVM--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6ALC2_ECOLX +-----EQIKQSESQLSGRVGMIXMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKYLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVXLLGPNNKA---------- +----------------------- +>[subseq from] Class A beta-lactamase PAU-1 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A1J0HSJ3_PSEAI +--QMTAVFQQLEAKAQGRLGVHVIDTATGHEF-GYRSDELFMMLSSFKLLASALVLARAD +RGEESLTRRIRYRKQDLVPWSPVTEAYADGELTLAQLCHATITTSDNTAGNLILASYGGP +QALTQYARQLGDKITRLDRNEPDLNTRVEGGSLDTTSPRAMAMTMNKLLLGDALSPLSRN +LLRQWLLENTTGGKRLKAGTPADWTVGDKTGTNKT-DANDIGILLPPQGAPVLVTAYLAD +STASSQIKDATLAEVGRL----- +>[subseq from] Beta-lactamase n=1 Tax=Dyella sp. 4G-K06 TaxID=1927958 RepID=A0A370X0D1_9GAMM +-----NAFAALEQRYGGRLGVAVWDTENENRA-GYRADERFLMCSTFKMLLAGAVLSRVD +HGTERLDRRLVFGKDAVLAYAPITSQHAGPPMTIGELCEAAITLSDNTAANVLLTHLGGP +SVVTHLARQLGDTVTRLDHVEPELNRPSADGLSDTTTPNAMLATMHRLLLGDALSLASRQ +QLTAWMLGTVTGKKLVRAGVPADWRIAEKTGSSTR-QTNDVLVMWPPRRKPLLVTAYYDN +PAKDTQARSVVLAEAGRIIA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptosporangium nondiastaticum TaxID=35764 RepID=A0A2P7PJS2_9ACTN +--RISRRLSVLEQEHSARLGVFAHNTVTGRTV-LHGADDLFPMCSTFKTVAVAAVLRDLD +RNGEFLAKRIHYTKKEVEDYDKITDEHVANGMTVEELCAAAVSYSDNGAANLLLRELGGP +EAVTRFCRSIGDGKTRLDRWEPALNSAEPGRTTDTTTPRAIGRTYARLVLGNALAPADRK +RLTSWLLANTTSKDRLRKYLPAGWTVADKTGAGSYGTNNDVAVTWSPKGAPVVMSVLTTK +HEATAKGDDDLVAETAKILA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. RF2-non_BP3 TaxID=1637844 RepID=A0A102EY03_9BURK +--AAQAELAALEKASNGRLGVAALDTSSGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTVFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMTGGARGATGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] Beta-lactamase class A n=2 Tax=Actinophytocola oryzae TaxID=502181 RepID=A0A4R7VNJ9_9PSEU +------DFGDLEATFGARLGVYAVDTGSGRVV-EHRADERFAFCSTFKALASGALLARIP +--AADLERRVVYTSAELVANSPVSEKHVGDGMTLRELMDAAIRFSDNTAANLIFGELGGP +GGLERELRALGDEVTEMDRVETELSDAVPGDGRDTSTPRALVGDLRAYVLGDALDADDRG +LLTEFLRNNETGDALIRAGVPAGWVVGDKTGTGGYGTRNDIAVLWPPNRSPIVVAILSTR +GVKDAVTDDRLIVAATRKVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Dyella thiooxydans TaxID=445710 RepID=A0A160N3Y4_9GAMM +----ADAFAALERSHGGRLGVAVLDTGSGKRL-LHRADERFLLCSTGKLLAVAAVLARVD +QGEERLDRRIVFRREDVLDWAPVTRSHAGPPMTIEELCQAAMIVSDNTAMNLLLTTLGGP +ARLTRFVHGLGDPLTRFDRPEPSLNVPGPGGFEDTTTPLAMLDDMRQVLLGDVLSPASRG +RLLDWLRHNTTGTAQLRAGLPAGWGAGDKTGASQT-QNNDVAIVWPPGRAPLLIAAYYEG +PELTAEARKAVLAQVGAR----- +>[subseq from] Beta-lactamase n=1 Tax=Streptosporangiaceae bacterium YIM 75507 TaxID=2339229 RepID=A0A3A4AYS6_9ACTN +------RYRALERRHGARLGVYALNTATGAVV-AHRAGERFAFCSTFKTLAAAAVLDRYS +--AGGLRKRIRIAADDIDSISPVTRNHVGAGLTLRELCEAAVRHSDGTAADLLVRDLGGP +ARFNAYLRGLGDTVTRLDHYEPELNAMRPGDPRDTTTPEAIAGAYRRLILGDALPEAERA +LLTGWLKRNATGRLRVRAGVPRGWTVADKTGTGRYGRANDVAVVWPPGAPPLVIAVMTDR +PAPAAEPRDALIAQATRRVV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces antibioticus TaxID=1890 RepID=A0A1S9NIH3_STRAT +--RLGRRFHALERRYAARLGVYAHDTATGRTL-AYRANERFPLCSVFKTLAAAAVLRDLD +RDGEYLARRIRYTEEYVTAYAPITDENVAAGMTVAELCAATVSHSDNGAGNLLLRELGGP +TAITRFARSLGDPTTRLDRWEPELNTAEPWRRTDITSPRAIGRTYARLLLGGVLPRADRE +LLTGWLVANTTNTARFRAGLPADWTLADKTGGGAYGVANDVGVVWPPGRPPIVLSVLSTK +YAPEGPTDNQLVARAAALVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0008A8D5E9 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium decipiens TaxID=1430326 RepID=A0A1X2LTJ5_9MYCO +--DLADRFAELERSYQARLGVYVPATDTTAAI-AYRADERFAFCSTFKAPLVAAVLHQNP +--LSHLDTLITYTSADIRSTSPIAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGT +AAFTGYLRSLGDTVSRLDQDEPELNRDPPGDERDTTTPHAIALDFQQLVLGDALPPDKRA +LLTDWMARNTTGTKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPTGAAHVVAIMSDR +AGYEAEPSQELVADAAKCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. UNPA324 TaxID=1141174 RepID=UPI00114E3C15 +------EFESYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARID +RGEEQPTAMIPYGKDDLLEYAPAAKQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSIGDSASRLDHNEPELNRSPPGNPQDTTTPMAMASNLRRLVVGEALSPASRA +LLRDWMENCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVVWPKPETPILIAAYTQG +GTPKPAQIEAAFARIGRMAVE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Curtobacterium flaccumfaciens pv. flaccumfaciens TaxID=138532 RepID=A0A5P8YPA1_9MICO +--ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTVKVFIAAAVLDASS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP +DAVERWLRGIGDRTTSVDRVEPDLNQAVPGDRRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRDDIALVTPPGREPVVLVVMTSR +SDAGAEPSDALVAAATSAAV--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 01416 TaxID=2203196 RepID=A0A429CR28_9PSEU +-----ADFEQLERAFGARLGVYAVDTANGREV-AFRADERFAYASTHKVFSAGGVLQRTS +--IADLDRTVTYGQKDVVVNSPVTEKHVGTGLPLRAVMDATLRYSDNTGGNLLFRELGGP +EGLNAVLRGIGDTTSHADRIEPELNDTAPGDPRDTSTPRALAVSLRAFALGDALPEDKRK +ILVDMMRASTTGDQNIRAGVP-GWPVADKTGTASYGTRNDIGVVWPPNRAPIVISILTDR +SGKDAKIDNKLLAQATAAVVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004BD1009 +----VRRLRALEAEYGARVGAYARDTGTGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD +RDGEFLARRIHYTQGDVTAGGSVTERNIAGGLTMSELCSAAIAQSDNCAANLLLRELGGP +TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE +LLTRWLVSNTTSDERFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK +PDAAAPRENALVARAAEVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura fibrosa TaxID=111802 RepID=UPI00104198FC +--AVTKQIRALERSRETRIGAFAIDTGTGRYL-GNRADERFAFASTFKAIACGAVLRKAR +RDPGLMDRNVRYTKDDILPNSPETEKHVDTGMTVAELCKATITVSDNTAGNLVLKQIGGP +AGHTAFFRSLGDRVSRQDRWETDLNLWKPGEVRDTTTPRAWAGDLRALTAGDALAPADRA +QLVAWMKATETGGKRIRAGLPASWTVGDKTGTGGYGTANDIAIAYPPSGAPVIFSITTNR +LTADGTADEEAVARTATILA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111FE972 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATVKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Class A beta-lactamase n=1 Tax=Salinicola sp. L3 TaxID=2606937 RepID=A0A640W7E7_9GAMM +--DVQRKLEALEQRHGGRLGVALMNAATGEVA-SLRGDERFLFNSTIKVPIVAAVLARVE +RGEESLDRRIEVSQSDLGGWTPITEKRIGSPMTIAELGQAAVAWSDNAAANLLIESVGGP +ESVTAFLRDIGDDTTRLDRMEPALNEDHEGDERDTTTPLAMMQTLRTLLLGEALSPSMRH +QLASWMIEGKTGDARLRAGMPAGWLIGEKTGTNSVGNANDIGIAWSADRGAVIAVAYAWL +PQASKAQRDQVIAEIGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseoluteus TaxID=29306 RepID=UPI0004C1D2F5 +--NLAPRLRELEQLHSARLGVFAHDVRTGRSV-AYRADERFPMCSLFKTVAVAAVLRDLD +HDGTFLARRIRYTKAYVERYSPKTEENLAHGMTVAELCDATLRYSDNAAANLLLRELGGP +TAVTRFARSIGDPTTRLDRWEPELNSGEPWRETDTSSPRAIGRTYGRLVLGDVLAPRDRE +RLTAWMLANTTSGERFRKGLPADWLLADKTGGGRYGGNNDAGVTWPPDGGPIVLAVMTTR +FEEDAAPVNALVADAAALVAA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q6PNM4_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLISQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPN------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MP131-18 TaxID=1857892 RepID=A0A1V2RLL9_9ACTN +--SAEEEFRELEREFDARLGVYALDTGTGREV-AFQADERFAYASTFKALAVGAVLQEYG +--LDGMNEVVTYSDDDLIANSPVTENFVDTGMSLRELSAATLWYSDNTAANLLFDALGGP +EGLEAILEEHGDDVTEMDRYEPDLSEGRPGDIRDTSTPQAMAGSLRTFLLGDALDNDERQ +LLRQWMETNTTGETLISAGLPDDWTVADKSGTAGYGGRNNIAVAWPDDGNPIVLAVMSSR +DEENAERDDALIARAASAATE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-2890 TaxID=1463845 RepID=UPI0004CA6D2F +--DPEEDFARLEEEYDVRLGVYALDTGSGEEI-GYREDERFAYASTFKALLCGAVLDEYG +--LAGMDEVIPYGEQDLVPNSPVTEENLPEGMSMSDLCDATVRYSDNTAANLLWDTVGGP +AGLQERLAGLGDDTTRMNRYEPELNEAVPGDERDTSTPRVFAANLGAYVLGEVLPEPERA +QLSEWLITNTTGDELIRAGVGEGWTVGDKTGAGGYGGRNDIAVLWPEDGEPLLLAVYSTR +EEEDAEFDNALIAEAASVAF--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. cf659 TaxID=1761771 RepID=A0A1I3INL4_9BRAD +------ELEAYERESGGRIGLYAENLATGAKI-AWRADERFVMCSTFKASLAACVLARVD +RGQEQLAAMIPYGQADLLSYAPAAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRIDHNEPEVNRSPPGDPHDTTTPAAMAGNLRRLVTGEALSPASRA +QLIEWMVGCKTGANRLRGGLPARWTIGDKTGNNGKDASGDIAVVWPKSDAPILIAAYTQG +GRPSAAQIEAAFARIGRMVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacter asburiae TaxID=61645 RepID=A0A344X357_ENTAS +-----DEIKNLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ +DNQLNLNQIVNYNTRSLEFYSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +NEKEAKHEDKVIAEASRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia inohanensis TaxID=209246 RepID=UPI0012F8E4FE +-----DRLRTLEQEHTARVGLAGIDTGTGRSY-AYRGDERFGMGSTFKPLACAALLRAHP +LGTGYFDQLVRFTQDEVVTNSPIAETRVATGMTVRELCDAAITRSDNTAGNQLLKLLGGP +EALTAFLRSIGDQVTRLDRWEPLLNSNIPGDERDTTTPAALAADYRLLVVGDGLAEPERQ +QLTAWLLDNKTGGPRIRAGIPADWKTGDKTGSGDYGVANDVAVTWPAGVAPLVIAVLTTK +TEPGAQADNPLVAAAATIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces albus G TaxID=1962 RepID=BLAC_STRAL +--DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RNGEFLSRRILYTQDDVEQAGPETGKLANAQLTVEELCEVSITASDNCAANLMLRELGGP +AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK +TEQDAARDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces clavuligerus TaxID=1901 RepID=B5GPE0_STRCL +----HARLRALELEHSARLGVYGLNLATGRSV-LHRADERFPMCSLFKTIAVAAVLRDLD +RDGAFLARRIRYTQADLVEHSPVTPGRLSTGMTVSELCGAAVCRSDNSAANLLLRELGGP +SAVTRFCRSVGDRVTRLDRWEPALNSAEPWRAEDTTSPRAIGRTYTRLVLGPVLDRPDRR +RLTEWLLANTTSGDRFRAGLPGDWRLGDKTGAGEHGTNNDAGIAWKPDGTPVALAVLTTK +REPTAPSDPPLIAKTAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. FxanaA7 TaxID=1265492 RepID=UPI0005EDB7D0 +---LSRQLGELEREYSARLGVYAHDTATGRTV-AHRADERFPICSVFKTLAAGAVLRDLD +RDGEYLAKRIHYTKEYAEAYSPITATNVEAGMTVGELCSATVSHSDNGAGNLLLRELGGP +SAITRFCRSLGDRTTRLDRWEPQLNTAEPWRTTDTTTPRAIGRTYARLLLGRALRDADRE +LLTDWLIANSTNVQRFRAGLPADWTLADKTGGGTYGVANDVGVVWPPGRPPLVLSVLSTK +HDPAGPTDNPLVARAAGLVA--- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase IMI-14 n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=A0A1P8SAH3_9ENTR +-----DEIKDLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ +DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE +TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK +NEKEAMHEDKVIAEASRIAID-- +>[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis sp. AC466 TaxID=1282362 RepID=V4PEZ7_9CAUL +----AQRMLEIQKRHGGRVGVSALNTEANGSL-SISASERFAMASTFKWVLAAAILQQVD +LGKLKLAQEITYGKKDLLDYAPVTTAQVAKGMTIGDLCSAAVSLSDNTAANLLLPLIGGP +AGLTAFVRAIGDETTRFDRTEPSLNSNIDGDPQDTTTPEAMSTLLRKVYSGDVLKPDSLN +RLKEWMIATTTGKGRISAGVPAGATVAHKTGSGANGAVNDVGVVWLPGKAPVCLSIYTSG +GNLDDAGRDKIIADVTKLVFD-- +>[subseq from] Beta-lactamase n=1 Tax=Kosakonia oryziphila TaxID=1005667 RepID=A0A1C4CPP1_9ENTR +-----NVVHLQEQQLGARIGVAVLDTASSKTV-SYRGDERFPLNSTHKALLCGALLSKVD +KGELALTESTQFPRSALVEYSPITEKFVAPAINWQQLCSAAVSYSDNTAANLLAQKLGGP +AAITQYLQTLGDSVTRLDRVEPELNSAVPGDERDTTTPLAVSRTLQKLTLGTALKPGSRA +QLIQWMREDKVADALLRSTLPAGWTIADKTGAGDFGSRSIISVVWPKNSTPRIVVIYITN +TKATSKQSNAAIASLGKEIF--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A105KEM1_9BURK +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVIAEAARIAA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. SLBN-115 TaxID=1240696 RepID=A0A542HLK1_9ACTN +---VTDRLRDLEAAHGARLGVFAYNVRTGCSV-RYRADERFPVCSLFKTLAVAAVLRDLP +--EGTLDRRVFWTSTDVVENSPVTQDHVADGMTIAELSAAAIQRSDNTAGNLLLRELGGP +TAITRFARSVGDRVTRLDRWEPDLNSAEPDRVTDTTTPYAIGRTYARLVLGDALAPADRR +RLTDWMLGTITSANRFRAGLPPTWTVADKTGGGWYGANNDAGIAWTPDGAPVVLVVQLTK +PDREAAYDNELIVKTAGVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseochromogenes TaxID=68214 RepID=A0A1B1AXN0_9ACTN +-----PELSDLEQRYGARLGVYARNVRTGRTV-AYRAGERFAMCSTFKAFAAAAVLGGHG +-DCAPLDNIVHYPPRDILANSPKTEEHLATGMSVGDLCAAAIQYSDNAAGNLLLRQIGGP +DGLTRFFRSLGDRVSRLDRWEPELNTAVPGDPRDTTTPQAIGRGFERLTLGRALDDTDRA +RFIGWLKGNTTSVKRFRAGLPQGWVLGDKTGTGDYASAHDIGVAWTTRNTPVLLAVLSAK +AAKDATVDDALIAETARVLA--- +>[subseq from] Beta-lactamase n=29 Tax=Bacteria TaxID=2 RepID=B1Q1F1_ECOLX +---VTDTIQSTEDHIKGRVGFTEIDFLSGKVLsSHRREERFPMMSTFKVLLCGAILVRVD +KGLEQLERRITYNKHDLDDYSPLTSQHIADGMTVSELCNAAITTSDNTAANLLLSTIGGP +EGLTHFLRSTGDSYTRLDRHEPSLNEAKPGDERDTTTPAAMAQTLQKLLNESVLTEKSRK +KLISWMQEDKVGGPLFRSVLPAGWMIADKTGAGDHGSRGIVALLGPGGKPSRIVVLYITN +THSSMNELNEHIAGIGDSVIKNw +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces clavuligerus TaxID=1901 RepID=E2Q8M1_STRCL +----HARLRALELEHSARLGVYGLNLATGRSV-LHRADERFPMCSLFKTIAVAAVLRDLD +RDGAFLARRIRYTQADLVEHSPVTPGRLSTGMTVSELCGAAVCRSDNSAANLLLRELGGP +SAVTRFCRSVGDRVTRLDRWEPALNSAEPWRAEDTTSPRAIGRTYTRLVLGPVLDRPDRR +RLTEWLLANTTSGDRFRAGLPGDWRLGDKTGAGEHGTNNDAGIAWKPDGTPVALAVLTTK +REPTAPSDPPLIAKTAALLA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SA65_KLEPN +---------------RGRVGMIEMDLASGRTLtAWRADKRFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAAYLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +S---------------------- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A0D0I163_STEMA +---TAADFAALEKASGGRLGVTLLDTRTGKRV-GHRQDERFPMCSTIKWMLAAAALHRAD +GQPGFLDERLPMRAEDLIDHAPTTRRHVGKDLSVRDLCRTAMVTSDNPAANLLLRHLGGP +PALTAFMRSHGDAVTRSDRYEPELNRFTPGDPRDTTSPAASAVSLRRFVLGDALRPASRQ +QLADWLIDNETGDATLRAGLGKRWRVGDKTGSNGKDTRNDIGVLWPLGGTAWVLTAYLQG +ASVDSGQRDAVLARVAAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Salinicola sp. CPA62 TaxID=1949082 RepID=UPI000DA13EFB +--SVKRELEALEECHGGRVGVALMNVATGAVA-SHRGDERFLFNSTGKFFIAAAVLARVD +SGDESLDRRIEVSQSDLGGWTPITEQHLGSPMTVAQLCQAAVAWSDNAAANLLVESAGGP +ERITAFLRGIGDETTRLDRMEPELNEDHESDERDTTTPLAMMQTLRALLMDDALSSASRH +QLAAWMIAGKTGDARLRAGMPAGWLIGEKTGTNGVGNANDIGIAWPGDRGAVIAVAYTYL +PEASKTQRDDVIAEIGRLAAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. RF4-BP95 TaxID=1637845 RepID=UPI000756D83A +--AAQAELAALEKASNGRLGVAALDTASGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTVFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMTGGARGATGIAAGVPPGWRIADKTGTGGYGATTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] Beta-lactamase n=1 Tax=Nitratireductor basaltis TaxID=472175 RepID=A0A084U967_9RHIZ +--RLAEKLAATEREIGGRLGATIIDTHTGRRW-LHRADERFPMNSTFKAFAAAAVLARVD +RGEEDFKRQVPIRREDISNYAPVTERRIGGYMSLFELCEAATTMSDNTAANLITDSLGGP +EGWTQFMRSIGDDVSRLDRKEPDMTEGRPGDPRDTTTPSAITASLQTLTFGDVLQPASRE +QFRRWLLDNKVGQPLFRSVLPSDWVIGDRTGAGGHATRGIVSVIWPAQRRPVLATVYVTQ +TRGRMADRNRAIAGIGTVMVE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces clavuligerus TaxID=1901 RepID=Q59830_STRCL +-----ADLAALEREHGARLGVYALETGTGAEV-AHRADERFAFCSTFKALAAAAVLHHHP +--IRHLERRVTWTRADVDSISPVTEDHIATGLTVGQLCDAAIRHSDGTAGNLLMRDLGGP +SRLTAYLRGLGDSVSRMDQYEPELNHDPPHDPRDTTTPRAIASDYRKLVLGDALTPDRRA +LLTDWLVRNTTGGRRIRAGVPSGWRVADKTGTGNYGRANDIAVLWPPRSSPLVVAVMSDR +PGFRTPPSERLIAE--------- +>[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Achromobacter denitrificans TaxID=32002 RepID=UPI0009EC60C3 +--TFQQALAKLEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVQEYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRGLGDTVTRHDRYEPELNRPHPSEPQDTTTPRAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWRIGEKTGTYSKVGCNDAGFAQPSGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces antibioticus TaxID=1890 RepID=UPI0004C4FD4D +--RLGRRFHALERRYAARLGVYAHDTATGRTL-AYRANERFPLCSVFKTLAAAAVLRDLD +RDGEYLARRIRYTEEYVTAYAPITDENVAAGMTVAELCAATVSHSDNGAGNLLLRELGGP +TAITRFARSLGDPTTRLDRWEPELNTAEPWRRTDITSPRAIGRTYARLLLGGVLPRADRE +LLTGWLVANTTNTARFRAGLPADWTLADKTGGGAYGVANDVGVVWPPGRPPIVLSVLSTK +YAPEGPTDNQLVARAAALVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus patagoniensis TaxID=228576 RepID=UPI0009953FAB +-eTLDERLYGLEEEYDARLGLYAVDTGSGQTI-AYQSDERFAYASTHKALAVGALLQQTS +--IEDLDKKIHFTADDLVDYSPITEDNVETGMTLREISDASIRFSDNTAANLIFNEIGGP +KEFKASLRAIGDDVTEPENIETKLNDVKPGETQDTSTAKALTESLRAFALEDVLEEEQRS +LLVEWLKGNTTGDALIRAGVPDGWVVGDKTGSAAYGTRNDIGIIWPPDRAPIVLAVLSSR +DEEGAETNDELIAKATEEIVN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces humi TaxID=1428620 RepID=UPI0006289B06 +----VARLRALEREHRARLGVFAWDTGTGARL-RHRGGELFPMCSVFKTLAVAAVLRDLD +--EDVLAEVVHYDEGDVERGAPVTGRNLASGMTVAQLCAAAVSYSDNTAANLLLEQLGGP +VAVTRLSRSLGDRVTRLDRWEPELNSAEPGRGTDTTSPEAIGATYARLVLGGALDGGDRH +RLTGWLLANTTGGERIRAGLPRDWTVGDKTGTGGYGTANDVAIAWPPGRAPVVVAVLSTH +TDAAAAADSALVSAAAAVVADAf +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0006AC3E51 +---AAADFAALEKACAGCLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAMTLQRVVMGEVLRPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ICN19 TaxID=1817406 RepID=A0A5R9EDG4_9ACTN +----SRSLSELEREHTARLGVFARNMRTGRTV-SHRAGELFPMCSVFKTLAVAAVLRDLD +RKGEFLAERIRYTEKDTEEYAVITGRNLARGMTVAELCDAAVRYSDNAAANLLLRELGGP +TAVTRFCRSVGDGVTRLDRWEPHLNSAEPWRVEDTTDPRHIARTYTRLVLGDALSRPDRR +RLTGWLLNNTTSKERFRAGLPDDWTLADKTGGGEYGTNNDVGVAWTPDGTPVVLAVLTTR +QQPDDAADNRLVARTAGLLAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis alba TaxID=53437 RepID=UPI00034CC8D5 +--DVEAEFEALEAEYDTRLGVYALDTGSGEEV-EFREDERFAFASTFKSLLAGVVLSENS +--LEEMERVITYDEDALVSHSPITEENVGTGMSLLELCDATVRFSDNAAANLLLEELGGP +EGFTESLEETGDDVTTLDRYETDMSAAVPGDERDTSTPEALAGSLEAFTLGDVLPEDRRE +VLVDMLVRNTTGDAVIRAGVPEGWVVGDKTGTGGYGTRNDIAVVWPEEGDPIVLAVLSTM +EVEDAEPQDSLIAEATEVVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=UPI0005C263CF +---ASADFEQLERAFGARVGVYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP +--IAELDRTVTYGKQDLVVNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP +EGLNAVFRGIGDTTSHADRIEPELNDTFPGDLRDTSTPRALAVSLRAFALGDALPEDKRK +ILVDMMRANTTGDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVVSVLTDR +PDKDAEIDNKLLADATAAAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DCA6A1 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQKP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis dassonvillei TaxID=2014 RepID=UPI00076E3F41 +----ADEFADLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYCSTHKAFTAALVLQQNT +--PEEMEEVVTYDADDVFGHSPVTGQHVDTGLPLVEVADAAVRYSDNTAANLLFEELGGP +DGFEEAMEEMGDDVIEADRVEPGLSRWAPGDIRDTSTPRAMAGSLREFVLGDALSEDRRE +VLTRMLVDNLTGDELIRAGVPEGWEVGDKTGNGSYGTRNDIAVLWPPEGDPIVVAVMSSR +DEEDAEYDNALIAGAAEVVVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Blastococcus sp. DSM 44270 TaxID=1938745 RepID=A0A286H3N2_9ACTN +---VAPAFAELEAQFDARLGVYALETGTGRSI-EHRADERFAYASTHKALSAAAVLAAAS +--AADLDQLVPYAADDLVAHSPVTGQHAGAGLPLRDVLEAAVTRSDNTAGNLLLARLGGP +AGFQQALRDLGDATTRSDRTETSLNQGVPGDERDTSTPRALATDLAAYLLGDALDAADRE +LLTGWMRSNVTGATLVAAGVPADWGVADKSGAGGYGTRNDIAVLWPSDGPPIVLAVLSSR +GAADAGYDDALIARAATVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Methyloceanibacter caenitepidi TaxID=1384459 RepID=A0A0A8K2U7_9RHIZ +-nDLARQFAQIEKKVGGRLGVAVS--GAGLKA-ARHGGERFPMCSTFKLLAVAAVLHRVD +EGDETLSREVPVPADAILAYAPVAQQNAGGTMTVSELCEAAMVWSDNTAANLLLESLGGP +EAATAYVRSLGDTVTRIDRMEPDANVFGPGELRDTTTPEAMLGNLQKLFLGDALSPLSRD +RLTEWFVANETGKDRLRAGLPPTWRVGDRTGTGPHGTSNDVAIAWGEAGEPILIAAYLTG +SKADTAARDEALADVGRAI---- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM471 TaxID=319017 RepID=H5YCA1_9BRAD +--DAQPELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEDELAAMIPYGKADLLEYAPVARQNIAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDATSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLRRLLAGEALSATSHA +QLTEWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKDTAPILIAAYTQG +GTPSAAQIETVFARIGRMVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter sp. AG5470 TaxID=2183903 RepID=UPI001067A2D1 +-------VARLEAHLGARIGIAVVDIASGETV-SYRGNERFPLNSTYKALLCGALLSKAD +KGELSLNDTTQFSQSELVEYSPVTSKFVAPAMSWQQLCSAAVSESDNTAANQVTKKLGGP +AAITQFIASSGDSVTRLDRYEPELNSAIPGDLRDTTTPLAVSKTLQKLALGDVLTPRSRA +QLVQWMRDDKVANPLLRSVLPAGWEIGDKTGAGANGSRSIISIVWPQKNKPQIVSIYITE +TNATMAQSNDAIARIGTAIFT-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. CNZ304 TaxID=2512143 RepID=A0A4V6MH24_9ACTN +----ADEFADLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYCSTHKAFSAALVLQRNT +--PEEMEEVITYDADDVFGHSPVTEQHVDTGLPLVEVADAAVRYSDNTAANLLFDELGGP +DGFEEAMEEMGDDVIEADRVEPGLSRWAPGDTRDTSTPRAMAGSLREFVLGDALPEDRRE +VLTRMLVDNLTGDELIRAGVPEGWEVGDKTGSGNYGTRNDIAVLWPPEGDPIVLAVMSSR +EAEDAEYDNALIAGAAEVVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Kosakonia oryzendophytica TaxID=1005665 RepID=A0A1C4D0B0_9ENTR +-------VARLEAHLGARIGIAVVDIASGETV-SYRGNERFPLNSTYKALLCGALLSKAD +KGELSLNDTTQFSQSELVEYSPVTSKFVAPAMSWQQLCSAAVSESDNTAANQVTKKLGGP +AAITQFIASSGDSVTRLDRYEPELNSAIPGDLRDTTTPLAVSKTLQKLALGDVLTPRSRA +QLVQWMRDDKVANPLLRSVLPAGWEIGDKTGAGANGSRSIISIVWPQKNKPQIVSIYITE +TNATMAQSNDAIARIGTAIFT-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. TSA1 TaxID=709803 RepID=A0A2M6UKD6_9BRAD +------ELESYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGKADLLDYAPVARQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +ATLTAFWRSLGDTTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVVGEALTPASRT +QLTEWMVNCKTGANRLRGGLPAGWIVGDKTGNNGKDASGDIAVVWPRDTTPILITAYTQG +GTPNPAQIEAAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Oleiagrimonas soli TaxID=1543381 RepID=A0A099CXZ0_9GAMM +---IHTRLAALEARHGGRLGVAMLDTSSGLRV-AYRADRRFLMCSTHKVLTVAALLARVD +SGVERLQRRIVFDRDAVLDYAPITRHHVGAPMTLEALCEAAITVSDNTADNLLLETLGGP +SAVTAYARSLGDRETLLVRNEPALNLALPDDPSDTTTPQAMLADLRDLLLGDALRPASRQ +RLLGWMRQCSTGTRLLRAGLPSAWHCADKTGRGAANEINDIGLIEPPKGGPLLVAAYYAG +SIASDEARESVLADVGRLAV--- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderiales bacterium JOSHI_001 TaxID=864051 RepID=H5WTH6_9BURK +----PAALAALERRSGGRLGVWIEDSATGRVL-AQRADDRFAMCSTFKWLVCAQLLQSVD +RGEARLDQVLPFGKADLVAWSPVTERHAQGALSLAALCQATLTTSDNTAGNLLLARLGGP +AAFTAALRAQGDAVTRLDRVEPDLNRFPPGEERDSSSPRAMAAQLRRFLLGDGLAPGSRQ +QLTDWMQASTTGARRLRAGLPAGWRLATKTGTADDNHTNEVGVLWPPGRAPLVVVAFLAG +SSQPFAQREAVLARVAA------ +>[subseq from] class A beta-lactamase n=1 Tax=Ideonella azotifigens TaxID=513160 RepID=UPI0011424FCB +----SSRFQAIEKASGGHLGVFIQDTATDRRW-GHRADERFLMCSTFKLQATARVLDRVA +RGEERLDRVIAFGKADLAGYSPVTEKAVGRGMTLGELCQATMTHSDNTAANLILASYGGP +ASLTAWMRSLGDDVTRSDRTEPALNEFDATGQFDTTTPRAAAGSLRAVTLGNALPPQQRE +LLVGWMRANTTGGHRLKAGLPAGWTLGDKTGTSDD-CTNDIAVVWPTGGAPVVVTSYIGR +SRTENKLREQCLAQVAGM----- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium flaccumfaciens TaxID=2035 RepID=UPI00141AC709 +--ATTRALGALESRHDARLGLVAIDTGSGATV-THRAGERFAFASAAKVFIAATVLDDAR +--SDDLDAVVPIEQRDLLAYAPVTSQHVGSGMTVRALLDAMLRSSDNTAANLLVARVGGP +SVVQRWLRGIGDQVTQVLRVEPDLNEATPGDERDTTTPAQFAADLRTVLLGDALRPDDRQ +LLVETMAGSTTGDATIRAGVPHGWSVADKTGTGSHGVRNDVGIVTPPGGAPVVLVVMTSQ +SAADAEPDDALVATATRTAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura hibisca TaxID=68565 RepID=UPI0009FEA9E8 +---VQKELRRLEASYKARVGAFILDTGTGTSI-GHRVNETFPTASTFKAMAAAAVLDRAR +RDPGLLDRTVHWKKSDEMPNSPLTQGRGEKGMKVAEISRAAITHSDNTAGNLLLKQIGGP +AGLTRFYRSIGDRVTRSDRWEPALNEWKPGEKRDVTTPAAMGRNLQNLVLGKALVSQDRE +RLAGWMRATVTGDNRIRAGVPKGWKVGDKTGTGGYAPANDIAVAWPPSGAPVVIVVYTTR +RDPDAKVEEKLIASTTEVLV--- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. NEAU-AAG5 TaxID=2678616 RepID=UPI0012E319B9 +--AVAKRLNELERTHRARIGAWALDTGTGRVR-THRADERFPFLSTFKAIACGAVLRKAR +RDPGLLDRVIRYTEDDLVPNSPVTEKHVATGMSVADLCHAAITVSDNTAGNLVLRQIGGP +AGHTAFFRSLGDRVSRHDRWETDLNLWSPGERRDTVTPRAWGRDLRELTLGRALVPADRA +RLIGWMKAAETGGARIRAGLPPGWTVGDKTGTGGYGTANDIAIAYPPSGAPLIIVITTNR +RASGGSADEKAIAETAAILAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycetocola saprophilus TaxID=76636 RepID=UPI0009DFA082 +-----TAFAALEAEYGARLGLFLIDTGAQRTV-EYRADERFAFASTIKAHQAAAILQTRE +--IAALQEHVTFTAEQIVSYSPITEQHFEDGMLLHEVVTAALQYSDNTAANLMFDRLGGP +SGLQQLLRESGDHTINVDRIEPDLNEATPGDPRDTTTPRAHAHTLARFGISDHLPAEKRE +LLTGWMKANTTGGELIRAGVPADWVVADKTGGGYYGTRNDIAILWPPTGAPLVLAVMSSK +DAQDAEYSNALIARATTQA---- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus sp. IEGM 248 TaxID=2704615 RepID=A0A6B2K7B6_9NOCA +---LDATIDALEAQYSTRIGVTAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE +DGSTSLDKTVVIEPGDLVENSPVTAAAAGTPMTLGQIAEAALTQSDNTAGNYLLREIGGP +QAVTDLARVVGDESTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD +QLLEWMRSSKTSDKRMRAGLPTGWTAADKTGGGGFGTANDAGVAWSPDGAPLVLAILTDS +LTEGAQGNNQAIADTTAAVIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5065 TaxID=1463855 RepID=UPI0004C221B1 +-----ARLRELEERHAARLGVYAHDTATGRTV-RYRADERFPLCSVFKTLAVAAVLRDLD +RDGEFLGRNIRYTERDVTEHAPVTGEHLAAGMTAGALCSAAIRHSDNAAANLLLAELGGP +SAVTRFCRSIGDGTTRLDRREPELNSAEPWRTTDTTSPEAVGRSYARLLLGTALGRGDRA +LLTGWLLANTTGDEKLRAGLPADWAVAEKTGSGGYGTGHDVGVAWPPGRAPLVLAVLTSG +TEPDAVADSALIAGTATLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces albus subsp. albus TaxID=67257 RepID=A0A0X7JP80_9ACTN +----HPRLAALERKYDARLGVYALATGTGAAV-THRADERFAFCSTFKGLAAAAVLHRHP +--LSHVNTVVTYTEADLMQHSPVTRKHVATGMTIRQLCDAAIRFSDGTAGNLLLREIGGP +GELTAFTRGLGDTVTRMDRIEPAITEATPGDPRDTTSPRAFGTDYRKVVLGNVLAADKRA +FLRGLLERNTTGARRIRAAVPRGWTVADKTGTGDYGTLNDIAVVWPAKSPPLLISLMSSK +STKDAAYDQVLIADAAAYVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces yangpuensis TaxID=1648182 RepID=UPI000629CE8D +-----RQLRALEREYGARVGAYARDTGTGRTV-RYRADELFPMCSVFKTPAAAAVLRDLD +RDGEFLARRIHYSQGDVTSGGLVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP +TAITRFCRSLGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALAPRHRE +LLTRWLVSSTTSVDRFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPLELAVLTTM +AEPAAPRRNALVAKAAAALA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides saopaulense TaxID=1578165 RepID=UPI0008A99328 +-----NEFAALEKNFGGRIGVYALDTGSGRTV-GHRADERFLMCSTVKTFIVSAILHRRR +SVPGLLDQRIQYTQADLLEWAPITSQHVAEGMTVSELCDATIRYSDNTGANLLIAQLGGP +KETEKFVRGLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD +LLTDWLKRNTTGDQSIRAGVPSGWTVGDKTGSGFKGESNDIAVIWPPGRAPIVVAVLTVP +EDPKSTQGKPTIAAATRIALQAf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseoluteus TaxID=29306 RepID=A0A4Z1D8W8_STRGP +---LRPGLAALEKRYGARLGVYAHNTRTGATV-AYRADEPFAMCSTFKAIAAAAVLRDHG +-GRAALGEVIHYPPADILSNSEQSKAHQETGMALGDVCAAAIQYSDNTAGNLMLRRIGGP +AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPRALGRTFELLTLGRALSDGDRE +QLVGWLRGNTTSGRRFGAGLPSDWVLADKTGTGSYATANDLGVAWTGKGTPLLLCVLSTK +PAPDAPVDEALIEETARLLA--- +>[subseq from] Class A beta-lactamase n=2 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=A0A5C1ZC92_XANCT +-qTLAQRLAGIERRTRGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFVLTAAVLQRVD +RGELSLQQRLQVRASDMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP +PGLTRFLRTLCDAQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDVLRPASRQ +CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG +AKVDEAARDAALKAVAVAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD79F85 +----EAQLAALEGKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKVLAAGLVLARVD +KGKEKLDRRIRYTESDLIGGSPATKARVGDGMTVAELCAAAVTLSDNTAANLLLASFGGP +GAITAFCRSLGDETTHLDRIEPQLNYDTPEDLRDTTTAAAMLENLRRLLFTDVLSAASRS +QLAAWLITTKTGDARLRAGVAKDWLVGDKTGTSDAGNANDIAVLWPANRAPIIVTAYCEI +PEIAAGERNAIVAEIGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Variovorax soli TaxID=376815 RepID=UPI000A056F90 +--DVQARLADIEKRSGGRLGLHAIDTATGRAL-GWRSEERFAMASTFKMLLAAAVLHLHE +RTPAVLEQRLPVRQSDLIAHSPVTASHLANGITARQACEATVQVSDNAAANLLLPLVNGP +AGLTAFLRECGDAVTRLDRTEPTLNTNLPGDPRDTTTPAAMAQTMRRLLTGPVLAPASRE +QLIGWLVGATTGMARLRAGLPKDWRTGDKTGTGANGAANDVAITWPAGRAPIVMAVYLSG +SSRPSSVLDATHAQAAGVVAEAf +>[subseq from] Beta-lactamase n=1 Tax=Moraxella porci DSM 25326 TaxID=573983 RepID=A0A1T0CJX5_9GAMM +--TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP +--EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV +EQYQRILRQLGDNVTHANRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT +ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ +FTEEAKFNNKLVEDTAKQVFH-- +>[subseq from] UPI0012FE7EAE UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0012FE7EAE +-sKLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPHLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLIRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Streptoalloteichus hindustanus TaxID=2017 RepID=A0A1M5CII9_STRHI +----HDRLVELERQYEARLGVYAVHTGTCATV-AHRADERFAFCSTFKGLAAAAVLHRNP +--MSHLDTLVKYTEADLMKSSRITRQHVDTGMTIRELCDAAIRFSDGTAGNLLLRDLGGP +NRLTAYVRGLGDRVTRMDRIEPFITEATPGDPRDTSSPRALGTTYRKIVVGNALPSEKRA +FIRDLMERNVTGGDRIRAGVEKGWVVADKTGTGDYGTLNDIGLVWPPNSAPLLISIMSSK +ATKDAEYKQALLADATRYAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces caniferus TaxID=285557 RepID=A0A640SIE2_9ACTN +-----HALQKLERTHGARLGVHAVDTGTGRVV-AYRDGERFAHNSTFKALEAGAVLRKRS +--LSGMDKTIKYSKKDLVESSPVTEKHVASGMTLRALCDAAVRYSDNTAANLLFKELGGP +KKLNAVLKGLGDDVTHMERYETDLSTWDPGSTRDTTTPRAFAEDLRTFVLGDALGTAERA +QLTTWLRTNTTGDELIRAGVPKDWVVGDKTGMGSYGGRDDIAVIWRPHAAPLVVAIFSNR +TDEDADPDNKLIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces somaliensis TaxID=78355 RepID=UPI001443A9A8 +-----GRLRALERTHEARLGAFAHDTGTGRTV-AYRADERFPMASLFKTLAVAAVLRDLD +RDGEVLARRLHYTERYVREFSPVTGENLANGMTVAELCDATLTRSDNTAGNLLLRELGGP +AAVTRFCRSVGDGVTRLDRWEPELNSAEPWRVTDTTSPRAIGRTYGRLLLGNVLAAHDRE +RLTRWMLANRTSDERFRKGLPADWLLADKTGGGGYGGNNDAGVAWPPGRPPVVLAVLTTR +FAPDAAADDALVAEAAGLLAE-- +>[subseq from] Beta-lactamase n=2 Tax=Clostridium botulinum TaxID=1491 RepID=A0A140AT92_CLOBO +---YNSAFSKIESDYGVKLGVYAFDTETNKEV-TYNADKRFAYCSTFKSLISGAILQKYS +--SDQLKQVIKYSPKDVLSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP +NGFKSALNQLGDTVTEPARIEPELNVATPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKK +ILINWMSGNATGDKLIRAGAPKDWMVSDKSGTGSYGTRNDIAIVIPPNKKPIFIAILSSK +NDKDAKYDDKTISEASKIVFDYf +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia gamkensis TaxID=352869 RepID=UPI0007A3A595 +----HDRLIELERKFDARLGVYARATGTGVTV-AHRADERFAFCSTFKGLAAAAVLQRNP +--LSHLDTVVTYTRDDLLKNASVTPRYVDTGMTIRQLCDAAIRYSDGTAGNLLLRDLGGP +AELTAYARSLGDPVTRMDRIEPAITEATPGDPRDTTSPRAFGEVYHRIVLGDALPADKRD +FLRDLLERNATGAQRIRAGTPQGWRVADKTGTGDYGILNDIAVVWPPDAAPLVVAIMSSK +ATRDAAYDQALLAEAAAYVMD-- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=A0A1L3NCN3_CLOBO +--QYNSAFSQLESDYDVKLGIYAFDTEMDKEV-VYHADDRFAYCSTFKALAAGAVLKQDS +--LDELKQVVKYKKEDVLSYAPIAKDNVDKGMTIEEICNAAVRFSDNTAANLLFDHIGGP +SGFKSALNQLGDNVTQPARIEPKLNEAIPGDIRDTSTPRQLVTDLQAYTTGNILTDDKKK +ILIDWMTGNATGNTLIRAGAPDNWVVADKSGTGPYGTRNDIAIVMPPNKKPIIIAILSTH +HTKEAKYDDKLIAQASKIVFDSf +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000C6FDE9C +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGG- +-------------TFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura madurae TaxID=1993 RepID=UPI0003ACE39C +------RYAALEREHGARLGVFAVATGTGATV-AYRAGERFAFCSTFKTLAAAAVLHRHP +--LAHLEDRVTYTRADIDSISPITEDHVATGMTIRQLCDAAIRFSDGTAGNLLMRDIGGP +AGLTAYLRELGDGVSRMDDYEPELNRVRPGDPRDTTTPRAIAEDYRGLVLGTALPPDKRA +LIKDWLERSTTGAKRIRAGLPGGWKAAEKTGTGDYGRANDIAVVWPPGAAPLVVAVLSDR +PGRDARPDDALIAAATRRIV--- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. MJM2582 TaxID=1427749 RepID=UPI000506825D +-----ADFEQLERAFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP +--VAELDRTVTYGQQDLVTNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP +EGLNAVFRGIGDTTSHADRIEPELNDTFPGDLRDTSTPRALAVSLRAFALGDALPEDKRK +ILVDMMRANTTGDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVVSVLTDR +PEKDAKIDNKLLADATAAAIK-- +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter sp. Ag1 TaxID=1202448 RepID=J1GB62_9ENTR +---ITDTIQTTEDHIKGRVGFTEIDFLSGKVLgSHRHEERFPMMSTFKVLLCGAVLARVD +KGLEQLERRITYNEHDLDDYSPVTSLHLADGMSVSELCNAAITTSDNTAANLLLSTIGGP +EGLTQFVRSTGDNYTRLDRHEPSLNEALPGDERDTTTPAAMAQTLRKLLNGSLLKIASQQ +KLITWMQEDKVGGPLFRSVLPAGWMIADKTGAGEHGSRGIVALLGPRGKPSRIVILYITN +THSSMNELNEHIAGIGDSIIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DC4635 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRRLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas asiatica TaxID=2219225 RepID=UPI0010BFF684 +--TVAEAARALEAELGGRIGVVLRAPEDDPLA-VWRGDEAFPMASTFKVPLCGAVLARID +AGEEQAARILPVETAALVEWSPVTEQQAGRGMSIADLCHATITMSDNTAANLLLDTVGGP +AGLTAFLRDIGDATTRLDRTEPALNEALPEDMRDTTTPAAMADTLELLLFSELLSPEARA +QLESWMRQDAVADDLLRASLPEGWMIGDKTGAGGNGSRSIIAVLRGPAGEPWLATVYMTQ +TGGDMDKRNAAIARIGAAMI--- +>[subseq from] Class A beta-lactamase n=1 Tax=Comamonas kerstersii TaxID=225992 RepID=A0A6A1R1U0_9BURK +--SLQAHCQALEAKAQGRLGVSIVDTATGQQW-GWREDERFMMLSSFKLLASALVLHRVD +QGQESLQRRMAYPRSALIPWSPITEKHADGPLTLGELCAATITTSDNTAGNLILESYGGP +AALTAYARQLGDAVTRLDRNEPTLNRLSSDGLLDTTSPRAMAQTMHKLLVGEALSTASRQ +QLRQWLLANTTGGKRLKAGVPASWQVGDKTGTNAT-DANDIGFLIPPQGAPWIVTAYLAG +SSAEGAVKDACLADVAAWVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Nocardiopsis TaxID=2649073 RepID=UPI00135B5DAD +------DFERLEEEFDARLGVYAVDTGTGEEV-SHRPDERFAYASTHKALSAGAVLRRNS +--LEEMEEVVAYTEDDLVSHSPVTERHVETGMTLMEVADAAVRYSDNTAANLLMEELGGP +DGFEEALEAIGDDVTDPERMETELNEGVPGDTRDTSTPRAMATSLREFALGDVLPEDRRD +VFTTMLRGNTTGDTLVRAVVPEGWEVGDRTGAGGYGTRNVIAVVWPPEADPLVIAIMSSR +DREDAEYDDALVAGAAEVVVA-- +>[subseq from] Beta-lactamase n=2 Tax=Kosakonia TaxID=1330547 RepID=A0A1V0LEB7_9ENTR +---LAEVVRLQEQQLGARIGVAVVDTTSGKTA-SYRGDERFPLNSTYKALLCGTLLSKVD +NGELALTDTTQFPRSALVAYSPVTEKFVAPAINWQQLCSAAVSYSDNTAANLLAQKLGGP +ASITRYLQTLGDSVTRLDRFEPELNSAIPGDLRDTTTPLAVSRTLQKLTLGTALKPGSRA +QLIQWMREDKVADTLLRSTLPAGWTIADKTGAGDFGSRSIISVVWPENNTPRIVVIYITN +TKATLKQSNAAIASLGKAIFS-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. BJA-103 TaxID=1911175 RepID=A0A2N8MSF5_9PSEU +----RADFEQLERAFTARLGVYAVDTATGREV-AFRSEERFAYASTHKVFTAGGVLQRTP +--LADLDRTVTYSQKDLVSNSPVTEKHVATGMPLRAVIDATLRYSDNTGGNLLFRELGGP +EGLNAVLRGIGDTTSHADRIEPLLNDTAPGDLRDTSTPRALAVSLRAFALGDALPEDKRK +VLVDIMRANTTGDTNIRAGVP-GWPVADKTGTAGYGTRNDIGVVWPPDRAPIVISVLTDR +ATADAKIDNKLLAEATAAAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium sp. CBMA 295 TaxID=2606605 RepID=UPI0012DE82FD +---VDDQIAELERRHNARIGLYAVNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMVG +RGQQSLDHRVFVDPEAIVPNSPVTETHAGAEMTLAELCQAALQRSDNTAANLLLKTIDGP +AGITAFARSVGDQRTRLDRWEVELNSAIPGDPRDTSTPAALAIGYRAVLAGDALSPPQRR +QLEDWMRANQT--SSMRAGLPDGWTTADKTGSGDYGSTNDAGIAYGPDGQRLLLVMMTRS +QA-DDPKAD-------------- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea septica TaxID=472695 RepID=UPI000A11BEB0 +-------AQQEEQALKARIGIAVIDTGAESVA-SYRGNERFPLNSTHKALLCGALLSAQD +KGKLRLTERTQFDRTALVTYSPVTEKFVAPAMSWQQLCSAAISYSDNAAANLIAKKLGGP +IAVTRFFADLGDKVTRLDRSEPELNSAIPGDVRDTTTPLAVSETLRQLTLGEALTPASRA +QLLQWMRDDKVADALLRSVLPTGWSIADKTGAGEYGSRSIISVVWPQNGKPLIIAIYITQ +TEATLVQSNAAIARIGKAIF--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudorivibacter rhizosphaerae TaxID=2570323 RepID=UPI001126FCCB +---ADKPLRSIEQAIGGRLGVFAFDTASGRSL-AWRADERFAMCSTFKLLLAAAVLHRVD +QGRATLDQRLRVTAADLVNHSPVTAPRVEQGITVTEACEATVTVSDNAAANLLLPLVAGP +KGLTGWLRGVGDKVTRLDRNEPALNSNIAGDPRDTSSPRAMASTTARLFAADPLTDASRE +QLRRWIEAASTGYRRLRAGLPADWRVGDKTGTGANGSVNDVAVAWPAGRQPLVLAVYLSG +SSRPMAELEAAHAEVARQVA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 1164966.3 TaxID=1856861 RepID=A0A1A0LYT3_9MYCO +--DLTGRFDELERKYGARLGVYVPAAGAVPEI-AHRADERFAFCSTFKAPLVAAVLQHNP +--LPHLDKVVTYTAEDIRSVSPVTQQHVQTGMTIRQLCDAAIRYSDGTAANLLLAELGGP +AAFTAYLRSLGDTVSRLDQEEPELNRDVPGDERDTTTPRAIALVFQKLVLGDALPSDKRA +LLTDWMARSTTGAKRIRAGFPADWKVIDKTGSGDYGRTNDVAVVWSSNGVPHVVAVMSDR +VSYEAPSNDAIVANAATIVAS-- +>[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus pantothenticus TaxID=1473 RepID=UPI0009868B42 +-------FLLLEKEYDAKLGIYAMDTGTGKTV-SYRAEDRFAYASTHKVLAVGVLLQKMN +--VNQLEETVLIKKEDLVNYNPITEKHVNKLMTWKELSDASMRYSDNTAANYILKRIGGP +AGFKQALRDIGDDVTKPERIEPALNKVKPGETRDTSTPKALARSLQAFTMGDVLTKQKQD +LLVNWLKRNTTGDNLIRAGVPEGWEVGDKSGGASYGTRNDIAIIWPPNEDPIILAVLSSR +DEEDAEGRDELIAKATEEVM--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. MSMB0856 TaxID=1637869 RepID=UPI00075B304C +--AAQAELTALEKASNGRLGVAALDTSSGARI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTVFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMTGGARGATGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A2W4SAJ3_9PROT +---LKAAVLAAERSTGGRIGLAVHDTATGRRF-SHRGGERFPMASTFKMVMVAAILEQVD +RGRDRLDRAIPVAARDILDVSPVSKQHVGGTATVAELAEATIIYSDNTAANLLLAAVGGP +AGLTAFLRRIGDPVTRLDRIEPLMSEALPGDPRDTTSPDAIVATWEHLLLGRILSPASRD +RLTAWLVANTTGGTRLRAGLPPGWKVGDKTGTGGHGSVNDIAIVWPDRAGPLFIASFANG +GTAASDKIYSAHAMLAAAIT--- +>[subseq from] carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=UPI000DCE4C6D +----TDEINKLEKDFNGRIGVYALDTGSGKSF-SYRANERFPLCSSFKGFLAAAVLKSFQ +DNQLNIYQIVNYNTRNLEFHSPITTRYKENGMTLGDMAAAALQYSDNGATNIILERIGGP +EGMTKFMRSIGDDYFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKNLALGNILNEDEKQ +TYQTWLKGNTTGAARIRASVPTDWEVGDKTGSCGYGTANDYAIVWPKNRAPLIISVYTTK +SEKEAKHDDKVIAEASRIAIR-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A426GTB3_9BACI +--NAMEKFEQLEKEYDARLGVYAIDTGTKETV-EFHENERFAYASTFKALAAAVLLKQNP +--ISVLEETRTFTNEDIVTYSPITEDFVNKGMSLGKIAEAAMQYSDNTAGNLLFKELGGP +DGFEKALRESGDTITMADRIEPDLNEAIPGESRDTSTPKALATTLEVFGISEYLPADKQE +IFTNWLKGNTTGDSLIRAGVPESWEVGDKSGAGGYGTRNDIAIVWPPNREPIIIAIMSSR +NEENASFNDKLIAKAAKVIVQAy +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sediminis TaxID=1397368 RepID=A0A4Q7V2S8_9PSEU +--SAQEQLASLEQRFGGRLGVSATDTGNGTVI-GHRADERFLMCSTSKFLAAAAILQMRT +TQPGLLDRRIRYDASQIVRNSPITSQHVADGLPVSELCRAAITVSDNTAMNLLLGVLGGP +PALTAYVRTIGDTVTRQDRTEPGLNTTSPGDERDTSTPARMASNIRALALGDALDPQGRD +VLYGWLNANTTGGTRIKAGLPAGWGVGDKTGSGDQGEVNDVAVVRPPGRAPLIMSVFAAP +ANPDAPSDAAVVAEAGRILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. UNPF46 TaxID=1141168 RepID=UPI00114DC425 +------ELESYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDSTSRLDHNEPELNRSPPGNPQDTTTPVAMAGNLRRLVVGEALTPASRT +QLTEWMVNCKTGANRLRGGLPAGWIVGDKTGNNGKDASGDIAVVWPRDTTPILITAYTQG +GTPNPAQIEAAFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces cinnamoneus TaxID=53446 RepID=A0A2G1XJU6_STRCJ +----SRRLSSLEREHSARLGVFARNLKTGRTV-LHRADERFPMCSVFKTLAVAAVLRDLD +RDGEFLAKRVHYTEKETKDYAPRTGENLAHGMTVEELCGAAISFSDNAAANLLMRELGGP +TAVTRFCRSAGDTTTRLDRWEPALNTAEPWRTTDTTTPRAIGHTYARLVLGDVLAPRDRE +RLTGWLLANTTSAKRFRLGLPAEWTVADKTGGGDYGTNNDVGLAWTPDGTPIVLAVLTTK +HEPKPPADDPLVARAAELLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DF2817 +--DLADRFAELERRYDARLGVYVPATGTPAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora cheerisanensis TaxID=81942 RepID=UPI0009FBE1C3 +--AAAEAFRRLEERFGARLGVYVLDTGSGREV-AHRADERFAFASTSKALVGGALLRRAS +--DADLERVVTYRQQDVLAWAPVTSQHLATGMKLRDLLAASLDHSDNTAANLVMAEVGGP +AAVQQALRDLGDSTTDVSRTEPALNEAVPGDRRDTSTPRVLADDLRQYLLGDVLPPARRQ +LLTDLMLANTTGGPYIRAGVPAGWQVADRTGNGGYGTRNDLAVVWPGGGKPLVVAVLSDR +SRPDAPSNDTLLAEATEAALD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. AG855 TaxID=2183898 RepID=A0A420D4P4_9RHIZ +----TAAARQVESRLGARLGLMVVDTETNRQW-QYRSGERFAMASTFKALACAALLD--- +AGTQLLSRDIKIEAKDLLAHAPVTSKRVGTRMTAGDLCAATLSTSDNTAANLVLSTLGGP +KRVNAFLRSIGDTVTRLDRMEPALNEATPGDPRDTTTPEAMARTIGELLIGDGLASSARR +QLTRWMEANAVADDLLRAGVPRDWRIADRTGAGGHGTRGIVAVMWPPGKKPVVAAIYLTE +TEASLATRDAAIAELGRVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Saccharopolyspora spinosa TaxID=60894 RepID=UPI000C6F149C +-------FADLERRYDARLGLFAVNVHTGHVL-DHRADERFAMCSTFKTYAAAALLREHG +LDSGYFDKLIHYTEADLVAGSPITKPSAGTGMLVHELCAAAINRSDNTAANLLLAELGGP +AAIAPFARSIGDGSTRLDRWEPDLNTAIPGDERDTTTPGGIAAGHRALVVGDALGGPERD +RLTGWLFTNTTGGKRIRAGLPPTWRTGDKTGTGDYASANDVAVTWTDKGHPIVIAVLTTR +PRKDDEVNNGLHAETARIVAE-- +>[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas pictorum TaxID=86184 RepID=A0A0R0AR18_9GAMM +-----RDFAALEAESGGRLGVCLWHPASGARY-GHRMQERFPMCSTFKFLLSAAVLYRAD +RGQLALDRRVPVRAADIIDHSPVSQRHVGKDLTVRDLCRATMITSDNAAANLLLPLVGEP +AGLTAFLRAQGDAVTVCARYEPEANRFAPGDPRDTTSPAAMAANLQRFVLGDVLAPASRQ +QLADWLIDNQTGDARLRAGLPRGWRVGDKTGSNGSDATNDIAVLWPEGGSPWLLASFLQG +SALDDDGRNGILRRVGELA---- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_023 TaxID=2175657 RepID=UPI000D85BC5E +--AAERAFAALETEHHARLGVVAIDTGSGVGV-AHRADERFAFASAAKVFIAATVLDAAA +--PDDLDAVVPIGQGDVLSYAPVTGQHVGSGMTVRALLAAMVRSSDNTAANLLVARVGGP +AAVQRWLRGIGDDVTRVDRVEPDLNEAVPGDERDTTTPAQFAADLRTVLLG-ALDPDDRA +LLVGLMRGTTTGAGTIRAGVPEGWTVADKTGTGSYGVRNDVGIVTPPGRDPIVLVVMTGH +DTADAEPDDALVAAATRTAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI00040BA8E6 +-hALEARVAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD +KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGRP +PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLFRSSRA +QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDIAVAWSPNRGAIVVATYCEI +PTISADERNAVVAEVGRLVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC 01325 TaxID=2203202 RepID=A0A429BLB8_9ACTN +--ATTDRLRDLERQHGARLGVFAYNVRTRRTV-THRADELFPMCSVFKTLASAAVLRDLD +RDGEFLRRRIHYTEADLPKGSDKTREHLAEGMTVAELCEVAITYSDNGAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYGRLVLDDALNRPDRR +LLTHWLLSNTTSGKRFRAGLPKTWTVADKTGSGSYGTTNNVGVAWTPDGTPVVLSVLSTK +PAQDAAWDDALVAETAALL---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756FE11 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. TSRI0078 TaxID=1718951 RepID=A0A1Q4WQ80_9ACTN +----DPEFERLEEEFDVRLGVHALDTGTDQVV-EFQADERFAYCSTFKALAFGAVLDRTP +--VDELDRVVTFSEEDLVFHSPVTREHVADGMTLREIGDAALRHSDNTASNLLIEELGGP +EGLEEALRGIGDDVTRVDRVAPEMAQAVPGDVRDTSTPRAMTASLRAFALDDVLPEDRRG +VLVDMMRANTTGDDLIRAGAPEGWTVGDKTGACGYGTRHDIGVLWPPEGDPVVLAVMSSR +DEAGAQYDDALIARATELAV--- +>[subseq from] Beta-lactamase protein TEM-1b n=469 Tax=cellular organisms TaxID=131567 RepID=A0A1Z1V1P1_ECOLX +------------------------------------------MMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Putative Beta-lactamase n=1 Tax=Streptomyces aurantiacus JA 4570 TaxID=1286094 RepID=S3ZZU2_9ACTN +-----PRLTALERKFDARLGLYALDTATGATL-AHRADERFAFCSAFKAIAAAAVLDGNP +--LSHLDDRVRYDKGDLMKHAPITSRHVGTGMTIRQLCDAAVRYSDGTAGNLLLRDIGGP +NRLTAYARGLGDQVTRMDRFEPAITEATPGDPRDTSSPRAFGTTYREIVLGDALPKPQRA +FLRDLLERNATGAKRIRAGLPRGWTVADKTGTGDYGTLNDIAVVRPPKSPPLLVAIMSSK +ARRDAPYDEALLAEAAAYVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Agreia sp. Leaf335 TaxID=1736340 RepID=UPI0006F87911 +------AFAQLEQEFDARIGVYALDPQTRAEV-AYRADERFAYASTFKALAAGILLKTVP +--DDELDEIVSYDSSELLPNSPVTEENVADGMTLRAVAEAAVRFSDNTAGNIMLERLGGP +EGFTQALRELGDTTTSSDRVETELNSAIPGDLRDTTTPRAFALDLATLLTTDALGAAQQA +QLIDWMTGNATGAELITAGLDAGWAVADKSGAGAYGTRNDIAVLWPPSGSPIVLVVMSNR +PTEDADYDNALISRAAEATL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A106PWF4_9BURK +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderiales bacterium TaxID=1891238 RepID=A0A2W4UAM5_9BURK +--SLQTQLQQLEATAQGRLGVHIIDTATGLSH-GHRMDERFMMLSSFKLVASAFVLARVD +RGQESLERRITFAKTDLVTYSPVTERFAGTAMSLGGLCEATLTTSDNSAANFILDSFGGP +VALTRFARELGDDTTRLDRRETELNTGTAAALLDTTTPRAMALTLQKLLLGNALSPASRQ +QLQRWLVANTTGDKRLRAGLPKGWRVGEKTGTNAT-DANDIGIVWPANGAPLIITAYLAE +STASSAVKEAALAGVARLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Agreia sp. Leaf210 TaxID=1735682 RepID=A0A0Q4F185_9MICO +------AFAQLEQEFDARIGVYALDPQTRAEV-AYRADERFAYASTFKALAAGILLKTVP +--DDELDEIVSYDSSELLPNSPVTEENVADGMTLRAVAEAAVRFSDNTAGNIMLERLGGP +EGFTQALRELGDTTTSSDRVETELNSAIPGDLRDTTTPRAFALDLATLLTTDALGAAQQA +QLIDWMTGNATGAELITAGLDAGWAVADKSGAGAYGTRNDIAVLWPPSGSPIVLVVMSNR +PTEDADYDNALISRAAEATL--- +>[subseq from] Beta-lactamase n=1 Tax=Salinisphaera hydrothermalis (strain C41B8) TaxID=1304275 RepID=A0A084IPD5_SALHC +----VAGIAHIESQYGGRLGVAVLDSATGRIA-SYRGDERFPMCSTFKIFAAAAMLANVD +AGSERLNRRITYEPKDLVIYSPITRGHLTDGMTLGALARAAVRWSDNSAANLVLDSFGGP +DALNTYLRGLGDRVTRLDSREPICSQIVAGSVANTSTPVAMVGTMRSILLGDALTASSRR +RLTGWMIDGRTGDKRLRAGLPASWRVGDKTGSGDLATANDVAIAWPPHGPPLLIAVFFTG +AP-GAVDRDRPIADVGRLIG--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. 1164966.3 TaxID=1856861 RepID=UPI0009EDB326 +--DLTGRFDELERKYGARLGVYVPAAGAVPEI-AHRADERFAFCSTFKAPLVAAVLQHNP +--LPHLDKVVTYTAEDIRSVSPVTQQHVQTGMTIRQLCDAAIRYSDGTAANLLLAELGGP +AAFTAYLRSLGDTVSRLDQEEPELNRDVPGDERDTTTPRAIALVFQKLVLGDALPSDKRA +LLTDWMARSTTGAKRIRAGFPADWKVIDKTGSGDYGRTNDVAVVWSSNGVPHVVAVMSDR +VSYEAPSNDAIVANAATIVAS-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. BK022 TaxID=2512123 RepID=A0A4Q7Z736_9ACTN +------ELAALEKRYGARLGVYARNTRTGATV-AYRADEPFAMCSTFKAIAAAAVLRDHG +-GRAALGEVIHYPPADILSNSEQTRAHQQTGMALGDVCAAAIQYSDNTAGNLMLRRIGGP +AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPRALGRTFELLTLGRALGGSERE +QLVGWLRGNTTSGKRFGAGLPSDWVLADKTGTGSYASANDLGVAWTGKGTPLLLSVLSTR +PEPDAPVDEALIEETARLLA--- +>[subseq from] CBP family penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=UPI0007E195DB +---YNSAFSKIESDYGVKLGVYAFNTETNKEV-TYNADKRFAYCSTFKSLISGAILQKYS +--SDQLKQVIKYSPKDILSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP +NGFKSALNQLGDTVTEPARIEPELNVAIPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKK +ILINWMSGNATGDKLIRAGAPKDWMVSDKSGTGSYGTRNDIAIVIPPNKKPIFIAILSSK +NDKDAKYDDKTISEASKIVFDYf +>[subseq from] Class A beta-lactamase n=1 Tax=Saccharothrix syringae TaxID=103733 RepID=A0A5Q0GYV6_9PSEU +----DDEFARLEAEFGATLGVHAVDTGTGREL-SYRADHRFAHASTVKALAAGAVLLRNS +--LPELEEVVTYTRADLIAHSPVTEGRVDTGVTLREAVDAAVRFSDNTAGNLLFRELGGP +AGLAAALREVGDTTTRVDRVEPDLNEAAPGDLRDTSTPRAVTGSLRAFALGDALPGEERA +VLVDLLRRNTTGDRLIRAGAPAGWVVGDKTGTGGYGTRNDIAVAWPPDGAPVVLAVMSRR +ATEGAAHDDALIARAATVVFG-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Serratia marcescens TaxID=615 RepID=A0A649UHM4_SERMA +-------IKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVLLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTTQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNGK----------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus opacus TaxID=37919 RepID=A0A4R7QMU9_RHOOP +---LDATIDALEAQHSTRIGVTAANPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE +DGSTSLDKTVVIEPGDLVENSPVTGAAAGTPMTLAQIAEAALTQSDNTAGNYLLREIGGP +QAVTDLARDVGDGSTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD +QLLEWMRASKTSDKRMRAGLPTGWTATDKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS +LTEDAQGNNQAIADTTAAVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759D36A +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S7D5Z3_9BACT +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALL---------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces phaeochromogenes TaxID=1923 RepID=UPI0006E2B1C7 +--SLAGQLADLEREYAARLGIFAHDTATGRTV-AYRADERFPMCSVFKTLTAAAVLRDLD +RDGEFLARRIRYTKEYVTAYAPITDENVAKGLTVEELCSAAVSQSDNGAANLLLRELGGP +TAITRFARSTGDRITRLDRWEPELNSAEPWRKSDTTSPRAIGQTSARLVIGRALPAEDRE +RLTGWLIANTTNTERFRAGLPSDWTLADKTGGGSYGVANDVGVVWPPGRPPLVLSVLSTK +YAADGPQENPLVARAAALVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-6131 TaxID=1463874 RepID=UPI0004C24AA1 +-sELTNKLRALEHAHGARLGVFACDTATDGTV-TYRADELFPICSTFKTIAVAAVLRDLD +RDGAFLAKRLHYTATDVAEYAPITGLNLEAGMTVEELSAAAIRYSDNAAANLLLHELGGP +GTVTRFCRSIGDRVTRLDRWEPALNSAEPGRDTDTSSPRAIGQTYARLTIGKALDAPDRR +RLTGWLQSNTTGANRLRAGLPTDWTVAEKTGTGGYGTTNDVGIAWPVGGGSITVAVLSTK +SDPSAPADEPLIAGTARLIAD-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4V4P2S2_STEMA +----ATDFATLEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE +RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP +PAVTAFLRASGDALSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPGSRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRATVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. SAU14A_NAIMI4_5 TaxID=2072413 RepID=A0A3Q8FUG3_9GAMM +----AADFAALEKASGGRLGVTVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP +SALTAFLRAQGDTVTRNDRYEPDMNRFAKDDPRDTTSPAAMATSLARFAVGDGLSEKSRL +QLADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis alba TaxID=53437 RepID=UPI001367D4F3 +--DVEAEFEALEAEYDTRLGVYALDTGSGEEV-EFREDERFAFASTFKSLLAGVVLSENS +--LEEMERVITYDEDVLVSHSPITEENVGTGMSLLELCDATVRFSDNAAANLLLEELGGP +EGFTESLEETGDDVTTLDRYETDMSAAVPGDERDTSTPEALAGSLEAFTLGDVLPEDRRE +VLVDMLVRNTTGDAVIRAGVPEGWVVGDKTGTGGYGTRNDIAVVWPEEGDPIVLAVLSTM +EVEDAEPQDSLIAEATEVVVE-- +>[subseq from] Beta-lactamase AER-1 n=2 Tax=Bacteria TaxID=2 RepID=BLA1_AERHY +--KLIQAVQSEESALHARVGMTVFDSNTGTTW-NYRGDERFPLNSTHKTFSCAALLAKVD +GKSLSLGQSVSISKEMLVTYSPITEKSLSPEVTFGKICQAAVSYSDNTAANVVFDAIGGA +TGFNAYMRSIGDEETQLDRKEPELNEGTPGDVRDTTTPNAMVNSLRKILLGDALSASSRS +QLTQWMLDDQVAGALLRASLPSDWKIADKTGAGGYGSRSIVAVIWPPSKQPLVVGIYITQ +TKASMQASNQAIARIGVV----- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis dassonvillei TaxID=2014 RepID=A0A223QDZ3_NOCDA +----ADEFADLEEEFDARLGVYAVDTGSGEEV-EHRPDERFAYCSTHKAFSAALVLQRNT +--PEEMEEVVTYDADDVFGHSPVTEQHVDTGLPLVEVADAAVRYSDNTAANLLFDELGGP +DGFEEAMEGMGDDVIEADRVEPGLSRWAPGDTRDTSTPRAMAGSLREFVLGDALPEDRRE +VLTRMLVDNLTGDELIRAGVPEGWEVGDKTGSGNYGTRNDIAVLWPPEGDPIVLAVMSSR +DEEDAEYDNALIAGAAEVVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia hospita TaxID=169430 RepID=A0A244E0T1_9BURK +----RGRFEKLEASSGGRLGVAALNTADGSYV-SYRESERFPMCSTFKLLVVALVLKRSM +AERGLLDERVRYGDADLVANSPVTKRRVGEGMTIGELCAAALQHSDNTAANLLLTAVGGP +EVLNQFALSIGDEWFDLLRGEPEVNGSVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE +QLKAWMLGNATGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG +VTKQTLPRDEVVAEAARIVFD-- +>[subseq from] Beta-lactamase L2 n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A655MB08_STEMA +---AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDPALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRATGDTITRSDRLEPELNSFAIEDPRDTTTPAAIASTLQRLVLGNALRPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA +GTISFEQREAVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Achromobacter sp. TaxID=134375 RepID=A0A0M7D2U3_9BURK +--TFQQALAKLEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVQEYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRGLGDTVTRHDRYEPELNRPHPSEPQDTTTPRAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMSADWRIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium phyllostachyos TaxID=582672 RepID=A0A1H0AKK0_9RHIZ +----EPELEAIERRIGGRVGVAAGS-AERILV-GYRADERFPMCSTFKVLAVAATLARVE +TGSESLDRTLSYHPGDLLSYAPVTRKALEAQMSVGDLCAAAIVWSDNTAVNLLLTRLDGP +EGLTEWLRGTGDPVTRLDRDEPTLNSAIPGDPRDTTTPEAMRASLGRILLGTVLSPASRD +RLEGWMVGSQTGLKRLRAGLPKDWTMGDKTGTGTNGSINDVAILRPPGHAPVTAAVYITG +STAPMATVEAAHAEIGRLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Labedella populi TaxID=2498850 RepID=A0A3S4A357_9MICO +----DPAFTALEEEFDARLGVYALDTATGAEV-QWRAGERFAFASTYKALAAGALLDTVG +--IPGLLEVVTFTEDDLVAHSPITEEHVDEGMTLSDVADAAIRYSDNTAGNLLLEALGGP +EGFDSALEEIGDDVTVSEREEPDLNSAIPGDVRDTSTPAALAADLRAYVLGDALSEDESA +LLTDWLRLNTTGDDLIRAGVPGDWTVADKTGSASYGTRNDIAVIWPADGDPLVLAILSDR +AAEDAESDDALIARATEIAVD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID6139 TaxID=2690320 RepID=A0A6B1K111_9ACTN +-----GELADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP +AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALAAPDRE +RFVTWLKGNTTSGARFRAGLPEGWTIADKTGTGDYASANDIGVAWTTRRTPVVLAVLSTK +EGKDAPVDEALIAEAARIAAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. endophyte_N2 TaxID=2153485 RepID=UPI000FFE7B5F +-----GELADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP +AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALAAPDRE +RFVTWLKGNTTSGARFRAGLPEGWTIADKTGTGDYASANDIGVAWTTRRTPVVLAVLSTK +EGKDAPVDEALIAEAARIAAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI001376F02D +--QLQNLCQKLESTAQGRLGVCILDTQTDQQW-GWREDELFMMLSSFKLLASALVLHRVD +QGKENLQRRVTYSRNSLVPWSPITEKYADGLMTLGELCAATITTSDNTAANLILDSYGGP +NALTAYARSLGDTVTRLDRNEPSLNRQSIDGLLDTTSPRAMTKTMNKLLMGNALESSSRQ +QLREWLIANTTGGKRLKAGVPNSWLVGDKTGTNAT-DANDIGILIPPQGAPLLISVYLAE +STADNSIKDACIAEVAKWA---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia yamanashiensis TaxID=209247 RepID=UPI000AA56371 +----ETTLRGLEEKYGARLGVYAVDTKSGREV-AYRSGERFAMASTFKGLACGALLKDYP +LSSGYFDQVIRFGADEVVANSPVAEQRVETGMTVAELCQAAITVSDNTAGNLILRLQGGP +GEFTAFLRSLDDSVSRLDRWETELNTDTPGDERDTTSPAAVAADYEKLVLGNALGEPERE +MLKGWLLANTTGGQRIRAGLPQGWTVGDKTGTTERGGANDVAVTWTDKGVPVVIALLSSK +TGADTKADNALLADATRAVVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia brasiliensis TaxID=37326 RepID=UPI0004A7804E +----HDRLFELERKFDARLGVYALDTASGATI-AHRADERFAFCSTFKGLAAAAVLQRNP +--LSHLDTVIRYTEEDLTKNAAITPRHVATGMTIRDLCDAAVRYSDGTAGNLLLRDIGGP +AELTAYLRGLGDPVTRMDRIEPAITEATPGDPRDTSSPRALGTDYQRIVLGDALPEDKRA +FLRDLLERNATGAVRVRAGVPQGWKVADKTGTGEYGTLNDIAIAWPPDRAPLVLSLMSSK +ATADAEYDQALLAEAAAYVA--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=A0A2I8XJQ1_9VIBR +--KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD +NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMLNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGYGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NL15-2K TaxID=376149 RepID=A0A401MT92_9ACTN +-----AELKGLERKFDARLGVYAIDTGTGREV-AYRDGERFGYHSTFKAMAAAAVLRKYS +--LSGMNEVIKYSADDLLPNSPITEQHVETGMTLRELCDAAVRYSDNTAANLLFEALGGP +KGLEAELRKLGDDVTVMERIETGLSDWVPGETRDSTTPRAFAEDLRAYVLSDVLRKPERA +QLTKWLKTNKTGDELIRAGVPKGWVVGDKTGSGGYGGRNDIAVVWRPHADPVVMAIMSNR +SEKEDTYDNKLIAEAASVVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Erwinia sp. 9145 TaxID=1500895 RepID=UPI00054E74D8 +------KAQAIEKRLNARVGVAVIDTGSDRRW-LYNAEQRFPLNSTFKAFACGALLYQAD +AGKNDLNKTTRVTREEMIPYAPVTETLIGQSVSLDRLCAATMRTSDNVAANKIVTSIGGP +EGMTRFMREIGDSVTRLDRREPDLNEATPGDLRDTTTPAAAVASLRKLVLGNALSGASRE +KLTRWMIEDAVGGPLLRAGIPSTWRIADRTGAGGHGSRSVIAVMWPPSHAPVVVAVFITE +TTATLAARNAAIAELGAALAH-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001124196E +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAIIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0013C8788F +--AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGXPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptacidiphilus melanogenes TaxID=411235 RepID=UPI000A022A1A +----DGRLRALEQEHSARVGVFAYDSGTGRSV-TYRAGELFPMCSTWKTLGVAAVLRDLD +RDGEFLAKVIHYTRQDVTAYAPITGRNVADGMTVGDLCAAALEYSDNGAANLLLRQLGGP +QAVTRFCRSVGDRITRLDRWEPELNSAEPGRVTDTSTPRALGLTCARLTLGGALDATDRK +RLTGWLLANTTGAHRLRAGLPADWVVADKTGTGEYGTANDVGIVRPPGRGPIVMAVLSTK +HDSAAAADEPLVAGVAALLAAAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobacter sp. Root1221 TaxID=1736433 RepID=UPI000A854662 +---LNGPLSALQARAGGKLGVFAQNTGSGDFI-SFNAESRFAMCSTFKVLLAAAVLARVD +NGELSLDQTVAFSRRDLVPHAPVTSLRVAEGMSVRDLLAATLEVSDNPAANLLLPLVGGP +SGVTDFVRETGDLTTRLDRTEPELNSNLPGDLRDTTTPLAMGRTLRTLLLGRRLSVASKA +HLSAWMVASTTGKRRLRAGLPDTWRVGDKTGSGANGAFNDVAIAWPTVGAPLILAVYLSG +SGTPTDTLDAVHAVAARLVS--- +>[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A2S5VPG8_9MICO +------AFAQLEQEFDARIGVYALDPQTRAEV-AYRADERFAYASTFKALAAGILLKTVP +--DDELDEIVSYDSSELLPNSPVTEENVADGMTLRAVAEAAVRFSDNTAGNIMLERLGGP +EGFTQALRELGDTTTSSDRVETDLNSAIPGDLRDTTTPRAFALDLATLLTTDALGAAQQA +QLIDWMTGNATGAELITAGLDAGWAVADKSGAGAYGTRNDIAVLWPPSGSPIVLVVMSNR +PTEDADYDNALISRAAEATL--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces kanasensis TaxID=936756 RepID=A0A100Y9P7_9ACTN +---ADRAFRDLQRRFDARLGVHAVDTGTGREV-AFRADDRFAYASTFKALAVGVLLRER- +-GLDGLDEVIRYSRDDLVGHSPVTEGATGTGMSLRDLCAAALRYSDNTAANLLFDALGGP +DGLERKLEALGDDVIEMDRRETDLSEGRPGDVRDTSTPRAMARDLRAFLLGDALEPAERA +QLRTWMATNTTGATLVRAGVPAGWAVADKSGTAGYGGRNDIAVVWPAGGAPLVIAVMSSR +DRKGAERRDELVAQAAAAAVR-- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. KC345 TaxID=2530371 RepID=A0A4R4QZ11_9ACTN +--AVGKQLRALEKTRQVRIGAYAIDTASNRGV-GYRADERFPFLSTFKAVVCGAVLQKAR +RDPGLMDRVIRYKESDLVDHSPVTEKHVKTGMTVAELCRAAITVSDNTAANLVLKQIGGP +AGDTAFFRSLGDRRSRHDRWETALNDWKPGERRDTLVPRDWARGLRTLTTGTALAPADRT +RLIGWMKASETGADRIRAGLPEGWTAGNKTGTGGYGTANDIAVAWPPGGAPLIIVVTTNR +RAADGTEDPAAIAKAASVLVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. A14 TaxID=1194106 RepID=UPI00141F393B +---LDATIDALEAQHSTRIGVTAANPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE +DGSTSLDKTVVIEPGDLVENSPVTAAAAGTPMTLAQIAEAALTQSDNTAGNYLLREIGGP +QAVTDLARDVGDGSTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD +QLLEWMRASKTSDKRMRAGLPTGWTATDKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS +LTEDAQGNNQAIADTTAAVIK-- +>[subseq from] Beta-lactamase n=1 Tax=Mycetocola lacteus TaxID=76637 RepID=A0A3L7AI48_9MICO +----DAAFAALEAEYGARLGLFLIDTGSQRTV-EYRPDERFAFASTIKAHQAAAILQTRD +--IAALEEHVTFTADQIVSYSPITEQHIEDGMLLHEVVTAALQYSDNTAANLMFDRLGGP +SGLQQLLREIGDATINVNRIEPDLNEATPGDPRDTTTPRAHAHTLATFGVSNHLPIEKRN +LLTTWMKANTTGGELIRAGVPADWVVADKTGGGYYGTRNDIGILWPPTGAPLVLAVMSSK +DAQDAEYSNALIARATTQAL--- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinoalloteichus hymeniacidonis TaxID=340345 RepID=A0A1D8BU79_9PSEU +----HDRLLELEREFDARLGVYAIAVGTGNTV-SHRADERFAFCSAFKGLAAAAVLHRHP +--MSYLDTVVTYTEADLMASSAITEQHVATGMTIGALCDAAVRFSDGTAGNLLLRDIGGP +AELTAYTRSLGDTVTRMDRYEPTIVEATPGDPRDTTSPRAIGTDYHDIVLGAALPAEKRD +FLRDLLERNATGEQRIRAGLPAGWTVADKTGTGDYGTANDIGIVWPPDAEPIAIAIMSSK +DERDARYDNALLAAATEYVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Microbispora catharanthi TaxID=1712871 RepID=A0A5N6BCA1_9ACTN +--DVAAALRALETSFKGRIGAYAIDTATGKTI-GYRAGERFALASTFKAVAAGAVLARTT +-DRELTRKVVHWTAGEVKPNSPETGKHVKDGMTLAELCRAAIIYSDNTAGNMLLKRIGGP +QGLTRYFRTLKDPVSRLDRWETELNDWSPKEKRDTTTPAAVARDLRALTTGDALGAKDRS +RLIGWLRDNTTGDARIRAGLPTTWIVGDKTGTGGYGTANDIAVVWPADAAPIVMAIYTNR +RAADGATDDKVIAQTATVLA--- +>[subseq from] Beta-lactamase n=2 Tax=Nitrosomonas eutropha TaxID=916 RepID=Q0AH67_NITEC +------SIADIEAKVGGRVGVFAVDTGSGKVL-AHRPDERFAMCSTFKWVLAATILAQVE +QNLLSLSSHVLYGQADLLAYAPVTSMHAKEGMTVSELTRAAIVVSDNTAANLLLSKLGGP +SVVTEFVRSCGDAVTRLDRNEPTLNDNDAGDLRDTTSPRAMATLMGNVLCGNRLSSTSRD +LLLQWLRDCETGYDRLRAKLPKDWLVGDKTGTGEHGAVNDVAIAIPPGRSPILIAAFLSE +GRADRPALVAAHASISHLVAHHf +>[subseq from] Beta-lactamase n=1 Tax=Tistlia consotensis USBA 355 TaxID=560819 RepID=A0A1Y6CM52_9PROT +----AGSLTGLEQQVRGRIGVAALNVETGRRL-DNRSDERFPLCSTFKFLAAACVLRRTD +QGVERLDRRIAFTEGQVVALSPVTERRTGGAMTLRDLCEAAITASDNTAGNLLLDSFGGP +PALTDFCRSIGDSATRLDRKEPELNDVAADDPRDSTTPAAMLEDLRKILLGDVLSKLSRD +RLAAWLVASHTGRARLRAGLPGHWRVGDKTGTGLKGASADIAVAWPPGGGPILIAAYLTG +ALVPDGMRDAIYSQIGRMAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MUSC 1 TaxID=1678012 RepID=A0A1S2QFD7_9ACTN +----EAELRALEQWHGARLGVFARNLRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDHG +-DCAPPDKVIHYPPHDILPNSPRTAEHVDTGMTVADLCAAAIQYSDNAAGNLLLRQIGGP +AGLTRFFRSLGDEVSRLDRWETDLNGAVPGDLRDTTTAEALGGSFARLTLGRALSGADRS +RLVGWLKGNTTSGTRFGAGLPRDWVLADKTGTGDYGTANDVGVAWTTRGTPLLLTVLSAR +TARDAPADDALVAEAARVLA--- +>[subseq from] carbenicillin-hydrolyzing class A beta-lactamase CARB-48 n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00047175B6 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKTTRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Hyphomonadaceae bacterium BRH_c29 TaxID=1629720 RepID=A0A0F2QPS8_9RHOB +-----DSLEALERRSGGRLGVFMTDTGSGRSF-GHRADERFSMCSTFKMPLAAVILREAD +AGRLDLATAVPFTRADIVAYSPVTEPALAQGMTIAALAEAAQVQGDNTAANLLLSRIGGP +EGFTAILRSLDDTQTRLDRFETELNLGPPGELRDTTTPAAMAGLMTTLLTGDALSEPSRQ +RMIEWMVATSTGQARIRAGLPAGWRAGDKTGSGISNKYNDIAIVWPPGGAPLIVTAYYEG +PGDLRDEDQAVLAEVGRIAAD-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. S4605 TaxID=1420897 RepID=A0A317KS62_9ACTN +----HHRLTELERRYDARLGVYALATGTGATI-AHRADERFAFCSTFKGLAAAAVLHGNP +--LSHLDTVVRYTERDLMKSSAITRRHVATGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP +ARLTAYLRGLGDPVTRMDRFEPDIVTAIPGDPRDTTSPRAIGVDYQQIVLGDALPPDKRA +FLRGLLERNATGARRVRAGVPKDWTVADKTGTGDYGTLNDIALVWPPGSAPLVISIMSSK +ATRDAEYDQALIADAAAYVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas naasensis TaxID=1344951 RepID=A0A4S1WB23_9SPHN +--DFRNAILAVERASGGKLGLAVIDTGSGERF-GLHADQRFPMCSTFKLALGAAILKQVE +AKRETLARRIPVAAADIVSNSPFSEKRAGGSASVGELCHATITVSDNTAANLLLRTIGGP +AGFTRRLRAFGDPVTRLDRWETAMGEGAPGDMRDTTTPDAMADLARRLVLGGALAPTSRA +QLIAWLKATRTGLNGIRAALPEGWQAGDKTGTGGHGTDNQVAVLWRPRGAPLVVASYFTG +STLPQGQTRPLHAQVGRAIVA-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 852002-51163_SCH5372311 TaxID=1834097 RepID=A0A1A2CUC1_9MYCO +--DLTGRFDQLERKYGGRLGVYVPADGAVAEI-AHRADERFAFCSTFKAPLVAAVLQHNP +--LPHLDKVVTYTRDDIRSVSPVTQQHVQTGMTVRQLCDAAIRYSDGTAANLLLAELGGP +AAFTAYLRGLGDNVSRLDQEEPELNRDAPDDERDTTTPRAIAMVFQKLVLGDALPSDKRA +LLTDWMARSTTGAKRIRAGFPADWKVIDKTGSGDYGRTNDVAVVWSPGGVPHVVAVMSDR +ISYEAPSNDAFVANAATIVAS-- +>[subseq from] Beta-lactamase n=1 Tax=Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) TaxID=479432 RepID=UPI0006CE48A7 +---ARKELRTLEASFKGRIGAYAVDTATGKTI-TYRSGERFPLLSTFKAIAAAAVLHKAR +TDPGLLNKVVHWTTAELQEHSPVTGKHVKDGMTVARLCEAAITRSDNTAANMLLKQIGGP +AGLTAYFHTLKDPVSRLDRWETELNNWSPKEKRDTTTPASMGRDLRAVTTGDALDARDRE +RLNAWLTANKTGDARIRAGLPKTWTVGDKTGTNSYGAGNDIAVVWPGKSAPIIMSIYTNR +GAADAAVDDKVIADTAAILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756FD08 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLDAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. YR290 TaxID=1882799 RepID=A0A2C8ZK56_9BURK +---ARERFEKLEASSGGRLGVAALNTADGSYV-SYRESERFPMCSTFKLLVVALVLKRSM +AEHSLLDERVRYGDADLVANSPVTKRRAGEGMTIGELCAAALQHSDNTAANLLLTAVGGP +EVLNQFALSIGDEWFDLLRGEPEVNGSVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE +QLKAWMLGNATGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG +VTKQTLPRDEVVAEAARIVFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005E8DB94 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPRDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00084B419D +--KLNEDISLIEKQVSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATATIDERNIVVWSPVMDKRAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Salinisphaera hydrothermalis TaxID=563188 RepID=UPI000A013167 +----VAGIAHIESQYGGRLGVAVLDSATGRIA-SYRGDERFPMCSTFKIFAAAAMLANVD +AGSERLNRRITYEPKDLVIYSPITRGHLTDGMTLGALARAAVRWSDNSAANLVLDSFGGP +DALNTYLRGLGDRVTRLDSREPICSQIVAGSVANTSTPVAMVGTMRSILLGDALTASSRR +RLTGWMIDGRTGDKRLRAGLPASWRVGDKTGSGDLATANDVAIAWPPHGPPLLIAVFFTG +AP-GAVDRDRPIADVGRLIG--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0006A59B44 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACAAMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_007 TaxID=2175648 RepID=A0A2W1VBZ2_9MICO +--SVDAAFRQLERQHDARLGVMALDTGSGQRV-AYRSGERFAFASTNKVFIVAAVLAGSS +--DADLDTVVHYDRGDLLSYAPVTSRFVDSGMTVRELVDATLRFSDNTAANLLVERVGGP +DAVERYLRGIGDHTTNVDRLEPELNEATPGDPRDTTTPAQFVTDLRKVLLGTTLDTTDRT +FLRDTMLDNTTGAATVRAGVDPTWPVADKTGTGEYGVRNDIAVVYPAGRAPVVVVVMTSR +DQPDATTDDALVAAATKAAV--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobacter sp. Root1221 TaxID=1736433 RepID=A0A0Q6XVT3_9BURK +---LNGPLSALQARAGGKLGVFAQNTGSGDFI-SFNAESRFAMCSTFKVLLAAAVLARVD +NGELSLDQTVAFSRRDLVPHAPVTSLRVAEGMSVRDLLAATLEVSDNPAANLLLPLVGGP +SGVTDFVRETGDLTTRLDRTEPELNSNLPGDLRDTTTPLAMGRTLRTLLLGRRLSVASKA +HLSAWMVASTTGKRRLRAGLPDTWRVGDKTGSGANGAFNDVAIAWPTVGAPLILAVYLSG +SGTPTDTLDAVHAVAARLVS--- +>[subseq from] UPI001444C5D2 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI001444C5D2 +-----VRLMALERKFGARLGLYALDTGTGATI-AHRPDERFAFCSAFKALAAAAVLDRNP +--LSHLDTLVRYTEDDLMKHAPVTARHLDSGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +AELTAYARGLGDRVTRMDRTEPAITEATPGDPRDTSSPRAFGTSYRKILLGGALPTAKRA +FLRDLLERNTTGARRIRAGVPRGWTVADKTGTGDYGTLNDIAVLYPPKSAPLLLALMSSK +PAEDAAHQEELLAEATAYAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces angustmyceticus TaxID=285578 RepID=UPI000A3656F9 +--ALVGQLRDLEQEYSARLGVFAYDTATGRTV-DYRADERFAMCSVFKGLAAAAVLRDLD +HHGEFLARRIRYTEKYVTDYAPVTGKNVAQGMTVEDLCAAAVSQSDNGAGNLLLRELGGP +TAITRFCRSIGDGTTRLDRWEPELNTAEPWRTTDLTTPRAIGRTYARLVVGDALPAEDRS +RLTGWLVANTTNGERFRAGLPADWRLADKTGGGSYGVANDVGVVWPPGRPPLVLAVLSTK +YDPKGPTDNPLVARTAALV---- +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Streptomyces philanthi TaxID=371608 RepID=A0A367F340_9ACTN +--RVTKALAALEKRHDRRLGLYMRDTGSGRTV-AYHADERFGFCSTAKVLQAAALLEHAD +--DAELNRVITYERDDLQDYAPITRKHPDTGMSVRALLKAALQYSDNTAANLLFEQLGGP +AGLQRKMRGLGDRTSVFDRIEPDLNDTPPGTTRDTSTPRALGQDLRRFLLDDALAPDRRE +LLATWMRGNTTGDDLIRAGVPSDWKVADKTGSGTHGTQNDIAVAWRPHGAPVIIALMSRG +DDEDSASDKALLAEATKAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007BA5D09 +--AAQAELAALEKASDGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVTGSPVTESHVDTGMTISQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMTGGARSATGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] Beta-lactamase n=1 Tax=Stackebrandtia albiflava TaxID=406432 RepID=A0A562V3Q2_9ACTN +----EDRFEALEDSYDARLGVYARDTGTDEEV-TFRADERFGYASTFKALAAGAILAEYG +--VDGLDRRIRYTADDLVPHSPETGKHVDDGMTLEAICEAAVRLSDNTAANLMFDALGGP +DGLQEVLVGLGDEVTEMDRYETALNDVGPGETRDTTSPRAFATDLAAFLLGDVLHAAERE +LLTEWMTGNATGAHLVSAGVPDGWRVADKSGAGGYGGRNDIAVVWPEDGAPIVMAIMSVR +ADPDAEPSDALIADATRIATD-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylotetracoccus oryzae TaxID=1919059 RepID=UPI001117BFF6 +-------LVAIEARVGGRVGVFALDTGTGRSL-ANRPDERFALCSTFKWVLAAAILAQTD +RGRMSLGARIAYGPDDLIDHAPITKANIAKGMTLDALAAAAVTDSDNTAANLLLAKLGGP +TALTAFVRSVGDPVTRLDRNEPALNSNEAGDARDTTSPRAMVGLVNTLLCGQTLAPNSRD +LLLGWLRACKTGGDRLRAGLPRDWVVGDKTGSGRRGAINDVAIAFPPHRAPILIAAYLSG +SPARLPALAAAHADIGRWVAH-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. NAZ190054 TaxID=1747766 RepID=A0A132SCJ5_9MYCO +-----ERLDELARRHNAEIGVYAVDLATQKSV-TFRDDQPFAMCSTFKAYAAAAVLQRTQ +TGELTLQDTVPIEAGDIRPHSPVTEPRVGTSMTLAELCQAALQQSDNAAANGLLRVLGGP +QAITAFARSIGDDRTRLDRWEVELNSAVPGDPRDTSTPRALGEGYRRILTGEVLNPTARQ +QLLDWMLANQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVVYGPSGEQVVLALMTKS +ASPDAPSLRPLIGELAALVLS-- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. 60 TaxID=2586975 RepID=UPI001423D092 +-----RDFAALEKASGGRLGVTLLDARTGKRA-GHRQDERFPMCSTIKWMLAAAALHRAE +RQPGFLDERLPMRAEDLIDHAPTTRRHVGKDLTVRDLCRTTMVTSDNPAANLLLRHLGGP +PAITAFMRSHGDAVTRSDRYEPELNRFEPGDPRDTTSPSASAASLQRFVLGDALKPASRQ +QLADWLIDNETGDTTLRAGLGERWRVGDKTGSNGRDTRNDIGVLWPVGGTAWVLTAYLQG +ASVNSEQRDAVLARVAAL----- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus clausii (strain KSM-K16) TaxID=66692 RepID=Q5WLE8_BACSK +-----DVFKQLEKEYDARLGIFALDTGTGETV-SYRADARFTYASAHKPLAVAVLLQQKS +--IDELEQLITYSADDLVNYNPITENHVESGMTLRELSDASIRYSDNTAANLIFHEIGGP +EGFKEGLRAIGDTVTEPERIEPELNSVEPGEIQDTSTPEALAKSLQEFALGESLPADKQE +LLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILWPPEKEPIILAVLSSK +DEKDAEYDDELIAKATEEVINLf +>[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. SCN 68-21 TaxID=1660154 RepID=A0A1E4EPC3_9RHOB +--TIAQAARAIETELGGRVGVALRRQGDAQVT-GHRPDERFPLSSTFKAPLCGAILTLVD +AGADQLDRPIGYTSADLVDYSPVTSTHN--AMTVGALCEATITLSDNTAANLLLDRLGGP +EDFTAYLRAIGDDTTRLDRRETALNEAAPGDPRDGSTPAAMTATLDRLLFGPILSAASRD +QLEAWMRADQVADDLLRASLPQGWIIGDKTGAGGFGSRSIVAVIRPPQGGPWLAAVYLTG +NKADMPTRNRAIARIGAAIVS-- +>[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobium diazoefficiens TaxID=1355477 RepID=Q89VV4_BRADU +------ELEAYERESGGRIGLYAENLATGAKI-AWRADERFVMCSTFKASLAACVLARVD +RGQEQLAAVIPYGQADLLSYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRIDHNEPEVNRSPPGDPHDTTTPAAMAGNLRRLVTGEALSPASRA +QLTEWMVGCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWPKDTAPILIAAYTQG +GSPTAPQIEAVFARIGRMVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI000841A1FA +--AAQAELAALEKASSGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMADMLQRLLLGDTLREPQRA +QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] class A beta-lactamase n=1 Tax=Uliginosibacterium gangwonense TaxID=392736 RepID=UPI0003A1CDC2 +-qASQTKLAALEGETGGRLGIACIDTATGKAF-GYRADERFPMCSTFKWLAGAALLKQVD +EKTKRLDQRIRFSHKQLLGGSPVTQKFADTEMSLAALCEAAIADSDNTAANLIVETLGGI +PAWNAYVRTLGDQLTHLDHPEPFLNKTQMGDKRNTTTPSAMCANLKHVLLEDALSPSSRE +QLKQWMLATRTGKQRLRKDLNSGWTLANKTGTGDTGTANDIGIYWPPTGQPIVLTVYLTH +AHVPLAQQEAAIAQVGHWVRDGw +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00092B3368 +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVTRMDRTEEQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111E3CD6 +--KLNEDISLIEKQVSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATSTIDERNIVVWSPVMDKRAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRFEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSNSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSFQARDQLIAQISQLILEHy +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111D3F9F +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACAAMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007557ECE +--AAQAELAALEKASNGRLGVAALDTSNGTRV-AHRARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVVGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA +QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium basiliense TaxID=2094119 RepID=A0A3S4BGG7_9MYCO +--DFRSRFAELERQHEARLGVFVPATSTTTEI-AHRAEERFAFCSTFKGLLVAAVLHQYP +--IDHLDSMVTYSSADIRSTSPITEQHLQTGMSIRGLCDAAIRYSDGTAANLLLDQIGGA +SAFTGYLRGLGDSVSQLDQEEPELNRDPPGDERDTTTPRAIALDYQNLVLGDALPADKRA +MLTDWMARSTTGAKRIRAGFPADWKVIDKTGTGDYGRANDVAVVWSPSGAPYVVAIMTDR +ASYDAQPSDSLIADAARCVAE-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI000A3628CF +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMENNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAVIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 01376 TaxID=2203195 RepID=A0A428XVJ5_9PSEU +-----AEFEQLERAFAARLGVYAVDTANGREV-AFRADERFAYASTHKVFSAGGVLQRTS +--IADLDRTVTYGQKDVVVNSPVTEKHVGTGLPLRAVMDATLRYSDNTGGNLLFRELGGP +EGLNAVLRGIGDTTSHADRIEPELNDTAPGDPRDTSTPRALAVSLRAFALGDALPEDKRK +ILVDMMRASTTGDQNIRAGVP-GWPVADKTGTASYGTRNDIGVVWPPNRAPIVISILTDR +SAKNAKIDNKLLAQATAAVVK-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6B8HJ38_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLVD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAVWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=3 Tax=Vibrio TaxID=662 RepID=A0A0D0J707_VIBHA +--KLNEDISAIEQHIAGRIGVAIWDTQSNEHW-DYRGDERFPMMSTFKTLACATMLNQMD +TGKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTLFLRSLGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDPLIRSVLPKGWSIADRSGAGGFGSRGVTAMIWKENHKPIYVSIYITE +TDLSLQARNQVIAQISQLIVDQy +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI0005EF5489 +--KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD +NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLRTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPIYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus opacus TaxID=37919 RepID=A0A1B1K784_RHOOP +---LDATIDALEAQHSTRIGVTAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE +DGSTSLDKTVVIEPGDLVENSPVTAAAAGTPMTLAQIAEAALTQSDNTAGNYLLREIGGP +QAVTDLARDVGDGSTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASSD +QLLEWMRASKTSDKRMRAGLPTGWTATDKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS +LTEDAQGNNQAIADTTAAVIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. FJAT-44876 TaxID=2011013 RepID=UPI000BB6D903 +----EEIFGQLEEEYDARLGVYALDTGTGETV-AYRSDERFTYGSTFKPLAVGVLLQQKT +--IDDLDQLITYSSDDLVNYNPITENHVDSGMTLKELSDASIRYSDNTAANLIFNEIGGP +EGFKEGLRAIGDEVTEPERIEPELNDVEPGEIQDTSTPKALALSLQEFTLGDALPADKQE +LLIDWLKRNTTGDDLIRAGVPEGWEVGDKTGAGSHGTRNDIAIIWPPDKDPILLSVLSSK +DELDAEHDDTLIATATEEVIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinicola sp. CPA62 TaxID=1949082 RepID=UPI000DA18E60 +--DLERALAALEARHGGRVGVALMNVATGAVA-SHRGDQRFLFNSTGKFFIAAAVLARVD +SGDESLDRRIEVSQSDLGGWTPITEQHLGSPMTVAELCQAAAAWSDNAAANLLVESAGGP +QRITAFLRGIGDETTRLDRMEPELNAHHEGDERDTTTPLAMMQTIRTLLLGEALSPMSRH +QLAAWMIEGKTGDARLRAGMPTGWLIGEKTGTSGAGNANDIGIAWPGDRGAVIAVAYTYL +PDASKTQRDDVVAEIGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075ACF58 +--AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA +QLTEWMSGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. MUSC 1 TaxID=1678012 RepID=UPI0009A10F6F +----EAELRALEQWHGARLGVFARNLRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDHG +-DCAPPDKVIHYPPHDILPNSPRTAEHVDTGMTVADLCAAAIQYSDNAAGNLLLRQIGGP +AGLTRFFRSLGDEVSRLDRWETDLNGAVPGDLRDTTTAEALGGSFARLTLGRALSGADRS +RLVGWLKGNTTSGTRFGAGLPRDWVLADKTGTGDYGTANDVGVAWTTRGTPLLLTVLSAR +TARDAPADDALVAEAARVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005E64BCC +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKSPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter sp. FY-07 TaxID=1692238 RepID=UPI0007774934 +-------VARLEAHLGARIGIAVVDIASGETV-SYRGNERFPLNSTYKALLCGALLSKAD +KGELSLNDTTQFSQSELVEYSPVTSKFVAPAMSWQQLCSAAVSESDNTAANQVTKKLGGP +AAITQFIASSGDSVTRLDRYEPELNSAVPGDLRDTTTPLAVSKTLQKLALGDVLTPRSRA +QLVQWMRDDKVANPLLRSVLPAGWEIGDKTGAGANGSRSIISIVWPQKNKPQIVSIYITE +TNATMAQSNDAIARIGTAIFT-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. JCM 19035 TaxID=1460653 RepID=UPI000AD959C9 +-eETAAPFSALEDKYGARLGVYALDTGDGTTV-AYNEDDRFAYASTHKALAVGVMLQQLS +--LEELDRQIRFTEADLVTYSPITEQHLDTGMTLREISDASIRYSDNTAANLVFNEIGGP +AGFKEALRAIGDEITEPERIETELNEVEPGETRDTSSAKALAESLYAFSLGDALDEERKT +LLNDWLIHNTTGDALIRAGVPDDWIVGDKTGSASHGTRNDIGILWPPDEDPIVIAVLSSK +DQADAESDDALIAEATEAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces chrestomyceticus TaxID=68185 RepID=UPI000F61D10E +----THRLRELEREHQARIGVFALNLATGATL-LHRAHERFPMCSVFKGLAAAAVLRDLD +HDGTQLSRVIHYTEADVRKHVPITSQHVADGMSVRDLCDAAVRYSDNCAANLLLRELGGP +TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIAHTYRRLVLGDALNRPDRA +LLTDWLLRSTTSVERFRAGLPKDWKVADKSGGGSYGTSNDAGVAWTPDGTPIVLAVFTHK +PTLPTASGD-------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces angustmyceticus TaxID=285578 RepID=A0A5J4LI23_9ACTN +--ALVGQLRDLEQEYSARLGVFAYDTATGRTV-DYRADERFAMCSVFKGLAAAAVLRDLD +HHGEFLARRIRYTEKYVTDYAPVTGKNVAQGMTVEDLCAAAVSQSDNGAGNLLLRELGGP +TAITRFCRSIGDGTTRLDRWEPELNTAEPWRTTDLTTPRAIGRTYARLVVGDALPAEDRS +RLTGWLVANTTNGERFRAGLPADWRLADKTGGGSYGVANDVGVVWPPGRPPLVLAVLSTK +YDPKGPTDNPLVARTAALV---- +>[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI000671CD0B +--TFQQSLAKLEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVQGYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRGLGDTVTRHDRYELELNRPHPSEPQDTTTPRAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Comamonas kerstersii TaxID=225992 RepID=A0A0W7Z8M9_9BURK +--SLQAHCQALEAKAQGRLGVSIVDTATGQQW-GWREDERFMMLSSFKLLASALVLHRVD +QGQESLQRRMAYPRSALIPWSPITEKHADGPLTLGELCAATITTSDNTAGNLILESYGGP +AALTAYARQLGDAVTRLDRNEPTLNRPSSDGLLDTTSPRAMAQTMHKLLVGGALSTASRQ +QLRQWLLANTTGGKRLKAGVPASWQVGDKTGTNAT-DANDIGFLIPPQGAPWIVTAYLAG +SSAEGAVKDACLADVAAWVAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseofuscus TaxID=146922 RepID=A0A1X4H788_9ACTN +-----GELADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP +AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALAAPDRE +RFVTWLKGNTTSGARFRAGLPEGWTIADKTGTGDYASANDIGVAWTTRRTPVVLAVLSTK +EGKDAPVDEALIAEAARVAAR-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013D8F4AE +----AADFAALEKASGGRLGVTVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVAIAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP +SALTAFLRAQGDTVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGDGLSEKSRL +QLADWLIDNQTGDACLRAGVGKRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. AG209 TaxID=2183909 RepID=A0A397N7Z1_9GAMM +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEQDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDLVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. BK161 TaxID=887463 RepID=A0A4R7IMG1_9ACTN +--STTAEFQELEREFDARLGVYALDTGTGRTV-AHRADDRFAYASTFKALAVGAVLRKYG +--TEGLGKVVAYGRDDVVADSPVTENFAGSGMSLKGLCAATLWYSDNTAVNLLLKELGGP +DGLEKVLEGLGDDVTEMNRYEPEMSEGTPGDVRDTSTPRALAADLRAFLLGDALERDERR +LLRQWMETNVTGDTLIRAGLPDDWTVADKSGTAGYGGRNNIAVVWPEDGNPIVMAVMSTR +GKQGAERRDALIARAATVAVD-- +>[subseq from] CBP family penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=UPI0004B3C1B7 +---YNSAFSKIESDYGVKLGVYAFNTETNKEV-TYNADKRFAYCSTFKSLISGAILQKYS +--SDQLKQVIKYSPKDVLSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP +NGFKSALNQLGDTVTEPARIEPELNVATPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKK +ILIDWMSGNATGDKLIRAGAPKDWMVSDKSGTGSYGTRNDIAIVIPPNKKPIFVAILSSK +NAKDAKYDDKTISEASKIVFDYf +>[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. CNZ280 TaxID=2586994 RepID=UPI001422C038 +----HHRLTELERRYDARLGVYALATGTGATI-AHRADERFAFCSTFKGLAAAAVLHGNP +--LSHLDTVVRYTEDDLMKSSAITRRHVASGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP +ARLTAYLRGLGDPVTRMDRFEPDIVTAIPGDPRDTTSPRAIGADYQQIVLGDALPPDKRA +FLRGLLERNATGAKRVRAGVPKDWTVADKTGTGDYGTLNDIALVWPPGSAPLVISIMSSK +ATREATYDQALIADAAAYVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces rimosus subsp. paromomycinus TaxID=92743 RepID=A0A401W665_STRRY +----TRRLRELEREHQARIGVFALNLATGATL-LHRAHERFPMCSVFKGLAVAAVLRDLD +HDGTQLSRVIHYTEADVRKHVPITSQHVADGMSVRDLCDAAVRYSDNCAANLLLRELGGP +TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAVARTYRRLVLGNALNSPDRA +LLTDWLLRSTTSVERFRAGLPKDWKVADKSGGGSYGTSNDAGVAWMPDGTPIVLAVFTHK +PTQPTASGD-------------- +>[subseq from] CBP family penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=A0A6B4AS52_CLOBO +---YNSAFSKIESDYGVKLGVYAFNTETNKEV-TYNADKRFAYCSTFKSLISGAILQKYS +--SDQLKQVIKYSPKDVLSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP +NGFKSALNQLGDTVTEPARIEPELNVATPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKK +ILIDWMSGNATGDKLIRAGAPKDWMVSDKSGTGSYGTRNDIAIVIPPNKKPIFVAILSSK +NAKDAKYDDKTISEASKIVFDYf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE08E57 +---------GIEAKLGARLGLMVVDTETGRQW-QHRSRERFSMASTFKALACAALLDA-- +-GETVQSRSMTIEKQDLQDYSPVTGQRVGSQMTAAELCAVTLRTSDNTAANLALAALGGP +KRVTSFLRSIGDTVTRLDRTEPMVNEAKPGDPRDTTTPESMAQSIGDLVLGDALSADARR +QLTGWMEANEVADRLLRAGVPQDWRIADRTGAGGHGTRGIVAVMWPPQRKPVIAAIYLTE +TDASLAERDAAIAEIGRAIAA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. JCM 19045 TaxID=1460639 RepID=W7ZAL6_9BACI +-dDLTAPFSELEDQYDARLGVYALNTGNGQTI-AFNEDERFAYASTHKALAVGVMLQQLS +--IEDLDKQVTFSEAELVTYSPITEQHVETGMSLREISDASIRYSDNTAANLVFNEINGP +AGFKEALRAIGDDVTEPERMETELNDVNPGETRDTSTPKALAESLYAFSFGDALDKEKQT +LLNDWLIHNTTGDDVIRAGVPDDWVVGDKTGSASYGTRNDIGIIWPPNDEPIVIAVLSSK +DEQDGKSDDALIAEATEAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. TaxID=1883446 RepID=A0A522KC92_9GAMM +--AIAGELATLERQHGGRLGVAMLDIGSGRHA-GHRAGERFLLCSTGKLLVVGAVLARVD +RGEEQLSRRIVFGPDVILEWAPVTRKHVGAPMTVAELCHAALTISDNTAMNLLLKSVGGP +AAATRFVRSLGDDITRLDRHEPELN--VPDKGLDTTTPDAMLASMRKLLLGNVLSASSRA +QLIDWLRHNTTGETQLRAGMPASWQVGDKTGSGHT-QTNDVAIAWPPGRQPLLVTAYYEG +PADQGDMRKAVLAHVGKLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Comamonas kerstersii TaxID=225992 RepID=UPI0009851F3C +--SLQAHCQALEAKAQGRLGVSIVDTATGQQW-GWREDERFMMLSSFKLLASALVLHRVD +QGQESLQRRMAYPRSALIPWSPITEKHADGPLTLGELCAATITTSDNTAGNLILESYGGP +AALTAYARQLGDAVTRLDRNEPTLNRPSSDGLLDTTSPRAMAQTMHKLLVGGALSTASRQ +QLRQWLLANTTGGKRLKAGVPASWQVGDKTGTNAT-DANDIGFLIPPQGAPWIVTAYLAG +SSAEGAVKDACLADVAAWVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00022F2FAB +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLVLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora shandongensis TaxID=418495 RepID=A0A1H3ENW7_9PSEU +------DFAGLERRYDARLGLFAVNVHTGRSM-GYRADERFAMCSTFKTYAAGALLHRNG +LAGGYFDKLIHYTEADLVANSPVTGPNAGIGMMVNELCAAAMTRSDNTAANLMLAELGGP +PAITAFARSIGDGSTRLDRWETDLNTAIPGDERDTTTPAGIAAGYRALVLGDALGAPERD +RLTGWLFANTTGAARIRAGLPPTWRTGDKTGTGDYASGNDVAVTWTDRGQAIVIAVLTTR +PRKDDKVDNGLHADTARIVAA-- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio owensii TaxID=696485 RepID=UPI000EFB904E +--KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD +SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLIRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] class A beta-lactamase n=2 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007598C9B +--AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA +QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio rotiferianus TaxID=190895 RepID=UPI0005EF0BA7 +--KLNEDLAAIEQHIGGRIGVSVWDTQNDEHW-DYRGDERFPMMSTFKTLACATMLSDMD +SEKLDKNATAKVEERNIVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +NGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. 60-20 TaxID=1895819 RepID=A0A1M3PIU0_9RHIZ +----EAQLAALESKHPGRICVSVLDMASGKRI-EHRSGERILICSTFKTLAAALVLARVD +KGEEKFDRRVHYTESDLVDSSPATKANVGKGMTIAELCAAMMTLSDNTAGNLLLASFGGP +GALTTFCRSLGDEITHLDRLEPELNYDTPDDQRDTTTAAAMLENLRRLLFTDVLSPASRL +QLAAWLMTNRTGDTRLRAGLPKNWLAGDKTGTNGDGNANDIAVLWPSNRAPIIVTAYCEI +PAIAADERNAIIAEIGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces stelliscabiei TaxID=146820 RepID=A0A0L0L8F3_9ACTN +---LAGRLGELEREYSARLGVFAHDTATGRTV-AYRADERFPLCSVFKTLAAGAVLRDLD +RDGEYLARRIHYTEEYVKAYCPITVENVSTGMTVGELCAATVSHSDNGAGNLLLRELGGP +TAITRFCRSLGDRTTRLDRWEPELNTAEPWRTTDTTTPRAIGGTYARLLLGRALPDADRD +LLTGWLVANSTNVERFRAGLPADWTLADKTGGGSYGVANDVGVVWPPGRPPLVLSVLSTK +YDPEGPTDNPLVARAAGLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A357MY60_9GAMM +----AADFAALEKASGGRLGVTVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVAIAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVSGGP +PALTAFLRAQGDTVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGDGLSEKSRL +QLADWLIDNQTGDACLRAGVGKRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia abscessus TaxID=120957 RepID=UPI0009FC8AF2 +--DHHDRLDELEQKFDARLGLYALATGNGTTI-AHRADERFAFCSTFKTLAAAAVLHRNP +--LTHLETVVTYTEDDLLKNASITPRHVATGMTIRQLCDAAVRYSDGTAGNLLLRDIGGP +AQLTEYVRSLGDMVTRMDRIEPAITEATPGDLRDTTSPRAFGTVYQKIVLGDALPADKRD +FLRDLMERNATGAQRIRAGVPQGWTVADKTGTGDYGTLNDIAIVWPTASAPVVLAIMSGK +ATADAAYDQALIAQAAEYVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Leaf396 TaxID=1736363 RepID=A0A0Q5ZGE3_9BRAD +------ELEAYERESGGRVGLYAENLATGRKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPFGQTDLLDYAPVARQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +SALTAFWRSIGDTISRLDHDEPELNRSPPGNPQDTTTPTAMAGNLRRLVTGAALSPGSRA +QLTDWMVNCKTGANRLRGGLPASWKIGDKTGYNGKDAAGDVAVAWPKPETPILIAAYVQG +GSPTAEQIAAVFARMGRMVTE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. Root1310 TaxID=1736452 RepID=A0A0T1UP69_9ACTN +---VTDRLRDLEAGHGARLGVFAHNVRTGRSV-RYRADERFPVCSLFKTLAVAAVLRDLP +--EGTPDRRVFWTAADVVENSPVTQEHVADGMTIAELSAAAIQRSDNTAGNLLLRELGGP +AALTRFARSVGDRVTRLDRWEPELNSAEPDRITDTTSPYAIGRTYARLVLGDALAPADRR +RLTDWMLGTVTSANRFRAGLPPTWTLADKTGGGWYGANNDAGIAWTPDGTPVVLVVQLTK +PARDAAYDHELIVETAGLLA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI001124C5AB +---AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDPALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ +QLADWLIDNETGDACIRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA +GTISFEQRAAVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00045B7D1A +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIQAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas TaxID=40323 RepID=UPI0006AC5B4B +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia anaemiae TaxID=263910 RepID=UPI0012F4BE07 +------RLAGIEQQHQARLGVFAVDTGSGKTV-GLRQDERFAMMSTFKTLACAALLREHP +LATGYFDQIIHFTEADVAAGSSVTGTRIDSGMSVSELCDAAITRSDNAAGNELLKLLGGP +QALTRFLRSIGDEISRLDRWEPQLNTAIPGDERDTTTPAAIAADYRALTVGDALAAPERA +QLTAWLIATTTGGTRIRAGVPDDWRTGDKTGTGDYGSANDVAVTWPGASAPIVIAVLTTH +SSPDAKVDNALVAEAAKEA---- +>[subseq from] Beta-lactamase n=3 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A1A6X7C2_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LFA4_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=Q4W1R9_PSEAI +-------VTQEETTLQARVGVAVIDTDSGLTW-QHRGDERFPLNSTHKAFSCAAVLAQAD +RHKLNLEQAIPIERTALVTYSPVTERVPPGGLTLRELCRAAVSISDNTAANLALDAIGGA +RTFTAFMRSIGDDKTRLDRREPELNEATPGDARDTTTPIAAARSLQTLLLDGVLSAPARN +ELTQWMLGDQVADALLRAGLPRDWQIADKSGAGGHGSRSIIAVVWPPKRSAVIVAIYITQ +TAASMSASNQAVSRIGSALAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces auratus TaxID=114687 RepID=UPI000593F658 +-dELSRRLADLEQQHSARLGVFAHNTATGRSV-LHRADERFPMCSLFKTLAAAAVLRDLD +HHGEFLAKRIRYTTKDVRDYAPVTGTNLARGMTVADLCAAAISYSDNAAGNLLLRELGGP +TAITRFCRSIGDGTTRLDRCEPDLNSAEPSRITDTTSPRAIGQTYARLTLGTALTPKDRK +RLTGWLRATTTSGEKFRAGLPSDWAVADKTAGGKYGTNHDVGLTWPPSRSPIVMAVLTTK +REPDATADNPLVAKTAALLAK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) TaxID=479432 RepID=D2ARB3_STRRD +---ARKELRTLEASFKGRIGAYAVDTATGKTI-TYRSGERFPLLSTFKAIAAAAVLHKAR +TDPGLLNKVVHWTTAELQEHSPVTGKHVKDGMTVARLCEAAITRSDNTAANMLLKQIGGP +AGLTAYFHTLKDPVSRLDRWETELNNWSPKEKRDTTTPASMGRDLRAVTTGDALDARDRE +RLNAWLTANKTGDARIRAGLPKTWTVGDKTGTNSYGAGNDIAVVWPGKSAPIIMSIYTNR +GAADAAVDDKVIADTAAILA--- +>[subseq from] Beta-lactamase n=2 Tax=Mitsuokella TaxID=52225 RepID=A0A414NZB9_9FIRM +----LHELEDLEQQYQAVVGVYAIDTETGRTI-AYHEDKRFSYCSTHKALLAGAILQHFS +--LADLNEVIHYSADDILSYAPVTKNHISEGMTLGSLCEAAIRVSDNTAANLMMQKLGGP +KVFKDCLQEIGDKTTRPVRLEPELNTR--DGKKDTSTPRQLALDLQAYALGDVLTDEKKA +LLLDWMQGNATGDNLIRAGVPEGWQVADKSGSGAYGTRNDIAVIYPPDRKPIVLAILTTH +KDRDAKTDDALVAEAAGIIVK-- +>[subseq from] TEM beta-lactamase n=2 Tax=root TaxID=1 RepID=I0AXX0_9ZZZZ +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAL---------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Pannonibacter phragmitetus TaxID=121719 RepID=UPI000F45B1A6 +--QLAETVAKTESRLNARVGVVLYDTGSGWSW-ANRADERFLMNSTIKTPICGAILSAAD +AGTLTLDEELPVLQSDIVSYAPVTEKKVGQTMPLSELCLATIDMSDNTAANLLINRLGGT +EAVTEFFRSTGDTVSRLDRLEPDLNTFKSGDPRDTTSPAAMAATLEKLLLGDVLSPQSRN +QLIEWMSHGGVTGALLRKIAPEGWHIADKSGSGDQ-TRNIIAMITPPDRAPWIAVIFVSD +VKADFATRNGALQDISAAVI--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. Betaine-02u-21 TaxID=2058301 RepID=A0A2N1GL59_9GAMM +---TAADFAALEKASGGRLGVTLLDTRTGKRV-GHRQDERFPMCSTIKWMLAAAALHRAE +RQPGFLDERLPMRAEDLIDHAPTTRRHVGKDLSVRDLCRTTMVTSDNPAANLLLRHLGGP +PALTAFMRSHGDAVTRSDRYEPELNRFTLGDPRDTTSPAASAASLQRFVLGDALRPASRQ +QLADWLIDNETGDATLRAGLDKRWRVGDKTGSNGKDTRNDIGVLWPLGGTAWVLTAYLQG +ASVDGGQRDAVLARVAALA---- +>[subseq from] CBP family penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=UPI00099D6564 +---YNSAFSKIESDYGVKLGVYAFNTETNKEV-TYNADKRFAYCSTFKSLISGAILQKYS +--SDQLKQVIKYSPKDVLSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP +NGFKSALNQLGDTVTEPARIEPELNVAIPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKK +ILINWMSGNATGDKLIRAGAPKDWMVSDKSGTGSYGTRNDIAIVMPPNKKPIFVAILSSK +NAKDAKYDDKTISEASKIVFDYf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TP-A0356 TaxID=1359208 RepID=UPI0006E4288C +--SLSKEFRTFEQRYGARLGVYARNVRTGRTV-AYRAGERFAMCSTFKAFAAAAVLRDHG +-DCAPLDRVIHYPLRDILDNSQYSEDHLATGMTVGQACAAAIQYSDNTAGNLLLRQVGGP +QGLTRFFRSLGDQVSRLDRWETDLNTATPGDQQDTSTPQALGTSFERLTLGRALARTDRE +QLVTWLKGNTTSDKRFGAGLPRDWALADKTGTGSYATANDIGIAWTTRHTPLLLTVLSTK +DARDAPVDNDLIRDAAALLA--- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. WAC 06369 TaxID=2203193 RepID=A0A429G0X0_9ACTN +--EVGKRLHRLEAERNLRIGAYAIDPATGAFV-SHRADERFPYTSTFKAIACGGVLQKAR +TDPGLMERVIRYTEDDLVDWSPVTEDHVGTGMTVSALCHAAITQSDNTAGNLVMKQLGGP +AGLTRFFRSLGDGASRADRWETALNDWKPGERRDTTVPSTWAANLHKLTVGDALVPEDRE +QLIAWMKANTTGDKRIRAGLPDSWTIGDKTGTGGYGNANDIAVAWPPGRDPLVMVIMTTA +KKEDAEADDAAVAETAAILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00045B0FB3 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAALVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio owensii TaxID=696485 RepID=UPI000585BFDD +--KLNEDLSAIEDHITGRIGVSVWDTQTGEKW-DYRGDERFPMMSTFKTLACATMLKDMD +SEKLEKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces seoulensis TaxID=73044 RepID=A0A4P6U1D5_STRSO +---LRPELAELEKRYGARLGVYAHNTRTGATV-AYRADEPFAMCSTFKAIAAAAVLRDHG +-GRAALGEVIHYPPADILSNSEHSQARQETGMALGDVCAAAIQYSDNTAGNLMLRRIGGP +AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPRALGRTFELLTLGRALSHGDRE +QLVGWLRGNTTSAKRFGAGLPSDWVLADKTGTGSYASANDLGVAWTGKGTPLLLSVLSTR +PAPDAPVDEALIEETARLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Gracilibacillus lacisalsi TaxID=393087 RepID=UPI000475A6B6 +----DEEFAQLEDEFETQLGVYAIDTGENQIV-EYNPDERFAYASTFKVLAAAILLKQNE +--IKDLEEVVTYSKDDLVTYSPVTENHVDTGMTLLEISEAAIRKSDNTAGNLLLEALGGP +DEFQALIQDLGDDVTEPERYETELNEFMPGNKSDTSTPKVLATNLKKIALDDFLPNDKRE +LLMDWMKGNATGDKLIRAGLPEEWIVGDKSGAASYGTRNDIGIVWPPDREPIIIAVMSRH +DTKDAEYDDELVAKAAGVIFD-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011210319 +--KLNEDISLIEKQTSGRIGVSVWDTQTDKRW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAENLVLNEIGGP +KAVTQFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000751FC07 +--AAQAQLDALEQASNGRLGVAALDTASGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEVARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Comamonas kerstersii TaxID=225992 RepID=A0A1V0BC14_9BURK +--SLQAHCQALEAKAQGRLGVSIVDTATGQQW-GWREDERFMMLSSFKLLASALVLHRVD +QGQESLQRRMAYPRSALIPWSPITEKHADGPLTLGELCAATITTSDNTAGNLILESYGGP +AALTAYARQLGDAVTRLDRNEPTLNRPSSDGLLDTTSPRAMAQTMHKLLVGGALSTASRQ +QLRQWLLANTTGGKRLKAGVPASWQVGDKTGTNAT-DANDIGFLIPPQGAPWIVTAYLAG +SSAEGAVKDACLADVAAWVAQ-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00084A7C52 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAVIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Actinotalea fermentans TaxID=43671 RepID=A0A511Z0R8_9CELL +---VSAELAALEAELGVRIGVHALDTATGRTA-EYRADERFAYASTFKALAAGAVLAAAD +--DAALAEVVPYGPGDLVTYSPVTEAHAGVGLPLSEVLRAAVQESDNTAANLLLARLGGP +AGFAEALRALGDDVTQPVRIEPDLNAWSPGDPKDTSTPRALATDLHAYVLGDALDDADRA +LLVGWMRASTTGTALVRAGVPEGWTVADKSGQGSHGTRNDLAVVWPPGGEPIVLAVLTSR +DAPDAEPVDAAVARATAVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. UNC378MF TaxID=1502748 RepID=A0A1G5UD01_9RHIZ +----EPDWGAIERRLDGRLGISAAT--EDRVLsAYRADERFPMCSTFKVLAVAAVLARVD +AGRETLDRIVAYGPGDLLSYAPVTRAALEAGMRVSDLCSAAIVWSDNTAANLLLASLGGP +EALTAWLRGTGDPVTRLDRTEPTLNTALPGDPRDTTTPGAMRTTLGRILLGTVLSSASRG +RLDAWMGACETGRKRLRAGLPSDWIAGDKTGSGDNGSVNDVAILRPPGHAPVLVAVYLTG +STASAENIAAAYAEIGRIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 1222.2 TaxID=1938833 RepID=A0A286EXY6_9ACTN +---LAGRLGELEREYSARLGVFAHDTATGRTV-AYRADERFPLCSVFKTLAAGAVLRDLD +RDGEYLARRIHYTEEYVKAYCPITVENVSTGMTVGELCAATVSHSDNGAGNLLLRELGGP +TAITRFCRSLGDRTTRLDRWEPELNTAEPWRTTDTTTPRAIGGTYARLLLGRALPDADRD +LLTGWLVANSTNVERFRAGLPADWTLADKTGGGSYGVANDVGVVWPPGRPPLVLSVLSTK +YDPEGPTDNPLVARAAGLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI00130DD8C1 +--DIDVRLAALERKTGGRLGVSVLDTETNIGF-DYRETERFPMLSTFKTLAAACVLARID +QNEDALERRIRFSKDDLVTYSPVTEKFVDGEMTLSAICAAAITLSDNTAGNLLLAQVGGP +QGLTAWLRSIGDAVTRLDRTEPTLNESLKGDARDTTTPSAMRETITSLIAGDALSPSSRD +HLLGWLVANKTGDQRLRAGLPGDGLIGEKTGTTDKGGACDVGLFQPARRQPIFISAYVAE +ATVPVKELNPVFSEIGRMVTE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SCA2-2 TaxID=1563677 RepID=A0A4Q6V4P0_9ACTN +--DAERRLARLERESGIRLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +QNGEFLSRRIFYTRDDVEQGAPETGKNLANGMTVEELCKVSITASDNCAANLTLRELGGP +TAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPEDWVLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLSAQ +TEQDAVRDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea pusilla TaxID=46177 RepID=A0A1H7ZLV3_9ACTN +--SARKELRALEKTYQARIGAYALDTGTGKTV-AYRAGERFPLLSTFKALAAAAVLHKAR +TDPGLMNRVVTWTQDEVKPNSPETEKHVKDGMTVAELCRAAITKSDNTAGNMLLKQLGGP +SGLTRYLRALKDPVSRLDRWETELNLWSPKERRDTTTPAALARDLRALTVGDALAPEDRE +RLNGWLRANETGDTRIRAGLPPTWTVGDKTGTGTYAANNDVAIVWPADAAPVIIAIYTNR +DTAGAAREDEIVSRTATILA--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis lurida NRRL 2430 TaxID=1460371 RepID=A0A2P2FN55_9PSEU +-----ADFEQLERAYRARLGVYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP +--VADLDRTVTYERKDLVVNSPVTEKHVATGMPLRAVMDATLRYSDNTGGNLLFRELGGP +AGLNAVLRAIGDTTSHADRIEPELNDTAPGDTRDTSTPRALAVSLRAFALGDALPEDKRK +ILVDMMRASTTGDQNIRAGVP-GWPVADKTGTASYGTRNDIGVVWPPGRAPIVVSVLTDR +SEKDAGIDNKLLADATAAAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Salibacterium halotolerans TaxID=1884432 RepID=A0A1I5SE59_9BACI +----DEKFAQLENEFDAQLGVYAMDTGTNQIV-EYRPDERFAYSSTFKPLAAAILLKQNN +--IEYLEKVVTYTSDDLVAHSPVTKKHVDTGMSLLEISEAAIRKSDNTAGNLLLEAIGGP +VKFEQALRDIGDDTTQSERYEIELNKFTPRNKRDTSTPRAMAANLNKVALSDFLSNNKRE +LLIDWMTGNEAGDPLIRAGAPEKWKVIDKSGAGTYGTRNDIAVVWPPNKEPIVIAIMSRH +DTKNAEYDDALIAKAAEIS---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Tu 2975 TaxID=2676871 RepID=UPI001357D003 +----HERLAELERTYDARLGVYALATGTGEVI-AHRADERFAFCSTFKGLAAAAVLDRNP +--LSHLDTLVRYTEADLLENAAVTPRHVSTGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP +AELTAYARGLGDTVTRMDRIEPLITEATPGDPRDTTSPRAFGSDYRKIVLGDALPPAKRA +FLRDLLERNATGAARVRAGVPKGWTVADKTGTGSYGTLNDIAVVWPPKSAPLVISIMSSK +ATEDAAYDQTLIAEAATYAV--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LFB0_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFTDWLIDNQTGDACLRAGLAKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075E8A81 +---AQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. P1-11 TaxID=2024616 RepID=A0A5A7ZYL1_9RHIZ +----EPDWGAIERRLDGRLGISAAT-ADRVL-sAYRADERFPMCSTFKVLAVAAVLARVD +AGRETLDRIVAYGPGDLLSYAPVTRTALEAGMRVSDLCSAAIVWSDNTAANLLLASLGGP +EALTAWLRGTGDPVTRLDRTEPTLNTALPGDPRDTTTPGAMRTTLGRILLGTVLSSASRG +RLDAWMGACETGRKRLRAGLPSDWIAGDKTGSGDNGSVNDVAILRPPGHAPVLVAVYLTG +STASAETIAAAYAEIGRIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia sp. NRRL S-836 TaxID=1519492 RepID=A0A0M8WJV0_9NOCA +----TGRLRDLEQQHGARLGVFASDTGSGRTV-LYRSNERFPICSVFKTLVAGAVLRRDQ +-DGALLDKVLRYTQAEVDKYGPITGKNLANGMTVRALCEATITYSDNAAANLLLRELGGP +SAVTRFCRSIGDPVTRLDRWEPELNSAEPWQECDTTSPRAIGQSYARLTVGHALERPDAR +QLTDWLLANTTGANRLRAGLPGEWRLGDKTGTGSYGTTNDVGITWPPGRAPIVVAVLATK +PAPKAGADEPLVAKAAALVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNR698 TaxID=1206101 RepID=UPI000483DF8A +----VREFTELEDRFEARLGVYAVDTGTGQEV-AHNEDERFAYASTFKVLAAGAVLREHS +--LSGLDQVITYSADELVPHSPVTAKRVATGMTLAELCDAAVRLGDNTAANLLLDELGGP +RGLDAALEEIGDDVTRMERRETQLNEWSPGSLSDTSTPRALARDLRAYVLEDALGKGERA +QLTEWLRTSATGSELIKAGVPKDWMVGHRAGAGGYGVRNDIAVVWPPDSAPIVMAIMSNG +LRRDADHDDRLIAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=UPI0004107226 +-------FEAYERETGGRIGLYAEDVATGAKV-TWRTDERFVMCSTFKASLAACVLARID +RGEDQLENVVRYRAADLLHHAPAARQNLASGMSVADMCKAAVELSDNTCANLLLARIGGP +AALTAFWRDTGDTVSRLDHYELELNRSPPGDPHDTTTPAAMAGNLRHFVLGEVLSPASRE +RLTDWMLNCKTGNNRLRNGLPKDWKIGDKTGNNGKDAAGDIAVVWPRKGGPVLISAYTQG +GSPTAQQLEAVFAAIGQMIGRRf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q3V781_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMAASLARFAVGNGLQPASRQ +QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces auratus AGR0001 TaxID=1160718 RepID=J2K7Y9_9ACTN +-dELSRRLADLEQQHSARLGVFAHNTATGRSV-LHRADERFPMCSLFKTLAAAAVLRDLD +HHGEFLAKRIRYTTKDVRDYAPVTGTNLARGMTVADLCAAAISYSDNAAGNLLLRELGGP +TAITRFCRSIGDGTTRLDRCEPDLNSAEPSRITDTTSPRAIGQTYARLTLGTALTPKDRK +RLTGWLRATTTSGEKFRAGLPSDWAVADKTAGGKYGTNHDVGLTWPPSRSPIVMAVLTTK +REPDATADNPLVAKTAALLAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Alcanivorax sp. Alg238-V104 TaxID=2305993 RepID=UPI0013D564B4 +--ALGHRCQEWERRHGGRIGVAVWNLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD +QGQESLDRRLLVSRKDLVGWSPVTEKRTGEGMTVAELCEAAVAWSDNGAANLLVKGFGGP +GALTEFLRESGDPVTRLDRLEPELNGYGPDGEYDTTSPAAMLETLHRLLFGEVLSAHGRA +QLAAWMIANKTGDRRLRAGFPANWLVADKTGTSGLGYSNDIGVAWSPARGAVLVTVYCEM +PKAEAEARDRIIAEVAEMV---- +>[subseq from] Uncharacterized protein n=1 Tax=Caulobacterales bacterium 32-69-10 TaxID=1970503 RepID=A0A258FCR5_9PROT +--EAEPQIAALEARYGGRLGFMALDTGSGRRI-AYRADERFNTASTFKWLLAAAVLARVD +RGAERLDRRIAYTRADLLGVSPVTEANVARGLSVAELCAAIVEVSDNAAANLLLASIGGP +AALTRWLRSQGDPVTNMVRNEPTLNSAIPGDARDTTSPAAMVGNLQRLVLGAALSAPSKA +RLIDSLTASRTGLKMLRAGLPADWRVGDKTGRGANASVNDVAVAWRPSGAPVLMAAYLTT +GDG--GAADGVIADLGRLVGARf +>[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=A0A165E8R5_9MICO +--EADSAFTQLEDDFDARVGVYAVDLDTGREL-AWRGDERFAYASTIKAMASAALLDEVG +--TDGLSKRVSISEDDIVSHSPVTETKVGGTMTLAELCEAAMTQSDNGAANLIFAELGGP +AALDERLNDLGDTGTTVSRTEPGLNEAKPGDPRDTTTPRASAGNLREYVFGGALEDDEAT +TLTDWMKATQTGDTLIRAELPEEWTVGDKSGTGYYGSRADLGIVWPGDGGPIIISVLSSK +DEKDAEADDRLISGAAAIAVE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID14446 TaxID=2706072 RepID=A0A6B2YNK3_9ACTN +-----PSFARLEREFDARLGVHAVDTGTGKAV-AYRPDEPFAFASTYKALAAGAVLRRNT +--PAGLERVVTYTQAELVAHSPVTGRHVESGMSLRALCDAAIRYSDNTAGNLLLGELGGP +KGFQAELTGLGDTTTRADRYEPALNEAAPSDPRDTSTPRALTSALYAYTLGGVLDGERRA +LLLDWLGRNTTGGALIRSGVPAHWKVGDKTGNASYGTRNDIAVVSPPGAAPILLAVLSSR +AARDAAYDDRLIARATEVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC333 TaxID=2070368 RepID=A0A2W2F3N9_9ACTN +--RAKKELRDLEKSLGVRVGAYAIDTATGRTI-GYRSGERFALASTFKAIAAAAVLHKAR +TEPGLMDKVVKWTADEVKPNSPITEKHVEDGLTVAQLCHAAITRSDNTAGNMLLKQLGGP +AGLTRYFRTLKDPVSRLDRWETELNDWSPKDKRDTTTPAAIARDLRLLTAGDALSAKDRE +RLNGWLLANTTGGARIRAGLPASWTVGDKTGTGGYGTANDIAVAWPKKGAPVIMAIYTNG +RTPGAAAQDKALADTATILA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0009A17B2E +-----ADFAALEKASGGRLGVTVLDTGSGRRIaGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRISLDTRVPIAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP +PALTAFLRAQGDAVTRNDRYEPEMNRFAKGDPRDTTSPAAMAASLARFAVGNGLSAASRL +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGEDTRNDIAVLWPRGGAPWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas TaxID=40323 RepID=UPI00066A15E7 +---AAADFAALEKACSGRLGVTLLDSADGRRL-GHRQDERFPLCSTFKSLLAATVLKQAE +RDPALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWILTAYLQA +GAISFEQRAAVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A5N0KTQ6_STEMA +----AADFAALEKASGGRLGVTVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLHLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVSGGP +PALTAFLRAQGDTVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGDGLSEKARL +QLADWLIDNQTGDACLRAGVGKRWRVGDKTGSNGEDTRNDVAVLWPRGGTPWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LFA0_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +AAVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas taiwanensis J19 TaxID=935569 RepID=A0A562E2Z8_9GAMM +----APDFAALEAASQGRLGVAVLEAGNGRYLaGHRADERFPMCSTFKALLAAAVLARAD +RGALDLDERLPVRAADLVPHAPVTRRHVGKDLGVRDLCRAIVTISDNTAANLLFARIGGP +AALTAFLRGLGDTVTRSDRLEPEMNGFVPGDPRDTTSPRAMATSLRRCVAGAVLAPASRL +QLADWLIDNTTGDDCLRAGIGPEWRVGDRTGSNGTDIRNDVAVLWPLAFQ---------- +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A2S1FM51_ACIBA +------------------VGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYL-- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754EC53 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI000459B5C7 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAICYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_031 TaxID=2175622 RepID=A0A2W1R3E2_9MICO +--ATARAFGALERRYDARLGVVAIDTGSGRTI-AHRAGERFAFASTVKVFIAAAVLDASS +--DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVGRLGGP +GAVERWLRGIGDRTTSVDRVEPDLNQAVPGDRRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVMTPPGRDPVVLVVMTSR +ADPGAEPSDALVAAATRAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis benzoatilytica TaxID=346045 RepID=UPI0003687BA8 +--AAQPDFSQLEKAFGARLGVFAIDTGNGREI-AYHADDRFAYASTHKVFTAAAILHRGE +----DLNRMITIRKSDLVPNSPITEKHLDTPMSLRSVLDAALRYSDNTAGNLMFREIGGP +AGLSSDLRRLGDTVTRVDRIEPALNETSPGDVRDTTTPRIWAADLRAAALGSGLPTDQQA +VLTGIMRASTTGTNAIRAGVPADWQVADKTGTADYATRNDIAVLWPPHRAPIVLAVLSDH +AQKDAKTDDKLIAQAASAVAK-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011231162 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPIYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] carbenicillin-hydrolyzing class A beta-lactamase CARB-47 n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI000400F856 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDESNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A104IBK7_9BURK +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptosporangium minutum TaxID=569862 RepID=A0A243QV82_9ACTN +--RARKELRTLEASFKGRIGAYAVDTATGKTV-AYRSGERFPLLSTFKAIAAAAVLHKAR +TDPGLLNKVVHWTTAELQGHSPVTEKHVKDGMTVARLCEAAVTQSDNTAANMLLKQIGGP +AGLTAYFRALKDPISRLDRWETELNNWSPKEKRDTTTPASMGRDLRAVTTGDALNAKDRA +RLNAWLIANKTGDARIRAGLPKSWTVGDRTGTNSYGAGNDIAVVWPGKSAPIIMSIYTNR +RAADAAADDKVIADTAAVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas cupida TaxID=44933 RepID=A0A1M7JSN2_9GAMM +-sDLQARLAELEQQHNGRLGIALMNLATGAVA-SHRGDERFLFNSTIKVIIAATILARVD +RGESALDRRLVVAESDLGGWTPITEQHLGEPMTVAELCQAAVAWSDNAAANVLFRELGGP +AAITDYLRTIGDDVTRSDRIEPALNEDHDGDERDTTTPLAMLQTLRALLFGDTLSPQSRH +QLVAWMVEGKTGDNRLRAGMPSSWLVAEKTGTSSGGNANDIGVAWPMDRGAVIAVAYTWL +PDAEPEQRDEVVAEVGKLA---- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura madurae TaxID=1993 RepID=UPI000D97E685 +------RYAALEREHGARLGVFAVATGTGATV-AYRAGERFAFCSTFKTLAAAAVLHRHP +--LAHLKDRVTYTRADIDSISPVTEDHVATGMTIRQLCDAAIRFSDGTAGNLLMRDIGGP +AGLTAYLRELGDGVSRMDDYEPELNRVRPGDPRDTTTPRAIAEDYRGLVLGTALPPDKRA +LIKDWLERSTTGAKRIRAGLPGGWKAAEKTGTGDYGRANDIAVVWPPRAAPLVVAVLSDR +PGRDARPDDALIAAATRRIV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075FA94A +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHDSGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759D6A1 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora shandongensis TaxID=418495 RepID=A0A1H3S3T0_9PSEU +------DLLALERKFDARLGVYALATGTGTAI-AHRADERFAFCSTFKALASAAVLHRNP +--LSYLDTLVTYTEADLMKSARITREHLTTGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +AELTAYTRSLGDAVTRMDRFEPMITEATPGDPRDTTSPRAIGTDFHRIVLGDALPTDKRA +FLRDLLERNVTGAKRIRAGLPSGWAAADKTGTGDYGTANDIAVVWPPNGEPLIISIMSSK +ATKDAEYDEALLAEATANVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007557B05 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Legionellales bacterium TaxID=2026754 RepID=A0A2E3MGJ4_9GAMM +--AADEKLAGLEHSFNGKIGVYAIDTNNGNII-AHRADERFPFQSTFKTIAAGALLYQAK +TDDDLLNERITYSQKDLVGWTPITKQHVKDGMTLEELAEAAVSYSDNGAVNLIMENLGGP +EAITRFANAIGNASFNVTNYEVNLNSN-PYDTSDTSTPKDMAISLQKLTLDDVLSPENKQ +KLTTWLTNNTTGNQRIRAGVPIGWTVADKTGSGDYGVANDIALAWSPFCKPIVISIYTNQ +TDSDAKNRDDIIAQTTEIVFA-- +>[subseq from] Beta-lactamase n=3 Tax=Mycolicibacterium smegmatis TaxID=1772 RepID=Q7WVE1_MYCSM +---VDDRIADLERRNNASIGIYAVDLDSNRTV-AHRADDSFAMCSTFKAYLAARILRGAE +RGELSLDDRVFVDPAALLSNSPITETHAGGEMTLAELCQAALQRSDNAAANLLLKQIGGP +AEITAFARSIGDQRTRLDRWETELNSAVPGDPRDTSTPAALAGGFRAVLTGDVLAPPQRQ +LLDEWMRANET--SSLRAGLPDGWTSADKTGSGDYGSTNDVGIAYGPQGQRILLALMVRT +RGPNADGFRPLIGELTALV---- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium smegmatis TaxID=1772 RepID=A0A0D6HY69_MYCSM +---VDDRIADLERRNNASIGIYAVDLDSNRTV-AHRADDSFAMCSTFKAYLAARILRGAE +RGELSLDDRVFVDPAALLSNSPITETHAGGEMTLAELCQAALQRSDNAAANLLLKQIGGP +AEITAFARSIGDQRTRLDRWETELNSAVPGDPRDTSTPAALAGGFRAVLTGDVLAPPQRQ +LLDEWMRANET--SSLRAGLPDGWTSADKTGSGDYGSTNDVGIAYGPQGQRILLALMVRT +RGPNADGFRPLIGELTALV---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI000757B9F2 +--AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVAAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA +QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] Beta-lactamase n=1 Tax=Salinicola sp. TaxID=1978524 RepID=A0A2D8P0U4_9GAMM +--DVQRKLEALEQRHGGRLGVALMNVATGAVA-SHRGDERFLFNSTGKGFIAAAVLARVE +RGEESMDRRIEVSQADLGGWTPITEKRIGSPMTIAELGQAAVAWSDNAAANLLIESVGGP +ESVTAFLRGIGDDTTRLDRMEPALNEDHEGDERDTTTPLAMMQTLRTLLLGEALSPSMRH +QLASWMIEGKTGDARLRAGMPAGWLIGEKTGTNSVGNANDIGIAWPADRGAVIAVAYTWM +PEASKAQRDQVIAEIGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia exalbida TaxID=290231 RepID=UPI0003118950 +----HDRLIELERKFDARLGVYARATGTGVTV-AHRADERFAFCSTFKGLAAAAVLQRNP +--LSHLDTVVTYTRDDLLKNATVTPRNVDTGMTIRQLCDAAIRYSDGTAGNLLLRDLGGP +AELTAYARSLGDPVTRMDRIEPAITEATPGDPRDTTSPRAFGEVYHRIVLGDALPGDKRD +FLRDLLERNATGAQRIRAGTPQGWRVADKTGTGDYGTLNDIAVVWPPDAAPLVVAIMSSK +ATRDAAYDQALLAEAAAYVMD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0005DA5757 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora spinosa TaxID=60894 RepID=A0A2N3XYC7_SACSN +-------FADLERRYDARLGLFAVNVHTGHVL-DHRADERFAMCSTFKTYAAAALLREHG +LDSGYFDKLIHYTEADLVAGSPITKPSAGTGMLVHELCAAAINRSDNTAANLLLAELGGP +AAIAPFARSIGDGSTRLDRWEPDLNTAIPGDERDTTTPGGIAAGHRALVVGDALGGPERD +RLTGWLFTNTTGGKRIRAGLPPTWRTGDKTGTGDYASANDVAVTWTDKGHPIVIAVLTTR +PRKDDEVNNGLHAETARIVAE-- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=UPI000769EABB +--KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACAAMLKDMD +SEKLDKNATAKVEERSMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID1328 TaxID=2690250 RepID=UPI00136A5561 +--ALRPELAALEKRYGVRLGVYAHNTRTGATV-AYRADEPFAMCSTFKAIAAAAVLRDHG +-GRAALGEVIHYPPADILSNSEQTKAHQETGMALGDVCAAAIQYSDNTAGNLMLRRIGGP +AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDARDTTTPRALGRTFELLTLGEALSDCDRE +QLVGWLRGNTTSGKRFGAGLPSDWVLADKTGTGSYATANDLGVAWTGKGTPLLLSVLSTK +PAPGAPVDEALIEETARLLA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A104TBG5_9BURK +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHDSGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TR1341 TaxID=2601266 RepID=UPI00138B08A2 +-----GELADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMDKVIHYPPHDLLPNSPRTEENQASGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP +AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALAAPDRE +RFVTWLKGNTTSGARFRAGLPEGWTIADKTGTGDYASANDIGVAWTTRRTPVVLAVLSTK +EGKDAPVDEALIAEAARIAAR-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. MH-G8 TaxID=1854588 RepID=A0A263DPD3_9PSEU +-------LTELERKFDARLGVYALDTGSGAAI-AHRADERFAFCSTFKGLAAAAVLHRNP +--LSHLDTAVTYGEGDLLKSAVVTRENVATGMTIGQLCDAAVRYSDGTAGNLLLRDLGGP +AELTAYTRGLGDTVTRMDRVEPHIVEATPGDPRDTSSPRALGTDYQRIVLDDTLPAEKRE +YLSDLLVRNTTGADRIRAAVPQGWTVADKTGTGDYGTLNDIAVVWPPDRAPLVVAVMSSK +ALPDAEYDEAVIAEAAAFVL--- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium pseudosasicola TaxID=582667 RepID=A0A1I4S0G7_9RHIZ +-qETELALTAIERRLGGRLGVSVG-TQAGVLL-SHRVDELFPMCSTFKVLAAAAVLARID +AGTDSLDRVIAFGPGDLLSYAPITRKTLDAGMTLSELCAAALEWSDNSAANLLLTALGGP +EALTRWLRSIGDPVTRLDRDEPTLNTALPGDPRDTTSPAAMRDTLGRVLLGSVLSAASRG +RLEAWMVASRTGLKRIRAGLPPDWPVGDKTGTGDNGTFNDVAILRPPGHAPVFACVYITG +AQVPAEAVEAAYAEIGRLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium canettii TaxID=78331 RepID=UPI0002A5959F +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREGLLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758B611 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000751BB27 +--TAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHDSGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075BFB28 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis complex TaxID=77643 RepID=UPI0008A8BAB0 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVGRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000760499C +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007535C1F +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007595FB2 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio jasicida TaxID=766224 RepID=UPI000CE55E0E +--KLNEDLASIEEHISGRLGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLKDMD +SEKLDKNATAKVEERNMVVWSPVMDRMVGQTTRIEHACEATMLMSDNTAANIVLRSIGGP +HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLEEy +>[subseq from] Beta-lactamase class A n=1 Tax=Caenispirillum bisanense TaxID=414052 RepID=A0A286GA81_9PROT +-----ARLADLERRHGGRLGVTILDVATGART-GWRQDERFLACSTFKALLAAHVLRRVD +AGQETLDRRIPVGKADLVPWSPVAETFVGTPMTVAQLCDAAVTMSDNAAANLLHAASGGP +AALTAFVRGLGDAVSRFDRTEPALNEDHAGDERDTVAPASMAATLHALLFEEALSRRSRD +LLRGWLVTNRTGDARLRAGFPATWLVGDKTGTNGSGTAADVAAVWPNTRPPLVVTAYYEV +RGASADARNAVLAEVGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075972A0 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces violens TaxID=66377 RepID=UPI0004BF7DE0 +---LSGQLKRLEREHAARLGVFARDLATGRTV-RYRADERFPMCSVFKGLAAAAVLRDLD +HDGEFLAKRIHYTKKYVTDYAPISSENVAHGMTVTELCAAAVSHSDNGAANLLLRELGGP +TAITRFCRSLGDDETRLDRWEPQLNSAEPWRTTDTTTPRAIGTTYGRLVVGRALAAEDRK +RLKDWLIANTTNTKRFRAGLPDGWITADKTGGGSYGVANDVGVAWPPGRSPVLLSVLTTT +HAPEGPSDDALVAKAAELVA--- +>[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0009EC2150 +--AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDCCIAEVGRLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Jiangella ureilytica TaxID=2530374 RepID=A0A4R4RNX3_9ACTN +--AVAAALAQLETDYAARLGVYAVDTGTRETV-EHRADERFAFASTHKALSAAAVLQATD +--AAALDDVIQYDAADVVGHSPVTEPAAGTGLTLLEVIRAAITVSDNTAANLLFEQLGGP +DGLEAAVRGFGDDTTSFDRIEPGLSDWAPGETRDTTTPRAMAANLERLALGDLLAADDRA +VLVDAMRDNTTGDELIRAGVPDGWPVADKTGSAGHGGRNDIAVIEPPDSAPIVLAVYSNR +LDPEAESDPALIAAAATIVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0013DA16C7 +---LSGRFRALEKRYGARLGVYAHDPRSGRTV-RYRADTLFPQCSLFKTLAAAAVLRDLD +RDGEVLARRIRYTEADLVEGSDHTRENLATGMTVAALCDVAIRFSDNTAANLLLRELGGP +TAITRFARSTGDRVTRLDRWETELNSAEPWRTTDTTSPSAIGRTYARLVLGDALNRCDRS +RLTDWLLRNKTSGTRLRAGLPGTWTVADKTGGGPYGTNNNVGIAWTDDGSPLVLSLLSRM +PERDAVKNDALIAGAAAVLAD-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001302D56F +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLVLEHy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02261 TaxID=1703940 RepID=A0A1Q5IZS5_9ACTN +--RLVGRLRELERRHSARLGVFAHDVRTGRSV-AFRAEERFAMCSVFKTLAVAAVLRDLD +HDGTFLERRIRYTEAYVERYSPRTEENLAHGMTVAELCDATLRHSDNTAANLLLRELGGP +TSVTRFARSVGDLTTRLDRWEPELNSAEPWRRTDTTTPRAIGLTYGRLLLGDALPREDRN +RLTGWMLANTTSGERFRKGLPADWLLADKTGGGRYGGNNDAGVTWPPDGGPIVLVVMTTR +FEEDAPPVDALVADAAALVAS-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ag109_O5-1 TaxID=1938851 RepID=A0A3N4SL02_9ACTN +---AASRFQALEREHRARLGVFAWDTGSGARI-RYRCGELFPMCSVFKTLAVAAVLRDLG +--EEVLAEVVHYDERDVERGAPVTGKNLASGMTVAELCAAAIEYSDNTAANLLLEQLGGP +VAVTRLCRSLGDEVTRLDRWEPELNSAEPGRVTDTTTPLAVGVSYARLVVGDALDGADRR +RLTGWLRANTTGGERIRAGLPGDWTVGDKTGTGGYGTANDVAIAWPPGRAPVVLAVFSTH +IEATAQADSPLARKAAAVVTDAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075A2F93 +--AAQAELAALEKASSGRLGVAALDTSNGTRV-AYHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA +QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] CBP family penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=UPI0007DFB8A9 +---YNSAFSKIESDYGVKLGVYAFNTETNKEV-TYNADKRFAYCSTFKSLISGAILQKYS +--SDQLKQVIKYSPKDVLSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP +NGFKSALNQLGDTVTEPARIEPELNVATPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKK +ILINWMSGNATGDKLIRAGAPKDWIVSDKSGTGSYGTRNDIAIVIPPNKKPIFVAILSSK +SAKDAKYDDETISEASKIVFDYf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758068C +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. SWH-M5 TaxID=1490483 RepID=A0A1Q4TPE1_9MYCO +-------IADLERRHNALIGIFAANLDSNRTV-AHRADEPFAMCSTFKTYLAARVLQKAE +RGELSLDDRVFVDPSVLLVNSPITETHAGGEMTLAELCQAALQRSDNAAANLLLTKIGGP +AEITAFARSIGDQRTRLDRWEIELNSAIPGDPRDTSTPAALGGGYRALLAGDALSPPQRQ +RLDEWMRANQT--SSMRAGLPDGWTSADKTGSGDYGSTNDVGIAYGPQGQRILLAVMTRS +RDDDAPGLRPLIGEVTALV---- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Nocardia TaxID=2637762 RepID=UPI00135AC3BF +----HDRLIELERKFDARLGVYARATGTGATI-AHRADERFAFCSTFKGLAAAAVLQRNP +--LSHLDTVVTYTRDDLLKNAAVTPRYVDTGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP +AELTAYARSLGDMVTRMDRIEPAITEATPDDPRDTTSPRAFGEVYDRIVLGDALPVDKRD +FLRDLLERNATGAQRIRAGVPQGWKVADKTGTGDYGTLNDIAIVWPPDSAPLVVAIMSGK +ATRDAAYDQALLAEAAAYVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora cremea TaxID=709881 RepID=A0A1N5WJ81_9ACTN +---HHDHLASLERKFDARLGVYALATGTGATI-AHRADERFPFCSTFKGLAAAAVLHRHP +--LSDLSSVVRYTRDDLMESSVITRQHVARGMTLRQLSDAAVRYSDGTAGNLLLRDLGGP +RELTAYVRGLGDTVTRMDRIEPAVASAIPGDPRDTTSPRALSTNYQHIVLGEALPPDKRA +FLRDLLERNATGAQRIRAGVPRGWTVADKTGTGGYGTVNDIGVVWPPAAAPLVIGIMSSK +AEKDTEHDQALIAEAAAYVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FEAD73 +--AAQSQLDALEQGSNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDTSLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. A244 TaxID=2137016 RepID=A0A2T4NJW8_9ACTN +------RLADLERAYGARVGVYALATGTGATV-VHRAGERFAFCSTFKALAAAAVLHHRT +--LSGLDRRVTYTKADLRSTSPVTGRHVATGMTLRELCDAAVRFSDGTAGNLLMRDIGGP +PKLTAYLRSLGDEVSRMDHYEPELHDVPPGDPADTTTPQAIATDFRRLLLGTALPARERR +LLMDWLSRNGTGARRIRAGLPGGWKVADKTGTGDYGRANDIAVVRPPRTEPLVLAVMTDR +SGRDAEPSDALIAEATRRT---- +>[subseq from] class A beta-lactamase n=1 Tax=Thermomonospora catenispora TaxID=2493090 RepID=UPI00111DCE32 +--EVQRRLRALEAGYNGRIGAYAIDTATGRTV-GYRAQETFALNSTFKALACAAVLHKAR +TDPGLLDRVIRYTADDLVEYSPETEKNLRSGMTVSALCEAAITLSDNTAGNLILRQIGGP +AGMTAFLRSLGDHRSRLDRWETDLNDWRPGEYRDTTTPALMAQNLRKVTTTDALAEPDRA +RLIAWMRANTTGDARIRAGLPADWTIGDKTGTGRYAPAADIAIVWPKGAAPLIMAIYTNR +TTPDTEVDDRVIARTATVLAQ-- +>[subseq from] Uncharacterized protein n=2 Tax=Xenorhabdus TaxID=626 RepID=A0A2D0KBP5_9GAMM +-kQIINQLTALEQSANGHLGVVLINSADNSTI-GYRANERFPLCSTSKFMAVSALLKKSE +TDENLLKQRVNYKQSDLVEYSPITGKYIETGKTLAELSAATLQYSDNTAMNLIINQLGSP +ERVTTFARTLGDMMFRLDRKEPELNLVQPGDERDTSTPQAMAESLYKLALGDFLATNQRT +QLVEWLKGNTTGNASIRAGVPKDWIVGDKTGRCDYGSTNDIAVIWPSNRAPLVLVTYFTQ +PGKNAKARPDVLAEAARIIIQ-- +>[subseq from] BlaL family class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5053 TaxID=1463854 RepID=UPI0004C538D3 +--AHEKEFRALEKKFDATLGVYAIDTADGQEI-THRADERFAYGSTFKALQAGAILRKFS +AEADGMDKVVHYGQDAILPNSPVTEKHVADGMSLRELCDAVVRYSDNTAANLLFDQLGGP +KGLNAVLKQLGDHTTSMDRYEQELGSAVPGDPRDTSTPRAFAEDLRAFAVEDALAPNDRE +QLNDWMSGNATGDALIRAGVPKDWKVADKSGQVKYGTRNDIAVVRPPGRAPIVVSVMSHG +DTEDAEPHDELVAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Crossiella equi TaxID=130796 RepID=UPI000A3A1F09 +-----AAFDALEREFDARLGVYARHTGTGAEL-AHRADERFAFCSTFKALATAAVLHRNP +--LSHLDTLIRYGKGDLMRNGPITARNVERGMTIRELADAAVRFSDGAAGNLLLRDLGGP +AELTAYARSLGDDLTRMDRVEPFITEATPGDPRDTTTPRAFGRCFEKVVLGDALPPDKRA +VLRDLLERNTTGDKRIRAGLPPGWRAADKTGTGDYGTANDFALVWPPDGAPILIALMSSK +ATKDAAYDQALLAEAATAVTRAf +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LFA8_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATTLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGVDMTVRDLCRATIITSGNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides saopaulense TaxID=1578165 RepID=A0A1S4VW56_9MYCO +-----NEFAALEKNFGGRIGVYALDTGSGRTV-GHRADERFLMCSTVKTFIVSAILHRRR +SVPSLLDKRIQYTQADLLEWAPITSQHVAEGMSVSQLCDATIRYSDNTGANLLIAELGGP +KETEKFVRGLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD +LLTDWLKRNTTGDQSIRAGVPSGWTVGDKTGSGFKGETNDIAVIWPPGRAPIVVAVLTVP +EDPKSTQGKPTIAAATRIALQAf +>[subseq from] Carbenicillin-hydrolyzing class A beta-lactamase CARB-41 n=2 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A646LGQ0_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRVEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=2 Tax=Arthrobacter sp. PAMC 25486 TaxID=1494608 RepID=A0A0A1CSU8_9MICC +----DTEFVALEKKYDARLGVFAVDSRTNAAV-SYRADERYAFCSTYKALAAAAVLNQRT +--VHELDEVIHYAREDLVAYSPVTEKHLEQGMTVRALCEAAVRHSDNTAGNLLFQELGGP +QGLNGKLRELGDDVTQMDRVEGALNSAVPGELLDTSTPRALANDLRHYALGSGLSAEKSA +IFNDWLEGNATGANLVRAGVPQEWKIGDKSGAGAYGTRNDIGIIHPPAGNPICIAVLSTR +TTPDATYDDKLIADATRIAVQH- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI0002E25444 +--KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD +NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLRTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] class A beta-lactamase n=1 Tax=Acuticoccus sediminis TaxID=2184697 RepID=UPI000DAC2C51 +-dRLADTIRTLETDIDARIGVLVRDSASGWEW-GHRQDERFLMASTFKSLLCGAVLAQVD +SGALSLDEPIEIGEEDMVEYAPTTEKHIGGSMTVGDLCFATLDLSDNPAANLLIERLGGP +QAVTAFARSTGDEVTRLDRFEPELNVFDPDDPRDTTSPTAMLSTWEAMLRGDALSATSRD +QLEEWMSHGGVTGKLIRAETPDGWTVADKSGSGEGYTRNLVAMVTPEDRPPYFVAIFVSD +SPTDFTTRNGALSRIGAAVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. NGS-ED-1003 TaxID=1526743 RepID=UPI0005341117 +------VAQQEEQALKARIGIAVIDTGAESVA-SYRGNERFPLNSTHKALLCGALLSAQE +QCKLRLTERTQFDRAALVTYSPVTEKFVAPAMSWGQLCEAAIGYSDNTAANLLAKKLGGP +EAVTRFFADLGDKVTRLDRFEPELNSAVPGDMRDTTTPLAVSETLQKLTLGTALTPASRA +QLLQWMRDDKVANALLRSVLPAGWSIADKTGAGEYGSRSIISVVSPENGKPLIIAIYITQ +TEATLAQSNAAIARIGKTIF--- +>[subseq from] class A beta-lactamase n=1 Tax=Oleiagrimonas sp. C23AA TaxID=2719047 RepID=UPI001420A718 +---LHTRLAALEARHGGRLGVAMLDTGTGAQL-RYRADHRFMMCSTHKVLTVAAILARVD +RGTERLDRRVVYGRDVLLEYAPTTRAHVGPPMTIEALCQAAITLSDNTADNLLLAQLGGP +EAVTGFVRSLGDHITWLARTEPALNYAMPDDHRDTTTPDAMLADLKALLLGTALSPASRL +RLLGWMQACQTGTQMLRAGLAAHWRCGDKTGSGPANELNDVAIVHPPGAAPLLITSFYAE +SVASLEERHGVIADIGRLAV--- +>[subseq from] Beta-lactamase n=1 Tax=Agreia sp. VKM Ac-2052 TaxID=123316 RepID=A0A1T4Y7Z1_9MICO +------AFAQLEQEFDARLGIYALDPDTRAEV-AYRADERFAYASTFKALAAGILLKTVS +--DDELDGLITYDAGDLLPNSPVTEANVDNGMTLRAVAEAAVRFSDNTAGNIMLEHLGGP +EGFTQALRELGDTTSSSDRIETELNSAIPGDTRDTTTPRAFALDLATLLTTDALGAAQQS +QLIDWMTGNATGAELITAGLDAGWSVADKSGAGAYGTRNDIALLWPPSGSPIVLVVMSNR +PTEDADYDNALIARAAEAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonadales bacterium TaxID=2006849 RepID=A0A2E5G0C5_9GAMM +---FLARMDALEARHGGRLGVSVRDTTGRLAV-SHRGDDRFLLCSTVKLPLAALILSRVD +AGHESLERPIDYAEADLVTYSPETEQHVATGMTLGAICRAGLTQSDNTAANLMFDAVGGP +PALTDFIRSLGDTTTRSNRLETALNEPT-PDARDTTTPRAMRALMTKILLGDVLSPAARD +RLLSWMKANQTGDQRLRAGLPSAWPIGDKTGSGGNNTAADIAIAHPAPAHAIVISAYYAD +SSASRDARDQVLADVGRAVADLy +>[subseq from] UPI0012FE7EB9 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0012FE7EB9 +-sKLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces lavendulae TaxID=1914 RepID=A0A5C8GYC9_STRLA +------ELADLERRYGARLGVYARNTRTGRVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMDKVIHYPPHDLLPNSPRTQENQATGMAMADVCAAAIQYSDNAAGNLLLRRLDGP +AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALAASIERLALGRALAAADRE +RFVGWLKGNTTSGARFRAGLPKGWTIADKTGTGDYASANDMGVAWTTRRTPVVLAVLSTK +EGKDAPVDEALIAEAARIAAR-- +>[subseq from] Beta-lactamase n=1 Tax=Kitasatospora sp. CB02891 TaxID=2020329 RepID=A0A2M9L9T6_9ACTN +-----DPFHQLEQRFGARLGVYVLDTGSGREI-THHADERFAFASTSKALAAGALLRRAS +--DADLEKVVTYRQADVLTWAPVTSKHVDTGMTLRDLLAASLDHSDNTAANLVTAEVGGP +AAVQQALRDLGDITTHVDRTEPTLNETAPGDTRDTSTPRALAADLRQYVLGDVLPADRRR +LLTDLMLANTTGGPYIRAGVPAGWKVADRTGNADHGTRNDIAVAWPGGGSPVVIVVLSDR +ARPDAASDDELIARATEAALN-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00047149EA +---AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDPALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA +GTISFEQRAAVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. DconLS TaxID=1839766 RepID=A0A1C5DRH0_9ACTN +-----GELADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP +AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALTAPDRE +RFVTWLKGNTTSGARFRAGLPGGWTIADKTGTGDYASANDIGVAWTTRRTPVVLAVLSTK +EGKDAPVDEALIAEAARIAAR-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus M0605 TaxID=1449358 RepID=X7R747_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILDHy +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00045A6AA7 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRDSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Root1310 TaxID=1736452 RepID=UPI00099ECFB7 +---VTDRLRDLEAGHGARLGVFAHNVRTGRSV-RYRADERFPVCSLFKTLAVAAVLRDLP +--EGTPDRRVFWTAADVVENSPVTQEHVADGMTIAELSAAAIQRSDNTAGNLLLRELGGP +AALTRFARSVGDRVTRLDRWEPELNSAEPDRITDTTSPYAIGRTYARLVLGDALAPADRR +RLTDWMLGTVTSANRFRAGLPPTWTLADKTGGGWYGANNDAGIAWTPDGTPVVLVVQLTK +PARDAAYDHELIVETAGLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Comamonas kerstersii TaxID=225992 RepID=UPI000985D27E +--SLQAHCQALEAKAQGRLGVSIVDTATGQQW-GWREDERFMMLSSFKLLASALVLHRVD +QGQESLQRRMAYPRSALIPWSPITEKHADGPLTLGELCAATITTSDNTAGNLILESYGGP +AALTAYARQLGDAVTRLDRNEPTLNRPSSDGLLDTTSPRAMAQTMHKLLVGGALSTASRQ +QLRQWLLANTTGGKRLKAGVPASWQVGDKTGTNAT-DANDIGFLIPPQGAPWIVTAYLAG +SSAEGAVKDACLADVAAWVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005E82328 +--DLADRFAELERRYDARPGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001121DB32 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSALPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Comamonas sp. B-9 TaxID=1055192 RepID=UPI0003FA474E +--QFAQAMQALERAVGGRLGVSALNTVTGAAL-GWRQNERFAMCSTFKMLLAAQVLSRVD +AGQDRLDATLTFDRSVLVEHSPVTEKFAGKAMTVEALCDAIMTISDNGAANLLLERVGGP +ASFTAYMRSLGDPTTRLDRIEPAMSESKPGDVGDTTSPLAMLSSMRALTLGKALSAANRE +RLVGWMQANTTGDHCLRAGAP-GWKVADKTGSGP-GTRNDIGLLWAPGATPILVTSYLTE +CKAEPKARDAALARVAAELVKLw +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011231127 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces lavendulae subsp. lavendulae TaxID=58340 RepID=A0A2K8P756_STRLA +--DVLRQLRALEQEHSARLGVYARDTATGRTV-LHRAEERFPMCSVFKTLAVAAVLRDLD +RDGEFLATRLFYTEQEVKDFGPVTGENLAAGMTVERLCAAAICQSDNAAANLLLRELGGP +EAVTRFCRSVGDRTTRLDRWEPELNSAEPGRLTDTTTPRAIGRTYGELVLGDALAPRDRE +RLTGWLLANTTSTERFRKGLPADWTLGDKTGGGAYGTNNDAGVTWPPHRPPVVMVVLTTH +DRPDAVADNPLVAKTAALLA--- +>[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia TaxID=1822464 RepID=I5CW11_9BURK +---ARERFEKLEASSGGRLGVAALNMADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM +AERSLLDERVRYGDADLVANSPVTKRRAGEGMTIGELCAAALQHSDNTAANLLLTAVGGP +EVLNQFALSIGDEWFDLLRGEPEVNGSVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE +QLKAWMLGNATGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG +VTKQTLPRDEVVAEAARIVFD-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium boenickei TaxID=146017 RepID=A0A2A7P2D7_9MYCO +---VDDQIADLERRHNALIGLYAANLDSGRTL-AHRSDEMFAMCSTFKGYAAARVLQMVG +RRQISLDNRVFVDREAIVPNSPITETHAGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALASGYREVLAGDALSPPQRR +LLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPDGQRVLLAVMTRS +QADDADNLRPLIGELTAAV---- +>[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. TaxID=267 RepID=A0A2G1Z1T6_9RHOB +-eTLAATVAQIESQFDSRVGIAIVDTGSNFTW-SHRDDERFLMNSTVKVPICGAVLARAD +VGSLSLSQDLPIRQSDLVDYAPVAERHVGGDMTIAELCLAAIDQSDNTAANLLIDHLGGP +QAVTGFFRDLGDPVSRLDRYEPALNSFAPGDPRDTTTPAAFAESLRRMLLGDALSPASRN +QLAEWMRHGGVTGKLLRRDAPAGWRILDKSGSGSH-NRNIVAVINPDDAAPWIVTIFLSD +MDADFATRDAALQRIGSDVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura rayongensis TaxID=1429076 RepID=UPI001354B089 +--SVTARIDALERSYAGRIGAFALDTGTGRVV-AHRADERFAFASTFKAALAATVLHKAR +SDPGLLHRRLHWTADDLLPNSPVSEQHVADGLTAAELCRAAITQSDNTAANVLLKQVGGP +AGVTRYLRSLGDPVSRLDHTEPALNQWKPGQRQDTVTPAAIGRDLASVTVGRALPAPDRA +QLNAWLRATVTGDARIRAGVPKNWLVGDKTGTGSYGTANDIAVVTPPGHAPVIIAVYTNR +NDPKGSPDESVIARTATLLVE-- +>[subseq from] Beta-lactamase n=1 Tax=Embleya hyalina TaxID=516124 RepID=A0A401YM29_9ACTN +----TGRLRALERAHAARLGVFACDVHSGRTV-VHRADELFPMCSTFKTIAVAAVLRDLD +RDGEFLGRRIRYTEKDVTEYAPITGRNLADGMIVADLCAAAIAYSDNGAANLLLRRLGGP +GAVTGFCRSVGDGVTRLDRWEPALNSAEPGRVTDTSSPRALGRTYARLALGGALDARDRE +RLNGWLLANTTGGKRLRAGLPPDWVVADKTGTGDYGTTNDVGIVRPPGRGPIVMAVLATK +DDAAAPADEPLLAGTATVLAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. TLI_105 TaxID=1881019 RepID=A0A1H5FN79_9ACTN +-----ARLRRLEREHTARLGVFARDLRTGRTV-AHRADERFPMASVFKTLAVAAVLRDLD +RDGEFLARRVHYTQAYVARISPVAGENVSGGMTVAELCDATIRFSDNTAGNLLLKELGGP +TGITRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTTPHAIGLDYARLVLGDVLEPHDRA +RLTDWLLRNTTSTEKFRRGLPADWLLADKTGSPRYGGANDVGIAWRPDGTPIVLAVLTTQ +PEEDAPTDNPLVAGTASLLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Sporolactobacillus terrae TaxID=269673 RepID=UPI0009DF7E4A +---TDQAFVQLEKKFDARIGVYAFDSGTQRTV-AYRPDDRFAYASTYKALAAGAVLQQSS +--IHQLNEVILFSKDDLVTYSPIAENRVNSGMTLGEICEAAIRYSANTAGNLLLKKLGGP +NGFEKTLNKIGDNVTKANRFETDLNETIPGDLRDTSTASALATDLKAFSVGKAPPTHKRK +MLADWMRGNTTGDQLIRAGVPKGWAVADKSGAGGYGTRNDLAIVWPPKRLPIILAILSSR +DTKDAPYHNELIAEAAKLTI--- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_040 TaxID=2175625 RepID=A0A2W1V598_9MICO +--ATARAFAALERRDDVRLGVVAVDTGDGRTI-VHRAGERFAFASTIKVFIAAAVLDASS +--DADLATVVHYDRGDLLEYAPVTREHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP +HAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR +VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR +ADPGAEPSDALVAAATRTAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DE56F5 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNPTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis panacis TaxID=2340917 RepID=A0A419I939_9PSEU +------DFGALKHSFGARLGVYAVDTGSGREV-AYRADERFAYASTHKVFSAAAILKRDD +----DLNQVIKYQAGDLVTYSPITEKHVGTGMPLRDVLDAALRYSDNTAANLMFRQIGGP +AALGASLRGLGDITTHVDRTEPTLNEATPGDLRDTTTPRAWAADLRGCALGRGLTPDDQK +VLLDMMRANTTGATVIRAGVPAGWQVADKTGSAEYGGRNDIAVLWPPHRAPIVLVLLSSK +PAKDAKSEDKLLARATTEVVR-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00031E7033 +--ETAAAFRKLERKYDARLGVHAVDTGTGREI-SFHAGERFAYASTHKAFTAAAILDKRS +--LSGLDKVITYRKEDLLPHSPVTREHVEEGMTLRALCAAALRQSDNAADNLLLRELGGP +KALDAFLEKLGDDVTNVNRYEPELNEAAPGDDRDTTTPRAWTADLRAVALGDGLNRKEQA +QLDDWMRNSPTGKTLIRAGVPEKWTVSDKSGGGRHATRSDIAVVRPPGGAPLVVTVMSRR +TERDAEYDDRLVADAASVVADE- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000C7D9FE2 +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEQDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Agreia bicolorata TaxID=110935 RepID=UPI0005E8909F +------AFAQLEQEFDARLGIYALDPDTRAEV-AYRADERFAYASTFKALAAGILLKTVS +--DDELDGLITYDAGDLLPNSPVTEANVDNGMTLRAVAEAAVRFSDNTAGNIMLERLGGP +EGFTQALRELGDTTSSSDRIETELNSAIPGDTRDTTTPRAFALDLATLLTTDALGAAQQS +QLIDWMTGNATGAELITAGLDAGWSVADKSGAGAYGTRNDIALLWPPSGSPIVLVVMSNR +PTEDADYDNALIARAAEAAL--- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces zhaozhouensis TaxID=1300267 RepID=A0A286E5G1_9ACTN +--EAAAEFEALEGEFDARLGVYALDTGTGAEV-AHRDGERFAYASAFKALLVGAVLDEYG +--TAGVEEVVDYTEDELVDYSPVTENFVDSGMSLSQLSAATLWYSDNTAANLLLEAVGGP +AGLQEALREMGDDTTEVSRYEPELNEATPGDTRDTSTPRAMAEDLRALLLADALGERERH +LLRQWMETNTTGGTLVRAGLPAEWTVADKSGSAGYGGRNNIAVVWPDDGDPIVLAVLSSR +DEEDAERDDALIARAATAAVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium TaxID=379 RepID=UPI000645558D +----EAQLAALESKHPGRICVSVLDMASGKRI-EHRPGERILICSTFKTLAAALVLARVD +KGEEKFDRRVHYTERDLVDSSPATKANVGKGMTIAELCAAMMTLSDNTAGNLLLASFGGP +GALTTFCRSLGDEITHLDRLEPELNYDTPDDQRDTTTAAAMLENLRRLLFTDVLSPASRL +QLAAWLMTNRTGDTRLRAGLPKNWLAGDKTGTNGDGNANDIAVLWPSNRAPIIVTAYCEI +PAIAADERNAIIAEIGRIAA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111CBB16 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHf +>[subseq from] Beta-lactamase class A n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A3N1Q1E4_STEMA +---TAADFAALEKASGGRLGVTLLDTRTGKRA-GHRQDERFPMCSTIKWMIAAAALHRAE +RQPGFLDERLPMRSEDLIEHAPTTRRHVGKDLSVRDLCRTTMVTSDNPAANLLLRRLGGP +PALTAFLRSHDDAVTRSDRYEPELNRFTPGDPRDTTSPAASAASLQRFVLGDALQPASRQ +QLADWLIDNETGDATLRAGLGARWRVGDKTGSNGKDTRNDIGVLWPLGGSAWVLTAYLQG +ASVDSGQRDAVLARVAAL----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TLI_053 TaxID=1855352 RepID=A0A1H1ZNP1_9ACTN +--EVTDRLRALEQSHAARLGVFAHNLATGRTV-AHRADELFPMCSTFKTIAVAAVLRDLD +RDGTFLAERRHWTTTDVTEYAPITGENLEGGLTIEELCAAAIRYSDNAAANLLLRELGGP +EAVTRFCRSVGDRVTRLDRWEPALNSAEPDRITDTSSPRALTRTYTRLTLGSALTPAHRR +RLTTWLLTNTTGTDRLRAGLPSTWTTAEKTGTGNYGTTNDAGVTRPPTGGPIVLTVLSTQ +HIAAAPADEPLVAEAARLVA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00066A06A2 +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011225645 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAEISQLILEHy +>[subseq from] Beta-lactamase class A n=1 Tax=Georgenia satyanarayanai TaxID=860221 RepID=A0A2Y8ZXA4_9MICO +-----------AAESGVTLSVAVTDLADGATL-IAGEDERVKAASIIKLPLLATLMADVD +AGELDLDQTVTIPAGDIVGGSGTLKDQFPLDITVAELMELMVQVSDNTATNVLIDLAGGF +DAVNDYVEALGFEDLYLGRKMI--HPASPPLQENYISAEEVTELVTLLWEGEILSAESSE +HIIDLMRGQLV-DTKFGAVIP-RAHLANKTGELAD-VSHDSGIVLLPGRE-LAFTTTTSF +TDLPRAEADVFVQETARVVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Georgenia satyanarayanai TaxID=860221 RepID=A0A2Y8ZXA4_9MICO +-------------AQDVRVSVGFSDLADGDRV-LLGSQEPYNPASVIKLSLLAAVMRQTE +RDLLHLDAPVTISPYMVVGGSGSFQDEMPFTTTVRELVRRMVVESDNTATNVLLYHI-GL +PTTQELIDDLGLDVMRFNRQMFPG--ELIDEPANVLDVGDTLALLEAMYGDELLGEESRE +QILTWMSDQEV-DTKFGAVLN-DAPVAHKTGETGN-VTHDVGYFLVPGHE-AAVVVLTEV +TNETQEIGNPIVQEIGLAVYDY- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio rotiferianus TaxID=190895 RepID=UPI001110B76F +--KLNEDLTAIEQHIGGRIGVSVWDTQNDEHW-DYRGDERFPMMSTFKTLACATMLSDMD +SEKLDKNATAKVEERNIVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +NGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITK +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SA81_KLEPN +---------------VGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVV----- +----------------------- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0003EA70BC +---AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDAALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA +GTISFEQRAAVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Lentzea jiangxiensis TaxID=641025 RepID=UPI000B7FA1FD +--TVTGRLRELERQHNARLGVFATDTGTGRTV-LHRADELFPMCSTFKTIAAAAILRRDR +-DGSLLRKVITYTQSDVDKHAPVTGRNLANGMTVAALCEATITHSDNCAANLLLRELGGP +TAITRFSRSIGDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGQSYARLTLGHALNPNDSD +QLTNWLLANTTGGNRIRAGLPSAWRWGDKTGTGKYGTTNDAGIAFPPGRAPIVIAVLSTR +QDPTGGADEPLLAETAELVA--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0R5RQ02_9BACT +--TFQQTSANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP +--EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV +EQYQRILRQLGDNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT +ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ +FTEEAKFNNKLVEDAAKQVFH-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0R5RQ00_9BACT +--TFQQTSANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP +--EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV +EQYQRILRQLGDNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT +ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ +FTEEAKFNNKLVEDAAKQVFH-- +>[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4S1MIU2_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRASLDTRVPIAEQDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus TUMSAT_DE1_S1 TaxID=1441607 RepID=A0A0I9RJ70_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATARINERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TLI_105 TaxID=1881019 RepID=UPI000B868114 +-----ARLRRLEREHTARLGVFARDLRTGRTV-AHRADERFPMASVFKTLAVAAVLRDLD +RDGEFLARRVHYTQAYVARISPVAGENVSGGMTVAELCDATIRFSDNTAGNLLLKELGGP +TGITRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTTPHAIGLDYARLVLGDVLEPHDRA +RLTDWLLRNTTSTEKFRRGLPADWLLADKTGSPRYGGANDVGIAWRPDGTPIVLAVLTTQ +PEEDAPTDNPLVAGTASLLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Saccharopolyspora flava TaxID=95161 RepID=UPI000B8762A3 +-------LVELERRYDARLGLFARNAATGRTL-AHRADERAALCSTFKVYASAALLRAHG +LAGGYFDRVIRYDAGQLVEYSPITETRVGTGMTVGELCAAALQHSDNTAGNLLLRELGGP +RAITDFARSIGDPVTRLDRWETELNTAVPGDERDTSSPKALADGLQALLLGDVLGAPERD +LLTRWMLGNTTGDARIRAGVPGDWRTADKTGGGSYGVANDFAVTWTGTGTPIVISLLTGR +PRAEDAANNALLAEATRLVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces cacaoi subsp. cacaoi TaxID=66857 RepID=A0A4Y3R644_STRCI +----AAELKALEDEFDVRLGVYAVDTGSGREV-AYRDGERFPYNSTFKALECGAVLDKHT +--DREMDRVVKYSEDDLVDNSPVTEKHVEDGMTLTALCDAAVRYSDNTAANLLFETVGGP +KGLDKTLEGLGDHVTRMERVEPFLSRWEPGSKRDTSTPRAFAKDLRAYVLGDVLAEGDRK +QLTTWLRNNTTGDGLIRAGVPEGWVVGDKTGTGSYGARNDMAVVWRPDAAPLVLNVMVHG +HTKDAELDSELIARATEVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium casei TaxID=33889 RepID=UPI00119F6A92 +--EADSAFTQLEDDFDARVGVYAVDLDTGREL-AWRGDERFAYASTIKAMASAALLDEVG +--TDGLSKRVAISEDDIVSHSPVTETKVGGTMTLAELCEAAMTQSDNGAANLIFAELGGP +AALDERLNDLGDTGTTVSRTEPGLNEAKPGDPRDTTTPRASAGNLREYVFGGALEDDEAT +TLTDWMKATQTGDTLIRAELPEEWTVGDKSGTGYYGSRADLGIVWPGDGGPIIISVLSAK +DEKDAEADDRLISGAAAIAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis decaplanina DSM 44594 TaxID=1284240 RepID=M2YBH8_9PSEU +-----ADFERLERTFGARLGVYAVDTATGREV-AFRAEERFAYASTHKVFSAGGVLQRTP +--VADLDRTVTYGRKDVVADSPVTEKHVATGMPLRAVMDATLRYSDNTGGNLLFRELGGP +EGLNAVFRGIGDTTSHADRIEPALNDTAPGDNRDTSTPRALAVSLRAFALGDALPEDKRK +ILVDMMRANTTGDQNIRAGLP-GWPVADKTGTAAYGTRNDIGVVWPPNRAPIVISVLTDR +PDKDAKIDNKLLAEATAAAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces qaidamensis TaxID=1783515 RepID=A0A143C3U9_9ACTN +------RLTDLERAYGARVGVYALATGTGATV-AHRAGERFAFCSTFKALAAAAVLHHRT +--LSGLDRRVTYTEADLRSTTPVTGRHVATGMTLRELCDAAVRFSDGTAGNLLMRDIGGP +PKLTAYLRRLGDEVSRMDHYEPELHDVPPGDPADTTTPQAIATDFRRLLLGTALPARERR +LLMDWLSRNATGARRIRAGLPADWKVADKTGTGDYGRANDIAVVHPPRTEPLVLAVMTDR +PGRDAEPSDALIAEATRRAV--- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI000681511C +--KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD +NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPIYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia hospita TaxID=169430 RepID=UPI000271BEE2 +----RGRFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM +AERGLLDERVRYGDADLVANSPVTKRRVGEGMTIGELSAAALQHSDNTAANLLLTAVGGP +EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE +QLKAWMLGNATGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG +VTKQTPPRDEVVAEAARIVFD-- +>[subseq from] Beta-lactamase n=1 Tax=Methyloceanibacter stevinii TaxID=1774970 RepID=A0A1E3VPD2_9RHIZ +--DLASQFAKIEKKIGGRLGVAVS--GAGLKA-AYHGGERFPMCSTFKLLAVAAVLHRVD +EGDEMLSREIPVPPDAILDYAPVAKEHAGGTMTISELCEAAMVWSDNTAANLILESLGGP +EAATAYVRSLGDTVTRIDRMEPEANVFGPGELRDTTRPRAMLDDMQELFLGDALSPLSRD +RLTEWFVANQTGKDRLRAGLPPTWRVGNRTGTGPHGTSNDVAMAWGEDGQPILIAAFLTG +SKADAAARDNALADVGRAI---- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00045A767A +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKAIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0010553C4E +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGSGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPASTKGKPTIAAATRIVLRAf +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBX8_STEMA +-----ADFAALEKAIGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. PAN_FS17 TaxID=1855351 RepID=A0A1H4SDP0_9ACTN +--ATTDRLRELERQHGSRLGVFAYNVRTRKTV-THRADELFPMCSVFKTLASAAVLRDLD +RDGEFLRRRIHYTEADLPEGSDKTREHLAEGMTVAELCEVAITYSDNGAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYGRLVLDDALNRPDRR +LLTHWLLSNTTSGKRFRAGLPKTWTVADKTGSGSYGTTNNVGVAWTPDGTPVVLSVLSTK +PAQDAAWDDALVAETAALL---- +>[subseq from] class A beta-lactamase n=1 Tax=Luteimonas abyssi TaxID=1247514 RepID=UPI000737B0D1 +-----DALADLERGAGGRLGVALLDTADGRRI-GWRDDERFPMCSTFKALLAGAVLHAVD +HGRADLHHALPVRADDVITHSPYVATRVADGATVADLCRATVTLSDNAAANLLLPLVGGP +AGLTAFLRGIGDPVTRLDRREPELNEAAAGDPRDTTSPRAIVDSLHALLFGDALRAPSRA +VLAGWLIDNRTGDARIRAGTPAGWAVGDKTGTCGSGTAADVAVLYPPERAPLLLAIYAHG +AAISGAPLDALQADIARR----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MUSC 14 TaxID=1354889 RepID=A0A1S2Q318_9ACTN +----EAELNELEQRHGARLGVFARNLRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDHG +-DCAPPDKLIHYPPHDILPHSPRTAEHVDTGMTVADVCAAAIRYSDNAAGNLLLREIGGP +AGLTRFFRSLGDEASRLDRWEPDLNGAVPGDLRDTTTAEALGGSFARLTLGRALAGADRA +RLVGWLKGNTTSGARFGAGLPRDWVLADKTGTGDYGTANDIGVAWTTRGTPLLLTVLSAG +TVQDAPADDALVAEAARILA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. JCM 19046 TaxID=1460640 RepID=W7ZJT7_9BACI +-dDLTAPFSELEDQYDARLGVYALNTGNGQTI-AFNEDERFAYASTHKALAVGVMLQQLS +--IEDLDKQVTFSEAELVTYSPITEQHVETGMSLREISDAQIRYSDNTAANLVFNEINGP +AGFKEALRAIGDDVTEPERMETELNDVNPGETRDTSTPKALAESLYAFSFGDALDKEKQT +LLNDWLIHNTTGDDVIRAGVPDDWVVGDKTGSASYGTRNDIGIIWPPNDEPIVIAVLSSK +DEQDGKSDDALIAEATEAAL--- +>[subseq from] BlaL family class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-1868 TaxID=1463892 RepID=UPI0004C51F93 +--AHEKEFRALEKKFDATLGVYAIDTADGQEI-THRADERFAYGSTFKALQAGAILRKFS +AEADGMDKVVHYGQDAILPNSPVTEKHVADGMSLRELCDAVVRYSDNTAANLLFDQLGGP +KGLNAVLKQLGDHTTSMDRYEQELGSAVPGDPRDTSTPRAFAEDLRAFAVEDALAPNDRE +QLNDWMSGNATGDALIRAGVPKDWKVADKSGQVKYGTRNDIAVVRPPGRAPIVVSVMSHG +DTQDAEPHDELVAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium brisbanense TaxID=146020 RepID=A0A100VXX9_9MYCO +---LDDQIAGLEKRNNASIGVFAANVDSNRTV-AHRADETFAMCSTFKGYAAGRVLQQVD +RGQLALDTRIFIDPSAIVANSPVTEERTGADMSIGELCQAALQHSDNTAGNLLLKLIDGP +PGITAFARSIGDNRTRLDRWETALNSAIPGDLRDTSTPAALGAGYRAMLTGDVLSPPQRQ +QLEEWMRGNET--SSMRAGLPAGWTSADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS +RADDAANLRPLIGELTALVV--- +>[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0009E9AA71 +--AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADELFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Pannonibacter phragmitetus TaxID=121719 RepID=UPI0009E340F3 +--QLAETVAKTESRLNARVGVVLYDTGSGWSW-TNRADERFLMNSTIKTPICGAILSAAD +AGTLTLDEELPVLQSDIVSYAPVTEKKVGQSMPLSELCLATIDMSDNTAANLLINRLGGT +AAVTEFFRSTGDTVSRLDRLEPDLNTFKSGDPRDTTSPAAMAATLEKLLLGDVLSPQSRN +QLTEWMSHGGVTGALLRKTAPEGWYIADKSGSGDQ-TRNIIAMITPPDRAPWIAVIFVSD +VKADFATRNGALQDISAAVID-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Amycolatopsis TaxID=2618356 RepID=UPI00106EDEB5 +----QPDFAALEKAFGARLGVYAIDTGDGREV-AYHADDRFAYASTHKVFNAAAILHRGD +----DLTRTVTIRQSDLVPNSPITEKHIGEQMSLQSVLDAALRYSDNTADNLMFREIGGP +AGLAAELRRLEDTVTHVDRIEPALNETSPGDVRDTTTPRVWAKDLRAVALDSGLPADKQA +VLTKIMRANTTGAHVIRAGVPADWQVADKTGSADYGTRNDIAVLWPPHRAPIVLTVLSDR +PQKDAKTDDKLIAQAAAAVVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=C8CE55_ECOLX +---------------------------------SFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEVDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNR------------- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardiaceae bacterium TaxID=1873463 RepID=A0A431NNZ7_9PSEU +------RVDDLESRFGARLGVWARDTGSGAEV-AHRADERFAFCSTFKMLAAAAVLRDVA +--PDRLDAVVRYSAADLMTSGRVTRDHVATGMTLRELCDAAVRFSDGTAGNLLMREVGGP +AGLTAFARSIGDEVTRVDRTEPELAQGAPGEERDTSSPRALGQDMQRIVLGDVLATDRRD +FLADPLVRNTTGDARVRAGVPAGRRVADKTGTGGYGTANDVAVVWPPGRAPIVVALMSTM +AQRYADVDEALLAEAAGRVMTAf +>[subseq from] Beta-lactamase n=1 Tax=Hephaestia caeni TaxID=645617 RepID=A0A397P7U0_9SPHN +------DLAAIATRSGGRLGVAALDTGSGRRI-GHDQDARYALCSTFKAPLAAAILARVD +AGDIALDDRLTFTDADVLDYAPVVKAHRAGHLTVGEACAGAVELSDNSAANLLLKRIGGP +AGLTRFMRAAGDSVSRLDRYETALNLVGPGEIHDTTTPAAMIGLLGALALGEVLSPSSRA +QLIAWLVAGQTGGALLRAGLPPGWRVGDKTGRSGEGAVNDIAIAWPPRRAPILIASYLYA +PDLSADRANAVHADVARAVAAAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075743DF +--AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVVGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA +QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] class A beta-lactamase n=1 Tax=Agreia sp. VKM Ac-2052 TaxID=123316 RepID=UPI000999A0AB +------AFAQLEQEFDARLGIYALDPDTRAEV-AYRADERFAYASTFKALAAGILLKTVS +--DDELDGLITYDAGDLLPNSPVTEANVDNGMTLRAVAEAAVRFSDNTAGNIMLEHLGGP +EGFTQALRELGDTTSSSDRIETELNSAIPGDTRDTTTPRAFALDLATLLTTDALGAAQQS +QLIDWMTGNATGAELITAGLDAGWSVADKSGAGAYGTRNDIALLWPPSGSPIVLVVMSNR +PTEDADYDNALIARAAEAAL--- +>[subseq from] Class A beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. SID9913 TaxID=2706117 RepID=A0A6B3DHJ7_9ACTN +---LSGRFRALEKRYGARLGVYAHDPRSGRTV-RYRADTLFPQCSLFKTLAAAAVLRDLD +RDGEVLARRIRYTEADLVEGSDHTRENLATGMTVAALCDVAIRFSDNTAANLLLRELGGP +TAITRFARSTGDRVTRLDRWETELNSAEPWRTTDTTSPSAIGRTYARLVLGDALNRCDRS +RLTDWLLRNETSGTRLRAGLPGTWTVADKTGGGPYGTNNNVGIAWTDDGSPLVLSLLSRM +SERDAVKNDALIAGAAAVLAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Phyllobacteriaceae bacterium SYSU D60010 TaxID=2267839 RepID=UPI000E651252 +-qDAAAKLAALEGRHAGRLCVSILDLASGKRV-EHRAHERILMCSTFKALAAALVLSRVD +KGEEKLDRRITFAKKDILPASSVTQAHVGEPMTMAELCEATVTRSDNTAGNLILASFGGP +AGLTEFFRKLGDDVSRLDRIETELNYDGPDDVRDTTTANAMLENLRKLLFTDFLSGPSRS +QLAAWLIATKTGDSRLRAGVPKTWLVGDKTGTNGYGNANDIAVLWPPDRSPLIVTAYCEI +PAIPADERNAVIAEIGRIAAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia SKK35 TaxID=1118156 RepID=M5CMQ1_STEMA +-----ADFAALEKASGGRLGVTVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP +PALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QLADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHAGPAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces dioscori TaxID=2109333 RepID=A0A2P8PXG6_9ACTN +---TVRALAELERTHNARLGVYAHNTATGKTV-RYRADETFPMCSVFKTLTAAAVLRDLD +RRGEFLDLLIRYTEQDLKDGSPVTGRNLAGGMTVAALCHAAMAHSDNAAANLLLRELGGP +TAITRFCRSIGDPTTRLDRWEPALNSAEPWRTTDITSPAAAGRTYAKLALGDALVPRDRR +QLTEWLLANTTSTNRFRKGLPADWALGDKTGTGKYGTTNDVGIAWTPAGAPVVLSVLSTK +PDPDALMDEPLVARAAELLA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00112146AA +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARNQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Neisseriaceae bacterium DSM 100970 TaxID=2052837 RepID=A0A2I7N7M1_9NEIS +----YQQMSKLESTVGGRIGIAVYNTRNKETL-SYRGNERFPFCSTGKVMTVAAILKASE +KESDLLTKIIKYNKADTDKYAPITSKYVAKGMTISELSQAALDYSDNTAMNLLVAEAGGV +GKITDYARSIGDEKFRLDRMEPELNTAIPADNRDTTTPLAMTMSLDKLAFGQSLESNSQA +YLTKWLKANTTGDKRIRAGVPNSWIIGDKTGTGAYGTTNDIGIIWAAKCDPIVISIYYTQ +DQKDAKSNDSVIASATKVAID-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A3E1IK87_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Nocardioides zeae TaxID=1457234 RepID=UPI0013BE2D9D +--AAAARFAALERQYDARLGVVALEVDTGRVV-AHRPDERFAFASTVKALQVGALLRTAT +--EADLDRTVRWTEDDLVTYSPVTEQHVADGLTVRELADAAVRYSDNTAANLLFDELGGP +AGLTAELRRIGDTTTTSVREEPDLNTAVPGDVRDTSTPRALARSLASYTLGCVLAPDRRA +ELVDLLVRNTTGDALVRAGAPDGWTVGDKTGSAAYGTRNDIAVAWPPNRSPVVIAVLTSG +DEADDPTHDALVADATRVTF--- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura mexicana TaxID=134959 RepID=A0A238ZQF1_9ACTN +------RFAALERRHGARLGVYATATGTGAEV-AYRADERFAFCSTFKALAAAAVLHGNP +--LGHLDERVTYTRADVNSISPITKDRVDTGMTIRELCEAAVRHSDGTAGNLLMRDAGGP +ARLTAYLRGLGDTVSRMDDYEPELNRIRPGDPRDTTTPRAIAADYRAIVLGDALEPAKRA +LVRGWLERSATGAERVKAGLPEGWRTASKTGTGDYGRANDIAVVWPPRGAPLMVAVMSDR +PGYDTPPKNALIAQATELVVS-- +>[subseq from] Class A beta-lactamase n=1 Tax=Methylobacterium mesophilicum SR1.6/6 TaxID=908290 RepID=A0A6B9FGR3_9RHIZ +-----SDLAAIEHRLGGRLGVAAYS-AERALL-RHRADERFPLCSTFKVLAVAAILARVD +AGSESLDRTVRYGAQDLLSYAPVTRKALEAALSVSDLCAAALEWSDNTAVNLLLVPLGGP +AGQTAWLRGLGDPVTRLDRTEPTLNEAIPGDSRDTTTPEAMQATLGRILLGSVLSPSSRA +RLEGWMVASQTGFKRLRAGLPKDWPVGDKTGSGDNGSFNDVAILRPPGRAPVIAAVYMTG +ATAPAKVVESAYAEIGRLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F1A10 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +AGADAAPRADVVAEAARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID8111 TaxID=2706100 RepID=A0A6B3ANJ4_9ACTN +---LSGRFRALEKRYGARLGVYAHDPRSGRTV-RYRADTLFPQCSLFKTLAAAAVLRDLD +RDGEVLARRIRYTEADLVEGSDHTRENLATGMTVAALCDVAIRFSDNTAANLLLRELGGP +TAITRFARSTGDRVTRLDRWETELNSAEPWRTTDTTSPSAIGRTYARLVLGDALNRCDRS +RLTDWLLRNETSATRLRAGLPGTWTVADKTGGGPYGTNNNVGIAWTDDGSPLVLSLLSRM +SERDAVKNDALIAGAAAVLAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DFD63B +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVVHQKP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A2L1J0Y0_PSEAI +----------------------EMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A106CSX4_9BURK +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGSPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A4Q6ZL72_KLEPN +----------------------------------------FEMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F5611 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Curvibacter delicatus TaxID=80879 RepID=UPI00082985EA +----ALALQALEARSGGRLGVAIRDTGSGAQL-LHRADELFPLCSTFKLLLAAYVLHLVE +QGAEGLERRVVYPASALVAHSPRTAPRTGDGMTVAQLCEATLVISDNTAANLLLARHGGP +QALTAWLRGLGDTQTRLDRWETDLNSALPDDPRDTTTPGAMLETMDKVLLGSVLGPVSRR +QLQTWIRGNLTGDHALRAGFPSGWVVGDKTGSGDRGTRNDVAIAWPAERAPLLVASYLTG +AQITPAQRDGVHAEVARLA---- +>[subseq from] Class A beta-lactamase n=1 Tax=Saccharopolyspora sp. 5K548 TaxID=2530386 RepID=A0A4R5BKT8_9PSEU +--------AELERRYDARLGLFARNVATGRTV-AHRADERVALCSTFKVYASAALLRAHG +LAGGYFDRVIRYDAGQLVKNSPITETRVGTGMTVGELCAAAVQHSDNTAANLMLRELGGP +QAITEFARAIGDPMTRLDRWEVELNTAIPGDERDTSTPRALGDGLQRLLLGDVLGPAERD +RLTGWMLGSATGAARIRAGVPSSWRTADKTGGGSYGVANDIAVTWTDTGAPIVISLLTGR +PREHDTANNALLADAARLVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas daejeonensis TaxID=659018 RepID=A0A0R0EDG7_9GAMM +----TDDFAALEKRSGGRLGICLWHPASGARF-GHRMDERFPMCSTFKFLLAAAVLHRAG +RGELSLDRRVPVRAADILHHSPASTRHVGKDMSVRDLCRATLTISDNAAANLLLPLIGGP +AGLTAFLRAQGDALTLCARHEPELNLFAPGDPRDTTSPAAMAGNLQRFVLGDALEPASRM +QLADWLIDNQTGDARLRAGLPRGWRVGDKTGSGYDGITNDIAVLWPEQGAPWLLACYLQG +STLGDDDRNGILRRVGELAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces curacoi TaxID=146536 RepID=A0A117P5D1_9ACTN +--SATAEFRSLEREFDARLGVYALDTGTGRSV-GYRADDRFAYASTFKALAAGAVLRKFG +--TDGMDRVVRYSRDDLVADSPVSENFVKTGMSLRGLCAATLWYSDNTAVNLLLDELGGP +DGLEKVLEEFGDDVTEMDRYEPDMSEGAPGDIRDTSTPRAMAGSLRTFLLGDALKADERE +LLRQWMTTNMTGRTLIRAGVPDGWDVADKSGTAGYGGRNNIAVVWPDDGNPIVMAVMSSR +DKQGAERNDALLAKAATVAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium simiae TaxID=1784 RepID=A0A5B1BKM7_MYCSI +--DLSGRFEPLERQYDARLGVYVPAASPSAAI-AYRADERFAFCSTFKAPLVAAVLHQYP +--LTHLDKVITYSSDDIRSTSPVTQQHVQGGMTIGQLCDAAIRYSDGTAANLLLADIGGP +AAFTEYLRSLGDQVSRLDQEEPELNRDAPSDERDTTTPHAIALVFQQLVLGDALAPDKRA +MLIDWMARSTTGAKRIRAGFPADWKVIDKTGTGDYGRANDVAVVWSPTGVPHVVAIMSDR +AAYDALPNEALIADAAKYIAD-- +>[subseq from] Uncharacterized protein n=1 Tax=Achromobacter sp. RTa TaxID=1532557 RepID=A0A095VUS7_9BURK +--ALNQALAQLEASSRGRLGVALLDTASGQTA-GYRADERFLMLSSFKTLAAAYILARAD +RGEDRLDRRIPITQADLQEHAPVTRLHVGPQMTLAGLCEATITTSDNTAANLMHRSYGGP +QALTRFIRSLGDTVTRHDRYEPELNRLHAGEPLDTTSPRAMTGTLDTLLFGQALKPQSRQ +LLQSWLLANTTGGKRLRAGFPPDWKVGEKTGTYSKVGSNDAGFAQAPGGAPIVVSAYLET +TGIPMPERDRIIAEVGGLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium nanningense TaxID=1325118 RepID=A0A4Q0RUT1_9BRAD +------EFESYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARID +RGEEQPTAMIPYGKDDLLEYAPAAKQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTTFWRSIGDSASRLDHNEPELNRSPPGNPQDTTTPMAMAGNLRRLVVGEALSPASRA +LLRDWMENCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVVWPKPETPILIAAYTQG +GTPKPAQIEAAFARIGRMAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium porcinum TaxID=39693 RepID=UPI0011958D9B +----DDQIADLERRHNALIGLYASNLDSGRTL-AHRPDEMFAMCSTFKGYAAARVLQMVG +RRQISLDNRVFVDREAIVPNSPITETHVGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP +PGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSSPAALAAGYRQVLAGDALSPPQRR +QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS +QADDADNLRPLIGELTAAV---- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011205D71 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Xanthomonas retroflexus TaxID=305959 RepID=UPI000B448320 +---AAADFAALEKACSGRLGVTLLDSAGGRRF-GHRQDERFPLCSTFKSVLAATVLKQAE +RDAALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA +GTISFDQRAAVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. SKA14 TaxID=391601 RepID=B8L6C1_9GAMM +-----ADFAALEKASGGRLGVNVLDTGSGRSIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEQDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHSGPAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase AXC-5 n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A5C0PY34_ALCXX +--AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADELFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVRGYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET +TAVPMEERDRCIAEVGRLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A088DJ21_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLTGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005E4E356 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLPQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011238C17 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S054 TaxID=1394599 RepID=A0A0I9QQQ6_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A088DK81_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=3 Tax=Vibrio TaxID=662 RepID=A0A072F0N7_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111D0F98 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011220718 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0009579BE0 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces globosus TaxID=68209 RepID=A0A344U1U5_9ACTN +------ALRALEREYGARLGVYAWDTATGRTA-AYGADALFPQCSLFKTLAAAAVMRRFD +RDGEYLAKRIHYTQADVTRGGEITEENIAAGLTVAELCSAAIAHSDNTAGNLLLEELGGP +TAITSFCRSLGDPVTRLDRWEPELNSAEPWVSTDTTSPRAIARTYARLVLGDALRPRHRE +LLTGWLLGNTTSRDRLRAGLPADWAVADKTGAGSYAVNNNVGIAWPPGRPPVVIAVLSTK +PEAAAQREDSLVARAAGLAVR-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. MYb57 TaxID=1827305 RepID=UPI000CF72804 +----AADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDPALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA +GTISFEQRAAVLAQVGRIA---- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio rotiferianus TaxID=190895 RepID=UPI001110F374 +--KLNEDLAAIEQHIGGRIGVSVWDTQNDEHW-DYRGDERFPMMSTFKTLACATMLKDMD +SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMINTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPIYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] Class A beta-lactamase n=2 Tax=Mycobacteroides abscessus TaxID=36809 RepID=A0A4U6NVG0_9MYCO +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPSLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] Beta-lactamase n=2 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00027FCDEB +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEAPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758097D +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013DCDFB8 +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. QMT-12 TaxID=2717324 RepID=UPI00141554BF +htALTRRLRNLERERSARLGVFAQDMATGRTV-VHRGHELFPVCSVFKTLAVAAVLRDLD +TDGTYLSRRIRYTKQDVVRHAPITGENLARGMTVEALCAATITHSDNTAANLLLAKLGGP +SSVTRFCRSVGDFVTRLDRWEPDLNSAEPDRTTDTTSPYAVGRTNARLILGDALDPADRD +RLAGWLLANTTGGKRLRAGVPGDWSVAEKTGTGAYGTTNDVGVAWRPGRGSVVLSVLSTT +QDPDAPADDELIARAAALIAA-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium lacus TaxID=169765 RepID=A0A1X1YXR3_9MYCO +-qDLAARFAELEQKHQARLGVYVPATGPTAEI-AYRADERFAFCSTFKAPLVAAVLHRGP +--LTRLDRVITYTSDDIRSTSPVTQQHVQDGMTIKQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDAVGRLDQEEPELNRDPPGDERDTTTPHAIALVYQQLVLGDALNTDKRA +MLTDWMARSTTGAKRIRAGFPADWRVVDKTGSGDYGRANDVAVVWSPSGDAHVVAVMSDR +VAYDAEPSDALVAAAATCVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. MUSC 14 TaxID=1354889 RepID=UPI0009A1077F +----EAELNELEQRHGARLGVFARNLRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDHG +-DCAPPDKLIHYPPHDILPHSPRTAEHVDTGMTVADVCAAAIRYSDNAAGNLLLREIGGP +AGLTRFFRSLGDEASRLDRWEPDLNGAVPGDLRDTTTAEALGGSFARLTLGRALAGADRA +RLVGWLKGNTTSGARFGAGLPRDWVLADKTGTGDYGTANDIGVAWTTRGTPLLLTVLSAG +TVQDAPADDALVAEAARILA--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis indica TaxID=436663 RepID=A0A239DI11_9SPHN +---IARKLAALERQAGGRLGVCFRDAASGRSA-GHRVDERFAMCSTFKWPLSAVVLKAVD +DGKLALDRRVPYGKADLIPNSPVTSKRVGEGLTVAELMEATITTSDNAAANLLLPLVGGP +EAVTRQFRAWGDPVTRLDRTEPALNSVAPGDVRDTTTPGAMAALLDTILLGDVLSPASRT +RLVDWGVATTTGTRRLRAGIPADWRFGHKTGTATMNKYNDIAIAFPPQGAPLLITAYYEG +PVASRAEDEAVLASVARLAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. BK227 TaxID=2512162 RepID=UPI001046BA30 +---AEPDWAAIERRLGGRLGIAAASVD--RVLaAYRADARFPMCSTFKALAVAAVLARVD +VGRETLDRVVSYGLGDLLSYAPVTRKALEAGMRVADLCAATLIWSDNTAANLLLADLGGP +EVLTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRVLLGTVLSPDSRA +RLEAWMVACETGRKRLRAGLPPDWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTE +STASPDTCAAAYAEIGRLIA--- +>[subseq from] Beta-lactamase 3 n=2 Tax=Bacillus sp. THAF10 TaxID=2587848 RepID=A0A5P9HT78_9BACI +----KIYFKELEKEYDAKLGVYALDTGSNRKV-SYRADERFAYASTHKVLAVGVLLMNRT +--IDELNETIKYTKEDLVNYNPVTEKHVENGMTLKELSDASIRYSDNTAGNLILEAIGGP +KGFKESLRKMGDHVTEPERMEPDLNDVKPGETRDTSSPKALAESLQAFTLGSVLPETKRN +LLIDWLKRNTTGDNLIRAGVPKGWTVGDKTGGAN-GIRNDIAILWLPDGAPIILVVLSSH +EKANSENVDELIAKATEEAVK-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001121499D +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TNLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. MSMB1072 TaxID=1637871 RepID=UPI00075CA083 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSSDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKATPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAVLWPPSRAPIVMAVSFTQ +PEAAAAARADVVAAAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0003BB5517 +---LADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKAIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI0002ADF6EB +--KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLRDMD +DEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] Beta-lactamase class A n=1 Tax=Fulvimarina pelagi HTCC2506 TaxID=314231 RepID=Q0G4Z1_9RHIZ +-------AAKLEDRLETRVGVFVLDTGTGETW-EHRADERFPMASTFKSFACSALLDKAA +KGSLALDDTVAVEVSDLVTYSPVTEKRVGSRLSLREACEATLRTSDNTAANIVLEALGGP +QAVTDFMRSIGDDATRLDRYETALNEARPGDARDTTTPRAAAESLRTLLLDDGLGASDRQ +LLGNWMRSNEVAGPLLRAGIPDTWIAADRSGAGGFGTRGVTAVLWPPEHAPFVVAAYLTG +REIPMESRNEALAEIGRAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI00119E5BA7 +-----GELADLERRYGARLGVYARNVRTGRVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMADVCAAAIQYSDNAAGNLLLRRMGGP +GGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALATSIERLALGRALAAPDRE +RFVGWLKGNTTSGARFRAGLPAGWTIADKTGTGDYASANDLGVAWTTRRTPVVLAVLSTK +EGKDAPVDEALIAEAARIAAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. Ec3.3 TaxID=189753 RepID=UPI0004030330 +------ALETYERESGGRVGFYAENLSSGKKL-GWRADERFVMCSTFKASLAACVLARVD +RGEDQLSAMIGYGRDDLLDYAPVARENLSKGMSVADMCKASVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPSAMAGNFRRLVLGEALSAASRA +QLTEWMVNCKTGAKRLRAGLPGTWRIGDKTGNNGKDASGDIVVAWPKPDTPILIAAYTQG +GTPNAAQIDTVFASIGKTVAA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora flava TaxID=95161 RepID=A0A1I6REP1_9PSEU +-------LVELERRYDARLGLFARNAATGRTL-AHRADERAALCSTFKVYASAALLRAHG +LAGGYFDRVIRYDAGQLVEYSPITETRVGTGMTVGELCAAALQHSDNTAGNLLLRELGGP +RAITDFARSIGDPVTRLDRWETELNTAVPGDERDTSSPKALADGLQALLLGDVLGAPERD +LLTRWMLGNTTGDARIRAGVPGDWRTADKTGGGSYGVANDFAVTWTGTGTPIVISLLTGR +PRAEDAANNALLAEATRLVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758BFC1 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Bradyrhizobium betae TaxID=244734 RepID=A0A5P6P4P5_9BRAD +------ELESYERETGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGKADLLDYAPVAKQNLATGMSVAEMCKAIVELSDNSCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSQPGDPRDTTTPAAMAGNLRRLVTGEALSPSSRA +QLTEWMVGCKTGANRLRGGLPASWTIGDKTGNNGKDASVDIAVAWPKPAAPILIAAYTQG +GTPTAAQIEAVFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces afghaniensis 772 TaxID=1283301 RepID=S4MYE4_9ACTN +------RLADLEREYGARVGVYALATGTGATA-VHRADERFAFCSVFKALAAAAVLHHRS +--LGGLDRRVTYTRADLKSTAPVTGRHVATGMTLRELCDAAVRYSDGTAGNLLMRDLGGP +AKLTAYLRGLGDTVSRMDHYEPELHDVRPKDPSDTTTPRAVAADFRELLLGTALPAGERA +LLTDWLSHNATGARRIRAGLPKGWQVADKTGTGNYGRANDIAIVRPPRTAPLVLAVMTDR +PGYDAEPSNALIAEATART---- +>[subseq from] Class A beta-lactamase n=3 Tax=Burkholderia TaxID=32008 RepID=A0A118G180_9BURK +--AAQAELAALEKASNGRLGVAALDTSSGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTAFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMTGGARGATGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIAT--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001121E573 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. ZJ1307 TaxID=2685870 RepID=UPI00140E3646 +--------VALEERYDARLGIFAIDTHTGETV-EHRADERFAYASTYKALAAAALLARTG +--ERRWEEVVAYDADDLVTYSPVTEQHVGTGLSLQRIAEAAVRESDNTAGNLLLDELGGP +AGFQQALRELGDDVTVAARRETALNDTAPGDRRDTSTPRALAQVLQRYAVGDALRRPARR +TLLSWMRGNATGDTLVRAGVPDGWRVADKSGAAAYGTRNDIAVIEVPGRAPVVMAVFSDR +GTPDAEYDDALVAEAARVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacterium casei TaxID=33889 RepID=A0A449DBP2_9MICO +--EADSAFTQLEDDFDARVGVYAVDLDTGREL-AWRGDERFAYASTIKALASAALLDEVG +--TDGLSKRVAISEDDIVSHSPVTETKVGGTMTLAELCEAAMTQSDNGAANLIFTELGGP +AALDERLNDLGDTGTTVSRTEPGLNEAKPGDPRDTTTPRASAGNLREYVFGGALEDDEAT +TLTDWMKATQTGDTLIRAELPEEWTVGDKSGTGYYGSRADLGIVWPGDGGPIIISVLSAK +DEKDAEADDRLISGAAAIAVE-- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio owensii TaxID=696485 RepID=UPI0003A99C96 +--KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD +SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTATNIVLRSIGGP +HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S020 TaxID=1394567 RepID=A0A0I9QPR9_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLTGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Patulibacter americanus TaxID=588672 RepID=UPI0003B5356F +--QARPAFARLEREHTARLGVIATDTGTGRTV-SYRAGERFAFASTSKALTAGLLLQRAS +--DRDLRRVVRYRPSDLLEYAPVTRRHVATGMTLRGLTIAALQHSDNTAANLVMRELGGP +RGVERGLRALGDRTTEVERTEPTLNTAIPGERRDTTTPRAIARDLRSFVLGTALTPPRRA +LLARWMVGNTTGGKYVRAGVPAGWVVADKTGSAGYGTRNDIAVVWPPQGRPIVVAVLSDR +RRPSRASDDALIARATRTAVR-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111FE2AB +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNVLSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6B8GN88_STEMA +---AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDAALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRASGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA +GTISFEQRAAVLAQVGRIA---- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas indicatrix TaxID=2045451 RepID=UPI000C19BDE0 +---AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDAALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRASGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA +GTISFEQRAAVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia hospita TaxID=169430 RepID=UPI000DEFD2AA +----RGRFEKLEASSGGRLGVAALNTADGSYV-SYRESERFPMCSTFKLLVVALVLKRSM +AERSLLDERVRYGDADLVANSPVTKRRAGEGMTIGELCAAALQHSDNTAANLLLTAVGGP +EVLNQFALSIGDEWFDLLRGEPEVNGSVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE +QLKAWMLGNATGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG +VMKQTLPRDEVVAEAARIVFD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces lavendulae TaxID=1914 RepID=BLAC_STRLA +--DVLRQLRALEQEHSARLGVYARDTATGRTV-LHRAEERFPMCSVFKTLAVAAVLRDLD +RDGEFLATRLFYTEQEVKDFGPVTGENLAAGMTVERLCAAAICQSDNAAANLLLRELGGP +EAVTRFCRSVGDRTTRLDRWEPELNSAEPGRLTDTTTPRAIGATYGELVLGDALAPRDRE +RLTGWLLANTTSTERFRKGLPADWTLGDKTGGGAYGTNNDAGVTWPPHRPPVVMVVLTTH +DRPDAVADNPLVAKTAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. S1 TaxID=718288 RepID=UPI000EF7A4CC +---HRREFRALESAFDARLGVYAIDTGTGREI-AYRDRERFPYASTFKALAAGAVLRE-- +EGLGGMERVVRYTKEELVEPSPVTEKHVGTGMTLDALADAAVRYCDNTAGNLLFEELGGP +KGLQAVLRSLGDGVTRMDRIEPELGDWKPGEVRDTSSPRALAGDLRAFVLGDVLRAPERE +RLTTWLKTNLTGDETIRAGVPDTWVVGDKTGTATYGGRNDMAVVWPPDGAPIVMAILSTR +SGREAEPDNRLIARAASVVA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Haloactinospora alba TaxID=405555 RepID=A0A543N9E8_9ACTN +---HEEEFRQLEEEFDARLGVYAVDTGSDREL-AHRAGERFAYTSLFKPLACGALMERRS +-LSELKEEVVTYGADDLVEYSPVTKENVDDGMTLMEVCDAAMRYSDNTAGNLLFEEFGGP +EGLQEALEGIGDDTTRMERLETELNEAVPGETRDTSTPEAMTANLREYTLGDTLNEDERD +VLSEKMRNNTTGDDLIRSGVPDGWEVGDKSGAGGYGTRNDIGLLWPPEGDPIVLAVMSSK +DEEDAEYDDALVAEAAGVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis alba (strain ATCC BAA-2165 / BE74) TaxID=1205910 RepID=J7L1V5_NOCAA +--DVEAEFEALEAEYDTRLGVYALDTGSGEEV-EFREDERFAFASTFKSLLAGVVLSENS +--LEEMERVITYDEDALVSHSPITEENVGTGMSLLELCDATVRFSDNAAANLLLEELGGP +EGFTESLEETGDDVTTLDRYETDMSAAVPGDERDTSTPEALAGSLEAFTLGDVLPEDRRE +VLVDMLVRNMTGDAVIRAGVPEGWVVGDKTGTGGYGTRNDIAVVWPEEGDPIVLAVLSTM +EVEDAEPQDSLIAEATEVVVE-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111D561E +--KLNENISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium miluonense TaxID=411945 RepID=UPI001199A454 +----EERLAALESKHPGRICVSILDMASGRRI-EHRAGEHILMCSTFKALAAALVLARVD +KGEEKLDRRIRYSEGDIIGGSPATKLRVGDGMTVAELCAAAVTLSDNAAANLLLASFGGP +KALTAFCGSLGDDLTRLDRTEPTLNYDTPDDQRDTTTAAAMLENLRRLLFTDVLTASSRS +QLAAWLITNKTGDARLRAGVPKDWLVGDKTGTNGAGNANDIAVLWTSKRAPIIVTAYCEI +PSISADERNAVIAEIGRIAA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI000D7364EF +--KLNENISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Lentzea jiangxiensis TaxID=641025 RepID=A0A1H0PDJ5_9PSEU +--TVTGRLRELERQHNARLGVFATDTGTGRTV-LHRADELFPMCSTFKTIAAAAILRRDR +-DGSLLRKVITYTQSDVDKHAPVTGRNLANGMTVAALCEATITHSDNCAANLLLRELGGP +TAITRFSRSIGDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGQSYARLTLGHALNPNDSD +QLTNWLLANTTGGNRIRAGLPSAWRWGDKTGTGKYGTTNDAGIAFPPGRAPIVIAVLSTR +QDPTGGADEPLLAETAELVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DF8F2E +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRVDERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium wuzhouense TaxID=1986026 RepID=UPI000D9D283C +----TAAARQVESRLGARLGLMVVDTETNRQW-QYRSGERFAMASTFKALACAALLD--- +AGTQLLSRDIKIEAKDLLAHAPVTSKRVGTRMTAGDLCAATLSTSDNTAANLVLSTLGGP +KRVNAFLRSIGDTVTRLDRMEPALNEATPGDPRDTTTPEAMARTIGELLIGDGLAPLARR +QLTRWMEANAVADGLLRAGVPRDWRIADRTGAGGHGTRGIVAVMWPPGKKPVVAAIYLTE +TEASLATRDAAIAELGRVLA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011224F9F +--KLNEHISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARNQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B268A +---AQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-3213 TaxID=1463846 RepID=UPI0005650416 +----QPDFAALEKAFGARLGVYAIDTGDGREV-AYHADDRFAYASTHKVFNAAAILHRGD +----DLARTVTIRQSDLVPNSPITEKHIGEQMSLQSVLDAALRYSDNTADNLMFREIGGP +AGLAAELRRLEDTVTHVDRIEPALNETSPGDVRDTTTPRVWAKDLRAVALDSGLPADKQA +VLTKIMRANTTGAHVIRAGVPADWQVADKTGSADYGTRNDIAVLWPPHRAPIVLTVLSDR +PQKDAKTDDKLIAQAAAAVVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A6BA4D +-----DELASLEKEFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S024 TaxID=1394571 RepID=A0A0I9QQR1_VIBPH +--KLNEDISIIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=A0A418LAY6_9MYCO +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPKQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis decaplanina TaxID=208441 RepID=UPI000A005A30 +-----ADFERLERTFGARLGVYAVDTATGREV-AFRAEERFAYASTHKVFSAGGVLQRTP +--VADLDRTVTYGRKDVVADSPVTEKHVATGMPLRAVMDATLRYSDNTGGNLLFRELGGP +EGLNAVFRGIGDTTSHADRIEPALNDTAPGDNRDTSTPRALAVSLRAFALGDALPEDKRK +ILVDMMRANTTGDQNIRAGLP-GWPVADKTGTAAYGTRNDIGVVWPPNRAPIVISVLTDR +PDKDAKIDNKLLAEATAAAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Saccharothrix sp. CB00851 TaxID=1835005 RepID=A0A1Q4XLJ1_9PSEU +-----DHLVELERKFDARLGVYAVATGTGTTV-EHRADERFAFCSTFKGLAAAAVLHRHP +--LSHLDTVVTYTEADLMASSAITRQHVATGMTIRQVCDAAVRHSDGTAGNLLLRDLGGP +AGLTAYLRALGDTVTRADRFEPHITTAVPGDPRDTTTPRAIGTDYRRIVLGDVLPPDQRA +FLRDLLERNATGTLRVRAGVPRGWTVADKTGTGDYGTVNDIAVVWPPDTAPLVVSIMSSK +AAADAGYDQALLAEAAAYVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI000F628191 +----HRRLSELEREYGARLGVYALATGTGATV-VHRADERFAFCSAFKGLAAAAVLHGNP +--LSHLDTVVTYTEDDLMKHSPITGKHVSTGMSIRRLCDAAVRYSDGTAGNLLLRDLGGP +GKLTAFARGLGDPVTRMDRTEPAITQATPGDPRDTTSPRAFGTDYRKLVLGTVLPADKRE +FLRDLLVRNATGAQRIRAGVPKDWVVADKTGTGDYGTLNDIAVAWPTGSPPLVISIMSSK +PAKDAAYDQRLLARAAEYVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S146 TaxID=1394680 RepID=A0A0I9QQ17_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHSLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis keratiniphila subsp. keratiniphila TaxID=227715 RepID=A0A1W2M0D0_9PSEU +-----ADFEQLERTYRARVGVYAVDTATGREV-TFRADERFAYASTHKVFSAGGVLQRTP +--IAELDRTVTYGKQDLVVNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP +EGLNAVFRGIGDTTSHADRIEPELNDTFPGDLRDTSTPRALAVSLRAFALGDALPEDKRK +ILVDMMRANTTGDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVVSVLTDR +PDKDAEIDNKLLADATAAAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCSS17_008 TaxID=2175647 RepID=A0A2W2A8K8_9MICO +--ATAREYAALEQRYDARVGVVAIDTADGRAV-GYRSEERFAFASTNKAFIAAAVLDASS +--ADDLDEVVRYDRGDLLEYAPVTRRHVDEGMTLRALVDAAVRESDNTAANLLVERLGGV +DGVTRWLRGIGDDVTRVDRVEPDLNTATPGDPRDTTTPAQSSADLRAVLLGDALDPDDRA +LLRSAMTGTTTGDGTIRAGVPGGWSVADKTGTASYGVRNDIAVLRQPGRDPVVLVVFTAQ +DREDAEPSDALVAAATRVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SUK 48 TaxID=2582831 RepID=UPI00129BDA56 +------ELADLERRYGARLGVYARNTRTGRVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMDKVIHYPPHDLLPNSPRTQENQATGMAMADVCAAAIQYSDNAAGNLLLRQLDGP +AGLTRFFRSLGDDVSRLDRWEPELNTAIPGDPRDTTSPEALAASIERLALGRALAAADRE +RFVGWLKGNTTSGARFRAGLPEGWSIADKTGTGDYASANDVAVAWTTRRTPVVLAVLSTK +EGKDAPVDEALIAEAARIAAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007597147 +--AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNETAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA +QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007544EB4 +---AQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptosporangium canum TaxID=324952 RepID=A0A1I4DEW3_9ACTN +--RARKELRTLEASFKGRIGAYAVDTATGKTV-TYRSGERFPLLSTFKAIAAAAVLHKAR +TDPGLLNKVVHWTSAELQEHSPGTEKHVQDGLTVARLCEAAITRSDNTAANMLLKQIGGP +AGLTAYFHTLKDPVSRLDRWETELNNWSPKEKRDTTTPASMGRDLRAVTTGDALDAKDRE +RLNAWLIANKTGDARIRAGLPKTWTVGDKTGTNSYGAGNDVAVVWPGKSAPIIMSIYTNR +RAADAPADDKVIADTAAILA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) TaxID=83332 RepID=UPI00073339E9 +---LADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVATGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELARDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S141 TaxID=1394675 RepID=A0A0I9QQQ8_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNKIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754E4C2 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDMLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00066EFFC0 +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium peregrinum TaxID=43304 RepID=UPI0007EA6CED +---VDDQIAELERRDNALIGLSATNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMVG +RGQISLDNRVFVDPEALVPNSPVTETHAGSEMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAIGYREILVGDALSPPQRR +QLQDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPNGQRLLLAVMTRS +QADDPKADNPLIGELT------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC 05379 TaxID=2203207 RepID=A0A429GYR9_9ACTN +--ATTDRLRLLEQQHGARLGVFAYNVRTRRTV-THRADELFPMCSVFKTLASAAVLRDLD +RDGEFLRRRIHYTEADLPKGSDKTREHLAEGMTVAELCEVAITYSDNGAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYGRLVLDDALNRPDRR +LLTHWLLSNTTSGKRFRAGLPKTWTVADKTGSGSYGTTNNVGVAWTPDGTPVVLSVLSTK +PAQDAAWDDALVAETAALL---- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00092942F9 +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVTRMDRTEIQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] Beta-lactamase n=1 Tax=Vibrio owensii TaxID=696485 RepID=A0A3G2Q5L6_9VIBR +--KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD +SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] Beta-lactamase n=3 Tax=Vibrio TaxID=662 RepID=A0A0C1Z8C8_9VIBR +--KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD +SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio owensii TaxID=696485 RepID=UPI00104B1DAC +--KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD +SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. MOS002 TaxID=2133947 RepID=A0A2T2QU87_9BRAD +--DAQPELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEDQLAAMVPYGKADLLEYAPVARQNIAVGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLLTGEALSSTSRA +QLTEWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAAAWPKDAAPILIAAYTQG +GTPTAAQIETVFAGIGRLVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075A5E83 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Nitrincola sp. KXZD1103 TaxID=2614693 RepID=A0A5J6LI20_9GAMM +---LLSELKRIESHLDARIGFAAHDTETGMRW-EYNADQRFPLSSTFKTLACAALLQRVD +TGSEQLTTSVSVSSSDLVTYSPVLEEYADTRITLFELCEATMTTSDNTAANLILQSLGGP +ENVTDFARQLGDKVTRLDRWETDLNQAVPGDERDTTTPNAMVSNLE-LLLGNVLSLESKR +YLQTWLVNNKVADGLFRSSMPSDWIIGDRTGAGGFGSRSITAVIWPAEREPVFVAFYITE +TTASFEERNAAIAQLGRVLIE-- +>[subseq from] Beta-lactamase n=1 Tax=Pannonibacter phragmitetus TaxID=121719 RepID=A0A378ZTC3_9RHOB +--QLAETVAKIESRLNARVGVVLHDSGSGWSW-TNRADERFLMNSTFKAPLCGAILAAAD +AGTLSLDEELPILRADILSYAPVTEKKVGQSMSLSELCLATIDMSDNTAANLLINRLGGT +EAVTEFFRQNGDTVSRLDRLEPDMNTFKAGDPRDTTSPAAMSAALEKLLLGDVLSPQSRN +QLIEWMSHGGVTGALLRKTAPEGWHIADKSGSGDR-TRNIIAMITPPDRAPWIAVIFVSD +VKADFATRNAALQEISAAVI--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001124559C +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPEGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111E554E +--KLNDDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0007647C6F +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISAVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] LAP family class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI000BB6BFF9 +---VTDTIQSTEDHIKGRVGFTEIDFLSGKVLsSHRREERFPMMSTFKVLLCGAILVRVD +KGLEQLERRITYNKHDLDDYSPLTSQHIADGMTVSEFCNAAITTSDNTAANLLLSTIGGP +EGLTHFLRSTGDSYTRLDRHEPSLNEAKPGDERDTTTPAAMAQTLQKLLNESVLTEKSRK +KLISWMQEDKVGGPLFRSVLPAGWMIADKTGAGDHGSRGIVALLGPGGKPSRIVVLYITN +THSSMNELNEHIAGIGDSVIKNw +>[subseq from] class A beta-lactamase n=1 Tax=Achromobacter sp. RTa TaxID=1532557 RepID=UPI0009DE03C7 +--ALNQALAQLEASSRGRLGVALLDTASGQTA-GYRADERFLMLSSFKTLAAAYILARAD +RGEDRLDRRIPITQADLQEHAPVTRLHVGPQMTLAGLCEATITTSDNTAANLMHRSYGGP +QALTRFIRSLGDTVTRHDRYEPELNRLHAGEPLDTTSPRAMTGTLDTLLFGQALKPQSRQ +LLQSWLLANTTGGKRLRAGFPPDWKVGEKTGTYSKVGSNDAGFAQAPGGAPIVVSAYLET +TGIPMPERDRIIAEVGGLVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. LA-2-3-30-S1-D2 TaxID=1637862 RepID=A0A1B4EU91_9BURK +--AAQAELAALEKASNGRLGVAALDTSSGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTAFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMAGGARGATGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIAT--- +>[subseq from] carbenicillin-hydrolyzing class A beta-lactamase CARB-46 n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0004D9B684 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDEATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI0004CC1FB3 +hpAATRRLRDLEQEHQARIGVFAVNLTTGASL-LHRAHELFPICSVFKPLAVAAVLRDLD +HDGTELSRRIHYTESDVTKHAPITKLHVATGMTIRELCDATIRFSDNCAGNLLLRELGGP +TAVTRFCRSLGDPVTRLDRWEPELNSAEPGRRTDTTTPYAIARTYRRLVLGSALDHPDRA +LLTDWLLRNTTSVERFRKGLPKDWKVADKSGGGSYGTSNDVAIAWTPDGAPIVLALFTHK +PTQPTASGD-------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=C8CE54_ECOLX +---------------------------------SFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEVDKVAGPLLRSALPAGWFIADKSGAGERGSSGIIAALGPDGKPSRIVVIYTTG +SQATMDERKRQI----------- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075C793D +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +AGADASPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Alcanivorax dieselolei (strain DSM 16502 / CGMCC 1.3690 / B-5) TaxID=930169 RepID=K0CJE6_ALCDB +--ALSRRCREWERRHGGRVGVAVWHLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD +RGEESLDRRLLVSRKDLVGWSPVTEKRTGEGMTVAQLCEAAVAWSDNGAANLLIKGFGGP +GALTEFLRKSGDPVTRLDRLEPELNGYDANKESDTTSPAAMLGTLHRLLFGEVLSAQGRA +QLAAWMIANKTGDRRLRAGFPADWLVADKTGTSGLGYSNDIGVAWSPQRGAVLVTVYCEM +PKAEAGVRDRIIAEVAEMV---- +>[subseq from] carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013D32931 +------------------------------TV-SYRAAERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005E29FDD +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAGLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGDDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus TUMSAT_H10_S6 TaxID=1441612 RepID=A0A0I9QPR6_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDNATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007593C30 +--AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVAAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCMAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA +QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075A6B06 +--AAQSQLDALEQASNGRLGVAALDTANGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB49_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGA------ +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00045B541D +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGHTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. CCH5-D2 TaxID=1768765 RepID=UPI000829DFE1 +----AARLAALAARVGGRVGVVLRESGGETLL-ALGAQERFPLCSTFKVLAAAAILARVE +RGAERLERALPLGPDDLQSYAPVARAKVEAAMSLEEACAAALVWSDNTAANLLLDALGGP +EALTAFLRAQGDATTRLDRREPELNSALPGDPRDTTTPAAMAATLDRLLLGPALAPASRA +RLEGWMVGCRTGLKRLRAGLPADWVVGDRTGTGDNGTANTVALLRPPGRAPLVAAVYITG +TAGPAEARDAPHAEVGRIVA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas TaxID=40323 RepID=UPI000DA943DB +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTTFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756E205 +---AQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGSYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] BlaMmas n=3 Tax=Mycobacteroides abscessus TaxID=36809 RepID=A0A0S2SQE7_9MYCO +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111E047B +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSNSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. P3 TaxID=2135430 RepID=A0A2R4JLW7_9ACTN +---VTAHLSELEARHGARLGVFAYNMRTRRSV-RHRADELFPVCSLFKTLAVAAVLRDLD +--PAALDRRVHYSADDVVENSEITKGHVADGMTIAELSAAAIWHSDNTAGNLLLRELGGP +AAITRFARSVGDRVTRLDRWEPELNSAEPWRTTDTTSPYAIARTYARLVLGDALRAPDRH +RLTDWMLGTVTSANRFRAGLPPTWTIADKTGGGWYGANNDAGIAWAPDGTPIVLAVQLTK +PDREAPYDHALIVETAGVLA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00046F2AA0 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLSGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Streptosporangium sp. 'caverna' TaxID=2202249 RepID=A0A2Z3V1H8_9ACTN +--EARRRLRALEASFKGRIGAYALDTATGKTV-TYRSGERFPLLSTFKASAAAAVLHKAR +TDPGLMDRVIHWKQSEVKANSPVTEKHVKDGLSVARLCEAAITQSDNTAGNMLLRQIGGP +AGLTRYFRSLKDPVSRLDRWETELNEWTPKAKRDTTTPAAMGQNLRGLATGTVLNAKDRA +RLNGWLRANKTGDERIRAGLPTTWTIGDKTGTTSYGAANDIAVVWPGKGAPLIMTIYTNR +RAAGALNDNKVIADTAAILA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WM6378 TaxID=1415557 RepID=A0A0M8SWQ3_9ACTN +--DVADELSRLERTHHVRIGAYALDTATGRTV-TYRGNEKFPSLSTFKAMVCAAVLDKAR +REPGLMDKVIHWKKSDEVPNSPATAGQGDKGMTVADLCHAAITRSDNTAGNLLLGRIGGP +QGLTHYYRSLGDPVSRLDRWEPDLNVWKPGERRDTTTPAAMGRNLARTSLGSGLAPADRD +RLNGWLRATVTGDERIRAGLPNDWTVGDKTGTSDYGSANDIAVAWPKGGHPVIIAIYTNH +ATADAAADNAVIASTASTLV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007535261 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +AGADASPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 04197 TaxID=2203199 RepID=A0A429DTA7_9PSEU +-----ADFEQLERAFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP +--VAELDRTVTYGQQDLVTNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP +EGLNAVFRGIGDTTSHADRIEPELNDTFPGDLRDTSTPRALAVSLRAFALGDALPEDKRK +ILVDMMRANTTSDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVISVLTDR +AEKDAKIDNKLLADATAAAIK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces parvulus TaxID=146923 RepID=A0A369UXA0_9ACTN +----SRSLAALERTHGARLGVFAWNTVSDRIV-RHRGDELFPACSVSKTPAVAAVLRDLD +RDGEFLRKVIRYGADDVDRYAPVTGENLADGMSVSDLCAVAITHSDNTAMNLILKELGGP +TAVTRFCRSIGDTVTRLDRWEPELNSAEPGRVTDTTSPLAMGKTYARLVLTGTLGTADRD +RLKGWLLANTTGDNRLKAGLPASWTVAEKTGTGDYGTTNDVGVAWTDKGEPVVLAVLSTK +ADAEAAADEPLLAEAARVIAD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3Q8GXR8_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPN------------- +----------------------- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111CFB3E +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKVDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=2 Tax=Aurantimonas manganoxydans TaxID=651183 RepID=Q1YJJ5_AURMS +--RLADTVQGLEERLDARIGIFIRDSGSDWQW-GHREDERFLMASTFKSVLCGAVLEQAE +QGALALDEPVKIRAEDILSYAPVTETRQGSTMTIGELCLATADMSDNTAANLLLDRLGGP +QAVTAFLRGIGDAVTRLDRTEPDLNIFAPGDPRDTTSPKAMATSWETMLVGDGLRPASRQ +QLREWMRHGGVTGKLIRASTPKDWEVVDKSGGGQTHTRNLVAMLTPPGRAPIFVAIYLSD +SPADFSTRNAAVAEIGAAIV--- +>[subseq from] Beta-lactamase n=3 Tax=Stenotrophomonas TaxID=40323 RepID=A0A4Y5QBC7_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAVWVVTAYLQG +ASVDDDQRAAVLARVGTL----- +>[subseq from] class A beta-lactamase n=1 Tax=Carnimonas nigrificans TaxID=64323 RepID=UPI0004B5E2DD +---LSKQAARIEQTLGGRVGAYVMDTESGRTW-HYQADQRFPMASTSKVFMCAALLNNNG +HDGQQLESKAPLSEKQLVAHSPITSRYVGQRLTMAQLCSAALSVSDNTAANLILNQLGGP +QQVTRYARTLGDQVTRLDRFEPQLNEAAPGDARDTTSPRAMALSLQRLLLGDALPKAQRQ +QLLHWMENDQVADELLRAVVPRKWQVADKTGSGLHNTRNIVALLQPPHHKPVIVTIYMTG +VGQQMAQRDEAIRALGKTIV--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=A0A1H2GZY0_9PSEU +-----ADFEQLERTYRARVGVYAVDTATGREV-TFRADERFAYASTHKVFSAGGVLQRTP +--IAELDRTVTYGKQDLVVNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP +EGLNAVFRGIGDTTSHADRIEPELNDTFPGDLRDTSTPRALAVSLRAFALGDALPEDKRK +ILVDMMRANTTGDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVVSVLTDR +PDKDAEIDNKLLADATAAAMK-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A5CB5D +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDSAPIVMAVLTVP +EDPTSTKGKPTIAAAARIVLRAf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC 05977 TaxID=2203208 RepID=A0A429CHM6_9ACTN +-----ADFEQLERTYRARLGVYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLRRTP +--VAELDRTVTYERKDLVVNSPVTEKHVATGMPLRAVMDATLRYSDNTGGNLLFRELGGP +EGLNAVFRGIGDTTSHADRIEPELNDTFPGDARDTSTPRALAVGLRAFALGDALPEDKRK +ILVDMMRASTTGDQNIRAGVP-GWPVADKTGTAAYGTRNDIGVVWPPNRAPIVISVLTDR +SEKDAKIDNKLLADATAAAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=A0A1Q1PJ97_9VIBR +--KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD +NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000F68D0CC +----------------------------GARV-GWISTALRVFESTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. PLAI1-29 TaxID=2053010 RepID=UPI001438B923 +--AARRELRALEREHGARLGAYAHDTATGRTV-AYRADERFPMCSVFKTLGAAAVLRDLD +REGEFLARRIHYTERDVQRHVPVTSRNLAGGMTVEELCACSITHSDSAAANLLLHELGGP +TAITRFVRSLGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGRTYGSLVLGDALDAGDRR +RLTGWLLANTTSEHRFRAGLPGDWTLADKTGGGEYGTNNDAGIAWPPGRPPVVLTVLTTK +PDPDAGADDPLVAKAASVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SAJ15 TaxID=2011095 RepID=UPI0011852A56 +----TDELKALERKYHARLGVYAVDTGTGREV-AYRDGERFAYNSTFKAFVAGAILRKFP +--RGERERVIRYSKDALLPNSPISEKHVATGMTLTALCDAAVRYSDNTAANLLLEELGGP +KALDATLAELGDDVTEMVRDEPELSSWVPGEKRDTSTPRAFTEDLRAFTLGDVLPKAERA +QLTTWLRTNTTGDETIRAGMPKGWVVGDKTGTGYHGARNDMAVVWRPGAAPLVMTVFSYR +DAKKAAPDNKLIAEAAAVVAD-- +>[subseq from] Beta-lactamase n=2 Tax=Uliginosibacterium sp. TH139 TaxID=2067453 RepID=A0A2N4XU20_9RHOO +---FEDILASHEARLGGRIGLAILDTGSGALQ-TVKGTQRFPMMSTFKTLACATLLAEVD +AGRLRLETQVEIRREALLSYSPVTGKFVGQSFSLQQACDATMHTSDNTAANLVLEAIGGP +AAVTRFMRGLGDDVTRLDRIEPELNSALADDPRDTSSPVAMVRSLQALFFGDVLRPASRD +RLLQWMRGNEVAGPLFRATLPPGWAIADRSGAGDNGSRGITAILWPPQRAPLIVSLYLTG +TRADMPELNRSVAEIGREVFAAy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A2Z6A9G9_SHISO +------------------------------------------MMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKLw +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. WM6378 TaxID=1415557 RepID=UPI00099B61EE +--DVADELSRLERTHHVRIGAYALDTATGRTV-TYRGNEKFPSLSTFKAMVCAAVLDKAR +REPGLMDKVIHWKKSDEVPNSPATAGQGDKGMTVADLCHAAITRSDNTAGNLLLGRIGGP +QGLTHYYRSLGDPVSRLDRWEPDLNVWKPGERRDTTTPAAMGRNLARTSLGSGLAPADRD +RLNGWLRATVTGDERIRAGLPNDWTVGDKTGTSDYGSANDIAVAWPKGGHPVIIAIYTNH +ATADAAADNAVIASTASTLV--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium obuense TaxID=1807 RepID=A0A0J6VXK4_9MYCO +-----DRLAALGRRHNARIGVYAVDLGSDRTV-EVGADDTFAMCSTFKAYASAAVLQRAQ +QGRLALTDAVLVGRSDIREHSPVTEPRVGSTMTLAELCQAALQQSDNAAGNLLLRTLGGP +SAITDFARSIGDDRTRLDRWETELNTAIPGDPRDTSTPRALGSGFRAVLTGDVLDGAHRQ +MLEDWMRANQT--SSMRAGLPGGWVTADKTGSGGYGTTNDVGIAYGPQGQRWLLSIMTRS +ATPDADSLRPLIGEIAAAVA--- +>[subseq from] Class A beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A6B1N1E4_9ACTN +------ELADLERRYGARLGVYARNTRTGRVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMDKVIHYPPHDLLPNSPRTQENQATGMAMADVCAAAIQYSDNAAGNLLLRQLDGP +AGLTRFFRSLGDDVSRLDRWEPELNTAIPGDPRDTTSPEALAASIERLALGRALAAADRE +RFVGWLKGNTTSGARFRAGLPEGWTIADKTGTGDYASANDMGVAWTTRRTPVVLAVLSTK +EGKDAPVDEALIAEAARIAAR-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Citrobacter freundii TaxID=546 RepID=E7DK52_CITFR +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPM-------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium alvei TaxID=67081 RepID=UPI00138B42F5 +---VDDRLAELERRDNALIGLYATNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQLAG +RGQLSLDNRVFVDPEAIVPNSPVTETHAGAEMTLAELCRAALQRSDNTAGNLLLKTIGGP +AGITEFARSVGDERTRLDRWEVELNSAIPGDPRDTTTPAALAIGYRAILAGDALSPPQRR +QLEDWMRANKT--SSMRAGLPDGWTTADKTGSGDYGSTNDVGIAYGPHGQRLLLAVMTRS +QADDAEGLRPLIGELTALV---- +>[subseq from] Beta-lactamase/transpeptidase-like n=1 Tax=Desulfoluna butyratoxydans TaxID=231438 RepID=A0A4U8YQ49_9DELT +--SLTKTIADIEQALGSPVGVSIYDAKTKTTW-SHHGDRRFPLMSTFKTLACAKALRDIE +AGALSFDDSVVIEKTSLVTWSPVTSNHVGQAFSLKQACESMMTMSDNTAANIVLTQTGGP +QALTSFARSIGDTVTRLDRMEPDLNEARKGDLRDTTTPDAMAGNLRTLVLGNELSDASKA +LLTNWMRGNKVSGSLLRSVLPKGWDIADRSGAGGHGSRGIAAVVWPAPEEPLVVCIYLTQ +TTASFEELNKSIASIGRAIFALy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-4428 TaxID=1609137 RepID=A0A0F0H8V7_9ACTN +----VRRLRALEREYGARVGAYARDTGTGRTV-RYRADELFPMCSVFKAPAAAAVMRDLD +RDGGFLARRIRYTAQDVAGGGSVTGENIAQGLTVAELCSAAIAQSDNCAANLLLRELGGP +SAITRLCRSVGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIARTYGRLVLGDALVPRHRE +LLTRWLVSNTTSGDRFRAGLPRDWVIGDKTGAGSYGTNNNVGIVWPPGRPPVELAVLTTK +PEAAAPRENALVARAAEVLA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0009B638F5 +--KLNEDISLIEKQTSGRIGVSVWDTQTDEHW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLTGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007552FD7 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFDDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix sp. CB00851 TaxID=1835005 RepID=UPI0009FAA2DA +-----DHLVELERKFDARLGVYAVATGTGTTV-EHRADERFAFCSTFKGLAAAAVLHRHP +--LSHLDTVVTYTEADLMASSAITRQHVATGMTIRQVCDAAVRHSDGTAGNLLLRDLGGP +AGLTAYLRALGDTVTRADRFEPHITTAVPGDPRDTTTPRAIGTDYRRIVLGDVLPPDQRA +FLRDLLERNATGTLRVRAGVPRGWTVADKTGTGDYGTVNDIAVVWPPDTAPLVVSIMSSK +AAADAGYDQALLAEAAAYVV--- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. Leaf183 TaxID=1736291 RepID=A0A0Q5RUM5_9MICO +-----ASFRQLERQHDARLGVVAVDTGSGHRV-AYRSGERFAFASTNKVFIAAAVLAGSS +--DADLDTVVHYDRGDLLSYAPVTSRFVDSGMTVRELVDAALRFSDNTAANLLVERVGGP +DAVERYLRGIGDRTTNVDRLEPELNEATPGDPRDTTTPAQFVTDLRKVLLGTTLDTTDRT +FLRDTMLDNTTGAATVRAGVDPTWPVADKTGTGEYGVRNDIAVVYPAGRAPVVVVVMTSR +DQPDATTDDALVAAATKAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces chartreusis TaxID=1969 RepID=UPI000D38220C +--ATTDRLRLLERQHGARLGVFAYNVRTRRTV-THRADELFPMCSVFKTLASAAVLRDLD +RDGEFLGRRIHYTEADLPKGSDKTREHLAEGMTVAELCEVAITYSDNGAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYGRLVLDDALNRPDRR +LLTHWLLSNTTSGKRFRAGLPKTWTVADKTGSGSYGTTNNVGVAWTPDGTPVVLSVLSTK +PAQDAAWDDALVAETAALL---- +>[subseq from] BlaMab n=5 Tax=Mycobacteroides abscessus TaxID=36809 RepID=A0A0U0X1M3_9MYCO +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] Beta-lactamase (Penicillinase) n=2 Tax=Mycobacteroides abscessus TaxID=36809 RepID=A0A655KS92_9MYCO +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] Beta-lactamase n=3 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A0I9QPS5_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKDWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001120187E +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLSEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=2 Tax=Pannonibacter phragmitetus TaxID=121719 RepID=A0A0U3P9E6_9RHOB +--QLAETVTKTESRLNARVGVVLHDTGSGWSW-ANRADERFLMNSTIKTPICGAILSAAD +AGTLTLDEELPVLQSDIVSYAPVTEKKVGQTMPLSELCLATIDMSDNTAANLLINRLGGT +EAVTEFFRSTGDTVSRLDRLEPDLNTFKSGDPRDTTSPAAMAATLEKLLLDDVLSPQSRN +QLTEWMSHGGVTGALLRKTAPEGWHIADKSGSGDQ-TRNIIAMITPPDRAPWIAVIFVSD +VKADFATRNGALQDISAAVID-- +>[subseq from] Beta-lactamase n=1 Tax=Haloactinopolyspora alba TaxID=648780 RepID=A0A2P8DE99_9ACTN +---TDDAVHRLERAYDTTIGLAAANLATGARL-VHRAGDRFPILSVFKTLAVAAVLRDHD +LHGETLRRRVWFPPADVLEYAPVASEHVDTGMTIEQMCAAVLHLSDNTAGNLLLREVGGP +QGQTAFVRSLGDRTTRLDRWEVALNTAIPGDVRDTTSPAAIARTFARLLTGTALHRHDRA +RLRQWMLENRTGDARLRAGLPDGWRVADRTGTGAYGTANDVGVAWNPAGEPVVIAALTRR +DDQDATADETVLADVAGLVAE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1W5MZF6_9BACT +---ASHPLAQIEARTGGRLGVAVIDTANGRQW-QYRGSERFPMCSTFKLLLAAQMLQRDQ +QGLDSLQQRVTYPRSALVPYSPTTETQADGALTVAELCEATVVLSDNTAANLLLARQGGP +QGLTQWLRDMGTMHTRLDRLEPALNSATPGDERDTTTPLSMARAVVALAKGPHLDAGHQA +QLLQWLKASPTGAKRLRAGMPPGWLVGGKTGTGDNGTANDVVLVWPHHRQPLVVSAYLTQ +TPLAPAARDAALAEVGQAVAHWf +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas humi TaxID=405444 RepID=A0A0R0CGG3_9GAMM +----ARDFTALEAESGGRLGVCLWHPASGARY-GHRMDERFPMCSTFKFLLSAAVLHRAD +HGQLSLDQRVPVRAADIINHSPGTERHVGKDMTVRDLCRTTMVTSDNAAANLLLPLVGEP +AGLTTFLRAQGDAITVTARYEPDANRFAVGDPRDTTSPAAMAGNLQRFVLGDALSPASRQ +QLADWLIDNETGDARLRAGLPQGWRVGDKTGSNGKDATNDIAVLWPEGGTPWLLASYLQG +SPLDDDGRNGILRRVGELA---- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. 6K102 TaxID=2530382 RepID=A0A4R5EYJ1_9ACTN +--RATKELRALETSFKGRIGAYAIDTATGRTI-AYRSGERFPLLSTFKTMACAAVLHKAR +TQPGLMNKRVRWTARDLVDYSPVTEKHVKDGMTVAGLCDAAITMSDNTAGNMILKQIGGP +AGLTRYFRSLKDRVSRLDRWETELNDWTPKSRRDTTTPSAIARDLRAVTYGKALNAKDRA +QLNAWLIANTTGDARIRAGLPKTWTIGDKTGTNSFGGGNDIAVIWPNRAAPIIMAIYTNR +RP-GLAADDKTIAKTAEVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. HDW3 TaxID=2714923 RepID=UPI00140BA9B6 +-tQMAASLKQLEAKAQGRLGVHVVDTGSGQEF-GYRSDELFMMLSSFKLLASALVLARVD +RGEESLERRIPYRKQDLVPWSPVTDAHADGDLTLAQLCHATITTSDNTAANLILASFGGP +EALTTFARQIGDNVTRLDRNEPDLNMRLGTNSLDTTSPRAMAMSMKKVLVGDVLAPSSRK +LLREWLIANTTGGKRLKAGLPVGWTIGDKTGTNKS-DANDIGILFPPQRPPILVTAYLAD +SSASSQIKDETLAEVGMLAT--- +>[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) TaxID=405948 RepID=A4FHM7_SACEN +---HDDHLAGLERKFGARLGVYALATGTGATV-AHRADERFAFCSTFKALATAAVLHRNP +--MSHLDALVTYGEADLMKSSVITRQHVSTGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP +AELTAYARGLGDEVTRMDRVEPLIVEATPGDPRDTSSPRAFGTDFDELVLKDALPEDKRA +FLRDLLQRGTTGARRIKAAVPPGWTVANKTGTGDYGTLNDIAVVWPPDSAPLVIAIMSSK +PAKDAEYDEALLAEAAAHVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000755C5F9 +---AQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGSPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. S816 TaxID=2283197 RepID=A0A4S2IY51_9ACTN +-----GELTDLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP +AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLAVGRALAAPDRE +RFVTWLKGNTTSGARFRAGLPEGWTIADKTGTGDYASANDIGVAWTTRRTPVVLAVLSTK +EGKDAPVDEALIAEAARIAAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces galbus TaxID=33898 RepID=UPI00052E53C2 +---LSRQLGELEREYSARLGVFARDTATGRTV-AYRADERFPLCSVFKTLAAGAVLRDLD +RDGEYLAKRIHYTKEYAEAYSPITGTNVEAGMTVGELCSATVSHSDNGAGNLLLRELGGP +TAITRFCRSLGDRTTRLDRWEPELNTAEPWRTTDTTTPRAIGGTYARLLLGRALRDADRE +LLTDWLIANSTNVQRFRAGLPADWTLADKTGGGAYGVANDVGVVWPPGRPPLVLSVLSTK +YDPAGPTDNPLVARAAGLVA--- +>[subseq from] Uncharacterized protein n=1 Tax=Tatumella sp. OPLPL6 TaxID=1928657 RepID=A0A2G8C4L5_9GAMM +-eEFKKELSNLERSSQGKLGVYLIDPSAKQSF-SYNGDERFPFCSTSKILVTAKLLHDSQ +SLPILLDSKVDIKQTDLVNYNPITSKNVGKSMTVSELSMAALQYSDNTAMNLLLQKAGGI +DAINKFARTLGDKDFLLSRNEPSLNTSIPGDIRDTTTPRSMASTVEKLTLGNGLINEKKK +TLVTWMKGNTTGGASIKAGIPSTWVIADKTGTGDYGTTNDVAVMWTDKNKPLILVTYFTH +FEKDAEPRKDVLSKAAKIVTSY- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI000CD33EC3 +--KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATLLSDMD +DEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075467DC +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S115 TaxID=1394650 RepID=A0A0I9QPS2_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPGLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] carbenicillin-hydrolyzing class A beta-lactamase CARB-23 n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00046D5C8C +--NLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Geodermatophilus normandii TaxID=1137989 RepID=UPI000D71D0E8 +---VAGAFAALEERFDARLGVFAVDTGSGRTL-EHRADERFAYASTIKALAAGALLARTS +--PADLERGVPINAGDLAAYSPVTEGRVGGAMTLAELCDAAVRFSDNTALNLLLRELGGP +AGLDAALEGIGDDVTEVARTEPALNSAVPGDPRDTTTPRALAGSLRF-YAVDGAAEDDRA +LLADWLRRNTTGDALIRAGVPGDWEVGDKTGTGAYGARNDVAVLTPPGRAPLVLAVMSSR +DEPDAEHDDALIAEAARVVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000751B91F +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVVWPPSHAPLVIAASFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Agrobacterium rhizogenes TaxID=359 RepID=UPI0005524533 +----QQRIAALESKHPGRIRVSILDMASGKRI-EHREGERTLICSTFKVLAAALVLTRVD +KGEETLDRRIHYLKSDLVESSPATRSQLGNGMTVAELCAAAMTLSDNTAANLLLASFGGP +KALTAFCRSLGDDITRLDRMEPALNYDTPDDQRDTTTAAAMLENLRRLLFTDLLSAASKS +QLAAWLMINKTGDTRLRAGLPKDWLAGDKTGTNGDGNANDIAVLWPTNRAPIIVTAYCEI +PGIAADERNSIIAEIGRIAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE4EE6 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVVWPPSHAPLVIAASFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A572A0 +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIPYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. WMMA1423 TaxID=2591108 RepID=UPI0011475956 +-----ARFAALERRHGARLGVYALATGTGAEV-AYRADERFAFCSTFKALAAAAVLHGNP +--LGHLDDRVTYTRADVDSISPITRDRVATGMTVRELCDAAIRYSDGTAGNLLMRDAGGP +AGLTAYLRGLGDTVSRMDDYEPELNRVRPGDPRDTTTPRAIAADYRAIVLGDALEPAKRA +LVRGWLERSATGARRVKAGLPRGWKAASKTGTGDYGRANDIAVVWPPRGGPLVVAVMSDR +RGYGAPPKNALIAQAAALVA--- +>[subseq from] Beta-lactamase n=1 Tax=Delftia acidovorans TaxID=80866 RepID=A0A2M9PVE8_DELAC +-qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ +QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEPPLVLSDNTAANLLLDASGGP +QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA +LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE +CPADAPQRDAALASAGKAAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007561031 +--AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMADMLQRLLLGDTLREPQRA +QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAAIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005E27128 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYPRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI000C268544 +-----NELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRSL +SEPGLLDQRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP +EDPTSTKGKPTIAAAARIVLRAf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces atriruber TaxID=545121 RepID=UPI0006E331A2 +--RLASRFTALERKHGGRLGVHALATGTGATL-THRADERFAFCSTFKTLAAAAVLHHRP +--LARLDERVTYTAADVDSISPVTEKRIATGMTLRELCDAAIRYSDGTAGNLLMREIGGP +AELTAYLRRLGDSTSRMDHYEPELNDVRPKDPRDTTTPRAVAADYRALVLGDALPAAKRA +LLEDWLRRNATGERRIRAGLPEGWRVADKTGTGNWGRANDIAVVWPPHADPLVLAVMTDR +PGRDAPPVNAFIAEATELIVA-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. PID23_8 TaxID=1583767 RepID=A0A3A2HWH8_9VIBR +--QLNVNLAAIEQHIAGRIGVSVWDTQTDEQW-DYRGDERFPMMSTFKTLACATMLSDMD +SGKLNKNATAKVEERNIVVWSPVMDRMTGQTTRVEHACEAAMLMSDNTAANIVLRSVGGP +RVVTMFLRSIGDKATRLDRYEPGLNEATPGDKQDTTTPNAMVNTLHTLLEGEALSYESRT +QLKIWMQDNKVSDSLMRSVLPKDWSIADRSGAGGFGSRGITAVIWKENHKPIYISIYLTE +TELSLQARDQAIAKISQLVLEEy +>[subseq from] class A beta-lactamase n=1 Tax=Desulfoluna spongiiphila TaxID=419481 RepID=UPI000B891C45 +---LENRIKEIEHALGARVGVSLYEVETSESW-SYKGDIRFPLMSTFKTLACAKTLLDVE +QKKVSFDDSVVIEKTSLITWSPVTKHHAGQAFSLKQACAAMMIMSDNTAANIVLDKTGGP +TALTAFMRSIGDAVTRLDRMEPELGEALEGDVRDTTTPNAMADSLHVLLFGDVLSKASKT +QLTQWMRSNKISGSLLRSVLPDGWTIADRSGAGGHGSRGITAVVWPETQPPFIVCVYLTQ +TKASFDERNKAIAEIGRELFKLy +>[subseq from] CBP family penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Clostridium sporogenes TaxID=1509 RepID=UPI0005F89AE6 +---YNSAFSKIESDYGVKLGVYAFDTETNKEV-TYNADKRFAYCSTFKSLISGAILQKYS +--SDQLKQVIKYSPKDVLSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP +NGFKSALNQLGDTVTEPARIEPELNVATPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKK +ILINWMSGNATGDKLIRAGAPKDWMVSDKSGTGSYGTRNDIAIVIPSNKKPIFIAILSSK +NDKDAKYDDKTISEASKIVFDYf +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00111F7325 +---AAADFAALEKASGGRLGVTVLDTRSGRRIgGHRQAERFPMCSTFKSMLVAHVLSLAD +AGRVSLDSRVAVAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVTGGP +AALTAFLRDHGDRVTRNDRYEPDMNRFAAGDPRDTTSPAAMAASLALFAVGDGISAASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG +ASVDEEQRAAVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000752AA7E +--AAQAQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAEAMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Leifsonia sp. Root227 TaxID=1736496 RepID=A0A0Q8UQ19_9MICO +--ATTRAFAALERSHAAALGVTAIDTGSGRTV-GFRADERFPFASSNKTFIAAATLQRAT +--TADLDTVIHYTQADLLDYAPITSRFVDTGMTVRELIDAMLRFSDNTAANLLVARLGGP +DAVEQWMRGIGDRVTNVDRVEPDLNAAIPGDPRDTTTAAQFATDLRSVVLGKTLETADRT +LLRNTMLDNTTGDDTIRAGVDPAWPVADKTGTGEYGVRDDIAVVYPAGRAPIVVVVLTRK +DAPDATPDNALLAEATKIAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Mannheimia haemolytica TaxID=75985 RepID=A0A3Q8G682_MANHA +--TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP +--EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV +EQYQRILRQLGDNVTHANRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT +ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ +FTEEAKFNNKLVEDAAKQVFH-- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI0003A4819E +----QPDFAALEKAFDARLGVYAIDTGDGREV-AYHADDRFAYASTHKVFNAAAILHRGD +----DLARTVTIRQSDLVPNSPITEKHTGEQMSLQSVLDAALRYSDNTADNVMFGEIGGP +AGLAAELRRLGDTVTRVDRIEPALNETSPGDVRDTTTPRVWAKDLRAVALDAGLPADKQA +VLTKIMRANTTGAHVIRAGVPADWQVADKTGTADYATRNDIAVLWPPRRAPIVLAVLSDR +PQKDAKTDDKLIAQAAAAVVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075CF7CF +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVAERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_032 TaxID=2175650 RepID=A0A2W1QV61_9MICO +--ATTRALDALERRDDARLGLVAIDTGSGATV-THRAGERFAFASAAKVFIAATVLDDAR +--SGDLDAVVPIEQRDLLSYAPVTSQHVGSGMTVRALLDAMLRSSDNTAANLLVARVGGP +SVVQQWLRGIGDQVTQVVRVEPDLNEATPGDERDTTTPAQFAADLRTVLLGDALRPEDRK +MLVETMAGTTKGAATIRAGVPTGWSVADKTGTGSYGVRNDVGIVTPPGRAPIVLVVMTSR +SRADAKPVDALVAAATKVTV--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI001110F326 +-----ADFAALEKASGGRLGVTVLSTGNGRRIsGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPLARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax carolinensis TaxID=553814 RepID=A0A240TTT7_9BURK +--QWSDTLAGIERAAQGRLGVALLDTGSGLAL-GWRQDERFAVASTFKLVLAGWMLALVD +QGRERLDARVHYAAADVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP +AGFTAFVQSLGDGITRLDRTEPTLNEAAVGDPRDTTTPLAMLQTMQKLVLGDALTTLSRA +WLQRWLVETGTGDQRLRAGVP-GWTVGDKTGTADSGTANDVAVLWPPGGAPVLVTCYLTR +STAQPAQRDAAIAQVARAVAT-- +>[subseq from] Beta-lactamase n=1 Tax=Granulicella sibirica TaxID=2479048 RepID=A0A4Q0SY32_9BACT +----PAAFARLEQTNGGRLGVAVLDTATSERS-GHRAGERFPMCSTFKFLLASAVLQRVD +HHQETLDRLAAVPPKPLLGNSPLTEPHAGATMSIASLCHAALTRSDNTAANILLESIGGP +AGMTAFCRAIGDPVTRLDRTEPTLNESLAGDPRDTTSPVSMVTNLKSILLGNVLAQSSRE +QLTTWMEANLTGLDRLRANLPTAWRAADKTGSNGEHTTNDIAVLWPANRPPVIVAAYITQ +CIGPESKRATMLSEIGRLVR--- +>[subseq from] Beta-lactamase n=1 Tax=Geodermatophilus normandii TaxID=1137989 RepID=A0A317QLD0_9ACTN +------AFAALEERFDARLGVFAVDTGSGRTL-EHRADERFAYASTIKALAAGALLARTS +--PADLERGVPINAGDLAAYSPVTEGRVGGAMTLAELCDAAVRFSDNTALNLLLRELGGP +AGLDAALEGIGDDVTEVARTEPALNSAVPGDPRDTTTPRALAGSLRF-YAVDGAAEDDRA +LLADWLRRNTTGDALIRAGVPGDWEVGDKTGTGAYGARNDVAVLTPPGRAPLVLAVMSSR +DEPDAEHDDALIAEAARVVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis alba TaxID=53437 RepID=UPI0005A63392 +--DVEAEFEALEAEYDTRLGVYALDTGSGEEV-EFREDERFAFASTFKSLLAGVVLSENS +--LEEMERVITYDEDVLVSHSPITEENVGTGMSLLELCDATVRFSDNAAANLLLEELGGP +EGFTESLEETGDDVTTLDRYETDMSAAVPGDERDTSTPEALAGSLEAFTLGDVLPEDRRE +VLVDMLVRNMTGDAVIRAGVPEGWVVGDKTGTGGYGTRNDIAVVWPEEGDPIVLAVLSTM +EVEDAEPQDSLIAEATEVVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus halodenitrificans TaxID=1482 RepID=UPI00136B1F91 +-----------------------IDTGTNQRL-QYNPDDRFAYASTFKVLASAILLKQNS +--IEDLERVVTFSKDDLVTYSPVTEKHVDTGMTLGEISEAAIRYSDNTAANLLLEELGGP +EQFKQALRDLGDHVTQPERFETELNDFTPGKKRDTSTPKAMVNTLKKVALDDFLPDDKRE +LLHNWMKGNATGDKLIRAGAPAEWVVGDKSGAGSYGTRNDIAIVWPPDREPIVIAVMSRH +EEEDAEYDDELIAKAAEIALN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. OK838 TaxID=1882762 RepID=A0A239NLA0_9BACI +--TAMEKFKQLEKEYDARLGVYAIDTGTKETV-EFRENERFAYASTFKALAAAVLLKQNP +--ISVLEEIRTFTNEDIVTYSPITEDFVNKGMSLGKIAEAAMQYSDNTAGNLLFEELGGP +DGFEKALRESGDTITMADRIEPDLNEAIPGESRDTSTPKAIATTLGVFGISEYLPADKQE +IFTNWLKGNTTGDSLIRAGVPESWVVGDKSGAGGYGTRNDIAIVWPPNREPIIIAIMSSR +NEENASFNDKLIAKAAKVIAQAy +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00092C54EE +-----DELASLERDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium goodii TaxID=134601 RepID=A0A2M9FBU0_MYCGD +-------IADLERRHNALIGIFAANLDSNRTV-AHRADEPFAMCSTFKTYLAARVLQKAE +RGELSLDDRVFVDPSVLLVNSPITETHAGGEMTLAELCQAALQRSDNAAANLLLTKIGGP +AEITAFARSIGDQRTRLDRWEIELNSAIPGDPRDTSTPAALGGGYRALLAGDALSTPQRQ +RLDEWMRANQT--SSMRAGLPDGWTSADKTGSGDYGSTNDVGIAYGPQGQRILLAVMTRS +RDDDAPGLRPLIGEVTALV---- +>[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis sp. YBE204 TaxID=1282363 RepID=V4QLD1_9CAUL +---LGKRLMEIQARHGGRIGVSTLDTAADGSL-NLNSTERFAMCSTFKWVLAAAILKAVD +EGKLTVAQEVKYSKADIVDHAPVTTMHLEKGMTIGDLCSATVAVSDNTAANLLLPLIGGP +EGLTAFVRGLGDTVTRLDRTEPELNSNVEGDARDTTTPDAMSGLLRTVFTGKVLTPKSLS +LLTDWMKATTTGPDMIPAGLPQGWTVGHKTGRGANGAVNDVAVIWPTGEVPIFLAIYTTG +GTLDDKARNAIVADVTRLVVD-- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI000D4F99AE +--KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD +DEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium glycinendophyticum TaxID=2589807 RepID=A0A504U5L1_9RHIZ +----SAAARHLERQLGGRLGLMVVDIETDRRW-GYRADERFAMASTFKALACAALLDAG- +--EAVQGRSMTIEAKDLQTYSPVTSKKVGSAMTAAELCAVTLATSDNTAANLVLKALGGP +KRVTAFLRSAGDMVTRLDRREPALNEAKPGDPRDTTTPQAMATTIGDLLLGDTLTADARG +RLTGWMEANAVADGLLRAGVPKDWRIADRTGAGGHGTRGIVAVMWPPGRLPVVAAIYLTE +TEASMATRDAAIAEIGRVIAA-- +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T278_9BACT +------AAQQAETELNARVGLVIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLLAAIYLTQ +TDA-------------------- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium porcinum TaxID=39693 RepID=A0A393XUG1_9MYCO +----DDQIADLERRHNALIGLYASNLDSGRTL-AHRPDEMFAMCSTFKGYAAARVLQMVG +RRQISLDNRVFVDREAIVPNSPITETHVGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGITAFARSIGDERTRLDRWEVELNSALPGDPRDTSAPAALAAGYRQVLAGDALSPPQRR +QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS +QADDADNLRPLIGELTAAV---- +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharothrix carnea TaxID=1280637 RepID=A0A2P8HZK1_9PSEU +-----DHLAGLERKFDARLGVYAVATGTGTTV-EHRADERFAFCSTFKGLAAAAVVARHP +--LSHLDTVVTYTEADLMASSAITRQHVATGMSVRQVCDAAVRHSDGTAGNLLLRDLGGP +AGLTAYLRTLGDTVTRADRFEPHLTTAVPGDPRDTTTPRAIGTDYREILLGDALPPDRRA +FLRDLLERNATGTLRVRAGVPRGWTVADKTGTGDYGTVNDIAVVWPPDAAPLVVSIMSGK +ATADAEYDQALLAEAAAYVVD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A346CG34_KLEPN +-------IKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGTGQRGARGIVAL----------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758E7E9 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +AGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. CV4 TaxID=2478711 RepID=A0A3L7B4G1_9ACTN +------HLVSLERKFDARLGVYALATGTGATI-AHRADERFPFCSTFKGLAAAAVLHRRS +--LSDLNSVVRYTADDLMDSSVITRRHVATGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP +GELTAYVRGLGDTVTRMDRIEPAVASGTPGDPRDTTTPRALSTDYHRIVLGEALPPDRRA +FLRDLLERNATGAQRIRAGVPRGWTVADKTGTGGYGTVNDIAVVWPPTSAPLVIGIMSAK +AEKDADYDQALVAEAAAYVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Acidisphaera sp. L21 TaxID=1641851 RepID=UPI00131D34E4 +-----QVFAAIEARRGGRLGVAVLDTATGRTA-GYRQDERFPMCSTAKLPTAGAVLAHVG +--VAGLQRRIHFPKHDLVVHSPLTAPHADTDMTLDAICAAALSQSDNTAGNLMLHIIGGP +AGLTRYLRTLGDEMTRLDRWETALNEAKPGDVRDTTTPAAMLADIQALTLGHALPAPAKA +SLLGWLRGNQVGDARLRARLPPGWQVADKTGTGDFRTSNDAGLLFPPNGPPIIVAAYLTE +GSADDAVREAALADVGAAVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp8998 TaxID=2184557 RepID=A0A3N8GWN5_9BURK +--AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDESLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTAFRLDRWEPELNQAAPGDERDTSTPVAMADMVQRLLLGDTLREPQRA +QLTEWMTGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPARAPIVLAVSFTQ +PRADAAAREDVVASAARIATSAf +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. Leaf261 TaxID=1736311 RepID=A0A0Q4UYV1_9MICO +--ATTRAFAALEQQYGAQVGVRVLDTGSGNTL-GYRDDTRFAFASTSKLLTAGLLLRTAS +--DAELDTVVHYDAADLLSYAPVTSQHVATGMSLRDLVTAALQVSDNTAANLVTEHLGGP +AAVQSALRTLGDSTTNVDRTEPDLNTATPGDVRDTTTPHALATDLRRFAVGDLLTPARRT +LLVSLLEGNTTGGPYVRAGVPAGWTVGDKTGNGSYGTRNDIAVVTPPGRAPIIVVILTNR +GSQDASSDDALIADVTRQVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium neworleansense TaxID=146018 RepID=A0A0H5RLE5_9MYCO +---IDDQIAELERRHNALIGLYAVNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMVG +RRQISLENRVFVEPAAIVPNSPVTETHAGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGITAFARSIGDDRTRLDRWEVELNSAIPGDPRDTSTPAALAGGYRAVLAGDALSPPQRR +QLEDWMRANQT--SSMRAGLPDGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAMMTRS +QADDADNLRPLIGELTAL----- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. A0592 TaxID=2563099 RepID=A0A4V3TAV3_9ACTN +----VRQLRALEREYGAWVGAYARDTGTGRTV-LYRADELFPMCSVFKTPAAAAVMRDLD +RDGEFLARRIHYTQEDVTSGGSVTGANVAGGLTVAELCSAAIAQSDNCAANLLLRELGGP +TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALAPRHRE +LLTRWLVSNTTSGDRFRAGLPRDWVVGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK +ADPAAPREDALVARAAGVLA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=C8CE53_ECOLX +---------------------------------SFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEVDKVAGPLLRSALPAGWFIADKSGAGERGSSGIIAALGPDGKPSRIVIIYTTG +SQATMDERNRQI----------- +>[subseq from] carbenicillin-hydrolyzing class A beta-lactamase CARB-45 n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI000541AE92 +--KLNADISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPGLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. YAU14A_MKIMI4_1 TaxID=2072408 RepID=UPI000D542A00 +------DFAALEKASGGRLGVTVLDTGSGRRLgGHRQDERFPMCSTFKSMLVAHILSLAD +AGRLSLDTRVPITERDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP +AALTAFLRAQGDTVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGDGLPPPSRL +QFADWLVDNQTGDACLRAGLGPRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG +ASVDEAQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. NB1 TaxID=1943571 RepID=A0A4D4JNK7_9BURK +--AWNDALATIERTAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD +QGKERLDHRLHYGRDAVIAHSPVSGPRAGDGLTVAELCAATVSLSDNTAANVLLAQHGGP +ASYTAFVRSLGDAATRLDRYEPHMAEAAAGDLRDTTTPQAMLQTLQKLVLGDVLTPVSRA +LLQRWLLETSTGDNRLRAGAP-GWKVGDKTGTGASGTANDIGVLWPAGGAPVLVTCYLTR +SAASPQQRDAAIAQVARAVVA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura chibensis TaxID=392828 RepID=A0A5D0NQ72_9ACTN +--KVAARLRALEKARGVRVGAYAVDTGTGRSV-SYRGGERFPFASSFKAMACGAVLRKAD +SDPALMDRVIRYEKSDLADFSPVTEKHVGTGMTVADLCHATITRSDNTAGNLVLKLIGGP +PGLTAFLRSLGDASSRSDRAEPGLNHWRPGEPRDTTTPAAWAGDLRALAVGDALAPPDRT +RLVGWLKATVTGGERIRAGLPKTWTVGDKTGTAGYGNAVDVAVAWPPGAAPLVMAVLTTR +PRADAEADEKAVAETARILAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. AA0539 TaxID=1210045 RepID=UPI0004753980 +-----GEFARLEDAYDARLGVYALDTGSGEEI-GYREDERFAYASTFKALLCGAVLEEYG +--LAGMDEVIPYGEEDLLPNSPITEERLAEGMSKSDLCDATVRYSDNAAANLLWDTIGGP +AGLQERLAGLGDDVTRMERWETELNEAVPGDERDTTTPEAFAGNLAGYVLGEVLPEPERA +QLTEWLVTNTTGDELIRAGVGEGWTVGDKTGGGGHGTRNDIAVLWPDSGPPLVLAVFSTR +EEPDADWDNALIAEAASVAV--- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC310 TaxID=1848322 RepID=A0A4R4UH42_9ACTN +---AVKELRALETSFKGRIGAYAIDTATGRTI-AYRSGERFPLLSTFKAMACAAVLHKAR +TRPGLLKKRVRWTARELVDYSPVTEKHVKDGMTVAGLCHAAITMSDNTAGNMVLKQIGGP +AGLTRYFRSLDDRVSRLDRWETELNDWTPKSRRDTTTPSAIARDLRAVTYGKALNAKDRA +QLNAWLIANKTGDARIRAGLPKTWTIGDKTGTNSFGGGNDIAVIWPGKGAPIIMAVYTNR +TP-GLAADDKTIAKTATILA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00084B52F8 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACASMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111D57C3 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACAAMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKSVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B7946 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A127DCD0_9BACI +--TVMEKFKQLEKEYDARLGVYAIDTGTKETV-EFRENERFAYASTFKALAAAVLLKQNP +--ISVLEEIRTFTNEDIITYSPITEDFVNKGMSLGKIAEAAMQYSDNTAGNLLFEELGGP +DGFEKALRESGDTITMADRIEPDLNEAIPGESRDTSTPKALATTLEVFGISEYLPADKQE +IFTNWLKGNTTGDSLIRAGVPESWEVGDKSGAGGYGTRNDIAIVWPPNREPIIIAIMSSR +NEENASFNDKLIAKAAKVIAQAy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075FEA09 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. LHW50302 TaxID=2250578 RepID=A0A367EK46_9ACTN +--RVTEALATLEKRHDRRLGLYMRDTGSGRTV-EYHADERFGFCSTAKVLQAAALLEHAD +--EAQLNRVITYERDDLEDHAPITRKHLDTGASVRALMKAALQYSDNTAANLLFEQLGGP +AGLQRKMRGLGDRTSVFDRTEPDLNDTPPGTTHDTSTPRALAQDLRRFLLDDALAPDRRE +LLASWMRGNTTGDDLIRAGVPSGWKVADKTGSGTYGTQNDIAVAWRPHGAPVIIALMSRG +HDKDSASDKALMAEATKAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia arthritidis TaxID=228602 RepID=UPI0007A3E9D8 +------RLIELERKYDARLGVYARATGTGVTV-AHRADERFAFCSTFKGLAAAAVLHRNP +--LSHLDTVVTYTRDDLLKNASVTPRYVDTGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP +AELTAYARSLGDPVTRMDRIEPAITEATPGDPRDTTSPRAFGEVYHRIVLGDALPADKRD +FLRDLLERNATGAQRIRAGTPQGWRVADKTGTGDYGTLNDIAVVWPPDAAPLVVAIMSSK +ATRDAAYDQVLLAEAAAYVMD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. KS_5 TaxID=1881018 RepID=UPI000898A520 +--ATTDRLRELERQHGSRLGVFAYNVRTRKTV-THRPDELFPMCSVFKTLASAAVLRDLD +RDGEFLRRRIHYTEADLPEGSDKTREHLAEGMTVAELCEVAITYSDNGAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYGRLVLDDALNRPDRR +LLTHWLLSNTTSGKRFRAGLPKTWTVADKTGSGSYGTTNNVGVAWTPDGTPVVLSVLSTK +PAQDAAWDDALVAETAALL---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces yerevanensis TaxID=66378 RepID=UPI0005255915 +--DISRALNDLEREHSARLGVFGRNTVTGRSV-LYRADESFPMCSVFKTLAAAAVLRDLD +RHGEFLALRIRYTEQDVEEGAPVTEENLANGMTVAELCEAAVAYSDNCAANLLLRELGGP +TAITRFCRSIGDRTTRLDRWEPELNSAEPGRVTDTSSPAAIGWTYAKLALGDALTPRDRR +QLTAWLLANTTSTNRFRAGLPEDWALGDKTGTGKYGTTNDAGIAWTPDGTPIVLAVLSTK +PDPDTPMDEPLVAKTAALLAK-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00084A32E4 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVIWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Roseicyclus mahoneyensis TaxID=164332 RepID=A0A316GFJ9_9RHOB +-qTLAATIDRIEQDLDARVGLLIRDSGSDWSA-TYRADERFLMTSTFKTMLCGAVLHRVD +AGDIDLEERIAIETADILDYAPVTETMVGNTMSVGALCHAALDMSDNTATNLLIDRIGGT +QSVTAFLREIGDPVSRLDRREPEVNTFAPDDPRDTTTPAAMASTMEVLLAGDALSPQSRA +QLVDWMSAGGVTGALIRASTPEGWHVADRSGSGNF-NRNIVAMVTPPDRAPYFIAIFLSD +AQADFDTRNAAVIALSDAVMQ-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S105 TaxID=1394641 RepID=A0A0I9QQ02_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDME +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Pannonibacter phragmitetus TaxID=121719 RepID=UPI000F01A607 +--QLAETVAKTESRLNARVGVVLYDTGSGWSW-ANRADERFLMNSTIKTPICGAILSAAD +AGTLTLDEELPVLQSDIVSYAPVTEKKVGQTMPLSELCLATIDMSDNTAANLLINRLGGT +AAVTEFFRQTGDTVSRLDRLEPDLNTFKSGDPRDTTSPAAMSATLEKLLLGDVLSPQSRN +QLTGWMSHGGVTGALLRKTAPEGWHIADKSGSGDQ-TRNIIAMITPPDRAPWIAVIFVSD +VKADFATRNGALQDISAAVID-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. C1-1 TaxID=2491024 RepID=A0A3N9Q430_9BACI +-----AVFSVLEDHYDARLGVYALDTGNGQTI-AYNEDERFAYASTHKALAVGVLLQQLS +--LDELDTQILFSEADLVTYSPITEQHVETGMSLHEISDASIRYSDNTAANLIFNEIGGP +SGFKEALREIGDEVTEPERMETELNDVKPGETRDTSTAKALAESLYAFSLGDALDEEKQT +LLNDWLIHNTTGDALIRSGVPEGWLVGDKTGSASYGTRNDIGIIWPPDEDPIVIAVLSSK +EQADAESDDALIADATEAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Comamonas terrigena TaxID=32013 RepID=UPI000E189C7F +---ASHPLAQIEARTGGRLGVAVIDTANGRQW-QYRGSERFPMCSTFKLLLAAQMLQRDQ +QGLDSLQQRVTYPRSALVPYSPTTEAQAGGALTVAELCEAAVVLSDNTAANLLLARQGGP +QGLTQWLRDMGSMHTRLDRLEPALNSAVPGDERDTTTPLSMARAVVALAKGPHLDAGHQA +QLLQWLKASPTGAKRLRAGMPPGWLVGGKTGTGDNGTANDVVLVWPHHRQPLVVSAYLTQ +TPLAPAARDAALAEVGQAVAHWf +>[subseq from] Beta-lactamase n=1 Tax=Goodfellowiella sp. AN110305 TaxID=1892852 RepID=A0A5B2XUE2_9PSEU +-qAAEAAFAALEAKFGGRLGVSAVDTGTGRTV-GHRADERFLMCSTHKVFVVAAILALRG +RQPGLLDRLIRYDRSQLLSYAPVTSQHVADGMTVSALCEAAITVSDNTAVNLLQQVLGGP +AAATAYVRTTGDQVTRLDRLEPDLNVGAPGDERDTTTPAQFAADLRTLALGDTLDPAGRD +LLTGWLTAATTGGALVRAGLPAGWRAGDKSGSGAAGEVNDVAVVWPPNHAPLVVTVFTAP +TDRASKAGQATVAGAASIAVK-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. ZAC14A_NAIMI4_1 TaxID=2072412 RepID=UPI000D53F5CC +-----ADFGALEKASGGRLGVTVLDTGSGRRIaGHRQDERFPMCSTFKSMLVAHVLHLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP +PALTAFLRAQGDAVTRNDRYEPEMNRFAKGDPRDTTSPAAMAASLARFAVGNGLSAASRL +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGEDTRNDIAVLWPRGGAPWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus shacheensis TaxID=1649580 RepID=UPI00073FFC58 +--DTNNVFSQLEEEYDANLGIYALNTGTNQII-SYREDERFAYASTHKALAAGVLLQQND +--VDELDQTIGITKDDLVNYNPITENYVGEEMTLKELSEASMRYSDNTAGNLILEQIGGP +EGFKEALRDMGDGVTHPKRIEPELNEFIPDETHDTSTPEALAHSLQKFTIGDALPQEKQE +LLTDWLKQNTTGDPLIRAGVPEDWEVGDRTGAASYGTRNAIAIIWPPNEDPIFLSVLSNK +DQEDADYNDELIARATEEVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Ideonella sp. B508-1 TaxID=137716 RepID=UPI00034541B0 +--ALQQALRDIEARAKGRLGLAVLDTGSGRRW-LHRADERFLLCSTFKLLLCAQVLERAA +RGEERLDRPLSFGRGDLVEWSPVTKKAVGRGLSVAQLCEATMTTSDNTAALLLLKTQGGP +AGLTRWLRAHGDTQTRLDRSEPDLNLADPTGEWDTTTPATMADTVQRLCLGAGLPKTVQA +QLQAWMKASTTGAQRLRAGLPTGWQIGDKTGTGD-GISNDVAIVWPPGQAPWVVVAFLSD +CRSPRDVQQACLADLGRL----- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis thermoflava TaxID=84480 RepID=UPI00056D115B +-----VDFADLEARFDARLGVYAIDTGTGREI-AHRADERFNYASAIKSLLAGAVLRRNV +----DLDKVVTYTDADIQPNSPVTKDR--RSVTVREAAEAALLQSDNTAANLLFAEVGGP +AGLAAVLREIGDTTTHPDRLEVELNSAIPGDVRDTSTPRAMAGSLRAFLLGDALPADKRD +LLVGIMRRNKTGTELIRGGVPSEWPVADKTGTGDYGTRNDIGVIWPPGRAPIVLALMSSR +TTADASYDNKLLAEATSRVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinopolyspora mortivallis TaxID=33906 RepID=UPI0003A0D2F8 +-nTVRAEFTRLEQRFGARLGVHALDTGSGEVV-THRADERWAFCSTMKTFTAAAVLRRNT +--VEDLDRRITYTRAELVPYSPVTEKHVDSGMTLRETLRAALRVSDNTAQNLLLRELGGP +EGLRRELRELGDTTSHVDRYEPELNETAPGDVRDTSTPRALAANLREVVLGDALAPEKRK +ILRGAMRNPPLTEELVQAGTPEGWEIEDKSGAGNHATRNDIAVLYPPQRAPIVLVVMTSK +SERDAEYDNALVAEATRTT---- +>[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. NB1 TaxID=1943571 RepID=UPI0010F8689B +--AWNDALATIERTAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD +QGKERLDHRLHYGRDAVIAHSPVSGPRAGDGLTVAELCAATVSLSDNTAANVLLAQHGGP +ASYTAFVRSLGDAATRLDRYEPHMAEAAAGDLRDTTTPQAMLQTLQKLVLGDVLTPVSRA +LLQRWLLETSTGDNRLRAGAP-GWKVGDKTGTGASGTANDIGVLWPAGGAPVLVTCYLTR +SAASPQQRDAAIAQVARAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium smegmatis TaxID=1772 RepID=UPI001303A696 +---VDDRIADLERRNNASIGIYAVDLDSNRTV-AHRADDSFAMCSTFKAYLAGRVLQGGE +RGELSLDDRVFVDPAALLPNSPITEEHAGGEMTLAELCQAALQRSDNAAANLLLKKIGGP +AEITAFARSIGDPRTRLDRWETELNSAVPGDPRDTSTPAALAGGFRAVLTGDVLAPPQRQ +LLDEWMRANET--SSLRAGLPDGWTSADKTGSGDYGSTNDVGIAYGPQGQRILLALMVRT +RGPNADGFRPLIGELTALV---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseofuscus TaxID=146922 RepID=UPI000F6459DD +-----GELADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP +AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALATPDRE +RFVTWLKGNTTSGARFRAGLPGGWTIADKTGTGDYASANDIGVAWTARRTPVVLAVLSTK +EGKDAPVDEALIAEAARIAAR-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces vietnamensis TaxID=362257 RepID=A0A0B5HYG9_9ACTN +-----ARLRRLEREHTARLGVFARDMRTGRTV-AYRADERFPMASLFKTLAAAAVLRDLD +HDGEFLARRIHYTQAYVERVSPVAEKNVAGGMTVAELCDATIRFSDNTAGNLLLKELGGP +TAVTRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLSYARLVLGDALEPHDRA +RLTDWLLRNTTSTEKFRRGLPPEWLLADKTGSPRHGGANDAGIAWRPDGTPIVLSVLTTK +AEEDAPTDNPLVAATAALLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID685 TaxID=2690322 RepID=UPI001370A5B5 +-----GELADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP +AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALATPDRE +RFVTWLKGNTTSGARFRAGLPGGWTIADKTGTGDYASANDIGVAWTARRTPVVLAVLSTK +EGKDAPVDEALIAEAARIAAR-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. cf124 TaxID=1761903 RepID=A0A1I4UC19_9ACTN +---LSRQLGELEREYSARLGVYAHDPATGRTV-AHRADERFPICSVFKTLAAGAVLRDLD +RDGEYLAKRIHYTKEYVDAYNPITGTNVEAGMTVGELCSATVSHSDNGAGNLLLRELGGP +SAITRFCRSLGDRTTRLDRWEPQLNTAEPWRTTDTTTPRAIGRTYARLLLGRALRDADRE +LLTDWLIANSTNVQRFRAGLPADWTLADKTGGGTYGVANDVGVVWPPGRPPLVLSVLSTK +HDPAGPTDNPLVARAAGLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Herbidospora galbida TaxID=2575442 RepID=A0A4U3MBS3_9ACTN +----VAELRALETAYKGRIGVYAYDTATGNLI-TYRSGERFPFASTFKAVLAAAVLDKEP +---DILRKRIRYDQKDLQPHSPVTAKHVATGMTVAQLCEAAVTESDGTAANLLLRQIGGP +KGLTRYFRGLHDPVSRLDRPEPGLNDWSPTDPRDSTTPAAMGRDLHALTLGGALDAGDRE +RLTGWLVGNRTGDRRIRAGLPASWKVGDKTGTATYGATNDVAVVWPAKGKPIIMAIYARR +AGKNAAHDENVIAKTATIVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9012 TaxID=2184562 RepID=A0A3N8E0F0_9BURK +--AAQAELAALEKASNGRLGVAALDTSSGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTAFRLDRWEPELNQAAPRDERDTSTPVEMVDTLQRLLLGDTLREPQRA +QLTEWMSGGARGATGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIAT--- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 2323.1 TaxID=1938841 RepID=A0A286HQ80_9ACTN +-dELSRRLTDLEQQHSARLGVFAHNPATGRSV-LHRADERFPMCSLFKTLAAAAVLRDLD +HHGEFLAKRIRYTAKDVRKYAPVTGTNLARGMTVADLCAAAISYSDNAAGNLLLRELGGP +TTITRFCRSTGDRTTRLDRCEPELNSAEPSRITDTTSPRAIGQTYARLTLGTALTPKDRK +QLTSWLRATTTSGEKFRAGLPSDWAVADKTAGGKYGTNHDVGLAWPPGRSPIVMAVLTTK +REPDAAADNPLVAKTAALLAK-- +>[subseq from] Beta-lactamase n=1 Tax=Desulfoluna spongiiphila TaxID=419481 RepID=A0A1G5H0N4_9DELT +---LENRIKEIEHALGARVGVSLYEVETSESW-SYKGDIRFPLMSTFKTLACAKTLLDVE +QKKVSFDDSVVIEKTSLITWSPVTKHHAGQAFSLKQACAAMMIMSDNTAANIVLDKTGGP +TALTAFMRSIGDAVTRLDRMEPELGEALEGDVRDTTTPNAMADSLHVLLFGDVLSKASKT +QLTQWMRSNKISGSLLRSVLPDGWTIADRSGAGGHGSRGITAVVWPETQPPFIVCVYLTQ +TKASFDERNKAIAEIGRELFKLy +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. 92mfcol6.1 TaxID=1761901 RepID=A0A1W1H3F0_9GAMM +---AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDPALLDRRLPVRTQDLLEHAPVARRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA +GTISFEQRAAVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Virgibacillus pantothenticus TaxID=1473 RepID=A0A0L0QTZ0_VIRPA +-----EAFRLLEKEYDAKLGIYAMDTGTGKTV-SYRAENRFAYASTHKVLAVGVLLQKMN +--VNQLEETVLIKEDDLVNYNPITEKHVNKLMTWKELSDASMRYSDNTAANYILKRIGRP +AGFKQALRDIGDDVTKPERIEPELNKVKPGETRDTSTPKALATSLQTFTMGDVLTKQKQD +LLVNWLKRNTTGDNLIRAGVPEGWEVGDKSGAASYGTRNDIAIIWPPNEDPIILAVLSSR +DEEDAEGNDELIAKATEEVM--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 2323.1 TaxID=1938841 RepID=UPI000BB7C942 +-dELSRRLTDLEQQHSARLGVFAHNPATGRSV-LHRADERFPMCSLFKTLAAAAVLRDLD +HHGEFLAKRIRYTAKDVRKYAPVTGTNLARGMTVADLCAAAISYSDNAAGNLLLRELGGP +TTITRFCRSTGDRTTRLDRCEPELNSAEPSRITDTTSPRAIGQTYARLTLGTALTPKDRK +QLTSWLRATTTSGEKFRAGLPSDWAVADKTAGGKYGTNHDVGLAWPPGRSPIVMAVLTTK +REPDAAADNPLVAKTAALLAK-- +>[subseq from] Beta-lactamase n=2 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A0I9QQ15_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLRSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SUT7_9BACT +--NTERKLAELERKYDARIGVYAIDTGTNYTV-KYRPNERFAYASTYKAFAAAILLQKKS +--VEKMNEVIKYTEEDLVSYSPITEKYVNTGMTLFDLSEAAVRYSDNTAGNLILEALGGP +SGYERSLRKIGDTVTEVNRYEPDLNDFTPGDSRDTSTPKALATNLKKLALNRFLSDDKQT +IFFDWIKGNATGDALIRAGAPKDFVVGDKSGAASYGTRNDVAVVWRPNKEPIVIAIMSRY +NSEDAKYDDKLIEEAANITLKSf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. BK141 TaxID=2512171 RepID=A0A4R7GRC0_9ACTN +-vDLGAEFGDLERRYGARLGVHARNLRTGRTV-AYRAGEPFAMCSTFKAFAAAAVLRDHG +-DCASLDKLIHYPPRDILDNSRQSEAHLATGMTVGQACAAAIQYSDNTAGNLLLRQIGGP +QGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTSTPEALGRTFERLTLGRALARTDRE +QLVTWLKGNTTSVERFGAGLPRNWVLADKTGTGSYASANDVGVAWTTRQTPLLLTVLSTK +NAKDAPVDNRLIRDAAAILA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001123CF2A +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGNERFPLMSTFKTLACATMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI0002EB2DE2 +--KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD +NEKLDKNATAKVEERNMVVWSPVMDRMAGRTTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. CB00013 TaxID=1703945 RepID=UPI00093A2D06 +---ASADFEQLERTFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP +--VAELDRTVTYGQQDLVTNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP +EGLNAVFRGIGDTTSHADRIEPALNDTAPGDSRDTSTPRALAVGLRAFALGDALPEDKRK +ILVDMMRANTTGDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVVSVLTDR +AEKDAKIDNKLLADATAAAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix carnea TaxID=1280637 RepID=UPI000D0DF184 +-----DHLAGLERKFDARLGVYAVATGTGTTV-EHRADERFAFCSTFKGLAAAAVVARHP +--LSHLDTVVTYTEADLMASSAITRQHVATGMSVRQVCDAAVRHSDGTAGNLLLRDLGGP +AGLTAYLRTLGDTVTRADRFEPHLTTAVPGDPRDTTTPRAIGTDYREILLGDALPPDRRA +FLRDLLERNATGTLRVRAGVPRGWTVADKTGTGDYGTVNDIAVVWPPDAAPLVVSIMSGK +ATADAEYDQALLAEAAAYVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium neworleansense TaxID=146018 RepID=UPI000B8A499E +---IDDQIAELERRHNALIGLYAVNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMVG +RRQISLENRVFVEPAAIVPNSPVTETHAGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGITAFARSIGDDRTRLDRWEVELNSAIPGDPRDTSTPAALAGGYRAVLAGDALSPPQRR +QLEDWMRANQT--SSMRAGLPDGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAMMTRS +QADDADNLRPLIGELTAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D71FA +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDMLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DE2C53 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLFDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0003572F2F +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAP--------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007534D23 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVHGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGSPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2T1I906_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SVLTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1D8MAK3_ECOLX +---------------GARVGKIELDLNGGQILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRLLYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPYDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLRDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGADGKPSRIVLIYTTG +SQAT------------------- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium obuense TaxID=1807 RepID=A0A4R5X7C3_9MYCO +-----DRLAALGRRHNARIGVYAVDLGSDRTV-EVGADDTFAMCSTFKAYASAAVLQRAQ +QGRLALTDAVLVGRSDIREHSPVTEPRVGSTMTLAELCQAALQQSDNAAGNLLLRTLGGP +SAITDFARSIGDDRTRLDRWETELNTAIPGDPRDTSTPRALGSGFRAVLTGDVLDGAHRQ +MLEDWMRANQT--SSMRAGLPGGWATADKTGSGGYGTTNDVGIAYGPQGQRWLLSIMTRS +ATPDADSLRPLIGEIAAAVA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111EBBAE +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDEPNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces vietnamensis TaxID=362257 RepID=UPI000698422C +-----ARLRRLEREHTARLGVFARDMRTGRTV-AYRADERFPMASLFKTLAAAAVLRDLD +HDGEFLARRIHYTQAYVERVSPVAEKNVAGGMTVAELCDATIRFSDNTAGNLLLKELGGP +TAVTRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLSYARLVLGDALEPHDRA +RLTDWLLRNTTSTEKFRRGLPPEWLLADKTGSPRHGGANDAGIAWRPDGTPIVLSVLTTK +AEEDAPTDNPLVAATAALLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2R3Q4E7_STEMA +-----ADFAALEKASGGRLGVTVLDTGNGRRIgGHRQDERFPMCSTFKSMLVANVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGALTISDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMAASLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI000813B9F3 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVGSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QC07_STEMA +-----ADFAALEKASGGRLGVTVLDTGNGRRIgGHRQDERFPMCSTFKSMLVANVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGALTISDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMAASLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] serine hydrolase n=1 Tax=Georgenia satyanarayanai TaxID=860221 RepID=UPI0012640C51 +-----------AAESGVTLSVAVTDLAGGATV-TAGEDEQVKAASIIKLPLLAALMADVD +AGELDLDQAVTIPAGDIVGGSGTLKDQFPLDITVAELMELMVQVSDNTATNVLIDLAGGF +GAVNDYVAALGFEDLYLGRKMI--HPASPPLQENYISAEEVTELVTMLWEGEVLSAESSE +HIIDLMRGQLV-DTKFGAVIP-RVHLANKTGELAD-VSHDSGIVLLPGRE-LAITTTTSF +TDLPREEADVFVQETARVVYD-- +>[subseq from] serine hydrolase n=1 Tax=Georgenia satyanarayanai TaxID=860221 RepID=UPI0012640C51 +-------------AQDVRVSVGFSDLGDGDRV-LLGSQEPYNPASVIKLSLLAAVMRQTE +RDLLHLDAPVTISPYMVVGGSGSFQDEMPFTTTVRELVRRMVVESDNTATNVLLYHI-GL +PTTQGLIDDLGLDVMRFNRQMFPG--ELIDEPANVLDVGDTLALLEAMYGDELLGEDSRE +QILTWMGDQEV-DTKFGAVLN-DAPVAHKTGETGN-VTHDVGYFLVPGHES-AVVVLTEV +TSETQEIGNPIVQEIGLAVYNY- +>[subseq from] class A beta-lactamase n=1 Tax=Cryocola sp. 340MFSha3.1 TaxID=1169145 RepID=UPI000362297C +--AAARALAELESQYGATIGVYAVDTGTGRSV-GYRQDDRFAYASTSKVLLAGAVLARSS +--DEQLDATVPYTSDDLVSYSPVTETMAGAGMPLRDVIAAALQKSDNTAANLLFRQLGGP +AELEKSLRALGDETTEVERTEPDLNEAAPGDPRDTSTPRALAADLRAYALGEELPANRRK +LLVDDMTGNATGDPLIRAGVPTGWTVSDKSGAASYGTRNDIAMLTAPGHAPVVMVVLSRK +AEKDAAYDNALVADTAKVL---- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium peregrinum TaxID=43304 RepID=A0A1A0VYD7_MYCPR +---VDDQIAELEHRDNALIGLSATNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMVG +RGQISLDNRVFVDPEALVPNSPVTETHAGSEMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAIGYREILVGDALSPPQRR +QLQDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPNGQRLLLAVMTRS +QADDPKADNPLIGELT------- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter glycinis TaxID=582702 RepID=A0A5B9E1C6_9GAMM +--AIAGELATLERQHGGRLGVAMLDIGSGRHA-GHRAGERFLLCSTGKLLVVGAVLARVD +RGEEQLSRRIVFGPDVILEWAPVTRKHVGAPMTVAELCHAALTISDNTAMNLLLKSVGGP +AAATRFVRSLDDDITRLDRHEPELN--VPDKGLDTTTPDAMLASMRKLLLGNVLSASSRA +QLIDWLRHNTTGETQLRAGMPASWQVGDKTGSGHT-QTNDVAIAWPPGRQPLLVTAYYEG +PADQGDMRKAVLAHVGKLAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00092B4FB1 +-----NELTSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRRQ +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSGGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP +EDPTSAKGKPTIAAAARIALRAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075CF59B +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0006EBF9DF +-------FSVLEDHYDARLGVYALDTGNGQTI-AYNEDERFAYASTHKALAVGVLLQQLS +--LDELDTQILFSEADLVTYSPITEQHVETGMSLHEISDASIRYSDNTAANLIFNEIGGP +SGFKEALREIGDEVTEPERMETELNDVKPGETRDTSTAKALAESLYAFSLGDALDEEKQT +LLNDWLIHNTTGDALIRSGVPEGWLVGDKTGSASYGTRNDIGIIWPPDEDPIVIAVLSSK +EQADAESDDALIADATEAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007599166 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. S23321 TaxID=335659 RepID=UPI0002562616 +------ELESYERDSGGRIGLYAENLATGAKL-SWRADERFVMCSTFKASLAACVLTRVD +RGEEQLAAMIPYGKADLLDYAPVAKQNLATGMSVAEMCKAIVELSDNTCANLLLTRIGGP +AALTTFWRSLGDATSRLDHNEPELNRSPPGNPHDTTTAAAMAGNLRRLVTGEALSPASRA +QLTEWMVGCKTGANRLRGGLPANWTIGDKTGNNGKDASGDIAVAWPKTGAPVLIAAYTQG +GTPTAAQIEAVFARIGRMVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Lentzea aerocolonigenes TaxID=68170 RepID=A0A0F0GVX0_LENAE +---ITGKLRELEKQHTARLGVFATDTGTGRTV-LHRADELFPMCSTFKTIAAAAVLRRDH +-DGSLLGKVIRYTQEDVTKYGPVTGRNLANGMTVKSLCEAAITYSDNCAANLLLKELGGP +TAISRFSRSIGDPVTRLDRWEPELNSAEPGRETDTTSPRAIGQSYARLTLGHALNRDDAD +QLTNWLLANTTGGNRIRAGLPAAWRWGDKTGTGRYSTTNDVGIAFPPGRAPIVIAVLSTK +KDPEGGADEPLVAKTAELVAASf +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=A0A132ENU2_9BURK +--AAQSDLAALEKASNGRLGVAALDTSNGARV-AHHARERFPLCGTYAVVAAAAVLARGS +LDATLLPRRILYRRYDVVAGSPVTENHVDTGMTIAQLCAAMLQAGDKGAGNLLMGVLGGP +QAVTSFAHESGDTTFRLDRWEPELNAAAPGDERDTSTPVAMVDTLQRLLLGDLLREPQRA +QLIEWMVGGARGAAGIAAGVPPGWRVADKSGTGGYGTTTDVAVVWPPSRAPLVMAVSFTQ +PRADAAARADVVASAARIAAN-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00021E08F6 +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSMARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGEDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDEDQRGAVLARVGAL----- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio hyugaensis TaxID=1534743 RepID=UPI0005F0BBE9 +--KLNEDLTAIEEHISGRIGVSVWDTQTEEHW-DYRGDERFPMMSTFKTLACATMLKDMD +NEKLDKNATAKVEERNMVVWSPVMDRMVGQSTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTMFLRNIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLQTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRAGTGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] carbenicillin-hydrolyzing class A beta-lactamase CARB-44 n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0005426728 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNTLSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A6B6D1 +-----NELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRSL +SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP +EDPTSTKGKPTIAAAARIVLRAf +>[subseq from] class A beta-lactamase n=1 Tax=Herbidospora daliensis TaxID=295585 RepID=UPI0007824F5C +-----ADLRALETSFKGRIGLYAIDTATGKTI-AYRSGERFPLASTFKAVLAAAVLDKKP +---DILGKRISIKKKDLVDYSPEVEKHVGSSMTVAALARAAVTKSDNAAANLLLKQVGGP +KGLTRYFRGLGDHVSRLDRTEPGLNRWSPRELRDTTTPAAVGRDLRDLAAGDALDAGDRR +IFTGWLVANETGDKRIRAGLPKSWRVGDKTGTGGYGTANDIAIIWPKGSKPIIMAIYTNR +TDRNAAADDSVVARTATIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000751EEF1 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. EAG2 TaxID=2056495 RepID=A0A2N3K2K5_9ACTN +--DAERRLARLERESGIRLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RDGEFLSRRIFYTQDDVERGAPETGKNLANGMTVEELCKVSITASDNCAANLTLRELGGP +TAVTRFVRSLGDRVTRLDRFEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGLPEDWVLGDKTGAGHYGTNNDAGVTWPPGRPPIVLTVLSTQ +TEQDAVRDDGLVADAARVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075917CD +---AQLQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase OXY-2 (Beta-lactamase/transpeptidase-like, 38-293) n=1 Tax=Magnetospirillum sp. XM-1 TaxID=1663591 RepID=A0A0U5HXS6_9PROT +--RLAAPLAELEYHSGGRLGVMVKDVERGETA-GHRADERFALCSTGKVPTVAAALARHD +AEGGWLERQIPVAAADLVSWSPVVERRVGGVMTVAELCEAALTQSDNSAMNLLLRLLGGP +QAVTGYLRGLGDAETRLDRVEPELNEAALGDARDTTTPAAMLATLEKLMLGDALSPAGRA +RLVGWMAANRTGDRRLRASLPEGAWAAEKTGSGERGSTNDIGAFRLAGRGVVLIAAYLTD +TTLPANRRDLVIADVARTVV--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q9X5A7_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMASSLARFAVGNGLQPASRQ +QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAVWVVTAYLQG +ASVDDDQRAAVLARVGTL----- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075FBA1F +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGMPSDWRVAGKTGTGGYGTTTDVAVVWPPSHAPLVIAASFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio sp. OULL4 TaxID=1904360 RepID=UPI000987D10E +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLALQARDQLIAQISQLILEHy +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011211586 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDSYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. QGD 101 TaxID=1867256 RepID=UPI000C7F68BF +-----ASVAALEPRHNALIGLYAVNLDTGRTV-ANRADEMFAMCSTFKTYAAARVLQMVG +RGQLSLDNRVFVDSAEIVANSPVTEARAGGEMTLAELCQAALQRSDNTAGNLLLKAIDGP +PGITAFARSIGDERTRLDRWETELNSAIPGDPRDTSTPAALATGYRALLVGDVLNPPQRR +LLEDWMRANQT--SSMRAGLPPGWTTADKTGSGDYGSTNDVGIAYGPDGQRVLLAIMTRS +QANDAANLRPLIGEVTALV---- +>[subseq from] Beta-lactamase n=2 Tax=Roseovarius TaxID=74030 RepID=A0A5E7ZQQ4_9RHOB +--HLAATIDRIEQELDARVGVVIRESGSDWIV-SHRAEERFLMASTFKTMLCGAVLHRVD +EGDLDLEERIAIEAAEVLEYAPVTEKMVGETMSVGELCHAALDMSDNAATNLLIDRIEGP +QSVTAFLREIGDPVSRLDRREPDVNTFAPDDPRDTTTPEAMVSTMVTLLTGDALSPQSRA +QLVDWMSDGGVTGALIRASTPAGWHVADRSGSGNF-NRNIVAMVTPPDREPYFIAIFLSD +ADADFNTRNGAVIELSKAVMQ-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. TD3 TaxID=1641707 RepID=UPI0009534CC0 +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAYVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGEDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDEDQRGAVLARVGAL----- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00084A8BF8 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILERy +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI000927CFFA +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPASTKGKPTIAAATRIVLRAf +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio jasicida TaxID=766224 RepID=UPI0005EE01B7 +--KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD +SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMINTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI00088327BE +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMAGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PQADAAARADVIASAARIAA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00112142C5 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSGSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. UM_WWY TaxID=1370121 RepID=UPI000407DD95 +---LDDQIAGLEKRNNASIGVFAANVDSNRTV-AHRADETFAMCSTFKGYAAGRVLQQVD +RGQLALDTRIFIDPSAIVANSPVTEERTGADMSIGELCQAALQHSDNTAGNLLLKLIDGP +PGITAFARSIGDNRTRLDRWETALNSAIPGDLRDTSTPAALGAGYRAMLTGDVLSPPQRQ +QLEDWMRGNET--SSMRAGLPVGWTSADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS +RADDAANLRPLIGELTALVV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-495 TaxID=1609133 RepID=A0A0F4JE14_9ACTN +--ELADRLCALERLHSARLGVFAQDAATGRNV-AYRAHELFPMCSTFKTIAVAAVLRDLD +RDGTFLAERRHYTTRDVAEYAPITGLNLEAGMTVEELCSAAIRYSDNAAANLLLRELGDP +EAITHFCRSISDRVTRLDRWEPALNSAEPGRPTDTSSPHAIGRTYARLTLGKALDTADRQ +RLTRWLLTNTTGANRLHAGLPTTWTVAEKTGTGNYGTTNDVGVTWRPDGGPIVVSVLSTK +QIADAPADEPLIAETARLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 852013-50091_SCH5140682 TaxID=1834109 RepID=A0A1A0XH03_9MYCO +---LDDQIAGLEKRNNALIGVFAANVDSNRTV-AHRADDTFAMCSTFKGYAAGRVLQQVD +RGQLALDTPIFIDPSAIVANSPVTEERTGADMSIGELCQAALQHSDNTAGNLLLKMIDGP +QGITAFARSIGDNRTRLDRWETELNSAIPGDLRDTSTPAALGSGYRAMLTGDVLSPPQRQ +QLEDWMRGNET--SSMRAGLPAGWTSADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS +RADDAANLRPLIGELTALVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces monomycini TaxID=371720 RepID=UPI0004AA0E98 +hpAATRRLRELEREHQARIGVFALNLATGATL-LHRAHERFPMCSVFKGLAVAAVLRDLD +HDGTQLSRVIRYTEADVRKHVPVTSRHVADGMSVRDLCDAAVRYSDNCAANLLLRELGGP +TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAVARTYRRLVLGNALDRPDRA +LLTDWLLRSTTSVERFRAGLPKDWKVADKSGGGSYGTSNDAGIAWTPDGTPIVLAAFTHK +PAPNASGDTPLIIKTATVM---- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium oceanosedimentum TaxID=465820 RepID=UPI0009E91529 +--ATSRAFAALEEQYGARVGVVAIDTADGGSL-GYRADERFAFASTNKAFIAAAVLDASS +--TDDLDDVVRYDRSDLLSYAPVTSQHVDEGMTVRALVDAALRESDNTAANLLVERLGGV +GGVSRWLRGIGDDVTRVDRVEPDLNTAVPGDPRDTTTPAQSATDLRAVLLGDALDPDDRA +LLRSATAGTTTGDGTIRAGVPDGWSVADKTGTASYGVRNDIAVVEPPGRDPIVLVVFTTR +DGADAEPSDALVAAATRVAVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FDFC48 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGSPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +AGADAAPRADVVAEAARIAA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111D6328 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPAYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium smegmatis (strain MKD8) TaxID=1214915 RepID=A0A2U9PPQ0_MYCSE +---VDDRIADLERRNNASIGIYAVDLDSNRTV-AHRADDSFAMCSTFKAYLAARILRGAE +RGELSLDDRVFVDPAALLSNSPITETHAGGEMTLAELCQAALQRSDNAAANLLLKQIGGP +AEITAFARSIGDQRTRLDRWEIELNSAVPGDPRDTSTPAALAGGFRAMLTGDVLGPPQRQ +LLDEWMRANET--SSLRAGLPDGWTSADKTGSGDYGSTNDVGIAYGPQGQRILLALMVRT +RGPNADGFRPLIGELTALV---- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis flavescens TaxID=758803 RepID=A0A1M6BSI5_9ACTN +---VSAELAALEEEFDAHLGVYAVDTGTGAEI-AHNADDRFAYASTHKALSAGAILERNT +--LEEMEEVVTFTEDDLVGWTPVTEQHVDTGMTLLEVIDAAVRHSDNTAANLALEELGGP +QGFEDALRGIGDEVIEAERWEPDLSEHTPGEERDTSTPRAMAASLEAYTLGDVLPEEKQD +VLIDLLLRNTTGDATIRAGVPEGWTVGDKTGSANYGTRNNIALLWPAEGEPIVLAIMSSR +DEEDAERRDELIAETAGVVAD-- +>[subseq from] BCL family class A beta-lactamase n=1 Tax=Bacillus clausii TaxID=79880 RepID=UPI000BA7B6B3 +-----AVFKALEEEYAARLGVFALDTGTGQTV-SYRSDERFTYASAHKPLAVAVLLQQKS +--IEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANFIFDEIGGP +EGFKEGLRAIGDTVTEPERIEPELNHVEPGEIQDTSTPEALAKSLQEFALGEALPADKQE +LLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILLPPEKEPIILAVLSSK +DEKDAEYDDELIAKATEEVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075EF64B +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. GW247-27LB TaxID=2012632 RepID=A0A270BFB3_9SPHN +----AGRLAALEKQSGGRLGVAFLDPASGRTT-GHRADERFALCSTFKWPLSAVVLKAID +EGKLTLDRRVPYGKADLLPNSPVTQKNVAKGMTVAELMEATITASDNAAANLLLPLVGGP +EAVTRQFRAWGDPVTRLDRAEPHLNLVGEGEVRDTTTPAAMTALLRTTLLGDALSPASRT +RLIDWGVATTTGPQRLRAGLPAGWRIGHKTGTAMMNKYNDIAIAFPPKGAPLLIAAYYEG +PVATRDADQAVLAAVGRLAAE-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011224BE2 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPDDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DDB873 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAGLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis eurytherma TaxID=196083 RepID=A0A3N2GQT5_9PSEU +-----VDFAGLEARFDARLGVYAIDTGTGREI-AHRADERFNYASAIKSLLAGAVLRRNV +----DLDKVVTYTDADIQPNSPVTKDR--RSVTVREAAEAALLQSDNTAANLLFAEVGGP +AGLAAVLREIGDTTTHPDRLEVELNSAIPGDVRDTSTPRAMAGSLRAFLLGDALPADKRD +LLVGIMRRNKTGTELIRAGVPSEWPVADKTGTGDYGTRNDIGVIWPPGRAPIVLALMSSR +TAADASYDNKLLAEATSRVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium oceanosedimentum TaxID=465820 RepID=UPI000736EB58 +--ATSRAFAALEEQYGARVGVVAIDTADGGSL-GYRADERFAFASTNKAFIAAAVLDASS +--TDDLDDVVRYDRSDLLSYAPVTSQHVDEGMTVRALVDAALRESDNTAANLLVERLGGV +GGVSRWLRGIGDDVTRVDRVEPDLNTAVPGDPRDTTTPAQSATDLRAVLLGDALDPDDRA +LLRSATAGTTTGDGTIRAGVPDGWSVADKTGTASYGVRNDIAVVEPPGRDPIVLVVFTTR +DGADAEPSDALVAAATRVAVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00031EE049 +-----NELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL +SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP +EDPTSTKGKATIAAAARIVLRAf +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. BK308 TaxID=2512170 RepID=A0A4R3CN52_9ACTN +--ALEGELRDLEKRYAARLGVYARNLRTGQVV-AHRARERFALCSTFKAFAAAAILRDHG +-HCAPLDRVIHYPPADVVLNCPVTGKHVDTGMTVGDLCAAAIQYSDNAAGNLLLRQIGGP +EGLTRFFRSIGDPVSRLDRWETELNSAVPGDLRDTTTPEAVGGGFTRLTLGRSLADADRE +QLVTWLKGNTTSGERFRRGLPRNWVVADKTGTGDYATGNDLGVAWTGRGTPVVLAVLSSK +STRDAAVDNGLIADTARLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=A0A0D1LM52_BRAEL +--SIEHRLKDVEVQSRGWLGVALLDTATGKLI-GNRIDQRFAMCSTFKALAVALVLARVD +RGEEQLDRRVVFSEHDLVPPSVATQPHVGPGMTVAELCEAAVTVSDSTAANLLLASFGGP +AALTAYLRSLGDPVTRLDRVELDLNIVKPGEQHDTTSPAAMARTLQRLLLGDALSEPSRA +RLTGWMAGAKDATTRLRAGLPQGWRIANKPGTWKGIATNDVGVIWPPGRAPIVVAAYLAD +APTPVATQEAILAEIGRIVAE-- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio rotiferianus TaxID=190895 RepID=UPI0003A4CA22 +--KLNEDLAAIEQHIGGRIGVSVWDTQNDQHW-DYRGDERFPMMSTFKTLACATMLNDMD +SEKLDKNATAKVEERNIVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +NGVTRFLRSIGDGATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QD19_STEMA +-----ADFAALEKASGGRLGVTVLDTGNGRRIgGHRQDERFPMCSTFKSMLVANVLSLAD +AGRVSLDTRVSIAGKDLLSYAPVARRHVGKDLTVRDLCRGALTISDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMAASLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hyaluromycini TaxID=1377993 RepID=UPI000B5CED6F +----TARLRALEREHRARLGVFAWDTGSGARL-GYRSGERFPMCSVFKTLAVAAVLRDLD +--EGVLTEVVHYDEGDVERGAPVTGRNLAAGMTVEELCAAAVSYSDNAAANLLLEQLGGP +VAVTRLCRSLGERVTRLDRWEPELNSAEPGRVTDTTTPSAVATTYVRLTVGHALDGADRR +RLTGWLLANTTGGERIRAGLPADWRVGDKTGTGGHGTANDVAVAWPPGRAPVVVAVLSTH +ADAAAEPDSPLVRAAATVVADTf +>[subseq from] UPI000FF87531 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI000FF87531 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCATFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis japonica TaxID=208439 RepID=A0A075V3A2_9PSEU +---ASTDFEQLERTFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP +--VAELDRTVTYGQQDLVTNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP +EGLNAVFRGIGDTTSHADRIEPALNDTAPGDSRDTSTPRALAVGLRAFALGDALPEDKRK +ILVDMMRANTTGDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVVSVLTDR +AEKDAKIDNKLLADATAAAIK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Kitasatospora sp. Root187 TaxID=1736486 RepID=A0A0Q8P8R3_9ACTN +---ITSRLRELEQQHSARLGVFARNMRTGRTV-AYRADERFPMCSLFKTVAVAAVLRDLD +HDGEFLAKRIRYTAEYVKKYSPRTGRNLESGMTVAQLCDAAICYSDNTAGNLLLRELGGP +TALTRFCRSIGNGRTRLDRWEPELNSAEPSRVTDTTTPRAIGRTYAHLTLGDALTPQDRE +RLTGWLLANTTSGERFRAGLPGDWILADKTGGGRYGGNNDAGVTWPPDGGPIVMAVLTTK +HVEDAPADHPLVARTAAMLA--- +>[subseq from] Carbepenem-hydrolyzing beta-lactamase KPC n=2 Tax=Mycobacteroides abscessus TaxID=36809 RepID=X8DQA0_9MYCO +-----NELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL +SEPGLLDRRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007573065 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRLRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE7681 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +AGADASPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00092C1143 +----------------------------------------FPMCSTSKVMAVAAVLKQSE +TQKQLLNQPFEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNRAGAASIRAGLPTSWTVGDKTGSGDYGTSNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0005DD9877 +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPASTKGKPTIAAATRIVLRAf +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis australiensis TaxID=546364 RepID=A0A1K1SAS7_9PSEU +------DFAPLEHDFDARLGLYAVDTGSGREV-AHRADERFGYASTHKAFSSAAVLQRTG +--LDGLAKILNYTRTDLQPNSPVTEQHVTTGISLRDAIDAALRYSDNTAANLLFRELGGP +PGLAAALRGVGDTTTHVDRVEPGLNDLAPGDVRDTSTPRAMARGLRAFTLGDALPPEKRQ +VLTDTMRANTTGAALIRAGAPAGWAVADKTGTGGYATRDDIAVVWPPGRAPIVLVVMSDR +KTQDAPHDDRLIAEAAKLAF--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001124B06C +--KLNEDISLIEKQTSGRIGVSVWDTQKDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Bla protein n=1 Tax=Burkholderia sp. MSHR3999 TaxID=1542965 RepID=A0A0D0GFC5_9BURK +---AQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVVWPPSHAPLVIAASFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=UPI000DFA4D40 +--------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD +RKALALSASTQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP +QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE +QLMQWMRDDKVADSLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ +TPATMAQRDAAIVRIGESLF--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus kochii TaxID=859143 RepID=A0A248TH22_9BACI +------KFAQLEEKYGAKLGVYAIDTGNEETV-AYQEDERFAYASTFKALAGAVLLKENP +--ISILDEKRMYTKEDLVTYSPITEKYVDEGMTLREIAKAAMQYSDNTAGNLLFAELGGP +DQLEEALRAIGDDVTEMDRLETELNEATPGDTRDTSTPKALATNLRIVGLTDELSEEKRE +IFQEWFKGNTTGDTLIKSGVPTDWIVGDKSGAASYGTRNDIAIVWPPNDEPIVIAILSNK +QEKEAEYDDQLIGEATEIVLE-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium chitae TaxID=1792 RepID=A0A448I6C8_MYCCI +-------LAGLEDRYGARIGMTAVDLASGKSL-AHRADQRFAMCSTFKTYAAARVLQLTE +QGRLHLDTQTPITESDIVTHAPVTGTKVGQSMSLADLCAAALMESDNTAGNLLLRAIGGP +PAITEFARSVGDDRTRLDRWETELNSALPGDPRDTTTPGALALGYREVLTGTALAEASRE +QLLAWMKANITSDKRFRAGLPAGWTSADKTGGGDYGTTNDAGLLLGPKGQRIVLVVLTRS +LDPEAGPYNEAIAETVR------ +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium madagascariense TaxID=212765 RepID=UPI00138D7D5F +--RAQDALAQLEARARVRLGVFALDTATQAST-GYRADERFLLCSTGKVLDVAAILKRSE +TDPGLLDRVITYGPSDVLAYAPVTSQHVTDGMTVAALCDAAITVSDNTAANLLVELLGGP +PAVTAFARGIGDGVTRVDRLEPDLNVTTPGDPRDTSTPRQMALDLQTLVLGDGLADDSRQ +RLTDLLKANTTGAQTIRAGLPSDWVVGDKTGSGAQGEGNDVAVAWPPNRPPLLIAIYVAP +VDLAADDVHRVIAEAARIA---- +>[subseq from] Beta-lactamase n=1 Tax=Plantactinospora sp. BB1 TaxID=2071627 RepID=A0A2R4FT08_9ACTN +----HDQLLRLEREFDARLGVYALATGTGTVV-AHRADERFAFCSTFKGLAAAAVLARNP +--LTHLDTVVRYARRDLTANAVITRRHVDRGMTIRQLCDAAVRYSDGTAGNLLVRDLGGP +AQLTAYARSLGDTVTRMDRIEPAITQATPGDPRDTTSPRAIGTDYQKILLGDALVPEKRA +FLRDLLERNATGARRIRAGVPKGWTVADKTGTGGYGTVNDIGVVWPPNSPPLVIAIMSSR +AARDADHDQAIIARATEYAV--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. DAIF1 TaxID=2546450 RepID=UPI0010710114 +---AAADFAALEKACRGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDPALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLMLGNALRPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDMAVLWPVGGSPWVLTAYLQA +GTISFEQRAAVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia donostiensis TaxID=1538463 RepID=A0A1W0ARC9_9NOCA +----HARLAELERDYGARLGVYALATGTGDII-DYRADERFAFCSTFKGLAAAAVLHRNP +--LSHLDTVVHYTEADLLKNATITPGHVAEGMTIRALCDAAIRYSDGTAGNLLLRDLGGP +SELTAYARSLGDTVTRMDRVEPDITEATPGDPRDTTSPRAFGTDYQHIVLGEALAPEKRA +FLRDLLERNATGARRIRAGLPRGWVVADKTGTGDYGTLNDIAIVRPPDSAPLVIAIMSSK +ATVDAAYEPALLAEAAEYVA--- +>[subseq from] BCL family class A beta-lactamase n=1 Tax=Bacillus clausii TaxID=79880 RepID=UPI0009ED85A6 +-----AVFKALEEEYAARLGVFALDTGTGETV-SYRADERFTYASAHKPLAVGVLLQQKS +--IEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANLIFHEIGGP +EGFKEGLRAIGDTVTEPERIEPELNHVEPGEIQDTSTPEALAKSLQEFTLGEALPADKQE +LLIDWLIGNTTGDALIRAGVPEGWDVGDKTGAGSYGTRNDIAILWPLEKEPIILAVLSSK +DEKDAEYDDELIAKATEEVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00115BFE30 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGCR---------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBW8_STEMA +----ATDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE +RTPALLGTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPCRVNAYLQA +SAISYEQQAVVLAQVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Actinoplanes sp. N902-109 TaxID=649831 RepID=UPI00059F7D06 +----QRAFAALESQFDARLGVYALDVKSGHAV-AYRADERFAYASTYKALAAGALLAHTS +--DADLDDMVTYQRADLVAHSPVTGKKLADGISIGDAAEAAVRVSDNTAANLVLRELGGP +AGWEKDLRGVGDTVTEAARTEPELNAATPGDKRDTSTPRALAADLRAYVLDDALDAGDRS +TLTRWMTGNATGNTLIRAGVPKGWTVADKSGGGQYGTRNDIAVVWPEPDRPLVLAVLSSR +AGADADYDDALIARAASVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0003166A66 +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDLTSTKGKPTIAAATRIVLRAf +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio hyugaensis TaxID=1534743 RepID=UPI000CE529B3 +--KLNEDLTAIEEHISGRIGVSVWDTQTEEHW-DYRGDERFPMMSTFKTLACATMLKDMD +NEKLDKNATAKVEERSMVVWSPVMDRMVGQSTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTMFLRNIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLQTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRAGTGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium aurum TaxID=1791 RepID=A0A448INC5_MYCAU +--AIDERIAALGRRHNAQIGLYAVDLNTQNSL-SYRDTERLAMCSTFKAYAAAAILQRAQ +RGQLTLNDPVAIEAGDIRPHSPVTEPRVGTTMTVAELCQAAVQQSDNAAANGLLGVLGGP +QAITEFARSIGDDQTRLDRWEIELNTAIPGDPRDTSTPRALGSGYRAVLTGDVLAPAGRQ +QLVDWMLANQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVVYGPAGQRVLLAIMTRS +ATPDAPSLRPLIGEVASLVLA-- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio owensii TaxID=696485 RepID=UPI0005EF10DD +--KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD +SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDTLSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] UPI000FF874C9 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI000FF874C9 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCCTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075DDB26 +--AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVAAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLRELQRA +QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces globisporus TaxID=1908 RepID=UPI0004CA9F39 +-----ARLRRLEREHTARLGVFARDMRTGRTV-AHRADERFPMASVFKTLAVAAVLRDLD +HDGEFLARRVRYTEAYVARHSPVTGSNVSGGMTVSGLCDAALRFSDNTAANLLLERLGGP +AGVTRFCRSTGDRVTRLDRWEPELNSAEPWRVTDTTTPYAIGLGYARLVLGDALEPHDRE +RLTGWLLRNTTSTERFRRGLPADWLLADKTGSGRYGGAGDVGIAWRPDGTPIVLAVLTTR +PEEDAPADNPLVAGTATLLAE-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI000CE94695 +-sQLNEDIALIEQQTSSRVGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRSIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLIAQISQLILQKy +>[subseq from] Beta-lactamase 2 n=1 Tax=Streptomyces cacaoi TaxID=1898 RepID=BLA2_STRCI +----AAELKALEDEFDVRLGVYAVDTGSGREV-AYRDGERFPYNSTFKALECGAVLDKHT +--DREMDRVVKYSEDDLVDNSPVTEKHVEDGMTLTALCDAAVRYSDNTAANLLFETVGGP +KGLDKTLEGLGDHVTRMERVEPFLSRWEPGSKRDTSTPRAFAKDLRAYVLGDVLAEGDRK +QLTTWLRNNTTGDGLIRAGVRQGWVVGDKTGTGSYGARNDMAVVWRPDGRPLVLNVMVHG +HTKDAELDSELIARATEVVAD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A105ZJQ6_9BURK +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNLARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. RV163 TaxID=1661388 RepID=UPI00069EC0AD +-------FALLAEEFGVRLGVYAVDTGTGREV-GFHADERFAYCSTFKVLAFGAVLDRTP +--VEALDRVVTFSEADLVFHSPVTHEHVASGMTLRGIGDAALRHSDNTASNLLVEELGGP +PELEKALRGIGDDVTNVDRLAPEMAEAVPGDVRDTSTPRAMAASLRAFALGDVLTEERRE +VLVGMMRANTTGDGLIRAGVPEGWDVGDKTGACGYGTRHDIGVLWPPGGAPLVLAVMSSR +DEAGAGYDDALIARATQTALE-- +>[subseq from] Beta-lactamase n=1 Tax=Lentzea albida TaxID=65499 RepID=A0A1H9PF51_9PSEU +---ITGRLRELERQHHARLGVFATDTGTGRTV-LHRADELFPMCSTFKTIAAAAVLRKDR +-DGTLLGKVITYTKSDVDKYGPITGKNLANGMTVSALCEATITYSDNCAANLLLKELGGP +TAISRFCRSIGDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGQSYARLTLGHALNSNDSD +QLTKWLLANTTGDNRLRAGLPAAWRWGDKTGTGSYGTTNDVGIAFPVGRAPIVIAVLSTR +ESPTGGADEPLLAKTAELVAATf +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. SLBN-118 TaxID=435993 RepID=A0A542QJD1_9ACTN +---ISGALSNLEREHSARLGVFARNTVTGRSV-LHRADELFPVCSVFKTIAAAAVLRDLD +RRGEFLAKRIRYTDKDVKDYGPITGEHLAGGMTVAELCAATIEYSDNAAANLLLHELGGP +TAITCFCRSIGDTTTRLDRFEPKLNSAEPWRVTDTTSPCAIGRTYEKLVLGDALTRPDRQ +QLTAWLLANTTSGARFRAGLPKDWTLADKTGTGEYGTTNDVGVAWTPDGAPVVLAVLSTK +HDAHCPADEPLVAKTAELLT--- +>[subseq from] Beta-lactamase n=1 Tax=Streptosporangium subroseum TaxID=106412 RepID=A0A239NDI5_9ACTN +--EARRQLRALEASFKGRIGAYALDTATGKTV-TYRSGERFPLLSTFKASAAAAVLHKAR +TDPGLMDRVIHWKKSEVKANSPVTEKHVKDGLSVARLCEAAITQSDNTAGNMLLKQIGGP +AGLTRYFRTLKDPVSRLDRWETELNEWTPKEKRDITTPAAMGRNLRGLATGAALNAKDRA +RLNGWLRANKTGDERIRAGLPATWTIGDKTGTTSYGAANDIAVVWPGKGAPLIMAIYTNR +RAAGALSDNKVIADTAAILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758CEC3 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075DFAD6 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Clostridium butyricum TaxID=1492 RepID=UPI0002D1F93F +---YNSEFSKIESDYGVKLGVYAYDTEKNKEI-TYNADERFAYCSTSKALLAGSILEKYP +--VDKLKEVIQYEEKDLLSYAPVTKDNLNKGMTIEELCEAAVRLSDNTAANLLFNLIGGP +SGFKESLNKLGDNVTEPERIEPELNSAIPGEIRDTSTPRQLALDLKEYISGNILTDDKKA +IFIDWMSGNSTGDNLIRAGAPNEWIVADKSGAGDYGTRNDIAIVTPPNGKPIFLAILSNK +NEEDAKYDDETIAEASKVVFDYf +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001375B6DA +--KLNEDISLIEKQTSGRIGVSVWDTQMDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKTTRLDRLEPHLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI000471E1A0 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKQDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D5496 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHDSGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=UPI000C9C9EA1 +--DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD +RGTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP +EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTATPRSVLSTLHAALSGTMLSGSSSA +QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE +TDADFAQRNQAISDIGRAMI--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 844.5 TaxID=2485140 RepID=A0A3N1KU34_9ACTN +---IDGRLRALERKHSARLGVFAYDTGTGRVI-RYRADELFPMCSTFKTIAVAAVLRDLD +CDGRFLAEVLHYTEEYVTQYAPITALNVADGMTVADLCAAAIDHSDNGAAKLLLRELGGP +SAVTRFCRSLGDRVTRLDRWEPELNSAEPGRITDTTSPHAIGRTYARLVLGDVLAAPDRH +RLTGWLLADTTSGNRFRAGLPQDWTLADKTGTGDYGTTNDVGITWPPGRKPIVMAVLSTT +LSPAAPADEPLLAETATLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Plantactinospora sp. BC1 TaxID=2108470 RepID=UPI000D151BA2 +----HDQLLRLEREFDARLGVYALATGTGTVV-AHRADERFAFCSTFKGLAAAAVLARNP +--LTHLDTVVRYARRDLTANAVITRRHVDRGMTIRQLCDAAVRYSDGTAGNLLVRDLGGP +AQLTAYARSLGDTVTRMDRIEPAITQATPGDPRDTTSPRAIGTDYQKILLGDALVPEKRA +FLRDLLERNATGARRIRAGVPKGWTVADKTGTGGYGTVNDIGVVWPPNSPPLVIAIMSSR +AARDADHDQAIIARATEYAV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus lehensis G1 TaxID=1246626 RepID=A0A060LZ65_9BACI +-----AVFSVLEDHYDARLGVYALDTGNGQTI-AYNEDERFAYASTHKALAIGVLLQQLS +--LDELDTQILFSEADLVTYSPITEQHVETGMSLHEISDASIRYSDNTAANLIFNEIGGP +SGFKEALREIGDEVTEPERMETELNDVKPGETRDTSTAKALAESLYAFSLGDALDEEKQT +LLNDWLIHNTTGDALIRSGVPEGWLVGDKTGSASYGTRNDIGIIWPPDEDPIVIAVLSSK +EQADAESDDALIADATEAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia pseudovaccinii TaxID=189540 RepID=UPI0007A376B3 +------QLAGIEQQHQARLGVFAVDTGSGRTV-GFRQDERFAMMSTFKTLACAALLHEHP +LATGYFDQIIHFTEADAAAGSAVTGTRIDSGMSVSELCDAAITRSDNAAGNELLKLLGGP +QALTRFLRSIGDQISRLDRTEPTLNTAIPGDERDTTTPAAIAADYRALTVGDALAAPERE +QLTAWLIATTTGGARIRAGLPNDWKTGDKTGTGDYGSANDVAVTWPVGSAPIVIAVLTTH +SSPDAQADNALVAEATEEA---- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 455mf TaxID=1761812 RepID=A0A1I2IFC4_9MYCO +---VDDQIAELERRDNALIGLYAANLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMVG +RRQISLDNRVFVDPEAIVPNSPVTETHAGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAVLAGDALSPPQRR +QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPNGQRLLLAVMTRS +QADDADNLRPLIGELTALV---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia vinacea TaxID=96468 RepID=UPI0005946BFF +------QLAGIEQQHQARLGVFAVDTGSGRTV-GFRQDERFAMMSTFKTLACAALLHEHP +LATGYFDQIIHFTAADAAAGSAVTGTRIDSGMSVSQLCDAAITRSDNAAGNELLKLLGGP +QALTRFLRSIGDQVSRLDRTEPTLNTAIPGDERDTTTPAAIAADYRALTVGDALAAPERE +QLTAWLIATTTGAARIRAGLPNEWKTGDKTGTGDYGSANDVAVTWPAGSAPIVIAVLTTH +SSPDAQVDNALVAEATKE----- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. T44 TaxID=2686304 RepID=UPI001317F651 +---TDGEFSELERRHGARIGVFARNLRTGLTV-AHRAGERFAMCSTFKAFAAAAVLRDHG +-DCAPLGAVIHYPPHDILSNSPRTAEHVDTGMTIADLCAAAIQYSDNTAGNLLLRQIGGP +AGLTRFFRSLGDEVSRLDRWETDLSSAIPGDLRDTTTPGALGRSFERLTLGRALTGGDRA +RLVGWLKGNTTSAARFGAGLPRDWVLADKTGTGDYGTANDTGVAWTTRETPLLLTVLSAK +TAQDASADDALVAQAARILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus lehensis TaxID=300825 RepID=UPI00056DB11E +-----AVFSVLEDHYDARLGVYALDTGNGQTI-AYNEDERFAYASTHKALAIGVLLQQLS +--LDELDTQILFSEADLVTYSPITEQHVETGMSLHEISDASIRYSDNTAANLIFNEIGGP +SGFKEALREIGDEVTEPERMETELNDVKPGETRDTSTAKALAESLYAFSLGDALDEEKQT +LLNDWLIHNTTGDALIRSGVPEGWLVGDKTGSASYGTRNDIGIIWPPDEDPIVIAVLSSK +EQADAESDDALIADATEAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia brasiliensis ATCC 700358 TaxID=1133849 RepID=K0EP12_9NOCA +---RHDRLSELERKFDARLGVYALDTASGAII-AHRAEERFAFCSTFKGLAAAAMLQRNP +--LSHLDTVVRYTEADLTKNAAITPQHVATGMTIRDLCDAAVRYSDGTAGNLLLRDLGGP +AELTAYLRGLGDPVTRMDRIEPAITEATPGDPRDTSSPRALGTDYQRIVLGDALPDDKRA +FLRDLLERNATGAGRVRAGVPQGWKVADKTGTGDFGTLNDIAIVWPPDRAPLVISLMSSK +ATADAEYDQALLAEAAAYVVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces viridochromogenes TaxID=1938 RepID=UPI0005663D8F +--------RSLEREFDARLGVYALDTGTGRSV-GYRADDRFAYASTFKALAAGAVLRKFG +--TDGLDRVVRYSRDDLVADSPVSENFVKTGMSLRGLCAATLWYSDNTAVNLLFDELGGP +DGLEKVLEEFGDDVTEMDRYEPDMSEGAPGDIRDTSTPRAMAGSLRAFLLGDALKADERE +LLRQWMTTNMTGRTLIRAGVPDGWDVADKSGTAGYGGRNNIAVVWPDDGNPIVMAVMSSR +DKQGAERDDALLAKAAAVAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Kibdelosporangium aridum TaxID=2030 RepID=A0A428Z6B3_KIBAR +------DFKALEARFDARLGVYAVDVTTGKSV-AHRENERFAICSVFKAYAAGALLKAHP +LSSGFFTQTIRFTQAEVVANSPVTGARVATGMTVAELCEAAITKSDNTAGNQMLKLLGGP +TKLTDFARSIGDPVTRLDRWETELNVVPRGTEQDTTTPSAIANAYRGLVVGDILAEPERK +QLKDWLIANTTGDARIRAGLPKGWVTGDKTGTGSFAAANDVAVTWPSPEKPIVIAILTDK +ADENAKYDNALIAEATKAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. KBS0801 TaxID=1179675 RepID=UPI00110E2A6A +--AAQAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP +QAVTSFAHESGDTVFRLDRWEPELNLAAPGDERDTSTPVAMVDLLQQLLLGDTLREAQRA +QLTEWMTGGARGATAIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIAT--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseofuscus TaxID=146922 RepID=A0A3R8QCH6_9ACTN +-----GELADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP +AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALATPDRE +RFVTWLKGNTTSGARFRAGLPGGWTIADKTGTGDYASANDIGVAWTARRTPVVLAVLSTK +EGKNAPVDEALIAEAARIAAR-- +>[subseq from] Beta-lactamase n=2 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0004E98156 +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFAAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Tatumella sp. UCD-D_suzukii TaxID=1408192 RepID=UPI000472D6AF +------QAKLAEQQLHARVGFAELDLATGALReSYRSGERFPMMSTYKVLLCGAVLARID +SGREQPERRIMYRQQDLEKYSPVTKQYLNEGMTIAGLCDAAITMSDNTAANLLLSSIGGP +QALTRFLRQTGDPMTRLDRQEPELNEALPGDPRDTTTPEAMARTLRNLLSGKILTAASQQ +QLLHWMIADQVAGPLLRKVLPAGWFIADKSGAGEHGSRGIIAVTGPAGKPSHIVVIYITD +NDASMDVLNRQIAGIGAAMF--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00066BB1FE +-----ADFAALEKASGGRLGVTVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +SGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHAGPAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A0I9QQ20_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNHGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium houstonense TaxID=146021 RepID=UPI00082AD4FC +---IDDQIAELERRHHALIGLYAANLDTGRTL-THRPDDMFAMCSTFKGYAAARVLQMVG +RGQLSLDQRMFVDRAAIVPNSPVTEAHVGSEMTLDQLCQAALQRSDNTAANLLLKNIDGP +AGITAFARSIGDERTRLDRWEVALNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRR +QLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGVAYGPDGQRLLLVMMTRS +QA-DDPKADNL------------ +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf100 TaxID=1736252 RepID=UPI000700239C +---ATNTLREIERRVGGRLGVSVGKSNAPPLL-GHRADERFPMCSTFKVLAAAALMARVD +AGTESLDRALPYGEGDLLKYAPVTRKALEAAISVADACAAAVEWSDNTAANLMLNVLGGP +SALTGWLRGIGDPTTRLDRTEPDLNTAIPDDPRDTTTPDAMRTTLEQILVGTALSPATRT +RLDGWLAAGRTGSKRLRAGIPPDWKVGDKTGSGDNGTYNDVAILRPPGQAPILAAVYLTG +STAPVTDVDAAYAEIGRMIAE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A2Z6A9G8_SHISO +------------------------------------------MMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLI--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A85931 +-----NELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL +SEPGLLDRRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis coloradensis TaxID=76021 RepID=A0A1R0KJ53_9PSEU +----RADFEQLERAFGARLGLYAVDTATGREV-AFRADERFAYASTHKAFSAGGVLQRTP +--IADLGRTVTYRAQDLVSNSPVTEKHVDTGMPLRDVIDATLRYSDNTGGNLLFRELGGP +AGLGAVLRGIGDTTSHVDRIEPELNDTAPGDIRDTSTPRALAVSLRAFALGNALPEDKRK +ILVDIMRANTTGDTNIRAGVP-GWPVADKTGTASYGTRNDIGVIWPPNRAPIVLSVLTDR +ATKDAGIDNKLLAQATAVAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Mycobacterium TaxID=2642494 RepID=UPI00099456AD +-----SEIASLEKDFGGRIGVYALDTGSGATL-GHRPNERFLMCSTVKTFIVSAILHRSL +SEPGLLDKRIHYTQSDIMEWAPVASQHLAEGMTVSELCDATIRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEEELN--VPDGDLDTSSPLQLVTNLRRLVLDEGLDSQGRD +LLTDWLKRNTTGDQSIRAGVPAGWTVADKTGSGFKGETNDIAVIWPPGRAPIVVAVLTVP +DDPKSTQGKPTIAAATRIALKAf +>[subseq from] class A beta-lactamase n=1 Tax=Kosakonia radicincitans TaxID=283686 RepID=UPI0005C31B16 +--RLAEAVRLQEQQLGARIGVAVVDTASGETA-SYRGDERFPLNSTHKALLCGALLSQVD +KGELALTDTTQFPRSALVAYSPVTEKFVAPAISWQQLCSAAVSYSDNTAANLLAQKLGGP +LSITRYLQTLGDSVTQMDRFEPELNSAIPGDLRDTTTPLAVSHTLQKLTLGTALQPGSRA +QLIQWMRDDKVADTLLRSTLPDGWSIADKTGAGDFGSRSIISVVWPQNSSPRIVVIYITN +TKATLKQSNAAIASLGKTIF--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI000A3A6AAA +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYATD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. CC22-02 TaxID=1378087 RepID=A0A4R7UL05_9GAMM +-----ADFAALEKASGGRLGVTVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP +PALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHAGPAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075965CC +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SEV3_9BACT +---LTREVAQEESTLQARIGVAVIDTGSGLIW-QHRGEERFPLNSTHKAFACAAVLAQAD +NNKVSMDMPIPINRDALVTYSPVTGKVPSGGQSLRELCRAAVSVSDNTAANLALNAIGGP +PSFTTFMRSMGDNETHLDRLEPELNEANPGDARDSTTPLAAARSLQKLLLGDVLSTTART +ELTQWMLDDQVADTLLRAGIPKDWRIADKSGAGGHGSRSIIAVIWPPERSAVVIAIYITQ +TTASMSASNQAVSRIGSALAK-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium brachiatum TaxID=269660 RepID=A0A3G2VBU0_9RHIZ +-eAVESALAAIEKRLGGRLGVSAGT-PERVFL-RHRADELFPMCSTFKVLAAACVLARVD +AGTESLDRLVTYGNDVLLSYAPVIRKGLEAGMTVADLCAAALEWSDNSAANLLLAALGGP +EALTLWLRGIGDTVTRLDRNEPTLNTALQGDPRDTTSPEAMRATLARLLLGPSLSAAARA +RLEAWMVASQTGFKRLRAGLPPDWTVGDKTGTGDNGTVNDVAILRPPGRAPILACVYVTG +AQAPTEVVEAAHAEIGRLVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0S1LJ16_ECOLX +--------------------------------------ERFPMMSTFKVVLCGAVLARVD +AGDEQLQRKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAAL---- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0002F6793C +-----NELTSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRRQ +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSGGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP +EDPTSTKGKPTIAAAARIALRAf +>[subseq from] Beta-lactamase (Penicillinase) n=1 Tax=Mycobacteroides abscessus subsp. bolletii TaxID=319705 RepID=A0A1N1AIR0_9MYCO +-----NELTSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRRQ +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSGGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP +EDPTSTKGKPTIAAAARIALRAf +>[subseq from] class A beta-lactamase n=1 Tax=Niveispirillum sp. SYP-B3756 TaxID=2662178 RepID=UPI001291A19B +---MRKDIEALERARGGRLGVAVLDTASGRAM-DWRGDERFAMCSTFKFLLAGHVLALVD +AGRERLDRTLPVPPKKLLDWSPATEPHAGGSLDIAALCHGIITRSDNTGANMLLDATGGP +EALTAWLRQLGDTITRCDRPEPAANLVPPGEVRDTTTPISMLGLMRTLLLGNALSAPSRK +QLTDWLIANTTGDNRLRAGLPAGWKVGDKTGSWDD-ATNDIAIVWPKGAAPLLITSYYRN +ADLDSKGRNAVLAEVGRIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0002DD26FC +-----NELTSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRRQ +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSGGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP +EDPTSTKGKPTIAAAARIALRAf +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0005E7A73C +-----NELTSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRRQ +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSGGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP +EDPTSTKGKPTIAAAARIALRAf +>[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora sp. 7K502 TaxID=2530387 RepID=A0A4R4YFB8_9PSEU +-------FADLERRYDARLGLFAVNVHTGRSM-GYRADERFAMCSTFKTYAAGALLHRHG +LAGGYFDKLIHYTEADLVAGSPVTAPNAGIGLMVNELCAAAITRSDNTAGNLLLAELGGP +SAITAFARSIGDGSTRLDRWETELNTAIPGDERDTTTPAGIAAGYRALVVGDALGAPERD +RLAGWLFANTTGAARIRAGLPPAWRTGDKTGTGDYASGNDVAVTWTDRGQAIVIAVLTTR +PRKDDEVDNGLHADTARVVAA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella sp. 120-Carrot TaxID=678949 RepID=D7PIH1_9GAMM +-----------------------------SQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP +QKVTEYARKLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PQKDAK----------------- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F2D1D +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075A92B8 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVAEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Erwinia mediterraneensis TaxID=2161819 RepID=UPI001031A895 +-------VLQEEKALKARIGVAVMDTASGQTL-SYRGHERFPLNSTHKPLLCGLLLSKVD +AGELSLTDSIRFKKETLVDYSPVTEKFVAPRMNWQEVCQAAVAYSDNTAANLIAKSVGGP +PAVNHFLAAIGDNITRSDRFEPELNTSQPGDLRDTTTPVAISQTLYALTLGKVLQPASRQ +QLLQWMFDDKVADALLRSVLPPHWKIADKSGAGAYGSRSIISVVWPEKREPLIVVVYITQ +TEATMAQSNAAIARIGKTIF--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. BO TaxID=1476855 RepID=UPI000BA4AC23 +-----AVFSVLEDHYDARLGVYALDTGNGQTI-AYNEDERFAYASTHKALTVGVLLQQLS +--LDELDTQILFSEADLVTYSPITEQHVETGMSLHEISDASIRYSDNTAANLIFNEIGGP +SGFKEALREIGDEVTEPERMETELNDVKPGETRDTSTAKALAESLYAFSLGDALDEEKQT +LLNDWLIHNTTGDALIRSGVPEGWLVGDKTGSASYGTRNDIGIIWPPDEDPIVIAVLSSK +EQADAESDDALIAEATEAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754C9B4 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio harveyi (strain 1DA3) TaxID=673519 RepID=D0X6B6_VIBH1 +--KLNEDLASIEEHISGRLGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD +SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNTMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus miscanthi TaxID=2598861 RepID=UPI0011A0444B +----AATFSVLEDHYDARLGVYAFDTGNGQTI-AYNEDERFAYASTHKALAVGVLLQQLS +--LDELDTQILFSEADLVTYSPITEQHVETGMSLHEISDASIRYSDNTAANLIFNEIGGP +SGFKEALREIGDEATEPERMETELNDVKPGETRDTSTAKALAESLYAFSLGDALDEEKQT +LLNDWLIHNTTGDALIRSGVPEGWLVGDKTGSASYGTRNDIGIIWPPDEDPIVIAVLSSK +EQADAESDDALIAEATEAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075261EC +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHDSGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAVPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces koyangensis TaxID=188770 RepID=A0A385DC27_9ACTN +--DAERRLARLERESGIRLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RDGEFLSRRIFYTQDDVERGAPETGKNLANGMTVEELCKVSITASDNCAANLTLRELGGP +NAVTRFVRSLGDRVTRLDRFEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR +LLTSWLLANTTSGDRFRAGVPEDWVLGDKTGAGHYGTNNDAGVTWPPGRPPIVLTVLSTQ +TEQDAVRDDGLVADAARVLAE-- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI0003A2BA26 +--KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD +NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTTFLRSIGDKATRLDRFEPRLNEANPDDKRDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces rochei TaxID=1928 RepID=A0A510DF97_STRRO +------ALADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMDKVIHYPPHDLLPNSPRTEGNQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP +AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALTAPDRE +RFVTWLKGNTTSGARFRAGLPGGWTIADKTGTGDYASANDIGVAWTTRRTPVVLAVLSTK +EGKDAPVDEALIAEAARIAAR-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0010E7CFA1 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSNSLMRSVLPKGWSIADRSGAGNYGSHGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. SC-N050 TaxID=1896671 RepID=UPI0008B386D8 +-----ADFAELEKASGGRLGVTVLDSRTGRRIgGHRQGERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVAVAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVTGGP +AALTAFLRDHGDRVTRNDRYEPDMNRFAAGDPRDTTSPAAMAASLALFAVGDGISAASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG +ASVDEEQRAAVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces lasaliensis TaxID=324833 RepID=A0A4U5WBE4_STRLS +--DLSEEFRALEQSYGARLGVYARNVRTGRTV-AHRAGERFAMCSTFKAFAAAAVLRDHG +-HCAPLDRVIHYPPRDILDNSQHSEDHLATGLTVGQACAAAIQYSDNTAGNLLLRQIGGP +QGLTRFFRSLGDRVSRLDRWETDLNTAVPGDLQDTSTPQALGTSFERLTLGRALARTDRE +QLVTWLKGNTTSAQRFGAGLPQDWTLADKTGTGSYATAHDIGIAWTTRRTPLLLTVLSTK +DAGDAPVDNGLIRDAAALLA--- +>[subseq from] Beta-lactamase n=2 Tax=Tatumella ptyseos TaxID=82987 RepID=A0A085JH61_9GAMM +------QAKLAEQQLHARAGFAELDLATGALReSYRSGERFPMMSTYKVLLCGAVLARID +SGREQPERRIMYRQQDLEKYSPVTKQHLNEGMTIAGLCDAAITMSDNTAANLLLSSIGGP +QALTRFLRQTGDPMTRLDRQEPELNEALPGDPRDTTTPEAMARTLRNLLSGKILTAASQQ +QLLHWMIADQVAGPLLRKVLPAGWFIADKSGAGEHGSRGIIAVTGPAGKPSHIVVIYITD +NDASMDVLNRQIAGIGAAMF--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ru71 TaxID=2080746 RepID=A0A2S4Z4V9_9ACTN +--DLDAELGRLEQRYGARLGVYARNVRTRRTV-AYRAGEPFAMCSTFKAFAAAAVLRDHG +-DCAPLDKVIHYPPRDILSNSQHSEDHLATGMTVGEACAAAIQYSDNTAGNLLLRQVGGP +QGLTRFFRSLGDKVSRLDRWETDLNAAVPGDPQDTSTPEALGKSFERLTLGRALARPDRE +RLVTWLKGNTTSAERFGAGLPRDWVLADKTGTGSYATANDIGVAWTTRQTPLLLTVLSTK +DAKDAPVDNRLIRDAAAVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis coloradensis TaxID=76021 RepID=UPI0009FEB160 +----RADFEQLERAFGARLGLYAVDTATGREV-AFRADERFAYASTHKAFSAGGVLQRTP +--IADLGRTVTYRAQDLVSNSPVTEKHVDTGMPLRDVIDATLRYSDNTGGNLLFRELGGP +AGLGAVLRGIGDTTSHVDRIEPELNDTAPGDIRDTSTPRALAVSLRAFALGNALPEDKRK +ILVDIMRANTTGDTNIRAGVP-GWPVADKTGTASYGTRNDIGVIWPPNRAPIVLSVLTDR +ATKDAGIDNKLLAQATAVAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DDFCEC +--DLADRFAELERRYDARLGGYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP +--LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase class A n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A1H5MF16_9ACTN +-dELSRRLTDLEQQHSARLGVFAHNPATGRSV-LHRADERFPMCSLFKTLAAAAVLRDLD +HHGEFLAKRIRYTAKDVRKYAPVTGTNLARGMTVADLCAAAISYSDNAAGNLLLRELGGP +TTITRFCRSTGDRTTRLDRCEPELNSAEPSRITDTTSPRAIGQTYARLTLGTALTPKDRK +QLTSWLRATTTSGEKFRAGLPSDWAVADKTAGGKYGSNHDVGLAWPPGRSPIVMAVLTTK +REPDAAADNPLVAKTAALLAK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9143 TaxID=2184574 RepID=A0A3N8AAE2_9BURK +--AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAELCAAMLQSGDKGAGNLLMGVLGGP +QTVTSFAHESGDTAFRLDRWEPELNQAAPGDERDTSTPVAMVDTVQRLLLGDTLREPQRA +QLTEWMTGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAAREDVVASAARIATSAf +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas chelatiphaga TaxID=517011 RepID=A0A0R0DGS9_9GAMM +---TAADFAALEKASGGRLGVTLLDTRTGKRT-GHRQDERFPMCSTIKWMIAAAALHRAE +GQPGFLDERLPMRSEDLIEHAPTTRRHVGKDLSVRDLCRTTMVTSDNPAANLLLRRLGGP +PALTAFMRSHDDAVTRSDRYEPELNRFIPGDPRDTTSPAASAASLQRFVLGDALQPASRQ +QLADWLIDNETGDATLRAGLGTRWRVGDKTGSNGKDTRNDIGVLWPLGGSAWVLTAYLQG +ASVDSGQRDAVLARVAAL----- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI000CF3DFCA +--KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD +DEKLDKNATAKVEKRNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNSMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000B8034CF +-dELSRRLTDLEQQHSARLGVFAHNPATGRSV-LHRADERFPMCSLFKTLAAAAVLRDLD +HHGEFLAKRIRYTAKDVRKYAPVTGTNLARGMTVADLCAAAISYSDNAAGNLLLRELGGP +TTITRFCRSTGDRTTRLDRCEPELNSAEPSRITDTTSPRAIGQTYARLTLGTALTPKDRK +QLTSWLRATTTSGEKFRAGLPSDWAVADKTAGGKYGSNHDVGLAWPPGRSPIVMAVLTTK +REPDAAADNPLVAKTAALLAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Alcanivorax sp. 24 TaxID=2545266 RepID=UPI00105B5F7E +---LSRRCQEWEHRHGGRVGVAVWNLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD +RGEESLDRRLLVSREDLVGWSPVTGKRTGEGMTVAELCEAAVAWSDNGAANLLIKSFGGP +GALTDFLRESGDPVTRLDRLEPELNGYGPDGEYDTTSPAAMLETLHRLLFGEVLSAHGRA +QLAAWMIANKTGDRRLRAGFPDGWLVADKTGTSGLGYGNDIGVAWSRDRGAILVTVYCEM +PKAEAGARDRIIAEVAEMVS--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-475 TaxID=1463910 RepID=UPI00068AD3E1 +-----PRLADLEREYGARVGVYALATGTGATV-VHRAGERFAFCSTFKALAAAAVLHHRS +--AGGLDRRVTYTEADLRSTAPVTGKHVATGMTLRELCDAAVRFSDGTAANLLMRDIGGP +GALTAYLRGLGDTTSRMDHYEPELHDVPPDDPADTTTPRAIATDFRTLLLGTALPVRERR +LLMGWLSRNATGARRIRAGLPGDWKVADKTGTGDYGRANDIAVVHPPRSAPLVLAVMTDR +PGRDAEPSDALIAEATRRTV--- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax carolinensis TaxID=553814 RepID=A0A240UCM9_9BURK +--KWSDTLAGIERAAQGRLGVALLDTGSGLAL-GWRQDERFAMASTFKLLLAGWMLALVD +QVRERLDTRVHYAAADVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP +AGFTAFVQSLGDGITRLDRTEPTLNEAALGDPRDTTTPLAMLQTMQKLVLGDALTTLSRA +WLQRWLVETRTGDQRLRAGVP-GWTVGDKTGTADSGTANDVAVLWPPGGAPVLVTCYLTR +SAAKPAQRDAAIVQVARAVAT-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007549A46 +--AAQSQLDALERASNSRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Alcanivorax sp. 6-D-6 TaxID=1177156 RepID=UPI00135B6571 +---LSRRCQEWEHRHGGRVGVAVWNLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD +RGEESLDRRLLVSREDLVGWSPVTGKRTGEGMTVAELCEAAVAWSDNGAANLLIKSFGGP +GALTDFLRESGDPVTRLDRLEPELNGYGPDGEYDTTSPAAMLETLHRLLFGEVLSAHGRA +QLAAWMIANKTGDRRLRAGFPDGWLVADKTGTSGLGYGNDIGVAWSRDRGAILVTVYCEM +PKAEAGARDRIIAEVAEMVS--- +>[subseq from] class A beta-lactamase n=1 Tax=Saccharopolyspora dendranthemae TaxID=1181886 RepID=UPI0011A36B1F +-------LVELERRYDARLGLFARNTATGRTL-AHRADERVAMCSTFKVYASAALLRAHG +LAGGYFERVLRYDAGQLVENSPVTETRVGVGMTIGELCAAALQHSDNTAANLLLRELGGP +RGITDFARAIGDPVTRLDRWEVELNSAIPGDERDTSTPRALADGLQELLLGDVLGAPERE +RLTGWMLGNTTGDTRIRAGVPREWRTADKTGGGSYGVANDIGVTWTGTGTPIVISLLTGR +PGEHDEADSALLADAARLIA--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured Stenotrophomonas sp. TaxID=165438 RepID=A0A1Y5Q422_9GAMM +--AAAANFAALEKHSGGRLGVCLWHPASGARF-GHRMEERFPMCSTFKFPLVAAVLHRAG +HGGLSLDQRVPVRQADILHHSPVSGRHVGKDMSVRDLCRATLTVSDNAAANLLLPLVGAP +AGLTAFLRGQGDAVTVAARREPELNSFAPGDPRDTTSPAAMAGNLQRFVLGDALGEIPRR +QLADWLIDNETGDERLRAGLPQGWRVGDKTGSGYDGISNDIAVLWPPAGTPWLLAAYLQG +ATQDASGRNGILRRAAELAAAH- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=V5RLB4_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVACL---------------- +----------------------- +>[subseq from] TEM-169 beta-lactamase n=1 Tax=mixed culture bacterium PI_gF3SD01_11 TaxID=663181 RepID=C8C179_9BACT +------------------------------------------MMSTFKVLLCGAVLSRVD +PGQEQLGRRIHYSHNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase FRI-5 n=1 Tax=Enterobacter cloacae complex sp. TaxID=2027919 RepID=A0A2S0RJ30_9ENTR +-----AKMKELETAFGGRIGVYLLNTGNGKEF-SYRQDERFPLCSSFKVFLAASVLKRIQ +SKSISLDDSVEYVGRVMEKHSPVSEKYREKGASVQTLAMAAIQYSDNGASNLLMERIGGP +EGLTAFMRSTGDTDFRLDRWELELNSAIPGDKRDTSTPKAVAMSLKNIAFGSILNAKNKA +LLQDWLKGNTTGNARVRAAVPDKWVVGDKTGTCGYGTANDVAILWPDNNSPAVIAVYTTR +PNQNDKHDETVIKNAAKIAID-- +>[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium sp. lm94 TaxID=2678685 RepID=UPI0012EED906 +-dRLAETIHRVEDRLDARTGVMVRDTGSDWTW-AYRAEERFLMNSTVKPVICGAVLAEVD +GGALTLDEVLPIRDENLLSYAPVTETRVGESMSIGDLCLATLDMSDNTAANLLMDRLGGP +QEVTAFLRDIGDPVTRLDRREPELNTFAPGDPRDTTTPAAMLDTLQAMLLGDALTPASRA +QLAEWMSRGGVTGALLRAEAPADWEIADKSGGGDQ-TRNIVAMVTPRDHAPWLVAIYLSD +ADVDFVTRNAALQEIGAAVM--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodovibrio salinarum TaxID=1087 RepID=UPI0004B62451 +--KLADTVAQIEQSLDARVGVAVVDTGSGEAW-THRPDERFLMNSTAKVPICGAILAQAD +DGELALSETLPVHESDLLSYAPVTSEHVGDRMSLTQLCLAALDMSDNTASNLLLDRLGGP +EVVTELFRNADDPVSRLDRREPEMNSFAKGDPRDTTTPIAMAETMRALLLGDVLTPASRE +QLAEWMSHGAVTQELLRSHAPDGWVIADKSGSGSQ-TRNIIALISPPNAAPWIVTIFISD +AKADFATRNAALKEVSAAVM--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. RIT309 TaxID=1470590 RepID=UPI000450CD48 +---AAADFAALEKACSGRLGVTLLDSAGSRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDAALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA +GTISFEQRAAVLAQVGRIA---- +>[subseq from] Uncharacterized protein n=1 Tax=Pseudolabrys sp. Root1462 TaxID=1736466 RepID=A0A0Q7TPM6_9RHIZ +-----KRIADLETKLGGRLGVYVSD-ATGRVLiAHRDTERFPMCSTFKFLLGAAALKRAE +QGSITLDQVLPFGEADLLSYAPVTKANVGKGMSVHDLCAAAVTLSDNTAANLVMRAIGGP +AAVTAFARSIGDHDTQLDRFEPELNSAIPGDPRDTTTPRAIAEDLRRILAGNALAPTSVQ +MLEGWMTDSKTGLKRLRAGLPHDWSTADKTGSGANATANVVALVRPKSRPTLFVATYITG +ATLDGDALDAGHADVGRIISD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007527F02 +---AQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia spinosispora TaxID=103441 RepID=UPI0003F97BD6 +---MAGRFQDLERRHGARLGVYGQNTRTGETV-AYRGGERFALCSVLKGLLAAHVLRDHD +RAGEFLARVIPYTRAELTAASPVTENFVGAGMAVRDLCAAAIIYSDNAACNLLLRETGGP +PALTTFMRSIGDEHTRLDRIEPDMSSSIPGDLRDTTTPEAIGRSYQRLVLGDALDPGDRD +LLTMWLKTTATSGKRFRAGLPTDWVIGDKTGTGDYGTANDIGIVWTSKGTPLVLSVMTTH +DAKDTAIDENLIVEATRLL---- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. JCM 19052 TaxID=1460647 RepID=A0A061Q3B1_9VIBR +--KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD +SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +HGVTRFLRSIGDKATRLDRFEPRLNEAKPSDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] Beta-lactamase n=1 Tax=Nocardia ninae NBRC 108245 TaxID=1210091 RepID=A0A511ME19_9NOCA +-----PRFVELEQQFGARLGIYALSTGTNRTL-THRADERFAFCSTFKALAAAAVLHHNP +--LTHLDKPVTVTKADIRSISPVTEKRVDTAMTIGELCDAAVRFSDGTAGNLLLDDIGGP +AGLTGYLRGLGDPVSRMDQYEPELNRDPPGDDRDTTTPRAIAADYQQLILGSALPEDKRA +ILTDWLVRNMTGAKRIAAAAPAGWTIADKTGTGDYGRANDIAIVWPTSHPPLVLAIMSDR +TGYDAEPSSELIAEAARHIF--- +>[subseq from] Class A beta-lactamase n=1 Tax=Saccharopolyspora sp. 16K404 TaxID=2530385 RepID=A0A4R4UNB5_9PSEU +--------AELERRYDARLGLFARNVATGRTV-AHRADERVALCSTFKVYASAALLRAHG +LAGGYFDRVIRYDAGQLVENSPITETRVHTGMTVGELCAAAVQHSDNTAANLMLRELGGP +QAITEFARTIGDPMTRLDRWETELNTAIPGDERDTSTPRALGDGLQRLLLGDALGPAERD +RLTGWMLGSATGAARIRAGVPSSWRTADKTGGGSYGVANDIAVTWTDTATPIVISLLTGR +PREHDTANNALLADAARVVAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Mesorhizobium sp. TaxID=1871066 RepID=A0A527TNI5_9RHIZ +---AEARLADLERKHRGRVCVSILDLASGTRI-GHRTSERILMCSTFKAMAAAFVLARVD +KGKEKLGRRIKFTKKELVEGSPATEMHVGGPMTVAELCDAAVTRSDNTAGNLLLTSFGGP +AGLTAFFRSLGDDISRLDRIETELNYDGPDDVRDTTTADAMLENLRKLLFTDILSGPSRS +QFAAWLINNKTGDTRLRAGLPKNWLVGDKTGTNGYGNANDIAVIWPSDRGPIIVTAYCEM +PSIAADERNAIIAEIGQFAA--- +>[subseq from] Beta-lactamase n=5 Tax=Streptomyces TaxID=1883 RepID=A0A380MQH4_STRGR +---AVRRLAGLERASGARLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RDGEFLSRRIFYTAKDVERGAPETGKNLANGMTVEELCEVSITASDNCAANLVLRELGGP +TAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITGTYGRLVLGDALNPRDRR +LLTGWLLANTTSGGRFRAGLPKEWTLGDKTGAGRHGTNNDAGVTWPPGRSPIVLTVLTTQ +PEEDAVRDDGLVADAARVLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000755CE4D +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHDSGDTLFRLDRWEPELNTARPDDERDTSTPLTMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGIKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Microbispora sp. KK1-11 TaxID=2053005 RepID=A0A544ZFL1_9ACTN +--DVAAALRALETSFKGRIGAYAIDTATGKTI-GYRAGERFPLLSTFKAVAAAAVLARTT +-DRELTRKVVHWTADEVKDYSPETSKHVEDGMTLAELARAAITYSDNTAGNMLLKRIGGP +EGLTRYFRTLKDPISRLDRWETELNDWSPKDRRDTTTPASAARDLRTLTTGDVLGAKDRS +RLIGWLRGNTTGDARIRDGLPKTWIVGDKTGTGSYGPANDIAVVWPRKGAPIIMAIYTNR +LAADGAADNKVIARTATVLA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Salipaludibacillus neizhouensis TaxID=885475 RepID=A0A3A9KJ30_9BACI +---TNYSFEELEKEYDAKLGVYALNTGSNQSV-SYREDERFGYASAHKALAVGVLLKNKS +--IEELDEKINFTEEDLVNYNPVTEEFVDEGMTLKELSDASMRYSDNTAANLILEAIGGP +EGFKEVLREIGDDVTEPERIEPDLNDVSPGETNDTSTPKALAESLQSFTLGDVLSEEKQE +MLNDWLIRNTTGDNLIRAGVPEDWVVGDRTGSGSYGTRNNIAVIWPPNDDPIILSILSSR +EEPDADYDDELIAKAAEIAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora dendranthemae TaxID=1181886 RepID=A0A561U6V6_9PSEU +-------LVELERRYDARLGLFARNTATGRTL-AHRADERVAMCSTFKVYASAALLRAHG +LAGGYFERVLRYDAGQLVENSPVTETRVGVGMTIGELCAAALQHSDNTAANLLLRELGGP +RGITDFARAIGDPVTRLDRWEVELNSAIPGDERDTSTPRALADGLQELLLGDVLGAPERE +RLTGWMLGNTTGDTRIRAGVPREWRTADKTGGGSYGVANDIGVTWTGTGTPIVISLLTGR +PGEHDEADSALLADAARLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Aeromicrobium sp. M2KJ-4 TaxID=2292704 RepID=A0A371P2N1_9ACTN +---ADAELAALEASSNARVGVYVRDTVTGRTV-AWRSGERFPFASTIKAPLAGAVLERVS +--HADLSRVVRFDRADLVPHSPVTEQHVDDGMPLRDVLDAALRFSDNTAANLLFDEIGGP +AGLDRALERLGDRLTDPRRIEPDLNTAVPGEVRDTTTPRALATTVGAYLLGDALPKDDRE +LLRTLMVTSTTGDGLIRAGVPDGWVVADKSGGAAYGVRNDVAIAYPPGRGPVLIAVMTRR +GQADDAYDDAAVAGATRIAVA-- +>[subseq from] Beta-lactamase n=2 Tax=Curtobacterium oceanosedimentum TaxID=465820 RepID=A0A147DR87_9MICO +--ATSRAFAALEEQYGARVGVVAIDTADGGSL-GYRADERFAFASTNKAFIAAAVLARSN +--TDDLDDVVRYDRSDLLSHAPVTSQHVDEGMTVRALVDAALRESDNTAANLLVERLGGV +GGVSRWLRGIGDDVTRVDRVEPDLNTAVPGDPRDTTTPAQSASDLRAVLLGDALDPDDRA +LLRSATAGTTTGDGTIRAGVPDGWSVADKTGTASYGVRNDIAVVQPPGRDPIVLVVFTTR +DGADAEPSDALVAAATRVAVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0004B80A33 +----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT +--DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP +ERFEKELKGIGDKVTDAARYETALNKATPGDRRDTSTARALTEDLREYAVDDALEPADRD +ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR +DEQDASYDT-------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5123 TaxID=1463856 RepID=UPI0004E159D0 +----DAVFRAIEDRYGARVGLFLLDTGTGRTV-TYRPDRRFAACSTVKVLAAAALLRQEE +---TDLDRTLTYTRADVLAHAPVTSRHVAAGMALRDVMDAALRYSDNTAENLLLRELGGP +AGLQRAVRGLGDATTRTDRTEPSLNEAAPGDIRDTSTARALAADLRVLLVGNALPADRRA +LLTDWMTRNTTGGPYIRAALPAGWTAADKTGSGGYGTRNDIAVLRPPAAAPLVIAVLTSR +DHADTSSADALIADTTRAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. SPM TaxID=2170735 RepID=A0A363RY79_9GAMM +----AADFAALEKASGGRLGVTVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVSGGP +PALTAFLRTQGDTVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGDGLSEKARL +QLADWLIDNQTGDACLRAGVGKRWRVGDKTGSNGEDTRNDIAVLWARGGTPWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075413E6 +--AAQAQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLIGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria (strain MC40-6) TaxID=398577 RepID=UPI000776AD73 +hhHHHAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP +QAVTSFAHESGDTVFRLDRWEPELNLAAPGDERDTSTPVAMVDLLQQLLLGDTLREPQRA +QLTEWMTGGARGATAIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIAT--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075BD064 +--AAQAQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Frondihabitans sp. PAMC 28766 TaxID=1795630 RepID=A0A126Z4G5_9MICO +--RTAAAFRALESRYGADLGVHAVDTRTGRTV-DFDADRRFAFASTYKALAAGVLLRRDT +--GAQLSQTIHYTAADLVDYSPITEQHLSTGMSLGDIIAAALQYSDNTAANLMLEQLGGP +QGLQSALRGLGDTTTNVDRTEPDVNTATPGDPRDTTTAAAIGTDLRAFVLGAALTPARRE +RLAALMRGNTTGGPYIRAGVPADWTVGDKTGNGGWGTRNDVGVAWLPDGDTVVVSILSDR +HTSGASSDDALLADATKAVV--- +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=Q8RNV0_CITKO +---------QEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD +RKALALSASMQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP +QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE +QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ +TPATMAQRDAAIVRIGESLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. CY41 TaxID=2608686 RepID=UPI0013571B46 +----HDRLIELEGKFDARLGVYARATGTGATI-AHRADERFAFCSTFKGLAAAAVLQRNP +--LSHLDTVVTYTRDDLLKNASVTPRHLDTGMTIRQLCDAAIRYSDGTAGNLLLRDLGGP +AELTAYARSLGDTVTRMDRIEPAITEATPGDPRDTTSPRAFGELYHRIVVGDALPPDKRD +FLRDLMERNATGAQRIRAGTPQGWTVADKTGTGDYGTLNDIAIVWPLASPPLVVAVMSSK +AARDASYDQGLLAEAAAYVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. PhB136 TaxID=2485181 RepID=A0A4R1KJ44_9MICO +--SADASFRRLEQQHDARLGVVAVDTGSGHRV-EYRQGERFAFASTNKTFIAAAVLAGAS +--DTDLETVVHYDRSDLLDYAPITSRFVDTGMTVRELIDASLRFSDNTAANLLVERLGGP +DAVERYLRGIGDRVTNVDRVEPELNEATPGDARDTTTPAQFATDLRKVVLGTTLEPTDRT +FLRDTMLDNTTGAGTVRAGVDPAWPVADKTGTGEYGVRNDIAVVYPSGRAPLVVVVMTSG +KQSDATADDALVAAATKAAVA-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas indicatrix TaxID=2045451 RepID=UPI0013D8E9E1 +---AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQEERFPLCSTFKSVLAATVLKQAE +RDPALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWILTAYLQA +GAISFEQRAAVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. ZW137 TaxID=2485104 RepID=A0A3N1J0J3_9MICO +--SADASFRRLEQQHDARLGVVAVDTGSGHRV-EYRQGERFAFASTNKTFIAAAVLAGAS +--DTDLETVVHYDRSDLLDYAPITSRFVDTGMTVRELIDASLRFSDNTAANLLVERLGGP +DAVERYLRGIGDRVTNVDRVEPELNEATPGDARDTTTPAQFATDLRKVVLGTTLEPTDRT +FLRDTMLDNTTGAGTVRAGVDPAWPVADKTGTGEYGVRNDIAVVYPSGRAPLVVVVMTSG +KQSDATADDALVAAATKAAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0005DE1547 +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGSAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides salmoniphilum TaxID=404941 RepID=UPI000992E853 +-----TELAALERDFGGRVGVYALDTGSGATL-SHRANERFLMCSTVKTFIVSAILHRRL +SEPGLLDKQIQYTQSDVLEWAPVTSQHVAEGMTVSELCDATIRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDSQGRD +LLTDWLKRNTTGDQSIRAGVPAGWTVCDKTGSGFKGETNDIAVIWPPGRAPIVVAVLTVP +DDPKSTKGKPTIAAATRIALKAf +>[subseq from] Beta-lactamase n=1 Tax=Arsenophonus endosymbiont of Trialeurodes vaporariorum TaxID=235567 RepID=A0A3B0LZ15_9GAMM +--------SKKKKKLNSRIGVAVIDTANNVTV-SYRGNKRFPLNSTFKALLCGMLLNQVG +NGKIVLTESVQFEKGQLVAHSPVTEKFIAPLMNWQQLCAAAISYSDNTAANLIEKKVGKP +TSFTRFLRSIGDRVTRLDRFEPELNSAIPGDKRDTTTPVAISQTLQKLVLGDVLQPSSRQ +QLRQWMEDDKVANALLRSVLPAQWKIADKTGTGDYGSRSIISLVWPEKRQPLIVSVYITQ +TKATLAQSNEAIARIGKAIFS-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE7661 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGQTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007589D1E +---AQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000753AC05 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTDWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria (strain MC40-6) TaxID=398577 RepID=B1YX81_BURA4 +--AAQAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP +QAVTSFAHESGDTVFRLDRWEPELNLAAPGDERDTSTPVAMVDLLQQLLLGDTLREPQRA +QLTEWMTGGARGATAIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIAT--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseofuscus TaxID=146922 RepID=UPI00055A3FC8 +------AFADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMEKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP +AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALAAPDRE +RFVTWLKGNTTSGARFRAGLPGGWTIADKTGTGDYASANDIGVAWTTRRTPVVLAVLSTK +EGKDAPVDEALIAEAARIAAR-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. TaxID=1785 RepID=A0A3S0TED9_9MYCO +--DLSGQFADIERRYGGRLGVYVPESGTTAAI-AYRADERFALCSTFKAPLVAAVLHQYP +--LAHLDSMVSFTKADINSISPVTEQHVDTGMTVGQLCDAAIRYSDGTAANLLLTQVGGP +AGFTDYLRSLGDDTSRLDQAEPELNRDPPNDARDTTTPHAIALVFQKLVLGDALPPDKRT +MLTDWMARNTTGGKRIRAAFAADWKVIDKTGSGDYGRANDVAVVWSPKGVAHVIAIYTDI +AGYDAQPNEAFVADAARVVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI000578884E +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSNGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPASTKGKPTIAAATRIVLRAf +>[subseq from] Beta-lactamase n=2 Tax=Frondihabitans sp. PhB188 TaxID=2485200 RepID=A0A3N1QCP5_9MICO +------PFRALESRYSARLGVYAVDTGTGRTV-EYRSGERFTFASTYKALAAGVLLKTQT +--DAELDAVVRYSASDLVDYSPVTEKHVASGMTVRAIIAAALQYSDNTAANLLLEQLGGP +ADLTSALRSLGDDVTNVDRTEPDVNTATPGDPRDTTTPAAIAGDLRGFVLGGTLSRTRAQ +ELRDLLLGNTTGAPWIRAGVPAGWRVADKTGNASYGTRNDIAVVYPSTGDPIVLALLSDR +GVEGAASDDDLLADATKAVVEQ- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC201 TaxID=1848320 RepID=A0A4R4MZQ1_9ACTN +--RATKELRALETSFKGRIGAYAIDTANGRTI-AYRSDERFPLLSTFKAMACAAVLHKAR +TQPGLMNKRVRWTARDLVDYSPVTEKHVKDGMTVAGLCHAAITMSDNTAGNLILKQIGGP +AGLTRYFRSLKDRVSRLDRWETELNDWTPKSRRDTTTPSSIARDLRAVTYGKALNAKDRA +RLNAWLIANKTGDARIRAGLPKTWLIGDKTGTNSFGGGNDIAVIWPKKAAPIIMAIYTNR +RP-GLAADDKTIAKTAEVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Leo170 TaxID=1571199 RepID=A0A4Q8QVZ7_9BRAD +-------FEAYERETGGRIGVYAENVATGAKI-TWRSDERFVMCSTFKASLAACVLARID +RGEDGLENVVRYRAADLLHHAPAARQNLSSGMSVADMCKAVVELSDNTCANLLLARIGGP +PALTAFWHETGDTVSRLDHYELELNRSPPGDPHDTTTPAAMAGNLRHFVLGEALSPASRE +RLTDWMLNCKTGNNRLRGGLPKDWKVGDKTGNNGKDAAGDIAVVWPRGGGPVLISAYTQG +GSPTTAQLEAVFAKIGQMVGRQf +>[subseq from] class A beta-lactamase n=1 Tax=Microbispora rosea TaxID=58117 RepID=UPI0004C477F9 +--DVAAALRALEASFQGRIGAYAIDTATGKTI-GYRAGERFALLSTFKAVAAGAVLARTT +-DRELTRKVVHWTAGEVKSNSPETGKHVKDGMTLAELCRAAIIYSDNTAGNMLLKRIGGP +RGLTRYFRTLKDRVSRLDRWETELNEWSPKQKRDTTTPASVARDLRALTTGDALGAKDRS +RLIGWLRDNTTGDARIRAGLPKTWIVGDKTGTGGYGTANDIAVVWPAKGAPIIMAIYTNR +RAADGATADKVVAQTATVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TSRI0281 TaxID=1718998 RepID=A0A1Q4YV90_9ACTN +--RTDRAFAALERKFDARLGVYALDTGNGLFV-THRPDERFAYASTCKALLAAAVLDRNS +--LKELGRRVRIGRDVPVGHSPVTERAVGSELTLRELCDAAVRYSDNGAANLLFRELGGP +RGLQSALVAIGDRVTRCDRYEVALSDAVPGDVRDTSTARALATDLRTYVLDDALPAGKRA +VLTDWLRRNTTGDTTIRAGAPAGWQVGDKTGSGGYGTRNDIAIVWPPDAAPIAIAVLSRR +DTRDAERDDALIAGAAEVALN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides abscessus subsp. abscessus TaxID=1185650 RepID=A0A1N1CVH9_9MYCO +-----DELASLEKDFGGRIGVYALDTGSGGTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] Beta-lactamase n=2 Tax=Kitasatospora sp. OK780 TaxID=1882771 RepID=A0A2N0JIW3_9ACTN +---VTRALADLEHEHSARLGVFARNTVTGAQV-LHRAHELFPVCSVHKVMTAAAVLRDLD +RDGTFLARRLHYTDRDVADYAPITGEHLGAGMTIAELCAAALDHSDNAADNLLLRQLGGP +AAVTRFCRSLGDGVTRLDRWEPALNSAEPERVTDTTTPAAIARTLADLVLGTALAPPDRR +LLTAWLRANTTGAGRLRVGLPAPWTLADKTGTGAYGTTNDVGIAWTTDGTPLVLAVLSTK +PDANAAADEPLIARAAALLV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-24484 TaxID=1463833 RepID=UPI0004C0B348 +-----RALAALEREHGARLGVFARNAVTGAQV-RYRAHELFPICSVHKIVTAAAVLRDLD +RDGEVLARRIRYTAQDVADYAPVTGEHLAAGMTVAELCAAALDHSDNAADNLLLRELGGP +SAITRFCRSVGDRVTRLDRWEPALNSAEPGRVTDTTSPAAIARTLTDLVLGTALAPRDRR +QLTTWMLGNTTGAARLRAGLPSDWALADKTGTGSYGTTNDVGIAWTADRTPVVLSVLSTG +PEPYATADEALIAGTAALLV--- +>[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=UPI000C9CD7FE +--DLAETIRSWETALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD +RGTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP +EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTATPRSVLSTLHAALSGTMLSGSSSA +QLADWMQRDQLADDLIRAHLPEGWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE +TNADFSRRNQAISDIGRAMI--- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Vibrio TaxID=2614977 RepID=A0A2U2IT56_9VIBR +-sQLNEDISLIEQQTSSRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRSIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLIAQISQLILQKy +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2T1I186_STEMA +-----ADFAALEKASGGRLGVTVLNAGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAVWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. HCCB10043 TaxID=1396518 RepID=V6U6S2_9ACTN +--------------------MYAIDTGTGREV-THNDRARFAFNSTFKALQAAVVLSTYS +--LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +RGLDASLERLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR +GTKDAEPEDRLIAEAASVVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 3MP-10 TaxID=2586635 RepID=A0A5N6A678_9ACTN +----AEEFDALEGEFDALLGVYAVDTGTGREV-AHRADERFAYASTFKALLVGAVLDEHG +--ANGLDEVISYTADDLLDNSPVTENFVDAGMSLRELCAAALWYSDNAAANLLLDVVGGP +GALEAWLRQLGDDTTRMDRWEPDLSEGTPGDDRDTSTPRALAADLRALLLGDALGDAERA +LLRQWMETNTTGETLVRAGVPAEWTVADKSGTAGYGGRNNIAVLWPDDGEPIVLAVMSRR +DQQGAERDDALIARAATVAVE-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A6A0BZ91_STRDI +---AVRRLAGLERASGARLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RDGEFLSRRIFYTAKDVERGAPETGKNLANGMTVEELCEVSITASDNCAANLVLRELGGP +TAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITGTYGRLVLGDALNPRDRR +LLTGWLLANTTSGGRFRAGLPKEWTLGDKTGAGRHGTNNDAGVTWPPGRSPIVLTVLTTQ +PEEDAVRDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Microbispora rosea TaxID=58117 RepID=A0A1N7BVU4_9ACTN +--DVAAALRALEASFQGRIGAYAIDTATGKTI-GYRAGERFALLSTFKAVAAGAVLARTT +-DRELTRKVVHWTAGEVKSNSPETGKHVKDGMTLAELCRAAIIYSDNTAGNMLLKRIGGP +RGLTRYFRTLKDPVSRLDRWETELNEWSPKQKRDTTTPASVARDLRALTTGDALGAKDRS +RLIGWLRDNTTGDARIRAGLPKTWIVGDKTGTGGYGTANDIAVVWPAKGAPIIMAIYTNR +RAADGATADKVVAQTATVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. ZAC14D1_NAIMI4_6 TaxID=2072410 RepID=A0A3S7K6V5_9GAMM +-----ADFAALEKVSGGRLGVTVLDTGSGRRIaGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP +PALTAFLRAQGDAVTRNDRYEPEMNRFAKGDPRDTTSPAAMAASLARFAVGNGLSTASRL +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGEDTRNDIAVLWPRGGAPWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. YC504 TaxID=1775132 RepID=UPI0013EA6188 +------EFGALEREYDARLGVYALDTANGREV-AYRADERFAYCSTCKAFLAAAVLDKRG +--VDGIDGEVTVRASDVEGWSPVTGKHIGARMALRSLCDAAVRYSDNGAANVLFRELGGP +RGLQSALRAIGDDVTRCDRYEVELSQAVPGDERDTSTPRAMARSLREFALGDVLADDERA +LLTGWLVRNTTGAKLIRAGAPDGWRIGDKTGNGSYGTRNDIALAWPPSGKPVVLAVMSRR +NGADAPHDDALIARASTAVF--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacteroides salmoniphilum TaxID=404941 RepID=A0A4R8S9N9_9MYCO +------ELASLEKDFGGRIGVYALDTGSGATL-GHRPNERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIHYTQSDIMEWAPVASQHLAEGMTVSELCDATIRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEEQLN--VPDGDLDTSTPLQLVTNLRRLVLDEGLDSQGRD +LLTDWLKRNTTGDQSIRAGVPAGWTVADKTGSGFKGETNDIAVIWPPGRAPIVVAVLTVP +DDPKSTQGKPTIAAATRIALKAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI000754C74F +--AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCMAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA +QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLALSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. TN58 TaxID=234612 RepID=A0A1L7GNH2_9ACTN +----VRRLRALEREYGARVGAYARDTGTGRTV-RYRADELFPMCSVFKAPAAAAVMRDLD +RDGGFLARRIRYTAQDVAGGGSVTGENIAQGLTVAELCSAAIAQSDNCAANLLLRELGGP +SAITRLCRSVGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIARTYGRLVLGDALVPRHRE +LLTRWLVSNTTSGDRFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK +PEAAAPRENALVARAAEVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007525300 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLIGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Jiangella alkaliphila TaxID=419479 RepID=A0A1H2GXA0_9ACTN +--AVAAALAALETDYAARLGVYAVDTGTGETV-EHRPDERFAFASTHKMLSAAAVLQATE +--PADLAEVIAFDAADVVGFSPVTEPAAGTGLTLQQIIEAAITVSDNTAANLLFEQVGGP +DGLEAVVRDFGDEATSFDRIEPDLSDWVPGETRDTTTPRAMAANVEGLLLGDLLAEEDRT +LLHDTMRANTTGDELIRAGVPDGWVVADKTGSASHGGRNDIAVLEPPGAAPIVLAVYSNR +LDPEAESDPALIAAAAAIVVDEf +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio hyugaensis TaxID=1534743 RepID=UPI000CE4A5E8 +--KLNEDLTTIEEHISGRIGVSVWDTQTEEHW-DYRGDERFPMMSTFKTLACATMLKDMD +NEKLDKNATAKVEERSMVVWSPVMDRMVGQSTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTMFLRNIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLQTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRAGTGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075AA3A4 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075A989F +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +AGADASPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009270113 +-----NELTSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRRQ +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSGGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP +EGPTSAKGKPTIAAAARIALRAf +>[subseq from] class A beta-lactamase n=1 Tax=Sporosarcina sp. D27 TaxID=1382305 RepID=UPI0004716AAF +-eTTKEKFEELEKEYDARLGVYAIDTGTKEIV-EFREDERFAYTSTSKALAAGVLLKQNP +--ISELEEIRTFTSEDIVPYSPITEGFVNKGMTLGKIAEAAMQYSDNTAGNLLFKELGGP +DGFEKALRESGDTITMADRIEPDLNEAIPGDSRDTSTPKALATNLEVFGVSEYLSADKQE +IFTNWLKGSTTGDSLIRAGVPEGWEVGDKSGAGGYGTRNDIAIVWPPNREPIMIAIMSSR +DEEDASFNDELIAKATEVIAKAf +>[subseq from] Class A beta-lactamase n=1 Tax=Vibrio antiquarius (strain Ex25) TaxID=150340 RepID=A0A657N643_VIBAE +-sQLNEDISLIEQQTSSRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRSIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGQGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLIAQISQLILQKy +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. TaxID=376 RepID=A0A160UJJ3_BRASZ +--DAQPELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD +RGEDELAAMIPYGNVDLLEYAPVARQNIAAGMSVTEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDATSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLRRLVTGEALSTTSRA +QLTEWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKDTAPILIAAYTQG +GTPSAAQIEIAFARIGRMLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis synnemataformans TaxID=61305 RepID=UPI0003450832 +----ADEFADLEEEFDARLGVYAVDTGSGEEV-AHRSDERFAYCSTHKAFTAALVLQQNT +--PEEMEEAVTYDADDVFGHSPVTGQHVDTGLPLVEVADAAVRHSDNTAANLLFDELGGP +DGFEEAMEEMGDDVIEADRVEPGLSRWTPGDTRDTSTPRAMAGSLREFVLGDALPEDRRE +VLTRMLVDNLTGDELIRAGVPEGWEVGDKTGNGSYGTRNDIAVLWPPEGDPIVLAVMSSR +EAEDAEYDNALVAGAAEVVVE-- +>[subseq from] Beta-lactamase n=2 Tax=Nocardiopsis sp. JB363 TaxID=1434837 RepID=A0A1R3UJ43_9ACTN +--DVSAEFEALEEEFDARLGVYAVDTGSGDVV-AFQEDERFAFASTFKALLAGVVLSENS +--LEEMERVVTFDEGVLVPHSPVVEENLDSGMSLLELCDATVRYSDNAAANILLDEIGGP +EGFTEAVGETGDEVTNLTRYEVELNEATPGEERDTSSARAMAESLEAFTLGDVLPEDRRE +VLVDLLVRNTTGDDLIRAGVPQGWVVGDKTGSGGYGTRNDIGVLWPEEGDPIVLAVLSSR +DAEDAESDDALIAEASEVVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075574FD +--AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA +QLTEWMTGGARNASGIAAGVPPGWRIADKTGIGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. SL1 TaxID=2137478 RepID=A0A327I7P7_9GAMM +--DLERQLGELERSVDDRVGVALLNVATGAVA-SHRGDERFLFNSTGKFFIAAAVLARVD +ESRETLDRRIVIEEGDLVGWTPITEKRLGEPLTVAELCQAAVAWSDNAAANALIESVGGP +EAVTAFLRAIGDDTTRLDRVEPELNTDHAGDERDTTTPLAMMATLRTLLLGDALSPSSRH +QLAAWMIEGKVGDARLRAGMPSSWLVGEKTGTNGEGNANDIGIAWPGDRGAVIAVAYTFM +PDASGAERDETIAAVGRLAA--- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio hyugaensis TaxID=1534743 RepID=UPI0005EEFFF8 +--KLNEDLTAIEEHISGRIGVSVWDTQTEEHW-DYRGDERFPMMSTFKTLACATMLKDMD +NEKLDKNATAKVEERNMVVWSPVMDRMVGQSTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTMFLRNIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLQTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRAGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas sp. X-1 TaxID=2571115 RepID=UPI00110B7768 +-----KDFAALEQVSGGRLGVTLLEVATGRRL-GRRQDERFPMCSTFKALLAAHVLSLAD +AGTLSLDERLPIRQAQLLSWAPESERHVGKDLTVRDLCRAAVTNSDNTAANLLLARAGGP +PALTTFLRRQGDAVTRSDRYEPEMNNFAPGDPRDTTSPAAVAASLARFAVGDGLSKASRA +QYADWLIDNQTGDDCLRAGLGKRWRVGDKTGNNGRDTRNDLAVLWPLGGAPWVLVALLQG +ARVDADQRDAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces viridochromogenes TaxID=1938 RepID=UPI00069DA4B6 +----AGQFRALEREFDARLGVYALDTGTGRSV-GYRADDRFAYASTFKALAAGAVLRKFG +--TDGIDKVVKYSRDDLVENSPVSENFVETGMSLRGLCAATLWYSDNTAVNLLLHELGGP +DGLEKALEDLGDDVTEMDRYEPDMSEGAPGDIRDTSTPRAMAGSLRAFLLGDALKRDERE +LLRQWMTTNMTGRTLITAGVPDGWEVADKSGTAGYGGRNNIAVLWPDDGNPVVMAVMSTR +GKQGAERDDALIAKAATVAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces viridochromogenes TaxID=1938 RepID=A0A0J7YXC9_STRVR +----AGQFRALEREFDARLGVYALDTGTGRSV-GYRADDRFAYASTFKALAAGAVLRKFG +--TDGIDKVVKYSRDDLVENSPVSENFVETGMSLRGLCAATLWYSDNTAVNLLLHELGGP +DGLEKALEDLGDDVTEMDRYEPDMSEGAPGDIRDTSTPRAMAGSLRAFLLGDALKRDERE +LLRQWMTTNMTGRTLITAGVPDGWEVADKSGTAGYGGRNNIAVLWPDDGNPVVMAVMSTR +GKQGAERDDALIAKAATVAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea sp. 160415 TaxID=2495887 RepID=UPI00110C42DD +--QVRKDLRKLEASFKGRIGAYALDTATGRTV-TYRAGERFPMLSTFKAPLCAAALHRAR +AEPGLMDKLVKWTAADLRPNSPVTEKHVKDGLTVAQLCEAAVTVSDNTAANMVLKRIGGP +AGLTKYFRSLKDPISRLDRYEPELNDWTPKEKRDTTTPAAIARDLRLLTTGNALQAKDRE +QFNAWLLASKTGDARIRAGLPKTWTIGDKTGTNSTGGGNDIAVIWPEKGAPIIMAIYTNR +SP-GLATDDKAIAKTATILA--- +>[subseq from] Beta-lactamase Toho-1 n=1 Tax=bacterium YEK0313 TaxID=1522316 RepID=A0A0A1PLU1_9BACT +----GDRLRALETRRGGRLGAAIIDTASGASA-GHRADERFAMCSTVKFLAAAHALARVE +RGEDRLDRRIVVRPGDVVSHSPIAARRLGGPMTLAELCEAAITVSDSTAGNLLVGAAGGP +AGLTGYCRALGDTVTRVDHLAPFAASG-PNDANDTTSPRAMAENVRRLLLGEALRPASRA +QLTAWLVANRTGDERIRAGLPHGWRVGDKTGSGRGGECNDIAIAWPPGRAPLILSFYYVK +AGASAAVRNAVIAEATRLVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=A0A344KNG4_9VIBR +--KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD +DEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTTFLRSIGDKATRLDRFEPRLNEANPADKRDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVFISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID5643 TaxID=2690307 RepID=UPI001368DEE6 +------RLTDLERAYGARVGVYALATGTGATV-VHRAGERFAFCSTFKALAAAAVLHHRT +--LNGLDRRVTYTEADLRSTAPVTGRHVATGMTLRELCDAAVRFSDGTAGNLLMRDIGGP +PKLTAYLRSLGDEVSRMDHYEPELHDVPPGDPADTTTPQAIATDFRRLLLGTALPARERR +LLMDWLSRNATGARRIRAGLPGDWKVADKTGTGDYGRANDIAVVHPPRTEPLVLAVMTDR +PGRDAEPSDALIAEATRRT---- +>[subseq from] serine hydrolase n=1 Tax=Georgenia sp. ZLJ0321 TaxID=2483797 RepID=UPI000FDB9C8A +-----------AAAAGVTLSVSVTDLADGTTV-QSGEDARLKAASIIKLALLATLMADVD +AGELSLDQVVTIPAGDIVGGSGTLRDRTFPLITVRELAELMVQVSDNTATNVLIDVAGGF +DAVNDHVRDLGLEDLHLGRKMI--HPASPPLGENYITAAETTELIALIWHGQILSPTSSE +YIVDLMRGQLV-DTKYGAVIP-RPHLANKTGELAD-VSHDAGIILLPGRE-IALTTTTSF +GSIPRAEADAFVQETAQVVYD-- +>[subseq from] serine hydrolase n=1 Tax=Georgenia sp. ZLJ0321 TaxID=2483797 RepID=UPI000FDB9C8A +----------AENGIRVAVGYSDLTAEDGRLL--LGSPEPYNPASVIKLSLLATVMRQAE +RGLLDLDAPITISPYMVVGGSGTLQNEEPFTTTVREVARRMVVVSDNTATNVLLYYT-GI +PTTQALLDDLGLEVMRFNRQMFP--GDLIDSPPNVIDAADTLTLLEEMYRGDLLTTASRD +QILTWMSQQEV-DTKFGAVLG-DKPIAHKTGETGN-VTHDTGYFLVPGHE-SAVVVLTEV +TDETQRIGNPVVQDIGLAIYDY- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis xylanica TaxID=589385 RepID=A0A1H3R4Y0_9PSEU +--AAEKALAALETEWKGRLGVYALDTATGAAI-GHRADERFLMCSTHKALVAAAILKLRT +DRPGLLDKVIRYDKSQLQKHAPTTSQHVAEGMTVSALCEAAVTVSDNTADNLLFAELGGP +QAATAFVRTLGDQVTRMDRIEPDLNVG--GDERDTSTPAQLAADLRALVLGDALDPAGRD +LLAGWLKANTTGGKQIRAGVPSGWVVGDKTGSGFEGEINDIAVVWPPGRAPLVITVFTAP +ADPKSTAGAETVAKAATIVAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix texasensis TaxID=103734 RepID=UPI000F4C965C +------HLIELERKFDARLGVYAVATGTGTTL-AYRADEPFAFCSTFKGLAAAAVLHRNP +--LSHLDTVVTYTEDDLMASSAVTRRHVATGMTIRQVCDAAVRHSDGTAGNLLLRDLGGP +AALTAYARGLGDTVTRSDRFEPDLTTAVPGDPRDTTSPRAIGVDYQRIVLGDALGPDQRA +FLRDLLERNATGAHRVRAGVPRGWAVADKTGTGGYGTVNDIAVVWPPDAAPLVISIMSSK +ATADAARDQALLAEAAAYAV--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S164 TaxID=1394697 RepID=A0A0I9QPZ9_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSLGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID2563 TaxID=2690255 RepID=UPI0013714F41 +---TTARLRELERTHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD +RDGEVLEKVIRYTKADIVPDSPVTGTALASGLSVARLCDAAIGDSDNTAANLLLRELGGP +QAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTTPSALARDYARLVLGKVLEPRDRE +RLTYWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYASCNDVGVAWTPEGVPVVLAVLTTK +PASDAAGDHPLVRDAAEALA--- +>[subseq from] Beta-lactamase n=1 Tax=Acrocarpospora pleiomorpha TaxID=90975 RepID=A0A5M3XAZ6_9ACTN +--------------------MYALATGTGATV-TYRADERFAFCSTFKALAAAAVLHQNP +--LSHLNKRVTYTSAEVNSISPITEDHIATGMTIRQLCDAAVRYSDGTASNLLVRDIGGP +AQLTAYLRGLGDTVSRIDNYEPELNRNPPRNPRDTTTPRAIAADYHKLVLGDALTTGKRA +MLKDWLERNTTGDKRIRAGVPQGWTVADKTGTGNYGRANDIAIVWPPNTAPLVMAIMSDR +SGYSTPHKESLIAEAAARIV--- +>[subseq from] class A beta-lactamase n=1 Tax=unknown TaxID=N/A RepID=UPI0014399DE1 +---LTGKLRDLERQHNARLGVFATDTGSGRTV-LHRADELFPMCSTFKTIAAAAILRRDH +-DGSLLGKVIRYTQEDVTKYGPITGKNLANGMTVSALCEATITYSDNCAANLLLRELGGP +TAISRFSRSIGDPVTRLDRWEPELNSAEPGRTTDTTSPRAIGQSYARLTLGHALNRTDAD +QLTKWLLANTTGDNRIRAGLPAAWRWGDKTGTGKYSTTNDVGIAFPPGRAPIMIAVLSTK +KDPNGAADEPLVAKTAELVAGI- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00044F3EC7 +------ELVSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI000258660A +------ELVSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075970DB +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +AGADASPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075911D4 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +AGADASPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces palmae TaxID=1701085 RepID=A0A4Z0HG85_9ACTN +-----ARFAALEREYGARLGVYALATGSGAAV-AYRADERFAFCSTFKALAAAAVLDRNP +--LSHLDKRVTYSRADVDSISPVTEKHIATGMTIRQLCDAAVRFSDGTAGDLLMRDIGGP +ARLTAYLRGLGDTVSRMDDHEPELNRIPPHDPRDTTTPRAIAADYRELILGSALAPEKRA +LLKGWLQGNATGAKRVRAGLPRGWVAADKTGTGDYGRANDIAVVWPPHAAPLVLAVMSDR +RGYGASPKDALLADAARLVVS-- +>[subseq from] Beta-lactamase n=1 Tax=Jiangella sp. DSM 45060 TaxID=1798224 RepID=A0A1H1Z4K9_9ACTN +------AVRELERAHDVTLGVSATNLATGARL-AHRSGDRFPILSVFKSIAAAAVLRDLD +--ESRLEHRVWYPPADIVLNSAITAEHVDTGMTVAELCDAAIRFSDNAAGNLLLRELGGP +RGLTAFARSIGDDATRLDRWEIELNSAEPGDVRDTSTPAALARTLAGLLVGDLLRPRDRR +RLRDWMLANTTSGPRFRDALPDGWRLADKTGAGDYGTNNDAGVAWNPAGQPIVIVAMSRR +DERDAPRVDAALADVARLVVR-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A119UQU2_9BURK +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELAPGSPITERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderiales bacterium PBB5 TaxID=2015567 RepID=A0A257JLU5_9BURK +-rALQASLAAIERRSGGRLGVHILHTGSGRHW-GWRSDERFPMCSSFKLLLVAMALSAQA +QGQLGLDERLRYGAGELVANSPITEAHVAQGMTVAELCAATLATSDNTAANVLLARLGGP +AAFTQHLRGLGDEVTRLDRYEPQLNGPGTQPDWDTSSPAAMARSLHRLVLGDGLPAAQQQ +QLIGWLQASVTGGRRLQAGLPSGWRIAEKTGTSN-GSTNDMGVVWPASGAPLVVVGFIRN +SRAPFAVREACLADVGRLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albofaciens TaxID=66866 RepID=UPI001239445D +-----RRLRALEREHQARVGVFALNLATGATL-LHRAHELFPICSVFKTLAAAAVLRDLD +HDGTQLSRVVHYTAADVTKHAPVTKDHIDTGMTIRALCDATIRYSDNCAGNLLLRELGGP +TAITRFCRSLGDPVTRLDRWEPELNSAEPDRRTDTTAPYAIARTYQRLVLGNALDRPDRA +LLTDWLLRNTTSVERFRKGLPKDWKVADKSGGGSYGTSNDVAIAWTPDGAPVVLALFTHK +PTQPTASGDPLVVKAA------- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B7269 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFSQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Herbidospora sakaeratensis TaxID=564415 RepID=UPI0012FA0E65 +-----ADLRALETSFKGRIGLYAIDTATGKTI-AYRSGERFPLASTFKAVLAAAVLDKKP +---DILGKRIPIRKKDLVDYSPEVEKHVGSRMTVAALARAAVTKSDNAAANLLLRQVGGP +KGLTRYFRSLDDHVSRLDRNEPGLNLWHPAELRDTTTPAAVARDLKDLTAGDALDAGDRR +TFTGWLVANETGDKRIRAGLPKSWRVGDKTGTGGYGTANDIAIIWPKGSKPIIMAIYTNR +TDRNAAADDSVVARTATIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Saccharothrix texasensis TaxID=103734 RepID=A0A3N1HJZ1_9PSEU +------HLIELERKFDARLGVYAVATGTGTTL-AYRADEPFAFCSTFKGLAAAAVLHRNP +--LSHLDTVVTYTEDDLMASSAVTRRHVATGMTIRQVCDAAVRHSDGTAGNLLLRDLGGP +AALTAYARGLGDTVTRSDRFEPDLTTAVPGDPRDTTSPRAIGVDYQRIVLGDALGPDQRA +FLRDLLERNATGAHRVRAGVPRGWAVADKTGTGGYGTVNDIAVVWPPDAAPLVISIMSSK +ATADAARDQALLAEAAAYAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075C41DE +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHDSGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAMLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2J0V3F4_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLQSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAQGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. 17Sr1-43 TaxID=2202828 RepID=A0A2U8VMY6_9RHIZ +----AARLAALAARVGGRVGVALRDTAIGETLlSLRAEERFPLCSTFKVLAAAAILARVE +RGAERLERALPLGPEDLQSYAPVARAKVEAAMTVEEACAAALLWSDNTAANLLLAALGGP +GALTAFLREQGDATTRLDRTEPDLNTAIPGDPRDTTTPAAMAATLDRLLLGDGLAPASRA +RLEGWMVESRTGLKRLRAGLPAAWTVGDRTGTGENGTANTVALLRPLGRAPLIATVYITG +LDGPVEARDAPHAEIGRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides salmoniphilum TaxID=404941 RepID=UPI00099264E0 +-----TELASLEKDFGGRVGVYALDTGSGATL-SHRANERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYTQSDVLEWAPVTSQHVAEGMTVSELCDATIRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVIDEGLDSQGRD +LLTDWLKRNTTGDQSIRAGVPAGWTVGDKTGSGFKGETNDIAVIWPPGRAPIVVVVLTVP +DDPKSTKGKPTIAAATRIALKAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007607D3B +--AAQAQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMKIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] BETA-LACTAMASE PSE-4 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI0000113014 +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVNNQVTGNLLRSVLPAGWNIADKSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMEERNDAIVKIGHSIFDVy +>[subseq from] serine hydrolase n=1 Tax=Georgenia sp. ZLJ0423 TaxID=2483799 RepID=UPI000F08B4E5 +-----------AATAGVTLSVSVTDLADGTTV-QSGEDARLKAASIIKLALLATLMADVD +AGELSLDQVVTIPAGDIVGGSGTLRDRTFPLITVRELAELMVQVSDNTATNVLIDVAGGF +DAVNDHVRDLGLEDLHLGRKMI--HPASPPLGENYITAAETTELIALIWHGQILSPTSSE +YIVDLMRGQLV-DTKYGAVIP-RPHLANKTGELAD-VSHDAGIILLPGRE-IALTTTTSF +GSIPRAEADAFVQETAQVVYD-- +>[subseq from] serine hydrolase n=1 Tax=Georgenia sp. ZLJ0423 TaxID=2483799 RepID=UPI000F08B4E5 +----------AENGIRVAVGYSDLTAEDGRLL--LGSPEPYNPASVIKLSLLATVMRQAE +RGLLDLDAPITISPYMVVGGSGTLQNEEPFTTTVREVARRMVVVSDNTATNVLLYYT-GI +PTTQALLDDLGLEVMRFNRQMFP--GDLIDSPPNVIDAADTLTLLEEMYRGDLLTTASRD +QILTWMSQQEV-DTKFGAVLG-DKPIAHKTGETGN-VTHDTGYFLVPGHE-SAVVVLTEV +TDETQRIGNPVVQDIGLAIYDY- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. CH32 TaxID=2530383 RepID=A0A4R4XJE1_9ACTN +--QAKKELRDLERSLGVRIGAYAIDTATGRTI-GYRSGERFALASTFKAMAAAAVLHKAR +TEPGLMDKVVKWTAAELKPNSPITEKHVKDGLTVAQLCHAAITRSDNTAANMLLKQLGGP +AGLTRYFRTLKDPISRLDRWETELNDWSPKEKRDTTTPAAIARDLRLVTAGDALPAKDRE +RLNGWLVANTTGDARIRAGLPASWIVGDKTGTGGYGTANDIAVAWPKKGAPVIMAVYTNG +RTAGAAAQDKALADTATILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=UPI000E16B556 +--------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD +RKALALSASTQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP +QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE +QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ +TPATMAQRDAAIVRIGESLF--- +>[subseq from] Beta-lactamase n=1 Tax=Paraglaciecola arctica BSs20135 TaxID=493475 RepID=K6Z612_9ALTE +--EFTSKISALENNSGGRLGVSVISANGSALY-TYRENERFAMCSTFKALLGAAILSKVD +SNLESLDRAIPYTTKDILDYAPITKRNLSVGMTVSELSAASIQYSDNTAANLLLDAIGGP +QALTSYLRSIGDNQTRLDRNEPSLNTNITGDLRDTSTPNAMAETLHKVMFGDDLSPASKE +QLKAWMFGNTTGANKLKAGFNKFWIVGDKTGSCGNGASNDVAIVYPRGTEAFIISVFYTG +SSASNDIKNAVIADVAQIT---- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0007A04AEE +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLSEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia sp. LLH-Slr-13 TaxID=1564788 RepID=A0A097SRS0_9BURK +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLXRID +AGQEQLGRRLHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTSELLTLASRQ +QLIDWIEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRI------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces pristinaespiralis (strain ATCC 25486 / DSM 40338 / CBS 914.69 / JCM 4507 / NBRC 13074 / NRRL 2958 / 5647) TaxID=457429 RepID=D6X962_STRE2 +-----RAFARLQREFDARLGVYAVDTGSGRTV-THRPDERFAYCSTHKALTAAAVLEHNS +--LAGLDKVVRYTRDDLVAHSPVTEKHVDSGMTLRAVCDAAVRYSDNTAANLLFDELGGP +KAFQAVLAALGDTTTHADRLETALNAATPGDIRDTSTPRALAHDLRAYALGDVLDAEKKA +LLTHWLKGNTTGDALIRAGVPDTWQVGDRTGAGAYGTRNAIAVAWPPGAAPVVIAVLSSR +AENS-PIAKAAF----------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Go-475 TaxID=2072505 RepID=A0A2Z5K4V4_9ACTN +-------LADLERAYGARIGVHALATGTGATV-VHRADERFAFCSTFKALAAAAVLHHRS +--PHDLDRRVTYTRADLRSTTPITGRHLATGMTLRQLCDAAVRFSDGAAGNLLMREIGGP +AQLTAYLRGLGDKVSRMDHYEPELHDVPPDDPSDTTTPRAIATDFHRLLLGTALPARDRA +LLMDWLSRNATGARRIRAGLPRGWKVADKTGTGDYGRANDIAVVHPPRAEPLVLAVMTDR +PGRDAEPSDALIAETTRRTV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE4B2F +---AQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERV +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Desulfoluna spongiiphila TaxID=419481 RepID=UPI00125EF241 +---LENRIKEIEHALGARVGVSLYEVETSESW-SYKGDIRFPLMSTFKTLACAKTLLDVE +QKKVSFDDSVVIEKTSLITWSPVTKHHAGQAFSLKQACAAMMIMSDNTAANIVLDKTGGP +TALTAFMRSIGDAVTRLDRMEPELGEALEGDVRDTTTPNAMADSLHVLLFGDVLSKASKT +QLTQWMRSNKISGSLLRSVLPDGWTIADRSGAGGHGSRGITAVVWPETQPPFIVCMYLTQ +TKASFDERNKAIAEIGRELFKLy +>[subseq from] class A beta-lactamase n=1 Tax=Kineosporiaceae bacterium B12 TaxID=2609562 RepID=UPI0014300498 +--QLEAAFTGLEAEFGARVGVYAVDTGTGAVV-EHRADERFAHASTIKVAAVAAVLDAAT +--PADLDEAVPVPADGIVTHSPVTAAHAGGAVPLREVLAAALTVSDNTAGNLLLDRAGGP +AGLQAFLRTAGDDVTRVDRREPDLNTAVPGDPRDTTTPRALAADLRAFAVDDALGADDRA +VLTDLLRRSTTGAGLVRAGVPAGWGVEDKSGTGGYGTRNDAAVVRPPGRAPLVVVVMSSR +PGADAEPDDALLARATEVVV--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. Leaf70 TaxID=1736233 RepID=A0A0Q4QFW8_9GAMM +----AAGFAALEAESGGRLGVCLWHPASGARF-GHRMDERFPMCSTFKFLLAAAVLHRAG +RGRLSLDQRVPVRKVDILGNSPVTARHAGKDLSVRDLCRATLTTSDNAAANLLLPLVDGP +AGLTAFLRAQDDAVTVAARYEPEANRFAPGDPRDTTSPAAMAGNLQRFVLGDVLDEASRR +QLADWLIDNETGAARLRAGLPGGWRVGDKTGGNGRDTTNDIALLWPEGGSPWVLAGYLQG +SALDDDGRNAILRRVGEVAGD-- +>[subseq from] Beta-lactamase n=1 Tax=Leifsonia sp. 98AMF TaxID=1798216 RepID=A0A1I4RGV7_9MICO +--AAARALAELESQYGATVGVYAVDTGTGRSV-GYRQDDRFAYASTSKVLLAGAVLARSS +--DEQLDAVVPYTSDDLVSYSPITETMAGAGMPLRDVIAAALQKSDNTAANLLFRQLGGP +AELEKSLRALGDETTEVERTEPDLNEAAPGDPRDTSTPRALAADLRAYALGEELPANRRK +LLVDDMTGNATGDPLIRAGAPTGWTVSDKSGAASYGTRNDIAVLTAPGHAPVVMVVLSRK +ADKDAAYDNALVADTAKVL---- +>[subseq from] Beta-lactamase (Fragment) n=5 Tax=Rahnella TaxID=34037 RepID=D7PIH9_9GAMM +-----------------------------SQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP +QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PEKDAK----------------- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura macra TaxID=46164 RepID=UPI00082F657A +------RLSELERSYKGRIGAFALDTGNGRVV-SYRAHERFPFASTFKAMTGAAILHKAR +RDPGLLDRRLHWTKKDLLPNSPITEQHVEDGLTVAELCHAAITRSDNTAANVLLGQLDGP +AGLTRFLRSIKDPVSRLDRYETDLNIWKPGQKRDTTTPAAVGRDLAGLAVGRTLAPPDRA +RLNGWLRANLTGDARIRAGVPKGWIVGDKTGTGSYGTANDIAVVTPPHHAPLIIAVYTNR +KDPKGQADESVIARTTSILVD-- +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=A0A078LI87_CITKO +---------QEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD +RKALALSASTQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP +QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE +QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ +TPATMAQRDAAIVRIGESLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella genomosp. 13 TaxID=463040 RepID=UPI0011A7F404 +--DLGQVLADLEKQSQGRLGVALTDTATGQVA-SHRGDERFMMLSSFKTLSAAYILARAD +RGEEQLARRIPIAQSDLLDHAPVTKQHVGARMTLAELCHATITTSDNTAANLMHRSYGGP +QALTRFVRSLGDPITRHDRYEPELNVPHVSEPLDTTSPHAMNRTLGALLFGQALKPESRR +MLQSWLVANQTGGTRLRAGLPSDWTVGEKTGTYSKVGANDAGFARAPGGAPIVVSVYLET +TAIDMPERDRIIAEVGRLVA--- +>[subseq from] L2 family class A beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6B8J7H5_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLQSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAQGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio rotiferianus TaxID=190895 RepID=UPI000B598546 +--KLNEDLAAIEQHIGGRIGVSVWDTQNDEHW-DYRGDERFPMMSTFKTLACATMLSEMD +SEKLDKNATAKVEERNIVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +NGVTRFLRSIGDGATRLDRFEPRLNEAKPGDKQDTTTPNAIVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGIMAMIWKENHKPIYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] Beta-lactamase n=1 Tax=Bacillus manliponensis TaxID=574376 RepID=A0A073JSD7_9BACI +--TVIEKFEQLEKEYDARLGVYAIDTGTKETI-EFRENERFAYTSTFKALAGAVLLKQNP +--ISALEEIRTFTDEDIVTYSPITEDFVNKGMSLGEIAKAAIQYSDNTAGNLLFEELGGP +DGFEKALRESGDTITMADRIEPDLNEAIPGDSRDTSTPKALATTLEVFGISEYLPADKQE +IFTNWLKGNTTGDSLIQAGVPEGWEVGDKSGAGSYGTRNDIAIVWPPNREPIVIAVMSSR +KEENASFNDELIAKATKVITQAf +>[subseq from] class A beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=UPI0009BAE122 +--------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD +RKALALSASTQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP +QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE +QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ +TPATMAQRDAAIVRIGESLF--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. OK270 TaxID=1882814 RepID=A0A285DYY1_9NOCA +--SLDTKLDALEARYSTRIGVTAIDPATGQIY-QHRGDERFALCSTFKTYAAAEVLRRTR +AGTSSLDKPVLVEPGDLVENSPVTAAAVGTPMTLRQIAEAALTRSDNTAGNYLLEEIGGP +PAITSLAREIGDESTRLDRWETELNSALRGDPRDTSTPKELADGYQALLLGDALRSPERA +QLVDWMRASKTSDKRIRAGLPDGWTAAAKSGAGRFGTVNDAGVAWDRDGNPLVLAILTDS +LTEDAQGNNQVVADTTAAVVE-- +>[subseq from] Beta-lactamase n=2 Tax=Citrobacter koseri TaxID=545 RepID=Q708V4_CITKO +--------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD +RKALALSASTQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP +QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE +QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ +TPATMAQRDAAIVRIGESLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758E346 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC401 TaxID=1848324 RepID=A0A5R8MX89_9ACTN +--RATKELRALETSFKGRIGAYAIDTANGRTI-AYRSDERFPLLSTFKAMACAAVLHKAR +TQPGLMNKRVRWTARDLVDYSPVTEKHVKDGMTVAGLCHAAITMSDNTAGNLILKQIGGP +AGLTRYFRSLKDRVSRLDRWETELNDWTPKSRRDTTTPSSIARDLRAVTYGKALNAKDRA +RLNAWLIANKTGDARIRAGLPKTWLIGDKTGTNSFGGGNDIAVIWPKRAAPIIMAIYTNR +RP-GLAADDKTIAKTAEVLA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0006A7068E +--KLNEDISLIEKQTSGRIGVSVWDTQMDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNQIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI00062BF411 +-sQLNEDISLIEQQTSSRIGVSVWDTQTDDRW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRSIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLIAQISQLILQKy +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia ninae TaxID=356145 RepID=UPI0011BE9039 +-----PRFVELEQQFGARLGIYALSTGTNRTL-THRADERFAFCSTFKALAAAAVLHHNP +--LTHLDKPVTVTKADIRSISPVTEKRVDTAMTIGELCDAAVRFSDGTAGNLLLDDIGGP +AGLTGYLRGLGDPVSRMDQYEPELNRDPPGDDRDTTTPRAIAADYQQLILGSALPEDKRA +ILTDWLVRNMTGAKRIAAAAPAGWTIADKTGTGDYGRANDIAIVWPTSHPPLVLAIMSDR +TGYDAEPSSELIAEAARHIF--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SLBN-192 TaxID=1119093 RepID=A0A542TVH3_9ACTN +-----PRLADLEREYGARVGVYALATGTGATV-VHRAGERFAFCSTFKAPAAAAVLHHRS +--ASGLDRRVTYTEADLRSTAPVTGKHVATGMTLRELCDAAVRFSDGTAGNLLMRDIGGP +AALTAYLRGLGDTTSRMDHYEPELHDVPPDDPADTTTPQAIATDFRTLLLGTALPLRERR +LLMGWLSRNATGARRIRAGLPGDWKVADKTGTGDYGRANDIAVVHPPRSSPLVLAVMTDR +PGRDAEPSDALIAEATRRTV--- +>[subseq from] Carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A660AGX4_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLASATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ok210 TaxID=1761905 RepID=UPI000B876E44 +--RTARELRALEREHSARLGAYAHDTATGRTV-VYRPDERFPMCSLFKTIGAAAVLRDLD +RRGEFLARRIRYTAQYVEANSPITGRNLSGGMTVAELCAYSITHSDNTAANLLLRELGGP +GAVTRFCRSIGDPVTRLDRWEPELNSAEPWRGTDTTTPRAVGRTYARLVLGDALVPCDRR +LLTGWLLANTTSGERFRAGLPADWTVADKTAGGSYGGNNNAGIAWPPGRPPVVLAVMTTK +PDRDAPADNPLVARTAGVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075CF16A +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTVGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Alcanivorax xenomutans TaxID=1094342 RepID=UPI0009B6DC0B +--ALGHRCQEWERRHGGRIGVAVWNLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD +QGQESLDRRLLVSRKDLVGWSPVTGKRTGEGMTVAELCEAAVAWSDNGAANLLVKGFGGP +GALTEFLRENGDPVTRLDRLEPELNGYGPDGEYDTTSPAAMLETLHRLLFGEVLSAHGRA +QLAAWMIANKTGDRRLRAGFPANWLVADKTGTSGLGYSNDIGVAWSPARGAVLVTVYCEM +PKAEAEARDRIIAEVAEI----- +>[subseq from] class A beta-lactamase n=1 Tax=Erwinia oleae TaxID=796334 RepID=UPI00068A72C9 +------KAQAIEKRLNARVGMAVIDTGSDRRW-LYNAEARFPLNSTFKAFACGALLYQAD +AGKNDLNKATRVTREEMIPYAPVAEKLIGQSVSLDRLCAATMRTSDNVAANKILASIGGP +EGMTHFMREIGDSVTRLDRREPDLNEAMPGDLRDTTTPAAAVASLRKLVLGNVLSVASRE +KLTRWMIEDAVGGPLLRAGIPSAWRIGDRTGAGGHGSRSVIAVMWPPSHAPVVVAVFITE +TTATMEVRNAAIAELGAALAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. D16R12 TaxID=1855662 RepID=UPI000993911C +-----TELASLEKEFGGRVGVYALDTGSGATL-GHRPNERFLMCSTVKTFIVSAVLHRRL +SEPGLLDKQIHYAQSDIMEWAPVASQHLAEGMTVSELCDATIRYSDNTGANLLISLLGGP +KQTEKFVRSLGDNVSRMDRTEEQLN--VPDGDLDTSTPLQLVTNLRRLVLDQGLDPQGRD +LLTDWLKRNTTGDQSIRAGVPAGWTVADKTGSGFKGETNDIAVIWPPGRAPIVVAVLTVP +DDPKSTQGKPTIAAATRIALKAf +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=A0A1B4C018_9BURK +--AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPERA +QLTEWMTGGARSATGIAAGVPPGWRIADKIGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATSAf +>[subseq from] Class A beta-lactamase n=1 Tax=Saccharopolyspora sp. 16K309 TaxID=2530384 RepID=A0A4R4VY68_9PSEU +--------AELERRYDARLGLFARNVATGRTI-AHRADERVALCSTFKVYASAALLRAHG +LASGYFDRVIRYDAGQLVKNSPITETRVDTGMTVGELCAAAVQHSDNTAANLMLRELGGP +QAITEFARGIGDPMTRLDRWEVELNTAIPGDERDTSTPRALGEGLQHLLLGDALGPAERD +RLTGWMLGSATGAARIRAGVPSSWRTADKTGGGAYGVANDIAVTWTDTGTPIVISLLTGR +PREHDTANNALLADAARLVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MMLR14_010 TaxID=1898743 RepID=UPI0009F4ADFA +--ATARAFRTLERDHGARLGVTAIDTGSGQRV-TYRSGERFPFASTNKVFVAAVVLAQSS +--GADLDTVVHYDRSDLLAHAPVTTRSVDTGMTVRALLDAMLRYSDNTAANLLVERVGGP +AVVEQALRDLGDRTTNVDRVEPDLNEAVPGDARDTTTPAQFAADLRQVLLRSALDPSDRR +MLRESMLGNTTGDATIRAGVDPAWAVADKTGTGSYGVRNDIGIVFPTGRAPIVVVVMTSK +DTADAEPDDALVAAATRTAVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Belnapia moabensis TaxID=365533 RepID=UPI0005B9AAA1 +---AAEGLAALEARQGGRLGVAILDSGSGRVL-AHRGEERFALCSTFKHLAAARVLARVD +AGEEWLDRHVAYGREALVPYSPVTGPGAEAGLAMGAICEAAVALSDNTAGNLMLDSFGGP +AGLTSWLRGLGDGATRLDRRETELNVVPPGDERDTTTPLAMVGTMRRLLLGEALSAGSRE +RLVGWLVGSKTGDARLRAGMPAGWRVGDKTGTGPAPPTNDVAIAWPPGQAPVIVAAYLEG +ARGSDAERSAVLAEVGRVAA--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. WZN-1 TaxID=2005046 RepID=A0A1Z2LMX5_9GAMM +-----ADFAALEKASGGRLGVTVLNTGDGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVDKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. YR399 TaxID=1884371 RepID=A0A2M8VUM4_9GAMM +----ASDFAALEKACSGRLGVTLLDTGSGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDPALLDRRLPVRATDILEHAPVTRRHVGKDLAVRDLCRATLITSDNIAANLLFAAIGGP +PAVTAFLRASGDTITRSDRLEPELNSFAIDDPRDTTTPAAIAATLQRLVLGDALKPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWIVTAYLQA +GAISFEQRAAVLAQVGRIA---- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter glycinis TaxID=582702 RepID=A0A1I3Z3F5_9GAMM +--AIAGELATLERQHGGRLGVAMLDIGSGRHA-GHRAGERFLLCSTGKLLVVGAVLARVD +RGEEQLSRRIVFGPDVILEWAPVTRKHVGAPMTVAELCHAALTISDNTAMNLLLKSVGGP +AAATRFVRSLDDDITRLDRHEPELN--VPDRNLDTTTPDAMLASLRKLLLGNVLSASSRA +QLIDWLRHNTTGETQLRAGMPASWQAGDKTGSGHT-QTNDVAIAWPPGRQPLLVTAYYEG +PADQGDMRKAVLAHVGKLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudorhodobacter sp. MZDSW-24AT TaxID=2052957 RepID=A0A2M8MUY0_9RHOB +-dRLAATIERIERDLDARVGVVIRDSGSAWSL-GHRADERFLMNSTFKTMLCGAVLRRVD +DGVLSLDEDIAIRDSDLLDYAPVTETMVGKSMSIGELCFAALDMSDNTATNLLIDRIGGP +QSVTAFLRDIGDPVSRLDRREPDVNNFAPGDPRDTTTPDAMALTMDALLNKDALTAESRA +RLVDWMSAGGVTGALIRASTPEGWQVADRSGSGDF-NRNIAAMVTPPGKAPYFISIFLSD +ADADFATRNAAVIALSEAVMQ-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI000996A535 +--KLNEDISLIEKQTSGRIGVSVWDTQMDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLAGQRTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. KhCrAH-43 TaxID=1305827 RepID=A0A327V7D7_9ACTN +---TTARLRELERAHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD +RDGEVLEKVVHYTEADCVSDSPVTDTHLESGLSVARLCDAAIGDSDNTAANLLLRELGGP +AAVTRFARSLGDRVTRLDRWEPLLNSAEPGRVTDTTTPSALARDYARLVLGNVLERRDRE +RLTYWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYGSCNDVGVAWTPGGVPVVLAVLTTK +PASDAAGDHPLVRDAAEALA--- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia piptadeniae TaxID=1701573 RepID=A0A1N7RYR2_9BURK +---AHKRFEQLEARSGGRLGVAALNTADGAYV-GYRESERFPMCSTFKLLAVAAILKRSI +AERALLDTHIRYGETDLVANSPVTKRHVSEGMSMGDICAAALQYSDNTAANLLLTALGGP +EVLNEFARSIGDTWFNLVRREPELNDAVPGDMRDTTTPRAMMHDMQKILLNDVLEPPQRE +KLKTWLLGNTTGERRIRAAVRTGWPVADKTGSGDYGTANDVAVVYSPAAA-FVVAVYCTG +LTKETPPQDEVVDEAARIVFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007596253 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMKIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. XY006 TaxID=2021410 RepID=A0A231P6Z6_9ACTN +------RFADLERAYGARVGVYALATGTGATV-VHRAGERFAFCSVFKALAAAAVLHHRS +--PHDLDRRVTYTRADLRSTTPVTGRHLATGMTLRELCDAAVRFSDGAAGNLLMREIGGP +GKLTAYLRALGDRTSRMDHYEPELHDVPPDDPRDTTTPEAIATDFRRLLLGTALPAGDRA +LLLDWLSRNATGARRIRAGLPRGWRVADKTGTGHYGRANDVAVVHPPRGEPLVLAVLTDR +PGRDAEPSDALIAEATERT---- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium pseudokansasii TaxID=2341080 RepID=A0A498QTM3_9MYCO +--DLQSRFAELEHRYAARLGVYVPATGTTAAI-AYRADERFAFCSTFKALLVAAVLHQHP +--LSHLDKVVTYTSADIRSISPITQQHVATGMSIGELCDAAIRYSDGTAANLLLAEVGGT +SGFTGYLRGLGDSVSRLDQEEPELNRDPPGDERDTTTAHAIALDYQQVVLGEALPPDKRA +MLTDWMARNTTGANRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPAGVSHVVAILSDR +APYDAEWSEALIADAARCVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia vaccinii TaxID=1822 RepID=UPI0009FE47EA +---LSGRFGALERRFGARLGVFALDTGSGRTV-EYRADERFAFCSTFKALEAGAILATAG +--PAELERRISYTATDFTAYAPIARQHVADGMTVRELLDAAVRYSDNTAANLLFGLLDGP +PGLQRDLRNLGDQVTRSDRVEPALSQAVPGDPRDTSTPRAIAADLRAYVLGNTLPTDGRA +LLTTMLRTNTTGAGLIRAGVPADWVVGDKTGNGDYGTRNDIAVLWPPHRAPLVLAVMSTR +GGRDDSFDNALIAQSANVAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. BA2 TaxID=436595 RepID=UPI00132454A2 +--ELAKQLSGLEQEYSARLGVFARDTVTGRTV-TYRADEHFPMCSVFKTLAAAAVLRDLD +RNGTFLAQRIRYTSEDAMNYHPITGRNLADGMTVGELCAAAVSHSDNGAANLLLRELGGP +TAITRFCRSIGDKTTRLDRWEPALNSAEPWRKTDTTSPRAIGHTYARLILGNALAGEDRS +RLTGWLMSNTTNGERFRAGLPADWTLADKTGGGEYGVANDVGVVWPPGKSPLVLAVLSTK +HAPEGPTDNPLVAKTVTL----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces cacaoi subsp. cacaoi TaxID=66857 RepID=A0A4Y3QVW9_STRCI +--AHEKEFRALEKKFDATLGVYAIDTADGQEI-THRADERFAYGSTFKALQAGAILRKFS +AEADGMDKVVHYGQDAILPNSPVTEKHVADGMSLRELCDAVVRYSDNTAANLLFDQLGGP +KGLNAVLKQLGDHTTSMDRYEQELGSAVPGDPRDTSTPRAFAEDLRAFAVEDALAPNDRE +QLNDWMSGNATGDALIRAGVPKDWKVEDKSGQVKYGTRNDIAVVRPPGRAPIVVSVMSHG +DTQDAEPHDELVAEAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI000F597FB8 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNQAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PEATAAARADVVASAARLAA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011226CF7 +--KLNEDISLIEKQTSGRIGVSVWDTQMDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTN +TDLSLQARDQLIAQISQLILEHy +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111F2CEA +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGGERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium kansasii TaxID=1768 RepID=UPI000CDE117E +--DLQNRFAELEHRYAARLGVYMPATGTTAAI-AYRADERFAFCSTFKALLVAAVLHQYP +--LSHLDEMVTYTSADIRSISPITQQHVATGMSIGELCDAAIRYSDGTAANLLLAEVGGT +SGFTGYLRGLGDSVSRLDQEEPELNRDPPGDERDTTTPHAIALDYQQVVLGDALPADKRA +MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPAGVSHVVAILSDR +ASYDAEWSEALVADAARCVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. 9128 TaxID=1793722 RepID=A0A181ZF26_9MICO +--STDRAFAALEHQHDARLGVTAIDTASGHRV-SYRSDERFPFASTNKTFIVAAVLAHDS +--DADLDTIVHYDRSDLLEYAPITSRFVDTGMTVRELIDAAMRFSDNTAANLLVERVGGP +DAVERYLRGIGDRTTNVDRVEPDLNEATPGDDRDTTTPAQFASDLRQVLLGKTLDTTDRT +LLRDTMLDNTTGAGTVRAGVDPAWPVADKTGTGEYGVRNDIAVVYPTGRAPIVVVVMTAT +DRSDAKADDPLVAAATKQAV--- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC712 TaxID=1848329 RepID=A0A4V2YDT6_9ACTN +--RAAKELRALETSFKGRIGAYAIDTATGKAI-AYRSGERFPLLSTFKAMACAAVLHKAR +TRPGLMKKRVRWTARDLVDYSPVTEKHVKDGMTVAALCHAAITMSDNTAGNMVLKQIGGP +KGLTRYFRSLNDRVSRLDRWETELNDWTPKSRRDTTTPSAIARDLRAVTYGKALNAKDRA +QLNAWLIANTTGDARIRAGLPRTWTIGDKTGTNSFGGGNDIAAIWPDKGAPIIMAIYTNR +TP-GLAADDKTIAKTATILA--- +>[subseq from] Beta-lactamase n=2 Tax=Actinomadura meyerae TaxID=240840 RepID=A0A239J9W7_9ACTN +--DVTRQLTRLEKIRSTRIGAYAIDTGTGQVV-GHRADETFPFASTFKAMACGAVLRKAR +QAPGLLDKVIHYTEDDLQEFSPVTEKHVGTGMTVAELCHAAITRSDNTAGNLVLEQIGGP +AGLTAFFRSLGDTVSRSDRTEPGLNLWKPGEKRDTTAPRPWADDLRALTTGNALAPADRT +RLIDWLKATVTGDKRIRAGLPKSWTVGDKTGTGGYGSANDMAIAYPKGGAPLIMVVTTTR +KGEDAAADEKSIALTAGVL---- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura amylolytica TaxID=1411117 RepID=UPI000E6C2975 +--EVRRRLRALEAEYGGRIGAYAIDTATGRTV-GYRAQETFPMLSTFKAMACAAVLHKAR +ADPGLLERVIRYTADDLVDHSPETGKNLKAGMTVSALCEATITLSDNTAGNLVLRQIGGP +AGLTAYLRSLGDPRSRLDRWELELNDWRPGERRDTTTPALMAQNLRKVTTTDALAGPDRA +RLIAWLRANTTGDARIRAGLPGDWTVGDKTGTGGYATANDIAIVWPEGAAPLIMAVYTNR +GTPDATADNTFVARTATILAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium setense TaxID=431269 RepID=A0A0B2YQA1_9MYCO +---IDDQIAELERRDNALIGLYATNLDSGRTI-THRPDEMFAMCSTFKGYAAARVLQMVG +RKQISLDNRVFVDPDAIVEYSPVTEPRAGGEMTLGELCRAALQQSDNTAGNLLLKTIDGP +PGITAFARSIGDQRTRLDRWETELNSAIPGDPRDTSTPAALAGGYREILAGDALSPPQRR +QLQDWMRANET--SSVRAGLPEGWTTADKTGSGDFGSTNDVGIAYGPDGQQLLLAVMTRS +QADDADNLRPLIGELAAL----- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. AU16741 TaxID=2015347 RepID=A0A228HJ42_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTVAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMAGGARGAAGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PDAAAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Ideonella sakaiensis (strain NBRC 110686 / TISTR 2288 / 201-F6) TaxID=1547922 RepID=A0A0K8P1S2_IDESA +--------AGLEAAAGGRLGVAVAG-PSGPLD-GHRLDERFPMCSTFKWLVAARVLQRVD +AGEERLARRLPVTARDLVAHSPVCERHVGATLSLAELCHATITTSDNAAANLLLPALGGP +EGLTRWLRTLGDLVTRLDRWEPHLNEAAPDDPRDTTTPRAMLGLLRTLLLGDVLAPGSRA +TLAGWLEATETNTTRLRAAVPPGWRMGSKTGAGANGATNDVGLYWPPGRPTILVAAFLVG +TSAPTARRHAAIAEVGRRAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0006AC664B +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMAGGTRATTGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PQADAAVRADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. HF10 TaxID=2692233 RepID=UPI001316A8F5 +-----GELADLERRYGARLGVYARNVRTGRVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMADVCAAAIQYSDNAAGNLLLRRLDGP +GGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALATSIERLALGRALAAPDRE +RFVGWLKGNTTSGARFRAGLPAGWTIADKTGTGDYASANDLGVAWTTRRTPVVLAVLSTK +EGKDAPVDEALIAEAARIAAR-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia vulneris TaxID=1141657 RepID=A0A0C1D8U6_9NOCA +----HDRLFELERKFDARLGVYALDTASGATV-THRADERFAFCSTFKGLAAAAMLQRNP +--LSHLDTVVRYTDEDLTKNAAITPQHVATGMTIRDLCDAAVRYSDGTAGNLLLRDIGGP +AELTAYLRGLGDPITRMDRIEPAITEATPGDPRDTSSPRALGTDYQRIVLGDALPEDKLA +FLRDLLERNATGAGRVRAGVPQGWKVADKTGTGDYGTLNDIAIVWPPDRAPLVLSLMSSK +ATADAEYDQALLAEAAAYVVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0002316F31 +-----NELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL +SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP +EDPTSTKGKPTIAAAARIVLRAf +>[subseq from] class A beta-lactamase n=1 Tax=Lentzea flaviverrucosa TaxID=200379 RepID=UPI000B7D7A32 +--TVTGKLRELEKQHNARLGVFAADTGTGRTV-LHRADELFPMCSTFKTIAAAAVLRKDR +-DGTLLGKVITYTQSDVDKHGPITGRNLANGMTISALCEATITYSDNCAANLLLRELGGP +TAISRFSRSIGDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGQSYARLTLGHALNSNDSD +QLTKWLLANTTGGNRIRAGLPSAWRWGDKTGTGSYGTTNDVGIAFPAGRAPIVIAVLSTR +KDPTGAADEPLLAKTAELVAATf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella sp. 344-Salad TaxID=678973 RepID=D7PIJ5_9GAMM +-----------------------------SQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLNRRVSLTRSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP +QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PEKDAK----------------- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase KPC n=1 Tax=Mycobacteroides salmoniphilum TaxID=404941 RepID=A0A4V3I0G8_9MYCO +-----TELDALERDFGGRVGVYALDTGSGATL-SHRANERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYTQSDVLEWAPVTSQHVAEGMTVSELCDATIRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDSQGRD +LLTDWLKRNTTGDQSIRAGVPAGWTVGDKTGSGFKGETNDIAVIWPPGRAPIVVVVLTVP +DDPKSTKGKPTITAATRIALKAf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces pristinaespiralis TaxID=38300 RepID=UPI0009969D0B +-----RAFARLQREFDARLGVYAVDTGSGRTV-THRPDERFAYCSTHKALTAAAVLEHNS +--LAGLDKVVRYTRDDLVAHSPVTEKHVDSGMTLRAVCDAAVRYSDNTAANLLFDELGGP +KAFQAVLAALGDTTTHADRLETALNAATPGDIRDTSTPRALAHDLRAYALGDVLDAEKKA +LLTHWLKGNTTGDALIRAGVPDTWQVGDRTGAGAYGTRNAIAVAWPPGAAPVVIAVLSSR +AENS-PIAKAAF----------- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759A2A5 +--AAQSQLDALERASNGRLGIAALDTVTGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. EC-SD404 TaxID=2038389 RepID=A0A5E7XXE6_9RHIZ +--RLQEVVSTIEEDLGARVGIVVRDTGSDWQW-AHREDERFLMNSTFKSVLCGAVLQRAE +NGELALTDALEIEASDIQDYAPVAETRVGETMTVGELCLATLDMSDNTAANLLIDRLGGP +QEVTAFVRTLGDGVTRLDRWEPEMNTFAEGDPRDTTTPSAMAASWEAMLLGDGLSAAAQD +QLVDWMSIGGVTGALLRASTPDDWLVADKSGSGNR-TRNLVAMVTPPDEAPYLVSIYLSD +TSADFETRNAAVTEVGAAIVD-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111E6003 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIVQISQLILEHy +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=UPI00066A2D0B +--KINEDLAAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLNDMD +NEKLDKNATTKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSVGGP +RGVTMFLRTIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITG +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] Beta-lactamase n=1 Tax=Sulfitobacter pseudonitzschiae TaxID=1402135 RepID=A0A221K3Q0_9RHOB +-eTLEQTVDQIETKLDGRIGISLIDTGSGFTW-SHRQDERFLMNSTVKVPLCGAVLARVD +AGTLSLSEQLPVVQADIQSYAPVTEQRVGQSMNIAELCMAAIDMSDNTAANLLIDHLGGP +QAITQFFRSTGDIESRLDRREPELNTFAPGDPRDTTTPVASTDTLYALLLGDVLSDRSRK +QLADWMSHGGVTGQLLRAKAPAEWQIYDKSGSGSH-NRNLVAMVTPESRAPWIVTIFLSD +MDEDFETRNAALQDISRAVI--- +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=Q708V3_CITKO +--------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD +RKALALSASAQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP +QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE +QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ +TPATMAQRDAAIVRIGESLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756EFE5 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRECFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces viridosporus (strain ATCC 14672 / DSM 40746 / JCM 4963 / KCTC 9882 / NRRL B-12104 / FH 1290) TaxID=566461 RepID=D5ZPK2_STRV1 +------SLADLERAYGARIGVYAVATDTGATV-VHRADERFAFCSTFKSLAAAAVLHRNP +--LSRLDERVTYGRADLAAHSPVTERHVATGMTVRQLCDAAVRYSDNTAANLLLRDLGGP +RGLTTYLRGLGDRVSGLDHYEPELNRNPPGDPRDTTTPRAIAVDHRALVLGDALPAARRA +LLKDWLVRNTTGDRRIRAGVPRGWTVGDKTGTADWGRAHDVAVLWPPRAAPLVLAVL--- +----------------------- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011211AE2 +--KLNEDISLIEIQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Agreia sp. Leaf244 TaxID=1736305 RepID=A0A0S9DWG6_9MICO +------AFAQLEQEFDARLGVYALDPLSRAEV-AYRADERFAYASTFKALAAGILLKTVP +--DEQLDELVSYGADELLPNSPVTEANVDEGMTLRAVAEAAVRFSDNTAGNIVLERLGGP +EGFTQALRDLGDTTSSSDRIETDLNSAIPGDTRDTSTPRAFALDLATLLTTDALGAAQQS +QLIDWMTGNATGSELIAAGLDAGWSVADKSGAGAYGTRNDIALVWPPSGSPIVLVIMSNR +PTEDAEYDNALIARATEAAL--- +>[subseq from] Beta-lactamase class A n=1 Tax=Klenkia brasiliensis TaxID=333142 RepID=A0A1G7SFY2_9ACTN +-------VDALEAAYAARVGVWALDTGTGQVL-EHRADERFAHASTLKLLLVGLLLDRVP +--DAELDAVVPIGADDVLEYAPVTSQHVGTGLPLRELMAAAITVSDNTAANLLVARLGGP +AQVQAALRELGNPTTRVDRVEPDLNEALPGDPRDTSTPADLGATVQQLVLGDVLAPDRRA +LLQQWLRENTTGDAAIRAGVPEGWEVGDKTGSGGYGTRNDVAVVQPDDGAPLVVVLLTDR +GVPDADADDGLLADATRLVVDQ- +>[subseq from] Beta-lactamase n=1 Tax=Comamonas testosteroni (strain DSM 14576 / KF-1) TaxID=399795 RepID=B7WWP2_COMTK +--TLSDELAALEIQSQGRFGLYVVDTVSGAEA-GWRGDERFPMCSTFKTLLAARVLYLAQ +RGEIRLWRKLYYSPAEVVAWSPISEKRAGANMTVQELCEAMVVVSDNTAANVMLEASGGP +AALTQWLREMGDGTTRLDRNEPSLNTALPGDERDTTTPRAMVQSLQKLLLGDVLEGYARA +LLQQWLADSRTGDKRVRSGMPGDWKVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG +SPLDGAGREAVLARAGEAIK--- +>[subseq from] class A beta-lactamase n=1 Tax=Actinoalloteichus sp. AHMU CJ021 TaxID=2072503 RepID=UPI000CA08C23 +---REAAFERVEREHDVRLGVYALDTGSGRAL-VHRPDERFAYCSTIKAVAAGAVLLVSS +--DERMGQVIPYQQGDLVSHSPVTEAHVGAGLGLDALCEAAVRYSDNTAANLMLTELGGP +AGFQRRLRELGDEVTRSDRYETELNDAVPGDDRDTSTPRALATTLRTLLLGDALTDERRA +VLEDWMSGNATGDELVRAGVPSDWRVVDKSGGGFYGTRNDIAVAFRPDAPPIVLAVLTSR +TERDAGGRAEAVAAAAAVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinoalloteichus cyanogriseus TaxID=65497 RepID=UPI000415D6DA +---REAAFERVEREHDVRLGVYALDTGSGRAL-VHRPDERFAYCSTIKAVAAGAVLLVSS +--DERMGQVIPYQQGDLVTHSPVTEAHVGAGLGLDALCEAAVRYSDNTAANLMLTELGGP +AGFQRRLRELGDEVTRSDRYETELNDAVPGDDRDTSTPRALATTLRTLLLGDALTDERRA +VLEDWMSGNATGDELVRAGVPSDWRVVDKSGGGFYGTRNDIAVAFRPDAPPIVLAVLTSR +TERDAGGRAEAVAAAAAVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. GXF4 TaxID=1096546 RepID=I9CK25_9RHIZ +-eAIESALAAIEKRLGGRLGVSAG-TQERVFL-RHRADELFPMCSTFKVLAAACVLARVD +AGTESLDRLVTYGNDVLLSYAPVIRKGLEAGMTVADLCAAALEWSDNSAANLLLTALGGP +QALTLWLRGIGDTVTRLDRNEPTLNTALQGDPRDTTSPEAMRATLARLLLGPSLSAAARA +RLEAWMVASQTGFKRLRAGLPPDWTAGDKTGTGDHGTVNDVAILRPPGRAPILACVYVTG +AQAPTEVVEAAHAEIGRLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Lentzea flaviverrucosa TaxID=200379 RepID=A0A1H9W2Y1_9PSEU +--TVTGKLRELEKQHNARLGVFAADTGTGRTV-LHRADELFPMCSTFKTIAAAAVLRKDR +-DGTLLGKVITYTQSDVDKHGPITGRNLANGMTISALCEATITYSDNCAANLLLRELGGP +TAISRFSRSIGDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGQSYARLTLGHALNSNDSD +QLTKWLLANTTGGNRIRAGLPSAWRWGDKTGTGSYGTTNDVGIAFPAGRAPIVIAVLSTR +KDPTGAADEPLLAKTAELVAATf +>[subseq from] class A beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=UPI000D867AD2 +--------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD +RKALALSASAQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP +QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE +QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPASQKPLLVVIYITQ +TPATMAQRDAAIVRIGESLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=UPI000C9C6B8B +--DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD +RGTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP +EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTATPRSVLSTLHAALSGTMLSGSSSA +QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE +TNADFSRRNQAISDIGRAMI--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptococcus suis TaxID=1307 RepID=UPI000CF58A2C +---------------------------------SFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQA-------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F5953C0 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia cepacia complex TaxID=87882 RepID=A0A1V2XJE8_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=A8AHA3_CITK8 +---------QEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD +RKALALSASTQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP +QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE +QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ +TPATMAQRDAAIVRIGESLF--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=A0A106E519_9BURK +--AAQAELAALEKASDGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTEGHVDTGMTIGQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNQAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA +QLTEWMTGGARNASGIAAGVPPGWRIAEKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] Beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=A0A135IK59_9RHOB +--DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD +RGTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP +EGFTAYMQTSGDLITRLDRWETDLNSATPGDPRDTASPRSVLSSLHAALSGTMLSGSSSA +QLADWMQRDQLADDLIRAHLPEGWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE +TNADFSRRNQAISDIGRAMI--- +>[subseq from] Beta-lactamase n=2 Tax=Tabrizicola piscis TaxID=2494374 RepID=A0A3S8UC22_9RHOB +--RLAETIDRIEQDLNARVGLVIRDSGSDWSV-SQRADERFLMNSTFKTMLCGAVLHRVD +EGDIDLEERIAIEASDILEYAPVTETMVGNTMSVGALCQAALDMSDNTATNLLIDRIGGP +ESVTAFLREMGDPISRLDRREPEVNTFAPDDPRDTTTPAAMVSTMEMLLTGDALTPQSRT +QLVDWMSDGGVTGALIRASTPEGWHVADRSGSGNF-NRNIVAMVTPPDRDPYFVAIFLSD +ADADFDTRNAAVIALSEAAM--- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. TLI_55 TaxID=1938861 RepID=A0A285BTZ0_9ACTN +--STPKGLRELEAQHGARLGVFARNLATGRTV-RHRARELFPMCSLFKTLASAAVLRDLD +RDGEFLSRRIHYTDADLPKGSDKTREHLADGMTVAELAEVAITFSDNGAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWETELNSAEPWRITDTTSPYAIGRTYGRLVLGDALDGPDRA +LLTHWLRSNTTSGTRLRAGLPPAWTVADKTGGGSYGTNNNVGIAWTEDGTPLLLAVLTTK +PAQDAARDDVLIRDTAALLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC04657 TaxID=1779145 RepID=A0A150VKE4_9ACTN +-----------EDAFDARLGVYAIDTGTGREV-AYRDGERFPYASTFKALAAGAVLRKES +--LSGMERVVRYTEDELVDPSPVTEKHVGTGMTLDALADAAVRHSDNTAGNLLFEELAGP +KGLQAVLRSIGDDVTRMDRIEPELGDWRPGEVRDTSSPRALARDLRAFVLGDVLRAPERE +RLTTWLKTNLTGDETIRAGVPDTWVVGDKTGTATYGGRNDMAVVWPPDGAPIVMAILSTR +SDREAKPDNRLIARAASVVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D4DB5 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPEVNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIATSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. ZJ1313 TaxID=2685869 RepID=UPI00140CC45B +--------VALEERYDARLGIFAIDTHTGETV-EHRADERFAYASTYKALAAAALLARTG +--ERRWEEVVAYDADDLVTYSPVTEQHVGTGLSLQRIAEAAVRESDNTAGNLLLDELGGP +AGFQQALRELGDDVTVAARRETALNDTAPGDRRDTSTPRALAQVLQLYAVGDALRPPARR +TLLSWMRGNATGDTLVRAGVPDGWRVADKSGAAAYGTRNDIAVIEVPGRDPVVMAVFSDR +GTPAAEYDDALVAEAARVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Klenkia brasiliensis TaxID=333142 RepID=UPI000A61D212 +-------VDALEAAYAARVGVWALDTGTGQVL-EHRADERFAHASTLKLLLVGLLLDRVP +--DAELDAVVPIGADDVLEYAPVTSQHVGTGLPLRELMAAAITVSDNTAANLLVARLGGP +AQVQAALRELGNPTTRVDRVEPDLNEALPGDPRDTSTPADLGATVQQLVLGDVLAPDRRA +LLQQWLRENTTGDAAIRAGVPEGWEVGDKTGSGGYGTRNDVAVVQPDDGAPLVVVLLTDR +GVPDADADDGLLADATRLVVDQ- +>[subseq from] class A beta-lactamase n=1 Tax=Lentzea kentuckyensis TaxID=360086 RepID=UPI000A37FDF4 +---LTGKLRELERQHNARLGVFATDTGTGRTV-LHRADELFPMCSTFKTLVAAAILRRDH +-DGTLLSKVIHYTMDDCIKYAKITEQNLANGMTVSALCEATITFSDNCAANLLLRELGGP +TAITRFSRSIGDPVTRLDRWEPELNSAEPGRTTDTTSPRAIGQSYARLTLGHALNRADAD +QLTKWLLANTTGDHRIRAGLPAAWRWGDKTGTGQYSTTNDVGIAFPPGRAPIVIAVLSTK +KDPTGGADEPLVVKTAELVAASf +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6D1LVG6_ECOLX +----------------------------NAQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAHTLRNLTLGSALGETQRA +QLVTWLKGNTTGAASIHAGLPTSWVVGDKTGSGDYGTTNDIAFIWPEGRAPLILVTYFTK +PEQKAESRR-------------- +>[subseq from] Beta-lactamase n=1 Tax=Parasphingopyxis lamellibrachiae TaxID=680125 RepID=A0A3D9FD09_9SPHN +-------LEGIERRIGGRMGVALVD-DTGTQLrSYRGDERFAMCSTFKLALSAAVLERVD +GGDMSLDDMVSFGEDDLLDYAPVARMHLADGMSVGQMAEAISTLSDNVAANLLLDAIGGP +EAMTEFFRRHGDTVSRLDRREPELNENVPGDERDTTSPSAMAGLVTRLMFEDALGEAGRE +QLAAWAVANQTGDDRIRAGMPEGWTVGDKTGSCGT-AYNDIGIVWPPSGRAFVLTVYVDR +PAAEGAEVDAAIAEIAALAA--- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=UPI00028DF5BB +--KINEDLAAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLNDMD +NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSVGGP +RGVTMFLRTIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMVWKENHKPVYISIYITG +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] Beta-lactamase n=2 Tax=Mycobacteriaceae TaxID=1762 RepID=A0A0E3XQA2_MYCCH +-----TELASLEKDFGGRVGVYALDTGSGATL-GHRANERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYTQSDLLEWAPVTSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD +LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP +EDPKSTQGKPTIAAATRIALKAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007526163 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTSLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007560E62 +--TAQSQLDALEQASNGRLGVAALDTANGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTEVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6B8JIG1_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLQSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARAGAL----- +>[subseq from] Class A beta-lactamase n=1 Tax=Blastococcus sp. TF02A-26 TaxID=2250577 RepID=A0A367A775_9ACTN +----AGELVALEEQFDARLGVYAVDTGSGRTL-AHRADERFAHASTIKALAVGALLARTS +--AADLQRSVPIERSDLAAHSPVTGTRVGAAMTLQELCDAAVRHSDNTALNLVLQELGGP +AGLDAALEAMGDDVTQVSRTEPDLNSVVPGDPRDTTTPRALANGLRAYAVGLGVDAEDRE +QLADWLRRNTTGDTLIRAGVPGDWVVGDKTGTAAYGTRNDVAVLVPPGRAPIVVAVMSSR +DQLDAAHDDALLAAAARVVVTAf +>[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=A0A3P6L894_LYSSH +------MFVQLENEFDAQLGVYAIDTETNRTV-EYQPNERFAYSSTFKPFAAAILLKQNS +--LEDLEKVVTYTNDDLVPYSPVTEKHVDTGLTLLKINEAAIRKSDNTAGNLLLEAIGGP +DKFEQALHDIGDDVTQPERYEIELNKFTPGNKRDTSTPRAMATNLKKVALSDFLTDDKRE +LLINWMTGNESGDPLIRAGAPEEWVVVDKSGAGTYGTRNDIAIVWPPNKEPIVIAIMSRH +DIENAEYDDALIAKAAEITL--- +>[subseq from] Beta-lactamase n=5 Tax=Vibrio parahaemolyticus TaxID=670 RepID=S5IYD2_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQMDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. Act143 TaxID=2200760 RepID=A0A2U3A1X4_9ACTN +-----AGLHELEAAHGARLGVFARNIATGRTV-RHRADELFPMCSLFKTLASAAVLRDLD +RDGEFLSRRIHYTDADLPKGSDKTREHLADGMTVAELAEVAITFSDNGAGNLLLRELGGP +TAVTRFARSLGDRVTRLDRWETELNSAEPWRITDTTSPYAIGRTYGRLVLGDALDGPDRD +LLTHWLRSNTTSGTRLRAGLPASWTVADKTGGGSYGTNNNVGIAWTEDGTPLLLAVLTTM +PAPDAARDDALVRDTAALLAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces ochraceiscleroticus TaxID=47761 RepID=UPI0004CC623F +---LSGQFERLEREHDARLGVFARDLATGRTV-RYRADERFPMCSVFKGLAAAAVLRDLD +HHGEFLAERIHYSKKYVTDYAPISSENVAHGMTVAELCAAAVSHSDNGAANLLLRELGGP +TAITRFCRSLGDGTTRLDRWEPQLNSAEPWRTTDTTTPRAIGTTYGRLVVGRALAAEDRK +RLKGWLIANTTNTKRFRAGLPEGWITADKTGGGSYGVANDVGVAWPPGRSPVLLSVLSTT +HAPEGPSDDALVAKTAGLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces longwoodensis TaxID=68231 RepID=A0A124HSA0_9ACTN +----GEEFRTLEQRYGARLGVYARNVRTGRTV-AHRAGERFAMCSTFKAFAAAAVLRDHA +-DCAPLDRVIHYPPRDILDNSQHSEDHLATGMTVGQACAAAIQYSDNTAGNLLLRQIGGP +QGLTRFFRSLGDRVSRLDRWETDLNTAVPGDQRDTSTPHALGTSFERLTLGRGLGRTDRE +HLVTWLKGNTTSAQRFGAGLPRDWTLADKTGTGSYATAHDIGIAWTTRHTPLLLTVLSTK +DATDAPVDNDLIRDTAALLA--- +>[subseq from] Class A beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A6B1KM47_9ACTN +------RLADLEREYGARVGVYALATGTGATA-VHRADERFAFCSVFKALAAAAVLHHRS +--LAGLDRRVTYTRADLRSTTPITAQHVATGMTLRQLCDAAVRYSDGTAGNLLMRDLGGP +AKLTAYLRGLGDTVSRMDHYEPELHDVRPKDPSDTTTPRAVATDFRKLLLGTALPAGERG +LLTDWLSHNATGARRVRAGLPKGWRVADKTGTGNYGRANDIAIVRPPRTAPLVLAVMTDR +PGYDAEPSDALIAEATART---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0005EC560D +-----ARLADLERAYGARVGVYAVATGTGVTV-VHRASERFAFCSTFKALAAAAVLHHRS +--PGGLDRRVTYTEADLRSTAPVTGKHVDTGMTLRELCDAAVRHSDGTAGNLLMRDIGGP +ARLTAYLRGLGDTVSRMDHYEPELHDVPPDDPADTTTPQAIATDFRRLLLGTALPARERR +LLMDWLSRNATGARRIRAGLPGNWKVADKTGTGNYGRANDIAIVHPPRTGPLVLAVMTDR +PGYDTEPSDALIAEATRRT---- +>[subseq from] Beta-lactamase n=5 Tax=Mycobacterium kansasii TaxID=1768 RepID=X7XTE2_MYCKA +--DLQNRFAELEHRYAARLGVYMPATGTTAAI-AYRADERFAFCSTFKALLVAAVLHQYP +--LSHLDKMVTYTSADIRSISPITQQHVATGMSIGELCDAAIRYSDGTAANLLLAEVGGT +SGFTGYLRGLGDSVSRLDQEEPELNRDPPGDERDTTTPHAIALDYQQVVLGDALPADKRA +MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPAGVSHVVAILSDR +ASYDAEWSEALVADAARCVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium kansasii TaxID=1768 RepID=UPI000CDDF961 +--DLQNRFAELEHRYAARLGVYMPATGTTAAI-AYRADERFAFCSTFKALLVAAVLHQYP +--LSHLDKMVTYTSADIRSISPITQQHVATGMSIGELCDAAIRYSDGTAANLLLAEVGGT +SGFTGYLRGLGDSVSRLDQEEPELNRDPPGDERDTTTPHAIALDYQQVVLGDALPADKRA +MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPAGVSHVVAILSDR +ASYDAEWSEALVADAARCVAE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A345N8C7_ECOLX +----------------GRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLSAGWFIADKTGAGERGARGIVALLGPNNKAERIVV----- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter cancerogenus TaxID=69218 RepID=UPI0010C15D9C +---VTDTIQTTEDHIKGRVGFTEIDFLSGKVLgSHRHEERFPMMSTFKVLLCGAVLARVD +KGLEQLERRITYNEHDLDDYSPVTRQHLADGMSVSELCNAAITTSDNTAANLLLSTIGGT +EGLTQFVRSIGDNYTRLDRHEPSLNEALPGDERDTTTPAAMAQTLRKLLNGSLLTIESQQ +KLITWMQEDKVGGPLFRSVLPVGFMIADKTGAGEHGSRGIVALLGPRGKPSRIVILYITN +THSSMNELNEHIAGIGDSIIKHw +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacteraceae bacterium TaxID=2052182 RepID=A0A522RSA4_9GAMM +---AALRLADLERVHGGRLGVAIFDTGSGRRI-ANRGDERFLMCSTFKLLLAAAVLARVD +RGEEELDRRIVFDQSALLDWAPLTKQHVGPPMTIAELCRAAITLSDNTAANLLLANIGGP +AAVTRYARSLGDPVTLLDRIEPELNPY------DMTTPSAMLGDIQKLLLGDALTPASCK +LLTHWMLDCQTGLQSLRAGLPPGWRIGDKTGQWDLGANNDIAIVWPPKRKPLLVTAYYMN +HATDPVGRKAVLAEVGRIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. MSh2 TaxID=1506588 RepID=A0A084DCN4_9BURK +--TAQAELGALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEVVSGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTTFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDALQEPQRT +QLAEWMAVGATGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptosporangium roseum TaxID=2001 RepID=UPI0004CD8DDB +--RARKELRTLEASFKGRIGAYAVDTATGKTI-TYRSGERFPLLSTFKAIAAAAVLHKAR +TDPGLLNKVVRWTTAELQGHSPVTEKHVKDGLTVARLCEAAITQSDNTAANMLLKQIGGP +AGLTAYFHTLKDPISRLDRWETELNDWSPKEKRDTTTPASMGRDLRAVTTGDALNAKDRE +RLNAWLIANKTGDARIRAGLPKTWTVGDKTGTNSYGAGNDIAVVWPGKPAPVIMSIYTNR +RAVDAAADDKVIADTAAILA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces rubidus TaxID=310780 RepID=A0A1H8PQJ4_9ACTN +--STDHAFRELEQRFHAHLGLFVLDTGSGRSV-TYGADRRFAMCSTAKVLAAGALLRQDD +--DADLARTLTYSRSDLLDHAPITSQHVDHGMPLRDVIAAALQHSDNTAENLMLRELGGP +AGLQRAVTALGDTTTHVNRTEPALNEATPGDPRDTSTARALAADLRTLLLGTALPAAHRA +RLTDWMLRNTTGGPYVRAALPKGWKAADKTGSGGHGTRNDIAVAWPPAGAPILVSVLTDR +DDPAAASDDALIATSVRTA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. LaPpAH-108 TaxID=1155714 RepID=UPI00037BE98F +--DVTARLRALEREYDARLGVYARNTRTGRTV-AYRAGEPFAMCSLFKAFAAAAVLRDHS +GAECGLDELIHFPPADILSNSEHSEDYLETGMPVRDACALAIRYSDNTAGNLMLRRIGGP +AGLTRFFRSLGDEVSRLDRWETDLNTAIPGDPRDTSTPYALGRSLERLTLGSALSAADRR +QLVAWLSGNTTSTKRFRAGLPADWTLADKTGTGSYASAHDLGIAWTTRRTPVVLTVLTTK +AEQDAPVDESLIERTARVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075875B9 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cepacia JBK9 TaxID=1395570 RepID=A0A0U3UCF1_BURCE +--AAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVAGSPVTESHVDTGLTIAQLCEAMLQAGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDRWEPELNQAAPGDERDTSTPVAMVDTLQRLLLGKTLQEPQRT +QLTEWMAGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +QQADAAVRADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio rotiferianus TaxID=190895 RepID=A0A2K7SPC6_9VIBR +--KLNEDLAAIEQHIGGRIGVSVWDTQNDEHW-DYRGDERFPMMSTFKTLACATMLSDMD +SEKLDKNATAKVEERNIVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +NGVTRFLRSIGDGATRLDRFEPRLNEAKPGDKQDTTTPNAIVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPIYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00092C017A +-----NELVSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL +SEPGLLDQRIQYTQSDVLEWAPITSQHVSNGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium asiaticum TaxID=1790 RepID=A0A1A3CTT7_MYCAS +---LFHQFEQLERRYEGRLGVYVPE----PAI-AYRADERFAFCSTFKAPLAAAVLHRYP +--LDHLDKLVSYTRSDINSVSPVTEQHVDTGMTVRQLCDAAVRYSDGTAANLLLAEIGGP +AGFTAYLRSLGDNVSRLDQLEPELNRDAPDDQRDTTTPHAIAPVFQQLLLGDALPPDKRA +LLGDWMARNTTGGKRIRAAFPPDWKVADKTGSGDYGRTNDVAVVWSPSGAPHVIAIYSDF +VGYDAQPNEAFVADAARIVAA-- +>[subseq from] Beta-lactamase n=2 Tax=Vibrio harveyi TaxID=669 RepID=A0A3A1PWM2_VIBHA +--KINEDLAAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLNDMD +NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSVGGP +RGVTMFLRTIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITG +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] Beta-lactamase n=1 Tax=bacterium AM6 TaxID=1954209 RepID=A0A244C097_9BACT +-----ADFAELEKACGGRLGVTVLDSRTGRRIgGHRQGERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVAVAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVTGGP +AALTAFLRDHGDRVTRNDRYEPDMNRFAAGDPRDTTSPAAMAASLALFAVGDGISAASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG +ASVDDEQRAAVLAQVGRIA---- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A104J0E0_9BURK +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] UPI001442C1CD UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI001442C1CD +--ATSRAFAALERTHGATLGVTAVDTGNGRAV-GYRSGERFPFASSNKTFIAAATLQRTT +--TADLGTVIHYTRADLLDYAPITSRFVDTGMTVRELLDAMLRFSDNTAANLLVARLGGP +DAVEQWMRGIGDRVTNVDRVEPDLNEALPGDPRDTTTPAQFAADLRTVVLGKTLEAADRT +LLRNTMLDNTTGDETIRAGVDPAWPVADKTGTGEYGVRDDIAVVYPAGRAPVIVVVLTRK +DTPDATPDNALVAEAAKVAVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Psychrilyobacter atlanticus TaxID=271091 RepID=UPI000426D91E +-----KEITAVEKRLGANVGVAVYDTKDHRIS-EYNGDKRFPLMSTFKTLAAANILYKTD +QRLLSLEKKISIHEDEILSYAPVTKEFVGETMKLNEVCSAAMSMSDNTAANIMLENLGGP +QELTKFLREIGDTTTRIDRIEPELNEALKGDERDTTTPKAIVKTLNKLLYGKVLSNTSKE +QLKKWMMDNKVADNLFRAVLPKKYLIADRSGAGGYGSRGITAVVWSEDRTPIIISVYLTQ +TDATFVERNEAIVQIGDVIFNEy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces gougerotii TaxID=53448 RepID=A0A6A0CPY6_9ACTN +---AVRRLAGLERASGARLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RDGEFLSRRIFYTAKDVERGAPETGKNLANGMTVEELCEVSITASDNCAANLVLRELGGP +TAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITGTYGRLVLGDALNPRDCR +LLTGWLLANTTSGGRFRAGLPKEWTLGDKTGAGRHGTNNDAGVTWPPGRSPIVLTVLTTQ +PEEDAVRDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=2 Tax=Citrobacter koseri TaxID=545 RepID=Q9AL74_CITKO +---------QEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD +RKALALSASTQFESSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP +QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE +QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ +TPATMAQRDAAIVRIGESLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus ligniniphilus TaxID=1134413 RepID=UPI0009DA7B5C +---TIEKFEQLEKQYDARLGVYAIDTGTKETV-EFREDERFAYTSTSKALAAAILLKQNP +--ISVLEEIRTFTNEDIVTYSPITEDFVDKGMSLGKIAEAAMQYSDNTAGNLLFEELGGP +DGFEKALRESGDTITMADRIEPDLNEAIPGDLRDTSTPKALAINLEVFGISEYLPADKQE +IFTNWLKGNTTGDSLIRAGVPEGWEVGDKSGAGGYGTRNDIGIVWPPNREPIIIAIMSSR +NEENASFNDELIAKATKVIVQAf +>[subseq from] Beta-lactamase n=1 Tax=Agreia sp. Leaf283 TaxID=1736321 RepID=A0A0S9PIA5_9MICO +------AFAQLEQEFDARLGVYALDPLSRAEV-AYRADERFAYASTFKALAAGILLKTVP +--DEQLDELVSYGADELLPNSPVTEANVNEGMTLRAVAEAAVRFSDNTAGNIVLERLGGP +EGFTQALRDLGDTTSSSDRIETDLNSAIPGDTRDTSTPRAFALDLATLLTTDALGAAQQS +QLIDWMTGNATGSELIAAGLDAGWSVADKSGAGAYGTRNDIALVWPPSGSPIVLVIMSNR +PTEDAEYDNALIARATEAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces triticagri TaxID=2293568 RepID=A0A372M6K9_9ACTN +--ELSEQFRELEKRHAARLGVFARDTATGRTV-HYRADERFPMCSVFKSLAAAAVLRDLD +HDGGFLARRIHYTRDCVDTYAPVTGRNLERGLTVGELCAAAVSESDNAAANLLLRELGGP +TAVTRFCRSLGDRVTRLDRWEPELNSAEPWRRTDTTSPRAIGSTYARLVLGRALDEPDRR +RLTRWLIANTTNTERFRAGLPADWILADKTGGGDYGIANDVGVVRPPHGAPLVLSVLSTK +LDPAGPTDNPLVARAAGLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 2112.5 TaxID=1907386 RepID=A0A419V9Q0_9ACTN +---LAAQLRDLEQQYSARLGVFARDTATGRTV-KYRADERFPMCSVFKTLAAAAVLRDRD +--DDFLGHRIRYTEKYVTDYAPITSKNLANGMTVGELCAAAVSYSDNGAGNLLLGELGGP +AAVTGFCRSIGDGTTRLDRWEPDLNSAEPWRKTDITSPRAIGQTYARLVLGSTLTTADRT +RLTRWLVANTTNGERFRAGLPADWTLADKTGGGQYGVANDVGIVWPPGRPPLVLSVLSTK +FDPEGPTDNPLVAKAAALVA--- +>[subseq from] Beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=A0A2I7K758_9RHOB +--DLAETIHSWETALDARLGVFLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD +RGTEDLTAQIEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP +EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTATPRSVLSTLHAALSGTMLSGSSSA +QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE +TNADFSRRNQAISDIGRAMI--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI00080F3FC5 +-sQLNEDISLIEQQTSSRVGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLIAQISQLILQKy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F13E3 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +KLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +AGADASPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Jiangella anatolica TaxID=2670374 RepID=A0A2W2AXQ3_9ACTN +----DPDVDELERAHDVTLGVSAANLATGARL-AHRDGDRFPILSVFKSLAAAAVLRDLD +--EDRLAHRVWYPPADVLANSSVTAERVGTGMTVAELCDAAIRFSDNAAGNLLLREIGGP +RGLTTFARSIGDRATRLDRWETELNSAVPGDERDTSTPAALARAFAGLLAGDLLRPRDRR +RLRDWMLANTTSGARFRAGLPADWRLADKTGGGDYGTNNDAGVAWNPAGEPIVIVAMSRR +AEKDAPRVDAALADVARLVAR-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio TaxID=662 RepID=UPI00062E5371 +-sQLNEDISLIEQQTSSRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLIAQISQLILQKy +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. ARG-1 TaxID=1692501 RepID=A0A0L6J657_9RHIZ +---ADPALAAIEKRLGGRLGVSAG-TQERVFL-RHRADELFPMCSTFKVLAAACVLARVD +AGSESLARLVTYGNDALLSYAPVIRKGLEAGMTIADLCAAALEWSDNSAANLLLTALGGP +EALTLWLRGIGDTVTRLDRNEPTLNTALQGDPRDTTSPEAMRATLARLLLGPSLSAASRA +RLEAWMVASQTGFKRLRAGLPSDWTVGDKTGTGDNGTVNDVAILRPPGRAPILACVYVTG +AQAPTEVVEAAHAEIGRLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces albus subsp. albus TaxID=67257 RepID=A0A0X7JDW7_9ACTN +-----RRLRALEREHQARVGVFALNLATGATL-LHRAHELFPICSVFKTLAAAAVLRDLD +HDGTQLSRVIHYTGADVTKHAPVTKDHIDTGMTIRALCDATIRYSDNCAGNLLLRELGGP +TAITRFCRSLGDPVTRLDRWEPELNSAEPDRRTDTTAPYAIARTYQRLVLGNALDRPDRA +LLTDWLLRNTTSVERFRKGLPKDWKVADKSGGGSYGTSNDVAIAWTPDGAPIVLALFTHK +PTQPTASGDPLVIEA-------- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI0007E9B0EB +---IDDQIAELERRHHALIGLYAANLDTGRTL-THRPDETFAMCSTFKGYAVARVLQMAE +RGEISLDNRMFVDADALVPNSPVTETRVGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPGGQRLLLVMMTRS +QGPKAENLRPLIGELTALV---- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A2N9CVI9_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMIGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID7909 TaxID=2706092 RepID=A0A6B2ZMX2_9ACTN +---TTARLRELERTHGARVGAFAYNVATGVTV-RHRADERFPMLSTFKTLAAAAVLRDLD +RDGEVLEKVIHYTEADCVSDSPVTDTHIASGLSVARLCDAAIGDSDNTAGNLLLRELGGP +QAVTRFARSLGDRVTRLDRWEPVLNSAEPGRVTDTTTPSALARDYARLVLGNALEPRDRE +RLTYWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYASCNDVGVAWTPEGVPVVLAVLTTK +PASDAAGDHPLVRDAAEALA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium szulgai TaxID=1787 RepID=A0A1X2EH11_MYCSZ +--DLTSRFMELERKYTARLGVFAAATDPSAEI-AYRADERFAFCSTFKAPLVGAVLHQYP +--LTHLDKVITYNSDDIRSISPVTQQHVQTGMTIRELCDAAIRYSDGTAANLLLADIGGT +AAFTGYLRELGDNVSRLDQLEPELNRDAPDDPRDTTTPHAIALVFQQLILGDALPPEKKT +MLTDWLARSTTGAKRIRAGFPAEWKVVDKTGSGDYGRANDVAVVWSPSGAAHVVAIYSDR +AGYDAEPSDAIIAEAAAAIAK-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacteroides salmoniphilum TaxID=404941 RepID=A0A4R8S9H4_9MYCO +-----TELASLEKDFGGRIGVYALDTGSGATL-GHRPNERFLMCSTVKTFIVSAILHRSL +SEPGLLDKRIQYTQSDIMEWAPVASRHIAEGMTVSELCDATIRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEEQLN--VPDGDLDTSTPLQLVTNLRRLVLDEGLDSQGRD +LLTDWLKRNTTGDQSIRAGVPAGWTVADKTGSGFKGETNDIAVIWPPGRAPIVVAVLTVP +DDPKSTQGKPTIAAATRIALKAf +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium setense TaxID=431269 RepID=A0A1A0PTS7_9MYCO +---IDDQIAELERRDNALIGLYATNLDSGRTI-THRPDEMFAMCSTFKGYAAARVLQMVG +RKQISLDNRVFVDPDAIVEYSPVTEPRAGGEMTLGELCRAALQQSDNTAGNLLLKTIDGP +PGITAFARSIGDQRTRLDRWETELNSAIPGDPRDTSTPAALAGGYREILAGDALSPPQRR +QLQDWMRANET--SSVRAGLPEGWTTADKTGSGDFGSTNDVGIAYGPDGQQLLLAVMTRS +QADDPKADNPLIGELA------- +>[subseq from] Beta-lactamase n=1 Tax=Rubidibacter lacunae KORDI 51-2 TaxID=582515 RepID=U5DDY1_9CHRO +--DLIAAVQQIEARLNARIGIAVIDKETDRNW-RYHAGDRFPINSTYKTIACAALLSRVD +SGQEQLDRIVIFDESQLADYSPVTETRVGAPMSLGELCQATIATSDNSAANFVMQAIGGP +QAVTQFMRSIGDRTSRLDRWSPELSESVPGDQRDTTSPNAMAMMLEQLVLKGTLSFESRQ +TLESWLKGNEISGDLIRAAVPSDWDVIDKTGSGGYGSRSIAAVMWPPQREPVIAAIYITE +TEVSFAERNAAIAEIGEAIV--- +>[subseq from] Beta-lactamase (Fragment) n=5 Tax=unclassified Rahnella TaxID=2635087 RepID=D7PIH7_9GAMM +-----------------------------SQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLNRRVSLTKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP +RKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PQKDAK----------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. MBT76 TaxID=1488406 RepID=UPI0009A012D8 +--RVSRQLRELEREHSARLGVFARNMATGRTV-VHRAGERFPMCSTFKTLAVAAVLRDLD +HDGTFLAKRIHYTADYAKAYDKITGKNVANGMTVEELCGAAISYSDNAAANLLLTELGGP +TAVTRFCRSVGDGTTRLDRWEPDLNSAEPDRITDTTTPRAIGRTYAQLVLGNALDPADRK +RLTGWLLANTTSDQKFRAGFK-GWTVADKTGSGSYGTSNDVGVVWTPKGSPVVVSVLTTK +HEPKAAGDDALVRKAAELL---- +>[subseq from] class A beta-lactamase n=1 Tax=Devosia submarina TaxID=1173082 RepID=UPI000D350737 +----VEVAAALEEKLDARIGLTVYDLDNQNTW-DYRADERFPMASTFKAMACAALLSRGE +---TVMNTAVEIAASDLVTYSPVTEALVGQSVPASELCDATMRTSDNTAANKVLQVLGGP +EAVTQFLQTIGDVTTRLDRWEPDLNQGTPGDLRDTTTPKAIARSLHDLVLGNKLDGVARK +QFTAWLLSNKVGDPLLRAGIPPDWRIADRTGAGGHGTRGIIAVMWPPNRAPLVAAIYITE +TAASMEERNTAIAEIGAALA--- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A0H2XWP9_BURCA +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMAGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhodococcus TaxID=192944 RepID=UPI000BE396EE +--SLDTKLDALEARYSTRIGVTAIDPATGQIY-QHRGDERFALCSTFKTYAAAEVLRRTR +AGTSSLDKPVLVEPGDLVENSPVTAAAVGTPMTLRQIAEAALTRSDNTAGNYLLEEIGGP +PAITSLAREIGDESTRLDRWETELNSALRGDPRDTSTPKELADGYQALLLGDALRSPERA +QLVDWMRASKTSDKRIRAGLPDGWTAAAKSGAGRFGTVNDAGVAWDRDGNPLVLAILTDS +LTEDAQGNNQVVADTTAAVVE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudonocardia sp. SCN 73-27 TaxID=1660132 RepID=A0A1E4P5Q9_9PSEU +-------FDDLEARFGARLGLWARDTGSGAEV-AHRADERFAFCSTFTMLAAAAVLRDVA +--PDRLDAVVHWSPADLMASARITRARVTTGMTLRELCDAAVRFSDGTAGNLLMREVGGP +AGLTAFARGIGDDVTRVDRSEPDLAQGAPGDERDTSSPRASGQDMQRVVLGDALAPDRRE +LLQDLLVRNTTGDARVRAGVPEGWRVADKTGTGGYGTANDVAVVWPPGRAPIVVALMSTK +AQRYADVDEALLAEAAGRVATAf +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MR_MD2014 TaxID=1561023 RepID=A0A0N7A303_9MICO +--ATSRAFAALEERDDARIGVVAIDTADGSSV-GYRADERFAFASTNKAFIAAAVLDASS +--GEDLDEVVHYGRGDLLEYAPVTRRYVDEGMTLRALVDAAVRESDNTAANLLVERLGGV +GGVSRWLRGIGDDVTRVDRVEPDLNTAVPGDQRDTTTPAQSASDLRAVLVGDALDAGDRE +LLRSSMAGTTTGDGTIRAGVPGGWSVADKTGTASYGVRNDIAVVRPPGRDPVVLVVFTAH +ERADAEPSDALVAAATRLAVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=A0A2L2KDY8_9VIBR +-sQLNEDISLIEQQTSSRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLIAQISQLILQKy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI000758B4F7 +--AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPERA +QLTEWMTGGARSATGIAAGVPPGWRIADKIGSGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATSAf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces rimosus subsp. rimosus TaxID=132474 RepID=A0A0M8R2P9_STRRM +----VRRLRALEREHQARIGVFALNLATGASL-LHRAHERFPMCSVFKTLAAAAVLRDLD +HDGSQLSRVIRYTEADVTKHAPVTKDHIGTGMTIRDLCDATIRYSDNCAANLLLRELGGP +TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA +LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDGAPVLLTALTHK +PTPTAPGDTPLIIKLATV----- +>[subseq from] Beta-lactamase n=1 Tax=Alcanivorax sp. KX64203 TaxID=1817793 RepID=A0A154C5J6_9GAMM +--ALGHRCQEWERRHGGRIGVAVWNLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD +QGQESLDRRLLVSRKDLVGWSPVTGKRTGEGMTVAELCEAAVAWSDNGAANLLIKSFGGP +GALTDFLRESGDPVTRLDRLEPELNGYGPDGEYDTTSPAAMLETLHRLLFGEVLSAHGRA +QLAAWMIANKTGDRRLRAGFPANWLVADKTGTSGLGYSNDVGVAWSPARGAVLVTVYCEM +PKAEAGIRDRIIAEVAETV---- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas acidaminiphila TaxID=128780 RepID=A0A2L0SJV6_9GAMM +-------FDALEAESGGRLGVCLWHPASGARF-GQRMDERFPMCSTFKFLLVAAVLHRAA +QGRLSLDRRVAVRASDLIAHSPVSARHVDKDLGVRDLCRATLTTSDNAAANLLLPLVDGP +AGLTAFLRAQGDAVTVAARYEPDANRFAPDDPRDTTSPAAMAGNLQRFVFGQALDAASRQ +QLADWLIDNQTGDARLRAGLPAGWRVGDKTGSNGRDTSNDIAVLWPRGGSPWVLTVFLQG +SVLDDAGRDAILRRVGEQATT-- +>[subseq from] Beta-lactamase n=1 Tax=Jiangella anatolica TaxID=2670374 RepID=A0A2W2B817_9ACTN +--AVAAALTALEADYQARLGVYAIDTGTGQIV-EHRADERFAFASTHKMLSAAAVLQATE +--PADLEQLVPIDAAEVVGWSPVTEPAAGAGLTLLEIIQAAITVSDNTAANLLFEQLGGP +DGLEAAVRGFGDATTSFDRIEPDLSEWAPGETRDTTTPRAMAANVEGLLLGDLLADEDRA +LLHDTMRANTTGDELIRAGVPAGWLVADKTGSATHGGRNDVAVIEPPGAAPIVLAVYSNR +LDPDAESDPALIAAATAIVVDE- +>[subseq from] ClassA n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T426_9BACT +--ALNQTLAELERVSRGRLGVTLLDTGNGQTS-SYRGDERFLMLSSFKTLAAAYVLARSD +KGEDQLNRRVPITEADLLDYAPITRLHIGQQMTLAELCHATITTSDNTAANLILRSYGGP +QALTRFLRSLGDNVTRHDRYEPALNQMSPVEPMDTTSPNAMSNTLNTLLFGTALKSESRQ +LLWSWLVANTTGDRRLRASVPSDWIVGEKTGTARI-GANDVGFLQAPGSSAVIVSVYLET +DALAAPERDQIIAEVGRRVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Oceanicella sp. SM1341 TaxID=1548889 RepID=UPI000E48A7CB +--RLDDTVRRIEQSLGARVGLMVRDTGSRREW-SHRAAERFAMNSTMKVPLCAAVLHAAE +AGALDLDTPLDIAQEDMLEYAPVAARHVGGSLPVRDLCLAALDMSDNTATNLLIDHLGGP +QEITAFLRGIGDEASRADRREPGLNDVPPGDERDTTTPQAMAGTLEALLLGEALGAGARE +QLLAWMTPGSVTGKLMRAAVPEGWVVADKSGSGST-TRNLVGLVMPPARAPVVFAIFLSG +AEADFATRDKAVAEISAAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio campbellii (strain ATCC BAA-1116 / BB120) TaxID=338187 RepID=A7N8N9_VIBCB +--KLNEDISAIEEHISGRIGVSVWNTQTDDHW-DYRGDERFPMMSTFKTLACATMLSDMD +NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEATMLMSDNTAANIVLRSIGGP +RGVTTFLRSVGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPIYISIYITE +TDLSLQARDQIIAQVSQLILDEy +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis balhimycina DSM 5908 TaxID=1081091 RepID=A0A428WDT2_AMYBA +----QPDFAPLERDFDARLGVYAVDTGTGREL-AHRADERFGYASTHKAFSAAAVLQRTS +--IEGLAKVLTYTRADVPANSPVGEKHVESGLSLRDAIDAALRYSDNTAANLLFRELGGP +AGLAAALRGIGDTITHVDRIEPGLNDLAPGDIRDTSTPHAMAADLRAFTLGTALPPEQRA +LLTDTMRANLTGGALIRAGTPAGWAVADKTGTGEYATRNDIAVVRPPGRAPIVLVVMSDR +KTEDAGHDDRLIAQAAGLALDSf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 2224.1 TaxID=1881020 RepID=UPI00089D883A +---LAAQLRDLEQQYSARLGVFARDTATGRTV-KYRADERFPMCSVFKTLAAAAVLRDRD +--DDFLGHRIRYTEKYVTDYAPITGKNLANGMTVGELCAAAVSYSDNGAGNLLLGELGGP +AAVTGFCRSIGDGTTRLDRWEPDLNSAEPWRKTDITSPRAIGQTYARLVLGSTLTTADRT +RLTRWLVANTTNGERFRAGLPADWTLADKTGGGQYGVANDVGIVWPPGRPPLVLSVLSTK +FDPEGPTDNPLVAKAAALVA--- +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Rahnella TaxID=34037 RepID=D7PII7_9GAMM +-----------------------------SQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP +RKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PQKDAK----------------- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Tr-862 TaxID=2608331 RepID=UPI001419BBBE +--AAQAELAALEKASNGRLGVAVLDTSNGTRI-AHHARERFPVCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTVFRLDRWEPELNQAAPGDERDTSTPVAMVDMLQLLLLGDTLREPQRA +QLTEWMTGGTRGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PSADAAARADVVASAARIAT--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces recifensis TaxID=67355 RepID=UPI000A3CE885 +-----PELAALEKRYGARLGVYAHNTRTGATV-AYRADEPFAMCSTFKAIAAAAVLRDHG +-GRTALGEVIHYPPADILSNSEQSKAHQQTGMALGDVCAAAIQYSDNTAGNLMLRRIGGP +AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPRALGRTFELLTLGRALSDGDRG +QLVGWLRGNTTSGKRFGAGLPSDWVLADKTGTGSYATANDLGVAWTGKGTLLLLSVLSTK +PAPDAPVDEALIEETARLLA--- +>[subseq from] Beta-lactamase n=3 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A2X1I0P0_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGA +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella sp. 348-Celery TaxID=678975 RepID=D7PIJ7_9GAMM +-----------------------------SQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLNRRVSLTKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP +RKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PEKDAK----------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseoflavus TaxID=35619 RepID=A0A0L8MSV8_9ACTN +-----RRLRALEREHQARVGVFALNLATGATL-LHRAHELFPICSVFKTLAAAAVLRDLD +HDGTQLSRVIHYTGADVTKHAPVTKDHIDTGMTIRALCDATIRYSDNCAGNLLLRELGGP +TAITRFCRSLGDPVTRLDRWEPELNSAEPDRRTDTTAPYAIARTYQRLVLGNALDRPDRA +LLTDWLLRNTTSVERFRKGLPKDWKVADKSGGGSYGTSNDVAIAWTPDGAPIVLALFTHK +PTQPTASGD-------------- +>[subseq from] class A beta-lactamase n=1 Tax=Gordonia sp. NBRC 107697 TaxID=2589738 RepID=UPI00137B2DD2 +--QVHDEFARLEDRYGARIGVHAVDVGTSAVV-AHRPGETFAMCSTFKTYAAARVLQLVD +AGEADLNREIPIVPDDIVVNSPVTSQAVGQTMSLRDVCAAALERSDNTAGNLMLRLIGGP +AAVTCFARGIGDDASRLDRWEPELNTAEPMDHRDTTTPRALGAGYRRLLVGDVLPPAQRT +QLLDWMRANTTSAKRFRAGLPAGWTSADKSGAGDYGSTNDAGLLIGPTGQRVLAVVLVRS +RGPDAAPFNEAIAESTRLVLTH- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075C3ED3 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKIGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVIAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MR_MD2014 TaxID=1561023 RepID=UPI0009DE058D +--ATSRAFAALEERDDARIGVVAIDTADGSSV-GYRADERFAFASTNKAFIAAAVLDASS +--GEDLDEVVHYGRGDLLEYAPVTRRYVDEGMTLRALVDAAVRESDNTAANLLVERLGGV +GGVSRWLRGIGDDVTRVDRVEPDLNTAVPGDQRDTTTPAQSASDLRAVLVGDALDAGDRE +LLRSSMAGTTTGDGTIRAGVPGGWSVADKTGTASYGVRNDIAVVRPPGRDPVVLVVFTAH +ERADAEPSDALVAAATRLAVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces laurentii TaxID=39478 RepID=A0A169PSU3_STRLU +-----RALAALDREHAARLGVFARNMVTGAQV-SYRAGEPFPICSVHKVVTAAAVLRDLD +RDGEFLARRVRYSHQDVADYGPVTGEHIADGMTIAELCAATLQYSDNAADNLLLRELGGP +TAITRFCRSLGDRVTRLDRWEPALNSAEPGRVTDTTSPAAFAYTLTGLLLGEVLTPRDRH +RLTAWMRGNTTGTARLRAGLPPDWTLADKTGTGDYGTTNDAGVAWTADGTPVVLSVLSTR +PHPDAAADELLLARTATLLA--- +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Stenotrophomonas TaxID=40323 RepID=A0A4Y5QB88_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD +AGRVSLDTRVPIAAKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. Root1240 TaxID=1736437 RepID=A0A0Q7AAV4_9RHIZ +----TAAARHMERQLGGRLGLMVVDTQTDRHW-AYRADERFAMASTFKALACAALLDAG- +--EAVQGRSMTIDAKDLQTYSPVTGKKVGTAMTAAELCAVTLATSDNTAANLVLEALGGP +KRVTAFLRSAGDMVTRLDRTEPTLNEAKPGDPRDTTTAQAMVTTIGDLLLGDTLSADARG +RLTAWMEANAVADGLLRAGVPKDWRIADRTGAGGHGTRGIVAVMWPPGRLPVVAAIYVTE +TEASMATRDAAIAEIGRVIAA-- +>[subseq from] class A beta-lactamase n=2 Tax=Streptomyces rubidus TaxID=310780 RepID=UPI0009A0C00D +--STDHAFRELEQRFHAHLGLFVLDTGSGRSV-TYGADRRFAMCSTAKVLAAGALLRQDD +--DADLARTLTYSRSDLLDHAPITSQHVDHGMPLRDVIAAALQHSDNTAENLMLRELGGP +AGLQRAVTALGDTTTHVNRTEPALNEATPGDPRDTSTARALAADLRTLLLGTALPAAHRA +RLTDWMLRNTTGGPYVRAALPKGWKAADKTGSGGHGTRNDIAVAWPPAGAPILVSVLTDR +DDPAAASDDALIATSVRTA---- +>[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas acidaminiphila TaxID=128780 RepID=UPI0013759E37 +-------FDALEAESGGRLGVCLWHPASGARF-GQRMDERFPMCSTFKFLLVAAVLHRAA +QGRLSLDRRVAVRASDLIAHSPVSARHVDKDLGVRDLCRATLTTSDNAAANLLLPLVDGP +AGLTAFLRAQGDAVTVAARYEPDANRFAPDDPRDTTSPAAMAGNLQRFVFGHALDAASRR +QLADWLIDNQTGDARLRAGLPAGWRVGDKTGSNGRDTSNDIAVLWPRGGSPWVLAVFLQG +SVLDDAGRDALLRRVGEQAAT-- +>[subseq from] class A beta-lactamase n=1 Tax=Luteimonas huabeiensis TaxID=1244513 RepID=UPI000465C107 +----ATDLAALEAASGGRLGVALLRAGDGAPRlAHREGERFPMASTFKFLLAAAVLARAD +AGALSLDRRLPVRAADLLAHAPATGRHVGRDLTVRDLCRGTMVWSDNPAANLLLPLVGGP +EGLTAFLREHGDAVTECARYEPEVNRFAPGDPRDTSTPAAMAANLQRFALGDALAPASRA +QLADWLIDNRTGDGRIRAGVPTDWRVGDKTGGTR-GVSNDIALLWPPGGTPWLLACYLQG +SPLPAEARDDVLRRAAELAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces niger TaxID=66373 RepID=UPI000ABCC053 +---VTEQFRALERQYEARLGVFARNMATGRTV-RYRAAERFPMCSVFKGLAAAAVLRDLD +RDGEFLARRIHYTRADVEKHTPVTGKNLAHGMTVEALCAATVGESDNAAANLLLRELGGP +TAITRFCRSVGDGTTRLDRWEPELNSAEPWRRTDTTSPQAVGTTYARLLLGRVLTAPDRE +RLTGWLVANTTNTERFRAGLPADWVLADKTGGGDYGVANDVGVVWPPHGAPLALSVLSTT +YDPAGPAKNPLVAKVAELVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB93_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD +AGRVSLDTRVPIAAKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia latens TaxID=488446 RepID=UPI0012453F88 +---AQTELAALEKASNGRLGVAALDTSTGTRI-AHRARERFPLCGTYAVVAAAAILARGT +LDASLLPRRVLYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTSFAHDSGDTTFRLDHWEPELNRAAPGDERDTSTPVAMADTLQRLLLGDTLREPQRA +QLIEWMAGGARGAAGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIAT--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 04182 TaxID=2203198 RepID=A0A429FIY0_9PSEU +-----ADFEQLERTYRARLGVYAIDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP +--VAELDRTVTYERKDLVVNSPVTEKHVATGMPLRAVLDATLRYSDNTGGNLLFRELGGP +EGLNAVLRGIGDTTSHADRIEPELNDTAPGDTRDTSTPRALAVSLRAFALGDALPEDKRK +ILVDMMRASTTGDQNIRAGVP-GRPVADKTGTASYGTRNDIGVVWPPNRAPIVLSVLTDR +SEKDAKIDNKLLADATAAAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0005DE2254 +-----NELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL +SEPGLLDRRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAAIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAATRIVLRAf +>[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=UPI00040C59E3 +--DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD +RGTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCEAAITRSDNTAANLILERIGGP +EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTATPRSVLSTLHAALSGTMLSGSSSA +QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE +TDADFSRRNQAISDIGRAMI--- +>[subseq from] Beta-lactamase n=1 Tax=Lentzea waywayandensis TaxID=84724 RepID=A0A1I6FI35_9PSEU +------ALFELEKKFDARLGVYAMS-DNGSTI-EHRADERFAFCSTFKGLAAAAVLHRNP +--MSHLDTVVTYTEADLMKSSTITRQHVRTGMKLRDLCDAAVRYSDGTAGNLLLRDAGGP +AELTKYLRGLDDTETRMDRIEPGLTSAVPGDPRDTATPRSLGTDYQRIVLGDALEPEKRD +FLRDLLERSTTGAKRVRAGVPQGCRVANKTGTGEYGTVNDIAVVWPPNREPVLIAIMSSK +SAADAKYDEALVAEAAAYVLK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. IB201691-2A2 TaxID=2561920 RepID=A0A550HLV3_9ACTN +--SLSGQLSDLEREYSARLGIFAHDTATGRTV-AHRADERFPMCSVFKGLTAAAVLRDLD +RDGEFLARRIRYTKEYVTAYAPITDENVANGLTVEELCSAAVSESDNGAANLLLRELGGP +TAITRFSRSTGDRITRLDRWEPELNSAEPWRKADTTSPRAIGQTYARLVIGRALPSEDRE +RLTGWLIANTTNTERFRAGLPSDWILADKTGGGSYGVANDVGVVWPPGRPPLVLAVLSTK +YAADGPTENPLVARAAALVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis xinjiangensis TaxID=124285 RepID=UPI00034CAE93 +----EEAFTGLEEEYDARLGVYALDTGTGQEV-EYGADDRFAYASTFKALAVGALLDQHG +--AEVLDERMDLSEEDLLEYAPIAEEFLGEGMTLREASDATVRYSDNTAGNLVLERLGGP +EGFQEALREIGDDTTNADRWEPDLNEAVPGDERDTSTPRAMAQSLHTYVEKETLAEDERE +FLTDLLVRNTTGDDLIRAGVPQDWEVGDKSGGGRYATRNDIAVAWPPESDPVVIAVMSSR +EEEEAEYDDALVAEATEAAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces varsoviensis TaxID=67373 RepID=A0A0L8QR53_9ACTN +--DLSRQLRALETEYKARLGVYALDTATGATV-SYRAAERFPMCSVFKVLTAAAVLRDLD +RDGEFLAKRIRYTEKIVKKYTPVTGKNIANGLTVEQLCAAAVSESDNGAANLLLRELGGP +TAITRFCRSIGDKTTRLDRWEPELNSAEPWRETDITTPGDIGKTFARLIVGRALPSEDRK +RLTGWLVANTTDGERFRAGLPADWILADKTGGGQYGVANDVGVVWPPKRSPLVLSVLSTK +YDPKGPTDNPLVARTAALVADH- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium komanii TaxID=1566885 RepID=UPI000B12AAF0 +--QLGDRLGEMERSHNALIGVFAVNLDTGRTV-AHRAQDPFSMCSTFKTYAAARVLQKAE +RGELALTDRVTVEQSDIVPNSPVTGEHAGQTMTLAELCEAALQQSDNAAGNLLLRTIGGP +SGVTDFARSIGDQRTRLDRWEIELNAAVPGDPRDTTTPEAIGGGYRSLITGNVLGEPQRR +QLDDWMRANRT--SSVRPVLPPGWTIADKTGSGDYASTNDVGVAFGPAGERLLLAIMTRT +AAADVPNDRQMVGEVGSMLVA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus lehensis TaxID=300825 RepID=A0A4Y7WMI7_9BACI +-----AVFSVLEDHYDARLGVYALDTGNGQTI-AYNEDERFAYASTHKALAVGVLLQQLC +--LDELDTQILFSEADLVTYSPVTEQHVETGMSLHEISDASIRYSDNTAANLIFNEIGGP +SGFKEALREIGDEVTEPERMETELNDVKPGETRDTSTAKALAESLYAFSLGDALDEEKQT +LLNDWLIHNTTGEALIRSGVPKGWLVGDKTGSASYGTRNDIGIIWPPDEDPIVIAVLSSK +EQADAESDDALIADATEAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI000C25A439 +-----DELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL +SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP +EDPTSTKGKPTIAAAARIVLRAf +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis acidiphila TaxID=715473 RepID=A0A558A8C9_9PSEU +-------FAALEKQFGGRLGVAALDTGSGATT-GYRAGERFLMCSTVKALLVAAVLQRSS +ADPALLDRRIRYTRADLIAHSPVTASRLADGMTVAELCEAALTVSDNAAENLLSAQFGGP +AAVTAFLRALGDPLTSSDRTEPALNDSALGDLRDTTTPSWFVRDLQRVALGTALTEGQRG +RLTGWMTACTTGAAQIRAGVPAGWQVADKTGSGSAGESNDVGIVRPPGRAPIVLAIFTAP +ASKDDTTGNPTIAAATRIAL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=A0A2Z5N140_BURPY +--AAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYDVVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDMLQRLLLGDALREPQRA +QLTEWLVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPLVMAVSFTQ +PQADAAARADVVASAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. GV104 TaxID=2135679 RepID=A0A2T5XA81_9RHIZ +---AGAALARIARDIGGRVGIAVLDTGGGPAL-LHDAEGTFPLCSTFKLPLAAAILARVE +AGRERLDRRLAYGEADLDSYAPVTTRALRAGMSVEALCAAALVWSDNTAANLLLGALGGP +AALTAWCRALGDPATRLDRTEPDLNSAVPGDPRDTTRPAAMAATVETILLGPSLTEAGRA +RLEGWMTASRTGTKRLRAGLPADWGVGDKTGSGAYGTANVVALLRPPARAPLVAAVYLTG +SEATSEARDAAHAAIGRVIATIy +>[subseq from] Beta-lactamase (Fragment) n=4 Tax=unclassified Rahnella TaxID=2635087 RepID=D7PIK8_9GAMM +-----------------------------SQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP +RKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PEKDAK----------------- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase FRI-6 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A451ENM0_ENTCL +-----EQMRELETSFGGRIGVYILNTKNGKEF-SYRQDERFPLCSSFKAFLAASVLKRTQ +DKSVSLDDMMEYSGRVMEKHSPVSEKYRETGASVQTLAKAAIQYSDNGASNLLMERIGGP +EGLTAFMRSTGDTDFRLDRWELELNSAIPGDERDTSTPKAVAMSLNNIAFGSVLDAKNKS +LLQDWLKGNTTGNARIRAAVPDKWVVGDKTGTCGYGTANDIAILWPDANSPAVMAVYTTR +PNQNDKHDETVIKNAAKIAIN-- +>[subseq from] Beta-lactamase n=1 Tax=Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_35_23 TaxID=1798274 RepID=A0A1G0G0W3_9GAMM +----QTQLDQLEKSFGGKIGVYAIDTNTNQII-MHHADERFPVQSTMKLIAVAALLKQSD +KDANLLQEKIHYSEKDLTYWHPVTGQNVTAGMTLEALSEAAISYSDNVAANIIIKKLGGP +QAVTAFAHSIGNPSFNVEHYEGNLNSN-PQNTEDTSTPKDMAISLQKLTLGDVLTSAQRT +QLVTWMRNNTTSYKRMRAGVSVGWTVADKTGSGDYGIANDIGILWSPSCKPIVLAVYTVR +NKQDAKSQDDIVAATTSTVLETf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella sp. 362-Apple TaxID=678977 RepID=D7PIJ9_9GAMM +-----------------------------SQI-AYRADERFAMCSTSKFMAASAILKQSE +TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP +QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVSLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PEKDAK----------------- +>[subseq from] Beta-lactamase n=1 Tax=Amnibacterium setariae TaxID=2306585 RepID=A0A3A1U386_9MICO +-qALQRELDDLEARYGARLGVTAIDTGTGRRL-THRADERFAFASTNKAFIAAATLRSAS +--AADLDAVVRYARSDLLASAPITSRHVDTGMTVRALLDAAVRYSDNTAANLLVRRLGGT +AAVERFLRSIGDRTTSVDRLEPDLNTATPGDERDTTTPAASARDVEAVLLGSALPRERRA +VLDDLMTRSSTGGLYIRAGVPAGWAIADKTGSGAHGTRNDIAVLRPPGRAPIVLVLLSRR +VAEDAASDDALLADATAAVVR-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. ISID311 TaxID=2601673 RepID=A0A5C6WDY5_9ACTN +-dELSRRLTDLEQQHSARLGVFAHNPATGRSV-VHRADERFPMCSLFKTLAAAAVLRDLD +HHGEFLAKRIRYTTKDVRKYAPVTGTNLARGMTVADLCAAAISYSDNAAGNLLLRELGGP +TAITRFCRSTGDRITRLDRCEPELNSAEPSRITDTTSPRAIGQTYARLTLGTALTPKDRK +RLTDWLRATTTSGEKFRAGLPSDWAVADKTAGGKYGTNHDVGLTWPPGRSPIVMAVLTTK +REPDATADNPLVAKTAALLAK-- +>[subseq from] Beta-lactamase n=1 Tax=Acrocarpospora macrocephala TaxID=150177 RepID=A0A5M3WV95_9ACTN +--------------------MYALATGTGATV-TYRADERFAFCSTFKALAAAAVLHQNP +--LSHLNKRVTYTSAEVNSISPITENHIGTGMTIRQLCDAAVRYSDGTASNLLVRDIGGP +AQLTAYLRGLGDTVSRMDNYEPELNSNPPRNPRDTTTPRAIAADYHKLVLDDALTTGKRA +LLKDWLERNTTGDKRIRAGVPQGWTVADKTGTGNYGRANDIAIVWPPDTAPLVMAIMSDR +SGYSTPHKESLIAEAAARIV--- +>[subseq from] Beta-lactamase n=1 Tax=Desulfovibrio sp. MES5 TaxID=1899016 RepID=A0A231P3B1_9DELT +--ELIEKISQIERLSGGRLGAARLDCATGSLF-TYRGDEAFPMCSTFKVLAAAAVLKLHP +---QKLNNLVHIRPDEIVAWSPVTEKFVNRGIRVNQLCAAALQYSDNTAANLLLGMIGGP +SGLTAFARSLGDSRFRLDRMEPALNSAEPGDMRDTTSPAAMAATLNTLLMGEALPLQHRE +LLRQWLTECATGASRIPAGTPAGWKVGHKTGSGPNGTSNDVGILLPPAGTPVILALYLTQ +CAAAANDRDATLAATTSL----- +>[subseq from] class A beta-lactamase n=1 Tax=Frondihabitans sp. Leaf304 TaxID=1736329 RepID=UPI000A079FD8 +-qSTRAEFSALENKYGARLGVFAVDTSSEKTI-AYRPGERFAFASTYKALAAGILFKQST +--EDELDHTIHFTESDLVDYSPVTEKHVASGMTVREIIAAALQYSDNTAANLMLDQLGGP +AGLTESLRSLGDTTTSVDRPEPGVNEAIPKDPRDTTTPAAIAGDLRSFLLGGALAAPRRA +EMTTLMLGNTTGAPWIRAGVPSTWKIADKTGNASYGTRNDIAVAYPPGRAPIVIALLSDR +GTVDATSDDGLLADATRIVV--- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase FRI-7 n=1 Tax=Enterobacter asburiae TaxID=61645 RepID=A0A455W340_ENTAS +-----EQMRELETSFGGRIGVYILNTKNGKEF-SYRQDERFPLCSSFKAFLAASVLKRTQ +DKSVSLDDMMEYSGRVMEKHSPVSEKYRETGASVQTLAKAAIQYSDNGASNLLMERIGGP +EGLTAFMRSTGDTDFRLDRWELELNSAIPGDERDTSTPKAVAMSLNNIAFGSVLDAKNKS +LLQDWLKGNTTGNARIRAAVPDKWVVGDKTGTCGYGTANDIAILWPDANSPAVMAVYTTR +PNQNDKHDETVIKNAAKIAIN-- +>[subseq from] Beta-lactamase n=1 Tax=Marinobacter sp. R17 TaxID=2484250 RepID=A0A3N2QZS9_9ALTE +-eDLSDTVEQVEDQLDARVGLAMTDTGSDFSW-SHRADERFLMNSTMKVPLCGAVLAQVD +AGKMSLSDELPVHQDDILSYAPVTKERVGQSMTLDELCYAALDMSDNTATNLLIRHLGGP +EAVTQFLRRIGDSVTRSDRYESALNTWEPGDPRDTTKPVVMIDTLQKLLLGDALTTSSRD +QLVAWMSHGGVTQALLRDDAPSSWKIADKSGSGDH-NRNIVALITPDDGDPRIVTIYISD +TDADFKARNAALKELGAAVIR-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00066A1968 +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDGTRNDIAVLWPHGGTAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Pasteurella multocida TaxID=747 RepID=Q83ZX4_PASMD +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGRSIFDVy +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium parafortuitum TaxID=39692 RepID=A0A375YJZ1_MYCPF +---AQDRIAALGQRHNAQIGLYAANLDTGDSL-AFGDTERFAMCSTFKAYAAGAVLQRVQ +QGALRLGDTVPIRAEDIRPHSPVTEPWVGTEMTLAELCQAALQQSDNAAANALLGVLGGP +PAITEFARGIGDDQTRLDRWEVELNSAVPGDPRDTSTPRALGTGYRALLTGDVLEPAGRQ +QLTDWMLANQT--SSMRAGLPQGFTSADKTGSGDYGTTNDVGVVFGPDGQRLVVAVMTRS +ITPDAPSLRPLIGELATLVL--- +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=A0A2S1LUM6_CITKO +--------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD +RKAQALSASTQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP +QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE +QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ +TPATMAQRDAAIVRIGESLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium parafortuitum TaxID=39692 RepID=UPI00138D9582 +----QDRIAALGQRHNAQIGLYAANLDTGESL-AFGDTERFAMCSTFKAYAAGAVLQRVQ +QGALHLRDTVPIRAEDIRPHSPVTEPRVGTAMTLAELCQAALQQSDNAAANALLGVLGGP +PAITEFARGIGDDQTRLDRWEVELNSAVPGDPRDTSTPRALGTGFQALLTGDVLEPAGRQ +QLTDWMLANQT--SSMRAGLPQGFTSADKTGSGDYGTTNDVGVVFGPDGQRLVVAVMTRS +ITPDAPSLRPLIGELAALVLA-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000752FC89 +--AAQAQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLIGTANSVAGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. AU18528 TaxID=2015350 RepID=A0A2G1SBE3_9BURK +----QAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGA +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PEATAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces malaysiense TaxID=1428626 RepID=A0A1J4Q7K2_9ACTN +------ELADLERRYGARLGVHARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA +-RCAPMDKVIHYPPHDLLPNSPRTEENQPTGMAMAEVCAAAIQYSDNAAGNLLLRQLDGP +AGLTRFFRSLGDGVSRLDRWEPELNTAVPGDPRDTTTPGAVAASIERLALGRALAAPDRE +RFVAWLKGNTTSGTRFRAGLPVGWTVADKTGTGDYASANDVGVAWTTRRTPVVLAVLSTK +EDKDAPVDEALIAEAARIAAR-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 130 TaxID=2591006 RepID=A0A552RKB0_9ACTN +---TTARLRELERTHGARVGAFAYNVATGVSV-RHRADERFPMLSTFKTLAAAAVLRDLD +RDGEVLEKVVHYTKADCVSDSPVTDTSIASGLSIARLCDAAIGDSDNTAGNLLLRELGGP +QAVTRFARSLGDRETRLDRWEPDLNSAEPGRVTDTTTPAAIARDYARLVLGNALEPRDRA +LLTHWLLNCRTSGTRFRAGLPPEWTVADKTGGGFYGSCNDVGVAWTEEGAPVVLAVLTTK +PASGAAGDHPLVRDVAKALA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI0011A1379D +----DSEFAALEEQFDARLGVYAVDTGTGREI-EWRGDERFAYASTIKALAAAALLDDVG +--TAGLAKTVEIGASDIIKHSPVTETRVGQSMTLDEICEAALTQSDNAAANFIFAELGGP +QAFDAQLDELGDAGTTVSRIEPDLNEALPGDFRDTTTPRASANNLREYVFGDALDDEEKT +ALTDWMKASQTGDTLVRAQLPEDWTVGDKSGGGMYGSRGDLAVVWPTDGRPIVISVLSSR +DEREADYDDRLIAGAAAAAVDQ- +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis methanolica 239 TaxID=1068978 RepID=A0A076MNC8_AMYME +------DFADLEARFDARLGVYAIDTGTGREI-AHRADERFNYASAIKSLLAGAVLRRNV +----DLDKVVAYTDADVQPNSPVTKDR--RSVTVREAAEAALLQSDNTAANLLFAEVGGP +AGLAAVLRDIGDTTTHPDRLEVELNSAIPGDVRDTSTPRAMAGSLRAFLLGEALPADKRD +LLVGIMRRNKTGTELIRAGVPSEWPVADKTGTGDYGTRNDIGVIWPPGHAPIVLALMSSR +ATADASYDNKLLAEATSRVMD-- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=UPI00068196A7 +--KINEDLAAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLNDMD +NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSVGGP +RGVTMFLRTIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITS +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A1B4PZY5_BURCE +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGS +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIAQLCVAMLQSGDKSAANLLMGVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPPGWRIADKAGTGGYGTTTDVAMLWPPSRAPIVMAVSFTQ +PGADAAPRADVVASAARIVA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI000CC8ED02 +--QLSEDISLIEQQTSSRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLIAQISQLILQKy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2S1Q3L7_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTN--------------------- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Leifsonia sp. 71-9 TaxID=1895934 RepID=A0A1M3LRJ3_9MICO +---TQRAFAELERTHGATLGVTAIDTGSGRTV-AYRGGERFPFASSNKTFIAAALLQRSS +--DADLDQVVHYTSADLLSYAPITSRFVDTGMTVRELIDAMLRFSDNTAANLLVARVGGP +DAVEQWLRGIGDRTTNVDRIEPDLNEALPGDARDTTTPAQFASDLRSVVLGSALETTDRT +LLRNTMLDNTTGDDTIRAGVDPAWPVADKTGTGEYGVRDDIAVVYPAGRAPIVVVTLSRK +AAPDATPDNALLAAATKTAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Embleya scabrispora TaxID=159449 RepID=UPI000C7BFF2F +------RLRALERAHSARLGVFACDAVSGRAV-VHRADELFPMCSSFKTIAVAAVLRDLD +RDGQFLGSRIRYTEKDVTEYAPITGRNLADGMIVADLCAAAIAYSDNGAANLLLRRLGGP +GAVTGFCRSVGDEVTRLDRWEPALNSAEPGRVTDTSSPRALGRTYARLALGGALDARDRE +RLTGWLLANTTGGKRLRAGLPAGWVVADKTGTGSCGTTNDVAIVRPPDRGPIVMAVLSTK +DDAAAPADEALLAETATVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Jiangella aurantiaca TaxID=2530373 RepID=A0A4R5AD73_9ACTN +----AAALAALETDYAARLGVYAVDTGTGETV-EHRADERFAFASTHKMLSAAAVLQATE +--PAELAQVIPFDAADVVGFSPVTEPAVGTGLTLLEVIQAAITVSDNTAANLLFEQVGGP +DGLEAVVRGFSDETTSFDRIEPDLSEWAPGETRDTTTPRAMAANLRGLLLGDLLAEEDRT +LLHDTMRANTTGDELIRAGVPEGWVVADKTGSATHGGRNDIAVIEPPGAAPIVLAVYSNR +LDPEAESDPALIAAATAIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Leifsonia sp. NCR5 TaxID=1978342 RepID=UPI0011799599 +--ATSRAFAALERTHGATLGVTAVDTGNGRAV-GYRSGERFPFASSNKTFIAAATLQRTT +--TADLGTVIHYTRADLLDYAPITSRFVDTGMTVRELLDAMLRFSDNTAANLLVARLGGP +DAVEQWMRGIGDRVTNVDRVEPDLNEALPGDPRDTTTPAQFAADLRTVVLGKTLETADRT +LLRNTMLDNTTGDETIRAGVDPAWPVADKTGTGEYGVRDDIAVVYPAGRAPVIVVVLTRK +DTPDATPDNALVAEAAKVAVR-- +>[subseq from] Uncharacterized protein n=1 Tax=Frondihabitans sp. Leaf304 TaxID=1736329 RepID=A0A0Q5CHS1_9MICO +-qSTRAEFSALENKYGARLGVFAVDTSSEKTI-AYRPGERFAFASTYKALAAGILFKQST +--EDELDHTIHFTESDLVDYSPVTEKHVASGMTVREIIAAALQYSDNTAANLMLDQLGGP +AGLTESLRSLGDTTTSVDRPEPGVNEAIPKDPRDTTTPAAIAGDLRSFLLGGALAAPRRA +EMTTLMLGNTTGAPWIRAGVPSTWKIADKTGNASYGTRNDIAVAYPPGRAPIVIALLSDR +GTVDATSDDGLLADATRIVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces varsoviensis TaxID=67373 RepID=UPI000998C1E1 +--DLSRQLRALETEYKARLGVYALDTATGATV-SYRAAERFPMCSVFKVLTAAAVLRDLD +RDGEFLAKRIRYTEKIVKKYTPVTGKNIANGLTVEQLCAAAVSESDNGAANLLLRELGGP +TAITRFCRSIGDKTTRLDRWEPELNSAEPWRETDITTPGDIGKTFARLIVGRALPSEDRK +RLTGWLVANTTDGERFRAGLPADWILADKTGGGQYGVANDVGVVWPPKRSPLVLSVLSTK +YDPKGPTDNPLVARTAALVADH- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075DEFD2 +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRACVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +AGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1U9YFZ2_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTN--------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium syngnathidarum TaxID=1908205 RepID=A0A1S1KJ70_9MYCO +----DDGIAELERRNNAFIGLYASNLDSGRTL-THRADEMFAMCSTFKAYAAARVLQMAE +HGEVSLDNRVFVDREAIVPNSPVTETRAGGEMTLAQLCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPSALAVGYRAVLAGDALSPPQRR +LLEDWMRANQT--SSMRSGLPEGWTTADKTGSGDYGSTNDAGIAFGPEGQRLLLVMMTRS +QA-DDPKAEPLIGELTA------ +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9142 TaxID=2184573 RepID=A0A3N8AL89_9BURK +--AAQAELAALETASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVAAAAAILARGS +LDASLLPRRILYRRYDVVAGSPVTESHVDTGMTIAQLCAAMLQAGDKGAGNLVMGVLGGP +QAVTSFAHESGDSAFRLDRWEPELNQVAPGDVRDTSTPVAMVDLLQRLLLGDTLREPQRA +QLTEWMTGGARGAAGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces lincolnensis TaxID=1915 RepID=A0A1B1M176_STRLN +----APKFRALEREFDARLGVYALDTGTGRSV-GYQPDDRFAYASTFKALAAGAILRKYG +--TDGIDKVVTYSRDDVVADSPVSENFVETGMSLRGLCAATLWYSDNTAVNLLLDELGGP +DGLEKVLEEFGDDVTEMDRYEPEMSDGTPGDIRDTSTPRAMAESLRAFLLGDALKRDERE +LLRQWMTTNMTGRTLIRAGVPDGWDVADKSGSAGYGGRNNIAVVWPEDGNPIVMAVMSTR +GKQGADRRDALIAKAATVAAD-- +>[subseq from] Beta-lactamase n=1 Tax=Georhizobium profundi TaxID=2341112 RepID=A0A3Q8XLC1_9RHIZ +--RLQEVVSTIEENLDARVGIVVRDSGSDWQW-AHREDERFLMNSTFKSVLCGAVLQRAE +MGELALTETLEIEASDILDYAPVAETRVGESMTIGELCLATLDMSDNTAANLLISRLGGP +QEVTAFMRSLGDSVTRLDRLEPEMNSFAEGDPRDTTTPAAMAASWETMLLGDGLSPASQA +QLIEWMSIGGVTGALLRASTPEDWLVADKSGSGNR-TRNLVAMVTPPDETPYVVSIYLSG +TTADFQARNAAVTEIGAAIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A2I5JVQ1_ENTCL +-----AQIKELETVFGGRIGVYLLNTENGKEF-SYRQNERFPLCSSFKVFLAASVLKKTQ +DKSFSLNDTVEYSDRVMEKHSPVSEKYLETGASVQTLAMAAIQYSDNGASNLLMERVGGP +EGLTAFMRSTGDTEFRLDRWELELNSAIPGDKRDTSTPKAVAMSLKNIAFGSVLDAKNKA +LLQDWLQGNTTGNARVRAAVPDKWVVGDKTGTCGYGTANDVAILWPDSNSPAVIAVYTTR +TNQNDKHDETIIKNAAKIAIN-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. NAS80.1 TaxID=1680159 RepID=A0A1Q5RIB6_9BRAD +---IEPRLKELEARSGGRLGVAVLNVATGQVI-GNRVDERFAMCSTFKALAVAFVLARVD +RGEERLDRRVVFTERDLVPPFNATKPHVGPEMTIAELCEAAVTVSDSTAANLLLASFGGP +AALTAYLRSLGDPVTRLDRIELDLNIVKPGDIRDTTTPGAMVETLHRLLLGDVLSKSSRA +RLTTWMVEARDATRRLRVGLPAGWRIANKPGTWEKISTNDIGVIWPPDRDPIVLAAYLGE +APGSVKVQEGILADVARIVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Phytoactinopolyspora sp. XMNu-373 TaxID=2650750 RepID=UPI0013917B1C +--RLDERFEDLESAYDARLGVYVLDTGSGQDI-TYRADERFAYASTFKILLCAVVLDQHS +--FDDLEELITFSADDLQAHSPITSERVETGMTIRELCDAATRYGDNTAVNLLLDVLGGP +SGLGEALKAAGDDVISVDRYAPELSEATPGDTRDTSTPRALATTLRLFALEDALPEDKRE +LLTEWMVGNLTGEDLIRAGIPDDWTVGDRTGAAHYGTRNCIAIVWPPDRDPILIALLTSR +DTEDAERQDELIVEATEAIVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI00075E622C +----QAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGA +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAVPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTSDIAVLWPPSRAPIVMAVSFTQ +QEATAAARADVVASAARIAA--- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=UPI0009386A23 +--KINEDLAAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLNDMD +NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSVGGP +RGVTMFLRTIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRAITAMIWKENHKPVYISIYITG +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] Beta-lactamase n=1 Tax=Trueperella pyogenes TaxID=1661 RepID=G3K0V2_9ACTO +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGNGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGHSIFDVy +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. NEAU-CX67 TaxID=2571143 RepID=A0A4U0Q9W4_9NOCA +-qSLDTKLDALEARYATRIGVTVINPATGQIY-QHRGDERFALCSTFKTYAAAEVLRRTR +AGTSSLDKPVLVEPGDLVENSPVTAAAVGTPMTLRQIAEAALTRSDNTAGNYLLEEIGGP +PAITSLAREIGDDSTRLDRWETELNSALRGDPRDTSTPNELADGYRALLLGDALGSPERA +QLVDWMRASKTSDKRIRAGLPDGWTAAAKSGAGRFGTVNDAGVAWDQDGNPLVLAILTDS +LTEDAPGNNQVVADTTAAVVE-- +>[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces sp. 136MFCol5.1 TaxID=1172182 RepID=A0A1G5GUM1_9ACTN +--RTARELRALEREHSARLGAYAHDTATGRTV-VYRPDERFPMCSLFKTIGVAAVLRDLD +RRGEFLARRIRYTAQYVEANSPITGRNLSGGMTVAELCAYSITHSDNTAANLLLRELGGP +GAVTRFCRSIGDPVTRLDRWEPELNSAEPWRGTDTTTPRAVGRTYARLVLGDALVPCDRR +LLTGWLLANTTSGERFRAGLPADWTVADKTAGGSYGGNNNAGIAWPPGRPPVVLAVMTTK +PDRDAPADNPLVARTAGVLA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111DBF05 +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLGPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCBA15_012 TaxID=1898738 RepID=A0A1S2I0E8_9MICO +--ATRQAFAALEARSGARVGVVALDTGDGHAI-GYHADERFAFASTNKVFIAAAVLDAAT +--GSDLDEVVHYDRGDLLSYAPVTRPAVDTGLTVRQLVDAAVRSSDNTAANLLVERLGGV +EAVSRWLRSTGDDVTDVSRTEPDLNTAVPGDRRDTTTPAQSATDLRAVLLGDVLDADDRA +LLLGSMRGTTTGDGTIRAGVDPAWTVADKTGTASYGVRNDVAVVTPPGRDPIVLVVMTSH +PAPDAEPSDALVAEATRTAVE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A119UUU8_9BURK +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAIAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F58F9E1 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMTGGTRAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PDAAAAARADVVASAARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A4Q6FN72_9PROT +---LSNDFEKLEHETGGRVGVSAWDVTSGERI-GYRAGERFPFCSTFKTLAVAAALKQGG +-----LAKRLHFTADDVKKYAPITTKFVDQGMTVSELSAAAIQYSDNAAVNSLMTHLGGL +QTVNAFARTLGDEVFRLDRWEPELNSAEPSDTRDTTTPDAMTGSVHKILLGDALPPAARA +LILAWHKTNTTGDKRIRAGIPKDWTAAEKTGTCSYGTTNDAGVIWRADGSPIVLTIYFTG +RDKDAKPNDAAVAYVAKIISE-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium setense TaxID=431269 RepID=A0A0B2Y181_9MYCO +---IDDQIAELERRDNALIGLYATNLDSGRTI-THRPDEMFAMCSTFKGYAAARVLQMVG +RRQISLDNRVFVDPDAIVEYSPVTEPRAGGEMTLGELCRAALQQSDNTAGNLLLKTIDGP +PGITAFARSIGDQRTRLDRWETELNSAIPGDPRDTSTPAALAGGYREILAGDALSPPQRR +QLQDWMRANET--SSVRAGLPEGWTTADKTGSGDFGSTNDVGIAYGPDGQQLLLAVMTRS +QADDPKADNPLIGELA------- +>[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas sp. NML171200 TaxID=2480816 RepID=A0A4V2HDE8_9GAMM +-----KDFAALEQVSGGRLGVTLLEVAAGRRL-GRRQDERFPMCSTFKALLAAHVLSLAD +AGTLSLDERLPIRQAQLLSWAPESERHVGKDLTVRDLCRAAVTNSDNTAANLLLARAGGP +PALTAFLRRQGDAVTRSDRYEPEMNNFAPGDPRDTTSPAAVAASLARFAVGDGLSKASRA +QYADWLIDNQTGDDCLRAGLGKRWRVGDKTGNNGRDTRNDLAVLWPLGGTPWVLVALLQG +ARVDADQRDAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Phaeobacter inhibens (strain ATCC 700781 / DSM 17395 / CIP 105210 / JCM 21319 / NBRC 16654 / NCIMB 13546 / BS107) TaxID=391619 RepID=I7DZ10_PHAIB +--DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD +RSTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP +EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTATPRSVLSTLHAALSGTMLSGSSSA +QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE +TDADFAQRNQAISDIGRAMI--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria MEX-5 TaxID=396597 RepID=B1SXG5_9BURK +--AAQAELAALEKASNGRLGVAVLDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTVFRLDRWEPELNQAAPGDERDTSTPVAMVDMLQLLLLGDTLREPQRA +QLTEWMTGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDIAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIAT--- +>[subseq from] Class A beta-lactamase n=1 Tax=Mycobacterium persicum TaxID=1487726 RepID=A0A657QEK6_9MYCO +--DVQSRFAELEHTYAARLGVYVPASGTTAAI-AYRADERFAFCSTFKGLLVAAVLHQYP +--LSHLDKVVTYTSADIRSTSPITQQHIATGMSIGQLCDAAIRYSDGTAANLLLAEIGGT +TAFTGYLRSLGDSVSRLDQEEPELNRDPPGDERDTTTPHAIALDYQQLVLGDALPADKRA +MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPTGVPHVVAILSDR +AGYDAEPSEALVADAARCVAQ-- +>[subseq from] Beta-lactamase class A n=2 Tax=Solirubrobacter pauli TaxID=166793 RepID=A0A660L350_9ACTN +-----AALRRLERRHDARLGVYALDTGTGREL-AYRADDRFPFASTFKALAAAALLREVG +--VDGLRKTVPVE--QLVNYSPVTEQRLGTRMSLNALASAAVRYSDNTAANLLLDELGGP +KGLDAILAEEGDDVTRMDRPEPDLNVWEPGQVKDTSTPRALAGSLRTFVLGDALDAPERA +QLTRWLRTNTTGGALIRAGVPDDWTVGDKTGTGAYGARNDIAVLWPPERDPIVLAIMTRG +RAADAEPDDALVAAAAKATI--- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium citreum TaxID=2036 RepID=A0A1C7CEA7_9MICO +---TRQAFADLERRDGARVGVVAVDTGTGRSL-GYRADERFAFASTNKVQIAAAALAASS +--PADLDEVVHYDRGDLLSYAPVTTPAVDTGLTVRQLVDAAIRQSDNTAANLLVERVGGV +AGVTRWLRGLGDTTTDVSRTEPDLNTALPGDRRDTTTPAQSAADLRAVLLGDALDADDRS +LLRDAMLGTTTGATTIRAGVDPSWTVADKTGTASYGVRNDVAVVTPPGRDPIVLVVMTAH +GTADAEPSDALVAEATRIAIAH- +>[subseq from] Class A beta-lactamase n=1 Tax=Embleya scabrispora TaxID=159449 RepID=A0A1T3NNX6_9ACTN +------RLRALERAHSARLGVFACDAVSGRAV-VHRADELFPMCSSFKTIAVAAVLRDLD +RDGQFLGSRIRYTEKDVTEYAPITGRNLADGMIVADLCAAAIAYSDNGAANLLLRRLGGP +GAVTGFCRSVGDEVTRLDRWEPALNSAEPGRVTDTSSPRALGRTYARLALGGALDARDRE +RLTGWLLANTTGGKRLRAGLPAGWVVADKTGTGSCGTTNDVAIVRPPDRGPIVMAVLSTK +DDAAAPADEALLAETATVLAE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=G3JVG9_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGE-------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Kitasatospora sp. SolWspMP-SS2h TaxID=1305729 RepID=A0A327ST05_9ACTN +--DLRDALAALEREHGARLGVFAHDTGSGATV-RHRADEPFPLCSTFKPLAVAALLHAGD +----DLSARVHYTDQDVADYAPVTGR--TRVLTVAELCAAAIEFSDNTAANLLLRRLGGP +TAVTRFCRSIGDRVTRLDRWEPALNSAEPGRVTDTTSPRALARSYARLTLGDTLAPAHRA +RLTAWLLANTTGANRLRAGLPASWTLADKTGTGSYGTANDAGLARPPHRAPIVLTVLTTK +PTPDAAPDEPLIARTAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759EE59 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGDYGTTTDVAVLWQPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=A0A2S9KPT7_9BURK +--AAQAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPVCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP +QAVTSFAHESGDTVFRLDRWEPALNLAAPGDERDTSTPVAMVDLLQQLLLGDTLREPQRA +QLTEWMNGGTRGATGIAAGMPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIAT--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Curtobacterium TaxID=257496 RepID=UPI0009F3EA21 +--ATRQAFAALEARSGARVGVVALDTGDGHAI-GYHADERFAFASTNKVFIAAAVLDAAT +--GSDLDEVVHYDRGDLLSYAPVTRPAVDTGLTVRQLVDAAVRSSDNTAANLLVERLGGV +EAVSRWLRSTGDDVTDVSRTEPDLNTAVPGDRRDTTTPAQSATDLRAVLLGDVLDADDRA +LLLGSMRGTTTGDGTIRAGVDPAWTVADKTGTASYGVRNDVAVVTPPGRDPIVLVVMTSH +PAPDAEPSDALVAEATRTAVE-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00084AF2C1 +--KLNEDISLIEKQTSGRIGVSVWDTQMDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSVGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6D1LSF7_ECOLX +--------------------------ADNAQT-LYRADERFAMCSTSKVKAAAAVLKQSE +TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA +QLVTWLKGNTTGAASIQAGLPTSCVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ +PEQKAESRRDVLAA--------- +>[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. LHW52907 TaxID=2303421 RepID=A0A372GGY9_9ACTN +--DVTRRLLRLEKARDARVGAYAIDTGTGQVL-AHRADERFPFASSFKVMACAAVLQKAR +RDPGLMDRVIRYDRRDLAAFSPETEKHVGTGMTVAELCGATITKSDNTAGNLLLKEIGGP +RGLTAFFRSLGDTVSRSDRVEPGLNRWRPGELRDTTAPGPWARDLRALTVGDALVPADRE +RLVAWLKASVTGGERIRAGLPGGWTVGDKTGTAGHGNANDIAVVWPPSGAPLIFAILVTR +PDADAEPDDETVAAAARILA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces agglomeratus TaxID=285458 RepID=A0A1E5P1S6_9ACTN +--RISRRLRDLEREHSARLGVYARNMVTGKTV-AHGAHERFPMCSTFKTIAVAAVLRDLD +HDGTFLAKRIHYTAEYAKAYDKITGQNVTNGMTVEELCGAAISYSDNAAANLLLNELRGP +TAVTRFCRSIGDGTTRLDRWEPELNSAEPGRITDTTTPRAIGRTYARLVLGNALAPADRK +RLTGWLLANTTSDEKFRAGFK-GWTVADKTGSGSYGTTNDVGVVWTPKGSPIIVSVLTTK +HEADAAADGALVRRAAELL---- +>[subseq from] Beta-lactamase n=1 Tax=Saccharothrix sp. NRRL B-16348 TaxID=1415542 RepID=A0A0M8YFP6_9PSEU +------HLIELERKFDARLGVYAVATGTGTTL-AYRADERFAFCSTFKGLAAAAVLHRHP +--LSHLDTVVTYTERDLMASSAITRQHVATGMTVRQVCDAAVRHSDGTAGNLLLRDLGGP +AGLTAYVRGLGDTVTRSDRVEPDLTTAVPGDPRDTTSPRAIGVDYREIVLGDALEPDKRA +FLRDLLERNATGTQRVRAGVPQGWTVADKTGTGDYGTVNDIAVVWPPNAAPLLISIMSSK +AAADDGYDQALLAEAAAYAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium aphoticum TaxID=754436 RepID=A0A090QGA8_9GAMM +---VQTQIQAIEQTLSAHIGVAVLDTQNNTRW-SYKGDERTPLTSTFKTLACAKLLHDAE +NNTLALIDTVTIKASELVTYSPVTEKWVGKAIPVVQACEATMFTSDNTAANIVIHAVGGP +DKITAFLRQSGDAVTQLDRLEPALNEATPGDVRDTTTPNAMTQTLNTLLFKEGLSKENQQ +QLIDWMMGNQVTGNLLRSVLPKSWTIADRSGAGGHGARSITAVVWPEDRAPVIIAIYVMQ +TEASFDARNQAIVTIGQAIFNLy +>[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium kunshanense TaxID=1445034 RepID=A0A328BFB1_9CAUL +-------WSALESRVGGRLGVFAINAGTGRSL-GWRASERFPMCSTFKGLLAGAVLARVD +AGREQLDREIPLSEADLVAHAPVTSLYVRAGIRVDTLCKAIVEVSDNPGANLLLKTLGGP +AGFTAWLRTTGDNITRLDRYETELNSAIPDDPRDSTSPMAMVGSYRRLLLGPSLESASRQ +RLAGWMEGASTGLKRLRADLPAGWRAGDKTGSGANNTANDVAILWPPRGAPILVGCFSTQ +ATAP-EARDAVMAHIGRLAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TAA040 TaxID=1288083 RepID=UPI0004013536 +-kRAEQALAQLEERFDARLGFYLLDTGTGREI-THRADERFSYASTFKALAAGVLLGTST +--DEELDRVVRYDESDLLEYAPVTSEHVDTGMTLDALIAAAVQYSDNTAANLMLEELDGP +EGLQKALRDLGDTTTSVDRIEPDLNGFAPGDDRDTSSPRALGTDLRRFVLGDALPEDRRE +RLTDLLLGNTTGDDYIRAGVPDGWRVGDKTGGGGHGTRNDIAVVWPDSGAPLVLAIVSDR +GEEGAASDDALLAEATEA----- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium persicum TaxID=1487726 RepID=A0A498PEK6_9MYCO +--DVQSRFAELEHTYAARLGVYVPASGTTAAI-AYRADERFAFCSTFKGLLVAAVLHQYP +--LSHLDKVVTYTSADIRATSPITQQHIATGMSIGQLCDAAIRYSDGTAANLLLAEIGGT +TAFTGYLRSLGDSVSRLDQEEPELNRDPPGDERDTTTPHAIALDYQQLVLGDALPADKRA +MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPTGVPHVVAILSDR +AGYDAEPSEALVADAARCVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F593053 +--TAHAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAVLWPPSRAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Lechevalieria xinjiangensis TaxID=402600 RepID=A0A1H9IWT4_9PSEU +----TGRLRELERQHNARLGVFAAETATGRTV-LHRADELFPMCSTFKTIAAAAVLRRDH +-DGTLLGKVITYTQADVDKYGPITGRNLAAGMTISALCEATITYSDNCAANLLLRELGGP +TAISRFSRSIGDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGQSYARLTLGHALDRADAD +QLTKWLLANTTGGNRIRAGLPAAWRWGDKTGTGKHGTTNDAGVAFPPGRSPIVIAVLSTK +ATPDAPADEPLLAKAAELVAGMf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2U9GMV8_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTCMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDI------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 2131.1 TaxID=1855346 RepID=A0A1H5CZZ3_9ACTN +---TTARLRELERAHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD +RDGEVLEKVVRYTKADCVSDSPVTDTHLASGLSVARLCDAAIGDSDNTAANLLLRELGGP +AAVTRFARSLGDRVTRLDRWEPLLNSAEPGRVTDTTTPSALARDYARLVLGNVLERRDRG +RLTHWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYGSCNDVGVAWTPEGVPVVLAVLTTK +PASDAAGDHPLVRDAAEALA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI0007686F0F +----QAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGA +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAVPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +QEATAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodovulum visakhapatnamense TaxID=364297 RepID=A0A4R8G8Y2_9RHOB +-qALADTISRLESALPARIGVAIRDSGSDWGW-GHRDSERFLMASTFKSVLCAAVLDRAD +RGLLSLGDAVAIPPEAILDYAPVAETHVGGTMTLGDLCLATLDMSDNTAANLLIARLGGP +QEVTAFLRRIGDPVTRLDRTEPDLNLLDPADPRDTTSPAAMAATWQRLLLGDVLSPASRA +RLADWMSHGSVTASLIRASAPPGWTVSDKSGGGREYTRNLVAMIRAPGRAPVVVAIYLSD +CPADWATRNAAVAEIGAAVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000841975D +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMAGGTRAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PDAAAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium peregrinum TaxID=43304 RepID=A0A1A0QSD2_MYCPR +---VDDQIAELERRDNALIGLSATNLDSGRIL-THRPDEMFAMCSTFKGYAAARVLQMVG +RRQISLDNRVFVDPEALVPNSPITEAHAGSDMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALALGYREILAGDALSPPQRR +QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPNGQRLLLAVMTRS +QADDPKADNPLIGELT------- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3N9G5Z9_9BURK +--TAHAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPSRAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Lentzea waywayandensis TaxID=84724 RepID=UPI000B87F0A4 +------ALFELEKKFDARLGVYAMS-DNGSTI-EHRADERFAFCSTFKGLAAAAVLHRNP +--MSHLDTVVTYTEADLMKSSTITRQHVRTGMKLRDLCDAAVRYSDGTAGNLLLRDAGGP +AELTKYLRGLDDTETRMDRIEPGLTSAVPGDPRDTATPRSLGTDYQRIVLGDALEPEKRD +FLRDLLERSTTGAKRVRAGVPQGCRVANKTGTGEYGTVNDIAVVWPPNREPVLIAIMSSK +SAADAKYDEALVAEAAAYVLK-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium neoaurum TaxID=1795 RepID=UPI000B06E39A +--ALPERIRDLEARHNAFIGVFGMNLDSGMSV-RHRAEEPFAMCSTFKTYAAAAVLRRVA +EGELSLDKPVFVDPAGILPNSPVTEERAGGQMTLAELCQAALQRSDNLAANLLLATLGGP +RAITDFARSIGDDKTRLDRWETDLNSAIPGDPRDTSTPEALGTGYRNLLAGDALPPAQRD +LLDGWMRANQT--SSMRAGLPPDWTTADKTGSGDYATTNDVGIAYGPGGSRVLLSIMTRT +QSPDAEGLRPVIGEIAALVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces iakyrus TaxID=68219 RepID=UPI0005251D7F +------RLTDLEREYGARVGVYALATGTGATV-VHRAGERFAFCSTFKALAAAAVLHHRT +--VSGLDRRVTYTEADLRSTSPVTGRHVATGMTLRELCDAAVRFSDGTAGNLLMRDIGGP +PKLTAYVRSLGDEISRMDHYEPELHDVPPGDPADTTTPQAIAADFRRLLLGTALPARERR +LLMDWLSRNATGARRIRAGLPGDWKVADKTGTGDYGRANDIAVVHPPRTEPLVLAVMTDR +PGRDAEPSDALIAEATRRT---- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium kubicae TaxID=120959 RepID=A0A1X1XIU2_9MYCO +----TDRIDELESQYHAFAGVYAQDLDSGHTV-THRADDPFAMCSTFKAYAAGRVLQKAQ +GGELDLDQATFIDPNELQPNSPVTAPHAGHSMPLAQLCAAALQRSDNTAANLLLQAIGGP +PAITEFARSIGDDRTRLDRWEVELNTAIPGDPRDTSTPRALGAGIQNLLAGTVLAPPQRR +QLETWMRGNVT--STMRAGLPPGWTTADKTGSGDYGSTNDVGIAYGPNGQRVLLAIMTRS +QAPDADALQPLIADVTRAVL--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. EPG1 TaxID=2064767 RepID=A0A2S7NKQ4_9MYCO +----QDRIAALGQRHNAQIGLYAANLDTGESL-AFGDTERFAMCSTFKAYAAGAVLQRVQ +QGALHLRDTVPIRAEDIRPHSPVTEPRVGTAMTLAELCQAALQQSDNAAANALLGVLGGP +PAITEFARGIGDDQTRLDRWEVELNSAVPGDPRDTSTPRALGTGFQALLTGDVLEPAGRQ +QLTDWMLANQT--SSMRAGLPQGFTSADKTGSGDYGTTNDVGVVFGPDGQRLVVAVMTRS +ITPDAPSLRPLIGELATLVL--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A5C0PCR9_PSEAI +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVNNQVTDNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGHSIFDVy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces chartreusis TaxID=1969 RepID=A0A5J6JV46_STRCX +---TTGRLRLLEQQHGARLGVFAYNVRTRRTV-THRADELFPMCSVFKTLASAAVLRDLD +RDGEFLGRRIHYTEADLPKGSDKTREHLAEGMTVAELCEVAITYSDNGAGNLLLRELGGP +TAITRFARSLGDPVTRLDRRETELNSAEPWRVTDTTSPRAIGRTYGRLVLDDALNRPDRR +LLTHWLLSNTTSGKRFRAGLPKTWTVADKTGSGSYGTTNNVGVAWTPDGTPVVLSVLSTK +PAQDAAWDDALVAETAALL---- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. ESTM1D_MKCIP4_1 TaxID=2072414 RepID=A0A3S7KUD4_9GAMM +------DFAALEKASGGRLGVTVLDTGSGRRLaGHRQDERFPMCSTFKSMLVAHILSLAD +AGRLSLDTRVPITERDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP +AALTAFLRAQGDTVTRNDRYEPDMNRFAKGDARDTTSPAAMAASLARFAVGDGLLQASRL +QFADWLVDNQTGDACLRAGLGPRWRVGDKTGSNGEDTRNDIAVLWPRAGTPWVITAYLQG +ASVDEEQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces harbinensis TaxID=1176198 RepID=UPI000B81CAF1 +-----GEFARLEDAYDARLGVYALDTGSGEEI-GYREDERFAYASTFKALLCGAVLEEYG +--LAGMDEVIPYGEEDLLPNSPITEERLAEGMSKSDLCDATVRYSDNAAANLLWDTIGGP +AGLQERLAGLGDDVTRMERWETELNEAVPGDERDTTTPEAFAGNLAGYVLGEVLPEPERA +QLTEWLVTNTTGDELIRVGVGEGWTVGDKTGGGGHGTRNDIAVLWPDSGPPLVLAVFSTR +EEPDADWDNALIAEAASVAV--- +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=unclassified Rahnella TaxID=2635087 RepID=D7PIJ0_9GAMM +-----------------------------SQI-AYRADERFAMCSTSKFMAASAILKHSE +TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP +QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ +PEKDAK----------------- +>[subseq from] Beta-lactamase n=1 Tax=Alcanivorax sp. EA2 TaxID=2183984 RepID=A0A3D9IKD4_9GAMM +--ALGHRCQEWERRHGGRIGVAVWNLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD +QGQESLDRRLLVSRKDLVGWSPVTEKRTGEGMTVAELCEAAVAWSDNGAANLLVKGFGGP +GALTEFLRESGDPVTRLDRLEPELNGYGGADESDTTSPGAMLDTLYRLLFGEVLSAHGRA +QLAAWMIVNKTGDRRLRAGFPANWLVADKTGTSGLGYSNDVGVAWSPARGAVLVTVYCEM +PKAEAEARDRIIAEVAEMVS--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Mycobacterium TaxID=2642494 RepID=UPI0009925737 +-----TELASLEKDFGGRIGVYALDTGSGATL-GHRANERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYAQSDLMEWAPVTSQHVAEGMTVAELCDATLRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLALDEGLDAQGRD +LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP +DDPKSTQGKPTIAAATRIALKAf +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium neoaurum TaxID=1795 RepID=A0A024QNI4_MYCNE +--ALPERIRDLEARHNAFIGVFGMNLDSGMSV-RHRAEEPFAMCSTFKTYAAAAVLRRVA +EGELSLDKPVFVDPAGILPNSPVTEERAGGQMTLAELCQAALQRSDNLAANLLLATLGGP +RAITDFARSIGDDKTRLDRWETDLNSAIPGDPRDTSTPEALGTGYRNLLAGDALPPAQRD +LLDGWMRANQT--SSMRAGLPPDWTTADKTGSGDYATTNDVGIAYGPGGSRVLLSIMTRT +QSPDAEGLRPVIGEIAALVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F5B32F9 +--TAHAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAVLWPPSRAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces ipomoeae TaxID=103232 RepID=A0A540PZV3_9ACTN +---TAAEFRSLEKEFDARLGVYALDTGTGRSV-GYQADDRFAYASTFKALAVGAILRKYG +--TDGIDKVVRFSRDDVVADSPVSENFVETGMTLRGLCAATLWYSDNTAVNLLLDELGGP +DGLERVLERLGDDVTEMDRYEPDMSDGIPGDIRDTSTPRAMAGSLRAFLLGDALKRDERR +LLRQWMTTNMTGRNLIRAGVPDDWEVADKSGSAGYGGRNNIAVVWPSDGNPIVMAVLSTR +DKQGAERRDALIAKAATVAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. URHD0025 TaxID=1298864 RepID=UPI000401E568 +----DGQIAELERRDNALIGLYAANLDSGRTI-THRPDEMFAMCSTFKGYAAARVLQMVG +RGQLSLDNRVFVDRNAIVPNSPVTETHAGAEMTLAQLCQAALQRSDNTAGNLLLKTIDGP +GGITAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAVLAGDALSPPQRR +QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS +QADDPKADN-------------- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. GA-1199 TaxID=1772287 RepID=A0A101BM29_9MYCO +---IADRLGEMERRQNALIGVFATDLGTGRTI-AHRAQDPFAMCSTFKTYAAARVLQKAE +RGELALTDRVTIEPGDIVPNSPVTEAHVGQTMTLAQLCQAALQRSDNAAANWLLRVIGGP +SGVTDFARSIGDQRSRLDRWEIELNAAVPGDPRDTTTPEAIAGGYRSILTGNVLAEPQRR +QLEDWMRANQT--SSVRPVLPPGWATADKTGSGDYASTNDVGIAYGPAGERLLLAIMTRT +AAPDAPNDRQLVGEVASALVA-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBA3_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD +AGRVSLDTRVPIAAKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +PALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Leifsonia TaxID=2663824 RepID=UPI000375FEDB +--AAARALAELESQYGATLGVYAVDTGTGRSV-GYRQDDRFAYASTSKVLLAGAVLARSS +--DEQLDAVVPYTSDDLVSYSPITETMAGAGMPLRDVIAAALQKSDNTAANLLFRQLGGP +AELEKSLRALGDETTEVERTEPALNEAAPGDPRDTSTPRALAADLRAYALGEELPANRRK +LLVDDMTGNATGDPLIRAGAPTGWTVSDKSGAASYGTRNDIAVLTAPGHAPVVMVVLSRK +ADKDAAYDNALVADTAKVL---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces harbinensis TaxID=1176198 RepID=A0A1I6QZ27_9ACTN +-----GEFARLEDAYDARLGVYALDTGSGEEI-GYREDERFAYASTFKALLCGAVLEEYG +--LAGMDEVIPYGEEDLLPNSPITEERLAEGMSKSDLCDATVRYSDNAAANLLWDTIGGP +AGLQERLAGLGDDVTRMERWETELNEAVPGDERDTTTPEAFAGNLAGYVLGEVLPEPERA +QLTEWLVTNTTGDELIRVGVGEGWTVGDKTGGGGHGTRNDIAVLWPDSGPPLVLAVFSTR +EEPDADWDNALIAEAASVAV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SAA1_KLEPN +-----------------------MDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIFWR- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=A0A132F6N5_9BURK +--AAQSDLAALEKASNGRLGVAALDTSNGARV-AHHARERFPLCGTYAVVAAAAVLARGS +LDATLLPRRILYRRYDVVAGSPVTENHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTTFRLDHWEPELNAAAPGDERDTSTPVAMVDMLQRLLLGDLLREPQRA +QLIEWMVGGARGAAGIAAGVPPGWRVADKAGTGRYGTTSDVAVVWPPSRAPLVMAVSFTQ +PRADAAARADVVASAARIVAN-- +>[subseq from] Beta-lactamase OXY-2 n=2 Tax=Burkholderia TaxID=32008 RepID=A0A088UZM8_9BURK +--AAQSDLAALEKASNGRLGVAALDTSNGARV-AHHARERFPLCGTYAVVAAAAVLARGS +LDATLLPRRILYRRYDVVAGSPVTENHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTTFRLDHWEPELNAAAPGDERDTSTPVAMVDMLQRLLLGDLLREPQRA +QLIEWMVGGARGAAGIAAGVPPGWRVADKAGTGRYGTTSDVAVVWPPSRAPLVMAVSFTQ +PRADAAARADVVASAARIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Tistrella mobilis TaxID=171437 RepID=A0A162LGU4_9PROT +--RLADTVSRIEDQLDARIGLVLHDTGRNWRW-GHRADERFLMNSTVKMPICGAILAGVD +AGRISLDETLPIRRADLVSHAPVTRPRVGQAMSIADLCFATLDQSDNPAANLLITRLGGP +AGVTQFFRSIGDPVSRLDRLEPGLNSAPAGDARDTTTPAAMAATMETLLLGTSLSPASRA +QLTEWMRHGGVTGALLRKSAPADWQIADKSGAGDN-TRNLVALITPPGRAPWIAAIYLGD +AETDFATRNKALAEIGAAVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Kibdelosporangium aridum TaxID=2030 RepID=A0A1Y5XUI0_KIBAR +------DFKALEARFDARLGVYAVDVTTGKSV-AYRENERFAICSVFKAYAAGALLKAHP +LSSGFFTQTIRFTQAEVVANSPVTSTRVTTGMTVAELCEAAITKSDNTAGNQMLKLLGGP +TKLTDFARSIGDPVTRLDRWETELNVVPRGTEQDTTTPIAIAGAYRDLVVGNVLGEPERK +QLKDWLIANTTGDARIRAGLPSGWVTGDKTGTGSFAAANDVAVTWPSPEKPIVIAILTDK +ADENAKYDNALIAEATKVAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. SAI-095 TaxID=2597743 RepID=UPI00135939D5 +------AIAALEQKHQRRLGVWAKNMRTGRVI-EHRADERFPMLSTFKTLLAASILRDHP +--ARTLQQRLTWEAADVVINSPITSLTVRNGLTVAQLAEATITRSDNTAANELLHLIGGP +AGITRFARSLGDSVTRLDRWEPDLNSAIPGDPRDTTSPRAIAQTYTKLVLGDALDRADRD +QLLTWMLANQSTVTRFGAGVPAGWRLADKTGGGDYASRNDVGVTWTPDGAPIVIAALTRS +DNPTAAPLDTPLADIAATVC--- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter nitrogenifigens DSM 23921 = LMG 23498 TaxID=1120919 RepID=A0A511X6X8_9PROT +----PQAIATYERESRGHIGVYAENLATGRKL-LWRADERFVMCSTFKASLAACVLRRVD +RGQEKLDRIIAYTKADVPDYAPVARENLARGMTVAEMCQAAVEQSDNTCATLLLSSIGGP +AALTAFWRSIGDTQTRLEDPEPYLNRTPPGGVRDTTTPSSMAKILQRVALGDVLSDSSRA +LLTGWLVGCQTGANRLRAGLPKTWRVGDKTGNNAKDAAGDIAVLWPKPDAPIIVAVYTRG +GTPTDAQLASAFAGVGALVAE-- +>[subseq from] Beta-lactamase n=2 Tax=Citrobacter koseri TaxID=545 RepID=Q7WZT6_CITKO +--------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD +RKALALSASTQFEPSQLVEYSPITEKHVAPDMNWAQLCSAAVSYSDNTAANLIARKLNGP +QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAKTLNTLLLGNVLQPSSRE +QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ +TPATMAQRDAAIVRIGESLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Motilibacter sp. E257 TaxID=2714956 RepID=UPI00140A750F +---ADEEFGELEDAYQARLGVYAVDTGTGREL-TYRADERFAFASTVKALAAGALLQQLS +--DAELDATVEYDTADLVPHSPVTERHVVTNLPWRTVLAAALQQSENTAANLMFARLGGP +AGLQQALRALGDRVTRSDRVEPALNSAVPGDVRDTTTARAIAHDLRELLLGDALQADRRA +LLRAWMTTNTTGGPYVRAGLPAGWEAADKTGSGGHGTRNDIAVVWPPGGAPYVIALMSDR +GVEGARSEDRLLADATRVALE-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio rotiferianus TaxID=190895 RepID=A0A510IBU6_9VIBR +--KLNEDLAAIEQHIGGRIGVSVWDTQNDEHW-DYRGDERFPMMSTFKTLACATMLSEMD +SEKLDKNATAKVEERNIVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +NGVTRFLRSIGDGATRLDRFEPRLNEAKPGDKQDTTTPNAIVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSESLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPIYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B063F +--AAQAQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGSANSVAGIRAGVPFDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas halophila TaxID=29573 RepID=UPI0011BDF169 +--DLDQRLGELERADDDRVGVALMNVATGAVA-SHRGDERFLFNSTGKFFIAAAVLARVD +EGSETLDRRVVIEEGDLGGWTPITEKRLGEPLTLAELCQAAVAWSDNAAANALIESVGGP +EAVTAFLREIGDDTTRLDRLEPELNTDHAGDERDTTTPLAMMTTLRTLLLGDVLSPSLRH +QLASWMIEGKTGDARLRAGMPSSWLVGEKTGTNGVGNANDIGIAWPGDRGAVIAVAYTRM +PSATAEQRDETIAAVGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium kubicae TaxID=120959 RepID=UPI0007FF50E8 +----SDRIDELESQYHAFAGVYAQDLDSGHTV-THRADDPFAMCSTFKAYAAGRVLQKAQ +GGELDLDQATFIDPNELQPNSPVTAPHAGHSMPLAQLCAAALQRSDNTAANLLLQAIGGP +PAITEFARSIGDDRTRLDRWEVELNTAIPGDPRDTSTPRALGAGIQNLLAGTVLAPPQRR +QLETWMRGNVT--STMRAGLPPGWTTADKTGSGDYGSTNDVGIAYGPNGQRVLLAIMTRS +QAPDADALQPLIADVTRAVL--- +>[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010834254 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVALCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGI-------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas sp. NML171590 TaxID=2527958 RepID=A0A4Q9TBP7_9GAMM +-----KDFAALEQVSGGRLGVTLLEVGTGRRM-GRRQDERFPMCSTFKALLAAHVLSLAE +AGALSLDERLPIRQAQLLSWAPESERHVGKDLTVRDLCRAAVTNSDNTAANLLLARAGGP +PALTAFLRRQGDAVTRSDRYEPEMNNFAPDDPRDTTSPAAVAASLARFAVGDGLSKASRA +QYADWLIDNQTGDDCLRAGLGKRWRVGDKTGNNGRDTRNDLAVLWPLGGTPWVLVALLQG +ARVDADQRDAVLARVGALA---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Methylobacterium sp. WL6 TaxID=2603901 RepID=A0A5C8W7Q6_9RHIZ +------RIGALEARLGGRVGVAFRD-ATGVFL-GHRADEAFALCSTFKVLAAAAILARVA +AGRETLDRRIAYGADDLQSYAPVTRSALDAAMTVGGLCAAAIVRSDNTAANLLLDALGGP +AALTAWLRGQGDAVTRLDRTEPTLNTALPGDPRDTTSPAAITRTLDRCLLGDALAPPHRA +RLEAWMVACETGGAKLRAGLPPAWPVGDKTGSGDNATSNVVAILHPPGRAPILAGVFLTG +SEAPPAARDAAHAEIGRILAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Phycicoccus jejuensis TaxID=367299 RepID=UPI00055D7D88 +----DRAFAALERVHDATLGVTAIDTATGRTV-SWRSGTRFPFASTNKTFIAAAVLDRSS +--DADLDEVVRYTREDLLEYAPVTSRFVDTGMTVRELLDAALRFSDNTAANLLVERLGGP +GAVQAWLREHGDRVTRVDRVEPELNEALPGDPRDTTTPAQFARGLRDVVLGSDLAVGDRT +LLRNLMLGCTTGDATVRAGVDPAWPVADKTGTGEYGVRDDIAVVYPAGRAPVVVAVFTRQ +DTPDAEPDNALVAAATREAVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID4985 TaxID=2690292 RepID=UPI00136E783F +--HVTAQLRSLEREYDARLGVYARNTRTGRTV-AYRAGEPFAMCSLFKAFAAAAVLRDHG +DGRTGLDEVIHFPPADILSNSEHSKGYLETGIPVRDACALAIQYSDNTAGNLMLRRIGGP +AGLTRFFRSLGDEVSRLDRWETDLNTAIPGDPRDTTTPYAIGRGLERLTLGNALSGADRR +QLVAWLSGNTTSTRRFRAGLPADWTLADKTGTGSYASAHDLGIAWTTRRTPVVLAVLTTK +AERDAPVDESLIERTARLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A63BEE +-----NELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL +SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDSAPIVMAVLTVP +EDPTSTKGKPTIAAAARIVLRAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB95_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIdGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075814B8 +--AAQAQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLIGSANSVAGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. OK519 TaxID=2135729 RepID=A0A2T5KRI3_9NOCA +----DSEFAALEEQFDARLGVYAVDTGTGREI-EWRGDERFAYASTIKALAAAALLDDVG +--TAGLAKTVEVGASDIIKHSPVTETRVGQTMTLDEICEAALTQSDNAAANFIFAELGGP +QAFDARLDELGDAGTTVSRIEPDLNEALPGDARDTTTPRASANNLREYVFGDALDDEEKT +TLTDWMKASRTGDALVRAQLPEDWTVGDKSGGGMYGSRGDLAVVWPTDGRPIVISVLSSR +DEREADYDDRLIAGAAAAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075258C2 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSSVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces ipomoeae 91-03 TaxID=698759 RepID=L1L8R3_9ACTN +---TAAEFRSLEKEFDARLGVYALDTGTGRSV-GYQADDRFAYASTFKALAVGAILRKYG +--TDGIDKVVRFSRDDVVADSPVSENFVETGMTLRGLCAATLWYSDNTAVNLLLDELGGP +DGLERVLERLGDDVTEMDRYEPDMSDGIPGDIRDTSTPRAMAGSLRAFLLGDALKRNERR +LLRQWMTTNMTGRNLIRAGVPDDWEVADKSGSAGYGGRNNIAVVWPSDGNPIVMAVLSTR +DKQGAERRDALIAKAATVAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces swartbergensis TaxID=487165 RepID=UPI000A388583 +------RLADLEREYGARVGVYALATGTGASA-IHRADERFAFCSVFKALAAAAVLHHRS +--LDGLDRRVTYTRDDLRSTTPITAKHVATGMTLRQLCDAAVRHSDGTAGNLLMRDLGGP +AKLTAYLRDLGDSVSRMNHYEPELHDVPPEDPSDTTTPRAIAADFHKLLLGTALPAGERA +LLTDWLSHNATGARRIRAGLPKGWQVADKTGTGNYGRANDIAIVRPPRTEPLVLAVMTDR +PGYDAAPSDALIAEATAR----- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. uw30 TaxID=1828179 RepID=UPI0011CE17F9 +----ADRFRELERQHGARLGVFAHNVRTKRTV-THRADELFPMCSLFKTLASAAVVRDLD +HDGEFLARRIHYTEADLPKGSDKTREHLAEGMTVAELCEVAITYSDNGAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSARAIGRTYGRLVLDDALNGPDRG +LLTRWLLSNTTSGKRFRAGLPPTWTVADKTGSGSYGTTNNVGIAWTPDGAPVVLAVLSTK +PAQDAAWDDALVAETARLL---- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium conceptionense TaxID=451644 RepID=A0A0J8UC08_9MYCO +---IDDQLAELERRDNVLIGLYASNLDSGRRI-THRADQMFAMCSTFKGYAAARVLQMAE +RGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPSQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS +QAHDAENLRPLIGELTALV---- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium conceptionense TaxID=451644 RepID=A0A0U1DTP3_9MYCO +---IDDQLAELERRDNVLIGLYASNLDSGRRI-THRADQMFAMCSTFKGYAAARVLQMAE +RGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPSQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS +QAHDAENLRPLIGELTALV---- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. OF1 TaxID=2213162 RepID=A0A5P0Z151_9ACTN +----SRRLRALEREHDARIGVFAYDTGTRRRV-LHRADERFPMCSVFKTFAAAAVLRDLD +RDGDFLAKRIRYSRQEADDYAPVTGRNIARGMTVGELCGAAVSESDNAAANLLLRELGGP +RSITRFCRSVGDDVSRLDRWEPELNSAEPWRVTDTSSPRALGRSYARLVLGDALEPGDRT +RLTDWLLANTTNGERFRAGLPADWLLGDKTGAGSYGTNNDAGVAWPPGRAPLVLVVLTTK +FEPDAAPDNTLVRRTAELLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI00075E2457 +----QAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAVLARGA +LDASLLPRRILYRRYEIVSGSPITESRVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PEATAAARADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=UPI0008A99EFE +-----SELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYAQSDLMEWAPITSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD +LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP +DDPKSTQGKPTIAAATRIALKAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000668783C +htXAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMIGGARGATGIAAGAPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura rifamycini TaxID=31962 RepID=UPI0003F56BAC +--EVGKRLHRLEAERNLRIGAYAIDPATGAFV-SHRADERFPYTSTFKAIACGGVLQKAR +TDPGLMERVIHYTEDDLVEWSPVTKDHVDTGMTVSALCDAAITQSDNTAGNLVMKQLGGP +AGLTRFFRSLGDGISRADRWETALNDWKPGERRDTTVPSVWAANLHKLTVGDVLVPEDRE +QLIAWMKANTTGDKRIRAGLPDSWTIGDKTGSGGYGNANDIAVAWPPGRDPLVMVILTTA +KKVDAEADDAAVAETAAILA--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio alfacsensis TaxID=1074311 RepID=A0A347UWX4_9VIBR +-tKLNEDLASIEQHISGRLGVSVWDTQTDQRW-DYRGDERFPMMSTFKTLACATMLHAMD +NDKLDRNATAKVEERNVVVWSPVMDRMVGQTTRIEHACEATMLMSDNTATNIVLRSVGGP +KNVTLFLRSIGDKATRLDRFEPRVNEAKPGDSQDTTTPNAMVNTLHTLLEGDSLSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQIIAQISQLVLDEy +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces hainanensis TaxID=402648 RepID=A0A4R4TAJ5_9ACTN +--DTEREFAALEREFDARLGVYALDTGTGREV-AYRADDRFAFASTFKSLAVGAALQRFG +--VEGMDEVVEYAADDIVPNSPVTENFVETGMSLRELSAATLWYSDNTAANLLFDALDGP +EGLEAALEELGDDVTEMDRYEPELSDGVPGDIRDTSTPRALAGSLRAYLLGDALEREERE +LLTTWMATNTTGETLIDAGVPDDWTVADKSGTAGYGGRNDIAVLWPEDGNPIVMAVLSSR +DQEGATRDDALIARAATAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=UPI0008A83CDA +-----SELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVTAILHRRL +SEPGLLDKRIQYAQSDLMEWAPITSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEDQLN--VPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD +LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP +DDPKSTQGKPTIAAATRIALKAf +>[subseq from] Beta-lactamase n=1 Tax=Microbispora sp. ATCC PTA-5024 TaxID=316330 RepID=W2EHT3_9ACTN +---VRRELRALEASFRGRIGAYAVDTATGATV-SYRPDERFPLLSTFKALAAAAVLHTAR +TDPGLMSRVVHWTAAEVKPNSPITAGHVEDGLTVARLCEAAVTRSDNTAGNILLKRVGGP +AGLTRYLRSIGDGTTRLDRWETGLNVWSPGERRDTTTPAAVVRDLRALTVGDALTPQDKD +RLNGWLRATRTGDARIRAGLPATWLVGDKTGTGSYGTANDIAVVRPGTGAPIVMAVYTTR +KAAGAPADEKVVAETAAVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix sp. NRRL B-16348 TaxID=1415542 RepID=UPI0009EAEEB5 +------HLIELERKFDARLGVYAVATGTGTTL-AYRADERFAFCSTFKGLAAAAVLHRHP +--LSHLDTVVTYTERDLMASSAITRQHVATGMTVRQVCDAAVRHSDGTAGNLLLRDLGGP +AGLTAYVRGLGDTVTRSDRVEPDLTTAVPGDPRDTTSPRAIGVDYREIVLGDALEPDKRA +FLRDLLERNATGTQRVRAGVPQGWTVADKTGTGDYGTVNDIAVVWPPNAAPLLISIMSSK +AAADDGYDQALLAEAAAYAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A7993B +-----NELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL +SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVSRMDRTEVQLK--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP +EDPTSTKGKPTIAAAARIVLRAf +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase FRI-2 n=1 Tax=Enterobacter asburiae TaxID=61645 RepID=A0A1Z1CLH6_ENTAS +-----EQMRELEASFGGRIGVYILNTKNGKEF-SYRQDERFPLCSSFKAFLAASVLKKTQ +DKSVSLDDMMEYSGRVMEKHSPVSEKYRKTGASVRTLAKAAIQYSDNGASNLLMERIGGP +EGLTAFMRSTGDTDFRLDRWELELNSAIPGDERDTSTPKAVAMSLKNIAFGSVLDAKNKS +LLQEWLKGNTTGNARIRAAVPDKWDVGDKTGTCGYGTANDVAILWPDANSPAVMAVYTTR +PNQNDKHDEAVIKDSAKIAIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=UPI000C9A2E5E +--DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD +RGTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP +EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTASPRSVLSTLHAALSGTMLSGSSSA +QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE +TDADFSRRNQAISDIGRAMI--- +>[subseq from] Beta-lactamase n=2 Tax=Tistrella TaxID=171436 RepID=A0A3B9ITI8_9PROT +--RLADTVSRIEDQLDARIGLVLHDTGRGWRW-GHRADERFLMNSTVKMPICGAILAGVD +AGRISLNETLPIRRADLVSHAPVTRPRVGQAMSIADLCFATLDQSDNPAANLLITRLGGP +AGVTQFFRSIGDPVSRLDRLEPGLNSAPAGDPRDTTTPAAMAATMETLLLGTGLTPASRA +QLTEWMRHGGVTGALLRKSAPADWQIADKSGAGDN-SRNLVALITPPGRAPWIAAIYLGD +AETDFATRNKALAEIGAAVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A3C0X538_9GAMM +------DFAALEKASGGRLGVTVLDTGSGRRHgGHRQDERFPMCSTFKSMLVAHILSLAD +AGRLSLDTRVPITERDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP +AALTAFLRAQGDTVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGDGLLPPSRL +QFADWLVDNQTGDACLRAGLGPRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG +ASVDEAQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=UPI000C99BA5A +--DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD +RGTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP +EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTASPRSVLSTLHAALSGTMLSGSSSA +QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE +TNADFSRRNQAISDIGRAMI--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI00001125EC +---IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYVAARVLQMAE +HGEISLDNRVFVDADALVPNSPVTEARAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS +QAHDAENLRPLIGELTALV---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0009822EB5 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGA +LDASLLPRRILYRRYEIVSGSPITESHVDAGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A106Q6G5_9BURK +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLIGSANSVAGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. 115 TaxID=1162282 RepID=I4VJN5_9GAMM +--AIAGELATLERQHGGRLGVAMLDIGSGRHA-GHRAGERFLLCSTGKLLVVGAVLARVD +RGEEQLSRRIVFGPDVILEWAPVTRKHVGAPMTVAELCHAALTISDNTAMNLLLKGMGGP +VAATRFVRSLGDDITRLDRHESELN--VPDKDLDTTTPEAMLASMRKLLLGNVLSASSRA +QLIDWLRHNTTGETQLRAGMPANWQVGDKTGSGHT-QTNDVAIAWPPGRQPLLVTAYYEG +PADQGDMRKAVLAHVGKLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC 06738 TaxID=2203210 RepID=A0A3Q8UWV4_9ACTN +-qRATREFKELERAHDARLGVYAVDTRTGREV-AYRAGERFAFASTVKAFEAGAVLRQRK +--LAGLEKEITYDRSDLVANSPITEKHVDDGMTLGELCDAAVRYSDNAAANLLFEEIGGP +KALQSFLRETGDDTSRMERIEPALSDWEPDAVRDTSTPRALAGNLRAFVLGDVLDTPERA +RLAEWLRTNTTGDETIRAGVPKDWEVGDKTGTAAFGGRNDIAVVWRPDAAPLVMAVLSHG +TDRDAEPDDELIAKAAAVVSD-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium obuense TaxID=1807 RepID=A0A0M2JWH4_9MYCO +-----DRLAALGRRHNARIGVYAVDLGSDRTV-EVGADDMLAMCSTFKAYASAAVLQRAQ +QGRLALTDAVLVGRSDIREHSPVTEPRVGSTMTLAELCQAALQQSDNAAGNLLLRTLGGP +SAITDFARSIGDDRTRLDRWETELNTAIPGDPRDTSTPRALGSGFRAVLTGDVLDGAHRQ +MLEDWMRANQT--SSMRAGLPGGWATADKTGSGGYGTTNDVGIAYGPQGQRWLLSIMTRS +ATPDADSLRPLIGEIAAAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Vibrio TaxID=2614977 RepID=UPI000C8248FB +-----ESIEQIESRVSGRIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDHE +NEGLDLESKVGVNSDELIAWSPVTKAFVGKEISLRGACAATMAMSDNTAANIVLASIGGP +NGLTEFLRSTGDRKTRLDHIEPDLNHARPGDERDTTTPNTMVKTLNKLLYGSALSEESKA +QLKTWMIDNKVSDGMIRSILPDGWKVADRSGAGAYGSRAITAIVWSENRAPLIISISLTE +TELTIPERDTVINEIGELIFDEy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007576F52 +--AAQAQLDALEQASNGRLGVAALDTASGARI-SHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGSANSVAGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Labrenzia sp. CE80 TaxID=1788986 RepID=UPI00129B1204 +-----QQAIEIEKRHDARIGIAVLDDKTGTAW-SYKGDIRFPLNSTFKAFACAALLAQVD +DGTTDPNKSVQIKRADIAPYSPVTKKQIGKTMSYLGLCNAAVTISDNTAANYILKEIGGP +AGLSAFLRKLGDTETRLDRWEPELNNVPAGELRDTTTPIAAATTLKTLLLGGPLSANSRK +QLTDWLVANKVGDTLLRAGLPQRWKIGDKTGADAKKSRGDIAVIWPRPDRAVFVAVYLDE +AHVDMSRRNAAIAEIGRALTK-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0003616D4E +---TTARLRELERTHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD +RDGEVLEKVIHYTEADCVSDSPVTDTHLASGLSVARLCDAAIGDSDNTAGNLLLRELGGP +QAVTRFARSLGDRVTRLDRWEPVLNSAEPGRVTDTTTPSALARDYARLVLGNALEPRDRE +RLTYWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYASCNDVGVAWTPEGVPVVLAVLTTK +PASDAAGDHPLVRDAAEALA--- +>[subseq from] Beta-lactamase n=1 Tax=Psychromicrobium lacuslunae TaxID=1618207 RepID=A0A0D4C4C1_9MICC +--------------------------------------------ATFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Plantactinospora sp. CNZ320 TaxID=2035246 RepID=A0A2N3SDD6_9ACTN +-------LIRLEREFDARLGVYALATGTGNVV-AHRADERFAFCSTFKGLAAAAVLARNP +--LSHLDTVVRYDRSDLTANAVVTSRHVDRGMTIRQLCDAAVRHSDGTAGNLLVRDLGGP +AQLTAYARSLGDTVTRMDRIEPAITQATPGDPRDTTSPRAIGTDYQKILLGDALVPEKRA +FLRDLLERNATGARRIRAGVPKGWTVADKTGTGGYGTVNDIGVVWPPGASPLVIAIMSSK +ASRNADHDQAIIAKATEYAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075834EB +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGALERA +QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptacidiphilus anmyonensis TaxID=405782 RepID=UPI0005AA6C13 +---LHGRLRALEQEHSARLGVFAYEPGTGRAV-LYRADELFAVCSTWKTIGVAAVLRDLD +RDGEFLAHVVHYTQQDATAYAPITGDNVAHGMTVADLCAAAVDYSDNGAANLLLRQLGGP +QAVTRFCRSVGDRVTRLDRWEPALNSAEPGRVTDTSTPRALGLTYARLVLGDALDPADRE +RLTGWLLANTTSGQRFRAGLPKDWTVADKTGTGQYGTTNDVGIAWPLRRGPVVMSVLSTK +RDAAAAADEPLIAQAAQLLATAf +>[subseq from] Beta-lactamase n=1 Tax=Comamonas thiooxydans TaxID=363952 RepID=A0A0K6HP48_9BURK +--TLSDELAALEIQAQGRFGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ +RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVLVSDNTAANVLLEASGGP +AALTQWLRELGDGTTRLDRNEPSLNTALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA +LLQQWLVDSRTGDKRVRAGMPGDWKVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG +SPLDGAGREAVLARAGEAIK--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI00051821CD +----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD +HDGSQLSRVIRYTEADVTKHAPVTKDHIDTGMTIRDLCDATIRYSDNCAANLLLRELGGP +TAVTRFCRSLGDPVTRLDRWEPELNSAEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA +LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDGAPVLLTALTHK +PSPTAPGDTPLIIKLATV----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB01249 TaxID=1703929 RepID=A0A1Q5DX63_9ACTN +---TTARLRELERTHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD +RDGEVLEKVIHYTEADCVSDSPVTDTHIASGLSVARLCDAAIGDSDNTAGNLLLRELGGP +QAVTRFARSLGDRVTRLDRWEPVLNSAEPGRVTDTTTPSALARDYARLVLGNALEPRDRE +RLTYWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYASCNDVGVAWTPEGVPVVLAVLTTK +PASDAAGDHPLVRDAAEALA--- +>[subseq from] class A beta-lactamase n=1 Tax=Saccharopolyspora sp. ASAGF58 TaxID=2719023 RepID=UPI00143FCA02 +-----PAFADLERRYDARLGLFAVNVHTGQFL-GHRAGERFAMCSTFKTYAAAALLREHG +LDSGYFDKMIHYTEADLVDGSPITKPNAGTGMMVHELCAAAITRSDNTAANLLLAELGGP +ATIAPFARSIGDGSTRLDRWEPDLNMAIPGDERDTTTPAGIAAGYRALVVGDALRGPEHD +RLTGWLFANTTGGKRIRAGLPPTWRTGDKTGTGDYASGNDVAVTWTDKGHPIVIAVLTSR +PRKGDEVNNGLHVDTARVVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. BK438 TaxID=2512151 RepID=A0A4V2SST3_9ACTN +---TTARLRELERAHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD +RDGEVLEKVVHYTEADCVSDSPVTDTHLVSGLSVARLCDAAIGDSDNTAANLLLRELGGP +AAVTRFARSLGDRVTRLDRWEPLLNSAEPGRVTDTTTPSALARDYARLVLGNVLERRDRK +RLTYWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYGSCNDVGVAWTPEGVPVVLAVLTTK +PASDAAGDHPLVRDVAEALA--- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio TaxID=662 RepID=UPI00021A91E7 +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGTRSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDVIVKIGRSIFEVy +>[subseq from] class A beta-lactamase n=1 Tax=Alcanivorax xenomutans TaxID=1094342 RepID=UPI000BD71558 +--ALGHRCQEWERRHGGRIGVAVWNLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD +QGQESLDRRLLVSRKDLVGWSPVTEKRTGEGMTVAELCEAAVAWSDNGAANLLVKGFGGP +GALTEFLRESGDPVTRLDRLEPELNGYGGADESDTTSPGAMLDTLYRLLFGEVLSAHGRA +QLAAWMIVNKTGDRRLRAGFPANWLVADKTGTSGLGYSNDIGVAWSPARGAVLVTVYCEM +PKAEAEARDRIIAEVAEMV---- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteriaceae TaxID=1762 RepID=UPI0007A0FBEA +------ELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYAQSDLMEWAPITSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD +LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP +DDPKSTQGKPTIAAATRIALKAf +>[subseq from] class A beta-lactamase n=1 Tax=Aurantimonas coralicida TaxID=182270 RepID=UPI0004A269E6 +--RLAETVRGLEERLDARIGVFIRDSGSDWQW-GHREDERFLMASTFKSVLCGAVLEQAE +QGALALDEPVEIRAADILSYAPVTETRQGGTMTIGELCLATTDMSDNTAANLLLARLGGP +QAVTAFLRGIGDGVTRLDRTEPDLNIFAPGDPRDTTSPKAMATSWESMLVGDGLRPDSRQ +QLREWMRLGGVTGKLIRASTPRDWEVVDKSGGGRTHTRNLVAMITPPGRAPVFVAIYLSD +SPADFSTRNAAVAEIGAAIV--- +>[subseq from] Beta-lactamase n=1 Tax=Comamonas sp. AG1104 TaxID=2183900 RepID=A0A370EY75_9BURK +--TLSDELAALEIQSQGRFGLHVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARVLYLAQ +RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVLVSDNTAANVLLEASGGP +AALTQWLRELGDGTTRLDRNEPSLNTALAGDERDTTTPQAMVQSLQKLLLGDVLEGYARA +LLQQWLVDSRTGDKRVRAGMPGDWKVGGKTGSGERGTACDTLIVWPTEQAPLLVTAYLTG +SQLDGAGREAVLARAGEAVKR-- +>[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces sp. SAI-097 TaxID=2485145 RepID=A0A3N1DT91_9ACTN +----SRSLAALERTHGARLGVFAWNTVSDRIV-RHRGDELFPACSVSKTPAVAAVLRDLD +RDGEFLRKVIRYGADDVDRYAPVTGENLANGMSVSDLCAVAITHSDNTAMNLILEELGGP +TAVTRFCRSIGDTVTRLDRWEPELNSAEPGRVTDTTSPLAMGKTYARLVLTGTLGTADRD +RLKGWLLANTTGDNRLKAGLPASWTVAEKTGTGDYGTTNDVGVAWTDKGEPVVLAVLSTK +ADAEAAADEPLLAEAAWVIAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. NRF60-BP8 TaxID=1637853 RepID=UPI00075D92FC +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKSAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNQATPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGNGGFGTTTDVAVLWPPSRAPIVMAVSFTQ +PEAAAAARADVVAAAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Alcanivorax TaxID=59753 RepID=UPI00047DDBC9 +--ALGHRCQEWERRHGGRIGVAVWNLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD +QGQESLDRRLLVSRKDLVGWSPVTEKRTGEGMTVAELCEAAVAWSDNGAANLLVKGFGGP +GALTEFLRESGDPVTRLDRLEPELNGYGGADESDTTSPGAMLDTLYRLLFGEVLSAHGRA +QLAAWMIVNKTGDRRLRAGFPANWLVADKTGTSGLGYSNDVGVAWSPARGAVLVTVYCEM +PKAEAEARDRIIAEVAEMV---- +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X4S6_9BACT +--SARKQLNKLEHSLDGKIGIFAMNTANQQTI-HYRSKERFPIQSTFKLMVVAAILKKSA +TDPELLQKKIFYTKNDLVTWSPITEKRIDSGMSILELCDATMKYSDNTATNLLMKQVGGP +AVITDFAHSLGDSVFNVLHYEAELNSN-PNSTDDTSTPENMGINLKKIAFNPILPSSYIH +LLLNWMKENTTGDAQIRAGVPKEWVVADKTGSSSFGTSNDIGIIWPTGCDPIIIAIYTVQ +NKEDATKRNDILKDATRTVINEf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WXP4_9BACT +--SARKQLNKLEHSLDGKIGIFAMNTANQQTI-HYRSKERFPIQSTFKLMVVAAILKKSA +TDPELLQKKIFYTKNDLVTWSPITEKRIDSGMSILELCDATMKYSDNTATNLLMKQVGGP +AVITDFAHSLGDSVFNVLHYEAELNSN-PNSTDDTSTPENMGINLKKIAFNPILPSSYIH +LLLNWMKENTTGDAQIRAGVPKEWVVADKTGSSSFGTSNDIGIIWPTGCDPIIIAIYTVQ +NKEDATKRNDILKDATRTVINEf +>[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. AND4 TaxID=314289 RepID=A8T2U3_9VIBR +--KLNEAISAIEEHISGRIGVSVWDTQTDERW-DYRGDERFPMMSTFKTLACATMLSNMD +NETLDKNATAKVEKHNMVVWSPVMDRMAGQTIRIEHACEAAMLMSDNTAANIVLRSIDGP +QGVTKFLRSIGDKITRLDRFEPTLNEANPGDKQDTTTPNAMVNTLNTLLESDALSYESRI +QLKIWMQDNKVSDSLIRSVLPKGWSIADRSGAGGFGSRGITAMVWKENHRPIYISIYITE +TDLSLQARDQVIAQISQLILDGy +>[subseq from] Beta-lactamase n=1 Tax=Leifsonia aquatica ATCC 14665 TaxID=1358026 RepID=U2RTW4_LEIAQ +--STQRAFAELERTHGATLGVTAIDTGNGRTV-AYRGGERFPFASSNKTFIAAALLGRSS +--DADLDQVVHYTSADLLDYAPITSRFVDTGMTVRELIDAMLRFSDNTAANLLVARLGGP +DAVEQWLRGIGDRTTNVDRVEPDLNEALPGDARDTTTPAQFASDLRAVLLGSALETKDRT +LLRNTMLDNTTGDDTIRAGVDPAWPVADKTGTGEYGVRDDIAVVYPVGRAPIVVVTLSRK +ATPDATPDNALLAAATKTAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00036EE5D4 +-----NELASLEKDFVGRIGVYALDTGSGDTV-SHRTDERFLMCSTVKTFIVSAILHRSL +SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP +EDPTSTKGKPTIAAAARIVLRAf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-146 TaxID=1463884 RepID=UPI00069016F0 +------RLADLEREYGARVGVYALATGTGATV-VHRAGERFAFCSTFKALAAAAVLHHRS +--AGGLDRRVTYTEADLCSTAPVTGKHVATGMTLRELCDAAVRFSDGTAGNLLMRDIGGP +AGLTAYLRGLGDTTSRMDHYEPELHDVPPDDPADTTTPQAIATDFRELLLGTALPVRERR +LLMGWLSRNATGARRIRAGLPGDWKVADKTGTGDYGRANDIAVVHPPRTGPLVLAVMTDR +PGHDAEPSDALIAEATRRTV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758AB0D +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFSQ +PGADAAPRADVVTEAARIAA--- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=UPI0006803E4B +--KINEDLAAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLNDMD +NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSVGGP +RGVTMFLRTIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYEARI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITG +TDLSLQARDQVIAQISQLVLDEy +>[subseq from] Beta-lactamase n=1 Tax=Actinobacteria bacterium HGW-Actinobacteria-11 TaxID=2013646 RepID=A0A2N3GUI9_9ACTN +-------LQELEWRFDARIGVHAIDTGTGRSI-AHRDDERFAFCSTYKAIAAAEILRSRA +--ISGLEKRVRFTADDLVSYSPVTEQRVASGMSLRELCVAAVRFSDNTAGNLLFRELGGP +QGMASALREIGDDVTVMERIEPELNTAIPSETRDTSTPRMLVRDLQAYATTDLLPIEKRS +ILRGWMSGNATGDALIRAGLPDGWTVADKSGAGAYATRNDIGIVFPPGKSPIVIAVLTSK +LRQDATYDNEVIAEATRLVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A69DAD +-----NELTSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRRQ +SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGDP +KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSGGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP +EDPTSTKGKPTIAAAARIALRAf +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas niordiana TaxID=2508711 RepID=UPI0010A07D4A +--DLDQRLAELERATDDRVGVALMNVTTGAVA-SHRGDERFLFNSTGKFFIAAAVLARVD +EGSETLDRRIVVEKGDLVGWTPITEKRLGEPLTVAELCQAAVAWSDNAAANALIDSVGGP +KAVTAFLRAIGDDTTRLDRVEPDLNTDHEGDERDTTTPLAMMATLRTLLLGDALTPSSRH +QLAAWMIEGKVGDARLRAGMPSSWLVGEKTGTNGVGNASDIGIGWPGDRGAVIAVAYTKM +PGATGQQRDEAIATVGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium kansasii TaxID=1768 RepID=UPI000F013920 +--DVQSRFAELEHKYAARLGVYVPASGATAAI-AYRADERFAFCSTFKGLLVAAVLHQYP +--LSHLDKVVTYTSADIRSTSPITQQHIATGMSIGQLCDAAIRYSDGTAANLLLAEIGGT +TAFTGYLRSLGDSVSRLDQEEPELNRDPPGDERDTTTPNAIALDYQQLVLGDALPADKRA +MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPTGVPHVVAILSDR +AGYDAEPSEALVADAARCVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000981EF9D +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMTGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PQADAAARADVVTSAARIAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB94_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. ATCM1_4 TaxID=2259330 RepID=A0A4R4IGY7_9GAMM +-----DDFAALEALSGGRLGVCLWNPDSGVRI-GHRMEERFPMCSTFKFLLSAAVLHAAD +QGQLSLDRRVPVRAHDILSNSPGTERHVGKDMTVRDLCRTTMIVSDNAAANLLLPLVGEP +AGLTAFLRAQGDAVTVTARYEPEANRFAPDDPRDTTSPAAMAGNLQRFVLGDALGTAARQ +QLADWLIDNETGDARLRAGLPEGWRVGDKTGSNGRDTTNDIAVLWPAGGSPWILASYLQG +SALDDDGRNGILRRVGELA---- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCBA15_001 TaxID=1898731 RepID=A0A1S2GX72_9MICO +---TDRAFRALEAQHDARLGVVAIDTGSGHRV-QYRPGERFPFASTNKTFIAAAVLAASS +--DADLDTVVHYGRGDLLSYAPVTTRFVDSGMTVGELIDAAMRFSDNTAANLLVARVGGP +AAVEQWLRGTGDRVTNVDRTEPDLNQATPGDERDTTTPAQFAADVRSVLLGTTLEATDRT +FLRDTMLDNTTGAGTIRAGVDAAWPVADKTGTGEYGVRNDIGVVYPAGGAPIVVVVMTAT +DRADAQADDALVAAASGTAV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. ABCPW 11 TaxID=1637859 RepID=A0A103BEU2_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKATPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAVLWPPSRAPIVMAVSFTQ +PEAAAAARADVVAAAARIA---- +>[subseq from] Beta-lactamase n=1 Tax=Lentzea violacea TaxID=128104 RepID=A0A1G9TRR5_9PSEU +-----DALSELEKKFDARLGVYAMS-DNGSTI-EHRADERFAFCSTFKGLAAAAVLHRNP +--MSHLDTVVTYTEADLMKSSAITRQNVRTGMKLRDLCDAAVRYSDGTAGNLLLRDLGGP +AELTRYLRELGDTETRMDRVEPAITSATPGDPRDTATPRSLGTDYQRIVLGDALEPAKRD +FLTGLLERSVTGAKRVRAAVPAGSRVANKTGTGQYGTVNDIAVVWPPGREPVLIAIMSSK +STADAKYDEALVAEAAAYVVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000A06A233 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ +LQADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. WAC08241 TaxID=2487421 RepID=A0A429PAD5_9ACTN +---HRREFRALEEAFDARLGVYAIDTGTGREI-THRDGERFPYASTFKALAAGAVLRE-- +EGLGGMERVVRYTKDELVDPSPVTEKHVDTGMTLDALADAAVRYSDNTAGNLLFEELGGP +KGLQAVLRSIGDGVTRMDRIEPGLGDWRPGEVRDTSSPRALAGDLRAFVLGDVLRAPERK +RLTTWLRTSLTGDGTIRAGVPGTWVVGDKTGTATYGGRNDMAVVWPPDGAPIVMAILSTR +SDREAEPDDRLVARAASVVA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium senegalense TaxID=1796 RepID=A0A378T2U5_9MYCO +---IDDQLAELERRDNVLIGLYASNLDSGRTL-THRADQIFAMCSTFKGYAAARVLQLAE +RGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPSQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS +QAHDAENLRPLIGELTALV---- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A172WXH6_PSEST +--ALTETVASIEARTGGHIGVSVTALESGQSW-SHRGDERFPIASTFKAFSCGHLLALAD +RDEVELDTRVRFDETDLQSYSPITKDRVGGSMSLFELCSATTSMSDNTAANLILRNTGGP +QGFTTFMRSIGDAVTRLDRYEPELNDVGPGEERDTTTPMAAARSLETLLLGDSLSTHSRE +QLKAWLVNNKVGGPLLRASLPEGWKIADRTGAGGYGSRGIIAVIWPQGSEPVIVAVYLTG +TTLTLEERDATIAEVGAALV--- +>[subseq from] Beta-lactamase n=1 Tax=Neisseriales bacterium TaxID=2053582 RepID=A0A5C8B084_9NEIS +-----QQMSKLESTVGGRIGIAVYNTRNKETL-SYRGNERFPFCSTGKVMTVAAILKASE +KESDLLTKIIKYTKTDTDKYAPITSKYLAKGMTISELSQAALDYSDNTAMNLLVAEAGGV +GKITDYARLIGDEKFRLDRMEPELNTSIPADKRDTTTPLAMTMSLDKLVLGQSLESNSQI +YLTKWLKANTTGDKRIRAGLPQGWIVGDKTGTGAYGTTNDIGVIWAAKCDPIVISIYYTQ +DQKAAKSNDSVIASATKVAID-- +>[subseq from] Beta-lactamase (Fragment) n=7 Tax=Xanthomonadaceae TaxID=32033 RepID=D2CGR5_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000668AB8D +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMIGGARGATGIAAGAPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9140 TaxID=2184572 RepID=UPI000F568F7D +--AAQAELAALETASDGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVAAAAAILARGS +LDASLLPRRILYRRYDVVAGSPVTESHVDTGMTIAQLCAAMLQAGDKGAGNLVMGVLGGP +QAVTSFAHESGDSAFRLDRWEPELNQVAPGDVRDTSTPVAMVDLLQRLLLGDTLREPQRA +QLTEWMTGGARGAAGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAVRADVVASAARIATGAf +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. SAU14A_NAIMI4_8 TaxID=2072409 RepID=UPI000D53C5E7 +------DFAALEKASGGRLGVTVLDTGSGRRLgGHRQHERFPMCSTFKSMLVAHILSLAD +AGRLSLDTRVPITERDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP +AALTAFLRAQGDTVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGDGLLPPSRL +QFADWLVDNQTGDACLRAGLGPRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG +ASVDEAQRAAVLARVGAL----- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. Ru87 TaxID=2044307 RepID=A0A2B8B2X1_9ACTN +--EVTRRLRALEREHSARLGVYARNLATGATV-LHRTDERFPVCSLFKTLAAAAVLRDLD +RSGEFLAKVVHYTEDELDKWSPVTGENLEHGMTVDELCHAAITRSDNSAGNFLLRELGGP +GAITRFCRSIGDDRTRLDRWEPELNSAEPWQWKDTTSPGAIGRTYARLVVGDVLEPHDRE +RLTGWLLANTTSGEQFRKGLPADWTVADKTGAGGYGTTNNAGVAWTPDGAPVALAVLTTK +FHQDAGNDRALVAGTAELL---- +>[subseq from] Beta-lactamase CARB-3 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=BLC3_PSEAI +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKLLFGSALSEMNQK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGHSIFDVy +>[subseq from] Beta-lactamase class A n=1 Tax=Thermostaphylospora chromogena TaxID=35622 RepID=A0A1H0ZYX1_9ACTN +-nRVTKELRELEASFKGRIGAYAVDTATGKTI-GYRAGERFPLLSTFKTFLCAAALHKAR +TTPGLMEKRIRWTENDLVDHSPVTEKHLKNGLTVAELCKATITTSDNTAANLVLKEIGGP +AGLTRYFRSLKDPISRLDRYETELNNWSLHDRRDTTTPRAIGRDMRAVTVGKALHPKDRE +RLNAWLIANETGDHRIRAGLPKSWKIGDKTGTVPHGSGNDIAIIWPGKSAPIIMAIYTYR +KAEDAPVAEEVIAKTATILA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium vignae TaxID=1549949 RepID=A0A4Q0R9B1_9BRAD +------ELETYERESGGRVGLYAENLVNGKKL-AWRADERFVMCSTFKASLAACVLGRVD +RGEEQLAAMIPYGQADLLEYAPVARENLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP +AALTGFWRSLGDTTSRLDHDEPELNRSPPGNPQDTTTPAAMANNLRRLVLGEALSAQSRV +QLTEWMVNCKTGANRLRGGLPAGWKIGDKTGYNGKDAAGDIAVAWPKPDTPVLITAYVQG +GTPTPAKIAGVFAQIGRMVTD-- +>[subseq from] class A beta-lactamase n=2 Tax=Citrobacter koseri TaxID=545 RepID=UPI0009B9008E +---------QEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD +RKVLALSASTQFESSQLVEYSPITEKHVVPDMSWAQLCSAAVSYSDNTAANLIARKLNGP +QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE +QLMQWMRDDKVADSLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ +TPATMAQRDAAIVRIGESLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-24572 TaxID=1962156 RepID=UPI000A37832E +-----ARLRRLEREHTARLGVFARDMRTGRTV-AYRADERFPMASLFKTLAAAAVLRDLD +RDGEFLARRIHYTQAYVERLSLIAAENVAGGMTVAELCDATIRFSDNTAGNLLLKELGGP +TAVTRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLSYARLVLGDTLEPHDRA +RLTDWLLRNTTSTEKFRRGLPADWALADKTGSPRHGGANDVGVTWRPDGTPIVLSVLTTQ +PEEDAPTDNPLVAATAALLAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Comamonas sp. Tr-654 TaxID=2608341 RepID=UPI0014204DF5 +-kTLSDELAALEIQSQGRLGLHVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARVLYLSQ +RDEIRLWRKLYYSPAEVVAWSPISEKWAGANMTVQELCEAMVVVSDNTAANVMLEASGGP +AALTQWLRELGDGTTRLDRNEPSLNTALPGDERDTTTPQAMVHSLQKLLLGDVLEGYARA +LLQQWLADSRTGDKRVRAGMPSDWKVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG +SPLDGAGREAVLAKAGEAIK--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. 141 TaxID=1120797 RepID=UPI0003699358 +---LDDQIAGLEQRNNALIGIFAANVDSNRTV-AHRADETFAMCSTFKGYAVGRVLQQVD +RGQLALDTRIFIDPSAIVANSPVTEERAGADMTIGELCQAALQHSDNTAGNLLLKMIDGP +PGVTAFARSIGDDRTRLDRWETALNSAIPGDLRDTSTPAALGAGYRALLTADVLSRPQRQ +QLEDWMRGNET--SSLRAGLPAGWTSADKTGSGDYGSTNDVGVAYGPDGQRLLLAVMTRS +RADDPEAAN-------------- +>[subseq from] Beta-lactamase n=2 Tax=Comamonas testosteroni TaxID=285 RepID=A0A1Y1J6V8_COMTE +-kTLSDELAALEIEAQGRLGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ +RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVLVSDNTAANVLLEASGGP +AALTQWLRELGDGTTRLDRNEPSLNTALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA +LLQQWLVDSRTGDKRVRAGMPGDWKAGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG +SQLDGAGREAVLARAGEAIK--- +>[subseq from] Class A beta-lactamase n=5 Tax=Mycobacteroides TaxID=670516 RepID=A0A0R3EKR5_9MYCO +-----SELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYAQSDLMEWAPITSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEDQLN--VPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD +LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP +DDPKSTQGKPTIAAATRIALKAf +>[subseq from] Beta-lactamase n=2 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A249VY78_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQMDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNSAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILEHy +>[subseq from] Beta-lactamase n=1 Tax=Agromyces sp. NDB4Y10 TaxID=1775951 RepID=A0A164CTG2_9MICO +---ASDELSALEQEYGARVGVYAIDTGSGDVV-AYRGDERFAYASTIKALLAAAILQQVD +----DLDRVVPYSADVLGSHSPVTSGAVGGGLSVRDLAEAAVRVSDNTAANLLLDQLGGP +EGFAAVLAEAGDATTNPVRVETELNTAVPGDTRDTSTPRALVESLRGFALGGLLTDARSD +TLIEWMSGNATGDTLIRAGAPDAAIVADKSGTGGHGTRNDLGIVWPVDGEPIVIAVLTTR +GVPDAPSDDALVADAAAAVLSAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075C5072 +--AAQAQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLIGSANSIAGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADASPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Herbidospora mongoliensis TaxID=688067 RepID=UPI0008344D6F +----VADLRALETSYHGRIGVYAIDTATGRTI-AYRSGERFPLASTFKGVLAAAVLDKKP +---DILGKRILIKKKDLLPNSPETEKHVGSRMTVAALARAAVTKSDNAAANLLLKQVGGP +KGLTRYFRGLNDHVSRLDRTEPGLNDWTPKDPRDTTTPAAIARDLKALTVGTALDAGDRR +IFTGWLVANETGDKRIRAGLPKSWRIGDKTGTGSYGSANDYAIIWPKGSKPIIMAIYTNR +TAKNGTADETVIAKAATIAA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI000634A596 +-sQLNEDISLIEQQTSSRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRLEPRLNEATPGDNRDTTTPNSMVNTLRTLIEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLIAQISQLILQKy +>[subseq from] class A beta-lactamase n=1 Tax=Geodermatophilus saharensis TaxID=1137994 RepID=UPI000B77840F +--AVAARLAALEEEYGARLGVHAVDTGSGRTI-AHRADERFAYASTVKALAAGALLARTS +--PVDLQRGVPISRADLAPHSPVTEAAVGGSLTLEQLCDAAVRFSDNTALNLLLRELGGP +AGLDAALERVGDDVTEVSRTEPALNTAVPGDPRDTTTPRALATTLRAYAVGAGVAVEDRL +LLADWLRRNTTGDTLVRAGVPGDWEVGDKTGTGAYGTRNDVAVLTPPGRAPIVLAVMSSR +GERDAGHDDALIAAAAGVVAD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudomonas abyssi TaxID=170540 RepID=A0A2A3MFJ5_9PSED +--ALNLALAELERASQGRLGVSLLDRGSGQVA-SYRGDERFLMLSSFKTLAAAYVLARSD +QGIDQLSRRISITEEDMLEYAPVTRRHIGPRMTLAELCHATITTSDNTAANLILRSYGGP +QALTQFIRSLGDTITRHDRYEPELNQSHSVEPMDTTSPNAMSNTLNTLLLGSALKPESRQ +LLQSWLMANTTGDRRLRAGVPPSWIVGEKTGTAGL-GANDVGFIQAPSGSPVIVSVYLET +DTIAAPERDQIIAAVGKRAA--- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI000DE296C1 +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTMACAKLLYDAE +HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] Beta-lactamase n=4 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A2A3I9A5_9ACTN +---LAAQLRDLEQQYSARLGVFARDTATGRTV-KYRADERFPMCSVFKTLAAAAVLRDRD +--DDFLGHRIRYAEKYVTDYAPITGKNLANGMTVGELCAAAVSYSDNGAGNLLLGELGGP +AAVTGFCRSIGDGTTRLDRWEPDLNSAEPWRKTDITSPRAIGQTYARLVLGSTLTTADRT +RLTRWLVANTTNGERFRAGLPADWTLADKTGGGQYGVANDVGIVWPPGRPPLVLSVLSTK +FDPEGPTDNPLVAKAAALVA--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas sp. NML130969 TaxID=2480811 RepID=A0A4Q8M3X8_9GAMM +-----RDFAALEQVSGGRLGVTLLEVGTGRRM-GRRQDERFPMCSTFKALLAAHVLSLAD +AGALSLDERLPIRQAQLLSWAPESERHVGKDLTVRDLCRAAVTNSDNTAANLLLARAGGP +PALTAFLRKQGDAVTRSDRYEPEMNNFAPDDARDTTSPAAVAASLARFAVGDGLSKASRA +QYADWLIDNQTGDDCLRAGLGKRWRVGDKTGNNGRDTRNDLAVLWPLGGTPWVLVALLQG +ARVDADQRDAVLARVGALA---- +>[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides abscessus subsp. bolletii 50594 TaxID=1303024 RepID=R4UF27_9MYCO +-----NELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL +SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDSAPIVMAVLTVP +EDPTFTKGKPTIAAAARIVLRAf +>[subseq from] Carbapenem-hydrolyzing beta-lactamase FRI-4 n=1 Tax=Enterobacter asburiae TaxID=61645 RepID=A0A1S7IV31_ENTAS +-----EQMRELETSFGGRIGVYILNTKNGKEF-SYRQDERFPLCSSFKAFLAASVLKRTQ +DKSVSLDDMMEYSGRVMEKHSPVSEKYRETGASVQTLAKAAIQYSDNGASNLLMERIGGP +EGLTAFMRSTGDTDFRLDRWELELNSAIPGDERDTSTPKAVAISLNNIAFGSVLDAKNKS +LLQDWLKGNTTGNARIRAAVPDKWVVGDKTGTCGYGTANDIAILWPDANSPAVMAVYTTR +PNQNDKHDETVIKNAAKIAIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007520D9E +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAVPRADVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F57B555 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMAGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PQADAAARADVVTSAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. C1-2 TaxID=2720022 RepID=UPI00143275DA +---LARRFRALEKEYAARLGVYAHDTATGRTV-RYRADETFPLCSVFKALAAGAVLRDLD +RDGEFLAKRVHYTQKQADDYAPVTGENVAGGLTVGELCAAAVSESDNCAGNLLLSELGGP +SGITRFCRSLGDDTTRLDRWEPDLNSAEPWRKTDLTTPQAIGRTYGRLLLGRALPEADRE +RLTGWLVANTTNTERFRAGLPKDWILADKTGGGSYGVANDVGVVWPPARPPLVLAILSTK +LDPAGPTENPLVAKAAAAVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces jietaisiensis TaxID=235987 RepID=A0A1G7DB66_9ACTN +---LARRFRALEKEYAARLGVYAHDTATGRTV-RYRADETFPLCSVFKALAAGAVLRDLD +RDGEFLAKRVHYTQKQADDYAPVTGENVAGGLTVGELCAAAVSESDNCAGNLLLSELGGP +SGITRFCRSLGDDTTRLDRWEPDLNSAEPWRKTDLTTPQAIGRTYGRLLLGRALPEADRE +RLTGWLVANTTNTERFRAGLPKDWILADKTGGGSYGVANDVGVVWPPARPPLVLAILSTK +LDPAGPTENPLVAKAAAAVAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinopolymorpha cephalotaxi TaxID=504797 RepID=A0A1I2ZC81_9ACTN +--DLTRELRALEKRYDTRLGVYARNVGTGQAV-RYRGDERFPMCSTFKGLLAAHMMRDYD +RRGEFLERVLHYTRDDLAGWSPITENNLETGMAVRDLCLAATAFSDNGAANVLLRATDGP +PGFTRFCRAIGDEYTRLDRYETDMSEAKPGDDRDTTTPEAMGRSYARLVLGRVLKPFHRD +QLVSWLKVNTTSGPRFRAGLPDDWVLADKTGNGGYGTVNDIGIVWTPKGTTLLLSVLSTK +EMKGVEADPRVLADTARLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI000D8C5185 +--ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD +AGKLALNDTVKVRSEDLVEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLAKIGGP +AALTAYLQSIGDNVTRLDRNEPTLNEAVKNDPRDTTTPNAINHTLNTLVLGETLSSASRQ +QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSTQQEPMFVSIYLTQ +TEASFDERNAAIVTIGKSIFDTf +>[subseq from] Beta-lactamase n=2 Tax=Comamonas TaxID=283 RepID=A0A0M2DLK3_9BURK +--TLSDELAALEIQAQGRFGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ +RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVLVSDNTAANVLLEASGGP +AALTQWLRELGDGTTRLDRNEPSLNTALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA +LLQQWLVDSRTGDKRVRAGMPGDWTVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG +SSLDGTGREAVLARAGEAIK--- +>[subseq from] class A beta-lactamase n=1 Tax=Herbidospora yilanensis TaxID=354426 RepID=UPI0007862FDC +----VAELRALETSFKGRIGVYALDTATGRTV-AYRSGERFPLASTFKGVLAAAVLDKKP +---DILGKRILVRKKDLLPNSPETRKHVGSRMTVAELAKAAVTKSDNAAANLLLRQVGGP +KGLTRYFRSLDDHVSRLDRDEPGLNRWHPGELRDTTTPAAIAADLKVLTVGGALDAGDRR +TFTGWLVANETGDDRIRAGLPKSWRIGDKTGTGGYGTANDYAIIWPKGSKPIIMAIYTNR +TDRNAAADESVIAKTATIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. NFR13 TaxID=1566285 RepID=A0A1I4M8N4_9BRAD +--ALHAPLQAYERDTGGRIGVYAENLKTGTKI-AWRAHERFVMCSTFKASLAACVLARID +RGEDKPDQMIPYAAADLLQYAPVARDNLARGLSVADMCKATVELSDNTCANMLLARVGGP +AALTAFWNKTGDSVSRLDHNEPLLNRSRPGNPQDTTTPAAMAGNVKRFITGNVLTPASRD +QLIDWMVNCKTGDKRLRAGLPKTWKIGDKTGNNGKDAAGDIAVTWPKPDQPVVIAAYTQG +GTPTAPQLETVFTAIGEMV---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID9124 TaxID=2706108 RepID=UPI0013E002DB +---ATARLRELERTHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD +RDGEVLGKVIHYTKADCVSDSPVTDTHLASGLSVARLCDAAIGDSDNTAANLLLRELGGP +AAVTRFARSLGDRVTRLDRWEPLLNSAEPGRVTDTTTPSALARDYARLVLGNVLERRDRE +RLTYWLLNCRTSGTRFRAGLPPEWAVADKTGGGSYGSCNDVGVAWTPEGVPVVLAVLTTK +PASDAAGDHPLVRDAAEALA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. AU31280 TaxID=2015353 RepID=UPI000B7AC80C +--TAHAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAMLWPPSRAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI000758BECD +--AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHESGDTVFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPERA +QLTEWMTGGARSATGIAAGVPPGWRIADKIGSGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIAT--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces europaeiscabiei TaxID=146819 RepID=UPI0006284352 +---LSRQLGELEREHAARLGVFAHDTATGRTL-AYRADERFPICSVFKTLGAGAVLRDLD +RDGEYLAKRIHYTKEYVEAYCPITARNVAAGMTVGELCSASVSHSDNGAANLLLRELGGP +TAITRFCRSLGDRTTRLDRWEPQLNSAEPWRKTDTTTPRAIGGTYARLLLGRALPDADRE +LLTDWLIANTTNVERFRAGLPADWTLADKTGGGSYGVANDVGVVWPPLRPPLVLSVLTTK +HAPEGPSDNPLVAKAAGLVAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium asiaticum TaxID=1790 RepID=A0A1A3NZE4_MYCAS +--DLSHQFDQLERRYEGRLGVYVPE----PAI-AYRADERFAFCSTFKAPLAAAVLHQYP +--LDHLDKLVSYNRSDINSVSPVTEQHVDTGMTVGQLCDAAVRYSDGTAANLLLAEVGGP +AGFTAYLRTLGDNVSRLDQPEPQLNRDAPDDPRDTTTPHAIALVFQQLLLGDALPADERV +LLVDWMTRNTTGGKRIRAAFPPDWKVADKTGSGDYGRTNDVAVVWSPSGAPHVIAIYSDF +VGYDAQPNDAFVADAARIVAS-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. BE17 TaxID=2656644 RepID=UPI00128D295F +--AAQAELAALEKASNGRLGIAALDTSNGVRI-AHHARERFPLCGTYAVVAAGAILARGS +LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIAQLCEAMLRSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTTFRLDRWEPELNKAAPDDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Jiangella sp. KE2-3 TaxID=1623398 RepID=UPI000E357074 +------AVRELERTHDVVLGVSATNLATGAQL-AHRAGDRFPILSVFKSVVAAAVLRDLD +--DARLDHRVWYPPADILLNSAITAEHVDTGMTVAELCDAAIRYSDNAAGNLLLREVGGP +RGLTAFARSLGDRATRLDRWEIELNSAEPGDVRDTSTPAALARTFAGLLVGDLLRPADRR +RLRNWMLANTTSGPRFRDALPDGWLLADKTGAGDYGTNNDAGVAWNPAGEPIVIVAMSRR +TERDAERVDAALADVARLVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Root264 TaxID=1736503 RepID=A0A0Q9ACN2_9ACTN +--ALSRRLRDLERRYSARLGVFALDTATGRTA-EYRADERFPLCSVFKTLAAAAVLRDLD +HDGAYLARRIHYTEKDVTDYAPVTGENIAGGLTVEELCAAAVSESDNGAANLVLRELGGP +TAITRFCRSLGDRTTRLDRYEPALNSAEPWRRTDTTRPRAIGLTYARLVLGRALESADRR +RLTGWLIANTTNTERFRAGLPDDWTLADKTGGGQYGVANDVGVVWPPGRPALVLAVLSTK +HDPAGPTDNPLVAKAAALTA--- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf87 TaxID=1736243 RepID=UPI000700F869 +---ATNTLREIERRVGGRLGVSVGKSNAPPLL-GHRADERFPMCSTFKVPAAAALMARVD +AGTESLDRALPYGEEDLLKYAPVTRKALEAAISVADACAAAVEWSDNTAANLMLNVLGGP +LALTGWLRGIGDPTTRLDRTEPDLNTAIPDDPRDTTTPDAMRTTLEQILVGTALSRATRT +RLDGWLAAGRTGSKRLRAGIPPDWKVGDKTGSGDNGTYNDVAILRPPWQAPILAAVYLTG +STAPITDVDAAYAEIGRMIAE-- +>[subseq from] carbapenem-hydrolyzing class A beta-lactamase FRI-9 n=1 Tax=Enterobacter asburiae TaxID=61645 RepID=UPI0010CA2EDA +-----EQMKELENSFGGRIGVYILNTKNGKEF-SYRQDERFPLCSSFKAFLAASVLKRTQ +DKSVSLDDMMEYSGRVMEKHSPVSEKYRETGASVQTLAKAAIQYSDNGASNLLMERIGGP +EGLTAFMRSTGDTDFRLDRWELELNSAIPGDERDTSTPKTVAMSLNNIAFGSVLDAKNKS +LLQDWLKGNTTGNARIRAAVPDKWVVGDKTGTCGYGTANDIAILWPDANSPAVMAVYTTR +PNQNDKHDETVIKNAAKIAIN-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. ACS4331 TaxID=1834121 RepID=A0A1A1X9C1_9MYCO +----DAALAALEQRYDALVGLFALDLDSGRSL-AFRDDDPFAMCSTFKTYAAGSVLQRDQ +RGELQLDRQVFVDPAELVANSPVTEVNAGSSMTLAALCQAALQRSDNTAANLLLQTIGGP +PAITAFARSIGDDRSRLDRWETELNSALPGDPRDTSSPRALAGGYRALLTGTVLDEPHRA +QLETWMRGNATSEKSLRAGLPPGWTSADKTGAGDYGSTNAVGIAFAPDGRRLLLSVMTRS +RSPDAPWLQPLIAEVTALAVT-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. F12 TaxID=2070776 RepID=A0A4U1X2L0_9VIBR +-----QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDHE +NEGLDLESKVGVNSDELIAWSPVTKAFVGKEISLRGACAATMAMSDNTAANIVLASIGGP +NGLTEFLRSTGDRKTRLDHIEPDLNHARPGDERDTTTPNTMVKTLNKLLYGSALSEESKA +QLKTWMIDNKVSDGMIRSILPDGWKVADRSGAGAYGSRAITAIVWSENRAPLIISISLTE +TELTIPERDTVINEIGELIFDEy +>[subseq from] Beta-lactamase n=1 Tax=Labedella endophytica TaxID=1523160 RepID=A0A3S0WZC7_9MICO +--ATDAAFSALESEFDARLGVYALDTGTGEEV-VWRADERFAFASTYKALAAGAVLDQVG +--IEGLDTSVMYGGKALVEYSPITEKYADIGMTIGDLADAALRYSDNTAGNMLFEVLGGP +TGFDTALEALGDDVTESVREETELNAAERDETLDTSTPTALATDLRAYLLGDVLSDDERA +VLTDWMVRNTTGDTLVRAGVPDDWTVADKSGSAKYGTRNDIAVVWPTDGDPIVLAILSDR +DTEDAERDDALIARATEEAV--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A377ZRY4_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGER-V----------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. BTF04 TaxID=2708300 RepID=UPI0013D3EFD2 +-eAARRRVAAIEHELGGRIGVAVLD-GSGPVL-LHGADDPFPLCSTFKLLATAAILKRVD +DGTLRLDQEIAYDAADLTAYAPITAAALRDGMSLESLCAAAMVWSDNTAANLMLRTLGGP +AALTAYLRGLGDPTTRLDRTEPTLNTAIPGDPRDTTTPAAMAKTTRILLTGAALRADSRN +RLESWMVAARTGTKRLRAGLPPDWIVGDKTGSGDNGTANVVAILRPPARPPLVAAIYMTG +STQPPETRDAAHAEIGRILA--- +>[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. SCN 70-31 TaxID=1660129 RepID=A0A1E4GVL5_9CAUL +-----PAWASLEARVGGRLGVFGVNSGNGRTF-GWRADERFPMCSTFKGLLAGAVLARVD +ARRERLDREVQLSPADMVAHAPVTSRYLAAGVRVETLCQAIVEVSDNPGANLLLKTLGGP +RGFTRHIRAQGDRATRLDRYETELNSAIPGDPRDTTTPAAMVGSYRRLLLGPALTLASRR +RLAGWMEAASTGLTRLRADLPAGWRAGDKTGSGAHHTANDVAILWPPAGAPILVGCFSTQ +ATAP-EARDAVMAGIGRLAAE-- +>[subseq from] Beta-lactamase PSE-4 n=3 Tax=Pseudomonas aeruginosa TaxID=287 RepID=BLP4_PSEAI +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMEERNDAIVKIGHSIFDVy +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium kubicae TaxID=120959 RepID=UPI00080012E9 +----SDRIDELESQYHAFAGVYAQDLDSGHTV-THRADDPFAMCSTFKAYAAGRVLQKAQ +RGELDLDQATFIDPNELQPNSPVTAPHAGHSMPLAQLCAAALQRSDNTAANVLLQAIGGP +PAITEFARSIGDDRTRLDRWEVELNTAIPHDPRDTSTPRALGAGIQNLLAGTVLAPPQRR +QLETWMRGNVT--STMRAGLPPGWTTADKTGSGDYGSTNDVGIAYGPNGQRVLLAIMTRS +QAPDADALQPLIADVTRAVL--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A431I7S4_9PROT +hdDLMAQLRSLESTSATHIGVYAMNSANNQKL-EFNAEKRFPFCSTAKFITVAAILKNSE +SNPDYLQQQIKFTHYDVQTYSPITANHVTNGMTIAELSFAALAYSDNTAMNLLIASLGGI +TQVNNYARTLNDSRFRLDRPEPRLNTAIPHDLRDTTTPQAMGQDIQQLLLGNALNATSRD +KLAKWMIANTTGAKRIRAGVPQGWAVAEKTGSGDYGTANDIGVIYPNKCKPLVMSIYTTS +DKKEAKYQDEVVAKVTKLVLQ-- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase FRI-3 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A1S6GNZ2_ENTCL +-----EQMRELEAAFGGRIGVYILNTKNGKEF-SYRQDERFPLCSSFKAFLAASVLKKTQ +DKSVSLDDMMEYSGRVMEKHSPVSEKYRKTGASVRTLAKAAIQYSDNGASNLLMERIGGP +EGLTAFMRSTGDTDFRLDRWELELNSAIPGDERDTSTPKAVAMSLKNIAFGSVLDAKNKS +LLQEWLKGNTTGNARIRAAVPDKWDVGDKTGTCGYGTANDVAILWPDANSPAVMAVYTTR +PNQNDKHDEAVIKNSAKIAIN-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis salina TaxID=245836 RepID=UPI0003458942 +--AAEEAFTDLESEYDARLGVYALDTGTGQEI-GYGADDRFAYASTFKALAVGALLHQHG +--AGVLDEEVPLGEDDLLTHAPVAEQLVEEGMTLREASDATVRHSDNTAGNLVLERLGGP +DGFEEALREIGDDTTSADRWEEELNEAAPGDERDTTTPRALAESLQTYVLEDTLAEDERE +FLTDLLVRNTTGDTLVRAGVPEDWEVGDKTGGGGYATRNDIAVAWPPEGDPVVIAVMSDR +EDEDAEYDDALVADATETVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Ag82_G6-1 TaxID=1938853 RepID=UPI000BE479C6 +------RLADLEREYGARVGVYALATGTGATV-VHRAGERFAFCSTFKALAAAAVLHHRS +--AGGLDRRVTYTEADLRSTAPVTGKHVATGMTLRELCDAAVRFSDGTAGNLLMRDIGGP +AGLTAYLRGLGDTTSRMDHYEPELHDVPPDDPADTTTPQAIATDFRDLLLGTALPVRERR +LLMGWLSRNATGARRIRAGLPGDWKVADKTGTGDYGRANDIAVVHPPRTGPLVLAVMTDR +PGRDAEPSDALIAEATRRTV--- +>[subseq from] Beta-lactamase n=1 Tax=Geodermatophilus saharensis TaxID=1137994 RepID=A0A239C0A2_9ACTN +--AVAARLAALEEEYGARLGVHAVDTGSGRTI-AHRADERFAYASTVKALAAGALLARTS +--PVDLQRGVPISRADLAPHSPVTEAAVGGSLTLEQLCDAAVRFSDNTALNLLLRELGGP +AGLDAALERVGDDVTEVSRTEPALNTAVPGDPRDTTTPRALATTLRAYAVGAGVAVEDRL +LLADWLRRNTTGDTLVRAGVPGDWEVGDKTGTGAYGTRNDVAVLTPPGRAPIVLAVMSSR +GERDAGHDDALIAAAAGVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI0007ED4B82 +---IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYAAARVLQMAE +HGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS +QAHDAENLRPLIGELTALV---- +>[subseq from] Carbapenem-hydrolyzing class A beta-lactamase FRI-8 n=1 Tax=Enterobacter sp. 18A13 TaxID=2565914 RepID=A0A4P2WTJ5_9ENTR +-----AQIKELETVFGGRIGVYLLNTENGKEF-SYRQNERFPLCSSFKVFLAASVLKKTQ +DKSFSLNDTVEYSGRVMEKHSPVSEKYLETGASVQTLAMAAIQYSDNGASNLLMERVGGP +EGLTAFMRSTGDTEFRLDRWELELNSAIPGDKRDTSTPKAVAMSLKNIAFGSVLDAKNKA +LLQDWLQGNTTGNARVRAAVPDKWVVGDKTGTCGYGTANDVAILWPDSNSPAVIAVYTTR +TNQNDKHDETIIKNAAKIAIN-- +>[subseq from] Beta-lactamase n=1 Tax=Roseivivax isoporae LMG 25204 TaxID=1449351 RepID=X7FDK5_9RHOB +---LALTVRQIEDRLDARVGVVVRDSATGWSW-GHRADERFLMNSTFKAPLCGALLARVD +AGETTLDTALPVTAADMVDHAPVTETRIGATMTLDALCRAAVDMSDNPAANIVLDHVGGP +EGFTSFLRGIGDGTTRLDRTEPGLNTYAAGDPRDTTTPAAMVATLERLLLGDALSAAARA +RLTGWMTPGSVTGALLRAHTPEGWHVADKSGAGRV-TRNIVGMVTPPGAAPHLVAIYLSE +AEVDFATRNAALSELSAAVV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Comamonas serinivorans TaxID=1082851 RepID=A0A1Y0EPD6_9BURK +---LAADLQALERQANGRLGVQVVDTGTGREA-GYRADERFMMLSSHKLLAAGLVLYRHD +QRQDSLARRIRFTRADLVSHSPVTERHVGGQMTLAELCHATLTTSDNTAANLIHDSYGGP +QGLTRFLRGLGDDITRLDRRETALNVPQAGEPLDSTSPRAITRSMGKLVLGYVLTPASRR +QLQDWLVANTTGGRRLRAGLPTGWRVGDKTGTAEV-GANDIGVAWPPGRAPLLLSVYLEA +PP--TAARDEAIATAARLAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=A0A0G3WYC3_BURPY +--AAQAELAALEKASNGRLGIAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIAQLCEAMLQSGDKGAGNLLMSVLGGP +QAVTSFAHGSGDTTFRLDRWEPELNQAAPGDERDTSTPVAMVDALQRLLLGDTLHEPQRT +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Phaeobacter porticola TaxID=1844006 RepID=A0A1L3I2V4_9RHOB +--DVTSVVHAWEAKLDARLGVLLRHPDTGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD +QGTDQLSAPVKIRAGDLVAHSPVTERYIGGTRTVAQLCDAAITRSDNTAANLLMERVGGP +AGVTAYLRQTGDSVTRLDRWEAELNSATPGDLRDTTTPRAVLTSLQSALFGSTLTAQSAG +LLADWMERNHLADALIRAHLPRGWRIGDKTGGGGHGSRAIIAHLQDPKGETYLAAIYITE +TTAKFAQRNQAISDIGRAMI--- +>[subseq from] Beta-lactamase n=2 Tax=Comamonas TaxID=283 RepID=A0A076PSC6_COMTE +--TLSDELAALEIQSQGRFGLYVVDTVSGAEA-GWRGDERFPMCSTFKTLLAARVLYLAQ +RSEIRLWRKLYYSPAEVVAWSPISEKRAGANMTVQELCEAMVVVSDNTAANVMLEASGGP +AALTQWLREMGDGTTRLDRNEPSLNTALPGDERDTTTPRAMVQSLQKLLLGDVLEGYARA +LLQQWLADSRTGDKRVRSGMPGDWKVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG +SPLDGAGREAVLARAGEAIK--- +>[subseq from] class A beta-lactamase n=1 Tax=Saccharomonospora paurometabolica TaxID=208085 RepID=UPI00022E7C0F +-----PDFAELERRYSARLGVYALDTGSGTEI-THRAGERWAFCSTIKPFTAMAVLQRTT +--LDGLDERITYSREDLVSYSPVTEQHVDTGMTLRAVLEAAVRKSDNTAQNLLLDELGGP +AGLQRALRELGDTVSHADRYEPELNDTAPDDIRDTSTPRALATNLRKLVLGDVLPPGKRT +ILREAMRNPPLTADLIQAGVPDDWQVEDKSGAGGYATRNDIAVLYPPERAPIVLVVLSDR +ARPDAEYDDALLAEAARVTV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID8455 TaxID=2706104 RepID=A0A6B3I9L6_9ACTN +---AVRRLAGLERASGARLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD +RDGEFLSRRIFYTAKDVERGAPETGKNLANGMTVEELCEVSITASDNCAANLVLRELGGP +TAVTRFARSLGNRVTRLDRWEPELNSAEPGRVTDTTSPRAITGTYGRLVLGDALNPRDRR +LLTGWLLANTTSGGRFRAGLPKEWTLGDKTGAGRHGTNNDAGVTWPPGRSPIVLTVLTTQ +PEEDAVRDDGLVADAARVLAE-- +>[subseq from] Beta-lactamase n=5 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LFA2_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. 5-2 TaxID=1926885 RepID=A0A2P4UPW6_9ACTN +---VTGRIDALERSYAGRIGAFAVDTGNGRTV-AHRADERFAFASTFKAALAAAVLHKAR +SDPGLLHRRLHWTADDLLPNSPVTEKHITDGLTAAELCRAAITRSDNTAANVLLKQVGGP +AGVTRYLRSLGDSVSRLDHNEPALNQWKPGQRQDTVTPAAIGRDLASVTVGRALAAPDRA +QLNVWLRATVTGDARIRASVPGNWLVGDKTGTGSYGTANDIAVVTPPGHAPLIIAIYTNR +NDPKGDADESVIARTTTLLI--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ag82_G6-1 TaxID=1938853 RepID=A0A286CK13_9ACTN +------RLADLEREYGARVGVYALATGTGATV-VHRAGERFAFCSTFKALAAAAVLHHRS +--AGGLDRRVTYTEADLRSTAPVTGKHVATGMTLRELCDAAVRFSDGTAGNLLMRDIGGP +AGLTAYLRGLGDTTSRMDHYEPELHDVPPDDPADTTTPQAIATDFRDLLLGTALPVRERR +LLMGWLSRNATGARRIRAGLPGDWKVADKTGTGDYGRANDIAVVHPPRTGPLVLAVMTDR +PGRDAEPSDALIAEATRRTV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces mobaraensis TaxID=35621 RepID=UPI0003466F80 +---VAERLRALEEAYHGRIGLAAFDTGSGRSV-TYRAHERFALCSTFKFLAAAAILDKAR +RDPGLLDRPVRYS--EVIDGSPVTKDNLSRGMTVRELCDATIAVSDNTAGNLLLEQLGGP +RAIGAFARTLGDRRTRLDRTEPTLNTNLPGDPRDTTTPAAMARDVYALTVGTALAAPDRE +QLNRWLEGCRTGDARIRKAMPAGWLVGDKTGTGERGAANDIAVVRPPGRAPLVVAVYTTR +VGGTETGDSEIIARAAGM----- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=A0A108ERE2_9BURK +--AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNVLMGVLGGP +QAVTGFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA +QLTEWMTGGARNASGIAAGVPPGWRIADKTGIGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIATGAf +>[subseq from] L2 family class A beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6B8IWP0_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas pavanii TaxID=487698 RepID=UPI0013E08173 +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=4 Tax=Bacteria TaxID=2 RepID=A0A4S0VGZ2_9RHIZ +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces mobaraensis NBRC 13819 = DSM 40847 TaxID=1223523 RepID=M3BGD5_STRMB +----AERLRALEEAYHGRIGLAAFDTGSGRSV-TYRAHERFALCSTFKFLAAAAILDKAR +RDPGLLDRPVRYS--EVIDGSPVTKDNLSRGMTVRELCDATIAVSDNTAGNLLLEQLGGP +RAIGAFARTLGDRRTRLDRTEPTLNTNLPGDPRDTTTPAAMARDVYALTVGTALAAPDRE +QLNRWLEGCRTGDARIRKAMPAGWLVGDKTGTGERGAANDIAVVRPPGRAPLVVAVYTTR +VGGTETGDSEIIARAAGM----- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Sulfitobacter TaxID=196795 RepID=UPI00055ADDED +--TLTNTVAQIEERLGARVGVSLLETGSELSW-AHREDERFMMNSTVKAPICGAVLARVD +ADEMSLTDTLNVQKDDILSYAPVTEKQVGTAMSLADLCLAAIDLSDNTAANMLLDHIGGP +QAVTEFFRQTGDEVSRLDRREPELNEFVPGDPRDTTTPAAMTKMLRGLLLGNVLSPSSRE +QLVEWMSIGGVTSNLLRADASKDWLILDKSGSGSH-TRNIIAVVVPEGGAPWVVSIFISD +VDADFETRNTALQQIGGAVM--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces subrutilus TaxID=36818 RepID=A0A1E5Q147_9ACTN +---AARRLRELEREHSARLGVFARDTATGRTV-AYRADERFPMCSVFKGLAAAAVLRDLD +EDGEFLARRIRYTREYVEKYGPETGKNLADGMTVEALCAAAVSLSDNAAANLLLEALGGP +AAITRFSRSLGDRTTRLDRWEPELNSAEPGRITDTTSPRAIGGTYARLLLGDALPSGDRG +RLTGWLVANTTNTGRFKAGLPADWILADKTGGGNYGVANDVGVVWPPGRAPIVMAVLTTK +PGAPAPRDEELVAKTARLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI000A101A5C +----DSEFAALEEQFDARLGVYAVDTGTGREI-EWRGDERFAYASTIKALAGAALLDDVG +--TAGLAKTVEISASDIIKHSPVTETRVGQSMTLDEICEAALTQSDNAAANFIFAELGGP +QAFDAQLDELGDAGTTVSRIEPDLNEALPGDFRDTTTPRASANNLREYVFGDALDDEEKT +ALTDWMKASQTGDTLVRAQLPEDWTVGDKSGGGMYGSRGDLAVVWPTDGRPIVISVLSSR +DEQEADYDDRLIAGAAAAAVDQ- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium peregrinum TaxID=43304 RepID=A0A4Z0HET2_MYCPR +---VDDQIAELERRDNALIGLSATNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMVG +RKQIALDNRVFVDPEAIVPNSPITETHAGSEMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAIGYHQILAGDALSPPQRR +QLDDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPNGQRLLLAVMTRS +QADDPKADNPLIGELT------- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. Amel2xC10 TaxID=1305826 RepID=A0A1X7C7I7_9ACTN +--HLARRFHALERRYAARLGVHAHDTATGRTL-AYRADERFPLCSVFKTLAAAAVLRDLD +RDGEYLARRIRYTKEYVTAYAPITDENVAAGMTVAQLCAATVSHSDNGAGNLLLRELGGP +TAITRFARSLGDPTTRLDRWEPELNTAEPWRRTDITSPRAIGGTYARLLLGGVLPRGDRD +LLTGWLVANTTNTARFRAGLPADWTLADKTGGGAYGVANDVGVVWPPGRPPIVLSVLSVK +HAPEGPTDNPLVAGAAALVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis kunsanensis TaxID=141693 RepID=UPI0003715CCF +---AEEAFTGLEEDYDARLGVYALDTGTGQEV-EYGADDRFAYASTFKALAVGALLDQHG +--AEVLDERMDLSEEDLLTHAPIAEEFLDQEMTLREASDAAVRYSDNTAANLVLERLGGP +EGYQEALREIGDDTTSADRWEEELNEAAPGDERDTSTPRAMAENLRTYVLEEPLAEDERE +FLTDLLVRNTTGDALIRAGVPEDWEVGDKTGGGGYATRNDIAVAWPPESDPVVIAVMSSR +GEQDAEYDDALVAEATETAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Lentzea aerocolonigenes TaxID=68170 RepID=UPI0004C356FC +------ALFELEKKFDARLGVYALS-NSGRTI-EHRADERFAFCSTFKGLAAAAILHRNP +--MTHLDTVVTYTEADLMKSSAITKQHVQTGMKLRDLCDAAVCYSDGTAGNLLLRDVGGP +AELTRYLRELGDTETRMDRVEPAITEATPGDPRDTATPRSLGTDYQRLVLGDALPQDKRD +FLTDLLERSVTGAKRVRAGVPQGSRVASKTGTGDYGTLNDIAVVWPPGREPILVALMSSR +SAADAKYDEALLAEAAAYVVK-- +>[subseq from] Uncharacterized protein n=2 Tax=Cellulomonas cellasea TaxID=43670 RepID=A0A0A0B9L0_9CELL +----QAAIAAIETESGLTLGVAAIDTGTGAVV-GHRADERVLLCSTAKVLVVAAALALRT +ERPGLLGEPVPIPAGQVVDHSPVTAEHEGGELPVAVLCDAAITQSDNTAANALMGLVGGP +AGVTAYVRTLGDEVTRLDRTEPELNQGAPGDERDTSTPAQVAADLRLLAVEEGLPPESRD +PLVGWMRGSTTGADRIRAGVPAGWTVGDKTGTGPNGEVHDVGVVWPPDGAPVVLAVYTSP +AAGSTEASAAVIARVAALVCEAf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE28D41 +---IVASAKRVEQKLDMRVGFTVIDTGDGTVT-GYRQDERFAMASTFKALACAAALSRGE +---AVLAKKTTIRQADLRPHSPVTEKRVGTSISTRALCEMTLRTSDNAAANAILKALGGP +AEVTGFLRQIGDETTRLDRYEPELNEARPGDPRDTTTPQAMAETLRRLLLQDVLDPQARD +RLEEWMAANAVADGLLRSRLPEGWQIADRSGAGGHGTRGVIALVRPPQGAPLVIAIYMDG +TKHPLKVRDAAIAEIGAAIFESy +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis listeri TaxID=53440 RepID=UPI00082DB117 +--DVSAEFEALEEEFDARLGVYAVDTGSGDTV-AFQEEDRFAFASTFKALLAGVVLSENS +--LSEMERVVTFDEGVLVPHSPVVEENLDSGMSLLELCDAAVRYSDNAAANLLLDEIGGP +AGFTEALGSTGDEVTNLTRYEVELNEATPGEERDTSSARAMTESLEAFTLGDVLPKDRRE +VLVDLLVRNTTGDDLIRAGVPEGWVVGDKTGSGGYGTRNDIGVLWPQEGDPIVLAVLSSR +DVEDAESDDALIAQASEVVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A3B8SMT9_PSESP +--ALTETVASIEARTGGHIGVSVTALESGQSW-SHRGDERFPIASTFKAFSCGHLLALAD +RDEVELDTRVRFDETDLQSYSPITKDRVGGSMSLFELCSATTSMSDNTAANLILRNTGGP +QGFTTFMRSIGDAVTRLDRYEPELNDVGPGEERDTTTPMAAARSLETLLLGDSLSTHSRE +QLKAWLVNNKVGGPLLRASLPEGWKIADRTGAGGYGSRGIIAVIWPQGSEPVIVAVYLTG +TTLTLEERDATIAEVGAALV--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S100 TaxID=1394638 RepID=A0A0I9QQ12_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQMDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSVGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAQISQLILERy +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI00096E0230 +---IDDQIAELERRHHALIGLYAANLDTGRTL-THRPDDMFAMCSTFKGYAVARVLQMAE +RGEISLDNRMFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMARS +QAHDAKAENPLIGELTALV---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TAA204 TaxID=1289387 RepID=UPI000D13861D +---IARALRELEREHSARLGVFAHNSVTGTSV-LYRADETFPICSVFKTVAVAAVLRDLD +QYGEFLAKRVRYTEQDVQDYAPVTGENLEGGMTVGELCAAAVSYSDNTAANLLLRELGGP +ASVTRFSRSVGDRATRLDRWEPELNSAEPWRTTDTTTPGAIGRTCARLTLGRALRPRDRK +RLTDWLLANTTGGARLRAGLPGSWTLADKTGTGEFGTTNDVGVAWKPDGTPLVLAVLSTK +DDAEAAADEPLIAKTAALLAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0004863000 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMAGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PDAAAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Woeseia oceani TaxID=1548547 RepID=A0A193LDU8_9GAMM +------LLLTLEQELDGTIGVFAMDTMTGNEL-AYRADERFAMASTFKSLLVAAVLAEVD +AGTLDLEERYGIDGVDMQSYSPVVGKLAPNEISLSELCAAAITISDNTATNMLLELIGGP +DELTQFLRRSGDDVTRLDRYETALNSNDKGDERDTTTPRAMTHSMYRLLTSDLLSSASKQ +RITEWLIASQTGFSRLRAGLPPGWTVGDKTGMGRNGAANNFAIAWPPGRKPVVMTVFMSW +SDTDVDTLNVAHARIAAHIAAAf +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium elephantis DSM 44368 TaxID=1335622 RepID=A0A439DZ72_9MYCO +--TVEARIAALERQHGALIGVYASNLDLQRTV-AHRAQERFAMCSTFKTYAAARVLQMAE +RGELSLEQSLFVDPADILINSPITEARAGGELTLAELCQAALQRSDNTAANMLLATLGGP +QAITAFARSIGDSESRLDRWETALNSAIPGDPRDTSTPQALGSGYRNLLAGDALAPPQRS +RLEDWMRANQT--SSMRAGLPDGWTSADKTGGGDYGSTNDVGIVYGPDGQRVLLALMTRS +QTSDAPGLRPLIGELTSLV---- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. PanSC19 TaxID=1520455 RepID=A0A3N1P3L8_9ACTN +-----ARLRRLEREHTARLGVFARDMRTGRTV-VHRAHERFPMASVFKTLAVAAVLRDLD +RDGEFLARRVHYTRAYVTKLSPIAGENVANGMTIAELCDATIRFSDNTAGNLLLEELGGP +TGITRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTTPYAIGLDHARLVLGDALDPHDRE +RLTDWMLRNTTSTEKFGRGLPADWILADKTGSPRYGGANDVGIAWRPDGTPIVLAVLSTQ +PEEDAPTDNPLVAGTAELLAEEf +>[subseq from] Beta-lactamase n=5 Tax=Stenotrophomonas TaxID=40323 RepID=B8LF98_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Moritella sp. Urea-trap-13 TaxID=2058327 RepID=A0A2I0FC53_9GAMM +--TLNDSLSAIELRTSGRIGAAVLDTENKQIW-HYNGDARFPMMSTFKTLACAKMLSASA +NGELNTSTKILLKSEALIPWSPVTKPLVGSSITVAQACEATMLTSDNTAVNIVLQHVGGP +EGVTAFLRDIGDNVTQLDRIEPELNEAKIGDVRDTTTPNAMVNTLNKLLFANVLSNRDKT +QLKTWMQDNKVSDPLLRSVLPPGWSIADRSGAGGYGSRGITAVIWHAERQPLIISIYLTE +TELSMAERNQVIAEIGQQILNQy +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Root264 TaxID=1736503 RepID=UPI0007C6B42A +--ALSRRLRDLERRYSARLGVFALDTATGRTA-EYRADERFPLCSVFKTLAAAAVLRDLD +HDGAYLARRIHYTEKDVTDYAPVTGENIAGGLTVEELCAAAVSESDNGAANLVLRELGGP +TAITRFCRSLGDRTTRLDRYEPALNSAEPWRRTDTTRPRAIGLTYARLVLGRALESADRR +RLTGWLIANTTNTERFRAGLPDDWTLADKTGGGQYGVANDVGVVWPPGRPALVLAVLSTK +HDPAGPTDNPLVAKAAALTA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces indicus TaxID=417292 RepID=A0A1G9IZJ9_9ACTN +----EAEFRSLEREFDARLGVFAVDTADGREL-AYHADERFAYCSTCKAFLAAAVLDKGG +--VGGLDREVAVRRADVEGWSPVTEKNIGSRMTLRALCDAAVRHSDNGAANALFHELDGP +RGLQRALRAIGDETTRCDRYEVELSEARPGDERDTSTPRALARSLRQYALGDVLDAEGRG +LLTDWLVRNTTGDKLIRAGAPDGWRIGDKTGNGSYGTRNDIALAWPPGGEPVVLAVMSRR +AGPDAEHDDALIARAAAAVFR-- +>[subseq from] Beta-lactamase PSE-1 n=97 Tax=Bacteria TaxID=2 RepID=BLP1_PSEAI +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGHSIFDVy +>[subseq from] class A beta-lactamase n=1 Tax=Lentzea violacea TaxID=128104 RepID=UPI000B7DBF74 +-----DALSELEKKFDARLGVYAMS-DNGSTI-EHRADERFAFCSTFKGLAAAAVLHRNP +--MSHLDTVVTYTEADLMKSSAITRQNVRTGMKLRDLCDAAVRYSDGTAGNLLLRDLGGP +AELTRYLRELGDTETRMDRVEPAITSATPGDPRDTATPRSLGTDYQRIVLGDALEPAKRD +FLTGLLERSVTGAKRVRAAVPAGSRVANKTGTGQYGTVNDIAVVWPPGREPVLIAIMSSK +STADAKYDEALVAEAAAYVVR-- +>[subseq from] Beta-lactamase class A CARB-17 n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A658HE08_VIBPH +-sQLNEDISLIEQQTSSRVGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRLEPRLNEATPGDNRDTTTPNAIVNTLRTLIEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLIAQISQLILQKy +>[subseq from] Beta-lactamase n=1 Tax=Salinicoccus halodurans TaxID=407035 RepID=A0A0F7HJ33_9STAP +-kNTDDAMGQIEKEYDANLGVYALDTGSGQTV-SYNADERFAYASTHKALAAGVLLQQND +--IEELGRTVEISEADLVNYNPVTEDYVGEAMTLEQLAEASLHYSDNTAGNLILEEIGGP +EGFKRALRDMGDDVTNPVRSEPNLNEFIPDDPSDTSTPRALTSSLKSLTVGDALPGEKQK +LLIDWLKGNQTGDTLIRAGLPENWEVGDRTGAATYGTRNAIAVIRPPGGEPIFLAVLSNK +DKKDAEYDDELIQRATEETI--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. ZAC14D2_NAIMI4_7 TaxID=2072405 RepID=UPI000D542986 +------NFAALEKASGGRLGVTVLDTGSGRRLgGHRQDERFPMCSTFKSILVAHILSLAD +AGRLSLDTRVPITERDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP +AALTAFLRAQGDPVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGDGLLPPSRL +QFADWLVDNQTGDACLRAGLGPRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG +ASVDEAQRAAVLARVGAL----- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. M71_S20 TaxID=592872 RepID=A0A498AP64_9ACTN +----HDRLAELERTFDARLGVYALATNTGDTI-VHRADERFAFCFTFKGLAAAAVLHRHP +--LSHLDTVVRYTADDLMKSSVITRRHVASGMTIRQLCDAAVRHSDGTAGNLLLRDLGGP +AQLTAYARSLGDAVTRMDRTEPAITTAIPGDARDTSSPRALGTTYQRIVLGDALPPEKRA +VLRDLLERNATGTQRVRAGVPRGWTVADKTGTGDYGTVNDIAVVWPPTSAPLVIAIMSSK +ATRDAEYQQALVAEAAAYVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CMB-StM0423 TaxID=2059884 RepID=A0A2K9FQ52_9ACTN +-qRATREFKELERAHDARLGVYAVDTRTGREV-AYRDGERFAFASTVKAFQAGAVLRQRK +--LSGLKKEITYDRSDLVANSPITEKHVDDGMTLGELCDAAVRYSDNAAANLLFEELGGP +KALQSFLRETGDDTSRMERIEPALSDWEPDSARDTSTPRALAGNLRAFVLGDVLGMPERA +RLAGWLRKNTTGDETIRAGVPKDWEVGDKTGTAAFGGRNDIAVVWRPDAAPLVMAVLSNA +TDRDAEPDDKLIAKAAAVVSD-- +>[subseq from] Beta-lactamase n=2 Tax=Mycobacterium montefiorense TaxID=154654 RepID=A0A2R5GX76_9MYCO +--QVDDRLAELERQYGAYIGLFATDVGSGRTL-AHREDEPFAMCSTFKAYAAARVLQKAQ +RGELDLQRPVFIDPAALLPNSPVTAPQAGKTMALAQLCAAALQRSDNAAANLLLTEIGGP +PAITDFARSIGDERTRLDRWEIELNTAIPGDPRDTSTPRALGTGFQKLLTGTVLGEAQRA +QLEQWMRDNMT--SSMRAGLPPGWTTADKTGAGAYGSTNDIGMVYGPTGQRVLLSLMTRS +QSPDADALQPLIAEVTKSVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium elephantis TaxID=81858 RepID=UPI000FE1AF4B +--TVEARIAALERQHGALIGVYASNLDLQRTV-AHRAQERFAMCSTFKTYAAARVLQMAE +RGELSLEQSLFVDPADILINSPITEARAGGELTLAELCQAALQRSDNTAANMLLATLGGP +QAITAFARSIGDSESRLDRWETALNSAIPGDPRDTSTPQALGSGYRNLLAGDALAPPQRS +RLEDWMRANQT--SSMRAGLPDGWTSADKTGGGDYGSTNDVGIVYGPDGQRVLLALMTRS +QTSDAPGLRPLIGELTSLV---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. PanSC19 TaxID=1520455 RepID=UPI000F4A0CD1 +-----ARLRRLEREHTARLGVFARDMRTGRTV-VHRAHERFPMASVFKTLAVAAVLRDLD +RDGEFLARRVHYTRAYVTKLSPIAGENVANGMTIAELCDATIRFSDNTAGNLLLEELGGP +TGITRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTTPYAIGLDHARLVLGDALDPHDRE +RLTDWMLRNTTSTEKFGRGLPADWILADKTGSPRYGGANDVGIAWRPDGTPIVLAVLSTQ +PEEDAPTDNPLVAGTAELLAEEf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. AU17457 TaxID=2015349 RepID=UPI000B79D31F +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGA +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMSVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDVLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAVLWPPSRAPIVMAVSFTQ +PDAAAAARADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=UPI000756FBBC +--AAQSDLAALEKASNGRLGVAALDTSNGARV-AHHARERFPLCGTYAVVAAAAVLARGS +LDATLLPRRILYRRYDVVAGSPVTENHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QTVTSFAHESGDTTFRLDHWEPELNAAAPGDERDTSTPVAMVDMLQRLLLGDLLREPQRA +QLIEWMVGGARGAAGIAAGVPPGWRVADKAGTGRYGTTSDVAVVWPPSRAPLVMAVSFTQ +PRADAAARADVVASAARIVAN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3N9H029_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMTGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PDAAAAARANVVASAARIAA--- +>[subseq from] Class A beta-lactamase n=2 Tax=Parvularcula flava TaxID=1566827 RepID=A0A6A8RTT3_9PROT +--------------NGGHIGVFARDIATGNSL-IHRADERFAMCSTFKWALAAQVLDEVQ +NGSITLDDEISFSEETLVPWSPVTGPLAAQGASIRTLCEAAVAVSDNTAANLLLRLVDGP +PGFTERLRGWGDEVTRLDRWETELNENAPGDPRDTTTPRAMAGLLERVAVGDIIAPAASA +TLRGWMEATSTGTNRLPAGTPDSWTLGHKTGTSNNGAVNDVGYFLRPDGAPIVIAVYVNA +PEAETTAAEVVIAEVAEMT---- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium persicum TaxID=1487726 RepID=UPI000C083946 +--DVQSRFAELEHTYAARLGVYVPASGATAAI-AYRADERFAFCSTFKGLLVAAVLHQYP +--LSHLDKVVTYTSADIRSTSPITQQHIATGMSIGQLCDAAIRYSDGTAANLLLAEIGGT +TAFTGYLRSLGDSVSRLDQEEPELNRDPPGDERDTTTPNAIALDYQQLVLGDALPADKRA +MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPTGVPHVVAILSDR +AGYDAEPSEALVADAARCVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf465 TaxID=1736385 RepID=UPI0006F4D2D7 +----GAALARIAGDLGGRAGIAVLDTSGGPAL-LHDAEGAFPLCSTFKLLLAAAILARVE +AGRERLDRRLAYGEADLDTYAPVTTRALRAGMSVEALCAAALVWSDNTAANLLLDALGGP +AALTAYGRSLGDPVTRLDRTEPDLNSAVPGDPRDTTRPAAMAATVGKILLGPSLTEASRA +RLEGWMTASRTGTKRLRAGLPADWGVGDKTGSGAYGTANVVALLRPPARAPLVAAIYLTG +SDTTSEARDAAHAAIGRVIAATy +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio rotiferianus TaxID=190895 RepID=UPI0002378115 +--KLNEDLAAIEQHIGGRIGVSVWNTQNDEHW-DYRGDERFPMMSTFKTLACATMLSDMD +SEKLDKNATAKVEERNIVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +NGVTRFLRSIGDGATRLDRFEPRLNEAKPGDKQDTTTPNAIVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSESLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPIYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI0011F29549 +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio metoecus TaxID=1481663 RepID=UPI000BA956EF +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] Beta-lactamase n=1 Tax=Nitratireductor sp. ES.061 TaxID=1855335 RepID=A0A1H4Q9G4_9RHIZ +--TLSQTVERIESTLGARVGIVIRDTGSDWRW-SHRAEERFLMNSTVKALICGGVLAELD +KGMLTLDQTLPIRQFDIVSYSPVTQKHVGKAMSIADLCLATLDISDNAAANLLIGRLGGP +KAVTAFLRSIGDPVSRLDRLEPKLNAFAPGDPRDTTTPAAMTETWHALLLGDVLKPASRT +QLIEWMSHGGVTGALMRASLPKDWAISDKSGAGSH-TRNLVAMVTPPGRAPFLVSIFISD +TDVDFETRNGALKDVSAAIVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. ORS 3257 TaxID=167468 RepID=A0A2U3QDE8_9BRAD +------ELETYERESGGRVGLYAENLVNGKKL-AWRADERFVMCSTFKASLAAFVLGRVD +RGEEQLAAMIPYGQADLLEYAPVARENLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP +AALTGFWRSLGDTTSRLDHDEPELNRSPPGNPQDTTTPAAMANNLRRLVLGEALSAQSRV +QLTEWMVNCKTGANRLRGGLPAGWKIGDKTGYNGKDAAGDIAVAWPKPDTPVLITAYVQG +GTPTPAKIAGVFAQIGRMVTD-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI0012453E24 +-sQLNEDISLIEQQTSSRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRLEPRLNEATPGDNRDTTTPNAIVNTLRTLIEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLIAQISQLILQKy +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium kyogaense TaxID=2212479 RepID=UPI000DABF7AE +-----DRLAALGRRHNARIGVYAVDLGSDRTV-EVGADDTFAMCSTFKAYASAAVLQRAQ +QGRLALTDAIAVQPSDIRPHSPVTEPRVGSTMTLAELCQAALQESDNAAGNLLLGTLGGP +PAITAFARSVGDDRTRLDRWETELNTAVPGDPRDTSTPRALGIGYRAMLTGDVLHVAHRQ +KLEDWMRANQT--SSMRAGLPDGWATADKTGSGGYGTTNDVGIAYGPQGQRWLLSIMTRS +ATPDADSLRPLIGEIAAAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. col6 TaxID=2478958 RepID=UPI0011CE87B0 +--AATARLRELERLHGARVGAFAYNVATGASV-RHRAGERFPMLSTFKTLAAAAVLRDLD +RDGEVLEKVVHYTKADCVSDSPVTDTHLASGLSVARLCDAAIGDSDNTAANLLLRELGGP +TAVTRFARSLGDRVTRLDRWEPLLNSAEPGRVTDTTTPSALARDYARLVLGNALEPRDRE +RLTYWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYASCNDVGVAWTPEGVPVVLAVLTTK +PASDAAGDHPLVRDAAKALA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia seminalis TaxID=488731 RepID=A0A103KGS4_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEVVSGSPITESRVDTGMTIAQLCEAMLQAGDKGAGNLLMGVLGGP +QAVTSFARESGDTTFRLDHWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLHEPQRT +QLTEWMAGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +QRADAAARADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. BH-2-1-1 TaxID=1905847 RepID=UPI0011A19B6F +---TRQAFADLERRDGARVGVVAVDTGTGRSL-GYRADERFAFASTNKVQIAAAALAASS +--PADLDEVVHYDRGDLLSYAPVTTPAVDTGLTVRQLVDAAIRQSDNTAANLLVERVGGV +AGMTRWLRGLGDTTTDVSRTEPDLNTALPGDRRDTTTPAQSAADLRAVLLGDALDADDRS +LLRDAMLGTTTGATTIRAGVDPSWTVADKTGTASYGVRNDVAVVTPPGRDPIVLVVMTAH +GTADAEPSDALVAEATRIAIAH- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3N8YP19_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGA +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMSVLGGP +QAVTAFARECGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDMLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPSRAPIVMAVSFTQ +PDAAAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=2 Tax=Vibrio cholerae TaxID=666 RepID=A0A5C9HMU4_VIBCL +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACLATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0007473BC4 +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. DBP42 TaxID=2545267 RepID=UPI00110CE5B2 +----DDGIAELERRNNAFIGMYASNLDSGRTL-THRADEMFAMCSTFKAYAAARVLQMAE +HGEVSLENRVFVDREAIVPNSPVTETRAGGEMTLAQLCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPSALAVGYRAVLAGDALSPPRRR +LLEDWMRANQT--SSMRSGLPEGWTTADKTGSGDYGSTNDAGIAFGPEGQRLLLVMMTRS +QA-DDPKAEPLIGELTA------ +>[subseq from] Beta-lactamase n=4 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QE58_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium asiaticum TaxID=1790 RepID=A0A1A3KUR9_MYCAS +--DLSHQFDQLERRYEGRLGVYVPE----PGI-AYRADERFAFCSTFKAPLAAAVLHQYP +--LDHLDKLVSYRKSDINSVSPVTEQHVDTGMTVGQLCDAAVRYSDGTAANLLLAEVGGP +AGFTTYLRTLGDNVSRLDQPEPQLNRDAPDDPRDTTTPHAIALVFQQLLLGDALPADKRA +LLVDWMTRNTTGGKRIRAAFPPDWKVADKTGSGDYGRTNDVAVVWSPSGAPHVIAIYSDF +VGYDAQPNEGFVADAARIVAS-- +>[subseq from] class A beta-lactamase n=1 Tax=Herbidospora cretacea TaxID=28444 RepID=UPI000774458B +----VADLRALETSFKGRIGVYAVDTATGRTV-AYRSGERFPLASTFKGVLAAAVLDKEP +---DILGKRILIKKKDLLAYSPETEKHVGSRMTVAELARAAVTKSDNAAANLLLKEVGGP +KGLTRYFRGLNDHVSRLDRTEPGLNQWSPAEVRDTTTPAAIAADLRVLTVGNALDAGDRR +KFTGWLVANETGDKRIRAGLPKSWRIGDKTGTGGYGTANDYAIIWPKGSKPIIMAIYTNR +TARNGTADDSVIARAATIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Amycolatopsis sp. KNN50.9b TaxID=2018303 RepID=A0A229TP23_9PSEU +-----VSFADLESRFDSRLGVYAIDTGTGREI-AHRADERFNYASAIKSLLAGAVLRRNV +----DLDKVVTYTDADIQPNSPITKDR--RSVTVCEAAEAALLQSDNTAANLLFAEVGGP +AGLAAVLREIGDTTTHPDRLEVELNSAIPGDIRDTSTPRAMAGSLRAFLLGDALPADKRD +LLVGIMRRNRTGAELIRAGVPSEWPVADKTGTGDYGTRNDIGVIWPPTGAPIVLALMSSR +GTPDAEHDNKLLAEAASRVVD-- +>[subseq from] Beta-lactamase n=2 Tax=Pseudomonas TaxID=286 RepID=L0FSL3_PSEPU +--KLIQAVQAEESALQARVGMTVFDENTGTTW-NYRGDERFPLNSTHKTFSCAALLAKVD +GKSLSLSQSVSISKEMLVTYSPITEKSLSPEVTLGRICQAAVSYSDNTAANVVSNAIGGA +TGFNAYMRSIGDEQTRLDRKEPELNEGTPGDVRDTTTPNAIVNSLRKILLGDGLSVSSRS +ELTQWMLDDQVAGALLRASLPSDWKIADKTGAGGYGSRSIVAVIWPPSKQPLVVGIYITQ +TKASMQASNQAIARIGVV----- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora citrea TaxID=47855 RepID=A0A1C6TRH4_9ACTN +------RLTELERKYGARLGVYALATGTGATV-AHRADERFAFCSAFKGLAAAAVLHRNP +--LSHLDTVVRYAERDLMKSSAITRRHVATGMTVRQVCDAAVRFSDGTAGNLLLRDLGGP +AELTAYVRGLGDTVTRMDRFEPHIVTAVPGDLRDTTSPRAIGTDYQKIVLGDALPPDKRA +FLRGLLERNATGARRIRAGVPKGWTVADKTGTGDYGTVNDIAVVWPPQAAPLVVSIMSSK +AARDAEYDQELLAEAAAHVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F599D6F +--TAHAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTSFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PDAAAAARADVVASAARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cenocepacia PC184 TaxID=350702 RepID=A2VYA7_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTSFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMTGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PDAAAAARADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora sp. MBT63 TaxID=1444768 RepID=UPI00068F131A +--DVTRALAGLEREHSARLGVFARNTVTGAQV-LYRAHELFPICSVHKIVTAAAVLRDLD +HHGEFLARRIRYTAEDVAAYAPITGEHLASGLTVAELCVAALDYSDNAADNLLLRELGGP +AAVGRFCRSVGDGVTRLDRWEPALNSAEPGRVTDTTTPAAIATTLTALVLGGALTSRDRR +RLTDWMLANTTGAARLRAGLPQPWALADKTGTGDYGTTNDVGVAWTADGAPVVLSVLSTK +TDPHAPADEPLIARTAALLV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A4Q6CB32_9PROT +------DFEKLERETGGRIGVSVLDIRTGKRI-LYRSGERFPFCSTFKTIAVATALKHGD +-----LSTRLTFTSDDVKKYAPITTKFVDRGMTVSELSEAAIQYSDNAAVNILMRNLGGL +QAVNTFAREIGDEVFQLDRWEPELNSAEPLDKRDTTTPDAMTGSVHKILLGDALAAFARD +LLLSWHIGNTTGDKRIRAGLPKGWTAAEKTGTCSHGTTNDAGVIWRPDGSPIVLTIYLTG +RAKDAKPDDAAVARATQIIVE-- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio metoecus TaxID=1481663 RepID=UPI000BA9192D +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEVKKADLVTYSPVLEKRVGKPITLSDACFATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] Beta-lactamase n=1 Tax=Jiangella sp. DSM 45060 TaxID=1798224 RepID=A0A1H2CL98_9ACTN +--AVAAALTALEDDYAARLGVYAIDTGTGQVV-EHRPDERFAFASTHKMLSAAAVLQVTE +--PADLDELIEVDPAEVVGWSPVTEPAAGVGLTLLEIIEAAITLSDNTAANLLFEQVGGP +DGLEAAVRGFGDETTSFDRIEPGLSDWAPGEERDTTTPRAMAGNLRDLLLGDLLTDEDRT +LLHDTMRANTTGDELIRAGVPDGWVVADKTGSATHGGRNDVAVIEPPGAAPIVLAVYSNR +LDPEAESDPALIAAATEIVVDAf +>[subseq from] Beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=A0A454BGN4_VIBHA +--KINEDLAAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLNDMD +NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSVGGP +RGVTMFLRTIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEDDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITG +TDLSLQARDQVIAQISQLVLEEy +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LF88_STEMA +-----ADYAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRYDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=[Actinopolyspora] iraqiensis TaxID=52698 RepID=UPI0003F515F9 +-----PDFAELERRYSARLGVYALDTGSGTEI-THRADERWAFCSTIKPFTAMAVLQRTT +--LDGLDEPITYSREDLISHSPVTEQHVDTGMTLRAVLEAAVRNSDNTAQNLLLDEVGGP +AGLQRALRELGDTVSHADRYEPELNETAPGDIRDTSTPRALATNLRKLVLGDVLAPGKRT +ILREAMRNPPLTADLIQAGVPDDWQVEDKSGAGGYATRNDIAVLYPPERAPIVLVVLSDR +ARPDAEYDDTLLAEAARVTV--- +>[subseq from] Beta-lactamase n=1 Tax=Salinisphaera japonica YTM-1 TaxID=1209778 RepID=A0A423PT43_9GAMM +-----ARMKTLEARHGGRLGVSVCDTTGARRL-SHRGDDRFLLCSTVKLPLAALILSRMD +AGQESLERHIDYTRADLVTYSPETEQHVATGMTLGAICRAGLTQSDNTAANLMFAAVGGP +AALTDFIRALGDATTRSNRLETALNEP-TLNAKDTTTPNAMRGLMTRILLGDVLSHGARA +QLLTWMQANQTGDHRLRAGLPSAWRIGDKTGSGGDNTAADIAIIHPGAGHAIVVSAYYAG +SRASGEARDRVLADVGRAVAELy +>[subseq from] Class A beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. SID9727 TaxID=2706114 RepID=A0A6B3BAQ6_9ACTN +----TARLRELERTHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD +RDGEVLEKVVHYTKADCVSDSPVTDTHIASGLSIARLCDAAIGDSDNTAGNLLLRELGGP +RAVTRFAHSLGDRLTRLDRWEPDLNSAEPGRITDTTTPSAIARDYARLVLGDVLERRDRE +LLTHWLLHCRTSGTRFRAGLPPEWTVADKTGGGSYASCNDVGVAWTPEGAPVVLAVLTTK +PASDAAGDHPLVLDAARILA--- +>[subseq from] Beta-lactamase n=1 Tax=Gammaproteobacteria bacterium HGW-Gammaproteobacteria-11 TaxID=2013793 RepID=A0A2N1ZCB1_9GAMM +--ALTDTVAFIEATTGGRVGVSITDLDSGLTW-SHRSNERFPMASTFKAFSCAHLLALAD +KGEIDLDSRVQFEESDLQDYSPITQHRVGGNMTLFELCAASTSLSDNTAANLTLQNTGGP +PAFTQFMRSIGDNTTRLDRYEPDLNYVGPGEEQDTTSPASAAKSLQTLLLGNSLSNNSRE +QLKTWLINNEVGGPLLRASLPDGWQIADRTGAGGYGTRGIVAVIWPQTHGPVVAAVYLTG +TTLTLEERNAAIADIGRALVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. Root151 TaxID=1736475 RepID=UPI0012E36F4A +-----SEVAAIERRYDVTVGLSATHLRSGRTM-QHRADAPAAMCSVFKALAAAAVLRDHD +RRGETLDRRVFYPPADVLIHTPETGRHVDDGMTIRELCDAALRFSDNAAGNLLLREIGGP +RGLTAFLRSVGDGVSRLDRWETELNSALPGDPRDTTTPAAIARTYAGLLIGDTLSRRDRT +TLRDWMLANQTSDNRFRAGLPEGWILADKTGGGDYGSNNDVGVAWNPRGEPVVIAALVRG +KVADAVTPDVVHAELAALVAD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Pararhizobium antarcticum TaxID=1798805 RepID=A0A657LTM1_9RHIZ +----GVRLAALEKKTGGRLGVSVLDTETNIGF-DYRETERFPMLSTFKTLAAACVLAGIK +DDEDALQRRVKFSKADLVSYSPGTEAFADGEMTLSALCDAAITLSDNTAGNLLLAEIGGP +QGLTAWLRSIGDATTRLDRTEPTLNESLKGDPRDTTTPAAMRETITTLLAGDVLSPSARD +RLLGWLVANKTGDARLRAGLPAGGLVGEKTGTTDKGGACDVGLFRPERRQPIFISAYVAE +ASVPVKDLNPVFAEIGRMV---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI00073AD3D3 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGL +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium porcinum TaxID=39693 RepID=A0A1Q8XTF8_9MYCO +---VDDQIADLERRHNALIGLYASNLDSGRVL-TRRPDEMFAMCSTFKGYAAARVLQMVG +RRQISLDNRVFVDREAIVPNSPVTETHVGGEMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPTALAVGYREVLAGDALSPPQRR +LLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPDGQRVLLAVMTRS +QADDADNLRPLIGELTAVV---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02923 TaxID=1718985 RepID=A0A1Q4VI00_9ACTN +--AATRRLHELEREHRARIGVFALNLATGASL-LHRAHELFPICSVFKTLAVGAVLRDLD +HDGTQLSRVIHYTEADVRKHTPVTSQHVADGMTVRALCDASIRYSDNCATNLLLRELGGP +PAVTRFCRSLGDPVTRLDRWEPELNSAEPGRRTDTTSPYAIARTYRRLVLGDALNGPDRA +LLTDWLVRSTTSVERFRAGLPKDWTVADKSGSGSYGTSNDVAVAWTPDGTPIALAAFTHK +PAL-------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=J9UVY5_ECOLX +-------IKLSESQLSGRVGLIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGI-------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q9F4G6_PSEAI +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNSNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGHSIFDVy +>[subseq from] Uncharacterized protein n=1 Tax=Aeromicrobium endophyticum TaxID=2478914 RepID=A0A3L8PPK9_9ACTN +-----------ATAAGIDFGVSVTDLSSGASM-SIGSQEPVKAASVIKLPLLAALMAEAD +RGTLSLDEVVTIEASNIVGGSGTLRDETPLDITVGELMELMVQVSDNTATNVLIDRAGGF +DAVNAYIESLGFEHLWLGRKMI--HPATPPLQENWITSGEVTELLRMLHADEILSPASSE +HIIELMKGQLV-DTKFGAVVPRD-VLANKTGELAD-VSHDSGYILVPGRE-VALTVTTAF +GDLTRAEVDQYVQRAASIVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Aeromicrobium endophyticum TaxID=2478914 RepID=A0A3L8PPK9_9ACTN +---------DAAAEAGIDIGVAIEDLSDDQQL-LLGAQDRFTTASTIKMSLAATVMHQVE +RGMLSLDDVVTITEDERYGGSGSLKDNPFPQVSVGTLLDLTVTISDNTATNKLVDVVGGF +DVINALTQAVGIAKEDLHFGRKMFGPIVPPDGDIWLTPHGVNQLMVLFYDGEFMSAESAQ +FIIELMLSQQV-KTKLGATIPAE-VLAHKTGENDT-VSHDIGMVLLPGQ-EITLSVFSRG +LPDVQATANPYLQQIGAAVYAY- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=UPI000F800387 +--AAQAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPVCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP +QAVTSFAHESGDTVFRLDRWEPELNLAAPGDERDTSTPVAMVDTVQQLLLGDTLREPQRA +QLIEWMSGGTRGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAVRIAT--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium novocastrense TaxID=59813 RepID=A0A100ZAU6_9MYCO +---VEDRLGEMERRQNALIGVFATDLGTGRTI-AHRAQDPFAMCSTFKTYAAARVLQKAE +RGELALTDRVTIEPGDIVPNSPVTEAHVGQTMTLAQLCQAALQRSDNAAANWLLRVIGGP +SGVTDFARSIGDQRSRLDRWEIELNAAVPADPRDTTTPEAIGAGYRSILTGNVLAEPQRR +QLEDWMRTNQT--SSVRPVLPPGWATADKTGSGDYASTNDVGIAYGPAGERLLLAIMTRT +AAPDAPNDRQLVGEVAAALVA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A1R1JCL5_9BURK +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAALLARSA +LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGASGCA +QLTKWLLGSANGVAGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADASPRADVIAEAARIAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=B6E3J9_SALTM +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGHSIFDVy +>[subseq from] Beta-lactamase Toho-1 n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A095FRL5_BURCE +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNQATPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGNGGFGTTTDIAVLWPPSRAPIVMAVSFTQ +PEAAAAARADVVAAAARIAA--- +>[subseq from] Fri1 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A0M5L4T8_ENTCL +-----EEMRELETSFGGRIGVYILNPKNGKEF-AYRQDERFPLCSSFKAFLAASVLKRTQ +EKSVSLDDMVEYSGRVMEKHSPVSEKYRKTGASVQTLAKAAIQYSDNGASNLLMERIGGP +EGLTAFMRSTGDTDFRLDRWELELNTAIPGDERDTSTPKAVAMSLKNIAFGSVLDAKNKS +LLQEWLKGNTTGNARIRAAVPDKWVVGDKTGTCGYGTANDVAILWTDANSPAVMAVYTTR +PNQNDKHDEAVIKNAAKIAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=UPI000160DAC5 +--DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD +RGTENLTAQIEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLMERIGGP +EGFTDYMQTSGDLITRLDRWETDLNSATPGDPRDTASPRSVLSTLHAALSGTMLSGSSSA +QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE +TNADFSRRNQAISDIGRAMI--- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea turkmeniaca TaxID=103838 RepID=A0A5S4FB52_9ACTN +--NVRKELRALEKAFKGRIGAYAVDTATGKTV-TYRAGERFPLLSTFKAMACAAVLHKAR +TDPGLMNKVLHWTADEVLDYSPVTEKHVKDGLTVAQLCEATITLSDNTAGNLILKQIGGP +AGLTEYFRSLKDPISRLDRYEPGLNDWTPKDKRDTTTPAAIARDLRALTSGNALHAKDRE +QINTWLIATRTGDARIRAGLPKTWTIGDKTGTNSTGGGNDIAVIWPEKGAPIIMAIYTNR +TP-GLATDDKTIAKTATILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008420A6A +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANSVKGIRAGVPSDWRVAGKAGTGGYGTMTDVAVLWPPSRAPLVIAASFTQ +PGADAAPRADVIAEAARIAA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Microcella putealis TaxID=337005 RepID=A0A4Q7LTV8_9MICO +----DDDLSSLEAAYDARVGVYALDTGSGDRV-AYRADERFAYASSIKAVLAAAILQEVD +----DLDRVVSYGADALVANSPETEANLATGMSIRDLAEAAVRVSDNAATNLLLAELGGP +AAFGELLASLGDTTTEPARTEPALNEATPGDTRDTSTPRALVETLRAYALGDALPDDRRA +LLIDWMTGNATGDTLIRAGAPADAVVADKSGAGGYGTRTDIAVVWPAEGDPIVIAVLSSR +AEAGAERDDQLVADAAAVALD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces scabiei TaxID=1930 RepID=A0A086GY44_STRSC +---LARQLGELEREHAARLGVFAHDTATGHTL-AYRADERFPICSVFKTLGAGAVLRDLD +RDGEYLAKRIHYTKEYVEAYCPITARNVAAGMTVGELCSASVSHSDNGAANLLLRELGGP +TAITRFCRSLGDRTTRLDRWEPQLNSAEPWRKTDTTTPRAIGGTYARLLLGRALPDADRE +LLTDWLIANTTNVERFRAGLPADWTLADKTGGGSYGVANDVGVVWPPLRPPLVLSVLTTK +HAPEGPSDNPLVAKVAGLVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CB02923 TaxID=1718985 RepID=UPI0009A10CED +--AATRRLHELEREHRARIGVFALNLATGASL-LHRAHELFPICSVFKTLAVGAVLRDLD +HDGTQLSRVIHYTEADVRKHTPVTSQHVADGMTVRALCDASIRYSDNCATNLLLRELGGP +PAVTRFCRSLGDPVTRLDRWEPELNSAEPGRRTDTTSPYAIARTYRRLVLGDALNGPDRA +LLTDWLVRSTTSVERFRAGLPKDWTVADKSGSGSYGTSNDVAVAWTPDGTPIALAAFTHK +PAL-------------------- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI0008932FD7 +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP +KRITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. MSMB1826 TaxID=1637875 RepID=UPI0007547163 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNQATPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGNGGFGTTTDVAVLWPPSRAPIVMAVSFTQ +PEAAAAARADVVAAAARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=A0A124RKU1_9BURK +----QAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGA +LDASLLPRRILYRRYEIVSGSPITESRVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PEATAAARADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis ruanii TaxID=944491 RepID=UPI000E288BA3 +-----VSFADLESRFDSRLGVYAIDTGTGREI-AHRADERFNYASAIKSLLAGAVLRRNV +----DLDKVVTYTDADIQPNSPITKDR--RSVTVCEAAEAALLQSDNTAANLLFAELGGP +AGLAAVLREIGDTTTHPDRLEVELNSAIPGDIRDTSTPRAMAGSLRAFLLGDALPADKRD +LLVGIMRRNRTGAELIRAGVPSEWPVADKTGTGDYGTRNDIGVIWPPTGAPIVLALMSSR +GTPDAEHDNKLLAEAASRVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas borealis TaxID=2508710 RepID=UPI00109FC74C +--DLERPLGELERSADDRVGVALMNVATGAVA-SHRGHERFLFNSTCKFFIAAAVLARVD +EGRETLERRIVIEEGDLVGWTPVTEKRLGEPLTVAELCQAAVAWSDNAAANALIESVGGP +AAVTAYLRSIGDDTTRLDRVEPDLNTDREGDERDTTTPLAMMATLRTLMLGDALAPSSRH +QLAAWMIEGKTGDARLRAGMPASWLVGEKTGTNGEGNASDVGIAWPGDRGAVVAVAYTKM +PGATGGQRDETIATIGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. PhB130 TaxID=2485178 RepID=UPI000F4BE663 +--SADASFRRLEQQHDARLGVVAVDTGSGHRV-EYRQGERFAFASTNKTFIAAAVLAGAS +--DTDLETVVHYDRSDLLDYAPITSRFVDTGMTVRELIDASLRFSDNTAANLLVERLGGP +DSVERYLRGIGDRVTNVDRVEPELNEATPGDARDTTTPAQFATDLRKVVLGTTLELTDRT +FLRDTMLDNTTGAGTVRAGVDPAWPVADKTGTGEYGVRNDIAVVYPSGRAPLVVVVMTSG +KQSDATADDALVAAATKAAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas TaxID=286 RepID=UPI0009410562 +--KLIQAVQAEESALQARVGMTVFDENTGTTW-NYRGDERFPLNSTHKTFSCAALLAKVD +GKSLSLSQSVSISKEMLVTYSPITEKSLSPEVTLGRICQAAVSYSDNTAANVVSNAIGGA +TGFNAYMRSIGDEQTRLDRKEPELNEGTPGDVRDTTTPNAIVNSLRKILLGDGLSVSSRS +ELTQWMLDDQVAGALLRASLPSDWKIADKTGAGGYGSRSIVAVIWPPSKQPLVVGIYITQ +TKASMQASNQAIARIGVV----- +>[subseq from] class A beta-lactamase n=1 Tax=Acuticoccus kandeliae TaxID=2073160 RepID=UPI000D3E1605 +--RLADTIARIESGLDARVGVLVRDSATDWEW-GHRSDERFLMASTFKSVLCGAVLARVD +AGDLSLSEPLAVRKAAMIAHAPVTEKHVGGTMSIGELCFATLDMSDNPAANILVERLGGT +GAVTAFARALGDPVTRLDRLEPELNLFEPGDLRDTTSPEAMLFIWEAMLRGDALSPASRA +QLDAWMSEGGVTGKLLRASTPDDWAVADKSGAGRDHTRNLVAMVTPPGRDPYFVAIYLSD +SPADFAARNAAVAQIGKAVVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Nocardioides sp. Root151 TaxID=1736475 RepID=A0A0Q7ZQ10_9ACTN +-----SEVAAIERRYDVTVGLSATHLRSGRTM-QHRADAPAAMCSVFKALAAAAVLRDHD +RRGETLDRRVFYPPADVLIHTPETGRHVDDGMTIRELCDAALRFSDNAAGNLLLREIGGP +RGLTAFLRSVGDGVSRLDRWETELNSALPGDPRDTTTPAAIARTYAGLLIGDTLSRRDRT +TLRDWMLANQTSDNRFRAGLPEGWILADKTGGGDYGSNNDVGVAWNPRGEPVVIAALVRG +KVADAVTPDVVHAELAALVAD-- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Nocardioides TaxID=2615069 RepID=A0A0Q7QVX4_9ACTN +-----SEVAAIERRYDVTVGLSATHLPSGRTM-QHRADAPAAMCSVFKALAAAAVLRDHD +RRGETLDRRVFYPPADVLIHTPETGRHVDDGMTIRELCDAALRFSDNAAGNLLLREIGGP +RGLTAFLRSVGDGVSRLDRWETELNSALPGDPRDTTTPAAIARTYAGLLVGDTLSRRDRA +TLRDWMLANQTSDNRFRAGLPEGWILADKTGGGDYGSNNDVGVAWNPRGEPVVIAALVRG +KVADAVTPDIVHAELAALVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Comamonas testosteroni TaxID=285 RepID=UPI0005B48245 +--TLSDELAGLEIQSQGRLGLHVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARVLYLAQ +RDDIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVVVSDNTAANMMLEASGGP +AALTQWLRELGDGTTRLDRNEPSLNTALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA +LLQQWLADSRTGDKRVRAGMPGDWKVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG +SPLDGAGREAVLARAGEAIK--- +>[subseq from] Beta-lactamase n=2 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=A0A506Z6T7_MYCFO +---IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYVAARVLQMAE +HGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS +QAHDP-KAEN------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID1034 TaxID=2690248 RepID=A0A6B1NPR5_9ACTN +--DVSGALRQLEAAHDVRIGAYALDTGTGRTV-SYRGNESFPSLSTFKAMACAAVLDRAR +HEPGLLDKVVHWKASDEVANSPVTKGQGGKGMTVAELCRAAITQSDNTAGNMVLHQIGGP +QGMTRYYRSLGDPVSRLDRWEPELNDWQPGERRDTTAPASMGRDLAKTSLGRGLAPADRD +TLNTWLRATVTGGERIRAGLPKDWTVGDKTGTTDYGSANDIAVAWPKSGHPVIIAIYTNH +AVAQAPADNAVIASTASTLV--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. MTM3W5.2 TaxID=1805827 RepID=A0A1P8YIE9_9NOCA +-qSLDTKLDALEARYATRIGVTAIDPATGQIY-QHRGDERFALCSTFKTYAVAEVLRRTR +AGTSSLDKSVLVEPGDLVENSPITAAAVGTPMTLRQIAEAALTRSDNTAGNYLLEEIGGP +PAVTSLAREIGDESTRLDRWETELNSALRGDPRDTSTPNDLADGYRALLLGDALGSPERA +QLVDWMRASKTSDKRIRAGLPEGWTAAAKSGAGRFGTVNDAGVAWDRDSNPLVLAILTDS +LTEDAQGNNQVVADTTAAVVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A3KEX9_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVLTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. CNPSo 3157 TaxID=2654983 RepID=UPI00128DD1E1 +---AHERFEQLEARSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLAVAAILKRSI +AERALLDTHIRYGETDLVANSPVTKRHLSEGMSMGDACAAALQYSDNTAANLLLTALGGP +EVLNEFARSIGDTWFDLVRREPELNDAVPGDMRDTTTPRAMMHDMQKILLNDVLEPPQRE +KLKAWLLGNTTGERRIRAAVRSGWPVADKTGSGDYGTANDVAVVYSPAAA-FVVAVYFTG +VTKETPPQNEIVDEAARIVFD-- +>[subseq from] Beta-lactamase n=1 Tax=Litoreibacter sp. LN3S51 TaxID=2599296 RepID=A0A5B8I8Y7_9RHOB +--TLADTVAQVEERLGARIGLSLVDTGSELSW-LHREDERFLMNSTVKTPLCGTVLARRD +AGRLSLSDTLRVTQEDILSYAPVTAEQVGTEMTLADLCLAALDMSDNTATNMLIDYLGGP +QAVTEFFRTTGDEVSRLDRREPELNTLVPGDPRDTTTPAAMTSTLRRLLLGDVLSPSSRD +QLAEWMSLGGVTGNLLRADAPDDWLILDKSGSGNH-TRNIIAVITPDGGSPWIATIFISD +TDADFATRNAALQEIGSAVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F5AF6AC +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTSFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMAGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PDAAAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. Leaf125 TaxID=1736265 RepID=A0A0Q5E821_9RHIZ +----GAALARIAGDLGGRAGIAVLDTGGGPAL-LHDAEGTFPLCSTFKLPLAAAILARVE +AGRERLDRRLAYGEADLDTYAPVTTRALRAGMSVEALCAAALVWSDNTAANLLLGALGGP +AALTGFCRDLGDPVTRLDRTEPDLNSAVPGDPRDTTRPAAMAATVGKILLGPSLSEAGRA +RLKGWMTASRTGTKRLRAGLPADWGIGDKTGSGAYGTANVVALLRPPARAPLVAAVYITG +SDATSEARDAAHAAIGRVIATAy +>[subseq from] Beta-lactamase class C n=1 Tax=Burkholderia sp. 28_3 TaxID=2183921 RepID=A0A364H505_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLPPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F5B447D +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTSFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMAGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PDAAAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium aphoticum TaxID=754436 RepID=A0A0J1GNG3_9GAMM +---VQTQIQAIEQTLSAHIGVAVLDTQNNTRW-SYKGDERTPLTSTFKTLACAKLLHDAE +NNTLALIDTVTIKASELVTYSPVTEKWVGKAIPVVQACEATMFTSDNTAANIVIHAVGGP +DKITAFLRQSGDAVTQLDRFEPALNEATLGDVRDTTTPNAMTQTLNTLLFKNGLSKQNQQ +QLIDWMVGNQVTGNLLRSVLPQGWTIADRSGAGGHGARSITAVVWPEDRAPVIIAIYVMQ +TEASFDARNQAIVTIGQAIFNLy +>[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea sp. SBT364 TaxID=1580530 RepID=UPI00066E12DD +--SAKKELRALEASFRGRIGAYAVDTATGKTV-AYRSGERFPLLSTFKAILCGAVLHKAR +TEPGLMDKVLRWTSDDLVAHSPVTEKHVKDGLTVAALCEATITTSDNTAANVLLKEIGGP +GAVTRYFRTLKDPISRLDRTEPTLNDWAPKEKRDTTTPAAAARDLRALTAGSALHAKDRE +RLNAWLIANQTGDARIRAGLPRTWRIGDKTGTNGRGLANDIAVVWPAKAAPIIMAIYTNR +ADPADAVDDKIIAGTATILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Comamonas thiooxydans TaxID=363952 RepID=UPI00050F2EE9 +--TLSDELAALEIQSQGRLGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ +RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQDLCEAMVLVSDNTAANVLLEASGGP +AALTQWLRELGDGTTRLDRNEPSLNTALPGDERDTTTPQVMVQSLQKLLLGDVLEGYARA +LLQQWLVDSRTGDKRVRAGMPDDWTVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG +SPLDGAGREAVLARAGEAIK--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A72A19 +-----NELASLEKDFVGRIGVYALDTGSGDTV-SHRTDERFLMCSTVKTFIVSAILHRSL +SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP +KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSGGRD +LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP +EDPTSTKGKPTIAAAARIVLRAf +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces mobaraensis TaxID=35621 RepID=A0A5N5W933_STRMB +---VAERLRALEEAYHGRIGLAAFDTGSGRAV-TYRAHERFALCSTFKFLAAAAILDKAR +RDPGLLDRPVHYA--EVIDGSPVTKDNLPRGMTVRELCDATIAVSDNTAGNLLLEQLGGP +RAIGAFARTLGDRRTRLDRTEPTLNTNLPGDPRDTTTPAAMARDVYALTVGTALAAPDRE +QLNRWLEGCRTGDARIRKAMPAGWLVGDKTGTGERGAANDIAVVRPPGRAPLVVAVYTTR +VGGTETGDSEIIARAAGM----- +>[subseq from] class A beta-lactamase n=1 Tax=Lentzea kentuckyensis TaxID=360086 RepID=UPI000A3D379B +-----EALFELEKKFDARLGVYAAGVG---TI-EHRADERFAFCSTFKGLAAAAVLHRNP +--MTHLDTVVTYTQADLMDSSKITSRHVQTGMKLRDLCDAAVRYSDGTAGNLLLREVGGP +AELTRYLRELGDNETRMDRIEPDITSATPGDPHDTATPRSLGTDYQRLVLGDALEPEKRD +FLRDLLERSVTGAKRIRAGVPQGSRVASKTGTGDYGTANDIAVVWPPSREPILIAIMSSR +SSADAKYDEALIAEATAYVAK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces rimosus subsp. paromomycinus TaxID=92743 RepID=A0A401WG83_STRRY +-----------EREYGARLGVYALATGTGATV-VHRADERFAFCSAFKGLAAAAVLHGNP +--LSHLDTVVTYTEDDLMKHSPITGKHVSTGMSIRRLCDAAVRYSDGTAGNLLLRDLGGP +GKLTAFARGLGDPVTRMDRTEPAITQATPGDPRDTTSPRAFGTDYRKLVLGTVLPADKRE +FLRDLLVRNATGAQRIRAGVPKDWVVADKTGTGDYGTLNDIAVAWPTGSPPLVISIMSSK +PAKDAAYDQRLLARAAEYVVA-- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI000BA8F8BF +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] Beta-lactamase n=1 Tax=Sulfitobacter pseudonitzschiae TaxID=1402135 RepID=A0A073J4Q4_9RHOB +--ELEQTVDRIEARLGGRIGIALVDTGSDFTW-ANRPDEQFLMNSTVKVPLCGAVLARVD +AGTLSLTDELPVTEGDIVTYAPVTEQHVGQSMNMAALCLAAIDMSDNTAANLLIEHLGGP +QAITQFFRSTGDIESRLDRFEPELNTFTPGDPRDTTTPVASADTVRNLLLGDVLSENSRK +QLADWMRHGGVTGKLLRAGAPADWQIYDKSGSGSH-TRNLVAMVIPDGRAPWIVSIFISD +IDADFETRNAALQDISRAI---- +>[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica subsp. enterica serovar Tallahassee TaxID=356544 RepID=Q2I724_SALET +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLSKFLFGSALSEMNQK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGHSIFDVy +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=A0A378UA58_MYCFO +---IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYAAARVLQMAE +HGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS +QAHDP-KAEN------------- +>[subseq from] Beta-lactamase n=1 Tax=Tardiphaga sp. CF115 TaxID=2135486 RepID=A0A370QTH6_9BRAD +---APAALQAYERDTGGRIGVYAENLKTGAKI-AWRANERFVMCSTFKASLAACVLARID +RGEDKPDQMISYAAADLLEYAPVARDNLAKGLSVADMCKAIVELSDNACANMLLARVGGP +AALTAFWHRTGDSVSRLDHNEPLLNRSRPGNPQDTTTPAAMAGNVKRFVTGDVLTPASRA +QLTDWMVNCKTGDKRLRAGLPKTWKIGDKTGNNGKDAAGDIAVTWPKPDQPVVIAAYTQG +GTPTAPQLETVFTAIGEMV---- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. 7K507 TaxID=2530365 RepID=A0A4R4UEL8_9ACTN +--AVDKEFRALEKNRQVRIGAYAIDTGDGRAV-GYRAGERFPFLSTFKAVVCGAVLQKAR +RDPGLMDRVIRYKESDLVDHSPVTEKHVKTGMTVAELCRAAIVVSDNTAANLVLKQIGGP +AGDTAFFRSLGDRHSRHDRWEPEANDWKPGEVRDTLVPRGWAHGLRTLTTGNALAPADRT +RLIGWMKATESGADRIRAGLPEGWTAGNKTGTGGYGTANDTAIAWPPSGAPLIIVVTTNR +RAADGTEDPAAIAKAASALVR-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium shinjukuense TaxID=398694 RepID=A0A1X0JUK8_9MYCO +--DLTGHFAELERKYQARLGVYVPASGATAAI-AYRADERFAFCSTFKAPLVAAVLHQFP +--LTHLDKVITYASNDIRSTSPITQQHVDTGMTVGQLCEAAIRYSDGTAANLLLADIGGT +AAFTSYLRGLGDQASRLDQEEPELNRNPPEDHRDTTTPRAIALVFQQLALGDALPPDKRA +MLTDWLARSTTGAKRIRAGFPADWKVIDKTGTGDYGRANDVAVVWSPGGAAQVVAIMSDR +VTYDAQPSEALIAAAATRIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Comamonas testosteroni TaxID=285 RepID=A0A5A7MD29_COMTE +--TLSDELAALEIQARGRFGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ +RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVHELCEAMVLVSDNTAANVLLEASGGP +AALTQWLRELGDSTTRLDRNEPSLNTALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA +LLQQWLVDSRTGDKRVRAGMPGDWKAGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG +SQLDGAGREAVLARAGEAIK--- +>[subseq from] class A beta-lactamase n=4 Tax=Proteobacteria TaxID=1224 RepID=UPI000BA2848C +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAG--------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis taihuensis TaxID=260084 RepID=A0A1G4S2H7_9CAUL +----AQRMIEIQKRHGGRVGVSALNAEANGSL-SIQSNDHFAMCSTFKWVLAAAILQQVD +QGKLNLSDPVRYGKKDLLEYAPTTTANVAKGMTIGELCLAAVSLSDNTAANLLFPLIGGP +AGLTTFVRGPGDTVTRFDRTEPSLNTNIDGDEKDTTTPEAMSTLLRMVFTGSVLKPESLK +SLKDWMVATSTGDARIRAGVPKGAVVADKTGTGANNATNDVGVIWLPNRPPVFLSIYTSG +GSLDADGRNAVIADITRLVFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F59E3F1 +--TAHAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKVAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPSRAPIVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI000E0D0DEE +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACLATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] Beta-lactamase n=1 Tax=Paucibacter sp. KCTC 42545 TaxID=1768242 RepID=A0A0U3EZR1_9BURK +-sELQARLDALQKRSGGRIGLFALNSGSRAQI-AFQADQRFAFCSTFKLLLAAAVLARVD +AGQLNLDKPIRYSSNDMLAHAPITSARLVNGMSVGELCEAIVTVSDNPAANLLFPLVGGP +PGLTRFLRELGDPHTRSDRIEPALNSNQAGDERDTTTPAAFVNSMEALLLGNRLSEEALQ +LLVGWMVGSTTGLQRLRAGLPEGWRAGDKTGTGAGGAVNDVAIAWKPEQAPLLMAVFMSG +SAQSVDELNAIHAELAGLVVK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=A0A1S1KXJ7_MYCCH +-------LASLERDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYAQSDLLEWAPITSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD +LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP +DDPKSTQGKPTIAAATRIALKAf +>[subseq from] class A beta-lactamase n=1 Tax=Lentzea sp. NEAU-D13 TaxID=2714351 RepID=UPI0013FA2BF4 +---LTGKLRELERLHNARLGVFATDTGTGRTV-LHRADELFPMCSTFKTIVAAAILRRDH +-DGTLLGKVIRYTKDDCEKYAKITEKNLANGMTVSALCEATITYSDNCAANLLLKELGGP +TAITRFSRSIGDPVTRLDRWEPELNSAEPGRITDTTSPRAIGQSYARLTLGHALNRADAG +QLTNWLLANTTGDHRIRAGLPAAWRWGDKTGSGKYSTTNDVGIAFPPGRAPIVIAVLSTK +KDPEGGADEPLVAKTAELVAASf +>[subseq from] Beta-lactamase n=2 Tax=Mycobacterium attenuatum TaxID=2341086 RepID=A0A498Q537_9MYCO +--DLQNRFAELEHRYAARLGVYVPATGTTSAI-AYRADERFAFCSTFKALLVAAVLYQYP +--LSHLDKVVTYTSADIRSTSPITEQHAATGMSVGELCDAAIRYSDGTAANLLLAEVGGT +SGFTGYLRGLGDSVSRLDQQEPELNRDPPGDERDTTTAHAIALDYQQVVLGDALPPDKRA +MLTDWMARNTTGAHRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPAGVSHVVAIVSDR +ASYDAEWSEALVADAARCVA--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia sp. NRRL S-836 TaxID=1519492 RepID=A0A0N0A442_9NOCA +-----DRLVALEQKFGARLGVFASR--GDRTV-EHRADERFAFCSTFKGLAAAAVLSRAV +----PLDTVVRYTEAELMKSSQITRRHVATGMTVRELCDAAVRYSDGTAGNLVLRTAGGP +AELTAYLRGLGDEVTRMDRVEPDITSAVPDDPRDTSSPRALGTTYRKLVVGNALPDAHRA +FLRDLMERNTTGGQRIRAGVPKDWKVADKTGTGSYGTVNDIGLAWPPTGEPLLIALMSSK +PAEDAAYDQALLAEAAAYVVT-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QD28_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVVRRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI0004C95922 +----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD +HDGSQLSRVIRYTEADVTKHAPVTKDHIGTGMTVRDLCDATIRYSDNCAANLLLRELGGP +TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA +LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDGAPVLLTALTHK +PSPTAPGDTPLIIKLATV----- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces agglomeratus TaxID=285458 RepID=UPI0008690385 +--RISRRLRDLEREHSARLGVYARNMVTGKTV-AHGADERFPMCSTFKTIAVAAVLRDLD +HDGTFLAKRIHYTAEYAKAYDKITGQNVTNGMTVEELCGAAISYSDNAAANLLLNELRGP +TAVTRFCRSIGDGTTRLDRWEPELNSAEPGRITDTTPPRAIGRTYARLVLGNALAPADRK +RLTGWLLANTTSDEKFRAGFK-GWTVADKTGSGSYGTTNDVGVVWTPKGSPIIVSVLTTK +HEADAAADGALVRRAAELL---- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea gerenzanensis TaxID=93944 RepID=A0A1M4EC41_9ACTN +--TVKKELRALEAAFKGRIGAYAVDTATGRTL-AYRAGERFPMLSTFKAPLCAAVLHRAR +TQPGLMSRHIKWTAADMKPNSPVTEKHVKDGLTVSELCVAAVTQSDGTASNLLMKLIGGP +AGMTAFFRTLKDPISRMDRWHPELNDWTPKDRRDTTTPAAMAADLRALATGTALHAKDRE +QLVAWLLASKVGAERIPAGLPKTWTIAHKTGTNSFGGGNDIAVVWPKRGAPIIMAVYTNR +TP-GLPTDNQTIARTATVLAK-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. Leaf104 TaxID=1736254 RepID=A0A0Q4ZPN3_9RHIZ +--EAEAALARIAGELGGRAGIAVLDTGGGPAL-LHDAEAAFPLCSTFKLLLAAAILARVE +AGRERLDRRLAYGAADLDAYAPVTGGALRAGMSVEALCAAAMVWSDNTAANLLLGALGGP +AALTAWCRDLGDPATRLDRTEPDLNSAVPGDPRDTTRPATMAATVAKILLGPTLTEAGRA +RLEGWMTASRTGTKRLRAGLPASWGVGDKTGTGSNGTANVVALLRPPARAPLVAAVYLTG +SDAPSEARDAAHAAIGRVIAETy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. A1277 TaxID=2563103 RepID=A0A4S2RR44_9ACTN +--SATARLRELERVHGARVGAFAYNVATGVAV-RHRAEERFPMLSTFKTLAAAAVLRDLD +RDGEVLDKVIHYTEADCVSDSPVTGTNIANGLSVARLCDAAIGDSDNTAANLLLRELGGP +GAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPGALARDYARLVLGNVLEPRDRE +RLTEWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYASCNDVGVAWTPEGAPVVLAVLTTK +PGGDAAEGDHLVREAAAAL---- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. YAU14D1_LEIMI4_1 TaxID=2072407 RepID=UPI000D5421C9 +------DFAALEKASGGRLGVTVLDTGSGRRLgGHRQDERFPMCSTFKSMLVAHILSLAD +AGRLSLDTRVPITERDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP +AALTAFLRAQGDRVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGSGLLSPSRL +QFADWLIDNQTGDACLRAGLGPRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG +ARVDEAQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) TaxID=339670 RepID=Q0B8E1_BURCM +--AAQAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPVCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP +QAVTSFAHESGDTVFRLDRWEPELNLAAPGDERDTSTPVAMVDTVQQLLLGDTLREPQRA +QLTEWMTGGTRGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAVRIAT--- +>[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus proomii TaxID=84407 RepID=UPI000985CCCA +-------FRMLEEEYDAKLGIYALDTGTNQIV-SYRAEDRFAYASTHKVLSVGVLLQQND +--INKLEEGILIEEDDLVNYNPITEKHVGEQMTWREISDASIRYSDNAAANHILEQIGGP +EGFKKALRDIGDDVTNPERIEPYLNQVKPGETRDTSTPRALATSLLSFTIGDALTKEKQD +LLVDWLKRNTTGDNLIRAGVPKGWEVGDKSGSASYGTRNDIGIIWPPNEDPIILAVLSSQ +DEEDAEANDELIAKATEKVI--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces coeruleorubidus TaxID=116188 RepID=A0A5J6I7N3_STRC4 +------RLADLEREYGARVGVYALATGTGATA-VHRADERFAFCSVFKALAAAAVLHHRS +--LDGLDRRVTYTRADLKSTTPITGRNVATGMTLRQLCDAAVRHSDGTAGNLLMRDLGGP +AKLTAYLRGLGDTVSRMDHYEPELHDVPPDDPGDTTTPRAVATDFRKLLLGTALPAGERA +LLTDWLSHNATGARRIRAGLPKDWQVADKTGTGNYGRANDIAIVRPPRTEPLVLAVMTDR +PGYDAEPSNALIAEATAR----- +>[subseq from] L2 family class A beta-lactamase n=7 Tax=Bacteria TaxID=2 RepID=A0A6B8HW58_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVVRRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] BlaL family class A beta-lactamase n=1 Tax=Streptomyces sp. NHF165 TaxID=2175864 RepID=UPI00132F1437 +--AHEKEFRALEKKFDATLGVYAIDTADGQEI-THRADERFAYGSTFKALQAGAILRKFS +AEADGMDKVVHYGQDAILPNSPVTEKHVADGMSLRELCDAVVRYSDNTAANLLFDQLSGP +KGLNAVLKQLGDHTTSMDRYEQELGSAVPGDPRDTSTPRAFAEDLRAFAVEDALAPNDRE +QLNDWMSGNATGDALIRAGVPKDWKVEDKSGQVKYGTRNDIAVVRPPGRAPIVVSVMSHG +DTQDAEPHDELVAEAASVVAD-- +>[subseq from] Beta-lactamase n=2 Tax=Tardiphaga sp. OV697 TaxID=2135487 RepID=A0A2U0U8U5_9BRAD +---APTALQAYERDTGGRIGVYAENLKTGAKI-AWRANERFVMCSTFKASLAAFVLARID +RGDDKLEQMISYAAADLLQYAPVARDNLAKGLSVADMCKAIVELSDNTCANMLLARVGGP +AALTAFWNRTGDSISRLDHNEPLLNRSRPGNPQDTTTPAAMAGNVKRFVTGDVLTPASRN +QLTDWMVNCKTGDKRLRAGLPKTWKVGDKTGNNGKDAAGDIAVTWPKPDQPIVIAAYTQG +GAPTAPQFETVFKAIGEMVG--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. A0958 TaxID=2563101 RepID=A0A4S2TSB2_9ACTN +--STSARLRELERAHGARVGAFAYNAATGVAV-RHRADERFPLLSTFKTFAAAAVLRDLD +REGEVLDKVIHYTEADCVSDSPVTGTNIANGLSVARLCDAAIGDSDNTAGNLLLRELGGP +GAVTRFARSLGDRVTRLDRWEPELNSAEPGRITDTTSPASIARDYARLVLGSALEPRDRE +RLTEWLLNCRTSGTRFRAGLPPEWTVADKTGGGPYGSCNDVGIAWTPEGAPVVLAVLTTK +PGPDAAGDHPLIREAAGMLA--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia brasiliensis TaxID=37326 RepID=A0A379BXU4_9NOCA +----HDRLFELERKFDARLGVYALDTASGATI-AHRADERFAFCSTFKGLAAAAMLHRNP +--MSHLDTVIRYTDEDLTKNAAITPQHVATGMTIRDLCDAAVRYSDGTAGNLLLRDIGGP +AELTAYLHGLGDPVTRMDRIEPAITEATPGDLRDTSSPRALSTDYQRIVLGDALPGGKRA +FLRDLLERNATGAGRVRAGVPPGWQVADKTGTGDYGTLNDIAIVWPPERAPLVISLMSSK +ATAAAEYDQALLAEAAAYVVK-- +>[subseq from] Beta-lactamase n=2 Tax=Tardiphaga sp. OK245 TaxID=1855306 RepID=A0A1H6NH51_9BRAD +---APAALQAYERDTGGRIGVYAENLKTGAKI-AWRANERFVMCSTFKASLAACVLARID +RGEDKPDQMISYAAADLLDYAPVARDNLAKGLSVADMCKAIVELSDNTCANMLLARVGGP +AALTAFWNRTGDSVSRLDHNEPLLNRSRPGNPQDTTTPTAMAGNVKRFVTGNVLTAASRD +QLTDWMVNCKTGDKRLRAGLPKSWKIGDKTGNNGKDAAGDIAVTWPKPDQPVVIAAYTQG +GTPTAPQLETVFTAIGEMV---- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3S9NKD9_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCAAMLQAGDKGAGNLLMGVLGGP +QAVTAFAHESGDTTFRLDHWEPELNRAVPADERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PDAAAAARADVVASAARLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium aphoticum TaxID=754436 RepID=UPI000B262FEA +---VQTQIQAIEQTLSAHIGVAVLDTQNNTRW-SYKGDERTPLTSTFKTLACAKLLHDAE +NNTLALIDTVTIKASELVTYSPVTEKWVGKAIPVVQACEATMFTSDNTAANIVIHAVGGP +DKITAFLRQSGDAVTQLDRFEPALNEATLGDVRDTTTPNAMTQTLNTLLFKNGLSKQNQQ +QLIDWMVGNQVTGNLLRSVLPQGWTIADRSGAGGHGARSITAVVWPEDRAPVIIAIYVMQ +TEASFDARNQAIVTIGQAIFNLy +>[subseq from] Class A beta-lactamase n=1 Tax=Pantoea alhagi TaxID=1891675 RepID=A0A1W6B9K6_9GAMM +--TLTQKLAGLEKASGGRLGVAWID--GDRRY-GYRANERFPLTSTFKALAVSAILHKSV +SQPGLLEKKVMINNADNVPWTPVTGNYIGKAMSIGALCAATIEYSDNLAANYLLHELGGP +QGVTAWARQLGDRITRLDRYEPDLNSAVPGNQRDTSTPAAMASNLNQLALGDILPVKQRQ +MFNRWLKQNTTGDESIRAGVPEGWVVGDKTGAGEYGTTNDLAVLWPDKAQPKILAIYFTQ +PQRKAASNKAVLAAATRAVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces laurentii TaxID=39478 RepID=A0A160P6W0_STRLU +-------FGELERAYDVRLGVYALNTGTGATV-VHRPAERFAFCSTFKTLVVAAVLRADS +--PIHLDKRVRYGWSDIDSVSPVTREYVAEEMTIRQLCDAALRYSDGTAANLLLRELGGP +DRLNAWLRGLGDTVSRLDHDEPELNRMRPGDPADTTTPQAIAADYRRIVLGDALSDDRRA +LLTDWMERKANGGNPIRACLPRGWRIADRTGAGDYGRTHDIAVVWPPRSAPLVLAVMSER +SRRADSPREAVLTEATRHIT--- +>[subseq from] class A beta-lactamase n=1 Tax=Tatumella sp. TA1 TaxID=2487345 RepID=UPI0008F8B4B7 +-eNISAQLAQLEASVPGRLGVYLIDPIHNDSY-SYKGDERFPFCSTGKVLVVAKLLHDSQ +TNPLTMNIAMTIQQNDLTNYNPITGQNVGKRMTVSTLSQAALQYSDNTAMNLLLRQAGSI +GAINAFARTLGDRLFLLTRNEPSLNTSLPGDERDTSTPYAMAHTLQKLTLGNGLEKDKRD +LLTQWMKGNTTGNASIKAGVPTNWTVADKTGSGDYGTTNDVAVMWTEKHNPIILVVYFTQ +FQQDALPRKDVLAKAANIVTS-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodovulum viride TaxID=1231134 RepID=UPI000DC3AFCE +--ALADTIARLETALPARIGVAIRDSGSDWGW-SHRDSERFLMASTFKSVLCGAVLDRAD +RGLLSLGDAVAIPPEAILDYAPVAETHVGGTMTLGDLCLAALDMSDNTAANLLIDRLGGP +QEVTAFLRRIGDPVTRLDRTEPGLNLFDPADPRDTTSPAAMAATWQRLLLGDVLSPASRA +RLADWMSHGSVTASLIRASTPPDWTVSDKSGGGRDYTRNLVAMIQAPGRAPVIVAIYLSD +CPADWATRNAAVAEIGAAVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia acaciae TaxID=551276 RepID=UPI0012EEC317 +-------FSSLERKYSVRLGVYAVDTGSGAFL-EYRADERFAFCSTFKTIAVAAVLWQRP +--LSYLDTVVRYTKADVNSISPIADKHVDTGMTVGQLCDAAIRYSDGTAGNLLMRDIGGP +AQLTAYLRGLGDPTSRMDQYEPDLNSDPPGDPRDTSTPRALAGDHRAIVLGNALPPEKQS +LVKDWLRRSATGAQTIRAGVPAGWTVAGKTGHGDYGRANDVAVVWPPNGAPLVIAVMSDR +AGFSDEPRYPVIADVAAHVT--- +>[subseq from] Beta-lactamase n=1 Tax=Desulfovibrio desulfuricans TaxID=876 RepID=Q8KVT3_DESDE +-kTLQKKLAELEAASGGRLGVAARSSNGGKSL-SYRGDERFPMCSTFKVLAVAALLRDKP +---GILEQRIHFAQIDIQPWSPVTEKHLEDGMTVAELCAAMLQHSDNTAANLVLAKLGGP +QGLTSLARSFGDTTFRLDRWEVELNTAIPGDARDTTTPLAMCNTLNGLLCGNLLKAPARE +RLTGWMLGCATGAGRIPAGIPQGWRSAHKSGSGENGTANDVGVLLPPKGKPLTVALYLTG +SRLTGPENDKILASATRLVC--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=A0A3P0CLY0_9BURK +----RAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGA +LDASLLPRRILYRRYEIVSGSPITESRVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PEATAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=2 Tax=Salmonella enterica TaxID=28901 RepID=A2TJ36_SALTM +-qQVEQDVKAIEVSLSARIGVSVYDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGHSIFDVy +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0011550EEB +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAC--------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia terrae TaxID=311230 RepID=A0A2I8ELI3_9BURK +---ARERFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM +AERSLLDERVRYGDADLVANSPVTKRHVGEGMTIGELSAAALQHSDNTAAKLLLTAVGGP +EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE +QLKAWMLGNVTGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVVAVYFTG +VMKQTLPRDEVVVEAARIVFD-- +>[subseq from] Beta-lactamase n=3 Tax=Vibrio TaxID=662 RepID=A0A5C9Q9M4_VIBCL +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVTWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI000A0F58F5 +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVTWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] Beta-lactamase n=1 Tax=Lentzea waywayandensis TaxID=84724 RepID=A0A1I6D0Z3_9PSEU +--TVTGKLRELEKQHNARLGVFATDTGSGRTV-LHRADELFPMCSTFKTIAAAAILRKDR +-DGTLLNKVITYTKSDVDKYGPITGRNLANGMTVSALCEATITYSDNCAANLLLKELGGP +TAISRFSRSIGDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGQSYARLTLGHALNSNDSD +QLVKWLLANTTGGNRVRAGLPAAWGWGDKTGTGKYSTTNDVGIAFPPGRAPIVIAVLSTK +KDPEGGADEPLVARTAELVAAQf +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis thermalba TaxID=944492 RepID=UPI000E235A54 +-----VSFADLESRFDSRLGVYAIDTGTGREI-AHRADERFNYASAIKSLLAGAVLRRNV +----DLDKVVTYTDADIQPNSPITKDR--RSVTVCEAAEAALLQSDNTAANLLFAEVGGP +AGLAAVLREIGDTTTHPDRLEVELNSAIPGDIRDTSTPRAMAGSLRAFLLGDALPADKRD +LLVGIMRRNRTGAELIRAGVPSEWPVADKTGTGDYGTRNDIGVIWPPTGAPVVLALMSSR +GTPDAEHDNKLLAEAASRVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Alteromonadaceae bacterium M269 TaxID=2546219 RepID=A0A4V2ZG83_9ALTE +---LAKMLDALEEQYGGSFGLSILDVETQKQF-SINGDMRFPMMSTFKSLACAKLLHDAE +NGKQSLKATHLIQKQDIVTYSPVMKKKVGDEIALIDACAVTMKTSDNAAANIVLSETGGP +ADLTSFMRAMGDKITRLDRYETELNSAIAGDERDTSTPNAMTKAYYQLLYGDVLSEASES +QLTDWLKSNEVGGSLLRSVLPNGWSIGDRTGAGENGSRGIVAVVWPQDRSPFIVAIYMTQ +TSASFKERNQAIADIGRVIF--- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces yanglinensis TaxID=310779 RepID=A0A1H6D5E7_9ACTN +----SRSLAALESRFHAHVGLFALDTGSGRTV-AYQADRRFAHCSTVKVLAAAVLLKRES +--DAGLDRVITYPSSDLVTYSPVTSKHAGTVMPLRDVIDAALRYSDNTAENLMLDQLGGP +PGLQKAVHALGDTTTRVDRPEPALNDATPGDVRDTSTAGALGADLRRLLLGDVLPAERRS +LLVDLMVRNTTGGPYVRAGVPAGWKVADKTGSGGYGTRNDIAVAWPPHGSPVVISVLTDR +GATDAASADALVADATKAALT-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces gancidicus BKS 13-15 TaxID=1284664 RepID=M3DA14_9ACTN +---------------------FAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDRRP +--GARLDERVSYSTADLVTYSPVTEKHTADGMTLRQLCDAAVRYSDNTAGNLLLRDIGGP +RGLTAYARRLGDRVTRLDHVEPELNSNPPGDPRDTTSPRAIAADYRALVLGDALPAAGRA +LITDWLVRNTTGDRRIRAAVPRGWRVGDKTGGGEWGRGNDVAVLWPGGRPPLVLSVLTER +TDRAASPSDELVAEAARRVLD-- +>[subseq from] Beta-lactamase (Fragment) n=11 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A2L1J0Y1_ECOLX +---------RLERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDI------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. P16(2019) TaxID=2597270 RepID=A0A553ZWU7_9BACI +--SLEEQLSKLEEEYDARLGIYAFEAGGETAV-AYQEDERFAYASTHKALAVGVLLQQKT +--MEELEKRITYTEEDLVTYSPITEQHIDTGLTLKEISDASIRYSDNSAANFIFDEIGGP +EGFAQSLREIGDDVTQPERIETELNDVKPGETRDTSTAKALAESLYTFSVGDGLEEEKRE +LLNDWLIRNTTGDHLIRAGVPEEWKVGDKTGSAAYGTRNDIGVIWPPDSEPIIIAVLSSR +DQEEADTDDELIAKATEEVIKRf +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. 9128 TaxID=1793722 RepID=UPI0011A8ED72 +---SNQAFAALEREHDARLGVTAIDTGSGHRV-TYRQDERFPFASTNKTFIAAAVLAHDS +--DADLDTVVHYDRSDLLAYAPVTSRFVATGMTVRELIDAAMRFSDNTAANLLVERVGGP +AAVEQWLRGIGDRVTNVDRTEPDLNQATPGDERDTTTPAQFASDLRSVILGSTLGATDRT +FLRDTMLDNTTGAATVRAGVDSAWPVADKTGTGEYGVRNDIAAVYPAGRAPVIVVVMTAT +DRSGATADDALVAAATKQAV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Nafp2/4-1b TaxID=2116686 RepID=A0A495YSH1_9BURK +--AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVTAAAILARGS +LDASLLPRRILYRRYDVVAGSPVTENHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTVFRLDHWEPELNRVAPGDERDTSTPVAMVDQLQRLLLGDTLREPQRA +QLTEWMTGGARGATGIAAGVPPGWRIADKAGSGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PSADAAARADVVASAARIATGAf +>[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea coxensis TaxID=404386 RepID=UPI00037278E2 +--QVTKELRALEKSYKGRIGAYAIDTATGRTV-GYRSGERFPLLSTFKAPVCAAALHKAS +TSPGLMDKVVKWTKADLKPHSPTTEKHVEDGLTVAQLCEATITLSDNTAGNMVLKQVGGP +AGLTRYFRSLKDPVSRLDRWETELNDWTAKERRDTTTPAAISRDLRLLTWGDALNAQDRR +RLNGWLRANQTGDARIRAGLPKSWTIGDKTGTNEIGGANDIAVIWPDKGAPIIMAVYTTR +STPS--VDDKVLAKTATVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus saganii TaxID=2303992 RepID=A0A372LRF0_9BACI +----MEKFEQLEKQYDARLGVYAIDTGTKETV-AFREDERFAYTSTSKALAAAVLLKQNP +--ISVLEEIRTFTNEDIVTYSPITEAFVNKGMSLGKIAEAAMQFSDNTAGNLLFEELGGP +DGFEKALRESGDTITMADRIEPDLNEAIPGDSRDTSTPKALAINLEVFGISEYLPADKQE +IFTHWLKGNTTGDSLIRAGVPEGWEVGDKSGAGGYGTRNDIGIVWPPNREPIIIAIMSSR +NEENASFNDELIAKATKVITQAf +>[subseq from] Beta-lactamase n=1 Tax=Halomonas halmophila TaxID=252 RepID=A0A4Y4EWV4_9GAMM +-tDLKQRLAELERAEGDRVGVALMNVATGAVA-SHRGDERFLFNSTGKFFIAAAVLARVD +EGSETLDRRIAIEEGDLVGWTPITEKRLGEPLTIAELCQAAVAWSDNAAANALTESVGGP +AAVTAFLRSIGDDTTRMDRVEPDLNTDHEGDERDTTTPLAMMTTLRTLMLGDALTPSSRH +QLASWMIEGKVGDARLRAGMPSSWLVGEKTGTNGEGNASDIGIAWPGDRGAVIAVAYTLM +PGATGEQRDETIAAVGRLAAD-- +>[subseq from] Beta-lactamase n=1 Tax=Comamonas thiooxydans TaxID=363952 RepID=A0A5D9AKU1_9BURK +--TLSDELAALEIQAQGRFGLYVLDAVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ +RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVLVSDNTAANVLLEASGGP +AALTQWLRELGDGTTRLDRNEPSLNTALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA +LLQQWLVDSRTGDKRVRAGMPGDWTVGGKTGSGERGTACDTLIVWPTEQAPLLVTAYLTG +SPLDGAGREAVLARAGEAIK--- +>[subseq from] Beta-lactamase n=2 Tax=Rubidibacter TaxID=582491 RepID=U5DGZ8_9CHRO +--DLIATVRQIEAALDARVGIAVYDKETDRNW-QYHADERFPMNSTFKTIACAALLSLVD +SAQEKLDRIVVFDESDLVDYSPITETRFGPPMTLDELCEATMSVSDNSAGNFVMEAIGGP +EAITQFMRSIGDEVSRLDRWYPSISESVPGDKRDTTSPNSMAMMLEQLVLKQTLSLGSRQ +KLENWLKGNEVSDNLFRAVIPSDWDIGDRSGAGQYGSRSIAAIMWPPQREPVVAAVYITE +TEASFAERNAAISEIGEEIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia seminalis TaxID=488731 RepID=UPI000F5A9D3B +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEVVSGSPITESRVDTGMTIAQLCEAMLQAGDKGAGNLLMGVLGGP +QAVTSFARESGDTTFRLDHWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLHEPQRT +QLTEWMAGGARGATGIAAGVPPGWRVADKAGTGGYGTMTDVAVLWPPSRAPIVMAVSFTQ +QQADAAARADVVASAARIAA--- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI00115BB202 +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACLATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGLGARSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] Beta-lactamase class A n=1 Tax=Alloactinosynnema iranicum TaxID=1271860 RepID=A0A1G6XQ11_9PSEU +----HTALAELERKYSARLGVYAIDTATNTTI-THHPDDRFAFCSAFKALAAAAVLHRNP +--LSHLDTTVQYTRTDLMKHSPITARHVATGMTIRQLCDAAIRFSDGTAGNLLLRDLGGP +ARLTDYARGLGDTVTRMDRTEPDITEATPGDPRDTSSPRAFGSTYHRILLGDALPTDKRD +FLRDLLDRGVAGADRIRAGVPKEWAVAHKSGTGDYGTLNDFAVVRPPNAAPLVVSIMSSK +ADRDADSDPALLAETAAYVVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia TaxID=32008 RepID=UPI000B79F8F2 +----QAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGA +LDASLLPRRILYRRYEIVSGSPITESRVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSHAPIVMAVSFTQ +PEATAAARADVVASAARIAA--- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI000E0A01F5 +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACLATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ +TETSMAERNDAIVKIGRSIFEVy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3Q9X1Z2_ECOLX +--------KQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGI-------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID5785 TaxID=2690309 RepID=UPI001361D4DA +--HLTAELGALEEQYAARLGVYAHDLGTGRTV-RYRAGERFPLCSVFKGIAAAAVLRDLD +HDGSELAKRVHYTQAEVDRYAPVTGEHVAGGLTVAELCAAAVGESDNAAANLLLRELGGP +TAVTRFCRSTGDRVTRLDRWEPELNSAEPWRRTDTTSPQAIGTTYGRLVAGRVLAPDDRA +RLTGWLVANTTNTERFRAGLPADWVLADKTGGGSYGVANDVGVVRPPGRAPIVLSVLSTT +HAAEGPSQSALVARAAGLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium attenuatum TaxID=2341086 RepID=UPI000F0398A1 +--DLQNRFAELEHRYAARLGVYVPATGTTSAI-AYRADERFAFCSTFKALLVAAVLYQYP +--LSHLDKVVTYTSTDIRSTSPITEQHAATGMSVGELCDAAIRYSDGTAANLLLAEVGGT +SGFTGYLRGLGDSVSRLDQQEPELNRDPPGDERDTTTAHAIALDYQQVVLGDALPPDKRA +MLTDWMARNTTGAHRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPAGVSHVVAIVSDR +ASYDAEWSEALVADAARCVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A103RPK5_9BURK +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA +LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPGRA +QLTKWLLGSANGVAGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADASPRADVIAEAARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=A0A1S1M2E7_MYCCH +-----SELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIRYAQSDLLEWAPVTSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEDQLN--VPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD +LLTDWLKRNTTGDQSIRAGVPTAWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP +DDPKSTQGKPTIAAATRIALKAf +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium aquaticum TaxID=1927124 RepID=A0A1W9ZY20_9MYCO +---LDDQIAGLEKRNNALIGVFAANLDSDRTV-AHRADETFAVCSTFKGYAAGRVLQQVD +RGQLALDTRIFIDPNAIVANSPVTEERTGADMTIGELCQAAVQHSDNTAGNLLLKMIDGP +PGITAFARSIGDNRTRLDRWETALNSAIPGDPRDTSTPAALGAGYRAMLTADVLSPPQRQ +QLEDWMRGNET--SSLRAGLPAGWTSADKTGSGDYGSTNDVGIAYGPDGQRLLLAMMTRS +RADDPKA---------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3G4SNC1_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFTLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGR----------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D61AE +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANSVKGIRAGVPSDWRVAGKAGTGGYGTMTDVAVLWPPSHAPLVIAASFTQ +PGADAPPRADVIAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium iranicum TaxID=912594 RepID=UPI000464F327 +---VEERIEALANRHNAQIGLYAVNLDSEESL-GYRDTEVFAMCSTFKAYAAAAVLQRAQ +QGRLALRDTVPIEAADIRPHSPVTEPRVGTAMTLAELCQAALQQSDNAAANGLLRALGGP +PAITEFARSIGDDRSRLDRWEVELNSAIPGDPRDTSTPRALGAGYRAILTGDVLQPAGRQ +QLVDWMLGNQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVVYGPSGQRMLLAFMTRS +AVPDAASLRPLIGELATLVMA-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces pristinaespiralis TaxID=38300 RepID=B5HBK2_STRE2 +----HDRLVELERKYDARLGMYALATGSGKVI-AHRADERFAFCSTFKGLAAAAVLDRNP +--LSHLDTLVRYTEADLLKNASITPRHVSTGMTIRGLCDAAVRHSDGTAGNLLLRDLGGP +AELTAYVRGLGDTVTRMDRIEPLITEATPGDPRDTTSPRAFGSDYREIVLGDALPPEKRA +FLRDLLERNATGAARVRAGVPKGWAVADKTGTGSYGTLNDIAVVWPPGSAPIVISIMSSK +ATEDAAYDQALIAEAAAYAV--- +>[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. Arc7-R13 TaxID=2500532 RepID=A0A3T0PX78_9RHOB +-----EAARAVEAELGGRVGVALRRQGSPEGE-GYRAGERFPLSSTFKAPLCGAILTLVD +AGEDQLDRVIGYTSGDLVTHSPVTETR--DAMSVADLCEATLTLSDNTAANLLLERVGGP +EGFTDYLRAIGDETTRLDRWETDLNEGAPGDPRDSSTPEAMIATLERLLFGPVLSEPSQQ +QLEAWMRANAVADDLIRASLPEGWTIADRTGAGGYGSRSIVALIRTPQDEPWLAAVYLTG +NAADMASRNAAIARIGQAIVT-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9031 TaxID=2184566 RepID=A0A3P0NJV1_9BURK +--AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAVLQAGDKGAGNLLMGVLGGP +QAVTSFAHESGDTAFRLDRWEPELNQAAPGDVRDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMTGAR-GATGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIAT--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=UPI00071674FB +--AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAVLQAGDKGAGNLLMGVLGGP +QAVTSFAHESGDTAFRLDRWEPELNQAAPGDVRDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMTGAR-GATGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIAT--- +>[subseq from] Class A beta-lactamase n=1 Tax=Salipaludibacillus neizhouensis TaxID=885475 RepID=A0A3A9KJF8_9BACI +----MEKFEQLEKEYDARLGVYAIDTGSKETV-EFCEDERFAYTSTSKALATAVLLKQNP +--ISVLKEIRTFTNEDIVTYSPITEDFVNKGMSLGKIAEAAMQYSDNTAGNLLFEELGGP +DGFEKALRESGDTITMVDRIEPDLNEAIPGDSRDTSTPKALATTLEVFGISEYLPTDKQE +IFTNWLKGNTTGDSLIRAGVPEGWEVGDKSGAGGYGTRNDIAIVWPPNREPIIIAIMSSR +DEENASFNDELIAKATKVIAQAf +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI0007EC2294 +---IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYAAARVLQMAE +HGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPGGQRLLLVMMTRS +QAHDP-KAEN------------- +>[subseq from] Beta-lactamase n=1 Tax=Cryobacterium sp. SO1 TaxID=1897061 RepID=A0A4Q7D7H4_9MICO +-----AEFTSLEATYDARLGVYALDTGTGSEV-SWRDDERFAYASTIKAMAAAALLDTVG +--LAGLATPVPIEESDIVPYSPVTEPRVGGSMTLGEIAHAAMTVSDNTAANLMFEALDGP +AALDADLSGLGDDTTVVSRTEPDLNEAVPGDDRDTTTPRAFATNLNAYLFGEQLSGEEKA +QLETWLTGTQTGDTLVRADLPADWVVGDKSGSGGYGTRNDLALIRPPGRAPIIISVMSSK +AEPDAESDDKLIAEAAAAAM--- +>[subseq from] Beta-lactamase n=1 Tax=Endozoicomonas elysicola TaxID=305900 RepID=A0A081KB33_9GAMM +-------ARDLENRHGGHIGIAVMDTSNQSLW-DYRGNTRFPLMSTFKTLACAKLLADAD +QKKQKLTTEAMITRESLVTYSPVTEPLTGQRITLEQACDATMTTSDNTAANLVLTGIGGP +QQLTDFLRSTGDTVTRLDRIEPELNEAKQGDLRDSTTPLAMADTLNQLILGNTLSDGSRA +QLKTWMMGNQVADNLLRSVLPEGWSIADRSGAGGHGSRGITAIIWSEKRLPLIISIYMTG +TNASFEERNQIIVKTGEAVFNHf +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium septicum TaxID=98668 RepID=UPI00040E3028 +---VDDQIAELERRDNVLIGLYAANLDSGRIL-THRPDEMFAMCSTFKGYAAARVLQMVG +RRQISLDNRMFVDPEAIVPNSPVTETHAGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAVLAGDALSPPQRR +QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPNGQRLLLAVMSRS +QADDADNLRPLIGELTALV---- +>[subseq from] Beta-lactamase n=1 Tax=Tardiphaga robiniae TaxID=943830 RepID=A0A163YVQ1_9BRAD +---APAALQAYERDTGGRIGVYAENLKTGAKI-AWRANERFVMCSTFKASLAACVLARID +RGEDKPDQMISYAAADLLDYAPVARDNLAKGLSVADMCKAIVELSDNTCANMLLARVGGP +AALTAFWNRTGDSVSRLDHNEPLLNRSRPGNPQDTTTPAAMAGNVKRFVTGDVLTSASRN +QLTDWMVNCKTGDKRLRAGLPKTWKIGDKTGNNGKDAAGDIAVTWPKPDQPVVIAAYTQG +GAPTAPQFETVFKAIGEMV---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter sp. ND5 TaxID=1089784 RepID=G5CK56_9GAMM +--ETLVKVKDAEYQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNGAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRG--------------------- +----------------------- +>[subseq from] Beta-lactamase n=3 Tax=Comamonas TaxID=283 RepID=D0J7U6_COMT2 +--TLSDELAALEIQAQGRFGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ +RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVLVSDNTAANVLLEASGGP +AALTQWLRELGDGITRLDRNEPSLNTALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA +LLQQWLVDSRTGDKRVRAGMPGDWTVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG +SPLDGAGREAVLARAGEAIK--- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter junii TaxID=40215 RepID=A0A059WHE0_ACIJU +-qQVEQDVXAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGHSIFDVy +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. MSMB1835 TaxID=1637876 RepID=A0A104C2B1_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNRATPGDERDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGNGGFGTTTDVAVLWPPSRAPIVMAVSFTQ +PEAAAAARADVVATAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI0007EBC185 +---IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYAAARVLQMAE +HGEISLENRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGEALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS +QAHDAENLRPLIGELTALV---- +>[subseq from] class A beta-lactamase n=1 Tax=Nitratireductor aquibiodomus TaxID=204799 RepID=UPI000814125F +--TLSQTVERIESTLGARVGIMIRDTGSGWRW-SHRAEERFLMNSTVKALICGGVLAKAD +AGALALEDALPIRQFDIVSYSPVTQKQVGKAMSIADLCLATLDMSDNAAANLLIGRLGGP +KAVTAFLRSIGDPVSRLDRLEPKLNAFAPGDPRDTTTPAAMTETWHALLLGDVLKPASRT +QLIEWMSHGGVTGALMRASLPKDWAISDKSGAGSH-TRNLVAMVTPPGRAPFLVSIFISD +TDVDFETRNGALKDVSAAIVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Burkholderia sp. CF099 TaxID=1882791 RepID=A0A658UPW4_9BURK +---ARERFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM +AERSLLDERVRYGDADLVANSPVTKRRTGEGMTIGELSAAALQHSDNTAANLLLTAVGGP +EVLNQFALSIGDEWFDLLRGEPEVNVSVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE +QLKAWMLGNATGAARIRAAVPSGWLVADTTGSGDYGTANDVAVVYPPSAAPFVIAIYFTG +VTKQTPPRDEVVAEAARIVFD-- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio TaxID=662 RepID=UPI000DE29C10 +-qSVEQEIKGMESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACLATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Bradyrhizobium TaxID=2631580 RepID=UPI00110D3A9D +-----PALAAYERETGGRIGVHAENLSTGAKM-AWRAEERFVMCSTFKASLAAFVLARVD +HGADRLADLVAYGPKDLLEYAPVAKQNLAQGMSVSEMCKAIVELSDNTCANLLLARVGGP +AALTAFWRSTGDTISRLDHNEPELNRSPPGNPHDTTTPSAMAGNLRRFLLGAVLTPASRQ +LLTEWMVGCKTGNNRLRGGLPADWKVGDKTGNNGKDASGDIAIAWPKSGGPVLVCAYTQG +GSPAPQQLEAVFKEIGAMV---- +>[subseq from] Class A beta-lactamase n=2 Tax=Mycobacteroides TaxID=670516 RepID=A0A0R3FQ56_9MYCO +-----SELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIRYAQSDLMEWAPITSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEDQLN--VPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD +LLTDWLKRNTTGDQSIRAGVPTAWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP +DDPKSTQGKPTIAAATRIALKAf +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A124L2B9_9BURK +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA +LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLSEAMLQFGDKSAANLLMSVLGGP +QTVTEFARASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPGRA +QLTKWLLGSANGVAGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVIAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycoplana dimorpha TaxID=28320 RepID=A0A2T5B5S1_MYCDI +-------ARKAETGLRARVGLAVVDTASGKTW-LHNADQRFPLASTFKALACAALLD--- +AGADTLNKMAAIGQGELVSHSPVTKAMTGREVPAAGLCAITLRTSDNTAANKVLEVLGGP +AAVTAFLRSVGDDTTRLDRMEPELNEGRPGDPRDTTTPAAMAATLRKLVLGDALGEPERR +QLTDWLVANEVSGSLLRSGIPKDWRIADRSGAGGFGTRGIVAVMWPPHRKPIVAAIYLTE +TGVSMEARNAAIAEIGRAIAAEf +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=A0A2S9NV33_9BURK +--AAQAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPVCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP +QAVTSFAHESGDTVFRLDRWEPELNLAAPGDERDTSTPVAMVDMVQQLLLGDTLREPQRA +QLTEWMSGGTRGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAVRIAT--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000259B766 +-----ADFAALEKASGGRLGVTVLNIGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonadaceae bacterium SCN 69-123 TaxID=1660170 RepID=A0A1E4KZV2_9GAMM +-----AGFAALEAESGGRLGVCLWHPASGARF-GQRMDERFPMCSTFKFLLAAAVLERAG +RGALSLDQRVPVRAADLLAHSPVSARHVGKDLGVRDLCRATLTTSDNAAANLLLPLVGGP +AGLTAFLRAQGDAVTLAARYEPDANRFAADDPRDTTSPAAMAGNLQRFVLGDALALAARR +QLADWLIDNETGDARLRAGLPPGWRVGDKTGSNGRDTSNDIAVLWPRGGTPWVLAAFLQG +STLDDAGRDGILRRVGERAAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=UPI000992BE8E +-----SELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIRYAQSDLLEWAPVTSQHVTEGMTVSELCDATLRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEDQLN--VPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD +LLTDWLKRNTTGDQSIRAGVPTAWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP +DDPKSTQGKPTIAAATRIALKAf +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A2S8IHV7_BURCE +--AAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAGAILARGA +LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIAQLCDAMLRSGDKGAGNLLMGVLGGP +QAVTSFARESGDTTFRLDHWEPELNKAVPDDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPLVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. Leaf111 TaxID=1736257 RepID=A0A0S9NZJ1_9RHIZ +----GAALARIAGDLGGRAGIAVLDTGGGPAL-LHDAEGAFPLCSTFKLLLAAAILARVE +AGRERLDRRLAYGEADLDTYAPVTTRALRAGMSVEALCAAALVWSDNTAANLLLAALGGP +AALTAYGRDLGDPVTRLDRTEPDLNAAVPGDPRDTTRPAAMAATVGKILLGPSLTEASRA +RLEGWMTASRTGTKRLRAGLPADWGVGDKTGSGAYGTANVVALLRPPARAPLVAAIYLTG +SDTTSEARDAAHAAIGRVIAATy +>[subseq from] class A beta-lactamase n=1 Tax=Jiangella muralis TaxID=702383 RepID=UPI00069D691C +----DPAVRELERAYDVTLGVSATNLATGARL-AHRPGDRFPILSVFKSIAAAAVLRDLD +--VSRLEHRVWYPPADIVPNSLITAEHVDTGMTVAELCDAAIRYSDNAAGNLLLRELGGP +RGLTAFARSIGDDATRLDRWEIELNSAEPGDVRDTSTPAALARTFAGLLVGDLLRSGDRR +RLRDWMLANTTSGPRFRDVLPDGWRLADKTGAGDYGSNNDAGVAWNPAGQPIVMVAMSRR +AERDAPRVDAALADVARLVVR-- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio metoecus TaxID=1481663 RepID=UPI00130251E4 +-qSVEQEIKGIKSSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGSGARSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia azotifigens TaxID=2057004 RepID=A0A5C6VUU6_9BURK +---AHERFGQLEASSGGRLGVAAVRTSDGAYV-SYRESERFPMCSTFKLLAVGALLKRSA +AERDLLDTRVRYGPADLVANSPITKQHAGEGMSVGELCAAALQYSDNTAANLLLNVIGGT +EVLNEFARSIGDTWFDLARREPDLNASVPGDMRDTTAPRAMMQDAQKLLLDDVLEAPQRE +RLKAWMLGNTTGAGRIRAAVRTGWPVADKTGSGDYGTANDVGVVYSPATA-YVLAIYFTG +VTKETPPQDAIVDEAARIVFD-- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI00115C2252 +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ +TETSMAERNDAIVKIGRSIFEVy +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI0004C22D79 +----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD +HDGSQLARVIRYTEADVTKHAPVTKDHIDTGMTIRDLCDATIRYSDNCAANLLLRELGGP +TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA +LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDGAPVLLTALTHK +PSPTAPGDTPLIVKLATV----- +>[subseq from] Beta-lactamase n=2 Tax=Tistrella mobilis TaxID=171437 RepID=I3TTT5_TISMK +--RLADTVSRIEDQLDARIGLVLHDTGRGWRW-GHRADERFLMNSTVKMPICGAILAGVD +AGTVSLDETLPIRRADLVSHAPVTKPRVGTAMSIAGLCFATLDQSDNPAANLLITRLGGP +AAVTQFFRSIGDPVSRLDRLEPGLNSAPAGDPRDTTTPAAMAATMETLLLGTGLTPASRA +QLTEWMRHGGVTGALLRRSAPADWQIADKSGAGDT-TRNLVALITPPGRAPWIATIYLGD +AETDFATRNKALAEIGAAVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium tuberculosis str. Haarlem/NITR202 TaxID=1304279 RepID=R4M3D8_MYCTX +--DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAXXXHQNP +--XXHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP +AAFTGXLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGXPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI0007EC63F6 +---IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYAAARVLQMAE +HGEISLDNRVFVDADALVPNSPVTETSAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS +QAHDP-KAEN------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SCF1_KLEPN +-----------------------MDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVV----- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=UPI000C9AE13F +--DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD +RSTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP +EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTASPRSVLSTLHAALSGTMLSGSSSA +QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE +TNADFSRRNQAISDIGRAMI--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1W5MZV2_9BACT +------------LQVDGGLGVSVLDTETGRAS-GWDETSTYPLNSTFKLLLAGAVLQRVD +RGQERLDRQIAVRSSDIVAWSPVAKEAVGGSMSLRSLCEAAMTRSDNAATNLLLRSVGGP +EALTATLRNMGDPVTRIDRYETEMNDVPPGDLRDSSTPSQMLKTMETLLLGDILSARSKE +QLAAWMIANTTGGARIRAGVPSGWTVGDRTGTGPRGETATIAAIYPPNRKPLLMTVYIRG +SSRNRDAQESTHAELARIAT--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium confluentis TaxID=28047 RepID=A0A1X1SH29_9MYCO +----DAALAALEQRYDALVGLFALDLDSGRSL-ARRDDDPFAMCSTFKTYAAGSVLQRAQ +RNELRLDQQVFVDPAELVANSPVTEANAGSSMTLAALCVAALQRSDNTAANLLLQTIGGP +PAITEFARSIGDNRSRLDRWETELNSALPGDPRDTSSPRALGGGYRALLTGDVLDETHRA +QLETWMRGNTTSEKSLRAGLPPGWTSADKTGAGDYGSTNAVGIAFAPDGRRLLLSVMTRS +RSPDAPWLQPLIAEVTALAVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. DL440 TaxID=2675523 RepID=UPI0014227D83 +---IDDQIAELERRDNALIGLYAANLDSGQTL-THRPDEMFAMCSTFKGYAAARVLQLVG +RGQLSLDNLVFVDPEAIVPNSPVTETHAGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGVTAFARSIGDERTRLDRWEVELNTAIPGDPRDTSTPAALAGGYRAILAGDALGPPQRR +QLEDWMRANQT--SSLRPGLPDGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLALMTRS +QADD-PKADN------------- +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000B4DBD84 +---VAQAAQAVEQSLQARVGLAVLDTTDGQLW-QYRADERFPMASTSKALICAALLARGP +---GAMKTAWLVKEEAIQSYAPTTENLIGQHVPASQLCAVTMRNSDNTAANGVLEMLGGP +QAVTSFLRTMGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVHTLQNLVLGDALKAPDRD +RLIDWLRHNEVGGPLLRAGVPESWTVADRTGAAGYGTRGVVAVLWPPERAPLVAAVYITE +TKASMEERNAAIAAIGKAIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000E16C42C +---VAQAAQAVEQSLQARVGLAVLDTTDGQLW-QYRADERFPMASTSKALICAALLARGP +---GAMKTAWLVKEEAIQSYAPTTENLIGQHVPASQLCAVTMRNSDNTAANGVLEMLGGP +EAITSFLRSVGDTVTRLDRNEPSLNEATPGDPRDTTTPQAMVHTLQNLVLGDALKAPDRD +RLIDWLRHNEVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVLWPPGRAPLVAAVYITE +TKASMEERNAAIATIGKAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodovulum kholense TaxID=453584 RepID=A0A2T5UGC0_9RHOB +--ALTDTIARLETALPARIGVAIRDNGSDWGW-SHRDSERFLMASTFKSVLCGAVLDRAD +RGLLSLGDAVAIPPEAILDYAPVAETHVGGTMTLGDLCLATLDMSDNTAANLLIDRLGGP +QEVTAFLRRIGDPVTRLDRTEPGLNLFDPADPRDTTSPAAMAATWQRLLLGDVLSPASRA +RLADWMSHGSVTASLIRASTPPDWTVSDKSGGGRDYTRNLVAMIQAPGRAPVVVAIYLSD +CPADWATRNAAVAEIGAAVI--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium fortuitum subsp. acetamidolyticum TaxID=144550 RepID=A0A100WQU4_MYCFO +---IDDQLAELERRDNVLIGLYAANLQSGRRI-THRLDEMFAMCSTFKGYAAARVLQMAE +HGEISLDNRVFVDADALVPNSPVTEARAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS +QAHDAENLRPLIGELTALV---- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia donostiensis TaxID=1538463 RepID=A0A1W0BGF4_9NOCA +--ELDIALAGIEERKHIRLGVIAHDPGRNLSY-IRRGEERFAMCSTFKVYAAAAILRLHT +QGRLTLDEPVPVAAADIVVNSPVTSAAQGRTLTLAQLCEASLTRSDNTAANLLLRRLGGP +AAVTGFARSLGDTATRLDRWEPELNSAEPGDPRDTTTPTGLADGYRELLLGSGLPAAAKQ +TLTDWMRASVTSGERIRAGLPAGWTAADKTGGGSYGTVNDAGVVWSPGGAPLLLVLLTSS +TTPDAPNDNAALAETTAAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas acidaminiphila TaxID=128780 RepID=A0A0R0E0K1_9GAMM +-----AGFAALEAESGGRLGVCLWHPASGARF-GQRMDERFPMCSTFKFLLAAAVLERAG +RGALSLDQRVPVRAADLLAHSPVTARHVGKDLGVRDLCRATLTTSDNAAANLLLPLVGGP +AGLTAFLRAQGDAVTLAARYEPDANRFAMDDPRDTTSPAAMAGNLQRFVLGDALALAGRR +QLADWLIDNETGDARLRAGLPPGWRVGDKTGSNGRDTSNDIAVLWPRGGTPWVLAAFLQG +STLDDAGRDGILRRVGERAAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Embleya scabrispora TaxID=159449 RepID=UPI000D0F6237 +----LRRLGRLEEQHGARLGVFGFDPATGRYV-GYREQERFPICSVFKTVLVAAVLRDLD +RNGEFLAERIHYTEQDVTRYAPITGRNRAHGMTVADLCAAAITHSDNTAANLLLRALGGP +HAVTRFCRSVGDPVTRLDRVEPDLNSAEPGRDTDTTSARAIAGTYARLTLGTALAPADRA +RLGGWLLANTTGGNRIRAGLPSDWSVADKTGTGAYGTTNDVAITRPPGRGPLVLAVLSTT +SDAHAPADEPLLAEAAALVAAH- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9017 TaxID=2184565 RepID=A0A3P0NZE5_9BURK +--AAQADLATLEKASNGRLGVAVLDTSNGTRI-AYHARERFPLCGTYAVSAAAAILARGA +LDASLLPRRILYRRYDVVAGSPVTESHVDTGMTIAQLCVALLQSGDKGAGNLLMNVLGGP +QAVTAFAHESGDTTFRLDRWEPELNEAAPHDVRDTSTPVAMVDMMKRLLLGDTLGEPQRA +QLTEWLAGGTRGATGIAAGVPPGWRIADKTGSGGYGTTTDVAVVWPPSRAPIVMAISFTQ +PRADAAARADVVASAARIAS--- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces scabiei TaxID=1930 RepID=C9YZ91_STRSW +-----RRLGELEREYAARLGVFAHDTATGRTV-AYRAHERFPLCSVFKALAAGAVLRDLD +RDGAYLGRRIFYTKEYASAYSPITSENVAAGMTVGELCAATVSHSDNGAGNLLLRELGGP +TAITRFCRSLGDRATRLDRWEPELNTAEPWRITDTTTPRAIGGTYARLLLGRALPDADRE +LLTGWLIANSTNVERFRAGLPAGWTLADKTGGGSYGVANDVGVVWPPGRPPLVLSVLSTK +YDPAGPTDNALVARAAGLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Sporosarcina sp. ZBG7A TaxID=1582223 RepID=UPI00057B29D3 +--TMMKKFEQLEKEYDARLGVYAIDTGTKETA-EFREDERFAYTSTSKALATAILLKQNP +--IAVLEEIRTFTNEDIVAYSPITEDFVNEGMSLGKIAEAAIQFSDNTAGNLLFKELGGP +DGFEKALRESGDTVTMAERIEPDLNEAIPGDSRDTSTPKALATSLEVFGISEYLPADKRE +IFTNWLKGSTTGDSLIRAGVPEGWEVGDKSGAGGYGTRNDIAIVWPPNREPIIIAIMSSR +NEEDASFNDELIAKAATVIAQAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. UYPR1.413 TaxID=1080179 RepID=UPI00048A46C0 +---AHERFGQLEASSGGRLGVAAVRTSDGAYV-SYRESERFPMCSTFKLLAVGALLKRST +AERDLLDTRVRYGPADLVANSPITKQHAGEGMSVGELCAAALQYSDNTAANLLLNVIGGT +EVLNEFARSIGDTWFDLARREPDLNASVPGDMRDTTAPRAMMQDAQKLLLDDVLEAPQRE +RLKAWMLGNTTGAGRIRAAVRTGWPVADKTGSGDYGTANDVGVVYSPATA-YVLAIYFTG +VTKETPPQDAIVDEAARIVFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces mirabilis TaxID=68239 RepID=UPI00055A1291 +--DIAAQLRALEEQHTARVGVFGHHLGTRKTV-THRADELFPMCSLFKTLAAAAVLRDLD +QHGEVLYRVVHYTEADLVDGSDKTREHLADGMTIEQLADVAVRYSDNGAGNLLLRELGGP +TAITRFARSLGDPVTRLDRWETELNSAEPDRITDTTSPRAIGGLYGALVLGDALRRPDRD +RLTTWLLNNTTSGTRFRTGLPATWTIADKTGGGSYGTNNNAGVAWTESGDPVVLAVLTTK +PTPNATRDDPLIVDTAKLVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ru73 TaxID=2080748 RepID=A0A2S4XQ97_9ACTN +--STTRQLRALEDKYAARLGVFARNMATGRTV-RHRADERFPMCSVFKGLAAAAVLRDLD +HDGEFLARRLHYTAAEVKKYAPVTGKNLARGMTVGDLCAAAVGESDNAAANLLLRELGGP +TAVTRFCRSAGDGITRLDRWEPELNSAEPWRRTDTTTPRAIGTTYARLVLGRALTPRDRE +RLTGWLVANTTNTKRFRAGLP-GWTLADKTGGGDYGVANDVGIGWPPHGAPLVLSVLSTT +YDPEGPTHDELVAETAELVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseoaurantiacus M045 TaxID=996637 RepID=F3NSY9_9ACTN +---LARRFRALEKEYAARLGVYAHDTATGRTV-RYRADETFPLCSVFKALAAGAVLRDLD +RDGEFLAKRVHYTQKQADDYAPVTGENVAGGLTVGELCAAAVSESDNCAGNLLLSELGGP +SAVTRFCRSLGDDTTRLDRWEPALNSAEPWRKTDLTTPQAIGRTYGRLLLGRALPEADRE +RLTGWLVANTTNTERFRAGLPKDWILADKTGGGSYGVGNDVGVVWPPARPPLVLAILSTK +LDPAGPTENPLVAKAAAAIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Mycobacteroides TaxID=2618759 RepID=UPI0012DF7694 +------ALGALEKDFGGRLGVYAVDTGSNRQV-GLRADQRFIMCSTVKTFIVSAILHRRL +SQPGLLDKRIHYTQADILEWAPITSKHVAEGMTVAELCDATIRYSDNTGANLLIAQLGGP +KETEKYVRSLGDNVSRMDRLEEQLN--IPDRDLDTSTPMQLAANLRTLVLGDGLDPQGRD +LLTDWLKRNTTGDQSIRAGVPAGWTVGDKTGGGFKGESNDIAVIWPPGRAPIIVAALTIP +DDPKSTKGRPTIAEATRIALKAf +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. ER1/6 TaxID=1891920 RepID=A0A1E5MGE6_9MICO +--ATTRAFAALEQQSDARLGVVVIDTADGSSI-GYRADERFAFASTNKAFIAAAVLDATS +--AAGLDEVVHYGRDDLLEYAPVTSRHVDEGMTVRALVDAAVRESDNTAANLLVDRLGGV +DGVSRWLLGIGDDVTRVDRVEPELNTAVPGDERDTTTPARSAADLRAVLVGDALDADDRA +LLLSSMAGTTTGDGTIRAGVPGGWSVADKTGTASYGVRNDIAVARPAGRDPIVLVVFTSH +DRAAAEPSDALVAAATRVALE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Siculibacillus lacustris TaxID=1549641 RepID=A0A4Q9VFE5_9RHIZ +------AVAAIEAKVGGRLGVAVRDSGDGRAF-GHRADERFASCSTGKLLLAAATLLRVD +RGEEDLARRIAYGRADLVPYSPVLEPGLAEGLGVEAIARAAVVLSDNGAANLLLAALGGP +AAMTAWARAFGDEVTRVDRGEPDLNSAEPGDPRDTTTPTAMLGHLDRLLLGAALSPASRA +RLFGWMVESPTGKRRLRGGIPADWTAGDKTGTGGHGTTADVALLQPPGRAPILVAAYLTE +CPAPIADREAALAAVGRLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=UPI00106F4ACF +--------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD +RKVLALSASTQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP +QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVVIAQTLNTLLLGNVLQPSSRE +QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ +TPATMAQRDAAIVRIGESLF--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. B1-1 TaxID=2710648 RepID=UPI0013DB30D6 +------DFAALEKASGGRLGVTVLDTGSGRRLgGHRQDERFPMCSTFKSMLVAHILSLAD +AGRLSLDTRVPIAEQDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP +AALTAFLRAQGDPVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGAGLLPPSRL +QFADWLVDNQTGDACLRAGLGPRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG +ARVDEAQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium angelicum TaxID=470074 RepID=A0A1W9ZKN6_9MYCO +--DLTSRFMELEMKYTARLGVFVAATDPSAEI-AYRAGERFAFCSTFKAPLVGAVLHQYP +--LTHLDKVITYTSDDIRSISPVTQQHVQTGMTIRELCDAAIRYSDGTAANLLLAEIGGT +AAFTGYLRELGDNVSRLDQLEPELNRDAPDDPRDTTTPHAIALVFQQLILGDALPADKKT +MLTDWLARSTTGAKRIRAGFPAEWKVVDKTGTGDYGRANDVAVMWSPSGAAHVVAIYSDR +AGYDAEPSDAVIAEAAAAVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium/Ensifer group TaxID=227292 RepID=UPI00041B345A +----TAAAKSAETRLDARVGLAIYDTGGDRTW-FYNADERFPMASTFKALACAALLNAG- +--NEISNSTVTITEADVQSYAPVTKTMVGKRVSSAELCEITLRTSDNTAANKVLDVLGGP +PAVTSFLRSLGDRVTRLDRIEPELNEGSPGDPRDSTTPRAMADTIQKLILGNALEDRARI +QLTEWLVGNEVGGPLLRAGIPTDWKIADRTGAGGFGTRGIIAVMWPPARDPIVAAIYVAQ +TEASMEDRNEAIADIGRAIASLf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02460 TaxID=1703941 RepID=A0A1Q5K4C4_9ACTN +---TTARLRELERLHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD +RDGEVLEKVIHYTKADCVSDSPVTDTSIASGLSVARLCDAAICDSDNTAGNLLLRELGGP +QAVTRFARSLGDRVTRLDRWEPGLNTAEPGRVTDTTTPSALARDYARLVLGDVLERRDRA +LLTHWLLNCRTSDTRFRAGLPPEWTVADKTGGGSYGSCNDVGVAWTREGAPVVLAVLTSK +PASGAAGDHPLVRDVAKALA--- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. (strain ATCC 39116 / 75iv2) TaxID=385957 RepID=UPI000309E28E +-----VDFADLEARFDARLGVYAIDTGTGREI-AHRADERFNYASAIKSLLAGAVLRRNV +----DLDKVVTYTDAEIQPNSPITKDR--RSVTVREAAEAALLQSDNTAANLLFAEVGGP +AGLAAVLREIGDTTTHPDRLEVELNSAIPGDVRDTSTPRAMAGSLRAFLLGEALPAGKRD +LLAGTMRRNKSGTELIRAGVPSEWPVADKTGTGDYGTRNDIGVIWPPNRAPIVLALMSSR +ATADASYDNKLLAEATSRVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Lysobacter enzymogenes TaxID=69 RepID=A0A1J1EE19_LYSEN +--ALGERLAKLEQRSGGRLGVAVLDTADGRRW-ATRGDERFAMCSTYKLPLVAAVLRKAE +LGEIDLHARIAVPPAALVPYSPATAPIARAGASVAQLCEASMTISDNTAANLLLPLVGDP +AGVNRFLHGIGDDISRMQRTPGAPLRA--GDANDTTTPNAMLATMRRLLLGDALNPASRQ +RLTEWMLASKTGDTRLRAGLPQRWRVGHKTGTGQ-GTANDIAIVWPGRRKPVLIASYLTD +AWGDDELRNAVLADVARTLAAHw +>[subseq from] Beta-lactamase n=1 Tax=Microbispora hainanensis TaxID=568844 RepID=A0A544YMQ3_9ACTN +--DVTAALRKLEASFKGRIGAYAIDTATGKTI-GYRSGERFPLLSTFKAVAAGAVLARTT +-DRELTRKVVHWTAAEVKSNSPETGKHVKDGMTLAELCRAAIIYSDNTAGNMLLKRIGGP +RGLTRYFRTLKDPVSRLDRWETDLNVWSPKERRDTTTPASVARDLRALTTGGALGAKDRS +RLIGWLRDNTTGDARIRAGLPKTWIVGDKTGTGGYGTANDIAVVWPAGNAPIIMAIYTNR +RAADGATADSVVARTATLLA--- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase KPC n=1 Tax=Mycobacteroides franklinii TaxID=948102 RepID=A0A4R8QZ10_9MYCO +---KSTELASLEKDFGGRLGVHALDTGSGDTL-SHRANERFIMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYTQADIVEWAPIASQHVGEGMTIAELCDATIRYSDNTGANLLIAELGGP +KETEKYVRSLGDNVSRMDRLEEDLN--IPDGDLDTSTPLQLATNLRRLALDEGLDAQGRD +LLTDWLKRNTTGDQSVRAGVPAGWTVGDKTGGGFKGETNDIAVIWPPGRAPIVVAVLAIP +DDPKSTKGKPTIAAATRIALKAf +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. PA05 TaxID=2604466 RepID=A0A5D0P2H2_9ACTN +--AVKKELRALEVAFKGRIGAYAIDTATGKTL-TYRAGERFPMLSTFKAPLCAAVLHLAR +RQPGLMSRRITWTAADMKPNSPVTEKHVKDGLTVSELCVAAVTQSDGTASNLLMKLIGGP +KGMTAFFRTLKDPVSRMDRWHPELNDWTPKDKRDTTTPAAMAADLRALATGTALHAKDRE +QLVAWLLASKVGAERIPAGLPGTWTIAHKTGTNSFGGGNDIAVIWPRKGAPIIMAVYTNR +TP-GLPTDNRTIARTATVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Lentzea albidocapillata TaxID=40571 RepID=A0A1W2CYV7_9PSEU +-----DALSELEKKFDARLGVYAMS-DNGSTI-EHRADERFAFCSTFKGLAAAAVLHRNP +--MSHLDTVVTYTEADLMKSSAITRQNVRTGMKLRDLCDAAVRYSDGTAGNLLLRDLGGP +AELTKYLRELGDTETRMDRVEPAITSATPGDPRDTATPRSLGTDYQRIVLGDALEPAKRD +FLTGLLERSVTGAKRVRAAVPAGSRVANKTGTGEHGTVNDIAVVWPPGREPVLIAIMSSK +SAADAKYDEALVAEAAAYVVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium asiaticum TaxID=1790 RepID=UPI00056D43C2 +--DLSHQFDQLERRYEGRLGVYVPE----PVI-AYRADERFAFCSTFKAPLAAAVLHQYP +--LDHLDKLVSYRRSDINSVSPVTEQHVDTGMTVGQLCDAAVRYSDSTAANLLLAEVGGP +AGFTTYLRTLGDNVSRLDQPEPQLNRDAPDDPRDTTTPHAIALVFQQLLLGAALPADKRA +LLVDWMTRNTTGGKRIRAAFPPDWKVADKTGSGDYGRTNDVAVVWSPSGAPHVIAIYSDF +VGYDAQPNEGFVADAARIVAS-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-24720 TaxID=1476876 RepID=UPI00068F6B41 +--RTARELRALEREHSARLGAYAHDTATGRTV-VYRPDERFPMCSLFKTIGAAAVLRDLD +RRGEFLARRIRYTAQYVEANSPITGRNLSRGMTVAELCAYSITHSDHTAANLLLRELGGP +GAVTRFCRSIGDPVTRLDRWEPELNSAEPWRGTDTTTPRAVGRTYARLVLGDALGPCDRR +LLTGWLLANTTSGERFRAGLPADWTVADKTAGGSYGGNNNAGIAWPPGRPPVVLAVMTTK +PDRDAPADDPLVARTAGVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Microbispora sp. Gxj-6 TaxID=2614688 RepID=A0A5J5JXS6_9ACTN +--AVRKALRKLEASFRGRIGAYAIDTATGSTI-GYREGERFPLASTFKAFAAGAVLAGTT +-EAELTRQVVHWTADELKPYSPDTGKHVDDGMTLAALCRAAVVHSDNTAGDMLLKRVGGP +KGLTRYFRSLGDAVSRLDRWEPELNVWSPKERRDTTTPLAIARDLRALTAGGALDAADRS +RLVGWLRGATTGGKRIRAGLPPKWIVGDKTGTGGYGTANDIAVVWPADAAPIILAIYTNR +LAAGGSADDEVVARTAAVLV--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium flavescens TaxID=1776 RepID=A0A1E3RC76_MYCFV +---LESRLRDLEREHHALIGVFATNLDTGRTV-AHRAAESFAMCSTFKTYAAARVLQLVE +RGELSLDRRVRVDAADIVAHSPRTQPRVAGDMTVDELCQAAVQVSDNAAANLLLRTIGGP +PAITAFARSIGDQRSRLDRWELELNAAVPGDPRDTTSPEAIGGGYRALLTGTALAAPQRE +LLQRWMRANET--SSMRAGLPAGWTTADKTGSGDYASTNDVGVAYGPNGERLLLSLMIRT +AGADAPGLRPVIGQLAALLV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A109EIH9_9BURK +--TAHAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAVLWPPSRAPIVMAVSFTL +PQADAAARADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia steynii TaxID=1245441 RepID=UPI00087FB987 +---ARERFEQLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM +AERSLLDERVRYGDADLVANSPVTKRHVGESMTIGELSAAALQHSDNTAAKLLLTAVGGP +EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE +QLKAWMLGNVTGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVVAVYFTG +VMKQTLPRDEVVVEAARIVFD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QE32_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLGLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=3 Tax=Streptomyces TaxID=1883 RepID=A0A4D4LT52_STRAX +--RLYGRLRELEREHSARLGVFARDMATGRTL-LYRADERFPVCSVFKTLAAAAVLRDLD +HDGEFLARRIRYTEQYVKDYGPVTGRNLAAGMTVAELCAAAVSDSDNAAGNLLLRELGGP +TAITGFCRSIGDGRTRLDRWEPDLNSAEPWRDTDTTSPRAIGKTYARLILGDVLPPQDRT +RLTNWLIANTTNTARFRAGLPADWILADKTGGGNYGVANDVGVVWPPNRSPIVMTVLTTK +HAAAGPSDSPLVARTAELLA--- +>[subseq from] Beta-lactamase n=1 Tax=Ruegeria conchae TaxID=981384 RepID=A0A497ZTK6_9RHOB +---LIQNTRLWEHRLDARIGVLLYETDAAWEV-SHRADELFPMSSTFKPLLCGAILAGVD +SGAVDLSENVAIQTSDLVEYSPVTSEHVETGMTIGALCQATMTISDNAAANLLLKQLGGP +AGLTEFLRATGDGTTRLDRWETALNEATPGDPRDTTTPRAILETIERLLFDEVLSPASAA +QLGQWMIDDQVADGLIRAHLPNSWIIGDKTGAGGYGSRAIIAFLQTPEPRTYMAAIYLTE +SDASFPERNAVLSDIGQAMI--- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI000893B2C4 +-qSVEQEIKGIESSLSTRIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACLATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F58A092 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSDSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMAGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PDAAAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter persici TaxID=1076596 RepID=A0A252APJ1_9PROT +-------IAAYEKATGGRIGVYACNLATRQRL-TWRENDRFALCSTFKVSLVALVLQRVE +QGKGRLDEAVSYTKADIERYAPVAQASLEAGMSVRALCQAAIEQSDNACANLLLARVGGP +ENLTRFWRSLGDQATRLDDWEPDLNRVPPGSVRNTTTPAAMAGVLEHLLFGEVLSASSRL +LLTEWLKGCQTGRNRLRAGFPAGWEVGDKTGTNGQDAAGDCAVAWPSPRTPLIVCVYTRG +GHPAEDQFRAAFAGIARLA---- +>[subseq from] class A beta-lactamase n=1 Tax=Beijerinckia sp. L45 TaxID=1641855 RepID=UPI00131C5855 +-------LAAYELVSGGRIGLYAGNIRTGAKI-LWRADERFVMCSTFKASLAAFVLARID +QGKDRLYAMIAYGPGDLMDYAPVAKRNLAAGMSVVAMAEAAVTLSDNTCANLLLARVGGP +AALTRFWREIGDDTSRLDHNEPALNRSPPGDPHDTTTPGAMAGTLRRLVLGDALSAESCA +RLTGWMVACTTGANRLRGGLPKDWRIGDKTGNNGKDASGDIAIVWPKTDTPIVICAYTQG +GAPTAPALEAVFADIGRLVAQ-- +>[subseq from] Beta-lactamase Toho-2 n=1 Tax=Escherichia coli TaxID=562 RepID=BLT2_ECOLX +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTARAGADVASLRWVMRWAKPS--G +AVGDVAQRQYDRAAGIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium wolinskyi TaxID=59750 RepID=A0A132PIK8_9MYCO +----DDQIGELERRHNAVIGIYAVNLDSNRIV-SHRADDMFAMCSTFKAYAAGRVLQMVG +RDQLSLDNRVFVDPDAIVMNSPVTEPRAGSEMTLGELCAAALQRSDNTAGNLLLKTIDGP +AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAIGYRALLVGDALSPPQRR +QLEDWMRANQT--SSMRAGLPAGWTTADKTGSGDYGSTNDVGVAYGPAGQRLLLAMMTRS +QTDDPKAANPLIGELT------- +>[subseq from] Beta-lactamase n=1 Tax=Jiangella alkaliphila TaxID=419479 RepID=A0A1H2KCA7_9ACTN +----DPAVRELERTHDVTLGVSATNLATGARL-AHRAGDRFPILSVFKSIAAAAVLRDLD +--EARLDHRVWFPPADILANSPITAEHVDTGITVAELCDAAIRFSDNAAGNLLLREIGGP +RGLTAFARSIGDGATRLDRWELELNSAEPGDEQDTSTPAALARTFAGLLVGDLLRPADRR +RLRSWMLANTTSGPRFRDALPDGWRLADKTGAGDYGTNNDAGVAWNPAGEPIVIVAMSRR +TERDSVRVDAALADVARLVVR-- +>[subseq from] Beta-lactamase n=2 Tax=Mycolicibacterium litorale TaxID=758802 RepID=A0A4R8IWY2_9MYCO +------ALAELERRFGARLGVYGVATDTGATV-AYRADERFAFCSTFKALAAGAVLHRHS +--VAHLDTRVGYTEHDLMKSSVITRRHVATGMTIGELCDAAVRFSDGTAGNLLLRVLGGP +EQLTAYARSLGDTVTRMDRVEPHVADAVPGDVRDTSSPRALTEDIRALLVGDALGPAERA +VLQDLMQRNATGMERIRAGLPPDWTVADKTGTGDFGTLNDIAVVWPPHRAPLAMGIMSTK +TSKDAAYDPALLAEAARYVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia suismassiliense TaxID=2077092 RepID=UPI000D1F84FF +--------VELEQQFGARLGIYALSTGTNRTL-THRADERFAFCSTFKALAAAAVLHHNP +--LTHLYKPVTVTKADIRSISPVTERRVDTAMTIGELCDAAVRFSDGTAGNLLLDDIGGP +AGLTDYLRGLGDTVSRMDQYEPELNRDPPGDDRDTTTPRAIAADYQHLILGSALPEDKRA +ILTDWLVRNVTGAKRIAAAAPAGWTIADKTGTGNYGRANDIAIVWPTAHPPLVLAIMSDR +TGYDAEPSSELIAEAARHIF--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium syngnathidarum TaxID=1908205 RepID=UPI00095E9D0B +----DDGIAELERRNNAFVGLYASNLDSGRTL-THRADEMFAMCSTFKAYAAARVLQMAE +HGEVSLDNRVFIDREAIVPNSPVTETRAGGEMALAQLCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPSALAVGYRAVLAGDALSPPRRR +LLEDWMRANQT--SSMRSGLPEGWTTADKTGSGDYGSTNDAGIAFGPEGQRLLLVMMTRS +QA-DDPKAEPLIGELTA------ +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium aurum TaxID=1791 RepID=UPI000B35AFC0 +---WEEQVRELEARYNAFIGVYAANLDSGVTL-ENRADETFALCSTFKAYAAAAVLQRVA +AGELSLEQRVFVDPAALLPNSPVTGEHAGAEMTLAELSQAALQRSDNLAANLLLETLGGP +SAITAFARSIGDDRTRLDRWEIELNSAIPGDPRDTGTPRALAAGYRNLLVGQALPAEQRE +LLDGWMRANQT--SSMRAGLPPDWTTADKTGSGDYGTTNDAGVAYGPDGTRLLLTIMTRT +QSADAEGLRPLIGEVAAAAL--- +>[subseq from] Class A beta-lactamase n=1 Tax=[Pseudomonas] mesoacidophila TaxID=265293 RepID=A0A2A4FIX2_9BURK +--AAQSQLDALEQASNGRLGVAALDTASGARI-AHRSRERFPLCGTFAVVAAAALLVRGA +LDASLLPRRILYRRYELVPGSPVTERYADTGMTIGQLCEAMLHSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPGDERDTSTPLAMAETMRRLLLGDALGEPERA +QLTRWLTGSANGVKGIRAGVPSDWRVAGKAGTGGYGTTSDVAVLWPPSHAPLVIAVSFTQ +PAADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderiales TaxID=80840 RepID=D2K8A5_9BURK +-qQVEQDVKAIEVSLSTRIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGHSIFDVy +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas smyrnensis TaxID=720605 RepID=UPI0002E33B45 +--DLERQLGELERSADDRVGVALMNVATGAVA-SHRGHERFLFNSTGKCFIAAAVLARVD +EGRETLDRRIVIEEGDLVGWTPVTEKRLGEPLTVAELCQAAVAWSDNAAANALIESVGGP +EAVTAFLRAIGDDTTRLDRVEPALNTDHPGDERDTTTPLAMMATLRTLLLGDALSPSSRH +QLASWMIEGKVGDARLRAGMPSSWLVGEKTGTNGVGNASDIGIAWPGDRGAVIAVAYTFM +PNATGAERDETIAAVGRLAA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Cryptosporangium aurantiacum TaxID=134849 RepID=A0A1M7TYS9_9ACTN +------DLTALETSLGTLIGAWALDTGNGVTV-SHRADERFGLNSTFKVLAAAAVAQRGG +-----LDRVVRWTRADLVAHSPITEQHVDDGLPLEQVCAASVTHSDNAAGNLLLKELGGP +GGVTRFVRTLGDDATRLDRWEPALNAFTPGDPQDTTTPAAIGRTLQRLVLGDGLDGTARA +LVTSWLRANTTGNLRIRAGLPSDWTVGDKTGTGDYGAANDIAVAWPPSGAPIVYAIYTRR +PTEDEERDESVVARTATILT--- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax temperans TaxID=80878 RepID=A0A543L1K6_9BURK +--TWNSAMEGIEHNAQGRLGVSMLDTETGLAL-GWRQDERFAMCSTFKLLLAGWMLSLVD +QGRENLNARVHYAPADVVEYSPVSAPRAGPGLTVGELCSATVSLSDNTAANVLLERHGGP +AALTRYLRMLGDPITRLDRNEPTLNEAAIGDVRDTTTPRAMLQTMQKLVLGESLSASSRA +WLQRWLIETSTGDKRLRAGAP-GWKVGDKTGTAGSGTANDVAVLWPPHRGAVLVTCYLTR +SAVAPEQRDAAIAAVGRAVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax temperans TaxID=80878 RepID=A0A0D7KD85_9BURK +--TWNSAMEGIEHNAQGRLGVSMLDTETGLAL-GWRQDERFAMCSTFKLLLAGWMLSLVD +QGREKLDARVHYAPADVVEYSPVSGPRAGTGLTVGELCSATVSLSDNTAANVLLERHGGP +AALTRYLRALGDSITRLDRNEPTLNEAAIGDVRDTTTPLAMLQTMQKLVLGESLSASSRA +WLQRWLIETSTGDKRLRAGAP-GWKVGDKTGTAGSGTANDVAVLWPPHRGAVLVSCYLTR +SAVAPEQRDAAIAAVGRSVVS-- +>[subseq from] Beta-lactamase n=1 Tax=alpha proteobacterium U9-1i TaxID=1605283 RepID=A0A1V1PML8_9PROT +------RIAAIEARLGARIGVAALNTASAAWI-GHRIQERFAMASTFKWLLAAQMLQMAE +QMPEFLQQRILYDEADLLDYAPTARAHLARGMTVEECCEAIVVVSDNTAANLLLVGASGP +AGFTSFIRANADSVTRLDRTEPALNENALGDERDTTTPDGMARSLRNVLVGEVLNPASRE +KLIGWMVASTTGLQRLRAGLPSDWRVGDKTGSGARGAVNDVAIAWPPGRAPIVIASYMSD +GEADTATRSAAHAEIGRIIAETw +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium peregrinum TaxID=43304 RepID=A0A1X2BCH1_MYCPR +---VDDQIAELERRDNALIGLSATNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMAG +RKQISLDNRVFVDPGAIVPNSPITETHAGSEMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAIGYHQILAGDALSPPQRR +QLDDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPNGQRLLLAVMTRS +QADDPKADNPLIGELT------- +>[subseq from] Uncharacterized protein n=1 Tax=Halomonas huangheensis TaxID=1178482 RepID=W1NBR6_9GAMM +--DLGAEFEALEQRHSGRLGIALMNLSSGVVA-SHRGDERVLFNSTIKTVIAAAMLSRVD +RGEISLDSRLVVSESDLGGWTPITEQHLGEPMTVAELCQAAVAWSDNAAANVLVTDAGGP +AAITEYLRSIGDEVTHLDRMEPELNEDHEGDERDTTTPLAMLQTLRTLIFGDTLSPQSRH +QLVAWMVEGKTGDNRLRAGMPPNWLVGEKTGTNSVGNANDAGVAWPMDRGAVIAVAYTWL +PDAEPEQRDEVIAEIGKLA---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseoaurantiacus TaxID=68213 RepID=UPI000997E7D7 +---LARRFRALEKEYAARLGVYAHDTATGRTV-RYRADETFPLCSVFKALAAGAVLRDLD +RDGEFLAKRVHYTQKQADDYAPVTGENVAGGLTVGELCAAAVSESDNCAGNLLLSELGGP +SAVTRFCRSLGDDTTRLDRWEPALNSAEPWRKTDLTTPQAIGRTYGRLLLGRALPEADRE +RLTGWLVANTTNTERFRAGLPKDWILADKTGGGSYGVGNDVGVVWPPARPPLVLAILSTK +LDPAGPTENPLVAKAAAAIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonadaceae bacterium SI-3 TaxID=2079806 RepID=A0A3T0SG48_9GAMM +--ALRETVASIEARTGGHIGVSVTALESGQSW-SHRGDERFPIASTFKAFSCGHLLALAD +RDEIKLDTRVRFDETDLQSYSPITKDRVGRSMSLFDLCSATTSMSDNTAANLILRNTGGP +QGFTTFMRSIGDAVTRLDRYEPELNDVGPGEERDTTTPMAAARSLETLLLGDSLSTHSRE +QLKAWLINNKVGGPLLRASLPESWKIADRTGSGGYGSRGVIAVIWPQGSEPVIVAVYLTG +TTLTLEERDAAIAEVGAALV--- +>[subseq from] Beta-lactamase n=1 Tax=Tardiphaga sp. YR296 TaxID=2135488 RepID=A0A420AKL9_9BRAD +---APAALQAYERDTGGRIGVYAENLKTGAKI-AWRAHERFVMCSTFKASLAACVLARID +RGEDKPDQMISYAAADLLDYAPVARDNLAKGLSVADMCKAIVELSDNTCANMLLARVGGP +AALTAFWTKTGDSVSRLDHNEPLLNRSRPGNPQDTTTPAAMAGNVKRFVTGNVLTPTSRD +QLTDWMVNCKTGDKRLRAGLPKTWKIGDKTGNNGKDAAGDIAVTWPKPDQPVVIAAYTQG +GTPTAPQLETVFTGIGEMV---- +>[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=A0A508X6R1_9RHIZ +--DVTERLRQLEERTGGRLGVAVLDMETNISF-GYRETERFAMCSTFKALAAACALARVD +RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTIAELCEAAITISDNAAGNLLLESFGGP +QGLTSWLRSIGDNTTRLDRTEPDLNEARKGDPRDTTTPAAMLDTLGKLALGSVLSENGRG +QLVDWLVANETGDARLRAGLPKDWRIGDKTGTSSTGA----------------------- +----------------------- +>[subseq from] class A beta-lactamase n=2 Tax=Burkholderia TaxID=32008 RepID=UPI000408A35D +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGEVLHEPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAVLWPPSRAPIVMAVSFTQ +PDAAAAARADVVTAAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas sp. NML171202 TaxID=2480817 RepID=A0A4Q8LLI6_9GAMM +-----RDFAALEQVSGGRLGVTLLEVGTGRRM-GRRQDERFPMCSTFKALLAAHVLSLAD +AGALSLDERLPIRQAQLLSWAPESERHVGKDLTVRDLCRAVVTNSDNTAANLLLARTGGP +PALTAFLRKQGDAVTRSDRYEPEMNNFAPDDPRDTTSPAAVAASLARFAVGDGLSKASRA +QYADWLIDNQTGDACLRAGLGKRWRVGDRTGSNGRDTRNDLAVLWPLGGTPWVLVALLQG +ARVDADQRDAVLARVGALA---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia latens TaxID=488446 RepID=UPI00075F025C +---AQAELAALEKASNGRLGVAALDTSSGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRVLYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQAGDKGAGNLVMGVLGGP +QAVTSFAHESGDTTFRLDRWEPELNRAAPGDERDTSTPLAMVDTLQRLLLGDTLREPQRA +QLTEWMTGGARGATGIAAAVPPGWRIADKAGSGGHGTTTDVAVLWPPSRAPIVLAVSFTQ +PAADAAARADVVASAARIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium brachiatum TaxID=269660 RepID=A0A1I3N5K7_9RHIZ +-eAVESALAAIEKRLGGRLGVSAGT-PERVFL-RHRADELFPMCSTFKVLAAACVLVRVD +AGTESLDRLVTYGNDVLLSYAPVIRKGLEAGMTVADLCAAALEWSDNSAANLLLAALGGP +EALTLWLRGIGDTVTRLDRNEPTLNTALQGDPRDTTSPEAMRATLARLLLGPSLSAASRA +RLEAWMVASQTGFKRLRAGLPPDWTAGDKTGTGDHGTVNDVAILRPPGRAPILACVYVTG +AQAPTEVVEVAHAEIGRLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI0009F34319 +---VAQAAQAVEQSLQARVGLAVLDTTDGQLW-QYRADERFPMASTSKALICAALLARGP +---GAMKTAWLVKEEAIQSYAPTTENLIGQHVPASQLCAITMRNSDNTAANGVLEMLGGP +EAITSFLRSVGDTVTRLDRNEPSLNEATPGDPRDTTTPQAMVHTLQNLVLGDALKAPDRD +RLIDWLRHNEVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVMWPPGRAPLVAAVYITE +TKASMEERNAAIATIGKAIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium kansasii TaxID=1768 RepID=UPI0007B53846 +--DVRGRFAELEHRYAARLGVYVPASGTTAAI-AYRADERFAFCSTFKGLLVAAVLHQYP +--LSHLDTVVTYTGADIRSTSPITQQHVATGMSVGELCDAAIRYSDGTAANLLLADIGGT +SAFTGYLRSLGDSVSRLDQEEPELNRDPPGDERDTTTARAIALDYQQLVLGDALPVDKRA +MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPSGVPHVVAILSDR +AGYDAEPSEALVADAARCVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia donostiensis TaxID=1538463 RepID=UPI0011159EF2 +--ELDIALAGIEERKHIRLGVIAHDPGRNLSY-IRRGEERFAMCSTFKVYAAAAILRLHT +QGRLTLDEPVPVAAADIVVNSPVTSAAQGRTLTLAQLCEASLTRSDNTAANLLLRRLGGP +AAVTGFARSLGDTATRLDRWEPELNSAEPGDPRDTTTPTGLADGYRELLLGSGLPAAAKQ +TLTDWMRASVTSGERIRAGLPAGWTAADKTGGGSYGTVNDAGVVWSPGGAPLLLVLLTSS +TTPDAPNDNAALAETTAAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium sp. P9-22 TaxID=2024613 RepID=A0A5A7ZHD5_9MYCO +--TLEDQIRELEARHNAFVGLYAANLQSGFTV-EHRADEAFALCSTFKTYAAARVLRGVA +DGELTLDQQVFVKPEGLLPNSPVTGERLGQQMTLAELSQAALQRSDNLAANLLLETIGGP +QAITAFARSVGDDRTRLDRWEIELNSAIPGDPRDTTTPRALAAGYRNLLAGDALPPAQRE +LLDGWMRANQT--SSMRAGLPPGWTTADKTGSGDYATTNDSGIAYGPDGARVLLTIMTRT +QTADAEGLRPLIGEVAALVL--- +>[subseq from] Beta-lactamase n=1 Tax=[Mycobacterium] stephanolepidis TaxID=1520670 RepID=A0A1Z4EYY3_9MYCO +-----SELASLEKDFGGRVGVFALDTGSGATL-GHRANERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYAQSDLMEWAPITSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD +LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWSTGRAPIVVAVLTVP +DDPKSTQGKPTIAAATRIALKAf +>[subseq from] Beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A0F7NE15_9ACTN +-qRATREFKDLERAHDARLGVYAVDTMTGQEV-AYREGERFAFASTVKAFEAGAVLRKRK +--LAGLKKEITYDRSDLVANSPITEKHVDDGMTLGELCDAAVRYSDNAAANLLFEEIGGP +RALQSFLRETGDDTSRMERIEPALSDWEPDAVRDTSTPRALAGNLRAFVLGDVLDAPERA +RLAEWLRTNTTGDASIRAGVPKDWKVGDKTGTAAFGGRNDIAVVWRPDAAPLVVAVLSHG +TDRDAEPDDELIAKAAAVVSD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 4121.5 TaxID=1938847 RepID=A0A2N0EMU9_9ACTN +--DLGDALAALEREHGARLGVFAHDTGSGATV-RHRADELFPLCSTFKTLAVAALMHAGD +----DLAARVHYTDQDVADYAPVTGR--TRVLTVAELCAAAIEFSDNTAANLLLRRLGGP +SAVTRFCRSIGDRVTRLDRWEPALNSAEPGRVTDTTSPRALARSYARLTLGDTLAPAHRA +RLTAWLRATTTGANRLRAGLPAAWALADKTGTGSYGTANDAGLARPPHRAPIVLTVLTTK +PTPDAAPDEPLIARTAALLA--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. ER1A TaxID=1517681 RepID=A0A084TBK1_9VIBR +--TLDESIASIEQRISGRIGVSVLDSSNQQQW-HYRGNERFPMMSTFKTLACAKMLHDVD +SGELDKNALAPITSDKLIPWSPVTEKMVGSSITVSKACEATMETSDNTAANIVLHSIGGP +QGLTEFLRLNQDDVTRLDRIEPELNQALSGDKRDTTTPNAMNTTLHRLLFEGALNQGSKN +QLIAWMQGNTVSDSLLRSILPKGWSIADRSGAGANGSRGFTGAIWADNHKPMIISIYLTQ +TDLSMSERNQIINEIGGLIFETy +>[subseq from] class A beta-lactamase n=1 Tax=Achromobacter agilis TaxID=1353888 RepID=UPI001011C27E +--AFDQALAELEASSQGRLGVGLLDTASGQVA-GYRGDERFLMLSSFKTLAAAYILARAD +RGEDQLTRRIPITEADLQEHAPVTRRHVGPQMTLAELCEATVTTSDNTAANLMHRSYGGP +QALTRYLRSLGDIVTRHDRYEPELNRPHAGEPLDTTSPHAMSATLNALLFGQALKPQSRQ +LLQSWLLASITGGKRLRAGFPADWKVGEKTGTYSKVGANDAGFAQAPGGAPIIVCVYLET +TAIPMDERDRIIAEVGKRVA--- +>[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis benevestitus DSM 16100 = ATCC BAA-896 TaxID=1121022 RepID=V4PFB9_9CAUL +----AQRMIEIQKRHGGRVGVSALNSEANGSL-SIQSTELFAMCSTFKWVLAAAILQQVD +QGKLKLAQTVKYGPKDLLDYAQVTKMHVAKGMTIGDLCSAAVALSDNTAANLLLPLVGGP +AGLTAFVRGLGDSITRFDRNEPSLNTNIDGDERDTTTPEAMSNLLRTVFTGPLLKPESLK +PLKDWMVATTTGRGRIPSGLPAGAVLGHKTGSGANNATNDVGVIWLPGKDPVFLSIYTTG +GTLDDAGRDQVIADITRLVFD-- +>[subseq from] Beta-lactamase n=1 Tax=Achromobacter agilis TaxID=1353888 RepID=A0A446CD07_9BURK +--AFDQALAELEASSQGRLGVGLLDTASGQVA-GYRGDERFLMLSSFKTLAAAYILARAD +RGEDQLTRRIPITEADLQEHAPVTRRHVGPQMTLAELCEATVTTSDNTAANLMHRSYGGP +QALTRYLRSLGDIVTRHDRYEPELNRPHAGEPLDTTSPHAMSATLNALLFGQALKPQSRQ +LLQSWLLASITGGKRLRAGFPADWKVGEKTGTYSKVGANDAGFAQAPGGAPIIVCVYLET +TAIPMDERDRIIAEVGKRVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI0004C91006 +----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD +HDGSQLARVIRYTEADVTKHAPVTKDHIDTGMTIRDLCDATIRYSDNCAANLLLRELGGP +TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA +LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDGAPVLLTALTHK +PSPTAPGDTPLIIKLATV----- +>[subseq from] Beta-lactamase n=4 Tax=Streptomyces TaxID=1883 RepID=BLAC_STRCE +----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD +HDGSQLARVIRYTEADVTKHAPVTKDHIDTGMTIRDLCDATIRYSDNCAANLLLRELGGP +TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA +LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDGAPVLLTALTHK +PSPTAPGDTPLIIKLATV----- +>[subseq from] class A beta-lactamase n=1 Tax=Actinokineospora terrae TaxID=155974 RepID=UPI000B8031F1 +---LAREFAQLERKYDARRGVYAVDTKRDRTV-SYQADERFAYASTSKAFAAALVLDATT +--PQQLEEPVPIRAADLVANSPVVERAVGGTMTWRELCDAAVRYSDNAAGNLLLRSLGGP +AGLQA---GLGDQVTSADRYEPDLSSAIPGDPRDTSTPRTMATNLRKFTVDTALPEEDRA +MLDDWLRNNTTGTDVIRAGVPRDWVVGDKTGSADYGGRNDIAVLWPPGRDPIVIAVLTSR +DKEGAERLDALVADTARIVA--- +>[subseq from] Beta-lactamase n=2 Tax=Leifsonia sp. Leaf336 TaxID=1736341 RepID=A0A0Q5LPL0_9MICO +--AAQRQFAALEAEHDARVGVYAVDTGTGAHI-AYRADERFGYASTYKALAAAAVLADPP +--AGGLDSPVGYTSDELVAYSPITEQHTSTGMTLRELADAAVRYSDNTAGNLLLTALGGP +AGFQEALRELGDTVTRPERAEPALNELTPGGTDDTSTPRALATDLREYALGSALPADARA +QLKTWLVGNTTGDALVRSVAASGWTVGDKTGSADHGTRNDIAIIWRDAGTPIVIAVLTDH +TAVDADTDDALVASAAEAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica subsp. enterica serovar Albany TaxID=211968 RepID=Q2QCK1_SALET +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHPAPIIVSIYLAQ +TQASMAERNDAIVKIGHSIFDVy +>[subseq from] class A beta-lactamase n=1 Tax=Paracoccus sp. PAMC 22219 TaxID=1569209 RepID=UPI0005A5F17B +-----EAARAVETELGGRVGVALRRQGSPEGQ-GYRADERFPLSSTFKAPLCGAILTLVD +AGEDQLDRVIGYTSGDLVTYSPVTETR--DAMSVAELCEATLTLSDNTAANLLLDSVGGP +KGFTDYLRAIGDETTSLDRWETDLNEGAPGDPRDSSTPEAMIATLEKMLFGPVLSEHSQQ +QLEAWMRANAVADDLIRASLPQGWIIADRTGAGGHGSRSIVALIRTPQDEPWLAAVYLTG +NEADMANRNAAIARIGQAIVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas sp. ZOR0011 TaxID=1339230 RepID=UPI000647D798 +--ALSAQMKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD +AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP +AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSASRQ +QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ +TEATFDERNAAIVTIGKSIFDTf +>[subseq from] Beta-lactamase n=2 Tax=Burkholderiales TaxID=80840 RepID=A0A1E3YU33_9BURK +--EWNETLASIERTAQGRLGVAMLDTGSGLQL-GWRQDERFAMVSTFKAVLAGWMLALVD +QGKERLDARVHV-----VAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANLLLARHGGP +AGFTAFVQSLGDSITRLDRTEPTLNEAKVGDPRDTTTPLAMLQTLQKLVLGDVLTPPSRA +WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVMWPPGGAPVLVTCYLTR +STVKPEQRDAAIAQVARAVAA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. or43 TaxID=2478957 RepID=A0A652LRT0_9ACTN +----LARLRELERVHGARVGAFAYNVATGAFV-RHRADERFPVLSTFKTLAAAAVLRDLD +RDGEVLGRLVRYTKEDCVPDSRITDTCLASGLTIERLCEAAVCDSDNTAANLLLRELGGP +RAVTRFSRSIGDPVTRLDRWEPDLNSAEPGRRTDTTTPAAIARDYARLVLGDALEARDRQ +RLTGWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYGSCNDVGIAWTPDGTPVVLAVLTTK +PDGDAAGDHPLVARAAEALA--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Pseudoxanthomonas TaxID=2645906 RepID=UPI00102D70E0 +-----RDFAALEQVSGGRLGVTLLEVGTGRRL-GRRQDERFPMCSTFKALLAAHVLSLAD +AGALSLDERLPIRQAQLLSWAPESERHVGKDLTVRDLCRAAVTNSDNTAANLLLARAGGP +PALTAFLRKQGDAVTRSDRYEPAMNDFALDDPRDTTSPAAVAASLARFAVGDGLSKASRA +QYADWLIDNQTGDDCLRAGLGKRWRVGDKTGNNGRDTRNDLAVLWPLGGTPWVLVALLQG +ARVDADQRDAVLARVGALA---- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. V23 TaxID=2044878 RepID=A0A2S4LMT0_9RHIZ +----GAALARIAGDLGGRAGIAVLDTGGGPAL-LHDAEGTFPLCSTFKLPLAAAILARVE +AGRERLARRLAYGEADLDTYAPVTTHALRAGMSVEALCAAALVWSDNTAANLLLGALGGP +AALTDFCRDLGDPVTRLDRTEPDLNSAVPGDPRDTTRPAAMAATVGKILLGPSLSEAGRA +RLEGWMTASRTGTKRLRAGLPADWGIGDKTGSGAYGTANVVALLRPPARAPLVAAVYITG +SDATSEARDAAHAAIGRVIATAy +>[subseq from] class A beta-lactamase n=1 Tax=Lentzea sp. NEAU-D13 TaxID=2714351 RepID=UPI0013FBE47E +-----DALVELEKKFDARLGVYAAGVG---TI-EHRADERFAFCSTFKGLAAAAVLHRNP +--MTHLDTVVTYTEADLMKSSTITRQHVQTGMKLRDLCDAAVRHSDGTAGNLLLRALGGP +AELTRYLRDLGDDETRMDRVEPDITSATPGDPRDTATPRSLGTDYQRLVLGDALEPAKRD +FLKDLLERSVTGAKRIRAGVPQGSKVASKTGTGSYGTANDIAVVWPPGREPILIAIMSSR +SSADAKYDEALIAEATAYVVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NEAU-LD23 TaxID=2486417 RepID=A0A3M8T018_9ACTN +--EITRQLRALEEEYAARLGVFAFDPATGATV-AYRAEERFPICSVFKALAAAAVLRDLD +RDGEFLAKRVHYTQEFVRKYAPVTGKNIEGGLTVEQLCAAAVSESDNAAANLLLSDLGGP +TAITRFCRSLGDGTTRLDRWEPELNTAEPWRDTDTTSPGAIGKTFARLVLGRALTPEDRE +RLTGWLVANTTNTERFRKGLPADWILADKTGGGQYGVANDVGVVWPPERTPLVLSVLSTK +YDPQGPTDNPLVARAAALVAD-- +>[subseq from] FRI family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001231866C +-----EEVRELETSFGGRIGVYILNPKNGKEF-AYRQDERFPLCSSFKAFLAASVLKRTQ +EKSVSLDDMVEYSGRVMEKHSPVSEKYRKTGASVQTLAKAAIQYSDNGASNLLMERIGGP +EGLTAFMRSTGDTDFRLDRWELELNTAIPGDERDTSTPKAVAMSLKNIAFGSVLDAKNKS +LLQEWLKGNTTGNARIRAAVPDKWVVGDKTGTCGYGTANDVAILWTDANSPAVMAVYTTR +PNQNDKHDEAVIKNAAKIAIK-- +>[subseq from] Beta-lactamase CARB-6 n=1 Tax=Vibrio cholerae TaxID=666 RepID=BLC6_VIBCL +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKTIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] class A beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010F57B07 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGACL-------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B5KFC7_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAVVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D75018C +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERA------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. IS-1742 TaxID=1772285 RepID=A0A101ALI7_9MYCO +-------VEALERANNAVIGVFAVDLDTGRTV-AHRAQESFAMCSTFKAYLAAQVLQLVG +RGERSLDQTLPVTAADVQPNSPRTEPRVGGEMTLAELCQAILQVSDNAAANILLRNVGGP +PAVTAFARGIGDPRSRLDRYEIELNAAVPGDPRDTSTPEALAGGFRAILTGDALAPPQRR +LLEDWMRANET--SSMRAGLPPGWTTADKTGSGDYGTTNDVGIAYGPQGQRLLLAVMTKT +ATPDAENMRPLVGEVTAAV---- +>[subseq from] Beta-lactamase Toho-1 n=2 Tax=Legionella lansingensis TaxID=45067 RepID=A0A0W0VF14_9GAMM +---IDKKLAELEASFGGRIGVYAINTANNTHL-QYRANERFPMGCTSKVIGVAAILKKSM +NDRTLLSQKVTYTKSDLTNWNPITEKHLADGMTVAELCAAAIRYSDNTAMNLLVRILGGV +EGMNAFARSIRDHSFRQDHWPTEAMSGGQGDLHDSSTPSAMANSLKRLALTNTLAKPQRE +LLLSWLKTNTTGDNRIRAGVPKGWTVGDKTGTGYYGTTNDIGIIWPPKCAPIVVAIYYTS +NDKKAVKREDIVAATIRILINEf +>[subseq from] Beta-lactamase n=1 Tax=Vibrio mediterranei TaxID=689 RepID=A0A3G4VEP8_9VIBR +--TLDESIASIEQRISGRIGVSVLDSRNQQQW-HYRGNERFPMMSTFKTLACAKMLHDAD +SGELDKNALAPITSDKLIPWSPVTEKMVGSSITVSKACEATMETSDNTAANIVLHSIGGP +QGLTEFLRLNQDDVTRLDRIEPELNQALSGDKRDTTTPNAMNTTLHRLLFEGALNQGSKN +QLMAWMQGNTVSDSLLRSVLPQGWSIADRSGAGANGSRGFTGAIWADNRKPLVISIYLTQ +TDLSMSERNQIINEIGGLIFQTy +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=A0A1A3AQV4_MYCFO +---IDDQLAELERRDNVLIGLYAANLQSGRTI-RHRPDEMFAMCSTFKGYAAARVLQMAE +RGEISLDNRMFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKAIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPGGQRLLLVMMTRS +QGPKAENLRPLIGELTALV---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodovulum sulfidophilum TaxID=35806 RepID=UPI00138A3AE6 +--TLADTVERVENRLGARVGVSLVDTGSGLSW-THRENERFLMNSTMKVPLCGAVLARRD +AGDLSLQTELPVRKSDLLAYAPVTEKRAGGEMTIAELCLAAIDMSDNTAANLLIAHLGGP +QAVTRFFRSAGDTISRLDRNEPELNTFNAADLRDTTTPAAMTETLRGLLLGDVLSRSSRG +QLAEWMSHGGVTGNLLRAEAPEGWVILDKSGSGTH-TRNLVALVTPVDGSPWIVTIFVSD +VDADSQTRNRALQDVGRAAM--- +>[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis excentricus TaxID=78587 RepID=A0A3G9G883_9CAUL +----GQRLMEIQKRHGGRVGVSVRDTAADGSL-NINSSQRFALCSTFKWVLAAAILKAVD +ENKLTVAQEIRYGKADLLDHSPVTEKHVAKGMTVGDLCSAAVAVSDNAAANLLLPLIGGP +AGLTAFVRGLGDTVTRLDRNEPELNSNIEGDERDTTTPDAMSSLLRTVFTGAVLQPQSLS +LLRDWMVATVTGPDMIPAGVPKGWTVGHKTGRGANGAVNDVAVIWPSDKPPLFLSIYTTG +GTLDDTGRNQIVSDITRLVID-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia terpenica TaxID=455432 RepID=A0A164PKR9_9NOCA +-----ASLAELERRYGARLGVFAVATGTGATL-AYRADDRFAMCSTFKGLAAAAVLSRNP +--LSHLDTRVSFTRDEIRSISPVTERHVDTGMTIGQLCDAAIRYSDGTAGNLLLDDIGGP +AALTAYLRTLGDPWSPMDNYEPELNRDAPGDERDTSTPRALATDYRTLVLGTALSPEKRG +LLTDWLLRSTTGTGRIRGAVPGSWQVAHKTGTGDYGRANDVAIIYPPSTPPLVLAIMSDI +SNYNAQPSDQLIAEAAT------ +>[subseq from] class A beta-lactamase n=1 Tax=Paenalcaligenes suwonensis TaxID=1202713 RepID=UPI0014075821 +-----QKAAAIEEQLQARVGVAVVDTGSGQSW-LYRADERFPMASTAKTLVCAALLQQGE +---PLLHSPILLQPDDIQTYAPVTKELVGQTLSAFQLCEITLRSSDNTAVNVVLKVLGGP +TAVTSFLRTIGDQSTRLDRMEPEVNEATPGDERDTTTPSAMAATMRALLLGSALNPTERE +QLVGWMKANEVAGPLLRAGVPSDWLVADRSGSAEYGTRGVAAVLWPAQHAPLVVAVYITE +TEAPIEARNAAIASLGQAIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium malmesburyense TaxID=1566886 RepID=UPI000B1A52A0 +---VADRLEAMERSQNALIGVFAVNLHTGRTV-AHRAQEPFAMCSTFKTYAAARVLQKAE +RGELALTDRVTIEEGDIVPNSPVTGAHVGQTMTLAELCQAALQQSDNAAGNWLLRTIGGP +SGVTGFARSIGDQRSRLDRWEVELNAAVPGDPRDTTTPEAIGGGYRSILTGNVLGEPQRR +RLEEWMRANQT--SSVRPVLPPGWTIADKTGSGDYASTNDVGIAFGPAGERLLLTIMTRT +PTPNAPNNRQLVGEVGSMLVA-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus maanshanensis TaxID=183556 RepID=A0A1H7TPN0_9NOCA +-qSLDATLDALEARYSTRIGVTAIDPASGRTY-RHRGEERFALCSTFKTYAAAEVLRRTV +TGASSLEEPVMVDPGDLVENSPVTEAAAGTAMTLRQLAEAALTRSDNTAGNYLLEEIGGP +PAVTALARDIGDESTRLDRWEPELNTALRGDPRDTSTPNGLAEGYRALIVGDALGSAERA +QLGDWMRASKTSDKRIRAELRPGWTAATKSGAGSFGTVNDAGVVWDPDGNPLVLAILTDS +LTADAQGNNQAVADTAAAVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5P4A0_9BACT +--DFANRILSIEKRIGARIGVAALDTGSSKRL-DYRSEERFPMCSTFKFLAAAAVLKRVD +GGQEKLDRFVSYGAKDILEYAPVTKAHLKDGMPLGALCAAAIEQSDNTAGNLLLDTIGGP +VGLTNFARSLGDQMTRLDRKEPELNGAIPGDERDTTTPASMQADLVRLLIGDALSQSSRH +QLEEWLQGNTTGASMIRAGVPPKWTVGDKTGRCGKGPTNDVGILRPPGRQRL-------- +----------------------- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio metschnikovii TaxID=28172 RepID=UPI0012AE7B19 +--RVEQEVRSIEEQLSARIGVAVFNTETGEHW-NYRGEERFPLTSTFKTIACAKLLHDSE +QGDIDPLSKVKIEENDLVTYSPIIEQYVGQEITLDDACQATMSTSDNTAANMIIKAVGGT +ESITSFIRAMGDEVTRLDRIEPDLNQGLVNDLRDTTTPNAMVITLHELLFGSVLSESSQQ +KLLTWMINNQVTDNLLRSVLPNGWGIGDRSGAGGFGARSITAIVWSKTQSPIIISIYIAQ +TEVSIEQRNQAIVKIGKAIFDNy +>[subseq from] Beta-lactamase class A n=1 Tax=Frondihabitans sp. PhB153 TaxID=2485191 RepID=A0A3N4V2L9_9MICO +--STRAAFAALENKYGARLGVFAVDTSSETTI-AYRPGERFAFASTYKALAAGILFKQST +--EDELDHTIHYTESDLVDYSPVTEKRVASGMTVREIIAAALQYSDNTAANLMLDQLGGP +AGLAESLRSLGDTTTRVDRPEPGVNEAIPKDPRDTTTPAAIAGDLRSFLLGGALATPRRS +EMTTLMLGNTTGAPWIRAGVPSTWKIADKTGNASYGTRNDIAVAYPPGRAPIVIALLSDR +GTVDATSDDGLLADATRVVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=UPI0013FE1C30 +--AAQAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPVCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP +QAVTSFAHESGDTVFRLDRWEPELNLAAPGDERDTSTPVAMVDTVQQLLLGDTLREPQRA +QLTEWMTGGARGTTGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAVRIAT--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=UPI000993460E +-----SELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIRYAQSDLMEWAPITSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEGQLN--VPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD +LLTDWLKRNTTGDQSIRAGVPTAWTVGDKTGSGFKGETNDIAVIWPTGRPPIVVAVLTVP +DDPKSTQGKPTIAEATRIALKAf +>[subseq from] Beta-lactamase n=1 Tax=Acidocella sp. MX-AZ02 TaxID=1214225 RepID=K5YKK0_9PROT +---ATSFLAESERRTGGRIGIYARNLATGRTL-SWRADERFVMCSTFKMSLVACVLSRVD +KGEERLGRFVQYGAAQLSNYAPVARLHLADGMTVGAMCQAAIEVSDNTCADLLLLSVGGP +AALTRFWRAEGDEVTRLDHTEPRLNFSPPGDPRDTTTPAAMAGDLQRFLLGDALSPASRA +RLTGWMLNCQTGGALLRAGLPKGWKVADKTGNNGKDALGDIAVAWPAPDRPIVICAYTQG +GQPKPEILPPILAGVGRMV---- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI0007E95753 +---IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYAAARVLQMAE +HGEISLDNRVFVDADALVPNSPVTETSAGAEMTLDELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS +QAHDP-KAEN------------- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia donostiensis TaxID=1538463 RepID=UPI00111C3B51 +--ELDIALAGIEERKHIRLGVIAHDPGRNLSY-IRRGEERFAMCSTFKVYAAAAILRLHT +QGRLTLDEPVPVAAADIVVNSPVTSAAQGRTLTLAQLCEASLTRSDNTAANLLLRRLGGP +AAITGFARSLGDTATRLDRWEPELNSAEPGDPRDTTTPTGLADGYRELLLGSGLPAAAKQ +TLTDWMRASVTSGERIRAGLPAGWTAADKTGGGSYGTVNDAGVVWSPDGAPLLLVLLTSS +TTPDAPNDNAALAETTAAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium novocastrense TaxID=59813 RepID=A0A100X4K3_9MYCO +---VEDRLGEMERRQNALIGVFATDLGTGRTI-AHRAHDMFAMCSTFKTYAAARVLQKAE +RGELALTDRVTIEPGDIVPNSPVTEAHVGQTMTLAQLCQAALQRSDNAAANWLLRVIGGP +SGVTDFARSIGDQRSRLDRWEIELNAAVPADPRDTTTPEAIGAGYRSILTGNVLAEPQRR +QLEDWMRTNQT--SSVRPVLPPGWATADKTGSGDYASTNDVGIAYGPAGERLLLAIMTRT +AAPDAPNDRQLVGDVASVLVA-- +>[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces sp. SAI-097 TaxID=2485145 RepID=A0A3N1DWM6_9ACTN +---SSRSLAALERSHQARLGVFAWNTVSGRII-RHREKELFPTCSVSKTPAVAAVLRDLD +QEGEYLRKVIRYGAADVDRYAPVTGENLANGMKVSDLCAAAITHSDNTAMNLMLKELGGP +TAVTRFCRSIGDTVTRLDRWEPELNSAEPGRMTDTTSPTAIGKTYARLVLMGTLGTADRD +RLKGWLLANTTGDNRLKAGLPTSWTVAEKTGTGEYGTTNDVGVAWNTRGEPVVLAVLSTK +THAEAPADESLLAEAAHVIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=unknown TaxID=N/A RepID=UPI0014388B2B +------ALFELEKKFDARLGVYAAGVG---TI-EHRADERFAFCSTFKGLAAAAVLHRNP +--MTHLDTVITYTEADLMKSSAITKQHVQTGMKLRDLCDAAVRFSDGTAGNLLLRDLGGP +AELTRYLRELGDNETRMDRVEPAITEATPGDPRDTATPRSLGTDYQRLVLGDALPPEKRD +FLKDLLERSVTGAKRIRAGVPQGSKVASKTGTGDYGTANDIAVVWPPGREPILIAIMSSR +SSADAKYDEALIAEATAYVVK-- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0011548006 +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +LALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRR +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0004822AB7 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTSFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMAGGARAATGIAAAVPPGWRVADKVGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PQADAAARADVVTSAARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Mycolicibacterium sp. 018/SC-01/001 TaxID=2592069 RepID=A0A552ZZP0_9MYCO +-----DRIAALARRYNARIGVYAADLGSDRSV-EVGADDMLAMCSTFKAYASAAVLQRAQ +QGRLALTDAVLVQRSDIRDHSPVTEPRVGSTMTLAELCQAALQQSDNAAGNLLLRTLGGP +PAITDFARSVGDDRTRLDRWETELNTAIPGDPRDTSTPRALGIGFRAVLTGDVLDSVHRQ +MLEDWMRANQT--SSMRAGLPQGWVTADKTGSGGYGTTNDVGIAYGPQGQRWLMSIMTRS +VTPDAESLRTLIGEIAAAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia terpenica TaxID=455432 RepID=A0A164NII6_9NOCA +-----ASLAELERRYGARLGVFAVATGTGATL-AYRADDRFAMCSTFKGLAAAAVLSRNP +--LSHLDTRVSFTRDEIRSISPVTERHVDTGMTIGQLCDAAIRYSDGTAGNLLLDDIGGP +AALTAYLRTLGDPWSPMDNYEPELNRDAPGDERDTSTPRALATDYRTLVLGTALSPEKRG +LLTDWLLRSTTGTGRIRGAVPGSWQVAHKTGTGDYGRANDVAIIYPPSTPPLVLAIMSDI +SNYNAQPSDQLIAEAAT------ +>[subseq from] class A beta-lactamase n=1 Tax=Lentzea albidocapillata TaxID=40571 RepID=UPI0004C3C5C6 +-----DALSELEKKFDARLGVYAMS-DNGSTI-EHRADERFAFCSTFKGLAAAAVLHRNP +--MSHLDTVVTYTEADLMKSSAITRQNVRTGMKLRDLCDAAVRYSDGTAGNLLLRDLGGP +AELTKYLRELGDTETRMDRVEPAITSATPGDPRDTATPRSLGTDYQRIVLGDALEPAKRD +FLTGLLERSVTGAKRVRAAVPAGSRVANKTGTGEHGTVNDIAVVWPPGREPVLIAIMSSK +SAADAKYDEALVAEAAAYVVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756C981 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAVAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANSVKGIRAGVPSDWRVAGKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADAAPRADVVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC401 TaxID=1848324 RepID=A0A5R8N8H7_9ACTN +--QVKKDLRSLEVSFKGRIGAYALDTATGKTV-TYRAGERFPMLSTFKAPLCAAVLRKAR +TKPGLMNRLIRWTAADMKPNSPVTEKHVKDGLTVSQLCEAAVTMSDGTASNLLLKQVGGP +KGLTRYFRTLKDATSRMDRWHPELNDWTPKDKRDTTTPAAIGRDLRVLTVGRALHAKDRR +QLLAWLLANKTGGERIRAGLPKSWTVADKTGTNSFGGGNDIAVVWPKKGAPVIMSIYTNR +TK-GLPTDNKTIAKTATILA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A2Z6A9H9_SHISO +------------------------------------------MMSTFKVLLCGAVLSRVD +AGQEQVGRRIHYSQNDKVEYSPVTEKHLTDGMTVRELCSAAISMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKVLTGELLTLASRQ +QLIDWMEADKVAGPLVRSALPAGWFIADKSGAGERGSRGIIGALGPDGKASRIVVIYTRG +SQATMDERNRQIAEIGASVI--- +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB35_STEMA +-----ADFAALEKASGSRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Actinomadura geliboluensis TaxID=882440 RepID=A0A5S4GF17_9ACTN +--EVTKQLTRLETTRRTRIGAYAIDTGSGRAV-GHRADETFPFASTFKAMACGAVLRKAR +QAPGLLDKVIRYTKDDLQEFSPVTEKHVDTGMTVAELCHATITQSDNTAGNLVLKEIGGP +AGLTAFLRSLGDTVSRSDRIEPGLNDWKPGEKRDTTAPRPWANDLRALTVGDALVPAERA +RLIDWLKATVTGDKRIRAGLPKSWTVGDKTGTGGYGSANDIAIAYPKGGAPLIIVVTTTR +KGAEADA---------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI0004D91200 +----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD +HDGSQLARVIRYTEADVTKHAPVTKDHIDTGMTIRDLCDATIRYSDNCAANLLLRELGGP +TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA +LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDRRPVLLTALTHK +PSPTAPGDTPLIIKLATV----- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium innocens TaxID=2341083 RepID=A0A498Q269_9MYCO +--DVRGRFAELEHRYAARLGVYVPASGTTAAI-AYRADERFAFCSTFKGLLVAAVLHQYP +--LSHLDTVVTYTGADIRSTSPITQQHVATGMSVGELCDAAIRYSDGTAANLLLADIGGT +SAFTGYLRSLGDSVSRLDQEEPELNRDPPGDERDTTTARAIALDYQQLVLGDALPVDKRA +MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPSGVPHVLAILSDR +AGYDAEPSEALVADAARCVAQ-- +>[subseq from] Class A beta-lactamase n=2 Tax=Streptomyces antibioticus TaxID=1890 RepID=A0A101QFD4_STRAT +--STPKGLRELEARHGARLGVFARNIATGRTV-RHRAAELFPMCSLFKTLASAAVLRDLD +RDGEFLSRRIHYTDADLPKGSDKTREHVADGMTVAELAEVAITFSDNGAGNLLLRELGGP +TAVTRFARSLGDRVTRLDRWETELNSAEPWRITDTTSPYAIGRTYGRLVLGDALDGPDRA +LLTHWLRSNTTSGTRLRAGLPTAWTVADKTGGGSYGTNNNVGIAWTEDGTPLLLAVLSTL +PEQDAVRDDVLIRDTAALLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Comamonas thiooxydans TaxID=363952 RepID=A0A0E3BGJ4_9BURK +--TLSDELAALEIQAQGRFGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ +RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVLVSDNTAANVLLEASGGP +AALTQWLRELGDGTTRLDRNEPSLNTALLGDERDTTTPQAMVQSLQKLLLGDVLEGYARA +LLQQWLVDSRTGDKRVRAGMPGDWTVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG +SPLDGAGREAVLARAGEAIK--- +>[subseq from] class A beta-lactamase n=1 Tax=Comamonadaceae bacterium CCH4-C5 TaxID=1768804 RepID=UPI00082BB94F +--TWNSAMEGIEQNAQGRLGVSMLDTETGLAL-GWRQDERFAMCSTFKLLLAGWMLSLVD +QGREKLDARVHYAPADVVDYSPVSGPRAGTGLTVSELCSATVSLSDNTAANVLLERHGGP +AALTRYLRMLGDPITRLDRNEPTLNEAAIGDVRDTTTPRPMLQTMQKLVLGESLSASSRA +WLQRWLIETSTGDKRLRAGAP-GWKVGDKTGTAGSGTANDVAVLWPPHRGAVLVTCYLTR +SAVAPEQRDAAIAAVGRAVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Sphaerisporangium album TaxID=509200 RepID=A0A367FST0_9ACTN +-----RLLRDLEKSSKGRIGAYAVDTATGRTI-GYRSGERFPLLSTFKALACAAVLDKAR +TTPGLMNRVIHWKSGDLKENSPVTEKHVDDGMTVAKLCEAAITYSDNTAANMVLRQIGGP +AGLTKYFRSLKDPITHLDRWETELNNWSLKEKRDTTTPAAIAHDLRKVTVDNALDPRDRA +QLNAWLRANTTGDARIRAALPKTWIIGDKTGSSSYGSANDIAVIHPTATPPIIMTIYTNH +HARDTAYDNKLIADTAAILTK-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia caribensis MBA4 TaxID=1323664 RepID=A0A0P0R7S6_9BURK +---ARERFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM +AERGLLDERVRYGDADLVANSPVTKRRVGEGMTIGELSAAALQHSDNTAANLLLTAVGGP +EVLNQFALSIGDEWFDLLRREPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLAPQQRE +QLKAWMLGNVTGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG +VMKQTLPRDEVVVEAARIVFD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea wenchangensis TaxID=568860 RepID=A0A1I0IUQ2_9ACTN +---VTKELRALEKSYKGRIGAYAIDTATGRTV-AYRSGERFPLLSTFKAPVCAAALHKAS +TAPGLMDKVVKWTKAELKPNSPTTEKHVADGLTVAQLCEAAITLSDNTAGNMVLKQVGGP +AGLTRYFRSLKDPVSRLDRWETELNDWSAKDKRDTTTPAAISRDLRLLTWGDALNAKDRQ +RLIGWLRANRTGDTRIRAGLPKSWTIGDKTGTNSIGGANDIAVVWPDKAAPIIMAVYTTR +STPS--VDDKVLAKTATVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Salmonella typhi TaxID=90370 RepID=Q8KPE0_SALTI +-rQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTIEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGS +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNKK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGRSIFDVy +>[subseq from] Beta-lactamase n=1 Tax=Rhodovulum sp. BSW8 TaxID=2259645 RepID=A0A366C1I8_9RHOB +-qALTDTISRLESALPARIGVAIRDSGSDWGW-GHRDSERFLMASTFKSVLCAAVLDRAD +RELLSLGDAVAIPPEAILDYAPVAETHVGGTMTLGDLCLATLDMSDNTAANLLIARLGGP +QEVTAFLRRIGDPVTRLDRTEPDLNLLDPADPRDTTSPAAMAATWQRLLLGDVLSPASRA +RLADWMSHGSVTASLIRASAPPDWTVSDKSGGGKDYTRNLVAMIQSPGRAPAIVAIYLSD +CPADWATRNAAVAEIGAAVI--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp8992 TaxID=2184554 RepID=A0A3N8IZY1_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIAQLCEAMLQAGDKGAGNLLMGVLGGP +QAVTSFARESGDTTFRLDHWEPELNKAAPDDERDTSTPVAMVDTLQRLLLGNALQAPQRT +QLTEWMAGGARGATGIAASVPPGWRVAEKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +QQADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium mageritense DSM 44476 = CIP 104973 TaxID=1209984 RepID=X5KT70_9MYCO +---LDGQISALEQRDNALIGIFATNLDNGRTV-TNRADDLFAMCSTFKGYAAGRILQQVG +RGQLSLDKRVFVDPGAVVANSPVTGPRAGSEMSLGELCQAALQQSDNTAANLLLRTMDGP +AGITAFARSIGDDRTRLDRWETELNSAIPGDPRDTSTPAALAAGYRRLLVEDALSPAQRG +QLEEWMRGNQT--SSLRAGLPAGWTTADKTGSGDYGSTNDVGVAYGPDGQRLVLAVMTRS +QADDADNLRPLIGELAA------ +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. JP2-270 TaxID=2217913 RepID=A0A2U9SU14_9BURK +--AAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAGAILARGA +LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIAQLCEAMLRSGDKGAGNLLMGVLGGP +QAVTSFARESGDTTFRLDHWEPELNKVAPNDERDTSTPVAMVDTLQRLLLGDTLHEPQRA +QLTEWMAGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPLVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Jiangella sp. KE2-3 TaxID=1623398 RepID=UPI000E356308 +----VAALTALEGDYDARLGVYAVDTGTGEIV-EHRADERFAFASTHKMLSAAAMLQATE +--TADLEQVIPIDAADLVGYSPVTEPAAGAGLTLLEIIDAAVTVSDNTAANLLFEQLGGP +DGLEAVVRGFGDETTSFDRIEPGLSDWVPGETRDTTTPRAMAANVQGLLLGDLLAEEDRT +LLHDTMRANTTGDELIRAGVPDGWVVADKTGSATHGGRNDVAVIEPPGAAPIVIAVYSNR +LDPEAESDPALIAAATEIVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI0009078ADF +--ALSAQVKSVEQTLGARVGVSVFIPSQGVAW-NYHGDQRFPMMSTFKTLACAKMLADVD +AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP +AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ +QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQDPMFVSIYLTQ +TEATFDERNAAIVTIGKSIFDTf +>[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobiaceae TaxID=41294 RepID=A0A1H4PMJ6_9BRAD +------ALAAYERDTGGRIGVYAENLSTGAKI-AWRAEQRFVMCSTFKASLAALMLARVD +RGEDRLEDMVAYGPKDILDYAPVAKQNLAHGMSVSDMCKAVVELSDNTCANLLLARAGGP +AALTAFWRSTGDTISRLDHNEPELNRSPPGNPHDTTTPSAMAGNLRRFLLGPVLTPPSRE +HLTEWMVGCKTGNNRLRGGLPGDWKVGDKTGNNGKDASGDIAIAWPKSGGPVLVCAYTQG +GSPTAPQFEAVFKEIGAMV---- +>[subseq from] Beta-lactamase n=1 Tax=Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5) TaxID=272568 RepID=B5ZHS4_GLUDA +-gDIQARLQELESRSGGRLGVAILDTATGRLI-GNRVNERFAMCSTCKALVVAFVLSRID +RNEEWLNRRVTFTEHDLVSPFKATKPHVGPGMTIAELCEAAITVSDSTAANLLFASFGGP +EALTTYLRSLGDQVTRLDHVELALNIVKPGEIHDTTSPAAMAETLRKLLLGNALSDASRA +LLAEWMSGTKDATHRLRAGLPAGWRIADKPGTWEKIATNDIGVVWPPGRAPIVVTAYLGE +APGLVASREAILADVARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=A0A0N9YFN9_MYCFO +---IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYVAARVLQMAE +HGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAVPGDPRDTSTPAALAVGYRAILAGDALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPGGQRLLLVMMTRS +QGPKAENLRPLIGELTALV---- +>[subseq from] Beta-lactamase n=2 Tax=Thalassotalea sp. ND16A TaxID=1535422 RepID=A0A099KCF7_9GAMM +-----KTIEDVKLKLGADVGVAVYDISSDDLW-SYNGDTRFPLMSTFKTLACAKLLVDID +NGEQSFDTSVVIKKASLVTWSPVTEKHVGEKFSLRQACSATMIMSDNTAANIVLNGINGP +TALTQFMRSIGDPITRLDRVEPYLGEALAGDVRDTTTPNAMVKSLHKLLFGNALSAANKT +QLKQWMTDNKVSDSLLRSVLPVGWTIADRSGAGGYGSRGITAVVWSEQHSPLIVAIYLTQ +TEASFAQRNKAIAQIGKEIFSYy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia seminalis TaxID=488731 RepID=UPI000F5B21D0 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEVVSGSPITESRVDTGMTIVQLCEAMLQAGDKGAGNLLMGVLGGP +QAVTSFARESGDTTFRLDHWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLHEPQRT +QLTEWMAGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +QRADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Lentzea jiangxiensis TaxID=641025 RepID=A0A1H0I9Z3_9PSEU +------ALFELEKKYDARLGVYAMS-DTGRTI-EHRADERFAFCSTFKGLAAAAVLHRNP +--MAHLDTVVTYTEADLMKSSAITQRNVGTGMKLRDLCDAAVRHSDGTAGNLLLRDLGGP +AELTGYLRELGDTETRMDRVEPDITSAVPGDPRDTATPRSLGTDYQRLVLGDALPRDKRD +FLNDLLERSVTGARRVRAGVPAGSRVASKTGTGSYGTVNDIAVVWPPGREPLLIAVMSSK +RAADANYDEALVAEAAAYVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium austroafricanum TaxID=39687 RepID=A0A2S8KTZ3_MYCAO +---LDQRIEALGQRHNAQIGLYALDLDTQRGI-EFGADEPFAMCSTFKAYAAAAVLQRTQ +TGELTLNDAIPIEPGDIRPHSPVTEPRVGTSMSLAELCQAALQQSDNAAANGLLRVLGGP +QAITAFARSIGDHRTRLDRWEVELNSALPGDPRDTSTPRALGDGYRNILTGDVLNPPTRQ +QLLDWMLANQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVAYGPAGQQVLLSLMTRS +AVPDAPSLRPLIGELAALVLS-- +>[subseq from] class A beta-lactamase n=1 Tax=Azospirillum sp. B506 TaxID=137721 RepID=UPI00034C570C +--SIEARLKELEIRSGGRLGVAVLNVATGRLV-GHRIDERFAMCSTVKALVAAFVLARVD +RGEERLDRRVVFTERDLVPPSKATKPHVGPEMTIAELCEAAVTVSDSTAANLLLASFGGP +AALTTYLRSLGDPVTRLDRIELDLNIVKPGDLRDTTTPGAMAETLRRLLLGNALSHASRI +RLTTWMVEAKDAAQRLRLGLPAGWRIANKPGTWEGISTNDIGVIWPPHGGPIIVTAYLGE +APGSIGIQEKILSDVARIVV--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas acidaminiphila TaxID=128780 RepID=A0A0S1AXK9_9GAMM +-----AGFAALEAESGGRLGVCLWHPASGARF-GQRMDERFPMCSTFKFLLAAAVLERAG +RGALSLDQRVPVRAADLLGNSPVTARHVGKDLGVRDLCRATLTTSDNAAANLLLPLVGGP +AGLTAFLRAQGDAVTLAARYEPDANRFAADDPRDTTSPAAMAGNLQRFVLGDALALAGRR +QLADWLIDNETGDARLRAGLPPGWRVGDKTGSNGRDTSNDIAVLWPRGGTPWVLAAFLQG +SALDDAGRDGILRRVGERAAA-- +>[subseq from] Beta-lactamase n=1 Tax=Halomonadaceae bacterium TaxID=2026746 RepID=A0A2E2BL67_9GAMM +--DLDQRLAELERAADDRVGVALMNVTTGAVA-SHRGDERFLFNSTGKFFIAAAVLARVD +EGSETLDRRIVVEKGDLVGWTPITEKRLGEPLTVAELCQAAVAWSDNAAANALIDSVGGH +EAVTAFLRAIGDDTTRLDRIEPDLNTDHEGDERDTTTPLAMMTTLRTLLLGDALSPSSRH +QLAAWMIEGKVGDARLRAGMPSSWLVGEKTGTNGVGNASDIGIGWPGDRGAVIAVAYTLM +PSATKTQRDETIAAVGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium austroafricanum TaxID=39687 RepID=UPI00056BF22F +---VEQRLDALGRRHNAQIGLYAIDLNTQKSL-AYRDTESFAMCSTFKAYAAAAVLQRTQ +TGELTLNDAVPIEPGDIRPHSPVTEPRVGTSMSLAELCQAALQQSDNAAANGLLRVLGGP +QAITAFARSIGDHRTRLDRWEVELNSALPGDPRDTSTPRALGDGYRNILTGDVLNPPTRQ +QLLDWMLANQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVAYGPAGQQVLLSLMTRS +AVPDAPSLRPLIGELAALVLS-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SHY8_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSG----------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. AA8 TaxID=2720021 RepID=UPI00143B7D7E +--RISRQLRALEREHSARLGVFARNMVTGKTV-VHRPDERFPMCSTFKTLAVAAVLRDLD +HDGTFLAKRIHYTAEYAKAYDKITGKNVANGMTVEELCGAAISYSDNAAANLLLTELGGP +TAVTRFCRSVGDGTTRLDRWEPDLNSAEPDRITDTTTPRAIGRTYAQLVLGNALDAADRK +RLTGWLLANTTSDQKFRAGFK-GWTVADKTGSGSYGTSNDVGVVRTPEKAPVVVSVLTTK +HEPKAAGDDALVRKAAELLA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. TaxID=391 RepID=A0A5C7TU25_RHISP +---GEAQLAALESRHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALVAAFILARVD +KGEEELDRRIHYGKRDIIGGSAATKIHAGNAMTISELCAAAVTLSDNTAANLLLSSFGGP +KALTAFCRRLGDEITRLDRIEPALNYDKPDDLRDTTTAAAMLENLRRLLFTDVLSPASRS +QLAAWLITTKTGDSRLRTGLPRDWLAGDKTGTNGAGNANDIAVLWPSNRAPIIVTAYCEI +PAIAAGERDAVIATIGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=A0A087NWY3_BURPY +--AAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAGAILARGA +LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIAQLCDAMLRSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTTFRLDHWEPELNKAVPDDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPLVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=2 Tax=Nocardioides sp. SLBN-169 TaxID=1571486 RepID=A0A542T2E7_9ACTN +------SIAALEQKHQRHLGVWAKNMRTGRVI-EHRADERFPMLSTFKTLLAASILRDHP +--ARTLQQRLTWEPADVVVNSPVTSLTTRNGLTVAQLAEATMTRSDNTAANELLHLIGGP +SGITRFARSLGDTVTRLDRWEPDLNSAIPGDPRDTTSPRAIAQTYTKLVLGDALDRADRD +QLTTWMLANQSTVTRFGAGVPAGWRLADKTGGGDYASRNDVGVTWTPDGAPIVIAALTRS +DDPAATPLDTPLADIAATVC--- +>[subseq from] class A beta-lactamase n=1 Tax=Fertoebacter nigrum TaxID=2656921 RepID=UPI00128B9806 +--QLMQTVDSIEQSLNVRVGLVVRDSASDWAI-SHRADERFLMTSTFKAMLCGAVLDRVD +DGALDLGETIKIEAEAILDYAPVTEGRVGDTMTVADLCLAALDMSDNTATNLLIDRLGGP +QSVTDFLRKIGDPVSRLDRREPELNTFAVGDLRDTTTPDAMVATWQAMLTGDALSSTSRA +QLVDWMSAGGVTGALIRASTPDGWQVADRSGSGNF-NRNIVAMVKPPGRAPYFIAIFLSD +AELDFETRNAAVIDLSRAVMD-- +>[subseq from] class A beta-lactamase n=1 Tax=Lentzea jiangxiensis TaxID=641025 RepID=UPI000B7DE6C7 +------ALFELEKKYDARLGVYAMS-DTGRTI-EHRADERFAFCSTFKGLAAAAVLHRNP +--MAHLDTVVTYTEADLMKSSAITQRNVGTGMKLRDLCDAAVRHSDGTAGNLLLRDLGGP +AELTGYLRELGDTETRMDRVEPDITSAVPGDPRDTATPRSLGTDYQRLVLGDALPRDKRD +FLNDLLERSVTGARRVRAGVPAGSRVASKTGTGSYGTVNDIAVVWPPGREPLLIAVMSSK +RAADANYDEALVAEAAAYVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Colwellia sp. 39_35_sub15_T18 TaxID=1856279 RepID=A0A1Y5D2Y1_9GAMM +---IIKKIEEQEHQLSARIGVSIYDVAANKLW-SYNGNTRFPLMSTFKVLACAKLLADVE +KGLQSFDTSTVITENSLITWSPITKNLVGEKMSLKQACSAAMIMSDNTAANIVLNGIKGP +KALTQFMRSIGDEVTRLDRIEPDLNEALDGDKRDTTTANAMVKSLHTLLFGDVLSQASKT +QLKQWMIDNKITGSLLRSVLPENWSIADRSGSGGYGSRGITAVVWSDKRTPLVISIYLTQ +TEASFTQRNKAIAIIGKEIFTVy +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis niigatensis TaxID=369932 RepID=A0A2N3WQ83_9PSEU +----QPDFAALEKAFDARLGVDAIDTGDGREV-AYHADDRFAYASTHKVFNAAAILHRGD +----DLTRTVTIRQSDLVPNSPITEKHIGEQISLQSVLDAALRYSDNTADNLMFREIGGP +AGLAAEVRRLGDTVTHVDRIEPALNETSPGDVRDTTTPRVWAKDLRAVALDSGLPADKQA +VLTKIMRANTTGAHVIRAGVPADWQVADKTGTADYATRNDIAVLWPPHRAPIVLAVLSDR +AHKDAKTDDNLIAQAAAAVVK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. HI2761 TaxID=2015360 RepID=A0A228Q8W5_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPQCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGEVLHEPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAVLWPPSRAPIVMAVSFTQ +PDAAAAARADVVTAAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. WAY2 TaxID=2663121 RepID=UPI00131FCE32 +---LDSRIAELEARHSTRIGVTAVDPTTGAVY-RHRGAERFALCSTFKTYAAAEVLRRTS +EGTSSLDKAVPVEASALVENSPVTAAAVGTSMTLAELAEAALTRSDNTAGNLLLTEIGGP +QAITALARSIGDDTTRLDRWETELNTALRGDPRDTSTTDGLAEGYRALLLGDELEPTHRR +QLLDWLRASTTSDTRIRAGLPPGWSAADKTGTGRFGTANDAGVVWDREGNPLVLVILTDT +STEAAQPNSDAIAETTTAVI--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis antarctica TaxID=1854586 RepID=A0A263D0W0_9PSEU +---------GLEREFDARLGVYAVDTGTGREL-AFHADDRFAFASTVKALAAGVTLQRNT +--LGELEERVRFGPGDLVPHSPVSERHVDTGMTLREAMDAALRYSDNTALNLLLPEIGGP +DGLTAALRGIGDATSRSDRTETELNETAPGDPRDTSTPRALAGSLRAFALGDTLPEDKRA +VLTELLRTNTTGETLIAAGAPDGWVVGDKSGAADHGTRNDIAVLWPPDRAPVVMAVMSDR +RAEDAEYEDALVARAATAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. YIM 130001 TaxID=2259644 RepID=A0A399GL58_9ACTN +--ELGRQLGELEERYAARLGVFARNMATGRTV-RHRADERFPMCSVFKTLAAAAVLRDLD +--DSHLGRRIHYTQGDVDKYAPVTGKNIAGGLTVRELCAAAVSESDNAAANLLLRDLGGP +RAITRFCRSLGDGVTRLDRWEPELNSAEPWRRTDTTSPRAVGTTYARLILGRALDVPDRA +KLTGWLVANTTNMERFRAGLPDDWILADKTGGGEYGVANDVGVVHPPHGAPLVLSVLSTK +LDPAGPTDNPLVAEAARLVAAH- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium kansasii TaxID=1768 RepID=A0A163UDZ7_MYCKA +--DVQGRFAELEHRYAARLGVYVPASGTTAAI-AYRADERFAFCSTFKGLLVAAVLHQYP +--LSHLDKVLTYTCADIRSTSPITQQHVATGMSIGELCDAAIRYSDGTAANLLLADIGGT +TAFTGYLRSLGDSVSRLDQEEPELNRDPPGDERDTTTAHAIALDYQQLVLGDALPADKRA +MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPSGVPHVVAILSDR +AGYDAEPSEALVADAARCVAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5755 TaxID=1519475 RepID=A0A0M9XUR9_9ACTN +----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD +HDGSQLSRVIHYTEAEVTKHAPVTKDHIDTGMTIRDLCDATIRYSDNCAGNLLLRELGGP +TAITRFCRSLGDPVTRLDRWEPELNSAEPDRRTDTTSPYAIARTYQRLVLGNALDRPDRA +LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDGAPVLLTALTHK +PTPTAPGDTPLIIKLATV----- +>[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces sp. 1121.2 TaxID=1938831 RepID=A0A2G6ZUA1_9ACTN +------RLSDLEQEYSARLGIFAHDTGTGRTV-AYRADEHFPICSVFKTLAVSAVLRDLD +RDGEYLARRIRYTAKYVTDYAPVTEENVAAGMTVEELCAAAVSQSDNGAANLLMRELGGP +TAITRFARSVGDATTRLDRWEPELNTAEPWRTTDITSPREIGRTYARLVLGRALPTQDRT +RLTGWLIANTTNTERFRAGLPAGWVLADKTGGGSYGVANDVGVVWPPGRPPLVLAVLSTK +YAPEGPTDNPLVSRAAALVADE- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB40_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR +QFADWLIDNQTGDACLRAGLGKRWWVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio mediterranei TaxID=689 RepID=UPI0007854414 +--TLDESIASIEQRISGRIGVSVLDSSNQQQW-HYRGNERFPMMSTFKTLACAKMLHDAD +SGELDKNALAPITSDKLIPWSPVTEKMVGSSITVSKACEATMETSDNTAANIVLHSIGGP +QGLTEFLRLNQDDVTRLDRIEPELNQALSGDKRDTTTPNAMNTTLHRLLFKGALNQGSKN +QLMAWMQGNTVSDSLLRSVLPQGWSIADRSGAGANGSRGFTGAIWADNRKPLVISIYLTQ +TDLSMSKRNQIINEIGGLIFETy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces azureus TaxID=146537 RepID=A0A0K8PXP2_STRAJ +------RLADLEREYGARVGVYALATGTGATA-VHRSDERFAFCSVFKALAAAAVLHHRS +--LDGLDRRVTYTRADLKSTTPITGRHVATGMTLRQLCDAAVRYSDGAAGNLLMRDLGGP +AKLTAYLRGLGDTVSRMDHYEPELHDVPPEDPSDTTTPRAIATDFHKLLLGTALPAGERA +LLTDWLSRNATGARRIRAGLPKGWQVADKTGTGNYGRANDIAIVRPTRTEPLVLAVMTDR +RGYDAAPSDALIAEATAR----- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. CB01201 TaxID=2020324 RepID=A0A2M9JD36_9ACTN +--DVADTLRQLEASHDVRIGAYALDTGTGRTV-SYRGNESFPSLSTFKAMACAAVLDRAR +YEPGLLGKVVHWKASDEVANSPVTKGQGDKGMTVAELCRAAITRSDNTAGNMVLHQIGGP +QGMTRYYRSLGDPVSRLDRWEPELNDWRPGERRDTTAPAAMGRDLARTSLGCGLVPADRD +TLNTWLRGTVTGDERIRAGLPKDWTVGDKTGTTDYGSANDIAVAWPKSGHPVIIAIYTNH +AAAEAPADNAVIASTASALV--- +>[subseq from] Beta-lactamase n=1 Tax=Thalassotalea sp. 42_200_T64 TaxID=1856287 RepID=A0A1Y5GI18_9GAMM +--SMVKTIEEVKQKLGADVGVSVYDVSSDDLW-HYNGDTRFPLMSTFKTLACAKLLADIH +NGEQSFDTSVVIKKESLVTWSPVTEKHVGESFSLRQACSAAMIMSDNTAANIVLKGINGP +TALTQFMRSIGDKITRLDRIEPYLGEALDGDVRDTTTPNAMVKSLRELLFGNTLPAASKT +QLKQWMTDNKVSDSLLRSVLPIGWLIADRSGAGGYGSRGITAVVWSEQRSPLIVAIYLTQ +TDASFAQRNKAIAQIGKEIFTFy +>[subseq from] IMI-5 beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A125S6J9_ENTCL +-----DEIKNLEKKFNGRIGVYALDTGSGKSF-AYRANERFPLCSSFKGFLAASVLKGSQ +DKQLNFSEIVNYNTRSLEPNSPITAKYKEQGMPLGEMAAAALQYSDNAATNIILERIGGP +VGMTKFMRSIGDEEFRLDRYELDLNTAIPGDERDTSTPEAVGKSLKNLALGNILNDSEKE +TYQTWLKGNTTGAARIRSSVPREWVVGDKTGTCGYGTANDYAVVWPDDRAPLIISVYTTK +YEKDAKHEEEFIAEASRIAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075354F6 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA +LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLSEAMLQFGDKSAANLLMSVLGGP +QTVTEFARASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDMLGAPGRA +QLTKWLLGSANGVAGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADAAPRADVIAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 1164985.4 TaxID=1834069 RepID=A0A1A3T6C3_9MYCO +--QLADRLGEMERNHNALIGVFAVNLDTGRTV-AHRPRDPFAMCSTFKTYAAARVLQGAE +RGELALTDRVPVAQSDIVPNSPVTGEHVGQTMTLAELCQAALQQSDNAAGNLLLRTIGGP +SGVTDFARSIGDQRTRLDRWEIELNAAVPGDPRDTTTPEALGGGYRSLITGNVLGEPQRR +QLDDWMRANRT--SSVRPVLPPGWTIADKTGSGDYASTNDVGVAFGPAGERLLLAIMTRT +AAPDVPNDRRMVGDVGSMLV--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=A0A1A2FVW7_MYCFO +---IDDQLAELERRDNVLIGLYAANLQSGRTI-RHRPDEMFAMCSTFKGYAAARVLQMAE +RGEISLDNRMFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAVPGDPRDTSTPAALAVGYRAILAGDALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPGGQRLLLVMMTRS +QGPKAENLRPLIGELTALV---- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI00096D267B +---IDDQLAELERRDNVLIGLYAANLQSGRTI-RHRPDEMFAMCSTFKGYAAARVLQMAE +RGEISLDNRMFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAVPGDPRDTSTPAALAVGYRAILAGDALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPGGQRLLLVMMTRS +QGPKAENLRPLIGELTALV---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Aquabacterium sp. TaxID=1872578 RepID=A0A5C8BJH1_9BURK +--------EGIEHNAQGRLGVSMLDTETGLAL-GWRQDERFAMCSTFKLLLAGWMLSLVD +QGREKLDARVHYAPADVVDYSPVSGPRAGTGLTVGELCSATVSLSDNTAANVLLERHGGP +AALTRYLRALGDPITRLDRNEPTLNEAAIGDVRDTTTPLAMLQTMQKLVLGESLSASSRA +WLQRWLIETSTGDKRLRAGAP-GWKVGDKTGTAGSGTANDVAVLWPPHRGAVLVTCYLTR +SAVAPEQRDAAIAAVGRAVVS-- +>[subseq from] Beta-lactamase class A n=1 Tax=Lechevalieria xinjiangensis TaxID=402600 RepID=A0A1H9M5K7_9PSEU +-----DALAELERKFGARLGVYAT--GAGGTV-EHRADERFAFCSTFKGLATAAVLHRNP +--MSHLDTVVTYTEAELMKSSAITRQHVRTGMKLRDLCDAAVRYSDGTAGNLLLRDVGGP +AELTRYLRELGDTETRMDRVEPDITSATPGDPRDTATPRSLGTDYRRLVLGDALPPEKRD +FLTDLLERSVTGAKRVRAGVPQGSRVASKTGTGSYGTVNDIAIVWPPGGEPLLIAVMSSK +DAADAGYDEALVAEAAAYVVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI0012621F4E +--ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD +AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP +AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINNTLNTLVLGETLSSASRQ +QLKTWMQDNKVADVLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ +TEATFDERNAAIVTIGKSIFDTf +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderiaceae bacterium TaxID=2030806 RepID=A0A522S8B4_9BURK +---LDGAVTQAELALRARIGVALIDTASGTVW-QRRGGERFPLNSTHKVFSCAAALARAD +RHEADMDAGIPIDTTTLVAYSPVTAKVPAGGMSLRQLCRAAVSFSDNTAANLVAGAIGGP +TAVTAFLRAIGDGTTRLDRLEPELNQATPGDVRDTTTPLAAAESLQSLLLGDALSRPARA +ELRQWMLNDRVADALLRSGLPKDWRVADKSGAGGHGSRAIIAVAWPSERPPVVIAIYITQ +TDASMAARNHAIAHIGSALATAf +>[subseq from] Beta-lactamase n=1 Tax=Nesterenkonia salmonea TaxID=1804987 RepID=A0A5R9BIB6_9MICC +--TVSESFKELESRYDARLGVYAVDTGSGEEV-TWRDDERFAYTSTIKAIAAGALLDQVG +--LDGLETEVPIQTGDMVPHAPVTENHIGQTLTLAELTEAAVTVSDNPAANYLFDELGGP +AEFDAVLEDLGDDVTEVVRREPELNEATPGDDRDTTTPRAISENLREYLFGTTLSDEEKS +QLRQWMIDSETGDALIRANLPSEWTIGDKSGNGGYASRGNIAAIWPPEGDPIVIAVLSSR +DEPDAEHDDRLIAEAAEVAVS-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium rosettiformans W3 TaxID=538378 RepID=A0A4S8QAH6_9RHIZ +---IVASAKRVEQKLDMRVGFTVIDTGDGTVT-GYRQNERFAMASTFKAFACAAALSRGE +---AVLAKKTTIRQADLRPYSPVTERRVGTSISTRALCEMTLRTSDNAAANAILKALGGP +AEVTGFLRQIGDETTRLDRYEPELNEAKPGDPRDTTTPQAMAETLRRLLLQDVLEPQARD +QLEEWMAGNAVAGGLLRSRLPEGWQIADRSGAGGHGTRGVIALVRPPQGAPLIVAIYMDR +TDHPLKVRDAAIAEIGAAIFETy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. HI2500 TaxID=2015358 RepID=UPI000B7A70C3 +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAILARGS +LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFVRASGDTSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGDTLQEPQRA +RLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio alginolyticus 40B TaxID=674977 RepID=D0WWU8_VIBAL +-sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNAMLNTLRTLVEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLVAQISQLILQKy +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A4Q2ADU8_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARESGDTAFRLDRWEPELNLAAPGDERDTSTPVAMVDMLQRLLLGDTLHEPQRT +QLTEWMTGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPLVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=3 Tax=Gammaproteobacteria TaxID=1236 RepID=W0TY33_PSEAI +-rQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGS +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNKK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGRSIFDVy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFF6AA6 +--RAQAELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMDVLGGP +QAVTAFARESGDTTFRLDRWEPELNAVGPGDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSLTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFB19A +--RAQAELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMDVLGGP +QAVTAFARESGDTTFRLDRWEPELNAVGPGDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Herbidospora cretacea TaxID=28444 RepID=UPI0004C306A3 +-----ADLRALETSFKGRIGVYALDTATGRTV-AYRSGERFPLASTFKGVLAAAVLDKKP +---DILGKRILIRKKDLLPNSPETQKHVGSRMTVAALARAAVTKSDNAAANLLLRQIGGP +KGLTRYFRGLDDHVSRLDRNEPGLNLWHPREVRDTTTPAAIAADLKALTVGGALDAGDRR +TFTGWLVANETGDNRIRAGLPKSWRIGDKTGTGGYGTANDYAVIWPKGSKPIIMAIYTNR +TDRNAAADESVIARAATIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides TaxID=670516 RepID=UPI0004AA4337 +-----SELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYAQSDLMEWAPITSQHVAEGMTVSGLCDATLRYSDNTGANLLIAQLGGP +KQTEKFVRSLGDNVSRMDRTEDQLN--VPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD +LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP +DDPKSTQGKPTIAAATRIALKAf +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI0010FE1535 +--ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KDKSVLTHSVVIKKSDLVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHDPMVVSIYIQQ +SSASMDERNKAIATIGKQVFTYf +>[subseq from] FRI family carbapenem-hydrolyzing class A beta-lactamase n=6 Tax=Enterobacteriaceae TaxID=543 RepID=UPI000F04DCE3 +-----EEMRELETSFGGRIGVYILNPKNGKEF-AYRQDERFPLCSSFKAFLAASVLKRTQ +EKSVSLDDMVEYSGRVMEKHSPVSEKYRKTGASVQTLAKAAIQYSDNGASNLLMERIGGP +EGLTAFMRSTGDTDFRLDRWELELNTAIPGDERDTSTPKAVAMSLKNIAFGSVLDAKNKS +LLQEWLKGNTTGNARIRAAVPDKWVVGDKTGTCGYGTANDVAILWTDANSPAVMAVYTTR +PNQNDKHDEAVIKNAAKIAIK-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured Desulfovibrio sp. TaxID=167968 RepID=A0A212J2R0_9DELT +-kNLQKMLAELEASSGGRLGVAASVSNGDKIL-SYRGNERFPMCSTFKVLAAAAVLRDKT +---NILEQRIHFAKSDIQPWSPVTEKHLEDGMTVSELCKAMLQHSDNTAANLVLAQLGGP +AGLTSIARSFGDTTFRLDRWEVELNTAIPGDARDTTTPLAMRRTLNGLLCGNQLKAPARK +QLTDWMLGCATGAGRIPAGAPQGWRSAHKSGSGENGTANDVGVLLPPQNKPLTVALYLTG +SRLTGPENDKILAQATRLVC--- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. UCD-KPL2560 TaxID=1885315 RepID=UPI0008247703 +---TGQAFAALEARAGARVGVVALDTGDGHAI-GYRADERFAFASTNKVFIAAAVLDAAT +--GSDLDEVVHYDRGDLLSYAPVTRPAVDTGLTVRQLVDAAVRSSDNTAANLLVERLGGV +DAVARWLRSTGDDVTDVSRTEPDLNTAVPGDRRDTTTPAQSATDLRAVLLGDVLDADDRA +LLLGSMRGTTTGDGTIRAGVDPAWTVADKTGTASYGVRNDIAVVTPPGRDAIVLVVMTSH +PASDAEPSDALVAEVTRTAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010F6514C +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAC--------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. ACS1612 TaxID=1834117 RepID=A0A1A1YZC2_9MYCO +---VADRIAALERRHNAYIGVFAVDLGGGRSF-SHRGQQPFAMCSTFKAYAAGRVLQMVE +QGQLTLDQQVFVDPAGVVANSPRTEPRAGGNMTLDELCQAALQVSDNTAGNLLLNTIGGP +PAVTAFARSIGDQGSRLDRWETELNSAVPGDPRDTSTPEALGGGYRALLTGDALAPAQRQ +QLEDWMRANET--SSMRAGLPQGWTSADKTGSGDYGTANDVGVAYGPEGQ-LLLAVMTRS +QLSDAASLRPMIGEVTALL---- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI0010FE94C1 +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKTIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] Beta-lactamase class C n=2 Tax=Burkholderia TaxID=32008 RepID=A0A318J0R0_BURPY +--AAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAGAILARGA +LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIAQLCEAMLRSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTTFRLDHWEPELNKAVPDDERDTSTPVAMIDTLQRLLLGDTLREPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPLVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium goodii TaxID=134601 RepID=A0A0K0XBN6_MYCGD +-------IVDLEQRHNAVIGAYAVNLDSNRTV-AHRADDSFAMCSTFKAYLAARVLQGAQ +RGELSLDDRVFVDPSVLLPNSPITEEHAGGELTLAELCQAALQRSDNAAANLLLNQIGGP +PAVTEFARSIGDQRTRLDRWEVELNSAVPADPRDTSTPAALAGGFRAFLTGDVLNPPQRQ +LLDEWMRANQT--SSMRAGLPDGWTSADKTGSGDYGSTNDVGIAYGPQGQRILLALMVRS +GGDDAAGFRPLIGELTAMV---- +>[subseq from] Beta-lactamase n=1 Tax=Pseudoalteromonas citrea TaxID=43655 RepID=A0A5S3XLG9_9GAMM +--NISKKIEEIESQLDARIGVSIYDVTGNKLW-NYNGDTRFPLMSTFKTLACAKLLVDVE +EGLQSFNTSSVITKSSLVKWSPVTKKHVGKQFTLKQACSAAMIMSDNTATNIVLAGIKGP +KELTHFMRSIGDNVTRLDRVEPFLNEALDGDKRDTTTPTAMVKSLHTLLFGDVLSQDSKV +QLKQWMIDNKVTGSLFRSVLPEGWSIADRSGAGGYGSRGITAVVWSDKRSPLIISIYLTQ +TDASFALRNKAIASIGKEIFTVy +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium iranicum TaxID=912594 RepID=A0A1X1WCA5_9MYCO +---VEERIEALAKRHNAQIGLYTVNLDSEESL-GYRDTEVFAMCSTFKAYAAAAVLQRAQ +QGRLALSDTVPIEPADIRPHSPVTEPRVGTAMTLAELCQAALQQSDNAAANGLLRALGGP +PAITEFARSIGDDRSRLDRWEVELNSAVPGDPRDTSTPRALGAGYRAILTGDVLQPAGRQ +QLVDWMLGNQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVVYGPAGQRMLLAFMTRS +AVPDAASLRPLIGELATLVMA-- +>[subseq from] Beta-lactamase n=1 Tax=Jiangella alba TaxID=561176 RepID=A0A1H5KDF8_9ACTN +------AVRELERAHDVTLGVSATNLATGTRL-AHRSGDRFPILSVFKSIAAAAVLRDLD +--ESRLEHRVWYPPADILLNSAITAEHVDTGMTVAELCDAAIRFSDNAAGNLLLREIGGP +RGLTAFARSTGDDATRLDRWEIELNTAEPGDVRDTSTPAALARTFAGLLVGDLLRPRDRR +RLRDWMLANTTSGPRFRDALPDGWRLADKTGAGDYGANNDAGVAWNPAGQPIVIVAMSRR +AERDAPRVDAALADVARLVVR-- +>[subseq from] Beta-lactamase n=2 Tax=Comamonas TaxID=283 RepID=A0A096FI94_COMTE +--TLSDELAVLEIQAQGRFGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ +RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVLVSDNTAANVLLEASGGP +AALTQWLRELGDGTTRLDRNEPSLNTALAGDERDTTTPQAMLQSLQKLLLGDVLEGYARA +LLQQWLVDSRTGDKRVRAGMPGDWTVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG +SQLDGAGREAVLARAGEAVKR-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces bottropensis ATCC 25435 TaxID=1054862 RepID=M3EKI1_9ACTN +---LAGRLGELEREYSARLGVFAHDTATGRTV-AYRADERFPLCSVFKTLAAGAVLRDLD +RDGEYLARRIRYTEEYVKAYCPVTGENVSAGMTVGELCAATVSHSDNGAGNLLLRELGGP +TAITRFCRSLGDRTTRLDRWEPELNTAEPWRTTDTTTPRAIGGTYARLLLGRALPDADRD +LLTGWLVANSTNVERFRAGLPADWTLADKTGGGSYGVANDVGVVRPPGRPPLVLSVLSTK +YDPEGPTDNPLVARAAGLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI00130289F9 +--ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KDKSVLTRPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHDPMVVSIYIQQ +SSASMDERNKAIATIGKQVFTYf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. AX6 TaxID=2653171 RepID=A0A654D3S6_9SPHN +-----AELAAIAAEVGGRLGVHAFDTTTSAAI-GIDAGSRYAMCSTFKAPLAAAILTQVD +AGTLHLDQSVRFTRADLVPYAPVVEAALDRGLSVEALCKGAVEISDNVAANLLLALIGGP +AGFTRFVRARGDAVTRLDRIEPELNLVRGGDVRDTTTPAAMVGLMGAVLTGKLLTPASRD +RLIGWMVASPTGRERLRSGFPADWRAGDKTGTSGEGYFNDIAIMWPPDRAPILVACYLDA +PGLDPEAANAAHAKVGALIARRf +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI00084D317B +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSIFKTIACAKLLYDAE +HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. A9 TaxID=1365108 RepID=A0A0B1YLE5_9BURK +--AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCMALLQSNDKGAGNLLMGVLGGP +QAVTSFAHESGDPAFRLDRWEPELNQAAPGDLRDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMTGGARGATGIAAGVPPGWRVADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PSADAAARADVVASAAHIAT--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A1Y1BND1_9BURK +--AAQAELAALEKASNGRLGIAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIAQLCEAMLQSGDKGAGNLLMGVLGGP +QAVTSFAHGSGDTTFRLNRWEPELNQAAPGDERDTSTPVAMVDALQRLLLGDTLHEPQRT +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQANAAARADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000F512F49 +--SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDKGAGNLLMDVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSGAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix saharensis TaxID=571190 RepID=UPI00114DE8F7 +------HLIGLERRFDARLGVYAVNTGTGAAV-EHRADERFAFCSTFKGLAAAAVLHRNP +--LSHLDTVVRYTEGDLMASSFITRQHVATGMTIRQVCDAAVRHSDGTAGNLLLRDLGGP +AGLTAYARALGDTVTRSDRFEPNLTTAVPDDPRDTTSPRAIGEDYREIVLGDALDADKRA +FLRDLLERNATGALRVRAGVPQGWTVADKTGTGDHGTVNDIAVVWPPDAAPLVVSIMSSK +AGADAAYDQALLAEAAAYVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces nanshensis TaxID=518642 RepID=A0A1E7KV91_9ACTN +-----------------------------------------------------------D +GGEALLDARVRYSEDDLEEHSPVTGEHLDHGMTLGQLCDAAVRQSDNTAANLLLRELDGP +AGVTRFCRSLDDRVTRLDRWETELNSAEPGRTEDTTSPRAVARTYARLVLGDALEPPQRR +RLTDWLKRNTTGDDSLRAGLPEGWSIGEKTGSGAYGTNNDVGVAWAGDRTPVVLAVYTTK +HSAGAEPDYPLIAAATRLL---- +>[subseq from] class A beta-lactamase n=1 Tax=Acidocella facilis TaxID=525 RepID=UPI00047895C5 +---ATSFLAESERRTGGRIGIYARNLATGRTL-SWRADERFVMCSTFKMSLVACVLSRVD +KGEERLGRFVQYGAAQLSNYAPVARLHLADGMTVGAMCQAAIEVSDNTCADLLLLSVGGP +AALTRFWRAEGDEVTRLDHTEPRLNFSPPGDPRDTTTPAAMAGDLQRFLLGDALSPASRA +RLTGWMLNCQTGGALLRAGLPKGWKVADKTGNNGKDALGDIAVAWPAPDRPIVICAYTQG +GHPKPEILPPILAGVGRMV---- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio sp. 10N.286.48.B8 TaxID=2056189 RepID=UPI000D360D1B +-----ESIEQIESRVSGRIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDHE +NEGLDLESKVGVNSDELIAWSPVTKAFVGKEISLRGACAATMAMSDNTAANIVLASIGGP +NGLTEFLRSTGDRKTRLDHIEPDLNHARPGDERDTTTQKTMVKTLNKLLYGSALSEESKA +QLKTWMIDNKVSDGMIRSILPDGWKVADRSGAGAYGSRAITAIVWSENRAPLIISISLTE +TELTIPERDTVINEIGELIFDEy +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. 6K102 TaxID=2530382 RepID=A0A4R5FCB8_9ACTN +--QVKKYLRSLEVSFKGRIGAYALDTATGKTV-TYRAGERFPMLSTFKAPLCAAVLQKAR +TEPGLMNRLIKWTAADMKPNSPVTEKHVKDGLTVSQLCEAAVTMSDGTASNLLLKQVGGP +KGLTKYFRTLKDTTSQMDRWHPELNDWTPKDKRDTTTPAAMGRDLRVLTVGRALHAKDRR +QLLAWLLANKTGGERIRAGLPKSWTVADKTGTNSFGGGNDIAVVWPKKGAPVIMSIYTNR +TK-GLPTDNPTIAKTATILA--- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI0010C7B48E +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGHSIL--- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI000F0BB515 +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITHSDACFATMTTSDNTAANIVINAVGDP +KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ +TEASMAERNDAIVKIGRSIFEVy +>[subseq from] Beta-lactamase n=1 Tax=Phaeobacter gallaeciensis DSM 26640 TaxID=1423144 RepID=V9WGU6_9RHOB +--DLAETIRSWETALDARLGVLLIHPATGWEI-AHSADDRFPLNSTFKPLLCAAILSQVD +QGTEDLTARVEIRRKDLVSHSPVTERYIGTTRSLAQLCEATITRSDNTAANLLLERIGGP +EGFTEFMQISGDLITRLDRWETGLNSATPDDHRDTTTPRSVLSTLHVALSGTMLSGPSSA +QLADWMQRDQLADDLIRAHLPEGWTIGDKTGAGGHGSRGIIAFLRVPQGSEYLAAIYITE +TDANFARRNQAISDIGRAMVA-- +>[subseq from] Beta-lactamase n=1 Tax=Saccharothrix saharensis TaxID=571190 RepID=A0A543JQP1_9PSEU +------HLIGLERRFDARLGVYAVNTGTGAAV-EHRADERFAFCSTFKGLAAAAVLHRNP +--LSHLDTVVRYTEGDLMASSFITRQHVATGMTIRQVCDAAVRHSDGTAGNLLLRDLGGP +AGLTAYARALGDTVTRSDRFEPNLTTAVPDDPRDTTSPRAIGEDYREIVLGDALDADKRA +FLRDLLERNATGALRVRAGVPQGWTVADKTGTGDHGTVNDIAVVWPPDAAPLVVSIMSSK +AGADAAYDQALLAEAAAYVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium mageritense TaxID=53462 RepID=A0A5C7XW56_9MYCO +---LDGQISALEQRDNALIGIFATNLDNGRTV-TNRADDLFAMCSTFKGYAAGRILQQVG +RGQLSLDKRVFVDPGAVVANSPVTGPRAGSEMSLGELCQAALQQSDNTAANLLLRTMDGP +AGITAFARSIGDDRTRLDRWETELNSAIPGDPRDTSTPAALAAGYRRLLVEDALSPAQRG +QLEEWMRGNQT--SSLRAGLPAGWTTADKTGSGDYGSTNDVGVAYGPDGQRLVLAVMTRS +RADDADNLRPLIGELAA------ +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F56A4C8 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTSFRLDHWEPELSKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMAGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PDAAAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium marinum TaxID=1781 RepID=A0A3E2MR93_MYCMR +--DLESRFAELEQKYEARLGVYVPGTGATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP +--IAHLDTVITYNSADIRSTSPITEQHLETGMSIGGLCDATIRYSDGTAANLLLQDIGGI +AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALPPEKRD +KLIDWLGRSTTGAKRIRAGFPADWRVIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR +VGPEAPWCDPLVADAAKCVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium marinum TaxID=1781 RepID=UPI00045FDC78 +--DLESRFAELEQKYEARLGVYVPGTGATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP +--IAHLDTVITYNSADIRSTSPITEQHLETGMSIGGLCDATIRYSDGTAANLLLQDIGGI +AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALPPEKRD +KLIDWLGRSTTGAKRIRAGFPADWRVIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR +VGPEAPWCDPLVADAAKCVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. RTd22 TaxID=1841249 RepID=UPI000ACBB813 +--DVTRRLRALEEEYAARLGVFAFDPATGATV-AYRAEERFPMCSVFKALAAAAVLRDLD +RDGEFLAKRIHYTEEFVRKYAPVTGKNIAGGLTVEQLCAAAVSESDNAAGNLLLHDLGGP +TAITRFCRSLGDGTTRLDRWEPELNTAEPWRDTDTTSPGAIGKTFARLVLGRALTPEDRE +RLTGWLVANTTNIERFRKGLPADWILADKTGGGQYGVANDVGVVWPPERTPLVLSVLSTK +YDPQGPTDNPLVARAAALVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces gardneri TaxID=66892 RepID=UPI001144004A +---LTGRLRELEKEHSARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTLAVAAVLRDLD +HDGSFLAKRIRYTAAYVERFSPRTGENLAHGMTVAGLCDVTLRYSDNAAANLLLRELGGP +TAVTRFARSIGDGVTRLDRWEPELNSGEPWRDTDITTPRAIGRTYGRLVLGTALTPRDRD +RLTGWMLANTTSGERFRKGLPADWILADKTGGGRYGGNNDVGVAWPPTGGPVLLAVLTAK +PEEDAAADNPLVAGAAALVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf94 TaxID=1736250 RepID=UPI0006FBF0EC +----GAALARIAGDLGGRAGIAVLDTGGDPAL-LHDAEGAFPLCSTFKLLLAAAILARVE +AGRERLDRRLAYGEADLDTYAPVTTRALRAGMSVEALCAAALVWSDNTAANLLLAAIGGP +AALTAYGRDLGDPVTRLDRTEPDLNAAVPGDPRDTTRPAAMAATVGKILLGPSLTEASRA +RLEGWMTASRTGTKRLRAGLPADWGVGDKTGSGAYGTANVVALLRPPARAPLVAAIYLTG +SDTTSEARDAAHAAIGRVIAATy +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. DL90 TaxID=2487344 RepID=UPI000F5BA4D6 +---VDDQIAELERRDNALIGLYAANLDSGRIL-TNRPDEIFAMCSTFKGYAAARVLQMVG +RRQISLDNRVFVDPEAIVPNSPVTETHAGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGITAFARSVGDERTRLDRWEVDLNSAIPGDPRDTSTPAALAVGYRAVLAGDALSPPQRR +QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPNGQRLLLAVMTRS +QADDADNLRPLIGELTALV---- +>[subseq from] Serine hydrolase n=1 Tax=Aeromicrobium sp. Co35 TaxID=2590901 RepID=A0A554S799_9ACTN +-------LSAEAAEAGVDLSATVTDLSSGATF-QVGGQEPVKAASIIKLPLLAALMDEAD +QGRLSLDEVVTIEASNIVGGSGTLRDREPLDITIAELMELMVQVSDNTATNVLIDRAGGF +DGVNEYIEGLGFEHLWLGRKMI--HPASPPLQENWITSGEVNELVRMLYEHEVLSPESSE +HIISLMKGQLV-DTKFGAVIPRE-VLANKTGELVD-VSHDSGLILVPGRE-VALTVTTSF +DPIERPQVDVYVQRAASIVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Aeromicrobium sp. Co35 TaxID=2590901 RepID=A0A554S799_9ACTN +-----------ARANGIDIGVAIEDLSEDRQL-FLGAQDRFTTASTIKMSLAAAVMHQVE +RGQLSLDDVVTITEDERYGGSGTLKDNPFPQVSVGTLLELMVTVSDNTATNKLVDVVGGF +EAINTLTQDAGIAQRDLHFGRKMFGPVVPPDGDVWLTPRGMNRLMVLFYDPEFLSAESAQ +HIVELMLAQQV-KTKLGATVPAE-VLAHKTGENDV-VSHDVGMLLVPGQ-EMTLSVFSRG +AEDVQATANPYLQRIGAAVYAY- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. URHB0044 TaxID=1380386 RepID=UPI00048A86B7 +---IHDRIDALQQRHNAKIGVYGVDLTTGRSI-TYLDGERFAMCSTFKGYAAARVLRGSE +RGQLRLDDAVPIESADIVSNSPVTEPAVGGTLALADLCQAALQRSDNTAANLLLRAIGGP +PAVTDFARSIGDDETRLDRWETELNSAVPGDLRDTSTPRALGGGYQNLLTGDALAPASRD +LLETWMRANVT--SSMRAGLPPGWTSADKTGSGDYGSTNDVGIVYGPDGRRVLLSIMTRS +RTDDAENLRPLIGE--------- +>[subseq from] Beta-lactamase n=1 Tax=Microbispora sp. SCL1-1 TaxID=2592812 RepID=A0A544XQ11_9ACTN +--DVTAALRALEASFKGRIGAYAIDTATGKTI-GYRAGERFPLLSTFKAVAAGAVLARTT +-DRELTRKVVHWTADEVKSNSPETGKHVKDGMTLAELCRAAIIYSDNTAGNMLLKRIGGP +RGLTRYFRTLKDPVSRLDRWETDLNIWSPKERRDTTTPASVARDLRVLTTGGVLGAKDRS +RLIGWLRDNTTGDARIRAGLPKTWIVGDKTGTGGYGTANDIAVIWPANAAPIIMAIYTNR +RAADGATADSVVARTATLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Amel2xB2 TaxID=1305829 RepID=A0A327UEK0_9ACTN +--EVARGLRKLERQHSARVGVFARNMRTGTTL-VHRADERFPLCSTWKPLAVAAVLAGRG +GGEALLDARVRYSEDDLEEHSPVTGEHLDHGMTLGQLCDAAVRQSDNTAANLLLRQLDGP +AGVTRFCRSLDDRVTRLDRWETELNSAEPGRTEDTTSPRAVARTYARLVLGDALEPPQRR +RLTDWLKRNTTGDDSLRAGLPEGWSIGEKTGSGAYGTNNDVGVAWAGDRTPVILAVYTTK +HSAGAEPDYPLIAAATRLL---- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium rutilum TaxID=370526 RepID=A0A1H6L8B8_9MYCO +---LDSRLRDLEREHNALIGVFATNLDSGRTV-AHRAAESFAMCSTFKAYAAARVLQLVE +RGGLTLDQRVFIDAADILANSPRTQTQVGGEMTLDELCQAAVQVSDNAAANLLLRTLGGP +QAITAFARSIGDERSRLDRWELELNAAVPGDPRDTTSPEAIGGGFRAILTGTVLAEPQRR +LLEQWMRANET--SSMRAGLPDGWTTADKTGSGDYATTNDVGIAYGPSGERLLLALMTRT +AGADAPGLRPVIGEVAALLV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces gardneri TaxID=66892 RepID=A0A4Y3REC6_9ACTN +---LTGRLRELEKEHSARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTLAVAAVLRDLD +HDGSFLAKRIRYTAAYVERFSPRTGENLAHGMTVAGLCDVTLRYSDNAAANLLLRELGGP +TAVTRFARSIGDGVTRLDRWEPELNSGEPWRDTDITTPRAIGRTYGRLVLGTALTPRDRD +RLTGWMLANTTSGERFRKGLPADWILADKTGGGRYGGNNDVGVAWPPTGGPVLLAVLTAK +PEEDAAADNPLVAGAAALVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodovulum sp. MB263 TaxID=308754 RepID=A0A1V0HUS4_9RHOB +--TLADTVERVESRLGARVGVSLVDTGSGLSW-THRENERFLMNSTMKVPLCGAVLARRD +AGELSLQTELPVRKSDLLDYAPVAKKRAGGEMTIAELCLAAIDMSDNTAANLLIEHLGGP +QAVTRFFRSAGDRISRLDRTEPALNTFNAADLRDTTTPAAMTETLRGLLLGDVLSRSSRT +QLAAWMSQGGVTGNLLRAEAPEGWVILDKSGSGTH-TRNLVALVTPVDASPWIVTIFVSD +VDADAQTRNRALQDIGRAVM--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces himastatinicus ATCC 53653 TaxID=457427 RepID=D9W718_9ACTN +--DVTRQLRALEEEYAARLGVFAFDPATGATV-AYRAEERFPMCSVFKALAAAAVLRDLD +RDGEFLAKRVHYTEEFVRKYAPVTGKNIAGGLTVEQLCAAAVSESDNAAGNLLLHDLGGP +TAITRFCRSLGDGTTRLDRWEPELNTAEPWRDTDTTSPGAIGKTFARLVLGRALTPEDRK +RLTGWLVANTTNIERFRKGLPADWILADKTGGGQYGVANDVGVVWPPERTPLVLSVLSTK +YDPQGPTDNPLVARAAALVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio sp. V19_P1S1T109 TaxID=1938672 RepID=UPI000B8EA25D +--QLTQSVKDIESDWQGRIGVYAYDIYGSFTF-GYREQERFPLCSSFKSLLAAAILQKSQ +NQLLNLDTSIDFSERDLEFWSPITEENHAEGMTIGQLAQAALQYSDNGATNILLERIGGP +KGMNTFMKSIGDEDFRLDRWELELNTAIPGDERDTSTPKSMATSIGKLSFGNVLSASHQE +LFHDWLIGNTTGDNRIRAAVPKQWQVGDKTGTCGYGAASDVAVIWREKASPLVIAIYTHK +SEPSAKHSDKIIAEVAKETLQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. 155 TaxID=1157943 RepID=UPI000368BC85 +---LDDQIAGLEQRNNVLIGIFAANVDSNRTV-AHRADETFAMCSTFKGYAVGRVLQQVD +RAQLALDTRIFIDPSAIVANSPVTERRAGADMTIGELCQAALQHSDNTAGNLLLKMIDGP +PGITAFARSIGDNRTRLDRWETALNTAIPGDLRDTSTPAALGGGYRALLAGDVLSPPQRQ +QLEDWMRGNET--SSMRAGLPADWTSADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS +RADDPKAANPLIGEL-------- +>[subseq from] class A beta-lactamase n=1 Tax=Microbispora sp. CSR-4 TaxID=2592813 RepID=UPI0011C83F0B +--DVAAALRALEASFKGRIGAYAIDTATGKTI-GYRAGERFPLLSTFKAVAAGAVLARTT +-DRELTRKVVHWTADEVKSNSPETGKHVKDGMTLAELCRAAIIYSDNTAGNMLLKRIGGP +RGLTRYFRTLKDPVSRLDRWETDLNIWSPKERRDTTTPASAARDLRGLTTGGVLGAKDRS +RLIGWLRDNTTGDARIRAGLPKTWIVGDKTGTGGYGTANDIAVIWPANAAPIIMAIYTNR +RAADGATADSVVARTATLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Kocuria sp. 257 TaxID=2021970 RepID=UPI0010104031 +--DMASKIRELEHELDGEIGVYAFDTSTGACF-GYRDQQRFLFCSVSKVLVAATVLNRAS +QDPTLLERRVSITREDILAYAPVTSQHLEDGMTVEELCAAALTVSDNTASNLLMEQCGGP +EAVTAFVRSTGDVTTRLDRIEPDLNEA--SGVLDTTTPAAFSETLNRLTLGDALTASGRD +KLVGWMKESTTGAEQIRAGLPEGTLTGDKTGSGTHGESNDVAVIWPQQGAPVIMSVFTKS +HRTDTVGQKAAIAGTAEAVFE-- +>[subseq from] Beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A3D0L606_ALCFA +-----QAAQQAESSLQARVGLAVLDTADGQRW-HYRADERFPMASTSKALICAALLARGQ +---GAMKTAWLVQQEAIQSYSPTTEKMVGEYVPAAQLCAITMRNSDNTAANGVLEMLGGP +AAVTSFVRTVGDSVTRLDRNEPTLNEARPGDPRDTTTPQAMVQTLQNLVLGDALEPHARE +RLIAWLRNNKVGGPLLRAGVPEDWTMADRTGAGGFGTRGVVAVIWPPKRAPLIAAVYVTE +TEAPMEDSNTAIAMIGKAIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Comamonas sp. lk TaxID=2201272 RepID=UPI000EAFCD0F +---LAEELAQIEIQAQGRLGLYVIDTSSGATA-GYRSDERFPMCSTFKTLLAARVLYLAQ +KGQIELWRKRYFSPSELVPWSPVTEKRAGANMTPLELCEAAVVFSDNTAANVLLDATGGP +AALTAWLAEIGDKTTRLDRREPQLNTAIAGDERDTTTPAAMAQTLQTLQRGDVIEGFGRA +FLRQWLIESRTGDKRLRAGMPTDWKFGGKTGSGENGTACDNLVVWPPQSSPILVTAYLTG +SKLDGPGRDAVLAKAGEAVKR-- +>[subseq from] Beta-lactamase n=2 Tax=Lapillicoccus jejuensis TaxID=402171 RepID=A0A542DWC9_9MICO +--STDRAFAALERTHDATLGVTAVDTGTGRTV-SWRPGTRFPFASTNKTFIAAAVLDRSS +--EADLDVVVRYTRADLLAYAPITSRFVDTGMTVRELLDAALRFSDNTAANLLVERVGGP +AAVQAWLRAHGDRVTRVDRVEPGLNEALPGDPRDTTTPAQFAQDVRDVVLGSDLALADRT +LLRDLMLGCTTGDGTVRAGVDPAWPVADKTGTGEYGVRDDVAVVYPAGRAPVVVTVFTRQ +DAPDATPADALVAAATRVAVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SB3404 TaxID=2711219 RepID=UPI0013EB7C4B +--ALSRRFRALESEYGARLGVYARDTDTGATV-AYRAAERFPMCSVFKAPAVGAVLRDLD +RDGEFLAKRVHYTQWLVRKYAPVTGKNLANGLTVGELCAAAVGESDNAAANLLLRELGGP +TAVTRFCRSLGDDTTRLDRWEPELNSSEPWRISDTTTPGAIGATFGRLLVGRALPRRDRE +RLTGWLVANTTNTDRFRAGLPEGWVSADKTGGGDYGVANDVGVVFPPGRGPLVLAVLSTT +YAAEGPQHDAIVARAVKLVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D000075 +--RAQSELAALDKASGGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDKGAGNLLMDVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Aureimonas sp. Leaf454 TaxID=1736381 RepID=A0A0Q6BM52_9RHIZ +--------ERIEAQVGGRLGVSIRDLQTGASF-SHRGSERFPMASTFKAFACAHLLALAD +AGTIDPGRREPIRAGDLQTYSPVTRNHVGDGLSLSALCEATTRTSDNTAANLILTATGGP +AALTAFLRSIGDDTTRLDRFEPDLNDVGPGDDRDTTSPDAAIASLQKLVLGDVLSANSRR +QLESWLAANAVGGPLLRASLPEGWRIADRTGAGEYGTRGIIAVIWPKAKGPILAAVYLTG +TKLSIDQRNGVIAELGAAMVE-- +>[subseq from] Beta-lactamase n=1 Tax=Actinosynnema pretiosum TaxID=42197 RepID=A0A290Z8G0_9PSEU +------AFAALEQRFDARLGVYALDTGSGRVV-AHRADERFAYASTFKALAFGALLAERS +--VADLDERVTFTREELVTYSPITEGRVDSGMTLREVADAAVRYSDNTAGNLLLRELGGP +AAFERALRAIGDTTTSPARVETELNEAVPGDLRDTSTPQALAADLRRYAVADVLPDDRRE +LLVSTMRANTTGDEVIRAGVPQGWVVADKTGSAGYGGRNDIAVLWPPDRAPIVLAVLSGK +ATADAVHDNALLAEATRAVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. KC13 TaxID=2711220 RepID=UPI0013EC26E7 +------SIAALEQTHQRRLGVWAKNMRTGRVI-EHRADERFPMLSTFKTLLTAAILRDLP +--ARTLQQRLTWDAADVVVNSPVTSVTTRNGLTVAQLAEATMTRSDNTAANELLHLIGGP +AGVTRFARSLGDTVSRLDRWEPDLNSAIPGDPRDTTSPRAIAQTYTKLVLGDALDRGDRD +QLITWMLANQSTVTRFGAGVPAGWRLADKTGGGDYASRNDVGVTWTPDGAPIVIAALTRS +DDPTAAPLDKPLEDIAATVCA-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=UPI000F56F92A +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS +LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTAFARASGDMSFRLDRWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRT +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonadaceae bacterium KCTC 52780 TaxID=2172047 RepID=UPI000E0D6505 +--------------ASARFGFAAVDTASGRSV-VHDADSRYAMCSTFKWTLAAAILAEAE +AGRLQLDALIPFGEADLLGHAPVVRENIGAGLPVERLCAAIVEVSDNSAANLLLRRIGGP +QALTAFIRANGDDVTRLDRYEGALNSNLPNDPRDTTTPAAMVRLMERLLVGDALTPASRT +RLLGWMERSTTGLDRLRAGLPSDWRVGDKTGTGANGAHNDVAVAWPPARPPLLVASFISA +AQASGDACNAAHAAAGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Segeticoccus rhizosphaerae TaxID=1104777 RepID=UPI0012650F1A +---------------------------------SFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Roseomonas oryzicola TaxID=535904 RepID=UPI00143A9F80 +---LPGEFARIERSQGGRLGVAVLDTGGRRAA-EHRGGDRFPMASTFKMLLGGAVLARID +AGQDSLERRIRFGRGDLVTYSPATEGQAGGEMTVAALLEAMMTLSDNTAANLLLSAIGGP +EGLTAFLRRHGDAVTRLDRMEPALNEGTPGDPRDTTSPAAMLATMRALTLGEALSAPSRA +RLVWLMEGNRVSGSLFRARLPQGWRIGDRSGAGGFNTRGIAAVIWPSGGAPLLVTAYLTE +PQRTLAARDAVLAEVGGAIFAAy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075B1E54 +--SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDKGAGNLLMDVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D0060E6 +--SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDKGAGNLLMDVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A0J5WTR8_BURCE +--AAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTAFRLDRWEPELNLAAPGDERDTSTPVAMVDMLQRLLLGNTLQEPQRT +QLTEWMTGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPLVMAVSFTQ +PQADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Kribbella amoyensis TaxID=996641 RepID=A0A561BU07_9ACTN +----HDQLLALERKYGARLGVYAVATGTGRTL-AHRADERFAFCSTFKGLAAAGVLHHNP +--LTHLDTVVTYTTDDLMKSSVITRQHVRTGMTLRQLCDAAVRYSDGTAGNLLLRELGGP +AALTAYLRTLGDQVTRMDRYEPHIVTAIPGDPRDTTTPRAIGTTYQNLVVGKALAPEKQA +HLRDLLERNATGRRRIRAGLPKSWTVADKTGTGDYGTTNDIALTWPPQAPPLLIAILSSK +PQEQAPSTSALLAEAATYT---- +>[subseq from] Beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=A0A379CPC3_PLESH +--ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD +AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP +AALTAYLQSIGDNVTRLDRNEPTLNEAAKHDPRDTTTPNAINHTLNTLVLGETLSSTSRQ +QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQDPMFVSIYLTQ +TEATFDERNAAIVTIGKSIFDTf +>[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia diazotrophica TaxID=667676 RepID=A0A1H6U2Y8_9BURK +---AHERFEQLEARSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLAVAAILKRSI +AERALLDTHIRYGEMDLVANSPVTKRHVSEGMSMGEICAAALQYSDNTAANLLLTALGGS +EVLNEFARSIGDTWFDLVRREPELNDAVPGDMRDTTTPRAMMRDMQKILLDDVLEPPQRE +KLKAWLLGNATGERRIRAAVRSGWPVADKTGSGDYGTANDVAVVYSPAAA-FVVAVYFTG +VTKETPPQDEVVDEAARIVFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium lablabi TaxID=722472 RepID=UPI0009A7B8F9 +------ALAAYERDTGGRIGVYAENLSTGAKI-AWRAEQRFVMCSTFKASLAALMLARVD +RGEDRLEDMVAYGRKDILDYAPVAKQNLAHGMSVSDMCKAVVELSDNTCANLLLARAGGP +EALTAFWRSTGDTLSRLDHNEPELNRSPPGNPHDTTTPSAMAGNLRRFLLGAVLTPPSRE +HLTEWMVGCKTGNNRLRGGLPRDWKVGDKTGNNGKDASGDIAIAWPKSGGPVLVCAYTQG +GSPTPQQFEAVFKEVGAMV---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. EsD8 TaxID=1301088 RepID=UPI0005C92EB7 +--RLDAVLADLEERRRVRLGVLAHDPGRGLTY-ARRADDRFAMCSTFKVYAAAAILRLES +QGSLRLDDTVPVDPADIVENSPVTSEAQGRTLTLAQLCDAALTRSDNTAGNLLLRRLGGP +TAVTAFARSLGDTATTLDRWEPELNSAEPGDVRDTSTASGLARGYRELLLGSGLPAAGQQ +TLMDWMRASVTSGQRIRAGLPAGWTAADKSGAGRYGTVNDAGVLWSPDGSPLVLVLLSDS +VTPDAAHDNAAIAEATAVIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas sp. NML140781 TaxID=2480812 RepID=A0A4Q8LNE8_9GAMM +-----RDFAALEQVSGGRLGVTLLEVGTGRRM-GRRQDERFPMCSTFKALLAAHVLSLAD +AGALSLDERLPIRQAQLLSWAPESERHVGKDLTVRDLCRAAVTNSDNTAANLLLARAGGP +PALTAFLRKQGDAVTRSDRYEPAMNGFALDDPRDTTSPAAVAASLARFAVGDGLSKASRA +QYADWLIDNQTGDDCLRAGLGKRWRVGDKTGNNGRDTRNDLAVLWPLGGTPWVLVALLQG +ARVDADQRDAVLARVGALA---- +>[subseq from] class A beta-lactamase n=1 Tax=Jiangella muralis TaxID=702383 RepID=UPI00069E1511 +--AVAAALTALEGDYAARLGVYAIDTGTGRTI-EHRPDERFAFASTHKMLSAAAVLLATE +--PADLEQLIEVDAAEVVGWSPVTEPAVGAGLTLLEVIQAAVTVSDNTAANLLFEQVGGP +DGLEAAVRGFGDETTSFDRIEPDLSDWVPGETRDTTTPRAMAANVRGLLLGDLLAEEDRT +LLHDTMRANTTGDELIRAGVPDGWVVADKTGSATHGGRNDVAVIEPPGAAPIVLAVYSNR +LDPEAESDPALIAAATEVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759C44F +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA +LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLSEAMLQFGDKSAANLLMSVLGGP +QTVTEFARASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPGRA +QLTKWLLGSANGVAGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADAAPRADVIAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000753B60F +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA +LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLSEAMLQFGDKSAANLLMSVLGGP +QTVTEFARASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPGRA +QLTKWLLGSANGVAGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADAAPRADVIAEAARIAA--- +>[subseq from] Beta-lactamase n=2 Tax=Mycobacterium marinum TaxID=1781 RepID=A0A2Z5YG60_MYCMR +--DLESRFAELEQKYEARLGVYVPGTGATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP +--IAHLDTVITYNSADIRSTSPITEQHLETGMSIGGLCDATIRYSDGTAANLLFQDIGGI +AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALPPEKRD +KLIDWLGRSTTGAKRIRAGFPADWRVIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR +VGPEAPWCDPLVADAAKCVAD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=A0A3N8Q4R1_9BURK +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS +LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFVRASGDTSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRA +RLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Comamonas thiooxydans TaxID=363952 RepID=UPI0007C562CC +---LSDELAALEVQARGRFGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARVLYLAQ +RDEIRLWRKLYYAPSEVVAWSPISEKWAGANMTVQELCEAMVLVSDNTAANVLLEASGGP +AALTQWLRELGDGTSRLDRNEPSLNTALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA +LLQQWLVDSRTGDKRVRAGMPGDWTVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG +SPLDGAGREAVLARAGEAIK--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoalteromonas denitrificans TaxID=43656 RepID=UPI000B89CB3A +---IIKKIEEQERQLGARIGVSIYDVTDNKLW-HYNGNTRFPLMSTFKVLACAKLLFDVE +KGLQSFDTSTVITKNSLIEWSPVTKNMIGEKISLKQACSATMSMSDNTAANIVLNGIKGP +KVLTRFMRSIGDDVTRLDRIEPDLNEALDGDKRDTTTPNAMVKSLHTLLFGDALSQASKT +QLKQWMIDNKVTGKLLRKVLPQNWSIADRSGSGGYGSRGITAVVWSDKRTPLIISIYLTQ +TEASFSQRNKAIANIGKEIFTVy +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. AG1037 TaxID=2183990 RepID=UPI000E0B13A9 +---TRQAFADLERRDGARVGVVAVDTGTGRSL-GYRADERFAFASTNKVQIAAAALAASS +--PADLDEVVHYDRGDLLSHVPVTTPAVDTGLTVRQLVDAAIRQSDNTAANLLVERVGGV +AGVTRWLRGLGDTTTDVSRTEPDLNTALPGDRRDTTTPAQSAADLRAVLLGDALDADDRS +LLRNAMLGTTTGATTIRAGVDPSWTVADKTGTASYGVRNDVGVVTPPGRDPIVLVVMTAH +GTVDAEPSDALVADATRIAIAH- +>[subseq from] Beta-lactamase n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=Q2QCK2_SALTM +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKAELVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVKNQVTGNLLRSVMPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGHSIFDVy +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus TaxID=1827 RepID=UPI000569115E +--RLDAVLADLEERRRVRLGVLAHDPGRGLTY-ARRADDRFAMCSTFKVYAAAAILRLES +QGSLRLDDTVPVDPADIVENSPVTSEAQGRTLTLAQLCDAALTRSDNTAGNLLLRRLGGP +TAVTAFARSLGDTATTLDRWEPELNSAEPGDVRDTSTASGLARGYRELLLGSGLPAAGQQ +TLTDWMRASVTSGQRIRAGLPAGWTAADKSGAGRYGTVNDAGVLWSPDGSPLVLVLLSDS +VTPDAAHDNAAIAEATAVIVE-- +>[subseq from] Beta-lactamase n=2 Tax=Tardiphaga sp. OK246 TaxID=1855307 RepID=A0A239NXU4_9BRAD +-----AALLAYERDTGGRIGVYAENLKTGAKI-AWRANERFVMCSTFKASLAACVLARID +RGEDKPDQMISYAAADLLDYAPVARDNLAKGLSVADMCKAIVELSDNTCANMLLARVGGP +AALTAFWTKTGDSVSRLDHNEPLLNRSRPGNPQDTTTPTAMAGNVKRFVTGNVLTAASRD +QLTDWMVNCKTGDKRLRAGLPKSWKIGDKTGNNGKDAAGDIAVTWPKPDQPVVIAAYTQG +GTPTAPQLETVFTAIGEMV---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0007556269 +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDKGAGNLLMDVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Pseudoalteromonas TaxID=194690 RepID=UPI0005AA1CF4 +--TISKKIEEIESQLDARIGVSIYDVTDNKLW-DYNGDTRFPLMSTFKTLACAKLLVDVE +KGLQSFNTSSVITKSSLVKWSPVTKKHVGELFTLKQACSAAMIMSDNTATNIVLASIKGP +KELTRFMRSIGDDVTRLDRVEPYLNEALDGDKRDTTTPTAMVKSLHTLLFGDILSQDSKV +QLKQWMIDNKVTGSLFRSVLPEGWSIADRSGAGGYGSRGITAVVWSDKRSPLIISIYLTQ +TDASFALRNKAIANIGKEIF--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderiales bacterium PBB6 TaxID=2015568 RepID=A0A257CF86_9BURK +---LATLCAGLESQHGGRIGVCLMETRTGRLW-QYRADERFAMCSTFKLLLAAAVLTQVD +AGRLSLQQTVAVRKTDLVPYAPVMEGLLGTRVPLGMLCEATVGVSDNAAANVLLPWVGGP +AGLTRLLRAWGDAVTRLDRNEPELNSNLPGDARDTTSPAAFARTVASVVHGSTLSSQSRQ +QLQLWLRGASTGMNRLRAPWPADWQAGDKTGTGPRGAVNDVAVAWPPGQPPLVLAVFMGG +STATSDNLNAAHAAVARWAM--- +>[subseq from] class A beta-lactamase n=1 Tax=Lechevalieria xinjiangensis TaxID=402600 RepID=UPI000B7CAFEE +-----DALAELERKFGARLGVYAT--GAGGTV-EHRADERFAFCSTFKGLATAAVLHRNP +--MSHLDTVVTYTEAELMKSSAITRQHVRTGMKLRDLCDAAVRYSDGTAGNLLLRDVGGP +AELTRYLRELGDTETRMDRVEPDITSATPGDPRDTATPRSLGTDYRRLVLGDALPPEKRD +FLTDLLERSVTGAKRVRAGVPQGSRVASKTGTGSYGTVNDIAIVWPPGGEPLLIAVMSSK +DAADAGYDEALVAEAAAYVVK-- +>[subseq from] Beta-lactamase n=1 Tax=Alcaligenaceae bacterium 429 TaxID=2562948 RepID=A0A4S1E6S5_9BURK +-----QKAAAIEEQLQARVGVAVIDTASGQSW-LYKADERFPMASTAKTLVCAALLQQGE +---PLLHSPVLLQPDDIQTYAPVTKELVGQTMSAFQLCEITLRSSDNTAVNLVLNVVGGP +SAVTSFLRRIGDQVTRLDRLEPEVNEAKPGDERDTTTPAAMAATMRALLLDSALNPTMRA +QLVEWLKANDVAGPLLRAGVPSDWVVADRSGSAEYGTRGVAAVMWPTQHAPIVAAVYITE +TDAPIEARNAAIASIGQAIAE-- +>[subseq from] Beta-lactamase n=2 Tax=Roseivivax TaxID=93682 RepID=X7F2J9_9RHOB +-----DLVRETEQALGARVGLVVRDSGSNWSW-DHRADERFLMNSTLKAPLCGAVLAQVD +AGAIDLDEALPVRPEDMVDYAPVTENEVGGTMSVDDLCLAALDMSDNAATNIVIDRLGGP +QEVTTFLRGIGDEVTRLDRKEPDVNTFDPADPRDTTTPEAMTRTLEALLAGDALSAGSRA +RLTAWMTPGGVTGAHFRAHVPRDWRIADKSGAGDF-TRNIVAMITPPGAEPYFVAIYLSG +ADADFETRNAAVIALSAAVVD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KJ38_9BACT +-----SLFQELEEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS +--IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFTLLDGP +NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLAFNLKEYVTGDILSDDKKE +IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRNDIAIVTPPNKKPIFVAVLSKK +AEQDAEYDNKLIADATKIIFD-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio barjaei TaxID=1676683 RepID=A0A1J4R8E1_9VIBR +--TLDESIASIEQRISGRIGVSVFDSSNQQQW-HYRGNERFPMMSTFKTLACAKMLHDAD +SGELDKNTLAPITSDKLIPWSPVTEKMVGSSITINKACEATMETSDNTAANIVLHSIGGP +QALTEFLRLNQDDVTRLDRIEPELNQAVSGDIRDTTTPNAMNTTLHRLLFKGALNQDSKN +QLMAWMQGNTVSDSLLRSILPQGWSIADRSGAGANGSRGFTGVLWADNRNPLIISIYLTQ +TDLSMSERNQIINEIGGLIFQTy +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A5P2JZ93_9BURK +--RAQAELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNAVGPGDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. D16Q20 TaxID=1855660 RepID=UPI000993056F +-----TELASLEKDFGGRIGVYALDTGSGATL-GHRPNERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYTQSDVLEWAPIASQHVAEGMTVSQLCDATIRYSDNTGANLLIAQLGGP +KQTEKYVRSLGDNVSRMDRTEEELN--IPDGDLDTSTPLQLVTNLRRLVLDEGLDPQGRD +LLTDWLKRNTTGDQSVRAGVPAGWAVADKTGGGFKSETNDIAVIWPPGRAPIVVAVLTVP +DDPKSTKSKPTIAAATRIALKAf +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. EsD8 TaxID=1301088 RepID=N1M7B0_9NOCA +--RLDAVLADLEERRRVRLGVLAHDPGRGLTY-ARRADDRFAMCSTFKVYAAAAILRLES +QGSLRLDDTVPVDPADIVENSPVTSEAQGRTLTLAQLCDAALTRSDNTAGNLLLRRLGGP +TAVTAFARSLGDTATTLDRWEPELNSAEPGDVRDTSTASGLARGYRELLLGSGLPAAGQQ +TLMDWMRASVTSGQRIRAGLPAGWTAADKSGAGRYGTVNDAGVLWSPDGSPLVLVLLSDS +VTPDAAHDNAAIAEATAVIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodovulum sulfidophilum TaxID=35806 RepID=UPI0009532D08 +--TLADTVERVESRLGARIGVSLVDTGSGLSW-THRENERFLMNSTMKVPLCGAVLARRD +AGDLSLQTELPVRKSDLLAYAPVTEKRAGGEMTIAELCLAAIDMSDNTAANLLIARLGGP +QAVTRFFRSAGDTISRLDRNEPELNTFNAADLRDTTTPVAMTETLRGLLLGDVLSRSSRG +QLAEWMSHGGVTGNLLRAEAPEGWVILDKSGSGTH-TRNLVALVTPVDGSPWIVTIFVSD +VDADSQTRNRALQDVGRAAM--- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia steynii TaxID=1245441 RepID=A0A4R0X6V1_9BURK +---ARERFEQLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM +AERSLLDERVRYGEADLVANSPVTRRHVGEGMTIGELSVAALQHSDNTAAKLLLTAVGGP +EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGSQQRE +QLKAWMLGNVTGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVVAVYFTG +VMKQTLPRDEVVVEAARIVFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Afipia sp. GAS231 TaxID=1882747 RepID=UPI000B87702E +-------LAAYERDTGGRIGVYAENLSTGAKI-AWRAEERFVMCSTFKASLAAFVLARVD +NAEDRLEDMVAYGAKDLLDYAPVAKQNLAQGMSVADMCKAIVELSDNTCANLLLARVGGP +AALTEFWSRTGDAVSRLDHNEPELNRSPPGDPRDTTTPSAMAGNLRRFLLGTVLTPSSRE +HLTQWMVDCKTGNNRLRGGLPADWKIGDKTGNNGKDASGDIAIAWPKSGGPVLVTAYTQG +GSPTPPQLETVFKEIGAMVAQ-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. ICBB 8177 TaxID=563922 RepID=A0A2U3C791_9ACTN +-nAVEARLLDLEARHSARLGVFARNTATGRTV-AYRARELFPICSAHKVISVAALLKDLD +VHGDFLAERITYTVKDTTDYAPVTGTHLAHGMTVAQLCAAAIEYSDNAASNLIVRQLGSP +QAVTRFCRSIGDRTTRLDRWEPALNSAEPWRVTDTTSPVAVARTYARLVLGGVLSRAHRN +LLTGWMLADTTSGQRFRAGLPRDWRLADKTGTGDYGTANDVGIAWTPDGTPVVLSVLSTK +HDPKAQADEPLIAEVAAVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces rimosus subsp. pseudoverticillatus TaxID=1464079 RepID=A0A0M8RGF8_STRRM +----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD +HDGSQLARVIRYTEADVTKHAPVTKDHIDTGMTIQDLCDATIRYSDNCAANLLLRELGGP +TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA +LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAITWTPDGAPVLLTALTHK +PSPTAPGDTPLIIKLATV----- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Aeromicrobium TaxID=2633570 RepID=A0A5F2ETI9_9ACTN +---TRGDFAAIETSYDTRLGVFALDTGTGRRV-SWRSSERFPFASTIKAPLAAVVLDRTS +--RRDLSRTITYDASDLVPHSPVTEKHVADGLPLRDVIDAALRFSDNTAANLLFDQIGGP +AGLDRELDRIGDRVTNPVRTEPDLNTATPGDVRDTTTPKALATTVGTYVVGRALPRHDRD +LLRTTMTNNTTGDALIRAGVPDGWVVADRTGGASHGVRTAVAVAFPPGRSPVLIAVMSRR +DQADDEYDDGVVADATRVAVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. QIA-37 TaxID=1561223 RepID=UPI0007A0E94B +--------TALEDWYGARIGVYAVDLDSLRTV-EHRADERFSMCSTFKTYAAARILQLSD +AGAADLDTKITIARDDVVVDSPITRDAIGSSMPLGDICAAALTHSDNTAGNIMLRTIGGP +AAITTFARSIGDTHSRLDRWEPDLNTAIPADPRDTTTPKALCTGYRRILTADVLATPARD +RLLTWMKSNVTSSKRFRAGLPPGWTSADKTGAGDYGSTNDAGLLIGPNGQRVVAVVMTRS +RDHDAPPFNEAIAGAIRV----- +>[subseq from] Beta-lactamase n=2 Tax=Rhodococcus TaxID=1827 RepID=A0A059MVZ9_9NOCA +--RLDAVLADLEERRRVRLGVLAHDPGRGLTY-ARRADDRFAMCSTFKVYAAAAILRLES +QGSLRLDDTVPVDPADIVENSPVTSEAQGRTLTLAQLCDAALTRSDNTAGNLLLRRLGGP +TAVTAFARSLGDTATTLDRWEPELNSAEPGDVRDTSTASGLARGYRELLLGSGLPAAGQQ +TLTDWMRASVTSGQRIRAGLPAGWTAADKSGAGRYGTVNDAGVLWSPDGSPLVLVLLSDS +VTPDAAHDNAAIAEATAVIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio mediterranei TaxID=689 RepID=A0A241TD39_9VIBR +--TLDESIASIEQRISGRIGVSVLDSSNQQQW-HYRGNERFPMMSTFKTLACAKMLHDAD +SGELDKNALASITSDKLIPWSPVTEKMVGSSITVSKACEATMETSDNTAANIILHSIGGP +QGLTEFLRLNQDDVTRLDRIEPELNQALSGDKRDTTTPNAMNTTLHRLLFEGALNRGSKN +QLIAWMQGNTVSDSLLRSILPQGWSIADRSGAGANGSRGFTGAIWADNRKPMIISIYLTQ +TDLSMSERNQIINEIGGLIFQTy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007C7E2D6 +--SAQAQLAGLEKALDGRLGVFAWDSTKNVVL-AHRATERFPVNSTFKALLAGQALALDA +HPPGLMNKYLAVSAGDIIKHAPVTEKFVGRNMTVAQLCQATVETSDNPAANILMRELGGP +ESLTSFMRSIGDNTFRLDRYEPELNTAIPGDLRDTSTPEAMVRSLHTLTLGGGLRPPQRE +QLRNWLLGTVTGSRRIQAGVPPGWRVAGKTGSGAYGAAHDLGLIWPPDRPPIVLAIYSHL +NEPNAAWREEIIAAAARIV---- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium stomatepiae TaxID=470076 RepID=UPI0013D83C5D +---FYDRLAELERQYNAYIGLFATHLGSGRTL-AHRDDDPFAMCSTFKAYAAARVLQKTQ +RGELDLQQRVFIDPAALLPNSPVTAPQAGNTMPLAQLCAAALQHSDNAAANLLLAEVGGP +PAITDFARSIGDERTRLDRWEVELNAAIPGDPRDTSTPRALGAGIQNLLTGTVLGEAQRS +QLERWMRDNVT--SSMRAGLPPGWTTADKTGNGDYGSTNDIGMVYGPSGQRVSLSVMTRS +QSRDADALRPLIAEVTKSVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Mannheimia haemolytica TaxID=75985 RepID=UPI000BAAA59F +--TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP +--EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV +EQYQRILRQLGDNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT +ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ +FTK-------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea zeae TaxID=1642303 RepID=A0A5S4GL93_9ACTN +--QVTKELRALEASFKGRIGAYAIDTGTGRTI-AYRSGESFPLLSTFKAVACAAALNKAR +TEPGLMAKVVHWTSAEVKENSPATEKHVRDGMTVSALCEAAITLSDNTAGNMVLKQIGGP +AGLTRYFRTLKDPVSRLDRWETELNDWTPKEKRDTTTPAAMGRDLRALTTGSALTAKDRK +TLNAWLKANQTGDARIRAGLPPSWTVGDKTGANPAGLTNDVAVVWPGKSAPIILSIYTNR +SASDADASNQAIAKTATILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Falsirhodobacter sp. alg1 TaxID=1472418 RepID=UPI00078690CF +---LLPTVAQIEARLDGRIGLSLIETGSGRSW-TYRKDERFPMNSTVKVPICATVLARRD +AGKLSLSDILRVNQEDILSYAPVTEKTVGAGMSLADLCLAAIDMSDNTAANMLVDHIGGP +QAVTDFLRGTGDELSRLDRREPELNNFLSGDPRDTTTPAAMTETLRRLLLGNALSSESGK +QLAEWMSIGGVTGNLLRADAPEGWIILDKSGGGSH-TRNIVAVVIPEGGSPWIVTIFISD +VDADSSTRNAALQQIGSAVM--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0003710E33 +--STTARLRELERVHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD +RDGEVLDKVIHYTGADCVSDSPITNTNIANGLSVARLCDAAIGDSDNTAANLLLRELGGP +GTVTRFARSLGDGVTRLDRWEPELNSAEPGRVTDTTSPAAIARDYARLVLGNVLEPGDRE +RLTGWLLNCRTSGTRFRAGLPVEWTVADKTGGGSYASCNDVGIAWTPEGAPVVLAVLTTK +PDGDAAGDHPLVRDAAKALA--- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf89 TaxID=1736245 RepID=UPI0006FE6BB5 +----GAALARIAGDLGGRAGIAVLDTGGGPAL-LHDAEGAFPLCSTFKLLLAAAILARVE +AGRERLDRRLAYGEADLDTYAPVTTRALRAGMSVEALCAAALVWSDNTAANLLLAALGGP +AALTAYGRDLGDPVTRLDRTEPDLNSAVPGDPRDTTRPAAMAATVGKILLGPSLTEASRA +RLEGWMTASRTGTKRLRAGLPADWGVGDKTGSGAYSTANVVALLRPPARAPLVAAIYLTG +SDTTSEARDAAHAAIGRVIAATy +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. MBT27 TaxID=1488356 RepID=UPI0014236504 +--DVSDALRQLEAAHDVRIGAYALDTVTGRTV-SYRGNESFPSLSTFKAMACAAVLDRAR +HEPGLLDKVVHWKASDEVANSPVTKGQGGKGMTVAELCRAAITQSDNTAGNMVLHQIGGP +QGMTRYYRSLGDPVSRLDRWEPELNDWQPGEHRDTTAPASMGRDLAKTSLGCGLAPADRD +TLNTWLRATVTGGERIRAGLPKDWTVGDKTGTTDYGSANDIAVAWPKSGHPVIIAVYTNH +AVAQAPADNAVIASTASTLV--- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium sp. AF50-3 TaxID=2293021 RepID=A0A3R6N380_9CLOT +-------FQELEEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS +--IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFTLLDGP +NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLALNLKEYATGDILSDDKKE +IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRNDIAIVTPPNKKPIFVAVLSKK +AEQDAEYDNKLIADATKIIFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. D16Q14 TaxID=1855658 RepID=UPI0009934B78 +-----TELASLEKDFGGRIGVYALDTGSGATL-GHRPNERFLMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYTQSDVLEWAPIASQHVAEGMTVSQLCDATIRYSDNTGANLLITQLGGP +KQTEKYVRSLGDNVSRMDRTEEELN--IPDGDLDTSTPLQLVTNLRRLVLDEGLDPQGRD +LLTDWLKRNTTGDQSVRAGVPAGWAVADKTGGGFKSETNDIAVIWPPGRAPIVVAVLTVP +DDPKSTKSKPTIAAATRIALKAf +>[subseq from] class A beta-lactamase n=1 Tax=Paracoccus marinus TaxID=288426 RepID=UPI00103D331E +--DLRTTISGWEQRLEGRIGVAVHDSGAGTRW-GYRQDERFLMNSTVKVPLCAAVLARVE +GGDLALDEILAVTQDDIVTHAPVTERHVGGGMTIADLCLATIDQSDNTAANLLFERLGGP +SEVTKFLRGIGDEVSRSDRLEPALNVLAKGDDRDTTTPAAMANTLEVLLTGDALPPAARA +QLADWMRPGGVTGALLRPSVPAGWDVADKSGSGDN-SRTLSAMVTPPGGAPVFISISVSD +TTADMSARNAAVADIGGAVMK-- +>[subseq from] Beta-lactamase n=15 Tax=Bacteria TaxID=2 RepID=A0A127STA5_9BACT +-----SLFQELEEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS +--IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFTLLDGP +NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLAFNLKEYVTGDILSDDKKE +IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRNDIAIVTPPNKKPIFVAVLSKK +AEQDAEYDNKLIADATKIIFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Comamonas terrae TaxID=673548 RepID=UPI00083376A9 +--ALSDELAAVEAQAQGRLGLHALDTVSGAEA-GWRSDERFPMCSTFKLLLAARVLYLAQ +KGEISLWRKIYYSPSELVPYSPATEKRAGADMTPQELCEAAVVLSDNTAANVLLDATGGP +AGLTAWLREMDDKVTRLDRNEPTLNEALAGDERDTTTPRAMLHTMQNLLLGDVFEGFGRA +LLQQWLVDSRTGDRRLRAGMPGSWKIGGKTGTGNNGTACDAIIVWPPQSEPVLVTAYLTG +SKLGAAAQEAALARAGEAVRR-- +>[subseq from] Beta-lactamase n=1 Tax=Plesiomonas shigelloides 302-73 TaxID=1315976 RepID=R8AQR8_PLESH +--ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKILSDVD +AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP +AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ +QLKTWMQDNKVADGLLRSVLPQGFQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ +TEATFDERNAAIVTIGKSIFDTf +>[subseq from] Beta-lactamase n=1 Tax=Nocardioides sp. Leaf285 TaxID=1736322 RepID=A0A0S9QC09_9ACTN +-----AAFAALEERYAARVGVVAIDTATGETL-AHRGDERFPYASTVKALAAAVLLDRTT +--PSDLERVVPVRRTDLVDYSPVVEQRVGRGLTLGAAAEAAVRVSDNTAGNIVLEAIGGP +DGLRRALRGLGDRVTDPRRTEPTLNRFEPGDDRDTTTPRALATTLRTLAVDDTLAPADRR +LLLRWMSGNETGDTLVRAGVPDDWAVADKSGSGAYAARNDVAVVTPPGRAPVVVAVLTRS +EDVDAVARDALVAAAAGVVAR-- +>[subseq from] Class A beta-lactamase n=1 Tax=Paucibacter sp. KBW04 TaxID=2153361 RepID=A0A3N7E0Q6_9BURK +--ELLARIEALQKRSGGRIGLFALNSGSRAQI-AFNADQRFAFCSSFKLLLAAAVLARVD +AGQLSLDKPIRFGSNDIVAHAPITSARLVNGMSVGELCEAIVTVSDNPAANLLFPLVGGP +PGLTRFLRELGDQHTRSDRIELALNTNLVGDERDTTTPAAFVASMEALLLGNRLSEEAVH +LLLGWMVGSTTGLQRLRAGLPEGWRAGDKTGSGANGAVNDVAIFWKPEQAPLLMAVFMTG +SEQSVDELNAIHAELAGLVVK-- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter sp. DsW_063 TaxID=1514894 RepID=A0A252C307_9PROT +------AIGTYERESGGHIGVYAENLATGGKL-LWRADERFVMCSTFKASLAACVLRRVE +RGQEKLDRNVAYTKADVPDYAPVAKEKLARGMTVAEMCRAAVEQSDNTCATLLLSSVGGP +AALTAFWRSIGDTQTRLDDPEPYLNRTPLGGVRDTTTPEAMAKVLQRVVLGDVLSDSSRA +LLTGWLVGCQTGGNRLRAGLPKTWRVGDKTGNNAKDAAGDIAVLWPKPDAPIIVAVYTRG +GAPTDAQLTAAFSGVGALVAK-- +>[subseq from] Beta-lactamase n=2 Tax=Halomonas taeanensis TaxID=284577 RepID=A0A1G7P806_9GAMM +-sDLNQRLAELERAADDRVGVALMNVTTGAVA-SHRGHERFLFNSTGKFFIAAAVLARVD +EGSETLDRRIVVEKGDLVGWTPITEKRLGEPLTVAELCQAAVAWSDNAAANALIESVGGP +EAVTAFLRAIGDDTTRLDRVEPDLNTDHEGDERDTTTPLAMMVTLRTLLLGDALSPSSRH +QLAAWMIEGKVGDARLRAGMPSSWLVGEKTGTNGVGNASDIGIGWPGDRGAVIAVAYTLM +PSATKTQRDDTIAAVGRLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudoalteromonas denitrificans DSM 6059 TaxID=1123010 RepID=A0A1I1NV19_9GAMM +---IIKKIEEQERQLGARIGVSIYDVTDNKLW-HYNGNTRFPLMSTFKVLACAKLLFDVE +KGLQSFDTSTVITKNSLIEWSPVTKNMIGEKISLKQACSATMSMSDNTAANIVLNGIKGP +KVLTRFMRSIGDDVTRLDRIEPDLNEALDGDKRDTTTPNAMVKSLHTLLFGDALSQASKT +QLKQWMIDNKVTGKLLRKVLPQNWSIADRSGSGGYGSRGITAVVWSDKRTPLIISIYLTQ +TEASFSQRNKAIANIGKEIFTVy +>[subseq from] Beta-lactamase n=1 Tax=Afipia sp. GAS231 TaxID=1882747 RepID=A0A1G9ZS41_9BRAD +-------LAAYERDTGGRIGVYAENLSTGAKI-AWRAEERFVMCSTFKASLAAFVLARVD +NAEDRLEDMVAYGAKDLLDYAPVAKQNLAQGMSVADMCKAIVELSDNTCANLLLARVGGP +AALTEFWSRTGDAVSRLDHNEPELNRSPPGDPRDTTTPSAMAGNLRRFLLGTVLTPSSRE +HLTQWMVDCKTGNNRLRGGLPADWKIGDKTGNNGKDASGDIAIAWPKSGGPVLVTAYTQG +GSPTPPQLETVFKEIGAMVAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=Q9REJ2_VIBHA +--------PRLKKHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD +NEKLDKNATAKVEERNMVVWSPVMDRMASQTTRIEHACEAAMLMSDNTAANIVLRSIGGP +RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQVSQLILDEy +>[subseq from] Beta-lactamase n=1 Tax=Salinisphaera sp. Q1T1-3 TaxID=2321229 RepID=A0A3A5JCB6_9GAMM +----VARLAALEKANGGRLGVAILDTAAGHRY-GYRADERFLMCSTFKLLLVAAVLQRVD +RGLERLDRRVVFDQSAILDWAPVTGLNVGAPMNIAELCEAATLMSDNTAANLLLDTLGGP +AGFTAFVRTLGDERTRLDHREPLNNR--QEGAQDTTTPAAMLGAMRSVLLGETLSDAARQ +RLLGWLRLNQTGAQALRAGLPANWSVGDKTGSASN-ANNDIAIVWPPGRKPLLVTAYYVA +ETQDTSARKRVLADVGRIVA--- +>[subseq from] Beta-lactamase n=9 Tax=Clostridiales TaxID=186802 RepID=A0A0E2H6V7_9FIRM +-------FQELEEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS +--IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFTLLDGP +NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLALNLKEYATGDILSDDKKE +IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRNDIAIVTPPNKKPIFVAVLSKK +AEQDAEYDNKLIADATKIIFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075F0715 +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNAVGPGDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000925DF2B +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDNTGSGDYGT----------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. Root135 TaxID=1736457 RepID=A0A0T1WK35_9MYCO +---VADGIVALENRFDAFVGVWAADLDNGRQV-ANRADDPFAMCSTFKAYAAGRVLQKDQ +AGALHLTDAVTIEAGDLVENSPITETRVGQNMTIGELCEATLQRSDNTAGNWLLRIIGGP +SAVTTFARTIGDDRTRLDRWETDVNSAVPGDPRDTSSPRALGAGYQRLLTGDVLDAPHRD +QLERWMRGNQT--SSLRAGLPEGWTSADKTGGGSYGSTNDVGVVYGPDGRRALLSIMTRS +RTPDAHDLRSLVAEVTTLVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075F74E4 +--AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVAMIDTLQRLLLGNTLPEPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTADVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A4S3HUL4_BURCE +--AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVAMIDTLQRLVLGNTLPEPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTADVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Leo121 TaxID=1571195 RepID=A0A4Q7G4U6_9BRAD +-------FEAYERETGGRIGLYAEDVATGAKV-TWRSGERFVMCSTFKASLAACVLARID +RGEDQLENVVRYRAADLLHHAPAARQNLASGMSVADMCKAVVELSDNTCANLLLARIGGP +AALTAFWRDTGDTVSRLDHYELELNRSPPGDPHDTTTPAAMAGNLRHFVLGEVLSPASRE +RLTGWMLNCKTGNNRLRGGLPKDWKIGDKTGNNGKDAAGDIAVVWPRKGGPVLISAYTQG +GSPTAQQLEAVFVAIGQM----- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia metallica TaxID=488729 RepID=A0A1B4I4F3_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTSFARESGATSFRLDHWEPELNNAAPGDERDTSTPVEMADTLQRLLLGNTLQEPQRA +QLTAWMAGGARGTTGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Uncharacterized protein n=1 Tax=Rhizobium sp. AAP116 TaxID=1523429 RepID=A0A0N1AJV1_9RHIZ +-----AAAKRVEQKLGMRVGLSVIDTGSGAVV-AYRDDERFAMASTFKSLACAAALSGGD +---AVLEQTTRITKADLRPHSPVTETRVGTSLSTRELCEITLRTSDNAAANAILKVLGGP +AEVTAFLRGIGDATTRLDRYEPEVNEAKPGDPRDTTTPQAMAQTLQVLLVGDALAPAARD +QLEAWMAANAVAGGLLRAKLPSGWTIADRGGAGGHGTRGVVALLRPPQGAPLVIAIYMDG +RKHPLKTRDAAIAEIGEAVFEEf +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium dioxanotrophicus TaxID=482462 RepID=A0A1Y0C6R4_9MYCO +-----DQIAGLEKRNNALIGVFAANLDSDRTV-AHRADETFAVCSTFKGYAAGRVLQLVD +RGQLALDTRIFIDPSAIVANSPVTEERTGADMSIGELCQAALQHSDNTAGNLLLKMIDGP +PGITAFARSIGDDRTRLDRWETALNSAIPGDPRDTSTPAALGAGYRALLAGDVLSPPQRQ +QLEDWMRGNET--SSLRAGLPAGWTSADKTGSGDYGSTNDVGLAYGPDGQRLLLAVMTRS +RADDPKA---------------- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LFA6_STEMA +-----ADLAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSIPRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG +TSVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SC45_9BACT +-----SLFQELEEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS +--IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFTLLDGP +NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLAFNLKEYVTGDILSDDKKE +IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRNDIAIVTPPNKKPIFVAVLSKK +AEQDAEYDNKLIADATKIIFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces himastatinicus TaxID=998084 RepID=UPI000A309EAA +--DVTRQLRALEEEYAARLGVFAFDPATGATV-AYRAEERFPMCSVFKALAAAAVLRDLD +RDGEFLAKRVHYTEEFVRKYAPVTGKNIAGGLTVEQLCAAAVSESDNAAGNLLLHDLGGP +TAITRFCRSLGDGTTRLDRWEPELNTAEPWRDTDTTSPGAIGKTFARLVLGRALTPEDRK +RLTGWLVANTTNIERFRKGLPADWILADKTGGGQYGVANDVGVVWPPERTPLVLSVLSTK +YDPQGPTDNPLVARAAALVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium iranicum TaxID=912594 RepID=A0A178LTZ4_9MYCO +---IEERIEALAKRHNAQIGLYAVNLDNEESL-GYRDSEVFAMCSTFKAYAAAAVLERAQ +QGRLALSDTVPIEATDIRPHSPVTEPRVGTAMTLAELCQAALQQSDNAAANGLLRALGGP +PAITEFARSIGDDRSRLDRWEVELNSAVPGDPRDTSTPRALGVGYRAMLTGDVLQPAGRQ +QLVDWMLGNQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVVYGPAGQRMLLAIMTRS +AVPDAASLRPLIGELATLVL--- +>[subseq from] Beta-lactamase n=2 Tax=Rhodobacteraceae TaxID=31989 RepID=A0A327LW87_9RHOB +-eTLEQTVDQIETKLDGRIGISLIDTGSDFTW-SHRQDERFLMNSTVKVPLCGAVLARVD +AGTLSLSDQLPVTQGDIQSYAPVTEQRVGQSMSIGELCMAAIDMSDNTAANLLIDHLGGP +QAITQFFRNTGDIESRLDRQEPELNTFAPGDPRDTTTPVASTDTLHTLLLGDALSDRSRK +QLADWMSHGGVTGQLLRAEAPAEWQIYDKSGSGSH-NRNLVVMVTPESRAPWVVTIFLSD +MDEDFETLNAALQDISRAVT--- +>[subseq from] Class A beta-lactamase n=2 Tax=Burkholderia TaxID=32008 RepID=A0A0G3YND6_9BURK +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS +LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTAFARASGDMSFRLDRWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRT +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodovulum sulfidophilum TaxID=35806 RepID=A0A1Q9QST3_RHOSU +--TLADTVERVESRLGARVGVSLVDTGSGLSW-THRENERFLMNSTMKVPLCGAVLASRD +AGDLSLQTELPVRKSDLLAYAPVTEKRAGGEMTIAELCLAAIDMSDNTAANLLIAHLGGP +QAVTRFFRSAGDTISRLDRNEPELNTFNAADLRDTTTPAAMTETLRGLLLGDVLSRSSRG +QLAEWMSHGGVTGNLLRAEAPEGWVILDKSGSGTH-TRNLVALVTPVDGSPWIVTIFVSD +VDADSQTRNRALQDVGRAAM--- +>[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea fuscirosea TaxID=1291556 RepID=A0A2T0NBD4_9ACTN +--QVKKELRALEASFKGRIGAYAIDTASGRTL-AYRSGERFPLLSTFKAMACAAALHRAR +TQPGLMDKVVKWTAADLKPNSPTTEKHVKDGLTVAKLCRAAITLSDNTAGNMVLKQIGGP +AGLTRYFRTLKDPVSRLDRWETELNDWAPKDRRDTTTPAAIARDLRAVTTGGALSAKDRE +RLNGWLIATETGGARIRAGLPKSWTVGDKTGTNTIGAGNDIAVAWPAGRAPIILAVYTNR +EGSGAVTNDAAIARAATILA--- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. THAF12 TaxID=2587849 RepID=A0A5P9HFQ6_9GAMM +--DLERQLGELERSADDRVGVALMNVASGAVA-SHRGHERFLFNSTGKCFIAAAVLSRVD +EGRETLDRRIVIDEGDLVGWTPITEKRLGEPLTVAELCQAAVAWSDNAAANALIESVGGP +EAVTAFLRAIGDDTTRLDRVEPALNTDHAGDERDTTTPLAMMATLRTLLLGDALSPSSRH +QLASWMIEGKVGDARLRAGLPSSWLVGEKTGTNGVGNASDIGIAWPGDRGAVIAVAYTFM +PNATGAERDETIAAVGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nesterenkonia sp. NBAIMH1 TaxID=2600320 RepID=UPI0011B78FF1 +--AVAESFEELESRYDARLGVYAVDTGTGDEV-AWRDEERFAYTSTIKAIAAGALLDQVG +--LEGLETEVPIQESDMVPHAPVTENHVGQTLTLGEIAEAAVTVSDNPAANYLFDEFGGP +AEFDAVLEELGDDVTEVVRREPDLNEAAPGDDRDTTTPRAISENLQEYLFGTTLNDEEKS +QLRQWMIDSETGDTLIRADLPSEWTIGDKSGGGGYGSRGNIAAIWPAEGDPIVIAVLSSR +DEPDAEHDDRLIAEAAEAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Amel2xB2 TaxID=1305829 RepID=UPI000DBACCA9 +--EVARGLRKLERQHSARVGVFARNMRTGTTL-VHRADERFPLCSTWKPLAVAAVLAGRG +GGEALLDARVRYSEDDLEEHSPVTGEHLDHGMTLGQLCDAAVRQSDNTAANLLLRQLDGP +AGVTRFCRSLDDRVTRLDRWETELNSAEPGRTEDTTSPRAVARTYARLVLGDALEPPQRR +RLTDWLKRNTTGDDSLRAGLPEGWSIGEKTGSGAYGTNNDVGVAWAGDRTPVILAVYTTK +HSAGAEPDYPLIAAATRLL---- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium wolinskyi TaxID=59750 RepID=A0A1X2EWI3_9MYCO +---VDDQIGELERRHNAVIGIHAVNLDSNRIV-SHRADDMFAMCSTFKAYAAGRVLQMVG +RDQLSLDNRVFVDPDAIVMNSPITEPRAGSEMTLGELCAAALQRSDNTAGNLLLKTIDGP +AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAIGYRALLVGDALSPPQRR +QLEDWMRANQT--SSMRAGLPAGWTTADKTGSGDYGSTNDVGVAYGPAGQRLLLAMMTRS +QTDDPKAANPLIGELT------- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides franklinii TaxID=948102 RepID=UPI0009947446 +---KSTELASLEKDFGGRLGVHALDTGSGDTL-SHRANERFIMCSTVKTFIVSAVLHRRL +SEPGLLDKRIQYTQADIMEWAPIASQHVDEGMTIAELCDATIRYSDNTGANLLIAELGGP +KETEKYVRSLGDNVSRMDRIEEDLN--IPDGDLDTSTPLQLATNLRRLALDEGLDAQGRD +LLTDWLKRNTTGDQSVRAGVPAGWTVGDKTGGGFKGETNDIAVIWPPGRAPIVVTVLAIP +EDPKSTKGKPTIAAATRIALKAf +>[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI0012618419 +--ALSAQVKSVENTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD +AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP +AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ +QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSVQQEPMFVSIYLTQ +TEASFDERNAAIVTIGKSIFDTf +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=BLAF_MYCFO +---IDDQLAELERRDNVLIGLYAANLQSGRRI-THRLDEMFAMCSTFKGYAAARVLQMAE +HGEISLDNRVFVDADALVPNSPVTEARAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTAAALAVGYRAILAGDALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS +QAHDAENLRPLIGELTALV---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. BMG51109 TaxID=1056816 RepID=UPI000464B05B +----GERFAGLESRRGVRLGVFAVN-GRGDRV-GYRQDERFAFASSFKALACGALLREHP +LDTGYFDRVVRYAGEELVANSPVTRDHVNSGMTVDELCLAAITRSDNTAGNQLLKLLGGP +PALTEFLRSIGDEKTRSDRWEIELNTAVPGDDRDTTTPAALAADYRALTVGNILGPAERD +RLNSWLVMNTTGGQRIRAGVPADWRVGDKTGTGEYGSAVDVAVAWTGRGEPVVIALLSTK +PDRHAEADDELLAEATRIVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces tsukubensis TaxID=83656 RepID=A0A1V4AA68_9ACTN +-----GRLGALEKEYGARLGVFALDTASGATV-SYRADERFPMCSVFKALAAAAVLRDVD +RHCEFLTRRIHYTEEFVTDYIPVTGRNIAHGMTGAQLCAAAVSESDNGAGNLLLRELGGP +AAITRFCRSVGDGTTRLDRWEPELNSAEPWRAEDTTSPRAVGKTFGRLLVGGALAPDDRE +RLQDWLIANTTNTERFRKGLPADWVLADKTGGGEYGVANDVGVVRPPGRAPLVLSILSTK +YDPQGPTDNPLVARAAALVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D00F21D +--SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0006C7C6B5 +--SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMDVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIAMAVSYTQ +PRADAAPRNDVIASAARIVAN-- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=unclassified Vibrio TaxID=2614977 RepID=UPI001372CDDD +--RVEQEVRSIEEQLSARIGVAVFNTETDEHW-NYRGEERFPLTSTFKTIACAKLLHDSE +QGDIDPLSKVKIEENDLVTYSPIIEQYVGQEITLDDACQATMSTSDNTAANMIIKAVGGT +ESITSFIRAMGDEVTRLDRIEPDLNQGLLNDLRDTTTPNAMVITLHELLFGSVLSESSQQ +KLLMWMINNQVTDNLLRSVLPNGWGIGDRSGAGGFGARSITAIVWSKTQSPIIISIYIAQ +TEASIEQRNQAIVKIGKAIFDNy +>[subseq from] class A beta-lactamase n=1 Tax=Kribbella amoyensis TaxID=996641 RepID=UPI0011A82A7F +----HDQLLALERKYGARLGVYAVATGTGRTL-AHRADERFAFCSTFKGLAAAGVLHHNP +--LTHLDTVVTYTTDDLMKSSVITRQHVRTGMTLRQLCDAAVRYSDGTAGNLLLRELGGP +AALTAYLRTLGDQVTRMDRYEPHIVTAIPGDPRDTTTPRAIGTTYQNLVVGKALAPEKQA +HLRDLLERNATGRRRIRAGLPKSWTVADKTGTGDYGTTNDIALTWPPQAPPLLIAILSSK +PQEQAPSTSALLAEAATYT---- +>[subseq from] Class A beta-lactamase n=1 Tax=Photobacterium damselae subsp. damselae TaxID=85581 RepID=A0A5N4FP62_PHODD +--ALVNIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KDKSVLTHQVVIKKSDLVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDPRDTTTPVAIVETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTQHKPMVMSIYIQQ +SSASMDERNKAIAIIGKQVFTYf +>[subseq from] Beta-lactamase n=1 Tax=Jiangella alba TaxID=561176 RepID=A0A1H5PI30_9ACTN +---VAAALTALEDDYAARLGVYAIDTGSGQIV-EHRPDERFAFASTHKMLSAAAVLQATE +--PADLDQLIEVDAAEVVGWSPVTEPAAGVGLTLLEIIEAAITLSDNTAANLLFEQLGGP +DGLEAAVRGFGDTTTSFDRIEPGLSDWVPGEERDTTTPRAMAGNVQDLLLGDLLADEDRT +LLHDTMRANTTGDELIRAGVPDGWVVADKTGSATHGGRNDVAVIEPPGAAPIVLAVYSNR +LDPEAESDPALIAAATEIVVDE- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia multivorans TaxID=87883 RepID=B9BHK2_9BURK +--RAQAELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNAVGPGDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSLTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI0014281F3E +-sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLVGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNAILNTLRTLVEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLVAQISQLILQKy +>[subseq from] class A beta-lactamase n=1 Tax=Atlantibacter hermannii TaxID=565 RepID=UPI0005C12D8D +---MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ +KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP +DAVTQFMRGIGDHVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTAPPLTPDNRA +TLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ +TEASMKMANEAIAEIGKQLF--- +>[subseq from] Beta-lactamase n=1 Tax=Lentzea albidocapillata TaxID=40571 RepID=A0A1W2FGS2_9PSEU +--TVTGKLRELEKRHNARLGLFATDTGTGRTV-LHRADEIFPMCSTFKTIAAAAILRKDR +-DGTLLGKVITYTQSDVDKWGPETGKNLANGMTVSALCEATITYSDNCAANLLLRELGGP +TAISRFSRSIGDPVTRLDRWEPELNSAEPGRITDTTSPRAIGQSYARLTLGHALNSNDSD +QLTKWLLANTTGGNRIRAGLPSAWRWGDKTGTGSYGTTNDVGIAFPAGRAPIVIAVLSTR +KDPTGGADEPLLAKTAELVAATf +>[subseq from] Beta-lactamase n=1 Tax=Oleispira antarctica RB-8 TaxID=698738 RepID=R4YSQ0_OLEAN +-----EKIKQVESELSARVGVSVYDVSSKQLW-DYDGDVRFPLMSTFKTLACAKLLSDVD +NGDQSFDSSVVIKDSSLITWSPVTKKHVGESFSLKQACSAAMIMSDNTAANIVLDGINGP +SALTKFMRSIGDEVTRLDRIEPYLNEAIDGDVRDTTTPNAIVKSLHELLFGNALSESSKN +QLKMWMMDNKVSDSLLRSSLPNDWSIADRSGAGGYGSRGITAVVWSGKRTPLIISIYLTQ +TDASFDERNKAIAGIGKEIFTFy +>[subseq from] Beta-lactamase class A n=1 Tax=Klenkia taihuensis TaxID=1225127 RepID=A0A1I1QXC5_9ACTN +-------VDALEATYGARVGVWALDTGTGRVV-EHRAGERFAHASTLKLLLTGLLLDRVS +--DAELDAVVPIAADDVLEYAPVTSQHVGTGLPLREVMAAATTVSDNTAANLLVEQLGGP +AQVQAALRELGNPTTRVDRVEPELNEATPGDPRDTSTPADLGASVQQLVLGDVLAPDRRA +LLQQWLRDSTTGDAAIRAGVPDGWEVGDKTGSGGYGTRNDVGVVEPDDGAPLVVVLLTDR +GVPDADTDDALLADATRLVVDQ- +>[subseq from] Beta-lactamase class A n=2 Tax=Rhizobium sp. RU33A TaxID=1907413 RepID=A0A1N6SY11_9RHIZ +-----AAAKRVEQKLGMRVGLSVIDTGSGAVV-AYRDDERFAMASTFKSLACAAALSGGD +---AVLEQTTRITKADLRPYSPVTETRVGTSLSTRELCEITLRTSDNAAANAILKVLGGP +AEVTGFLRGIGDATTRLDRYEPEVNEAKPGDPRDTTTPQAMAQTLQGLLVGDALAPAARD +QLDAWMTANAVADGLLRSKLPKSWTIADRSGAGGHGTRGVIAVVRPPKGAPLVVAIYMDG +KAHPLKTRDAAIAEIGEAVFADf +>[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis excentricus (strain ATCC 15261 / DSM 4724 / VKM B-1370 / CB 48) TaxID=573065 RepID=E8RLQ3_ASTEC +----GQRLMEIQKRHGGRVGVSVRDTAADGSL-NINSSERFALCSTFKWVLATAVLKAVD +DGKLSVTQEIRYSKADLLDHSPVTEKHVPKGLTVGDLCSAAVAVSDNAAANLLLPLIGGP +AGLTAFVRGLGDMVTRLDRNEPELNSNIEGDERDTTTPDAMSSLLRNVFTGAVLQPKSLS +LLRDWMVATVTGPDMSPAGVPKGWTVGHKTGRGANGAVNDVAVIWPSGELPIFLSIYTTG +GTLDDKARNAVVADITRLVID-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. E136 TaxID=1834125 RepID=A0A1A2MDL4_9MYCO +--QLAGRLAEMERSHNALIGVFAVNLDTRRTV-AHRAQDPFSLCSTFKTYAAARVLQRAE +RGELALTDRVTVEQGDIVPNSPVTGEHIGQTMTLAELCQAALQQSDNAAGNLLLRTIGGP +SGVTDFARSIGDQRTRLDRWEIELNAAVPGDPRDTTTPEALGGGYRSLITGNVLGEPQRR +QLDDWMRANRT--STVRPVLPPGWTIADKTGSGDYASTNDVGVAFGPAGERLLLAIMTRT +AAPDVPNDRQMVGDVGSMLVA-- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. ND22Bw TaxID=2054178 RepID=A0A2P7PBE4_9GAMM +--DLERQLGELERSADDRVGVALMNVATGAVA-SHRGHERFLFNSTGKFFIAAAVLARVD +EGRETLDRRIVIEEGDLVGWTPITEKRLGEPLTVAELCQAAVAWSDNAAANALIESVGGP +EAVTAFLRAIGDDTTRLDRVEPELNTDHAGDERDTTTPLAMMATLRILLLGDALSPSSRH +QLAAWMIEGKVGDARLRAGMPSSWLVGEKTGTNGVGNASDIGIAWPGDRGAVIAVAYTLM +PNATGAERDDTVAAVGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Kineococcus sp. T13 TaxID=2696565 RepID=UPI001412686C +--EAAERFAQLEQRFDARLGLFAVDTGSGEVV-THRADERFAFASTYKALAAAAVLDRTT +--DAELDGVVTWEAGDLVDHSPVTGDHVATGLPLRAVAEAAITVSDNTAANLLLERLGGP +QALEQELRALGDGATEVDSTEPEVNDHVPGETQDTSTPRAMATSLRAYAVGDALEAGDRE +QLVEWLRANTTGGEQVRAGVPAGWVVGDKTGHAGYGNQNDIAVVWPADRAPWVLTVLTDR +TGVDDESDDALLAEATRVVVQQ- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodovulum sulfidophilum TaxID=35806 RepID=UPI0005AB0F31 +--TLADTVERVESRLGARIGVSLVDTGSGLSW-THRENERFLMNSTMKVPLCGAVLARRD +AGDLSLQTELPVRKSDLLAYAPVTEKRAGGEMTIAELCLAAIDMSDNTAANLLLAHLGGP +QAVTRFFRSAGDTISRLDRNEPELNTFNAADLRDTTTPAAMTEALRGLLLGDVLSRSSRG +QLAEWMSHGGVTGNLLRAEAPEGWVILDKSGSGTH-TRNLVALVTPVDGSPWIVTIFVSD +VDADSQTRNRALQDVGRAAM--- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Methylobacterium TaxID=2615210 RepID=A0A5C8VMQ5_9RHIZ +-----GRIGAVEVRLGGRVGVAFHD-ATGVFL-GHRADEAFALCSTFKVLAAAAILARVA +AGRETLDRRIAYGADDLQSYAPVTRSRAGGGMTVDGLCAAAIVRSDNTAANLLLDALGGT +AALTAWLRGQGDAVTRLDRTEPTLNTALPGDPRDTTSPAAITRTLDRCLLGDALAPPHRA +RLEAWMVACETGGAKLRAGLPPAWPVGDKTGSGDNATSNVVAILHPPGRAPILAGVFLTG +SEAPPAARDAAHAEIGRILAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. A2 TaxID=236253 RepID=UPI00084BE6F2 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGA +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMSVLGGP +QAVTAFARECGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDVLREPQRA +QLTEWMVGGARGATGIAAGVSPGWRVADKAGTGGFGTTTDVAVLWPPSHAPIVMAVSFTQ +PDAAAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=A0A1S1LTY7_MYCCH +--------TALEDWYGARIGVYAVDLDSLRTV-EHRADERFSMCSTFKTYAAARILQLSD +AGAADLDTKIPIARDDVVVDSPITRDAIGSSMSLGDICAAAMMHSDNTAGNIVLRTIGGP +AAITAFARSIGDTHSRLDRWEPDLNTAIPADPRDTTTPKALCTGYRRILTADVLATPARD +RLLTWMKSNVTSSKRFRAGLPPDWTSADKTGAGDYGSTNDAGLLIGPDGQRVVAVVMTRS +RDHDAPPFNEAIAGAIRV----- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. ZAC14D2_NAIMI4_6 TaxID=2072406 RepID=A0A3Q8F9B4_9GAMM +------DFAALEKASGGRLGVTVLDTGSGRRLgGHRQDERFPMCSTFKSMLVAHILSLAD +AGRLSLDTRVPIAEQDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP +AALTAFLRAQGDPITRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGAGLLPPSRL +QFADWLVDNQTGDACLRAGLGPRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG +ASVDEAQRAAVLARVGAL----- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2L1J139_KLEPN +-----------ERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDI------------------- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudonocardiaceae bacterium YIM PH 21723 TaxID=2340915 RepID=A0A419HJ22_9PSEU +-----PRLTELEKKYGARLGVYAEVIGTSRML-EFRADDRFAFCSTFKALATAALLRAHP +--LSYLDTRVRFAESDLMKHAPITRSHVDTGMTLRELADAAIRFSDGTAGNVILREIGGP +GMLTQYARSLGDDVTRMDHIEPVITAAVPGDPHDTSSPRAFGTSLRKIVAGDALPEDRRA +FLRDLLERTETGKDRIRAGVPAGWRVADKTGTGDYGTLNDIAIVWPPDRPPLLISIMSSK +PAQDAEYQPALLADAARYVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0011ADFEA1 +--AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVAMIDTLQRLLLGNTLPEPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Alteromonas facilis TaxID=2048004 RepID=UPI000C28E48B +---LSEKLRAIENETGGILGVAVLDTESQHLW-HYNGDLRFPMMSTFKTLACAKMLHDHD +KSLIDSATEYPVIKAELVVWSPITKDLVGQSISLFDACEATMLTSDNTAANIALKQIGGP +PAVTQFLRTYGDPTTRIDRYEPELNQAVAHDPRDTTTPKAMTETLSTLLLGTTLSKTSAQ +QLKQWMQNNTISDALLRSVLPSAWQIADRTGAGENGSRGITAIIWNSSRPPIILSIYLTQ +TQLSLSERNAVIAEIGNAVFHHy +>[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas sp. KH9 TaxID=1855324 RepID=UPI000B7D9C3B +---LTVALADVEARHGVRLGLHALDTAQGRTV-SHRADERFAFCSTVKPLAAAAVLAS-- +RGVGGLDEAVPVTADDLVTYSPVAETRVGVGMTWRELGDAAVRYSDNTAGNLLLRGAGGP +EGLTAWLRGVGDDVTRSDRWEPDLNAFTPGDERDTSTPRALAGTYGALVVGEVLAPPERD +VLTDWLVRNTTGDALVRAAARPGWTVGDKTGSGAYGTRNDVAVVWPPDGAAVVLAICTDQ +AVPDADTVDAPLAEAARVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3Z8XPW5_ECOLX +---MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ +KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP +DAVTQFMRGIGDHVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTAPPLTPANRA +VLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ +TEASMKMANETIAEIGKQLF--- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea polychroma TaxID=46176 RepID=A0A438MBD6_9ACTN +---VKKELRALEKAFNGRIGAYAVDTATGKTV-TYRAGERFPLLSTFKAFACAAVLHKAR +TDPGLMNKVMHWTADELLEHSPVTEKHVKDGLTVAQLCEATITVSDNTAGNLILKEIGGP +AGLTKYFRSLKDAISRLDRYEPGLNDWTPKDKRDTTTPAAIARDLRVLTIGNALHAKDRE +QFNAWLIATKTGDARIRAGLPKTWTIGDKTGTNSTGGGNDIAVIWPEKGAPLIMAIYTNR +SP-GLATDDKTIAKTATILA--- +>[subseq from] Beta-lactamase n=1 Tax=Actinobacteria bacterium OK006 TaxID=1592326 RepID=A0A0N0MWU7_9ACTN +---------------------------------RHRAAERFPLCSVFKTLAAAAVLRDLD +RHGETLARRIHYTAADLAGYSPKTGEHLASGMTVGELCDAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PAQDAAPDSPLVAAAASLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC 06783 TaxID=2203211 RepID=A0A429I3M8_9ACTN +----VRRLRALEGEHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD +HDGSQLARVIRYTEADVTKHAPVTKDHIDTGMTIRDLCDATIRYSDNCAANLLLRELGGP +TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA +LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGGYGTRNEAAIAWTPDGAPVLLTALTHK +PSPTAPGDTPLIIKLATV----- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. C35 TaxID=2126993 RepID=UPI000D699E54 +---AQERFQKLEQRSEGRLGVAALNTADGSYV-GYRESERFPMCSTFKLVATAWVLKRSM +AERGLLDERVRFGEADLVANSPITRRHVREGMSIGELCAAALQYSDNTAANLLLTALGGS +EVLNEFARGIGDEWFNLVRVETEVNASVPGDMRDTTSPRAMMLDVQKFLLDEVLGLQQRE +QLKTWMLGNTTGAARIRAAVPSGWRVADKTGSGDYGTANDVAVVYPPAAEPLVLAVYFTG +VTRETLPRDEIVVEAARVVFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides franklinii TaxID=948102 RepID=UPI0013E8F23D +--ALSPHFAALEQEFAGRLGVYALDTGSGTAL-GNRQSERFLMCSTVKVFIVSAILTRRR +TEPGLLEKRIHYTNADILDWAPVTPAHIADGMTVEELCAAAVSHSDNTAANLLIAELGGP +EETEKFVRSIGDSTTNTDRTETDLD--IPDGDKDTSTPEQLVSNLRTLVLGDALDREGRD +KLIGWMKANTTGDQSIRAGVPHGWEVGDKTGSGSRGESNDIAVIWPPNRAPILLAVLTAP +DDPTSTKGKLTIAQATRQAI--- +>[subseq from] Beta-lactamase n=1 Tax=Atlantibacter hermannii TaxID=565 RepID=A0A2K8GRJ1_ATLHE +----TAFLQQQEKQLNAHIGMAVVNAQGESVF-GYRQDERFPLTSTFKTLACAALLERLQ +KDGGSLDQQVTIQPDELLDYAPITKNYLAPALSLRTLCAAAVSYSDNTAGNRILAYLGGP +QAITQFMRRLGDNVTRLDRTEPTLNEAMPGDARDTSSPKSMAAGLQKILTSNTLTPANRA +TLDSWMREDKVGDALLRATLPQGWSIADKTGAGGHGSRAIIAAVYPPQQAPFYVAIYITR +TEATMPMTNTAIAQIGERLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia mexicana TaxID=279262 RepID=UPI00082D8CF4 +--AAEEHFAALERKYDARLGVYAISTGTAVSL-AYRADDRFAFCSTFKTLAAAAVLQRHP +--MSYLDTVVRYTREDVNSISPVAQDHIETGLTIRELCDAAIRFSDGTAGNLLMRDIGGP +EQLTAYLRSLGDTVGRMDQYEPELNSDPPGDPRDTITPRALAADYQQVVLRGALPPEKQA +LLKDWLQRSATGAQTIRAGVPAGWTVANKTGHGDFGRANDVAVVWPPDGAPLILAIMTDR +TGFDAAPPYPMIADAAAYLSKAf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia (strain MC0-3) TaxID=406425 RepID=B1K308_BURCC +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMTGGARAATGIAAAVPPGWRVADKAGTGGYGTTTDIAVQWPPSRAPIVMAVSFTQ +PDAAAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 852002-51961_SCH5331710 TaxID=1834105 RepID=A0A1A0RQ74_9MYCO +--QLAGRLAEMERSRNALIGVFAVNLDTGRTV-AHRAQDPFSLCSTFKTYAAARVLQRAE +RGELALTDRVTVEQGDIVPNSPVTGEHIGQMMTLAELCQAALQQSDNAAGNLLLRTIGGP +SGVTDFARSIGDQRTRLDRWEIELNAAVPGDPRDTTTPEALGDGYRSLITGNVLGEPQRR +QLDDWMRANRT--SSVRPVLPPGWTIADKTGSGDYASTNDVGVAFGPAGERLLLAIMTRT +AAPDVPNDRQMVGDVGSMLVA-- +>[subseq from] Beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=A0A2P1VMM6_PLESH +--ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD +AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP +AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPDAINHTLNTLVLGETLSSTSRQ +QLKTWMQDNKVADGLLRSVLPQGFQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ +TEATFDERNAAIVTIGKSIFDTf +>[subseq from] Beta-lactamase n=12 Tax=Enterobacteriaceae TaxID=543 RepID=A0A3L4MDJ0_ECOLX +---MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ +KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP +DAVTQFMRGIGDHVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTAPPLTPANRA +VLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ +TEASMKMANETIAEIGKQLF--- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC201 TaxID=1848320 RepID=A0A4R4NID0_9ACTN +--QVKKDLRGLEVSFKGRIGAYALDTATGKTV-TYRAGERFPMLSTFKAPLCAAVLRKAR +TKPGLMNRLIKWTAADMKPNSPVTEKHVKDGLTVSQLCEAAVTMSDGTASNLLLKQVGGP +KGLTRYFRTLKDATSRMDRWHPELNDWTPKDKRDTTTPAAIGRDLRVLTVGRALHAKDRR +QLLAWLLANKTGGERIRAGLPKSWTVADKTGTNSFGGGNDIAVVWPKRGAPVIMSIYTNR +TK-GLPTDNKTIAKTATILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI00126248E8 +--ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD +AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP +AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHSLNTLVLGETLSSTSRQ +QLKTWMQDNKVADGLLRSVLPQGFQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ +TEATFDERNAAIVTIGKSVFDTf +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. Soil538 TaxID=1736391 RepID=A0A0Q9JCP5_9MYCO +------DLKGIEHRHRARIGAYAVDLGTAATV-EHRADERFAMCSTFKAYAAGRVLQLVD +QSRLDLRTPIPVNAADIVANSPVTEQRVGATMALAEVCEAALTRSDNAAGNLLLRTIGGP +GGVTAFARTLGDEQTRLDRWETELNSAIPGDARDTTTPRGLCWGYRQLLTGTALSPSARA +TLDGWMRANVTSGPRFRAAVPTGWTTADKTGAGDYGSTNDAGLILGPTGQRVMAVVLTRS +IDKDTPPLNAAISDTVRLILDSf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0008414043 +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDRWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPTRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia GG4 TaxID=1009846 RepID=J7J7M3_BURCE +--AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCMALLQSNDKGAGNLLMGVLGGP +QAVTSFAHESGDPAFRLDRWEPELNQAAPGDLRDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWMTGGARGATGIAAGVPPGWRVADKTGAGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PSADAAARADVVASAAHIAT--- +>[subseq from] Beta-lactamase n=2 Tax=Tatlockia micdadei TaxID=451 RepID=A0A098GIU2_TATMI +--SIDKKLAKLESSSGGRIGVYAINTTNNTHL-EYRADERFPMGCTSKVMGVAAVLKKSM +KDNLLLSKKVTYTKNDLTNWNPITEKNLDTGMSVKELCAAAISYSDNTAMNLLLKQLGGL +EGMNAFARTIDDDSFRQTHGWPEAMSGGQNNTDDSSTPAAMATSLKKLAFTDALAKPQRE +LLLTWLKANTTGDARIRAGVPKGWLVGDKTGTGYYGTTNDIAIIWPPKCDPIVMAVYYTS +NNKNASKREDIVASTTRIILDE- +>[subseq from] Beta-lactamase n=1 Tax=Kosakonia arachidis TaxID=551989 RepID=A0A1I6ZR91_9ENTR +---LAEVVRLQEQQLGARIGVAVVDSARGKTV-SYRGDERFPLNSTHKALLCGALLSQVD +KGELALTETTQFPRSALVAYSPVTEKFIAPAINWQQLCSAAVSYSDNTAANLLAQKLGGP +VAITHYLQILGDSVTRLDRAEPELNSAIPGDVRDTTTPLAVSRTLQKLTLGTALKPGSRA +QLIQWMREDKVADMLLRSTLPAGWVIADKTGAGDFGSRSIISVVWPKNSTPRIVVIYITN +TKATLKQSNVAIARLGKEIF--- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia mexicana TaxID=279262 RepID=A0A370GJP1_9NOCA +--AAEEHFAALERKYDARLGVYAISTGTAVSL-AYRADDRFAFCSTFKTLAAAAVLQRHP +--MSYLDTVVRYTREDVNSISPVAQDHIETGLTIRELCDAAIRFSDGTAGNLLMRDIGGP +EQLTAYLRSLGDTVGRMDQYEPELNSDPPGDPRDTITPRALAADYQQVVLRGALPPEKQA +LLKDWLQRSATGAQTIRAGVPAGWTVANKTGHGDFGRANDVAVVWPPDGAPLILAIMTDR +TGFDAAPPYPMIADAAAYLSKAf +>[subseq from] Class A beta-lactamase n=1 Tax=Comamonas sp. TaxID=34028 RepID=A0A5N7WCV6_COMSP +-kTLGEELAALEVQAQGRLGLHVLDTVSGAEA-GWRSEERFPMCSTFKTLLAARVLYLAQ +KDEIRLWRKLYYAPSEVVAWSPVSEKRAGADMTVQQLCEAMVLVSDNTAANVLLDASGGP +AALTQWLRELGDGTTRLDRNEPSLNSALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA +LLQQWLVDSRTGDRRVRAGMPGDWKAGGKTGSGERGTACDTLIVWPTEQAPLLVTAYLTG +SALDGAGREAVMARAGEAIK--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. LS-044 TaxID=1459967 RepID=A0A4S5DDR4_9BURK +--AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVAMIDTLQRLLLGNTLPEPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTADVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Beta-lactamase class C n=1 Tax=Burkholderia sp. NFACC38-1 TaxID=1566268 RepID=A0A1H9ZXM8_9BURK +--AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVAMIDTLQRLVLGNTLPEPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTADVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI0007ED8A83 +--ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLTDVD +AGKLALKDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP +AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ +QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ +TEATFDERNAAIVTIGKSIFDTf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007553D47 +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLSRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacteraceae bacterium 0127_4 TaxID=2686094 RepID=UPI001315C956 +-----QRFAAIEARIGGRVGVAAWNTGTDAWL-GHRRNEAFAMCSTFKWALTAAVLHTAQ +RGGPQLNEIVCYNQSDMLSHAPVTSQHLERGMTVEELCAAAVITSDNPAANLLLELQFGP +EGFTRFLRANGDGVTRLDRTELALNENLPGDPRDTTTPDAMARTLKRFLLEDVLNAASRE +KLTGWMETSTTGLSRLRAGLPAGWRVGDKTGTSTHNATNDVAIAWPPGRAPIIITSYLSE +SMVELDARNAAHAEIARIIAGEw +>[subseq from] class A beta-lactamase n=2 Tax=unclassified Vibrio TaxID=2614977 RepID=UPI0013737AAD +--QLTQSVKDIESDWQGRIGVYAYDIYGSFTF-GYREQERFPLCSSFKSLLAAAILQKSQ +NQLLNLDTSIDFSERDLEFWSPITEENHAEGMSIGQLAQAALQYSDNGATNILLERIGGP +KGMNTFMKSIGDEDFRLDRWELELNTAIPGDERDTSTPKSMATSIGKLSFGNVLSASHQE +LFHDWLIGNTTGDNRIRAAVPKQWQVGDKTGTCGYGAASDVAVIWREKASPLVIAIYTHK +SEPSAKHSDKIIAEVAKETLQ-- +>[subseq from] Beta-lactamase n=1 Tax=Cellulomonas sp. KH9 TaxID=1855324 RepID=A0A1I3ZN96_9CELL +---LTVALADVEARHGVRLGLHALDTAQGRTV-SHRADERFAFCSTVKPLAAAAVLAS-- +RGVGGLDEAVPVTADDLVTYSPVAETRVGVGMTWRELGDAAVRYSDNTAGNLLLRGAGGP +EGLTAWLRGVGDDVTRSDRWEPDLNAFTPGDERDTSTPRALAGTYGALVVGEVLAPPERD +VLTDWLVRNTTGDALVRAAARPGWTVGDKTGSGAYGTRNDVAVVWPPDGAAVVLAICTDQ +AVPDADTVDAPLAEAARVVLD-- +>[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobium diazoefficiens TaxID=1355477 RepID=A0A0E4BP52_9BRAD +------ELEAYERESGGRIGLYAENLATGAKI-AWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMLPYGQADLLSYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRIDHNEPEVNKSAPGDPHDTTTPAAMAGNLRRLVTGEALSPASRA +QLTEWLVGCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWPKDTAPILIAAYTQG +GSPADRG---------------- +>[subseq from] Beta-lactamase n=2 Tax=Nocardioides sp. SLBN-172 TaxID=1813332 RepID=A0A542MV05_9ACTN +------SIAALEQKHQRHLGVWAKNMRTGRVV-EHRADERFPMLSTFKTLLVAAILRDLP +--VRTLQQRLTWEATDVVVNSPVTSLTVRNGLTVAQLAEATMTRSDNTAANELLHLIGGP +AGITSFARSLGDTVSRLDRWEPDLNSAIPGDPRDTTSPRAIARTYTKLVLGDALGGADRD +QLLTWMLANQSTVTRFGAGVPAGWRLADKTGGGDYASRNDVGVTWTPDGAPIVIAALTRS +DDPAAPPLDAPLADIAATVC--- +>[subseq from] Beta-lactamase n=1 Tax=Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054) TaxID=452652 RepID=E4N3R1_KITSK +--QIVDRLRQLERIHGARLGVFAHDTGTGTTV-HHRADERFPLCSTFKPLAVAAVLRDGH +----DLAAAVHYTDRDVADYAPVTGRT--RALTVAELCAAAIEFSDNTAANLLLRRLGGP +TAVTRLCRSLGDPVTRLDRWEPDLNSAEPDRETDTTTPSALARTFARLTLGDALPQPQRA +RLTAWLRACTTGAHRLRAGLPPSWTLADKTGTGAHGTANDLALAWPPHRPPLVLAVLSTK +PAPTATPDEPLLAATARLLAATf +>[subseq from] Beta-lactamase n=2 Tax=Actinosynnema mirum TaxID=40567 RepID=C6WEM9_ACTMD +------AFAALEQRFDARLGVYALDTGSGRVV-AHRADERFAYASTFKALAFGALLAERS +--VADLDERITFTGEELVTYSPITEGKVDTGMTLREVADAAVRHSDNTAGNLLLRELGGP +AAFERALRAIGDTTTSPARVETELNEAVPGDPRDTSTPEALAADLRRYAVADVLADDRRE +LLVSTMRANTTGDEAIRAGVPRGWVVADKTGSARYGGRNDIAVLWPPDRAPIVLAVLSGK +ATADAEHDDALLAEATRAVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Roseivivax sediminis TaxID=936889 RepID=A0A1I1SV82_9RHOB +--TLARTVGQIEGRLEARVGIALVDTGSGATW-SHRPDERFLMNSTAKVPICALVLAQRD +EGDISLSDALTVRESDLLSYAPVTSEHVGESMSMSELCLAALDMSDNTAANLVLDRAGGP +EAVTDLFRQAGDPVSRLDRREPDLNAFTPGDPRDTTTPAAMAATLRELLLGETLTVASRE +QLAAWMSHGAVTQDLLRSHAPAGWEIFDKSGSGDQ-TRNIVALVSPSNGAPWLVTIFISD +ADTDFATRNAALKDLSAAVM--- +>[subseq from] class A beta-lactamase n=1 Tax=Leifsonia aquatica TaxID=144185 RepID=UPI00046844F2 +---TQGAFSALERTHAATLGVTAIDTGTGRTV-AYRGGERFPFASSNKTFIAAATLQASS +--DADLDTVVHYTSADLLAYAPITSRFVDTGMTVRELLDAMLRFSDNTAANLLVARLGGP +DAVEAWLRGIGDRTTNVDRIEPDLNEALPGDARDTTTPAQFAADLRAVLLGSTLETKDRT +LLRNTMLDCTTGDGTIRAGVDPAWPVADKTGTGEYGVRDDIAVVYPAGRAPIVIVTMSRH +ATADAASDDALLAAATKVAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Lentzea terrae TaxID=2200761 RepID=UPI000DD37879 +-----EALFELEKKYDARLGVYAAG---VSTI-EHRADERFAFCSTFKGLATAAVLHRNP +--MQHLDTLVRYTEADLMKSSTKTRPNVQTGMTLKDLCDAAVRFSDGTAGNLLLKDLGGP +TQLTGYLRELGDTETRMDRTEPAITEATPGDPRDTTTPRAIGTAYQKIVLGDALEPAKRD +FLTDLLTRSVTGAKRIRAGVPQDWRIADKTGTGDYGTLNDIAIAWPPNREPIVISIMSSK +SQGDAKYDEALIAEAAAYVVK-- +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=A0A2T3IE66_9GAMM +--ALVNIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KDKSVLTHPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ +SSASMDERNKAIATIGKQVFTYf +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium diernhoferi TaxID=1801 RepID=A0A1Q4HAL3_9MYCO +---FEEQVRELEARYNAFIGLYAVNLESGATV-ASRADEAFALCSTFKTYAAAAVLQRVA +AGELSLEQRLFVDPAALLPNSPVTGENAGHEMTLAELSQAALQRSDNLAANLLLETLGGP +SAITAFARSIGDDRTRLDRWEIELNSAIPGDPRDTSTPRALATGYRNLLAGEALPAAQRE +LLDGWMRANQT--SSMRAGLPPGWTTADKTGSGDYGTTNDSGVAYGPDGTRLLLTIMTRT +QSADAEGLRPLIGELAAL----- +>[subseq from] Class A beta-lactamase n=2 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A2S9N1Q5_9BURK +--SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMDVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Tabrizicola sp. DJC TaxID=2305252 RepID=A0A411YXW3_9RHOB +-qRLFETIAEIEQRLNARVGILVRDSGSDWSI-SHRSNERFLMTSTFKPMLCGAVLKQAE +VGKLDLDESVWIAAKDILDYAPVTKTMVGDTMTIDDLCFAALDMSDNTATNLLIDRIGGP +EEVTSFLRDIGDPVSRLDRREPELNTFAPGNPRDTTTPEAMAATLEVMLTGTALTQQSRE +QLTEWMSHGGVTGPLIRASTPADWQVADRSGSGNF-NRNIIAMVTPPDQAPYFISVFLSD +ADADFETRNGAVIELSQAVMD-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000CD4DD07 +---ADTAFGELEQEFDARLGVYALDTGSGAEV-AHRADERFAVASTFKALAAGAVLDQYG +--LDGLNTLTAFDLDDLVSHSPVTERFAGDGMPLGDLAAAAVRQSDNTAANLLLEALGGP +SGFTEALRAVGDDVTRIDRWETELNDVPPGEERDTSTPRALSETLSTYLLGDVLDAQEKD +RLAEWMTTNTTSATLIPAGVPDSWIVADKSGGASYGIRNDIAVLWPEEGEPVLLSVLSNR +DEEADESDDALIARAATAALE-- +>[subseq from] UPI00143EDE5E UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00143EDE5E +---LDAVLADLEERRRVRLGVLAHDPGRGLTY-ARRADDRFAMCSTFKVYAAAAILRLES +QGSLRLDDTVPVDPADIVENSPVTSEAQGRTLTLAQLCDAALTRSDNTAGNLLLRRLGGP +TAVTAFARSLGDTVTTLDRWEPELNSAEPGDVRDTSTASGLARGYRELLLGSGLPAAGQQ +TLTGWMRASVTSGQRIRAGLPAGWTAADKSGAGRYGTVNDAGVLWSPDGSPLVLVLLSDS +VTPDAAHDNAAIAEATAVIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI00058DE9F5 +---LSRELRALEGRFGARLGVFARNAVTGASV-RYRAGETFPICSTFKTLATAAVLRDLD +QNGEFLAKTIRYTAQEVEDYGPITGENLAHGMSVEALCAAAVSYSDNAAANLLLRELGGP +RAVTRFCRSLGDPITRLDRWEPELNSAEPWRTTDLTTPAEVGLDYGRLVLGKALPRGDRE +LLTGWLRGNTTGDARLRAGLPEDWTVADKTGTGEYGTTNDVGIAWTGDGTPLILSVLATQ +PDPEAPAVDALIAETARLLV--- +>[subseq from] Beta-lactamase n=1 Tax=Humibacter sp. WJ7-1 TaxID=2599293 RepID=A0A5B8M9M6_9MICO +--ALSSQLSQIETRFGARVGVDVLDTGAGTTF-GYRATERFALDSTSKVLTSGMVLSEAD +--DARLATVIHFGSSELQSYSPITSQHVDTGMTLSALVAAALQYSDNTAANLLYGELGGP +AAAQSRLRAWGDTITNLDRVEPDLNSAVPGDVRDTSTPGQMATALKALLIGDRLSAQRRA +FLRDTMLANTTGGPYIRAGVPSTWRVADKTGNGGYGSRNDVAVLYPPGASPIVLTVYTTR +STADAASDDGLIATVTRSVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Kitasatospora atroaurantiaca TaxID=285545 RepID=A0A561F1Q6_9ACTN +-qTLYRQLKKLERDHSARLGVFARNMATGTTV-LYRADELFPICSVFKTLAAAAVLRDLD +QDGEFLARRIHYTQKDVTDYGPITGKNLANGMTVAQLCAAAVSDSDNAAGNILLRELGGP +TAITRFCRSIKDWTTRLDRWEPLLNSAEPWRISDTTSPRAIGTTYARLLLGDVLPPRDRE +QLTGWLIANTTNRGRFRAGLPVDWTLADKTGGGDYGVANDVGVVWPPDGPPIAMTVLTTT +LASTGPRDEPLVAKTATLLA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID11385 TaxID=2706031 RepID=A0A6B2UQ84_9ACTN +--TLVSRFRALEGEYAARLGVFALDTATGRTV-SYRADERFPMCSVFKGLAAAAVLRDLD +REGEFLAVRVRYTAEFTRTYAPVTGENLANGMTVAQLCAAAVSFSDNAAGNLLLRALGGP +TAITRFCRSLGDPTTRLDRWEPELNSAEPWRDTDTTSPRAIGRTYARLVVGRALTPGDRE +KLTGWLVANTTDDERFGSGLPADWVLADKTGGGQYGVANDVGVVWPPDRAPLVLSVLSTK +YDPAGPTDNPLVARTAALVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 1423905.2 TaxID=1856859 RepID=A0A1A3HL33_9MYCO +-----GRIDELEDQYHAIVGVYARDLASGRAV-THRADDAFAMCSTFKVYAAARVLQKCE +RGELDLAQATFIDPAALQPNSPVTAPHAGDTMPLSLLCAAALQRSDNTAANLLLQAIGGP +PAITDFARSIGDDRSRLDRWEIELNTAIPGDPRDTSTPRALGGGIEKLLTGAVLASSQRS +QLETWMRGNVT--STMRAGLPPGWTTADKTGTGDYGSTNDIGVAYGPDGRRVLLAIMTRS +QAPNADALQTLIADVTRAVL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea sp. PA05 TaxID=2604466 RepID=A0A5D0QKH9_9ACTN +--DVKKELRALEASFKGRIGAYAIDTATGKTV-GYRSGERFPLLSTFKAPLCAAALHKAR +TEPGLMDKVVKWTADELKPNSPTTEKHVEDGLSVAKLCQAAITESDNTAANMVLKQIGGP +AGLTRYFRSLKDPISRLDRYETELNDWTPKERRDTTTPAAIARDLRLLTTGGALKAKDRE +QLNAWLIANKTGDARIRAGLPKSWKVGDKTGTNGIGGANDIAVVWPSSGAPIILAVYTNR +PVA--STDDAVVAKTATILA--- +>[subseq from] Class A beta-lactamase n=2 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A2S9MG99_9BURK +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMDVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Kibdelosporangium phytohabitans TaxID=860235 RepID=A0A0N9HP83_9PSEU +---YTTDFAALEKRFDARLGVFAVDVTTRRTV-GHREEERFAICSVFKGYAAGALLKANP +LSSGFFRKTIKFGTADLVDGSPVTSTRVQSGMTVAELCHAAITRSDNTAGNQMLKLLGGP +TKLTEFARSIGDPMTRLDRWETALNVVPRGTEQDTTTPSAIAKAYQMLVVGDALGAPERQ +QLKDWLVANTTGGERIRAGLPSGWVTGDKTGTGSFAAANDVAVTWPSPDKPIVIAVLTDK +TAEDAEYDSALLAEATKIAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. S2-17 TaxID=1990687 RepID=A0A2S2C3T0_9NOCA +---LDSRIAELEARHSTRIGVTAVDPTTGAVY-RHRGAERFALCSTFKTYAAAEVLRRTS +EGTSSLDKAVPVEASALVENSPVTAAAVGTSMTLAELAEAALTRSDNTAGNLLLTEIGGP +QAITSLARSIGDDTTRLDRWETELNTALRGDPRDTSTTDGLAEGYRALLLGDELEPTHRR +QLLDWLRASTTSDTRIRAGLPPGWSAADKTGTGRFGTANDAGVVWDREGNPLLLVILTDS +STEAAQPNSDAIAETTTAVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia metallica TaxID=488729 RepID=UPI000D1AE532 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTSFARESGATSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRA +QLTAWMAGGARGTTGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A103ZJQ2_BURCE +--AAQADLTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLPEPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00050FEB44 +--SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDKGAGNLLMDVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPHDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIEWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia caribensis TaxID=75105 RepID=A0A142YWV2_9BURK +---ARERFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM +AERGLLDERVRYGDADLVANSPVTKRRVGEGMTIGELSAAALQHSDNTAANLLLTAVGGP +EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRD +LLKAWMLGNVTGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG +VMKETLPRDEVVVEAARIVFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0004F750D1 +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQAGDKGAGNLLMDVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIEWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Rahnella TaxID=34037 RepID=D7PIH4_9GAMM +-----------------------------SQI-AYRADERFAMCSTSKFMAASAILKESE +VKKNLLTQHVGLKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP +NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWIVGDKTGSGDYGTTNDIAVIWPENKAPLVLVTYFTQ +PEKDAK----------------- +>[subseq from] Beta-lactamase, putative n=1 Tax=Ricinus communis TaxID=3988 RepID=B9TH63_RICCO +---ARERFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM +AERGLLDERVRYGDADLVANSPVTKRRVGEGMTIGELSAAALQHSDNTAANLLLTAVGGP +EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRD +LLKAWMLGNVTGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG +VMKETLPRDEVVVEAARIVFD-- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6H4T4_9BACT +-------------------------------------EERFPMCSTFKFLAAAAVLKRVD +HGKENLERFVRYGAKDILEYAPVTKAHLQDGMTLGALCAAAIEQSDNTAGNLLLDAIGGP +AGLTDFARSLGDQITRLDRKEPELNSAIPGDERDTTTPAAMCSNMQRLLVGELLSESSRH +QLEDWLQHNETGALMMRAAVPKTWSGGDKTGRCANGATSDIAIIRPPGRAPIIIAVYSIG +SKAPADDRAAAIAEVAHAIMK-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudoalteromonas neustonica TaxID=1840331 RepID=A0A558IYL0_9GAMM +-qQVEQEARLIEVTLSGRIGVTVLDTKNGEYW-DYKGDERFPLTSTFKTIACAKLLYDSE +QGDINLNSTVKIKKTDLVTYSPVIEKYVGQAITLDDVCSATMKTSDNTAANIIINAVGGT +ESITDFVRHTGDEKTRLDRFEPDLNEGIPGDLRDTTTPKSIANTLNELLFGSTLSPMSQE +KLKTWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEHQSPIIISIYIAQ +TEVSMKERNEVIAKLGNSIFKVy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFF531F +--RAQSELASLDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Lentzea violacea TaxID=128104 RepID=A0A1G9QPU8_9PSEU +--TVTGKLRQLEKRHNARLGVFATDTGTGRTV-LHRADELFPMCSTFKTIAAAAILRKDR +-DGTLLGKVITYTQAEVDKYGPETGKNLANGMTVSALCEATIIYSDNCAANLLLRELGGP +TAISRFSRSIGDPVTRLDRWEPELNSAEPGRITDTTSPRAIGQSYARLTLGHALNSNDSD +QLTKWLLANTTGGNRIRAGLPSAWRWGDKTGTGSYGTTNDVGIAFPAGRAPIVIAVLSTR +KDPTGGADEPLLARTAELVAATf +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q84EY2_ATLHE +---MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ +KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP +DAVTQFMRGIGDHVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTAPPLTPANRA +TLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ +TEASMKMANEAIAAIGKQLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI00075B1EF1 +----AQAAQVVEQSLQARVGLAVLDTTDGQLW-QYRADERFPMASTSKALICAALLARGP +---GAMKTAWLVKEEAIQSYAPTTENLIGQYVAASQLCAITMRNSDNTAANGVLEMLGGP +EAITSFLRSVGDTVTRLDRNEPSLNEATPGDPRDTTTPQAMVHTLQSLVLGDALKAPDRD +RLIDWLRHNEVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVMWPPGRAPLVVAVYITE +TKASMEERNAAIATIGKAIA--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI000B7A8BDA +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS +LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARTSGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGDTLQEPQRA +RLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI000DD4B65A +--ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KDKSVLTHSVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ +SSASMDERNKAIATIGKQVFTYf +>[subseq from] Beta-lactamase n=2 Tax=Terribacillus aidingensis TaxID=586416 RepID=A0A285N7P6_9BACI +-----DAFSQLEETYDARLGIFAIDTGSGETI-AYREDERFGFASTHKALSVGVLLLQNS +--VENLNKKISITSDDLVNYNPITEKNVNTQMTLKELSEASISYSDNAAANLIFAEIGGP +EGFEQGLRAVGDQVTDSSRIEPELNHVEPNQIQDTSTPKAMTESLRAFTLEDHLSSEKRQ +LLIKWLKGNTTGDTLIRAGVPSDWEVGDKSGAGSNGIRNDIAILWPPDKEPIVLSIMSSR +DKAGAEYDDALISKAAEEVI--- +>[subseq from] Class A beta-lactamase n=1 Tax=Amycolatopsis bartoniae TaxID=941986 RepID=A0A557Z878_9PSEU +-------FADLEARFGAHLGVYALDTGSGRDV-AYHADQRFAYASTIKALATGAVLRKES +----DVDKMLTYSPAEVVSHSPVTGDR--TSVTLREAARAALQQSDNTAGNLLFRELGGP +QGLDAALHEVGDTTTHADRTEVTLNEAVPGDVRDTSTPRAMATSLRTFLLGDALPADARA +LLADWMRGNTTGATLIRAGLPAQWTVADKSGAGNYGTRNDIAVAWPPSGAPVVLAVMSTK +DAKDAAYDDGLVARAASVAL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides franklinii TaxID=948102 RepID=A0A1S1L517_9MYCO +---KSTELAALENDFGGRLGVHALDTGSGDTL-SHRANERFIMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYRQADVMEWAPIASQHVGEGMTIAELCDATIRYSDNTGANLLIAELGGP +KETEKYVRSLGDNVSRMDRLEEDLN--IPDGDLDTSTPLQLATNLRRLALDEGLDAQGRD +LLTDWLKRNTTGDQSVRAGVPAGWTVGDKTGGGFKGETNDIAVIWPPGRAPIVVAVLAIP +DDPKSTKGKPTIAAATRIALKAf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces albus (strain ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 / NBRC 107858) TaxID=1081613 RepID=A0A0B5F4A0_STRA4 +---LSRELRALEGRFGARLGVFARNAVTGASV-RYRAGETFPICSTFKTLATAAVLRDLD +QNGEFLAKTIRYTAQEVEDYGPITGENLAHGMSVEALCAAAVSYSDNAAANLLLRELGGP +RAVTRFCRSLGDPITRLDRWEPELNSAEPWRTTDLTTPAEVGLDYGRLVLGKALPRGDRE +LLTGWLRGNTTGDARLRAGLPEDWTVADKTGTGEYGTTNDVGIAWTGDGTPLILSVLATQ +PDPEAPAVDALIAETARLLV--- +>[subseq from] class A beta-lactamase n=2 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI001261FFA5 +--ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD +AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP +AVLTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ +QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQDPMFVSIYLTQ +TEATFDERNAAIVTIGKSIFDTf +>[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea sp. FMUSA5-5 TaxID=2720023 RepID=UPI0014390D7C +--QVTKELRALEASFKGRIGAYAIDTATGKTV-GYRPGERFPLLSTFKAPLCAAALHRAR +TEPGLMEKVVKWTADDLKPNSPTTEKHVEDGLSVAKLCEATITESDNTAANMVLKQIGGP +AGLTTYFRSIKDPISRLDRYETELNDWTPKEKRDTTTPAAIARDLRALTTGDALNAKDRE +QLNAWLIANKTGDARIRAGLPKTWKIGDKTGTNGIGGANDIAVAWPNSGAPIILAVYTHR +TV--AATDDSVVAKTATILA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QC20_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTGPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAVWVVTAYLQG +ASVDYDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. E7m48 TaxID=1561197 RepID=UPI0006D3B116 +---ARERFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM +AERGLLDERVRYGDADLVANSPVTKRRVGEGMTIGELSAAALQHSDNTAANLLLTAVGGP +EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE +LLKAWMLGNVTGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG +VMKETLPRDEVVVEAARIVFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI0007EBE46D +---IDDQLAELERRDNVLIGLYAANLQSGRRI-TRRPDEMFAMCSTFKGYAAARVLQMAE +HGEISLENRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGEALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS +QAHDAENLRPLIGELTALV---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0004F8C26A +---AQAELAALEKASNGRLGVAALDSSSGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRVLYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQAGDKGAGNLVMGVLGGP +QAVTSFAHESGDTTFRLDRWEPELNRAAPGDERDTSTPLAMVDTLQRLLLGDTLREPQRA +QLTEWMTGGARGATGIAAAVPPGWRIADKAGSGGHGTTTDVAVLWPPSRAPIVLAVSFTQ +PAADAAARADVVASAARIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / NRRL B-24157 / PYR-1) TaxID=350058 RepID=A1T7L6_MYCVP +---LDQRIEALGQRHNAQIGLYALDLDTQRGI-EFGADEPFAMCSTFKAYAAAAVLQRTQ +TGELTLNDAIPIEPGDIRPHSPVTEPRVGTSMSLAELCQAALQQSDNAAANGLLRVLGGP +QAITAFARSIGDHRTRLDRWEVELNSALPGDPRDTSTPRALGDGYRNILTGDVLNPPTRR +QLLDWMLANQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVAYGPAGQQVLLSLMTRS +AIPDAPSLRPLIGELAALAL--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. YC-RL4 TaxID=1682113 RepID=A0A172UNT5_9MYCO +---VTLDLAAVEDRYRARIGMFAVDLNSAARL-QHRPDDRFAMCSTFKTYAAARVLQLTA +HGQLRLDTPVLVQASDIVENSPVTSANVGGSMTVEQICAAALEKSDNTAGNLLLQRIGGP +PAITTFARSVGDDQSRLDRWETELNTALPGDPRDTTTPRALASGYREVLVGDALTHELRE +RLLSWMTANATSQKRFRAGLPAGWTSADKTGAGDFGSTNDAGLLIGPAGQRIVMVVLTRS +RDYDTPPLNEAIADTVRLTVDRf +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium insubricum TaxID=444597 RepID=A0A1X0DEG1_9MYCO +--RATAELGALERRFGGKLGLFALDTANGSTV-SHRGDERFLMCSTVKTFIAATVLHRRL +TEAGLLDRTIHYTPADILEWAPVTATHLYDGMTVAQLCEAMITQSDNTAANLLIATLGGP +AVTQEFVRTLGDNISRMDRNETALN--YPDGDKDTSTPAQLVSTLTRVALDDGLDPHGRE +LLTGWLKANTTGGETIRAGVPARWTVGDKTGSGFAGQANDIAVLWPPDRAPIVIAALTAP +DDRASDQGKPTIAEATRIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces ipomoeae TaxID=103232 RepID=A0A540P4M9_9ACTN +-----------EKEFDARLGVYALDTGTGRSV-GYQADDRFAYASTFKALAVGAILRKYG +--TDGIDKVVRFSRDDVVADSPVSENFVETGMTLRGLCAATLWYSDNTAVNLLLDELGGP +DGLERVLERLGDDVTEMDRYEPDMSDGIPGDIRDTSTPRAMAGSLRAFLLGDALKRNERR +LLRQWMTTNMTGRNLIRAGVPDDWEVADKSGSAGYGGRNNIAVVWPSDGNPIVMAVLSTR +DKQGAERRDALIAKAATVAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A071MEL5_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS +LDASLLPRRILYRRYEVVSGSPITESRVDTGMTIAQLCEAMLQAGDKGAGNLLMGVLGGP +QAVTSFARESGDTTFRLDHWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLHEPQRT +QLTEWMAGGARGATGIAAGVPPGWRVADKAATGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +QRADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=Q9XBX1_SALTM +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KKESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGHSIFDVy +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LF86_STEMA +-----ADFAALEKASGGRLGVTVLYTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTGPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces vitaminophilus TaxID=76728 RepID=A0A0T6LKS3_9ACTN +----ARRLRVLEREHGVRLGAFGWNTTTGRRV-AHRGDELFPMCSVFKTVAVAAVLRDLD +RDGTFLPRVVRYTSRDVERHAPLTGLNLAAGMSVGRLCGAAVSHSDNAAANLLLEQLGGP +AAVTAFCRSVGDDVTRLDRWEPELNSAEPGRVTDTTSPEAIGRTYARLVVGKALDPGDRE +LLAGWLLGNTTGGGRLRAGLPRGWTVAEKTGTGGYGTTHDVGVAWPPGGGPVVMAMLSAT +RDADAAADEPVIARAATVVA--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderiales bacterium PBB3 TaxID=2015565 RepID=A0A257CUU8_9BURK +-------LAALEKKVGGRLGVAILNTASGATV-GHRLDERFGMCSTFKLPLAAAILRKAD +QGTLRLDQWVPYTQADMVSHAPVTQANLHKGMTVGALAEAAQTTSDNPAANLLLGLIGGP +AGFTALMREAGDTITRLDRLEPHMNAVGHADPRDTTTPAAMAANTARMLLGDWLSAGSRA +TLIDWMVATGTGAKRLRAGFPAHWRAGDKTGTGMMDKYNDIAIAWPPGKAPLIVTAYYET +AKKMRDEDQAVLAEVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075E99B5 +----RSELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTVAQLCAAMLQSGDKGAGNLLMNVLGGP +QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA +QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ +AQADAAARADVVASAARIAT--- +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Rahnella TaxID=34037 RepID=D7PII4_9GAMM +-----------------------------SQI-AYRADERFAMCSTSKFMAASAILKESE +VKKNLLTQHVGLKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP +HKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWIVGDKTGSGDYGTTNDIAVIWPENKAPLVLVTYFTQ +PEKDAK----------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces otsuchiensis TaxID=2681388 RepID=UPI0010317947 +---ADTAFGELEQEFDARLGVYALDTGSGAEV-AHRADERFAVASTFKALAAGAVLDQYG +--LDGLNTLTAFDLDDLVSHSPVTERFAGDGMPLGDLAAAAVRQSDNTAANLLLEALGGP +SGFTEALRAVGDDVTRIDRWETELNDVPPGEERDTSTPRALSETLSTYLLGDILDAQEKD +RLAEWMTTNTTSATLIPAGVPDSWIVADKSGGASYGIRNDIAVLWPEEGEPVLLSVLSNR +DEEADESDDALIARAATAALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinokineospora bangkokensis TaxID=1193682 RepID=UPI001300E148 +--TAQRELAALEEVMGGRLGVYAVDTGSGTEV-RHRADERFLMCSTAKVLVSSAVLQARS +GQPGLLDRVIRYTPADLLAHSPTTAQHVSEGMTVAALCEAALTVSDNPAYNLLLPLVGEP +EGLTAYLRTLGDTTSRCDRTEPTLNDTTPGDTRDTSTPAAYAATLRKLTVENALSAENRT +QLLTWMRASTTGKDLIRAGLPPTWDVADKSGSGSQGEVNNAATIQPPGRAPWVIVLFTAP +TKP-GATTRPTLAEATRTIAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Poseidonocella sp. HB161398 TaxID=2320855 RepID=UPI001107FCEB +---LGATLASLEERLGARAGVVLVDTATGRRW-GYRAQERFAMNSTVKVPVCGAILERAE +HGSLALDDVLPVPEEEILDYAPVTEKAAGGGMAIGDLCLAALDMSDNTAANLLIDRLGGP +QAVSAFLRALGDPVSRLDRREPALNDVPPGELQDTTTPAAMAASLQALFLGDALSPASRA +QLAGWMSHGGVTGALVRAEAPAGWQIADKSGAGAQ-TRNLVALVTPPGRDPWVLAMYLEA +PGRDFATRNAALREIGAAAL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. IDO3 TaxID=1705310 RepID=A0A2A4CG27_9BURK +--AAQADLATLEKASNGRLGVAVLDTSNGTRI-AYHARERFPLCGTYAVSAAAAILARGA +LDASLLPRRILYRRYDVVAGSPVTESHVDTGMTIAQLCVAMLQSGDKGAGNLLMNVLGGP +QSVTAFAHESGDTTFRLDRWEPELNEAAPHDVRDTSTPVAMVDMMKRLLLGDTLGEPQRA +QLTEWLAGGARGATGIAAGVPSGWRIADKAGSGGYGTTTDVAVVWPPSRAPIVMAISFTQ +PRADAAARADVVASAARIAS--- +>[subseq from] Beta-lactamase n=1 Tax=Atlantibacter hermannii TaxID=565 RepID=Q93D81_ATLHE +---MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ +KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP +DAVTQFMRGIGDHVTRVDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTAPPLTPANRA +VLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ +TEASMKMANETIAEIGKQLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. ENV425 TaxID=2042960 RepID=UPI000C9CDACA +--RLDAVLADLEERRRVRLGVLAHDPGRGLTY-ARRADDRFAMCSTFKVYAAAAILRLES +QGSLRLDDTVPVDPADIVENSPVTSEAQGRTLTLAQLCDAALTRSDNTAGNLLLRRLGGP +TAVTAFARSLGDTATTLDRWEPELNSAEPGDVRDTSTASGLARGYRELLLGSGLPAAGQQ +TLMGWMRASVTSGQRIRAGLPAGWTAADKSGAGRYGTVNDAGVLWSPDGSPLVLVLLSDS +VTPDAAHDNAAIAEATAVIVE-- +>[subseq from] Beta-lactamase OXY-1 n=2 Tax=Legionella jamestowniensis TaxID=455 RepID=A0A0W0ULU2_9GAMM +--PLQEKLAELEVSAGGKIGVSAVNTANNQHL-QYRAMERFPMGCTSKVVGVAAILKKSM +SDPTLLQHKMHYKKEDLAAWSPITEKHVADGMTVSELCAAAITVSDNTAMNLLVKKLGGL +QAINAYARSIGDKYFRVDNWPKEAFSGGEGNLYDSSTPAAMEKSLTKLTLGDALARSQRE +QLLKWLKDNTTGETRIRAGVPKNWMVGDKTGTGSYGTTNDIAIIWPPGCAPLVVTIYFTK +DKKDAVKQDEVVASATRLLLDEf +>[subseq from] class A beta-lactamase n=1 Tax=Marinobacter bohaiensis TaxID=2201898 RepID=UPI000DAEA2B0 +--RLSDTVEKVENQLDARVGLSLVDTGSDFSW-SHRADERFLMNSTIKVLICGAVLARVD +EGAMSLADPLPVRQDDILSYAPVTKEQVGQDMTLGELCYAALDMSDNTAANLLLEHLGGP +ASVTRFLRRIGDSVSRSDRYEPALNTGAPGDPQDTTRPVAMSDTLSKLLLGEALTADSRD +QLVAWMSHGGVTGALLRDDAPASWHIADKSGSGDT-TRNIVALITPDDGAPRIVTLYISD +ADADFKTRNAALKELGAAVI--- +>[subseq from] Beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A4P8JHB0_ALCFA +----AQAAQVVEQSLQARVGLAVLDTTDGQLW-QYRADERFPMASTSKALICAALLARGP +---GAMKTAWLVKEEAIQSYAPTTENLIGQYVPASQLCAITMRNSDNTAANGVLEMLGGP +EAITSFLRSVGDTVTRLDRNEPSLNEATPGDPRDTTTPQAMVHTLQNLVLGDALKAPDRD +RLIDWLRHNEVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVMWPPGRAPLVAAVYITE +TKASMEERNAAIATIGKAIA--- +>[subseq from] Beta-lactamase n=2 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A0D1GG05_VIBPH +--KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD +TDLSLQARDQLIAHI-------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KIT9_9BACT +-----SLFQELEEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS +--IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFTLLDGP +NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQWAFNLKEYVTGDILSDDKKE +IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRNDIAIVTPPNKKPIFVAVLSKK +AEQDAEYDNKLIADATKIIFD-- +>[subseq from] Beta-lactamase n=1 Tax=Lysobacter enzymogenes TaxID=69 RepID=A0A1H2RD47_LYSEN +--ALGERLAKLEQRSGGRLGVAVLDTADGRHW-ATRGDERFAMCSTYKLPLVAAVLRKAE +LGEIDLYARIAVPQAALVPYSPATAPIARAGASVAQLCEASMTISDNTAANLLLPLVGDP +AGVNRFLHGIGDDISRMQRMPGAPLRA--GDANDTTTPNAMLATMRRLLLGDALNPASRQ +RLTEWMLASKTGDTRLRAGLPQRWRVGHKTGTGQ-GTANDIAIVWPGRRKPVLIASYLTD +AWGDDELRNSVLADVARTLAAHw +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf88 TaxID=1736244 RepID=UPI0006FE08D7 +----GAALARIAGDLGGRAGIAVLDTGGGPAL-LHDAEGAFPLCSTFKLLLAAAILARVE +AGRERLDRRHAYGEADLDTYAPVTTRALRAGMSVEALCAAALVWSDNTAANLLLAALGGP +AALTAYGRDLGDPVTRLDRTEPDLNAAVPGDPRDTTRPAAMAATVGKILLGPSLTEASRA +RLEGWMTASRTGTKRLRAGLPGDWGVGDKTGSGAYGTANVVALLRPPARAPLVAAIYLTG +SDTTSEARDAAHAAIGRVIAATy +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. L-1-4w-11 TaxID=2572576 RepID=A0A4U1L365_9SPHN +---ADGALEALRRRADVRLGLAVHDTGTGRRL-TIDGMGRYAMCSTFKAPLAAAVLARVD +AGRLRLDQPVRFGDGDLLDYAPAVRARRAEGMTVAELCEAAVVLSDNSAANLLLPLIGGP +AGLTRWFRSMGDGVSRLDRTEPTFNDVRGDETRDTTSSLAMAATLERMLVGDVLSSASRA +RRIEWMVASRTGASRLRAGLPADWRAGDKTGTSGDGWFNDIAIIWPPQRKPIVVACYLDA +PGADTAVADAVHADIGAQI---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000DC5ECE3 +--AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTENHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPEPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00049FFE88 +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +ARRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR +QFADWLIDNQTGDACLRAGLGKRWWVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG +ASVDDDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium pulveris TaxID=36813 RepID=UPI00138BAD9E +---IEAQIAALERRHNAVIGVYASNLDSPRTV-AHRAQERFAMCSTFKTYAAARVLQMAD +RGELSLEQSLFVDPKDILINSPITEARAGGELTLAELCQAALQRSDNTAANMLLATLGGP +QAITTFARSIGDAESRLDRWETALNSAIPGDPRDTSTPRALGNGYRNLLAGDALAPPQRS +LLEDWMRANQT--SSMRTGLPDGWTNADKTGSGDYGSTNDVGIAYGPENQRVLFALMTRS +QTSDAQGLRPLIGELTSVV---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces vitaminophilus TaxID=76728 RepID=UPI0003A1EBA4 +----ARRLRVLEREHGVRLGAFGWNTTTGRRV-AHRGDELFPMCSVFKTVAVAAVLRDLD +RDGTFLPRVVRYTSRDVERHAPLTGLNLAAGMSVGRLCGAAVSHSDNAAANLLLEQLGGP +AAVTAFCRSVGDDVTRLDRWEPELNSAEPGRVTDTTSPEAIGRTYARLVVGKALDPGDRE +LLAGWLLGNTTGGGRLRAGLPRGWTVAEKTGTGGYGTTHDVGVAWPPGGGPVVMAMLSAT +RDADAAADEPVIARAATVVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D005F2B +--SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia latens TaxID=488446 RepID=A0A1B4P1I8_9BURK +---AQAELAALEKASNGRLGVAALDTSSGTRI-AHHARERFPLCGAYAVVAAAAILARGS +LDASLLPRRVLYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQAGDKGAGNLVMGVLGGP +QAVTSFAHESGDTTFRLDRWEPELNRAAPGDERDTSTPLAMVDTLQRLLLGDTLREPQRA +QLTEWMTGGARGATGIAAAVPPGWRIADKAGSGGHGTTTDVAVLWPPSRAPIVLAVSFTQ +PAADAAARADVVASAARIVT--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBA8_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAEKDLLSYAPVARRHVGKGLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG +ASVD------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007566842 +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA +LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLSEAMLQFGDKSAANLVMSVLGGP +QTVTEFARASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPGRA +QLTKWLLGSANGVAGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADAAPRADVIAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000752005B +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA +LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLSEAMLQFGDKSAANLVMSVLGGP +QTVTEFARASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPGRA +QLTKWLLGSANGVAGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADAAPRADVIAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter persici TaxID=1076596 RepID=A0A1U9LHH7_9PROT +------VIAVYEKATGGRIGMYACNLATRQRL-TWRENERFALCSTFKVSLVALVLQRVE +QGKDRLDEAVSYTKADIERYAPVAQASLEAGMSVRALCQAAIEQSDNACTNLLLARVGGP +ENLTRFWRSLGDQTTRLDDWEPDLNRVPPGSVRNTTTPAVMAGVLEHLLFGEVLSASSRL +LLTEWLKGCQTGRNRLRAGFPAGWEVGDKTGTNGQDAAGDCAVAWPSPRTPLIVCVYTRG +GHPAEDQFRAAFAGIARLA---- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium moriokaense TaxID=39691 RepID=A0A1X0HIQ4_9MYCO +--SVDASIEDLEQRNNAAIGVFAANLASGKTV-AHRAQDPFAMCSTFKAYASARVLQMAQ +HGELSLDDTMFVDPAGILPNSPVTQPRAGGDMTLAELCQAALQQSDNAAANLVLTRIGGP +QAITAFARSIGDESTRLDRWEIELNTAIPGDLRDTSTPEALGGGFRALLTGDVLASPQRR +LLEDWMRANQT--SSMRAGLPPGWTTADKTGSGDYGSTNDVGIAYGPDGERVLLAFMTRS +KADDAENMRPLIGELAALV---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. UNC363MFTsu5.1 TaxID=1449069 RepID=UPI00048021B8 +-qSLDSTLDALEARYSTRIGVTAIDPASGRTY-RHRGEERFALCSTFKTYAAAEVLRRTV +TGASSLEEPVMVDPGDVVENSPATEAAAGTTMTLRQLAEAALTRSDNTAGNYLLEEIGGP +PAVTALARDIGDESTRLDRWEPELNTALRGDPRDTSTPDGLAQGYRALIVGDALGSAERA +QLGDWMRASKTSDKRIRAELRPGWTAATKSGAGSFGTVNDAGVVWDPDGNPLVLAILTDS +LTADAQGNNQAVADTAAAVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Roseibium sp. TrichSKD4 TaxID=744980 RepID=E2CMP1_9RHOB +-----EQFQAFEHELGGRLGVAIWDLETGSKT-GWRADERFAMNSTFKFMLVAATLKRIE +NGDEQFDRSIDIDEADLVPWTPVTEKHIGQTMTIHELCSAVMTKSDNLATNYLLKAMGGP +AKLTALLRDAGDDVSISSRYEPEANAVGQNDDRDTSTPNAMVSNLERFVLGSTLSKASRA +QLFDWMVENTTGLKRIRGGLPDDWNAGDRTGTGSGGRASNIAIAYPPGRAPVLFAVYTDG +SHRYPRDISKVHAEIGRLVSE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A212NCV8_KLEPN +-----------------------MDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKA---------- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A1D7ZKC3_9BURK +--TAQAELAALEKASNGRLGVAALDTSSGVRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHDSGDPTFRLDHWEPELNKATPGDERDTSTPVAMVDTLQRLLLGDTLREPQRT +QLTEWLTGGARSAAGIAAGVPSGWRIAGKAGAGGYGTTTDIAVVWPPSRAPIVMAVSFTQ +PQADAAARADVVASAARIVTGAf +>[subseq from] Beta-lactamase n=2 Tax=Pseudomonas sp. 43NM1 TaxID=1904755 RepID=A0A2N1DX43_9PSED +--DIEIQLQKLEREHGGRLGVALMNCSTGAIA-SHRGNERFLFNSTSKLFIAAAVLARVD +SGEETFDHRLVVSESDLGGWTPITEKQLGEPITVAELCQAAVAWSDNAAANVLIRSVGGP +EAVTAYLRSISDDTTRLDRYEPDLNEDHEGDERDTTTPLAMMKTLQLLLLGEVLLPSSRH +QLAAWMIEGKTGGARLRAGMPASWLVGEKTGTNGVGNANDIGVAWPADRGAVIAIAYTFM +PNASKEQRDKAIALIGKLA---- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. AU17325 TaxID=2015348 RepID=A0A228IBF1_9BURK +--AAQAELTALEKASNGRLGVAALDTSSGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLHEPQRT +QLTEWMAGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Actinokineospora spheciospongiae TaxID=909613 RepID=W7J1S7_9PSEU +----AEELVALESTFGGRLGVYAVDTADGTEV-RHRADERFLMCSTAKVPVSAAVLRRRL +AEPGLLERVIHYTEADLLEYAPVTSEHVAEGMAVADLCVAALTRSDNTAVNLLLPLVGGP +AGVTDFVGTLGDRTTRFDRPEPDLNVTAPGDERDTSTPLALSSTVRALVVGDGLDRPGRE +LLAGWMRASVTGKDLIRAGVPAGWDVADKSGSGAQGEVNNVAVVWPPNRAPWVITVFTSP +TDPKTTRGRTTVAAAAGIIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000751E84C +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D00746D +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI0012AD538D +--ALVDIIKQQEKALNGSIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KDKSVLTHPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHDPMVVSIYIQQ +SSASMDERNKAIATIGKQVFTYf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0007530A87 +----RSELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP +QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA +QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ +AQADAAARADVVASAARIAT--- +>[subseq from] Class A beta-lactamase n=2 Tax=Streptosporangiales TaxID=85012 RepID=A0A1U9ZR50_9ACTN +--QVTKELRALEASFKGRIGAYAIDTATGKTV-GYRSGERFPLLSTFKAPLCAAALHRAR +TEPGLMEKVVKWTADDLKPNSPTTEKHVEDGLSVAKLCEATITESDNTAANMVLKQIGGP +AGLTKYFRSLKDPVSRLDRYETELNDWTPKEKRDTTTPAAIARDLRALTTGGALNAKDRE +QLNAWLIANKTGDARIRAGLPKTWKIGDKTGTNGIGGANDIAVAWPNGTAPIILAVYTHR +TV--AATDDSVVAKTATILA--- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. 37zxx TaxID=1550073 RepID=UPI00053BFC2E +----RNPFEAIRAETGGRLGLAVHDSGTGRRL-SLDADSRFAMCSTFKAPLAAAILARAD +AGRLDLAQMIRFGEGDLVGHSPTTSANVAAGLSIEALCEAAVTVSDNGAANLLLPQLGGP +AGLTRFFREQRDTVTRLDRDEPSLNLVRGGDVRDTTTPQAMAALLEHLFTANTLSPASRD +KLLGWMRVSTTGLARLRAGLPKSWQVGDKTGTSGEGYVNDIAIATPPGRKPIFIACYLDA +PGLAPAKAEEAHARIGSLIGDLf +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI0012AEA490 +-sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRAIGDKATRLDRIEPRLNEATPGDSRDTTTPNAILNTLRTLVEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLVAQISQLILQKy +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium gastri TaxID=1777 RepID=A0A1X1UW73_MYCGS +--NVQGRFAELEHRYAARLGVYVPASGPTAAI-AYRADERFAFCSTFKGLLVAAVLHQYP +--LSHLDKVVTYTSADIRSTSPITQLHVATGMSVGELCDAAIRYSDGTAANLLLADIGGT +TAFTGYLRSLGDSVSRLDQEEPELNRDPPGDERDTTTAHAIALDYQQLVLGDALPADKRA +MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPSGIPHVVAILSDR +AGYDAEPSEALVADAARCVAQ-- +>[subseq from] Class A beta-lactamase n=2 Tax=Burkholderia TaxID=32008 RepID=A0A2S5E7H8_9BURK +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS +LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARTSGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRA +RLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Lechevalieria fradiae TaxID=200378 RepID=A0A1G7P8M4_9PSEU +----HDALTELEKKFDARLGVFAA--GGDRTV-EHRADERFAFCSTFKGLAAAAVLHHHP +--MTHLDTVVTYTEADLMKSSAITRQHVRTGMTLRDLCDAAVRHSDGTAGNLLLREAGGP +AELTAYLRGLGDTVTRMDRIEPDITSAVPGDPRDTATPRSLGTDYRRLVLGDALPPEKRA +FLTDLLERSVTGAKRVRAGAPAGSRVAGKTGTGGYGTVNDIAVVWPPGREPVLVAVMSSR +AAADAGYDEALVAEAAAYVLK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Achromobacter sp. TaxID=134375 RepID=A0A5N7ZRW2_9BURK +--TLSRELVRLETASRGRLGVALLDTASGQAA-GHRGDERFLMLSSFKTLAAAYILARAD +RGEDQLTRRIPITEADLQEHAPVTRLHVGPQMTLAELCEATITTSDNTAANLMHRSYGGP +QALTRYIRSLGDTVTRHDRYEPELNRPHAGAPLDSTSPNAMNGTLNALLFGAALKPASQQ +LLRSWLLANTTGGKRLRAGFPPDWKVGEKTGTYSKVGANDAGYAQAPGGAPILVCAYLET +TAVPMPERDGIIAEVGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075FDDBB +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCMAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella sp. 381-Salad TaxID=678983 RepID=D7PIK5_9GAMM +-----------------------------SQI-AYRADERFAMCSTSKFMAASAILKESE +VKKNLLTQHVGLKKSDLVNYNPITEKHLKEGMTIGELAAAALQYSDNTAMNKLIEHLGGP +HKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWIVGDKTGSGDYGTTNDIAVIWPENKAPLVLVTYFTQ +PEKDAK----------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Achromobacter denitrificans TaxID=32002 RepID=A0A3R9G643_ACHDE +--TLSRELVRLETASRGRLGVALLDTASGQAA-GHRGDERFLMLSSFKTLAAAYILARAD +RGEDQLTRRIPITEADLQEHAPVTRLHVGPQMTLAELCEATITTSDNTAANLMHRSYGGP +QALTRYIRSLGDTVTRHDRYEPELNRPHAGAPLDSTSPNAMNGTLNALLFGAALKPASQQ +LLRSWLLANTTGGKRLRAGFPPDWKVGEKTGTYSKVGANDAGYAQAPGGAPILVCAYLET +TAVPMPERDGIIAEVGRLAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides immunogenum TaxID=83262 RepID=A0A0N1LXF3_9MYCO +---KSTELASLEQDFGGRLGVHALDTGSGDTL-SHRANERFIMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYTQADLQEWAPIASQHVGEGMTISELCDATIRYSDNTGANLLIAELGGP +KETEKYVRSLGDNVSRMDRLEEQLN--IPDGDLDTSTPSQLVTNLRRLVLDEGLDGPGRE +LLTDWLKRNTTGDQSVRAGVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVVAVLAIP +DDPKSTKGKPTIAAATRIVLKAf +>[subseq from] Beta-lactamase class C n=1 Tax=Burkholderia sp. JKS000303 TaxID=1938747 RepID=A0A2A9M2B8_9BURK +--AAQADLATLEKTSNGRLGVAVLDTSDGTRI-AYHARERFPLCGTYAVSAAAAILARGA +LDASLLPRRILYRRYDVVTGSPVTESHVDTGMTIAQLCVAMLQSGDKGAGNLLMNVLGGP +QAVTAFAHESGDTTFRLDRWEPELNDAAPHDVRDTSTPVAMVDMMKRLLLGDTLGEPQRA +QLTAWLAGGARGATGIAAGVPPGWRIADKAGSGGYGTTTDVAVVWPPSRAPIVMAISFTQ +PRADAPARADVVASAARIAS--- +>[subseq from] Beta-lactamase n=3 Tax=Vibrio TaxID=662 RepID=A0A0P7F1J4_VIBAL +-sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNAILNTLRTLVEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLVAQISQLILQKy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007541AB3 +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNRAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI00063DADAF +-sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNAILNTLRTLVEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLVAQISQLILQKy +>[subseq from] class A beta-lactamase n=1 Tax=Lechevalieria fradiae TaxID=200378 RepID=UPI000B7E5B85 +----HDALTELEKKFDARLGVFAA--GGDRTV-EHRADERFAFCSTFKGLAAAAVLHHHP +--MTHLDTVVTYTEADLMKSSAITRQHVRTGMTLRDLCDAAVRHSDGTAGNLLLREAGGP +AELTAYLRGLGDTVTRMDRIEPDITSAVPGDPRDTATPRSLGTDYRRLVLGDALPPEKRA +FLTDLLERSVTGAKRVRAGAPAGSRVAGKTGTGGYGTVNDIAVVWPPGREPVLVAVMSSR +AAADAGYDEALVAEAAAYVLK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides franklinii TaxID=948102 RepID=A0A4R5P9F8_9MYCO +---KSTELASLEKDFGGRLGVHALDTGSGDTL-SHRTNERFIMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYTQADIMEWAPIASQHVGEGMTIAELCDATIRYSDNTGANLLIAELGGP +KETEKYVRSLGDNVSRMDRLEEDLN--IPDGDLDTSTPLQLATNLRRLALDEGLDAQGRD +LLTDWLKRNTTGDQSVRAGVPAGWTVGDKTGGGFKGETNDIAVIWPPGRAPIVVAVLAIP +DDPKSTKGKPTIAAATRIALKAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075F459C +----RSELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP +QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA +QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ +AQADAAARADVVASAARIAT--- +>[subseq from] UPI001444F354 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI001444F354 +---LSRELRALEGRFGARLGVFARNAVTGASV-RYRAGETFPICSAFKTLATAAVLRDLD +QNGEFLAKTIRYTAQEVEDYGPITGENLAHGMSVEALCAAAVSYSDNAAANLLLRELGGP +RAVTRFCRSLGDPVTRLDRWEPELNSAEPWRTTDLTTPAEVGLDYGRLVLGKALPRGDRE +LLTGWLRGNTTGDARLRAGLPEDWTVADKTGTGEYGTTNDVGIAWTGDGTPLILSVLATQ +PDPEAPAVDALIAETARLLV--- +>[subseq from] class A beta-lactamase n=2 Tax=unclassified Rhodopseudomonas TaxID=2638247 RepID=UPI0013E0080A +--EIEGRLRDLERSSGGRLGVAILDSKDGRLV-GHRLDERFALCSTFKALAVAFVLARVD +RGEESLDRRIAFTERDLVSPFTATKPHVGAEMTVAALCEAAITVSDSTAANLLLDSFGGP +SALTAYLRSLGDPVTRVDHRELELNIVRPGEIHDTTSPRAMVGTLQRLLLGSALSASSRA +RLTTWMIEARDAARRLRVGLPNGWRIANKPGTWAKISTNDIGVIWPPGRDPIIVAAYLGE +APGSIKDQEAVLAQVARIIAE-- +>[subseq from] Uncharacterized protein n=1 Tax=Aeromicrobium sp. PE09-221 TaxID=1898043 RepID=A0A200HHB7_9ACTN +-------LSAEAAEAGVDLSATVTDLGSGETF-QIGGQEPVKAASIIKLPLLAALMDEAD +RGRLSLDEVVTIEASNIVGGSGTLRDREPLDISIAELMELMVQVSDNTATNVLIDRAGGF +DGVNEYIEGLGFEHLWLGRKMI--HPASPPLQENWITSGEVNELVRMLYEHEVLSPESSE +HIISLMKGQLV-DTKFGAVIPRE-VLANKTGELAD-VSHDSGLILVPGRE-VALTVTTSF +DPIQRPQVDVYVQRAASIVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Aeromicrobium sp. PE09-221 TaxID=1898043 RepID=A0A200HHB7_9ACTN +----------EARTKGIEIGVAIEDLSEDRQL-FLGAQDRFTTASTIKMSLAAAVMHQVE +RGQLSLDDVVTITEDERYGGSGTLKDNPFPQVSVGRMLDLMVTVSDNTATNKLVDVVGGF +EAINTLTQGSGIPQRDLHFGRKMFGPVVPPDGDVWLTPRGMNQLMVLFYDPEFLSAESAQ +HIVELMLAQQV-KTKLGATVPAE-VLAHKTGENDV-VSHDVGMLLVPGQ-EMTLSVFSRG +VEDVQATANPYLQRIGAAVYAY- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces aquilus TaxID=2548456 RepID=A0A3Q9BVG3_9ACTN +---APEGLRELEARHGARLGVFARNIVTGRTV-RYRAGELFPMCSLFKTLASAAVLRDLD +RDGEFLSRRIHYTDADLPKGSDKTREHLADGMTVAELAEVAITFSDNGAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWETELNSAEPWRITDTTSPYAIGRTYGRLVLGDALDGPDRA +LLTHWLRNNTTSGTRLRAGLPPAWTVADKTGGGSYGTNNNVGIAWTEDGTPLLLAVLSTL +PAQDAARDDVLIRDTAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Arthrobacter sp. SLBN-53 TaxID=1570328 RepID=UPI0011523625 +--ALPERIRDLEARHNAFIGVFGMNLDSGMSV-RHRAGESFAMCSTFKAYAAAAVLRRVA +DGELSLEKPVFVDPAGILPNSPVTEERAGGQMTLAELCQAALQRSDNLAANLLLATLGGP +RAITDFARSIGDDTTRLDRWETDLNSAIPGDPRDTSTPEALGMGYRNLLAGDALPPVQRD +LLDGWMRANQT--SSMRAGLPPDWTTADKTGSGDYATTNDVGIAYGPGGTRVLLSIMTRT +QSPDAEGLRPVIGEVAALVL--- +>[subseq from] serine hydrolase n=1 Tax=Aeromicrobium sp. PE09-221 TaxID=1898043 RepID=UPI000B3ECDB1 +-------LSAEAAEAGVDLSATVTDLGSGETF-QIGGQEPVKAASIIKLPLLAALMDEAD +RGRLSLDEVVTIEASNIVGGSGTLRDREPLDISIAELMELMVQVSDNTATNVLIDRAGGF +DGVNEYIEGLGFEHLWLGRKMI--HPASPPLQENWITSGEVNELVRMLYEHEVLSPESSE +HIISLMKGQLV-DTKFGAVIPRE-VLANKTGELAD-VSHDSGLILVPGRE-VALTVTTSF +DPIQRPQVDVYVQRAASIVYD-- +>[subseq from] serine hydrolase n=1 Tax=Aeromicrobium sp. PE09-221 TaxID=1898043 RepID=UPI000B3ECDB1 +----------EARTKGIEIGVAIEDLSEDRQL-FLGAQDRFTTASTIKMSLAAAVMHQVE +RGQLSLDDVVTITEDERYGGSGTLKDNPFPQVSVGRMLDLMVTVSDNTATNKLVDVVGGF +EAINTLTQGSGIPQRDLHFGRKMFGPVVPPDGDVWLTPRGMNQLMVLFYDPEFLSAESAQ +HIVELMLAQQV-KTKLGATVPAE-VLAHKTGENDV-VSHDVGMLLVPGQ-EMTLSVFSRG +VEDVQATANPYLQRIGAAVYAY- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia sienata TaxID=248552 RepID=UPI000A0020AD +--DLSNTLMTLQAKYNVLFGIAAVDTRGRRTF-EWNADDRFAMCSTFKVYAVAAILRLAE +REELDLNDRVPITREDIVMNSPVTFDHIGELMSYYELSRAALVRSDNTAANLLLRRLGGP +RAVTEFARSINDSQTRLDRWEPELNEARAGDPRDTSTASAFAAGYRKLILGDGLSTEYRR +MLTSWMRSSVTSRARLRAGLPLGWVAADKTGSGAYGTANDAGVVWSPNGTSLVLVIFSRS +TTPMAAGADAAVADAAAAVL--- +>[subseq from] Beta-lactamase n=1 Tax=Achromobacter veterisilvae TaxID=2069367 RepID=A0A446CQY1_9BURK +--SLNQALAKLEAASKGRLGVSLLDTASGQAA-DYRGDERFLMLSSFKTLAAAYILARAD +RGEDQLDRRIPIAEADLLEYAPVTRLHVGPQMTLAGLCEATITTSDNTAANLMHRSYGGP +RALTRFIRGLGDTVTRHDRYEPELNRPHAGEPLDTTSPHAMSRTLGILLFGPALQPGSRR +LLQSWLLASTTGGKRLRAGFPADWKVGEKTGTDSQVGANDAGFAQPPGGAPIVVSAYLET +TAIPMAERDRIIAEVGRQAA--- +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=A0A2S2CJ31_9GAMM +--ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLVCAKLLADSD +KDKSVLTYPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ +SSASMDERNKAIATIGKQVFTYf +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI000D07F0E2 +--ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLVCAKLLADSD +KDKSVLTYPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ +SSASMDERNKAIATIGKQVFTYf +>[subseq from] Beta-lactamase n=1 Tax=Arthrobacter sp. SLBN-53 TaxID=1570328 RepID=A0A542P1E6_9MYCO +--ALPERIRDLEARHNAFIGVFGMNLDSGMSV-RHRAGESFAMCSTFKAYAAAAVLRRVA +DGELSLEKPVFVDPAGILPNSPVTEERAGGQMTLAELCQAALQRSDNLAANLLLATLGGP +RAITDFARSIGDDTTRLDRWETDLNSAIPGDPRDTSTPEALGMGYRNLLAGDALPPVQRD +LLDGWMRANQT--SSMRAGLPPDWTTADKTGSGDYATTNDVGIAYGPGGTRVLLSIMTRT +QSPDAEGLRPVIGEVAALVL--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q9JRP6_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR +QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG +ASVDDDQRAAVL-QVGR------ +>[subseq from] class A beta-lactamase n=1 Tax=Oceanicola sp. HL-35 TaxID=1305735 RepID=UPI0004631453 +---LFQTIESIEDRLDARVGLYIRDSGSDWSI-SHRADERFLMTSTFKPMLCAAALRQVD +EGTLNLDAALRIEQGAILDYAPVTQTMVGRTMTIDDLCFAALDMSDNTATNLLIDHIGGP +EAVTRFLRDIGDPVSRLDRREPELNTFAPGDPRDTTTPEAMAATLETMLMGDALTAQSRA +RLIDWMSHGGVTGPLIRASTPADWLIADRSGSGNF-NRNVIAMVTPPDQSPYFISVFLSD +ADADFETRNDAVIGLSQAVMD-- +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=A0A2T3QJQ4_9GAMM +--ALVNIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KDKSVLTYPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ +SSASMDERNKAIATIGKQVFTYf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q2XQU6_PSEAI +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFTTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGHSIFDVy +>[subseq from] Beta-lactamase n=1 Tax=Vibrio chagasii TaxID=170679 RepID=A0A2S7VP23_9VIBR +-----ESIEQIESRVSARIGVAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDAE +HKGLDLDSKVSIKSEDLIVWSPVTKELVGKGISLRDACSATMTMSDNTAANIVLGGIEGP +NGLTQFLRSIGDSHTRLDHLEPELNHARPGDARDTTTPNSIVMTLNELMYGDTLSQASTS +TLTGWMMGNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWNEHRAPLIISVSLTE +TEFTLQQRDKVINEVGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI00021C2EE7 +-----ESIEQIESRVSARIGVAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDAE +HKGLDLDSKVSIKSEDLIVWSPVTKELVGKGISLRDACSATMTMSDNTAANIVLGGIEGP +NGLTQFLRSIGDSHTRLDHLEPELNHARPGDARDTTTPNSIVMTLNELMYGDTLSQASTS +TLTGWMMGNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWNEHRAPLIISVSLTE +TEFTLQQRDKVINEVGQLIFDAy +>[subseq from] Class A beta-lactamase n=1 Tax=Mycobacterium sp. Root265 TaxID=1736504 RepID=A0A0Q8ZWG2_9MYCO +---ADSDFAALEHRHGARIGMWALDLGTGQTL-GYRPDDRQAMCSTFKTYAVGRVLHMVA +GGVLDLNSAIPITAGDIVVDSPVTSKRVGTSMSLAELCEAALVFSDNSAGNALLRSIGGP +PAITSFARGLGDDQTRLDRWEPDLNSALPGDPRDCTTPRALVTGYRALMVGDALDPPSRD +RLLSWMQANVTSDKRFRAGLPPGWTSADKTGAGDFGVTNDAGLLIGPTGQRILVAVLTRS +AEMDAPRLNDAVADTVRLTLAR- +>[subseq from] class A beta-lactamase n=1 Tax=Achromobacter denitrificans TaxID=32002 RepID=UPI000F504684 +--TLSRELVRLETASRGRLGVALLDTASGQAA-GHRGDERFLMLSSFKTLAAAYILARAD +RGEDQLTRRIPITEADLQEHAPVTRLHVGPQMTLAELCEATVTTSDNTAANLMHRSYGGP +QALTRYIRSLGDTVTRHDRYEPELNRPHAGAPLDSTSPNAMNGTLNALLFGAALKPASQQ +LLRSWLLANTTGGKRLRAGFPPDWKVGEKTGTYSKVGANDAGYAQAPGGAPILVCAYLET +TAVPMPERDGIIAEVGRLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Pararhizobium sp. BGMRC6574 TaxID=2590452 RepID=A0A506U760_9RHIZ +-dALSDAVAQVERQLGARVGVTLSDTGSDLAW-SNRSDERFLMNSTVKVAICGAVLARRD +AGKLPLSDTLPVRKADLLSYAPVTKTHVGGRMTIANLCLAALDLSDNTAANILTDRLGGP +QAVTRFFRSIGDGVSRSDRHEPELNTFEPGDPRDTTTPSAMAQTLRKLLLGNALSPASRD +QLAEWMSHGGVTGDLLRADAPKDWRIYDKSGSGDH-NRNIFAVVVPKGRAPWIVTIFISD +TDAGFETRNDALKTIGTAAME-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. LHW50302 TaxID=2250578 RepID=A0A367F4D4_9ACTN +--AAAAAFKKLEAQYGARLGVHAFDTGSGRAV-SYHADERFAYASTHKVFTAAAVLDKYS +-LKGLGDKSLTVGKDVPVGHSPVTSAHVGQQLTLRELCEAAVRQSDNGADNLLVRDLGGP +EKLDAYLEDLGDDVTQMNRYETALTEATPGDKRDTTTPRAFAEDLRAVTLGDALPKPERA +QLDDWLDESPTGTELIRAGVPKEWGVGDKSGAARYGTRNDIAVVRPPGKAPLIVTVMSKR +KKEDADYDDKLVAEAASVVSD-- +>[subseq from] Beta-lactamase n=1 Tax=Thalassotalea sp. PP2-459 TaxID=1742724 RepID=A0A1Q6CH20_9GAMM +-----NQIKKQERLLNADFGVAIFDVEKQSLW-HYNGNSRFPLMSTFKVLACAKLLADVE +KGVQSFDSSTLITKSDLVYWSPVTKHMVGKKMSLKQACSATMTMSDNTAANIILTGIKGP +TALTKFMRDIGDNVTRLDRIEPELNQALKNDKRDTTSPIAMVKSLHTLLFGNILKDPSKA +QLTQWMIDNKVTASLLRSVLPEHWSIADRSGAGGYGSRAIAAVVWSKDQTPLIISIYLTQ +TEATMKERNKAIAAIGESIFTFy +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium chubuense (strain NBB4) TaxID=710421 RepID=I4BHU3_MYCCN +-----ERVEALQRRYNAEIGLYALDLGSGKAL-AFGADEPFAMCSTFKGYASAAVLQRAQ +RGQLALTDTVPITRGDIKPHSPLTEPRVGTAMTLAELCQAALQQSDNAAGNLLLRTLGGP +PAITAFARSIGDDRTRLDRWETELNSAEPGDPRDTSTPHALGEGYRALLAGEVLDAPGRG +QLEEWMRGNQT--SSMRAGLPQGWTTADKTGSGGYGTTNDVGVAYGPGGTRLLLSMLTKS +AGPDAQGLRPMIGELAALVL--- +>[subseq from] LAP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0011108292 +---VTDTIQSTEDHIKGRVGFTEIDFLSGKVLsSHRREERFPMMSTFKVLLCGAILVRVD +KGLEQLERRITYNKHDLDDYSPLTSQHIADGMTVSELCNAAITTSDNTAANLLLSTIGGP +EGLTHFLRSTGDSYTRLDRHEPSLNEAKPGDERDTTTPAAMAQTLQKLLNESVLTEKSRK +KLISWMQEDKVGGPLFRSVLPAGWMIADKTGAGDHGSRGIVALLGPGGKPSRIVVLYITN +TQ--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Pseudohoeflea suaedae TaxID=877384 RepID=A0A4R5PJF3_9RHIZ +-sDLERTVAKVEQQLGARVGLSVVNTDSGITW-FHRKNERFLMNSTFKVPLCGAVLARVD +KGELSLTDTLPVAQSDLVPHAPITERRVGGTMSLAELCRAAIDMSDNTAANLLIDYLGRP +DEVTRFFESIGDSVSRLDAREPELNAFVPGDPENTTSPAAATQTLHALLIGDALSPESRD +VLRGWMSDGGVTGDLLRDYVPAGWQVFDKSGAGSH-TRNLVALVVPQDGTSWIVTIFVSD +VDAPFKTRNDALRQIGKAVVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Ruegeria sp. EL01 TaxID=2107578 RepID=UPI0013C40FDD +--DATARLESAEQRLSARIGVHAENLSTGQVF-QHRPDERFAMCSTFKASLAALCLHRSD +RGQLDLDERLAFQGSDILPTSSVTRGNLSAGMSISDLCQAIVEYSDNTAANLLLKHIGGP +SAITQFFRDIGDTTSRLDRTEMALNSNIAGDERDTTSPQAMARTLSELTMTNLLSDHSRA +LLIQWMRNEQNGQNRIRAAVPGDWAVGNKPGTSPNGVANDIAVLWSPDGTPFVVTVFIDT +QQGRAREAVAAIHDIAGTAL--- +>[subseq from] Beta-lactamase n=2 Tax=Photobacterium damselae TaxID=38293 RepID=A0A2X1XP38_9GAMM +--ALVNIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KDKSVLTYPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ +SSASMDERNKAIATIGKQVFTYf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0012DF73D1 +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKGGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Afipia sp. Root123D2 TaxID=1736436 RepID=A0A0Q6Z2B9_9BRAD +------ALQTYERESGGRIGFHAENLASGAKL-GWRADERFVMCSTFKASLAAFVLARVD +HGEDRLDHMISYGPKDIQPYAPVAKQNLAKGMSMEDMCQAVVELSDNTCANLLLAHVGGP +AKLTEFWRSLGDTVSRLEHYEPELNRTPPGGLDDTTTPVAMAGSLHRLVSGSALSAGSRE +RLTGWMVNCKTGADRLRAGLPKDWKIGDKTGNNGKDGFGDIAVAWPKPDAPIVICAYTRG +GSPTAAQVKTVFTAIGRMAAE-- +>[subseq from] Beta-lactamase n=2 Tax=Corynebacteriales TaxID=85007 RepID=V5XBK5_MYCNE +--ALPERIRDLEARHNAFIGVFGMNLDSGMSV-RYRDGESFAMCSTFKAYAAAAVLRRVA +DGELSLEKPVFVDPAGILPNSPVTEERAGGQMTLAELCQAALQRSDNLAANLLLATLGGP +RAITDFARSIGDDTTRLDRWETDLNSAIPGDPRDTSTPEALGTGYRNLLAGDALPPVQRD +LLDGWMRANQT--SSMRAGLPPDWTTADKTGSGDYATTNDVGIAYGPGGTRVLLSIMTRT +QSPDAEGLRPVIGEVAALVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia transvalensis TaxID=37333 RepID=UPI000A3070AD +--TAEDYFASLERKYDARLGVYAVATATAVAL-THRADDRFAFCSTFKTLAAAAVLHQRP +--LSYLDTVVRYTREDVNSISPITQDHIDTGMSMRDLCDAAIRYSDGTAGNLLMRDIGGP +PQLTAYLRGLGDTVGRMDQYEPELNSDPPGDPRDTTSPRALAAVYQQILLRGALPPDRQA +LLEDWLRRSTTGANTIRAGVPADWTVASKTGHGDYGRANDVAVVRPAGGAPLVIAVMTDR +AAFDAEPPYAMIADVARYVAT-- +>[subseq from] Class A beta-lactamase n=2 Tax=Mycobacteroides franklinii TaxID=948102 RepID=A0A1S1L6B7_9MYCO +----SPHFAALEQEFAGRLGVYALDTGSGTAL-GNRQSERFLMCSTVKVFIVSAILTRRR +TEPGLLEKRIHYTNADILDWAPVTPAHIADGMTVEELCAAAVSHSDNTAANLLIAELGGP +EETEKFVRSIGDSTTNTDRTETDLD--IPDGDKDTSTPEQLVSNLRTLVLGDALDREGRD +KLIGWMKANTTGEQSIRAGVPHGWEVGDKTGSGSRGESNDIAVIWPPNRAPILLAVLTAP +DDPTSTKGKLTIAQATRQAI--- +>[subseq from] Uncharacterized protein n=1 Tax=Actinokineospora bangkokensis TaxID=1193682 RepID=A0A1Q9LQ82_9PSEU +--TAQRELAALEEVMGGRLGVYAVDTGSGTEV-RHRADERFLMCSTAKVLVSSAVLQARS +GQPGLLDRVIRYTPADLLAHSPTTAQHVSEGMTVAALCEAALTVSDNPAYNLLLPLVGEP +EGLTAYLRTLGDTTSRCDRTEPTLNDTTPGDTRDTSTPAAYAATLRKLTVENALSAENRT +QLLTWMRASTTGKDLIRAGLPPTWDVADKSGSGSQGEVNNAATIQPPGRAPWVIVLFTAP +TKP-GATTRPTLAEATRTIAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00057D3B90 +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMDVLGGP +HAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI00102DC618 +-sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNAILNTLRTLVEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLVAQISQLILQKy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=UPI0006261492 +--TVQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS +LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTAFARASGDMSFRLDRWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRT +QLTEWMIGGARGATGIAAGVPLGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVAA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A103HS23_BURVI +----RSELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQAGDKGAGNLLMNVLGGP +QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA +QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ +AQADAAARADVVASAARIAT--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=A0A250L293_9BURK +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS +LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTAFARASGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRT +QLMEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVAA-- +>[subseq from] serine hydrolase n=1 Tax=Georgenia sp. 311 TaxID=2585134 RepID=UPI001111D5D2 +------------AAAGVTLSVAVTGLADGASL-VAGTDERVKAASIIKLPLLATLMADVD +AGHLDLAQVVTIPAGDIVGGSGTLQDRSFPLITVGELMELMVQVSDNTATNVLIDLAGGF +DAVNEYTADLGLEDLRLGRKMI--HPASPPLQENYISAAEVTDLVTLLWDGGILSESSSE +YVLDLMRGQLV-DTKFGAVVP-RAHLANKTGELSD-VSHDSGVILLPGRE-LALTATSSF +TGMPREEADVFVQEAARVVYD-- +>[subseq from] serine hydrolase n=1 Tax=Georgenia sp. 311 TaxID=2585134 RepID=UPI001111D5D2 +---------------GIRASVGFTDLADGGAL-LLGSPAPYNPASVIKLSLLATVMRQAE +RGMLNLDAPVTISPYMVVAGSGSLQHEQMPYTTVRELTRLMVVQSDNTATNVLLYYT-GI +PTTRELLDDLGLEVMRFNRQMFPGDR--ISDPANVLDLADTMGLLEAMYGDDLLAAGSRD +QILTWMGDQEV-DTKFGAVLD-DAPVAHKTGETGN-VTHDVGYFLVPGHE-AAVAVLTEV +TTEAQEIGNPVVQEIGLAIYEY- +>[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI000A1125F1 +--ALSTQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD +AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP +AALTAYLQSIGDNVTRLDRNEPTLNEAAKHDLRDTTTPNAINHTLNTLVLGETLSSTSRQ +QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ +TEATFDERNAAIVTIGKSIFDTf +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. TLI_185 TaxID=2485151 RepID=A0A3N4ZNQ7_9ACTN +---------------------FAHNVRTKQTV-EHRADELFPVCSLFKTLAAAAVLRDLD +RHGEVLARRIHYTEADLVDGSDRTREHLAEGMTVAELADVAIRYSDNTAGNLLLRELGGP +TAITRFARSIGDPVTRLDRWETDLNSAEPWRITDTTTPRAIGRSYARLVLGHVLDRRDRA +LLTHWLLGNTTSGNRFRAGLPKTWTVADKTGGGSYGANNNVGIAWTPDGTPIVLAVQVTK +PDQDAELDNPLIAGTAAFLAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075BEC68 +--AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia asiatica TaxID=209252 RepID=UPI0005C1D23A +----HDRLIELERTFDARLGVYALATGTGATI-AHRADERFAFCSTFKTLAAAAVLHRNP +--LTHLDTVVGYTENDLLKNASITPQHVATGMTIRQLCDAAVRYSDGTAGNLLLREIGGP +AQLTEYARGLGDMVTRMDRIEPAITEATPGDPRDTTSPRAFGTVHQRIVLGDALPADKRA +FLRDLLERNATGAQRIRAGVPRGWTVADKTGTGDYGTLNDIAVVWPPDAAPVVVAIMSSK +ATADAP----------------- +>[subseq from] Beta-lactamase n=1 Tax=Pelomonas puraquae TaxID=431059 RepID=A0A254N762_9BURK +------ALRALERRAGGRLGVAILDTGTGAQT-GLRLDERFALCSVFKLPLAAMILRESD +LGRLPLDQAVPFGKADMLNHAPVTSQHLARGMTVAELAEAAQVTSDNPAANLLLKLIDGP +AGLTTRLREIGDATTRLDRYEPEMNQMPPGDARDTSTPAALAALVQRITLGDVLKPASRA +LLVSWMEKTETGRHRLRAGLPKGWRAGDKTGTFWDEKVNDVAVCWPPGRAPLVVAAFYEA +PKADFEAGQKVLAEVGRIAA--- +>[subseq from] Beta-lactamase enzyme family n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A5P8VF64_BURCE +--AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Nitratireductor sp. TaxID=1872084 RepID=A0A2E0JD53_9RHIZ +--TLSQTVERIESTLGARVGIVIRDTGSDWRW-SHRAEERFLMNSTVKALICGGVLAKAD +AGALALRDALPIRQFDIVSYSPVTQKQVGKAMSIADLCLATLDMSDNAAANLLIGRLGGP +KAVTAFLRDIGDPVSRLDRLEPKLNAFAPGDPRDTTTPAAMIETWHALLLGDVLKPASRT +QLIEWMSHGGVTGALMRASLPKDWAISDKSGAGSH-TRNLVAMVTPPGRAPFLVSIFISD +TDVDFETRNGALKDISAAIVN-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. JS623 TaxID=212767 RepID=L0IW73_9MYCO +--RIQNRIAALERRYDAYVGLFAVDVDDGRAI-SHRGQEAFAMCSTFKGYASARVLQMVE +QGQLTLDQRVFVDPAATVANSPRTAPRAGGDMTLDELCQAALRVSDNTAGNLLLQTIGGP +PAITAFARSIGDPSTRLDRWETELNSAIAGDPRDTSTPEALGGGYRNLLTGDALAPPQRQ +QLEDWMRANET--SSMRSGLPPQWTTADKTGSGAYGSTNDVGIAYGPDGQRVLLALMTRS +QVNDAQNQRALIGELTALL---- +>[subseq from] class A beta-lactamase n=1 Tax=Microlunatus speluncae TaxID=2594267 RepID=UPI0012664828 +---ADAGLAALEKKFDARLGVFAWDTGTGRAI-THRADDRFAFCSTFKGLAAAAVVQGNP +--LSHLETLVRYGEDELMKSSMITKKHVKTGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP +RKLTEFARSLGDEVTRMDRIEPDIVSAEPGDLRDTSSPRALGGDYHQIVLGEALVPDKRA +VLRDLLERNTTGAARIKAVLPKGWKIANKTGTGDYGTINDIAILWPPKSAPLVISIMSSR +PDRNAAYNEDLVAEAAGHVL--- +>[subseq from] Beta-lactamase n=1 Tax=Alcaligenes aquatilis TaxID=323284 RepID=A0A3G2HVU1_9BURK +-----RAVQEVEHSLQARVGLAVLDTADGQWW-QYRADERFPMASTSKALICAALLARGP +---GAMKTAWLIKEEAIQSYAPTTKKLIGQQVSAAQLCAITMRNSDNSAANGVLEILGGP +EAITSFLRGVGDTVTRLDRNEPSLNEATPGDPRDTTTPQAMVQTLRNLVLGDALKAPDRD +RLIDWLTHNNVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVMWPPERAPLVAAVYITE +TKASMEARNAAIATIGKAMA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis alkaliphila TaxID=225762 RepID=UPI000A304C77 +--DLSVEFEALEEEFDARLGVYAVDTGSGEVV-AFREDERFALASTFKALLAGVVLSENS +--LEEMERVVTFDEEVLVPHSPVTEQHLGVGMSLLELCDATVRFSDNAAANLLLDEVGGP +EGFTEALGGTGDEVTNLVRYEVEMAEGVPGDERDTSTAEALVGSLEEFTLGDVLPEDRRE +VLVDLLERNTTGDALIRAGVPEGWVVGDKTGAGGFGTRNDIGVLWPPEGGPIVLAVLSSR +DESGAEHDDALIAQATEVVVE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID10853 TaxID=2706028 RepID=A0A6B2SH77_9ACTN +-----GRLRALEQEYSARIGVFARDTATGATV-QYRARERFPMCSVFKVLAAGAVLRDLD +RHGEYLARRVHYTEELVEKYTPVTGKNIAGGLTVGQLCAAAVSESDNAAGNLLLSRLGGP +TAITRFCRSTGDSTTRLDRWEPELNSAEPWRTTDTTSPGAVGTTVARLVIGRVLTPYHRE +KLTGWLTANTTDGERFGAGLPADWTLADKTGGGDYGVANDVGVVWPPERPPLVLSVLSTK +YDPQGPTDNPLVARAAALVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI000A34379C +--ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KYKSVLTHSVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIVETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTAHEPIVVSIYIQQ +SSASMDERNKAIATIGRQVFTYf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=UPI0008F4DF6C +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS +LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTAFARASGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRT +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Hoeflea olei TaxID=1480615 RepID=A0A1C1YW23_9RHIZ +-aQLEKAVAQVESQLGARVGLAMVDTGTGVTW-FHRKDERFLMNSTFKAPLCGAVLARVD +AGDISLSDVLRIEKADLMHHAPVTEKNVGKDMTIEALCRAAVDMSDNPAANILLHHIGGP +SAMTGYFRSIGDSVSRMDDPEPQLNTFIPGNPRNTTSPAAMAQTLHALLLGDVLSPASRD +LLADWMSHGGVTGNLMRAAAPRSWQILDKSGAGSH-SRNLIAMVTPEGRAPWIVTIFISD +VKAPFETRNAALQSLGRVAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides franklinii TaxID=948102 RepID=UPI0013E89C20 +---KSTELASLENDFGGRLGVHALDTDSGDTL-SHRANERFIMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYTQADIMEWAPIASQHVGEGMTIAELCDATIRYSDNTGANLLIAELGGP +KETEKYVRSLGDNVSRMDRLEENLN--IPDGDLDTSTPLQLATNLRRLALDEGLDAQGRD +LLTDWLKRNTTGDQSVRAGVPAGWTVGDKTGGGFKGETNDIAVIWPPGRAPIVVAVLAIP +DDPKSTKGKPTIAAATRIALKAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075265A5 +--AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVAMIDTLQRLVLGNTLPEPQRA +QLTEWMVGGARGATGIAAGVPPSWRIADKAGTGGYGTTADVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis taiwanensis TaxID=342230 RepID=UPI000693BAA8 +-----AAFEELERTFDARLGVYAVDTATGRNL-AYHADDRFGYASTHKVFTAGAVLQRTP +--IEGLERTVTYGANDLVPNSPITQRNLGTAITLRAAMDAALRYSDNTADNLLFREIGGP +AGMAAALREAGDTTTHADRIEPALNDLAPGEIRDTSTPRALAASLRAFTLGEALPEEKRT +ILTDMMRANVTGDSVIRAGTPAGWQVADKTGTAKYGTRNDIAVVWPPQRAPIVLVILSDR +KAKDSDHDDKLIAQAAAAALGV- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Pseudoalteromonas sp. RA15 TaxID=2518973 RepID=UPI0012318026 +-qQVEQEARLIEVTLSGRIGVTVLDTKNGEYW-DYKGDERFPLTSTFKTIACAKLLYDSE +QGDINLNSTVKIKKTDLVTYSPVIEKYVGQAITLDDVCSATMKTSDNTAANIIINAVGGT +ESITDFVRHTGDEKTRLDRFEPELNEGIPGDLRDTTTPKSIANILNELLFGSTLSPMSQE +KLKAWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEHQSPIIISIYIAQ +TEVSMKERNEVIAKLGNSIFKVy +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea jiangxiensis TaxID=633440 RepID=A0A1G8CJF4_9ACTN +--RARKELRALEASFKGRIGAYAIDTGTGRTI-AYRSGERFPLLSTFKAMACAAVLHKAR +TSEGLMRKVVRWTAAEVQEYSPVTEKHVKDGLTVAQLCKAAITLSDNTAGNMILKQIGGP +AGLTRYFRTLKDPISRLDRWETELNVWTPKEKRDTTTPASIARDLRAVATGDALTAADRR +QLNAWMRATETGDTRIRAGLPKTWTIGDKTGSNSFGGANDIAVVWPKKTAPIIMAVYTNR +AQG-VAGDDSAVARTATILA--- +>[subseq from] Beta-lactamase n=1 Tax=Actinosynnema sp. ALI-1.44 TaxID=1933779 RepID=A0A1V2Q4B0_9PSEU +-----EHLVALERKYDARLGVFALNTSTGASL-AHRADERFAFCSTFKGLAAAAVLHRNP +--MSHLDTLVRYAKQDLLKSGVVTSQHVATGMTIRDLCDAAVRHSDGTAGNLLLRDLGGP +QQLTEYLRGLGDTVTRMDRTEPAIVEATPGDPRDTSTPRSLGTSYQKIVLGDALTEDKRA +FLRDLMERPATGAQRVRAGLPKDWRVADKTGTGDYGTLNDIALVWPPGKAPLLIAIMSSK +AAKDAKYDHQMLAEAASYA---- +>[subseq from] Class A beta-lactamase n=2 Tax=Burkholderia cepacia complex TaxID=87882 RepID=A0A102PIE6_BURCE +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007573686 +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A2X1GKW8_BURCE +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075886CF +--AAQADLTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLPEPQRA +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces olivochromogenes TaxID=1963 RepID=A0A250VRV6_STROL +---------------------------------RHRAAERFPGCSVFKTLAAAAVLRDLD +RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPTTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK +PAQDAAADSPLVAATATVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora sp. NRRL B-11411 TaxID=1463822 RepID=UPI0004C38300 +--RLADSFRQLEREHGARLGVLAHDTGSGATV-RHRADEAFPLCSTFKPLAVAALMRAGD +----DLAARVHYTDADVADHAPVTGR--TRVLTVAELCAAAIEFSDNTAANLLLRRLGGP +TAVTRFCRSLGDPVTRLDRWEPALNSAEPDRTTDTTTPRALARTFARLTLGDALARPDRA +RLTAWLRASTTGTHRLRAGLPPSWTLADKTGTGSYGTANDLALAWPPHRPPLVLAVLSTR +PTPTAAPDEPLLARTAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Terribacillus halophilus TaxID=361279 RepID=UPI000984FEDF +-----DAFSQLEETYDARLGIFAIDTGSGETI-AYREDERFGFASTHKALSVGVLLLQNS +--VENLNKKISITSDDLVNYNPITEKNVNTQMTLKELSEASISYSDNAAANLIFAEIGGP +KGFEQGLRAVGDQVTDSSRIEPELNHVKPNQIQDTSTPKAMTESLRAFTLEDHLSSEKRQ +LLIKWLKGNTTGDTLIRAGVPADWEVGDKSGAGSNGIRNDIAILWPPDKEPIVLSIMSSR +DKAGEEYDDSLISKATEEVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFE50CC +--SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIEWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. I6 TaxID=2483113 RepID=A0A3N0DBG1_9ACTN +----VREFTELEDRFEARLGVYAVDTGTGREV-VHNDEESFAYASTFKALAAGAVLREYS +--LSGLDRVIRYSADEMVAHSPVTAKHVGTGMSLAELCDAAVRLGDNTAANLLLDQMGGP +RGLDAALEEIGDDVTRMERRETQLNEWSPGSLSDTSTPRALAGALRAYALEDALGKGERA +QLTAWLRASATGAELIKAGVPKDWLVGHRAGAGGYGVRNDIAVVWPPDSAPIVMAIMSNG +LRRDADYDDRLIAGAASVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Prauserella rugosa TaxID=43354 RepID=UPI0011A64EAA +--DVAGELAAVEQRFGGRLGVYAVDTGSGALV-QHRQRERFLMASTAKLPIVAATLGRGV +----PLDRSVPVRQEDVLEYAPVTQERAGGVMTVAELCEAAMTRSDNTAANLLTAQVGGP +AEVTGFLREKGDRVTRLDRWEPELNVR--DTRLDTTTPAAMADLTRRLLFDGGLDRAARE +QLTGWLRGNTTGDDRIRAGLPPAWQVGDKTGTGAHGEINDVAVAWPPDRAPVVVAVYTSP +RGATEEAGATALVEAARAVAGAf +>[subseq from] class A beta-lactamase n=1 Tax=Kineococcus sp. T90 TaxID=2696566 RepID=UPI001412D4AB +--AAEARLAQLEEEFDARLGLFALDTGSGRSL-THRADERFALASTYKALAAAAVLDRTT +--DAELDAVVTWRGSDLVDHSPVTGEHVEGGLPLRAVAEAAITVSDNTAANLLLDHLGGP +GGLEEDLRALGDSATEVDSREPAVNDHVPGRARDTTTPRAVATSLRAYALGDALEAGDRE +QLVRWLRANTTGDEQVRAGVPAGWVVGDKTGHAGHGNQNDIAVVWPAGGAPWVLAVLTDR +ADVDAESDDALLARATEVVVQE- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio thalassae TaxID=1243014 RepID=A0A240EKE6_9VIBR +--TLDESIASIEQRISGRIGVSVLDSSTQQQW-HYRGNERFPMMSTFKTLACAKMLHDAD +SGDLDKNALAPITSDKLIPWSPVTEKMVGSSITVSTACEATMETSDNTAANIVLHSIGGP +QGLTEFLRLNQDDVTRLDRIEPELNQVLSGDQRDTTTPNAMNTTLHRLLFEGAMNPGSKN +QLIAWMQGNTVSDSLLRSILPQGWSIADRSGAGANGSRGFTGAIWADNRKPLVISIYLTQ +TDLSMSERNQIINEIGGLIFQTy +>[subseq from] Beta-lactamase n=2 Tax=Nocardioides sp. YR527 TaxID=1881028 RepID=A0A1G9A9L1_9ACTN +------SIAALEQKHQRHLGVWARNMRTGRVI-EHRADERFPMLSTFKTLLAASILRDHP +--ARTLQQRLTWDAADVVVNSPITSLTVRNGLTVAQLAEAAITRSDNTAANELLHLIGGP +TGITRFARSLGDSVTRLDRWEPELNSAIPGDQRDTTSPRAIAQTYTKLVLGDALDRADRD +QLITWMLANQSTVTRFGAGVPAGWRLADKTGGGDYASRNDVGVTWTTDGAPIVIAALTRS +DDPAAPPLDVPLADIAATVC--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio chagasii TaxID=170679 RepID=UPI000FE3815B +-----ESIEQIESRVSARIGVAVYDSATKKAW-SYKGDERFPMMSTFKTLACANLLYDAE +NKGLDLDSKVSIKSEDLIVWSPVTKELVDKGISLRDACKATMTMSDNTAANIVLGGIDGP +NGLTQFLRSIGDSNTRLDHLEPELNHARPGDARDTTTPNSIVMTLNELMYGDTLSQASKA +TLKGWMMDNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWSEHRAPLIISVALTE +TEFTLQQRDKVINEVGQLIFDAy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces mirabilis TaxID=68239 RepID=A0A1I2EQH5_9ACTN +----------------------------------HRAAERFPLCSVFKTLAAAAVLRDLD +RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP +TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD +RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGAYGTSNDVGIAWTPDGAPVALAVLSTK +PAQNAAPDSPLVAAAASVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas salina TaxID=42565 RepID=UPI0005135026 +--DLERELGELERSADDRVGVALMNVATGAVA-SHRGHERFLFNSTGKCFIAAAVLARVD +EGRETLDRRIVIEEGDLVGWTPITEKRLGEPLTVAELCQAAVAWSDNAAANALIESVGGP +EAVTAFLRAIGDDTTRLDRVEPALNTDHAGDERDTTTPLAMMATLRTLLLGDALSPSSRH +QLASWMIEGKVGDARLRAGMPSSWLVGEKTGTNGVGNASDIGIAWPGDRGAVIAVAYTLM +PNVTGAERDETIAAVGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0004D395B0 +--AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGTTLHEPQRT +QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia TaxID=32008 RepID=UPI000B79D580 +--TAQAELTTLEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS +LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFARTSGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRA +RLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI0007C5AEE9 +-----QAAQEAEQSLQARIGLAVLDTADGQLW-QYRADERFPMASTSKALICSALLARGP +---GAMKTAWLIKEEAIQSYAPTTENLIGHYVSAAQLCAITMRNSDNTAANGVLEMLGGP +QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDALKTPDRD +RLTDWLRHNEVGGPLLRAGVPESWTVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE +TKASMEARNAAIAAIGKVIAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. RU38E TaxID=1907313 RepID=A0A239KF09_9PROT +---MRKDIEALEKARGGRLGVAVLDTASGRAM-DWRGDERFAMCSTFKFLLAGHVLALVD +AGQERLDRTLPVPPKKLLDWSPATTPHAGGNMDIAALCHGIITQSDNSGANILLEATGGP +GALTAWLRQLGDTITRCDRPEPTANLVPGGELRDTTTPVSMLGLMRIILLGNALSAPSRT +QLTDWLIANTTGDTRLRAGLPAGWKVGDKTGAWDD-AANDIAIIWPKGAAPLLITSYYRQ +PDLDGKGRNAVLAEVGRIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. Leaf307 TaxID=1736331 RepID=UPI0007029136 +-----AAFAALEERYAARVGVVAIDTATGETL-AHRADERFPHASTVKALAAAVLLDRTT +--PSELERVVPVRRTDLVDYSPVVEQRVGRGLTLGAAAEAAVRVSDNTAGNIVLEAIGGP +DGLRRALRGLGDRVTDPRRTEPTLNRFEPGDDRDTTTPRALATTLRTLAVDDTLAPADRR +LLLRWMSGNETGDTLVRAGVPDDWAVADKSGSGAYAARNDVAVVTPPGRAPVVVAVLTRS +EDVDAVARDALVAAAAGVVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio alginolyticus (strain ATCC 17749 / DSM 2171 / NBRC 15630 / NCIMB 1903 / XII-53) TaxID=1219076 RepID=A0A2I3CT28_VIBAX +-sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNAILNTLRTLIEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLVAQISQLILQKy +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520JCV5_SPHSX +--SAADELAGIEKASGGKMGVCVLDTATGATL-AWRADARFPFCSSFKAPLAAFVLWKAD +RGQLRLDRSIRYDAADLLSYVPITRAHVADGMSVEQLCAAAVAYSDNTAANLLLRETGGP +AALTAWMRARGDRAFNLASNEPRLNLSRYGDATDTTTARAMAESYRRFVLGDVLTPASRT +KLAGWLVANTTGDRRLRAGLPHAWRVGDKTGTFG-GSTIDIAVAWPPARPPLVIAGLITG +PN-DTASAERALVQVARTA---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. WAC 06725 TaxID=2203209 RepID=A0A429IGH6_9ACTN +----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD +HDGSQLARVIRYTEADVTKHAPVTKDHIATGMTIRDLCDATIRYSDNCAANLLLRELGGP +TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA +LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDGAPVLLTALTHK +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000A2DF188 +-----QAAQEAEQSLQARIGLAVLDTADGQLW-QYRADERFPMASTSKALICSALLARGP +---GAMKTAWLIKEEAVQSYAPTTENLIGQYVSAAQLCAITMRNSDNTAANGVLEMLGGP +QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDALKTSDRD +RLTDWLRHNEVGGPLLRAGVPESWTVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE +TKASMEARNAAIAAIGKVIAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI0005F90F12 +-----QAAQEAEQSLQARIGLAVLDTADGQLW-QYRADERFPMASTSKALICSALLARGP +---GAMKTAWLIKEEAVQSYAPTTENLIGQYVSAAQLCAITMRNSDNTAANGVLEMLGGP +QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDALKTSDRD +RLTDWLRHNEVGGPLLRAGVPESWTVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE +TKASMEARNAAIAAIGKVIAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. SBT366 TaxID=1580529 RepID=UPI00066C58E4 +---FAAEFEALEQEYGSTLGVYALDTGSGDEV-AFQEGERFAFASTFKALLAGVVLSENS +--LEEMERVVTFDEEVLVPHSPVVEEHLDSGMSLLELCDATVRFSDNAAANLLLDEIGGP +AGFTERLGETGDDVTVLERYEVEMSSAVPGEVRDTSTPEAMASSLEAFTLGDVLPEDRRE +VLVDLLVRNTTGDDLIRAGVPEGWVVGDKTGNGGYGTRNDIAVLWPEEGDPIVLAVMSSV +GVEDAEHDDALIAEATEVVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Tatlockia micdadei TaxID=451 RepID=UPI0009EF716B +--SIDKKLAKLESSSGGRIGVYAINTTNNTHL-EYRANERFPMGCTSKVMGVAAVLKKSM +KDNLLLSKKVTYTKNDLTNWNPITEKNLDTGMSVKELCAAAISYSDNTAMNLLLKQLGGL +EGMNAFARTIDDDSFRQTHWPGEAMSGGQNNTDDSSTPAAMATSLKKLAFTDALAKPQRE +LLLTWLKANTTGDARIRAGVPKGWLVGDKTGTGYYGTTNDIAIIWPPKCDPIVMAVYYTS +NNKNTSKREDIVASTTRIILDE- +>[subseq from] Beta-lactamase class A n=1 Tax=Prauserella rugosa TaxID=43354 RepID=A0A660CK09_9PSEU +--DVAGELAAVEQRFGGRLGVYAVDTGSGALV-QHRQRERFLMASTAKLPIVAATLGRGV +----PLDRSVPVRQEDVLEYAPVTQERAGGVMTVAELCEAAMTRSDNTAANLLTAQVGGP +AEVTGFLREKGDRVTRLDRWEPELNVR--DTRLDTTTPAAMADLTRRLLFDGGLDRAARE +QLTGWLRGNTTGDDRIRAGLPPAWQVGDKTGTGAHGEINDVAVAWPPDRAPVVVAVYTSP +RGATEEAGATALVEAARAVAGAf +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI0006A5956C +-sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNAILNTLRTLVEGETLSYESRV +QLKIWMLDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLVAQISQLILQKy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 62 TaxID=1827599 RepID=A0A3D9M7Q4_9ACTN +-----ARLRRLEREHSARLGVFARDMRSGRTV-AYRANERFPMASVFKTLAVAAVLRDLD +HDGEFLARRLRYTTAYVERYSPITGRNVAGGMTVSALCDAALRFSDNTAANLLLGELGGP +TALTRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTSPYAIGVGCARLVLGDALERHDRE +RLTGWLLRNTTSAERFRRGLPADWLLADKTGSGRHGGADDVGVAWRPDGTPIVLAVLTTK +AEEDAPADDPLVAGTAALL---- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium gilvum (strain PYR-GCK) TaxID=350054 RepID=A4TCH4_MYCGI +----EERIAALAARHDARIGLYAADLDSGATL-AFGDTDTFAVCSTFKTYAAGAVLQRVQ +QGRLGLGDTVLIEAADIRPHSPVTEPRVGTAMTLAELCQAALQQSDNAAANGLLRVLGGP +SAITEFARSIGDDRTRLDRWEVELNSAVPGDPRDTSTPRALATGYQALLTGDVLDPAGRR +QLVDWMLANQT--SSMRAGLPAGYTSADKTGSGDYGSTNDVGIAFGPAGQRLLLAVMTRS +ASPDAPSLRPLIGELATLVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Lechevalieria atacamensis TaxID=531938 RepID=UPI000DC42ECE +-----DALVELEKKYDARLGVYAAGVG---TI-EHRADERFAFCSTFKGLAAAAVLHRNP +--MTHLDKVVTYTEADLMKSSAITKRHVQTGMKLRDLCDAAVRFSDGTAGNLLLRELGGP +AELTKYLRELGDDVTRMDRIEPAITEATPGDPRDTATPRSLGTDYQRLVLGNTLDQEKRG +FLTDLLERSVTGAKRIRAGVPQGSRVASKTGTGDYGTANDIAVVWQPNREPILIAIMSSR +SAADAKYDEALIAEAAAYVTK-- +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium damselae subsp. damselae TaxID=85581 RepID=A0A1X9U699_PHODD +--ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KYKSVLTHSVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIVETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTAHEPIVVSIYIQQ +SSASMDERNKAIATIGRQVFTYf +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium vaccae ATCC 25954 TaxID=1194972 RepID=K0UUH2_MYCVA +-----ERLHTLAQRHDAEIGVYAVDLVTQDTL-AFRADETFAVCSTIKTYIAAAVLQRTQ +TGELSLQDTVPIEPDDIRPHSPVTEPRVGTSMTLAELCQAALQQSDNAAANGLLGVLGGP +PAITAFARSIGDDRTRLDRWEVELNSAVPGDPRDTSTPRALGIGFRDILTGNVLEPAVRQ +QLLDWMRANQT--SSMRAGLPAGYTSADKTGSGDYGTTNDIGVVYGPAGQQVLLSLMTKS +ASPDAPSLRPLIGELATLVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DF1F531 +-------------------------LNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEVIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIV------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium marinum TaxID=1781 RepID=UPI000E3B930B +--DLESRFAELEQKYEARLGVYVPGTGATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP +--IAHLDTVITYNSADIRSTSPITEQHLETGMSIGGLCDATIRYSDGTAANLLLQDIGGI +AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALPPEKRD +KLIDWLGRSTTGAKRIRAGFPADWRXIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR +VGPEAPWCDPLVADAAKCVAD-- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6D1LUY6_ECOLX +---------------------------------------------TSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Arthromitus sp. SFB-turkey TaxID=1840217 RepID=A0A1B7LLQ7_9CLOT +---YSSEFKNLEESYGAILGIYAVDTGTGNVV-SYNADERFAYASTYKALAAGAILEKYS +--IEELENIVHFTEQDVLSYAPVAKDKVSTGMTIREICEAAVRQSDNTAGNLQFDLIGGP +EGFKKSLEKIGDNITEPSRKETELNEATPGDIRDTSTPKQLALDLKEYVVGNVLSDDKKA +IFIDWMSNNATGNALIRAGAPSDWVVADKSGAASYGTRNDIAVVTPPGKDPIFVAILSKK +QGKDDKYDNKLIEDAARIVFKY- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFE6D65 +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMDVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGHGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea sp. p1410 TaxID=2603600 RepID=UPI0012FA82E1 +--NVDRELRALEQSFDGRIGAYAVDTATGKTV-GYRAGEIFPLLSTFKAPLCAAALHRAR +TERGLMSKRVTWTKEDLKPNSPVTEKHVEDGLTVAELCEATITLSDNTAGNMVLKQIGGP +GGLTRYFRSLKDPVSRLDRWETELNDWKPGEKRDTTTPAAISRDLRAVSAGNALHPKDRE +QLNAWLVASKTGGERIRAGLPKSWTVGDKTGTNTIGGGNDIAVIWPGKSKPIIMSVYTTR +ETP--AVDNTVLAKTATILA--- +>[subseq from] Beta-lactamase n=1 Tax=Actinosynnema pretiosum subsp. pretiosum TaxID=103721 RepID=A0A347Q2T1_9PSEU +------AFAALEQRFDARLGVYALDTGSGRVV-AHRADERFAYASTFKALAFGALLAERS +--VADLDERITFTGEELVTYSPITEGKVDTGMTLREVADAAVRHSDNTAGNLLLRELGGP +AAFERALRAIGDTTTSPARVETELNEAVPGDPRDTSTPEALAADLRRYAVADVLADDRRE +LLVSTMRANTTGDEAIRAGVPLGWVVADKTGSARYGGRNDIAVLWPPDRAPIVLAVLSGK +ATADAEHDDALLAEATRAVVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Geodermatophilus sp. Leaf369 TaxID=1736354 RepID=A0A0Q5VBG7_9ACTN +------GVADLEAAHGARVGAWVLDTGTGQVL-EHRAEERFAHASVLKLLLVGLVLDRVT +--DAELDAVVPIEADDVLEYAPVTSEHVGTGLPLREVMEAAIVVSDNTAANLLIERLGGP +AAVQAAVRELGNEVTDVDRTEPDLNEATPGDPRDTSTPAALGASIEQLVLGDVLPADRRA +LLEQGLRDNTTGDAAIRAGVPADWTVGDKTGSGGYGTRNDAGVVWPADGAPLVVVLLTDR +GTAGATSDDGLLADVTRLVVA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudomonas putida TaxID=303 RepID=A0A3R9D3X8_PSEPU +-----QAAKEAERALGARVGYAIHDTDNGRTW-QYRADERFPMASTVKVLVCSALLHQGP +---VSLARTVHIQEHDILPYAPVTQGMVGEDVSASRLCAITLETSDNTAVNGVLKALGGP +ATVTAFLRSIGDQTTRADRSEPELNEGRPGDERDTTSPQAMQRTLEALVLGTALDKAAQA +QLTRWMESNKVSGTLLRNGLPNDWRIADRSGSGGFGSRGVVAVMWPPGRGPIVAAIYLTQ +TQATLEQQDAAIAAIGRSL---- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 62 TaxID=1827599 RepID=UPI000E226833 +-----ARLRRLEREHSARLGVFARDMRSGRTV-AYRANERFPMASVFKTLAVAAVLRDLD +HDGEFLARRLRYTTAYVERYSPITGRNVAGGMTVSALCDAALRFSDNTAANLLLGELGGP +TALTRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTSPYAIGVGCARLVLGDALERHDRE +RLTGWLLRNTTSAERFRRGLPADWLLADKTGSGRHGGADDVGVAWRPDGTPIVLAVLTTK +AEEDAPADDPLVAGTAALL---- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI000D0533C8 +--ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KDKSVLTHSVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAAGGP +EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ +SSASMDERNKAIATIGKQVFTYf +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. ITM-2017-0098 TaxID=2099692 RepID=A0A2S9FC79_9MYCO +---VEQRIDALGRRHSAQIGLYAIDLGSETSL-AYRDTESFAMCSTFKAYAAGATLQRAQ +QGRLTLNDAVAIEPGDIRPNSPVTEPRVGTTMTLAELCQAALQQSDNAAANGLLRVLGGP +PAITEFARSIGDDRTRLDRWETELNSAVPGDPRDTSTPRALGDGFRALLTGDVLDGGRQR +QLVDWMLGNQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVVYGPAGQRLLLAIMTKS +ATPDAPSLRPLIGELAALVLA-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFCA8C +--SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Geodermatophilus sp. Leaf369 TaxID=1736354 RepID=UPI000A71BB50 +------GVADLEAAHGARVGAWVLDTGTGQVL-EHRAEERFAHASVLKLLLVGLVLDRVT +--DAELDAVVPIEADDVLEYAPVTSEHVGTGLPLREVMEAAIVVSDNTAANLLIERLGGP +AAVQAAVRELGNEVTDVDRTEPDLNEATPGDPRDTSTPAALGASIEQLVLGDVLPADRRA +LLEQGLRDNTTGDAAIRAGVPADWTVGDKTGSGGYGTRNDAGVVWPADGAPLVVVLLTDR +GTAGATSDDGLLADVTRLVVA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia reimsis TaxID=2234132 RepID=A0A365QSU5_9BURK +--AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA +QLTEWMVGGARGATGIAAGVPPDWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. Marseille-P9652 TaxID=2654950 RepID=UPI0012E80F22 +---VYDRLDRLEREYDAQVGVFAADAATGRAV-AHRDGDPFAMCSTFKAYAVARVLQLAQ +RGDVDLRQPVVIDPAKLLPNSPVTESRAGGTMALAELCAAALQRSDNAAANLLLQTIGGP +SAVTEFARSIGDDRTRLDRWETDLNTATPGDPRDTSTPRALGEGIQSLLTATVLGEAQRR +QLEDWMRANVT--STMRAGLPPGWTTADKTGSGAYGSTNDVGIAYGPDGRRVLLALMTRS +ASANAAPLPALIAEVTRAVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000A2DC79C +-----QAAQEAEQSLQARIGLAVLDTADGQLW-QYRADERFPMASTSKALICSALLARGP +---GAMKTAWLIKEEAIQSYAPTTENLIGQYVSAAQLCAITMRNSDNTAANGVLEMLGGP +QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDALKTSDRD +RLTDWLRHNEVGGPLLRAGVPESWNVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE +TKASMEARNAAIAAIGKVIAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Nesterenkonia sp. Hz 6-5 TaxID=2587813 RepID=UPI001390FAC5 +--SITESFEELESRYDARLGVHAVDTGTGEEV-TWREDERFAYASTIKALAAGAVLDEVG +--VAGLETEVLVEEEDIVPHSPVTENHIGQTLTLREIAEAAVTVSDNAAANYLFDELGGP +DELDAALEDLGDDVTEVVRREPELNEATPGDDRDTTTARAITGSLREYLFGTVLDDEEKS +QLGEWLIDSETGATLIRANLPSDWTIGDRSGAGGYGTRGNIAAIWPTSGDPIVISVLSSR +DEPDAEHDDQLIAEAAELAIS-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A419YPL9_9ACTN +-dDLDSRLRGLERAHGARLGVFAHDTGSGATI-RYRADERFPLCSTFKPLAVAALLRAGV +----DLAATVRYTDRDVVDHAPVCG--LTRSLTVAELCAAAVEFSDNTAANLLLRLLGGP +SAVTRFCRSIGDPVTRLDRWEPALNSAEPGRPTDTTTPAALGRSYARLVLGSALAPPDRA +RLTAWLLGTTTGAARLRAGLPPTWRVADKTGTGGYGTTNDAALAWPPHRAPVVVTVLATK +PDPGAVADEPLLAAAAGSVA--- +>[subseq from] Beta-lactamase class A n=3 Tax=Burkholderia TaxID=32008 RepID=A2WFD7_9BURK +--AAQSALAALEQASNGRLGVAALDTSNGTRI-AHHARQRFPLCGTYAVVAAAAMLARAS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCVAMLQAGDKGAGNLLMGVLGGP +QAVTSFARESGDTTFRLDHWEPELNRAVPDDERDTSTPVAMVDTLQRLLLGEVLHEPQRT +QLTEWLTDSARGTPGIAAGVPPGWRVAGKTGTGGYGTTTDVAVVWPPSRAPLVMAVSFTQ +PRADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Microbispora bryophytorum TaxID=1460882 RepID=A0A544XYJ9_9ACTN +--DVAAALRALETSFKGRIGAYAIDTATGKTV-GYRAGERFALLSTFKAVAAGAVLAKTT +-DRELTRKVVHWTAGEVKPNSPETSKHVKDGMTLAELCRAAIIYSDNTAGNMLLKRIGGP +RGLTRYFRTLKDPLSRLDRWETELNDWSPKEKRDTTTPASVARDLRALTTGGALGAKDRS +RLIGWLRGNTTGDARIRAGLPKTWIVGDKTGTGGYGAANDIAVVWPAKGAPIVMAISTNR +RAAAGATDDKVIAKTATVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000756F38F +----RSELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVIAAAAILARAS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQAGDKGAGNLLMNVLGGP +QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGNTLQQAQRA +QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ +AQADAAARADVVASAARIAT--- +>[subseq from] class A beta-lactamase n=1 Tax=Endozoicomonas atrinae TaxID=1333660 RepID=UPI000825F925 +-----ELISDLENRYEGQIGVAVLDTSDQSLW-HYQGNTRFPLMSTFKTLACAKLLADVD +QQKQKLTTESLIERESLVTYSPVTEPLVGQKITLEQACEATMSTSDNTAANLVLAGIGGP +QKLTDFLRSAGDSITRLDRIEPELNESHPGDNRDTTTPLAITNTLNQLILGNTLSDVSRA +QLKTWMMGNQVADNLLRSVLPEGWSIADRSGAGGHGSRGITTIVWSKKRLPLIISIYMTG +TNASFEERNQVIVKTGQAVFHHf +>[subseq from] Beta-lactamase OXY-1 n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A644SR34_9ZZZZ +-kDLQRMLAELEASSGGRLGVAASVSNGDKIL-SYRGNERFPMCSTFKVLAAAAVLRDKT +---NILEQRIHFAKSDIQPWSPVTEKHLEDGMTVSELCEAMLQHSDNTAANLVLAQLGGP +AGLTSIARSFGDTTFRLDRWEVELNTAIPGDARDTTTPLAMRRTLNGLLCGNQLKALAKK +QLTDWMLGCATGAGRIPAGAPQGWRSAHKSGSGENGTANDVGVLLPPKNKPLTVALYLTG +SRLTGPENDKILAQATRLVC--- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A3B7QVI9_STRFR +---LTGQLRALEQEYAARLGVFALDTASGATV-SHRAGERFPMCSVFKGLAAGAVLRDVD +RHGEFLGRRIRYTAEFVEAYRPVTGKNIANGLTGAELCAAAVSESDNGAGNLLLRELGGP +TAITRFCRSLGDDTTRLDRWEPELNTAEPWRTEDTTSPRAIGMTYGRLLLGRALAARDRE +RLWDWLVANTTNTERFRKGLPADWILADKTGGGSYGVANDVGVVQPPGRSPLVLAILSTK +LDPQGPTENPLVARAAALVA--- +>[subseq from] Beta-lactamase n=2 Tax=Acidocella sp. MX-AZ02 TaxID=1214225 RepID=K5YKI9_9PROT +---ATSFLAESERKTGGRIGVHARNLATGRTL-SWRADERFVMCSTFKMSLVACVLSRVD +KGDEQLGRFVHYGVAQISNYAPVARLHLAEGMTVEAMCQAAIEVSDNTCADLLLMSVGGP +AALTRFWRGEGDEVTRLDHTEPRLNFSPPGDPRDTTTPAAMAGDLQRFLLGDALSPTSRA +RLTGWMLNCQTGGALLRAGLPKGWEVADKTGNNGKDALGDIAVAWPAPDRPIVICAYTQG +GHPKPEILPPILAGVGRMV---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D007258 +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. GXS13 TaxID=1730094 RepID=A0A0V7Z424_9RHIZ +--ETEPALDAIERRLGGRLGISVG-TPERILI-SHRAGERFPMCSTFKVLAVAAVLARVD +ARSESSDRVIAFGPGDLLSYAPVTRKALDAGMTVSDLCAAAIEWSDNSAANLLLTALGGP +RALTQWLRGFGDPITRLDRTEPTLSTSLPGDPRDTTSPAAMRETLGRVLLGSALSPSARA +RLEAWMVASRTGLKRLRAGLPPDWPVGDKTGTGDNGTFNDVAILRPPGHAPVFACVYITG +AEAPAEAVEAAYAEIGRLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodovulum sulfidophilum TaxID=35806 RepID=A0A0D6B6M1_RHOSU +--TLADTVERVESRLGARVGVSLVDTGSGLSW-THRENERFLMNSTMKVPLCGAVLARRD +AGDLSLQAELPVRKSDLLAYAPVTEKRAGGEMTIAELCLAAIDMSDNTAANLLIAHLGGP +QAVTRFFRSAGDTISRLDRNEPELNTFNAADLRDNTTPAAMTETLRGLLLGDILSRSSRG +QLAEWMSHGGVTGNLLRAEAPEGWVILDKSGSGTH-TRNLVALVTPVDGSPWIVTIFVSD +VDADSQTRNRALQDVGRAAM--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. IS-1496 TaxID=1772284 RepID=A0A101AKG1_9MYCO +-------VENLERANNAVIGVFAQNLDTGRTV-AHRAQESFAMCSTFKAYLAAQILQLVG +RGERSLDQRLSVNAADLQPNSPRTEPRVGGEMTLTELCQAILQVSDNAAANILLRNVGGP +PAVTAFARGIGDPRSRLDRYEIELNSAVPGDPRDTSTPEALAGGFRAILTGEALAPPQRR +LLEDWMRANET--SSMRAGLPPGWTTADKTGSGDYGTTNDVGIAYGPQGQRLLLAVMTKT +ATPDAENMRPLVGEVTAAVF--- +>[subseq from] Beta-lactamase n=1 Tax=Sagittula sp. P11 TaxID=2009329 RepID=A0A2K8WAW1_9RHOB +--TLSDTVAQVEERLGARVGLSLVDTGSGLTW-AHREDERFLMNSTVKVPLCGAVLARRD +AGELSLAEALPVTAEDIVSYAPVSEQKVGQTMTLAELCLATIDISDNTAANLLIGRLGGP +EAVTQAFRDSGDEVSRLDRLEPGLNAFAPGDPRDTTTPAAMSATLSRILLGDVLTAESRD +QLSDWMSYGGVTGALLRRDAPESWQIFDKSGAGTH-TRNIIAVVIPDDASPWIVTIFVSD +TDADFDTRNAALQEIGSAVM--- +>[subseq from] class A beta-lactamase n=2 Tax=Burkholderiaceae TaxID=119060 RepID=UPI00080B6BE7 +--RAQAELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNAVGPGDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGTAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000841FD1F +----RSELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYEVVAGSPMTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP +QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA +QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ +AQADAAARADVVASAARIAT--- +>[subseq from] Beta-lactamase n=2 Tax=Mycobacteriaceae TaxID=1762 RepID=A0A5N5V9I5_MYCPH +-----TAIRALEQRHNARIGVYAVNLATGRTV-THRAQEPFAMCSTFKTYAAARVLQMAE +RGELSLTDPVFVDPAAIVRHSPRTEPRAGGDMTLDELCQAALQISDNTAGNLLLQTIGGP +QAITAFARSIGDERTRLDRWEIALNSAEPGDPRDTSTPEAIGGGYRALLTGDALGAPQRE +LLVRWMRANET--SSMREGLPAGWTTADKTGSGDYASSNDVGVAYGPRGERLLLALMART +AGPDAPTLRPVIGELAG------ +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. 3519A TaxID=2057184 RepID=UPI000C7C68F9 +---VADRIAALERRHNAYIGVFAVDLVGGRSF-SHRGQQPFAMCSTFKAYAAGLVLQMVE +QGQLTLDQQVFVDPAGVVANSPRTEPRAGGSMTLDELCQAALQVSDNTAGNLLLTTIGGP +PAVTAFARSIGDQASRLDRWETELNSAIPGDPRDTSTPEALGGGYRTLLTGAALAPPQRQ +QLEDWMRANET--SSMRAGLPQGWTSADKTGSGDYGTANDVGIAYGPEGQRLLLAMMTRS +QL-SDPQAASMRPEIG------- +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI00137C15E4 +-----QAAQEAEQSLQARIGLAVLDTADGQLW-QYRADERFPMASTSKALICSALLARGP +---GAMKTAWLIKEEAVQSYAPTTENLIGHYVSAAQLCAITMRNSDNTAANGVLEMLGGP +QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDALKTSDRD +RLTDWLRHNEVGGPLLRAGVPESWTVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE +TKASMEARNAAIASIGKVIAQ-- +>[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea sp. C10 TaxID=2600577 RepID=A0A5C8JQQ9_9ACTN +---VRAELRRLEASYQGRIGAFAIDTGTGKTF-GHRAGERFPSNSTFKAVLCGAILDKAR +TDPGLMKRVLRWTKKDVVDHSPVSGENIRNGMTPDRLCHATITQSDNTAANVLLKQIGGP +AGMTRYYRSLGDRAGRLDRWETELNDWKPGEKRDTITPASMARDLKKITVGDALVAADRK +RLTDWMRATETGKERIFAGLPKGWTAGDKTGTGGYGTASDIAIAWPPSGAPVIIAVYIQR +PSADAEVDNGVIARTASLLV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces alfalfae TaxID=1642299 RepID=A0A1P8TUL4_9ACTN +---LTGQLRALEQEYAARLGVFALDTASGATV-SHRAGERFPMCSVFKGLAAGAVLRDVD +RHGEFLGRRIRYTAEFVEAYRPVTGKNIANGLTGAELCAAAVSESDNGAGNLLLRELGGP +TAITRFCRSLGDDTTRLDRWEPELNTAEPWRTEDTTSPRAIGMTYGRLLLGRALAARDRE +RLWDWLVANTTNTERFRKGLPADWILADKTGGGSYGVANDVGVVQPPGRSPLVLAILSTK +LDPQGPTENPLVARAAALVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000752A9DD +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPARAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00016A59EE +--AAQSQLDALEQASNGRLGVAALDTVTGARI-AHRSRERFPLCGTFAVVAAAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGSANGVAGIRTGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PGADAAPRADVVAEAAR------ +>[subseq from] Class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A3G6HIJ0_ALCFA +-----QAAQEAEQSLQARIGLAVLDTADGQLW-QYRADERFPMASTSKALICSALLARGP +---GAMKTAWLIKEEVVQSYAPTTENLIGQYVSAAQLCAITMRNSDNTAANGVLEMLGGP +QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDALKTSDRD +RLTDWLRHNEVGGPLLRAGVPESWTVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE +TKASMEARNAAIAAIGKVIAQ-- +>[subseq from] Class A beta-lactamase n=1 Tax=Saccharopolyspora sp. 5K548 TaxID=2530386 RepID=A0A4V2YYD4_9PSEU +------NFAGLEHRFHARLGVYAVDTGTGETI-AQRADERWAYASTHKVFSAYAVLRRNT +--VEGLQRRIHYTREDLQPYSPVTEQHVDTGMTLREVVVAAVRDSDNTAGNLLFRELGGP +AGLQQELRDLGDTTTHVDRIETELGETAPGDIRDTTTPRAFAADLRKVALGDALPADKRE +ILLSAMRNSPITTKLVQAGVPADWQVEDKSGSADFGTRNDIAVVRPPGRAPIVIAVMSDR +ADRDASYDDALVAEATRLAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00112DACC1 +----RSELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQAGDKGAGNLLMNVLGGP +QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA +QLTDWMTAGAPDATGIAAGVPPGSHVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ +AQADAAARADVVASAARIAT--- +>[subseq from] Beta-lactamase n=1 Tax=Lentzea albida TaxID=65499 RepID=A0A1H9JTA7_9PSEU +-----DALVDLEKKFDARLGVFAT--GGRGTV-EHRADERFAFCSTFKGLAAAAVLHRNP +--MAHLDTVVTYTEAELMKSSAITRQHVRTGMKLRDLCDAAVRYSDGTAGNLLLREAGGP +AALTGYLRELGDTETRVDRIEPDLTSAVPGDPRDTATPRSLGTDYRRLVLGDALEPPKRD +FLVDLLERSVTGAKRVRAGVPEGSRVASKTGTGSYGTVNDIAIVWPPSGEPLLIAIMSSK +ASADAEYDEALVAEATAYVVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas prati TaxID=1843237 RepID=UPI0012F690A1 +--ALRATLAGLERQSGGRLGVAVRDRATGGVF-GYAADAGFAMCSTFKAPLVAAILHRVD +QGRERGDRAIAVGRDDIVPHAPFCETRVGARATVAELCEAAIVLSDNSAANLLLPIVGGP +GGLTAFLRRTGDPATLLDRIEPALNSATPGDPRDTTTPAAMAASLDRLALGPVLTPASRA +MLTGWMAASRTGLGMLRAGVPRDWRVVDKTGRGQTGTSAVIGVLWPPARAPMVIASYLTE +AKIEGAAADGVHRDVAQAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000587CDF3 +--SVVQTAQMLEQSLGARVGLAVLDTADGHVW-QYRANERFPMASTSKLVICAALLARGP +---GAMKAAWRVRQEAVLSYAPTTKDRVGEQIPADQLCAITMRNSDNTAANGVLEILGGP +AAVTSFLRSVGDTVTRLDRNEPSLNEAAPGDPRDTTSPYAMVQTLHRLALGDALKAAGRD +QLIGWLRRNEVGGPLLRAGVPERWAVADRTGAAAYGTRGVVAVMWPPERAPLVAAVYITE +TQASMDERNAAIATIGKAIA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=G5DDT2_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAHTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGG-------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Veillonellaceae bacterium TaxID=2049049 RepID=UPI0011C79524 +------TFTRLENDHQAKIGVYALDTESNKEV-SYHADDRFAYCSTSKVLMVGAVLRQES +--LEGIKKTVSYTQKDVLSYAPITSKYVETGMTLEELCVAALRVSDNTAANLLLAHIGGT +EGFKMSLRQIGDMVTEPARNEPMLNEAVPEDLRDTSTPHQLAVDFQSYILGDILTSEKKM +MLISWMAGNKNTDTLIRAGTPTDWLVADKSGTGGYGTRNDVAIITPPGRKPIILAILTTH +NDKELKADDQLVADIAKIVCEQf +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A1B1LEU7_BACTU +-------LSGLEEKHDARLGVFALDTGTNQMI-TYNGDDRFAYASTHKALAVGALLQTKS +--LADLDQIITYTQKDLDQYHPITEKYVNTGMTLRDLCDAVLRYSDNTADNLIFKLLGGP +SGLEKVLRGIGDTVTNPKRIEPELNVLLKGETQDTSTPKAMAANLQAFTLRNALSEEKRA +LLLDWMKRNTTGDEAIRAGVPAGWEVADKTGKGSYGTRNDIAVIWPENGKPIILAVMSDR +NSENASSTNELIADATKEVMK-- +>[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI000D58768F +--ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD +AGKLTLNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGS +AALTAYLQSIGDNVTRLDRNEPTLNEAVKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ +QLKTWMQDNKVADGLLRSVLPQGFQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ +TEATFDERNAAIVTIGKSVFDTf +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI0011B4F626 +-----QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE +NEGLDLGLKVDIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRSIGDRETRLDHIEPDLNHARPSDVRDTTTPNTMVKTLNELVYGNVLSEASKA +QLKTWLKDNKVSDGMIRSILPDGWKIADRSGAGAYGSRAITAIVWGETRAPLIISISLTE +SELTIPERDTVINEIGELIFDDy +>[subseq from] Class A beta-lactamase n=1 Tax=Agrobacterium sp. MA01 TaxID=2664893 RepID=A0A5Q2R7V4_9RHIZ +-----AAAKRVEQKLGMRVGLSVIDTGSGAVV-AYRDDERFAMASTFKSLACAAALSGGD +---AVLEQTTRITKADLRPHSPVTETRVGTSLSTRELCEITLRTSDNAAANAILKVLGGP +AEVTGFLRGIGDATTRLDRYEPEVNEAKPGDPRDTTTPEAMAQTLHRLLLDGALAPAARD +QLEAWMAANAVAGGLLRAKLPKGWTIADRGGAGGHGTRGVVALLRPPQGAPLVIAIYMDG +RKHPLKTRDAAIAEIGEAVFEEf +>[subseq from] class A beta-lactamase n=2 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0005D88A7A +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNAVGPGDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGTAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Pusillimonas harenae TaxID=657015 RepID=UPI001021262C +--ALNQALVELERTSRGRIGVGLLDTASGQVT-SYRGDERFLMLSTFKTLAAAYILARSD +QGVDKLTRRMSITDADILEYAPVTRRHIGPQMTLAELCHATITTSDNTAANLMHRSYGGP +QALTQFIRSLGDTVTRHDRYEPELNKPNASEPMDTTSPNAMTSTLNTLLFGTALKPESRQ +LLQSWLKANTTGDRRLRAGIPPNWIVGEKTGTASI-GANDAGFVQAPGGAAVIASVYLET +DAIAGPERDQIIATVGKRVAD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A3N7RQT7_9BURK +--AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAVAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEATLQFGDKSAANLLMSVLGGP +QTVTAFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANSVKGIRAGVPSDWRVAGKAGTGGYGTTTDVAVLWPQSHAPLVIAASFTQ +PGADASPRTDVVAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium acapulense TaxID=114977 RepID=UPI000749C9A8 +---IEDRLGEMERRQNALIGVFATNLGTGRTI-ANRAQDPFAMCSTFKTYAAARVLQKAE +RGELALTDRVTIEPGDLVPNSPVTEAHVGQTMTLAELCQAALQRSDNAAGNWLLRVIGGP +SGVTDFARSIGDERSRLDRWEIELNAAVPGDPRDTTTPEAIGNGYRAILTGNVLAEPQRR +QLEDWMRANQT--SSVRPVLPPDWATADKTGSGDYASTNDVGIAFGPAGERLLLAIMTRT +AAPDVPNDRQLVGEVASVLV--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. VPAP30 TaxID=1647102 RepID=A0A0H2MRE8_9VIBR +--AVEKAIERQEETLSARIGVAVLNVETGALW-SFRGDERFPLTSTFKSIACAKLLYDAD +QKTTELKKTVTVNREGLVAYSPVLEAYIDKEITLGDACQATMLTSDNTAANIVIASVGGT +DSITSFVRELGDENTRLDRVEPELNEALPNDPRDTTTPISMTNTLNELVFGAVLSENSRA +QLIDWMKSNEVTGNLLRSVLPVGWEIADRSGAGGFGARSINAVVWLDKKSPIIVSIYVSQ +TDASMDQRNLAIVEIGKSIFDLf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000751BC02 +--RAQSGLAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIEWMTASAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI000E1C7F3B +--ALVDIIKQQENALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KDKLALTYQVVIKKSDLVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDLRDTTTPIAIVETLNKLMLSDILTKPSQQ +QLITWMEGNQVAVPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ +SSASMDERNKAIATIGKQVFTYf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. XS-10 TaxID=2599297 RepID=A0A518RKR2_9SPHN +-------FDRIRAETGGRLGVAVYDTGTGRRY-FDGAEARFAMCSTFKVPLVAAVLARVD +RGELDLAREIRFSAADLLSYAPVVKENLAKGLSIEALCEAAVVMSDNSAANLLFGQIAGP +RGLTKFIREAGDTITRSDRDEPELNNVRDGEVRDTTTPEAMLWLMNRLLLGDILSAASRA +KLIGWMEASPTGKDRLRAGLPRSWRVGDKTGTSGEGYFNDIAIATPPGRKPVLITCYLDA +PGLDAAKANAAHARVGELVG--- +>[subseq from] Beta-lactamase,beta-lactamase TEM,Beta-lactamase n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A498RS12_9BURK +--TAQAELAALEKASNGRLGVAALDTSSSVRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP +QAVTAFAHDSGDPTFRLDHWEPELNKATPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA +QLTEWLTGGARSAAGIAAGVPSGWRIAGKAGTGGYGTTTDIAVVWPPSRAPIVMAVSFAQ +PQADAAARADVVASAARIVTGAf +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A107FUA6_9BURK +--AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAVAAMLARSA +LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP +QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA +QLTKWLLGTANSVKGIRVGVPSDWRAAGKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ +PGADAAPRADVIAEAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizomicrobium electricum TaxID=480070 RepID=UPI00142314B1 +-------------DTGGRLGVSVLDTGSGKRL-RHRATERFAMCSTFKLLLAAAVLKRID +TGKEDASRVIAYSKADHLVWSPVTEKHTA--LPVTDLVDAIVQVSDNTAANLLLDTIGGP +AGWTAFVRGFGDKTSRLDRTELTLNNADPGDPRDTTTPDAMLENLQKVLLGDVLTPASRQ +HLIDTMARSITRIKRLKAGLPKDWRIADKTGTGKHDTYNDVAIIYPPGRAPILACAYYTE +ATR--PDPENTLAEVGRAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Alcaligenes sp. EGD-AK7 TaxID=1386079 RepID=U1YEP2_9BURK +---VAQAAQAVEQSLQARVGLAVLDTTDGQLW-QYRADERFPMASTSKALICAALLARGP +---GAMKTAWLVKEEAIQSYAPTTENLIGQYVPASQLCAITMRNSDNTAANGVLEMLGGP +EAITSFLRSVGDMVTRLDRNEPSLNEARPGDPRDTTSPQAMVHTLQSLVLGDALKAPDRD +RLIDWMTHNEVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVMWPPERAPLVAAVYITE +TKASMEERNAAIATIGKAIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Herbidospora sp. NEAU-GS84 TaxID=2696284 RepID=UPI001372D303 +-----ADLRALETAFKGRIGLYALDTATGRTV-AYRSGERFPLASTFKGVLAAAVLDKKP +---DILGKRILIRKKDLLPNSPETAKHVGSRMTVAALARAAVTKSDNAAANLLLRQIGGP +KGLTGYFRSLDDHVSRLDRNEPGLNLWHPREVRDTTTPAAIAADLKALTVGGALDAGDRR +TFTGWLVANETGDKRIRAGLPKSWRIGDKTGTGGYGTANDYAVIWPKGSKPIIMAIYTNR +TDRNAAADESVIARAATIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F5E16D0 +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTSAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium hodleri TaxID=49897 RepID=A0A544W081_9MYCO +----GDQFAALERRYDAFIGTWAADLDGGRSV-ANRADDPFAMCSTFKAYAAGRVLQKDQ +TGALHLTDAVTIEAVDLVANSPITEPRVGQNMTIGELCEAALQRSDNTAGNWLLRIIGGP +SAVTTFARTLGDDRTRLDRWETDLNSAVPGDPRDTSSPRALGAGYQRLLTGDVLDAPRRA +QLERWMRGNQT--SSLRAGLPAGWTSADKTGGGAYGSTNDVGVVYGPDGRRLLLSIMTRS +RTDDAHDLRSLVAEVTTLVL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SDr-06 TaxID=2267702 RepID=A0A367HX57_9ACTN +--DVADELRRLETAQHVRIGAYALDTATGRSV-SYRGNEKFPSLSTFKAMVCAAVLGRAR +HEPGLLDKVVHWKASQEVANSPVTAGQGGKGMKVADLCHAAVTRSDNTAGNLVLGRIGGP +EGMTRYYRALGDAVSRLDRWEPDLNVWKPGEQRDTTTPAAMGRDLARTSLGSALVPADRA +RLNSWLRATVTGNERIRAGLPKDWTVGDKTGTSDYGSANDIAVAWPKSGRPVIIAIYTNH +LTADAPADSAVIASTTSTLV--- +>[subseq from] Beta-lactamase n=2 Tax=Pseudomonas TaxID=286 RepID=A0A5B0EUD5_9PSED +--DIEIQLQKLEREHGGRLGVALMNCSTGAIA-SHRGNERFLFNSTSKLFIAAAVLARVD +SGEETFDHRLVVSESDLGGWTPITEKQLGEPITVAELCQAAVAWSDNAAANVLIRSVGGP +EAVTAYLRSISDDTTRLDRYEPDLNEDHEGDERDTTTPLAMMKTLQLLLLGEVLLPSSRH +QLAAWMIEGKTGGARLRAGMPASWLVGEKTGTNGVGNANDIGVAWPADRGAVIAIAYTFM +PNASKEQCDKAIALIGKIAS--- +>[subseq from] Uncharacterized protein n=3 Tax=unclassified Pseudomonas TaxID=2583993 RepID=A0A656TCP1_9PSED +--------ASIEARTGGQIGVSVTALESGQSW-SHRGDERFPIASTFKAFSCGHLLALAD +RDKIELDTRVRFDETDLQSYSPITKDRVGGSMSLFELCSATTSMSDNTAANLILRHTGGP +LGFTTFMRSIGDAVTRLDRYEPELNDVGPGEERDTTTPMAAARSLETLLLGDSLSTHSRE +QLKAWLINNKVGGPLLRASLPESWKIADRTGSGGYGSRGVIAVIWPQGSEPVIVAVYLTG +TTLTLEERDATIAEVGAALV--- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. WL120 TaxID=2603887 RepID=A0A5C8RVZ2_9RHIZ +--SAAARIAAVEARLGGRVGVAFRD-ASGVFL-GHRAGEAFAMCSTFKVLAAAAILARAA +AGAETLDRRIAYGAADLQSYGPVTRAALANALTVEALCAAAIVWSDNTAANLLLDALGGP +AALTAWLRGQGDAVTRLDRTEPTLNTALPGDPRDTTSPSAITGTLERCLLGDVLTPPHRA +RLEGWMVACETGRTKLRAGLPLDWTVGDKTGSGDNATSNVVAILHPPGRPPILAGLFLTG +SAPPPATRDAAHAEIGRILVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D005A0A +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAL +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD4A702 +------AAQRVETELGMRVGFAVLDTGSGEVR-RYRANERFAMASTFKALACAAALSA-- +-GPSVLDKQTRISKADLRPHSPVTEKRVGTGLSTRALCEITLRTSDNAAANAILKAIGGP +AAVTTFLRGIGDDTTRLDRYEPELNEATPGDPRDTTTPQAMAETVGRLLLDRALEPKARD +QLEAWMAANAVAGGLLRAGLPKGWAIADRSGAGGHGTRGVIALLRPPEGAPLVVAIYMDG +RKHPLKVRDAAIAEIGAAIFAEy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SH65_9BACT +--TLSKAVQAEEARLAARIGVALFDAKDGTRW-AHRGDERFPLNSTHKSFSCAALLKQVD +RRVLALENVISIERASLVTYSPVMEKT-GGQVTLREACAASVSWSDNTAANIVTDAIGGP +QAFTVFMRDIGDQHTRLDRKEPEMNEATPNDLRDTTTPNAIVESLRRIILGDVLREDSRA +LLTDWMINDKVADALLRATLPRTWSIADKSGAGGHGSRSIVAVIWPKNRAPIVVGIYITQ +TTAPMVDSNAAIARLGSVLAD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. P44RR-XXIV TaxID=1921145 RepID=A0A4V6UGD2_9RHIZ +---QQQRLAALESKHPGRICVSILDLASGRRI-EHRAGERTLICSTFKTLIAALVLTRVD +KGEEKFDRRIRYSKSDLVESSPATGAQLENGMTIAQLCAAAMTLSDNTAANLLLASFGGP +KALTAFCRSLGDDITRLDRTEPALNYDTPDDQRDTTTAAAMLENLRRLLFTDVLSAASRS +QLAAWLITNKTGDTRLRAGVPKDWLAGDKDGNAN-----DIAVLWPTNRAPIIVTAYCEI +PGIPADERNSIIAEIGRIAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium marinum TaxID=1781 RepID=UPI000E3D8EDE +--DLESRFAELEQKYEARLGVYVPGTGATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP +--IAHLDTVITYNSADIRSTSPITEQHLETGMSIGGLCDATIRYSDGTAANLLFQDIGGI +AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALPPEKRD +KLIDWLGRSTTGAKRIRAGFPADWRXIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR +VGPEAPWCDPLVADAAKCVAD-- +>[subseq from] Beta-lactamase n=2 Tax=Agrobacterium TaxID=357 RepID=K2PB25_9RHIZ +------AAKRVEERLGMRVGLSVIDTGRGTVV-AYRETERFAMASTFKSLACAAALAGGN +---AVLEQTTRITKADLRPHSPVTEKRVGTNLSTRALCEITLRTSDNAAANAILKTLGGP +AEVTGFLRGIGDKTTRLDRYEPELNEATPGDPRDTTTPQAMAQTLEHLLLGDALAPAARD +QLEAWMSANAVADGLLRSKLPKGWQIADRSGAGGHGTRGVIAVVRPPPGQPLVIAIYMDG +KTHPLKARDAAIAEIGDAIFARy +>[subseq from] Beta-lactamase n=1 Tax=Pseudoalteromonas sp. NBT06-2 TaxID=2025950 RepID=A0A269PKC3_9GAMM +------IIEEQEHQLGARIGVSIYDVIDNKLW-NYNGNTRFPLMSTFKVLACAKLLADVE +KGLQSFDTSLVITASSLIKWSPITKNLIGKKMSLKQACSAAMIMSDNTASNMVLNGIKGP +KALTQFMRNIGDEVTRLDRIEPDLNEALDGDKRDTTTPNAMVKSLHKLLFGDALSQASKN +LLKQWMIDNKVTASLLRSILPDNWLIADRSGSGGYGSRGIVAVAWSDKRTPIIISIYLTQ +TDAPFSLRNKAIADIGKEIFTVy +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A1Z3Z0C0_BURCE +--AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELTHAAPGDERDTSTPVAMIDTLQRLVLGNTLPEPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium bacteremicum TaxID=564198 RepID=A0A1W9YVI8_9MYCO +--SLPEQFRELEARHNAFIGVYGVNLDSGSSV-RNRPDEPFAMCSTFKGYAAAAVLRRVA +EGELSLDKPVFVDPAGILPNSPVTEERAGGQMTLAELCQAALQRSDNLAANLLLATLGGP +RAITDFARSIGDDKTRLDRWEVELNSAIPGDPRDTSTPEALGHGYRNLLAGTALPPAQRD +LLDGWMRANQT--SSMRAGLPPDWTTADKTGSGDYATTNDVGVAYGPAGTRVLLSIMTRT +QSADAEGLRPLIGEVAALVL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A411T593_ALCFA +--SVVQTAQMLEQSLGARVGLAVLDTADGHVW-QYRANERFPMASISKLVICAALLARGP +---GAMKAAWRVRQEAVQSYAPTTKDRVGEQISADQLCAITMRNSDNTAANGVLEILGGP +AAVTSFLRSVGDTVTRLDRNEPSLNEAAPGDPRDTTSPYAMVQTLHRLALGDALKAADRD +QLIGWLRRNEVGGPLLRAGVPERWAVADRTGAAAYGTRGVVAVMWPPERAPLVAAVYITE +TQASMDERNAAIATIGKAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A0M1F3U4_STEMA +-----ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD +AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP +SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTGPAAMATSLARFAVGNGLQPASRQ +QFADWLIDNQTGDACLRAGLGTRWRVGEKTGSNGDDTRNDIAVLWPHGGAVWVVTAYLQG +ASVDYDQRAAVLARVGAL----- +>[subseq from] class A beta-lactamase n=1 Tax=Halomonas sp. HG01 TaxID=1609967 RepID=UPI0006148262 +--DLERELGELERSADDRVGVALMNVATGAVT-SHRGHERFLFNSTGKCFIAAAVLARVD +EGSETLDRRIVIEEGDLVGWTPVTEKRLGEPLMVAELCQAAVAWSDNAAANALIESVGGP +EAVTAFLRAIGDDTTRLDRVEPALNTDHPGDERDTTTPLAMMATLRTLLLGDALSPSSRH +QLASWMIEGKVGDARLRAGMPSSWLVGEKTGTNGVGNASDIGIAWPGDRGAVIAVAYTLM +PNATGAERDETIAAVGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI000D3C0E9C +-----ESIEQIESRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE +NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIGGP +NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TELTIQERDTVINEIGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Acetobacter persici TaxID=1076596 RepID=UPI000AB9FE82 +-------IAAYEKATGGRIGVYACNLATRQRL-TWRENDRFALCSTFKASLVALVLLRVE +QGKDRLDEAVPYTRADIERYAPVAQASLEAGMSVRALCQAAIEQSDNACANLLLARVGGP +ENLTRFWRSLGDQATRLDDWEPDLNRVPPGSVRNTTTPAAMAGVLEHLLFGNVLSASSRL +VLTEWLKRCQTGRNRLRAGFPAGWEVGDKTGTNGQDAAGDSAVAWPSPRTPLIVCVYTRG +GHPAEDQFRAAFAGIARLA---- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q3S672_ECOLX +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKTDLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVNNQVTGNLLRSVLPAGRNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGHSIFDVy +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. AU15512 TaxID=2015345 RepID=A0A228GIW2_9BURK +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS +LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTAFVRASGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLVLGNTLQEPQRA +RLTEWMAGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI0010FEE44C +--ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KDKLVLTHQVVIKKSELVTYSPVTEKWIGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSDILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTQHKPMVVSIYIQQ +SSASIDERNKAIAIIGKQVFTYf +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium psychrotolerans TaxID=216929 RepID=UPI00138D666C +------DLKGIEHRHRARIGAYAVDLGAAATV-EHRADERFAMCSTFKAYAAGRVLQLVD +QSRLDLRTPIPVNAADIVANSPVTEQRVGATMALAEVCEAALTRSDNAAGNLLLRTIGGP +GGVTAFARTLGDEQTRLDRWETELNSAIPGDVRDTTTPRGLCWGYRQLLTGTALSPSARA +TLDGWMRANVTSGPRFRAAVPAGWTTADKTGAGDYGSTNDAGLILGPARQRVTAVVLTRS +IDKDTPPLNAAISDTVRLILDSf +>[subseq from] Beta-lactamase n=2 Tax=Mycobacterium florentinum TaxID=292462 RepID=A0A1X1TVY8_9MYCO +--QVDDRLAELERQYDAYIALLATDLGSGRTV-AHRDDDPFAMCSTFKAYAAARVLQKVQ +RGELDLQQRVFIDPAALLPNSPVTAPQAGNTMALAQLCAAALQRSDNVAANLLLAQIGGP +PAITDFARSIGDERTRLDRWEIELNTAIPGDPRDTSTPRALGIGIQNLFTGTVLGDAQRS +QLEQWMRGNVT--SSMRAGLPPGWTTADKTGSGDYGSTNDIGMVYGPAGQRVLLSLMTRS +QSRDADALRPLIAEVTKSVF--- +>[subseq from] Class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A5Q0DMQ2_ALCFA +---VAQAAQELEQSLQARVGLAVLDTADGQWW-QYRADERFPMASTSKALICSALLARGP +---GAMKTAWLVREEAIQSYAPTAEDLIGQYVPASHLCAITMRNSDNTAANGVLEMLGGP +EAITSFLRSVGDTVTRLDRNEPSLNEATPGDPRDTTTPQAMVRTLQNLVLGDALKAPDRD +RLIDWLRHNEVGGPLLRAGVPESWAVADRTGAAAYGTRGVVAVMWPPERAPLVAAVYITE +TKASMEERNAAIATIGKAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea gerenzanensis TaxID=93944 RepID=A0A1M4EJS6_9ACTN +--QVKKELRALEASFKGRIGAYAIDTATGRTV-GYRSGERFPLLSTFKAPLCAAALHRAR +TEPGLMEKVVKWTAADLKPNSPTTEKHVEDGLSVAKLCEATITESDNTAANMILKQIGGP +AGLTKYFRSLKDPISRLDRYETELNDWTAKEKRDTTTPAAIARDLRLLTAGNALQAKDRE +QLNAWLIANKTGDARIRAGLPKTWKIGDKTGTNGIGGANDIAVVWPSGAAPIILAVYTHR +TV--AAADDAVVAKTATILA--- +>[subseq from] Beta-lactamase n=1 Tax=Tardiphaga sp. P9-11 TaxID=2024614 RepID=A0A5A7W9Z6_9BRAD +---APAALQTYERDTGGRIGVYAENLKTGAKI-EWRANERFVMCSTFKASLAACVLARID +RGEDKPDHMISYAAADLLEYAPVARDNLAKGLSVADMCKAIVELSDNACANMLLARVGGP +AALTAFWSRTGDSVSRLDHNEPLLNRSRPGNPQDTTTPAAMAGNIKRFVTGDVLTSASRD +RLTDWMVNCKTGDKRLRAGLPKTWKIGDKTGNNGKDAAGDIAVTWPKPDQPIVIAAYTQG +GAPTAPQFETVFKAIGEMV---- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderiales bacterium PBB4 TaxID=2015566 RepID=A0A257H361_9BURK +--------VALEKKVGGRLGVAFLNTSNGAMV-GHRLEERFGMCSTFKLPLAAAVLRKVD +QGALRLDQWVAYSASDIVAHAPVTQENLAKGMTVGALAEAAQTTSDNPAANLLLGLIGGP +AGFTGMLREAGDSVTRLDRMEPHMNAVARQDPRDTTTPSAMAATLVRILTSDWLTPDSRA +KLIDWMVATETGAKRLRAGFPTQWRAGDKTGTGMMDKYNDIAIAWPQGRAPLIVTAFYET +SKKMRDQDQAVLAEVGRIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075EEA35 +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTAFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIEWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. HI00D65 TaxID=1822216 RepID=A0A166AL45_9VIBR +-----ESIEQIESRVSARIGVAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDAE +HKGLDLDSKVSIRSEDLIVWSPVTKELVGKGISLRDACSATMTMSDNTAANIVLGGIEGP +NGLTQFLRSIGDSHTRLDHLEPELNHARPGDARDTTTPNSIVMTLNELMYGDTLSQASTS +TLTGWMMGNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWSEHRAPLIINVSLTE +TEFTLQQRDKVINEVGQLIFDAy +>[subseq from] Beta-lactamase n=1 Tax=Aeromicrobium sp. Leaf289 TaxID=1736324 RepID=A0A0S9R4Y0_9ACTN +---FSADFADLEEEYDARLGVYAIDTGTGQVV-EHRADERFAYASTIKALAVGALLHEKP +--RSVLDQTVELGEEDLVENSPELEKAVEEGLTVRELADAAVRYSDNTAGNLLFDLLGGP +EELQGVLREIGDETTIVSRIEPELNEAVPGDDRDTTTPEALATTLRAFTLGDAVNNGARA +MLTDLMVRNTTGDDLIRSGVPDNWEVADKTGAAAYGTRNDIAVLRRADGDPIVLVIMSSK +TEQDAEYDNDLIADATRVAVAGf +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI000907F6DD +---IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYVAARVLQMAE +HGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP +AAGTAVARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG +LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS +QAHDP-KAEN------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. BK042 TaxID=2512137 RepID=A0A4R3FKR3_9ACTN +---APKGLRELEARHGARLGVFARNIVTGRTV-RYRAGELFPMCSLFKTLASAAVLRDLD +RDGEFLSRRIHYTDADLPKGSDKTREHLADGMTVAELAEVAITFSDNGAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWETELNSAEPWRITDTTSPYAIGRTYGRLVLGDALDGPDHA +LLTHWLRNNTTSGTRLRAGLPPAWTVADKTGGGSYGTNNNVGIAWTEDGTPLLLAVLSTL +PAQDAARDDVLIRDTAALLA--- +>[subseq from] Beta-lactamase n=2 Tax=Actinomycetales bacterium TaxID=1911520 RepID=A0A4Q5TJ04_9ACTO +---FSADFADLEEEYDARLGVYAIDTGTGQVV-EHRADERFAYASTIKALAVGALLHEKP +--RSVLDQTVELGEEDLVENSPELEKAVEEGLTVRELADAAVRYSDNTAGNLLFDLLGGP +EELQGVLREIGDETTIVSRIEPELNEAVPGDDRDTTTPEALATTLRAFTLGDAVNNGARA +MLTDLMVRNTTGDDLIRSGVPDNWEVADKTGAAAYGTRNDIAVLRRADGDPIVLVIMSSK +TEQDAEYDNDLIADATRVAVAGf +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium monacense TaxID=85693 RepID=UPI0007E97D15 +-------LDALERANNAVVGVFAVNLDTGRTV-AHRAQESFAMCSTFKAYLAAHVLQLVG +RGERSLEQGLYVDAADILPNSPRTEPRVGGEMTLAELCQAILQVSDNAAANILLRDVGGP +PAVTAFARGIGDPRSRLDRYEIELNSAVPGDPRDTSTPEALGGGFRTLLTGDVLAPPQRR +LLEDWMRANET--SSIRAGLPPGWTTADKTGSGDYGTTNDVGIAYGPQGQRLLLAVMTRS +ATPDAENMRPLIGEVTAAVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075B2D5B +--SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDQGAGNLLMDVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMTAGAR-GDGIAAAVPPAWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. IS-3022 TaxID=1772277 RepID=A0A124EMB2_9MYCO +----DARIGELERQHNALIGVFAVNLDTGRTI-AHRAQEPFAMCSTFKGYAAARILQKAE +RGELALSDRVAVEQSDIVPNSPVTQTRVGQTMTLAELCEAALQRSDNAAGNLLLGVIGGP +PAITDFARSIGDQRSRLDRWEVELNSAVPGDPRDTTTPEAIGGGYRSMLTGAALAEPQRR +LLEDWMRANQT--SSVRPALPPGWTTADKTGSGDYGSTNDVGVAHGPDGRRLLLAVMTRS +AGNDAPNMRPLIGELAALLV--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium asiaticum TaxID=1790 RepID=UPI0007EF1E5A +--DLSHQFDQLERRYEGRLGVYVPE----PAI-AYRADERFAFCSTFKAPLAAAVLHQYP +--LDHLDKLVSYNRSDINSVSPVTEQHVDTGMTVGQLCDAAVRYSDGTAANLLLAEVGGP +AGFTAYLRTLGDNVSRLDQPEPQLNRDAPDDPRDTTTPHAIALVFQQLLLGDDLPADKRV +LLVDWMTRSTTGGKRIRAAFPPDWKVADKTGSGDYGRTNDVAVVWSPSGAPHVIAIYSDF +VGYGAQPNDAFVADAARIVAS-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrionales bacterium (strain SWAT-3) TaxID=391574 RepID=A5KWL1_VIBBS +-----ESIEQIESRVSARIGVAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDAE +NKGLDLDSKVSIKSRDLIVWSPVTKELVDKGISLRDACSATMTMSDNTAVNIVLGGIGGP +NALTQFLRSIGDSNTRFDHLEPELNHARPGDARDTTTPNSIVMTLNELMYSDTLSQASKA +TLKGWMMGNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWSEHRAPLIISVALTE +TEFTLQQRDKVINEVGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI0013EF7A68 +--SVVQTAQMLEQSLGARVGLAVLDTADGHVW-QYRANERFPMASISKLVICAALLARGP +---GAMKAAWRVRQEAVQSYAPTTKDRVGEQISADQLCAITMRNSDNTAANGVLEILGGP +AAVTSFLRSVGDTVTRLDRNEPSLNEAAPGDPRDTTSPYAMVQTLHRLALGDALKAADRD +QLIGWLRRNEVGGPLLRAGVPERWAVADRTGAAAYGTRGVVAVMWPPERAPLVAAVYITE +TQASMDERNAAIATIGKAIA--- +>[subseq from] Beta-lactamase n=2 Tax=Listeria grandensis TaxID=1494963 RepID=W7BE56_9LIST +--DTTAQLKNLEKKYQATLGVYAIDTGFGETF-AHNGDQRFAFASTIKAFLGGILLKNLS +--WDELNKTIMYTEDDLVSYSPITEKHVDTGMALKDIISAAIEYSDNTAANLMFNQLGGP +KGFQEQLRNLGDTVTNSSRIETDLNSAIPGDIRDTSTPKTMAENLKKLLFEDKLAPDKLK +FYNQILIGNATGDTLIRAGVPANVKVGDKSGAASFGTRNDVAVLYPPHRSPIILVVYSNK +ANEDDEYDDALIADAARVMSSHf +>[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia phymatum TaxID=148447 RepID=B2JET9_PARP8 +---ARERFEQLEASSGGRLGVAALRTADGSYV-GYRESERFPMCSTFKLLAVALILKRSM +AERGLLEERIRYGDAQVVAHSPVTKRHAGGEMTVGELSAAALQHSDNTAANLLLTSLGGP +EVLNQFALSIGDTWFDLVRNEPEVNASVPGDMRDTTSPRAMLLDVQKLLLDDVLGARERE +QLKAWMLGNTTGATRIRAAVPAGWLVADNTGSGDYGTANDVAVVYPPSSAPLVVAIYFTG +VTKETPPQDAIVDEAARIVFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium hippocampi TaxID=659824 RepID=UPI0013955A6F +----DERIEAFERQHNVVVGLSAVELPSGRWL-AHRGKERFAMCSTFKAYAAGAVLQRAD +RAELALNEAVNIEPADIITHSPVTGTRVGATMTLAELCQATLQQSDNAAANLLLRVLGGP +AAITTFARSIGDDQSRLDRWETELNSAVPGDPRDTTTPFAVGAGYRNLLTDDVLSTDGRR +RLEDWMLANQT--SSMRSGLPARWTSADKTGSGGYGTTNDVGIAYGPEGQRLLLAIMTRS +AAPDAPNQRPLIGELAALAV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2L1J0W6_KLEPN +------------------------DLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGXRGARGIVALLGPNNKA---------- +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Salmonella enterica TaxID=28901 RepID=A0A3W2N4L9_SALER +----------------------------------------------SKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces carminius TaxID=2665496 RepID=A0A2M8LR84_9ACTN +--SVAGRLRALERAHSARLGVFALNPATGAAV-LHRADERFAICSVWKPLAVAAVLRDRD +--EAFLGRRVRYTEADLVAHSPDTGRNLANGMTVAELCEATVCRSDNTAGNLLLRELGGP +RAVTRFCRSIGDQVTRLDRWETELNSAEPGRVTDTTSPRAVAQTYRRLITGGALDEPDRE +RLTDWLRTNETNGRSFGAGLPDGWTSADKTGAGRHGSNNDVGVAWTPDGRPVVLAVLTAK +EKETAEPDYPLVAKTAELLA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. AU6039 TaxID=2015344 RepID=A0A228PGL7_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARESGATSFRLDHWEPELNNAAPDDERDTSTPVEMVDMLQRLLLGNTLQEPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas putida TaxID=303 RepID=UPI00104C111F +-----------EQKLAARVGYAIHDTGTGRWW-QHRADERFPMASTVKLLVCSALLHQGQ +---AALKKPWRVQQKDILPHSPVTQGMVGKQVAASDLCAATLKTSDNAAANGVLEVLGGP +ETVNTFLKEIGDQTTRSDRNEPSLNEGLPRDKRDTTTPRAMATTMQSLLLGSALKEGQKQ +QLKEWLLSNEVGGPLLRAGIPDDWQIADKTGSGGFGTRGIVAVMWPPQRAPIVAAIYLTE +TTASLEQRNAAIAEIGRAMVK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. A1499 TaxID=2563104 RepID=A0A4S3GM14_9ACTN +---LTGHLRALEQEYAARLGVFALDTASGATV-SHRAGERFPMCSVFKGLAAGAVLRDVD +RHGEFLGRRIRYTAEFVEAYRPVTGKNIANGLTGAELCAAAVSESDNGAGNLLLRELGGP +TAITRFCRSLGDDTTRLDRWEPELNTAEPWRTEDTTSPRAIGMTYGRLLLGRALAARDRE +RLWDWLVANTTNTERFRKGLPADWILADKTGGGSYGVANDVGVVQPPGRSPLVLAVLSTK +LDPQGPTENPLVARAAALVA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=A0A1S1L0J9_MYCCH +--------TALEDWYGARIGVYAVDLDSLRTV-EHRADERFSMCSTFKTYAAARILQLSN +AGAADLDTKMPIARDDIVVDSPITRDAVGSSMSLGDICAVAMMHSDNTAGNIMLRTIGGP +AAITAFARSIGDTHSRLDRWEPDLNTAIPADPRDTTTPKALCTGYRRILTADVLATPARD +RLLTWMKSNVTSSKRFRAGLPPGWTSADKTGAGDYGSTNDAGLLIGPNGQRVVAVVMTRS +RDHDAPPFNEAIAGAIRV----- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A127AX88_KLEPN +-----------------------DNTADNSQI-LXRADERFAMGSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARHLGDQTFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLPNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTLLH- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815) TaxID=391038 RepID=UPI000A2BFC0B +---ARERFEQLEASSGGRLGVAALRTADGSYV-GYRESERFPMCSTFKLLAVALILKRSM +AERGLLEERIRYGDAQVVAHSPVTKRHAGGEMTVGELSAAALQHSDNTAANLLLTSLGGP +EVLNQFALSIGDTWFDLVRNEPEVNASVPGDMRDTTSPRAMLLDVQKLLLDDVLGARERE +QLKAWMLGNTTGATRIRAAVPAGWLVADNTGSGDYGTANDVAVVYPPSSAPLVVAIYFTG +VTKETPPQDAIVDEAARIVFD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID8499 TaxID=2706106 RepID=A0A6B3EC10_9ACTN +--RAEAQLAALERRFGGRIGVYAVDTGTGAEV-RHRAGERFLMCSTHKLLTVAAVLRARW +DRPDLLDQVVAYRSSDVIAHSPATAPHVADGMTVAALCRAALTLSDNTAANLLLRTVGGP +AAVTRLVRALGDPATRLDRTEPHVNDA--DGVLDTTTPAHLAADLRALTLGHALEARDRD +RLLAWLDASTTGDRAVRAGCPRGWRIGDKTGSGSHGESNDVAVIRPPHRAPLVLTVFTAP +ADPRSTAGQPTIAEAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 852002-51152_SCH6134967 TaxID=1834096 RepID=A0A1A2DZA7_9MYCO +---IEDRLGEMERRQNALIGVFATNLGTGRTI-AHRAQDPFAMCSTFKTYAAARVLQKAE +RGELALTDRITIEPGDIVPNSPVTEAHVGQTMTLAQLCQAALQRSDNAAGNWLLRVIGGP +SGVTDFARSIGDERSRLDRWEIELNAAVPGDPRDTTTPEAVGNGYRAILTGNALAEPQRR +QLEDWMRANQT--SSVRPVLPPGWATADKTGSGDFASTNDVGIAFGPAGERLLLAIMTRT +AAPDVPNDRQLVGEVASVLV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) TaxID=482957 RepID=UPI000841E517 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARESGATSFRLDHWEPELNNAAPDDERDTSTPVEMVDTLQRLLLGNTLQEPQRT +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. HI2714 TaxID=2015359 RepID=A0A228QTQ5_9BURK +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARESGATSFRLDHWEPELNNAAPDDERDTSTPVEMVDTLQRLLLGNTLQEPQRT +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas putida TaxID=303 RepID=UPI00125FEA7E +-----QAAKEAERTLGARVGYAIHDTDNGRTW-QYRADERFPMASTVKVLVCSALLHQ-- +-GRVSLARTVPIQQHDILPYAPVTQGMVGEDVSASRLCAITLETSDNTAVNGVLKALGGP +ATVTAFLRSIGDQTTRADRSEPELNEGRPGDERDTTSPQAMQRTLEALVLGTALDKPAQA +QLTRWMESNKVSGTLLRKGLPSDWRIADRSGSGGFGSRGVVAVMWPPGRGPIVAAIYLTQ +TQATLEQQDAAIAAIGRSL---- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=A0A2S9NHU0_9BURK +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS +LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTAFARASGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRT +QLTEWMVGGARGATGIAAGVPPGWRIANKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinokineospora enzanensis TaxID=155975 RepID=UPI000378E193 +------ALVALEAELGGRLGVYAIDTGTGRSA-GHRADELFLSCSTHKPLVAANILHRAE +TESALLGQLIRYDRSRLLEYAPITGRHVDTGMTVADLCAAAVEVSDNTADNLLFDLVGGP +AGVTAFVRSLGDTITRLDRVEPDLNVAAPGDERDTTTPTRITRTLGKLLLADGLTQPGKD +RLIGWMVDSTTGKDLVRAALPTGWRTGDKSGSGAQGQVNNVAITWPPNGAPWLVAVFTAP +NDHDGDRTRPFVARAAKIAVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium album TaxID=417948 RepID=UPI00041416DA +---ADEQFSALEDRFDARLGVHAVDTGSGDTV-GWREDERFAYASTIKALAVGALLDS-- +KGVEVMQEEVAVEEADILEHAPVAETRVGQTMSLGEASEAALVVSDNTAANYVFDAIGGP +HALDGQLEAIGDEVTVVERDEPDLNEAAPGDDRDTTTPAAAAGSLREYLLEDALDAEERA +MLTDWMKSNQTGETLVQAGVPDTWQVADKSGGGHYGSRGDIAVVWPEEGEPIVIAVYSSR +EEQDADYDDRLIAQAAQVAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Superficieibacter electus TaxID=2022662 RepID=A0A2P5GT59_9ENTR +--AITNVLQQYETRLNARIGMAVVNEHGVPVF-SWRQDERFPLTSTFKVLACAALLDKLH +KSGGSLEQTVSIQPEKLLEYSPITKNHLSPALTLRTLCSAAVSYSDNTAANRLLEYLGGP +PAVTQFMRSIDDHVTRLDRTEPTLNEATPGDVRDTSTPKNMALALHQLLASDTLSQADRK +MLDTWMRDDKVADALLRATLPAGWAIADKTGAGGHGSRAIIAAVYPPEKPPFYLAIYITQ +TNMPMKAADAAIADIGRQLFN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-1521 TaxID=1609100 RepID=A0A0X3X5K2_9ACTN +---LTGHLRALEQEYAARLGVFALDTASGATV-SHRAGERFPMCSVFKGLAAGAVLRDVD +RHGEFLGRRIRYTAEFVEAYRPVTGKNIANGLTGAELCAAAVSESDNGAGNLLLRELGGP +TAITRFCRSLGDDTTRLDRWEPELNTAEPWRTEDTTSPRAIGMTYGRLLLGRALAARDRE +RLWDWLVANTTNTERFRKGLPADWILADKTGGGSYGVANDVGVVQPPGRSPLVLAVLSTK +LDPQGPTENPLVARAAALVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Kocuria koreensis TaxID=592378 RepID=UPI001011C881 +--DVVSELRELERQLDGEIGVHAIDTSTGECF-GYRDQQPFLLCSVSKVLVVATVLNRAS +HDPKLLGRRVDITQEDILAYAPVTSKHLEDGMTVEELCAAALTVSDNTASNLLMEQCGGP +EAVTDFVRSTGDLTTRLDRIEPDLNDA--SGGLDTTTPAAFSETLNRLTLGGALSASGRD +KLVGWMKESATGAEQIRAGLPEGTLVGDKTGSGTHGESNDVAVIWPKQGGPIIMSVFTTS +SRADTDGQKAAIAGTARAVF--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0008421FD9 +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVTAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIEWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A132DQK5_BURVI +----RSELAALDKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP +QAVTAFAHESGDTVFRLDRWEPELNRATPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA +QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ +AQADAAARADVVASAARIAT--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia testacea TaxID=248551 RepID=UPI000A0297C7 +--DLSNTLMTLQAKYNVLFGIAAVDTRGGRTF-EWNADDRFAMCSTFKVYAVAAILRLAE +RRELDLNDKVPITRQDIVMNSPVSYDHIGELMSYYELSRAALVRSDNTAANLLLRRLGGP +AAVTAFARSINDSQTRLDRWEPELNEARAGDSRDTSTASAFAAGYRKLILGDGLSTEYRR +MLTSWMRSSVTSRQRLRAGLPVGWVAADKTGSGAYGTANDAGVVWGPTGTSLVLVIFSRS +TTPMAAGADAAVADAAAAVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Achromobacter denitrificans TaxID=32002 RepID=UPI0009E775F4 +--TLSRELVRLETAGRGRLGVALLDTASGQAA-GHRGDERFLMLSSFKTLAAAYILARAD +RGEDQLTRRIPITEADLQEHAPVTRLHVGPQMTLAELCEATITTSDNTAANLMHRSYGGP +QALTRYIRSLGDTVTRHDRYEPELNRPHAGAPLDSTSPNAMNGTLNALLFGAALKPASQQ +LLRSWLLANTTGGKRLRAGFPPDWKVGEKTGTYSKVGANDAGYAQAPGGAPILVCAYLET +TAVPMPERDGIIAEVGRLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium tokaiense TaxID=39695 RepID=A0A378T8H7_9MYCO +----AERLAELERRHNAMVGLYAVDLQTGRTL-VHRENERFAVCSTFKAYLAARTLQAAA +RGEFAMTDTVTVRAEDLLPNSPVTETRVGHTITLAELCAAVLQVSDNAGANYLLHQIGGP +PAITEFARSIGDQETRLDRWETELNSAVPGDPRDTSTPTALGNGFRALITGDALEPQART +QLMDWMLANTT--SSLRPGLPADWTFADKTGSGDYGTTNDIGVAFGPDGRAVLLSVMLRS +ASPDAEGFRPVMPEIATLVLQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI0012613E15 +--ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD +AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP +AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDLRDTTTPNAINHTLNTLVLGETSSSASRQ +QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ +TEATFDERNAAIVTIGKSIFDTf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. BK042 TaxID=2512137 RepID=UPI00104C95EA +---APKGLRELEARHGARLGVFARNIVTGRTV-RYRAGELFPMCSLFKTLASAAVLRDLD +RDGEFLSRRIHYTDADLPKGSDKTREHLADGMTVAELAEVAITFSDNGAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWETELNSAEPWRITDTTSPYAIGRTYGRLVLGDALDGPDHA +LLTHWLRNNTTSGTRLRAGLPPAWTVADKTGGGSYGTNNNVGIAWTEDGTPLLLAVLSTL +PAQDAARDDVLIRDTAALLA--- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=unclassified Mesorhizobium TaxID=325217 RepID=A0A435F1K7_9RHIZ +-----------------------------------RENELFPMCSTFKTLAAALILHRVD +GGIEQLERSIKIPHNAIIANSPTTKKFAGGEMTVAQLCEAAVTVSDNGAANLLLESFGGP +PQLTAYLRSIGDSVSRLDRIEPELNESLPGDERDTTSPLAMVEDYERLALGNSLSDKSRA +QLVEWLVANKTGDERIRAGLPKGWRCGDKTGTGDRGSTNDAAVIWPASGNPILMSVYLTG +TKQSLTKRNAVIASVSRTLVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_035 TaxID=2175673 RepID=UPI000DA72DA6 +----APAFDRLQQTYGATLGVFALDTGTRQTV-AHNANRRFAYASTYKSLAAGVLLADPS +---TDLDAHVDLAQDEILAGSPVTSQHVESGMRLGDVVAAALEQSDNTAGNIVLQRVGGP +AGFETALRRIGDTTTRSDRTEPDLNAAVPGDDRDTSTPRALALDLDRLVLGSVLHASERA +RLIGWMRANTTGDDLVRAAVPAGWTVADKTGTGYYGVRNDIAVVWPPSGAPIVLAIQTTK +STQAAEPSDALVAAAAKEAI--- +>[subseq from] Beta-lactamase Toho-1 n=1 Tax=Legionella hackeliae TaxID=449 RepID=A0A0A8UTF0_LEGHA +---LKKKLAELEASSGGRIGVYAINTANNAHL-QYRANERFPTGCTSKVMGVATILNQSM +NDSSLLSQKISYTKNDLTNWNPITEKHLATGMTVAELCAASISYSDNTAMNLLVKKMGGV +EQMNVFARSINDTSFRQDNWPKEALSGGKGNLKDSSTPKAMAKSLQKLAFTNVLAEPQRQ +QLLSWLKATTTGDFRIRAGVPKGWVVGDKTGTGSYGTTNDIGIIWPPKCAPIVVAVYYTS +DDKKAVKREDVVASATRLLIDKf +>[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. 10N.261.52.A1 TaxID=1880849 RepID=A0A2N7HDS8_9VIBR +-----ESIEQIESRVSARIGVAVYDSATKKAW-SYKGDERFPMMSTFKTLACANLLYDAE +NKGLDLDSQVNIKSEDLIVWSPVTKELVDKGISLRDACSATMTMSDNTAANIVLGGIDGP +NGLTQFLRSIGDSNTRLDHLEPELNHARPDDARDTTTPKSIVMTLNKLMYGDTLSQASKS +TLKGWMMGNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWSEHRAPLIISVALTE +TEFTLQQRDKVINEVGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas fluorescens TaxID=294 RepID=UPI00130DA964 +-----------------------MDVASGAQW-SYRGDQRFPMASTFKAFTCASLLSQVD +RGRLDLSQRIAFTQDELDSYSPVTRDHVGGQLSLLQLCDAATSMSDNTATNLVLKTVGGP +AGLTAFMRSIGDNSTRIDRYEPELSDVPPGDPRDTTTPNAAAKSLQALLLGDVLSDASRQ +QLETWLVDNKVSAALLRASLPEGWKIADRTGAAEYGSRGIIAVIWPETHGPVVVAAYLSG +TRLSLEERDTVLAEVGAALV--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium tusciae TaxID=75922 RepID=UPI00047F95B6 +--SVDASIQGLEQQHNALIGIFATNLVSGKTV-AHRAQDPFAMCSTFKGYASARVLQMAQ +HRELSLDDKMFVDPASILPNSPVTEPRAGGEMTLAELCQAALQQSDNAAANILLNRIGGP +QSITAFARSIGDERSRLDRWETELNAAIPGDLRDTSTPEALGGGYRALLDGDVLAPAGRR +LLEDWMRANQT--SSMRAGLPPGWTTADKTGSGDYGSTNDVGIAYGPDGQRVVLAILTRS +QANDAENMRPLIGEITALVM--- +>[subseq from] Beta-lactamase class A n=1 Tax=Mycolicibacterium litorale TaxID=758802 RepID=A0A4R8J447_9MYCO +----DADLIALEDRHGAHIGLWAVDLISGRTL-GHRADERLAMCSTFKTYAVGRVLQLAA +GGALDLDTAVPIDAADIVVDSPVTSTRIGSSMSLAELCDAALTRSDNTAGNALLRRIGGP +EAVTTFARAVGDEETRLDRWEPDLNEALPGDPRDTTTPRALNSGYRRLLVDDALDSRSRE +RLVSWMRGNVTSGKRFRAGLPAGWTSADKTGAGGFGTTNDAGLLIGPSGQRVLLAVLTRS +SARDSDPLNAAIADTVA------ +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI0006A7867D +-sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNTILNTLRTLVEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLVAQISQLILQKy +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis (strain G4 / LMG 22486) TaxID=269482 RepID=UPI000766E14B +----RSELAALDKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP +QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA +QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ +AQADAAARADVVASAARIAT--- +>[subseq from] Beta-lactamase n=1 Tax=Lichenibacterium ramalinae TaxID=2316527 RepID=A0A4Q2RFN3_9RHIZ +--AAEDALAALEARHGGRLGVFALDTGTGRSL-AHRADERFLMCSTTKFASVAALLARVD +AGTERRDRRVAYGAADVAVYAPDTKAHLAEGMDVEALCRAAMVHSDNGAANLVLASLGGP +DAVTRFVRGLGDGVTRFDRTEPTLNRT--DGPLDTTTPRAFAGTLRAVLLGEALAPASRS +LLEGWMVACETGRARIRAGVPAGWTVGDKTGTAGP-NAGDVALLRPPGRAPIVVAAYCDA +PKLADAEREAVLKAVGTAV---- +>[subseq from] Beta-lactamase n=2 Tax=Mycobacterium triplex TaxID=47839 RepID=A0A024JWE5_9MYCO +--QVYDRLAELERQYNAYIGLFATDLGSGRAL-AHRDDDPFAMCSTFKAYAAARVLQKVQ +RGELDLQQGVFIDPAALLPNSPVTAPRAGATLPLAQLCAAAVQRSDNVAANLVLAQIGGP +PAITDFARSIGDERTRLDRWEIELNTAIPGDPRDTSTPRALGSGIQSLLTGTVLADPQRR +QLEDWMRGNVT--STMRAGLPPGWTIADKTGTGDYGSTNDVGMVYGPTGQRVLLSLMTRS +QAPDAQALRPLIAEVTKSVL--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium marinum (strain ATCC BAA-535 / M) TaxID=216594 RepID=B2HFS3_MYCMM +--DLESRFAELEQKYEARLGVYVPGTDATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP +--IAHLGTVITYNSADIRSTSPITEQHLATGMSIGGLCDATIRYSDGTAANLLLQDIGGI +AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALLPEKRD +KLIDWLGRSTTGAKRIRAGFPADWRVIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR +VGPEAPWCDPLVADAAKCVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Actinokineospora mzabensis TaxID=1470177 RepID=A0A317S159_9PSEU +----AEELVALESTFGGRLGVYAVDTADGTEV-RHRADERFLMCSTAKVPVSAAVLRRRL +AEPGLLERVIRYTEADLLEYAPVTSEHVAEGMAVADLCVAALTRSDNTAVNLLLPLVGGP +AGVTDFVGTLGDRTTRFDRPEPDLNVTAPGDERDTSTPLALSSTVRALVVDDGLDRPGRE +LLAGWMRASVTGKDLIRAGVPAGWDVADKSGSGAQGEVNNVAVVWPPNRAPWVITVFTSP +TDPKTTRGRTTVAAAAGIVAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000B914406 +-----RAVQEVEQSLQARVGLAVLDTADGQWW-QYRADERFPMASTSKALICAALLARGP +---GAMKTAWLIKEEAIQSYAPTTKELIGQQVSAAQLCAITMRNSDNSAANGVLEVLGGP +EAITSFLRGVGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLRNLVLGDALKASDRD +RLIDWLRHNEVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVMWPPERGPLVAAVYITE +TKASMEARNAAIATIGKAMA--- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Methylobacterium TaxID=2615210 RepID=A0A5C8T6X4_9RHIZ +--AAAARIVAVEARLGGRVGVAFRD-ASGVFL-GHRAGEAFAMCSTFKVLAAAAILARAA +AGAETLDRRIAYAAADLQSYGPVTRAALANALTVEALCAAAIVWSDNTAANLLLDALGGP +AALTAWLRGQGDAVTRLDRTEPTLNTALPGDPRDTTSPSAITGTLERCLLGDVLTPPHRA +RLEGWMVACETGRTKLRAGLPLDWTVGDKTGSGDNATSNVVAILHPPGRPPILAGLFLTG +SEAPPATRDAAHAEIGRILVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A345N7N7_VIBPH +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLVRSALPAGWFIADKSG----------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium elephantis TaxID=81858 RepID=UPI0007EA4D3A +--AVEAQIAALEIQHGALIGVYASNLDLQRTV-AHRAQERFAMCSTFKTYAAARTLQMAE +RGELSLEQSLFVDPEDILINSPITEARAGGELTLAELCQAALQRSDNTAANMLLATLGGP +QAITAFARSIGDSESRLDRWETALNSAIPGDPRDTSTPQALGFGYRNLLAGDALAPPQRS +RLEDWMRANQT--SSMRAGLPDGWTSADKTGGGDYGSTNDVGIAYGPDGQRVLLALMTRS +QTADAPGLRPLIGELTSLV---- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium litorale TaxID=758802 RepID=UPI001065ECF4 +----DADLIALEDRHGAHIGLWAVDLISGRTL-GHRADERLAMCSTFKTYAVGRVLQLAA +GGALDLDTAVPIDAADIVVDSPVTSTRIGSSMSLAELCDAALTRSDNTAGNALLRRIGGP +EAVTTFARAVGDEETRLDRWEPDLNEALPGDPRDTTTPRALNSGYRRLLVDDALDSRSRE +RLVSWMRGNVTSGKRFRAGLPAGWTSADKTGAGGFGTTNDAGLLIGPSGQRVLLAVLTRS +SARDSDPLNAAIADTVA------ +>[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea candida TaxID=359159 RepID=UPI0005BA7D93 +--RVKKELRALERAFNGRIGAYAFDAASGRTV-SYRAGERFPMLSTFKAPLCAAVLHKAR +TSPGLMSKVIRWTAADMTPNSPVTEKHLKDGLTVSRLCEAAVTRSDGTASNLLLRQIGGP +AGLTAYFRTLKDPLSRMDRWHPELNDWTPKDKRDTTTPAAIARDLRLLTTGTALHAKDRE +QLLAWLLRSEVGAERIPAGLPKSWTVAHKTGTNSFGGGNDVAVIWPAKGAPIVMAVYTNR +TP-GLPTDNQTIAKTATVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI0011105F7E +---LEQRVQYF-EDKGWSIGVTVLDTESGNIN-SVNGDKRFHFNSTIKALACANVLSKVD +KNKISLDDSISLKKSDIVTYSPVTEDYIGKKLTLRKACEAALTYSDNTAANYTISAGGGP +EGLTKFMRSIGDDVLRSDRYEPELTKNIEYDIRDTTTTNAMASSLNKLLLENVLSEESKL +QLKKWMKGNKVANDLLRASLPQGWSIADRSGASDYGVRGIISMAWSKDHEPVIITMYVRK +SNTTMKERDQVIADIGKVIFEQy +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) TaxID=482957 RepID=Q397K2_BURL3 +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGATSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRA +QLTEWMVGGARGATGIAAGVPSGWRIADKAGTGGYGTTTDIAVLWPPSRAPIVLAVSFTQ +PQAGAAARADVVASAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia caribensis TaxID=75105 RepID=A0A2T3Y4F3_9BURK +---ARERFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM +AERGLLDERVRYGDADLVANSPVTKRRVGEGMAIGELSAAALQHSDNTAANLLLTAVGGP +EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE +LLKAWMLGNVTGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG +VMKETLPRDEVVVEAARIVFD-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium rhodesiae JS60 TaxID=931627 RepID=G4I8K6_MYCRH +---LEQRIAALEKRHNASVGLYAQDLDSTATV-AHRDGDRFAMCSTFKAYLAARVLQKAQ +AGELQLTDTALVDPDLLRTNSPRTEPNVGKQMALSDLCAAALQVSDNTAANVLLRVIGGP +PAITAFARSIGDDRSRLDRWETELNSALPGDPRDTSTPRALGGGIVAVLTGGVLDAPHRQ +QLEDWMRANTT--SSMRAGLPPGWTTADKTGSGDYASTNDVGIAFGPNGERLLLAIMTRT +RSANAPALRDLIAEVATLVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI000D06D17F +--ALVDIIKQQEKALNGTIGMAVLYTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KDKSVLTHSVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ +SSASMDERNKAIATIGKQVFTYf +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum frisingense TaxID=92645 RepID=UPI00028C1642 +---ATSPLAELEHRYGGRLGVFAVDTGSGKTL-AHRADERFLMCSTFKGMLAAQVLARVD +QGKESLQRSIPYTRKDLIFTSPTTLTNVGRGMTVGELCQATLELSDNTAAILLMRNAGGP +DGLTAFLRSLGDTVTRSDRYEPMSNQY--SGERDTTTPRAIVGNARAILTGDVLSPDARQ +QLEDWMIACRPGRNRLRAALPADWQAGDRPGTSVERQTNDYAIVRPPQRNPLFVAAYYDA +PTLDMPRREAALREVGEIFV--- +>[subseq from] Beta-lactamase n=3 Tax=Atlantibacter hermannii TaxID=565 RepID=H5V4T3_ATLHE +---MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ +KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP +DAVTQFMRGIGDHVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTSPPLISANRA +TLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ +TEASMKMANETIAEIGKQLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFE482A +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRAAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SEQ1_9BACT +--TLSKAVQAEEARLGARIGMAVFDAKDRTRW-AHRGDERFPLNSTHKSFSCAALLKQVD +RRVLALENVISIERASLVTYSPVMEKT-GGQVTLREACAASVSWSDNTAANIVTDAIGGP +QAFTVFMRDIGDQHTRLDRKEPEMNEATPNDLRDTTTPNAIVESLRRIILGDVLREDSRA +LLTDWMINDKVADALLRATLPRTWSIADKSGAGGHGSRSIVAVIWPKDRDPVVVGIYITQ +TSAPMADSNAAIARLGSVLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. BH-1 TaxID=2058884 RepID=A0A2N6J8J9_9BURK +---ATSPLAELEQHYGGRLGVFAVDTGSGKTL-AHRADERFLMCSTFKGMLAAQVLARVD +QGKESLQRSIPYTRKDLIFTSPTTLTNVGRGMTVGELCQATVELSDNTAAILLMRNAGGP +EGLTAFLRSLGDTVTRSDRYEPMSNQY--SGERDTTTPRAIVGNARAILTGDVLSPDARQ +QLEDWMIACRPGRNRLRAALPADWQAGDRPGTSVERQTNDYAIVRPPQRNPLFVAAYYDA +PTLDMPRREAALREVGDIFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0013F44375 +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAGARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D00DF53 +--RAQAELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNAVGPGDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGAAAAVPPGWRVAAKRGGGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A658D4N1_9BURK +--SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRVDAAPRSDVIASAARIAAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9099 TaxID=2184568 RepID=UPI000F5EBE44 +---AQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTALLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTAFRLDRWEPELNQAAPGDERDTSTPVAMVDMLQRLLLGDTLREPQRA +QLTEWMTGGAT---GIAAGVPPGWRSAGKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio bivalvicida TaxID=1276888 RepID=UPI001428D338 +--AVEKAIERQEETLSARIGVAVLNVETGALW-SFRGDERFPLTSTFKSIACAKLLYDAD +QKTTELKKTVTVNREGLVAYSPVLEAYIDKEITLGDACQATMLTSDNTAANIVIASVGGT +DSITSFVRELGDENTRLDRVEPELNEALPNDPRDTTTPISMTNTLNELVFGAVLSENSRA +QLIDWMKRNEVTGNLLRSVLPVGWEIADRSGAGGFGARSINAVVWLDKKSPIIVSIYVIQ +TDASMDQRNLAIVEIGKSIFDLf +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010F7ADCF +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTV----------------------------- +----------------------- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio TaxID=662 RepID=UPI000312F63D +-sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD +SSKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNAILNTLRTLVEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLVAQISQLILQKy +>[subseq from] Beta-lactamase n=1 Tax=Legionella maceachernii TaxID=466 RepID=A0A0W0WCW3_9GAMM +--SINQKLSQLESSSGGRIGVYAINTANNTHL-GYRATERFPMACTSKVMGVAAVLKKSM +KDKSLLAQKITYTKSDLTNWAPITEKNLNTGMSVKALCAAAISYSDNTAMNLLLKQLGGV +KGMNAFARTIHDDMFQQTHWPGEAMSGGQHNSDDSSTPAAMANSLKRLAFTDVLAKPQRE +LLLTWLRANTTGNSRIRAGVPQGWLVGDKTGSGYYGTTNDIAIIWPPKCAPIVMAVYYTS +NNKEAPKRGDIVASATRIILDEf +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobiaceae bacterium TaxID=2072420 RepID=A0A4Q5PYE4_9BRAD +-------LLAYERDSGGRIGLYARNITSGAEI-AWRADERFVMCSTFKASLAACMLARVD +RGEDRLDAMVAYTEKDLLDYAPVAKEHLAKNLSVGEMARAIVELSDNTCANLLLARAGGP +AALTRFWRDHGDSISRLDHDEPELNRTPPGGLDDTTTPRAMATSLQRLALGDALQPRSRA +QLIEWMVNCKTGANRLRAGLPTTWTIGDKTGNNGSDAAGDIAVVWPSADRPVVIAAYTRG +GRPTPAQLNTVFKAIGELA---- +>[subseq from] Beta-lactamase n=1 Tax=Hyphomonadaceae bacterium TaxID=2026748 RepID=A0A3D3Z4A8_9RHOB +---PTAELAALEAKSQGRLGVGILDIASGELV-GHRQDERFALCSTFKLPLAAEVLRDVD +AGKRTLDQFIPYSKADMVAHAPVTEANLAAGMAIGELAKATQITSDNPAANLILREFGGP +EAMTQRIRAAGDPVTRIDRYEPMMNRVVGDDPRDTTSPAAMARLVARYLTTDYLSQASRD +LLIGWMIETQTGTKRLRAGLPVDWKAGDKTGTAMTDRYNDVAIVWPPGRAPLIIAAYFNT +NIDMRDEFQAVLAEAGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075AA0B2 +----RSELAALDKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP +QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA +QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ +AQADAAARADVVASAARIAT--- +>[subseq from] Beta-lactamase class C n=3 Tax=Burkholderia TaxID=32008 RepID=A0A132D7S0_BURVI +----RSELAALDKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP +QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA +QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ +AQADAAARADVVASAARIAT--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio bivalvicida TaxID=1276888 RepID=A0A177Y2S2_9VIBR +--AVEKAIERQEETLSARIGVAVLNVETGALW-SFRGDERFPLTSTFKSIACAKLLYDAD +QKTTELKKTVTVNREGLVAYSPVLEAYIDKEITLGDACQATMLTSDNTAANIVIASVGGT +DSITSFVRELGDENTRLDRVEPELNEALPNDPRDTTTPISMTNTLNELVFGAVLSENSRA +QLIDWMKRNEVTGNLLRSVLPVGWEIADRSGAGGFGARSINAVVWLDKKSPIIVSIYVIQ +TDASMDQRNLAIVEIGKSIFDLf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis sp. (strain 113P3) TaxID=292913 RepID=UPI0009FA9805 +----AGRLAALEREAGGRLGVLFLDSANGRSA-GHRSDERFALCSTVKWPLAAVVLDAVD +AGGLSLDQRIRFDKSDLLSNSPRTRENLARGMSVAELLEAAITVSDNAAANLLLPLVGGP +EGVTRQFRAWGDAVTRLDRREPMLNRVGEGEVRDTTTPAAMAALLRTLLLGDALSDASRK +RLIDWGAATTTGPRRLRAGLPASWVLAHKTGTAMMNKYNDIAIAYPPRGAPLLIAAYYEG +PVAVRGEDEAVLAAVGKLAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia caribensis TaxID=75105 RepID=UPI0007226839 +---ARERFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM +AERGLLDERVRYGDADLVANSPVTKRRVGEGMTIGELSAAALQHSDNTAANLLLTAVGGP +EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRA +LLKAWMLGNVTGAARIRAAVSSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG +VMKETLPRDEVVVEAARIVFD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X7Z9_9BACT +--------ENIEERLDARVGLLIRDSGTGWSW-GHRADERFLMNSTAKVPLCGAVLAQVD +KGAMRLTDGLDVRAEDMVEYAPVTELRIGDTMQVGELCFAALDMSDNAAANSLIDHLGGP +QEVTAFMRQIGDDVSRLDRREPDLNRFETGDPRDTTSPAAAVDTLERLLVGDALSPSSRA +QLTEWMTPGGVTGALLRAFTPDSWRVADKSGSGSV-TRNIVGMIAPPQGGPYFVAIYLSE +AEADFDTRNAAVVAISAAVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Streptomyces philanthi TaxID=371608 RepID=A0A367FCY6_9ACTN +----AAAFKKLEAEYGARLGVHALDTGSGRAV-SYHADERFAYASTHKAFTAAAVLDTYS +LKGL-DDKSLTVGKDVPVGHSPVTSAHVGEQLTLRELCEAAVRQSDNGADNLLVRDLGGP +EKLDAYLEGLGDDVTQMNRYETALTEATPGDKRDTTTPRAFAEDLRAVTVGDALHEPERA +QLDDWLDESPTGTELIRAGVPKEWSVGDKSGAARYGTRNDIAVVRPPGKAPLIVTVMSKR +KKEDADYDDKLVAEAASVVADK- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. GY16 TaxID=2653200 RepID=A0A5P8KJC7_9ACTN +---LSPRLAELEREHAARVGVFAHDTATGRTV-AYRADELFPICSVFKTLGAAVVLRDLD +RDGEYLAKRIHYTKEYVEAYCPVTSRNVEAGMTVAELCAASVSHSDNGAANLLLREVGGP +TAITRFSRSLGDRTTRLDRWEPALNSAEPWRKTDTTTPRAIGGTYARLLLGRALPDADRE +LLTGWLIANSTNVERFLAGLPADWTLADKTGGGSYGVANDVGVVWPPHRPPLVLSVLTTK +HAPEGPSDNPLVAEVAGLIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. (strain 113P3) TaxID=292913 RepID=A0A0M4CNK1_SPHS1 +----AGRLAALEREAGGRLGVLFLDSANGRSA-GHRSDERFALCSTVKWPLAAVVLDAVD +AGGLSLDQRIRFDKSDLLSNSPRTRENLARGMSVAELLEAAITVSDNAAANLLLPLVGGP +EGVTRQFRAWGDAVTRLDRREPMLNRVGEGEVRDTTTPAAMAALLRTLLLGDALSDASRK +RLIDWGAATTTGPRRLRAGLPASWVLAHKTGTAMMNKYNDIAIAYPPRGAPLLIAAYYEG +PVAVRGEDEAVLAAVGKLAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. VT-16-41 TaxID=1953765 RepID=A0A1V2VI74_9BURK +---ATSPLAELEHRYGGRLGVFAVDTGSGKTL-AHRADERFLMCSTFKGMLAAQVLARVD +QGKESLQRSIPYTRKDLIFTSPTTLTNVGRGMTVGELCQATVELSDNTAAILLMRNAGGP +EGLTAFLRSLGDTVTRSDRYEPMSNQY--SGARDTTTPRAIVGNARAILTGDVLSPDARQ +QLEDWMIACRPGRNRLRAALPADWQAGDRPGTSVERQTNDYAIVRPPQRNPLFVAAYYDA +PTLDMPRREAALREVGEIFV--- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces melanosporofaciens TaxID=67327 RepID=A0A1H4IA45_STRMJ +---LAQRLRALETEHGARLGVFALDTATGRTV-TYRAGERFPICSVFKALAAAAVLRDLD +HGGDVLARRIRYDAALVRRYSPVTSRNLAEGMTVSELCAAAVSESDNTAGNLLLRLLNGP +TGITRFCRSLGDGTTRLDRWEPELNSAEPWRKTDTTSPAALGGTFGRLLLGDALCLEDRR +LLTDWLVANTTNGERFRKALPTDWVLADKTGGGDYGVANDVGVVWPPKRQPLLLSLLSTT +HDPAGPSDDLLVAEATRMVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura roseirufa TaxID=2094049 RepID=UPI001041342C +----GRRLRALEKARGTRIGAYAIDTGTGRFL-GYRADERFAFLSTFKAMASAAVLRKAR +RDPGLMDRVVHYTEADLVEHSPVTKEHVATGMTVAELCDAAITVSDNTAGNLVLRQIGGP +AGHTAFLRSLGDRISRADRWETDLNIWAPGERRDTTAPRVWARDLRDLAVGPALDPADRA +RLTGWLKDSETGAARIRAGLPKDWTVGDKTGTNDAGLANDVAVAWPPSGAPLVFVVLTNR +RSGG-GADDGAVARTATI----- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. AU33423 TaxID=2015355 RepID=UPI000B7A57BD +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARESGATSFRLDHWEPELNNAAPDDERDTSTPVEMVDTLQRLLLGNTLQEPQRT +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPARAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Serine hydrolase n=2 Tax=Georgenia sp. Z294 TaxID=2585135 RepID=A0A5B8ASV5_9MICO +------------AAAGVTLSVAVTGLADGASL-VAGTDERVKAASIIKLPLLATLMADVD +AGDLDLAEVVTIPAGDIVGGSGTLQDRSFPLITVGELMELMVQVSDNTATNVLIDLAGGF +DAVNEYTADLGLEDLRLGRKMI--HPASPPLQENYISAAEVTELVTLLWDGGILSESSSE +YVLDLMRGQLV-DTKFGAVVP-RAHLANKTGELSD-VSHDSGVILLPGRE-LALTATSSF +TGMPREEADVFVQEAARVVYD-- +>[subseq from] Serine hydrolase n=2 Tax=Georgenia sp. Z294 TaxID=2585135 RepID=A0A5B8ASV5_9MICO +---------------GIRASVGFTDLADGGAL-LLGSPAPYNPASVIKLSLLATVMRQAE +RGMLNLDAPVTISPYMVVAGSGSLQHEQMPYTTVRELTRLMVVQSDNTATNVLLYYT-GI +PTTRELLDDLGLEVMRFNRQMFPGDR--ISDPANVLDLADTMGLLEAMYGDDLLAAGSRD +QILTWMGDQEV-DTKFGAVLD-DAPVAHKTGETGN-VTHDVGYFLVPGHE-AAVAVLTEV +TTEAQEIGNPVVQEIGLAIYEY- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-384 TaxID=1463905 RepID=UPI0004C4A2DD +--RLADSLRELEREHGARLGVLAHDTGSGTTV-RYRADEAFPLCSTFKPLAVAALMRAGD +----DLSARVHYTDADVADYAPVTGR--TRVLTVAELCAAAVEFSDNTAANLLLRRLGGP +TAVTRFCRSLGDPATRLDRWEPALNSAEPDRTTDTTTPHALARTFARLTLGDALTRPHRA +RLTAWLRASTTGAHRLRAGLPPSWALADKTGTGSYGTANDLALAWPPHRPPLVLAVLSTK +PTPTAAPDEPLLARTAALLA--- +>[subseq from] Beta-lactamase n=2 Tax=Moritella marina TaxID=90736 RepID=Q9RA17_MORMI +--TLNNSISAIEQRISGRIGVAVLDTQNKQTW-AYNGDAHFPMMSTFKTLACAKMLSEST +NGNLDPSTSSLIKAEELIPWSPVTKTFVNNTITVAKACEATMLTSDNTAANIVLQYIGGP +QGVTAFLREIGDEESQLDRIEPELNEAKVGDLRDTTTPKAIVTTLNKLLLGDVLLDLDKN +QLKTWMQNNKVSDPLLRSILPQGWFIADRSGAGGNGSRGITAMLWHSERQPLIISIYLTE +TELAMAMRNEIIVEIGKLIFKEy +>[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides immunogenum TaxID=83262 RepID=A0A179V839_9MYCO +---KSTELASLENDFGGRLGVHALDTGSGDTL-SHRANERFIMCSTVKTFIVSAILHRRL +SEPGLLDKRIQYTQADIMEWAPIASQHVAEGMTVSELCDATIRYSDNTGANLLIAELGGP +KETEKYVRSLGDNVSRMDRLEEQLN--IPDGDLDTSTPLQLATNLRRLALDEGLDAQGRE +LLTGWLKRNTTGDQSVRAGVPAGWTVGDKTGGGFKGETNDIAVIWPPGRAPIVVAVLAIP +DDPKSTKGKPTIAAATRIALKAf +>[subseq from] Beta-lactamase n=4 Tax=Vibrionaceae TaxID=641 RepID=H1A9J3_PHODD +--TLNDSLYSIEQRTLGRIGVSVLD-STDQQW-HYKGNERFPMMSTFKTLACAKMLQDSD +RDILDISTMAPVKSDELIAWSPITKNMVGSSITIENACEATMKTSDNTAANIVLKHIGGP +QGVTAFLRLIGDKVTQLDRFEPELNQAKADDLRDTTTPNAMNKTLYHILFEDVLAQNSKK +QLKEWMQGNTVSDSLLRSVLPKGWSIADRSGAGANGSRGITAAIWTDEREPLIISIYLTQ +TNLSMPERNQVINEIGKAIFEEy +>[subseq from] Beta-lactamase n=2 Tax=Lechevalieria deserti TaxID=531939 RepID=A0A316I4L2_9PSEU +-----DALVELEKKYDARLGVYAAGVG---TI-EHRADERFAFCSTFKGLAAAAVLHRNP +--MTHLDKVVTYTEADLMKSSAITKRHVQTGMKLRDLCDAAVRFSDGTAGNLLLRELGGP +AELTKYLRELGDDVTRMDRIEPAITEATPGDPRDTATPRSLGTDYQRLVLGNTLDQEKRG +FLTDLLERSVTGAKRIRAGVPQGSRVASKTGTGDYGTANDIAVVWQPSREPILIAIMSSR +STADARYDEALIAEAAAYVTK-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. N23 TaxID=1987376 RepID=A0A292YNH1_9PSEU +-------VDALERRYTRRIGVHAVETRTGAAV-AHRGTERFLMCSTVKALMAAFVLHMST +TDPGLLDRRVRVTRADVLAYAPITGTHVGSGMTVAELCRAAVTVSDNTAYNLLLRQTGGP +GALTAFVRGLGDDVTRADRTETTLNT--PDGELDTTTPAAMATTLRTLATTPALTPAARD +RWLAWMRANTTGDAQIRAGVPAGWSVADKTGSGDGGTKNDVGILVPPSAAPIVLTVFTVP +EHPDDGLGEQAVAATTRAAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. YC-RL4 TaxID=1682113 RepID=A0A172UQQ9_9MYCO +--TLEERIRELEARHNAFIGLYAANLQSGLVV-DNRADEPFALCSTFKTYAAARVLRGVA +DGEFSLDQPIFVPPEGVLPNSPVTGERLGQQMTLAELSQAALQRSDNLAANLLLEAIGGP +QAITAFARSIGDDRTRLDRWEIELNSAIPGDPRDTTTPRALATGYRNLLAGEALPPAQRE +LLEGWMRANQT--SSMRAGLPPGWTTADKTGSGDYATTNDSGVAYGPDGARVLLTIMTRT +QSADAEGLRPLIGEVAALVVP-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A3P0X4Q7_BURCE +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA +QLTEWLVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Enterovibrio norvegicus TaxID=188144 RepID=UPI0004749468 +----EKVIKMQEETLSARIGVAVLNVESGALY-SFRGDERFPLTSTFKSIACAKLLYDVD +QKRTELNNTVAVNSDDLVTYSPILEAYVEKEITLGDSCQATMLTSDNTAANIVIESVGGT +ESITSFLRDIGDVNTRLDRVEPELNEALPGDPRDTTTPISMTNTLNKLLFGTVLSQDSRV +QLIDWMKRNEVTGNLLRSALPSGWEIGDRSGAGGFGARSITAVVWRDKQSPLIVSIYVSQ +TDASMDQRNLAIVEIGKSIFDLf +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. DL99 TaxID=2528957 RepID=UPI001081F682 +---VDDQIAELERRDNVLIGLYAANLASGRTL-THRHDEMFAICSTFKGYAAGRVLQMVG +RRQISLDNRVFVDPEAIVPNSPVTETYAGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP +AGITAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAIGYRAMLAGDALNPPQRR +QLEDWMRANQT--SSMRAGLPDSWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS +QADDADNLRPLIGELTALV---- +>[subseq from] Beta-lactamase n=1 Tax=Atlantibacter hermannii TaxID=565 RepID=Q84EY3_ATLHE +---MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ +KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP +DAVTQFMRGIGEHVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTAPPLTPANRA +TLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ +TEASMKMANETIAEIGKQLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNT360 TaxID=1288080 RepID=UPI0003FE654B +-----AGFKKLESTYGARLGVYALDTGTGRKV-SYHADERFAYASTHKAFTAAAVLHKYS +--LNGLGKQITVGKDVPVGHSPVTSTHVGEKMTLRELCAAAVRQSDNGADNLLVRDLGGP +KKLDAYLAGLGDDVTQMNRYETALTEAAPGDPRDTTTPRAFTEDLRTVALADALDRPERS +LLGDWLRDNPFGTTLIKAGMPDRWRVGDKSGAARYGTRNDIAVVRPPGRAPLVVTVMSKR +AKEDADYDDALVAEAASVVADQ- +>[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobiaceae bacterium PARB1 TaxID=2015576 RepID=A0A257KLH9_9BRAD +-------LPAYERDSGGRIGLYAKNLTSGAEL-AWRAHDRFVMCSTFKASLAACVLARVD +RGQDRLDATVPYTQKDLLAYAPVAKENLSKGLSVGEMAKAIVELSDNTCANLLLARVGGP +QALTKFWRDHGDSISRLDHDEPELNRTPLGKLEDTTTPRAMATTLQRFVLGDALQAGSRA +QLTEWMVNCKTGANRLRAGLPTSWKIGDKTGNNGKDAAGDIAVVWPAPDRPVIIAAYTRG +GNPTSTQLNTVFKAIGGMV---- +>[subseq from] Class A beta-lactamase n=1 Tax=Rubrivivax sp. TaxID=50259 RepID=A0A519IGG0_9BURK +-------LVELERRSGGRLGVAMLDTGNGSLA-GHRLDERFGLCSMFKLPLAAVILSEAD +QGRLALDRRVHYVAADVHGHAPVTTKHLARGMTVAELAEAAQVTSDNPAANLLLKLIGGP +AGLTARLREFGDMTTRLDRMEPEMNHVPPGEVRDTTTPAAMARLVQKIALGDVLERPTRE +CLVGWMEKTQTGLHRLRAGLPSAWRVGDKTGTYTNGRVNDVAVCWPPGRAPLIVAATYRT +PRRGRDEDEAVLAEVGRIAA--- +>[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI00124EE2FF +-sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD +SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNTVLNTLRTLVEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLVAQISQLILQKy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Mycobacterium sp. ITM-2016-00317 TaxID=2099694 RepID=A0A2S8M8V4_9MYCO +-----ERLQALAQRHDAEIGVYAVDLVTQHNL-AFRADETFAVCSTIKTYIAAAVLQRTQ +TGQLSLQDTVPIEPDDIRPHSPVTEPRVGTSMTLAELCQAALQQSDNAAANGLLGVLGGP +PAVTAFARSIGDDRTRLDRWEVELNSAVPGDPRDTSTPRALGLGYREILTGDVLEPTVRQ +QLLDWMRANQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVVYGPAGQQVLLSLMTKS +ASGD------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI0009BE8C32 +--ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KDKSVLTHSVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRFVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ +SSVSMDERNKAIATIGKQVFTYf +>[subseq from] Beta-lactamase n=1 Tax=Lentzea flaviverrucosa TaxID=200379 RepID=A0A1H9JUG8_9PSEU +------ALFELEKKFDARLGVYAMS-DNGSTI-EHRADERFAFCSTFKGLAAAAVLHRNP +--MSHLDTVVTYTEADLMKSSVITKLNVRTGMKLRDVCDAAVRHSDGTAGNLLLRDLGGP +AELTKYLRELGDTETRMDRVEPGITSATPGDPRDTATPRSLGTDYQRIVLGDALEPAKRD +FLTGLLERTVTGAKRIRAGVPAGSRVAGKTGTGAHGTVNDIAVVWPPGREPVLIAIMSSK +SAENAEYDEALVAEAAAYVVK-- +>[subseq from] Beta-lactamase n=1 Tax=Lichenibacterium minor TaxID=2316528 RepID=A0A4Q2U5T4_9RHIZ +-----DALADLERRSGGRLGAFALDTGSGRSL-AHRADERFLMCSTTKLASVAAVLARVD +AGSERLDRRVPYTAAGIAVYAPDTKAHLADGMSLEALCRAAIVHSDNGAANLLFESLGGP +DAVTRFARGLGDPASRFDRIEPALNR--PDGERDTTTPRAFATLTRALLLGDALSPASRA +LLDGWTIDCETGGKRIRAGVPKGWTVGDKTGTAGP-VADDVALLRPPNRAPIVVAAYCDA +PGLDDDAREAVLREVGAIAAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI0013659AE2 +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSSK +DQQDADADDALISGAARAAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes aquatilis TaxID=323284 RepID=UPI000D52CADA +-----RAVQEVEQSLQARVGLAVLDTADGQWW-QYRADERFPMASTSKALICAALLARGP +---GAMKTAWLIKEEAIQSYAPTTKELIGQQVSAAQLCAITMRNSDNSAANGVLEILGGP +EAITSFLRGVGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLRNLVLGDALKASDRD +RLIDWLRHNEVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVMWPPERGPLVAAVYITE +TKASMEARNAAIATIGKAMA--- +>[subseq from] class A beta-lactamase n=1 Tax=Marinobacter sp. JSM 1782161 TaxID=2685906 RepID=UPI0014025EDB +--RLSDTVEKVENQLDARVGLSLVDTGSDFSW-AHRADERFLMNSTIKVLICGAVLARVD +EGAMALADPLPVRQDDILSYAPVTKEQVGQDMTLGELCYAALDMSDNTAANLLLEHLGGP +ASVTRFLRRIGDSVSRSDRYEPALNTGAPGDPQDTTRPVAMSGTLSKLLLGEALTADSRD +QLVAWMSHGGVTGALLRDDAPASWHIADKSGSGDT-TRNIVALITPDDGAPRIVTLYISD +ADADFRTRNAALKELGAAVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000841BE5C +----RSELAALDKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP +QAVTAFAHESGDTVFRLDRWEPELNRATPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRT +QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ +AQADAAARADVVASAARIAT--- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. WL7 TaxID=2603900 RepID=A0A5C8VED1_9RHIZ +--EAEPALAEIERRLGGRLGVSAG-TQERVLL-SHRADELFPMCSTFKALAVAAILARVD +AGSESLDRAVGFGPGILLSYAPVTRKVVEAGMTIADLCAAAIVWSDNSAANLLLTALGGP +EALTVWLRGTGDTRTRLDRDEPTLNTALPGDPRDTTTPEAMRQTLGRVLLGPVLSAASRG +QLEAWMVGCQTGAKRLRGGLPPDWIVGDKTGSGDNGTFNDVAILRPPGRAPVLACVYVTG +ATAPAAAVEAAYAEIGRLMA--- +>[subseq from] Beta-lactamase n=1 Tax=Aeromicrobium sp. MF47 TaxID=2662028 RepID=A0A5Q2MJI1_9ACTN +--DVRDGFAALETSYDTRLGVFAVDTGTGRRV-TWRGTERFPFASTIKAPLAAVVLDRTS +--RRGLARTIHYDASDLLPGSPVTEKHLADGLPLRDLIDAALRFSDNTAANLLFEQIGGP +AQLDRELDRIGDRVTNPERTEPDLNSAVPGDVRDTTTPQALATTVGEYVVGKALPRHDRD +LLRTTMVDNTTGDALIRAGVPKEWVVADRTGGASHGVRTAVAVAFPPGRSPVLIAVMSRR +DQVGDEYDDAVIAEATRIAV--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium elephantis TaxID=81858 RepID=A0A1X0D7T4_9MYCO +--TVEAQIAALEVQHGALIGVYASNLDLQRTV-AHRAQERFAMCSTFKTYAAARTLQMAE +RGELSLEQSLFVDPEDILINSPITEARAGGELTLAELCQAALQRSDNTAANMLLATLGGP +QAITAFARSIGDSESRLDRWETALNSAIPGDPRDTSTPQALGFGYRNLLAGDALAPPERS +RLEDWMRANQT--SSMRAGLPDGWTSADKTGGGDYGSTNDVGIAYGPDGQRVLLALMTRS +QTADAPGLRPLIGELTSLV---- +>[subseq from] Beta-lactamase class A n=1 Tax=Marinobacter excellens HL-55 TaxID=1305731 RepID=A0A0P8BJ49_9ALTE +------------------------------------------MSSTFKTLACAALLHRVD +AGQANPARKVNVSESDLVTYSPITEKHAGGEMTLSDLCEATLATSDNTAANLVLRELGGP +EAVTTFARHLGDDVTRLDRWETELNEALPGDNRDTTTPNAMVQNLQALLLGDVLSEQSKD +QLRSWLENNQVADGLFRAAVPEGWVVADRTGAGGFGSRSITAVIWPPERQPIVVALYLTQ +TDASFEEQNAAIAEIAEAIV--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium lehmannii TaxID=2048550 RepID=A0A124EQB4_9MYCO +---IEDRLGEMERRQNALIGVFATNLGTGHTI-AHRAQDPFAMCSTFKTYAAARVLQKAE +RGELALTDRVTIEPGDIVPNSPVTEARVGQTMTWAELCQAALQRSDNAAGNWLLRVIGGP +SGVTDFARSIGDERSRLDRWEIELNAAVPGDPRDTTTPEAIGTGYRAILTGNVLADPQRR +QLEDWMRANQT--SSVRPVLPPGWATADKTGSGDYASTNDVGIAFGPAGERLLLAIMTRT +AAPDIPNDRQLVGEVASVLV--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI000D3AABD3 +-----ESIEQIESRVSARIGVAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE +NEGLDLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAAIMEMSDNTAANIVLAGIDGP +NGLTEFLRSIGDSETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TELTMQERDTVINEIGQLIFDAy +>[subseq from] Class A beta-lactamase n=1 Tax=Advenella kashmirensis TaxID=310575 RepID=A0A356LME7_9BURK +--KTAALLTALERHYGGRLGVAIHDTANGTRV-AHRSDERFLICSTFKLLLTAAVLKRVD +NGKELLEQRITFDKSAIVQWAPVAGLNVGQPMSVLELCEATMIMSDNTAANLLLDTLGGP +AALTAYARNLGDTKTRLDHIEP-LNG-IQQGDEDTTTPESMLENMKKILLGGALSSESRA +RLVRMFEMNQTGSQALKAGLPANWRIGDKTGAASD-TSNDIAIITPPHREPLLVAAYYTN +DKVNSTVHKAVLAKVGEIVAK-- +>[subseq from] Class A beta-lactamase n=2 Tax=Streptomyces sp. GKU 895 TaxID=1662404 RepID=A0A1V4E6Y6_9ACTN +---APEGLRELEAQHGARLGVFARNIATGRTV-RYRAGELFPMCSLFKTLASAAVLRDLD +RDGEFLSRRIHYTDADLPKGSDKTREHLADGMTVAELAEVAITFSDNGAGNLLLRELGSP +TALTRFARSLGDRVTRLDRWETELNSAEPWRITDTTSPYAIGRTYGRLVLGDALDGRDRA +LLTHWLRGNTTSGTRLRAGLPRTWTVADKTGGGSYGTNNNVGIAWTEDGTPLLLAVLSTL +PEQDAVRDDVLIRDTAALL---- +>[subseq from] class A beta-lactamase n=2 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI001262578C +--ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD +AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP +AALTAYLQSIGDNVTRLDRNEPTLNEAAKHDPRDTTTPNAINHTLNTLVLGETLSSASRQ +QLKTWMQDNKVADGLLRSVLLQGFQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ +TEASFDERNAAIVTIGKSIFDTf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. UV9 TaxID=1851410 RepID=A0A4Q0GS05_9SPHN +----IREVKALEMRGVGRIGVVAIDTGTGAVV-AYRADERFPMCSTHKILVGAAILSMIS +AGRLKADQRIAYGHADLLEYAPLTTKNVEAGMTVEALGEAAVRWSDNTADNLLLTLLGGP +KGWTQFARSMGDRVSRLDRFEPDLNSGTPGDVRDTSSPRAMTGMLAALLLGRALDAGPRS +KLESWMYESPITGALFRKRLPAGWHVSDKSGSGSNGTRNDVGIIYPPRSAPIILTVFHTG +SNGSTTERDEIIAECASVVAQHf +>[subseq from] class A beta-lactamase n=1 Tax=Nocardioides alkalitolerans TaxID=281714 RepID=UPI0004299932 +--ATTAAFTALETAYDARLGVVAVELATGETV-AHRGDERFAFASTIKALQAGAVLRDAS +--DADLDRVVTYTEADLLEYAPITEQHVADGMTVRALLDASVRYSDNTAANLLFDEVGGP +AGLAEELALVDDTTTLPVREEPDLNTAVPGDERDTSTPAALAASLASYTTGCLLPEERRA +ELVDLLERNTTGDALVRAGAPEGWTIGDKTGSASYGTRNDIAIAWPPDRSPVAIAVLTSQ +DEQDDPTLDALVADATREAF--- +>[subseq from] class A beta-lactamase n=1 Tax=Aestuariispira insulae TaxID=1461337 RepID=UPI000E27C4ED +------ALPDIENRLKARLGAYILDTETNRVW-QHRARERFPLNSTFKAFACAGILAKTD +RGEDILDTEISFGKADLVTYSPVTEGFAGVAMPLSSICQAAMHMSDNTAANLVLDQLGGP +EGFNGFMQEIGDHTTRLDRWEPELNEAAPGDPRDTTSPEAAANSLMALALGDRLSPASRA +QLNRWLEGNQVSGPLFRSSLPKDWLIGDRSGAGGHGSRSIIAVLRPPKRKPVIAAVYITD +TSASFELRNNAIAVIGEKLM--- +>[subseq from] Beta-lactamase n=1 Tax=Virgibacillus dokdonensis TaxID=302167 RepID=A0A3E0WML7_9BACI +----ESEFRLLEKAYNAKLGIYAVDTSNGKTV-SYQAEDRFAYASTHKALAVGVLLQKLT +--LKQLKETVLIKEKDLVNYNPITENHVNKHMSWKELSDASIRYSDNTAANHILNRIGGP +NGFKKALRDIEDDVTNPKRMEPELNLVNPGEIKDTSTPKALATSLKAFTMGNVLPKEKQD +LLVDWLKRNTTGDHLIRAGSPRGWEVGDKSGAAPYGVRNDIAIIWPPNKAPIILAILSSK +EEKNAEADDKLIAEATKKVI--- +>[subseq from] Beta-lactamase n=2 Tax=Mycobacteriaceae TaxID=1762 RepID=A0A5Q5CF05_MYCSJ +-------LDALERANNAVVGVFAVNLDTGRTV-AHRAQESFAMCSTFKAYLAAHVLQLVG +RGERSLEQGLYVDAADILPNSPRTEPRVGGEMTLAELCQAILQVSDNAAANILLRDVGGP +PAVTAFARGIGDPRSRLDRYEIELNSAVPGDPRDTSTPEALGGGFRTLLTGDVLAPPQRR +LLEDWMRANET--SSMRAGLPPGWTTADKTGSGDYGTTNDVGIAYGPQGQRLLLAVMTRS +ATPDAENMRPLIGEVTAAVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075E10DA +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPIEMIDTLQRLLLGNTLPDPQRG +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio kanaloae TaxID=170673 RepID=A0A4U1ZKL9_9VIBR +------SIAKIESRISARIGVAVYDSATEQIW-NYKGDERFPMMSTFKTLTCANLLYDHE +SEGLDLESKVGIEPDELIAWSPITKSFVGKEISLRSACAATMEMSDNTAANIVLRSTGGP +NGLTEFLRFMGDRKTRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWRIADRSGAGAYGSRAITAIVWSETHAPLIISISLTE +TELTIPERDTVINEIGELVFDEy +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SCZ2_9BACT +--TLSKAVQAEEARLGARIGMAVFDAKDRTRW-AHRGDERFPLNSTHKSFSCAALLKQVD +RRVLALENVISIERASLVTYSPVMEKT-GGQVTLREACAASVSWSDNTAANIVTDAIGGP +QAFTVFMRDIGDPHTRLDRKEPEMNEATPNDLRDTTTPNAIVESLRRIILGDVLREDSRA +LLTDWMINDKVADALLRATLPRTWSIADKSGAGGHGSRSIVAVIWPKDRDPVVVGIYITQ +TSAPMADSNAAIARLGSVLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium PA3 TaxID=2015571 RepID=A0A257JTJ8_9PROT +----AEELQALEARSQGRLGVGILDTATGELV-GHRQDERFAMCSTFKLPLAAEVLRDVD +AGKRKLDQFIAYSKADMVSHAPVTGANLAAGMTIGDLAKATQITSDNPAANLIIRELGGP +TEVTQRFRSAGDPVTRIDRYEPMMNFVVGDDPRDTTSPAAMAGLIARYLTTDYLSKASKD +LLIGWMVETQTGAKRIRAGLPGEWKAGDKTGTGMADKYNDVAIFWPTGRAPIIVAAYYET +AIDTRDEFQAVLAEAGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio ostreicida TaxID=526588 RepID=UPI000970C5DB +----------VSTSLGARVGVFVNNTNTNQQW-GYNGDQRFPTASTFKVLACAAALDKGA +-----LSKTVMITEKDLVEYSPVTGKHLNKTLTYEQLCHATITTSDNTAGNLVLKYVGGP +EGLTQFLRGTGDSVTLMSRWEPELNQGTPGDKRDTTTPAAINRTLDALLFGDVLSKPKQQ +QLLQWMKQDQVADDLLRSVLPKTWQIGDKTGAGGHGSRGIIAVLIPPKSKPVLVSIYITE +SQTTIKQLNKAIATIGSAIIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. djl-10 TaxID=1879023 RepID=UPI000811B40E +----AERLAELERRHNAMVGLYAVDLQTGRTL-VHRENERFAVCSTFKAYLAARTLQAAG +RGEFAMTDTVTVRAEDLLPNSPVTETRVGQTITLAELCAAVLQVSDNAGANYLLHQIGGP +PAITEFARSIGDQETRLDRWETELNSAVPGDPRDTSTPTALGNGFRALITGDALEPQART +QLVDWMLANTT--SSLRPGLPADWTFADKTGSGDYGTTNDIGVAFGPDGRAVLLSVMLRS +ASPDTEGFRPVMPEIATLVLQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_003 TaxID=2175667 RepID=UPI000DAACE78 +----APAFDRLQQTYGATLGVFALDTGTRQTV-AYNANRRFAYASTYKALAAGVLLADPS +---TDLDAHVDLAQDEILAGSPVTSQHVESGMRLGDVVAAALEQSDNTAGNIVLQRVGGP +AGFETALRRIGDTTTRSDRTEPDLNAAVPGDDRDTSTPRALALDLDRLVLGSVLHASERA +RLTVWMRANTTGDDLVRAAVPAGWTVADKTGTGYYGVRNDIAVVWPPSGAPIVLAIQTTK +STQAAEPSDALVAAAAKEAI--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium riyadhense TaxID=486698 RepID=A0A1X2CSR3_9MYCO +--DIAARFSELERNYEARLGVYVPA----AQI-AYRADERFAFCSTFKAPLVAAVLHQFP +--LPHLDKVITYTSDDIRSTSPVTQQHVATGMTIGQLCDAAIRYSDGTAANLLLADIGGT +ATFTGYLRELGDTVSRLDQVEPELNRDAPDDQRDTTTPHAIALVFQQLVLGNALPADKKA +MLIDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDVAVVWSPTGVANVVAIYSDR +AAYDAEPSDGLIAEAAALVA--- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella TaxID=570 RepID=A0A1G5SA95_KLEPN +---------RLERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGT----------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis halotolerans TaxID=124252 RepID=UPI000A3142B7 +----DSAFARLEGEFGVRLGVYALDTGTGQAV-EFQSDERFAYCSTFKALAFGAVLDRTP +--IDELDRTVTFSEADLVFHSPVTREHVATGMTLREIGDAALRHSDNTASNLLLQELGGP +EELERALRGIGDEVTRVDRVAPEMAEAVPGDVRDTSTPRAMATSLREFALGDVLSEDKRD +ILTGMMRANTTGDDLIRAGVPEDWTVGDKTGACGYGTRHDIGVLWPPEGAPV-------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI000247844E +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTTITKEQIMPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSKTLNALLFGNTLNPQDKQ +TLKSWMMNNKVSDPLLRSILPSDWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000F67A616 +-----QAAQEAEQSLQARIGLAVLDTADGQLW-QYRADERFPMASTSKALICSALLARGP +---GAMKTAWLIKEEAVQSYAPTTENLIGQYVSAAQLCAITMRNSDNTAANGVLEMLGGP +QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDAFKTSDRD +RLTDWLRHNEVGGPLLRAGVPESWNVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE +TKASMEARNAAIAAIGKVIAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Aestuariispira insulae TaxID=1461337 RepID=A0A3D9HMY0_9PROT +------ALPDIENRLKARLGAYILDTETNRVW-QHRARERFPLNSTFKAFACAGILAKTD +RGEDILDTEISFGKADLVTYSPVTEGFAGVAMPLSSICQAAMHMSDNTAANLVLDQLGGP +EGFNGFMQEIGDHTTRLDRWEPELNEAAPGDPRDTTSPEAAANSLMALALGDRLSPASRA +QLNRWLEGNQVSGPLFRSSLPKDWLIGDRSGAGGHGSRSIIAVLRPPKRKPVIAAVYITD +TSASFELRNNAIAVIGEKLM--- +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI00052D8055 +----AQAAQVVEQSLQARVGLAVLDTTDGQLW-QYRADERFPMASTSKALICAALLARGP +---GAMKTAWLVKEEAIQSYAPTTENLIGQYVPASQLCAITMRNSDNTAANGVLEMLSGP +EAITSFLRSVGDTVTRLDRNEPSLNEATPGDPRDTTTPQAMVHTLQNLVLGDALKAPDRD +RLIDWLRHNEVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVMWPPGRAPLVAAVYITE +TKASMEERNAAIATIGKAIA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A2Z6A9H1_SHIFL +----------------------ELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELSSPAINMSGNTAANLLLTTTRGP +KELTAFLHNMGDHVTRLNRGEPELNEAIPNDEHDTTVPAAMATTLRKLLTGELLTLTSQQ +QLIDWMEAVKVAEPLLRSALPAGWFIADKSGAGERGSRGIIASLGPDGKPSRIVVIYTTG +SQAIMDESNRHIAEIGASLI--- +>[subseq from] Uncharacterized protein n=1 Tax=Nocardioides luteus TaxID=1844 RepID=A0A1J4N769_9ACTN +------SIDALEQKHQRHLGVWAQNVRTGRVV-EHRADERFPMLSTFKTLLVSAILRDLP +--ARTLQQRLTWDDADVVVNSPVTSLTTRNGLTVAQLAEATMTRSDNTAANELLQLIGGP +AGVTSLARSLGDTVSRLDRWEPDLNSAIPGDPRDTTSPRAIARTYTKLVLGDALGGADRD +QLLTWMLANQSTVSRFGAGVPAGWRLADKTGGGDYASRNDVGVTWTPDGAPIVIAALTRS +DDPAAPPLDAPLADIAATVCA-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio TaxID=662 RepID=UPI0009899530 +------SIAKIESRISARIGVAVYDSATEQIW-NYKGDERFPMMSTFKTLTCANLLYDHE +SEGLDLESKVGIEPDELIAWSPITKSFVGKEISLRSACAATMEMSDNTAANIVLRSTGGP +NGLTEFLRFMGDRKTRLDHIEPDLNHARPGDERNTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWRIADRSGAGAYGSRAITAIVWSETHAPLIISISLTE +TELTIPERDTVINEIGELVFDEy +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio sp. 624788 TaxID=1234362 RepID=UPI000474F6E2 +----AQSIAQIESRVSARIGVAVYDSATEQTW-SYKSDERFPMMSTFKTLACANLLYVHE +HEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLRDACASTMEMSDNTAANIVLASTGGP +NGLTEFLRSTGDSKTRIDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMGNKVSDGMIRSILPDGWKIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TELTISERDTVINEIGELIFDEy +>[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus sp. CUA-806 TaxID=1517936 RepID=A0A1Q9U3C4_9NOCA +--AIEDDMTALEQRYGARIGVWASDLTSAATA-SHRPHESFAMCSTFKPYAVAAALQLAS +RGRLNLDEVVPVTAADIVVNSPVVSNLIGGSITLSQACDAALTQSDNTAGNILLRAIGGP +PAIAAFARSVGDPRTQLDRWEPELNEALPGDLRDTTTPEALAAGYRAILIGDMLEKSHRD +RLVGWMRATRTSDKRFRAGLPQGWSSADKTGAGDYGSTNDAGLLLGPSGQEILVVVMTRS +RDKDAPPFNDAIADTVRLTLSKf +>[subseq from] class A beta-lactamase n=1 Tax=Roseomonas aerilata TaxID=452982 RepID=UPI0012EC9C05 +-----AALREAERAGGGRLGVAVLDTATRAWA-TWRGAERFPLASTFKLVLAGAVLREVD +EGREDLERRVPIEASDLVDYAPVTEKRVGPEMRVGELLEAVMVWSDNAAANLLLPLVGGP +EGLTERAGDWGDAGFRLDRRETALGEGRPGDPRDTTTPNFMLVSMERLLVGNLLSAPLRG +LLNAWMIGCRTGDTKIRAGLPQGWICGNRSGAAGFGTSNDVAAIWPPGGRPILVAAYLTE +SAAPLQARDAALAAVGRAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI00142F817E +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSSK +DQQDADADDALISGAARAAAQ-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9131 TaxID=2184571 RepID=A0A3N8AQT1_9BURK +---AQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTALLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTAFRLDRWEPELNQAAPGDERDTSTPVAMVDMLQRLLLGDTLREPQRA +QLTEWMTGGAT---GIAAGVPPGWRSAGKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 852014-52144_SCH5372336 TaxID=1834115 RepID=A0A1A0USS0_9MYCO +---IEDRLGEMERRQNALIGVFATNLGTGRTI-AHRAQDPFAMCSTFKTYAAARVLQKAE +RGELALTDRITIEPGDIVPNSPVTEAHVGQTMTLAQLCQAALQRSDNAAGNWLLRVIGGP +SGVTDFARSIGDERSRLDRWEIELNAAVPGDPRDTTTPEAIGNGYRAILTGNALAEPQRR +HLEDWMRANQT--SSVRPVLPPGWATADKTGSGDFASTNDVGIAFGPAGERLLLAIMTRT +AAPDVPNDRQLVGEVASVLV--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=A0A2N7K9D4_9VIBR +-----ESIEQIESRVSARIGVSVYDSATKKTW-SYKGDERFPMMSTFKTLACANLLYDSE +NEGLDLESKVGVKSDELIAWSPMTKAFVGKEISLTGACSATMEMSDNTAANIVLAGIDGP +NGLTEFLRSIGDRETRLDHIEPDLNHARPGDVRDTTTPNTMVKTLNELVYGNVLSEASKA +QLKTWMKDNKVSDGMIRSILPDGWKIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TKLTIPERDTVINEIGELIFDDy +>[subseq from] Class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A2U2BNW9_ALCFA +-----QAAQEAEQSLQARIGLAVLDTADGQLW-LYRADERFPMASTSKALICSALLARGP +---GAMKTAWLIKEEAVQSYAPTTENLIGQYVSAAQLCAITMRNSDNTAANGVLEMLGGP +QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDALKISDRD +RLTDWLRHNEVGGPLLRAGVPESWTVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE +TKASMEARNAAIAAIGKVIAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI000D0809B6 +--ALVDIIKQQEKALNGIIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KDKSVLTHSVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRLVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ +SSASMDERNKAIATIGKQVFTYf +>[subseq from] class A beta-lactamase n=1 Tax=Aquidulcibacter paucihalophilus TaxID=1978549 RepID=UPI000A1907CA +---PTAELAALEASSQGRLGVALLDTATSELV-GHRQDERFALCSTFKLPLAAEVLRDVD +AGTRKLDQFIPYSAADMVAHAPVTGANLSAGMTIGDLAKAAQITSDNPAANLMMAELGGP +EGMTQRFRAAGDAVTRLDRYEPMMNHVTAGDPRDTTSPAAMVRLIARYLTTDYLSQASKD +LLVGWMIETQTGLKRIRAGLPAAWKAGDKTGTAMTDKYNDVAIVWPPGRAPILIAAYFNT +LIETRDEFQAVLAEVGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 852013-51886_SCH5428379 TaxID=1834111 RepID=A0A1A0TBZ2_9MYCO +-----DRIGALERRYDAVIGVYAVDLASGRTV-AHRAQETFALCSTFKGYLAALVLRMVG +RGERSLEQRLYVDPAAILPNSPRTEPRAGGDMSIDELCQAILQVSDNAAANILLHNVGGP +AAVTEFARSIGDPRSRLDRFEIELNSAVPGDPRDTSTPEAVGNGYRALLAGDALMPAQRQ +LLEDWMRANET--SSMRAGLPPGWTSADKTGSGDYGTTNDVGIAYGPQGQRVLLAVMTRS +AAAEAENNRPMIGEVASVVMQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Colwellia piezophila TaxID=211668 RepID=UPI0003AAD9A4 +---ITKKIEEIENKLGARIGASIYDVTDNKFW-SYKGDTRFPLLSTFKTLACAKLLADVE +KGLQSFETSSVITTSSLVKWSPVTKNHVGEKFSLKQACSAAMIMSDNTATNIVLTGIKGP +KALTHFMRSIGDDVTRLDRIEPYLNEALDGDKRDTTTPNAMVKSLHTLLFGDALSQASKA +QLKQWMIDNKVTGSLLRSVLPENWSIADRSGAGGNGSRAITAVIWSDKRSPLIISIYLTQ +TDASFALRNKAIADIGKEMFTVy +>[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter gallaeciensis TaxID=60890 RepID=UPI000BBCDA18 +--DLAETIRSWETALDARLGVLLIHPATGWEI-AHSADDRFPLNSTFKPLLCAAILSQVD +QGTEDLTARVEIRRGDLVSHSPVIERYIGTTRSLAQLCEATITRSDNTAANLLLERIGGP +EGFTEFMQISGDLITRLDRWETGLNSATPGDHRDSTTPRSVLSTLYLALSGTILSGPSSA +QLTDWMQRDQLADDLIRAHLPEGWTIGDKTGAGGHGSRGIIAFLRDPQGSEYLAAIYITE +TDANFARRNQAISDIGRAMI--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium palauense TaxID=2034511 RepID=UPI000BFEE842 +---VDERLRTVERLHNASIGVYAVDLDSGRNY-ASLADERFALCSTFKTYAAARVLQMAA +GGELHLQDEVFVDPTAVVDYSPVTAPLAGVQITLETACRAALQHSDNTAGNLLLARIGGP +PAVTAFARSIGDQQTRLDRWETDLNTAAPGDPRDTSTPRALGEGYRALLVGDALDEASRG +TLVTWMRGNVTSVHSMRAGLPADWTTADKTGAGGYGSTNDVGVVFRPGGGRLLLSVMCRS +RTDDAESSQRMIAQVTAAML--- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC310 TaxID=1848322 RepID=A0A4R4W207_9ACTN +----RKELRKLEVAFKGRIGAYALDTATGKTV-TYRAGERFPMLSTFKAPLCAAVLQKAR +TSRGLMSRLIKWTAADMKPNSPVTEKHVKDGLTVSQLCEAAVTMSDGTASNLLLKQIGGP +KGLTKYFRTLKDSTSRMDRWHPELNDWTPREKRDTTTPAAIGRDLRVLTLGRALHAKDRR +QLLAWLLANKTGGERIRAGLPGTWTVADKTGTNSFGGGNDIAVVWPGKGAPLIMSIYTNR +TK-GLPTDNKTIAKTATVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Kineococcus rhizosphaerae TaxID=559628 RepID=A0A2T0R071_9ACTN +--AVQARFAQLEESFDARLGVFAVDTGSGRTV-VHRGDERFGFASTYKALAAGALLERTG +--DAELDAVVTWTADEVVAHSPVTGQHTASGLPLRQVAEAAVTVSDNTAANVVLAHLGGP +AGLEEDLRALGDDTTEVEHTEPDVNDITPGDPADTSTPRAMATTLQAYATGDVLAPAGRD +QLVRWLQAGTTGGGQIRAGVPAGWVVGDKTGHAGYGNQNDIGVVWPTGGAPWVLAILTDR +ADVDATSDEALLARATEVVVDE- +>[subseq from] Beta-lactamase n=8 Tax=Bacteria TaxID=2 RepID=A1E3K9_ECOLX +--SIDDTVKQVETTLGAKVGIAVLDTGSQRAW-FHRADDRFPMASTSKALTCAALLDK-- +-GQSFMNKEALIKKADLDEYAPVTSGIVGKKVSAADLCSITMRTSDNTAVNKVLEILGGP +QAVTAYLRKTGDNITRLDRNEPDLNEGTPGDVRDTTTPRAILETLNKLVLGPTLGSDERK +QLTTWLESNEVGDPLLRAGVPSDWRVADRTGAGGNGTRGVIAVMWPPKHAPIIAAIYITQ +TKATMEERNAAIASIGKAIAA-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacteraceae bacterium TaxID=2052182 RepID=A0A522RLC4_9GAMM +----GARLSALEQQHGGRLGVAILDTGSGLRA-AHRGGERFLMCSTFKLLLAAAVLTRVE +HGEEKLDRRIVFNESVVLDYAPITKQRVGPPMTIAELCEAAITLSDNTAANLLLEAIGGP +AAVTQYARTLGDTFTLLDRTEPSLNPY------DTTTPLAMLGDMQEVLLGDALLQTSRK +RLTHWLLDCQTGLQSLRAGLPSGWGIGDKTGQWDAGANNDIAIIWPPGRKPLLVTAYYMN +HTTDPVGRKAVLAEVGRIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Vibrio sp. V24_P1S3T111 TaxID=1938676 RepID=A0A6B2BNK6_9VIBR +--QLTQAVKDIESDWQGRIGVYAYDINGSFTF-GYREQERFPLCSSFKSLLAAAILQKSQ +NQLLNLETFIDFSKRELEFWSPITEKNHATGMSIGELAQAALQYSDNGATNILLERIGGP +QGMNNFMKSIADQDFRLDRWELELNTAIPGDERDTSTPRSMATSLGKLSFSNVLTASHQN +LFHDWLIGNTTGDNRIRAVVPKQWKVGDKTGTCGYGAASDVAVIWREKASPLVIAIYTHK +SEPTAKHSDKLIAEVAKETLQ-- +>[subseq from] Beta-lactamase n=1 Tax=Kribbella sp. VKM Ac-2527 TaxID=2512215 RepID=A0A4R6JNK4_9ACTN +--DLKGRLQDLERDKDCRIGAYALDVGNGRTV-RYRGDERFPVLSTFKAFLGAAMLDRSR +YEPGLLRKRLTWAKADLVANSPITSQHIDDGLTVAELCWAAICVSDNTAANVLLKQIGGP +DGLTCFIRRLGDPVTRLDRWEIELNNWSPSERRDTTTPTAAGRSLRMLTVGGGLHPADRT +ALIAWMRAARTGGKRIRAGLPKTWIVGDKTGTSSYGSANDIAIAHPRSGAPLILAIYTNR +SQPTQVTDEAIIASTATALAQ-- +>[subseq from] Beta-lactamase n=3 Tax=Mycobacterium TaxID=1763 RepID=A0PQQ2_MYCUA +--DLESRFAELEQKYEARLGVYVPGTDATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYS +--IAHLGTVITYNSADIRSTSPIIEQHLATGMSIGGLCDATIRYSDGTAANLLLQDIGGI +AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALLPEKRD +KLIDWLGRSTTGAKRIRAGFPADWRVIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR +VGPEAPWCDPLVADAAKCVAD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A2S9M1E4_9BURK +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMTAGAR-GDGIAAAVPPGWRAAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI000D3C4404 +-----ESIEQIESRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE +NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP +NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWIETRAPLIISISLTE +TELTMQERDTVINEIGQLIFDAy +>[subseq from] Beta-lactamase n=2 Tax=Actinomadura umbrina TaxID=111806 RepID=A0A3D9SPP0_9ACTN +--EVTKRLRALETAYRGRIGAFALDTGTGRVV-GHRAQERFPFLSTFKALAAGAVLSRAH +RDPGLMDRVVHWTSEEVKPNSPITEKHTGPDLTVARLCDAAIRYSDNTAGNMLLKQLGGP +AGLTGFLRSLGDPVSRLDRWEIELNDWSPGERRDTTTPARAGTDLHRLTAGGSLVPQDRA +RLVGWLRGNTTGDTRIRAGLP-NWTVGDKTGSNG-GMANDIAIAWPPGSAPVILAVYTHR +LDPTAPREDEVVADAAAILA--- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_040 TaxID=2175674 RepID=A0A2W1Z7T1_9MICO +----APAFDRLQQTYGATLGVFALDTGTRQTV-AHNANRRFAYASTYKSLAAGVLLADPS +---TDLDAHVDLAQDEILAGSPVASQHVESGMRLGDVVAAALEQSDNTAGNIVLQRVGGP +AGFETALRRIGDTTTRSDRTEPDLNAAVPGDDRDTSTPRALALDLDRLVLGSVLHASERA +RLIGWMRANTTGDDLVRAAVPAGWTVADKTGTGYYGVRNDIAVVWPPSGAPIVLAIQTTK +STQAAEPSDALVAAAAKEAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia TaxID=32008 RepID=UPI00064E626F +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVVSAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella sp. J329 TaxID=1977852 RepID=UPI000FDA0DDC +--TLSKAVQAEEARLGARIGMAVFDAKDRTHW-AHRGDERFPLNSTHKSFSCAALLKQVD +RRVLALENVISIERASLVTYSPVMEKT-GGQVTLREACAASVSWSDNTAANIVTDAIGGP +QAFTVFMRDIGDPHTRLDRKEPEMNEATPNDLRDTTTPNAIVESLRRIILGDVLREDSRA +LLTDWMINDKVADALLRATLPRTWSIADKSGAGGHGSRSIVAVIWPKDRDPVVVGIYITQ +TSAPMADSNAAIARLGSVLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea phyllanthi TaxID=2219224 RepID=A0A5C4W7D6_9ACTN +--QARKELRALEKKFGGRIGAYAIDTATGKTI-AYRSAERFPLLSTFKAMACAAVLHKAR +TEPGLMDKVVHWTAGEVKPNSPTTSKHVKDGLTVSRLCEAAITLSDNTAGNMVLKQIGGP +AGLTRYFRTLKDPLSRLDRWETELNDWTPKDRRDTTTPAAIARDLRAVTVGSALDARDRR +RLNAWLRATETGDARIRAGLPKGWTVGDKTGSNSFGGGNDIAVVWPGKGAPIVMAVYTHR +AA-GQAGDDTAIARTATILA--- +>[subseq from] Beta-lactamase n=1 Tax=Lechevalieria fradiae TaxID=200378 RepID=A0A1G7R930_9PSEU +----TGRLRELERRHGARLGVFALDTGSGRTV-LHRADELFPMCSTFKTLAAAAVLRRDV +-DGSLLGKVITYTQAEADKYAPITGANLANGMTVSALCEATITYSDNCAANLLLRELGGP +TAISRFARSIGDPVTRLDRYEPELNSAEPGRRTDTTSPRAIGQSYARLTLGHALDRPDAE +QLTNWLLANTTGGNRVRAGLPAEWGWGDKTGGGSYGTTNDVGIAFPPGRAPIVIATLSTR +ESPDGGADEPLLVKTAQLLAETf +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. URHA0002 TaxID=1298867 RepID=UPI0004877F40 +-------LLAYERDTGGRIGVHAENISTGAKI-AWRAEERFVMCSTFKASLAAFVLARVD +NASDRLDEMVAYGPKDLLDYAPVAKQNLAQGMSVSDMCKAIVELSDNTCANLLLARVGGP +AALTEFWRRAGDTVSRLDHNEPELNRSPPGDIHDTTTPSAMAGNLRRFVLGTVLTPSSRE +QLTLWMVDCKTGNNRLRGGLPADWKVGDKTGNNSKDASGDIAIAWPKSGGAVLVAAYTQG +GSPTRQQLEAVFKEIGAMV---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SAV6_KLEPN +--------AELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYG------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Bombella sp. KACC 21507 TaxID=2697033 RepID=UPI0013668ECA +--SLEPDFAAIERRSGGKIGVSVLDTETGKTL-QWRANDRFPFCSSAKVPLVAYVLWKAD +RGEISLDQIVHYTEADLLPYAPVTRVAVSKGLSIAELCQAAVTLSDNTAANLLWRETGGY +KALNAWMQSEGDHEFNLSGIEPELNWAQYGDRHNTTTPVAMAKTYERFVLGDTLKSASRD +KLTNWLLSNKTGERRIRAGLPHAWRVGDKTGTFNYFSTVDIGVVWPIARRPMVIACFVAG +TP-DTDSAEYAIAEAAQAIA--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T6B9_9BACT +---VLTEIKRVERELDARVGVSIYDVKTKKLW-SYNGEARFPLLSTFKTLACAKLLVDSD +KGNISIYTSVEVHSESLMEYSPVLEKYVGKKITLGEACSATMQMSDNTAANIILTSIGGP +QELTKFMLGIGDSVTRLDRIEPSLNEALATDVRDTTSPNAMTKTLNTLLFGTVLSTESKA +KLKQWMVENKVSGSLFRSELPSGWYIADRSGAGGNGSRAITAIIWSNERSPLIVSVYLTQ +TEASFENRNKAIAKIGKEIFKQy +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=A0A4R7QGV4_9BURK +----TNPINNIERRHGGRLGVFAIDTGSGRTL-AYRADERFLMCSTFKGLLAAQVLTRVD +AGKENLDRLVHYTEKDLIFTSPVTKANVAQGMSVRAMCQAIVEVSDNTAATLLMRDAGGP +PALTQFVRSLGDTVTRSDRYEPDSNQY--SGARDTTTPKAITKSVGKILLGNVLSAQSRQ +QLESWMIDCEPGLDRIRAALPTDWVAADRPGTSVEEETNDYAIVRPPGRAPLLVAAYYDA +PYVDMDGREAVLREVGAAFVD-- +>[subseq from] Beta-lactamase n=2 Tax=Acetobacter malorum TaxID=178901 RepID=A0A177GA41_9PROT +---VASVLSEYEDATGGRIGVYARNLVTGQSL-TWRENERFAVCSTFKASLVALVLLRVE +QGHERLEDMVPYTQADVEKYAPVAQAHVEDGLTVRTLCQAALEQSDNACANLLLARVGGP +AMLTRFWRSLGDTKTRLDDWEPVLNRTPPGGLRNTTTPRAMAGTLEHVLFGDTLSVSSRT +LLTDWLKGCRTGTHRLRAGLPEGWGVGDKTGNNGRDAVSDIAVAWPAPQRPIILSVYTRG +GHPVEEQFRTAFAGIGRMV---- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) TaxID=482957 RepID=A0A3G3HB92_BURL3 +--AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTAFARASGDASFRLDHWEPELNNAAPGDERDTSTPVGMVDTLQRLLLGNTLLEPQRT +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Uncharacterized protein n=1 Tax=Agrobacterium sp. SCN 61-19 TaxID=1660088 RepID=A0A1E3YGY0_9RHIZ +-----AAAQRMEQKLGMRVGLSVIDTGRGTVV-AYRETERFAMASTFKSLACAAALSGGD +---AVLEQTTRITKADLRPHSPVTEKRVGTSLSTRELCEITLRTSDNAAANAILKVLGGP +AEVTSFLRGIGDTTTRLDRYEPEVNEATPGDPRDATTPQAMAQTLERLLVGAALAPADRD +QLDAWMSANAVADGLLRSRLPKGWQIADRSGAGGHGTRGVIAVVRPPGAQPLVIAIYMDG +KTHPLKTRDAAIAEIGATIFAGy +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00068D0026 +---LARRFRALEEEYAARLGVYAYDTATGRSV-RYRADETFALCSVFKTLAAGAVLRDLD +RNGEFLAKRIRYTEQQVTDYAPVTGRNLADGMTVEALCAAAVSESDNCAGNLLLSELGGP +TGITRFCRSLGDRTTRLDRWEPDLNSAEPWRTTDITTPHAIGRTYARLLLGRALPDADRE +RLTGWLIANTTNGERFGTGLPDDWTLADKTGGGSYGVANDVGVAWPPGRPPLLLAVLSTK +KDPAGPTENALVARAAAQVA--- +>[subseq from] Beta-lactamase n=2 Tax=Mycolicibacterium gilvum TaxID=1804 RepID=E6TFK0_MYCSR +----EERIAALAARHDARIGLYAADLDSGATL-AFGDTDTFAVCSTFKTYAAGAVLQRVQ +QGRLGLGDTVLIEAADIRPHSPVTEPRVGTAMTLAELCQAALQQSDNAAANGLLRVLGGP +SAITEFARSIGDDRTRLDRWEVELNSAVPGDPRDTSTPRALATGYQALLTGDVLDPIGRR +QLVDWMLANQT--SSMRAGLPAGYTSADKTGSGDYGSTNDVGIAFGPAGQRLLLAVMTRS +ASPDAPSLRPLIGELATLVL--- +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=T0IN24_9SPHN +--------KDIEQETGGRLGVALVDKEGALIL-GFNRDDRFAMCSTFKAPLAAAVLMGAD +AGKFGLEGQIPFTKNDILDYAPVVKQNRKRGMSMAELAEAAVEVSDNSAANLLLPMLGGP +QGLTAFFRAYGDKVTRLDRNEPTLNENAEGDPRDTTTPAAMAGLMARLLFRDM-KPESAE +RLRGWLNANTTGDKRIKAGLPEGWTSGSKTGTCGN-AYNDVALVKSPKGDEYILAVYLDR +PTVDQKASEAAIAEAARAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFB6B1 +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVITAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESQADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0009082A20 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTTITKEQIMPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +ALKSWMMNNKVSDPLLRSILPSDWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus Rock3-29 TaxID=526984 RepID=C2V7Y8_BACCE +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLIKNS +--LEALDQKIRYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNQLFLLYF--- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio kanaloae TaxID=170673 RepID=UPI0011B6E415 +------SIAKIESRISARIGVAVYDSATGQIW-NYKGDERFPMMSTFKTLTCANLLYDHE +SEGLDLESKVGIEPDELIAWSPITKSFVGKEISLRSACAATMEMSDNTAANIVLRSTGGP +SGLTEFLRFMGDRKTRLDHIEPDLNHARPGDQRDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TELAIPERDTVINEIGELVFDGy +>[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI00126223D9 +--ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD +AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGS +AALTAYLQSIGDNVTRLDRNEPTLNEAVKNDPRDTTTPNAINHSLNTLVLGETLSSTSRQ +QLKTWMQDNKVADGLLRSVLPQGFQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ +TEATFDERNTAIVAIGKSIFDTf +>[subseq from] Beta-lactamase class A n=3 Tax=Streptomycetaceae TaxID=2062 RepID=A0A3N1YHI5_9ACTN +--RLADSFRQLEREHGARLGVLAHDTGSGATV-RYRADEAFPLCSTFKPLAVAALMRAGD +----DLSARVHYTDADVADHAPVTGR--TRVLTVAELCAAAIEFSDNTAANLLLRRLGGP +TAVTRFCRSLGDPATRLDRWEPALNSAEPDRSTDTTTPHALARTFARLTLGDALARPHRA +RLTAWLRASTTGTHRLRAGLPPSWALADKTGTGSYGTANDLALAWPPHRPPLVLAVLSTR +PTAPAAPDEPLLARTAALLA--- +>[subseq from] Beta-lactamase n=1 Tax=Virgibacillus chiguensis TaxID=411959 RepID=A0A1M5XC82_9BACI +----ESEFRLLEKAYNAKLGIYAVDTSNGKTV-SYQAEDRFAYASTHKALAVGVLLQKLT +--LKQLKETVLIKEGDLVNYNPITENHVNKHMSWKELGDASIRYSDNTAANHILNRIGGP +NGFKKALRDIGDDVTNPERREPELNLVNPGEIKDTSTPKALATSLKAFTMGNVLPKEKQD +LLVDWLKRNTTGDHLIRAGTPRGWEVGDKSGAAPYGVRNDIAIIWPPNKAPIILAILSSK +EGKNAEADDKLIAEATKKVI--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. E740 TaxID=1834149 RepID=A0A1A3C559_9MYCO +-----DRIGELEARHNALIGVFAVNLDTERTI-AHRAQDSFAMCSTFKGYAAARVLQKAE +RGELALTDRVTIERSDILPNSPVTETRVGQSMTLAELCEAALQQSDNAAANWLLRVLGGP +SAITDFARSIGDPRSRLDRWETELNTAIPGDLRDTSTPEAIGGGFRSILTGAVLAEPQRR +QLDEWMRANRT--SSVRPALPPGWTTADKTGSGDYASTNDVGIAYGPNGERLLLSIMTRT +AGPSTPNNRALIAELAGLL---- +>[subseq from] Beta-lactamase n=1 Tax=Actinosynnema sp. ALI-1.44 TaxID=1933779 RepID=A0A1V2PP91_9PSEU +---YTTDFAALEKRFDARLGLFAVDVTTRRTV-GHREEERFAICSVFKGYAAGALLKANP +LSSGFFKKTIKFAASDLVDGSPVTSTRVQSGMTVAELCHAAITRSDNTAGNQMLKLLGGP +TKLTEFARSIGDPMTRLDRWETALNVVPRGTEQDTTTPSAIAKAYQMLVVGDTLGAPERQ +QLKDWLVANTTGGERIRAGLPPTWVTGDKTGTGSFAAANDVAVTWPSPDKPIVIAVLTDK +AAEDAKYDSALLAEATKVAIK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia puraquae TaxID=1904757 RepID=A0A1X1PNH8_9BURK +--AAQAELTALEKASNGRLGVDALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARESGDTFFRLDHWEPELNNAAPGDERDTSTPVAMVDTLQRLLLGNTLQAPQRA +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. IS-1590 TaxID=1772286 RepID=A0A101BJS6_9MYCO +---VEDRLGEMERRQNALIGVFATDLGTGRTI-AHRAQDMFAMCSTFKTYAAARVLQKAE +RGELALTDRVTIEPGDIVPNSPVSEAHVGQTMTLAQLCQAALQRSDNAAANWLLRVIGGP +SGVTDFARSIGDQRSRLDRWEIELNAAVPADPRDTTTPEAIGAGYRSILTGDVLAEPQRR +QLDDWMRANQT--SSVRPVLPPGWATADKTGSGDYASTNDVGIAYGPVGERLLLAIMTRT +AAPDVPNDRQLVGYVASVLV--- +>[subseq from] Beta-lactamase n=2 Tax=Acetobacter malorum TaxID=178901 RepID=A0A149R5M7_9PROT +---VASVLSEYEDATGGRIGVYARNLVTGQAL-TWRENERFAVCSTFKASLVALVLLRVD +QGKERLEEVVPYTQADVEKYAPVAQAHVEAGLTVRTLCQAALEQSDNACANLLLARVGGP +AMLTRFWRSLGDAQTRLDDWEPVLNRTPPGGLRNTTTPRAMAGTLEHLLFGDTLSVSSRT +LLTDWLKGCRTGAHRLRAGLPEGWGVGDKTGNNGRDAVSDIAVAWAAPQRPIILSVYTRG +GHPVEEQFRTAFAGIGRMV---- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. P44RR-XXIV TaxID=1921145 RepID=A0A4T3FLA5_9RHIZ +---IAARFKKLEKRSGGRLGVAVLNTATGQLA-GNRLDERFAMCSTFKALAVAFTLSRVD +RGQEQLDRRIFFKEGDLVTPFKATKPHLADGMTIEQLCEAALIVSDSTAANLLLASFGGP +AALTGYLRSLGDPVTRLDRIELDLNIVKPGETHDTTSPRAMVATLQKIILGDALSAASRA +KLTNWMIASKDAAQRLRVGLPNGWRIANKPGTWNGISTNDIGVIFPPGRDPIVVAAYLGE +APGSIKDHEAILAEVARIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=A0A2G4ATK0_VIBSP +-----QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE +NEGLDLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP +NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TELTIQERDTVINEIGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. D-99 TaxID=2717316 RepID=UPI00141F896A +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARTSGDMTFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLHEPQRA +QLTEWMAGGARGATGIAAGVPPGWRIAGKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ +PQAAAAARADVVASAARIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Lechevalieria fradiae TaxID=200378 RepID=UPI000B7CC2DA +----TGRLRELERRHGARLGVFALDTGSGRTV-LHRADELFPMCSTFKTLAAAAVLRRDV +-DGSLLGKVITYTQAEADKYAPITGANLANGMTVSALCEATITYSDNCAANLLLRELGGP +TAISRFARSIGDPVTRLDRYEPELNSAEPGRRTDTTSPRAIGQSYARLTLGHALDRPDAE +QLTNWLLANTTGGNRVRAGLPAEWGWGDKTGGGSYGTTNDVGIAFPPGRAPIVIATLSTR +ESPDGGADEPLLVKTAQLLAETf +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio kanaloae TaxID=170673 RepID=UPI0010BD45F7 +------SIAKIESRISARIGVAVYDSATGQIW-NYKGDERFPMMSTFKTLTCANLLYDHE +SEGLDLESKVGIEPDELIAWSPITKSFVGKEISLRSACAATMEMSDNTAANIVLRSTGGP +NGLTEFLRFMGDRKTRLDHIEPDLNHARPGDQRDTATPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TELTIPERDTVINEIGELVFDEy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WXJ0_9BACT +-----AAAQATEKALGARVGVAVIDMADGASW-TYKARERFPMASTFKGLACGALLAAGA +---DVKARSVVIQKQELVPYSPVTETLVGKEVAAVDLCKATLRTSDNTAANKVLDILGGP +AKVTAFLRESGDDITRLDRREPELNEGKPGDDRDTTTPLAVATTMRNLILGDILKESDRA +QLTEWLVANEVGGPLLRAGVPSDWRIADRTGGGGFGTRGVVAVMWPAQGEPIVAAVYITE +TTATMDERNKAIAEIGRAIAT-- +>[subseq from] Class A beta-lactamase n=1 Tax=Alcaligenes aquatilis TaxID=323284 RepID=A0A427M0A2_9BURK +-----QAAQEAEQSLQARIGLAVLDTADGQLW-QYRADERFPMASTSKALICSALLARGP +---GAMKTAWLIKEEAIQSDAPTTENLIGHYVSAAQLCAITMRNSDNTAANGVLEMLGGP +QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDALKTPDRD +RLTDWLRHNEVGGPLLRAGVPESWTVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE +TKASMEARNAAIAAIGKVIAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Kibdelosporangium sp. MJ126-NF4 TaxID=703222 RepID=A0A0K3BE76_9PSEU +--AVTTDFTALETRFGARLGLVAVDVTSGKAV-AHRENETFALLSVFKGYAAGALLKAHP +LDTGFFNQTIKYTKADLVDNSPVTEKHVDTGMTVAAICEAAITRSDNTAGNLMLKLLGGP +TKLTEFARSVGDPKTRLDRWETDLNVVPPGTEQDTTSPAAIGNAYRSLVVGDTLGVPERT +QLKNWLLASTTGAERIRAGLPSGWVTGDKTGTGGWGTANDVAVTWPSPDKPIVIAILTDK +KAKEAKPDNALLAEATRIAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis prasina TaxID=2015 RepID=UPI0005940F17 +--DFEAEFEALEEEFDARLGVYALDTGSGEEV-AFQEGERFAFASTFKALLAGVVLSGNS +--LEEMERVVTFDESVLVPHSPVVEEHLESGMSLLELCDATVRFSDNAAANLLLEEIGGP +EGFGSALEETGDDVTNPVRWEPDLNEAVPGDERDTSTPEALAGSLEAFTLGEVLPEDRRE +VLVDLLVRNTTGDDLIRAGVPEGWVVGDKTGGGGHGTRNDIAVLWPEEGDPILLAVLSSR +DVEDAEYDDALVAEATEVVVE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. WL3 TaxID=2603277 RepID=A0A5B9FMS7_9RHIZ +--TMTAAAQAVETRLGMRVGFAVINTGGGETL-TYRADERFAMASTFKALACASALAGGQ +---AVLDKETRITKADLRPHSPVTEKRVGTSLSTRMLCEITLRTSDNAAANAVLAAIGGP +PALTTFLKGIGDGTTRLDRYEPELNQATPGDPRDTTTPKAMAETLRRLLLDDALEPGARD +QLEAWMAANAVAGGLLRAELPAGWTIADRSGAGGHGTRGVIALLRPPEGPPLVVAIYMDG +RKHPLKVRDAAIAEIGKAIFAEy +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI00080EBF31 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTTITKEQIMPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSKTLNALLFGNTLNPQDKQ +TLKSWMMNNRVSDPLLRSILPSDWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFNEf +>[subseq from] Beta-lactamase CTX-M-1 n=2 Tax=Legionella israelensis TaxID=454 RepID=A0A0W0VTP8_9GAMM +--ALKKKLAELESQSGGRIGLYAINTADNSHI-QYRANERFPTGCTSKVMGVAAVLQKSM +SEPLLLQKKLFYKQEELTNWNPVTEKHLSDGMTVEALCAAAISYSDNTAMNLLVKQLGGV +QVMNIFARSIGDTVFRQDHGWPEAMSGGLDNVNDSSTPKAMAKSLQRLALGHILAESQRQ +LLISWLQQNTTGEARIRAGVPKGWIVGDKTGTGMYGTTNDIAIIWPPKSAPIVLVVYFTN +DHKTAEKQESVIAQATKLVINAf +>[subseq from] Beta-lactamase n=1 Tax=Cryobacterium sp. Sr59 TaxID=1259202 RepID=A0A4R9BYE7_9MICO +-----AEFTTLEATYDARLGVYALDTGTGSEI-SWRDDERFAYASTIKAMAAAALLDTVG +--LAGLATPVPIEESDIVPYSPVTEPRVGGSMTLGEIAHAAMTVSDNTAANLMFEALDGP +TALDVDLSNLGDDTTVVSRIEPDLNEAVPGDDRDTTTPRAFATNLNEYLFGEHLSGGEKA +QLETWLTGTQTGDTLVRADLPTDWVVGDKSGSGGYGTRNDLALIRPPGRAPIIISVMSSK +AEPDAESDDRLIAEAAAAAM--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium elephantis TaxID=81858 RepID=UPI000629BC92 +--TVEAQIAALEVQHGALIGVYASNLDLQRTV-AHRAQERFAMCSTFKTYAAGRTLQMAE +RGELSLEQSLFVDPEDILINSPITEARAGGELTLAELCQAALQRSDNTAANMLLATLGGP +QAITAFARSIGDSESRLDRWETALNSAIPGDPRDTSTPQALGFGYRNLLAGDALAPPERS +RLEDWMRANQT--SSMRAGLPDGWTSADKTGGGDYGSTNDVGIAYGPDGQRVLLALMTRS +QTADAPGLRPLIGELTSLV---- +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI0009C0D612 +----VQTAQMLEQSLGARVGLAVLDTADGHVW-QYRANERFPMASTSKLVICAALLARGP +---GAMKAAWRVRQEAVQSYAPTTKDRVGEQISADQLCAITMRNSDNTAANGVLEILGGP +AAVTSFLRSVGDTVTRLDRNEPSLNEAAPGDPRDTTSPYAMVQTLHRLALGDALKAAGRD +QLIGWLRRNEVGGPLLRAGVPERWAVAGRTGAAAYGTRGVVAVMWPPERAPLVAAVYITE +TQASMDERNAAIATIGKAIA--- +>[subseq from] Uncharacterized protein n=1 Tax=Enterovibrio pacificus TaxID=1080227 RepID=A0A1C3EMT1_9GAMM +---LSDTIKKVEQQTKGRVGVAVWDSRDNSWW-NYRGSERFPMMSTFKTLLCAKALHDIE +SGSLSSDASERIESKNLIPWSPITEQRVGQSMTVIEACEATMLTSDNTAANLALNLTGGP +SALTAFLIKQSDSTTNLTRFEPDLNTAIPGENRDTTSPEAMLRTLQKILLGNALTRKHRA +QILMWMKNNRVSDPLLRSVLPAGWQIADRSGAGGYGSRGVTALVWPNSDRKLMVSIYLTE +TKLDLTKRNKVLAEIGKAVFSNy +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. THAF192 TaxID=2587868 RepID=A0A5P8ZQN0_9MYCO +-----PRIEALERREGVIVGLHAVDLPTGRRL-AHRAKDRFAMCSTFKGYAAAAVLSRVD +RGLLALTDTVTIAPAELVTYSPVTEPRVGQPMTLAELCQAAVQQSDNSAANALLRVLGGP +PAITEFARSIGDEVTRLDRWETALNSAVPGDLRDTSTPVALGTGYRALLAGDALAGSSRQ +TLQDWMRANET--SSMRAGLP-GWTTADKTGSGDFGTANDVGIAYGPQGQQLLLSIMTRS +AGPEAPSRRDLIGELAALVA--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. 17J27-24 TaxID=2555898 RepID=A0A4Y8ZX04_9SPHN +-----AALEAIRATLGARLGVAAIDTATGSRL-LFDADSRYAMCSTFKAPLAAAILSAAE +RGTLSLDEEIAFGPADLLDHAPVVRANLAKPLPVRTLCAAIVEVSDNSAANLLLARIGGP +AGLTRFVRAAGDSVTRLDRTEPELNSNLPGDPRDTTSPAAFAALIQRLVLGDVLRPASRD +LLAGWLRSASTGLDRLRAGLPQGWTAGDKTGTGN-GANNDVAVAWRPDGSALVIASFTNG +DA-PAGVRNAAHAEVARLVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. AC27/96 TaxID=1841653 RepID=A0A1B9RYW7_9RHIZ +---IAARLKKLEKRSGGRLGVAVLNTATGQLA-GNRLDERFAMCSTFKALAVAFTLSRVD +RGQEQLDRRIFFKEGDLVTPFKATKPHLADGMTIEQLCEAALIVSDSTAANLLLASFGGP +AALTDYLRSLGDPVTRLDRIELDLNIVKPGEIHDTTSPRAMVATLQKIILGDALSPPSRT +KLTNWMIASTDAAQRLRVGLPNGWRIANKPGTWNGISTNDIGVIFPPGRDPIVVAAYLGA +APGSIKDQEAILAEVARIVAE-- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia multivorans TaxID=87883 RepID=B9AZR0_9BURK +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLTEWMTAGAR-GDGIAAAVPPGWRAAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Atlantibacter hermannii TaxID=565 RepID=UPI001377FBAA +--AMTQFLQQQEKRLNARIGMAVVNAQGEPVF-GYRQDERFPLTSTFKPLACAALLARLQ +KDGGSLDQQVTIQPDELLDYAPITKNYLAPSLSLRMLCAAAVSYSDNTAGNRILTYLGGP +GAITSFMRRLGDNVTRLDRTEPALNEATPGDARDTSSPKSMALGLQKMLTSNTLTPTNRA +TLAGWMREDKVGDALLRATLPPGWAIADKTGAGGHGSRAIIAAVYPPQQAPFYVAIYLTR +TEATMEMANTAIAQIGERLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI000A37856D +--AADAAFAALEERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--VAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEGLGGP +TELDAALTALGDDTTVVSRTEPDLNEAIPGDERDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPAEWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSAK +DQQDAKADDALISGAAKAAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFE7B27 +--SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVPWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARSVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A251Y7K2_9MICO +--AADAAFAALEERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--VAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEGLGGP +TELDAALTALGDDTTVVSRTEPDLNEAIPGDERDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPAEWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSAK +DQQDAKADDALISGAAKAAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio sinensis TaxID=2302434 RepID=UPI0014023836 +--QAEKAIKMQEETLSARIGVAVLNVESGALY-SFRGDERFPLTSTFKSIACAKLLYDVD +QERNELSQTVTVSSDDLVTYSPILEAYAEKEITLGDSCQATMLTSDNTAANIIIESVGGT +ESITSFLRDIGDMNTRLDRVEPELNEALPHDLRDTTTPISMTKTLSELLFGPVLSQDSRV +QLIDWMKRNEVTGNLLRSALPSGWEIGDRSGAGGFGSRSITAVVWRDKQSPLIVSIYVSQ +TDASMDQRNLAIVEIGKSIFDLf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas japonica TaxID=511662 RepID=UPI00111D25E7 +---ARDALRDIARASGGRLGVFAYDTGTGRRL-SLDAGARYALCSTFKAPLAAAILAQVD +AGRLTLDRTIRFGEADLLGYAPVVRENLATGLSVERLCRAAVEVSDNSAANLLLPQLGGP +AGLTRWLRSIGDPATRLDRDEPTLNIVRGGDLRDTTTPMAIAMTIDRLLFGDVLMPQSHA +LLQRWMAASTTGRARLRGGLPADWQCGDKTGTSGEGCFNDVAFAIPPGRKPIVIACYLDA +AGLSDANANAAHAAVGELVGQVf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0013DF1AC6 +--SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTIFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRAAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIASAARIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X2C3_9BACT +--------ENIEERLDARVGLLIRDSGTGWSW-GHRADERFLMNSTAKVPLCGAVLAQVD +KGAMRLTDGLDVRAEDMVEYAPVTELRIGDTMQVGELCFAALDMSDNAAANILIDHLGGP +QEVTAFMRQIGDDVSRLDRREPDLNRFETGDPRDTTSPAAVVDTPERLLVGDALSPSSRA +QLTEWMTPGGVTGALLRAFTPDSWRVADKSGSGSV-TRNIVGMIAPPQGGPYFVAIYLSE +AEADFDTRNAAVVAISAAVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis subsp. capsici TaxID=1874630 RepID=A0A0M4HV79_9MICO +--AADAAFAALEERFGARLGVHAVDTGSGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMERAVPIEAADILSYAPVTETRVGGTMTLRELADAAMTRSDNTAANLLLEALGGP +AELDAALAALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAAYLRAYALGDPLDADERA +LFTGWLKATQTGGTLVRAELPADWTVGDKSGSGAYASRGDIAVIWRPDAAPLVIAVHSSK +DQQDADADDALISGAAKAAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000D007B51 +----RSELAALDKASNVRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP +QAVTAFAHESGDTVFRLDRWEPELNRATPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA +QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ +AQADAAARADVVASAARIAT--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio sinensis TaxID=2302434 RepID=A0A3A6R2Y4_9VIBR +--QAEKAIKMQEETLSARIGVAVLNVESGALY-SFRGDERFPLTSTFKSIACAKLLYDVD +QERNELSQTVTVSSDDLVTYSPILEAYAEKEITLGDSCQATMLTSDNTAANIIIESVGGT +ESITSFLRDIGDMNTRLDRVEPELNEALPHDLRDTTTPISMTKTLSELLFGPVLSQDSRV +QLIDWMKRNEVTGNLLRSALPSGWEIGDRSGAGGFGSRSITAVVWRDKQSPLIVSIYVSQ +TDASMDQRNLAIVEIGKSIFDLf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3L0W1F9_ECOLX +------KVNSYEN-QGWSIGVTVFDTKSGKRE-SVHGEKRFHFNSTIKALACANVLAKVD +KGQLALDDFIELKKKDIVTYSPVTEKLIGKKLTLRDACEATLTYSDNTAANYAISSVGGP +DGLTAFMRSIGDNALRSDRYEPDLTKNIEYDIRDTTTTDAMAQSLYRILLQDVLSEKSRT +QLKKWMEGNKVADDLLRASLPDGWFIADRSGASDYGVRGIISIVWSENRQPLVIAMYVRK +DGSSMSERDKVISDIGATIFSSy +>[subseq from] class A beta-lactamase n=2 Tax=Legionella israelensis TaxID=454 RepID=UPI001072CD31 +--ALKKKLAELESQSGGRIGLYAINTADNSYI-QYRANERFPTGCTSKVMGVAAVLQKSM +SEPLLLQKKLFYKQEELTNWNPVTEKHLRDGMTVEALCAAAISYSDNTAMNLLVKQLGGV +QVMNIFARSIGDTVFRQDHWSQEAMSGGLDNVNDSSTPKAMAKSLQRLALGHILAESQRQ +LLISWLQQNTTGEARIRAGVPKGWIVGDKTGTGMYGTTNDIAIIWPPKSAPIVLVVYFTN +DHKTAEKQESVIAQATKLVINAf +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio chagasii TaxID=170679 RepID=UPI0010CA9497 +-----ESIEQIESRVSARIGVAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDAE +NKGLDLDSKVSIKSEDLIVWSPVTKELVDKGISLRDACSATMTMSDNTAANIVLGGIDGP +NGLTEFLRSIGDSNTRLEHLEPELNHARPDDARDTTTPKSIVMTLNELMYGDTLSQASKS +TLKGWMMGNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWSEHRDPLIISVALTE +TEFTLQERDKVINEVGQLIFDTy +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI001366628E +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADILSYAPVAETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDAAPIVIAVHSSK +DQQDAKADDALISGAAKAAAQ-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Clavibacter michiganensis subsp. chilensis TaxID=1523530 RepID=A0A399TAD1_9MICO +--AADAAFAALEERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRAEPDLNQAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPADWTVGDKSGLGAYASRGDVAVIWRPDAAPIVIAIHSSK +DQQDADADDALISGAAKAAVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Kineococcus rhizosphaerae TaxID=559628 RepID=UPI0011B2517F +--AVQARFAQLEESFDARLGVFAVDTGSGRTV-VHRGDERFGFASTYKALAAGALLERTG +--DAELDAVVTWTADEVVAHSPVTGQHTASGLPLRQVAEAAVTVSDNTAANVVLAHLGGP +AGLEEDLRALGDDTTEVEHTEPDVNDITPGDPADTSTPRAMATTLQAYATGDVLAPAGRD +QLVRWLQAGTTGGGQIRAGVPAGWVVGDKTGHAGYGNQNDIGVVWPTGGAPWVLAILTDR +ADVDATSDEALLARATEVVVDE- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fluoranthenivorans TaxID=258505 RepID=UPI0014240298 +---LDQQIGALERRHNAVVGLSAVNLNSPGTV-AHRPDQMFAMCSTFKAYAAGRVLEQVG +RGELSLEATEFVDPSAVVANSPVTGPRAGSQMTLAELCQAALQRSDNTAANLLLRRLGGP +PAITAFARSVGDDRTRLDRWETELNSAIPGDPRDTSTPAALAGGYRALLTGDVLAPPQRL +LLEQWMRANQT--SSMRAGLPTGWTTADKTGSGDYGSTNDVGVAFGPEGQRVLLAIMTRS +AADDADALRPLIGELTTL----- +>[subseq from] Beta-lactamase n=1 Tax=Atlantibacter hermannii TaxID=565 RepID=Q84EY1_ATLHE +---MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ +KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP +DAVTQFMRGIGDPVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTAPPLTPANRA +VLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ +TEASMKMANEAIPAIGKQLF--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. AcH 505 TaxID=352211 RepID=A0A0C2ANI9_9ACTN +--TLTEQFRALEQEYAARLGVFALDTASGATV-GYRAQERFPMCSVFKGLAAAAVLRDVD +RHGEFLARRIRYTAEFVEAYIPVTGKNIAHGLTGAELCAAAVSESDNGAGNLLLRELGGP +TAITRFCRSLGDGTTRLDRWEPELNSAEPWRIEDTTNPRAVGMTYGRLLLGGALSPGDRK +RLWEWLVANTTNTERFREGLPADWILADKTGGGEYGVANDVGVVRPPGRSPLVLSILSTK +YDPQGPTDNPLVARAAAIVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycetocola saprophilus TaxID=76636 RepID=UPI00068F6A5A +---------------------FLIDTGAQRTV-EYRADERFAFASTIKAHQAAAILQTRE +--IAALQEHVTFTAEQIVSYSPITEQHFEDGMLLHEVVTAALQYSDNTAANLMFDRLGGP +SGLQQLLRESGDHTINVDRIEPDLNEATPGDPRDTTTPRAHAHTLARFGISDHLPAEKRE +LLTGWMKANTTGGELIRAGVPADWVVADKTGGGYYGTRNDIAILWPPTGAPLVLAVMSSK +DAQDAEYSNALIARATTQA---- +>[subseq from] Beta-lactamase n=1 Tax=Rhodopseudomonas palustris (strain BisA53) TaxID=316055 RepID=Q07QH1_RHOP5 +----PSALQTYERESGGRIGLYAENLATGTKI-AWRADERRVMCSTFKASLAALVLARVD +RGEDRLDDIISYSAADLLDYAPVARENLAKGISVDEMCKAMVEFSDNTFANLLLARVGGP +AALTGFWRATGDSISRLDHNEPELNFPPPGDPSNSTTPIAMAGTLRRVVLGEVLTPASRD +RLIGWMVNCKTGANRLRAGLPTDWKIADKTGNNGVDAAGDIAVAWPRANAAVVICAYTQG +GTPTKAQLETVFAAIGRMVG--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium chlorophenolicum TaxID=37916 RepID=A0A0J6YBQ7_9MYCO +------DLTAVEDRTGARIGLYAMELGSGAAL-AHRAAERFAMCSTFKTYAVARVMQLAE +SGHQPLDASLPVVDADIVENSPVTSARVGGSMTVEEVCAAALIRSDNTAGNLLLRRIGGP +PAITAFARSVGDNESRLDRWETELNTALPGDLRDTTTARALASGYREVLTGSALTDAARN +RMLGWMAANETSQKRFRAGLPGGWTSADKTGAGDFGSTNDAGLLIGPEGQRIAIAVLTRS +RDPDAEPFNDAIAEAVRLAIARf +>[subseq from] Beta-lactamase n=3 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A1C8JYW2_PROMI +-----NSIKEVEQNLGAKVGVSIYSVSDGYLW-HYNGDSRFPLMSTFKTLACAKLLHDVE +TAKLSIDRSVKIEEQDLITWSPITEKLVGESFSLKQACTAAMVMSDNTAANIVLDGISGP +SELTLFMKELGDEVTRLDRIEPHLNEARSGDERDTTTPNAIVKSLGKLLYGEKLSSGSKE +QLIEWMAGNKVSDSLLRSVLPEGWSIADRSGAGGFGSRGITAAIWSNEQQPLIVAIYLTQ +TEASFDERNKAIAKIGREIFASy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces virginiae TaxID=1961 RepID=A0A2D1BXP5_STRVG +-----RRLRDMEREHGARIGAYARNLATGRTV-AHRAEELFPVCSVFKPLAAAAVLRDLD +HDGEFLARRVHYTAAEVDAWTPVTQDHVADGMTVEALCAAAVSQSDNLAGNLLLRELGGP +TAITRFARSLGDRVTRLDRWEPALNSAEPWRTEDTTNPRAIGETYARLLLGDVLPRGDRD +RLTGWLLANTTNTHRFKEGLP-GWTLADKTGGGDYGVANDVGVVWSPAGVPVVMAVLTTR +PQAPGPNDSELVAETARLL---- +>[subseq from] Beta-lactamase n=1 Tax=Actinobacteria bacterium OV320 TaxID=1592329 RepID=A0A0N1GYN8_9ACTN +---------------------FAYNVRTGRSV-RYRAAERFPVCSLFKTLAVAAVLRDLP +--EGTLDRRVFWTSTDVVENSPVTQDHVADGMTIAELSAAAIQRSDNTAGNLLLRELGGP +TAITRFARSVGDRVTRLDRWEPDLNSAEPDRVTDTTTPYAIGRTYARLVLGDALAPADRR +RLTDWMLGTITSANRFRAGLPPTWTIADKTGGGWYGANNDAGIAWTPDGAPVVLAVQLTK +PDREAAYDNELIVKTAEVLAE-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Ralstonia TaxID=209769 RepID=A0A100I051_9RALS +---LQQATQREEEALNARIGVAVIDKESGMTW-SYRGDEAFPINSTHKAYLCAALLEKVD +QKQLALSDRTTLSKRDLVAYSPITETLLPPQASNAQLCEAAVSYSDNTAANKVLETIGGV +EGFNGFMRSIGDQKTRLDRKEPELNEGTPGDPRDTTTPVAAVRSLDQIFFSDHLSRSSKS +ELKTWMVNDKVAADLLRKSLPAGWDIADKTGAGGYGSRSIVAVVYPRGKKPLLVSIYITQ +TKATLGESNAAIARMGAILFK-- +>[subseq from] class A beta-lactamase n=1 Tax=Microtetraspora niveoalba TaxID=46175 RepID=UPI000A06B2C0 +--KVRKDLRKLEASFKGRIGAYALDTSTGKTV-TYRAGERFPLLSTFKAPLCAAVLHKAR +TKPGLMDTVVKWTAADMKPNSPVTEKHIKDGLTVAQLCEAAMTQSDGTASNLLLKQIGGP +AGLTRYFRTLNDRTSRMDRWHPGLNNWAPGEKRDTTTPAAIGRDLRALTTGTALHAKDRQ +QLITWLLANKVGGERIRAGLPTTWTIGDRTGTNSFGGGNDIAVIWPAKGAPVIMAIYTNR +TP-GLATDNRTIAKTAAILA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SA88_KLEPN +---------RLERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYG------------------------ +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Salmonella enterica I TaxID=59201 RepID=A0A3U9Q9E2_SALET +--SIDDTVKQVETTLGAKVGIAVLDTGSQRAW-FHRADDRFPMASTSKALTCAALLDK-- +-GQSFMNKEALIKKADLDEYAPVTSGIVGKKVSAADLCSITMRTSDNTAVNKVLEILGGP +QAVTAYLRKTGDNITRLDRNEPDLNEGTPGDVRDTTTPRAILETLNKLVLGPTLGSDERK +QLTTWLESNEVGDPLLRAGVPSDWRVADRTGAGGDGTRGVIAVMWPPKHAPIIAAIYITQ +TKATMEERNAAIASIGKAIAA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Legionella israelensis TaxID=454 RepID=A0A516MY49_9GAMM +--ALKKKLAELESQSGGRIGLYAINTADNSYI-QYRANERFPTGCTSKVMGVAAVLQKSM +SEPLLLQKKLFYKQEELTSWNPVTEKHLSDGMTVEALCAAAISYSDNTAMNLLVKQLGGV +QVMNIFARSIGDTVFRQDHGWPEAMSGGLDNVNDSSTPKAMAKSLQRLALGHILAESQRQ +LLISWLQQNTTGEARIRAGVPKGWIVGDKTGTGMYGTTNDIAIIWPPKSAPIVLVVYFTN +DHKTAEKQESVIAQATKLVINAf +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium marinum TaxID=1781 RepID=UPI000E3DC896 +--DLESRFAELEQKYEARLGVYVPGTDATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP +--IAHLGTVITYNSADIRSTSPITEQHLATGMSIGGLCDATIRYSDGTAANLLLQDIGGI +AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHTIAMDYQQVVLGDALLPEKRD +KLIDWLGRSTTGAKRIRAGFPADWRVIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR +VGPEAPWCDPLVADAAKCVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Arthrobacter sp. MDT2-14 TaxID=1258920 RepID=A0A3A5NI64_9MICC +-kDLVAALRNLETRYDARIGVFAKEGLDGKSF-AWRADERFAYASTYKALAAGALLDKFG +--TDILDTTVQIPEGDLVEYSPVTEQYAGQEMTVRQVAEAAVRTSDNTAGNILLELLGGP +HGFDEELEHLGDTTTRADRFEPELNEATPGDPRDTSTPAALAQDLQAYVAGDELSTEERA +LLTKWMSANATGDTLVRAAVPEDWIVIDKSGAGRFATRNDIAIVTPPDEPPVTIAILTSR +SAEDATRDDDLVVDTARLVLE-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI000E32503B +-----ESIEQIESRVSARIGVAVYDSATKKAW-SYKGDERFPMMSTFKTLACANLLYDAE +NKGLDLDSKVNIKSEDLIVWSPVTKELVGKGISLRDACSATMTMSDNTAANIVLGGIDGP +NGLTQFLRSIRDSNTRLDHLEPELNHARPGDARDTTTPNSIVMTLNELMYGDTLSQASKA +TLKGWMMDNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWSEHRAPLIISVSLTE +TEFTLQQRDKVINEVGQLIFDTy +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. WL64 TaxID=2603894 RepID=A0A5C8T7G6_9RHIZ +--ETAPTLAEIERRLGGRLGVSAG-TRDRVLL-SHRADELFPMCSTFKAVAVAAILARVD +AGSESLDRVVDFGPDILLSYAPVTRKVVEAGMSISDLCAAAIVWSDNSAANLLLTALGGP +EALTVWLRGTGDTRTRLDRDEPTLNTALPGDPRDTTSPEAMRQTLGRVLLGPVLSAASRG +RLEAWMIACQTGAKRLRAGLPPDWIVGDKTGSGDNGTFNDVAILRPPGSAPVLACVYVTG +ATAPAPAVESAYAEIGRLIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI0014284421 +--AADAAFAALEERFGARLGVHAVDTGTGTEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMERAVPIEAADILSYAPVTETRVGGTMTLRELADAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAAYLRAYALGDPLDADERA +LFTGWLKATQTGGTLVRAELPADWTVGDKSGSGAYASRGDIAVIWRPDAAPLVIAVHSSK +DQQDADADDALISGAAKAAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. WL1 TaxID=2603276 RepID=A0A5B9F9C9_9RHIZ +--ETAPTLAEIERRLGGRLGVSAG-TRDRVLL-SHRADELFPMCSTFKAVAVAAILARVD +AGSESLDRVVDFGPDILLSYAPVTRKVVEAGMSISDLCAAAIVWSDNSAANLLLTALGGP +KALTVWLRGTGDTRTRLDRDEPTLNTALPGDPRDTTSPEAMRQTLGRVLLGPVLSAASRG +RLEAWMIACQTGAKRLRAGLPPDWIVGDKTGSGDNGTFNDVAILRPPGSAPVLACVYVTG +ATAPAPAVESAYAEIGRLIA--- +>[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A2S5VUX3_9MICO +--AADAAFTALEERFDARLGVHLVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADVLSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTSLGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLQATQTGNTLVRAELPTEWTVGDKSGSGAYASRGDVAVVWRPDTAPLVIAIHSSR +DAQDAEPDDALISGAARAAVQ-- +>[subseq from] Beta-lactamase n=2 Tax=Enterovibrio norvegicus TaxID=188144 RepID=A0A1I5NMS1_9GAMM +-----------EETLSARIGVAVLNVESGALY-SFRGDERFPLTSTFKSIACAKLLYDVD +QKRTELNNTVAVNSDDLVTYSPILEAYVEKEITLGDSCQATMLTSDNTAANIVIESVGGT +ESITSFLRDIGDVNTRLDRVEPELNEALPGDPRDTTTPISMTNTLNKLLFGTVLSQDSRV +QLIDWMKRNEVTGNLLRSALPSGWEIGDRSGAGGFGARSITAVVWRDKQSPLIVSIYVSQ +TDASMDQRNLAIVEIGKSIFDLf +>[subseq from] Beta-lactamase Toho-1 n=2 Tax=Legionella feeleii TaxID=453 RepID=A0A0W0TUA4_9GAMM +---IQEKLAKLEASSGGKIGIYAINTANGQKI-HYRANQRFPMGCTSKVMGVAAILKKSM +SDPTLLSQRISYTKKDLTNWAPIAEKHLNTGMTVAELCAASISYSDNTAMNLLVKKLGGL +EKINDFARSIHNDTFRQDNGWPEAMSGGPNNVYDSSTPKAMAQSLQQLALNNVLAKPQHE +LLLSWLKSNTTGDKRIRAGVPKGWIVGDKTGTGMYGTTNDIGVIWPPQCSPVVIAVYYTN +NNKEAIQRNDIVSSATRLVIDGf +>[subseq from] Beta-lactamase n=1 Tax=Rhodobacterales bacterium TaxID=1948890 RepID=A0A2G6IKV1_9RHOB +--DTRAELESIEQRLSARIGVYAENLRTGQAF-EHRPDERFAMCSTFKASLAALCLSRSD +QGQLDLDERLAFGGTEILPTSPVTQNNLAAGMSISDLCQAIIEYSDNTAANLLLTHIGGP +AAMTQFFRDIGDTTSRLDRVELALNSNTEGDERDTTSPRAMARTLSQLTMANVLSDQSRA +RLIQWMRNEQNGRNRIRAAVSGDWTVGNKPGTSSNGAANDIAVLWSPDGIPFVVTVFIDA +ERGRTREAVGSIREVAGLALD-- +>[subseq from] Beta-lactamase n=1 Tax=Microlunatus soli TaxID=630515 RepID=A0A1H1WXJ7_9ACTN +------DLARLEATYRTRLGVYAFNVRTGRTL-CHRPNERFPIASVFKTLAAAAILRDHD +RHGEVLASRRYWTAEEVVDASPVTEKHVADGLTVAELCEAAITQSDNTAANEMLKIIGGP +RGLTRFARSIGDRATRLDRWETELNSAIPGDLRDTTTPQAIAASYAELALGHVLIRRDRH +QLLDWLLHNQTSAERFGAGVPDGWPLADKTGSPAYGGLNDVGITWTPAGTPIVMAGLSVT +DRPDAVIDPALMADVARLCC--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium attenuatum TaxID=2341086 RepID=UPI000F03A102 +-----KQLEELEHTFDGKIGVYAINTSNGEII-AHREDERFPLQSTIKFMGVAALLKQSD +TDSHLLQEIVHYSQNDLIEWSPITRKNITGGMTLEALSEAAISYSDNAAINIIMKRLGGP +PAVAQFAHSVGNQTYNVEHYDGALNSD-PTSGADTSTPRDMAASVQKLSLGDGLTPAQQT +QLLGWMRNNTAGYRRIRAGVPGGWVVADKTGSGDYGIANDIGILWSPYCKPIVLAIYTVQ +NQRDAKRREDIVASATSIVLDQf +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A3B9YWT8_9PROT +----QTRFKVIEASAGGRLGVAILDLAFGATI-GTRLNERFALCSTFKLPLAAAVLEAAD +KGQLSLDEIIPYTKADLVFHAPVTGPNLAKGLTIRALAEAAQLTSDNVAANLLIKRLGGP +QAVTAIWRRWGDPATRIDRYEPEMNLVKAGDVQDTTTPEAIAMMVAKLCTEDVLKPASRE +MLIDWMIRTQTGLKRLRAGFPKQWRAGDKTGTMNGNKVNDVAIVWPPRRAPVIVAAFYES +PYDTRDQDQAILAQVGRIAAD-- +>[subseq from] Beta-lactamase n=2 Tax=Mycobacterium shigaense TaxID=722731 RepID=A0A2S9R1J6_9MYCO +----DDRLGEWERRYNAYVGLFATDIASGRTC-AHRADDPFAMCSTFKAYTAACVLQKAQ +RGELELQQPVFIDPSGLLPYSPVTAPHAGSTLPLAQLCAAALQRSDNVAANLLLREIGGP +QAITDFARSVGDDRTRLDRWEPDLNSAIPGDLRDTSTPRALGGGIQKLLTGTVLDDAHRS +QLEDWMRGNVT--STMRAGLPAGWTTADKTGTGSYGSTNDVGIAYGPAGQRVLLSLMTRS +ASPDADGLGPLIADVTAAVL--- +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium PA1 TaxID=2015569 RepID=A0A257HN71_9PROT +---PTAELAALEAKSQGRLGVGILDTASGELV-GHRQDERFALCSTFKLPLAAEVLRDVD +AGKRTLDQFIPYSKPDMVAHAPVTEANLAAGMAIGELAKATQITSDNPAANLILREFGGP +EAMTQRIRAAGDPVTRIDRYEPMMNRVVGDDPRDTTSPAAMARLVARYLTTDYLSQASRD +LLIGWMIETHTGTKRLRAGLPVDWKAGDKTGTAMTDKYNDVAIVWPPGRAPLIIAAYFNT +NIDMRDEFQAVLAEAGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Ralstonia insidiosa TaxID=190721 RepID=UPI000CEDBC3A +---LQQATQREEEALNARIGVAVIDKESGMTW-SYRGDEAFPINSTHKAYLCAALLEKVD +QKQLALSDRTTLSKRDLVAYSPITETLLPPQASNAQLCEAAVSYSDNTAANKVLEKIGGV +DGFNGFMRSIGDQKTRLDRKEPELNEGTPGDPRDTTTPVAAVRSLDQIFFSDHLSRSSKS +ELKTWMVNDKVAADLLRKSLPAGWDIADKTGAGGYGSRSIVAVVYPRGKKPLLVSIYITQ +TKATLGESNAAIARMGAILFK-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A2Z2Z5Q0_9BACT +--DLDQTIEALENRLDARIGVAIHDTGTGKVW-GHREDERFLMNSTIKVPLCAAVLSRSD +---VDLSEELPVRAEDILEYAPVTEQHVGGTMTVADLCFATIDQSDNTAANLLFGRLGGP +ESLTTFLRSIGDDLTRSDRLEPDLNIWSAGDPRDTTTPAAMVRTLEAMLTGDALTATARE +QLADWMRPGGVTGALMRPSVPHNWDVADKSGSGSN-TRNLIAMLTPPDGAPIFVSLSISE +AEVDFATRNAALVELSAAVVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus sp. Bac330 TaxID=2419841 RepID=UPI000EF48C00 +----ESEFRLLEKAYNAKLGIYAVDTSNGKTV-SYQAEDRFAYASTHKALAVGVLLQKLT +--LKQLKETVLIKEGDLVNYNPITENHVNKHMSWKELSDASIRYSDNTAANHILNRIGGP +NGFKKALRDIGDDVTNPERMEPELNLVNPGEIKDTSTPKALATSLKAFTMGNVLPKEKQD +LLVDWLKRNTTGDHLIRAGTPIGWEVGDKSGAAPYGVRNDIAIIWPPNKAPIILAILSSK +EGKNAEADDKLIAEATKKVI--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium celeriflavum TaxID=1249101 RepID=A0A1X0C3A2_9MYCO +----DARIGEFERQHNALIGVFAVNLDTGQTI-RHRAQEPFAMCSTFKGYAAARILQKAE +RDELALSDRVTIDQTDIVPNSPVTQTRVGQTMSLAELCEAALQRSDNAAGNLLLRAIGGP +PAITDFARSIGDQRSRLDRWEVELNAAVPGDPRDTTTPEAIGGGYRSMLTGAVLAEPQRR +QLEDWMRANQT--SSVRPALPPGWTTADKTGSGDYASTNDVGVAYGPDGRRLLLALMTRS +AGPNAPNMRPLIGELAALLV--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium arabiense TaxID=1286181 RepID=UPI00138B9E5C +--SIEDRIGALERQYGAFAGVYAENLDNGRSV-AHRADDAFAMCSTFKAYAAARVLQKAA +RGELNLTDAVTIEASDILPNSPITETRVGRNITIEELCVAAVQRSDNAAANWLLRVIGGP +SRITDFARSIGDDRSRLDRWEIELNSAVPGDPRDTSTPRALGGGFRSLLVGDALGEAERR +RLDDWMRANQT--SSMRAGLPQGWATADKTGSGDYATTNDVGIAYGPDGQRLLLAFMTRT +QSPDAPTLRPMVGELAALVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea sp. SBT364 TaxID=1580530 RepID=UPI00066C2DE3 +--QVAKELRKLEVSFKGRIGAYAIDTATGRTV-TYRAHERFAMLSTFKAPLCAAVLQRAR +TSRGLMGKVVKWTAADMKPNSPVTEKHLKDGLTVSQLCEAAVTQSDGTASNLLLKQIGGP +AGLTRYFRALKDSVSRMDRRHPELNDWTPKEKRDTTTPAAIAADLRALTTGNALHAKDRD +QLNAWLLASKTGAERIRAGLPRNWTIGDKTGTNSFGGGNDIAVIWPGKGAPIVMAIYTNR +TP-GLATDNRTIARTATALA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. USM B20 TaxID=1571773 RepID=A0A4V8GAK5_9BURK +---AQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTALLQAGDKGAGNLLMGVLGGP +QAVTSFAHESGDTAFRLDRWEPELNQAAPGDERDTSTPVAMVDMLQRLLLGDTLREPQRA +QLTEWMTGGAT---GIAAGVPPGWRSAGKTGTGGYGTTTDVAVLWPPSRAPIALAVSFTQ +PRADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=2 Tax=Corynebacteriales TaxID=85007 RepID=A0A448HUD6_MYCFV +---IEDRLGEMERRQNALIGVFATNLGTGRTI-AHRAQDPFAMCSTFKTYAAARVLQKAE +RGELALTDRITIEPGDIVPNSPVTEAHVGQTMTLAQLCQAALQRSDNAAGNWLLRVIGGP +SGVTDFARSIGDERSRLDRWEIELNAAVPGDPRDTTTPEAVGNGYRAILTGNELAEPQRR +QLEDWMRANQT--SSVRPVLPPGWATADKTGSGDFASTNDVGIAFGPAGERLLLAIMTRT +AAPDVPNDRQLVGEVASVLV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2DD60_STRVZ +--RVTTRLRQFEREHSARLGVYARNLATGRTV-AYREDELFPMCSVFKGVAAAAVLRELD +EDGEFLAQRIRYTAKYVEDYGPETGKDVNNGMTVEALCAASVSHSDNAAANLLLEELGGP +TAVTRFSRSIGDRVTRLDRYEPQLNSAEPGRVTDTTSPRAIGRTYARLILGDVLPARDRR +LLTGWLIANTTNTDRFRKGLPADWILADKTGGGQYGVANDVGVVWTPDGTPLVLAVLTTK +PGPTGPRDSELVRRTAELLA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=A0A1A6BI01_MYCGO +----DTELAALEERYNTSIGLFGLNTASQRAL-AFRADDMFATCSTFKAYVAAQILQQDQ +RGELRLTDTVYIDPAAAVPASPVTEPHIGGRMPLSELCAAAVRHSDNTATNLMLAMLGGP +ASVTAFARSVGDDRTSMVRWETELNTAYPGDPRDTTSPRAMGTGFLNMLTGDVLDAPHRA +QLQEWMRTIVTGDRRIRAGLPPGWSIADKTGSGDYASTNDIGVASGPHGERLVLAVMTRS +RSPNAVASETLIADVTRLAV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A345N7N5_VIBPH +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADQSG----------------------------- +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A3KEX8_STEMA +----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE +RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP +PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAV----------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia unamae TaxID=219649 RepID=UPI000D5D4DCC +----ESPFAAIERRSGGRLGVFAVDTGSGATL-AWRADERFLMCSTFKGMLAAQILARVD +AGHERLDREVRYTERDLIFTSPVTKANLAQGMTVGALCKAAVEVSDNTAAILLMRGAGGP +AALTRFMRDIGDDVTRSDRYEPASNQR--DGERDTTTPRAIVGSARKILLGDVLGAQSRQ +QLEDWMIASTPGRNRIRASLPPDWRAGDRPGTSVEGETNDYVIVRPPGRAPLVVATYYDA +PGLDMARREAVLREAGAAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=A0A2N7CAE4_VIBSP +-----ESIEQIESRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE +NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP +NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TQLTIQERDTVINEIGQLIFDAy +>[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea sp. WYY166 TaxID=2656914 RepID=A0A5P9Z0E7_9ACTN +--QARKELRALEKKFGGRIGAYAIDTATGKTI-AYRSVERFPLLSTFKAMACAAVLHKAR +TEPGLMDKVVHWTAGEVKPNSPTTSKHVKDGLTVSRLCEAAITLSDNTAGNMVLKQIGGP +AGLTRYFRTLKDPLSRLDRWETELNDWTPKDRRDTTTPAAIARDLRAVTVGSALDARDRR +RLNAWLRATETGDARIRAGLPKGWTVGDKTGSNSFGGGNDIAVVWPGKGAPIVMAVYTHR +AA-GQAGDDTAIARTATILA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium rhodesiae TaxID=36814 RepID=A0A1X0IXI9_MYCRH +-------LTPVEDRYSARVGMYALHLDSGASL-EHRADTRFAMCSTFKTYAVARVLQLAE +LGQRDLAETQPIAASDIVENSPVTSAHVGRSMRLDELCSAALINSDNAAGNLLLRCIGGP +PEITTFARSVGDDQSRLDRWETGLNSAAPGDPRDTTTPRALTTGYREVLTGRVLTERTRE +QMVGWMRQNATSTKRFRAGLPAGWTSADKTGAGSYGSTNDAGLLYGPRGQRIIMAVLTRS +RDPDAPPFNDAIADTVRLTLATf +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium lentiflavum TaxID=141349 RepID=A0A0E4GXB2_9MYCO +---VDGRLAELERQYDAYIGLFAADLGSGRTC-AHRDDDPFAMCSTFKAYAAARVLQKAQ +RGELDLQQLVFIDPAALLPNSPVTAPQAGNTMPVAQLCAAALQRSDNVAANLLLAQIGGP +PAITDFARSIGDTRTRLDRWEIELNTAIPGDPRDTSTPRALGNGVQKLLTGTVLGDAQRS +QLQRWMRDNVT--SSMRAGLPPGWTTADKTGTGDYGSTNDIGMVYGPAGQRLLLSLMTRS +RSANADALRPLIVEVTKSV---- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI00084C17D8 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTTITKEQIMPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +ALKSWMMNNKVSDPLLRSILPNNWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFNEf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SAB3_KLEPN +---------RLERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYG------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. AcH 505 TaxID=352211 RepID=UPI00099BD2AD +--TLTEQFRALEQEYAARLGVFALDTASGATV-GYRAQERFPMCSVFKGLAAAAVLRDVD +RHGEFLARRIRYTAEFVEAYIPVTGKNIAHGLTGAELCAAAVSESDNGAGNLLLRELGGP +TAITRFCRSLGDGTTRLDRWEPELNSAEPWRIEDTTNPRAVGMTYGRLLLGGALSPGDRK +RLWEWLVANTTNTERFREGLPADWILADKTGGGEYGVANDVGVVRPPGRSPLVLSILSTK +YDPQGPTDNPLVARAAAIVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI00080DC41C +-----ESIEQIESRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE +NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP +NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE +TEFTIQERDKVINEIGQLIFDAy +>[subseq from] Beta-lactamase n=1 Tax=Promicromonospora sukumoe TaxID=88382 RepID=A0A2U1EKE6_9MICO +----AAEIGRLEKKYDAVVGLYAVDTGTGVEV-AHRADDRFAYASTFKALAAAAVLDRSG +--PEELERVVTYGAGDLQAHSPVAERHLSDGMTMHQIIDAAVQESDNTAGNLLLDALGGP +QGLADALRAIGDETTKPARYEPELNDVTPGDERDTSTARALAHDLRAYGLGDVLDDDARA +TLVEALRGSVTGPETIRAGVPDGWVVGNKTGTSGRGGRNDIGLLWPPDGEPVVLAVLTRT +EDPEAEPDDALLAEVTEVAV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SAB2_KLEPN +---------RLERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYG------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010F87F2D +------------RDRSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAC--------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI000E66E78B +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRGDERFAYASTIKAPLAAALLDRVG +--IAGMERAVPIEAADILSYAPVTETRVGGTMTLRELADAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPADWTVGDKSGSGAYASRGDVAVIWRPDAAPIVIAVHSSK +DQQDATADDALISGAAKAAVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI000F564131 +---AQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTALLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTAFRLDRWEPELNQAAPGDERDTSTPVAMVDMLQRLLLGDTLREPQRA +QLTEWMTGGAT---GIAAGVPPGWRSAGKTGTGGYGTTTDVAVLWPPSRAPIMLAVSFTQ +PRADAAARADVVASAARIAA--- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Pseudomonas salina TaxID=1323744 RepID=UPI0012386724 +-qRVAQDVKAIGTSLSARIGISVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QEKVNPSSTFEIKKTDLVAYSPVVEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP +EGVTDFLRQIGDKETRLDRIEPELNEAKLDDLRDTTTPKAIASTLNKLLFGSVLSETNQK +KLESWMVNNQVTGNLLRSVLPVGWNIADRSGAGGFGARSITAFVWSEHQSPIIVSIYLAQ +TEASMADRNDAIVKIGRSIFDVy +>[subseq from] class A beta-lactamase n=1 Tax=Malikia spinosa TaxID=86180 RepID=UPI001370AA46 +--TLSKAVQAEETRLGARIGMAVFDAKDGTRW-AHRGDERFPLNSTHKSFSCAALLKKID +RRVLALDNQISIERASLVTYSPVMEK-AGSQVSLREACAASVSWSDNTAANIVTDVIGGT +HAFTAFMRDIGDPHTRLDRKEPEMNEATPNDLRDTTTPNAIVESLRRIVLGDVLREDSRA +LLTDWMVNDKVADALLRASLPRAWSIADKSGAGGHGSRSIVAIIWPQNRNPFVVGIYITQ +TAAPMVDSNAAIARLGNVLVD-- +>[subseq from] Beta-lactamase n=1 Tax=Cellulomonas shaoxiangyii TaxID=2566013 RepID=A0A4P7SM64_9CELL +--DLTAALADVEARHGVRLGVHAVDTAQGRTT-GHRADERFAFCSTVKPLAAAAVLAAR- +-GVAGLDEAVPVTADDLVDFSPVTGERIGGTMTWRELGDAAVRYSDNTAGNLLLRDAGGP +TGLTAYVRGIGDDVTRSDRWEPGLNATAPGDERDTSTPRALAATYGTLVVGDALGARERE +VLADWLVRNTTGDALVRAAARPGWTVGDKTGAGAYATRNDVAVVWPPEGAPVVLAILTDR +PSPDAERTDAPLAEAAAVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium simiae TaxID=1784 RepID=UPI0003FF2EB2 +---FYDRLAELERQYNAYIGLFATNVGSGRTL-AHRDDDPFAMCSTFKAYAAARVLQQAQ +RGELDLQQRIFVDPAALLPNSPVTAPQAGNAMPLAQLCAAALQHSDNAAANLLLAQIGGP +PAITDFARSIGDQRTRLDRWEIDLNTAIPGDPRDTSTPRALGTGIQRLLTGTVLGEAQRS +QLERWLRDNVT--SSMRAGLPPGWITADKTGSGNYGSTNDVGMVYGPSGQRVSLSLMTRS +QSVDADGLRPLIAEVTKSVL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Mycolicibacterium duvalii TaxID=39688 RepID=A0A2A7NHL2_9MYCO +---VEQRFEELQRRDNALIGVHAVNLDTGKTL-SFGDDRMLAMCSTFKGYAAAAVLQRAH +RGELALTDAVAVEAADLRPHAPATEPRVGTTMTLTELCVAAVQQSDNTAANLLLRTLGGP +QAITEFARSIGDDRTRLDRWETELNSAIPGDPRDTTTPRAIGTGYRNLLTGDALAPGDRA +LLEEWMRGNWT--SSMRAGLPDGWTTADKTGSGDYGTSNDVGVAYGPAGQRLLLSLMVRS +AGPDAPSLRPLIGELAALAVA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A165PCU7_ECOLX +------------------------------------------MMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMEN---------------- +>[subseq from] carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B3DE277 +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAQLLQQQIGGGVITVLHGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAA------- +>[subseq from] Beta-lactamase Toho-1 n=2 Tax=Legionella donaldsonii TaxID=45060 RepID=A0A378JA20_9GAMM +---IQEKLAKLEASSGGKIGIYAINTANGQQI-HYRANQRFPMGCTSKVMGVAAILKKSM +SDPTLLSQKMTYTKKDLTNWAPIAEKHLNTGMTVAELCAASISYSDNTAMNLLVKKLGGL +EKINDFARSIHNETFRQDNGWPEALSGGPNNVYDSSTPKAMAQSLQQLALTNVLAKPQHE +LLLSWLKSNTTGDKRIRAGVPKGWIVGDKTGTGTYGTTNDLGVIWPPQCAPIVIAVYYTN +NNKEAIQRDDIVSSVTRLVIDGf +>[subseq from] class A beta-lactamase n=1 Tax=Bordetella genomosp. 13 TaxID=463040 RepID=UPI0011A24635 +---IEARLKALETRAGGRLGVAVLDTATGRLA-GSRLDERFALCSTFKALAAACTLARVD +RGQERLERRIFFTEQDLVMPFKATQPHLADGMTIGQLCEAAVTVSDSTAANLLLASLGGP +SAFTAYMRSLGDSVTRLDRMELGLNIVKPGETHDTTSPRAMAGTLREVMLGHALSEPSRK +TLTDWMTESRDAERRLRLGLPKGWRIANKPGTWEGISTNDIGVIFPPGRDPVVVAAFLAE +APGTIEQQEAVLSEVARIVAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. ST5x TaxID=2100817 RepID=A0A2S9Q2Y9_9ACTN +--EVDRKLAALEKKYDAHLGVYAVDTGSGREV-GRHADTRLSYNSTFKALLAGAVLKRNG +--ADGMDRVLRYGKGDLLENSPVSEKHVKDGMSLRALSDAAVRYSDNTAANVLLKDLGGP +KALGALLRETGDRVSHVDRIEPDLSTWTPGEQRDTTTPRQQAANLRAFVLGDVLGAKERT +LLTGWLRANTTGDRTIRAGVPEGWVVGDKTGTGHHGARDDIAVIWPPGRAPLVVAIMSYR +DAKDAEPDDRLIAEAASVVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. WL8 TaxID=2603899 RepID=A0A5C8WT22_9RHIZ +--SAAARIAAVEARLGGRVGVAFRD-APGVFL-GHRAGEAFAMCSTFKVLAAAAILARAA +AGAETLDRRIAYGAADLQSYGPVTRAALANALSVEALCAAAIVWSDNTAANLLLDALGGP +AALTAWLRGQGDAVTRLDRTEPTLNTALPGDPRDTTSPSAITGTLERCLLGDVLTPPHRA +RLEGWMVTCETSRTKLRAGLPLDWTVGDKTGSGDNATSNVVAILHPPGRPPIVAGLFLTG +SEAPPATRDAAHAEIGRILVE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Acidipila sp. EB88 TaxID=2305226 RepID=A0A3P0XCK3_9BACT +-----DPLQAMEHRYGGRLGVFALDLATGRTL-THRADERFLWCSTMKLPLVAAVLARVD +RGEERLDAPVHYMRQDLFPHSPVTEQHVAEGMSVEELCAAAMTVSDNGAANLLLRRIGGP +AALTRFVRSAGDAVSRFDRFELALNR--PSGELDTTTPRAAVMLLKSLVLGTALGAASRR +RLVEWLCATTVGVHRLRAGFPATWMVGDRTGTGDT-ETNDIAVAWPQGRRPILVAALYNQ +GEVSIDTREEAIRNIGSVIA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. BK558 TaxID=2512172 RepID=A0A4Q7Q7W3_9MYCO +---VTDRIDALRRRHNAEIGLYAVDLDSGREI-AVGDGDTYALCSTFKAYASAAILQRAQ +QGRLSLTDAVPVERTDIQPHSPVTEPRVGTTMTLAELCQAALQQSDNAAGNLLLRTLGGP +AAITDFARSVGDDRSRLDRWETALNSAVPGDPRDTSTPRALGAGFRAVLAGDALDGAHRQ +QLDTWMRANGT--SSMRAGLPAGWSTADKTGSGGYGTTNDVGIAYGPQGQRWLLAIMTRA +VGPEAPNMRELIGEIASVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia rhamnosiphila TaxID=426716 RepID=UPI000B0ADC1F +--DLSNTLMTLQAKYNVLFGIAAVDTRGGRTF-EWNADDRFALCSTFKVYAVAAILRLAE +RKQLDLNDKVPITRQDIVMSSPVVSDHVGELMSYYELSRAALVRSDNTAANLLLRRLGGP +GAVTEFARSINDSQTRLDRWEPELNEARAGDPRDTGTASALAAGYRKLILGDGLSTEYRR +MLTSWMRSSVTSRQRLRAGLPVGWVAADKTGSGAYGTANDAGVVWSPTGSSLVLVVFSRS +TTPMAAGADAAVADATAAVL--- +>[subseq from] Beta-lactamase n=2 Tax=Rhizobacter gummiphilus TaxID=946333 RepID=A0A1W6L9N3_9BURK +--DLSTAMTSLQARAGGKLGVFVQDTGSGDFI-SFNAESRFAMASTFKVLLAATVLQRVD +TGTVSLDQTVAFGRRDLLSYAPVTSRRVADGMSVRDLLAASLELSDSTAANLLLGLVGGP +SAVTDFVRGTGDVTTRLDRIEPDLNSNLAGDLRDTTTPIAMARTLQAVLLGRHLTIASRA +HLQAWMVAATTGKRRLRAGMPELWRVGDKTGSGDNGAFNDVAMAWPPAGAPLVFSVFMTG +ATAPPETLDAIHVVVARLAVR-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. 10N.222.47.A9 TaxID=1903178 RepID=A0A1R3ETV0_9VIBR +-----ESIEQIESRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE +NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP +NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TELTIQERDTVINEIGQLIFDAy +>[subseq from] Beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=A0A2N7KUN2_VIBSP +-----ESIEQIESRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE +NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP +NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TELTIQERDTVINEIGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium phlei TaxID=1771 RepID=UPI00025AEDEC +-----TAIRALEQRHNARIGVYAVNLATGRTV-THRAQEPFAMCSTFKTYAAARVLQMAE +RGELSLTDPVFVDPAAIVRHSPRTEPRAGGDMTLDELCQAALQISDNTAGNLLLQTIGGP +QAITAFARSIGDERTRLDRWEIALNSAEPGDPRDTSTPEAIGGGYRALLTGDAKGAPQRE +LLVRWMRANET--SSMREGLPAGWTTADKTGSGDYASSNDVGVAYGPRGERLLLALMART +AGPDAPTLRPVIGELAG------ +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonadales bacterium TaxID=1978525 RepID=A0A4Q3CG54_9SPHN +--KASARIAAIEARLGGRIGVSAIDTGSDAEI-NHRAQERFAMASTFKWLLAAGVLKRCE +-EGLNLDAVMYFTPSDMLPTSPVTSAEISATLSVEQLCEAIVTVSDNAAANLLLVPMFGP +EGLTRFLRESGDPHTRLDRVEPELNENRPNDPRDTTVPHAMARTLRRLLTDEVLNANSRA +RLTGWMEKASTGLDRLRAGFPDGWRAGDKTGTGGNGSHNDCCIVWPPGRSPIVIASYLSE +SAAPNIEKAAAHAEIARIIVEDf +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium marinum TaxID=1781 RepID=UPI000E3BE563 +--DLESRFAELEQKYEARLGVYVPGTDATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP +--IAHLGTVITYNSADIRSTSPITEQHLATGMSIGGLCDATIRYSDGTAANLLLQDIGGI +AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALLPEKRD +KLIDWLGRSTTGAKRIRAGFPADWRXIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR +VGPEAPWCDPLVADAAKCVAD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Vibrio antiquarius (strain Ex25) TaxID=150340 RepID=A0A657NBG4_VIBAE +---LEQRVQYF-EDKGWSIGVTVLDTESGNIN-SVNGDKRFHFNSTIKALACANILSKVD +KNKISLDDSIYLKKSDIVTYSPVTEDYVGKKLTLRKACKASLTYSDNTAANYTISAGGGP +EGLTKFMRSIGDDVLRSDRYEPELTKNIEYDIRDTTTTNAMASSLNKLLLENVLSEESKL +QLKQWMKGNKVANDLLRASLPQGWAIADRSGASDYGVRGIISMAWSKDHEPLIITMYVRK +SNTTMKERDQVIAEIGKVIFEQy +>[subseq from] class A beta-lactamase n=2 Tax=Saccharomonospora piscinae TaxID=687388 RepID=UPI0011067FD9 +--RVDAEFAKLERTYERRIGVLATNMRTGQSL-EHRPDERFPICSVFKVLLAAQVLRDLP +--VSVMDRRLTWSTDELVINSPVTEQTVRNGLTVAQLAEATVTVSDNTAANVLMREFGGP +AAVTGFARSLGDRVTRVDRWEPEMSTGTPGDERDTTSARAIARTYAALVLGRALDESARK +RLRTWMLANRTAGPVFGSGVPANWTLADKTGSGWYGVRNDVGITWTPDGSPLVIAAFTRG +TRYEDETLSEPLAEVAASAC--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI000F4F1E6E +---LEQRVQYF-EDKGWSIGVTVLDTESGNIN-SVNGDKRFHFNSTIKALACANILSKVD +KNKISLDDSIYLKKSDIVTYSPVTEDYVGKKLTLRKACKASLTYSDNTAANYTISAGGGP +EGLTKFMRSIGDDVLRSDRYEPELTKNIEYDIRDTTTTNAMASSLNKLLLENVLSEESKL +QLKQWMKGNKVANDLLRASLPQGWAIADRSGASDYGVRGIISMAWSKDHEPLIITMYVRK +SNTTMKERDQVIAEIGKVIFEQy +>[subseq from] Beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=A0A510UGQ5_ALIFS +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIIPWSPITEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSKTLNALLFGNTLNQQDKQ +TLKSWMMNNKVSDPLLRAILPSDWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio sp. ES.045 TaxID=1528103 RepID=UPI000ADFE0D8 +---LEQRVQYF-EDKGWSIGVTVLDTESGNIN-SVNGDKRFHFNSTIKALACANILSKVD +KNKISLDDSIYLKKSDIVTYSPVTEDYVGKKLTLRKACKASLTYSDNTAANYTISAGGGP +EGLTKFMRSIGDDVLRSDRYEPELTKNIEYDIRDTTTTNAMASSLNKLLLENVLSEESKL +QLKQWMKGNKVANDLLRASLPQGWAIADRSGASDYGVRGIISMAWSKDHEPLIITMYVRK +SNTTMKERDQVIAEIGKVIFEQy +>[subseq from] Beta-lactamase n=1 Tax=Vibrio fortis TaxID=212667 RepID=A0A5N3S4V8_9VIBR +--TLNDSIYSIEQRTLGRIGVSVLD-STDQRW-HYKGNERFPMMSTFKTLACAKMLQDSD +RDILDISTMAPVKSDELIAWSPITKNMVGSLITIENACEATMKTSDNTAANIVLKHIGGP +QGVTAFLRLTGDKVTQLDRFEPELNQAKADDLRDTTTPNAMNKTLHHILFEDVLAQNSKK +QLKEWMQGNTVSDSLLRSVLPQGWSIADRSGAGANGSRGITAAIWTDEREPLIISIYLTQ +TNLSMPERNQVINEIGKAIFEEy +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium marinum TaxID=1781 RepID=UPI000B979EFD +--DLESRFAELEQKYEARLGVYVPGTDATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP +--IAHLGTVITYNSADIRSTSPITEQHLATGMSIGGLCDATIRYSDGTAANLLLQDIGGI +AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDAWLPEKRD +KLIDWLGRSTTGAKRIRAGFPADWRVIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR +VGPEAPWCDPLVADAAKCVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea zeae TaxID=1642303 RepID=A0A5S4GTH0_9ACTN +--RARKDLRKLEVSFKGRIGAYAIDTATGKTV-AYRAGERFPMLSTFKAPLCAAVLQKAR +TAPGLMGRVVKWTAADMKPNSPVTEKHVKDGLTVGRLCAAAVTRSDGTASNLLLKQIGGP +AGLTRYFRTLKDSASRMDRWHPELNDWTPKDVRDTTTPAAISADLRVLTTGQALHDKDRE +QLNAWLLANRTGDERIRAGLPKTWTIGDKTGTNSFGGGNDIAVIWPGKGAPIIMAIYTNR +SA-GLPTDNQAIAKTAAILA--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WXI2_9BACT +---LKSVIESFEKNLGGRVGVALLDVRNASGW-YYRADERFPMASTSKALVCALLLKS-- +-GPAALTKKVKVLESDILEYAPVSKTLTGQYVTASDLCAATMRTSDNTAVNKILDTLGGP +KAVTAFLRQIGNTSTRLDRNEPTLNEGRPGDVRDTTTPRAMAKTLQELIFGDTLNQQARS +TLINWLKGNEVGGPLLRAGLPNDWQIADRTGAGGFGTRGVVAAVWPTERSPVVIVIYLTN +TKASMDQRNAAIARIGREIA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. GA-2829 TaxID=1772283 RepID=A0A117JQ96_9MYCO +----ATELETLERANDVAIGVYAVNLDTGRTV-SHRAQESFAMCSTFKAYLAAHVLALVA +RGERSLDQGLYVAAADILPNSPRTEPRVGTEMTLGELSQAVLQVSDNAAANILLRDVGGP +QAITAFARGIGDPRSRLDRFETELNSAVPGDPRDTTTPEAIGGGVRTLLTGDVLPPEQRG +LLEEWMRANET--SSMRPGLPAGWTTADKTGSGDYGTTNDVGIAYGPQGERLLLSILTRS +ASADAENNRPLIGEVATVVFA-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. AT1 TaxID=1961706 RepID=A0A1V4PQH5_9MYCO +----GDQFAALERRYDAFIGTWAAALDGGRSV-ANRADDTFAMCSTFKAYAAGRVLQKDQ +TGALQLTDAVTIEAGDVVANSPVTEPRVGQNMTIGELCEAALQRSDNTAGNWLLRIIGGP +SAVTASARTLGDDRTRLDRWETDLNSAVPGDPRDTSSPRALGGGYQRLLTGDVLDAPHRA +QLERWMRGNQT--SSLRAGLPAGWTSADKTGGGAYGSTNDVGVVYGPDGRRAVLSIMTRS +RTDDAHDLRSLVAEVTTLVL--- +>[subseq from] Beta-lactamase n=1 Tax=Gammaproteobacteria bacterium RIFCSPHIGHO2_02_FULL_39_13 TaxID=1798270 RepID=A0A1G0G3Y8_9GAMM +-qTVSQKLNQLEIQNHVDIGLSAIETYNNTHI-NFNANKRFPMDSTSKVMTVAAILKKSE +SDPAFLKQRIFFTENDVRKYAPITSKYVKDGMTIFNLCAAALEYSDNAAVNQLMKIVGGP +NQVTQFARSIGDQKYFLVRWEPKLNSAIPNDKRNTTTPEAMADSVQKLVLGHALNNSQRA +LLRSWMKHCKTGDHRIRAGVPNDYLVADKTGTGGYGSIGDIGVIWRAHQSPVVLVVYVRQ +NEKNARTPDKVIAQATKILMN-- +>[subseq from] class A beta-lactamase n=1 Tax=Promicromonospora sp. PT9 TaxID=2219658 RepID=UPI00101B649E +---VGAAVRRLEERYDSVVGLYAVDTGTETEV-THRADRRFGYASTFKALAAGAVLERSG +--PEELARVVNYDADDLQEYSPVAERHVDEGMTMYQIIDAAVQQSDNTAGNLLLDALGGP +AGLQSALRAIGDETTRPARYEPELNDVVAGDVRDTSTPRALAHDLRAYGLGDVLDDEVRA +TFVEALRGSVTGMETIRAGVPEGWVVGDKTGTSGRGGRNDIGIVWPPGREPVVLAVLTQT +KDPEAEPDDALLAEVTAVAVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A2S5VDJ1_9MICO +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRGDERFAYASTIKAPLAAALLDRVG +--IAGMERAVPIEAADILSYAPVTETRVGGTMTLRELADAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRACALGDPLDADERA +LFTGWLKATQTGATLVRAELPTDWTVGDKSGSGAYASRGDVAVIWRPDAAPIVIAVHSSK +DQQDATADDALISGAAKAAVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 02-925g TaxID=2022503 RepID=A0A260PTN8_9NOCA +---AEQNYLDLEARDAARLGVSAVDLATGSTD-SHRGDERFAFCSTFKVYAVGAVLAAAD +AGELQLTDTRTITEKDKVPESAVD-WAPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT +DALTEFARSLGDTEFRLDRTEPDLNTAIPGDPRDTTTPNSMAAGYRTLLHGDVLTPPSRD +QLLAWMADTQTSDARFRAGIPEQWTSADKTGTGSYGVSNDAGLLLGPDGQKILLVVLSTT +ASENSPAMNALVADTTRAVVDE- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Micromonospora arborensis TaxID=2116518 RepID=A0A318NDM6_9ACTN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTAGITVRELCSAAITMSDHTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAG--------------------------- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=A0A1X1VV64_MYCGO +----DTELAALEERYNTSIGLFGLNTASQRAL-AFRADDMFATCSTFKAYVAAQILQQDQ +RGELRLTDTVYIDPAAAVPASPVTEPHIGGRMPLSELCAAAVRHSDNTATNLMLAMLGGP +ASVTAFARSVGDDRTSMVRWETELNTAYPGDPRDTTSPRAMGTGFLNMLTGDVLDAPHRA +QLQEWMRTIVTGDRRIRAGLPPGWSIADKTGSGDYASTNDIGVASRPHGERLLLAVMTRS +RSPNAVASETLIADVTRLAV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL94_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPXSXKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGE-------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=Q7M176_PROMI +-rQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGS +KGVTDFLRQIGDK-TRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNKK +KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ +TQASMAERNDAIVKIGRSIFDVy +>[subseq from] RCP family class A beta-lactamase n=1 Tax=Yangia sp. PrR007 TaxID=2706884 RepID=A0A6B2N8U6_9RHOB +--ALRGTVARIEEQLGARVGLSLLDTGSGRSW-AHREDELFLMNSTVKVPVCGAILARSD +AGTLSLSDSLPVREADLVPYAPVMETRVGGTMTLDELCLAAVDQSDNVAANILIKHLGGP +EAVTQFFRSVGDPTSRLDRREPELNTFAPGDERDTTSPAAMSETLRALLLGDMLSPQARG +QLAEWMRHGGVTGALLRAEAEDDWLILDKSGSGRH-TRNLVAVIQPEGEAPWIATMFVSD +TDAAFEVRNAALKDLGRAVV--- +>[subseq from] Beta-lactamase AST-1 n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A645DSN7_9ZZZZ +--MLQQRLKALEARSGGRLGLSVQLAGGERGF-GYREDEAFPMCSTFKLLLAARILHLSQ +LGEFPLEQALLYEKNELVPYSPVTEKHADAEMTVRALCEAAVVQSDNTAANLLLTLQGGP +AGLTRWLRTAGDMRTRLDRTEPQLNSAVAGDMRDTTTPRAMARTSLALLTDKKLNPASQK +QLRDWLLASRTGDKRLRAGMPGDWIVGGKTGSGENGTANDVCIVWPTKGAPMVVSAYLTG +AKVDADGRNAILADVGHVVGDW- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A481SPE2_KLEPN +-------------------------TCSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRX +QFVDWLKGNTTGNHGIRAXVPADWAVXDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHS--------------- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=A0A1N6KIG2_9BURK +----TNPISNIERRRGGRLGVFAIDTGSGRTL-AYRADERFLMCSTFKGLLAAQVLARVD +AGKENLDRLVHYTEKDLIFTSPVTKANVAQGMSVRAMCQAIVEVSDNTAATLLMRDAGGP +PALTQFVRGLGDTVTRSDRYEPDSNQY--SGARDTTTPKAITKSVGKILLGNVLSAQSRQ +QLESWMIDCEPGLDRIRAALPTDWVAADRPGTSVEEETNDYAIVRPPGRAPLLVAAYYDA +PYVDMDGREAVMREVGAAFVD-- +>[subseq from] Beta-lactamase n=1 Tax=Comamonas sp. JNW TaxID=2170731 RepID=A0A363RMC5_9BURK +--ALHKALTLIEAQSGGRLGVYAFDAETGGEA-GYRSDERFAMCSTFKTLLAAHVLYLGQ +TGALDLGQQVRVTSADMVPYAPVTEKYQDQPISLLELCEAIVVVSDNVAANLLLRASGGP +EALTAWLRTLGDKATRLDRIEPLLNTAAPGDPRDTTTPRAMQATLQALLLGDVLKGYGRA +MLQQWLSDSRTGDQRVRAGLPSEWRVGGKTGAGAHSTANDCLIAWPNAAEGLIITAFLTG +GERTTAQSDAVMAKVGAAIAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus iheyensis TaxID=182710 RepID=A0A2P1WN90_9BACI +---------------------------TGIIF-AYRAEERFAFASTYKALAAAIMLKQNS +--MEELNEVITYTEDELVTYSPVTEKHGDTGMTLLEIGEAAVRKSDNTAGNLLFEALGGP +AEFEEALREIGDDVTQSDRYETELNEFNPEDTRDTSTPKALATNLKKFAVGDLLPDEKRE +LFTDWLQGNATGDTLIRAGAPEGWIVGDKSGAGTYGTRNDIAVVWPPDREPIVIAIMSRH +DTEDADYDDALISEAAKVVFD-- +>[subseq from] carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Aeromonas salmonicida TaxID=645 RepID=UPI001024A3DA +--AFESQIRTLETEFDGYVGVHAVNTGTGKIL-QYRSDERFPLCSSFKGFLAAAILKKSQ +QEEGLLAENVRYIGREMEHHSPITKQYQSTGLSVSAMSAATVQYSDNGAANMLMERIEGP +KGLTTFMRGIGDNEFRLDRWELELNSAIPGDERDTSTPKAVAESLQKIALGSVLQQPQKK +IFQQWLIGNTTGDARIRAAVPKEWKVGDKTGTCGYGTANDYAIVWPDKSEPLVIAIYTKS +KEKHKKHSDKLISEVAGIVIK-- +>[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI001158E21C +-qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE +HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACLATMTTSDNTAANIVIYAVGDP +KSITDFLRQLGDTETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK +KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLDQ +TEDTMAERNDEIVKIGR------ +>[subseq from] Beta-lactamase n=2 Tax=Microbispora TaxID=2005 RepID=A0A5D0P9W9_9ACTN +--AVRKALRRLEVSFRGRIGAYAIDMATGITI-GYREGERFPLASTFKAFAAGAVLAGTT +-EAELTRQVVRWTAGEVKPHSPQTGRHVADGMTLAALCRAAIVHSDNTAGDLLLKRIGGP +RGLTRYFRSLGDPVSRLDRWEPELNVWSPRERRDTTTPVSIARDLRALTTGGALDAADRS +RLVGWLRGNTTGDARIRAGLPPKWIVGDKTGTGGYGTANDIAVVWPADAAPIILAIYTNR +LTPGGSADDEVVARTATVLV--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI0009EA103A +-aQARDMLGDITAEIGGRLGVSVFDTGRGWRL-GIDPDTRYPLCSTFKLPLAAAILARAD +MSQLPLNRMIRYSEADLLDYAPAVRANLAAGMSVLELCEAAVVLSDNSAANLLLPQIGGP +AGLTRFFRAHGDRLSRLDRDEPTLNIFRREDPRDTTTPLAMTMLMERLLIGEALQPVSRG +RLIEWMVASQTGAKRLRAGLPKGWRTGDKTGTSGAGQYNDIAITWPPGGKPILIAVYIDA +PGLAAERADAAMARIGGLVGDVf +>[subseq from] Beta-lactamase n=1 Tax=Kibdelosporangium phytohabitans TaxID=860235 RepID=A0A0N7F3P6_9PSEU +-----EHLVALERKYDARLGVFALNTSTGASV-AHRADERFAFCSTFKGLAAAAVLHRNP +--MSHLDTLVRYAEGDLLKSGVVTSQHVATGMTIRQLCDAAIRFSDGTAGNLLLRDLGGP +QQLTDYLRGLGDTVTRMDRTEPAIVEATPGDPRDTATPRSLGTDYQKIVLGDALPEDKRA +LLRDLMERPATGAQRVRAGLPKDWRVADKTGTGDYGTLNDIALVWPPGKPPLLIAIMSSK +AAKDAKYDHQMLAEAASYA---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI14_KLEOX +--AIHQKLTDXEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDY------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0010BDD638 +-qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS +--IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRN +ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWP-------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. SBT000027 TaxID=1803384 RepID=A0A3L7DQ87_9VIBR +-----ESIEQIESRVSARIGVAVYDSTTEQTW-SYKGDERFPMMSTFKTLACANLLYDHE +NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP +NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TELTIQERDTVINEIGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Rhodobacteraceae bacterium Alg231-04 TaxID=1922228 RepID=UPI000D5509A6 +----QKELQMIEARSGGRLGFAALDTQDGRRS-TWNSGDRFALNSTFKFRLAAAILMRVD +DGQETLTRRIPVPAKGLVEWSPLTRANAGHDMTVDQLCAAAVSFSDNTAANLLLDSLGGP +KGLTQLMRAAGDGMTRLDRTEPSLNGATTGDPRDTTTPDAMLAAMGDLLTGDLLQTASRQ +RLAGYLHNSTTGASRLRAGLPGNWTAGDKTGTGNNGAVSNIAILYPPGRAPVLVAAYFQD +SHRPQADLDALHAELGRLVS--- +>[subseq from] class A beta-lactamase n=1 Tax=Aureimonas leprariae TaxID=2615207 RepID=UPI001247820D +--ALAGTVAALEKRTGGRLGVSVVDTASGAAW-SHRGGERFPITSTFKAFACAHLLDLAD +KGEVDAKQRVRFEARDLEEYSPITKTRTGGEMSLLELCDAATATSDNSAGNFILAHTGGP +AALTGFMRRIGDGTTRLDRTEPALNDVGPGEVRDTTSPDAAAASLRKLMLGDALSEPSRR +QLETWLVADKVGGPLLRASLPEGWRIADRTGAGAYGSRSVIAVVWPKTRGPIVAAVYLTD +TTLDLDGRNAVVAEVGAALVK-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. L17-MgMaSL7 TaxID=1938893 RepID=A0A317MF96_9ACTN +--DFEAEFEALEEEFDARLGVYALDTGSGEEV-AFQEGERFAFASTFKALLAGVVLSGNS +--LEEMERVVTFDESVLVPHSPVVEENLESGMSLLELCDATVRFSDNAAANLLLEEIGGP +EGFGSALEETGDDVTNPVRWEPDLNEAVPGDERDTSTPEALAGSLEAFTLGEVLPEDRRE +VLVDLLVRNTTGDDLIRAGVPEGWVVGDKTGGGGHGTRNDIAVLWPEEGDPILLAVLSSR +DVEDAEYDDALVAEATEVVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Serratia liquefaciens TaxID=614 RepID=Q7X5K5_SERLI +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTHYPGQHGRDPAQAADQPASERPFAT +AAAAVDGGRRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium ulcerans str. Harvey TaxID=1299332 RepID=X8FCG8_MYCUL +--DLESRFAELEQKYEARLGVYVPGTDATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYS +--IAHLGTVITYNSADIRSTSPIIEQHLATGMSIGGLCDATIRYSDGTAANLLLQDIGGI +AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALLPEKRD +KLIDWLGRSTTGAKRIRAGFPADWRVIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR +VGPEAPWCDPLVGDAAKCVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. WL18 TaxID=2603897 RepID=UPI0011C7AE39 +-----PALAEIERRLGGRLGVSAG-TQERVLL-SHRADELFPMCSTFKALAVAAILARVD +AGSESLDRAVGFGPGILLSYAPVTRKVVEAGMTISDLCAAAIVWSDNSAANLLLTALGGP +EALTVWLRGTGDTRTRLDRDEPTLNTALPGDPRDTTSPEAMRQTLGRVLLGPVLSAASRG +QLEAWMVGCQTGAKRLRGGLPPDWIVGDKTGSGDNGTFNDVAILRPPGRAPVLACVYVTG +ATAPAAAVEAAYAEIGRLMA--- +>[subseq from] SCO family class A beta-lactamase n=1 Tax=Rhizobium sp. TH135 TaxID=2067451 RepID=A0A2N4Y0R5_9RHIZ +-----AAAQRVETELGMRVGFAVIDTGSGEMR-SYRADERFAMASTFKTLACATALSA-- +-GEAVLAKETKIRKADLRPHSPVTEKRVGTSLSTRSLCEITLRTSDNAAANAILKSIGGP +SELTAFLRRIGDGTTRLDRYEPELNEATPGDPRDTTTPQAMAETLQRLLLDGALEPEARD +QLEAWMAANAVADGLLRAELPVGWKIADRSGAGGHGTRGVVALLQRPVGAPLVVAIYMDG +RKHPLKTRDAAIASIGKAIFAEy +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura kijaniata TaxID=46161 RepID=UPI0009FE1E74 +--DLERTLRELETSYQGRVGAAAIDMSTGKAV-GYRAHESFALNSTFKAYACAAVLRKSD +SDPGLMDRLLHWKTGDLLPNSPETEEYTDTGMTPAQLCRATITKSDNLAGNLLLKQIGGP +AGMTGFFRSIGDPVSRLDRYETELNVWRPGEKRDTTSPAAAAGSLARLTVGDALDPRDRK +RLIGWLRGTVTGDTRIRAGLPKDWTVGDKTGTGGHGTANDVAVAWPPGAAPIVITVYTHR +NTNGVEHDDKVVASTATALAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI00062E6C5F +-------VQY-FEDKGWSIGVTVLDTESGDMN-SVNGDNRFHFNSTIKALACANVLSKVD +ENRISLDDSISLKKSDIVTYSPVTEDYIGKKLTLRKACEAALTYSDNTAANYTISAGGGP +EGLTKFMRSIGDDVLRSDRYEPDLTKNIEYDIRDTTTTNAMASSLNKLLLENVLSEESKL +QLKKWMKDNKVANDLLRASLPQGWSIADRSGASDYGVRGIISMAWSKDHEPVIITMYVRK +SNTTMKERDQVIADLGKVIFEQy +>[subseq from] Beta-lactamase n=2 Tax=unclassified Mycobacterium TaxID=2642494 RepID=A0A5Q5BIW5_MYCSS +-------LDALERANTAVVGVFAVNLDTGRTV-AHRAQESFAMCSTFKAYLAAHVLQLVG +RGERSLEQGLYVDAADILPNSPRTEPRVGGEMTLAELCQAILQVSDNAAANILLRDVGGP +PAVTAFARWIGDPRSRLDRYEIELNSAVPGDPRDTSTPEALGGGFRTLLTGDVLAPPQRR +LLEDWMRANET--SSMRAGLPPGWTTADKTGSGDYGTTNDVGIAYGPQGQRLLLAVMTRS +ATPDAENMRPLIGEVTAAVL--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=A0A2S7UL81_VIBSP +-----ESIEQIESRVSVRIGVAVYDSATKKAW-SYKGDERFPMMSTFKTLACANLLYDAE +NKGLDLDSKVNIKSEDLIVWSPVTKELVGKGISLRDACSATMTMSDNTAANIVLGGIDGP +NGLTQFLRSIRDSNTRLDHLEPELNHARPGDARDTTTPNSIVMTLNELMYGDTLSQASKA +TLKGWMMDNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWSEHRAPLIISVSLTE +TEFTLQQRDKVINEVGQLIFDTy +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhizobium TaxID=2613769 RepID=UPI0012604FD0 +--SIEEDIRLIETKSGGELGVAVLDTGTNQVV-GHRLDERFALCSTFKVLAIAFVLARVD +QGKEQLDRRVDFSEQDLVLPYKATKPHVGAEMTIDELCKAAAIYSDSTAANLLLASFGGP +AELTDYLRSIGDNVTRVDNVEPKLNIVKPGELHDTTSPRAMAETMKRIILGDMLSPRSRG +LLTDWLVNGQDATQRLRKGVPAGWRIANKPGTWKGISTNDVGVIWPPHRPPVVVAAYLSH +APGSIESQEAVLADVARRVCD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Bp8990 TaxID=2184552 RepID=UPI000F5ADBF1 +---AQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTALLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTAFRLDRWEPELNQAAPGDERDTSTPVAMVDMLQRLLLGDTLREPPRA +QLTEWMTGGAT---GIAAGVPPGWRSAGKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ +PRADAAARADVVASAARIAA--- +>[subseq from] Beta-lactamase n=2 Tax=Ralstonia insidiosa TaxID=190721 RepID=A0A191ZU84_9RALS +---LQQATQREEEALNARIGVAVIDKESGMTW-SYRGDEAFPINSTHKAYLCAALLEKVD +QKQLALSDRTTLSKRDLVAYSPITETLLPPQASNAQLCEAAVSHSDNTAANKVLEKIGGV +DGFNGFMRSIGDQKTRLDRKEPELNEGTPGDPRDTTTPVAAVRSLDQIFFSDHLSRSSKS +ELKTWMVNDKVAADLLRKSLPAGWDIADKTGAGGYGSRSIVAVVYPRGKKPLLVSIYITQ +TKATLGESNAAIARMGAILFK-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. ITM-2016-00316 TaxID=2099695 RepID=A0A2S8LK54_9MYCO +--TLEEQIRELEARDNAFIGLYAVNLESGLSL-ENRADEAFALCSTFKTYAAARVLRGVA +DGEFTLEQPVFVKPEGILPNSPVTGERLGQEMTLAELSQAALQRSDNLAANLLLETIGGP +QAITAFARSIGDDRTRLDRWEIELNSAIPGDPRDTTTPRALAAGYRNLLAGDALPPAQRE +LLDGWMRANQT--SSMRAGLPPGWTTADKTGSGDYATTNDSGVAYGPDGARVLLTIMTRT +QSADAEGLRPLIGEVAALVL--- +>[subseq from] Beta-lactamase 1 n=1 Tax=Streptomyces cacaoi TaxID=1898 RepID=BLA1_STRCI +--AHEKEFRALEKKFDAHPGVYAIDTRDGQEI-THRADERFAYGSTFKALQAGAILAQVL +AEADGMDKVVHYGQDAILPNSPVTEKHVADGMSLRELCDAVVAYSDNTAANLLFDQLGGR +RGSTRVLKQLGDHTTSMDRYEQELGSAVPGDPRDTSTPRAFAEDLRAFAVEDALAPNDRE +QLNDWMSGSRTGDALIRAGVPKDWKVEDKSGQVKYGTRNDIAVVRPPGRAPIVVSVMSHG +DTQDAEPHDELVAEAGLVVAD-- +>[subseq from] Beta-lactamase n=2 Tax=Listeria rocourtiae TaxID=647910 RepID=A0A4R6ZDZ9_9LIST +--DTTTQLKNLEKKYQATLGVYAIDSGSGETF-AHNGNQRFAFASTVKALLGGVLLKNLS +--WDELNQIIKYTKDDLVSYSPITEKHVDTGMSLKDIIAAAIQYSDNTAANLMFKQFGGP +KGFESQLRELGDKVTDSSRLEPDLTTAIPGDIRDTSTPKAIAETFKKLLLDRKIAPDKLK +FYNEILTGNATGEELIRAGVPSNVKVGDKSGAASFGTRNDIAVLYPPHRAPIILVVFSNK +TNEDDEYDNALIADAARVMSN-- +>[subseq from] class A beta-lactamase n=1 Tax=Acaricomes phytoseiuli TaxID=291968 RepID=UPI00036070E3 +-qELTSLLNRYESDSDLRIGLCAI-VNGEARL-SHRAEEVFPMCSTFKPIAVGAMLAQHA +EDTDYLRQAIRIAQNAVVDYSPITEKHAGATMTLAEICEAALRYSDNTAGNLILEQIGGP +AGVTAFANSLGYRNTRLDRWETELNEALPGDPRDTSTPADLCGIFDALLVGDGLAPAARD +VLRTWMRGNTTSAKRFGAALPAGARLADKTGSGSYGTAHDVGAVFRADAPPVILAVLTRT +QRQDAQSNDAAIAQTARVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora sp. E2A TaxID=2665642 RepID=A0A5Q3QHN1_9PSEU +-------FPELEQRYGARLGVWARNAVTGRTV-HHRPHERFAMTSTFKPYAAAALLREHG +LAGDYFRHRVFFRREDLVVHSPICEQAVDTGMTVLELCDAAITYSDNTAGNLLLTELGGP +AAIAPFARTLGDPATRLDRWEPELNEAERGDPRDTTTPAAIGTGYGRLVLADGLPRPERD +RLTAWLLANTTGDTSIRAGVPPTWVTGDKTGGGSYATNNDVAVTWTDLDQPIIIAVLSDK +PIRDAEPDDALIADAAKRVAE-- +>[subseq from] Beta-lactamase n=2 Tax=Mycolicibacterium thermoresistibile TaxID=1797 RepID=G7CD35_MYCT3 +--AIHQRLTGLENDHDQLIGLYAVDLGSGRTI-AHREHESFAMCSTFKTYLAAATLQRVQ +QGELQLDQRIFVPPAAIVTHSPRSEAAAGGHLTVAELCAAILQVSDNGAANTLLQTLGGP +PAVTEFARSIGDERSRLDRWEVALNSAVPGDPRDTSTPRALGEGYRTLLEGDVLAPPYRE +QLVEWMRTNET--SAMRPGLPPGWVSADKTGSGDYGTTNDVGLLYGPQGQRVVLAILTRS +ASPDAQNPRPLIGEITAAVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium psychrotolerans TaxID=216929 RepID=UPI00138D19EE +-----DRIDALRRRHNAEIGLYATDLESGREI-AVRDGDSYALCSTFKAYASAAILQRAQ +QGRLGLTGTVRVDRADIQPHSPVTELRVGTTMTLAELCQAALQQSDNAAGNLLLRTLGGP +PAITEFARGAGDDRSRLDRWETALNSAVPGDPRDTGTPRALGTGFRAVLTGDVLDPAHRQ +QLEDWMRANET--SSMRAGLPAGWSTADKTGSGGYGTTNDVGIAYGPQGQRWLLSIMTRA +AGADAPNLRPLIGEIASVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. GA-1999 TaxID=1772275 RepID=A0A117JCY0_9MYCO +----DARIGEFERQHNALIGVFAVNLDTGRAI-AHRAQEPFAMCSTFKGYAAARILQKAE +RGELALSDRVAVEQSDIVPNSPVTQTRVGQTMTLAELCEAALQRSDNAAGNLLLRAIGGP +PAITDFARSIGDQRSRLDRWEVELNAAVPGDPRDTTTPEAIGGGYRSMLTGAVLAEPQRR +LLEDWMRANQT--SSVRPALAPGWTTADKTGSGDYGSTNDVGVAFGPDGRRLLLAVMTRS +AGPNAPNMRPLIGELAALLV--- +>[subseq from] class A beta-lactamase n=1 Tax=Comamonas sp. B-9 TaxID=1055192 RepID=UPI0003959AE6 +--ALHKALTLIEAQSGGRLGVYAFDAETGGEA-GYRSDERFAMCSTFKTLLAAHVLYLGQ +TGALDLGQQVRVTSADMVPYAPVTEKYQDQPISLLELCEAIVVVSDNVAANLLLRASGGP +EALTAWLRTLGDKATRLDRPEPLLNTAEPGDPRDTTTPRAMQATLQALLLGDVLKGYGRA +MLQQWLTDSRTGDQRVRAGLPSEWRVGGKTGAGAHSTANDCLIAWPNAAEGLIITAFLTG +GERTTAQSDAVMAKVGAAIAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium chlorophenolicum TaxID=37916 RepID=A0A0J6Z151_9MYCO +---VTDRIDALRRRHNAEIGLYAVDLDSGREI-AVGDGDTYALCSTFKAYASAAILQRAQ +QGRLSLTDAVPVERADIQPHSPVTEPRVGTTMTLAELCQAALQQSDNAAGNLLLRTLGGP +PAITEFARSVGDDRSRLDRWETALNSAVPGDPRDTSTPRALGTGFRTVLAGDALDGAHRQ +QLDTWMRANAT--SSMRAGLPAGWSTADKTGSGGYGTTNDVGIAYGPQGQRWLLSIMTRA +VGPEAPNMRELIGEIASVVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI000A3B38F6 +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADILSYAPVAETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDAAPIVIAVHSSK +DQQDAKADDALISGTAKAAAQ-- +>[subseq from] Beta-lactamase n=2 Tax=Clavibacter TaxID=1573 RepID=A0A067LZ21_9MICO +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAATLLDRVG +--IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDAAPIVIAVHSSK +DQQDAKADDALISGAAKAAAQ-- +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudomonas putida TaxID=303 RepID=A0A2S3XAD2_PSEPU +------TALRLENALDARIGYAIHDTGTGLGW-EHRADERFPMASTVKLLVCSALLRQGQ +---VRMKKAWQIQQESILPHSPVTQNLVGKQVAASDLCAFTLKTSDNAAANGVLEVLGGP +AAVNAFLQEIGDQTTRSDRNEPSLNEGQPGDLRDTTTPKAMAGTMKSLVLGSALKDEPRR +QLTEWLMSNQVGGPLLRAGIPGDWRIADKTGSGGFGTRGVVAVMWPPQRAPIVAAIYLTE +TTASMDERNAAIAEIGRAMVK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillaceae TaxID=186817 RepID=W7ZR08_9BACI +-eTMEQGFSQLEDRYHAILGVYALHTETGETI-ASNEEDRFAYASTHKALSVGVLLQQHS +--LEELDKRVHYNEKDLVTYSPITEQHVETGMTLKELSDASIRFSDNPAANFIFNEIGGP +EGFKHALQDMGDQVTEPKRWETELNHWAPGEVSDTSTAKALVETLHGVALGDELDEEKQD +LFTDWLVHNTTGDTLIRAGVPKGWQAGDKTGSAVYGTRNDIGIIWPPDHAPVVLAVLSHT +DEEDGEVDDHLIADATKEV---- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio kanaloae TaxID=170673 RepID=UPI001244BF78 +------SIAKIESRISARIGVAVYDSATEQIW-NYKGDERFPMMSTFKTLTCANLLYDHE +SEGLDLESKVGIEPDELIAWSPITKSFVGKEISLRSACAATMEMSDNTAANIVLRSTGGP +NGLTEFLRFMGDRKTRLDHIEPYLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWRIADRSGAGAYGSRAITAIVWSETHAPLIISISLTE +TELTIPERDTVINEIGELVFDEy +>[subseq from] Beta-lactamase n=1 Tax=Leisingera sp. ANG-M1 TaxID=1577895 RepID=A0A0C1GM57_9RHOB +-eALAETVSQVEQRLGGRVGLSIKEVDGPTSW-SHREDERFLMNSTVKTPVCGAVLAQRD +AGALTLSDALPVREADLQSYAPVTKSRVGEEMTIGALCLAALDMSDNTATNILIDHLGGP +QAVTQFFLSIGDPISRLDRPEPDLNTFAPGDPRDTTTPAAMAATLEKLLLGHALTAASRD +LLTDWMSHGGVTGNLLRADAPAGWQVFDKSGSGSH-TRNIIAMVTTDKGAPWITTIFLSD +VDADFDTRNAALQELGSAVM--- +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI000CE92C40 +--AADAAFTALEERFDARLGVHLVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADVLSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEAFGGP +AELDAALTALGDETTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLQATRTGDTLVRAELPTEWTVGDKSGSGAYASRGDVAVVWRPDAAPLVIAIHSSR +DAQDAEPDDALISGAARAAVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Leisingera sp. NJS204 TaxID=2508307 RepID=A0A481PGG3_9RHOB +-eALAETVSQVEQRLGGRVGLSLEEVGGQTSW-SHREDERFLMNSTVKAPICGAVLAQRD +AGALALSDALPVRAADLQSYAPVTKTRVGKDMTIEALCFAAIDMSDNTATNILIDRLGGP +QAVTRFFRGIGDPISRLDRREPGLNTFVPGDPRDTTTPAAMAVTLEKLLLGSALSPVSRD +QLADWMSHGGVTGNLLRADASADWQVLDKSGSGSH-TRNIIAMVTPGKGAPWIITIFLSD +ADADFDTRNAALQKLGSAVM--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. UNC267MFSha1.1M11 TaxID=1502745 RepID=A0A1G4W306_9MYCO +---LDQRIGALERRHNAVVGLSAVNLNSPGAV-AHRADQMFAMCSTFKAYAAGRVLEQVG +RGELALEATEFVDPSAVVANSPVTGPRAGSQMTLAELCQAALQRSDNTAANLLLRRLGGP +PAITAFARSIGDDRTRLDRWETELNSAIPGDPRDTSTPAALAGGYRALLTGDVLAPPQRL +LLEQWMRANQT--SSMRAGLPAGWSTADKTGSGDYGSTNDVGVAFGPEGQRVLLAIMTRS +AVDDADALRPLIGELTTL----- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012D90E6A +--SLTQNIEAIELSSGGYIGVSVLNTETNKMW-EYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSVLPNDWSIADRSGAGGFGSRGITAAIWNDNHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea sp. WAC 01424 TaxID=2203200 RepID=A0A429AZP1_9ACTN +--DVKKRLRALENSYQGRIGAYAIDTGTGKTI-SYRGGELFPSASTFKAVLCGAILAKAR +TDPGLLNRTLRWTAKELVTNSPITEENLKNGMTVDRLCHAAVTASDNTAANLLLKQIGGP +AGLTRYYRSLGDPIGRLDRWEPELNDWKPDEKRDTIKPAFMARNLQKLTLGSTLVPEDRQ +RLNDWLRASVTGTERIRAGLPKNWTVGDKTGGGSYAPGNDIAVAWPPSGAPLIIAVYTNR +NDPTATMDNSVIAKAATLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=Q6T3Q5_ALIFS +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIIPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSILPNNWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFNEf +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium moriokaense TaxID=39691 RepID=A0A318HLU4_9MYCO +---IDERIAAIERRRNAYVGLFAADLEAGRSI-SHRGQQAFAMCSTFKGYASARVLQMVE +QGELTLDHEVFVDPAEIVANSPRTQPRAGGGMTLDELCQAALQVSDNTAGNLLLKTIGGP +PAITAFARSIGDPSSRLDRWETALNSAVPGDPRDTSTPEALGGGYRHLLTGDALAPPQRQ +QLEDWMRANET--SSMRAGLPPGWTTADKTGSGDYGSTNDVGVAFDPAGRRILLAMMTRS +QVNDAPNLRLLIAELTSLVV--- +>[subseq from] Beta-lactamase n=1 Tax=Angustibacter sp. Root456 TaxID=1736539 RepID=A0A0Q7JIM7_9ACTN +--QLEAQFTALERRRGGRLGVYALDTGSDRSL-SHRGDERFAMASTVKVLAVAALLDRLS +--AADLGRRLRWTSGDLVAHSPVTERFVDRGMTIRQLIDASLTRSDNTAANLLFEQVGGP +TTVGDFVAAAGDDITSVDRREPALNDWAPGETRDTSTPRALGGTLATLVRGDVLEPADRL +VLERAMRDSVTGAGLVRAGVPDGFVVEDKSGTARYGVRNDVAIVRPPGGAPWILAVMTSH +ETADAEPDDELVAAATRIVVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050C3448 +---AEQSYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTLADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRQ +QLLDWMAGNQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. L17-MgMaSL7 TaxID=1938893 RepID=UPI000D71123C +--DFEAEFEALEEEFDARLGVYALDTGSGEEV-AFQEGERFAFASTFKALLAGVVLSGNS +--LEEMERVVTFDESVLVPHSPVVEENLESGMSLLELCDATVRFSDNAAANLLLEEIGGP +EGFGSALEETGDDVTNPVRWEPDLNEAVPGDERDTSTPEALAGSLEAFTLGEVLPEDRRE +VLVDLLVRNTTGDDLIRAGVPEGWVVGDKTGGGGHGTRNDIAVLWPEEGDPILLAVLSSR +DVEDAEYDDALVAEATEVVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI000CE93D5A +---LEQRVQYF-EDKGWSIGVTVLDTESGNIN-SVNGDKRFHFNSTIKALACANILSKVD +KNKISLDNSIYLKKSDIVTYSPVTEDYVGKKLTLRKACKASLTYSDNTAANYTISAGGGP +EGLTKFMRSIGDDVLRSDRYEPELTKNIEYDIRDTTTTNAMASSLNKLLLENVLSEESKL +QLKQWMKGNKVANDLLRASLPQGWAIADRSGASDYGVRGIISMAWSKDHEPLIITMYVRK +SNTTMKERDQVIAEIGKVIFEQy +>[subseq from] Uncharacterized protein n=1 Tax=Luteipulveratus mongoliensis TaxID=571913 RepID=A0A0K1JPL3_9MICO +----AASLQPLESRHGVRLGVYAIDTGTKREV-AYRADERFAYASTFKALAAAMVVRKVG +--LPGLGRRVPIAQSDIVDNSPVTGKHVGGDMALREIIDAALRFSDNTAGNKLLAELGGP +TGFGRTLQTLGDQVTRPTRWETDLNSGAPGDLRDTSTPRQLAVDLRAVLLDSALPRPEQA +LLRDVMWRNTTGDKTIRAGVPHGWPVADKTGSASYGRRNDIAVIWPPNRSPVVLSVLTAR +DKADAPTVDAAVADATKAVLR-- +>[subseq from] class A beta-lactamase n=1 Tax=Desulfovibrio desulfuricans TaxID=876 RepID=UPI0003B781BD +--DLPKMLAELEASSGGRLGVAASVSNGGNVL-SYRGDERFPMCSTFKVLAAAAVLRDKP +---DILEQRIHFAKNDIQPWSPVSEKHLEDGMTVSELCAAMLQHSDNTAANLVLAQLGGP +AGLTTIARSFGDTTFRLDRWEVELNTAIPGDARDTTTPIAMCRTLNGLLCGNQLKAPAQK +QLTDWMLGCATGAGRIPAGAPQGWRPAHKSGSGENGTANDVGVLLPPKNKPRTVALYLTG +SRLTGSGNDKILAQATRLVC--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Mycobacterium TaxID=2642494 RepID=UPI0004292E84 +---LDQRIAALERRHGARIGLSAVDLDGPGAV-SHRADESFAMCSTFKAYAAGRILQGVE +RGEFPLDATEYVDPAAVVANSPRTGPRAGTELTLADLCQAALQVSDNTAANLLLKRLGGP +PAITAFARSIGDERSRLDRWETELNSAVPGDPRDTSTPAALAGGYRALLTGDALAPPQRS +LLEQWMRANET--SSMRAGLPQGWTTADKTGSGDYGSTNDVGVAYGPDGRRVLLAIMTRS +AADDAAGLRPLIGELA------- +>[subseq from] Beta-lactamase n=2 Tax=Mycobacterium sp. Root265 TaxID=1736504 RepID=A0A0Q8ZV29_9MYCO +--TLEEQIRELEARYNAFVGLYAVNLQSGFAV-ENRADEAFALCSTFKTYAAARVLRGVA +DGELTLEQQVFVKPEGLLPNSPVTGERLGQEMTLAELSQAALQRSDNLAANLLLETIGGP +QEITAFARSVGDDRTRLDRWEIELNSAIPGDPRDTTTPRALAAGFRNLLAGDALPPAQRE +ILDGWMRANQT--SSMRAGLPPGWTTADKTGSGDYATTNDSGVAYGPDGARVLLTIMTRT +QSADAEGLRPLVGEVTALV---- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012DA2124 +--SLTQNIEAIELSSGGYIGVSVLNTETNKMW-EYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTTITKEQIMPWSPITEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSKTLNVLLFGNTLNPQDKQ +TLKSWMMNNKVSDPLLRSTLPSNWSIADRSGAGGFGSRGITAAIWNDNHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] class A beta-lactamase n=1 Tax=Carnobacterium maltaromaticum TaxID=2751 RepID=UPI0010721843 +-kTIDSDLKKLEKEYEATLGVYAIDTETNKTI-NYNGEQRFAFASTYKALAGGLVLDKFN +--WDELNQTIMINQEDLVDYSPITEKYVGVGMPLKDIIGAAMEYSDNTAGNILFDQLGGP +AGFQKELEKLGDHTTESVRYEPELNEAIPGDRRDTSTPKAIALDLKKLTAEKTLAPDKLT +FYKKQLVENKTGGNLIRAGIPTEVLVGDKSGAASYGTRNDIAVLYPPNRKPIVLVIFSNK +TNKDDAYQDELIAKSAKLVGDYf +>[subseq from] Beta-lactamase n=1 Tax=Halomonas halophila TaxID=29573 RepID=A0A510ZAL5_9GAMM +------------------MGVALMNVATGAVA-SHRGDERFLFNSTGKFFIAAAVLARVD +EGSETLDRRVVIEEGDLGGWTPITEKRLGEPLTLAELCQAAVAWSDNAAANALIESVGGP +EAVTAFLREIGDDTTRLDRLEPELNTDHAGDERDTTTPLAMMTTLRTLLLGDVLSPSLRH +QLASWMIEGKTGDARLRAGMPSSWLVGEKTGTNGVGNANDIGIAWPGDRGAVIAVAYTRM +PSATAEQRDETIAAVGRLAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudooceanicola sp. CAU 1508 TaxID=2599291 RepID=UPI00131C2815 +-eALSDTVEQVEQTLGARVGLALVDTGSGRSW-FHRGDERFLMNSTVKVPVCGAVLALDD +AGVLDLSESLPVVQEEILSYAPVTKTRVGQQMTLAELCLAAIDISDNTAANMLIDRVGGP +QAVTAFFRAAGDQASRLDRREPELNSFRAGNPQDTTTPAAMSGTLRALLFGEVLSPAARE +QLAEWMSQGGVTRNLLRADAPASWQILDKSGAGSH-TRNIIAAITPDGGDPWIVTIFVSD +VDADFETRNAALRRIGSAAM--- +>[subseq from] class A beta-lactamase n=1 Tax=Microbacterium sp. SA39 TaxID=1263625 RepID=UPI0005F9E411 +-----ARFTALEERFDVVVGVYAIDTGSGRTV-EYRPDDRFGFASTIKAIAAGLVFSTTT +--DEQLDAPIAVTSDDLVPYSPVIEQRVGGTVSLLEAADAAVRFSDNAAANLLFRHLGGP +EAMETMLRDVGDTTTNADRIEPELNDVSPGDDRDTSTPRAMATTLADLALGDALDVDDEA +RLIDLLQRNTTGDALIRAAAPEGWTIGDKTGSAAFGTRNDIAIAWPPDREPIVIAILTRG +HDVDAEPIDEVLAEAAALVFD-- +>[subseq from] Beta-lactamase n=1 Tax=Gluconacetobacter liquefaciens TaxID=89584 RepID=A0A370G4W1_GLULI +----EGAIAAYERATGGRVGVFARNIASGKSF-AWRQDERFVMCSTFKASLAACVLARVD +RGDADLDEVIAFTAADIGEYAPVAKENLGRGMSVREMCAGAVEFSDNVCANKLLIRIGGP +AALTRFWRAMGDDVTRLDDIEPFLNRTPMGGVRNTTTPMAMAGVVRRLVLGDVLSEGSRA +TLKTWMVNCQTGKNRLRAGLPGQWVVGDKTGNNGKDAAGDIAIAWPGVGGPIVMAVYTRG +GTPNDAQFAALFAGIGRHVA--- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella sp. RIT-PI-d TaxID=1681196 RepID=A0A0L0AXC7_9ENTR +--ALTGYLQQQESQLNARIGMAVVDAQGTPGF-GWRENERFPLTSTFKVLTCAALLDQLH +KKHGSLEERVSLQPTELLDYSPIAKNYLPPEISLRKLCSAAVSYSDNTAANRLLTWLGGP +AAVTQFMRSLDDNVTRLDRTEPTLNMATPGDVRDTTTPHHIVRSLRLLLASDVLTQTDRA +TLDNWMREDNVADALLRSTLPEGWAIADKTGAGGYGSRAIIAAVYPPQKPPFYVAIYITQ +TTASMKTADAVIAEIGRRLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium lusitanum TaxID=293958 RepID=UPI00119AE6BF +--SIEEDIRLIETKSGGELGVAVLDTGTNQVV-GHRLDERFALCSTFKVLAIAFVLARVD +QGKEQLDRRVDFSEQDLVLPYKATKPHVGAEMTIDELCKAAAIYSDSTAANLLLASFGGP +AELTDYLRSIGDNVTRVDNVEPKLNIVKPGELHDTTSPRAMAETMKRIILGDTLSPRSRG +LLTDWLVNGQDATQRLRKGVPAGWRIANKPGTWKGISTNDVGVIWPPHRPPVVVAAYLSH +APGSIESQEAVLADVARRVCD-- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012DA796F +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITQEQIIPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSILPNNWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFNEf +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium cosmeticum TaxID=258533 RepID=W9AY91_9MYCO +---LDQRIAALERRHGAKIGLSAVDLDGPGAV-SHRADESFAMCSTFKAYAAGRILRGVE +RGEFPLDATEYVDPAAVVANSPRTGPRAGTEMTLADLCQAALQVSDNTAANLLLKRLGGP +PAITAFARSIGDERSRLDRWETELNSAVPGDPRDTSTPAALAGGYRALLTGDALAPPQRS +LLEQWMRANET--SSMRAGLPQGWTTADKTGSGDYGSTNDVGVAYGPDGRRVLLAIMTRS +AADDPKA---------------- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC712 TaxID=1848329 RepID=A0A4R4WLA6_9ACTN +----RKELRKMEVAVKGRIGAYALDTATGKTV-TYRAGERFPMLSTFKAPLCAAVLQKAR +AEPGLMNKLITWTGADMKPNSPVTEKHVKDGLTVSQLCEAVVTRSDGTASNLLLKQIGGP +KGLTKYFRTLKDPTSRMDRWHPELNDWTPKDKRDTTTPAAIGRDLRVLTVGRALHAKDRR +QLLAWLLANKTGGERIRAGLPKTWTVADKTGTNSFGGGNDIAVIWPKKGAPLIMSIYTNR +TK-GLPTDNTTIAKTATVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus dokdonensis TaxID=302167 RepID=UPI000989AD94 +----ESEFRLLEKEYNAKLGIYAVDTSNGKTV-SYQAEDRFAYASTHKALAVGVLLQKLT +--LKQLKETVLIKEGDLVNYNPITENHVNKHMSWKELSDASIRYSDNTAANHILNRIGGP +NGFKKALGDIGDNVTNPERMEPELNLVNPGEIKDTSTPKALATSLKAFTIGNVLPKEKQD +LLVDWLKRNTTGNHLIRAGSPRGWEVGDKSGAAPYGVRNDIAIIWPPNKAPIILAILSSK +EEKNAKADDKLIAEATKKVI--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 1554424.7 TaxID=1834082 RepID=A0A1A0LEX2_9MYCO +----YKRLADLEREFDGKIGVYAVDTNNGELI-AHRADERFPLQSTIKLLGVAALLKRGG +ADSNLLQEQVHYSERDLTTWSPVTRKNIAGGMTLEALAEAAISDSDNTAMNLITKALGGP +AEVERFAHSVGNQKYNVEHYEGQLNSD-PHSEVDTSTPKDMATSVQALTVGDALAPPQRA +QLLGWMRNNTVGYKRIRAGVPLGWLVADKTGSGAYGIANDIGIVSSPYCKPIVLAIYTVQ +NRREANAREDIVASATDAILGRf +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella sp. RIT-PI-d TaxID=1681196 RepID=UPI000675EC46 +--ALTGYLQQQESQLNARIGMAVVDAQGTPGF-GWRENERFPLTSTFKVLTCAALLDQLH +KKHGSLEERVSLQPTELLDYSPIAKNYLPPEISLRKLCSAAVSYSDNTAANRLLTWLGGP +AAVTQFMRSLDDNVTRLDRTEPTLNMATPGDVRDTTTPHHIVRSLRLLLASDVLTQTDRA +TLDNWMREDNVADALLRSTLPEGWAIADKTGAGGYGSRAIIAAVYPPQKPPFYVAIYITQ +TTASMKTADAVIAEIGRRLF--- +>[subseq from] Beta-lactamase n=2 Tax=Agrobacterium sp. RAC06 TaxID=1842536 RepID=A0A1B3P1E8_9RHIZ +-----AAAKRVEQKLGMRVGLSVIDTGSGAVV-AYRDDERFAMASTFKSLACAAALSGGD +---AVLEQTTRITKADLRPHSPVTETRVGTSLSTRELCEITLRTSDNAAANAILKVLGGP +AEVTGFLRGIGDATTRLDRYEPEVNKAKPGDPRDTTTPQAMAQTLHRLLLDGALPPPARD +QLEAWMAANAVAGGLLQAKLPKGWTIADRGGAGGHGTRGVVALLRPPQGAPLVIAIYMDG +RKHPLMTRDAAIAEIGEAVFEEf +>[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. 3058 TaxID=2561921 RepID=A0A4Z1BZ91_9RHOB +--DLVETIDSLEDRLNARIGVAILDTRTGQFW-SHRADERFLMNSTVKVPLCAAVLSRAD +---IALTEDLPVRMSDILKYAPVTEQHVGGTMTIDDLCEATIDQSDNTAANVLFHRLGGP +KELTAFLRSIGDGTTRSDRIEPELNTFSEGDERDTTTPAAMVRTLEVLLVGNGLSASAKE +QLADWMRPGGVTGALLRPSAPAGWDVADKSGSGSN-TRNLIAMLTPPDEAPIFFSLSISD +TDADFATRNAALTELSAAVMR-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio kanaloae TaxID=170673 RepID=UPI000494E974 +------SIAKIESRISARIGVAVYDSATDQIW-NYKGDERFPMMSTFKTLTCANLLYDHE +SEGLDLDSKVGIEPDELIAWSPITKSFVGKEISLRSACAATMEMSDNTAANIVLRSTGGP +SGLTEFLRFMGDRKTRLDHIEPDLNHARPGDQRDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRLILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TELAIPERDTVINEIGELVFDGy +>[subseq from] class A beta-lactamase n=1 Tax=Luteipulveratus mongoliensis TaxID=571913 RepID=UPI000696059D +----AASLQPLESRHGVRLGVYAIDTGTKREV-AYRADERFAYASTFKALAAAMVVRKVG +--LPGLGRRVPIAQSDIVDNSPVTGKHVGGDMALREIIDAALRFSDNTAGNKLLAELGGP +TGFGRTLQTLGDQVTRPTRWETDLNSGAPGDLRDTSTPRQLAVDLRAVLLDSALPRPEQA +LLRDVMWRNTTGDKTIRAGVPHGWPVADKTGSASYGRRNDIAVIWPPNRSPVVLSVLTAR +DKADAPTVDAAVADATKAVLR-- +>[subseq from] Beta-lactamase n=2 Tax=Gluconobacter frateurii TaxID=38308 RepID=A0A0K8N3A8_9PROT +---------SYEEATGGHIGVFARNLATGQRL-TWRENERFVMCSTFKASLAALTLLRVD +QGKESLETVVPYTASDLRDYAPVAKANVAAGLSVRAMCQAAVEWSDNACANLLLARVGGP +ATLTQFWRSLGDHETRLDDWEPVLNRTPPGGLRNTTTPAAMAGILQQLVFGHALSGASCS +LLTGWMKNCQTGKGRLRAGFPPTWDVGDKTGNNGKDAAGDIAVAWPTREAPLIVCAYTRG +GHPDEKQFFEVFSEIGRIAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter halimionae TaxID=1926630 RepID=UPI00135E70E1 +---ALEQIEAIEERLGGRLGVSLVD-GSGQALlTHRGDERFAMCSTFKAPLAAAIMLEVE +QGRLSLEQQIEFTQADVVPHAPMIERALEGQRPVDWLVLAAMRASDNSAANILLDRIGGP +EGMTQFYRNHGDGVTRLDRREPELNENSPGDPRDTTSPLAMAQLIRHVMLGDAVHPGLRA +ILVRHMIRTDTGMSRIRAGLPEGWVVGDKTGTCGS-AYNDVAVFWAERDRPYVLSIYYDR +PEAESEEAQAAMAQVGALAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium sediminis TaxID=1286180 RepID=UPI00138B9813 +---VEDRIGALERTYGAYVGVYAENLDTQTSV-AHRADDPFAMCSTFKAYAAGRVLQKAA +AGELNLTDAVTIEQSDILPNSPITETRVGRNMTIEELCVAAVERSDNAAANWLLRIIGGP +SRITDFARTLGDDRTRLDRWEPELNAAVPGDPRDTSTPRAIGSGFRSMLTGEALAEPERR +TLDRWMRGNQT--SSMRPGLGPGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLSFMTRT +RSPDAEAMRPLIGELATLIV--- +>[subseq from] class A beta-lactamase n=1 Tax=Reyranella soli TaxID=1230389 RepID=UPI0011BF9B23 +--DATSRLAELERRNGGRLGVAAIDTASGRRV-GHRAEELFPLCSTFKFLAAAFVLARVD +RGEEKLDRRVFFTDRDLVTYSPVTKQHVGLGMTMAEICEAAVTLSDNTAGNLMLASFGGP +AGLTTYARSLGDRTTRLDRIETELNEAKPGDPRDTTTPVAMLDTMQRLLIGDALSASSRD +QLIGWLLASKTGARRLRAGIPADWKVGDKTG----------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium frederiksbergense TaxID=117567 RepID=UPI001436FBDA +--TLEEQIRELEARDNAFIGLYAVNLQSGFSL-ENRADEAFALCSTFKTYAAARVLRGVA +DGEFTLEQPVFVNPDGILPNSPVTGERLGQEMTLAELSQAALQRSDNLAANLLLETIGGP +QAITAFARSIGDDRTRLDRWEIELNSAIPGDPRDTTTPRALAAGYRNLLAGDALPPAQRE +LLDGWMRANQT--SSMRAGLPPGWTTADKTGSGDYATTNDSGVAYGPDGARVLLTIMTRT +QSADAEGLRPLIGEVAALVL--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 05-340-1 TaxID=2022505 RepID=A0A260H341_9NOCA +--SAEQNYVDLEARDTARLGVSAVDLGSGSTE-SHRGDERFAFCSTFKVYAVGAVLAAVD +AGALQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT +AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTPASRD +RLLAWMTDTQTSDGRFRAGIPEQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT +TSEDSPAMNSLVADATRAAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. ERR1071 TaxID=2572677 RepID=UPI00119D4EAB +--AIEENIRAIETKSGGKLGVAVLDTATDRVV-GHRLDERFALCSTFKALAVAFVLARVD +QGKEHLDRKVVFSKQDLVLPYKATKPHLGPEMTIGELCKAAAIYSDSTAANLLLASFGGP +AALTAYLRSIGDSVTRVDNVEPKLNIVKPGELHDTTSPRAMAGTMKRLILGDVLSPRSRG +LLTDWLVGGQDATQRLRKGVPTDWRIANKPGTWEGISTNDVGVIWPPHRPPVIVAAYLGH +APGSIKSQEAVLADVARCVCD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces katrae TaxID=68223 RepID=A0A0F4JH29_9ACTN +----VRRLREMEREHGARIGVYARNLVTGRTV-ANRAEETFPVCSVFKPLAAAAVLRDLD +RDGEFLARRVHYTAAEVEAWAPVTKDHVADGMTIEALCAAAVSQSDNLAGNLLLRELGGP +TGITRFARSLGDRVTRLDRWEPTLNSAEPWRVEDTTSPRAIGETYVRLLLGNALARKDRD +RITGWLLANTTNTQRFKAGLP-GWTLADKTGGGNYGVANDVGVVWSPAGVPVVMAVLTTR +PEAPGPNDSKLVADTARLL---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia fusca TaxID=941183 RepID=UPI000A06E554 +--DLSNTLMTLQAKYNVLFGIAAVDTRGGRTF-EWNADDRFALCSTFKVYAVAAILRLAE +RKELDLNDKVPITRQDIVMSSPVVSDHVGELMSYYELSRAALVRSDNTAANLLLRRLGGP +GAVTRFARSVDDSQTRLDRWEPELNEARAGDPRDTGTASALAAGYRKLILGDGLSTEYRR +MLTSWMRSSVTSRQRLRAGLPVGWVAADKTGSGAYGTANDAGVVWSPTGSSLVLVVFSRS +TTPMAAGADAAVADATAAVL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Mycobacterium grossiae TaxID=1552759 RepID=A0A1E8Q4S2_9MYCO +---IEERIAELERRYGAFAGVFAQNLVTGATV-AHRADDPSAMCSTFKAYAAARVLQKSA +ARELNLTDAVTIEASDIVPNSPVTETRVGANMTIAELCAAALQRSDNAAGNWLLRIIGGP +SRITDFARSIGDDRTRLDRWEIELNAAVPGDPRDTSTPRALGSGFRDLLTGTVLGASERG +RLEEWMRANQT--SSMRAGLPPGWASADKTGSGDYGVTNDVGVVYGPDGQRLLLAFLTRA +QAPDAESVRPMIGDLAALLVR-- +>[subseq from] Class A beta-lactamase n=2 Tax=Microbacterium TaxID=33882 RepID=A0A6D1IHK9_9MICO +---LTLELAALEAAHGGRLGVFAVDVASGGFV-AYREDERFAYASAIKALLVAAVLRKIP +----DLERVVVFSEEELVFQSPVTQQHAGTGLTIRRLCEAALRDSDNTAANLLLEELGGP +AGFEIALREMGDHTTMPARFETDLNSATPGDDRDTSTPRALARSLRSVIAEDLLPDGRAT +LLIEWMSGNATGDTLIRSGAPPDWLVADKSGTGGYGTRNDLAVVWPPGAGPIFIAVMTTS +ESKEAAPADSLVARAAALAL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. 7209-2 TaxID=1850373 RepID=A0A4S8NDI8_9RHIZ +----TAAAQAVETRLGMRVGFAVIDTGGGKTL-TYRADERFAMASTFKALACASALSGG- +--QAVLDKETRITTADLRPHSPVTEKRVGTRLPTRELCEITLRTSDNAAANAVLAAIGGP +PALTTFLKGIGDGTTRLDRYEPELNQATPGDPRDTTTPKAMAETLRHLLLDGALEPGARE +QLEAWMAANAVAGGLLRAELPAGWTIADRSGAGGHGTRGVIALLRPPEGPPLVVAIYMDG +RKHPLKVRDAAIAEIGKAIFAEy +>[subseq from] Beta-lactamase n=1 Tax=Segniliparus rugosus ATCC BAA-974 TaxID=679197 RepID=E5XRK8_9ACTN +---FADAVTALERGHEAEVGVFVLDTGSGKTL-EHRADQRFMMCSTFKALLAGAVLRKAQ +DEPGLLDRSIPVPAEAAAGYAPFGNSRLGKSATLAELCEASIQISDNIAANLLIDFLGGP +PAVTSFFRSLDDTVTRLDRHEEAMSDGEAKDLLDTTTPRAIAKTLHKLALGEALAKPQRQ +QLVDWMLGSVTGTECIRAGLPSEWKVADKTGTGARGERHDIAIVWPTGGAPLAVAILTRV +QN-KAERNDQLLADVASAA---- +>[subseq from] Serine hydrolase n=1 Tax=Kribbella sp. YM53 TaxID=1572659 RepID=A0A4R0JNJ3_9ACTN +----KEQLEQVLGPVHAQAWVHAVDLATGKET-GYGEDTPVVLASVFKIPVLVELFRRFG +DSRLDPATRMDVPVDGRSAGPTGLSVMADPILSLCDLAYWMMSVSDNAATDILVNLL-GT +ESINATVRELGLTATRVDGTCDDIYQIDPDRTLQASTPRDITRLLAAIWNDEAAPPEQCA +EMRRILAGQAW-PHRLRSAFTTGTIVSAKTGTLRF-WRNEAGVVRTPDGRQYAVASFVRT +DDPDLPAVDAAVGSVARILVD-- +>[subseq from] Serine hydrolase n=1 Tax=Kribbella sp. YM53 TaxID=1572659 RepID=A0A4R0JNJ3_9ACTN +----PDEIRAYAGELGAEIWLHARDLATGRTV-GVDAETPVVTASVLKVPVALELARQSV +AGEVDLTERITVPTEGLVASPYGLAMHRDPTISYNDLALLMMVISDNVATDLVIDRV-GK +DRVAALLAELGLPGTAVPQNCAEILAALDPAGTCRTTPDEITSLLAGIWRDEAADPEACA +LVRGWMGNQVW-PHRLSSGFPDDITVSGKTGTLPL-VRNEVGVVEFPDGGRYAVGVFTRA +ADPNAPQFDGLIGWAAA------ +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI00080D949D +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIIPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLSEIGGP +SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSILPNNWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFNEf +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=UPI000940D7BA +---AESPLADIERRHGGRLGVFAVDTGSGRTL-SHRADERFLMCSTFKGLLAAQVLARVD +SGKDSLERFVRYTEKDLIFTSPVTKANVAQGMSVGALCQAIVEVSDNTAAILLMRSVGGP +AALTQFVRSLGDTVTRSDRYEPESNQY--SGVLDTTSPRAITQAVSRILLGDVLSPPSRA +QLESWMVACKPGLNRLRASLPADWRAADRPGTSVEEETNDYAVVRPPGRAPLLVAAYYDA +PGVSMDAREAVLREAGAVFV--- +>[subseq from] Beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=A0A1B9PCI2_ALIFS +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTTITKEQIMPWSPVTEPLVDHIITTKKACEATMLMSDNTAANIVLNEIGGP +RSLTQFLRAIGDDKTRLDRIEPKLNEAKNGDKRDTTTPVAMSETLNTLLFGNTLNPQDKQ +TLKSWMMNNKVSDPLLRSILPSDWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFNEf +>[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas sp. CPCC 204705 TaxID=2306636 RepID=UPI0010A8EFBD +--DLTAALADVEARHGVRLGLHAVDTAQGRTT-SHRADERFAFCSTFKPLAAAAVLASRT +--VAGIDQPVPVAADDLVDFSPVTADRVGGTMTWRELGDAAMRFSDNTAGNLLLRGAGGP +EGLTAWLRTVGDDVTRSDRWEPELNAFVPGDDRDTSTPRALAGTYRTLVVGDVLGAPERD +VLTDWLVRNTTGDALVRAAARPRWTVGDKTGAGAYATRNDVAVVWPGEGAPVVLAVCTDR +PSPDAERTDAPVAEAARVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardioides sp. Soil805 TaxID=1736416 RepID=A0A0Q9SY04_9ACTN +--AFAGRLRHLEREKDAVVGVYAFATGTGEDL-AYRADERFAFASTGKALAAAVVLDQLS +--SRDLSRRLYWTEADLVPYSPVTELHVEDGLTVRAVLEAAVTVSDNTAANLMFDLIGGP +RGLDEALEDVGDDTTEAVRREPDLNDYTPGDVRDTTTPRAIASSLAAFAVGGELKPSDER +LFNNMLLRNTTGDALIRAAVPASWRVGDKTGSASYGTRNDIAVVTSPGRTPVVVAVLTRH +STADAATDDGLVAEAARAVVGSw +>[subseq from] Beta-lactamase Toho-1 n=1 Tax=Legionella feeleii TaxID=453 RepID=A0A378IV15_9GAMM +---IQEKLAKLEASSGGKIGIYAINTANGQKI-HYRANQRFPMGCTSKVMGVAAILKKSM +SDPTLLSQRISYTKKDLTNWAPIAEKHLYTGMTVAELCAASISYSDNTAMNLLVKKLGGL +EKINDFARSIHNDTFRQDNGWPEAMSGGPNNVYDSSTPKAMAQSLQQLALNNVLAKPQHE +LLLSWLKSNTTGDKRIRAGVPKGWIVGDKTGTGMYGTTNDIGVIWPPQCSPVVIAVYYTN +NNKEAIQRNDIVSSATRLVIDGf +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI001428302F +--AADAAFTALEERFGARLGVHAVDTGTGTEV-SWRADERFAYASTIKAPLAAALLDRVG +--VAGMDRAVPIEAVDILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAAYLRAYALGDPLDSDERA +LFTGWLTATQTGGTLVRAELPADWTVGDKSGSGAYASRGDIAVIWRPDAAPLVIAVHSSK +DQQDADADDALISGAAKAAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. 1554424.7 TaxID=1834082 RepID=UPI0009ED5140 +----YKRLADLEREFDGKIGVYAVDTNNGELI-AHRADERFPLQSTIKLLGVAALLKRGG +ADSNLLQEQVHYSERDLTTWSPVTRKNIAGGMTLEALAEAAISDSDNTAMNLITKALGGP +AEVERFAHSVGNQKYNVEHYEGQLNSD-PHSEVDTSTPKDMATSVQALTVGDALAPPQRA +QLLGWMRNNTVGYKRIRAGVPLGWLVADKTGSGAYGIANDIGIVSSPYCKPIVLAIYTVQ +NRREANAREDIVASATDAILGRf +>[subseq from] class A beta-lactamase n=1 Tax=Endozoicomonas ascidiicola TaxID=1698521 RepID=UPI000BA45C8C +-qAVEKQVKKSENALSAQISVAMMNSATDEVW-SYNGNKRVPITSTFKTLLCAKLLQDVD +QERRALSDKVKLEKTMLVDYSPVIEGFLGEYVTLGQACSATMQTSDNTAANIVLENVGGP +NALTKFIRSYGDQVTRIDRFETELNEGTPGDPRDTTSAEAMLHSIDTLLFGDALSVSSKK +QLTQWMIQNTVTGNLLRSVLPEGWVIADRSGAGGYGTRSINAVVWPEDGNPWVITIYVSN +TKAAFEERNKAIVEIGKTMFR-- +>[subseq from] Beta-lactamase n=1 Tax=Sandaracinobacter sp. PAMC 28131 TaxID=1715348 RepID=A0A501XUI2_9SPHN +-----ANLQALEAQAGGRLGFALLDTGTGKII-GHRMDERFGMCSTFKLPLAGLVLQAAE +RGELKLDTLLPITQADLVPHAPETGPNVGKAMRIRDLARVAQMTSDNVAANLLIKQLGGP +AGVTKRLRALGDKATRLDRMEPEMNRVIGNDPRDTTTPRAMAETVARLLTNDALTPASRK +LLGQWMADTQTGMRRLRAATPPGWTAGDKTGTGMTKRVNDVAIFWPPKGAPLVAAAFYEA +PGNSRPQDEAVLVQAMQIA---- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 05-2256-B3 TaxID=2022490 RepID=A0A260IH38_9NOCA +----EQPYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREVGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLTQASRQ +QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQRILLVVLSAT +TSEDSPAMNALVADTTRMVVEQ- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0007C578FB +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDKKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] Beta-lactamase n=1 Tax=Ascidiaceihabitans donghaensis TaxID=1510460 RepID=A0A2R8BBR6_9RHOB +----ARTVATLEKTLDARVGVYLFDSGTGWQW-GHRETERFLMASTFKPLLCGAILAQAD +AGALNLEDRIDVRKQDVVPYAPVTETHVGHSMSIHDLCFATLDLSDNTAANLLTNRLGGP +QNVTAFLQAIGDDVTRLDRLEPDVNTFVPNDPRDTTSPIAMTHSWATLLLGDALQPKSAT +QLAEWLSHGGVTGQFIRAHAPQGWQVLDKSGGGRHHTRNLMAMVTPPGEPPVFVAIFVSD +TPADWDTRNAAVSTLGAAVIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012DA4DB7 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPIAMSQTLNALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSILPSDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEIGNAIFKEf +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium sp. CR10 TaxID=2562314 RepID=UPI0010BFF504 +----DERLKALERKHNVLIGFSAVEVPSGRWL-AHRAKDRFSMCSTFKAYAAADVLRRSE +RGELMLTDTVPVEPTDIIAHSPVAETRVGMTMTLAEMCQAVLQQSDNGAANLLLRVLGGP +PAITAFARSIGDEESRLDRWETELNSAVPGDPRDTTTPLAIGIGFRNLLTGDVLSPAGRR +QLDDWMRANQT--SSMRAGLPKGWTSADKTGSGDYGSTNDVGIAYGPSGQQLLLSIMVRS +AVPDAQNQRPLIGEVAAFAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Aliivibrio fischeri (strain MJ11) TaxID=388396 RepID=B5FDI3_ALIFM +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] Class A beta-lactamase n=1 Tax=Dermacoccaceae bacterium C5-26 TaxID=1660198 RepID=A0A563DVB1_9MICO +------DLDALESTFGGKVGLYALDTGTGAAV-RHRADERFLMCSTYKVLVVSATLSQAQ +ARPRLMDQVVHFRAAEVLPYSPVTSTHTAESMTVSALCDAALTRSDNTAANLLVDLVGGP +TSVTKYVRTLDDPETRVDRDEPALNIA--DGSLDTTTADAIGADLLKLVLGDALTAQNRK +LLTAWLKANTTGDRSIRAGLPRGWAVGDKTGSGVHGEVNDVAVIWPPRRAPLIMAIYTRP +TDPGSTEGYHAVARATRIALK-- +>[subseq from] Beta-lactamase n=1 Tax=Virgibacillus dokdonensis TaxID=302167 RepID=A0A2K9J262_9BACI +----ESEFRLLEKEYNAKLGIYAVDTSNGKTV-SYQAEDRFAYASTHKALAVGVLLQKLT +--LKQLKETVLIKEGDLVNYNPITENHVNKHMSWKELSDASIRYSDNTAANHILNRIGGP +NGFKKALGGIGDNVTNPERMEPELNLVNPGEIKDTSTPKALATSLKAFTIGNVLPKEKQD +LLVDWLKRNTTGNHLIRAGSPRGWEVGDKSGAAPYGVRNDIAIIWPPNKAPIILAILSSK +EEKNAKADDKLIAEATKKVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Thiomicrorhabdus sp. Kp2 TaxID=1123518 RepID=UPI0004282684 +--SLKNTIISIEKQSHGKIGVAVLSTQTQQYW-SYRGNERFALMSTFKTLACAKMLADSD +HNILNKQQTALVDKTKMIPWSPITEQYIGKQMTLEKLCEAAMLNSDNTAINLVLSHIGGP +AAVTKYLQQNGDSVTRIDRIEPELNTAFLNDPRDTSTPLSMVNTLHKLLYGSLLSNASKE +QLKNWMMNNQVSDALLRSILPSNLFIADRTGAGNNGSRGITAVIWGKEKQPLIISIYLTQ +TTLSIQERDKVIVKIGERILQKy +>[subseq from] Class A beta-lactamase n=1 Tax=Carnobacterium maltaromaticum TaxID=2751 RepID=A0A659GSJ3_CARML +-kTIDSDLKKLEKEYEATLGVYAIDTETNKTI-NYNGEQRFAFASTYKALAGGLVLDKFN +--WDELNQKIMINQEDLVDYSPITEKYVGVGMPLKDIIGAAMEYSDNTAGNILFDQLGGP +AGFQKELEKLGDHTTESVRYEPELNEAIPGDCRDTSTPKAIALDLKKLTADKTLAPDKLT +FYKKQLVENKTGGNLIRAGIPTDILVGDKSGAASYGTRNDIAVLYPPNRKPIVLVIFSNK +TNKDDAYQDELIAKFAKLVGDYf +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 1081908.1 TaxID=1834066 RepID=A0A1A3QNA6_9MYCO +-----KRLADLERQFDGKIGVYAVDTNNGELI-AHRADERFPLQSTIKLLGVAALLKRGG +ADSNLLQQQVHYSERDLITWSPVTRKNIAGGMTFAALAEAAISDSDNTAMNLITKALGGP +AEVERFAHSVGNQKYNVEHYEGQLNSD-PHSDLDTSTPKDMATSVQILTVGDALAPPQRA +QLLGWMRNNTVGYKRIRAGVPLGWLVADKTGSGAYGIANDIGIVSSPYCKPIVLAIYTVQ +NRREANAREDIVASATDAILDQf +>[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. NEAU-G17 TaxID=2293572 RepID=A0A372JKN7_9ACTN +--DVHKELRKLEASYQGRIGAFAIDTGTGRTV-GYRTHERVPSNSTFKAILCGAILHKAR +TDPGLLNRTLHWTKEEVVDGSGITGKNIKNGMTVARLCEATITTSDNTAANVLLEQVGGP +RGMTRYYRSLGDPVGRLDGYEPELNHWNPGEKHDTVAPAFMARDLQKLTVGKALVPQDRQ +QLATWMKATTTGDERIRAGVPKGWTVGDKTGTADYAAANDIAIAWPPSGAPVIIVVFTHR +AAKDAKFDNKVIAQTTTVLM--- +>[subseq from] class A beta-lactamase n=1 Tax=Kocuria sp. 36 TaxID=1415402 RepID=UPI00101D43A7 +---VVSRIRELERGLDGEIGVHAFDTSTGACF-GYRDRQPFLLCSVSKVLVAATVLDLAA +DDPQLLGKRLTITQDDLLPYAPVTSQHLEGGMTVEELCAAALTVSDNTASNLLLEQCGGP +ETVTAFVRSTGDVTTRLDRIEPDLNDA--SGTLDTTTPAAFSETLNRLTLGDALAASGRD +KLVGWMKESTTGAEQIRAGLPEGTLTGDKTGSGTHGESNDVAVIWPKQGAPVIMSVFTKS +QRDDTTGQKAAIAGTARAVF--- +>[subseq from] Beta-lactamase n=2 Tax=Acetobacter malorum TaxID=178901 RepID=A0A149ULY8_9PROT +---VASVLSEYEDATGGRIGVYARNLVTGQAL-TWRENERFAVCSTFKASLVALVLLRVD +QGKERLEDVAPYTQADVEKYAPVAQAHVEAGLTVRTLCQAALEQSDNACANLLLARVGGP +AMLTRFWRSLGDTKTRLDDWEPVLNRTPPGGLRNTTTPRAMAGTLEHVLFGDTLSVSSCM +LMTDWLKGCRTGTHRLRAGLPEGWGVGDKTGNNGRDAVSDIAVAWPAPQRPIILSVYTRG +GHPVEEQFRTAFAGIGRMV---- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=A0A1N6JKE4_9BURK +---AESPLADIERRHGGRLGVFAVDTGSGRTL-SHRADERFLMCSTFKGLLAAQVLARVD +SGKDSLERFVRYTEKDLIFTSPVTKANVAQGMSVGALCQAIVEVSDNTAAILLMRSVGGP +AALTQFVRSLGDTVTRSDRYEPESNQY--SGVLDTTSPRAITQAVSRILLGDVLSPPSRA +QLESWMVACKPGLNRLRASLPADWRAADRPGTSVEEETNDYAVVRPPGRAPLLVAAYYDA +PGVSMDAREAVLREAGAVFV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Syntrophobacteraceae bacterium TaxID=2052185 RepID=A0A3B8HNC1_9DELT +-----------------------FDASTGTTW-NYRGDERFPLNSTHKTFSCAALLAKVD +GKSLSLGQSVSISKEMLVTYSPITEKSLSPEVTLGKICQAAVSYSDNTAANVIFDAIGGA +TGFNAYMRSIGDEQTRLDRKEPELNEGTPGDVRDTTTPNAIVNSLRKILLGDGLSVSSRS +ELTQWMLDDQVAGALLRASLPSDWKIADKTGAGGYGSRSIVAVIWPPSKQPLVVGIYITQ +TKASMQASNQAIARIGVV----- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012DAC4B1 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIIPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] class A beta-lactamase n=1 Tax=Citrobacter freundii TaxID=546 RepID=UPI0013EF6548 +------FLKQQEQQLNARIGMAVVNAQGEMMF-GYRQDERFPLTSTFKVLACAALLDKLQ +QTGGSLDEHVTIKPSELLDYAPITKHYLAPALSLRMLCAAAVSYSDNTAGNRILAYLGGP +EAITHYMRRMGDEVTRLDRVEPTLNEATPGDARDTSSPAKMAAGLQKILTSSSLSPAYRE +TLTTWMREDKVGDALLRAALPTDWAIADKTGAGGHGSRAIIAAVYPPKQPPFYVAMYITQ +TIAPMKTADATIAATGKRLF--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. Leaf233 TaxID=1736302 RepID=UPI00070A4EAA +----EQPYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRQ +QLLDWMAGNQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. FUKUSWIS1 TaxID=1379701 RepID=UPI000A68A52C +-------VAAYEAASGGHVGIYARNLTTGRAI-AWRADERFVMCSTFKASLAACVLNRVD +RGRARLADRIALVPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLRQVGGP +AALTAYWRRLGDDVSRLDDIEPFLNRAPPGGLRNTTTPRAMAATIGRLTRGPVLSPSSRA +LLMLWLRQCRTGAARLRAGLPQGWVIGNKTGNNGRDAAGDVGVLWRDPDTPIIISVYTRG +GTPTEAQFKTLFSKVARGVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus sp. C1-24 TaxID=2495913 RepID=A0A5A7S5U3_9NOCA +-qKLDSRLAALEQQYNARVGVAVDRPSDGAEY-RHRGDETFAHCSTFKVYAASALLRLVA +AGSASLDTTVVIDAAAVVANSPVTAKAAGSPMSMGDLCLAALTQSDNTAGNYLLHAIGGP +PAITAFARSVGDTTTRGDRFETDLNTAIPGDLRDTSTPAGLAAGFGATILGDGLQPDGRA +QLQDWMRRSLTSAARIRAGLPQGWTSADKTGSGDYATVNDAGVVWDPAGKPVVVAILTTT +RSQDAPADGKLVVDITAAIIETf +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0004BD7D39 +--QTAERFAKIEQKFDARIGVQAVDTGTGRQV-AYHADERFAYASTHKAFTVAAVLDKYS +VDGLD-KKKIAVKASDPVGHAPVTEANVGKKLTLRELCEAAVRQSDNGADNLLVRDLGGP +KKLEAFLEGLGDHVTEVSRYEPDLTEATPGDTRDTTTPRAFTKDLRAVVLEKGLGKQERK +LLDSWMLNSPTGTKLIRAGVPDDWKVSDKSGAGRYASRSDIAVVRPPGKAPIVVSVMSKR +TEEDASYDDRLVSEAATVVAD-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces albus TaxID=1888 RepID=A0A4Z0VM90_9ACTN +--QTAERFAKIEQKFDARIGVQAVDTGTGRQV-AYHADERFAYASTHKAFTVAAVLDKYS +VDGLD-KKKIAVKASDPVGHAPVTEANVGKKLTLRELCEAAVRQSDNGADNLLVRDLGGP +KKLEAFLEGLGDHVTEVSRYEPDLTEATPGDTRDTTTPRAFTKDLRAVVLEKGLGKQERK +LLDSWMLNSPTGTKLIRAGVPDDWKVSDKSGAGRYASRSDIAVVRPPGKAPIVVSVMSKR +TEEDASYDDRLVSEAATVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI0003736022 +-----ESIEQIESRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE +NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP +NGLTEFLRSIGDSETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSVTRAPLIISISLTE +TELTIQERDTVINEIGQLIFDAy +>[subseq from] Beta-lactamase n=2 Tax=Methylosinus sp. C49 TaxID=2699395 RepID=A0A679F082_9RHIZ +---IEAELEELEARSGGRLGVAVLDSATGRIM-GNRIDERFAMCSTMKALAVAHVLARVD +LGKERLDRRIVFTEHDLVTPYKATQPHVGPEMSIEALCEAAITVSDSTAANLLLTSFGGP +TALTAYLRSLGDHVTRSDLFELKLNVVKPGETHDTTTPRAMVGTLHRLLLGDALSEASRA +RLTSWMVEAKDATRRLRVGLPAGWRIANKPGTWEGISTNDIGVIWPPGREPIVVAAYLGN +APGSTAAQEGVLAGVARIMAE-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium sp. GF69 TaxID=2267251 RepID=A0A329LZ06_9MYCO +-----DRIGAMERSNNALIGVFATNLDTGRTV-AHRAQDPFAMCSTFKGYAAARVLQKAE +RGELALTDRVIIDQGDIVPNSPVTQTRVGQAMTLTELCQAALQQSDNAAGNWLLRVIGGP +SGITDFARSIGDERSRLDRWETELNAAVPGDPRDTTTPEAIGGGYRSILLGGVLAEPQRQ +QLGDWMRANQT--SSVRPALPPGWTTADKTGSGDYASTNDVGIAFGPDGERLLLAIMTRT +AGADAPNNRPMVAELAKQLV--- +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI001269D020 +--AADAAFTALEERFGARLGVHAVDTGSGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMERAVPIEAADILAYAPVTETRVGGTMTLRELADAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVARTEPDLNEATPGDDRDTTTPRAAAAYLRAYALGDPLDADERA +LFTGWLKATQTGGTLVRAELPTEWTVGDKSGSGAYASRGDIAVIWRPDAAPIVIAVHSSK +DQQDADADDALISGAAKAAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptacidiphilus oryzae TaxID=348818 RepID=UPI000A036EAF +hpAAAAAFAALERRYRARLGVYAVDTGSGRAV-AYRADERFGYCSTFKALAAGLILARAT +--DARLGTVLHYRRSDLLAHSPVTSEHLAEGLPLRAVLAAAVQYSDNTAGDLLLKELGGP +SGLAAALRGLGDRVSLPARTEPALNVIAPGDTRDTSSPRAFGTDLRRLALGDLLPAARRA +QFAALLRGNTTGGAYIRAGVPAGWRVGDKTGSSTAGIRNDIAVLWPPRGAPIVLAVMTDR +GAAQPPATDPLIADATRSAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0007C4EAE7 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIIPWSPITEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. OK233 TaxID=1882795 RepID=A0A2C9BWF4_9BURK +-------LADIERRHGGRLGVFAIDTGSGRTL-THRADERFLMCSTFKGLLAAQVLSRVD +AGKEDLGRRVTYTGKDLIFTSPVTKAHVAEGMSVGALCQAIVEVSDNTAAVLLMRSAGGP +AGLTQFVRGLGDTVTRSDRYEPESNKY--SGVLDTTTPRSITNSASKILLGNVLSPQSRA +QLENWMIACKPGLNRLRAALPPDWKAGDRPGTSVEEETNDYAIVRPPGRAPLLIAAYYDA +PALDMPAREAVLREVGAVFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI00117EAD56 +--AADAAFAALEERFGARLGVHAVDTGSGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMERAVPIEAADILSYAPVTETRVGGTMTLRELADAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAAYLRAYALGDPLDADERT +LFTGWLTATQTGGTLVRAELPAHWTVGDKSGSGAYASRGDIAVIWRPDAAPLVIAVHSSK +DQQDADADDALISGAAKAAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudooceanicola marinus TaxID=396013 RepID=A0A1X6YHV4_9RHOB +-eALSNTVARIEEQLDARVGLSLVETGSGWSW-SHREDERFLMNSTVKVPVCGAILARWD +AGTLSLSEALPVRKADLVPYAPVTETRVGGTMTLDQLCLAAIDMSDNVAANLLIGHLGGP +EAVTQFFRSVGDITSRLDRIEPELNDFTPGDERDTTSPAAMSETLRALLLSDALSPQARG +QLAEWMRHGGVTGALLRAEADDDWLILDKSGSGSH-TRNLVAVIQPDGEAPWIATMFVSD +TDAEFEARNEALKDLSRAVV--- +>[subseq from] Beta lactamase protein (Class A), carbenicillinase n=2 Tax=Rhizobium TaxID=379 RepID=N6VAW1_9RHIZ +--------------------------AGGKRI-EHRAGERILMCSTFKALVAALVLARVD +KGEEKLDRRIRYTKSDLLGNSPATEANVGNTMTVAELCAAAVTLSDNAAANLLLASFGGP +KALTAFCRSLGDEITHLDRVEPELNYDTPDDQRDTTTAAAMLENLRRLLFTDVLSLASRS +QLAAWLIMTKTGDARLRAGLPKDWLVGDKTGTSDVGNANDIAVLWPSDRAPIIVTAYCEI +PGISAAERNAVIAEIGRIAA--- +>[subseq from] Beta-lactamase n=2 Tax=Methylosinus TaxID=425 RepID=A0A177PLT1_9RHIZ +---IEAELEELEARSAGRLGVAMLDCATGRII-GNRIDERFAMCSTMKALAVAHVLARVD +LGKERLDRRIVFTERDLVTPYKATHPHVGPEMSIEALCEAAITVSDSTAANLLLNSFGGP +TALTAYLRSLGDHVTRSDLFELALNVVKPGETHDTTTPRAMVGTLRRLLLGDALSQASRA +RLTSWMVEAKDATRRLRVGLPAGWRIANKPGTWEGISTNDIGVIWPPGREPIVVAAYLGN +APGSTAAQEGVLASVARIMAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Parvularcula sp. CL28 TaxID=2580516 RepID=UPI0012BC8967 +--------------ASARIGVLAQDLSRSRRI-AWRADERFAMCSTFKWLLAAQILAEAD +AGTLLLSDMVTFQEHDLVPYSPVTGPLAVEGASVATLCAAAVSKSDNTAANLLLRLVGGP +HGFTRKLRSWRDGVSRLDRWEPDLNENRSGDARDTTSPAAMADLLRRVLFGDTLTGDSRK +LLMAWMEAADTGLTRLRAAIPEGWAAGDKTGTSNNGANNDVAYFRRPDGAPIVIASYINA +PNSDRSTINAIHAEIGMLIIDIf +>[subseq from] Beta-lactamase n=1 Tax=Myceligenerans xiligouense TaxID=253184 RepID=A0A3N4YMR1_9MICO +------AFTGLEEAYQARLGVYARDTGTGRHV-AYRADERFPFLSTIKTIAAAEVLEDST +--RADLGTTILYGPGDLVEWSPETEEHAGEGMPLGDVLRAAITASDNTAANLVLDRLGGP +HALEARLRGDGDDVTSVDRPEPELNEWSPGETRDTTTPRAIAAQFQEDVLGDELSEPMRG +FLVRALRDNKTGDDLIRAGVPEGWDVGDKTGSAG-GMRNDLAVLVPPGGDPIILAVYTHT +NDPDAESDPALIAEATRVVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI0013658B56 +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADILSYAPVAETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVITVHSAK +DQQDADADDALISGAAKAAAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382) TaxID=443906 RepID=A5CUH3_CLAM3 +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGQ +AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSSK +DQQDADADDALISGAARAAAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Beijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIB 8712) TaxID=395963 RepID=B2IKN6_BEII9 +---IQARLRELESRSGGRFGVAVLDTATGGLV-GNRIDERFAMCSTCKVLAVGCVLARVD +RGEERLDRRITFTERELVSPFKATSPHVGPEMTIAALCEAAITISDSTAVNLLFASFGGP +AALTIYLRSLGDPVTRLDHMEPALNIVKPGEIHDTTSPAAMAGTLRQLLLGDALSDTSRA +LLTGWMIGAKDATHRLRDGLPAGWRIANKPGTWEKIATNDIGVIWPPGRAPIVVTAYLGE +VPGSVESQEAILADVARIVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Methylosinus sp. sav-2 TaxID=2485168 RepID=A0A4R8HRK7_9RHIZ +---IEAELEELEARSGGRLGVAMLDCATGQII-GNRIDERFAMCSTMKALAVAHVLARVD +LGQERLDRRMVFTERDLVIPYKATQPHVGPEMSIEALCEAAITVSDSTAANLLLTSFGGP +TALTAYLRSLGDHVTRSDFFELTLNVVKPGETHDTTTPRAMVGTLRRLLLGDALSEASRA +RLTSWMVEAKDATRRLRVGLPAGWRIANKPGTWEGISTNDIGVIWPPGREPIVVAAYLGN +APGSTAAQESVLASVARIMAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI001365578F +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADILSYAPVAETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDYTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDAAPVVIAVHSSK +DQQDAKADDALISGAAKAAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. 1081908.1 TaxID=1834066 RepID=UPI0012E9C497 +-----KRLADLERQFDGKIGVYAVDTNNGELI-AHRADERFPLQSTIKLLGVAALLKRGG +ADSNLLQQQVHYSERDLITWSPVTRKNIAGGMTFAALAEAAISDSDNTAMNLITKALGGP +AEVERFAHSVGNQKYNVEHYEGQLNSD-PHSDLDTSTPKDMATSVQILTVGDALAPPQRA +QLLGWMRNNTVGYKRIRAGVPLGWLVADKTGSGAYGIANDIGIVSSPYCKPIVLAIYTVQ +NRREANAREDIVASATDAILDQf +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI000CE7B851 +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAMPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDVDERA +LFTGWLKATQTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSAK +DQQDADADDALISGAAKAAAQ-- +>[subseq from] Beta-lactamase class A n=3 Tax=Mycobacterium bohemicum TaxID=56425 RepID=A0A0U0WBS3_9MYCO +-----DRLDELERQYGAYVGVYALNIDTGRSL-AHRDGDPFAMCSAFKAYAAARVLQMAQ +RGELDLQQAVFVDPATLLPNSPVTAPAAGHPLPLAQLCAAALQRSDNAAANLLLRAIGGP +PAITEFARSIGDDRTRLDRWETDLNTAIPGDPRDTSTPRAFGGGIQSLLTGTVLDEPRRR +QLEDWMRANVT--STMRAGLPAGWTTADKTGTGDYGSTNDVGIAYGPDGQRVLLSLMTRS +QAQNADPLRPLIAEVTRTVL--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium rhodesiae (strain NBB3) TaxID=710685 RepID=G8RLV6_MYCRN +---VEALIQGLEQKHNASIGVFATNLASGKTV-AHRAQEPFAMCSTFKAYASGRILQMAQ +HGELSLDDPMFVDPAGILPNSPVTAPRAGGEMTLAELCQAVLQQSDNAGANILLNRIGGP +QAITAFARSIGDHQTRLDRWETELNSAIPGDLRDTSTPEALGAGFRALLDGDVLAPPQRG +LLDDWMRANQT--SSMRPGLPAGWTSADKTGSGDYGSTNDVGIAYGPEGQRVLLAIMTRT +QANDAENLRPLIGEVTTLVM--- +>[subseq from] Class A beta-lactamase n=1 Tax=Parvularcula sp. CL28 TaxID=2580516 RepID=A0A6A8QVL1_9PROT +--------------ASARIGVLAQDLSRSRRI-AWRADERFAMCSTFKWLLAAQILAEAD +AGTLLLSDMVTFQEHDLVPYSPVTGPLAVEGASVATLCAAAVSKSDNTAANLLLRLVGGP +HGFTRKLRSWRDGVSRLDRWEPDLNENRSGDARDTTSPAAMADLLRRVLFGDTLTGDSRK +LLMAWMEAADTGLTRLRAAIPEGWAAGDKTGTSNNGANNDVAYFRRPDGAPIVIASYINA +PNSDRSTINAIHAEIGMLIIDIf +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio kanaloae TaxID=170673 RepID=UPI000C825A04 +------SIAKIESRISARIGVAVYDSATEQIW-NYKGDERFPMMSTFKTLTCANLLYDHE +SEGLDLESKVGIEPDELIAWSPITKSFVGKEISLRSACAATMEMSDNTAANIVLRSTGGP +NGLTEFLRFMGDRKTRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWRIADRSGAGAYGSRAITAIVWSETHAPLIISISLTE +TELTIPERDTVINEIGELLM--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI00099CFF93 +--QTAERFAKIEQKFDARIGVQAVDTGTGRQV-AYHADERFAYASTHKAFTVAAVLDKYS +VDGLD-KKKIAVKASDPVGHAPVTEANVGKKLTLRELCEAAVRQSDNGADNLLVRDLGGP +KKLDAFLEGLGDHVTEVSRYEPDLTEATPGDTRDTTTPRAFTKDLRAVVLEKGLGKQERK +LLDSWMLNSPTGTKLIRAGVPDDWKVSDKSGAGRYASRSDIAVVRPPGKAPIVVSVMSKR +TEEDASYDDRLVSEAATVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00056BFFFF +---LEEQFAALEQRFDARLGVFAVDLDSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD +AGTLSLTETRVVEAEDKVPGSAIDW-EAGQAVTLEQLCAAALTRSDNTAGNLLIDAVGGT +GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTGGPLSNSSRA +TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLAADGRRILAVVLSRT +ASPDAAAMNELVADAVREIV--- +>[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A371YJC9_9GAMM +-----NSIKEVEQNLGAKVGVSIYSVSDGYLW-HYNGDSRFPLMSTFKPLACAKLLHDVE +TAKLSIDRSVKIEEQDLITWSPITEKLVGESFSLKQACTAALVMSDNTAANIVLDGISGP +SELTLFMKELGDEVTRLDRIEPHLNEARSGDERDTTTPNAIVKSLGKLLYGEKLSSGSKE +QLIEWMAGNKVSDSLLRSVLPEGWSIADRSGAGGFGSRGITAAIWSNEQQPLIVAIYLTQ +TEASFDERNKAIAKIGREIFASy +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050C73BA +----EQPYSQLEARDTARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVITIADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRQ +QLLDWMAGNQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. 32-66-10 TaxID=1970437 RepID=A0A258H137_9SPHN +-------FDRIRAETGGRLGVAVYDSGTGRRF-SDGAEARFAMCSTFKMPLVAAVLARVD +RGELNLANEIRFGEADLLDYAPVVKANLAKGMSIDALCEAAVVMSDNSAANLLFGQIAGP +RGLTKFIRDAGDKLTRSDRDEPSLNNVRNGEVRDTTTPDAMLWLMNRLLLGDVLTPASRA +KLIGWMEASPTGKARLRAGLPKDWRVGDKTGTSGEGYFNTIAIATPPGRKPILIACYLDA +PGLESAKANAAHAKVGELVG--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. OK233 TaxID=1882795 RepID=UPI000BE46AFB +-------LADIERRHGGRLGVFAIDTGSGRTL-THRADERFLMCSTFKGLLAAQVLSRVD +AGKEDLGRRVTYTGKDLIFTSPVTKAHVAEGMSVGALCQAIVEVSDNTAAVLLMRSAGGP +AGLTQFVRGLGDTVTRSDRYEPESNKY--SGVLDTTTPRSITNSASKILLGNVLSPQSRA +QLENWMIACKPGLNRLRAALPPDWKAGDRPGTSVEEETNDYAIVRPPGRAPLLIAAYYDA +PALDMPAREAVLREVGAVFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050C4F17 +----EQPYSQLEARDAARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRQ +QLLDWMAGNQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI000808CC66 +-----ESIEQIEFRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE +NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP +NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TELTIQERDTVINEIGQLIFDAy +>[subseq from] Beta-lactamase n=1 Tax=Cryobacterium sp. Sr39 TaxID=1259198 RepID=A0A4V3ISV5_9MICO +--NADAKFTNLEAAHDARLGVYAVDTGTGEEV-VWRSDERFAFASTSKALSAAALLDSVG +--IAGLSADVDVAAEDIVSSSPQTQQHVGASMTLGELAAASVQHSDNTAANLVVEHLGGP +AGFDSALSRIGDDTTEATRTEPSLNEWVPGDRRDTTTPRALTMDLRTYVLGDVLSGEERE +LLTTWLIDHSLGDTLVRAGTPQGWTVGDKSGAAAYGTRNDIAVIWPPSGSPIVIAVMSSR +TEADAEYDDALVAAAASAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012DA9868 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIMPWSPVTEPLIGKMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDKKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNSQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050BEAD0 +----EQPYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLTQASRQ +QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQRILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 14-2686-1-2 TaxID=2023145 RepID=A0A260TYZ9_9NOCA +---LEEQFAALEQRFDARLGVFAVDLGSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD +AGTLSLTETRVVEAEDKVPGSAIDW-EAGQAVTLEQLCAAALTRSDNTAGNLLIDAVGGT +GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTGGPLSNSSRA +TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLAADGRRILAVVLSRT +ASPDAAAMNELVADAVREIV--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. PBTS 2 TaxID=1653479 RepID=A0A143QHA6_9NOCA +----EQPYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVVTLADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLTQASRQ +QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012D8BEE3 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIIPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGCGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012D91D80 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIIPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAIGDDETRLDRIEPELNESKNGDKRDTTTPVAMSTTLNALLFGDTLNQQDKQ +TLKSWMMNNKVSDPLLRSILPSDWSIADRSGAGGFGSRGITAAIWNGKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SDM9_9BACT +--TLSKAVQAEEARLGARIGMALFDAKDRTRW-AHRGDERFPLNSTHKSFSCAALLKQVV +RRVLALENVISIERASLVTYSPVMEKT-GGQVTLREACAASVSWSDNTAANIVTDAIGGP +QAFTVFMRDIGDPHTRLDRKEPEMNEATPNDLRDTTTPNAIVESLRRIILGDVLREDSRA +LLTDWMINDKVADALLRATLPRTWSIADKSGAGGHGSRSIVAVIWPKDRDPVVVGIYITQ +TSAPMADSNAAIARLGSVLAD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces turgidiscabies Car8 TaxID=698760 RepID=L7F7J9_9ACTN +---------------------FAHNLGTRQTI-RHRADERFPVCSLFKTLAAAAVLRDLD +RSGEVLSKRVHYTADDLVDGSAETEKHLTEGMTVAELADVAIRFSDNTAGNLLLRELGGP +TAITRFARSVGDRATRLDRWETELNSAEPWRITDTTTPYAIGRTYARLVLDDVLNRPDRE +LLTHWLLTNTTSDNRFRLTLPPTWTIADKTGAGSYGTNNNVGIAWTQKGTPVVLAVQTTK +PAQDAAPDNPLVAETARLL---- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0007C55602 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIMPWSPVTEPLIGKMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNSQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012DA5E06 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYNSS +VGGIDKYKTTSITKEQIIPWSPITEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 14-2470-1b TaxID=2023149 RepID=UPI000B9BE5AF +---LEEQFAALEQRFDARLGVFAVDLDSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD +AGTLSLTETRVVEAEDKVPGSAIDW-EAGQAVTLEQLCAAALTRSDNTAGNLLIDAVGGT +GELTAFARSLGDGQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTGGPLSNSSRA +TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLAADGRRILAVVLSRT +ASPDAAAMNELVADAVREIV--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. EPa45 TaxID=1545728 RepID=A0A0G3IPI3_9MYCO +----GQRIAALEKRHNAVVGLYAQNLDSKTEV-AYRDGDLFAMCSTFKAYLSARVLQKAQ +AGELLLTDSVLVEPADLKPNSPRTEPNVGQRMALSDLCAAALQVSDNTAANLLLRTIGGP +PAITAFARSIGDDRSRLDRWEAELNSALPDDPRDTSTPRALGGGIARVLTGDVLDEPHRK +QLEDWMRANTT--SSMRGGLPPRWTTADKTGSGDYASTNDVGIAFGPNGEHVLLAIMTRT +KSDDAEPLRPLIAEVATLVL--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas panacis TaxID=1560345 RepID=A0A1B3ZEY5_9SPHN +--TIEARLKALETRSGGRLGVAILDTATGEMM-GRRLDERFALCSTFKALAIAFTLARVD +RGEENLDRRIYFTQKDLVTPFKATRPHLADGMTVAELCGAAATVSDSTAANLLLAGFGGP +SALTAYLRSIGDHTSRIDRTELALNIVKPGETHDTTSPRAMAATLRHILLGSALSPASRA +RLIEWMMASKDAAQRLRRGLPVGWRIANKPGTWEGVSTNDVGVIFPPDRPPIVVAAYLGG +GHGSVADQEAILSEVARIVA--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio gigantis TaxID=296199 RepID=A0A5M9P4V0_9VIBR +-----QSIQGIESRVSARIGVAVYDSATEQTW-NYKGDECFPMMSTFKTLACANLLYDAE +KKGLDLESKVGIESGDLIVWSPVTKALVDKEISLKDACTATMEMSDNTAANVVLSGIGGF +NGLTEFLRLIGDSKTRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNALSEESKA +QLKTWMMNNKVSDGMIRSILPDGWRIADRSGAGAFGSRAITAIVWSETRAPLIISISLTE +TELTIPERDAVINEISELIFDEy +>[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. LHW63021 TaxID=2231787 RepID=A0A365HC20_9ACTN +--DVRAELRRLEASFQGRIGAFALDTGTGRTV-GHREHERFPGNSTFKAILCGAILARAR +ADPGLLERTLRWTKDDLVAHSPITRKNVEGGMTAAQLCHATITTSDNTAANVLLEQIGGP +PGMTRYYRSLGDPAGRLDRWETELNVWRPGERRDTITPALMARDLHRLTLGPALVPQDRQ +RLVGWLRAATTGAARIRAGLPAGWTVGDKTGTGGHPTASDIAIAWPPSGAPVVIAIYTYR +TAPGGTVDDRVLARTASLLA--- +>[subseq from] Beta-lactamase n=1 Tax=Ideonella sp. MAG2 TaxID=2083017 RepID=A0A523Q3I2_9BURK +--ALPQALAALEQRAGGRLGVAVLDTGNGILL-GHRQDERFGLCSTFKLALAGVVLRLID +QGRLKADQWVPYTQADLQSYAPVAKQHLAQGMTVQALAEATQTTSDNTAANLLLGLMGGP +AGLTQHLRDLGDTTTRLDRLEPAMNLVPVGELRDTTTPSAMARTTAALLTGQALSPASRA +RLADWMVATQTGLKRLRATLPPGWRAGDKTGTAMVDKYNDVAIFWPPGRAPVIVTAYYDT +AKAHRAQDEAVLAEVGRWAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Myceligenerans xiligouense TaxID=253184 RepID=UPI000F4E96A0 +------AFTGLEEAYQARLGVYARDTGTGRHV-AYRADERFPFLSTIKTIAAAEVLEDST +--RADLGTTILYGPGDLVEWSPETEEHAGEGMPLGDVLRAAITASDNTAANLVLDRLGGP +HALEARLRGDGDDVTSVDRPEPELNEWSPGETRDTTTPRAIAAQFQEDVLGDELSEPMRG +FLVRALRDNKTGDDLIRAGVPEGWDVGDKTGSAG-GMRNDLAVLVPPGGDPIILAVYTHT +NDPDAESDPALIAEATRVVVD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Microbispora triticiradicis TaxID=2200763 RepID=A0A372PJN3_9ACTN +--AVRKALRRLEVSFRGRIGAYAIDMATGITI-GYREGERFPLASTFKAFAAGAVLAGTT +-EAELTRQVVRWTAGEVKPHSPQTGRHVADGMTLAALCRAAIVHSDNTAGDLLLKRIGGP +RGLTRYFRSLGDPVSRLDRWEPELNVWSPRERRDTTTPVSIARDLRALTTGGALDAADRS +RLVGWLRGNTTGDARIRAGLPPKWIVGDKTGTGGYGTASDIAVVWPADAAPIILAIYTNR +LTPGGSADDEVVARTATVLV--- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. HPH0547 TaxID=1203592 RepID=S3BQE8_9ACTN +--QTAERFAKIEQKFDARIGVQAVDTGTGRQV-AYHADERFAYASTHKAFTVAAVLDKYS +VDGLD-KKKIAVKASDPVGHAPVTEANVGKKLTLRELCEAAVRQSDNGADNLLVRDLGGP +KKLEAFLEGLGDHVTEVSRYEPDLTEATPGDTRDTTTPRAFTKDLRAVILEKGLGKQERK +LLDSWMLNSPTGTKLIRAGVPDDWKVSDKSGAGRYASRSDIAVVRPPGKAPIVVSVMSKR +TEEDASYDDRLVSEAATVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 14-2483-1-2 TaxID=2023147 RepID=UPI000B9C5A58 +--SAEQNYVDLEARDTARLGVSAVDLGSGYTE-SHRGDERFAFCSTFKVYAVGAVLAAVD +AGALQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLASAALTKSDNTSGNLLIREAGGT +AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTPASRD +RLLAWMTDTQTSDGRFRAGIPEQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT +TSEDSPAMNSLVADATRAAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Listeria newyorkensis TaxID=1497681 RepID=UPI00066A06E1 +-eEAKAELKKLEEKYGATLGIYAVNTADKKKI-SYNDQERFAYVSTYKAIAGGLLLKNLT +--TEQLNKRIYFSKEDLVDYSPVTEKHVDSGMTVKEIINAAMTYSDNTAGNILFQQLDGP +KGYQKELAKIGDKTTQADRLEPELNEAVPGDKRDTTTPEAMANVLSFLTTKGNMASDRLD +YFKQTLIDNTTGDKLIRAGVPAGYTVGDKTGAGSYGTRNDIAVIYPKDKKPLVWVIYSKK +SGKDDEYNDQLIADAAKVLSNYf +>[subseq from] class A beta-lactamase n=1 Tax=Actinokineospora sp. TRM65233 TaxID=2654637 RepID=UPI0012E9E30D +--QATEEFTALESTFGGRVGVYAVDTATGRST-GHRADERFLMCSTAKVLMAAAALRATP +---DLMDRLVRYTPADLVAHSPVTEQHVGTGMTVAALCEATLTVSDNTAANLILSTLGGP +QAVTDYVRTLDDPTTRLDRTETALNTTTPE-GLDTSTPAAFAQTTTALLVDGALPARARD +TLTAWMKASTTGLDLIRAALPPTWTTADKSGSGAQGEVNNVAVTWPPNGKPWVVAVFTAP +DDPESDGSREVVARAAAIALK-- +>[subseq from] Beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=A0A1E5AMR4_ALIFS +--SLTQNIEAIELSSGGYIGVSVLNTETNKIW-EYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIIPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSILPNNWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFNEf +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 06-235-1A TaxID=2022508 RepID=A0A260BN43_9NOCA +---AEQHYLELEDRDTARLGVSAVDLASGSAE-SHRGDERFAFCSTFKVYAVGAVLAAVD +AGDLQLTDTRTVTALDKVPESAVD-WEPGSVVTIADLAAAALTKSDNTSGNLLIREAGGA +DALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLSAASRD +QLLAWMADTQTSDARFRAGVPDQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSTT +TSEDSPAMNTLVADATRTVVDE- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012DAA64C +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLHAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] class A beta-lactamase n=2 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI001366402E +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADILSYAPVAETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDYTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDAAPVVIAVHSSK +DQQDAKADDALISGAAKAAAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A1W0YPC7_9BURK +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAATRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ +PRADAAPRSDVIVSAARIVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A4Q5XYJ6_9PROT +--KASARIAAIEARLGGRIGVSAIDTGSDAEI-NHRAQERFAMASTFKWLLAAGVLKRCE +-EGLNLDAVMYFTPSDLLPTSPVTSAEISATLSVEQLCEAIVTVSDNAAANLLLVPMFGP +EGLTRFLRESGDPHTRLDRVEPELNENRPNDLRDTTVPHAMARTLRRLLTDEVLNANSRA +RLTGWMEKASTGLDRLRAGFPDSWRAGDKTGTGGNGSHNDCCIVWPPGRSPIVIASYLSE +SAAPNIDKAAAHAEIARIIVEEf +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0007C45E14 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIIPWSPITEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHPPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. ERR 942 TaxID=2572676 RepID=A0A560L684_9RHIZ +--SIEEDIRLIETKSGGELGVAVLDTGTNQVV-GHRLDERFALCSTFKVLAIAFVLARVD +QGKEQLDRRVDFSEQDLVLPYKATKPHVGAEMTIDELCKAAAIYSDSTAANLLLASFGGP +AELTDYLRSIGDNVTRVDNVEPKLNIVKPGELHDTTSPRAMAETMKRIILGDMLSPRSRG +LLTDWLVNGQDATQRLRKGVPAGWRIVNKPGTWKGISTNDVGVIWPPHRPPVVVAAYLSH +APGSIESQEAVLADVARRVCD-- +>[subseq from] Beta-lactamase n=2 Tax=Listeriaceae TaxID=186820 RepID=A0A099W3W8_9LIST +-eEANAELKKLEEKYGATLGIYAVNTADKKKI-SYNDQERFAYVSTYKAIAGGLLLKNLT +--TEQLNKRIYFSKEDLVDYSPVTEKHVDSGMTVKEIINAAMTYSDNTAGNILFQQLDGP +KGYQKELAKIGDKTTQADRLEPELNEAVPGDKRDTTTPEAMANVLSFLTTKGNMASDRLD +YFKQTLIDNTTGDKLIRAGVPAGYTVGDKTGAGSYGTRNDIAVIYPKDKKPLVWVIYSKK +SGKDDEYNDQLIADAAKVLSNYf +>[subseq from] Beta-lactamase n=2 Tax=Vibrio splendidus TaxID=29497 RepID=A3UMM7_VIBS1 +-----ESIEQIEFRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE +NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP +NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA +QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TELTIQERDTVINEIGQLIFDAy +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp8963 TaxID=2184547 RepID=A0A3N8LYZ1_9BURK +--AAESPIADIERRHGGRLGVFAVDTGSGRTL-SHRADERFLMCSTFKGILAAQVLARVD +AGNEQLDRLVRYTEQDLIFTSPITKANVARGMSVAALCDAMLVYSDNTAAILLMRSIGGP +AGLTGFARGLGDTVTRSDRYEPDSNDY--GGERDTTTPRAIVTLARSVLLGNVLSPGSRE +RLERGMIDCKPGLNRIRAVLPAGWQAGDRPGTSLQGETNDYALVRPPGRAPLLVAAYYDA +PGVGMDAREAVLREAGTAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Casimicrobium huifangae TaxID=2591109 RepID=UPI0012EB2681 +----ASELATLERKAGGRLGVAILDTGTGRYT-GHRLAERFAMCSTFKLPLAAIILREVD +RGNLRLDQFVPYSKRDIVAHAPITSRQLADGMSIEALARAAQMESDNVAANLLLSLIGGP +AGFTSTLRSLGDSTTRLDRTEPSLNLVTPGDLRDTTTPAAMCQTIAHMLTANWLKPASHD +LLVSWMMATETGLKRVRAGFPQGWRSGDKTGTGMHDKYNDVAIVWPTGKAAVVVSAFYEG +PMRMRDEDQAVLAEAGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis valliformis TaxID=239974 RepID=UPI000584B82A +-----AEFGALEEEFDARLGVYALDTGSGEEV-AFRANERFAFLSTFKALLAGVVLSENS +--LEEMERVVEYGEEDLVDHSPVTEENVGSGMSLLELSDATVRYSDNAAANLLLAEVGGP +EGFGEALVEAGDEVTNPVRWETELNDVGPGEERDTSTPEALAGSLEAFTLGDVLQEDRRE +VLVDLLVRNTTGDELIRAGVPQGWVVGDKTGGAG-GMRNDIGVVWPEGGDPIVVAVLTSR +NEEGAEFDNALVAEATEVVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Paucibacter aquatile TaxID=2070761 RepID=A0A2N8KUD1_9BURK +---FDAACQALEARLGGQIGVFALDTGSQARL-AYRADQRFAMCSTFKLLLAAAVLARID +AGQLRPDQRLRYGPRDLVPHAPVTGALLEGGLTVAALCEAILVHSDNPAANLLLPLVGGP +PGLTRFAREQGDVVTRLDRIEPALNSNEPGDPRDSSTPEAFVGLLDRI-LGSVLSDELRQ +QLLVWMNASETGLRRLRAGAPKDWPAADKTGTGARGAVNDVAVFFPPDRAPLLMAVFMSG +SSQPQADLEAAHAELATRA---- +>[subseq from] Beta-lactamase n=1 Tax=Thalassospira sp. TaxID=1912094 RepID=A0A2E3QB97_9PROT +--ELAYTVTQIENRLDARVGIVLLNTATEETW-SHRPHERFLMNSTVKVPICGAILAQSD +KGALSLSEALPIREADLLSYAPVTSKRVGENMIISDLCLAALDMSDNTASNLLLKRLGGP +DAVTNMFRNTGDTVSRLDRFEPDLNTFVPGDPRDTTTPAAMAATLRKLFLEDALSPSSRV +QLADWTSRGAVTGDLLRVHAPAGWEIFDKSGSGDK-TRNIVALVKPVNEQPWIVYIFISD +ADADFSTRNAALKELSAAVM--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium canariasense TaxID=228230 RepID=A0A100WBX8_9MYCO +---LDQRIGALERRHNAVVGLSAVNLDGPGAV-SHRADESFAMCSTFKAYAAGRILQGVS +RGEFSLDATEFVDPAAVVANSPRTGPRAGTEMTLADLCQAALQVSDNTAANLLLKRLGGP +PAITAYARSIGDERTRLDRWETELNSAIPGDLRDTSTPAALAGGYRALLAGDALAPPQRS +LLEQWMRANET--SSMRAGLPQGWTTADKTGGGDYGSTNDVGIAYGPDGRRVLLAIMTRS +AADDADALRPLIGELATLV---- +>[subseq from] Class A beta-lactamase n=2 Tax=Aliivibrio fischeri TaxID=668 RepID=A0A659J292_ALIFS +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNSQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI00099E87A9 +--QTAERFAKIEQKFDARIGVQAVDTGTGRQV-AYHADERFAYASTHKAFTVAAVLDKYS +VDGLD-KKKIAVKASDPVGHAPVTEANVGKKLTLRELCEAAVRQSDNGADNLLVRDLGGP +KKLDAFLEGLGDHVTEVSRYEPDLTEATPGDTRDTTTPRAFTKDLRAVILEKGLGKQERK +LLDSWMLNSPTGTKLIRAGVPDDWKVSDKSGAGRYASRSDIAVVRPPGKAPIVVSVMSKR +TEEDASYDDRLVSEAATVVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050CA91B +----EQPYSQLEARDTARLGVSALDLTSGSLQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRQ +QLLDWMAGNQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] class A beta-lactamase n=1 Tax=Falsirhodobacter sp. alg1 TaxID=1472418 RepID=UPI0007869C6F +----------------------------------------------FNVLLCDAVLSRVD +AGQKPLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase AST-1 n=1 Tax=Streptomyces hundungensis TaxID=1077946 RepID=A0A387HSS3_9ACTN +---VADELRRLEAAHDVRIGAYAVDTVTGRAV-SYRGHETFPSLSTFKAMVCAAVLDKAR +HEPGLMERVVHWKAGEEVANSPVTAGQGEKGMTVADLCHAAITRSDNTAGNLLLHQIGGP +LGMTHYYRSLGDPISRLDRWEPELNDWKPGERRDTTTPAAMGRDLAWTSLGSALVPADRD +RLNSWLRATVTGGERIRAGLPQDWTVGDKTGTTDYGSAHDIAVAWPKSGHPVILAIYTNH +TTADAAVDNAVIAQTASALA--- +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI0011D1F04C +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGQ +AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSSK +DQQDADADDALISGAARAAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio kanaloae TaxID=170673 RepID=UPI0010BE33C9 +------SIAKIESRISARIGVAVYDSATDQIW-NYKGDERFPMMSTFKTLTCANLFYDHE +SEGLDLESKVGIEPDELIAWSPITKSFVGKEISLRSACAATMEMSDNTAANIVLRSTGGP +SGLTEFLRFMGDRKTRLDHIEPDLNHARPGDQRDTTTPNTMVKTLNELVYGNALSEASKA +QLKAWMMNNKVSDGMIRSILPDGWRIADRSGAGAHGSRAITAIVWSETRAPLIISISLTE +TELAIPERDTVINEIVELVFDEy +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium simiae TaxID=1784 RepID=A0A1X0XWQ8_MYCSI +---FYDRLAELERQYNAYIGLFATNVGSGCTL-AHRDDDPFAMCSTFKAYAVARVLQQVQ +HGELDLQQRIFVDPAALLPNSPVTAPQAGNAMPLAQLCAAALQHSDNAAANLLLAQIGGP +PAITDFARSIGDQRTRLDRWEIDLNTAIPGDPRDTSTPRALGSGIQRLLTGTVLGEAQRS +QLERWLRDNVT--SSMRAGLPPGWITADKTGSGDYGSTNDVGMVYGPSGQRVSLSLMTRS +QSVDADGLRPLIAEVTKSVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces xanthophaeus TaxID=67385 RepID=UPI0004CD28F3 +---LAARLAGLEREHSARLGVFARNTVTGRTV-AYRADERFPMCSVFKTLAAAAVLRDLD +RDGEFLARRIRYTAREAEEYAPVTGRNLAGGMTVEALCAAAVSHSDNLAANLLLRELGGP +RAVTRFSRSLGDRTTGLERWEPELNSAEPWRTTDTTSPRAIGTAYGRLLLGGALEPADRE +RLTGWLLANTTNTDRFRAGLGPDWILADKTGGGNYGVANDVGVVRAPDGPPLVMAVLTTR +PGPQGPRDSALVAATAALLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI00097707F2 +-----QSIEQIESRISARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE +NEGLDLGLKVDIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVATLNELVYGNTLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TKLTIPERDKVINEIGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium gadium TaxID=1794 RepID=UPI0013D6F72E +--SIEASLQGLEQRHNAAIGLFASNLLSNKTV-AHRAQDQFALCSVFKGYASARVLQMAQ +HGELSLDDRMFVDPAQILPNSPVTGPRAGSEMTLAELCQATLQQSDNAAANLLLSRIGGP +PAITAFARSIGDRQTRLDRWETELNSATPGDPRDTSTPEALGWGYRAMLEGDVLAPPQRR +LLEDWMRANQT--SSMRAGLPPDWTSADKTGSGDYGTTNDVGIAYGPDGQRVLLAIMTRS +QADDTANMRPLIGETTALV---- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas putida TaxID=303 RepID=A0A1X0ZNF5_PSEPU +-qQVEQDAKVIEASLSAHIGISVLDTQTGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGEINPKSTIEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNAAANIILNALGGP +ESVTDFLRQIGDKETRLDRIEPELNEGKLGDLRDTTTPNAIVNTLNELLFGSTLSQDGQK +KLKYWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEAQSPIIVSIYLAQ +TEASIADRNDAIVKIGRSIFEVy +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI00030048C4 +--SLTQNIEAIELSNGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS +VGGINKYKTTSITKEQIIPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP +RSLTQFLRAIGDDKTRLDRIEPKLNEAKNGDKRDTTTPVAMSETLNTLLFGNTLNPQDKQ +TLKSWMMNNKVSDPLLRSILPSDWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000D107959 +------------------------------------------ICSTSKVIAVAPVLNKSE +TEPNLLNQRVENKKSVLINYKPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium litorale TaxID=758802 RepID=A0A4R8J419_9MYCO +-------LEALERANGTVIGVFGVNLETGRTV-AHRAQDTFAMCSTFKAYLAAHVLQLVG +RGERSLEQRLPVTAADIKPNSPRTEPRVGGDMTIAELCQAILQVSDNAAANILLGNIGGP +PAVTAFARSIGDPRSRLDRFEIELNSAVPGDPRDTSTPEALAGGFRAFLAGDVLAPPQRQ +LLGDWMRANET--SSMRAGLPVGWTTADKTGSGDYGTTNDVGIAYGPKGQRVLLAVMTRS +AAPDAENNRPLVGEVTATVF--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. WY10 TaxID=1920667 RepID=A0A1J0U730_9MYCO +---VDQRIAALEKRHNALVGLYAQNLESKVEL-AHRDGDLFAMCSTFKAYLSARVLQKAQ +AGELRLTDTVVVEPAELKPNSPRTEPNAGKPMTLSDLCAAALQVSDNTAANLLLRVIGGP +PAITAFARSIGDDRSRLDRWETELNSALPGDPRDTSTPRALGGGIARVLTGDVLDTTHRT +QLDDWMRANTT--SSMRGGLPPDWTTADKTGSGDYASTNDVGIAFGPNGERILLAIMTRT +QSDDAEPLRPLIAEVAALA---- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012D99583 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIIPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSQTLNALLFGNTLNSQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDIAERNQVIVEVGNAIFKEf +>[subseq from] Beta-lactamase n=4 Tax=Mycobacteriaceae TaxID=1762 RepID=A0A1A0M3J5_9MYCO +------NFADLEDRYQALIGVYAVDLESSATV-EHRADERFAMCSTFKAYAAARILQMAT +AGKANLDAMVPITAGDIVVNSPVLSEAVGARMALREICAAALSQSDNAAGNIMLRTIGGP +SALTDFARSIGDSQTRLDRWEPALNEAAPGDLRDTTTPRALCGGYRAILAGDALSGAAQF +QLRRWMEETATSTRRFRAGLPEGWTSADKTGGGDYGSTNDAGMLIGPKRERVMLTVLVRT +RTRDAGPFNEAIAESVRSVL--- +>[subseq from] Beta-lactamase GES-5 n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0X9L5U5_9BACT +---FKTDLEKLEREKAAQIGVAIVDPQGQIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQDRD-YAVAVYTTA +PKLSAEQRDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Kitasatospora sp. OK780 TaxID=1882771 RepID=A0A2N0K2P9_9ACTN +-----AGLEQLEREHAARLGVFALNPATGRTV-LYRADESFPLCSVFKGVAAAAVLRDLD +RDGEALARRIHYTRADVDAYTPDTGRNLAQGMTVEQLCAAAVGHSDNLAGNLLLRELGGP +TAITRFCRSIGDGRTRLDRWEPDLNSAEPWRTTDITSPRAIGTTYARLLLGDVLPPRDRQ +RLTGWLIANTTNTARFRAGLPADWILADKTGGGNYGVANDVGVVRPPDGPPLVMAVLTTT +LAAAGPSDNVLVQRTAELLA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 05-2254-4 TaxID=2022492 RepID=A0A260MPN7_9NOCA +--------LDLEARDTARLGVSAVDLASDSTE-SHRGDERFAFCSTFKVYAVGAVLAAVD +AGELQLSDTRTITAADKVPESAVD-WEPGSVVTIADLAAAALTESDNTSGNLLIREAGGT +AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTEASRM +QLLEWMANTQTSDARFRAALPAGWTSADKTGTGSYGVSNDAGLLLGPDGQRILVVVLSAT +TSEDSPAMNSLVADATRQVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012D9E23F +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIIPWSPITEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNSQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=R4T4Q4_9PSEU +--------------------MYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP +--IAELDRTVTYGKQDLVVNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP +EGLNAVFRGIGDTTSHADRIEPELNDTFPGDLRDTSTPRALAVSLRAFALGDALPEDKRK +ILVDMMRANTTGDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVVSVLTDR +PDKDAEIDNKLLADATAAAVK-- +>[subseq from] Beta-lactamase n=1 Tax=Atlantibacter hermannii TaxID=565 RepID=Q84EY4_ATLHE +---MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ +KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLAGP +DAVTQFMRGIGDHVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTSPPLISANRA +TLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ +TEASMKMANETTAEIGKQLF--- +>[subseq from] Beta-lactamase n=1 Tax=Lysobacter sp. yr284 TaxID=1761791 RepID=A0A1H3PLR7_9GAMM +--ALRERLAAIEQRSGGRLGVAVLDTADGRHW-SMRGDERFGMCSTYKLPLVAAVLHKAE +LGQIDLNARIAVPAAALVPNSPATAALARSGASVARLCEASLTVSDNTAANLLLPLVGDP +AGLNGFLRGLGDPVTQVERTPGAPLP--GGDARDVTTPDAMLATMRAVLLGDALNAASRQ +RLSDWLLAATTGPRRLRAGLPQGWRVGHKTGTSRD-SANDIAIVWPGRRAPVLIAGYFTG +ARGDDASRDAVLADAARALATHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus pyridinivorans TaxID=103816 RepID=UPI000E70BD9A +---VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA +EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP +EAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGSGLPAPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Psychromonas ossibalaenae TaxID=444922 RepID=UPI00036B7459 +---LVKKIKQIENELDARVGVSIYDAGNQKSW-DYKGDLRFPLMSTFKSLACAKLLADVD +GGHISLQSSIVIKQSSLVTYSPVTQNYVDKEFTLYQACSAAMLMSDNTAANIVLESINGP +KGLTAFMRKIGDQVTSLDRIEPALNEALPGDLRDSTSPNAINHSLHKLLFGNELSEQSKK +QLKQWMTANKVADNLLRSVLPGSWQIADRSGAGGNGSRGITAVVWQDKQAPFLISIYITQ +TDASFALRNKAIVEIGNEIFN-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium sp. NCC-Tsukiji TaxID=2185272 RepID=A0A391PG29_9MYCO +------NFADLEDRYQALIGVYAVDLESSATV-EHRADERFAMCSTFKAYAAARILQMAT +AGKANLDAMVPITAGDIVVNSPVLSEAVGARMALREICAAALSQSDNAAGNIMLRTIGGP +SALTDFARSIGDSQTRLDRWEPALNEAAPGDLRDTTTPRALCGGYRAILAGDALSGAAQF +QLRRWMEETATSTRRFRAGLPEGWTSADKTGGGDYGSTNDAGMLIGPKRERVMLTVLVRT +RTRDAGPFNEAIAESVRSVL--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio mytili TaxID=50718 RepID=A0A0C3EDB5_9VIBR +--HLNENISNIEQQISGRIGVSIWDTQNDSHW-DYRGDERFPLTGTAKTLACATMLESMD +TGQLDKNATSKLVKENMVMWSPVMEKMTGESVRVEHACEAAMLMSDNTAANLVLSSVGGP +DAVNLFLRRVGDNTTRLDRQEPEINEAKPGDVRDTTTPNAMVNTLESLLEGKVLAYESRL +QLRIWMQDNKVSNALIRSVLPQGWSIADRSGQGGHGSRSVNAVIWKEDHKPIYITIYVTD +TELSLQARDQLVAQISQLILEPy +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 / 3849) TaxID=1122247 RepID=K5BK13_MYCHD +---VTTQLAELERRHAAHIGVYARNLASGRTI-AHRSGEPFAMCSTFKTYAAARVLQLVD +RGEANLEETMFVDPAAILINSPVTAERAGGVMTLSELCQAALQRSDNAAANLLLHRIGGP +PAITAFARGIGDDRTRLDRWEPELNAAVPGDPRDTSTPEALAGGYRALLDGEVLSPLRRG +LLDAWMRANQT--SSMRAGFPPGWTSADKTGSGDYASTNDVGIAYGPAGERLLLAFMARS +ARPDAEGLRPLIGELAALIV--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 1245805.9 TaxID=1856862 RepID=A0A1A3C6T4_9MYCO +----YKRFADLEREFDGKIGVYAVDTNNGELI-AHRADERFPLQSTIKLLGVAALLKRGG +ADSNLLQEQVHYSERDLTTWSPVTRKNIAGGMTLEALAEAAISDSDNTAMNLITKALGGP +AEVERFAHSVGNQKYNVEHYEGQLNSD-PHSQVDTSTPKDMATSVQALTVGDALAPPQRA +QLLGWMRDNTVGYKRIRAGAPLGWLVADKTGSGAYGIANDIGIVASPYCKPIVLAIYTVQ +NRRDATAREDIVATATGAILGQf +>[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea candida TaxID=359159 RepID=UPI000A00CFC6 +--RVTRELRALEASFQGRIGAYAIDTATGRTV-GYRSGERFPLLSTFKAPLCAAALHRAR +AEPGLMDKVVTWTTGDLKRNSPTTEKHVEDGLSVSRLCEAAITESDNTAANMVLKQIGGP +AGLTRYFRSLKDPVSRLDRWETELNDWTARERRDTTTPAAAARDLRVLTSGDALHAKDRK +RFNAWLIANKTGDARIRAGLPKTWTIGDKTGTNGIGGANDIAVAWPSSQAPIILAVYTNR +EV--AAADDAAVAKTATILA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=G8HDC7_9BACT +--------------LGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPDTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAG--------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A2W6VG55_SPHSX +-----ANLQALESIAGGRLGFALLDTGTGKIM-GHRLDERFGLCSTFKLPLAALVLRAAD +KGELKLDQLIPISKADLVPHAPDTASKVGQGMTIKELARAAQVSSDNVAANLLIKKLGGP +AGVTKRLRALGDSVTRLDRMEPELNRVIGDDPRDTSSPRAMAETVALLMTGNHLSPASQA +QLKRWMIETQTGKRRLRAVAPPGWTAGDKTGTGVRNRVNDVAIFWPPKGAPLVAVAFYEA +PGTTRPQDENVLVQAMQI----- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0007C5C786 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPIAMSQTLNALLFGNTLNSQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 / 3849) TaxID=1122247 RepID=A0A3P3ZYS9_MYCHD +---VTTQLAELERRHAAHIGVYARNLASGRTI-AHRSGEPFAMCSTFKTYAAARVLQLVD +RGEANLEETMFVDPAAILINSPVTAERAGGVMTLSELCQAALQRSDNAAANLLLHRIGGP +PAITAFARGIGDDRTRLDRWEPELNAAVPGDPRDTSTPEALAGGYRALLDGEVLSPLRRG +LLDAWMRANQT--SSMRAGFPPGWTSADKTGSGDYASTNDVGIAYGPAGERLLLAFMARS +ARPDAEGLRPLIGELAALIV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus pyridinivorans TaxID=103816 RepID=A0A419ZHR4_9NOCA +---VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA +EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP +EAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGSGLPAPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI001365DBA4 +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADILSYAPVAETRVGGTMTLRELAEAAMTRSDNTAANLLLEAIGGP +AELDTALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDVDERA +LFTGWLKATQTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSAK +DQQDADADDALISGAAKAAAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 05-2255-1e TaxID=2022495 RepID=A0A260LLR8_9NOCA +----EQPYSQLEARDAARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRQ +QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium tusciae TaxID=75922 RepID=UPI000D1D1342 +--SIEASLQGLEQRHNAAIGLFASNLVSDKTV-AHRAQDQFALCSVFKGYASARVLQMAQ +HGELSLDDRMFVDPAQILPNSPVTGPRAGSEMTLAELCQATLQQSDNAAANLLLSRIGGP +QAITAFARSIGDRQTRLDRWETELNSAIPGDPRDTSTPESLGVGYRAMLEGDVLAPPQRR +LLEDWMRANQT--SSMRAGFPPDWTSADKTGSGDYGTTNDVGVAYGPDGQRVLLALMTRS +QADDAENMRPLIGEITALVL--- +>[subseq from] Beta-lactamase n=1 Tax=Marinobacter subterrani TaxID=1658765 RepID=A0A0J7M4U6_9ALTE +---------------------ALMNCSTGAVA-SHRGDERFLFNSTGKLFIAAAVLAQVD +RGDAALDLRLVVSESDLGGWTPITEKHLGEPMTVAELCQAVVAWSDNAAANVLVRFVGGP +EAVTAFLRSIGDDVTRLDRYEPELNEDHEGDKRDTTTPLAMMKTLQRLLLGEALSPSSRH +QLAAWMIEGKTGDARLRAGMPSSWLIGEKTGTNGVGNANDIGIAWPADRGAVVAVAYTFG +PKASKEQRDDVIAMIGAMA---- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium poriferae TaxID=39694 RepID=UPI0013D5004A +-----PRIEALERREGIIVGLHAVDLPTGRRL-AHRAKDRFAMCSTFKGYAAAAVLSRVD +RGLLALTDTVTIAPAELVTYSPVTEPRLGQPMTLAELCQAAVQQSDNSAANALLRVLGGP +PAITEFARSIGDEVSRLDRWETALNSAVPGDLRDTSTPVALGTGYRALLAGDALGGSSRQ +TLQDWMQANET--SSMRAGLP-GWSTADKTGSGDFGTANDVGIAYGPQGQQLLLSIMTRS +AGPEAPSRRDLIGELAALVA--- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia unamae TaxID=219649 RepID=A0A328X5A9_9BURK +----ESPFAAIERRSGGRLGVFAVDTGSGATL-AWRADERFLMCSTFKGMLAAQILARVD +AGHERLDREVRYTERDLIFTSPVTKANLAQGMTVGALCKAAVEVSDNTAAILLMRGAGGP +AALTRFMRDIGDDVTRSDRYEPASNQR--DGELDTTTPHAIVESARKILLGDVLGAQPRQ +QLEDWMIASTPGRNRIRASLPPDWRAGDRPGTSVEAETNDYAIVRPPGRAPLVVATYFDA +PGLDMARREAVLREAGAAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia grenadensis TaxID=931537 RepID=UPI0009FFAD75 +--DLSNTLMALQAKYNVLFGIAAVDTRGGRTF-EWNADDRFALCSTFKVYAVAAILRLAE +RKELDLNDKVAITRQDIVMSSPVVSDHVGELMSYYELSRAALVRSDNTAANLLLRRLGGP +RAVTEFARTVNDSQTRLDRWEPELNEARAGDPRDTGTASALAAGYRKLVLGDGLSTEYRR +MLTSWMRSSVTSRQRLRAGLPVGWVAADRTGSGAYGTANDAGVVWSPAGTSLVLVVFSRS +TTPMAAGADAAVADATAAVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis ganjiahuensis TaxID=239984 RepID=UPI000476E528 +----AAEFEALEEEYGSQLGVYALDTGSGAEV-AFQEGERFAFASTFKALLAGVVLSENS +--LEEMERVVTFDEGVLVSHSPVVEENLDSGMSLLELCDATVRFSDNAAANLLLEEIGGP +EGFTESLGETGDDVTILERYEVEMSSAVPGEVRDTSTPKAMAGSLEAFALGDVLPEDRRE +VLVDLMVRNVTGDDLIRAGVPEGWVVGDKTGNGGYGTRNDIAVLWPEEGDPIVLAVMSSV +GVEDAEHDDALIAEATEVVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000F04ADC5 +----------------------------------------------FKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLPSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Beta-lactamase n=1 Tax=Kitasatospora cheerisanensis KCTC 2395 TaxID=1348663 RepID=A0A066YSA8_9ACTN +--------------------MYVLDTGSGREV-AHRADERFAFASTSKALVGGALLRRAS +--DADLERVVTYRQQDVLAWAPVTSQHLATGMKLRDLLAASLDHSDNTAANLVMAEVGGP +AAVQQALRDLGDSTTDVSRTEPALNEAVPGDRRDTSTPRVLADDLRQYLLGDVLPPARRQ +LLTDLMLANTTGGPYIRAGVPAGWQVADRTGNGGYGTRNDLAVVWPGGGKPLVVAVLSDR +SRPDAPSNDTLLAEATEAALD-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium tusciae TaxID=75922 RepID=A0A1X0JJZ3_9MYCO +--SIEASLQGLEQRHNAAIGLFASNLVSDKTV-AHRAQDQFALCSVFKGYASARVLQMAQ +HGELSLDDRMFVDPAQILPNSPVTGPRAGSEMTLAELCQATLQQSDNAAANLLLSRIGGP +QAITAFARSIGDRQTRLDRWETELNSAIPGDPRDTSTPESLGVGYRAMLEGDVLAPPQRR +LLEDWMRANQT--SSMRAGFPPDWTSADKTGSGDYGTTNDVGVAYGPDGQRVLLALMTRS +QADDAENMRPLIGEITALVL--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 06-221-2 TaxID=2022514 RepID=A0A260BSG7_9NOCA +----EQPYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRE +QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGKKILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 1R11 TaxID=2559614 RepID=A0A4Y8YZF9_9NOCA +----EQPYSQLEARDTARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLTQASRE +QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus pyridinivorans TaxID=103816 RepID=UPI00110DD28F +---VDERLREIEDRYAVRLGVVAQSPGTGRVH-TYRADERFAICSPFKVYAAAAILRLEA +EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP +GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. Soil538 TaxID=1736391 RepID=A0A0Q9JRW0_9MYCO +-----DRIEALGRRHNAEIGLYATDLESGREI-AVRDGDSYALCSTFKAYASAAILQRAQ +HGRLGLTDAVRVERADIQPHSPVTEPRVGATMTLAELCQAALQQSDNAAGNLLLRTLGGP +PAITEFARGAGDDRSRLDRWETALNSAVPGDPRDTGTPRALGTGFRAVLTGDVLDAAHRQ +QLENWMRANET--SSMRAGLPDGWSTADKTGSGGYGTTNDVGIAYGPQGQRWLLSIMTRA +AGPDAPNLRPLIGEIASVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Aeromicrobium erythreum TaxID=2041 RepID=A0A0U4D7H5_9ACTN +---FSADFADLEQEYDARLGVYAIDTGTGQVV-EHRAGERFAYASTIKAIAVGALMHEKP +--RSVLDQTVQISEDDLVDFSPQVEKALEAGLTVREVADAAVRYSDNTAGNLLFDLLGGP +EELQGVLREIGDRTTKVSRIEPDLNEATPGDDRDTTTPEALATDLRRLTLKDVNDGYARA +FLTDLMVRNTTGDDLIRAGVPDTWEVADKTGAAKYGTRNDIAILRRAEGAPIVIAIMSSK +DDQDAEADDDLVADATRVAVAGf +>[subseq from] Beta-lactamase n=2 Tax=Marinobacter TaxID=2742 RepID=A0A1M2URI1_MARHY +-qQVEQDAKVIEASLSAHIGISVLDTQTGESW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGEINPKSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNAAANIILNALGGP +ESVTDFLRQIGDKETRLDRIEPELNEGKLGDLRDTTTPNAIVNTLNELLFGSTLSQDGQK +KLEYWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEAQSPIIVSIYLAQ +TEASIADRNDAIVKIGRSIFEVy +>[subseq from] Beta-lactamase CARB-4 n=4 Tax=Gammaproteobacteria TaxID=1236 RepID=BLC4_PSEAI +-qQVEQDAKVIEASLSAHIGISVLDTQTGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGEINPKSTIEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNAAANIILNALGGP +ESVTDFLRQIGDKETRLDRIEPELNEGKLGDLRDTTTPNAIVNTLNELLFGSTLSQDGQK +KLEYWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEAQSPIIVSIYLAQ +TEASIADRNDAIVKIGRSIFEVy +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. JG-3 TaxID=1305835 RepID=UPI0004872312 +----EQPYSQLEARDAARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLTRASRQ +QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SII5_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWV----------------------------------- +----------------------- +>[subseq from] Beta-lactamase GES-2 n=2 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q93F76_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMNDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. 1245805.9 TaxID=1856862 RepID=UPI0009ED2FF8 +-----KRFADLEREFDGKIGVYAVDTNNGELI-AHRADERFPLQSTIKLLGVAALLKRGG +ADSNLLQEQVHYSERDLTTWSPVTRKNIAGGMTLEALAEAAISDSDNTAMNLITKALGGP +AEVERFAHSVGNQKYNVEHYEGQLNSD-PHSQVDTSTPKDMATSVQALTVGDALAPPQRA +QLLGWMRDNTVGYKRIRAGAPLGWLVADKTGSGAYGIANDIGIVASPYCKPIVLAIYTVQ +NRRDATAREDIVATATGAILGQf +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A2W4X6F6_9PROT +------RFAAIEARIGGRVGVAAWNTATNAWL-GHRQHERFAMCSTFKWALAAHMLWIGQ +RQPDFLGSRVLYREADLLSYAPVTRERFGSGMTVEYLCEAAVGLSDNTAANLLLEAAMGP +EGFTRFLRANGDAVTRLDRYEIELNDVPPGDERDTTTPEAMARTLKRFLVDDVLTPAHRE +KLIGWMVDSPTGLQRLRAGFPADWRVGDKTGTWNHNATNDVAIAWPPNRAPIVVAAYLSA +STADVAARNAAHAEIARIITEAw +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium agri TaxID=36811 RepID=A0A2A7MYU9_MYCAG +----HQRIEALQRQHNTKIGVYAVDLASGRTV-SHLDGEMFAMCSTFKGYAAARVLQMVQ +NGELTLDRQVYVDPKAALPNSPRTAPNSGGQMSLADLCAAAVQVSDNAAGNLLLQTIGGP +SAITHFARSIGDERTRLDRWEIELNSATPGDPRDTSTPRALGGGYRALLTGDALAPPQRQ +QLEDWMRANET--SSIRPALPEGWTTADKTGNGDYASTNDVGIAYGPQGERLLLAIMTRT +QTPDAPNNRPLIGEVTKALV--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 15-2388-1-1a TaxID=2023142 RepID=A0A260RZH6_9NOCA +---AEQNYLDLEDRDTARLGVSAVHLDSDSTE-SHRGDERFAFCSTFKVYAVGAVLAAVD +AGTLQLSDTRTITAEDKVPESAVD-WAPGSIVTIADLASAALTESDNTSGNLLIREAGGT +AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTAASRE +QLLAWMADTQTSDARFRAALPAGWTSADKTGTGSYGVSNDAGLLLGPDGQRILVVILSAT +TSEDSPAMNSLVADATRQVVQQ- +>[subseq from] PSE-1 n=1 Tax=Gallibacterium anatis TaxID=750 RepID=A0A161HRT0_9PAST +-nRLNKMLKVIEASLSAHIGISVLDTQTGEYW-DYNGNQRFPSTSTFKTIACAKLLYDAE +QGEINPKSTIEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNAAANIILNALGGP +ESVTDFLRQIGDKETRLDRIEPELNEGKLGDLRDTTTPNAIVNTLNELLFGSTLSQDGQK +KLKYWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEAQSPIIVSIYLAQ +TEASIADRNDAIVKIGRSIFEVy +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia aspalathi TaxID=1324617 RepID=A0A1I7E3E4_9BURK +------PLADIERRNGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLSRVD +AGKEDLARLVKYTGKDLIFTSPVTKAHVAEGMSVGALCQAIVEVSDNTAAVLLMRSVGGP +AALTQFVRGLGDTVTRSDRYEPESNKN--SGVLDTTTPRSITNSASKILLGNVLSPQSRT +QLENWMIACKPGLNRLRAALPPDWVAGDRPGTSVEEETNDYAIVRPPGRAPLLIAAYYDA +PALDMPAREAVLREVGAVFV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Vibrio pectenicida TaxID=62763 RepID=A0A427U5F7_9VIBR +-------IEAVSTSLGARVGVFVSNANTNQQW-HYNGNQRFPTASTFKVLACAAALDKGA +-----LSTAVKITEKDLVEYSPVTEKYINNTMTYNQLCHATITTSDNTAGNLILRYIGGP +EGLTQFLRGTGDNVTLMSRWEPELNQGTPGDKRDTTTPHAINRTLGILLFGDVLSQSKQQ +KLLQWMKQDQVADDLLRSVLPKTWQIGDKTGAGGHGSRGIIAVLIPPNSEPVLVSIYLTE +SQTTIKQLNKAIATIGSAIIK-- +>[subseq from] Class A beta-lactamase GES-41 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A4V1E803_PSEAI +---FRTDLEKLEREKAAEIGVAIVDPQGQIVA-GHRIEQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGRDMIVEWSPAAERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTPTSTH +TIERWLIGNQTGDATLRAGFPKDWVIGEKTGTCANGGRNDIGFFKAQDRD-YAVAVYTTA +PKLSAEQRDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=A0A2S1XWT4_VIBAL +-qQVEQDAKVIEASLSAHIGISVLDTQTGESW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGEINPKSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNAAANIILNALGGP +ESVTDFLRQIGDKETRLDRIEPELNEGKLGDLRDTTTPNAIVNTLNELLFGSTLSQDGQK +KLEYWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEAQSPIIVSIYLAQ +TEASIADRNDAIVKIGRSIFEIy +>[subseq from] Beta-lactamase n=1 Tax=Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5) TaxID=272568 RepID=A9HJJ4_GLUDA +-------ISDYENGTGGHIGLYAENVKTGAKL-TWRARERFVMCSTVKASLAACVLSRVD +RGRDRLEDIIPYSASDIQDYAPVAKANLARGMSVGDMCQAAVEQSDNTCANILLARIGGP +SALTAFWRGIGDRETRLDDPEPYLNRTPPGGVRNTTTPASMATIMRSLVLGRVLSDASRA +IFTRWLVGCRTGDDRLRAGLPPHWVIGDKTGNNGRDAAGDIAVVWPERDVPIILCVYTRG +GSPTQQQFRTAFAGIARVV---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=UPI0011A62ED0 +---VDKRLKEIEDRYAVRLGVFAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLES +EGSLRLDETFPIDPDDIVVNSPVTSEHQGRVLPLDRLCEAALTRSDNTAGNLMLHRIGGP +EAVTAFARSVGDEVTRLDRWEPELNEAARGDERDTTTAAGLAHGFREVLLGSGLPDPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPMVLAILSDS +TTGDP------------------ +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia oxyphila TaxID=614212 RepID=UPI00048838FD +--AAESPFADLERRNGGRLGVFAIDTGSGRTL-AWRADERFLMCSTFKGLLAAQILARID +AGQERADRQVRYTEQDLIFTSPVTKAHVAHGMTVGALCEAAVEVSDNTAAILLMRSAGGP +EGLTQFVRGLGDSVTRSDRYEPHSNQY--SGALDTTTPRAIAQSARKILLGNVLSMQSRQ +QLEDWMIASTPGRARIRAALPADWRAGDRPGTSVERETNDYTIVRPPGRAPLVVAAYYDA +PGRDMARREDVLRDAG------- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 06-1460-1B TaxID=2022501 RepID=UPI000B9ACAC6 +----EQPYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRQ +QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=UPI000A1C9182 +---VDERLKEIEDRYAVRLGVFAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLES +EGSLRLDETFPIDPDDIVVNSPVTSEHQGRVLPLDRLCEAALTRSDNTAGNLMLHRIGGP +EAVTAFARSVGDEVTRLDRWEPELNEAARGDERDTTTAAGLAHGFREVLLGSGLPDPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPMVLAILSDS +TTGDP------------------ +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012D9ACBD +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIIPWSPITEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLIALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A8HNR5_KLEPN +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKPAA---------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1W5MZZ2_9BACT +------PFLAIERRSGGQIGVAAFNVRTGAAL-TYRSDERFAMCSTFKWLLGGLILQRVD +RGIEDLERRLPFDSSDLVFHSPVTEAHADGRMSVGDLCEATIKTSDNTAANILMETLGGP +SGFTQSLREMGDRVTRLDRLEPYLNENAPGDLRDTTTPMAMANLMREILFGTRLSDGSKD +MLHDWMIGASTGLDRLRAGFPEGWRGGDKTGTSSNRANNDVGFALPPAGDAIIIASYTNV +PDPLDGAANAVHSEIARHVI--- +>[subseq from] Beta-lactamase n=1 Tax=Psychromonas sp. Urea-02u-13 TaxID=2058326 RepID=A0A2N1A8C2_9GAMM +---LTEKIKSVEKKLGARIGVAVYDTQSKALW-SYKGDTRFPLMSTFKTLACAKLLADAE +SGIVDINSTTMIDADSLITWSPVTEKRVGETMSLKQACTATMVMSDNTAANIVLAGIDGP +SGLTKFMRAIGDDVTRLDRIEPYLGEAIDGDPRDSSTPNAMVASLNRLLFAGVLSTEGKV +QLKQWMMDNKVSDALLRSVLPQGWSIADRSGAGGYGSRGITAVVWSEQRPALIISIYLTQ +TTASFAQRNDTIATIGKHIFTVy +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia aspalathi TaxID=1324617 RepID=UPI000B87BFDC +------PLADIERRNGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLSRVD +AGKEDLARLVKYTGKDLIFTSPVTKAHVAEGMSVGALCQAIVEVSDNTAAVLLMRSVGGP +AALTQFVRGLGDTVTRSDRYEPESNKN--SGVLDTTTPRSITNSASKILLGNVLSPQSRT +QLENWMIACKPGLNRLRAALPPDWVAGDRPGTSVEEETNDYAIVRPPGRAPLLIAAYYDA +PALDMPAREAVLREVGAVFV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. (strain SPB074) TaxID=465543 RepID=B5GAH4_STRSH +----AAEFTALERAYGAHLGVHAVDTGSGREV-AWHADTRFPYNSTFKALLCGAVLKKHG +--TGAMDHVLRYSREDLVANSPVTEKHVATGMSRDALCDAAIRYSDNTAANVLLTELGGP +RALGALVRETGDRLTRMERVEPLLSRWTPGETRDTTTPRRLTADLRAYTLGDVLTTPRRQ +RLNGWLSRNTTGDATIRAGVPKGWKVADKTGTGSHGARGDIAVIRPPGRAPLVLTLLSYR +EERTAEADDRLLAEATRVVVR-- +>[subseq from] Beta-lactamase GES-13 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=D1MIX9_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMNDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus rhodochrous J3 TaxID=903528 RepID=A0A1X7KG93_RHORH +---VDERLKEIEDRYAVRLGVFAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLES +EGSLRLDETFPIDPDDIVVNSPVTSEHQGRVLPLDRLCEAALTRSDNTAGNLMLHRIGGP +EAVTAFARSVGDEVTRLDRWEPELNEAARGDERDTTTAAGLAHGFREVLLGSGLPDPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPMVLAILSDS +TTGDP------------------ +>[subseq from] Beta-lactamase n=1 Tax=Henriciella sp. TaxID=1968823 RepID=A0A2D8YA11_9RHOB +-------IEALELGHEGRFGVAAVTSGGEDLV-SHRADERFAMCSTFKWLMAGLVLQEVD +SGRETLERRVPIAGEDLVFHSPVTSQHVGAQLPVSQLCAATIGTSDNTAANLLLAGLGGP +DGFTQRLRASGDMVTRLDRMEPALNENEPGDPRDTTTPRAMARNLDRFLFGSQLSAPSRD +MLRTWMIAADTGLDRLRAGLPAGWTSGDKTGTSSNGANNDVAFSIPPDAKPLIIASYLNL +PDPVSPEANALHAKIAGLV---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=UPI00132EF12E +---VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA +EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP +EAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGPGLPAPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium moriokaense TaxID=39691 RepID=A0A370CTK5_9MYCO +--AVNDRIEALQRQHSAKIGVYAVDLASGRTL-SHLDNEPFAMCSTFKVYAAARVLQMVQ +NKALDLNRQVFVDPAQSALNSPRTAPNSGGWMSLADLCAAAVQVSDNGAGNLVLQTIGGP +GAVTDFARSIGDDRTRLDRWEIELNSAAPGDPRDTSTPRALGEGYRSVLAGTVLAPPQRG +QLEDWMRANQT--SAVRGGLPAGWTTADKTGSGDYGSTNDVGIAYGPDGQRVLLAIMTRS +RTDDAPNNRQLISELAQAVV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Telmatospirillum sp. TaxID=2079197 RepID=A0A6A8QMB2_9PROT +--TFEARLKDLEARSGGRLGVALLDSATGQIV-GNRLDERFALCSTVKALVVAFVLSRVD +RDEESLERRIVFTERDLVIPFKATRPHVGPEMTVGALCEAAITVSDSTAANLLLQSVGGP +AALTAHLRSLGDPVTRLDHVELALNIVKPGETHDTTTPRAMAETMRRLLLGDALSDASRG +RLTNWMVAATAATRRLRAGLPAGWRIANKPGTWEGISTNDAGVIWPPGRAPVVVSAYLGE +APGSTETQEGVLAGVARIVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis subsp. michiganensis TaxID=33013 RepID=A0A251Y021_CLAMM +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAMPIEAADILSYAPVTETRVGGSMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTCATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSAK +DQQDADADDALISGAAKAAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium neglectum TaxID=242737 RepID=UPI000BFEB732 +--SVDASIQGLEHQHNAFIGIFATNLVSGKTV-AHRAQDPFAMCSTFKGYASARVLQMAQ +HGELSLDDTMFVDPASILPNSPLTEPRAGGEMTLAELCQAALQQSDNAAANILLTRIGGP +PSITAFARSIGDERSRLDRWEIELNSAIPGDLRDTSTPEALGGGYRALLDGDVLAPPQRG +LLENWMRANQT--SSMRAGLPPGWTTADKTGSGDYGSTNDVGIAYGPDGQRVLLAILTRS +QANDAENMRPLIGEVTALVM--- +>[subseq from] Class A beta-lactamase n=1 Tax=Gammaproteobacteria bacterium CG_4_9_14_3_um_filter_38_9 TaxID=1974022 RepID=A0A2M8A1Z2_9GAMM +--SVSQKLHQLEIKDHVEIGLSAIETYNNTQI-NYHANQRFPMDSTSKLMTVSAILKKSE +GDPTLLKQKIFFTIKEVKKYAPITSKHIQSGMTVSDLCAAALKYSDNAAVNQLMKILGGP +NKVTQFARSIGDNQFLLTRWEPELNSAIPYDKRDTTAPSAMAESVQKLVLGNALRKSQRQ +LLQEWLKHCKTGNHRIRSGVPAHFIVADKTGTGGYGSIGDIGVVWRPHASPIVLAVYVRQ +NEKNAHTSDKVIAQATKITIN-- +>[subseq from] Beta-lactamase n=1 Tax=Zobellella taiwanensis TaxID=347535 RepID=A0A2P7QX08_9GAMM +-qQVEQDAKVIEASLSAHIGISVLDTQTGESW-DYNGNQRFPLTSTFKTIACAKLLYDTE +QGEINPKSTVEIKEADLVTYSPVIEKQVGQAITLDDACFATMTTSDNAAANIILNALGGP +ESVTDFLRQIGDKETRLDRIEPELNEGKLGDLRDTTTPNAIVNTLNELLFGSTLSQDSQK +KLEYWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEAQSSIIVSIYLAQ +TEASIADRNDAIVKIGRSIFEVy +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI001427ECEC +----EQPYSQLEARDTARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVITIADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRE +QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQRILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] Beta-lactamase class A/beta-lactamase class A CARB-5 n=1 Tax=Pseudomonas guariconensis TaxID=1288410 RepID=A0A1G6K5N6_9PSED +---IQEAAPQIERTLKATVGYSIHDTGTGRSW-QYRADERFPMASTVKLLLCSTLLNEG- +--QALMTRSVPIHSQDILAYAPVTKDLVGTHVPAAKLCAITLKTSDNTAANAVFEVLGGP +KVVTAFVRGLGDQTTRSDRNEPSLNEVMPGDERDTTTPRAMANTVKALLLGTALDTPSRA +QLTEWLSNNEVGGPLLRAAIPNDWQIADRTGSGSFGARGIAAVLWPPRGEAIVATIYLKD +TEASLDERNAAIAAIGRAMVK-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=A0A260U0X5_RHOFA +----EQPYSQLEARDTARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVITIADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRE +QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQRILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] Beta-lactamase n=1 Tax=Carnobacterium maltaromaticum TaxID=2751 RepID=A0A494QX91_CARML +-kAIDSDLKKLEKEYEATLGVYAIDTETNKTI-NYNGEQRFAFASTYKALAGGLVLDKFN +--WDELNQTMMINQEDLVDYSPITEKYVGIGMPLKDIIGAAMEYSDNTAGNILFDQLGGP +AGFQKELEKLGDHTTESVRYEPELNEAIPGDCRDTSTPKAIALDLKKLTADKTLAPDKLT +FYKKQLVENKTGGNLIRAGIPTDILVGDKSGAASYGTRNDIAVLYPPDRKPIVLVIFSNK +TNKDDAYQDELIAKSAKLVGDYf +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas TaxID=286 RepID=UPI0003A8DD53 +----QEAALQIERTLKATVGYSIHDTGTGRSW-QYRADERFPMASTVKLLLCSTLLNEG- +--QALMTRSVPIHSQDILAYAPVTKDLVGTHVPAAKLCAITLKTSDNTAANAVFEVLGGP +KVVTAFVRGLGDQTTRSDRNEPSLNEVMPGDERDTTTPRAMANTVKALLLGTALDTPSRA +QLTEWLSNNEVGGPLLRAAIPNDWRIADRTGSGSFGARGIAAVLWPPRGEAIVATIYLKD +TEASLDERNAAIAAIGRAMVK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5UWS2_9BACT +-----DRFTSIEARIGGHLGVAAIETASGKRI-DYRPDERFPMCSTFKFLAVAAVLKRVD +EKQERLDHFVPYGQREILEYAPVIKEHVKEGMILGALCEAAIEQSDNTAGNLLLDAIEGP +AGLTNFVRSLGDKMTRLDRKEPELNSAIPGDERDTTTPGSMLADMMRLLVGDVLSPSSRR +QLEDWLQKNKTGAAMIRAGAPTTWIIGDKTGRGANGATNDIAIMHP-------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium llatzerense TaxID=280871 RepID=A0A0D1JSY8_9MYCO +------RFEELEDRYQALIGVYAVDLESLATV-EHRADERFSICSTFKAYAAARILQMAK +AGQANLDAMVPITAADIVVNSPVLSPAVGTRMELREICAAALTQSDNAAGNIMLRTIGGP +SALTAFARSIGDSQTRLDRWEPDLNDAAPGDLRDTTTPRALCGGYRAILVGDALSGAGQF +QLKRWMTETTTSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGLLIGPKRERVMLTVLIRT +RTRDAGPFNEAVAESVRSV---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. ANT_H53B TaxID=2597357 RepID=UPI0011EDA1C8 +-----QVYLDFEARDNARLGVSAVDLASDSTE-SHRGDERFAFCSTFKVYAVGAVLAAVD +AGALQLSDTRTITAADKVPESAVD-WTPGSVVSIADLAAAALTESDNTSGNLLIREAGGT +AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTAASRE +QLLAWMADTQTSDARFRAALPAGWTSADKTGTGSYGVSNDAGLLLGPDGQRFLVVVLSAT +TSEDSPAMNSLVADATRQVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Sandarakinorhabdus sp. MO-4 TaxID=2672568 RepID=UPI0013DD82B1 +---LRRAIAGIERSAGGPIGVALIDTGNGARF-SHRADQRFPLCSTFKLLLAARLLDGAR +RGQWRMDERLPVRREDMLFNAPFTEKRIGGSASLTEMAEAMVVQSDNPAANLALARVGGP +AALTIWLREIGDTVTRLDRNEPEMNNEVPGDPRDTTTPSAMLATCRRLVAGPLLPAPARA +QLLGWMAASRTADTMFRAALPPGWREANKTGAGSWHARNIVSIITPPGRQPIWVAAYLFA +AKAELEERNRQFVPLGRAIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0007C5C7B0 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDIKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 05-2254-6 TaxID=2022489 RepID=UPI000B9B02FA +-----QVYLDFEARDTARLGVSAVDLASDSTE-SHRGDERFAFCSTFKVYAVGAVLAAVD +AGELQLSDTRTITAADKVPESAVD-WEPGSVVTIADLAAAALTESDNTSGNLLIREAGGT +AALTEFARSLGDTEFRLDRTEPELNTAIHGDPRDTTTPNSMAAGYRTLLDGDVLTEASRD +QLLAWMADTQTSDARFRAGIPDGWTSADKTGTGSYGVSNDAGLLLGPDGQRILVVVLSAT +TSEDSPAMNSLVADATRQVVEQ- +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. Leaf20 TaxID=1735685 RepID=A0A0Q4G9A0_9SPHN +-------IAAYEAATGGHVGVYARNVATGRTI-AWRPDERMVMCSTFKASLAACVLARVD +RGRARLADPLRLDAADMQDHAPVARANLARGMSVGEMCRAVVEQSDNSCANILLREIGGP +AGMTRFWRALGDDVTRLDDVEPVLNRTPPGGIRSTTTARSMATILETLTLGPVLSPGSRA +TLVAWLKGCRTGDNRLRAGLPDGWAVGDKTGNNGRDAAGDIALVWPRPGVPIVVSVYTRG +GSPVEAQFAALFAGIGRAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces luteoverticillatus TaxID=66425 RepID=A0A3Q9FZH9_STRLT +--EITRRLGQWEREHSVRIGVYARDTATGRTV-EYGADDAFPMCSVFKTLAAAAVLRQDR +-HGELLGKRIHYTEQFLKDYADSTKNNLANGMTVAELCAAAVSESDNAAANLLLRELGGP +TAITRFCRSLGDDTTRLDRWEPQLNSAEPDRETDITTPGAIGRTYERLVLGHALTGPDRE +RLTGWLIANTTNKQRFGKGLP-GWTLADKTGGGDYGVANDVGVVWPPHRRPIVLAVLTTA +LSATAPTNNALVADIAALV---- +>[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0009EB279B +---FQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD +RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP +QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ +QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIA----- +----------------------- +>[subseq from] BlaVCC-1 n=2 Tax=Vibrio cholerae TaxID=666 RepID=A0A0U3IB62_VIBCL +--EHNKNMADIEAAFEGRVGVYAINTGSGKAY-SYRANERFPLCSSFKAFLAAAVLKMDQ +DSPGVLLEKVNYHNRTMEPHSPITEKFQSQGMAVGELAAATLQYSDNGAANLLMEKIKGP +EGMTQFMNSIGDTKFRLDRWELDLNSAIPGDERDTSTPKAVAESLNKLISNTVLDNYHQE +IFKKWMIGNTTGDNRIRAAVPDGWVVGDKTGTCGYGTANDHAFILQGNNAPLILSIYTTR +KGEHMKHDDEVIAKAARIAIE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudomonas guariconensis TaxID=1288410 RepID=A0A2N5QE25_9PSED +----QEAALQIERTLKATVGYSIHDTGTGRSW-QYRADERFPMASTVKLLLCSTLLNEG- +--QALMTRSVPIHSQDILAYAPVTKDLVGTHVPAAKLCAITLKTSDNTAANAVFEVLGGP +KVVTAFVRGLGDQTTRSDRNEPSLNEVMPGDERDTTTPRAMANTVKALLLGTALDTPSRA +QLTEWLSNNEVGGPLLRAAIPNDWQIADRTGSGSFGARGIAAVLWPPRGEAIVATIYLKD +TEASLDERNAAIAAIGRAMVK-- +>[subseq from] RCP family class A beta-lactamase n=1 Tax=Gemmobacter sp. HB-1 TaxID=2652247 RepID=UPI00124F0C76 +-eALSETVARIEEQLGARVGLSLMETGTGWSW-SHREDELFLMNSTVKVPVCGAILARWD +AGRLSLSDALPVRKADLVPYAPVTETRVGGNMTLDELCLAAIDMSDNVAANILIGHLGGP +EAVTQFFRSVGDPTSRLDRIEPKLNDFASGDERDTTSPAAMSETLRALLLGDVLSPEARG +KLAEWMRHGGVTGALLRAEVEDAWLILDKSGSGSH-TRNLVAVIQPEGGAPWIATMFISD +TDAEFEVRNEALKDLGRAVV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A649UHH7_ACIBA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGW------------------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Gluconobacter japonicus TaxID=376620 RepID=UPI000782EA90 +--------SSYEEATGGHIGVFARNLATGQRL-TWRENERFVMCSTFKASLAALTLLRVD +QGKESLETVVPYTASDLGDYAPVAKANVAAGLSVRAMCQAAVEWSDNVCANLLLARVGGP +AALTRFWRSLGDRQTRLDDWEPVLNRTPQGGLRNTTTPEAMAWILEHLVFGHALSGASCS +LLTGWMKNCQTGKGRLRAGFPPTWDVGDKTGNNGKDAAGDIAVAWPTREAPLIVCAYTRG +GQPDEKQFFEVFSEIGRIAAE-- +>[subseq from] Beta-lactamase n=3 Tax=Carnobacterium maltaromaticum TaxID=2751 RepID=K8ENU7_CARML +-kAIDSDLKKLEKEYEATLGVYAIDTETNKTI-NYNGEQRFAFASTYKALAGGLVLDKFN +--WDELNQTMMINQEDLVDYSPITEKYVGIGMPLKDIIGAAMEYSDNTAGNILFDQLGGP +AGFQKELEKLGDHTTESVRYEPELNEAIPGDCRDTSTPKAIALDLKKLTADKTLAPDKLT +FYKKQLVENKTGGNLIRAGIPTDILVGDKSGAASYGTRNDIAVLYPPDRKPIVLVIFSNK +TNKDDAYQDELIAKSAKLVGDYf +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudomonas sp. HMSC08G10 TaxID=1581141 RepID=A0A1F1Q9W4_9PSED +----QAAALQIERTLKATVGYSIHDTGTGRSW-QYRADERFPMASTVKLLLCSTLLNEG- +--QALMTRSVPIHSQDILAYAPVTKDLVGTHVPAAKLCAITLKTSDNTAANAVFEVLGGP +KVVTAFVRGLGDQTTRSDRNEPSLNEVMPGDERDTTTPRAMANTVKALLLGTALDTPSRA +QLTEWLSNNEVGGPLLRAAIPNDWRIADRTGSGSFGARGIAAVLWPPRGEAIVATIYLKE +TEASLDERNAAIAAIGRAMVK-- +>[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. S-62 TaxID=2653123 RepID=A0A5J4M6K7_9RHIZ +----------IETKSGGELGVAVLDTGTNQVV-GHRLDERFALCSTFKVLAIAFVLARVD +QGKEQLDRRVDFSEQDLVLPYKATKPHVGAEMTIDELCKAAAIYSDSTAANLLLASFGGP +AELTDYLRSIGDNVTRVDNVEPKLNIVKPGELHDTTSPRAMAETMKRIILGDMLSPRSRG +LLTDWLVNGQDATQRLRKGVPAGWRIANKPGTWKGISTNDVGVIWPPHRPPVVVAAYLSH +APGSIESQEAVLADVARRVCD-- +>[subseq from] Beta-lactamase n=1 Tax=Roseibium hamelinense TaxID=150831 RepID=A0A562TAZ0_9RHOB +--ALENKLNELEQREDARIGLALIDTQTGTEF-SFRGTERFALNSTFKAFACGALLSQAE +AGGPNLSESRSIREDDLVSWSPVTKNRVGTDITLRESCEATMVYSDNTAANIVLQALGGP +AAFTAFMRDIGDRSTRLDRMEPDLNVVPAGTDQDTTTPEAAANSLKELITGELLAAPSKA +QLIAWLSANTTAKHMLRPHLPEGWTIGDRSGASRDRKRSVIAVIYPPDQAPVFVAVYLHL +EKAGIAERDAIIAELGKSIFD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. CB01881 TaxID=2078691 RepID=A0A652NT58_9ACTN +--AVARELAALEREHAARLGVFARNTATGATV-LYRADERFPLCSVFKPLAAAAVLRDVD +RNGGSLAKRIHYTAQEVKDYGPVTEENLANGMTIEALCAAAIGESDNLAGNLLLRELGGP +TAVTRFCRSTGDGRTRLDRWEPDLNSAEPWRTTDSTSPRAIGSTFGRLLLGDVLAPRDRE +RLTGWLLANTTNTERFRKGLPKDWTLADKTGTASYGVANDVGVVRPPDGPPIVLAVLTTT +HAATGPSDSALVARTAELL---- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012D9CC6B +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIIPWSPITEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAIGNTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEIGNAIFKEf +>[subseq from] Beta-lactamase n=1 Tax=Sphingorhabdus wooponensis TaxID=940136 RepID=A0A3R8R3J6_9SPHN +---ANAALAALEARAGGRLGALVLDTASGRMT-GHHYDDAFAMCSTFKLALAAAVLQQAD +QGRLKLDTVLPYSQADMVPHAPVTGPNLAKGMRIIDLAEAAQKTSDNVAANLLMKHLGGP +AAITAIFRSWGDDVTRLDRYEPDVNNVPPGEVRDTTTPRAFAWMMARLLTDDILQPSSRD +LLTQWMVDTATGMKRIRGGLPASWKSGDKTGTANNNKTNDVAIFWPPARPPVIVTAFYEA +DGQTRDSDQAVLAEIGKIAAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Falsirhodobacter deserti TaxID=1365611 RepID=UPI000FE3FA1F +-----ATITRWETQLSARIGVALHDSGSGQSW-GYREDERFPLNSTVKVPICGGILALAD +QDQLELEEGVTITEGDILSYAPVTREHVGEQLTVSDLCFAALDRSDNTAANLLIRRAGGV +GALTEFLRGIGDDVTRLDRMEPELNSYDTGELRDTTTPAAMIATLQRLAQGDALQPASQE +RLVGWMQPGGVTGPLLRPSIPEGWDIADKSGAGDN-SRSIVAMITPPGGAPAFLAIYIAQ +TDADLNTRNAAVAEIGAELV--- +>[subseq from] Beta-lactamase n=1 Tax=Microbacterium sp. L-033 TaxID=2614798 RepID=A0A5N0TIZ7_9MICO +--AVSDDIAGLEAQYQARVGVSALDTASGDSV-QYRADERFGFASTIKVFAAAAMLRQIP +--EDQRDARLTWTPEEMVAYSPVAEEHLGTGMTIREAAEAAVRRSDNTAMNLVLGRIGGP +AGLDAELVQLGDTTTEAIDSEPELNRVDPGSPANTTTPAAFTAALHEVMRSDYLAPTDRA +VLIEWMSGNATGDALIRAGAPAGWEVADKSGGAG-GMRNDIAIVTPPGRAPVILTVMTAK +DDPAAAYEDELVAAVARTVLSAf +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI000A3BDA9C +---ADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAHALGDPLDADERA +LFTGWLKATHTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRADAAPIVIAVHSAK +DQQDADADDALISGAAKAAAQ-- +>[subseq from] class A beta-lactamase n=2 Tax=Nocardiaceae TaxID=85025 RepID=UPI000B9B8729 +----EQPYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLTQASRQ +QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLMLGPEGQRILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] Beta-lactamase n=1 Tax=Carnobacterium maltaromaticum TaxID=2751 RepID=A0A0R2J8S9_CARML +-kTIDSDLKKLEKEYEATLGVYAIDTETNKTI-NYNGEQRFAFASTYKALAGGLVLDKFN +--WDELNQTMMINQEDLVDYSPITEKYVGIGMPLKDIIGAAMEYSDNTAGNILFDQLGGP +AGFQKELEKLGDHTTESVRYEPELNEAIPGDCRDTSTPKAIALDLKKLTADKTLAPDKLT +FYKKQLVENKTGGNLIRAGIPTDILVGDKSGAASYGTRNDIAVLYPPDRKPIVLVIFSNK +TNKDDAYQDELIAKSAKLVGDYf +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI0013276CEF +--AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARSA +LDASLLSRRTLYRRYDLVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QSVTAFAHDSGDTSFRLDRWEPALNAATPGDERDTSTPLAMAEALRRLLLGDVLREPERT +QLTKWMLGNTRGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ +PDAGAAPHADVVAAAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia bryophila TaxID=420952 RepID=A0A329BY07_9BURK +---TESPIAEIERRYGGRLGVFAINPASGRTL-AYRADERFLMCSTFKGLLVAQVLARVD +AGKENLERLVRYTERDLVFTSPVTKANVAQGMSVGALCQAAVEVSDNTAAILLMRSTGGP +AALTRFMRDIGDSVTRSDRYEPESNQA--SGVLDTTTPRAIATSAARILLGDVLNPESRR +QLDAWMVACKPGLNRIRASLPADWLAGDRPGTSVERETNDYAIVRPPGRAPLLVAVYYDA +PGVSMELRETVLREAGHR----- +>[subseq from] Beta-lactamase n=1 Tax=Kutzneria buriramensis TaxID=1045776 RepID=A0A3E0GZ79_9PSEU +-----PDLAALERKFGGRLGFYALDTASGKTV-AYRSGERFLMCSTHKVLVVGAILQLRQ +QQPGLLDRVITYDKSQVLSYAPITSQHS--GMKVAELCDAALRLSDNTADNLLIDLLQAP +QAVTAFARDLGDNVTHLDRKEPDLNDGAPGDERDTTRPPVFASDLNELTLGEGLDSAGRD +MLVNWMKSSTTGLDLVRGGLPPGWVAADKSGSGAKGEVNDVAVVWPPNRAPLVIAAYTAP +TDPKSTAGRKTIADATAIAVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia suismassiliense TaxID=2077092 RepID=UPI000D1E6CC3 +---ATARVSELESAHHARVGVFAVDTKTGVFL-GYRENERFPIGSTFKTLAVAALLREHP +LADGYFDTVIHFTADDLVKYSPVTETRVDTGMTVRELAAAAIEKSDNTATNELLKLLGGP +TSITKFVRTLGDTATSLDDWEPLSNSGDTNPEHNSTTPAALAADYRALISGDALPAPERA +QLTEWLLRSTTGLNRIRAGLPQDWKTGDKTGGGDYGLTNDAAVTWPPNSSPIVITVLSIN +TEEHAPADDPLVAQSAKAVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia autotrophica TaxID=2074 RepID=UPI0005623D00 +---AQAELADLERRAGGRLGVSALDTGSGAAL-GHRADERFLLCSTGKLLAAAAILHRFE +ADRDILERVVPYTSSVLVPNSPETGKH--TSMTVGELCHAAMTLSDNTAMNLLLGVLGGP +EKVTAFLRSAGDPVSRLDRTETALNAR--DGDLDTSTPARMAANTRLLALDDGLTPDNRD +VLVGWLKANTTGVTRIRAGLPADWVVGDKTGAGARGEINDVAVVWPPGRAPLVIAVYTEP +PDPD-ADAAPTVAEAARIVARSf +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. EPR-147 TaxID=1813676 RepID=UPI0007BB9EF7 +-----QVYLDFEARDNARLGVSAVDLASDSTE-SHRGDERFAFCSTFKVYAFGAVLAAVD +AGALQLSDTRTITAADKVPESAVD-WEPGSVVTIADLASAALTESDNTSGNLLIREAGGT +AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTAASRE +QLLAWMADTQTSDARFRAGIPDGWTSADKTGTGSYGVSNDAGLLLGPDGQRILVVVLSAT +TSEDSPAMNSLVSDATRQVVD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus sp. 2G TaxID=1570939 RepID=A0A1J0TK32_9NOCA +---VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA +EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP +GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGSGLPAPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] Beta-lactamase n=1 Tax=Celeribacter neptunius TaxID=588602 RepID=A0A1I3K968_9RHOB +--------REIEQALAARVGVFARNIDTGAEF-SHRAGERFAMCSTFKASLAALCLQRAD +RGELDLDERLSLNGVPLLPTSPVTSQQPPSGLEIRTLCKAIVERSDNTAANLLLDRVGGP +AAVTGFFRDIGDDVSRLDRTEMALNANTPNDPRDTTTPEAMARTVERLTLGTVLSEGARQ +QLVAWMRNEQNAKDRIRAAVPGSWTVANKPGTTPNGAANDIAALWSPDGPRFVLAVYIDT +RLDSVRPSVAAIREVAQIALR-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=D3J1E5_KLEPN +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPXMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIA--------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=UPI0002F4DCE9 +--AAQSQLDALEKASNGRLGVAALDTASGARI-AYRSRERFPVCATYAVVAVAAMLARSA +LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QAVTAFAHGSGDTSFRLDRWEPALNTAVPGDERDTSTPLAMAESLRRLLLGDVLREPERT +QLTRWMLGNTSGFAGIRAGVPSDWRVAGVGGAGGYGTTTDVAVLWPASRAPLVMAVSFTQ +PDAGAAPHADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Comamonas sp. JUb58 TaxID=2485114 RepID=A0A4R7FUM0_9BURK +--ALHKALTLIEAQSGGRLGVYALDAETGGEA-GYRSDESFPMCSTFKTLLAAHVLYLGQ +TGALDLGQQVLVTSADMVPYAPVTEKYKDQPISLLELSEAIVVLSDNVAANLLLRASGGP +EALTAWLRTLGDKATRLDRIEPLLNTAEPGDPRDTTTPRAMQATLQALLLGDVLKGYGRA +MLQQWLSDSRTGDKRVRAGLPSEWRVGGKTGAGAHSTANDCLIAWPNAAEGLIITAYLTG +GERTTAQSDEVMAKVGAAIAQ-- +>[subseq from] Class A beta-lactamase GES-40 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A3G3C179_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Dialister succinatiphilus YIT 11850 TaxID=742743 RepID=H1CXJ7_9FIRM +------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTIKVFTAAELLRQKN +--TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV +ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK +LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR +TEKNAKSDDAMIAEAAKRIFD-- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=D3X610_ACIBA +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] GES family class A beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI0005B38428 +---FRTDLEKLEREKAAEIGVAIVDPQGQIVA-GHRIEQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGRDMIVEWSPAAERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTPTSTH +TIERWLIGNQTGDATLRAGFPKDWVIGEKTGTCANGGRNDIGFFKAQDRD-YAVAVYTTA +PKLSAEQRDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 1274756.6 TaxID=1834076 RepID=A0A1A3JCZ7_9MYCO +--SVDQRLDELEARDNATIGVFAADLASGRTL-TYRATDSFAMCSTFKVYAAAAMLQRVQ +RDELTLDQPLFVPPAAIVPHSPRSAPNSGGSMTVAELCAAALQVSDNGAGNVLLQTLGGP +GAVTDFARSIGDGRSRLDRWETQLNAAVPGDPRDTSTPEALGNGYRALLTGDVLEPILRQ +QLDGWMRANET--SSMRAGLPPGWTSADKSGAGDYGSTNDVGIAYGPGGQRVLLALMTRS +RAPNADSQRALIGELTALI---- +>[subseq from] class A beta-lactamase n=1 Tax=Roseibium hamelinense TaxID=150831 RepID=UPI0012BBDE18 +--ALENKLNELEQREDARIGLALIDTQTGTEF-SFRGTERFALNSTFKAFACGALLSQAE +AGGPNLSESRSIREDDLVSWSPVTKNRVGTDITLRESCEATMVYSDNTAANIVLQALGGP +AAFTAFMRDIGDRSTRLDRMEPDLNVVPAGTDQDTTTPEAAANSLKELITGELLAAPSKA +QLIAWLSANTTAKHMLRPHLPEGWTIGDRSGASRDRKRSVIAVIYPPDQAPVFVAVYLHL +EKAGIAERDAIIAELGKSIFD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SET1_9BACT +-dDLAAKIVQLEQEKQARIGVAVTDQAGRTVL-GHRENERFALCSTFKLPLVAQVLWRID +QGREKSSRPLAYNVDALQEYAPVARRYAPSGMTVQEASLAALQWSDNTAANLLLDTLGGP +AGFTRFVRQNGDSTTRLDRPEPDLNSNQPDDPRDTTTPLAMSRLTSRLLWGNTLRPATRQ +QLQRWLIGNSTGDTTIRAGLPAGWLAGEKTGSCDLGGRNDAGFVRSPAGKNHALAIYTLA +PQLEPKERDALIAETARLVTA-- +>[subseq from] class A beta-lactamase n=1 Tax=Roseibium hamelinense TaxID=150831 RepID=UPI0011A39115 +--ALENKLNELEQREDARIGLALIDTQTGTEF-SFRGTERFALNSTFKAFACGALLSQAE +AGGPNLSESRSIREDDLVSWSPVTKNRVGTDITLRESCEATMVYSDNTAANIVLQALGGP +AAFTAFMRDIGDRSTRLDRMEPDLNVVPAGTDQDTTTPEAAANSLKELITGELLAAPSKA +QLIAWLSANTTAKHMLRPHLPEGWTIGDRSGASRDRKRSVIAVIYPPDQAPVFVAVYLHL +EKAGIAERDAIIAELGKSIFD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5R0S7_9BACT +------------------------------------------MCSTFKFLAAAAVLKRVD +EKQEKLERFVPYDAKEILEYAPVTKEHLKDGMTLGALCEAAIEQSDNTAGNLLLDAIGGP +AGLTNFARDLGDRITRLDRKEPDLNSAIPGDERDTTTPGSMLGEMTRLLTGDVLSQLSRR +QLEDWLQGNKTGAAMIRAGIPANWIISDKTGRGANGATNDIAIMHPPGRAPILLAIYSVG +STATADDRAAAIAEAAKIVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050CA72B +----EQPYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLTQASRQ +QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLMLGPEGQRILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] class A beta-lactamase n=1 Tax=Arthrobacter sp. Y81 TaxID=2058897 RepID=UPI000CE3616C +---LMRRVERLEREFSARVGLFVADGLTGAEF-GHRADERFAMCSTFKVYAAAAVLERAR +EGLTDLNRGIRIDPAGVVVNSPECADFAGSTLPLKWFCKVALTHSDNTAGNQLLEELGGP +AAIGAYARSLGDTETRLDRWEPELNNAERGDPRDTSTPRALAQGYRKLLLGDALSPETQT +RLTGWMLANVTSGTRIRAGLPGGWTSADKTGAGLFGTVNDVGIIRNPAGEPLVLAILTDS +ATADTPGSNELVAAVTRAVT--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0003606E05 +----DEAFARLEREYGAHLGLYAVDTGSGREV-TWNDTRRFSYNSTIKASLAAAVLHKNG +--IDGMDRVLHYDRSDLVANSPVSEKHVDSGMSLRALCDAAVRYSDNTAANVLFEDIGGP +GRLGEFLKSLHDKTTRTDRHETGLSEWSPGEKHDTSTPRQMASNLRGLVLGDTLPTAERR +QLTTWLRTNTTGATTIRAGLPKGWIVGDKTGTGYYAARDDIAVIWPPGRKPLVMAILTYR +DGKNAEANDKLLADAARAAVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Brachybacterium sp. CFH 10395 TaxID=2585206 RepID=UPI00126619B0 +-rDLRRALADLETAHDARIGVSARVVGDSPAL-THRGHERFALASTGKVLTSALVLREAT +--EERLQQIIRFTAADLEEYSPVTSEHVDEGMRLLELIDAALTRSDNTAQNLLFTELGGP +RAVQRRLRRLGDGVTRTDRTEPELNTAIPGDARDTTTPAQMATDLERATLGHALGRDRSA +QLLAMMRANTTGDAAIRAGVPSTWTVADKTGAGGYGTSNDIAVITRPHAAPLVLAVYTTG +RTEDAELPTDLIAQVTRHVVD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudonocardiaceae bacterium YIM PH 21723 TaxID=2340915 RepID=A0A419HFK3_9PSEU +-------LVELERGFGGRIGVSALDTGNGRTV-RYRSRERFMSCSTHKVLTVAAVLQARH +QQPGLLDRVIHYTQADCDAYAEITKRHVNEGMTVRELCDAAIRYSDNCADNLLFQLVDGP +AGVTRYVRGLGDRMTRLDRIEPELNKD-TGDDRDTTTPLQIGETLRWLTLGDKLDPVGRG +MLNDWMIRNTTGGDTIRKGLPVDWTVGDKTGTGTDNERNDIAVLWPPNRAPWIITVFTDP +DDPKSTKGNETIEKATAIVVKH- +>[subseq from] Class A beta-lactamase n=1 Tax=Cellvibrio sp. KY-GH-1 TaxID=2303332 RepID=A0A5J6PEL0_9GAMM +---VEKEIKFIEKNLSAHIGVAVLNTKTGGHW-HYKGNERVPLASTFKTIACAKLLHDAE +SDKALLGRTVLVKSDELVAYSPITEKYVGQEITLKDACAATMQTSDNTAANIIINAVAGT +QGITDFIRSIGDDVTRLDRFEPELNEALLNDIRDTTTPNAITKTINTLLFGPVLSKPSQL +QLKEWMINNQVTGNLLRSVLPEDWKIADRSGAGGFGTRSITAVVWGEAQPPLIISIYIAQ +TEASFSERNEALVRIGQSIFNSy +>[subseq from] class A beta-lactamase n=1 Tax=Diaphorobacter sp. HDW4B TaxID=2714925 RepID=UPI00140E1284 +--HFQQRLQALEARSGGRLGLSVQVLGGQTSL-GYREDEAFPMCSTFKLLLAARILHLSQ +LGEFPLEQALLYEKKDLVAYSPATEKHADAEMTIRALCEAAVVLSDNTAANLLLGLQGGP +AGLTRWLRTVGDMRTRLDRTETDLNTAIAGDPRDTTTPRAMGRAALALLTDKLLSPESQK +QLRDWLLASRTGDKRLRAGMPSDWKVGGKTGSGDNGTANEVSIVWSAQGAPMMVSAYLTG +AVVESDGRDAILAEVGKIAADWy +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium aichiense TaxID=1799 RepID=A0A378UMY4_9MYCO +------DLTPIEDRYSARVGMYALDLDTGGSL-EHRADTPFSMCSTFKTYAVARVLQLAE +LGRRDLAMTQQIAASDIVENSPVTSAHVGRSMRLDELCSAALINSDNAAGNLLLRCIGGP +PEITTFARSVGDDRSRLDRWETELNAAVPGDPRDTTTPRALSAGYREVLTGKVLNDGHRE +QMLGWMSRNATSEKRFRAGLPTGWTSADKTGAGSFGSTNDAGLLSGPNGQRIIMAVLTRS +RDPDAPPLNNAIAETVRLTLAAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=M4QHK6_9BACT +------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAISNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEGIKLQDHFCARPFRLAGFIADKSGAGERGSRGIIAALGPDGKPSRIV------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. SMB37 TaxID=2512213 RepID=UPI00104E1377 +--ALDERLAEIENRHAVRLGALAHSPGSGRTY-THRGDERFAMCSTFKVYAAAGILQLES +QGRLRLDDTVAVEPGDIVVNSPVTSENQGRLMTYEQLCEAALTRSDNTAGNLLLRRLGGP +DAVTTFARSVGDHATRLDRWEPELNDAARGDERDTTTAVGLARGYRDLLLGSALDPAHQR +ILTGWMRASTTSDTRMRAGLPSGWVAADKSGGGYFATLNAAGVVWSPEGEPLVLVILSDT +TTVDAPFENAPIVDTTAAL---- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C826A26 +-----QSIEQIESRVSARIGIAVYDSGTKQTW-SYKGDERFPMMSTFKTLACANLLYDFE +NEGLDLGLKVDIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE +TEFTIQERDKVINEIGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI0010BDF6E5 +-----QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE +NEGLDLGLKVDIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE +TEFTIQERDKVINEIGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio tasmaniensis TaxID=212663 RepID=UPI00031AD7EA +----SQSIEQIEYRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYEFE +NEGLDLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVETLNELVYGNMLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWNIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE +TEFTIQERDKVINEIGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Carnobacterium maltaromaticum TaxID=2751 RepID=UPI0012F8C5F3 +-kAIDSDLKKLEKEYEATLGVYAIDTETNKTI-NYNGEQRFAFASTYKALAGGLVLDKFN +--WDELNQTMMINQEDLVDYSPITEKYVGIGMPLKDIIGAAMEYSDNTAGNILFDQLGGP +AGFQKELEKLGDHTTESVRYEPELNEATPGDRRDTSTPKAIALDLKKLTLDKTLAPDKLT +FYKKQLVENKTGGNLIRAGIPTDVLVGDKSGAASYGTRNDISVLYPQNRKPIVLVIFSNK +TNKDDAYQDELIAKSAKLVSDYf +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium sp. CECT 8783 TaxID=2358193 RepID=UPI000F0B72FD +---VHDRIEALQRRHNAKIGVYTINLDSGRTV-SHLDGESFAMCSTFKGYAAARVLQMVQ +NGELTLDRQVFVDPEQTSLNSPRTAANSGGQMTLAELCAAAVQVSDNAAGNLLLQTIGGP +SAITDFARSIGDDRTRLDRWEIELNTAIPGDPRDTSSPRALGGGYRNLLTGDVLAAPQRQ +QLEDWLRANET--SSMRAGLPEGWTTADKTGNGDYGSTNDVGMAYGPRGQRLLLAIMTRS +QANDAANNRPLIGELTTL----- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. SMB37 TaxID=2512213 RepID=A0A4R2DEL9_9NOCA +--ALDERLAEIENRHAVRLGALAHSPGSGRTY-THRGDERFAMCSTFKVYAAAGILQLES +QGRLRLDDTVAVEPGDIVVNSPVTSENQGRLMTYEQLCEAALTRSDNTAGNLLLRRLGGP +DAVTTFARSVGDHATRLDRWEPELNDAARGDERDTTTAVGLARGYRDLLLGSALDPAHQR +ILTGWMRASTTSDTRMRAGLPSGWVAADKSGGGYFATLNAAGVVWSPEGEPLVLVILSDT +TTVDAPFENAPIVDTTAAL---- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T0R2_9BACT +------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTYKVFTAAELLRQKN +--TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV +ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK +LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR +TEKNAKSDDAMIAEAAKRIFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia fungorum TaxID=134537 RepID=UPI0005D8CF7F +-----VSLADVERRHGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLARVD +AGKEDPGRLVRYTEKDLVFTSPVTKAHVAEGMPVGALCQAIVEVSDNTAAVLLMRSAGGP +AGLTQFVRGLGDTVTRSDRYEPESNRY--SGVLDTTTPRSIANSASKILLGNVLSPQSRA +QLEKWMIACKPGLNRLRAALPADWVAADRPGTSVEEQTNDYAIVRPPGRAPLLIAAYYDA +PALGMPAREAVLREVGAVFV--- +>[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia TaxID=1822464 RepID=A0A2N8Q8M0_9BURK +-----VSLADVERRHGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLARVD +AGKEDPGRLVRYTEKDLVFTSPVTKAHVAEGMPVGALCQAIVEVSDNTAAVLLMRSAGGP +AGLTQFVRGLGDTVTRSDRYEPESNRY--SGVLDTTTPRSIANSASKILLGNVLSPQSRA +QLEKWMIACKPGLNRLRAALPADWVAADRPGTSVEEQTNDYAIVRPPGRAPLLIAAYYDA +PALGMPAREAVLREVGAVFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. K24 TaxID=1472716 RepID=UPI0004AA9A82 +-----VSLADVERRHGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLARVD +AGKEDPGRLVRYTEKDLVFTSPVTKAHVAEGMPVGALCQAIVEVSDNTAAVLLMRSAGGP +AGLTQFVRGLGDTVTRSDRYEPESNRY--SGVLDTTTPRSIANSASKILLGNVLSPQSRA +QLEKWMLACKPGLNRLRAALPADWVAADRPGTSVEEQTNDYAIVRPPGRAPLLIAAYYDA +PALGMPAREAVLREVGAVFV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus biphenylivorans TaxID=1500843 RepID=A0A2Z4VQ14_9NOCA +---VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA +AGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP +GAVTAFARSVGDETTRLDRWEPDLNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050C467C +----EQPYSQLEARDAARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTLADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTSIPDDPRDTTTPNSMAAGYRTLLDGDVLTQASRQ +QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQRILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=I3VLI2_9BACT +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVLERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium sp. P9-64 TaxID=2024612 RepID=A0A5A7WQ70_9MYCO +---VEQLIAGLEQAHNAVIGVYAVNLISGVTI-AHRARDPFAMCSTFKTYAVARVLEMVG +RGQLTLDQPVLVDPAAVVANSPRTGPRAGTEMTLSELCQAALQVSDNTAGNLLLHTIGGP +PAITAFARSIGDQQTRLDRWETDLNSAIPGDLRDTSTPEALGSGYRALLSTEAPGPSTRQ +TLLDWMRANET--SSMRAGLPPGWTTADKTGSGGYGTANDVGIAYGPDGQHVLLAMMTRS +QADDAATLRPVIGELTSL----- +>[subseq from] class A beta-lactamase n=1 Tax=Marisediminicola sp. SM7 A14 TaxID=2711233 RepID=UPI0013ED7C95 +-----AEFDELEARYDATLGVFAVDTGTGVEV-EWRADDRFAYASTIKALAAAAALGRFG +--IDGMQQPVAIASSDLVSYSPVTETRVGGSMTLAEIADAAVTLSDNTAGNYLFEALGGP +GELDRALAVLGDDTTTVSRIEPQLNEAAPGDERDTSTPRAMAGSLREYVLGDALPEAERA +QLTEWLVASQTGGSLVGADLPGDWTIGDKSGAGGFGTRNDIAVVWPSTGEAIVIAVMSTR +GVEGAEYDDRLVAEAAAIAV--- +>[subseq from] Class A beta-lactamase GES-32 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A1B3B597_PSEAI +---FRTDLEKLEREKAAEIGVAIVDPQGQIVA-GHRIEQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGRDMIVKWSPAAERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTPTSTH +TIERWLIGNQTGDATLRAGFPKDWVIGEKTGTCANGGRNDIGFFKAQDRD-YAVAVYTTA +PKLSAEQRDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=2 Tax=Shewanella sp. SNU WT4 TaxID=2590015 RepID=A0A4Y6I9Z8_9GAMM +--NLQTQIEYWQTKLQVKIGVAVLNTANGQYW-GFQDEQRFPMASTMKMLACAKLLYDAD +NNRLQLSDKVTIEAADIITYSPMTEPLIGQAISVNDACQMTLTSSDNTAANIVLDAIGGP +VALTQFLRAQGDAITRLDRCEPELNQGMPEDVRDTTSPKAVVHTWQQLLTAKVLSESAKA +QLTTWLQHNQVANDLLRKTLPQGWLIADRSGAGGYGARGIVAMVWQPEQAPVFISIYLHQ +TTASMEQRNQAIAAIGDAIF--- +>[subseq from] Beta-lactamase n=3 Tax=environmental samples TaxID=48479 RepID=X2KVC5_9BACT +------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTHKVFTVAELLRQKN +--TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV +ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK +LLIDWMSDNSITDTLIKAGTPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR +TEKNAKSDDAMIAEAAKRIFD-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus pyridinivorans SB3094 TaxID=1435356 RepID=V9XHD3_9NOCA +---VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA +EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP +GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus pyridinivorans TaxID=103816 RepID=UPI0007CD6926 +---VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA +EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP +GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. RS1C4 TaxID=2022522 RepID=UPI000B9C684E +---AEKQFAALEQRFDARLGVFAVDLGSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD +AGTLSLTDTRIVEAEDKVPESAIDW-EAGQVVTLEQLCVAALTRSDNTAGNLLIDAVGGT +GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTDGPLSNSSRA +TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLGPDGRRILVVVLSRT +ANPDAAAMNELVADAVREVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Arthrobacter castelli TaxID=271431 RepID=UPI0009D6F561 +--SVKASFAELEEQYQGRVGVYAVDTETGHEV-QYRADERFAYASTHKVFSVAAVLAQSE +--PADLDEVVHYSSEDLVEYSPVTEKHVDSGMTVRSIMRAAIINSDNTAGNLLFDMLGGP +EGLQAYLAKLGDRTTSVDRIEPELNKWKPGQRRDTTTPRQAVTNLAALTHGNALEPWAQK +VLLEAMRDAENSDGLIRAAVPASTTVGNKSGAGGYGTRNDIAVIEREGQAPVFVAVYTNL +EDSDGVFDDAFVADAARAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C823892 +----SQSIEQIEYRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYEFE +NEGLDLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVDTLNELVYGNMLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE +TELTIQERDTVINEIGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI0005171845 +---VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD +RGEEKLDRRIFFGEKDLVAPFKATKPHIADGMTVEQLCEAAAIVSDSTAANLLMASFGGP +SALTTYLRSIGDQTTRVDKTELALNIVKPGEKHDTTSPRAMVGTLQRVVLGSALSPTSRA +LMTDWMMASRDAAQRLRAGLPAGWRIANKPGTWEGISTNDIGVLFPPNRPPIIVAAYLGK +ARGSVTDQEAVLAEVARIIT--- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI0003BEDA63 +---VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD +RGEEKLDRRIFFGEKDLVAPFKATKPHIADGMTVEQLCEAAAIVSDSTAANLLMASFGGP +SALTTYLRSIGDQTTRVDKTELALNIVKPGEKHDTTSPRAMVGTLQRVVLGSALSPTSRA +LMTDWMMASRDAAQRLRAGLPAGWRIANKPGTWEGISTNDIGVLFPPNRPPIIVAAYLGK +ARGSVTDQEAVLAEVARIIT--- +>[subseq from] Class A beta-lactamase GES-35 n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A2U8YKA8_ACIBA +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPELGDNTPGDLRDTTTPIAMARTVAKILYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus pyridinivorans TaxID=103816 RepID=A0A495NF03_9NOCA +---VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA +EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP +GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI00083782D8 +--------DRIRGETGARLGVAVYDSGTGRRF-SDGAEARFAMCSTFKVPLVAAVLARVD +RGELDLAREIRFGEADVLDYAPVVKANLAKGLSIDALCEAAVVMSDNSAANLLFGQISGP +RGLTKFIRDAGDQLTRSDRDEPSLNNVRNGEVRDTTTPEAMLWLMNRLLLGDVLTPASRA +KLIGWMEASPTGKDRLRAGLPKDWRVGDKTGTSGEGYFNTIAIATPPGRKPILITCYLDA +PGLNSAKANAAHAKVGELVG--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudescherichia vulneris NBRC 102420 TaxID=1115515 RepID=A0A090VWE0_PSEVU +---LQAFLEQEETRLPGKIGMSIVNADGQPIF-GYRQNERFPLTSTFKVLACAALLDRLH +KTAGLLDQTVTIKPDELLSYSPITKNYVAPAITLQTLCSAAVSYSDNTAGNSILTYLGGP +AAVTRFMRESGDTVTRLDRTEPTLNEATPGDERDTSTPERMASGLHTLLATPLLTKPHQA +MLESWMREDKVADNLLRAALPKGWFIADKTGAGGYGSRAIIAAVYPTGEKPVYMAIYITQ +TDAEMKVSDGVIQKIGER----- +>[subseq from] class A beta-lactamase n=1 Tax=Gluconobacter japonicus TaxID=376620 RepID=UPI0007826EF0 +--------SSYEEATGGHIGVFARNLATGQRL-TWRENERFVMCSTFKASLAALTLLRVD +QGKESLETVVPYTASDLGDYAPVAKANVAAGLSVRAMCQAAVEWSDNVCANLLLARVGGP +AALTRFWRSLGDRQTRLDDWEPVLNRTPQGGLRNTTTPEAMAWILEHLVFGHALSGASCS +LLTGWMKNCQTGKGRLRAGFPPTWDVGDKTGNNGKDAAGDIAVAWPTREAPLIVCAYTRG +GQPNEKQFFEVFSEIGRIAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI0011D11E1E +--------QRVETELGMRVGFAVLDMGSGEVR-RYRAIERFAMASTFKALACAAALSA-- +-GPSVLDKQTRISKADLRPHSPVTEKRVGTSLSTRALCEITLRTSDNAAANAVLAAIGGP +PAVTTFLRGIGDDTTRLDRYEPELNEATPGDPRDTTTPQAMAETVRRLLLDHALEPKARD +QLEAWMAANAVAGALLRAELPKGWAIADRSGAGGHGTRGVIALLRPPEDAPLVVAIYMDG +RKHPLKVRDAAIAEIGAAIFAEy +>[subseq from] Beta-lactamase n=1 Tax=Nocardia sp. CS682 TaxID=1047172 RepID=A0A4P7GYD3_9NOCA +--RATAQVRDLESAHHARVGAFAVDTKTGVFL-GYRENERFPIGSTFKTLAVAALLREHP +LADGYFDTVINFTADDLVKYSPVTETRVGTGMTVRELAAAAIEKSDNTATNELLKLLGGP +TAITKFVRTLGDTATSLDDWEPLSNSGDTNPEHNSTTPAALAADYRALVSGDALPAPERE +QLIEWLLRSTTGLNRIRAGLPQDWKTGDKTGGGDYGLTNDAAVTWPPNSAPIVITVLSIN +TEENAPADDPLVAQSAKAITE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. SRS-46 TaxID=2094191 RepID=A0A4R4CDL8_9BURK +--AAHSQLDALEKASNGRLGIVALDTASGARI-AHRSRERFPMCATYAPVAVAAMLARSA +LDPSLLPRRTLYRRYELVPGSPVTESRADTGMTIGQLCEAVLQSDDKSAANLLMRVLGGP +RVVTAFAHDSGDTSFRLDRWEPALNTAAPGDERDTSTPLAMAESLRRLLLGDVLREPERT +QLTKWMLGNTSGFAGIRAGVPSDWRVASRGGAGGYGTTTDVAVLWPTSHAPLAMAVSFTQ +PDADAAPHADVVAQAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Listeria newyorkensis TaxID=1497681 RepID=UPI00051DD231 +-eEAKAELKKLEEKYGATLGIYAVNTADKKKI-SYNDQERFAYVSTYKAIAGGLLLKNLT +--TEQLNKRIYFSKEDLVDYSPVTEKHVDSGMTVKEIINAAMTYSDNTAGNILFQQLDDP +KGYQKELAKIGDKTTQADRLEPELNEAVPGDKRDTTTPEAMANVLSFLTTKGNMASDRLD +YFKQTLIDNTTGDKLIRAGVPAGYTVGDKTGAGSYGTRNDIAVIYPKDKKPLVWVIYSKK +SGKDDEYNDQLIADAAKVLSNYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia catarinensis TaxID=1108140 RepID=A0A1J9NQP4_9BURK +--AAQAELAALETASNGRLGVAALDTSNGVRI-AHHAASAFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCEAMLQSGDKGAGNLLMGVLGGP +QAVTSFAHESGDTTFRLDRWEPELNKVAPGDERDTSTPVAMVDTLQRLLLGDTLQEPQRA +QLTEWMAGGARGATGIAAGVPPGWRIAGNAGTGGYGTTTDIAVLWPPSRAPLVTAVSFTQ +PQADAAARADVVALAARIAA--- +>[subseq from] Beta-lactamase n=2 Tax=Mycobacterium TaxID=1763 RepID=A0A1S1NGH5_9MYCO +-------VEDLERRRHATIGVFAVNLSSGRSV-AHRAGEPFAMCSTFKVYAVARILQLAH +HGELRLDHAVRVDPTAIVANSPRTQPRAGGDMTIDELCRAALQRSDNTAANLLLTIIGGP +PAVTAFARSIGDQRSRLDRWETDLNAALPGDPRDTSTPEALGGGYRALLVGDALAPEHRQ +LLNNWMRANET--SSMRAGLPPGWTTADKTGSGDYGSTNDIGIAFGPEGQRVLLAMMMRS +QTDDPN----------------- +>[subseq from] Beta-lactamase n=1 Tax=Actinoplanes sp. N902-109 TaxID=649831 RepID=R4LF89_9ACTN +--------------------MYALDVKSGHAV-AYRADERFAYASTYKALAAGALLAHTS +--DADLDDMVTYQRADLVAHSPVTGKKLADGISIGDAAEAAVRVSDNTAANLVLRELGGP +AGWEKDLRGVGDTVTEAARTEPELNAATPGDKRDTSTPRALAADLRAYVLDDALDAGDRS +TLTRWMTGNATGNTLIRAGVPKGWTVADKSGGGQYGTRNDIAVVWPEPDRPLVLAVLSSR +AGADADYDDALIARAASVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Selenomonas sp. mPRGC8 TaxID=2606905 RepID=A0A5D6WED5_9FIRM +------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTHKVFTAAELLRQKN +--TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV +ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKQ +LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR +TEKNAKSDDAMIAEAAKRIFD-- +>[subseq from] Beta-lactamase n=1 Tax=Pusillimonas sp. (strain T7-7) TaxID=1007105 RepID=F4GRQ5_PUSST +------LLAALERNHGGRLGVAILDTATGMRS-AYRGDERFLICSTFKLLLVAAVLKRVD +NNKERLGRRISFDKSEILAWAPVTSLNVGSPMSIQELCEATMIMSDNTAANLLLKTLGGP +AAITTYARGLGDTKTRLDHIEP-LNGNQQG-DEDTTTPWSMLQNMQKILLGNALSEESKT +RLVNWFSMNQTGSQALKAGLPPDWLIGDKTGAASN-ANNDIALITPPGRQPILVTAYYIN +DTKNSRARKEVLAKVGS------ +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI001303DF66 +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAMPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDSTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVITVHSAK +DQQDADADDALISGAAKAAAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Aliivibrio sifiae TaxID=566293 RepID=A0A2S7XJ09_9GAMM +--SLTENIEAIELSSSGTIGISVLDTATNTTW-NYKGDQRFPMMSTFKTLLCAQMLYNSS +DGILDKQAQTRITQEALIPWSPITEKQIGETITTEKACEATMLMSDNTAANIVLAEIGTP +SSLTLFLRFIGDNTTRLDRIEPALNEAKSGDIRDTTTPNAMTNTLNELLFGQTLNAKDKR +TLKAWMVNNKVSDPLLRSILPQQWFIADRSGAGGFGSRGITAIVWSEQRSPIIIAIYLKQ +TDLNIAERNQVIVEVGNAIFKEf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ADI91-18 TaxID=1522755 RepID=UPI000F553EE8 +---LAGALGELEREHSARLGVFARNTATGRTV-AYRADERFPMCSVFKTLAAAAVLRDLD +RDGEFLARRIRYTAEEAEKYAVVTGRNVANGMTVEALCTAAVSESDNMAANLLLRELGGP +RAITRFSRSLGDRITGLERWEPELNSAEPWRTTDTTSPRAIGTSYGRLLLGDALDPRDRE +RLTGWLLANTTNGERFRAGLGPDWILADKTGGGNYGVTNDVGVVRAPDGPPIVMSVLSTK +PGPEGPRDNPLVAKTAALLAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio wodanis TaxID=80852 RepID=UPI00076A6F55 +--SLTENIEAIELSSSGTIGISVLDTATNTTW-NYKGDQRFPMMSTFKTLLCAQMLYNSS +DGILDKQAQTRITQEALIPWSPITEKQIGETITTEKACEATMLMSDNTAANIVLAEIGTP +SSLTLFLRFIGDNTTRLDRIEPALNEAKSGDIRDTTTPNAMTNTLNELLFGQTLNAKDKR +TLKAWMVNNKVSDPLLRSILPQQWFIADRSGAGGFGSRGITAIVWSEQRSPIIIAIYLKQ +TDLNIAERNQVIVEVGNAIFKEf +>[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas iranensis TaxID=76862 RepID=UPI0013D02FCD +--DVAAALADVEARHGVRLGVHALDTVTGATA-SHRADERFAFCSTVKPLAAAAVLAAR- +-GVAGVDERVPVEADDLVTYSPVAEQRVGVGMTWRELVDAALRFSDNTAGNLLLAGAGGP +AALTAWLRGLGDDVTRSDRTEPELNAYAPGDDRDTSTPRALAGTYRALVVGDVLGGPERD +LLTDAMLRSTTGDALVRAAARPGWEVADKSGAGAYATRNDVAVVWTPAGAPVVLAVLSDR +ADPAAERADAPVAQAARVVLD-- +>[subseq from] Beta-lactamase n=5 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A097ZLX5_ACIBA +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRTAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI0009A58B97 +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAHALGDPLDADERA +LFTGWLKATHTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRADAAPIVIAVHSAK +DQQDADADDALISGAAKAAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 14-1411-2a TaxID=2023151 RepID=UPI000B9B57A2 +-----QVYLDFEARDNARLGVSAVDLASDSTE-NHRGDERFAFCSTFKVYAVGAVLAAVD +AGTLQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLASAALTESDNTSGNLLIREAGGT +AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTTDSRE +QLLAWMADTQTSDARFGAGIPDGWTSADKTGTGSYGVSNDAGLLLGPGGQRILVVVLSAT +TSEDSPAMNALVADATRAAVE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus pyridinivorans AK37 TaxID=1114960 RepID=H0JPL8_9NOCA +---VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA +EGSLRLDETLPIDSEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP +GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. ADI95-16 TaxID=1522758 RepID=A0A3G4VPX0_9ACTN +-----GALGELEREHSARLGVFARNTATGRTV-AYRADERFPMCSVFKTLAAAAVLRDLD +RDGEFLARRIRYTAEEAEKYAVVTGRNVAGGMTVEALCAAAVSESDNMAANLLLRELGGP +RAITRFSRSLGDRITGLERWEPELNSAEPWRTNDTTSPRAIGTSYGHLLLGEALNPRDRE +RLTGWLLANTTNGERFRAGLGPDWILADKTGGGNYGVTNDVGVVRAPDGPPIVMAVLSTK +PGPEGPRDNPLVAKTAALLAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A5C0PBD5_PSEAI +-qQVEQDAKVIEASLSAHIGISVLDTQTGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE +QGEINPKSTIEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNAAANIILNALGGP +ESVTDFLRQIGDKETRLDRIESELNEGKLGDLRDTTTPNAIVNTLNELLFGSTLSQDGQK +KLEYWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEAQSPIIVSIYLAQ +TEASIADRNDAIVKIGRSIFEVy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Mg1 TaxID=465541 RepID=A0A0G3UI28_9ACTN +---LAGALGELEREHSARLGVFARNTATGRTV-AYRADERFPMCSVFKTLAAAAVLRDLD +RDGEFLARRIRYTAEEAEKYAVVTGRNVANGMTVEALCAAAVSESDNMAANLLLRELGGP +RAITRFSRSLGDRITGLERWEPELNSAEPWRTTDTTSPRAIGTSYGRLLLGDALDPRDRE +RLTGWLLANTTNGERFRAGLGPDWILADKTGGGNYGVTNDVGVVRAPDGPPIVMSVLSTK +PGPEGPRDNPLVAKTAALLAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB03578 TaxID=1718987 RepID=A0A1Q4Z3U9_9ACTN +---LAGALGELEREHSARLGVFARNTATGRTV-AYRADERFPMCSVFKTLAAAAVLRDLD +RDGEFLARRIRYTAEEAEKYAVVTGRNVANGMTVEALCAAAVSESDNMAANLLLRELGGP +RAITRFSRSLGDRITGLERWEPELNSAEPWRTTDTTSPRAIGTSYGRLLLGDALDPRDRE +RLTGWLLANTTNGERFRAGLGPDWILADKTGGGNYGVTNDVGVVRAPDGPPIVMSVLSTK +PGPEGPRDNPLVAKTAALLAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 1274761.0 TaxID=1834077 RepID=A0A1A3SP98_9MYCO +-----DRIETLQRRHNARIGVYAVDLASGRTM-SHLDGETFAMCSTFKGYAAARVLQMVA +DGELSLDRQVFVDPVQAALNSPRTAPNAGGQMSLADLCAAAVQVSDNAAGNLLLQTIGGP +TAITDFARSIGDNRSRLDRWETELNSATPGDPRDTSTPNALGGGYRRLLTGDVLAPPQRQ +QFEDWMSANET--SSMRAGLPSGWTTADKTGNGDYGSTNDVGMAFGPGGEKILVAIMTRS +QSNDAPNNRPMIGEVTAALV--- +>[subseq from] EsbL n=1 Tax=Escherichia coli TaxID=562 RepID=H6U587_ECOLX +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas turrisvirgatae TaxID=1888892 RepID=A0A1E3LUG6_9SPHN +-------LARLRDETGGRIGLAVFDTGTGRRY-FDGAEARFAMCSTFKLPLAAAVLEAAD +RGRVDLKRDIRFGEADLLDHAPVVKANLAKGLPIATLLEAAVVMSDNSAANLVFGQIGGP +RGLTKFFRDAGDSVSRSDRDEPELNNVRDGDLRDTTTPQAMLWLMNRILLGDVLSPASRA +KLIGWMEASPTGKDRLRAGLPKAWRVGDKTGTSGDGYFNDIAIATPPGRKPILIACYLDA +PGIDGAKANAAHAQMGALI---- +>[subseq from] Bla(GES-14) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=C5HUY1_ACIBA +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Extended-spectrum beta-lactamase GES-11 n=4 Tax=Pseudomonadales TaxID=72274 RepID=I3VFR3_ACIBA +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] GES family class A beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI0009A9A4C7 +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderiales bacterium PBB2 TaxID=2015564 RepID=A0A257FLG3_9BURK +----DAACRALEARLGGQIGVFALDTGSQARL-AYRADQRFAMCSTFKLLLAAAVLARID +AGQLRPDQRLRYGPRDLVPHAPVTGALLQGGLTVAALCEAILVHSDNPAANLLLPLVGGP +PGLTRFAREQGDVITRLDRIEPALNSNEPGDPRDSSTPEAFVGLLDRL-LGSVLSDELRQ +QLLVWMNASETGLRRLRAGAPQDWPAADKTGTGARGAVNDVAVFFPPQRAPILMAVFMSG +SSQPLAALEAAHAELATRA---- +>[subseq from] Beta-lactamase n=2 Tax=Acetobacter TaxID=434 RepID=A0A252EJX7_9PROT +-----TAISQYENETGGHVGFYAENTKTGATL-GWRTDERFVMCSTFKASLAACVLARVD +GGLDALERQISYTAADIGDYAPVAKANLAKGMTIRELCAGAVEQSDNTCANLLLTHIGGP +SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGPVLSASSRT +ILTDWLIRCRTGEHRLRAGLPSAWKIGDKTGNNGKDAAGDIAVIWPHPETSIVVCAYTRG +GHPTEQQLSSVFAGIGKLVA--- +>[subseq from] Beta-lactamase n=4 Tax=Bacteria TaxID=2 RepID=BLAC_RHOCA +-eALSETVARIEEQLGARVGLSLMETGTGWSW-SHREDELFLMNSTVKVPVCGAILARWD +AGRLSLSDALPVRKADLVPYAPVTETRVGGNMTLDELCLAAIDMSDNVAANILIGHLGGP +EAVTQFFRSVGDPTSRLDRIEPKLNDFASGDERDTTSPAAMSETLRALLLGDVLSPEARG +KLAEWMRHGGVTGALLRAEAEDAWLILDKSGSGSH-TRNLVAVIQPEGGAPWIATMFISD +TDAEFEVRNEALKDLGRAVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000F5AFE05 +--AAQSQLDALEKASNGRLGVAALDTASGARI-GYRSRERFPVCATYAVVAVAAMLARST +LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT +QLMTWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ +PDAGAAPHADVVAAAARIAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2L1J0Z6_ECOLX +------------------LGVALISTADNSQI-LYRADERFAMCSTRKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDI------------------- +----------------------- +>[subseq from] class A beta-lactamase n=2 Tax=Pseudonocardia TaxID=1847 RepID=UPI00091B3059 +------ALADVEREYARTIGVHVLDTGTGAAA-GHRDGDRFLMCSVVKALMAGFVLHRSL +SEPGLLDRPVRYGRADLLEYAPVTTRNLAAGMTVAQLCEAAVTVSDNTAHNLLLREVGSP +AELTAWLRTTGDTVTRSDRAETALNDR--DGERDTSTPAALAATLRTLVLGDALPPAQRD +RLTGWLRANTTGDRQIRAAVPAGWTVGDKTGSGPLGERNDSGVLYPPDGAPLVLTVFTVP +ADADTARGEAAVAAAARAAI--- +>[subseq from] Beta-lactamase n=1 Tax=Stackebrandtia endophytica TaxID=1496996 RepID=A0A543AW05_9ACTN +--DISAEIADLEAQYGAVVGVYALDTATGQEI-AYRADDRFAYASTIKALAAAAVLHRPD +---TYLDELLTYTADDLVPHSPVTERHVDTGMTLGEVVDAAIRESDNTAGNLLFQRLGGP +EGLRAALRDIGDDTTTPTRWEPDLNGFEPGDDRDTSTAAALATSLLRYA-TEVLDEEDRT +TLITAMLGVRTGDGTIRAGVSAGWQVADKTGTGDHGTRNDIALLWSDEGDPVVLAVLTRS +VDPDGEPSDSLVAESTAIAM--- +>[subseq from] GES-22 n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=K0GF29_ACIBA +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPELGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 06-621-2 TaxID=2022500 RepID=A0A259XSL9_9NOCA +---AEKQFAALEQRFDARLGVFAVDLGSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD +AGTLSLTDTRIVEAEDKVPESAIDW-EAGQVVTLEQLCVAALTRSDNTAGNLLIDAVGGT +GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTDGPLSNSSRA +TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLGPDGRRILLVVLSRT +ANPDAAAMNELVADAVREIV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=A0A3N7VN92_9BURK +--AAQSQLDALEKASNGRLGVAALDTASGARI-GYRSRERFPVCATYAVVAVAAMLARST +LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT +QLTTWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ +PDAGAAPHADVVAAAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI0007591722 +--AAQSQLDALEKASNGRLGVAALDTASGARI-GYRSRERFPVCATYAVVAVAAMLARST +LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT +QLTTWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ +PDAGAAPHADVVAAAARIAA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0F7LGM5_ECOLX +--------------FGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADK------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ADI91-18 TaxID=1522755 RepID=A0A3N6CSM7_9ACTN +---LAGALGELEREHSARLGVFARNTATGRTV-AYRADERFPMCSVFKTLAAAAVLRDLD +RDGEFLARRIRYTAEEAEKYAVVTGRNVANGMTVEALCTAAVSESDNMAANLLLRELGGP +RAITRFSRSLGDRITGLERWEPELNSAEPWRTTDTTSPRAIGTSYGRLLLGDALDPRDRE +RLTGWLLANTTNGERFRAGLGPDWILADKTGGGNYGVTNDVGVVRAPDGPPIVMSVLSTK +PGPEGPRDNPLVAKTAALLAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Kushneria sp. YCWA18 TaxID=657387 RepID=A0A1S1NRK7_9GAMM +---VVERLKALERQHGSRLGVAICDIASGRCV-RHRANERFLLTSTGKVMAAALVLARVD +RGREQLTRRIRFEQQDLLEWSPITRQYAGPQMTLEALCRAAITHSDNTAGNLLLTSFGGP +TALTAYTRSLDDRVTRFDRIEPALNEDSEDDQRDTTTPWAMLGNLRKLLFADALSSASRH +HLSAWLVESQTGSDRLRAGMPDTWLIGDKTGTNASGAVSDIGVAWPGHRGAMLVTAYCHL +PAASKEERDGVIAEIGRLTA--- +>[subseq from] Carbapenemase n=1 Tax=Escherichia coli TaxID=562 RepID=H6U588_ECOLX +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] GES family class A beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI00106B09BB +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 852002-51564_SCH6189132-a TaxID=1834103 RepID=UPI0007EC1320 +---VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA +EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP +GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAELPAPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075DA37B +--AAQSQLDALEKASNGRLGVAALDTASGARI-GYRSRERFPVCATYAVVAVAAMLARST +LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT +QLTTWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ +PDAGAAPHADVVAAAARIAA--- +>[subseq from] Class A beta-lactamase n=23 Tax=Bacteria TaxID=2 RepID=Q6RSM8_ECOLX +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] BlaGES-5-like extended-spectrum beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A2THF2_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium sp. CBMA 234 TaxID=1918495 RepID=UPI001390A194 +---AATEFADLEDRYQAIIGVYGVDVVSSATV-EHRPDERFAMCSTFKAYAAARILQLSQ +DGKVDLDASVRISAGDIVVYSPVVSRAVGSSLPLRDICAAALQQSDNAAGNIMLRTIGGP +SAITDFARSIGDSQTRLDRWEPDLNTALPGDLRDTTTPRALCGGYRAILVGDALRPSDRF +QLQQWMLANTTSTKRFRAALPSGWTSADKTGSGDYGSSNDAGLLSGPTGERVMLTVLIRS +RTKDSGLFDEAVAATARLALD-- +>[subseq from] Beta-lactamase n=1 Tax=Brucellaceae bacterium VT-16-1752 TaxID=2487907 RepID=A0A3P1UFL7_9RHIZ +---VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD +RGEEKLDRRVFFGEKDLVIPFKATKPHLADGMTIEQLCEAAAIVSDSTAANLLMASFGGP +SALTAYLRSIGDQTTRIDKTELALNIVKPGETHDTTSPRAMVGTLQRIVLGSALSPTSRA +HLTEWMMASRDAAQRLRAGLPAGWRIANKPGTWEGIATNDIGVIFPPDRPPIVIAAYLGK +ARGSIVEQEAVLADVARIVTT-- +>[subseq from] Beta-lactamase L2 n=2 Tax=Sphingomonas sp. T1 TaxID=2653172 RepID=A0A653YUQ6_9SPHN +--------TDYEAASGGHVGIYARNLMTGRAI-AWRADERFVMCSTFKASLAACVLNRVD +RGRARLADRIALSPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLQRIGGP +AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMASTIGRLTRGPVLSPSSRA +LLMLWLRQCRTGDARLRAGLPRAWVIGNKTGNNGKDAAGDVGVLWRDPDTPIIISVYTRG +GTPTEAQFKTLFSEVARGVA--- +>[subseq from] Uncharacterized protein n=1 Tax=Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_38_11 TaxID=1798278 RepID=A0A1G0HC23_9GAMM +--TVSQRLNQLEIKNHVEIGLSAIETYNNTQI-NYHANKRFPMDSTSKLMTVSAILKKSE +TDPALLNRKIFFTMNDVKKYAPITVKHIKSGMTVSALCAAALEDSDNVAANQLMKILGGP +SKVTQFARSIGDEKFLLVRWEPALNSAIPNDKRDTTTPSTMTESIQKLVLGNALGKSQRQ +QLQVWLKHCKTGNHRIRAGVPDHFIVGDKTGTGGYGSIGDIGVVWRPQASPIVLAIYARQ +NEKKAQTPDKVIAKATKIVMN-- +>[subseq from] GES-9 n=3 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q49HG5_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGSRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Aeromonas media TaxID=651 RepID=UPI0009DDF7AC +-----------FEKQGWRVGVTVLDTKSGEHE-SINGDQRFHFNSTIKALACANVLEKVD +KGQLTLNDSFILKESDIVTHSPVAEKLVGKRFTLGDACEATLTYSDNTGANYAISSVGGP +AGLTSFMRSMGDNVLRSDRYEPELTKNIEYDIRDTTTTDAMALSLNKLLLQDVLSTESRA +QLKQWMMGNRVADDLLRASLPKGWSIADRSGASDYGVRGIISMVWSETQHPIVITMYVRK +EGSSIHERDKVIADIGSVIFGAy +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium HGW-Alphaproteobacteria-16 TaxID=2013662 RepID=A0A2N3D0A7_9PROT +-------LDRIREETGGRLGVAVFDSDSGRRF-FDGAEARFAMCSTFKMPLAAAVLARAD +RGEIDLNREIRFGEADLLEYAPVVRANLAKGLPIDTLLEAAVTVSDNAAANLLFGQVSGP +RGLTAFIRDAGDVVTRSDRYEPELNVVRGGEVRDTTTPMAMLWLMNAVLLGDVLSPASRA +KLIGWMEAASTGKERLRAGLPKGWRVGDKTGTSGEGYFNDIAIATPPGRKPILIACYLDA +PGLDGAKGNAVHRQVGELVG--- +>[subseq from] Beta-lactamase GES-4 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q764B7_KLEPN +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRTAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis flava TaxID=1507287 RepID=A0A1T4ZU88_9SPHN +----AGRLAALERQAGGRLGALFLDAASGRVT-GHRADERFALCSTVKWPLAAVILKAVD +AGTVSLEQPIRFGKSDLLSNSPRTRDNLAKGMSVAELLEATITVSDNAAANLLLPLVGGP +EAVTRQFRAWGDPVTRLDRAEPMLNLVGEGEVRDTTTPAAMAALLRTILLGDVLSHASRK +RLTDWGTATTTGPKRLRAGLPASWRLGHKTGTAMMNKYNDIAIAFPPEGAPLLIAVYYEG +PVTIRSEDEAVLAAAGKLAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium aubagnense TaxID=319707 RepID=A0A5R8SJ61_9MYCO +------SFEDLEDRYQALIGVYAVDLESSATV-EHRADERFAICSTFKAYAAARILQMAK +TGHANLDAMVPITAADIVVNSPVLSPAVGARMALRDICAAALTQSDNAAGNIMLRTIGGP +SAVTDFARSIGDSQTRLDRWEPDLNDAAPGDLRDTTTPRALCGGYRAILVGDALPGASQY +QLQRWMSETTTSTRRFRAGLPAEWTSADKTGSGDYGSTNDAGMLIGPKHERVMLTVLIRT +RTRDAGPFNEAVAESVRSV---- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=uncultured soil bacterium TaxID=164851 RepID=M4QA56_9BACT +---------------DARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEGIKLQDHFCASALPAGWFIADKSGAGE-------------------------- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A519J0Z1_9CAUL +------DLSALEARHGGRLGVSALDIAFNRSV-SWRGQERFAYCSTFKLFLAAAALERVE +RGEERLDRSIRITRADMISHAPVTGPAVGRGLTVQALCQAMVEVSDNPAANIMIREMGGL +NAWRDWLRTLGDTSTTVNRWEPDLNSAMADDPRDTCLPDQTVGNLREVLLDERLTAGHRR +LLEDWMLASPTGPNRIKAAAPTGWTVAHKTGTGANGATNDIGLLRPPSGQPVLVAAYFTE +APATTAQREAVLAQGV------- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio tasmaniensis TaxID=212663 RepID=A0A1A6IYT1_9VIBR +-----QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE +NEGLDLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLSGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNMLSQESKL +KLKSWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE +TEFTIQERDKVINEIGQLIFDAy +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium rhodesiae TaxID=36814 RepID=A0A1X0J5I5_MYCRH +---VEQRIADLEKRHNAFVGLYAQNLDSKVDL-AHRDGDPFAMCSTFKSYLSARVLQKAQ +AGELRLTDTMLVDPAELKPNSPRTEPNAGQPMAIADLCAAALQVSDNTAANMLLRTIGGP +PAITAFARSIGDDRTRLDRWETELNSAVPGDPRDTSTPRALGGGVARVLTGDVLDGPHRT +QLQDWMRANTT--SSMRGGLPAGWTTADKTGSGDFASTNDVGIAFGPNGERVLLAIMTRT +RSAQAEPLRQLIAEVATLA---- +>[subseq from] Beta-lactamase n=23 Tax=Bacteria TaxID=2 RepID=A0A127SUT1_9BACT +------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTHKVFTAAELLRQKN +--TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV +ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK +LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR +TEKNAKSDDAMIAEAAKRIFD-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia ninae NBRC 108245 TaxID=1210091 RepID=A0A511M8T2_9NOCA +--RATAQVRDLESAHHARVGAFAVDTKTGVFL-GYRENERFPIGSTFKTLAVAALLREHP +LADGYFDTVIHFTADDLVKYSPVTETRVGTGMTVRELAAAAIEKSDNTATNELLKLLGGP +TSITKFVRTLGDTTTSLDDWEPLSNSGDTNPEHNSTTPAALAADYRALVSGDALPTPERE +QLIEWLLRSTTGLNRIRAGLPQDWKTGDKTGGGDYGLTNDAAVTWPPNSSPIVITVLSIN +TEEHAPADDPLVAQSAKAITE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium DCM004Carb02 TaxID=1471931 RepID=X2KZB4_9BACT +------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTHKVFTAAELLRQKN +--TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV +ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK +LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR +TEKNAKSDDAMIAEAAKRIFD-- +>[subseq from] Class A beta-lactamase GES-25 n=1 Tax=Citrobacter freundii TaxID=546 RepID=A0A0M4NJD6_CITFR +---FKTDLERLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Caballeronia humi TaxID=326474 RepID=UPI00117D7380 +------PLADIEHRHGGRLGVYAIDTGTGHTL-EHRADERFLMCSTFKGMLAAQVLARVD +AGKERLDRLVQYTAQDLIFTSPVTKANVARGLPVHTLCQAIIEQSDNTAAILLMRGAGGP +AALTQFMRGIGDEVTRSDRYEPDSNRY--SGVLDTTTPRAIATAARAVLLGDVLRPASRA +QLERWMIDCKPGLNRLRAVLPAGWLAADRPGTSVEEQTNDYALVRPPGRAPLLVAAYYDA +PGMSMDEREAVLREAGKVFV--- +>[subseq from] Class A beta-lactamase GES-28 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0M5JBM2_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRNTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5L065_9BACT +------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTHKVFTAAELLRQKN +--TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV +ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK +LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR +TEKNAKSDDAMIAEAAKRIFD-- +>[subseq from] Carbapenem-hydrolyzing extended-spectrum beta lactamase GES-16 n=1 Tax=Serratia marcescens TaxID=615 RepID=D9IR25_SERMA +---FKTDLEKLEREKAAEIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Comamonas sp. 26 TaxID=2035201 RepID=A0A2G6ZPX0_9BURK +---LSDELAALEVQAQGRLGLYALDTSSGAAA-GWRSDERFAMCSTFKTLLVAHVLSLAQ +SGQIKLWHKRYYATTEVVAWSPVSAKWAGANMTLLDLCEAAVVVSDNTAANVLLESTGGP +AALTQWLRSLGDSITRLDRNEPTLNTALTGDERDTTTPEAMLLSLQKILLADVLDGSSRA +LLHQWLLDSRTGDKRVRLGLPAQWTIGGKTGSGDNGTSCDTLIAWPTQQAPVLVTAYLTG +SKLDLAGREAVLAKAGEAL---- +>[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea sp. NEAU-YG30 TaxID=2249762 RepID=UPI000DE34C54 +--QARKELRELEASFQGRIGAYALDTATGKAV-TYRPGERFPLLSTHKAILGAAMLHKAR +TEPGLMNKVLKWTAADLKPNSPTTEKHVADGLTVAQLCEATITLSDNTAANVLLKELGGP +PALTRYFRTLKDPISRLDRWETELNNWTVKEKRDTSTPAAIGRDLRALTAGNALNAKDRE +QLNAWLIANKTGDERIRAGLPKGWTIGDKTGTNTIGAGHDIAVIWPGRSAPIIMVVFTNR +EV--AAVDNKVIAQVATILA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium aichiense TaxID=1799 RepID=A0A378UKR9_9MYCO +----GQRIADLEKRHNAFVGLYAQNLDSKLDL-AHRDGDPFAMCSTFKAYLSARVLQKAQ +AGELLLTDTVLVDPAELKPNSPRTEPNAGQPMAISDLCAAALQVSDNTAANMLLRAIGGP +PAITAFARSIGDDRSRLDRWETELNTALPGDPRDTSTPRALGGGLARVLTGDVLDGSHRK +QLEDWMRANTT--SSMRAGLPAGWTTADKTGSGDFASTNDVGIAFGPGGERVLLAIMTRT +QSDDAAPLRQLIAEVATLA---- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Vibrio antiquarius (strain Ex25) TaxID=150340 RepID=A7K2A8_VIBAE +-----------------------WDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD +SGKLSKNATAKIDERSIVVWSPVMDKLAGQSTRVEHACEAAMLMSDNTAANLVLNEIGGP +KAVTMFLRSIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV +QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE +TELSLQARDQLIAQISQLILQKy +>[subseq from] Extended-spectrum beta-lactamase GES-17 n=1 Tax=Escherichia coli TaxID=562 RepID=F2YBS7_ECOLX +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sphingomonadales bacterium TaxID=1978525 RepID=A0A4Q5T0F8_9SPHN +-------FDRIRAETGGRLGLAVYDTGTGRRF-SDGAEARFAMCSTFKVPLVAAVLARVD +RGELNLASEIRFGEADLLDYAPVVKANLAKGMSIDALCEAAVVMSDNSAANLLFGQISGP +RGLTKFIRDAGDQLTRSDRDEPSLNRVRDGEVRDTTTPDAMLWLMNRLLLGDVLSAASRA +RLTGWMEASPTGKARLRAGLPKDWRVGDKTGTSGEGYFNTIAIATPPGRKPVLIACFLDA +PGLETAKANAAHAKV-------- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C85AB49 +-----QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE +NEGLDLGLKVGIESDDLIVWSPVTKHLVGKDLSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE +TEFTIQERDKVINEIGQLIFDAy +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp8963 TaxID=2184547 RepID=A0A3N8KZS3_9BURK +--AAQTQLDALEKASDGRLGVAALDTASGARI-AYRSREHFPMCGTYAVVAVAAMLARSA +LDESLLPRRILYRRYDVVSGSPVTESHVDTGLTIEQLCIAVLQSGDKAAGNLLMGVLGGP +QAVTGFAHTSGDTLFRLDRWEPELNTAAPGDDRDTSTPLAMTETLRRLLLGDTLGEPQRT +QLTKWMVGNPGGGARIRAAVPSDWRVADMAGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ +PRADAAPRADVVASAARLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter senegalensis TaxID=446692 RepID=A0A0U5EZX7_9PROT +-------ISQHENETGGHVGFYAENTQTGATL-GWRTDERFVMCSTFKASLAACVLARVD +KGLDTLERPLSYTAADIGDYAPVAKANQAKGMTIRELCAGAVEQSDNTCANLLLTHIGGP +SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGPVLSAPSRT +ILTDWLIRCRTGEHRLRAGLPNEWKIGDKTGNNGKDAAGDIAIIWPTPETSIVVCAYTRG +GHPTEQQLSSVFAGIGKLVA--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SF73_9BACT +--DFAAKIVQLEQEKQARIGVAVTDQAGRTVL-GHRENERFALCSTFKLPLVAQVLWRID +QGREKSSRPLAYNVDALQEYAPVARRYAPSGMTVQEASLAALQWSDNTAANLLLDTLGGP +AGFTRFVRQNGDSTTRLDRPEPDLNSNQPDDPRDTTTPLAMSRLTSRLLWGNTLRPATRQ +QLQRWLIGNSTGDTTIRAGLPAGWLAGEKTGSCELGGRNDAGFVRSPAGKNHALAIYTLA +PQLEPKERDALIAETARLVTA-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. Chr-9 TaxID=713612 RepID=UPI00068AE595 +---VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRANERFAICSPFKVYAAAAILRLEA +EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP +GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia acidipaludis TaxID=660537 RepID=UPI000486431A +-------LAAIERRHGGRLGVFAIDTASGRTL-AWRADERFLMCSTFKGLLAALILARVD +AGQESLARLVRYTEQDLIFTSPVTKAHVGEGMTVGALCQAVVEVSDNTAAILLMRSAGGP +AALTRFARSMGDTVTRFDRYEPDSNRY--SGLLDTTTPRAITQSARSLLLGDALSLQSRR +QLENWMIACKPGLNRLRAALPADWLAGDRPGTSVERETNDYAIVRPPGRGPLLVAAYYDA +PGLAMDRREAVLREAGSVFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudescherichia vulneris TaxID=566 RepID=UPI0012AC52BF +---LQAFLKQEETRLPGKIGMSIVNADGQPIF-GYRQNERFPLTSTFKVLACGALLDRLH +KTAGSLDETVTIKPDELLSYSPITKNYVAPAITLQTLCSAAVSYSDNTAGNSILTYLGGP +VAVTRFMRESGDTVTRLDRTEPTLNEATPGDERDTSTPERMASGLHTLLATPLLTKPHQA +MLESWMREDKVADNLLRAALPKGWTIADKTGAGGYGSRAIIAAVYPTGEKPFYMAIYITQ +TDAEMKVSDGVIKKIGERVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C8429B9 +-----QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE +NEGLDLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNNMVVTLNELVYGNTLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE +TKLTIPERDTVINEIGELIFDAy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A399N0R8_9MICO +--AADAAFAALEERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--VAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDITAANLLLEALGGP +AELDAALTVLGDDTTVVSRTEPDLNQAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPADWTVGDKSGLGAYASRGDVAVIWRPDAAPIVIAVHSAK +DRQDADADDALISGAAKAAAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. PS03_16 TaxID=2559611 RepID=A0A4Y9MIQ8_9MYCO +------GLEALERANSAVIGVFGTNLDTGRTV-AHRAQESFAMCSTFKAYLAGLVLSLVD +RGERSLDQRLYVDPAELQPNSPRTGPRAGGEMTLDELSQAVLQVSDNAAANILLHNVGGP +PAITGFARGIGDPRSRLDRFEIELNSAVPGDPRDTSTPEAMAGGFRALLTGDVLTPARRQ +LLGDWMRANET--SSMRAGLPTGWTTADKTGSGDYGTTNDVGIAYGPKGQRVLLAVMTRS +ATPDAENMRPLIGEVTAAVF--- +>[subseq from] Beta-lactamase GES-6 n=4 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A088DDJ8_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C8648AB +-----QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFD +NEGLDLGLKVGIGSDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLSGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNMLSQESKL +KLKSWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWRENRAPLIISISLTE +TEFTIQERDKVINEIGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium rhodesiae TaxID=36814 RepID=UPI0009F1D972 +---VEQRIADLEKRHNAFVGLYAQNLDSKVDL-AHRDGDPFAMCSTFKSYLSARVLQKAQ +AGELRLTDTMLVDPAELKPNSPRTEPNAGQPMAIADLCAAALQVSDNTAANMLLRTIGGP +PAITAFARSIGDDRTRLDRWETELNSAVPGDPRDTSTPRALGGGVARVLTGDVLDGPHRT +QLQDWMRANTT--SSMRGGLPAGWTTADKTGSGDFASTNDVGIAFGPNGERVLLAIMTRT +RSAQAEPLRQLIAEVATLA---- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudodonghicola xiamenensis TaxID=337702 RepID=UPI00040728EF +---SAERLREIEQVLAARVGVFARNIDTGAEF-SHRAGERFAMCSTFKASLAALCLQRAD +RGELDLDERLSLNGVRLLPTSPVTSQQPPSGLDIRTLCKAIVERSDNTAANLLLDRVGGP +AAVTEFFREIGDDVSRLDRTEMALNANTQGDPRDTTAPEAMARTVERLALGTVLSEGARQ +QLVAWMRNEQNAKDRIRAAVPGSWTVANKPGTTPNGAANDIAALWSPNGPRFVLAIYIDT +RLDRLRPSVTAIRDVAQIALRH- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A2Z6TA99_BURVI +----RSELAALDKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP +QAVTAFAHESGDTVFRLDRWEPGLNRAAPGAERDTSTPVAMVDTLQRLLLGDTLQQAQRT +QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAGSFTQ +AQADAAARADVVASAARIAT--- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012D8B6E9 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDIKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNSQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLNMAERNQVIVEVGNAIFKEf +>[subseq from] ACI family class A beta-lactamase n=1 Tax=Selenomonas bovis TaxID=416586 RepID=UPI00036827FC +------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTLKVFTAAELLRQKN +--TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV +ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK +LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR +TEKNAKSDDAMIAEAAKRIFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas aerolata TaxID=185951 RepID=UPI00141ADE4D +-------VADYETASGGHVGLYARNLTTGRAI-AWRADKRFVMCSTFKASLAACVLNQVD +RGRARLADRIALSPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLRQVGGP +AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMALTIGRLTRGPVLSPSSRA +LLMLWLRQCRTGAARLRAGLPRGWAIGNKTGNNGKDAAGDVGVLWRDPDTPIIISVYTRG +GTPTEAQFKTLFSEVARGVA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. Chr-9 TaxID=713612 RepID=A0A0B1RF66_9NOCA +---VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRANERFAICSPFKVYAAAAILRLEA +EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP +GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium mucogenicum TaxID=56689 RepID=A0A1A3GX92_9MYCO +------SFEELEDRYQAIIGVYAVDLESSATV-EHRPDERFAICSTFKAYAAARILQMAK +AGQANLDAMVPITAADIVVNSPVLGPAVGARMPLRDICAAALTQSDNAAGNIMLRTIGGP +SALTDFARSIGDSQTRLDRWEPDLNEAAPGDLRDTTTPRALCGGYRAILVGDALPGAAQF +QLQRWMGETATSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGMLIGPKRERVMLTVLIRT +RTRDAGPFNEAVAECVRSVL--- +>[subseq from] Class A carbapenem-hydrolyzing beta-lactamase GES-39 n=2 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A346MLH3_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVGWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Class A beta-lactamase GES-34 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A2I6PAY4_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRNEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia sediminicola TaxID=458836 RepID=A0A419TJC7_9BURK +------PLADIERRNGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLSRVD +AGKEDLARLVRYTEKALVFTSPVTKAHVAQGMSVGALCQAIVEVSDNTAAVLLMRGAGGP +AGLTQFVRSLGDTVTRSDRYEPESNKY--SGVLDTTTPRSITKSASQILLGNVLSPQSRA +QLENWMIACTPGLNRLRAALPPDWIAGDRPGTSVEEETNDYAIVRPPGRAPLLIAAYYDA +PALAMPAREAVLREVGAAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Sandarakinorhabdus limnophila TaxID=210512 RepID=UPI000A031AB7 +--ALRRAITAVERSAGGPIGISLLDTHTGERF-GHRADDRFPLCSTFKLLLAARLLHGAD +KGQWAMTERLPVTKADMLFNAPFTEKRIGGTASLLELAQAMAVLSDNPAANIALAKVGGP +AALTAWLRSIADQTTRIDRNEPEMNNETPGDPRDTTTPAAMLATSRALVEGRILSPAARR +TLFGWMQASKTADTMIRAALPPGWQEANKTGAGSWRARNIVSVITPPGRKPIWVAAYLFA +ARSELAERNRQFVPLGRAIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 14-2483-1-1 TaxID=2023148 RepID=UPI000B9C1449 +---AEQAYLELEARDTARLGVNALDLATGSTQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGKLQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSLAAGYRSLLDGDVLTEASRK +QLLEWMGDTETSTARFRAGIAPKWTSADKTGTGSYGVSNDAGLLFGPDGQRILLVVLSAT +TSEDSPAMNPLVADATRAAVE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=A0A118Q0Q8_BURPY +--AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARSA +LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QAVTAFAHGSGDTSFRLDRWEPALNTAAPGDERDTSTPLAMAESLRRLLLGDVLREPERT +QLTKWMLGNTSGFAGIRAGVPSDWRVAGVGGAGGYGTTTDVAVLWPASRAPLVMAVSFTQ +PDAGAAPHADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. 360MFTsu5.1 TaxID=1172186 RepID=UPI0012DFAC03 +------SFEELEDRYQAIIGVYAVDLESSATV-EHRPDERFAICSTFKAYAAARILQMAK +AGQANLDAMVPITAADIVVNSPVLGPAVGARMPLRDICAAALTQSDNAAGNIMLRTIGGP +SALTDFARSIGDSQTRLDRWEPDLNEAAPGDLRDTTTPRALCGGYRAILVGDALPGAAQF +QLQRWMGETATSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGMLIGPKRERVMLTVLIRT +RTRDAGPFNEAVAECVRSVL--- +>[subseq from] Beta-lactamase n=1 Tax=Bordetella holmesii TaxID=35814 RepID=A0A5Q1WZJ3_9BORD +------------------------------TT-GFRADERFALCSTFKVLAVGAVLARVA +RGEDDLSRPMRLSAADIVAHSPVTQQRLNEGMTLGQLCDAALVVGDNTAANLLLSTIGGP +PGVTAYARSLGDAVTRLDRLETALNDATPGDDRDTTSPVAMAENLRQLVLGDALPGPERE +RVRDGLLHCQTGKGRLRAGLPAAWTFGHRTGAGGHGTCNDIGIAWPPSAGPVVISAYLTE +SPLPLPERERVLAEAGRIVVH-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075AD78C +--AAQSQLDALEKASNGRLGVAALDTASGARI-GYRSRERFPVCATYAVVAVAAMLARST +LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT +QLTTWMLGNTRSFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ +PDAGAAPHADVVAAAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=A0A2J6U845_9VIBR +-----KSIEKIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYNFE +NEGLNLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGSYGSRAITAMVWSENRAPLIISISLTE +TELTIQERDTVINEIGQLVFDAy +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 06-1477-1B TaxID=2022485 RepID=A0A260F898_9NOCA +----EQPYSQLEARDTARLGVSALDLTSGSLQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVVTLADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNLMAAGYRTLLDGDVLTQASRQ +QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQRILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. 7MH5 TaxID=2547399 RepID=A0A4V1AZZ5_9BURK +--AAESPFADLERRNGGRLGVFAIDTGSGRTL-AWRADERFLMCSTFKGLLAAQILARID +AGQEHAERQVRYTEQDLIFTSPVTKAHVAHGMTVGALCQAAVEVSDNTAAILLMRSAGGP +QGLTQFVRGLGDSVTLSDRYEPHSNQY--SGALDTTTPRAIAQSARKILLGNVLSAQSRQ +QLEDWMIASTPGRARIRAALPADWRAGDRPGTSVERETNDYAIVRPPGRAPLVVAAYYDA +PGLDMARREDVLRDAG------- +>[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis subsp. tessellarius TaxID=31965 RepID=A0A154V1B0_9MICO +--AADAAFTALEQRFGARLGVHAIDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMERAVPIEAADILAYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPTLNEAIPGDDRDTTTPRAAAALMRAYALGGPLDDDERA +LFTGWLTATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDAAPIVIAVHSSK +QQQDAVADDALVSGAANAAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia sp. TaxID=1884818 RepID=A0A352MR92_9ESCH +---LQAFLTQEETRLPGKIGMSIVNADGQPIF-GYRQNERFPLTSTFKVLACAALLDRLH +KNAGSLDQTVTINPDELLSYSPITKNYVAPAITLQTLCSAAVSYSDNTAGNSILTYLGGP +VAVTRFMRESGDTVTRLDRTEPTLNEATPGDERDTSTPERMASGLHTLLATPLLTKPHQT +MLESWMREDKVANNLLRAALPKGWSIADKTGAGGYGSRAIIAAVYPTGEKPVYMAIYITQ +TDAEMKVSDGVIQKIGERVF--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A525HJQ7_SPHSX +---FTAAVRKLEQGLGARIGLHLIDPVGGRTA-TWRGGERFPMCSTFKLLLAGMILHKID +HGSERLDRQIAVPSTGILPNSPTTAGQAGGHLGIGDLCEAAMTRSDNTAANLLLGTVGGP +EGLTRFLRSTGDMVTRLDRVETILNEGTPGDPRDTTTPNAMLDTLRRLTFGTVLAPDSRK +NLMLWLANNTTGTEKLRKGLPAGWAIGDKTGAGGHNSNNDVALIWPPGRQPIFVTVFITG +GPDEAPARNPVHARIGELIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus fascians D188 TaxID=1051973 RepID=A0A165LRG1_RHOFA +----EKNYVELEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGMLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLTQASRQ +QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQRILLVVLSAT +MSEDSPAMNALVADTTRMVVEQ- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00056BDF74 +--SAEQNYLELEARDTARLGVNVLDLATGSTQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGKLQLTDTRTITAEDKVPESAVD-WAPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSLAAGYRSLLDGDVLTEASRK +QLLEWMGDTETSTARFRAGIAPQWTSADKTGTGSYGVSNDAGLLFGPDGQRILLVVLSAT +TSEDSPAMNPLVADATRAAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00055D5304 +---AEKQFAALEQRFDARLGVFAVDLGSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD +AGTLSLTDTRIVEAEDKVPESAIDW-EAGQVVTLEQLCVAALTRSDNTAGNLLIDAVGGT +GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTDGPLSNSSRA +TLLDWMAGTQTSDTRFRAGVPTGWTTADKTGTGSYGVSNDAGLLLGPDGRRILLVVLSRT +ANPDAAAMNELVADAVREIV--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C8554C4 +-----QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE +NEGLDLGLKVDIESDDLIVWSPVTKHLVGKDLSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE +TEFTIQERDKVVNEIGQLIFDAy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. PsTaAH-137 TaxID=1305830 RepID=A0A327W6M8_9ACTN +--AAKDAFARLERTYRAHLGLYAIDTGNGREV-TWNDKRRFSYNSTVKSFLAAAVLKKNG +--SDGMDRVLHYDRADVIANSPVSEKHVDTGMSLRALCDAAVRYSDNTAANVLFKDMGGP +GRLGTFLKELDDRVTRTDRVEPFLSQWTPGERRDTSTPRQMAGDLRDLVLGDTLPTAERR +QLTTWLRNNTTGDTTIRAGVPKGWVVGDKTGTGYYGARDDIAVVWPPGRKPLVMAILTYR +DGKDTEADDKLLADAAKAAVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI000F80DD9C +--AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARSA +LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QAVTAFAHGSGDTSFRLDRWEPALNTAVPGDERDTSTPLAMAESLRRLLLGDVLREPERT +QLTRWMLGNTSGFAGIRAGVPSDWRVAGVGGAGGYGTTTDVAVLWPASRAPLVMAVSFTQ +PDAGAAPHADVVASAARIAA--- +>[subseq from] ACI family class A beta-lactamase n=1 Tax=Veillonella seminalis TaxID=1502943 RepID=UPI000F8F5492 +------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTHKVFTAAELLRQKN +--TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLKWSDNTAANLILQEIGGV +ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK +LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR +TEKNAKSDDAMIAEAAKRIFD-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhodococcus TaxID=192944 RepID=UPI000B9B7AC9 +--SAEQAYLELEARDTARLGVSVLDLETGSTQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPGDPRDTTTPDSLAAGYRTLLDGDVLTEASRK +QLLEWMGDTETSAARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT +TSEDSPAMNPLVADATRAAVQQ- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C82B3BE +-----QSIEQIESRVSARIGIAVYDSATKQTW-SYKGEERFPMMSTFKTLACANLLYDFE +NEGLNLGLKVDIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE +TEFTIQERDKVINEIGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00056447DE +---AEKQFAALEQRFDARLGVFAVDLGSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD +AGTLSLTDTRIVEAEDKVPESAIDW-EAGQVVTLEQLCVAALTRSDNTAGNLLIDAVGGT +GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTDGPLSNSSRA +TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLGPDGRRILLVVLSRT +ADPDAAAMNELVADAVR------ +>[subseq from] Beta-lactamase n=2 Tax=Rhizobium/Agrobacterium group TaxID=227290 RepID=A0A1M3PNJ1_9RHIZ +----ELRLKELETRSGGRLGVAVSNTATGQIV-GNRLDERFAMCSTFKALAVAYTLHRVD +RGDEHLDRRVFFNERDLVTPFKATKPHLADGMTIEQLCEAAIIVSDSTAANLLLASFGGP +LALTTYLRSLGDRVTRLDKIELDLNVVKQGETHDTTSPRAMVGTLRQVVLGDALSAPSRM +KLTNWMTESKDATQRLRAGLPKGWQIANKPGTWKGISTNDIGVIFPPGRDPLVVAAYLGG +APGKIKDQETILADVARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. S6 TaxID=1479623 RepID=UPI00068AF637 +---AAQRLRELESRLEGRIGVHAFNSQTQVRF-GYRSTERFLFCSVGKVLVVSTILDRAT +SDPSLLSRNIDITEEDILPYAPATGQHIGESMSVESLCEAAITLSDNTAANLLVETVGGP +NAVTDFVRRTGDVLTRMDRTEPELNDA--AGELDTTTPAAFCSTLENLALGTALTPEHRL +RLTTWLKANTTGADQIRAGVPAGTTVGDKTGAGTHGESNDVAVIWPKNGSPVVLSIFTTS +SIADQAAQKSAIAEATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Kitasatospora aureofaciens TaxID=1894 RepID=BLAC_KITAU +----SGRLRALEKQYAARLGVFALDTGTGAGR-SYRAGERFPMCSVFKALAAAAVLRDVD +ARREFLTKRIHYTEKFVKDYIPVTGKNIAGGMTGAELCAAAVSESDNGAGNLLLRELDGP +TGITRFCRSLGDTTTRLDRWEPALNSAEPDRVTDTTSPGAIGRTFGRLIVGSALRAGDRK +RLTGWLVANTTNRPTFRAGLPDDWVLADKTGGGEYGVANDVGVVQPPGRAPLVLSVLSTK +FDPKGPTDNPLVAKAAALVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 06-418-1B TaxID=2022515 RepID=UPI000B9BF328 +---AEKQFAALEQRFDARLGVFAVDLGSEVTT-TYRSDERFAFCSTFKVYAAGAVLAAAD +AGTLSLTDTRIVEAEDKVPESAIDW-EAGQVVTLEQLCVAALTRSDNTAGNLLIDAVGGT +GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTDGPLSNSSRA +TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLGPDGRRILLVVLSRT +ANPDAAAMNELVADAVREIV--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 06-156-3 TaxID=2022517 RepID=A0A260DMU9_9NOCA +---AEKQFAALEQRFDARLGVFAVDLGSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD +AGTLSLTDTRIVEAEDKVPESAIDW-EAGQVVTLEQLCVAALTRSDNTAGNLLIDAVGGT +GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTDGPLSNSSRA +TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLGPDGRRILLVVLSRT +ANPDAAAMNELVADAVR------ +>[subseq from] class A beta-lactamase n=1 Tax=Sulfitobacter geojensis TaxID=1342299 RepID=UPI000568C4B4 +------EIRALEKRHDARIGVMVRHPASGWHW-GHRENERFLMNSTFKSVLCAAILDQVD +RKALDLNAKIKISGQDILHYAPVTKKHIGSALPISDLCFATLDQSDNTAANLLINLLGGP +KGVMTYLDRINDAVTRLDRIEPSLNNFVAGDPRDTTSPAAMTTTWQKMLTGDALRPASRA +QLAEWMRHGSVTQEFLRKSAPAGWQIIDKSGGGRNHTRSYVAMITPLAGAPYFIAIYVSD +TPASWVERNAIVAGIGRAIID-- +>[subseq from] Beta-lactamase n=1 Tax=Komagataeibacter maltaceti TaxID=1203393 RepID=A0A2S3VYK9_9PROT +----PSVLSDYEHATGGHVGVCAHNIATGHKL-LWRADERFVMCSTFKASLVACVLSHVD +QGHDGLERVIPLTAADIQDYAPVAKAALAQGLSVGEMCEAAVEQSDNSCATLLLSRIGGP +SALTAFWRAMGDVTTRLDDPEPYLNRTPAGGVRDTTTPAAMAAIVQKLVLGTVLSASSRE +LLTRWMVGCQTGRNRLRAGLPANWVVGDKTGNNARDAAGDIAVAWPRPGTPIVICVYTRG +GTPTEQQFAALFSGVGRLVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Mycolicibacterium TaxID=2636767 RepID=UPI001323CFAE +---ASTEFADLEDRYQAIIGVYGVDVVSSATV-EHRPDERFALCSTFKAYAAARILQLSR +DGKVDLDASVRITAGDIVAYSPVVSRAVGSSLPLRDICAAALQQSDNAAGNIMLRTIGGP +SAVTDFARTIGDSQTRLDRWEPDLNTALPGDLRDTTTPRALCGGYRAVLVGDALRPSDRL +QLQQWMLANTTSTKRFRAALPSGWTSADKTGSGDYGSSNDVGLLSGPTGERVMLTVLIRS +RTKDSGLFDEAVAATARLALD-- +>[subseq from] Beta-lactamase n=1 Tax=Listeria rocourtiae TaxID=647910 RepID=A0A4R6ZSJ9_9LIST +--SVDKELKKLEEKYDVTLGVQGINLADNKQV-SYNEQERFAYASTYKAIAGGLLLKNLT +--EDQLNKRIKFSKEDLVDYSPVTEKHVEDGMTVKELINAAMMYSDNTAGNVLFDQLGGP +KGYQKELAKIGDKTTQADRIEPELNEAKPGDKRDTTTPEAMAKGLSFLATEGNMAANRLD +YFKQTLIDNTTGDKLIRAGVPDGYAVGDKTGAGSYGTRNDIAVIYPKGKKPLVWVIFSKK +AGKDDKYDDQLIADTAKVLSDFf +>[subseq from] Extended spectrum beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=C8ZLL4_ACIBA +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGACANGARNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012DAF0A6 +--SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS +VGGIDKYKITSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP +SSLTQFLRAMGDIKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNSQDEQ +TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ +TKLDMAERNQVIVEVGNAIFKEf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces caatingaensis TaxID=1678637 RepID=A0A0K9XAM5_9ACTN +-------------QVPVRLGVFAYSPAGGTTV-EHRAGEAFPMCSTFKTLAVAAVLRDLR +QGDRFLHERVRYPRRDTEEYAPVTGRNLRDGMTGAELCGAAVSYSDNCAANLLLRRLGGP +GGVTRFCRSLGDDDTRLDHWEPALNSAVPGAVEDTTTPRAIALTYARLVLGNALPARHRE +RLTGWLLANTTGRNQLRAGLPRDWALGDKTGAGKYGTNNDVGVAWPPGRPPVVLSVLTTT +GDLDKTKTDVLIAETAALL---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02120-2 TaxID=2020327 RepID=A0A2M9KD91_9ACTN +---LAGALGELEREHSARLGVFARNTATGRTV-AYRADERFPMCSVFKTLAAAAVLRDLD +RDGEFLARRIRYTAEEAEKYAVVTGRNVANGMTVEALCAAAVSESDNMAANLLLRELGGP +RAITRFSRSLGDRITGLERWEPELNSAEPWRTTDTTSPRAIGTSYGRLLVGDALDPRDRE +RLTGWLLANTTNGERFRAGLGPDWILADKTGGGNYGVTNDVGVVRAPDGPPIVMSVLSTK +PGPEGPRDNPLVAKTAALLAQ-- +>[subseq from] class A beta-lactamase n=2 Tax=unclassified Mycolicibacterium TaxID=2636767 RepID=UPI0012DF9D13 +---ASTEFADLEDRYQAIIGVYGVDVVSSATV-EHRPDERFALCSTFKAYAAARILQLSR +DGKVDLDASVRITAGDIVAYSPVVSRAVGSSLPLRDICAAALQQSDNAAGNIMLRTIGGP +SAVTDFARTIGDSQTRLDRWEPDLNTALPGDLRDTTTPRALCGGYRAVLVGDALRPSDRL +QLQQWMLANTTSTKRFRAALPSGWTSADKTGSGDYGSSNDVGLLSGPTGERVMLTVLIRS +RTKDSGLFDEAVAATARLALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas sp. FA1 TaxID=1346710 RepID=UPI00128E09BC +--DVAAALADVEARHGVRLGVHALDTVTGATA-SHRADERFAFCSTVKPLAAAAVLAAR- +-GVAGVDERVPVEADDLVTYSPVAEQRVGVGMTWRELVGAALRFSDNTAGNLLLAGAGGP +AALTAWLRGLGDDVTRSDRTEPELNAYAPGDDRDTSTPRALAGTYRALVVGDVLGGPERD +LLTDAMLRSTTGDALVRAAARPGWEVADKSGAGAYATRNDVAVVWTPAGAPVVLAVLSDR +ADPAAERADAPVAQAARVVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000F577904 +--AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST +LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT +QLTKWMLGNTRGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTARAPLVMAVSFTQ +PDAGAAPHADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI0007542C75 +--AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST +LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT +QLTKWMLGNTRGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTARAPLVMAVSFTQ +PDAGAAPHADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium sp. CBMA 226 TaxID=2606611 RepID=UPI00130CC581 +-------FEELEDRYQATIGVYAVDLESSATV-EHRTDERFSICSTFKAYAAARILQMAQ +AGHANLEAMVPITAADIVVNSPVLSQAVGSQMALREICAAALTQSDNAAGNIMLRTIGGP +SAITDFARSIGDSQTRLDRREPDLNDAAPGDLRDTTTPRALCGGYRAILVGDALSGPGQF +QLQRWMSETATSTKRFRAGLPAGWTSADKTGSGDYGSTNDAGILIGPKRERVMLTVLIRT +RTRDAGPFNEAVAESVRSV---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075FB41A +--AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST +LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT +QLTKWMLGNTRGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTARAPLVMAVSFTQ +PDAGAAPHADVVASAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacteriaceae bacterium 1482268.1 TaxID=1834080 RepID=A0A1A0MU39_9MYCO +-----DRIEALQRRYQAKIGVYAVDLASGRTV-SHLDGESFAICSTFKAYAAARVLQMAQ +SRELSLDRPVFVDPVQAALNSPRTAPNAGGQMPLAELCAAAVQVSDNAAGNLLLQTIGGP +SAITDFARSIGDEQTRLDRWETELNSATPGDPRDTSTPNALGGGFRSLLAGDVLAPPQRQ +QLEEWMRANET--SSMRSGLPSGWTTADKTGNGDYGSTNDVGIAYGPGGEKLLLAIMTRA +QAEDAPNNRPLIGEVAAALV--- +>[subseq from] Class A beta-lactamase n=2 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0C5L1Y2_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] GES-1 n=22 Tax=Bacteria TaxID=2 RepID=D3U0R3_ECOLX +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium sp. CBMA 226 TaxID=2606611 RepID=UPI0012DF8013 +-------FEELEDRYQATIGVYAVDLESSATV-EHRTDERFSICSTFKAYAAARILQMAQ +AGHANLEAMVPITAADIVVNSPVLSQAVGSQMALREICAAALTQSDNAAGNIMLRTIGGP +SAITDFARSIGDSQTRLDRREPDLNDAAPGDLRDTTTPRALCGGYRAILVGDALSGPGQF +QLQRWMSETATSTKRFRAGLPAGWTSADKTGSGDYGSTNDAGILIGPKRERVMLTVLIRT +RTRDAGPFNEAVAESVRSV---- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Mycobacterium TaxID=2642494 RepID=UPI000491F0AB +------SFEELEDRYQAIIGVYAVDLESSATV-EHRPDERFAICSTFKAYAAARILQMAK +AGQANLDAMVPITTADIVVNSPVLGPAVGARMPLRDICAAALTQSDNAAGNIMLRTIGGP +SALTDFARSIGDSQTRLDRWEPDLNEAAPGDLRDTTTPRALCGGYRAILVGDALPGAAQF +QLQRWMGETATSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGMLIGPKRERVMLTVLIRT +RTRDAGPFNEAVAECVRSVL--- +>[subseq from] Beta-lactamase GES-3 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q767E8_KLEPN +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRTAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas aerolata TaxID=185951 RepID=A0A2T4YM04_9SPHN +-------VADYETASGGHVGICARNLTTGRAI-AWRADERFVMCSTFKASLAACVLDRVD +RGRARLADRIALVPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLRQVGGP +AALTAYWRRLDDDVSRLDDIEPFLNRTLPGGLRNTTTPRAMAATIGRLTRGPVLSPSSRA +LLMLWLRQCRTGAARLRAGLPQGWVIGNKTGNNGKDAAGDVGVLWRDPDTPIIISVYTRG +GSPTEAQFKTLFSEVARGVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C8556DC +-----QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE +NEGLDLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPDDVRDTTTPNSMVVTLNELVYGNTLSQESKL +KLKNWMIGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE +TEFTIQERDKVINEIGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C831654 +-----QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYNFE +NEGLNLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TKLTIPERDTVINEIGELIFDAy +>[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia sediminicola TaxID=458836 RepID=A0A495GZV1_9BURK +------PLADIERRNGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLSRVD +AGKEDPARLVRYTEKDLVFTSPVTKAHVAQGMSVGALCQAIVEVSDNTAAVLLMRGAGGP +AGLTQFVRSLGDTVTRSDRYEPESNKY--SGVLDTTTPRSITKSASQILLGNVLSPQSRA +QLENWMIACTPGLNRLRAALPPDWIAGDRPGTSVEQEANDYAIVRPPGRAPLLIAAYYDA +PALAMAAREAVLREVGAAFV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=S5YYN5_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGELVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050CB579 +----EQNYLELEARDTARLGVNVLDLATGSTQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGKLQLTDTRTITAEDKVPESAVD-WAPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSLAAGYRSLLDGDVLTEASRK +QLLEWMGDTETSTARFRAGIAPQWTSADKTGTGSYGVSNDAGLLFGPDGQRILLVVLSAT +TSEDSPAMNPLVADATRAAVE-- +>[subseq from] GES-type beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A2Z6FKN6_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKETEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase GES-18 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=H2ERK4_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALIFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Sodalis praecaptivus TaxID=1239307 RepID=W0HZX8_9GAMM +----QPYLQKEENRLNARIGVAILDAHGQRIF-GYRSEERFPLNSTHKVLACAALLANAR +QHSALLEQHVTIMPQALVDYSPITQTRLAPGFTLRELCRAAVSYSDNTAANSILEVIGGA +GAVTRFMRLIGDNVTRLDRLEPSLNEAVPGDVRDTTTPASVVAALRTILATDVLTLPHRQ +LLQTWMMDDQVAGDLLRASLPTGWRIADKTGAGGYGSRSIIAAVYPDPKQPFYIAIYITQ +TAATLQQSNRVAANIGKIIF--- +>[subseq from] class A beta-lactamase n=1 Tax=Frigoribacterium sp. PhB116 TaxID=2485174 RepID=UPI00105DFBEF +--DVADDLAALEAEFDARVGVSVVDTETGTTA-SHRADERFGYASSIKALAAAQLLHDVP +--AEQRDEVVTWTAADVEAYSPVTSEHVADGLTRAQLAEAAVRKSDNTALNIVLDRVGGP +AGLDQGLEDIGDTTTEVVNREPELNTIEPGSTDDTSTPAAFTADLGALLDGRWLDDPDRA +LLLDWMSGNATGDTLIRAGAPDGWVVADKSGGAG-GIRNDVAVVTPPGRAPVVVTVFTTR +NDPDARYDDALVARAAAIVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis ganjiahuensis TaxID=239984 RepID=UPI000592D0AE +---YAAEFEALEEEFDARLGVYALDTGSEAEV-AFRADERFGFLSTFKALLVGVVLSENS +--LEEMDRVVEYGEEDLVDHSPVVEENLGSGMSLMELSDATVRFSDNAAANLLLEEIGGP +EGFGESLVETGDEVTNPVRWETELNDVGPGDDRDTSTPEALVGSLEAFTLGDVLPEDRRE +VLVDLLVRNTTGDELIRAGVPEGWVVGDKTGGGG-GMRNDVAVVWPEEGDPIVMAVLTTR +NEEGVEFDNALIAEATEVVVE-- +>[subseq from] GES-type beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A2Z6FKM9_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPKMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 283mftsu TaxID=1761810 RepID=A0A1H3XNM4_9MYCO +------SFEELEDRYQAIIGVYAVDLESSATV-EHRPDERFAICSTFKAYAAARILQMAK +AGQANLDAMVPITTADIVVNSPVLGPAVGARMPLRDICAAALTQSDNAAGNIMLRTIGGP +SALTDFARSIGDSQTRLDRWEPDLNEAAPGDLRDTTTPRALCGGYRAILVGDALPGAAQF +QLQRWMGETATSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGMLIGPKRERVMLTVLIRT +RTRDAGPFNEAVAECVRSVL--- +>[subseq from] Beta-lactamase n=2 Tax=Mycobacteriaceae TaxID=1762 RepID=A0A0E3TTK1_MYCCH +--------TALEDWYKARIGLYAIDLNSLTTI-EHRADDQFSMCSTFKTYAAARLLQLAD +AGAIDLNTKVAIASDEIVVDSPITRGEAGSSMSLGDICAAALIHSDNTAGNIMLRTIGGP +TAITAFAQSIGDSHSRLDRWEPDLNTAVPADPRDTTTPRALCTGYRQILTADVLAIQARD +RLLTWMRSNVTSSKRFRAGLPPGWTSADKTGAGDYGSTNDAGLLIGPAGQRVVVAVMTRS +RDQDAPPFNEAIAGAIRV----- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDBAD86 +---VEDRLRELEIRSGGRLGVAVLDTATGRVI-GNRLDERFALCSTFKALAIAFTLARVD +RGEEKLDRRIFFAEKDLVMPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP +SALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIVLGSALSSTSRA +HLTEWMMASRDAAQRLRAGLPVGWRIANKPGTWEGIATNDIGVIFPPNRPPIVVAAYLGR +ARGSVADQEAVLAEVARIIT--- +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas koreensis TaxID=93064 RepID=A0A430G551_9SPHN +---WKSGMDRLREETGARIGLAVYDSGTGRRY-FDGAEARFAMCSTFKVPLAAAVLARAD +RGEIDLTRELRFSEADLLDYAPVVKANLAKGMSIEALLEAAVVMSDNAAANLVFGQISGP +RGLTAFIRSAGDTLTRSDRDEPTLNNVRNGEVRDTTTPQAMLWLLNALLLGETLAPASRA +KLIGWMEASPTGKDRLRAGLPKTWRVGDKTGTSGEGYVHDVAIATPPGRKPLLITCYMDA +PMLPAAKANAAHAKVGELV---- +>[subseq from] Beta-lactamase n=1 Tax=Gluconobacter japonicus TaxID=376620 RepID=A0A149TNM6_GLUJA +--------SSYEEATGGHIGVFARNLATGQRL-TWRENERFVMCSTFKASLAALTLLRVD +QGKESLETVVPYTASDLGDYAPVAKANVAAGLSVRAMCQAAVEWSDNVCANLLLVRVGGP +AALTRFWRSLGDRQTRLDDWEPVLNRTPQGGLRNTTTPEAMAWILEHLVFGHALSGASCS +LLTGWMKNCQTGRGRLRAGFPPTWDVGDKTGNNGKDAAGDIAVAWPTREAPLIVCAYTRG +GQPNEKQFFEVFSEIGRIAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Acetobacter senegalensis TaxID=446692 RepID=UPI00128DB341 +-------ISQHENETGGHVGFYAENTQTGATL-GWRTDERFVMCSTFKASLAACVLARVD +KGLDTLERPLSYTAADIADYAPVAKANLAKGMTIRELCAGAVEQSDNTCANLLLAHIGGP +SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGPVLSAPSRI +ILTDWLIRCRTGEHRLRAGLPSAWKIGDKTGNNGKDAAGDIAVIWPHPETSIVVCAYTRG +GHPTEQQLSSVFAGIGKLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. OK889 TaxID=2135745 RepID=A0A4R7AAR7_9MYCO +------KFEELEDRYQALIGVYAVDLESLATV-EHRADERFSICSTFKAYAAARILQMAN +ANQANLDAMVPITAADIVANSPVLSPAVGARMELREICAAALTQSDNAAGNIMLRTIGGP +SAVTDFARSIGDSQTRLDRWEPDLNDAAPGDLRDTTTPKALCGGYRAILMGDALSGAGQF +QLKRWMTETTTSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGLLIGPKRERVMLTVLMRT +RTRDAGPFNEAVAESVRSV---- +>[subseq from] Beta-lactamase n=1 Tax=Listeria grandensis FSL F6-0971 TaxID=1265819 RepID=W7BK79_9LIST +--EANAELKKLEKKYDATLGVYGVNLEDNQKI-SYNEQERFAYVSTYKAIAGGLLLKNLT +--AEQLNKRVYFSKEDLVDYSPVTEKHVESGMTVKEIINAAMTYSDNTAGNILFHQLNGP +KGYQKELAKIGDKTTQADRFEPELNEAVPGDKRDTTTPEAMVKVLSFLVTKGNMASDRLD +YFKQTLIDNTTGDKLIRAGVPEGYAVGDKTGAGSYGTRNDIAVIYPKEKRPLVWIIYSKK +AGKDDEYNDQLIADAAKVLSNYf +>[subseq from] IBC-1 beta lactamase n=7 Tax=Gammaproteobacteria TaxID=1236 RepID=Q83ZP8_ECOLX +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=2 Tax=Ralstonia TaxID=48736 RepID=A0A0J9DYL1_9RALS +----LQAAKSEEAGLKARIGIAVIDKESGYTW-SYRGDEAFPINSTHKAYLCAALLEKVD +QRKLALSDITAISKSDLVTYSPITEKLQS--ATNAQLCEAAVSYSDNTAANKVLENIGGT +QGFNAFMRSIGDHKTRLDRNEPELNEGTPGDRRDTTTPIAAANSLNQIFFSDGLSRNAKA +ELTHWMVNDKVANDLLRKSLPPTWRIADKTGAGGYGSRSIVAVVYPEGKKPLLVSIYITN +TKATLGESNAAIARMGAVLFK-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Leaf226 TaxID=1735691 RepID=A0A0Q4I0X3_9SPHN +-------VAAYEAASGGHVGLYARNLMTGRAI-AWRADERFVMCSTFKASLAACVLNRVD +RGRARLADRIALSPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLQRIGGP +AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMASTIGRLTRGPVLSPSSRA +LLMLWLRQCRTGDARLRAGLPRAWVIGNKTGNNGKDAAGDIGLLWRDPDTPIIISVYTRG +GSPTEAQFKSLFSEVARGVA--- +>[subseq from] Class A beta-lactamase GES-33 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A1V0FXI3_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGACANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. UNC280MFTsu5.1 TaxID=1449048 RepID=UPI0005BBED4B +------RFEELEDRYQALIGVYAVDLESLATV-EHRADERFSICSTFKAYAAARILQMDK +AGQANLDAMVPITAADIVVNSPVLSPAVGTRMELREICAAALTQSDNAAGNIMLRTIGGP +SALTAFARSIGDSQTRLDRWEPDLNDAAPGDLRDTTTPRALCGGYRAILVGDALPGAGQF +QLKRWMTETTTSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGLLIGPKRERVMLTVLIRT +RTRDAGPFNEAVAESVRSV---- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. Leaf226 TaxID=1735691 RepID=UPI000AEFF189 +-------VAAYEAASGGHVGLYARNLMTGRAI-AWRADERFVMCSTFKASLAACVLNRVD +RGRARLADRIALSPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLQRIGGP +AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMASTIGRLTRGPVLSPSSRA +LLMLWLRQCRTGDARLRAGLPRAWVIGNKTGNNGKDAAGDIGLLWRDPDTPIIISVYTRG +GSPTEAQFKSLFSEVARGVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 15-649-1-2 TaxID=2023141 RepID=UPI000B9C0482 +---AEKQFAALEQRFDARLGVFAVDLGSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD +AGTLSLTDTRIVEAEDKVPESAIDW-EAGQVVTLEQLCVAALTRSDNTAGNLLIDAVGGT +GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRFLLTDGPLSNSSRA +TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLGPDGRRILLVVLSRT +ANPDAAAMNELVADAVREIV--- +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas koreensis TaxID=93064 RepID=A0A430CXP1_9SPHN +---WKSGMDQLREETGARIGLAVYDSGTGRRY-FDGAEARFAMCSTFKVPLAAAVLARAD +RGEIDLTRELRFSEADLLDYAPVVKANLAKGMSIEALLEAAVVMSDNAAANLVFGQISGP +RGLTAFIRSAGDTLTRSDRDEPTLNNVRNGEVRDTTTPQAMLWLLNALLLGETLAPASRT +KLIGWMEASPTGKDRLRAGLPKTWRVGDKTGTSGEGYVHDVAIATPPGRKPLLITCYMDA +PMLPAAKANAAHAKVGELV---- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=A0A2N7IDT3_9VIBR +-----KSIEKIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYNFE +NEGLDLGLKVDIESDDLIVWSPVTKHLIGKDLSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLTGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE +TEFTIQERDKVINEIGQLIFDAy +>[subseq from] Class A extended-spectrum beta-lactamase GES-38 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A346MLH2_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGAQNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Frigoribacterium sp. PhB107 TaxID=2485172 RepID=A0A3N1KC12_9MICO +--DVADDLAALEAEFDARVGVSVVDTETGTTA-SHRADERFGYASSIKALAAAQLLHDVP +--AEQRDEVVTWTAADVEAYSPVTSEHVADGLTLAQLAEAAVRKSDNTALNIVLDRVGGP +AGLDQGLEDIGDTTTEVVNREPELNTIEPGSSDDTSTPAAFTADLGALLDSRWLDAPDRA +LLLDWMSGNATGDTLIRAGAPDGWDVADKSGGAG-GIRNDVAVVTPPGRAPVVVTVFTTR +NDPDARYDDALVARAAAIVL--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium sp. CH28 TaxID=2512237 RepID=A0A4Z0N4Z5_9MYCO +---LADRIAALERRHNAFVGLYGVNLASGVTV-AHRDSDPFAMCSTFKAYLSARVLQQAQ +SGQLRLSDTVVVDPDLLRANSPRTEPNVGKPMALADLCAAALQVSDNTAANLLLRVIGGP +PAITAFARSIGDDRTRLDRWETELNSAIPGDPRDTSTPRALGGGIRSVLTTDVLDEPHRR +QLEDWMRANTT--SSMRAGLQPGWSTADKTGSGAYASTNDVGIAFGPNGERVLVAIMTRT +RSNDAPALRDLVAEVTTS----- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Aeromicrobium sp. IC_218 TaxID=2545468 RepID=A0A4R1ADT7_9ACTN +-----DALRGLERRHDARLGLVAVDTGSGAVV-AHRADERFAHASTSKLLLAAAVLERRG +--VDGMQERVRVPT-ATVPHSPATQSRAGGTMTWSEVLDAALRLSDNTAANLLAEDVGGP +SGVTGVLRGWGDDVTRVDRLEPDLNTAEPGDERDTSTPRALAEHVRALVLGDRLPTDARD +RLVDRMRASTTGADLVRAGVPDGWTVADRSGGAAYGSRHDLAVVWPPEGAPIVLAVMTSR +DAEDAQGRDALVAEATRTAVD-- +>[subseq from] Class A beta-lactamase GES-27 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0S2EAE6_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEQEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=2 Tax=Vibrio TaxID=662 RepID=A0A2G1AT19_VIBSP +-----KSIEKIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE +NEGLDLGLKVDIESDDLIVWSPVTKHLVGKDLSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVFGNTLSQESKV +KLKNWMMGNKISDGILRSILPNDWSIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TKLTIPERDTVINEIGELIFDEy +>[subseq from] Class A beta-lactamase GES-31 n=2 Tax=Aeromonas caviae TaxID=648 RepID=A0A165EZV3_AERCA +---FKTDLEKLEREKAAEIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Shimia haliotis TaxID=1280847 RepID=A0A1I4F4N2_9RHOB +-----AAVRDIERDLDARVGFYMHDTHSGQTL-AYAADDRFPLNSTFKLLACGALLGRAE +SGEVSLSQKVRLQDIEIVAYSPEIERRALTGVSLGAACEMTLAVSDNSAANIVLSAIGGP +DGLTGFLRSIGDQVTRLDRWETELNAAVPGDPRDSTSPRAIAFSVERLLLGDALTPASKA +ILREWLAGHRVADALFRAALPSSWEIEDRTGAGGYGSRSIVAVLYPPERAPIVVALFVTE +TEADFDRRNAAAAQIGAAIVAH- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00136968ED +-----------------------------------------------------AVLKRSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDDTFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] class A beta-lactamase n=1 Tax=Raoultella sp. 18102 TaxID=2681434 RepID=UPI00135C8FDC +--SVNAPFAELERRSGGRLGVFAHDLATGRHL-VHRPSERFLMCSTFKLLAVSAVLTRVD +KGSERLDRRIHFGREALLSHAPVTSLHADGEMTIGQLCDAAITVSDNTAGNLLLQAIGGP +DGFNYTMRAFGDTVTRLDRTEPTLNVA--SGVLDTTTPAAMGQVVGRLLSGRLLMPASVA +KLSDWLRGAKPGLTMLRAGLPADADVGDKAGRGTDGQNNDVAVVWKQGKKLLLVAAYYVN +SDMDDTQRNAVLAEVGRVVT--- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL21I4N1 TaxID=1938801 RepID=A0A2S8S1L8_9BURK +----ESPIAGIERRYGGRLGLFAVDTGSGRTL-AYRADERFLMCSTFKGLLVAQVLARVD +AGKEKLERLVHYTERDLIFTSPITKANVAQGMSVGALCQAAVEVSDNTAAILLMRSTGGP +AALTRFMRDLGDTVTRSDRYEPESNQY--SGLLDTTTPRAIATSAARILLGDVLSHQSRR +QLEEWMVACKPGLNRLRAALPADWLAGDRPGTSVERETNDYAIVRPPGRSPLLVAAYYDA +PGVSMELRETVLREAGHVFV--- +>[subseq from] Class A beta-lactamase GES-29 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0S1Z1Y3_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEAEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura oligospora TaxID=111804 RepID=UPI00047BFD7E +--DVQQQLRKLETSYDGRIGAYAIDTGTGKTV-GYRTHERMPSNSTFKAILCGAVLNKAR +TDPGLMNRTFHWTKADVVEASPVTEKNIKNGLTAAQLCEATITTSDNTAANVLLKQVGGP +AAMTRYYRSLGDPTGRLDRYETELNIWSPGEKRDTIMPAFMARDLQRLTVGNSLAPEDRQ +QLITWMKATVTGDARIRAGVPKGWTVGDKTGTSNYAAADDIAIAYPPSGAPVIIAVYTHR +NVKGTPIDNRILAQTTTILL--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000F5F28C9 +--AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST +LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT +QLTKWMLGNTRGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAMLWPTARAPLVMAVSFTQ +PDAGAAPHADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio wodanis TaxID=80852 RepID=UPI00076A4F47 +--SLTENIEAIELSSSGTIGISVLNTATNTTW-NYKGDQRFPMMSTFKTLLCAQMLYNSS +DGILDKQAQTRITQEALIPWSPITEKQIGETITTEKACEATMLMSDNTAANIVLAEIGTP +SSLTLFLRFIGDNTTRLDRIEPALNEAKSDDIRDTTTPNAMTNTLNELLFGQTLNAKDKR +TLKAWMVNNKVSDPLLRSILPQQWFIADRSGAGGFGSRGITAIVWSEQRSPIIIAIYLKQ +TDLNIAERNQVIVEVGNAIFKEf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonadales bacterium 32-65-25 TaxID=1970594 RepID=A0A258J683_9SPHN +---LRRAITAIERSAGGPIGISLLDTHTGERF-GHRANDRFPLCSTFKLLLAARLLHGAD +KGQWAMIERLPVTKADMLFNAPFTEKRIGGSASLLELAEAMAVVSDNPAANIGLARVGGP +AALTRWLRAIGDQTTRLDRNEPEMNNETPGDPRDTTTPTAMLATSRALVEGRILSPAARK +TLYGWMQASKTADTMIRAALPPGWQEANKTGAGSWHARNIVSVITPPGRKPIWVAAYLFA +AKSELAERNRQFVPLGRAIVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075B8C40 +--AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST +LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT +QLTTWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ +PDAGAAPHADVVASAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI000A3D5AD7 +--AADAAFAALEERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--VDGMERAVPIEAADILEYAPVTETRVGGTMTLRELADAAMTRSDNTAAHLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAAYLRAYALGDPLDDDERA +LFTGWLKATQTGATLVRAELPADWTVGDKSGLGAYASRGDIAVIWRSDAAPIVIAVHSAK +DQQDADADDALISGAAKAAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Thalassobius sp. I31.1 TaxID=2109912 RepID=UPI0013005318 +-----DAIRSIERDLGARVGFYMHDTQTGEVI-AYAEDDRFPLNSTFKLLACGALLNRVD +NREANLTDKVRLRDFEFVDYSPALEAHSRAGVSLGTACGMMLSVSDNTAANIVLSAIGGP +EGLTDYLRSIGDQVTRLDRWETELNMAVPGDPRDTTTPRAIAQSAQDLILGDALEPASQA +TLRAWLADHRVADALFRAALPPSWSIDDRTGAGGFGSRSIVAVIYPPNREPIIASLFMTQ +TNADFDSRNTAAARVGAALVEH- +>[subseq from] class A beta-lactamase n=1 Tax=Shinella sp. UYSO24 TaxID=992418 RepID=UPI0011A142CC +---VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD +RGEEKLDRRVFFGEKDLVMPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP +SALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIVLGSALSPTSRA +HLTEWMMASRDAAQRLRAGLPVGWRIANKPGTWEGIATNDIGVIFPPNRPPIVVAAYLGR +ARGSVADQEAVLAEVARIIT--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium aromaticivorans JS19b1 = JCM 16368 TaxID=1440774 RepID=A0A064CDZ8_9MYCO +---VEQRIAALENRHNAFVGLYAQNLNSKVEL-ANRDGDPFAMCSTFKVYLSTRVLQKAQ +AGELRLTDTVVVDPAELKPNSPRTEPNAGQPMAISDLCAAALQVSDNTAANMLLRVIGGP +PAITAFARSIGDDRSRLDRWETELNSAVPGDPRDTSTPRALGGGFARVLTGDVLDGSHRT +QLEDWMRANTT--SSMRGGLPAGWTTADKTGSGDYASTNDVGIAFGPNGERVLLAIMTRT +RSDDAEPLRQLIAEVATLVL--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T4E9_9BACT +-eALSETVARIEEQLGARVGLSLMETGTGWSW-SHREDELFLMNSTVKVPVCGAILARWD +AGRLSLSDALPVRKADLVPYAPVTETRVGGNMTLDELCLAAIDMSDNVAANILIGHLGGP +EAVTQLFRSVGDPTSRLDRIEPKLNDFASGDERDTTSPAAMSETLRALLLGDVLSPEARG +KLAEWMRHGGVTGALLRAEAEDAWLILDKSGSGSH-TRNLVAVIQPEGGAPWIATMFISD +TDAEFEVRNEALKDLGRAVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C847E11 +-----QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE +NEGLNLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPDDVRDTTTPNSMVVTLNELVYGNTLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWIIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE +TEFTIQERDKVINEIGQLIFDAy +>[subseq from] Beta-lactamase n=1 Tax=Clavibacter sp. 199 TaxID=2183923 RepID=A0A3D9PSZ0_9MICO +--AADAAFAALEERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLVAALLDRVG +--IAGMGRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAAYLRAYALGDPLDADERA +LFTGWLQATRTGATLVRAELPTDWTVGDKSGLGAYASRGDIAVIRRPDAAPIVIAIHSSK +DRQDADADDALISGAAKAAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Tokpelaia sp. TaxID=2233777 RepID=A0A5M8P9U6_9RHIZ +------AIAGSEEKFQARIGIAVLDKAGGIIA-AWRAYEHFPLNSTYKPLLCAALLHKVD +KGALDLSDKVRFDKSRLVSYSPVTQNFITPAMDWRQLCRAAVEFSDNTAANLILAALGGP +GEFNRFLRNMGDNITQLDHFEPDLNHIKPGDKRDSTMPVAIGRTLQQLVFGDILQPQSRR +QLTQWLLNDKVADELLRSVLPPQWKIADKTGAGDYGSRSIISIIWPQKREPLLIAIYITA +TKASIAQTNAAIARIGKKIF--- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. ATCC 55076 TaxID=1909395 RepID=A0A1U9ZY68_9ACTN +---VEEELRALEVAFEGRIGAYAVDTGTGRSV-AYRAGERFPLLSTFKAPLCAAVLCRAR +RERGLMGRRLRWRACDMTPNSPVTGRHLEGGLTVAELCAAAVTRSDGTASNLLMELIGGP +RGMTAFFRGLGDAVSRVDRWHPGLNEWVPGDERDTTTPAAMAGVLRALAVGGALHPEDRQ +RLVGWLLASQVGAGRVPAGLPAGWTVGHKTGTNSFGGGHDVAVVWTEAGAPIVMAVYTNR +TP-GLPTDDSVLARTAKVLVR-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium chlorophenolicum L-1 TaxID=690566 RepID=F6EYG4_SPHCR +--------KEIESESGGRLGVALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAVLSGAE +GNKFGLEGQIGFTKADLLDHAPVVKKNARRGMSMEELAAAAVEVSDNSAANLLLPMIGGP +EGFTRYVRAHGDNVTRLDRTEPALNENAEGDERDTTSPAAMAGLMRRLIFTD-LKPESAA +RLRGWLNASTTGGNRIKAGLPKDWTSGSKTGTCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDAKAAEAAIAETARAALD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=A0A107TAU6_9BURK +--AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST +LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT +QLTTWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ +PDAGAAPHADVVAAAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Selenomonas sp. mPRGC5 TaxID=2593411 RepID=A0A5D6VZU9_9FIRM +------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTHKVFTAAELLRQKN +--TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASIRWSDNTAANLILQEIGGV +ENFKVALKNIGDKTTKPARNEPELNLFDPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK +LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRNPIVMAIMSRR +TEKNAKFDDAMIAEAAKRIFD-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. (strain SKA58) TaxID=314266 RepID=Q1NAL0_SPHSS +--------KEIEEETGGRLGVALVDRQGALLL-GFNRDERFAMCSTFKAPLAAAVLTGAD +GGKFGLEGTIPFGKEDVLDYAPVVKKNLKRGMSMEELARAAVEVSDNSAANLLLPMLGGP +EGLTAFMRVHGDDVTRLDRTEPALNENAEGDPRDTTTPAAMAGLMARLFFRD-LKAESAD +RLRAWFNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPTGEEYILAIYLDR +PTIDAKKAEAAIAEAARAALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075BED39 +--AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST +LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT +QLTTWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ +PDAGAAPHADVVAAAARIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia agricolaris TaxID=2152888 RepID=UPI0012917F40 +-----VSLADVERRHGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLARVD +AGKDDPGRLVRYTEKDLVFTSPVTKAHVAEGMPVGALCQAIVEVSDNTAAVLLMRSAGGP +AGLTQFVRGLGDTVTRSDRYEPESNRY--SGVLDTTTPRSITNSASKILLGNVLSPQSRT +QLEKWMTACKPGLNRLRAALPPDWVAADRPGTSVEEQTNDYAIVRPPGRAPLLIAAYYDA +PALGMPAREAVLREVGAVFV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas adhaesiva TaxID=28212 RepID=A0A2A4IAQ1_9SPHN +-----DPIAAYERATGGRIGVYARNVRTGKTL-SWRADERFIMCSSYKASLAAFVLARVD +RGEERLDALVAYSARDTVDWGPVAKENLARGMSVEAMCKAAVEISDGVCANMLMARSGGP +AALTAFLRSIGDATTRVDHYEPALDRVPSGGPDDSTTPAAMAATLEKVVLGDVLSDRSSA +LLTRWLVGNQT-NPRLRGGLPKDWRIGNKTGHSGRDMAGDIAVAWPTPDTPIVIAVYTRG +GTPREKQFDRAFAGIGRMIA--- +>[subseq from] Beta-lactamase n=1 Tax=Legionella adelaidensis TaxID=45056 RepID=A0A0W0R1T6_9GAMM +-dELLKSIEKIENSTNARIGFFAINTANNTTL-HYRADERFPMGCTSKVIGVAAVLHKSM +HDENLLSKSIHYTKDDLTNWTPITEKNVNAGMSIQALCAAAISYSDNTAMNLLVKQLGGL +DEINGFARTLHNDSFRQDHNWPEEALSGGKDISDSSTPRDMARSVQRLVIGNHLNNYQKD +LLIQWLKANTTGDQKIRAGVPKDWVVGDKTGTGSYGTTNDIAVIWPPHCQPIVLAIYYTN +KNKKAPIRNDIVASVTKMVIQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea indica TaxID=1581193 RepID=UPI000C7A5604 +--DIRAEFRKLETAYQGHIGAYAIDTGTGRTV-GNRAHERFPSNSTFKAILCGAILHKAR +TDPGLMERTLKWKATDVVAHSPVTKENIENGLTPERLCHATITTSDNTAANVLLKQIGGP +AGMTRYYRSLGDPVGRLDRYETELNDWKPGERRDTIMPAFMARDLQKLTVGKALVPEDRS +RLIGWMKDSTTGRERILAGLPKGWTVGDKTGTGGYGTASDLAIAWPPSGAPVIIAVYVRR +GVADAQVDNGTIAKATSLLV--- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8MRI6_9BACI +----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS +--LEALDQRITYTHEDLSNYNPITEKHVNTGMTLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAII---------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=UPI000D17CDCA +--NIDSAIKQAEQQLGAKVGVSVLNANGDSLY-GYNSDQRFPLMSTFKTLACAKLLHDNQ +ITQGMMDKTYPVTAEAILDYAPVFKDKVGTEVSLKDACFATMTTSDNSAANFVLAHIGGA +EGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA +QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG +TEASIPERDKEIAKIGNAIFERy +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium sp. GB-1 TaxID=2022111 RepID=A0A2T3LNL5_9GAMM +---VNSAIEHAEKQLGARIGVSVVDGKGKQLF-GYNSDQRFPLMSTFKTLACAKLLHDNQ +INDGMMDKTYLINADTILDYAPVFQDKVGTEVSLKDACFATMTTSDNSAANLVLSHIGGP +VGVTTFLIDSGDNVTRLDRIEPLLNEATPGDERDTTTPYAMNKTISNLVLGNALNASSKQ +QLKDWMKANKVSNGLLRSVLPKGWEIADRSGAGGHGSRGITAVVWNEQKQPLVISIYLTG +TKASIPERDKEIAQIGQAILQHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4P8JGN2_ECOLX +--------------------------------------------------AAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAG------- +>[subseq from] class A beta-lactamase n=1 Tax=Acetobacter pasteurianus TaxID=438 RepID=UPI000553618C +---------SYENATDGHIGVFAQNLATGQRL-TWRENERFVMCSTFKASLAALTLLRVD +QGKESLETFVPYTASDLGDYAPIAKANVGAGLSVRAMCEGAVEWSDNVCANLLLARVGGP +AALTRFWRSLGDHETRLDDWEPALNRTPPGGRRNTTTPAAMAGILRQLVFGHVLSETSCS +LLTGWLKNCHTGGSRLRAGFPSTWAAGDKTGNNGKDAAGDIAVAWPKPEAPLIVCAYTRG +GHPDEKQFFEVFSEIGRIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=A0A2T3QBD0_PHOAN +---VNSAIEHAEKQLGARIGVSVFDSKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ +INNGMMDKTYQITADAILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP +VGVTTFLIDSGDSVTRLDRIEPLLNEATPGDKRDTTTPYAMNKTITNLVLGNVLNESSKQ +QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG +TKASIPERDEEIAQIAQAILQQf +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. BL21I4N1 TaxID=1938801 RepID=UPI000CFCA5B7 +----ESPIAGIERRYGGRLGLFAVDTGSGRTL-AYRADERFLMCSTFKGLLVAQVLARVD +AGKEKLERLVHYTERDLIFTSPITKANVAQGMSVGALCQAAVEVSDNTAAILLMRSTGGP +AALTRFMRDLGDTVTRSDRYEPESNQY--SGLLDTTTPRAIATSAARILLGDVLSHQSRR +QLEEWMVACKPGLNRLRAALPADWLAGDRPGTSVERETNDYAIVRPPGRSPLLVAAYYDA +PGVSMELRETVLREAGHVFV--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia ammonioxydans TaxID=260086 RepID=A0A1I5FJ77_9PSEU +-------LSDVEREFGRRIGVHASDTGSGAAV-AHRGDERFLLCSTVKALMAGFVLHRSV +TDPALLDRVVRWDRSEVLEYAPVTARHVDTGLTVAQLCEAAVTVSDNTAHNVLLREVGPP +AELTAWLRTTGDTVTRADRAEPALNEA--DGDRDTSTPAAFSATLAGLTTGAALPPAQRD +RLVGWLRAATTGSRQIRAAAPAGWQIGDKTGSGPGGEKNDAAILFPPDGAPIALTVFTVA +TDPDDDRGEEAIAAATRAAL--- +>[subseq from] Extended-spectrum beta-lactamase GES-15 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=D2KFE7_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKESEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Class A beta-lactamase GES-43 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A5B8KSP3_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKESEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase IBC-2 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q9AGN8_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQLAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Class A beta-lactamase n=1 Tax=Lentzea guizhouensis TaxID=1586287 RepID=A0A1B2HPC8_9PSEU +----HDQLFALEQKFGARLGVFAGR--GDRTV-EHRADERFAFCSTFKGLVTAAVLDRDV +----PLDTVVRYTDADLMKSSQITRQHVATGMSLRDLCDAAVRYSDGTAGNLLLRTIGGP +AELTTYLRGLGDEVTRMDRWEPDLTSAVPDDPRDTSTPRALGTTYRKLVAE-------KQ +FLRDLMERNTTGGQRIRAGVPKDWKVADKTGTGDYGTMNDVGLAWPPAGEPLLISLMSSK +PTADAPYDQALLAEAAAYVIT-- +>[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A251YH76_9MICO +--AADAAFAALEERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--VDGMERAVPIEAADILEYAPVTETRVGGTMTLRELADAAMTRSDNTAAHLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAAYLRAYALGDPLDDDERA +LFTGWLKATQTGATLVRAELPADWTVGDKSGLGAYASRGDIAVIWRSDAAPIVIAVHSAK +DQQDADADDALISGAAKAAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000758367C +--AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST +LDASLLSRRTLYRRYELVPGSPVTDSRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT +QLTKWMLGNTRGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTARAPLVMAVSFTQ +PDAGAAPHADVVAAAARIAA--- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1P456_9ZZZZ +--ETLVKVKDAEDQLGARVGYIQLDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGW------------------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea indica TaxID=1581193 RepID=UPI000C7AD9C7 +--QARKELRALEASFQGRIGAYALDTATGKTI-TYRAGERFPLLSTFKAPLCAAVLHKAR +TAPGLMGKHVTWTADDLTPGSPVTEKHVATGLTVAQLCAAATSVSDGTASNLLLREIGGP +AGLTRYFRTLKDPISRMDRFHPALNDWTPKDRRDTTTPAAIARDLRLLALGNALHPEDRE +QFVAWLLANRTGANRIRAGLPRTWTIGDRTGTNSFGGGNAIAVIWPDKGAPLVMAIYTNR +TP-GLPIDEKTIARTATILAD-- +>[subseq from] Beta-lactamase n=1 Tax=Hyphomonadaceae bacterium TaxID=2026748 RepID=A0A2E4S1Y6_9RHOB +-------IEALELGHEGRFGGAAVTSGGEDLV-SHRADERFAMCSTFKWLMAGLVLQEVD +SGRETLERRVPIAGEDLVFHSPVTSQHVGAQLPVSQLCAATIGTSDNTAANLLLAGLGGP +DGFTQRLRASGDMVTRLDRMEPALNENEPGDPRDTTTPRAMARNLDRFLFGSQLSAPSRD +MLRTWMIAADTGLDRLRAGLPAGWTSGDKTGTSSNGANNDVAFSIPPDAKPLIIASYLNL +PDPVSPEANALHAKIAGLV---- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium gallinarum TaxID=39689 RepID=UPI0013D4EB17 +--SIEASLQGLEQRHNAVIGLFASNLVSDKTV-AHRAQDPLALCSVFKGYASARVLQMAQ +HGELSLDEGMFVDPAQILPNSPVTGPRAGSEMTLAELCQATLQQSDNAAANLLLSRIGGP +QAITAFARSIGDGQTRLDRWETELNSAIPGDPRDTSTPEALGGGYRALLDGDVLAPPQRG +LLEDWMRANQT--SSMRAGLPPAWTSADKTGSGSYGTTNDVGIAYGPEGQRVLLAIMTRS +QANDAANMRPLIGEITALVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio tasmaniensis TaxID=212663 RepID=UPI0007EEF3F5 +-----QSIEQIESRISARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE +NEGLNLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISFSLTE +TEFTIQERDKVINEIGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderiales bacterium C2 TaxID=2502236 RepID=UPI0010F79A86 +-----APFATLEQKAGGRLGVAVLDCADGALI-GHRWQERFALCSTFKLPLAGVVLREAD +QGRLQLDRPLRYGLADMVPHAPVTGRHLASGMSIAALAEATQTTSDNVAANLLLRELGGP +AGLTARLRELGDGETRLDRYEPQMNVVHAGELRDTSTPLAMARTTDRLLNSDWLAPASRE +RLAQWMIATDTGLKRLRAGFPAGWKAGDKTGTFMDDKYNDVAIAWPPGRPPLIVSAYYEG +PGRHRDQDQAVLAEVGRLAAAW- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus sp. EPR-157 TaxID=1813677 RepID=A0A164PHL6_9NOCA +--TIDDDVAALEQRHGAQIGLWASDLTSGATA-SYRPRESFAMCSTFKPYAVAVALQFAS +RGLLNLDDAVPVTASDIVVNSPVLSTLIGGSITLSQACDAALTRSDNAAGNIVLRAIGGP +PAITAFARSVGDARSQLDRWEPELNEALPGDPRDTTTPESLAAGYRAILTGDALEKPHRE +RLVGWMRDTRTSDERFRAGLPLGWSSADKTGAGYYGSTNDAGLLFGPSGQQILVVVLTRS +HNQDASPLNEAIADTVRVTLSNf +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium sp. SKA34 TaxID=121723 RepID=Q2C377_9GAMM +---VNSAIEHAEKQLGARIGVSVLDGKGKQLY-GYHSDQRFPLMSTFKTLACAKLLHDNQ +INNGMMDKPYQITADAILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP +VGVTTFLINSGDSVTRLDRIEPLLNEATPGDKRDTTTPYAMNKTITNLVLGNALNKSSKQ +QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGHGSRGITAVVWNEQKQPLVISIYLTG +TKASIPERDKEIAQIGQAILQQf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. S1 TaxID=1641859 RepID=UPI00131BCAC2 +------PLADIERRNGGRLGVFAIDTGSGRTS-AHRADERFLMCSTFKGLLAAQVLSRVD +AGKEDPARLVRYTEKDLVFTSPVTKAHVAQGMSVGALCQAIVEVSDNTAAVLLMRGAGGP +AGLTQFVRSLGDTVTRSDRYEPESNKY--SGVLDTTTPRSITKSASQILLGNVLSPQSRA +QLENWMIACTPGLNRLRAALPPDWIAGDRPGTSVEEETNDYAIVRPPGRAPLLIAAYYDA +PALAMAAREAVLREVGAAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MJM1172 TaxID=1703926 RepID=A0A1Q5AWM8_9ACTN +---LAGALGELEREHSARLGVFARNTATGRTV-AYRADERFPVCSVFKTLAAAAVLRDLD +RDGEFLARRIRYTAEEAEKYAVVTGRNVANGMTVEALCAAAVSESDNMAANLLLRELGGP +RAITRFSRSLGDRITGLERWEPELNSAEPWRTTDTTSPRAIGTSYGHLLLGDALDPRDRE +RLTGWLLANTTNGERFRAGLGPDWILADKTGGGNYGVTNDVGVVRAPDGPPIVMAVLSTK +PGPEGPRDNPLVAKTAALLAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BD0F45 +-----SPLAEIERRNGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTENDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAMAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9125 TaxID=2184569 RepID=A0A3N8CGV6_9BURK +---AQSQLDALEKASNGRLGIAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST +LDTSLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QTVTAFARGSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT +QLTKWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ +PDAGAAPHADVVAAAARIAA--- +>[subseq from] Uncharacterized protein n=1 Tax=Sphingomonas sanxanigenens DSM 19645 = NX02 TaxID=1123269 RepID=W0AC30_9SPHN +--AVADPIAEYERATGGRIGVYALNVKTGTEI-AWRADERFIMCSTYKALLASFVLSRVD +RGQEELDSPVPYTAGDTLEWAPVANANLKKGMTVEAMCRAAVEISDGACANLVMARSGGP +SALTAFLRSIGDETTRVDHFEPALDRSPSGGPDDSTTPRAMATTLQALVLGTTLSAGSRA +RLTAWLMGNQT-NHRLRRGLPRRWRIANKTGHSGRDMAGDIAVVWPRPDTPILIAVYTRE +GTPTERQFDRSFGDIGRLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium DSM 44124 TaxID=1226753 RepID=A0A5N5VBM4_9MYCO +------SFEELEDRYQAIIGVYAVDLESSATV-EHRPDERFAICSTFKAYAAARILQIAK +AGQANLDAMVPITTADIVVNSPVLGPAVGARMPLRDICAAALTQSDNAAGNIMLRTIGGP +SALTDFARSIGDSQTRLDRWEPDLNEAAPGDLRDTTTPRALCGGYRAILVGDALPGAAQF +QLQRWMGETATSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGMLIGPKRERVMLTVLIRT +RTRDAGPFNEAVAECVRSVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Listeria booriae TaxID=1552123 RepID=UPI00068BF7B6 +--QAKEALNQLEKKYGSELGVYAVNPENSQTL-QYNAQERFAFVSTYKAIASGVLLKNLT +--EQQLEKRVFFKKEDLVDYSPVTEKHVESGMTIKEIIHAAVAYSDNTAGNLLFNALNGP +KGFQDELRKIKDETTNSDRYETELNTAIPGDSRDTSTPEAFAKNLAFLTKQGNLQPKQLD +YFKQTLIENTTGDKLIRAGVPKGYIVGDKTGAGSYGTRNDIAVIYSDDKEPLVWVIFSKK +DKEDAEYDDQLIADAAKVLSRYf +>[subseq from] Beta-lactamase n=2 Tax=Granulibacter bethesdensis TaxID=364410 RepID=Q0BSY1_GRABC +---VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD +RGEEKLDRRVFFGKKDLVMPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP +SALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIVLGSALSPTSRA +HLTEWMMASRDAAQRLRAGLPAGWRIANKPGTWEGISTNDIGVLFPPNRPPIVVAAYLGE +ARGSVAEQEAVLVDVARIVTR-- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9126 TaxID=2184570 RepID=A0A3N8DN42_9BURK +--AAQSQLDALEKASNGRLGIAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST +LDTSLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP +QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT +QLTKWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ +PDAGAAPHADVVAAAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. Leaf278 TaxID=1736319 RepID=A0A0Q6KQ02_9NOCA +--SAEQAYLELEARDSARLGVSALDLATGSTQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLQLSDTRTIAAEDKVPESAVD-WEPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSLAAGYRTLLDGDVLTQASRA +QLLEWMGDTETSTARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT +TSEDSSAMNPLVADATRTAVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A270L936_ACIBA +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSPSKVMAVAAVLKQSA +PQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDK------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A2A5YW45_9SPHN +--------KEIEEETGGRLGVALVDRRGALLL-GFNRDERFAMCSTFKAPLAAAVLTGAD +GGKFGLEGTIPFGKEDVLDYAPVVKKNLKRGMTMEELARAAVEVSDNSAANLLLPMLGGP +EGLTAFIRVHGDAVTRLDRNEPALNENAEGDPRDTTTPAAMAGLMARLFFQD-LKPDSAD +RLRAWFNASSTGDKRIKAGLPEGWTSGSKTGSCGN-AYNDVALVKSPKGEEYILAIYLDR +PTVDAKKAEAAIAQTARAAL--- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingomonas sp. MEA3-1 TaxID=1647414 RepID=UPI00065CAD1B +--------KEIESATGGRLGVALVDSKGALML-GFNRDERFAMCSTFKAPLAAAVLTGAE +GGKFGLEGQISFTKSDLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP +EGLTRFIRAHGDMVTRLDRNEPSLNENVEGDERDTTSPAAMAGLMGRLIFRDL-APESAE +KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTIDARAAEAAIAETARAALD-- +>[subseq from] Class A beta-lactamase GES n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A110AZV8_PSEAI +---FKTDLEKLECEKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A0C5X7Q2_SPHYB +--------KEIESATGGRLGVALVDSKGALML-GFNRDERFAMCSTFKAPLAAAVLTGAE +GGKFGLEGQISFTKSDLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP +EGLTRFIRAHGDMVTRLDRNEPSLNENVEGDERDTTSPAAMAGLMGRLIFRDL-APESAE +KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTIDARAAEAAIAETARAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinokineospora sp. TRM65233 TaxID=2654637 RepID=UPI0012E99B29 +-------LAELERRFDARLGVHATR--GARVV-EHRADDRFAFCSLFKALATAAVLARHP +--LSHLDDVIRYTRADLLDNARITPANVDSGMSVRALADAAIRHSDGTAGNLLLRDLGGP +AELTAYARELGDTVTRMDRVEPDITEATPGDPRDTTSPRAFGTSFSRVVLGDALPEDKRA +VLVDLLVRNTTGARRTRARVPAGWRIANKTGTGDYATANDVAVLWPPTGDPVTLAIMSSR +ADRTAERDEALVAEAAGLVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C8600E5 +-----QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKSLACANLLYDFE +NEGLDLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVATLNELVYGNTLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE +TKLTIPERDTVTNEIGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Gemmobacter aquaticus TaxID=490185 RepID=UPI0011B46E11 +--ALEQTVSAVEAQLSGRVGIVVGQAGQDALW-SWRGDERFVMTSTFKVPLCGAVLTAAD +QGQLDLAQEIEIKPSDLIPHAPVTEQHLDAPMAIADLCMATIDMSDNTAANLLIKALGGP +EAVTDVFRSLGDSESRLDRYEPELNLAAEGDLRDTTTPLAMAHTLETLLIEDFLSANSRA +LLGEWMGKGGVTATLLRDKLPEGWTVYDKSGGGSD-SRSLIAVASTAGEAPWVISIYLAD +MEHDFATRNSALQSIAAAVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium mucogenicum TaxID=56689 RepID=UPI0006B3316A +------SFEELEDRYQAIIGVYAVDLESSATV-EHRPDERFAICSTFKAYAAARILQIAK +AGQANLDAMVPITTADIVVNSPVLGPAVGARMPLRDICAAALTQSDNAAGNIMLRTIGGP +SALTDFARSIGDSQTRLDRWEPDLNEAAPGDLRDTTTPRALCGGYRAILVGDALPGAAQF +QLQRWMGETATSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGMLIGPKRERVMLTVLIRT +RTRDAGPFNEAVAECVRSVL--- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter tropicalis TaxID=104102 RepID=A0A149U0P8_9PROT +-------ISQYENETGGHVGFYAENTKTGATL-GWRTDERFVMCSTFKASLAACVLARVD +KGLDTLERPLSYTAADIADYAPVAKANLAKGMTIRGLCAGAVEQSDNTCANLLLAHIGGP +SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGSVLSAPSRI +ILTDWLIRCRTGEHRLRAGLPNEWKIGDKTGNNGKDAAGDIAVIWPTPETSIVVCAYTRG +GHPTEQQLSSVFAGIGKLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Leaf30 TaxID=1736213 RepID=A0A0Q4KEB2_9SPHN +-------VADYETASGGHVGLYARNLTTGRAI-AWRADERFVMCSTFKASLAACVLNRVD +RGRARLADRIALSPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLQRIGGP +AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMASTIGRLTRGPVLSPSSRA +LLMLWLRQCRTGAARLRAGLPRGWAIGNKTGNNGKDAAGDIGLLWRDPDTPIIISVYTRG +GSPTEAQFKSLFLEVARGVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. Leaf30 TaxID=1736213 RepID=UPI000A439AC8 +-------VADYETASGGHVGLYARNLTTGRAI-AWRADERFVMCSTFKASLAACVLNRVD +RGRARLADRIALSPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLQRIGGP +AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMASTIGRLTRGPVLSPSSRA +LLMLWLRQCRTGAARLRAGLPRGWAIGNKTGNNGKDAAGDIGLLWRDPDTPIIISVYTRG +GSPTEAQFKSLFLEVARGVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. MJM1172 TaxID=1703926 RepID=UPI0009A16024 +---LAGALGELEREHSARLGVFARNTATGRTV-AYRADERFPVCSVFKTLAAAAVLRDLD +RDGEFLARRIRYTAEEAEKYAVVTGRNVANGMTVEALCAAAVSESDNMAANLLLRELGGP +RAITRFSRSLGDRITGLERWEPELNSAEPWRTTDTTSPRAIGTSYGHLLLGDALDPRDRE +RLTGWLLANTTNGERFRAGLGPDWILADKTGGGNYGVTNDVGVVRAPDGPPIVMAVLSTK +PGPEGPRDNPLVAKTAALLAQ-- +>[subseq from] Class A beta-lactamase n=1 Tax=Mycobacterium sp. ENV421 TaxID=1213407 RepID=A0A2N8LFR6_9MYCO +---VEQRIAALEKRHNAFVGLYAQNLDSTVEL-ANRDGDPFAMCSTFKVYLSTRVLQKAQ +AGELRLTDTVVVDPAELKPNSPRTEPNAGQPMAISDLCAAALQVSDNTAANMLLRIIGGP +PAITAFARSIGDDRSRLDRWETELNSAVPGDPRDTSTPRALGSGFARVLTGDVLDGSRRT +QLEDWMRANTT--SSMRGGLPAGWTTADKTGSGDYASTNDVGIAFGPNGERVLLAIMTRT +RSAQAEPLRQLIAEVATLA---- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium brumae TaxID=85968 RepID=A0A2G5P4C1_9MYCO +-----GRFAELEARHNALIGVYAANLDSGRVI-EERADESFAMCSTFKAYLAGRVLQLVE +RGQLTLEQRIFVDSRSIIMNSPVTKLHSGDFMTVAELCQAILQVSDNAAANLLLARVDGP +AGITAFARSIGDERSRLDRWETDLNAAAPGDPRDTSSPRALAGGFRELLTGEVLSVQRRR +LLEDWMRANQT--SSMRAGLPAGWASADKTGSGDYGSTNDVGIAFGPAGERLLLAILIRS +AGADPK----------------- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. NEAU-G17 TaxID=2293572 RepID=A0A372JVJ5_9ACTN +-------FAALERKYKARLGLFAVATGTGATV-AYRPDERFAFCSTFKPLAAAAVLDRRP +--VSELEKRVRIRAADVNSISPITRKRIGSAMSLRELCDAAIRFSDGTAGNLLVRDIGGP +AALNAYLRRLGDPVTRMDDLEPELNRVGPGDPRDTTTPRAITADYRSLVLGDALPAAKRA +LLAGWLDRSVPGADRIRAALPPEWTIAHKTGTGDYGRAADVAVLRPPQGPPLVLGILSDR +EGYTTPPAGRLLAEAARLVVT-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. AP50 TaxID=1884369 RepID=A0A1H7AH71_9SPHN +--------KTIEEETGGRLGVALVD-KSGALLlGFNRDERFAMCSTFKAPMAAAVLTGAD +AGKFGLSGEIPFGKDDILDYAPVVKKNKKRGMSMGELAQAAVEVSDNSAANLLLPMLGGP +EGLTAFMRAHGDSVTRLDRNEPTLNENAEGDPRDTTTPAAMAGLMGRLFFNDM-KPESAD +KLRAWFNASSTGDNRIKAGLPTGWTSGSKTGTCGT-AYNDVALVKSPTGDEYILAVYLDR +PTVDAKKAEAAIAETAQAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=UPI0003617916 +---VDERLKEIEDRYAVRLGVFAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA +EGSLRLDETLPIDPDDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP +GAVTAFARSVGDETTRLDRWEPELNEAARGDQRDTTTAAGLSRGFGEVLLGSGLPAPQQR +TLLGWMRATTTSDTRIRGGLPSGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium japonicum TaxID=332056 RepID=N1MPK8_9SPHN +--------KTIEEETGGRLGVALVDSKGALIL-GFNRDERFALCSTFKAPLAAAVLIGAE +GGKFGLEGEIPFGKDDILDYAPVVKKNRKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP +QGLTAFMRAHGDSVTRLDRNEPTLNENAPGDPRDTTTPAAMAGLMGRLLFRDM-QGASAD +QLRAWLNASSTGDKRIKAGLPEGWTSGSKTGTCGT-AYNDVALVKAPSGEEYILAIYLDR +PAVDAKAAEAAIAQAAQAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. RB68 TaxID=2585200 RepID=UPI001297AA8B +--EVTRRLRDLETAYKGRIGAFAVDTGTGRVV-GHRAHERFPFLSTFKALAAAAVLHKAR +TDPGLMERVVHWTEQEEKPNSPKTKGQGGPDMTVAQLCDAAIRYSDNTAGNMLLKQLGGP +AGYTRHLRSLGDPVSRLDRWEIELNDWKPGERNDTTTPANMGADLREVTAGGALVPADRA +RLVGWLRANTTGDARIRAGLP-HWTVGDKTGSAD-ARANDVAVAWPPGAAPVIIAVYTYR +HDLTAPREDKVIADTAAVLA--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. YR768 TaxID=1884365 RepID=A0A1H9LMP1_9SPHN +--------KTIEEETGGRLGVALVD-KSGALLlGFNRDERFAMCSTFKAPMAAAVLTGAD +AGKFGLSGEIPFGKDDILDYAPVVKKNKKRGMSMGELAQAAVEVSDNSAANLLLPMLGGP +EGLTAFMRAHGDSVTRLDRNEPTLNENAEGDPRDTTTPAAMAGLMGRLFFNDM-KPESAD +KLRAWFNASSTGDNRIKAGLPTGWTSGSKTGTCGT-AYNDVALVKSPTGDEYILAVYLDR +PTVDAKKAEAAIAETAQAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C823B30 +-----QSIEQIESRISARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYNFE +NEGLNLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISFSLTE +TEFTIQERDKVINEIGQLIFDAy +>[subseq from] Beta-lactamase n=2 Tax=Pseudonocardia sp. AL041005-10 TaxID=445576 RepID=A0A0M3U972_9PSEU +------ALADVEREYARTIGVHVLDTGTGAAA-GHRDGDRFLMCSVVKALMAGFVLHRSL +SEPGLLDRPVRYGRADLLEYAPVTTRNLATGMTVGGLCEAAVTVSDNTAHNLLLREVGSP +AELTAWLRTTGDGVTRADRSETALNDR--DGERDTSTPAALAATLRTLVLGDALPSAQRD +RLTGWLRANTTGDRQIRAAVPAGWTVGDKTGSGPLGERNDAGVLYPPDGAPLVLTVFTVP +ADADRARGEAAVAAAARAAI--- +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=T0H546_9SPHN +--------KEIEEETGGRLGVALVDRQGALLL-GFNRDERFAMCSTFKAPLAAAVLTGAD +GGKFGLEGTIPFGKEDVLDYAPVVKKNLKRGMSMEELARAAVEVSDNSAANLLLPMLGGP +EGLTAFMRVHGDDVTRLDRNEPTLNENAEGDPRDTTTPAAMAGLMARLFFRD-LKAESAD +RLRAWFNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPTGEEYILAIYLDR +PTIDAKKAEAAIAETARAALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5630 TaxID=1463864 RepID=UPI0004CA7964 +----AAEFTALERRYGAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKYG +--LAGMDHVLRYDKKDLVANSPVTEKHVDTGMSRDALCDAAIRYSDNTAANVLLADLGGP +RALGALIRTTGDRVTRVERVEPLLSRWTPGETHDTTTPRQLTTNLRAYTLGDVLAAPERD +RLTGWLRANTTGDKTIRAGVPKGWTVEDKTGTGSHGARGDIAVIRPPGRAPLVLTLLSYR +DARTAEAEDQLLAEATQVVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Schumannella sp. 10F1B-5-1 TaxID=2590780 RepID=A0A506Y8Z9_9MICO +haDIAVDLSALEQQYDARVGVVAIDTGTGRTA-SWHGDDRFAYASTLKALAAGLVLQRE- +-GVAALDDPVAIPAAPLIDYSPVTEQHAGGTMTLGEVAAAAVELSDNTAGNLLFARLGGV +DALQKQLRGLGDRTTQVDRIEPDLNEAAPGDERDTSTPRALASSLRALAVDEPLDSVERA +ALNGWLDGSQTGATLIRAGLPDGWTAGDKSGAAGYGTRNDVAVVHPPSGAPIVIAVLSSR +DAPDAEYDDALVAAAARATLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. AD24 TaxID=1528693 RepID=UPI000B5F568C +---TESPIAEIERRYGGRLGVFAINPATGRTL-AYRADERFLMCSTFKGLLVAQVLARVD +AGKENLERLVRYTERDLIFTSPVTKANVAQGMSVGALCQAAVEVSDNTAAILLMRSAGGP +AALTRFMRGIGDSVTRSDRYEPESNQT--SGVLDTTTPRAIATSAARILLGDVLNPESRR +QLDAWMVACKPGLNRIRASLPADWLAGDRPGTSVERETNDYAIVRPPGRAPLLVAAYYDA +PGVSMELRETVLREAGHR----- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter senegalensis TaxID=446692 RepID=A0A149TXS4_9PROT +-------ISQYENETGGHVGFYAENTKTRATL-GWRTDERFVMCSTFKASLAACVLARVD +KGLDTLERPLSYTAADIGDYAPVAKANLAKGMTIRELCAGAVEQSDNTCANLLLAHIGGP +SALTAFWRHLGDKTTRLDNVEPYLNRTPPGGIQNTTTPRSMAFILQHLVSGPVLSAPFRT +ILTDWLIRCRTGEHRLRAGLPSAWKIGDKTGNNGEDAAGDIAVIWPHPETSIVVCAYTRG +GHPTEQQLSSVFAGIGKLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DCF73FC +---VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD +RGEEKLDRRVFFGEKDLVMPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP +SALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIVLGSALSPTSRA +HLTEWMMASRDAAQRLRAGLPAGWRIANKPGTWEGISTNDIGVLFPPNRPPIVVAAYLGK +ARGSVAEQEAVLVDVARIVTR-- +>[subseq from] class A beta-lactamase n=2 Tax=Paraburkholderia bannensis TaxID=765414 RepID=UPI00047F899C +--QTASPLADIERRNSGRLGFYAIDTGSGRTL-EHRADERFLMCSTFKGMLAAQILARID +AGKEQMDRLVHYTGQDLIFTSPVTKANVALGLPVHTLCQAIVEQSDNTAAVLLMRSVGGP +AALTQFMREIGDDVTRSDRYEPDSNRY--SGVLDTTTPQAIATAARKVLLGDVLSPQSRA +QLERWMIDCKPGLNRLRAVLPAQWQAADRPGTSIEEQTNDYALVRPPGRAPLLVAAYYDA +PGVSMEAREAVLREAGKVFVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=UPI0005EBA07D +---VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ +INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP +VGVTTFLIDSGDSVTRLDRIEPLLNEATPGDKRDTTTPYAMNKTITNLVLGNALNESSKQ +QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG +TKASIPERDEEIAQIGQAILQQf +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium abikonense TaxID=86193 RepID=UPI000787A76B +--------KEIEEETGGRLGVALVDRQGALLL-GFNRDERFAMCSTFKAPLAAAVLTGAD +GGKFGLEGTIPFGKEDVLDYAPVVKKNLKRGMSMEELARAAVEVSDNSAANLLLPMLGGP +EGLTAFMRVHGDDVTRLDRNEPTLNENAQGDPRDTTTPAAMAGLMARLFFRD-LKAESAD +RLRAWFNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPTGEEYILAIYLDR +PTIDAKKAEAAIAETARAALN-- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A657C1F5_9SPHN +--------KEIEEETGGRLGVALVDRQGALLL-GFNRDERFAMCSTFKAPLAAAVLTGAD +GGKFGLEGTIPFGKEDVLDYAPVVKKNLKRGMSMEELARAAVEVSDNSAANLLLPMLGGP +EGLTAFMRVHGDDVTRLDRTEPALNENAEGDPRDTTTPAAMAGLMARLFFRD-LKAESAD +RLRAWFNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPTGEEYILAIYLDR +PTIDAKKAEAAIAETARAALN-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. SBT000017 TaxID=1803385 RepID=A0A3M0HXP2_9NOCA +--TAEQTYLDLEARDVARLGVSAVDLASSTTE-SHRGDERFAFCSTFKVYAVGAVLAAVD +AGTLQLTDTRTITAEDKVPESAVDW-EPGSIVTIADLASAALTKSDNTSGNLLIREVGGT +AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTTRSRD +RLLGWMADTQTSDARFRAGVPDRWTSADKTGTGSFGVSNDAGLLLGPDGQKILLIVLSTT +TSEDSSAMNALVADATRTVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI00136577B4 +--AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDSTAANLLLEALGGP +AELDAALTAHGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLVRAELPADWTVGDTSGLGEYASRGDVAVIWRPDAAPIVIAVHSSK +DQQDADADDALISGAARAAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhodococcus TaxID=192944 RepID=UPI0003746846 +---AEKQFAALEQRFDARLGVFAVDLGSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD +AGTLSLTDTRIVEAEDKVPESAIDW-EAGQVVTLEQLCVAALTRSDNTAGNLLIDAGGGT +GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTDGPLSNSSRA +TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLGPDGRRILLVVLSRT +ANPDAAAMNELVADAVREIV--- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=UPI000D17523E +---IDSVIKQAEQQLGAKVGVSVLNANGDSLY-GYNSDQRFPLMSTFKTLACAKLLHDNQ +ITKGMMDKTYPVTAEAILDYAPVFKDKVGTEVSLKDACFATMTTSDNSAANFVLAHIGGA +EGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA +QLTEWMKANKVSNGLFRSVLPQGWVIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG +TEASIPERDKEIAKIGNAIFDRy +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium sp. RSMS TaxID=520734 RepID=UPI0010F9E426 +--------KEIESATGGRLGVALVDSKGALML-GFNRDERFAMCSTFKAPLAAAVLTGAE +GGKFGLEGQISFTRSDLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP +EGLTRFIRAHGDMVTRLDRNEPSLNENVEGDERDTTSPAAMAGLMGRLIFRDL-APESAE +KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTIDARAAEAAIAETARAALD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SVJ1_9BACT +--------------------------------------------------ACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRSMGDEVTQLDRWETDLNEAKPGDPRDTTTPKAMLADLQSLILENVLSRQSRE +QLARWMVANKTGDAKLRAGLPDDWRIGDKTGGGDYGTMNDVAVIWPPDREPLIISVYMTE +SEASFDDRNAAVADIGRAV---- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. ST-F2 TaxID=1490484 RepID=A0A1Q4UEX7_9MYCO +------SFEALEDRYQALIGVYAVDLASSATV-EHRADERFAICSTFKAYAAARILQMAK +DGKANLDAMVPITAGDIIVNSPVLSPAVGARMELREICAAALTQSDNAAGNIMLRTIGGP +SALTDFARSIGDSQTRLDRWEPALNEAAPGDLRDTTTPRALCGGYRAILVGDALSGAAQF +QLQRWMGETATSTRRFRAGLPAGWTSADKTGSGDYGSTNDAGMLIGPKGERVMLTVLIRT +RTRDAGPFNEAVAESVRSV---- +>[subseq from] Beta-lactamase n=2 Tax=Pseudonocardiaceae TaxID=2070 RepID=A0A1Y2MNV1_PSEAH +---------DVEREFGRRIGVHALDTGTGAAV-GHRDGERFLMCSVVKALTAGFVLHRSV +QDPGLLARPVRYDRSDLLEYAPVTEQHLATGLTVEQLCDAAVTVSDNTAQNLLLREAGSP +AELTGWLRGLGDEVTRVDRLEPALNER--DGDLDTSTPAALAATLGLLTTGDALPDAQRD +RLLGWLRGNTTGDRQIRAGVPQGWQVGDKTGSGPLGERNDAGVLFPPQGAPVVLSVFTVP +DDEEPDRGEAAVAAATRTT---- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000DA7AB25 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGGK------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Photobacterium TaxID=2628852 RepID=UPI0013705C10 +--NIDSAIKQAEQQLGAKVGVSVLNGKGDALY-GYNSDQRFPLMSTFKTLACAKLLHDNQ +ITKGMMDKTYPVAAEAILDYAPIFKDKIGTEVSLKEACFDTMTTSDNSAANFVLAQIGGA +AGVTKFLIDNGDNVTRLDRIEPLLNEAAPGDKRDTTTPYAMNETITKLVLGDALNPASKA +QLTQWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG +TQATIPERDKAIAKIGRAIFQQy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. 4M9327F10 TaxID=2502223 RepID=UPI0010F57785 +-----SPLADIERRYGGRLGVFALDTGSGRTL-SYRADERFLMCSTFKGLLAAQILARVD +AGKENLARLVRYTEKDLIFTSPVTKANVALGMPVGALCQAIVEVSDNTAAILLMRSAGGP +AGLTRFIRGLGDTVTRSDRYEPESNKY--SGSLDTTSPKAIATLANRILLGDVLSPTSRA +QLETWMVAARPGLNRIRAALPADWQAADRPGTSVEEETNDYALVRPPGRAPLLIAAYYDA +PGVSMDAREAVLREAGAAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=UPI0009BB3D05 +---VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ +INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP +VGVTTFLIDSGDSVTRLDRIEPLLNEATPGDKRDTTTPYAMNKTITNLVLGNALNESSKQ +QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG +TKASIPERDEEIAQIGQAILQQf +>[subseq from] SGM family class A beta-lactamase n=2 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A657CG29_9SPHN +--------KEIEEETGGRLGVALVDRQGALLL-GFNRDERFAMCSTFKAPLAAAVLTGAD +GGKFGLEGTIPFGKDDVLDYAPVVKKNLKRGMSMEELARAAVEVSDNSAANLLLPMLGGP +EGLTAFMRVHGDDVTRLDRTEPALNENAEGDPRDTTTPAAMAGLMARLFFRD-LKAESAD +RLRAWFNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPTGEEYILAIYLDR +PTIDAKKAEAAIAETARAALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI0011D13000 +---VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD +RGEEKLDRRVFFGEKDLVMPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP +SALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIALGSALSPTSRA +HLTEWMMASRDAAQRLRAGLPAGWRIANKPGTWEGISTNDIGVLFPPNRPPIVVAAYLGK +ARGSVAEQEAVLVDVARIVTR-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD48533 +---VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD +RGEEKLDRRVFFGEKDLVMPFKATKPHLTDGMTVEQLCEAAAIVSDSTAANLLMASFGGP +SALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIVLGSALSPTSRA +HLTEWMMASRDAAQRLRAGLPAGWRIANKPGTWEGISTNDIGVLFPPNRPPIVVAAYLGK +ARGSVAEQEAVLVDVARIVTR-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium sp. P1-5 TaxID=2024617 RepID=A0A5A7ZCW6_9MYCO +---VDQRIGALEKRYNAFVGLYARNLGSDAEL-AHRDGDPFAMCSTFKTYLSARVLQKAQ +AGELRLTDTELVEPADLKPNSPRTEPNAGKPMALSDLCAAALQVSDNTAANMLLRVIGGP +PAITAFARSIGDDRSRLDRWETELNSAVLGDPRDTSTPRALGGGVARVLTGDVLDLPHRK +QLEDWMRANTT--SSMRGGLPPGWTTADKTGSGDYASTNDVGIAFGPNGERVLLAIMTRT +RSAHAEPLRQLIAEVATLVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium sp. GB-56 TaxID=2022106 RepID=UPI000D181C8A +---VNSAIEHAEKQLGARIGVSVVDGKGKQLF-GYNSDQRFPLMSTFKTLACAKLLHDNQ +INDGMMDKTYLINADTILDYAPVFQDKVGTEVSLKDACFATMTTSDNLAANLVLSHIGGP +VGVTTFLIDSGDNVTRLDRIEPLLNEATPGDERDTTTPYAMNKTISNLVLGNALNASSKQ +QLKDWMKANKVSNGLLRSVLPKGWEIADRSGAGGHGSRGITAVVWNEQKQPLVISIYLTG +TKASIPERDKEIAQIGQAILQHf +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudokineococcus lusitanus TaxID=763993 RepID=A0A3N1HRC3_9ACTN +--QVAERLAALEEDFDARLGVMALDTGSGAVV-EHRADERFAAASTLKAFSAAAVLDGD- +---ADLDRVVTWGTGDLVTSSPVTEQHVDDGLPLREVARAAAQDSDNTAANLLYDELGGP +AALQDWLRDLGDTTTRADRPEPGLNDVGPGDERDTSTPRALAGTLERVLLGDALAVDDRE +LLDTWLRGTTTTSALVRAGVPDGWVVADKSGAAAYGTRDVVAVVRPPDRAPLVLALMSDR +RDEDAAYDDALLAAATEVVVD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1L6C492_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGGK------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=UPI000D1581F4 +--QIEPALTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAMNSTLYSLLYGHALSETART +QLKQWMMDNKVSDPLLRAALPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMADLNAAIAKIGQLIFTH- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium chlorophenolicum TaxID=46429 RepID=A0A081RIC4_SPHCR +--------KEIESESGGRLGVALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAVLSGAE +GNKFGLEGQIGFTKADLLDHAPVVKKNARRGMSMEELAAAAVEVSDNSAANLLLPMIGGP +EGFTRYVRAHGDNVTRLDRTEPALNENAEGDERDTTSPAAMAGLMRRLIFTD-LKPESAA +RLRGWLNASSTGGNRIKAGLPKDWTSGSKTGTCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDAKAAEAAIAETARAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00055CB5CA +--SAEQNYLELEARDTARLGVSVLDLATGSTQ-SYRGDERFAFCSTFKVYAVGAALAAVD +AGRLQLTDTRTITAEDKVPESAVD-WAPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSLAAGYRTLLDGDVLTEASRK +QLLEWMGDTETSTARFRAGIAPQWTSADKTGTGSYGVSNDAGLLFGPDGQRILLVVLSAT +TSEDSPAMNPLVADATSAAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 15-649-2-2 TaxID=2023140 RepID=A0A260R1W7_9NOCA +--SAEQNYLELEARDTARLGVNVLDLATGSTQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGKLQLTDTRTITAEDKVPESAVD-WAPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT +AALTDFARALGDTEFRLDRAEPELNTAIPGDPRDTTTPNSLAAGYRSLLDGDVLTEASRK +QLLEWMGDTETSTARFRAGIAPQWTSADKTGTGSYGVSNDAGLLFGPDGQRILLVVLSAT +TSEDSPAMNPLVADATRAAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Henriciella algicola TaxID=1608422 RepID=A0A399RJB4_9RHOB +------PLAGLERESLGEFGVVALEVGGRERL-SHRADERFAMCSTFKWLLGALILRDAD +RDTGLLDRRIAISDADLVFHSPVTRQHVGSALSVSELCAATIKTSDNTAANLLLAGLDGP +EGFTQRLRDLGDTVTRLDRLEPELNENAPGDPRDTTTPRMMAHHLSDFLFGDRLTPSARD +TLRGWMIAADTGLDRLRAGLPEKWVSGDKTGTSSNRANNDVAFAIPPEGKPIVIASYINV +PNPVSKEANRLHAQIAKLA---- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A657BXG5_9SPHN +--------KEIEEETGGRLGVALVDRQGALLL-GFNRDERFAMCSTFKAPLAAAVLTGAD +GGKFGLEGTIPFGKDDVLDYAPVVKKNLKRGMSMEELARAAVEVSDNSAANLLLPMLGGP +EGLTAFMRVHGDDVTRLDRTEPALNENAEGDPRDTTTPAAMAGLMARLFFRD-LKAESAD +RLRAWFNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPTGEEYILAIYLDR +PTIDAKKAEAAIAETARAALN-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Ant20 TaxID=104605 RepID=A0A0A6CYV4_9SPHN +-------VADYETASGGHVGLYARNLMTGRAI-AWRADERFVMCSTFKASLAACVLDGVD +RGRFRLADEIALVPADLQDHAPVARQNLARGMSLGEMCRAAVEQSDNSCANILLQRIGGP +AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMAATIGRLTRGPALSPSSRA +LLMLWLRQCRTGDARLRAGLPRGWAIGNKTGNNGKDAAGDVGVLWRDPDTPIIISVYTRG +GTPTEAQFKTLFSEVARGVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. Ant20 TaxID=104605 RepID=UPI000FE142D6 +-------VADYETASGGHVGLYARNLMTGRAI-AWRADERFVMCSTFKASLAACVLDGVD +RGRFRLADEIALVPADLQDHAPVARQNLARGMSLGEMCRAAVEQSDNSCANILLQRIGGP +AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMAATIGRLTRGPALSPSSRA +LLMLWLRQCRTGDARLRAGLPRGWAIGNKTGNNGKDAAGDVGVLWRDPDTPIIISVYTRG +GTPTEAQFKTLFSEVARGVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia heleia TaxID=634127 RepID=UPI000693656F +--AAESPLADIERRRGGRLGVFAIDTGSGRTL-SHRADERFLMCSTFKGLLAAQILARVD +SGAERLDRLVRYTETDLVFTSPVTKANVARGMSIDALCRAILVESDNTAAILLMRSAGGP +AALTRFVRDLGDTVTRSDRYEPDSNRY--RGLLDTTTPKAIATTVQRLLLGDVLSAGSRA +QLERGMADCKPGLNRIRAVLPAGWQAADRPGTSVESETNDYALVRPPGRAPLLVAVYYDA +PGVGMDAREAVLREAGTAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=UPI000D157CE6 +--NIDSAIKHAEQQLGAKVGVSVLNANGDSLY-GYNSDQRFPLMSTFKTLACAKLLHDNQ +ITQGMMDKTYPVTAEAILDYAPVFKDKVGTEVSLKDACFATMTTSDNSAANFVLAHIGGA +EGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA +QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG +TEASIPERDKEIAKIGNAIFERy +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium sphagni TaxID=1786 RepID=A0A255E1Z6_9MYCO +---LEQRIAALETRHNAFIGLYSRNLDSNLSV-MHRVDDPFAMCSTFKAYLSGRVLQKAQ +AGELRLTDTVVVDPDLLRANSPRTEPNVGKPMALSDLCAAALQVSDNTAANLLLRVIGGP +PAITAFARSIGDARTRLDRWETELNSALPGDPRDTSTPRALGGGVSTLLTGNVLDDVHRK +QLEDWMRANST--SSIRAGLPAGWTTADKTGSGDFASTNDVGIAFGPNGERVLLAIMTRT +QSANAPALRDLIGEVTTAVL--- +>[subseq from] Beta-lactamase n=1 Tax=Carnobacterium maltaromaticum TaxID=2751 RepID=A0A2N5JKI0_CARML +-kTIDSNLKKLEKEYEATLGIYAIDTETNKTI-NYNGEQRFAFASTYKALAGGLVLDKFN +--WDELNQTIMIHQEDLVDYSPITEKYVGIGMPLKDIIGAAMEYSDNTAGNILFDQLGGP +VGFQKELEKLGDHTTESVRYEPELNDAIPGDRRDTSTPKAIALDLKKLTADKTLAPDKLT +FYKKQLVENKTGGNLIRAGIPTDVLVDDKSGAASYGTRNDIAVLYPSNRKPIVLVIFSNK +TNKDDAYQDELIAKSAKLVSDYf +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium sp. EP60837 TaxID=1855519 RepID=A0A173KS26_9SPHN +--------RTIEQESGGRLGIALVDNKGALLL-GFNRDERFAMCSTFKAPLAAAVLMGAD +AGRFGLDGQVAFTQADILDHAPVVKANGKRGLSMAELAEAAVEVSDNSAANLLLPMIGGP +EGLTAFVRAHGDTVTRLDRTEPALNENMEGDPRDTTSPAAMASLISRLLFRDM-KAESAS +RLMTWLNASTTGDERIKAGLPPGWTSGSKTGSCGS-AFNDVALVKAPSGEQYVLAIYLDR +PTVDAKAAEAAIAQAARAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. SG570 TaxID=2587113 RepID=UPI0014476772 +---VEDQLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD +RGEEKLDRRIFFGEKDLVMPFKATKPHIADGMTVEQLCEGAAIVSDSTAANLLMANFGGP +SALTAYLRSIGDQITRIDKTELTLNIVKPGETHDTTSPRAMVGTLQRIVLGSALSPTSRA +HLTEWMMASRDAAQRLRAGLPAGWRIANKPGTWEGIATNDIGVIFPPNRPPIVVAAYLGK +ARGSVVEQEAVLAHVARIVTR-- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderiaceae TaxID=119060 RepID=A0A1B4LLH4_9BURK +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3Z8WWV4_ECOLX +---MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ +KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP +DAVTQFMRGIGDHVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTAPPLTPANRA +VLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVEIFITQ +TEASMK----------------- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia sp. KJ006 TaxID=416344 RepID=I2DW12_9BURK +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. 66-54 TaxID=1895845 RepID=A0A1M3PT48_9SPHN +--ALRQALADLEGRAGGKAGVCVLDCRDGALA-GHRLDERFTMCSTFKLPLAALVLARMD +AGAIAPDATLPIGPADPVGHAPAVRAQLAEGMAVLELCEAAQTQSDNGAANILLRALGGP +PALTAFFRSLGDEVTRLDRYEPALNTSHDGDPRDTTTARAMARSLQAILTGTVLAPASRA +RLIAWMIATRTGLKRLRGGLPADWRAGDKTGTAAAGKANDVAICWHPRREPFIVTAFYET +AAGPQPEDDAVVAQIGRIAS--- +>[subseq from] Beta-lactamase n=1 Tax=Aliivibrio logei TaxID=688 RepID=A0A1B9P2F9_ALILO +--SLNDTIIALEKQTSGDIGVAVLDTKTNQIW-SYKGNQRFPMMSTFKTLACAKMLHDAD +KKIINKKTETAIAQKDLIPWSPITEKYVGKSISTEKACEATMLMSDNTAANIVLQQIGSP +SSLTAFLRLMGDSTTQLDRIEPTLNEAKKGDIRDTTTPIAMVNTINKLLLGNTLTTTDKV +TLKKWMMDNKVSDPLLRSILPIHWSIADRSGAGGYGSRGITAIIWNEHRLPLIISIYLTQ +TDLTLAERNDIIVHVGSALFSHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacter agglomerans TaxID=549 RepID=L0HP91_ENTAG +----------------GRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSEAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKAVGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGY------------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=A0A2T3K7C8_PHOPO +--QIEPALTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAMNSTLYSLLYGHALSETART +QLKQWMMDNKVSDPLLRASLPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMADLNAAIAKIGQLIFTH- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia sp. P2 TaxID=882856 RepID=UPI00030C9093 +-------MADVERTYARTIGVHVLDTGTGRSA-GHRDGDRFLMCSVTKALMAGFTLHRSL +SDPGLLDRPVRYGRADLLEYAPVTNRNLATGMTVAQLCEAAVTVSDNTAHNLLLREVGSP +AELTAWLRTTGDTVTRSDRAETALNDR--DGERDTSTPAALASTLRTLVLGDALPAPQRD +RLAGWLRANTTGDRQIRAAVPAGWGVGDKTGSGPRGERNDSGVLYPPDGAPLVLTVFTVP +ADADEQRGEAAVAAAARAAVA-- +>[subseq from] Beta-lactamase n=2 Tax=Photobacterium angustum TaxID=661 RepID=Q1ZR52_PHOAS +---VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ +INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP +VGVTTFLIDSGDSVTRLDRIEPLLNEATPGDKRDTTTPYAMNKTITNLVLGNALNESSKQ +QLKDWMQANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG +TKASIPERDEEIAQIGQAILQQf +>[subseq from] Beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=Q9REJ3_VIBHA +--KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD +NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRFEHACEAAMLMSDNSAAHIVLRSIWGV +AGGTSFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI +QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE +TDLSLQARDQVIAQVSQLILD-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium fuliginis (strain ATCC 27551) TaxID=336203 RepID=A0A292ZFA8_SPHSA +--------KEIESATGGRLGVALVDSKGVLML-GFNRDERFAMCSTFKAPLAAAVLTGAE +GGKFGLEGQISFTRSDLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP +EGLTRFIRAHGDMVTRLDRNEPSLNENVEGDERDTTSPAAMAGLMGRLVFRDL-APESAE +KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTIDARAAEAAIAETARAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050C78D0 +--SAEQNYLELEARDTARLGVKVLDLATGSSQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSLAAGYRTLLDGDVLTEASRK +QLLEWMGDTETSTARFRAGIAPQWTSADKTGTGSYGVSNDAGLLFGPDGQRVLLVVLSAT +TSEESPAMNPLVADATRAAVE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. Leaf343 TaxID=1736345 RepID=A0A0Q5PRY3_9SPHN +--AVADPIADYERATGGRIGVHALNVRTGKTL-SWRADERFIMCSSYKASLAAFVLSRVD +RGEEKLDALVPYTAKDTLEWGPIAKANLARGMTVEAMCKAAVEISDGACANLLMARSGGP +AALTAFLRSIGDTVTRVDHYEPALDRVPSGGPDDSTTPAAMATTLRKVIVGNVLSDRSKA +LLTSWLVGNQT-NPRLRGGLPRSWRIGNKTGHSGRDMAGDIAVAWPRPDTPIVIAVYTRG +GRPSEKQFDKAFAGIGRLVAK-- +>[subseq from] Beta-lactamase n=2 Tax=cellular organisms TaxID=131567 RepID=A0A094ZTL7_9PROT +-------ISQYENETGGHVGFYAENTKTGATL-GWRTDERFVMCSTFKASLAACVLARVD +GGLDALERPLSYTAADIGDYAPVAKANLAKGMTIRELCAGAVEQSDNTCANLLLAHIGGP +SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGPVLSAPSRT +ILTDWLIRCRTGEHRLRAGLPSAWKIGDKTGNNGKYAAGDIAVIWPHPETSIVVCAYTRG +GHPTEQQLSSVFAGIGKLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus coprophilus TaxID=38310 RepID=A0A2X4X341_9NOCA +--ALDSRLAQIENQHKVRLGVLGHTPATGRVY-AHRGDERFAMCSTFKMYAAAGILRLES +LGKLSLDETVPVEPADIVVNSPVTTEHQGRVMTVGGLCEAALTRSDNTAANLLLRRLGGP +DTVTALARSVGDGATRLDRWEPELNEAGRGDERDTTTAVGLGTGCRELLVGAGLPPPQQR +MLTGWMRASLTSGKRIRAALPRDWTAADKTGGGLHGTVNDAGVVWSPSGNPLVLVVLSDS +TTPDVPIDDA------------- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000CB62220 +-----QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE +NEGLDLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMAMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPDDVRDTTTPNSMVVTLNELVYGNTLSQESKL +KLKNWMIGNKVSDGILRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE +TEFTIQERDKVINEIGQLIFDAy +>[subseq from] Beta-lactamase n=1 Tax=Yangia pacifica TaxID=311180 RepID=A0A2U8HA55_9RHOB +-eALSDTVARIEEQLGARVGVSLVDTGSGWSW-FHRGDELFLMNSTVKVPVCGAILARRD +AGTLSLSDALPVREVELVPYAPITETRVGGTMTLDELCLAAIDMSDNVAANILIGHLGGP +EAVTQFFRSVGDPTSRLDRLEPELNVFAPGDARDTTSPAAMSEALRALLLGDALSPQARG +QLAEWMRHGGVTGALLRAEAEDDWLILDKSGSGRH-TRNLVAVIQPEGEAPWIATMFVSD +TDAEFEARNAALKDLGGAVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Inhella inkyongensis TaxID=392593 RepID=UPI00110E413D +--AFSTAVAALEQQHGGRLGVALLDTASGAVS-GHRLDERFALCSTFKLLLAAEVLRQSD +QGRLRLHDWQAFGRTPWVPHAPVTQAHKKHGMVLGALAEATQKTSDNMAANLLLRRLGGP +AALTQALREQGDAVTRIDRWEPEMNRVPPGEVRDTTSPAAMARSAAHWVLGDVLKPASRT +RLQRWMKDTETGLDRLRAGLPEAWVVGDKTGTGLPDQINDVAVIWPPGRTPWVLSAYYAA +PAQGREDFKAVLAEVGRLA---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=F4Y5N4_KLEOX +------------------------------------------MCSTSKVMAAAAVLKQSE +SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLILVTYFTQ +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia sp. GAS332 TaxID=1882750 RepID=A0A1N6LTT4_9BURK +------PLADIERRNGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLSRVD +AGKEDPARLVRYTEKDLVFTSPVTKAHVAQGMSVGALCQAIVEVSDNTAAVLLMRGAGGP +AGLTQFVRSLGDTVTRSDRYEPESNKY--SGVLDTTTPRSITKSASQILLGNVLSPQSRA +QLENWMIACTPGLNRLRAALPPDWIAGDRPGTSVEEETNNYAIVRPPGRAPLLIAAYYDA +PALAMPAREAVLREVGAAFV--- +>[subseq from] Uncharacterized protein n=2 Tax=Streptomyces sp. HGB0020 TaxID=1078086 RepID=S2Y6B6_9ACTN +------------------------------------------MCSTFKTLAAAAVLRDLD +RHGEVLARRIHYTRDDLVDGAPITGKNLAHGMTVAELCDAAIRYSDNSAGNFLLRLLGGP +TAITRFSRSLGDRVTRLDRWEPELNSAEPGRRTDTTSPRAIGGSYARLVLGCALNAPDRA +RLTHWLLTNTTGDHRIRAGLPASWTVGDKTGSGSYGTTNDVAVAWTDDGDPVVVAVLSTK +RDQDAAWDDALLSGAAAIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Ax-1719 TaxID=2608334 RepID=UPI00141D8A1E +-----SPLADIERRQGGRLGFYAIDTGTGRTL-EHRAGERFLMCSTFKGMLAAQVLARVD +AGKEQRERLVHYTAQDLIFTSPVTKANVARGLPVHTLCQAIVEQSDNTAAILLMRSVGGP +AALTQFMRGIGDSVTRSDRYEPDSNRY--SGVLDTTTPQAMATAARAVLLGDVLSLQSRA +QLERWMIDCKPGLNRLRAVLPAGWQAADRPGTSVEEETNDYALVRPPGRAPLLVAAYYDA +PGVSMDAREAVLREAGKVFVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. BL23I1N1 TaxID=1938802 RepID=UPI000E75B8A2 +------PLADIERRNGGRLGVFAIDTGSGRTL-AYRADERFLMCSTFKGLLAAQVLSRVD +AGKEDLARLVPYTEKDLIFTSPVTKAHVAEGMSVRAMCQAIVEVSDNAAAVLLMRSAGGP +AGLTQFVRGLGDTVTRSDRYEPESNKT--SGVLDTTTPRSITKTASQILLGHVLSPQSRA +QLESWMITCKPGLNRLRAALPPDWIAGDRPGTSVESETNDYAIVRPPGRAPLVIAAYYDA +PALGMHAREAVLREVGEAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Aliivibrio sifiae TaxID=566293 RepID=A0A2S7XC76_9GAMM +--SLTKSIEAIELASSGQIGVSVLDTSNNQSW-SYKGDQRFPMMSTFKTLACAQMLYNSS +NNLLDKDSLTRITKESIIPWSPITEKLIGETISTESACQATMLMSDNTAANIVLTKIGSP +TSLTLFLRLIGDNITRLDRIEPALNEAQKGDIRDTTTPNAMTNTLNELLFGQTLNTKDKR +TLKAWMVDNKVSDPLLRSILPAKWSIADRSGAGGFGSRGITAIVWNNKRAPIIISIYLTQ +TNLDMASRNQVIVEVGNAIFKEf +>[subseq from] Beta-lactamase n=2 Tax=Vibrio TaxID=662 RepID=A0A2K1CFC2_9VIBR +--DLTASLTEIERESTGRIGVAVIDTKDNKLW-NYHGHDFFPMMSTFKTLACAHMLYQVD +RGQIKTAKSIPVTKDDLVNWNPVTEHFVGSTMTLQSLCNAAMTMSDNAAANLVLKAIGGP +ESLTAFLQRNGDKATRLDDIEPQLNYVDIGSKRNSTTPLTMMKTIEKLTLGSVLSEQSKR +QLLLWMKANMVSDGLLRAVVPKDWQVADRSGGGVNGSRTYTGMIWRKNRDPIFIGIFVAR +TKKTVPELNKLVRTISVAVLEEf +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2L1TH66_ECOLX +---------------------------------------------TFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQA-------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter sp. DE0047 TaxID=2584949 RepID=UPI0011A0C826 +---LQAFLKQEEIRLPGKIGMSIVNADGQPIF-GYRQSERFPLTSTFKVLACAALLDRLH +KTAGSLDETVTIKPDELLSYSPITKNYVAPAITLHTLCSAAVSYSDNTAGNSILTYLGGP +DAITRFMRESGDDVTRLDRTEPTLNEATPGDERDTSTPERMASGLHTLLATPRLTAPHRE +MLEQWMRDDKVADNLLRAALPEGWAIADKTGAGGYGSRAIIAAVYPKGAQPVYMAIYITQ +TDAEMKMSDGMIKRIGERVF--- +>[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea sp. FMUSA5-5 TaxID=2720023 RepID=UPI00143B4F0C +--AVEEELRALEVAFEGRIGAYAVDTGTGRSV-AYRAGERFPLLSTFKAPLCAAVLCRAR +RERGLMGRRLRWRACDMTPNSPVTGRHLEDGLTVAELCAAAVTRSDGTASNLLMELIGGP +RGMTAFFRGLGDPVSRVDRWHPGLNEWVPGDERDTTTPAAMAGVLRALAVGGALHPEDRE +RLVGWLLASQVGAGRVPAGLPAAWTVGHKTGTNSFGGGHDVAVVWTEAGAPIVMAVYTNR +TP-GLPTDDSVLARTAKVLVR-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. EC080619-01 TaxID=1096856 RepID=A0A0P0SBG8_9PSEU +--------DGVEREFGRRIGVHVLDSGTGATA-GHRDGERFLMCSVVKALMAGFVLHRSV +ADPALLDRPVRWGRADLLEYAPVTSRHVDSGLSVAQLCEAAVTVSDNTAHNLLLREVGSP +ADLTAWLRSTGDGVTRADRYETALNDV--DGDRDTSTPAALAATLRALTTGDVLPSAQRD +RLVGWLRANTTGDEQIRAGVPDGWQVGDKTGSGPLGEKNDAGVLFPPQGAPVLLTVFTVP +ADPSAPDDDRGAAAVAAA----- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000E0E75A4 +---VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD +RGEEKLDRRVFFGEKDLVMPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP +SALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMAGTLQRIVLGSALSPTSRA +HLTEWMMASRDAAQRLRAGLPVGWRIANKPGTWEGIATKDIGVIFPPNRPPIVVAAYLGR +ARGSVADQEAVLAEVARIIT--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI00084A2EFB +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMGSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter tropicalis TaxID=104102 RepID=A0A252A7Z1_9PROT +-------ISQYENETGGHVGFYAENTKTGATL-GWRTDERFVMCSTFKASLAACVLARVN +GGLDALERPLSYTAADIGDYAPVAKANLAKGMTIRELCAGAVEQSDNTCANLLLAHIGGP +SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGPVLSAPSRT +ILTDWLIRCRTGEHRLRAGLPSAWKIGDKTGNNGKDAAGDIAIIWPHPETSIVVCAYTRG +GHPTEQQLSSVFAGIGKLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Desertifilum sp. IPPAS B-1220 TaxID=1781255 RepID=A0A1E5QKA0_9CYAN +-nQLRDRIEQISRTAQGQVGVTATVLETGESV-TLNGEQQFPMQSVYKFPIAMAVLSQVD +RGTLNLDRKVRVETRDFALHSPIRDQHPQGVLTLAELLKYMVSESDNTACDVLLGLVGGP +EVVTQYLRDLGINDMVVANTEREIGQDNAVQYRNSATPDAAVALLSRLHEGQGLSASSQA +LLLQWMTETPTGLKRIKGLLPEGTVVAHKTGTSGTAATNDVGLVTLANGRHLAIAVFVSD +STADQATREAAIAQIARAAWDRw +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium herbicidovorans (strain ATCC 700291 / DSM 11019 / NBRC 16415 / MH) TaxID=1219045 RepID=A0A086PCP3_SPHHM +--------RTIEEETGGRLGVALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAVLMGAD +AGRFGLEGQVAFTDKDLLDHAPVVKANRKRGLSMEELAKAAVEVSDNSAANLLLPMIGGP +EGLTAFVRAHGDTVTRLDRLEPALNENTPGDPRDTTSPAAMAGLIGRLLFRDM-QAESAA +RLTGWLNASKTGDKRIKAGLPPGWTSGGKTGSCGT-AFNDVALVEAPSGERYILAVYLDR +PTGDAKAADAAIAEAARAALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. CNPSo 3157 TaxID=2654983 RepID=UPI00128E44CA +--AAESPLADIERRNGGRLGVFAIDTGSGRTL-SHRADERFLMCSTFKGMLAAQILARVD +SGAERLDRLVHYTEKDLIFTSPVTKANVARGMSIDELCRAILVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--RGVLDTTTPKAIATTAQRLLLGDVLSASSRV +QLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVESETNDYALVRPPGHAPLLVAVYYDA +PGVGMNAREAVLREAGTAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. STIS6.2 TaxID=1379700 RepID=UPI000D1428DD +-------VADYETASGGHVGLYARNLMTGRAI-AWRADERFVMCSTFKASLAACVLNRVD +RGRARLADRIALSPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILSQRIGGP +AALTGYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMAATIGRLTRGPVLSPSSRA +LLMLWLRQCRTGAARLRAGLPQGWVIGNKTGNNGRDAAGDVGVLWRDPDTPIIISVYTRG +GTPTEAQFKTLFSKVARGVA--- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A132E1X6_BURVI +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAALREAGSAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia sp. ESNIH1 TaxID=1985876 RepID=A0A2S4QQX4_9ESCH +---LQAFLKQEETRLPGKIGMSIVNAEGQPIF-GYRQNERFPLTSTFKVLACAALLDRLH +KTAGSLNETVTIKPDELLSYSPITKNYVAPAITLQTLCSAAVSYSDNTAGNSILAYLGGP +EAITRFMRESSDTVTRLDRTEPTLNEATPGDERDTSMPERMASGLHTLLATPRLTPSHRT +TLESWMREDKVADNLLRAALPKGWTIADKTGAGGYGSRAIIAAVYPTGEKPFYMAIYITQ +TDAEMKVSDGVIRAIGEWVF--- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. AEW013 TaxID=2572915 RepID=A0A560X3U2_9SPHN +--AVADPIADYERATGGRIGVYAVNVKTGKSI-SWRSDERFIMCSSYKASLAAFVLARVD +RGEERLDALVHYTAKDTLEWGPIAKANLAKGMTVEAMCKAAVEISDGACANLLMARSGGP +AALTTFLRSIGDGTTRVDHFEPALDRVPSGGPDDSTTPAAMAATLQKFVLGSVLSDRSKA +LLTRWLIGNQT-NHRLRAGLPTSWRIGNKTGHSGRDMAGDIAVAWPRPDTPIVVAVYTRD +GKPTERQFDKAFAGIGSLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL23I1N1 TaxID=1938802 RepID=A0A3R7KZZ7_9BURK +------PLADIERRNGGRLGVFAIDTGSGRTL-AYRADERFLMCSTFKGLLAAQVLSRVD +AGKEDLARLVPYTEKDLIFTSPVTKAHVAEGMSVRAMCQAIVEVSDNAAAVLLMRSAGGP +AGLTQFVRGLGDTVTRSDRYEPESNKT--SGVLDTTTPRSITKTASQILLGHVLSPQSRA +QLESWMITCKPGLNRLRAALPPDWIAGDRPGTSVESETNDYAIVRPPGRAPLVIAAYYDA +PALGMHAREAVLREVGEAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Brucellaceae bacterium VT-16-1752 TaxID=2487907 RepID=A0A3P1UKE6_9RHIZ +---VEDRLRELEIRSGGHLGVAVLDTATGQVV-GNRLDERFALCSTFKALAIAFTLARVD +RGEEKLDRRVFFGEKDLVMPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP +SALTAYLRSIGDHATRIDKTELALNIVKPGETHDTTSPRAMVGTLQKIILGSVLSPSSRG +RLTAWMMASRDAAARLRAGLPEGWRIANKPGTWNGISTNDIGVLFPPDRPPIVVAAYLGR +ARGTVPQQEAILSEVARIVAN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus sp. p52 TaxID=935199 RepID=A0A1B2UJI5_9NOCA +---VDERLREIKDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA +EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP +GAVTAFARSVRDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Lysobacter sp. A03 TaxID=1199154 RepID=UPI000696A07E +--DLSSDVAELEKSHSAKIGVALFD-KDGRFLgGHRANERFAMCSTFKLPLAALVLSRID +RGEENAERRLHYDSNMIVEYSPAAERYLPTGMTVLEAAQASVQLSDNGTANLLLREVGGP +PGVTRYFRDLNDLTTRLDRKEPEMSSNIPGDMRDTTTPTAMGKTVSHVLYGEALKPSSAS +LLKRWLIGNQTGDSTLRAGFPKDWVVGEKTGTCSNGGRNDIGFFAVDGR-EYVVAVYTTA +PSFTPEGRNELVASTARVI---- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium vermicomposti TaxID=529005 RepID=UPI00142265F7 +------NPREIEKETGGRLGVALIDSKGALLL-GFNRDDRFAMCSTFKAPLAAAVLMGAE +AGKFGLEGQVAFSKADLQDYAPVVKANMKRGMSMAELAEAAVEVSDNSAANLLLSFVGGP +EGLTAFMRSHGDAVSRLDRNEPDLNENAEGDVRDTTSPAAMAGLMARLIFQNM-QPDSAT +LLREWLNGSTTGDRRIKAGLPEGWTSGGKTGSCGT-AFNDVALVKAPSGEEYVLAIYLDR +PTVDAKAADSAIAEAARAA---- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia alni TaxID=33907 RepID=A0A2N0IFY7_9PSEU +------ALADVEREYARTIGVHVLDTGTGAAA-GHRDGDRFLMCSVVKALMAGFVLHRSL +SEPGLLDRPVRYGRADLLEYAPVTTRNLAAGMTVAQLCEAAVTVSDNTAHNLLLREVGSP +AELTAWLRTTGGTVTRSDRAETALNDR--DGERDTSTPAALASTLRTLVLGDALPPAQRD +RLTGWLRANTTGDRQIRAAVPAGWTVGDKTGSGPLGERNDSGVLYPPDGAPLVLTVFTVP +ADADTARGEAAVAAAARAAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio sp. EL58 TaxID=2107582 RepID=UPI000EFC2970 +---VLETVEAIELSSSGTIGVSVLDTETNTTW-SYKGDHRFPMMSTFKTLVCAQMLYNSS +NELLDKDALTRITKESIIPWSPITEKLIGETISTEKACEATMLMSDNTAANIVLAEIGTP +SSLTLFLRLIGDNITRLDRIEPALNEAQKGDVRDTTTPNAMTNTLNELLFGQTLNTKDKR +TLKAWMVDNKVSDPLLRSILPAKWSIADRSGAGGFGSRGITAIVWSNKRAPIIISIYLTQ +TNLDMASRNQIIVEVGNAIFKEf +>[subseq from] Beta-lactamase n=1 Tax=Carnobacterium divergens DSM 20623 TaxID=1449336 RepID=A0A0R2HXT3_CARDV +----SLNFEKLEKKYDATLGVYGLDTETNKVV-AYNEDQRFAFASTYKALAGGLVLNESS +--WDELNQTIMIKKEDLVTYSPITEKYVDIGMPLKELISAAIQYSDNTAGNFLFKQLGGP +KGFQTKLAELGDYTTDSSRFETELNEATPGDIRDTSTPKEIALDLKKLAIDHKLPTDKLE +FYKKQLIENTTGSKLIRAGIPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK +EQQESDYNDELIAETAKIVSDDf +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium leiognathi subsp. mandapamensis TaxID=48408 RepID=A0A0N0V8Y6_PHOLD +--NIDSAIKQAEQQLGAKVGVSVLNGKGDALY-GYNSDQRFPLMSTFKTLACAKLLHDNQ +ITKGMMDKTYPVAAEAILDYAPIFKDKIGTEVSLKEACFDTMTTSDNSAANFVLAQIGGA +AGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLILGDALNPASKA +QLTQWMKSNKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG +TQATIPERDKAIAKIGRAIFQQy +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium sp. SA916 TaxID=1851207 RepID=A0A2K0XW19_9SPHN +--------KEIESATGGRLGVALVDSKGALML-GFNRDERFAMCSTFKAPLAAAVLTGAE +GGKFGLEGQISFTRSDLLDYAPVVRKNAKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP +EGLTRFIRAHGDMVTRLDRNEPSLNENVEGDERDTTSPAAMAGLMGRLIFRDL-APESAE +KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTIDARAAEAAIAETARAALD-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=A0A1G8J1H6_9BURK +------PLADIERRHGGRLGVFAIDTGSGRTL-SYRADERFLMCSTFKGLLAAQILARVD +TGKENLARLVRYTAKDLIFTSPVTKANVSQGMSVGALCQAIVEVSDNTAAILLMKSAGGP +AGLTQFVRDLGDTVTRSDRYEPESNQY--NGVRDTTSPRAIVKLANRILLGDVLSPLSRT +QLESWMIAAKPGLNRIRAALPADWLAADRPGTSVEEETNDYALVRPPGRAPLLVATYYDA +PGVSMDSREAVLREAGTAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. 20006FA TaxID=2056888 RepID=A0A197BST8_9SPHN +--------KEIESATGGRLGVALVDSKGALML-GFNRDERFAMCSTFKAPLAAAVLTGAE +GGKFGLEGQISFTRSDLLDYAPVVRKNAKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP +EGLTRFIRAHGDMVTRLDRNEPSLNENVEGDERDTTSPAAMAGLMGRLIFRDL-APESAE +KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTIDARAAEAAIAETARAALD-- +>[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A5C7WNW2_9MYCO +---IEDRLVALEQKYDAVVGLYGADLDSDRTV-SHRDGDMFAMCSTFKAYLAARVLYGAQ +QGELRLDDTIVVNREALQPHSPVTEREVGRAVPLGTLCAATLQQSDNAAANLLLARIGGP +PTITAFARLIGDERSRLDRWEVDLNSALPGDPRDTSTPRALGGGIRTLLTGTVLDETHRR +QLDEWMRGNVTSARSIRAGLPAGWTSADKTGSGDYASTNNVGIAYGPAGERILLSIMTRT +RGPEAPALQPLIAEVTALVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=UPI000D1679C1 +--QIAPELTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAMNSTLYSLLYGHALSETART +QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMADLNAAIAKIGQLIFTH- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium TaxID=165695 RepID=UPI0005619E6A +--------KEIETESGGRLGVALVDGKGALIL-GFNRDERFAMCSTFKAPLAAAVLAGAE +GGKFGLEGQISFAKADLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP +EGLTRFIRAHGDMVTRLDRNEPSLNENAEGDERDTTSPAAMAGLMGRLIFRDL-APESAG +KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDAKAAEAAIAETARAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCD998 +---VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD +RGEEKLDRRIFFGEKDLVAPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP +SALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIVLGSALSPTSRA +HLTEWMMASRDAAQRLRAGLPVGWRIANKPGTWEGIATNDIGVIFPPNRPPIVVAAYLGR +ARGSVADQEAVLAEVPRIIT--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=UPI001329F500 +---VDERLKEIEDRYAVRLGVVAQSPVTGRVH-THRADERFAICSPFKVYAAAAILRLEA +EGTLRLDETLPIDPDDIVVNSPVTSEHQGRVLPLDRLCEAALTRSDNTAGNLMLQRIGGP +EAVTAFARSVGDGTTRLDRWEPELNEAARGDQRDTTTAAGLSRGFGEVLLGSGLPAPQQR +TLLGWMRATTTSDTRIRGGLPSGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLVILSDS +TTPDAP----------------- +>[subseq from] Beta-lactamase n=3 Tax=Sphingobium TaxID=165695 RepID=A0A081SXW0_9SPHN +--------KEIETESGGRLGVALVDGKGALIL-GFNRDERFAMCSTFKAPLAAAVLAGAE +GGKFGLEGQISFAKADLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP +EGLTRFIRAHGDMVTRLDRNEPSLNENAEGDERDTTSPAAMAGLMGRLIFRDL-APESAG +KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDAKAAEAAIAETARAALD-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI00084A2DE2 +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMGSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=UPI000D160BA3 +--QIEPALTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TQRIHLNKPVLVKQSDILGYAPITKDRVGTTMTLAQLCDATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAMNSTLYSLLYGHALSETART +QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMADLNAAIAKIGQLIFTH- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia eburnea TaxID=1189126 RepID=A0A2S4M2A6_9BURK +------PLTDIERRHGGRLGVYAIDTGTGHTL-EHRADERFLMCSTFKGMLAAQVLARVD +AGKERLDRLVHYTAQDLIFTSPVTKANVARGLPVHTLCQAIIEQSDNTAAILLMRGAGGP +AALTQFMRGIGDDVTRSDRYEPDSNRY--SGVLDTTTPRAIATAARATLLGDVLRLASRE +LLERWMIDCKPGLNRLRAVLPAGWLAADRPGTSVEEQTNDYALVRPPGRAPLLVAAYYDA +PGMSMDEREAVLREAGKVFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus coprophilus TaxID=38310 RepID=UPI000A074D93 +--ALDSRLAQIENQHKVRLGVLGHTPATGRVY-AHRGDERFAMCSTFKMYAAAGILRLES +LGKLSLDETVPVEPADIVVNSPVTTEHQGRVMTVGGLCEAALTRSDNTAANLLLRRLGGP +DTVTALARSVGDGATRLDRWEPELNEAGRGDERDTTTAVGLGTGCRELLVGAGLPPPQQR +MLTGWMRASLTSGKRIRAALPRDWTAADKTGGGLHGTVNDAGVVWSPSGNPLVLVVLSDS +TTPDVPIDDA------------- +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis (strain G4 / LMG 22486) TaxID=269482 RepID=UPI000766E13C +----ESPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=A0A385LJH7_RHORH +---VDERLKEIEDRYAVRLGVFAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLES +EGSLRLDETFPIDPDDIVVNSPVTSEHQGRVLPLDRLCEAALTRSDNTAGNLMLQRIGGP +EAVTAFARSVGDGTTRLDRWEPELNEAARGDQRDTTTAAGLSRGFGEVLLGSGLPAPQQR +TLLGWMRATTTSDTRIRGGLPSGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLVILSDS +TTPDAP----------------- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium ahvazicum TaxID=1964395 RepID=A0A2K4Y8N9_9MYCO +------RLAELERQYDAYIGLFAADPGSGRTC-AHRDDDPFAMCSTFKVYAAARVLQMAQ +HGELDLQQPIFIDPAALLPNSPVTAPRAGNTVPLAQLCAAALQRSDNVAANLLLAQIGGP +PAITDFARSIADERTRLDRCEIELNTAIPGDPRDTSTPRALGTGVQNLLSGTVLGDAQRR +QLEQWMRDNVT--SSMRAGLPPGWTSADKTGTGDYGSTNDVGMVYGPAGQRALLSVMTRS +RSANADALRPLIVEVTKSVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Acetobacter tropicalis TaxID=104102 RepID=UPI0002E2F280 +-------ISQYENETGGHVGFYAENTKTGATL-GWRTDERFVMCSTFKASLAACVLARVD +GGLDALERPLSYTAADIGDYAPVAKANLAKGMTIRELCAGAVEQSDNTCANLLLTHIGGP +SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGPVLSAPSRT +ILTDWLIRCRTGEHRLRAGFPSAWKIGDKTGNNGKDAAGDIAVIWPHPETSIVVCAYTRG +GHPTEQQLSSVFAGIGKLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium leiognathi subsp. mandapamensis TaxID=48408 RepID=A0A2T3KVZ8_PHOLD +--NIDSAIKQAEQQLGAKVGVSVLNANGDSLY-GYNSDQRFPLMSTFKTLACAKLLHDNQ +ITKGMMDKTYPVTADAILDYAPVFKDKVGTEVSLKDACFATMTTSDNSAANFVLAHIGGA +EGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDGLNPASKA +QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG +TEASIPERDKEIAKIGNAIFERy +>[subseq from] Beta-lactamase n=1 Tax=Aliivibrio wodanis TaxID=80852 RepID=A0A5Q4ZSB9_9GAMM +---VLETVETIELSSSGTIGVSVLDTETNTTW-SYKGDHRFPMMSTFKTLACAQMLYNSS +NDLLDKDALTRITKESIIPWSPVTEKLIGETISTEKACEATMLMSDNTAANIVLAETGSP +KSLTLFLRLIGDDITRLDRIEPELNEAQKGDVRDTTTPNAMTNTLNELLFGQTLNTKDKR +TLKAWMVDNKVSDPLLRSILPAKWSIADRSGAGGFGSRGITAIVWSNKRAPIIISIYLTQ +TNLDMASRNQIIVEVGNAIFKEf +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C846877 +-----QSIEQIESRVSARIGIAVYDSATKQTW-SYKGNERFPMMSTFKTLACANLLYDFE +NEGLDLGLKVGIESDDLIVWSPVTKHLVGKDLSLENACTATMTMSDNTAANVVLTGVGGP +NGLTEFLRLAGDSNTRLDHMEPELNHARPGAVRDTTTPNSMVVTLNELVYGTTLSQESKL +KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE +TEFTIQERDKVINEIGQLIFDAy +>[subseq from] class A beta-lactamase n=1 Tax=Kocuria sp. Marseille-P3598 TaxID=1926282 RepID=UPI001301FA70 +---AAQKLRDLETRLDGRIGVHAINTGTQVRF-GYRSTERFLFCSVGKVLAVSAILHRAA +SDSTLLTRHIPIAADDILAYAPVTSQHVGGSMSVEDLCHAAITVSDNTAANLLVEVCGGP +SAVTEFVRGAGDVVTRVDRTEPTLNDA--DADLDTTTPSAFCTTLGNLALESVLTPEHRL +RLTTWLKANTTGADQIRAGVPDGVTVGDKTGAGSHGESNDVAVLWPTKGSPVILSIFTVS +SHQDTALQKEAIAEATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. LB126 TaxID=1983755 RepID=A0A2M8QV02_9SPHN +--------KEIEAETGGRLGVALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAVLTGAE +GGKFGLEGQISFTKADLLDYAPVVRKNAKRGMSMEELAAAAVEVSDNSAANLLLPMIGGP +EGLTRYVRAHGDMVTRLDRTEPALNENAEGDERDTTSPAAMAGLMGRLIFRD-LKPESAE +KLRGWLNASTTGGNRIKAGLPKDWISGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDAKAAEAAIAETARAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009C0A9B8 +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAALREAGSAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0008415508 +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAALREAGSAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BFDC36 +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAALREAGSAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Carnobacterium divergens TaxID=2748 RepID=Q4QXY0_CARDV +----SLNFEKLEKKYDATLGVYGLDTETNKVV-AYNEDQRFAFASTYKALAGGLVLNESS +--WDELNQTIMIKKEDLVTYSPITEKYVDIGMPLKELISAAIQYSDNTAGNFLFKQLGGP +KGFQTKLAELGDYTTDSSRFETELNEATPGDIRDTSTPKEIALDLKKLAIDHKLPTDKLE +FYKKQLIENTTGSKLIRAGIPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK +EQQESDYNDELIAETAKIVSDDf +>[subseq from] Beta-lactamase n=1 Tax=Carnobacterium divergens TaxID=2748 RepID=A0A4R9CQ36_CARDV +----SLNFEKLEKKYDATLGVYGLDTETNKVV-AYNEDQRFAFASTYKALAGGLVLNESS +--WDELNQTIMIKKEDLVTYSPITEKYVDIGMPLKELISAAIQYSDNTAGNFLFKQLGGP +KGFQTKLAELGDYTTDSSRFETELNEATPGDIRDTSTPKEIALDLKKLAIDHKLPTDKLE +FYKKQLIENTTGSKLIRAGIPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK +EQQESDYNDELIAETAKIVSDDf +>[subseq from] Beta-lactamase n=2 Tax=Acetobacter pasteurianus TaxID=438 RepID=S6D146_ACEPA +---------SYENATDGHIGVFAQNLATGQRL-TWRENERFVMCSTFKASLAALTLLRVD +QGKESLETFVPYTASDLGDYAPIAKANVGAGLSVRAMCEGAVEWSDNVCANLLLARVGGP +AVLTRFWRSLGDHETRLDDWEPALNRTPPGGRRNTTTPAAMAGILRQLVFGHVLSETSCS +LLTGWLKNCHTGGSRLRAGFPSTWAAGDKTGNNGKDAAGDIAVAWPKPEAPLIVCAYTRG +GHPDEKQFFEVFSEIGRIAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. WWJCD1 TaxID=2022519 RepID=UPI000B9A6465 +--SAEQNYLELEARDTARLGVNVLDLATGSTQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGKLQLTDTRTITAEDKVPESAVD-WAPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT +AALTDFARALGDTEFRLDRAEPELNTAIPGDPRDTTTPNSLAAGYRSLLDGDVLTEASRK +QLLEWMGDTETSTARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT +TSEDSPAMNPLVADATRAAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Carnobacterium divergens TaxID=2748 RepID=UPI001072C2B3 +-----LNFEKLEKKYDATLGVYGLDTETNKVV-AYNEDQRFAFASTYKALAGGLVLNESS +--WDELNQTIMIKKEDLVTYSPITEKYVDIGMPLKELISAAIQYSDNTAGNFLFKQLGGP +KGFQTKLAELGDYTTDSSRFETELNEATPGDIRDTSTPKEIALDLKKLAIDHKLPTDKLE +FYKKQLIENTTGSKLIRAGIPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK +EQQESDYNDELIAETAKIVSDDf +>[subseq from] Uncharacterized protein n=1 Tax=Brachybacterium sp. P6-10-X1 TaxID=1903186 RepID=A0A1P8NIG2_9MICO +-----AAFSALESRFSATLGLFALDTGSGTRI-EHRADERFGHASTLKALAAAAVLDSAP +----DLEIPIPVEAEDLVEYSPILQEQVGSTVTLREVADAAVRYSDNTAGNLLLAQLGGP +AGLEAALRAIGDRTTSVDRWEPELNEVSPGDVRDTSTPRALATSLQAFVLDGVLDADRSE +LLTEMLTTTTTGDTLIMAGALDGWEVGSKSGAAAYGTRNDLGIAWPSDRAPIVIAVMSHR +DAPDAEYDDRLVAEAAEVAFR-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Desertifilum sp. IPPAS B-1220 TaxID=1781255 RepID=UPI000903D0C4 +-nQLRDRIEQISRTAQGQVGVTATVLETGESV-TLNGEQQFPMQSVYKFPIAMAVLSQVD +RGTLNLDRKVRVETRDFALHSPIRDQHPQGVLTLAELLKYMVSESDNTACDVLLGLVGGP +EVVTQYLRDLGINDMVVANTEREIGQDNAVQYRNSATPDAAVALLSRLHEGQGLSASSQA +LLLQWMTETPTGLKRIKGLLPEGTVVAHKTGTSGTAATNDVGLVTLANGRHLAIAVFVSD +STADQATREAAIAQIARAAWDRw +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter tropicalis NBRC 101654 TaxID=749388 RepID=F7VAS9_9PROT +-------ISQYENETGGHVGFYAENTKTGATL-GWRTDERFVMCSTFKASLAACVLARVD +GGLDALERPLSYTAADIGDYAPVAKANLAKGMTIRELCAGAVEQSDNTCANLLLTHIGGP +SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGPVLSAPSRT +ILTDWLIRCRTGEHRLRAGFPSAWKIGDKTGNNGKDAAGDIAVIWPHPETSIVVCAYTRG +GHPTEQQLSSVFAGIGKLVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DCF6C98 +---VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD +RGEEKLDRRVFFGEKDLVMPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP +SALTAYLRSTGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIVLGSALSPTSRA +HLTEWMMASRDAAQRLRAGLPAGWRIANKPGTWEGISTNDIGVLFPPNRPPIVVAAYLGK +ARGSVAEQEAVLVDVARIVTR-- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio sp. A511 TaxID=2231647 RepID=UPI000E0C04BB +--SLEQSLSKIEQEIKGQVGVAVIDTQSLNQW-SYNGNQRFPMMSSFKTLACAKVLYDVE +QKKLSLNQKVDVPESGLVNWNPITENFVGSKMSLQSVCAAAMLMSDNYAANLALEQIGGP +SGLTAFLREIGDQKTRLDRYEPELNYVEKGAENDTTTPTDITQTVKRLLTGDVLSTSSKT +QLQFWMTNNMFSDSLARAVLPQGWLIADRSGGGVNGSRALTAMIWKSDRKPLFIGIFIAN +SSSTLPEINQVVADISQLIFTQy +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. 35-24ZXX TaxID=1545915 RepID=UPI0009DE8997 +--TFQTDLAAIEARSGGRLGVALLD-DAGRKVaGYRDDERFAMCSTFKLPLAAMVLEKAA +EGQWAMGDTLPVTDADMVAYAPYVEAQRAKSVTVEGAASAAVSLSDNAAANLLLDRLGGP +QGFTNWLKGKGDAVTRLDRREPELNENAVGDPRDTTTPSAIAETSRRLVLGKALPLGQQR +LLYRWMENTSTGLKRIRGGLPQGWSAGDKTGSCGN-AFNDVAVFTSEKGKRYTLAVYLDR +PTVKGDAASAIIADATRAVL--- +>[subseq from] Beta-lactamase n=1 Tax=Isoptericola sp. PW21 TaxID=2607479 RepID=A0A2W5WQ62_9MICO +--ATAEAFAALEERFDARLGVHALDTGDGTVI-EHRADERFAFASTMKALAGGLVLDRTG +--PDGWDEVVRYGAEDLVTYSPVTELHVDEGMTVLELVRASITVSDNTAANLLLDRLGGP +QSLEAALHELLSPDVSVDRAEPDLNDWAPGSTQDTATPAAMAAALRETALGDALRPEARA +ALRDALRDSTTGDALIRAGVPDGWVVGDKSGAGGHGTRNDIAVVERPDAAPLVLAVYSNR +RTPDGEADPALVAEATRVVVD-- +>[subseq from] Beta-lactamase n=2 Tax=Aquimonas voraii TaxID=265719 RepID=A0A1G6WVT0_9GAMM +--SAEARLRALESG-AARLGVCVLDTASGAHF-GHRLDEHFALCSTFKLALAAACLREAD +HGRLDLSEVLPYAESDLLEWAPVTREHLAEGLSIGRLAQAAQEISDGTAANLLVRRLGGP +AGVTARIRDMGDSVTRLDRYEPDLGLVLSADLRDTTTPVAMAQLVQRITTGDLLQPDSRD +QLLGWMRNTRTGLYRLRAGLPEDWLTGNKTGTGRTNKCNDIAITVPPGRSPVVIAAYYDS +GEQVERRHEAVLAEVARIAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Archangium gephyra TaxID=48 RepID=A0A2W5T5D6_9DELT +----HKALTALENSVKGRIGVFMLR--GEKTF-AYRATSRFTYCSSFKWILAAAVLEASQ +RGELLLSQRVKFTKKDLLGHSPIVEAHLDAGMTVAQLCEATVTVSDNAAANLLAPLVGGL +AGLSAFVKKLGDTTTRFDRMEPFLNSNEPGDKRDTTTPEAMTRLLHTALTSKHLTTDSQT +QLFMWMNAATTGLGRIRAAVPKDWSCGDKTGTSGNGALIDVAVLRPPSGEPIYVSVFLNA +RGIEMDTGSEVIAKAARIVLA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SAU5_KLEPN +----------------------------------------FPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIT--- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=A0A2G4WLK7_PHOLE +--NIDSAIKHAEQQLGAKVGVSVLNANGDSLY-GYNSEQRFPLMSTFKTLACAKLLHDNQ +ITKGMMDKTYPVTAEAILDYAPIFKDKVGTEVSLKDACFATMTTSDNSAANFVLAHIGGA +EGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA +QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG +TEASIPERDKEIAKIGNAIFERy +>[subseq from] Beta-lactamase n=1 Tax=Blastomonas fulva TaxID=1550728 RepID=A0A222X0U7_9SPHN +--AIARELAAIEARSGGRLGVALVGPDGHQLA-GHRADERFAMCSTFKLPLAAMVLENAH +KGRLSMADPLPVTDSDMVVYSPYVEAQRAKTVTVEGAASAAVSLSDNTAANLLLDRLGGP +QSFTAWLRGKRDSVTRLDRREPELNENALGDPRDTTTPAAMAETTRSLVVGNAMPVGQQR +LLYRWMENTSTGLKRIRGGLPQGWSAGDKTGSCGN-AFNDVAVFTAETGMRYTLAVYLDR +PAVKGDAASAIIADATRAVL--- +>[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea polychroma TaxID=46176 RepID=A0A438M5S0_9ACTN +--ELDKTLQELEKSYDGRIGAVGIDLGTGKTV-GYRAGERFPFNSMFKVFACAAVLRKAR +TDPGLMNRVVRWKPAEMAENSPETTEYTDTGMTPAQLCRAGITKSDGFAGNTLLKQIGGP +RGLTEFFRTIGDRTSRLDRTEPTLTEWKPGEERDTTTPAAAAQTFAKLTTGKTLHSRDRA +RLVGWLKASLTGANRIRAGLPKDWMVGDKTGTGGYGTANDVAIVWPPESAPIILSVFTNR +NLDDTPHDDKVIASTATALVK-- +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A2W4TAU9_9PROT +-------LSDLEARHGGRLGVAALDVASGRRV-LWRGQERFAFCSTFKAFLAAATLERVQ +HDEESLDRAVAVTRADIVPHAPVTEKAVGRTLTIRELMQATVEVSDNPAANILIREMGGI +AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPEQTLANIREMAFSERLTPENDA +LLHGWLTASPTGPNRIRAAAPEGWTVAHKTGTGANGTANDIAMLTPLSGSPVIVAAYFTG +ATATDDQRDAVIAEATRRALK-- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderiaceae TaxID=119060 RepID=A0A1G5MDP0_BURVI +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMSSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=A0A2T3PZV0_PHOPO +--QIEPALTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDDTTRLDRIEPNVNNVSATELRDTTTPIAMNSTLYSLLYGHALSETART +QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMADLNAAIAKIGQLIFTH- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. Ae707_Ps1 TaxID=1885572 RepID=A0A1Q8KIE6_9PSEU +--------DGVEREFGRRIGVHVLDSGTGATA-GHRDGERFLMCSVVKALMAGFVLHRSV +ADPALLDRPVRWGRADLLEYAPVTSRHVDSGLSVAQLCEAAVTVSDNTAHNLLLREVGSP +ADLTAWLRSTGDGVTRADRYETALNDV--DGDRDTSTPAALAATLRALTTGDVLPSAQRD +RLVGWLRANTTGDEQIRAGVPDGWQVGDKTGSGPLGEKNDAGVLFPPQGAPVLLTVFTVP +ADPDDDRGAAAVASATRAA---- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhodococcus TaxID=192944 RepID=UPI000B9B2234 +--SAEQAYLELEARDTARLGVSVLDLETGSTQ-SYRGGERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTITAEDKVPESAVD-WDPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPGDPRDTTTPDSLAAGYRTLLDGDVLTESSRK +QLLAWMGDTETSAARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT +TSEDSPAMNPLVADATRAAVQQ- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000CDAEF51 +-------------------------------------------------------TARFD +AGAEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter sp. SVU/SVIMS1 TaxID=1476168 RepID=W8SQG3_9GAMM +------------------------------------------MCSTSMVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 14-2496-1d TaxID=2023146 RepID=UPI000B9B17AB +--SAEQAYLELEARDTARLGVSVLDLETGSTQ-SYRGGERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLAVAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPGDPRDTTTPDSLAAGYRTLLDGDVLTEASRK +QLLEWMGDTETSAARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT +TSEDSPAMNPLVADATRAAVQQ- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium llatzerense TaxID=280871 RepID=UPI0008DDFF39 +------RFEELEDRYQALIGVYAVDLESLATV-EHRADERFSICSTFKAYAAARILQMDK +AGQANLDAMVPITAADIVVNSPVLSPAVGTRMELREICAAALTQSDNAAGNIMLRTIGGP +SALTAFARSIGDSQTRLDRWEPDLNDAAPGDLRDTTTPRVLCGGYRAILVGDALPGAGQF +QLKRWMTETTTSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGLLIGPKRERVMLTVLIRT +RTRDAGPFNEAVAESVRSV---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0005F002E6 +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLVRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. HH130629-09 TaxID=1641402 RepID=A0A0M4Q4B5_9PSEU +-------MADVERTYARTIGVHVLDTGTGRSA-GHRDGDRFLMCSVIKALMAGFTLHRSL +SDPGLLDRPVRYGRADLLEYAPVTTRNLATGMTVAQLCEAAVTVSDNTAHNLLLREVGSP +AELTAWLRTTGDTVTRSDRAETALNDR--DGERDTSTPAALASTLRTLVLGDALPAPQRD +RLAGWLRANTTGDRQIRAAVPAGWGVGDKTGSGPLGERNDSGVLYPPDGAPLVLTVFTVP +ADADEQRGEDAVAAAARAAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2W6SHF8_9SPHN +--------KEIEAETGGRLGVALVDSKGALLL-GFNRDERYPMCSTFKAPLAAAVLVGAE +GGKFGLEGTIPFGKDDLIDNAPVVKKNLKRGMSMEELAQAAVEVSDNSAANLLLPMLGGP +EGLTAFMRAHGDTVSRLDRTEPALNENVEGDPRDTTSPAAMAGLMARLIFND-LKPDSAA +RLRNWLNASSTGDHRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPGGDEYVLAIYLDR +PTVDAKKAEAAIAETARAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 06-469-3-2 TaxID=2022510 RepID=A0A259Y4U0_9NOCA +--SAEQAYLELEARDTARLGVSVLDLETGSTQ-SYRGGERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLAVAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPGDPRDTTTPDSLAAGYRTLLDGDVLTEASRK +QLLEWMGDTETSAARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT +TSEDSPAMNPLVADATRAAVQQ- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus TaxID=1827 RepID=UPI00050CD281 +--SAEQAYLELEARDTARLGVSVLDLETGSTQ-SYRGGERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLAVAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPGDPRDTTTPDSLAAGYRTLLDGDVLTEASRK +QLLEWMGDTETSAARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT +TSEDSPAMNPLVADATRAAVQQ- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=UPI000D16CA3B +--QIEPALTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAMNSTLYSLLYGHALSETART +QLKQWMMDNKVSDPLLRAALPASWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMADLNAAIAKIGQLIFTH- +>[subseq from] Beta-lactamase n=2 Tax=Listeriaceae TaxID=186820 RepID=A0A099W984_9LIST +--QVKAALEKLEKKYGATLGVYGMDMGGKQTI-SFNAEERFAYASTFKAIAGGILLKNLT +--DEQLNKRFTFSKEDLVDHSPITEKHVDSGMTMKELINASMTYSDNTAANLTLQQLGGP +KGFEKELVKIGDKTMKPVRFEPELNDAVPGDIRDTTTPEAMAKTFAYLLTEGNLPADRLA +YFKQTLIDNTTGATLIRAGVPAGYIVGDRTGAGSYGTRNAIAMIYPKDKKPLVWVIYSKK +TGKDDEYNDQLIADAAKVLSDYy +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 06-418-5 TaxID=2022507 RepID=UPI000B9ACBF7 +--SAEQAYLELEARDTARLGVSVLDLETGSTQ-SYRGGERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLAVAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPGDPRDTTTPDSLAAGYRTLLDGDVLTEASRK +QLLEWMGDTETSAARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT +TSEDSPAMNPLVADATRAAVQQ- +>[subseq from] Class A beta-lactamase n=1 Tax=Shewanella sp. Pdp11 TaxID=2059264 RepID=A0A2K8ZPL0_9GAMM +-----QTVNEFER-QGWNIGVSVIENSSNNVY-LINGDERFSTNSTIKALACAIVLSEVD +KNAVSLDDAMMINEQDVVSHSPVMKEFIGKKVTLADACKATMTYSDNTAANFAIKKSGGP +EGITSFLRSMGDDITRADRYEPDLNTNPEGDLRDTSTANAMAANFNKLLLGNILSTQSKE +QLKDWMMGNKVADNMLRLVLPTGWEIADRTGANSYGARGIISMVWSESQQPLIISIYIKK +ENTAIEEREKVISEIGRVIFTEy +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. C100 TaxID=1207055 RepID=W1S8K9_9SPHN +--------KEIEEETGGRLGVALVDRQGALIL-GFNRDERFAMCSTFKAPLAAAVLTGAE +GGKFGLEGQIPFGSDDILDYAPVVKKNKKRGMSMSELAQAAVEVSDNSAANLLLPMLGGP +EGLTAFIRAHGDSVTRLDRNEPTLNENAQGDPRDTTTPAAMAGLMGRLFFRDM-SAQSAD +TLRAWFNASSTGDKRIKAGLPEGWTSGSKTGTCGN-AYNDVALVKSPAGDEYILAIYLDR +PTVDAKKAEAAIAETARAALN-- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=UPI000D170D3D +--NIDSAIKQAEQQLGAKVGVSVLNGKGDALY-GYNSDQRFPLMSTFKTLACAKLLHDNQ +ITKGMMDKTYPVAAEAILDYAPIFKDKIGTEVSLKEACFDTMTTSDNSAANFVLAQIGGA +AGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA +QLTQWMKSNKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG +TQASIPERDKAIAKIGSAIFQQy +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium damselae subsp. damselae TaxID=85581 RepID=A0A0D8LF53_PHODD +---VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ +INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP +VGVTTFLIDSGDSVTRLDRIEPLLNEATPGDKRDTTTAYAMNKTITNLVLGNALNESSKQ +QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG +TKASIPERDEEIAQIGQAILQQf +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Bacteria TaxID=2 RepID=W1W6T5_9STAP +------------------------------------------------------------ +------------------------------------------------ANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKNGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009C0BD3D +-----SPLAEIERRNGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTENDLIFTSPVTKANVAHGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. HS-D2 TaxID=1384636 RepID=UPI0007D94ADB +---VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA +EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP +GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR +TLLGWMRATTTSDTRIRGGLPPGWTSADKTDGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacterales bacterium RIFCSPHIGHO2_01_FULL_67_30 TaxID=1797584 RepID=A0A1F8IBJ2_9PROT +-------LSDLEARYGGRLGVAALDVASGRRV-LWRGQERFAFCSTFKAFLAAATLERVQ +RDEESLDRAVAVTRADIVPHAPVTEKAVGRTLTIRELMQATVEVSDNPAANILIREMGGI +AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPEQTLANIREMAFSERLTPENDA +LLHGWLTASPTGPNRIKAAAPEGWTVAHKTGTGANGTANDIAMLTPLSGSPVIVAAYFTG +ATATDDQRDAVIAEATRRALK-- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=UPI0009BF8F7A +--NIDSAIKHAEQQLGAKVGVSVLNANGDSLY-GYNSDQRFPLMSTFKTLACAKLLHDNQ +ITQGMMDKTYPVTANAILDYAPVFKDKIGTEVSLKDACFATMTTSDNSAANFVLAHIGGA +EGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA +QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG +TEASIPERDKEIAKIGNAIFERy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BFB999 +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A4JN42_BURVG +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] Beta-lactamase n=2 Tax=Caulobacterales TaxID=204458 RepID=A0A069J1Z2_9CAUL +-------LNDLEARHGGRLGVAALDVASGRRV-LWRGQERFAFCSTFKAFLAAATLERVQ +RDEESLDRAVAVTRADIVPHAPVTEKAVGRTLTIRELMQATVEVSDNPAANILIREMGGI +AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPEQTLANIREMAFSERLTPENDA +LLHGWLTASPTGPNRIKAAAPEGWTVAHKTGTGANGTANDIAMLTPLSGSPVIVAAYFTG +ATATDDQRDAVIAEATRRALK-- +>[subseq from] class A beta-lactamase n=1 Tax=Micrococcales TaxID=85006 RepID=UPI00065FBA9A +---AAQKLRDLETRLDGRIGVHAINTGTQVRF-GYRSTERFLFCSVGKVLAVSAILHRAA +SDSTLLTRHIPIAADDILAYAPVTSQHVGGSMSVEDLCHAAITVSDNTAANLLVEVCGGP +GAVTEFVRGAGDVVTRVDRTEPTLNDA--DADLDTTTPSAFCTTLGNLALESVLTPEHRL +RLTTWLKANTTGADQIRAGVPDGVTVGDKTGAGSHGESNDVAVLWPTKGSPVILSIFTVS +SHQDTALQKEAIAEATRIVT--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0N9HKW2_9BACT +-eLLRTKIYGIIEKANGRVGAAIINLETLDTL-TFNDDHHYPMQSVFKFPLALAVLNEVD +KGNLSLNQKVHLKKEDLLPWSPLREKYPDGNITLSELLTYTVSISDNNGCDVLFRLVGGT +EKVNQFVHSLGISEMEIAANEEEMHREWDVQFQNWTTPSAMGQLLYKFVDDSILSNDSKD +FLWNIMVSTVTGPRRIKGQLPDGTIVAHKTGSSGAAATNDVGIVTLPNGKQYIIVVFVSD +SPDDENAREEIIAGIAKAAWDAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00062128CE +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Asticcacaulis tiandongensis TaxID=2565365 RepID=UPI001126DB6E +------EISKIEEETGLTIGVHIAG---RSLFaGYRDYHRFALCSTFKWMLAATVLREVQ +QNRLGLDQMISFGKADLVPHAPVTEKYLADGLTVEQLCHAILVHSDNVAANLLLRQIGGP +EAVTQFCRDNGDTVTRLDRYETELNSNLSGDERDTTTPEAMSQLMQRVFTGESLSRSHTR +RIENWMRESQTGKAMIHAGAPENAVVADKTGRGANGAVNDVAIIRMPKYGPLFLSIYTTG +GTLTAEQHNAVIANLTTYIFK-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium tokaiense TaxID=39695 RepID=A0A378TN43_9MYCO +---------EAERRHQARIGLYALDLKTHKTI-AHRNHERFAMCSSVKTYVAARVLQKAE +RGELALTDSVVVHGADIVSNSPVTETWVGRSIPVADLCAAALQKSDNAATNYLLKAVGGP +PAITEFARSISDNETRLDRWETELNSAIPGDVRDTSTPQALGDGNRALLEGTALTLESRR +QLIEWMVANTT--SSLRPGMPPEWILADKTGGGGYGSTNDVGLGFGPGGQQVVLSVMMRS +ATPNADGFRPVMAEIAAVVMS-- +>[subseq from] Uncharacterized protein n=1 Tax=Frigoribacterium sp. Leaf186 TaxID=1736293 RepID=A0A0Q5S2G7_9MICO +--EVEAALVDLESRYDARVGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLDATD +--DADLDRVVTWTQADVDAYSPLTSQHVADGLPLRQLAEAAVRQSDNTALNLVLAELGGP +AGLDAALAAQGDDVTDVVHTEPELNTPTPGSTADTTTPAAFTATLARITDGDWLAADDRA +TVRDWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVTPPAGDPVVISVLTTR +NDPAATYDDALVAEAARIAL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Kocuria sp. HSID16901 TaxID=2419505 RepID=A0A3S1AVA0_9MICC +---AAQKLRDLETRLDGRIGVHAINTGTQVRF-GYRSTERFLFCSVGKVLAVSAILHRAA +SDSTLLTRHIPIAADDILAYAPVTSQHVGGSMSVEDLCHAAITVSDNTAANLLVEVCGGP +GAVTEFVRGAGDVVTRVDRTEPTLNDA--DADLDTTTPSAFCTTLGNLALESVLTPEHRL +RLTTWLKANTTGADQIRAGVPDGVTVGDKTGAGSHGESNDVAVLWPTKGSPVILSIFTVS +SHQDTALQKEAIAEATRIVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas sp. SYSUP0004 TaxID=2494735 RepID=UPI0010101757 +----AAAFAGLESATGARLGVWALDTATGRTV-EHRADERFGLASTHKVLSVAALLAALR +--PGDLDAVVHWPEGDVVAHSPVTAGRGASGLTWREVAAAALVESDNTAANLVLERVGGP +AGLTGSLRAWGDTVTRSDRTEPALNEVAPGDERDTTTPRALATDVHALLLGDALTDEDRG +LLLGWMRASTTGTGLVRAGVPDGWVVADRSGTGSHGARNDVAVVHPPGGAPVVLAVLTRH +DDPDALPDDDLLARATEVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=UPI0005D3DEE0 +---VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ +INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP +VGVTTFLIDSGDSVTRLDRIEPLLNEATPGDKRDTTTAYAMNKTITNLVLGNALNESSKQ +QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG +TKASIPERDEEIAQIGQAILQQf +>[subseq from] Class A beta-lactamase n=1 Tax=Roseococcus sp. SYP-B2431 TaxID=2496640 RepID=A0A4R0YGC1_9PROT +---AEAPLAALERREGGRLHVFALDTGSGRSL-AHRADGRVLMCSTFKALLGAAVLARVD +AGQESLDRRVAIRGEDLLAYAPVARAHAGAGASVAVLAEGMVGLSDNTAANLLLPGVGGP +AGLTRWLRGIGDPLTRLDRDEPGLNR--PSGEMDTSTPRQMAMTLRRILLGEVLAPASRE +RLEGWMAASPTGRARLRAGFPPGWPVADKTGTGES-WANVIALVRPPGRAPAVVASFYDL +ANAAGAKRDSVHREVGRIV---- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonadales bacterium RIFCSPLOWO2_12_FULL_63_15 TaxID=1802170 RepID=A0A1G3KG28_9SPHN +--------KEIEQETGGRLGVALVDKQGALLL-GFNRDEPFAMCSTFKAPLAAAVLIGAE +GGKFGLEGEISFSKDDILDYAPVVKANRKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP +QGLTAFMRAHGDSVTRLDRNEPELNENAEGDPRDTTTPAAMAGLMGRLLFRDM-QGESAE +RLRGWLNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGDEYILAVYLDR +PTVDAKKAEAAIAETARAALE-- +>[subseq from] Beta-lactamase GES10 n=1 Tax=uncultured bacterium TaxID=77133 RepID=C6GC02_9BACT +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRTAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLCDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. RAC03 TaxID=1843368 RepID=A0A1B3MS40_9SPHN +--------KEIEQETGGRLGVALVDKQGALLL-GFNRDEPFAMCSTFKAPLAAAVLIGAE +GGKFGLEGEISFSKDDILDYAPVVKANRKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP +QGLTAFMRAHGDSVTRLDRNEPDLNENAEGDPRDTTTPAAMAGLMGRLLFRDM-QGESAD +RLRGWLNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGDEYILAVYLDR +PTVDAKKAEAAIAETARAALE-- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. BAL3 TaxID=391600 RepID=B4WBN9_9CAUL +-------LSDLEARHGGRLGVAALDVASGRRV-LWRGQERFAFCSTFKAFLAAATLERVQ +RDEESLDRAVAVTRADIVPHAPVTEKAVGRTLTIRELMQATVEVSDNPAANILIREMGGI +AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPEQTLANIREMAFSERLTPENDA +LLHGWLTASPTGPNRIKAAAPEGWTVAHKTGTGANGTANDIAMLTPLSGSPVIVAAYFTG +ATATDDQRDAVIAEATRRALK-- +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium sp. ba1 TaxID=1522072 RepID=A0A087NH71_9SPHN +--------KEIEQETGGRLGVALVDKQGALLL-GFNRDEPFAMCSTFKAPLAAAVLIGAE +GGKFGLEGEISFSKDDILDYAPVVKANRKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP +QGLTAFMRAHGDSVTRLDRNEPDLNENTEGDPRDTTTPAAMAGLMGRLLFRDM-QGESAE +RLRGWLNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGDEYILAIYLDR +PTVDAKKAEAAIAETARAALE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Frigoribacterium sp. PhB24 TaxID=2485204 RepID=A0A3N2HKE9_9MICO +--EVEAALTDLETRYDARIGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLDATD +--DAALDRVVTWTQADVDAYSPLTSEHVTDGLPLRQLAEAAVRQSDNTALNLVLTELGGP +AGLDAALAAQGDDVTDVVHSEPELNTLTPGSTADTTTPAAFTATLARVTDGDWLEADDRA +TLLEWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVVPPSGDPVVISVLTTR +NDPAAKYDDALVAEAARIAL--- +>[subseq from] Uncharacterized protein n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=A0A2T3JWG7_PHOPO +--QIAPELTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAINSTLYSLLYGHALSETART +QLKQWMMDNKVSDPLLRAALPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMADLNAAIAKIGQLIFTH- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium tokaiense TaxID=39695 RepID=UPI000E1BFB59 +---------EAERRHQARIGLYALDLKTHKTI-AHRNHERFAMCSSVKTYVAARVLQKAE +RGELALTDSVVVHGADIVSNSPVTETWVGRSIPVADLCAAALQKSDNAATNYLLKAVGGP +PAITEFARSISDNETRLDRWETELNSAIPGDVRDTSTPQALGDGNRALLEGTALTLESRR +QLIEWMVANTT--SSLRPGMPPEWILADKTGGGGYGSTNDVGLGFGPGGQQVVLSVMMRS +ATPNADGFRPVMAEIAAVVMS-- +>[subseq from] class A beta-lactamase n=1 Tax=Diaphorobacter sp. HDW4A TaxID=2714924 RepID=UPI0014087F2D +--SFQQRLKVLEARSGGRLGLSVQVLGGQNSI-GYREDEMFPMCSTFKLLLAARILQLSQ +LGEFPLEQSLLYEKKELVAYSPETEKHADVDMTIRALCEAAVVLSDNTAANLLLNLQGGP +AGLTRWLRTVGDMRTRLDRIETDLNTAIAGDPRDTTTPRAMGKTALALLTDKLLTPGSQK +QLRDWLLASRTGDKRLRTGMPSDWKIGGKTGSGDNGTANEVSIVWSAQGAPMIVSAYLTG +AMVESEGRDAILAEVGRVVTDWy +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI0014287AA4 +-aQLTQTIKNIENDWKGRIGVYAYDTEGDFTF-GYRDKERFPLCSSFKSFLSAAILAKSQ +ENLLNINTLIDFSDRELEYWSPITKENQKYGMTIGKLAQAALQYSDNGATNILLESIGGP +KGMNNFMQSIGDNNFRLDRWELELNTAIPGDIRDTSTPKSMATSLGNLSFGDVLNDTNRE +LFNNWLIGNTTGDNRIRAAADKSWIVGDKTGSCGYGAASDIAVIWREKSSPLVMAIYTHK +TDPTAKHNDKVIAEVADKTF--- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A521MIJ7_9CAUL +-------LSDLEARHGGRLGVAALDVASGRRV-LWRGQERFAFCSTFKAFLAAATLERVQ +RDEESLDRAVAVTRADIVPHAPVTEKAVGRTLTIRELMQATVEVSDNPAANILIREMGGI +AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPEQTLANIREMAFSERLTPENDA +LLHGWLTASPTGPNRIKAAAPEGWTVAHKTGTGANGTANDIAMLTPLSGSPVIVAAYFTG +ATATDDQRDAVIAEATRRALK-- +>[subseq from] Beta-lactamase PSE-4 n=1 Tax=Photobacterium toruni TaxID=1935446 RepID=A0A1T4URL0_9GAMM +--QLSLELTNIEQQLGGNVAVAIYNANTNKSW-SYHGEQRVPMMSTFKTLACADLLHQAD +AQLVSVNQPIMIKQSDILSYAPVTKNHVGTSMTLAQLCHATMLTSDNTAANLVLNNIGGP +QSVTQFIRTLDDKTTRLDRIEPNVNNVSATEQRDTTTPIAINSTLYRLLYGNALSEQARI +QLKHWMMENKVSKPLLRAALPAGWHIADRAGYDTYGSRGITAAVWQQDKQPIMISIYVTQ +TGKPITELNAAIAKIGQLIFTH- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. BCC1885 TaxID=2562669 RepID=UPI001183CF43 +----DSPLADIERQHGGRLGVFAIDTASSRTL-AYRADERFLMCSTFKGLLAAQVLARVD +AGKERLDRLVNYTGKDLIFTSPVTKANVAQGMSVGALCQAIVEVSDNTAAILLMKSVGGP +AALTQFVRSLDDTVTRSDRYEPASNQY--SGVLDTTSPKAIIGAVSRILLGDVLSAQSRT +QLESWMIACKPGLNRLRASLPADWRAGDRPGTSIEAETNDYAIVRPPGRAPLLVAAYYDA +PHVSMDSREAVLREVGTVFV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A075M4I6_ECOLX +------------------------------------------MCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLIL------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=UPI0009BC0042 +---VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ +INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP +VGVTTFLIDSGDSVTRLDRIEPLLNEATPGDKRDTTTAYAMNKTITNLVLGNALNESSKQ +QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG +TKASIPERDEEIAQIGQAILQQf +>[subseq from] class A beta-lactamase n=1 Tax=Cellulosimicrobium cellulans TaxID=1710 RepID=UPI0009F43C1E +--DVADELAALEAAYDARVGVHAVDTATGDHV-EHRADERFAYASTIKALAAGVLLQGQP +--VSALDETLPVTAEDVEGWSPVTGSRVGTAMTVRELGAAAVSQSDNGAFNVLLRRIGGP +EALQAALVEAGDTTTLVDAWEPELNHFTPGDPARTSTPRALADGVAAFALGDALDPAVRD +VYVSWLTGSTTGDGTIRAGAPEGWTVGSKTGTAGYGSRNDVAVVWPPDGAPIVLAVLTDR +AGMDDEPDDALLADVTAVVLGAf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium fuliginis ATCC 27551 TaxID=1208342 RepID=A0A5B8CFM9_SPHSA +--------KEIESATGGRLGVALVDSKGVLML-GFNRDERFAMCSTFKAPLAAAVLTGAE +GGKFGLEGQISFTRSDLLDYAPVVRKNAKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP +EGLTRFIRAHGDMVTRLDRNEPSLNENVEGDERDTTSPAAMAGLMGRLIFRDL-APESAE +KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTIDARAAEAAIAETARAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. BCC1886 TaxID=2562670 RepID=UPI001182A047 +----DLRLSDIERRNGGRLGVFAIDTGSGRTL-SHRAEERFLMCSTFKGLLVAQILARVD +SGEEQLDRRVHYTEKDLIFTSPVTKANVARGLSIDALCQATLVESDNTAAILLMRSAGGP +AALTRFVRGLGDPVTRSDRYEPESNRY--RGVLDTTTPKAMTITARHLLLGDALSASSRA +QLERGMIDCKPGLNRIRAVLPSGWQAADRPGTSVESETNDYALVRPPGRAPLIVAVYYDA +PGVSMDEREAVLREAGMAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 06-412-2C TaxID=2022487 RepID=A0A260AA52_9NOCA +--------LELEARDTARLGVNVLDFATGSTQ-SYRGDERFAFCSTFKVYAVGAVLTAVD +AGKLQLTDTRTITAEDKVPESAVD-WAPGSVVTIADLAAAALAKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSLAAGYRTLLDGDVLTEASRK +QLLEWMGDTETSTARFRAGIAPQWTSADKTGTGSYGVSNDAGLLFGPDGQRILLVVLSAT +TSEDSPAMNPLVADATRAAVQQ- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=UPI000D160537 +--NIDSAIKHAEQQLGAKVGVSVLNANGDSLY-GYNSEQRFPLMSTFKTLACAKLLHDNQ +ITKGMMDKTYPVSAEAILDYAPIFKDKVGTEVSLKDACFATMTTSDNSAANFVLAHIGGA +EGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA +QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG +TEASIPERDKEIAKIGNAIFERy +>[subseq from] Beta-lactamase class A n=2 Tax=Frondihabitans australicus TaxID=386892 RepID=A0A495IIB4_9MICO +--ALRAALASLEMRDHERLGVSVAVAGTDEHF-SYRGGERFALDSTSKLFTATLLLRDDS +--DAQLAQTIHYTAADLQSYSPITSQHVDTGMSLRDVIAAALQYSDNTAANLMFEQLGGP +TAVERDVRALGDGVTTFDRIEPDLNTAVPGDRRDTTTPDEMAADVGRFTLGATLRPARRS +LLVDLMRGNTTGDADVRAVVPSGWIVADKTGSGGYATANDVALVTRPGAAPILIAVYTSG +TSADATTPDGIVADVARAALD-- +>[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus epidermidis TaxID=1282 RepID=A0A6A1Z9W6_STAEP +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVGYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYETELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKTGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Georgenia sp. ZLJ0321 TaxID=2483797 RepID=UPI000FDB9B7D +--DVTADLDALETEFDARVGVSALDTETGRSV-EYRAQERFGYASTLKVFAAAELLRQVP +--PGEWEARVVWTQEEVDAYSPVTSEHVDGGLSLAELAEAAVRESDNTAMNLVLDRIGGP +AGLDAGLAALGDETTDVVNNEPALNEIDAGDTRDTTTPAAFTADLHALLQPQNLAPDDRA +TLLDWMSGNPTGDALIRAGAPAEWVVQDKSGGAG-GIRNDIALVTPPGRAPIVITVMTEK +NDPAAEYEDELVARVAEVVIT-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB47DC +---VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD +RGEEKLDRRVFFGEKDLVMPFKATKPHLTDGMTVEQLCEAAAIVSDSTAANLLMASFGGP +FALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIVLGSALSPTSRA +HLTEWMMASRDAAQRLRAGLPAGWRIANKPGTWEGISTNDIGVLFPPNRPPIVVAAYLGK +ARGSVAEQEAVLVDVARIVTR-- +>[subseq from] class A beta-lactamase SGM-2 n=1 Tax=Sphingobium japonicum TaxID=332056 RepID=UPI00031FB5C4 +--------KEIETESGGRLGVALVDGKGALIL-GFNRDERFAMCSTFKAPLAAAVLAGAE +GGKFGLEGQISFAKADLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP +EGLTRFIRAHGDMVTRLDRNEPSLNENAEGDERDTTSPAAMAGLMGRLIFRDL-APESAG +KLRGWLNASTTGANRIKAGLPKGWISGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDAKAAEAAIAETARAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=UPI0011A5CEB6 +---VDERLKEIEDRYAVRLGVVAQSPVTGRVH-THRADERFAICSPFKVYAAAAILRLEA +EGTLRLDETLPIDPDDIVVNSPVTSEHQGRVLPLDRLCEAALTRSDNTAGNLMLQRIGGP +EAVTAFARSVGDGTTRLDRWEPELNEAARGDQRDTTTAAGLSRGFGEVLLGSGLPAPQQR +TLLGWMRATTTSGTRIRGGLPSGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLVILSDS +TTGDPD----------------- +>[subseq from] Beta-lactamase n=1 Tax=Gluconacetobacter entanii TaxID=108528 RepID=A0A318Q1G2_9PROT +-------LSDYEHATGGHVGVYAHNIATGRRL-LWRANERFVMCSTFKASLAACVLSHVD +QGRDGLDHIIPLTAADIQDYAPVAKAALAQGLSVGDMCEGAVEQSDNSCATLLLSRIGGP +SALTAFWRAMGDTTTRLDDPEPYLNRTPAGGVRDTTTPASMAAIIQKLVLGTVLSAPSRA +LLTRWLVGCQTGKNRLRAGLPANWVVGDKTGNNARDAAGDIAVAWPRPDTPIVMCVYTRG +GTPTEQQFAAVFSGIGRLVAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium japonicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S) TaxID=452662 RepID=D4Z324_SPHJU +--------KEIETESGGRLGVALVDGKGALIL-GFNRDERFAMCSTFKAPLAAAVLAGAE +GGKFGLEGQISFAKADLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP +EGLTRFIRAHGDMVTRLDRNEPSLNENAEGDERDTTSPAAMAGLMGRLIFRDL-APESAG +KLRGWLNASTTGANRIKAGLPKGWISGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDAKAAEAAIAETARAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Sandarakinorhabdus sp. NM-18 TaxID=2675220 RepID=UPI0012E2B6C8 +---LRRAIPLIERSAGGPIGIALLDTSSGARF-SHRAQQRFPLCSTFKLLLAARLLHGAD +RKLWSMTDRLPIRREDMLFNAPFTEKRIGGTASLLELAEAMTVLSDNPAANLGLAHVGGP +AALTRWLGAIGDSVTRLDRNEPEMNNETPGDPRDTTTPAAMLATCRTLVTGRILSPAARA +QLFAWMQASKTADTMIRAALPQGWQEANKTGAGSWHARNIVSVITPPGRKPIWVAAYLFA +ARSELAERNRQFVPLGRAIVE-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonadales bacterium 28-64-96 TaxID=1970591 RepID=A0A258VBI7_9SPHN +--ALCRAITAVERSAGGPIGISLLDTHTGERF-GHRANDRFPLCSTFKLLLAARLLHGAD +KGQWAMSERLPVTKADMLFNAPFTEKRIGGSASLLELAEAMAVVSDNPAANIGLARVGGP +AALTRWLRTIGDQTTRLDRNEPEMNNETPGDPRDTTTPAAMLATSRVLVEGRILSPAARR +TLFGWMQASKTADTMIRAALPPGWQEANKTGAGSWRARNIVSVITPPGRKSIWVAAYLFA +GKSELAERNRQFVPLGRAIVE-- +>[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=4 Tax=Bacteria TaxID=2 RepID=A0A6D1U1F7_STAEP +--SHAQELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVGYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQHLKELGDKVTNPVRYETELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKTGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Aliivibrio wodanis TaxID=80852 RepID=A0A090KI17_9GAMM +---VLETVETIELSRSGTIGVSVLDTETNTTW-SYKGDHRFPMMSTFKTLACAQMLYNSS +NDLLDKDALTRITKESIIPWSPVTEKLIGETISTEKACEATMLMSDNTAANIVLAETGSP +KSLTLFLRLIGDDITRLDRIEPELNEAQKGDVRDTTTPNAMTNTLNELLFGQTLNTKDKR +TLKAWMVDNKVSDPLLRSILPAKWSIADRSGAGGFGSRGITAIVWSNKRAPIIISIYLTQ +TNLDMASRNQIIVEVGNAIFKEf +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. shizuoka-1 TaxID=2039281 RepID=A0A2C9T155_9MYCO +---IDQRIAALERRHNAFAGVYGQNLDSGQTV-TNRADDMFAMCSTFKAYLAARVLQKAQ +AGELRLTDTALVDPELLRANSPRTEPHVGTPMALSELCAAALQVSDNTAANVLLRVIGGP +PEITAFARSIGDERSRLDRWETELNSALPGDPRDTSTPSALGGGVRALLTGTVLDEPHRR +QLEDWMRANTT--SSMRAGLQPGWTTADKTGSGDFASTNDVGLLFGPAGERILLAIMTRT +QSDDAPGLRPLIGELTALVV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A2W6XEU7_9CAUL +-------LADLEARHGGRLGVAALDVGSQRRV-SWRGQERFPFCSTFKAFLAVAVLERVQ +RGEEQLDRAVPVVRADMIPHAPVTEKAIGRTLTIRELMQAAVEVSDNPAANILIREMGGI +AVWRAWWPTFGDITTLISRLEPDLNTALPDDPRDTCLPDQTLANIRELAFSDRLTPEHDQ +MIQGWLTASPTGPNRIKAGAPQGWTVAHKTGTGVNGTANDIGVAFPVSGSPVVLATYFTG +ATASDDQRDAVIAEATRRVFK-- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A103I4F7_BURVI +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTENDLIFTSPVTKANVAHGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSLDAREAVLREAGSAFV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus rhodochrous J45 TaxID=935266 RepID=A0A562D6J2_RHORH +---VDERLKEIEDRYAVRLGVVAQSPVTGRVH-THRADERFAICSPFKVYAAAAILRLEA +EGTLRLDETLPIDPDDIVVNSPVTSEHQGRVLPLDRLCEAALTRSDNTAGNLMLQRIGGP +EAVTAFARSVGDGTTRLDRWEPELNEAARGDQRDTTTAAGLSRGFGEVLLGSGLPAPQQR +TLLGWMRATTTSGTRIRGGLPSGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLVILSDS +TTGDPD----------------- +>[subseq from] class A beta-lactamase n=2 Tax=Vibrio cholerae TaxID=666 RepID=UPI000E6B89A0 +-dNLTQAVTKIESDWQGRIGVFAYEVNGDFRF-GYREAERFPFCSSFKAFVAAAILTQSQ +NELIDLNNIVDFKNRELEFWSPITEKYRYDGMTIGQLAKASLQYSDNGATNILLERIGGP +EQMTYFMRNLGDSVFRLDRWELDLNTAIPGDNRDTSTPYAMASTLGKLAFSDTLDLAHRK +IFHNWLMGNTTGDKRIRASVPNTWIVGDKTGTCGYAAANDIAVIWREQLSPLVIAIYTHK +LHATDKHSDQVIASVTSEIVKH- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium anyangense TaxID=1431246 RepID=UPI00138D8B75 +---LDERIGMLERRHNAVVGVYGANLDAKYTV-AHRDNDMFAMCSTFKAYLSARVLQKAQ +RGELRITDTLVVDPTAVLPNSPITGPKAGSALSLAQLCQAALQRSDNTAANMLLTVIGGP +QEITAFARSIGDERTRLDRWETELNSALPGDPRDTSTPRALGGGFRAILTGDVLDEVHRR +QLEDWMRGNTT--SSMRAGLQPGWATADKTGSGAFASTNDVGIVFGPNGERILLAVMTRT +RSADAEALRPLIAEVTTLVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio sp. OCN044 TaxID=2695891 RepID=UPI00136845A6 +--SLEQSLSKIEQEIKGQVGVAVIDTQSHNQW-SYNGNQRFPMMSSFKTLACAKLLYDVE +QKKLTLNQKIDVPESGLVNWNPITENFVGSKMSLQSVCAATMLMSDNYAANLALQQIGGP +SGLTAFLREIGDQKTRLDRYEPELNYVEKGAENDTTTPIAITQTIKRLLTGDVLSTSSKT +QLQFWMTNNMFSDSLARAVLPQGWLIADRSGGGVKGSRALTAMVWKSDRKPLFIGIFIAN +SSSTLPEINQVVADISQLIFAQy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0007C850BF +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAALREAGSAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Pandoraea TaxID=93217 RepID=UPI000685CB30 +---ADSPFSDIERRHGGRLGVFAIDTGSGRTL-SHRADERFLMCSTFKGLLAAQILSRVD +SGAERLDRLVHYTEKDLIFTSPVTKANVARGLSIDALCQATLVESDNTAAILLMRSAGGP +AALTRFVRGLGDPVTRSDRYEPESNRY--RGVLDTTTPKAITTTAQHLLLGDALSASSRA +QLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVESETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGTAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BF12AB +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALARFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Acetobacter indonesiensis TaxID=104101 RepID=UPI000A3BC004 +-----KALADYESRTGGHIGFFAQNVVTSASL-GWRASERFVMCSTFKASLAACVLSRID +QGHDTLEATLPFSAADIKDYAPVAKANLARGLTLRDLCAGAVEQSDNVCANLLLTHIGGP +SALTAFWRALGDTTTRLDAYEPELNRTPLGRLENTTTPTAMTSVLRAITLGPALSAPSRA +LLVQWMIACQTGTHRLRAGLPKHWVVGDKTGNNGKDAAGDIAVIWPKSDTPLLVCAYTRG +GKPTETDFATAFAAIGSLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Blastomonas sp. AAP25 TaxID=1523416 RepID=A0A0N0K248_9SPHN +--AIARELAAIEARSGGRLGVALVGPDGRQLA-GHRADERFAMCSTFKLPLAAMVLENAH +KGRLSMADPLPVNDSDMVVYSPYVEAQRAKTVTVEGAASAAVSLSDNTAANLLLDRLGGP +QSFTAWLRGKRDSVTRLDRREPELNENALGDPRDTTTPAAMADTTRSLVVGNAMPVGQQR +LLYRWMENTSTGLKRIRGGLPQGWSAGDKTGSCGN-AFNDVAVFTAETGMRYTLAVYLDR +PAVKGDAASAIIADATRAVL--- +>[subseq from] GES family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI000E093BB4 +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTLKFPLAALVFERID +PGTERGDRKLSYGPDMTVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonadales bacterium TaxID=2006849 RepID=A0A3N5KIZ2_9GAMM +----AARLQSLETG-QARLGVCFVDTATGEAS-GNRMNEHFAMCSTFKLALVAACLRQAD +QGRLDLAQVLTYSEADLLPWAPVTSKNLASGMSIGALAQAAQELSDGVAANLLVKRLGGP +AAVTAMFREMGDTVTRLDRYEPDLGLVLSADLRDTTTPLAMANLVRRITTADLLQSGSRE +RLLQWMQDTNTGPNRLRAGLPADWRSGNKTGTGRTNKCNDVAITFPPGRPPIVIAAYFDS +GEQTERRHEAVLAEVGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Leifsonia xyli TaxID=1575 RepID=A0A2W4ZSR4_9MICO +hrSVDRALADLEREYDATVGVVATDTVTGATV-AYNGDRRFGYASTIKVFAAAQFLRSVP +--TDARDEVVHWTAADVAAYSPVTEQHVADGLTYAQLAEAAVRMSDNTALNLVLTRIGGP +SGLDAALAELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALAAVLDGSTLNSADTA +LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAG-GIRNDVARVTPPDGDPIVLSVLTTR +NDPDAAYDDALVARSAAAVLDAf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RER1_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSG-PSGWLV---------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium chungbukense TaxID=56193 RepID=A0A0M3ARR2_9SPHN +--------KEIEAETGGRLGVALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAVLTGAE +GGKFGLEGQISFTKADLLDYAPVVRKNAKRGMSMEELAAAAVEVSDNSAANLLLPMIGGP +EGLTRYVRAHGDMVTRLDRTEPALNENAEGDERDTTSPAAMAGLMGRLIFRD-LKPESAE +KLRGWLNASTTGGNRIKAGLPKDWISGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDAKGAEAAIAETARAALD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. ms191 TaxID=1827978 RepID=A0A652JUJ5_9ACTN +--ELAAELRRLESARGVRIGAFAYDPASGRTL-SYRADESFPVLSTFKAFVAAAVLDKAR +RSPGLLERKVHWTARDEVSDSPTTRGRGVAGMTVAELCHAAVTRSDNTAGNLLLREIGGP +SGLTRHHRALGDPVTRLDRWEPELNDWHPGEPRDTTTPAAAGRALERVALGTALVPEDRA +RLNGWLRATVTGSERIRAGVPEDWEVGDKTGTSSYGGAHDIAVVRPRSGAPVVLAILTRR +TTAAAPSDSVSV----------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium czechense LL01 TaxID=1420583 RepID=A0A0J8AW20_9SPHN +--------AEIEKETGGRLGVALVD-RSGALLlGFNRDERFAMCSTFKAPLAAAVLIGAE +GGKFGLEGEIPFSGDDILDYAPVVKKNKKRGMSMGELAQAAVEVSDNSAANLLLPMLGGP +EGLTAFMRAHGDATTRLDRTEPTLNENAEGDPRDTTTPAAMAGLMGRLFFRDM-KPASVN +RLRSWFNASSTGDKRIKAGLPAGWTSGSKTGSCGT-AYNDVALVKAPNGDEYVLAIYLDR +PTVDAKKAEAAIAETARAALD-- +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=A0A2T3LV03_PHOAN +---VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ +INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP +VGVTTFLIDSGDSVTRLVRIEPLLNEATPGDKRDTTTPYAMNKTITNLVLGNALNESSKQ +QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG +TKASIPERDEEIAQIGQAILQQf +>[subseq from] Beta-lactamase class A n=1 Tax=Novosphingobium sp. B3058 49 TaxID=2183925 RepID=A0A2V5CM76_9SPHN +-----DPIAEYERTTGGRIGVHALNVTTGQTL-TWRADERFIMCSSYKASLAGYVLARVD +RGEEKLDALVPYTAQDTLGWGPIAKENLAKGMTVAAMCKAAVEISDGVCANMLMARSGGP +AGLTAFLRSIGDTTTRVDHFEPALDRVPSGGPDDSTTPAAMASTLQKVVLGDVLSAHSKE +LLTRWMIGNQT-TPRLRGGLPRNWRIGNKTGHSGRDMAGDIAVAWPHPEMPIVIAVYTRG +GSPAEAQFDKAFAGIGRLVAS-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A3M1WNX4_9BACT +--RLKSEIERLAELAGGRVGVGALHLETGRVV-YLHGDERFPMASTYKIPIAVQVLTRVD +REELTLDRLVTLRRRDLRPGSGLLARWLDESLSVHTLLELMLVISDNTATDVLLRLAGGP +SAVTKRLRELGIEGIRVDRPTLEIIAAFNADPRDTATPAAMVRLLQKVWRGRALSRERTE +LLFDIMRRCQTGARRIKGFLPPGTEVAHKTGTIG-GTTNDVGIITLPHGGHLALAVFVKE +STEEIAKREQAIAHIARALYDDf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=F4Y5N7_KLEOX +------------------------------------------MCSTSKVMAAAAVLKQSE +SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Mycetocola reblochoni TaxID=331618 RepID=A0A1R4JKZ6_9MICO +----EGRIDAIVDEAGVTLGVSAEDLSGAGTI-DAGSQEPVKAASVIKLPLLALLMDEAD +HGRLSLDESVTIPASNIVGGAGTLQGQFPLDITVRELMELMVQVSDNTATNVLIDRAGGF +DRINAYIEGLGYDTLWLGRKMI--HTATPPLGENWINAAEVTDLIARLYRHDILSASSSE +HIIGLMKGQLV-NTKFGAVIPRE-HLANKTGELGD-VSHDSGIILLDGHE-VALTVTSSY +AARSQTEVNRYVQRVASTVY--- +>[subseq from] Beta-lactamase n=2 Tax=Mycetocola reblochoni TaxID=331618 RepID=A0A1R4JKZ6_9MICO +-----------ARAAGVDVGVAVRDLSDDRAL-FLGKLDRYTTASTIKLALAATVMTQVQ +SGELDLDDVATITEDERYGGSGVLKDRAFPQVTVGEMLDLMVTVSDNTATNKLADVVGGV +DRISDVIAAAGISAGDLHFGRKMFGPVVPSWGDVWLTPVGMDQLLTSFYRQDYLTPESAR +TIIGLMLDQQV-KTKLGASIPAE-VLAHKTGENDT-VSHDVGLLLVPGQ-ELTLSVFTTA +GEDLQATANPYVQRIGAIVYEY- +>[subseq from] Beta-lactamase n=3 Tax=Aliivibrio salmonicida TaxID=40269 RepID=B6EJY3_ALISL +--SLNDTMIDLEKQTSGDIGVAVLDTKTNQIW-SYKGNQRFPMMSTFKTLACAKMLHDAD +KKIINKKTETAIAQKDLIPWSPITEKYVGKSISTEKACEATMLMSDNTAANIVLQQIGSP +SSLTAFLRLMGDSTTQLDRIEPTLNEAKKGDIRDTTTPIAMVHTINKLLLGNTLTTTDKV +TLKKWMMDNKVSDPLLRSILPIHWSIADRSGAGGYGSRGITAIIWNEHRLPLIISIYLTQ +TDLTLAERNDIIVHVGSALFTQf +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A249MXI0_9SPHN +--------RSIEEETGGRLGIALVDSKGALIL-GFNRDDRFALCSTFKAPLAAAVLIGAE +GGKFGLEGEIPFGKDDILDYAPVVKKNRKRGMSMAELAQAAVEVSDNSAANLLLPMVGGP +EGLTAFMRAHGDSVTRLDRNEPALNENAPDDPRDTTTPAAMAELMGRLLFRDM-KGESAD +RLRGWLNASTTGDNRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDAKAAEAAIAQAAQAALD-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium cupriresistens TaxID=1132417 RepID=A0A4Q4JPP7_9SPHN +--------AEIEKETGGRLGVALVD-RSGALLlGFNRDERFAMCSTFKAPLAAAVLIGAE +GGKFGLEGEIPFSGDDILDYAPVVKKNKKRGMSMGELAQAAVEVSDNSAANLLLPMLGGP +EGLTAFMRAHGDATTRLDRTEPTLNENAEGDPRDTTTPAAMAGLMGRLFFRDM-KPTSVD +KLRSWFNASSTGDKRIKAGLPAGWTSGSKTGTCGT-AYNDVALVKAPNGDEYVLAIYLDR +PTVDAKKAEAAIAETARAALD-- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium xenophagum TaxID=121428 RepID=UPI0005B88C35 +--------RSIEEETGGRLGIALVDSKGALIL-GFNRDDRFALCSTFKAPLAAAVLIGAE +GGKFGLEGEIPFGKDDILDYAPVVKKNRKRGMSMAELAQAAVEVSDNSAANLLLPMVGGP +QGLTAFMRAHGDSVTRLDRNEPALNENAPDDPRDTTTPAAMAELMGRLLFRDM-KGESAD +RLRGWLNASTTGDNRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDAKAAEAAIAQAAQAALD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. NEAU-Ht49 TaxID=2483351 RepID=A0A3M2LU22_9ACTN +--DVQKELRKLETSYQGRIGAYAIDTGTGKTV-GYRAHERMPSNSTFKAILCGAVLHKAR +ADPGLMSRTFHWTKEDVVDSSPVTGENIKNGLTAAQLCEATITTSDNTAANVLLKQVGGP +AGMTRYYRSLGDPAGRLDRYETELNHWNPGEKHDTIMPACMARDLEKLTVGTALVAEDRQ +QLTTWLKATDTGDERIRAGVPQGWIVGDKTGTADYAAADDIAIAWPPSGAPVIIAIFTHR +DAKDAAFDNRVLAKTTTILM--- +>[subseq from] Beta-lactamase n=1 Tax=Aliivibrio sp. 1S175 TaxID=1840087 RepID=A0A1B9PQ66_9GAMM +---VLETVETIELSSSGTIGVSVLDTETNTTW-SYKGDHRFPMMSTFKTLACAQMLYNSS +NNLLDKDALTRITKESIIPWSPITEKLIGETISTEKACEATMLMSDNTAANIVLAETGSP +KSLTLFLRLIGDDMTRLDRIEPALNEAQKGDVRDTTTPNAMTNTLNELLFGQTLNTKDKR +TLKAWMVDNKVSDPLLRSILPAKWSIADRSGAGGFGSRGITAIVWSNKRAPIIISIYLTQ +TNLDMASRNQIIVEVGNAIFKEf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingorhabdus sp. Alg239-R122 TaxID=2305989 RepID=UPI0013D99F2B +------ALRKLEQESGGRLGVACINAAGDTLF-ANRADERFAMCSTFKAPLAAALFEAHD +RGIADRFARIRVREDDFVPYAPFTENLVKEGTTLDEMAYQAVIISDNAAANIVLRAIGGP +EAFTDFLRRQGDDVTRLDRYEPELNENAIDDPRDTTSPLAMAGLLRRLLLKNEGSAAHAD +RLIKWMLDTKTGIARIRAGLPDAWRLGHKTGTAPQSCYNDVGIIFPPDQPPVLLAVYFDR +PDVAWKEAEAVIAETTRLAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. shizuoka-1 TaxID=2039281 RepID=UPI000C9CA21E +---IDQRIAALERRHNAFAGVYGQNLDSGQTV-TNRADDMFAMCSTFKAYLAARVLQKAQ +AGELRLTDTALVDPELLRANSPRTEPHVGTPMALSELCAAALQVSDNTAANVLLRVIGGP +PEITAFARSIGDERSRLDRWETELNSALPGDPRDTSTPSALGGGVRALLTGTVLDEPHRR +QLEDWMRANTT--SSMRAGLQPGWTTADKTGSGDFASTNDVGLLFGPAGERILLAIMTRT +QSDDAPGLRPLIGELTALVV--- +>[subseq from] class A beta-lactamase n=2 Tax=Mycolicibacterium canariasense TaxID=228230 RepID=UPI000A147CEB +---------EAELRHQARIGLYALDLKTQNTI-THRNHDRFAMCSSVKTYVAARVLQKAE +RGELALTDSVTVHGADIVPNSPVTETWVGRSIPVAELCAAALQKSDNAATNYLLKTVGGP +SAITEFARSIGDNETRLDRWETELNSATPGDARDTSTPQALGDGNRALLEGTALTLESRR +QLIEWMVANST--SSLRPGMPPEWILADKTGSGGYGSTNDVGLGFGPGGQQVVLSVMMRS +ATPNADGFRPVMTEIAAVAM--- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium czechense TaxID=1090573 RepID=UPI0009EBCC25 +--------AEIEKETGGRLGVALVD-RSGALLlGFNRDERFAMCSTFKAPLAAAVLIGAE +GGKFGLEGEIPFSGDDILDYAPVVKKNKKRGMSMGELAQAAVEVSDNSAANLLLPMLGGP +EGLTAFMRAHGDATTRLDRTEPTLNENAEGDPRDTTTPAAMAGLMGRLFFRDM-KPASVN +RLRSWFNASSTGDKRIKAGLPAGWTSGSKTGSCGT-AYNDVALVKAPNGDEYVLAIYLDR +PTVDAKKAEAAIAETARAALD-- +>[subseq from] GES n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SDD5_9BACT +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERGLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A521Q3P6_9SPHN +--------RSIEEETGGRLGIALVDSKGALIL-GFNRDDRFALCSTFKAPLAAAVLIGAE +GGKFGLEGEIPFGKDDILDYAPVVKKNRKRGMSMAELAQAAVEVSDNSAANLLLPMVGGP +EGLTAFMRAHGDSVTRLDRNEPALNENAPDDPRDTTTPAAMAELMGRLLFRDM-KGESAD +RLRGWLNASTTGDNRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDAKAAEAAIAQAAQAALD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID11385 TaxID=2706031 RepID=A0A6B2UPV2_9ACTN +-----AEFTALERRYAAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG +--RDGMGHVLRYGKKDVVANSPVTEKHVGTGMSREALCEAAIRYSDNTAANVLLADLGGP +RALGALVRATGDRVTRVERVEPLLSRWTPGETHDTTTPRQLTANLRAYVLGDVLAAPGRE +RLAGWLRANTTGNTTIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR +DERTAEADDRLLAEAARVVVS-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia oroxyli TaxID=366584 RepID=A0A1G7G479_9PSEU +------QLAALEDRFGGRLGVFAVDTGSGTTV-THRADERFLMCSTSKMLAAAAILALRV +DRPGLLDQQVSYPRSALVTYSPETERHD--AMTVRDLCHAAMTLSDNTAMNLLLETLGGP +ERLTGFLRREGDMISRQDRPETDLN--ILDGDKDTSTPAQVAANLRSFALDDGLDPGGRD +LLVGWLKANTTGATRIKAGLPADWVVGDKTGAGGQGEINDVAVVWPPGRAPLVMAVYTAP +ADPGSNGSPETVAEAARIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus pyridinivorans KG-16 TaxID=1441730 RepID=A0A0V9UL47_9NOCA +---VDERLREIEGRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA +EGSLRRDETLPIGPEDIVVNSPVTSEHQGRVLSIDRLCEAALTRSDNTAGNLMLQRIGGP +GAVTAFARSVGDEITRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGSGLPAPQQR +TLLGWMRATATSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS +TTPDAPLEGAPVAETTAVLVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudodonghicola xiamenensis TaxID=337702 RepID=UPI000426CA37 +---LDQTIDRIESELGARVGVAIHDSNTGSDW-THRGDERFLMNSTVKAPLCAAILSRDD +---IDLTETLPVRAEDILEYAPVTEKRVGTEMSIADLCLAALDQSDNTATNILFDRLGGP +EQLTEFLRSIGDDVTRSDRIEPGLNIFSAGDPRDTTTPKAMIDTLRAILVGDGLSEQDQE +QLAEWMRPGGVTGDLIRPAVPNGWDVVDKSGSGNN-TRNLIAMLTPPSEDPIFVSLSISD +TEADFGTRNAALKDLGAAVMK-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A2X4YMH0_KLEOX +--AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAILKQSE +SNKEVVNKRLDINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPESWVVGDK------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. EO9 TaxID=2304063 RepID=A0A418YW10_9SPHN +--------RTIEEETGGRLGIALVDSKGALIL-GFNRDERFALCSTFKAPLAAAVLIGAE +GGKFGLDGQIPFGKDDILDYAPVVKKNKKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP +QGLTAFMRAHGDSVTRLDRNEPTLNENAPGDPRDTTTPAAIAGLMGRLLFRDM-KGESAD +RLRAWLNASSTGDKRIKAGLPEGWTSGSKTGTCGT-AYNDVALVKAPSGEEYILAVYLDR +PSVNAKAAEAAIAQAAQAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009C02CA9 +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLERLVHYTESDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=A0A2T3PP28_PHOPO +--QIAPALTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TQRIHLNKPVLVKQSDILGYAPITKDRVGTTMTLAQLCDATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAMNSTLYSLLYGHALSETART +QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMADLNTAIAKIGQLIFTH- +>[subseq from] Beta-lactamase n=1 Tax=Fischerella sp. NIES-4106 TaxID=2005456 RepID=A0A1Z4TNH3_9CYAN +--ELYNRIEEISRTAQGRVGVAATVLETGESV-ALNGDQRFPMQSVYKFPIGMAVLAQVD +QGKLKLEQRIRVEKSDFVSHSPIRDEHPQGILSLTQLLKYMVSESDGTACDVLLKLVGGP +EVVTKYLRKLGVNGVIVVSTEKEIGQDKSVQYRNWATPEAMVVLLRALDEGRGLSKSSQA +LLLRLMTETSTGLRRIKGMLPDGTVVAHKTGTSGTAATNDVGLVTLPNSQHLAIAIFVSD +STADDAAREEVIAKVARTAWDKw +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A401J1R2_SPHXE +--------RSIEEETGGRLGIALVDSKGALIL-GFNRDDRFALCSTFKAPLAAAVLIGAE +GGKFGLEGEIPFGKDDILDYAPVVKKNRKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP +EGLTAFMRAHGDSVTRLDRNEPALNENAPDDPRDTTTPAAMAELMGRLLFRDM-KGESAD +RLRGWLNASTTGDNRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDAKAAEAAIAQAAQAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Carnobacterium divergens TaxID=2748 RepID=UPI0007F443A9 +------NFEKLEKKYEATLGVYGLDTETNKVV-AYNENQRFAFASTYKALAGGLVLNESS +--WDELNQTIMIKKEDLVTYSPITEKYVDIGMPLKELINAAIQYSDNTAGNFLFKQLGGP +KGFQTKLAELGDYTTDSSRFETELNEATPGDIRDTSTPKEIALDLKKLAIDHKLPTDKLE +FYKKQLIENTTGSKLIRAGVPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK +EQQESDYNDELIAETAKIVSDDf +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. ITM-2016-00318 TaxID=2099693 RepID=A0A2S8KIB0_9MYCO +----YDRIQALQRRYNTKIGVYAVDFASGRTV-SHLDGEPFAMCSTFKGYAAARVLQMVG +NGDLTLDQQVFVDPTAALPNSPRTAPNSGDRMTLGALCAAAVQVSDNCAGNLLLQTIGGP +SAITGFARSIGDDRTRLDRWEIELNSAIPGDPRDTSTPHALGDGYRTLLTGDALPPPQRQ +QLEDWMRANET--SSMLAGLPAGWTSADKTGNGDYGSTNDVGIAYGPAGQKLVLAIMTRS +QGPNAPNNRPLIGEVASVL---- +>[subseq from] Class A beta-lactamase n=1 Tax=Shewanella oneidensis TaxID=70863 RepID=A0A2W5DKM1_SHEOE +-----QTVNEFER-QGWNIGVSVIENSSNNVY-SINGDERFSTNSTVKALACAIVLSEVD +KNAVSLNDAMMINEQDVVSHSPVMKEFIGKKVTLADACKATMTYSDNTAANFAIKKSGGP +EGITSFLRSIGDDITRADRYEPDLNTNPEGDLRDTSTANTMAANFNKLLLGNILSTQSKE +QLKNWMMGNKVADNMLRLVLPTGWEIADRTGANSYGARGIISMVWSESQQPLIISIYIKK +EKTSIEEREKVISEIGRVIFTEy +>[subseq from] Class A beta-lactamase n=1 Tax=Carnobacterium divergens TaxID=2748 RepID=A0A659GIW1_CARDV +------NFEKLEKKYEATLGVYGLDTETNKVV-AYNENQRFAFASTYKALAGGLVLNESS +--WDELNQTIMIKKEDLVTYSPITEKYVDIGMPLKELINAAIQYSDNTAGNFLFKQLGGP +KGFQTKLAELGDYTTDSSRFETELNEATPGDTRDTSTPKEIALDLKKVAIDHKLPTDKLE +FYKKQLIENTTGSKLIRAGVPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK +EQQESDYNDALIAETAKIVSDDf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingobium phenoxybenzoativorans TaxID=1592790 RepID=UPI0009F4E93B +--------AAIEEASGGRLGIALVDSKGAMLL-GFNREERFAMCSTFKAPLAAAVLMGAE +QNRYGMEGTLPIKQTDLLDYAPVVKANLAKGMPIADLAKAAVQVSDNSAANLLLPLVGGP +QGLTAFFRKHGDEVTRLDRTEPALNENALGDERDTTSPAAMATVMARLLFQDM-PAPAAA +QLRGWLEGSTTGGKRIRAGLPAGWKAGDKTGSCGT-AFNDVAVLRSPRGNDYVLAIYLDR +PTVPDAKADATIAEATRAVMD-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Fischerella sp. PCC 9431 TaxID=1173023 RepID=UPI000478D5A6 +--ELYNRIEEISRTAQGRVGIAATVLETGESV-ALNGEQRFPMQSVYKFPIGMAVLAQVD +QGKLKLEQKIRVDKSDFVSYSPIRDDNPQGVLSLAQLLKYMVSESDGTACDVLLKLVGGP +EVVTKYLRQLGVNGVIVANTENEIGQDKSVQYRNWATPEAMVVLLRALHEGRGLSKSSRA +LLLRLMTQTPTGLRRIKGMLPNGTVVAHKTGSSRTAATNDVGLVTLPNRQHLAIAIFVSD +STADDAAREEVIAKVARAAWDKw +>[subseq from] Class A beta-lactamase n=1 Tax=Brevundimonas intermedia TaxID=74315 RepID=A0A4Y9RTT6_9CAUL +-------LNDLEERHGGRLGMAALDVGSQRRV-SWRGQERFAFCSTFKAFLAVATLERVQ +REEEQLDRAVAVTRADMIPHAPVTEKAIGRTLTIRELMQAAVEVSDNPAANILIREMGGI +AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPDQTIANIRELAFSDRLTPEHDQ +LITGWMIGSPTGANRIKAGAPQGWTVAHKTGTGSNGATNDIGMLTPLSGSPVLMAAYFTG +APATDDQRDAVIAEATRRALK-- +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=A0A2S7VXJ8_PHOAN +--TVNSAIEHAEKQLDARIGVSVLDGKGKQLF-GYNSDQRFPLMSTFKTLACAKLLHDNQ +INNGMMDKTYLINADTILDYAPIFKDKVGTEVSLKEACFATMTTSDNSAANLVLNHIDGP +VGVTTFLIDSGDNVTRLDRVEPLLNEATPGDKRDTTTPYAMNKTISNLVLGSALNESSKQ +QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGHGSRGITAVVWNEQKQPLVISIYLTG +TKASIPERDEEIAQIGQAVFKQf +>[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A251YCM8_9MICO +--AADAAFTALEERFGARLGVHAVDIGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMEGAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLMLRALGGP +AELDAALTALGDDTTVVARDEPTLNEATPGDDRDRTTPRAAAALMRAYALGDALDDDERT +LFTGWLRATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDATPIVIAVHSSK +DRQDAVADDALISGAAKAAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TverLS-915 TaxID=1839763 RepID=A0A1C4LU33_9ACTN +-----AEFTALERRYGAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG +--LAGMDHVLRYDKKDLVANSPVTEKHAGTGLSREALCDAAIRYSDNTAANVLLADLGGP +RALGALVRTTGDRVTRMERVEPLLSRWTPGETHDTTTPRQLTANLRAYTLGDVLAAPERE +RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR +DERTAEADDKLLAEATQVVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. Ant17 TaxID=1461752 RepID=A0A013WE99_9SPHN +--------KEIEQETGGRLGVALVDKQGALLL-GFNRDEPFAMCSTFKAPLAAAVLIGAE +GGKFGLEGEIPFGKDDLLDYAPVVKKNLKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP +QGLTAFIRAHGDSVTRLDRNEPDLNENAEGDPRDTTTPAAMAGLIGRLLFSDM-QGESAE +RLRGWLNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGDEYILAVYLDR +PTVDASKAEAAIAETARAALE-- +>[subseq from] Beta-lactamase n=1 Tax=Alishewanella aestuarii B11 TaxID=1197174 RepID=J2IG46_9ALTE +---AAQRLQALEVG-HARLGVCLLDTATGEVS-GNRMDEYFAMCSTFKLALAAAYLREAD +QGRLDLDEMLPYSEADLLPWAPVTREHLAKGMTIIALLQAAQQFSDGVAANLLVKRLGGP +AAVTAKFREMGDNITRLDRYEPDLGLVLSADLRDTTTPRAMAQLVQRITSGELLQPDSRQ +RLLQWMESTNTGSKRLRAGLPTTWRSGNKTGTGRTNKYNDIAITFPPGRSPIIIAAYFDS +GEQIEDRHQAVLAEVGRIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A2Z2Z6H0_9BACT +--TTKEEIQKIERQRNLTVGIALVDDGGTLLF-GHRETQRFAMCSTFKLPLAAATLKQIE +SGKWSAAERLSYSAGQLDAYAPAAKRYLPTGITVAEANQASVQLSDNTAANLLLDKLGGP +SQLTSMFRSLGDSVSRLDRREPDLNTNVSGDPRDTTTPGAMARIVAKLVYGNYLSTAGRE +QLQRLLIGNNTGDSRIRAGIASGWTTGDKTGSCPNGGRNDAAFLVSPDGRRFALTVYLNA +PSLDDKARNEVVATVARLAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. BK086 TaxID=2512165 RepID=A0A4R6I8E8_9MYCO +---LDQRIAALEKRHNAFVGLYGQNLDTKQVV-AHRDGDPFAMCSTFKAYLSARVLQKAQ +AGELALIDTVVVDPELLRPNSPRTEPNVGKPMALSDLCAAALQVSDNTAANLLLRVIGGP +PAITAFARSIGDQTTRLDRWETELNSALPGDPRDTSTPRALGGGILAVLTGDVLDEPHRT +QLEDWMRANTT--SSMRAGLPPGWTTADKTGSGDFASTNDVGIAFGPSGERLLLAIMTRT +QSANTPALRDLVGEVATL----- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000842198A +-----SPLAEIERRNGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLERLVHYTENDLIFTSPVTKANVAHGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. TNDT3 TaxID=2249354 RepID=UPI000E3EC7F3 +-----REFERLEEEFDARLGVYAVDTGSGEEV-EHRPDERFAYASTHKALTAALVLQQNT +--PEEMEEVVTFTEEDLVDYSPVTEQHVDTGMTLMEVADAAVRYSDNTAANLLFEELGGP +DAFEDELEAIGDDVTDPERIETELNDWTPGDTSDTSTPRAMAGNLREFTLGDALPEDRRE +VLNDLLVNNTTGDALIRAGVPGDWRVGDKTGAGSHGTRNDIAVIWP-------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=UPI000D17395F +--QIAPELTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAINSTLYSLLYGHALSETART +QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMADLNAAIAKIGQLIFTH- +>[subseq from] Beta-lactamase n=1 Tax=Plantibacter cousiniae TaxID=199709 RepID=A0A1T5I9I1_9MICO +--DLSGEFQALEAEFGARVGISAVDTGTGARL-SYRADERFGYASTIKALAAAVFLHEVR +--GSARDEVVTWSAEDVEAYSPVTSEHVETGLTLSQLAEAAVRQSDNTALNLVLARIGGP +AALDAALVTLGDEVTEVVNAEPLLNVIEPGSTDDTTTPAAFTDNLTRLVDGSYLESADRA +TLLAWMSGNATGDTLIRAGAPAGWQVADKSGGAG-GMRNDIAIIDRPGGDPIVLTILTNT +LDPDAEYDDALVAEAARVALAAf +>[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia oroxyli TaxID=366584 RepID=UPI000B80E9F3 +------QLAALEDRFGGRLGVFAVDTGSGTTV-THRADERFLMCSTSKMLAAAAILALRV +DRPGLLDQQVSYPRSALVTYSPETERHD--AMTVRDLCHAAMTLSDNTAMNLLLETLGGP +ERLTGFLRREGDMISRQDRPETDLN--ILDGDKDTSTPAQVAANLRSFALDDGLDPGGRD +LLVGWLKANTTGATRIKAGLPADWVVGDKTGAGGQGEINDVAVVWPPGRAPLVMAVYTAP +ADPGSNGSPETVAEAARIAA--- +>[subseq from] BETA-LACTAMASE n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0000112969 +-----KELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQSTYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium barthaii TaxID=1054037 RepID=A0A4R6FDC6_9SPHN +--------KEIESATGGRLGVALVDSKGALML-GFNRDERFAMCSTFKAPLAAAVLTGAE +GGKFGLEGQISFTKADLLDYAPVVKANLKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP +EGLTRFIRAHGDMVTRLDRNEPSLNQNVEGDERDTTAPAAMAGLMGRLIFRDL-APASAE +KLRGWLYASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDAKAAEAAIAETARAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=UPI0007F8A36C +--QIEPALTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAINSTLYSLLYGHALSETART +QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMADLNAAIAKIGQLIFTH- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacteraceae bacterium KEBCLARHB70R TaxID=2582866 RepID=A0A5R9JFJ0_9PROT +------AVALYERDSGGHVGVFAQNLRTGATL-AWRAGDRFVMCSTFKASLAACVLMQVD +RGLDSLASRIRYGAADIGDHAPVARANLASGLPVGEACEAAVEQSDNTCANLLLSRIGGP +PVLTSFWRRIGDDVSRLDDPEPILNFRAPGDAHDTTTPSAMADTLRRLVLGNVLSEGSRQ +ILIRWLLGCRTGGRRLRAGLPSSWRIGNKTGNNGGDAAGDIAVAWSARNAPIVMAVYTRG +GSPSAAQTDAVFAGIGRHI---- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 852002-51057_SCH5723018 TaxID=1834094 RepID=A0A1A2GAK9_9MYCO +-----DRLGELEGRYDAYVGLFATDLGSGRTL-AHRDGDPFAVCSTFKAYSAARVLQLAQ +RGELDLRQAVFIDPGALLPNSPVTAPQAGRTMPLAQLCAAALQRSDNAAANLLLRAIGGP +PAVTDFARSLGDEHTRLDRWETDLNTAIPGDPRDTSTPRALGGGIQSLLTGTVLGEPQRR +QLEDWMRGNVT--STMRASLPPGWTSADKTGTGDYGSTNDIGIAYGPGSQRVLLSVMTRS +ASKDADALGPLIAEVT------- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=UPI0009B998E4 +---VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ +INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP +VGVTTFLIDGGDSVTRLDRIEPLLNEATPGDKRDTTTPYAMNKTITNLVLDNALNESSKQ +QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG +TKASIPERDEEIAQIGQAILQQf +>[subseq from] Uncharacterized protein n=1 Tax=Rhizobium sp. AAP43 TaxID=1523420 RepID=A0A0N0JAY1_9RHIZ +--DIAQTAEQIEARLNLRIGLAVIDTGGGPGT-FRKADERFAMASTFKALACAAALDGGD +---AVLDRQSAVAQEDLQAYSPVTDKLVGARRTTRDFCAMMLRTSDNTAANKVLEAIGGP +TALTAFLRANGDEVTRLDRFEPDLNQATPGDPRDTTTPRAMAETMEKLVLGDALAVPAAR +QLEAWMAANSVAGGMLRASLPKDWAIADRGGAGGHGTRGIVAVIRPPARAPLVVAIYLDG +TQHPLKVRDAAMAELGAAIVAAy +>[subseq from] Beta-lactamase n=2 Tax=Pandoraea pnomenusa TaxID=93220 RepID=A0A378YLE1_9BURK +---ADSPFSDIERRHGGRLGVFAIDTGSGRTL-SHRADERFLMCSTFKGLLAAQILSRVD +SGAERLDRLVHYTEKDLIFTSPVTKANVARGLSIDALCQATLVESDNTAAILLMRSAGGP +AALTRFVRGLGDPVTRSDRYEPESNRY--RGVLDTTTPKAIITTAQHLLLGDALSASSRA +QLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVESETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGTAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BCABAC +-----SPLAEIERRNGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLERLVHYTENDLIFTSPVTKANVAHGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTHFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIATTAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia guartelaensis TaxID=2546446 RepID=A0A4R5LBA3_9BURK +--AAESPIAEVERRYGGRLGVFAVDTGSERTL-SHRADERFLMCSTFKGLLAAQTLARVD +SGEERLDRLVPYTEKDLIFTSPVTKANLAKGLPVETLCQAILEQSDNTAAVLLMRSAGGP +AGLTQFVRGLGDTVTRSDRYEPDSNHY--NGALDTTTPRAIATVARSLLLGDVLSPRSRA +QLERGMTACKPGLNRIRAALPEGWQAADRPGTSLTGETNDYALVRPPGRAPLLVAAYYDA +PGVSMQTRETVLREAGAAFVQ-- +>[subseq from] Beta-lactamase n=2 Tax=Listeria weihenstephanensis TaxID=1006155 RepID=W7CD33_9LIST +--QVKTALEKLEKKYGATLGIYGMD-GTGKQIiGFNEQERFAYTSTFKAIAGGILLKNLT +--DEQLNKRITFSKEDLVDYSPITEKHVASGMTMKEIINAAMDYSDNTAGNLMLHQLGGP +TGFEKELVKIGDKTMKPVRYETELNTAVPGDIRDTTTPEAMAKSLAYLVTEGNLPADRLA +YFKQTLINNTTGGKLIRAGVPDGYVVGDKTGAGSYGTRNDIAVIYPKDKKPLVWVIYSKK +TGKDDEYNDQLIADAAKVLSDYy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X166_9BACT +--EFAKNIEAIAKEARGVVGVGIMDLKSRETV-VLNPSHKFPMQSVFKFPLAMAVLDQVD +KGKFTLAQKIHVTKQDVSPWSPLSKKYPNGELTLAELLGYTVSMSDNNACDILFKLLGGP +KNVEDYIRTLGVKDIAIVATEEEMSKHWDVQFTNWCRPAAMLQLLDVIYKGKKLSQTSND +FLLKVMTETTTGPNRIRGLLPKDAKVAHKTGTSNTAASNDVGIMTLPNGKQVAVVVFVSN +AAADEKTRDAVIAKITKAAWDYy +>[subseq from] Beta-lactamase n=2 Tax=unclassified Pseudonocardia TaxID=2619320 RepID=A0A1Q8LKR3_9PSEU +-------MADVERTYARTIGVHVLDTGTGRSA-GHRDGDRFLMCSVTKALMAGFTLHRSL +SDPGLLARPVRYGRADLLEYAPVTTRNLATGMTVAQLCEAAVTVSDNTAHNLLLREVGSP +AELTAWLRTTGDTVTRSDRAETALNDR--DGERDTSTPAALASTLRALVLGDALPAPQRD +RLAGWLRANTTGDRQIRAAVPAGWVVGDKTGSGPLGERNDSGVLYPPDGAPLVLTVFTVP +ADADKPRGEAAVAAAARAAVA-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000C7000AB +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVGYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKTGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. 9120 TaxID=1500897 RepID=UPI0009DD07DD +----ESPIAGIERRYGGRLGLFAVDTGSGRTL-AYRADERFLMCSTFKGLLVAQVLARVD +AGKETLERLVHYTERDLIFTSPITKANVAQGMSVGALCQAAVEVSDNTAAILLMRSTGGP +AALTRFMRGLGDSVTRSDRYEPESNQY--SGLLDTTTPRAIATSAARILLGDVLSHQARR +QLEEWMVACKPGLNRLRAALPANWLAGDRPGTSVERETNDYAIVRPPGRAPLLVAAYYDA +PGVSMELRETVLREAGH------ +>[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI000A3702F9 +--AADAAFTALEERFGARLGVHAVDIGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMEGAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLMLRALGGP +AELDAALTALGDDTTVVARDEPTLNEATPGDDRDRTTPRAAAALMRAYALGDALDDDERT +LFTGWLRATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDATPIVIAVHSSK +DRQDAVADDALISGAAKAAAE-- +>[subseq from] Class A beta-lactamase n=2 Tax=Ideonella sp. KYPY4 TaxID=1862385 RepID=A0A437RLI8_9BURK +--ALQNELAALEARSGGRLGVAVLDTASGASA-GHRADSRFGLCSSFKLLLAAATIERVE +AGAWPSTRRIAYTAADLIPPSPVLRERLAEGLTALQMAQATQETSDNAAANLLLRELGGP +AGLTAWLRRQGDAVTRIDRWEPEMNVVAPGDERDTSTPAAIAATGARILTGPVLSPAGRE +QLIGWMVATQTGARRLRAGLPAGWKAGDKTGTGMPDRYNDVAIIWPGQRAPWLLAAYFES +RHRDRPEDEAVLAEVGRLV---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BDF360 +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIHAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAALREAGSAFV--- +>[subseq from] Beta-lactamase n=2 Tax=Xenorhabdus bovienii TaxID=40576 RepID=A0A077P7W3_XENBV +---LKDKIKNLEAQ-GWQVGVSILDYNGNKIE-SVNGDKRFPLDSTVKALACANVLAKVD +NKSLRLEDSVLINEKDIVTYSPITEGYVNKKITLKQACEATTAFSDNTAANIAISSVGGP +SELTKFMRSIGDNTTRSDRYEPDLTINPEHDLRDTTTPNAMSNSIRKLLTGNVLSEKSKE +QLKEWMIGNKVADNMLRAELPKGWFIADRSGASDYGIRGITSMVWSDKEPPLFISVYVRK +SNTSLEERSEKIAEIGMVIFSKy +>[subseq from] Beta-lactamase n=2 Tax=Bordetella genomosp. 8 TaxID=1416806 RepID=A0A1W6YMZ7_9BORD +----GSALADIERRNGGRLGVFAVDTATGRTL-AHRADERFLMCSTFKGLLAAQVLQRVD +GGAERLDRLVRYTEKDLIFTSPVTKANVGRGMSIEELCRAVLVESDNTAAILLMRSAGGP +AGLTRFVRGLGDTVTRSDRYEPDSNRA--DGAFDTTSPKAIATVAQGLLLGDVLSTNSRA +TLERGMADCKPGLNRIRAALPADWQAADRPGTNIDNETNDYALVRPPGRTPLLVAVYYDA +PGVKMDRREAVLREAGKAFVQ-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI00066D373A +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKTGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio logei TaxID=688 RepID=UPI0003C7BAEA +--SLNDTIIDLEKQTSGDIGVAVLDTKTNQIW-SYKGNQRFPMMSTFKTLACAKMLYDAD +KKIINKKTETAIAQKDLIPWSPITEKYIGKSISTEKACEATMLMSDNTAANIVLQQIGSP +RSLTAFLRLMGDSTTQLDRIEPTLNEAKKGDIRDTTTPIAMVNTINKLLLGNTLTTTDKV +TLKKWMMDNKVSDPLLRSILPIHWSIADRSGAGGYGSRGITAIIWNEHRLPLIISIYLTQ +TDLTLAERNDIIVHVGSALFSHf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Gloeocapsopsis sp. AAB1 = 1H9 TaxID=1433147 RepID=UPI000CF709C7 +-nELQDQIEQISHAAQGRVGVTATVLETGESV-ALNGDQRFPMQSVYKFPIGMAVLAQVD +QGKLKLDQRVRVEISDFVSHSPIRDENPQGVLNLAELLKYMVSESDGTACDVLLKLVGGP +EAVTQYLRDLGVDGIVVANTEKEIGQDKTVQYRNYATPDATAVLLRALYEGRGLSESSQA +LLLRLMTETPTGLKRIKGLLPDGTAVAHKTGTSRTAATNDVGIVSLPNKQHLAIAVFVSD +STADDAIREEVIAKVARAAWDEw +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium sp. Z007 TaxID=627495 RepID=UPI000B498257 +--------AEIEKEVGGRLGVALVD-RSGALLlGFNRDERFAMCSTFKAPLAAAVLIGAE +GGKFGLEGEIPFSGDDILDYAPVVKKNKKRGMSMGELAQAAVEVSDNSAANLLLPMLGGP +EGLTSFMRAHGDTVTRLDRNEPTLNENAEGDPRDTTTPAAMAGLMGRLFFRDM-KPESVD +KLRSWFNASSTGDKRIKAGLPQGWTSGSKTGTCGT-AYNDVALVKAPNGDEYILAIYLDR +PSVDAKKAEAAIAETARAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Sandarakinorhabdus sp. AAP62 TaxID=1248916 RepID=UPI0009DA0869 +--ALRRAISQIERSAGGPIGISLIDTQTGERF-GHRANDRFPLCSTFKLLLAARLLHGAD +KGEWTMNDRLPVTKADLLFNAPFTERRVGGSASLLELAEAMAVLSDNPAANIALARIGGP +VALTRWLRATGDRITRLDRNEPEMNNERPGDPRDTTTPTAMLATTRALVEGGILSSAARR +TLFGWMQASKTADSMIRAALPPGWQEANKTGAGSWHARNIVSVITPPGRKPIWVAAYLFA +AKSELGERNRQFVPLGRAIVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4P8JGB5_ECOLX +-------------------------------------------------MAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVL----------- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. B7740 TaxID=1564114 RepID=A0A0D5AGE5_9NOCA +--SAEQAYLELEARDTARLGVSVLDLETGSTQ-SYRGGERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTITAEDKVPESAVD-WDPGSVVTIADLAVAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPGDPRDTTTPDSLAAGYRTLLDGDVLAAASRK +QLLEWMGDTETSAARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT +TSDDSPAMNPLVADATRAAVQQ- +>[subseq from] Class A beta-lactamase n=1 Tax=Acinetobacter seifertii TaxID=1530123 RepID=A0A5E9PDR6_9GAMM +------------------------------------------------------------ +-------KRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium estronivorans TaxID=1577690 RepID=UPI0012399967 +--------KEIEAGTGGRLGVALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAVLTGAE +GGKFGLEGQVSFTKADILDYAPVVKKNAKRGMSMEELAAAAVEASDNSAANLLLPMVGGP +EGLTRYIRAHGDMVTRLDRTEPTLNENAQGDERDTTSPAAMAGLMARLIFTD-LKPASAD +KLRGWLNASTTGGNRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYVLAIYLDR +PTVDSKAAEAAIAETAGAALD-- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter tropicalis TaxID=104102 RepID=A0A511FIM8_9PROT +-------ISQYENETGGHVGFYAENTKTGATL-GWRTDERFVMCSTFKASLAACVLARVD +GGLDTLERPLSYTAADIGDYAPVAKANLAKGMTIRELCAGAVEQSDNTCANLLLTHIGGP +SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGPVLSAPSRT +ILTDWLIRCRTGEHRLHAGFPSAWKIGDKTGNNGKDAAGDIAVIWPHPETSIVVCAYTRG +GHPTEQQLSSVFAGIGKLVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A354EQH9_9CAUL +-------LADLEARHGGRLGVAALDVGSQRRV-SWRGQERFPFCSTFKAFLAVAILERVQ +RDEEQLDRAVPIVRTDMIPHAPVTEKAIGRTLTIRELIQAAVEVSDNPAANILIREMGGI +AVWRSWWPTFGDTTTLISRLEPDLNTALPDDPRDTCLPDQSIANIRELAFGDRLIPTHDQ +MIQGWMTASPTGPNRIKAGAPQGWTVAHKTGTGANGTANDIGVAFPLSGAPVILATYFTG +ATASDDQRDAVIAEATRRAFK-- +>[subseq from] class A beta-lactamase n=1 Tax=Carnobacterium divergens TaxID=2748 RepID=UPI00128D3967 +------NFEKLEKKYEATLGVYGLDTETNKVV-AYNENQRFAFASTYKALAGGLVLNESS +--WDELNQTIMIKKEDLVTYSPITEKYVDIGMPLKELISAAIQYSDNTAGNFLFTQLGGP +KGFQTKLAELGDYTTDSSRFETELNEATPGDIRDTSTPKEIALDLKKLAIDHKLPTDKLE +FYKKQLIENTTGSKLIRAGVPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK +EQQESDYNDELIAETAKIVSDDf +>[subseq from] Class A beta-lactamase n=1 Tax=Schumannella sp. 10F1D-1 TaxID=2590779 RepID=A0A506Y4Y4_9MICO +----ALDLAALEQRYDARLGVIATDTATGRTV-TWNADARFAHASTLKALAAGLVLKRE- +-GVAALDDPVAIPAAPLIDYSPVTEQHAGGTMTLGDVAAAAVELSDNTAGNLLFERLGGV +DALQRELRKLGDRTTRVDRPEPELNTATPGDSRDTSTPRALVSDLRSLAVGAALAKPERT +ALLGWLDGSQTGSTLIRAGLPTGWTAGDKSGAAGYGTRNDLAVVHPPNGAPIVIAVLSSR +DAADADYDDALIAAAASAAL--- +>[subseq from] Uncharacterized protein n=1 Tax=Frigoribacterium sp. Leaf44 TaxID=1736220 RepID=A0A0Q4M2N6_9MICO +--EVEAALADLETRYDARIGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLDATD +--DADLDRVVTWTQAEVDAYSPLTSTHVADGLPLRQLAEAAVRQSDNTALNLVLAELGGP +AGLDAALAAQGDDVTDVVHSEPELNRLTPGSTADTSTPAAFTATLARITDGDWLAADDRA +TLLEWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVVPPSGDPVVISVLTTR +NDPAARYDDALVAEAARIAL--- +>[subseq from] GES n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SDJ8_9BACT +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSPL +ASERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium sp. CCH11-B1 TaxID=1768781 RepID=UPI00082D9B60 +--------KEIEAETGGRLGVALVDANGALIL-GFNRDERFAMCSTFKAPLAAAVLIGAE +GGKFGLEGTIPFGKDDLLDYAPVVKKNLKRGMTMGELAQAAVEVSDNSAANLLLPMLGGP +DGLTAFMRAHGDTVSRLDRDEPALNENVEGDPRDTTSPAAMAGLMGRLIFRDM-AAESAA +KLRAWLNASSTGDKRIKAGLPEGWTSGSKTGTCGT-AYNDVALVKSPSGDEYILAIYLDR +PTVNAAKAEAAIAETAQAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00081DFBCC +-----AEFTALERRYGAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG +--LAGMDHVLRYDKKDLVANSPVTEKHAGTGLSREALCDAAIRYSDNTAANVLLADLGGP +RALGALVRTTGDRVTRMERVEPLLSRWTPGETHDTTTPRQLTANLRAYTLGDVLAAPERE +RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR +DERTAEADDKLLAEATQVVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. MI1205 TaxID=407020 RepID=A0A126R663_9SPHN +--------RTIEEETGGRLGIALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAVLMGAD +AGRFGLEGQVAFTDKDLLDYAPVVKANRKRGLSMEELAKAAVEVSDNSAANLLLPMIGGP +EGLTAFVRAHGDTVTRLDRVEPALNENAQGDPRDTTSPAAMAGLIGRLLFRDM-QAESAT +RLTSWLNASKTGDKRIKAGLPPGWTSGGKTGSCGT-AFNDVALVEAPSGERYILAIYLDR +PTVDAKAADAAIAEAARAALD-- +>[subseq from] Beta-lactamase n=3 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A1L5BLN4_SPHIB +--------KEIETESGGRLGVALVDGKGALIL-GFNRDERFAMCSTFKAPLAAAVLAGAE +GGKFGLEGQISFAKADLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP +EGLTRFIRAHDDMVTRLDRNEPSLNENAEGDERDTTSPAAMAGLMGRLIFRDL-APESAG +KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDAKAAEAAIAETARAALD-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia fungorum TaxID=134537 RepID=A0A3R7EAR7_9BURK +------SLADVERRNGGRLGVFAIDTGSGRTL-THRADERFLMCSTFKGLLAAQVLARVD +AGKEHPDRLVRYTEKDMIFTSPVTKAHLAEGMPVGALCQAIVEVSDNTAAVLLMRSAGGP +AGLTQFMRGLGDTVTRSDRYEPASNRY--SGVLDTTTPRSITKSVSQILLGNVLSPQSRA +QLEKWMIASTPGLNRLRAALPPDWIAGDRPGTSVEEQTNDYAIVRPPGRAPLLVAAYYDA +PALGMPAREAVLREAGAVFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=UPI000D17705F +--QIEPELTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAINSTLYSLLYGHALSETART +QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMTELNTTIAKIGQLIFTH- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CLI2509 TaxID=1984801 RepID=A0A249LRK8_9ACTN +-----AEFTALERRYGAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG +--LAGMDHVLRYDKKDLVANSPVTEKHAGTGLSREALCDAAIRYSDNTAANVLLADLGGP +RALGALVRTTGDRVTRMERVEPLLSRWTPGETHDTTTPRQLTANLRAYTLGDVLAAPERE +RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR +DERAAEADDQLLAEATQVVVR-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RJE3_9BACT +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKTGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Caulobacterales bacterium GWE1_67_11 TaxID=1797583 RepID=A0A1F8IBA7_9PROT +-------LNDLEARHGGRLGVAALDVASGRRV-LWRGQERFAFCSTFKAFLAAATLERVQ +RDEESLDRAVAVPRADIVPHAPVTEKAVGRTLTIRELMQATVEVSDNPAANILIREMGGI +AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPEQTLANIREMAFSERLTPENDA +LLHGWLTASPTGPNRIKAAAPEGWTVAHKTGTGANGTANDIAMLTPLSGSPVIVAAYFTG +ATATDDQRDAVIAEATRRALK-- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=UPI000D175BAA +--QIAPELTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGS +KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAMNSTLYSLLYGHALSETART +QLKQWMMDNKVSDPLLRAALPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMADLNAAIAKIGQLIFTH- +>[subseq from] Beta-lactamase n=2 Tax=Bordetella genomosp. 9 TaxID=1416803 RepID=A0A261R4J4_9BORD +----GSALADIERRNGGRLGVFAIDTATGRTL-AHRADERFLMCSTFKGLLAAQVLQRVD +SGAERLDRLVRYTEKDLIFTSPATKANVGRGMSIEELCRAVLVESDNTAAILLMRGAGGP +AGLTRFVRGLGDTVTRSDRYEPDSNRA--GGVFDTTSPKAIATVAQRLLLGDVLSTSSRA +MLERGMADCKPGLNRIRAALPADWQAADRPGTNIDNETNDYALVRPPGRAPLLVAVYYDA +PGVRMDRREAVLREAGTAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Microtetraspora malaysiensis TaxID=161358 RepID=UPI000A021638 +--DLDKTLQELEKSYNGRIGAVGIDLGTGKTV-GYRADERFPFNSMFKVFACAAVLHKAR +TAPGLMDKVVRWKPADMAENSPETTEYTDTGMTPAQLCRAGITKSDGFAGNTLLKQIGGP +GGLTEFFRATGDRTSRLDRPEPTLTQWKPGEERDTSTPAAAAQTFTKLTTGKTLHPRDRE +RLVGWLRANLTGDNRIRAGLPKDWTIGDKTGTGGYGTANDLAIVWAPGSAPIILSVFTNR +NVNNTPNDDTVIASTATALAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009C1A69F +-----SPLAEIERSNGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLERLVHYTESDLIFTSPVTKANVDQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] Class A beta-lactamase GES-42 n=12 Tax=Bacteria TaxID=2 RepID=A0A4Y5ULY1_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Roseomonas sp. TAS13 TaxID=1926319 RepID=A0A1Q2YN62_9PROT +--------IEYETSTGGHVGLHAENLRTGWKL-TSRSDERFVMCSTVKASIAACILSQVD +RGTIRLDDPIRFGANDVEGYAPVATENLGRGLSIREMCKAAVEESDNVCANFLLTRLGGP +AAMTAYWRSLGDRVSRLDDPEPILNRTPPGDVRNTTTPAAMAATLRRMVLGSALSPASRT +DLRTWMIGCKTGAHRLRAGIPSSWRIADKTGNNGKDGAGDIGVVWPKPDVPIVIVAYTRG +GTPTEQHFQKLFAGIGQEM---- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. DHOM06 TaxID=2291023 RepID=A0A3D8K287_9BURK +--AAESPLADIERRHGGRLGVFAVDTGSGRTL-SHRADERFLMCSTFKGILAAQILARTD +SGQERLDRLVHYTKNDLIFTSPVTKANLSRGMSVEALCQAILEESDNTAAILLMRSAGGP +AALTRFIRGLGDTVTRSDRYEPDSNRY--SGVLDTTSPRAIVTVARSLLLGDVLSPKSRT +RLERGMIACRPGLNRIRAVLPAGWQAGDRPGTSVESETNDYALVRPPGRAPLLVAVYCDA +PGVSMDDREAVLREAGKVFVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Carnobacterium divergens TaxID=2748 RepID=A0A5F0MIU8_CARDV +------NFEKLEKKYEATLGVYGLDTETNKVV-AYNENQRFAFASTYKALAGGLVLNESS +--WDELNQTIMIKKEDLVTYSPITEKYADIGMPLKELISAAIQYSDNTAGNFLFKQLGGP +KGFQTKLAELGDYTTDSSRFETELNEATPGDIRDTSTPKEIALDLKKLAIEHKLPTDKLE +FYKKQLIENTTGSKLIRAGVPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK +EQQESDYNDELIAETAKIVSDDf +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. GZWMJZ-114 TaxID=2494734 RepID=UPI001011C986 +-----AEFTALERRYGAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG +--LAGMDHVLRYDKKDLVANSPVTEKHAGTGLSREALCDAAIRYSDNTAANVLLADLGGP +RALGALVRTTGDRVTRMERVEPLLSRWTPGETHDTTTPRQLTANLRAYTLGDVLAAPERE +RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR +DERAAEADDKLLAEATQVVVR-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus sp. BUPNP1 TaxID=1432786 RepID=A0A225TMQ9_9NOCA +---VDERLKEIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA +EGTLRLDETLPIDPDDIVVNSPVTSEHQGRVLPLDRLCEAALTRSDNTAGNLMLQRIGGP +EAVTAFARSVGDGATRLDRWEPELNEAARGDQRDTTTAAGLSRGFGEVLLGSGLPAPQQR +TLLGWMRATTTSDTRIRGGLPSGWTSADKTGGGNHGTVNDAGVAWSPDGQPLLLVILSDS +TTGDP------------------ +>[subseq from] Beta-lactamase n=1 Tax=Hapalosiphonaceae cyanobacterium JJU2 TaxID=2109628 RepID=A0A328I8Y3_9CYAN +--ELYNRIEEISRTAQGRVGVAVTMLETGESV-TLNGDQRFPMQSVYKFPIGMAVLAQVD +QGKLKLDQRIRVEKSDFVSHSPIRDDNPQGVLSLAQLLKYMVSESDGTACDVLLKLVGGP +EVVMKYLRDLGINGINVVNTEKEIGQDKSVQYRNWATPEAMIVLLRALHEGRGLSKSSQG +LLLRLMTETPTGLRRIKGMLPDGTVVAHKTGTSRTAATNDVGLVTLPNRQHLAIAIFVSD +STAEDAAREEVIAKVARAAWDKw +>[subseq from] Putative beta-lactamase class A n=2 Tax=Novosphingobium TaxID=165696 RepID=U2Y7P4_9SPHN +--DLHERLGAIERAAGGTLGAYVLDTASGEGT-GWRQDERFAQCSSFKLSLAALALHLQE +AGEITLNERIAFTKADLLQHSPVTSQNLDTGMTIGELAQATMVTSDNAAANLLLHRFGGP +ERLTAFWRALGDDTSRLDRYEPELNDVPPGEIRDTTTPVAAAHTLARLLTDNALREPSRD +TLIRWMIAVETGGKRLRAGLPAGWRAGDKTGTGINATYVDIGWFELPSGQMVVVTSYFRP +GKTIDPGAEFALAEVGRVAAD-- +>[subseq from] Beta-lactamase PSE-4 n=1 Tax=Photobacterium sp. CECT 9192 TaxID=2006083 RepID=A0A1Y6MI31_9GAMM +--QISPELAKIEHQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TQRIDLNQAITIKQSDILSYAPVTTNRVGKSMTLAQLCNATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDKITRLDRIEPNVNNVSAAELRDTTTPIAINSTLYHLLYTDALSTSARA +QLKQWMMDNKVSDPLLRAVLPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMAELNTTIANIGQLIFQH- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A132DJG6_BURVI +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALARFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SA3_actF TaxID=682181 RepID=UPI0006822E19 +-----AEFTALERRYRAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG +--LAGMDHVLRYDKKDLVANSPVTEKHAGTGLSREALCDAAIRYSDNTAANVLLADLGGP +RALGALVRTTGDRVTRMERGEPLLSRWTPGETHDTTTPRRLTANLRAYTLGDVLAAPERE +RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR +DERTAEADDKLLAEATQVVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Tu6071 TaxID=355249 RepID=F3ZKP4_9ACTN +-----AEFTALERRYGAHLGVHAVDLGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG +--LAGMDHVLRYDKKDLVANSPVTEKHAGTGLSREALCDAAIRYSDNTAANVLLADLGGP +RALGALVRTTGDRVTRMERVEPLLSRWTPGETHDTTTPRQLTANLRAYTLGDVLAAPERE +RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR +DERAAEADDQLLAEATQVVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Biostraticola tofi TaxID=466109 RepID=A0A4R3YZF8_9ENTR +---LQALLKQQEMRLHARIGMSIVDAQGQPVF-GYRQHDRFPLTSTFKVLACAALLDSLH +QKAGSLEEKLTLQPGALLDYSPVTRDYLPPAISLGTLCKAAVSYSDNTAANRILTYLGGP +DAVTRFMRANGDQLTRLDRTEPTLNEARPGDVRDTTTPESMTVALHTLLATSLLTPPHRE +TLHGWMRDDKVADALLRAALPSGWDIADKTGAGGNGSRAIIAAVTPPEEPPFYLAIYITQ +TGASMKQADSAIASIGRHLF--- +>[subseq from] Class A beta-lactamase n=1 Tax=Altererythrobacter sp. HN-Y73 TaxID=2320269 RepID=A0A420EC05_9SPHN +-----DQLAALQSSTGGMLGAYILDTQSQKGF-GINEAQRFPHCSSFKLSLAALILQQAD +KGNLDLDERIHYTEADLMFVSPVTTRNLEKGMTLEELAKATQTTSDNAAANILLHRLGGP +EVLTGFWRSIGDSVSRLDKTEPALNKVEPGAVHDTTTPQAMAHTLSRLLTGDVLSDNSRA +KLWTWMQETRTGLDRIRAGLPQDWSAGDKTGTFFQDTYVDIAFVRPPDSAPLAITAYYRT +SDKMEPETLAILAKIGEIAH--- +>[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=Q3SAW3_PSEAI +--DFEHAISDLEAHNQAKIGVALVS-ENGNLIqGYRANERFAMCSTFKLPLAALVLSRID +AGEENPERKLHYDSAFLEEYAPAAKRYVATGMTVTEAIQSALQLSDNAAANLLLKEVGGP +PLLTKYFRSLGDKVSRLDRIEPTLNTNTPGDERDTTTPMSMAQTVSKLIFGDTLTYKSKG +QLRRLLIGNQTGDKTIRAGLPDSWVTGDKTGSCANGGRNDVAFFITTAGKKYVLSVYTNA +PELQGEERALLIASVAKLAR--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. DfronAA-171 TaxID=1839777 RepID=A0A1C4TA24_9ACTN +-----AEFTALERRYRAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG +--LAGMDHVLRYDKKDLVANSPVTEKHAGTGLSREALCDAAIRYSDNTAANVLLADLGGP +RALGALVRTTGDRVTRMERGEPLLSRWTPGETHDTTTPRRLTANLRAYTLGDVLAAPERE +RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR +DERTAEADDKLLAEATQVVVR-- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. ODNR1LW TaxID=2683260 RepID=UPI001412C290 +-------LSDLETAYGGRLGLAALDVGSGRRV-LWRAQERFPFCSTFKAFLAAATLERVQ +RDEEQLDRRVRITEADLIPHAPVTGPAVGRSLTIRELMQAAVEVSDNPAANILIREMGGI +AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPEQTLANIREMAFSDRLTPEHDA +LLHGWLTASPTGPNRIRAGVPEGWTVAHKTGTGANGATNDVGMLTPLSGSPVIIAAYFVG +ATATDDQRDTVIAEATRRALK-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI001068511B +--SHAQELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVGYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQHLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKTGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea sp. 6K102 TaxID=2530382 RepID=A0A4R5FT67_9ACTN +--NVKKQLRKLEASYQGRIGAFAIDTGTGRTI-SYRGGELFPSRSTFKAILCGAILAKAR +TEPGLLDRTLPWTAADVVSASPITGENIKNGMTVERLCHAAITISDNTAANLLLRQIGGP +AGPTRYCRSLGDRIGRLDRWEPELNDWKPGEKRDTVAPGSMARNLQKIAVGSTLVPKDRQ +RLNGWLRASTTGTERIRAGLPQDWIVGDKTGDAAYAPGSDIAVAWPPSGAPLIIAVYANR +NDPAATMDNSVIAKTATLLA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_002 TaxID=2175645 RepID=A0A2W1WFA7_9MICO +----EPALAALESEYGATIGVVATDTVTGASV-SHNRDRRFGYASSIKAFAAAEFLRSVH +--GADRDERVRWTAADVAAHSPVTEQHVADGLSYDELAEAAVRQSDNTALNLVLTRIGGP +SGLDAALADLGDDVTRVLHDEPELNTIEPGSTEDTTTPAAFAADLATVLDGDTLSGADTD +QLVAWMSGNATGDTLIRAGAPEGWTVADKSGGAG-GIRNDVALVTPPGGHPIAVAVLTTK +NDPGAVYDDTLVAKTAAVVLDAf +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=UPI0005EB561C +---VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQLFPLMSTFKTLACAKLLHDNQ +INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP +VGVTTFLIDGGDSVTRLDRIEPLLNEATPGDKRDTTTPYAMNKTITNLVLGNALNESSKQ +QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG +TKASIPERDEEIAQIGQAILQQf +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=UPI0009C0CB31 +--NIDSAIKHAEQQLGAKVGVSVLNANGDSLY-GYNSDQRFPLMSTFKTLACAKLLHDNQ +ITQGMMDKTYPVTANAILDYAPVFKDKIGTEVSLKDACFSTMTTSDNSAANFVLAHIGGA +EGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA +QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG +TEASIPERDKEIAKIGNAIFERy +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. J1-007 TaxID=2661913 RepID=UPI001324AE35 +--EVTKQLRALEASYRGRIGAYAIDTATGRTF-GHRSHERFPSNSTFKAILCGAVLNKAR +ADPGLMERTLHWTREEVVKNSPVAEENIKNGLTTARLCHAAITLSDNTAANVLLKQIGGP +AGMTRYYRSLGDPVGRLDRFEPELNEWQPGEKRDTIRPAFMAHSLAELTVGNALVPADRR +QLIDWMKASSTGGARIRAGLP-GWTVGDKTGTGGYANASDIAIAWPPSGAPVIITVYTNR +DGDHPEIDDGVIARTATLLA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=M1IEX6_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAPVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVG--------------------------------- +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. MWU12-2534b TaxID=2071715 RepID=A0A365VRQ1_9PSED +----------------------------------------------FKVMLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTIPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMD----------------- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingomonas sp. CDS-1 TaxID=2004404 RepID=UPI000B3C3196 +--------KEIETETGGRLGVALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAILTGAE +GGKFGLEGQISFTKADILDYAPVVKKNGKRGMSMEELAAAAVEVSDNSAANLLLPMIGGP +EGLTMFIRAHGDTVTRLDRTEPTLNENVEGDERDTTSPAAMAGLMGRLIFRD-LKTESAG +KLRGWLNASTTGANRIKAGLPKDWTAGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR +PTVDAKAAEAAIAETARAALD-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Fischerella muscicola TaxID=92938 RepID=UPI00030DAD1E +-nELYNQIEQISRTAQGRVGVAVTVLETGESV-TLNGDQRFPMQSVYKFPIGMAVLAQVN +QGKLKLEQRIRVEKSDFVSHSPIRDDNPQGVLSLAQLLKYMVSESDGTACDVLLKLVGGP +EVVMKYLRELGINGIIVANTEKEIGQDKSVQYRNWATPEAMIILLRALHEGRGLSKSSQT +LLLRLMTETPTGLRRIKGMLPDGTVVAHKTGTSRTAATNDVGLVTLPNGQHLAIAIFVSD +STADDTAREEVIAKVARAVWDKw +>[subseq from] BEL family class A extended-spectrum beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI0008FBAF28 +--DFEHAISDLEAHNQAKIGVALVS-ENGNLIqGYRANERFAMCSTFKLPLAALVLSRID +AGEENPERKLHYDSAFLEEYAPAAKRYVATGMTVTEAIQSALQLSDNAAANLLLKEVGGP +PLLTKYFRSLGDKVSRLDRIEPTLNTNTPGDERDTTTPMSMAQTVSKLIFGDTLTYKSKG +QLRRLLIGNQTGDKTIRAGLPDSWVTGDKTGSCANGGRNDVAFFITTAGKEYVLSVYTNA +PELQGEERALLIASVAKLAR--- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacteraceae bacterium OTSz_A_272 TaxID=1759059 RepID=A0A1B1AIV3_9CAUL +------RFATIERRIGGRVGVAALNTATGDWI-GRRIQERFAMCSTFKWLLAAHMLHFDS +HLPDYRDQRMRYTEADLLDYAPVTRANIVNGMSILELCRAAVVVSDNTAANLLLRIADGP +PGLTNFIRSTGDGITRLDRIEPELNVVPLGEERDTTTPDAMVRTLQRILLETILSGSHRE +RIIGWMVESPTGRERLRAGIPSSWRVGDKTGTWHNNATNDVAIAWPPNGAPIVIASYLHG +STVEPAQRNAAHAEIARIIVEQf +>[subseq from] class A beta-lactamase n=1 Tax=Roseibium denhamense TaxID=76305 RepID=UPI0012BCF27B +--ALENKLIALEKRENAKIGVALLDAETGHRF-SYRGSDRFALNSTFKAFACSALLARSE +TGQILMEDTRSIREQDLVPWSPVTENRTGTDITLFEACEATMVYSDNTAANVVLDALGGP +AALTAFMRSAGDTETRLDRIEPEMNVVPDGSLQDTTTPEAAAASLQTFVMGDVLNAKSKA +QLVEWLTANTTAKNMLRKHLPAGWSIGDRSGASRDRKRSVIAVIYPPNRLPLFAAVYLQL +QQAKISKRDAIIAEFAETLFD-- +>[subseq from] Beta-lactamase n=1 Tax=Hapalosiphon sp. MRB220 TaxID=1704290 RepID=A0A0M0SJS6_9CYAN +--ELYNRIEEISRTAQGRVGIAATVLETGESV-ALNGEQRFPMQSVYKFPIGMAVLAQVD +QGKLKLEQKIRVDKSDFVSYSPIRDDNPQGVLSLAQLLKYMVSESDGTACDVLLKLVGGP +EVVTKYLRELGVNGVIVANTENEIGQDKSVQYRNWATPEAMVVLLRALHEGRGLSKSSQA +LLLRLMTQTPTGLRRIKGMLPNGTVVAHKTGSSRTAATNDVGLVTLPNRQHLAIAIFVSD +STADDAAREEVIAKVARAAWDKw +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009C165FA +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALARFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1IZE2_9ZZZZ +-----------------------------------------------------------D +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Sulfitobacter geojensis TaxID=1342299 RepID=A0A196Q3U4_9RHOB +---LGVEIRALEKRHDARIGVMVRHPASGWYW-GYRENERFLMNSTFKSVLCAAILYQVD +RQVLDLNTKIKISGQDILHYAPVTKKNIGSALPISDLCFATLDQSDNTAANLLINLLGGP +KGVMTYLDRINDAVTRLDRIEPSLNDFVAGDPRDTTSPAAMTATWQKMLTGDALRPTSRA +QLAEWMRHGSVTQEFLRKSAPIGWQIIDKSGDGRKHTRSIVAMMTPLAAAPYFVAIYVSD +TPASWVERNAIVAEIGRAIID-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Hapalosiphon sp. MRB220 TaxID=1704290 RepID=UPI0006AA1E5C +--ELYNRIEEISRTAQGRVGIAATVLETGESV-ALNGEQRFPMQSVYKFPIGMAVLAQVD +QGKLKLEQKIRVDKSDFVSYSPIRDDNPQGVLSLAQLLKYMVSESDGTACDVLLKLVGGP +EVVTKYLRELGVNGVIVANTENEIGQDKSVQYRNWATPEAMVVLLRALHEGRGLSKSSQA +LLLRLMTQTPTGLRRIKGMLPNGTVVAHKTGSSRTAATNDVGLVTLPNRQHLAIAIFVSD +STADDAAREEVIAKVARAAWDKw +>[subseq from] Beta-lactamase Toho-1 n=1 Tax=Brevundimonas sp. SH203 TaxID=345167 RepID=A0A1V1UY48_9CAUL +-------LTDLEARHGGRLGVAAFDVGSHHRV-SWRGQERFAFCSTFKAFLAVAVVERVQ +RDEERLDRAVPVVRADMIPHAPVTEKAIGRTLTIRELMQAAVEVSDNPAANILIREMGGI +AVWREWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPDQTLANIRELAFGDRLTPPHDQ +MLQGWLMASPTGPGRIKAGAPQGWTVAHKTGTGANGTANDIGVAFPTSGSPVVLATYFTG +ATASDDQRDAVIAEATRRVFK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rhodococcus sp. TaxID=1831 RepID=A0A520EIF7_RHOSO +----EQPYSQLEARDAARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD +AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT +AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRE +QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT +TS--------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Xanthomonadaceae bacterium CU05-9 TaxID=2571175 RepID=UPI00117EEBC4 +--SFTAQVSDLTKSVDADVGIALVS-NDGKLLrEFNSGKRFAMCSTFKLPLAAMALQDAR +QGKYRLDHPLKFKKSDLDAYAPVATRYLPSGMTVLEAVHASVQLSDNTAANLLLRQAGGP +KVLTQAFRRWGDNVSRLDRNEPTLNTNLPGDPRDTSTPVAMAKLTARLVYGTLLDKQDRL +SLERLLIGNQTGDNTIRAGVPSSWIVGDKTGSCERGGRNDLAFLRSPAGKKYVLAVYVNA +PKIEAPKRDQLVAEITKLAL--- +>[subseq from] Beta-lactamase n=2 Tax=Celeribacter ethanolicus TaxID=1758178 RepID=A0A291GFV0_9RHOB +--------QDRERELTARIGVCVRNLATGQVY-LHRAEERFAMCSTFKASLAALCLRESD +EGALDLGEALAFGAEDLLPTSPVTKAYVQAGLEIRSLCQAVVEWSDNTAANLLLARVGGP +ASVTRFFRDMGDPVSRLDRVEMDLNSNSPGDARDTTTPLAMAQNVQRMTMEGVLSERSRS +LLVDWMRNEQNAKNRIRAAVPRSWEVANKPGTTPNGAANDIAMLWAPEGRAFAMAIYVDT +KKGNTPAAVSAIRGIAEVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Frigoribacterium sp. MEB024 TaxID=1589899 RepID=UPI0005BA12D8 +--EVEAALADLETRYDARIGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLDSTD +--DAELDRVVTWTQAEVDAYSPLTSTHVADGLPLRQLAEAAVRQSDNTALNLVLAELGGP +TGLDAALAAQGDDVTDVVHSEPELNRLTPGSTADTSTPAAFIATLARITDGDWLAADDRA +TLLEWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVVPPSGHPVVISVLTTR +NDPAAKYDDALVAEAARIAL--- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga sp. CF418 TaxID=1855287 RepID=A0A1M7NHL3_9BACT +----RKKIQEIAQTAHGHVGMAMMSLEDGDTI-TLNGKDRFPMQSVFKLPLAIAVLDQVD +KGKFALDQVIHIRKEDLLPWSPMREKFPEGTMKLSDILAYTVSQSDNSGCDLLFRLVGGT +TYVEEYIHSLGVDSIAIRATEEQAAKAWEVQYTNWSSPVAMLQLLKGVHTGKYLSKSSND +FLLKIMKETTTGPGRMRGLLPKEAVVAHKTGTSDTAATNDVGIVTLPNGKHYAIAVFVSD +TKANTATREAVIAQLTRLFWD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SolWspMP-sol7th TaxID=1839776 RepID=A0A1C4NIJ5_9ACTN +-----AEFTALERRYGAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG +--LAGMDHVLRYDKKDLVANSPVTEKHAGSGLSREALCDAAIRYSDNTAANVLLADLGGP +RALGALVRTTGDRVTRMERVEPLLSRWTPGETHDTTTPRQLTANLRAYTLGDVLAAPERE +RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR +DERAAEADDQLLAEATQVVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium quisquiliarum P25 TaxID=1329909 RepID=T0GI04_9SPHN +--------REIEKESGGRLGVALIDSKGALLL-GFNRDERFAMCSTFKAPLAAAVLMGAE +AGKFGLDGQVAFSKSDLQNHAPAVKANIKRGMSMAELAEAAVELSDNSAANLLLPFVGGP +EGLTAFMRSHGDAVSRLDRNEPGLNENAQGDERDTTSPAAMAGLMARLLFQDM-QPESAA +RLREWLNGSSTGDRRIKAGLPEGWTSGSKTGSCGT-AYNDVALIKAPSGEEYILAIYLDR +PTVEGKAAESAIADAARAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=Q5MJG5_PHOPO +--QIEPALTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAMNSTLYSLLYSHALSETART +QLKQWMMDNKVSDSLLRAALPVGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMADLNAAIAKIGQLIFTH- +>[subseq from] Beta-lactamase n=2 Tax=Auraticoccus monumenti TaxID=675864 RepID=A0A1G6Z5U4_9ACTN +-----DRLAELEAANDLTIGVWARNLRTGAEL-AHRADTLFPMCSVFKTLAVAAVLSLVS +PDPRVLRRPVHIPPANMVDYSPFVEECADRGPTVEQLCVATLQLSDNTAANELMALTGGP +ASITRMARRLGDDVTRLDRWEPELNSAEPDRVTDTTSPRAIGRTFTSLLTGRGLRPRERE +RLTGWMLGNQTSAARLRAALPAGWTLADKTGGSGYAVNNDVGVAWAPDGTPLALSVLVRS +DDPEAVRDDAVVAAAGRICVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Sulfitobacter geojensis TaxID=1342299 RepID=UPI0009ED4065 +---LGVEIRALEKRHDARIGVMVRHPASGWYW-GYRENERFLMNSTFKSVLCAAILYQVD +RQVLDLNTKIKISGQDILHYAPVTKKNIGSALPISDLCFATLDQSDNTAANLLINLLGGP +KGVMTYLDRINDAVTRLDRIEPSLNDFVAGDPRDTTSPAAMTATWQKMLTGDALRPTSRA +QLAEWMRHGSVTQEFLRKSAPIGWQIIDKSGDGRKHTRSIVAMMTPLAAAPYFVAIYVSD +TPASWVERNAIVAEIGRAIID-- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A2W6RP40_9CAUL +-------LSDLEARHGGRLGVAAFDIGSQRRV-SWRGQERFPFCSTFKAFLAAATLERVQ +RDEEQLDRAVAVVRADLIPHAPVTERAVGRTLTIRQLMQAAVEVSDNPAANILIREMGGI +AVWRSWWPRFGDTTTLISRLEPDLNTALPNDPRDTCLPDQTVANIRELAFGDRLTPEHDQ +MIQGWMTASPTGPNRIRAGAPAGWTIAHKTGTGANGTGNDIGMAIPLSGSPIVLATYFTG +AAATEDQRDAVISEATRRVFR-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. (strain SPB78) TaxID=591157 RepID=D9UN36_STRS3 +-----AEFTALERRYGAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG +--LAGMDHVLRYDKKDLVANSPVTEKHAGTGLSREALCDAAIRYSDNTAANVLLADLGGP +RALGALVRTTGDRVTRMERVEPLLSRWTPGETHDTTTPRRLTANLRAYTLGDVLAAPERE +RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR +DERAAEADDKLLAEATQVVVR-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas paucimobilis TaxID=13689 RepID=A0A031JGZ5_SPHPI +--------REIEKESGGRLGVALIDSKGALLL-GFNRDERFAMCSTFKAPLAAAVLMGAE +AGKFGLDGQVAFSKSDLQNHAPAVKANIKRGMSMAELAEAAVELSDNSAANLLLPFVGGP +EGLTAFMRSHGDAVSRLDRNEPGLNENAQGDERDTTSPAAMAGLMARLLFQDM-QPASAA +RLREWLNGSSTGDRRIKAGLPEGWTSGSKTGSCGT-AYNDVALIKAPSGEEYILAIYLDR +PTVEGKAAESAIADAARAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Aeromicrobium massiliense TaxID=1464554 RepID=UPI0006760A52 +-------LRDLERRHDARLGLLAVDTGTGTVV-AHRPDERFAHASAGKLLLAGAVLERRG +--TVGLDERVRVP-DETVPHSPVTESRTGRTLTWAEVLDAALRLSDNTAANLLAQDAGGP +DAVTEVLRAWGDDVTRVDRLEPDVNTAVPGDERDTSTPRVLAGHVRALVLGDRLAEPARE +RLVGWMRASTTGTALVRAGVPSGWAVADRSGGAAYGSRHDLAVVWPPHGAPLVLAVMTSR +RGQDDEGRDALVAQAAGVAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. EV170527-09 TaxID=2603411 RepID=A0A5B0IEJ9_9PSEU +-------MADVERTYARTIGVHVLDTGTGRSA-GHRDGDRFLMCSVTKALMAGFTLHRSL +SDPGLLDRPVRYGRADLLEYAPVTTRNLATGMTVAQLCEAAVTVSDNTAHNLLLREVGSP +AELTAWLRTTGDTVTRSDRAETALNDR--DGERDTSTPAALASTLRTLVLGDALPAPQRD +RLAGWLRANTTGDRQIRAAVPADWGVGDKTGSGPLGERNDSGVLYPPDGAPLVLTVFTLP +ADADEQRGEDAVAAAARAAVA-- +>[subseq from] class A beta-lactamase n=3 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI00141E73A6 +--TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS +LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTSFARESGATSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGDTLQEPQRT +QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSF-- +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A7KEG2_KLEPN +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVA---------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. D43FB TaxID=2017595 RepID=A0A2A3MRG8_9SPHN +--------KEIEQETGGRLGVALVDKQGALLL-GFNRDEPFAMCSTFKGPLAAAVLIGAK +GGKFGLEGEISFSKDDILDYAPVVKANRKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP +QGLTAFMRAHGDSVTRLDRNEPELNENAEGDPRDTTTPAAMAGLMGRLLFRDM-QGESAE +RLRGWLNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGDEYILAVYLDR +PTVDAKKAEAAIAETARAALE-- +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL23I1N1 TaxID=1938802 RepID=A0A420A2M6_9BURK +------PLADIEHRNGGRLGVFAIDTGSGRTL-SHRADERFLMCSTFKGMLAAQILARVD +SGSEQLDRLVHYTEKDLIFTSPVTKANVARGMSIDALCRAVLVESDNTAAILLMRSAGGS +AALTRFARGLGDTVTRSDRDEPDSNRY--DGELDTTTPRAIATTAQRLLLGDVLSASSRV +QLERGMTDCRPGLNRIRAVLPAGWQAADRPGTSVERETNDYALVRPPGQAPLLVAVYYDA +PGVSMDAREAVLREAGAALL--- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium quisquiliarum TaxID=538379 RepID=UPI000688A29C +--------REIEKESGGRLGVALIDSKGALLL-GFNRDERFAMCSTFKAPLAAAVLMGAE +AGKFGLDGQVAFSKSDLQNHAPAVKANIKRGMSMAELAEAAVELSDNSAANLLLPFVGGP +EGLTAFMRSHGDAVSRLDRNEPGLNENAQGDERDTTSPAAMAGLMARLLFQDM-QPESAA +RLREWLNGSSTGDRRIKAGLPEGWTSGSKTGSCGT-AYNDVALIKAPSGEEYILAIYLDR +PTVEGKAAESAIADAARAAL--- +>[subseq from] Uncharacterized protein n=3 Tax=Frigoribacterium TaxID=96492 RepID=A0A0Q6B597_9MICO +--EVEAALADLESRYDARIGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLEATD +--DADLDRVVTWTQAEVDAYSPLTSTHVADGLPLRQLAEAAVRQSDNTALNLVLAELGGP +AGLDAALAAQGDDVTDVVHSEPELNRLTPGSTADTSTPAAFTATLARITDGDWLAADDRA +TLLEWMSRNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVVPPSGDPVVISVLTTR +NDPAARYDDALVASVAEVAL--- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium sp. DC-2 TaxID=1303256 RepID=UPI0009DEF370 +--------REIEKESGGRLGVALIDSKGALLL-GFNRDERFAMCSTFKAPLAAAVLMGAE +AGKFGLDGQVAFSKSDLQNHAPAVKANIKRGMSMAELAEAAVELSDNSAANLLLPFVGGP +EGLTAFMRSHGDAVSRLDRNEPGLNENAQGDERDTTSPAAMAGLMARLLFQDM-QPESAA +RLREWLNGSSTGDRRIKAGLPEGWTSGSKTGSCGT-AYNDVALIKAPSGEEYILAIYLDR +PTVEGKAAESAIADAARAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio toranzoniae TaxID=1194427 RepID=UPI001378F31E +------------EKLGWSIGVTVLETDNGEKE-SIHGDKRFHFNSTIKALACANILEKSD +KNIISLDDSIKLKKGDIVTYSPVTKDYVGRNLTLKQACDATLTYSDNTAANYTISAGGGP +NGLTKFMRSIGDDVLRSDRYEPELTKNIEYDIRDTTTTNAMTSSLNKILLGNVLSDSSKK +QLRAWMEGNKVADNLLRVSLPSGWSIADRSGASDYGVRGIIALAWSESNSPVIIAMYVRK +EGTSMAERDQVIADLGHVIFDKy +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter colistiniresistens TaxID=280145 RepID=N9PKQ7_9GAMM +--ALEEQVKSL-SEKGWQVGVSILDME-NKRI-SINGDKRFPLDSTVKALACAHVLAQVD +AKKLTLDHSKTIRQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP +AGLTSFMRSIGDEVTRSDRYEPDLVINPEGDIRDTTSPNAMNDSMKKLLMGDVLSKSSKE +QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGITSMVWAENHAPVFISIYVRK +SETSLDERSAVIKLLSEHIVKE- +>[subseq from] Class A beta-lactamase n=2 Tax=Legionellales TaxID=118969 RepID=A0A3B9RW06_9GAMM +--SIQEQLAELEVSSKGRIGIYVINTANNTHI-GYRADEHFPMGCTAKVIGVAAILNQSM +NQHDLLSQKISYSTNDLTNWSPITKQHLATGLTIKQLCAAAISFSDNTAMNLLVKQMGGL +NEMTHFAHTLGNTSFRQDNNWPEAYSGGKDNLDDSSTPKDMADSLQKLAFTDALAKPQRE +MLVSWLKANTTGDFRIRAGLPKVWAVADKTGTGGYGTTNDLGIIWPPKCAPIVMVIYYTS +DDKTAKKRDDIVASATQLLIS-- +>[subseq from] Beta-lactamase n=1 Tax=Plantibacter sp. PA-3-X8 TaxID=2480625 RepID=A0A3G8VNF0_9MICO +--DLSGEFQALEAEFGARVGISAVDTGTGARL-SYRADERFGYASTIKALAAAVFLHEVR +--GSARDEVITWSAEDVEAYSPVTSEHVETGLTLSQLAEAAVRQSDNTALNLVLARIGGP +AALDAALVTLGDEVTEVVNAEPLLNVIEPGSTDDTTTPAAFTDNLTRLVDGSYLESADRA +TLLAWMSGNATGDTLIRAGAPAGWQVADKSGGAG-GIRNDIAIIDRPGGDPIVLTILTNT +LDPDAEYDDALVAEAASVALAAf +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=D2KNX6_STAAU +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Actinokineospora terrae TaxID=155974 RepID=A0A1H9X8W8_9PSEU +-----------------------MDTKRDRTV-SYQADERFAYASTSKAFAAALVLDATT +--PQQLEEPVPIRAADLVANSPVVERAVGGTMTWRELCDAAVRYSDNAAGNLLLRSLGGP +AGLQA---GLGDQVTSADRYEPDLSSAIPGDPRDTSTPRTMATNLRKFTVDTALPEEDRA +MLDDWLRNNTTGTDVIRAGVPRDWVVGDKTGSADYGGRNDIAVLWPPGRDPIVIAVLTSR +DKEGAERLDALVADTARIVA--- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingomonas paucimobilis TaxID=13689 RepID=UPI00068C5E4E +--------REIEKESGGRLGVALIDSKGALLL-GFNRDERFAMCSTFKAPLAAAVLMGAE +AGKFGLDGQVAFSKSDLQNHAPAVKANIKRGMSMAELAEAAVELSDNSAANLLLPFVGGP +EGLTAFMRSHGDAVSRLDRNEPGLNENAQGDERDTTSPAAMAGLMARLLFQDM-QPASAA +RLREWLNGSSTGDRRIKAGLPEGWTSGSKTGSCGT-AYNDVALIKAPSGEEYILAIYLDR +PTVEGKAAESAIADAARAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium helvum TaxID=1534349 RepID=UPI00138B8AED +---VEQRIADLEKRHNAFVGLYGQNLASTVSL-AHRDGDPFAMCSTFKAYLSARVLQKAQ +VGELRLTDTVAVDPDLLRPNSPRTEPNVGKPMALSDLCAAALQVSDNTAANLLLRVIGGP +PAITAFARSIGDERTRLDRWETELNSALPGDPRDTSTPRALGGGTLTVLTGSVLDEPHRK +QLEDWMRANTT--SSMRAGLPTGWTTADKTGSGGFASTNDVGIAFGPNGERVLLAIMTRT +RSANAPALRDLIAEVTTVA---- +>[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium sp. B-7 TaxID=1298855 RepID=UPI0003B6E910 +---TANPIAEYEHTTGGRIGVHALNVTTGQTL-SWRADERFIMCSSYKASLVAFVLARID +RGQEKLDALVPYTAQDTLGWGPIAKENLAKGMTVAAMCKAAVEISDGVCANMLLARSGGP +AALTAFLRSIGDTTTRVDHFEPALDRVPSGGPDDSTTPAAMASTLQKVVLGDVLAARSKG +LLTRWLIGNQT-NPRLRGGLPQSWRIGNKTGHSGRDMAGDIAVAWPHPGMPIVIAVYTRG +GRPTEAQFDKAFAGIGRLVAS-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009C10E7E +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALARFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAALREAGSAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BD0475 +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALARFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAALREAGSAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium algorifonticola TaxID=2008318 RepID=A0A437J745_9SPHN +--------RKIEAATGGRLGIALVDREGNLLI-GFNREERFAMCSTFKAPLAAAVLMGAE +KGRYGMDGTLPVTQADLLDYAPVVKANLKKGMAIADLAKAAVEVSDNSAANLLLPLVGGP +DGLTAFLRAHGDALTRLDRTEPALNENAPDDPRDTTSPVAMATVMARLLFQDM-PAAAAA +RLRGWMEASSTGAARIRAGTPADWTVGSKTGTCGT-AYNDVAILRSPSGRDYVLAIYLDR +PTVDAKAAEAGIAEAARAAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Legionella yabuuchiae TaxID=376727 RepID=UPI0010556AAB +--SIQKKFAELEASSKGRIGIYAINTANHTHL-DYRANERFPTGCTSKVIGVATILSQSM +NDPTLLSQRISYSKNDLTHWSPITKKYLSSGMTVEQLCAASISYSDNTAMNLLVKKMGGL +EQMTLYARSLGNNSFRQDNWPEEAYSGGKGNLKDSSTPEDMAKSLQKLVFTDVLAKPQRK +MLMAWLNANTTGDFRIKAGLPKGWRVADKTGTGGYGTTNDLGVIWPPGCDPIIMAIYYTS +DDKLAEKRDDVIASSTRLLIN-- +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus kloosii TaxID=29384 RepID=UPI000D1E1187 +--SHADELKNLEKKYNANVGVYALDTKSGKEI-KFNADKRFAYASTSKAVNSAMLLEQVP +--YDKLDKKVHINKSDIVDYSPVLEKYVGKDITVKELIKASMMYSDNTANNKIIDELGGY +KQIRKNLKELGDNTTQPSRYEPDLNNYSPKDKRDTSTPKAYGKTMKKLIEKDDLSKKNKD +FLLDLMFNNKNGDTLIKDGVSKKYKVADKSGQATYASRNDIAYVYPKGQKPIVLVIFTNK +DDKNAKPNDKLISETAKKVMKEf +>[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea sp. WAC 01424 TaxID=2203200 RepID=A0A429AVH0_9ACTN +--EVKEQLRALEVSYRGRIGAYAIDTGTGKTL-SYRGGELFPSRSTFKAILCGAILTKAR +TDPGLLQRTLHWTAQEVVANSPISEENVKNGMTVDRLCHAAITVSDNTAGNVLLKQIGGP +AGLTRYYRSLGDPVGRLDRWEPELNDWKPGEKRDTVKPAFMARSLSKLTVGDTLEPKDRQ +RLNEWLRASTTGPERIRKGLPSTWTVGDKTGGAAYAPGSDIAVAWPPTGAPLIIAVYTNR +DDPAATMDDSVIAKTATFL---- +>[subseq from] Class A beta-lactamase n=1 Tax=Photobacterium aquimaris TaxID=512643 RepID=A0A2T3IHT0_9GAMM +--QISPELAKIEHQLGGTVAVAVYNANTNTSW-NYHGEQRVPMMSTFKTLACADLLHQAD +TQRIDLNQAITIKQSDILSYAPVTTDRVGTSMTLAQLCNATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDKITRLDRIEPNVNNVSTAELRDTTTPIAINSTLYHLLYTDALSTSARK +QLKQWMMDNKVSDPLLRAVLPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMAELNTTIANIGQLIFQH- +>[subseq from] class A beta-lactamase n=1 Tax=Legionella spiritensis TaxID=452 RepID=UPI000F6D285B +-kTLPQQLQQIEQRNGGRIGISVLNTGNQHQI-NYRANQRFPMGCTSKVIGVSAVLNKSM +TDPMLLGKKITYQTIDLASWSPVTGKHVKDGMTVEALCSAAIRYSDNTAMNLLVKELGGL +EAINAYAKQLGDHQFRQDNIWPDEAFSGGDDPYDSSSPAAMTNNLRQLLLERGLGEKQHK +LLQSWMLSNTTGDKRIRAGVPASWKVADKTGTGAYGTTNDIGVIWPGACSPIVMSVYFTQ +NRKHATPNDRVIVDVTKSVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCBA15_008 TaxID=1898736 RepID=A0A1S2HEQ8_9MICO +---VDRALAALETEYDATVGVVATDTVTGESV-THDGDHRFGYASTVKAFAAAQFLRSVR +--GSDRDEVVHWTAADVAAHSPVTEQHVGDGLSYAALAEAAVRQSDNTALNLVLTRIGGP +SGLDAALHDLGDDVTQVVHDEPDLNTIEPGSTEDTTTPAAFAADVAAVLDGTTLDTADRA +QLLDWMGGNATGDTLIRAGAPEGWTVADKSGGAG-GIRNDVALVTRPGGDPIVIAVLTTR +NDPDAAYDDALVAKTASVVLGAf +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter indonesiensis TaxID=104101 RepID=A0A252AYJ0_9PROT +-----KALADYESRTGGHIGFFAQNVVTGASL-GWRASERFVMCSTFKASLAACVLSRID +QGHDTLETTLPFSAADIKDYAPVAKANLARGLTLRDLCAGAVEQSDNVCANLLLTHIGGP +SALTAFWHALGDTTTRLDAYEPELNRTPLGRLENTTTPTAMTSVLRAITLGPALSALSRA +LLVQWMIACQTGTHRLRAGLPKHWVVGDKTGNNGKDAAGDIAVIWAKSDTPLLVSAYTRG +GKPTETDFATAFAAIGSLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter sp. CIP 64.2 TaxID=1217694 RepID=N9N3L4_9GAMM +---LEEQVKSL-SEKGWQVGVSILDME-NKRI-SINGDKRFPLDSTVKALACAHVLAQVD +AKKLTLDHSKTIRQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP +AGLTSFMRSIGDEVTRSDRYEPDLVINPEGDIRDTTSPNAMNDSMKKLLMGDVLSKSSKE +QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGITSMVWSENHAPVFISIYVRK +SETSLDERSAVIKLLSEHIVKE- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A212MHV5_KLEPN +--------------AVGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIA--------------------------------- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Frigoribacterium sp. ACAM 257 TaxID=2508998 RepID=A0A5C6PY07_9MICO +--DVADDLAALEAEFDARVGVSVVDTGTGATV-SHRADERFGHASSLKALAAAQFLHDVP +--VDQRDEVVTWTAGDVEAYSPLTSEHVADGLPLAQLAEAAVRQSDNTALNLVLDRIGGP +AGLDRGLDDIGDSTTEVVNREPALNTIEPGSTDDTTTPAAFAADLVALLDGRWLDDADRS +LLLDWMSGNATGDTLIRAGAPAGWVVADKSGGAG-GIRNDVAVVTPPGRAPVVVTVFTAR +NDPDARYDDALVARAASIVL--- +>[subseq from] Beta-lactamase n=1 Tax=Listeria rocourtiae TaxID=647910 RepID=A0A4R6ZHN1_9LIST +--KFKSEIEKLEKKYGATLGIYGMNTENKQTI-SYNAQERFAYASTFKAIAGGILLKNLT +--DDELNKRFYFSKEDLVDYSPVTEKHIDSGMTMKELIQAAMDYSDNTAANIMLRELGGP +EGFKKELLKIGDKTMLPVRYEPELNEAVPGDTRDTTTPEAMANSLSFLLTKGNMAEDRLH +LFKQMLFDNTTGDNLIRAGVPKGYIVGDKTGAGWYGTRNDIAAIYKDDAKPLIWVIYSKK +TGRDDEYNDQLIADAAKVLSDYf +>[subseq from] class A beta-lactamase n=1 Tax=Listeria riparia TaxID=1494964 RepID=UPI00068D17CA +--QAKEALKQLEKKYGSTLGVYAVNPKTSHTL-QYNAQERFAYVSTYKAIASGVLLKNLT +--EQQLEKRVFFKKEDLVDYSPVTEKHVESGMTIKEIIHAAVAYSDNTAGNLLFNALNGP +KGFQDELRKIKDETTNADRYETELNVAVPGDPRDTSTPEAFSKNLAFLTRQGNLQPKQLD +YFKQTLIENTTGGKLIRAGIPKDYIVGDKTGAGSYGTRNDIAVIYSDDREPLVWVIFSKK +DKEDATYDDQLIADASKVLSQYf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0011F326D1 +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKTGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. AP49 TaxID=1144307 RepID=J2WQ64_9SPHN +--------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAE +GGKFGLDGEIPFTKDDILDYAPVVKKNRKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP +EGLTAFMRAHGDKITRLDRNEPALNENIEGDGRDTTSPAAMAGLMSRLLFRDM-QAADAD +RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDQKAAEAAIAEAAHSAL--- +>[subseq from] Beta-lactamase n=1 Tax=Plantibacter sp. Leaf314 TaxID=1736333 RepID=A0A0Q5EMH8_9MICO +----SAEFQALEAEFGARVGVSAIDTGSGARL-SYRADERFGYASTIKALAAAVFLHEVP +--AAAREELVTWSAEDVEAYSPVTSEHIDTGLTLSQLAEAAVRRSDNTALNLVLARIGGP +SGLDAALAALGDEVIEVVNAEPTLNVIEPGSTEDTSTPAAFADDLSRLIDGSVLEPADLE +TLLTWMSGNATGDTLIRAGAPADWPVADKSGGAG-GIRNDVAIVRPPGREPIILSIFTNK +LDPDADYDDALVAAVAKAALSAf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00090FFB71 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKQNDKLISETAKSVMKEf +>[subseq from] Uncharacterized protein n=1 Tax=Frigoribacterium sp. MCBA15_019 TaxID=1898745 RepID=A0A1S2IFB6_9MICO +--EVEAALADLETRYDARIGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLDATD +--DADLDRVVTWTQSEVDVYSPLTGQHVADGLPLRQLAEAAVRQSDNTALNLVLAELGGP +TGLDAALAAQGDDVSDVVHSEPELNTLTPGSTADTTTPAAFTATLARISDGNWLAADDRA +TLLEWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVVPPSGDPVVISVLTTR +NDPAAKYDDALVAEAARIAL--- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter cibinongensis TaxID=146475 RepID=A0A1Z5YWG7_9PROT +--QLTTALDEFEVQTGGRVGVYAKNLVTGQCL-AWRETECFLMCSTFKASLVALVLLRID +QGKEELENFVPYTQEDLGEYAPVARAHAASGMSVRSLCQGAIEQSDNVCANLLLARVGGP +TALTRFWRSLGDEVTRLDDWEPALNSTPLTEGRNTTTPATMAGSLEKILFSELLTDASRT +LLTEWLQQCRTGIKRLRLGLPQNWSVGDKTGTNGKDIAADIAVVWPVPTTPLIMSVYTRG +GHPTEQQFQSIFSNIGRLVRH-- +>[subseq from] class A beta-lactamase n=1 Tax=Acetobacter indonesiensis TaxID=104101 RepID=UPI000A3A9EC8 +-----KALADYESRTGGHIGFFAQNVVTGASL-GWRASERFVMCSTFKASLAACVLSRID +QGHDTLETTLPFSAADIKDYAPVAKANLARGLTLRDLCAGAVEQSDNVCANLLLTHIGGP +SALTAFWHALGDTTTRLDAYEPELNRTPLGRLENTTTPTAMTSVLRAITLGPALSALSRA +LLVQWMIACQTGTHRLRAGLPKHWVVGDKTGNNGKDAAGDIAVIWAKSDTPLLVSAYTRG +GKPTETDFATAFAAIGSLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=D2SSQ3_PSEAI +--DFEHAISDLEAHNQAKIGVALVS-ENGNLIqGYRANERFAMCSTFKLPLAALVLSRID +AGEENPERKLHYDSAFLEEYAPAAKRYVATGMTVTEAIQSALQLSDNAAANLLLKEVGGP +PLLTKYFRSLGDKVSRFDRIEPTLNTNTPGDERDTTTPMSMAQTVSKLIFGDTLTYKSKG +QLRRLLIGNQTGDKTIRAGLPDSWVTGDKTGSCANGGRNDVAFFITTAGKKYVLSVYTNA +PELQGEERALLIASVAKLAR--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. AEW013 TaxID=2572915 RepID=A0A560XKY5_9SPHN +--------RSIEEETGGRLGIALVDSKGALIL-GFNRDDRFALCSTFKAPLAAAVLIGAE +GGKFGLEGEIPFGKDDILDYAPVVKKNRKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP +QGLTAFMRAHGDSVTRLDRNEPALNENAPDDPRDTTTPAAMAELMGRLLFRDM-KGESAD +RLRGWLNASTTGDNRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDAKAAEAAIAQSAQAALD-- +>[subseq from] Beta-lactamase n=1 Tax=Blastomonas sp. RAC04 TaxID=1842535 RepID=A0A1B3N9D0_9SPHN +--AIARELAAIEARSGGRLGVALVGPDGHQLA-GHRADERFAMCSTFKLPLAAMVLENAH +KGRLSMADPLPVTDSDMVVYSPYVEAQRAKTVTVEGAASAAVSLSDNTAANLLLDRLGGP +QSFTAWLRGKRDSVTRLDRREPELNENALGDPRDTTTPAAMAETTRSLVVGNAMPVGQQR +LLYRWTENTTTGLKRIRGGLPQGWSAGDKTGSCGN-AFNDVAVFTAETGMRYTLAVYLDR +PAVKGDAASAIIADATRAVL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea sp. KC333 TaxID=2070368 RepID=A0A2W2DW14_9ACTN +---LTTTLRKLETSYQGRIGAVGIDLATGRTV-GYRADERFPFNSMFKVFACAAVLHKAR +TDPGLMDRVVRWKPADMAANSPETTEYTDTGMTPAQLCRAGITKSDGFAGNTLLKQIGGP +GGLTAFFRATGDRTSRLDRTEPTLTEWQPGEKRDTTTPAAAARTFAELTTGKTLHADDRA +RLVGWLKAGLTGADRIRAGLPKDWTVGDKTGTGGHGTANDVAIVWTPGSAPIILSVFTNR +NADNRPNDDKVIASTATALAK-- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Betaproteobacteria TaxID=119066 RepID=A0A0N0JEA1_9PROT +--PLQEELAALEARSGGRLGVAVLDTASGASA-GHRADTRFGLCSTFKLLLAAATIERIE +AGAWPAQRRIAYTAADLVVHSPVLRERLAEGLTALQMAQATQETSDNAAANLLMRELGGP +AGLTAWLRRQGDTLTRMDRWEPEMNIVVAGDERDTSTPAAIAATSARLLTGPVLSPAGRE +QLAGWMVATRTGARRLRAGLPAGWKAGDKTGTAMPDRYNDVAIVWPGQRAPWLLAAYFES +RHRDRPEDEAVLADVGRLV---- +>[subseq from] Beta-lactamase n=1 Tax=Pedobacter sp. PACM 27299 TaxID=1727164 RepID=A0A0P0NH37_9SPHI +-nQLRNQIKQVIAHKKADVGVSVYGIESKDTL-SVNGDRHYPMQSVFKFHIAMAVLNQVD +KGKFSLSQKIHIKKSDLLPWSPIREAHPNGELPLSEIIKYTVAKSDNNGCDILMRLLGGP +KPINDYIHSLGVKDVAIQANEEEMHKEWNVQFSNWSTPKAITQLLVKFYTENLLSKESFN +FLWTTMVETSTGVNRIKGKLPKGTIVGHKTGTSDTAAINDMGIVRLPNGKHYAIAVFVCN +TKENEATNDKIISDISKLVWDYy +>[subseq from] Class A beta-lactamase n=1 Tax=Caulobacterales bacterium RIFOXYB1_FULL_67_16 TaxID=1797588 RepID=A0A1F8IP10_9PROT +-------LSDLETRHGGRLGFAALDVGSGRRV-LWRAQERFPFCSTFKAFLAVATLERVQ +RDEERLDRAVRVTEADLIPHAPVTGAAVGRSLTLRELMQAAVEVSDNPAANILIREMGGI +AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPEQTLANIREMAFSDRLTPEHDA +LLHGWLTASPTGPNRIKAGAPEGWTVAHKTGTGANGTANDVAMLTPLSGSPVIVAAYFTG +ATATDDQRDAVIAEATRRALKAf +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Novosphingobium sp. Chol11 TaxID=1385763 RepID=UPI000BE23B11 +--------REIEKETGGRLGVALVDSKGALLL-GFNRDERFAMCSTFKAPLAAAVLMGAD +AGRFGLEGQVAFTDADILDHAPVVKANRKRGLSMAELAKAAVEVSDNSAANLLLPMIGGP +EGLTAFIRAHGDTVTRLDRTEPLLNENMEGDVRDTTSPAAMAGLIARLIFRDM-KPESAE +RLRTWLNGSTTGDKRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYLLAIYLDR +PKVDGKAADAAIAETARAALE-- +>[subseq from] Beta-lactamase n=2 Tax=Xenorhabdus bovienii TaxID=40576 RepID=A0A077PRS6_XENBV +---LKDKIKTLEAQ-GWQVGVSILDYNGNKIE-SVNGDERFPLDSTVKALACANILAKVD +NKSLRLEDSVLIKEKDIVTYSPITEGYVNKKITLKQACEATTAFSDNTAANIAISSVGGP +SELTKFMRSIGDNTTRSDRYEPDLTINPEHDLRDTTTPNAMSNSIRKLLTGNVLSEKSKE +QLKEWMMGNKVADNMLRSELPKGWFIADRSGASDYGIRGITSMVWSDKEPPLFISVYLRK +SNTSLEERSEKIAEIGMVIFSKy +>[subseq from] Beta-lactamase n=1 Tax=Oscillatoria nigro-viridis PCC 7112 TaxID=179408 RepID=K9VFX3_9CYAN +-nELRDRIEQISQAALGRVGVTATVLETGESV-TLNGDGQFPMQSVYKFPIAMAVLDRVD +RGKLKLDQKIRVEASDVLQGSRILDEKSQGMFSLSELLKYMVSESDNTSCDVLLKLLGEP +KVVTEYLRGLGVNDIVVAQTEKELAQDTAAKYRNYATPDAAVALLRAFHEGKGLSKSSQA +LLLQLMTETTTGPKRIKGLLPDGTVVAHKTGTSSTAATNDIGLVTLPNGRHLAISVFVSD +SRANDAVREEVIAKVAKAAWDEw +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia jinanensis TaxID=382504 RepID=UPI0009E7C218 +--DLANTLMMLQAKYNVLFGIAAVDPRGGRAF-GWNTDDRFAMTATFTVYAVAAILRLAE +REELDLNDKVPITRSDIVLNSPDTSYHVGELMSYYELCRATLVRSDNTAANLLLRRLGGP +AAVTEFARSIGDVQTRLDRWEPELNEAQTGDPRDTSTPAALAAGYRKLILGDGLSTEYRR +MLTSWLRSSVTSRERLRKGLPVGWVAADKSGSGAYGTANDAGVVWSPTGSSLVLVILSRS +TTPMAAGADAAVADATAAVL--- +>[subseq from] Beta-lactamase class A n=1 Tax=Bosea vestrisii TaxID=151416 RepID=A0A543N2C0_9BRAD +------DLKSLEARHGGRLGLFATR--DGQRV-GWRSTERFAFCSTFKLFLAAYVMQTVQ +QGRDRLDRDVPITAADMVPHGPVTQPAIGRTLTLEELCKATVEVSDNPAANILIREMGGL +AAFQQWYGSIDDHVTRVDRLEIELNSALPGDMRDTTTAEQYVANLDRVLRGNLLSAAHLQ +LLTRWITETPTGAGRIKAGVPAGYTVGHKTGTGARGTHNNIGIIWPPSGPSILICVFFTG +AQATPGAIDAVVADATRQAMKAf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI001128CAFD +-----SPLAEIERRNGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLERLVHYTENDLIFTSPVTKANVAHGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAVLPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio toranzoniae TaxID=1194427 RepID=A0A109D985_9VIBR +------------EKLGWSIGVTVLETDNGEKE-SIHGDKRFHFNSTIKALACANILEKSD +KNIISLDDSIKLKKGDIVTYSPVTKDYVGRNLTLKQACDATLTYSDNTAANYTISAGGGP +NGLTNFMRSIGDDVLRSDRYEPELTKNIEYDIRDTTTTNAMTSSLNKILLGNVLSDSSKK +QLRAWMEGNKVADNLLRVSLPSGWSIADRSGASDYGVRGIIALAWSESNSPVIIAMYVRK +EGTSMAERDQVIADLGHVIFDKy +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter indicus TaxID=374177 RepID=UPI001368AC7F +-----EQLEKLQASIPGILGAYIIDCESGQGF-GINENKHFALCSSFKLSLAAMVLQKAD +RGEINLDQRVHYSEGDLLSYSPVTRENLAHGLTLEELAKAAQVASDNAAANILMREFGGP +QAMTQFWRNMGDTVSRLDKTEPDLNLVAPGDEHDTTTPEAMAHTLAKLMTGTVISESSRA +KLWAWMQETSTGLQRIRGGIPKGWPAGDKTGTSFEGNYADIAFVRPPNGPPLAITSYYRL +PNKSEPQSQAVLAKVGAIAAD-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000448456F +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000D7024A1 +---------------------------------------------------------RVD +AGQEQLGRRIHYSQNDLVKYAPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Komagataeibacter hansenii TaxID=436 RepID=UPI000789B3FF +-------LSGYERATGGHVGVYAHNIATGRKL-LWRADERFVMCSTFKASLVACVLSHVD +QGRDGLDRVIPLTGADIQDYAPVAKAALAQGMSVEDMCKGAVEQSDNSCATLLLSRIGGP +PALTAFWRAMGDGTTRLDDPEPFLNRTPAGGVRDTTTPAAMAGIMQGLVLGAVLSPSSRA +LLTRWLIGCQTGKNRLRAGLPANWVVGDKTGNNARDAAGDIAVAWPHPDMPIVMCVYTRG +GTPTEPQFANVFAGVGRLVAR-- +>[subseq from] Beta-lactamase PSE-4 n=1 Tax=Photobacterium aquimaris TaxID=512643 RepID=A0A1Y6KZ77_9GAMM +--QISPELAKIEHQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TQRIDLNQAITVKQSDILSYAPVTTDRVGTSMTLAQLCNATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDKITRLDRIEPNVNNVSTAELRDTTTPIAINSTLYHLLYTDALSTSART +QLKQWMMDNKVSDPLLRAVLPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMAELNTTIANIGQLIFQH- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium shigaense TaxID=722731 RepID=A0A1Z4ELJ4_9MYCO +----DEQLATLEDRYNAKVGFHGLNLHTGRML-DYRADDLFATCSAFKAYVAGAILAKDQ +RGELSLNDPVFIDPAVLVPASTITEPHVGGYLPLSALCAASVRQSDNTATNLMVAMLGGP +GAVTEFARSTGDDRIWMVRWELELNSAYPGDPRDTSTPRSMGAGFSNMLTGDVFDDAHRA +QLWEWMSTITTGNNRIRAGLPPEWGVADKTGAGDYASTNDIGVAFGPSGERLILSIMTRT +RSEDTPALNALIADITRLAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BE2E4C +-----SPLAEIERSNGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLERLVHYTESDLIFTSPVTKANVAHGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAVLPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGSAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3P5G6W8_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSA----------------------------------------- +----------------------- +>[subseq from] Carbenicillinase n=1 Tax=Morganella morganii TaxID=582 RepID=Q307S9_MORMO +-qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPKTSTFKTIACAKLLYDAE +QGKVNPNTTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVCGP +KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK +KLESWMVNNQVTGNLLLSVLPAGWNIANRSGAGAFGARSITAVVWSEHPAPIMGSPYLAQ +TQPPMAEGNDAIVKIGHSIFDVy +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=A0A2T3MH36_PHOLE +--NIDSAIKHAEQQLGAKVGVSVLNANGDSLY-GYNSEQRFPLMSTFKTLACAKLLHDNQ +ITKGMMDKTYPVTADAILDYAPVFKDKIGTEVSLKDACFATMTTSDNSAANFVLAHIGGA +EGVTKFLIDNSDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA +QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG +TEASIPERDKEIAKIGNAIFERy +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia caledonica TaxID=134536 RepID=UPI0003AAF2D0 +---ADSPFSDIERRNGGRLGVFAIDTGSGRTL-SHRAEERFLMCSTFKGLLAAQILARVD +RGAERLDRLVHYTEKDLVFTSPVTKANVARGLPIDALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPESNRY--RGVLDTTTPTAIATTAQRLLLGDALSASSRA +QLERGMADCKPGLNRIRAVLPAGWQAADRPGTSVESETNDYALVRPPGRAPLLVAAYYDA +PGVSMEAREAVLRAAGTAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2E9CK92_9SPHN +--------RSIEEETGGRLGIALVDSKGALIL-GFNRDDRFALCSTFKAPLAAAVLIGAE +GGKFGLEGEIPFGKDDILDYAPVVKKNRKRGMSMAELAQAAVEVSDNSAANLLLPMVGGP +EGLTAFMRAHGDSVTRLDRNEPALNENAPDDPRDTXTPAAMAELMGRLLFRDM-KGESAD +RLRGWLNASTTGDNRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PTVDAKAAEAAIAQAAQAALD-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A4P8JIX7_ECOLX +-------------------GVALIETADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE +TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA +QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNE-------------------- +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A2Z6A9H0_SHISO +------------------------------------------MMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQTDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNLADHVTRLDRWEPELHQAIPNDERDTTMPAATATTSRKPLTGELLTLASPQ +QLIDWMEADKVARPLLRSALPAGWFIADKSGARERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNTQPAETGASL---- +>[subseq from] class A beta-lactamase n=1 Tax=Plantibacter sp. Leaf314 TaxID=1736333 RepID=UPI0009E9BBF9 +----SAEFQALEAEFGARVGVSAIDTGSGARL-SYRADERFGYASTIKALAAAVFLHEVP +--AAAREELVTWSAEDVEAYSPVTSEHIDTGLTLSQLAEAAVRRSDNTALNLVLARIGGP +SGLDAALAALGDEVIEVVNAEPTLNVIEPGSTEDTSTPAAFADDLSRLIDGSVLEPADLE +TLLTWMSGNATGDTLIRAGAPADWPVADKSGGAG-GIRNDVAIVRPPGREPIILSIFTNK +LDPDADYDDALVAAVAKAALSAf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Dyadobacter sp. AR-3-6 TaxID=2541721 RepID=A0A4R5DX30_9BACT +--EFAKKIETISKEARGVVGVGIMDLKSRETM-VLNPSHKFPMQSVFKFPLAMAALDQVD +KGKFILSQKIHVTRQDVSPWSPLSKKYPEGEVTLAELLSYTVSMSDNNACDILFRLLGGP +KNVEDYIRTLGVKDIAIAATEEEMSKDWNVQFTNWSRPAAMLQLLDVFFKGKKLSKESND +FLWKIMTETTTGPNRMRGLLPKEARVAHKTGTSGTAASNDVGIMTLPDGKQIAVVVYVSN +AAADEKTRDAVIAQITKAAWDYy +>[subseq from] Beta-lactamase n=1 Tax=Nostoc sp. NIES-2111 TaxID=1973475 RepID=A0A1Z4II29_9NOSO +-nELRDRLEQISQAAQGRVGITATVLETGETV-TVNGDQQFPMQSVYKFPIAMAVLAQVD +KGKLKLDQKIQIEASDIVQDSRILDENSQGRYSLAELLQYMVSESDSTACDALLRLIGEP +QRATKYLRDLGVDDIVIANTENEIQQDPSLQYRNYATPDAAVNLLRAFHQGRGLSESSQT +LLRQWMTKTSTGSNRIKALLPEGTVVAHKTGTSATAATNDVGLVTLPDGRHLAIAVFVSD +STANNAIREEVIAKVTRAVWDEw +>[subseq from] Beta-lactamase CTX-M-1 n=1 Tax=Legionella spiritensis TaxID=452 RepID=A0A0W0YX14_LEGSP +-kTLPQQLQQIEQRNSGRIGISVLNTGNQHQI-NYRANQRFPMGCTSKVIGVSAVLNKSM +TDPMLLGKKITYQTIDLASWSPVTGKHVKDGMTVEALCSAAIRYSDNTAMNLLVKELGGL +EAINAYAKQLGDHQFRQDNIWPDEAFSGGDDPYDSSSPAAMTNNLRQLLLERGLGEKQHK +LLQSWMLSNTTGDKRIRAGVPASWKVADKTGTGAYGTTNDIGVIWPGACSPIVMSVYFTQ +NHKHATPNDRVIVDVTKSVIA-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00103CB560 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKNITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Fischerella sp. PCC 9339 TaxID=1174528 RepID=UPI000362A41E +--ELYNRIEEISRTAQGRVGVALTVLETGEAV-SLNGDQRFPMQSVYKFPIGMAVLAQVD +QGKLKLEQRIRVEKNDFVSHSPIRDDNPQGVLTLAQLLKYMVSESDGTACDVLLKLVGGP +EVVMKYLRDLGINGINVINTEKEIGQDKSVQYRNWATPEAMIVLLRALHEGRGLSKSSQG +LLLRLMTETPTGLRRIKGMLPDGTVVAHKTGTSRTAATNDVGLVTLPNRQHLAIAIFVSD +STADDAAREEVIAKVARAAWDKw +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A2Z6ABP0_9SPHN +--------AEIEKETGGRLGVALVD-KTGALLlGFNRDDRFAMCSTFKAPLAAAVLTGAE +GGKFGLEGTIAFSKDDLLDYAPVVKKNLKRGMSMSELAQAAVEVSDNSAANLLLPMLGGP +PGLTAFMRAHGDAVSRLDRDEPTLNENAEGDERDTTSPAAMAGLMGRLFFRDL-AAESAD +KLRAWFNASSTGDKRIKAGLPQGWTSGSKTGTCGT-AYNDVALVKSPDGDEYILAIYLDR +PTVDAKKAEAAIAETAQAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Frigoribacterium sp. 9N TaxID=2653144 RepID=A0A653US38_9MICO +---VEAALTDLEARYDARVGLSVLDTGSGATL-DHRADERFGYASSLKAFAVAALLDATD +--DADLDRVVTWTQAEVDAYSPLTSEHVADGLPLRQLAEAAVRQSDNTALNLVLAELGGP +AGLDAALAAQGDDVTDVVHGEPELNRLTPGSTADTTTPAAFTATLARITDGDWLAADDRA +TLLEWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIATPPSGAPVVISVLTTR +NDPAAEYDDSLVAAVAEVAL--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. HH130630-07 TaxID=1690815 RepID=A0A1B1ZKE2_9PSEU +--------DGLERDFGRRIGVHILDTGSGATA-GHRDGERFLMCSVVKSLMAGFVLHRSV +SDPALLDRRVRWGPADLLEHAPTTKLHLADGLTVAQLCEAAVTVSDNTAHNLLLREVGAP +ADVTAWLRATGDTVTRADRTETDLNDV--DGELDTSTPVALAGTLAGLTTGDLLPPAQRD +RLTGWLRANTTGDGQIRAGVPAGWGVGDKTGSGPLGEKNDSGVLYPPGGAPLVLTVFTVP +GDPDDERGAEAVAATTRAAVA-- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio natriegens TaxID=691 RepID=UPI0008046428 +--KLHEDVSLLEQQISGRIGIAVWDTQTDKHW-AYRGDERFPLVGTFKTLACATMLSEMD +TGILKKNATATVEKRDMVMWSPIMDKLAGQNVRIEHACEAAMLMNDNTATNLVLNEIGGP +KSVMLFLRTIGDKATRLDSAEPSVNEAMPGDKHDTTTPNAMVNTLETLIDGDALSYESRI +QLKIWMQDSKVSDPLMRSVLPSGWSIADRSGAGGNGSLGFNAIIWKENHKPVYISIYLAE +TELSLQAREQLIAQISQLILYKy +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007CA53CB +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGREPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI000241E70C +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DA74D38 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=3 Tax=Xenorhabdus bovienii TaxID=40576 RepID=A0A077MLN0_XENBV +-----DKIKIL-EAQGWQVGVSILDYNGNKIE-SVNGDERFPLDSTVKALACANILAKVD +NKSLRLEDSVLIKEKDIVTYSPVTEGYVNKKITLKQACEATTAFSDNTAANIAISSVGGP +SELTKFMRSIGDNTTRSDRYEPDLTINPEHDLRDTTTPNAMSNSIRKLLTGNVLSEKSKE +QLKEWMIGNKVADNMLRSELPKGWFIADRSGASDYGIRGITSMVWSDKEPPLFISVYLRK +SNTSLEERSEKIAEIGMVIFSKy +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0004513FAE +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007CA1A13 +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. HIX TaxID=1759074 RepID=A0A0W1EWB2_9SPHN +-----DGLRDIEERAGGRLGFAVVDQKGRLIL-GSNDNDRFAMCSTFKLLLAGQVLRGAT +KGGPSLRTPLPFTKADIVFHSPYTEANLAAGLRLGFAAEQIVKVSDNAAANLILKATGGP +EAFTRRMREMGDEVTRLDRFETILNENAVGDPRDTTTPQAMAKSAAKIVYGDYLDPAHRQ +SLRQWMVDSQTGLGRIRAGLPAGWVAGDKTGSCGN-AYNDVAFVELPDGGKYIVAVYLDR +PKVEGAAANAIIAEVTRAIAE-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0004678E3F +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium leiognathi lrivu.4.1 TaxID=1248232 RepID=X0NN90_PHOLE +--NIDSAIKHAEQKLGAKVGVSVLNANGDSLY-GYNSEQRFPLMSTFKTLACAKLLHDNQ +ITKGMMDKTYPVTADAILDYAPVFKDKIGTEVSLKDACFATMTTSDNSAANFVLAHIGGA +EGVTKFLIDNSDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA +QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG +TEASIPERDKEIAKIGNAIFERy +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0005C275A6 +--SHAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=UPI000D726EAF +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNEKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas sp. 'scallop' TaxID=2562582 RepID=UPI0013E1F2C5 +-------LSDLEARNGGRLGFVVQDAATGRKL-GWRGDERFVYCSTFKMYLAAATLLRAQ +AGQERLDRRIPITAADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP +SAMQTFYRGIGDGSTRSDRFEPEMNRL--DGDKDTILPNQSVANLRRLFLDQALTAASRD +LLLQWMTDTPTGQNRLRAGTPANWRVAHKTGTGGYGPTNDIGLLYPPNGQPVIVAAYYHA +AQATDDANAAVIAEATRRALK-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI0008529C7B +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKRDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TKS TaxID=1315974 RepID=A0A126RMF5_9SPHN +--------KEIETETGGRLGVALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAILTGAE +GGKFGLEGQISFTKADILDYAPVVKKNGKRGMSMEELAAAAVEVSDNSAANLLLPMIGGP +EGLTMFIRAHGDTVTRLDRTEPTLNENVEGDERDTTSPAAMAGLMGRLIFRD-LKTESAG +KLRGWLNASTTGTNRIKAGLPKDWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR +PTVDAKVAEAAIAETARAALD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A7KEG3_KLEPN +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVP---------- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000D1A7DF9 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Pseudofulvimonas gallinarii TaxID=634155 RepID=A0A4S3KVZ4_9GAMM +-----DALAKLERQHGGRLGVCILDTATGAEL-RWRGDERFALCSTFKLPLAATVLRAVE +LGELDGNAPVPFGPADLVPHAPVVQARLDAGMTALELAEAAQLTSDNVAANLLLRQLGGP +AGVTESWRARGDDVTRLDRFEPAMNHVLPGEEHDTTTPCAMARHVAALVTGDLLSADSRD +LLRQWLVATDTGLRRLRAGLPPHWPAGDKTGTGIANKLNDVAVAWPPGRAPLVVAAYYES +RG--------------------- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000CD174EB +--SHTKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=2 Tax=Xenorhabdus bovienii TaxID=40576 RepID=A0A077NJK5_XENBV +-----DKIKIL-EAQGWQVGVSILDYNGNKIE-SVNGDERFPLDSTVKALACANILAKVD +NKSLRLEDSVLIKEKDIVTYSPITEGYVNKKITLKQACEATTAFSDNTAANIAISSVGGP +SELTKFMRSIGDNTTRSDRYEPDLTINPEHDLRDTTTPNAMSNSIRKLLTGNVLSEKSKE +QLKEWMIGNKVADNMLRSELPKGWFIADRSGASDYGIRGITSMVWSDKEPPLFISVYLRK +SNTSLEERSEKIAEIGMVIFSKy +>[subseq from] Beta-lactamase PSE-4 n=1 Tax=Photobacterium sp. CECT 9190 TaxID=2006084 RepID=A0A1Y6MQ87_9GAMM +--QISPELAKIEHQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TQRIDVNQAITIKQSDILSYAPVTTDRVGTSMTLAQLCNATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDKITRLDRIEPNVNNVSAAELRDTTTPIAINSTLYHLLYTDALSTSARK +QLKQWMMDNKVSDPLLRAVLPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMAELNTTIANIGQLIFQH- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DA7EEEF +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENQK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio logei TaxID=688 RepID=UPI00068489F0 +--SLNDTIIALEKQTSGDIGVAVLDTKTNQIW-SYKGNQRFPMMSTFKTLACAKMLHDAD +KKIINKKTETAIAQKDLIPWSPITEKYVGKSISTEKACEATMLMSDNTAANIVLQQIGSP +SSLTAFLLLMGDSTTQLDRIEPTLNEAKKDDIRDTTTPIAMVNTINKLLLGNTLTTTDKV +TLKKWMMDNKVSDPLLRSILPIHWSIADRSGAGGYGSRGITAIIWHEHRLPLIISIYLTQ +TDLTLAERNDIIVHVGSALFSQf +>[subseq from] Beta-lactamase n=24 Tax=Staphylococcaceae TaxID=90964 RepID=Q2FC27_STAAU +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=5 Tax=Staphylococcus aureus TaxID=1280 RepID=Q1XG18_STAAU +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000F4BE746 +---VSAELAALEAEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKALAAAEFLRSVP +--VGERDEVVTWTAADVEAYSPVTSESIDGGLPLAQLAEAAVRRSDNTALNLVLDRLGGP +AALDRALEQLGDTTTDVVDEEPALNTIAPGGTANTTTPAAFTADLTAVALGEALPSADRA +LLLDWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDIAVVTPPGRDPIVLSVLTSR +NDPEADYDDALVARAAAVVL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000E10331B +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYLPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio natriegens TaxID=691 RepID=UPI0008040581 +--KLHEDVSLLEQQISGRIGIAVWDTQTDKHW-AYRGDERFPLVGTFKTLACATMLSEMD +TGILKKNATTTVEKRDMVMWSPIMDKLAGQNVRIEHACEAAMLMNDNTATNLVLSEIGGP +KSVMLFLRTIGDKATRLDSAEPSVNEAMPGDKHDTTTPNAMVNTLETLIDGDALSYESRI +QLKIWMQDSKVSDPLMRSVLPSGWSIADRSGAGGNGSLGFNAIIWKENHKPVYISIYLAE +TELSLQAREQLIAQISQLILYKy +>[subseq from] Beta-lactamase n=3 Tax=Sphingomonadaceae TaxID=41297 RepID=T0HJ78_9SPHN +--------KMIEEETGGRLGVALVDSSGALIL-GFNRDERFAMCSTFKAPLAAAILLGAE +GGKFGLEGQVSFTKDDVLPYAPVVKQNLKRGLSMEELAAAAVEVSDNSAANLLLPMVGGP +EGLTAFFRAYGDTVSRLDRKEPDLNENEPGDPRDTTSPAAMAALMARLIFKDM-KPQSAE +KLRTWLSRSKTGDRRIKAGLPEGWTSGGKTGSCGT-AYNDVALVKSPSGAEYLLAIYLDR +PAVDEAKADAAIAETAASALD-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000E3E70C0 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Bacillales TaxID=1385 RepID=UPI0004B12182 +---HAEELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia caribensis TaxID=75105 RepID=UPI0007201058 +----DSPVSDIERRNGGRLGVFAIDTGSGRTL-SHRAEERFLMCSTFKGLLAAQILARVD +GGAERLDRLVHYTEKDLVFTSPVTKANVARGLSIDALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPESNRY--RGVLDTTTPKAIATTAQRLLIGDALSASSRA +QLERGMADCKPGLNRIRAVLPAGWQAADRPGTSVESETNDYALVRPPGRAPLLIAAYYDA +PGVSMEAREAVLREAGTAFV--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000E093A21 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGKEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007697A91 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=A0A1W5QCF3_9STAP +---SAQDLTKLEHKNDATVGVYGINTATGKTY-SHNADTRFAYASTFKAITSGLLLQQSS +--PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNVIMEQLGGL +DQISSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHSLQQLLTTDAVAPQQRK +FLQNLMFNNETGDSLIKKGVPDSYKVGDKSGQGTYGTRNDVALIYPKHQKPIVLVVFTKH +KQQDAKPQDALVAQAARQAIQ-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012B05A44 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKNGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0013E2E7ED +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Phycosocius bacilliformis TaxID=1445552 RepID=A0A2P2ECY7_9PROT +-qTAAKSLKALEAEAGGRLGVSILDTSNGELV-GHRQNERFALCSTFKLILAAEVLRDID +LGLLQRDQFVSYNQSDMVPHAPVTQAHLAEGMRLIDLARATQVTSDNPAANLLIRLLGGP +QAVTRRFREAGDRVTRLDRYEPMLNLVEPGSQFDTTSPAAMARLVARYLIGDYLSDLAKR +SLTGWLVETTTGLRRIRAGLPSGWRAGDKTGTVVQDFYNDVAIIWPPSHRPLIVAAYYNP +AVSSNPLHEAVLASVGRIAT--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0009100B1F +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQCLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00123E47F5 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=C6KFE1_PSEAI +--DFEHAISDLEAHNQAKIGVALVS-ENGNLIqGYRANERFAMCSTFKLPLAALVLSRID +AGEENPERKLHYDSAFLEEYAPAAKRYVATGMTVTEAIQSALQLSDNAAANLLLKEVGGP +PLLTKYFRSLGDKVSRLDRIESTLNTNTPGDERDTTTPMSMAQTVSKLIFGDTLTYKSKG +QLRRLLIGNQTGDKTIRAGLPDSWVTGDKTGSCANGGRNDVAFFITTAGKKYVLSVYTNA +PELQGEERALLIASVAKLAR--- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium amiense TaxID=135719 RepID=UPI000A06963C +--------KEIEAETGGRLGVALVDSKGALLL-GFNRDERYPMCSTFKAPLAAAVLVGAE +GGKFGLEGTIPFGKEDVLDYAPAVKKNLKRGMSMAELAQAAVELSDNSAANLLLPMLGGP +EGLTAFMRAHGDTVSRLDRTEPELNENAEGDPRDSTSPAAMAGLMARLIFNDM-KPESAT +KLRGWLNGSSTGDRRIKAGLPEGWTSGSKTGSCGT-AYNDVALVRSPGGDEYILAIYLDR +PTVDAKKAEAAIAETARAAL--- +>[subseq from] Beta-lactamase n=2 Tax=Staphylococcus TaxID=1279 RepID=D2JC69_STAEP +--SHTQELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQHLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. OK269 TaxID=2135728 RepID=A0A3D9TFK9_9NOCA +-------FGELEQREQARLGVYAIDLESGASI-DYRSNERFAFCSTFKVYAAGAVLAAVD +SGQLALTDTRTVTAASKVAESAVD-WPVDSAVTLGEFCAAALGRSDNTSGNFLIDAAGGT +AAVTEFARSLGDTEFRLDRTEPELNTAIPGDDRDTTTPESLGAGYRALLRGDVLADSWRD +QLLAWMGDTHTSDMRFRAGIPAGWTSADKTGTGSYGVSNDAGLLLGPDGREILLVVLSTT +TTSDAAAMNSLVADTTREVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Microbacteriaceae bacterium 3R27F9-B TaxID=2502222 RepID=UPI0010FA46BC +--EVEAALADLETRYDARIGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLDATD +--DADLDRVVTWTQAEVDAYSPLTSTHVADGLPLRQLAEAAVRQSDNTALNLVLAELGGP +AGLDAALAAQGDDVTDVVHSEPELNRLTPGSTADTSTPAAFTATLARITDGDWLAAHDRA +TLLEWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVVPPSGDPVVISVLTTR +NDPAATYDDALVAAVAEVAL--- +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium amiense TaxID=135719 RepID=A0A494VZP4_9SPHN +--------KEIEAETGGRLGVALVDSKGALLL-GFNRDERYPMCSTFKAPLAAAVLVGAE +GGKFGLEGTIPFGKEDVLDYAPAVKKNLKRGMSMAELAQAAVELSDNSAANLLLPMLGGP +EGLTAFMRAHGDTVSRLDRTEPELNENAEGDPRDSTSPAAMAGLMARLIFNDM-KPESAT +KLRGWLNGSSTGDRRIKAGLPEGWTSGSKTGSCGT-AYNDVALVRSPGGDEYILAIYLDR +PTVDAKKAEAAIAETARAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Citricoccus muralis TaxID=169134 RepID=A0A3D9LA08_9MICC +--STDRALTDLEERFSGRVGVYAVDTGTGEEV-QYRADERFGYASTHKVFSAAAVLAQSE +--PADLDQRIHYSAEDLVANSPIAEQHVETGMTLGQIIGAAISHSDNTAGNLLFDALGGP +EGLQDAVVRTGDETTSVDREEPELNEWAPGETRDTTTPRQAAENLRGYTLGDTLEPWARD +ELLAAMRASENSEGLIRAAVPASWTVGNKSGAGGHGTRNDLAVIERAEGAPLVVAVYTNL +DDPEGQFQDDFVAEAATVAVE-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00067CDCED +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A6B5HUE4_STAAU +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVIKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI00094B9A91 +--SHAQELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQHLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_036 TaxID=2175620 RepID=A0A2W1W4F8_9MICO +--RVDRALAALEQRYDATVGVVATDTGTGATV-SYRADRRFGYASTIKVLAAAAFLRAVP +--AAERSAVAHWTQADVAAYSPVTEQHVADGLPLDEVAEAAVRMSDNTALNVLLDRIGGP +AALDAALADLGDTTTEVVHDEPELNTIEPGSTEDTTTPAAFAAVLDRVLDGRTLGRADTA +LLTDWMSGNATGDALVRAGAPDGWVVADKSGGAGP-IRNDVARVTRPDGDPIVIAVLTTR +NDPDEPYDEALVAESARVAL--- +>[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A6B5G9D2_STAAU +--SHTKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=5 Tax=Staphylococcus TaxID=1279 RepID=A0A6B5HE94_STAAU +--SHTKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=18 Tax=Bacteria TaxID=2 RepID=E4PYK2_STAAU +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0002CC334D +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000852EAFC +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=69 Tax=Bacteria TaxID=2 RepID=BLAC_STAAU +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0005C7B221 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus sp. HMSC58E11 TaxID=1608881 RepID=UPI0008A86526 +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus caprae TaxID=29380 RepID=UPI000BA55854 +--SHTKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKTLIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio sp. dhg TaxID=2163016 RepID=A0A3B7D7C4_9VIBR +--KLHEDVSLLEQQISGRIGIAVWDTQTDKHW-AYRGDERFPLVGTFKTLACATMLSEMD +TGILKKNATATVEKRDMVMWSPIMDKLAGQNVRIEHACEAAMLMNDNTATNLVLSEIGGP +KSVMLFLRTIGDKATRLDSAEPSVNEAMPGDKHDTTTPNAMVNTLETLIDGDALSYESRI +QLKIWMQDSKVSDPLMRSVLPSGWSIADRSGAGGNGSLGFNAIIWKENHKPVYISIYLAE +TELSLQAREQLIAQISQLILYKy +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000A3265ED +---HAKELNDLEKKYNAHIGVYALDTKNGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DA84A61 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHIDKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DAA312B +---HSKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Clavibacter sp. CFBP 8615 TaxID=2301718 RepID=A0A399T5W3_9MICO +--DVSAELQALEGEFDARVGVSVLDTGTGDSV-AYRSDERFGYASTLKLFAAAELLHDVP +--ADQRDEIATWSAADMEEYSPVTSAHVDTGLPLAQLAEAAMRESDNTAMNVILERIGGP +AGLDRALEELGDTTTEVVNREDELNRIEPGSTDDTTTPAAFTGALAGILRGDRLSDHDRA +ILLDWMSGNATGDALIRAGAPDGWTVADKSGGAG-AIRDDIAVVTPPGRDPLVVTILTTR +NDPERDHDDALVARAAEVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. DL592 TaxID=2675524 RepID=UPI00141F0DEA +---LNERIGMLESRHNAVVGLYGENLDAKQTV-AHREGDMFAVCSTFKAYLAARILQKAQ +HGELRMMDTLRVDPAAVLPNSPISGPKAGSSLPLDELCQAVLQRSDNTAANMLLTVIGGP +QAITAFARSIGDDRTRLDRWETELNSALPGDPRDTSTPRTLGGGFRAILTGDVLDPAHRR +QLEDWMRGNVT--SSMRAGLQPGWTSADKTGSGDYASTNDIGIVFGPNGERILLAVMTRT +RSPNAEPLRQLIAEVTTAA---- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=UPI000D72AC9E +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQAP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=57 Tax=Bacteria TaxID=2 RepID=D2JLJ2_STAAU +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0004B61EAE +---HATELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00124EFA79 +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYETELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Aeromonas dhakensis TaxID=196024 RepID=UPI000F5293E8 +-----------------------------------------PLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSALPGDARDTSPPRAVTERLQKLTLGSAPAAPQRQ +QIVGWPQGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus TaxID=1279 RepID=UPI000447F1B5 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=UPI00069D1AAA +---HAKELNDLEKKYNAHIGVYALDTKSGKKV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000766D6C7 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKNDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas ginsenosidivorax TaxID=862135 RepID=A0A5C6ULI2_9SPHN +---AMDEISALERRYGGRLGVFALDLETGRTF-AHRKDQRFKLQSTFKGLLAALVLADVS +RGAEKLDGIVHFGKADLLPASPVTEDAVARGMTVRELCEAIMYRSDNTAANLLMTRRGGP +DRLTRFLRGLGDDVTRTDSYEGHMNGR--PAAFDTTSPQAIVKTVRTLLLGSALPPSSQR +QLETWMEGNVVGRTRLRAAFPSDWRSGDRTGTGD-GVCNDYAIARRPGRAPLVMSAYYAA +PGMRLLDQEAVIRSVGRTVVE-- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. DS20 TaxID=1532555 RepID=A0A0P0CZ11_9CAUL +-------LNDLETRWGGRLGVAALDVGSGVRA-LWRSQERFPFCSTFKPFLAAAVLQRVQ +RDEERLDRPVRITSADIIPHAPVTEKAVGRTLTIRELMQAAVEVSDNPAANILIREMGGI +GVWRSWWPTFGDTTTVISRLEPDLNTALPDDPRDTCLPEQTVANIREMAFSDRLTPAHDA +LLHGWLTASPTGPNRIKAGAPEGWSVAHKTGSGARGTTNDVGMLTPLSGSPVIIAAYFTG +AAATEDQRDAVIAEATRRVLK-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Larkinella soli TaxID=1770527 RepID=UPI000FFB16B1 +--ALEKEIQRIAAAAQGKVGIAAVVIETGKTV-SLNGDDRFPMQSVYKMPIGMAVLRAVD +QGRLKLDQKVPVTKADYVGHSPLRDAHPNGTTTVRELLRYNVLESDGSACDVLLRLIGGG +PAVTAYLEQNGVKGVRVINTEKEIGSAEDVQYRNWATPNEALALLKLLHQGGSLSAESRK +LMLKLMTDTQTGLKRIRGLLPPGTAVAHKTGTSQTAATNDIGIVTLPDGRHLAIAVFVSD +ARAGSEQREKVIAEISKAVWDAw +>[subseq from] Beta-lactamase class A n=1 Tax=Novosphingobium sp. GV027 TaxID=2135689 RepID=A0A2T6LVZ1_9SPHN +------PMAEYERTTGGRIGVHALNVTTGQTL-TWRADERFIMCSSYKASLAAFVLARVD +RGEEKLDALVPYTAQDTLGWGPIAKENLAKGMTVAAMCKAAVEISDGVCANMLMARSGGP +AALTAFLRSIGDTRTRVDHFEPALDRVPSGGPDDSTTPAAMASTLQKVVLGDVLAARSKG +LLTRWLIGNQT-NPRLRGGLPQSWRIANKTGHSGQDMAGDIAVAWPHPELPIVIAVYTRG +GRPTEAQFDKAFAGIGRLVAS-- +>[subseq from] Beta-lactamase n=2 Tax=Cellulomonas carbonis TaxID=1386092 RepID=A0A0A0BQJ3_9CELL +---------------------FAVDTASGLTV-EHRADERFGYASTHKALSVAALLAELA +--PAELDAVVRWTADDVVAHSPVTQERTGTGMTWRELGAAAVTHSDNTAANLVLDRLGGP +AGFERALRDLGDDVTSADRVEAALNEVAPGDARDTTTPRALAAGLRSYLLDGALTPEDAH +LLLGWMRDSTTGAGLVRAGVPAGWDVADKSGGGSYGIRNDVAVVRPPGGEPVVIAVMTAK +DERAAEGDDALVARATEVVVQH- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A192Y4S5_PSEAI +--DFEHAISDLEAHNQAKIGVALVS-ENGNLIqGYRANERFAMCSTFKLPLAALVLSRID +AGEENPERKLHYDSAFLEEYAPAAKRYVATGMTVTEAIQSALQLSDNAAANLLLKEVGGP +PLLTKYFRSLGDKVSRLDRIEPTLNTNTPGDERDATTPMSMAQTVSKLIFGDTLTYKSKG +QLRRLLIGNQTGDKTIRAGLPDSWVTGDKTGSCANGGRNDVAFFITTAGKKYVLSVYTNA +PELQGEERALLIASVAKLAR--- +>[subseq from] Class A beta-lactamase n=1 Tax=Vibrio natriegens TaxID=691 RepID=A0A1B1EJP6_VIBNA +--KLHEDVSLLEQQISGRIGIAVWDTQTDKHW-AYRGDERFPLVGTFKTLACATMLSEMD +TGILKKNATATVEKRDMVMWSPIMDKLAGQNVRIEHACEAAMLMNDNTATNIVLSEIGGP +KSVMLFLRTIGDKATRLDSAEPSVNEAMPGDKHDTTTPNAMVNTLETLIDGDALSYESRI +QLKIWMQDSKVSDPLMRSVLPSGWSIADRSGAGGNGSLGFNAIIWKENHKPVYISIYLAE +TELSLQAREQLIAQISQLILYKy +>[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea sp. p1410 TaxID=2603600 RepID=UPI0012FA7295 +--ALQRRLRALEGAYEGRIGAVAIDLATGRTV-GYRAGERFPFNSMFKVYACAAVLAKAR +RDPGLMDRIVRWQPGEVMDNGPETKEYTDTGMTPAQLCRAGITKSDGLAGNLLLKQIGGP +SGLTGYFRSIGDRTSRLDRFEPHLTEWKPGEQRDTTTPEAAARSFTRITTGDALDTRDRE +RLVAWLRDSVTGAERIKAGLPKTWTVGDKTGTGGHGTANDVAIAWPPGAQPIIISVLTNR +TANGLPADQKVIAKTATALAK-- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=A0A1W5QH29_9STAP +----AQGLTKLEHKNDATVGVYGINTATGQTY-SHNADTRFAYASTFKAITSGLLLQQSS +--PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNIIMEQLGGL +DQISSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHSLQQLLTTDAVAPQQRK +FLQNLMFNNETGDSLIKKGVPDSYKVGDKSGQGTYGTRNDVALIYPKHQKPIVLVVFTKH +QQQDAQPQDELVAQAARHAIH-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus pettenkoferi TaxID=170573 RepID=UPI00119D66B3 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQHLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=A0A1W5QBZ5_9STAP +----AQGLTKLEHKNDATVGVYGINTATGQTY-SHNADTRFAYASTFKAITSGLLLQQNS +--PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNIIMEQLGGL +DQLSSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHNLQKLLTTDAVAPQQRK +FLQNLMFNNKTGESLIKKGVPNSYKVGDKSGQGTYGTRNDVAVIYPKHQKPIILVVFTKH +QQQDAQPQDELVAQAARHAIH-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium limneticum TaxID=1007511 RepID=A0A5J5I6S2_9SPHN +--------AEIEKETGGRLGVALVD-KTGALLlGFNRDDRFAMCSTFKAPLAAAVLTGAE +GGKFGLEGTIAFSKDDLLDYAPVVKKNLKRGMSMSELAQAAVEVSDNSAANLLLPMLGGP +PGLTAFMRAHGDAVSRLDRDEPTLNENAEGDERDTTSPAAMAGLMGRLFFRDL-AAESAD +KLRAWFNASSTGDKRIKAGLPQGWTSGSKTGTCGT-AYNDVALVKSPDGDEYILAIYLDR +PTVDTKKAEAAIAETAQAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter festucae TaxID=110937 RepID=UPI0013191E81 +---VSAELAALEAEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKALAAAEFLRSVP +--ADERDEVVTWTAADVEAYSPVTGESIDGGLSLAQLAEAAVRRSDNTALNLVLDRLGGP +AALDRALEQLGDTTTDVVDEEPALNTIAPGSTANTTTPAAFTADLAAVALGEALPSADRA +LLLDWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDVAVVTPPGRDKIVLSVLTSR +NDPEAAYDDALVARAAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Gemmobacter sp. HB-1 TaxID=2652247 RepID=UPI00124CB56A +--DLGATITRLETDLEARIGIQILDTATGWSW-GHRQDERFLMASTFKSVLCGGILQGVD +RGEISLEESVRIGAQ-VPRNSPVTSRYLGGSLSIARLCLATLDQSDNGAANLLIDRMGGT +QAVTAFLRGIGDSVTRLDRKEPEMNLFLPGDPRDTTSPAAMVASWQVLLTGDALAPASRA +QLIEWMSIGGVTGTLLRPSVPPGWQVADRSGGGRDHTRNIVAMLTPPGRAPFFVAIYLSD +TPANWSTRNAAVAELSAKA---- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0011401E82 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHVNKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Microbacteriaceae bacterium J5903 TaxID=2528712 RepID=UPI001239F20F +--DVSRELQRLETEYDATIGVSAGEPATGRSV-AYRPDTRFGYASTIKLFVAAEFLRRVP +--ADDRKDVVTWSAGDVKAYSPVTADHVSTGLSLENLAEAAVRESDNTATNVLLDRIGGP +GGLDAALAQWGDDTTHVARAEPALNEVDLGRTDDTTTPAAFTGNLTQLLNGPILPPDDRA +LLLEWMSGNATGDALIRAGAPAGWTVADKSGGAGP-MRNDIAVVTPPGGDPLVLTVLTRR +NDASAAYDDALVAEVAAVVLSAf +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter indonesiensis 5H-1 TaxID=1231340 RepID=A0A0D6N9I5_9PROT +-----KALADYESRTGGHIGFFAQNVVTGASL-GWRASERFVMCSTFKASLAACVLSRID +QGHDTLETTLPFSAADIKDYAPVAKANLARGLTLRDLCAGAVEQSDNVCANLLLTHIGGP +SALTAFWHALGDTTTRLDAYEPELNRTPLDRLENTTTPTAMTSVLKAIALGPALSALSRA +LLVQWMIACQTGTHRLRAGLPKHWVVGDKTGNNGKDAAGDIAVIWAKSDTPLLVSAYTRG +GKPTETDFATAFAAIGSLVA--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000CD0C8A1 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFSKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] ARL family class A beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=UPI00028240B9 +----AQGLTKLEHKNDATVGVYGINTATGQTY-SHNADTRFAYASTFKAITSGLLLQQNS +--PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNIIMEQLGGL +DQISSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHSLQQLLTTDAVAPQQRK +FLQNLMFNNETGDSLIKKGVPDSYKVGDKSGQGTYGTRNDVALIYPKHQKPIVLVVFTKH +QQQDAQPQDELVAQAARHAIH-- +>[subseq from] Beta-lactamase n=1 Tax=Geitlerinema sp. PCC 7407 TaxID=1173025 RepID=K9S819_9CYAN +---LRDLLNEIAQAAQGRVGMTATVLESGESV-SLNGNERFPMQSVYKLPIAMAVLNQVD +QGNLKPDQKIRIEASDIVQGSQVLDENSQGKFSLSELLQYMVSESDNTACDVLLRLIGEP +QRVTEYLSSLGINDIVVANTEQELAQDPAVQYRNFATPDAAAVLLRTLQEGRGLSQSSQA +LLLQWMTETPTGLKRIKGLLPEGTVVAHKTGTSATAATNDVGLVTLPSGQHLAIAVFVSD +SQAADVIREEVIARMAKAAWDEw +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. Leaf26 TaxID=1735693 RepID=A0A0Q4JFT1_9SPHN +------NPAEIEKETGGRLGVALVD-KTGALLlGFNRDDRFAMCSTFKAPLAAAVLIGAS +AGKFGLEGTIPFSGDDILDYAPVVKKNKKRGMSMGELAQAAVEVSDNSAANLLLPLLGGP +EGLTAFMRAHGDTVSRLDRNEPTLNENAEGDPRDTTSPAAMAGLMGRLFFRDM-KQESAE +TLRTWFNASSTGDKRIKAGLPQGWTSGSKTGTCGT-AYNDVALVHAPSGDEYILAIYLDR +PTVDAKKAEAAIAETAQAAL--- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=A0A1W5QE54_9STAP +----AQGLTKLEHKNDATVGVYGINTATGKTY-SHNADTRFAYASTFKAITSGLLLQQSS +--PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNIIMEQLGGL +DQISSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHSLQQLLTTDAVAPQQRK +FLQNLMFNNETGDSLIKKGVPDSYKVGDKSGQGTYGTRNDVALIYPKHQKPIVLVVFTKH +QQQDAQPQDELVAQAARHAIH-- +>[subseq from] Beta-lactamase CARB-6 n=2 Tax=Vibrio sp. THAF100 TaxID=2587862 RepID=A0A5P9CPV8_9VIBR +--SLEQSLSKIEQEIKGQVGVAVIDTQSHNQW-SYNGNQRFPMMSSFKTLACAKLLYDVE +QKKLTLSQKIDVPESGLVNWNPITENFVGSKMSLQSVCAATMLMSDNYAANLALQQIGGP +SGLTAFLREIGDQKTRLDRYEPELNYVEKGAENDTTTPIAITQTIKRLLTGDVLSTGSKT +QLQFWMTNNMISDSLARSVLPQGWLIADRSGGGVKGSRALTAMVWKSDRKPLFIGIFIAN +SSSTLPEINQVVADISQLIFAQy +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012ED141E +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A2D8FS96_9CAUL +-------LNDLETRWGGRLGVAALDVGSGVRT-LWRSQERFPFCSTFKPFLAAATLQRVQ +RDEERLDRPVRITSADIIPHAPVTEKAVGRTLTIRELMQAAVEVSDNPAANILIREMGGI +GVWRSWWPTFGDTTTVISRLEPDLNTALPDDPRDTCLPEQTVANIREMAFSDRLTPAHDA +LLQDWLTASTTGPGRIKAGAPEGWSVAHKTGSGANGTTNDVGVLTPLSGSPVIIAAYFTG +AAATEDQRDAVIAEATRRALK-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI000B593E32 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSIMKEf +>[subseq from] Beta-lactamase n=2 Tax=Rathayibacter oskolensis TaxID=1891671 RepID=A0A1X7PJL5_9MICO +---VSADLRALEAEFDARVGVSAVDTGSGAAI-THRADERFGYASTIKALAAAEFLHDVP +--VDQRDEIVTWSADDVEAYSPVTSQHVDGGLPLSELAEAAVRTSDNTALNLVLDRIGGP +TALDEGLTELGDDTTEVVDDEPALNVIEAGSTDDTSTPAAFTADLARILEGDRLTEEDRA +TLLDWMSGNATGDALIRAGTPSGWVVADKSGGAG-GTRNDLAVVTPPGRAPIVVTVFTSR +NDPEREYDDSLVARTAEIVL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=UPI00069E49F8 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTLKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0004450649 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044FC9FB +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] class A beta-lactamase n=1 Tax=Acinetobacter TaxID=469 RepID=UPI0005C5B5A9 +---LEEQVKSL-SEKGWQVGVSILDME-NKRI-SINGDKRFPLDSTVKALACAHVLAQVD +AKKLTLDHSKTIRQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP +AGLTSFMRSIGDEVTRSDRYEPDLVINPEGDIRDTTSPNAMNDSMKKLLMDDVLSKSSKE +QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGITSMVWSENHAPVFISIYVRK +SETSLDERSAVIKLLSEHIVKE- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter colistiniresistens TaxID=280145 RepID=A0A558ERX5_9GAMM +---LEEQVKSL-SEKGWQVGVSILDME-NKRV-SINGDKRFPLDSTVKALACAHVLAQVD +AKKLTLDHSKTIRKKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP +AGLTSFMRSIGDEITRSDRYEPDLVINPEGDMRDTTSPNAMSDSMKKLLMGDVLSKSSKE +QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGITSMVWSENHAPVFISIYVRK +SETSLDERSAVIKLLSEHIVKE- +>[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea sp. C10 TaxID=2600577 RepID=A0A5C8JRW2_9ACTN +--ELDKTLRELEKTYDGRIGAVGIDLATGRTV-GYRAGERFPFNSSFKVFACAAVLHKAR +TAPGLMDKVIRWKPADMAENSPETTEYTDTGMTPAQLCRAGITKSDGFAGNTLLKQIGGP +PGLTRFFRATGDRTSRLDRTEPTLTHWAPGEKRDTTTPAAAARTFAELTTGKTLHAQDRA +RLVGWLKASLTGANRIKAGLPKDWTVGDKTGTGGHGTANDLAIVWTPGSAPIILSVFTNR +NDDDTPHDDKVIASAATALAK-- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. G8 TaxID=1350776 RepID=A0A653NCX8_9CAUL +-------LNDLEELNGGRLGVAALDVGSQRRV-SWRGQERFAFCSTFKAFLAVATLERVQ +REEEQLDRAVAVTRADMIPHAPVTEKAIGRTLTIRELMQAAVEVSDNPAANILIREMGGI +AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPDQTIANIRELAFSDRLTPAHDQ +LISGWMIASPTGANRIKAGAPEGWTVAHKTGTGANGATNDIGMLTPLSGSPVLLAAYFTG +APATDDQRDAVIAEATRRALK-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000F478506 +---VSAELAALEAEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKALAAAEFLRSVP +--ADERDEVVAWTAADVEAYSPVTSESIDGGLPLAQLAEAAVRRSDNTALNLVLDRLGGP +AALDRALEQLGDTTTDVVDEEPALNTIAPGSTANTTTPAAFTADLTAVALGEALPTADRA +LLLDWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDVAVVTPPGRDPIVLSVLTSR +NDPEAAYDDALVARAAAVVL--- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=A0A1W5QG57_9STAP +----AQGLTKLEHKNDATVGVYGINTATGQTY-SHNADTRFAYASTFKAITSGLLLQQNS +--PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNIIMEQLGGL +DQLSSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHNLQNLLTTDAVAPQQRK +FLQNLMLNNKTGESLIKKGVPNSYKVGDKSGQGTYGTRNDVAVIYPKHQKPIILVVFTKH +QQQDAQPQDELVAQAARHAIH-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=7 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044A4E95 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium leiognathi subsp. leiognathi TaxID=658 RepID=B0KYV0_PHOLE +--NIDSAIKHAEQQLGAKVGVSVLNANGDSLY-GYNSEQRFPLMSTFKTLACAKLLHDNQ +ITKGMMDKTYPVTADAILDYAPVFKDKIGTEVSLKDACFATMTTSDNSAANFVLAHIGGA +EGVTKFLIDNSDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA +QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG +TEVSIPERDKEIAKIGNAIFERy +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00066DE950 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00129DD9EA +--SHAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYIGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio natriegens TaxID=691 RepID=UPI0003580C2A +--KLHEDVSLLEQQISGRIGIAVWDTQTDKHW-AYRGDERFPLVGTFKTLACATMLSEMD +TGILKKNATAIVEKRDMVMWSPIMDKLAGQNVRIEHACEAAMLMNDNTATNLVLSEIGGP +KSVMLFLRTIGDKATRLDSAEPSVNEAMPGDKHDTTTPNAMVNTLETLIDGDALSYESRI +QLKIWMQDNKVSDPLMRSVLPSGWSIADRSGAGGNGSLGFNAIIWKENHKPVYISIYLAE +TELSLQAREQLIAQISQLILYKy +>[subseq from] Class A beta-lactamase n=1 Tax=Photobacterium aquimaris TaxID=512643 RepID=A0A2T3HWI6_9GAMM +--QISPKLAKIEHQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TQRIDLNQAITIKQSDILSYAPVTTDRVGTSMTLAQLCNATMLTSDNTAANLVLNNIGGP +KSVTQFIRTLDDKITRLDRIEPNVNNVSTAELRDTTTPITINSTLYHLLYTDALSTSART +QLKQWMMDNKVSDPLLRAVLPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMAELNTTIANIGQLIFQH- +>[subseq from] class A beta-lactamase n=1 Tax=Frigoribacterium sp. Leaf8 TaxID=1735673 RepID=UPI0006FD5338 +--EVEAALTDLETRYDARVGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLDATD +--DADLDRVVTWTQAEVDAYSPLTSEHVADGLPLRQLAEAAVRKSDNTALNLVLTELGGP +AGLDAALAAQGDDVTDVVHGEPELNTLTPGSTADTTTPASFTATLARITDGDWLAADDRA +TLLEWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVVPPSGDPVVISVLTTR +NDPAATYDDALVAAVAEVAL--- +>[subseq from] Uncharacterized protein n=1 Tax=Photobacterium carnosum TaxID=2023717 RepID=A0A2N4UMG5_9GAMM +--QITPELTNIEQHLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TKRVDLNQPIMINQSDILSYAPVTADRVGTSMTLAQLCNATMLTSDNTAANLVLNNIGGP +QSVTQFIGTLDDKTTRLDRIEPEVNNVSKAELRDTTTPIAMNSTLYNLLYGHTLSETARI +QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDNYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMADLNTTIAKIGQLIFTH- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0004528CBD +--SHAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Plantibacter TaxID=2624265 RepID=UPI0009E8C0D2 +----SAEFQALEAEFGARVGVSAIDTGSGARL-SYRADERFGYASTIKALAAAVFLRQVP +--AAAREELVTWSAEDVEAYSPVTSEHIDTGLTLSQLAEAAVRRSDNTALNLVLARIDGP +SGLDAALAAFGDEVIEVVNAEPTLNVIEPGSTEDTSTPAAFADDLSRLIDGSVLEPADQE +TLLTWMSGNATGDTLIRAGAPADWPVADKSGGAG-GIRNDVAIIRPPGREPIILSIFTNK +LDPDADYDDALVAAVAKAALSAf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=UPI000E26EF36 +--SHTKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. QXT-31 TaxID=1357916 RepID=A0A1P8WUJ6_9SPHN +-----DGLRDIEERAGGRLGFAVVDHKGRLIL-GSNDNDRFAMCSTFKLLLAGQVLRGAT +RGGPSLRTPLPFTKADIVFHSPYTEANLASGLRLGFAAEQIVKVSDNAAANLILKATGGP +EAFTRRMREMGDAVTRLDRFETILNENALGDPRDTTTPQAMAKSAAKIVYGDYLDPAHRK +SLRQWMVDSQTGLGRIRAGLPAGWVAGDKTGSCGN-AYNDVAFVELPDGGKYIVAVYLDR +PKVEGAAANAIIAEVTRAIAE-- +>[subseq from] Beta-lactamase n=3 Tax=Staphylococcus TaxID=1279 RepID=U1EQ46_9STAP +----AQGLTKLEHKNDATVGVYGINTATGQTY-SHNADTRFAYASTFKAITSGLLLQQNS +--PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNIIMEQLGGL +DQISSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHSLQQLLTTDAVAPQQRK +FLQNLMFNNETGDSLIKKGVPDSYKVGDKSGQGTYGTRNDVALIYPKHQKPIVLVVFTKH +QQQDAQPQDELVAQAARHAIH-- +>[subseq from] Beta-lactamase n=1 Tax=Komagataeibacter hansenii ATCC 23769 TaxID=714995 RepID=D5QCA1_KOMHA +-------LSGYERATGGHVGVYAHNIVTGRKL-LWRADERFVMCSTFKASLVACVLSHVD +QGRDGLDRVIPLTGADIQDYAPVAKAALAQGMSVEDMCKGAVEQSDNSCATLLLSRIGGP +PALTAFWRAMGDGTTRLDDPEPFLNRTPAGGVRDTTTPAAMAGIMQGLVLGAVLSPSSRA +LLTRWLIGCQTGKNRLRAGLPANWVVGDKTGNNARDAAGDIAVAWPHPDMPIVMCVYTRG +GTPTEPQFANVFAGVGRLVAR-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044AD3E1 +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. PhB127 TaxID=2485176 RepID=UPI000F4B3EAF +---VSAELAALEAEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKALAAAEFLRSVP +--ADERDEVVTWTAADVEAYSPVTGESIDGGLPLAQLAEAAVRRSDNTALNLVLDRLGGP +VALDRALEQLGDTTTDVVDEEPALNTIAPGSTANTTTPAAFTADLTAVALGEALPAADRA +LLLDWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDVAVVTPPGRDPIVLSVLTSR +DDPEADYDDALVARAAAVVL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00006E623E +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A1B1W3B6_ACIBA +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia tropica TaxID=92647 RepID=A0A1H7ER90_9BURK +---ADSPFSDIERRNGGRLGVFAIDTGSGRTL-SHRAEERFLMCSTFKGLLAAQILARVD +GGAERLDRLVHYTEKDLIFTSPVTKANVARGLSIDALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPESNRY--RGVLDTTTPKAIATTAQRLLLGDALSASSRA +QLERGMADCKPGLNRIRAVLPAGWRAADRPGTSVESETNDYALVRPPGRAPLLVAAYYDA +PGVSMEAREAVLRAAGTAFV--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus argenteus TaxID=985002 RepID=UPI000504B6E8 +---HSKELNNLEKKYNANIGVYALDTKSGKEV-KYNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIIKEIGGI +KTIKKRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000CD25FF5 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus auricularis TaxID=29379 RepID=A0A2T4M990_9STAP +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus kloosii TaxID=29384 RepID=A0A512QDF5_9STAP +--SHADELKNLEKKYNANVGVYALDTKSGKEI-KFNADKRFAYASTSKAVNSAMLLEQVP +--YDKLDKKVHINKSDIVDYSPVLEKYVGKDITVKELIKASMMYSDNTANNKIIDELGGY +KQIRKNLKELGDNTTQPSRYEPDLNNYSPKDKRDTSTPKAYGKTMKKLIEKDDLSKKNID +FLLDLMFNNKNGDTLIKDGVSKKYKVADKSGQATYASRNDIAYVYPKGQKPIVLVIFTNK +DDKNAKPNDKLISETAKKVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007CA23CA +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNTVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Frigoribacterium sp. JB110 TaxID=1434829 RepID=A0A1R4G5F2_9MICO +----DEELAPIEEEFHARVGVSVLDTGTGATI-DYRSEERFGFASTLKVFAVAEMLRQVA +--PEQRDELVTWTEETVADYSPITAEHVADGLTLAQLAEAALRDSDNAATNLILDRIGGV +EGMQAGLKRLGDSTTDVSDVEPELNEVVPGDTGNTTTPAAFTADLSALLRPEHLEPADRA +TLLEWMSGNATGDALIRAGAPADWAVADKSGGAG-AMRNDIAVVTAPGRDPIIVTILTEK +NDPDAAYEDEIVARVAEVVL--- +>[subseq from] Beta-lactamase class A n=1 Tax=Rathayibacter sp. PhB93 TaxID=2485103 RepID=A0A3N1NN57_9MICO +---VSAELAALEAEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKALAAAEFLRSVP +--ADERDEVVAWTAADVEAYSPVTSESIDGGLPLAQLAEAAVRRSDNTALNLVLDRLGGP +AALDRALEQLGDTTTDVVDEEPALNTIAPGSTANTTTPAAFTADLTAVALGEALPTADRA +LLLDWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDVAVVTPPGRDPIVLSVLTSR +NDPEAAYDDALVARAAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium carnosum TaxID=2023717 RepID=UPI00128E80B3 +--QITPELTNIEQHLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD +TKRVDLNQPIMINQSDILSYAPVTADRVGTSMTLAQLCNATMLTSDNTAANLVLNNIGGP +QSVTQFIGTLDDKTTRLDRIEPEVNNVSKAELRDTTTPIAMNSTLYNLLYGHTLSETARI +QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDNYGSRGITAAVWQQGKQPIMISIYLAQ +TGKPMADLNTTIAKIGQLIFTH- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007CA1614 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPFRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI00026BF0AE +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium cloacae TaxID=120107 RepID=A0A1E1EZH0_9SPHN +--------KEIEQETGGRLGVALVD-GSGALIlGFNRDERFAMCSTFKAPLAAAVLLGAE +SGKFGLEGQVPFTKDDILSHAPVVKQNLKRGLSMGELAEAAVEVSDNSAANLLLPMIGGP +EGLTAFFRAHGDSISRLDRREPDLNENAQGDPRDTTSPAAMAGLMARLLFKDM-KPESAE +KLRGWLNGSKTGDRRIKAGLPEGWTSGGKTGSCGT-AYNDVALVKSPSGAEYLLAVYLDR +PTVDERKAEAAIAETAASALD-- +>[subseq from] Beta-lactamase n=29 Tax=Bacteria TaxID=2 RepID=D2J684_STAAU +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RPQ8_9BACT +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=bacterium HR08 TaxID=2035403 RepID=A0A2H5VNZ0_9BACT +--RLEQEIARLARIAGGVVGVAARHLESGRRV-ALNGAERFPMASTYKVPIAVQVLTKVD +RGELALDQMITLEPADLSPGSGTLSDRVPGVLSVRNLLELMLLISDNTATDVLLRVAGGA +EAVTARLRELGIEEMRVDRPTKHVIARFDEDPRDTATPEAMVALLEQIYRGRALKRETTE +LLLDILRRCRTGEARLKGLLPPGTEVAHKTGTIG-GTTNDVGILTLPGDGHVAIAVFVKS +SDKDVPTRERAIAEIARAVHDFf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseolinea soli TaxID=2321403 RepID=A0A385SJC6_9BACT +--RLRDEIARITASVSADVGVAVLNMDTGDTL-TLHGRGHFPMQSVFKFPLAIMVLHEVD +KGTLALDQKIHLRKEDMLLWSPMAEKYPEGNLALSEILRYTVSQSDNSGCDVLFRLMGGP +KKVNDFLRGLGITQITIAATETEMHQAWPVQFTNWCEPVAMVALLKQFDRGNILSPTSRE +FLWKIMVETSTGPKRIKGLLPEGTVVAHKTGTGDYNAMNDAGIIVLPGGSHVAVVVYISQ +TKKDIPRLELVIAQISRVVYDQy +>[subseq from] Beta-lactamase class A n=1 Tax=Janibacter indicus TaxID=857417 RepID=A0A1W1YKW7_9MICO +---TSDPVAALEDKLDSRIGLYARNLGTDATL-AHRADDREAMCSTFKTLAAATALRRG- +---IDLDRVIRYATSDLVDYSPITGER--RRMTVGELCDAAIRYSDNAAANLLLERIGGP +RGLTREMRRLGDRVTRLDRWETELNTAIPGDPRDTSTPRALATTYRRLTLGDGLTGSDRW +ALRGWLEANTTSVKTFRAGLPQGWWSADKTGSGSYGVTNCAGLVSAPDGTQIVFAALTRR +STTDATGHPDLMRSIAELIVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Celeribacter ethanolicus TaxID=1758178 RepID=UPI000ADA5197 +--------QDRERELTARIGVCVRNLATGQVY-LHRAEERFAMCSTFKASLAALCLRESD +EGALDLGEALAFGAKDLLPTSPVTKAYVQAGLEIRSLCQAVVEWSDNTAANLLLARVGGP +ASVTRFFRDMGDPVSRLDRVEMDLNSNSPGDARDTTTPLAMAQNVQRMTMEGVLSERSRS +LLVDWMRNEQNAKNRIRAAVPRSWEVANKPGTTLNGAANDIAMLWAPEERAFAMAIYVDT +KKGNTPAAVSAIRGIAEVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Aquabacterium pictum TaxID=2315236 RepID=UPI001396C023 +---LARRLAGIERRSGGRLGVMVLPTGGSDRPwGWNADARFPLCSSFKLLLASMALHEVA +GGRLSLDERLPFTRANLIDWSPVTDSEADHGMTVGALCAATLATSDNTAANLVLARLGGP +AALTAYLRSLGDTVTRLDRNEPAMNRPGADPHWDTSSPRAMATTAQALMLGTGLPAPEQA +RLLRWMRASVTGGRRLRAGAASDWQVVTKTGTSNT-DSIDVGVLWPARRPPLVVAAFIRD +SQADGAVRDACLADVARLL---- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DA881C1 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKQSEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Oceanicola sp. D3 TaxID=2587163 RepID=A0A5B8BMU1_9RHOB +-------FELIEQEAQGSLGVLALDTATGRRA-GWRADERFPFNSTFKALLAGLVLERVD +AGAERLDRRIPIRAADILNYAPVTAAAQGNSLTIGQLCAAAVGRSDNTAANLLLDTLGGP +SGFTTRLAH---PDARIDAWEPALNTFAPGDPANTVTPSSMVSLMTGFLLEQRLSEASRA +QLLAWLRAASTGAKRIRAGVPSGWQVGHKTGTGPGGCCSDVAIIHPPQGAPLMLAIYVAG +SERPTARIEPLFAELTRIAC--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0005E5108F +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIILVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase class A n=1 Tax=Rathayibacter sp. PhB127 TaxID=2485176 RepID=A0A3N2FZW5_9MICO +---VSAELAALEAEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKALAAAEFLRSVP +--ADERDEVVTWTAADVEAYSPVTGESIDGGLPLAQLAEAAVRRSDNTALNLVLDRLGGP +VALDRALEQLGDTTTDVVDEEPALNTIAPGSTANTTTPAAFTADLTAVALGEALPAADRA +LLLDWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDVAVVTPPGRDPIVLSVLTSR +DDPEADYDDALVARAAAVVL--- +>[subseq from] BETA-LACTAMASE n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000068334F +-----KELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium sp. CAP-1 TaxID=2676077 RepID=UPI0012BB1F70 +--------KEIEQETGGRLGVALVDSKGALLL-GFNRDERFAMCSTFKAPLAAAVLIGAE +TGKFGLDGQLSFTGDDILDYAPVVKKNRKRGMSMSELAQAAVEVSDNSAANLLLPMLGGP +DGLTAFMRAHGDSVSRLDRNEPDLNENAPDDPRDTTSPAAMAGLMGRLFFRD-LQPGSAE +KLRTWFNASSTGDHRIKAGLPAGWTSGSKTGSCGT-AYNDVALVKSPAGDDYILAIYLDR +PTVDAKKAEAAIAETAQAAL--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A2L1J110_PSEAI +-----------------------------SQI-LYRADERFAMCSTSKVMAAAAVLKKSE +GEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTND-------------------- +----------------------- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0002BB2E43 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus sp. HMSC58B01 TaxID=1795299 RepID=UPI0008A58BE4 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISEAAKNVINKf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis sp. KK2 TaxID=1855727 RepID=UPI00097E5710 +-----DNIRDIEKRSGGRLGIAVVK-DDGQLLfGSNANDRFAMCSTFKLLLAGQVLRGAT +DGGPSLRTPLPLTKADIVPHSPYSEANLALGLRLGLAAEQIVTVSDNAAANLILKATGGP +EAFTRRMRDMGDAVTRLDRYEIELNENAVGDPRDTTTPQAMAKSAARLVYGDHLDPSYRK +SLREWMVASKTGLARIRAGLPAGWLSGDKTGSCGN-AYNDVAFVEAPDGGKYVIAVYLDR +PVVEGEAANAVIADVTRAVVE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Gordonia sp. TaxID=84139 RepID=A0A3S0U7Q1_9ACTN +---ATAGLRELEVANRARIGVYARDLRSGKTV-VHRPDDSFAICSTFKAYLVARVQQLVE +RDELSLATRVYVDPGEIKTHSPVTQRYAGGPVDIGVLCRAAVQESDNTAANLLLRAIGGP +PGLTAFARSIGDERTRLDRWETELNSAIPGDPRDTSTPGALAGGFTAILAGDVLAVSRRQ +QLTDWMLANQT--SSMRAGLPAGWTSADKTGGGDYGSTNDVGLVMGPDGQRVMVAVMIRS +TGPEVPGYRPLVGEVTRAVL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DE44984 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3S4HMN4_KLEPN +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPA-------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. M26 TaxID=1762962 RepID=UPI00073F7FB7 +---LDERIGLLEKRHNAFVGVYGQNLDADHTV-AHRDNDMFAMCSTFKAYLSARVLQKAQ +RGELRMTDTRMVDPTAVLPNSPITGPKAGGALSLADLCQAALQRSDNTAANMLLAVIGGP +PAITEFARSIGDDRTRLDRWETELNSALPGDPRDTSTPRSLGGGFRAMLTGDVLDEAHRR +QLEDWMRGNVT--SSMRAGLQPGWTTADKTGSGDFASTNDIGIVFGPNGERILLAIMTRT +QSADAESLRPLIGEVTTLVL--- +>[subseq from] ARL family class A beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=UPI000D1BACEE +----AQGLTKLEHKNDATVGVYGINTATGQTY-SHNADTRFAYASTFKAITSGLLLQQNS +--PEALNKTVTIKESDIVAYSPVTERYVGKTMTLRQLISAAMLQSDNTASNIIMEQLGGL +DQISSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHSLQQLLTTDAVAPQQRK +FLQNLMFNNETGDSLIKKGVPDSYKVGDKSGQGTYGTRNDVALIYPKHQKPIVLVVFTKH +QQQDAQPQDELVAQAARHAIH-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus argenteus TaxID=985002 RepID=UPI000B590722 +----AKGLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase OXY-1 n=2 Tax=Burkholderia gladioli TaxID=28095 RepID=A0A095F0N6_BURGA +---ADSPFSDIERRNGGRLGVFAIDTGSGRTL-SHRAEERFLMCSTFKGLLAAQIMARVD +SGAERLDRLVHYTEKDLIFTSPVTKANVARGLSIDALCQATLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPESNRY--RGVLDTTSPKAIATTAQHLLLGDALSASSRA +KLERAMTDCKPGLNRIRAVLPAGWQAADRPGTSVERETNDYALVRPPGRAPLLFAVYYDA +PGVSMEVREAVLREAGTAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus simulans TaxID=1286 RepID=A0A2X3QUF0_STASI +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVS +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044F2F88 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A291N1A3_SPHYA +--------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ +GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAEAAVEVSDNSAANLLLPMLGGP +EGLTSFIRAHGDKITRLDRIEPELNENIAGDPRDTTSPAAMAGLMGRLLFRDM-AAADAD +RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR +PTVDDKKAEAAIAEAAHSAL--- +>[subseq from] UPI00143F05F1 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00143F05F1 +----AKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. IBVSS1 TaxID=1985171 RepID=UPI000A2E859A +---LRRAIATIEHDAGGPIGVALLDTHTGARF-NHRASSRFPLCSTFKLLLAARLLHGAE +TGLWQLGERLPIRREDMLNNAPFSETRIGGSASLLEMAEAMCVLSDNPAANLALARQGGP +AALTAWLRSIGDTTTRLDRNEPEMNNETPGDPRDTTTPTAMLATSRALVEGRILSAAGRA +RLLGWMQASRTADTMIRAALPPGWAEANKTGAGSWRARNIVSRITPPGRRPIWVAAYLFA +AKSELAERNRHFVPLGRAIVE-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00124E4FFB +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=UPI00069FA75C +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Aquabacterium pictum TaxID=2315236 RepID=A0A480AX23_9BURK +---LARRLAGIERRSGGRLGVMVLPTGGSDRPwGWNADARFPLCSSFKLLLASMALHEVA +GGRLSLDERLPFTRANLIDWSPVTDSEADHGMTVGALCAATLATSDNTAANLVLARLGGP +AALTAYLRSLGDTVTRLDRNEPAMNRPGADPHWDTSSPRAMATTAQALMLGTGLPAPEQA +RLLRWMRASVTGGRRLRAGAASDWQVVTKTGTSNT-DSIDVGVLWPARRPPLVVAAFIRD +SQADGAVRDACLADVARLL---- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura rudentiformis TaxID=359158 RepID=UPI00124D11AC +--NVTKELRKLETDYKGRIGAFAIDTGTGKTV-SYRANERFPADSTFKAPLCGAILQKAR +TDPGLLNRILKWTKEDVVPNSPITTWSPVGGLTVSQLCQATVTTSDNTAANLLLKQIGGP +AGMTRYYRSLGDKVGRMDRYEPEHSYWKVGDVQGTITPATMASNLQKMTLGSALAPQDRQ +QLLAWMRGNYTGNMHIRAGLPNNWLIGDKTGHGSYGTGGDIAVVQPPSGAPLILAIYSHR +NAEDGVSDPKIFGATASVL---- +>[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. DHF22 TaxID=2571748 RepID=UPI001316B713 +--TAHDALAAIERRHGGRLGVFALDTGTGRTL-AHRADERFLMCSTFKGLLAAQVLARVD +AGHDVPGDLVHYTASDLIFTSPVTKANLAHGMTVGALCRAILEESDNTAAILLMKRAGGP +AALTQFLRDLGDTVTRSDRYELASNDY--DGELDTTTPRAIATTARTILLGNVLSAASRA +QLEAGMVACKPGRNRLRAALPTGWHAGDRPGTSVARESNDYALVRPPGRAPLLVAAYYDA +PGTSMDAREAVLREAGGVF---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A346QRV8_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDATMPAAVATTLRTLLTGEVLTLASRP +QLIDWMGADKVAGPLLLSALPAGGCIADGSGPGER------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Ruania albidiflava TaxID=366586 RepID=UPI0009FEE7D9 +----ETELQNLEERTGRTIGLYATNLSTGREV-AYRHTEPFPMCSLFKVLAVAGLLTEHS +PYGDYWEEKIPFGPEDIVENSPITSAHQEREMTVSELADAALRFSDNTAGNLLLEELGGP +AAVTRFARRFQATATRLDRWEPELNEAEPGDLRDTTTPADIARLYQAFLVEGRLGQLGQT +RLRDWMLRNTTADERLRAALDGEYELADKTGAGEFGVVNDAGIVWRPDGSVTVISVLTRS +DSRSADNDNTVLVAAARAAL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0001BE5B83 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKPLIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000446268E +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPDAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RND1_9BACT +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETSKSVMKEf +>[subseq from] ARL family class A beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=UPI00143831CE +----AQGLTKLEHKNDATVGVYGINTATGQTY-SHNADTRFAYASTFKAITSGLLLQQNS +--PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNIIMEQLGGL +DQLSSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHNLQNLLTTDAVAPQQRK +FLQNLMLNNKTGESLIKKGVPNSYKVGDKSGQGTYGTRNDVALIYPKHQKPIVLVVFTKH +QQQDAQPQDELVAQAARHAIH-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DE28C69 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMKYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Sandarakinorhabdus cyanobacteriorum TaxID=1981098 RepID=A0A255YG74_9SPHN +---LRRAIAAIEHAAGGPIGVSLIDTHTGARF-SHRANDRFPLCSTFKLLLAARLLHGAE +TSLWQLGERLPIRREDMLNNAPFSETRIGGSASLLEMAEAMCVLSDNPAANLALARQGGP +AALTAWLRSIGDTTTRLDRMEPEMNNETPGDPRDTTTPTAMLATSRALVEGRILSPAARA +RLFGWMQASRTADTMIRAALPPGWAEANKTGAGSWRARNIVSHITPPGRRPIWVAAYLFA +ARSELAERNRHFVPLGRAIVE-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00129124C0 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Uncharacterized protein n=1 Tax=Frigoribacterium sp. RIT-PI-h TaxID=1690245 RepID=A0A0N0L0B9_9MICO +--EVESALADLETRYDARVGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAAPLDATD +--DADLDRVVTWTQAEVDAYSPLTGQHVADGLPLRQLAEAAVRQSDNTALNLVLTELGGP +TGLDAALAAQGDDVTDVVHGEPELNTLTPDSTADTTTPAAFTATLARISDGDWLAADDRA +TLLEWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVVPPSGDPVVISVLTTR +NDPAATYDDALVAEAARIAL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012EE9BEA +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIITEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLNKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Komagataeibacter hansenii TaxID=436 RepID=UPI00094F5CFB +-------LSGYERATGGHVGVYAHNIVTGRKL-LWRADERFVMCSTFKASLVACVLSHVD +QGRDGLDRVIPLTGADIQDYAPVAKAALAQGMSVEDMCKGAVEQSDNSCATLLLSRIGGP +PALTAFWRAMGDGTTRLDDPEPFLNRTPAGGVRDTTTPAAMAGIMQGLVLGAVLSPSSRA +LLTRWLIGCQTGKNRLRAGLPANWVVGDKTGNNARDAAGDIAVAWPHPDMPIVMCVYTRG +GTPTEPRFANVFAGVGRLVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. Root1279 TaxID=1736443 RepID=A0A0Q7EDD6_9CAUL +-------LSALEARHGGRIGFAARDLATGREL-RWRGEERFVYCSTFKMFLAAATLLRVQ +SGEERLDRAIPITRADMINHAPVTEPAVGGTLTIQDLMKGTVEVSDNPAANILIRELGGL +DVLRDFYRGIGDQTTTVDRLEPEMNRL--DGDKDTIQPVQAVANLYRLLVETPLSAESKA +LLLRWMTDTPTGVGRIKAGVPAGWTVAHKTGTGGYGPTNDIGVLYPPSGEPVIMAVYNHA +TRSDEAQREATIAEAARLAL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000AD86F67 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A2W4TK90_9PROT +------DLAALEARHGGRLGFAVRDTATGQAL-VWRGDDRFVYCSTFKMYLAAATLMRVQ +EGQERLDRAIPVTAADMINHAPVTGAAVGGTMTIEALMKGTVEVSDNPAANILIRELGGL +AEMQAFYRSLGDMRTRVDRLEPEMNRL--DGDKDTITPAQSALNIETLFVNSPLVQSSRQ +RLLGWMLASPTGPERIKAGVPAGWRVAHKTGTGGYGPTNDIGLIYPPSAPPVVVAAYFHA +TESTEAQRDAVIADATRMAL--- +>[subseq from] Beta-lactamase n=1 Tax=Komagataeibacter hansenii TaxID=436 RepID=A0A318PZ94_KOMHA +-------LSGYERATGGHVGVYAHNIVTGRKL-LWRADERFVMCSTFKASLVACVLSHVD +QGRDGLDRVIPLTGADIQDYAPVAKAALAQGMSVEDMCKGAVEQSDNSCATLLLSRIGGP +PALTAFWRAMGDGTTRLDDPEPFLNRTPAGGVRDTTTPAAMAGIMQGLVLGAVLSPSSRA +LLTRWLIGCQTGKNRLRAGLPANWVVGDKTGNNARDAAGDIAVAWPHPDMPIVMCVYTRG +GTPTEPQFANVFAGVGRFVAR-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DE4EFC9 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0004466297 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNNANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Microbacterium sp. JB110 TaxID=2024477 RepID=A0A368LDL2_9MICO +----DEELAPIEEEFHARVGVSVLDTGTGATI-DYRSEERFGFASTLKVFAVAEMLRQVA +--PEQRDELVTWTEETVADYSPITAEHVADGLTLAQLAEAALRDSDNAATNLILDRIGGV +EGMQAGLKRLGDSTTDVSDVEPELNEVVPGDTGNTTTPAAFTADLSALLRPEHLEPADRA +TLLEWMSGNATGDALIRAGAPADWAVADKSGGAG-AMRNDIAVVTAPGRDPIIVTILTEK +NDPDAAYEDEIVARVAEVVL--- +>[subseq from] BETA-LACTAMASE n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0000110964 +------ELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKNTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000B170FB9 +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Phormidium ambiguum IAM M-71 TaxID=454136 RepID=A0A1U7I927_9CYAN +-nELRNQIEQISHTAQGQVGVTATVLETGETV-TLNGDRQFPMQSVYKFPIGMAVLAQVD +RGKLSLDRRVRVKASDFVSHSPIRDKYPQGVLSLAELLKYMVSESDGTACDVLLELVGGA +EVVTQYLRNLGVNGIVVANTEKEIGQDKAVQYRNYATPDAAVALLRALYEGKGLSKSSQA +LLLRLMTETPTGLRRIKGLLPDGTVVAHKTGTSRTAATNDVGLVTLRNGQHLAIAVFVSD +SKANDTIREQVIAKVARAAWDKw +>[subseq from] class A beta-lactamase n=1 Tax=Microlunatus speluncae TaxID=2594267 RepID=UPI0012662C96 +--AATDKITELERRHDITIGLYARNLETGATL-GHRTEERFPHCSVFKALAVATLLDDRR +HQRGILERGVHYAPKSLVDYSPFMQECLDRGPTGADVCKATLQLSDNGAGNWVLSVIDGP +AGATRFVRRLGDRVTRMDRWETELNSAVPGDPRDTSSPRAIADTFTRLIIGNALRPAERR +RLTTWMLGNQTSDDRFRAGLPEGWRLADKTGGGAYGVSNDVGIAWTDRNVPVVIAAFTRS +DREDAPTTDAVVAELARIS---- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WUY8_9BACT +-nELRDRIEQISQAARGRVGVTATVLETGESV-TLNGDRQFPMQSVYKFPIAMAVLAQVD +QGKLKLDRKIRVETSDVLQGSRILDEKSQGMFSLAELLKYMVSESDGTSCNVLLRQVGDP +RIVTEYLRSLGINDIVVANTEKELAQDPAVKYRNYATPDATVVLLRAFHEGKGLSKSSQA +LLLQLMTETTTGPQRIKGLLPDGTVVAHKTGTSSTAATNDVGLVTLPNGRHMAIAVFVSD +SGANNATREEVIAKVTKAAWDEw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WVB1_9BACT +--TLQKRIEEIAAGAQGKVGVAAVVLETGEAF-GFNENEHFPMQSVYKFPIAMAVLKQIE +QGNLKLEQNIRIEKSDLVPRSPIRDRFPQGTMTLNDILKYSVSDSDGTACDVLLKTIGGA +DAVTKYLRDTGVKDIVVATTERAMSQDESVQYQNWASPQATNDLLRLLHSGGVLAESNRA +LLLQWMTETPTSAKRIKGLLPAGTVVAHKTGTSNTRATNDVGLVTLPDGKHLAISVFVSD +SKADETTREEVIAKITRAIWDEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus capitis TaxID=29388 RepID=UPI00019291AB +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. PhB152 TaxID=2485190 RepID=UPI000F4B0E60 +---VSAELAALEAEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKAPAAAEFLRSVP +--ADERDEVVTWTAADVEAYSPVTGESIDGGLPLAQLAEAAVRRSDNTALNLVLDRLGGP +IALDRALEQLGDTTTDVVDDEPALNTIAPGSTANTTTPAAFTADLTAVALGEALPAADRA +LLLDWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDVAVVTPPGRDPIVLSVLTSR +NDPEAGYDDALVARAAAVVL--- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium bisphenolivorans TaxID=1335760 RepID=UPI0003A110CF +--------KQIEAETGGRLGVALVDSRGALIL-GFNRDERFAMCSTFKAPLAAAVLTGAE +GGKFGLEGEISFGKADILEHAPAVKKNLKRGMSMDELAAAAVELSDNSAANLLLPMIGGP +EGLTRYIRAHGDTVTRLDRTEPSLNENAAGDERDTTSPAAMAGLMARLIFRD-LKPDSAA +KLRGWLNASSTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR +PRVDSKAAEAAIAETASAALD-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Bacillales TaxID=1385 RepID=UPI00046F34FA +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DA73BFD +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKELGDKGTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Novosphingopyxis baekryungensis TaxID=279369 RepID=UPI0003B49E15 +--DLGAQMVAIETETGGRLGAFVVDADGKSLL-AYRADERFAMCSTFKTLLAAMVLEGVQ +QGSYDLDQPLAFDPADLVGYSPYVERYAAVGVTLGGAAGAAVSLSDNSAANLLYDLVGGP +GTLFQWLRTTGDKVSWPSRLEPDLNENAAGDMRDTTTPAAMGKTLHRLLTGNRLNNISKA +QLETWLRASETGGARIRAGLPARWVVGDKTGTCGNPAYNDVAVVRPSPREPYVIAVYLDR +PATDAAAADAAIAKVAALAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Flavobacterium sp. BBQ-18 TaxID=1932779 RepID=UPI0013771F62 +-------LSDLEARNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKMYLAAATLLRAQ +AGQERLDRRIPITTADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP +SAMQTFYRGIGDDSTRSDRFEPEMNRL--DGDKDTILPNQSVANLRRLFLNSALTAASRA +LLLQWMTDTPTGQNRLRAGTPAEWRVAHKTGTGGYGPTNDIGLLYPPDGQPVIVAAYYHA +TRATDDANAAVIAEATRRAL--- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinomadura mexicana TaxID=134959 RepID=A0A238UT07_9ACTN +--DLNTTLQELEKSYDGRIGAVGIDLGTGRTV-GYRADERFPFDSMFKVFACAAVMQKAR +TGEPLMDKVLHWKPADMAENSPETTEYTDTGMTPAQLCRAGVTKSDGFAGNTLLGQLGGP +RGLTRFLRATGDGTSRLDRPEPHLTEWKPGEDRDTTTPAAAARTFTKLTTGKTLHARDRA +RLLGWLKGSLTGANRIRAGLPKDWTVGDKTGTGGYGTANDIAIVWTPGSAPLVLSVFTNR +NR-QVPHDDKVIASTATALAK-- +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium faniae TaxID=570446 RepID=A0A1G4QWY0_9SPHN +--------KEIEEETGGRLGVALVDSSGALIL-GFNRDERFAMCSTFKAPLAAAVLLGAE +SGKFGLEGQVPFTKDDILPHAPVVKQNLKRGLSMAELAEAAVEVSDNSAANLLLPMIGGP +EGLTAFFRAHGDSFSRLDRKEPDLNENEEGDPRDTTSPAAMAELMTRLIFKDM-PPESAE +KLRGWLNGSKTGERRIKAGLPTGWTSGGKTGSCGT-AYNDVALVKSPSGAEYLLAVYLDR +PTVDEAKAEAAIAETAASALD-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. YR708 TaxID=2135746 RepID=A0A4R2VAB7_9MYCO +-----TRIAALEKRHNAFVGLYGQNLDSKVEV-AHRDGDLFAMCSTFKAYLSARVLQKAQ +AGELRLTDTVVVDPELLRANSPRTEPNVGKPMALSDLCAAALQVSDNTAANLLLRVIGGP +PAITAFARSIGDDRTRLDRWETELNSALPGDPRDTSTPRALGGGVLAVLAGTVLDEPHRR +QLEDWMRANTT--SSMRAGLPPGWTTADKTGSGDFASTNDVGIAFGPRGERLLLAIMTRT +QTANTPALRDLVGEVATVA---- +>[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. YR782 TaxID=2135747 RepID=UPI000D362531 +-----TRIAALEKRHNAFVGLYGQNLDSKVEV-AHRDGDLFAMCSTFKAYLSARVLQKAQ +AGELRLTDTVVVDPELLRANSPRTEPNVGKPMALSDLCAAALQVSDNTAANLLLRVIGGP +PAITAFARSIGDDRTRLDRWETELNSALPGDPRDTSTPRALGGGILAVLAGTVLDEPHRR +QLEDWMRANTT--SSMRAGLPPGWTTADKTGSGDFASTNDVGIAFGPRGERLLLAIMTRT +QTANTPALRDLVGEVATVA---- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0002B95516 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chitinophaga sp. ysch24 TaxID=2683588 RepID=UPI0012F8558F +--AIRQKIGPITSTAQGHVGVALKLLETGDTL-SFGGNDRYPMQSVFKVPLAIAILDQVD +KGRLSLSQKITIRKEELRPWSPIRKKYPEGTMSLSDVLAYTVSQSDNNGCDILFRLLGGT +AYVNKYIHSLGIDSINIVATEEDMSKAWEVQYTDWSTPLAIVQLMEGIHKGSWLSKSSND +FLLKIMTETNTGPGRIKGLLPANAVVAHKTGTSDTAATNDAGIITLPGGKHLAIVVFVSD +ARAAEKTRDEVIAKIARLCWD-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000B959D90 +---HAKELNNLEKKYNAHIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. KM4 TaxID=1628191 RepID=A0A0F3LFS6_9CAUL +-------LSDLETRNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRRIPITTADMINHAPVTEPAVGASLTVEQLLKGAVEVSDNPAANLLLKAMGGP +SAMQTFYRGIGDDSTRSDRFEPEMNRL--DGDKDTILPNQSVANLRRLFLNSALTAASRA +LLLQWMTDTPTGQNRLRAGTPAEWRVAHKTGTGGYGPTNDIGLLYPPNGQPVIVAAYYHA +TGTSDDANAAVIAEATRRAL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000E3D740C +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDNIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas sp. B6 TaxID=1295626 RepID=UPI001237643A +-----------------RLGVHALDTVTGATA-SHRADERFAFCSTVKPLAAAAVLAAR- +-GVDGMDERVPVEAADLVTYSPVTEQRVGVGMTWRELVDAALRFSDNTAGNLLLAGAGGP +AALTAWLRGLGDDVTRSDRTEPDLNAFVPGDERDTSTPGALAGTYRTLVLGDALGGPERD +LLTDAMLRSTTGDALVRAAARPGWEVADKSGAGAYATRNDVAVVWTGAGAPVVLAVLSDR +ADPGAERTDAPVAEAARVVLD-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0006B4CE25 +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDAAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura flavalba TaxID=1120938 RepID=UPI0003A4B65D +---LDRALRALEKSYDGRIGAVGIDLGTGRTV-GYRADERFPFNSVFKAFACAAVLHKAR +NGSPLMDRIVRWTPSEVAENSPETTEYTDTGMTPAQFCRAGITRSDGFAGNMMLRQIGGP +AGLTAFFRAQGDRTSRLDRPEPGLTEWSPGERRDTTSPAAAARTFSALTAGGALHPDDRA +RLVGWLKATVTGDKRIRAGLPKTWTVGDKTGTGGHGTANDLAIVWPPGAAPIILSIFTNR +TADNTPAEEKVIASTATALA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Lactobacillus gasseri 224-1 TaxID=679196 RepID=D1YJY8_LACGS +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSA----------------------------------------- +----------------------- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000A60EF7A +---HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKNGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. Leaf363 TaxID=1736353 RepID=A0A0Q5V1Y8_9CAUL +------DLSGLERADGGRIGSAAHNTATGERL-HWRGDERFVYCSTFKMYLAAATLMRVQ +AGEERLDRRIPITRADMINHAPVTQPAVGAGLTVEQLMKGTVEVSDNPAANLLLKAMGGL +ETMQAFYRGLGDPSTRVDRFEPEMNRL--DGNKDTITPSQSVANMQRLFIDPALSAASKA +MLLGWMTTSPTGTDRLKGGVPAGWRVAHKTGTGGYGPTNDIGVLYPPSGAPVIVAAYYHA +TRDTDARNAAVIAAATRLALASf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000345FA42 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI001232D366 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGP---------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Euryhalocaulis caribicus TaxID=1161401 RepID=UPI0003A63303 +--SLEHHLARIAGNLDGVVGVSIRDLSSGAAF-GLNADEAFPMASTFKIAVAGAILEQVD +SGELTLEQMVTVDPDMHVPSEIIADRFIHPGLSVANLMELMLTQSDNTATDVLTELAGGP +AAVTGWLASIGVEGQRVDRDTAGLLRAFYNDPKDTSTPDAMADLLTRIVQGEALGADSTE +FLVGVMERCRTGEGRLKGLLPEGVTVAHKTGTVG-GTVNDVGVMTLPGGRQVVIAVFVKA +SPAPAEARERTIAEIARTAYDYf +>[subseq from] Beta-lactamase class A n=2 Tax=Insolitispirillum peregrinum TaxID=80876 RepID=A0A1N7JH88_9PROT +---MEARLKKLEAQSGGRLGVAVLDSATGQVT-GNHLDERVAMCSTVKTLIVAYVLARVD +RQMETLDRRIVFTAHDLVSPYKATQPHVGPEMSIAALCEAAITVSDSTAANLLLTSFGGP +VALTSYLQSLGDEVTRSDRFELALNVVKPGEAHDTTTPRAMVGTLHRLLLDDALLETSRA +RLTNWMIEAKDATRRLRVGLPAGWRIANKPGTWEGISTNDVAVIWPPSRAPIVVATYLGN +APGSIIMQEGILADVARIIAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Kocuria halotolerans TaxID=405770 RepID=UPI00101E213F +------GLESLEAEFDARIGVSALDTGSGDVV-EHRADERFGYASSLKVLAAAELLQQVP +--ADQREERVTWTQEDVDAHSPVTSEHLDEGLTYPELAEAAVRQSDNTAMNLMLARIGGP +AGLDAALEELGDTTTEVVNEEPALNAVEPGGTDDTTSPSAFTADLDALFDPQVLDPADRE +TLIDWMSGNPTGDTLIRAGAPEDWAVAEKSGGAG-GIRNDVAIVTPPDRAPIVITVLTQR +NDPEAEYDDALVARAAEAVLGEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00066C2243 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=20 Tax=Staphylococcaceae TaxID=90964 RepID=A0A3S7GZ77_STAHO +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00066C5811 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI001067BE7A +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00138E205F +---HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Alishewanella jeotgali KCTC 22429 TaxID=1129374 RepID=H3ZHA0_9ALTE +---AAQRLQALEVG-HARLGVCLLDTATGEVS-GNRMDEYFAMCSTFKLALAAAYLREAD +QGRLDLDEMLPYSEADLLPWAPVTREHLAKGMTIIALLQAAQQFSDGVAANLMVKRLGGP +AMVTAKFREMGDNITRLDRYEPDLGLVLSADLRDTTTPRAMAQLVQRITCGELLQQDSRQ +RLLQWMESTNTGSKRLRAGLPATWRSGNKTGTGRTNKYNDIAITFPPGRSPIIIAAYFDS +GEQIEDRHQAVLADVGRIAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNT360 TaxID=1288080 RepID=UPI00041A2931 +-----AAFARLERIHYAHLGLYAVDTGNGNQV-TWNDTRRFSYNSTVKSFLAAAVLKKNR +-SDGDMDRVLHYDRSDLTANSPVSEKHVGTGMSRRALCDAAVRYSDNTAANVLFEDIGGP +GRLGTFLKTLHDTVTRTDRVEPHLSRWSPGEQHDTSTARQMASDLRELVLGRTLRTAERR +QLTTWLRTNTTGDTTIRAGVPKGWKVGDKTGTGSYAARDDIAVIWPPGRKPLVMAVLTYR +DGKNAEADDKLPADAAKAAIT-- +>[subseq from] Beta-lactamase n=1 Tax=Alishewanella sp. HH-ZS TaxID=1856684 RepID=A0A1C2BTT4_9ALTE +----AKRLQALEVG-HARLGVCLLDTATGEVS-GNRLDEYFAMCSTFKLALAAAYLREAD +QGRLDLDEMLPYSEADLLPWAPVTREHLAKGMTIIALLQAAQQFSDGVAANLLVKRLGGP +AMVTAKFREMGDNITRLDRYEPDLGLVLSADLRDTTTPRAMAQLVQRITCGELLQQDSRQ +RLLQWMESTNTGSKRLRAGLPATWRSGNKTGTGRTNKYNDIAITFPPGRSPIIIAAYFDS +GEQIEDRHQAVLADVGRIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium flaccumfaciens TaxID=2035 RepID=A0A4R6DHB4_9MICO +---IDRALAALETEYDATVGVVATDTATGESV-AYNGDRRFGYASTIKAFAAAQFLRSVQ +--GSDRDEVVHWTAADVAAHSPVTEQRVADGLSYAALAEAAVRQSDNTALNLVLTRIGGP +NALDSALHDLGDDVTQVVHDEPDLNTIEPGSTEDTTTPAALAADLATLFDGTTLDAADRA +QLLDWMGGNATGDTLVRAGAPTGWTVADKSGGAG-GIRNDIALVTRPGGAPIVIAVLTAK +NDPAAAYDDTLVAKTASTVLGAf +>[subseq from] Beta-lactamase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A2H1KY28_9MICO +--EVDSAIADIEKKYDARVGVHAMDTSDGSTI-EHRSKERFGFASTIKSFAVAELLARTT +--PAELDEHVTWTKEDVEKYAPVTEKHLGDGLPLEKVAEAAIRVSDNAAANIVFDHIDGP +KGLDSALEDLGDSTTEVIDREPDLNTIDPGSADNTTTPAAFSNDLAALLEPEHLSDEDRT +VLIDWMSDNETGDPLIRAGAPAGWKVADKSGHAD-ALRNDVAVVFPPKRDPIVIAIMTEN +NDPNTESDAALIEDIAHAVLGAf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012EE3504 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVKYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Rhizomicrobium sp. SCGC AG-212-E05 TaxID=1799655 RepID=A0A177Q804_9PROT +------AIAAIERKHGGRLGVFALDTATRKTM-SWRADERFTMCSTFKLLLAAQVLAKVD +AGTENPNRKLFYGPGDLIFGSPVTTRHVDERLSIAVLTRAIVETSDNTAAILLMRAMGGP +ESLTRFVRSLDDEATRMDRYEPDANLY--DPLLDTTTPRAIILTLRRILMGKVLSPRSGQ +LLEGWMIASTTGTERLRAAFPRRWIAGDKTGTSAERQTNDIAFLRPPGRRPLLIAAYYDA +PRVSLAEREQVMRETGEAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis subsp. tessellarius TaxID=31965 RepID=A0A225C7W9_9MICO +--AADAAFAALEERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMERAVPIEAADVLAYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLMFRALGGP +SELDAALTALGDDTTVVARDEPTLNEATPGDDRDTTTPRATAALLRAYALGDALDDDERA +LFTGWLKATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDAAP--IAAHSSK +DRQDAVADDALISGAAKAAAQ-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI0002506AF6 +---HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00066A6F10 +---HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. Ae356_Ps1 TaxID=1885032 RepID=A0A1Q8JTS2_9PSEU +--------DGVEREFGRRIGVHVLDTGTGTTA-GHRDGERFLMCSVVKALMAGFVLHRSV +ADPALLDRPVRWGRADLLEYAPVTFRHVDSGLSVAQLCEAAVTVSDNTAHNLLLREVGSP +ADLTAWLRSTGDGVTRADRYETALNDV--DGDRDTSTPAALAATLRALTTGDVLPSAQRD +RLVGWLRANTTGDEQIRAGVPDGWQVGDKTGSGPLGEKNDAGVLFPPQGAPVLLTVFTVP +ADPDDDRGAAAVASATRAA---- +>[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium naphthalenivorans TaxID=273168 RepID=UPI0008328B6C +----TDALRAIERDAGGRLGVFVHDTASGRSF-GWRQNERFTHCSSFKLSLAAMMFAGRD +AGTIDLGRVLHWTQADLLPHSPTTTPHVGSGLTVNELARAALIESDNTAANVLLKTFGGP +EAVTRFWRTLGDRVSRLDRFEPDLNITPPGTELDTTTPKAMAGTLQTLLTGQHLSVQSRE +TLKTWMSAVTTGSDRLRAGFPKSWASGDKTGTGRY-TYVDLAFGGPAGKPPLYVAAYFEP +AVHRDPAATAVLAAVGDVAARHy +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00124E5FF9 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI000807659E +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKNDKPNDKLISETAKNVINKf +>[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium sarraceniae TaxID=1534348 RepID=UPI00138BFA96 +-----TRIEALEKRHNAFVGLYGQNLDSKVEV-AHRDGDLFAMCSTFKGYLSARVLQKAQ +AGELRLTDTVLVDTELLRPNSPRTEPNVGKPMALSELCAAALQVSDNTAANLLLRVIGGP +PAITTFARSIGDDRTRLDRWETELNSALPGDPRDTSTPRALGGGILTVLTGDVLDPPHRK +QLEDWMRANTT--SSMRAGLPPGWTTADKTGSGDFASTNDVGIAFGPGGERLLLAIMTRT +QSANTPALRDLVGEVATVAV--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00076973AD +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=7 Tax=Staphylococcus TaxID=1279 RepID=A0A4Q9WNF3_STAHO +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044A9D50 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012AFAFAA +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIETSMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Paenibacillus polymyxa TaxID=1406 RepID=UPI000578158D +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A177K1A4_SPHYA +--------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ +GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAEAAVEVSDNSAANLLLPMLGGP +EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDM-QAADAD +RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR +PTVDDKKAEAAIAEAAHSAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007696180 +----AKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. IP1 TaxID=2021637 RepID=A0A2G1LIY6_9SPHN +--------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ +GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP +EGLTSFIRAHGDKITRLDRIEPELNENIAGDPRDTTSPAAMAGLMGRLLFRDM-AAADAD +RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR +PTVDDKKAEAAIAEAAHSAL--- +>[subseq from] Beta-lactamase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8SFD4_9BACT +--DLRGQIEQIAREAKGRVGAAVLIVETGETV-AVHGDEQFPMQSVYKLPIGMATLREVE +RGRLKLEQQVRVEKSDLVSHSPIRDKYPQGGLTVRECLRAMLVESDGTASDILLRLAGGP +RRVTDYLRGLGVTEIVVATSEQEMAQGEMVQYQNWATPEAMAGLLRALQQGRGLAAGSRA +LLLQFMTETTTFPHRLKGRLPAGTVVAHKTGSSGTAATNDVGVITLPNGRHLLVVVFVSD +STADDATRDDVIAKIARAAYD-- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A2A3YQ02_9MICO +--EVDSAIADIEKKYDARVGVHAMDTSDGSTI-EHRSKERFGFASTIKSFAVAELLARTT +--PAELDEHVTWTKEDVEKYAPVTEKHLGDGLPLEKVAEAAIRVSDNAAANIVFDHIDGP +KGLDSALEDLGDSTTEVIDREPDLNTIDPGSADNTTTPAAFSNDLAALLEPEHLSDEDRT +VLIDWMSDNETGDPLIRAGAPAGWTVADKSGHAD-ALRNDVAVVFPPKRDPIVIAIMTEN +NDPNTESDAALIEDIAHAVLGAf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0009168039 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELEDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A430BHK4_SPHYA +--------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ +GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAEAAVEVSDNSAANLLLPMLGGP +EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDMASA-DAD +RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR +PTVDDKKAQAAIAEAAHSAL--- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. Leaf168 TaxID=1736283 RepID=A0A0Q5MWH3_9CAUL +-------LADLEARNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKLYLAAATLLRVQ +AGQERLDRRIPIAAADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP +SAMQTFYRGIGDDSTRSDRFEPEMNRL--DGDKDTILPNQSVANLERLFLDPTLTAASRA +LLLQWMTDTPTGQNRLRAGTPADWRVAHKTGTGGYGPTNDIGLLYPPNGQPVIVAAYYHA +ARATDDANAAVIAEATRRALK-- +>[subseq from] Beta-lactamase n=1 Tax=Vibrio caribbeanicus ATCC BAA-2122 TaxID=796620 RepID=E3BL73_9VIBR +-kDLTTTLSELEQKIEGQIGVAVIDTQFSTEW-SYHGDDRFPMMSTFKTLACANVLYDVE +KNKLNMSQKITVTKAGLINWNPITQHFVGGNMSLKSVCGATMLMSDNYAANLALEQVGGP +EGVTQFLRSIGDKATRLDHYEPKLNYVEKNAINDTTTPLAMLRTLQKLLLGNVLNSESKE +QLKFWMTNNMVSDGLARSVLPENWAIADRSGGGVNNSRTLTAMIWSKERKPIFIGIFIAN +SKSELSELNKVVANISHEIFTKy +>[subseq from] Beta-lactamase n=1 Tax=Aliivibrio finisterrensis TaxID=511998 RepID=A0A4Q5KKQ4_9GAMM +---TLETVEAIELSSSSTIGISVLDTATDTTW-SYKGDQRFPMMSTFKTLLCAQMLYNSS +NDLLDKEALTRVTQESIIPWSPITEKFIGETISTESACEATMLMSDNTAANIVLAQTGTP +TSLTLFLRLIGDDITRLDRIEPELNEAQKGDVRDTTTPNAMTNTLNELLFGQTLTTADKN +TLKGWMVNNKVSDPLLRSILPRNWSIADRSGAGGFGSRGITAVLWNEKRAPIIISIYLTQ +TNLDMAARNQVIVEVGNAIFKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0008D9D9B1 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +TKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Plantibacter sp. T3 TaxID=2653161 RepID=A0A653P6B8_9MICO +------EFQALEAEFSARVGVSAVDTGTGARL-SYRADERFGYASTIKALAAAVFLHEVR +--GSARDEVVTWSAEDVEEYSPVTSEQVETGLTLSQLAEAAVRRSDNTALNLVLARIGGP +AALDAALVALGDEVTEVVNAEPLLNVIEPGSTDDTTSPAAFTDNLTRLVDGSYLESADRA +TLLAWMSGNATGDTLIRAGAPAGWQVADKSGGAG-GMRNDIAIIDRPGGDPIVLTILTNT +LDPDAEYDDALVAEAARVALAAf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00071DDF29 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDALIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Uncharacterized protein (Fragment) n=2 Tax=marine sediment metagenome TaxID=412755 RepID=X1R6W8_9ZZZZ +------------------------------------------------------------ +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGVGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Subtercola boreus TaxID=120213 RepID=A0A3E0VE47_9MICO +----TAALQDLEQQFGARVGVSAVDTGTGEQL-SYRADERFGYASTLKVFAAAAFLHDVP +--ASERQTVVTFTADDVEAYSPVTAENIETGLTLSQLAEAAVRRSDNTALNLILERLGGP +AALDATLSSLGDDTSEVVNSEPALNAIEPGSTEDTSTPAAFTADLSRLIDGSYLAPDDRT +ILLDWMTGNTTGDTLIRAGAPSGWSVADKSGGAG-GIRNDIAVVTPPGGHLIVVTIFTNT +LDPEAAYDDALVVGVARAVL--- +>[subseq from] Beta-lactamase n=12 Tax=Staphylococcus TaxID=1279 RepID=T1YC08_STAAU +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00066E76D2 +---HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKNDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium yanoikuyae ATCC 51230 TaxID=883163 RepID=K9CXK9_SPHYA +--------KEIEEETGGRMGIALVDREGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ +GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAEAAVEVSDNSAANLLLPMLGGP +EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDM-QAADAD +RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR +PTVDDKKAEAAIAEAAHSAL--- +>[subseq from] Beta-lactamase class A n=3 Tax=unclassified Pseudomonas TaxID=2583993 RepID=A0A2U1G8F3_9PSED +----DDDFAKVERESGGKLGVYVLDTGSNAHF-GWREDSRFPFCSSFKAPLAAFVLWLSD +QGRLALDQVVRYGEPDLLPYAPTTRANVKNGMTIDALCAAAVLLSDNTAANLLLRETGGP +QALTEWMRWQGDSDFQLSDNEPKLNLSRFADAANTTTAKAMAGSFSRFLSGPLLTPASQA +RFKDWILANQTGAKRLRAGLPAAWQVGDKTGTFNEGSTVDIAAAWPGARKPIIISAFSTD +TP-DTQSGERALAAIARLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. PAMC28499 TaxID=2565554 RepID=A0A4P7QPD3_9SPHN +--------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ +GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAEAAVEVSDNSAANLLLPMLGGP +EGLTSFIRAHGDKITRLDRIEPDLNENVAGDPRDTTSPAAMAGLMGRLLFRDM-AAADAD +RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR +PTVDDKKAEAAIAEAAHSAL--- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=A0A2S6DXH3_STAHA +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADRSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase class A n=1 Tax=Frigoribacterium sp. PhB118 TaxID=2485175 RepID=A0A3N2HXV4_9MICO +--EVEAALADLETRYDARIGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLEATD +--DADLDRVVTWTQAEVDAYSPLTSTHVADGLPLRQLAEAAVRKSDNTALNLVLAELGGP +AGLDAALAAQGDGVTDVVHGEPELNRLTPGSTADTTTPAAFTATLARISDGDWLAADDRA +TLLEWMSGNATGDTLIRAGAPDDWQVADKSGGAG-GIRNDVAIVVPPSGDPVVISVLTTR +NDPAASYDDALVAAAAEVAL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus warneri TaxID=1292 RepID=UPI00031E6BFA +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKNKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. VKM Ac-2803 TaxID=2609256 RepID=UPI00135CEE5E +---VSAELAALESEFDARIGVSAVDTASDRRV-SHRQDERFGYASSIKALAAAQFLRAVP +--AAERDEIVTWTASDVEAYSPVTSESIGDGLPLSELVEAAVRESDNTALNLVLARLGGP +AALDRGLEELGDTTTEVVDEEPALNTIEPGGTANTTTPSAFTAALGAVALGSALPPEDRA +LLLDWMSGNATGDALIRAGAPSGWGVADKSGGAG-GIRNDVAVVTPPEREPIVITVLTER +NDRDADYDDALVARAAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. YZ-8 TaxID=2319844 RepID=UPI0013CEC704 +-----PQFAALEKASGGRLGVSVFDTRTGSIT-GHRAAERFTMCSTFKLPLVAAVFAAAD +AGAIDLNRKLSFAASDLPGNSPVTRANLARGMSIVDLAEAAQSVSDNGAANLLLKHIGGP +AALTAFFREAGDPTSRLDHYEPELNYSHGTDIRDTTTPAAMAVLLSGIFTGSLLKPASRD +RLIAWTIATKTGTHRIRAGLPSDWRAGDKTGTMTASKYNDVAIVWRRETTPFVVSVFYEA +PVDAVSVQEAVIAQAGKLAAE-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007697B1C +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYTSRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044CCF21 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=3 Tax=Terrabacteria group TaxID=1783272 RepID=A0A507SR92_9STAP +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=6 Tax=Staphylococcus aureus TaxID=1280 RepID=M5APG0_STAAU +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSSILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase class A n=1 Tax=Rathayibacter sp. PhB179 TaxID=2485197 RepID=A0A4R1VDM7_9MICO +---VSAELAALETEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKALAAAEFLRSVP +--VGERDEDVTWTAADVEAYSPVTGESIDGGLPLAQLAEAAVRRSDNTALNLVLDRLGGP +AALDRALEQLGDTTTDVVDEEPALNTIAPGSTANTTTPAAFTADLTAVALGEALPSADRA +LLLAWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDIAVVTPPGRDPIVLSVLTSR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Beta-lactamase n=1 Tax=Hydrocarboniphaga daqingensis TaxID=490188 RepID=A0A1M5ND10_9GAMM +---ATAALQQLQQRSGGHIGVQVIDGTTGRRF-GLNTEQRFAMCSTFKLPLAALVLREAE +TAGLRLDTVLRYTRDDLVPHTPVTGAHLADGMRIVDLAEAAQVTSDNLAANLLIAALGGP +AAVTARFRAIGDEVMRLDRIEPELNRVPPGDLRDTTTPDAMARTVLRLFSSPVLGAVSQQ +WLRQWMQATQTGAARLRAGLPSHWAVGDKTGTALAHQHHDVAVIWRAAAAPVVIAAYYEA +PVADRAADDAVLAEVGRIVA--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000F8A1D02 +----AKKLNDLEKKYNGHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00091DB3E1 +---HAKELNNLEKKYNANIGVYALDTKNGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DE17FA6 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKAKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00069FEFB0 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPNNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A3G2UN47_SPHYA +--------KEIEEETGGRMGIALVDREGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ +GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP +EGLTSFIRAHGDKITRLDRIEPDLNENIAGDPRDTTSPAAMAGLMGRLLFRDM-AAADAD +RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR +PTVDDKKAEAAIAEAAHSAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia harenae TaxID=358707 RepID=UPI00082BF5B9 +---LDSALAAIQDRHSVRVALYARY--RDRTV-AHRASEPIAMCSTFKAYAAAAILRLES +EGALRLDETVPVRPADIVVNSPITEAAQGTDLSYAQLCAAALTRSDNTAGNLLLRRIGGP +AALTAFARTLGDRATRLERWEPDLNLAERDTLADTTTADGLATGYAALLLGTALPPAQRR +TLTDWMAASTTSARRIRAALPPGWTAADKTGGGNYGTVNDAGVLWSPDGTPLLLVLLTDS +TTGDVTPADAALAEATTAVL--- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=2 Tax=Brevundimonas sp. Bb-A TaxID=2560058 RepID=A0A5P9KRN8_9CAUL +-------LNDLETRWGGRLGVAALDVGSGVRA-LWRSQERFPFCSTFKPFLAAAILQRVQ +RDEERLDRPVRITSADIIPHAPVTEKAVGRTLTIRELMQAAVEVSDNPAANILIREMGGI +GVWRSWWPTFGDTTTVISRLEPDLNTALPDDPRDTCLPEQTVANIREMAFSDRLTPAHDA +LLHGWLTASPTGPNRIKAGAPEGWSVAHKTGSGARGTTNDVGMLTPLSGSPVIIAAYFTG +AAATEDQRDAVIAEATRRALK-- +>[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio sp. (strain EJY3) TaxID=1116375 RepID=UPI000243B683 +--KLHEDVSLLEQQISGRIGIAVWDTQTDKHW-AYRGDERFPLVGTFKTLACATMLSEMD +TGILKKNATAIVEKRDMVMWSPIMDKLAGQNVRIEHACEAAMLMNDNTATNLVLSEIGGP +KSVMLFLRTIGDKATRLDSAEPSVNEAMPGDKHDTTTPNAMVNTLETLIDGDALSYESRI +QLKIWMQDSKVSDPLMRSVLPSGWSIADRSGAGGNGSLGFNAIIWKENHKPVYISIYLAE +TELSLQAREQLIAQISQLILYKy +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus warneri TaxID=1292 RepID=UPI000D1E8561 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000451FD27 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNIINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI000493EF21 +---HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVISKf +>[subseq from] Beta-lactamase n=22 Tax=Bacteria TaxID=2 RepID=D2JEK2_STAAU +---HAKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=UPI00069DB509 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPISEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0013A6D267 +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVVFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. VKM Ac-2760 TaxID=2609253 RepID=UPI0013194C65 +---VSAALGALEAEFDARIGVSALDTGSGTRV-AHRADERFGYASSIKALAAAQFLRSVP +--AAERGEVVTWTAADVEAYSPVTSESIENGLPLDRLAEAAVRRSDNTALNLVLDRLGGP +AALDRGLEELGDTVTRVVNEEPALNTIEPGSTDDTTTPAAVTADLAAVTLGDALSAADRA +LLLDWMSGNATGDQLIRAGAPEGWTVADKSGGAG-GIRTDIAVVTPPGRAPIVLSVLTAR +NDPDATYDDALVARAAAAVL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Rathayibacter festucae DSM 15932 TaxID=1328866 RepID=A0A3Q9URS7_9MICO +---VSAELAALEAEFDARIGVSAVDTGSGRQV-LYRQDERFGYASSIKALAAAEFLRSVP +--ADERDEIVTWTAADVEAYSPVTSESIDGGLSLAQLAEAAVRRSDNTALNLVLDRLGGP +AALDRALEQLGDTTTDVVDEEPALNSIALGSTANTTTPAAFTADLAAVALGEALPSADRA +LLLDWMSGNATGDALIRAGAPQGWTVADKSGGAG-GLRNDVAVVTPPGRDPIVLSVLTSS +NDPEADYDDALVARAAAVVL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000B953FF4 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Microcoleus vaginatus FGP-2 TaxID=756067 RepID=F5UQ44_9CYAN +-------------------------------V-TLKGNQQFPMQSVYKFPIAMAVLAQVD +QGKLKLHQKIRVETSDVLQGSRILDEKSQGMFILAELLKYMVSESDGTSCNVLLRQVGEP +RIVTEYLRSLGINDIVVANTEKELAQDPAVKYRNYATPDATVVLLRALHEGKGLSKSSQA +LLLQLMTQTTTGPKRIKGLLRDGTVVAHKTGTSSTAATNDVGLVALPNGQHMALAVFVSD +SPANDAIREEVIAKVTKVAWDEw +>[subseq from] Beta-lactamase n=3 Tax=Staphylococcus TaxID=1279 RepID=A0A317YTV6_STAPS +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGIPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dyadobacter sp. 3J3 TaxID=2606600 RepID=UPI00135883B8 +--IFRQEIDKIITASKSDVGVAIMSLEDKETF-LFNEGHKYPMQSVYKFPLAMAVLDQVD +KGKLSLNQKIHVTKKDLLPWSPLREKYPNGEIKVSELIGYAVANSDNNACDLLFRLVGGP +KKVDQYIHSLGIKSIAIATTEEEMSKAWNVQFKNWCKPRAMLRLLDLFYKGKNLSKASTN +FLMKTMTETTTGPNKIKGLLPKNTKVAHKTGMSGTAASNDVGIITLPNGEHVAVVIFLAH +TKLDEKSRDAVMAKISKQAYDYf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044F47DE +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIDASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000CD2E5C5 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKLTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella sp. TaxID=576 RepID=A0A2P1MSM1_KLESP +----------------------------------------------SKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVLIFS- +----------------------- +>[subseq from] BETA-LACTAMASE n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0000112162 +-----KELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELQYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] ARL family class A beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=UPI000DCC1856 +----AQGLTKLEHKNDATVGVYGINTATGQTY-SHNADTRFAYASTFKAITSGLLLQQNS +--PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNIITEQLGGL +DQISSRLQALGDTTTNSQRYEPELNNYDPQSTADTSTPRATAHNLQKLLTTDAVAPQQRK +FLQNLMFNNKTGESLIKKGVPNSYKVGDKSGQGTYGTRNDVAVIYPKHQKPIILVVFTKH +QQQDAQPQDELVAQAARHAIH-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0002F8E3C7 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTLKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis lindanitolerans TaxID=2054227 RepID=A0A2S8B442_9SPHN +--ALARTLTAIERRWGGRLGVAVTDTTGRLLF-GQRADERFAMCSTFKLLLAGQVLHDAA +NGGLALDTSLPLVETDLLPHSPYSETQLAAGLRLGSAAEHSVKISDNAAANLILKATGGP +PGFTRHMRAMGDAVTRLDRTEPDLNENVPGDPRDTTSPAAMAKSGATLVYGDYLDADGRR +TLRSWLVGSTTGRARLRGGLPPAWIAGDKTGSCGT-AYNDVAFVEAPDGGRYMVAAYLDR +PTVNGDAADAILAEVGRAVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Georgenia sp. ZLJ0423 TaxID=2483799 RepID=UPI000F08E1D2 +--DITADLDALETEFDARVGVSALDTETGRSV-EYRAEERFGYASTLKVFAAAELLREVP +--PEEREARVVWTQEEVDAYSPVTSEHLDGGLTVAELAEAAVRESDNTAMNLVLDRIGGP +AGLDAGLAALGDETTDVVSNEPSLNEVDAGGTRDTTTPAAFTAALDALLQPRNLAPDDLA +TLLDWMSGNATGDALIRAGAPADWVVRDKSGGAG-GIRNDIALVTPPGRAPIVVTVLTEK +NDRAAEYDDELVARVAEVVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. GV013 TaxID=2135688 RepID=A0A4R7DJW1_9SPHN +----SARLAAIERRGGGRLGAYVLDTGSGRGF-GWRAAERFAMCSTFKLSLAAWLLREID +AGRIAGDEMLGFGRGDLLPNSPVTGARVATGMTVLDLAEAAQKTSDNLAANLLMRRLGGP +AGLTAFWRSLGDRTSRLDRYETDLNFVPRGDRRDTTTAAAITATAARFLTGPLLTPASRK +LLLRWMAETTTGAHRLRAGLPAGWRGGDKTGTGMPTKLNDIAILYPPAGSPLVVTAFYEP +AGDPLPAHEAVLAQVGALAT--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000E011143 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRFKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A326KX59_9CAUL +----DLHLSDLEGRHGGRLGVAALDVASGRQA-LWRAQERFPFCSTFKAFLAAATLQRVQ +RGEEDLERRVRVTRADMIPHAPTTGPAVGRDLSIRQLMQAAVELSDNPAANILIREMGGI +GVWRQWWPSFGDTTTLISRLEPELNTALADDPRDTCLPAQTLANIRLMAFSDRLSPAHDA +LLHDWLVASPTGPNRLKAAAPQGWTVAHKTGTGMNGTANDIGMMTPVSGAPVLMAVYLTG +ATATDDQRDAVIADAGRRAL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0004501CAD +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] class A beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=UPI0005E46BD2 +--SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLAAAVLGRSQ +SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL +AMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRE +QLALWLKGNTTGAATIRAGAP--------------------------------------- +----------------------- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000768EB39 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKHLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI000D1CD33A +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKKGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0004470F0D +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELRDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0002506D50 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSKPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522QWW8_9BACT +-sSLQQKIAHICQSKHAVVGVAIMNLETGDTL-TYNGEKHFPMQSVFKLPLALAILSKVD +NGIFSLDQSVFISKNDLLPWSPLREKYPDGNLPLSELLQYTVAQSDNNGCDILFGLIGGT +GKVNTCIRQLRIKNIVIAATEVEMHKEWNVQFSNWATPYAMVKLLDIFYKGHILSPKSRK +FLLKTMENTVTGTDKIKGLLPPGTIVAHKTGSSDRNADNDAGIVTLPNGRHFAIVVFITH +STESDKTNARTIAEISRVVWDYf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0005DC5A34 +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Listeria grandensis TaxID=1494963 RepID=UPI00098CFB13 +-----------------------MDTASNKTI-GYNDQERFAYCSSFKAIAGGILLKNLT +--LEQLNKRIHFKKEDLIDHSPITEKHTEDGMTLKEIINAAMTYSDNTAANLMLHELGGP +KAYQKELVKIGDTVTQSDRYEPELNSAVPGDKRDTTTPEAMAKNLAFLVKKGNMPTDNFN +YFKQTLIDNTTGDKLIRAGVPEGYIVGDKTGSGSYGTRNDIAVIYPKDKKPLVWVIYSKK +DTEDAEYDDQLIADAAKVLSKYf +>[subseq from] class A beta-lactamase n=1 Tax=Carnobacterium divergens TaxID=2748 RepID=UPI001072CA79 +------NFEKLEKKYEATLGVYGLDTETNKVV-AYNENQRFSFASTYKALAGGLVLNESS +--WDELNQTIMIKKEDLVTYSPITEKYVDIGIPLKELISAAIQYSDNTAGNFLFKQLGGP +KGFQTKLAELGDYTTDSSRFETELNEATPGDIRDTSTPKEIALDLKKVAIDHKLPTDKLE +FYKKQLIENTTGSKLIRAGVPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK +EQQESDYNDALISETAKIVSNDf +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A5C8X378_STAAU +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=D2JD74_STAAU +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis sp. CF398 TaxID=2135738 RepID=A0A2T5XKH5_9CAUL +--SLAEWCAELEVQTKQRIGVYVISSDTVEEE-GHRWDEPFAMCSTFKWVLAAAVLKFVT +DGALRLDQSVPFSEVDILEHAPVVRKNLPKGLTVSELCAAAVSVSDNSAANLLLPLVGGP +AGLTHFVRSLGDNVTRFDRIEPALNTNEAGDPRDTTTPKAMARLLHKVFFGDVLPPASVS +LLKQWMVDATTGRDLIRSGVPKTWKVGDKTGRGANGALNDVAIVWSASGVFDLVCVYTTG +GQLTDPERRQVLARIGRYA---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BF4199 +-----SPLAEIERRNGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYSENDLIFTSPVTKANVAHGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRV +RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLFVAIYYDA +PGVSLDAREAVLREAGSAFV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A649UI95_KLEPN +-----------------------INTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLADLSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLTTAIPGDPRDTTSPRAMAQILRNLTLGKALGDSQRA +QLVTWMKGNTPGAASIQAGLPASWVGGDKTGSGGYGPTNDIPGICPKDRAPL-------- +----------------------- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI00080B5E3D +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI001068BA96 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKFISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A351CXV7_9GAMM +---LMTKVKAIENQLDARIGVSIYDATHNQHW-HYNGDTRFPLMSTFKTFACAKLLVDVE +CGLQSLDTSSVITTNAIITWSPITEKLVGERISLKQACAAAMTMSDNTAANIVLTGIKGP +KALTQFMRSIGDDVTRI---EPGLNEALNGDKRDTTTPNAIVKSLHLLLFGNVVSENSKA +LLKQWMIDNKVADSLLRSVLPKSWSIADRSGAGGSGSRGITAMVWSAERPPLMISIYITQ +TGAPLALRDKAIADIGEAIFNLy +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00066EC614 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGFPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00138DD222 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLTKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. VKM Ac-2801 TaxID=2609255 RepID=UPI0013203677 +---VSADLAALEREFDARIGVSAVDTGSGRRV-EHRADERFGYASSLKALAAAEFLRTVP +--AAERDDVVTWTAADIEAYSPVTEASTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILTSR +NDPEADYDDALVARAAAVVL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012908D08 +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFDKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus sp. HMSC073C02 TaxID=1739360 RepID=UPI0008A62F34 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=UPI001374BA6A +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDRPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A0J9D038_SPHYA +--------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ +GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP +EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDM-QAADAD +RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR +PTVDDKKAEAAIAEAAHSAL--- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium sp. LF-16 TaxID=2185111 RepID=UPI000F091F18 +--------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ +GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP +EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDM-QAADAD +RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR +PTVDDKKAEAAIAEAAHSAL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. YZ-8 TaxID=2319844 RepID=A0A494TMV4_9SPHN +-----PQFAALEKASGGRLGVSVFDTRTGSIT-GHRAAERFTMCSTFKLPLVAAVFAAAD +AGAIDLNRKLSFAASDLPGNSPVTRANLARGMSIVDLAEAAQSVSDNGAANLLLKHIGGP +AALTAFFREAGDPTSRLDHYEPELNYSHGTDIRDTTTPAAMAVLLSGIFTGSLLKPASRD +RLIAWTIATKTGTHRIRAGLPSDWRAGDKTGTMTASKYNDVAIVWRRETTPFVVSVFYEA +PVDAVSVQEAVIAQAGKLAAE-- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=UPI00131F4AB6 +--------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAVAVLIGAQ +GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAEAAVEVSDNSAANLLLPMLGGP +EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDM-QAADAD +RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR +PTVDDKKAEAAIAEAAHSAL--- +>[subseq from] Beta-lactamase class A n=2 Tax=Chryseolinea serpens TaxID=947013 RepID=A0A1M5TPR8_9BACT +--RLRGEMARITGSLSANVGVAVLNLDTGDTL-TWRGHNRFPMQSVFKFPLAIMVLHEID +RGALTLDQKIHLRKEDMMLWSPMATKYPEGNLALSEILRYTVSQSDNSGCDVLFRLMGGP +RKVNDFLHGLGITQIAIAATETEMHASWPVQFTNWCEPAAMTALLKQFDRGKILSPSSRE +FLWKLMVETSTGPKRIKGLLPEGTVVAHKTGTGDLGAFNDVGIVVLPDGSHVAIVVYISG +TKKDAAKLDLVIAQISRAVYDQy +>[subseq from] class A beta-lactamase n=1 Tax=Zymomonas mobilis TaxID=542 RepID=UPI0009BE827B +---------EYEQATGGHVGIYAQNIATGKSL-AWRANERFLMCSSFKVSLVASVLLRCD +RGQDSLDRIISYKPEDIGDYAPFAKAHLDKGMSVAELCQEAIEQSDNFCANKLLERSGGV +LALTAFWRQLGDNQSQLDNIEPFLNETPYGGIENTTTPIAMAHNLQKMLLGSLLSPSSRD +RLTGWMVRCQTGSQRLRAGLPKNWVIADKTGTNGHDAASDIAILWPQPDKAIILSVYVWG +GTPTKDQLLSLFSKIAH------ +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044A83D9 +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSEKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A2Z6TBQ6_BURVI +-----SPLAEIERRSGGRLGVFAIDTGPGRTP-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALARFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA +RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA +PGVSMDAREAVLREAGAAFVQ-- +>[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus epidermidis TaxID=1282 RepID=A0A659CEW2_STAEP +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0002C9C928 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00026BF532 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000D743258 +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKIKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. S-NIH.Pt3_0716 TaxID=1920124 RepID=A0A430D695_9SPHN +--------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ +GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP +EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDM-AAADAD +RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDIALVKSPAGEEYILAIYLDR +PTVDDKKAEAAIAEAAHSAL--- +>[subseq from] Beta-lactamase n=35 Tax=Bacillales TaxID=1385 RepID=D2J7V8_STAAU +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044DEC22 +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1C7 TaxID=2080540 RepID=UPI000CE86DE7 +---VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKVLAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEETTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSTR +NDPEADYDDALVARAAAVVL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000452D05E +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQAKYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] UPI0012F4779E UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0012F4779E +-nNTRQKVNEIAATARGHVGVAMMSLENGDTM-TLNGNDHFPMQSVFKVPLAIAVLDQVD +KGKLSLDQVIHITKKELLPWSPIREKYPEGTLKLREVLAYTVSQSDNNGCDILFNLVGGT +AYVEQYIHGLGVDSMAIKANEERMASAWKVQYTNWSSPLATLQLLKGIHTGKYLSKASND +FLLKIMKETTTGPKRLRGMLPADAVVAHKTGSSDTAATNDAGIVTLPDGSHLAIVVFVSD +TKVNEAIREGVIARITRLFWD-- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=UPI0008468D2B +--------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ +GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP +EGLTSFIRAHGDKITRLDRIEPDLNENVAGDPRDTTSPAAMAGLMGRLLFRDM-QAADAD +RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR +PTVDDKKAEAAIAEAAHSAL--- +>[subseq from] Beta-lactamase n=1 Tax=Aliivibrio finisterrensis TaxID=511998 RepID=A0A4Q5KQK1_9GAMM +---TLETVEAIELSSSSTIGISVLDTATDTTW-SYKGDQRFPMMSTFKTLLCAQMLYNSS +NDLLDKEALTRVTQESIIPWSPITEKFIGETISTESACEATMLMSDNTAANIVLAQTGTP +TSLTLFLRLIGDDITRLDRIEPELNEAQKGDVRDTTTPNAMTNTLNELLFGQTLTTADKN +TLKGWMVNNKVSDPLLRSILPRNWSIADRSGAGGFGSRGITAVLWNEKRAPIIMSIYLTQ +TNLDMAARNQVIVEVGNAIFKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012AFF105 +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=54 Tax=Staphylococcus aureus TaxID=1280 RepID=Q60250_STAAU +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0002CCA91D +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=V9SHK8_STAAU +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia bannensis TaxID=765414 RepID=A0A658LAD8_9BURK +---ADSPLSDIERRHGGRLGVFAIDTGSCRTL-SHRAEERFLMCSTFKGLLAAQILARVD +GGAERLDRLVHYTEKDLIFTSPVTKANVAGGLSIDALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTITRSDRYEPESNRY--RGVLDTTTPKAIATTAQRLLLGDALSASSRA +QLERGMADCKPGLNRIRAVLPAGWQAADRPGTSVESETNDYALVRPPGRAPLLVAAYYDA +PGVSMEAREAVLREAGTAFV--- +>[subseq from] Beta-lactamase n=48 Tax=cellular organisms TaxID=131567 RepID=A0A0Y2CSL2_STREE +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Frigoribacterium faeni TaxID=145483 RepID=UPI00141BC253 +--AVAADLAALEAEYDARVGVSVVDTGTGATL-SHRADERFGYASSLKALAAAQFLHDVP +--ADQRDEVVTWTAADVEAYSPVTSEHVADGLPLVQLAEAAVRRSDNTALNLVLARIGGP +AGLDAGLAAIEDRTTEVVGTEPDLNTIEPGSTDDTSTPTAFTADLVALLDGRWLADDDRA +LLLDWMSGNATGDTLIRAGAPSGWVVADKSGGAG-GIRNDVAVVTPPGRAPVVVSVFTSR +NDPDADYDDALVARTAALVL--- +>[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=3 Tax=Staphylococcus TaxID=1279 RepID=A0A6B5MC16_STAAU +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +TKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00138DD742 +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Pseudarthrobacter sulfonivorans TaxID=121292 RepID=A0A0U3P9C4_9MICC +---LTRRMEVLEREFSARVGLFAVDGPTGAKF-GHRADERFAMCSTFKVYAAAAVLQRAS +EGLADLSRGIRIDPADVVVNSLECADFAGSTLPLKWFCKVALTHSDNSAGNQLLRELGGP +AAIGTYARSLGDTESRLDRWEPELNNAERGDPRDTSTPRALAHGYRKLLLGDALSPLVQA +QMTGWMLANGTSGQRMWAGLPDGWTSADKTGAGLFGTVNDVGVVRNPAGEPLVLSILTDT +ASADTPGSNELVAAITRAVT--- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=D2JBV1_STAAU +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGIPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Nesterenkonia sp. F TaxID=795955 RepID=UPI000255C8A3 +-----AAVEQLEQEYDARVGVSMIDLGDGSTL-THRSDERFGFASTMKAFAAAALLHSTS +--AEERRQRVQWTSADLDAYSPVTEQAVETGLTLGELAEAAVRESDNTAMNLILEHLGGP +EGLQRSLEGLGDSVSRPVDVEPELNEIIPGDAANTSTAGALAGNLERLVDGDWLDEDDRR +VFMEWMSGNPTGDTLIRAGAPEDWSVAEKSGGAG-AIRNDAAVLQPPEGAPIVLVVLTER +NDADDEYEDALVAEVAGAVL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus warneri TaxID=1292 RepID=UPI00066C5419 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKTNKN +FLLDLMLNNKNGDTLIKDGIPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio finisterrensis TaxID=511998 RepID=UPI00101EAE15 +---TLETVEAIELSSSSTIGISVLDTATDTTW-SYKGDQRFPMMSTFKTLLCAQMLYNSS +NDLLDKEALTRVTQESIIPWSPITEKFIGETISTESACEATMLMSDNTAANIVLAQTGTP +TSLTLFLRLIGDDITRLDRIEPDLNEAQKGDVRDTTTPNAMTNTLNELLFGQTLTTADKN +TLKGWMVNNKVSDPLLRSILPRNWSIADRSGAGGFGSRGITAILWNEKRAPIIMSIYLTQ +TNLDMASRNQVIVEVGNAIFKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI000E0530A9 +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKNDKPNDKLISETAKSVMKEf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=bacterium HR10 TaxID=2035405 RepID=A0A2H5W2M9_9BACT +--RLEREIARLAGIAGGVVGVAALHLESGRRV-ALNGAERFPMASTYKVPIAVQVLTKVD +HGELTLDQMITLEPADLSPGSGTLSDLFRAPLSVRNLLELMLLISDNTATDVLLRVAGGA +EAVTARLRELGIEGVRVDRPTKQVIARFDEDPRDTATPEAMVALLEQIYRGRALKRETTE +LLLDILQRCRTGEARLKGLLPPGTEVAHKTGTIG-GTTNDVGILTLPGDGHVAIAVFVKS +SDKDIPTRERAIAEIARAVHDFf +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. PhB25 TaxID=2485205 RepID=A0A4R8C001_9MICO +-eRVRRALAGLERQYDATVGVVATDTVTGETV-AYNGDRRFGYASTIKAFAAAQFLRSVP +--ADARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP +SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALTTVLDGSTLDRADTA +LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR +NDPDAAYDDALVARSASAVLDAf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI000344EF30 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus TaxID=1279 RepID=A0A6B9HRU2_STAEP +---HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRFKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVISKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007CA6CEB +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIPNGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=9 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0002CB0DE9 +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTHPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007CA7451 +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFIYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A084EFL3_SPHYA +--------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ +GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP +EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDMASA-DAD +RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR +PTVDDRKAEAAIAEAAHSAL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000A33BBCC +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Subtercola boreus TaxID=120213 RepID=A0A3E0W7D4_9MICO +----TAALAALEQQFGARVGVSAIDTVTGEQL-SFRADERFGYASTLKVFAAAAFLHDVP +--ASERQTVVTYTAADVEAYSPVTSESIGTGLTLSQLAEAAVRRSDNTAMNLILNRLGGP +AALDAALREQGDDVSEVVNSEPALNVIEPSSTDDTSTPAAFTANLSRLIDGPYLATDDRA +ILLEWMTGNTTGDTLIRAGAPSGWNVADKSGGAGS-IRNDIAVVTPPGGHPIVVTIFTNT +LDPDAAYDDALVTGVARAVL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000E0D0565 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNANKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007C474B1 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYIGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. ARR65 TaxID=1040989 RepID=UPI0004657AD0 +----EASIAEIEKRHGGRLGVFAVDTGTGRTL-AHRADERFLMCSTFKGLLAALVLARVD +AGQEALSRMIPYGEKDLIFTSPITKANVGKGLSVGDLTKALLEASDNTAAILLMRSAGGP +SGLTKFVRGLGDTVTRSDRYEPKSNED--SGILDTTTPRAIVGSVRKILLDNVLKPQSRQ +RLEAGMIACTPGLKRIRAALPSDWIAGDRPGTSTKGESNDYAIVRPPGRAPLLIAAYYNA +PKLSMAEREVVLRETGSAFV--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=UPI000A0FE521 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1C2 TaxID=2080535 RepID=UPI000CE85CFF +---VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADQRFGFASSLKVLAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEKTTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSTR +NDPEADYDDALVARAAAVVL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI00069F7719 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DA745DA +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPLLEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00066B9C67 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGN +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=4 Tax=Staphylococcus TaxID=1279 RepID=A0A0H2VHE7_STAES +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQAP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase class A n=1 Tax=Frigoribacterium sp. PhB160 TaxID=2485192 RepID=A0A3N2ID41_9MICO +--RVDAALAALEAEFDARVGVSAVDTGDGRSI-GHRADERFLYASSLKALAAAALLDVTT +--ADDLAERATWTSADVAAYSPVTELHVVGGLSYAELAEAAVRKSDNTALNLVLDRVGGP +AALDAWLTDLGDDETEVVDQEPELNRPTAGSDANTTTPAASTADLRAVAVGDALAADDRA +QLLDWMSGNATGDALVRAGAPDGWVVADKSGGAG-GVRNDVAVVTPPGREPIVLSVLTAR +ND--ADYDDALVARAAAAVLAEf +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas nasdae TaxID=172043 RepID=A0A0B4CQL5_9CAUL +-------LSDLETRNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKMYLAAATLLRAQ +AGQERLDRRIPITTADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP +SAMQTFYRGIGDDSTRSDRFEPEMNRL--DGDKDTILPNQSVANLQRLFLDPALTAASRD +LLLQWMTDTPTGQNRLRAGTPADWRVAHKTGTGGYGPTNDIGLLYPPDGQPVIVAAYYHA +TGTSDDANAAVIAEATRRAL--- +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / NCIB 11800 / UQM 2034) TaxID=485918 RepID=C7PRN9_CHIPD +-nNTRQKVNEIAATARGHVGVAMMSLENGDTM-TLNGNDHFPMQSVFKVPLAIAVLDQVD +KGKLSLDQVIHITKKELLPWSPIREKYPEGTLKLREVLAYTVSQSDNNGCDILFNLVGGT +AYVEQYIHGLGVDSMAIKANEERMASAWKVQYTNWSSPLATLQLLKGIHTGKYLSKASND +FLLKIMKETTTGPKRLRGMLPADAVVAHKTGSSDTAATNDAGIVTLPDGSHLAIVVFVSD +TKVNEAIREGVIARITRLFWD-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009C0E1A7 +-----SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD +SGSERLDRLVHYTENNLIFTSPVTKANVAHGMSIEALCRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRV +RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLFVAIYYDA +PGVSLDAREAVLREAGSAFV--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044B99BA +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTHPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFIYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. Leaf280 TaxID=1736320 RepID=A0A0S9NL35_9CAUL +-------LSGLETRNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRRIPITAADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP +SAMQTFYRGIGDDSTRSDRFEPEMNRL--DGDKDTILPSQSVANLERLFLDPALTAASRA +LLLQWMTDTPTGQNRLRAGTPADWRVAHKTGTGGYGPTNDIGLLYPPNGQPVIVAAYYHA +ARATDDANAAVIAEATRRAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF9320B +--------AKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYIDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNTTGDNLIRAGVPGGWEVAD-------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Zymomonas mobilis subsp. mobilis (strain ATCC 10988 / DSM 424 / LMG 404 / NCIMB 8938 / NRRL B-806 / ZM1) TaxID=555217 RepID=A0A0H3G2Y5_ZYMMA +---------EYEQATGGHVGIYAQNIATGKSL-AWRANERFLMCSSFKVSLVASVLLRCD +RGQDSLDRIISYKPEDIEDYAPFAKAHLDKAMSVAELCQGAIEQSDNFCANKLLERSGGA +LALTAFWRQLGDDQSRLDNIEPFLNETPYGGVENTTTPIAMARNLQKMLLGSLLSPSSRD +RLTGWMVRCQTGSQRLRAGLPKNWVIADKTGTNGHDAASDIAILWPQPNKAIILSVYVWG +GTPTKDQLLGLFSKIA------- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000CD05570 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGNTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas sp. SPF441 TaxID=2663795 RepID=UPI00129E03D8 +------DLADLEARNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRRIPITTADMINHAPVTERAVGASLTIEQLIKGAVEVSDNPAANLLLKAMGGP +SAMQTFYRGIGDGSTRSDRFEPEMNRL--DGDKDTILPNQSVANLQRLFLDPALTAASRA +LLLQWMTDTPTGQNRLRDGTPANWRVAHKTGTGGYGPTNDIGLLYPPNGQPVIVAAYYHA +TRATDDANAAVIAEATRRAL--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis macrogoltabida TaxID=33050 RepID=A0A0N9UYU2_SPHMC +-----KAIRDLEARSGGRLGIAVVD-ARGKLVsADRGHERFAMCSTFKLLLAGQVLERAA +-KGVSLRTPLAFTRADLVSWSPGTEKRVGPDQQLGMAARDAVVLSDNSAANLILKQMGGP +AAFTAALRRAGDSVTRLDRIEPELNENAPGDQRDTTTPIAMATSAAGYVFGNRLGAGHRQ +QLRGWMIESETGRKRIRAGLPQGWIAGDKTGTCGN-AYNDVAFVEAPDGRKYVIAIYLDR +SAVTGDEASAVIAEATRLTVE-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI00069FA5D9 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=UPI000E240CD7 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGEI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=uncultured Mycobacterium sp. TaxID=171292 RepID=A0A1Y5PKH7_9MYCO +---IEQRIAALEKRHNAFVGLYGQNLDSTQSV-AHRDGDLFAMCSTFKAYASARVLQMAQ +AGELRLTDTVVVDPTLLRANSPRTEPNVGKPMALSDLCAAALQVSDNTAGNLLLRVIGGP +PAITAFARSIGDDRTRLDRWETELNSALPGDPRDTSTPRALGGGILSVLTGTVLDEPHRK +QLEDWMRVNTT--SSVRAGLPPDWTTADKTGSGDFASTNDVGIAFGPHGERVLLAIMTRT +QSNDSPALRDLVAEVTTLA---- +>[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio finisterrensis TaxID=511998 RepID=UPI00124D1EB9 +---TLETVEAIELSSSSTIGISVLDTATDTTW-SYKGDQRFPMMSTFKTLLCAQMLYNSS +NDLLDKEALTRVTQESIIPWSPITEKFIGETISTESACEATMLMSDNTAANIVLAQTGTP +TSLTLFLRLIGDDITRLDRIEPELNEAQKGDVRDTTTPNAMTNTLNELLFGQTLTTADKN +TLKGWMVNNKVSDPLLRSILPRNWSIADRSGAGGFGSRGITAVLWNEKRAPIIMSIYLTQ +TNLDMASRNQVIVEVGNAIFKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI0005DE16E4 +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WU68_9BACT +------AIKQIIQSSKGTVGVAVIGLEDNFSM-TMNDHKRFTLHSVYKFPLALAVLDQVD +KGQLSLDQKLHVTKKDLLPWSPLRDEHPNGGISLSELLGYTVSQSDNNGCDFLFRLLGGT +KNVQTYIRNLGIKDISIAATEEEVAKAWPVQYTNWSRPSAMLRLMVNAYRGKYLSQSSTD +FLWKLMRETSTGPNRMKGLLPPGTVVAHKTGTSGTNATNDVGIVTLPNGKHFAIVVFVAD +STDDQKTREGVIARITKVVWDYy +>[subseq from] Beta-lactamase n=2 Tax=unclassified Curtobacterium TaxID=257496 RepID=A0A4R1SUI9_9MICO +-eRVRRALAGLEREYDATVGVVATDTVTGETV-AYNGDRRFGYASTIKAFAAAQFLRSVP +--ADARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP +SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALTTVLDGSTLDRADTA +LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR +NDPDAAYDDALVARSASAVLDAf +>[subseq from] Beta-lactamase n=1 Tax=Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) TaxID=264203 RepID=Q5NL19_ZYMMO +---------EYEQATGGHVGIYAQNIATGKSL-AWRANERFLMCSSFKVSLVASVLLRCD +RGQDSLDRIISYKPEDIGDYAPFAKAHLDKGMSVAELCQGAIEQSDNFCANKLLERSGGV +LALTAFWRQLGDNQSQLDNIEPFLNETPYGGIENTTTPIAMAHNLQKMLLGSLLSPSSRD +RLTGWMVRCQTGSQRLRAGLPKNWVIADKTGTNGHDAASDIAILWPQPDKAIILSVYVWG +GTPTKDQLLSLFSKIAH------ +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. SGAir0440 TaxID=2579977 RepID=A0A4V1F825_9CAUL +-------LSDLETRNGGRLGFVVQDAATGRKL-GWRGDERFVYCSTFKMYLAAATLLRAQ +AGQERLDRRISITAADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP +SAMQTFYRGIGDDSTRSDRFEPEMNRL--DGDKDTILPNQSVANLQRLFLDPALTAASRA +LLLQWMTDTPTGQNRLRAGTPADWRVAHKTGTGGYGPTNDIGLLYPSNGQPVIVAAYYHA +NRTSDDANAAVIAEATRRAL--- +>[subseq from] Beta-lactamase n=1 Tax=Moritella sp. JT01 TaxID=756698 RepID=A0A137SNQ8_9GAMM +--NIDASLRHIEQQIEGQIGVSVIDTENNTQW-SFNGTERFPMMSTFKTLACANVLYDVQ +HNMLSLTQKINVSKEGLINWNPITQHFIGAQMSLKSVCGAAMIMSDNYAANLALEQIDGP +KGVTAFLRSIGDNETRLDHFEPKVNYVKKGAKNDTTTPVAMMNTIRKLLIGNVLDAESKA +QLQVWMTNNMVSDGLARAVLPKGWKIADRSGGGVNGSRTLTAMVWKKDHKPVFVGIFIAN +SKKTLLELNKVVADISKQVFDKy +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000BA5CE6C +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIGLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WVM4_9BACT +-nELRDRIEQISQAARGRVGVTATVLETGESV-TLNGDRQFPMQSVYKFPIAMAVLAQVD +QGKLKLDRKIRVETSDVLQGSRILDEKSQGMFSLAELLKYMVSESDGTSCNVLLRQVGEP +RIVTEYLRSLGINDIVVANTEKELAQDPAVKYRNYATPDATVVLLRAFHEGKGLSKSSQA +LLLQLMTETTTGPQRIKGLLPDGTVVAHKTGTSSTAATNDVGLVTLPNGRHMAIAVFVSD +SGANNATREGVIAKVTKAAWDEw +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2XPT6_STAAU +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHIXKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI0011A50F1C +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGISKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium ipomoeae TaxID=1210932 RepID=A0A4S8NZ33_9RHIZ +----LETAKSIEARLDLRLGYAMIGPTGEMQH-GYRADERFAMNSTFKALACAAALNRGD +---QVLDMRVTVRKGDILPHSPVTETRIGSTIAIRALCEITLRTSDNAAANLVLKAIDGP +EALTDFLRAKGDDVTRLDRFEPELNEAKPGDPRDTTTPRAMASTIRHLTLGSGLSPAASR +QLDAWMQANAVADGLLRKVLPKGWPIADRSGAGGFGSRGIVALIRPDTGDPVVVAIYMTG +KAHPLKVRDAAIAELGDAIF--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A085K8G2_SPHYA +--------KEIEEETGGRMGIALVDGDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ +GGKFGLEGEIPFTKDDILDYAPVVKRNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP +EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDMASA-DAD +RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR +PTVDDKKAEAAIAEAAHSAL--- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. JUb34 TaxID=2485109 RepID=A0A3N1YFJ2_9MICO +--AVRRALAALEREYDATVGVVATDTVTGATV-AYNGDRRFGYASTIKVFAAAQFLRSVP +--TDARDEVVHWTAADVAAYSPVTEQHVADGLTSAQLAEAAVRMSDNTALNLVLTRIGGP +SSLDAALAELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALATVLDGSTLNSADTA +LLVGWMGGNATGDALIRAGAPDGWVVVDKSGGAG-GIRNDVARVTPPDGDPIVLSVLTTR +NDPDAAYDDALVARSASAVLGAf +>[subseq from] Beta-lactamase n=1 Tax=Brevibacterium siliguriense TaxID=1136497 RepID=A0A1H1QQG5_9MICO +hqRLDEQLTNLEDRYDARVGVSALDTETGEAV-DHRADERFGFASTLKVFAVAELLDRTK +--PDDLEKNVTWTQADVDEWTPVTEKHVDDGLPLDDVAESALRVSDNLAMNIVLDELGGP +EALDDALEKAGDTTTEVTDEEPALNDVEDGSTDNTTTPAAFSAGLRDLLDPQRLSDEDRE +VLLNWMSANETGDSLIRAGAPDGWVVRDKSGHSD-AIQNDIAVVTPPDRQPIVISVMTET +DDPESEDGPALVAAVAEVVLDSf +>[subseq from] Beta-lactamase class A n=1 Tax=Williamsia sterculiae TaxID=1344003 RepID=A0A1N7CSA0_9NOCA +--RLEAQIVTAAARVRADIGVHAVDLASGVTA-DVHSGNRFPILSMFKVYAAAAILRDAR +AGKLSLQTPVRITRADIVSNAPVTSAHVNGTLTMAEIAQAALQHSDNTAGNLMLRQLGGP +AAVNALARSVGDTDTDLERWETALNDAVPGDVRDTTTPRAVATGFRSLLAGDGLQQQDRD +TLVGWMRGSATSAQRFRAQLPAGWTTADKTGSGEFGTTDDGGLLLGPGGRRILLVVQTRS +GTDDSNGYGDLVAEVARLVAQ-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=3 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00045189C0 +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=B8XXQ7_BURPY +---AAATLAQLERTAGGRLGVCALDAASGRRV-EHRADERFPFCSTFKAMLSAAVLAQSV +ARPGLLQQRVTYGKADLVNYSPVAEKHVGAGMTVAELCEATIQYSDNSAANLLMKLLGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLGDTTTPAAMAASMRVLTLGDALPAAQRA +QLVTWLRGNKVGDKRIRAGV---------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Segniliparus rotundus (strain ATCC BAA-972 / CDC 1076 / CIP 108378 / DSM 44985 / JCM 13578) TaxID=640132 RepID=D6Z9W4_SEGRD +----ESAVAALEARHKAHVGVFALDTGSGNTL-EHRADQRFMMCSVWKTLVVGLVLRRAQ +ADPGLLAAVIPADPGPIAEDSPFAKGRLGQTATYSELCGAAIRLSDNIAANILLQQFGGP +PAVTDFVRSLGDATTRLDRYEEEMNYGSPEDLLDTTTARALASTYQKLLLGDALAPPQRQ +QLTDWMEGTTTGLHRIRAGLPAAWRVADKTGTAGQGNANDVAIAWPDGGAPLAISVLTVA +PG-VAKPDDRLLADVASAA---- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus capitis TaxID=29388 RepID=UPI000BFD34D1 +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPSAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Class A beta-lactamase n=1 Tax=Brevibacterium linens TaxID=1703 RepID=A0A144MWY4_BRELN +hqEVEDQLKDLEDRYDARVGVSALDTGSGDSV-DHRADERFGFASSLKVFAVAELLDRTT +--PKELEKNVTWTQADVDEWTPVTEKHVDDGLPLEDVAESALRVSDNLAMNIVLDEIGGP +KALDDALAKAGDTTTEVTDEEPELNDVEEGNTDNTTTPAAFTTDLQSLFDSQRLSDEDRE +VLFSWMSANETGDPLIRAGAPEGWVVRDKSGHSG-AIQNDIAVVTPPDRKPIVISVMTET +NDPESEDGPALVAAVAEVVLNEf +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Bacteria TaxID=2 RepID=A0A2Z4C251_STEMA +-----------------RVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA----MSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGE-------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas vesicularis TaxID=41276 RepID=A0A1Z3U5S2_BREVE +------DLADLEARNGGRLGFVAQDAATGRKL-VWRGDERFVYCSTFKMYLAAASLLRVQ +AGQERLDRRIPITAADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP +SAMQTFYRGIGDGSTRSDRFEPEMNRL--DGDKDTILPNQSVANLNRLFLDPALTAASRA +LLLQWMTDTPTGQNRLRAGTPADWRVAHKTGTGGYGPTNDIGLLYPPNGQPVIVAAYYHA +TRATSDDANAVIAEATRRAL--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WPD0_9BACT +-nELRDRIEQISQAARGRVGVTATVLETGESV-TLNGDRQFPMQSVYKFPIAMAVLAQVD +QGKLKLDRKVRVETSDVLQGSRILDEKSQGMFSLAELLKYMVSESDGTSCNVLLRQVGEP +RIVTEYLRSLGINDIVVANTEKELAQDPAVKYRNYATPDATVVLLRAFHEGKGLSKSSQA +LLLQLMTETTTGPQRIKGLLPDGTVVAHKTGTSSTAATNDVGLVTLPNGRHMAIAVFVSD +SGANNATREGVIAKVTKAAWDEw +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus pettenkoferi TaxID=170573 RepID=UPI0011A6F911 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLVSETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI0011A6976C +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCNVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=E9LZM8_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMISTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVARPL--------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=E9LZM7_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMISTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVARPL--------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. PhB146 TaxID=2485187 RepID=A0A4V2VI26_9MICO +---VRRAIAGLEREYDATVGVVATDTVTGETV-AYNGDRRFGYASTIKAFAAAQFLRSVP +--ADARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP +SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALATVLDGSTLDRADTA +LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR +NDPDAAYDDALVARSASAVLDAf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00066E9885 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. PhB171 TaxID=2485195 RepID=A0A3N1NNN7_9MICO +--AVRRALAGLEREYDATVGVVATDTVTGETV-AYNGDRRFGYASTIKAFAAAQFLRSVP +--ADARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP +SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALATVLDGSTLDRADTA +LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR +NDPDAAYDDALVARSASAVLDAf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0013A6F1A7 +---HAKELNDLEKKYNANIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=2 Tax=Plantibacter sp. VKM Ac-1784 TaxID=199708 RepID=A0A1Y6E978_9MICO +------EFQALEAEFSARVGISAVDTGTGARL-SYRADERFGYASTIKALAAAVFLHEVR +--GSARDEVVNWSAEDVEAYSPVTSEQVETGLTLSQLAEAAVRRSDNTALNLVLARIGGP +AALDAALGALGDEVTEVVNAEPLLNVIEPGSTDDTTTPAAFTDNLTRLVDGSYLEPADRA +TLLAWMSGNATGDTLIRAGAPAGWQVADKSGGAG-GIRNDIAIIDRPGGDPIVLTILTNT +LDPDAEYDDALVAEAASVALAAf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI0004503364 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYTSTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00123182FE +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI000E6806C8 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNVDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=2 Tax=unclassified Xanthomonadaceae TaxID=191676 RepID=A0A2M9EPC5_9GAMM +--DAEQQLLDLQQTSAGRLGVYVLDSETRRHL-ALRADERFGMNSTFKLLLAAVVLRAME +EGEFAADMTLPFSADDLVPHAPVIQARLDNGMHMTELAKAAQLTSDNTAANLLIRQLGGP +EGVTARWRALGDQVSRLDRYETEMNFVPAGEVRDTTTPRAMAETVARLFVGDVLGDGARE +DLKGWMLATETGLKRLRAGFPPGWQIGDKTGSGFEGKTHDVAVIWREGRKPVVIAAYYEA +DAGVRDEDEAVLAGVGRIVQ--- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. 18060 TaxID=2681408 RepID=UPI001356FB3B +-eRVRRALAGLERQYDATVGVVATDTVTGATV-AYNGDRRFGYASTIKAFAAAQFLRSVP +--ADARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP +SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALTTVLDGSTLDRADTA +LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR +NDPDAAYDDALVARSASAVLDAf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI000B7ABC49 +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +VLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000449A5E4 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1F3 TaxID=2080558 RepID=A0A2S5XR83_9MICO +---VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEETTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSTR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga filiformis TaxID=104663 RepID=A0A1G7XDK8_CHIFI +----RKKIHDIALTVHGHVGMAMMSLEDGDTI-TLNGKDHFPMQSVFKLPLAIAVLDQVD +KGKLALNQVIHIRKEDLLPWSPIREKFPEGTMKLSDILAYTVSQSDNSGCDLLFRLVGGT +AYVDKYIHSLGIDNIAIKATEEQASKAWEVQYTNWSSPIAMLQLLKGVHTGKYLSKASNE +FLLKLMTETTTGPKRMKGLLPENAVVAHKTGTSDTAATNDVGIVTLPNGKHYAIAVFVSD +TRADTATREGVIAQLTRLFWD-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas azotifigens TaxID=330920 RepID=UPI000A0033E1 +--AVSDPIAQYERVTGGRIGVYAVNVKTGAKL-TWRADERFIMCSSYKASLAAFVLSRVD +RGEEKLDAAIRYGVRDTKDWGPVSKANLTKGMTVEAMCKAAVEISDGVCANLLLARSGGP +AALTAFLRSIGDGITRVDHYEPQLDRVPSGGPWDSTTPAAMAATLQKMVLGDVLSARSKA +LLTQWLIGNQT-NPRLRGGLPRSWLIGNKTGHSGRDMAGDIAVAWPRPDTPIVIAVYTRE +GRPTEKQFDEVFGGIGRLVAS-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000CE83C01 +---VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEETTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSTR +NDPEADYDDALVARAAAVVL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0013E3154D +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Listeria sp. PSOL-1 TaxID=1844999 RepID=UPI0013CF4490 +--TIESKFKRLEEKYQATLGIYAIDTKTTKEI-TYNQEERFAFTSTYKAIISGIILRNYT +--NEQLNKRIFYTAEDLVTYSPITQDHVSGGMTIREIIHAAITYSDNTAGNLLFNELNGP +KEFQNALEKIGDQVTHSDRYETDLNSAVPSDIRDTTTPTAFLKDLSFLMDPSHMNHEALA +YFKKTLIENTTGDHLIRAGVPDGYIVGDKTGAGSYGTRNDIAVIFSSDMKPFVWIIFSKM +VKKEDQYHDQLIADAAKLLSEYy +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0005E2BA2F +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLLLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=43 Tax=Bacteria TaxID=2 RepID=A0A6B0BAG8_STAAU +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000E018B44 +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPIRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura kijaniata TaxID=46161 RepID=UPI0009FEBD28 +--DLTKALQELEQSYNGRIGAVGIDLATGRTV-GHRADERFPFNSMFKVFACSAVMDKAR +TDPGLMDRVVRWKPADMAGNSPETKEYTDTGMTPAQLCRAGITKSDGFAGNTLLKQIGGP +RGLTAFFRATGDRTSRLDRPEPYLTEWQPGEERDTTTPAAAARTFTKLTTGKVLHPRDRE +RLLGWLKASLAGADRIRAGLPKEWTVGNKSGTGGHGTANDMAIAWPPGAAPIILAVFTNR +TTDDTPHDAKVIQSTATALAK-- +>[subseq from] Beta-lactamase n=1 Tax=Cryobacterium roopkundense TaxID=1001240 RepID=A0A099JG23_9MICO +-sALQTALGELEDQYDARIGLSVTDTADGSTL-DYRGGSRFGYASTLKMLAAAALLDQTT +--PEELDRVVTWSEADVLEYSPVTSEHLDTGLPLGDVAMAAIRTSDNTAMNLMLKQFGGP +AGLDKILEGYGDTVTDVVDNEPGLNTVTIDNTANTSTPRAFTKTLERIVSGEILDDADRS +TLIDWMTGNATGDTLIRAGAPEGWEVADKSGGAG-AIRNDVAVVIPPDGIPLVITVFTTR +NDPDTAYDDALVAETARLAL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0011D1C5AC +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYAATSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus sp. HMSC74G01 TaxID=1608906 RepID=UPI0008A94009 +---HAKELINLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium PA4 TaxID=2015572 RepID=A0A257EJA8_9PROT +--ALRAAVAETERSAGGPLGLMVRDTGSGASF-RHRADQRFPLCSTFKLLLAARLLAGGD +---WRMAEALPVTAADMLDPAPVTRPRIGGTATLRELAAAMVTFSDNPAANIALRRSGGP +AALTRWLRGLGDDITRLDRMEPELNNETPGDPRDTTTPAAMLATTERLVLGDVLTPTARA +ELIGWMAASQTGATMLRPALPAGWTEAHKTGAGSDRARNIVSLITPPNRPPILVSAYLFA +RESSLEARNAPFPALGRAIVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Listeria sp. CLIP 2019/00642 TaxID=2705293 RepID=UPI0014314109 +--SVNEKLEVLENKYHAKLGVYATN--GNEKI-KYNAQERFAYTSTYKAIISGLLLKNRT +--EEELQKTILFSKEDLVDYSPITEKFVDKGMTLKEIIHAAVAYSDNTAGNLLFDEIGGT +KKFQKALRKIGDNTTIASRYETDLNSAVPGDLRDTTTPEAFGMDLQRLTDPEYLNPQALS +YFKQTLVDNTTGDKLIRAGVPEGYIVGDKTGAGSYGTRNDIAIIFKENSAPFVWTVFSKM +DQEDAQYNDQLIADVAKVLSEEf +>[subseq from] class A beta-lactamase n=1 Tax=Microbacterium halotolerans TaxID=246613 RepID=UPI000E6AA443 +---LDDDLESLEDEFQARVGVSVLDTGTGATI-EYRSDERFGYASTLKVFAVAEMLRQVA +--PEQRDEIVTWTDETVAQYSPVTAEHVADGLTLAQLAEAALRDSDNAATNLILDRIGGT +EGLQAGLELLGDTTTDVADIEPELNEVVPGETGNTTAPAAFASGLAAVLKPEHLDPADRT +TLLEWMSANATGDALIRAGAPADWVVADKSGGAG-GKRNDIAVVTPPGQSPIIVAILTEK +YDPDAAYEDELVARVAEAVL--- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A2A3Z0D2_9MICO +--EVDSAIADIEKKYDARVGVHAMDTSDGSTI-EHRSKERFGFASTIKSFAVAELLARTT +--PAELDEHVTWTKEDVEKYAPVTEKHLGDGLPLEKVAEAAIRVSDNAAANIVFDHIDGP +KGLDSALEDLGDSTTEVIDREPDLNTIDPGSADNTTTPAAFSNDLAALLEPEHLSDEDRT +VLIDWMSDNETGDPLIRAGAPAGWTVADKSGHAD-ALRNDVAVVFPPKRDPIVIAIMTEN +NDPNTESDAELIEDTAHAVLGAf +>[subseq from] Beta-lactamase n=2 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A3S8SMV1_9MICO +--EVDSAIADIEKKYDARVGVHAMDTSDGSTI-EHRSKERFGFASTIKSFAVAELLARTT +--PAELDEHVTWTKEDVEKYAPVTEKHLGDGLPLEKVAEAAIRVSDNAAANIVFDHIDGP +KGLDSALEDLGDSTTEVIDREPDLNTIDPGSADNTTTPAAFSNDLAALLEPEHLSDEDRT +VLIDWMSDNETGDPLIRAGAPAGWKVADKSGHAD-ALRNDVAVVFPPKRDPIVIAIMTEN +NDPNTESDAELIEDTAHAVLGAf +>[subseq from] class A beta-lactamase n=1 Tax=Zymomonas mobilis TaxID=542 RepID=UPI0001B705A0 +---------EYEQATGGHVGIYAQNIETGKSL-AWRANERFLMCSSFKVSLVASVLLRCD +RGQDSLDRIISYKPEDIEDYAPFAKAHLDKAMSVAELCQGAIEQSDNFCANKLLERSGGV +LALTAFWRQLGDNQSRLDNIEPFLNETPYGGIENTTTPIAMAHNLQKMLLGSLLSPSSRD +RLIGWMVRCQTGSQRLRAGLPKNWVIADKTGTNGHDAASDIAILWPRPDKAIILSVYVWG +GTPTKDQLLGLFSKIA------- +>[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium sp. YB235 TaxID=1496080 RepID=UPI001421FA83 +hqRLEDQLKKLEARYDARVGVSALDTESGESV-DHRADERFGFASSLKVFAVAELLDRTT +--PKELEKNVTWTQADVDEWTPVTEKHVDDGLPLEDVAESALRVSDNLAMNIVLDELGGP +EALDDAMEKDGDSTTEVTDEEPELNDVEEGSTDNTTTPAAFTANLQGLLDAKRLSDDDRK +VLFDWMSANETGDPLIRAGAPEGWVVRDKSGHSD-AIQNDIAMVTPPDRKPIIISVMTET +DDSESEDRPDLVAAVAEVVLDSf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00091220D7 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIESSMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF1E4BB +------------------------------------------------------------ +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLIEIGDTVTNPERFEPELNEVHPGEIHDTSTPKALATSLQAFALGDILSTEKRN +LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDAKYDDKLIAEATKIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Microbacteriaceae bacterium 13S1-3 TaxID=2144185 RepID=UPI000D371751 +--DVSAELTALEARYSARVGVSAMDTGTGREV-AFRAGERFAYASTLKVFVAAEFLRRVP +--AAERDAMVTWTRGDVDDYSPVTGARVAEGLPLAALAEAAVRSSDNAATNLLLDRLGGP +ASLDAGLEELGDTTSEVVHDEPALNRVSPGAVADTSTPLAFTANLRTLLLGDALAPADRQ +LLTEWMSGNATGDALVRAGAPEGWAVADKSGGAG-GIRNDVALVTPPGRDPILVTVFTEK +TDEGAAYEDRLVAETAAVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. 374 TaxID=1150400 RepID=A0A1H1APP6_9CAUL +-------LSDLEARNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRRIPITAADMINHAPVTEPAVGVSLTVEQLMKGAVEVSDNPAANLLLKAMGGP +SAMQTFYRGIGDDSTRSDRFEPEMNRL--DGDKDTILPNQSVANLQHLFLASALTAASRA +LLLQWMTDTPTGQNRLRAGTPANWRVAHKTGTGGYGPTNDIGLLYPPNGQPVIVAAYYHA +ARATSDDANAVIAEATRRAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Zymomonas mobilis TaxID=542 RepID=UPI00114F0D19 +---------EYEQATGGHVGIYAQNIATGKSL-AWRANERFLMCSSFKVSLVASVLLRCD +RGQDSLDRIISYKPEDIGDYAPFAKAHLDKAMSVAELCQGAIEQSDNFCANKLLERSGGA +LALTAFWRQLGDNQSRLDNIEPFLNEMPYGGVENTTTPIAMARNLQKMLLGSLLSPSSRD +RLIGWMVRCQTGSQRLRAGLPKNWVIADKTGTNGHDAASDIAILWPQPDKAIILSVYVWG +GTPTKDQLLSLFSKIAH------ +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1K591_9ZZZZ +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVADH---------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WVN0_9BACT +--SLQKQFEEIASVAAGPVGVAVLEIETGELV-TLSGKQHFPMQSVYKLPIGMAVLQQVD +KGLLKLDQIVHVKPADLVPGSPLRDRHPQGAVTLSELLSLMVKDSDGTASDVLLNLIGGP +DAATKYLRELGVEDIVVATSERDMAGDVQVQYRNWSTPEAMVGLLKLLHEGRGLTAASRT +LLLDWMVKTQTFPTRLKGMLPEGTIVAHKTGSSGARATNDVGLITLPNGHHLAIAVFVSD +TKADAKTRDAVIARSARAAWDCw +>[subseq from] class A beta-lactamase n=1 Tax=Plantibacter sp. M259 TaxID=2583822 RepID=UPI0011103BA9 +--DLSVEFQALEAEFGARVGISAVDTGTGARL-SYRVDERFGYASTIKALAAAVFLHEVR +--GSARDEVVTWSAEDVDAYSPVTSEQVETGLTLSQLAEAAVRRSDNTALNLVLARIGGP +AALDTALVTLGDEVTEVVNAEPQLNVIEPGSTDDTSTPAAFTDTLIRLVDGSYLESADRA +TLLAWMSGNATGDTLIRAGAPAGWQVADKSGGAG-GIRNDIAIIDRPSGDPIVLTILTNT +LDPDAEYDDALVAEAARVALAAf +>[subseq from] Beta-lactamase n=3 Tax=unclassified Curtobacterium TaxID=257496 RepID=A0A4R3U7U8_9MICO +--TVRRAIAGLEREYDATVGVVATDTVTGERV-AYNGDRRFGYASTIKAFAAAQFLRSVP +--ADARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP +SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALATVLDGSTLDRADTA +LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR +NDPDAAYDDALVARSASAVLDAf +>[subseq from] BETA-LACTAMASE n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0000112161 +-----KELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELMYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00132EF2F3 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQAP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. PhB137 TaxID=2485182 RepID=A0A3N4VV40_9MICO +--TVRRAIAGLEREYDATVGVVATDTVTGERV-AYNGDRRFGYASTIKAFAAAQFLRSVP +--ADARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP +SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALATVLDGSTLDRADTA +LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR +NDPDAAYDDALVARSASAVLDAf +>[subseq from] Beta-lactamase n=4 Tax=Staphylococcus TaxID=1279 RepID=D2J8J7_STAEP +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGN +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI000B516E26 +--ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKALSSAMLLEKTP +--HNKLNKKVHVSKEDIVPYSPVLEKFINKDISIKKLIEATMLYSDNTANNMIIEELGGY +KEVNKRLKSLDDKTTKPSRMEPELNNYNPKSNRDTSTPQAFGKTLNKLIKDGRLSKENKA +FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSETAKVVLEKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus capitis TaxID=29388 RepID=UPI000CD2B476 +----AKELNDLEKKYNTHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000458F496 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKSGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNIINKf +>[subseq from] Penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus warneri TaxID=1292 RepID=A0A658D631_STAWA +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASKNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Chitinophaga sp. S165 TaxID=2135462 RepID=A0A317LLA1_9BACT +-----NKVYEIAGAAQGHVGMAMLSLEDGDTM-TLNGNDRFPMQSVFKFPLAIAVLDQVD +KGKLALDEVIHIRKEDLMPWSPIRDKFPEGTMKLRDILAYTVSQSDNNGCDLLFRLVGGT +EYVNKYIHGLGIDSIAIKATEKQMGQAWDVQYTNWSSPVAMLGLLQKVYAGRYLSKTSND +FLLKVLRETTTCPNRMRGLLPKDAVVAHKTGTSGTAATNDVGIVTLPNGKHYAIAVFVSN +SKADEATRDAIVAQLTHLFWN-- +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI000D1BEAA8 +--ATTQDLKKVEDKYDANVGVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP +--HNELNKKVHISKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY +KEVNKRLKSLDDKTTKPSRMEPELNNYDPKSNKDTSTPKAFGKTLNKLINDGHLSKENKA +FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIILVIFTNK +EGKTDKPNDKVISETAKVVLEKf +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI000733F1E2 +--ATTQDLKKVEDKYDANIGVYALNTATDKEI-TFNEDKRFAYASTFKAVSSAMLLEKIP +--HNKLNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY +KEVNKRLKSLDDKTTKPSRMEPELNNYDPKNNRDTSTPQAFGKTLNKLINDGRLSKENKT +FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSETAKVVLEKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044DFEFB +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITFKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTHPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=2 Tax=Hapalosiphonaceae TaxID=1892263 RepID=A0A4D9CCD2_MASLA +--ELYNRIEEISRTAQGRVGVAVTMLETGESV-TLNGDQRFPMQSVYKFPIGMAVLAQVD +QGKLKLEQRIRVEKNDFVSHSPIRDDNPQGVLSLTQLLKYMVSESDGTACDVLLKLVGGP +EVVMKYLRDLGINGINVINTEKEIGQDKSVQYRNWATPEAMIVLLRALHEGRGLSKSSQG +LLLRLMTETPTGLGRIKGMLPDGTVVAHKTGTSRTAATNDVGLVTLSNRQHLAIAIFVSD +STAEDAAREEVIAKVARAAWDKw +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio sonorensis TaxID=1004316 RepID=UPI0008D8EA66 +-sELHQRLAEIESRVEGRIGIAFVDSATGFRW-SYRGNETFPVLSTFKPLACAKLLHDMD +SGQLNHDQSAYIKRDDIVEWSPVTKELTNSQISLISACEAALSMSDNTATNIVLNNIGGP +DALNQFLRKVGDKSTRLDDLEPFINQV--KERENTTTPVAMTNTMSHLFLGEGLSEGAQK +TILGWMERNRVSMALLRSVLPYGWSIADRSGSGSKGSRGITALIWKETRKPLVMSIYVTE +TNLTLSDRNQLIADIGEVIFS-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DA92618 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSKPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A2S6QBE8_9PROT +--TLVKSIKKIETDFDAKVGVAVYDLNTNDLW-SYNADETYPLMSTFKTLACANVLKQLD +EGKLSLDTEIKIDSSDIVTWSPVLKDKANQSLTIKQLCDAMMMQSDNSAANIILKTLGGP +ESITQFAKTLGQTKTNLTRNEPNLNNVTALDKIDSTTPNEMVRMLDSLLYTNILSEKSKL +QLLEWMKQNQVSDILLRSITPEDVNIADRSGANE-GGRAITAVVWNDKMKPIIIAIYIAH +SNLEQKYLHEAIVDIGEKIYRQf +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter sp. ANC 4105 TaxID=1217703 RepID=N9MGG5_9GAMM +---LEEQVKTL-SEKGWQIGVSILDMD-DKLI-SINGDKRFPLDSTVKALACANVLAKVD +AKKLSLDHSKTIQQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP +AGLTSFMRSIGDEVTRSDRYEPDLVINPEGDIRDTTSPNAMNASMKKLLMGNVLSKSSKE +QLKEWMIGNKVADNMLRASLPKGWKIADRTGASDYGIRGLTSMVWSESHAPVFISIYVRK +SETSLDQRSEVIKLLSDHIVKEy +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI000C313BF0 +----AKGLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI0001F48FFE +---HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATFASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000768EA1C +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDIALKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A411G5Q2_PROMI +-------------------------------------EERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITKSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRHDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRG------------------------ +----------------------- +>[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=UPI0013768B53 +--------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ +GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP +EGLTSFIRAHGDKITRLDRIEPDLNENIAGDPRDTTSPAAMAGLMGRLLFRDM-AAADAD +RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR +PTVDDKKAEAGIAEAAHSAL--- +>[subseq from] Beta-lactamase n=1 Tax=Ohtaekwangia koreensis TaxID=688867 RepID=A0A1T5MBZ8_9BACT +-kSLATAIDQVVRSIDAQTGVAILHIENRDTV-SVHGKAHFPMQSVFKFPLAMAVLHAVE +EGKFTLDQKIHVRKEDLLAWSPMAKKYPEGNVPLHELLMYTVSFSDNSTCDILFRLMGGV +KNVQKYIHDLGIKSIAIVATEEEMHREWSVQFTNWCEPVAMVQLLDILYKQKALSKDNTE +LLLKWMIETPTGAHRIKELLPAGTIVAHKTGTGGIGAINDVGIVTLPNGKHIAIAVYISR +TT-DEKKAEEAIAKIAKVAYDYy +>[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas diminuta TaxID=293 RepID=UPI000B358824 +------DLSALEARHGGRLGVSVAT--EGQSA-AWRGDERFVYCSTFKMYLAAATLLRIQ +AGRERLDRAIPVTQADMISHAPVTKPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL +DALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLILSESLESASKR +LLLEWMVASPTGQARIKAGVPAGWTVAHKTGTGGYGPVNDIGVLYPTDGAPIAIAVYFHA +TKSTDAQREAVIADATRQALK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1C5 TaxID=2080538 RepID=A0A2S5XFW0_9MICO +---VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPRRDAVVLSILSTR +NDPEADYDDALVARAAAVVL--- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Ohtaekwangia koreensis TaxID=688867 RepID=UPI0009A55D9B +-kSLATAIDQVVRSIDAQTGVAILHIENRDTV-SVHGKAHFPMQSVFKFPLAMAVLHAVE +EGKFTLDQKIHVRKEDLLAWSPMAKKYPEGNVPLHELLMYTVSFSDNSTCDILFRLMGGV +KNVQKYIHDLGIKSIAIVATEEEMHREWSVQFTNWCEPVAMVQLLDILYKQKALSKDNTE +LLLKWMIETPTGAHRIKELLPAGTIVAHKTGTGGIGAINDVGIVTLPNGKHIAIAVYISR +TT-DEKKAEEAIAKIAKVAYDYy +>[subseq from] Class A beta-lactamase n=2 Tax=Plantibacter flavus TaxID=150123 RepID=A0A4U3G0K4_9MICO +------EFQALEAEFGARVGVSAVDTGTGARL-SYRADERFGYESTIKALAAAVFLHEVR +--GSARDEVVTWSAEDVEAYSPVTSEQVETGLALSQLAEAAVRRSDNTALNLVLARIGGP +AALDAALVTLGDEVTEVVNAEPLLNVIEPGSTDDTTTPAAFADDLIRLVDGSYLEPADRA +TLLAWMSGNATGDTLIRAGAPAGWQVADKSGGAG-GIRNDIAIIDRPGGDPIVLTILTNT +LDPDAEYDDALVAEAARVALAAf +>[subseq from] Beta-lactamase n=5 Tax=Staphylococcus aureus TaxID=1280 RepID=D2JKK7_STAAU +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDIALKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKNLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000BA7BBDD +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYSKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Zymomonas mobilis subsp. mobilis NRRL B-12526 TaxID=1194424 RepID=A0A2R9NW34_ZYMMB +---------EYEQATGGHVGIYAQNIATGKSL-AWRANERFLMCSSFKVSLVASVLLRCD +RGQDSLDRIISYKPEDIGDYAPFAKAHLDKAMSVAELCQGAIEQSDNFCANKLLERSGGV +LALTAFWRQLGDNQSRLDNIEPFLNETPYGGIENTTTPIAMAHNLQKMLLGSLLSPSSRD +RLIGWMVRCQTGSQRLRAGLPKNWVIADKTGTNGHDAASDIAILWPQPDKAIILSVYVWG +GAPTKDQLLGLFSKIA------- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter sp. NIPH 2100 TaxID=1217708 RepID=N9RPS0_9GAMM +--TLEEQIKTL-SEKGWQIGVSILDM-NDKLI-SFNGDKRFPLDSTVKALACANVLAKVD +AKKLSLDHAKTIQQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP +AGLTSFMRSIGDKVTRSDRYEPDLVINPEDDIRDTTTPNAMNASMKKLLAGNVLSKSSKE +QLKEWMIGNKVADNMLRAALPQGWKIADRTGASDYGIRGLTSMVWSETHAPVFISIYVRK +SETSLDERSEVIKLLSDHIVK-- +>[subseq from] Beta-lactamase n=1 Tax=Bordetella holmesii CDC-H585-BH TaxID=1331206 RepID=A0A158M9I8_9BORD +------------------------------------------MCSTFKVLAVGAVLARVA +RGEDDLSRPMRLSAADIVAHSPVTQQRLNEGMTLGQLCDAALVVGDNTAANLLLSTIGGP +PGVTAYARSLGDAVTRLDRLETALNDATPGDDRDTTSPVAMAENLRQLVLGDALPGPERE +RVRDGLLHCQTGKGRLRAGLPAAWTFGHRTGAGGHGTCNDIGIAWPPSAGPVVISAYLTE +SPLPLPERERVLAEAGRIVVH-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A411G5R6_PROMI +-------------------------------------EERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRHDSWEPELNEAIPNDERDTTLPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRG------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY2B5 TaxID=2080570 RepID=UPI000CE786B3 +---VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Beta-lactamase n=2 Tax=Acinetobacter beijerinckii TaxID=262668 RepID=N9EC93_9GAMM +---------NLLQQKGWKVGVSIFDSNSKKLE-SVNGDTRFPLDSTVKALACANVLSNVD +KGLLSLENKVLIEEKDVVSHSPVTMKLINKSITLRDACAATTAYSDNTAANIAISSVGGP +QKLTQFMRELGDTKTRSDRYEPELVINPEFDLRDTTTTDAMSESLSKLLVGNTLSKKSRE +QLKSWMMDNKVADNMLRARLPNGWSIADRSGASDYGIRGITSMVWSKTQEPLFISIYVRK +SNTTLDERSRVINEIGEVIFNRy +>[subseq from] class A beta-lactamase n=1 Tax=Frigoribacterium sp. Leaf164 TaxID=1736282 RepID=UPI0009EAF10E +--ELDAALAALESEHGARVGLSVVDTGTGRAL-EHRGDERFLYASSLKALAAAALLDATE +--PADLDEVVTWTADDVAAYSPATSAATGTGLTLGQLAEAAVRQSDNTALNLVVEHLGGP +AALDAALAAQGDDVTDVVHGEPELNRPTAGSTADTTTPAAVRGLLARVVAGEWLGDDDRA +QLLEWMSGNATGDALVRAGAPEGWAVADKSGGAGP-VRNDVAVVTRPGGDPVVIAVLTTR +TDPAAAYDDALVAAAARAAFE-- +>[subseq from] class A beta-lactamase n=1 Tax=Acidisoma sp. S159 TaxID=1747225 RepID=UPI00131A92C3 +--DAADSIADVERRYGGRLGVFAVDTGSGRTL-AYRADERFLMCSTFKGLLAGLVLSRVD +AGKEELTRMVGYGEKDLIFTSPITKVNVSRGMSVEALCQAMLEVSDNTAAVLLMRSVGGP +PGLTRFLRGLGDLTTRSDRYEPASNEY--SGMLDTTSPRAIVGSAQKILLGEVLSPRSRD +QLEAGMIACKPGLKRIRSALPPDWIAGDRPGTSLGEETNDYAIVRPPGHAPILVAAYYDA +PKLSMDAREAVLRNAGSAFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1D2 TaxID=2080543 RepID=UPI000CE81CD9 +---VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEETTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSTR +NDPEADYDDALVARAAAVL---- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012ECE9B3 +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIETSMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI0014332A94 +--ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP +--HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY +KEVNKRLKSLDDKTTKPSRMEPELNNYDPKSNRDTSTPQAFGKTLNKLINDGRLSKENKA +FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSETAKVVLEKf +>[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=A0A6A2BTQ7_STAEP +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKSSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] class A beta-lactamase n=1 Tax=Frigoribacterium sp. Leaf263 TaxID=1736313 RepID=UPI0006FEF943 +--DASAELTALEAEFDARVGVSALDTGSGATL-VHRQEERFGYASTIKVFAAAAFLHDVP +--VDQRDEVVTWTAADVAAYTPVTSQYVDGGMSLVALAEAAVRTSDNLALNLVLDRIGGP +AGLDHALEQLGDTTTEVVADEPALNTIEPGSTDDTTTAAAFTADLAALATGDHLAAADRA +TLLDWMSGNATGDALIRAGAPDGWTVADKSGGAG-GMRNDVAVVTPPGRDPLVVTILTER +NDPDAAYDDVLVARVASVVLA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A649UIN6_ACIBA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEKRFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVKELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKV------------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas diminuta 3F5N TaxID=1255603 RepID=A0A1R4GS71_BREDI +------DLSALEARHGGRLGVSVAT--EGQSA-AWRGDERFVYCSTFKMYLAAATLLRIQ +AGRERLDRAIPVTQADMISHAPVTKPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL +DALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLILSESLESASKR +LLLEWMVASPTGQARIKAGVPAGWTVAHKTGTGGYGPVNDIGVLYPTDGAPIAIAVYFHA +TKSTDAQREAVIADATRQALK-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00066A6CEC +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGN +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI000D1F8C3D +--ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKALSSAMLLEKTP +--HNKLNKKVHVSKEDIVPYSPVLEKFINKDISIKKLIEATMLYSDNTANNMIIEELGGY +KEVNKRLKSLDDKTTKPSRMEPELNNYNPKNNRDTSTPQAFGKTLNKLINDGRLSKENKT +FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSETAKVVLEKf +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY2B9 TaxID=2080572 RepID=UPI000CE8C8BB +---VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR +NDPEADYDDALVARAAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Nesterenkonia halophila TaxID=302044 RepID=UPI0012912873 +------AVDQLEQEYDARVGVSMIDLDDGSTL-SHRGGERFGFASTMKAFAAAALLHSTG +--AEERGQLVRWTSADIEAYSPVTEQAVDTGLTLGELAEAAVRQSDNTAMNLIVEHLGGP +EGLQRALEGIGDSVTRPVDREPELNDVVAGETANTSTAEALAGNLERLVAGEWLDEDDRR +MVMDWMGGNATGDTLIRAGAPEGWSVAEKSGGAG-AMRHDVAVLQPPEGEPIVLVVLTER +NDADAEYEDALVADVAEAVL--- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus sp. MB371 TaxID=1663557 RepID=A0A1T1DCG3_9STAP +--ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKALSSAMLLEKTP +--HNKLNKKVHVSKEDIVPYSPVLEKFINKDISIKKLIEATMLYSDNTANNMIIEELGGY +KEVNKRLKSLDDKTTKPSRMEPELNNYNPKSNRDTSTPQAFGKTLNKLINDGRLSKENKT +FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSETAKVVLEKf +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI000E693F61 +--ATTQDLKKVEDKYDANIGVYALNTATDKEI-TFNEDKRFAYASTFKAVSSAMLLEKIP +--HNKLNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY +KEVNKRLKSLDDKTTKPSRMEPELNNYDPKNNRDTSTPQAFGKTLNKLINDGRLSKENKT +FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSKTAKVVLEKf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X795_9BACT +-eSLRKEIENLVRPVNGSIGVGVRHLESGDTL-TIHGKDHFPMQSVYKFHLALAVLSDVD +QGKLSMDQKVLIRKEEFIPVSPIADKYPDGNLTVSELLSYTVSNSDNNGCDILFKLVGGP +KKVEAYIRGLGVRDVAIVNTEREMHQDWDAQFNNWTTPQGMVQLLDLFYQKKILSPESRD +FLVKIMEQAATGKKRIKGQLPAGTVVAHKTGMGGNDAMNDVGVVTLPSGGHFAIALFVTN +PKDSIEVVEAVMAKISKLVLDHy +>[subseq from] Beta-lactamase n=10 Tax=Staphylococcus TaxID=1279 RepID=A0A1D4EG02_STAAU +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDIALKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGIPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI00107230B1 +--ATTQDLKKVEDKYDANIGVYALNTETDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP +--HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNIIIEELGGY +KEVNKRLKSLDDKTTKPSRMEPELNNYDPKSNRDTSTPQAFGKTLNKLINDGRLSKENKA +FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSETAKVVLEKf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TCM1 TaxID=453246 RepID=A0A196MVB3_9SPHN +--------AEIEKETGGRLGVALVD-RSGALLlGFNRDERFALCSTFKGPLAAAVLLGAE +AGKFGLEGEISFGKDDILDYAPVVKKNRKRGMSMGELAQAAVEVSDNSAANLLLPMLGGP +PGLTAFMRAHGDRVTRLDRNEPALNENAEGDERDTTSPAAMAGLMGRLFFRDM-KPESAD +RLRAWFNASSTGDHRIKAGLPEGWTSGSKTGTCGT-AYNDVALVKSAAGDEYILAIYLDR +PTVDAGKAEAAIAETARAALD-- +>[subseq from] class A beta-lactamase n=1 Tax=Frigoribacterium endophyticum TaxID=1522176 RepID=UPI00141DFE2C +--ELDAALAALESEHGARVGLSVVDTGTGRAL-EHRGDERFLYASSLKALAAAALLDATE +--PADLDEVVTWTAGDVTAYSPATSAATGTGLTLGQLAEAAVRQSDNTALNLVVEHLGGP +AALDAALAAQGDDVTDVVHGEPELNRPTAGSTADTTTPAAVRGLLARVVAGEWLGDDDRA +QLLDWMTGNATGDALVRAGAPEGWAVADKSGGAGP-VRNDVAVVTRPGGDPVVIAVLTTR +TDPAAAYDDALVAAAARAAFE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1E8 TaxID=2080555 RepID=UPI000CE89263 +---VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLETLGDTTTEVVNEEPALNTIEPGSTDDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR +NDPEADYDDALVARAAAVVL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI001290BD16 +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYSSTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q5MDG4_ECOLX +--ETLVKVKDAEDQLGARVCYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLR------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Taibaiella soli TaxID=1649169 RepID=A0A2W2A739_9BACT +-eDLKQNIQKITAGKKAEVGISIRGIENGKTV-SINGNKHYPMQSVFKFPIALTVLHQVD +AGKLKLEQLITIKRSELLQWSPLREKYPKGDIPLSEIIQYTVSQSDNNGCDVLLRLIGGP +AVVNDYIHSLGVKDIAIKANEEAMHKDWNVQFTNWCAPDAMTALLIKFYQQKILQPTTHA +FLWKTMAETTTGKNRIRKLLPAGTIVADKTGSSGTAALNDVGVVTLPNSQHFAITIFVSD +SKENNDTNEQIIADIAKAAWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas phyllosphaerae TaxID=257003 RepID=UPI0004244673 +--SVERALAALERRAGGRLGVSIVDTGRGTTI-GWRAHERFTQASSFKLSLAALILAEAD +RGRLVLTERLGWSAGDILPHSPVTTASAAMTLPIRELARAAVVTSDNTAANVLLRKIGGP +ARLTAFWRAGGDRVSRLDRYEPALNVTPPGTTLDTTTPAAMAATVARLVRGPVLRPASRA +LLTEWMVAANTGRHRLRAGFPADWYAGDKTGTGGRPIFVDLAFACPRGRAPLIVAAYFEP +VRASSESAEAVLAKVGRIAAGSf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0005DDB270 +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELEDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000CE8A922 +---VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPRRDAVVLSILSTR +NDPEADYDDALVARAAAVVL--- +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI000BBE33F6 +--ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP +--HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNIIIEELGGY +KEVNKRLKSLDDKTTKPSRMEPELNNYDPKSNRDTSTPQAFGKTLNKLINDGRLSKENKA +FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSETAKVVLEKf +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI00132FD48C +--ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP +--HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNIIIEELGGY +KEVNKRLKSLDDKTTKPSRMEPELNNYDPKSNRDTSTPQAFGKTLNKLINDGRLSKENKA +FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSETAKVVLEKf +>[subseq from] BETA-LACTAMASE n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0000110FF8 +-----KELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSHAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. Leaf20 TaxID=1735685 RepID=A0A0Q4G3U2_9SPHN +---ASDPIAEYERATGGRIGVFAINVKTGAKL-SWRADERFITCSSYKASLAAFVLSRVD +RGEERLDALVPYTVKDTLDWGPVSKANLAKGMTVEAMCKAAVEISDGVCANLLMARSGGP +LALTAFLRSIGDRATRIDHYEPQLDRVPSGGPEDSTTPAMMASTLQKAVLGKVLSDQSKA +LLTRWLVGNQT-NPRLRGGLPTSWRIGNKTGHSGRDMAGDIAVAWPRPDTPIVIAVYTRG +GRPTEKQFDQAFAGVGRLVAS-- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1D1 TaxID=2080542 RepID=UPI000CE8114F +---VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPRRDAVVLSILSTR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. GW460-12-10-14-LB2 TaxID=1827469 RepID=A0A160HZH1_9CAUL +-------LADLEARNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKIYLAAATLLRAQ +AGQERLDRRIPITAADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP +SAMQTFYRGIGDGSTRSDRFEPEMNRL--DGDKDTILPNQSIANLQRLFLDPALTAASRA +LLLQWMTDTPTGQNRLRAGAPANWRVAHKTGTGGYGPTNDIGLLYPPNGQPVIVAAYYHA +TRATSDDANAVVAEATRRAL--- +>[subseq from] Beta-lactamase n=1 Tax=Chlorogloea sp. CCALA 695 TaxID=2107693 RepID=A0A2T1E3G7_9CHRO +-nELHDRIEQTSRAAQGRVGMTATVLETGESV-SLNGNQRFPMRSVYKFPIAMAVLAQVD +QGKLKLDRQIRVEASDIVQGSRILDRNSGVELSLTELLKYMVSESDNTACDVLLRLVGGS +KIVTQYLRGLSVNDIIVANTEKELGQDTAVQYRNYATPDAIVVLLRTFHEGQGLSKSSQA +LLRRLMTETSTGLNRIKGLLPEGTVVAHKTGTSSTAATNDVGLVTLPNSRHLAISVFVSD +SMADDTTREEVIAKVARAAWDEw +>[subseq from] Beta-lactamase n=1 Tax=Celeribacter baekdonensis B30 TaxID=1208323 RepID=K2K1M7_9RHOB +----DSYMDRMERELSARIGVYVKNLGTGQAY-QRRAGERFAMCSTFKASLAALCLWRSD +HGELDLNEALAFNGMSFLPTSPVTKDHASAGMDIRSLCKAAVEFSDNTAANLLLARVGGP +KAVTAFFREMGDDISRLDRIELALNSNIPGDERDTTTPLAMAHNLQQMTMSGVLSVASTD +LLTKWMRNEQNAKNRIRAAVSSDWVVANKPGTTPNGAANDIAALWSPGGDALVMAIYIDT +EKGNTRAAVAAIRDISASA---- +>[subseq from] Beta-lactamase n=1 Tax=Plantibacter flavus TaxID=150123 RepID=A0A3N2BXV6_9MICO +--DLSVEFQAVEAEFSARVGISAVDTGTGARL-SYRADERFGYASTIKALAAAVFLHEVR +--GSARDEVVTWSAEDVEAYSPVTSEQVETGLTLSQLAEAAVRRSDNTALNLVLARIGGP +TALDAALVALGDEVTEVVNAEPLLNVIEPGSTDDTTTPAAFADDLIRLVDGSYLEPADRT +ALLAWMGGNATGDTLIRAGAPAGWQVADKSGGAG-GIRNDIAIIDRPGGDPIVLTILTNT +LDPDAEYDDALVAEAASVALAAf +>[subseq from] Beta-lactamase n=2 Tax=Neoasaia chiangmaiensis TaxID=320497 RepID=A0A1U9KS83_9PROT +------PMATIERRHGGRLGVYVRDLASGRHI-AQRADERFMLCSTFKAILAAMVLDRVD +HGQDTLAAMLPYRAADLRPASPVTTAHLREGLPIGALCHAIMAFSDNAAANILLAHCGGP +PALTDFVRRVRDSTTRFDRYETESGH--RDGDKDTTTPHAMTHTLETLLWGPTLQPSSRI +QLADWMQGNQVGARRLRAGFPPDWTVGDRTGTGD-GFCNDCAFAHLPDGRTIMATVYYDA +PGMTTAAQEAVLREVAVAIA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1E4 TaxID=2080552 RepID=UPI000CE81225 +---VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWNVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPRRDAVVLSILSTR +NDPEADYDDALVARAAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY2B3 TaxID=2080569 RepID=UPI000CE73440 +---VSAELAALESEFDARIGVSAVDTGSGRRV-EHRSNERFGYASSLKALAVAEFLRTVP +--AAERDEVVTWTAADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRIGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGEVLSAEDRA +LLLDWMSGNATGDALVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILTAR +NDPEADYDDALVARAAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodobacteraceae TaxID=31989 RepID=UPI00125F4628 +----DSYMDRMERELSARIGVYVKNLGTGQAY-QRRAGERFAMCSTFKASLAALCLWRSD +HGELDLNEALAFNGMSFLPTSPVTKDHASAGMDIRSLCKAAVEFSDNTAANLLLARVGGP +KAVTAFFREMGDDISRLDRIELALNSNIPGDERDTTTPLAMAHNLQQMTMSGVLSVASTD +LLTKWMRNEQNAKNRIRAAVSSDWVVANKPGTTPNGAANDIAALWSPGGDALVMAIYIDT +EKGNTRAAVAAIRDISASA---- +>[subseq from] Beta-lactamase n=1 Tax=Cryobacterium sp. TMT1-51 TaxID=1259239 RepID=A0A4Y8JS35_9MICO +-sALQTALGELEDQYDARIGLSVTDTADGSTL-NYQGDSRFGYASTLKTLAAAALLDRTT +--PEQLDRVITWSEADVLEYSPVTSEHIDTGLPLGDVAMAAMRASDNTAMNLMLKQFGGT +AGLDKILEDYGDNLTDVVDNEPGLNTVTTDNAANTSTPRAFTKTLERIMSGEILDDADRS +TLIDWMTGNATGDTLIRAGVPEGWEVADKSGGAG-AIRNDVAVVIPPDGIPVIITVFTTR +NNPDAKYDDALVAETARLAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C79C079 +-------------------------------------------MSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIAV----- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A2W4QI94_9PROT +------DLAALEATHGGRIGVCAMS--EGGIV-KWRAGERFPYCSTFKLFLAASVMERVQ +DGLEKLDRAVPIAESDMVPHAPVTGPAVGSSLTIMQLLKATVEVSDNPAANILFREMGGL +EVFQKWYRSIGDRITRVDRNEVALNSALPGDHRDTTTPQQCVANLHSVLRRSLLSAGHLE +MLEKWLTETPTGTLRIKAAVPANYKVGHKTGTGAQNTRNDIGIIWPPRGAPILIAVFFTG +ARNAAEELDAIVAGSARAALQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Stakelama pacifica TaxID=517720 RepID=A0A4R6FF27_9SPHN +-------FDKLENAVNGKLYLAVLDTGTGHRL-TWNADQRVGLCSTFKLPLAAAVMAGAE +KGTLSLDTPVSISAADLLDYAPAVKANLAKGMTIGELARAAVTVSDNSAANLLLPQVGGP +RGLTRYLREAGDTVTSIDHPEPLINRVRPGQDADSTTPWAMAGLVNDLLFSQLLTEAHRR +TLAQWMIDSETGLKRIRAGLPVNWKAGDKTGTSGDGWYNDVAVAWPGEGRPIVIASYLWA +PDGQPDAADAVHAKIGELVG--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis lucentensis TaxID=53441 RepID=UPI0003744E84 +--EHAERFAALEERYDARLGVFAVDTGTGETL-AHNADDRFAYASTHKAFSAAAVLRRSS +--DEDLERVVTYAEEDLQEYAPIAKENLDTGMTLLEVCDAAVRYSDNTAANLLFDELGGP +SGLQEELREVGDDVTHVDRIEPGLNEAAPGDIRDTSTPRAMATTLRAYALGDVLPEERRE +VLVDMLRRNVTGDTVIRAGVPDDWTVGDKTGTAGYG------------------------ +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinomadura viridilutea TaxID=58112 RepID=A0A2P6ULD6_9ACTN +--EVTRRLRELEASYHGRIGAFAIDTGTGRTV-GHRTHERFPSNSTFKAVLCGAILHKAR +TADPGLMERRHYTAEEAKKHAPVTSENIENGLTTAELCHATITVSDNGAANVLLKQIGGP +KGLTRYYRSLGDPVGRLDTYEPELNEWEPGQKSNTIMPAFMARDLAKLTTGDALVPEDRR +QLNEWLKATTTGGTRIRAGLPDDWTVGNKTGTGGYATASDIAVAWRPSGAPLIFAVYTHR +DGRHPEIDDGVIAQTASILA--- +>[subseq from] Beta-lactamase n=1 Tax=alpha proteobacterium AAP81b TaxID=1523432 RepID=A0A0N1LGQ1_9PROT +--DLAATIATIEAR-SGRFGVAARDLASGWRF-AHRGDERFALASTFKLLLAGAILTAVD +AGRLRLAQTLHVTASDLVSYAPVTETLVGRRASLATLCDAAVTLSDNAAANLLLPLVGGP +AGLTRWLRRLGDPVTRLDRFEPALNLVPPGEVRDTTTPDAMLASVIRL--RDRLSAASRA +RLDAWLIASRTGGRRLRAGLPATWIVGDKTGTAS-GIANDVAIAWRPGVRPLLIAAYRAD +GG-DGAMADADHTTLARA----- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00119E5B96 +------------------------------------------------------------ +------GRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia brevicatena TaxID=37327 RepID=UPI0009FEADAB +------TLAELEDRHSVRLGVHAVDPRRELAY-IRRADERFALCSTFKVYAVAALLRQEQ +QGRLSLNDRVRIEPDEVVENSPVTEPAQGRAVALTELCEAALTRGDNTAANLILGRLGGP +RAITEFARTLGDNATVLNRWEPALNSAERGDLRDTTTPAGLGIGYRELLLGAALTPARQR +ILTDWMLANITSGERIRKGLPDGWTSADKTGAGSYGTVNDAGVVRSPNGDPLLLILLSDS +TTSDAPNNNVPLAEATTAIVT-- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia flavorosea TaxID=53429 RepID=UPI0009FFDD8B +--DLSNTLMEIQERHDVLFGIAAYSPTGARTF-EWNATDRFALTSTFKVYAVAALLRLAE +RGEVDLNEQVPILRSDIVIASPTTSYRAGETLSWYDLCQATLVRNDNTAANLILRRIGGP +PAVTALARTLGDTQTRLDRWEPALNEALPGDTRDTSTPAAFAGGLHRLVLGNALIPEHRR +MLTGWMRSSVTSGERMREGLPVGWVAADKSGTGAYGTVNDAGVVWSPTGTSVVLVIFSRS +TIPMAAPSDQAIADATTAVLE-- +>[subseq from] BETA-LACTAMASE n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0000111911 +-----KELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYDIELQYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=3 Tax=Brevundimonas TaxID=41275 RepID=A0A246K7L6_BREDI +-----LDLSALEARHGGRLGVSVAT--EGRSA-AWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRAIPVTQADMISHAPVTQPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL +EALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLLVDTPLSPASKT +LLMRWLVDTPTGQGRIKAGVPAGWTVAHKTGTGGYGPVNDIGLILPPNAAPIAIAIYFRA +TKSTDAQREAVIADATRQALK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1F9 TaxID=2080563 RepID=UPI000CE85479 +---VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEETTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR +NDTEADYDDALVARAAAVVL--- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. MYb31 TaxID=1848616 RepID=A0A2S8W5H1_9CAUL +------DLSDLEARHGGRLGLAVAS--GGVNA-AWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRAVAITAADMINHAPTTEKAVGSTLTVEQLMQATVELSDNPAANILIREMGGL +ETLRAFYRGIGDDSTRVDRLEPEMNRA--DGDKDTITPIQSVQNISRLLVDTPLNAASKA +LLMRWMTQTPTGQGRIKAGVPAGWTVAHKTGTGGYGPTNDIGLIQPPTGAPVVIAVYFHA +TRESDAQREAVIADATRLAL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00138AFB6E +---HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTSAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVISKf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A2L0W0L8_9BACT +---LKEKIARIVAPMKAEVGVSVLGIEDGKAL-SVNGENKFPMQSVFKFPIALAVLSEVD +KGRFALDQEMDIGKSDLLPWSPIREKYPDGNMSLAEVLKYTVSQSDNNGCDILLGLIGGP +EVVNDYIHGLGIKDFSVQFNEQEMHQDWNIQFSNWATPVAVTELLRIFYERKNMSLKSFD +FLWGVMMETKTGPNRIKGQLPPGTPVAHKTGTSDTAAVNDVGIITLPDGKHVAIAVFVAN +SREDSATNEKIIADISRAVWDDf +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A2E1YXE4_SPHSX +-------FDKLENAVNGKLYLAVLDTGTGHRL-TWNADQRVGLCSTFKLPLAAAVMAGAE +KGTLSLDAPVSISAADLLDYAPAVKANLAKGMTIGELARAAVTVSDNSAANLLLPQVGGP +RGLTRYLREAGDTVTSIDHPEPLINRVRPGQDADSTTPWAMAGLVNDLLFSQLLTEAHRR +TLAQWMIDSETGLKRIRAGLPVNWKAGDKTGTSGDGWYNDVAVAWPGEGRPIVIASYLWA +PEGQPDAADAVHAKIGELVG--- +>[subseq from] class A beta-lactamase n=1 Tax=Zymomonas mobilis TaxID=542 RepID=UPI000B399C7E +---------EYEQATGGHVGIYAQNIATGKSL-AWRANERFLMCSSFKVSLVASVLLRCD +RGQDSLDRIISYKPEDIGDYAPFAKAHLDKAMSVAELCQGAIEQSDNFCANKLLERSGGA +LALTAFWRQLGDNQSRLDNIEPFLNETPYGGVENTTTPIAMAHNLQKMLLGSLLSSSSRD +RLIGWMVRCQTGSQRLRAGLPKNWVIADKTGTNGHDAASDIAILWPQPNKAIILSVYVWG +GAPTKDQLLGLFSKIA------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=D2XSF4_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAEXXXXXXXXXXXXXXXXXXXXXXXX +XXVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILV----- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas vancanneytii TaxID=1325724 RepID=A0A4P1KA76_9CAUL +-----LDLSALEARHGGRLGVSAAT--EGRSA-AWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRAIPVTQADMISHAPVTEPAVGSTLTIEQLMQATVEVSDNPAANILIRELGGL +DALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTVTPDQSVRNIQRLLVDTPLSPASKT +LLMRWLVDTPTGQGRIKAGVPAGWTVAHKTGTGAYGPVNDIGLILPPNAAAIAIAVYFHA +TKSTDAQREAVIADATRQALK-- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter gyllenbergii TaxID=134534 RepID=A0A1B8UG29_9GAMM +--TLEEQIKTL-SEKGWQIGVSILDMD-DKLI-SINGDKRFPLDSTVKALACANVLAKVD +AKKLTLDHSKTIQQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP +VGLTSFMRSIGDEVTRSDRYEPDLVINPEDDIRDTTTPNAMNASMKKLLTGNVLSKSSKE +QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGLTSMVWSETHAPVFISIYVRK +SETSLDERSEVIKLLSDHIVK-- +>[subseq from] PROTEIN (BETA-LACTAMASE) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0000112163 +-----KELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYQIELDYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Dyadobacter flavalbus TaxID=2579942 RepID=A0A5M8QGE7_9BACT +-dELKAKIDSISKLVQGTVGIGIMDLKSGETL-YLNEKHQFPMQSVFKFPLGMAVLDQVD +KGKLSLDQKIHVKKEDLNPWSPLQKKFPEGNLSLRELLTYTVSLSDNNTCDILFRLVGGP +RNVNKYMQSIGVKGINIVATEAEMAKNWDVQFTNWCRPPAMIQLLDVFHQGKKLSKSSTE +FLMKIMTETPTGLNRIKGLLPENTKVAHKTGSSGTNAFNDAGIVTMPNGKSIAIVAFVSN +TPADEKTRDMVIAQISRAAWDYy +>[subseq from] Class A beta-lactamase n=1 Tax=Micromonospora inaquosa TaxID=2203716 RepID=A0A3N9X047_9ACTN +-----------------------------------------AYASTWKALAAAEVLDGAT +--DAQLDRVVRYSARDLVTHSPITEKHVGEGMSLRALADAAVRHSDNTAGNLLLRHLGGP +AGFESKLRALGDTVTDAARHETALNEGTPGDRRDTSTARALAGDLRAYTVGVALEPADRD +VLRGWLRGNTTGATLVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSTR +GKKDATPDDALTAQATRVVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=A0A2T4RV07_STASC +--ATTQDLKKVEDKYDANIGVYALNTATDKEI-TFNEDKRFAYASTFKAISSAMLLENTP +--HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIDELGGY +KEVNKRLKSLDDKTTKPSRMEPELNNYDPKNNRDTSTPQAFGKTLNKLINDGHLSKENKT +FLIDLMVHNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSETAKVVLEKf +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1H2 TaxID=2080566 RepID=UPI000CE8E855 +---VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEATVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRSGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter sp. NIPH 1867 TaxID=1217702 RepID=N9R0C2_9GAMM +--TLEEQIKTL-SDKGWQIGVSILDMD-DKLI-SINGDKRFPLDSTVKALACANVLAKVD +AKKLSLDHSKTIRQKDLVTYSPVVKEYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP +VGLTSFMRSIGDEVTRSDRYEPELVINPEGDIRDTTSPNAMNASMKKLLMGNVLSKSSKA +QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGLTSMVWSESHAPVFISIYVRK +SETSLDERSEVIKLLSDHIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000CE75369 +---VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIEDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRSGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR +NDPEADYDDALVARAAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1F6 TaxID=2080560 RepID=UPI000CE7B5FD +---VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEETTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSTR +NDPEADYDVALVARAAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. PhB172 TaxID=2485196 RepID=UPI000F4B7B79 +--AVRRALAGLEREYDATVGVVATDTVTGATV-AYNGDRRFGYASTIKAFAAAQFLRSVP +--ADARNEVVHWTAADVAAYSPVTEQHVAEGLSYGQLAEAAVRMSDNTALNLVLTRIGGP +SGLDTALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALATVLDGSTLDRADTA +LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR +NDPDAAYDDALVARSASAVLDAf +>[subseq from] Beta-lactamase n=2 Tax=unclassified Curtobacterium TaxID=257496 RepID=A0A4R1SDF8_9MICO +--AVRRALAGLEREYDATVGVVATDTVTGETV-AYNGDRRFGYASTIKALAAAQFLRSVP +--VDARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP +SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALATVLDGSTLDRADTA +LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR +NDPDAAYDDALVARSASAVLGAf +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. PhB78 TaxID=2485102 RepID=A0A3N2GID1_9MICO +--TVRRALAGLEREYDATVGVVATDTVTGETV-AYNSDRRFGYASTIKAFAAAQFLRSVP +--ADARNEVVRWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP +SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALTTVLDGSTLDRADTA +LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR +NDPDAAYDDALVARSASAVLDAf +>[subseq from] class A beta-lactamase n=1 Tax=Blastomonas sp. AAP53 TaxID=1248760 RepID=UPI0002ECCBE1 +--TIRADLAAIEARSGGRLGVALVDQ-DGRQVaGHRADERFALCSTFKLPLAAMVLEKAA +EGRWAMGDALPVTDADMVAYAPYVEAQRDKSVTVEGAAAAAVSLSDNAAANLLLDRLDGP +QGFTAWLRGKGDAVTRLDRREPKLNENAIGDLRDTTSPLAMAETTRRLVIGDAMPLGQQR +LLYRWMEDTATGLKRIRAGLPQGWSAGDKTGSCGN-AFNDVAVFTTAKGRRYALAVYLDR +PVVKGDDASAILADATRAL---- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. TNDT3 TaxID=2249354 RepID=UPI000E3C1CF2 +----ADEFADLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYCSTHKAFSAALVLQRNT +--PEEMEEVVTYDADDVFGHSPVTEQHVDTGLPLMEVADAAVRYSDNTAANLLFGELGGP +DGFEGAMEEMGDDVIEADRVEPGLSRWAPGDTRDTSTPRAMAGSLREFVLGDALPEDRRE +VLTRMLVDNLTGDELIRAGVPEGWEVGDKTGSGNYGTRNDIAVIWP-------------- +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Staphylococcus TaxID=1279 RepID=A0A0U2CIP0_STAEP +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGN +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPPAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=2 Tax=Inhella crocodyli TaxID=2499851 RepID=A0A437LH10_9BURK +----PPSLAALERRHGGRLGVAVLDTGSQRLW-GHREDERFGLCSTFKLLLAAAVLQQID +AGRLAADRWVPFHGAPKVPNSPVTDAHQAAGMTLLALAQATQTTSDNLAANLLMRELSGP +QWLTQWLRERGDAVTRIDRWEPEMNHVPPGEVRDTSSPAAMARTAALLLTGPVLQPPHRE +LLQGWTEATRTGLKRLRAGFSEGWRAGDKTGTGWADKINDVAIVWPPGRAPWVVAAYYEA +PRHTRPQDIAVLAAVGREVT--- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingosinicella sp. YJ22 TaxID=1104780 RepID=UPI001408E949 +--QADSRLADIERRTGGRLGVALLD-GRGRTVlGHRTGERFAMCSTFKFQLAAMMLDGAD +DGRWRMEDVLPLTPADTVRHAPVAERLLPTGITLAQAAAASQIQSDNATANLLLRRVGGP +AAFTAWLRGIGDSETRLDRYELELNENRPGDPRDTTTPTAYGETMRRLIFGDVLGGPSRE +QLRAWTSATTTGQRRVRGALPAEWPAGDKTGTCGT-AFNDIAWFRSPDGAEWVLAAFLDR +PIVPAAQAEAALAEVTAIALE-- +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI000D1E03AB +--ATTQDLKKVEDKYDANVGVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP +--HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY +KEVNKRLKSLDDKTTKPSRMEPELNNYDPKSNKDTSTPKAFGKTLNKLINNGHLSKENKT +FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSETAKVVLEKf +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. PhB151 TaxID=2485189 RepID=UPI00106350C4 +---VSAELAALEAEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKALAAAEFLRSVP +--ADERDEVVTWTAADVEAYSPVTGESIDGGLPLAQLAEAAVRRSDNTALNLVLDRLGGP +VALDRALEQLGDTTTDVVDDEPALNTIASGSTANTTTPAAFTADLTAVALGDALPAADRA +LLLDWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDAAVVTPPGRDPIVLSVLTSR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium baderi TaxID=1332080 RepID=A0A0S3F4M7_9SPHN +--------KMIEEETGGRLGVALVDSSGALIL-GFNRDDRFAMCSTFKAPLAAAILLGAE +GGKFGLEGQVSLTKDDLLSHAPVVKQNLKRGLSMEELAAAAVEVSDNSAANLLLPMIGGP +EGLTAFFRAHGDSLSRLDRKEPDLNENEAGDPRDTTSPAAMAGLMARLLFKDM-KPESAE +KLRSWLDQSKTGDHRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPTGAEYLLAIYLDR +PTVDEAKAEAAIAETAASALD-- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCJR17_020 TaxID=2175619 RepID=A0A2W1U324_9MICO +--TVRRALAGLERQYDATVGVVATDTVTGETV-AYNGDRRFGYASTIKAFAAAQFLRSVP +--ADARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP +SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALATVLDGRTLDRADTA +LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR +NDPDAAYDDALVARSASVALGAf +>[subseq from] Beta-lactamase n=1 Tax=Brevibacterium sp. 239c TaxID=1965356 RepID=A0A2H1KXU2_9MICO +-qKVSGELESLEEDFKARIGVSAVDTGNGTSF-DYRSDERFGFASTLKVFAVAELLARTT +--SADLDEQVTWTQADVDEWTPVTEKHVDTGLPLRDVAESALRVSDNAAMNIVLDEIGGP +QELDAALEDAGDPTTEVIDEEPELNDVDPDSSDNTTTPKAYTADLQGLLDPDRLPEDDRE +VLLEWMSDNETGDPLIRAGAPKGWTVKDKSGHSD-GIQNDIAVVYPPNEDPIIITVLTQS +EDPDSEDGPALVAAAAEAVFDSf +>[subseq from] Beta-lactamase n=2 Tax=unclassified Xanthomonadaceae TaxID=191676 RepID=A0A2M9ENL0_9GAMM +--DAEQQLLDLQQTSAGRLGVYVLDSETGRHL-ALRADERFGMNSTFKLLLAAVVLRAMG +EGEFAAEMTLPFSADDLVPHAPVIQARLDNGMHMIELAKAAQLTSDNTAANLLIRQLGGP +EGVTARWRALGDQVSRLDRYETEMNFVPAGEVRDTTTPRAMAETVARLFVGDVLGDGARE +DLKGWMLATETGLKRLRAGFPPGWQIGDKTGSGFEGKTHDVAVIWREGRKPVVIAAYYEA +DAGVRDEDEAVLAGVGRIVQ--- +>[subseq from] Beta-lactamase n=1 Tax=Polyangium fumosum TaxID=889272 RepID=A0A4U1JHR3_9DELT +--RLERDVAAAETRAGGRLGVAVVEPSSGQRW-VHHAGERFPLQSTFKAPLAAAVLARVD +AGALSLDTKIEVRRDELSVWSPLAEAFQGETFSVLDLLTQSVAVSDNTAADVLMHEIGGP +ESVNAMLARSGVTALHVDRYERDLQLAYLRDPRDTTTPEAAADFLLKLDRGEMLTPASTR +VLLDIMHGTKTGPRRLRAGLPPDARLAHKTGSSDNGATNDIGIATLPDGRKLVIVALLTE +SSAPQETREAALADVARAAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Acinetobacter dispersus TaxID=70348 RepID=UPI00132E8822 +---LEEQVKTL-SEKGWQIGVSILDMD-DKLI-SINGDKRFPLDSTVKALACANVLAKVD +AKKLSLDHSKTIQQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP +AGLTSFMRSIGDEVTRSDRYEPDLVINPEGDMQDTTSPNAMNASMKKLLMGNVLSKSSKA +QLKDWMIGNKVADNMLRAVLPKGWKIADRTGASDYGIRGLTSMVWSESHAPVFISIYVRK +SETSLDERSEVIKLLSDHIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Acinetobacter sp. TUM15071 TaxID=2609135 RepID=UPI00124D01BC +---LEEQVKTL-SEKGWQIGVSILDMD-DKLI-SINGDKRFPLDSTVKALACANVLAKVD +AKKLSLDHSKTIQQKDLITYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP +AGLTSFMRSIGDEVTRSDRYEPDLVINPEGDMRDTTSPNAMNASMKKLLMGNVLSKSSKA +QLKDWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGLTSMVWSESHAPVFISIYVRK +SETSLDERSEVIKLLSDHIVK-- +>[subseq from] Beta-lactamase n=2 Tax=Caballeronia sordidicola TaxID=196367 RepID=A0A2C9XW84_9BURK +--AAESPLADIERRRGGRLGVFAIDTGSGRTL-SHRADERFLMCSTFKGLLAAQILARVD +SGAERLDRVVRYTKKDLIFTSPVTKANVARGLSIDALYRAILVESDNTAAILLMRSAGGP +AALTRFVRSFGDTVTRSDRYEPDSNRY--HSVLDTTTPKTIATTAQRLLLGDVLSAGSRA +KLERGMTDCKPGLNRIRAVLPVGWQAADRPGTSVESETNDYALVRPPGRAPLLVAVYYEA +PGVGMDAREAVLREAGTAFV--- +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI0008076F53 +--ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP +--HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY +KEVNKRLKSLDDKTTKPSRMEPELNIYDPKSNRDTSTPQAFGKTLNKLINDGRLSKENKA +FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSETAKVVLEKf +>[subseq from] Beta-lactamase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A3S8SXP4_9MICO +--EVDSAIADIEKKYDARVGVHAMDTSDGSTI-EHRSKERFGFASTIKSLAVAELLARTT +--PAELDEHVTWTKEDVEKYAPVTEKHLGDGLPLEKVAEAAIRVSDNAAANIVFDHIDGP +KGLDSALEDLGDSTTEVIDREPDLNTIGPGSADNTTTPAAFSNDLAALLEPEHLSDEDRT +VLIDWMSDNETGDPLIRAGAPAGWTVADKSGHAD-ALRNDVAVVFPPRKDQIVIAIMTEN +NDPDTESDAALIEDTAHAALGAf +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A359KBV5_9CAUL +------DLSALEARHGGRLGVSVAT--EGQRA-AWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRAIPVTQADMISHAPVTEPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL +EPFRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLLVDTPLSPASKT +LLMRWLVDTPTGQGRIKAGVPAGWTVAHKTGTGGYGPVNDIGVLYPTDGAPIAIAVYFHA +TKSTDAQREAVIADATRQALK-- +>[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas bullata TaxID=13160 RepID=UPI000E0AA8A6 +---LDLDLSDLEARHGGRLGLAVAS--AGVNA-AWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRAIPITAADMINHAPTTEPAVGSTLTVEQLMKATVELSDNPAANILIREMGGL +EALRAFYRGIGDDSTRVDRLEPEMNRA--DGDKDTITPIQSVQNISRLLVETPLNAASKA +LLMRWMIDTPTGQGRIKAGVPAGWAVAHKTGTGGYGPTNDIGLIQPPAGAPIVIAVYFHA +TRSTDAQREAVIADATRLALK-- +>[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Chitinophaga sp. YR627 TaxID=1881041 RepID=A0A1I4ZSR1_9BACT +--NTRQKVNEIAATARGHVGMAMMSLESGDTM-TLNGNDHFPMQSVFKVPLAIAVLDQVD +KGKLSLDQVIHITKKELLPWSPIREKYPEGTLKLREVLAYTVSQSDNNGCDILFNLVGGT +AYVEQYIHGLGIDSMAIKANEERMASAWKVQYTNWSSPLATLQLLKGIHTGKYLSKSSND +FLLKIMKETTTGPKRLRGMLPSDAVVAHKTGSSDTAATNDAGIITLPDGSHLAIVVFVSD +TKVNEAIREGVIARMTRLFWD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A411G5Q4_PROMI +-------------------------------------EERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYTPVTEKHLTDGMTVRELCSAAITMSDNTAANLLVTTIGGP +KELTAFLHNMGDHVTRHDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRG------------------------ +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1B1 TaxID=2080528 RepID=A0A2S5YG18_9MICO +---VSAELAALESEFDARIGVSAVDTGSGRRV-EHRSNERFGYASSLKALAVAEFLRTVP +--AAERDEVVTWTAADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRIGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGEVLSAEDRA +LLLAWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILTAR +NDPEADYDDALVARAAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Acinetobacter sp. Tr-809 TaxID=2608324 RepID=UPI00142352F4 +--TLEDQIKTL-SDKGWQIGVSILDMD-DKLI-SINGDKRFPLDSTVKALACANVLAKVD +AKKLSLDHSKTIQQKDLVTYSPVVKEYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP +VGLTSFMRSIGDKVTRSDRYEPDLVINPEGDIRDTTSPNAMNTSMKKLLVGNVLSTSSKE +QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGLTSMVWSESHAPVFISIYVRK +SETSLDERSEVIKLLSDHIVK-- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus capitis TaxID=29388 RepID=UPI00071289EC +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDDTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A1V0QSV5_PSEAI +----SAKLQSLEAG-QARLGVCFLDTVTGEVS-GNRIEERFAMCSTVKLAIVAACLREAD +KARLNLEEILTYSEADLLPWAPVTRKNLAKGLSISALAQAAQEMSDGVAANLLIKRLGGP +AAVTAKFREMGDSVTRLDRYEPDLGLVLSADVRDTTTPLAYAQLVRRITTGRVLSHGSRE +QLLEWMRNTVTGASRLRAGLPTEWRTGNKTGTGRTNKCNDVAITFPPSKNPIIIAAYFDS +GEKVEARHEAVLAEVGKIAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. BK227 TaxID=2512162 RepID=UPI00104E6479 +-----DALGALERRQGGRLGVFAVDAGSGRTL-AHRADERFMLFSTFKGVLAAAVLADVD +AGTEAFNARVSYTAADLLPASPVTRAHLDEGLTVMALCLAIMHKSDNAAANLLLARRGGP +AHLTAFVRRLGDAVTRFDRYETAAG--TPSGIRDTTTPRAIVSTVRALLLGDVLSATSRA +TLEAWMAGNEVGRSRLRATFPADWAAGDRTGTGN-GYCNDYAFARRPGKPPLLVSAYFEA +PGMTLAKQEAVLRQVGAIIV--- +>[subseq from] class A beta-lactamase n=1 Tax=Azospirillum sp. B506 TaxID=137721 RepID=UPI0005B28A7F +---------------------------------------------------------TVD +EGKDRLDRRIPVTKADLLPYAPFSETRLNGTPTLAELCEAAVTLSDNVAANLLLPGVGNP +AGLTAFLRAIGDKTTRLDRNEPTMNTAIPGDPRDTTAPAAMVRSMERLLLGDALRPDSRQ +QLTGWMVANKTGDKRLRAGLPAGWRVGDKTGTGANGTANDIAILWPEGRAPLLVASYLTQ +TAEGFKQQDSIHAEVARTVAGL- +>[subseq from] class A beta-lactamase n=1 Tax=Aeromicrobium sp. zg-629 TaxID=2663859 RepID=UPI0012B57622 +--QIADRLAALEEQHDVTIGVSAVDV-QGKRV-EYRAGDRFGYASTVKAFAAATMLAEKT +--PQERAKTVRWTQADIDAYSPVTSEHPERGLTLDELAEAAVRDSDNTAMNLVLRSVGGP +EAVEKFLRTLGDDRTQLDSYEPDLNTVTPSQVANTTTPTAFATALQAAVETKAIAPRERR +TLLDWMGGNSTGDTLTRAGLPAGWEVADKSGGAG-GLRNDIGVVTGPDGQTVYLAVFTST +NDPEAEYDDVVVEEAARAVLAEy +>[subseq from] class A beta-lactamase n=1 Tax=Brachybacterium sp. YJGR34 TaxID=2059911 RepID=UPI000E0B9D36 +-----AAFGDLEAEFAARLGVYAIDTGTGEVV-EHRADERFGFASTIKLFAAAELLDATT +--ESELETSIDVPE-TVLAHSPVLEEHAGGTVTLAEAIDASLVSSDNTAADFVFDQLGGP +EALEERLRAIGDDTTRVARSEPELNDIAPGDERDTSTARAFATSLRAYTVADTLAEDDRA +ALVDAMVRSTTGDALIRAGAPTGWTVGDRSGAAGYGSRNDIGIAYPPDGAPVVLVIFTDR +AAEDADFDDALLAEATQVVFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBA15_016 TaxID=1898740 RepID=UPI0008DDE5CA +--AVARTLADLEREYDATVGVVATDTTTGETV-AYNGDRRFGYASTLKAFAAAQFLRAVH +--GADRDERVRWSAADATAHSPVTSEHVADGLTVAQLAEAAVRQSDNLALNLVLDRIGGP +AGLDRALAELGDRTTEVVHDEPALNTIEPGSTEDTTTPAAFAATLATVLDGQTLGRSDTA +LLEHWMSGNTTGDTLVRAGAPDGWTVVDKSGGAG-GIRNDVARVTRPDGGPIVIAVLTTR +NAPDTAYDDALVARSAAAVLDAf +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000CE7AE7B +---VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR +NDPEADYDDALVARAAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia speluncae TaxID=419477 RepID=UPI0009FD2A22 +--ELSNSLMEIQERHNVLFGIAAYSPTGARTF-EWNAADRFALTSTFKVYAVAALLRLAE +RGEVDLNERVPILHADIVIASPTTSYRAGETLSWYDLCQAALVRSDNTAANLILRRIGGP +PAVTALARMIGDTETRLDRWEPALNEALPGDTRDTSTPAAFAGGLHRLVLGNALIPVHRR +MLTGWMRSSVTSGDRMREGLPVGWVAADKSGTGAYGTVNDAGVVWSPTGTSVVLVIFSRS +TIPMAAPSNKAVADATTAVL--- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas viscosa TaxID=871741 RepID=A0A1I6QFA6_9CAUL +-------LSALEARNGGRLGFAAMDLARGRNL-VWRGGERFVYCSTFKSYLAAATLLRVQ +SGAERLERLIPVTRADMVLHAPTTGPAVGSTLTIERLMEATVGLSDNPAANILIRELGGI +DALRAFYRGVGDDITRVDRLEPEMNRL--DGDKDTTTPLQSMRNLVSLLVSEPLSPASKA +LLLRWMTETPTGAGRIKAGVPAGWTVAHKTGTGGYGPSNDIGVLYPPAGEPVVLAVYYHA +TPESAASNDAVIAEATRMALDAf +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1E2 TaxID=2080550 RepID=UPI000CE8E411 +---VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEEATATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVSEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSTR +NDPEADYDDALVARAAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia carnea TaxID=37328 RepID=UPI0009D92B6C +--DLSNTLMEIQERHDVLFGIAAYSPTGARTF-EWNAADRFALTSTFKVYAVAALLRLAE +RGEVDLNEQVPILQEDIVIASPTTSYRVGETLSWYDLCQAALVRNDNTAANLILRRIGGP +PAVTALARMLGDTETRLDRWEPALNEALPGDTRDTSTPAAFAGGLHRLVLGNALIPEHRR +MLTGWMRSSVTSGERMREGLPVGWVAADKSGTGAYGTVNDAGVVWSPTGTSVVLVIFSRS +TIPMAAPSNQAVADATTAVLE-- +>[subseq from] Beta-lactamase AST-1 n=1 Tax=Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL B-2516) TaxID=278992 RepID=A0AC32_STRA7 +---LSKTLRALEKSYDGRIGAVGIDLGDGRTV-AYRADERFPFNSSFKVFACAAVLDKAR +TGDGLMEQVVRWEPADMAGNSPETTEYTDTGMTPAQLCRAGITKSDGFAGNLLLEQIGGP +RGLTAFFRAVGDRSSRLDRPEPRLTEWEPGGVRDTTTPAAAARTFTELTTGDTLQGGDRA +RLVGWLKASVTGADRIKAGLPKDWTVGNKTGTGGHGTASDLAIVWPPGTAPLILSVYTNR +NHDNTAHDDKVIASTATALA--- +>[subseq from] Beta-lactamase n=2 Tax=Chitinophaga ginsengisoli TaxID=363837 RepID=A0A2P8FZF6_9BACT +-nTVRKKIHDIAQTAHGHVGMAMMSLEDGDTI-TLNGKDRFPMQSVFKLPLALAVLDQVD +KGKFSLGQVIHIYKEDLLPWSPIREKFPEGTMKLSDILAYTVSQSDNSGCDLLFRLVGGT +AYVEKYIHSLGIDSIAIRATEEQASKAWGVQYTNWSSPVAMLQLLKGVHTGKYLSKSSND +FLLKLMTATTTGPKRMKGMLPEGAVVAHKTGTSDTAATNDVGIVTLPNGKHYGIVVFVSD +TKADTAIREGVIAQLTRLFWD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Auraticoccus sp. F435 TaxID=2656650 RepID=A0A6A9V2L4_9ACTN +------RLGELERRHDVTIGLWARNLRTGREL-AHRADSRFPICSVFKALAVAALLRGVV +PDAHVLRRPAHIPPAALLEVSPFVEQCLRDGPTVEQLCVATLQLSDNTAGNEVLARIGGP +TAVTRFARSLGDTTTRLDRWEPELNSAEPDRVTDTTSPRAVGRTVAGLLTGRSLPRRDRD +RLTGWMLGSTTSAERLRAALPPGWQLADKTGGGSYAVNNDVGVAWAPDGTPLALAVMVRS +DDPAAVREDTVVAEVGRLCV--- +>[subseq from] Beta-lactamase n=1 Tax=Enterobacteriaceae bacterium TaxID=1849603 RepID=A0A351NQD5_9ENTR +----------------------IVNADGQPIF-GYRQSERFPLTSTFKVLACAALLDRLH +KTAGSLNETVTIKPDELLSYSPITKNYVAPAITLQTLCSAAVSYSDNTAGNSILAYLGGP +DAITRFMRESGDDVTRLDRTEPTLNEATPGDARDTSTPERMASGLHTLLGTPRLTAPHRE +MLEQWMRDDKVADNLLRAALPEGWAIADKTGAGGYGSRAIIAAVYPKGAQPVYMAIYITQ +TDAEMKMSDGVIKGIGERVF--- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium pusillum TaxID=69373 RepID=UPI0011A68EF1 +--AVAKALAALEQQYDATVGIVATDTTTGETV-SHNGDRRFGYASTLKAFAAAQFLRSVH +--GAARDERVHWTAADVTAYSPVTEQHVSDGLTYSQLAEAAVRQSDNTALNLVLKRIGGP +KGLGDALTELGDATTQVVNDEPALNTIEPGSTEDTTTPAAFTADLARVFDGHTLDASDTA +QLQDWMSGNATGDTLIRAGAPKGWTVADKSGGAG-GIRNDIARVTTTDGHEITISVLTTR +NDPAAKYDDALVAKSAAAVLQAf +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas diminuta TaxID=293 RepID=A0A2X1C7J8_BREDI +------DLSALEARHGGRLGVSAAT--EGRSA-AWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDQAIPVTQADMISHAPVTEPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL +DALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLLVDTPLSPASKT +LLMRWLVDTPTGQGRIKAGVPAGWTVAHKTGTGGYGPVNDIGLILPPTGAPISIAIYFHA +TKSTDAQREAVIADATRQALK-- +>[subseq from] class A beta-lactamase n=1 Tax=Yonghaparkia sp. Root332 TaxID=1736516 RepID=UPI0009EB5DF5 +---VAAELAALETEYGATIGVLARDTSSGASI-AFGQDRRFGFASTMKAPLAGVFLDRVE +--GAARDEVVRWSAAQVEEYAPVTAERIDEGLTLAELAEAAVRQSDNLAFNLVLERLGGP +AALDAALAELGDETTEVVNLEPALNTIEPGSTDDTTTAAALAGTLEALLLGPTLDADDRT +LLLDWMSGNATGDTLIRAGAPEGWVVADKSGGAG-AIRNDVALVTRPDGAPIVIAVLTQR +DDPEAERDDSLVARAAEIALDAf +>[subseq from] Beta-lactamase Toho-1 n=2 Tax=Altererythrobacter namhicola TaxID=645517 RepID=A0A1C7DBC0_9SPHN +---VAVEIAALEQTSGGTLGACLLDTASGALL-GHRLDERFGHCSSFKTSLAAMVLAGAD +NGTLDLSEQMAWEETAMLGNSPFTMDRLGTGATLAELARAVQVASDNTAANVLLGRLGGP +EAVTAFWRELGDETSRLDRTEPQLNNAPAGDPRDTTTPRAMAQTLAKIATGDVLAPESRA +TLLGWMAETTTGTRRIRAGLPEVWQAANKTGTSLGSLYVDIAVLTPSGATPLVLTGYFRA +NETHQPEGEAVLARLGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis witflariensis TaxID=173675 RepID=A0A246K5M3_9SPHN +-----KQIAEIEKRSGGRLGVAVTDSQGDLLF-GHRADERFAMCSTFKLLLAGQVLERAA +-DGVSLRTPLSFTRADLIAHSPGTEKLLGADQRLGAAARDAVVLSDNAAANLILTQMGGP +AVFTAALRGAGDDVTRLDRIEPELNENAPGDPRDTSSPAAMAKSAAAYVYGNRLTGDYRK +QLRDWLIESETGLARIRGGLPTGWLSGDKTGTCGT-AYNDVAFVEEPGGAKYMIAVYLDR +PAVKGDAANAAIADVARAVAR-- +>[subseq from] Class A beta-lactamase n=2 Tax=Hyphomonadaceae TaxID=69657 RepID=A0A2D7IYK3_9RHOB +-----TAIGYAESQNGGRFGVSAVNLATGETI-THRGDERFAMCSSFKWLLAALVLQRVQ +AGDEALDRVIEFTEADMVSHAPVTQSALADGLSVEALCRGTVQTSDNPAANLLLRTLGGP +EGFTAMLRADGETTTRLDRWEPELNENAEGDPRDTTTPNAMVSLMGFYLFGAGLSAEYQT +LLKDWMIGASTGLTRLRAGIDAPWASGDKTGTSSNNQSNDVAFAYKTAADPILISSYLNV +ADPMSEETNALHATIGRQIM--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WTV1_9BACT +-nELRDRIEQISQAARGRVGVTATVLETGESV-TLNGDRQFPMQSVYKFPIGMAVLAQVD +RGKLKLDQKIRVEARDFVSHSPIRDENPQGLLSLAELLKYMVSESDGTACDVLLKLVGGP +EVVTQYLRDLGVNGIVVANTEKEIGQDKAVQYRNYASPNAAVVLLQALHEGQGLSESSQA +LLRKLMTQTPTGLQRIKGLLPDGTVVAHKTGTSRTAATNDVGLVTLPNGRHMAIAVFVSD +SGANNATREGVIAKVTKAAWDEw +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas diminuta TaxID=293 RepID=A0A1Z3LZR5_BREDI +-----LDLSALEARHGGRLGVSAAT--EGRRA-AWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRAIPVTQADMISHAPVTEPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL +DALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLLVDTPLSPASKT +LLMRWLVDTPTGQGRIKAGVPADWTVAHKTGTGGYGPVNDIGLILPPNVAPIAIAVYFHA +TKSTDAQREAVIADATRQALK-- +>[subseq from] Beta-lactamase n=2 Tax=Frigoribacterium faeni TaxID=145483 RepID=A0A511A7R5_9MICO +---LDAPLAALEAEYDALVGVSALDTGTGRRV-DHRADERFGYASTIKAFLAAQFLHDVP +--AAERDERVTWTQSDVDAYSPVTSEHVDDGLTLAELVDASVRFSDNTATNLVFDRLGGP +TELDTSLAALGDETTEVVNVEPALNDVEPDGTDDTSTAAAFTADVTTILTSDVLADSDRA +SWVDLLTGNATGDTLIRAGAPEGWTVADKSGGAGP-IRNDVAIVTPPGRDPIVLTILTTK +NDPDAAYDDALVADAARVVLD-- +>[subseq from] Uncharacterized protein n=1 Tax='Candidatus Kapabacteria' thiocyanatum TaxID=1895771 RepID=A0A1M3KZ26_9BACT +--EARRQIAKIIQSSNAKVGVSVLGLEDRDTL-AFDGKGHYPMQSVYKFPLAVAVLHEVD +RGKLSLDMKIHVRKKDLLPWSPMRDKYPKGELTLSEILRYTVSQSDNNGCDILFRMLGGP +AKVEAYIRSLGITGMAFAATEEEMHERPKTQFSNWCEPEAMVKLLDMFHGGRILSESSRK +FLWNAMAETSTGPDRIKGLLPPGTTVAHKTGSSGRNALNDVGIVVLPKNRHVAIVVYVSD +SHEDNDTLENVIARISKIVWDYf +>[subseq from] Class A beta-lactamase n=1 Tax=Siphonobacter sp. BAB-5385 TaxID=1864822 RepID=A0A261Q5Y5_9BACT +-kSLQNQIEQLIQPKKATVGVSIYDFASKQTL-LIHGDKHLPMQSVYKFHVALAVLKEVD +KGRFKLEQKLHVKKSDLVPHSPMGEDHPNGELPLSEIIRYMVSESDGSACDYLFRLLGGP +TQVNAFIHQLGIKEVAIRETEETMQANWDVQYTNWTTPAAMLDLLKLFYQQKILSKRSHD +FLWKVMTETVTGENRLKKLLPTGTLVIHKTGTSGMGAVNDVGFIALPNGKHIAISVFVTN +TSEGIEKNEQIIADIAKLAYDHf +>[subseq from] Beta-lactamase class A n=2 Tax=Pelomonas saccharophila TaxID=304 RepID=A0A4R3ULZ2_PELSC +------DFAALERRVQGRLGLFAIDTGSGRTL-AHRADERFATCSTFKILLAARVAQGVE +RGRWQWRDEIALHKSDRVPYSPVFDRLLPRGATLAELVTGILVESDNPCANLLLRHCDTP +VGFTTWLREQGDEVTRLDRHETELNENSPGDPRDTSTPRAFAKTLQRLLVGEGLARDSQA +RLRADLQASRTGLARLRAGVPEGWRVLDKTGTGKRGAINDVALVYPPDGGPWVIAALQSD +SRAATDELSEVHADAMRLIVKAw +>[subseq from] class A beta-lactamase n=1 Tax=alpha proteobacterium L41A TaxID=1229204 RepID=UPI00037D96A5 +-------LSDLEARNGGRLGFVVQDAATGRKL-VWRGEERFVYCSTFKMYLAAATLLRVQ +AGQERLDRRIPITTADMIDHAPVTEPAVGDSLTVEQLMKGAVEVSDNPAANLLLKAMGGP +SAMQTFYRGIGDVSTRSDRFEPEMNRL--DGDKDTILPSQSVANLQRLFLDPALTTVSRA +LLLQWMTDTPTGQNRLRAGTPADWRVAHKTGTGGYGPTNDIGLLYPPSGQPVIVAAYYHA +TRATDDANAAVIAEATRRAL--- +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI000734A824 +--ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP +--HNELNNKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY +KEVNKRLKSLDDKTTKPSRMEPELNIYDPKSNRDTSTPQAFGKTLNKLINDGRLSKENKA +FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSETAKVVLEKf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4V2ABD3_9BURK +------------------------------------------------------------ +--------------ADLVSYSPVTQKHAGDGMTVAGLCAAALQYSDNTAGNLLIRLLGGI +DAVTAYARGIGDSAFRLDRWETELNTAIPGDPRDTTTPAAMATSVQRLALGDALGAPQRA +QFVAWLRGNTTGATRIRAGVPADWELGDKTGTGDYGTTNDVAVLWPPGRPPLVMAIYFAQ +PASDAAARNDVLASAARIV---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1B2ZDJ9_KLEPN +----------------------------------------------SKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGA +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGNALADTQRA +QLVTWLKGNTTGSASIQAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLILV----- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. VKM Ac-2762 TaxID=2609254 RepID=UPI00132EB15E +---VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR +NDPEADYDDALVARAAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1A4 TaxID=2080522 RepID=UPI000CE8AEB8 +---VAAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Rathayibacter sp. Leaf294 TaxID=1736326 RepID=A0A0Q5AV24_9MICO +---VSAELAALESEFDARIGVSAVDTASDRLV-SHRQDERFGYASSIKVLAAAQFLRAVP +--AAERDEIVTWTAADVEAYSPVTSESIGEGLPLSELAEAAVRRSDNTALNLVLARLGGP +SALDRGLEDLGDTTTEVVDDEPALNTIEPGSTANTTTPAAFTAALRAVTLGTALPGEDRA +LLLDWMSGNATGDALVRAGAPSGWVVADKSGGAG-GIRNDVAVVTPPGRDPIVLSILTAR +NDPDAAYDDALVARSAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces ambofaciens TaxID=1889 RepID=UPI0007B4242E +---LSKTLRALEKSYDGRIGAVGIDLGDGRTV-AYRADERFPFNSSFKVFACAAVLDKAR +TGDGLMEQVVRWEPADMAGNSPETTEYTDTGMTPAQLCRAGITKSDGFAGNLLLEQIGGP +RGLTAFLRAAGDRSSRLDRPEPRLTEWEPGGVRDTTTPAAAARTFTELTTGDTLQGGDRA +RLVGWLKASVTGADRIKAGLPKDWTVGNKTGTGGHGTASDLAIVWPPGTAPLILSVYTNR +NHDNTAHEDKVIASTATALA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium SYSU XM002 TaxID=2605990 RepID=UPI00135A4481 +--ALTKQLAAITAPLVGRVGVAAKLIGSNNVI-ALNGDELFPMASVYKVPAAVAALRKVD +AGQLSLNQLVEIKPDDLSAGDNVIATHPGIQLSVANLIEAMITESDNTATDMVFDVAGGP +SNITSTMRSLGITGMRIDRNTKELMTAYEADPRDQSTPLAMLELLMQIEDAKATSRSSRD +FLLASMSRTRTGPGRLKGLLPRGTPVAHKTGTSS-GVANDVGYITLPDGRRFIVVVFTKS +SSTPRPDRDRAIAEVARTLFDYf +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. BH-2-1-1 TaxID=1905847 RepID=UPI00089DF594 +--AVDRTLADLEREYDATVGVVATDTTTGETV-AYNGDRRFGYASTLKAFAAAQFLRAVH +--GADRDERVRWSAADATAHSPVTSEHVADGLTVAQLAEAAVRQSDNLALNLVLDRIGGP +AGLDRALAELGDRTTEVVHDEPALNTIEPGSTEDTTTPAAFAATLATVLDGQTLGRSDTA +LLEHWMSGNATGDTLVRAGAPEGWTVVDKSGGAG-GIRNDVARVTRPDGGPIVIAVLTTR +NAPDTAYDDALVARSAAAVLDAf +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0005DB91DD +------------------------------------------------------------ +---------IHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=6 Tax=Pseudomonas TaxID=286 RepID=E9N9H5_PSEAI +--TASDALAALELRNGGRLGVFALDAGSGRSL-GWREDERFGMCSTFKLLLAATVLDAAR +QGRLDGTAPIHFSDDDLVPHSPVLREHLALGLTAPELARATQLTSDNAAANLLIRKLGGP +EAVTALWRASGDEVSRLDRLEPDMNLLPPGDLRDSTSPRAMAQHVARLFTSEMLVPEDRE +RLREWMVETGTGLARLRAATPPHWQAGDKTGSAIPNKTHDVAVFWPPGRAPVIVAAYYES +DAHHRAQDEAVLAQVGRIAV--- +>[subseq from] Beta-lactamase n=2 Tax=Pseudarthrobacter chlorophenolicus TaxID=85085 RepID=B8HGJ3_PSECP +-qRLDTALSGLESAHGLTIGVSAGRLGQRPAY-AYRGENTFPMCSLFKTLAVARLLRDHA +YDDGFWQRRISFRKNQIVRDSVICAADKDRNMSVEELADAALRFSDNTAGNLLLELIGGP +PEIGAYARSLGALSTRLDRWEPELNEALPGDVRDTSTPSDIHTLYEALLLGDALDTLGQA +RLRGWMLRNATSGERLRAAVPPGAELADKTGAGSYGVVNDAGVVWPEDGPPLTLAVMTRT +SRPDAVNNNAVVARVGQLVF--- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas subvibrioides TaxID=74313 RepID=A0A258FRL9_9CAUL +-------LSALETREGGRLGFAAKDMQTGRIL-TWRGEERFVYCSTFKMFLAAATLMRVQ +AGEERLDRMIPITRADMINHAPVTEPAIGGSLSVEALMKGTVEVSDNPAANLLLKAMGGL +EPMQAFYRGIGDATTRVDRFEPEMNRL--DGDKDTILPLQSIANIERLLVDTPLSEASKA +LLLKWMVDSPTGTARIKAGVPAGWTVAHKTGTGGYGPTNDIGVLYPPSGAPVIVAAYYHA +AG-DDPKNEAVIAEATQAALA-- +>[subseq from] class A beta-lactamase n=1 Tax=Frigoribacterium sp. Leaf172 TaxID=1736285 RepID=UPI0009E8C170 +--DASAELTALEAEFDARVGVSALDTGSGATL-VHRQEERLGYASTIKVFAAAAFLHDVP +--VDQRDEVVTWTAADVAAYTPVTSQYVDGGMSLVALAEAAVRTSNNLALNLVLDRIGGP +AGLDRALEQLGDTTTEVVADEPALNTIEPGSTDDTTTAAAFTADLAALATGDHLAAADRA +TLLDWMSGNTTGDALIRAGAPDGWTVADKSGGAG-GIRNDVAVVTPPGRDPIVVTILTER +NDPDAAYDDALVARVASVVLA-- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter boissieri TaxID=1219383 RepID=A0A1G6H2V6_9GAMM +---------DLLSKKGWQIGVSILDMD-KTVV-SINGDQRFPLNSTVKAIACANVLSKVD +ANKLTLDTSKTITKDSLVVYSPVVKNYVNKKLTLKEACQIANAYSDNTAANFIISEGGGP +EGLTAFMKSMGDDITRSDRYEPDLTVNPEGDIQDTTSANAINLSLKKLLTGHVLSEYSKE +QLKQWMMGNKVADNMLRAVLPPNWKIADRTGASDYGIRGLIAMVWSDNHTPVFISIYVRK +NGSSVDERSKVIKQLSEHVVKEy +>[subseq from] Beta-lactamase n=1 Tax=Glycocaulis sp. ZYF765 TaxID=2518983 RepID=A0A550K9M2_9RHOB +--AMEARIAALAELSGGRMGVMAFDLAGGEPV-SLNPDEPFPMASTFKIAVAAAVLARVD +AGELALGDMIEIDPDSHVMSEVIADRFIHPGLSVANLIELTITQSDNTATDVLTDLAGGP +EAVTAWLSAQGIEGQRIDRDTASLLRPFDTDPRDTSTPRAMAELLARIARGQALSETGTD +FLMGALSRTRTGAGRLRGLLPEGTPVAHKTGTIG-GTVNDAGIITLPDGRRIVVVAFVKQ +SDAPMAARERAIAEIARTLHDGf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chitinophaga sp. H33E-04 TaxID=2703787 RepID=A0A6B9ZJV7_9BACT +--NTRKYIHETTAAAQGHVGMAMLTLQGKDTM-SFNGNDRFPMQSVFKVPLALAVLDQVD +KGKLKLDQIIHIRKEELLPWSPIKKKYPDGTMPLSELLAYTVSQSDNNGCDILFRLVGGT +DYVDRYVHSIGIDSISIKATEEGMAQAWNVQYTNWATPVAILHMLVGIEKGSYLSKSSND +FLLKIMRETTTGPGRMRGLLPKDAIVAHKTGTSDTAATNDAGIVTLPNGKKYAIVVFVSD +AKADEATRDGVIAKLTRLFWD-- +>[subseq from] Beta-lactamase n=1 Tax=Tolypothrix bouteillei VB521301 TaxID=1479485 RepID=A0A0C1N4A3_9CYAN +-nKLRDLIEQISHAAQGRVGMTATVVETGESV-SLNGDRRFPMQSVYKFPIAMAVLAQVD +QGNLKLDQKIRVAASDIVRDSRILEKNSQGKFRLAELLKYMVSESDSTACDVLLRLIGKP +QRVTEYLRNLDVNDIVVANTENEIQKDRALQYRNYATPDAAVNLLRAFHKGRGLSKSTQA +LLRQWMIETSTGPNRIKGLLPKGTVVAHKTGTSATAATNDVGIVTLPNGQHLAIAVFVSD +SQATNAIREEVIAKLAKAAWDEw +>[subseq from] VEB-PER_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WLK9_9BACT +-eALRKRMEEITQTAKGKVGVAVLGIEDRDTL-SVFGKDRFPMQSVYKFPVAIAVLHQVD +QRKLSLQQKIHLRPEDLLPWSPLREKYPQGNIPLSEVLLNTVALSDNNGCDVLFRLLGGP +PKVDAYIRSLGVRGMAIAATEEQMHQEEQVQYTNWSEPTAMLRLLDVFYARKALSPASTD +FLWKVMVETSTGPRRMKGLLPPGTIVAHKTGSSGTAATNDVGIVTLPNGKHVALVVFVSD +ASADEATREGVIAQITKAVWDYf +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus C0673 TaxID=1413510 RepID=A0A033UR43_STAAU +--ATTQDLKKVEDKYDANVGVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP +--HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY +KEVNKRLKSLDDKTTKPSRMEPELNNYDPKSNKDTSTPKAFGKTLNKLINDGRLSKENKA +FLIDLMINSKSGDTLIKKGAPKNFKVADKSGQATYASRNDIAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSETAKVVLEKf +>[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. RIFCSPHIGHO2_01_FULL_70_10 TaxID=1801945 RepID=A0A1G2WPP5_9CAUL +-------------ADNARFGAAMINLESGELW-AFNGSDRFPMMSVFKAPLGAAVLAEVD +AGRLDLDETITLTDEDLSPFSPIADAYPGRRYTVGQLLELAVGQSDNTAADVLMRRIGGP +GVVTAWLRAHRIDDMRVDRYERQMQPAYMRDPRDTTTPRAALLFLSKLSAGELLSEASTE +RLLTLMSETTTGADRLKAGLPEGARLAHKTGTARTDATNDMGIITLPDGRRYAVAVFLSG +SPLDGESREAVIADFARLAVR-- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A2A3WZV9_9MICO +-qKVSGELESLEEDFKARIGVSAVDTGNGTSF-DYRSDERFGFASTLKVFAVAELLARTT +--SADLDEQVTWTQTDVDEWTPVTEKHVDTGLPLRDVAESALRVSDNAAMNIVLDEIGGP +QGLDAALEDAGDPTTEVIDEEPELNDVDPDSSDNTTTPKAYTADLQGLLDPDRLPEDDRE +VLLEWMSDNETGDPLIRAGAPKGWTVKDKSGHSD-GIQNDIAVVYPPNEDPIIITVLTQS +DNPDSEDGPTLVAAAAEAVFDSf +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium citreum TaxID=2036 RepID=A0A542FN41_9MICO +---TRQAFADLERRDGARVGVVAVDTGTGRSL-GYRADERFAFASTNKVQIAAAVLAASS +--PADLDEVVHYDRGDLLSHAPVTTPAVDTGLTVRQLVDAAIRQSDNTAANLLVERVGGV +AGVTRWLRGLGDTTTDVSRTEPDLNTAVPGDRRDTTTAAQSAADLRAVLLGDALDADDRS +LLRDSMLGTTTGASTIRAGVDPSWTVADKTGTASYGVRNDVAVVTPP------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Amantichitinum ursilacus TaxID=857265 RepID=UPI0013793255 +---AARQLAQIETTAGGRLGVTALDTGSGKWL-TYRPDERFPLAGAFTPLLAAAVLARVE +KDQEQLSRPILFTAADLQPWAPIARTRLKAGMTVADLCAAAIQFDDHAAINLLLNSVGGP +TQLTNWLRTQGDDISEIDRFEPELTSAIKGDVRDSSTPAMMLKMLNRFLLSDALAIESRA +QLQAWLVGNGNATTRIRAGLPPEWRVGNATGNGENGTTNDLAIIWPPPRAPILLTVWLTD +SKATGAVRDAALKEVARVVFA-- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. VKM Ac-2804 TaxID=2609257 RepID=UPI00132F280B +---VSADLTALEAEFDARIGVSAVDTGSGRQV-AHRRDERFGYASSIKALAAAEFLHAVP +--AAERGDVVTWTAADVEAYSPVTGESTATGLPLARLAEVAVRQSDNTALNLVLDRLGGP +TALDRALEELGDTTTDVVDEEPRLNTVVPGSTANTTTPAAVTADLTAVALGERLPVEDRA +LLLDWMSGNATGDALIRAGAPEGWSVADKSGGAG-GIRNDVAVVTPPGRAPIVLSVLTAR +NDPDTAYDDALVARAAAIVL--- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas diminuta TaxID=293 RepID=A0A410NWQ6_BREDI +------DLSGLEARHGGRLGVSVAT--EGRSA-AWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRAIPVTQADMISHAPVTELAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL +DALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLLVDTPLSPASKT +LLMRWLVDTPTGQGRIKAGVPAGWTVAHKTGTGGYGPVNDIGLILPPNAAPIAIAIYFHA +TKSTDAQREAVIADATRQALK-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NP160 TaxID=2586637 RepID=A0A5C4X8Y6_9ACTN +----AGQLTALEESSDSRIGLFAVDTATGRFV-AHRAEERFAFASTGKVLTAAAVLEATD +--DSELDAPTPVEPDDVVPHSPVTESRAGAAISLREAAEAAVTVSDNTAQNIMLEHLGGP +AGLEAVLRGAGDATTDPARYEPELNEVFSGDTRDTTTPRAMTASLRAYLVDGRLSPSDRD +ELVSWMEASTTGQDLVRAAVPAGWVVADKSGTPTSGGRNDVALVWPPGQAPWVITVFTDR +PGADAASVSGLVASATAAAVA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A2Z6A9U9_SHIFL +------------------------------------------MMSTYKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLIENSPVTEKHLTDGMTVRELCSAAITMSNNTAANLLLTTIGGP +KEQTAFLHNMGDHVSRRDGWGPELNEARPNDERDGRMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGGDGKASRIVVICTTG +GQATMDERNRQIAEIGASLS--- +>[subseq from] Class A beta-lactamase n=1 Tax=Brevundimonas sp. Root1423 TaxID=1736462 RepID=A0A0Q7SMG7_9CAUL +-------VSGLETRNGGRLGFVALDTATGRSL-GWRATERFVYCSTFKMYLAAATFVRIQ +DGRETADRMIPISRADMVNHAPVTEPAIGSSLSVGRLMQAVVEVSDNPAANLLLKANGGI +AAMQNFYRSIGDDSTRADRFEPEMNRL--DGDKDTIQPAQSVTNLQRLFLNSPLTAGSQA +RLLRWMVDSPTGADRLKAGVPAGWRVAHKTGTGGYGPTNDIGLLYPPNGKPVIVAAYYHA +TSSSAAANDAVIADAARLALK-- +>[subseq from] Beta-lactamase n=1 Tax=Luteipulveratus halotolerans TaxID=1631356 RepID=A0A0L6CMT1_9MICO +---------PIAQKHAVRLGVYAVDTGSRREV-RFHEDERFAYASTFKALASGLVLKKSG +--LAGLETAVAISAADLRPASPVSSRYVGKTMTMREIIDAAVRFSDNTAGNKLLTALGGP +AGFGTSLQALGDHVTRPSRYEVELSDGVPGDERDTSTARQLATDLRALLVDDVLPSPERA +FLRDTMWRNTTGDTTIRAGVPKGWTVADKTGTASYGGRNDIAVIWPPDREPVVIAVLSTR +DTQGSKGVDAVIAESTREVL--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000CE80907 +---VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPASFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPRRDAVVLSILSAR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. OK723 TaxID=2135605 RepID=A0A4R7BYA3_9BACT +-qTLRQQIAAIAGNISGKVGVYARVLETNDTV-SFNHDERFPMQSVYKFPVAMAILKQVD +AGKIRLDQPIKIQKADLTTHSPIREKYPEGNLTVKELLDYNICESDGSACDIFFKLLGGP +ANVNRYIHGLGVKQINIATTEEAQKEQPMVQYKNWCTPLAMTQLLEKFYTTSALSDSSRS +YLLHLMTTSGPGARRLKGLLPPGTVVAHKTGTAWTAAHNDVGIITLPNGNHIAITVFVSD +AKATEQERDATIAKITKAVWDAy +>[subseq from] Beta-lactamase n=1 Tax=Solitalea canadensis (strain ATCC 29591 / DSM 3403 / NBRC 15130 / NCIMB 12057 / USAM 9D) TaxID=929556 RepID=H8KP67_SOLCM +---FKDQIDQIAKEAKGDVGVALLNLEAGDTF-LYNETMHFPMQSVYKFPLAMAVLSQVD +AGKLTIDQKLHLTKRDLLPWSPLREKYPNANVTLMEVLKATVSESDNNGCDILFRLLGGP +KKVEKYIHGIGVKEIAIAATEEEMHTAWDVQFTNWCTPVAMQQLLSTFHKDDKLSEKSKQ +LLWDMMVDSPTGAKRIKALLPEGTVVAHKTGTSDTGAINDVGIIVLPNKHHLAITVFVAN +SKASTGIMEETIAKIAKAAYD-- +>[subseq from] Carbepenem-hydrolyzing beta-lactamase KPC n=1 Tax=Amantichitinum ursilacus TaxID=857265 RepID=A0A0N0GLR4_9NEIS +---AARQLAQIETTAGGRLGVTALDTGSGKWL-TYRPDERFPLAGAFTPLLAAAVLARVE +KDQEQLSRPILFTAADLQPWAPIARTRLKAGMTVADLCAAAIQFDDHAAINLLLNSVGGP +TQLTNWLRTQGDDISEIDRFEPELTSAIKGDVRDSSTPAMMLKMLNRFLLSDALAIESRA +QLQAWLVGNGNATTRIRAGLPPEWRVGNATGNGENGTTNDLAIIWPPPRAPILLTVWLTD +SKATGAVRDAALKEVARVVFA-- +>[subseq from] Beta-lactamase n=1 Tax=Dyadobacter sp. AR-3-8 TaxID=2576211 RepID=A0A4V6BLT4_9BACT +--IFRQEIDKIISASKSDVGVAIMGLEDKETF-LFNEGHKYPMQSVYKFPLAMAVLDQVD +KGKLSLNQKIHVTKKDLLPWSPLREKYPNGGIKISELIGYAVSNSDNNACDILFRTVGGP +EKVDQYIHGLGIKSIAIAATEEEMSKSWNVQFTNWCKPRAMLRLLDLFYKGKNLSKTSTN +FLMKTMTETTTGPNKIKGLLPKNTKVAHKTGLSGTNASNDVGIITLPNGEHVAVVIFLAH +TKLDEKSRDGVIAQISKEAYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Nocardioides insulae TaxID=394734 RepID=UPI00040918D3 +-------VGDLEARTGARIGLSARNLRTGSGL-AHRVDERFPLCSTFKPLVAAALLSRRV +----DLDELIRYRSSDLVDYSPVTGERR--AMTVGELADAAIRYSDNTAGNLLLRRLGGP +AALTAYLRSVGDDVTRLDRWETELNEGTPGDPRDTTTPRALAATYHRLLVGSVLPSRDRW +VLTGWMQSNTTSVAKFRAGLPTGWWCADKTGGGAYGTQNDAGLITAPDGTRIGFTILTRA +SMPDAVGDPTLMRSLAEL----- +>[subseq from] Beta-lactamase n=2 Tax=Chitinophaga niastensis TaxID=536980 RepID=A0A2P8HPT6_9BACT +-qTLRQQIAAISKNIPAKVGVYAMVLETGDTV-SYNRDQQFPMQSVYKFPIAMAILDQVD +KKKFTLDQPVMVNKSDIMPVSPIREKYPVGNIPLRELLQYNISASDGTACDVLLRLLGGT +TNANTYVRQLGVKQMTIATTEKEQQVDEMVQYRNWSTPAAMTALLTIFYEGQVLSDSSNA +LLLDLMITSGPGAKRIKGLLPPGTVVAHKTGTSGTRATNDAGIITLPNGHHLAIAIFVAD +AKADQDEREATIAKITKAAWDHw +>[subseq from] Beta-lactamase n=2 Tax=Listeria cornellensis TaxID=1494961 RepID=W7C5H9_9LIST +--KANAELKKLEEKYGATLGIYAVNTANNQKI-SYNDQERFAYVSTYKAIAGGLLLKNLT +--AEQLNKRVYFSKEDLVDYSPVTEKHVESGMTVKEIINAAMTYSDNTAGNILFHQLSGP +KGYQKELAKIGDKTTQANRFEPELNEAVPGDKRDTTTPEAMAKVLSFLVTKGNMASDRFD +YFKQTLIDNTTGDKLIRAGIPEGYAVGDKTGAGSYGTRNDIAVIYPKDGKPLVWVIYSKK +SG--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Cellulomonas sp. B6 TaxID=1295626 RepID=A0A0V8TAQ5_9CELL +---------------------HALDTVTGATA-SHRADERFAFCSTVKPLAAAAVLAAR- +-GVDGMDERVPVEAADLVTYSPVTEQRVGVGMTWRELVDAALRFSDNTAGNLLLAGAGGP +AALTAWLRGLGDDVTRSDRTEPDLNAFVPGDERDTSTPGALAGTYRTLVLGDALGGPERD +LLTDAMLRSTTGDALVRAAARPGWEVADKSGAGAYATRNDVAVVWTGAGAPVVLAVLSDR +ADPGAERTDAPVAEAARVVLD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WZB3_9BACT +-rELQKELEQIAAAAKGRVGVQAVVIETGETV-SLNPNEHFPMQSVYKFPIGMAVLQQVD +AGKLKLEQRVRVEKSDFVRRSPVRDKNPQGVLSVGELLRFAVSESDGTASDVLLKLAGGA +EAVNGYLKQLEVTDLVVANSEKEIGQDWETQYRNWASPESAVKLLRALYDGRGLSAQSQK +LLLKLMTETPTGPKRLKGLLPVGTIVAHKTGTSGNAATNDIGIVTLPNGRHLAIAVFVSD +SPANEATREGVIAKVARAVWDKw +>[subseq from] Uncharacterized protein n=1 Tax=Kutzneria albida DSM 43870 TaxID=1449976 RepID=W5WB78_9PSEU +---LERQLKELEASSHKHIGAFALDTGTGRTV-GYRTDERFPSLSTFKAVEAAAILDKAR +RDPGLLERTLHWTPDKEVPDGSTVNGHGAAGMTVSELASAAVTASDNTAANLLIEQIGGP +AGLTRYYRSLNDPVSRLDHTEPALNLWQPGEEQDTTTPAAMGRDLNQISLGSALTAQDRE +ILNGWLRSSKTGGERIRAGLPKDWVVGDKTGTINYAGANDIAVAWPPSHAPLVFTVYTYG +QQGS-TIDNKVLATVASALAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1B8 TaxID=2080533 RepID=UPI000CE8371C +---VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESAATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLVAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis macrogoltabida TaxID=33050 RepID=A0A0P0DX15_SPHMC +-----KAIRDLEARSGGRLGIAVVD-ARGKLVsADRGHERFAMCSTFKLLLAGQVLERAA +-KGVSLRTPLAFTRADLVSWSPGTEKLVGPDQQLGMAVRDAVVLSDNSAANLILKQMGGP +DVFTAALRRAGDSVTRLDRIEPELNENAPGDERDTTTPIAMATSAAGYVFGNRLGAGHRK +QLRGWMIESETGLKRIRAGLPQGWTAGDKTGTCGT-AYNDVAFVEAPDGRKYVIAIYLDR +PAVTGDDASAVIAEATRLTVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium algeriense TaxID=634784 RepID=UPI000D3BEFCD +-------LAAYERETGGRIGLYAENLASGAKI-VWRAEERFV-----KASLAAFVLARVD +RGEDRVEDMVAYGAADLLDYAPVAKANLAAGMSVSDMCKAIVELSDNTCANLLLARSGGP +AALTAFWRATGDTVSRLDHSEPELNRSPPGDPHDTTTPAAMAGNLRRFLLGDVLSMGSRE +HLTEWLVGCKTGNNRLRGGLPKEWKIGDKTGNNGKDASGDIAIAWPAAGGPVLVCAYTQG +GSPTPRQFESVFAEIGRMA---- +>[subseq from] Beta-lactamase CARB-3 n=1 Tax=Photobacterium leiognathi lrivu.4.1 TaxID=1248232 RepID=A0A0U1P6R2_PHOLE +------LLRQTEQQIDGKIGVAVFDTQTNTSW-NFNGNKRFPMMSAFKTLACANVLYDVQ +QHKLSLTNKIKVTKAGLINWNPVTQNFVGGQMSLNSVCGAAMLMSDNYAANLALEQVGGP +QGVTKFLRMIGDKTTRLDHFEPKLNYVEKGAENDTTTPIAMMNTIKKLLTGNVLDSENKA +QLKFWMTNNMVSDGLARAVLPTGWKIADRSGGGVNGSRTLTAMVWNKHHQPLFIGIFISN +SKETLPELNQVVASISAKIFNKy +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00066C709F +---HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKNDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAK------ +>[subseq from] Beta-lactamase n=1 Tax=Bacterioplanes sanyensis TaxID=1249553 RepID=A0A222FNZ2_9GAMM +-sALTQQVQTVEASIGARIGVAVLAPDGRRGW-HYQGDQRFALTSTFKTLLCAQLLNREG +----AANTMITMRQQDLVSYAPVMKTHIGETLSAAQLCGITLASSDNSAANLVLNALGGP +MALTEFLRQHGDTTTRLDRMETELNSAIPGDVRDTTTPVAMVRTLRHLLVEQGLSSSAQQ +QLRQWMINNQVADGLLRSVLPARWQIADRSGAGGHGARAITALVWPVGEQPWVLAIYIAE +TDAEFAQRNAAIVAIGEAVF--- +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI00066052FD +-kSTNDEIKKIEKKHNANIGMYALNTKNGKAL-SFNKDKRFAYASTFKTISSAMLLEKTP +--HNKLDKKIHITKDDIVPYSPVLEKYIGKDITLHKLIEANMLYSDNTANNKIIDELGGY +KQVKNRLENLGDTTTHPSRKEPNLNLYAPKDKRDTSTPLAYGKTLNKLITDGKLSKTNKD +FLLDLMLKNKSGDTLIKDGAPSNFKVKDKSGQATYGSRNDVAFVYPKGQKPIILVIFTNK +DKKDAKPNDKTVSEVAKVVLK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Yoonia litorea TaxID=1123755 RepID=A0A1I6MDV7_9RHOB +-tKLRETVASIEDTLDARVGLVIRQSGTDWSW-SHRGDERVLMTSTFKALLCGAVLARAD +AGTLDLDEALAITPSDLQDYAQVTEARVGTFMSIGDLCLATIDLSDNTAANLLIDRLGEP +GAVTDFLRSIGDEVGRLDRHEPALNTRSADGLSDTSTPDAMATSLEALLVGDALSPSSRA +QLREWMGLGGVTGSLLRAYVRDTWDVADKSGASAN-SRSLIAMVTPDAEAPYFVAIYISE +AEVGFERRNAALIALSAAVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000CE8EE53 +---VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAATEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPDSTEDTTTPAAFTADLAAVATGDVLSAEDRA +VLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR +NDPEAEYDDALVARAAAVVL--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000BBCB5E2 +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKXHINKDDIVAYSPILEKYVGKDITLKXLIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVXKDXKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas diminuta TaxID=293 RepID=UPI0006278A32 +------DLSALEARHGGRLGVSVAT--EGRSA-AWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRAIPVTQADMIRHAPVTEPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL +DALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLLVDTPLSPASKT +LLMRWLVDTPTGQGRIKAGVPAGWTVAHKTGTGGYGPVNDIGLILPPNAAAIAIAVYFHA +TKSTDAQREAVIADATRHALK-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. CNU-125 TaxID=1904961 RepID=UPI0009F86B45 +-aELNKKLRELEKAHKTRIGAVGIDLGTGKTV-GYRPDERFPFNSMFKVFACSAVLHKAR +TGSGLMDKVIRWTPEDMAGNSPETTEYTDTGMTPAQLCRAGITKSDGFAGNTLLTQIGGP +SGLTKFFRSTGDRVSRLDRPEPYLTEWEPGEVRDTTTPAASARTFTELTTGKTLHPDDRA +RLVGWLKASLTGAARIRAGLPEDWTVGDKTGTGGHGTAGDIAIVWSPGTAPMILSVLTNR +TTDDTPNDNEAIEHTATALAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. 52 TaxID=2035213 RepID=A0A2G6UKL4_9FLAO +-sALEQKINAITEGKKATVGVSVLGFENNFTY-SKNGDKNLPTLSVFKFHIACAVLDLVD +KGKLSLDQKIFFKKEDMLEWSPIRKKYPDANLSLSEVLDYTVALSDNNGCDMLLRLIGGT +QTVQKFMDSKGVKGFQIKRNEDDMHKNWKTQYDNYSTPNSAVQVLKKFYDGKLLSKKSTH +YLMQIMIGTKTGTNKIVEQLPKNTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVNN +STESDAVNCRMVSDISKAVWDDf +>[subseq from] class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI0009A2356D +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMGGD--------------------------------------------------- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. KC345 TaxID=2530371 RepID=A0A4R4S6U0_9ACTN +---LNRTLQELEKSYDGRIGAMGIDLGTGRKV-GYRAGERFPFNSMFKVFACAAVLGKAR +TEPGLMDKVLRWKPADMAGNSPETTEYTDTGMTPAQLCRAGITKSDGFAGNTLLKQIGGP +RGLTEFFRATGDRTSRLDRPEPWLTEWEPGEVRDTTTPAAAARTFTELTTGETLHHRDRT +RLVGWLKASLTGATRIRAGLPKDWTVGDKTGTGGHGTANDVAIVWVPGSAPMILSVFTNR +NADDTAHDDKVIASTATALAK-- +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium piscicola TaxID=1378299 RepID=A0A1T5HYY1_9GAMM +--NLEQYLRDTEQQIQGQIGVAVIDTQNNTQW-NFNGSERFPMMSVFKTLACANVLYDVQ +QNTLSLTQKIDVTKAGLINWNPITQNFVGGQMSLQSVCGAAMLMSDNYAANLALELIGGP +QGLTTFLRTIGDNNTRLDHFEPKLNYVEKGAKNDTTTPIAMMNTVKKLLIGNVLNAENKA +QLQLWMTNNMVSDGLARAVLPQGWNIADRSGGGVNGSRTLTAMVWNKDHQPVFIGIFIAN +SKKTLPELNKVMVAISEKIFHQy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A2Z6A9S2_SHIFL +------------------------------------------MMSTLKVLLCDAVLSRVD +AEQEQLARRIHYSQNDLVEPSPVTEKHLTDGMTVREPCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDNVNRLDRWGPELNEAIPNDERDTTMPAAMETTLSKLLTGELLTLASRQ +QSIDWMEADTVAGPLLRSALPAGWFIADKSGAGERGSRGIMAALGPDGKPSRIGVIYTTG +SQATKDERNRQIAEKGALL---- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacterium sandarakinum TaxID=629680 RepID=A0A1H1V5Z8_9MICO +----TAELKGIEGEYDARVGVHAVDTGDGSTI-EHRSDERFGFASTIKSLAVAELLATTS +--PDDLDEQVTWSKEDVDKYAPVTKKHLGDGLPLEKVAEAAIRVSDNAAANIVFDHIGGP +QGLDTALEDLGDPVTEVVDREPELNVIDHDSTDNTTTPAAFSSDLTALLDPEHLSDEDRK +VLLEWMSGNATGDPLIRAGAPDGWKVADKSGHSD-ALRNDVAIVFPPERDPIIIAIMTEH +HDPNSKSDAALIEDTARAVLGEf +>[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=A0A0E3YZD1_9GAMM +--------RTLEVG-PARLGVCFLDTATGEAS-GNRIEEYFALCSTFKLALVSAYLREAD +QGRINLDEVLVYTEADLLPWAPVTRKNLAKGLSIAELAQAAQEMSDGAAANLLVRRLGGP +AAVTAKIREMGDIVTRLDRYEPDLGLVLSADLRDTTSPLAMAQLVRRITTGDILQRGSRE +RLLHWMQNTKTGFNRLRAGLPAEWRSGNKTGTGRTNKCNDIAITFPPSRSPIIIATYFDS +GEQTEARHEAVLAEVGRIAAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBA15_013 TaxID=1898739 RepID=UPI0008DCC051 +--AVARTLADLEREYDATVGVVATDTTTGETV-AYNGDRRFGYASTLKAFAAAQFLRAVH +--GADRDERVRWSAADATAHSPVTSAHVADGLTVAQLAEAAVRQSDNLALNLVLDRIGGP +AGLDRALAELGDRTTEVVHDEPALNTIEPGSTEDTTTPAAFAATLATVLDGQTLGRSDTA +LLEHWMSGNATGDTLVRAGAPEGWTVVDKSGGAG-GIRNDVARVTRPDGGPIVIAVLTTR +NAPDTAYDDALVARSAAAVLDAf +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=uncultured soil bacterium TaxID=164851 RepID=M4Q6F4_9BACT +------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEG---------------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. J1-007 TaxID=2661913 RepID=UPI001326EBF1 +---LNDTLRKLEKSYHGRIGAVGIDLGTGKTV-GYRAGERFPFNSMFKVFACSAVLHKAR +TSPGLMDKVVHWTPGEMAENSPETTEYTDTGMTPAQLCRAGITKSDGFAGNQLLKQIGGP +PGLTAFFRSLGDRVSRLDRPEPRLTEWEPGDERDTTTPAAAARTFAELTAGTGLHPSDRA +RVVAWLKASLTGATRIRAGLPKDWTVGDKTGTGGHGTANDIAIVWPPRSAPLILSVLTNR +ATDGVPHDDKVIASTATALAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium epidermidis TaxID=1698 RepID=UPI000785456C +-qKVEDQLKKLEARYDARVGVSAVDTESGESV-DHRADERFGFASSLKVFAVAELLDRTT +--PKELEKNVTWTQADVDEWTPVTEEHVDDGLPLEDVAESGLRVSDNLAMNIVLDELGGP +EALDDAMEKDGDSTTEVTDEEPELNDVEEGDTDNTTTPAAFTANLQDLLDAKRLSDDDRK +VLFDWMSANETGDPLIRAGAPDGWVVRDKSGHSD-AIQNDIAVVTPPDRKPIVLSVMTET +DDPESEDGPALVAAVAEVVLNEf +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium sp. NCIMB 13483 TaxID=2022103 RepID=UPI000D1601F4 +--NLEQYLRDTEQQIQGQIGVAVIDTQNNTQW-NFNGSERFPMMSVFKTLACANVLYDVQ +QNTLSLTQKIDVTKAGLINWNPITQNFVGGQMSLQSVCGAAMLMSDNYAANLALELIGGP +QGLTTFLRTIGDNNTRLDHFEPKLNYVEKGAKNDTTTPIAMMNTVKKLLIGNVLNAENKA +QLQLWMTNNMVSDGLARAVLPQGWNIADRSGGGVNGSRTLTAMVWNKDHQPVFIGIFIAN +SKKTLPELNKVMVAISEKIFHKy +>[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium marinum TaxID=418643 RepID=UPI001438B5E1 +--EVTADLTSIEDEYDARVGVHAMDTGDGSFV-EHRSDERFGFASTIKSLAVAELLDTTS +--AEQLDEQVTWTEDDVEDYAPVTKKHLGDGLPLEKVAEAAIRVSDNAAANIVFDHIDGP +AGLDSALEDLGDPTTEVIDREPELNVIDHDSTDNTTTPAAFSGDLAALLDSENLSADDRE +LLIDWMSGNATGDPLIRAGAPEGWEVADKSGHAD-ALRNDVAIVFPPKRDPIVIAIMTEH +HDPNSESDAALIEDTARAVLSAf +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI001299529A +--ATTQDLKKVEDKYDANIGVYALNTVTDGEI-TFNEDKRFAYASTFKALSSAMLLEKTP +--HNKLNKKVHVSKEDIVPYSPVLEKFINKDISIKKLIEATMLYSDNTANNMIIEELGGY +KEVNKRLKSLDDKTTKPSRMEPELNNYNPKSNRDTSTPQAFGKTLNKLINDGRLSKENKT +FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSETAKVVLEKf +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1A3 TaxID=2080521 RepID=UPI000CE8EF32 +---VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVRSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A519HPN3_9CAUL +-------LSALERANGGRLGFVAHDVGSGRRL-AWRGDERFVYCSTFKMYLAAATFLRVQ +AGDERLDRMIPVTAADMINHAPVTEPAIGGALSVEALMKGTVEVSDNPAANLLLKALGGL +EAMQAFYRSLGDDSTTVNRFEPTMNRL--DGDKDTITPSRSAANLKRLLVDTPLSAQHKA +TLLRWMTDTPTGPGRIKAGLPAGWTTAHKTGTGGYGPTNDIGVLYPPTGAPVIVAAYYHA +ATEPADRNEAVIAAASRQA---- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCBA15_009 TaxID=1898737 RepID=A0A1S2HWG2_9MICO +--RVDRALAALEQRYDATVGVVATDTGTGATV-SYRADRRFGYASTIKVLAAAAFLRSVP +--VAERSAVVHWTAADVAAYSPVTEQHVADGLPSDEVAEAAVRMSDNTALNVLLDRIGGP +AALDAALADLGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFAAVLARVLDGRTLGRADTA +LLTDWMSGNATGDALVRAGAPDGRVVADKSGGAGP-IRNDVARVTRPDGDPVVIAVLTTR +NDPDEPYDDALVAESARVAL--- +>[subseq from] Beta-lactamase n=2 Tax=Brevibacterium linens TaxID=1703 RepID=A0A0B9ANZ6_BRELN +hqRLEKQLKKLEDRYDARVGVSAFDTESGESV-DHRADERFGFASSLKAFAVAELLDRTT +--PKELEKNVTWTQADVDEWTPVTDKHVDDGLPLEDVAESALRVSDNLAMNIVLDELGGP +EALDDAMEKDGDTTTEVTDEEPELNDVEEGSTDNTTTPAAFTANLQGLLDAKRLSDDDRK +VLFDWMSANETGDPLIRAGAPEGWVVRDKSGHSD-AIQNDIAMVTPPDRKPIVLSVMTET +DDPESEDGPAMVAAAAEAVLTEf +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. YR583 TaxID=1881047 RepID=A0A1H6GC83_9SPHN +----AKAIRDLERRSGGRLGIAVVD-GGGRLVsAGRGHERFAMCSTFKLLLAGQLLERAA +-KGVSLRTPLAFTRADLVSYSPGTERLLGPDQRLGLAARDAVVLSDNTAANLILTQIGGP +SAFTAALRRAGDSVTRLDRNEPELNENALGDERDTTSPIAMATSAASYVYGNRLQPEYRK +QLRGWMIESQTGLKRIRAGLPQGWIAGDKTGSCGN-AYNDVAFVETPGGRKYVIAVYLDR +PAVKGDAASAIIAEATRITV--- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter sp. CIP 110321 TaxID=1217699 RepID=R9B5T3_9GAMM +----EGQIKTL-SEKGWQIGVSILDMD-DKLI-SINGDKRFPLDSTVKALACANVLAKVD +AKKLTLDHSKTIQQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP +VGLTSFMRSIGDEVTRSDRYEPDLVINPEDDIRDTTTPNAMNASMKKLLMGNVLSKSSKE +QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGLTSMVWSETHAPVFISIYVRK +SETSLDERSEVIKLLSDHIVK-- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=UPI000D153AA1 +------LLRQTEQQIDGKIGVAVFDTQTNTSW-NFNGNKRFPMMSAFKTLACANVLYDVQ +QHKLSLTNKIKVTKAGLINWNPVTQNFVGGQMSLNSVCGAAMLMSDNYAANLALEQVGGP +QGVTKFLRMIGDKTTRLDHFEPKLNYVEKGAENDTTTPIAMMNTIKKLLTGNVLDSENKA +QLKFWMTNNMVSDGLARAVLPTGWKIADRSGGGVNGSRTLTAMVWNKHHQPLFIGIFISN +SRETLPELNQVVASISAKIFNKy +>[subseq from] Beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=A0A1Q4P568_SERMA +--TLQDQVKQYEKE-GWKVGLSILS-SDGKTI-SINGNQRFPLDSTVKSIACANVLAKVD +AKKLSLNHSMIVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAISSGGGP +EALTAFMRAIGDTVTRSDRYEPELTVNPVNDLRDTTTPDAMSKSIKKILTGEVLSDSSKA +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK +ADTSLDERSEVIRTLGSHIFDEy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1U7AE41_9BACT +-----DTVGQLETEVGGRIGVVLRHTGSDWAV-EHREDERFPMASTFKALLCGAVLSRVD +RGEESLDDLVTYKATELVSYSPVTKNHVASGMSVGQLCEATVTMSDNSAANLLLKRVDGP +EGLTRFLRGLGDRVTRLDRNEPAMNEARRGDPRDTTSPSAVLKTLDRLLFEGVLLPSSRA +QLQQWMVDDKVADVLIRKHLPKGWRIADK------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1B5 TaxID=2080530 RepID=UPI000CE90FDA +---VSAELAALESEFDARIGVSAVDTGSGRRI-EHRSNERFGYASSLKALAVAEFLRTAP +--AAERDEVVTWTAADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRIGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIEDTTTPAAFTADLAAVATGEVLSAEDRA +LLLAWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILTAR +NDPKADYDDALVARAAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000CE88DD4 +---VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAESAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter gyllenbergii NIPH 230 TaxID=1217658 RepID=V2WAG0_9GAMM +----EGQIKTL-SEKGWQIGVSILDMD-DKLI-SINGDKRFPLDSTVKALACANVLAKVD +AKKLTLDYSKTIQQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP +VGLTSFMRSIGDEVTRSDRYEPDLVINPEDDIRDTTTPNAMNASMKKLLTGNVLSKSSKE +QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGLTSMVWSETHAPVFISIYVRK +SETSLVERSEVIKLLSDHIVKEy +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A3C0W3U9_9CAUL +------DLSALEARHGGRLGVSVLT--EGKRA-DWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRAIPVTQADMISHAPVTQPAVGSTLTIAQLMKGAVEVSDNPAANILIREMGGL +DALRAFYRGIGDETTRVDRLEPELNRA--DGDKDTITPNQSVRNIERLILSEALESAFKR +LLLEWMVASPTGQARLKAGVPSGWTVAHKTGTGGDGPVNDIGVLYPTDGQAIAIAVYFHA +TKSTDAQREAVVADATRQALK-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000CD1C350 +-----------EKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVS +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus halophilus TaxID=226505 RepID=A0A1N6H3X3_9BACT +-qQISQKIERLSEKLAGRIGVAAQEIGSKEMI-TINGDEQFVMASTYKVAIAVALLDRVD +KGELKLSDLIDVEQETMVTGDGAIANHPGIKLSVANLIEPMITLSDNTATDACLKLAGGP +EAVTKMMRSIGITDLRVDRYTSEILRFEQEDPRDQSSPNAMLQLLLAIDSGKALSAESTQ +FLLSTMSRTRTGAARLKGLLPKGTPVAHKTGTIG-GVANDVGYVTLPDGRRFAIVVFTKN +STTSEADRDRAIAEVTRTLYDFy +>[subseq from] Beta-lactamase L2 n=1 Tax=Sphingomonas sp. 8AM TaxID=2653170 RepID=A0A654CG91_9SPHN +--STEDALAALERRAGGRLGVCIVDTARGTTT-GWRQDERFTQASSFKLSLAAMILAEAD +GGRLGLGERLGWSAGDILPHSPITAASAAMTLPIRELARAAVVTSDNIAANVLLRKIGGP +ARLTAFWRAIGDRISRLDRYEPALNVTPPGTVLDTTTPAAMAATVSRIVRGDVLRPASRA +LLVEWMVAADTGRNRLRAGFPAGWHAGDKTGTGGRPIYVDLAFGGPRGRAPLIVAVYYKP +VGASAAGAEAVLAAVGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. AAP58 TaxID=1523422 RepID=A0A0N1LJH5_9CAUL +-------LSTLEAREGGRLGFAAKDMGTGRVL-AWRGDERFVYCSTFKMFLAAATLLRVQ +AGEERLERMIPVTRADMVSHAPVTEPAIGSSLSVEALMKGTVEVSDNPAANLLLKAMGGL +EPMQAFYRDLGDATTRVDRFEPEMNRL--DGDKDTILPLQSVANIQRLLVDTPLSADHKA +LLLKWMIDTPTGMARIKAGVPTGWTVAHKTGTGGYGPTNDIGVLYPPSGAPVIVAAYYHA +AS-DDPKNEGVIAEATRLAL--- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Mucilaginibacter ginsenosidivorans TaxID=398053 RepID=A0A5B8UWT6_9SPHI +-kELLSRIKTISAESKGIVGVSILGLESHDTL-NYNGQSRLVMHSVFKFPIAMAVLNLVD +KGKYKLDKKMKVGKGDMHPWSPMRDKYPDGALPLSEIIGYMVSQSDNTACDFLLKKIGGP +KVVEEYIHSLGVKGIAIKASEADMASAWEVQYTNWAKPADLVYLLDIFYHGKALSKQSND +FLMQAMLATTTGPHRLRGLLPKDAVIAHKTGTSPTNATNDIGIITLPNGKHLAIVVMVCN +SKADEATRDAVIAKIAKAAWDTy +>[subseq from] Beta-lactamase n=1 Tax=Subtercola boreus TaxID=120213 RepID=A0A3E0VE13_9MICO +-------FEKLERQYDARVGVSAIDTATGRQV-NYRAEERFGYASTLKVFVAAEFLHDVS +--ASDRDGRVKWSESDVQAYSPVTSENIETGLTLSQLAEAAVRKSDNTAVNLLIAQLGGP +QAIDAGLTELGDSQSEVVNDEPLLNRIEPGSTDDTTTPATFRANLTSLIEGSYLEPADLA +ILTGWMSGNTTGSALIRAGAPSGWTVADKSGGAG-GIRNDIAVVTPPGRDPIILSIFTNT +LDPAAAYDDRLVAEASAAVFDE- +>[subseq from] Beta-lactamase n=2 Tax=Brevundimonas diminuta TaxID=293 RepID=L1QQB0_BREDI +------DLSALEARHGGRLGVSVLT--EGKRA-DWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRAIPVTQADMIAHAPVTQPAVGSTLTIAQLMKGAVEVSDNPAANILIREMGGL +DALRAFYRGIGDETTRVDRLEPELNRA--DGDKDTITPNQSVRNIERLILSEALESAFKR +LLLEWMMASPTGLARLKAGVPSGWTVAHKTGTGGDGPVNDIGVLYPTDGAPIAIAVYFHA +TKSTDAQREAAVADATRQALK-- +>[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas sp. AAP58 TaxID=1523422 RepID=UPI0006B88934 +-------LSTLEAREGGRLGFAAKDMGTGRVL-AWRGDERFVYCSTFKMFLAAATLLRVQ +AGEERLERMIPVTRADMVSHAPVTEPAIGSSLSVEALMKGTVEVSDNPAANLLLKAMGGL +EPMQAFYRDLGDATTRVDRFEPEMNRL--DGDKDTILPLQSVANIQRLLVDTPLSADHKA +LLLKWMIDTPTGMARIKAGVPTGWTVAHKTGTGGYGPTNDIGVLYPPSGAPVIVAAYYHA +AS-DDPKNEGVIAEATRLAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=UPI00114F9A26 +--TLQDQVKQYEKE-GWKVGVSILS-SDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD +AKKLSLNHSMVVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP +EALTEFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDASKA +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK +ADTSLDERSAVIRTLGSHIFDEy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059Q5E9_9BACT +--TVTEAAMAVEADLGGRVGTLLRAPGAAPLA-AWQADDRFPLSSTFKAPLCGAVLARVD +AGSEQMDRVIPYTAQDLVSHSPVTETRAGKGMRVADLCAATITLSDNTAANLLLDTVGGP +EGFTGFLRSIGDMTTRLDRQETALNEALPKDQRDTTTPRAMTDTLEALLFSGILSTESRT +QLESWMQQDQVAGALIRASLPEGWTIADKTGAGGHGARSIV------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis panaciterrae TaxID=363841 RepID=UPI00141FAD5A +-----KALSDLEKRSGGRLGIAVVDARGKLVM-ADRGHERFAMCSTFKLLLAGQMFERAA +-KGSSLGTRLAFTRADLISYSPGTEKLIGPDQRLELAARDAVVLSDNTAANLILKQAGGP +AAFTAALRRAGDKVTRLDRIEPELNENALGDERDTTSPIAMATSAASYVFGNRLRPAYRE +QLRGWMIESRTGLNRIRAGLPQGWMAGDKTGTCGN-AYNDVAFAEAPDGRKYVIAVYLDR +PTVAGDAANAVIAEATRLTVE-- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X756_9BACT +------------------------------------------MCSTFKALAAALVLVRVD +EGEEKLDRRIKFSKKELVSGSPVTQARVGEPMTVAELCDAAVTRSDNTAGNLLLASFKGP +AALTAFCRTLGDDVSRLDRIETELNYDRSDDIRDTTTAAVMLENLRKLLFTDILSGGSRS +QLVAWLITSKTGDARLRAGLPKSWLVGDKTGTNGYGNANDIAVIWPPDRAPIIVTAYCEI +PSIPADERDAVIADIGRIAS--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=D2XSF3_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAEXXXXXXXXXXXXXXXXXXXXXXXX +XSVTAFALQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILV----- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1C1 TaxID=2080534 RepID=UPI000CE7F01D +---VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDSTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. OK281 TaxID=1881067 RepID=A0A1I5CEG6_9SPHN +-------IAAIERKHGGRLGVFVLDTGSGRTL-AHRAEERFLMCSSFKGVLAACVLARID +AGIDRLDSMIHYGRSDLLTSSPVTEAHVEVGMSVEALCGAILTQSDNAAANLLLARINGP +AALTKFARRLGDRTTRFDRTELDLNTA--SGLLDTTTPAAIVSTVRMIYLGRVLKPTTLT +VLERGMIANARGPRRLRGTLPRSWIVGDRTGTSDD-YCNDLAFARRPHAAPVVMAAYYEA +PGRTTEAREAVLREVGTRIAD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter frigoritolerans TaxID=652788 RepID=A0A562UGK9_9SPHI +-tSLHDQVEQIAKPAKAIVGVSILNLETGDTV-NYNSKARLVMHSVMKFPIALTVLHLVD +SGTLKLDQMIHVTKKDMQKYSPLRDKYPKGDVSVSDLLGYMVSQSDNDACDILLRVLNGP +QTVQDFMLRSGIRGIAVRASEADMASAWELQYTNWCKPVEMNLLLDKFYTGKLLSKSSTD +FLYKLMVATTTGPKRIKGLLPEGTVVAHKTGTSPTSATNDVGIIELPNGKHLIVSIFVCN +SKDDEATRETVIAKIAKAAYDYy +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas naejangsanensis TaxID=588932 RepID=A0A4P7BSZ4_9CAUL +------DLSALEARHGGRLGVSVLT--EGKRA-DWRGDERFLYCSTFKMYLAAATLLRVQ +AGQERLDRAIPVTQADMIAHAPVTAPAVGSTLTIEQLMKGAVEVSDNPAANILIREMGGL +DALRAFYRGIGDETTRVDRLEPELNRA--DGDKDTIQPVQSARNIERLILSEALESASKR +LLLEWMVASPTGQARLEAGVPSGWTVAHKTGTGGGGPVNDIGVVYPIEGAPIIIAIYFHA +TPSTDAQREAVIADAARLALK-- +>[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas hominis TaxID=156981 RepID=UPI001134C1DE +---VAGDLAALEESTGRRVGVYARDTGTGATV-AYRADERFGYASTLKALAVGEVLAGRP +--ASVLDEPLTVAPDDVAGHAPVTGDAAGTDLTIAALGAAAVSESDNGALNVLLRHLGGP +AALQAALAARGDTTTRVDADEPELNAFTPGGEARTSTPRALAGGLATYALGDVLDPAVRE +TYVGWLTASTTGPDAIRAGTPDGWTVGDKTGTAGYGSRNDIAVVWPPGRQPIVLAVLTDH +PDEAAEPDDAVLAAAARSVLAAy +>[subseq from] Beta-lactamase class A n=2 Tax=Novosphingobium sp. PhB57 TaxID=2485107 RepID=A0A4R3TBT5_9SPHN +--QAASDLEEIERQHGMRIGAVMRGSDGRIHF-AHRADERFRLCSTFKIFLAAEVYRQAA +TNPHLLQRPVTIRDTDRLGNSPVTARQRDGSLSAEMLCKAAVQYSDNSAANYLLDLVGGP +PAVTRLFRTLGDNISRLDRMEPALNLGAPEDFRDTTTPAAIARSLGTLLLSTVLGDHQRA +TLLGWMRNEQNGTRRIRAGVPRGWTVANKPGTNDAGAVNDIAIIRPPSGGSFVLTVYTAS +AENRVTQSESVIAAIAGMA---- +>[subseq from] Class A beta-lactamase n=1 Tax=Frigoribacterium sp. Leaf164 TaxID=1736282 RepID=A0A0Q5L9F3_9MICO +--------AALESEHGARVGLSVVDTGTGRAL-EHRGDERFLYASSLKALAAAALLDATE +--PADLDEVVTWTADDVAAYSPATSAATGTGLTLGQLAEAAVRQSDNTALNLVVEHLGGP +AALDAALAAQGDDVTDVVHGEPELNRPTAGSTADTTTPAAVRGLLARVVAGEWLGDDDRA +QLLEWMSGNATGDALVRAGAPEGWAVADKSGGAGP-VRNDVAVVTRPGGDPVVIAVLTTR +TDPAAAYDDALVAAAARAAFE-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium palustre TaxID=493376 RepID=UPI00040D7069 +-qSLKMQIESIIKAKNATVAVSVLDFENNKSL-DINGDKKLPMLSVFKFHIALAVLNLVD +QGELNLNQKIFIKKTDLHEWSPIREKYPAGNMSLSELLKYSVAQSDNNGTDLLLKLIGGP +GEVQNFINNTGISDFRIKADEEKMHQGYEFMYWNWTTTNASNQLLKKFFEGKLVSKKSTD +FLMQTMLETSTGANKLVALLPKGTPVAHKTGSSGKDAENDIGIVTLPSGKHYAVSAFVSD +SMESDETNTKMIAEISKLIFDYf +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. A083 TaxID=1759083 RepID=A0A0W1IDK5_9SPHN +--SVANRIAALEKKSGGRLGVAVTDQFGKLIV-GHRADERFAMCSTFKLLLAAQTLTAAK +-NGVSLRTPLPFTRADLLPYSPGAERLLDAEYRIGFAAEDAVVLSDNLAANLLLDHFGGP +TAFTDHVQATGDLVTRLDRVEPELNANIPGDPRDTTSPAAMAKSAAAYIFGDKLDPAYRT +MLRDWLVKSETGLARIRAGLPRTWHVGDKTGTCGT-AYNDVAFVEEPGGDKYMIAVYLDR +PALKGDAANAIIADVARAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium sp. WO024 TaxID=2697563 RepID=UPI001423228C +hrQLDNQLKALEDRYDARVGVSAVDTADGTTV-GHRGDERFGFASTLKVFAVAELLDRTT +--PKQLKKNVTWTQDDVDEWTPVTGKHVDDGLPLTDIAEAALRVSDNAAMNIVLDEIGGP +EGLNAALENEGDATTEIVDEEPGLNVVTPGRTDNTTTPDALTADLKGLLDPRRLSTDDRD +QLLEWMSDNETGDPLIRAGAPDGWSVKDKSGHSDT-IQNDIAVVTPPGEDPIVLSVLTEA +KDPD--SGAALVAAVAEAVLDGf +>[subseq from] Beta-lactamase n=1 Tax=Dyadobacter koreensis TaxID=408657 RepID=A0A1H6TLW0_9BACT +--IFRQKIEKILPQAKGTVGVAIMGLEDRETF-LFNEGLKYPMQSVYKFPLAMAVLNQVD +KGKLSLNQKIHITSKDLLPWSPIREKYPKGNLKLSEILAYTVSQSDNNGCDILFRLIGGT +KKVDAYIHSLGIKSIAIAATEEEMHKDWNAQFANWCKPRAMLRLLEIFYKGKALSKTSND +FLWKVMTETTSGPNKIKGLLPKSASVAHKTGLSDTKATNDAGIMTLPNGEHVAIVVFVSN +TPVDEKTRDGVIAQISKAAWDYy +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. OK281 TaxID=1881067 RepID=UPI000B8849E2 +-------IAAIERKHGGRLGVFVLDTGSGRTL-AHRAEERFLMCSSFKGVLAACVLARID +AGIDRLDSMIHYGRSDLLTSSPVTEAHVEVGMSVEALCGAILTQSDNAAANLLLARINGP +AALTKFARRLGDRTTRFDRTELDLNTA--SGLLDTTTPAAIVSTVRMIYLGRVLKPTTLT +VLERGMIANARGPRRLRGTLPRSWIVGDRTGTSDD-YCNDLAFARRPHAAPVVMAAYYEA +PGRTTEAREAVLREVGTRIAD-- +>[subseq from] Beta-lactamase n=1 Tax=Actinocorallia herbida TaxID=58109 RepID=A0A3N1CU24_9ACTN +--AARKALRALEREYDARLGVWALDTGTGDFV-DFNADERFAFASTFKPLVCGVLLQQAS +--DRRLAAVVRWKAADVVANSPVTARRTARGMTLAQLCEAAIRHSDNTAINLVLAEIGGP +KAFTDALHDLGDTATRSDRIEPAMSDVPPGETRDTTTPRAFATDLGAFLLGDALPDPRRA +LLADWLSRPLPLSAEIRGGLPDGWRVHGKTGTTANGGRNYIAVTHPPGRAPLLLAVLSTR +TDPSLPTDDTLLATA-------- +>[subseq from] class A beta-lactamase n=1 Tax=Actinocorallia herbida TaxID=58109 RepID=UPI000F4C83B0 +--AARKALRALEREYDARLGVWALDTGTGDFV-DFNADERFAFASTFKPLVCGVLLQQAS +--DRRLAAVVRWKAADVVANSPVTARRTARGMTLAQLCEAAIRHSDNTAINLVLAEIGGP +KAFTDALHDLGDTATRSDRIEPAMSDVPPGETRDTTTPRAFATDLGAFLLGDALPDPRRA +LLADWLSRPLPLSAEIRGGLPDGWRVHGKTGTTANGGRNYIAVTHPPGRAPLLLAVLSTR +TDPSLPTDDTLLATA-------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A2Z6A9F1_SHIFL +------------------------------------------MMSTFKVLLCGAVLSRVD +AGQEQLGRLKLDSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMTDNTAAFLLLTTIGGP +MFRTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEHGSRGIIAELGPDGKPSRIVVIYTTL +SQATMDVRNRQIALIGASL---- +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Escherichia coli TaxID=562 RepID=A0A345N899_ECOLX +-------------------------------------------------MAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLILV----- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium oranimense TaxID=421058 RepID=A0A1M5JYB2_9FLAO +-sALEQKINSITKGKKATVGVSVLGFENNFKF-SKNGDKPLPTLSVFKFHIACAVLDLVD +QGKLSLDQKIFFKKEDILEWSPIREKYPEANLSLGEVLDYTVALSDNNGCDMLLRLIGGT +ETVQKFMDSKGVKGFQIKHNEDDMHKNWKTQYENYSTPNSAVLLLKKFYDGKLLSKKSTD +YLMQIMIGTKTGTNKIVEQLPKNTPVAHKTGSSGNGAENDMGIITLPDGKHYAIAVFVNN +STETDEVNCRMVSDISKAVWDDf +>[subseq from] class A beta-lactamase n=1 Tax=Agromyces salentinus TaxID=269421 RepID=UPI0012F8F3A7 +--RMSRELRALEAATSVRIGVHAVAQGGRRAF-RYRGDELFPMCSLFKPLAAAALVQARG +YDEAYWTTPIPFTDADLVVDSNVLDKLDPQEATPGELADAALRFSDNTAGNLILRELGGP +AAVTAFAASLGATDTRLDRWEPDLNQAIPGDERDTTTPDDIAHLYSALLLDEAAGLLAAS +QLRAWMLRNRTSDARMRAGLTPPYDLADKTGGGAYGVVNDAGVLWRPDAAPLTLAILTST +DRADAVRNNAVVAEATRIVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Polyangium spumosum TaxID=889282 RepID=UPI00129A93C9 +--RLERDIAAAEARSGGRLGVAVVEPTSGERW-VHHAGQRFPLQSTFKAPLAAAVLARVD +AGALSLDTKIEVRRDDLSVWSPLAESFQGEAFSVLDLITESVTTSDNTAADVLMHQLGGP +ESVNVLLSKSAVVGIRVDRYERDLQLAYLRDPRDTTTPEAAADFLLKLDRGEMLGPTSTR +VLLDIMYATKTGAQRLRAGLPPGARLAHKTGTSANGATNDIGIATLPDGRKLVIVALLTD +SNAPQETREAALADVARAAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Curtobacterium sp. PhB115 TaxID=2485173 RepID=A0A3N1K9Y7_9MICO +--AVRRAISSLEREYDATIGVVAVDTATGATV-THNGDRRFGYASSIKVFAAAQFLRTVR +--GDARDEVVHWTADDVAAYSPVTEQHVADGLSYAQLAEAAVRMSDNTALNLVLTRIGGP +NGLDTALADLGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTSALATVLDGTTLSTADTA +LLVSWMSGNATGDALIRAGAPDGWVVADKSGGAGP-IRNDVARVTRPDGDTIVLAVLTRR +DDPAQPYDDALVARSAAAVLRAf +>[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus boseongensis TaxID=1442587 RepID=A0A4R6T768_9BACT +-qQISQKIERLSEKLAGRIGVAAQEIGSKEMI-TINGDEQFVMASTYKVAIAVALLDRVD +KGELKLSDLIDVEQETMVTGDGAIANHPGIKLSVANLIEPMITLSDNTATDACLKLAGGP +EAVTKMMRSIGITDLRVDRYTSEILRFEQEDPRDQSSPNAMLQLLLAIDSGKALSAESTQ +FLLSTMSRTRTGAARLKGLLPKGTPVAHKTGTIG-GVANDVGYVTLPDGRRFAIVVFTKS +STTSEADRDRAIAEVTRTLYDFy +>[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium epidermidis TaxID=1698 RepID=UPI000BF69A05 +hqRLEKQLKKLEDRYDARVGVSAFDTESGESV-DHRADERFGFASSLKAFAVAELLDRTT +--PKELEKNVTWTQADVDEWTPVTDKHVDDGLPLEDVAESALRVSDNLAMNIVLDELGGP +EALDDAMEKDGDTTTEVTDEEPELNDVEEGSTDNTTTPAAFTADLQGLLDPQRLSDDDRK +VLFDWMSGNETGDPLIRAGAPEDWVVRDKSGHSD-AIQNDIAMVTPPDRKPIVLSVMTET +DDPESEDGPAMVAAAAEAVLNEf +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI00066CC709 +--ATTEDLKKIEDKYDANVSVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP +--HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY +KEVNKRLKSLDDKTTKPSRMEPELNNYDPKNNRDTSTPQAFGKTLNKLINDGRLSKENKT +FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVISETAKVV---- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium iliopiscarium TaxID=56192 RepID=UPI000D166F47 +--DIDQYLRDTEQQIQGQIGVAVIDTQNNTQW-NFNGSERFPMMSVFKTLACANVLYDVQ +HKALKLTDKIDVTKAGLINWNPITQNFVGGKMSLQSVCGAAMLMSDNYAANLALEKIGGP +QGLTAFLRTIGDNSTRLDHFEPKLNYVEKGAKNDTTTPIAMMNTVKKLLIGNVLNAENKA +QLQFWMTNNMVSDGLARAVLPQGWKIADRSGGGVNGSRTLTAMVWNKDHQPVFIGIFIAN +SKKTLPELNKVMVAISEKIFHQy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=L0HTV3_ECOLX +-----------------------------SQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIAGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGY------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium angstadtii TaxID=558151 RepID=A0A0J7IE39_9FLAO +-sALAQKIDAITKGKKATVGVSVLGFENNVKY-NKNGDRPYPTLSVFKFHIACAVLDLVD +QGKLSLDQKLFFKKEDMLEWSPIREKYPDANLSLGEVLDYTVALSDNNGCDLLLKLIGGT +QTVQKFMDSKGVKGFQIKRNEDDMHKNWKTQYDNYSTPNSAVHVLKKFYDGKLLSKKSTD +YLMQIMIGTKTGTNKIVEQLPKNTPVAHKTGSSGNGAENDMGIITLPNGKHYAIAVFVSN +STETDAVNCKMVSDISKAVWDDf +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas naejangsanensis TaxID=588932 RepID=A0A494RLD3_9CAUL +------DLSALEARHGGRLGVAVAT--EGKRA-AWRGDERFVYCSTFKMYLAAATLLRVQ +SGLERLDRAIPITAADMVSHAPVTQPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL +EPFRAFYRGLGDTITRVDRLEPEMNRL--DGDKDTITPDQSTRNIERLLVDTPLSPASKT +LLMRWMTETPTGQGRIRAGVPVGWTVAHKTGTGGYGPVNDIGLILPPTGAPIVLAVYFHA +TASTDAQREAVIAEATRQALK-- +>[subseq from] Beta-lactamase n=2 Tax=Curtobacterium sp. UNCCL20 TaxID=1502773 RepID=A0A1H0ZCL2_9MICO +---VAAALARLEQQYDATIGVVATDTRTGESV-TYNGDRRFGYASTMKVFAAAEFLRSVH +--GAARDEVAHWTAADTTAHSPVTEQHLADGLTYARLAEAAVRDSDNTALNLVLERIGGP +SALDAALADLGDDTTRVVHDEPALNTIEPGSTEDTTTPAAFTADLTKVLDGSTLGTADTA +LLVDWMSGNATGDTLVRAGAPAGWVVVDKSGGAG-GIRNDVARVTPPDGDPIVLSVLTAR +NDPGAAYDDALVAKTASVVLGAf +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI000E6892DE +--ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKALSSAMLLEKTP +--HNELNKKVHVSKEDIVPYSPVLEKFINKDISIKKLIEATMLYSDNTANNMIIEELDGY +KEVNKRLKSLDDKTTKPSRMEPELNNYNPKSNRDTSTPQAFGKTLNKLINDGRLSKENKT +FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSETAKVVLEIf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. legu1 TaxID=2602768 RepID=A0A5C7FCW2_9FLAO +-qNLNKEIQKIVEGKKATVAVSVLDFGNNQSV-DLNGDQKLPMQSVFKFHIALAVLDYVD +EGKLKLEQKIFIKKSDLLEWSPIRNKYPDGNLPLSEIIRYTVAESDNNGCDLLLRLIGGT +ETVQNFMNSKGIKNFSITANEEEMHKDWKVQYRNFTTTNSMNELLKKFSEGKIVSEKSTA +FLIKTMLGTTTGTNKIAGQLPKNTPVAHKTGSSGTGAENDAAIITLPNSKKYALTVFVSD +SMESETENCKIISDISRKVWEY- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A556C4Z2_9MICO +-eKVSSELESLEEDFEARIGVSAVDTGDGTSV-DYRSDERFGFASTLKVFAVAELLARTT +--SADLDEQVTWTQADVDEWTPVTEKHVDTGLPLRDVAESALRVSDNAAMNIVLDEIGGP +QGLDAALEDAGGPTTEVIDEEPELNDVDPDSSDNTTTPKAYTADLQGLLDSDRLPEDDRE +VLLEWMSDNETGDPLIRAGAPEGWTVKDKSGHSD-GIQNDIAVVYPPNEDPIIITVLTQS +EDPDSEDGPALVAATAEAVFDSf +>[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia fungorum TaxID=134537 RepID=A0A2N8QQB7_9BURK +--AAESPLADIERRRGGRLGVFAIDTGSGRTL-CHRADERFLMCSTFKGLLAAQILARID +SGAERLDRLVHYTQKDLIFTSPVTKTNVARGLSIDALYRAVLVESDNTAAILLMRSAGGP +AALTRFVRGLGDTVTRSDRYEPDSNRY--RGVLDTTTPKGIATTAQRLLLADVLSAGSRA +QLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDSETNDYALVRPPGRAPLLVAVYYDA +PAIGMDARESVLREAGTAFV--- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas naejangsanensis TaxID=588932 RepID=A0A172Y9C4_9CAUL +------DLSALEARHGGRLGVSVLT--EGKRA-DWRGDERFLYCSTFKMYLAAATLLRVQ +AGQERLDRAIPVTQADMIAHAPVTAPAVGSTLTIEQLMKGAVEVSDNPAANILIREMGGL +DALRAFYRGIGDETTRVDRLEPELNRA--DGDKDTIQPAQSARNIERLILSEALESASKR +LLLEWMVASPTGQARLKAGVPSGWTVANKTGTGGGGPVNDIGVVYPIEGAPIIMAVYFHA +TPSTDAQREAVIADAARLALK-- +>[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas fluminis TaxID=2487274 RepID=UPI000F65746F +-------LSALEARDGGRLGFVAQDLDSGRLL-AWRGDERFVYCSTFKMFLAAATFLRVQ +AGEERLDRMIPVTRADMVNHAPVTEPAIGDALSVEALMKGTVEVSDNPAANLLLKANGGI +DAMRAFYRGIGDADTTVDRYEPEMNRL--DGDKDTIKPLSSAANLKRLLIGDPLSAPHKE +KLLRWMIDTPTGQARIKAGVPAGWTVAHKTGTGGYGPTNDIGVLYPPTGAPVIVAAYNHG +AGEAAPEREAVIAEATRLAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas naejangsanensis TaxID=588932 RepID=UPI0013C53894 +------DLSALEARHGGRLGVAVAT--EGKRA-AWRGDERFVYCSTFKMYLAAATLLRVQ +SGLERLDRAIPITAADMVSHAPVTQPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL +EPFRAFYRGLGDTITRVDRLEPEMNRL--DGDKDTITPDQSTRNIERLLVDTPLSPASKT +LLMRWMTETPTGQGRIRAGVPVGWTVAHKTGTGGYGPVNDIGLILPPTGAPIVLAVYFHA +TASTDAQREAVIAEATRQALK-- +>[subseq from] class A beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=UPI0011E8D936 +------------------------------------------------------------ +---------AHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas subvibrioides TaxID=74313 RepID=A0A258HFY0_9CAUL +-------LSGLEQAHGGRFGLFAHDLGTGRQL-TARGDERFVYCSTFKMYLAAATLLRVQ +AGDEQLDRLIPVTRADMVNHAPVTEPAMGSSLTVERLIQAVVEVSDNPAANLLLKALGGI +APMQAFYRGIGDASTRVDRFEPEMNRL--DGDKDTITPAQSAANIHRLFIDPALSQDSKT +MLLGWMFSSPTGVDRIKAGVPADWRVAHKTGTGGYGPTNDIGILYPPIGEPIIVAAYYHA +AS-DRPGNEAVIAEATRLAL--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000CE73834 +---VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDSTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRSGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=G8EI98_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQ------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis terrae subsp. ummariensis TaxID=429001 RepID=A0A1Y6FTJ6_9SPHN +--SAANRIDALEKKSGGRLGVAVTDQFGKLIV-GHRADERFAMCSTFKLLLAAQTLTAAK +-SGVSLRTPLPFTRADLLPYSPGAERLLDAEYRIGFAAEDAVVLSDNLAANLLLDHFGGP +TGFTDHVQATGDLVTRLDRMEPDLNANIPGDPRDTTSPAAMAKSAAAYIFGDKLDPAYRA +MLRDWLVKSETGLTRIRAGLPRTWHVGDKTGTCGT-AYNDVAFVEEPGGDKYMIAVYLDR +PALKGDAANAIIADVARAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Chitinophaga pinensis TaxID=79329 RepID=UPI001157695B +-----QNIATIATESGGTVGVAIRNLHTGDTL-TLNDTARLPMQSAYKFPIAMAVLKQVD +EGKLRLDQTIPVTTADLFKYSPLQDSFPKGTQTVADLIRLMVAKSDNIACDVLLKTIGGT +KVANDYIHSLGVQNISIAATEQEMHSGWDVQFTNWCNVSAYTQLLDILYKGTALSKSSND +FLMQTMLGTTTGPKRLPGLLPAGTPVAHKTGTSGYSATNDAGIITLPNGQPLAVVVFVTR +STASEAVREGVIAKIAKAAYDHy +>[subseq from] class A beta-lactamase n=1 Tax=Cellulosimicrobium cellulans TaxID=1710 RepID=UPI00130EC038 +--AVEADLAALERSTGRRVGVYAHDTGTGDTV-AYRADERFGYASTLKALAAGELLAGQP +--ASVLDRPLTVTAEDVADHAPVTAGAAGTDLTIGALGAAAVTDSDNGALNVLLRHLGGP +AALEAALAARGDTVTLVDAAEPELNRFTPGDPARTSTPRALAEGLATYALGDALDPAVRQ +AYVGWLTASTTGLDAIRAGTPEGWTVGDKTGTAGYGSRNDIAVLWPPGRAPIVLAVLTDH +PDEAAEPDDAVLAAAATTVLAAy +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. VKM Ac-2805 TaxID=2609258 RepID=UPI0013202EE6 +---VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASGLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRV +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A2D7ZHW4_9CAUL +------------RAGEARLGVAVMNLENGDLW-AINGSDRFPMQSVFKAPLGAAVLAEVD +AGRLALDEILTVKDEDLSPYSPVAAAYPGRRYTVDELLTLAVGGSDNTAADVLMARIGGP +GAVTAWLRSHDIDHMRIDRYERQLQPRYLEDPRDTTTPRDALLFLAKLARGELLSEASTA +RLLRIMEDSPSGANRLAAGLPDQARLAHKTGTARTDATNDIGLITLADGRQYVVAVFLSG +STQPEAEREAIIADTARAVTQ-- +>[subseq from] Beta-lactamase n=2 Tax=Listeria kieliensis TaxID=1621700 RepID=A0A3D8TS10_9LIST +-nSVNERLEVLENKYHAKLGVYAAN--GNEKV-KYNAQERFAYTSTYKAIISGLLLKNRT +--EEELQKKIFFSKEDLVDYSPITEKFVDKGMTLKAIIHAAVAYSDNTAGNLLLDEIGGT +KKFQEELRLIGDHTTISSRYETDLNSAVPGDLRDTTTPEAFGTDLQRLTSPKCLDPQALS +YFKQTLVDNTTGDKLIRAGVPEGYIVGDKTGAGSYGTRNDIAIIFKENGLPLVWAVFSKM +DREDAQYNDQLIADVAKVLS--- +>[subseq from] Beta-lactamase n=1 Tax=Serratia sp. S9 TaxID=2596922 RepID=A0A5C7DLF7_9GAMM +--TLQDQIKQYEKE-GWKVGLSILS-SDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD +AKKLSLNHSMVVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP +EALTEFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDASKA +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK +ADTSLDERSAVIRTLGSHIFDEy +>[subseq from] Class A beta-lactamase n=1 Tax=Corynebacterium mastitidis TaxID=161890 RepID=A0A2N0X915_9CORY +-eKIQEEFHNVEAHYGATLGVYAVDTGSGRTV-EYRPDERFAYASTMKALAAGALIDGAG +--AEGLHREVAVTAEEIVPYSPVLENHVGENVTLMEAAKAAVVHSDNTAGNKIFEALGGP +EGLQRALRDRGDAATVSCRNEPGLNEAVADQECDTTTPRAVTENLRAYLVDGILNEDERD +LLQGWMEESATGMNLIRAGLPEGWKAGDKSGMGRFGARGDTAIIFPPNGAPIVMTVYARK +DDVDSHTEDAAIADSAAVAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Steroidobacter sp. SA29-B TaxID=2695856 RepID=UPI00132AC027 +---LEAEIARLTAPIGGKVGVAAWQLDKGERI-MVNAGERFPMASTFKIAVAGAILASVD +AGRLQLDQLVAVQPNDIVPSDGIASLAIHPGLSVHNLLELMLTLSDNTATDVLTRLAGGP +QAVTAWVRKQGVEEQRIDRDTAGILRAFDKDVRDTSTPAAMGQLLTKIFNQQALSVSSTK +VLIDIMQRCHTGAGRLPGRMPAGTVIAHKTGTIG-GTVNDVGVMTLPDGSQIVIAVFIKE +SDKPMEQRERVIAEIARSVRDYf +>[subseq from] Class A beta-lactamase n=1 Tax=Siphonobacter sp. BAB-5405 TaxID=1864825 RepID=A0A2N7B9Y4_9BACT +-kSLQNQIEQLIQPKKATVGVSIYDFASKQIL-LIHGDKHLPMQSVYKFHVALAVLKEVD +KGRFKLEQKLHVKKSDLVPHSPMGEDHPNGELPLSEIIRYMVSESDGSACDYLFRLLGGP +TQVNAFIHQLGIKEVAIRETEETMQANWDVQYTNWTTPAAMLDLLKLFYQQKILSKRSHD +FLWKVMTETVTGENRLKKLLPTSTLVIHKTGTSGMGAVNDVGFIALPNGKHIAISVFVTN +TSEGIEKNEQIIADIAKLAYDHf +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis macrogoltabida TaxID=33050 RepID=A0A2W5KVQ9_SPHMC +---LSAKIAAIETRSGGRLGVAVTDADGTLRF-GHRADERFAMCSTFKLLLAGRVLSAAT +-SGVPLRSPLDFTRTDLLPHSPGAEKLLDADYRIGFAARDAVVLSDNLAANLLLDRFGGP +AGFTAFVRGMGDEVTRLDRMEPDLNENAPGDPRDTTSPAAIARSGAQLVFGDRLHQSHRA +TLRDWLVESRTGLARIRGGLPQDWVAGDKTGTCGT-AYNDVAFVEQPGGGRHMIAIYLDR +PAVSGDAANAAIAGAARAIAE-- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura madurae TaxID=1993 RepID=A0A1I5UV66_9ACTN +------RYAALEREHGARLGVFAVATGTGATV-AYRAGERFAFCSTFKTLAAAAVLHRHP +--LAHLEDRVTYTRADIDSISPITEDHVATGMTIRQLCDAAIRFSDGTAGNLLMRDIGGP +AGLTAYLRELGDGVSRMDDYEPELNRVRPGDPRDTTTPRAIAEDYRRLVLGTALPPDKRA +LIKDWLERSTTGAKRIRAGLPGGWKAAEKTGTGDYGRAN--------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Serratia nematodiphila TaxID=458197 RepID=UPI000B40BEC2 +--TLQDQVKQYEKE-GWKVGVSILS-SDDKTI-SINGNQRFPLDSTVKSIACANILAKVD +AKKLSLNHSMVVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP +EALTEFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDASKA +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK +ADTSLDERSAVIRTLGSHIFDEy +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium iliopiscarium TaxID=56192 RepID=UPI0005D3CA03 +---IGQYLRDTEQQIQGQIGVAVIDTQNNTQW-NFNGSERFPMMSVFKTLACANVLYDVQ +HKALKLTDKIDVTKAGLINWNPITQNFVGGKMSLQSVCGAAMLMSDNYAANLALEKIGGP +QGLTAFLRTIGDNSTRLDHFEPKLNYVEKGAKNDTTTPIAMMNTVKKLLIGNVLNAENKA +QLQLWMTNNMVSDGLARAVLPQGWKIADRSGGGVNGSRTLTAMVWNKDHQPVFIGIFIAN +SKKTLPELNKVMVAISEKIFHQy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A2U9Q5I5_ACIBA +------------------------------------------------------------ +------------KPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAARI----- +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter xinjiangensis TaxID=762261 RepID=UPI000F7DE00C +-----AELRALEESANGRLGAYILDLADGTAF-GWRADERFTHASSFKMSLAAMMLSKAD +AGQINLDEVLRWTKDDMLFVSPVTQANLNTGLSVRELARATLVTSDNTAANVLLRRFGGP +AELTAFWRSIGDLDSRLDRYEPELNVTPPGTELDTTTPAAMARTTARLVYGDVLTHGSRA +VLKNWMAQVKTGQGRIRSGFPLNWASGDKTGTGVKHVYVDLAYGEPPGRPPVVVTAYFEP +TRPMDPHAVAVLAAVGRIAT--- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dyadobacter bucti TaxID=2572203 RepID=UPI0011096C9C +-qDLKAGITEIVGKANGTIGVGIMHLETRETT-IVNEKHKFPMQSVFKFPLAMAVLDQVD +KGKLSLDQKIHITKKDLLPHSPLRDKYPDGNITLAAILDATVSWSDNNGCDILFRLLGGP +KNVQAYIHNLGVKDIAIVATGEEMSRHWDVQFTNWCEPKAMLQLLNIFQKGKKLSKSSTD +FLRKSMVDSPTGPKRIKGLLPKTAVVAHKTGTSGTAANNDVGIITLPDGKHIALVVYVSN +STLDEKGRDLVIAQIAKAAYDHy +>[subseq from] Beta-lactamase n=3 Tax=Aeromonas TaxID=642 RepID=D5HSX5_9GAMM +---LKEQIETIVTGKKATVGVAVWGPDDLEPL-LVNPFEKFPMQSVFKMHLAMLVLHQVD +QGKLDLNKTVAVNRAAVLQWSPMMKDHQGDEVTVQQLLQYSVSHSDNVACDLLFELVGGP +AALHAYIQSLGIKETEVVANEAQMHADDQVQYKNWTSMKAAAQLLRKFEQKKQLSETSQA +LLWKWMVETTTGPQRLKGLLPAGTVVAHKTGTSGTAATNDIGVIMLPDGRPLLVAVFVKD +SAESARTNEAIIAQVAQAAYQ-- +>[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. WMMB499 TaxID=2650775 RepID=A0A5J6UCE8_9ACTN +--ALRKTLAELENSHDTRIGAVGIDLATGETV-GYRAGERFPFNSMFKVFACSAVLHEAR +TGRGLMDEVIRWTPDDMAANSPETTEYTDTGMTPAQLCRAGITKSDGFAGNMLLKQIGGP +SGLTAFFRSTGDRVSRLDRPEPYLTEWEPGRVRDTTTPAASARTFAELTTGTTLHPRDRA +RLVGWLDASLTGAERIRAGLPDDWTVGDKTGTGGHGSAGDIAIVRPPGSAPLILSVLTNR +KTDDTPNDNEVIARTATALAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044C6625 +------------KKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1H3 TaxID=2080567 RepID=UPI000CE83BF0 +---VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTAAGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIDPGSIDDTTTPAAFTADLVAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR +NDPEADYDDALVARAAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0002B9AB3B +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGXLLTLASRQ +QLIDWME----------------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium iliopiscarium TaxID=56192 RepID=A0A2T3MQE4_9GAMM +---IGQYLRDTEQQIQGQIGVAVIDTQNNTQW-NFNGSERFPMMSVFKTLACANVLYDVQ +HKALKLTDKIDVTKAGLINWNPITQNFVGGKMSLQSVCGAAMLMSDNYAANLALEKIGGP +QGLTAFLRTIGDNSTRLDHFEPKLNYVEKGAKNDTTTPIAMMNTVKKLLIGNVLNAENKA +QLQFWMTNNMVSDGLARAVLPQGWKIADRSGGGVNGSRTLTAMVWNKDHQPVFIGIFIAN +SKKTLPELNKVMVAISEKIFHQy +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. LPMIX5 TaxID=2305887 RepID=A0A399U9M3_9CAUL +------DLSALEARHGGRLGVSVLT--EGKRA-DWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRAIPVTQADMISHAPVTEPAVGRALTIEQLMKGAVEVSDNPAANILIREMGGL +EPLRAFYRGIGDETTRVDRLEPELNRA--DGDKDTIQPAQSARNIERLILSEALDSAFKR +LLLEWMVASPTGQARLKAGVPSGWTVAHKTGTGGDGPVNDIGVLYPTDGAPIAIAVYFHA +TKSTDAQREAVVADATRQALK-- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium jeonii TaxID=266749 RepID=A0A0C1FRY6_9FLAO +-qNLKKEIFDITKNKNATVAVSINSFENQFNL-NINGDKKLPMLSVFKFHIALAVLNKVD +EGKLSLNQNIFIKKSELLEWSPIREKYPEGNMPLSELIKYTVAQSDNNGCDILLRLIGGT +KTVQKFINSKGIKNFQIKANEEEMHQSYKAMYENFTTTNSANDLLKKFYNDKIVSKNSTN +FLMKIMIETTTGTNKIVAQLPKGTQVAHKTGSSGKNAENDIAIITLPNGKHYAISIFVSD +SMESAETNTKMIADISKIVFDYf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WJR8_9BACT +-aELQKQIEQIAAAAKGRVGVRAVTLETGEAV-SLNPQEHYPMQSVYKLPIGMAVLEQVD +AGKIKLEERVRVEKSDYLKHSPIRDNNPDGTLSVRELLRLAVSESDGTASDVLLRLVGGA +EAVTKYLNRLKVTGIIVANSEKEIGQDWETQYRNWASPEGAVTLLRALHERRALSEQSTA +LLLKFMTESPTGPKRLKGLLPQGAVVAHKTGTSGNAATNDIGIMTLPNGRHVAIAVFVSD +SPAGIATSEAVIAKVARAVWDKw +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chitinophaga sp. XJ-2 TaxID=2164099 RepID=UPI000D6A8703 +-----QNIATIATEAGGTVGVAIRNLHTGDTL-TLNDTARLPMQSAYKFPIAMAVLKQVD +EGKLRLDQTIPVTTADLFKYSPLQDSFPKGTQTVADLIRLMVAQSDNIACDVLLKTIGGT +KVANDFIHSLGVQNISIAATEEEMHSGWDVQFTNWCNVSAYTQLLDILQKGTALSKSSND +FLMQTMLGTTTGPKRLPGLLPPGTPVAHKTGTSGYSATNDAGIITLPNGQPLAVVVFVTR +STASEAVREGVIAKIAKAAYDYy +>[subseq from] Beta-lactamase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A2A3ZKX6_9MICO +-qKVSGELESLEEDFKARIGVSAVDTGNGTNF-DYRSDERFGFASTLKVFAVAELLARTT +--SADLDEQVTWTQADVDEWTPLTEKHVDTGLPLRDVAESALRVSDNAAMNIVLDEIGGP +RELDAALEDAGDPTTEVIDEEPELNDVDPDSSDNTTTPKAYTADLQGLLDPDRLPEDDRE +VLLEWMSDNETGDPLIRAGAPKGWTVKDKSGHSD-GIQNDIAVVYPPSEDPIIITVLTQS +EDPDSEDGPALVAAAAEAVFDSf +>[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. WAC 06369 TaxID=2203193 RepID=A0A429G226_9ACTN +-tALDETLAEIEKSRGVRIGAAGIDLATGKTV-GYRAGERFPFNSMFKVFACSAVLHKAR +TDPGLMDKVVRWTPGDMTGNSPETTEYTDTGMTPAQLCRAGITKSDGFAGNKLLDQIGGP +SGLTRFFRTNGDRVSRLDRPEPHLTEWEPGQVRDTTTPAAAARTFTGLTTGNALHPSDRA +RLVGWLKASLTGADRIKAGLPSDWTVGDKTGTGGHGTAGDIALVWSPGTEPMVLAVLTNR +TTDDTPHDDKAIAETATALA--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520JKT8_SPHSX +-------VADYETASGGHVGLYARNLTTGRAI-AWRADERFVMCSTFKASLAACVLNRVD +RGRARLADRIALSPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLQRIGGP +AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMAATIGRMTRGPVLSPSSRA +LLMLWLRQCRTGAARLRAGLPRGWAIGNKTGNNGKDAAGDIGLLWRDPDRP--------- +----------------------- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. TaxID=239 RepID=A0A5N7ZE08_FLASP +-nRLKAQFQEIVKDKKATVGIAVYNFTTGDTL-TFNNNPEYPTLSVYKFHVALAVLHLVD +KGTLKLDQEIFVKKSELLEHSPLRENYPYGNIKLSELLSYMVSLSDNNACDILFRLAGGT +KKVDRYIKNLKIKDTRIAATEEEMHQKWENQYLNTTSPWAAVQLLQKFYQMKILSPTSYD +YLLNVMLSTKTGPDKIKGLLPKDILVAHKTGSSFKAAENDIGIVFLPGGQTYAIAVFVKD +SMEDDTTNNAIIARVSKAVFDHy +>[subseq from] class A beta-lactamase n=1 Tax=Indioceanicola profundi TaxID=2220096 RepID=UPI000E6AD44B +---LEKALSDLATAHPGRVGIGVRDLATGATT-LVGGGRRFPMQSVFKFPIGIAVLDAAD +RGALTLDQTVKLTPADMSVWSPLRDRLAGQPDTVRELLELMVAQSDNTACDVLLGMIGGP +EAVTALLRAKGIDGVRVDRAERELQTAYLDDPRDTSTPEGMLDLLAAFHDGRMLSEAGTA +ELRRIMLSTTTGTKRLKAGVPPGWRVAHKTGSGWTVANNDVGLLIAPNGRTLAIAVFIAG +STAPMEEQEALIAAAARAAT--- +>[subseq from] Beta-lactamase n=1 Tax=Francisella opportunistica TaxID=2016517 RepID=A0A345JRR1_9GAMM +--QVNNDIQNIEKKYGGKIGVYTINRNDGSNF-AVNASFYFPICSTYKFLVVGALLKQSM +TDNKLLNQQVKISKNQIVGYSPITKKHINQTMTVRELCKASMQ-GDNTATNILIEKLGGL +KNLNKFILSLQDHATKIANLEPKVNHVSLTTNENKTTPKVMAKDINKLAFNDLLDKKHRL +MFKKWLIASSTGNNRIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ +SQKNAKPNSKILREVTKILLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=UPI0009C33872 +--TLQEQVKQYEKE-GWKVGLSILS-SDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD +AKKLSLNHSMVVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP +EALTEFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDASKA +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK +ADTSLDERSAVIRTLGSHIFDEy +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium defluvii TaxID=160396 RepID=A0A495SNP3_9FLAO +---LEKRINTILKDKKATVGVSVLGIETGFQY-NKNGEKKLPMQSVFKFHIACAVLDFVD +QGKLSLDQKILLKKSDLLEWSPMRDKYPNGNVTLNEIIDYTVALSDNNGCDILLRLIGGP +KTVQKFMDSKGVTGFQIKFNEEEMHRDWNVQYENYSTTRSIVQVLKKFYDGKLLSKKSTD +YLMKVMLGTKTGANKIVEQLPKTTPVAHKTGASGTGAENDMGIITLPNGKHFAIAVFVSN +STETDAVNCKIVSDVTKVVWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=UPI00114EF3C2 +--TLQDQVKQYEKE-GWKVGLSILS-SDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD +AKKLSLNHSMVVTEKNIVTYSPVAKDYINKPFTLEQACKAANEYSDNTAANFAIFSGGGP +EALTEFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDASKA +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK +ADTSLDERSAVIRTLGSHIFDEy +>[subseq from] class A beta-lactamase n=1 Tax=Serratia TaxID=613 RepID=UPI0007455437 +--TLQDQVKQYEKE-GWKVGLSILS-SDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD +AKKLSLNHSMVVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP +EALTEFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDASKA +QLKEWMVNNKVADNMLRASLPKGWEIADRSGASDYGVRGITSMVWSNNHDPIFISIYVRK +ADTSLDERSAVIRTLGSHIFDEy +>[subseq from] class A beta-lactamase n=1 Tax=Steroidobacter cummioxidans TaxID=1803913 RepID=UPI000E30F3D6 +---LEAEIARLSAPIGGKVGVAAWQLDKGERI-LVNAGERFPMASTFKIAVAGAILANVD +AGKLQLEQLVAVQPTDIVPSDGVASLAIHPGLSVQNLLELMLTLSDNTATDVLTRLAGGP +QAATAWVRKQGIEDQRIDRDTATLLRAFDNDVRDTSTPTAMAQLLTKIFNQQALSVSSTK +VLIDIMQRCRTGTGRLPGRMPAGTVIAHKTGTVG-GTVNDVGVMTLPDGSQIVIAVFIKA +SDQPMEERERVIAEIARSVRDHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Mycobacterium sp. GA-1841 TaxID=1834154 RepID=A0A1R0V2S8_9MYCO +---------------------------------------------TFKAYAVARVLQLVE +RGQLSLDHRVFVDPQAIVPNSPVTETHAGAEMTVAELCQAALQRSDNTAANLLLKAIGGP +AAVTEFARSVGDERTRLDRWEVELNSAEPGDARDTSTPAALAVGYRAILTGDALSPAQRR +QLDDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAYGPGGQRILLVMLTRS +QADDAENQRPVIGELTALV---- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1E6 TaxID=2080554 RepID=UPI000CE87B57 +---VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDSTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVAIGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR +NDPEADYDDALVARAAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Oceanicola sp. HL-35 TaxID=1305735 RepID=UPI0009DCB0CD +-------------------------------------------------------LSRVD +AGKEDLSRVVKYTPDDLVTYSPLTETRVEDGMNVAGLCEATVTLSDNSAGNLLLTTLGGP +EGLNTFLRSIGDETTRLDRWETELNEGALGDPRDTTTPTAMLASLESLLFGEVLSETSRE +QLADWMVADQVADELIRASLPEGWRIGDKTGAGGNGSRSVVAVIWPPEGGPVLAAVYMTD +NTAEFRARNEAVAEIGAIMIE-- +>[subseq from] Beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=A0A1S1IST8_SERMA +--TLQDQVKQYEKE-GWKVGLSILS-SDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD +AKKLSLNHSMVVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP +EALTEFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDASKA +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK +ADTSLDERSAVIRTLGSHIFDEy +>[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas alba TaxID=74314 RepID=UPI001439AA73 +-------LSVLERENGGRLGFVAHDIGSGRRL-AWRGDERFVYCSTFKMYLAAATFLRVQ +AGEERLDRMIPVTAADMVNNAPVTEPAIGGTLSVEALMKGTVEVSDNPAANLLLKALGGL +DVMQAFYRSLGDDSTTANRFEPTMNRL--DGDKDTITPLHSAANLKRLLVDTPLSAGHKA +MLLRWMTDTPTGQARIKAGLPTGWTVAHKTGTGGYGPTNDIGVLYPPTGAPVIVAAYYHA +STEPVARNEAVIAAATRQAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas soli TaxID=266127 RepID=UPI000A052EFA +---AIAELRALEQSANGRLGAYILDTATGLGF-GWRENERFAHASSFKMSLAAMILAGAD +AGTIDPDEVLRWTSKDMLWVSPVTKANLDKGLSIRELAKATLITSDNTAANVLMRRLGGP +EKVTAFWRSIGDNVSRLDRYEPELNETPPGTDLDTTTPAAMAASVARLVHGDALALQSRA +LLRAWMAEVKTGQARIRAGFPAEWHSGDKTGSGIKHVYVDLAFGGPLGRAPLIVTAYFEP +KRPMDPQAEAALAAVGRLAA--- +>[subseq from] Class A beta-lactamase n=2 Tax=Photobacterium TaxID=657 RepID=A0A2T3KNR6_9GAMM +--DLEQYLRHTEQQIQGQIGVAIIDTQQHSQW-NFNGSNHFPMMSAFKTLACANVLYDVQ +QHKLSLTNKIKVTKAGLINWNPITQNFVGGQMSLQSVCGAAMFMSDNYAANLVLEQIGGP +QGLTEFLRTIGDKKTRLDHFEPKLNYVEKGALNDTTTPIAMMNTIKKLLTGNVLDSENKA +QLQLWMTNNMVSDDLARAVLPRGWKIADRSGGGVNGSRTLTAMVWNEHQQPLFIGIFIAN +SKKTLPELNRVVASISAKIFNKy +>[subseq from] Class A beta-lactamase n=1 Tax=Brevibacterium sp. S22 TaxID=2483794 RepID=A0A4Z0JXR3_9MICO +hrQLDTQLTNLEDRYDARIGVSAIDTGTGEAV-DHRGDERFGFASSLKVFAVAELLDRTT +--PKQLKKHVTWSQADVDEWTPVTSKHVDDGLPLAEVAESALRVSDNAAMNIVLDELGGP +DGLDEALHKGGDTTTEVTDEEPELNNVEAGSTDNTTTPAAFTADLHGLLDPQRLSDDDRD +VLLDWMSDNATGDPLIRAGAPDGWTVQDKSGHSD-AIQNDIAVATPPDRDPIVVSVLIET +EDPESADGPAVVAAVAEVVLDEf +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium kishitanii TaxID=318456 RepID=UPI000D16BE8C +--DLEQYLRHTEQQIQGQIGVAIIDTQQHSQW-NFNGSNHFPMMSAFKTLACANVLYDVQ +QHKLSLTNKIKVTKAGLINWNPITQNFVGGQMSLQSVCGAAMFMSDNYAANLVLEQIGGP +QGLTEFLRTIGDKKTRLDHFEPKLNYVEKGALNDTTTPIAMMHTIKKLLTGNVLDSENKA +QLQLWMTNNMVSDDLARAVLPRGWKIADRSGGGVNGSRTLTAMVWNEHQQPLFIGIFIAN +SKKTLPELNRVVASISAKIFNKy +>[subseq from] Beta-lactamase n=1 Tax=Caulobacterales bacterium RIFCSPHIGHO2_01_FULL_70_19 TaxID=1797585 RepID=A0A1F8I429_9PROT +-------LSSLEARNGGRLGFVALDTAGGRSV-GWRAQERFVYCSTFKMYLAAATLERVQ +RGEESLAREVSVVAADMVSHAPVTEPAIGSTLSIEALCKAVVEVSDNPAANILIREYGGL +AAWRDWYRSIGDESTTVDRLEPEMNRE--DGDKDTILPAQSVANMQRLFVNDPLADDSRD +RLLRWMIDSPTGAGRIKAGVPAGWTVAHKTGTGGYGPTNDIGLAVPPSGDPVVIAAYYHA +TPSSASANDAVIAEAVRLAL--- +>[subseq from] Beta-lactamase n=1 Tax=Pedobacter sp. BAL39 TaxID=391596 RepID=A6EA88_9SPHI +---LKQKIKQQLSGKKATVGISIQHLETGQTL-TINNDKHYPMQSVYKFHIAMAVLNQVD +KGKLQLQQNIYIKKSDLLPWSPIREKYPEGELPLSDLIRYTVAQSDNNGCDILLRLLGGP +KLVNNYIHKLGIEDVSIQATEEQMHQSYPVQFSNWSTPKAATDLLLLFYQQNTLSKQSFN +FLWETMLSTTTGKKQLRGQLPLNTPVAHKTGNSGTAALNDIGIITLPDGTHILISVFVSN +SKENSETNESIISDIAKTAWDYf +>[subseq from] Beta-lactamase n=1 Tax=Deminuibacter soli TaxID=2291815 RepID=A0A3E1NF23_9BACT +---LNHTIAQFAQRSQGKTGVFAQVLETGDTA-GFYATDRFPMQSVYKVPIAMAILAQVD +KGKWQLSDSILVLPSDLLKHSPITDEHPQGNITLADLLQLAVGESDGTASDVLLRILGGP +QKVKKYLHHIGVKHVAVANTEKEIQGEWEVQYSNHATPEAIGKLLRTLYTKDALSLPSRD +ILLKWMTESTPGAARIKGLLPPGTPVAHKTGTSATAATNDAGIITMPNGHHLVVVVLVSN +SPADTPTRENVIASITKTLWDTw +>[subseq from] Beta-lactamase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8LSP8_9BACT +-kKLRNEIEQITLAAKGRVGVAAVVLETGETV-SLSPHDHFPMQSVYKLPISMAVLKQVE +AGKIKLDQKVSVTKKDFVRNSPIRDKYPNGTITVNELLRYAISESDGTASDVLIKLAGGP +GAIQTYLSELKITDLTVLNTEKEIGQDWETQYRNWSSPEAAVALLRALHERRGLSGSSQT +LLLKFMIESTPGPKRLKGLLPTGTIIAHKTGTSGTAATNDIGIITLPNGKHLAIAVFVAD +SAADEASREGVIAKIARAVWDTw +>[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis terrae TaxID=33052 RepID=UPI000787EF97 +--SVANRIDALEKKSGGRLGVAVTDQFGKLIV-GHRADERFAMCSTFKLLLAAQTLTAAK +-NGVSLRTPLAFTRADLLPHSPGAERLLDAEYRIGFAAEDAVVLSDNLAANLLLDHFGGP +TAFTDHVQATGDLVTRLDRVEPDLNANIPGDPRDTTSPAAMAKSAAAYIFGDKLDPAYRT +MLRDWLVKSETGLARIRAGLPRTWHVGDKTGTCGT-AYNDVAFVEEPGGDKYMIAVYLDR +PALKGDAANAIIADVARAVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3A6RJC2_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDW------------------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=UPI001021B0D8 +--TLQDQVKQYEKE-GWKVGLSILS-SDDKTI-SINGSQRFPLDSTVKSIACANVLAKVD +AKKLSLNHSMVVTEKNLVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP +EALTAFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDSSKA +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK +ADTSLDERSAVIRTLGSHIFDEy +>[subseq from] class A beta-lactamase n=1 Tax=Shewanella aestuarii TaxID=1028752 RepID=UPI001425E060 +---IAQKLEALSKGLVGSIGIAAQEMSTGECI-TVNGDESFVMASTYKVAIAVTVLRQVD +EGKLKLTDLVDCPAEKMVAPNPLATYHPGVKLSVANLIEPMITDSDNSATDFLLELVGGP +EVVTQMLRSLGITDFRVDRYVSEILRDYEKDPRDQTTPNAMLQLLLAIDNGTALSEESRE +FLLGVMSRTTTGKARLQGLLPKGTPVADKTGTIG-GVANDVGYVTLPDGRRFAIAVFTKS +SATSEAQRECAIAEVTRSLYDFy +>[subseq from] Beta-lactamase n=1 Tax=Dyadobacter sediminis TaxID=1493691 RepID=A0A5R9KEK7_9BACT +-dELHASIDSISKRVQGTVGVGIMELKSGETF-FLNKAHKFPMQSVFKFPLGMAVLHQVD +KGKLSLDQKIHVTKDDLNPWSPLQKKFPEGNISLRDLLIYTVSLSDNNTCDILFKLVGGP +RNVNKYIHNLGVKDINIVATEAEMAKSWDVQFTNWCQPPAMIQLLHILHQGKNLSESSTE +FLLKIMTETPTGLNRIKGLLPENTKVAHKTGSSGTNAFNDAGIVTMPNGKYIAIVAFVSN +TAADEKTRDLVIAQISRAAWDYy +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A3D3MJU5_9FLAO +-kALDNKINAVIKDKKATVGVSVLGFENNFTY-DKNGDKKLPMLSVFKFHLACTVLNLAD +KGKLSTDQKILIKKEDLLEWSPLREKYPNGNLSLGEIIDYTVSKSDNNTCDLLLRLIGGP +QAVQHFMNSKGVKNLQIKYNENDMHKDWKTQYGNYSTTHSAVDLLKKFYDGKIISKKSTD +FLMQIMLGTTTGTNKIVAQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVNN +STESDEVNTKMVADISKIVWDNf +>[subseq from] Beta-lactamase n=1 Tax=Tanticharoenia sakaeratensis NBRC 103193 TaxID=1231623 RepID=A0A0D6MMF7_9PROT +-----ASLAALERRIGGRVGVCALDTGTGARI-VYRETERFVMCSTFKWLLAAAVLQRAA +SGGPGLDSSVPIRADAIVSHSDATKPFVGRSMTLRLLCAAMMATSDNGAANTLMRAIGGP +AALTRAVRTWGDPLTRQDTYELGPD-ARPGDLRNTTTPAQMLADMQHVWLGDALDPASRA +QLIAWLRSCVVGQHRLRTGVPGQWVEGDRTGTGDPGSINDLAIFWPSKRAPVLVASFLSG +SQHSAVQLETAQGEIGRIVADTf +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00069EA316 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKKQEPIILVIFTNK +DNKSDKPNDKLI----------- +>[subseq from] class A beta-lactamase n=1 Tax=Listeria thailandensis TaxID=2268407 RepID=UPI000F091C5C +--SVNERLEVLENKYHAKLGVYAAN--GNEKV-KYNAQERFAYTSTYKAIISGLLLKNRT +--EEELQKKIFFSKEDLVDYSPITEKFVDKGMTLKAIIHAAVAYSDNTAGNLLFDEIGGT +KKFQEELRLIGDHTTISSRYETDLNSAVPGDLRDTTTPEAFGTDLQRLTSPKCLDPQALS +YFKQTLVDNTTGDKLIRAGVPEGYIVGDKTGAGSYGTRNDIAIIFKENSLPLVWAVFSKM +DREDAQYNDQLIADVAKVLS--- +>[subseq from] Class A beta-lactamase n=1 Tax=Francisella halioticida TaxID=549298 RepID=A0A2Z2LDL7_9GAMM +---ISNNIHKIESHYGGKVGVYTINRNNGQNF-SHNETFYFPICSIYKFLVVGAILKESM +ADSNLLDEKIRISGNQIVGYSPITKKHIGKEITVRQLCKASI-LSDNTATNLLIDKLGGL +KKLSTFILSLKDHATKITALEPKINDISLNNNLNKTTPKIIVRDLNKIAFKNILDKKHRT +LFKKWLEENNTGSNRIAAELPKDWKIGDKTGTCDYGSTNDVAIIWPNNDKAIIMAIFYTQ +PNKNAKPNNKVIREVAKILFDNf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. SNU WT5 TaxID=2594269 RepID=A0A516NZ93_9FLAO +--TLKKEIKQIIKGKNATVAVSVLDFENNKSI-DINGNKKLPMLSVFKFHIALAVLNQVD +EGKLSLDQNIFIKKSELLLWSPIREKYPEGNMPLNELIKYTVAQSDNNGCDILLKLIGGT +GTVQSFINSNGIKDFQIKADEEKMHQGYEFMYWNWTTTNASNTLLKKLFDGKVVSKKSTD +FLMKTLIETTTGVTKIVAQLPKGTPVAHKTGSSGKDAENDIGIITLPNGKHYAISVLVSD +SMESEETNTKTIADISKIVFDYf +>[subseq from] Class A beta-lactamase n=4 Tax=Hyphomonadaceae TaxID=69657 RepID=A0A354C945_9RHOB +----HTAIAYMESQNGGRFGVSAVNLATGQTI-THRGDERFAMCSSFKWLLAALVLQRVQ +AGEEDLSRMIEFTEADMVMHAPITEPALGEGLSVEALCRGTVQTSDNPAANLLLRTLGGP +EGFTQILRDNGEMTTRLDRWEPMLNENAPGDPQDTSTPNAMVSLMGYYLFGGGLNAEYQT +LLKDWMIGATTGLARLRDGMDAPWIGGDKTGTSSNNQSNDVAFAYRPDADPILITSYLNV +ENPVGAETDELHATIGRQIM--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseoflavus Tu4000 TaxID=467200 RepID=D9XL75_9ACTN +------------------------------------------------------------ +----RLDRRVTYTRADLVPHSPVAEKHLATGMTVRQLCDAAIRFSDNAAANLLLRDLGGP +RAVTAHLRRLGDRVSRLDQSEPELNGNPPGDPRDTTTPRAVAADYRALVLGDALPGAKRD +LLADWLVRNTTGGRRIRAGVPRDWRVGDKTGTGEWGRVNDVAVLWPPSGAPLVMAVLTDR +PGRADTTDEALVAEAARRVL--- +>[subseq from] Class A beta-lactamase TEM family n=1 Tax=Citrobacter braakii TaxID=57706 RepID=A0A3S8XA06_CITBR +------------------------------------------------------------ +-------NASIILKNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium kishitanii TaxID=318456 RepID=UPI000D15D39D +--DLEQYLRHTEQQIQGQIGVAIIDTQQHSQW-NFNGSNHFPMMSAFKTLACANVLYDVQ +QHKLSLTNKIKVTKAGLINWNPITQNFVGGQMSLQSVCGAAMFMSDNYAANLVLEQIGGP +QGLTEFLRTIGDKKTRLDHFEPKLNYVEKGALNDTTTPIAMMNTIKKLLTGNVLDSENKA +QLQLWMTNNMVSDDLARAVLPRGWKIADRSGGGVNGSRTLTAMVWNEHQQPLFIGIFIAN +SKKTLPELNRVVASISAKIFNKy +>[subseq from] class A beta-lactamase n=1 Tax=Microvirga flocculans TaxID=217168 RepID=UPI00047FA4C3 +-dALRAKIEALDKKSSGRLGVGLVDLTDGDSW-SWRGDESFPMQSVYKLPIALAALKAVD +EGRRNLDERISLGREDLSIWSPIAREFKGEPYTVRQLLEHALQQSDNTASDVLLRLVGGP +GSVTALLRRHGIDGMRVDRPEREMQPAYLADGRDTATPKAAAHLLAKLARGELLSKPTTR +IFLDILAGTRTGGSRIKAGVPEGSTVAHKTGTAMDVAVNDAGLVTLPERRQLVVAVFVAG +SDSSPAERERLIADVTRAAIE-- +>[subseq from] Uncharacterized protein n=1 Tax=Williamsia sp. Leaf354 TaxID=1736349 RepID=A0A0Q5QA65_9NOCA +---IDAQIVASAKRAETTIGVWARDLRTGRVIaAVNAGERFPVLSMSKVYLAAAVLDAAR +HGRLLLTRPVPVRASDIVANSPETGKHVGGTMTYPEIAVAALQLSDNTAANLMFAAIGGP +RALTAFARSTGDPATLMVRQETALNTAFPGDVRDTTVPQAWAAGLRAVMVGTRLDPRDRT +TLVGWMRGTRTSDKRFRADLPAGWTTADKTGTGDYGSADDAGLLIGPGGRRILLVVQTRN +ARPDATAADTVIARVASLVAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Eudoraea adriatica TaxID=446681 RepID=UPI00036495FD +-kEVSQKIEKLTEGLVGRIGVAAQEIGGDEVI-AVNGDETFAMASTYKVAIATTVLDRVD +KGELSLDQMVDVPQDMYVATVAIAERFPYSGFSLANLIYAMITESDNTATDVCLRLAGGP +AAVTENLRRLGIKDFRVDRSVREILMDFEADPRDHTTPNAYLKLLLAIEGGKAMSPKSRE +FLLGVMSRTRTGAGRLRGMLPKGTPVAHKTGTLG-GVANDVGYITLPDGRRFAIAVFTNS +SKTPDSDRERAIAEVARALYDFy +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI00065C1A99 +--ATTQDLKKVEDKYDANIGVYALNTATDKEI-TFNEDKRFAYASTFKAISSAMLLEKTP +--HDELNKKVYVSKEDIVPYSPVLEKFINKDISIKKLIEATMLYSDNTANNMIIEELDGY +KEVNKRLKSLDDKTTKPSRMEPELNNYNPKSNRDTSTPQAFGKTLNKLIKDGRLSKENKT +FLIDLMVHNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK +EGKTDKPNDKVVSETAKVVLEKf +>[subseq from] Beta-lactamase (Fragment) n=6 Tax=Escherichia TaxID=561 RepID=A0A345N8A2_ECOLX +---------------------------------------------------VAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLILV----- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Pedobacter nutrimenti TaxID=1241337 RepID=A0A318U9U3_9SPHI +---LHKKLNAIAAAHQAHIGFSLLDLQSGDTV-SLNGQKHFPMQSVYKFHLALAVLNKVD +QGKLKLEQKIHLRKQDLLPWSPLRDKYPSGEIPLSELLSFTVSQSDNNGCDILFRLIGGP +IAVQRYIHGLGIKDVAIVATEEQMHQNDQVQFRNWSTPVSAARLLKLFYSKNILSASSKD +FLWKIMTETTTGPNKIKGMLPKGTPVAHKTGSSGTAATNDIGIVTLPNGGRFALVVFVSM +TKENEQGSDKIIAELSKAGWDY- +>[subseq from] Beta-lactamase n=1 Tax=Zymomonas mobilis TaxID=542 RepID=A0A542VZ02_ZYMMB +----EEIAREYERATGGHAGIYAQNIATGQSI-AWRANERFLMCSTFKASLVAFTLLRCD +QRQESLNHSVDYKAADIGDYAPFAKSNLGRGMSVAELCQGAIEQSDNFCANKLLACSGGA +LALTEFWRQIGDYESRLDAIEPFLNETRYGGIENTTTPASMARNLQKVVLGGVLSETSKQ +QLATWLKGCRTGQNRIRAGLPENWVIGDKTGTNGANAAGDIAVIWPRPDKAITLSIYVWG +GSPTADQMTALFSKAARLVAK-- +>[subseq from] Uncharacterized protein n=1 Tax=Flavobacterium sp. 40-81 TaxID=1896169 RepID=A0A1Q3S2N9_9FLAO +--NLRAQINEIIKDKKATVGVGIYNLTNNDTL-TINNTHHFPTMSVYKFHLALAILHQVD +KGKLRLDQEIFVKKSDLLEHSPLRENYPYGNIKLSELISYTVSLSDNNACDILFRLAGGT +KKVDRYIKSLKIPNTSIQATEAEMHEKWENQYLNTTTPFAAVLLLKKFYQLQVLSPTSYD +YLLNVLQGTKTGPDKIKGLLPQNVVVAHKTGSSFKAAENDIGIVYLPGGQAFAIAVFVSD +SMESDTTNNKIIAAISKAAFDYf +>[subseq from] class A beta-lactamase n=1 Tax=Agromyces sp. H66 TaxID=2529859 RepID=UPI0010A9B0B7 +--RMTAALAELEREASVTIGVVAVAHGSTNPF-RYRAADRFPMCSLFKPLAAAALVQARG +YDEVYWNTPIPYTNADVVVDSLVLESKRPQRATPEELADAALRWSDNTAGNLLLRELGGP +AAITAFAASLGATDTRLDRWEPELNEAVPGDLRDTTTPDDIALLYSALLLDDAAGMLTSA +RLREWMLRNQTSNARMRAGLEPPYELADKTGGGAYGVVNDAGVLWRPGETPLTLVIMTRT +DRADAVRNNAVVAEATRIVV--- +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium sp. SKA34 TaxID=121723 RepID=Q2BZ61_9GAMM +--ELNITLRQMEKQIDGNIGVAVFDSQTNTSW-NFNGNKRFPMMSAFKTLACANVLYDVQ +QHKLSLTNKIKVTKAGLINWNPVTQNFVGGQMSLNSVCGAAMLMSDNYAANLALGQVGGP +HGVTKFLRMIGDKTTRLDHFEPKLNYVEKGAENDTTTPIAMMNTIKKLLTGKVLDSESKV +QLKFWMTNNMVSDGLARAVLPTGWKIADRSGGGVNGSRTLTAMVWNKHHQPLFIGIFISN +SKETLPELNQVVASISAKIFNKy +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter oceanensis TaxID=1463597 RepID=UPI00136F9993 +-qDLASRMAEIEAASGGRLGVALHSPDAGTVF-LHRGDERFAMCSSFKLALAAMALERPG +----LRDARLGFGPDEVLGYAPYAKQRAALGMSGLEAARHSVTISDNTAANLLLAELGGP +DGFTAWLRGFGDDKTRLDRNEPALNENAPGDPRDTTTPQAHAKLVADLLWGDRLAAADRS +LLREWLVETSTGMNRLRAGIPDGWQAGDKTGTCGNGQVNDIAVFETPDGARYVLAVYLDR +PSGTTAEAEAAIAQAARAIVA-- +>[subseq from] class A beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=UPI0013A59627 +-----------------------------------------PMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANFLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGTG--------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=E4WMC5_9BACT +-rELQKQIEQIASAARGRVGVHAVVLETGESV-SLDEQGRFPMQSVYKFPIGMAVLAQVD +AGKLKLDERVRVEKSEYVRHSPLRDKNPNEAVSVRELLRLAVSESDGTASDVLFRLAGGS +EAITRYLSDLKVTEIIVADTEKEIGQDWDTQYRNWASPKGAVMLLRAFHEGRGLSAESRA +LLLKLMTDTPTGPKRLKGLLPKGTVVAHKTGTSGSAATNDIGIVTLPNGRHLAIAVFVSD +SPADLTTREGVIAKVAKAAWDQw +>[subseq from] VEB-PER_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X339_9BACT +-aKLKSEIETISKQAKGIVGVGIMDLKTQETL-LINQDHKFPMQSTFKFPLAIAVLDLVD +KGKYKLDQTIHVTKAQIDTHSPMRDKRPNQDITLAELLSYSVSESDNNACDILFELAGGT +KKVNDYIHSLGVKDIAIVATEREMKAGWDVQYTNYSRPSAYLQLLQIAYERKKLSKASHD +FLWKTLVEGPTGLKRIKGQLPKGTEVAHKTGTSGTSATNDVGIVKLPNGKDIAVVVFVSD +AAADIDTRELVIARIAKAVWDYy +>[subseq from] TEM-1 beta lactamase n=5 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A3G1IEN2_KLEPN +------------------------------------------------------------ +-------NASIILKNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVTGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacterium sp. 1.3611 TaxID=2559600 RepID=UPI00112E5B9D +-qDLKKTIETIVGKHTAKIGFSVIDLQNGDTI-GFNGNVRYPMQSVYKFHLALAVLKQVD +EGKLKLDQQIFVTTKDLLPWSPLRDKYPQGNIPLAEILSYTVSQSDNNGCDILFRLVGGP +SEVKRFIHGLGIKDVNILATEEEMHLDEMVQFKNWSTPCAVVQLLKLFYDSKILSTSSND +FLRDIMEKTVSGPNKIKGLLPKGTTVAHKTGSSGTTASNDIGIVTLPNGKHFAIAVFVSM +TNEEEKETDQIIAECSKAAWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Pseudarthrobacter chlorophenolicus TaxID=85085 RepID=UPI0005F281B7 +--RLDTAISGLESAHGLTIGVAAGRLGQRPAY-AYRGGDIFPMCSLFKTLAVARLLRDHA +YDDGFWQHRISFRKNQIVRDSVICAADKDRNMSVEELADAALRFSDNTAGNLLLELIGGP +PEIGTYARSLGALSTRLDRWEPELNEALPGDVRDTSTPSDIHTLYEALLLGDALGTLGQA +RLRGWMLRNATSGERLRAAVPPGAELADKTGAGSYGVVNDAGVVWPEDGPPLTLAVMTRT +SRPDAVNNNAVVARVGQLVF--- +>[subseq from] Class A beta-lactamase n=1 Tax=Photobacterium kishitanii TaxID=318456 RepID=A0A2T3R2T3_9GAMM +--DLEQYLRHTEQQIQGQIGVAIIDTQQHSQW-NFNGSSHFPMMSAFKTLACANVLYDVQ +QHKLSLTNKIKVTKAGLINWNPITQNFVGGQMSLQSVCGAAMFMSDNYAANLVLEQIGGP +QGLTEFLRTIGDKKTRLDHFEPKLNYVEKGALNDTTTPIAMMDTIKKLLTGNVLDSENKA +QLQLWMTNNMVSDGLARAVLPAGWKIADRSGGGVNGSRTLTAMVWNEHQQPLFIGIFIAN +SKKTLPELNRVVASISAKIFNKy +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium phocaeense TaxID=1816690 RepID=UPI0009BB558C +-sSLEQKISSITSGKKATVGVSVLGFENNFKY-SKNGDKELPMLSVFKFHIACAVLDLVD +KGKLSLDQKLFFKKEDMLEWSPIRDKYPDANLSLGEVLDYTVALSDNNGCDLLLKLIGGT +QTVQKFMDSKGVKGFQIKRNEDDMHKNWKTQYDNVSTPNSAVLVLKKFYDGKLLSKKSTD +YLMQMMLGTKTGTNKIVEQLPKGTPTAHKTGASGKGAENDIGIITLPNGKHYAIAVFVNN +STESDAVNCRMVSDISKAVWDDf +>[subseq from] class A beta-lactamase n=1 Tax=Steroidobacter agariperforans TaxID=268404 RepID=UPI00101C7C58 +---LEAEIARVSAPIGGKVGVAAWQLDKGGRV-MVNANERFPMASTFKIAVAGAILANVD +AGKLKLDQLVAVQPNDIVPSDGIASLAIHPGLSVHNLLELMLTLSDNTATDVLTRLAGGP +QAVTAWVRRQGVEEQRIDRDTAGLLRAFDKDVRDTSTPAAMGQLLTRIFNQQALSVSSTK +VLIDIMQRCHTGAGRLPGRMPAGTVIAHKTGTIG-GTVNDVGVMTLPDGGQVVIAVFIKE +SDKPMEARERVIAEIARSVRDYf +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1E3 TaxID=2080551 RepID=UPI000CE768A8 +---VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDSTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLVAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR +NDPEADYDDALVARAAAVVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Williamsia herbipolensis TaxID=1603258 RepID=UPI0005F818B2 +---IDAQIVASAKQAETTIGVWARDLRTGRVIaAVNAGERFPVLSMSKVYLAAAVLDAAR +HGRLSLTRPVPVRASDIVANSPETGKHVGGTMTYPEIAVAALQLSDNTAANLMFAAIGGP +RALTAFARSTGEPATLMVRQETALNTAFPGDVRDTTVPQAWAAGLRAIMVGTRLDPRDRT +TLVGWMRGTRTSDKRFRADLPAGWTTADKTGTGDYGSADDAGLLIGPGGRRILLVVQTRN +ARPDATAADAVIARVASLVAR-- +>[subseq from] class A beta-lactamase n=1 Tax=Streptomyces glaucescens TaxID=1907 RepID=UPI000A35F787 +---LTKKLQALERSYEGRIGAVGIDLETSRTV-GYRADERFPFNSSFKVFACAAVLVKAR +TDPGLMDQVVRWTPADMGGNSPESTEYTDTGMTPAQLCRAGITKSDGFAGNMLLEQIGGP +RGLTAFFRAIGDRTSRLDRPEPLLTEWEPGEVRDTTTPAAAARTFTELTTGSTLRAGDRA +RLVGWLKASLTGANRIRAGLPKDWTAGDKTGTGGHGTANDLAIVWSPGSAPLILSVFTNR +THDNTAHDDKVISSTATALA--- +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium sp. (strain NBRC 103272 / SYK-6) TaxID=627192 RepID=G2IJJ9_SPHSK +-eAARQALAALETRSGGRLGVAMLDSRDLALV-GHRQDERFTMCSTFKLSLAAAMLVRMD +AGAFGEQERLLITRDDAVGHAPAVRAALEDGMTVLDLCAAAQIESDNGAANILLRKLGGP +EALTRFWRALGDDVSRLDRYEPALNTSHGEDIRDTTSPAAMAGALRAIVAGEVLKPASRE +RLTGWTIETRTGLRRLRAGLPADWRAGDKTGSFWGDKLNDIAIVWRPDRSPFFVTAYFES +PIALRPQDEAVLAQVGAIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio TaxID=662 RepID=UPI00046EFE68 +-kDVSQKLETVSQRLVGRIGIAAQEIGSGERV-TVNGDETFVMASTYKVAIAVALLDRVD +KGELKLSDLIDISQDMMVADNAIAQNFVHPGLSVANLIEPMITESDNTATDICLKLAGGP +EAVTKKLRSIGITDQRVDRYVTEILRFEQEDLRDQSSPNAMLELLLAIDSGKALSETSSE +FLLNVMSRTRTGSGRLKGLLPKGTPVAHKTGTIG-GVANDVGFVTLPDGRRFAIAVYTKS +STTSDADRDRAIAEVSRTLYDFy +>[subseq from] class A beta-lactamase n=1 Tax=Yonghaparkia sp. Soil809 TaxID=1736417 RepID=UPI00138F8ACD +---VAAELAALETEYGATIGVLARDTSSGASI-AFGQDRRFGFASTMKAPLAGIFLDRVE +--GAARDEVVRWSAAQVEEYAPVTAERIAEGLTLAELAEAAVRQSDNLAFNLVLERLGGP +AALDAALAELGDETTEVVTLEPELNTIEPGSTDDTTTASALAGTIETLLLGPTLDVDDRA +LLLDWMSGNATGDTLIRAGAPEGWVVADKSGGAG-AIRNDVALVTRPEGAPIVIAVLTQR +DDPEADRDDSLVARAAEIALDAf +>[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas naejangsanensis TaxID=588932 RepID=UPI0004035731 +------DLSALEARHGGRLGVSVLT--EGKRA-DWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRAIPVTQADMISHAPVTEPAVGSTLTIEQLMKGAVEVSDNPAANILIREMGGL +EPLRAFYRGIGDETTRVDRLEPELNRA--DGDKDTIQPAQSARNIERLILSEPLESAFKR +LLLEWMVASPTGQARLKAGVPSGWTVAHKTGTGGDGPVNDIGVLYPTDGEPIAIAVYFHA +TKSTDAQREAVVADATRQALK-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinomadura rifamycini TaxID=31962 RepID=UPI00047C969E +-tALDETLAEIEKSRGVRIGAAGIDLATGKAV-GYRAGERFPFNSMFKVFACSAVLHKAR +TDPGLMDKVVRWTPGDMTGNSPETTEYTDTGMTPAQLCRAGITKSDGFAGNKLLDQIGGP +SGLTRFFRTNGDRVSRLDRPEPHLTEWEPGQVRDTTTPAAAARTFTGLTTGNALHPSDRA +RLVGWLKASLTGADRIKAGLPSDWTVGDKTGTGGHGTAGDIALVWSPGTEPMVLAVLTNR +TTDDTPHDDKAIAETATALA--- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas subvibrioides (strain ATCC 15264 / DSM 4735 / LMG 14903 / NBRC 16000 / CB 81) TaxID=633149 RepID=D9QMV9_BRESC +-------LSALEADNGGRIGFVAHDLGSGRRL-TARGDERFVYCSTFKMYLSAATLMRVQ +AGQERLDRAVPVTRADMVSHAPVTEPAIGSSLSVERLMQAVVEVSDNPGANLLLKALGGL +EAMRAFYRGIGDDSTTVDRFEPEMNRL--DGIKDTMTPARSVANLHRLFVDPTLSADSKT +MLLGWMFTSPTGTDRLKAGVPADWRVAHKTGTGGYGPTNDIGILYPPSGEPVIVAAYYHA +TRTSDSQNAAVIAQATRMAL--- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A3B8UMN7_9CAUL +------DMSALEARHGGRLGVSVLT--EGKRA-DWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRAIPVTRADMISHAPTTDPAVGSTLTIEQLMKGAVEVSDNPAANILIREMGGL +EPLRAFYRGIGDETTRVDRLEPELNRA--DGDKDTITPNQSVRNIERLILSEALDSAFKR +LLLEWMVASPTGQARLKAGVPSGWTVAHKTGTGGDGPVNDIGVLYPTDGQPIAIAVYFHA +TKSTDAQREAVVADATRQALK-- +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. MYSH2 TaxID=2303333 RepID=A0A372NYL1_9SPHI +-tTLREQITELSKDAKGKVGVAMLDLKTGDTL-TINGKRPLVMQSTFKFPIAVAVLHKAD +KGLLKLDDKLHITKKDLPEYSPLRDKHPDGNITIRELLDYMLIWSDNDACDILLNRVCSK +AEVEKYMHQLGGLSFRIRATEDEMKHNWKAQFTDVCTLWDMANLLKTVRHGSALSAKNTD +YILTTMAKTEVGKKRIKGLLPEGTVVIHRTGTSATDATNDAGIINMPGGRQVILVVFVTD +SKADDDTREAVIARIAKAVYD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY2B7 TaxID=2080571 RepID=UPI000CE7D440 +---VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDSTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPDSTEDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTSPGRDAVVLSILSAR +NDPEAEYDDALVARAAAVVL--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. MC1 TaxID=1174684 RepID=N9USN6_9SPHN +--SAANRIAALEKISGGRLGVAVTDQFGKLIV-GHRADERFAMCSTFKLLLAAQTLTAAK +-NGVSLRTPLPFTRADLLPYSPGAERLLDAEYRIGFAAEDAVVLSDNLAANLLLDHFGGP +TAFTDHVQATGDLVTRLDRVEPDLNANIPGDPRDTTSPAAMAKSAAAYIFGDKLDPAYRT +MLRDWLVKSETGLARIRAGLPRTWHVGDKTGTCGT-AYNDVAFVEEPGGDKYMIAVYLDR +PALKGDAANAIIADVARAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Steroidobacter sp. YU21-B TaxID=2695855 RepID=UPI0013225F6A +---LEAEIARLTAPIGGKVGVAAWQLDKGERI-MVNAGERFPMASTFKIAVAGAILASVD +AGRLQLDQLVAVQPNDIVPSDGIASLAIHPGLSVHNLLELMLTLSDNTATDVLTRLAGGP +QAVTGWVRKQGVEEQRIDRDTAGILRAFDKDVRDTSTPAAMGQLLTKIFNQQALSVSSTK +VLIDIMQRCHTGAGRLPGRMPAGTVIAHKTGTIG-GTVNDVGVMTLPDGSQIVIAVFIKE +SDKPMEQRERVIAEIARSVRDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Pedobacter cryoconitis TaxID=188932 RepID=A0A327T396_9SPHI +-nDLRKKLQAIVSSHAATIGFSLTDLQNGDTI-TVNGTKHLPMQSVYKFHLALAVLNQVD +QGKLKLDQKILVKKSDLLPWSPLREKYPNGEIPLSEILSYTVSQSDNNGCDILFRLMGGP +AKVNRYIHSLGIKQVAIVATEEQMHKDENVQFTNWTTPVAATELLKLFYSRKVLSKTSHD +FLWKVMTETVTGANKIKGLLPAGTLVAHKTGSSGTTGTNDIGIVTLPNGKHFAVAVFVSM +TKEDEKTNDLIIAELTKVSWDY- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacterium sp. S22 TaxID=2483794 RepID=A0A4Z0JWV4_9MICO +-qEITADLKTLEQDFGARIGVSAVDTGDGSTI-DYRADERFGFASTLKVFAVAELLARTA +--DEELDERVTWTQADVDAWTPVTEKHVDTGLPLADVAESAVRVSDNAAMNIVLNEIGGP +QGLDEALEDAGDPTTEVIDGEPDLNDIEAGSSDNTTTPAAYTSDFQGLLDPDRLADGDRQ +VLLEWMSDNETGDFLIRAGAPEGWTVKDKSGRSD-AIQNDIAVVYPPDEDPIVITVFTES +DDSDSEEGPALIEAAAETVLGAf +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia paucivorans TaxID=114259 RepID=UPI0002D8EFA9 +--ELDLALTELEDLYGVRLGVHAFAPRRELTY-TRRADERFALCATFMVYAVAALLRREQ +QGRLSLDDKARVEPDQVVENSPVTAPVQGRTMTLGELCAAALVHNDNTAANLLLGRLGGP +RAITEFARTLGDNATVLNRWAPDLNTVARGDPRDTTTPTGLATGYRELLFGSALAPARQR +VLTEWMAANVTSGERIRKGLPDGWTSADKTGAGGYGTVNDAGVVRAPNDDRLLLVLFSDS +TTSDAPNNDVPIAEATAAVVT-- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A3D5MH45_9CAUL +------DMSALEARHGGRLGVSVLT--EGKRA-DWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRAIPVTQADMISHAPTTAPAVGSTLTIEQLMKGAVEVSDNPAANILIREMGGL +EPLRAFYRGIGDETTRVDRLEPELNRA--DGDKDTITPNQSVRNIERLILSEALDSAFKR +LLLEWMVASPTGQARLKAGVPSGWTVAHKTGTGGDGPVNDIGVLYPTDGQPIAIAVYFHA +TKSTDAQREAVVADATRQALK-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Adhaeribacter aquaticus TaxID=299567 RepID=UPI0003FC79A0 +--ALKRNIEDLIASKDATVGVAIYGLESKDAI-YINNNKHFPLQSVFKFHIALAVLSEVD +RGRLTLNQKIRIKKSDLLPWSPIREKYPQGNLPLTEVLKYTVAESDNNGCDILLRLIGGT +QFVNNYLHKLGIKEVSIQANEAEMHQAWDVQFQNWTTPKSTVDLLKLFQERKILSAKSYD +FLWQTMAETVSGKNRIKGQLPAGTVVAHKTGTSGTAAINDIGLVTLPNGTHFAISVLVSN +SKESTETNEKIIADITKLSWNYf +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1A7 TaxID=2080524 RepID=UPI000CE90DA3 +---VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDSTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLVAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Uncharacterized protein n=2 Tax=Pelomonas sp. Root1444 TaxID=1736464 RepID=A0A0Q7SM59_9BURK +------GFAALERRVGGRLGFFALDTGSGRTL-AHRADERFATASTFKILLAARVAHGVD +TGRWRWDDEVPLQASDRVAHAPAFDRLLPRGATLAELVQGIVVESDNPCANLLLRRCDAP +AGLTAWLREQGDTVTRLDRWELALNENAPGDPRDTSTPRAFATTLQHLLLGRGLKRASQA +RLWADMQASRTGLERLRAGVPADWRVLDKTGTGNRGAVNDVALVFPPHGAPWVVAAFQSG +SGAPTDDLSAVHADVMRRLVQTw +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. YR515 TaxID=1855316 RepID=A0A1I2IXD9_9MICO +--AVARTLADLEREYDATVGVVATDTTTGETV-AYNGDRRFGYASTLKAFAAAQFLRAVH +--GADRDERVRWSAADATAHSPVTSEHVADGLTIAQLAEAAVRQSDNLALNLVVDRIGGP +AGLDRALAELGDRTTEVVHDEPALNTIEPGSTEDTTTPAAFAAALATVLDGQTLGRSDTA +LLEHWMSGNATGDTLVRAGAPDGWTVVDKSGGAG-GIRNDVARVTRPDGGPIVIAVLTTR +NAPDTAYDDALVARSAAAALDAf +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A3B9EDF2_9CAUL +------DLSALEARHGGRLGVSVAT--DGKQA-AWRGDERFVYCSTFKMYLAAATLLRVQ +AGQERLDRAIPVTRADMISHAPVTEPAVGSTLTIEQLMKGAVEVSDNPAANILIREMGGL +EPLRAFYRGIGDESTRVDRLEPELNVA--DDDKDTITPDQSVKNIQRLLIDTPLDTASKT +LLMRWLVDTPTGQGRIKAGVPAGWTVAHKTGTGGYGPVNDIGLILPPNGPAIAIAVYFHA +TKSTDAQREAAVADATRQALK-- +>[subseq from] class A beta-lactamase n=2 Tax=Novosphingobium sp. PhB55 TaxID=2485106 RepID=UPI001066399A +--QAASDLEEIERQHGMSIGAVMRGSDGRIHF-AHRADERFRLCSTFKIFLAAEVYRQAA +TNPHLLQRPVTIRDTDRLGNSPVTARQQDGGLSAEMLCMAAVQYSDNSAANYLLDLVGGP +PAVTRLFRTLGDNISRLDRIEPALNLGAPEDLRDTTTPAAIAGSLGTLLLSTVLGDHQRA +TLLGWMRNEQNGTRRIRAGVPRGWTVANKPGTNDAGAVNDIAIIRPPSGGSFVLTVYTAS +AENRVTQSESVIAAIAGMA---- +>[subseq from] class A beta-lactamase n=1 Tax=Legionella pneumophila TaxID=446 RepID=UPI000770A238 +---AHAGVKQIETKYNVKIGVYAIDTNNGNSF-SYRQDERFPFQSTVKMLVAAVALKNIE +-----ADERIKISSDDIVFWSPIVRLNLDRGMTIKELAEAAMRYSDNAATNILITRLGGT +KSINEFAKSIGDRSFNLENLEPNLNSD-PNNIHDSSTPKDMAQSVQKLLVNNVLGQENQN +ILKTWMMNNTTGYKKIRYGLPLGWSAAEKTGGGSV-ISNDIGIVWSPACKPIVLAIYTFS +NKKDAQKADKAIAETTKFILDEf +>[subseq from] Beta-lactamase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A2H1K923_9MICO +-qEITAQLEAVEDEYDARVGISAIDTGDGSSV-DYRSDERFGFASTLKVFAVAELLAGTS +--PEELDEVVTWTQADVDAWTPVTEKHVDTGLPLEDVAESALRVSDNAAMNIVLDEIGGP +QGLDAALEDAGDPTTEVIDEEPELNDIEPGSSDNTTTPAAYTADLQGLLDSERLSEDDRK +VLLEWMSDNETGDPLIRAGAPEGWTVKDKSGHSD-AIQNDIAFVYPPDEDPIVITVLTET +EDPESEDGPAIVEAAAEAVLGSf +>[subseq from] Beta-lactamase (Fragment) n=4 Tax=Staphylococcaceae TaxID=90964 RepID=A0A0H3W0X3_STASA +--SHTQELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQHLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPND-------------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis terrae subsp. terrae NBRC 15098 TaxID=1219058 RepID=A0A142W2H4_9SPHN +--SVANRIAALEKKSGGRLGVAVTDQFGKLIV-GHRADERFAMCSTFKLLLAAQTLTAAK +-NGVSLRTPLPFTRAELLPYSPGAERLLDAEYRIGFAAEDAVVLSDNLAANLLLDHFGGP +TAFTDHVQATGDLVTRLDRMEPDLNANIPGDPRDTTSPAAMAKSAAAYIFGDKLDTAYRT +MLRDWLVKSETGLERIRAGLPRTWPVGDKTGSCGT-AYNDVAFVEEPGGDKYMIAVYLDR +PALKGDAANAIIADVARAVT--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=A0A1E3FU98_9BURK +--TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS +LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP +QAVTAFARASGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRT +QLMEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAGLWAPSRAP--------- +----------------------- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. G0240 TaxID=2487066 RepID=A0A3N0WPD3_9FLAO +-tALEEKINSITKGKKATVGISVLGFEDHFKY-NKNGDRKLPTLSVFKFHIACAVLDFVD +KGKLSLDQRILFKKSDLLEWSPLLEKYPDGNLSLGEVIDYTVALSDNNGCDLLLRLIGGT +QTVQQFMDSKGVKGFRIKYNEDDMHKNWKTQYENYSTTNSVVDLLKKFYDGKILTKKSTD +YLMQIMLGTKTGANKIVEQLPKGTPVAHKTGSSGTVAENDMGIVTMPDGKHYAIAVFVSD +STETDSVNNKMVSDISKAVWDYf +>[subseq from] Beta-lactamase n=1 Tax=Cellvibrio sp. PSBB006 TaxID=1987723 RepID=A0A1Y0FXT0_9GAMM +-----ERLRALEVG-HARLGVCFLDTVTGEIS-GNRIEERFAMCSTFKLAMVAACLREAD +NGRLNLEEILPYSEADLLPWAPVTRKHLAKGLSIATLAQAAQEMSDGVAANLLVKRLGGP +NAVTTKFREMGDTVTRLDRYEPDLGLVLSADTRDTTSPLAYAELVRQILTGSILRRDSRE +QLLEWTRNTATGARRLRAGLPPEWRTGNKTGTGRTNKCNDVAITFPPSKNPIIIAAYFDS +GEKIEERHDAVLAEVGKIAAE-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chitinophagaceae bacterium PMP191F TaxID=1691979 RepID=UPI0006BBB2B2 +--NIRVAIANIAQAAQGKVGVAVMNLESGDTV-SLNGTVRFPMQSVFKFPIAMAVLHEVD +RGKLSLDKMIRVKKKDLMLWSPMLEKYTANEISISELLAYTVSQSDNNGCDILLKEIGGT +KKVNNYIRDLGVKGIAIKATEKEMHSAWNVQYNNWCEPIAMMQLLKIFYEGKTLLKTSND +LLWKLLVETSTGPNRLKGLLAKNITVAHKTGTSGTAATNDVGIIVLSATQHIAIAVFVSD +AEANESVRENVIAQIALLVSD-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chitinophaga oryziterrae TaxID=1031224 RepID=UPI0012F95307 +--SLRIKMGEIANTAKGTVGVAIIHLESRDTF-TLNGSLHYPMQSVYKMPLAIAVLHEVD +KGKLSLDQKIHIRKEELLPWSPIRKKYPEGNLPLREILGYTVSQSDNNGCDILFRLLGGT +ANVNKYIHSIGIDSIAIAATEEEMARTWNVQFTNWAEPGAILQLLDGIYKGKYLSKPSIS +VLKEMMEGTTTGPDRIRGILPENTVVAHKTGSSGTAATNDAGVITLPNGKHFAIVVFVCN +ATADEKRRDAVIAEITKVFWDHy +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium 13_1_20CM_4_54_11 TaxID=1805408 RepID=A0A1Q7TP74_9BACT +--DAATRIAAVEARIGGRIGVAALDTGNTKHV-EHRADERFPMCSTFKFLAAAAVMKRVD +EKKEKLERFVPYGAKEILEYAPVTKEHLKDGMTLGALCAAAIEQSDNTAGNLLLDAIGGP +SGLTNFVRSLGDRVTRLDRIEPELNSAIPGDERDTTTPAAICSDIQRLLLGDAF------ +------------------------------------------------------------ +----------------------- +>[subseq from] DNA, contig: SP630 n=3 Tax=Sphingomonas TaxID=13687 RepID=A0A0C9MTH6_SPHPI +----TARLRAIERASGGRLGAFVLDTGSGRSF-GWRADERFCHCSTFKLSLAAMALREAD +AGRLDLMETLAFSRADIVAYSPIVEENLDKGLPILALAQAVQITSDNAAANVLMHRLGGP +AALTRFWREIGDAVSRLDGYEPAINVIPPGTQENSTTPRAMAETVRRIVLGDVLRPASRD +RLRSWMAATQSGSKRIRAGLPADWHGFDKTGTGMGNKTNDLAVLMPPKGSPLVVTGYFEN +PSDVRPADEAVLKMLGRLAV--- +>[subseq from] Serine hydrolase n=1 Tax=Vibrio vulnificus TaxID=672 RepID=A0A2S3S1I9_VIBVL +--DISPKIEKLSQGLVGRVGVAAQEIGSGASI-TVNGDQTFAMASTYKVAIAVTLLDRVD +KGQIKLSDLVDLPQQEMVVTNAIAETYVHPGFSVANLIEVMITESDNTATDVSLKLAGGP +EAVTKKLRSLGITEQRVDRATSEILRAFEKDPRDHSTPKAMLQLLLAIDSGKALSAKSSQ +FLLATMSRTSTGSGRLKGLLPKGTPVAHKTGTIG-GVANDVGFITLPDGRRFAIAVFTNS +STTSAADQDRAIAEISRTLYDFf +>[subseq from] class A beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=UPI0011F3E107 +--TLQDQVKQYEKE-GWKVGLSILS-SDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD +AKKLSLNHSMVVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP +EALTEFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDASKA +QLKEWMVNNKVADNMLRASLPKRWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK +ADTSLDERSAVIRTLGSHIFDEy +>[subseq from] Beta-lactamase n=1 Tax=Ignavibacteriales bacterium TaxID=2049428 RepID=A0A419F7D5_9BACT +--------LQIIEQAKGKVGVAVINLKTSDTL-TVRGNEYFPMQSVYKFPLALAVLDKVD +KGEISLDKKLFVSKSDLLPWSPLRDKYPDGNLSLDEILSNTVSLSDNNGCDILFRLMGGT +AIVDKYIHNLGIEDIDIAFTEEEMHKDWQVQYKNRSTPLAMAELLYRFYYEDFLSKSSKD +YLWRIMAATVTGPKRIKGLLTEGTVVAHKTGSSGEDATNDAGIVQLDDGSGFVIVVFVSD +AAADEETREKVIAQIAKTVYDAy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella sp. TaxID=576 RepID=A0A346M1B8_KLESP +-----------------------------------------------------AVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVI---- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2W6WDF4_9SPHN +--------ADIEAATGGRMGIALVN-EEGRVLlGFNRAERFAMCSTFKAPLAAAVLMGAE +KKRYGMEGTLSVRQSDLLEYAPAVRANIARGMSIAELTQAVVEVSDNSAANILLPLVGGP +QGLTAFMREHGDEVTRLDRTEPSLNENAAGDERDTTSPEAMARLMADLLFADM-PQGPAG +QLRGWLQASTTGLKRIRAGLLPGWTAGDKTGTCGN-AYNDVGVLRAPDGRSYILAVYLDR +PTVPGPKAEAAIAQVTRAALA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=R4MR46_ECOLX +------------------------------------------MMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTVFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLGKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERG------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Lutibacter sp. HS1-25 TaxID=2485000 RepID=A0A4Q1IQR2_9FLAO +-kSISEKIEKISNGLVGRIGAAAQDLSTGLTV-SINGDEPFVMASTYKVAIAVTIFRQVD +EGKLKLTDLVDCPSEKMVPPNPLVTYHPGVKLSIANLLEPMITDSDNSATDFLLEVAGGP +QVVTDMLRSIGITDFRVDRYVSEILRFEQEDPRDHTTPNAMLQLLLAIDNGTALSEKSRE +VLLGMMSRTTTGFHRLRGLLPKGTPVADKTGTIG-GVANDVGFITLPDGRRIAIAVYTKS +STTSEADREKAIAEVTRSIYDFf +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. YR573 TaxID=1881040 RepID=A0A1I0PUX1_9BACT +--SLRIKIDKIANTAKGTVGVAMIHLESRDTF-TLNGNLHYPMQSVYKMPLAMAVLHEVD +KGKLSLDQKIHIRKEELLPWSPIKTKYPEGNLPLREILGYTVSQSDNNGCDILFRLLGGT +ANINKYVHRIGIDSIAIAATEEEMARAWGVQFTNWSTPGAILQLLDGIYKGKYLSKSSIA +VLKKMMQETTTGPGRIRGLLSENTVVAHKTGTSGTNATNDAGVITLPNGKHFAIVVFVCN +ATADEKTRDAVIAQITKVFWDHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A075M395_ECOLX +------------------------------------------MCSTXKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAV----------------- +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Chitinophaga sp. t5 TaxID=1461282 RepID=A0A0B5E9H0_9BACT +-----------ARGMGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEA---------------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0P0CPI6_KLEPN +-------------------------------------EGRFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWLFADK------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A3B9B4W3_9SPHN +-qDLAARISEIETASGGRLGLALHSPDKGLVY-AYRGDERFAMCSTFKLALAALTLDTPG +----LREKRLHFGAGDILSYAPYAKERASSGMSGLEAAHHAVTLSDNTAANLLLAEVGGP +DGFTRWLRSMGDETTRLDRNEPALNENAPGDPRDTTTPTAHADLVGTLLWGDRLVQADRA +LLQEWLAQTTTGMNRLRAGLPGEWRAGDKTGTCGQGEVNDIAMFETPDGARYILAAYLDR +ADGSASDAEARLAEAARAIAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Actinotalea caeni TaxID=1348467 RepID=UPI0012E14C43 +---VSAELGALEEELDARVGVSALDTGTGAVV-EHRAQERFGFASTIKVFAVAELLRRVP +--PAEREEHVTWTDADVAAYAPVTSAHPG-GLTLAQLAEAAVRESDNLATNLVLERIGGP +AGLTEALAALGDRSTRLVDVEPALNDVVPGEEANTTTPAAFTADLLAVLEPGYLTEADRD +LLLTWMSGNATGDALVRAGAPEGWEVQDKSGGAGP-MRNDVAVVTPPDGAPIVLTILTTR +NDPDAPWADELVARTAAVVLE-- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium pusillum TaxID=69373 RepID=UPI0011AB7C46 +--AVAKSLAALEHHYDATVGVVATDTTTGETV-SYNGDRRFGYASTLKAFAAAQFLRSVH +--GAARDERAHWTAEDVAAYSPVTEQHTSDGLTYSQLAEAAVRQSDNTALDLVLKRIGGP +KGLDDALTELGDATTEVVNDEPDLNTIEPASTEDTTTPAAFTADLAKVFDGRTLNATDTA +KLQDWMSGNATGDTLIRAGAPTGWTVADKSGGAG-GIRNDIARVTTTDGHDIVISVLTTK +NDPAAKYDDALVAESAKTVLPAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. t1 ZQ-2014 TaxID=1561000 RepID=A0A0B5E3C6_9PSED +------------RRMGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEA---------------------------------------------------- +----------------------- +>[subseq from] CP254 BETA-LACTAMASE n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0000110576 +-kNAAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPK------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Listeria aquatica FSL S10-1188 TaxID=1265818 RepID=W7B1Z1_9LIST +--SVSEKLEVLENKYNAKLGVYATD--GNEKI-KYHSRERFAYTSTYKAIISGLLLKNRT +--EEELQKTIFFSKEDLVDYSPITEQFVDKGMTLKEIIHAAVAYSDNTAGNLLLNEMGGT +KKFQKELRLIGDKTTISSRYETDLNSAIPGDIRDTTTPEAFGQDLKYLTDPKHLDSQALK +YFKQTLVDNTTGDNLIRAGVPDGYLVGDKTGAGSYGTRNDIAIIFKENSKPLVWTVFSKM +DKEDDSYNDQLIADVAKVLSEEf +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. CF314 TaxID=1144316 RepID=J2K7P7_9FLAO +-sALDQKINSIIKDKKGTVGVSVLGFENEFTY-NKNGDKKLPMQSVFKFHIAAAVLDFVD +KGKLSLDQKIFVKKSDLLDWSPLREKYPAGNLPLSEIIDFTVAQSDNNGCDILLKLIGGT +STVQKFMDSKGVKGFQIKFNEEEMHKDWNAQYENYSTTGSIVQVLKKFYDGKLLSGKSTE +YLMKVMLGTKTGTNKLVEQLPKGTPVAHKTGSSGTGAENDMGIVTLPDGKHYAIAVFVSN +STETDAINCKIISDVSKTVWEYf +>[subseq from] Beta-lactamase n=2 Tax=Pedobacter bauzanensis TaxID=653929 RepID=A0A4R1LNQ8_9SPHI +---LRQQIEQILISKKATVGVAVFGFEKGDTL-SVNNQIHYPLQSVFKFHIALAVLDKVD +KGELSLNQKILIKKSDLLPWSPIRDDYPNGNLTIAKILEYTIAQSDNNGCDILLRLIGGA +EVVNNYIHKIGVKDFSIQVNEEDMHREWNIQFLNWTTPTSTIDVLRKFNTGNILSKESYD +FLWNTMVETKTGEKRIKGKLPTGTVVAHKTGTSGTAAINDVGIVVLPTGEKVAISVLVSN +SKESQEVNEEIIADVSKLVWDWf +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga polysaccharea TaxID=1293035 RepID=A0A561P723_9BACT +hpTLRQQIADIAGNISGKVGVYAQLLETNDTV-SFNRDQHFPMQSVYKFPVSMAVLQQVD +AGKVGLDQPVDINKTDLTTVSPLRDKYPDGNLTVRELLDYNVRKSDGSACDILFKLLGGP +EKVNAYVHGLGIRSINIATLEEAQKENLQVQYRNWSTPAAMVQLLKKFFQDPVLSDSSKE +HLLYLMTTSGPGAKRLKGLLPEGTEVAHKTGTSWTAANNDVGIITLPNGTHMAIAVFVSD +SKANDEERDATIAKIAKAVWDSw +>[subseq from] Class A beta-lactamase n=2 Tax=Siphonobacter curvatus TaxID=2094562 RepID=A0A2S7ILX8_9BACT +-sSLRKAIQQIAQSSGGTVGVSIIHLERGDTL-SLNGTGHFPMLSVYKFPIAIALLNQIE +AGKFDLDTKWHVTKKELLSHSPIRDKYPQGNITIRELIENMVALSDNNACDIILRKLGGT +KVVENYFHHLGYKNIAIRATEEEMATEWSVQYQNWCEPVLMGRLLNDFYEGKLLNSAYTK +VLKDIMLSTSTAPNRLPGLLPKGTPIARKTGTSGTAATNDVGVITLPSGQHLVVAVFVMD +SKAETAVREQTIARIAKAAYDHy +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium iliopiscarium TaxID=56192 RepID=UPI0005D353E2 +--DIDQYLRDTEQQIQGQIGVAVIDTQNNTQW-NFNGSERFPMMSVFKTLACANVLYDVQ +HKALKLTDKIDVTKAGLINWNPITQNFVGGKMSLQSVCGAAMLMSDNYAANLALEKIGGP +QGLTAFLRTIGDNSTLLDHFEPKLNYVEKGAKNDTTTPIAMMNTVKKLLIGNVLNAENKA +QLQFWMTNNMVSDGLARAVLPQGWKIADRSGGGVNGSRTLTAMVWNKDHQPVFIGIFIAN +SKKTLPELNKVMVAISEKIFHQy +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0010BE0298 +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMQRNTTGDNLIRAGVPGGWEVADKT------------------------------ +----------------------- +>[subseq from] Beta-lactamase TEM-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2L1K688_KLEPN +------------------------------------------------------------ +-------------KNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVTGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Filimonas lacunae TaxID=477680 RepID=A0A173MBB3_9BACT +-nTIHKEVSHIVATQHGKVGFYATVIETGDTA-SYNSNNKFPMQSVYKFPIAMAVLKQVD +EGKLSLQQQIHILPSDIMPHSPIREKYPQGNMTLDQIITYNVQESDGTACDVLLRILGGT +AKANAYIQKLGIKNINIATTEKAQQTNDMVQYKNWSTPKAMTTLLKQFYTKPILSAGSKA +YLLKLMIETPHGAQRLKGKLPAGTIVAHKTGTSGTRATNDAGIITLPNGNHIAITVFVSD +SEDSQEQREGTIAAVAQAAWNQw +>[subseq from] Uncharacterized protein n=2 Tax=Legionella TaxID=445 RepID=G9EPC1_9GAMM +---AHAGVKQIETKYNVKIGVYAIDTNNGNSF-SYRQDERFPFQSTVKMLVAAVALKNIE +-----ADERIKISSDDIVFWSPIVRLNLDRGMTIKELAEAAMRYSDNAATNILITRLGGT +KSINEFAKSIGDRSFNLENLEPNLNSD-PNNIHDSSTPKDMAQSVQKLLENNVLGQENQN +ILKTWMMNNTTGYKKIRYGLPLGWSAAEKTGGGSV-ISNDIGIVWSPACKPIVLAIYTFS +NKKDAQKADKAIAETTKFILDEf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sphingomonadales bacterium TaxID=1978525 RepID=A0A4Q3C4T7_9SPHN +----------------------------------HRAQERFAMASTFKWLLAAGVLKRCE +-EGLNIDAVMYFTPSDLVATSPVTSAQIGAALSVEQLCDAIVTVSDNTAANLLLVPMFGP +EGLTRFLRESGDAHTRLDRQEPELNENKANDPRDTTVPHAMARTLRRLLTDEVLNADSRA +RLIGWMEKASTGLDRLRAGLPVGWRAGDKTGTGGNGAHNDCCIVWPPGRSPIVIASYLSE +SSAPNTDKAAAHAAIARIIVEEf +>[subseq from] Class A beta-lactamase n=1 Tax=Nostocales cyanobacterium HT-58-2 TaxID=1940762 RepID=A0A1Y0RUL5_9CYAN +--RLHSQIEQISRAAQGRVGVAITLLETGESV-ALKANEQFPMQSVYKLPIGMAVMHQVD +QGMLKLGQKVQVTRNDFVTHSPIRDNHPQGVLNVLDLLRFMVSESDGTACDVLLRLIGGP +QFVTKYLHELGINGIVVANTEKELGQNELVQYRNSATPESVIVLLSALHAGRGLRESSRA +LLLQLMTQTPTGPRRIKGLLPVGTVVAHKTGSSRTAATNDVGLVTLPNGRHIAVAVFVSD +SKADDSTREKVIAMVARAAWDYw +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudarthrobacter sp. NamE5 TaxID=2576839 RepID=A0A5C4INA2_9MICC +--HLDRSIAALESANGVTIGIAAGR--QGQTAyTYRGGDTFPMCSLFKTLAVARLLREHT +YDDEFWKRRIRFRDDQIVENSIICAADEDRDMSVEELAEAALRFSDNTAGNLLLELIGGP +LQIGAYARTLGAPSTRLDRWEPELNEALPGDLRDTSTPSDIHKLYEALLLGEALGTLGQA +RLRSWMLRNTTAGKRLGAAVPPGAELADKTGAGAYGVVNDAGVVWPDGRPPLTLAVMTKT +DDPDAVNNNAVLARVGQLVFA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC52_STAAU +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPND-------------- +>[subseq from] Class A beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=I3NNU9_9BACT +---AHAGVKQIETKYNVKIGVYAIDTNNGNSF-SYRQDERFPFQSTVKMVVAAAALKNIE +-----ADERIKISSDDIVFWSPIVRLNLDRGMTIKELAEAAMSYSDNAATNILITRLGGT +KSINEFAKSIGNASFYLENLEPNLNSD-PNNIHDSSTPKDMAQSVQKLLENNVLSQENQH +ILKTWMMNNTTGYKKIRYGLPLGWSAAEKTGGGS-GTSHDIGIVWSPACKPIVLAIYTFS +NKDNAQQADKAIAETTKFILDEf +>[subseq from] Beta-lactamase n=1 Tax=Providencia alcalifaciens TaxID=126385 RepID=A0A4V6P077_9GAMM +--TLQDQVKQYEKE-GWKVGLSII-FPDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD +AKKLSLNHSMIVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP +EALTAFMRAIGDTVTRSDRYEPELTVNPEGDLRDTTTPDAMSKSIKKILTGEVLSNSSKE +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK +ADTSLDERSEVIRVLGSHIFDEy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium AOCarb3 TaxID=654974 RepID=D6MLV4_9BACT +-kDVKDKIEQIIDRSNGNIGVGVFDFASGLTV-LINNAHQFPMQSVFKFPLGMAVLDMVD +RGKLKLDQQVYVSKNDLQPYSPLRDKFPDGNVTLADLLTYSVSLSDNNACDILFRLVGGT +QVVNDYIRGLGIKDMAIVATEMQMSKGWDVQFENYSTPEAMLDLLKVFQSGKKLSASSSG +FLWKIMTESPTGLKRIKGKLPSTAKVTHKTGTSGTAATNDVGIMTLPNGNQIAIVVFVSN +SEANETAREMVIADIAKVTWDEf +>[subseq from] Class A beta-lactamase n=2 Tax=unclassified Siphonobacter TaxID=2635712 RepID=A0A2N7BCP2_9BACT +-sSLRKAIQQIAQSSGGTVGVSIIHLERGDTL-SLNGTGHFPMLSVYKFPIAIALLNQIE +AGKFDLDTKWHITKNELLPHSPLRDKYPQGNLTIRELMENMVALSDNNACDIILRKLGGT +KVVEAYFHRLGYKNMTIRATEEEMATEWSVQYQNWCEPVLMGRLLNDFYQGKRLNSAYTK +VLKDMMLSTSTAPNRLPGSLPKGTPIARKTGTSGTAATNDVGVITLPSGQHLIVAVFVMD +SKAETAVREQTIARIAKAAYDHy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Hymenobacter sp. Fur1 TaxID=2594794 RepID=A0A558BPJ7_9MICO +--ALQAEVARAVAGFAGTVGVAVQEVETGASA-QVNGQAHLPMQSVYKFPLALAVLHQVE +LGRLQLDQELLLRPADLLPWSPLRERYPAGNVPLREVLRYTVSESDNNGCDILFRLLGGP +AAVQAYVRSLGVADVHIAATEEEMHRREDVQYTNWATPAAMCQLFANFSRGRYLAPASRA +VLWQMLATSPSGLKRLRAGVPAGTEVAHKTGTSGTAATNDAGLLTLPNGQHVAVVVFVTN +ATAPEEASESLIAAVSRVVWRHf +>[subseq from] class A beta-lactamase n=1 Tax=Nostocales cyanobacterium HT-58-2 TaxID=1940762 RepID=UPI000B3C4623 +--RLHSQIEQISRAAQGRVGVAITLLETGESV-ALKANEQFPMQSVYKLPIGMAVMHQVD +QGMLKLGQKVQVTRNDFVTHSPIRDNHPQGVLNVLDLLRFMVSESDGTACDVLLRLIGGP +QFVTKYLHELGINGIVVANTEKELGQNELVQYRNSATPESVIVLLSALHAGRGLRESSRA +LLLQLMTQTPTGPRRIKGLLPVGTVVAHKTGSSRTAATNDVGLVTLPNGRHIAVAVFVSD +SKADDSTREKVIAMVARAAWDYw +>[subseq from] class A beta-lactamase n=1 Tax=Microbacterium sp. 3J1 TaxID=861269 RepID=UPI000B8156FB +-----KRISELEKSSEVTIGVVAGD-GTRARI-EHRADELFPMCSLFKTLLVAELLERHS +YDSAFWSKTITFTPDDIVVNSLITAADPDGQMTIDELADAALRYSDNTAGNLLLREVGGP +SGLTSTLRRVGAQWTRLDRWEPELNEATADDPRDTSTPREIHRLFSDALIGSRLDQLGRA +RLMSWMLQNQTTSTRIGAALPEGAELADKTGAGGYGVVNDAGVVFLENRA-VSLAILTRT +SDSSAVGNNDVVRDTARIVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFE76E1 +----NDSFAKLEKEFDAKLGIYALDTDTNQTA-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD +LLIDWMKRNNTGDNLIRAGVPGGWEVAD-------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. 66-10 TaxID=1895848 RepID=A0A1M2ZGS8_9SPHN +-qAVAAQVAALEKQIKGRVGVAFRLLETGESG-AVAGAERFPMASTYKVAIAGTLLSLVD +KGQMRLDRMIAVTQADVDQTGEVANRVVHPGLSVANLMELMLTQSNNTATDKILALAGGP +AAVTAWLRANGIAEMQVDRSVNDLLNAFEKDPRDTSAPVAMVDLLGKLLASPLLKPESRD +FLRSVMERCETGAARIKGLLPAGTTVAHKTGTIG-GSINDVGMITLPDRGHLLIAVYTKS +SSLPEAQRERAIAEISRSLFDYf +>[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis lucentensis TaxID=53441 RepID=UPI000A003F43 +----DAEFTRLEEEFGVRLGVHALDTGTGRTV-EFQADERFAHCSTYKVLAFGAVLDRTP +--VDGLDRVVTFSGADLVFHSPIAQERVSTGMTLRELGDAALRHSDNTAANLLLRELGGP +EGLTEALRGIGDEVTRVDRFAPGMAEAVPGDVRDSSTPRALATSLRAFALGEVLPEDRRD +VLVGMLRANTTGDDLIRAGAPEGWEVGDKTGACGYGTRHDI------------------- +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Citrobacter freundii TaxID=546 RepID=G3LSZ7_CITFR +-----------------------------------------PMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNHIA------------------ +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q5WJ47_9BURK +------RLQALESASGGRLGVAVQEAGRAAPW-GYRQDERFPMCSTFKLIAAAGVLAMSA +RDAGLLERRIAYTQADLVSYSPVTQKHVGDGMTVAGLCAAALQYSDNTAGNLLIRLLGGT +DAVTAYARGIGDSAFRLDRWETELNTAIPGDPRDTTTPAAMATSVQRLALGDALGAPQRA +QLVAWLRGNTTGATRIRAGV---------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1D5 TaxID=2080546 RepID=UPI000CE780BD +---VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKSLAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDSTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLVAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Mucilaginibacter limnophilus TaxID=1932778 RepID=A0A437MFX8_9SPHI +-qDLRSKIIYIATQINGVVSVSVTNLETGDTL-NYNGNSHMVMHSVMKLPIAMTVLHQVD +KGKLKFDQKIHITKADLPEYSPLRDKYPEGDIAVSQLLSYMVSLSDNDACDILLKVLGGT +ATVEKYVHSIGVKDISIKASEAQMASAWPVQYTNWCSAKAINQLLGIMYKGSALSKRSND +FLWKIMLETSTGPKRLKGLLPNDAKVVHKTGTSPAAATNDAGIMILPNGRHIAISVFITD +SYADNAKRESVIAQIAKAVWDEy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus intermedius TaxID=1285 RepID=A6MFN9_STAIN +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKVITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPND-------------- +>[subseq from] class A beta-lactamase n=1 Tax=Providencia sp. wls1921 TaxID=2675153 RepID=UPI0012B57A5E +--TLQDQVKQYEKE-GWKVGLSII-FPDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD +AKKLSLNHSMIVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFTIFSGGGP +EALTAFMRAIGDTVTRSDRYEPELTVNPEGDLRDTTTPDAMSKSIKKILTGEVLSHSSKE +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK +ADTSLDERSEVIRILGSHIFDEy +>[subseq from] class A beta-lactamase n=2 Tax=Morganellaceae TaxID=1903414 RepID=UPI0003E2A204 +--TLQDQVKQYEKE-GWKVGLSII-FPDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD +AKKLSLNHSMIVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP +EALTAFMRAIGDTVTRSDRYEPELTVNPEGDLRDTTTPDAMSKSIKKILTGEVLSHSSKE +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK +ADTSLDERSEVIRILGSHIFDEy +>[subseq from] Beta-lactamase n=1 Tax=Cellulomonas bogoriensis 69B4 = DSM 16987 TaxID=1386082 RepID=A0A0A0C0J0_9CELL +--DVSAELQRLEEEFDARVGVSAVDTGTGTTV-EHRAQERFGFASTLKLFAAAELLRQVP +--VDQRDARVTWTQEDVRAYSPTAGQHVADGLTLAELAEAAVRESDNTAMNLVLRALGGP +EGMERALADLGDSTTRVVDVEPGINDADLASGANTTTPRAFTANLRALLEPQNLREEDLA +LLLDWMTGNATGDALVRAGAPAGWVVTDKSGGAG-GIRNDVAVVLPPGRDPVLVTILTEK +RAPGAAYDDALVSRTAATVLSAf +>[subseq from] Class A beta-lactamase n=1 Tax=Ponticaulis sp. TaxID=2020902 RepID=A0A2D6GUS1_9RHOB +----HTAIAYMESQNGGRFGVSAVNLATGQTI-THRGDERFAMCSSFKWLLAALVLQRVQ +AGEEDLSRMIEFSEADMVMHAPITEPALGEGLSVEALCRGTVQTSDNPAANLLLRTLGGP +EGFTQILRDNGEMTTRLDRWEPMLNENAAGDPQDTSTPNAMVSLMGYYLFGGGLNAEYQT +LLKDWMIGATTGLARLRDGMDAPWIGGDKTGTSSNNQSNDVAFAYQPDADPILITSYLNV +ENPVGAETDELHATIGRQIM--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A2Z6A9I1_SHISO +------------------------------------------MMSTFKVLLCGAELSRVD +AEQEQLGRRIHYSQNDLVEYSPVTEKHLTAGMTVRKLCSAAITMSDTTAAKLILTTIRGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTPASRQ +QLIDWMEAVKVPGPLLRSALPAGWFIADNSGAGERGSRGIIAALGPDGKPSRIVVIYTTV +SQA-------------------- +>[subseq from] Beta-lactamase n=1 Tax=Ignavibacteriae bacterium HGW-Ignavibacteriae-2 TaxID=2013809 RepID=A0A2N1VRQ4_9BACT +----RTNIKNIINNTNGSVGTAIFNLENGDTL-TFNGEAHFPMQSVYKFPLALAVLNEID +KGAFSLEQKIYVSKNDLLPWSPLRDKYPNGNIAISELLTYTVSQSDNNGCDILFRLIGGP +AKVNEYVHSLGIEGINIVSTEEEMHKDGTLQYKNWTTPKAMGQLLIKFVKESIISTKSKD +FLWDVMASTVTGKGRIKGLLPEGTIVAHKTGSSGAAATNDVGIIKLPGGGDLVVVVLVSD +CKDDEKTRDKIIADIARLAWE-- +>[subseq from] Beta-lactamase n=1 Tax=Siphonobacter aquaeclarae TaxID=563176 RepID=A0A1G9Q6P3_9BACT +--SLRTELVRIAEASRGVTGIAVTQLETGDTL-SVRGREHFPMQSVFKFPLALAILDLAD +KGRLSLDKTVRVLPNDLVPYSPLREAYPNGNITIAELLRYSVSLSDNIACDLLFRELGGP +DKLEKYLRKLGLTGISVKATEAQMATGWNVQYTNWCEPKTMNDLLVRFFTGKILGTASTE +RLRKWMLDTPTGSARLKGRLPAGTPVVHKTGTSSTNATNDAGVITLPGGGHVAVTVFVSD +SSAGLKDREETIARVALAVYQHy +>[subseq from] class A beta-lactamase n=1 Tax=Roseibium sp. RKSG952 TaxID=2529384 RepID=UPI0012BCD603 +---LASAITNMEQREGARIGVSVLDTQSGDVF-NHRGDERFPLNSTFKAFACGALLQKAQ +NGGIDLDARRPVSEQEVVSWSPVTEKQIGAPLTFREHCKASLEWSDNTAANVVLEAVGGP +KAMTQVLRTFGDTTTRIDRFEPDANIQPEGEVRDTTTPKAALQSFKTFVADGVLSGGVHA +DYLDWMKSGQVTGALLRPHLPEAWEIADRSGAGRDKTRSVIAAIWPPESAPVYVAIYIDL +EAASMQRRNEMIAELAQTLFQ-- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus stepanovicii TaxID=643214 RepID=A0A239Y773_9STAP +--RTKQDLKMIEDKYDANVGVYALNTATGEEI-KFNENKRFAYASTLKAISSALLLEKTP +--HNKLNKKIHISKKQIVSYSPILEKYIDKDITIKKLIEATMLYSDNTANNIIIDELGGY +KEMRKRLKKLNDSTTVLSRKEPDLNNYSPKNTSDTSTPQAFGKTLKKLVMDGDLSKDNKE +FLLKLMINNKNGDTLINAGAPKTFKVADKSGQATYGSRNDVAFVYPKGHKPIILVIFTNK +NNKDAKPNDKVVSDVAELVL--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. CRIBSB TaxID=2683264 RepID=UPI001412EC88 +-----VDFSALEARHGGRLGLYAV--GDAGAV-EWRGGERFVYCSTFKMYLAAATLLRVQ +AGQEQLDRQIPITRADMINHAPVTEPAVGGSLSIEQLMKGTVEVSDNPAANLLLKALGGL +EAMQAFYRSLGDNSTRVDRFEPEMNRL-DGD-KDTITPQSVANMLRLFIRPDTLSADSKA +MLLGWMFTSPTGVGRIRAGVPAGWRVAHKTGTGGYGPTNDIGALYPPTGGPITIAIYYHG +VRASDEQNEAVIAEATRMTL--- +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium pusillum TaxID=69373 RepID=UPI00119D5CAA +--AVTGALAALEHEYDATVGVVATDTTTGDTV-SYRGDRRFGYASTIKVFAAAQFLRTVR +--GHARDARVHWTVDDVAAHSPVTGAHVADGLTLAQLAEAAVRQSDNTALNVVLEHIGGP +ASLGAALRDLGDRTTEVVHDEPALNMIEPGSTEDTTTAAASTASLARVLDGRTLGPADTA +LLEAWMSGNATGDTLVRAGAPTGWTVADKSGGAG-GIRDDVALVTRPDGDPIVISVLTTR +NQPGTPYDDALVAETAHAVLGAf +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium daecheongense TaxID=192389 RepID=A0A3N0W4X7_9FLAO +---LEQKINTILKDKKATVGISVLGIENGFQY-QKNGEKKLPMQSVFKFHIACAVLELVD +KGRLSLDQKILVKKSDLLEWSPMRDKYPNGDLTLGEIIDYTVAMSDNNGCDILLRLIGGT +KTVQKFMDSKRVTGFQIKFNEEEMHKDWNAQYENYSTTHSIVQVLKKFYNGKLLSKKSTD +YLMNVMLGTKTGTNKMVEQLPKGTPVAHKTGASGTGAENDMGIVTLPNGKHFAIAVFVSN +STETDAVNCKIVSDVTKVVWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas bogoriensis TaxID=301388 RepID=UPI00054CF24D +--DVSAELQRLEEEFDARVGVSAVDTGTGTTV-EHRAQERFGFASTLKLFAAAELLRQVP +--VDQRDARVTWTQEDVRAYSPTAGQHVADGLTLAELAEAAVRESDNTAMNLVLRALGGP +EGMERALADLGDSTTRVVDVEPGINDADLASGANTTTPRAFTANLRALLEPQNLREEDLA +LLLDWMTGNATGDALVRAGAPAGWVVTDKSGGAG-GIRNDVAVVLPPGRDPVLVTILTEK +RAPGAAYDDALVSRTAATVLSAf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. TaxID=239 RepID=A0A519STE9_FLASP +--NLQPTLQRIADKYTATIGFSALDLENGKIY-SVNGNKHLPMQSVYKFHLALAVLSQVD +QGTYKLDEKIHIKQSDLLPHSPLREKYPNGDISLAELLTYTVGQSDNNGCDILFRLLGGP +AKVNSFIHMLGVQHVEIVATEEEMHKNEKVQFTNWTTPDAAIQLLNMFYKKKILSEQLHA +FLWKVMTESASGPKKIKGQLPEGTLVAHKTGYSGTAASNDIGIVTMPNGKHFAIAAFISN +TKENEEVIDRIIAELTRAVWDEf +>[subseq from] Class A beta-lactamase n=1 Tax=Cellvibrio sp. PSBB023 TaxID=1945512 RepID=A0A1U9N8U3_9GAMM +--------------GQARLGVCFLDTVTGEVS-GNRIEERFAMCSSFKLAMVAACLREAD +NGRLSLDEILPYSAADLLPWAPVTREHLAKGLSIATLAQAAQEKSDGVAANLLVKRLGGP +KAVTAKFREMGDTVTRLDRYEPDLGLVLSADTRDTTSPLAYAQLVSRILTGSILRPDSRE +RLLEWARNTTTGARRLRAGLPTEWRTGNKTGTGRTNKCNDVAITFPPGKNPIIIAAYFDS +GEKIEARHEAVLAEVGKIAAE-- +>[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. 314Chir4.1 TaxID=1279028 RepID=A0A285XX17_9MICO +--AVARSLAALEREYDATVGVVATDTTTGATI-SYNGDRRFGYASTLKAFAAAQFLRSVH +--GAARVERVHWTAADVTAHSPVTEQHIPDGLTYTELVDAAVRQSDNTALNLVLTRIGGP +KGLDDALAALGDTTTEVVNDEPDLNTIEPGSTEDTTTPAAFTADLARVFDGHTLNASDTA +QLRDWMSGNATGDTLIRAGAPTGWAVADKSGGAG-GIRNDIARVTTTDGNEITISVLTTK +HDPAAAYDDALVARSAAAVLRAf +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas acidaminiphila TaxID=128780 RepID=A0A0S1AYP8_9GAMM +--ALQAEAERLAAQLPGDVGAALVHLESGRAV-YLNADQPLPMASTMKVPVAVHILKLVD +EGKLSLQQQVLLGPEDIYPGGPM-DTHLSAGITIRDLLHMMITVSDNNATDILVRTGGGP +EAVQQRMRALGVDGLRVDRYIWELLAAWNADPRDTSSARAMAQLLQRTWKGEILSPASTA +VLQQIMLDTRTGSARLRGMLPSGTPVAHKTGTVGD-VINDVGVIELPNGRGHVVAAVFIR +SRASSEARDAAIAQLARAAHDYy +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=root TaxID=1 RepID=A0A0B5E4A9_9BACT +--------------MGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEA---------------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. C-1 TaxID=262667 RepID=A0A0M8JGW8_9SPHN +----AKAIRDVERRSGGRLGIAVVD-ARGKLVsADRGHERFAMCSTFKLLLAGQVFERAA +-EGVSLRTPLPFERGELVSYSPGTEKLIGPDQRLGFAARDAVVLSDNMAANLILEQIGGP +AAFTAALRRSGDAVTRLDRIEPDLNENAPGDERDTTSPIAMATSAAAYIYGSRLKPDHRT +QLRGWMIESATGLKRIRAGLPQGWIAGDKTGTCGT-AYNDVAFVETPGGRKYVIAIYLDR +PAVEGDVASAVIAEATRIVA--- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=2 Tax=Chryseobacterium TaxID=59732 RepID=A0A376DT02_9FLAO +-sALEQKINAITEGKKATVGVSVLGFENNFKY-HKNGDKPLPTLSVFKFHIACAVLDLVD +KGKLSLDQNIFFKKEDMLPWSPIGKKYPEGNIPLGEVLDYTVAQSDNNGCDMLLKLIGGT +KTVQNFMDSKGVKGFQIKRNEDDMHKNWKTQYDNYSTPNSAVLVLKKFYDGKLLSKKSTD +YLMKIMIGTTTGTNKIVEQLPKNTPVAHKTGSSGYNAENDMGIITLPNGKHYAIAVFVSN +STETDAVNCKVVSDISKAVWDDf +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga pinensis TaxID=79329 RepID=A0A561J112_9BACT +--TLRKTIDSIATHSKAHIGVSALLLETGDTL-TYRGNDHYPMQSVYKFPISMAMLHQVD +LGKYKLDENITITNDDIMPHSPIREAHPHGGMTVREISRYNIQESDGTACDVLLRLLGGT +KKTDAYIKSLGVKGINIATTEKEQQQDDTTQYRNWATPVGMTQLYKVFYQGKVLSKQSYD +VLWKDMAGSFPGAKRIKGLLPAGTVVAHKTGTSGTAATNDSGIIILPNGKHLALAVFVSD +SKGSEAEREGWIAQISKAVYDHf +>[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=UPI001261CA0B +---VETEVARLATLVDGKVGVSAWRLDKGAQV-HLNPDEAFPMASTFKVAVAAVILTKVD +AGELALTTMVPVPKAFYVDSEVVADRFIHDGLSVHNLLEVMLTQSDNTATDVLVAQAGGP +AAVTAWLRAQGIEGQRLDRNTRQLLSAFDKDPRDTSTPRAMSTLLTKLFTGKALSPASTE +VLVQIMERCRTCSARLRGSLPPGTKVADKSGTVA-GTVNDVGVVTLPDGSQFAISVFVKA +SNAPRSERERVIAEIARTVRDFy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Spirosoma rigui TaxID=564064 RepID=UPI0009B051D2 +---LQTQIERLINGRKATVGVSIHEFGSQQTL-VINGDKQMPMQSVYKLHLALAVLNEVD +KGRFTLTQKMHVKKSDLIPHSPMGEDYPNGGLPLADIIRYMVADSDGSACDYLFRLLGGP +GKVNDFIHHLGITDVAIQNTEEMMQANWAVQYTNWTTPKAMLRLLELIYQRKILSPARHD +FLWKVMVGTTTGENRLKKLLPPGTVVAHKTGTSGTGAVNDVGFIALPNGRYMAISVFVMN +STESMETNERIIADIAKVAYDHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A077D1U6_ECOLX +------------------------------------------MCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVHYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIA------------------ +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Oxalobacteraceae bacterium TaxID=1871070 RepID=A0A4Q3LMY0_9BURK +------QLRALEQNANGRLGAYVVDIERGTAF-GWRENERFTHASSFKMSLAAMLLAKAD +AGKIDLRETLHWTKEDMLSVSPVTTANLGKGLSVRDLARATLVTSDNTAANVLMRRFGGP +SELTAFWRSIGDKSSRLDRYEPELNVTPPGTDLDTTTPAAMAATTAAFVHGTILTADSRA +VLRAWMAEVKTGQDRIRSGFPTNWISGDKTGTGIKHIYVDLAFGGPGGRSPLIVTAYFEP +SRPMDRDAVAVLAAVGRIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas acidaminiphila TaxID=128780 RepID=UPI00137604D6 +--ALQAEAERLAAQLPGDVGVALVHLQSGRAV-YLNADQPLPMASTMKVPVAVHILKLVD +EGKLGLQQQILLGPDDIYPGGPM-DTHLSAGITIRDLLHMMITVSDNNATDILVRTGGGP +EAVQQRMRALGVEGLRVDRYIWELLAAWNADPRDTSSARAMAQLLQRTWKGEVLSPQSTR +VLQQIMLDTRTGSARLRGMLPSGTPVAHKTGTVGD-VINDVGVIELPNGRGQVVAAVFIR +SRASTEARDAAIAQLARAAHDYf +>[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas sp. IC4_254 TaxID=2714040 RepID=UPI00142271E4 +---VEVGLAALEESTGRRVGVYARDTGSGDTV-AYRADERFGYASTLKALAAGEVLAGQP +--ASVLDQPLTVLPEDVADHAPVTAGAAGTDLTIGALGAAAVTDSDNGALNVLLRHLGGP +AALQAALAARGDTTTLVDADEPGLNEFTPGDPARTSTPRALAEGLATYVLGDALDPGVRA +AYVGWLTASTTGLDAIRAGTPEGWTVGDKTGTAGYGSRNDLAVVWPPGREPIVLAVLTDH +PDEAAEPDDAVLAAAARVVLAAy +>[subseq from] Class A beta-lactamase n=1 Tax=bacterium TaxID=1869227 RepID=A0A2W4RYB6_9BACT +-eRLEREIARLAELAGGTVGVAAVHLETGRAV-YLNRTERFPMASAYKVPIAVELLTRVD +RGEVRLDSLIEIRPEDLHPGSGTLTSLFDDPLSVHNLLELMLLISDNSATDILLRLAGGA +EAVTARMRAVGAEGIRVDRPTSLLIGAFDADPRDTATPEAMARLLERIWRREILSAESTE +LLLDIMRRCETGEGRIKGMLPPWVEVAHKTGTIG-GTTNDVGIISLPDAGHVVTVVFIKE +SQRPIPERERAIAFIARAIYDDf +>[subseq from] Beta-lactamase n=1 Tax=Parapedobacter composti TaxID=623281 RepID=A0A1I1LXN7_9SPHI +-qSIRQHIAQIIHSKNAVVGVAITSADGQDTL-SINGAKRFPMQSVFKFPIALAMLSEID +KGNFSLDQKVEIKKSELLPYSPIREAYPEGTLTIAEILQYTVSLSDNVGCDVLLRLLGEP +EAVERYLKAHNIKDISIKINEEIMQSDWESQFRNWTTPVEANRILQTYYEGNLLSPASHR +FIWDLMKGTETGRNRLKGRLPEGTVVAHKTGWSGTAAVNDVGVVFMPDGNHFYISVFVTA +SSEDMETNERIIADITKAAWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. B18 TaxID=95614 RepID=UPI0003467E2E +--AVDRTLAGLEREYDATVGVVATDTTTGETV-AYGGDRRFGYASTLKVFAAAAFLRQVH +--GADRDERVRWTAADATAHTPVTSAHVADGLTLAQLAEAAVRQSDNLALNLVLDRIGGP +AGLGRALTELGDRTTEVVHDEPSLNTIEPGSTADTTTPAAFAADLATVLDGRTLGRSDTA +LLERWISGNATGDTLVRAGAPAGWTVADKSGGAG-GIRNDVARVTRPDGGPIVIAVLTAR +NEPDAAYDDALVARSARAVLAAf +>[subseq from] Uncharacterized protein n=1 Tax=Stenotrophomonas acidaminiphila TaxID=128780 RepID=A0A2L0SPR8_9GAMM +--ALQAEAERLAAQLPGNVGVALVHLQSGRAV-YLNADQPLPMASTMKVPVAVHILKLVD +EGKLGLQQQVLLGPDDIYPGGPM-DTHLSAGITIRDLLHMMITVSDNNATDILVRTGGGP +EAVQQRMRALGVEGLRVDRYIWELLAAWNADPRDTSSARAMAQLLQRTWKGEVLSPQSTR +VLQQIMLDTRTGSARLRGMLPSGTPVAHKTGTVGD-VINDVGVIELPNGRGQVVAAVFIR +SRASTEARDAAIAQLARAAHDYf +>[subseq from] class A beta-lactamase n=1 Tax=Providencia alcalifaciens TaxID=126385 RepID=UPI000D34483C +--TLQDQVKQYEKE-GWKVGLSII-FPDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD +AKKLSLSHSMIVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP +EALTAFMRAIGDTVTRSDRYEPELTVNPEGDLRDTTTPDAMSKSIKKILTGEVLSHSSKE +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK +ADTSLDERSEVIRVLGSHIFDEy +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A246HKD6_STEMA +---VETEVARLATLIDGKVGVSAWRLDKGEQV-HLNPDEGFPMASTFKVAVAAVILTKVD +AGELTLTTMVPVPKSFYVDSEVIADRFIHDGLSVHNLLEVMLTQSDNTATDVLVAQAGGP +AAVTAWLRAQGIEGQRLDRNTRQLLSAFDKDPRDTSTPRAMSTLLTKLFTGKALSPASTE +VLVQIMERCRTCSARLRGSLPPGTKVADKSGTVA-GTVNDVGVVTLPDGSQFAISVFVKA +SNAPRSERERVIAEIARTVRDFy +>[subseq from] Class A beta-lactamase n=1 Tax=Siphonobacter curvatus TaxID=2094562 RepID=A0A2S7IFI9_9BACT +--PLQTQIEQLLQGKKATVGVGIYDFNTKQTV-FLNGDTHLPMQSVYKFHVALTVLKEVD +KGRFKLDQKMHVKKSDIVPHSPMGEDHPNADLPLSEIIRYMVAESDGSACDYLFRLLGGP +TNVNTFIHQLGIKEVAIRETEETMQANWDVQYTNWTTPAAMLDLLKLFYQQKILSKGSHD +FLWKVMTGTVTGENRLKKLLPAGTLVTHKTGTSGMGAVNDVGFIALPNGKHIAISVFVAN +STEGIDKNEQIIADIAKLAYDHf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Pedobacter sp. HMWF019 TaxID=2056856 RepID=A0A2R7K4L4_9SPHI +---FRNKLNEIVKAHKATIGYSLLDLQNGDTV-TVNGAKHLPMQSVYKFHLALAVLHQVD +QGKLQLDQKILVRKQDLLPWSPLRDKYPAGNIPLSELLSFTVSQSDNNGCDILFRLMGGP +AKVQQYIRSLGVSEVAISATEEEMHRDDQMQFTNWSTARSATQLLAIFYAKPILSKSSAD +FLWKVMRETTTGPNKIKGLLPPATEVAHKTGNSGTAATNDIGIVTLPNGKHFAIAVFVSM +TTEDEKTTDRIIAELSKASWDE- +>[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax sp. SLBN-42 TaxID=2572897 RepID=A0A542J8Y4_9MICO +--RMAAALAELEHAASVTIGVVAVAHGSPNAF-RYRAADRFPMCSLFKPLAAAALVQARG +YDDAYWNTPIRYAEADVVSDSLVLDSKRPREATPGELADAALRRSDNTAGNLLLRELGGP +AAITAFAASLGATDTRLDRWEPELNEALPGDPRDTTTPDDIARLYTALLLDDAAGVLASS +RLREWMLRNRTSDARMRAGLTPPYELADKTGGGAYGVVNDAGVLWRAGEPPVTVVIMTRT +DRADAVRNNAVVADATRIVV--- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1A5 TaxID=2080523 RepID=UPI000CE87269 +---VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKVLAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEETTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSTR +NDPEA------------------ +>[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium linens TaxID=1703 RepID=UPI00111D431F +-qRLEEQLKDLEDRYDARVGVSAFDTESDESV-DYRADERFGFASSLKVFAVAELLDRTS +--PKEIEKNVSWTQADVDEWTPVTQKHVDDGLPLDDVAESALRVSDNLAMNIVLDELGGP +EALDDALEKSGDMTTEVTDEEPELNDVEDGSRDNTTTPAAFTNDLHRLLDPQQLSDDDRR +VLFDWMSANETGDPLIRAGAPEGWVVRDKSGHSD-AIQNDIAVVTPPDRHPIVISVMTET +DDPESEDGPALVSAVAEVVLDSf +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga rupis TaxID=573321 RepID=A0A1H7RIZ0_9BACT +--ALRQKMEAIIAGKQAHIGISMLAIEDKDTL-SINAAHHYPMQSVFKFHLALLVLHKAD +QGKLSLSQRIHIKQSSLAKWSPLRDEHTAPELTIKELLSYTVSQSDNNGCDILFGLVGGP +AALNNYIHALGVKDINIVANEAQMHAAWDVQYNNWTTPIAATQLLQKFQTGNILSENSKA +LLWQLMATGVK-SNRLKGLLPADTDVAHKSGTSDTAAFNDIGIITLPNGKHIAMAVFVSD +SKEDEATNQRIISEIAKAAWDHy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Mucilaginibacter sp. TaxID=1882438 RepID=A0A3C1BCF4_9SPHI +---LRRQIAQIAKPVKGIVGVSILSLEGRDTL-TYNGKARLVMHSVMKFPIALTVLHLVD +TGKLSLTQMVHIKKRDLEKYSALRDKYPKGDLSISELLNYMVSLSDNSACDILLKLIGGP +QHVQAYLLQLGIRGIAVRASEADMASAWELQFANWAKPYEMTLLLDQFYSGKVLTKSSTG +FLYKLMTETTTGPNRIKGLLPAGTVVAHKTGTSGTDATNDVGIITLPNGKHIAIAVFVCN +STNDEATREGVIANIAKAAYDFy +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium kwangjuense TaxID=267125 RepID=A0A135WIU6_9FLAO +-sSLEQKINSITTGKKATVGVSVLGFENNFKY-SKNGDKELPMLSVFKFHIGCAVLDLVD +KGKLSLDQKLFFKKEDMLEWSPIRDKYPDANLSLGEVLDYTVALSDNNGCDLLLKLIGGT +QTVQKFMDSKGVKGVQIKRNEDDMHKNWKTQYDNVSTPNSAVLVLKKFYDGKLLSKKSTD +YLMQIMLGTKTGTNKIVEQLPKSTPVAHKTGASGKGAENDIGIITLPNGKHYAIAVFVNN +STESDAVNCRMVSDISKAVWDDf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Spirosoma terrae TaxID=1968276 RepID=UPI0013CFA2BF +-rQLQQQIEQLATAAQGTVGVAATLVETGESV-SLHGDQPFPMQSVYKMPIGMATLHLVD +QGKLSLEQKIRVSTADYISHSPIREKYPNGTLSLAELLRYAVSESDGSASDVLMRVVGGP +NVIMSYLKSLGIKDLIVLNTEREIGSDNAVQYKNWAKPAEAVALLRRLQEGRGLSKSSRA +FLLRLMTETETGLHRLKGQLPVGTVVAHKTGTSWTAATNDIGLVTLPNGQHIAIAVFVSD +AKADTDTREAVIANISRAVWDYw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WHV5_9BACT +--QLKKDIVESINSIKADVGVAILHLENGDTL-SFNGLHHFPMQSVYKFHLALAVLHAVD +QGKLSLDHETFIAKSDFIPWSPIADKYPEGDLTVSQLLSYTISQSDNNGCDILFRLVGGP +RKVDEYIKGLGIIDVAIANTEAEMHENPDLQFKNWTTPRAMVQLLSLFYQGKILASPTHN +LLVEMMEQTITGNKRIKGQLPQGTVVAHRTGMSGRAALNDVGIITLPNGKHIAVALFVSN +TRESIPASEELIAKISRIVFDYy +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=A0A498CPX0_9GAMM +---VETEVARLATLVDGKVGVSAWRLDKGAQV-HLNPDEAFPMASTFKVAVAAVILTKVD +AGELALTTMVPVPKAFYVDSEVIADRFIHDGLSVHNLLEVMLTQSDNTATDVLVAQAGGP +AAVTAWLRAQGIEGQRLDRNTRQLLSAFDKDPRDTSTPRAMSTLLTRLFTGKALSPASTE +VLVQIMERCRTCSARLRGSLPPGTKVADKSGTVA-GTVNDVGVVTLPDGSQFAISVFVKA +SNAPRSERERVIAEIARTVRDFy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A649UHJ1_KLEPN +-----EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD +AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP +AGLTAFLRQIGDNVTRLDRWETELNQALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ +QLLQWMVDDRV------------------------------------------------- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Legionella sp. km772 TaxID=2498111 RepID=A0A3S0W2K0_9GAMM +---AHAGVKQIETKYNVKIGVYAIDTNNGNSF-SYRQDERFPFQSTVKMLVVAVALKNIE +-----ADERIKISSDDIVFWSPIVRLNLDRGMTIKELAEAAMRYSDNAATNILITRLGGT +KSINEFAKSIGDRSFNLENLEPNLNSD-PNNIHDSSTPKDMAESVQKLLENNVLGQENQN +ILKTWMMNNTTGYKKIRYGLPLGWSAAEKTGGGSV-ISNDIGIVWSPACKPIVLAIYTFS +NKKDAQKADKAIAETTKFILDEf +>[subseq from] Uncharacterized protein n=1 Tax=Legionella drancourtii LLAP12 TaxID=658187 RepID=G9EJ58_9GAMM +----DTKLQAIEHEHHLKIGIYALDTNSGRVI-TYHAHDRFPFQSTCKFIGVSALLASD- +--KTLLEKKVLINPKELLFWHPISGQYVNQKVPLKTLAEGAISYSDNTAINIIIRELGGL +GAINQFAQSIENSSFKMAHYEINLNSN-PQINEDTSTPKDMALSLKKIMLGDILTTPNKA +LLLDWMRNNTTGYNRIRAGVPLGWSVADKTGSGSYGIANDIGIVWSPVCKPVILSIFTVS +NQSDAKPSDAVIAQITKAAFEEf +>[subseq from] Class A beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6B2EWR4_KLEPN +------------------------------------------------------------ +---------------DLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter xanthus TaxID=1784712 RepID=A0A3A1P766_9SPHN +--AAASKLADIEQRSGGRLGVTLVDPEGQVLF-SHRGDERFAMCSTFKTLLAAKVLTGAD +--GLKLDDRLTIDPAAVEGHAPFTRSRLDAGMTVGEAAEHIVTVSDNAAANMLLDRVGGP +QGLTQWIRTLGDDVTRLDRRELELNENAAGDPRDTTAPLAFAETYRKVMNDEALGPAQRD +QLAGWLNASVTGLNRLRAGLPDGWRVGDKTGFCAAVEINDVAVFNPEGKGWYTLVFLLDR +PRETGAVVDALGAEVGALAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas TaxID=40323 RepID=UPI0008A5F171 +---VETEVARLATLIDGKVGVSAWRLDKGEQV-HLNPDEGFPMASTFKVAVAAVILTKVD +AGELALTTMVPVPKSFYVDSEVIADRFIHDGLSVHNLLEVMLTQSDNTATDVLVAQAGGP +AAVTAWLRAQGIEGQRLDRNTRQLLSAFDKDPRDTSTPRAMSTLLTRLFTGKALSPASTE +VLVQIMERCRTCSARLRGSLPPGTKVADKSGTVA-GTVNDVGVITLPDGSRFAISVFVKA +SNAPRSERERVIAEIARTVRDFy +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus lentus TaxID=42858 RepID=A0A178P2W8_STALE +----NSAIDKIEKKYDANVGMYALNTQNGEEL-SFNEDKRFAYASTLKAVSSAMLLEKVP +--SNKLDKKIHISKDDIVTYSPVLEKYVDKEITLKKLIEANMLYSDNTANNKVIDELGGY +KEVKKRLVDLGDTMTYPSRKEPDLNLYTPKDKRDTTTPLAFGKTLNKLIIDGNLSKSNKD +FLMNLMLKNKSGDTLIKDGAPSDFKVMDKSGQATYGSRNDVAFIYPKGQKPIILVIFTNK +NNKDAKPNDKIVSEVAEEVLK-- +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus lentus TaxID=42858 RepID=UPI0002D9E73F +----NSAIDKIEKKYDANVGMYALNTQNGEEL-SFNEDKRFAYASTLKAVSSAMLLEKVP +--SNKLDKKIHISKDDIVTYSPVLEKYVDKEITLKKLIEANMLYSDNTANNKVIDELGGY +KEVKKRLVDLGDTMTYPSRKEPDLNLYTPKDKRDTTTPLAFGKTLNKLIIDGNLSKSNKD +FLMNLMLKNKSGDTLIKDGAPSDFKVMDKSGQATYGSRNDVAFIYPKGQKPIILVIFTNK +NNKDAKPNDKIVSEVAEEVLK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Brevibacterium sp. MG-1 TaxID=2586910 RepID=A0A5C4X406_9MICO +--RLEEQLKDLEDRYDARVGVSAFDTESDESV-DYRADERFGFASSLKVFAVAELLDRTS +--PKEIEKNVSWTQADVDEWTPVTQKHVDDGLPLDDVAESALRVSDNLAMNIVLDELGGP +EALDDALEKSGDMTTEVTDEEPELNDVEDGSRDNTTTPAAFTTDLHSLLDPQQLSDDDRR +VLFDWMSGNETGDPLIRAGAPEGWVVRDKSGHSD-AIQNDIAVVTPPDRHPIVISVMTET +DDPESEDGPALVAAVAEVVLDSf +>[subseq from] Beta-lactamase n=1 Tax=Mucinivorans hirudinis TaxID=1433126 RepID=A0A060R6W8_9BACT +-nSLHSKINEIVKDKRATVGVAICPIGGTDTV-SVNGAAHLPMQSVFKFHIALAVLDQVD +KGALSLNQKIKLTMADLLPWSPIRDKYKCGDLSVAELIQYTVAQSDNNGCDILLRLIGAT +EAVEHYLQRIGVDDVAIKANEEQMQMVWDVQYQNCTTPLSAVRLLSKFYAGGAVSAKSRT +FLYDVMVNTTTGAKRLKGLLPAGTVVAHKTGSSGTAAVNDIGIVILPDGSAYAIAVLVSD +SAEDSTTNEAIIARVSQAAWQYy +>[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas bacteroides TaxID=74311 RepID=UPI0004959F88 +-------LSALEAREGGRLGFAAKDMGTGRML-AWRGEERFVYCSTFKMYLAAATLLRVQ +AGLERLDRMIPITRADMVNHAPVTEPAIGSSLSVEALMKGTVEVSDNPAANLLLQAMGGI +EPMQAFYRDLGDPTTRADRFEPEMNRL--DGEKDTVLPLQSVVNIQSLLIDTPLSADHKA +LLLKWMTDTPTGMARIKAGVPAGWTVAHKTGTGGYGPTNDIGVLYPPSGAPVIVAAYYHA +AC-DDPKNEGVIAEATRLAL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Mucilaginibacter sp. MJ1a TaxID=2599294 RepID=A0A563U1Y4_9SPHI +---LKNKINEIAKDAKGEIGVSMIDLQTGRSF-SINGDKPLVMQSTFKLPIAVAVLHKVD +KGSIKLEDKLRLTKADLPEYSPLRDKHPDGNVTIRELLDYMLIWSDNDACDILLNKVCSK +AEVEQYMHQLGGTSFWIRATEMEMKNDWQAQFTDVCTVTDMAKLFRTVRNGKALSAKSTE +YIIKTMEKTEVGKKRIKGLLAANTVVAHRTGTSATDATNDGGIITLPNGKQFILVVFVSN +AKADTNTREAVIARIAKVVYD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Novosphingobium sp. TaxID=1874826 RepID=A0A519QPB4_9SPHN +-----ATLKRIEQAARGRLGAFVLDPASGRSF-GWREHERFAHCSSFKLSLAAMLLGRAD +KGEVDLGEILHWSKADMLSTSPVTSLHIADGLPVGELARATLVTSDNTAANVLLRRFGGP +EAVTRFWRSTGDTVSRLDRYEPELNLTPPGAELDTTTPAAMAATLAKLVLGEVLAPGSRN +TLREWMIAVATGRNRIRAGFPVDWVSGDKTGTGIRHTYVDLAFGGPAGASPVIVTAYFEP +ERPMDPASTGALAEVGRLA---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1L6C4A0_ECOLX +--------------------------------------------------AVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPL-------- +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacteria TaxID=2 RepID=A0A0B5E494_9GAMM +-------------SVVARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEA---------------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium echinoideorum TaxID=1549648 RepID=UPI001186B213 +---LDQKINTIIKDKNATVGVAVLSIEDNFRY-NKNANKKLPMLSVFKFHIAAAVLDRVD +QGKLSLDQKIFITKKDLLEWSPIREKFPNGNMSLGEMIYYTVAWSDNNGCDILLRLIGGT +ETVQKLMDSKGVKNFRIKNNEEQMHKGIQYLYDNYTTPHSLAQLYKDFYLGKILSKKSTD +YLYNIMLNTETGTNKLKEQLPKK-TIAHKTGSSGKTAENDSGIVTLPNGKHYSIIVFISD +STEPEAVNCQMISDISKTVWDYf +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus caeli TaxID=2201815 RepID=A0A1D4NPI3_9STAP +--STNNDIEKLEKKYGANIGMYALNTQNGEEL-SFNENKRFAYASTLKAISSAMLLEQTP +--YNKLDKKIHINKDDIVPYSPVLEKYIGKEITIKKLIEATMLFSDNTANNKIIDELGGY +EHVKNRLTDLGDTTTHPSRKEPDLNFYSPKDKRDTTTPIAYGKTLNKLIVDGKLSKANKD +FLLDLMFKNKSGDTLIRDGASSNFKVMDKSGQATYGSRNDVALVYPDGQKPIILVIFTNK +DKKDGKPNDKIVSEVAKIVLK-- +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. BN140078 TaxID=2607653 RepID=A0A5B2VJB2_9BACT +-qSLNARLQQIAATIKGKVGVSALLLETGQTA-ELNAQQHYPMQSVYKFPIALAILQQVD +KGKLQLNQPVQIAKAELIPHSPIRDNHPDGVMPLREVLRYNVTESDGTACDVLLRLLGGT +KATQKAIEALGIKDIAIATTEMVQVSDELVQYRNWSTPIAMTRLLRIFYTKEVLSPASKA +LLLKDMTETPVGPQRLKGLLPKGITVAHKTGTSGTRATNDAGIITLPDGRHLIITVYVSD +AHGTTAEKEGIIAKMAKACYDEw +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=bacterium HR33 TaxID=2035428 RepID=A0A2H6A5S6_9BACT +-qRLERELARIAALTDGKVGLAALHLETGRAA-YLNPDEPFPMASTYKVPIAVELLTRVE +RGEVGLDTLIELRPQDLHPGSGTLTELFDDPLSLRNLLELMLLISDNSATDIVLRVAGGP +QAVTERMRRLGIDGIRVDRPTIQLIARFDQDPRDTATPRAMTSLLAKIWRGEALGDSATA +LLLDIMRRSTTGAGRIKGMLHPDVIVSHKTGTIG-GTTNDVGIITLPDGGHVALSVFIKG +STLTVEQRERVIAHLARAVYDYf +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. LM091 TaxID=1904944 RepID=A0A1D8YE86_9GAMM +---VETEVARLATLIDGKVGVSAWRLDKGEQV-HLNPDEGFPMASTFKVAVAAVILTKVD +AGELALTTMVPVPKSFYVDSEVIADRFIHDGLSVHNLLEVMLTQSDNTATDVLVAQAGGP +AAVTAWLRAQGIEGQRLDRNTRQLLSAFDKDPRDTSTPRAMSTLLTRLFTGKALSPASTE +VLVQIMERCRTCSARLRGSLPPGTKVADKSGTVA-GTVNDVGVVTLPDGSQFAISVFVKA +SNAPRSERERVIAEIARTVRDFy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Amniculibacterium aquaticum TaxID=2479858 RepID=UPI000F5A1475 +--DLQNKINQITSDKKALIGVSILNLDGREVA-SINGQEKLPMQSVYKFHIALAVLSEVD +RGRFSLDQKVDIKKSDWYPWSPMRDDNPEGGFTVAQLLEYAVSKSDNIACDELLKLLGSP +KNVDAYIKSQGIKNVSIKLTEKEMQATWDAMYENWTTPHAASEIAYKFYTKKLLSQKSHD +FLWKIMHETNTGENRLKGNLPNGTIVAHKTGTSGRKACNDMGIVMLPNGNYFVITVFVTQ +SKENDAENEKIIAEISKAAYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007D6D126 +------------------------------------------------------------ +----QLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMGDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus lentus TaxID=42858 RepID=UPI0007D8EC96 +----NSAIDKIEKKYDANVGMYALNTQNGEEL-SFNEDKRFSYASTLKAVSSAMLLEKVP +--SNKLDKKIHISKDDIVTYSPVLEKYVDKEITLKKLIEANMLYSDNTANNKVIDELGGY +KEVKKRLVDLGDTMTYPSRKEPDLNLYTPKDKRDTTTPSAFGKTLNKLIIDGNLSKSNKD +FLMNLMLKNKSGDTLIKDGAPSDFKVMDKSGQATYGSRNDVAFIYPKGQKPIILVIFTNK +NNKDAKPNDKIVSEVAEEVLK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1L6C498_ECOLX +-----------------------------------------------------AVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLIWV----- +----------------------- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Spirosoma sp. BT328 TaxID=2692134 RepID=UPI00141003A4 +--QLQTNIEQIIKNKKATVGVSIYESGSRQTL-IINGDKHMPMQSVYKFHLALAVLNEVD +KGRLKLSQKMHVRKSDIIPHSPMGEVYPNGELPLSDIIRYMVADSDGSACDYLFRLLGGP +KQVDAFIHQLGIRDVAIRDTEEMMQANWDVQYTNWTTPSAMLRLLKLFYQGKILSASSHD +FLWKVMVGTTTGQDRLKKLLTAGTVVAHKTGTSGTGAVNDVGYIVLPNGKYLIISVFVTN +STETIQTNEQIIADIAKSAYNHf +>[subseq from] Beta-lactamase (Fragment) n=8 Tax=Enterobacteriaceae TaxID=543 RepID=G3LSZ6_ECOLX +-----------------------------------------AMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNHIA------------------ +----------------------- +>[subseq from] Class A beta-lactamase n=2 Tax=Spirosoma montaniterrae TaxID=1178516 RepID=A0A1P9X4C7_9BACT +-dALRQKLQQIISTKNAVVGVSIIANNGKDTL-SLHGNRHCPTQSVFKFHAALAVLDQID +KGKFSLDQKVAVQKKDLLPWSPLREENPDGGFAISKLIQYAVSQSDNVACDALLRLLGGP +QVVEGYIRENGIKDISLKFNEEDMQAQWDNMFQNWTTPIAASETLRKFYDNQLLSPKSYA +FIWRIMKETTTGEGRLKGLLPKGTIVAHKTGSSGTNATNDIGIVFLPNGNYFIISVFVAN +STENDQTNERIIAEIAKATWDHy +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. SAORIC-644 TaxID=1869314 RepID=A0A2K1DY47_9SPHN +-qDLAARISEIEKASGGRLGLALHSPDKGLVY-AYRGDERFAMCSTFKLALAAMTLDTPG +----LREKRLHFGAGDILSYAPYAKERASFGMSGLEAAHHAVTLSDNTAANLLLAEVGGP +DGFTRWLRSMGDETTRLDRNEPALNENAPGDPRDTTTPTAHADLVGTLLWGDRLAQADRA +LLQEWLVETTTGMNRLRAGLPGEWRAGDKTGTCGQGEVNDIAMFETSDGSRYILAAYLDR +ADGSASDAEARLAEAARAIAD-- +>[subseq from] Beta-lactamase n=4 Tax=Escherichia coli TaxID=562 RepID=Q9X6W1_ECOLX +-dSLKSSIEKYLKDKKAKVGVAVLGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKLD +KENISIDKKLFVKKSELLPWSPLRDKYPDGNLSISEILKATVSRSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD +YLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] Uncharacterized protein n=1 Tax=Dyadobacter sp. 50-39 TaxID=1895756 RepID=A0A1Q3PLZ9_9BACT +-aKLKSEIETISKQAKGIVGVGVMDLKTKGTL-LINQDHKFPMQSTFKFPLAIAVLDLVD +KGKYKLDQKIHVTREELDQHSPMRDKLPNRDITLGELISYSVSESDNNACDILFRLAGGT +RKVNDYIHSLGVKDIAIVATEREMKAGWEVQYTNYARPSAYLQLLQIAFERNKLSKASHD +FLWKVLVEGPTGLKRIKGLLPKGTEVAHKTGTSNTAATNDAGIMKLPNGKAIAVVVFVSD +AAADMDTRERVIAQVAKAAWDYy +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Microvirga TaxID=2617746 RepID=UPI001378F8B1 +--TLAARIEALDRETSGRLGVGLVDLKDGSAW-SWRGDERFPMQSVYKLPIALAILTAVD +EGRLNLDDTIALGREDLSIWSPIAREFKGERYTVRQLAEHALQLSDNTASDTLLRLAGGP +GSVTALLYRHGIAGMRVDRSEREMQPAYLADVRDTTTPKAAAHLLAKLARGELLSEPMTR +IFLGILAGTRTGGSRIKAGVPEGSAVAHKTGTAMTGAVNDVGIVTLPSGRQIVVAVFVAG +SDRPPAERERLIASVTRAAIE-- +>[subseq from] Beta-lactamase n=2 Tax=Acidisarcina polymorpha TaxID=2211140 RepID=A0A2Z5FTD0_9BACT +------------------------DGQSGLAF-GHRINDLFPMCSTFKVLAVAAALAQVD +SKRLDLRQTLSINPEDLLKYAPVTSQHLGLPMTLGDLCEAALTLSDNTAANLILRSIGGP +VQVTRFARLLDDSITRLDRAEPTLNEATPGDRRDTTTPLAMAKDLRKLFCGSVLSGASRS +LLKEWMIACKTGDKKIRSGFSKSFVIADKTGSGDHNTSNDVAVIWPANQSPLILTV---- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Stenotrophomonas humi TaxID=405444 RepID=A0A0R0C0C2_9GAMM +--GLQAEAQRLSALLPGQLGAAIVHLESGRSV-FLNADHPFPMASTMKVPVAVHILTLVD +EGKLSLQQQVTLGPDDVYPMGGPMDLHLSAGITVRDLLHMMITVSDNNATDILIRLGGGT +HAVNARMQALGISGMRVDRYIWELLAAWNEDPRDTSSARAMATLLQKVWRGEVLKPTSTQ +LLQEIMRDTRTGAARLRGMLPKDTPVAHKTGTVGD-VINDVGVITLPGGRGHAIVTVFVQ +SRASSEERDAAIAQLARAAHDYf +>[subseq from] Uncharacterized protein n=1 Tax=Rodentibacter trehalosifermentans TaxID=1908263 RepID=A0A1V3IXX0_9PAST +--DWQQAITQQEQKLKANIGVALLAADGKVLF-EYQGHRPFPLNSTHKAFICGIALDLAD +NNGLSFTQKLPILPKEIVNYSPITQHK--TEMNLTALCSAAVSYSDNTAANLIVKQIGGI +KAVTDYFKRQGLNQTRLDRPEPDMNRDNLKKGLDLTTPIEAAQLLQQFTFGNLLSNSSKR +LFIQWMFDDQVANDLLRSTLPQGWKIADKTGAGSNGARSIISVFWKPDGTAYLLSVYLTN +TQATMAQRNQAIAEIGKTIFDH- +>[subseq from] Class A beta-lactamase n=1 Tax=Rathayibacter caricis DSM 15933 TaxID=1328867 RepID=A0A2T4UYR7_9MICO +--AVETALAALEAEYDARIGLVAVDTEDERTV-EHRADEQFRFASAIKALAAGALLARTE +--PADLERVVTW--SDVVDHSPVTGPATATGLPLGEVAEAAVRLSDNTAHNVVLQELGGP +AGLQEALRALGDDVTRIDRIEPELNRVSPE-GLDTGTARSLAADLRALLLGDALHPVDRA +QLRDWMSGNATGDALVRAGAPDGWSVLDKSGGAG-GLRNDLAVVERPDAAPIVIAVLTER +SDPSLPYDDALVARAASVALE-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. PAMC 26605 TaxID=1112214 RepID=UPI00026CA664 +-----AALAALEQRHGGRLGVYALDLATGRAL-SHRAGERFKLMSSFKGLLSALMLYEVA +HGRDTLDAAVSFGASDLMDASPVTEANVTRGMTVRELCAAIMYRSDNAAANLLMRRVGGP +ARVTAFLRAIGDRVTRVDAYEGHLLDR--PLPADSSTPRAVTETMRRLMLGSVLSAADRR +QWEGWMAGNVVGRSRLRAAFPRAWTAGDRTGTAD-GICNDFAFARRPGTAPLLISAYYTA +PGLDMPAQEAVLRAVARRVV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Citrobacter freundii TaxID=546 RepID=A0A509IQL3_CITFR +------------------------------------------------------------ +-------NASIILKNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWGPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVTGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Providencia sp. wls1919 TaxID=2675154 RepID=UPI0012B57A5D +--TLQEQVKQYEKE-GWKVGLSIL-FSNDKAI-SINGEQRFPLDSTVKSIACANALAKVD +AKKLSLSHSMIVTEENIVTYSPVAKDYMNKSFTLEQACKAANEYSDNTAANFAIFSGGGP +EALTAFMRAIGDTVTRSDRYEPELTVNPEGDLRDTTTPDAMSKSIKKILTGEVLSNSSKE +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASEYGVRGITSMVWSDNHEPVFISIYVRK +ADTSLDERSEVIRVLGSHIFDEy +>[subseq from] Beta-lactamase class A n=1 Tax=Brevibacterium iodinum ATCC 49514 TaxID=1255616 RepID=A0A2H1HPT7_9MICO +hqEVEDQLKDLEDRYDARVGVSAVDTGSDESV-DHRADERFGFASSLKVFAVAELLDRTT +--PKELEKNVTWTQADVDEWTPVTEKHVADGLPLEDVAESALRVSDNLAMNIVLDELGGS +KALDDALDRAGDTTTEVTDEEPELNDVEEGDTDNTTTPAAFTTDLLGLLDPQRLSDDDRK +VLFDWMSANETGDPLIRAGAPEGWVVRDKSGHSG-AIQNDIAVVTPHDREPTVISVMTET +DDPKSEDGPALVAAVAEVVLNEf +>[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas humi TaxID=405444 RepID=UPI00070D4F4B +--GLQAEAQRLSALLPGQLGAAIVHLESGRSV-FLNADHPFPMASTMKVPVAVHILTLVD +EGKLSLQQQVTLGPDDVYPMGGPMDLHLSAGITVRDLLHMMITVSDNNATDILIRLGGGT +HAVNARMQALGISGMRVDRYIWELLAAWNEDPRDTSSARAMATLLQKVWRGEVLKPTSTQ +LLQEIMRDTRTGAARLRGMLPKDTPVAHKTGTVGD-VINDVGVITLPGGRGHAIVTVFVQ +SRASSEERDAAIAQLARAAHDYf +>[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus lentus TaxID=42858 RepID=UPI0011CB8B96 +----NSAIDKIEKKYDANVGMYALNTQNGEEL-SFNEDKRFAYASTLKAVSSAMLLEKVP +--SNKLDKKIHISKDDIVTYSPVLEKYVDKEITLKKLIEANMLYSDNTANNKVFDELGGY +KEVKKRLVDLGDTMTYPSRKEPDLNLYTPKDKRDTTTPLAFGKTLNKLIIDGNLSKSNKD +FLMNLMLKNKSGDTLIKDGAPSDFKVMDKSGQATYGSRNDVAFIYPKGQKPIILVIFTNK +NNKDAKPNDKIVSEVAEEVLK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=A0A3D8Z8S0_STAPS +----------------AHIGVYALDTKSGKEV-KFNSDKRFAYASNSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SD48_9BACT +--------------------------------------QRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSPH +TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Arcicella aurantiaca TaxID=591202 RepID=A0A316EG94_9BACT +--ILREKIATIIKSKNAKIGVSVLNLSNGDTL-TFNKTHHFPMQSVYKFHLALAILNQVD +KKKFSLNQPIFVSKADLRPWSPLRDKYPEGNIPLSEIIAYTVSQSDNNGCDRLFRLMGGA +IKANEYIHKIGVKDVNIVATEEEMQKDWQVQYTNWSTPAAATKLLQKFYQQGIMSKNSQD +FLWKVMVETTTGPNKIRGLLPKDATVAHKTGFSGTGATNDIGIVILPNGKALAIALFVSN +STETELTNDRIMADITKVVWDYy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Variovorax sp. s4p23 TaxID=1367569 RepID=A0A0B5E4A1_9BURK +--------------ADNRVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEA---------------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma oryzae TaxID=1469603 RepID=A0A2T0RWT4_9BACT +-qSLQEKIERVINGKKATVGVGIYDFGSRQTL-TINGDEHMPMQSVYKFHVALAILHEVD +KGRFKLTQKMRVKKSDLTPHSPMGEDYPNGVLPLSELIRYMVAESDGSACDYLFRLLGGP +KQVDTFIHGLGIRDVAIRETEAVMQANWDIQYANWTTPKAMLSLLTRFYQRNVLSPSSHD +FLWKTMVSTTTGENRLKKLLPAGTVVAHKTGTSAMGAVNDAGFIILPTGKCIAISVFVTN +STEGIATNEQIIADIARLAYDHf +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1E1 TaxID=2080549 RepID=UPI000CE8E475 +---VSAELAVLENEFDARNGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP +--AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDSTALNLVLRRLGGP +SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLVAVATGDVLSSEDRA +LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR +NDPEADYDDALVARAAAVVL--- +>[subseq from] Uncharacterized protein n=1 Tax=Rodentibacter heidelbergensis TaxID=1908258 RepID=A0A1V3I7A2_9PAST +--DWQQAIHQQEQKLKADVGVALLS-EEGKILfEYQGHHHFPLNSTHKAFVCGMALDLSE +DNRLSFQEKLPIHATEIVSYSPITEHK--SSMNLTELCSAAVSYSDNTAANLIIKQLGGV +SAVTDYFKQVGLTQTRLDRTEPDMNYDNLKKGLDLTTPIEATQLLHQFIFGDRLNDNSKM +QLIQWMLDDQVANDLLRSTLPKGWKIADKTGAGTAGSRSIISVFWKPNGRAYLLSIYLTN +TQATMAERNQAIAEIGRVIFN-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium carnipullorum TaxID=1124835 RepID=A0A1M7L010_9FLAO +-sALEQKINAITEGKKATVGVSVLGFENNFKY-HKNGDKPLPTLSVFKFHIACAVLDLVD +KGKLSLDQNIFFKKEDMLPWSPIGKKYPEGNIPLEEVLDYTVAQSDNNGCDMLLKIIGGT +KTVQNFMDSKGVKGFQIKRNEDDMHKNWKTQYDNYSTPNSAVLVLKKFYDGKLLSKKSTD +YLMKIMIGTTTGTNKIVEQLPKNTPVAHKTGSSGNGAENDMGIITLPNGKHYAIAIFVSN +STETDAVNCKVVSDISKAVWDDf +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium gambrini TaxID=373672 RepID=A0A1N7Q618_9FLAO +-sSLETQINSIIKNKKATVGISVLGFENGFTY-NKNADKKLPMQSVFKFHIAAAVLDYVE +KGKLSLDQKVSLNQSNLHEWSPLREKYPNGGVPLSEIIEYTVAKSDNNGCDILLKLLGGT +QVVQKFMNAKGVKNFQIKYNEEAMHKDWNAQYENYTTMNSAVDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGTNKLIEQLPKDTPIARKTGSSGTGAENEIAIITLPNGKHYAIAVFVSN +STETAEVNCRMISDISKTVWDYf +>[subseq from] Beta-lactamase n=1 Tax=Gordonia effusa NBRC 100432 TaxID=1077974 RepID=H0R324_9ACTN +--AIEAQIRDAAAMSGAEIGVAAYDPATGATV-KVNSANRFPMLSTFKTYAVAEILRKHG +-IGARLDARVRITSADIVVNSPVTSAAVGTSMSLQELCIAALTRSDNTAGNLLLRDLGGP +TSIATTARRLGDDQSSLTRIEPDLNSAAPGDFRDTTTPDGLLSGYRQLLDGGAG-QHIST +QLLEWMRATKTSDQRTRAGLPAGWTTADKTGSGDYGTTNAAGVILTPSGKRLYLVIMTRD +ARSDAPAFNALLARVTQLL---- +>[subseq from] Class A beta-lactamase n=1 Tax=Agromyces sp. KACC 19306 TaxID=2592652 RepID=A0A5C1YAA7_9MICO +------ALRRLERETSVTIGVTAVVHGTERVF-RYRGGDRFPMCSLFKVLAAGALVRARG +YDDGYWTRAIPYTDADIVRDSIVLATKQPQQATPGELADAALRFSDNTAGNLLMRELGGP +AAITAFAAELGATATRLDRWEPDLNAAIPGDLRDTSTPDDIARMYEALLLDDAAGVLASS +RLREWMLRNATSGTRMRAGLTPPYELADKTGGGDYGVVNDAGVLWRPGRTPLTLAIMTRA +DRADAVRNDDVVARATRIVL--- +>[subseq from] Serine hydrolase n=1 Tax=Chamaesiphon polymorphus CCALA 037 TaxID=2107692 RepID=A0A2T1GN43_9CYAN +-------------AAQGRVGVGVMDLNTGKSW-FYNGERRLPMQSVYKLPVGIVVLKQVD +AGKLSLDRPVTVSRQDFAPWSPIRQEITGDSYTVRELLERAVGVSDNTAVDVLIRLVGGP +ERVTATLRQMNIRGIRVDRLERQLQPRYLSDPRDTATPKETIDLLAKLQSRQLLSENSTA +LLLKIMTDSPTGQQRLKAGLPQGWSIAHKTGTGPGTATNDVGIITSHGK-QVAIAVFVAG +SKAPIAKREQIIAQVATTVVQ-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. s1p23 TaxID=1367552 RepID=A0A0B5E3B3_9PSED +----------------ARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEA---------------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DAA75E4 +------------------MGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8PC51_9BACT +-kKLRNEIEQITLAAKGRVGVAEVVLETGETV-SLNPHDHFPMQSVYKLPIGMAVMKQVD +AGKVRLDQKVRVTKDDFIGHSPIRDKYPNGTLTVNELMGWMLLESDGTASDVLMKLIGGP +ETIQAFLTELGIKDMIVLDTEKAFGQDHSLQFRNWATPEAAVVLLRALHERRGLSESSQG +LLLKYMTESRPGAKRLKGLLPAGTIVAHKTGTSGTAATNDIGIITLPNGRHLAIAVFVAD +SAADEATREGVIAKIAKAVWDKw +>[subseq from] Class A beta-lactamase n=1 Tax=Neokomagataea tanensis TaxID=661191 RepID=A0A4Y6VAA1_9PROT +--TFTEQLHQLEHNSGGKLGVCALDTRSGRQF-GWRMEERFCHCSTFKLSLAALTLRESD +AGRLNLQETLPIERKDIVAYSPIVEKNLDKGLSIFSLAEAIQTTSDNAAANILLSKLGGP +EAVTRFWRDIGDNTSRLDGYEPTINVIPPGTVLNSTTPKAMAATVQKIVLGNVLKPESRS +HLLTWMNSTTSGLKRIRASLPQGWTGYDKTGSGMGNKTNDLALLVPPDNSPLIVSAYFEN +PENIRQSDEDILKKVGEI----- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophaga parva TaxID=2169414 RepID=A0A2T7BEV4_9BACT +-tSLHQQFQDIAAQAKGRVAVYAQVLETGDTA-SLNAHVHAPMQSVYKFPIAMAVLHTVD +QGKLKLDQPVHVTKADYIRHSPLRDAHPDGNVTVRELLRYNVAESDGSACDVLLHLLGGT +AAADKYIHSLGVKEISIATTEKVQTENERIQYRNWSTAAGLVQLLHIFYTGRKLSPSSQQ +LLMDLMVNSTPGAHRIKGQLPAGTVVAHKTGTSGTRATNDTGIITLPNGQHVLLAVLVTD +SRADEATREQVIAATAKAAFDHw +>[subseq from] Class A beta-lactamase n=2 Tax=Pedobacter cryoconitis TaxID=188932 RepID=A0A127V8V0_9SPHI +-nDLRKRLQHIVSSHAATIGFSLIDLQNGDTI-TVNGAKHLPMQSVYKFHLALAILNQVD +KGKLRLDQKILVKKADLLPWSPLREKYPNGEIPLSEILSYTVSQSDNNGCDLLFRLMGGP +AKVNQYIHSLGIKQVAIVATEEQMHKDENVQFTNWTTPVAATDLLKLFYSQKILSKTSHD +FLWKVMTETVTGANKLKGLLPAGTLVAHKTGNSGTTATNDIGIVTLPNGKHFAVAVFVSM +TKEDEKASDLSIAELTKASWDY- +>[subseq from] Beta-lactamase n=1 Tax=Flavipsychrobacter stenotrophus TaxID=2077091 RepID=A0A2S7SS00_9BACT +htTLRQQLATIGNVHSGSIGISVRAIEDQDTL-TVNNSHHYPMQSTFKFPLALYVLHKVD +KGQLALDQKIHISKEELYRWSPLREKYPDGNITIAELLDYTVSKSDNNTCDILFKLVKGT +YPTNKYIHKLGVKDIDIVATELQMGKGWGVQYTNWTTPSAMTDLLYQLYTGKCLSPGSTQ +FLMKLMTESANSDKRIKGLLPAGTIVAHKTGTSNTAAVNDLGIITLPNGKHLAIAVYVSD +TKEKSTEAEHVIAEIAKAVYDEy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Spirosoma sp. I-24 TaxID=2666025 RepID=UPI00138E8F61 +--QLQTKIEQVIKSKKAIVGVGLYEFGSQQTI-TINGDKHMPMQSVYKFHVALAVLREVD +KGRLKLNQKMHVKKSDLVPHSPMGEAYPNGELPLADIIRYMVADSDGSACDYLFRLLGGP +RQVEAFIHQLGIQDVAIRNTEEMMQANWNVQYTNWTTPTAMLSLLKLVYKRKILSASSHD +FLWKVMVGTTTGENRLKKLLPAGTVVAHKTGTSGMGAVNDAGFIALPNGKYMAISVFVMN +STERIEMNERIIAEIAKVAYDHf +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium elymi TaxID=395936 RepID=A0A3D9DPS7_9FLAO +---LEQKINSIIKDKKATVGVSVIGFENNFKY-NKNGDKPLPTLSVFKFHIACAVLDLVD +KGKLSLDQKLFFKKEDMLEWSPIREKYPDANLTLGEVLDYTVALSDNNGCDLLLKLIGGT +QTVQKFMDSKGVKGFQIKRNEDDMHKNWKTMYENYSTTNSAVQVLKKFYDGTLLSKKSTD +YLMQIMLGTKTGTNKIIEQLPKGTPVAHKTGSSGKNAENDMGIITLPNGKRYAIAIFVSN +STETELVNCKIVSDISKAVWDDf +>[subseq from] Uncharacterized protein n=1 Tax=Stenotrophomonas acidaminiphila TaxID=128780 RepID=A0A0R0DM61_9GAMM +--ALQAEAERLAAQLPGDVGAALVHLESGRAV-YLNADQPLPMASTMKVPVAVHILKLVD +EGKLGLQQQVLLGPEDIYPGGPM-DTHLSAGITIRDLLHMMITVSDNNATDILVRTGGGP +EAVQQRMRALGVDGLRVDRYIWELLAAWNADPRDTSSARAMAQLLQRTWKGEILSPASTA +VLQQIMLDTRTGSARLRGMLPSGTPVAHKTGTVGD-VINDVGVIELPNGRGHVVAAVFIR +SRASSEARDAAIAQLARAAHDYy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Candidatus Magnetomorum sp. HK-1 TaxID=1509431 RepID=A0A0M9E142_9DELT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLI--------------------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=bacterium 336/3 TaxID=1664068 RepID=A0A0M9DP66_9BACT +-qNIRQKIDSLLKTKKADVGIAIYDLQSKDTI-TWGNYRKYPMQSVYKFHLALAVLHQVD +KGKLSLEQKILVKKSDLLPWSPLREKYPQGNLPLSEIIHYTVAISDNNGCDILFRLLGGT +KKVHKYIKSLGIKEIAIKATEEEMHKEWDVQFTNWTTPLATVQLLEIFHQKNILSKTSQE +FLWKTMVETSTGLKRMKYLLPKNTIIAHKTGTSDNKAINDMGIIMLPNGNYIAVCVFVSN +SKEDFQTNEQIIADVTKMIWDE- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterococcus faecalis TaxID=1351 RepID=Q47757_ENTFL +----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPND-------------- +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter endophyticus TaxID=1808508 RepID=UPI00135D4A49 +--EALAAIARVEQESGGRLGVALRANGGDLKL-SYRGDERFALCSTFKVLLAARVLQLRE +-SHALENRNLTYDESDIAGWAPYAKEHLAEGMSVEAAAEYAVKQSDNTAANLLLDATGGP +SSLTRWFGRNGDSETRLDRNEPELNSNDAGDPRDTTTPEAISESFRRALFGNILDAEYRG +TLLGWMAESPFGTARLRAGMPQAWPKGSKTGTCAQGEVNDVAWFQTPDGEEYILAAYLDR +PAGDKADAERALAKVGRIAAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingorhabdus sp. Alg231-15 TaxID=1922222 RepID=UPI000D553974 +------QLAAIEQRIGGRLGVALMD-GNGSLImMHRGSERFAMCSTFKAPLASVLFAAHE +AGTVDMFEEFNLKPSDGVPYMPFVEKKLSEKVSLHELAGAAVMTSDNAAANLILKATGGP +EAFTKFVRANGDKITRLDRIEPELNENAPGDPRDTTSPEAMAGLMQKLLIEGAPLDIDKL +TLQKWMKESKTGASRIRAGLPKGWPVGNKTGTAPGGASNDMAIIWPSTAKPVILTVYTDR +PTASAQAVEAAMADVARVVI--- +>[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=3 Tax=Staphylococcaceae TaxID=90964 RepID=UPI00066D6752 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKS------------------- +>[subseq from] Serine hydrolase n=1 Tax=Shinella sp. TaxID=1870904 RepID=A0A2W6SZR1_9RHIZ +---LQVEAQRLAAQLPGQLGAAIVHLESGRSV-YLDADRAFPMASTMKVPVAVHILKLVD +EGKLTLQQQVTLDEDDVYPMGGPMDLHLSAGITVRDLLHMMITVSDNNATDILIRLGGGT +TAVNARMQALGISGMRVDRYIWELLAAWNEDPRDTSTARAMATLLQKVWRGEVLQPGSTK +LLQDIMLDTRTGSARLRGMLPKETPVAHKTGTVGD-VINDVGVITLPGGRGHAIVTVFVQ +SRASSEDRDAAIAQLARAAHDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium shigense TaxID=297244 RepID=A0A1N7HYF0_9FLAO +-sALEQKINAITEGKKATVGVSVLGFENNFKY-HKNGDKPLPTLSVFKFHIACAVLDLVD +KGKLSLDQNIFFKKEDMLPWSPIGKKYPEGNIPLGEVLDYTVAQSDNNGCDMLLKLIGGT +QTVQNFMDSKGVKGFQIKRNEDDMHKNWKTQYDNYSTPNSAVLVLKKFYDGKLISKKSTE +YLMKIMIGTTTGTNKIVEQLPKNTPVAHKTGSSGNGAENDMGIITLPNGKHYAIAVFVSN +STETDAVNCKVVSDISKAVWDDf +>[subseq from] Beta-lactamase n=1 Tax=Microbacterium foliorum TaxID=104336 RepID=A0A4Y5YR97_9MICO +---VEKELVGLEQEYEASIGVVALDTATGESV-SYGGDRRFGFASTVKVFAAAEFLRSVH +--GPDRDELVRWTAEEAASHAPVTSQYVEGGLTYAQLAEAAVRFSDNAALNLILDRIGGP +AALDGALESLGDATTEVANDEPTLNTIEPGSTEDTTTAAAFTASLATILDGAALSTADKT +LLIDWMSDNRTGDALIRAGAPDGWTVADKSGGAG-AIRNDIALVTPPERDPIIITVLTSR +NDPEAAFDDTLVARAASVVLN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Holophagales bacterium TaxID=2478486 RepID=A0A6B0XK47_9BACT +--HLGAEIERLAEASLGTVGVAAIHLESGRGV-LLNADDQFPMASTYKVPIAVEILAQVD +EGKRSLDDLITMQTSDHVATYGVLSDFFDTPLTIQNVLGLMLRISDNIATDLLFREAGGA +EAITGRMKAFGAEGIRVDRTTRALIATFNADPRDTATPRSMAALLRKIWKREILSEKSSA +LLIDIMARCQTGENRIPGALPPGTPVAHKTGTIGE-STNDVGVITLPGDGHVISVVFVKE +SRPSNAAMEPVIAEIARASYDYf +>[subseq from] Class A beta-lactamase n=1 Tax=Holophagales bacterium TaxID=2478486 RepID=A0A6B0W3C0_9BACT +--HLGSEIERLAEASLGTVGVAAIHLESGRGV-LLNADERFPMASTYKVPIAVEILAQVD +EGKRSLDDLITMQTSDHVVTHGALSDFFDTPLTIQNVLGLMLRISDNIATDLLFREAGGA +EAITVRMKAFGAEGIRVDRTTRALIANWLGRD-DAT------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. OV715 TaxID=1500287 RepID=UPI0006473BD3 +---LEQKINSITEGKNATVGVSVLGFENNFKY-SKKGDHPLPTLSVFKFHIACAVLDLVD +QGKLSLDQKLFFKKEDMLEWSPIREKYPDANLPLSEVLDYTVALSDNNGCDVLLRLIGGP +QTVQKFMDSKGVKSFQIKHNEAEMHKSWKALYENYSTPNSAVQVLKKFYDGKLLSKKSTD +YLMQIMLGTKTGTNKIVEQLPKNTPVAHKTGSSGKNAENDMGIITLPNGKHYAIAVFVND +SMETDDVNCKMVSDISKAVWDDf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Mucilaginibacter sp. L196 TaxID=1641870 RepID=UPI00131E7018 +---LRPQIAEIAKSAKGIVGVSVLGLEDRDTV-NYNGNARLVMESVMKFPIAMAVLHLVD +SGVLTLNQTIHIKKKDLPPYSPLRDKYPNGDVSINDLMSYMVSQSDDDACDILLEKLGGA +DQVEYYLHMIKVRGINIEASEEDMAKTPESQYTDWCKPKAIIQLLDTLYTGNVLKPASRD +YLNKLMVATTTGPNRIKGLLPAGTIVAHKTGTSGTNGTNDVGVITLPNGKHVAIAIFITN +STADEATRDLVIAKIAKAVYDN- +>[subseq from] Beta-lactamase n=2 Tax=Sphingopyxis TaxID=165697 RepID=A0A0Q8RLM9_9SPHN +---LARAVTAIEQRSGGRLGVAVTDARGALLF-GHRADERFAMCSTFKLLLAGQVLAKAA +-HGVSLRTPLRFVRADLVAYSPGTDKLLGPNQQLGFAAKDAVVLSDNSAANLILAHIGGP +AAFTAEIHRRGDQVTRLDRNEPTLNENAPGDVRDTTSPAAMVKSAAGYIYGDWLTAGHRD +TLRGWLIESETGLGRIRGGLPQGWLAGDKTGTCGT-AYNDVAFAEEPGGAKYMIAVYLDR +PAVKGDDANAVIADVARAVVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter sp. HI0020 TaxID=1822223 RepID=UPI0012E769F8 +---LVDDLQDIERRFNGRLGAHIIDTENGANV-GWRENERFAHASSFKMSLAAMLLARSE +RWEVDLEERLHWSEEDILFVSPVTKANTATGLTVRELAAATQITSDNTAANVLLKRFGGP +SEVTRFWRSIGDDVSRLDRYEPELNDVPPGTSSDTTSPSAMARTVKRLIVGGALSLENRA +LLSRWMIATETGLERLRAGFPSDWIAGDKTGTAVVHTYVDLAFGGPEGHAPLIVAAYFEP +NEPQEPMDANALAAVGRI----- +>[subseq from] class A beta-lactamase n=1 Tax=Steroidobacter sp. JW-3 TaxID=2497877 RepID=UPI0013007C74 +--TLEAEIARVSQPIGGKVGVAAWKLDKGGQV-LVNAGDRYPMASTFKIAVAGAILAQVD +AGKLKLDQLVPVQPNDIVPSDGIATLHPGISLSVHNLLELMLTLSDNTATDVLTRLAGGP +QAATAWVRKQGIEDQRIDRDTAALLRAFDKDVRDTSTPTAMAQLLTRIFNQQTLSASSTK +VLIEIMQRCHTGAGRLLGRMPAGTVIAHKTGTIG-GTVNDVGVITLPDGGQVVIAVFIKE +SDKSMEEREKVIAEIARSVRDFy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chitinophaga pinensis TaxID=79329 RepID=A0A5C6LWQ7_9BACT +------------ATARGHVGVAMMSLESGDTM-TINGHDHFPMQSVFKVPLAIAVLDQVD +KGKLSLDQVIHITKKELLPWSPIREKYPEGTMKLRELLTYTVSQSDNNGCDILFNLVGGT +AYVEQYIHGLGIDSIAIKANEERMAQAWKVQYTNWSSPLAMLQLLKGIHTGKYLSKSSNE +FLLKIMKETTTGPKRMRGMLPADAVVAHKTGSSDTAATNDAGIVTLPDGSHVAIVVFVSD +T---------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. s2p31 TaxID=1367557 RepID=A0A0B5E9G0_9PSED +----------TERASGTEVSYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEA---------------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas pruni TaxID=40683 RepID=UPI000A077C0F +-----ADLRALERRAQGRLGAYVLDPVRRVWF-GWRANERFAHCSSFKMSLAAMLLAKAD +RKEVDLAEVLHWTKAEMLSVSPVTETRIDTGLAVEDLAHAIVVTSDNTAANVLLRRFGGP +EQLTRFWRSIGDNVSRLDRYEPELNVTPPGTELDTTTPAAMAATTAALVHGKILSPASRA +KFMAWMREVRTGRDRIRSGFPAGWDSGDKTGTGIKHTYVDLAFGGPAGRTPLIVAAYFEP +ARPMDPVATGALAEVGRIAV--- +>[subseq from] Class A beta-lactamase n=1 Tax=Burkholderiales bacterium TaxID=1891238 RepID=A0A3S0FGV0_9BURK +---VRPELALLEPSVSGRLGFFAMDTGSGRTW-AHRADERFAMASTFKLLLAARVAEGVD +RGRWRWDDTVPLLATDRVPHAPAFDRLLPHGATLADLVQGLLVESDNPCANLLLRRCESP +AGLTAWLRTQGDDVTRLDRWETELNDNAPGDLRDTSTPRAFARSLQHLLLGPGLARASQA +RLWADMQASTTGLARLHAGVPAGWRVLDKTGTGGRGAVNDVGLVFPPGGAPWVVVALQSD +STAGTAALSAVVAGALRQLVKAw +>[subseq from] Class A beta-lactamase n=1 Tax=Mucilaginibacter sp. PPCGB 2223 TaxID=1886027 RepID=A0A1C2GQ64_9SPHI +--SLRNIIATIAQDAKGTVGFCMMNVETRDTL-SYNGRLHMPMQSVMKFPIAITVLNDID +EGRFTLDEKVHIEKDDLKPYSPLRDKFPQGNISIRELLSYMVSLSDNNACDILLKEIGGT +AHVENFMHSFGVKNIAVKATEFQMAQGWDVQYTNWTTAFEMARLLDIANKPNFLSKESHA +YLWKIMQETSTGPKQIKGLLPAGTIVAHKTGRSGTAATNDVGIITLPNGKHLVIAIFVSN +STVDLPTREDVMARITKAAWDY- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=A0A3N1KEN5_9GAMM +---VETEVARLATLVDGKVGVSAWRLDKGAQV-HLNPDEGFPMASTFKVAVAAVILSKVD +AGELALTTMVPVPKAFYVDSEVIADRFIHDGLSVHNLLEVMLTQSDNTATDVLVAQAGGP +AAVTAWLRAQGIEGQRLDRNTRQLLSAFDKDPRDTSTPRAMSTLLTRLFTGKALSPASTE +VLVQIMERCRTCSARLRGSLPPGTKVADKSGTVA-GTVNDVGVVTLPDGSQFAISVFVKA +SNAPRSERERVIAEIARTVR--- +>[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas sp. MYb238 TaxID=2040281 RepID=UPI001290C41A +--ALQAEAERLAAQLPGDVGAALVHLESGRAV-YVDADRPLPMASTMKVPVAVHILKLVD +EGKLGLQQQVLLGPDDIYPGGPM-DTHLSAGITIRDLLHMMITVSDNNATDILIRTGGGP +EAVQQRMRALGVDGLRVDRYIWELLAAWNADPRDTSSARAMAQLLQRTWKGELLSPASTR +VLQQIMLDTRTGNARLRGMLPSGTPVAHKTGTVGD-VINDVGVIELPNGRGHIVAAVFIR +SRASTEARDAAIAQLARAAHDYy +>[subseq from] class A beta-lactamase n=1 Tax=Gordonia effusa TaxID=263908 RepID=UPI00058AFAC0 +--AIEAQIRDAAAMSGAEIGVAAYDPATGATV-KVNSANRFPMLSTFKTYAVAEILRKHG +-IGARLDARVRITSADIVVNSPVTSAAVGTSMSLQELCIAALTRSDNTAGNLLLRDLGGP +TSIATTARRLGDDQSSLTRIEPDLNSAAPGDFRDTTTPDGLLSGYRQLLDGGAG-QHIST +QLLEWMRATKTSDQRTRAGLPAGWTTADKTGSGDYGTTNAAGVILTPSGKRLYLVIMTRD +ARSDAPAFNALLARVTQLL---- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. 357 TaxID=2555782 RepID=A0A3R8ZBN2_9CAUL +------DLSALEARHGGRLGVSVAT--EGLRA-AWRGDERFVYCSTFKMYLAAAILLRVQ +AGQERLDRAIPVTQADMIFHAPVTEPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL +DALRAFYRGIGDDSTRVDRLEPELNVA--EGDKDTITPDQSVRNIQRLLVDTPLSPESKA +LLMRWLVDSPSGPGRIKAGAPAGWTVAHKTGTGGGGPVNDIGLILPPNSAPIAIAVYFHA +TKSTNAQREAVIADATRQALK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7JA02_9BACT +--RLEQEVARLAPLAGGTVGVAAVHLESGREV-YFNRVEPFPMASTYKVPIAVQLLTRVD +QGEVRLDSLIALTPADLHPGSGTLTELFDDPLSLRNLLELMLLISDNSATDIVLRTAGGP +AAVTARMRALGFDGIRVDRPTAQLIARFNADPRDTATPETMARLLTRIWRKEILRPATSD +LLLDIMLRSTTGAERIKGLLPPDTPVSHKTGTIG-GTTNDVGIVTLPGDGHVVTVVFVKA +SDKEIPERERAIAHIARTIHDYf +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Bacteria TaxID=2 RepID=Q0PH70_SALTM +----------------------------------------FAMCSTSKVMAAAAVLKQSE +SDKTLLNQRVEIKKSDLINYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGKALAETQRA +QLVTWLKGNTTGSASIQAGLPTSWVVGDKTGSGDYGTTN--------------------- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Holophagales bacterium TaxID=2478486 RepID=A0A6B1GP73_9BACT +--HLGSEIERLAEASLGTVGVAAIHLESGRGV-LLNADERFPMASTYKVPIAVEILAQVD +AGKRSLDDLITMQTSDHVVTYGALSDFFDTPLTIQNVLGLMLRISDNIATDLLFREAGGA +EAITARMKASGVEGIRVDRTTRALIASFNSDPRDTATPRAMAALLRKIWKREILSEQSSA +LLIDIMARCETGENRIPGALPPGTPVAHKTGTIGE-STNDVGVITLPGDGHVISVVFVKE +SRPSNAAMEPVIAEIARASHDYf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D4Y823_9SPHN +-qDLAARISEIEKASGGRLGLGLHSPDKGLVY-AYRGDERFAMCSTFKLALAAMTLDTPG +----LREKRLHFGAGDILSYAPYAKERASSGMSGLEAAHHAVTLSDNTAANLLLAEVGGP +DGFTRWLRSMGDETTRLDRNEPALNENAPGDPRDTTTPTAHADLVGTLLWGDRHAQADRA +LLQEWLVETTTGMNRLRAGLPGEWRAGDKTGTCGQGEVNDIAMFETPDGSRYILAAYLDR +ADGSASDAEARLAEAARAIAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI00085C0BEE +----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP +--NNKLNKKIKINKQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA +LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ +DQKSAKPDDKIIAAVTEEAIK-- +>[subseq from] Beta-lactamase n=2 Tax=Staphylococcus TaxID=1279 RepID=K8DVY7_STAXY +--STNNDIEKLEKKYGANIGMYALNTQNSEAL-SFNENKRFAYASTLKAISSAMLLEQTP +--YNKLDKKIHINKDDIVPYSPVLEKYIGKEITIKKLIEATMLFSDNTANNKIIDELGGY +EHVKNRLTDLGDTTTHPSRKEPDLNFYSPKDKRDTTTPMAYGKSLNKLIVDGNLSKANKD +LLLDLMLKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVALVYPDGQKPIILVIFTNK +DKKDGKPNDKIVSEVAEIVLK-- +>[subseq from] Amo2 n=1 Tax=uncultured bacterium AOAmox2 TaxID=654971 RepID=D6MLV1_9BACT +-hDLRKSIQDIIRASGENVAVAIMGLEDKDTL-SVNGRIHCPMQSVYKLPLGMAVLKQVD +LGKLSLDQKIHITKKDLLPWSPLQKKYPEGNVPLSEILMYTVSQSDNSGCDILFRLLGGP +SNVEKYIHSLGVRGMAIATTEEEMHGDWNVQFSNWSEPVAMVQLLQLVHEDEVLSPSSND +FLLKLMTETTTGPNRIKGLLPKDAKVAHKTGTSGTAAINDAGIVTLPNGKHYAIAVFMLN +SRSDPKKLEAVIAAIAKSAWDHy +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Pelomonas TaxID=2638132 RepID=A0A0Q8GT19_9BURK +---TSAGFAALERRVQGRLGFFAIDTGSGRTL-GHRADERMAMASTFKILLAALVAEGVQ +AGRWGWNDAVPLREDERVPHSPAFDRLLPRGATLAELVQGIVVESDNPCANVLLRHCDTP +AGLTAWLRQQGDAVTRLDRWELALNENAPGDPRDTSTPRAFARTLQHLLLGSGLSRASQA +RLWADLQASRTGLKRLRAGVPAGWRVIDKTGTGYRGSVNDVALVFPPNGSPWVVVALQSD +STEPTDDLSAVHAEAMRQLVKAw +>[subseq from] class A beta-lactamase n=1 Tax=Nocardioides speluncae TaxID=2670337 RepID=UPI000D68B132 +-----DAIAEIEQRHDRRIGLYAVNLRTGREL-AHRPDERFAMCSTFKTLAVAAVLALVT +PDPHVLGRRAYYPPSMVTGYAARMQVWQEQGPTVAEVCEAAQSDSDNAAANWLLQQLGGP +DAITRLARELGDSVTTLTRWEPELNAWEPGQQIDTTTPRAMGGSYVELLLGRTLDGPDRR +RLTRWMLASRTGGAALRAGLPAGWRIAEKTGSGAYGTRNDVGIAWTDGDVPILISCLTRS +TEPGAPTVDAPLADVARHCA--- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus stepanovicii TaxID=643214 RepID=A0A0K2JNF9_9STAP +-nSTNNDIEKIEKKYGANVGMYALNTQNGKEL-SFNENKRFAYASTLKTISSAMLLEQTP +--YNKLDKKIHINKDDIVPYSPVLEKYIGKKITLKKLIEATMLVSDNTANNKIIDELGGY +EQVKTRLIDLGDSTTHPSRKEPNLNYYSPKDKRDTSTPLAYGKTLKKLISDGNLSKANKD +FLLDLMFKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVAFVYLDGQKPIILVIFTNK +DRKDGKPNDKIVSEVAEIVLK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Pasteurella sp. WM03 TaxID=2558280 RepID=A0A4Y9H1S2_9PAST +--DWKQTITQQEQKLKADIGVALLSSDGEVLF-EYQGNRAFPLNSTHKAFICGIALDLAE +DNALSFTQKLPIQATDIVSYSPITKN--KTTMNLAELCSAAVSYSDNTAANLIVKQIGGV +KAVSDYFKQHGLNKTRLDRREPEMNRDNLQKGLDLTTPIEAARLLHQFVFTDLLTAPSKM +LLTQWMLDDQVANDLLRSTLPEGWKIADKTGAGSHGSRSIISIFWKPDGTGYLLSIYLTN +TRATMAQRNQAIAEIGRVIFEQ- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacteria TaxID=2 RepID=A0A0U2ZT72_ECOLX +------------------------------------------MCSTSKVMAAAAVLKKSE +SEPNLLNRRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNHIA------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A355YAL8_9GAMM +--ALQAEAERLAAQLPGDVGAALVHLESGRAV-YVDGDRPLPMASTMKVPVAVHILKLVD +EGKLGLQQQVLLGPDDIYPGGPM-DTHLSAGITIRDLLHMMITVSDNNATDILIRTGGGP +EAVQQRMRALGVDGLRVDRYIWELLAAWNADPRDTSSARAMAQLLQRTWKGDLLSPESTR +VLQQIMLDTRTGNARLRGMLPSGTPVAHKTGTVGD-VINDVGVIELPNGRGHIVAAVFIR +SRASTEARDAAIAQLARAAHDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium camelliae TaxID=1265445 RepID=UPI000C1C8539 +-dNLKEKIQQIISSKDAEVGVAIKSQDGKDTL-SINGNRHFPLQSVFKFHIALAVLSQVD +KGKFSLNQKIKIGKKDLLPYSPIRDQYPNGVLPLSKILEYTVSQSDNVGCELLLKMIGGP +EAVEKYCKESGVKDISIKINEETQQANWDLQFQNWTTPKAGNEILELFYVNQLLSKKSYD +FIWKVMRETETGENRLRGQLPKTTVVAHKTGSSGTAAVNDMGIVFLPNGKHYFITVFVTK +SMENAETNEKIIADISKAAWDYf +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A0U3AZA5_ECOLX +------------------------------------------MCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKESDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNHIA------------------ +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SWU6_9BACT +------------------------------------------------------------ +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA +TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPSQAPLIAAIYLTQ +SDASMEQRNAAIAAIGAALAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Novosphingobium barchaimii TaxID=1420591 RepID=A0A561HSZ8_9SPHN +--TAAAALGRIEARAKGRLGAYVYDPARDRGF-GWRDEERFAHCSSFKLSLAAMMLAKGQ +RGEIDLDQLLHWSKADLLLHSPVTAEHVASGLTVRDLAHATLVTSDNAAANVLLSKFGGP +AELTRFWRGLGDSVSRLDRLEPELNTVPEGTELDTTTPAAMARTVAKLVLGHTLNPQNRQ +TLKDWMIEVETGRDRLRAGFPAGWIAGDKTGTGIRHTYVDLAFGGPAGRTPLFVAAYFEP +ANPMDPAALSALADVGRVAA--- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A519LCR2_9CAUL +------DFSELESRNGGRIGFAALRAGERPLV--WRVDERFVYCSTFKMYLAAATLLRVQ +AGHERLDRAIPITRADMLNHAPTTEPAIGSTLTVQQLMQGTVELSDNPAANILIREMGGL +DALRAFYRGIGDDSTRVDRLEPEMNRL--DGDKDTISPLQSVANIRHLLVDTPLSPASKT +LLTRWMIDTPTGQGRIKAGVPAGWTVAHKTGTGGYGPTNDIGVLTPPSGDPVVMAVYYHA +DRSSSDQNEAVIAEATRLALK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC46_STAAU +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DN--------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SBP5_9BACT +-dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKLD +KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD +FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000852B928 +----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT +--EKELNKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI +SSFKAALQQLGDHVSDPQRLEPKLNEYDPISTADTTTPRAAAQTLNELLTSHQMNTKNLK +LLKRVMIENETGDQLIKAGVPKDYLVGDKSGQGTYATRNDIAFIYPKDDKPIILAVYTKK +DDKEGTPDDKVIAKAAQIAIK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Dyadobacter jiangsuensis TaxID=1591085 RepID=A0A2P8FWX1_9BACT +--KLKFEIEDISRQAKGIVGVGVMDLKTKETL-LINQNHKFPMQSTFKFPLAIAVLNLVD +KGKLKLDQKIHVVRAELDQHSPMRDKHSKQDITIGELLSYSVSESDNNACDMLFELAGGT +KKVNDYIHSLGVKDIAIVATEKEMKAGWNVQYTNFARPSAYLQLLEIVYQGRTLSKSSHD +FLWKILVAGPTGLKRIKGLLPEGTVVAHKTGTSATAATNDVGIIKLQNKRDIAVVVFVSD +ATAKADTRELVIAQIAKAAADYy +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter mallensis TaxID=652787 RepID=A0A1H1R942_9SPHI +---LRDKIVELAKPAKGIVGVSVLGLEDRDTL-NYNGNSRLVMQSVMKFPIAMAVLHLVD +SGLFTLDKTIHIKKKDLPKYSPLRDKYPDGDVSLRDLLSYMVSQSDNDACDILLKFLGGP +DQVEYYLQNAKVRGINIEASEEDMAKKWEVQYTNWCKPRDMVKLIDVFYTGKALLPASKD +FLYTIMTETTTGPKRIKGLLPAGTVVAHKTGSSGTNATNDVGVITLPNGKHVAIAIFITN +STADEATRESVIANIAKAVYD-- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A5P5ZSA5_9FLAO +-qSLRTELENIIRGKKATVGVAVHKLDGSFNM-EINGKTRQPMQSVFKFHIALAVLDAVD +KGNLKLDQEIFIAEKDLLKWSPIRNKYPDGNLPLKEIIRYTVAESDNNGCDLLLRLIGGT +ESVQRFMDDKGITDFSIKANEEEMHRDWNVQYANYTTARSMNQVLKQFTLGKIVSPESTH +FLMNVMLNTKTGLNKIKEQLPPGTPVAHKTGSSGTGAENDAGIITLPSGEQYTLSVFVSD +SMETDAVNCRLISDLSKKVWQHf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI0009C1A468 +----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP +--NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA +LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ +DQKNAKPDDKIIAAAAKEAIK-- +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SBU7_9BACT +-dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKLD +KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD +FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium barchaimii TaxID=1420591 RepID=UPI0011BE0008 +--TAAAALGRIEARAKGRLGAYVYDPARDRGF-GWRDEERFAHCSSFKLSLAAMMLAKGQ +RGEIDLDQLLHWSKADLLLHSPVTAEHVASGLTVRDLAHATLVTSDNAAANVLLSKFGGP +AELTRFWRGLGDSVSRLDRLEPELNTVPEGTELDTTTPAAMARTVAKLVLGHTLNPQNRQ +TLKDWMIEVETGRDRLRAGFPAGWIAGDKTGTGIRHTYVDLAFGGPAGRTPLFVAAYFEP +ANPMDPAALSALADVGRVAA--- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium gallinarum TaxID=1324352 RepID=A0A0G3M9J5_9FLAO +-tTLEQKINAITKDKKATVGISVLGFENHFKY-SKNGEAKLPTLSVFKFHIACAVLNLVD +QGKLSLDQKIFIKKTDLPEWSPIREKYPDGNLSLNEVIDYTVALSDNNGCDLLLRLIGGT +QTVQQFMDSKGVKGFRIKHNEDDMHKNWKNQYGNYSTTNSAVQLLKKFYDGKILSRPSTD +YLMQIMLGTKTGTNKIVEQLPKGTPVAHKTGASGTVAENDMGIITLPDGKHYAIAVFVNN +SYESDVINCKIISDISKAVWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00061B18C1 +---VETEVARLATLIDGKVGVSAWRLDKGEQV-HLNPDEGFPMASTFKVAVAAVILTKVD +AGELALTTMVPVPKSFYVDSEVIADRFIHDGLSVHNLLEVMLTQSDNTATDVLVAQAGGP +AAVTAWLRAQGIEGQRLDRNTRQLLSAFDKDPRDTSTPRSMSTLLTRLFTGKALSPASTE +VLVQIMERCRTCSARLRGSLPPGTKVADKSGTVA-GTVNDVGVVTLPDGSQFAISVFVKA +SNAPRSERERVIAEIARTVRDFy +>[subseq from] class A beta-lactamase n=1 Tax=Legionella pneumophila TaxID=446 RepID=UPI0013751DC1 +---IDNKLQAIEREYHLKIGIYALDTNSGHVI-TYHANDRFPFQSTCKFIGVSALLASD- +--KSLLEKQVSISPKELLFWHPISGQYVNQKVSLRTLAEGAISYSDNTAINIIIRELGGL +GAINQFAHNIGNSSFKIAHYEVNLNSN-PKINEDSSTPKDMALSIKKIMLEDVLNNQNKV +LLLDWMRNNTTGYNRIRASVPLGWSVADKTGSGSYGIANDIGIVWSPACKPVILSIFTVS +NQSDAKPSDAVIAQITKAAFEEf +>[subseq from] Uncharacterized protein n=1 Tax=Agromyces aureus TaxID=453304 RepID=A0A191WG56_9MICO +hdRMSRELRSLERATSVTIGVHAVTQGERRSF-RYRAADRFPMCSLFKVLAAGALVQARG +YDEAYWATPIPFTDADVVRDSAVLATLQPQQATPEQLADAAIRFSDNTAGNLLLRELGGP +GAVTAFAASLGAGRTRLDRWEPELNDAVPGDVRDTTTPDDIALLYSALLLEDAAGVLASS +RLREWMLRTATSGARMRAGLTPPYELADKTGGGEYGVVNDAGVLWRPGREPLTLVILTRT +DRADAVRNNEVVAEATRIVV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Variovorax sp. p5 TaxID=1461284 RepID=A0A0B5EAU0_9BURK +----------------TRVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEA---------------------------------------------------- +----------------------- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WJV7_9BACT +-nELQKEIEQIAAAAKGRVGVEAVVLETGETA-SMNADAHFPMQSVYKFPIAMTALAQVD +AGRLKLEQKVRVEKSDFVRRSPVRDQNPQGVLSLMELLRYAVSESDGTASDVVLRVVGGA +DVVNKYLSDLQVSGLVVLNTEKEIGRDWETQYRNWASPEGAVSLLRALYDRRGLSEQSRA +LLLKLMTETPTGLKRLKGLLPKDAVVAHKTGTSGNAATNDIGIITLPNGRHLVIAVFVSD +SPADEATREGVIAKIARAAWD-- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00136413D0 +------------------------------------------------------------ +----------------LVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Shewanella aestuarii TaxID=1028752 RepID=UPI001425C2D8 +-kDVSAKLETISQKLVGRLGLAAQEIGSDERI-TVNGDEKFVMASTYKVAIAVALLERID +KGELKLSDLIDVPQETMVTGDGAIANHPGIKLSIANLIEPMITLSDNTATDICLKLAGGP +EAVTKVMRNIGITDLRVDRYTSEILRFEQEDLRDQSSPNAMLELLLAIDSGKVLSAQSSE +FLIDVMSRTRTGAGRLKALLPKGTPVAHKTGTIG-GVANDVGFITLPDGRRFAIVVYTKS +STTSEAERDRAIAEVTRILFDFy +>[subseq from] class A beta-lactamase n=1 Tax=Alphaproteobacteria TaxID=28211 RepID=UPI000829A4B3 +---LAAELRIIEAAGNGTLGVEIFNTATGASV-GINQDRRFGHASSFKFSLAALLLQRHA +AGTIDADRHVTWTEADMLSHAPFTRERLASGATLRELARATQTTSDNPAANILLRNLGGP +AGLTAFWRSLGDEVSRLDRFEPEMNVVPEAEFRDTTTPAAMARTVAKIVYGDVLPEKERA +ELKSWMVETETGLKRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEPPTGAPLTFACYFRA +RQTELASGQETLARVGRII---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=G5D8T4_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QIN--------------------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Chryseobacterium sp. (strain P1-3) TaxID=1517683 RepID=A0A086F9Y6_CHRP1 +-tTLEQKINAITKDKKATVGISVLGFENHFKY-SKNGEAKLPTLSVFKFHIACAVLNLVD +QGKLSLDQKIFIKKTDLPEWSPIREKYPDGNLSLNEVIDYTVALSDNNGCDLLLRLIGGT +QTVQQFMDSKGVKGFRIKHNEDDMHKNWKNQYGNYSTTNSAVQLLKKFYDGKILSRPSTD +YLMQIMLGTKTGTNKIVEQLPKGTPVAHKTGASGTVAENDMGIITLPDGKHYAIAVFVNN +SYESDVINCKIISDVSKAVWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter xixiisoli TaxID=1476466 RepID=UPI00137202ED +-----DALAELERQADGRLGAFIVDPARGQGF-GWREDERFSMCSTFKLSLAAMVLAMAD +HGELDPLHTLYWSKSDLVPHSPATEPALADGMTALDLARATLVLSDNTAANVLLREYGGP +AAMTRFWRAMGDDVSRLDRFETELNDTPPNTDYDTSTPAAMARTVSRLLLGAVLSPTARA +TLRQWMMAIETGLDRIRAGFPAGWIAGDKTGTGFRHTYGDLAFGGPSGATPLIIAAWFEP +SARIEPRDPGAIATLARV----- +>[subseq from] Beta-lactamase n=1 Tax=Dietzia timorensis TaxID=499555 RepID=A0A173LPD3_9ACTN +-qDLTARIVHMIDASEADVGVFAQSLDTRETV-EIGADESYPMLSTFKVYAVAAFLDRFG +-TSAALDDTVTIAEPDLVDNSPVTSENVGRPMSYRDLAIAALTRSDNTAGNLLLRKIGGP +AEIGEFAGRVGDSASRLDRWEVELNEATPGDERDSTTARGLAAGYRAVLDGDVLTPEARD +LLVGWMGETETSDKLSRAELPEGWTTADKSGGGYYGTRNTAGLVLGPEGQRILLVVLSRD +GKRDGPYAEQLISGIAA------ +>[subseq from] class A beta-lactamase n=1 Tax=Providencia sp. wls1914 TaxID=2675156 RepID=UPI0012B5D02E +--TLQEQVKQYEKE-GWKVGLSIL-FSNDKAI-SINGEQRFPLDSTVKSIACANALAKVD +AKKLLLSHSMIVTEENIVTYSPVAKDYMNKSFTLEQACKAANEYSDNTAANFAIFSGGGP +EALTAFMRAIGDTVTRSDRYEPELTVNPEGDLRDTTTPDAMSKSIKKILTGEVLSNSSKE +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASEYGVRGITSMVWSDNHEPVFISIYVRK +ADTSLDERSEVIRVLGSHIFDEy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pelomonas sp. HMWF004 TaxID=2056841 RepID=A0A2R7SRT3_9BURK +------ALLELERRAGGRLGVAVLDTVSGTQT-GLRRDERFGMCSTFKLPLAGLVLKAVD +EGRLALDQWVPYGEKDMVSHAPVTSQQLKAGMTVGALAEATQVTSDNPAANLLITLLGGP +AAITASLRALGDAHTRLDRMEPEMNGVPDGELRDTTTPAAMARTTARLLQSDWLSAASRE +RLAGWMVATQTGRKRLRAGLPTAWRAGDKTGTA--------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Agromyces aureus TaxID=453304 RepID=UPI000832757D +hdRMSRELRSLERATSVTIGVHAVTQGERRSF-RYRAADRFPMCSLFKVLAAGALVQARG +YDEAYWATPIPFTDADVVRDSAVLATLQPQQATPEQLADAAIRFSDNTAGNLLLRELGGP +GAVTAFAASLGAGRTRLDRWEPELNDAVPGDVRDTTTPDDIALLYSALLLEDAAGVLASS +RLREWMLRTATSGARMRAGLTPPYELADKTGGGEYGVVNDAGVLWRPGREPLTLVILTRT +DRADAVRNNEVVAEATRIVV--- +>[subseq from] Uncharacterized protein n=1 Tax=Rhizobium oryzae TaxID=464029 RepID=A0A1Q9B1C9_9RHIZ +-----ARLRAAERKAGVRLGAFVLDTERGRSF-GWRADERFCHCSTFKFSLAALALREAD +AGRLDPAEMLAFSRRDIIAYSPVVEDHLAAGLSILALAEAVQVTSDNAAANILMRRLGGP +EALTRFWREIGDDKSRLDGYEPAINIIPVGTEENSTTPRAMAGTVQRIVLGDVLSAESRQ +RLRAWMSATKTGLTRLRGGIPATWQGLDKTGTGMRRKTNDLAVLFPPGGKPLVIAAYVEN +PAETRPQDEALLRTLAELAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000D1E9505 +----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP +--NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA +LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ +DQKNAKPDDKVIAAAAEEAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI0004F6752E +----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP +--NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA +LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ +DQKNAKPDDKVIAAAAEEAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000D1D529A +----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP +--NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA +LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ +DQKNAKPDDKVIAAAAEEAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000D1D2E14 +----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP +--NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA +LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ +DQKNAKPDDKVIAAAAEEAIK-- +>[subseq from] Uncharacterized protein n=1 Tax=Rodentibacter genomosp. 1 TaxID=1908264 RepID=A0A1V3J9P0_9PAST +--DWKQTITQQEQKLKADIGVALLSSDGKVLF-EYQGNRAFPLNSTHKAFICGIALDLAE +DNALSFTQKLPIQATDIVSYSPVTKN--KTTMNLAELCSAAVSYSDNTAANLIVKQIGGV +KAISDYFKQHGLNKTRLDRREPEMNRDNLQKGLDLTTPIEAARLLHQFVFTDLLTAPSKM +LLTQWMLDDQVANDLLRSTLPEGWKIADKTGAGSHGSRSIISIFWKPDGTGYLLSIYLTN +TRATMAQRNQAIAEIGRVIFEQ- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. OV279 TaxID=1500285 RepID=A0A1M4YM06_9FLAO +---LEQKINSITEGKNATVGVSVLGFENNFKY-SKKGGHPLPTLSVFKFHIACAVLDLVD +QGKLSLDQKLFIKKEDMLEWSPIREKYPDANLTLSEVLDYTVALSDNNGCDVLLRLIGGP +QTVQKFMDSKGVKGFQIKHNEAEMHKSWKALYENYSTPNSAIQVLKKFYDGKLLSKKSTD +YLMQIMLGTKTGTNKIVEQLPKNTPVAHKTGSSGKNAENDMGIITLPNGKHYAIAVFVND +SMETDAVNCKMVSDISKAVWDDf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A173DSP5_ECOLX +------------------------------------------MCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDGQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNHIA------------------ +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Legionella pneumophila TaxID=446 RepID=A0A2S6F4X4_LEGPN +-----NKLQAIEREHHLKVGLYALDTNSGHVI-TYHANDRFPFQSTCKFIGVSALLASD- +--KPLLEKKVSVSSKELIFWSPISGQYVNQKVPLKTLAAGAISYSDNTAINIIIRELGGL +GSINQFAHHIGNSSFKIAHYEVNLNSN-PKINEDTSTPKDMALSIKKIMLEDVLTNQNKA +LLLDWMRNNTTGYNRIRAGVPLGWSVADKTGSGSYGIANDIGIVWSPACKPVVLSIFTVS +NQSNAKSSDEAIAQITKAAFEEf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=A0A385JC04_SALTM +----------------------------------------FAMCSTSKVMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTT---------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000D1D9551 +----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT +--EKELNKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI +SSFKAALQQLGDHVSDPQRLEPKLNEYDPISTADTTTPRAAAHTLNELLTSHQMNTKNLK +LLKRVMIENETGDQLIKAGVPKDYLVGDKSGQGTYATRNDIAFIYPKDDKPIILAVYTKK +DDKEGTPDDKVIAKAAQIAIK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Altererythrobacter sp. Ery1 TaxID=2306995 RepID=A0A418NE88_9SPHN +-------LRIIEAQGNGTLGVAVLDTGTGRVW-GHADYARFPHLSSFKLSLAALVLHLDE +TGALDAGEHVTWTEDDLLSYAPFAKERLEEGATLRELAEFTQKLSDNTAANVLLRRLGGP +ERLTAFWRAIGDETSRLDRYEPELNLVPPGEIKDTTTPTAMARTLGKLLYGDALGEAARA +TLKLWMAETRTGTKRVRAGLPPEWPSGDKTGTSLGSVYVDVGYVEPPARAPLTFAAYFRA +ARAADPASEAVLAEVGRVIAR-- +>[subseq from] Beta-lactamase n=2 Tax=Serratia marcescens TaxID=615 RepID=A0A0B6VPP7_SERMA +-dSLKNSIEKYLKDKKAKVGVAVLGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKLD +KENISVDKKLFVKKSDLQPWSPLKDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD +FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. BLS98 TaxID=885586 RepID=A0A0J7I778_9FLAO +-sALEQKINSITEDKKATVGISVLGFENNFRL-SKNGDKPLPTLSVFKFHIACAVLDLVD +QGKLSLEQKLFFKKEDMLEWSPIREKYPEASLSLGEVLDYTVALSDNNGCDLLLKLIGGT +QTVQKFMDSKGVKGFQIKRNEDDMHKNWKTQYDNFSTANSAVQVLKKFYDGKLLSKKSTD +YLMQIMLGTKTGTNKIVEQLPKNTPVAHKTGASGNGAENDMGIVTLPDGKHYAIAIFVNN +SIETDEVNCRIVSDISKAVWDDf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000406CC41 +----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP +--NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA +LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAIYTNQ +DQKNAKPDDKIIAAAAKEAIK-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WSB9_9BACT +---LERAIKRLAESSGGIVGVSAIHIESGRRV-SVNGDLRFPMASVYKLPIALRLLQRID +RGELRLDDPITLSTHDFRPHSPIAEFANNKPLPLERLLELMLGESDNSASDLLLRLAGGP +AAVTNRMQALGIMGINVSRPEGQLILAYADDPRDTSTPDAMADLLVRIHRRDVLEPASME +RLLQITTATQTGPARLKGLLPIGTVVAHKTGTMG-GTTNDVGIVTLPDGGHLAIAVFVKA +STKDVPERERAIAELARTVYDFf +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus lentus TaxID=42858 RepID=A0A5F0TU92_STALE +----NSAIDKIEKKYDANVGMYALNTQNGEEL-SFNEDKRFAYASTLKAVSSAMLLEKVP +--SNKLDKKIHISKDDIVTYSPVLEKYVDKEITLKKLIEANMLYSDNIANNKVIDELGGY +KEVKKRLVDLGDTMTYPSRKEPDLNLYTPKDKRDTTTPSAFGKTLNKLIIDGNLSKSNKD +FLMNLMLKNKSGDTLIKDGAPSDFKVMDKSGQATYGSRNDVAFIYPKGQKPIILVIFTNK +NNKDAKPNDKIVSEVAEEVLK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Erythrobacter sp. 34-65-8 TaxID=1970335 RepID=A0A259JYF5_9SPHN +------RLRIIEAGANGVLGASFHDTGTGETV-SHNGFARFPHASSFKLSLAAMVLARDR +AGVIDADRLVRWTRADLMSYSPFTTERLEQGATLRELARATQTTSDNAAANALLRELGGP +EALTAFWRSLGDETSRLDRIEPELNLVPPGDLRDTTTPDAMARTVAALLYGPVLDAPRKA +ELRQWLIETRTGLDRVRAGLPPEWPAGDKTGTSLGSVYVDVGFVEPAGRAPITFAVYFRA +AQQHDPAALAAMAETGRVL---- +>[subseq from] class A beta-lactamase n=1 Tax=Maribellus sp. Y2-1-60 TaxID=2696285 RepID=UPI001431DA23 +--AISRKIEKISEGLVGRIGVAAQEIGSKEMI-TVNGDEQFVMASTYKVAIAVALLDRID +KGELKLTDLIDVEQETMVTGDGAIANHPGIKLSVANLIEPMITLSDNTATDACLKLAGGP +EAVTKMMRSIGITELRVDRYTSEILRFEQEDPRDQCSPYAMLQLLLAIDSGKALSEKSRE +FLLATMSRTRTGDGRLKGLLPKRTPVAHKTGTIG-GVANDVGFVTLPDGRRFAIVVFTKS +STTSEANRDRAIAEVTRTLYDFy +>[subseq from] Uncharacterized protein n=1 Tax=Stenotrophomonas sp. Leaf70 TaxID=1736233 RepID=A0A0Q4QWE8_9GAMM +--ALQAEAERLAAQLPGEVGAALVHLESGRAV-YVNGDRPLPMASTMKVPVAVHILKLVD +EGKLGLQQQVLLGPDDIYPGGPM-DTHLSAGITIRDLLHMMITVSDNNATDILVRTGGGP +EAVQQRMRALGVDGLRVDRYIWELLAAWNADPRDTSSARAMAQLLQRTWKGELLSPESTR +VLQQIMLDTRTGNARLRGMLPSGTPVAHKTGTVGD-VINDVGVIELPNGRGHVVTTVFIK +SRASTEARDAAIAQLARAAHDYy +>[subseq from] class A beta-lactamase n=3 Tax=Acidomonas methanolica TaxID=437 RepID=UPI00104A3C6A +-----ARLRAVEQTSGGRLGAFVLDIGSGRSF-GWRADERFCHCSTFKLSLAAMVLRESD +VGRLDLTETLSFSKADIVGYSPVVEENLAAGLSILALAKAVQITSDNAAANVLMRRLGGP +EAVTRFWREIGDDTSRLDGYEPSVNVIPPGTEANSTTPHAMADTVHRIVLGDVLSKGSRE +RLQAWMAATRSGQNRIRAGIPADWRGYDKTGTGMGNKTNDLAVLVPPGGSPLVVIGYFEN +PVAIRPADEAVLKRLGEVA---- +>[subseq from] class A beta-lactamase n=1 Tax=Micrococcus luteus TaxID=1270 RepID=UPI00069D22E7 +--HLDRALADLERQSSRKIAVTIGD-GEHQLY-SYRGTDPMPMCSLFKTILVGALLHDHA +YDEAFWNQKITFTKGEVVVNSPICSADADGVMTVDELADAALRWSDNTAGNLLLRLYGGP +AQLTAYAASLGMRQTRLDRWEPELNTAIPGDLRDTSTTNDMEKGFSDLLVGSALTQAGRA +RLRSWMLRNQTSGKRLRANLPATMELADKTGAGDYGVVNDAGVYWSGEE-TLSIAVMTRA +SFAGAMNDNTVVARIGQLAVQHy +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000C31E8FC +----ASEIEHIEQEKNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP +--NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA +LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYKDKQKPIILAVYTKQ +DQKNAKPDDKIIAAAAEEAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI00049AFA65 +----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP +--NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA +LLKQFMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAIYTNQ +DQKNAKPDDKIIAAAAKEAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000623E4F7 +----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS +--EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV +KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNKILTSDQISDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIFLAIYTKQ +DDKDGQPDDKVIADAAEEAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas halotolerans TaxID=69670 RepID=UPI000F4AD346 +------DLSALEAANGGRIGLAAHDLASGLRL-ASRGEERFVYCSTFKMYLAAATFLRVQ +AGEEDLARPIPITRADMVSHAPVTEPAIGQSLTVEQLCKGTVEVSDNPAANLLLKANGGL +ETMQDFYRRLGDTSTRVDRFEPEMNRL--DGDKDTIIPLQSIANIKRLFIDDPLMVPHRD +KLLGWMFASPTGEGRIKAGLPAGWRTAHKTGTGGYGPTNDIGVLYPPTGEPVVLAIYYHA +TRSSAEQNDAVVAEATRLAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Larkinella sp. C7 TaxID=2576607 RepID=UPI0011112B7C +-qRLNQELERIAKLAKGKVGLCAVHLESGKQV-SMNLQERFPMASTVKVAIAVELLTKIE +KGELSLRTMVDLKPSDLHPGSGTLETLFAKPLSVENLLELMMVISDNSATDILLNLVGGV +EPVRARLKALGIQGMSVDRTIVELIAKLEQDPRDTSTPEAMVNLLTQIYQAKALKPESRD +LLLAVMERCRGGLARIKGYLPPATVVAHKTGSLNSSATDDVGIITLPGDGHIVIAVFITA +SSQAAAEREQTIAHLSRTVYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Nocardioides litoris TaxID=1926648 RepID=UPI00111CE4A0 +--SLDPELTALEAERGTTIGLVARHRGTGREL-RHRPDARQPLCSTFKPLVAAALLVRGD +----CLDRVVRYDERDLVEYAPITGERR--AMTVGELADAAIRFSDNPAGNLLLRRLGGP +AALTAFLRRTGDRVTRLDRFETELNSAVPGDPRDTTTPRALAATYERLVCGDVLDARDRW +VLRGWLQSSTTSVDRFRSGLPAGWWCADKTGSGSYGVANDAGVVTAPDGTELVFAIQTRR +STTDATSDPTLMAALARLLV--- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. JM1 TaxID=1233950 RepID=A0A086AXZ1_9FLAO +---LEQKINSITEGKKATVGVSVLGFENNFKY-SKNGDQPLPTLSVFKFHIACVVLDLVD +KGKLSLDQKLFFKKEDMLEWSPIREKYPDANLPLSEVLDYTVALSDNNGCDVLLRLIGGT +QTVQKFMDSKGVKGFQIKHNEAEMHKSWKALYENYSTPNSAVQVLKKFYDGKLLSKKSTD +YLMQIMLRTKTGTNKIVEQLPKNTPVAHKTGSSGKNAENDMGIITLPNGKHYAIAVFVND +SMETDAVNCKMVSDISKAVWDDf +>[subseq from] class A beta-lactamase n=1 Tax=Agaribacterium haliotis TaxID=2013869 RepID=UPI000BB5554B +----ATRIQALEQG-QARLGVCLLDTVTGEVT-GNRLDERFATCSTFKLAMVAACLREAD +HGRLNLDEILPYSEGDLLPWAPVTKKHLAEGLSIKTLAQAAQQWSDGVAANLLVKRLGGP +AAVTAKYRDMGDTVTRLDRYEPDLGLVLSADMRDTTSPLAYAQLVARILTADVLRDTTRK +QLLAWTQSTATGARRLRAGLPVEWQTGNKTGTGRTNKCNDVAITFPPGKNPIIIAAYFDS +GEKIEARHEAVLAEVGKIAAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A349Y3Q7_9GAMM +---VETEVARLATLVDGKVGVSAWRLDKGAQV-HLNPDEAFPMASTFKVAVAAVILTKVD +AGELALTTMVPVPKSFYVDSEVIADRFIHDGLSVHNLLEVMLTQSDNTATDVLVAQAGGQ +AAVTAWLRAQGIEGQRLDRNTRQLLSAFDKDPRDTSTPRAMSTLLTRLFTGKALSPASTE +VLVQIMERCRTCSARLRGSLPPGTKVADKSGTVA-GTVNDVGVVTLPDGSQFAISVFVKA +SNAPRSERERVIAEIARTVRDFy +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter marinus TaxID=538382 RepID=UPI001360EF51 +--------NILETAANGTLGVAVLDTGTGALW-GHNDYARFPQLSSFKLSLAALVLHLDE +RGDIDADERIGWGADELLDHAPFARERLGGGATLRELAEATQKLSDNTAANVLLRRLGGP +ARLTAFWRAIGDEASRLDRTEPDLNAVPPGEIRDTTTPAAAAQMLGRLLYGDALGAGARA +TLKAWMADTRTGQRRVRAGLPAEWPAGDKTGTSLGSVYVDVGFVEPPGAAPLTFATYFRA +ARQHDPAAEGVLAEVGRVIAR-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A5N8AM03_9SPHN +---LAFPLSRLEQQAGGRLGFAIFDSSNGRSI-GINANDRFAFCSTFKMPLAAMTLEALD +KARLPADQLLPVTQADITTYAPITSKAIDIGMTARDLAAAAVIHSDNVAANILLAALGGP +AGFTHWLRAQGDAITRLDDIEPALNSVPAGSAENTTTPMAMARLFARLLGQSPLPPPSRE +QLGQWLRDSQTGLARLRAGLPADWKVGDKTGTASTGKVNDVAAIWHPDGHIITIAAFYEV +PLAMPADNDAVLAEAAKAACQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000853315F +----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS +--EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV +KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKDGQPDDKVIADAAEEAI--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC44_STAAU +----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDS----------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Halieaceae bacterium GH4-78 TaxID=2547392 RepID=A0A4R5LTP0_9GAMM +---VAAAIEQFAAKLVGRIGFAAQEIGSDEVI-ALNGDETFPMASTYKVAIATAILDRVD +REELSLDQMVEITPDMMMIDAALSDTFVHPGLSVANLMEIMITESDNTATDTLMGQAGGP +AAVTENLRRLGITDFRVDRLTGEIIGDFEADPRDHATPLAMLKLLLAIDSGTATSAESRD +FLIDVMSRTRTGAGRLKGLLPKGTPVAHKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS +SETSEANRDRAIAEVARSLYDYy +>[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas sp. Y8 TaxID=2591145 RepID=UPI0011C7C642 +----EVDLTTLERSTGYRVGVYARDTGSGDTV-TYRADERFGYASTLKALAAGEVLAGQP +--ASVLDRPLTVTAEDVADHAPVTADAAGTDLTIGALGGAAVSDSDNGALNVLLRHLGGP +AALQAALAARGDATTRVDAAEPELNRFTPGAPARTSTPRALAEGLATYALGDALGPAVRE +AYVGWLTASTTGLDAVRAGTPDGWVVGDKTGTAGFGSRNDVAVLWPPGRAPIVLAVLTDH +PDEAAEPDDAVLAAAARSVLAAy +>[subseq from] Beta-lactamase n=4 Tax=Staphylococcus TaxID=1279 RepID=J9HBE3_9STAP +----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS +--EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV +KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKDGQPDDKVIADAAEEAI--- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Planctomycetes bacterium Pla144 TaxID=2528003 RepID=A0A5C6CZF7_9BACT +-kDISQKIEKVTQGMVGRIGVAAQEIGGNEVI-AVNGDETFAMASTYKVAIATTVLDRVD +KGELSLDQLVEVQPDMYVTVTALAETFPHPGLSVANLIEVMITESDNTATDVCMELAGGA +AAVTKNLRRLGITDFRVDRTTREILMDFEADPRDHTTPLAMLKLLLAIDGGKAMSPESSK +FLLGVMSRTRTGAGRLKGLLPKGASVAHKTGTAG-GIANDVGYVTLPDGRRFAIAVFTNS +SKTPVADRDRAIAEVGRTLYDFy +>[subseq from] Beta-lactamase n=2 Tax=root TaxID=1 RepID=A0A656AYH1_VIBCL +------------------------------------------------------------ +----------------MVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A3C1RJ36_9FLAO +-sSLETQINSIIKNKKATVGISVLGFENGFTY-NKNADKKLPMQSVFKFHIAAAVLDYAE +KGKLSLDQKVTLNQSNLHEWSPLREKYPNGAVSLSEIIEYTVAKSDNNGCDILLKLLGGT +QVVQKFMNAKGVKNFQIKYNEEAMHKDWNAQYENYSTTNSAVDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGTNKLIEQLPKDTPIARKTGSSGTGAENEIAIITLPNGKHYAIAVFVSN +STETAEVNCRMISDISKTIWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000E69C92C +------GFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS +--EKDLNKKITINETDIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV +KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNKILTSDQISDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDNHKPIILAIYTKQ +DDKDGQPDDKVIADAAEEAI--- +>[subseq from] Uncharacterized protein n=1 Tax=Methylobacterium sp. SCN 67-24 TaxID=1660110 RepID=A0A1E4DK24_9RHIZ +--RLDAGIKSIEQTAKGRLGVALLDLRDRKSW-SHRGTEPFPMQSVFKLPLAVAVLQAVE +AGKLKLDQKITVTRNDLSLHSPLAKGFKGERYTLRDLLTRSTAESDNTAADLLLRLIGGP +QVLTAMLRDGGVPGISVDRYERVFQPASLKDRRDAASPDASAAFLEAFAKGNWLREPATT +LLDKIMLETKTGQQRIRAGLPQGARFAHKTGLGPNHATNDIGIVTLPDGRRFAIAVYLAG +SQADAKAREAAHAAVARLAVE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Altererythrobacter sp. AY-3R TaxID=2268576 RepID=A0A4Q2KJ72_9SPHN +-------LRIIEAQGNGTLGVAVLDTGTGRVW-GHADYARFPHLSSFKLSLAALVLHLDE +TGAIDAGEHVTWSTDDLLAYAPFARERLEQGATLRELAEFTQKLSDNTAANLLLRRLGGP +ERLTAFWRALGDETSRLDRYEPELNLVPPGEIKDTTTPAAMARTLGKLLYGDALGEAARA +TLKLWMADTHTGTKRVRAGLPPEWPAGDKTGTSLGSVYVDVGYVEPPARAPLTFAAYFRA +ARAADAASEAVLAEVGRVIAR-- +>[subseq from] Beta-lactamase n=1 Tax=Providencia rettgeri TaxID=587 RepID=A0A2A5PZC8_PRORE +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWSPMMEEHPGDEVAVQQLLQYSVSHSDNVACDLLFELVGGP +AALDAYIRSIGVKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQVAQAAYQ-- +>[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium aubagnense TaxID=319707 RepID=A0A5R8SCY4_9MYCO +-----SSLANVEQRHGGRLGVFALDTGSGRTL-AWRADERFLMCSTFKGLLAGQILARVD +AGQEQLDRLVPYTEHDLIFTSPVTQVNVTHGLPVGTLLDAILEQSDNTAAVLLMRSAGGP +AGLTEFVRQLGDNVTRSDRYEPESNNT--NGVLDTTSPRAIVTTAQRLLLDDVLGPSSRA +ILEQGMVNCKPGLNRLRAALPDGWQGADRPGTSIEKETNDYLLARPPGAAPLLIAAYYDA +PGKPLAEREAVLREVGGLFV--- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000D1D4893 +----ASELKHIEQENDVTIGVYGMNTDNGKVY-KHNADERFAFASTYKAIASGILLNNMP +--NGKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNNELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLASKQMDKDNQA +LLKQVMIENETGDSLIKAGVPKEYTVGDKSGQATYGTRNDLAFIYTDHRKPIILAVYTKQ +DQKNAKPDDKIIAAAAKEAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas terrae TaxID=363631 RepID=UPI00141F17DC +------DLSALEQRFDGRMGFAFAT--EGKRG-AWRGDERFVYCSTFKMYLAAATLVRAQ +TGSEDLDRAIAITPADMLEHAPVTEKAIGKTLTITQLMKGTVEESDNPAANILIREMGGL +DAMRQFYRDIGDATTRVDRMEPEMNRW-D-GDKDTILPSQSVRNLEKLFLSEALKPESKR +LLLEWMVATPTGQGRMKAGAPSDWTVAHKTGSGGYGPVNDIGILYPVEGAPIVVAAYFHG +SASSNDQREAAIAEATRQ----- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SCR7_9BACT +-dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKLD +KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWSTPDATVQLLKKFYKNEILSKNSYD +FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D9XBU6_9SPHN +--------SEIETASGGRLGLALHSPDKGLVY-AYRGDERFAMCSTFKLALAALTLDTPG +----LREKRLHFGAGDILSYAPYAKERASSGMSGLEAAHHAVTLSDNTAANLLLAEVGGP +DGFTRWLRSMGDETTRLDRNEPALNENAPGDPRDTTTPTAHADLVGTLLWGDRLAQADRA +LLQEWLVETTTGMNRLRAGLPGEWRAGDKTGTCGQGEVNDIAMFETPDGSRYILAAYLDR +ADGSASDAEARLAEAARAIAD-- +>[subseq from] Serine hydrolase n=1 Tax=Caulobacter mirabilis TaxID=69666 RepID=A0A2D2ASR5_9CAUL +--ATERRLAELSRAQPGVLGVYVEDLATGWSA-GVEADAPRPMMSVFKAPMAAAVLAQVD +AGALSLEHKVTIRKEDLRGGPTIVADQFKGEFTVRELLGYAVSQSDNTATDALLPLIGGP +PAVTAYMRGKGIEGFRLDRDERALGAGFMADPRDTVTPRAAGAFLRQLAAGELVSPASTA +LLLDLMRKTTTGPRRIRVGMPTGSQLAHKTGGSGAIATNDIGLVTTPDGRRLAVAIFLSA +SPANDKERDALIAEAARIA---- +>[subseq from] Beta-lactamase n=2 Tax=Pedobacter nyackensis TaxID=475255 RepID=A0A1W2ENY8_9SPHI +-nKLQQRMESIINGKKADVGVSVLYLENKRSV-SVNGDKHYPMQSVYKFHLALAVLDQVD +KGKFKLNEKIFVKKSDLLPWSPLRDKYPGGNVALTEIIKFTVSASDNNGCDILFRLLGGP +NKVHQYIAGLGIKDCEITATEEEMHNDDKVQFRNWTTPKSANALLEKFCNGKVLKKHTGD +FLMKVMEETTTGPNKIKGLLPPGTVVAHKTGFSGTAASNDVGIVTLRNGKKMIISVFVSM +SKESEKENEKIIAELAKAAWE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A519HFU9_9CAUL +------DFSALETRNGGRLGFVALDMERGASV-GWRAAERFVYCSTFKMYLAAATFVRIQ +DGRETADRMIPITRADMVNHAPVTEPAIGSSLSVDRLMQAVVEVSDNPAANLLLKANGGI +EAMQNFYRSIGDDSTTVNRFEPEMNRL--DGDKDTIQPAQSVANLQRLFLDPALTTDSQA +RLLRWMFESPTGADRLKGGAPTGWQVAHKTGTGGYGPTNDIGLLYPPTGKPVIVAAYYHA +TSTSAAANDAVIADATRLALK-- +>[subseq from] Beta-lactamase n=2 Tax=Vibrio vulnificus TaxID=672 RepID=A0A3Q0L135_VIBVU +-kDVSQKLETISQRLVGRIGVAAQEIGSGERI-TVNGDEMFVMASTYKVAIAVALLERID +KGELKLSDLIDVPQETMVTGDGAIANHPGIKLSIANLIEPMITLSDNTATDICLKLAGGP +EAVTKVMRNIGITDLRVDRYTSEILRFEQEDLRDQSSPNAMLELLLAIDSGKVLSEKSSE +FLLDVMSRTRTGAGRLKGLLPKGTLVAHKTGTIG-GVANDVGFVTLPDGRRFAIVVYSKS +STTSEADRDLAIAEITRTLYDFy +>[subseq from] Beta-lactamase n=1 Tax=Vibrio vulnificus (strain CMCP6) TaxID=216895 RepID=A0A3Q0KYQ0_VIBVU +-kDVSQKLETISQRLVGRIGVAAQEIGSGERI-TVNGDEMFVMASTYKVAIAVALLERID +KGELKLSDLIDVPQETMVTGDGAIANHPGIKLSIANLIEPMITLSDNTATDICLKLAGGP +EAVTKVMRNIGITDLRVDRYTSEILRFEQEDLRDQSSPNAMLELLLAIDSGKVLSEKSSE +FLLDVMSRTRTGAGRLKGLLPKGTLVAHKTGTIG-GVANDVGFVTLPDGRRFAIVVYSKS +STTSEADRDLAIAEITRTLYDFy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SBA9_9BACT +-dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLYKLD +KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD +FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] Beta-lactamase n=1 Tax=Runella sp. SP2 TaxID=2268026 RepID=A0A3G3GJ90_9BACT +---LRQRLQRVASTTQGMLGIGVVDLSNGDTV-SVNGQGRFAMQSVYKFHLALAVLSEVD +RGKWTLEQKIKVTKKDLLPWSPLREKYPNGELPLREILEYTVAQSDNNGCDILFRLMGGT +KVVDKYIKSIGINEVNIVGTEEEMHADERVQFDNWSTPRSAAKLLEVFHQKKILSKNSWD +FLWNTLVGTTTGPRKLKGQLPQGTIVAHKTGYSGQGATNDIGIVQLPNGKRFAIAVFLNN +TSLPEAECDRAIAEAAKVAWDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Myroides injenensis TaxID=1183151 RepID=UPI00028A13C2 +---LRNKIEQILSDKNAVVGVSIIGNNGKDTL-SLHGDRRFPMQSVFKFHIALAVLSEID +KGKLSLDQKIEIRKDELLPWSPLRDENPNGGFTIERLIQYSVSHSDNTACDVLIRLIGTP +KTVEEYIKKSGINDIQITFNEEDMQSKWENMFQNWTTPKAASQTLKLFYDNNLLSKSSYD +FFWKTNKETTTGNNRIKGQLPEGTVVAHKTGSSGTAAVNNIGIVFLPNGEHFIISVFVSE +SKENFDTNEKIIADIAKATYDFy +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonadales bacterium BRH_c3 TaxID=1734408 RepID=A0A101V795_9SPHN +--RLAARLRIIEAAAGGTLGVALYESGSGRTL-AHRGDELFAHCSSFKLSLAAMLLHHDE +AGKIDAGEHVRWSAQELMSVSPFTKRRLEEGATLLELARATQTLGDNAAANILLKRLGGP +QALTEFWRTLGDPVSRLDRYEPDLNQVPPGEVRDTTSPLAMARTLEQILHGDVLNPANAA +LLMQWMSETRTGARRVRAGLPQDWQSGDKTGTSIDAIYVDIGFAHVPGGARYTFATYYRA +AREMDPAAEAVLAQVGGVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Acetobacter farinalis TaxID=1260984 RepID=UPI001408209D +-----ARLRALEQATGGRLGAFVLDTGSGHSF-GWRFDERFCHCSTFKLSLAAMALRASD +AGHLDLMEPLPFSKEDIIAYSPVVEKNLARGLPILKLAEAVQITSDNAAANVLMRRLGGP +AAVTRFWREIGDKTSRLDSYEPDVNVIPPGTEKNSTTPQAMAETVRKIVLGDVLSATSRE +QLRGWMAATQSGRNRIRAGIPDSWRGLDKTGTGMGNKTNDLAVLLPPDRSPLIVIGYFET +PVNIRPEDESVLRTLGEIAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium soldanellicola TaxID=311333 RepID=A0A1H1FLZ5_9FLAO +-pALDQQINSILKDKKATVGISVSGFENGFKY-SKNADKKLPMQSVFKFHIATAVLDFVD +KGKLSLNQKILLDQSNLLEWSPLRDKYPNGNVSLSEILDFTVAQSDNNGCDIMLKLLGGP +QTVQKFMDSKGVKNFQIKYNEEAMHKDWNAQYENYSTTASITDVLRKFFDGKLLSKKSTD +YLMKVMLGTKTGTNKLVEQLPKNTPVAHKTGASGTGAENDMGIITLPNGKHYAITVFVSN +STETDAVNCKIISDVSKVVWDHf +>[subseq from] Beta-lactamase n=7 Tax=Bacteria TaxID=2 RepID=P74842_SALTM +---LKEQIETIVTGKKATVGVAVWGPDDLEPL-LLNPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQSVTVNRAAVLQWSPMMKDHQGDEVAVQQLLQYSVSHSDNVACDLLFELVGGP +QALHAYIQSLGVKEAAVVANEAQMHADDQVQYQNWTSMKAAAQVLQKFEQKKQLSETSQA +LLWKWMVETTTGPQRLKGLLPAGTIVAHKTGTSGTAATNDAGVIMLPDGRPLLVAVFVKD +SAESERTNEAIIAQVAQAAYQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI0007047F31 +----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS +--EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV +KGFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKDGQPDDKVIADAAEEAI--- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium gallinarum TaxID=1324352 RepID=UPI00143D0D34 +-tTLEQKINAITKDKKATVGISVLGFENHFKY-SKNGEAKLPTLSVFKFHIACAVLNLVD +QGKLSLDQKIFIKKTDLPEWSPIREKYPDGNLSLNEVIDYTVALSDNNGCDLLLRLIGGT +QTVQQFMDSKGVKGFRIKHNEDDMHKNWKNQYGNYSTTNSAVQLLKKFYDGKILSRPSTD +YLMQIMLGTKTGTNKIVEQLPKGTPVAHKTGASGTVAENDMGIIMLPDGKHYAIAVFVNN +SYESDVINCKIISDVSKAVWDYf +>[subseq from] Beta-lactamase (Fragment) n=26 Tax=Bacteria TaxID=2 RepID=Q2FC64_STAAU +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DN--------------------- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Riemerella anatipestifer TaxID=34085 RepID=UPI0012B30A30 +---LRNKIEQILSDKNAVVGVSIIGNNGKDTL-SLNGDKRFPMQSVFKFHIALAVLSEID +KGKLSLDQKIEISKDELLPWSPLRDENPNGGFTIERLIQYSVSHSDNTACDVLIRLIGTP +KTVEEYIKKSGINDIQITYNEEQMQAKWENMFQNWTTPKAASQTLKLFYENKLLSQSSYD +FFWKTNKETTTGKNRIRGQLPEGTVVAHKTGWSGTAAVNNIGIVFLPNGEYFIISVFVSE +SKEDFDTNEKIIADIAKATYDFy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A346QRV3_ECOLX +----------------------------------------FAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARRLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTT---------------------- +----------------------- +>[subseq from] Beta-lactamase class A n=2 Tax=Pelomonas sp. BT06 TaxID=2135721 RepID=A0A397S288_9BURK +-----PDFAALERRVQGRLGFFALDTGSGRTL-AHRADERFAIASTFKILLGARVAHGVE +VGRWSWDDKVPLHESQRVPHSPAFDRFLPRGATLAELVQGIVVESDNPCANVLLRHCESP +AGLTAWLREQGDQVTRLDRWETELNENAPRDPRDTSTPRAFAQTLQHLLLGPGLARTSQA +RLWADLQASRTGLKRLRAGVPARWRVIDKTGSGARGAVNDVALVFPPSRAPWVVVAFQSD +AKAAIDELNAVHADAVRLLVQAw +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000C34A732 +---SASEIKHIEDKNDVTIGVYGMNTENGKIY-KHNADERFAFASTYKAIASGILLNNTS +--QDKLNKKVKINEQDIVAYSPVTEKYIGKTMSLKSLVKASMLQSDNTANNKIIKEIGGI +KGFNKELKNLGDATSKPQRLEPELNNYDPTKIADTTTPKAAATTLNKLLSSSQMDKENQT +LLKQVMVENETGDSLIKAGVPKHYTVGDKSGQATYGTRNDLAFIYTDEHKPIILAIYTKQ +SQKNAKPDDKIIAAAAEKAIE-- +>[subseq from] Beta-lactamase n=3 Tax=Pedobacter antarcticus TaxID=34086 RepID=A0A081PCI6_9SPHI +hnVLRQKAEELVKSKPAAIGFSIINLKTGDTL-SVNGEKHLPMQSVYKFHLALAVLKQVD +QNKFTLDQKILVKKKDLLPWSPLRDKYPGGNLPLSEILFYTVAQSDNNGCDILFRLLGGP +EIVNKYIHSLGIKDVEIRSTEEQMHADDQLQFKNWTTANAATQLLKRFYMGQLLKQPTND +FLMKIMAGTTTGTGKLKGKLPTGTEVAHKTGYSGQNATNDIGIITLPDGTHFAIAIFVSM +TALDEKASDQIIAELAKLSWDEf +>[subseq from] Beta-lactamase n=2 Tax=Chitinophaga flava TaxID=2259036 RepID=A0A365XUK5_9BACT +--PLTKKFEEIAAGSKGTVGVCATILETGETV-GLNSKMRFPMQSVYKFPIAMAVLDQVD +RGKLSMQQQIRVLPSDYIPHSPLRDEHPAGNVSITELLRYNVAESDGSACDVLLRVIGGV +KVADKYVHRLGIKDMRIALTEQVQVPNEPMQYQNWSTPEAMTALFKKFYTGHVLSDSSYH +YLLDILVNSAPGARRLKAQLPKGTVVAHKTGTSGTRATNDAGIITLPDGKHLIITVFIKD +SYADQETRERTIASISKAAWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Arthrobacter sp. 9E14 TaxID=2058887 RepID=UPI000CE320B1 +--HLDRSIAALESANGVTIGIAAGR--RGQTAyTYRGGDTFPMCSLFKTLAVARLLRDHA +YDDEFWKRRILFREDQIVENSIICAADEDRDMSVEQLADAALRFSDNTAGNLLLELIGGP +MQIGAYARTLGAPSTRLDRWEPELNEALPGDLRDTSTPSDIHKLYEALLIGDALSTLGQA +CLRSWMLRNTTAGKRLGAAVSPGTELADKTGAGDYGVVNDAGVVWPDGRPPLTVAVMTKT +DDPDAVNNNEVVARVGQLIFA-- +>[subseq from] Uncharacterized protein n=1 Tax=Xanthomonadaceae bacterium SCN 69-123 TaxID=1660170 RepID=A0A1E4KXA8_9GAMM +--ALQAEAERLAAQLPGDVGAALVHLESGRAV-YLNADQPLPMASTMKVPVAVHILKLVD +EGKLGLQQQVLLGPEDIYPGGPM-DTHLSAGITIRDLLHMMITVSDNNATDILVRTGGGP +EAVQQRMRALGVDGLRVDRYIWELLAAWNADPRDTSSARAMAQLLQRTWKGEILSPASTG +VLQQIMLDTRTGSARLRGMLPSGTPVAHKTGTVGD-VINDVGVIELPNGRGHVVATVFIR +SRASSEARDAAIAQLARAAHDYy +>[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter sp. YT40 TaxID=2547601 RepID=A0A4Y6VWW2_9SPHN +---LAAELRIIEAAGDGTLGVELYNTATGQSV-GLNSDRRFGMASTFKLSLAALLLQRDA +TGTVDADRRVTWSEAEVLSYAPFARERIATGASLRELARAAQVVSDNTAANILLRELGGP +AALTAFWRSIGDEVSRLDRIEPELNIVPPTEFRDTTTPAAMARNVAKLVYGDVLPEAERA +ELRGWMIATQTGLTRVRAGLPEGWVAGDKTGISGEGNYNDIGFAEGPKGGPITFACYFRA +RGETMKARDLALSRIGRII---- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000C32AD59 +---SASEIKHIEDKNDVTIGVYGMNTENGKVY-KHNADERFAFASTYKAIASGILLNNTS +--QDKLNKKVKINEQDIVAYSPVTEKYIGKTMSLKSLVKASMLQSDNTANNKIIKEIGGI +KGFNKELKNLGDATSKPQRLEPELNNYDPTKIADTTTPKAAATTLNKLLSSSQMDKENQT +LLKQVMVENETGDSLIKAGVPKHYTVGDKSGQATYGTRNDLAFIYTDEHKPIILAIYTKQ +SQKNAKPDDKIIAAAAEKAIE-- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. CC-CTC003 TaxID=2565924 RepID=A0A4S4A4X9_9FLAO +---LSVQFQEIVKDKKATVGIAVYNFTTKDTV-TFNNTPDYPTLSVYKFHVALAVLHLVD +QGKLRLDQDIFVKKSELLEHSPLRENYPYGNIKLSELLSYMVALSDNNACDILFRLAGGT +KKVDRYIKNLKIKDTRITATEEEMHLKWENQYLNTTSPLAAVQLLQQFYQMKILSPTSYD +YLLNVMLGTKTGPDKLKGLLPKDILVAHKTGSSFKAAENDIGIVFLPGGQTYAIAVFVKN +SMEDDTTNNTIIAKVSKAVFDHy +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga eiseniae TaxID=634771 RepID=A0A1T4N6E5_9BACT +--NLSQQFETIAQAAKGTVGVSVLVLETGETA-GLNSKIRFPMQSVYKFPIAMAVLHQVD +KGKLKLEQPVRVLPSDYIPHSPLRDKYPAGNITVAELLRYNVAESDGSACDVLLRIIGGT +AVADRYIHDLGIKNIRIALTEQVQVPNEPMQYQNWSTPEAMTALFRKFYTGHVLSGSSYD +FLLDLLVNSGPGARRLKAQLPKGTVVAHKTGTSGTRATNDAGIITLPDGHHLIITVFVKD +AYADQETREKTIANTAKAAWDHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=bacterium p7 TaxID=1560477 RepID=A0A0B5E3B9_9BACT +--------------ADSRVSYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEA---------------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Leadbetterella byssophila (strain DSM 17132 / JCM 16389 / KACC 11308 / NBRC 106382 / 4M15) TaxID=649349 RepID=E4RZ35_LEAB4 +--DFDQEVTALAKGKDLKVGVALIDLKTGEIK-QVNGDDPFPLQSVFKFHIAAKALEQVD +KGKWQLRDQISIEPGEIYTYSPIRDEIGTNLMRLDSLIYYMVSLSDNSACDILLRHLGGP +STVNEYIKEIGIKNTKIEVNELTMQSRWEEQYRNISTPLSVAETLKKFYLREYLSGDMHD +FLWALMENSPTGANRIRKGLPEGAVLAHKTGTSGSGATNDAGIIILPDGRAYVLVVFVSD +SKESDEVNEELIAKIAELI---- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=A0A1B1G4D2_9STAP +------GFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS +--EKDLNKKITINKADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV +KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKDGQPDDKVIADAAEEAI--- +>[subseq from] Uncharacterized protein n=1 Tax=Rhizobium taibaishanense TaxID=887144 RepID=A0A1Q9A9A0_9RHIZ +---SASKLRELEQKAHGRLGAYVLDPVRGTAF-GWRENEHFTHASSFKMSLAAMLLAKAD +AGQIDLDEILHWTKDDMLPVSPLTKANLDKGLSVRDLGRATLVTSDNTAANVLMRRFGGP +SQLTAFWRSIGDTVSRLDRYEPDLNDTPPGTDLDTTTPAAMAATTAAFVHGNVLSAGSRA +MLRAWMTDVKTGRDRIRSSFPVDWVSGDKTGTGIKHTYVDLAFGGPAGRGPLIVTAYFEP +IRPMDKNAVAVLAAVGHIVAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium wanjuense TaxID=356305 RepID=A0A1I0P0G3_9FLAO +-sALDQKISSIIKNKKATVGVSVLGFENGFIY-NKNGDKKLPMQSVFKFHIAAAVLDFVD +KGKLSLDQKIVLDKSNLLEWSPLRDKYPNGGVPLSEIIEFTVAKSDNNGCDILLKLIGGT +QTVQKFIDSKGIKGFQIKYNEEEMHKDWNTQYQNYSTTASAVQTLKKFYDGKLLSKKSTD +YLMKIMISTSTGLNKIVEQLPKNTVVARKTGASGTGAENEIAIITLPNGKHYALAVFVSN +STETDAVNCKMISDISKTVWDYf +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. T22 TaxID=2203219 RepID=A0A2Z3N1N4_9BACT +--SLYRQIAGIAEAAGGEVGVAARNLDGGPLL-QYRDSVRYPMHSVFKFPIAMAILHQVD +EGKLQLHQPIYIHQKWMVPWSPLRDSFPKGNKPLSELLALMVSQSDNIACDILIDLAGGE +AAINDYVRSLGITDINIAASEAKMASAWDVQFSNWAYPSAMVQLLDVLNKGAVLTKTSND +FLWKIMIETSTGPRRIKGLLPPDVVVAHKTGTGGTSATNDAGIIFMPGGQKLAITVFITN +SRADEATREGVIAKITKLIYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Rathayibacter sp. Leaf299 TaxID=1736328 RepID=A0A0Q5BVV0_9MICO +--AIDAALAADEAEYDARIGLVAVDTEDERTL-EHRADERFRSASSIKALAAGALLARTE +--PADLERVVTW--SDVVDHSPVTGPATATGLPLGEVAEAAVRLSDNTAHNVVLQELGGP +AGLQEALRALGDDVTRVDRIEPELNRVSPE-GLDTGTARSLAADLRALLLGDALDPADRA +QLRDWMSGNATGDALVRAGAPDGWSVLDKSGGAG-GLRNDLAVVERPGAAPIVIAVLTER +RDPSLPYDDALVARAASVALE-- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium luteum TaxID=421531 RepID=A0A085Z0A8_9FLAO +-sALEQKINSITEGKKATVGISVLGFENNFKY-SKNGDQKLPMLSVFKFHIAAAALDLVD +KGKLSLDQKVFVSKTDLKEWSPFREKYPAGNVTLNEVIDYTVALSDNNLCDLLLKLIGGT +KKVQQFMDSKGVKDFQIRYNEQEMHENWKSLYENYTTPNSAAQVLKKFYDGKLLSKKSTD +YLMKIMTGTKTGTNKIIEQLPKNTPTAHKTGSSGKNAENDIGIITLPNGKHYAIAVFVSN +STEADAVNCKMVSDISKAVWDDf +>[subseq from] Class A beta-lactamase n=1 Tax=Altererythrobacter sp. FM1 TaxID=2484537 RepID=A0A3N2QFV5_9SPHN +--RLTAKLRLIEVGSGGTLGVMLLNTADGQAI-GHNSGERFAMCSTFKASLAALALDRAA +KGALDLDKVLHWRESDLQSYAPFAKERLATGATIRELARAAQVLSDNTAANLVLGAVGGP +SVLTQFWRSLGDDVSRLDNIEPLLNVVLPGRLENTTTPDAMARTLAKILFGGGVAPQAAQ +TLQQWMRETQTGTKKVRAGLPAEWVAGDKTGFSGQGVSADIGFAIPSDGAPIVFATYHRA +TTPPSPMADAAMSQVGGVI---- +>[subseq from] Beta-lactamase n=1 Tax=Providencia alcalifaciens TaxID=126385 RepID=Q8RK40_9GAMM +-----------------------IKFPDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD +AKKLSLSHSMIVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP +EALTAFMRAIGDTVTRSDRYEPELTVNPEGDLRDTTTPDAMSKSIKKILTGEVLSHSSKE +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK +ADTSLDERSEVIRVLGSHILDEy +>[subseq from] Beta-lactamase class A n=1 Tax=Agromyces sp. OV429 TaxID=2135464 RepID=A0A3D9PEH0_9MICO +--RMTRDLHDLERATSVTIGVHAVGHGDRRAF-RYRGADVFPMCSLFKVLAAAALVRDRG +YDEGYWATPIPFTDADIVRDSLVLATLQPQQATPGQLADAALRYSDNTAGNLLLRELGGP +AAITSFAASLGANRTRLDRWEPELNEAVPGDVRDTTTPDDIALLYAALLLEDAAGVLASS +RLREWMLRNTTSGARMRAGLTAPYELADKTGGGEYGVVNDAGVLWRGGRDPLTLVILTRT +DRPDAVRNNEVIAEATRIVV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Siphonobacter aquaeclarae TaxID=563176 RepID=A0A1G9I621_9BACT +--SLRTKIEQITKGRKATVGVGIHAFRDGQTL-TINRNRHLPMQSVYKFHVALAVLKEVD +KGRFRLDQNMHVKKSDYVPHSPMSEAYPGGNLPLADIIRFMVADSDGSACDYLFRLLGGP +VRVNTVIHELGIQGVAIRNTEEMMQANWDVQYSNWTTPVAMLDLMKLFYQRKILSTRSYD +FLWKVMTETTTGQNRLKKRLPAGTVVAHKTGTSGTGAVNDVGFISLPDGSCIAVSVFVTN +STESMEANEQLIADIAKAAYDHf +>[subseq from] Class A beta-lactamase n=1 Tax=Actinosynnema pretiosum TaxID=42197 RepID=A0A290Z441_9PSEU +------ELAALEERHGARLGVRVVDTGSGAAA-GHRADERFPVCSLVSAYAAGALLVAND +WADGFFQQVITYERAELIGNSPVTGARVDGGMTVAELCDAAIAHDDSTALNELLSLVGGP +EAITAFAFALGDEQTRLDRWEPDLNAAEPGDERDTSTPAALAAGYRNLVLGTALEARERA +ELRGWLEGGGT---VLRSVVPRGWAVGGKPGAAEYGTRCDAAIAWPPDRDPLVVVLMSTR +PERDARADGTLLADAARVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI00049B0802 +----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP +--NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA +LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ +DQKNAKPDDKVIAVAAEEAIK-- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=A0A418IHK4_STAXY +---SASEIKHIEDKNDVTIGVYGMNTENGKVY-KHNADERFAFASTYKAIVSGILLNNTS +--QDKLNKKVKINEQDIVAYSPVTEKYIGKTMSLKSLVKASMLQSDNTANNKIIKEIGGI +KGFNKELKNLGDATSKPQRLEPELNNYDPTKIADTTTPKAAATTLNKLLSSSQMDKENQT +LLKQVMVENETGDSLIKAGVPKHYKVGDKSGQATYGTRNDLAFIYTDEHKPIILAIYTKQ +GQKNAKPDDKIIAAAAEKAIE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium taibaishanense TaxID=887144 RepID=UPI000A071022 +---SASKLRELEQKAHGRLGAYVLDPVRGTAF-GWRENEHFTHASSFKMSLAAMLLAKAD +AGQIDLDEILHWTKDDMLPVSPLTKANLDKGLSVRDLGRATLVTSDNTAANVLMRRFGGP +SQLTAFWRSIGDTVSRLDRYEPDLNDTPPGTDLDTTTPAAMAATTAAFVHGNVLSAGSRA +MLRAWMTDVKTGRDRIRSSFPVDWVSGDKTGTGIKHTYVDLAFGGPAGRGPLIVTAYFEP +IRPMDKNAVAVLAAVGHIVAE-- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Blastocatellia bacterium TaxID=2052146 RepID=A0A352FGR9_9BACT +-qELQNQINQIAALAKGRVGVSAVVLETGETVaALNSQDHFPMQSIYKLPISMAVMKQVD +AGKIKLEQKVKVAKEDYVGHSPIRDKYRDGVLTVNELLRFALSESDGTASDVLMKLAGGP +GAIQAYLTELGIKDMIVLDTEQSFIQDHSLQYRNFATPGAAVALLRALYEHRGLSESSQA +LVLKFMTESTTGPKRLKGLLPAGTNVAHKTGTSGTAATNDIGIITLPGGAHAAIAVFISD +SPADEATREGTIAKIAKAVWD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SBR6_9BACT +-dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKLD +KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKISYD +FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=Q5W3A6_9BACT +-dSLEQRINSIISGKKASVGVAVAGIEDNFSL-SINGKKNFPMMSVYKLHIVLAVLNKVD +GGSLKLDEKIPLNKKDLHPWSPLRDKYPNGGIPLSEIIEYTITQSDNNGCDILIALAGGT +EAVKRYIISKGISDFDIRATEKECHESWNVQYSNWSTPVSAVALLKKFNDRKILSSVSTE +YLMNVMIHTSTGNKRIKGLIPPSADVAHKTGTSGTPGTNDIGIVTLPNGKHFAIAVFVSD +SRENNAANERIIAEISKAAWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI00034CE293 +---SASELKHIEQENDVTIGVYGMNTDNGKVY-KHNSDERFAFASTYKAIASGVLLNNVP +--NGKLNKKIKINERDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIIDEIGGI +EGFNNELQGLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLASNQMDKDNQA +LLKQVMIENETGDSLIKAGVPKQYIVGDKSGQGTYGTRNDLAFIYTDHRKPIILAVYTKQ +DQKNAKPDDKIIAAAAEEAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI0011A0F176 +----ASEIEHIEQEKNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP +--NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNKELKSLGDYISKLQRLEPDLNDYDPTKIADTTTPKAAATNLNKLLTSKQMDKGNKT +LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYKDKQKPIILAVYTKQ +DQKNAKPDDKIIAAAAEEAIK-- +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga cymbidii TaxID=1096750 RepID=A0A512RIS7_9BACT +-dSLRNEIAAIAARSGGTVGVGIMNLHTRDTL-NFQNDPVYPMQSVFKFPIAMAILHQVD +EGKMKLEQKIYIDKKWMVPWSPLRDAFPDGNQTLAQLLEYMVSQSDNIACDLLIDLAGGE +AAINDYVHGLGVKQIAIVASEAKMASAWDVQFTNFCAPSAMVQLLDILHKGSALSKTSND +FLWDIMLKTSTGPKRLKGLLPVGTPVAHKTGTSGAAATNDAGIIVLPNGQKLAIVVYVMN +ARSDEATREATIAQIAKAAYDK- +>[subseq from] Uncharacterized protein n=1 Tax=Stenotrophomonas terrae TaxID=405446 RepID=A0A0R0CBK8_9GAMM +--GLQTEAQRLAALLPGQLGAAIVHLESGRSV-YLDADRPFPMASTMKVPVAVHILKLVD +EGKLSLQQQVTLDADDVYPMGGPMDLHLSAGITVRDLLHMMITVSDNNATDILIRLGGGT +TAVNARMQALGITGMRVDRYIWELLAAWNEDPRDTSSALAMTTLLQKVWRGEVLQPASTR +LLQDIMLDTRTGTARLRGMLPKETPVAHKTGTVGD-VINDVGVITLPGGHGHAIVSVFVQ +SRASNEERDAAIAQLARAAHDYf +>[subseq from] Serine hydrolase n=1 Tax=Larkinella sp. ZZJ9 TaxID=2315727 RepID=A0A368JTG3_9BACT +-qRLNQELERIAKLAKGKVGLCAVHLESGKQI-SMNLQERFPMASTVKVAIAVELLTKIE +KGELSLRTMVDLKPSDLHPGSGTLETLFAKPLSVENLLELMMVISDNSATDILLNLVGGV +EPVRARLKALGIQGMSVDRTIVELIAKLEQDPRDTSTPEAMVNLLTQIYQAKALKPESRD +LLLAVMERCRGGLARIKGYLPPATVVAHKTGSLNSSATDDVGIITLPGDGHIVIAVFITA +SSQASAEREQTIAHLSRTVYDYf +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. VAUSW3 TaxID=2010998 RepID=A0A219AEI5_9FLAO +-qNLKKEILQITKGKNATVAVSVLDFENNKSV-HIRGNAKLPMLSVFKFHIALAVLNEVD +RGKLDLDQKIFIKKSDLLEWSPIRERFPEGNIPLRELIKYTVAESDNNGCDILLRLIGGT +ETVQKFISSKGIKNFTIKADEEQMHKSFEFMYLNVTTTNSANQLLQDFFNKKIVSKTSTD +FLMTTMLGTSTGRNKIVAQLPENIPVAHKTGSSGKNAENDIGIVTLPDGRHYAISIFVSD +SMESEATNTKMIADISKIVFDYf +>[subseq from] Uncharacterized protein n=1 Tax=Rodentibacter sp. Ppn85 TaxID=1908525 RepID=A0A1V3JZS3_9PAST +-tEWQQTITQQEQKLKADIGVALLSAEGKVLF-EYQGNRAFPLNSTHKAFVCGIALDLSE +DNLLSFNYQFPIQSSDIVSYSPITQHK--TAMSLTELCSAAVSYSDNTAANLIVKQIGGV +KVVSNYFKRQGLTQTRLDRTEPEMNRDNLKKGLDLTTPIEAVQLLHQFIFGDLLTQASKV +RLTQWMLDDQVANDLLRSTLPRDWKIADKTGAGSHGSRSIISVFWKPDGTAYLLSIYLTN +TQATMEQRNQAIAEIGKAIFDQ- +>[subseq from] Beta-lactamase n=2 Tax=Staphylococcus TaxID=1279 RepID=A0A2T4QH63_STAXY +----ASELKHIEQENDVTIGVYGMNTDNGKVY-KHNADERFAFASTYKAIASGILLNNMP +--NGKLNKKIKINEQDMVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNNELKGLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLASNQMDKDNQA +LLKQVMIENETGDSLIKAGVPKAYTVGDKSGQGTYGTRNDLAFIYTDHRKPIILAVYTKQ +DQKNAEPDDKIIAAAAKEAIK-- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus pseudoxylosus TaxID=2282419 RepID=A0A3M2QEZ1_9STAP +----ASELKHIEQENDVTIGVYGMNTDNGKVY-KHNADERFAFASTYKAIASGILLNNMP +--NGKLNKKIKINEQDMVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNNELKGLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLASNQMDKDNQA +LLKQVMIENETGDSLIKAGVPKAYTVGDKSGQGTYGTRNDLAFIYTDHRKPIILAVYTKQ +DQKNAEPDDKIIAAAAKEAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000853E70D +----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS +--DKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV +KGFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKDGQPDDKVIADAAEEAI--- +>[subseq from] VEB-PER_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059XDP4_9BACT +--DLQTQITSISQSIIADIGVAVIDVQSNDTL-SVNGNKHFPMQSVFKFHIALAALRQVD +EGKLSLDQKYHVTKDHYFNWSVLMREHPEANVTLRELITWCVMNSDNVACDLLFEILGGP +SHVDKFIKSLNVNDIAITANERKMHTDWYEQFSNWTTPSATARLLRLFYDGKILKDDSNK +FLWKLMADTPNAPNRLKGLLPEGTVVARKPGTGALGAANDVGILVLPNGKKIIVAAFVTN +TKEPLSTAEMAIAQISKAVYDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Pedobacter sp. L105 TaxID=1641871 RepID=UPI00131BEEC9 +-eALQAKLQSVINAHQAIIGFSLMDLQNGDTL-TINGAKHLPMQSVFKFHLALAILNQVD +QGKLRLDQKILIRKSDLMPWSPLRDKYPNGEIPLSELLRVTVAESDNNGCDLLFRLIGGP +AKVNAYIHSLGVKEIAITATEHEMHHNEQAQFTNWTTARAATQLLKLFYSKHLLSASSQE +FLWNVMTGTTRISTKIKGQLPAGTPVAHKTGYSGTAASNDIGVVTLPNGKHFALAVFVSM +TKEDEKTIDATIAELTKTSWDY- +>[subseq from] Class A beta-lactamase n=1 Tax=Novosphingobium sp. P6W TaxID=1609758 RepID=A0A2Z5E9W6_9SPHN +-----DALRATEARAGGRLGAYILDPARGSGV-GWRENERFAHCSSFKMSLAAMILAGAE +RGEIDLGEVLRWSAQDLLPHSPVTSGAVDSGLSVKALAHATLVTSDNTAANVLLRRFGGP +AQLTRFWRSLGDKVSRLDRYEPELNRIPPGSEFDTTTPAAMAATMARLLLGDRLTPQGRG +TLKSWMTEVQTGSDRIRAGFPAGWTSGDKTGTGGQQTYVDLAFGGPANVPPLIVACYLET +SRDTKG----------------- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000D1EC286 +---SASEIKHIEDKNDVTIGVYGMNTENGKVY-KHNADERFAFASTYKAIASGILLNNTS +--QDKLNKKVKINEQDIVAYSPVTEKYIGKTMSLKSLVKASMLQSDNTANNKIIKEIGGI +KGFNKELKNLGDATSKPQRLEPELNNYDPAKIADTTTPKAAATTLNKLLSSSQMDKENQT +LLKQVMVENETGDSLIKAGVPKHYTVGDKSGQATYGTRNDLAFIYTDEHKPIILAIYTKQ +GQKNAKPDDKIIAAAAEKAIE-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flectobacillus major TaxID=103 RepID=UPI00042713D4 +---LKQQIEQFLATKKAKVGVSVVGIESKEAF-AVNATGHYPLQSVFKFHLALAVLNQVD +KGILQLNQKIVVKKNDLLLWSPIREAYPAGDIPLSEILKYTVALSDNNGCDILLRLIGGP +KVLNTYLHKLGIKDVAITVNEEDMQKDWDTQFTNWSTPKAATDLLLMFYRHQILSQSSFD +FLWRTMVETTTGKKRIKGQLPEGTIVAHKTGTSGTAAVNDIGIVTLPNNQHFAISIFVAN +SKENTDTNEQIIAEITQLTWAYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Spirosoma aerolatum TaxID=1211326 RepID=UPI0009ACAEC7 +--SVRQQIQHIVAGKKATVGIALMSDDGKDTA-SIYGNRHFPLQSVFKFHIALAMLSQID +QGKFSLDQPIKIQKKDLLPYSPIRDKYPNGTMNLSEMLAYTVSQSDNVGCDLLLKLLGGP +EAVERYIKQSGTNDISIKVNEETQQANWDLQFKNWTTPRAAVNVLQTFYVNKRLSTQSHD +FIWTVMKGTQTGQARLKGQLPKQTIVAHKTGSSGTAAVNDIGIVFLPNGRYYFISVFVKD +SRENEDTNEKLIADIGKATWDYf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WHU1_9BACT +---LERAIKRLAESSGGIVGVSAIHIESGRRV-SVNGSLRFPMASVYKLPIALRVLQRVD +RGELRLNAPVTLSTHDFRPHSPIVEFANNKPLPLERLLELMLGESDNSASDALLRLAGGP +AAVTNRMQALGIMGINVSRPEGQLILAYADDPRDTSTPDAMADLLVRIHRRDVLEPASME +RLLQITTATQTGPARLKGLLPIGTVVAHKTGTMG-GTTNDVGIVTLPDDGHLAIAVFVKA +STKDVPERERAIAEIARTVYDFf +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium mucoviscidosis TaxID=1945581 RepID=A0A202CD88_9FLAO +-sSLDTQINSIIKNKKATVGISVLGFENGFTY-NKNADKKLPMQSVFKFHIAIAVLDYAD +KGKLSLDQKVTLNQSNLHEWSPLREKYPNGGVPLSEVIEYTVAKSDNNGCDILLKLLGGT +QVVQKFMNAKGVKNFQTKYNEEAMHKDWNAQYENYSTTNSAVDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGTNKLIEQLPKDTPIARKTGSSGTGAENEIAIITLPNGKHYAIAVFVSN +STETAEVNCRMISDISKTVWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas terrae TaxID=405446 RepID=UPI000A441A45 +--GLQTEAQRLAALLPGQLGAAIVHLESGRSV-YLDADRPFPMASTMKVPVAVHILKLVD +EGKLSLQQQVTLDADDVYPMGGPMDLHLSAGITVRDLLHMMITVSDNNATDILIRLGGGT +TAVNARMQALGITGMRVDRYIWELLAAWNEDPRDTSSALAMTTLLQKVWRGEVLQPASTR +LLQDIMLDTRTGTARLRGMLPKETPVAHKTGTVGD-VINDVGVITLPGGHGHAIVSVFVQ +SRASNEERDAAIAQLARAAHDYf +>[subseq from] Beta-lactamase n=2 Tax=Chitinophaga ginsengisegetis TaxID=393003 RepID=A0A1T5PCG6_9BACT +-qTLRQQIAGIAGNISGKVGVYAEILETKDTV-SFNRDQHFPMQSVYKFPIAMAMLHQVD +QHKFRLDQPIHVTKDDLIGVSPVRDQHPEGNMPLGELIDYNIRASDGSACDVLLRLLGGT +AKANAYVHSLGVKQLAISTTEKVQVPSEMIQYKNWSTPMAMTQLLKIFYQEPVLSDSSKN +YLMHLMVTSRPGAKRLKGLLPAGTVVAHKTGTSWTRATNDVGIITLPNGHHLAITVFVSD +AKASEEEREGAIAKIAKAAYDHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=M9UY78_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKAYT-------------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Riemerella anatipestifer TaxID=34085 RepID=UPI0007EDECC2 +---LRNKIEQILSDKNAVVGVSIIGNNGKDTL-SLHGDRRFPMQSVFKFHIALAVLSEID +KGKLSLDQKIEIRKDELLPWSPLRDENPNGGFTIERLIQYSVSHSDNTACDVLIRLIGTP +KTVEEYIKKSGINDIQITFNEEDMQSKWENMFQNWTTPKAASQTLKLFYDNNLLSKSSYD +FFWKTNKETTTGNNRIKGQLPEGTVVAHKTGSSGTAAVNNIGIVFLPNGEHFIISVFVSE +SKENFDMNEKIIADIAKATYDFy +>[subseq from] Beta-lactamase n=1 Tax=Pedobacter sp. OV280 TaxID=2135471 RepID=A0A3E0ETF4_9SPHI +-qDLKKAIETIANKHTAKIGFAVIDLQNGDAI-GFNGTVHYPMQSVYKFHLALAVLKQVD +EGKLKLDQQILVKAKDLLPWSPLRDKYPQGNIPLTEILGYTVSQSDNNGCDILFRLVGGP +AKVNQFINSIGLKDVAIVATEEEMHLDEKVQFKNWSTSFSAVQLLKMFYEKKILSKSSGD +FLWDIMVKTVSGPNKIKGLLPKGTIVAHKTGSSGTTASNDIGIVALPNGKHFAIAVFVSM +TKEEEKVTDQIIAECSKAAWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio vulnificus TaxID=672 RepID=UPI001033EEC6 +-kDVSQKLETISQRLVGRIGVAAQEIGSGERI-TVNGDEMFVMASTYKVAIAVALLERID +KGELKLSDLIDVPQETMVTGDGAIANHPGIKLSIANLIEPMITLSDNTATDICLKLAGGP +EAVTKVMRNIGITDLRVDRYTSEILRFEQEDLRDQSSPNAMLELLLAIDSGKVLSEKSSE +FLLDVMSRTRTGAGRLKGLLPKGTLVAHKTGTIG-GVANDVGFVTLPDGRRFAIVVYSKS +STTSEADRDLAIAEITQTLYDFy +>[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=2 Tax=Sphingobacterium composti Yoo et al. 2007 non Ten et al. 2007 TaxID=415956 RepID=A0A5S5DIG0_9SPHI +---LQPTIQKLLSKKKALVGVSIIHPEHRDTL-NIRGDEQFPMQSVFKFHIATAMLAKVD +EGRFSLHQVIPIKKEDLTPWSPLRDQYPDGVLPLSKIITYMLSQSDNVACDVLLKLLGGP +LAVETYIKSKGIQDIAIRINEETMQNNWDLQFQNWTTPKACTQTLQLFYYNQELSASCHK +FLWDVMKGTETGAKRLKGGLPAGTVVAHKTGFSGTEAVHDAGIIFLPSGQPIFITVFVSH +SQEDTANNEAIIADIAKLVYDYy +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter sp. ZODW24 TaxID=2185142 RepID=UPI000DF82FC0 +---AAARVRSLEGESGGALGAAVLDTGSGEIF-GNRMDERFAHCSSFKLSLAALAMQRAA +NGGDALDTALPITADDITSYSPVTKARVGQTMTIADLAKTTLTKSDNAAANILLRQFGGP +EAMTAFWRSIGDDVSRLDRFETDLNFVPPGEVRDTTTPRAMAKTVQALLYGYALPGKMRQ +TLRSWMIETDTGLNRIRGGIPERWAAGDKTGTGFEGIYVDIAFAEPPSGAPLIITGYLRL +EERVEPNSAAVLAALGAIAA--- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000E6860F7 +----ASEIEHIEQEKNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNSTP +--NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EVFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA +LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYKDKQKPIILAVYTKQ +DQKNAKPDDKIIAAAAEEAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. Leaf299 TaxID=1736328 RepID=UPI0009E9D41C +--AIDAALAADEAEYDARIGLVAVDTEDERTL-EHRADERFRSASSIKALAAGALLARTE +--PADLERVVTW--SDVVDHSPVTGPATATGLPLGEVAEAAVRLSDNTAHNVVLQELGGP +AGLQEALRALGDDVTRVDRIEPELNRVSPE-GLDTGTARSLAADLRALLLGDALDPADRA +QLRDWMSGNATGDALVRAGAPDGWSVLDKSGGAG-GLRNDLAVVERPGAAPIVIAVLTER +RDPSLPYDDALVARAASVALE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=bacterium P1 TaxID=1368078 RepID=A0A0B5ECS4_9BACT +--------------AGNRVDYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEA---------------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI0011C7836E +----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP +--NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA +LLKQVMIENETGNSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ +DQKNAKPDDKVIAVAAEEAIK-- +>[subseq from] UPI0012E0C4A3 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0012E0C4A3 +-dSLKSSIEKYLKDKKAKVGVAVLGIEDNFKL-NVNEKHHYPMQGTYKFHLALAVLDKLD +KENISIDKKLFVKKSELLPWSPLRDKYPDGNLSISEILKATVSRSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD +YLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000267D82B +----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS +--EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKVMEELGGI +KGFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQINDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKDGQPDDKVIADAAEEAI--- +>[subseq from] Beta-lactamase n=1 Tax=Francisella hispaniensis TaxID=622488 RepID=F4BK32_9GAMM +--QITNDIQNIEKKYGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM +TNSKLLNQKIKISKNQIVDYSPITKNHINQKMTIKQLCKASIQ-GDNTATNILIEKLGGL +KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL +MFKQWLIASNTGSSRIAAEIPNEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIIAIFYTQ +SQKNAKPNSKILREVTKILLD-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. JC507 TaxID=1978493 RepID=UPI0010A943E1 +-qELRNKINQIISTKNATVGISLKGIEDKDTL-SINGNKETPMLSVFKFHIALAVLNQVD +KGKLKLNQKFFIKKEDLLPWSPIREEYPQGNLTLDQLIRYTVSHSDNNGCDILLNIIGGT +ETVQKFINQQGIKDFTIKVNEKEMAS-FEKCYINTTTPLATTELLEKFYKGKVLKKESTK +YLYQVMVETSRGLTWMKAGLPTGTELAHRTGISGRAAMNDVGIIKLPNGKHIVLSIYLKN +INEEMTDTEKIIADVTRAVWDYy +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Microvirga TaxID=2617746 RepID=UPI0013766BBA +---------------SGRLGVGLVDLKDGSAW-SWRGDERFPMQSVYKLPIALAILTAAD +DGRLNLDDTIALGREDLSIWSPIAREFKGERYTVRQLAEHALQLSDNTASDALLRLAGGP +GSVTALLHRHGIAGMRVDRSEREMQPAYLADIRDTTTPKAAAHLLAKLARGELLSEPMTR +VFLGILAGTRTGGSRIKAGVPEGSAVAHKTGTAMTGAVNDVGIVTLPGGRQIVVAVFVAG +SDRPPAERERLIASVTRAAIE-- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus lentus TaxID=42858 RepID=A0A4Y9KA80_STALE +----NSAIDKIEKKYDANVGMYALNTQNGEEL-SSNEDKRFAYASTLKAVSSAMLLEKVP +--SNKLDKKIHISKDDIVTYSPVLEKYVDKEITLKKLIEANMLYSDNTANNKIIDELGGY +KEVKKRLVDLGDTLTYPSRKEPDLNLYSPQDKRDTTTPLAFGKTLNKLIIDGNLSKSNKD +FLMNLMFKNKSGDTLIKDGAPSDFKVMDKSGQATYGSRNDVAFIYPKGQKPIILVIFTNK +NNKDAKPNDKIVSEVAEEVLK-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI00057C0C8D +---SASEIKHIEDKNDVTIGVYGMNTENGKVY-KHNADERFAFASTYKAIASGILLNNTS +--QDKLNKKVKINEQDIVAYSPVTEKYIGKTMSLKSLVKASMLQSDNTANNKIIKEIGGI +KGFNKELKNLGDATSKPQRLEPELNNYDPTKIADTTTPKAAATTLNKLLSSSQMDKENQT +LLKQVMVENETGDSLIKAGVPKHYTVGDKSGQATYGTRNDLAFIYTDEHKPIILAIYTKQ +GQKNAKPDDKIIAAAAEKAIE-- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=A0A5R9B5K6_STAXY +----ASEIEHIEQENNVTIGVYGMNTDNSKVY-QHNADERFAFASTYKAIASGILLNNTP +--NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA +LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ +DQKNAKPDDKVIAAAAEEAIK-- +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A3D4JXJ3_9FLAO +-sSLETQINSIIKNKKATVGISVLGFENGFTY-NKNADKKLPMQSVFKFHIAAAVLDYAE +KGKLSLDQKVTLNQSNLHEWSPLREKYPNGAISLSEIIEYTVAKSDNNGCDILLKLLGGT +QVVQKFMNVKGVKNFQIKYNEEAMHKDWNAQYENYSTTNSAVDVLKKFYDGKLLSKKSTD +YLMKVMFSTSTGTNKLIEQLPKDTPVARKTGSSGTGAENEIAIITLPNGKHYAIAVFVSN +STETAEVNCRMISDISKTVWDYf +>[subseq from] CIA family class A extended-spectrum beta-lactamase n=1 Tax=Chryseobacterium sp. ISE14 TaxID=475075 RepID=A0A316XIM9_9FLAO +-sALDQKIKAVIKGKKATVGISVLDFDNNFEY-NKNGDKKLPLLSVFKFHLASAVLDMAD +KGKFSTDQKFLIKKSDLLEWSPLREKYPEGNLSLGEIITYTVAQSDNNTCDFLLRLIGGT +QTVQNFMDSKGAKDLKIQYNEDDMHKDWKNQYGNYSTTNSAVDLLKKFYDGKLLSKKSTD +FLMQIMLGTTTGTNKIVEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVNN +STETEKVNTRMVSDISKIVWDNf +>[subseq from] class A beta-lactamase n=1 Tax=Ponticaulis koreensis TaxID=1123045 RepID=UPI0003B5B0A6 +----HTAIAYMESQNGGRFGVSAVNLATGQTI-THRGDERFAMCSSFKWLLAALVLQQVQ +TGEEDLSRMIEFSEADMVMHAPITEPALGEGLSVEALCRGTVQTSDNPAANLLLRTLDGP +EGFTQILRDNGEMTTRLDRWEPMLNENAPGDPQDTSTPNATVSLMGYYLFGGGLNAEYQT +LLKDWMIGATTGLARLRGGMDAPWIGGDKTGTSSNNQSNDVAFAYRPDADPILITSYLNV +ENPIGAETDELHATIGRQIM--- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Roseovarius gaetbuli TaxID=1356575 RepID=A0A1X6ZRN5_9RHOB +---VAAAIERVATKLAGRIGFAAQEIGGDDVI-AFNGDETFAMASTYKVAIATAIMDRVD +RGELSLDQMVEITPDMMMIDAALSDTFVHPGLSVANLMEIMITESDNTATDTLIGLAGGA +AAVTENLRRLGITDFRVDRTTGEIIGDFEADPRDHATPLAMLQLLLAIDSGTAMSAESRN +FLIDIMSRTRTGAGRLKGLLPRGTPVAHKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS +SESSEADRDRAIAEVARSLYDYf +>[subseq from] Beta-lactamase class A n=2 Tax=Ruegeria marina TaxID=639004 RepID=A0A1G6R4G6_9RHOB +--SVGAAIERVATGLAGRIGFAAQEIGGDDVI-AFNGDETFAMASTYKVAIAAAIMDRVD +RGELSLDQMVEITPDMMMIDAALSDTFVHPGLSVANLMEIMITESDNTATDILMGLAGGP +AAVTENLHRLGITDFRVDRTTGEIIGDFEADLRDHATPLAMLQLLLAIDSGTAMSAESRD +FLIDVMSRTRTGDARLKGLLPRGTPVVHKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS +SETSEADRDRAIAEVARSLFDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=F6KHM3_ECOLX +------------------------------------------------------------ +-EPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTS--- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Cyanobacteria bacterium 13_1_20CM_4_61_6 TaxID=1805100 RepID=A0A1Q8BMQ5_9CYAN +--ELQKRFEVIAKAANGKVGVAVELLETKESI-VLNGQERFPMQSVYKLPIGMAVLQRVD +EGTLKLEQLIQVTPNDFVAHSPIRDAHPLGALSVSNLLQQMVSESDGTACDVLLRLLGGP +ASVGGSLRKLGLTNVVVATTEKEMGQDELVQYRNWAAPEGLTRLLRWLHEGRGLSVPSRE +LLLRFLTETSTGPRRIKGLLPVGTPVAHKTGSSGARATNDAGIVTLPDGRHVAIAVFVSD +SAADEATRDAVIAKISRAAWDYw +>[subseq from] Beta-lactamase n=2 Tax=Francisella novicida TaxID=264 RepID=A0Q6M5_FRATN +--QITNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM +TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL +KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILNKKHRL +MFKQWLIASNTSNNRIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ +SQKNAKPNSKIVREVTKILLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000397D5A4 +----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS +--EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV +KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKDGQLDDKVIADAAEEAI--- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dyadobacter alkalitolerans TaxID=492736 RepID=UPI0003FB1EEE +--DFKSQIESITKQIDGIAGVAIKDLGGNETL-ILNADHKFPMLSSFKFPIAMAVLDQVD +KGKLALDQKYHLTKEDVQLYSPLRDKYPDGNLTIGDLLASMVSLSDNIACDILFKLAGGT +KPVQDYVHSLGVKDIAIVANEEEMGQDWNVQYTNWCKPGAMLQLLNILYKGKNLSKSSHD +FLSKIMIDGPTGMNRIKGQLPKDAVVAHKTGTSGNGAVNDVGVVKMPNGKSFAIVLFMSN +STAELKAIESVMAQVSKAAYDHy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SCQ5_9BACT +-dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDILD +KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD +FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] class A beta-lactamase n=1 Tax=Algoriphagus formosus TaxID=2007308 RepID=UPI000C2858DB +-eALSKKIENLTEKLAGRIGVAAQEIGSKETI-TINGDEQFVMASTYKVAIAAAVLDRVD +RGELRLDQMVDVTLDMMMIGDAALNRFVHPGLSIANLIEVMITESDNTATDISMGLAGGP +AAVTNYLRRIGISDFRVDRSTGEIIGDFEADPRDQATPFAMLQLLLAIDGGKATSSESRD +FLINVMSRTRTGSGRLKGLLPKGTPVANKTGTIG-GVANDVGYITLPDGRRFAIVVFTKS +STTSEADRDRAIAEVTRTLYDFy +>[subseq from] Beta-lactamase n=1 Tax=Francisella uliginis TaxID=573570 RepID=A0A1L4BS25_9GAMM +---ISNEIHKIEKQHGGKVGVYTINRNNWHNF-THSETFYFPICSVYKFLVVGAILKESM +TDSNLLDEKVRISKNQIIGYSPITKKYVGKEITVKELCKASI-LSDNTATNLLIYKLGGL +KKLGAFILSLKDHATKITALEPKINDVNLKNNLNKTTPKIIARDLNKIAFHDVLDKKHRI +LFKKWLKENNTGSNRIAAELPKGWKIGDKTGTCDYGSTNDVAIVWPNDSRAIVISILYTQ +PLKNAKPNDKVIQEVAKILFDNf +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. T16E-39 TaxID=2015076 RepID=A0A220S929_9FLAO +--SLEQKINSIVNGKNATVGVSVLSIENDFNY-NKNGEKKLPMQSVFKFHISSAVLDLVD +KGKLSLDQKVLIKKSDLLDWSPMREKYPAGNLPLSEIIDFTVAQSDNNGCDILLRLIGGT +STVQKFMNSKGVKNFQIKFNEEEMHKGWNVQYENFSTTNSIVDVLKKFYQGKLLSKKSTA +YLMKVMLGTKTGANKLVEQLPKNTPVAHKTGSSGTGAENDMGIVTLPNGKHYAIAVFVSN +STETEAVNCKIISDLSKVVWDDf +>[subseq from] Beta-lactamase n=1 Tax=Providencia sp. TaxID=589 RepID=A0A356D3P4_PROSP +----------IYEKEGWKVGLSILY-SDNSSI-SINGNQRFPLDSTVKSIACANVLAKVD +AQKISLNHSMIVTEENIVTYSPVAKNYINKPFTLEKACKAANEYSDNTAANFAILSGGGP +EGLTAFMRSIGDTVTRSDRYEPELTTNPVDDLRDTTTPNAMSLSIKNILTGEVLSNASKD +QLKEWMMNNKVADNMLRASLPKGWKIADRSGASDYGIRGITSMVWSNDHEPVFISIYVRK +GDTSLEERSEVIRILGSHIFNEy +>[subseq from] Class A beta-lactamase n=1 Tax=Larkinella sp. MA1 TaxID=2607654 RepID=A0A5N1J9J3_9BACT +-qRLNQELDRIAKLAKGKVGLCAVHLESGKQV-SMNLQERFPMASTVKVAIAVELLTKIE +KGDLSLRTMVDLKPSDLHPGSGTLETLFAKPLSVENLLELMMVISDNSATDILLNLVGGV +EPVRARLKALGIQGMSVDRTIVELIAKLEADPRDTSTPEAMVNLLTQIYQAKALKPESRD +LLLAVMERCRGGLARIKGYLPPATVVAHKTGSLNSSATDDVGIITLPGDGHIVIAVFITA +SSQAAAEREQTIAHLSRTVYDYf +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6E4L5_9BACT +--TLEAEIRRITNAAGGEVGVAAWRLDSGPRM-LLNADEAFPMASTFKVAVAGALLGKVD +AGTLSLETVLPVDKSRYVESEVIADTLIHSGLSIHNLLELMLTRSDNTATDVLTSAAGGA +TAVTAWVRAQGITGLRVDRDTAGILRAFDKDPRDSSTPNAMAELLSKIFTGHALSSASTK +EIIETMERCHTGNDRLRARLPATTTVADKTGTLG-GSVNDVGVITLPNGGQVVCAVFIKK +SDLPFADREKVIADIARAVYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas mali TaxID=40682 RepID=UPI000A020036 +-----ADLRALERRAKGRLGAYVLDPVRGVRF-GWRENERFAHCSSFKMSLAAMILAKAD +RREIDPAEVLHWTKADMLGVSPVTEAKIDAGLAVEDLARATLVTSDNTAANVLLRRFGGP +VQLTRFWRSIGDDVSRLDRYEPELNQTPPGTELDTTTPAAMAATTAALIHGKTLSRASRA +KLKAWMREVRTGRDRIRSGFPTGWDSGDKTGTGIKHTYVDLAFGGPAARTPLIVTAYFEP +ARPMDPVATAALAEVGRIAA--- +>[subseq from] Beta-lactamase n=1 Tax=Francisella hispaniensis FSC454 TaxID=1088883 RepID=A0A153JBG9_9GAMM +--QITNDIQNIEKKYGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM +TNSKLLNQKIKISKNQIVDYSPITKNHINQKMTIKQLCKASMQ-GDNTATNILIEKLGGL +KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL +MFKQWLIASNTGSSRIAAEIPNEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIIAIFYTQ +SQKNAKPNSKILREVTKILLD-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A076Q258_ECOLX +------------------------------------------------------------ +---QLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLILVTY--- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacteraceae bacterium TaxID=2026738 RepID=A0A2D6NKY0_9SPHN +-qDLAARISEIETASGGRLGLALHSPDKGLVY-AYRGDERFAMCSTFKLALAALTLDTPG +----LREKRLHFGAXDILSYAPYAKERASSGMSGLEAAHHAVTLSDNTAAXLLLAEVGGP +DGFTRWLRSMGDETTRLDRNEPALNEXAPGDPXDTTTPTAHADLVGTLLWGDRLXXADRA +LLQEWLXXTTTGMNRLRAGLPXEWRAGDKTGTCGQGEVNDIAMFETPDGARYILAAYLDR +ADGSASDAEARLAEAARAIAD-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=unclassified Polaromonas TaxID=2638319 RepID=A0A258TKB8_9BURK +--RFQKEIRQIETDSGGRLGVSVLDTHSGLAY-AYRGDERFPMCSTFKFLAAALVLSRVD +QGQEQLSRRIAVQASDIVPYAPATQPRVGGVMTVAELCDAAVTLSDNAAGNLLLKSFGGP +PGLTAYARSLGDEFTRLDRIEPDLNEATPGDPRDTTTPDAMLKTMQKIVIGPALSPASRE +QITRWLTDNKTGDK---------------------------------------------- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A521NGC4_9CAUL +-------LSGLERANGGRLGFVAHDGGSGRRL-AWRGDERFVYCSTFKMYLAAATFLRVQ +AGQERLDRQIPVAGADMVNHAPVTGPAVGGALSVETLMKGAVEVSDNPAANLLLRALGGL +EPMRAFYRSLGDDSTTVDRFEPGMNRL--DGEKDTIVPLRSVANLKRLLIDTPLSEDHKA +RLLRWMTDTPTGQGRIKAGLPVGWTVAHKTGTGGYGPTNDIGVLYPPAGAPVIVAAYYHA +AAGPADRHDAVIAEATRLAL--- +>[subseq from] VEB-PER_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059XER2_9BACT +-aKLKSEIETISKDAKGIVGVGVMDLKTRETL-LMNQEHKFPMQSTFKFPLAIAVLDLVD +KGKYKINQKIHVKSAGLDPHSPMRDKRPNQDITIGELLSYSVSESDNNACDILFELAGGT +KKVNEYIHSLGVKDIAIVATEKEMKAGWDVQYTNYARPSAYLQLLQIAYERRKLSKASHD +YLWKMMVEGPTGLKRIKGLLPKGTEVAHKTGTSGTNATNDAGIIRLPNGKDIAVVVFVSD +AAANMDTRELVIARIAKAVWDYy +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000D1CFF96 +----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS +--EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKVMEELGGV +KGFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQINDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKDGQPDDKVIADAAEEAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus sp. KY49P TaxID=2664181 RepID=UPI0012998B8E +---SASELKHIEQENDVTIGVYGMNTDNGKVY-KHNSDERFAFASTYKAIASGILLNNVP +--NSKLNKKIKINERDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIIDEIGGL +EGFNNELQGLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLASNQMDKDNQA +LLKQVMIENETGDSLIKAGVPKKYIVGDKSGQGTYGTRNDLAFIYTDHRKPIILAVYTKQ +DQKNAKPDDKIIAAAAEEAIK-- +>[subseq from] Beta-lactamase (Fragment) n=6 Tax=Bacteria TaxID=2 RepID=A0A411NN22_ECOLX +------------------------------------------------------------ +---------------DLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDV------------ +>[subseq from] Beta-lactamase n=1 Tax=Pelomonas sp. TaxID=1909303 RepID=A0A5C7VJN7_9BURK +--DLAPALAALEARAGGRLGFAALDTGSGRLL-GHRLDQRFGMCSTFKLPLAALTLRAVE +QHEL-QDDWVALGEISPRDFAPATRAQLPAGMKLLALAEAVQTTSDNIAANLLLARLGGP +AGFTQRLRALGDPVTRLDRVEPLMNRVLPGDERDTTTPAAMAQTVAAIFTGEWLQPAGRA +TLRRWAEATRTGVRRLRAGLPADWPAGDKTGTGLAARTNDVAIMWPPGRAPWVMAAYFEG +PGSDPAADEAVLAEAARLAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI000158B2FA +--QVTNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM +TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL +KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL +MFKQWLIASNTSNNRIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ +SQKNAKPNSKIVREVTKILLN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WV98_9BACT +---LERAIKRLAESSGGIVGVSAIHIESGRRV-SMNGGTRFPMASVYKLPIALQLLNKVD +RGELRLQDSITLSAHDFRPHSPIVEFANNKPLTLERLFELMLGESDNSASDALLRLAGGP +AAVTNRMQALGITGINVSRPEGELILAYADDPRDTSTPDAMADLLVRVHRRDVLEPASME +RLLQIMTATQTGPARLKGLLPTGTIVAHKTGTMG-GTTADVGIVTLPDGGHMAIAVFVKA +STKEVPERERVIAEIARTIYDY- +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2U8T2R2_ECOLX +---------------------ALINTADNSQI-LYRADERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPITEKHVNGTMTLAELSAAALQYTDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPASW------------------------------------ +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Fimbriimonas ginsengisoli Gsoil 348 TaxID=661478 RepID=A0A068NK12_9BACT +-----GRVQALEAGLHGSIGVAVTDLRTGESW-AYHGDSRFPMQSVFKLPLGIAVLDAVD +RREHSLDTRIMVGWQHLSVMSVINDRFSGHAYSVAELLELAVGVSDNTAADLLLSMMGGP +QKVTARLKRMGINGIRVDRFERQLQVKYLADPRDTATPNGMVDLLAGLQRGRFLSPASRE +RLLRIMTASTTGPNRLKAGLPKGSTLAHKTGTGRCGAINDVGIATLPGGRKLAIAVFLSG +TSGTKTTRERIIANVARAVTD-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chitinophaga sp. SYP-B3965 TaxID=2663120 RepID=UPI0012998278 +--RLRLQIAQIAATIDGQVGVSIRNLDTRDTV-TFNDTTNYAMHSVFKFPIAMALLHQVD +QGRLQLEQKIYIDKKWMVPHSPLRDSFPAGNVTLSHLLSLMVSQSDNIACDVLIDLAGGE +GAIDEYIHSLGVKDIAIAASEAKMASSWDVQFTNWSTPTAIVDLLEILNKGTALSKTTNA +FLWKIMTETSTGPHRIKGLLPANVVVAHKTGTSGYAATNDAGIIFLPNGQKLAIVVFVSM +SKADEATREGVIAKVAKAAYD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Cytophagaceae bacterium TaxID=2026729 RepID=A0A4Q5R1H2_9BACT +---LQTELERVVAGFAGTVGVVVRGVEGGDSA-QLQAQAHLPMQSVYKFPLALAVLHAVD +EGRLQLDQKIWLRPADLLPWSPLRERYPQGNVSLREVLRYTVAESDNNGCDMLFRLLGGP +AAVQAYMHRLGVADLRIAATEEEMHRQEDVQFKNWATPFAMSELLVNFSRGHYLSAASHA +CLWQLLTTGPTGLQRLRAGVPTGTEVAHKTGTSGTNATNDAGLLTLPNGRHVAVVVFITN +STASEADRESLIAAVSRTAWQHf +>[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium saccharophilum TaxID=29534 RepID=A0A1M6ZPK6_9FLAO +-sDLRQQLNQIIATKNATVGISIKSIEDKDTI-SINGNLKAPMMSVFKFHIALTVLSQVD +EGKLSLNQKIFIKKKELHEWSPMREEYPNGNLTLDQVLRYTVSHSDNNGCDILIDLVGGT +KVVQKFIDKQGIKDFVIKVNEKQMES-WKNLYVNTTTPLATTELLEKFYKGEVLKESTTQ +YLYQIMVETSRGLTWMKAGLPAGTELAHRTGTSGTNAMNDIGIVKLPNGKHFILSVYLKE +ITEKQEDTEKVIADIARATWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI00085315A9 +----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS +--EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV +KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKDGQPDDKVIAYAAEEAI--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A248XBE9_ECOLX +------------------------------------------MCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMSKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNHIA------------------ +----------------------- +>[subseq from] Class A beta-lactamase n=2 Tax=Luteimonas aestuarii TaxID=453837 RepID=A0A4R5TSY2_9GAMM +--ALQREAERLAGQLRGSVGAAAIHVESGRSV-FVDGDRAFPMASTMKLPVAVHILKQVD +EGTLSLTQQVLLAPGDVYPMGGPMDLHLTPGITVRDLLHMMITVSDNNATDLLLRLGGGT +AAVDARMRALGIDGIRVDRYIWELLAAYNADPRDTATARAMATLLARLWRGELLSADSTQ +LLQAIMQATRTGGDRLRGALPPHTPVAHKTGTVGD-MVNDVGVITLPDGRGHVVVVAFVQ +SDAPAATRAGTIAQLARAAHDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A0K2DRT4_KLEPN +-----------------------------------------AMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGEALGDSQRA +QLVTRMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDI------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Francisella tularensis subsp. novicida PA10-7858 TaxID=1386968 RepID=A0A1I9Y9W4_FRANO +--QITNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM +TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL +KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL +IFKQWLIASNTSNNRIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ +SQKNAKPNSKIVREVTKILLN-- +>[subseq from] Beta-lactamase n=2 Tax=Actinosynnema TaxID=40566 RepID=C6WI80_ACTMD +------ELAELEERHGARLGVRVVDTGSGAAV-GHRADERFPVCSLISAYAAGALLVAND +WADGFFQQVITYERAELIGNSPVTGSRVDGGMTVAELCDAAIAHDDSTALNELLSLVGGP +EAITAFAFALGDEQTRLDRWEPDLNAAEPGDERDTSTPGALAAGYRNLVLGTALEARERA +ELRGWLEGGGT---VLRSVVPRGWVVGGKPGAAEYGTRCDAAIAWPPDRDPLVVVLMSTR +PERDARADGTLLGDAARVAL--- +>[subseq from] Beta-lactamase class A n=1 Tax=uncultured bacterium TaxID=77133 RepID=E4WMD6_9BACT +------ELDSVPQVSSGRLGVAILDFQTSKTY-HINGKDRFPMQSVFKAMSAVVVMREVD +EGKLTLDQEIPVGPDDISVWSPIAEEFKGTTYTVRELLEKSVGMSDNTAADVLMELTGGP +QAVTQLLKDAGIEGVRVDRYERQFQAVAGKDERDTATPLGAVDFLVKLQEGKLLSAESTR +VLLQIMTDVKTGAGRLKAGLPEGSKLAHKTGTGGNTATNDIGIATLPDGRKFAVAVFLTG +SKESEEKRDAIHADVVRQFVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. 7 TaxID=2035214 RepID=A0A497V3G5_9FLAO +-kDLRNKINHIISTKKAEVGISLKGIENKDTL-SINGKKETPMMSVFKFHIALAVLNRVD +QGKLKLNQKFFIKKEDLLPWSPIREDYPQGNLTLDQLIRYTVSHSDNNGCDILLNIIGGT +ETVQKFINQQGIKDFTIKVNEKEMAS-FEKCYLNTTTPLATTELLEKFYKGKVLKKESTK +YLYQVMVETSRGLTWMKAGLPTGTELAHRTGISGRAAMNDVGIIKLPNGKHIVLSIYLKN +INEEMADTEKIIADITRTVWDYy +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=A0A418IL74_STAXY +---SASELKHIEQENDVTIGVYGMNTDNGKVY-KHNSDERFAFASTYKAIASGVLLNNVP +--NGKLNKKIKINERDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIIHEIGGI +EGFNNELQGLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLASNQMDKDNQA +LLKQVMIENETGDSLIKAGVPKQYIVGDKSGQGTYGTRNDLAFIYTDHRKPIILAVYTKQ +AQKNAKPDDKIIAAAAEEAIK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium oleae TaxID=491207 RepID=A0A1I4VLE3_9FLAO +---LEQKINSITEGKKATVGVSVLGFENNFKY-SKNGDQPLPTLSVFKFHIACTVLDLVD +QGKLSLDQKLFFKKEDMLEWSPIREKYPDANLPLSEVLDYTVALSDNNGCDVLLRLIGGP +QTVQKFMDSKGVKGFQIKHNEAEMHKSWKALYENYSTPNSSVQVLKKFYDGKLLSKKSTG +YLMQIMIGTKTGTNKIIEQLPKNTPVAHKTGSSGKNAENDMGIITLPNGKHYAITVFVND +SMETDAVNCKMVSDISKAVWDDf +>[subseq from] class A beta-lactamase n=1 Tax=Scytonema sp. UIC 10036 TaxID=2304196 RepID=UPI0012DAF683 +-------------AARGNVGIGVLDLKTGKSW-FRNGKQRFPMQSVYKVPIAIAVLKRVD +EGKLALNQSVTVTRQEFAPWSPMTQEFKGNSFTVQNLLERSVGISDNTAADVLVRLVGGT +EQVNAILGKLKIRDVRVDRLERQLQSKYLADPRDTATPEGIVDLLVKLQSNQLLSQKSTA +LLLKIMTDSPTGAKRLKAGLPHNWSIAHKTGTGPGTATNDVGIVSSPNGKRVAIAVFVAG +SKAPIEAREKVMSDVASVVVK-- +>[subseq from] Beta-lactamase n=1 Tax=Chthoniobacterales bacterium TaxID=2201154 RepID=A0A2W5ZLY3_9BACT +---AQSEIERIATTAAGQVGVAAWRLDTGPRL-LFNADQSFPMASTFKVAVAGALLAKID +AGKLKLDQMLTVDPAQYIESEMIATTHPGVSLSVHNLLELLLTYSDNTAADVLTAAAGGP +EAVTAWVRSQDVNGLRVDRDTGGILRAFDNDPRDTSTPTAMAELLTKLFAGHALSPAGTK +TLVETMERCHTGDNRLRARLPAPTTVADKTGTIG-GSVNDVGLITLPNGGQVVIAVFIKK +SDLPFAAREKVIADIARATYDFf +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia pneumoniae TaxID=228601 RepID=UPI000594C8FC +-----PSFTEMETNHAARLGVYAIDTASGRTV-GHRDGERFPMASTFKGLACGALLRDHP +LSTGYFDQVIHYSRADLVANSPVTEKHVDTGMTVAELCDATITVSDNTAGNQVLKLLGGP +AGFTAFLRSIGDNTSRLDRWETELNTAIPGDERDTTTPAALAADYRALVLGDVLGEPERE +RLKSWLIANTTGDKRIRAG----------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Microbacterium sp. CGR2 TaxID=1805820 RepID=A0A3B0B8X3_9MICO +haDTEQELVALEQEYNATIGVVAVNTGTGESV-SYGENRRFGFASTIKAFAAAEFLRTVQ +--GPDRDELVHWTADEADANAPVTSQHVEEGLTYAQLAEAAVRFSDNAALNLVFDRIGGP +QALDDALTDLGDTTTEVVNNEPTLNTIEPDSTEDTTTAAAFTASFEAYLDGSTLTAADTA +LLLDWMSDNRTGDPLIRAGAPAGWVVADKSGGAGP-IRNDIAMITPPGEAPILLTVLTSR +NDPDAAFDNTLVARTASTML--- +>[subseq from] class A beta-lactamase n=1 Tax=Acetobacter farinalis TaxID=1260984 RepID=UPI00140DCCC0 +-------LDAIENRYGGRLGVFAQDTASGRTL-MHRPDERFTMCSTFKGLLAAQVLWKIE +RGQEQFSRLIHYTARDLKDACPVTAANVQRGLTVEALCQAMVEMSDNLAAILLMRSIGGP +SSLTAFVRSLGDTVTRSDRYEPFSNTY--DGLLDTTTPRAIAKTAGTILLGSTLQQDTRD +LLTRWMINTKPGLQRLRASFPGDWVSADRPGTSGPDETNDYAVVWPPGRKAILMAAYYHA +PHISMDGREAVLRHVGSVI---- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000D1D71A7 +---SASELKHIEQENDVTIGVYGMNTDNGKVY-KHNSDERFAFASTYKAIASGVLLNNVP +--NGKLNKKIKINERDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIIHEIGGI +EGFNNELQGLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLASNQMDKDNQA +LLKQVMIENETGDSLIKAGVPKQYIVGDKSGQGTYGTRNDLAFIYTDHRKPIILAVYTKQ +AQKNAKPDDKIIAAAAEEAIK-- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=A0A2T4QBZ7_9STAP +----ANEFDQLEKENSTTVGVYGINTESGEEI-NHHSDERFGYASTFKAIASGVLLNNYT +--EKELNKKIQIQQKDIVAYSPVTEKYVGKQMSLKALIEAAMLKSDNTANNYIIGEIGGI +SSFKADLQQLGDHVSDPQRLEPKLNDYEPTSTADTTTPRAAAHTLNELLTSHQMNTKNLK +LLKRVMIENETGDQLIKAGVPKHYLVGDKSGQGTYATRNDIAFIYPKDDKPIILAVYTKK +DDKEGTPDDKVIAKAAQIAIK-- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=A0A4Y9KQC1_STASA +---SASELKHIEQENDVTIGVYGMNTDNGKVY-KHNSDERFAFASTYKAIASGVLLNNVP +--NGKLNKKIKINERDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIIHEIGGI +EGFNNELQGLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLASNQMDKDNQA +LLKQVMIENETGDSLIKAGVPKQYIVGDKSGQGAYGTRNDLAFIYTDHRKPIILAVYTKQ +AQKNAKPDDKIIAAAAEEAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter mangrovi TaxID=1982042 RepID=UPI000BA22C79 +---IDAKLHLIEVANGGALGAALLDPLSGDVI-GNRADERFALCSTFKASLVALVLDLGI +AGKLDLGEVVYWTQADLLSYAPFAKQRLANGATITELAGAAQILSDNTAANLLLQRVGGP +EGLTAFWRSLGDEVSRLDDIEGALNHVLPGSERNTTTPRAMATTLAKILYSGAIAREASD +QLKAWMRETQTGAKKVRAGLPQGWDAGDKTGNSGYGVSADIGFAVPPNGAPIIFAAYHRA +AAAPSANADAALAQVGEAI---- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6E5T9_9BACT +--TLEAEIRRIANAAGGEVGVAAWRLDSGPRM-LLNADEAFPMASTFKVAVAGALLGKVD +AGTLSLGTVLPVDKSRYVESEVIADAFIHSGLSIHNLLEVMLSRSDNTATDVLTSAAGGP +GAVTAWVRAQGITGLRVDRDTAGIVRAFDKDPRDSSTPNAMAELLTKIFTGHALSSASTK +EIIGTMERCHTGNDRLRARLPSTTTVADKTGTLG-GSVNDVGVITLPNGGQIVCAVFIKK +SDLPFADREKVIADIARAVYDYf +>[subseq from] Beta-lactamase n=1 Tax=Cytophagaceae bacterium BCCC1 TaxID=2015573 RepID=A0A257IYG5_9BACT +--DLNKQFSEIIGDKKVKVGICVYDFKTKNFY-SINLKEHFPMQSVFKFHIALAVLDLVD +KGKLSLSQKVYISKERMEAYSPLRDKYPNGNLTIAEILKPTVSESDNVGCEVLLDLIGGP +KTVDDYLKKIGMKDVQVKHNETIMQASWEPQFENYSSPNSAVELLKALHNGKILSPKSRA +YVQKMLLETSTGPNRLKGLLPKGTVVAHKTGTSGTNAVNDIGIITLPNGNQFAIAVFVSN +SKEKIETNEKIIAEIAKATYDY- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WQ24_9BACT +-dELQKQIERIAASAKGRVGVAAEVLETGESI-SLNPQDHFPMQSVYKLPIGMAVLAHVD +TQKLSLDQRVRVEKSDYVRHSPIRDKNPKGVLTFKELLRFAVSESDGTASDVLLKLA-GV +EAVAKYLNELGISEIVVANSEKEIGKDWETQYRNWASPQGALQLLRGLHEKRGLTEQSQQ +LLLKLMTETPTGPKRLKGLLPQTVVVAHKTGTSGSAATNDIGLITLPSGRHLAIAVFVSD +SPADLPTRERVIAEIAKAIYDAy +>[subseq from] Beta-lactamase class A n=1 Tax=Pedobacter sp. OK701 TaxID=2135718 RepID=A0A4R7EPX5_9SPHI +---FRNKLNEIVKAHKATIGYSLLDLQNGDTI-TVNGAKHLPMQSVYKFHLALTVLHQVD +QGKLQLDQKILVRKQDLLPWSPLRDKYPAGNIPLSELLSFTVSQSDNNGCDILFRLMGGP +AKVQQYIHSLGVSEVAIAATEEQMHRDDQMQFTNWSTARSATQLLGLFYAKPILSKSSAD +FLWKVMSETTTGPNKIKGLLPPATEVAHKTGYSGTAATNDIGIVTLPNGKHFAIAVFVSM +TTEDEKTTDRIIAELSKASWDE- +>[subseq from] Class A beta-lactamase n=1 Tax=Hymenobacter sp. MA3 TaxID=2607656 RepID=A0A5N1IT66_9BACT +--TLAQQFAALAKPAGGRVGAAATLVETGETV-TLAGAEHFPMQSVFKLPIAMLVIHQVE +QGKLRWTQRVRLAPADMRKHSPLREQHPQGTLTLQELTRYMVSESDNSACDKLLSLIGGP +AAVTQYLKNLGLSNVLVATTEGEMAEDELAQYRSWASPAGMAGLLVAVQKGKSMSAANHA +LLLRYLTNTTRGQARLKGLLPAGTMVAHKTGGSGTRATNDVGIITLPNQQHLAVAVFVTD +SRATEAVREGVIARIAQAAYLHw +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Enterobacterales TaxID=91347 RepID=A0A076V5H0_9GAMM +------------------------------------------------------------ +-EPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILV----- +----------------------- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. c4a TaxID=1573582 RepID=UPI00135C27B8 +---LDQKINAVIKGKKATVGVSVLDFETPFKY-SKNGDKKLPLLSVFKFHLACAVLDQAD +KGKLSIDQKILLKKSDLLEWSPLREKYPNGDLSLGEIITYTVAQSDNNTCDFLLRMIGGP +QTVQRYMDSKGVKDLQIKYTEDDMHKDWKTQYGNESSTNSTVEVLKKFYDGKLLSKKSTD +LLMQIMLGTTTGTNKIVEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVSN +STETEKVNIRMVSDISKIVWDNf +>[subseq from] class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI000158AFF2 +--QVTNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM +TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL +KNLNKFVLSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL +MFKQWLIASNTSNNRIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ +SQKNAKPNSKIVREVTKILLN-- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium nematophagum TaxID=2305228 RepID=A0A3M7L7C7_9FLAO +---LDKRINSIIKDKKATIGISVLGFENGFKY-HKNGEKRFPMQSVFKFHIAAAVLDAVD +QGKLSLHQKILLKKSDLLEWSPLRDKYINGNIPLSEIIDYTVALSDNNGCDILLRLIGGT +QTVQKFMDSKGIKGFQIKYNEEAMHKDWKYQYENYSTPNSATQLLKKFYDGKLLSKESTE +YLMKVMLGTKTGLNKMIEQLPKNTPVARKTGASGTGAENEIGIVTLPNGNHYSITLFVSN +STETDSVNCKIISDISKVIWDYf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KHC7_9BACT +-----SLFQELEEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS +--IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFTLLDGP +NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLAFNLKEYVTGDILSDDKKE +IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRNDIANCNTP------------- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Cellvibrio mixtus TaxID=39650 RepID=A0A266Q8C2_9GAMM +----AERLQKLEVG-QARLGVCFLDTVTGEVS-GNRIEERFAICSSFKLAMVAVCLREAD +NGRLNLEEILPYSEADLLPWAPVTREHLAKGLSIATLAQAAQEKSDGVAANLLVKRLGGP +KAVTAKFREMGDTVTRLDRYEPDLGLVLSADTRDTTSPLAYAQLVSRILTGSILRPDSRE +RLLGWARNTTTGARRLRAGLPSEWRTGNKTGTGRTNKCNDVAITFPPGKNPIIIAAYFDS +GEKIEARHEAVLAEVGKIAAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Asaia bogorensis TaxID=91915 RepID=UPI000EFC478A +hqALSDIATRYEKISGGRLGVHIFCPENGTAL-SWRGEERFRMCSSFKASLAACVLARCD +RDEDDLTRRIAFRESDFKEWAPVAARNRDAGLSLAALCAGAVTMSDNICANMLLRHIGGP +AALTRFWRDSGDEITRLDAYEPELNRPSANPDDNTTSPVAMARTLHRLIHGTLLHPSSAA +LLRSWMINCTTGTQRLRAGLPAHWVVGDKTGNNGKDIAADIAFASPDAGKSVIIATYTAG +GTPDETQFRRVFHDIGALA---- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=unclassified Escherichia TaxID=2608889 RepID=A0A076V5H4_9ESCH +------------------------------------------------------------ +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLILV----- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000853B5C2 +----ANEFDKIEKDNNTTVGVYGINTENGKKV-HHNANERFAFASTFKAIASGVLLNNYS +--EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV +KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKDGQPDDKVIAYAGEEAI--- +>[subseq from] Beta-lactamase n=1 Tax=Aquimarina spongiae TaxID=570521 RepID=A0A1M6DUK0_9FLAO +--TLRHKLGDIIQSKNVVVGVAIHGMDDKDTL-SINGHKHFPMQSVFKFPIALRVLSEID +KGNFSLEQKINIKKSELLPWSPIREKYPEGALTLAEIMKYTVAVSDNVGCDVLLRLMGGP +EAIENHFSKLGFKDFEVKINEETMQNNWDQQFLNWTTPQEANRILKAFYENSLLTKESHQ +FVWDVMKGTKTGKNRLKGQLPKETVVAHKTGWSGTAAVNDIGLVFLPNGKYFAISVFVTE +SSENFETNEKIIADITKVAWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Haloactinobacterium sp. HY044 TaxID=2675753 RepID=UPI0013D5BCDF +------ALVRLEEESGVRIGAVGI--SAGARV-DHRAEEAFPMCSLFKVLAVAALLRERA +YDDAYWAEPIPFGPADLVEDSPVTSATTTWAMSPTALADAALRFSDNTAGNLLLAELGGP +EAITTFAADLGAASTRLDRWEPELNEATPGDLRDTSTPSDIALLYRALLLEDRVGALAGA +RLRDWMLRNTTSAARIRAGLNGDVELADKTGAGRYGVVNDAGVLWAGGSDPITLVILTRT +DDPAAVNDNEVVADATRIIMS-- +>[subseq from] Serine hydrolase n=1 Tax=Xanthomonadaceae bacterium TaxID=1926873 RepID=A0A3C0JEG6_9GAMM +---LQAELDRITAPFDGQIGVYVLDLDSGRTA-SVNPQIGFPMASTVKVPVAVHILSLVD +EGKLDLQRPVVLKAEDIYPGGPIDTHLTPGSITVHDLLHMMLTVSDNNATDILIKLGGGT +AAVAARLHALGIEGIRVDRYIWEMLAAYDADPRDTSTPAGMAALLSRVWQGKVLKPATTA +VLESIMLDCRTGRQRLKGMLPDATPVAHKTGSVDD-VANDVGVITLPSGRGRVVIAVFEK +SEQDDAAKDRMMAQVARAAHDYf +>[subseq from] Serine hydrolase n=1 Tax=Vibrio breoganii TaxID=553239 RepID=A0A193KIS0_9VIBR +-----KQVEAITAPLVGRVGFAAQLIGSDKII-AYNGDMTFPMASTYKVPAAVTLLKRVE +AGEVKLDDMVELHLDDMVADNVIAENFVHPGLSVANLIEPMITMSDNTAADFVISLAGGP +KAITDAMRKLGIKDMRIDRNIKDLFRKYEADPRDQSTPFAMLDLLMKIDSATAISEDSRD +FLIASMSRTRTGAGRIKGLLPRGTPVAHKTGTAT-GVANDVGYVTLPDGRRFAIAIYTAS +SDTPMADRDRAVAEVARTLYDYf +>[subseq from] Beta-lactamase n=4 Tax=Staphylococcus TaxID=1279 RepID=F4NA56_STAAU +-nSTNNDIEKIEKKYGANVGMYALNTQNGKEL-SFNENKRFAYASTLKTISSAMLLEQTP +--YNKLDKKIHINKDDIVPYSPVLEKYIGKEITLKKLIEATMLFSDNTANNKIIDELGGY +GQVKTKLIDLGDTTTHPSRKEPDLNFYSPKDKRDTSTPLAYGKTLKKLIADGDLSKANKD +FLLNLMFKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVAFVYPDGQKPIILVIFTNK +DRKDGKPNDKIVSEVAEIVLK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=V5T9H5_ECOLX +------------------------------------------MCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKRVNGTMSLAELSAAALQYSGNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIA------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Pseudarcicella hirudinis TaxID=1079859 RepID=A0A1I5TJU2_9BACT +-eSFEEQVKNLAKNIKGTVGVTVMKVEEKQHF-SWNGDKHFPMQSVFKFPIAMAVLHEID +SGNCSLDKMIHVAKEDMYKYSPLRDKYPEGNVSIRDLLVYMVSLSDNNACDILLEKVVSV +SKTETFLRKLGIKGIQIKASEKEMGKDWNVQYTNWTQPVEMGRLLEIVFREKALSKSSNT +FLLKIMTETPTGLKRIKGLLPEGTSLAHKTGTSSTAAVNDVGIVTLPNGKHLIICIFIMN +ANERAEGIEPTIAAIAKAAFD-- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2G4FUC3_9BACT +---LSAEIDRVAPISGGILGIGIHHLETGREL-YVRGDDRFPMASSFKVPVAVQLLTLVD +QGKLRLDSMVTLKPSDLHPGSGTLTSLFDDPLSVRNLLELMLLISDNSATDILLRLAGGG +DPVNARLRALGVSGISVDRPTVALIAAFYRDPRDTATPKGMAALLRKIWRGEALSSKSTA +LLIDIMYRCQTGQARIKGLLPPDVRVAHKTGTLGLGVAADIGVIELPGGGHLIVTAFVKQ +STKDGPEQERAIAQAARAAYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Porphyrobacter colymbi TaxID=1161202 RepID=UPI000A39CBFE +--RLAAELRIIEAASGGTLGVELYNTATGASV-GINQDKRFGHASSFKFSLAALLLQRDA +AGTIDADQKVTWTEADMLSHAPFTRERIGTGATLRELSRATQTTSDNPAANILLRYLGGP +AGLTAFWRSLGDEVSRVDRFEPEMNLVPATEFRDTTTPAAMARTVAKIVYGDVLPEKERA +ELKQWMIETETGLKRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKGPPITFACYLRA +RQTELAAPQAALAQVGRII---- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=UPI000D1F9FD0 +-----KSIKDLEATYDTTIGVYGINTQDGKQI-EHRANERFAFASTYKAIASGILLNQLS +--PQDLNQKVTINKSDIVTYSPVTEKYIGKTMTLRQLIEASMLKSDNTANNKVIQAIGGV +NAFKSELRQLGDCVSEPQRLEPDLNNYDPKKIADTTTPRAAARTLNYILTHSNMHKGNLQ +FLKELMIENETGDSLIKAGAAKDDIVGDKSGQGTYATRNDLAFIYPKGQKPIILAIYTKQ +SDKNAKANDEVIAKTAEIAIKY- +>[subseq from] class A beta-lactamase n=1 Tax=Gordonia sp. i37 TaxID=1961707 RepID=UPI0009ADA55A +--SIDAQIRHIATANDVTTGVWAQDLRTGRVIaAVNCEQRYPVLSMSKVYLAAAVLDAAR +HGLLRMDSRVPVHADHIVANSPITSTYAGRTLNYSEIAKAALQYSDNTAANLMFAAIGGP +LGVTAYARTAGDGATVMVREETELNTAFPGDSRDTTTPRAWAAGLRSTMSGARLDPRDRV +TLLGWMRGTHTSDKRFRADLPAGWSTADKTGTGDYGTANDAGVLYGPDGALILLVIQTRS +ATSKATARDSVIGQTAALVTA-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium antarcticum TaxID=266748 RepID=A0A3S4WPJ3_9FLAO +-qSLKKEINQIIKGKSATVGVSVLDFENNQSI-DINGNKKLPMLSVFKFHIALAVLDLID +QGKLSVDQNIYIKKEELLEWSPIRENYPEGNMTLGELIKYTVAQSDNNGCDILLRLIGGT +ETVQKFINSKSIKDFKIIYNEEKMHEGHQFHYGNWTTTNAANILLKKFYDGKIVSKSSTD +FLMKTMLETNTGANKIVAQLPKGTWVAHKTGSSGKDAENDIGIITLLNGKQYALSVFVSD +SMENETTNTKMVADISKLVFDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. LM2 TaxID=2593646 RepID=UPI00117C9E39 +---LDQKISTIIKGKKATVGVAVLSFEDNFRY-NKNANKKLPMLSVFKFHIAAAVLDWVD +QGKLSLDQKIFITKKDLLEWSPIREKFPNGNMSLDEMIYYTVAWSDNNGCDILLRLIGGT +ETVQKLMDSKGVKNFRIKNNEEQMHKGIQYLYENYTTPNSLAQLYKDFYQGKILSEKSTE +YLYNIMLNTETGTNKLKEQLPKK-VIAHKTGSSGKTAENDSGIVTLPNGNHYSIVVFISD +STESEVVNCKMVSDISKTVWDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. RU33C TaxID=1907398 RepID=A0A1N6PIF7_9FLAO +-qELRNKINQIISTKNATAGISLKGIEDKDTL-SINGNKETPMLSVFKFHIALAVLNQVD +KGKLKLNQKFFIKKEDLLPWSPIREEYPQGNLTLDQLIRYTVSHSDNNGCDILLNIIGGT +KTVQKFINQQGIKDFTIKVNEKEMAS-FEKCYLNTTTPLATTELLEKFYKGKVLKKESTK +YLYQVMVETSRGLTWMKAGLPTGTELAHRTGISGRAAMNDVGIIKLPNGKHIVLSIYLKN +INEEMTDTEKIIADVTRAVWDYy +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. BMG51109 TaxID=1056816 RepID=UPI0004648033 +---AEDHFAALERKYDARLGVYAMATGTSVAI-AYHADDPFAFASTYQTLAAAAVLRQRP +--LSYLDTVVRYVPEDVNSFSPVTREHIETGLTIRELCDAAVRFGDGTAAGLLMRDIGGP +EQLTAYLRSLGDTVSRIDLYEPELGGVAPGDPRGATTPRALAADYQQIVLRAALAPQQEV +LLKDWLEHGTTGADTIRAGVPAGWTVAGQAGLGGYGRACDAAVVRPPGGAPLVLTVLTDR +PGPADEPRPAMIADAARYVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000D1D203E +----ASEIEHIEQEKNVTIGVYGMNTDNGKVY-QHNADARFAFASTYKAIASGILFNNTP +--NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA +LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYKDKQKPIILAVYTKQ +DQKNAKPDDKIIAAAAEEAIK-- +>[subseq from] Beta-lactamase class A n=2 Tax=Mucilaginibacter gracilis TaxID=423350 RepID=A0A495J4C7_9SPHI +---LRAQIKEIAKDAKGAVGFAMLGIENRDTL-SYNGQLHLPMQSVMKFPIAITVLHQVD +EGMLTLDQLIPIDKSDLPEYSPLRDKFPEGNIAIRELLSYMVSLSDNDACDILLKTLGGT +AVVDAYMHSFGIKQIAIKASEFQMAQAWDVQFTNWTMPKEMIRLLDIATKPNFLSKTSHD +YLWKIMEATITGPNQIKGLLPAGTIVAHKTGRSGTNATNDVGIITLPNGKHLAVAVFVTN +SAVDLPARESVIARIAKAAYDY- +>[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas sp. NEAU-YY56 TaxID=2483352 RepID=UPI0013157B00 +----AAALADLEAETGYRVGVHAVDTVTGDVV-NHRADERFGYASTIKALALGVALRGAD +--PSVLDRTLPVTAEDVAGYTPVTADRVGSSMTLADLGAAAVSLSDNGALNVVLRDLGGP +AALRAVLVDLGDTTTQVDAVEPDLNRFTPGEPARTSTPRALADGLAVFALGDELDPAVRE +VYVGWLTGSTTGDATIRAGAPEGWLVGGKTGTAGYGSRNDVAVAWPPEGAPVVVAVLTDH +PDPAAAPDDTVVARAAAIVLGAy +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga niabensis TaxID=536979 RepID=A0A1N6J9Z2_9BACT +-sKLRQQIAGIAATIDGQVGVSIRNLDTRDTV-TFNDSTHYVMHSVFKFHIAMTILHQVD +QGKLQLEQKIYIDKKWMVPWSPLRDSFPAGNVPLSKLLSLMVSLSDNIACDVLIDLAGGE +GAIDEYIHSLGVKDIAIKASEAKMASSWDVQFTNWSTPTAMIELLEILNKGTALSATTNA +FLWKIMKETSTGPNRLKGLLPKDVVVAHKTGTSGHAATNDVGIIFLPNGQKLAIAVFVLM +SKADDAAREGVIAKIAKAAYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Gordonia sp. i37 TaxID=1961707 RepID=A0A1V4PU69_9ACTN +--SIDAQIRHIATANDVTTGVWAQDLRTGRVIaAVNCEQRYPVLSMSKVYLAAAVLDAAR +HGLLRMDSRVPVHADHIVANSPITSTYAGRTLNYSEIAKAALQYSDNTAANLMFAAIGGP +LGVTAYARTAGDGATVMVREETELNTAFPGDSRDTTTPRAWAAGLRSTMSGARLDPRDRV +TLLGWMRGTHTSDKRFRADLPAGWSTADKTGTGDYGTANDAGVLYGPDGALILLVIQTRS +ATSKATARDSVIGQTAALVTA-- +>[subseq from] Beta-lactamase n=1 Tax=Oxalobacter formigenes OXCC13 TaxID=556269 RepID=C3X8Y5_OXAFO +---LQENIDAIVKDKPAQIGVVIEGFDPHQHA-GFNENTRFPMQSVFKFPVALAVLDQVD +KGKINLDETLLLKPSDLLPHSPLREKYPEANVSIGEIINETVSNSDNNGCDILLRLVGGP +QAVDQYIKNLGIADMQIAVNEQEMHTVKDAQHKNWTTPAAMTQLLRLFHDGKLLKPDSQK +FLWTAMRDSVTAPGRLRSPLPAGTHLIHKTGTSDYSTVNDVGIILLPDGNPVFISVLISG +SKMSMMDTEKIIASVSGVAWDHf +>[subseq from] Beta-lactamase PSE-4 n=1 Tax=Photobacterium sp. CECT 9190 TaxID=2006084 RepID=A0A1Y6MAP5_9GAMM +--DLDITLRQTEQQIDGKIGVAVFDSQTNTSW-NFNGNKRFPMMSAFKTLVCANVLYDVQ +QHKLSLTNKIKVTKAGLINWNPITQNFVGADMSLQSVCGAAMLMSDNYAANLALVQVGGP +QGVTKFLRMIGDKTTRLDHFEPKVNYVEKGAQNDTTTPIAMMNTIKKLLTGNVLDSENKA +QLKFWMTNNMVSDGLARAVLPTGWKIADRSGGGVNGSRTLTAMVWNKQHKPLFIGIFIDN +SKKTLPELNQVVASISARIFNKy +>[subseq from] class A beta-lactamase n=1 Tax=Epibacterium sp. SM1969 TaxID=2663379 RepID=UPI00129581C0 +---LSQTISAIETRLDARVGVALIH--SDHSW-FHRPDTPVLLTSTAKTLICATVLAQND +QGLLSLDEHVPILQDDLLSYAPVSTRHVGGSLSIGDLCLATLDLSDNTAANLLLQRLNGP +ETVTAFLRSLGDEVSRLDRMEPALNS--PSEDLDTTTPRAMVETLSAIFFSDLLSQDARQ +QLRSWMGKGGVTQNLLREAAPKSWKIWDKSGAGKD-SRSLIAVIAPPKGSPWIAAIYISE +AEVDFQTRNAALRELSAAVV--- +>[subseq from] Beta-lactamase n=1 Tax=Yonghaparkia sp. Root332 TaxID=1736516 RepID=A0A0Q6RJ70_9MICO +------------------MGVLARDTSSGASI-AFGQDRRFGFASTMKAPLAGVFLDRVE +--GAARDEVVRWSAAQVEEYAPVTAERIDEGLTLAELAEAAVRQSDNLAFNLVLERLGGP +AALDAALAELGDETTEVVNLEPALNTIEPGSTDDTTTAAALAGTLEALLLGPTLDADDRT +LLLDWMSGNATGDTLIRAGAPEGWVVADKSGGAG-AIRNDVALVTRPDGAPIVIAVLTQR +DDPEAERDDSLVARAAEIALDAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=B8K1T9_SHISO +--------------------------------------------STSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNIIA------------------ +----------------------- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. RU33C TaxID=1907398 RepID=UPI0009707774 +-qELRNKINQIISTKNATAGISLKGIEDKDTL-SINGNKETPMLSVFKFHIALAVLNQVD +KGKLKLNQKFFIKKEDLLPWSPIREEYPQGNLTLDQLIRYTVSHSDNNGCDILLNIIGGT +KTVQKFINQQGIKDFTIKVNEKEMAS-FEKCYLNTTTPLATTELLEKFYKGKVLKKESTK +YLYQVMVETSRGLTWMKAGLPTGTELAHRTGISGRAAMNDVGIIKLPNGKHIVLSIYLKN +INEEMTDTEKIIADVTRAVWDYy +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus sp. AntiMn-1 TaxID=1715860 RepID=A0A192F464_9STAP +----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKSIASGVLLNNYS +--EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV +KGFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQINDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKDGQPDDKVIADAAEEAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000E67840F +----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKSIASGVLLNNYS +--EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV +KGFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQINDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKDGQPDDKVIADAAEEAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000E684E03 +----ASEIEHIEQENNVTIGVYGMNTDNSKVY-QHNADERFAFASTYKAIASGILLNNTP +--NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA +LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ +DQKNTKPDDKVIAAAAEEAMK-- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=A0A2T4SVS2_STAGA +-----KSIKDLETTYDTTIGVYGINTQDGKQI-EHHADERFAFASTYKAIASGILLNQLS +--PQDLNQKVTIKKSDIVTYSPVTEKYIGKTMTLRQLIEASMLKSDNTANNKVIQAIGGV +NAFKSELRQLGDCVSEPQRLEPDLNNYDPKKIADTTTPRAAATTLNYILTHSNMHKGNLQ +FLKELMIENETGDSLIKAGATKDDIVGDKSGQGTYATRNDLAFIYPKGQKPIILAIYTKQ +SDKNAKPNDEVIAKTAEIAIKY- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. CECT 9293 TaxID=2675057 RepID=UPI001354B835 +---LDKRINSIIKDKKATIGISVLGFENGFKY-HKNGEKRFPMQSVFKFHIAAAVLNAVD +QGTLSLHQKILLKKSDLLEWSPLRDKYLNGNIPLSEIIDYTVALSDNNGCDLLLRLIGGT +QTVQKFMDSKGIKGFQIKYNEEAMHKDWKYQYENYSTPNSTTQLLKKFYDGKLLSKESTQ +YLMKVMLGTKTGLNKMIEQLPKNTPVARKTGSSGTGAENEIGIVTLPNGNHYSITLFVSN +STETDSVNCKIISDISKVIWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Oxalobacter formigenes TaxID=847 RepID=UPI0002FF4C7B +---LQENIDAIVKDKPAQIGVVIEGFDPHQHA-GFNENTRFPMQSVFKFPVALAVLDQVD +KGKINLDETLLLKPSDLLPHSPLREKYPEANVSIGEIINETVSNSDNNGCDILLRLVGGP +QAVDQYIKNLGIADMQIAVNEQEMHTVKDAQHKNWTTPAAMTQLLRLFHDGKLLKPDSQK +FLWTAMRDSVTAPGRLRSPLPAGTHLIHKTGTSDYSTVNDVGIILLPDGNPVFISVLISG +SKMSMMDTEKIIASVSGVAWDHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. s4p13 TaxID=1367565 RepID=A0A0B5ECT0_9PSED +-----------------RVYYIKLDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEA---------------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter gangjinensis TaxID=1028742 RepID=UPI00136ABA1C +---LSAHLRIIEAASGGALGAAILDTGSGKIL-GNRLDERFAHCSSFKLSLAALAMQRSA +NGGDAFDTLLPITAEDIVSYSPVTKERVGQMMTIADLAKTTLTTSDNAAANILMRQFGGP +EAVTAFWRSVGDEISRLDRYETALNFVPPGEVRDTTTPRAMANTVRTILYGATLPSDMQQ +TLRGWMTETSTGTKRIRAGIPASWKAGDKTGTAFGSFYVDLAFAEPPEGAPLVIATYLRL +TARVEPESEAVLASVGALAT--- +>[subseq from] Beta-lactamase n=1 Tax=Microbacterium oxydans TaxID=82380 RepID=A0A0F0KHP3_9MICO +---VADELAGLEREYDATVGVMAVDTGTGESV-AYGENRRFGFASTIKAFAAAVFLQSAS +--GAARDESVRWTAEEAAAHAPVTSQHVEDGLTYAQLAEAAVRVSDNAALNLILDRIGGP +AALDDALAELGDATTEVVNDEPGLNTIESDSTEDTTTAAAFTASLARLLDGSTLSPADTA +LLVDWMSDNRTGDALIRAGAPAGWTVADKSGGAGP-IRNDIAVVTRPGHDPIIITVLTSR +NEPHADFDDTLVASAASITL--- +>[subseq from] Beta-lactamase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8RX83_9BACT +--ELQKQITEIAKEANGKVGVYATVIETGERV-SLNENEHFAMQSVVKVPISMAVLKKVE +EGNLDLEEKIGVTKEDFVPRSPIRNNNPNGVLTLRELIRFAISESDGTASDVLQHRAGDA +KGVQAYIDSVGVQGFHVERTHKEFGLDWNKQYDNWATPTAVADLLKKLFSADGISDANRE +ILIRFMRESDNPANRILAGVPKGTVVAHKTGTGAAAATNDVGIITLPNGDHIVIAIFVGD +SKANAPTRESVIAKITKAIFDKw +>[subseq from] Contig45, whole genome shotgun sequence n=1 Tax=Pedobacter lusitanus TaxID=1503925 RepID=A0A0D0F642_9SPHI +-sELREKLQRIVNAHSATIGFSLTDLRNGDTL-TVNGTKHLPMQSVYKFHLALAVLDQVD +QGKLKLDQKIMVKKSDLLPWSPLRDKYPNGEIPLSEILSFTVSQSDNNGCDILFRLIGGP +AKVNRYIHHLGIKDVAITATEEQMHQNDQIQFTNWTTPQAATELLGLFYAKKILSPASHE +FLCKVMTETSTGADKIKGLLPAGTLAAHKTGSSGTAASNDIGIVTLPDGKHFAVAAFVSM +TKEDEKATDLIIAELTKASWDY- +>[subseq from] Beta-lactamase n=1 Tax=Pseudoalteromonas phenolica TaxID=161398 RepID=A0A0S2K7Z9_9GAMM +--TLKADIELLLDSKRAKVGVSIWDQNAEPVF-SFNGDSKLPMQSVFKFHIAAAVLSEVD +KGKWSLEDKIKITPNDLDNWSPIRKKYPTGTLTLSEVIRYTVSVSDNVGCDILLSMLGGP +KKLEDYLHQSGIKDIAVIYNEENMQKVWQRQYENWTTANAANTALRQFYIKNLLSDKSHQ +FLWDVMKGSKTGRKTIRAGVPKDIQVAHKTGHSGTGAQNDIGIVFLPSGQHYYISVLVSD +SYETSETNQNIIAKISELTWQFf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. CBTAP 102 TaxID=2135644 RepID=UPI000D775C10 +-qELRNKINQIISTKNATVGISLKGIEDKDTL-SINGNKETPMLSVFKFHIALAVLNQVD +KGKLKLNQKFFIKKEDLLPWSPIREEYPQGNLTLDQLIRYTVSHSDNNGCDILLNIIGGT +ETVQKFINQQGIKDFTIKVNEKEMAS-FEKCYINTTTPLATTELLEKFYKGKVLKKESTK +YLYQVMVETSRGLTWMKAGLPVGTELAHRTGISGRAAMNDVGIIKLPNGKHIVLSIYLKN +INEEMTDTEKIIADVTRAVWDYy +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000E69920A +----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT +--EKEINKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI +SSFKAALQHLGDHVSDPQRLEPKLNDYDPTNTADTTTPRAAAHTLNELLTSKQMDTKNLK +LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK +DDKEGTPDDKVIAKAAQIAIK-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Pseudoalteromonas phenolica TaxID=161398 RepID=UPI00110A1B2F +--TLKPDIELLLDSKRAKVGVSIWDQNAEPVF-SFNGDSKLPMQSVFKFHIAAAVLSEVD +KGKWSLEDKIKITPNDLDNWSPIRKKYPTGTLTLSEVIRYTVSVSDNVGCDILLSMLGGP +NKLEAYLRQSGIKDIAVIYNEENMQKVWQRQYENWTTANAANTALRQFYIKNLLSDKSHQ +FLWDVMKGSKTGRKTIRAGVPKDIQVAHKTGHSGTGAQNDIGIVFLPSGQHYYISVLVSD +SYETSETNQNIIAKISELTWQFf +>[subseq from] Beta-lactamase n=1 Tax=Citromicrobium sp. RCC1885 TaxID=1647104 RepID=A0A0P7AD35_9SPHN +-eQLAAQIDGLEAASGGRLGLALFSQDEGLLF-AHRGAERFAMCSTFKLALAAMTLETSG +----VREERLDFGEDDILSYAPYAKERAQIGMSGLEAAHHAVTLSDNTAANLLLARLGGP +EAFTAWLRDAGDRVTRLDRNEPALNENAPGDPRDTTTPEAKAELVGNLLWGDRLSATDRS +ILHGWLVETSTGMARLRGGLPDGWNAGDKTGTCGQPEFNDIAVFETPAGSHYVLAAFLDR +PTGTSAEADAVLADAARAVAE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WX07_9BACT +---LERAIKRLAESSGGIVGVSAIHIESGRRV-SVNGSLRFPMASVYKLPIALRVLQRVD +RGELRLNAPVTLSTHDFRPHSPIVEFANNKPLPLERLLELMLGESDNSASDALLRLAGGP +AAVTNRMQALGIMGINVSRPEGQLILAYADDPRDTSTPDAMADLLVRIQRRDVLEPASME +RLLQITTATQTGPARLKGLLPIGTVVAHKTGTMG-GTTNDVGIVTLPDDGHLAIAVFVKA +STKDVPERERAIAEIARTVYDFf +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=A0A1E5TG47_9STAP +----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS +--EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV +KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTSTPRAAAQTLNTILTSDQISDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKDGQPDDKVIAYAAEEAI--- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=UPI000E697F1C +-----KSIKDLEATYDTTIGVYGINTQDGKQI-EHRADERFAFASTYKAIASGILLNQLS +--PQDLNQKVTINKSDIVTYSPVTEKYIGKTMTLRQLIEASMLKSDNTANNKVIQAIGGV +NAFKSELRQLGDCVSEPQRLEPDLNNYDPKKIADTTTPRAAATTLNYILTHSNMHKGNLQ +FLKELMFENETGDSLIKAGAAKDDIVGDKSGQGTYATRNDLAFIYPKGQKPIILAIYTKQ +SDKNAKPNDEVIAKTAEIAIKY- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000935D6A7 +----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT +--EKEINKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI +SSFKAALQHLGDHVSDPQRLEPKLNDYDPTNTADTTTPRAAAHTLNELLTSNQMDTKNLK +LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK +DDKEGTPDDKVIAKAAQIAIK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A345N875_ECOLX +---------------------------------------------------AAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGPTNDIAVIWPKDRA---------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Citromicrobium sp. RCC1897 TaxID=1812182 RepID=A0A2P0B2D6_9SPHN +-eQLAAQIDGLEAASGGRLGLALFSQDEGLLF-AHRGAERFAMCSTFKLALAAMTLETSG +----VREERLDFGEDDILSYAPYAKERAQIGMSGLEAAHHAVTLSDNTAANLLLARLGGP +EAFTAWLRDAGDRVTRLDRNEPALNENAPGDPRDTTTPEAKAELVGNLLWGDRLSATDRS +ILHGWLVETSTGMARLRGGLPDGWNAGDKTGTCGQPEFNDIAVFETPAGSHYVLAAFLDR +PTGTSAEADAVLADAARAVAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga terrae Kim and Jung 2007 TaxID=408074 RepID=A0A1H3YVC1_9BACT +----RKEITGTAASVKARVGVSVLS--DRDTL-TIRGNKRFPMQSVFKFHLGLLVMHLVD +EGKLSLQQQVHFTPEDMALWSPIAKKYPGGNLSLEEVLKSTVSTSDNIGCDKLFELVGGP +AALNKYLHGLGATDLSIVATEKEMHADWDVQYRNWTTPREATRLLKAFDEGKILKPASRD +VMMRFMTTNTNINDRLSGLLPAGTKVAHKTGTSDTAATNDIGIVALPDGRHYYIAVFVSD +SWEQGAKNNRVIAEISRKAWDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Larkinella sp. BK230 TaxID=2512173 RepID=A0A4R8CC95_9BACT +-qRLNQELERIAKLAKGKVGLSAVHLESGKQI-SMNLQERFPMASTVKVAIAVELLTKIE +KGELSLRTMVDLKPSDLHPGSGTLETLFAKPLSVENLLELMMVISDNSATDILLNLVGGV +EPVRARLKALGIEGMSVDRTIVQLIAKLEQDPRDTSTPAAMVNLLTQIYQAKALKPESRD +LLLAVMERCRGGLARIKGYLPPETVVAHKTGSLNSSATDDVGIITLPGDGHIAIAVFITS +SSQPLAEREQTIAHLSRTVYDYf +>[subseq from] Beta-lactamase n=1 Tax=Francisella sp. TX07-6608 TaxID=573568 RepID=A0A1S2WWX4_9GAMM +--QITNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKHSM +TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL +KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILNKKHRL +MFKQWLIASNTSNNRIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ +SQKNAKPNSKIVREVTKILLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma agri TaxID=1987381 RepID=UPI0013DBB930 +--SLRSQLERTASAAQGKVGVAATLLETGESI-ALQGDQRFPMQSVYKLPIAMVALHLVD +QGKLTLDQPVRVDKVEYVSHSPLRDKSPDGTVSVSELLRYAVSESDGSASDVLMRLVGGP +NVIMTYLNSLGIKDMIVANTEKELGADNAVQYRNWAKPTEAVALLRLIQQGRGLSESSRA +LLLRIMTETETGLHRLKGQLPAGTVVAHKTGTSWTAATNDIGLITLPSGRHIALAVFVSD +ARADQKTREAVIANLSRTIWNYw +>[subseq from] Uncharacterized protein n=1 Tax=Erythrobacter sp. QSSC1-22B TaxID=1860125 RepID=A0A1A7QFM0_9SPHN +--RLEAKLRIVEAGAGGQLGVFALDTQTGLGL-GHRQTERFGHCSSFKASLAAMVLQLDA +DGTISADEHVRWTRDQLMAVSPFTTERLEQGATLHELAEATQKYSDNAAANILLARLGGP +QALTAFWRRMGDDASRLDRTEPELNNVPPGELRDTTTPRAMATTLARMLYGGGLDAQAGE +RLKGWMHDTPTGLRRVRAGLPEGWHAGDKTGTSIGGLYVDIGFIEPQQRAPLTFATYYRA +PTAMDPVSEAVLAQAGSIIA--- +>[subseq from] Beta-lactamase n=3 Tax=unclassified Caulobacter TaxID=2648921 RepID=A0A257WV64_9CAUL +--DLTAQFQTLADQAPALLGIAVRDAQTGQTI-AFNGQTRFPLQSVFKAPLGAAVLAEVD +RGRIRLDEVITIRDIDLSPFSPIADAWPGRTYTVAELLERASGASDNTAADVLMKRIGGP +GALTAWLSQKKIMDFRIDRYERQLQPDYLADPRDTATPVAAVRFLAALRAGKLISKASTD +RLLGIMTATTTGPGRLKAALPDGASLAHKTGGARTDASNDIGIYELKDGRRFAVAVFLSG +STASDEARDAVIAEVGRIVLK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium arthrosphaerae TaxID=651561 RepID=A0A1B8ZR25_9FLAO +-kDLKNKIHEIISAKNATVGVSLKGIEDQDTL-SINGNKKTPLMSVFKFHIALAVLNQVD +KGKLKLDQKFFIKKEELLPWSPIRDQYPKGNLTLDQLLRYTVSHSDNNGCDILLNIIGGT +AAVQKFINRQGIKDFTIQVNEQQMSS-FDKFYLNTTTPLATTELLEKFYNGKVLKKETTK +YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISDRAAMNDVGIVKLPDGKHYILSVYLKN +INEEMADTEKIIADISRAVWEYy +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacteraceae bacterium TaxID=2026738 RepID=A0A2D9PCG8_9SPHN +-qDLAARISEIETASGGRLGLALHSPDKGLVY-AYRGDERFAMCSTFKLALAALTLDTPG +----LREKRLHFGAGDILSYAPYAKERASSGMSGLEAAHHAVTLSDNTAANLLLAEVGGP +DGFTRWLRSMGDEATRLDRNEPALNGNAPGDPRDTTTPTAHADLVGTLLWGDRHAQADRA +LLQEWLVETTTGMNRLRVGLPGEWRAGDKTGTCGQGEVNDIAMFETPDGSRYILAAYLDR +ADGSASDAEARLAEAARAIAD-- +>[subseq from] Beta-lactamase n=1 Tax=Francisella adeliensis TaxID=2007306 RepID=A0A2Z4XYM5_9GAMM +--KLAKDIKKIEVKHGGKIGVYTINRNNWKNF-SFQSSFYFPVCSTYKILVVGAILKQNM +TDKNLLNEKIKISPNSIAGYSPITNKHLNKKMTVAELCHASI-LSDNTATNLLVEKLGGL +EKLSEFNLSLGDHATKIADKEPEINDVNLRTNINKTTPKIMTRDINKLAFNDILDKKHRL +LFKKWLKDNDTGKNRITAGAPSNWLVGDKTGTCEYGTTNDVAIIWPNNSRAIAMSVFYTQ +TEKNAKPNEKIIKEVSQLVLK-- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingosinicella microcystinivorans TaxID=335406 RepID=A0A495RSS6_SPHMI +-kAVDTEVERLAAGAGGVVGIAAWRLDKGSRV-LFNADASFPMASTYKVPLAGKIFDMVD +KGQIRLDTMLDVPQEMMSPSEVIADRFIHSGLSVHNLLEVMLTQSDNTATDVLMKAAGGP +QAVTAWARAQGVTAMRVDRDTNRLLRTFDADPRDTASPAAMATLLTRMFAGKALSPESTK +AFTAIMERCRTGAARLPGQMPPGTIVAHKTGTIG-GTVNDVGMVSLPDGTGVVIAAYVKT +SAAPTADRERAIAEIARTIRDYf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000853BD06 +----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS +--EKDLNKKITINETDIVEYSPVTENYIGKQMTFKDLIKASMLQSDNTANNKIMEELGGV +KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD +LLKQVMIENETGDSLIKAGAPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKDGQPDDKVIADAAEEAI--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0N9HCR5_9BACT +-dQLRRQIEEIVSTKRAVVGVSISDAGGKSIV-LVNGDKRFPMQSVFKFHIGLKMLSEID +KGTFSLDQKIEIKKSELLPYSPIREKYPEGTLSIAEILEYTVSMSDNVGCDVLLKLLGGP +LAVENYFAGNKFNNISIKINEEVMQGNWDRQFENWTTPKAAGNVLRAFYARKLLSAKSHE +FIWKVLRETSTGANRLKGQLPAGTVVAHKTGWSGTAAVNDIGIVFLPNGKHYFISVFVTE +SKEDFAANEKIIADVSKAAWDYf +>[subseq from] Gll0595 protein n=1 Tax=Gloeobacter violaceus (strain ATCC 29082 / PCC 7421) TaxID=251221 RepID=Q7NN19_GLOVI +---LHRQIARLAERLGGRVGAAIVHVESGRAI-ALKGAERFSMASVYKLPIAIAILDMVD +RGELDLTRKLTVKASDLRPGSPLAERRDAVGLSVRELIELVMIYSDNSASDLLFDLAGGG +EAITKRLQTLKIAGLRVDRPELELLAQYRLDPRDTSTPEAIGRLLVRLQRGDILKPESNR +LLLGIMERCATGVQRIPGNLPAGTIVAHKTGTNA-GGNNDAGIITLPGKGHLAVAVFVQT +PGQPSAERERLIAEIARAGFDFf +>[subseq from] Beta-lactamase class A n=1 Tax=Shimia aestuarii TaxID=254406 RepID=A0A1I4SHV0_9RHOB +---VAAAIEQFAAKHVGRLGFAAQEIGGDEVI-ALNGDETFAMASTYKMAIATAIMDRVD +KGELSLDQMVDITPDMMMIDAALSDTFVHPGLSVANLMEIMITESDNTATDTLIGLAGGA +AAVTENLRRLGITDFRVDRTTGEIIGDFEADPRDHATPLAMLQLLLAIDSGTAMSAESRD +FLIDIMSRTRTGAARLKGLLPRGTPVAHKTGTIG-GVANDVGYITLPDGRRFAVAVFTKS +SVSSEADRDRAIAEVARSLYDYf +>[subseq from] Beta-lactamase n=1 Tax=Pararheinheimera mesophila TaxID=1547515 RepID=A0A3P3QQG0_9GAMM +---LKEQIESVVSGKKATVGVAVWGPDDLEPL-LVNPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQSVTVNRARVLQWAPLMKDYQGDEVPLQQLLQYSVSHSDNVACDLLFELVGGP +AALHDYLHSIGIKETAVVANEAQMHADDQVQYQNWTSMKAAAQILKKFEQKTLLSETSQA +LLWKWLVETTTGPERLKGLLPAGTVVAHKTGYSGTAATNDIGVIVLPDGRPLLVAVFVKD +STESTRTNEAIIAQVAELAYQ-- +>[subseq from] Class A beta-lactamase n=1 Tax=Chitinophaga sp. K20C18050901 TaxID=2291814 RepID=A0A3E1P3I9_9BACT +--ALRKTIDSIVTHSKAHIGVSALLLETGDTL-SYRGNDHYPMQSVYKFPISFAILHQVD +LGKYKPDQKITITSDDIMPHSPIREAHPHGGMTIREISRYNIQESDGTACDVLLRLLGGT +KKTNAYIRSLGVTGINIATTEKEQQQDDTTQYHNWATPIAITQLYKVFLRNNVLSKQSYD +ILWKDLAESHPGAKRIKGLLPPGTVVAHKTGTSGTAATNDSGIIILPNGKHLILTIFVSD +SKGSEAEREGWIAQISKAVYDHf +>[subseq from] Uncharacterized protein n=1 Tax=Sphingomonadales bacterium 12-68-11 TaxID=1970586 RepID=A0A257YDT6_9SPHN +----EAALAALEARSGGRLGACIIDTATGRTA-GWRSSERFAHCSSFKLSLAALVLQGAQ +AGRWQLDHRLHWTQGDLMGNSPVTSAHVAEGLTAAELARATLVTSDNAAANVLLRWLGGP +QAMTAFWAAIGDTTSRLDRLEPDLNVVPPGSVLDTTTPAAMAATVARLVTGDVLDEAGRA +MLMSWMVEVQTGTRRLRAGFPAGWVAGDKTGTGLSTIYVDLAFGGPAARAPLVVAAYFV- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SD47_9BACT +-dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKID +KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVHLLKKFYKNEILSKNSYD +FLLNTMIETTTGPKRLKGLLPDGTVVAHNTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WXU9_9BACT +-sSLERAIKRLADNSGGVVGVSAIHVETGRRV-ALNGAMRFPMASVYKLPIALQLLHKVD +RGELRLSDSVTLSEQDFRPHSPIAEFANHKPLSIERLLELMLGESDNSASDKLLALAGGP +AAVTARMRALDITGLDISRPEGRLALAFADDPRDTSTPDAMAQLLVRVERREVLEPASME +RLLQITTATQTGPLRLKGLLPAGTPVAHKTGTMG-ATTNDVGIITLPDGGHVALAVFVKG +STLDVPSRERVIAEIARTIYDYy +>[subseq from] class A beta-lactamase n=1 Tax=Coxiella burnetii TaxID=777 RepID=UPI0002DAEEFC +------------------------------------------------------------ +------------KKNELVSYSPITKNHINGGITVSELCAAALTLSDNSAANLLIKKLGGL +TAINAFARSIGDKQFELDRLEPQLNSAIPGDIRDTTTPEAMANSLKRLTLGDILAFPQRI +QLQTWLKNNTTGNAKIRAGVPKDWIVGDKTGSGGYGTTNDIGIIWPPKRAPIVVAIFFTK +NKKGAVSPDSIIERITRILM--- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. CECT 9393 TaxID=2675058 RepID=UPI001360AFBB +---LDKRINSIIKDKKATIGLSVLGFENGFKY-HKNGEKRFPMQSVFKFHIAAAVLHAVD +QGTLSLHQKILLKKSDLLEWSPLRDKYPNGNVPLSEIIDYTVALSDNNGCDLLLRLIGGT +QTVQKFMDSKGVKGFQIKYNEEAMHKDWKYQYENYSTPNSATQLLKKFYDGQLLSKESTE +YLMKVMLGTKTGLNKMIEQLPKNTPVARKTGASGTGAENEIGIVTLPNGNHYSITLFVSN +STETDSVNCKIISDISKVVWDYf +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A345N867_ECOLX +---------------------------------------------------AAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSRGYGTTNDIAVIWPKDRA---------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Eudoraea adriatica TaxID=446681 RepID=UPI00035E5CB4 +-kSIAQKIEKLTEGLVGRIGVAAQELSSGLNV-SINGDENFAMASAYKIAIAAKVMDLVD +KGELSLDQMVEVPQDMYVAVVAIAERFPYSGFSLANLIYPMITESDNTATDVCLQLAGGP +TAVTENLRRLGITDFRVDRSVREILMNFEADPRDHTTPNAYLQLLLAIDGGTAMSPKSRE +FLLGVMSRTRTGAGRLKGLLPKGTPVAHKTGTLG-GVANDVGYITLPDGRQFAIAVFTNS +SKTPASDRERAIAEVARALYDFy +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=A0A512S8G6_STAGA +-----KSIKDLEATYDTTIGVYGINTQDGKQI-EHRANERFAFASTYKAIASGILLNQLS +--PQDLNQKVTINKSDIVTYSPVTEKYIGKTMTLRQLIEASMLKSDNTANNKVIQAIGGV +NAFKSELRQLGDCVSEPQRLEPDLNNYDPKKIADTTTPRAAATTLNYILTHSNMHKGNLQ +FLKELMIKNETGDSLIKAGAAKDDIVGDKSGQGTYATRNDLAFIYPKGQKPIILAIYTKQ +SDKNAKPNDEVIAKTAEIAIKY- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000D1D3F73 +----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP +--NNKLNKKIKINEQDIVAYSPVTEKYIGKTRSLKSLVQASMLQSDNTANNKIINEIGGI +EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA +LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ +DQKNAKPDDKVIAAAAEEAIK-- +>[subseq from] TLA family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella michiganensis TaxID=1134687 RepID=UPI00102009E3 +-dSLKNSIEKYLKDKKAKVGVAVLGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKLD +KENISVDKKLFVKKSDLQPWSPLKDKYPNGNLSFSEIIKSTVSHGDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD +FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus sp. LCT-H4 TaxID=1914308 RepID=A0A1S2MKQ8_9STAP +----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT +--EKEINKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI +SSFKAALQHLGDHVSDPQRLEPNLNNYDPTNTADTTTPRAAAHTLNELLTSNQMDTKNLK +LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK +DDKEGTPDDKVIAKAAQIAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Coxiella burnetii TaxID=777 RepID=UPI000B08C16B +------------------------------------------------------------ +------------KKNELVSYSPITKNHINGGITVSELCAAALTLSDNSAANLLIKKLGGL +TAINAFARSIGDKQFELDRLEPQLNSAIPGDIRDTTTPEAMANSLKRLTLGDILAFPQRI +QLQTWLKNNTTGNAKIRAGVPKDWIVGDKTGSGGYGTTNDIGIIWPPKRAPIVVAIFFTK +NKKGAVSPDSIIERITRILM--- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter litoralis TaxID=39960 RepID=A0A074MHP5_9SPHN +---MQATLRLIEAKAGGTLGVDIYDTQTGVSV-GLNRDRRFGHCSSFKLSLAAMVLALDA +ADEIDASRRVTWTKDDLMFVSPFTEKRLAEGASLLELAEYTQKYSDNTAANVLLRELGGP +AALTGFWRSIGDGVSRLDRTEPELNNQPVTEYRDTTTPAAMARTVAKLLYGDVLPEPSEA +LLRQWMIDTPTGARRVRAGLPEGWVAGDKTGTSIGSLYVDIGFARPPEHPPITFATYYRA +RETHDPASEAALASVGEVI---- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga dinghuensis TaxID=1539050 RepID=A0A327WD70_9BACT +-qSLRAEIAAIAGKIPAKVGVSVRVLETNDTI-SFNRDLRLPMQSVYKFPISMAVLDQVD +KGRLTLHQPIKIEKADLTTVSPLRDKYPNGGLTIDELLDYNIRSSDGSACDILLKVLGGP +AAANKYIHQLGIKDINIATTEEAQQNDAKTQYKNWCTPSAMTLLLEKFYLKPLLSDSSKR +YLYHLMATSGPGKRRLKAQLPAGTEIAHKTGTSWTAATNDAGIITLPNGKHVAITVFVSD +AKASEAEREGTIAAIAKAVWDAy +>[subseq from] class A beta-lactamase n=1 Tax=Sphingorhabdus sp. IMCC26285 TaxID=2509718 RepID=UPI001365FF42 +----ETALAELERSAGGKLGATILNTRTGQSI-SHRGGERFGMCSSFKLALAALILRKAD +GGELDLDSFVPITSSDMVYFAPVVTENLAKGMTIGAMAEAAQVFSDNVATNKLLAILGGP +AGFTAAMRAIGDVQTRLDRLEPEMMLVDVGDPRDTTTPFAMAHTVAKMTTTNWLSVGART +KLLGWMEATKTGSKRIRAGLPADWRSGDKTGTGMPDRYNDIAIAWPNKGAPIIITGYYES +PVKSRDEDQAVLAELGKI----- +>[subseq from] Serine hydrolase n=1 Tax=Halioglobus lutimaris TaxID=1737061 RepID=A0A2N5X5X1_9GAMM +---VATSIEQFAAKLVGRIGFAAQEIGSDEVI-ALNGDETFPMASTYKVAIATAVLDRVD +KKELSLDQLVEITPDMMMIDAALSDTFVHPGLSVANLMEIMITESDNTATDTLIGLAGGA +AAVTENLRRLGVTDFSVDRTTGEIIGDFEADPRDHATPLAMLKLLLAIDSSTAMSAESRD +FLIDVMSRTRTGAARLKGLLPKGTPVAHKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS +SETSEADRDRAIAEVARSLYDYy +>[subseq from] class A beta-lactamase n=1 Tax=Chitinophaga rhizosphaerae TaxID=1864947 RepID=UPI000F805A89 +--SLRLQISAIAAEAKGVVGVSIQNFATGDTL-TLNDTARLPMQSTFKFPIAMTVLKQVD +EGKLTLEQKLPVTPDDLFEYSPLQDSFPKGTKTIANLIYLMVAQSDNIACDVLIRKVGGC +KVINDYVHSLGVKNIEIVMTEEEMNGGFDLQFKNWAQASAYSQLLDILRKGTALSKPSND +FLMNTMLATTTGKNRLPGLLPAGTPVAHKTGSGSTKATNDAGIITLPNGQQLAVSVFVSM +SAADEATRDAVIAKIAKAAYDHy +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. YR203 TaxID=1500291 RepID=A0A1M5GKZ4_9FLAO +-sALEQKISSITQGKKATVGVSVLGFENNFKY-SKNGDKKLPTLSVFKFHIACAVLDLVD +QKKLSLEQKLFLKKEDLLEWSPIREKYPEANLSLSEILDYTVSLSDNNGCDILLRLIGGP +QTVQKFMDSKGVKDFQIKYNEDEMHKNWKALYENYSTPNSAVQVLKKFYDGALLSKKSTD +YLMQIMLGTKTGTNKIIEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAIFVSN +STETEVVNCKIVSDISKAVWDDf +>[subseq from] Class A beta-lactamase n=2 Tax=Novosphingobium sp. FSW06-99 TaxID=1739113 RepID=A0A102D8B4_9SPHN +-------LAALERRAGGRLGVAVRDTASGRGF-GWRQDERFAHCSSFKLSLAAMVLAQID +AGQARGDEVLAYSVLDILPASPVTEAAAGKELPILTLAEAAVERSDNLAANLLLARFGGP +AALTAFWRTLGDDVSRLDHHEPDLNRVAPGAVHDTTTPTAMAQTLGRLLTGPVLSGGSRA +TLWGWMKACSTGLGRLRAGLPEGWQAGDKTGTWNDGKVVDLALVLAPDGAPLAVTAYYEP +TGTPRPADEAVLAAVMRIATD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium taihuense TaxID=1141221 RepID=A0A1G9RST5_9FLAO +---LDQKINTIIKGKKATVGVSVLSFEDHFRY-NKNANKKLPMLSVFKFHIAAAVLDWVD +QGKLSLDQKIFITKKDLPEWSPIREKFPNGNMSLNEMIYYTVAWSDNNGCDILLRLIGGT +ETVQKFMDSKGVKNFQIKNNEEQMHKGIQYLYENYTTPHSLAQLYKDFYQGKILSEKSTE +YLYNIMLNTETGTNKLKEQLPQK-AVAHKTGSSGKTAENDSGIVTLPNGNHYSIVVFISD +STEPEKVNCQMISDISKTVWDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A3KEX6_STEMA +----ATDFAALEKACSGRLGVTLLDTGSGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDPALLDQRLPVRAQDILEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRASGDTITRSDRLEPELNSFAIDDPRDTTTPAAIAATLQRLVLGDALKPASRQ +QLADWLIDNETGDACLRAGL---------------------------------------- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Tropicimonas sp. IMCC6043 TaxID=2510645 RepID=A0A4V1V657_9RHOB +--SVGAAIERAAAGLAGRIGSAAQEIGGDQVI-AFNGDESFPMASTYKVAIATAIMDRVD +RGELSLDQMVDITPDMMMIDAALSDTHPGVQLSVANLMEIMITESDNTATDTLIGLAGGA +AAVTENLRRLGITDFRVDRTTGEIIGDFEADPRDHATPLAMLQLLLAIDSGTAMSAESRD +FLIDVMSRTRTGAGRLKGLLPRGTPVAHKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS +SETSEADRDRAIAEIARSLFDYy +>[subseq from] Beta-lactamase n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A317I174_9PROT +--------AQAARTVDGKVGASVLVVETGERA-GVRAADRFPMQSVYKFPIAMAVLHLVD +AGKLKLDDPVTVARAELVPHSPIRDAHPQGDMPLRDILRYAVAESDGTASDVLVRLAGGC +GSVAAYLRDLGIANVTIATTELEMSSGDMVQYRNWATPDGMTGLLAAFQKGAGLSAESRA +LLLQWMTESTPGPKRLKGLLPAGTVVAHKTGTSGTRATNDVGLITMPDGRHLAVTVFVAD +SRAPLEAREGVIARVARMAWDQw +>[subseq from] Serine hydrolase n=1 Tax=Larkinella rosea TaxID=2025312 RepID=A0A3P1BPM5_9BACT +-qRLNQELERIAKLAKGKVGVCAVHLESGKQI-SLNLQERFPMASTVKVAIAVELFTKIE +KGELSLRTMVDLKPSDLHPGSGTLETLFAKPLSVENLLELMMVISDNSATDILLRLVGGA +EPVRARLKALGVEGMSVDRTIIQLIAKLEQDPRDTSTPAAMVNLLTQIYQAKALKPESRD +VLLAVMERCRGGLARIKGFLPPETVVAHKTGSLNSSATDDVGIITMPGDGHIVIAVFITS +SAQPLAEREQTIAHLSRTIYDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium humi TaxID=493375 RepID=A0A1H6AFS0_9FLAO +--NLKAEIQNVIKDKNATIGVSILGFEKPFEL-NINGDKHLPMQSVFKFHIALAVLNLVD +TGELNLNQKIFIKKSDLLEWSPIREKYPNGNLTLAEIIKYTVAQSDNNGCDILLKLIGGV +QTVQDFTNSKAVKDFQIKYNEEKMHQDWNAQYENYSSTNSLVNVLKAFYNDKIVSKSSTD +FLMKILIGTTTGQNKLKALLPKTAIIAHKTGSSGTGAENDMGIVTLPNGNHYAICVFVSN +SKETEAINCKIIADISKLVYE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. s3p12 TaxID=1367561 RepID=A0A0B5ECR8_9PSED +---------------------IELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEA---------------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000C33B09A +----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT +--EKEINKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI +SSFKAALQHLGDHVSDPQRLEPNLNNYDPTNTADTTTPRAAAHTLNELLTSNQMDTKNLN +LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK +DDKEGTPDDKVIAKAAQIAIK-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium gleum TaxID=250 RepID=A0A4U8WA17_9FLAO +---LDQKINTIIKGKKATVGVSVLSFEDHFRY-NKNANKKLPMLSVFKFHIAAAVLEWVD +QGKLSLDQKIFITKKDLPEWSPIREKFPNGNMSLNEMIYYTVAWSDNNGCDILLRLIGGT +ETVQKFMDSKGVKNFQIKNNEEQMHKGIQYLYENYTTPHSLAQLYKDFYQGKILSEKSTE +YLYNIMLNTETGTNKLKEQLPQK-AVAHKTGSSGKTAENDSGIVTLPNGNHYSIVVFISD +STEPEKVNCQMISDISKTVWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Asaia sp. As-1742 TaxID=2608325 RepID=UPI00141D7ED8 +---------RYEKISGGRLGVHIFCPENGTAL-SWRGEERFRMCSSFKASLAACVLARCD +RDEDDLTRRIAFRESDFKEWAPVANRNRDAGLSLAALCAGAVTMSDNICANMLLRHIGGP +AALTRFWRDSGDEITRLDAYEPELNRPSANPDDNTTSPVAMARTLHRLIHGTLLHPNSAA +LLRSWMINCTTGTQRLRAGLPAHWVVGDKTGNNGKDIAADIAFASPDAGKSVIIATYTAG +GTPDETQFRRVFHDIGALA---- +>[subseq from] Beta-lactamase n=1 Tax=Chryseolinea flava TaxID=2059302 RepID=A0A364XYF2_9BACT +--RLKNSIKKILSNKSAVVGVSIIGTNGKDTL-SIHGDRRFPMQSVFKFHIALAVLSEID +KGKLSLDQKIEISKDELLPYSPLRDENPNGGFTIEKLIQYSVSISDNTACDALIRLIGTP +KTVEAYIKRSGINDIQITFNEEDMQAKWENMFQNWTTPKAASETLRLFYESNLLSKSSYD +FFWKTNRETTTGKMRIKGQLPAGTIVAHKTGSSGTAALNNIGIVFLPTGEYFIISVFVSE +SKEDSATNEKIIADIAKATYDFy +>[subseq from] BlaZ family class A beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A657ZLF9_9STAP +----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT +--EKEINKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI +SSFKAALQHLGDHVSDPQRLEPNLNNYDPTNTADTTTPRAAAHTLNELLTSNQMDTKNLK +LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK +EDKEGTPDDKVIAKAAQIAIK-- +>[subseq from] class A beta-lactamase n=2 Tax=Agromyces sp. LHK192 TaxID=2498704 RepID=UPI000FD98E8A +----ARALADLEREASVSIGVVAAVRGERRAF-RYRADERFPMCSLFKTLAAASLVQQRG +YDDVYWTTPIPYTRADIVIDSSVLGENPPMQASPDLMCDAAVRASDNTAGNLLLRELGGP +AAITAFAASLGARNTRLDRWEPDLNQALPGDLRDTSTPDDIAMLYEALLLDDAAGVLASA +RLREWMLRCQTSGKRMRNGLDGPYELADKTGGGSYGVVNDAGVLWRPGHPPMTIAIMTRT +DRSDATRNDAVVAEATRIVV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Pedobacter duraquae TaxID=425511 RepID=A0A4R6IKH8_9SPHI +--LLRNEIASIALSAKGRVGVAMEVLEDRDTL-SYHGGSRVVMQSVFKFPIAIAVLHQVD +LGKLKLDQMLHIIKEDLPKYSPLRDKYPEGNLPVSELLSYMVSLSDNDACDILLNKIQLK +SEVERFIHNVGIKDIEIRATEAEMMANWDAQYTDWTTPDAMLKLLRISYTDTILRPSTKS +FLWEIMEATSTAPKRMKGLLPPGVIVAHKTGTSSTNATNDVGVITLPNGKHLAIAVFVTD +SYADPVTRDLVIAKITKAAYDTf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Mucilaginibacter polytrichastri TaxID=1302689 RepID=A0A1Q5ZZ70_9SPHI +-eTLRNHIAEIAKEAKGIVGVSVLNIETGDTL-SYNGYKHFPMQSVMKYPIAITVLHEID +KGKFTIDQPIHVDKSDYYDYSPLKDKYPEGNVSIKELLSYMVSLSDNIACDVLLKTLGGT +DKVDAYMHTIGINNIAIKASEYQMAQAWDVQFTNWVQPKELTRLLKISFKPDFLSPPSYA +YLWKIMQATSTGPKQIKGLLPEGTIVYHKTGRSGTNATNDVGIITLPDGIHLAIAILLSN +SSVDMPTRESVIARIAKAAYD-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000D1D428E +----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT +--EKEINKKIQIQQKDIVAYSPVTEKYVGKQMSLKALIEAAMLKSDNTANNYIIGEIGGI +SSFKAALQHLGDHVSDPQRLEPKLNDYDPTNTADTTTPRAAAHTLNELLTSNQMDTKNLK +LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK +DDKEGTPDDKVIAKAAQIAIK-- +>[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T6C7_9BACT +--DVSQAFKLAKQKSQGNLGAAVMDFQTGECI-DINGDLPFPMQSVYKLPIAINVLSQVD +KGTLKLDQRIQVTPADYVTHSPLRDKHPDGITTLNSLLELMAGESDGSACDVLLRLTGGP +RATSRFLQEIGTTAVHVLNTEKEIGANSSVQYANTATANATVGLLKTLYNGRTLSEESRS +RLLNIMTNTPTGPRRIKGKLPPTYSVAHKTGSSRTAATNDVGIITFPDGRAVAIAVFVND +SRADSATRDEVIADVAAAALKYf +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium arachidis TaxID=1416778 RepID=A0A1M5H898_9FLAO +---LDQKINSLISNKKATVGISVLDFENGFKY-SKNADKKLPMQSVFKFHIAATVLDYVD +KGKLSLDQKIVLNTSNLLGWSPLRDKYPNGGVPLSEILEFTVAKSDNNGCDIMLKLLGGT +QTVQKFINSKGIKGFQIKYNEAEMHKDWNLQYENYSTMNAATDALRKFYDGKLLSKKSTD +YLMKVMLSTSTGKNKLIEQLPKNTPVARKTGSSGTGAENEIAIITLPNGKHYAIAVFVSN +STETEEVNCRMISDISKLVWDYf +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. LM2 TaxID=1938605 RepID=A0A1S6ET39_9CAUL +-------LSALEQANGGRLGFVAHDLGTGRRL-TARGDERFVYCSTFKMYLSAATLMRVQ +AGHEQFDRLIPMTAADMVSHAPVTEPAIGSSLSVERLMQAVVEVSDNPAANLLLKALGGL +DPMRAFYRGLGDDSTTVDRFEPEMNRV--DGIKDTIQSLQSATNIQRLFLDAALSAESQT +RLLGWMFASPSGADRLKGGAPAGWRVAHKTGTGGYGPTNDIGILYPPSGEPVIVAAYYHA +TPTSDAQNAAVIADATRLAL--- +>[subseq from] VEB-PER n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SCW7_9BACT +-dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAALDKLV +KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD +FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] Beta-lactamase n=3 Tax=Francisella tularensis TaxID=263 RepID=A0A0E2ZJR0_FRATU +--QVTNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM +TDNKLLNQKIKISKNQIVEYSPITRRHINQIMTVKQLCQASMQ-GDNTATNILIEKLGGL +KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL +MFKQWLIASNTSNNRIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ +SQKNAKPNSKIVREVTKILLN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X0I0_9BACT +-qTLSKEIVTLAKKYSADVGVGII-TPEGDTV-SVNGNRRYPMQSVYKFHLALYILDQVD +QKKLSLRQEIILTKRDLLPHSPLRDSRIGMRVTLQKLLQYTVSYSDNIGCDILFRLAGGP +SKVHDFIQAHGVSDVAVIYTEEEMHADWEKQFANYSTPKSMVLLLDKFRKGEILSPSSTK +LLMELMQNTTTGTKRLKGNLPEGTIVGHKTGTSGYRATNDAGIVTLPGGRTYSIAVFVSK +SRETEETNERIIAEISRMVYDN- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WYB9_9BACT +---LEKQFEEIARKSGGRVGVRAMLLATGETF-SLNENERFPMQSVYKLPIAMAVFGRIE +AGTIKLEQMLRIGGGEVLKGSTALEKYPDGTRSVEELLGLMVSESDNTASDALLRLAGGP +REVMNYLKKLGINDMVVANFEKEMHADWQAQYRNYATPSAAVELLRAIDEANGISPPNKT +RLLKFLTESPTGPRRLKGLLPEGAVVAHKTGTSATRATNDIGILTLPDGRRFAIAVFVAD +SSADQATREETIARITRAAWTYw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A346QRV5_KLEPN +-------------------------------------------CSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNPI------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. HMWF035 TaxID=2056868 RepID=A0A2U0E0X1_9FLAO +-sSLETQINSIIKNKKAMVGISVLGFENGFTY-NKNADKKLPMQSVFKFHIAAAVLDYAD +KGKLSLDQKVSLNQSNLHEWSPLREKYPNGGVPLSEIIEYTVAKSDNNGCDILLKLLGGT +QVVQKFMNIKGVKNFQIKYNEEAMHKDWNAQYENYTTMNSAVDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGINKLIEQLPKDTPIARKTGSSGTGAENEIAIITLPNGKHYAIAVFVSN +STETAEVNCRMISDISKTVWDYf +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X3Z9_9BACT +-rDLQARIEQLVDFAKGRVGVAAELLETRAAV-SVNAREQFPMQSVYKLPISMAVMKQVD +AGKLKLDQKVQITKADYIGHSPIREKYPNGALSLTELIRFALSESDGTASDILMRLAGGA +EAVQAYLTELGINKMDLVDPEMALAKDPSVQYRNYARPAAAIELLRSLHEKRGLSDSAQA +LILKCMVESTPGAKRLKGLLPAGTVVAHKTGTSGTAATNDIGIITLPDGRHLAIAVFVSE +SPADLDTRERVIAEIAKAAYEKf +>[subseq from] PER family class A extended-spectrum beta-lactamase n=1 Tax=Rheinheimera sp. LHK132 TaxID=2498451 RepID=UPI000F8EEABB +---LKEQIETIVTGKKATVGVAVWGPDDLEPL-LLNPFEKFPMQSVFKLHLAMLVLHQVD +QGKLSLNQSVTVNRAAVLQWAPIMKEYQGDEVPLQQLLQYSVSHSDNVACDLLFELVGGP +QALHAYIQSLGVKEVAVVANEAQMHADDQVQYQNWTSMKAVAQLLKKFEQKKQLSETSQA +LLWKWMVETTTGPQRLKGLLPVGTIVAHKTGTSGTAATNDAGVIMLPDGRPLLVAVFVKD +SAESERINEAIIAQVAQAAYQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Dyadobacter sp. 3J3 TaxID=2606600 RepID=UPI0013569E8F +--RLDHELERIAKLAKGKVGVSAVHLETGKHI-SLNLKELFPMASTIKVAIAVQLFTKIE +KGELSLMTMVDLQPSDYHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT +EAVQKRMNALGIKGMSIDRTIIQLIARLQKDPRDTSSPEAMVNLLTQIYTGKALKPESRD +LLLAVMERCRGGVARLKGYLPAGTVIAHKTGSLNASATDDVGIITLPDGGHVAIAIFVSE +SGAELSEREQTIAHISRSIYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000E68826C +----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT +--EKEINKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI +SSFKAALQHLGDHVSDPQRLEPNLNNYDPTNTADTTTPRAAAHTLNELLTSNQMDTKNLK +LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK +EDKEGTPDDRVIAKAAQIAIK-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Mucilaginibacter polytrichastri TaxID=1302689 RepID=UPI000942441F +-eTLRNHIAEIAKEAKGIVGVSVLNIETGDTL-SYNGYKHFPMQSVMKYPIAITVLHEID +KGKFTIDQPIHVDKSDYYDYSPLKDKYPEGNVSIKELLSYMVSLSDNIACDVLLKTLGGT +DKVDAYMHTIGINNIAIKASEYQMAQAWDVQFTNWVQPKELTRLLKISFKPDFLSPPSYA +YLWKIMQATSTGPKQIKGLLPEGTIVYHKTGRSGTNATNDVGIITLPDGIHLAIAILLSN +SSVDMPTRESVIARIAKAAYD-- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium carnis TaxID=1241979 RepID=A0A3G8XW18_9FLAO +-sDLKKDINQIIKGKNATVAVSVLDFETNKSL-SINGNKKLPLLSVFKFHIALAVLDQVD +QGKLSLDQNIPVTKAELYEYSPFRKEFPDGNKTLAQLLRYMVAKSDNNITDILINLIGGT +KTVQKKMDKSSVKNFTIIADERKMHEGWEYLYWNTSTTNSLNAVLQKFYKGKLLSKQSTD +FLMQTMLETTTGANKLVAQLPKNIPVAHRTGSSGTAAENDIGIVTLPNGKHYAISILVSD +SMESENTNTKMIADISKIVFDYf +>[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter dokdonensis DSW-74 TaxID=1300349 RepID=A0A1A7BG25_9SPHN +--RLEAELRRIESEADGTLGVELFDTATGLAV-GINETRRFGHASSFKLSLAALLLERHA +AGAINADKQVRWSEADMVHHAPFTRDRIGTGATLRELARATQITSDNPAANILMRELGGP +AGLTAFWRSIGDNISRVDRIEPEMNNVPTSEFRDTTTPAAMARTVAKIVYGDVLPPAERA +ELKGWMVETQTGRNRVRAGLPEGWLAGDKTGTSGY-NYIDIGFAEGPKGAPITFACYFRA +RQEMLPRGEAVLAQVGRLI---- +>[subseq from] Class A beta-lactamase n=1 Tax=Cellulomonas sp. NEAU-YY56 TaxID=2483352 RepID=A0A3M2JDK0_9CELL +----AAALADLEAETGYRVGVHAVDTVTGDVV-NHRADERFGYASTIKALALGVALRGAD +--PSVLDRTLPVTAEDVAGYTPVTADRVGSSMTLADLGAAAVSLSDNGALNVVLRDLGGP +AALRAVLVDLGDTTTQVDAVEPDLNRFTPGEPARTSTPRALADGLAVFALGDELDPAVRE +VYVGWLTGSTTGDATIRAGAPEGWLVGGKTGTAGYGSRNDVAVAWPPEGAPVVVAVLTDH +PDPAAAPDDTVVARAAAIVLGAy +>[subseq from] class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI00135E5D78 +--QVTNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM +TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL +KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL +MFKQWLIASNTSNNHIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ +SQKNAKPNSKIVREVTKILLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas sp. MYb238 TaxID=2040281 RepID=UPI00129200E2 +---LQRELERLVAPFDGKVGAYVLDLRSGRHA-QVNGDAGFPMASTVKVPVAVHILAVVD +EGRLDLRQQVVLQASDIYPGGPM-DTHLTAGITVRDLLHMMLAVSDNNATDILIRLGGGP +AAVDARMRALGIDGIRVDRYIWEMLALYNADPRDTSTPAGMAALLRRIWEGRALRPDTTA +VLKAILLDCRTGQARLKGMLPDATPVAHKTGTVDE-VINDVGVIVLPGGGEVVVAVYLVS +GA-SDQARDRMIAQVARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Caulobacter henricii TaxID=69395 RepID=A0A0N7JH99_9CAUL +-kALTQSLQAVADRAPGQLGVAVCDIQTGQTV-TFNGDRRFPLQSVFKAPLGAAVLSGVD +RGEIRLDEVITIRDIDLSPFSPIAESWPGRTYSVAELLEAASGASDNTAADVLLNRIGGP +GALTAWLTQKAIPDFRIDRYERQLQPDYLTDPRDTATPLAAVRFLAALQAGHLISRASTE +RLLAIMTATRTGQGRLKAALPEGASLAHKTGGARTDASNDIGLYRLKDGRQFAVAVFLSG +STAPEDARDAAIAEVGRTVLK-- +>[subseq from] Beta-lactamase n=1 Tax=Allofrancisella inopinata TaxID=1085647 RepID=A0A4R7LIH7_9GAMM +--EISNQITKLETQYGGKIGVYLIDYNDKSNF-GYNEKFHFPICSVYKFLVVGAVLKESM +VTPNLLNEKIKINENDIIGYTPITSKNIDKKLTITELSKATM-LSDNTAANLLIKKLGGL +KNLNKFIQSLGDRDTIITADEPAINNINLRDNLNKTSPQIIAKDLNKVAFKKILNKKNQS +LFKKWLQENNTGKDRIAFNIPKEWKIGDKTGTCEYGTTNDVAIIWPKNKKPIIIGIFYTQ +VDKNAKANDIVIQKITKILLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Asaia bogorensis TaxID=91915 RepID=UPI000EFA4A4E +---------RYEKISGGRLGVHIFCPENGTAL-SWRGEERFRMCSSFKASLAACVLARCD +RDEDDLTRRIAFRESDFKEWAPVAARNRDAGLSLAALCAGAVTMSDNICANMLLRHIGGP +AALTRFWRDSGDEITRLDAYEPELNRPSANPDDNTTSPVAMARTLHRLIHGTLLHPNSAA +LLRSWMINCTTGTQRLRAGLPAHWVVGDKTGNNGKDIAADIAFASPDAGKSVIIATYTAG +GTPDETQFRRVFHDIGALA---- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=UPI0005BBC6BA +--AAQAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPVCGTYAVVAAAAILARGS +LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP +QAVTSFAHESGDTVFRLDRWEPELNLAAPGDERDTSTPVAMVDLLQQLLLGDTLREPQRA +QLTEWMNGGTRGATGIAAGVPPGWRVADKAGTGGY------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI00135F4FED +--QVTNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM +TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL +KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL +MFKQWLIASNTSNNHIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ +SQKNAKPNSKIVREVTKILLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Bosea sp. Root670 TaxID=1736583 RepID=UPI000715D47E +-dKLDKAIEGIEQQAEGRLGVALMDLRDRKLW-SHRGSETFPMQSVFKLPLAVAVLQQVE +AGKFRLDQPITVTRKDFSLHSPLAKAFKGERYPLRELIRLAAGESDNTAADLLMREIGGP +QVVTKMLRDGGIQGMSVDRYERQFQPNALKDKRDASTPEASAQFLEAFAKGNWLRPAHAA +LLTQIITETKVGADRIKAGLPAGSRLAHRTGAGLNHATNDIGIATLPDGRRFVIVTYLAG +SRADAKEREAALADVARLAVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Larkinella terrae TaxID=2025311 RepID=UPI0012AD8C6E +-qRLNQELERIAKLAKGKVGVCAVHLESGKQI-SLNLQERFPMASTVKVAIAVELFNKIE +KGELSLRTMVDLKPSDLHPGSGTLETLFAKPLSVENLLELMMVISDNSATDMLLRLVGGA +EPVRARLKALGIEGMSVDRTIIQLIAKLEQDPRDTSTPAAMVNLLTQIYQAKALKPENRD +LLLAVMERCRGGLARIKGFLPPETVVAHKTGSLNSSATDDVGIITLPGDGHIAIAVFITS +SAQPLAEREQTIAHLSRTIYDYy +>[subseq from] Beta-lactamase class A n=1 Tax=Labrenzia aggregata (strain ATCC 25650 / DSM 13394 / JCM 20685 / NBRC 16684 / NCIMB 2208 / IAM 12614) TaxID=384765 RepID=A0NUD0_LABAI +--SVGAAIEQIASGLAGRIGFAAQEIGGDEVI-AFNGDETFAMASTYKVAIATTVLDRVD +RGELSLDQLVEVPLDMFVTVNALAETFPHPGLSVANLIEVMITESDNTATDVSMGLAGGA +AAVTENLRRLGITDFRVDRTTREILMDFEADPRDHATPLAMLQLLLAIDGGTAMSPESRE +FLLGVMSRTRTGAERIKGLLPKGTPVAHKTGTAG-GIANDVGYVTLPDGRRFAIAVYTNS +SETPVSDRDRAIAEIARMVFDHf +>[subseq from] Beta-lactamase n=2 Tax=Vibrio mediterranei TaxID=689 RepID=A6CVT7_9VIBR +------------------------------------------MMSTFKTLACAKMLHDAD +SGELDKNALAPITSDKLIPWSPVTEKMVGSSITVSKACEATMETSDNTAANIVLHSIGGP +QGLTEFLRLNQDDVTRLDRIEPELNQALSGDKRDTTTPNAMNTTLHRLLFEGALNQGSKN +QLMAWMQGNTVSDSLLRSVLPQGWSIADRSGAGANGSRGFNGAIWADNRKPLVISIYLTQ +TDLSMSERNQIINEIGGLIFQTy +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=A0A1E5TQ52_9STAP +----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS +--EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNMANNKIMEELGGV +KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD +LLKQVMIENETGDSLIKAGAPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKDGQPDDKVIADAAEEAI--- +>[subseq from] Uncharacterized protein n=1 Tax=Sphingomonas sanguinis TaxID=33051 RepID=A0A147ILI6_9SPHN +-----VRLRAIERAAGGRLGAFVLDTGSERSF-GWRADERFCHCSTFKLSLAAMALREID +AGRLDPMETLGFSQTDIVAYSPVVEQNLDKGLPILALAKAVQITSDNAAANVLMRRLGGP +DALTRFWREIGDNVSRIDGYEPSINVIPPGTIENSTTPRAMAKTVRRIVLGDVLGKASRD +RLRGWMAATQSGSKRIRAGLPAGWRGLDKTGTGMGNKTNDLAVLLPPGRSPLIVTGYFEN +PSFSED----------------- +>[subseq from] class A beta-lactamase n=1 Tax=Microbacterium barkeri TaxID=33917 RepID=UPI000377090E +----ADELAALEQEYDATVGVMAVDTGTGESV-SYGEDRRFGFASTIKAFAAAVFLQSVP +--GAARDEMVHWTAEEAAAHAPVTSQHVEDGLTYAQLAEAAVRVSDNAALNLIVDRIGGS +AALDDALAELGDATTEVVNDEPTLNTIEPGSTDDTTTAAAFTASLTRILDGSTLSAADAA +LLVDWMSDNRTGDTLIRSGAPAGWTVADKSGGAGP-IRNDIAVVTRPGQDPIIITVLTSR +NDPHADFDDTLVASAASITL--- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI0008FD0809 +----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNHS +--EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV +KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD +LLKQVMIENETGDSLIKAGVSDNYIVGDKSGQGTYATRNDLAFIYPDKHNPIILAIYTKQ +DDKDGQPDDKVIADAAEEAI--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SEB3_9BACT +-dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLHKLD +KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTIWTTPDATVQLLKKFYKNEILSKNSYD +FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. XS-30 TaxID=2604421 RepID=A0A5B9WJP2_9BACT +-dSLRSEIAAIAARSGGTIGAGIMNLDTRDTL-FFQNDPVYPMQSVFKFPIAMAILHQVD +EGKLKLDQKIYIDKKWMVPWSPLRDAFPDGNQTLAQLLEYMVSQSDNIACDFLIDLAGGE +AVINDYVHGLGVKEIAIVASEAKMATAWDVQFTNFCAPSAMVQLLDILNKGTALSKTSND +FLWDIMLKTSTGPKRLKGLLPEGVQVAHKTGTSGTRATNDAGIILLPNGQKLAVVVYVMN +AKSDEATREATIAQIAKAAFD-- +>[subseq from] Beta-lactamase n=1 Tax=Ferrimonas sp. IMCC35001 TaxID=2569538 RepID=A0A4U1B8Y6_9GAMM +---VGAAIEQVATKLAGRIGFAAQEIGGKDII-AFNGDETFAMASTYKVAIAAAVLDRVD +RGELRLDQMVNVTLDMMMIGDAALNTHPGLQLSIANLIEVMITESDNTATDISMGLAGGP +AAVTKYLRRLGISDFRVDRTTGEIIGDFEADPRDQATPHAMLKLLLAIDSGTAVSPKSRD +FLLGVMSRTRTGASRLKGLLPRGTPVANKTGTIG-GVANDVGYITLPDGRRFAVAVFTKS +SATPEPDRDRAIAEISRSLFDYf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium nakagawai TaxID=1241982 RepID=A0A448LJH9_9FLAO +-sSLEQRISAITKSKQATVGVSVLGFENQFKY-SQNGEKKLAMMSVFKFHVACAALDLVD +KGKLSLDQKIFIKKSELYNWSPYKEKHPEGNATLSEIIYYTVALSDNNLCDILIELVGGT +QAVQKFMNSKGVKDFQIKYTERGMANGWDSLFENYTTANSTVQLLKKFYDGKLLSKKSTD +YLMKIMLGTKTGTNKIIEQLPKGTPIAHKTGSSGKKAENDMGIITLPNGKHYAIAVYVSN +SKESEAENCKIISDISKAVWDNf +>[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas aveniformis TaxID=370977 RepID=UPI000688FC59 +-------------EVGGRIGVQAVR--NGRAT-SWRAHERFTYCSTFKLFLAAATLERVQ +AGDEQLDRPVAMTAADMVSHAPVTGQAVGGTLTIQALCQATVEVSDNPAANILIREMGGL +TAWRDWYRRIGDTVTNVDRLEPELNGV--GDARDTTTPGQFVANLQTLFADDVLSSMSRS +LLMSWLFASPSGPNRLRAGVPVGWEVAHKTGTSSRGPVNDIGLLIPPGGHPIHIAVFWQG +REDDFSLGEAAIAEATRRVVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI0013663FF8 +--QVTNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM +TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL +KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL +MFKQWLIASNTSNNHIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ +SQKNAKPNSKIVREVTKILLN-- +>[subseq from] Beta-lactamase n=2 Tax=Francisella tularensis TaxID=263 RepID=A0A0B3VEE7_FRATU +--QVTNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM +TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL +KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL +MFKQWLIASNTSNNHIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ +SQKNAKPNSKIVREVTKILLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE440B6 +-dKLDKAIEGIEQQAEGRLGVALMDLRDRKLW-SHRGSETFPMQSVFKLPLAVAVLQQVE +AGKFRLDQPITVTRKDFSLHSPLAKAFKGERYPLRELIRLAAGESDNTAADLLMRELGGP +QVVTKMLRDGGIQGMSVDRYERQFQPNALKDKRDASTPEASAQFLEAFAKGNWLRPAHAA +LLTQIITETKVGADRIKAGLPAGSRLAHRTGAGLNHATNDIGIATLPDGRRFVIVTYLAG +SRADAKEREAALADVARLAVS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0K0N4U2_ECOLX +------------------------------------------------------------ +----------XFKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQ--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Mucilaginibacter paludis DSM 18603 TaxID=714943 RepID=H1Y9U6_9SPHI +--ALHAKIDSIARDARGTVGFAMLNIESRDTL-SYHGNMHLPMQSVMKFPIAITVLHDID +EGQFTLNQLIHIDKSDLPKYSPLRDKYPEGNISISELLSYMVSLSDNNACDILLKTLGGP +EVVDQYMHSFGIKQIAVKASEFQMAQGWDVQFTNWVEPKTMVRLLDIATKPNFLSKASHD +YLWKIMEATSTGPNQIKDLLPVGTIVAHKTGRSGTNATNDIGLITLPNGKHLAIAIMITN +STADLTTRESVIARIAKAAYD-- +>[subseq from] class A beta-lactamase n=1 Tax=Chitinophaga TaxID=79328 RepID=UPI000DBA38D8 +-qTLRLQIAGIAGNISGKVGVYAEILETKDTV-SFNRDQHFPMQSVYKFPIAMAMLHQVD +QHKFRLDQPIHVTKDDLIGVSPVRDQHPEGNMPLGELIDYNIRASDGSACDVLLRLLGGT +AKANAYVHSLGVKQLAISTTEKVQVPSEMIQYKNWSTPMAMTQLLKIFYQEPVLSDSSKN +YLMHLMVTSRPGAKRLKGLLPAGTVVAHKTGTSWTRATNDVGIITLPNGHHLAITVFVSD +AKASEEEREGTIAKIAKAAYDHw +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. 8AT TaxID=2653134 RepID=A0A653T598_9FLAO +---LAQKVDSIVKGKKATVGVSVLGFEDGFKY-NKNADTKLPMLSVFKFHIAAAVLDLVD +KGKLSLDQKILIKKSDLLEWSPIREKYPNGNLPLSEIINYTVAWSDNNGCDVLLRLIGGT +QVVQKFMDSKGVKDFQIKNNEEQMHKGAKYLYENYTTANSLSQLYKKFYDGKILSEKSTK +FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN +STETDDVNCKMISDISKAVWDHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Variovorax sp. s2p11 TaxID=1367567 RepID=A0A0B5E9G5_9BURK +----------------------KLDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEA---------------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T1V8_9BACT +---LRNKIEQILSDKNAVVGVSIIGNNGKDTL-SLNGDKRFPMQSVFKFHIALAVLSEID +KGKLSLDQKIQISEDELLPWSPLRDENPNGGFTIEKLIQYTVSHSDNTACDVLIRLIGTP +KSVEEYIKKSGINDIQITFNEEDMQAKWENMFQNWTTPKAASETLKLFYENNLLSKNSYN +FFWKTNKETTTGKNRIRGQLPNETIVAHKTGWSGTAAVNNIGIVFLPNGQYFIISVFVSE +SKENFDMNEKIIAEIAKATYDFy +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. FH2 TaxID=1674291 RepID=A0A0J7ISR5_9FLAO +--ALEKKISNIIKDKKATVGVSVLDFENNFKY-NKNGEKKLPMQSVFKFHIAAAVLDFVD +KGRLSLDQKILLNKTNLLEWSPLRDKYPNGGIPLSEVIENTVAMSDNNGCDILLKLIGGT +QTVQKFMDSKGVTGFQIKFNEEAMHKDWNVQYENYSTTNSAVQVLKKFYAGKLLSKKSTD +YLLKIMLGTKTGLNKLVEQLPKNTPVARKTGASGTGAENEIAIVTLPNGQHYAIAVFVSN +STETDAINCKMISDISKSVWDYf +>[subseq from] Beta-lactamase n=1 Tax=Spirosoma sp. 48-14 TaxID=1895854 RepID=A0A1Q3WSW2_9BACT +--QFRTEIEQIAQEAQGRVGVAATLLETGESV-GVHENEQYPMQSVYKLPIGMAVLHQVD +QGKLALTQLVHVSQSDYISHSPIRDKFPQGAITLAELLRYAVSESDGSASDVLLRVVGGP +DVVMNYLQTLGVTGVMVLNTEREIGSDNAVQYRNWAKPDQLVALLKAVQAGKGLSITSHA +WLLHLLIDTQTGLQRLKGLLPAGTPVAHKTGTSWTAATNDVGILKLPNGRHIAIAVLVSD +AKADAKTREAVIARIAKVAWDYw +>[subseq from] Serine hydrolase n=1 Tax=Siphonobacter curvatus TaxID=2094562 RepID=A0A2S7IJA1_9BACT +-qRLQQELERMARLAKGKVGVCALHLESGREI-RMNANDRFPMASTMKVAVAVELLRKIE +KGELSYLTMTELKPSDLHPGSGTLETLFAKPLSLQNLMELMMVISDNSATDVLIRLAGGT +GAVQNRLKTLGIKGMSVDRTIIQLIATFDKDPRDTATPQAMVELLTQIYQAKAVSAASRD +TLLAIMERCRGGQGRLKGYLPPETVVAHKTGTMGASATDDVGIITLPGNGHIVIAVMVGA +SQAPSELREQTIAQISRSVYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma sp. 209 TaxID=1955701 RepID=UPI00098D1EC1 +-qRMERELERIARLGGGQVGVQAIHLESGQQI-SYNPQLKFPMASTVKVAIAVQLLQRIE +RGELSLTTMVDLKPSDLHPGSGTLTALFNKPLSVQNLLELMMVISDNSATDILLRLAGGP +EAVRNCLKSLNVQGMSVDRSIIELLAAFGTDPRDTSTPAAMVDLLAKIYQGKALKPESRD +VLLGVMERCRSGEARLRGFLPPNTVLAHKTGSLGATATDDVGYITLPDDGHIAIAVFIGP +STQPTAEREQTIAHMARAVYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma sp. HMF3257 TaxID=2183553 RepID=UPI0012F7CC22 +--RLRTEIEQLAQAAQGRVGVTATVLETGASV-NLNGDQQFPMQSVYKLPIGMAVLQQVD +QGKLALSQTVHVTPDEYISHSPLRDKYPTGAVSVAELLRYAVSESDGSASDVLLRLLGGA +KTVMASLKKLDITGIIVANTEKEIGSDNAVQYRNWATPTEVVALLRAVENGRNLSASSRT +LLLHLLTETETGLHRLKGLLPAGTVVAHKTGTSWTAATNDVGLITLPSGKHIAIAVFVSD +SKADQVIRERVIAQIAQVVWNHw +>[subseq from] Class A beta-lactamase n=1 Tax=Porphyrobacter sp. CACIAM 03H1 TaxID=2003315 RepID=A0A2Z2P1W3_9SPHN +---LAAELRIIEAAGDGTLGVEIHDTATGRSV-GINQDKRFGHASSFKFSLAALLLQRHA +AGAIDADRRVTWSEADMMHHAPFTRERIATGATLRELARATQITSDNPAANILLRELGGP +AALTAFWRSLGDEVSRLDRHEPEMNLVPTSEFRDTTTPAAMARTVAKIVYGDVLPEPQRA +ELKGWMIETDTGLKRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKGAPITFACYFRA +RQGMQPIGEQTLARVGRII---- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Novosphingobium TaxID=2644732 RepID=UPI00135B1F68 +--DAVDALRAIEARAGGRLGAYILDPARGSGV-GWRENERFAHCSSFKMSLAAMVLAGAE +RGEIDLDEVLRWSAQDLLSHSPVTSGAVDGGLPVKALAHATLVTSDNTAANVLLRRFGGP +VQLTHFWRSLGDTVSRLDRYEPELNQIPAGSEFDTTTPAAMAATVARLLLGDRLSPQGRG +TLKSWMIEVETGSDRLRSGFPADWISGDKTGTGGQQTYVDLAFGGPAKATPLIVACYLQT +ARDTDPLALAAMAEVGR------ +>[subseq from] Beta-lactamase n=1 Tax=Spirosoma sp. HMF3257 TaxID=2183553 RepID=A0A327NS46_9BACT +--RLRTEIEQLAQAAQGRVGVTATVLETGASV-NLNGDQQFPMQSVYKLPIGMAVLQQVD +QGKLALSQTVHVTPDEYISHSPLRDKYPTGAVSVAELLRYAVSESDGSASDVLLRLLGGA +KTVMASLKKLDITGIIVANTEKEIGSDNAVQYRNWATPTEVVALLRAVENGRNLSASSRT +LLLHLLTETETGLHRLKGLLPAGTVVAHKTGTSWTAATNDVGLITLPSGKHIAIAVFVSD +SKADQVIRERVIAQIAQVVWNHw +>[subseq from] Beta-lactamase class A n=2 Tax=Bosea sp. AK1 TaxID=2587160 RepID=A0A542B4Y7_9BRAD +-dKLDKAIEGIEQQAEGRLGVALMDLRDRKLW-SHRGSETFPMQSVFKLPLAVAVLQQVE +AGKFRLDQPITVTRKDFSLHSPLAKAFKGERYPLRELIRLAAGESDNTAADLLMREIGGP +QVVTKMLRDGGVQGMSVDRYERQFQPNALKDKRDASTPEASAQFLEAFAKGNWLRPAHAA +LLTQIITETKVGADRIKAGLPAGSRLAHRTGAGLNHATNDIGIATLPDGRRFVIVTYLAG +SRADAKEREAALADVARLAVS-- +>[subseq from] Uncharacterized protein n=1 Tax=Microbacterium sp. SZ1 TaxID=1849736 RepID=A0A2A4E5F2_9MICO +-----PQIRAIEADFEVAVGAVAIR-DDGRIV-DHDGDARMPYASTMKVFMAAALLATAS +PEERGTNVRWTPSQIDAAGYSPVTSEHLDDGLSLDALAEAAVRDSDNTAANLVMESLDGP +AAVQDFLRARGDTTTVVTAYEPELNVVVPGSDDNTSTPSALATSLKSLFDGDSLDPRSRD +TLLDWMSGNASGDALIRAAAPSGWIVADKSGGAG-GVRNDVAVVTTGSGERIYIAILTAK +TDPDAAYDDEVVEQVARVMLAEf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Pedobacter sp. eg TaxID=2201271 RepID=UPI000EB1E130 +-tTLQHKLDSIVKSKRADVGFSALFLPDQKNI-SVNGNKHYPMQSVYKFHLALTVLNLVD +NGKFSLQQKIRIKKSDLLAWSPLRDKYPEGNLPLAEILKYTVSQSDNNGCDILFRLIGGP +KSANDFIKKQGIKDINIVATEEEMHKDDQVQFSNWTTPNAANELLRKFLAGKILRKTTQN +FLMKIMEETSTGPGKIKGLLPQGTRVAHKTGSSGTAASNDIGIVSLPGGKKIIISAFVSM +SKENEAENDKIIAELTKAVYD-- +>[subseq from] Beta-lactamase n=1 Tax=Spirosoma sp. KCTC 42546 TaxID=2520506 RepID=A0A515A0J9_9BACT +-nSLRNQLEQIARTAQGRVGVTATVLETSETV-TLNGDQQFPMQSVYKMPIGMAVLQQVD +QTKLTLEQVVHVTPSEYVSHSPLRDKYPTGAVSVAELLRYAVSESDGSASDVLLRVLGGP +KVVMNYLHTLGINGIIVANTEKEIGSDNAVQYRNWAKPNEAVILLRAVQEGKGLSASSRT +LLLRLLTETETGLHRLKGLLPAGTIVAHKTGTSWTAATNDVGLITLPNGHHTAIAVFVSD +SKADQTTREGVIAKVAQAVWNYw +>[subseq from] class A beta-lactamase n=1 Tax=Microbacterium sp. SZ1 TaxID=1849736 RepID=UPI000BBC5EBF +-----PQIRAIEADFEVAVGAVAIR-DDGRIV-DHDGDARMPYASTMKVFMAAALLATAS +PEERGTNVRWTPSQIDAAGYSPVTSEHLDDGLSLDALAEAAVRDSDNTAANLVMESLDGP +AAVQDFLRARGDTTTVVTAYEPELNVVVPGSDDNTSTPSALATSLKSLFDGDSLDPRSRD +TLLDWMSGNASGDALIRAAAPSGWIVADKSGGAG-GVRNDVAVVTTGSGERIYIAILTAK +TDPDAAYDDEVVEQVARVMLAEf +>[subseq from] class A beta-lactamase n=1 Tax=Asaia prunellae TaxID=610245 RepID=UPI0011DCDA67 +---LAEIARHYEQKSGGRIGVHLFCPETGSAL-SWRGKERFLMCSSFKASLAACVLARCD +GDDDDLTHRLPFIDSDFRTWAPVAQKNRDAGLSLAALCAAAVTMSDNVCTNMLLRHIGGP +STLTKFWRESGDDVTRLDAYEPELNRPSADPQANTTSPVAMARTLHRLIHGTLLHPNSAA +LLRGWMTKCTTGTHRLRAGFPSDWVVGDKTGSNGKDIAADIAFASPESSKSVIIAAYTSG +GRPNETQFRKIFRDIGAL----- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Emticicia sp. CRIBPO TaxID=2683258 RepID=UPI001412548B +--ALRKNIQEILNTSKAKVGVAVLGLEDRYSL-TFYPKIHFPMQSTYKFPVALAILDRVD +KGKLKLDQKIHVSKSELHPWSPMREKYPEGNLPLSELLAFMVSQSDNNACDILFAIAGGP +KKVDQYVKALGVKQIAIAATEYEMHQGWEVQYTNWCEPWAMMQLLDLFHKRKLLKKPTHD +FLWKTMVETTTGPKKIKGLLPKGTLVAHKTGSSGTAASHDVGIVTLPDGKHFGIVVLVGD +SKETEEFREALVAKISKATWDYy +>[subseq from] Beta-lactamase n=1 Tax=Dyadobacter jejuensis TaxID=1082580 RepID=A0A316AA41_9BACT +-qDLREAISTIVEQAEGKVGVGVLNVQRSEPV-YWNENHRFPMQSVFKFPLALAVLDRVD +KGELDLQQVVPITRADLPPWSPIRDKYPSGDLTVSELLQYTVSQSDNNGCDLLFRLLGGP +ARVDAYIKKWVPEGIAIVADEAKMATAWEVQFGNYATPVAMSRLFQQFYAGQILSAGSTA +YLKQILLETNTCTACMKGLLPEGARVAHKTGRSATAATNDAGVLLLPNGQEVVVVVFVGD +SPADDRTREGIIAQVSRAVWDHy +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas koreensis TaxID=93064 RepID=UPI0013DFFDCF +--TLESAFALLARQTDGTVGVAVQRIGGGPVY-TLNAGQTFPMASTFKIAVAGAVLARID +RGDFKLDTMVTVDPAVWVQSAGIAEQHPGVALSVHNLLELMLTRSDNTATDVMVTQAGGP +AAVTAWLRKVGVTSQRIDADTARLIYPFNNDPRDASTPEAMVQLLAAIQSGKALSASSTK +ALIEIMERCITGEKRLKGLLPQNTVVAHKTGTLMS-IANDVGIVTMPDGSKFAIAVFVKS +DTKGVDTQERVIAEIARTAYDHy +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium greenlandense TaxID=345663 RepID=A0A101CI81_9FLAO +---LEQKINSITKDKNATVGISVLGFENGFRF-NKNSDKKLPMQSVFKFHIAAAVLDYVE +KGKLSLDQKIALNKSNLHEWSPLREKYPNGNVTLGEILEFTVAKSDNNGCDIMLKLLGGT +KTVQNFMNSNGVKNFQIKFNEEEMHKDWNVQYENYSTTQSAMDVLKKFYDGKLLSKKQTD +YLMQVMLSTSTGMNKIVEQLPKNTPVARKTGASGTGAENEIAIITLPNGKHYAIALFVSN +STESDATNCKMISDISKAVWDYf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7XXM3_9BACT +--TLESRLAALAAEAGGVAGVAILHVESGQRA-SLRGGERFCMASVYKLPIAIALLRSVD +RGRIALDQKVTYGARDLRPHSAIVDRAAGGSATVRELVEAMLIESDNTASDLVMGLLGGP +AAVTAELRAAGLGGIDVSRPEGQIALRFASDPRDTATPDAMATLLGRLQKGELLQPPRTA +LVLDLMTRATTGPDRLKGLLPKGTVVAHKTGTGGNSCSNDVGLLTLPDGSHLAVAAFVRT +SPRPLAARERAIARIGRAAYDRw +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=A0A3A0H0Y9_STAGA +-----KSIKDLEATYDTTIGVYGINTQDGKQI-EHRANERFAFASTYKAIASGILLNQLS +--PQDLNQKVTINKSDIVTYSPVTEKYIGKTMTLRQLIEASMLKSDNTANNKVIQAIGGV +NAFKSELRQLGDCISEPQRLEPDLNNYDPKKIADTTTPRAAATTLNYILTHSNMQKGNLQ +FLKELMIENETGDSLIKAGAAKDDIVGDKSGQGTYATRNDLAFIYPKGQKPIILAIYTKQ +SDKNAKPNDEVIAKTAEIAIKY- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=UPI000D1DE64A +-----KSIKDLEATYDTTIGVYGINTQDGKQI-EHRANERFAFASTYKAIASGILLNQLS +--PQDLNQKVTINKSDIVTYSPVTEKYIGKTMTLRQLIEASMLKSDNTANNKVIQAIGGV +NAFKSELRQLGDCVSEPQRLEPNLNNYDPKKIADTTTPRAAATTLNYILTHSNMHKGNLQ +FLKELMIENETGDSLIKAGAAKDDIVGDKSGQGTYATRNDLAFIYPKGQKPIILAIYTKQ +SDKNAKPNDEVIAKTAEIAIKY- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000D1F4002 +----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT +--EREINKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI +SSFKTALQHLGDHVSDPQRLEPKLNDYDPTNTADTTTPRAAAHTLNELLTSNQMDTKNLK +LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK +DDKEGTPDDKVIAKAAQIAIK-- +>[subseq from] Beta-lactamase n=1 Tax=Pedobacter alluvionis TaxID=475253 RepID=A0A497Y8Y4_9SPHI +-qDLKKAIETIAGKHAAKIGFAVADLQNGDTI-GFNGIAHYPMQSVYKFHLALAVLKQVD +EGKLTLDQQILVKAKDLLPWSPLRDKYPQGNIPLAEILGYTVSQSDNNGCDILFRLVGGP +AKVNQFIHGIGLKDVAIVATEEEMHLDEKVQFKNWSTSFSAVQLLKMFYDKKILSKSSGD +FLWDIMVKTVSGPNKIKGLLPKGTIVAHKTGSSGTTASNDIGIVALPNGKHFAIAVFVSM +TKEEEKVTDQIIAECSKATWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Microbacterium sp. 1.5R TaxID=1916917 RepID=UPI0011A1372C +------QIRAIEAEFAVTVGVVAIR-DDGRIV-EHDGDVRMPYASTVKVFIAAALLATAS +--PEERGTNVRWTASQIVAYSPVTSEHLGDGLSLDALAEAAVRDSDNTAANLVMESLGGP +AAVQDFLRARGDTTTVVTAYEPELNVVVPGGDDSTSTASALATSLKSLFDGDSPDTGSRE +TLLDWMSGNATGEALIRAAAPAGWIVADKSGGAG-GVRNDVAVVTTGSGERIYIAILTAK +TDPDAAYDDEVVEQVARIVLAEf +>[subseq from] Serine hydrolase n=1 Tax=Desulfobacteraceae bacterium TaxID=2049433 RepID=A0A3A4SL68_9DELT +-kDVSQKIEKLAEGLVGRIGVAAQEIGGDQVI-AVNGDETFAMASTYKVAIATTVLDRVD +KGELSLDQLVEVPQDMYVTVIALAETHPGVKLSVANLIEVMITDSDNTATDVCMGLAGGA +AAVTKNLRRLGITDFRVDRTTREILMDFEADPRDHATPLAMLKLLLAIDGGTAMSAESSK +FLLGVMSRTRTGAGRIKGLLPKGASVAHKTGTAG-GIANDVGYVTLPDGRRFAIAVFTNS +SKTSVADRDRAIAEVSRTLYDFy +>[subseq from] Class A extended-spectrum beta-lactamase PER-14 n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=A0A650A8W0_RAOOR +---LKEQIETIVTGKKATVGVAVWGPDDLEPL-LLNPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQSVTVNRAAVLQWSPMMKDHQGDEVAVQQLLQYSVSHTDNVACDLLFELVGGP +QALHAYIQSLGVKEAAVVANEAQMHADDQVQYQNWTSMKAAAQVLQKFEQKKQLSETSQA +LLWKWMVETTTGPQRLKGLLPAGTIVAHKTGTSGTAATNDAGVIMLPDGRPLLVAVFVKD +SAESERTNEAIIAQVAQAAYQ-- +>[subseq from] Beta-lactamase n=1 Tax=Solibacter usitatus (strain Ellin6076) TaxID=234267 RepID=Q025P5_SOLUE +---LSTHFADLARPAAGKVGASVLVIETGERA-GFHARDPFPMQSVYKFPIAMATLHLVD +TGKLKLDQPVPIAKAELAPHSPIRDQHPEGALSLREVIRFAVAESDGTASDVLLRLSGGP +SAVTAYLRGLGINGVIVATSELEMSRGPMVQYRNWATPDSMVDLLRAFHAGRGLSPAART +LLEDFMAQSTPGPKRLKGLLPPGTRVAHKTGTSGTRATNDVGIVTLPNGRHLAIAVFVSD +STASLDLREEAIAKIARAAWDAf +>[subseq from] Uncharacterized protein n=1 Tax=Agromyces sp. Leaf222 TaxID=1735688 RepID=A0A0Q4HDD8_9MICO +heRMSRDLRELERAASVTIGVHAVDHRAGRPVfRYRGADLFPMCSLFKVLAAAALVRDRG +YDEAYWTTPIPFAKADVVRDSIVLEALRPRRATPGQLADAALRYSDNTAGNLLLRELGGP +SAITAFAASLGAKRTRLDRWEPELNDAVPGDVRDTTTPDDIALLSTALLLDDAAGVLASS +RLREWMLRNTTSGARMRAGLAAPYELADKTGGGEYGVVNDAGVLWRAGRDPLTLVILTRT +DRPDATRNNEVVAEATRIVVG-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A075M8X1_ECOLX +------------------------------------------------------------ +-------QRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYF-- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Tolypothrix campylonemoides VB511288 TaxID=1245935 RepID=A0A0C2KX69_9CYAN +----QERLKNLDSAAQGKVGIGVLDLNSGQSW-FLNGKQRFPMQSVYKLPSAIAVLKQVD +EGKISLKQLVTITRQEFAPWSPIIKEVKGDRIPLRNVLEGSVGISDNTAADALVRLVGGT +KQVNAILGKLQIRNIRVDRLEQQLQPKYLTDPRDTATPEAMVDLLAKLNSNQLLSENSTA +LLLKIMTDSPTGQKRLKAGLPENWSIAHKTGTGANTATNDVGIATSPDGKRVAIAVFIAG +SKAPLEEREKVMSNIASRVVQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium xixisoli TaxID=1476462 RepID=A0A4R8I377_9FLAO +--ELRKELNQIISTKNATVGISLKGIENKDTL-SINGNMNMPMMSVFKFHIALAVLNEVD +RGKLALNQKIFIKKEDLKEWSPIREEFPNGNLTLDQLLRYTVSHSDNNGCDILLELIGGT +ETVQKFINKNGIKDFTIKMNEDQMRT-WENLYINTTTPIATTKLLEKFYNGKVLKKTTTK +YLYQIMVECSRGTTWMKAGLPAGTELAHRTGISGTNSMNDIGIIKLPNGKHFILSIYLKN +ITESREDTEKIIADITRATWNYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. K2R01-6 TaxID=2320861 RepID=A0A418WQC1_9SPHN +--AIEQQVTRLGQGSGGVVGVAAWRLDKGPRV-LVNADQAFPMASTFKVAVAAKIFDRVD +KGELRLEQMLDVPSDMIVPSEVIADRLIHPGLSIYNLLELMLTQSDNTATDVLTKAAGGP +AVVTAWLRGQGVTGQRVDRDTAGLLRVFDEDPRDTSTPTAMATLLTRIFSGKALSAQSTK +ALIGIMERCRTGGARLRGKLPPGTVVANKTGTIG-GTVNDTGVITLPGDGQIAIAVYVKK +SAAPMADRERAIAEIARSVHDFy +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga sancti TaxID=1004 RepID=A0A1K1PIW1_9BACT +--ALRKTIDSIATHSKSRIGVAALLLETGDTL-TYKGNDHYPMQSVYKFPISFAILHQVD +LGEYKLDQKITITNDDILPHSPIREAHPHGGMTIREISRLNIQESDGTACDVLLRLLGGT +KKTDDYIKSLGVKGINIATTEKEQQTNDTIQYRNWATPIAITQLYKVYFQSNILSKSSYD +VLWKDMTESHPGPKRIKGQLPAGTIVAHKTGTSGTAATNDTGIIILPNGKHLILTVFVSD +SKGSEAEREGWIAQISKAVYDHf +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. Leaf9 TaxID=1735674 RepID=A0A0Q4CPI1_9SPHN +----ATSFANVEQLHGGRLGIFALDTQTGRSL-AYRADERFKLMSSFKGLLSAMILLDVA +KGRGSLDAPVRYQPSDLIPASPVTQANVARGMSVGELCEAIMYRSDNTAANLLMRRAGGP +ARLTAFLRSIGDTVSRIDHYEGDLTGH--PLPADSTSPRAVTKAVRQIMLGTILPSFAQR +QWEGWMAGNVLGRTRLRAGFPANWVSGDRSGTGD-GICNDFAFARRPAAAPLLLSVYYAA +PGSELADQEAVLRKIARLVVQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Sphingomonadales bacterium EhC05 TaxID=1849171 RepID=A0A1B6Z548_9SPHN +-----SEIAEIEQNIGGRLGVGLIDGEGALIL-AHRGDERFALCSTFKAALASVLFAAHA +AGTVDMFAKFALKPADRVPYMPFVDKKLAAKVSLHQLAGAAVMTSDNAAANLILKATGGP +AEFTRFVRAQGDDVTRLDRIEPELNENAIGDPRDTTSPVAMARLIKKLALDDAALDIDKL +TLQNWMKASKTGASRIRAGLPKGWPVGNKTGTAAGGARNDIAIIWPAAAKPVTLTVYVDR +PMAPPEEVDAAMADVARIAA--- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium gregarium TaxID=456299 RepID=UPI0003F656DD +---LAEKINVIVKGKNATAGISVLNFENGFSY-HQNADKKLPMQSVFKFHIAAAVLDFVD +KGKLSLDQKVTLDASNLMEWSPLRDKYSGKNVALSEILEYTVAKSDNNGCDILLKLLGGT +ETVQKFMDSKGVKGFRIKYNEAEMHKDWNAQYENYTTAKSAVDVLKKFYDGKLLSKKSTD +YLMKVMFSTSTGKNKLIEQLPENTPVARKTGASGTGAENEIAIITLPDGRHYAIAVLVSN +STETDAVNCKMISDISKTVWDYf +>[subseq from] Beta-lactamase n=1 Tax=Runella sp. HYN0085 TaxID=2259595 RepID=A0A344TET7_9BACT +--SLRKKIQQIVSTKNAIVGVSIIGNDEKDTV-SLNGERHYPLQSVFKFHIALAVLSQID +KGKFSLDQKVEIQKKDLLPWSPLREENPNGGFPISKLIQYTVSQSDNVGCDALLRLLGGP +IVVEEYLKKNNIKDISIKLNEEKIQANWDLQFQNWTTPKAANEVLSKFYYNKLLSKKSYD +LIWKTMKGTETGKARLKGQLPKGTIVAHKTGSSGTAAVNDIGIIFLPNGKHFFISVFVTN +SKENEETNEKIIADIAKVAWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. EPR-157 TaxID=1813677 RepID=UPI000837ED51 +---VSTVIRNLEQRFDARVGVSAFDTETGATM-SYRGSERFGFASTLKAFAAAEFLRQTS +--TEDRDELVRWTRSDIDRYSPVTTENLDTGLTAAELAEAAVRESDNTALNLVLDRIGGP +EGLDDALELLGDATTEVVNYEPELNTITSGSIDDTTTADAFTESMTALQQTSYSTSSNRS +ILLDWMSGNKTGDPLVRAGAPAGWVVADKSGGAGP-IRNDIAVVTPPERSAVVITILTEK +NDPAAQFDNELVSETAAVVLH-- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium piperi TaxID=558152 RepID=A0A086AQQ0_9FLAO +htTLEQKIDSIINDKKATVGVSVLGIEDPLNY-NKNGEKKLPMQSVFKFHIAAAVLNLVD +MGKLSLDQKILVKKSDLLDWSPLREKYPNGNIPLSEIIDFTVAQSDNNGCDILLRLIDGT +NTVQKFMDTKGIKNFQIRFSEEEMHKDWNAQYQNYSSTNSIVQVLKKFYEGQLLSKKSTD +YLMQVMLGTKTGTNKLIEQLPKNTPVAHKTGSSGTGAENDMGIVTLPNGKHYAIAVFVSN +STEAEAVNCKIISDVSKAVWD-- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. YR221 TaxID=1500293 RepID=A0A1W1YZN5_9FLAO +---LGQKINAVTQGKNATVGVSVLDFDNKFRY-SKYGDQKFPMQSVFKFHIAAAILNYVD +QGKLSLNQKVLLDSSNLLEWSPLRDKYPNGNVPLSEILELTVARSDNNGCDIMLKLLGGP +QTVQKFMDSKGIKGFQIKYNEAEMHQNWNVQYENYSTPNSAVDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYAIAVFVSN +SMETDAVNCKMISDISKEVWDYf +>[subseq from] Beta-lactamase n=1 Tax=Pedobacter sp. RP-1-16 TaxID=2572196 RepID=A0A4V6WPQ1_9SPHI +--SLQEKLAQIIKGKKADVGVSVFFLGDRRSI-SVNGDQHYPMQSVYKFHLALAVLDQVD +KGKMALHQKIFVKKSDLLPWSPLREKYPNGNLPLSEIIRITISESDNNGCDILFRLVGGP +NKVHKYIVKLGIKDCAIAATEEEMHKDDKVQFTNWTTPKAANLLLEKFWNGQVLKKNTSA +FLMKAMEETVSGPNKIKGLLPSGTIVAHKTGYSGTAATNDIGIVRLPNGKRILISVFVSM +SKETEKVNDLIIAELARAAWD-- +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas koreensis TaxID=93064 RepID=A0A1L6J8L2_9SPHN +--TLESAFALLARQTDGTVGVAVQRIGGGPVY-TLNAGQTFPMASTFKIAVAGAVLARID +RGDFKLDTMVTVDPAVWVQSAGIAEQHPGVALSVHNLLELMLTRSDNTATDVMVTQAGGP +AAVTAWLRKVGVTSQRIDADTARLIYPFNNDPRDASTPEAMVQLLAAIQSGKALSASSTK +ALIEIMERCITGEKRLKGLLPQNTVVAHKTGTLMS-IANDVGIVTMPDGSKFAIAVFVKS +DTKGVDTQERVIAEIARTAYDHy +>[subseq from] Beta-lactamase n=1 Tax=Asaia platycodi SF2.1 TaxID=1382230 RepID=A0A060QHF4_9PROT +-hALSDIATRYEKISGGRLGVHIFCPENGTAL-SWRGEERFRMCSSFKASLAACVLARCD +RDEDDLTRRIAFRESDFKEWAPVAARNRDAGLSLAALCAGAVTMSDNICANMLLRHIGGP +AALTRFWRDSGDEITRLDAFEPELNRPSANPDDNTTSPVAMARTLHRLIHGTLLHPNSAA +LLRSWMINCTTGTQRLRAGLPAHWVVGDKTGNNGKDIAADIAFASPDAGKSVIIATYTAG +GTPDETQFCRVFHDIGAL----- +>[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia subsp. philomiragia ATCC 25015 TaxID=539329 RepID=C6YW16_9GAMM +---ISNHLHNLEKQYGGKIGVYTINRNDNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM +TDNNLLNKEVKISANQIIGYSPVTKKHINQTMTVSELSKAAI-QSDNTATNLLIEKLGGL +NNLNNFILSLHDHATKVAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILDKKHRL +LFKKWLLENDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMAIFYTQ +SQKDAKPNSKIIREVTKILLD-- +>[subseq from] Class A beta-lactamase n=2 Tax=Cryobacterium flavum TaxID=1424659 RepID=A0A4R8UZZ5_9MICO +--AFNRRIEDLEMQSGVTIAVTAVNLGTNRRV-QHRSTDLFPMCSLFKVIAVGALVSERG +YDEQYWNTPIPFTAADIVVNSPVASKLTTLTMTPDEMADAALRFSDNTAGNLLLREIGGP +KTIARVVGSFGATATRLDRIEPELNEGLPDDPRDTTTADDMVAVLRALLVDGGAGQLARS +KLHDWMLRNSTSSTRARAGLTGSYELADKTGAGGYGIVNDAGILWPDDTDPIALCILTRT +NDPNAKGNNEVIADTTRLLVS-- +>[subseq from] Class A beta-lactamase n=1 Tax=Mucilaginibacter xinganensis TaxID=1234841 RepID=A0A223P0F4_9SPHI +--GLRQQISDIIKPAKGIVGVSILNLESRDTL-SVNGDARLVLHSVMKFPIALTMLHWVD +SGKLTLDKMIHIKKKDLPKYSPLRDKYPNGNVSVSDLLSYMVSLSDNDACDILLKLIDGP +KTVQDYMLRLGIRGIAVRATEADMASSWELQYTNWCKPKEATLLLDKFYKGEILAKNTTA +FLYKILTETSTGPHRIKGLLPAATVVAHKTGTSPTNATNDVGIIELPNGKHLAISVFVCN +STDNEATREAVIAKIAKAAFDYy +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas koreensis TaxID=93064 RepID=UPI0013DF6909 +--TLESAFALLARQTDGTVGVAVQRIGGGPVY-TLNAGQTFPMASTFKIAVAGAVLARID +RGDFKLDTMVTVDPAVWVQSAGIAEQHPGVALSVHNLLELMLTRSDNTATDVMVTQTGGP +AAVTAWLRKVGVTSQRIDADTARLIYPFNNDPRDASTPEAMVQLLAAIQSGKALSASSTK +ALIEIMERCITGEKRLKGLLPQNTVVAHKTGTLMS-IANDVGIVTMPDGSKFAIAVFVKS +DTKGVDTQERVIAEIARTAYDHy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=J9V7T2_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGLAMGDSQRA +QLVTWLKGHTNGA----------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium piscicola TaxID=551459 RepID=A0A1N7N125_9FLAO +---LDKKITTIVKDKKATVGISVLGFENGFKY-SKNGEKKLPMQSVFKFHIAAAVLDLVD +KGKLSLNQKIVLTKDNVLEWSPLRDKYPNGGVSLNEILELTVAKSDNNGCDIMLELLGGP +KTVQDFFDSKAVKNFQIKYNEAEMHKDWNAQYKNYTTMNAAVDVLKKFYDGKLLSEKSTD +YLMKVMLSTSTGKNKLIEQLPKNTSIARKTGASGTGAENEIAIVTLPNGKHYAIAVFISN +SMESDEVNCKMISDISKVVWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Bosea robiniae TaxID=1036780 RepID=UPI000891C1B6 +-dKLDKAIEGIEQQAEGRLGVALMDLRDRKLW-SHRGSETFPMQSVFKLPLAVAVLQQVE +AGKFRLDQPITVTRKDFSLHSPLAKAFKGERYPLRELIRLAAGESDNTAADLLMREIGGP +QVVTKMLRDGGVTGLSIDRYERQFQPNALKDKRDASTPEASAQFLEAFAKGNWLRPAHAA +LLTQIITETKVGADRIKAGLPAGSRLAHRTGAGLNHATNDIGIATLPDGRRFVIVTYLAG +SRADAKEREAALADVARLAVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas koreensis TaxID=93064 RepID=UPI000834FFA4 +--KLESAFALLARQTDGTVGVAVQRIGGGPVY-TLNAGQTFPMASTFKIAVAGAVLARID +KGDFKLDTMVTVDPAVWVQSAGIAEQHPGVALSVHNLLELMLTRSDNTATDVMVTQAGGP +AAVTAWLRKVGVTSQRIDADTARLIYPFNNDPRDASTPEAMVQLLAVIQSGKALSASSTK +VLIDIMERCITGEKRLKGLLPQNTVVAHKTGTLMS-IANDVGIVTMPDGSKFAIAVFVKS +DTKGVDTQERVIAEIARTAYDHy +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium taeanense TaxID=311334 RepID=A0A1G8NAC6_9FLAO +---LDKKISSIIQDKKSTIGISVLGFENGFKY-NKNADKKLPMQSVFKFHIAATVLDYVD +KGKLSLDQKVLLDKSNLLEWSPLREKYPNGGIPLSEVLEYTVAKSDNNGCDILLKLLGGT +QTVQRFMDSKGLKGFQIKYNEAEMHKDWNNQYKNYSTASSATEVLKKFYDGKLLSKKSTD +YLMKVMFSTSTGKNKLIAQLPENTPVARKTGASGTGAENEIGIVTLPNGKHYAIAVFVSK +STESDVVNCKMISDISKSVWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000D1C34EE +----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKSIASGVLLNNYS +--EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV +KGFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQINDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKGGQPDDKVIADAAEEAI--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Haliea sp. TaxID=1932666 RepID=A0A519IZX4_9GAMM +--DFDATIRQIEADSGGRLGVAILDTQSLRLW-SHRAGERFPMCSTFKLLLAAQVLSRVD +QGREHLGREIAVQASDLVPYAPVTAPRVGGALTVAELCEAAVTLSDNVAANLLLRSAGGP +AALTAYARSLGDGLTRLDRIEPHLNEAAPGDLRDTTTPAAMLQTLQKIILGDALSPASRA +HITDWLRASKTGARS--------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0011551F34 +------------------------------------------------------VLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARGDEVSRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAA------- +>[subseq from] class A beta-lactamase n=1 Tax=Microbacterium sp. G1 TaxID=2615184 RepID=UPI00124B3940 +---VADELAALEQEYDATVGVMAVDTGTGESV-SYGEDRRFGFASTIKAFAAAVFLQSVP +--GAARDEIVHWTAEEAAAHAPVTSQHVEDGLTYAQLAEAAVRVSDNAALNLIVDRIGGS +AALDDALAELGDATTEVVNDEPTLNTIEPGSTDDTTTAAAFTASLTRILDGSTLSAADAA +LLVDWMSDNRTGDALIRSGAPAGWTVADKSGGAGP-IRNDIAVVTRPGQDPIIITVLTSR +NDPHADFDDTLVASAASITL--- +>[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. zg-578 TaxID=2663858 RepID=UPI0012B5EE91 +----DRRLAALEERYDARVGVSLLDTGDGAAY-SYRGDQRFGFASSVKVLVAAELLRRTG +--SAERAELVRWTQDDVDAYSPVTEAFVGRGLPLLRLAEAAVRESDNTATNLVLERLDGP +AGLTRGLRGRGDTTTVVADDEPGLNEVSPGSPANTTTPDAFVADLRALLGPEWLTDADRR +LLLGWMSGNPGGDPLIRAGAPAGWRVAQKSGGAGP-VRNDVAVLTPPDGAPVLLAVLTTR +LDPTAPYDDALVADAAEVAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. Leaf296 TaxID=1736327 RepID=UPI0009EB90EC +--AVDAALSALEAEYDARIGLVAVDSEDERTV-EHRADERFRFASSIKALAAGALLARTE +--PSDLERVVTW--SDVVDHSPVTGPATATGLPLGEVAEAAVRLSDNTAHNVVLQELGGP +AGLQEALRALGDDVTRVDRVEPELNRVSPE-GLDTGTARSLAADLRTLLLGDPLDSADRA +QLRDWMSGNATGDALVRASAPDGWSVLDKSGGAG-GLRNDLAVVERPGAAPIVIAVLTER +TDPTLPYDDALVARAASVALE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Agromyces sp. CF514 TaxID=1881031 RepID=A0A1I6JI17_9MICO +---IARELAALERETSVTVGVVARTHGDRRAF-RYRADSVFPMCSLFKTLAAAALVRERG +YDEVYWSTPIPFA--DAVVDSPILGPKAPGRATPEEIADAALRYSDNTAGNLLLGELGGP +QAITAFAASLGATRTRLDRWEPDLNAAVPGDARDTTTPDDIAALYEALLLDDAAGVLAGA +RLREWMLRNTTSNARMRAGLTPPYELADKTGGGEYGVVNDAGVLWREGRAPVTLVILTRT +DRPDAVRNNEVVARATRIVI--- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium gleum TaxID=250 RepID=Q8VT49_9FLAO +---LEQKINSIIKNKKATVGVSVLGFENGFKY-DKNGDKKLPMQSVFKFHIAAAVLNAVD +QGKLSLDQKIMLNQSNLLEWSPLRDKYPAGNIPLSEVIEYTVAKSDNNGCDILLRLLGGT +QVVQKFMDSKGVKGFQIKYNEEDMHKDWNVQYENYSTTKSAADVLKKLYDGKLLSKKSTD +YLMKVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN +SMETDAVNCRMISDISKEVWEYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=unknown TaxID=N/A RepID=UPI0014385E6A +--SLNTDIKSLLDSKQATVGVSIWDQNANPIV-EINADNQLPMQSVFKFHLAVAVLHQVD +QGKWSLADKITITPDDLDNWSPIRKKYPTGALTLAQIIKYTVAVSDNVGCDVLIGMLGGP +KVLEQYLHQAGIKDVAIKYNEEMMQQVWQRQFDNWTTANGANQALSKLYDEQLLSATSHR +FLWDVMKSSKTGKNKIRAGVPEGTVVAHKTGYSGKHAHNDIGIVFLPNGSHYYISVLVSD +SRESSDDSQKIIADISQLAWMHf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Planctomycetes bacterium Poly41 TaxID=2528016 RepID=A0A5C6E232_9BACT +-kDVSQKIEKLSQGLVGRIGVAAQEIGGDQVI-AVNGDETFAMASTYKVAIATTVLDRVD +KGELRLDQLVEVPPDMYVTVIALAETFPHPGLSVANLIEVMITESDNTATDVCMELAGGA +AAVTKNLHRLGITDFRVDRTTRQILMDFEADPRDHATPLAMLQLLLAIDGGTAMSAESSK +FLLGVMSRTRTGADRIKGLLPKGTSVAHKTGTAG-GIANDVGYVTLPDGRRFAIAVFTNS +SKTPVADRDRAIAEVGRTLYDFy +>[subseq from] Beta-lactamase n=1 Tax=Dyadobacter sp. SG02 TaxID=1855291 RepID=A0A1H6W0L9_9BACT +-aKLKSDIETISKQAQGIVGVGIMNLKTQETL-LINQDHKFPMQSTFKFPLAMAMLDLVD +KGKYKLDQKIHVTQSQLEKHSPMRDEYEGKDITVGELLSYSVSESDNNACDILFGLAGGT +KIVNDYIHSLGVKDIAIVATEKEMATGWNTQYDNFARPSAYLQLLEIVYLRKKFSKSSQE +FLWKIMVDGPTGLKRIKGELPKGTVVAHKTGTSGTAATNDVGIVKLPNGNDIAIVVFVSD +ATANLDTRERVIAQIAKAAWNYy +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. CCH4-E10 TaxID=1768758 RepID=UPI00082E4F4D +-sALEQKINSIIKDKNATVGISVLGFENGFKY-NKNADKKLPMQSVFKFHIAAAVLDYVD +QGKLSLDHKILLDKTNLLEWSPLRDKYQQGNVPLSEILEYTVAKSDNNGCDIMLKLLGGP +ETVQKFMNSKGVKGFQIKFNEADMHKDWNAQYQNYSTAASATEVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGKNKLIEQLPENTPVARKTGASGTGAENEIAVVTLPNGKHYAIAVFVSN +STETDAVNCKMISDISKSAWDYf +>[subseq from] Beta-lactamase n=1 Tax=Pedobacter steynii TaxID=430522 RepID=A0A1D7QMH8_9SPHI +---LQQKMDSIIHSKKADVGVSVLFLEDHKIV-SVNGDKHYPMQSVYKFHLALAVLNQVD +QGKLALDQKILVKKSDLLPWSPLRDQYPEGNLRLSEILKYTVSQSDNNGCDILFRLIGGT +KKAHQFIVKQGIKDISITGTEEEMHKDDQVQFRNWTTPKAANELLKKFWEGKVLKKPTAD +FLMKVMEETVTGTGKIKGLLPQGTVVAHKTGNSGTNASNDIGIVTLPNGKKMLISAFVSM +SKENDKEVDKIIAELSKAAYD-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Rudanella lutea TaxID=451374 RepID=UPI0003721717 +---LRTEIQRIVAGKKAVVGVSIIANDGKDTL-SLNGDRRLPLQSVFKLHIGLAVLAQVD +KGRFTLDQTVEVRKDDLLPWSPLRDENPNGGFSIAKLIQYAVSQSDNVACDVLIRLLGSP +KAVETYIKENGVEEIAIRFAEKEMQAEWDNMFQNWTTPKAASKTLQTFYDGKRLSKRSYD +FIWQTLRETNTGVNRLKGRLPAGTVVAHKTGSSGTAATNDIGLLFLPNGEPVIISVFVAD +SQENEATNEKLIADIAKATYDFy +>[subseq from] Uncharacterized protein n=1 Tax=Pelomonas sp. Root1237 TaxID=1736434 RepID=A0A0Q6XEN8_9BURK +----AADFAALERRVQGRIGFFAIDTGSGRVM-AHRADERFATASTFKILLAARVAQGVE +AGRWGWNDAVPLRESERVPHSPAFDRLLPRGATLAELVQGIVVESDNPCANVLLRHCDSP +AGLTTWLRQQGDAVTRLDRFETELNENAPGDPRDTSTPRAFARTLQHLLLGPGLKRANQA +RLWADLQASRTGLKRLRAGVPASWRVIDKTGSGARGAVNDVALVFPPGGSPWVVVAFQSD +SKASSDELSTVHADAMRGLVRAw +>[subseq from] Beta-lactamase class A n=2 Tax=Microcoleus sp. PCC 7113 TaxID=1173027 RepID=K9WDF5_9CYAN +-tQLQEQLNNLDSSAQGDVGIGVLDLDTGERW-FRNGKQRFPMQSVFKLPLGIVVLKLVD +EGKLSLNQTVTITREQFVPWSPILKEIKGDRFTVQYLLQRAVGDSDNTAADALVRLVGGP +EQVTANLERLNLRDIRVDRLEQQLQPRYLVDPRDTATPEGMIDLLALLQSRQLLSEDSTA +LLLKIMTDSPTGQKRLKAGLPQGWSIAHKTGTGEDVATNDVGLISSPSGRNIAIAVFIAG +SKAPLEQRESVMSAVAAAVVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A539DEI8_9PROT +-------LELLEQKVGGRLGVFMLDTDTGLAQ-THRGKEPFGMCSTFKLPLAGVVLREAD +AGRLDLEERIAFTQADMVPHAPVTSQHLAQGMTVEALAETAQKTSDNVAANLLIKRLGGP +EGVTAKVREIYAHGFRLDRYETQMNFVPPGEVRDTATPEGMGLIVSNLIATRGLTPASRG +TLIQWMHDTRTGLKRIRAGLPREWPAGDKTGTADPNKVNDVAAIWPTTGGPVIVVAFYEA +PGGTRNQDQEVLAEVGKLA---- +>[subseq from] Uncharacterized protein n=1 Tax=Erythrobacter sp. HI0063 TaxID=1822240 RepID=A0A165R6F5_9SPHN +--EIYARLAELAERAEGTLGASVLDPGSGAFA-SWNGDRRFPHCSSFKVSLAAMVLDLVA +RGQIDGKRLLHWSEADLMWVSPFTTRRLGQGATFLELARATQVTSDNTAANVLLRELGGP +EALTAWWRALGDGTSRLDRTEPALNRVLPGEVHDTTTPDAMARTMATILYGDALAPSVSE +RLASWMAKTETGSRRVRADLPDRWRAGDKTGTAMGSAYVDIGFVVPDGRGPLTFATYYMV +DADMDPQAEALLAEVGRTIAAVf +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2W6S710_9SPHN +-----AQLRTLERSAQGRLGAFVLDTATGRHF-GWRADERFCHCSTFKLSLAAMALRESD +AGRLDLAEPLAIGRTDVVAYSPVVEDNLAKGLPILILAQAVQITSDNAAANILLRRLGGP +DALTRFWRDIGDETSRLDGYEPAINVIPPGTQENSTTPRAMAMTVQSLVVGDVLRPASRD +LLRGWMAATQSGLDRIRAALPRNWQGFDKTGTGMGNKVNDLAVLVPPDGSPLIVTGYFEN +PSDVRPQDEAVLKRLGEIAV--- +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas koreensis TaxID=93064 RepID=A0A430G415_9SPHN +--TLESAFALLARQTDGTVGVAVQRIGGGPVY-TLNAGQTFPMASTFKIAVAGAVLARID +RGDFKLDTMVTVDPAVWVQSAGIAEQHPGVALSVHNLLELMLTRSDNTATDVMVTQTGGP +AAVTAWLRKVGVTSQRIDADTARLIYPFNNDPRDASTPEAMVQLLAAIQSGKALSASSTK +ALIEIMERCITGEKRLKGLLPQNTVVAHKTGTLMS-IANDVGIVTMPDGSKFAIAVFVKS +DTKGVDTQERVIAEIARTAYDHy +>[subseq from] Beta-lactamase n=1 Tax=Rheinheimera sp. A13L TaxID=506534 RepID=F7NRS8_9GAMM +---LKEQIETIVTGKKATVGVAVWGPDDLEPL-LVNPFEKFPMQSVFKLHLALLVLHQVD +QGKLELSLSVAVKRAEVLQWAPMMKDYQGDEVTIEQLLQYSVSHSDNVACDLLFELIGGP +AALHAYIQFVGIAETDVVANEAQMHADDQVQYQNWTSMKAAARILKKFEQKELLSETSQA +LLWKWMVETTTGPERLKGLLPADAVVAHKTGTSGTAATNDIGVIMLPDGRPLLVAVFVKD +SAESNKTNEAIIAQVAQAAYQ-- +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas koreensis TaxID=93064 RepID=A0A2M8WBT0_9SPHN +--KLESAFALLARQTDGTVGVAVQRIGGGPVY-TLNAGQTFPMASTFKIAVAGAVLARID +KGDFKLDTMVTVDPAVWVQSAGIAEQHPGVALSVHNLLELMLTRSDNTATDVMVTQAGGP +AAVTAWLRKVGVTSQRIDADTARLIYPFNNDPRDASTPEAMVQLLAVIQSGKALSASSTK +VLIDIMERCITGEKRLKGLLPQNTVVAHKTGTLMS-IANDVGIVTMPDGSKFAIAVFVKS +DTKGVDTQERVIAEIARTAYDHy +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. URHD0057 TaxID=1380389 RepID=UPI00048FD646 +-qALQSELSHLAKPAEGVVGIAAWRLDAGPRV-LVNADQGFPMASTFKVAVAGKILADVD +GGKLSLDQLVPVPHAMMVESEGLASTFRYDGVSVRNLLELMLTVSDNTATDVLTKLAGGP +TAVTAWVRSQGIEGLRVDRDTAGLIRKFDKDPKDTATPLAMGTLLQRIFTGKALSSASTK +LLTGIMERNTTGKARIRARLPEDTVVAEKTGTIG-GSVNNVGLVTLPDGGKVIMAIFIKE +SRQPFEVRERVIADVARALYDYf +>[subseq from] Beta-lactamase n=2 Tax=Phenylobacterium zucineum TaxID=284016 RepID=B4RHE4_PHEZH +--RLNEEMAELARRAPGALGVGLMNLESGEAF-TLAGDRRFPMQSVFKMLLGAAVLSEAD +AGRLPLDERHSLTEEQLSPYSPIAEAWPARRYTARELLTAAVSVSDNTAADVLMKRIGGP +GAVDAWLQARRIEEIRVDRYERQLQTAYLADPRDTATPRGMLEFLSRLNANELLSPMSTL +LLLQLMTDTPTGARRLKAGLPDGAILAHKTGTARTDAINDVGIFTLPDKRSYALAVFLAG +STLDRAAREAIFADAARIAV--- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus edaphicus TaxID=1955013 RepID=A0A2C6U8F1_9STAP +-nSTNNDIEKIEKKYGANVGMYALNTQNGKEL-SFNENKRFAYASTLKTISSAMLLEQTP +--YNKLDKKIHINKDDIVPYSPVLEKYIGKEITLKKLIEATMLFSDNTANNKIIDELGGY +GQVKTKLIDLGDTTTHPSRKEPDLNFYSPKDKRDTSTPLAYGKTLKKLIADGDLSKANKD +FLLNLMFKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVAFVYPDGQKPIILVIFTNK +DRKYGKPNDKIVSEVAEIVLK-- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. S30B TaxID=2561925 RepID=A0A4Y9RCE2_9CAUL +------DLSALETRPGDRLGFAVHDLASGRRL-AWRGEERFVYCSTFKMYLAAATLLRVQ +AGEERLDRAIAITRADMINHAPTTEPAVGSTLTVEQLMKGTVELSDNPAANILIREMGGL +DALRAFYLGLGDDSTTVDRLEPEMNRL--DGDKDTIQPLQSAANIRRLLVDTPLNADSKA +RLMRWLIDTPTGTNRIKAGAPPGWTVAHKTGTGGYGPVNDIGLIQTPGRPPIVIAAYFHG +APGSDAAGEAAIAEATRRAL--- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium rhizosphaerae TaxID=395937 RepID=A0A3D9CWR1_9FLAO +---LEQKINTVTQGKNATVGVSVLDFDNKFRY-SKYGDQKFPMQSVFKFHIAAAILNFVD +QGKLSLNQKVLLDSSNLLEWSPLRDKYPNGNVPLSEILELTVARSDNNGCDIMLKLLGGP +QTVQKFMDSKGIKGFQIKYNEAEMHQNWNVQYENYSTPNSAVDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYAIAVFVSN +SMETDAVNCKMISDISKEVWDYf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WRV6_9BACT +--------EEIARVSNGPVGAAAMEVETGEVV-ALNGKQRFPMQSVYKFPIGMAVLHQVD +TGVLKLDQKVRVKPTDLAPRSPLRDLHARGALTVRELLTFMMVDSDSSASDVLLATVSGP +QQATKYLRELGIEGINVATSEKQMATDDQVQYQNWSTPEAMLGLLKILQEGRSMSPASRD +LLLELMRKTWTFPTRIKGLLPAGTVVAHKTGSSGTRATNDVGLITLPNGHHLAVAVFVSD +TKVDEKTRDAVIAKIARAAWDCw +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. YR203 TaxID=1500291 RepID=A0A1M5G786_9FLAO +-eNLRKEIKQIISTKNATVGISVKGIEDKDTL-SINGNLQMPMMSVFKFHIALTVLNQVD +KGKLKLNQKIFVKKEDLHAWSPMRDEFPDGNLTLDEILRYTVSHSDNNGCDLLLRMLGGT +ETVQQFINKQGIKDFTIKVNEQEMAS-WDNLYLNTTTPLATTELLEKFYKGKVLKKETTK +YLYQIMAETSRGITWLKAGLPEGTEIAHRTGISGRAAMNDVGIIKLPNGKHCILSLYLKN +ITEERTETEKTMADIAKAVWNYy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium vrystaatense TaxID=307480 RepID=UPI0004E7289B +-eNLRKEIKQIISTKNATVGISVKGIEDKDTL-SINGNLQMPMMSVFKFHIALTVLNQVD +KGKLKLNQKIFVKKEDLHAWSPMRDEFPDGNLTLDEILRYTVSHSDNNGCDLLLRMLGGT +ETVQQFINKQGIKDFTIKVNEQEMAS-WDNLYLNTTTPLATTELLEKFYKGKVLKKETTK +YLYQIMAQTSRGITWLKAGLPEGTEIAHRTGISGRAAMNDVGIIKLPNGKHCILSLYLKN +ITEERTETEKTMADIAKAVWNYy +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. PAMC 26617 TaxID=1112216 RepID=UPI0002881974 +----AAALAALERHHGGRLGVHALDMHTGRTL-GYRADESFKLMSSFKGLLAALVLSNVS +KGRDSLQSPVRYGPSDLMAASPVTQANVARGMTVRELCEAIMLRSDNAAANLLMRRSGGP +AGLTAFLRSIGDRVTRIDTYEGHLTDH--PLPADSSTPRAVTETVRRILCGPVLPIAGRR +LWEGWMAGNIVGRARLRASFPANWIAGDRTGTGD-GICNDFAFARRPGIAPLLLSAYYTA +PGSELPDQEAVLRAVSRLVV--- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Planctomycetes bacterium Pla52n TaxID=2528005 RepID=A0A5C6B6A8_9BACT +-kDVSQKIEKLSQGLVGRIGVAAQEIGGDQVI-AVNGDETFAMASTYKVAIATTVLDRVD +KGELSLDQLVEVPPDMYVTGEALAETFPHPGLSVANLIEVMITESDNTATDVCMELAGGA +AAVTKNLRRLGITDFRVDRTTREILMDFEADPRDHATPLAMLQLLLAIDGGAAMSAESSA +FLLGVMSRTRTGAGRIKGMLPKGTPVAHKTGTVG-GIANDVGYVTLPDGRRFAIAVFTNS +SETPVVDRDRAIAEVGRTLYDFy +>[subseq from] HOA-1 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=C8C0L4_9ZZZZ +-qNLKRDITKIIQSKNALVAVSVMNSKGKTEV-NINGNKKVPMLSVFKFHIALAVLDLVD +RGILDLEQNIFVKKSELLEWSPIRDKYPNGNIPLREIIEYTVSQSDNNGCDILLRLIGGV +DTVQKFIESKGIKDFAIKYNEEEMNKNGKSIYSNYTTANASSRLLQKFYNGEIISESSRD +FLFRIMYETSTGADRLISLLPPDVIVAHKTGTSGQAATNDVGIIILPDDEYYTISVFVIN +SKENTSTNEKIIADISKTVWDYy +>[subseq from] Class A beta-lactamase n=1 Tax=Altererythrobacter sp. Ery12 TaxID=2306996 RepID=A0A419R341_9SPHN +--RLTAKLRLIEVGSGGTLGVMLLNTADGQTI-GHNSGERFAMCSTFKASLAALALDRAA +KGALDLDKVLYWRESDLQSYAPFAKERLVTGATIRELARAAQVLSDNTAANLVLGAVGGP +SALTQFWRSLGDDVSRLDNVEPLLNVVLPGRVENTTTPVAMARTLAKILFRGGVAPQAAQ +TLQQWMRETQTGTKKVRAGLPAEWVAGDKTGFSGQGVSADIGFAIPVDDAPIVFATYHRA +TTPPSPMADAAMAQVGGII---- +>[subseq from] Uncharacterized protein n=1 Tax=Sphingomonas sp. Leaf339 TaxID=1736343 RepID=A0A0Q6K7B3_9SPHN +--------------------WATLDKATGRFS-GVNVNDRMPMCSTFKWLLVACVLARTD +RGLERLSQRISFGPDDLLGYAPTVRAALTAALSIKDLCEAAVTVSDNSAANLLLPVVGGP +EGLTAWLRRAGDPITRLDRNEPALNRVPPGDPRDTTNAAAMLGTLDRLLFGAVLSRGSRH +RLTDWLLACKTGADRLPAGLPAGWRAGHKTGTYTRNAAGDVGLLLPPSGKPILIVAYVAG +SRQPQPVVDRWFASLARDAV--- +>[subseq from] Beta-lactamase n=1 Tax=Pedobacter sp. KBW06 TaxID=2153359 RepID=A0A3N7D035_9SPHI +--PLQQKLDSIVSTKKADVGFSVMYLENQKIV-SLNGDKHYPMQSVYKFHLALAVLNQVD +QGKLKLDQKIFVKKSDLLQWSPLREKYLNGNLPLSEILKYTVSESDNNGCDILFRLIGGT +GKADQFIKKQGIKEISITGTEEEMHKDDQVQFRNWTTPKAANNLLKKFLEGKVLKKTTED +FLMKIMEETVTGPGKIKGLLPKGTLVAHKTGNSGTAASNDIGIVTLPNGKKMLISAFVSM +SKESDQENDKIIAALTKAAFE-- +>[subseq from] Beta-lactamase n=1 Tax=Rheinheimera sp. YQF-1 TaxID=2499626 RepID=A0A437JKY7_9GAMM +--QLKEQIESIVANKSATVGVAVWGPNDLEPL-LLSPFEKFPMQSVFKLHLALLVLEQID +AGKLALNQSVAVKRKEVLQWAPMMKEHQGDEVTVEQLLRYSVSHSDNVACDLLFELVGGP +QALQAYVHSLGIREVAIVANEAEMHADDQIQYQNWTSMKAAALVLKQVEQKQLLSPTAQA +LLWKWMVETTTGPQRLKGLLPVDTEVAHKTGYSGTAATNDVGIIVLPDGRPLLVAVFVKD +SSESTKTNEAIIAQIAQAAYQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter sediminis TaxID=1689985 RepID=UPI001325E300 +---LAAKLRIIEAAAGGTLGVSIRNTATGQTV-GYKADQRFGHCSSFKMSLAALVLKLDQ +DGTVNAQERIRWTRGDLMPVSPFTTSRVDKGATLLELAEATQKTSDNAAANFLLGRLGGP +ERLTRFWRDIGDEASRLDRTEPALNNVPPGEVRDTTTPHAMALTNERILFGDVLAAERRA +LLRQWMEETETGARRVRAGLPKDWNAGDKTGTSTGGLYVDIGFAVPPGGDANTFAAYYRS +PKGTDPVSENVLRQVGEVLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Francisella sp. SYW-9 TaxID=2610888 RepID=UPI00123C90BF +---ISNDIHKIEKHYGGKVGVYTINRNNWHNF-THNETFYFPICSVYKFLVVGAILKESM +TDKNLLNEKIRISKNQLVGYTPITKKYVGREMTVRELSKASI-LSDNTATNLLIYKLGGL +KKLDSFILSLNDHATKITELEPKVNNVNISNNLNKTTPKIITRDLNKIAFHDILDKKHRI +LFKKWLRENNTGSNRIAAELPKGWKIGDKTGTCDYGSTNDVAIVWPNNSRAIVMSILYTQ +PIKNAEPKDKVIQEVAKLLFDNf +>[subseq from] Class A beta-lactamase n=1 Tax=Rubrivivax sp. TaxID=50259 RepID=A0A520BZY8_9BURK +---TSPDFAALERSVQGRLGFFALDTGSGRTL-AHRADERFSTASTFKILLAARVAQGVE +GGRWAWEDELPLHKSERVPHSPAFDRLLAARATLGELVQGIVVESDNPCANILLRHCDSP +AGLTMWLRQQGDEVTRLDRWELDLNENAPGDLRDTSTPRAFAGTLRRLLLGDGLTRPSQA +RLWADLQASQTGLKRLRAGVPASWRVIDKTGTGYRGAVNDVALVFPPDGSPWVVVALQSD +SRASTDDLSAVHAEAMRQLVRAw +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. FP211-J200 TaxID=1792309 RepID=A0A177LGT0_9FLAO +-dELRKELSKIITTKNATVGVSIKGIENKDTL-SINGNMNMPMMSVFKFHIALAVLNEVD +KGKLNLKQKIFIKKEDLKEWSPIREEFPNGNLTIDQLLRYTVSHSDNNGCDILLKLIGGI +EAVQKLINKNGIKDFTIKVNEEQMRT-WENLYINTTTPIATTELLEKFYKGKVLKKATTK +YLYQIMVECSRGITWIKAGLPEGTELAHRTGISGTNAMNDIGIIKLPNGNHFILSVYLKN +ITESREDTEKIIADITKATWNYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Cellulophaga sp. Hel_I_12 TaxID=1249972 RepID=UPI000647F2F1 +---LRSKIEQIVSDKNAVVGVSIMGNKVKDTI-SLHGDRRFPMQSVFKFHIALAVLSEVD +KGKLSLDQKIEINKNELLPWSPLRDENPNGGFTIERLIQYTVSHSDNTACDVLIRLIGTP +KTVEEYIKKNSIKDIQITFNEQDMQAKWGNMFENWTTPKAASETLKIFYENNLLSKTSHD +FFWKTNKETTTGNNRIKGQLPEGVIVAHKTGWSGTGAVNNIGIVFLPNGEYFIISVFVTE +SKESFDTNEKIIADIAKATYDFy +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WT06_9BACT +--RLQEQLNNLDSSAQGDVGIGVLDLDTGERW-FRNGKQRFPMQSVFKLPVGIVVLKLVD +EGKLSLNQTVTITREQFVPWSPILKEIKGDRFTVQYLLQRAVGDSDNTAADALVRLVGGP +EQVTANLGKLNLRDIRVDRLEQQLQPRYLTDPRDTATPEGMIDLLAKLQSRQLLSEDSTA +LLLKIMTDSPTGQQRLKAGLPPGWSIAHKTGTGAEVATNDVGLISSPTGKRIAIAVFIAG +SKAPLEQRESVMSAVASAVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. MK52 TaxID=2711156 RepID=UPI0013EA86DC +--ATSEALAAIERRAGGRLGAYILDPTTGRGT-GWRADDYFAQCSAFKLSLAAMILAGAE +RGLIDLNETLHWTEADLLSHSPVTRPATKTGLTVEALARGTLVTSDNPAANILLRRFGGP +EALTRFWRSIGDRMSRLDRTEPALNDVPPGSRLDSTTPRAMAQTAATLLLGPALSPASRE +TLKSWMRESATGLDRLRAGFPAGWDAGDKTGTWTRRIYVDVAFGGPAGAVPLIVAAYHET +RAGESGASAGVLAEVGRLAA--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sanxanigenens TaxID=397260 RepID=A0A2W5A2Z0_9SPHN +-qALSTQILTLEKQIQGRVGVAFRLVETGEGG-AVAGGERFPMASTYKVAIAGALLTLVD +KGQVSLDQMVSVTQRDFDQTGEVADRLIHPGLSVANMMELMLTQSNNSATDKMLELAGGP +AAVTTWLRANGIADMQVDRSVNDVLNAFEKDPRDTSAPTAMVDLLAKLLAGSLLKPESRT +FLIGVMERCETGQARLKGLLPQGTIVAHKTGTLG-GALNDVGMITLPGGGHLLIAVYTKS +SSLPGPQRERAIAEISRSLFDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=UPI00063D3582 +-kDLRNKIHEIVSTKNATVGVSLKGIEDKDTL-SINGNKNTPLMSVFKFHIALAVLNQVD +KGKLKLDQTFFIKKEELLPWSPIRDEYPQGNLTLDQLLRYTVSHSDNNGCDILLNILGGT +QTVQKFINQQGIKDFTIKVNEQQMSS-FDKFYLNTTTPLATTALLEKFYNGKVLKKETTK +YLYRIMVETSRGLTWMKAGLPEGTELAHRTGISNRAAMNDVGIVTLPNGKHYILSVYLKN +ITEEMKDTEKIIADISRAVWEYy +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma lacussanchae TaxID=1884249 RepID=UPI001109FE48 +-qRMERELERIARLGGGQVGVQAIHLESGQQI-SYNPQLKFPMASTVKVAIAVQLLQRIE +RGELSLMTMVDLKPSDLHPGSGTLTALFNKPLSVQNLLELMMVISDNSATDILLRLAGGP +EAVRNCLKSLNVQGMSVDRSIIELLAAFGTDPRDTSTPAAMVDLLAKIYQGKALKPESRD +VLLGVMERCRSGEARLRGFLPPNTVLAHKTGSLGATATDDVGYITLPDDGHIAIAVFIGP +STQPTAEREQTIAHMARAVYDYf +>[subseq from] Beta-lactamase n=4 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A077LCP2_ACIBA +---LKEQIESIVIEKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDQVPVQQLLQYSVSHSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQVAQAAYQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A3B8LE97_9PLAN +--RLAARIKPLVSRHQGQVAIVVRHLDSGREV-SWQPDRPMPTASLIKLAVMVEVYRQVD +DDRVDLDDRLKLTADDAVPGSGVLRKYFTTGLTLRDAVRLMIAVSDNTATNLVLDHI-GL +ESTNRTMSRLGHPNTRIHAKVFRRETSIDPERSGSTTASETADLLEAIRSGRAVSKRASR +QMLEHLRACES-TERIPRYLPEGTVVAHKTGSVSR-VRTDAGIIESPTG-PIVVCVLTAE +NQSAENAASRLIADISREAWLHf +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A3D2U0F2_9PLAN +--RLAARIKPLVSRHQGQVAIVVRHLDSGREV-SWQPDRPMPTASLIKLAVMVEVYRQVD +DDRVDLDDRLKLTADDAVPGSGVLRKYFTTGLTLRDAVRLMIAVSDNTATNLVLDHI-GL +ESTNRTMSRLGHPNTRIHAKVFRRETSIDPERSGSTTASETADLLEAIRSGRAVSKRASR +QMLEHLRACES-TERIPRYLPEGTVVAHKTGSVSR-VRTDAGIIESPTG-PIVVCVLTAE +NQSAENAASRLIADISREAWLHf +>[subseq from] Beta-lactamase n=1 Tax=Xanthomonadaceae bacterium SCN 69-123 TaxID=1660170 RepID=A0A1E4L0D4_9GAMM +--EAQSRLAALEAKAGGRLGVFVLDTGSGLGL-AHRGGERFGLCSTFKLPLAAVILREHA +AGRLDGHAPIALASTPTVPHAPAVEAARAAGLSALELARATQTTSDNVAANLLLDLLGGP +ARFTALLRGLGDEVTRLDRYETEMNRVGPDELRDTSTPQAMARLTARLFGPGLLDASSQR +VLAHWMVETRTGLQRLRAGLPADWRAGDKTGTALSNRHNDVAVTWPPQRPPVVIAGYYEA +DGVMRAEDDAVLAEVGGLV---- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium scophthalmum TaxID=59733 RepID=A0A1N6IEU6_9FLAO +---LAQKVDSIIKGKKATVGVSVLGFEDGFKY-NKNATTKLPMLSVFKFHIAAAVLDLVD +KGKLSLDQKILIKKSDLLEWSPIREKYPNGNLSLSEIINYTVAWSDNNGCDVLLRLIGGT +QVVQKFMDSKGVKDFQIKHNEEQMHKGAKYLYENYTTTNSLSQLYKKFYDGKILSEKSTK +FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN +STETDEVNCKMISDISKAVWDHf +>[subseq from] Beta-lactamase n=1 Tax=Caulobacter mirabilis TaxID=69666 RepID=A0A2D2AVK1_9CAUL +---LDKEIAVIADSVPAELEVAVQNLEGGEMW-AWNGQKAFPLQSVFKMVLGAAVLAEVD +AGRLALDDQITLTEADISPYSPVADAWPETEYTVRELLEKAVGDSDNTAADVLMKRIGGP +GAVTAWLRAKRIKEFRVDRYERELQPDYLADPRDTATASGVLNFLRQLSAGELLKPASTQ +LLLKIMTDSPTGEERLKAGLPPGATIAHKSATAATDATNDVGVVTLKDGRRYAVVVFLAA +SSQDDPTRDAAIAEAMRVIVK-- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. OV705 TaxID=1500289 RepID=UPI0006472102 +---LGQKINAVTQGKNATVGVSVLDFDNKFRY-SKYGDQKFPMQSVFKFHIAAAILNFVD +QGKLSLNQKVLLDSSNLLEWSPLRDKYPNGNVPLSEILELTVARSDNNGCDIMLKLLGGP +QTVQKFMDSKGIKGFQIKYNEAEMHQNWNVQYENYSTPNSAVDVLKKFYNGKLLSKKSTD +YLMKVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYAIAVFVSN +SMETDAVNCKMISDISKEVWDYf +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium nematophagum TaxID=2305228 RepID=A0A3M7TI83_9FLAO +---LDKRINSIIKDKKATIGLSVLGFENGFKY-HKNGEKRFPMQSVFKFHIAAAVLHAVD +QGTLSLHQKIFLKKSDLLEWSPLRDKYPNGNVPLSEIIDYTVALSDNNGCDLLLRLIGGT +QTVQKFMDSKGVKGFQIKYNEEAMHKDWKYQYENYSTPNSATQLLKKFYDGQLLSKESTE +YLMKVMLGTKTGLNKMIEQLPKNTPVARKTGASGTGAENEIGIVTLPNGNHYSITLFVSN +SIETDSVNCKIISDISKVVWDYf +>[subseq from] Beta-lactamase class A n=2 Tax=Pseudoxanthomonas indica TaxID=428993 RepID=A0A1T5KC02_9GAMM +--ALQLELDRFAAKFDGTVGLYALDLRTGRSA-VLNPADAFPMASTVKIPVAVHILSLVD +EGRLDLHRQVQLQEGDLYPGGPM-DTHLTPGITIRDLLHMMLTVSDNNATDILIRLGGGA +AAVNQRMQTLGVQGVRVDRYIWEMLSLYHQDPRDTSTPQGMAALLKLIWQGKALTPASTE +VLKAILLDCRTGQARLKGMLPDGTPVAHKTGTVGE-VINDVGVMTLPDGGDIIITVFLKS +GE-SDQARDRVIAQMARSVYDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Elizabethkingia sp. YR191 TaxID=2135666 RepID=A0A2T5RUW7_9FLAO +---LDSKINAIVKDKKATVGVSVLGFENAFAY-NKNGNEKLPMQSVFKFHIASAVLDLVD +KGTLSLDQKILVKKEDLLEWSPLRDKYPAGNVPLSEIIEYTVALSDNNGCDFLLRLIGGM +EAVQKFMNGKGVKGFQIKYNEEDMHKDWNAQYENYSTPNSAVQVLKKFYNGKLLSKTSTD +YLMKVMLGTKTGLNKMVEQLPKDTPVARKTGSSGTGAENEIGIITLPNGNHYALAVFVVN +SMESDTVNCKMISDISKAVWDGf +>[subseq from] class A beta-lactamase n=1 Tax=Asaia TaxID=91914 RepID=UPI001269204A +---------RYEKISGGRLGVHIFCPENGTAL-SWRGEERFRMCSSFKASLAACVLARCD +RDEDDLTRRIAFRESDFKEWAPVAARNRDAGLSLAALCAGAVTMSDNICANMLLRHIGGP +AALTRFWRDSGDEITRLDAFEPELNRPSANPDDNTTSPVAMARTLHRLIHGTLLHPNSAA +LLRSWMINCTTGTQRLRAGLPAHWVVGDKTGNNGKDIAADIAFASPDAGKSVIIATYTAG +GTPDETQFCRVFHDIGAL----- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR477 TaxID=1500295 RepID=UPI0006485C4B +---LEQKINSILKNKKATVGVSVLGFENGFTY-DKNADKKLPMQSVFKFHIAAAVLDAVD +KGKLSLDQKIKLDSSNLLEWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLRLLGGT +QTVQKFMDSQGVKGFQIKYNEEEMHKDWNVQYQNYSTTKSAVDVLKKFYDGKLLSKKSTD +YLMKVLWSTSTGMNKMVEQLPKNTPVARKTGSSGTGAENEIGIITLPNGKHYALAVFVSN +STETDAVNCKVISDISREVWEYf +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium formosense TaxID=236814 RepID=A0A085Z102_9FLAO +---LDQKISSIIKDKKATVGVSVLGFEDGFKY-DKNANKKLPTLSVFKFHIACAVLDLVD +QGKLSLNQKVVLKESELLPWSPIKEKYPTGDLTLDEIIDYTVALSDNNGCDKLLKMIGGT +QTVQKFMDSKGVKGFQIKVNEDEMHKDWKNQYKNYSTTKSAVTLLKNFDAGKILSKKSTD +YLMKIMLGTKTGMNKLVEQLPKNTPVAHKTGASGTVAENDMGIVTLPNGKHYAIAVFVNN +STETDVVNCKMISDISKIVWDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Spirosoma panaciterrae TaxID=496058 RepID=UPI0012F8899C +-dQLRSQIEQIARDAQGRVGVAATLLETGESV-GFHEMEQFPMQSVYKLPIGMAVLHQID +QKKLALTQVVHVTQSDYIAHSPIRDKFPQGVIPLSELLRYAISESDGSASDVLLRMVGGS +QVVMSYLKTLNVTEMMVLNTELEIGSDNAVQYRNWAKPAQAASLLRAVQEGRGLSKTSHA +FLLHLLTDTQTGLQRLKGLLPSGTTVAHKTGTSWTAATNDVGIITLPNGRHIALAVFVSD +AKADAKTREAVIARIAKVAWDYw +>[subseq from] Beta-lactamase n=1 Tax=Runella sp. TaxID=1960881 RepID=A0A3C0UYR3_9BACT +---LRQRLQRVAATTQGMLGVGIVDLSNGDTV-SVNGQGRFAMQSVYKFHLALAVLSEVD +KGKWALEQKIKVTKKDLLPWSPLREKYPNGELPLREILEYTVAQSDNNGCDILFRLVGGT +KVVDKYIKSIGINEVNIVGTEEEMHADDRVQFDNWSSPRSAAKLLVVFDQKKILSKNSWE +FLWNTLVSTTTGPRKLKGVLPQGTIVAHKTGYSGQGATNDIGIVQLPNGKRFAIAVFLNN +TTLPEAECDRAIAEAAKVAWDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia sp. ESBL41bB15_13_1E TaxID=1535126 RepID=A0A076V9Z9_9ESCH +------------------------------------------------------------ +---NLLNQRVEIKKSDLDNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILV----- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SCP7_9BACT +-dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLVKLD +KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTYWTTPDATVQLLKKFYKNEILSKNSYD +FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] Class A beta-lactamase n=1 Tax=Halieaceae bacterium GH4-78 TaxID=2547392 RepID=A0A4R5LR31_9GAMM +---VAAALDALTRGLIGYIGVAAEDMTTGKQV-FLNGEEPFPMASTYKVAIAVTLLAKVD +AGELSLTDMIELNDDEWVVSDIIASNFIHPGLSVANVMEVMITHSDNTATNVALRLAGGP +EAVNRQLEKLGISGMHVDRTTSDYSRAFEADPLDKSTPRAMLSLLTALYQGKTVSEESTA +FLLGIMSRTVTGPGRLRGLLPRKTPVAHKTGTLG-GVANDVGYITLPDGRRFAVVVFTRG +SHTLPSDRDRAIAEVARTLFDYf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000CEC91F8 +----------------------ALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVILTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga arvensicola TaxID=29529 RepID=A0A1I0SA55_9BACT +-qTLRRQIAAIAGNISGKVGVYAEILETKDTV-SFNRDQRFPMQSVYKFPIAMAMLHAVD +QQKFRLDQLIHVTKEDLIGVSPVRDLHPEGNIPLSDLIDYNIRSSDGSACDVLLRLLGGT +ANANAYVHSLGVKQIAIATTEKVQVPSEMIQYQNWSTPAAMTQLLRIFYQEPVLSDSSHR +YLMHLLTTSGPGAKRLKGLLPAGTPVAHKTGTSWTRATNDVGIITMPNGQHVAITVFVSD +AKASEAEREGTIAKIAKAVYDHw +>[subseq from] Serine hydrolase n=1 Tax=Stenotrophomonas sp. ATCM1_4 TaxID=2259330 RepID=A0A4R4ICQ9_9GAMM +----QAEAQRLASLLGGELGAAIVHLESGRSV-YINGDRPFPMASTMKVPVAVHILALVD +EGTLSLQQQVTLKADDIYPMGGPMDLHLSAGITVRDLLHMMITVSDNNATDILIRLGGGT +AAVDARMRALGIDGLRVDRYIWELLAAWNADPRDTSTARAMTLLLEKTWKGQVLSPASLD +VLQAIMRDTRTGTARLPGMLPRDTPVAHKTGTVGD-VINDVGVITLPGGGHAVISVFVQS +RA-SSQERDAAIAQLARAAHDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Cronobacter malonaticus TaxID=413503 RepID=A0A649UI66_9ENTR +--ETLVKVKDAEDQLGARVVYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +------------------------------------------------------------ +----------------------- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium daeguense TaxID=412438 RepID=UPI0004148762 +---LAQKINSIIKNKKATVGVSVLGFENGFTY-NKNADKKLPMQSVFKFHIAVAVLDLVD +KEKLSLDQKILLDKSNLLEWSPLRDKYPNGNVPLSEILELTVAKSDNNGCDILLKLIGGT +QTVQKFMDSKGVKGFQIKHNEEDMHKDWKVQYENYSTTQSAVDVMKKFYDGKLISKKSTD +YLMKIMLSTSTGLNKLVEQLPKNTPVARKTGASGTGAENEIAIVTLPNGKHYAIAVFVTN +SMETDAVNCKIISDISKTAWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000D1EB684 +----ANEFDQLEKENSTTVGVYGINTESGKEI-KHLSDERFGYASTFKAIASGVLLNNYT +--EKEINKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI +SSFKAALQHLGDHVSDPQRLEPNLNNYDPTNTADTTTPRAAAHTLNELLTSNQMDTKNLN +LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK +DDKEGTPDDKVIAKAAQIAIK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. Leaf404 TaxID=1736366 RepID=A0A0Q5ZQW2_9FLAO +---LDKKINAVVKDKKATVGISVLGFENGFKY-SKNAEKKLPMQSVFKFHIAAAVLDYVD +KGKLSLDQKVLLTKDNLMQWSPLRDKYPNGGVPLSEILELTVAQSDNSGCDILLGLLGGP +KTVQQFFDSKNVKNFQIISGEAEMHKDWKVQYKNYSTTNAAVDALKKFYDGKLLSEKSTE +YLMKVMLSTSTGKNKLIEQLPKNTPVARKTGSSGTGAENEIAIVTLPNGKHYAIAVFVSN +STESSEVNCKMISDISKVVWDYf +>[subseq from] Beta-lactamase class A n=2 Tax=Mucilaginibacter sp. OK098 TaxID=1855297 RepID=A0A1M7P419_9SPHI +---LRQQIKDVIKPAKGIVGVSILGLESRDTL-SVNGDARLVMHSVMKFPIALTVLHWVD +SGKLTLSQLIHIKKKDLPKYSPLRDKYPDGNVSVGDLLSYMVSLSDNDACDILLKVIDGP +KTVQDYMLHIGIRGIAVRASEADMASSWELQYTNWCKPFEMTILLDKFYKGEILAKPTTE +FLYKILTETTTGPHRIKGLLPAGTVVAHKTGTSPTSATNDVGIITLPNGKHLAISVFVCN +STDDETTRDAVIAKISKAAFDFy +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. RU33C TaxID=1907398 RepID=A0A1N7AB37_9FLAO +-sALDQKINSIIKDKKATIGVSVLSFESNFKY-SKNGDKKLPLLSVFKFHLASTVLDMAD +KGKFSTDQKFLIKKSDLLEWSPLREKYPEGNLSLGEIIKYTVAQSDNNTCDFLLRLIGGP +KVVQQFMDSKGVKDLQIKYTEDDMHKDWKNQYGNESSTNSTVALLKKFYDGKLLSKKSTD +FLMQIMLATTTGTNKIVEQLPKRTPVAHKTGSSRTVAENDMGIITLPNGKHYAIAVFVSN +STETERVNTRMVSDISKIVWDNf +>[subseq from] Beta-lactamase n=1 Tax=Pedobacter sp. RP-3-8 TaxID=2530454 RepID=A0A4R0MIG2_9SPHI +--SLQEKLAQIIKGKKADVGVSVFFLGDRRSI-SVNGDQHYPMQSVYKFHLALAVLDQVD +KGKMALHQKIFVKKSDLLPWSPLREKYPNGNLPLSEIIRITISESDNNGCDILFRLVGGP +NKVHKYIAKLDIKDCAIAATEEEMHKDDKVQFTNWTTPKAANLLLEKFWNGQVLKKNTSA +FLMKAMEETVSGPNKIKGLLPSGTIVAHKTGYSGTAATNDIGIVRLPNGKRILISVFVSM +SKETEKVNDLIIAELARAAWD-- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium gleum TaxID=250 RepID=UPI00103FDAC8 +---LEQKINSIIKNKKATVGVSVLGFENGFKY-DKNGDKKLPMQSVFKFHIAAAVLNAVD +QGKLSLDQKIMLNPSNLLEWSPLRDKYPAGNIPLSEVIEYTVAKSDNNGCDILLRLLGGT +QVVQKFMDSKGVKGFQIKYNEEDMHNDWNVQYENYSTTKSAADVLKKLYDGKLLSKKSTD +YLMKVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN +SMETDAVNCRMISDISKEVWEYf +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. G0162 TaxID=2487063 RepID=A0A3G6SAN1_9FLAO +-sSLEQKISAITKNKQATVGVSVLGFENQFKY-SQNGDKKLAMMSVFKFHVACAALDLVD +KGKLSLDQKVFIKKSELYNWSPFKTKYPEGNVTLYEIIDYTVALSDNNLCDILIELVGGT +QAVQKFMNSKGVKDFQIKHSERGMANGWDSLFENYTTTNSTVQLLKKFYDGKLLSKKSTD +DLMQIMLGTQTGANKIVEQLPKGTPVAHKTGSSSTIAENDMGIITLPNGKHYAIAVYVSN +SKESEAENCRIISDISKAVWDNf +>[subseq from] Beta-lactamase n=1 Tax=Francisella tularensis subsp. mediasiatica TaxID=135248 RepID=A0A4Q7HFE3_FRATU +--QVTNDIQNIEKKYGGKIGVYTINRNDWNNF-AVNASFYFPICSTYKFLVVGAILKQSM +TDNKLLNQKIKISKNQIVEYSPITRRHINQIMTVKQLCQASMQ-GDNTATNILIEKLGGL +KNLNKFNLSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL +MFKQWLIASNTSNNRIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ +SQKNAKPNSKIVREVTKILLN-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium frigidisoli TaxID=1125876 RepID=A0A1I3D866_9FLAO +-eDLESQINKIIAGKNATVGVSILGIDKPFVL-NMNGEKHLPMQSVFKFHIALAVLNLVD +EGKLDLIQKILVKKTDLLEWSPIREKYPNGNLTLAEIIKYTVAQSDNNGCDILLKLIGGT +KTVQGFINSKGVKDFQIKFNEEEMHQDWKAQYENYSSTNSIVKLLKDFHGGKIVSKSSTD +FLMKIMIGTSTGTNKLIAFLPENIIIAHKTGSSGTGAENDMGIVTLPNGNHYAICVFVSN +SKETEEVNCKMIADISKLTFDHf +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF47462 +----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS +--IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP +SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE +LLVDWMKRNTTGDKLIRAGVPKGWEVAD-------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Sulfitobacter sp. JL08 TaxID=2070369 RepID=A0A345RGP3_9RHOB +--SVGAAIEQIVSGLAGRIGFAAQEIGGDEVI-SFNGDETFAMASTYKVAIATAVLDRVD +RGELSLDQLVEVPNEMFVTVVALAETFPHGGLSVANLIEVMITESDNTATDVNMGLAGGP +EAVTENLRRLGITDFRVDRLTAEILRDFEADPRDHTTPLAMLQLLLAIDGGTAMSPESRE +FLLGVMSRTRSGPGRIKGLMPMGTPVAHKTGTVG-GIANDVGYVTLPDGRRFAIAVYTNS +SETSTSDRERAIAEISRMVFDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Tolypothrix bouteillei VB521301 TaxID=1479485 RepID=A0A0C1QSY6_9CYAN +------------SAAQGNVGIGVLDLNTGKSW-FRNGKQRFPMQSVYKVPIAIAVLKRVD +EGKLGLNQSVTVTRQDFAPWSPMAQEFKGNSFTVQDLLERSVGISDNTAADVLVRLVGGT +GQVNAILSRLKIRDVRVDRLERQLQSKYLTDPRDTATPEGIIDLLVKLQSNQLLSKKSTA +LLLKIMTDSPTGAKRLKAGLPNNWSIAHKTGSGPGTATNDVGVISSSNGKRVAIAVFIAG +SKAPVEAREKVMSDVASAVVK-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Mucilaginibacter gotjawali TaxID=1550579 RepID=A0A0X8X9D8_9SPHI +--ALRSRIEELSKPVKGIVGVSILNTETGDTL-SYNGKARLVLHSVMKFPIALTVMHLVD +SGVYTLSQVMHIPKRDLVKHSPMRDKYPKGVLPLSEIVKYMVAESDNNACDFLLKTIGGT +KTVQDYMLHIGIKGIAIRASEADMASMWELQYTNWCKPVEMTTLLDRFYRGKILAKSTTD +TLYKIMTETTTGPNRLKGLLPSGTVVAHKTGTSPTNATNDVGIITLPNGKHLVISVFVCN +STNDEATREGVISKIAKAAFDYy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium arthrosphaerae TaxID=651561 RepID=UPI000F4E9783 +-kDLKNKIHEIISAKNATVGVSLKGIEDQDTL-SINGNKKTPLMSVFKFHIALAVLNQVD +KGKLKLDQKFFIKKEELLPWSPIRDQYPKGNLTLDQLLRYTVSHSDNNGCDILLNIIGGT +AVVQKFINRQGIKDFTIKVNEQQMSS-FDKFYLNTTTPLATTELLEKFYNGKVLKKETTK +YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISDRAAMNDVGIVKLPDGKHYILSVYLKN +INEEMADTEKIIADISRTVWEYy +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas phyllosphaerae TaxID=257003 RepID=UPI0003B4E9F8 +----AARLRALERSAGGRLGAFVLDTGSGRHF-GWRADERFCHCSTFKLSLAALALREGD +AGRLDPAAMLAFGQADLVDHSPVVEAHLAAGLPVLALAEAVQVTSDNAAANVLMRRLGGS +AAVTRFWREIGDEISRLDGYEPTINEIPPGTTQNSTTPRAMAETVRRIVLGDVLATDSRE +RLRGWMAATRSGLGRIRAGIPAGWRGLDKTGTGMGNKTNDLAVLLPPGGAPLIVTGYFET +PSDVRPQDEAALKALGRLAIE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0N9HLN6_9BACT +-dSLRKQINEIVSTKKAVVGVAIVGGDGKDQV-VINGEKHFPLQSVFKFHIALLMLAEID +KGKFSLDQKIEIPKKDLLPYSPIRDKYPEGVLTIAEILEYTVSVSDNVGCDVLLRLLGGP +QAVEDYFTKNKFKDIAIKINEETQQANWDMQFQNWTTPKAANEVLSAFYYKKLLSQKSYD +FVWKTMRETSTGVKRIKGQLPAETVVAHKTGTSGTNAVNDIGVIFLPNGQHFFISVFVTD +SKEDADANEKIIADIAKAAWDHf +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. FH1 TaxID=1233951 RepID=A0A085B8L7_9FLAO +--ELRKKLNQIISTKNATVGISLKGMENKDTL-SINGNINMPMMSVFKFHIALAVLNEVD +KGKLALNQKVFIKKEDLKEWSPIREEFPNGNLTIDQLLRYTVSHSDNNGCDILLKLIGGT +KTVQKFINKIGIKDFTIKMNEDQMRT-WENLYINTTTPIATTKLLDKFYNGKVLKKATTK +YLYQIMVECSRGTTWMKAGLPDGTELAHRTGISGTNAMNDIGIVKLPNGKHFFISIYLKN +ITEPREDTEKIIADITKATWNYf +>[subseq from] Serine hydrolase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A355YG33_9GAMM +---LQWELERLVAPFDGKVGAYVLDLRSGRRA-QVNGDAGFPMASTVKVPVAVHILALVD +EGRLDLRQQVVLQAADIYPGGPIDTHLTAGSITVRDLLHMMLTVSDNNATDILIRLGGGP +AAVDARMRALGIDGIRVDRYIWEMLALYNADPRDTSTPAGMAALLLRIWEGRALRPDTTA +VLKAILLDCRTGQARLKGMLPDATPVAHKTGTVDE-VINDVGVIVLPGGGEVVVAVYLVS +GA-SDQARDRMIAQVARAAYDYf +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium lactis TaxID=1241981 RepID=A0A3G6RT29_9FLAO +-sTLDQKINSIIKDKKATVGVSVLGFENNFKY-SKNGDKKLPLLSVFKFHLASTVLDMVD +KGKFSADQKFLMKKTDLLEWSPLREKYPDGNLSLEEILTYTVAQSDNNTCDFLLRLIGGP +QTVQNFMNSKGVKNLQIKYNEDDMHRDWKNQYGNSGTTNSSVELLKKFYDGKLISKKSTD +LLMQIMIGTTTGTNKIVEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVNN +STETEKVNTRMVSDISKIVWDNf +>[subseq from] Beta-lactamase n=1 Tax=Flavobacterium sp. 316 TaxID=1603293 RepID=A0A0D6TR83_9FLAO +---LRQKIQKIVATKNATVGISIIGNNAKDTL-SINGDKHLPMQSVYKFPIALAVLSEVD +KGKLSLNQKINITKEDLHQWSPIREKYPNGTLSLSEVIKYSVSDSDNIGCDILLKLLGGT +KKVEDYFYSINFKNISIKATEEEMHKEWNVQFQNWITPKAASELLELFYYKKLLSKESHN +FIWKVMSETWTGNKRLKGKLPIGTIVAHKTGTSDTNAVNDIGIVFTKNGHFFIISIFVTN +SKESAETNEKIIADIAKLTWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma sp. I-24 TaxID=2666025 RepID=UPI00138E8ABB +--SLRNQIEQIAGTAQGRVGVAAMLLETGESV-ALLGDQRFPMQSVYKMPIGMAVLRLVD +QGKLTLDQKVRVETTEYVSHSPMRDQFPKGTVSVSELLRYSVSESDGSASDVLMRLAGGP +KSIMAYFKSLGIKDIIIANTEKEIGGDNAVQYRNWAKPTEVVGLLRLFQQGRGLSKSSRA +LLLRLMTETETGLHRLKGQLPAETVVAHKTGTSWTAATNDIGLITLPTGQHIALAVFVSD +SKADEKTREAVIAQIALATWDFw +>[subseq from] class A beta-lactamase n=2 Tax=Haloactinobacterium sp. HY164 TaxID=2675754 RepID=UPI0012B7F991 +------ALVRLEEESGVRIGAVGIS--AAARV-DHRAEEAFPMCSLFKVLAVAALLRERA +YDDAYWAEPIPFGPADLVEDSPVTSATTTWAMSPTALADAALRFSDNTAGNLLLAELGGP +EAITTFAADLGAANTRLDRWEPELNEATPGDLRDTSTPSDIALLYRALLLEDRAGALAGA +RLRDWMLRNTTSAARIRAGLDGDVELADKTGAGSYGVVNDAGVLWTGGPDPVTLVILTRT +DDPAAVNDNEVVAEATRIIMS-- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E7NKA6_9PLAN +--RLAARIKPLVSRHQGQVAIVVRHLDSGREM-SWQPDRPMPTASLIKLAVMVEVYRQVD +DDRVDLDDRLKLTADDTVPGSGVLRKYFTTGLTLRDAVRLMIAVSDNTATNLVLDHI-GL +ESTNRTMSRLGHPNTRIHAKVFRRETSIDPERSGSTTASETADLLEAIRSGRAVSKRASR +QMLEHLRACES-TERIPRYLPEGTVVAHKTGSVSR-VRTDAGIIESPTG-PIVVCVLTSE +NQSAENAASRLIADISREAWLHf +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. EPR-157 TaxID=1813677 RepID=A0A161VQY2_9NOCA +--------RNLEQRFDARVGVSAFDTETGATM-SYRGSERFGFASTLKAFAAAEFLRQTS +--TEDRDELVRWTRSDIDRYSPVTTENLDTGLTAAELAEAAVRESDNTALNLVLDRIGGP +EGLDDALELLGDATTEVVNYEPELNTITSGSIDDTTTADAFTESMTALQQTSYSTSSNRS +ILLDWMSGNKTGDPLVRAGAPAGWVVADKSGGAGP-IRNDIAVVTPPERSAVVITILTEK +NDPAAQFDNELVSETAAVVLH-- +>[subseq from] Class A beta-lactamase n=1 Tax=Spirosoma sp. KCTC 42546 TaxID=2520506 RepID=A0A514ZUZ3_9BACT +-qRLEQELERIAKLAKGKVGICALHLESGKQI-SLNVQDRFPMASTIKVAIAVQLFTLIE +QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT +EAVQNRVKALGIKGMSVDRTIIQLLAKIKTDPRDTSTPDAMVNLLAQIYRGTALKPESRA +LLLGVMERCRGGAARLKGYLPPNTVIAHKTGSLDGSATDDVGIITLPGDGHIAIAVFVGD +SPMPLAEREQTIAHTARSIYDYf +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium flavum TaxID=415851 RepID=A0A3D9CI51_9FLAO +-sALEQKINMITKGKNATVGVSVLGFENPFKY-SKSGDQKFPMQSVFKFHIAAAVLDFVD +QGKLSLDQKIPLNASNLLKWSPLRDKYPDGNVPLSEVIEYTVAKSDNNGCDILLRLLGGT +KTVQHFMDSKGVKGFRIRYNEEDMHKDWSVQYENYSTPNSAVTVLKKFYDGKLVSKKSTD +YLMKVMLSTSTGLNKIIEQLPKNTPVARKTGASGTGAENEIAIITLPDGKHYAIAVFVSN +SMETDTVNCKMISDISKEVWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Francisella noatunensis TaxID=657445 RepID=UPI000B597F20 +--EISNRLHNLEKLYGGKIGVYTINRNNNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM +TDNNLLNKEVKISANQIIGYSPVTKKHINQTMTVSELSKAAI-QSDNTATNLLIEELGGL +NNLNNFILSLHDHATKVAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILDKKHRL +LFKKWLLENDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMAIFYTQ +SQKDAKPNSKIIREVTKILLD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WXY1_9BACT +---LERAIKRLAESSGGIVGVSAIHIESGRRV-SVNGDLRFPMASVYKLPIALRLLQRID +RGELRLDGPITLSTHDFRPHSPIAEFANNKPLPLERLLELMLGESDNSASDKLLALAGGP +AAVTARMRALDITGLDISRPEGRLALAFADDPRDTSTPDAMAQLLVRVERREVLEPASME +RLLQITTATQTGPLRLKGLLPAGTPVAHKTGTMG-ATTNDVGIITLPDGGHVALAVFVKG +STLDVPSRERVIAEIARTIYDYy +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium soli TaxID=445961 RepID=A0A086A765_9FLAO +-sQLEQKISSFTKDKKATVGVSVLGFENGFKY-NKNGDRKLPMQSVFKFHIASAVLDLVD +HGKLKLDQKIFIKKSDLLEWSPLRDKYPAGNVPLSEIIDNTVALSDNNGCDILLQLIGGT +QTVQKFMDSKEVKGFQIKYNEAEMHQDWNAQYENYSTTNSAVQVLKKLYDGKLLSKQSTE +FLMNIILGTKTGVNKMIEQLPKNTPVARKTGSSGTGAENEIGIITLPNGKHYALAVFVSN +STESNEANCKMISDISKAVWDYf +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR459 TaxID=1500292 RepID=UPI00064908AD +---LEQKIHSILKNKKATVGVSVLDFENGFKY-DKNADKKLPMQSVFKFHIAATVLNAVD +QGKFSLDQKIVLNKSNLLEWSPLRDKYPGGNVPLSEVIEYTVAKSDNNGCDILLTLLGGT +QPVQKFMDSKGVKGFQIKYNEEAMHKDWKVQYENYSTTKSAVDVLKKFYDGKLLSKKSTD +YLMQVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFVSN +STETDAVNCRMISDISKEVWEYf +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. MYb7 TaxID=1827290 RepID=A0A2S8ZUJ9_9FLAO +-kELRNKINQIISTKNATVGISLKGIEDKDTL-SINGNKETPMLSVFKFHIALAVLNQVD +KGKLKLNQKFFIKKEDLLPWSPIREEYPQGNLTLDQLIRYTVSHSDNNGCDILLNIIGGT +ETVQKFINLQGIKDFTIKVNEKEMAS-FEKCYLNTTTPLATTELLEKFYKGKVLKKESTK +YLYQVMVETSRGLTWMKAGLPTGTELAHRTGISGRAAMNDVGTIKLPNGKHIVLSIYLKN +INEEMTDTEKIIADVTRAVWDYy +>[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. zg-579 TaxID=2663857 RepID=UPI0012B615BA +----DRRLAALEERYDARVGVSLLDTGDGAAY-SYRGDQRFGFASSVKVLVAAELLRRTG +--SAERAELVRWTQDDVDAYSPVTEAHVDRGLPLLRLAEAAVRESDNTATNLVLERLDGP +AGLTRGLLGRGDTTTVLADDEPGLNEVSPGSPANTTTPDAFVADLRALLGPEWLTDADRR +LLLGWMSGNPGGDPLIRAGAPAGWRVAQKSGGAGP-VRNDVAVLTPPDGAPVLLAVLTTR +LDPSAPYDDALVADAAEVAL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. 5_R23647 TaxID=2258964 RepID=A0A3D9AIC9_9FLAO +---LAQKVDSIIKDKKATVGVSVLGFEDGFKY-NKNAETKLPMLSVFKFHIAAAVLDLVD +KGKLSLDQKILIKKSDLLEWSPIREKYPNGNLPLSEIINYTVAWSDNNGCDILLRLIGGA +QVVQKFMDSKGVKDFQIKHNEEQMHKGAKYLYENYTTTNSLSQLYKNFYNGKILSEKSTK +FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN +STETDEVNCKMISDISKAVWDYf +>[subseq from] Beta-lactamase n=1 Tax=Pedobacter steynii TaxID=430522 RepID=A0A1H0CQ05_9SPHI +--ALQIKMDSIINSKKADVGVSVLYLSDQRIV-SVNGDKHYPMQSVYKFHLALAVLNQVD +QGKFKLDQKVLIKKSDLLPWSPLREKYPNGNVPLSEILKYTVSESDNNGCDILFRLIGGT +SKAHQFIKKQGIKEISIVGTEEEMHKDDQVQFRNWTTPKAANDLLKKFQEGKVLKKTTGD +FLMKIMEETVTGPGKIKGLLPQGTLVAHKTGNSGTAASNDIGIVTLPNGKKMLISTFVSM +SKENDKENDKIIAELAKAAFE-- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059XFH3_9BACT +-kTIEQRLNEIATQVPAKLGVAVFDFQTGKQI-GLHADERFPMQSVFKAPLAAAVFSLAE +QGKLSLDQKVTLEEKDLSAPESINEQWPGNRYTILELIEKAVAISDNTAADLLLSRVSGP +EGVDQYLEKHGIHGMHLDRSERELQPNYLSDPRDTTTPQAALTFLKKLESGELLSKDHTQ +QLLKMMSSNRYGTHRLKAGIPADAIFAHKTGTARVDAVNDIGIITLANGKKYAIASFLSG +TTLNDVEREAIHSEVARSVF--- +>[subseq from] class A beta-lactamase n=1 Tax=Kozakia baliensis TaxID=153496 RepID=UPI0013144F60 +----KQLISGIERKLGGRVGVSAVDTQTGLIL-QWRGSERFVMHSVFKWLLSAYLLHCSD +TGSRPLQTRVVIRASSIVGHSDQTKPFVGAAITLETLCLWMMSTSDNGAANTLLDVIGGP +YVLTAWLRSLGDTTTRQDTYEPGPTEG-SIDPRNTTTPDAMLALTQKIWLGSVLSPRSRE +TLLAWLRGSAVGGRRLRAGVPSSWVEGDRTGTGDPGVANDVAIFWPDGRKPILVSSFLEG +SANDLARLEDAQASIGRILANLf +>[subseq from] VEB-PER_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X6D3_9BACT +--DFKSQLESITKQIDGIAGVAVKDLEGKETL-ILNADHKFPMLSSFKFPIAMAVLDQVD +KGKLALDQKYHLTKEDIQLYSPLRDKFPDGNLTIADLLASMVSLSDNIACDILFKLAGGT +KPVQDYVHSLGVKDIAIVANEEQMGQDWNVQYTNWCKPGAMLQLLDIFYKGKNLSKSSHD +FLSKIMIDGPTGMNRIKGQLPKEAVVAHKTGTSGTNVVNDVGIVKMANGKSFAIVLFMSN +STAELKAIESVMAQVSKAAYEHy +>[subseq from] Putative beta-lactamase n=1 Tax=Scytonema sp. NIES-4073 TaxID=2005464 RepID=A0A1Z4PUC0_9CYAN +----QERLKNLDSAAQGKVGIGVLDLNSGQSW-FLNGKQRFPMQSVYKLPSAIAVLKQVD +EGKISLKQLVTIMRQDFAPSSPMIKEFKGDRIPLRNVLESSVGISDNTAADALVRLLGGP +QQVNAILGKLQIRNIRVDRLEQQMQPKYLTDPRDTATPEAMVDLLAKLNSNQLLSENSTA +LLLKIMTDSPTGQKRLKAGLPENWSIAHKTGTGAGTATNDVGIASSPDGKRVAIAVFIAG +SKAPLEEREKVMSNIASRVVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Erythrobacteraceae bacterium CCH12-C2 TaxID=1768805 RepID=UPI0008311D6A +---LAAELRIIEAAGNGTLGVEIYDTGSGLSV-GINQDRRFGHASSFKLSLAALLLQRHA +AGLIDADRRVTWTEADMIPHAPFTRERIATGATLRELARATQTTSDNPAANILLRQLGGP +AGLTQFWRSIGDEVSRIDRYEPEMNLVPASEFRDTTTPAAMARTVAKIVYGDVLPEAERA +ELKGWMIATETGLRRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKAAPITFACYFRA +RQTEQPIGEQTLARVGKVI---- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Runella limosa TaxID=370978 RepID=UPI00041CE8F3 +-sALRQQLQRVAATTNGVLGVGVIDLSNGDTV-SVNGQGHFPMQSVYKFHLALAVMNEID +KGKWTLEQKIKVTKKDLLPWSPLREKYPNGELPLREILEYTVAQSDNNGCDILFRLMGGT +KVVDKYIKSIGISDVNIVGTEEEMHADDRVQFANWSTPRSAAKLLAVFFEKKILSKHSWD +FVWNTMVSTTTGPRKIKGVLPANATVAHKTGYSGVNATNDIGIMQLPNGKYVAIAVFLSN +TPLPEAQCDRVIAEAAKVTWDYf +>[subseq from] Class A beta-lactamase n=1 Tax=Flavobacterium sp. Root420 TaxID=1736533 RepID=A0A0Q7FM44_9FLAO +-nDLRQQLNQIIASKNATVGISIKSIEDKDTL-SINGNLKAPMMSVFKFHIALTVLNQVD +EGKLSLDQKIFIKKKDLHEWSPMREDYPEGNLTLDKLLRYTVSHSDNNGCDLLINLVGGT +KVIQKFINKQGIKDFVIKVNEQQMET-WKNLYVNTTTPLTTTELLEKFYKGEVLKEETTK +YLYEIMVETSRGLTWMKAGLPEGTELAHRTGISGTNAMNDIGIVKLPNGKHFILSVYLKE +ITETKEDTEKIIADIAKATWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Francisella noatunensis TaxID=657445 RepID=UPI0013304E02 +--EISNRLHNLEKQYGGKIGVYTINRNDNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM +TDNNLLNEEVKISANQIIGYSPVTKKHLNQTMTVSELSKAAI-QSDNTATNLLIEKLGGL +NNLNTFILSLHDHATKVAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILDKKHRL +LFKKWLLENDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMGIFYTQ +SQKDAKPNSKIIREVTKILLD-- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=F8T7L4_ACIBA +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDQVPVQQLLQYSVSHSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQVAQAAYQ-- +>[subseq from] Class A beta-lactamase n=1 Tax=Ponticaulis sp. TaxID=2020902 RepID=A0A2D9RBG3_9RHOB +------ALQALEASAGGRLGVSATNLQTGRSI-SWRGDERFAMCSTFKWLLGAFYAQRMR +AQKERWDRFIPYTQADIVSYSPVSEPLVNGGMTLEGLCEATIMTSDNTAANVLLKDIGGP +EALTTFIRETGDLVTRLDRFEPELNIFVPGDERDTTTPNAMSGLMAHLLFGETGAFNATR +RVHDWMIKANTGLKRLRAGISDDYLVGDKTGTNSDSHSNDVGFVYTHKGGPVVISSYYNT +DDPFNPASDEVHAEVGRIAMK-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium sp. MOF25P TaxID=1664318 RepID=A0A1A7KDN8_9FLAO +---LAQKVDSIIKDKKATVGVSVLGFEDGFKY-NKNADTKLPMLSVFKFHIAATVLDLVD +KGRLSLDQKILIKKSDLLEWSPIREKYPNENIPLSEIINYTVAWSDNNGCDILLRLIGGT +QVVQKFMDSKGVKDFQIKHNEEQMHKGAKYLYENYTTTNSLSQLYKKFYEGKILSEKSTK +FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN +STETDEVNCKMISNISKAVWDYf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1Z3GWX7_ECOLX +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWDYy +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A140AQ53_ECOLX +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWDYy +>[subseq from] Beta-lactamase n=3 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A1B1SDU0_VIBPH +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWDYy +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A0B5WYI7_PROMI +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWDYy +>[subseq from] Beta-lactamase n=1 Tax=Spirosoma radiotolerans TaxID=1379870 RepID=A0A0E3V8P1_9BACT +-qRLQQELERIAGLAKGKVGICALHLESGKQV-SLNLQERFPMASTIKVAIAVQLFTMIE +KGQLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT +QAVQNRVKALGIQGMSVDRTIIQLLAKLKTDPRDTSTPEAMVNLLTQIYRGTALKPESRA +LLLGVMERCRGGAARLKGYLPPSTVIAHKTGSLDGSATDDVGIITLPDNGHIAIAVFVGD +SPMPLAEREQTIAHAARSIYDYf +>[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia TaxID=28110 RepID=A0A0E2ZJ48_9GAMM +--EISNRLHNLEKLYGGKIGVYTINRNNNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM +TDNNLLNKEVKISANQIIGYSPVTKKHINQTMTVSELSKAAI-QSDNTATNLLIEKLGGL +NNLNNFILSLHDHATKVAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILDKKHRL +LFKKWLIENDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMAIFYTQ +SQKDAKPNSKIIREVTKILLD-- +>[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia TaxID=28110 RepID=A0A0E1N5Y6_9GAMM +--EISNRLHNLEKLYGGKIGVYTINRNNNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM +TDNNLLNKEVKISANQIIGYSPVTKKHINQTMTVSELSKAAI-QSDNTATNLLIEKLGGL +NNLNNFILSLHDHATKVAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILDKKHRL +LFKKWLLENDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMAIFYTQ +SQKDAKPNSKIIREVTKILLD-- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=C1KGB9_ACIBA +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGTAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Beta-lactamase n=1 Tax=Francisella noatunensis subsp. orientalis TaxID=299583 RepID=A0A5C1S7D4_9GAMM +--EISNRLHNLEKQCGGKIGVYTINRNYNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM +TDNNLLNEEVKISANQIIGYSPVTKKHLNQTMTVSELSKAAI-QSDNTATNLLIEKLGGL +NNLNTFILSLHDHATKIAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILNKKHRL +LFKKWLLESDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMAIFYTQ +SQKDAKPNNKIIREVTKILLD-- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A333W4D3_ACIBA +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGTAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium hominis TaxID=420404 RepID=A0A3N0X7K2_9FLAO +-eELRKELNQIISTKNATVGISIKGSQEKDTL-SINGNMNMPMMSVFKFHIALAVLNEVD +KGKLLLTQKFLIKKEDLHEWSPILEEFPNGNLTLDQLLRYTVSHSDNNGCDILLKLIGGP +ETVQKFINKNGIKDFTIKVNENQMRT-WENLYINTTTPIATTELLEKFYKGKVLKKSTTK +YLYQIMVECSRGTTWMKAGLPAGTELAHRTGISGTNAMNDIGIIKLPNGKYVILSVYLKN +ITESREDTEKIIADIAKATWNYf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacteriaceae bacterium TaxID=2021370 RepID=A0A4Q3EML0_9SPHI +-nSLKNQVIEIAKEAKATIGISIFNIETRKRV-SYNENLHLPMQSVMKFPIAITVLHKID +EGKLKQDQLIHIDKEDLPEYSPLRDKFPEGNVSIKDLLSYMVSLSDNDACDILLKTIGGP +KQVDTYMHQLSVKNISVKASEFQMAQNWNVQFTNWCEPAAMTQLLDLSLRANFLSRNSHA +FLWKILQETSTGPKQLKGLLPEGTIVAHKTGRSGTAATNDVGVITLPNGKHLAIAIFISN +SSVDLATRESVIARIAKAVYK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Tropicimonas sp. IMCC6043 TaxID=2510645 RepID=A0A4V1V621_9RHOB +---VAAAIERVATGLAGRIGFAAQEIGGDQVI-AFNGDETFAMASTYKVAIATAIMDRVD +RGELGLDQMVEITPDMMMIDAALSDTFVHPGLSVANLMEIMITESDNTATDTLIGLAGGA +AAVTENLRRLGITDFRVDRTTGEIIGDFEADPRDHATPLAMLQLLLAIDSGTAMSAESRD +FLIDVMSRTRTGAARLMGLLPRGTPVAHKTGTIG-GVANDVGYITLPDGRRFAIAVFTSS +SETSEADRDRAIAEVARSLFDYf +>[subseq from] Beta-lactamase n=2 Tax=Rhodococcus sp. MEB064 TaxID=1587522 RepID=A0A0D0KLP2_9NOCA +-eDFSTELQAVEDRYDVTVGVSLLDTGTGETI-SYRGAERFGFASTVKVFLAAEFLRRTP +--QDARDDIVRWSAADIERYSPVTTARLDTGLTAAELAEAAVRASDNTATNLVFDRIGGP +AELDAALSRLGDEVTDIVDVEPGLNTVEPDSTANTTTADAFTANMAALRGDGSSTDADAA +TLVEWMSGNATGDALVRAGAPSGWTVADKSGGAG-GVRNDIAVVTPPGHPPLVLTVLTRK +NDPSAPYEDAAVSESAAIVLN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X1K5_9BACT +-sKLAAQVEKIAGEARGRVGAAVMLIETGEAIvSLNADQRFPMQSVYKLPIALVVLRRVD +RGALALEQRVRVEQSDFISHSPIRDKNPRGVMSLRDLLRFAISESDGTASDVLMRLAGGA +DVITRELRELGVSGVMVVNTEKELGENQSLQHQNWATPESMLVLLRALQEGRGLSVQSRI +LLLQLMAESTPGPRRLKGRLPPGTVVAHKTGTSGTAATNDVGLITLPDGRHLAIAVFVSD +SPADESVREGVIARIARAAWD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Scytonema tolypothrichoides VB-61278 TaxID=1233231 RepID=A0A0C2LAX3_9CYAN +---LQERLKNLISAAQGRVGIGVLDLNNGQSW-FLNGKQRFPMQSVYKLPSAIAVLKQVD +EGKISLKQLVTIMRRDFAPWSPIIKEVRGDRFILRNVLERSVGMSDNTAADALVRVLGGP +KQVNAILKQLSIRNVRVDRLEQQLQPKYLRDERDTATPEGMVDLLARLNSNKLLSQNSTT +LLLKIMTDSPTGEKRLKAGLPNNWSIAHKTGTGPGTATNDVGIASSPDGKRVAIAVFIAG +SKAPLEVREKVMSEIASAVIQ-- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium ginsenosidimutans TaxID=1176536 RepID=A0A5B8S350_9SPHN +--TLEATVASLADAAQGRIGVAAMDLGTGRTV-AVLGDQPFPMASTSKIAIAATFLDLVD +QGKRSLSDRFPLMIPQRSASSAVAPVRPGTMISAQGLIELSITRSDNPATDALLAAVGGP +AAVNRWMRKAGLSGMRLDRDIATLVRATTVDLRDSATPLAMVQLLAGLHQGRWLSASSRS +VLLGAMERCVTGKRRLRAMLPEDARIAHKTGTLNN-TSSDVGIIQTPDGRSIAIAVYVTG +QG-GKPNRDYRIASISRAIYDGy +>[subseq from] Beta-lactamase class A n=1 Tax=Actinoplanes xinjiangensis TaxID=512350 RepID=A0A316FFZ9_9ACTN +----HSRLAELERRFGARLGVYAVATGTGATV-AHRADERFPYCSAFKGLAAAAVLHGTP +--LSGLTERVRFTRADVEPNSRKTRERITTGMTLGELCDAAIRFSDGTAGNLLLRRLGGP +AELTAYLRTLDDTVTLAARTEPALWRDTPGDRRDTTSPRAIGTDYQKIMVGDALPGNARA +YLRDLLERADESRERIRSVIPRGWTVANKTGTGDYGPANDIALVWQSASDPLVLSIMSRR +TGREGEADNTLVAEAARYVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000A6D6424 +--TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNESNLS +LLKQIMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] CIA family class A extended-spectrum beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=UPI000B515EB2 +---LDEKISAVIKDKKATVGVSVLGFENAFKY-SKNGDEKLPLLSVFKFHLACAVLDMAD +KGKFSTDQKFLIKKSDLLEWSPLREKFPEGNLSLGEIITYTVAQSDNNTCDFLLRLIGGP +QVVQHFMDSKGAKDLQIKYNEDDMHRDWKNQYGNESSTNATVSLLKKFYDGKLLNKKSTD +FLMQIMLGTTTGTNKIVEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVSN +STETEKVNTRMVSDISKIVWDNf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Spirosoma terrae TaxID=1968276 RepID=UPI0013D62C0D +-kELQTKIEQVIKNKKATVSVGIYNFGNHQTL-LINGDKHVPMQSVYKFHVALAVLKEVD +KRRFKLTQKMHVKKSDLTPHSPMGEDYPNGELPLSDIIRYMVADSDGSACDYLFRLLGGP +KQVEAFIHQLGIRDVSIRDTEAMMQANWNVQYTNWTTQTAMLSLMKLFYQHKILSASSHK +FLWNVMLGTTTGQDRLKKLLPAGTLVAHKTGTSGMGAVNDAGFIALPNGGHMAISVFVTN +STERMATNEKIIADIAKLAYDHy +>[subseq from] Extended-spectrum class A beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=G9MB51_9FLAO +---LDEKISAVIKDKKATVGVSVLGFENAFKY-SKNGDEKLPLLSVFKFHLACAVLDMAD +KGKFSTDQKFLIKKSDLLEWSPLREKFPEGNLSLGEIITYTVAQSDNNTCDFLLRLIGGP +QVVQHFMDSKGAKDLQIKYNEDDMHRDWKNQYGNESSTNATVSLLKKFYDGKLLTKKSTD +FLMQIMLGTTTGTNKIVEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVSN +STETEKVNTRMVSDISKIVWDNf +>[subseq from] CIA family class A extended-spectrum beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=UPI00076E375B +---LDEKISAVIKDKKATVGVSVLGFENAFKY-SKNGDEKLPLLSVFKFHLACAVLDMAD +KGKFSTDQKFLIKKSDLLEWSPLREKFPEGNLSLGEIITYTVAQSDNNTCDFLLRLIGGP +QVVQHFMDSKGAKDLQIKYNEDDMHRDWKNQYGNESSTNATVSLLKKFYDGKLLTKKSTD +FLMQIMLGTTTGTNKIVEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVSN +STETEKVNTRMVSDISKIVWDNf +>[subseq from] class A beta-lactamase n=1 Tax=Mastigocladopsis repens TaxID=221287 RepID=UPI000526D6C8 +---LQERLKNLDSAARGKVGIGVLDLNSGKSW-FLNGKQRFPMQSVFKLPAAIAVLRLVD +DGKVSLDQSVTITRQEFAPSSSMIKEFKGTSFTVRKLLERSVGMSDNTAADALVRLVGGP +QQVNAILGKLKIRDVRVDRLEQQLQPKYLTDPRDTATPEGIVDLLAKLHSNQLLSRNSTA +LLLKIMTDSPTGQKRLKAGLPKNWWIAHKTGTGPGTATNDVGIASSPDGKRVGIAVFIAG +SKAPLEEREKLMSEIASTVVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X1S5_9BACT +-sALQNQIKEIAAEAKGKVGVTAVVLESGETVaSLNPQEHFPMQSVYKLPISMAVMKAVD +AGKVKLTDKVTISKSEFVGHSPIRDQHPNGALTVEELLRYALSESDGTASDVLMKLAGGP +AAVQA-LTELSIKDLIVLDTEQTFTQDKTAQYRNWATPEAAVALLRALHESRGVSESSQS +LLLKFMTESTPGAKRLKGMLPAGTPVAHKTGTSGTAATNDIGIITLKNGKHVAIAVFVSD +SPADQVTREGVIAKIAKAVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V2RJ99_9BACT +-pQLENELAEIARQARGRVGVAAKLLGSKQTV-LLNSAEHFPMQSVYKLPISMAVVQQVD +QGKLKLDQMVRVAKDDFIGRSPIRDKFPNGVLSVSDLLRYAISESDGTASDVLMKVAGGP +EIIQSFLTTIGIADMKIIDTEKALARDRSLQYRNWTTPDAAVALLESLDEKRELSQTSRS +LLMKLMAESTPGKNRLKGLLPAGTYVAHKTGTSGTAATNDIGIITLPNGQHLAIAVFVSE +SPAVETTREGVIAQLAKRVFETw +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. Leaf201 TaxID=1735672 RepID=A0A0Q4C684_9FLAO +---LKKQINTIIKGKNATVGISVLNLEDGFSY-DKNAGKKLPMQSVFKFHIAAAVLDLAD +KGKLSLDQKVTLDASNLMEWSPLRDKYSGKNVPLSEILEFTVAKSDNNGCDILLQLLGGT +ETVQKFMDSKGIKGFQIKYNETEMHKDWTAQYENYTTAKSAVDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGKNKLIEQLPENTPAARKTGASGTGAENEIAIITLPDGRHYAIAVLVSN +STETNAVNCKMISDISKTVWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas yeongjuensis TaxID=377616 RepID=UPI001391E434 +---LQQELDRLVSSFDGEAGVYALDLRSGRTA-HANAEVGFPMASTVKVPVAVHILGLVD +EGKLDLRQQVLLKEGDIYPGGPVDIHLTPGSITLRDLLHMMLTVSDNNATDILIRLGGGA +AAVNARMRALGVQGIRVDRYIWEMLSLYNDDPRDTSTPAGMASLLRLVWEGKALKPATTD +ALKTILLDCRTGQDRLKGMLPEATPVAHKTGTVDE-VINDVGVITLPAGGDVVVAVFLKS +DQGD-RARDRMIAQVARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter freundii complex sp. CFNIH2 TaxID=2066049 RepID=A0A2K9PJC7_9ENTR +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLG----- +------------------------------------------------------------ +----------------------- +>[subseq from] VEB-PER_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X5T9_9BACT +--DFKSQLESITKQIDGIAGVAVKDLEGKETL-ILNADHKFPMLSSFKFPIAVAVLDQVD +KGKLALDQKYHLTKEDIQLYSPLRDKFPDGNLTIADLLASMVSLSDNIACDILFKLAGGT +KPVQDYVHSLGVKDIAIVANEEQMGQDWNVQYTNWCKPGAMLQLLDIFYKGKNLSKSSHD +FLSKIMIDGPTGMNRIKGQLPKEAVVAHKTGTSGTNAVNDVGIVKMANGKSFAIVLFMSN +STAELKAIESVMAQVSKAAYEHy +>[subseq from] Beta-lactamase n=1 Tax=Halioglobus sediminis TaxID=2283635 RepID=A0A3L7DVG7_9GAMM +---VAAAIERVVTKLAGRIGFAAQEIGGDEVI-ALNGNETFAMASTYKVAIAAAVLDRVD +RGELRLDQMVDVTLDMMMIGDAALNTHPGLQLSIANLIEVMITESDNTATDISMGLAGGP +AAVTKYLRRLGITDFRVDRLTGEIIGDFEADPRDQATPLAMLLLLLAIDSGTATSPESRD +FLIDVMSRTRTGAGRLKGLLPRGTPVAHKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS +SETSETDRDRAIAEVARSLFDYf +>[subseq from] VEB family class A extended-spectrum beta-lactamase n=1 Tax=Aeromonas hydrophila TaxID=644 RepID=UPI00090A8AF3 +--NLTLKIENVLKEKNARIGVAIFNSNEKDTF-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus nepalensis TaxID=214473 RepID=A0A3A0SD35_9STAP +---SAKTFEQIEQDNDTIVGVYGVNTANGKHI-QHRSDERFAFASTYKAIASGILLQNTA +--TSTLNKKIDIKKDDIVANSPVTEKYVGSQMTLKALIQASMLQSDNTANNKIINEIGGI +KGFHEELKQLEDNISNPQRLEPELNLYDPTSTADTTTPKAAAMTLKHILTNEDMSKANRN +LLKNVMIHNETGDTLIKAGVPKQAVVGDKSGQGTYGTRNDLAFIYPKNQEPIVLAIYTKK +DGKDAKPNDKVIQMATKTAME-- +>[subseq from] Beta-lactamase n=1 Tax=Asaia bogorensis NBRC 16594 TaxID=1231624 RepID=A0A0P0YGZ0_9PROT +hqALSDIATRYEKLSGGRLGVHIFCPESGTAL-SWRGEERFRMCSSFKASLAACVLACCD +RDEDDLTRRIAFRESDFKEWAPVAARNRDAGLSLAALCAGAVTMSDNICANMLLRHIGGP +AALTRFWRDSGDEITRLDAYEPELNRPSANPDDNTTSPVAMARTLHRLIHGTLLHPNSAA +LLRSWMINCTTGTQRLRAGLPAHWVVGDKTGNNGKDIAADIAFASADAGKSVIIATYTAG +GTPDETQFRRVFHDIGALA---- +>[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia subsp. philomiragia (strain ATCC 25017) TaxID=484022 RepID=B0TZF6_FRAP2 +---ISNHLHNLEKLYGGKIGVYTINRNNNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM +TDNNLLNKEVKISANQIIGYSPVTKKHINQTMTVRELSKAAI-QSDNTATNLLIEKLGGL +NNLNNFILSLHDHATKVAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILDKKHRL +LFKKWLLENDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMAIFYTQ +SQKDAKPNSKIIREATKILLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter arachoides TaxID=1850444 RepID=UPI00103CBDA4 +--RIEQRIAQIAEGSRGRIGVAAIDLATGQEI-SVLGDQRFPMASTSKIAIAATFLEMVD +QGRASLSSEYPMLYAVSSRSTSVAPVRRGEYMSAANLIEIMITRSSNQATDALLQAVGGP +GAVNAWAQRAGLTDFSLDRDIATLVRAHHIDLRDSATPQAMVQLLSGIYQGRWLSAESRR +VILGAMERCRTGTRRIPAMLPSGVSVAHKTGSLNN-TSSDIGILTAPDGRTIAVAIYVTG +QG-SRPNREARIASIARAIYDGy +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0H4IVL0_PSEAI +--NLTLKIENVLKEKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. KLBC 52 TaxID=1862702 RepID=UPI000E0A87C0 +---LEQKINSILKNKKATVGVSVLGFENGFTY-NKNADKKLPMQSVFKFHIAAAVLNDVD +QGKLSLDQKIKLDQSNLLEWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLRLLGGT +QTVQKFMDSKGVKGFQIKYNEEDMHKDWNVQYENYSTTKSAVDVLKKFYDGKLLSKKSTD +YLMKVLWSTSTGLNKMVEQLPKNTLVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN +STETDAVNCRMISDISREVWEYf +>[subseq from] Beta-lactamase n=1 Tax=Sporocytophaga myxococcoides TaxID=153721 RepID=A0A098LJH2_9BACT +--SLRRDIEKVLSTKKAKVGVSIMGDNGRDTL-SINGDKHFPMQSVFKFHIALTVLSQIE +QGKFSLDQIIKIDENQMLPYSPIREKYPHGVLKISEILEYTVSLSDNVGCDVLLKLIGGP +QVVENFITEKGFKDFSVKINEEVMQNNWDLQFKNWTTPKTSTQILAYFYDKKILSAEHHD +FIWTIMKQTETGKNRLKGQLPEGTVVAHKTGWSGTAAVNDIGIIFLPNGRHYFISVFITD +SKEDTAVSEKIIADISKVVFDYf +>[subseq from] Beta-lactamase n=1 Tax=[Flexibacter] sp. ATCC 35208 TaxID=1936242 RepID=A0A1V2BD02_9BACT +--ALRKTIDSIATHSNAHIGVAALLLETGDTL-TYRGNDHYPMQSVYKFPISLAILHQVD +IGKYKLDEKILITKDDIMPHSPIRDAHPNGGMTLREISRYNIMESDGTACDVLLRLLGGT +KKTNAYIKSLGVKGINIATTEKEQQSNDTTQYRNWATPIGITQLYKIYLQNKVLSSASYN +TLWKDLAGSYPGANRIKGLLPKGTIVAHKTGTSGTAATNDSGIIILPNGKHLILTVFVSD +SKGSDAEREAWIAQISKAIFDHw +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. CBo1 TaxID=1869230 RepID=A0A1B9Y8A5_9FLAO +---LDQKISSIIKDKKATVGVSVLGFEDGFKY-DKNANKKLPTLSVFKFHIACAVLDLVD +QGKLSLNQKVVLKESELLPWSPIKEKYPTGDLTLDEIIDYTVALSDNNGCDKLLKMIGGT +QTVQKFMDSKGVKGFQIKVNEDEMHKDWKNQYKNYSTTKSAVTLLKSFYDGKILSKKSTD +YLMKIMLGTKTGMNKLVEQLPKNTPIVHKTGASGTVAENDMGIVTLPNGKHYAIAVFVNN +STETEVVNCKMISDISKIVWDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium aquidurense TaxID=362413 RepID=A0A1H3S746_9FLAO +-sDLRQQLNQIIATKNATVGISIKSIEDKDTL-SINGNLKAPMMSVFKFHIALTVLNQVD +EGKLSLEQKIFIKKKELHEWSPMREDYPEGNLTLDKLLRYTVSHSDNNGCDILIDLVGGT +KVIQKFINKQGIKDFVIKVNEKQMES-WKNLYVNTTTPLATTELLEKFYKGEVLKESTTQ +YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISGTNAMNDIGIVKLPNGKHFILSVYLKD +ITEKQEDTEKIIADIARATWDYf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8QR85_9BACT +---LQQRTTQIAALAKGRVGVSAVLLETRELIaSLNSQDHFPMQSVYKLPISMALMKQVD +AGKIKLEQRVKIAKEDYVGHSPIRDQYPNGTLSVTELLRFALSESDGTASDVLMKLAGGH +EAVQAYLTDLGIKDMMILDTEQSFTQDHSLQYRNFATPDAAVDLLRALYEHRGLSESSQA +LLLKFMAESTTGPKRLKGLLPAGTTVSHKTGTSGTAATNDIGLITLPNGKHVAIAVFVAD +SPADEITREATIAKIAKAVWD-- +>[subseq from] Beta-lactamase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E2NDE0_9SPHN +-eQLAAQIDGLEAASGGRLGLALFSRDEGLVF-AHRGAVRFAMCSTFKLALAAMTLETAD +----VREERLDFGADDILSYAPYAKERAQIGMSGLEAAHHAVTLSDNTAANLLLVRLGGP +EAFTAWLRDAGDRVTRLDRNEPTLNENAPGDPRDTTTPGAKAELVGNLLWGDRLSATDRG +ILHGWLVETSTGMARLRGGLPDGWNAGDKTGTCGQPEFNDIAVFETPSGSRYVLAAFLDR +PKGTSAEADAVLADAARVVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. PAMC 26621 TaxID=1112213 RepID=UPI00028896DC +----AAALAALERRHGGRLGVHALDMHTGRTL-GYRADESFKLMSSFKGLLAALVLSNVS +KHRDSLQSPVRYGPSDLLAASPVTQANVARGMTVRELCEAIMLRSDNAAANLLMRRSGGP +AGLTAFLRSIGDRVTRIDTYEGHLTDH--PLPADSSTPRAVTETVRRILCGPVLPIAGRR +VWEGWMAGNIVGRARLRASFPANWIAGDRTGTGD-GICNDFAFARRPGIAPLLLSAYYTA +PGSELPDQEAVLRAVSRLVV--- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Runella sp. CRIBMP TaxID=2683261 RepID=UPI001411FFDD +-dALRSNIQQIVSSKNAIVGVSIIGNNGKDTM-SLHGDRRFPMQSVFKFHIALAVLSEID +KGKLSLDQKIEIRKDELLPWSPLRDENPNGGFTIEKLIQYSVSNSDNTACDVLIRLIGTP +KTVEEYFKKNNIQDIQITYNEEEMQSKWENMFQNWTTPKAASETLKMFYENNLLSKSSYD +FFWKTNIETTTGENRIKGQLPKGTIVAHKTGWSGTAAVNNIGIVFLPNGEYFIISVFVSE +SKENFDTNEKIIADIAKATYDFy +>[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia TaxID=28110 RepID=A0A0B6D7N7_9GAMM +--EISNRLHNLEKQYGGKIGVYTINRNNNSNF-SHNQSFYFPICSTYKFLVIGAILKQSM +TDNNLLNEEVKISANQIIGYSPVTKKHINQTMTVSELSKAAI-ESDNTATNLLIEKLGGL +NNLNKFILSLHDHATKVAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILDKKHRL +LFKKWLLESDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMAIFYTQ +SQKNAKPNSKIIREVTKILLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Haloactinobacterium sp. F-300 TaxID=2666133 RepID=UPI0012D5039F +------ALVRLEEESGVRIGAVGI--SSAARV-AHRAEEAFPMCSLFKVLAVASLLRERA +YDDAYWAEPIPFGPADLVEDSPVTSATTTWAMSPTALADAALRFSDNTAGNLLLAELGGP +EAITTFAADLGAASTRLDRWEPELNEATPGDLRDTSTPSDIALLYRALLLEDRAGVLTGA +RLRDWMLRNTTSAARIRAGLDGDVELADKTGAGSYGVVNDAGMLWSAGSDPVTLVILTRT +DDPAAANDNEVVAEATRIIMS-- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X3I7_9BACT +--RLQERLNNLDSSAQGNVGIGVLDLDTGERW-FRNGKQRFPMQSVFKLPVGIVVLKLVD +EGKLSLNQTVTITREQFAPWSPILKEIKGDRFTVQYLLQRAVGDSDNTAADALVRLVGGP +EQVTAILGRMSLRNIRVDRLEQQLQPRYLTDPRDTATPEGMIDLLVKLQSRQLLSEDSTA +LLLKIMTDSPTGQKRLKAGLPQGWSIAHKTGTGEDVATNDVGLISSPTGKHIAVAVFIAG +SKAPLEQRESVMSAVASAVIQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium aquifrigidense TaxID=558021 RepID=A0A543EL48_9FLAO +---LEQKINSILKNKKATVGVSVLGFENGFTY-DKNADKKLPMQSVFKFHIAAAVLDAVD +KRKLSLDQKIKLDSSNLLQWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLKLLGGP +QTVQKFMDSKGVKGFQIKYNEEEMHKDWNVQYQNYSTTKSAVDVLKKFYDGKLLSKKSTD +YLMKVLWSTSTGMNKMVEQLPKNTPVARKTGSSGTGAENEIGIITLPNGKHYALAVFVSN +STETDAVNCRMISDISREVWEYf +>[subseq from] class A beta-lactamase n=1 Tax=Oceanibium sediminis TaxID=2026339 RepID=UPI000DD322E4 +--AVGAAIERVATGLAGRIGFAAQEIGGDDVI-AFNGDETFVMASTYKVAIAAAVLDRVD +RGELSLDQMVDVTPDMMMIDAALSDTFVHPGLSVANLIEIMITESDNTATDISMGLAGGP +AAVTEYLRRLEITDFRVDRTTGEIIGDFEADPRDQSTPLAMLQLLLAIDSGAATSAESRD +FLINVMSRTRTGAGRLKGLLPRGTPVANKTGTIG-GVANDVGYITLPDGRRFAVAVFTKS +SATSEADRDRAIAEVTRSLFDYf +>[subseq from] Beta-lactamase n=2 Tax=Novosphingobium nitrogenifigens TaxID=378548 RepID=F1Z6G2_9SPHN +-----ARLSALETRAGGRLGAFVLDSRSGRGF-GWRGDERFALCSTFKLSLAALVLREIE +AGRLDGAETLYYSIIDVLPASPRTGDAAGKGLPVLALAQAALETSDNLAANLLLDRLGGP +EALTAFWRQVGDTDSRLDRHEISLNRVYAGDVRDTTTPMAMARTVSALTTGTVLTSASRA +QLWGWMKACGTGLARLRAGLPAQWQGGDKTGTFAPAHVNDIALVLAPDHAPIAVTAYYEP +AGAIAPASETVLAEVARIAAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Leucobacter musarum TaxID=1930747 RepID=UPI0006A77FB7 +-rTLSQRLNRLQGQYGARIGLFALDTLTDQVV-GFNEDHRFGYASSIKALLAAFFLERVT +--GESRGEQVTWTQEQVDDYAPVTGEHVGERMSVQELAEATVRTSDNLAFNLVLEKLGGP +DAFQQWLRDQGDQATEFASYEPFVNDIVDGDTANTSTPASMTSTLAQVVTSLGRESADQD +LLVEWMSGNATGDTLLRAGVPAGWTVADKSGGAA-GMRNDIAVITQHGQDPVIVSVLTTK +RDPKEKYDDQLLADVAEALF--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=F4Y5N6_KLEOX +------------------------------------------------------------ +-----GNKRLEIKKADLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP +EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIGVIWPENHAPLVLVTYFTQ +----------------------- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=Syntrophus sp. PtaB.Bin001 TaxID=1811710 RepID=A0A1V4Y0Q9_9DELT +--RLEREMKRLASQAGGTVGISALHIESGQHF-SFNGKERFPMASVYKIPIAVRLLNRVD +RGEVSLDRTVALSTCDFHPGSGLVQKFKNKKYTVRELLELMLLVSDNTASDALLKLAGGP +EAVTSFMKTLGINDIQVSRSTLNMLACFFSDIRDTATPEAMTCLIAKVHSGTALKPESAS +MLLEIMERCRTGKSRIRRMIPPGMAVADKTGTIGKGMVNDAAIMTLPAEGHVALTIFIKT +SEQTVSQQEQAMAQMARYLYDYf +>[subseq from] Beta-lactamase n=1 Tax=Muricauda sp. SM1704 TaxID=2292706 RepID=A0A371JRV6_9FLAO +--TLKLKIEDVINSKKAVVGVAINGMEPKDTL-SINGQGHFPMQSVFKFPIALTILSEID +KGNLSLDQKIEIKKSELLPWSPIREKHPEGGFTIAEIIEYTVALSDNVGCDALLRLLGEP +QAVENYFSSLGFKDFAVKINEETMQGNWDLQFLNWTTPKEANKILAAFYENKLLSKESYD +FIWNIMKGTKTGKNRLRGQLPEETIVAHKTGWSGTAAVNNIGIVFLPNGEYFAISVFVSE +SPEDFETNEKIIADISKAAWDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Dyadobacter psychrophilus TaxID=651661 RepID=A0A1T5FD77_9BACT +--DFKSQLESITKQVDGITGVAIEDLQRNETT-ILNPDHKFPMLSSFKFPIAMAVLDQID +KGKLSLTQKYHLTKEDVQLYSPLRDKYPDGNLTIADLLTSMVSLSDNIACDILFKLAGGT +KPVQDYVHSLGVKDIAIVANEEQMGQDWNVQYTNWCKPGAMLQLLEIFYKGKNLSKPSHE +FLSKIMIDGPTGLNRIKGQLPKDAVVAHKTGTSGTAAVNDVGIVKMPDGRSFAIVLFVSN +STADLKAIELVMAQVSKAAFDHy +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Chryseobacterium hagamense TaxID=395935 RepID=A0A511YJ47_9FLAO +---LDSKINSIIQGKKATVGVSVLGFENGFKY-SKNGEKKLPMQSVFKFHIAAAVLDRVD +KGKLSLDQKVSLNAANLMPWSPLRDKYPNGSVPLSEIIEYTVAKSDNNGCDILLKLLGGT +GTVQKFMDSKGVKGFQIKYNEADMHQDWNAQYKNYSTAVSATDVLKKFYDGKLLSEKSTA +YLMKVMLSTSTGMNKLIAQLPKDTPAARKTGASGTGAENEIAIITLPDGKHYAIAVFVSN +SAETQEVNCKMISDISKLVWDYf +>[subseq from] Beta-lactamase n=1 Tax=Nocardioides lianchengensis TaxID=1045774 RepID=A0A1G6V7G0_9ACTN +------------------------------------------------------------ +----------------------------EPGASLREDLRRAVSDSDNDAANRLIDRLGGP +ASVTRFARTLGDDVTRLDRREPDLNSAVPGDPRDTTSPRAIAATYRTLVLGDALPRGARD +LLTDLLVGSTTGAERIRAGLPEDWWVGDKTGTGGYGSTHDVAVVRPPGGEAFVLAVYTSY +DDPAAEPDQDLVAAVARLVVS-- +>[subseq from] Extended-spectrum class A beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=G9MB49_9FLAO +---LDEKISAVIKDKKATVGVSVLGFENAFKY-SKNGDEKLPLLSVFKFHLACAVLDMAD +KGKFSTDQKFLIKKSDLLEWSPLREKFPEGNLSLGEIITYTVAQSDNNTCDFLLRLIGGP +QVVQHFMDSKGAKDLQIKYNEDDMHRDWKNQYGNESSTNATVSLLKKFYDGKLLTKKSTD +FLMQIMLGTTTGTNKIVEQLPKGTPVAHKTGSSGKPAENDMGIITLPNGKHYAIAVFVSN +STETEKVNTRMVSDISKIVWDNf +>[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=D0UY02_ACIPI +--NLTLKIENVLKAKNARIGVAIFNSNEKDTF-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Beta-lactamase (Fragment) n=19 Tax=Bacteria TaxID=2 RepID=A0A345N8P8_PRORE +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQVAQTAYQ-- +>[subseq from] Beta-lactamase n=1 Tax=Pedobacter terrae TaxID=405671 RepID=A0A1G7PYT8_9SPHI +---LNAKIQQIVASKHAKVGIAIKGPGIKDTL-FINGDQHFPLQSVFKFHVALAILSQVD +QGKFSMSQKINITKKDLLPYSPIRDRYPNGVLPLSEILAYTVSQSDNIGCDILLRMIGGP +EFVEKYCNSIGIQDVSIKINEEEQQSNWNAQFKNWTTPKAANEILELFYMNNLLSKKSYQ +FIWKVMRETKTGEGRLRGQLPTKTIVAHKTGSSGTAAVNDIGVVFLPAGAHYFISVFVTE +STENAATNEKIIADINKAAWDYf +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. JC507 TaxID=1978493 RepID=UPI0010A88ECF +-sALDQKINSIIKDKKATVGVSVLSFESNFKY-SKNGDKKLPLLSVFKFHLASTVLDMAD +KGKFSTDQKFLIKKSDLLEWSPLREKYPEGNLSLGEIIKYTVAQSDNNTCDFLLRLIGGP +KVVQQFMDSKGVKDLQIKYTEDDMHKDWKNQYGNESSTNSTVVLLKKFYDGKLLSKKSTD +FLMQIMLATTTGTNKIVEQLPKRTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAIFVSN +STETERVNTRMVSDISKIVWDNf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobacteriales bacterium TaxID=2044944 RepID=A0A4Q3EUL5_9SPHI +-aPLRAALQQVADTTDGRLGIALWQVEAGDTI-TLGNSQHYPMQSTYKLPLALYILHLAD +EGKLKLDEPIYIPASTLDTWSPMLKDHPNQGLSIQELLAYTIGLSDNNACDILFRQAGGT +QPVHKYIHSLGIQDMAIAATEAEMAKGWQVQYTNWCTPMAMAQLLHRLYNGQLLGKASTA +LLMDMMANSLNSASRIKGMLPPGTPVAHKTGTSNTGAVNDVGIITLPNGKHLIVSVYVSN +FTGGTARGEAIIAVVSRLAYNYf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A516TQ62_PSEAI +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Beta-lactamase n=8 Tax=Bacteria TaxID=2 RepID=A0A0C4XPR7_9BACT +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=Q9AMJ6_PSEAI +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Class A extended-spectrum beta-lactamase VEB-23 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A650A9A9_ENTCL +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Beta-lactamase n=33 Tax=Bacteria TaxID=2 RepID=Q7BVU7_ECOLX +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X222_9BACT +-sDLTGQIKQIAKTVGGRVGVAATILETGETV-SLNAKDRYPMQSVYKLPIGMTVLSQID +AGQLNLSERLRIEKENVLKTSRILEKFPDGTQTIEELLRLMVSESDNTASDALLRLVGGP +EAVMKFLNKNEIFGIEIANYEKEFAADWRVQYKNRAAPKAAIELLRALHESRGLSAQSQA +LLLKYMTDSPTGPRRLKGLLPEDAQVAHKTGTSGTAATNDIGIVTLPDGRHLAIAVFVSD +SPADETIREETIARIARAVWDYw +>[subseq from] class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI00015D78FC +--QVTNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM +TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL +KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL +MFKQWLIASNTSNNHIAVEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ +SQKNAKPNSKIVREVTKILLN-- +>[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A1B1LRY6_VIBPH +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=A3RJX8_ECOLX +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A1YTM5_PROMI +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Beta-lactamase n=3 Tax=Enterobacterales TaxID=91347 RepID=B1P2H7_PROMI +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Beta-lactamase n=2 Tax=Pedobacter TaxID=84567 RepID=A0A4R8P4I3_9SPHI +---LNAKIQEIIASKHAKVGIAIKGPNERDAL-SINGNEHFPLQSVFKFHIALAVLSQVD +KGKFSLSQKIKISKKDLLPYSPIRDRYPNGVLPLSEILAYTVSQSDNVGCDILLRMIGGP +EFVEKYCKSVGIHDVSIKINEEEQQGNWNSQFKNWTTPKAANNILELFYMNNLLSKKSHH +FIWKVMRETKTGAHRLRGLLPKNTLIAHKTGSSGTAAVNDIGIVFLPNGSYYFISVFVTE +STENEATNEKIIADINKEAWEYf +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=A0A4Q3FIC0_9RHIZ +--KLDKGIEGIEQAAKGRLGVALMDLRDRKLW-SHRGSETFPMQSVFKLPLAVAVLQQVE +AGTFKLDQPITVTRKDFSLHSPLAKAFKGERYPLRELIRLAAGESDNTAADLLMREIGGP +QVVTKMLRDGGIQGMSVDRYERQFQPNALKDKRDASTPEASAQFLEAFAKGNWLRPAHAA +LLTRIITETKVGADRIKAGLPEGSRLAHRTGAGLNHATNDIGIATLPDGRRFVIVTYLAG +SRADAKEREAALAEVARLAVS-- +>[subseq from] Beta-lactamase n=1 Tax=Porphyromonadaceae bacterium TaxID=2049046 RepID=A0A3B8VWB4_9PORP +-qNLQQKIDSIVVGKQAEIGVAIRNLDTGETL-GLHLDERFPMQSVFKFHLALQVLNEVD +KGNLDLNDMIVLQPTDLLEWSPMRDAYKAGEINIVTLLDLSVKRSDNNACDILLRQTGGP +VALNNYIHSLGIDSVNIVYDEATMHQAWDNQYENYTTPRAMADLLTLFAERKVLANNTRF +YLWNAMSNLTTGSGRLRKYLPEEALLVNKTGTSGAGATNDAGVIVMPNDPLVVVAVFVKD +STEPNEVNEEIIAQIAREVYNHy +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium shandongense TaxID=1493872 RepID=A0A3G6MV88_9FLAO +-sALEQKINSIIKDKNATVGISVLGFENGFKY-NKNADKKLPMQSVFKFHIAAAVLDYVD +QGKLSLDHKILLDKTNLLEWSPLRDKYQQGNVPLSEILEYTVAKSDNNGCDIMLKLLGGT +ETVQKFMNSKGVKGFQIKFNEADMHKDWNAQYQNYSTAASATEVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGKNKLIEQLPENTPVARKTGASGTGAENEIAVVTLPNGKHYAIAVFVSN +STETDAVNCKMISDISKSAWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Cryobacterium sp. Y82 TaxID=2045017 RepID=UPI000CE3A7B4 +--AFNRRIEDLEMQSGVTIAVTAVNLGTNRRV-QHRSTDLFPMCSLFKVIAVGALVSERG +YDEQYWNTPIPFTAADIVVNSPVASKLTTLTMTPDEMADAALRFSDNTAGNLLLREIGGP +KTIARVVGSFGATATRLDRIEPELNEGLPDDPRDTTTADDMVAVLRALLVDGGAGQLARS +KLHDWMLRNSTSSTRARAGLTGSYELADKTGAGGYGIVNDAGILWQDDTDPIALCILTRT +NDPNAKGNNEVIADTTRLLVS-- +>[subseq from] EXTENDED-SPECTRUM BETA-LACTAMASE PER-1 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI000011119C +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSQTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQVAQTAYQ-- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=A0A3A0VQL2_STAGA +-----DSIEDLETTYDTTIGVYGINTQNGNEL-SHHADERFGFASTYKAIASGILLKQLT +--PQAMNQRVTIEKSDIVTYSPITEKYIGKTMTLRQLIEASMLKSDNTANNKVIQALGGV +NAFKSELRHLGDSVSEPQRLEPELNDYDPKRIADTTTPRAAATTLNRILTHPDMAKGNLQ +FMKQLMIENETGDTLIKAGANEEDIVGDKSGQGTYATRNDLAFIYPKGQQPIVLAIYTKQ +SDKNAKPNDEVIAKTAKIAIN-- +>[subseq from] Beta-lactamase n=1 Tax=Deltaproteobacteria bacterium ADurb.Bin026 TaxID=1852864 RepID=A0A1V6IDQ5_9DELT +--SLKQEIQKIISSKNATIGVAVLGNNGQDVF-SINGERHFPMQSVFKFHIGLAMLSEID +RGNFKLNQKIKIKKSELLPWSPIREKYPEGALSIAEILEYTISQSDNVGCDILLKILGGP +NFVENYIKASGVDNISIKINEEVMQNNWDRQFENWTTPLAANQILELFFLNELLSPSSYD +FLWKIMKETATGKKRLKGNLPVGTVVAHKTGWSGTAAVNDIGIVFLPDNNNFFISVFITD +SKENAEVNEKIIADISKATWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Luteibacter jiangsuensis TaxID=637577 RepID=UPI00141E7FBA +--HLRDTLAQLAERAPGTLGVTVVDMETHERT-RINADRGYPMMSVFKAPVAAAVLAEVD +AGKIALDQEVTIGRKDVVGGSPSIGAHFAGGFTVERLLVAAVSESDNTAVDALIRLLGGP +AVVTRYLRDHGIDGMRVDLSEGDVSHAFMVDVRNTTTPDAAADFLEKLWRGKLLSAASTQ +RLLRLMYDQTV-PNRLRAGLPPGVRFADKCGTSYTAAFNDIGIVTWPDGHTVIVAAFLTG +SRADAKTRNALFADIARAI---- +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter marensis TaxID=543877 RepID=A0A0G3XED2_9SPHN +--------NIVEETANGTLGVAVFDTGTGRIW-GHNDYARFPQLSSFKLSLAALVLHLDE +TGTLDAGEHISWEASELLDYAPFAKDRLEQGATLRELAEATQTLSDNTAANVLLRRLGGP +ERLTSFWRAIGDETSRLDRTEPALNDVPPGEIRDTTTPAASARTLAKLVYGDVLGDVART +TLKTWMAETRTGMRRVRAGLPPEWPAGDKTGTSFGSVYVDVGYVEPAGRAPLTFATFFRA +ARQHDPRAEGALAETGRIIAR-- +>[subseq from] Class A extended-spectrum beta-lactamase CSP-1 n=2 Tax=Capnocytophaga sputigena TaxID=1019 RepID=D5HKL4_CAPSP +-qNLKRDITKIIQGKNALVAVSVMNSKGKTEV-NINGNKKVPMLSVFKFHIALAVLDLVD +RGILDLEQNIFVKKSELLEWSPIRDKYPNGNIPLREIIEHTVSQSDNNGCDILLRLIGGV +DTVQKFIESKGIKDFAIKYNEEEMNKNGKSIYSNYTTANASSRLLQKFYNGEIISESSRD +FLFRIMYETSTGADRLISLLPPDVIVAHKTGTSGQAATNDVGIIILPDDEYYTISVFVIN +SKENTSTNEKIIADISKTVWDYy +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. CF365 TaxID=1500282 RepID=UPI0005547FF0 +---LEQKISSILKNKKATVGVSVLGFENGFTY-NKNADKKLPMQSVFKFHIAAAILNHVD +QGKLSLDQKIKLDQSNLLEWSPLRDQYPGGNIPLSEVIEYTVAKSDNNGCDILLKLLGGT +QTVQKFMDSKGVKGFQIKYNEEDMHKDWNVQYENYSTTKSAVDVLKKFYDGKLLSKKSTD +YLMKVLWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFVSN +STETDAVNCRMISDISREVWEHf +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A2W6TAA3_9FLAO +---LDQKINSIIKDKKATVGVSVLGFENGFKY-NKNADKKLPMQSVFKFHIAAAVLDFVD +KGKLSLDQKIVLDKSNLLEWSPLRDKYPNGGVPLSEVLEMTVAKSDNNGCDILLRLLGGT +QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTMNSATDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGLNKLIEQLPKNTPVARKTGASGTGAENEIAIITLPNGKHYAIAVFVSN +SMETDAVNCKMISDISKTVWDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium geocarposphaerae TaxID=1416776 RepID=A0A2M9C8T0_9FLAO +---LDQKINSIIKDKKATVGVSVLGFENGFKY-NKNADKKLPMQSVFKFHIAAAVLDFVD +KGKLSLDQKIVLDKSNLLEWSPLRDKYPNGGVPLSEVLEMTVAKSDNNGCDILLRLLGGT +QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTMNSATDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGLNKLIEQLPKNTPVARKTGASGTGAENEIAIITLPNGKHYAIAVFVSN +SMETDAVNCKMISDISKTVWDYf +>[subseq from] Beta-lactamase n=1 Tax=Pedobacter caeni TaxID=288992 RepID=A0A1M4VLZ6_9SPHI +--PLQQKLDSIVRTKKADVGFSVLYLENQKVV-SVNGDKHYPMQSVYKFHLALAVLNQVD +QGKFSIDQKILVKPSDLLQWSPIRDKYPNGNLPLSEILKYTVSESDNNGCDILFRLIGGT +GKAHQFIKKQGIKEISITGTEEEMHKDDQVQFRNWTTPKAANQLLKKFWEGKVLKKATGD +FLMKIMEETVTGPGKIKGLLPQGTVVAHKTGNSGVNGSNDIGIVTLPNGKKMLISAFVSM +TKEDDKEVDKIIAELAKAAFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter marensis TaxID=543877 RepID=UPI00069E2038 +--------NIVEETANGTLGVAVFDTGTGRIW-GHNDYARFPQLSSFKLSLAALVLHLDE +TGTLDAGEHISWEASELLDYAPFAKDRLEQGATLRELAEATQTLSDNTAANVLLRRLGGP +ERLTSFWRAIGDETSRLDRTEPALNDVPPGEIRDTTTPAASARTLAKLVYGDVLGDVART +TLKTWMAETRTGMRRVRAGLPPEWPAGDKTGTSFGSVYVDVGYVEPAGRAPLTFATFFRA +ARQHDPRAEGALAETGRIIAR-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Rhodococcus TaxID=192944 RepID=A0A0Q6GMH0_9NOCA +-eDFSTELQAVEDRYDVTVGVSLLDTGTGETI-SYRGAERFGFASTVKVFLAAEFLRRTP +--QDARDDIVRWSAADIERYSPVTTARLDTGLTAAELAEAAVRASDNTATNLVFDRIGGP +AQLDAALSRLGDDVTDIVDVEPGLNTVEPDSTANTTTADTFTANLAALRGDGSSTDADAA +TLVEWMSENATGDALVRAGAPSGWTVADKSGGAG-GVRNDIAVVTPPGRPPLVLTVLTRK +NDPSAPYEDAAVSESAAVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Koribacter versatilis (strain Ellin345) TaxID=204669 RepID=Q1IR91_KORVE +---LTKTVKTAAHPANGKVGVSAKVLDSSQTI-SFHGNKNFPMQSVYKLPIAIFTLRRVQ +EGKIKLDQVVKVDEDDLIPNSPLRDKHPRGGFTIEDLLRRAIVDSDGSASDVLLKQIGGT +REVRRYLKSQKIKGIRVQHTEEQLIENTHLQYSDSAKPDAMVDLLERLQQGKLLDTENTA +RLVGWMKETDTGKDRIRAKLPSG-TVADKTGSSGTKATNDVALVTLPNGNHFAIAIFVTD +SKADTKTRNLVIANIAHEVWSCw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A0P0GGT1_KLEPN +-------------------------------------------CSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLRDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTN--------------------- +----------------------- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dyadobacter sp. 32 TaxID=538966 RepID=UPI0011EF0E3B +---LRKHIQEIVASKNATVGVCLVSDDGDDTL-SIHGSRRFPLQSVFKYHIALAMLSQID +QGKFSLDQKVTIEKADLIPYSPIRDKYPNGALKMSEILDYTVSQSDNVGCDLLLKLLGGP +QVVEKYIKGNAINDVSIVINEQTQQSNWDLQFQNWTTPKASVAVLQKFFINKLLSPKSYD +FLWQVMKGTQTGKARLRGKLPEKTIVAHKTGSSGTAAVNDMGIVFLPNGRHFYISVFVTD +SKENAGANEKIIADVAKAAWEYf +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000FD77750 +----------------------------------------------FKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPWIRSVLPAGWFIADKTGAGERGAR---------------------- +----------------------- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. Tr-659 TaxID=2608340 RepID=UPI00141F68CE +-sALEQKISSILKNKKATVGISVSGFENGFTY-NRDADKKLPMQSVFKFHIAAAVLNAVD +HGKLSLDQKIPLNKSNLLEWSPLRDKYPDGNIPLSEVIEYTVAKSDNNGCDILLKLLGGT +QVVQKFTDSKGVKDFQIKYNEEEMHKAWNIQYENFSTTKSAVDVMRKFYDGKLLSKKSTN +YLMKVMLSTSTGLNKIIEQLPKNTPVARKTGSSGTGAENEIGIITLPNGKHYAIAVFVSN +SMETEADNCKMISDISKTVWDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Clavibacter michiganensis subsp. phaseoli TaxID=1734031 RepID=A0A399THM1_9MICO +-----------EERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRAEPDLNQAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA +LFTGWLKATQTGATLGRAELPADWTVGDKSGLGAYASRGDVAVI---------------- +----------------------- +>[subseq from] Class A beta-lactamase n=3 Tax=Cryobacterium TaxID=69578 RepID=A0A5F0D316_9MICO +--AFNRRIEDLEMQSGVTIAVTAVNLGTNRRV-QHRSTDLFPMCSLFKVIAVGALVSERG +YDEQYWNTPIPFTAADIVVNSPVASKLTTLTMTPDEMADAALRFSDNTAGNLLLREIGGP +KTIARVVGSFGATATRLDRIEPELNEGLPDDPRDTTTADDMVAVLRALLVDGGAGQLARS +KLHDWMLRNSTSSTRARAGLTGSYELADKTGAGGYGIVNDAGILWQDDTDPIALCILTRT +NDPNAKGNNDVIADTTRLLVS-- +>[subseq from] Beta-lactamase n=1 Tax=Anditalea andensis TaxID=1048983 RepID=A0A074L5V1_9BACT +---LLKEIERIVSDKDAIVGVSIIANNGKDLV-SLNGDKHFPMQSVFKFHIALAVLSEID +KGKLSLNQEIVLSKEDLLPWSPLRDENPDGGFTIAKLIQYSISQSDNTACDVLIRVIGIP +YTVEEYIKKNGIQDIGITFNEEDMQTKWENMFQNWTTPKAASMTLKRFYDNDLLTKESYD +FIWDVMKDTTTGKNRIKGQLPEETIVAHKTGWSGTAAVNNIGIVFFPSGAHFILSVFVTE +SKENFETNEKIISEIAKATYDFy +>[subseq from] Serine hydrolase n=1 Tax=Spirosoma sp. HMF3257 TaxID=2183553 RepID=A0A327NI49_9BACT +-qRLAQELESIAKLAKGKVGICALHLESGKQV-SLNLQERFPMASTVKVAIAVQLFTLIE +QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT +EAVQNRVKALGIQGMSVDRTIIQLLAKLKTDPRDTSTPEAMVNLLTQIYRGTALKPESRA +LLLGVMERCRGGAARLKSYLPPNTVIAHKTGSLDGSATDDVGIITLPGDGHIAIAVFVGD +SPMPLAEREQVIAHSARSIYDYf +>[subseq from] Serine hydrolase n=1 Tax=Scytonema hofmannii PCC 7110 TaxID=128403 RepID=A0A139WVI3_9CYAN +-------------AAQGNVGIGVLDLSTGKSW-FRNGKQRFPMQSVYKLPIAIATLKRVD +EGKFALNQPITVTRQELAPWSPITKEFKGNSFTVQNLLERSVGISDNTAADVLVRLVGGT +GQVNAILGRLKIRDVRVDRLERQLQSRYLVDPRDTATPEGIVDLLVKLQSNQLLSQKSTA +LLLKIMTDSPTGAKRLKAGLPNNWSIAHKTGSGPGTATNDVGIVSSPNGKRVAIAVFIAG +SKAPVEAREKVMSNVASAVVK-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Francisella TaxID=2610885 RepID=UPI0011B35BBA +--QISNSLHNLEKQYGGKIGVYTINRNDNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM +TNKDLLNEKIKILSNQVVGYSPITKEHINQTMTVSQLSRAAI-QSDNTATNLLIEKLGGL +SNLNKFILSLHDHATKVAGLEPIANQVNLTTNQNKTTPKIMARDINKLAFNNILDKKHRL +LFKKWLLGNDSDDNRIAAEIPDEWDVGNKTGTCAYGSTNDVAIIWPDDDRAIIMAIFYTQ +SQENAKPNSKIIREITKILLD-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium aurantiacum TaxID=2116499 RepID=UPI000D11B403 +-qDLRNKINTITSTKNATVGISVKGIEDKDTL-SINGNKETPLMSVFKFHIALAVLHRVD +EGKLKLNQKFFIKKEVLLPWSPIREEYPDGNLTLDQLLRYTVSHSDNNGCDILLNIIGGT +DSVQKFINQQGIKDFTIKVNEQQMSS-FDKFYLNTTTPLATTDLLEKFYKGKVLKKETTK +YLYQIMVETSRGLTWMKAGLPAGTEVAHRTGISSRAAMNDVGIVKLPNGKHFILSVYLKN +INEEMADTEKIIADISNAVWEYy +>[subseq from] Beta-lactamase n=1 Tax=Aeromonas caviae TaxID=648 RepID=D7P3C9_AERCA +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQVAQTAYQ-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=25 Tax=Proteobacteria TaxID=1224 RepID=BLE1_PSEAI +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQVAQTAYQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Larkinella arboricola TaxID=643671 RepID=A0A327X7X7_9BACT +-qRLNQELERIAKLAKGKVGLCAVHLESGQRI-SLNVQEKFPMASTVKVAIAVELFNKIE +KGELSLRTMVELKPSDLHPGSGTLETLFAKPLSVENLLELMMVISDNSATDILLNLVGGV +EPVRARLKTLGIEGMSVDRTIVQLIAKLEQDPRDTSTPEAMVNLLTQIYQAKALKPENRD +LLLAVMERCRGGLARIKGFLPPETVVAHKTGSLNSSATDDVGIITLPGDGHIAIAVFITS +SAQPLAEREQTIAHLSRTVYDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=T1Z1E9_ECOLX +------------------------------------------------------------ +-EPNLVNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTTDIAVIWPKDRAPLILV----- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SFT5_9BACT +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTL---- +------------------------------------------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Erythromicrobium ramosum TaxID=35811 RepID=UPI0013267C31 +--QLAAELRIIEAAGDGTLGVELFDTVSGMSV-GLNRDRRFGHASSFKFSLAALLLQRHA +AGQIDADKRVTWTEADMLEYAPFTRERIGAGATLRELARATQTTSDNPAANILLRNLGGP +AGLTAFWRSMGDEVSRVDRYEPEMNIVPPAEFRDTATPAAMARNVAKIIYGDVLPEAERA +ELKGWMIATETGLRRVRAGLPEGWVAGDKTGTSGEGNYIDIGFAEGPKGPPITFACYFRA +RQAEAARAELTLSRVGRII---- +>[subseq from] Beta-lactamase n=1 Tax=Rufibacter glacialis TaxID=1259555 RepID=A0A5M8QA90_9BACT +-eSLRDKIYQIASAKNATVGVSIMGSNGNDTL-SLNGENRFPMQSVFKFHIALAVLSQID +QGRLSLDQKIKIQKKDLLPHSPLREKYPNGALPLSEVLSYTVSSSDNVGCDALLRLLGGP +QEVERYFVRNNFQDISIKINEEVMQNNWDLQFQNWTTPNAASKVLKSYYHEKLLSQKSHD +FVWKEMRETETGKNRLKGQLPKGTVVAHKTGSSGTAAVNDIGVVFLPNGEYYFISVFASN +SNEDLPTNEKIIADISKAAWDYf +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhodococcus TaxID=192944 RepID=UPI00138F8355 +-eDFSTELQAVEDRYDVTVGVSLLDTGTGETI-SYRGAERFGFASTVKVFLAAEFLRRTP +--QDARDDIVRWSAADIERYSPVTTARLDTGLTAAELAEAAVRASDNTATNLVFDRIGGP +AQLDAALSRLGDDVTDIVDVEPGLNTVEPDSTANTTTADTFTANLAALRGDGSSTDADAA +TLVEWMSENATGDALVRAGAPSGWTVADKSGGAG-GVRNDIAVVTPPGRPPLVLTVLTRK +NDPSAPYEDAAVSESAAVVLN-- +>[subseq from] Class A beta-lactamase n=1 Tax=Shewanella maritima TaxID=2520507 RepID=A0A411PDM4_9GAMM +--SLNTDIKSLLDSKQATVGVSIWDQNANPIV-AINADNQLPMQSVFKFHLAAAVLHQVD +QGKWSLADKITITPDDLDNWSPIRKKYPTGALTLAQVIKYTVAVSDNVGCDVLIGMLGGP +KVLEQYLHQAGIKDIAVKYNEEMMQQVWQRQFDNWTTANGANQALSKLYDEQLLSATSHR +FLWDVMKSSKTGKNKIRAGVRQGTIVAHKTGYSGKHAHNDIGIVFLPNGSHYYISILVSD +SRESSDDSQKIIADISKLAWMHf +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR485 TaxID=1500294 RepID=UPI0006481857 +---LEQKINSILKNKKATVGISVLGFENGFTY-DKNADKKLPMQSVFKFHIAAAVLNAVD +QGKLSLDQKIVLNKSNLLEWSPLRDKYPDGNIPLSEVIEYTVAKSDNNGCDILLKLLGGT +QPVQRFMDSKGVKGFQIKYNEEAMHKDWKVQYENYSTTKSAVNVLKKFYDGKLLSKKSTD +YLMQVMLSTSTGLNKMVEQLPKSTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN +SMETDAVNCRMISDISKEVWEYf +>[subseq from] Beta-lactamase class A n=2 Tax=Parapedobacter luteus TaxID=623280 RepID=A0A1T5BWG6_9SPHI +--TLRRQIAQIADSKDAVVGVAITGRDGQDTL-SVYGSRRFPMQSVFKFPIAVAMLSEVD +KGTFSLDQKITIKKSELLPYSPIRETYPEGALTIAEILRYTVSLSDNVGCDVLLRLLGSP +QVVERYFHERSFKEISIKINEEIMQGDWEAQFRNWTTPNEANRILQACYEDNLLSPESYD +FLWGLMKTTETGKNRLKGQLPEGTVVAHKTGWSGTAAVNNIGVVFLPDGNYFYISVFVTD +SKEDLETNERIIADIAKAAWDYf +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus sp. NAM3COL9 TaxID=1667172 RepID=A0A0Q9Y1X5_9STAP +----ANEFDKIEKDNNTTVGVYGINTENGKKV-RHNANERFAFASTFKATASGVLLNNYS +--EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMKEIGGV +KAFKHELKQLGDNISNPQRLEPELNLYNPNSTADTTTPRAAAEILNTLLTSSQISDGNLD +LLKQVMIENETGDSLIKAGAADNYIVGDKSGQGTYATRNDLAFIYPNKHKPIILAIYTKQ +DDKDGQPDDKVIADAAKEAIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma sp. HMF4905 TaxID=2682092 RepID=UPI0012F7F425 +-qRLEQELESIAKLAKGKVGVCALHLESGKQI-SLNVQERFPMASTVKVAIAVQLFTLIE +QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT +EAVQNRVKALGIKGMSVDRTIIQLLAKLITDPRDTSTPEAMVNLLAQIYRGTALKPESRA +LLLGVMERCRGGAARLKGYLPPNTIIAHKTGSLDGSATDDVGIITLPGDGHIAIAVFVGD +SPMPTAEREQVIAHSARSIYDYf +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. StRB126 TaxID=878220 RepID=A0A077KL18_9FLAO +-qDLRSKINTIISTKNATVGVSLKGIEDKDTL-SINGNKAMPMLSIFKFHIALAVLNQID +KGKLKLDQKFLIKKEELLPWSPIREEYPAGNLTLDQLLRYTVSHSDNNGCDILLKMVGGA +PAVQKFINQQGIKDFTIRLNEQQMNTF-ESYFVNTSTPLATTDLLEKFYKGKVLKKETTK +YLYQIMVETSRGLTWMKAGFPAGTELAHRTGISGRAAMNDVGIVKLPNGKHFILSVYLKN +SNEEMKDTEKIIADIGNAVWEYy +>[subseq from] Class A beta-lactamase n=1 Tax=Dyadobacter sp. AR-3-8 TaxID=2576211 RepID=A0A4U6D890_9BACT +--RLDHELGRIAKLAKGKVGVSAVHLETGKHI-SLNLKELFPMASTIKVAIAVQLFTKIE +KGELSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT +KAVQERMNALGIKGMSIDRTIIQLIARLQKDPRDTSSPEAMVNLLTQIYNGMALKPESRE +LLLGVMERCRGGVARLKGYLPTGTVIAHKTGSLNASATDDVGIITLPDGGHVAIAIFVAE +SGAELAEREQTIAHISRSIYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Klenkia soli TaxID=1052260 RepID=UPI000B83509A +--DVSAELAALEQEYDVRIGVSAVDTGTGTRV-EHRADERFGYASTLKAFAAGVFLREVP +--SADRARLVTWSQTDVDAYAPVTGAAVATGLTAAELAEAAVRQSDNLALNLVLDLLGGP +AGLDAALADLGDTTTDVVHEEPALNDVDPASTADTTTPAAFTDGLRALLAPGALTDADRS +TLLSWMSGNATGDTLVRAGAPAGWVVADKSGGAG-GIRNDIAVVTPPGRDPVLVTVLTEE +LDPTAAYEDAVVARTAAAVL--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A649UHJ9_ACIBA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHNSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASR- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D5C9D4_ECOLX +---------------------------------------------TSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNHI------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Stenotrophomonas ginsengisoli TaxID=336566 RepID=A0A0R0DGQ7_9GAMM +---LQHEAQRLVAMLPGEVGVSMLHLQSGRAV-HVNGERAFPLASVMKVPVAVHILTLVD +EGKLRLDQNVVIGPNDIYPGGPMQIH-LTPGISVRDLLHMMITVSDNNATDMLVKLGGGT +DAVTQRMRQLGINDVRIDRYIWELLAAWNRDPRDSGTTTAMAQLLASVWKGQVLSDNSTA +VLKAIMGQTRTGAGRLRGVLPPDTPVAHKTGTVGD-VINDVGVITLPDGKGEVIVAVLME +STADTAQRERVIANLARAAHDYf +>[subseq from] Beta-lactamase n=1 Tax=Klenkia soli TaxID=1052260 RepID=A0A1H0UJ68_9ACTN +--DVSAELAALEQEYDVRIGVSAVDTGTGTRV-EHRADERFGYASTLKAFAAGVFLREVP +--SADRARLVTWSQTDVDAYAPVTGAAVATGLTAAELAEAAVRQSDNLALNLVLDLLGGP +AGLDAALADLGDTTTDVVHEEPALNDVDPASTADTTTPAAFTDGLRALLAPGALTDADRS +TLLSWMSGNATGDTLVRAGAPAGWVVADKSGGAG-GIRNDIAVVTPPGRDPVLVTVLTEE +LDPTAAYEDAVVARTAAAVL--- +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. CH25 TaxID=713559 RepID=A0A4Q1FNU4_9FLAO +-sDLEQKINSITKGKQATIGVSVLGFENNFKY-SQNGDKKLPMMSVFKFHVACAALDLVD +KGRLSLDQKVFIKKSELYNWSPFRKKYPEGNITLSEVIDYTVALSDNNLCDILIDLVGGT +QTVQKYMDSKGVKDFQIKHSERGMANGWDSLYENYTTTNSTVQLLKKFYDGKLLSKKSTD +YLMNIMLGTQTGTNKLVEQLPKGTPTAHKTGSSSTIAENDMGIITLPNGKHYAITVYVSN +SKESEAENCKIISNISKAVWDNf +>[subseq from] Serine hydrolase n=1 Tax=Spirosoma pollinicola TaxID=2057025 RepID=A0A2K8Z1G4_9BACT +-qRLNQELERIAALAKGQVGICALHLESGKQV-SLNLQERFPMASTVKVAIAVQLFTLIE +QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT +QAVQNRLKTLGIQGMSVDRTIIQLIARLKIDPRDTSTPDAMVNLLTQIYRGTALKPESRA +LLLGVMERCRGGAARLKGYLPPNTVIAHKTGSLDGSATDDVGIITLPGDGHIAIAVFVGD +SPMPLAEREQTIAHAARSIYDYf +>[subseq from] Beta-lactamase n=1 Tax=Filimonas sp. YR581 TaxID=2135469 RepID=A0A2U0ZQS5_9BACT +---LREKMAAVAARSGGVVGIAVTNLDTRDTF-TLNNEPVYPMQSVFKFPIAMAILHLID +GGKLAPEQKIFIGKNKMVKYSPLRDSFPAGNQTIAQLLQYSVSKSDNIACDLLIELAGGE +AAVNDYIHSLGVQQISIVASEAKMHANWNTQYKNWCAPSALVQLLDIMNQGKALSKTSND +FLWKLMLETTTGKKRLKALLPAGTEVAHKTGLSDTAATNDVGIILLPNGQKLAVAVFVMN +SKANEAVREATIAEVAKLAYDH- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. ERG5 TaxID=1381597 RepID=UPI00054BED58 +--RLTAEFARLAKQTDGTVGVAVQRVDGNART-TLNGGTNFPMASTFKIAVAGTILARID +KGELTLDQMIAVDPAVIVESEGIAEQTPHPGLSIHNLLELMLTRSDNTATDVLTALAGSP +VAVTAWVRKLGVTGQQIDADTAHIIYSFNDDPRDSSTPEAMLDLLLKIQSGKALSATSTK +ALLDIMERCHTGEARLKGRLPLGTVVAHKTGTLMS-IANDVGLVTLPDGSKFAIAVFVKG +DTKGTAVQERVIADIARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Francisella marina TaxID=2249302 RepID=A0A5C2BWA5_9GAMM +--QISNSLHNLEKQYGGKIGVYTINRNDNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM +TNKDLLNEKIKILSNQVVGYSPITKEHINQTMTVSQLSRAAI-QSDNTATNLLIEKLGGL +SKLNKFILSLHDHATKVAGLEPIANQVNLTTNQNKTTPKIMARDINKLAFNNILDKKHRL +LFKKWLLGNDSDDNRIAAEIPDEWDVGNKTGTCAYGSTNDVAIIWPDDDRAIIMAIFYTQ +SQENAKPNSKIIREVTKILLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus stepanovicii TaxID=643214 RepID=M9TM58_9STAP +------DIEKIEKKYGANVGMYALNTQNGKEL-SFNENKRFAYASTLKTISSAMLLEQTP +--YNKLDKKIHINKDDIVPYSPVLEKYIGKKITLKKLIEATMLVSDNTANNKIIDELGGY +EQVKTRLIDLGDSTTHPSRKEPNLNYYSPKDKRDTSTPLAYGKTLKKLISDGNLSKANKD +FLLDLMFKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVAFVYPDGQKPIILVIFTNK +DRKDGKPNDKIVS---------- +>[subseq from] class A beta-lactamase n=1 Tax=Francisella sp. SYW-2 TaxID=2610886 RepID=UPI00123D0B7F +--QISNSLHNLEKQYGGKIGVYTINRNDNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM +TNKDLLNEKIKILSNQVVGYSPITKEHINQTMTVSQLSRAAI-QSDNTATNLLIEKLGGL +SKLNKFILSLHDHATKVAGLEPIANQVNLTTNQNKTTPKIMARDINKLAFNNILDKKHRL +LFKKWLLGNDSDDNRIAAEIPDEWDVGNKTGTCAYGSTNDVAIIWPDDDRAIIMAIFYTQ +SQENAKPNSKIIREVTKILLD-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. xlx-214 TaxID=2654325 RepID=UPI0013D8A5D3 +-nELKQKIQQIIWTKNVEVGVAISGNNNKDTL-SIHGNDRFPLQSVFKFHIAIAVLSEID +KGNLSFNQKIKIEKKDLIPYSPIRDKYPNGTLPLSKIIEYTVSQSDNVGCDLLLKLIGGP +KAVEEYFIKNGIKDVSIKINEEVQQANWDLQFENWTTPKAANEVLSTFYYAKLLSEKSYN +FLWKTMKGTETGKARLRGQLPENTIVAHKTGSSGTAAVNDIGIVFLPNGNHYFISIFLTK +SYENDETNEKIIADISKATWNYf +>[subseq from] Class A beta-lactamase n=2 Tax=Chryseobacterium indologenes TaxID=253 RepID=A0A0N0IXR3_9FLAO +-eNLRKEIIRIINAKNATAGISIKNIENKDTL-SINGQMSMPMMSVFKFHIALAVLDQVD +KGKLKLHQKFLIKKEELLPWSPIRDEFPDGNLTLDQLLRYTVSHSDNNGCDILLRMMGGP +QTVQKFINKQGIKDITIKLDEEEMAKAWENLYVNVTTPEATTLLLEKFYKGKVLKKNTTD +YLYRIMVQTSRGLTWMKAGLPSGTELAHRTGISGRAAMNDVGIFKLPNGQHIILSVYLKN +ITEERADTEKIIADIAHAAYTHy +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium shandongense TaxID=1493872 RepID=A0A3G6Q6Z2_9FLAO +-sALEQKINSIIKDKNATVGISVLGFENGFKY-NKNADKKLPMQSVFKFHIAAAVLDYVD +QGKLSLDHKILLDKTNLLEWSPLRDKYQQGNVPLSEILEYTVAKSDNNGCDIMLKLLGGT +ETVQKFMNSKGMKGFQIKFNEADMHKDWNAQYQNYSTAASATEVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGKNKLIEQLPENTPVARKTGASGTGAENEIAVVTLPNGKHYAIAVFVSN +STETDAINCKMISDISKSAWDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Eisenibacter elegans TaxID=997 RepID=UPI00041B25B4 +--NLETRLAEIVRGKQATVGVAILGLGGQDTL-LLNGYERLPMQSVFKFHIGIVMMAAID +EGRFTLDQPIKIRKRDLLPYSPIRDAHLKGALPVREILQYTIALSDNVGCDILLRLLGGP +AEVERYFHQRGFEALAIKINEETMQANWELQFQNWTTPLEATRVLAAFYNQPYLSPQSYD +TLWQIMTSTKTGQQRLKGQLPTGTAVAHKTGWSGTAATNDIGVISLPNGQPLFISVFVAD +SKEDNATNEAIIAQIAEAAWDYy +>[subseq from] class A beta-lactamase n=1 Tax=Marimonas sp. GH1-19 TaxID=2545756 RepID=UPI0010F5CCA4 +---VGAAIERVATQLAGRIGFAAQEIGGGDVI-AFNGDEAFAMASTYKVAIAAAVLDRVD +KGELSLDQMVDVTLDMMMIGDAALNTHPGLQLSIANVIEVMITESDNTATDISMGLAGGP +AAVTQYLRRIGISDIRVDRPTGEIIGDFEADPRDQATPLAMLQLLLAIDSGAATSAESRD +FLIDVMSRTRTGAGRLKGLLPRGTPVANKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS +SATSEADRDRAIAEVTRSLFDYf +>[subseq from] class A beta-lactamase n=1 Tax=Francisella sp. XLW-1 TaxID=2610887 RepID=UPI00123E2AF4 +--QISNSLHNLEKQYGGKIGVYTINRNDNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM +TNKDLLNEKIKILSNQVVGYSPITKEHINQTMTVSQLSRAAI-QSDNTATNLLIEKLGGL +SNLNKFILSLHDHATKVAGLEPIANQVNLTTNQNKTTPKIMARDINKLAFNNILDKKHRL +LFKKWLLGNDSDDNRIAAEIPDEWDVGNKTGTCAYGSTNDVAIIWPDDDRAIIMAIFYTQ +SQENAKPNSKIIREVTKILLD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Agromyces sp. OV568 TaxID=2135465 RepID=A0A3E0I529_9MICO +hrRLSDAIAELERATSVTIGVTAIWHDSRRAF-RYRGDQRFPMCSVFKTLAAGALVQARG +YDEAYWAGPIPFTSADVVGDSTKLDTT-TWTATPEQMADAALRFSDNTAGNLLLRELGGP +QAVTAFARSLGATRTRLDRPEPEVNEATPGDERDTSTPDDIAFLLQKLLIDQGAGALTTA +RLQEWMLRNTTSGKRILAGLTPPFELADKTGLGGYGVVNDAGVIWRPGEEALTLAILTRT +DRADAPSNHDVLADVTRLVVA-- +>[subseq from] Uncharacterized protein n=1 Tax=Pelomonas sp. Root1217 TaxID=1736430 RepID=A0A0Q6TF25_9BURK +---TATDFVALERRVQGRIGFFAIDTGSGRVM-AHRADERFATASTFKILLAARVAQGVE +AGRWGWNDAVPLRASERVPHSPAFDRLLPRGATLAELVQGIVVESDNPCANVLLRHCDSP +SGLTAWLRQQGDAVTRLDRFETELNENAPGDPRDTSTPRAFARTLQHLLLGPGLKRANQA +RLWADLQASRTGLQRLRAGVPASWRVIDKTGSGGRGAVNDVALVFPPSRSPWVVVAFQSD +SKASTDELSGVHAAAMRGLVRAw +>[subseq from] class A beta-lactamase n=2 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000B049B73 +--TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNESNLS +LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. 2VB TaxID=2502204 RepID=UPI0010F9381C +---LEQKINSILKNKKATVGVSVLGFENGFTY-NKNADKKLPMQSVFKFHIAAAVLNAID +QGKLSLDQKIKLDQSNLLEWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLRLLGGT +QTVQKFMDSKGVQGFQIKYNEEDMHKDWNVQYENYSTTKSAVDILKKFYDGKLLSKKSTD +YLMKVLWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFVSN +STETDAVNCRMISDISREVWEYf +>[subseq from] Beta-lactamase n=1 Tax=Sulfitobacter sp. JL08 TaxID=2070369 RepID=A0A345RHD3_9RHOB +--SVGAAIEQIASGLAGRIGFAAQEIGGNEVI-AFNGDETFAMASTYKVAIAAAVLDRVD +RGELSLDQLVEVPPDMFVTVFALAETFPHPGLSVANLIEVMITESDNTTTDVSMELAGGA +AAVTEYLRNLGITDIRVDRTTREILMDFEADPRDHATPLAMLQLLLAIDGGTAMSPESRE +FLLGVMSRTRSGPGRLKGLMPKGTLVAHKTGTAG-GIANDVGYITLPDGRRFAIAVYTNS +NETPVADRDRAIAEIARMMFDYf +>[subseq from] class A beta-lactamase n=1 Tax=Asaia bogorensis TaxID=91915 RepID=UPI0011BEC1D0 +---------RYEKLSGGRLGVHIFCPESGTAL-SWRGEERFRMCSSFKASLAACVLACCD +RDEDDLTRRIAFRESDFKEWAPVAARNRDAGLSLAALCAGAVTMSDNICANMLLRHIGGP +AALTRFWRDSGDEITRLDAYEPELNRPSANPDDNTTSPVAMARTLHRLIHGTLLHPNSAA +LLRSWMINCTTGTQRLRAGLPAHWVVGDKTGNNGKDIAADIAFASADAGKSVIIATYTAG +GTPDETQFRRVFHDIGALA---- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingobium phenoxybenzoativorans TaxID=1592790 RepID=UPI00087314E2 +-dSLRAEFARFAAMTDGTVGIAVRRIGDDHAV-MLNGNTLFPMASTYKVAVAGAILAQVD +RGRVTLDTMIPVDRSMMVSGIADMMPHPGLSLSVYNLLELMLTRSDNSATDVLVKQAGGP +QAITGWLRSVGIRDQRVDGNTAQLLYAFAADPRDTSTPEAMLDLLTRIAQGRALKPDTTR +TLLDIMARCHTGQNRLKALLPPGTPVAHKTGTLN-GLANDVGVVTLPDGSAMAIAVFVMK +DSKGRDVRDRIMAEAARAAHDYy +>[subseq from] class A beta-lactamase n=1 Tax=Bosea sp. WAO TaxID=406341 RepID=UPI0009F89F9B +--KLDAGIKSIEQAAKGRVGVALLDLRDRKSW-SHRGAEPFPLQSVFKLPLAIAVLQAVE +AGKLKLDQKITVTRNDLSLHSPLARAFKGERYTLRDLLTRSTGESDNTAADLLLRLIGGP +QVLTAMLKDGGVPGISVDRYERVFQPATLKDKRDAASPDASAAFLEALARGNWLREAHTA +LLDKIIVETKSGPQRIRAGLPQGARFAHKTGLGPNHATNDIGIVTLPDGRRFVIAVYLAG +SQASAEAREAAHAAVARLAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000AA34C63 +--TFAKDIEQIENEYNTKVGVYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS +LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter sp. HKB08 TaxID=2502843 RepID=UPI001008ADB2 +----ASRLRIVEATANGTLGVAIYDTGSGALT-SYNGFARFPHCSSFKLSLAAFVLKLGT +DGGMDLSEKVDWDAAALLGHSPFTRERLATGATIRELAEAAQKQSDNTATNILLERIGGP +QGMTAFWRAIGDPTSRLDRYELELNNVPAGEIMDTTSADAMALTVGRLTHGDVLAEDDAA +TLRQWMVDTATGLDRVRAGLPPEWRAGDKTGTSLRSVYVDIGFVEPPDRAPLTFAAYYRA +NRKADPASLAVLADVGRVITQ-- +>[subseq from] Beta-lactamase class A n=2 Tax=Erythrobacteraceae TaxID=335929 RepID=A0A0P7YLZ1_9SPHN +---MQASLRLIEAKAGGTLGVEIHETATGVSV-GLNRDRRFGHCSSFKLSLAAMVLALDA +AGEIDANRRVTWTKGDLMPVSPFTERRLAEGATLLELAEYTQKYSDNAAANILLRELGGP +AALTGFWRSIGDGESRLDRYEPELNNVPVTEYRDTTTPAAMARTVAKLAYGDVMPEAERA +RLRQWMIDTPTGARRVRAGLPESWIAGDKTGTSIGSSYVDIGFARPPEHPPVTFAAYYRA +RETHDEGSEAALASVGEVI---- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium culicis TaxID=680127 RepID=A0A1H6HIX3_9FLAO +--RLEQKINSILKNKKATVAVSVLGFENGFTY-DKNADKKLPMQSVFKFHIAAAVLDAAD +KGKLSLDQKIKLDHSNLLEWSPLRDQYAGKEIPLSEVIEYTVAKSDNNGCDILLRLLGGT +QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTTRSAADVLKKFYDGKLLSKKSTD +YLMKVMQSTSTGLNKMVEQLPENTPVARKTGASGTGAENEIGIVTLPNGRHYALAVFVSN +STETDTVNCRMISDISKEVWEYf +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium mulctrae TaxID=2576777 RepID=UPI00111690BB +---LAHKVDSIVKDKKATVGVSVLGFEDGFKY-NKNATTKLPMLSVFKFHIAAAVLDLVD +KGKLSLDQKILIKKSDLLEWSPIREKYPNGNLPLSEIINYTVAWSDNNGCDVLLRLIGGT +QVVQKFMDSKGVKDFQIKHNEEQMHKGAKYLYENYTTTNSLSQLYKKFYDGKILSEKSTK +FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN +STETDDVNCKMISDISKAVWDHf +>[subseq from] Beta-lactamase n=1 Tax=Francisella sp. FSC1006 TaxID=1547445 RepID=A0A097ELS9_9GAMM +---TSNEIKKIEKEYGGKIGVYTINRNDWKNF-SHNASFYFPTCSTYKFLVVGAILKQSM +KNKELLSEKIKIVDNQIVGYSPITKKHSNKEMTIRQLCKASIN-NDNTATNLLIHKLGGL +KELRKFTLSLQDHATKVADLAPKISKVDLTTNLNKTTPKIMARDINKLAFNDVLDDRHQA +LFKKWLRESTSGDNRIAAEIPEDWTIGDKTGTCEYGTTNDVAIIWPDDSKPIAMSIFYTQ +PEKSAEPNSKVLRKVTEILFD-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Rudanella sp. HX-22-17 TaxID=2614655 RepID=UPI001261E911 +---LRAEIQQIVADKKAVVGVSIIANDGKDTL-SLNGDRRCPLQSVFKLHIGLAVLSQVD +KGRFTLDQTVEVRKADLVPWSPLRDENPNGGFTIARLIQYAVSQSDNVACDVLIRLLGSP +KAVETYIKENGVEEIAIRFAEKEMQAEWDNMFQNWTTPKAASKTLQIFYDGKRLSKRSYD +FIWQTLRETGTGVNRLKGRLPAGTVVAHKTGSSGTAATNDIGLLFLPNGEFVIISVFVTD +SKENEATNEKLIADIAKATYDFy +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma aerolatum TaxID=1211326 RepID=UPI0009ADDD66 +-kRLERELERISTLAKGKVGICALHLESGKQV-SLNVQERFPMASTIKVAIAVQLFTLIE +QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT +EAVQKRVNALGIQGMSVDRTIIQLLAKLATDPRDTATPEAMVNLLAQIYRGTALKSESRA +LLLGVMERCRGGAARLKGYLPPNTVIAHKTGSLNNLATDDVGIITLPDEGHIAIAVFVGD +SPMPLAEREQVIAQSARAIYDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. YR221 TaxID=1500293 RepID=A0A1W2DQD6_9FLAO +-eRLRKEIQQIIASKNATVGISIKNIEDKDTL-SINGNSMMPMMSVFKFHIALAVLDQVD +KGKLKLNQKFFIKKEDLLPWSPIQEEFPNGNLTLDQLLKYTVSHSDNNGCDILLRILGGT +EPVQKFINQQGIKDFTIKVNEQQMS-NWDNLYLNVTTPIATTALLEKFYNGKVLKENTSQ +YLYRIMTETSRGLTWMKAGLPDHTELAHRTGISSRAAMNDVGIFKLPNGKHIILSVYLKN +ITEERTDTEKLIADIARATYNYy +>[subseq from] class A beta-lactamase n=1 Tax=Pelomonas sp. Root1217 TaxID=1736430 RepID=UPI00070D22E7 +---TATDFVALERRVQGRIGFFAIDTGSGRVM-AHRADERFATASTFKILLAARVAQGVE +AGRWGWNDAVPLRASERVPHSPAFDRLLPRGATLAELVQGIVVESDNPCANVLLRHCDSP +SGLTAWLRQQGDAVTRLDRFETELNENAPGDPRDTSTPRAFARTLQHLLLGPGLKRANQA +RLWADLQASRTGLQRLRAGVPASWRVIDKTGSGGRGAVNDVALVFPPSRSPWVVVAFQSD +SKASTDELSGVHAAAMRGLVRAw +>[subseq from] Beta-lactamase n=1 Tax=Syntrophaceae bacterium PtaB.Bin038 TaxID=1811716 RepID=A0A1V4X7F0_9DELT +---VAAEIGRIEKAARGTLGVAAVHLETGRKV-EYRAEEFFPMASTVKVPLAARILDMAD +RGQVGLATEIPVKKMEMNPEGPLAAIRWRPGRSIEELLEAMITRSDNTATDVLFRVAGGP +AAVEAWLKGMGLKDIRPARYIRELLRGYDADPRDQATPRAMLALLVKIRLADGVSAAVRS +TLIPMMERTETGTKRIRGRLPAGTVVGDKTGTLA-GTANDVGYVTLPGGGCIALVVFVKG +SEAAPAARETAIADTARLVYDYf +>[subseq from] Serine hydrolase n=1 Tax=Cytophagales bacterium TaxID=2053541 RepID=A0A521GD05_9BACT +------FIDGLSTKVQGRIGMSALLIETGETV-GYKADERFPMQSVYKFPIGMAALYAVD +QGILKLDKSVKVANEEYVSHSPLRDGNPDGAVTVKELLRLAVSESDGTASDVLMRLVGGA +QSVMNYLQAIGITGVIVKNTEKELGATNSVQYDNWATPIQATLLLKQFQLGKGLSVSSRA +LLMQLMTDTQTGLQRLKGNLPPGTVVAHKTGTSGTAATNDIGIITLPNGRHIAIAVFVTD +AKADQTTREGAIAQIARKVWEKy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A3D3MAG5_9FLAO +-kDLRNKIHEIISTKNATVGVSLKGIEDQDTL-SINGNKNTPLMSVFKFHIALAVLNHVD +KGKLKLDQKFFIKKEELLPWSPIRDEYPQGNLTLDQLLRYTVSHSDNNGCDILLNILGGT +QTVQKFINQQGIKDFTIKVNEQQMSS-FDKFYLNTTTPLATTAILEKFYNGKVLKKETTK +YLYRIMLETSRGLTWMKAGLPEGTELAHRTGISSRAAMNDVGIVTLPNGKHYILSVYLKN +ITEEMKDTEKIIADISRVVWEYy +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. SN22 TaxID=2606431 RepID=A0A5A8AK04_9FLAO +---PDSKINSIIQDKKATVGISVLGFENGFKY-DKNGDQKLPMQSVFKFHIAAAVLDFVD +HGKLSMDQKVSLSASNLLPWSPLRDKYSTGSVPLSEIIEYTVAKSDNNGCDILLKLLGGT +KTVQKFMDSKGVKGFQIKYNEAEMHRDWNAQYKNYSTAVSATEVLKKLYDGKLLSKKSTE +YLMDVMLSTSTGMNKLVGQLPKGTPVARKTGASGTGAENEIAIVTLPDGKHYAIAVFVSN +STETQEVNCKMISDISKSVWDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A3D0WHR7_9SPHN +-qDLAARISEIEKASGGRLGLGLHSPDKGLVY-AYRGDERFAMCSTFKLALAAMTLDTPG +----LREKRLHFGAGDILSYAPYAKERASSGMSGLEAAHHAVTLSDNTAANLLLAEVGGP +DGFTRWLRSMGDETTRLDRNEPALNENAPGDPRDTTTPTAHADLVGALLWGDRLAPADRA +LLEEWLVETTTGMNRLRAGLPGEWRAGDKTGTCGQGEVNDIAMFETPDGSRYILAAYLDR +AD--------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas ginsengisoli TaxID=336566 RepID=UPI0009F953E6 +---LQHEAQRLVAMLPGEVGVSMLHLQSGRAV-HVNGERAFPLASVMKVPVAVHILTLVD +EGKLRLDQNVVIGPNDIYPGGPMQIH-LTPGISVRDLLHMMITVSDNNATDMLVKLGGGT +DAVTQRMRQLGINDVRIDRYIWELLAAWNRDPRDSGTTTAMAQLLASVWKGQVLSDNSTA +VLKAIMGQTRTGAGRLRGVLPPDTPVAHKTGTVGD-VINDVGVITLPDGKGEVIVAVLME +STADTAQRERVIANLARAAHDYf +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Methanosarcina mazei TaxID=2209 RepID=A0A0F8GV64_METMZ +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLT----- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Runella sp. YX9 TaxID=2282308 RepID=A0A369I915_9BACT +---LRQKIQQIASKTDGTLGVGILGLENRDTL-TLNNHVHFAMQSVYKFHLGLAILNQVD +KGNLKLNQKILIQKKDLLPWSPLREKYPNGNIPLSELIQFTVAQSDNNGCDILFRIMGGP +RVVDNYIKSIGMTDVSIRTTEEEMHKTEGAQFTNWTTPWSAVQLLEKFYQKKILSPASHA +FMWKVLTEANTGSGKIKGLLPAGTLVAHKSGLSGTAATNDIGIVTLPNGKHFIISIFYGN +TKLSDKESDKVIAEVTKAAWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma sp. BT328 TaxID=2692134 RepID=UPI001410024F +--SLHNQIEQIAGAAQGRVGVAAMLLETGESV-ALLGDQRFPMQSVYKMPIGMAVLHLVD +QGKVTLDQKVRVETIEYVSHSPMRDQFPKGTISVAELLRYSVSESDGSASDVLMRLAGGP +KPIMAYFKSLGIKDIIIANTEKEIGGDNAVQYRNWAKPTEVVALLRLFQQGRGLSNSSRA +LLLRLMTETETGLHRLKGQLPAGTVVAHKTGTSWTAATNDVGLITLPTGQHIALAVFVSD +SKADEKTREAVIAQIALATWNFw +>[subseq from] class A beta-lactamase n=1 Tax=Dyadobacter sp. 32 TaxID=538966 RepID=UPI0011F04D52 +--RLQNELERIAGLAKGKVGVSAVHLESGKTV-NLNPREAFPMASTVKVAIAVTLFTKIE +KGELSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGV +SAVRARLSALGIQGMSVDRTIIELLAKLQADPRDTSTPEAMVNLLSQIHSGKALNPESTA +LLLGVMERCRGGLARLKGYLPPGTVVAHKTGSLDANATDDVGIITLPDNGHIAIAVFIGK +SSQPLAEREQTIAHLTRSIYDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. POL2 TaxID=2713414 RepID=UPI0013E0F516 +-qDLKTSIQTILKDKKANVGVAVWHLEKQDTL-SVNGHRHLPMQSVFKLPIGLAVLDLVD +KGKFKIDQKIKFTKAEMMPHSPMRDAYPEGGLTVREMLKYVVANSDNNTCDILLDRIGGP +EVVQKYMDKIGIKDFQIVSNERIMHETPSFQYQNYWNANSANDLLNKLYTKPILKEASKK +EIIKILEETNTGLNRLKAELPVGTIVAHKTGSSATAATNDIGVITLPNKEHMIVSVFVSD +SYENDATNEKIIADIAKASFDYy +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. AG844 TaxID=2183998 RepID=A0A2V2ZM90_9FLAO +---LEQKINSILKNKKATVGVSVLGFENGFTY-NKNADKKLPMQSVFKFHIAAAVLNAID +QGKLSLDQKIKLDQSNLLEWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLRLLGGT +QTVQKFMDSKGVQGFQIKYNEEDMHKDWNVQYENYSTTKSAVDILKKFYDGKILSKKSTD +YLMKVLWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFVSN +STETDAVNCRMISDISREVWEYf +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WZQ0_9BACT +--RLQERLNNLDSSAQGDVGIGVLDLDTGERW-FRNGKQRFPMQSVFKLPVGIVVLKLVD +EGKLSLNQTVTITREQFVPWSPILKEIKGDRFTVQYLLQRAVGDSDNTAADALVRLVGGT +EQVTANLGRMNLRDIRVDRLEQQLQPRYLTDPRDTATPEGMIDLLVKLQSRQLLSENSTA +LLLKIMTDSPTGQKRLKAGLPPGWSIAHKTGTGEDVATNDVGLISSPTGKHIAIAVFIAG +SKAPLEQRESVMSAVASAVVQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Agromyces sp. Root81 TaxID=1736601 RepID=A0A0Q8W255_9MICO +hrRLTEAIAELERATSVTIGVTALWHDSRRAF-RYRGDERFPMCSLFKSFAAGALVQARG +YDEEYWTTPIPFTDADVVGKETKLNRD-TWQATPEELADAAIRYSDNTAGNLLLRELGGP +QAVTTFARSLGATRTRLDRPEPQVNEATPGDERDTSTPDDIAFLLQLLLIDQGAGALTTA +RLQEWMLRNTTSGKRILAGLTPPFELADKTGLGGYGVVNDAGVIWRPGEEALTLAILTRT +DRTDAPSNHDVLADVTRLIVA-- +>[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium UBA8543 TaxID=2055766 RepID=A0A3C0NHT1_9CYAN +----------------------VLDLDTGERW-FRNGKQRFPMQSVFKLPVGIVVLKLVD +EGKLSLNQSVTITREQFVPWSPILKEIKGDRFTVQYLLQRAVGDSDNTAADALVRLVGGP +EQVTAILGRMNLRDVRVDRLEQQLQPKYLTDPRDTATPEATVNLLAKLQARQLLSEDSTA +LLLKIMTDSPTGQKRLKAGLPPGWTIAHKTGTGPGAATNDVGIISSPTGKQVAISVFIAG +SKAPMEMREKLMAEIASTVVKEf +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter estronivorus TaxID=1172626 RepID=UPI0012E892AA +---FEAQIARLANGAQGRIGVAAVDLSDGHEV-AILGDQRFPMASTSKIAIAATFLDGVD +NGRWSLTSEYPLLIPVRSQFSSATAPVRKGALPAHDLIERMITRSDNNATDALLAVIGGP +EAVNRWVRKAGIKDFRIDRDIATLVRASHIDPRDSATPHAMVQLLSGLYKGRWLSQASRD +VLIGAMERCITGKRRIRALLPEDVQVAHKTGSLNN-TSSDIGIIKTSDGRAYAVAIYVTG +QG-TRLAREHRIAEIAKAIYDGy +>[subseq from] Beta-lactamase n=1 Tax=Sediminispirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228) TaxID=573413 RepID=E1R6Z1_SEDSS +-nNLRQDIEQFLVEKKALVGVSVLGIEDNESL-SINNDKHFSMQSVYKFHIALSALHEVD +TGNLSLEDSIMLKESDLLPWSPLRETYLAGKITLAELINYTVALSDNNGSDILLRLIGGT +EKVNEYIHGLGIIDVQITTDEENMHKESDLQFENWTTPEAATELLTLFYDGKVLSKQSTD +FLWKVMAGTETGGGRIKGKLPSGTLVAHKTGTSATVAINDIGIVTLPNNNHFVMSVFVAN +SKESYETNEKIIADITKLVWNYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flagellimonas algicola TaxID=2583815 RepID=UPI00110D672C +-eTLRHQIEGIISSKNATVGVAINGMDAKDTL-SINGQRHFPMQSVFKFPIALTILAEVD +KGNLSLDQKIDIKKSQLLPWSPLRKKYPEGGIPLDEIIEYTVALSDNVGCDALLRLLGEP +RAVERYFSKLGFTDFAVKINEEVMQGNWELQFLNWTTPKEANRILATFYENNLLSKKSYD +FIWDIMKGTKTGKKRLRGHLPEETIVAHKTGWSGTAAVNNIGIVFLPSGEHFTISVFVTE +SSESLETNEKIIAEISKAAWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000E6A573B +-----SELKHIEQENDVTIGVYGMNTDNGKVY-KHNPDERFAFASTYKAIASGILLNNVP +--NGKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIIQEIGDI +EGFNNELKGLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLVSNQMDKDNQA +LLKQVMIENETGDSLIKAGVSKQYIVGDKSGQGTYGTRNDLAFIYTDHRKPIILAVYTKQ +DQKNAKPDDKIIAAAAEEAIK-- +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium angstadtii TaxID=558151 RepID=A0A0J7IFR8_9FLAO +-eNLRTQLQKILSTKNATAGISVKGIEDKDTL-SINGNLNMPMMSVFKFHIALAVLNKVD +QGKWKLDQKFFVKKEELHPWSPMRDEFPDGNLTLDQLLRYTVSHSDNNGCDLLLNRLGGT +ESVQKFINKQGIRDFVIKVDEQQMSS-WENLYVNTTTPLATTELLEKFYKGKVLKKETTR +YLYQIMVETSRGITWMKAGLPKDTEVAHRTGISSRAAMNDVGIVKLPDGKHFILSVYLKN +ITEERAETEKIIADIAKAVWNYy +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudoalteromonas phenolica TaxID=161398 RepID=A0A5R9PYS6_9GAMM +--TLKADIELLLDSKKAKVGGSIWDHNAEPVL-SVNGDSKIPMQSVFKFHIAAAVLSEVD +KGRWSLEDKIKITPNDLDNWSPIRKKYPNGTIPLSEVIRYTVSVSDNVGCDILLSMLGGP +KKLEDYLHQSGIKDIAVKYNEENMQKVWQRQYENWTTANAANTALNQFHMSNLLSAKSHQ +FLWDVMKGSKTGRKTIKAGVPKDTQVAHKTGHSGTGAQNDIGVVFLPNGQHYYISVLVSD +SYETSETNQNIIAKISELTWQFf +>[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=Q5XQD3_AERCA +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSLSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQVAQTAYQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter sp. BO-6 TaxID=2604537 RepID=UPI0013E1AFE3 +--RLAARLRILEAASGGTLGVAFLDTGSGEMI-GHNRAMRFGHASSFKLSLAALVLWRDQ +QGIEEAERQVTWAEDELMSVSPFATERLAQGATLLELAEATQKFSDNAAANILLREIGGP +ERLNEFWRAIGDSQSRLDRIEPQLNHVPAGEVRDTTTPEAMCRTVEALCFGDVLQAAQRA +LLRQWMIDTRTGLRRVRAGIPQDWRAGDKTGTSTGSLYVDIGFVAPADRAPLTFATYFRA +GAAHEPAAEAVLAQVGRVLAD-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. GA093 TaxID=2683249 RepID=UPI00136555D6 +-nELREQLNQIIATKHATVGISIKSIEDKDTL-SINGNLKMPMMSVFKFHIALAVLNKVD +EGKLSLTQKIFIKKEALDPWSPMAEEFPNGNLTLDQLLRYTVSHSDNNGCDILINLIGGT +KVVQKFINKQGIKDFVIKVNEEQMKS-WEKLYINTTTPLATTELLEKFYKGKVLNEATTK +YLYQIMVETSRGLTWMKAGLPENTELAHRTGLSGTNAMNDVGIVKLPNGKHFILSVYLKE +ITETKDDTEKIIADITRATWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma fluviale TaxID=1597977 RepID=UPI000BE2EFEA +-qRLEQELNRIAAIAKAKVGICALHLESGKQV-SLNLQERFPMASTVKIAIAVQLFTLIE +QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT +EAVQNRVRTLGIQGMSVDRTIIQLIARLKTDPRDTSTPDAMVNLLTQIYRGTALKPESRA +LLLGVMERCRGGAARLKGYLPPNTIIAHKTGSLDGSATDDVGIITLPGDGHIAIAVFVGD +SPMPLAEREQTIAHAARSIYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingosinicella microcystinivorans TaxID=335406 RepID=UPI000DBB6BB6 +--RLSDAFKLFAEQTDGTVGVAAQAIGSKEMA-TLNAGTTFPMASTFKIAVAGKIFERID +KGELTLDQMVTVDPKLLVGGMAIQTPHPGIALSVYNLLEFMITQSDNTSTDVLVQLAGGP +AGVTAWLRGQGISGQRVDGDTAHLIYPFNADPRDASTPEAMVQLLLRIHSGKAMSAKSTK +TLIEIMERCRTGEKRLKGLLPSDTVIAHKTGTLNS-VANDVGIITLPNGKQFAIAVFVKG +DTKGKDVQDKVIADIARVAYDHf +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter luteus TaxID=1581420 RepID=A0A0G9MUW2_9SPHN +---LAQRIAQIAEGSRGRIGVAAIDLSNGQSI-SVLGDQRFPMASTSKIAIAATFLEMVD +QGRASLSSEYPMLYPVSSRSSSVAPVRRGEYMSAQNLIEIMITRSSNQATDALLEAVGGP +SAVNAWARRAGLTEFSLDRDIATLVRAHHIDMRDSATPQTMVQLLSGIYQGRWLSPESRR +VILGAMERCRTGTRRIPAMLPSGVSVAHKTGSLNN-TSSDIGILTAPDGRTIAVAIYVTG +QG-SRPNREARIASIARAIYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Croceicoccus mobilis TaxID=1703339 RepID=UPI0009ED5BA8 +--QALAALRALDTQAGGTLGAFILDIANGENI-VWQSSRRFCHCSSFKLSLAALMWREVD +AGRLDPEEMLPYTRDDLMAVSPVTTRNLDESLPIRTLARAIQVTSDNAAANLLLRRLGGP +KGLTAFWRSIGDDVSRLDAYEPELNRIPPGTTENSTTPEAMARTVARLTTGDVLESDSRE +TLRQWMADTVTGTRRLRAGVPDEWWVGDKTGTSLPSTYVDIGLMIPAGGTPLAVAAYYVT +PEEMNPESEAVLAQVGRIAAD-- +>[subseq from] Beta-lactamase n=1 Tax=Runella sp. HYN0085 TaxID=2259595 RepID=A0A344TDU6_9BACT +-dALRSNIQQIVSSKNAIVGVSIIGNNGKDTM-SLHGDRRFPMQSVFKFHIALAVLSEID +KGKLSLDQKIKIGKDELLPWSPLRDENPNGGFTIERLIQYSVSNSDNTACDVLIRLIGTP +KTVEEYFKKNNIQDIQITYNEEEMQSKWENMFENWTTPKAASETLKMFYENNLLSKSSYD +FFWKTNIETTTGEKRIRGLLPKGTIVAHKTGWSGTAAVNNIGIVFLPNGEYFIISVFVSE +SKENFDTNEKIIADIAKATYDFy +>[subseq from] Beta-lactamase n=1 Tax=Allofrancisella guangzhouensis TaxID=594679 RepID=A0A0A8E6P4_9GAMM +--ETSEQIKKLEIKYGGKIGIYLIDYNNKSHF-GYNQNFYFPICSVYKFLVVGAILKESM +ITPNFLNEKIKINKNDIIGYTPITSENIDKKLTIEELSKAAI-LSDNTAANLLIKKLGGL +KNLNKFIWSLDDKDTKITVNEPTINNVDLRDSLNKTTPQIIAKDLNKIAFKKVLNKKYQL +IFKKWLQENDTGKNRIAFSIPKEWKVGDKTGTCEYGTTNDVAIIWPKNKKPIIISVLYTQ +VNKNAKANDIVIQKITKILLD-- +>[subseq from] PER family class A extended-spectrum beta-lactamase n=1 Tax=Rheinheimera sp. KL1 TaxID=1635005 RepID=UPI0006A95051 +---LKEQIESIVIEKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELIGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSASSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGYSGTAATNDIGIILLPDGRSLLVAVFVKD +SAESTRTNEAIIAQVAQAAYQ-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. JCM 19047 TaxID=1460641 RepID=W7ZPJ7_9BACI +----AATFSVLEDHYDARLGVYALDTGNGQTI-AYNEDERFAYASTHKALAVGVLLQQLS +--LDELDTQILFSEADLVTYSPITEQHVETGMSLHEISDARFATATIQRLILFSMKLAVH +QGLKRHSEKLEDEVTEPERIETELNDVKPGETRDTSTAKALAESLYAFSLGDALDEEKQT +LLNDWLIHNTTGDALIRSGVPEGWLVGDKTGSASYGTRNDIGIIWPPDEDPIVIAVLSSK +EQADAESDDALIAEATEAAL--- +>[subseq from] Beta-lactamase n=2 Tax=Staphylococcaceae TaxID=90964 RepID=Q49V79_STAS1 +--TFAKDIEQIENEYNTKVGIYGINTENGKAY-QHNADERFTFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNESNLS +LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000AC01B91 +--TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLSSILTSNEMNESNLS +LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. OV705 TaxID=1500289 RepID=UPI000648FA97 +-eRLRKEIQQIIASKNATVGISIKNIEDKDTL-SINGNSMMPMMSVFKFHIALAVLDQVD +KGKLKLNQKFFIKKEDLLPWSPIQEEFPNGNLTLDQLLKYTVSHSDNNGCDILLRILGGT +EPVQKFINQQGIKDFIIQVNEQQMS-NWDNLYLNVTTPIATTALLEKFYNGKVLKENTSQ +YLYQIMTETSRGLTWMKAGLPDHTELAHRTGISSRAAMNDVGIFKLPNGKHIILSVYLKN +ITEERTDTEKLIADIARATYNYy +>[subseq from] Beta-lactamase n=1 Tax=Spirosoma pollinicola TaxID=2057025 RepID=A0A2K8YX01_9BACT +--DLQKQIATIAKSIPGRVGVAASVVETGEVV-QWQGNAEFPMQSVYKLPIAMAVLNQVD +EGRLKFDQRVNVEKVNYIAHSPIRDEYQDGTISISELLRYAVSESDGSASDIVMAQAGGP +AVVMSYLNSIGVRDIKVADTERTLGLDATSQYRNWAKPVEAVKLLGLLQQGVGLSASSRS +YLLRLMTETETGLNRLKGQLPQGVKVAHKTGTSQTAATNDIGLITVDEHKHIALAVFIKD +SAASTKEREAVIAQVAKLVYDRw +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. 17S1E7 TaxID=2497456 RepID=UPI000F86BECC +---LEPKINSILKNKKATVAVSVLGFENGFRY-DKNGDKKLPMQSVFKFHIAAAVLNAVD +QGKLSLDQKIKLDQSNLLEWSPLRDQYAGKEIPLSEVIEYTVAKSDNNGCDILLRLLGGT +QPVQKFMDTKGIKDFQIKYNEEDMHKDWNVQYQNYSTTRSAANALKKFYDGKLLSKKSTD +YLMKVMLSTSTGLNKMVEQLPKNTPVARKTGSSGTGAENEIGIVTLPNGRHYALAVFVSN +STETDAVNCKMISDISREVWEYf +>[subseq from] Beta-lactamase n=1 Tax=Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896) TaxID=504472 RepID=D2QNF5_SPILD +-qRLEQELNRIAAIAKAKVGICALHLESGKQV-SLNLQERFPMASTVKVAIAVQLFTLIE +QGKLSLMTMVDLQPSDLHPGSGTLEVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT +EAVQNRLKTLGIQGMSVDRTIIQLIARLKTDPRDTSTPDAMVNLLAQIYRGTALKPESRA +LLLGVMERCRGGAARLKGYLPPNTIIAHKTGSLDGSATDDVGIITLPGDGHIAIAVFVGD +SPMPLAEREQTIAHAARSIYDFf +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Chryseobacterium lathyri TaxID=395933 RepID=A0A511Y8N8_9FLAO +---LEQKINSIIKDKKATVGVSVLGFENNFKY-SKNEDMPFPTLSVFKFHIACAVLDLVD +KGKLSLGQKIFISKSDLMEWSPFREKHPDGNVSLNEIIDYTVALSDNNLCDVLLKLIGGT +KTVQGFMDSKGVKGFQIKYNENEMHKDWKALYENYSTTNSAVQLLKKFHDGKLLSKKSTD +YLMQIMIGTKTGTNKIVEQLPKNTPVAHKTGASGKNAENDMGIITLPNGKHYAIAIFVSN +SMESNAVNCRLVSDISKAVWDDf +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium limigenitum TaxID=1612149 RepID=A0A1K2ITQ5_9FLAO +---LEKKINSIIKDKKATVAVSVLGFENGFKY-NKNGEKKLPMQSVFKFHIAAAVLDLVD +KGKLSLDKKILLDKSNLLEWSPLRDKYKDKNVPLSEIIDQTVAMSDNNGCDILLKLIGGT +QTVQKFMDSKGVKGFQIKFNEEEMHKDWQAQYENYSTTNSAVQVLKKFYDGKLLSKKSTD +YLMKVMLGTKTGLNKMVEQLPKNTPVARKTGSSGTGAENEIGIVTLPNGKHYAIALFVSN +STETDAVNCKIISDISKSVWDHf +>[subseq from] Beta-lactamase n=1 Tax=Thioclava arenosa TaxID=1795308 RepID=A0A2A4CN74_9RHOB +--SVGAAIERVATKLAGRIGFAAQEIGGDDVI-AFNGDEAFVMASTYKVAIAAAVLDRVD +KGELSLDQMVEVTLDMMMIGDAALNTHPGLQLSIANVIEVMITESDNTATDISMGLAGGP +AAVTQYLRRIGISDIRVDRPTGEIIGDFEADPRDQATPLAMLQLLLAIDSGAATSAESRD +FLIDVMSRTRTGAGRLKGLLPRGTPVANKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS +SETSEADRDRAIAEVARSLFDYf +>[subseq from] Beta-lactamase n=1 Tax=bacterium BRH_c32 TaxID=1734400 RepID=A0A101VYC7_9BACT +--SLRERITQIIEGKDAIVGIAVEGYDGKDTL-SINGSKRFPMQSVFKFHIALAVLNEVD +KGELNLNQKITITKEDLIPYSPIRDKYPNGTMKLSEILTYTVGESDNVGCDILLKLIGGP +QVVEKYLHSKNIDDVAIIYNEKDQQSNWENQFQNWTTPHSANQTLIKYYENNLLSKRSYD +FLWKTMEGSKTGKKSIRGELPKNSVVAHKTGHSGTAAVNDIRIVFLPNGKYFYLTVFVSN +SKEDEEINQKIIAEVSRASWDYf +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. JV274 TaxID=1932669 RepID=UPI00098492EF +---LEQKIHSILKNKKATVGVAVLGFENGFTY-DKNADKNLPMQSVFKFHIAAAVLNAVD +QRKLSLDQKIVLNKSNLLEWSPLRDKYPGGNVPLSEVIEYTVAKSDNNGCDILLKLLGGT +QPVQKFMDSKGVKGFQIKYNEEGMHKDWKAQYENYSTTKSAVHVLKKFYDGKLLSKKSTD +YLMQVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGTHYALAVFVSN +SMETDAVNCRMISDISKEVWEYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q5MDG3_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGDW------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma fluviale TaxID=1597977 RepID=A0A286GX03_9BACT +-qRLEQELNRIAAIAKAKVGICALHLESGKQV-SLNLQERFPMASTVKIAIAVQLFTLIE +QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT +EAVQNRVRTLGIQGMSVDRTIIQLIARLKTDPRDTSTPDAMVNLLTQIYRGTALKPESRA +LLLGVMERCRGGAARLKGYLPPNTIIAHKTGSLDGSATDDVGIITLPGDGHIAIAVFVGD +SPMPLAEREQTIAHAARSIYDYf +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium tardaugens NBRC 16725 TaxID=1219035 RepID=U2ZQ63_9SPHN +---LEAQVARYADGSKGRIGVAAVDLSSGREI-AILGDQRFPMASTSKVAIAATFLDGVD +KGKWSLSSEFPLLVAVASPSSAIAPVRKSTYMSASQLIDLMITRSSNPATDALLAAIGGP +AAVNRWMRNAGINDFRIDRDIATLVRASHIDQRDSATPRAMVQLLSGLHQGRWLSASSRR +VIMSAMERCVTGKRRIPALLPVGVQVAHKTGSLNN-TSSDIGIISGPDGRTYAVAIYVTG +QG-TRLAREERIAQIARAIYDGy +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. 7 TaxID=2035214 RepID=A0A497UQ61_9FLAO +-sQLEQKVSSILKNKKATVGVSVLGFENGFKY-DKNADKKLPMQSVFKFHIAAAVLNSVD +KGRLSLDQKIKLNKSNLLEWSPLRDQYAGKDIPLSEVIEYTVAKSDNNGCDILLKLLGGT +QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYQNYSTTNSAVDVLKKFYDGKLLSKKSTD +YLMKVMWSTSTGLNKMVEQLPKNTPVARKTGSSGTGAENEIGIITLPNGKHYALAVFVSN +SMETDAVNCKMISDISREVWEYf +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii Naval-57 TaxID=903927 RepID=A0A656I7Y0_ACIBA +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSDSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQVAQTAYQ-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X9B1_9BACT +--------QEIASVTKGPVGAAAMIVETGEKA-SISGSEHFPMQSVYKLPIAMAVLKRID +NNTLTFDDKIAVKPKDFVSEFSIAIKYPKGALSIRELLDYMISESDGTACDALMRMLGGP +EAVTKNLREWGVNDIVLATYEQDMFKTPAVSFQNWSTPDAMVQLLRLLQTEKVLSAERRD +ILLSLMIKSRPGQQRIKGLLPPGTTVAHKTGTSGTTATNDVGIVTLPNGRHLAIAVFVSS +TTADQETREGVIAKIARAASDCw +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Syntrophaceae bacterium PtaB.Bin095 TaxID=1811717 RepID=A0A1V4XDD3_9DELT +--RLISEIGRLARLSGGVVGVSAVHIESQKRI-SFNGRERFPMASTYKIPIAVQLITLVE +RGELAWDRMVEIRETDLRPGSGVLAKLFDKPVSLRNLFEIMMVVSDNTATDLLLSIAGGP +GAVTRQMRAVGIVDIDVSRSVFEMIAEFEADGRDTATPDAVVSLLQGIYRGDFLRPESAG +MLLDAMRRSQTGEARLKGMLPPGTPVAHKSGTLG-GSTNDAGIISLPDGGHVAIAIFVKT +SRKEATEREKAIAEIARAVYDFy +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Citrobacter freundii complex TaxID=1344959 RepID=A0A3Q8H2Z2_9ENTR +------------------------------------------------------------ +-----LQQQVVIKPSDLVNYNPIAEKHVNSTMTLAELSAAALQYSDNTAMNKLIAHVGGP +QKVTAFAREVGDSTFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGETQRA +QLVTWLKGNTTGNASIKAGLPATWVVGDKTGSGDYGTTNDIAVIWPENHAPLIL------ +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=B2CD46_ECOLX +-------------------------------------EERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVQDH---------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T3L9_9BACT +-dKLKTEIDSLVKSKNATVGVSIIANNFKDTI-NINENLHYPMQSVFKFPIALAVLSEVD +KGNLKLNQEIIIFPKDLLPWSPIREKFPDGTMTVADIIKYTMAQSDNNGCDILLRLLGGT +TAVEEFLSQHQITDISIKFNEEDMHKEWNIQFQNWATPIALTKLLAKFYVDNILSKESYE +FLWRVMSETTTGTDRLKGQLPQDIIIAHKTGTSGTAAINDIGIIILPNGNPIFISVLVSN +STEDHGANEKIISDIAKKVWDYy +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C7ACC3A +------------------------------------------------------------ +----------------LVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLASQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. Leaf394 TaxID=1736361 RepID=A0A0T0M9C1_9FLAO +---LDKKINSIIKGKKATVGISVLGFENGFKY-SKNAEKKLPMQSVFKFHIAAAILDYVD +KGKLSLDQKVLLTKDNLMQWSPLRDKYPNGGVPLSEILELTVAQSDNSGCDILLGLLGGP +KTVQQFFDAKNVKNFQIISGEAEMHKDWNVQYKNYSTANAATDALKKFYDGKLLSEKSTD +YLMKVMLSTSTGKNKLIEQLPKNTPVARKTGASGTGAENEIAVVTLPNGRHYAIAVFVSN +STESSDVNCKMISDISKVVWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma agri TaxID=1987381 RepID=UPI0013DCB0D5 +-qRLEHELERIAKLAKGNVGVCALHLESGKQV-SMNLQERFPMASTVKVAIAVQLFTLIE +KGDLSMMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGP +TAVQNRLKTLGITGMSVDRTIIQLLAKLKTDPRDTSTPAAMVNLLTQIYRGRALKPENRA +LLLGVMERCRGGAARLKGYLPPNTIVAHKTGSLGGSATDDIGIITLPGDGHIAIAVFVGD +SPMPLTEREQVIAHTARSIYDYf +>[subseq from] class A beta-lactamase n=2 Tax=Citromicrobium TaxID=72173 RepID=UPI0009E7D91A +-eQLAAQIDRLEAASGGRLGLALFSQDEGLVF-AHRGAERFAMCSTFKLALAAMALETPG +----VREERLDFGADDILSYAPYAKGRAQIGMSGLEAAHHAVTLSDNTAANLLLVRLGGP +EAFTAWLRDAGDRVTRLDRNEPTLNENAPGDPRDTTTPGAKAELVGNLLWGDRLSATDRG +ILHGWLVETSTGMARLRGGLPDGWNAGDKTGTCGQPEFNDIAVFETPSGSRYVLAAFLDR +PKGTSAEADAVLADAARVVAE-- +>[subseq from] Beta-lactamase class A n=2 Tax=Plantibacter sp. YR521 TaxID=2135468 RepID=A0A495AY68_9MICO +--EIAAKIGRIEGEFAVTVGAVAIG-ESGQVV-EYNGEARMPYASTMKVFVAAALLASTP +VDERETIVRWTQAQLDVAGYSPLTSEHLDDGLTLDALAEAAVRDSDNTAANLVMESLDGP +SGVQDFLRALGDPTTVVTEYEPELNAVVPGSDQNTSTPLALATDLKTIFEGDALEQGSRE +TLLDWMTGNATGDALIRAAAPSGWTVADKSGGAG-GVRNDVAVVTTESGEQIYIAILTAT +KDPAAAYTDEVVERVARDLLAEf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B2CD68_KLEOX +-------------------------------------EERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVQDH---------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingosinicella microcystinivorans TaxID=335406 RepID=A0A495RKN2_SPHMI +--RLSDAFKLFAEQTDGTVGVAAQAIGSKEMA-TLNAGTTFPMASTFKIAVAGKIFERID +KGELTLDQMVTVDPKLLVGGMAIQTPHPGIALSVYNLLEFMITQSDNTSTDVLVQLAGGP +AGVTAWLRGQGISGQRVDGDTAHLIYPFNADPRDASTPEAMVQLLLRIHSGKAMSAKSTK +TLIEIMERCRTGEKRLKGLLPSDTVIAHKTGTLNS-VANDVGIITLPNGKQFAIAVFVKG +DTKGKDVQDKVIADIARVAYDHf +>[subseq from] Beta-lactamase n=1 Tax=Aquimarina sp. MAR_2010_214 TaxID=1250026 RepID=A0A2N3T2Y7_9FLAO +---LRKKIEQIVSEKNAVVGVSIIGNNGKDTL-SLYGDKRFPMQSVFKFHIALAVLSEVD +KGILSLDQIIEIDKDELLPWSPLRDENPNGGFTIKKLIQYTVSHSDNTACDVLIRLIGTP +KTVEEYIKKSGIEDIQITFNEEEMQAKWENMFQNWTTPNAASETLKIFFENNLLSKSSYD +FFWKTNKETTTGKGRIRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPDGKYFIISVFVTD +SQENFKTNEKIIADIAKATYDFy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacter sp. SA-A5-114 TaxID=502288 RepID=B2CD65_9ENTR +-------------------------------------EERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVQDH---------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013307FC4 +-----------------------------------------PMMSTFKVLLCGAILVRVD +KGLEQLERRITYNKHDLDDYSPLTSQHIADGMTVSELCNAAITTSDNTAANLLLSTIGGP +AGLTHFLRSTGDSYTRLDRHEPSLNGAKPGDERDTTTPAAMAQTLQKLLNESVLTEKSRK +KLISWMQEDKVGGPLFRSVLPAGWMIADKTGAGDHGSR---------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Aeromonas sp. GK7 TaxID=1009023 RepID=K4EJN1_9GAMM +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSLSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQAAQTAYQ-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Runella limosa TaxID=370978 RepID=UPI00041BCABA +--DLKKKISQIVAGKKAKVGVAILGPTPTDTL-SFYGNERFPMQSVFKLHIGLAMLSEVD +KGKFKLNQPINVGKEDLIPYSPLRDAHPNGGIELSKIIEYTVAESDNVGCELLLKLLGGP +KFVEQYLLQRGFKNVSIKINEQVMQKNWELQYQNWTTPKAANELLTAYYFKKLLSAKSHE +FLWKVMKGTKTGKNRLRAQLPPETVLAHKTGSSGTAAVNDIGVLILPSGSPVFISIFVTN +STENEATNEKIIADIGKATWDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium takakiae TaxID=1302685 RepID=A0A1M4W5Q9_9FLAO +-sALEQKINSIIKDKNATVGISVLGFENGFKY-NKNADKKLPMQSVFKFHIAAAVLDYVD +KGKLSLDQKILLDKTNLHEWSPLRDKYPQGNVPLSEILEYTVAKSDNNGCDILLTLIGGT +QTVQKFMNSKGVKGFQIKFNEEEMHKDWNAQYENYSTAVSATDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGKNKLIEQLPENTPAARKTGASGTGAENEIAIITLPNGKHYALAVFVSN +STETDVVNCKMISDISKSVWDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium chaponense TaxID=713588 RepID=A0A1N7M618_9FLAO +-qDLKKEINAITNDKNATVAVSVTGIDFPLHFeNKNGEKKLPMLSVFKFHIALAVLNKVD +QGKLKLDQPIFIKKADLLEWSPIREKYPDGNMPLSELIKYTVAKSDNNGCDLLLRLIGGT +ETVQKFINNKGIKNFTIKADEAQMHKGYEFMYWNTTSTNDSNLLLMNFFDGKVLSKNSTS +FLMKTMIETTTGTTKIVAQLPKGTPVAHKTGSSGKDAENDIGIITLPNGKHYAISVFVSD +SMETEETNTKIIADISKRVFDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Hymenobacter terrenus TaxID=1629124 RepID=UPI000619AACA +-eSLEQRINRLLVAKKATIGISIYCFETKEAV-SINGNEHFPMLSVFKLHIAMAVLNEID +KGRFSLNQRIHVKPEDLLPFSPLRDEYPNGNIPLAKIIEYTVGKSDNSGCEILLELIGGT +QMVNKYFRKAGMKDICIQVNEEEMHKNWNDQFLNWTTPVSAVEVLKLIYSRKLLSKTSSD +FLWNSMAATSTAGKRIKGNIPVDAVVAHKTGTGRTAAVNDIGIVASPNGRHFAVSVFVAN +SLENIETNEKVIADITRLAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A140CWH6_ECOLX +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHYPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWDYy +>[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. HMWF022 TaxID=2056858 RepID=A0A2R7PPR9_9GAMM +----ASDFAALEKACSGRLGVTLLDTGSGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDPALLDRRLPVRAQDILEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRATGDTITRSDRLEPELNSFALDDPRDTTTPAAIAATLRRLVLGDALKPA--- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Roseateles depolymerans TaxID=76731 RepID=A0A2W5DWC3_9BURK +--DLPAALQALESRAGGRLGFAVLDTGSGRLQ-GLRLDERFGMCSTFKLPLAALTLRAVE +QGELQ-DDWVALGEITPRDFAPATRAQLPAGMKLLALAEAAQTTSDNIAANLLLQRLGGP +AGFTQRLRALGDTVTRLDRIEPSMNLVLPGDERDTTSPAAMAHTVAAILTGSWLRPEGVA +TLRRWTEATRTGARRLRAGLPADWPAGDKTGTGLPDRTNDVAIVWPAGRAPWVMAAYYEG +RGQMPAADEAVLAEAARLAV--- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium oncorhynchi TaxID=741074 RepID=A0A316X0U9_9FLAO +-qDLRNKINTITSTKNATVGISVKGIEDKDTL-SINGNKETPLMSVFKFHIALAVLNRVD +KGKLKLNQKFFIKKEDLIPWSPIREEYPEGNLTLDQLLRYTVSHSDNNGCDILLNIIGGT +DSVQKFINQQGIKDFTIKVNEQQMSS-FDKFYLNTTTPLATTALLEKFYNGKVLRKETTK +YLYQIMVETSRGLTWMKAGLPAGTELAHRTGISSRAAMNDVGIVKLPNGKHFILSIYLKN +INEEMAVTEKIIADISNAVWEYy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Providencia rettgeri TaxID=587 RepID=C0KTK2_PRORE +---LKGQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQVAQTAYQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI0010117D0F +--TFAKDINQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS +LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Syntrophus sp. PtaB.Bin138 TaxID=1811711 RepID=A0A1V4XP62_9DELT +--RLEQEVKRLAALAGGTVGVSALHIESGRSF-SFNGGERFPMASVYKIPIAVQLLRRVD +RGEVRLNSTVTLRSGDIHPGSGRLIKTFKKKYSVRELLELMLLISDNTASDAILKLAGGP +AAVTAAMKSLGIQEMDVSRPTLNMLARFHTDRRDTASPDAMTSLLAMVYDGTALQPETTS +VLLGIMERCQTGNSRIKDLIPPGMKVANKTGTIGPSMVNDAAILTLPGEGHVALAIFIKT +SNRSITQQEQAMAQIARYLYDYy +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Syntrophus sp. PtaU1.Bin005 TaxID=1811712 RepID=A0A1V5DL53_9DELT +--RLEQEVKRLAALAGGTVGVSALHIESGRSF-SFNGGERFPMASVYKIPIAVQLLRRVD +RGEVRLNSTVTLRSGDIHPGSGRLIKTFKKKYSVRELLELMLLISDNTASDAILKLAGGP +AAVTAAMKSLGIQEMDVSRPTLNMLARFHTDRRDTASPDAMTSLLAMVYDGTALQPETTS +VLLGIMERCQTGNSRIKDLIPPGMKVANKTGTIGPSMVNDAAILTLPGEGHVALAIFIKT +SNRSITQQEQAMAQIARYLYDYy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium circumlabens TaxID=2133765 RepID=A0A4Y7U8M7_9FLAO +-nELRQQLQQLIAGKNATVGISIKSIEDKDTL-SINGNLKAPLMSVFKFHIALAVLNKVD +EGKLSLTQEIFIKKKDLHEWSPMREEYPNGDLTLDKLLRYTISHSDNNGCDILIDLVGGT +KEVQRFINKQGIKDFVIKVNEEQMKT-WKNLYINTTTPLATTELLEKFFKGEILKENTTK +YLYQIMTETSRGITWMKAGLPENTELAHRTGMSGTNAMNDIGIVKLPNGKHFILAVYLKN +ITETQEDTEKIIADITRATWGYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Pedobacter suwonensis TaxID=332999 RepID=UPI0011A838D4 +---LNDKIQQIIASKHAKVGIAIKGPNERDAL-SINGNEHFPLQSVFKFHIALAVLSQVD +KGKFSLGQKIKISKKDLLPYSPIRDRYPDGVLPLSEILAYTVSQSDNVGCDILMRMIGGP +EFVEKYCNSIGIHDVSIKINEEEQQGNWNSQFKNWTTPKAANNILELFYMNNLLSKKSHH +FIWKVMRKTKTGAHRLRGLLPKNTLIAHKTGSSGTAAVNDIGIVFLPNGSYYFISVFVTE +STENEVTNEKIIADINKEAWEYf +>[subseq from] Beta-lactamase n=1 Tax=Tenacibaculum sp. SG-28 TaxID=754426 RepID=A0A2S7TLW9_9FLAO +---IRSKIDSLLALKKATVGIAISGVGKGDTL-SYNGHKHFPMQSVFKFPVALAVLHEVQ +CGRLSLAQKVHINKDDLLPWSPLQKKYPKGVLSLAEILQYTVAWSDNVGCDVLLKLLGGP +LTVEKYFHRLGFTDIAVKINEETMQSNWDLQFLNWTTPKEANTILKQFFTNGLLSAPNYT +FIWDLMKATKTGKNRLKGKLPTGTIVAHKTGSSGKHAVNDIGIVFLPNGNYYLLSVFVAN +SKESFKTNEKIIADISKVVWNYf +>[subseq from] Putative beta-lactamase n=1 Tax=Scytonema sp. HK-05 TaxID=1137095 RepID=A0A1Z4J5Y6_9CYAN +----QERLKNLDSAAQGKVGIGVLDLNSGQSW-FLNGKQRFPMQSVYKLPSGIAVLKQVD +EGKISLKQLVTIMRQDFAPSSPMIKEFKGDRIPLRNVLESSVGISDNTAADALVRLLGGT +KQVNAILSKLQIRNIRVDRLEQQMQPKYLTDPRDTATPEAMVDLLAKLNSNQLLSENSTA +LLLKIMTDSPTGQKRLKAGLPENWSIAHKTGTGAGTATNDVGIVSSPDGKRVAIAVFIAG +SKAPLEEREKVMSNIASRVVQ-- +>[subseq from] Serine hydrolase n=1 Tax=Larkinella knui TaxID=2025310 RepID=A0A3P1CNP2_9BACT +-qRLNQELERIVKLAKGKVGICALHLESGQQI-SLNLKERFPMASTIKVAIAVELLTKIE +KGELSLMTIVDLQPSDLHPGSGTLDVLFNKPLSVQNLLELMMVISDNSATDILLRLVGGV +EPVRERLKILGIQGMSIDRSIIQLLAKLETDPRDTSTPEAMVNLLTQIYRGKALKPASRD +LLLAVMERCRGGLNRLKGYLPPATVVAHKTGSLDGSATDDVGIITLPGDGHIAIAVFVGE +SPQPLEQREQTIAHVTRTIYDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina sp. Aq349 TaxID=1192023 RepID=UPI000D55CCF1 +---LRKKIEQIVSDKNAVVGVSIIGNDGKDTL-SLDGDKRFPMQSVFKFHIALAVLSEVD +KGTLSLDQIVEIDKDELLPWSPLRDENPNGGFTIERLIQYTVSHSDNTACDILIRLIGTP +KTVEQYIKKSGIEDIQITFNEEGLQAKWENMFQNWTTPNAASETLKIFFENNLLSKSSYD +FFWKTNKETTTGKGRIRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPDGKYFIISVFVTD +SQENFKTNQKIIADIAKATYDFy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL47_ECOLX +-----------------------------------------------KVMAAAAVLKKSE +XEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDI------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium oncorhynchi TaxID=741074 RepID=A0A316X579_9FLAO +-sELEQKISSIIKGKKATVGVSVLGFESNFKY-NKNGDQKLPLMSVFKFHIACAALDLVD +KGKLSLEQKIFIKKADLHEWSPFREKYPNGNITLHEIIDYTVALSDNNLCDVLIKLVGGT +KAVQQFMDSKGVKNFQIKYTEHDMANDWKALYENYSTTNSAVQMLKTFYDGKLLSKKSTN +YLMQIMLGTKTGTNKIIEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVVN +STEAEAINCRIVSDISRAVWDNf +>[subseq from] Beta-lactamase class A n=1 Tax=Soonwooa buanensis TaxID=619805 RepID=A0A1T5GB87_9FLAO +-kDLRTSIQEIVKNKKANIGVAVWHLEKQDTL-SVNGHRHVPMQSVFKLPIGLAILDLVD +KGKFKIDQKIKFTKEELLPHSPLRDANPNGGLTLLEMIKYTVANSDNNGCDILLDRIGGV +DVVQKYMNRIGIKDFQIATNEQEMHVVTELQYQNYWNANSANDLLEKLYTKPILKEASKK +EMIKILEETNTGVKRLKGELPQGTLVAHKTGTSYTAATNDVGVITLPNKEHVIVSVFVSD +SYEKEATNEKIIADIAKASFDYy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=T1YZQ0_ECOLX +------------------------------------------------------------ +------NQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVLGDKTGSGGYGTTNDIAVIWPKDRAPLILV----- +----------------------- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. ACN2 TaxID=1975676 RepID=UPI000BB3DE13 +-nELRNQLQQIISSKNATVGVSIKNIEDKDTL-SINGNLKMPMMSVFKFHIALAVLHKVD +EGEFNLTQEIFVKKKDLKEWSPMKEDYPEGNLTLDKILRYTVSHSDNNGCDILIKLVGGT +KYIQKFINEQGIKDFVIKVNEDQMKT-WKNLYINTTTPLATTELLEKFFKGKVLKEETTK +YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISGTNAMNDIGIVKLPNGKHLIVSVYLKD +ITEKKEDTEKIVADITKAVWNYf +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma aerolatum TaxID=1211326 RepID=UPI0009ABE17A +--QFRTKIEQIAQDAQGRVGVAATLLETGESV-GFHENEQYPMQSVYKLPIGMAVLHQVD +QGKLVLAQLVHVSKSDYISHSPIRDKFPQGAITLAELLRYAVSESDGSASDVLLRVLGGA +EVVMNYLRTLGITGVMVLNTEREIGSDNAVQYRNWAKPSQLVALLKAVQAGKGLSRTSHA +LLLHLLTDTQTGRQRLKGLLPAGSLVAHKTGTSWTAATNDVGNLTLPDGRHIAIAVLVSD +AKADATTREAVIARIAKAAWDYw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0H3WJJ7_KLEPN +-------------------------------------EETFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLR------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WR07_9BACT +--------QEIASVTKGPVGAAAMIVETGEPV-SINGGDHFPMQSVYKLPIAMAVLSRID +NKTLTFDQKVRVDPKDFVSEFSIATKYPNGAISIRELLDYMISESDGTACDALMRMLGGP +EVVTKYLRDLGVQDVVLATYEQDMFKTPSVSFQNWSTPEAMIQILKLLQVGKVLSEERRD +ILLSLMIKSRPGPQRIKGLLPAGTTVAHKTGTSATTATNDVGLITLPSGQHLAIAVFVSN +TTADQKTREAVIAKIARAATDCw +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=A0A411DMH2_9FLAO +---LEQKINSILKNKKATVGVSVLGFENGFRY-NKNADKKLPMQSVFKFHIATAVLNAVD +QGKLSLDQKIKLDQSNLLEWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLRLLGGT +QTVQKFMDSKGVKGFQIKYNEEDMHKDWNVQYENYSTTKSAVDVLKKFYDGKLLSKKSTD +YLMKVLWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN +STETDAVNCRMISDISREVWEYf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X7H7_9BACT +---LHKRIKELAATVDGQAGVAIMDLSSKDTL-LYNVHGRFAMQSVYKFQLGLAVLNEID +KEALSLDKKIRLTKENLLPYSPMRDKYPGGNLPLRDVLKYLVTNSDNNACDILFKELGGT +KRVNRYVHDLGVNEMEIAATEDEMHQGYDVQFTNWSTPRATLQLLEMFYDKKLLKPASQE +LMWKMMVETTTGPKRLKGLLPEGVEAAHRTGLGDRDAVNDVGIVKLPNGKYYAIVVYIGR +AKGELPDLEKVIAEISLAAYK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter auburnensis TaxID=1457233 RepID=A0A2H9VNJ6_9SPHI +--NIQQQITDIARDAKGIVSFTALNLETRDSV-SYHGEGQMVMQSVMKFPIALAVLHEVE +RGKFSLDQTFKISDRDMHHNGPLFEKYPKGVIPLSELLTYMVSYSDNNACDILLDKIGGV +KPVMDNLRRLRVKGIVVDASELDMSAAWEVQYTNWCKPAAMVQLLDVFYQGKALDKANTD +TLIKKMLQTTTGPKQIKGLLPQGTVVAHKTGRSNTAATNDVGIITLPNGQHLAIAIFIGN +STADLDTRESVIARITKALWD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=B2CD71_ECOLX +-------------------------------------KERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVQD----------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Coxiella burnetii TaxID=777 RepID=UPI001178C2C2 +------------------------------------------------------------ +------------KKNELVSYSPITKNHINGGITVSELCAAALTLSDNSAANLLIKKLGGL +TAINAFARSIGDKQFELDRLEPQLNSAIPGDIRDTTTPEAMANSLKRLTLGDILAFPQXI +QLQTWLKNNTTGNAKIRAGVPKDWIVGDKTGSGGYGTTNDIGIIWPPKRAPIVVAIFFXK +NKKGAVSPDSIIERIXRILM--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=B2CD64_ECOLX +-------------------------------------EERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVQTT---------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium cucumeris TaxID=1813611 RepID=UPI000F44FBF3 +-kDLKNKINQIISTKNATVGISLKGIEDKDTL-SINGNKETPMLSVFKFHIALAVLNRVD +EGILKLDQKFFIKKEDLLPWSPIREEYPQGNLTLDQLLRYTVSHSDNNGCDILLNIIGGT +ETVQKFINQQGIKDFTIKVNEKEMSS-FEKCYLNTTTPLATTELLEKFYKGKVLKKETTK +YLYQVMVETSRGLNWMKAGLPVGTELAHRTGISGRAAMNDVGIIKLPNGKHVILSIYLKN +IKEEMADTEKIISDISHAVWEYy +>[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium detergens TaxID=1145106 RepID=A0A420B7R0_9SPHI +---LRNKIAQIVSDKDAIVGVSIIGNNGQDTI-SLNGDRRFPMQSVFKFHIALAVLSEID +KGNLSLDKKIEIGKDELLPWSPLRDENPNGGFTIEKLIQYTVSHSDNTACDVLIRLIGTP +KTVEDYFKKNNIKEIQITYNEEEMQAKWENMFQNWTTPKAASETIKMFYENNLLSKSSYD +FFWKTNIETTTGANRIKGQLPKETIVAHKTGWSGTAAVNNIGLVFLPNGEHFIISVFVSE +SKENFDANEKIIADIAKATYDFy +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. CF356 TaxID=1500283 RepID=UPI000647B5E4 +---LDQKISSIIKDKKATVGVSVLGFEDGFKY-DKNGNKNLPTLSVFKFHIACAVLNLVD +QGKLSLDQKVVLKESELLPWSPIKEKYPTGDLTLDEIIDYTVALSDNNGCDKLLKMIGGT +QTVQKFMDSKGVKGFQIKVNEDEMHKSWKTQYENYSTTNSAVNLLKSFHNRKILSKKSTD +YLMKIMIGTKTGMNKLVEQLPKNTPVAHKTGASGTVAENDMGIVTLPNGKHYAIAVFVNN +STETDLVNCKMISDISKIVWDYf +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WYE2_9BACT +--RLQERLDNLDSSAQGDVGIGVLDLDTGESW-FRNGKQWFPMQSVFKLPVGIVVLKLVD +EGKLSLNQTVTITREQFVPWSPILKEITGDRFTVQYLLQRAVGDSDNTAADALVRLVGGP +EQVTDILGRMNLRDIRVDRLEQQLQPRYLTDPRDTATPEGMIDLLVKLQSRQLLSEDSTA +LLLKIMTDSPTGQQRLKAGLPPGWSIAHKTGTGENVATNDVGLISSPTGRRVAIAVFIAG +SKAPLEQRESVMSAVASAVVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Enterococcus faecalis TaxID=1351 RepID=UPI00132F8204 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHATRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLA--- +------------------------------------------------------------ +----------------------- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Bacteroidetes bacterium ADurb.Bin397 TaxID=1852812 RepID=A0A1V5P1K5_9BACT +---WKQEIRNIATKYKAVTGVSIYGNSGRDTL-TVNGSAHLPMQSVYKFHIALAVLSEVD +KGKLDLNQKIKITTKDLWPWSPIRDKYPEGTLTLAQILQYTVSESDNNGCDLLLRLLGGP +SFVDNYFRMANFSDISIKATEQEMHSGWDVQFSNWTTPIAATNLLKAFYTNELLSKNSYN +FLLATMKATSTGKQRIKGLLPSGTVVAHKTGTGGTSAVNDIGIVFLPKGNYFLISVMVTE +SGESFETNEKIIADISRIAWDYf +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus saprophyticus subsp. saprophyticus TaxID=147452 RepID=A0A380HNL2_STASA +--TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS +LLKQTMIENKTGDTLIKAGMPNNYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] Serine hydrolase n=1 Tax=Spirosoma sp. 48-14 TaxID=1895854 RepID=A0A1Q3WX97_9BACT +-qRLERELQRISTLAKGKVGICALHLESGKQV-SLNIQERFPMASTVKVAIAVQLFTLIE +QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT +EAVQKRVNALGIQGMSVDRTIIQLLAKLATDPRDTSTPEAMVNLLAQIYRGTALKPDSRA +LLLGVMERCRGGVARLKGYLPPNTVIAHKTGSLNNLATDDVGIITLPDEGHIAIAVFVGD +SPMPLAEREQVIAQSARAIYDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacterium sp. NYYP31 TaxID=2546448 RepID=UPI0012E2DFF7 +---LRNKIEQIVSDKNAIVGVSIIGNNGNDTL-SLHGDRRFPMQSVFKFHIALAVLSEID +KGNLSLDQKIKIDKDELLPWSPLRDENPNGGFTIEKLIQYSVSHSDNTACDVLIRLIGTP +KTVEGYIKKSGILDIQITFNEEDMQAKWENMFQNWTTPKAASETLELFYGSNLLSKNSYD +FFWKTNKETTTGNNRIKGQLPAETIVAHKTGWSGTAAVNNIGIVFLPNGQHFIISVFVSE +SKENFDTNEKIIADIAKVTYDFf +>[subseq from] Beta-lactamase n=1 Tax=Lutimaribacter saemankumensis TaxID=490829 RepID=A0A1G8TJT7_9RHOB +--SVGAAIERVATKLAGRIGFAAQEIGDDEVI-AFNGDETFVMASTYKVAIAAAVLDRVD +KGELSLDQMVDVTLDMMMIGDAALNTHPGLQLSIANVIEVMITESDNTATDISMGLAGGP +AAVTQYLRRIGISDIRVDRPTGEIIGDFEADPRDQATPLAMLQLLLAIDSGAATSAESRD +FLIDVMSRTRTGAGRLKGLMPRGTPVANKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS +SETSEADRDRAIAEVARSLFDYf +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E8FF61_9PLAN +-sKLERRLKPLIQRHKGQVGAAIKNLRTGESF-TWRADEPMPTASLIKLAVMVEVYRQVE +KKRIDLDDRLRLDEKDKVPGSGVLRLYFSKGLPLRDAVRLMMAVSDNTATNLVLDHI-GL +KATNTTMQRLGHPHTRIHAKVFRRETSIDPERSGSTSATEMVALLEALHSGDLVSAEACV +EMLAHLGACES-TDRIPRYLPTGTKVAHKTGSVAR-VRTDAGIIDSPAG-PIAICVLTAE +NEGPENAAGRLIANVARAAWLHf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI00114D2817 +--TFAKDIEQIENEYNTKVGIYGINTENGKAY-QHNADERFTFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTADNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNESNLS +LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium sp. IITKGP-BTPF85 TaxID=1338009 RepID=A0A0M3CHP4_9SPHI +---LRKNIQQIMQNKDAVVGVAINGINHSDTL-GVNADRRLPMQSVFKFPLAIVMLTEID +KGNFKLDQKIEITKRDLTPWSPIREKYPTGTLTIKEILEYTITLSDNVGCDVLLKLLGGP +QVVESYFAKKGFKDISIKINEKTMQSNWDKQFLNWSTPKEMNRILQTYYVNNLLSMPMYD +FLWTTMKSTNTGLKQLKGQLPDQTVVAHKTGSSGTAALNDVGVVLLPNGEYFVISVFVTH +SKENQETNERIISDIAKAAWDFf +>[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Sphingobacterium sp. JUb20 TaxID=2485110 RepID=A0A4V2TPY3_9SPHI +---LRKNIQQIMQNKDAVVGVAINGINHSDTL-GVNADRRLPMQSVFKFPLAIVMLTEID +KGNFKLDQKIEITKRDLTPWSPIREKYPTGTLTIKEILEYTITLSDNVGCDVLLKLLGGP +QVVESYFAKKGFKDISIKINEKTMQSNWDKQFLNWSTPKEMNRILQTYYVNNLLSMPMYD +FLWTTMKSTNTGLKQLKGQLPDQTVVAHKTGSSGTAALNDVGVVLLPNGEYFVISVFVTH +SKENQETNERIISDIAKAAWDFf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI00130D7E26 +--RLDKEIGGIEEQAKGRLGVALLDLKDRKLW-SHRGAETFPMQSVFKLPLAVAVLQQVE +AGKFRLDQPITVTRKDFSLHSPLAKAFKGERYPLSELIRLAAGESDNTAADLMMREIGGP +QVVTRMLRDGGIEDMSVDRYERQFQPKALTDKRDAATPEASARFLEALAQGNWLRPAHNA +FLTKVITETKVGADRIKAGLPAGSTLAHRTGAGLNHATNDIGIATLPDGRRFVIVTYLAG +ARADAPQREAALAEVARLAVS-- +>[subseq from] Beta-lactamase n=2 Tax=Fibrella TaxID=861914 RepID=I0KGH9_9BACT +--DMQAFMKKMGAEAKGRVGVAAAIVETGESI-AYAGTERFPMQSVYKLPIAMATLAAID +AGTIRRQKPITVGTGDYVGHSPLRDQHPSGAVSIDELLRYAVSESDGSASDVLLRLVGGA +SSVQSYLRTIGVTGVMVRNTERELGSADSVQYANWATPVEMVSLLRQLQLGRGLSDASRT +YLLKLMTDTATGPNRLKGQLPPGTLVAHKTGTSMTAATNDVGLITLPSGKHLAIAVFVSD +ARADQATRERVIAQITKQLWNRw +>[subseq from] Uncharacterized protein n=1 Tax=Stenotrophomonas pictorum JCM 9942 TaxID=1236960 RepID=A0A0R0A388_9GAMM +---LQQELDRLVAGFDGSVGAYVLDLRSGRSA-QVNGDSGFPMASTVKVPVAVHILALVD +EGRLGLQQQVLLEQGDIYPMGGPMDIHLSPGITVRDLLHMMLTVSDNNATDILIRLGGGP +AAVDARMRALGVQGIRVDRYIWEMLSLYNGDPRDTGTPADMAMLLRKIWNGGALKPATTA +VLKQILLDCRTGPGRLKGMLPEATPVAHKTGTVGD-VINDVGVVTLPGGGEVVVAVFLKS +GLGD-HARDRQIAQIARAAHDYf +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WNX8_9BACT +-sALQNQIKEIAAEAKGKVGVTAVVLESGETVaSLNPQEHFPMQSVYKLPISMAVMKAVD +AGKVKLTDKVTISKSEFVGHSPIRDQHPNGALTVEELLRYALSESDGTASDVLMKLAGGP +AAVQA-LTELSIKDLIVLDTEQTFTQDKTAQYRNWATPEAAVALLRALHESRGVSESSQS +LLLKFMTESTPGAKRLKGMLPAGTPVAHKTGTSGTAATNDIGIITLKNGKHVAIALFVSD +SPADQVTREGVIAKIAKAVYD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A6B0XX73_9BACT +---LLAEIERLAPNSGGTVGVGAVHIETGRAV-WFNEDERFPMASTYKVPIAVQLLSRVD +RGEISLADMVELEPADIHPGSGTISNLFDDPLSLRNLLELMLLISDNSATDLTLTAAGGP +DAVNARMAELQVDGLSVDRPTSSLIGAFSTDARDTSTPRAMAHLLAMTWAGKALGSKNTE +VFKDVMLRVQTGTGRIKGVLPPGTPVGHKTGTIG-GTTNDVGYIYLPDGGHVITVVFVKD +SERSVPAREATIAQISRAIYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Porphyrobacter donghaensis TaxID=267135 RepID=UPI00093C0ACA +---LVAELRIIEAAGGGTLGVEIFNTVTGASV-GINQDRRFGHASSFKFSLAAMVLALDA +AGRIDADRQVRWSEADLMWVSPFTRERLSTGATLRELARATQITSDNTAANVLLRELGGP +AGLTAFWRSIGDEVSRLDRYEPEMNLVTAAEYRDTTTPAAMARTVAKIVYGDVLPEKERA +ELKGWMVATETGLKRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKGGPLTFACYFRA +RQEMLASGQETLARVGRII---- +>[subseq from] Serine hydrolase n=1 Tax=Siphonobacter sp. BAB-5405 TaxID=1864825 RepID=A0A2N7B7H1_9BACT +-qRLQQELERMAKLAKGKVGVCALHLESGREI-RMNAKDRFPMASTMKVAVAVELLRKIE +TGELSYLTMTELQPSDLHPGSGTLETLFAKPLSLQNLMELMMVISDNSATDILIRLAGGT +RTVQNRLKALGIEGMSVDRNIIQLIATFDKDPRDTSTPEAMVQLLTQIYQARAVSVASRD +TLLAIMERCRGGQGRLKGYLPPETVVAHKTGTMGASATDDVGIITLPGDGHIAIAVFVGA +SQAPSELREQTIAQISRSVYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas koreensis TaxID=266128 RepID=UPI0007105EEA +--ALQREAQRLVQGLEGEVGVSMIHLQTGRAV-HVNGQRAFPLASVMKLPVAVHILKLVD +EGQLTLGQTVTLTEADIYPMGGPMDLHLSAGISVRDLLHMMITVSDNNATDILLRVGGGT +AAVNTRMQQLGIDGIRIDRYIWELLAAWNADPRDTASTAAIATLLQQVWQGRVLSDGSTA +VLKQIMAQTRTGSGRLRGVLPPRTPVAHKTGTVGD-VINDAGVITLPDGKGEVVVAVLMQ +SSADTAARERTIADLARAAHDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. CECT 9293 TaxID=2675057 RepID=UPI00135DA0E5 +-sTLDQKINSILKDKKATVGISVLGFENGFKY-NKNGNKRLPLLSVFKFHIALAVLNDVD +RGKLSLSQKILVKKTDLLDWSPFRNKYPNGNKSLQELLQYMVSNSDNNITDLLIRLIGGT +QSVQKFMDKMKVQDFTIKADERKMHEGFEFHYWNTSTTNSLNNLLKRFYDGKIVSKNSTS +FLMKTMLETTTGANKIVALLPKETKVAHRTGSSGKNAENDIGIITLPNGNHLALSVLVSD +SMESEVTNTRMVAEIAKIVYQHf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Pedobacter oryzae TaxID=1122943 RepID=UPI00040C97DB +-dSLREKIQQIISTSKATIGVSIIGRNKEDSI-SINGERRFPMQSVFKFHIALAILSQVD +KGKLSLDQKIKIEKKNLLPHSPLREKYPNGALPLAEIISYTVSNSDNVGCDALLRLLGGP +EAVEKYFLRKGFNDISIKINEEVMQNNWELQFQNWTTPKGANKVLEAYYHKKLLSPKSYD +FVWKEMRENESGKNRLKGKLPQGTVVAHKTGSSGTAAVNDIGIVFLPEGEYFFISVFVSN +SKEDFDTNERIITDISKAAWDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium zhairuonensis TaxID=2493631 RepID=UPI001051DE53 +--DLRKELNQIIASKNATVGISVKSIEDKDTL-SINGNLNAPLMSVFKFHIALTVLNKVD +EGKLSLDQKVFIKKKDLHEWSPIRDDYPEGNLTLDKLLRYTVSHSDNNGCDLLIGLVGGT +KEIQKFINKLGIKDFVIKVNEKQMET-WKNLYVNTTTPLATTQLLEKFYKGEILKETTTK +YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISGTNAMNDVGIVKLPNGKHFILSVYLKE +ITETKENTEKIIADITKATWNYf +>[subseq from] Extended-spectrum beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=G9M9P7_9FLAO +---LDEKISAVIKDKKATVGVSVLGFENAFKY-SKNGDKKLPLLSVFKFHLACAVLDMAD +KGKFSTDQKFLIKKSDLLEWSPLREKFPEGNLSLGEIITYTVAQSDNNTCDFLLRLIGGP +QVVQHFMDSKGAKDLQIKYNEDDMHRDWKNQYGNESSTNATVSLLKKFYDGKLLTKKSTD +FLMQIMLGTTTGTNKIVEQLPKSTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVSN +STETEKVNTRMVSDISKIVWDNf +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium hispalense TaxID=1453492 RepID=UPI000493577F +-sALEQKINSIVKNKKATVGVSVLGFEDNFQY-GKNAEKKLPMQSVFKFHIAAAVLDYVD +HGKLSLDQKILLDKTNLLEWSPLREKYPQGNVPLREILEYTVAKSDNNGCDIMLKVLGGT +QNVQKFMDAKGVKGFQIKFNEAEMHKDWNAQYQNYSTASSATDVLKKFHDGKLLSKKSTD +YLMKVMLSTSTGKNKLIEQLPENTPVARKTGASGTGAENEIAIVTLPNGKHYAISVFVSN +STETDVVNCKMISDISKSVWDYf +>[subseq from] Beta-lactamase n=2 Tax=Halieaceae bacterium IMCC3088 TaxID=2518989 RepID=F3L4D6_9GAMM +------ALHTVTSGLVGVAGVAAQDMTTGAQI-FLNGDEPFPMASTYKIAIAMTLLAKVD +HGELNLTDMVDIDDSEWVYSQVIAANFIHQGLSIANLLEVMITQSDNTATDICLRLAGGP +SAVNQYLGQLGIDGMRVDRSTADLLREFEADPLDKSTPRAMLNLLTTLSSGRALSDESTR +LLMDTMMRTVTMPRRLSALLPKNTAIAHKTGTVG-GVANDVGYITLPNGRVFAIAVFTRG +SQSPPSDRERAIAEVARTLYDYf +>[subseq from] class A beta-lactamase n=2 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000DFF6FB4 +--TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS +LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. ZY74 TaxID=2488634 RepID=A0A3N4PYY1_9BACT +--SIYRQIASIAAEAGGEVGVAALNFTTGDSL-RYLDTMRYPMHSVFKFPIAMAILHQVD +EGKLQLHQPVYINKSWLVPWSPLRDSFPNGDKPLSYLLGLMVSQSDNIACDILIDLAGGE +AAINDYVHGLGVQHINIAANEAKMASSWDVQFTNWAYPSAIIQLLDILNKGTALTKTSND +FLWKIMIATTTGPKRIKGLLPPDVVVAHKTGTSGTSATNDAGIIFMPGGEKLAITVFVTN +SKADEATREGVIAKITKLIYD-- +>[subseq from] class A beta-lactamase n=1 Tax=Roseovarius aestuariivivens TaxID=1888910 RepID=UPI00108209A5 +--SVGAAIERVATKLAGRIGFAAQEIGGDEVI-AFNGDETFVMASTYKVAIAAAVLDRVD +KGELSLDQMVDVTLDMMMIGDAALNTHPGLQLSIANVIEVMITESDNTATDISMGLAGGP +AAVTQYLRRIGISDIRVDRPTGEIIGDFEADPRDQATPLAMLQLLLAIDGGTATSAESRN +FLIDVMSRTRTGAGRLKGLLPRGTPVAHKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS +SVTSEADRDRAIAEVARSLFDYf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=A0A4V6IAS9_9FLAO +---LDEKINAVIKDKKATVGVSVLGFENAFKY-SKNGDEKLPLLSVFKFHLACAVLDMAD +KGKFSTYQKFLIKKSDLLEWSPLREKFPEGNLSLGEIITYTVAQSDNNTCDFLLRLIGGP +QVVQHFMDSKGAKDLQIKYNEDDMHRDWKNQYGNESSTNATVSLLKKFYDGKLLTKKSTD +FLMQIMLGTTTGTNKIVEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVSN +STETEKVNTRMVSDISKIVWDNf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A345N8B3_PSEAI +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHRTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Class A extended-spectrum beta-lactamase VEB-25 n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6B9KH37_KLEPN +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHRTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Beta-lactamase n=1 Tax=Dyella sp. AtDHG13 TaxID=1938897 RepID=A0A318E2W6_9GAMM +-dALQHSLEALAQRAPATLGIAVLDLSTGASP-RVNAEVAFPMMSVFKAPVAAAVLSRVD +EGTLSLQQLVSITRDQVQSGSPSVGTHFKGEFTLEQLLKAAVSESDNTAVNALLRTVGGP +DVVTEYFRAHGIEGMRVDMDEAGISRAFLKDPRNRTTPDAAITFLHKLVEGSLLSPASTQ +RLLALMKAQTI-PNRLRAGLPPGVRFADKTGTSGTAAFNDMGIITWPDGHKVLVAAFLMD +SATTAKERDQLFAEIARTVAT-- +>[subseq from] Beta-lactamase n=1 Tax=Aquimarina atlantica TaxID=1317122 RepID=A0A023BW58_9FLAO +-eTLRQKIEGIINSKSAVVGVAINGMETKDTL-SINGQRHFPMQSVFKFPIALTILSEID +KGNLSLEQKIDIKKSELLPWSPIRKKYPEGALTIAEIMKYTVALSDNVGCDVLLKLLGKP +QAVENYFSKLGFKDFSVKINEETMQNNWDLQFLNWTTPKEANKILATFYKNSLLSKKSHE +FVWNVMKGTKTGKNRLRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPNGKYFIISVFITE +SAENFETNEKMISDISKATWDYf +>[subseq from] Class A extended-spectrum beta-lactamase CIA-3 n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=G9MB50_9FLAO +---LDEKISAVIKDKKATVGVSVLGFENAFKY-SKNGDEKLPLLSVFKFHLACAVLDMAD +KGKFSTYQKFLIKKSDLLEWSPLREKFPEGNLSLGEIITYTVAQSDNNTCDFLLRLIGGP +QVVQHFMDSKGAKDLQIKYNEDDMHRDWKNQYGNESSTNATVSLLKKFYDGKLLTKKSTD +FLMQIMLATTTGTNKIVEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVSN +STETEKVNTRMVSDISKIVWDNf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI00114C903B +--TFAKDIDQIENEYNNKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS +LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingosinicella humi TaxID=2068657 RepID=A0A2U2J5F6_9SPHN +---VTPALEALASRAPGQLGAAVLDLGTGEMK-GVNADKPMPMQSVFKLPLAIVVLDLAD +KGKLSLDEEVTLTRDQLSVHSPIADAFPEKTYTIEALMRAAVAQSDNSAADILLKRIGGP +EVVTRFFQDRGIGSFRLDRYEYELQPIYLADPRDRVSPADVVRILSMLAKGELLSPESTE +KLMDILESTSTGTDRLKAGVPDGATVYHKTGTGPASATNDVGIIELADGRRLAVAAFLAG +AELPPEGRAALIAEVARIAT--- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium tenax TaxID=191577 RepID=UPI0004160309 +--ELRKELNGIISTKNATVGVSIKGIEDEDTL-SINGNMKMPMMSVFKFHIALAVLSEVD +KGKRNLKQKFFIKKEDLKKWSPMREEFPDGNVTLDQLLRYTVSHSDNNGCDILLKLIGGT +EAVQKFINKSGIKDFTIKMNEDQMRT-WENLYINTTTPIATTELLEKFYKGNILKKATTK +YLYQIMVECSRGTTWMKAGLPDGTELAHRTGISGTNAMNDIGIVKLPNGRHFILSIYLKN +ITESREDTEKIIADITKATWNYf +>[subseq from] Class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5Q8AMI5_ECOLX +------------------------------------------------------------ +-------NASIILKNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVTGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDEQ--------------- +>[subseq from] Beta-lactamase n=1 Tax=Croceicoccus sp. TaxID=1927144 RepID=A0A2D6EBM8_9SPHN +---FRRKLFAVAPQSQGRIGVAALDLTTGQTV-SIEGDEPFPMASTSKIAIAATFLAGVD +AGKYSLFDRYPLMVPVASESSKVAPVRAGQTMTAETLIERMITRSDNQATDALLAVVGGP +QAVNAWARKAGLNRFRIDRDIATLVRSRHVDVRDSTPPEEMVELIAGLHQGKWLSPASRG +LLIGAMTRTVTGSSRIKAGLPSGVTFGHKTGTLNK-TASDVGFVTMPDGRVVVMAIYVTG +QSGP-AARNAKIAEITRTIYNGf +>[subseq from] Beta-lactamase n=1 Tax=Thioclava arenosa TaxID=1795308 RepID=A0A2A4CMU7_9RHOB +---VGAAIERVATKLAGHIGFAAQEIGGDDVI-AFNGDETFVMASTYKVAIAAAVLDRVD +RGELSLDQMVEVTPDMMMIGDAALNTHPGLQLSIANVIEVMITESDNTATDISMGLAGGP +AAVTQYLRRIGISDIRVDRPTGEIIGDFEADPRDQATPLAMLQLLLAIDSGAATSAESRD +FLVDVMSRTRTGAGRLKGLLPRGTPVGNKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS +SETSEADRDRAIAEVARSLFDYf +>[subseq from] Class A beta-lactamase n=1 Tax=Xanthomonadaceae bacterium NML93-0792 TaxID=2032566 RepID=A0A2A3VMD0_9GAMM +------NAAALEAASGGRLGICLVHPDHRQVM-AHRAREAFPTASTIKFALSAAVLAKSD +AGALSLDDRIPVREQDIRSGAPVSGRHVGKDITVRDLCRGSMVWSDNPAVNLLLPLVGGE +AGLQAFLREHGDTDTDPRGISE---------GRSTTTPLAMAHNLRRFVLDDALSRSSRL +QLADWLIENRTGDARIRAGVPEGWRVGDKTGGMQ-GVSNDIAILWPLRGAPWVLTLYLRD +SPLDAAGRNAVLRRATELAA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium aquaticum TaxID=452084 RepID=A0A0Q3HRQ5_9FLAO +---LEQKLNSITKDKNATVAVSVHSFEDNIKL-SINGDKKLPLLSVFKFHIALTVLNLVD +QKKLSLKQKILVTKGDLHEWSPFRKKYPNGNITLEELLQYMVSQSDNNITDLLIRLVGGT +QSVQNFMDKMKVKDFTIKADESKMHEGYEFHYLNTSTANSLNQLLKNFYDKKIISKSSTS +FLMKTMLETTTGANKIVALLPKETPVAHRTGSSGKNAENDIGIITLPNGKHIALSVLVSD +SMESEETNTKMVAEIAKVVYENf +>[subseq from] Beta-lactamase n=1 Tax=Francisella frigiditurris TaxID=1542390 RepID=A0A1J0KSL4_9GAMM +--QVQNKISKVQGKFGGKIGIYTIDRNNWKNF-KYNENFQFPICSVFKFLVVGAILKESM +ENPGLLDKKIKINEGDIVGYTPVTSKNINKSLSVKDLSKAAI-LSDNTATNLLINELGGL +KKLNEFIISLNDKDTIITANEPNVNNINLHDNFNKTSPKSIARDINKIAFDDVLDKRHQK +LFRKWLKENDTGKNRIAYSLPEGWQIGDKTGTCEYGSTNDVAILWPKGKKAIIMSILYTQ +ADKNAKPKDEIIQATSKIVLDY- +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. MYb7 TaxID=1827290 RepID=A0A2S8ZYC3_9FLAO +---LEQKINSILKNKKATVGVSVLGFENGFKY-NKNADKKLPMQSVFKFHIAVAVLNAVD +QGKLSLDQKIKLDHSNLLEWSPLRDQYAGKEIPLSEVIEYTVAKSDNNGCDILLKLLGGT +QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTTKSAADALKKFYDGKLLSKKSTD +YLMKVMWSTSTGLNKMVEQLPKNTPVARKTGSSGTGAENEIGIITLPNGKHYALAVFVSN +STETDTINCKMISDISREVWEYf +>[subseq from] class A beta-lactamase n=1 Tax=Gluconobacter cerinus TaxID=38307 RepID=UPI000C074E83 +------QIASAEPREQEQSGWWALDLETNRTL-GENPDTHLPMCSTFKWLLAAATLSRTD +YGREHLGREIAFSRKDLISASPEVKAALAASLSVGELCAATVSLSDSTAANLLLKRLGGP +AALTHWLRDHHDPVTRLDRYETALNRVPMGDLRDTTTPRAMVSNLQNMLYGNNLSSASQA +QLLKWLLATTTGPKRMPAGLREGWRIGHKTGTWTRAASGDVAILLPPTGKPVLVAAYAAG +YSIPQSEKEGWFADIAHRAT--- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. AG363 TaxID=2183997 RepID=A0A420CUQ3_9FLAO +---LEQKINSILKNKKATVGVSVLGFENGFTY-NKNADKKLPMQSVFKFHIAATVLNAID +QGKLSLDQKIKLDQSNLLEWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLRLLGGT +QTVQKFMDSKGVQGFQIKYNEEDMHKDWNVQYENYSTTKSAVDILKKFYDGKILSKKSTD +YLMQVLWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGEHYALAVFVSN +STETDAVNCRMISDISREVWEYf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI001431C6C2 +--TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPLAAAQTLNSILTSNEMNESNLS +LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] class A beta-lactamase n=2 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000E67FF07 +--TFAKDIDQIENEYNTKVGIYGINTENGKVY-EHNADERFAFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS +LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter soli TaxID=1739690 RepID=UPI0013696168 +---FERQIAQLADGSAGRIGVAAIDLSTGREI-AVLGDQRFPMASTSKIAIAATYLEGVD +KGRWTLTREWPLMVPVSSRFSTATAPVVPGQMSARQLIDLMITRSSNPATDAMLAAVGGP +AAVNDWARRAGIANFNLTRDIATLVRATYVDIRDSATPRDMVKLLSGLYQGRWLSASSRQ +VLIGAMERCRTGTRRIPALMPERVTVAHKTGSLNN-TSSDVGILTAPDGRTIAVAIYVTG +QG-SKARREAKIASIARAIYDGy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium cucumeris TaxID=1813611 RepID=UPI000787E9EA +-kDLKNKINQIISTKNATVGISLKGIEDKDTL-SINGNKETPMLSVFKFHIALAVLNRVD +EGILKLDQKFFIKKEDLLSWSPIREEYPQGNLTLDQLLRYTVSHSDNNGCDILLNIIGGT +ETVQKFINQQGIKDFTIKVNEKEMSS-FEKCYLNTTTPLATTELLEKFYKGKVLKKETTK +YLYQVMVETSRGLNWMKAGLPVGTELAHRTGISGRAAMNDVGIIKLPNGKHVILSIYLKN +IKEEMADTEKIISDISHAVWEYy +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T3C1_9BACT +-dKLKTEIDSLVKSKNATVGVSIIANNFKDTI-NINENLHYPMQSVFKFPIALAVLSEVD +KGNLKLNQEIIIFSKDLLPWSPIREKFPDGTMTVADIIKYTMAQSDNNGCDILLRLLGGT +TAVEEFLSQHQITDISIKFNEEDMHKEWNIQFQNWATPIALTKLLAKFYVDNILSKESYE +FLWRVMSETTTGTDRLKGQLPQGIIIAHKTGTSGTAAINDIGIIILPNGNPIFISVLVSN +STEDHGVNEKIISDIAKKVWDYy +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus halotolerans TaxID=260554 RepID=UPI000D47A4A0 +------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLT----- +------------------------------------------------------------ +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A3D3QJP0_9BACT +--HLAREVSRLAEHALGTVGVAAYHLETGRWM-TMNGEERFPMASTYKVPIATQILTMVD +KGDLALTDMIEIEREDVYLTSSAISDLLDDPLSIHNLLELMLQISDNIATDILFEIAGGA +EEITGRMVEVGADGIRVDRTTWALIAAFNADPQDTATPLAMARLLRKIWDQEILSEKSSS +LLIDIMYRCQTGEARLKGALPPGTQVAHKTGTIGE-TTNDVGIIDLPDGGHVITVVYIKE +SKPDNPAMEPVIANIARAIHDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium viscerum TaxID=1037377 RepID=UPI0012654A25 +-kDLRNKINEIISTKKATVGISLKGIEDKDTL-SINGNKETPMMSVFKFHIALAVLHQVD +KGRLKLDQKYFIKKEALLPWSPMRDEYPQGNLTLDQLLRFTVSHSDNNGCDILLNIIGGT +EVVQKFINQQGIKDFTIKLNEQEMSS-FDKCYINTTTPLATTELLEKFYKGKILKKETTK +YLYQVMVETSRGLTWMKAGLPIGTELAHRTGISGRAAMNDVGIIKLPNGKHIILSVYLKN +INEEMADTEKIIADISRAVWEYy +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR005 TaxID=1500288 RepID=UPI000646696F +-sALEQKINSIIKDKKATVGISVLGIENDFKY-NKNSDKKLPMQSVFKFHIAAAVLDFVE +KGKLSLDQKIVLDKSNLLEWSPLRDKYPTGNIPLSEILELTVAKSDNNGCDIMLKLLGGP +KTVQKFMDSKGVKGFQIKYNEAEMHRNWNVQYENYSTTQSAVDVLKKFYEGKLLSRKSTD +YLMKVMLSTSTGLNKMVEQLPKSTPVARKTGASGTGAENEIAIVTLPNGKHYAIAVFVSN +SIESDAVNCKIVSDISKAVWDHf +>[subseq from] Beta-lactamase n=4 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2E7_9BACT +-dKLKTEIDSLVKSKNATVGVSIIANNFKDTI-NINENLHYPMQSVFKFPIALAVLSEVD +KGNLKLNQEIIIFSKDLLPWSPIREKFPDGTMTVADIIKYTMAQSDNNGCDILLRLLGGT +TAVEEFLSQHQITDISIKFNEEDMHKEWNIQFQNWATPIALTKLLAKFYVDNILSKESYE +FLWRVMSETTTGTDRLKGQLPQGIIIAHKTGTSGTAAINDIGIIILPNGNPIFISVLVSN +STEDHGVNEKIISDIAKKVWDYy +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR460 TaxID=1500290 RepID=UPI0006489DAA +---LEQKINSIIKDKKATVGVSVMGFENGFKY-NKNAGKKLPMQSVFKFHIAAAVLDYVD +KGKLALDQKVLLDKSNLLEWSPLRDKYPNGDVPLSEILESTVARSDNNGCDIMLKLLGGP +QTVQKFMDSKGVKGFQIKYTEAAMHNDWNAQYENYSTMTSAVDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGKNKLIEQLPKDTPVARKTGASGTGAENEIAIVTLPNGKHYAISVFVSN +STETDVVNCKMISDISKTVWDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. AG363 TaxID=2183997 RepID=A0A420CTJ8_9FLAO +-kDLKNKINQIISTKNATVGISLKGIEDKDTL-SINGNKETPMLSVFKFHIALAVLNRVD +EGILKLDQKFFIKKEDLLPWSPIREEYPQGNLTLDQLLRYTVSHSDNNGCDILLNIIGGT +ETVQKFINKQGIKDFTIKVNEKEMSS-FEKCYLNTTTPLATTELLEKFYKGKVLKKETTK +YLYQVMVETSRGLTWMKAGLPVGTELAHRTGISGRAAMNDVGIIKLPNGKHVILSIYLKN +IKEEMADTEKIISDISHAVWEYy +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. Leaf405 TaxID=1736367 RepID=A0A0Q6B1T2_9FLAO +-sALDQKINSIIKDKKATVGISVLGFENGFTY-HKNGNKKLPMQSVFKFHIAATVLDNVD +KGKLSLDQKVSLNTSNLLEWSPLRDKYPNGNVPLSEILEFTLAKSDNNGCDILLKLLGGT +QTVQKFMDSKGVKGFQIKYNEEVMHKDWNAQYENYSTTASAVDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGINKLIEQLPKNTPVARKTGASGTGAENEIAIVTLPNGKHYAIAVFVSN +STETAEVNCKMISDISKTAWDYf +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter dongtanensis TaxID=692370 RepID=A0A1B2AC19_9SPHN +--RLEAKLRLIEVAAGGRLGVAFVDPVQRLTL-GYRAGERFPMASTFKASLAALLLAKAD +--DVDADRVMRWTEADLQSYAPFAKERLATGATLRELAQAAVEASDNTAANLLLARLGGP +AALTAFWRAFGDDVSRLDDIEPQLNFVPQGDPRNTTTPAAMAGTIGRLLGESVLPVPSRA +SLRKWLAGATTGLTKVRAGVPSTWEAGDKTGNSGY-ARGDIGYVVGPASEPIAFAVYHQS +PVDAAAKVDEAFAEVGRTL---- +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter confluentis TaxID=1849021 RepID=UPI00136C92A0 +--RLAAKLRIIEAASGGVLGVSVRHVGTGRTL-DYRADQRFAQCSSFKFSLAAMVLKMGQ +DGQLDLSEKLHWSRSELMATSPFTASRIDQGATVLELAENTQTYSDNTAANVLLARLGGP +AALTRFWRSLGDDVSRLDRTEPALNNVPPGEIRDTTSPAAMALTTEKILFGDVLSASNSA +LLQQWMADTRTGVRRVRAGLPADWRAGDKTGTSIGGIYVDIGFASPAGTQMLTFATYLRT +IREMDPASEDVLAQVGRVIAQ-- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium indoltheticum TaxID=254 RepID=A0A3G6N4V0_9FLAO +-sALAQKVDSIIKDKKATVGVSVLGFEDAFKY-NKNAETKLPMLSVFKFHIAATVLDLVD +KGKLSLDQKILIKKSDLLEWSPIREKYPNGNLPLSEIINYTVAWSDNNGCDILLRLIGGT +QVVQKFMDSKGVKDFQIKHNEEQMHKGTKYLYENYTTTNSLSQLYKSFYDGKILSEKSTK +LLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN +STETDEVNCKMISNISKAVWDHf +>[subseq from] Class A beta-lactamase n=1 Tax=Flavobacteriaceae bacterium CRH TaxID=1742859 RepID=A0A101CRX8_9FLAO +-nQLREQLNQIIASKNATVGISIKGIEDKDTL-SINGNLKAPMMSVFKFHIALAVLNKVD +DGKLSLTQEIFIKKKDLHEWSPMQKEYPNGNLTLDKLLRYTVSHSDNNGCDILIDLVGGT +KEVQKLINKQGIKDFVIKVNEEQMKT-WKNLYINTTTPLATTELLEKFFKGEVLKENTTK +YLYQIMIETSRGLTWMKAGLPEGTELAHRTGISGTNAMNDIGIVKLPNGKHFILSVYLKN +ITEKQEDTEKIIADIARATWDYf +>[subseq from] Class A beta-lactamase n=2 Tax=Agromyces fucosus TaxID=41985 RepID=A0A4Q2JV61_9MICO +hrRLSDAIAELEQATSVTIGVTAIWHDSRRAF-RYRGDQRFPMCSVFKTLAAGALVQARG +YDEAYWAGPIPFTSADVVGDSTKLDTT-TWTATPEQMADAALRFSDNTAGNLLLRELGGP +QAVTAFARSLGATRTRLDRPEPEVNEATPGDERDTSTPDDIAFLFQKLLIDQGAGALTTA +RLQEWMLRNTTSGKRILAGLTSPFELADKTGLGGYGVVNDAGVIWRPGEEALTLAILTRT +DRADAPSNHDVLADVTRLVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A0U5B2K6_ACIBA +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLLYSVSHSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQVAQTAYQ-- +>[subseq from] Beta-lactamase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E9UZV8_9SPHN +-qDLAARISEXETASGGRLGLALHSPDKGLVX-AYRGDERFAMCSTFKLALAAXTLDXPG +----LREKRLXFGAGDILSYAPYAKERASSGMGGLEAAHHAVTLSDNTAAXLLLAEVGGP +DGFTRWLRSMGDETTRLDRNEPALNENAPGDPRDTTTPTAHADLVGTLLWGDRHAQADRA +LLQEWLVETTTGMNRLRAGLPGEWRAGDKTGTCGQGEVNDIAMFETPDGSRYILAAYLDR +ADGSASDAEARLAEAARAXAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Chitinophaga polysaccharea TaxID=1293035 RepID=UPI0011595B45 +-qTLRQQIAGIAGNISGKVGVYAEVLETKDTV-SFNRDGHFPMQSVYKFPIAMAILHQVD +RRQFRLDQSIHVAKSDLIPASLIRDLHPEGNMALSELISHNIRASDGSACDVLLRLLGGT +AKADAYVHSLGVKQMVIATTEQVQVPNEMIQYKNWATPMAMTQLLKIFYREPVLSDSSKN +YLMDLMITSKPGAKRLKGLLPAGTVVAHKTGTSGTRATNDVGIITLPNGHHLAITVFVSD +SKASEEEREGAIAKIAKAAYDHw +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium viscerum TaxID=1037377 RepID=A0A316WK03_9FLAO +---LEQKIDSILKNKKATVGVSVLGFENGFKY-DKNADKKLPMQSVFKFHIAAAVLNAVD +QGKLSLDQKIVLNKSNLLEWSPLRDKYPEGIIPLSEVIEYTVAKSDNNGCDILLKLLGGT +QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTTKSAADVLKKFYDGKLLSKKSTE +YLMKVMWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN +SMETDAVNCRMISDISKEVWQYf +>[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A411F1X5_ACIBA +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTSGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQVAQTAYQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. ZNC0032 TaxID=1339244 RepID=UPI00068C3062 +-dKLDKAIEGIEQASKGRLGVALMDLRDRKLW-SHRGSETFPMQSVFKLPLAVAVLQQVE +AGKFRLDQPITVTRKDFSLHSPLAKAFKGERYPLRELIRLAAGESDNTAADLLMREIGGP +QVVTRMLRDGGIQGMSIDRYERQFQPNALKDKRDASTPEASAQFLEAFARGNWLRPAHTA +FIEKIVAESKVGTDRLKAGLPAGTRFAHRTGLGLNHATNDIGIATLPDGRRFVIVTYLAG +SRADADERATALADVARLAVS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=G5D8T5_ECOLX +-----------------------------------------------------------N +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKP---------- +----------------------- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium rhizosphaerae TaxID=395937 RepID=A0A3D9D4B0_9FLAO +-eRLRKEIQQIITSKNATVGISIKNIEDRDTL-SINGNSMMPMMSVFKFHIALAVLDQVD +KGKLKLNQKFFIKKEDLLPWSPIQEEFPNGNLTLDQLLKYTVSHSDNNGCDILLRILGGT +EPVQKFINQQGIKDFIIQVNEQQMS-NWDNLYLNVTTPIATTALLEKFYNGKVLKENTSQ +YLYRIMTETSRGLTWMKAGLPDHTELAHRTGISSRAAMNDVGIFKLPNGKHIILSVYLKN +ITEERTDTEKLIADIARATYNYy +>[subseq from] class A beta-lactamase n=2 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000DFEBF5A +--TFAKDIDQIENEYNTKVGIYGINTEKGKAY-QHNADERFAFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS +LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter xixiisoli TaxID=1476466 RepID=UPI00136EBFD7 +-sALEQQIAALAEGSSGRIGVAAIDLSTGQEV-AILGDQRFPMASTSKIAIAATFLEGVD +QGKWSLSSEFPLMVPIRSAFSTTIAPVRQGELTAQTLIDMMITRSSNPATDALLAAVGGP +SAVNDWARRAGINEFQLSRDIATLVRAVSIDVRDSSTPRAMVQLLTGLYQGQWLSSASRH +VVISAMERCRTGTRRIPALMPGGVTVAHKTGSLNN-TSSDIGIITAPDGRSIAVAIYVTG +QG-TRDRREARIANIARAIYDGy +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. CH21 TaxID=713556 RepID=A0A4Q1EU35_9FLAO +---LEQKISTILKNKKATVGVSVLGFENGFKY-DKNADKKLPMQSVFKFHIAAAVLNVID +QGKLSLDQKIKLDQSNLLEWSPLRDKYPGGNVPLSEVIEYTVAKSDNNGCDILLKLLGGT +QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTTKSAVDALKKFYDGKLLSKKSTD +YLMKVMWSTSTGLNKMVEQLPKNTPVAKKTGASGTGAENEIGIVTLPNGKHYALAVFVSN +STETDAINCRMISDISREVWEYf +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. 1_F178 TaxID=2258962 RepID=A0A3D9C4X2_9FLAO +-sTLEQKINSITKGKQATVGVSVLGFENNFKY-SQNGDKRLAMMSVFKFHIACAALDLVD +QGKLSLDQKIFIKKSDLYEWSPYRVKHPEGNATLNEIIDYTVALSDNNLCDLLIGLTGGT +QAIQKFMNSKGIKDFQIKYSEHGMANGWDSLYENYTTTSSTVNLLKKFYDGKLLSKKSTD +YLMQIMLGTKTGANKIVEQLPKGTPAAHKTGSSGRKAENDMGIITLPSGKHYAIAIYVSN +SKESETENCKIISDISKVVWDNf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. 1_F178 TaxID=2258962 RepID=A0A3D9C1F4_9FLAO +-qDLRNKIKTIISTKNATVGISVKGIEDHDTL-SINGNKEMPMLSVFKFHIALAVLNQVD +KGKLKLDQKFFIKKEDLLPWSPIREEYKEGDLTLDQLLRYTVSHSDNNGCDILLKIIGGA +PVVQKFINQQGIKDFTVKLNEQQMNTF-ESYFINTSTPLATTDLLEKFYKGKVLKKETTK +YLYQIMVETSRGLTWMKAGLPTGTELAHRTGISGRAAMNDVGIAKLPNGKHFILSVYLKN +INEEMKDTEKIIADIGSAVWEYy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sporocytophaga myxococcoides TaxID=153721 RepID=UPI00040372CC +-eSLRSDIEALLSTKKAKVGVSIMGDNLRDTL-SINGDQHFPMQSVFKFHIALTVLSQIQ +QGKFSLDQLIKINEDQMLPYSPLREKYPKGVLKISEILEYTVSQSDNVGCDVLLKLIGGP +QVVENFIQEKGFKDFSVKINEEVMQSNWDLQFKNWTTPKTSNQILVFFYNNDNLSPVHHD +FIWTIMKQTETGKNRLKGKLPKGTVVAHKTGWSGTAAVNDIGIIFLPNGRHYFISVFVTD +SKEDTAASEKIIADISKMAWEYf +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. HMWF028 TaxID=2056862 RepID=A0A2R7MVQ8_9FLAO +---LEPKINSILKNKKATVGVSVLGFENGFKY-DKNADKKLPMQSVFKFHIAAAVLNSVD +QGQLSLDQKIKLDTSNLLEWSPLRDKYPEGNVPLSEVIEYTVAKSDNNGCDILLKLLGGT +QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTTKSVADVLKKFYDGKLLSKKSTD +YLMKVMWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFVSN +STETDAVNCKMISDISREVWEYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0D5C9G4_KLEPN +--------------------------------------------------AAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELIAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIG------------------ +----------------------- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium viscerum TaxID=1037377 RepID=UPI0012643E6A +---LEQKINSILKNKKATVGVSVLGFENGFKY-DKNADKKLPMQSVFKFHIAAAVLNAVD +QGKLSLDQKIVLNKSNLLEWSPLRDKYPEGSIPLSEVIEYTVAKSDNNGCDILLKLLGGT +QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTTKSAVDVLKKFYDGKLLSKKSTD +YLMKVMWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALTVFVSN +SMETDAVNCRMISDISKEVWQYf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A126G805_PSEAI +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTAGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0H4IS07_PSEAI +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTAGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium indoltheticum TaxID=254 RepID=A0A381FFG2_9FLAO +-sALAQKVDSIIKDKKATVGVSVLGFEDAFKY-NKNAETKLPMLSVFKFHIAATVLDLVD +KGKLSLDQKILIKKSDLLEWSPIREKYPDGNLPLSEIINYTVAWSDNNGCDVLLRLIGGT +QVVQKFMDSKGVKDFQIKHNEEQMHKGAKYLYENYTTTNSLSQLYKSFYDGKILSEKSTK +FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN +STETDEVNCKMISNISKAVWDHf +>[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=M4QST3_ECOLX +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTAGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma terrae TaxID=1968276 RepID=UPI0013D1CB9B +-qRLYDELERISSLAKGKVGICALHLESGKQI-GLNLQERFPMASTVKVAIAVQLFTLIE +KGQLSLTTMTELQPSDLHPGSGTLETLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT +DAVQKRVKALGINGMSVDRTIIQLIAKIKNDPRDTSTPEAMVDLLTQIYQAKAISPDSRA +LLLGVMERCRGGQARLKGFLPPSTVVAHKTGSLYGSATDDVGIITLPGDGHIAIAVFVGD +SPQPLAEREQTIAHAARAIYDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina megaterium TaxID=1443666 RepID=UPI00046EAE13 +-eTLRQKIEDIINSKNAVVGVAINGMETKDTL-SINGQKHFPMQSVFKFPIALTILSEID +KDNLSLEQKIDIKKSELLPWSPIRKKYPEGGLTVAEIIKYTVALSDNVGCDVLLKLLGKP +QVVENYFSNLGFKDFSVKINEETMQNNWDLQFLNWTTPKEANKILETFYTNSLLSKESHE +FVWSVMKGTKTGKNRLRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPNGKYFTISVFITE +SAESFETNEKMISDISKVTWDYf +>[subseq from] Beta-lactamase class A n=2 Tax=Chryseobacterium carnipullorum TaxID=1124835 RepID=A0A1M7HPI6_9FLAO +-kQLKKDLQQIISTKNATFGISVKGIEDKDTL-SINGNKRMPMMSVFKFHIALAVLDQVD +KGKLKLNQKFFIKKEELHSWSPIRDEFPEGNLTLDQLLRYTVSHSDNNGCDILLEIIGGT +QTVQKFINKKGIKDFTIRFNEQQMSGE--NLYINTTTPIATTELLEKFYKGKVLKKATTR +YLYTIMVETSRGLTWMKAGLPEGTELAHRTGISNRAAMNDVGIVKLPNGKHFILSIYLKD +ITEDRVVTEKTIADIARAVWEYy +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. G0201 TaxID=2487065 RepID=A0A3G6MHT1_9FLAO +---LDQKINSIIKDKKATVGVSVLGFENGFKY-NKNGEKKLPMQSVFKFHIAAAVLDFVD +KGKLSLDQKILLNKSNLLEWSPLRDKYKDTNVPLSEIIDQTVAMSDNNGCDILLKLIGGT +QTVQKFMDSKGVTGFQIKYNEEEMHSDWSFQYKNYSMTNSAVQVLKKFYDGKLLSKKSTD +YLMKVMLGTKTGLNKMVEQLPKDTPVARKTGSSGTGAENEIGIVTLPNGKHYAIALFVSN +STETDAVNCKIISDISKAFWDHf +>[subseq from] Beta-lactamase n=1 Tax=Pararheinheimera tangshanensis TaxID=400153 RepID=A0A5C8LZH2_9GAMM +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSLSHSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSASSQA +LLWKWMVETTTGPERLKGLLPADTVVAHKTGYSGTAATNDIGIILLPDGRSLLVAVFVKD +SAESTRTNEAIIAQVAQAAYQ-- +>[subseq from] Beta-lactamase n=3 Tax=Kozakia baliensis TaxID=153496 RepID=A0A1D8UXU2_9PROT +----KQLISGIERKLGGRVGVSAVDTQTRLIL-QWRGSERFVMHSVFKWLLSAYLLHCSD +TGSRPLQTRVVIKTSSIVGHSDQTKPFVGTAITLETLCLWMMSTSDNGAANTLLDVIGGP +DVLTAWLRSLGDITTRQDTYEPGPTEG-SIDPRNTTTPNAMLALTQKIWLGGVLSPRSRE +TLLAWLRGSAIGGHRLRAGVPSSWVEGDRTGTGDPGVANDVAIFWPDGRRPILVSSFLEG +SANDLARLEDAQASIGRILANLf +>[subseq from] Beta-lactamase n=2 Tax=Staphylococcus edaphicus TaxID=1955013 RepID=A0A2C6WM18_9STAP +---FAKDIDKIEHEYDTTVGVYGINTENGKEY-KHNANERFAFASTYKAIASGILLNNYS +--QVDLNKKVQINQADIVANSPVTEQHIGKTMSLKALIKASMLKSDNTANNKIIEELGGA +TGLKHELELLGDYVSAPQRLEPELNYFDPHSTADTTTPQAAATTLKHILTSNENNKSNVA +LLKQTMIENETGDTLIKAGVPKSYTVGDKSGQGTYATRNDLAFIYPKNQKPIILAIYSKQ +DQKDGKPNDKVISDSAKAVIKH- +>[subseq from] Beta-lactamase class A n=2 Tax=Porphyrobacter sp. LM 6 TaxID=1896196 RepID=A0A1D7NJ85_9SPHN +---LAAELRIIEAAGNGTLGVELYNTVTGLSV-GINRSMRFGHASSFKFSLAALLLARAA +AGTIDADKRVTWTEAEMLEYAPFTRERIATGATLRELAEATQTTSDNPAANILLRELGGP +AALTAFWRSIGDDVSRVDRYEPEMNIVPPAEFRDTTTPAAMARTVAAIIYGNVLPEAERT +MLKGWMVATETGLKRVRAGLPEGWVAGDKTGTSGDGNYIDIGFAEGPKGPPITFACYFRA +RQDDMQARAQLLSRVGRV----- +>[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Mucilaginibacter sp. OK283 TaxID=1881049 RepID=A0A1H8T334_9SPHI +-dRLREKIAEIAKDAKGTIGVSVLNLETGDTL-TYNGYLRQPMQSVMKFPIAITVLHEID +EGKFTLDQLVRLDKSDLFKYSPLQDKYPAANVSIRELLSYMVSLSDNVACDKLLKVLGGT +DAVEAYIHHIGIKNFSIKASEYQMAQAWDVQFTDWVMASELTHLLNVAFKPNFLSAASHT +YLWKIMQETSTGPNQIKGLLPVGTIVYHKTGRSGTNATNDTGIITLPNGNHLAIAILVTN +SPVDLKARELVIARIAKAAYD-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium indoltheticum TaxID=254 RepID=A0A381FCX1_9FLAO +-sALAQKVDSIIKDKKATVGVSVLGFEDAFKY-NKNAETKLPMLSVFKFHIAATVLDLVD +KGKLSLDQKILIKKSDLLEWSPIREKYPDGNLPLSEIINYTVAWSDNNGCDVLLRLIGGT +QVVQKFMDSKGVKDFQIKHNEEQMHKGAKYLYENYTTTNSLSQLYKSFYDGKILSEKSTK +FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN +STETDEMNCKMISNISKAVWDHf +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X6Z9_9BACT +--ALETELRRLAATLPGTVGIAVHHVGTGRLV-TVDAHRAFPMASVFKLPVAIAVLRRVQ +TGGLTLETPITIAPEAYYPYSPLRDAKNRAEVTVRDLVETMMVDSDNTAVDVLMARMGGA +DAVNAELRAAGVPDVSVHRTEGEVMAKFLADSRDTATPTALANLLARLDRGEVLDAERTK +ILVGMLDRNKTGGRRFRAGLPAGVRIGDKTGTNPVGTYNDAALVTLPSGARIALVVMTRE +AGDTGAAAEQLMASVARTVYAHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. s2p32 TaxID=1367558 RepID=A0A0B5EAU4_9PSED +---------------------------TVKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEA---------------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina sp. AU58 TaxID=1874112 RepID=UPI000D6DEB7F +-eTLRQEIENIINSKNAVVGVAINGMETTDTL-SINGQRHFPMQSVFKFPIALTILSEID +KGNLSLEQKIDIKKSELLPWSPIRKKYPEGGLTVAEIMKYTVALSDNVGCDVLLKLLGEP +QTVENYFSNLGFKDFSVKINEETMQNNWDLQFLNWTTPKETNKILATFYKNSLLSKESHE +FVWSVMKGTKTGKNRLRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPNGKYFTISVFITE +SVESFETNEKMISDISKVTWDYf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobacteriales bacterium 50-39 TaxID=1895841 RepID=A0A1M3H3G7_9SPHI +-nALQDSLGTIAKDARGIVGVSLHYKASGRRI-SLHGMEHFPMQSVFKFPLALKILHDVD +NGRFSLDQMIHIDQKDWAPWSPLRDSLNGQTIPLQTLLRYTVSYSDNSGCDILFRLTGGT +RIVNDFIHHTGVKDIAIVATETEMARAWNVQYGNWCTPDAMTALLELFIDGKILKPATTK +ILMQFMINTSTGPGRLKGLLPPGIPLAHKTGTSNTAATNDVGIITLPDGKPLIISVFVKD +AAADEPTRERVIARIAAAAYK-- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium camelliae TaxID=1265445 RepID=UPI000C1C926B +---LNQKIQSIISNKKATVGISVLGFENGFAY-HKNADQKLPMQSVFKFHIAVAVLNIVD +QGKLSLDQKIPLNASNLLKWSPLRDRYPDGNVPVSEILEMTVAKSDNNGCDILLNLLGGT +DTVQKFMDSKGVKDFQIRYSEAQMHKDWNAQYSNYTTAESATDVLKKFYDGKLLSEKSTA +YLMKIMLSTSTGMNKIVEQLPKNTPVARKTGASGTGAENEIAIVTLPNGNHYAIAVLVSD +STESDAVNCRMISDISKAVWD-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium timonianum TaxID=1805473 RepID=UPI00083B9EB5 +-qDLKSKISTIISTKNATVGISLKGIEDKDTL-SINGNKTMPMLSVFKFHIALAVLSQVD +QGKLKLNQKFFIKKEELLPWSPIREEYPEGNLTLDQLLRYTVSHSDNNGCDILLKIVGGA +PVVQKFINQQGIKDFTIRLNEQQMNTF-ESYFVNTSTPLATTNLLERFYKGKVLKKETTK +YLYQIMVETSRGLTWMKAGLPAGTELAHRTGISGRAAMNDVGIIKLPNGKHFILSVYLKN +INEEMKDTEKIIADIGTAVWEYy +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. SLTY TaxID=2683262 RepID=UPI001412E544 +----------AERAAPARLEVAVQNIEGGEMW-ARNAVQAFPMQSVFKAPLGAAVLAEVD +AGRLSLDEVLTLEDMDLSPYSPIAAAWPGRAYTVGELLERAVSDSDNTAADVLMRRIGGP +GVLKAWMVDNGITGIRVDRYERELQTAYMEDPRDTATASGALGFLNKLSSGQLLSPASTT +RLLKLMTDTPRGDTRLKAGLPPGATLAHKPGSSGTAATNDIGIVTLKDGRKYAVVVFLSG +STADQAAQDAIIADAMRIIAR-- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter xanthus TaxID=1784712 RepID=A0A3A1P9H0_9SPHN +---LARQIAQLADGSSGRIGVAAIDLSTGREI-SVLGDQRFPMASTSKIAIAATYMEGVE +QGKWSLSSEFPLLWSVRSTFSTATAPVRKGEMSAAQLIDLMITRSSNPATDALLAAVGGP +QAVNDWMRRAGLEGFQLTRDIATLVRAQHIDLRDSATPQTMVALLTGLYQGQWLSAESRS +VILDAMARCRTGARRIRGQMPGDVSVAHKTGSLNN-TSSDIGIITAPDGRSYVVAIYVTG +QG-SRGNREQRIASIARAIYDGy +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A2W6S9V5_SPHSX +---LRRAVTRFAPATPGHLGVAAIDLESGATL-SIEGDARFPMASTVKIAVAAAFLHQVE +QGRHRLDEMFTLDETMRARSEGITETLPHPGLSALNLLELMLTVSDNTAADMLIGAVGGP +QAVTDWLKASGIEGQRADRSIARLILAFDADPRDSSTPLAMATLLARLHQGKLLSPDHTR +LLFEIMARCKTGKPRVIALLPPDTPWAHKTGTLA-GISNDVGVLTLPNGHHLVVALFAYG +IA-DAAARNRMLADVGRLLYDGf +>[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A357BCM8_9FLAO +-qSLKSNLESIIKDKNATIGVSVWNLEKGEKT-SVNGDSNLPMMSVFKLHIAMTILDLVD +GGTLKLNQKIKFSKSELMQWSPMRDKYPNGGIPLSEMIKYVVAQSDNNTCDILLNKIGGL +KTVENYIHKIGVTDFWAVANEKMMHKVDGAIYKNLTTANASNLLLTKLYTESVLKKNSKD +FLIKIMEETSTGAKRLKGNLPENTVVAHKTGTSGTAATNDIGVISLPNSEHLVISVFVTD +SFENDQTNEKIIADVAKASFDYy +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium jejuense TaxID=445960 RepID=UPI00088C99BC +-sSLEQKINSITKGKQATVGVSVLGFENNFKY-SQNGDKKLAMMSVFKFHIACAALDLVD +KGKLSLDQKVFIKKSELYNWSPFKKKYPEGNIPLSEVIDYTVALSDNNLCDILIELVGGT +QAVQKFMNSKGIKDFQIKHSERGMASGWDSLYENYTTTHSTVQLLKQFYDGKLLSKKSTD +YLMKTMLGTKTGTNKIIEQLPKGTPAAHKTGSSGTIAENDMGIITLPNGKHYAIAVYVSN +SKESEAENCKIISNISKAVWDNf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B2CD74_KLEOX +--------------------------------------GRFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVQDHY--------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Oxalobacter formigenes TaxID=847 RepID=C3X3G3_OXAFO +--ALQAKVDAIVKQTQAEVGVAIESGGSAVKA-AHNADKPFPMQSVVKFPVALAVLDSVD +KGRLNLDDPVFLAPSDLLPHSPLREKYPEANIPLREILSDTITLSDNNGCDILLRLLGGP +QAVDRYIKGLGITGMEIGATEADMHRDPEKQFRNTATPAAANRLLRLFYRKKLLKPSSQE +LLWKLMGDTLTGPGRLRDPLPAGTALIHKTGTGAGMSVNDIGIIMLPDGRPVLISVFISE +AKDSILETEKTIAALSRAAWE-- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. Gsoil 183 TaxID=1807141 RepID=A0A5D8ZVV7_9FLAO +---LEQKIHSILKNKKATVGVSVLGFENGFKY-DKNSDKKLPMQSVFKFHITAAVLNSVD +QGKLSLDQKIVLNQSNLLEWSPLRDKYPAGNIPLSEVIEYTVAKSDNNGCDILLKLLGGT +QTVQKFMNSKGVKGFQIKYNEEAMHKDWKVQYENYSTTKSAVDVLKKFYDGKLLSKKSTD +YLMQVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYAIAVFVSN +SMETDAVNCRMISDISKEVWEYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacterium faecium TaxID=34087 RepID=UPI0012912D4F +---LRKNIQQIMQNKDAVVGVAINGINHSDTL-GVNADRRLPMQSVFKFPLAIVMLTEID +KGNFKLDQKIEITKRDLTPWSPIREKYPTGTLTIKEILEYTITLSDNVGCDVLLKLLGGP +QVVESYFAKKGFKNISIKINEKTMQSNWDKQFLNWSTPKEMNRILQTYYVNNLLSMPMYD +FLWTTMKSTNTGLKQLKGQLPDQTVVAHKTGSSGTAALNDVGVVLLPSGEYFVISVFVTH +SKENQETNERIISDIAKAAWDFf +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium joostei TaxID=112234 RepID=A0A1N7HXD5_9FLAO +-qDLRNKINTITSTKNATVGISVKGIEDKDTL-SINGNKETPLMSVFKFHIALAVLNRVD +KGKLKLNQKFFIKKEDLMPWSPIREEYPEGNLTLDQLLRYTVSHSDNNGCDILLNIIGGT +DSVQKFINQQGIKDFTIKVNEQQMSS-FDKFYLNTTTPLATTDLLEKFYKGKVLKKETTK +YLYQIMVETSRGLTWMKAGLPAGTELAHRTGISSRAAMNDVGIVKLTNGKHFILSVYLKN +INEEMAVTEKIIADISHAVWEYy +>[subseq from] Uncharacterized protein n=1 Tax=Rubrivirga marina TaxID=1196024 RepID=A0A271J5B7_9BACT +--ALADEVERLAAPAEGRVGVGIALLGSDEAV--VVGEGRHPMQSVFKLPLGMAVLAAVD +RGELSLDRRVAVTLADFVSHSPIRDRHPDGVLSVGELLGAAAGGSDGTAADVLLDLLGGP +AEVEGFLRGIGVEGVDVAVTEKDMGRDYDAQYRNGATPAGALALLRALHAGRGLSQESRT +LLLRVLTETTTGPNRLRGRLPEGTPVAHKTGTSRTAATNDVGLVTLPDGRRLAVAVFVSD +SPADDATRERVIADVARAAYDAw +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000254AF75 +--TFAKDIDQIENEYNTKVGIYGINTEKGKAY-QHNADERFAFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV +NSLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS +LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYTTRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma endophyticum TaxID=662367 RepID=A0A1I1Q3U2_9BACT +-qRLQQELERIAKLAKGKVGVCAVHLESGKQV-SLNLQERFAMASTIKVAIAVQLFTKIE +KGELSLSTMTELKPSDLHPGSGTLDVLFAKPLSVENLLELMMVISDNSATDILIRLAGGT +EAVQNRLKTLGIQGMSVDRTIIQLLAKFKYDLRDTSTPEAMVNLLTQIYRGKAITPASRD +TLLAVMQRCRGGLNRLKGYLPPETIIAHKTGSLDGNATDDVGIITLPGDGHIAIAVFVGP +SPQPLDVREQTIAHVSRLIYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Brucella melitensis TaxID=29459 RepID=UPI000C05D189 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEL------- +------------------------------------------------------------ +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E6MJ04_9BACT +--HLAXEVSRLAEHALGTVGVAAYHLETGRWM-TMNGEERFPMASTYKVPIATQILTMVD +KGDLALTDMIEIEREDVYLTSSAISDLLDDPLSIHNLLELMLQISDNIATDILFEIAGGA +EEITGRMVEVGADGIRVDRTTWALIAAFNADPQDTATPLAMARLLRKIWDQEILSEKSSS +LLIDIMYRCQTGEARLKGALPPGTQVAHKTGTIGE-TTNDVGIIDLPDGGHVITVVYIKE +SKPDNPAMEPVIANIARAIHDYf +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus nepalensis TaxID=214473 RepID=A0A291JNQ7_9STAP +---SAKTFEQIEQDNDTIVGVYGVNTANGKHI-QHRSDERFAFASTYKAIASGILLQNTA +--TSTLNKKIDIKKDDIVANSPVTEKYVGSQMTLKALIQASMLQSDNTANNKIINEIGGI +KGFHEELKQLEDNISNPQRLEPELNLYDPTSTADTTTPKAAAMTLKHILTNEDMSKANRN +LLKNVMIHNETGDTLIKAGVSKQAVVGDKSGQGTYGTRNDLAFIYPKNQEPIVLAIYTKK +DGKDAKPNDKVIQMATKTAME-- +>[subseq from] Beta-lactamase n=2 Tax=Firmicutes TaxID=1239 RepID=A0A380GQT3_9STAP +---SAKTFEQIEQDNDTIVGVYGVNTANGKHI-QHRSDERFAFASTYKAIASGILLQNTA +--TSTLNKKIDIKKDDIVANSPVTEKYVGSQMTLKALIQASMLQSDNTANNKIINEIGGI +KGFHEELKQLEDNISNPQRLEPELNLYDPTSTADTTTPKAAAMTLKHILTNEDMSKANRN +LLKNVMIHNETGDTLIKAGVSKQAVVGDKSGQGTYGTRNDLAFIYPKNQEPIVLAIYTKK +DGKDAKPNDKVIQMATKTAME-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2E6RZ35_9SPHN +----SATFRILERALGGRLGVAFHAPARHAHI-AYRGDERFPMCSTFKTSLAAQVLSLGE +DGTLDLSERVTWTADDLIFHTPFTGERVAQGATLSELAHAAQTVSDNLAANLLLDRVGGP +AGLTAFWRRLGDETSRLDRMETAVNFVPEGDVRDTTTPVAMARTLAKMLATNPLAAPRRR +ELRQWMIESTTGLKRVRAGLPEDWVAGDKTGNSGY-LRGNIGFALDPSEAPTFFAVYHQS +PVIDGQRVDAAFAQVGRLLA--- +>[subseq from] class A beta-lactamase n=1 Tax=Gluconobacter sp. DsW_058 TaxID=1511210 RepID=UPI000A37660C +-----SQIASAEPREQEQSGWWALDLETNRTL-GENPDMHLPMCSTFKWLLAAATLSRTD +YGREHLGREIAFSRKDLIAASPAVKDALAASLSVGELCAATVSLSDSTAANLLLKRLGGP +AALTHWLRDHHDPVTRVDRYETALNRVPMGDLRDTTTPRAMVSNLQNTLYGNNLSSASQA +QLLKWLLATTTGPKRMPAGLRDGWRIGHKTGTWTRAASGDVAILLPPKGKPVLVAAYAAG +YSIAQSEKEGWFADIAHRAT--- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter longus TaxID=1044 RepID=A0A074MSA0_ERYLO +---YAAMLRQIEGEFGGTLGAEFVDVTSGQAV-GLNSDVRFGHCSSFKLSLAAKILQRDV +SGEDSAERRVTWSEDDLMSVSPFTTRTLSQGATLRELAEATQKYSDNAAANILLREIGGP +AALTAFWRSLGDDVSRLDRYEPTLNLVPPTEVRDTTTPAAMARTVAKLVYGDALPEADRA +TLRQWMVDTPTGLDRVRKGLPEEWLAGDKTGTGLGGIYIDIGFVQPPERGAMTYAAYYRP +AGTDNTYD--------------- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. KBW03 TaxID=2153362 RepID=A0A3N7AXZ5_9FLAO +-kDLRNKINEIISTKKATVGISLKGIEDKDTL-SINGNKETPMMSVFKFHIALAVLHQVD +KGKLKLDQKFFIKKEALLPWSPMRDEYPQGNLTLDQLLRFTVSHSDNNGCDILLNIIGGT +EVVQKFINQQGIKDFTIKLNEQEMSS-FDKYYINTTTPLATTELLEKFYKGKILKKETTK +YLYQVMVETSRGLTWMKAGLPTGTELAHRTGISGRAAMNDVGIIKLPNGKHVILSVYLKN +INEEMADTEKIIADISRAVWEY- +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium piscium TaxID=333702 RepID=A0A3D9BN89_9FLAO +---LAQKVDSIIKDKKATVGVSVLGFEDGFKY-NKNAETKLPMLSVFKFHIAATVLDLVD +KGKLSLGQKILIKKGDLLEWSPIREKYPNGNLPLSEIINYTVAWSDNNGCDILLRLIGGT +QVVQKFMDSKGVKDFQIKHNEEQMHKGAKYLYENYTTTNSLSQLYKKFYDGKILSEKSTK +FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN +STETDEVNCKMISDISKAVWDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. 1335 TaxID=2183928 RepID=A0A3D9P5C3_9FLAO +---LEQKINSIIKDKKATVGVSVLGFENGFKY-NKNSEKKLPMQSVFKFHIATAVLDFVD +KGKLSLDQKILLNKSNLLEWSPLRDKYPNGNVPLSEILEYTVAKSDNNGCDILLKLVGGP +HVVQKFMDSKRVTGFQIKYNEAEMHKDWNVQYENYSTTNSAVQILKKFYDGKLLSKKSTD +YLMKIMLSTSTGLNKLVEQLPKNTPVARKTGASGTGAENEIAIVTLPNGKHYAISVFVSN +SMESDAVNCKMISDISKTVWDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Alcaligenaceae bacterium TaxID=2021368 RepID=A0A4Q3ZNF4_9BURK +----------------------------------------------------AHVLKRVD +EGQEKLDRPLSYSADDLLTYAPVTRANVTKKMSVSELAAAAVQVSDNTAANLLFRTQGGP +TGLTQFLRNLGDSITRSDRIEPELNTA--SGDADTTTPKAMSETLRTLFEKETLQPSSLA +LLKGWMLTNTTSAHRLKAGLPANWKVADKTGTGGQGNVNDVGIVYTPDGAAIYVAVFISE +SKKPTDELEAAIADVAREI---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B2CD70_KLEOX +--------------------------------------GRFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVQDH---------------------------------------------- +----------------------- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. CBTAP 102 TaxID=2135644 RepID=UPI000D751195 +-sALDQKINSIIKDKKATVGVSVLSFESNFKY-SKNGDKKLPLLSVFKFHLASTVLDMAD +KGKFSTDQKFLIKKSDLLEWSPLREKYPEGNLSLGEIIKYTVAQSDNNTCDFLLRLIGGP +KVVQQFMDSKGVKDLQIKYTEDDMHKDWKNQYGNESSTNSTVVLLKKFYDGKLLSKKSTD +FLMQIMLATTTGTNKIVEQLPKRTPVAHKKGSSGTVAENDMGIITLPNGKHYAIAIFVSN +STETERVNTRMVSDISKIVWDNf +>[subseq from] Serine hydrolase n=1 Tax=Chelatococcus sp. TaxID=1953771 RepID=A0A2W6XX53_9RHIZ +--ALDREIARIERDAKGRLGVALIDLKDRESW-SHRGAEPFPMQSVFKLPLAVAVLQAVE +AGKLRLDQPITITRKDVSLHSPIAERFKGDSYPLRELLRLSTAESDNTAADLLMRLVGGP +EAVTAMLKQGDVAGLSIDRYERVFQPASLTDRRDSATPDGSAAFLEALAKGNWLRPAHTA +LLVKMATETKSGPQRLIAGLPKGARLAHKTGLGPNHATNDIGIVTLPNGRVFAIAVYLAG +SQATATEREAAHAAVARAAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000A524614 +--TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNESNLS +LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNNLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma panaciterrae TaxID=496058 RepID=UPI00037D8305 +-qRLERELDRIATLAKGKVGICALHLESGKQV-SLNVQERFPMASTVKVAIAVQLFTLIE +QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT +EAVQKRINALGIQGMSIDRTIIQLLAKLATDPRDTSTPEAMVNLLTQIYRGTALKPESRA +LLLGVMERCRGGAARLKGYLPPNTVIAHKTGSLNGIATDDVGIITLPDEGHIAIAVFVGD +SPMPLADREQVIAQSARAIYDFf +>[subseq from] class A beta-lactamase n=1 Tax=Gluconobacter frateurii TaxID=38308 RepID=UPI000C0784DD +-----ARLRAIEQSAGGRLGAFVLDTGSGRSF-GWRMDERFCHCSTFKLSLAAMVLREND +AGRLDLSETLAVSRADIVAYSPVVEENLAKGLSFLTLAQAVQITSDNAAANVLLRRFGGP +EAVTRFWREIGDSTSRLDGYEPSINVIPPGTDKNSTTPRIMAETVRKIVLGNVLGTANRE +RLQGWMASTKSGLNRIRGGIPSSWGGFDKTGTGMGNKTNDLAVLIPPDHSPLIVTGYFEN +PADVRPADEAVLKALGEVAV--- +>[subseq from] class A beta-lactamase n=1 Tax=Lutibacter sp. SG786 TaxID=2587130 RepID=UPI00141F2BDC +--HLRDTLAQLAERAPGTLGVTVVDLETHDRT-RINADRGYPMMSVFKAPVAAAVLAEVD +AGRVALDQEVTIDRKDVVGGSPSIGAHFAGRFTVDRLLVAAVSESDNTAVDALIRLLGGP +AVVTRYLRDHGIDGMRVDLSEGDVSHAFMADARNTTTPDAAADFLEKLSRGKLLSADSTQ +RLLRLMYDQTV-PNRMRAGLPPDLRFADKCGTSYTAAFNDIGIVTWPDGHTVVVAAFLTG +SRADANTRNALFADIARAVA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. CH25 TaxID=713559 RepID=A0A4Q1FNY6_9FLAO +-qDLRSKINTIISTKNATVGISVKGIEDKDTL-SINGNKEMPMLSVFKFHIALSVLNQVD +KGKLKLNQKFFIKKEELLPWSPIREEYPEGNLTLDQLLRYTVSHSDNNGCDILLRIVGGA +PVVQKFINQQGIKDFTIRLNEQQMNTF-ESYFVNTSTPLATTDLLEKFYKGKVLKKETTK +YLYQIMVETSRGLTWMKAGLPAGTELAHRTGISGRAAMNDVGIIKLPNGKHVILSVYLKN +INEEMKDTEKIIADIGTAVWEYy +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=A0A2T4LTS6_9STAP +---AAKSFDQIEQDNDTIVGVYGINTANGKVI-QHRSDERFAFASTYKAISSGILLQNTP +--TSELNKKITISKDDIVAYSPVTEKYVGKQMTLRALIKASMLQSDNTANNKIIEEIGGI +KGFQQALKQRGDNISNPQRLEPDLNLYDPQSTADTTTPKRAATTLNHLLASENMSRPNLE +LLKHTMIHNETGDTLIKAGMSKDDVVGDKSGQGTYGSRNDLAFVYPKNQKPIILAIYTKK +TDKDAKPDDKVIQTAAETAIK-- +>[subseq from] Beta-lactamase n=2 Tax=Chryseobacterium koreense TaxID=232216 RepID=A0A0J7IXK9_9FLAO +-qSLRNEISKLTKGKNATVAVAVKGIDFPVEFnNENAGKKLPMQSVFKFHIALAVLDWVD +QGKLALDQKVFINKSELLPWSPIREKNPEGNMPISELIEYAVAMSDNVGCDVLLRLIGGP +KTVNDFLISKGMKDTQIVYNEEVMQSDWKNQYENYTTMKSSNTLLKDFYQGKIISKESTE +FLLGVLYRTSTGTNKIVEQLPKSAKVAHKTGSSGTGAENDIAIITLPNGKTYALSIFVSD +SMESWETNCKIISNISKAVYD-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000D1FB0C0 +--TFAKDIEQIENEYNTKVGIYGINTENGKVY-EHNADERFAFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKTSMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS +LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] Class A beta-lactamase n=1 Tax=Francisella endosymbiont of Amblyomma maculatum TaxID=255919 RepID=A0A1E7UB04_9GAMM +--QVTNDIQNIEKKYGGKIGVYIINRNDWSNF-AVNASFYFPICSIYKFLVLGAILKQSM +ADNKLLNQKVKISKNQIVGYSPITRKHINQTMTVKQLCKASMQ-GYNTATNILIEKLGGL +KNLNKFILSLADHVTKIVNLEPKVNHVSLITNENKTTPKIMARDINKLAFSDALDKKHCL +MFKKWLIASSTGNNSIGAEIPDEWEVGDKTGTCQYGTTNDIAIIWPDDNRAVIMAIFYTK +SQKNAKPNSKILREVTKILLD-- +>[subseq from] uncharacterized protein LOC111067177 n=1 Tax=Drosophila obscura TaxID=7282 RepID=UPI000BA0DE7F +------------------------------------------MCSTFKASLAACVLSRID +QGHDTLEITLSFSATDIKDYAPVAKANLARGLTLRDLCAGAVEQSDNVCANLLLTHIGGP +SALTAFWRALGDTTTRLDAYEPELNRTPLGRLENTTTPTAMTSVLRAITLGPALSAPSRA +LLVQWMIACQTGTHRLRAGLPKHWVVGDKTGNNGKDAAGDIAIIWPKSDTPLLVSAYTRG +GKPTETDFATAFAAIGSLVA--- +>[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Sphingobacterium faecium TaxID=34087 RepID=A0A2T5YBK1_9SPHI +---LRKNIQQIMQNKDAVVGVAINGINHSDTL-GVNADRRLPMQSVFKFPLAIVMLTEID +KGNFKLDQKIEITKRDLTPWSPIREKYPTGTLTIKEILEYTITLSDNVGCDVLLKLLGGP +QVVESYFAKKGFKDISIKINEKTMQSNWDKQFLNWSTPKEMNRILQTYYVNNLLSMPMYD +FLWTTMKSTNTGLKQLKGQLPDQTVVAHKTGSSGTAALNDVGVVLLPSGEYFVISVFVTH +SKENQETNERIISDIAKAAWDFf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Runella sp. CRIBMP TaxID=2683261 RepID=UPI001411C655 +---LRKKIQQIASKTDGTLGVGILGLENRDTL-TLNNHVHFAMQSVYKFHLGLAILNQVD +KGNLKLNQKILIQKKDLLPWSPLREKYPNGNIPLSELFQFTVAQSDNNGCDILFRIMGGP +RVVDNYIKSIGMTDVSIRTTEEEMHKTEGAQFTNWTTPWSAVQLLEKFYQKKILSPTSHA +FMWKVLTEANTGSGKIKGLLPEGTLVAHKSGLSGTAATNDIGIVTLPNGKHFIISIFYGN +TKLSDKESDKVIAEVTKAAWDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina sp. AU58 TaxID=1874112 RepID=UPI000D6E5452 +---LRKTIEQIVSDKNAVVGVSIIGNNGTDTL-SLNGDKRFPMQSVFKFHIALAVLAEVD +KGTLSLDQTVEIGKDELLPWSPLRDENPNGGFTIKRLIQYNVSHSDNTACDILIRLIGTP +KTVEEYIKKSGIEDIQITFNEEGLQAKWENIFQNWTTPNAASETLKLFFENNLLSKSSYD +FFWETNIDTKTGKNRIRGQLPKEIIVANKTGWSGTAAVNDIGIVFLPNGNYFVVSVFVTD +SQEDFKTNAKIIADIAKATYDFy +>[subseq from] Beta-lactamase class A n=1 Tax=Bosea sp. TND4EK4 TaxID=1907408 RepID=A0A1N6U757_9BRAD +--ALDKGVAKIERRAKGRLGVALIDLKDHKLW-SYRGAETFPMQSVFKLPLAVAVLQQVE +AGKLRLDQPVSVTRKDLSLHSPLARQFKGESYPVQELIRLAAGMSDNTAADRLMREIGGP +QVVTAMLRAGGVQGLSVDRYERQFQPEALKDKRDASTPEASARFLEGFAEGNWLRPAHTA +FLTKIITETPIGADRIKAGLPAGSTLAHRTGAGLNHATNDIGIAALPDGRRFVIAIYLAG +SRVDANEREAALAEVAKLAVS-- +>[subseq from] Beta-lactamase n=1 Tax=Actinobacteria bacterium TaxID=1883427 RepID=A0A2E8M085_9ACTN +----SATFRILERALGGRLGVAFHAPARHAHI-AYRGDERFPMCSTFKTSLAAQVLSLGE +DGTLDLSERVTWTADDLIFHTPFTGRRVAQGATLSELAHAAQTVSDNLAANLLLDRVGGP +AGLTAFWRRLGDETSRLDRMETAVNFVPEGDVRDTTTPVAMARTLAKMLATNPLAAPRRR +ELRQWMIESTTGLKRVRAGLPEDWVAGDKTGNSGY-LRGNIGFALDPSEAPTFFAVYHQS +PVIDGQRVDAAFAQVGRLLA--- +>[subseq from] Uncharacterized protein n=1 Tax=Prosthecomicrobium hirschii TaxID=665126 RepID=A0A0P6VMJ4_9RHIZ +-----RKVGEVAADVGGRLGVGILDLKSGQDW-YLAGDERFPMQSVFKAPLGVAVLRQVD +RKKLGLDQTVTITRRDVAMWSPIAKDMAGDRVAVRELVRGAVSLSDNTAADVLMRLIGGP +AAVTAALMESDIAGLRVDRYERELQPYLSTDERDTATPKAAVAFLAKLDRGAMLSADMTA +VMIRAMAESPTGAQRLKAGLPAGARLAHKTGTGPNAATNDIGIVTLPGGAKFAIAVFLAG +SALPEAQREAVHARVMAILAE-- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. GH3-10 TaxID=2691582 RepID=UPI0013653783 +---LERRIAQIADGSDGRIGVAAIDLVSGEEV-SVLGDQRFPMASTSKIAIAATFLEGVD +KGRWSLTSEFPLMLAVRSPSTRVAPVRAGQHMPAHQLIDLMITRSSNSATDALLAAVGGP +SAVNDWARRAGLKDFSLDRDIATLVRTYHIDGRDSATPQAMVRLLAGIYQGEWLSPQSRE +VILDAMERCRTGRRRIPAMIPAGATVAHKTGTLNR-MAGDIGIVEMPDGRAIALAIFVTG +QSASRRRRDARIASIARALYDGf +>[subseq from] Class A beta-lactamase n=1 Tax=Porphyrobacter sp. TH134 TaxID=2067450 RepID=A0A2N4WT61_9SPHN +---LAAELRLIEAAGNGTLGAELYDTRSGMSV-GLNADRRFGHASSFKFSLAALLLQRHA +AGMIDADRRVMWTQADMIAHAPFTTERMASGASLRELARATQTTSDNPAANILLRELGGP +AALTAFWRSIGDDVSRLDRYEPEMNLVPPAEFRDTATPAAMARTVAKIVYGDVLPDAERA +ELKGWMVATETGLKRVRAGLPQGWAAGDKTGSSGY-NYVDIGFAEGPKGPPITFACYFRA +RQAEQARAELALSRIGRII---- +>[subseq from] class A beta-lactamase n=1 Tax=Gluconobacter japonicus TaxID=376620 RepID=UPI0007C74462 +-----ARLRAIEQSAGGRLGAFVLDTGSGRSF-GWRMDERFCHCSTFKLSLAATVLREND +AGRLDLSETLAVSRADIVAYSPVVEENLAKGLSFLTLAQAVQITSDNAAANVLLRRFGGP +EAVTRFWREIGDSTSRLDGYEPSINVIPPGTDKNSTTPRIMAETVRKIVLGNVLGTANRE +RLQGWMASTKSGLNRIRGGIPSSWGGFDKTGTGMGNKTNDLAVLIPPHGSPLIVTGYFEN +PADVRPADEAVLKALGEVAV--- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina TaxID=290174 RepID=UPI000941F285 +-eTLKQKIEDIINSKNAVVGVAINGMETKDSL-SINGQRHFPMQSVFKFPIALTILSEID +KGNLSLEQKIDIKKSELLPWSPIRKKYPEGALTIAEIIKYTVALSDNAGCDVLLKLLGEP +QAVEHYFSKLGFKDFSVKINEETMQNNWDLQFLNWTTPKEANKILATFYKNNLLSKEGHE +FVWSVMKGTKTGKNRLRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPNGKYFIISVFVTE +SVENFETNEKMVSDISKAAWDYf +>[subseq from] class A beta-lactamase n=2 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000ACB6059 +--TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYIGKTMSLKTLIKASMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNESNLS +LLKQTMIENKKGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] Serine hydrolase n=2 Tax=Halioglobus TaxID=1217416 RepID=A0A3L7DVI9_9GAMM +--KVAAALEAVTAGLVGVVGVAAQDMAGGTQV-FLNGDQPFPMASTYKIPIAVALLSKVD +AGELSLTDMIEIDDGEWVYSQVIAANFIYQGLSVANLLEVMITHSDNTATDVCLRLAGGP +AAVNRRLAQLGIEGMRVDRSTGDLLRRFEADPLDKSTPSAMLNLLISLYNGSALSEKSTE +FLLGTMARTVTMPDRLGGLLPRNTPVAHKTGTVG-GVANDAGYITLPDGRRFAIVVFTRG +SDTPPADRERAVAEVARTLYDYf +>[subseq from] Beta-lactamase n=1 Tax=Runella sp. SP2 TaxID=2268026 RepID=A0A3G3GXS4_9BACT +--DLKKKISQIVAGKKVKVGVAILGPTPADTL-SFYGNGRFPMQSVFKLHIGLAMLSEVD +KGKFKLNQPIKVEKADLIPYSPLRDAHPNGGIELSKIIEYTVAESDNVGCELLLKLLGGP +QAVEQYLLSRGFKNVSIKINEQVMQKNWELQYQNWTTPKAANDLLAAYYFRKLLSSKSHD +FLWSVMKGTKTGKNRLRSQLPAETVLAHKTGSSGTAAVNDIGVLFLPSGSPVFISIFVTN +STESEATNEKIIADIGKVTWDYf +>[subseq from] Class A beta-lactamase n=1 Tax=Porphyrobacter sp. HT-58-2 TaxID=2023229 RepID=A0A2L0GI50_9SPHN +---LAAELRIIEAAGGGTLGVEIYDTVSGMAV-GINRDRRFGHASSFKFSLAALLLQRHA +AGLIDADRRVTWSEADLLAHAPFTRERLATGATLRELARATQVTSDNPAANILLRNLGGP +AGLTAFWRSIGDEVSRVDRYEPEMNNVPTAEFRDTTTPAAMARTVAKIVYGDVLPEAERA +ELKRWMVETQTGLKRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKGPPLTFACYFRA +RQSED------------------ +>[subseq from] Uncharacterized protein n=2 Tax=Stenotrophomonas sp. Leaf70 TaxID=1736233 RepID=A0A0Q4QH23_9GAMM +---LQRELDRLIAPFDGKVGAYVLDLRSGRSA-QVNGGSGFPMASTVKVPVAVHILALVD +EGRLDLRQQVLLQAADIYPMGGPMDIHLSAGITVRDLLHMMLTVSDNNATDILIRLGGGP +AAVDARMRALGIGGIRVDRYIWEMLALYNQDPRDTSTPAGMAELLRRIWEGRALRPDTTA +VLKAILLDCRTGQGRLKGMLPEATPVAHKTGTVDE-VINDVGVITLPGGGEMVVAVYLVS +GAGD-QARDRMIAQVARAAHDYf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDE0539 +-dRLHSELAALASVHPGRVGICVQD-EDLAPI-CVNGEQRFSLQSVMKVVVAAAVMQAVD +ERRISLADRVTIRREDLSVIQPIADIVAERGTNIGDLVRRAVVESDSAATDVLISQLGGV +KAVQAFLNEAGLPDIRIDRTERELQTAYLQDPRDTATPRDMVGFLHMLAAGQLLSASSTA +YLLDVMSETITFPDRLRAGLPSDWTIGHKTGTSQNGVTNDVGILTAPDGRHVAIAAFVAE +STANKDDRAATIAAAARAVTAAy +>[subseq from] Beta-lactamase class A n=1 Tax=Bosea sp. BK498 TaxID=2512178 RepID=A0A4V3BXJ3_9BRAD +--SLDKGIAKLERRTEGRLGVALIDLKDHKLW-SWRGAETFPMQSVFKLPLAVAVLQQVD +AGKFKLDQPITITRKDLSLNSPIARQFKGESYPVRDLIRLAAGQSDNTAADRLMREIGGP +QVVTKMLRDGGIENMSVDRYERQFQPAALKDKRDAATPEASARFLEGFAEGNWLRPAHTA +FLTKVISESKIGTGRIKAGLPPGSVLAHRTGLGLNHATNDIGIATLPDGRRFVIVTYLAG +SRADAPKREAALAEAARLAVS-- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. G0186 TaxID=2487064 RepID=A0A3G6P9V7_9FLAO +---LEQKITSITKGKKATVGVSVLGFEDSFTY-SKNGDKRLALMSVFKFHIACAALDLVD +KGKLSLDQKIFIKKSELYEWSPFREKYPHGNATLGEIIDYTVALSDNNLCDILIELVGGT +QAVQQFMNSKGVTDFQIKNSEHDMAKDWKSLYENYSTTNSSVQVLKKFYDGKLLSKKSTD +YLIQIMLGTKTGTNKMIEQLPQGTPVAHKTGSSGTVAENDMGIITLPNGKHYALAVFVSN +SKESEAVNCRIISDISKTVWNHf +>[subseq from] class A beta-lactamase n=1 Tax=Gluconobacter oxydans TaxID=442 RepID=UPI00062C2A5F +-------IASAEPREQEQSGWWALDLETNRTL-GENPDMHLPMCSTFKWLLAAATLSRTD +YGREHLGREIAFSRKDLIAASPAVKDALAASLSVGELCAATVSLSDSTAANLLLKRLGGP +AALTHWLRDHHDPVTRLDRYETALNRVPMGDLRDTTTPRAMVANLQNTLYGNNLSSASQA +QLLKWLLATTTGPKRMPAGLREGWRIGHKTGTWTRAASGDVAILLPPSGKPVLVAAYAAG +YSIPQSEKEGWFADIAHRAT--- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium nakagawai TaxID=1241982 RepID=A0A3N2F7Q6_9FLAO +-sTLEQKINSITKGKQATVGVSVLGFDNNFKY-SQNGEKRLAMMSVFKFHIACAALDLVD +QGKLSLDQKIFIKKSDLYEWSPYRVKHPEGNATLNEIIDYTVALSDNNLCDLLIGLTGGT +QAVQKFMNSKGIKDFQIKYSEHGMANGWDSLYENYTTTSSTVDLLKKFYDGKLLSKKSTD +YLMQIMLGTKTGANKIVEQLPKGTPAAHKTGASGRKAENDMGIITLPSGKHYAIAVFVSN +SKESETENCKIISDISKVVWDNf +>[subseq from] class A beta-lactamase n=1 Tax=Francisella sp. SYW-9 TaxID=2610888 RepID=UPI00123D1E67 +--QTNDSFKSLEKQYNGKLGVYSINTPNKTSF-SYNENYHFPICSVFKFLLVGAILEKDM +HNKGFLEKKTLISEQDVKGYTPVTGKNINKSLTISELCFAAI-LSDNAAANILVEQIGGI +KEVTKFAKKLGDHDTIIKDDEPKVNYTSPDSNINKTTPKAITSDLYKLVSGDILDKKHKE +IFIQYLQKNYTGKNRIAVGMPKNWIIGDKTGTCGYGATNDIAIIWPQNSEPFALGMMYTD +PTKKASSNEKIIQQAAKIV---- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. CA7 TaxID=2604424 RepID=UPI001295C31D +-eNLRKEINRIITAKNVTAGISIKNIENEDTL-SINGHMSMPMMSVFKFHIALAVLDQVD +KGKLKLYQKFLIKKEELLPWSPIRDEFPDGNLTLNQLLRYMVAHSDNNGCDILLRMIGGP +EFVQKFINKQGIKDITIKLDEEQMGKAWENLYVNVTTPEATTLLLEKFYNGKILKENTTD +YLYRIMVQTSRGLTWMKAGLPPGTELAHRTGISGRAAMNDVGIFKLPNGQHIILSVYLKN +IKEERADTEKIIADIANATYNYy +>[subseq from] Class A beta-lactamase n=1 Tax=Gluconobacter cerinus TaxID=38307 RepID=A0A1B6VM78_9PROT +------QIASAEPREQEQSGWWALDLETNRTL-GENPDTHLPMCSTFKWLLAAATLSRTD +YGRDHLGREIAFSRKDLISASPAVKDALAASLSVGELCAATVSLSDSTAANLLLKRLGGP +AALTHWLRDHHDPVTRLDRYETALNRVPIGDLRDTTTPRAMVANLQNTLYGNNLSSASQA +QLLKWLLATTTGPKRMPAGLREGWRIGHKTGTWTRAASGDVAILLPPSGKPVLVAAYAAG +YSIPQSEKEGWFADIAHRAT--- +>[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas nitritireducens TaxID=83617 RepID=UPI000AA8A980 +---LQRELDRLIAPFDGKVGAYVLDLRSGRSA-QVNGGSGFPMASTVKVPVAVHILALVD +EGRLDLRQQVLLQAADIYPMGGPMDIHLSAGITVRDLLHMMLTVSDNNATDILIRLGGGP +AAVDARMRALGIGGIRVDRYIWEMLALYNQDPRDTSTPAGMAELLRRIWEGRALRPDTTA +VLKAILLDCRTGQGRLKGMLPEATPVAHKTGTVDE-VINDVGVITLPGGGEMVVAVYLVS +GAGD-QTRDRMIAQVARAAHDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella sp. enrichment culture clone MS32-6A TaxID=979975 RepID=F1CKJ5_9GAMM +----------------------------------------FAMCSTSKFMAASAILKQSE +TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP +RKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGE-------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Aureicoccus marinus TaxID=754435 RepID=UPI000CF41E2F +--RLLDQIAAVDKNLDGQLGFSVLHLESGQEI-SHFGNKRFPMQSVYKFPIALVMLQAVD +RGEFSLDQMVEISPSEYIPHSPLRDRFPRGTMSIKELLRYNISESDGTACDVLLRLLGGT +KETEKKLHALGITDMAIATTEMVQMKNDTIQYQNWATPRGMNQLLKVFHQGEVLSEPSGN +LLKEFMSISTWFDRRLKGKLPPGTKLIHKTGTSNNRATNDVGIIELPNGEHLAVSAFIMD +SRDQHQERENAIAQAARLAYNFw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=T1Z245_ECOLX +------------------------------------------------------------ +-------QRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMEQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILV----- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Scytonema millei VB511283 TaxID=1245923 RepID=A0A1D2P6D4_9CYAN +----QERLKNLDSAAQGKVGIGVLDLNSGQSW-FLNGKQRFPMQSVYKLPSAIAVLKQVD +EGKISLKQLVTIMRRDLAPASPIIKELKGDRIPLRNVLEGSVGISDNTAADALVRLLGGT +KQVNAILGKLQIRNIRVDRLEQQMQPKYLTDPRDTATPEGMVNLLARLQSNQLLSENSTA +LLLKIMTDSPTGQKRLKAGLPENWSIAHKTGTGAGTATNDVGIASSPDGKRVAIAVFIAG +SKAPLEEREKVMSNIASRVVQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDBE152 +--KLDEGIVAIEKEAEGRLGVALLDLKDRKSW-SHRGAETFPMQSVFKLPLAVAVLQQVE +AGTFRLDQPITVTRKDFSLHSPLAKAFKGERYPLSELIRLAAGESDNTAADLMMREIGGP +QVVTKMLRDGGVTGISIDRYERQFQPNALADPRDASTPEASAQFLEALARGSWLRPAHNA +FLMKVITETKVGGARIKAGLPAGSQLAHRTGAGLNHATNDIGIATLPDGRRFVIVTYLAG +SRAEAAEREAALAAVARLAVS-- +>[subseq from] Class A beta-lactamase n=1 Tax=Candidatus Aminicenantes bacterium TaxID=2052149 RepID=A0A497E0S8_9BACT +--RLKAQLEEVIKTIQGEVGVAVKYLKTGEEL-NINGETSFPMASVFKVPILVEVMAQIK +EGRFSLDDEISLQPADLHLGSGLLNDLEAPGLSVRNLIYLMMLISDNSATDILLTKV-GP +DKVNQRLRSLGIDGITVNRTCQHLILQFARIPQDQSTPLAMARLLELIFTKQILDEPSCD +FIIKVMLRCQTGERRLRGDLPASVQVAHKTGTIG-GTVNDAGVIFLPNQGRVVIVVFTKG +TDEKTEDVERVIAQIARFVYDYf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides uniformis TaxID=820 RepID=A0A174LPE0_BACUN +-sELENRIDSLLKGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNADIIARISRMVYDA- +>[subseq from] Beta-lactamase class A n=2 Tax=Parasphingorhabdus marina TaxID=394732 RepID=A0A1N6F9T3_9SPHN +--AARREIAAIEKQTGGRVGVALTSRSGETDF-SWRGGERFAMCSTFKAPLAFALFDAVE +KRDLDLDARFALKKSDLVPYAPYVEKRLAEDVSFMQLAKAAVAISDNAAANLILKAIGGP +AGFTRFVRNHGDEITRLDRIEPFLNENKPDDPRDTTSPEAFASLMHSLMIARP-KHKHST +TVYDWMANSPTGRNRIRLGLPYGWPVGTKTGTAAGGAVNDVAIFWPSGDEPRILSVYWDR +PTVSRVETELAMARIAKIA---- +>[subseq from] Beta-lactamase class A n=1 Tax=Bosea sp. 1131 TaxID=1871628 RepID=A0A2S4M879_9BRAD +--RLDQEIAAIERQSQGRLGVALLDLKDRKSW-SHRGSETFPMQSVFKLPLAVAVLQAVE +AGSLKLDQQITITRKDFSLHSPLAKAFKGESYPLRELIALAAGESDNTAADTLMRLIGGP +QVVTKMLRDGGIGGISVDRYEREFQPLALKDPRDAATPEASTLFLEALAKGNWLRDPAHA +FLDTVITQTKTGPLRIRAGLPLGARFAHKTGAGLNHATNDIGIVTLPNGRVFAIAIYLAG +SKADEKGREAAHAAVAKAAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Taibaiella koreensis TaxID=1268548 RepID=UPI000E59AE0F +-eALRQSIQAIVDTARAHIGIGVLDLDTGDSL-LYNGADTFPMQSVFKFPLAVAMLHQIE +QEKKPLSTLVNLSRKTMDPWGPLLKEHKEEHITIGDLLDYSVKKSDNNACDALFRLAGGT +GTVNRYIRSLGITGMTIRATEAEMRTAWPVQYTNSCRPGAMLQLLQQFYRKKLLSPEHQQ +FLWQIMTDSENPSDRIKGLLPANAVVTHKTGTSDTNATNDVGIISLPNGKHIALVVFVSD +FKGGTARAAHLIALVAKAVWDHy +>[subseq from] Serine hydrolase n=1 Tax=Bosea sp. RCAM04685 TaxID=2283844 RepID=A0A370L0G5_9BRAD +-aKLDSEIPKIEQQSGGRLGVALIDLKDRKTW-SHRGKEPFPFQSVFKLPLAVAVLQAVE +AGKFKLDQSITVTRKDLSLHSPLAKAFKGESYPLRDLLTRATGDSDNSAADLLLRLVGGP +QALTKVLRDGGVTGISVDRYERVFQPASLNDSRDSATPEASIAFLDGFAAGNWLREPEHT +RLIDIITETKSGPDRIRAGLPKGAGFAHKTGLGPNHATNDIGIVTLPNGRRFAIAVYLKG +ATADAKAREAAHAAIARLAVT-- +>[subseq from] Class A beta-lactamase n=1 Tax=Altererythrobacter sp. AY-3R TaxID=2268576 RepID=A0A4Q2KL53_9SPHN +---FKQQIARLADGSNGRIGVAVLDLATGQEF-SILGDQRFPMASTSKIAVAATFMEGVE +QGRWSLSSEFPLLIPARSEFSSVKAPVRKGKLPASQLIELMITRSSNPATDALLAAVGGP +EAVNDWMRRAGIEEFQLTRDIATLVRATAIDIRDSATPRAMTQLLAGLYQGRWLSKRSRE +VILGAMERCITGKRRIPALLPAGVTVAHKTGSLNN-TSSDIGIVRTPGGQAFAVAIYVTG +QG-TRPARENRIAQIARAVYSGy +>[subseq from] Uncharacterized protein n=2 Tax=Arsenicibacter rosenii TaxID=1750698 RepID=A0A1S2VNQ4_9BACT +--RLQAEINQVISRKKATVSVGIYDIGSRQSL-YINGDKYAPMQSVYKFHVALAVLKEVD +KGRFRLTQKMRIRKSDLVPYSPIGEAHPNGVLPLSEIIRYMVAESDGSACDYLFRLLGGT +KPVNDFIHQLGVWDVFIAATEEKMQANWDVQYTNRTTQKAMISLMKLFYEKKILSPASHT +FLWDVMLSTVTGPDRLKKGLPAGTPIAHKTGTSGMGAVNDAGFMTLPNGKHVAISVFVTN +STEGIEANERIIADIAKLTYAYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dyadobacter tibetensis TaxID=1211851 RepID=UPI00046EE21F +-qQLRTEIKAILDESDGLVGVGVVDFETNESI-YFNAQERFPMQSVFKFPLALAVLQRVD +AGEWSLDMPIEVTPADLLPWSPIRERYPNGNLTLAEIIRYTVAQSDNNGCDILFRLLDGP +IEVNKAVAQMTSKGIAIVADEAGMAKGWDVQFGNYSTPVAMMDLFQKFWAGRILSPASTE +YLKKVLFETNTCEACMKGLLPKGAQVAHKTGRSATAATNDAGVLLLPNGKAVGLVIFVSN +SKASDSARERLIARISKAVWDQy +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. Root672 TaxID=1736584 RepID=A0A0T2Q8I9_9SPHN +-nALAQQIALIAEGSQGRIGVAAVDLTTGQEI-GVLGDERFPMASTSKIAIAATFLEGVD +RGRWSLDSQFPMMMPVASKSSRIAPVRAGESYSARALIDMMITRSNNQATDALLAAVGGP +SKVNDWARRAGIQNFNLTRDIATLVRAAHIDIRDSATPRDMVKLLSGIYQGQWLSASSRY +VIIDAMERCRTGTRRIPALMPADARVAHKTGSLNN-TSSDIGIITMPDGRAIALAIYVTG +QG-TRLNREARIANIARAIYDGy +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. Leaf258 TaxID=1736310 RepID=A0A0Q6JLI7_9NOCA +--DVSTGLQAVEERYDVTVGVSLLNTGTGETI-SYRGAERFGFASTVKVFLAAEFLRRTP +--EDARDDLVRWTAADIERYSPVTTARLDTGLTAAELAEAAVRESDNTATNLVFDQIGGP +AELDAALSRLGDDVTDIVDVEPGLNTVGPDSTGNTTTADAFTTSLAALRGAGSSTDADAA +TLAEWMSGNATGDALVRAGAPSGWTVADKSGGAG-AVRNDIAVVTPPGRPPLVLTVLTRK +NDASAPYEDAAVSESAAVVLN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=B2CD53_ECOLX +--------------------------------------GRFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVQDH---------------------------------------------- +----------------------- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. ZT4R6 TaxID=2593302 RepID=A0A552UXA1_9FLAO +--TLQKEIEDIIKNKKATVGVSIIGNNLKDTV-SINATNHLPLQSVYKFHIAIAVLSEVD +EGKFQLNQKIKLTHTDLLKWSPMRDDYPNGALSLAKILEYTLVQSDNNGCDILLRLLGGP +KFVDNYFIKNNFKNISIKATEEDMHKDWETQFKNWTTPKSATEVLIAYYNKKLLSQDSYN +FLWTTLKATTVGAKRIKGQLPKGTIVAHRTGTSGTNATNDIGVVFLPNGKYFFISVFVSN +SKEDNATNEKIIADIAKAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. Hurlbut01 TaxID=1681828 RepID=A0A0K9XW47_9FLAO +---LEQKLNSITKDKNATVAVSVHSFEDNIKL-SINGDKKLPLLSVFKFHIALTVLNLVD +QKKLSLKQKILVTKGDLHEWSPFRKKYPNGNITLEELLQYMVSQSDNNITDLLIRLVGGT +QSVQNFMDKMKVKDFTIKADESKMHEGYEFHYLNTSTANSLNQLLKNFYDKKIISKSSTL +FLMKTMLETTTGANKIVALLPKETPVAHRTGSSGKNAENDIGIITLPNGKHIALSVLVSD +SMESEETNTKMVAEIAKVVYENf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. HTF TaxID=2170732 RepID=A0A2U1R483_9FLAO +--DLRKELNQIIATKNATVGISIKSIEDKDTL-SINGNLKAPLMSVFKFHIALTVLNKVD +EGKLSLDQKIFIKKKDLHEWSPMRDDYPEGNLTLDKLLRYTVSHSDNNGCDVLIKLVGGT +KEIQKFITKQGIKDFVIKVNEQQMET-WKNLYINTSTPLATTELLEKFYKGEILKESSTK +YLYQIMTETSRGLTWMKAGLPEGTELAHRTGISGTNAMNDVGIVKLPNGKHFILSVYLKE +ITETKEDTEKIIADITKVTWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000983540E +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTG--------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter atlanticus TaxID=1267766 RepID=A0A0F7KWQ3_9SPHN +---FERQIAQLADGSNGRIGVAAIDLATGEQL-AVLGDQRFPMASTSKIAVAAAFLEGVD +QGRFSLTSEYPLLLPVNSQSSPVAPVRKGKYLQARELIHLMLTRSSNSATDALLAAVGGP +NVVNDWVNRAGITEYNLTRDIATLVRAVQIDTRDSATPKAMVQLLRGLYQGRWLSPESRD +FLIRTMEECRTGTRRIPANLPGDVTVAHKTGSLNN-TSSDVGILTAPDGRTIALAIYVTG +QG-SRLNREHKIASIARAIYDGy +>[subseq from] Uncharacterized protein n=1 Tax=Bosea sp. Root381 TaxID=1736524 RepID=A0A0Q9IJQ3_9BRAD +-aKLDKEIVAIEREAKGRLGVALLDLKDRKTW-SHRGNESFPMQSVFKLPLAIAALQAVE +AGKLKLDDKITIRRSEFSLHSPLAKAFKGESYTLRELIRLTAAESDNTAADNLMRRIGGP +KVVSEMLRAGGIEGISIDRYEREFQPASFKDKRDKATPGASVLLLEAVAKGNWLREPSHS +ALIKHMLDNAGGRERIRAGLPEGSRYAHRTGAGLNHATNDIGIVTLPNGRVFAIAVYLAG +SKADAKAREAAHAAVARLAVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Porphyrobacter donghaensis TaxID=267135 RepID=UPI000A3865C3 +---LAAELRIIEAAGNGTLGVELYNTATGQSV-GLNSDRRFGHASSFKFSLAALLLQRHA +AGLIDADRRVTWSEADMLEYAPFTRERIATGATLRELARATQITSDNPAANILLRELGGP +AGLTAFWRSIGDEVSRVDRYEPEMNLVPSTEFRDTTTPAAMARNVAKIIYGDVLPDAERA +ELKQWMVETETGLNRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKGPPITFACYFRA +RQ--------------------- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X203_9BACT +--ALETELRRLAATLPGTVGIAVHHVGTGRLV-TVDADRAFPMGSVFKLPVAIAVLRRVQ +TGGLTLETPITIAPEAYYPYSPLRDAKNRAEVTVRDLVETMMVDSDNTAVDVLMARMGGA +DAVNAELRAAGVPDVSVHRTEGEVMAKFLADSRDTATPTALANLLARLDRGEVLDAERTK +ILVGMLDRNKTGGRRFRAGLPAGVRIGDKTGTNPVGTYNDAALVTLPSGARIALVVMTRE +AGDTGAAAEQLMASVARTVYAHf +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E7S2J0_9PLAN +--RLAARIKPLVSRHKGQVSVLVKHLGSGRSF-AWKSDRPMPTASLIKLAVMVEVYRQVE +KGRVDLDDRLKLDEDDKVPGSGLLRKYFTAGLTLRDAVRLMIAVSDNTATNLVLDHI-GL +ESTNRTMSRLGHLNTRIHAKVFRRETSIDPDRSGSTTASETVSLLEAIHRGKLVSESASQ +QMLEHLKACES-AERIPRFLPSGTVVAHKTGSVSQ-VRTDAGIIDSPAGG-IAICVLTSK +NAGPANAASRLIADISREAFLHf +>[subseq from] FTU family class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI000158B396 +--QLDDSFKNLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM +HNQGFLDKKIPINQNDIGKYAPITAKNVGKTLTISQLNYAAI-LSDNPAANILVRELGGL +QNLNKFIKKLGDNDTIITADEPEVNYTQPHSNINKTTPKAITKDIYKLAFGNILDKKHKD +IFIKYLQDNNTGANRIAFGMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN +PNKNAPSNEEIIQQAAKLIAN-- +>[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Sunxiuqinia elliptica TaxID=655355 RepID=A0A4R6GUS0_9BACT +---LRDEINQILKDKSATVAVAIQGTEMHDTL-SINADRHMPMQSVFKFHLALAVLEQID +QGKLSLDHQLSFDKNRVDRYSPLREKYPQGAVSVAELLKYTVSLSDNLGCDLLFQLVGGP +EVVQSYLHQIGIKDIAIVYNELLMQSDWSHQYQNWTTAHATNQLLQLFFESQLLSTENHQ +FLLDILKGTTTGKKSIRGLLPKDAVVAHKTGHSGTGALNDIGIVFLPNGSYFYLSILVSD +SMEDNKTNQQLIAQISKLAWDYf +>[subseq from] Beta-lactamase n=1 Tax=Bosea sp. BIWAKO-01 TaxID=506668 RepID=A0A1E1V3C5_9BRAD +--KLDSGIQAIERDARGRLGVALIDLKDRKSW-SHRGQERFPMQSVFKLPLAVTVLQAVE +AGKLRLDQEILVKRNELALWSPMKKGFKGEEYTVTDLLTRSTGASDNSAADVLMKRIGGP +KVVTTMLNEGGLSGISVDRYEREFQPYINGEARDSATPEASIAFLEGLVRGNWLREPADR +LLTGILLKSPTGAQRIRAGLPTGATFAHKTGTGDNSAINDIGIVALPDGRRFAIAVYLAG +AQADATAREAAHAAVAKLAVE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Mesorhizobium sp. TaxID=1871066 RepID=A0A3S3JR79_9RHIZ +-dRLHSELAALADAHPGRVGICVQD-ETSPPI-CVNGEQRFSLQSVMKVIVAAAVMKAAD +ERRIALEDRVTIRREDLSVIQPIADIVAERGTSVGDLVRRAVVESDSAATDVLISHLGGV +NAVQAFLDEAGLRGIRIDRTERELQTAYLKDPRDTATPRDMVGFLHRLATGQLLSASSTA +HLLEVMNGTVTFPDRLRAGAPSGWTIGHKTGTSQNGVTNDVGILTAPDGGRVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] class A beta-lactamase n=2 Tax=Staphylococcus TaxID=1279 RepID=UPI00068A408A +--TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA +--PSELNKKVETNESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS +LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium hankyongense TaxID=1813876 RepID=A0A328AV99_9CAUL +-kQLNGDIAAIAARLPAVLGAGLMNLESGEVW-SLNGERPFPMQSVFKAPLGAYALSEVD +AGLLSLDQVFTLDDIDLSPYSPIADAWPARRYTARELLVAAVGMSDNTAADILMRRVGGP +GALTAWLVGKKIEEVRVDRYERELQPRYLADPRDTATPRGMLTFLGMLAAGELISRASTA +LLLQIMTNTPTGAHRLKAGLPPGATLAHKTGTARTDAINDVGIVTLPDKRAYAAAVFLSG +STLDDAARDAAIADVARAMI--- +>[subseq from] class A beta-lactamase n=1 Tax=Bosea sp. AS-1 TaxID=2015316 RepID=UPI0012FD8EF9 +--RLDKEIGGIEEQAKGRLGVALLDLKDRKLW-SHRGAETFPMQSVFKLPLAVAVLQQVE +AGKFKLDQPITVTRKDFSLHSPLVKAFKGERYPLSELIRLAAGESDNTAADLLMREIGGP +QVVTKMLRDGGIEGMSVDRYERQFQPKALVDKRDAATPEASARFLEALAQGNWLRPAHNA +FLMKVITETKIGADRIKAGLPAGSKLAHRTGAGLNHATNDIGIATLPDGRRFVIVTYLAG +SRADAPQREAALAEVAELAVS-- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR561 TaxID=1500298 RepID=UPI0006469793 +---LDQKINSIIKDKKATVGVSVLGFENGFKY-SKNADKKLPMQSVFKFHIAAAVLDFVD +KGKLSLDQKIALNKSNLLEWSPLRDKYPNGGVPLSEILEMTVARSDNNGCDIMLNLLGGT +QTVQKFMDSKGIKGFQIKYNEEAMHKDWNVQYENYSTMNSVTDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGLNKLIEQLPKNTPAARKTGASGTGAENEIAIITLPNGKHYAIAVFVSN +SMETDTFNCKMISDISKTVWDYf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SSP7_9BACT +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMAQLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNADIIARISRMVYDA- +>[subseq from] Class A beta-lactamase n=1 Tax=Pseudomonas sp. SST3 TaxID=2267882 RepID=A0A658G377_9PSED +--ALTQTVASIEARTGGHIGVSVTALESGQSW-SHRGDERFPIASTFKAFFMRPPTCFGC +RDEVELDTRVRFDETDLQSYSPITKDRVGGNMSLFELCSATTSMSDNTAANLILRNTGGP +QGFTTFMRSIGDAVTRLDRYEPELNDVGPGEKRDTTTPRAAARSLETLLLGDSLSTDSRE +QLKAWLINNKVGGPLLRASLPESWKIADRTGSGG-------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Oerskovia enterophila TaxID=43678 RepID=A0A161XB32_9CELL +-hELDEALRDLERSRSLTVGVSVRG-GGRADY-GYRAAERFPMCSLFKPIAVGALLADKA +YDDAYWSREIAFGPEDLVENSPVTSATTTWRMTPAQLADAALRFSDNTAGNLVLREIGGP +TAVTSFAASLGARATRLDRIEPQLNEATPGDDRDTSTPDDVARIYGALLLERGAGALTAA +RLGDWMLRSTTSGKRFRAGLDGTYELADKTGAGGYGVVNDAGVLWRPGVEPTTLVVMTRT +DSPGATWDDEAVAAITRLVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium taiwanense TaxID=363331 RepID=A0A0B4DA44_9FLAO +---LDQKINSIIKDKKATVGVSVLGFENGFKY-SKNADKKLPMQSVFKFHIVAAVLDFVD +KGKLSLDQKIALNKSNLLEWSPLRDKYPNGGVPLSEILEMTVARSDNNGCDIMLNLLGGT +QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTMNSATDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGLNKLIEQLPKNTPAARKTGASGTGAENEIAIITLPNGKHYAIAVFVSN +SMETDAVNCKMISDISKTVWDYf +>[subseq from] Beta-lactamase n=2 Tax=Jannaschia seohaensis TaxID=475081 RepID=A0A2Y9B554_9RHOB +--SVGAAIERVATKLAGRIGFAAQEIGGDDVI-AFNGDETFVMASTYKVAIAAAVLDRVD +KGELSLDQMVDVTLDMMMIGDAALNTHPGLQLSIANVIEVMITESDNTATDISMGLAGGP +AAVTEYLRRIGISDIRVDRPTGEIIGDFEADPRDQATPLAMLELLLAIDSGAATSAESRD +FLIDVMSRTRTGAGRLKGLLPRGTPVGNKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS +SETSEADRDRAIAEVARSLFDYf +>[subseq from] class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI0010236BAA +------------------------------------------------------------ +-------------QNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRVVFIYTAG +SQAILVERNRTIAEV-------- +>[subseq from] Class A beta-lactamase n=1 Tax=Bosea sp. TaxID=1871050 RepID=A0A521LS37_9BRAD +--ALDKGVAKIERRAKGRLGVALIDLKDHKLW-SYRGAETFPMQSVFKLPLAVAVLQQVE +AGKLRLDQPVSVTRKDLSLHSPLARQFKGESYPVQELIRLAAGMSDNTAADRLMREIGGP +QVVTAMLRAGGVQGLSVDRYERQFQPEALKDKRDASTPEASARFLEGFAEGNWLRPAHTA +FLTKIITETPIGADRIKAGLPAGSTLAHRTGAGLNHATNDIGIAALPDGRRFVIAIYLAG +SRVDANEREAALAEVAKLAVS-- +>[subseq from] Beta-lactamase n=1 Tax=Runella sp. HYN0085 TaxID=2259595 RepID=A0A344TH98_9BACT +---LRQKIQQIASKTDGTLGVGISGLENRDTL-TLNNHIHFAMQSVYKFHLGLAILNQVD +KGNLKLNQKILIQKKDLLPWSPLREKYPNGNIPLSELFQFTVAQSDNNGCDILFRIMGGP +RVVDNYIKSIGMTDVSIRTTEEEMHKTEGAQFTNWTTPWSAVQLLEKFYQKKILSPASHA +FMWKVLTEANTGSGKIKGLLPTGTIVAHKSGLSGTAATNDIGIVTLPNGKHFIISIFYGN +TKLSDKESDKVIAEVTKAAWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI000E69494F +---AAKSFDQIEQDNDTIVGVYGINTANGKVI-QHRSDERFAFASTYKAISSGILLQNTP +--TSELNKKITISKDDIVAYSPVTEKYVGKQMTLRALIKASMLQSDNTANNKIIEEIGGI +KGFQQALKQRGDNISNPQRLEPDLNLYDPQSTADTTTPKMAATTLNHLLASENMSRPNLE +LLKHTMIHNETGDTLIKAGMSKDDVVGDKSGQGTYGSRNDLAFVYPKNQKPIILAIYTKK +TDKDAKPDDKVIQTAAETAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI001247CD0B +--TFAKDIEQIENEYNTKVGIYGINTENGKAY-QHNADERFTFASTYKAIASGILLNKVA +--PSELNKKVEINESEIVANSPVTEQYLGKTMSLKALIKTSMLQSDNTANNKIMQELGGV +NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS +LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ +DQKDAKPNDKVISDSAREVIKY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Hymenobacter sp. TaxID=1898978 RepID=A0A519YV03_9BACT +hpALRATIDRLATGDAGKVGVALQVLETNDTL-SYHNRQPYPMLSVFKLAIAMQVLHEVD +RGHLRLAQQLLLTKADLPGHSPLRDKYPGGNVSIQELLTYMVTVSDNNACDVLLRLVGGP +SKLTAYVRQLGVRPFVAEVSEAQMGAVWANQYRNWSYPSTQVDLLVQVYHRTALSQASSA +LLWQLLLDTSVGPQRIKGLLPAGTPVAHRTGTSGTNALNDAGVITLPNGQHVALTVFVAD +SPADTATRELLIATIARAVYD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6LYZ9_9BACT +-------------------GVAAWRLDHGPRF-LLNADEAFPMASTFKVAVAGALLAKID +AGTLSLETVLPVDKSRYVESEVIADALIHSGLSIHNLLELMLTRSDNTATDVLTSAAGGP +TAVTAWVRAQGITGLRVDRDTAGIVRAFDKDPRDSSTPNAMAELLTKIFTGHALSPASTK +EIIGTMERCHTGNDRLRARLPATTTVADKTGTLG-GSVNDVGVITLPNGGQVVCAVFIKK +SDLPFADREKVIADIARAVYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD9173E +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTTTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. B11 TaxID=2060312 RepID=A0A2Z5YU75_9SPHN +-sALERQIASLADGSRGRIGVAAIDLATGQQV-GVLGDQRFPMASTSKIAIAATFLEGVD +QGRLSLTSEYPLLLPLSSKSSAIAPVRKGQYLQARELIQLMLTRSSNSATDALLAAVGGP +SAVNDWARRAGVKEYNLTRDIATLVRAVQIDIRDSATPRAMVQLLTGLYQGRWLRPESRD +FLIGTMEQCRTGTRRIPAQMPGDVTVAHKTGSLNN-TSSDIGILTAPDGRSIAVAIYVTG +QG-SRLNREAKIAEIARALYDGy +>[subseq from] Beta-lactamase n=1 Tax=Hymenobacter sp. TaxID=1898978 RepID=A0A519T0U2_9BACT +hqALRAEVGQLAPAASARVGVSMRVLGTGDIM-SYHNRQHYSLLSVFKLAIAMAVLHQVD +QGKLRLTQPISLTKADLPKYSPLRDKYPEGNMPVQELLRYMLVVSDNDACDILLKLVGGP +RQVTAYLRGLGIRPVVIAFSEAQMGAVWSAQYANWSYPAAQVELLDRVYRRTALSAASSH +LLYTLLRATSVTPHRLKGLLPPGTPVAHRSGTSSPNATNDVGIIELPDGRHIALAVFVSD +SYAEVAAQELLIAKIAQAVYKEf +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR480 TaxID=1500296 RepID=UPI000647776F +---LEQKINSILKNKKATVGISVLGFENSFKY-DKNADKKLPMQSVFKFHIAAAVLNAVD +QGKLSLDQKIALNKSNLLEWSPLRDQYPAGNIPLSEVIEYTVAKSDNNGCDILLRLLGGT +QPVQKFMDSKGVKGFQIKYNEEAMHKDWKVQYENYSTTQSAVDVLKKFYDGKLLSKKSTD +YLMQVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN +SMETDAVNCRMISDISKEVWEYf +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Chryseobacterium sp. ON_d1 TaxID=2583211 RepID=A0A4Y4MAJ1_9FLAO +---LEQKINSILKNKKATVGVSVLGFENGFKY-DKNGDKKLPMQSVFKFHIAAAVLNAVD +HGKLSLDQKIMLNQSNLLEWSPLRDKYPAGNIPLSEVIEYTVAKSDNNGCDILLKLLGGT +QVVQKFMDSKGVKGFQIKYNEEDMHKDWNVQYENYSTTKSASDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFISN +SMETDVVNCRMISDISREVWEYf +>[subseq from] Beta-lactamase n=1 Tax=Runella sp. YX9 TaxID=2282308 RepID=A0A369I2M6_9BACT +-dALRSNIQQIVSSKNAVVGVSIIGNNGKDTM-SLHGDRHFPMQSVFKFHIALAVLSEVD +KGKLSLDQKIEIGKDELLPWSPLRDENPNGGFTIERLIQYSVSNSDNTACDVLIRLIGTP +KTVEEYFKKNNIQDIQITYNEEEMQSKWENMFENWTTPKAASETLKMFYENNLLSKSSYD +FFWKTNIETTTGEKRIKGQLPIGTIVAHKTGWSGTAAVNNIGIVFLPNGEYFIISVFVSE +SKENFDTNEKIIADIAKATYDFy +>[subseq from] Beta-lactamase class A n=1 Tax=Dyadobacter koreensis TaxID=408657 RepID=A0A1H6YQ12_9BACT +--RVEKELERISKLAKGKVGISAVHLESGKRI-SMNLYEKYPMASTVKIAIAVQLLSKIE +KGELSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMTISDNSATDILLRLAGGQ +KAVMERLRILGIDGMSVDRTIIQLIAKLRTDPRDTSTPDAMVNLLTQIYNGKALKPESRD +LLLAVMERCKGGLARLKGYLPAETVVAHKTGSLNATATDDVGIITLPDGGHIAIAVFVAS +SAQPLAEREQTIAHLTRAVYDYf +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium glaciei TaxID=1685010 RepID=A0A172XZ44_9FLAO +---LEKKINSIIKDKKATIAVSVLGFEDDFNF-NKNGEKKLPMQSVFKFHIAAAVLDLVD +KGKLSLDQKILLDKSNLLEWSPLRDKYKDKNVPLSEIIDQTVAMSDNNGCDILLNLIGGT +QTVQKFMNSKGVKGFQIKFNEEAMHKDWQAQYENYSTTNSAVQVLKKFYDGKLLSKKSTD +YLMKVMLGTKTGLNKMVEQLPENTPVARKTGASGTGAENEIGIVTLPNGKHYVIALFVSN +STETDAINCKIISDISKTVWDHf +>[subseq from] Beta-lactamase n=1 Tax=Hyunsoonleella pacifica TaxID=1080224 RepID=A0A4Q9FUL1_9FLAO +-eTLRKKIDSIINTKSAIVGVAINGIKTNDTL-SINGQRHYPMQSVFKFPIALTILSEVD +KGNLSLDQKIEIKKNELLPWSPIRKKYPEGALTIAEIIEYTVALSDNVGCDVLLKLLGKP +QVVENYFLSLGFKDFAVKINEETMQGNWDLQFLNWTTPKEANKILITFYENKLLSKESYD +FIWNIMKGTKTGKNRLRGLLPEEIIVAHKTGSSGTAAVNNIGIVFFPNGKHLTISVFVTD +SKEDFKTNEKIISDISKVAWDYf +>[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. Root700 TaxID=1736591 RepID=A0A0Q8MFQ4_9CAUL +----------AERARPGVLGVGLMNLESGEVW-LFNGDLRFPMQSVFKAPLGAAVLAEVD +AGRLDLEQPITLTENDISPHSPIADAWPARSYTVRELLVAATGESDNTAADVLMKLIGGP +GAVTAWLDDDHVNEIRIDRYERELQPAYLADERDTATPRGVLTFFYTLDEEPILSPTSKA +LLMKIMTETPTGAQRLKAGFPAGSVFAHKTGAGRNSATNDIGVVTLPDGRRYAVASFLKG +ATLDEAGREAIHADVARAIT--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhodococcus TaxID=192944 RepID=UPI000B1FEC8C +--DVSTGLQAVEERYDVTVGVSLLNTGTGETI-SYRGAERFGFASTVKVFLAAEFLRRTP +--EDARDDLVRWTAADIERYSPVTTARLDTGLTAAELAEAAVRESDNTATNLVFDQIGGP +AELDAALSRLGDDVTDIVDVEPGLNTVGPDSTGNTTTADAFTTSLAALRGAGSSTDADAA +TLAEWMSGNATGDALVRAGAPSGWTVADKSGGAG-AVRNDIAVVTPPGRPPLVLTVLTRK +NDASAPYEDAAVSESAAVVLN-- +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter aestuarii TaxID=650004 RepID=UPI00132AA8AC +---LEQQIASLADGSNGRIGVAAVDLSTGQRI-SVLGDQPFPMASTSKIAIAATYLDMVD +QGKLSLSSEFPLMLAVRSTFSTAAAPVRQGQMPAIELIDLMITRSSNPATDALLAAVGGV +DAVNAWARRAQIEEFRLTRDIATLVRAVHIDLRDSSTPAAMVELLSGIYQGRWLTPASRS +VIIDAMERCRTGTRRIPALMPQDVTVAHKTGSLNN-TSSDIGILTAPDGRSIAVAIYVTG +QG-SRSNREARIASIARAIYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Bosea sp. UNC402CLCol TaxID=1510531 RepID=UPI00068EB1FC +--SLDKGIAKLERRTEGRLGVALIDLKDHKLW-SWRGAETFPMQSVFKLPLAVAVLQQVE +AGKFKLDQPITITRKDLSLNSPIARQFKGESYPVRDLIRLAAGQSDNTAADRLMREIGGP +QVVTKMLRDGGIENMSIDRYERQFQPAALKDKRDAATPEASARFLEGFAEGNWLRPAHTA +FLTKVISESKIGTGRIKAGLPPGSVLAHRTGLGLNHATNDIGIATLPDGRRFVIVTYLAG +SRADAPKREAALAEAARLAVS-- +>[subseq from] Beta-lactamase n=1 Tax=Flavobacterium seoulense TaxID=1492738 RepID=A0A066WVB1_9FLAO +--SLRHHIKKIAASTNAVVGVSIVGNNGVDTI-AVNAKRHFPMQSVFKFHIAVTMLSEID +KGNFSLDQKIKIQKKDLVPYSPIREKYPEGTLTIAEILKYMVSQSDNIGCDVLLRLLGGP +QFVENYFLNNKFKDISIKINEEVMQNNWDLQFQNWTTPMAANQVLASFYSQKLLSKKSHD +FIWKIMRETSTGLDQLKGKLPEGTVVAHKTGWSGTAAVNDVGVVFLPTGEHFFISIFITD +SKEDKTADAKIIAAIAKAAWDYf +>[subseq from] Class A beta-lactamase n=1 Tax=Porphyrobacter sp. IPPAS B-1204 TaxID=2483793 RepID=A0A3M9YPC7_9SPHN +--RLAAELRIIEAAGNGTLGVEIFNTATGMAV-GLNSDRRFGHASSFKLSLAALLLQRHA +AGAIDADRRVTWTQADMLEHAPFTSERMATGATLRELARATQITSDNPAANILLRQLGGP +AALTAFWRSIGDDISRVDRYEPEMNNVPTAEFRDTTTPAAMARTVAKIVYGDVLPEAERA +ELKGWMVETETGLRRVRGGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKGGPITFACYFRA +RQGMQPIGEETLARVGRVI---- +>[subseq from] class A beta-lactamase n=1 Tax=Oerskovia sp. Root22 TaxID=1736494 RepID=UPI000702200B +-hELDEALRDLERSRSLTVGVSVRG-GGRADY-GYRAAERFPMCSLFKPIAVGALLADKA +YDDAYWSREIAFGPEDLVENSPVTSATTTWRMTPAQLADAALRFSDNTAGNLVLREIGGP +TAVTSFAASLGARATRLDRIEPQLNEATPGDVRDTSTPDDVARIYGALLLERGAGALTAA +RLGDWMLRSTTSGKRFRAGLDGTYELADKTGAGGYGVVNDAGVLWRPGVEPTTLVVMTRT +DSPGATWDDEAVAAITRLVVA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium sp. 9 TaxID=2035198 RepID=A0A2G6TEH8_9FLAO +-nELRQQLNQIIASKNATVGISIKSIEDKDTL-SINGNLKAPLMSVFKFHIALAVLNLVD +EGKLSLTQEIFVKKRDLHEWSPMKEDYPDGNLTLDKILRYTVSHSDNNGCDILIDLVGGT +KVVQKFINKQGIKDFVIKVNEEQMKN-WKNLYINTTTPLAATQLLEKFYKGEILKEATTK +YLYQIMVETSRGLTWLKAGLPENTELAHRTGISGTNAMNDIGIVKLPNGKHFIISVFLKN +ITESKEDTEKIIADIARATWNYf +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=UPI0009A16929 +---LEQKINSILKNKKATVSVSVLGFENGFKY-DKNADKKLPMQSVFKFHIAAAVLNFVD +QGKLSLDQKVVLDKSNLLEWSPLRDQYPGGNIPLSEVIEYTVAKSDNNGCDILLKLLGGT +QTVQKFMDSKGVKGFQIKYNEEDMHKDWNVQYENYSTTKSAIDVLKKFYDGKLLSKKSTD +YLMKVLWSTSTGMNKIVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFVSN +STETDAVNCRMISDISREVWEYf +>[subseq from] Class A beta-lactamase n=1 Tax=Flavobacterium sp. LM4 TaxID=1938609 RepID=A0A1T1BKG5_9FLAO +-nELREKLDQIILGKNATVGISIKNIEDKDTL-SINGKLKAPLMSVFKFHIALAVLSQVD +HGKLSLDQKIFIKKKDLLPWSPIREDFPEGNLTLDKLLRYTVSHSDNNGCDILINLVGGT +KTVQKFINKQGIKDFVIKVNEEQMQS-WENLYVNTSTPLATTELLEKFYKGAVLKENTTK +YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISGTNALNDVGIVKLPNGKHFILSVYLKE +ITESKEDTEKIIADITKATWEYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella sp. enrichment culture clone MS32-6C TaxID=979976 RepID=F1CKJ6_9GAMM +----------------------------------------FAMCSTSKFMAASAILKQRE +TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP +RKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGE-------------------------- +----------------------- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. G0162 TaxID=2487063 RepID=A0A3G6S1W0_9FLAO +-nDLRSKINTIISTKNATVGVSVKGIEDQDTL-SINPNQTMPMLSVFKFHIALAVLNQVD +KGKLKLDQKFFIKKEELLPWSPIREEYPEGNLTLDQLLRYTVSHSDNNGCDILLKIVGGA +PIVQKFVNQQGIKDFTIRLNEQQMNSF-ESYFVNTSTPLATTNLLEKFYKKKILKKETTK +YLYQIMVETSRGLTWMKAGLPAGTELAHRTGISGRAAMNDVGIVKLPNGKHFILSVYLKN +INEEMKDTEKIIADIGNAVWEYy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium chungangense TaxID=554283 RepID=UPI0004DF142F +-nELREKLDQIILGKNATVGISIKNIEDKDTL-SINGKLKAPLMSVFKFHIALAVLSQVD +HGKLSLDQKIFIKKKDLLPWSPIREDFPEGNLTLNKLLRYTVSHSDNNGCDILINLVGGT +KTVQKFINKQGIKDFVIKVNEEQMQS-WENLYVNTSTPLATTELLEKFYNGAVLKENTTK +YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISGTNALNDVGIVKLPNGKHFILSVYLKE +ITESKEDTEKIIADITKATWEYf +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. JAH TaxID=1742858 RepID=A0A101CBW0_9FLAO +-sALEQKINSIIKDKKATVGISVLGIENDFKY-NKNSDKKLPMQSVFKFHIAAAVLDFVE +KRKLSLDQKIVLDKSNLLEWSPLRDKYPNGNIPLSEILELTVAKSDNNGCDIMLKLLGGP +KTVQKFMDSKGVKGFQIKYNEAEMHRNWNVQYENYSTTQSAVDVLKKFYEGKLLSRKSTD +NLMKVMLSTSTGLNKMVEQLPKSTPVARKTGASGTGAENEIAIVTLPNGKHYAIAVFVSN +SIESDAVNCKIVSDISKAVWDHf +>[subseq from] Beta-lactamase class A n=1 Tax=Bosea vestrisii TaxID=151416 RepID=A0A543NCX8_9BRAD +--SLDKGIAKLERRTEGRLGVALIDLKDHKLW-SWRGAETFPMQSVFKLPLAVAVLQQVE +AGKFKLDQPITITRKDLSLNSPIARQFKGESYPVRDLIRLAAGQSDNTAADRLMREIGGP +QVVTKMLRDGGIENMSVDRYERQFQPAALKDKRDAATPEASARFLEGFAEGNWLRPAHTA +FLTKVISESKIGTGRIKAGLPPGSVLAHRTGLGLNHATNDIGIATLPDGRRFVIVTYLAG +SRADAPKREAALAEAARLAVS-- +>[subseq from] class A extended-spectrum beta-lactamase PER-15 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI00140F0D0F +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGAP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQVAQTAYQ-- +>[subseq from] Beta-lactamase n=5 Tax=Gammaproteobacteria TaxID=1236 RepID=H6WJJ4_PSEAI +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHTDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQVAQTAYQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Bosea sp. 67-29 TaxID=1895723 RepID=A0A1Q3NQS0_9BRAD +-dKLDKGIDAIETRSKGRLGIALMDLRDRKLW-SHRGSETFPMQSVFKLPLAVAVLQQVE +AGKFKLDQPITVTRKDFSLHSPLVKAFKGERYPLSELIRLAAGESDNTAADLLMREIGGP +QVVTRMLRDGGIQGMSIDRYERQFQPKALTDKRDAATPEASAEFLEALARGNWLRPAHNA +FLMKIITETKIGADRIKAGLPAGSSLAHRTGAGLNHATNDIGIASLPDGRRFVIVTYLAG +SRADAPQREAALAEVAKLAVS-- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. StRB126 TaxID=878220 RepID=A0A077KJ89_9FLAO +-sSLEQKINSITKGKQATVGVSVLGFENNFKY-NQNGDKKLAMMSVFKFHIACAALDLVD +KGKLSLDQKVFIKKSELYNWSPFKKNHPEGNIPLSEVIDYTVALSDNNLCDILIELLGGT +QAVQKFMDSKGVKDFQIKYSERGMANGWDSLYENYTTTHSTIQLLKQFYDGKLLSEKSTD +YLMKIMLGTKTGTNKIVEQLPKGTPAAHKTGSSSTIAENDMGIITLPNGKHYAIAVYVSN +SKESEAENCKIISNISKAVWDNf +>[subseq from] Beta-lactamase n=1 Tax=Pedobacter sp. ok626 TaxID=1761882 RepID=A0A1G9P4G3_9SPHI +-sSLQQKIEGIINGKNADVGISVLFFGDRRSV-SVNGDKHYPMQSVYKFHLALAVLDQVD +KGKLSLQQNIFVKKSDLLPWSPLRDKYPNGNLPLSEIIKFTIAQSDNNGCDILFRLVGGP +NKVHKYIANLGIKDCAIVATEEEMHADDKVQFTNWTTPKAANALLLKFWNGTVLKKNTTA +FLKKTMEETVSGPNKIKGLLPAGTIVAHKTGYSGTVATNDIGVITLPNGNGMLISVFVSM +SKGNEKENDLIIAELARAAWD-- +>[subseq from] Beta-lactamase n=1 Tax=Tenacibaculum caenipelagi TaxID=1325435 RepID=A0A4R6TDT5_9FLAO +---LRKKIEKIVSDKNAVVGVSIIGNKGKDTL-SLNGDKRFPMQSVFKFHIALAVLSEVD +KGTLSLDQIVEIDKDELLPWSPLRDENPNGGFTIERLIQYNVSHSDNTACDVLIRLIGTP +KTIEEYIKKSGIEDIQITFNEEGLQARWENIFQNWTTPNAASETLKLFFENNLLSKSSYD +FFWETNKETTTGKGRIRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPDGKHFIISVFVTD +SQENFKTNERIIADMAKATYDFy +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. ERMR1:04 TaxID=1705393 RepID=A0A0N1DYR6_9FLAO +---LDKKINSIIKDKKATVAVSILGFENAFNY-NKNGEKKLPMQSVFKFHIAAAVLDFVD +KGKLSLDQKITLNKSNLLEWSPLRDKYKDTNVPLSEIIDQTVAMSDNNGCDILLQLIGGT +QTVQKFMDSKGVTGFQIKFNEEEMHKDWKVQYENYSTTNSAVQVLKKFYDGKLLSKKSTD +YLMKVMLGTQTGLNKMVEQLPKNTPVARKTGASGTGAENEIGILTLPNGKHYAIALFVSN +STETDAVNCKVISDISKTVWDHf +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Francisella TaxID=2610885 RepID=UPI0011B3A3CF +--TLDDSFKNLEDKHHGKLGIYTVNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM +QHKGFLDKQILITQDDIGTYAPVTGKNIGKTLTISQLNHAAI-LSDNPAANILVREIGGL +EKLNKLVTKLGDKDTIIKNDEPEINRTKPDNNINKTTPKAITQDIYNLAFGNILDKKHRE +IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQDKQPFALSVLYTN +PSVKAPSNEKIIQQASKLVAD-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina sp. Aq78 TaxID=1191889 RepID=UPI000D104779 +-eTLRKKIDSIINTKKAIVGVAINGIEVKDTL-SINGQRHFPMQSVFKFPIALTILSEID +KGNLSLNQKIDIKKSELLPWSPIRKKYPEGGFTIAEIIEYTVALSDNVGCDVLLKLLGEP +QAVENYFSSLGFREFAVKINEETMQNNWDSQFLNWTIPKEANKILATFYENKLLSKESYD +FIWNIMKGTKTGKNRLRGQLPKETVVAHKTGWSGTAAVNNIGIVFLPNGEYFTISVFVTE +SVEDFETNEKIISDISKAAWDYf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium viscerum TaxID=1037377 RepID=A0A316WI39_9FLAO +-kDLRNKINEIISTKKTTVGISLKGIEDKDTL-SINGNKETPMMSVFKFHIALAVLHQVD +KGKLKLDQKFFIKKEALLPWSPMRDEYPQGNLTLDQLLRFTVSHSDNNGCDILLNIIGGT +EVVQKFINQQGIKDFTIKLNEQEMSS-FDKCYINTTTPLATTELLEKFYKGKILKKETTK +YLYQVMVETSRGLTWMKAGLPIGTELAHRTGISGRAAMNDVGIIKLPNGKHVILSVYLKN +INEEMADTEKIIADISRVVWEYy +>[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter sp. GH3-15 TaxID=2545755 RepID=UPI0010F59A66 +--AAKARIIDIEKRSGGRLGVALVDPAGRFIL-SQRGDERFAMCSTFKTLLAARILSDPN +--GLQLDDRLTINPAAVEGHAPFTRSRLDEGMTVGEAAEHIVTVSDNAAANLLLDQVGGP +SGLTQWIRTLGDDVTRLDRRELELNENAAGDPRDTTAPLAFAETYRKVMHDDALGAAQRD +HLAGWLNASVTGLDRLRAGVPEGWRVGDKTWYCAAVEINDIAVFDPDGSGWYTLAFMLDR +PRETGAFVDELAAEVGAIAAE-- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. 18068 TaxID=2681414 RepID=UPI00135BDF1F +---LAQKVDSIIKDKKATVGVSVLGFEDGFKY-NKNAETKLPMLSVFKFHIAATVLDLVD +KGKLSLGQKILIKKGDLLEWSPIREKYPNGNLPLSEIINYTVAWSDNNGCDILLRLIGGA +QVVQKFMDSKGVKDFQIKHNEEQMHKGAKYLYENYTTTNSLSQLYKNFYNGKILSENSTK +FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN +STETDEVNCKMISDISKAVWDYf +>[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Sphingobacterium sp. JUb78 TaxID=2485111 RepID=A0A4R3AKM6_9SPHI +---LRKNIQQIMQNKDAVVGVAINGINHSDTL-GVNADRRLPMQSVFKFPLAIVMLTEID +KGNFKLDQKIEITKRDLTPWSPIREKYPTGTLTIKEILEYTITLSDNVGCDVLLKLLGGP +QVVESYFVKKGFKDISIKINEKTMQSNWDKQFLNWSTPKEMNRILQTYYVNNLLSMPMYD +FLWTTMKSTNTGLKQLKGQLPDQTVVAHKTGSSGTAALNDVGVVLLPSGEYFVISVFVTH +SKENQETNERIISDIAKAAWDFf +>[subseq from] Beta-lactamase n=1 Tax=Aquimonas voraii TaxID=265719 RepID=A0A1G6W4F8_9GAMM +----SLRLAQLESAHGGRLGVAVLDTGSGLGF-GWRDGERFALCSTFKLPLAALVLREHA +DGRLDGHAPIALDSQPDVPHQPAVDAARASGLSALELARAIQTTSDNLAANLLLRLFDGP +QGFTARLRALGETDLRVDRWEPEMNEVPTGEQRDTVSPRGMARLCARLFGPGLLDASSQR +VLAHWMIETRTGLKRLRAGLPPDWRIGDKTGTAGANKHNDVAIAWPPRRPPTLIAAYYEA +DAHMRPQDDAVLAEVGRIVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI0011F3F563 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNAERDTTMPAAMATTLRNLVTRALLTLAA-- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=8 Tax=root TaxID=1 RepID=A0A127SH14_9BACT +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNADIIARISRMVYDA- +>[subseq from] class A beta-lactamase n=1 Tax=Porphyrobacter sp. SLTP TaxID=2683266 RepID=UPI0014124805 +--RLAAELRLIEAVGNGTLGVELFDTVSGMSV-GLNRDRRFGHASSFKLSLAALLLQRHA +AGAIDADKRVTWTEADMLEYAPFTRERIATGATLRELARATQVTSDNPAANILLRNLGGP +AGLTAFWRSIGDEVSRLDRYEPEMNIVPPAEFRDTATPAAMARNVAKIIYGDVLPDAERA +ELKGWMIATETGLRRVRAGLPEGWVAGDKTGTSGEGNYIDIGFAEGPKGPPITFACYFRA +RQGDAARAELTLSRVGRII---- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium nakagawai TaxID=1241982 RepID=A0A3N2F8T4_9FLAO +-qDLRNKIKTIISTKNATVGISVKGIEDHDTL-SINGNKEMPMLSVFKFHIALAVLNQVD +KGKLKLDQKFFIKKEDLLPWSPIREEYKEGDLTLDQLLRYTVSHSDNNGCDILLKIIGGA +PVVQKFINQQGIKDFTVKLNEQQMNTF-ESYFINTSTPLATTDLLEKFYKGKVLKKETTK +YLYQIMVETSRGLTWMKAGLPIGTELAHRTGISGRAAMNDVGIAKLPNGKHFILSVYLKN +INEEMKDTEKIIADIGSAVWEYy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium piscis TaxID=1114874 RepID=UPI00080B5277 +-nELRQQLSQIISSKNATVGLSIKGIEDKDTL-SINGNLKVPMMSVFKFHIALTVLDKVD +QGKLSLTQEIFIKKKDLHEWSPMREDYPDGNLTLDKVLRYTISHSDNNGCDILIDLLGGT +KEVQKFINKQGIKDFVIKVNEQQMRT-WENLYVNTTTPLATTVLLEKFFKGQILKESTTK +YLYQIMVETSRGLTWMKAGLPKNTELAHRTGISGTNAMNDIGIVKLPNGKHFILSVYLKN +ITEKQEDTEKLIADITKVTWDYf +>[subseq from] Beta-lactamase n=1 Tax=Oxalobacteraceae bacterium TaxID=1871070 RepID=A0A4Q3IBF9_9BURK +--SVSAELQEIEKFAGGQLGVFARQTEPERSL-ALGADVRFLMCSTFKLLAAAGTLDRID +NHHELATRRLSYSASDLVEPHPVTGSNVQAGLPLWTLCEAAVAQSDSTAANLLMRAAGGP +AGLTGFIRSIGDGVTRIDRYELAANTA--SGDLDTTTPKAVVRSVHKLLLTDRLSLKSRQ +ALEEWMRADQRGLRRLRAGFPPSWMAGSKPGTSPV-VVNDVAVLRPPSGTPVIVGAFYRS +EPAPLEKREAVLASVGRVVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4V1CBM7_ECOLX +-------------------------------------------CSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDATFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSG--------------------------- +----------------------- +>[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Sunxiuqinia elliptica TaxID=655355 RepID=A0A1I2JJ26_9BACT +---LRDEINQILKDKSATVAVAIEGTAMHDTL-SINADRHMPMQSVFKFHLALAVLEQID +QGKFSLDHQLSFDKNKVDRYSPLREKYPQGAVSVAELLKYTVSLSDNLGCDLLFQLVGGP +EVVQSYLHQIGIKDIAIVYNELLMQSDWSHQYQNWTTAHATNQLLQLFFESQLLSTENHQ +FLLDILKGTTTGKKSIRGLLPKDAVVAHKTGHSGTGALNDIGIVFLPNGSYFYLSILVSD +SMEDNKTNQQLIAQISKLAWDYf +>[subseq from] Beta-lactamase n=1 Tax=Microscillaceae bacterium TaxID=2053581 RepID=A0A3C0I8L5_9BACT +-eTLRSALQQIVADKNATVGVAIRSSNGSDTV-SLNGTQHFAMQSVFKFHIALAVLSQID +QGKFSLSQAIEVKPQELLPWSPLREANPQGGFPISVLLSYAVSVSDNVACDVLLRLLGGP +TVVETYFKQNNIQDISIQINEEIMQANWDLMFQNWTTPQAANEVLVKFYENSLLSAESYA +FVWKVMKETSTGLKRLKGQLPEGTVVAHKTGTSGTEAVNDIGVIFLPNGDYFFISVFVTH +SKEDEATNEKIVADIAKAAWDYf +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. KBW03 TaxID=2153362 RepID=A0A3N7AIL2_9FLAO +---LEQKINSILKNKKATVGVSVLGFENGFKY-DKNADKKLPMQSVFKFHIAAAVLNAVD +QGKLSLDQKIVLNKSNLLEWSPLRDKYPEGSIPLSEVIEYTVAKSDNNGCDILLKLLGGT +QTVQKFMDSKGVKGFQIKYNEEAMHKDWNIQYENYSTTKSAVDVLKKFYDRKLLSKKSTD +YLMKVMWSTSTGLNKVVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALTVFVSN +SMETDAANCRMISDISKEVWEYf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium CCH10-E5 TaxID=1768797 RepID=UPI000837875E +--RLSREIVAIERDAKGRLGVALLDLKDRSLW-SHRGSERFPMQSVFKWPLAIAALQAVE +AGKLRLDQPVTIKRSEFSLHSPLAKAFKGEAYPVRELIALAAGESDNTAADILMREIGGP +QAVTAMLRAGGITGISVDRYERQFQPAALKDPRDSATPEASVAFVEAQAKGNWLREPAHS +ALIDITLETKSGPDRIRAGLPQGARFAHKTGAGLNHATNDIGLVTLPNGRVFAIAVYLAG +STADAKAREAAHAAVARLAVS-- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium haifense TaxID=421525 RepID=A0A3G6SZ42_9FLAO +-aELKKEISKITEGKKATVAVSVLGIDFPFQYnNENAEKKLPMQSVFKFHIALAVLDLVD +QGKLSLDQKVFIKKSELLPWSPIREKYTEGNLPLSEIIEYTVAMSDNIGCDVLLRLIGGP +TVVNDFIISKGVKDTQIIYNEELMQTAWRNQYENYTTTKSATKLLKDFYNGKVLSKKSTE +FLLGVMYRTSTGLNKIVEQLPKSAKVAHKTGSSGRNAENDIAIITLPNGKSYAIAVFLSD +STESYDVTCKLISDISEVVFENf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. AF25-17LB TaxID=2292922 RepID=A0A3A5YJU1_9BACE +-sELENQIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD +SYETDEDNADIIARISRMVYDA- +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium culicis TaxID=680127 RepID=A0A2S9CZK7_9FLAO +---LEQKINSILKNKKATVGVSVLGFENGFKY-DKNADKKLPMQSVFKFHIAAAVLNFVD +QGKLSLGQKVLLDKSNLLEWSPLRDQYPGGNIPLSEVIEYTVARSDNNGCDILLKLLGGT +QTVQKFMDSKGIKGFQIKYNEEAMHKDWNVQYENYSTTKSAVDALKKLYDGKLLSKKSTD +YLMKVMWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN +SMETDAVNCRMISDISREVWEYf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides uniformis dnLKV2 TaxID=1235787 RepID=R9HTF7_BACUN +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGTLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNADIIARISRMVYDA- +>[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium sp. ov086 TaxID=1761785 RepID=A0A238ZCY2_9FLAO +-nELRQQLNQIISSKNATVGVSIKGIEDKDTL-SINGNLKAPLMSVFKFHIALTVLNKVD +EGKLSLTQEIFIKKKDLHEWSPMEKDYPEGNLTLDKLLRYTVSHSDNNGCDILIDLVGGT +KEVQKFINKQGIKDFVIKVNEEQMKN-WKNLYVNTTTPLAATALLEKFYKGEILKESTTK +YLYQIMVETSRGLTWMKAGLPENTELAHRTGISGTNAMNDIGIVKLPNGKHFIISVFLKN +ITETQEDTEKIIADITRTTWNYf +>[subseq from] Class A beta-lactamase n=1 Tax=Dyadobacter sp. AR-3-6 TaxID=2541721 RepID=A0A4R5DC11_9BACT +--RLQNELERIAKLAKGRVGVCARHLESGKQI-SLNLNEAYAMASTVKVAIAVQLFNKIE +KGEISLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLAGGP +KAVDQKIKDLGIQGMSVDRTIVELIAKLRKDPRDTATPLAMVNLLTGIYQNTVLKPESRD +NLLAVMERCRGGAARLKGYLPPSTLVAHKTGSLNATATDDVGIITLPDGGHIAIAIFVAD +SEQPIEQREQTIAHLTRSIYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A3B8LZP9_9PLAN +--RLAARIKPLVSRHKGQVSVLVKHLGSGRSF-AWKPDRPMPTASLIKLAVMVEVYRQVE +KGRVDLDDRLKLDEDDKVPGSGLLRKYFTAGLTLRDAVRLMIAVSDNTATNLVLDHI-GL +ESTNRTMSRLGHLNTRIHAKVFRRETSIDPDRSGSTTASETVSLLEAIHRGKLVSESASQ +QMLEHLKACES-TERIPRFLPSGTVVAHKTGSVSQ-VRTDAGIIDSPAGG-IAICVLTSK +NAGPANAASRLIADISREAFLHf +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8MCU2_9BACT +--TLRTQIERVIPRARGQVGVAIKHVESGTEL-MVNADQTYPMASTYKVPILVELFYQRA +AGKLSLSDRIEVDPSDVHPGGTIALLLDGPGMSIHNLINLMMRVSDNSAADILLNRI-GP +ANVTARMRSLGLDKIRVDRSTLEMILRFNTTEKDVATPRQMTLLLERIYRGEIVDRASSD +EMMEFMNHSMIGQTRIPALLPEGTRVVHKTGTIS-GSTNDTGVVFLPGGGHLLMTVFTKD +AKAPAADREHVVAEIARFAYDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium tiangeerense TaxID=459471 RepID=UPI00119D33E2 +-nELREELNKIISTKNATIGVSIKSIEDKDTL-SINGKLNAPLMSVFKFHIALATLNLVD +KEKLTLTQKIFIKKQDLHKWSPIRDEFPEGNLTVDQLLKYTVSHSDNNGCDILLDLIGGT +EAVQKFINNQGIKDFTIKVNEQEMQTR-ENLYINTTTPLATTELLEKFYKGKILKKKSTN +YLHQIMVECSRGSTWMKAGLPDGTELAHRTGISGTNALNDVGIVKLPNGKHLIISVYLKN +ITETKENTEKIIADITKATWHHy +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D4E6507 +------------------------------------------------------------ +-----------------------TKKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RAU3_9BACT +------------------------------------------------------------ +------------------------------------------------------EQLGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD7CE04 +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPVADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTTTFPDRLRSGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Adhaeribacter aquaticus TaxID=299567 RepID=UPI00041376C5 +--SLPEKIQQIISAKNATVGVSIIGRNGKDTL-SINGERHFPMQSVFKFHIALAVLSQVD +KGTLSLDQKIKIKRKDLLPHSPLRDKYPNGALPLAEILSYTVSNSDNVGCDALLRLLGGP +QAVEKYFMENNFKAISIKINEEVMQHNWDLQFQNWTTPNAASNVLEAYYHNKLLSPKGYD +FVWKEMRENESGKNRLKGRLPEGTVVAHKTGSSGTAAVNDIGIVFLPNGEYYFISVFVSN +SKEDFNTNEKIIADISKAAWNY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Riemerella anatipestifer TaxID=34085 RepID=UPI00077B81C3 +---LDKKINSIIKDKKATVGISVLGFENNFQY-HKNGKKKLPMLSVFKFHIAATVLDWVD +KGKLSLEQKIFIKKEDLLKWSPIRDQYPDGNMSLDEIIRYTVAWSDNNGCDILLKLIGGT +ETIQKFINSKGIKNFQIKNNEEQMHKASKYVYENYTTTQSLALLYKQFFQGKIISEKSTH +YLYNIMLNTETGKNKLKEQLPPK-TVAHKTGSSGYEAENDSGIVTLPNGKHYSIVVFVNN +STEPEAVNCKMISDISKTVWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium naphthalenivorans TaxID=273168 RepID=UPI000A051CBE +---LGQRLASVAEASQGRIGVAALDLATGREV-DVLGDQRFPMASTSKVAIAATFLEGVD +QGKWSLTSEFPMMIPVQSASTAVAPVRPGAYMSAGKLLELMLTRSNNYATDALLKVVGGP +DAVNAWVRRAGIEDWHIDRDIATLVRAKVVDKRDSATPLAMVKLLSGIYQGKWLSPSSRQ +TLLDTMSRCLTGKRRIRAGLPEDVQVLHKTGSLHN-TSSDIGIIEAPDGRVFAVAIYVTG +QG-SRPNREARIASIARTIYSGy +>[subseq from] class A beta-lactamase n=1 Tax=Type-F symbiont of Plautia stali TaxID=1560358 RepID=UPI0009E7A47E +------------------------------------------------------------ +----------------MVNYNPVTMKHIGSAMSLAELSAAALQYSDNAAMNKLLAYLGGP +QHATQFARTLGDTTFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNKLVLGSALKDDQKA +TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNYAPLVLTTYFTQ +HDKSAAARKDVLASAARVIAD-- +>[subseq from] BlaGES-5 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A2S1JL16_PSEAI +---FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH +TIERWLIGNQTGDATLRAGFPKDWGCWRENWYLRQRGPERHWFFKAQER-DYAVAVYTTA +PKLSAVERDELVASVGQVITQ-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Tenacibaculum agarivorans TaxID=1908389 RepID=UPI00094BAEB9 +-eSLREKIEKLINTKKATVGIAINGIEAKDTL-SVNGGKHFPMQSVFKFPIALTILSEID +KGNLSFDQKINIKKSELLPWSPIRKKYPEGCLTIAEIIEYTVALSDNVGCDVLLKLLGKP +QAVESYFSNLGFKDFAVKINEETMQNNWELQFLNWTTPKEANRILTTFYENKLLSKRSYD +FIWNVMKETQTGKNRLKGQLPKGTVVAHKTGWSGTAAVNNIGIVFLPNGKYFTISAFVTE +SKEDFKVNEKIISDIAKVAWDYf +>[subseq from] Beta-lactamase n=1 Tax=Francisella sp. TX07-6608 TaxID=573568 RepID=A0A1S2WU14_9GAMM +---LNDSFKSLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM +HNQGFLDKKIPITQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDNPAANILVRELGGL +QNLNKFIKKLGDNDTIITADEPEINYTQPHSNINKTTPKAITKDIYKLAFGNILDKKHKD +IFIKYLQDNNTGANRIAFGMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN +PNKNTPSNEEIIQQAAKLIAN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SUD9_9BACT +-sELENRIDSLLNGKNATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMAQLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD +SYETDEDNADIIARISRMVYDA- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. IHB B 17019 TaxID=1721091 RepID=UPI000720182A +---LEQKINSIIKDKKATVGVSVLGFENGFKY-NKNSEKKLLMQSVFKFHIATAVLDFVD +KGKLSLDQKILLNKSNLLEWSPLRDKYPNGNVPLSEILEYTVTKSDNNGCDIMLKLLGGT +KTVQKFMDSKGVKGFQIKYNEEAMHKDWNAQYENYSTMRSTVDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGLNKLVEQLPKNTPVARKTGASGTGAENEIAIITLPNGKHYAISVFVSN +SMESDAVNCKMISDISKTVWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000489F1B0 +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTTTFPDRLRSGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. RU37D TaxID=1907397 RepID=A0A1N6TD26_9FLAO +---LSQKINSIIKNKKATVGVSVLGFENGFKY-NKNGEKKLPMQSVFKFYIAATVLDLVD +KGKLSLDQKILLNQSNLLEWSPLRDKYPNGGVPLSEILEMTVAKSDNNGCDILLKLIGGT +QTVQSNMNSKGVTDFQIKYNEAEMHKDWKAQYENYSTTNSAVQVLKKFYDRKLLSKKSTD +YLMKIMLSTSTSLNKIVEQLPKNTLVARKTGASGTGAENEIAIITLPNGKHYAIAVFVSD +SMESDAVNCKVISDISKTVWDYf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium jejuense TaxID=445960 RepID=A0A2X2VLP6_9FLAO +----EQKINSITKGKQATVGVSVLGFENNFKY-SQNGDKKLAMMSVFKFHIACAALDLVD +KGKLSLDQKVFIKKSELYNWSPFKKKYPEGNIPLSEVIDYTVALSDNNLCDILIELVGGT +QAVQKFMNSKGIKDFQIKHSERGMASGWDSLYENYTTTHSTVQLLKQFYDGKLLSKKSTD +YLMKTMLGTKTGTNKIIEQLPKGTPAAHKTGSSGTIAENDMGIITLPNGKHYAIAVYVSN +SKESEAENCKIISNISKAVWDNf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus stepanovicii TaxID=643214 RepID=A0A411KFA0_9STAP +-nSTNNDIEKIEKKYGANVGMYALNTQNGKEL-SFNENKRFAYASTLKTISSAMLLEQTP +--YNKLDKKIHINKDDIVPYSPVLEKYIGKKITLKKLIEATMLVSDNTANNKIIDELGGY +EQVKTRLIDLGDSTTHPSRKEPNLNYYSPKDKRDTSTPLAYGKTLKKLISDGNLSKANKD +FLLDLMFKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVAFVYPDGQKPIILVIFTNK +DR--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacterales bacterium 32-67-6 TaxID=1970502 RepID=A0A258CII2_9PROT +-------------------------------W-AINGSDRFPMQSVFKAPLGAAVLAEVD +AGRLSLSDTITGSDEDLSPFSPVAAAYPGRRYRVDELLTLAVGASDNTAADLLMGRIGGP +GAVTAWLRSHGIEHMRVDRYERQLQPRYLTDPRDSTTPRDALLFLAMLARGELLSEASTR +HLLKIMEETPTGADRLAAGLPDGARLAHKTGTARTDATNDIGLITLADGRRYAVAVFLSG +STQSEAEREAIIADVARAVTQ-- +>[subseq from] Serine hydrolase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=A0A2J0YYU1_RHIML +--RLRLELETLADAHPGRVGICVQD-QPKSPV-CVNGAQRFSLQSVMKLVVAAAVMQAVD +EQRIRLDDQITIRREDLSVIQPIADIVARHGTSVRDLVRRAVVASDSAATDVLIARLGGP +KAIQAFLEKAGLTGVRIDRTERELQTAYIKDPRDTATPRGMAAFLYSLASGSLLTAGSTE +FLLTVMSQTTTFPDRLRAGIPPEWGIGHKTGTSQNGVTNDVGILTAPDGRRIAVAAFVAE +SRAGQAERAAVIAAAARAITAAy +>[subseq from] Beta-lactamase class A n=1 Tax=Agromyces cerinus subsp. cerinus TaxID=232089 RepID=A0A1N6E7E9_9MICO +hrRLTEAIAELERATSVTIGVTALWHDSRRAF-RYRGDELFPMCSVFKTLAAGALVQARG +YDDVYWAKPIPFTLADVVGKDTRLN--RDTWATPEEMADAAIRYSDNTAGNLLLRELGGP +QAVTAFARSLGANRTRLDRPEPQVNEATPGDERDTSTPDDIAFLLQLLLIDQGAGALTTA +RLQEWMLRNTTSGKRILAGLTPPFELADKTGLGGYGVVNDAGVIWRPGEEALTLAILTRT +DRADAPSNHDVLADVTRLIVA-- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium cucumeris TaxID=1813611 RepID=UPI000F459A78 +---LEQKINSILKNKKATVGVSVLGFENGFTY-NKNANKKLPMQSVFKFHIAATVLNAID +QGKLSLDQKIKLDQSNLLEWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLRLLGGT +RTVQKFIDSKGVQGFQIKYNEEDMHKDWNVQYENYSTTKSAVDILKKFYDGKILSKKSTD +YLMKVLWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFVSN +STETDAVNCRMISDISREVWEYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina megaterium TaxID=1443666 RepID=UPI0004724BEC +---LRKTIEQIVSDKNAVVGVSIIGNNGTDTL-SLNGDKRFPMQSVFKFHIALAVLAEVD +KGILSLDQTVVIGKDELLPWSPLRDENPNGGFTIKRLIQYNVSHSDNTACDILIRLIGTP +KTVEEYIKKSGIEDIQITFNEEGLQAKWENIFQNWTTPNAASETLKLFFENNLLSKSSYD +FFWETNIDTKTGKNRIRGQLPKEIIVANKTGWSGTAAVNDIGIVFLPNGNYFVVSVFVTD +SQEDFKTNAKIIADIAKATYDFy +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter lutipelagi TaxID=1964208 RepID=UPI0010F56315 +--RLNSRLRLIEASANGSLGASIYDPGTGTHV-SHNGFARFPHCSSFKLSLAALVLKSGH +DGVLDIDERIGWDKDALLGHSPFTTERLSEGATLMELAAATQIVSDNTAANLLLSRVGGP +EGLTAFWRAIGDEKSRLDRYEPDLNHVPIGELFDTTTPDAMSRTVSRLLREDVIDSGSRS +NLRGWMIDTRTGLDRVRAGLPEGWIAGDKTGTSLRSVYVDIGFVEPPVRGPLTYAVYFRA +NEKAQPAALAVFAEVGRVIT--- +>[subseq from] Class A extended-spectrum beta-lactamase VEB-24 n=1 Tax=Providencia rettgeri TaxID=587 RepID=A0A650A8F6_PRORE +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHYPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSETDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGTAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWDYy +>[subseq from] Uncharacterized protein n=1 Tax=Bosea vaviloviae TaxID=1526658 RepID=A0A1D7TVR3_9BRAD +--RLDQEVAAIERQSQGRLGVALLDLKDRKSW-SHRGSETFPMQSVFKLPLAVAVLQAVE +AGKLKLDQPITITRKDFSLHSPLAKAFKGESYPLRELIALAAGQSDNTAADNLMRLIGGP +QVVTKMLRDGGIGGISVDRYEREFQPLALKDPRDAATPEASTLFLEALAKGNWLRDPAHA +AFLDMVIETTSGPLRIRAGLPLGARFAHKTGAGLNHATNDIGIVTLPNGRVFAIAIYLAG +SKADEKTREAAHAAVAKAAVA-- +>[subseq from] Beta-lactamase n=4 Tax=Bacteria TaxID=2 RepID=A0A127SZJ8_9BACT +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMAQLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD +SYETDEDNADIIARISRMVYDA- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SH64_9BACT +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMAQLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD +SYETDEDNADIIARISRMVYDA- +>[subseq from] Beta-lactamase class A n=1 Tax=Bosea thiooxidans TaxID=53254 RepID=A0A0Q3I7K0_9BRAD +------DLRSLEERHGGRLGLFATR--ESQRV-GWRSTERFAFCSTFKLFLAAYVMQTVQ +QGRDRLDRAVPITAADMVPHGPVTQPAIGRTLTLEELCKAAVEVSDNPAANILIREMGGL +AAFQLWYRSIGDQVTSVDRMEIELNSALPGDMRDTTTAEQYVANLDRVVRGNLLSAAHLQ +LLVRWITETPTGAGRIKAGVPAGYTVGHKTGTGARSTHNNIGIMS--------------- +----------------------- +>[subseq from] Beta-lactamase class A n=2 Tax=Mucilaginibacter sp. YR332 TaxID=1855298 RepID=A0A497Z3S8_9SPHI +--KLRTQIVEIAKDAKGTVGVSILNLETRDTL-SLNGHAHLPMQSVMKFSIAITVLHEID +KGHFKLDQLIHIGKSDYYDYSPLKDKNPVADISIRELLSYMVSLSDNVACDVLIKTLGGI +NKVNDYIHSLGVKNIAFKATEFQMAQAWPVQYTNWAQVTDLTHLLDISFNPNFLSAASHA +YLWKIMQETSTGPNQIKGLLPAGTIVYHKTGRSGTAATNDIGIITLPNGKHLAIAIFVSD +TSVDLQMRESVIARIAKAAFD-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Runella zeae TaxID=94255 RepID=UPI000490391B +-sDLRQKINKILATKNAVVGVAISGNNGKDTL-SINANRHYPLQSVFKLHIGLVVLSQVD +KGKLSLDQKIEIQKKDLLPYSPIRDKYPNGALSIAEILESTVASSDNVGCEVLLRLLGGP +KVVEDYFIQHNFKDISIKFNEEQQQGNWELQFQNWTTPKAANEVLAAFYYKKFLSAKSHD +FIWRVMRETTTGAKRLKGALPPNTVVAHKTGSSGTAAVNDIGIVFLPNGHHFFISVFVTD +SKENAETNEKIVADIAKVAWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter sp. ZODW24 TaxID=2185142 RepID=UPI000DF7AF59 +---LEKQIAMLANGDNGRIGVAAVDLATGREI-AILGDQRFPMASTSKIAIAATFLEGVD +KGRWSLDDRYPLLHPIRSAYSSRAAPVKRGQYTARELIESMITRSSNSATDAMLAAVGGT +GKVNAWLRRSGIKEVRIDRDIATLVRATFIDERDSATPRAMVELLSGLYQGKWLSASSRR +VVIGAMERCRTGKRRIPKLLPANALVAHKTGSLNN-TSSDIGVITAPDGRSIAVAIYVTG +QG-TRSRREAKIASIASAIYEGy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SW64_9BACT +-sELENRIDSLLSGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD +SYETDEDNADIIARISRMVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Aminicenantes bacterium RBG_19FT_COMBO_58_17 TaxID=1797275 RepID=A0A1F5C174_9BACT +--RLRRRVEDVIKRAEGEVGVALRHLESGQSL-EINAGSRFPMASTFKLPVLVEIMAQVK +EGKLSLEDEVSVQKTEQHLGSGMLSSLTAPGLTVRNLANLMMMISDNSAADILLAKA-GP +ENVNKRLRQYGVEGISVNRSCQELIMKFILDPRDQSTPAAMNRLLEKVYKKEILDPESCD +LILSIMLQCQTGEGRIKGKLPPGAPVAHKTGTIA-GTVNDTGIITLPDGGHMAITVFTKG +FEDETEDVEKIIAEIARLVYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Rubrivirga marina TaxID=1196024 RepID=UPI000BA9323E +--ALADEVERLAAPAEGRVGVGIALLGSDEAV--VVGEGRHPMQSVFKLPLGMAVLAAVD +RGELSLDRRVAVTLADFVSHSPIRDRHPDGVLSVGELLGAAAGGSDGTAADVLLDLLGGP +AEVEGFLRGIGVEGVDVAVTEKDMGRDYDAQYRNGATPAGALALLRALHAGRGLSQESRT +LLLRVLTETTTGPNRLRGRLPEGTPVAHKTGTSRTAATNDVGLVTLPDGRRLAVAVFVSD +SPADDATRERVIADVARAAYDAw +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Candidatus Chryseobacterium massiliae TaxID=204089 RepID=A0A3D9AP70_9FLAO +---LEQKINSITKDKKAMVAVSIHSFEDNIKL-SINGNKKLPLLSVFKFHIALTVLNLVD +QKKLNLKQKILITKADLHEWSPFRNKYPNGNMTIEELLQYMISQSDNNITDVLIHLVGGT +QSVQKFMDDLTVKDFTIKADESKMHEGFEFHYWNTSTTNSLNQLLKRFYDKKIISKTSTS +FLMKTMIQTTTGSNKIVALLPKDTPVAHRTGSSGKNAENDIGIITLPNGRHIALSILVSD +SMESEETNTKMVAEIAKVVYENf +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00050A362A +------------------------------------------------------------ +------------------------EKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Francisella persica ATCC VR-331 TaxID=1086726 RepID=A0A0K2JRB7_9GAMM +--QVTNDIQNIEKKYGGKIGVYTINRNDWSNF-TVNASFYFPICSTYKFLVVGAILKQSM +DDNKLLNQNLKISKNKIVGYSPITRKYINQTMTIKQLCKASMQ-GDSAATNILIEKLGGL +KNLNKFILSLADHATKITNLEPKVNSVSLITNKNKTTPKIIARDINKLAFSDALDKKHRL +MFKKWLIASSTGNNLITAEVPDEWEVGDKTGTCQYGTTNDVAIIWPNDNRAIIMAIFYTQ +SQKNAKPNSKIIREVTKILLD-- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A519LIB3_9FLAO +---LDQKINSIVKDKKANVGISVLGFENNFKY-DKDADKKLPMQSVFKFHIAAAVLDFVE +KGKLSLDQKIILNQSNLLAWSPLRDKYPDGNVPLSEILEFTVAKSDNNGCDILLKLLGGT +QTVQKFMDSKGVKSFQIKNNEAEMHKNWNLQYDNYSTTQSAVDVLKKFYDGKLLSKKSTN +YLMKVMLSTSTGLNKLIEQLPKNTPVARKTGASGTGAENEIAIITLPNGKHYAIAVFVSN +STESDATNCKMISDISKAVWDDf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SUC6_9BACT +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD +SYETDEDNADIIARISRMVYD-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Acinetobacter baumannii TaxID=470 RepID=E5KCK4_ACIBA +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQVLRL----- +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga barathri TaxID=1647451 RepID=A0A3N4M6P0_9BACT +--SLRKTIDSIVTQTDGKVGVAILHLGSRDTL-TLNDTAHFPMQSTFKFPIAMAVLKQVD +EGKLKLDQEVPIGKNWMATHSPLRDSLAKVKPTIATMLSYMVSLSDNVACDVLLELIGGE +PVANDFIHGLGVNNIAIVASEIKMGKAWDVQFTNWCQPSAYTQLLDILDKGTALSKASND +FLLKIMFETTTGPGRIRGLLPKELQVAHKTGTSGAAATNDVGIIVLPSGQKLAIAVFVSL +SHADEATREKVIAQITKAAYDH- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=unclassified Flavobacterium TaxID=196869 RepID=UPI000D9B2697 +-nELRQQLNQIISSKNATVGISIKGIEDKDTL-SINGNLKAPLMSVFKFHIALTVLNKVD +EGKLSLTQEIFIKKKDLHEWSPMEKDYPEGNLTLDKLLRYTVSHSDNNGCDILIDLVGGT +KEVQKFINKQGIKDFVIKVNEEQMKN-WKNLYVNTTTPLAATALLEKFYKGEVLKESTTK +YLYQIMVETSRGLTWMKAGLPENTELAHRTGISGTNAMNDIGIVKLPNGKHFIISVFLKN +ITETQEDTEKIIADITRTTWNYf +>[subseq from] Class A beta-lactamase n=1 Tax=Erythrobacter sp. YH-07 TaxID=2182384 RepID=A0A345YCK8_9SPHN +----SATFRILERALGGRLGVAFHAPARHAHI-AYRGDERFPMCSTFKTSLAAQALSLGQ +DGTLDLSERVTWTADDLIFHTPFTGERVAQGATLSELAHAAQTVSDNLAANLLLDRVGGP +AGLTAFWRRLGDETSRLDRMETAVNFVPEGDVRDTTTPVAMARTLAKMLATNPLAAPRRR +ELRQWMIESTTGLKRVRAGLPEDWVAGDKTGNSGY-LRGNIGFALDPSEAPTFFAVYHQS +PVIDGQRVDAAFAQVGRLLA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=A0A411KFJ0_STAXY +--STNNDIEKLEKKYGANIGMYALNTQNSEAL-SFNENKRFAYASTLKAISSAMLLEQTP +--YNKLDKKIHINKDDIVPYSPVLEKYIGKEITIKKLIEATMLFSDNTANNKIIDELGGY +EHVKNRLTDLGDTTTHPSRKEPDLNFYSPKDKRDTTTPMAYGKTLNKLIVDGNLSKANKD +LLLDLMLKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVALVYPDGQKPIILVIFTNK +DK--------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T1C3_9BACT +-sELENRIDSLLNGNKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMAQLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD +SYETDEDNADIIARISRMVYDA- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B2CD69_KLEOX +--------------------------------------RSFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVQD----------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina sp. AU474 TaxID=2108529 RepID=UPI000D69F057 +-eTLRQKIDSILNTKKTIVGVAINGMKVNDTL-SINGQRHFPMQSVFKFPIALTILSEVD +NGNLSLDQKIDIKQSELLPWSPIRKKYPKGVLTIAEIIEYTVALSDNVGCDVLLKLLGKP +QAIENYFSSLGFKDFAVKINEETMQNNWDLQFLNWITPIEANKILATFYENKLLSQESYD +FIWNIMKGTKTGKNRLRGQLPEETIVAHKTGWSGTAAVNDIGIVFLPNGEHLTISVFVTE +SKEDFKTNEKIISDISKMTWDYf +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Flavobacterium sp. B17 TaxID=95618 RepID=UPI000344BA4E +--ALGQKINSIIKDKNATVGISVLGFEDGFTY-KRNADKKLPMQSVFKFHIAATILDYVD +KVKLSLDQKVLLDKTNLLEWSPLRDKYPNGGIPLGEVLEYTVAKSDNNGCDILLKLLGGT +QTVQRFMDSKGIKGFQIKYNEAEMHKDWNIQYKNYSTAASATDVLKKFYDRKLISKNSTD +YLMKIMFSTSTGKNKLIAQLPENTPVARKTGASGTGAENEIGIVTLPNGKHYAIAVFVSN +STETDVVNCKMISDISKSVWDYf +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium balustinum TaxID=246 RepID=A0A3G6TQ56_9FLAO +---LAQKVDSIIKDKKATVGVSVLGFEDDFKY-NKNATTKLPMLSVFKFHIAATVLDLVD +KGKLSLGQKILIKKGDLLEWSPIREKYPNGNLPLSEIINYTVAWSDNNGCDILLRLIGGA +QVVQKFMDSKGVKDFQIKHNEEQMHKEAKYLYENYTTTNSLSQLYKKFYDGKILSEKSTK +FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAVVVFISN +STETDEVNCKMISDISKAVWDYf +>[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter neustonensis TaxID=1112 RepID=A0A192D3X4_9SPHN +---LAAELRIIEAAGNGTLGVEIFNTATGGSV-GINQDKRFGLSSTFKLSLAALLLQRHA +AATIDADRRVTWSEADLVFHAPFTRDRIASGATLRELARAAQLTSDNPAANILLRNLGGP +AGMTAFWRSLGDDVSRLDRYETQLNDVPTPEFRDTTTPAAMARTVARIIYGDVLPETERA +ELKGWMVETDTGLKRVRAGLPEGWIAGDKTGTSGY-IYSDIGFAEGPKGGPLTFACYFRA +RQTELARGEQALARVGRII---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KI40_9BACT +-------FQELDEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS +--IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFTLLDGP +NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLAFNLKEYVTGDILSDDKKE +IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRN--------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RFP5_9BACT +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMATTLRKLLTSP-------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. CF614 TaxID=1884364 RepID=A0A1I2LLK1_9SPHN +---FEQQLAAVAEASRGRIGVAAVDLASGRMI-DVLGDQRFPMASTSKVAIAAAFLEGVD +QGKWSLTSEFPLMIPVGSAYSSAVAPRAGEYMTAERLIELMITRSNNYATDALLKVVGGP +SAVNAWVRRAGIENWHMDRDIATLVRAVVIDKRDSATPVAMVQLLAGVYQGKWLSPQSRA +VLLGAMSRCVTGKHRIAAGMPEGVSVSHKTGSLNN-TSSDIGIVQTPDGRVFAVAIYVTG +QG-SRPGREARIASIARTVYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Francisella philomiragia TaxID=28110 RepID=UPI0005A571A6 +--EISNRLHNLEKLYGGKIGVYTINRNNNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM +TDNNLLDKEVKISANQIIGYSPVTKKHINQTMTVSELSKAAI-QSDNTATNLLIEKLGGL +NNLNNFILSLHDHATKVAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILDKKHRL +LFKKWLLENDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMAIFYTQ +SQKDAKPNSKIIREVTKILLD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A4Y1PU18_KLEPN +-----------------------MDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASRAATLRKLLTSQRLSARSQR +QLLQWMV----------------------------------------------------- +----------------------- +>[subseq from] CblA family class A beta-lactamase n=1 Tax=Bacteroides rodentium TaxID=691816 RepID=UPI00046EF653 +-sELEKRIDSLLKGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAMLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMVRLLRTTDEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium cutihirudinis TaxID=1265740 RepID=A0A3D9FVM5_9FLAO +--DLRKELNQIIATKNATVGISIKSIEDKDML-SINGNLKAPLMSVFKFHIALTVLSKVD +EGKLSLDQKIFIKKKDLNEWSPMRDDYPEGNLTLDKLLRYTVSHSDNNGCDLLIKLVGGT +KEVQKFINKQGIKDFVIKVNEKQMET-WKNLYVNTTTPLATTELLEKFYKGEILKETTIK +YLYQIMVETSRGLTWLKAGLPEGTELAHRTGISGTNAMNDVGIVKLPNGKHFIISVYLKE +ITETKEDTEKIIADIAKATWNYf +>[subseq from] Beta-lactamase n=1 Tax=Croceicoccus marinus TaxID=450378 RepID=A0A1Z1FDC8_9SPHN +--TFRRQLFAVAPQAQGRIGVAALDLTTGQTV-SIQGDEPFPMASTSKIAIAATFLAGVD +SGKYSLFDRYPLMVPVASESSKVAPVRAGQTMTAEMLIERMITRSDNQATDALLAVVGGP +QAVNAWARKAGLGRFRIDRDIATLVRSRHVDVRDSTPPEEMVELIAGIHQGKWLSPASRG +LLIGAMTRTVTGSSRIKAGLPRGVSFGHKTGTLNK-TASDVGFVTLPDGRVVVMAIYVTG +QSGP-AARNAKIAEITRTIYNGf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=B2CD50_ECOLX +---------------------------------------SFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVQDH---------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000480A4C1 +-eRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] D-alanyl-D-alanine carboxypeptidase n=2 Tax=Planctomycetes bacterium Pla144 TaxID=2528003 RepID=A0A5C6CJH7_9BACT +--DLASRIQPLIDSFEGEVGVMIKQLETGEEF-EYRSTESMPTASLIKFPLMIATYQAIE +DGKLDLDQRVTLRDEDKVPGSGILTAHFSDGLSLRDVIHLMIVYSDNTATNLVIDQV-GL +PSTAELMKSMGFAETVLNSKVYRRDTRSRKYGLGSTTAKDMVSLLEKLQAGQLVSEHASK +QMLAHLRACDD-TSKFPRLLPPGLTVAHKTGAVSD-TRTDAGIIESRDG-PIALCVLTTN +IESDDNAAELLCANIAKAAYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Oerskovia enterophila TaxID=43678 RepID=UPI0008276110 +-hELDEALRDLERSRSLTVGVSVRG-GGRADY-GYRAAERFPMCSLFKPIAVGALLADKA +YDDAYWSREIAFGPEDLVENSPVTSATTTWRMTPAQLADAALRFSDNTAGNLVLREIGGP +TAVSSFAASLGARATRLDRIEPQLNEATPGDDRDTSTPDDIARIYGALLLERGAGALTAA +RLGDWMLRSTTSGKRFRAGLDGTYELADKTGAGGYGVVNDAGVLWRPGVEPTTLVVMTRT +DSPGATWDDEAVAAITRLVVA-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides TaxID=816 RepID=A0A3E5EGM2_BACUN +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKLPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD +SYETDEDNADIIARISRMVYDA- +>[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI0010FED638 +-------------------------------------------------LACAKLLADSD +KDKSVLTHQVVIKKSDLVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDPRDTTTPVAIVETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTQHKPMVMSIYIQQ +SSASMDERNKAIAIIGKQVFTYf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A126G806_PSEAI +--NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRET-TGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium acidiphilum TaxID=505248 RepID=UPI000688D287 +-------LSALERRSGGQLGVMVRDCATGHGF-GWRQDERFAHCSTFKLSLAAMVLAQID +AGRARGDEVLAYSVLDVLPASPVTEALAGREMSILALAQAAVERSDNTAANLLLARFGGP +AALTAFWRAMGDEVSRLDHNEPMLNRVGLGEVHDTTTPAAMAATLGRVLTGRVLSGASRA +LLWGWMKNCSTGLGRLRAGLPAGWQAGDKTGTEY-GRINDLALVLAPGGAPLAVTAYYLP +GGELRPADEAVLAAVMRIATD-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium sp. ML3W TaxID=1538644 RepID=A0A088EY86_9SPHI +--SLRTNLENIVQLKDALVGIAITGIDKQDTL-GINADRHLPMQSVFKVPIAIVMLSEID +KGNFELDQEIKITKKDMTPWSPIREKYPKGVLTIREILEYTLTLSDNIGCDVILKLLGGP +QVVERYFTNMGFSDISIKINEKTMQSDWESQFRNWATPREINKILQTFYVKNLLSLEQYD +FLWSTMISTNTGLNQLKGQLPKHTVVAHKTGSSGTAALNDVGVILLPNGEYFVISVFVTN +SKENQETNENIIADIAKQAWDYf +>[subseq from] Class A beta-lactamase n=1 Tax=Sandaracinobacter sp. PAMC 28131 TaxID=1715348 RepID=A0A501XJS5_9SPHN +---LEAQFAYLAKQTDGTVGVAVQKVGSTEVM-TLNKGVTFPMASTFKVAVAARIFERID +KGELKLDQIIPVDPKILVGGLAVMTPHDGISLSVHNLLELMITISDNTSTDVLTAQAGGP +AAVTDWLTRHGIKGQRVDADTAHLIYPFNADPRDTSTPEAMVELLMQIQSGKVLSEASTK +ELLAIMGRTSTGDKRLKGLLPIGTPVAHKTGTLMS-IANDVGFITLPDGSQFAIAVFVKG +DTKGSETQERVIAEMARTAYDYy +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SUG7_9BACT +-sELENRIDSLLNGKEATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMAQLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD +SYETDEDNADIIARISRMVYDA- +>[subseq from] Beta-lactamase n=2 Tax=Sphingopyxis sp. FD7 TaxID=1914525 RepID=A0A2Z5UI08_9SPHN +---LQDRIHALWRAFPGKTGIAVQRIDGEWTL-SHRGGELFPQQSVSKLWVALAVLDAVD +QGRLTLDQRVRIGPEDLTLYQPIASRVRAEGMSVRELIEIAITQSDNTANDSLLRTVGGP +DAVRRFIAKKDLGAIRFGPGERLLQAAYLANPPDGASPAAIANALTRLARGALLSPESTE +YLLGVMSRTKSGPRRLKAGLPPDWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGD +TSAPVPARMELMQAVSRAVAEY- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD9213A +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVCFLHRLATGQLLSASSTA +HLLEVMNRTTTFPDRLRSGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE16F04 +--SLDKGIAKLERRTEGRLGVALIDLKDHKLW-SWRGAETFPMQSVFKLPLAVAVLQQVE +AGKFKLDQPITITRKDLSLNSPIARQFKGESYPVRDLIRLAAGQSDNTAADRLMREIGGP +QVVTKMLRDGGIEGMSIDRYERQFQPAALTDKRDAATPEASARFLEGFAEGNWLRPAHTA +FLTKVISESKIGTGRIKAGLPPGSVLAHRTGLGLNHATNDIGIATLPDGRRFVIVTYLAG +SRADAPKREAALAEAARLAVS-- +>[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI000C79764D +-nHLHTELAALASAHPGRVGICVQDPTSPPIC--VNGEQRFSLQSVMKLVVAAAVMRAVD +ERRVALSDRVTVRREDLSVIQPIADIVSERGTSLGDLLRRAVVESDSAATDMLISRLGGT +KAIQAFLGESGLHGIRIDRTERELQTAYLTDPRDTASPRGMVGFLHKLAAGQLLSASSTA +HLLEVMKKTVTFPDRLRAGVPPGWTIGHKTGTSRNGVTNDVGILTAPDGRHVAVAAFVAE +SRTGNEERAAMIAAAARAITAAy +>[subseq from] class A beta-lactamase n=1 Tax=Agromyces sp. Root1464 TaxID=1736467 RepID=UPI0006FC9CE2 +hrRLSDAIAELERATSVTIGVTAIWHDSGRAF-RYRGADRFPMCSVFKTLAAGALVQARG +YDEAYWAGPIPFTSADVVGDSTKLDTT-TWAATPEQMADAALRFSDNTAGNLLLRELGGP +PAVTAFARSLGATRTRLDRPEPEVNEATPGDERDTSTPDDIAFLFQKLLIDQGAGALTTA +RLQEWMLRNTTSGKRILAGLTPPFELADKTGLGGYGVVNDAGVVWRPGEEALTLAILTRT +DRADAPSNHDVLADVTRLIVA-- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium cucumeris TaxID=1813611 RepID=UPI00078786E1 +---LEQKINSILKNKKATVGVSVLGFENGFTY-NKNADKKLPMQSVFKFHIAATVLNAID +QGKLYLDQKIKLDQSNLLEWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLRLLGGT +RTVQKFIDSKGVQGFQIKYNEEDMHKDWNVQYENYSTTKSAVDILKKFYDGKILSKKSTD +YLMKVLWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFVSN +STETDAVNCRMISDISREVWEYf +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. UNC23MFCrub1.1 TaxID=1449068 RepID=UPI0009DE7F62 +--DVSTGLQAVEERYDVTVGVSLLNTGTGETI-SYRGAERFGFASTVKVFLAAEFLRRTP +--EDARDDLVRWTAADIERYSPVTTARLDTGLTAAELAEAAVRESDNTATNLVFDRIGGP +AELDAALSRLGDDVTDIADVEPGLNTVGPDSTGNTTTADAFTTSLAALRGAGSSTDADAA +TLAEWMSGNATGDALVRAGAPSGWTVADKSGGAG-AVRNDIAVVTPPGCPPLVLTVLTRK +NDASAPYEDAAVSESAAVVLN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroidetes bacterium 46-16 TaxID=1895925 RepID=A0A1Q3X0A6_9BACT +----IAKIDSVINSLHANIGIAVTGLDFSDSI-FINANKHYPMQSVYKFPLALFVLDKVD +KGQLSLEMNVHTARGLVDKWSPMVKDFPGGDMTLRDLLTYAISKSDNNACDILFRTVGGT +AVVQKYLDGIGIKGINIAATEAEMKKAFEVQYSNWAEPVAMAHLLKMFYDTRLLSKDNTN +LLMRLMTQSENPDDRIKGRLPPGTVVAHKTGTSGRAATNDIGIITLPGHRHIAVVIFVSD +YKAGLKQGEQAIAEIAKLVWDYy +>[subseq from] Uncharacterized protein n=2 Tax=Bosea sp. PAMC 26642 TaxID=1792307 RepID=A0A126NXW0_9BRAD +-aKLDREIIAIERQSKGRLGVALLDLKDRKTW-SHRGAERFPMQSVFKLPLAVAVLQAVE +AGKLKLDQPVTIKRSEFSLHSPLADALEGESYPLRELIARAAGDSDNTAADFLLRLVGGP +QAVTAMLKAGGITGMSIDRYERMLQPAALSDPRDSATPDASVAFLEALAKGNWLRDPHAA +WLDRVISETMSGPERLRAGLPEKARLAHKTGLGPNHATNDIGLVTLPNGRVFAIAVYLAG +STADAKQREAAHAAVARLAV--- +>[subseq from] Beta-lactamase n=1 Tax=Flavobacterium subsaxonicum WB 4.1-42 = DSM 21790 TaxID=1121898 RepID=A0A0A2MIS9_9FLAO +-sQLQKDIDKIVKNKKATVGVSIIGNNVNDTV-NINPSKHFPLQSVFKFHIAIAVLSEVD +KGNLQLDQKIVVDKKDLLKWSPMRDQYPDGALSLAQILEYTLIQSDNNGCDILLRLLNGP +KFVEDYFIKNNFTDIAIKATEEDMHKDWETQFSNWTTPKSASDVLIAYYNNELLSKGSYD +FLWTTMKATQVGAKRIKGQLPSTTIVAHRTGTSGTAAVNDIGVILLPNGKHFYISVFVSN +SKEDEKTNEKIISDIAKAAYNYf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE2CCDE +--KLDGGIRTIEREARGRLGVALIDLKDRKSW-SHRGQERFPMQSVFKLPLAIAVLQAVE +AGTLRLDQDIRVRRNELALWSPLKKGFKGDEYTVTDLLTRSTGASDNSAADVLMKRIGGP +KVVTTMLNEGGIAGISVDRYEREFQPYIKGEARDSATPEASIAFLEGLAKGNWLREPHDR +LLTDILLKSPTGAQRVRAGLPTGATFAHKTGTGDNSATNDIGIVALPDGRRFAIAVYLAG +AQADATAREAAHAAVAKLAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. NM69_E16B TaxID=2516960 RepID=A0A4S2AXS7_9BACE +--RLENQIDSLLKDKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQGISLDSIVSIKASQMLPYSPLRKKFPNQDITLRKLMQYSISQSDNNACDILIEYVGGI +KYINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAQTMVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDKDNADIIARISRMVYDA- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI00020F3C40 +-dRLRSELTVLANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDQAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTTTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] class A beta-lactamase n=1 Tax=Pantoea anthophila TaxID=470931 RepID=UPI0009FE2C7A +------------------------------------------------------------ +----------------MVNYNPVTMKHIGSAMSLAELSAAALQYSDNAAMNKLLAYLGGP +QYATQFARTLGDTMFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNKLILGSALKDDQKA +TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPLVLTTYFTQ +HDKSAAARKDVLASAARVIAD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SUM3_9BACT +-sELENRIDSLLNCKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNADIIARISRMVYDA- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI001296ACBA +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHGLATGQLLSASSTA +HLLEVMNRTTTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Class A beta-lactamase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E8QUH2_9BACT +--HLAGEVSRLAEHALGTVGVAAYHLETGRWM-TMNGEERFPMASTYKVPIATQILTMVD +QGDLALTDMIEIEQEDVYLTSSAISDLLDDPLSIHNLLELMLQISDNIATDILFEIAGGA +EEITGRMVEVGADGIRVDRTTWALIAAFNADPQDTATPLAMARLLRKIWDQEILSEESSS +LLIDIMYRCQTGEARLKGALPPGTQVAXKTGTIGE-TTNDVGIIDLPDGGHVITVVYIKE +SKPDNPAMEPVIANIARAIHDYf +>[subseq from] Beta-lactamase n=2 Tax=Flavobacteriaceae bacterium (strain 3519-10) TaxID=531844 RepID=C6X4P0_FLAB3 +---LKKQIQQIIKDKNATVAVSVHDFENNKTI-HINGNKKLPMLSVFKFHIALAVLNEVD +EGKLSLDQNIFIKKSDLAEWSPIRDRFPDGNIPLSLLLKYTVAESDNNGCDIVLRLIGGT +GTVQKFIDSKDVKDFTIKADEAQMHRGDEFLYWNVTSTNSANKLLKDFFDKKTVSKPSTD +FLMNTMLETTTGQNKLVAQLPRGLPVAHKTGSSGKNAENDIGIVTLPNGKHYAISVFVSD +SMESEATNTKMIADISKIVFDYf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD88C71 +--SLDKGIAKLERRTEGRLGVALIDLKDHKLW-SWRGAETFPMQSVFKLPLAVAVLQQVE +AGKFKLDQPITITRKDLSLNSPIARQFKGESYPVRDLIRLAAGQSDNTAADRLMREIGGP +QVVTKMLRDGGIEGMSVDRYERQFQPAALTDKRDAATPEASARFLEGFAEGNWLRPAHTA +FLTKVISESKIGTGRIKAGLPPGSVLAHRTGLGLNHATNDIGIATLPDGRRFVIVTYLAG +SRADAPKREAALAEAARLAVS-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SUA0_9BACT +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-WYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNADIIARISRMVYDA- +>[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=C3H3B0_BACTU +----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS +--IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPG------------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Aquimarina algiphila TaxID=2047982 RepID=A0A554VNG5_9FLAO +-eTLKQKIEDIINSKNAIVGVAINGMEIKDTL-NINGQRHFPMQSVFKFPIALTILSEID +KGNLSLDQKIDIKKSELLPWSPIRKKYSEGVLSIAEIIKYTVALSDNVGCDVLLRLLGEP +QTVENYFSSLGFKDFSVKINEETMQNNWDLQFLNWTTPKEANRILTTFYKNRLLTQESHD +FVWNVMKGTKTGKNRLRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPNGKYYTISVFITE +STESFETNEKMISDISKATWDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium polytrichastri TaxID=1302687 RepID=A0A1M6ZVA5_9FLAO +---LDKKINSIIKDKKATVAVSVLGFENAFNY-NKNGEKKLPMQSVFKFHIAAAVLDFVD +KGKLSLDQKISLNKSNLLEWSPLRDKYKDANVPLSEIIDQTVAMSDNNGCDILLQLIGGT +QTVQKFMDSKGVKGFQIKFNEEAMHKDWNVQYENYSTTNSAVQVLKKFYDGKLLSKKSTD +YLMKVMLGTQTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYAIALFVSN +STETDAVNCKVISDISKAVWDHf +>[subseq from] Beta-lactamase n=1 Tax=Ignavibacteriae bacterium TaxID=2026749 RepID=A0A2E0VZJ3_9BACT +-nALQRQFEQLADTIKGNIGVSALNIETGESI-SFNGNEKFPMQSVYKFPIAMVMLNEID +NGNFSLKDTILINESEYIPHSPIRDKYPNGILTIKEILEYNISQSDGTACDVLLRLLGGT +DKVEKSIHALGVKDIAISTTEMVQVANDTIQYQNWATPNAMNRLLEIFQNGNYLTEQSKN +LLLGFMSSNKWFDRRIKRLLPKETKLAHKTGTSSTRATNDVGIITLPDGSHLAISIFISD +SYDSQKKREMTIAQAAKAAYDYw +>[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=A0A508WY16_9RHIZ +-nHLHTELAALASAHPGRVGICVQDPTSPPIC--VNGEQRFSLQSVMKLVVAAAVMRAVD +ERRVALSDRVTVRREDLSVIQPIADIVSERGTSLGDLLRRAVVESDSAATDMLISRLGGT +KAIQAFLGESGLHGIRIDRTERELQTAYLTDPRDTASPRGMVGFLHKLAAGQLLSASSTA +HLLEVMKKTVTFPDRLRAGVPSGWTIGHKTGTSRNGVTNDVGILTAPDGRHVAVAAFVAE +SRTGNEERAAMIAAAARAITAAy +>[subseq from] Uncharacterized protein n=1 Tax=Oerskovia sp. Root918 TaxID=1736607 RepID=A0A0Q9BXL7_9CELL +---LDDALRDLERSRSLTVGVSVRG-GGRADY-GYRAAERFPMCSLFKPIAVGALLADKA +YDDAYWSREIAFGPEDLVENSPVTSATTTWRMTPAQLADAALRFSDNTAGNLVLREIGGP +TAVTSFAASLGARATRLDRIEPQLNEATPGDVRDTSTPDDAARIYGALLLERGAGALTAA +RLGDWMLRSTTSGKRFRAGLDGTYELADKTGAGGYGVVNDAGVLWRPGVEPTTLVVMTRT +DSPGATWDDEAVAAITRLVVA-- +>[subseq from] Beta-lactamase class A n=2 Tax=Chryseobacterium rhizoplanae TaxID=1609531 RepID=A0A521FKJ9_9FLAO +---LEQKINSILKNKKATVGVSVLGFENSFKY-DKNADKKLPMQSVFKFHIAAAVLNAVD +QGKLSLDQKVALNKSNLLEWSPLRDQYPAGNIPLSEVIEYTVAKSDNNGCDILLRLLGGT +QPVQKFMDSKGVKGFQIKYNEEAMHKDWKVQYENYSTTQSAVDVLKKFYDGKLLSKKSTD +YLMQVMLSTSTGLNKMVERLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN +SMETDAVNCRMISDISKEVWVYf +>[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI000360B786 +-nHLHTELAALASAHPGRVGICVQDPTSPPIC--VNGEQRFSLQSVMKLVVAAAVMRAVD +ERRVALSDRVTVRREDLSVIQPIADIVSERGTSLGDLLRRAVVESDSAATDMLISRLGGT +KAIQAFLGESGLHGIRIDRTERELQTAYLTDPRDTASPRGMVGFLHKLAAGQLLSASSTA +HLLEVMKKTVTFPDRLRAGVPSGWTIGHKTGTSRNGVTNDVGILTAPDGRHVAVAAFVAE +SRTGNEERAAMIAAAARAITAAy +>[subseq from] class A beta-lactamase n=1 Tax=Rudaea sp. 3F27F6 TaxID=2502208 RepID=UPI0010F8D21D +--DLQGRLEALAERAPGVLGVAVLDLQSGRSW-RVNADRGFPMMSTFKAALGATVLDRVD +HGALSLDRKVTLTRADMRNGPEAIRKEFDAGFDVRRLLDAAVSESDNAAADALIRLLGSP +AAVTAFLRAHGVDGMRVDRDEAGLAHAYLADPRDTSTPDAAVVFLRKLWRGELLARESTA +LMLEMMTHSPTVPNRLKGGVPAGARLAHKSGTSDTAAHNDIGILSWPDGRTVIVAGFLTA +SPASADERDAIFATLTREVTQ-- +>[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium medicae (strain WSM419) TaxID=366394 RepID=A6U9H5_SINMW +-nHLHTELAALASAHPGRVGICVQDPTSPPIC--VNGEQRFSLQSVMKLVVAAAVMRAVD +ERRVALSDRVTVRREDLSVIQPIADIVSERGTSLGDLLRRAVVESDSAATDMLISRLGGT +KAIQAFLGESGLHGIRIDRTERELQTAYLTDPRDTASPRGMVGFLHKLAAGQLLSASSTA +HLLEVMKKTVTFPDRLRAGVPSGWTIGHKTGTSRNGVTNDVGILTAPDGRHVAVAAFVAE +SRTGNEERAAMIAAAARAITAAy +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium detergens TaxID=1145106 RepID=A0A420BFH0_9SPHI +--QLKKQLQEIIAQKNATVGISIKGIAAKDTL-SINGNLKMPMMSVFKFHIALAALHQVD +KGKLRLDQKFFIKKDELLEWSPMRDDYPNGNLTLDQLLRYTVSHSDNNGCDILLKLLGGP +EKVQDFISQQGIKDITIKVNEQQMRT-WDNLYLNTTTPIATTLLLEKFYQGKILKKETSS +YLYQIMVETSRGTTWMKAGLPQGTELAHRTGISNRAAMNDIGIVKLPNGHHFTLSIYLMN +ITEKREDSEKLIADITGATWKYf +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. PASSN1 TaxID=2015561 RepID=A0A257GDP7_9SPHN +--AIEQQVAAIVAQGRGRIGVAAVDLDGGGQI-MINGDMPFPMASTAKVAIAATYLAGVE +QGRLRLDQQFPMMVPVAESRGAVAAVRPGEVMTAQSLMELSITRSDNHATDGLIAAVGGI +NAVNTWLSRIGVSGQRLDHTMATLVRVTTIDTRTSSTPRAMAQLLAAIDRGGALSPESRA +VLLDTMTRTSTGRNRIRSGLPEGVVFAHKTGTLS-GVTDDVGIVRLPDGRHLAIAIFVTG +PEG-HTAHAGLIAQIARVLYDGy +>[subseq from] class A beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=UPI0013A56F02 +------------------------------------------------------------ +---------------------PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KEQTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE4FDA7 +-dRLQARLQALAEAHPGRLGICAQDADSAPVC--INGDQRFSLQSVMKLVVGAAMMRAAD +RGRIRLDDPVTIRREDLSVIQPIADIVAARGTTIADLVRRAVVESDSAATDVLISRLGGI +AALRTFLAEAGIAEIRIDRTERELQTAYLYDKRDTATPRAMAKFLTMLASGRLLEPASTR +QFREIMAATVTFPDRIRAGTPEGWSVGHKTGTSQNGVTNDVGILTAPDGGFLVIAAFLAE +STAPAPGRAAVIAEAARAITASy +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Cloacibacterium normanense TaxID=237258 RepID=A0A1E5UHB1_9FLAO +-aELKKEISKITEGKKATVAVSVLGIDFPFQYnNNNAEKKLPMQSVFKYHIALAVLDLVD +QGKLSLDQKVFIKKSELLPWSPIREKNPEGNMPISELIEYSVAMSDNVGCDVLLRLIGGP +KVVHDFLIYKGAKDTQIVYNEEIMQSAWKNQYENYTTMKSATRLLKDFYKGKILSKKSTE +FLLGVMYRTSTGLNKIVEQLPKSAKVAHKTGSSGTGAENDIAIITLPNGKTYAIAIFVSD +SMETWEVNCKMISDISKVVFE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. C05 TaxID=1945855 RepID=A0A1V3NXT3_9GAMM +--RLQQKLDALAQRAPGTLGVAVLDLQSGTEA-GVNAGQAFPMMSVFKAPVAAAVLSRVD +AGKLSLQQQVSVSRADVLSGSPSIGAHFRGEFTVEQLLKAAVSESDNTAVDALVKVVGGP +QVVTAFLRAHGIDGMRVDMDEAGVARAFLDAPTNRSTPDAAVGFLRKLHDNELLTQASTQ +YLLGLMAAQTI-PNRLRAGVPQGVGLADKTGTSGTAAYNDIGILSGPDGHTVIVAAFLTD +SHASDAQRDALFADIARAAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Nitratireductor soli TaxID=1670619 RepID=UPI00065E998B +--RLQAQLQALTDKHPGRVGICVED-ASLKPI-CVNGDQRFSLQSVMKVVVGVAVMRAVD +DGRLKLDDPIVIQREDLSVIQPIADIVAEQGTTIGDLVARAVIESDSAATDVLILELGGA +KAVQSLLDGAGIKGIRIDRTERELQTAYLKDERDTTTPRGMTAFLSALATGELLSPASTR +NFLNVMARTKTFPDRLRAGTPKTWTVAHKTGTSQNGVTNDVGILTAPDGGKIAISVFVAE +STASNDLRAAVIANAARATVAAy +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Aminicenantes bacterium TaxID=2052149 RepID=A0A3D4P0G7_9BACT +--RLRRRVEDVIKRAEGEVGVALRHLESGQSL-EINAGSRFPMASTFKLPVLVEIMAQVK +EGKLSLEDEVSVQKTEQHLGSGMLSSLTAPGLTVRNLANLMMMISDNSAADILLAKA-GP +ENVNKRLRQYGVEGISVNRSCQELIMKFILDPRDQSTPAAMNRVLEKVYKKEILDPESCD +LILSIMLQCQTGEGRIKGKLPPGAPVAHKTGTIA-GTVNDTGIITLPDGGHMAITVFTKG +FEDETEDVEKIIAEIARLVYDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Nitrospirillum amazonense TaxID=28077 RepID=A0A560HCX2_9PROT +---LQARLDRLAHDFPGHAGIAVRDPATGAVA-GVRADQRFPEQSVFKLTVAIALLDLVD +KGATDLDHKVTLYPEDRSVWQPLAKNITPGGTTLGDLMVRMVADSDNIAADTVLRLIGGP +ATVQAALNARGLEGIRVDRDERHLQSAYLSDPRDTATPAGMALLLERLNKGDLLSPASTR +RLLDILDHTTTQPHRLKAGLGAGWAVAHKPGAGPTLANNDVGLMTAPDGGRYAVAVYVAS +VHGPREGADAFIAAVARAVVESw +>[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium sp. JRR 20_7 TaxID=2183917 RepID=A0A495NQU2_9FLAO +-nELRQQLSQIISSKNAAVGLSIKGIEDKDTL-SINGNLKAPMMSVFKFHIALTVLDKVD +QGKLSLTQEIFIKKKDLHEWSPMREDYPDGNLTLDKVLRYTISHSDNNGCDILIDVLGGT +KEVQKFINKQGIKDFVIKVNEQQMRT-WENLYVNTTTPLATTVLLEKFFKGQILKESTTK +YLYQIMVETSRGLTWMKAGLPKNTELAHRTGMSGTNAMNDIGIVKLPNGKHFILSVYLKN +ITEKQEDTEKVIADITKATWDYf +>[subseq from] Beta-lactamase n=2 Tax=Legionella waltersii TaxID=66969 RepID=A0A0W1AM06_9GAMM +-tDIQKRISAIEKSSNAIIGVTAIYVEKNKVI-SHNGSQRFFMASTIKLPIAIALLHRVD +EEKESLNRIVKLNAKHSVPGSGVLHYMFEKNISMKQILKYMLINSDNSASDVVLQAAKGP +SAVTKRMYALGFKNIVINRSIIQMLMRFQNDVRDTTTPDDMAKLLVKLYKGDVLSESSTN +LLLNIMESCRTGRSRIRGLLPPRVKVAHKTGTWGYRFTSDVGIITLPNKGHIAIAVYIKS +KAVSDYPRSRAIAQISKAIYDHf +>[subseq from] class A beta-lactamase n=1 Tax=Porphyrobacter tepidarius TaxID=60454 RepID=UPI000A3B4682 +--RLAAELMIIEAAGNGTLGVALFNTVTGASV-GLNQDRRFGHASSFKFSLAALLLQRHA +AGLIDADRDVMWSEADMLPYAPFTRERMASGATLRELARAAQTTSDNPAANILLRELGGP +VALTAFWRSIGDEVSRADRYEPALNNVPTGEFRDTTTPAAMARNVARIIYGDVLPEKERA +ELKGWMIETRTGARRVRAGLPQGWIAGDKTGTSGY-NYIDIGFAEGPKGPPITFACYFRA +RQRELASGETTLARVGRVI---- +>[subseq from] class A beta-lactamase n=1 Tax=Vibrio vulnificus TaxID=672 RepID=UPI000D4E6770 +-----------EDELGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLT----- +------------------------------------------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudofrancisella aestuarii TaxID=2670347 RepID=UPI000E65737A +--QVQNKISRVQGKFGGKVGIYTIDRNDWKNF-KYNENFQFPICSVYKFLVVGAILKESM +TNPDLLDKKIKIHEGDIIGYTPVTSKNINKSLSVKDLSKAAI-LSDNTAANLLINELGGL +KKLNEFIISLNDKDTIITANEPNINNINLHDNFNKTSPKSIARDINKIAFDDVLDKRHQK +LFRKWLKENDTGKNRIAYSLPEGWQIGDKTGTCEYGSTNDVAILWPKGKKAIIMSILYTQ +ADKNAKPKDEIIQATSKIVLDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium shigense TaxID=297244 RepID=A0A1N7IQZ5_9FLAO +-qQLKKDLQQIISTKNATFGISVKGIEDQDTL-SINGNKRMPMMSVFKFHIALTVLDLVD +KGKLQLNQKFFIKKEELLAWSPMRDEFPEGNLTLDQLLRYTVSHSDNNGCDILLEIIGGT +QTVQKFINKKGIKDFTIRFNEQQMSGE--NLYTNTTTPIATTELLEKFYKGKVLKENTTR +YLYKIMVETSRGLTWMKAGLPEGTELAHRTGISGRAAMNDVGIVTLPNGKHFILSIYLKN +ITEDRVVTEKTIADITKTVWEYy +>[subseq from] Beta-lactamase n=1 Tax=Anseongella ginsenosidimutans TaxID=496056 RepID=A0A4R3KL40_9SPHI +--TLESQISHIAKEVNGRVGVCALVLETGEAV-SYNGGERYPMQSVYKFPIAMAVLEKVD +RGELTLDQQVRIDTTEYIPHSPLRDKFPGGTLTVRQLLHYNTAESDGTACDVLLRLLGGT +KKAQRYVRRLGIKNMAIATTEQIQVANDLIQYRNWSTPKAMTELFRIFYQDKPLSEESTA +LLMEHLSPSGVWNRRIKGLLPPGTPVVHKTGTAGTRATNDAGIITLPNGNHVAITIFLAD +SHAVQKDREATIAKIARAVFDQy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium elymi TaxID=395936 RepID=A0A3D9DDU8_9FLAO +-qQLKKELQQIISTKNATFGISVKGIEDKDTL-SINGNKRMPMMSAFKFHIALAVLDQVN +KGKLRLNQKFFIKKEELHPWSPIRDGFPEGNLTLDQLLRYTVSHSDNNGCDILLEIIGGT +QTVQKFINKKGIQDFTIRFNEQQMSGE--NLYGNTTTPIATTELLDKFYKGKILKEATTK +YLYTIMVETSRGLTWMKAGLPEGTELAHRTGISGRAAMNDVGIVKLPNGKHFILSIYLKN +ITEDRAATEKTIANIAKTVWEYy +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDCB5F5 +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMAGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. IC081 TaxID=304378 RepID=A0A514WM39_9SPHN +-nDFERRLAGVAEASQGRIGVAAVDLSTGRTV-DVLGSQRFPMASTSKVAIAATFLDGVD +KGKWSLSSEYPLMIPVASASSPIAPVRPGAYMSARQLLELMITRSNNYATDALLKVVGGP +AAVNAWVRRAGIEDWHIDHDIATLVRAKVVDKRDSATPLAMVELLTGIYQGKWLTPSSRS +VLMGAMGRCVTGRNRIRAGLPSGVTVSHKTGSLNN-TSSDIGFIETADGRAYAVAIYVTG +QG-SRPAREARIASIARTLYEGy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D5C9I1_ECOLX +------------------------------------------------VMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNH-------------------- +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Myroides guanonis TaxID=1150112 RepID=A0A1I3PIS6_9FLAO +-eNLRDNIEAITKSKNAIVGLAIQGTNPEDTL-SIRGTEHFPMQSVFKFPIALTMLSEID +KGNFSLDQKITISKNELLPWSPLREEYPEGGLSIANILRYTVMSSDNVGCDVLLRKLGGP +IAVENYFHKRGFNDFEVKINEETMQNNWDMQFLNWTTPKEANNILKAFYENKQLSHKNHE +FIWNIMKETETGKTRLKGQLPKGTLVAHKTGWSGSAAVNDIGIVFLPNGNYFYISIFITN +SIEDTETNEKIIADIAKSAWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Porphyrobacter cryptus TaxID=196588 RepID=UPI00041C0972 +---LAAELRIIEAAGDGTLGVELFNPVSGVAV-GLNQQQRFGHASSFKLSLAALLLQRHA +AGAIDADRRVTWGKADLVGHSPFTLERLPRGASLRELARAAQVTSDNGAANILLRALGGP +AALTAFWRSLGDSVSRLDRYEPELNLVPASEFRDTTTPAAMACTLARIVYGEVLPEAERA +ELKGWMVETQTGMRRVRAGLPKGWVAGDKTGTSGY-CYVDIGFAEGPKGGPITFACYFRA +RQEMLPRGEQVLARVGRII---- +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter salegens TaxID=1737568 RepID=UPI000B330C8B +-----RLVAQLADGSNGRIGVAAVDLSTGQEV-GVLGDQRFPMASTSKVAIAATYLEGVD +KGRWTLTRELPLLVPVRSASSKAAPVKEG-QYTALELIDLMLTRSNNAATDSLLHAVGGP +AAVNDWARRAGIKGFNLSRDIATLVRASHIDIRDSSTPRDMVLLLTGLYQGQWLSAESRR +VLIDTMERCRTGTHRIPALLPENVRVAHKTGSLNN-TSSDVGIMMAPDGRSIAVAIYVTG +QG-SRANREAKIASIARAIYDGy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D5C9D9_ECOLX +------------------------------------------------VMAVAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNH-------------------- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Flavobacterium sp. KBS0721 TaxID=1179672 RepID=A0A1S8ZZJ0_9FLAO +-nELRQQLNQIISSKNATVGISIKGIEDKDTL-SLNGSLKAPMMSVFKFHIALTVLDKVD +QGKLSLTQEIFIKKKDLHEWSPMREDYPDGNLTLDKILRYTISHSDNNGCDILIDVLGGT +KEVQKFINKQGIKDFVIKVNEQQMRT-WENLYVNTTTPLATTVLLEKFFKGQILKESTTK +YLYQIMVETSRGLTWMKAGLPKNTELAHRTGISGTNAMNDIGIVKLPNGKHFILSVYLKN +ITEKQEDTEKIIADITKATWDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000739857D +-qELKNQLQQTIASKKATVGVSIKSIEDKDTL-NINGNLKMPMMSVFKFHIALTVLNEVD +KGKLKLDQRFFIKKEELLEWSPMRNDFPNGNVTLDQLLRYTVSHSDNNGCDILLNILGGT +EKVQTFINQQGIKDFTIKVNEQQMAT-WDNLYINTTTPIATTLLLEKFYKGKVLKKDTTK +YLYQIMTETSRGLTWMKAGLPEGTELAHRTGISDRAAMNDIGIIKLPNGKHFILSVYLMN +ITEKREDTEKIIADIAKATWNYy +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8LPJ1_9BACT +------DVTQIASLAKGHVGASAVVLETGETVaSLNAQDHFPMQSVYKLPISMAVMKQVD +AGKINLDQKVAVTKGDFVRYSPIRDRNPNGTITVSELLRFAISESDGTASDVLMKLAGGR +IPVQMYVTDLAVTDMIVLNTERELGQDWQVQYRNSATPEAAIALLRALHEKRGLSESSQA +LLLKYMIESTPGTKRIKGLLPTGTIVAHKTGTSGTAATNDIGIITLPNGKHLAIAVFVSD +SPADEATREGVIAKIAKAAWD-- +>[subseq from] class A beta-lactamase n=1 Tax=Chitinophaga sp. O9 TaxID=1233460 RepID=UPI00136FF661 +-----RAYATIASGIKGTVGISSVVLETGAAA-GLRTNEHFPMQSVYKFPIAMAVLHEVD +KGRLSLQQPVRVLPSDLIPHSPLRDAHPAGNYSIAELLRLNVAESDGTACDVLLRLLGGP +EKAGQYVHSLGITDISIATTEQVQVPDEMVQYRNWSTPAAMTALLKKFYTGKLLSDSSYH +FLLHLMVTSTPGAKRLKGLLPKDAVVAHKTGTSGTRATNDAGIITLPNGHHLLISVFVKD +ARADLAQREATIARIAEATWNYy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Serratia sp. 251B4_12EESBL TaxID=1535668 RepID=A0A076V860_9GAMM +------------------------------------------------------------ +----LLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDERDTSSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTTWIVGDKTGSGDYGTTNDIAVIWPANHAPLIL------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI000D19B391 +---AAKSFDQIEQDNDTIVGVYGINTSNGKVI-QHRSDERFAFASTYKAISSGILLQNTP +--TSELNKKITISKDDIVAYSPVTEKYVGKQMTLRALIKASMLQSDNTANNKIIEEIGGI +KGFQQALKQRGDNISNPQRLEPDLNLYDPQSTADTTTPKMAATTLNHLLASENMSRPNLE +LLKHTMIHNETGDTLIKAGASKDDVVGDKSGQGTYGSRNDLAFVYPENQKPIILAIYTKK +TDKDAKPDDKVIQTAAEKAIK-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SF45_9BACT +---LPDQIERITAGKHALVGIAVAAADGKEVL-TIQGDKRFPMQSVFKFHIALAVLSAVD +EGKFTLDQQVEILKKDLLPWSPLREEFPEGGFSIQSLLGYTVSQSDNVGCDALLRLLGGP +QVVEGFIKKNQISDISIQINEETMQSNWDLMFQNWTTPRAANEVLVKFYSQRQLSPESHA +FIWRLMRETQTGAGRLNGQLPEGTTVAHKTGSSGTAAVNDIGIIFLPDGNYFYISTFITE +STEDEATNDRLIADIARVCYDYf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SEV2_9BACT +---LPDQIERITAGKHALVGIAVAAADGKEVL-TIQGDKRFPMQSVFKFHIALAVLSAVD +EGKFTLDQQVEILKKDLLPWSPLREEFPEGGFSIQSLLGYTVSQSDNVGCDALLRLLGGP +QVVEGFIKKNQISDISIQINEETMQSNWDLMFQNWTTPRAANEVLVKFYSQRQLSPESHA +FIWRLMRETQTGAGRLNGQLPEGTTVAHKTGSSGTAAVNDIGIIFLPDGNYFYISTFITE +STEDEATNDRLIADIARVCYDYf +>[subseq from] Beta-lactamase n=1 Tax=Dyella sp. YR388 TaxID=2135665 RepID=A0A3M0FFM7_9GAMM +--VLQHALEALAQRAPGTLGVAVLDLRSGAAA-GVDADRAFPMMSVFKAPVAAAVLARID +EGSLSLQQSVTVTREQVMGGSPSIGAHFRGEFTIDELLKAAVSESDNTAVNALIRAVGGP +GVVTTYLHAHGIDGMRVDMDEAGIAQAFLADPRNRSTPDAAIAFLRKLVQGELLSPVSTQ +RLLAMMEAQTI-PNRLRAGLPAGLRFADKTGTSGTAAFNDIGIIRWPDGRTVLVAAFLLD +SPATDSQRAALFADIARTVA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Bosea thiooxidans TaxID=53254 RepID=A0A0Q3I6M1_9BRAD +-dKLDKGIVAIEAQAEGRLGVALLDLRDRKQW-SHRGTESFPLQSVFKLPLAVAVLQQVE +AGKFKLDQPITVTRKDFSLHSPLAKTFKGERYPLSELVRLAAGQSDNTAADLLMREIGGP +QVVTNMLRDGGITGISIDRYERQFQPAALKDKRDAATPEASVLFLEAFAKGNWLRPAHTA +FIEKIISETKIGADRIKAGLPAGSRLAHRTGLGMNHATNDIGIATLPDGRRFAIAIYLAG +SRADANEREAAHAAVARLAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=UPI0009B528F1 +----------------------------------------PPLDSTVKSIACANVLAKVD +AKKLSLNHSMVVTKKNLVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP +EALTAFMRSIGDTVTRSDRYEPELTVNSVDDLRDTTTPDAMSKSIKKILTGEVLSDSSKA +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGIRGITSMVWSNNHDPVFISIYVRK +ADTSLDERSAVIRTLGSHIFDEy +>[subseq from] Beta-lactamase class A n=2 Tax=Tenacibaculum sp. MAR_2009_124 TaxID=1250059 RepID=A0A1H4SIC1_9FLAO +---LKQQIHKVLKNKKAHVGVAIEGVHPKDIV-SINGDDHLPMQSVFKYHLALAVLHQVD +LGKFDLNESISIDKKTIAKWSPLRKKYPNGAVTLAEIIKYTVAWSDNIGCDLLFELVGGL +KAVENYLHKIGIKDIAIVHNEINMQAQWDRQFENWTTAKAANKTLKLFYKNNLLSKKSYN +FLLDVLKGTQTGKKSIRGFLPKDTIVAHKTGHSGTGAVNDIGIVFLPNGSHFYLSVLVSN +STEPDTTNQKIIAEIGKLAWDYf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SSZ0_9BACT +-sELENRIDSLLNGKKATAGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMAQLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD +SYETDEDNADIIARISRMVYDA- +>[subseq from] Class A beta-lactamase n=1 Tax=Empedobacter sp. MRS2 TaxID=2491114 RepID=A0A4Z1BQY8_9FLAO +-eSLRTEINQIISSKNLTAGISLKNLKNKDTL-SINGNQMMPMMSVFKFHIALAVLHEVD +QNKLQLNQQFFIKKEDLLPWSPILEDNPEGNLTLDQLLRYTVSHSDNNGCDILLKIIGGT +KTVQNFINNQGIKDFVIKVNEKEMQT-WDNLYLNTTSANATTKLLEKFYSNKVLKKTSTT +YLYQLMVETSRGLTWMKAGLPTNTELAHRTGISDTNAMNDIGIIKPINHQPIILSIYLKN +ITEERTETEKVIADITKAVWNYy +>[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia subsp. philomiragia ATCC 25015 TaxID=539329 RepID=C6YWK1_9GAMM +--TLDDSFKNLEDEYHGKLGIYTLNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM +QHKGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL +EKLNKLVAKLGDKDTIIKNDEPKINHTKPDSNINKTTPKAITQDIYNLAFGNILDKKHRE +IFIGYLQKNNTGANRIAYSMPKNWTIGDKTGTCGYAATNDVAIIWPQNKPPFALSILYTN +PSVKAPSNEKIIQQASKLVSE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium sp. 90 TaxID=2135622 RepID=A0A4R1JS72_9FLAO +-nELRQQLNQIIASKNATVGISIKSIEDKDTL-SINGNLKAPLMSVFKFHIALTVLNLVD +EGKLSLTQEIFIKKKDLHEWSPMKEDYPDGNLTLDKILRYTVSHSDNNGCDILIDLVGGT +KVVQKFINKQGIKDFVIKVNEEQMKN-WKNLYINTTTPLAATELLENFYKGEILKEETTK +YLYQIMVETSRGLTWLKAGLPENTELAHRTGISGTNAMNDIGIVKLPNGKHFIISVFLKN +ITESKENTEKIISDIARATWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Nocardia crassostreae TaxID=53428 RepID=UPI000B0674D5 +------------------------------------------------------------ +------------TEADLLEHAPFTSQHVTTGMTIRDLCDAAIRYSDGTAGNLLLRELGGP +AALTAFTRTLGDSVTRMDRIEPDNTTALPGDPRDTSSPRALGTDYQQIVLGTALPPDQRT +FLRDLLERNTTGNQRIRAAIPQGWPVADKTGTGDYGTLNDIAITWPPNTPPLVIATMSDR +PTANAEYRQALLADAAALVVS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=A0A3Q8GRR3_9ENTR +------------------------------------------------------------ +---------VEIKKSDLINYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGKALAETQRA +QLVTWLKGNTTGSASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEDHAPLIL------ +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Xanthomonadaceae bacterium TaxID=1926873 RepID=A0A4Q2XS80_9GAMM +------ELRALEQNANGRLGAYVLDPVRGTAF-GWRENERFTHASSFKMSLAAMLLSKAD +AGQIDLRETLLWTKEDMLSVSPVTTVNLGKGLSVRELARATLVTSDNTAANVLMRRFGGP +SQLTAFWRSIGDKSSRLDRYEPELNVTPPGTDLDTTTPAAMAATTAALVHGTILAADSRA +MLRAWMAEVKTGQDRIRSGFPTDWISGDKTGTGIGKTTH--------------------- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Erythrobacter sp. SCN 62-14 TaxID=1660099 RepID=A0A1E4B2J5_9SPHN +-----------MDSLGGTLGAEIFEPETGMAV-GINQDRRFGHASSFKFSLAAMLLAKHA +AGAIDADKKVMWSERDMVEHAPFTRERIASGATLRELAEATQVTSDNPAANILLRALGGP +AALTGFWRSLGDEVSRIDRFEPDMNNVPEGEFRDTTTPAAMARTVARILYGDALPEAERA +QLRQWMIETQTGARRVRAGLPKDWVAGDKTGTSGTSNFIDIGFVEPGKGRPITFAAYYRA +RSEVSASAERVLMRVGRVI---- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina sp. Aq135 TaxID=1191734 RepID=UPI000D561AFE +---LLKKIEQIVSDKNAVVGVSIIGNNGKDTL-SLYGDKRFPMQSVFKFHIALAVLSEVD +KGVLSLDQIVEIDKDELLPWSPLRDENPNGGFTIKRLIQYTVSHSDNTACDVLIRLIGTP +KTVEEYIKKSGIEDIQITFNEEKMQAKWENMFQNWTTPNAASETLKIFFENNLLSKSSYD +FFWKTNTETTTGKGRIRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPDGKYFIISVFVTD +SQENFKTNQEIIAAIAKATYDFy +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD2C84E +-dRLRSELTVLANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTTTFPDRLRSGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013A5A2BA +------------------------------------------------------------ +----------------------VTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTDFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=A0A411KFM3_STASC +-nSTNNDIEKIEKKYGANVGMYALNTQNGKEL-SFNENKRFAYASTLKAISSAMLLEQTP +--YNKLDKKIHINKDDIVPYSPVLEKYIGKEITLKKLIEATMLFSDNTAKNKIIDELGGY +EQVKTRLIDLGDTTTYPSRKEPDLNFYSPKDKRDTSTPLAYGKTLKKLIADGDLSKANKD +FLLDLMLKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVAFVYPDGQKPIILVIFTNK +DR--------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Azospirillum sp. B4 TaxID=95605 RepID=UPI00034DF259 +--ALQARLDQLAHDFPGRAGIAVRDPATGAVA-GVKAQERFPEQSVFKLTVAIALLDLVD +KGAMDLKRKVTLYPRDRSVWQPLAKNITPAGTTLDDLMARMVADSDNIAADTVLRLIGGP +AAVQAALTARGLDGIRVDRDERHLQSAYLNDPRDTAQPAVMALLLERLDKGELLSPASTR +RLLDILDHTTTQPNRLKAGLVAGWTVAHKPGAGPTLANNDVGLMTAPDGHRYAVAVYVAS +VQGPRERADAFIASVARAVVASw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales TaxID=356 RepID=UPI00082A041E +--RLSREIVAIERDANGRLGVALLDLKDRSLW-SHRGSERFPMQSVFKWPLAIAALQAVE +AGKLRLDQPVTIKRSEFSLHSPLAKAFKGEAYPVRELIALAAGESDNTAADILMREIGGP +RAVTAMLKAGGITGISVDRYERQFQPAALKDPRDSATPEASVAFVEAQAKGNWLREPAHS +ALIDITLETKSGPDRIRAGLPQGARFAHKTGAGLNHATNDIGLVTLPNGRVFAIAVYLAG +STADAKAREAAHAAVARLAVS-- +>[subseq from] Uncharacterized protein n=1 Tax=Sphingobium ummariense RL-3 TaxID=1346791 RepID=T0J0V3_9SPHN +--RLIAELERFTKLSDGTVGIAVRDLSSGEEL-AVNGDTLFPMASTYKVAVAGRIFSLID +AGQMTLDTMLPLDPA-LVSEGGVADLHPGAALSVHNFLELMLTRSDNNATDVLVARAGGP +QAVNAWVHGIGVKGLRVDSNTAGLLYTFAQDPRDTATPRAMNQLLSAIQLGKALKPASTA +ALLAIMERCRTGQGRLPAMLPPGTRLAHKTGSLN-GLGNDVGIVSLPDGRIFAISVFVMK +DHEGHAMRDRIMAEAARAAYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Rhizobium meliloti (strain 1021) TaxID=266834 RepID=Q92Y19_RHIME +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia fergusonii TaxID=564 RepID=UPI0011198FFE +------------------------------------------------------------ +------------------------AKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000B49FD89 +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. BPTF-M16 TaxID=2169535 RepID=A0A411ZE97_9SPHN +--RLAAKLNIIEAAAGGTLGATFLNTSTGISL-GINQSARFGHCSSFKLSLAAMTLWRDE +QGLDDAERRVTWTQDDLMFVSPFTTRRLDEGATLRELAEFTQKYSDNAAANILLREFGGP +ETLTDFWRMLGDDASRLDRSEPALNNVPPGENRDTSTPDAMARTVSALCFGDTLSEDGRD +TLKQWMIDTPTGAKRVRAGLPEDWLAGDKTGTSIGSLYVDIGFVEPPNRPPLTFATYYRA +RETHDPASQKVLADVGRVLAE-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina sediminis TaxID=2070536 RepID=UPI000CA05BA2 +-nTLRQKINQVLEGKSTTVGVAITSSNPNDTI-SIHGDMHLPMQSVYKFHLALAVLHQID +QGKFNLDEKITIDQKLVDSWSPLRKKYPNGAISLEELLTYTVSLSDNLGCDVLFKLLGGT +EAVQSYINEIGIKDIAIIHTEFKMQAEWDRQYENWTTAKAANKILQLVFEDDLLSPKSYD +FIINVLKETKTGKKSIRGLLPAEAIVAHKTGHSGTGALNDIGIIFLPNGTHFYLSVLVSD +SMENNETNQKIIAEIAKLAWDYf +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. KEM-5 TaxID=2486356 RepID=A0A5S3PQH0_9SPHN +--RLAAKLAILERALGGTLGAAFYDVEQGLTL-THNAELRFPLCSTFKFSLAAMVLMMEQ +NGTLDTSQHVTWQDSDLLSHAPFTRERGAQGATLLELARAAQVASDNTAANLVLDRVGGP +AALTAFWRALGDDVSRLDRMEPQLNAVAEDELRDTTTPAAMVSTLTKLIASDPLGAQRQA +ILRQWMQDTATGSKLVRAGLPPAWEAGDKTGATDAGARADIGYTLSPGGTPVMFALYYRA +DRPPQTEISRTFAEVGRVL---- +>[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A525JKP1_9CAUL +-kRLDTEVAAIAQRAPGALGFALMNLESGEFW-VRLGDRAFPMQSVFKLPLGAAVLSEVD +AGRLRLDEILTIRAEDLSPWSPIADAWPGRAYSVQELLAAAVGDSDNTAADLLMKHIGGP +GVVSAWLQSKGITEVRVDRYEREVQPAYMADPRDSATPEGMLGLLRRLDQDELVSPASTR +RLLTLMVQTPRGGDRIKAGLPKTATFAHKPGTSGNAAFNDVGIFTLADRRSYAVAAFLTG +STATDAERAALFADLGRTAA--- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Taibaiella sp. F-4 TaxID=2301235 RepID=UPI000E573020 +-eALRQSLQGIVDTARAHIGVGVLDLDTGDKL-LINGNDSFPMQSVFKFPLAIAVLHQME +QEKKPLSTPVSLSRKNMEAWSPMLRDHKEEQITLGELLSYSVKKSDNNACDALFRLADGT +LVVDQYIKSLGIKGMAIKATEAEMRMAWPVQYTNSCRPDAMLQLLQQFYRKKLLSPEHQQ +FLWQIMTDSENPADRIKGLLPAQAVVTHKTGTSDTAATNDVGIISLPNGRHIALVVYVSD +FKGGTARGAHLIAIVAKAVWDHy +>[subseq from] class A beta-lactamase n=1 Tax=Francisella sp. SYW-2 TaxID=2610886 RepID=UPI00123DB259 +--TLDDSFKNLEDKHHGKLGIYTVNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM +QHKGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVKEIGGL +EKLNKLVTKLGDKDTIIKNDEPEINRTKPDSNINKTTPKAITQDIYNLAFGNILDKKHRE +IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQDKQPFALSVLYTN +PSVKALSNEKIIQQASKLIAD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chishuiella changwenlii TaxID=1434701 RepID=A0A1M7ALQ3_9FLAO +-nNLKEDLQQIISSKNATVGISIKEIETNDTL-SINGNLSAPLMSVFKFHIALTVLNEVD +KGKLKLNQKFFIKKADLHAWSPIQEKFPNGELTLDELIRYTVSHSDNNGCDILLNIIGGT +DVVQKFINEKGIKDFTIKVNEQQMSH-WENLYKNTTTPLASTELLEKFYKNKILKKNTTE +YLYQVMIETSRGITWMKAGLPKNTELAHRTGMSGTNAMNDIGIFKLPNGKHVILSVYLKE +ITESFEDTEKIIADITKAVWNYy +>[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium nitrogenifigens TaxID=1617283 RepID=A0A521CXB6_9FLAO +-nELRNQLQQIISSKSATLGVSVKGIENKDTL-SINGNLKMPMMSVFKFHIALAVLHKVD +EGKLNLTQEIFIKKKDLKEWSPMKVDYPEGNLTLDKILRYTVSHSDNNGCDILINLVGGT +NYIQKFINDQGIKDFVIKVNEDQMKT-WKNLYVNTTTPIATTELLEKFFKGEILKQETTK +YLYQIMVETSRGLTWMKAGLPENTELAHRTGISGTNAMNDIGIVKLPNGKHFILSVYLKD +ITEKREDTEKIIADVTKAVWDYf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000D1DA11F +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI000FD994F0 +-nHLHTELAALASAHPGRVGICVQDPTSPPIC--VNGEQRFSLQSVMKLVVAAAVMRAVD +ERRVALSDRVTVRREDLSVIQPIADIVSERGTSLGDLLRRAVVESDSAATDMLISRLGGT +KAIQAFLGGSGLHGIRIDRTERELQTAYLTDPRDTASPRGMVGFLHKLAAGQLLSASSTA +HLLEVMKKTVTFPDRLRAGVPSGWTIGHKTGTSRNGVTNDVGILTAPDGRHVAVAAFVAE +SRTGNEERAAMIAAAARAITAAy +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A0D5C9H5_ECOLX +---------------------------------------------------AAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDI------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter pelagi TaxID=994320 RepID=UPI001325ACCD +--RLEAQFRLIEVATGGTFGIAAYDTRADRMI-AYRGDERFALASTFKASLAAFAMTEAQ +AGRIDLDERTFWTQADFVFHRPFTGERVDSGATWRELAYAAQTQSDNVAANLLLKRLGGP +EALTAFWRSLGDPVSRLDRFETDLNRVPPGTVEDTTTPATMARTLATLLFAEPLVPERRQ +ELRRWMAESVTGLQKIRAGLPRGWEAGDKTGNSSPQVRGDIGFVIGPLDAPVTFAAYHRS +PLLDDAPVDAGFAAIGRA----- +>[subseq from] class A beta-lactamase n=1 Tax=Francisella sp. XLW-1 TaxID=2610887 RepID=UPI00123CC7A1 +--TIDDSFNNLEDKYHGKLGIYTVNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM +QDKGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL +ENLNKLVTKLGDKDTIIKNDEPKINHTKPDSNINKTTPKAITQDIYNLAFGNILDKKHRE +IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQDKQPFALSVLYTN +PSVKAPSNEKIIQQASKLVAD-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium polynesiense TaxID=1325933 RepID=UPI00058C5FA2 +---LENEIKNFISNEKGRISVAVKNLKTGETI-KINENEVFPSASTIKLVIMSELLKNVK +EGRLKLKDTVEITKEDITGGDGIIKENLNHKFTLEELMTLMIIISDNTATNILINLL-GI +DKINAMAESLNMKNTKLQRKMMDLEAA-KEGKENKTTAEDLANILELIYTGKNISEEYSL +MMLNILKRQQV-KGRLDLYLPEEVTIAHKTGDLDK-LEHDVGIVFLKDSD-YIICVLTKD +TD-TNKDGREIIGKISKMVYDEf +>[subseq from] Uncharacterized protein n=2 Tax=Flavobacterium rivuli TaxID=498301 RepID=A0A0A2M2D4_9FLAO +-tELREQLEKIVADKKATVGISVLGLEDGDTL-SMNGDRNFPMMSIFKFHIALTVLKKVD +NGALSLKQKIFISSKELLDWSPIKDKYPAGNLTLDEILMYTVSHSDNNGCDVLLRLIGGT +QVVQEYINTLNIGSFVIRYNEEQMASG-ELAKVNTTTPLATTKLLSLFYNYKLLEKKTTR +YLNELMEQNSRGKALIKGKLPTGTKVAHRTGMSGTDALNDVGIITLPNGKHYAVAIYLNN +ITENKETAEGLIADVSKSVWDYf +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A127SLQ7_9BACT +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYSNWSTPSEMVRLLKMADEKNLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGIVIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. LASN5T TaxID=2491021 RepID=A0A3N9RS16_9SPHN +---IQQQIAAIASQSRGRIGVAAMDLDGGGQI-FLNGDMPFPMASTAKIAVAATFLEGVE +QGRFRLDQRFPMMLSVAERRSPIAPVRAGPVMTAQELMELMITRSNNQATDGIIAAIGGI +APVNQWLTRKGIVGQRLDHTMATLVRATVIDTRTSSTPRAMLALLAAIDRGGALNPESRA +VLLDTMTRTSTGRNRIRAGLPEGTLVAHKTGTLA-GVTDDVGIVRLPDGRHLAMVVFVAG +PEG-HAPQSALIAQVARVLYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Agromyces subbeticus TaxID=293890 RepID=UPI0003B77BF3 +--RMNEALRALEQSNAVTIGVTALVHGSRHAF-RYRGNELFPMCSLFKSLAAAALVQARG +YDEVYWSTPIPFTIADRVGDSTKLNT--DTWATPEELADAAIRYSDNTAGNLLLRELGGT +QAVTTFARSLGAQRTRLDRAEPEVNEALPGDERDTSTPDDIAFLFELLMLDHGAGALTGA +RLQEWMLRNTTSGRRILAGLTPPFELADKTGLGGYGVVNDAGIVWRPGEAPVTLAIMTRT +DRADAPNNQDVLAEVTRIVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. Mgbs1 TaxID=2485489 RepID=A0A433WLE2_9BACT +-----RAYATIASGIKGTVGISSVVLETGAAA-GLRTNEHFPMQSVYKFPIAMAVLHEVD +KGRLSLQQPVRVLPSDLIPHSPLRDAHPAGNYSIAELLRLNVAESDGTACDVLLRLLGGP +EKAGQYVHSLGITDISIATTEQVQVPDEMVQYRNWSTPAAMTALLRKFYTGKLLSDSSYH +FLLHLMVTSTPGAKRLKGLLPKDAIVAHKTGTSGTRATNDAGIITLPNGHHLLISVFVKD +ARADLAQREATIARIAEATWKAy +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WKG3_9BACT +--KLERQIAAIAPLSGGTVGVAATHLESGRSV-FVNADDQFPLASTYKVPIAIQAFKLVE +EGKLSLDQMVPVLPTDIHIGSEWNKLFQAPGLSFRNVIEPMLIFSENSATDLALRLVGGG +EAVTARLRALGINDMRIDRSTADVIAYYANDPRDHGSPRAMLTILTRLWKGELLNKANTA +YMLDIMYRCETGQGRIKGMLPPGTRVAHKTGTFP-GTTNDVGVIDLPDGTHVAIAVYIKK +SSVPGADLEATIAQVSRAAYDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A649VYG8_ECOLX +------------------------------------------------------------ +-----------IKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLI------- +----------------------- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Porphyromonas macacae TaxID=28115 RepID=UPI001269F717 +--RLKSEINRLIKDKNATVGVSIIANNRKDTI-GINENLHYPMQSVFKLPIALTVLSEVD +KGALRLEQEIRISSTDLLSWSPIRNKYPKGTMPLSEVIRYTISESDNNGCDILLQLIGGT +TAVEEFLSKYELTDISIKASEKEMHETPDLQFRNRATPVSLTKLLTMFYGKSILSQKSFD +FLWKVMVDTSTGGNRLKGQLPEGTRVAHKTGTSGIAATHDIGIIILPTGDPVFISILVSN +STEDIKTNEKIISDIARKVWEYy +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8Q1W2_9BACT +--SVKQEVVNAAKASGGEMGFAASHIETGRRL-TLNSSGRFPMASAYKLPIAIQMLTLVD +EGKAQLERIIKIEPKDIRPGVPLTDKFNAESVSVGDLLEMMLTVSDNTASDLILRLAAGP +EAVTARMRSLGIEDMSIDRSTIEHVFQYGRDLRDTSTPDAMASLLVHVYRKNLLKPETVK +LLLGIMRRCQTGDTRLKGLLPAGTELAHKTGTAM-GIINDVGIITLPNGGHIAIVVFIKG +SKSSVAECEHSIAEVARSAYDYf +>[subseq from] Beta-lactamase n=2 Tax=Porphyromonas macacae TaxID=28115 RepID=A0A0A2E3C2_9PORP +--RLKSEINRLIKDKNATVGVSIIANNRKDTI-GINENLHYPMQSVFKLPIALTVLSEVD +KGALRLEQEIRISSTDLLPWSPIRNKYPKGTMPLSEVIRYTVSESDNNGCDILLQLIGGT +TAVEKFLSKYELTDISIKASEKEMHETPDLQFRNRATPVSLTKLLTMFYGKSILSQKSFD +FLWKVMVDTSTGGNRLKGQLPKGTRVAHKTGTSGIAATHDIGIIILPTGDPVFISILVSN +SAEDIKTNEKIISDIARKVWEYy +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium taichungense TaxID=295069 RepID=A0A1H8CLF9_9FLAO +---LEQKIDSIIQDKNATVGISVLGFEDGFKY-YKNADKRLPMQSVFKFHIAVALLNYVD +KGKLSLDQKVLLDKTNLFEWSPLRDKYPDGVVPLSEILEYTVAKSDNNGCDIILKLLGGT +QTVQRFMDSKGVKGFQIKYNEAEMRKDWNIQYKNYSTAASATDVLKKFYDGKLISRKSTD +YLMQIMFSTSTGKNKLIEQLPENTPVARKTGASGTGAENEIGIVTLPNGKHYAIAVFVSN +STETNVVNCKMISDISKSVWDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6BIN7_9BACT +------------------------------------------------------------ +---------------------PVTKEHLKEGMTLGGLCAAAIEQSDNTAANLLLDAIGGP +AGLTNLARNLGDNATRLDRKEPELNSAIPGDERDTTTPGAICSDMQRLLLGDALSEASRR +QLEDWLQHNETGEQMIRAGVPNNWIIGDKTGRGSNGATNDIAIMRPPDRAPILLAIYSVG +STATANDREEAIAEAAKIVAETf +>[subseq from] Beta-lactamase n=1 Tax=Akkermansia sp. CAG:344 TaxID=1262691 RepID=R7E586_9BACT +-----AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD +QGALNLEQIIHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT +ETVQKDLKEWGISGINIRFTEDEMLRNHELQYANSSRPSAMNALLRAFDEGKILNKDTQR +LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD +SKDSAPACEKVIASMARWLCTEw +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. SLB01 TaxID=2665645 RepID=A0A5Q3R0B2_9FLAO +-nELRQQLNQIISSKNATVGISIKGIEDKDTL-SINGNLKAPMMSVFKFHIALAVLNKVD +EGKLSLTQEIFIKKKDLHEWSPMREDYPDGNLTLDKVLRYTVSHSDNNGCDILIDLVGGT +KVIQKFINQQGIKDFVIKVNEDQMKT-WKNLYVNTTTPLATTTLLEKFFKGEILKESTTK +YLYQIMTETSRGLTWMKAGLPENTELAHRTGISGTNAMNDIGIVKLPNGKHFILSVYLKN +IIEKQEDTEKIIADITKATWHYf +>[subseq from] Class A beta-lactamase n=1 Tax=Alphaproteobacteria bacterium HGW-Alphaproteobacteria-14 TaxID=2013660 RepID=A0A2N3DBB8_9PROT +--RLAAELRLIEAAAGGTLGVEIYNTVSGQSV-GINRDRRFGHASSFKLSLAAMVLARHA +AGTIDADRRVTWGEADMIAHAPFTRERIGSGATLRELARATQITGDNPAANILLRALGGP +AALTAFWRSIGDDVSRLDRIEPELNFVPAAEFRDTTTPAAMARTVAKIVYGEVLPEAERA +ELRQWLIATETGLRRVRAGLPEGWIAGDKTGTSLGSLYVDIGIAEGPKGPPITFAAYFVA +REHDDPAAELALSRIGKVIAE-- +>[subseq from] Serine hydrolase n=1 Tax=Sinorhizobium sp. M4_45 TaxID=2037901 RepID=A0A2N8JRJ3_9RHIZ +--RLRLELETLADAHPGRVGICVQD-QPKSPV-CVNGAQRFSLQSVMKLVVAAAVMQAVD +EQRIRLDDQITIRREDLSVIQPIADIVARHGTSVRDLVRRAVVASDSAATDVLIARLGGT +KAIQAFLEKAGLTGVRIDRTERELQTAYIKDPRDTATPRGMAAFLYSLASGSLLTAGSTE +FLLTVMSQTTTFPDRLRAGIPPEWGIGHKTGTSQNGVTNDVGILTAPDGRRIAVAAFVAE +SRAGQAERAAVIAAAARAITAAy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. ACN6 TaxID=1920426 RepID=UPI000BB37870 +--DLRKNIEQIIASKNATVGVSMKGIEDKDTL-SINGTLNAPMMSVFKFHIALTVLNQVD +NGILKLDQKFFIKKEELLPWSPMREEFPDGNFTLDQLLRYTVSHSDNNGCDILLRIIGGT +QTVQKFINKQGITDFVIKVNEQEMS-IWENLYLNTTTPLATTELLEKFYKGQILKKATTK +YLYQLMVETSRGKTWMKAGLPANTELAHRTGVSGTNAMNDIGIVKLPNGKHFILSIYLKN +ITEEMEDTEKIIAAITKAVWDY- +>[subseq from] D-alanyl-D-alanine carboxypeptidase n=1 Tax=Bythopirellula goksoyri TaxID=1400387 RepID=A0A5B9QFY6_9BACT +-eDLSSRIQPLIDAFDGEVGVMVKQLETGETF-EYSSTVPMPTASLIKLPIMIATYKAID +SGKLDLAQKITLKAEDKVPGSGILAEHFSDGLPLKDAIHLMIVYSDNTATNLVIDQV-GL +PRTTEVMKELGCDETVLNSKVFRRDTRSKKYGLGSTTAKEMVSLLEKLQAGQLLSKQASK +QMLAHLRACND-KTKFSRLLPPEIVVAHKTGSVSD-SRTDAGIIESPGG-PIALCVLTTN +IANDDNAAELLCSNIAKAAYDYf +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sediminis TaxID=1679494 RepID=A0A5B2UC15_9FLAO +---LEQKIHSILKNKKATVGVSVLGFENSFKY-DKNSDKKLPMQSVFKFHIAAAILNSVD +QGKLSLDQKIVLNQSNLLEWSPLRDKYTGSNIPLSEVIEYTVAKSDNNGCDILLKLLGGT +QPVQKFMDSKGVKGFQIKYNEEAMHKDWKVQYENYSTTKSAVDVLKKFYDGKLLSKKSTD +YLMQVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN +SMETDAVNCRMVSDISKEVWEYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SHS7_9BACT +-qTLEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REKIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYYNWSTPSEMVRLLKMADEKDLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter sp. GH3-15 TaxID=2545755 RepID=UPI0010F62AEB +---LARQIAQLADGSQGRIGVAALDLSTGREI-SILGDQRFPMASTSKIAIAAAYMEGVE +QGKWSLTSEFPLLWSVRSTFSTAAAPVRKGELSAHQLIDLMLTRSSNPATDALLAAVGGP +DAVNDWVHRAGLQDFELTRDIATLVRARHIDTRDSATPETMVQLLTGLYQGRWLSAESRE +VILDAMARCRTGVRRIRGQMPNDVSVAHKTGSLHN-TSSDIGIITAPDGRSYVVAIYVTG +QG-SRGNREQRIASIARAIYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium sp. B 225 TaxID=1961849 RepID=UPI000B4BE8B8 +---LEAQIASLAAPAQGRIGVAALDLSTGRTV-SVLGNQPFPLASTSKVAIAATFLAGVD +QGRFRLSDQYPLMVPVRSAYSEVAPVRAGATMSAQGLIELAITRSDNPAADALLAAVGGP +QAVNRWLQGAGLSGMRMDRDIATLVRATTIDPRDSATPLTMVELLGGLYRGQWLSSSSRN +LLLGTMARTVTGKRRMRALLPGEAGIAHKTGTLSN-TASDVGIITTPDGRSIAVAIYVTG +QG-SKAGRDARIASIARAIYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Sphingorhabdus sp. EL138 TaxID=2073156 RepID=UPI000D68C483 +--AARRELAKLEKRIGGRLGVALTDAKGDIAL-DHRGDERFAMCSTFKAPLAFALFDAAD +KGRVDVKKSFAVTENDLVPYAPFVEEQIAAKVTLEQLAKATVKSSDNAAANLILKAIGGP +EAFTDFVRRRGDVITRLDRIEPFLNENKVGDPRDTTSPIAFAKLMHGMMSGKS-RLTNWS +IVYDAMASSKTGLGRIRLGLPYGWPVGNKTGTAGGGAYNDVAIFWPSGDEPRFLTVYTDR +PTASAAIVDRTIAEVAKIA---- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000B498344 +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDLLTIRRDDLSVIQPIADIVAERGTSVGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Class A beta-lactamase n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A2E5I532_9BACT +---LALELTRLGELSGGTMGVGVIHIESGRRV-YVNNNERYPMASTYKVPIAVQLLKRVQ +MKEITLDQMVEVQTYDLHPGSGTLSRFINPGLSVRNLLELMMLISDNSATDIMLDTAGGS +KRVNRILKTNGISGMNVDRSTVRLIAVFSRDKQDTSTPEAMAVLLEKIWNKEILNPEMSE +LLIDIMGRCKTGEDRLKGMLPEETFVAHKTGTIGS-TTNDVGIIELPNKGHVVVAAFVKD +SELEIPERERAIAHAARAAHDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. OV279 TaxID=1500285 RepID=A0A1M4XKL6_9FLAO +--NLRQELKQIISAKNATVGISIKSIEDKDTL-SINGHLNAPMMSVFKFHIALATLNLVD +KGKISLAQKVFIKKEDLQQWSPIKDEYPNGNLTIDQLLRYTVSHSDNNGCDILLKLIGGP +ETVQKFINRQGIKDFVIKVNEEEMR-IWKNLYINTTTPLATTDLLEKFYKGKVLKKATTQ +YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISSRAAMNDVGIVKLPNGKHFIISIYLKN +ITEKREDTEKIIADLTKATWN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDAF38F +-dRLRSELTVLANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] VEB-PER_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WZ77_9BACT +--ALVTRLSKLLGPLQPKVGVSVKLAGKQQTS-GWNESAHLPMQSVFKFPIAVVVLSEVD +KGNLSLDQEIDIQKKDLPAWSPIRDDHPSGALTLAEILQYTVSQSDNIGCDLLLKLLGGL +EKVQHYFATHGFTEISVEVTEDDMHRDWNAQFKNWCTPREITRIIEATYEDRLLSESSHA +FLWKIMTETNTGQKRLKALLPADAIVSHKTGSSGTAGTNDVGVIQLPNGRAVYISVFVTD +SKESDEVNERIIAEIGKLVWDYy +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI00047FD84A +-dRLRSELTVLANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDQAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium 32-64-22 TaxID=1970593 RepID=A0A258GS62_9SPHN +---LAQQIARLADGSAGRIGVAALDLSTGREI-SVLGDQRFPMASTSKIAIAATYMEGVE +QGKWSLTSEFPLLWSVRSTFSTSTAPVRKGEMSALQLIDLMLTRSSNPATDALLAAVGGP +DAVNDWVRRAGLEDFELTRDIATLVRAQHIDMRDSATPETMVELLTGLYQGRWLSAESRE +VILDAMARCRTGVRRIRGQMPDDVSVAHKTGSLNN-TSSDIGIITAPDGRSYVVAIYVTG +QG-SRGNREQRIASIARAIYDGy +>[subseq from] Beta-lactamase n=2 Tax=Porphyromonas macacae TaxID=28115 RepID=A0A379E6T7_9PORP +--RLKSEINRLIKDKNATVGVSIIANNRKDTI-GINENLHYPMQSVFKLPIALTVLSEVD +KGALRLEQEIRISSTDLLPWSPIRNKYPKGTMPLSEVIRYTVSESDNNGCDILLQLIGGT +TAVEEFLSKYELTDISIKASEKEMHETPDLQFRNRATPVSLTKLLTMFYGKSILSQKSFD +FLWKVMVDTSTGGNRLKGQLPKGTRVAHKTGTSGIAATHDIGIIILPTGDPVFISILVSN +SAEDIKTNEKIISDIARKVWEYy +>[subseq from] Beta-lactamase n=2 Tax=Porphyromonas macacae TaxID=28115 RepID=A0A379DF02_9PORP +--RLKSEINRLIKDKNATVGVSIIANNRKDTI-GINENLHYPMQSVFKLPIALTVLSEVD +KGALRLEQEIRISSTDLLPWSPIRNKYPKGTMPLSEVIRYTVSESDNNGCDILLQLIGGT +TAVEKFLSKYELTDISIKASEKEMHETPDLQFRNRATPVSLTKLLTMFYGKSILSQKSFD +FLWKVMVDTSTGGNRLKGQLPEGTRVAHKTGTSGIAATHDIGIIILPTGDPVFISILVSN +SAEDIKTNEKIISDIARKVWEYy +>[subseq from] Beta-lactamase n=1 Tax=Francisella hispaniensis FSC454 TaxID=1088883 RepID=A0A153JBJ7_9GAMM +--QLHDSFKSLENKYDGKIGIFTVDTDNKTNI-KYNENYHFPICSVFKFLLVGAVLDYDM +HNQGFLDKKIPITQDDIGTYAPITAKNIDKSLTISQLNYAAI-LSDNPAANILVREIGGL +QNLNKFIKKLGDKDTIIIADEPKVNHTKPDSNINKTTPKAITKDIYKLAFGNVLDKKHKD +IFIKYLEDNNTGANRIAFSMPKDWIIGDKTGTCGYAATNDVAIIWPKNRQPIGLGILYTN +PNKNAPSNEEIIQQAAKLIAN-- +>[subseq from] serine hydrolase n=1 Tax=Qipengyuania sediminis TaxID=1532023 RepID=UPI00105A3556 +-sALAQRVAELANASAGRIGVAALDLTTGETV-GVLADQRFPLASTSKIAVAATFLEGVE +QGRWRLDQAFPLLHPTASRFSTSTAPVVAGQLPARELIEQMIVRSSNPATDALLRVVGGP +KAVNAWMRRAGIRDFSIDRDIATLVRAHHIDRRDSATPNAMVQLLAGIYQGKLVAPASRQ +VILGAMSRTVTGKRRIRALIPAGARVLHKTGTLS-GTASDIGFIETPEGHTLAIAIYVTG +QG-TKPARDAKIAAIARGLYDGy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. LC2016-13 TaxID=2675875 RepID=UPI0012B8208B +-sQLREQLNEIIASKNATVGISIKSIEDKDTL-SINGKLKAPLMSVFKFHIALAVLNKID +EGRLSLTQEIFIKKKDLHEWSLMREEYPNGNLTLDKLLRYTVSHSDNNGCDILINLVGGP +KEIQKFINKQGIKDFVIKVNEEQMKT-WKNLYINTTTPLATTELLEKFFKGEILKENTTK +YLYQIMVETSRGVTWMKAGLPETTELAHRTGMSGRAAMNDVGIVKLPNGKHFILSVYLKD +ITEKQEDTEKIIADITKATWDYf +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. CECT 9293 TaxID=2675057 RepID=UPI00135E4827 +---LHDKINIILLNKNATVGVSVLGFENGFTY-NRNADKKLPMQSVFKFHIAAAVLDFVD +KGKLSLNQKVLLNSSNLLEWSPLRDKYPNGGVPLSEILEFTVAKSDNNGCDIMLKLLGGT +ATVQKFMDSKGVKGFQIKNSEAEMHKDWKLQYKNFSTTQSAVDVLKKFYDGKLLSKKSTD +YLMKVMLSTSTGMNKLVEQLPKNTPAARKTGASGTGAENEIAIITLPNGKHYAIAVFVSN +STESDKVNCKIISDISKVVWDHf +>[subseq from] Beta-lactamase class A n=1 Tax=Bosea sp. OK403 TaxID=1855286 RepID=A0A1I3RTK1_9BRAD +-tRLDQEIAAIERQSQGRLGVALLDLKDRKSW-SHRGSETFPMQSVFKLPLAVAVLQAVE +AGKLKLDQPITITRKDFSLHSPLAKAFTGESYPLRELIALAAGESDNTAADNLMRLIGGP +QVVTKMLRDGGIGGISVDRYEREFQPLALKDPRDAATPEASTLFLEALAKGNWLRDPAHA +FLDTVITETKSGPLRIRAGLPLGARFAHKTGAGLNHATNDIGIVTLPNGHVFAIAIYLAG +SKADEKGREAAHAAVAKAAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Francisella marina TaxID=2249302 RepID=A0A5C2BWM0_9GAMM +--TLDDSFKNLEDKHHGKLGIYTVNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM +QHKGFLDKQILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL +ENLNKLVAKLGDKDTIIKNDEPKINHTKPDSNINKTTPKAITQDIYNLAFGNILDKKHRE +IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAASNDVAIIWPQDKQPFALSVLYTN +PSVKAPSNEKIIQQASKLIAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Porphyrobacter sp. AAP82 TaxID=1248917 RepID=UPI000307F6BD +---LAAELRIIEAAGGGTLGVEILDTATGMSV-GINQDHRFGHASSFKLSLAALLLQRHA +AGTIDADRRVMWTEAEMLNPAPFTRARIAQGASLRELARATQTTSDNPAANILLRELGGP +AGLTAFWRSLGDAVSRADRFEPDNNLVPTGEFRDTTTPAAMARTVAKIVYGDALPAKERA +ELKGWMVETQTGLKRVRAGLPEGWIAGDKTGTSGY-NYIDIGFAEGPKGGPLTFACYFRA +RQEMLASGQETLARVGRIITE-- +>[subseq from] Beta-lactamase n=2 Tax=Novosphingobium malaysiense TaxID=1348853 RepID=A0A0B1ZF81_9SPHN +---LGQQLASVAEASQGRIGVAAIDLATGREL-DVLGDQRFPMASTSKVAIAATFLEGVD +KGKWSLTSEFPLMIPVSSASTPVAPVRPGAYMSAERLMELMLTRSNNYATDALLKVVGGP +SAVNEWVRRAGIEDWHIDRDIATLVRAQVIDKRDSATPMAMVKLLSGLYQGKWLSPSSRK +ILLDTMSRCVTGKRRIRAGLPDDVQLLHKTGSLHN-TSSDIGIVETADGRVFAVAIYVTG +QG-SRPAREARIARIARTLYDGy +>[subseq from] Beta-lactamase n=1 Tax=Mucilaginibacter corticis TaxID=2597670 RepID=A0A556MI75_9SPHI +---LQAKIGQCAKNANGNVGVYALVLETGETV-SYNGDKKFPMQSVYKFPIAMAVLDRVD +KKQLSLNKKISVTKADYIAHSPLRDKFPNGTIAIKDLVKYSVSESDGSASDVLVRLLGGT +KFANEYVHRLGVKDIAIATTEKIQVENDTIQYQNWATPKAMTSLLNIFYTRHKLSASSRA +VLLNDMITSTPGAKRLKGLLPVGTIVAHKTGTAGTRATNDAGIITLPNGKHLAITVFIAD +SHSSEEIRELTIAKIGKAAFDYw +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. TaxID=1874826 RepID=A0A519QGM9_9SPHN +---FEAQVAALANAQGGRIGVAALDLSTGRSV-AVLGNQPFPMASTSKVAIVATFLEGVD +QGRFRLEDQYPLMIPVPSRDGPVAPVRAGGMYSALNLIEMTITRSDNNATDALLAVVGGP +QAVNRWLRKSGLNDLHIDRDIATLVRARTVDTRDAATPLAMVRLLSGIYRGEWLSASSRA +VLMGAMERCLTGKRRMRALLPEDARVAHKTGTLYN-TSSDVGFIHMPDGRPIAVAIYVTG +QG-GKPNRDARIAAIARALYDGy +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter gangjinensis TaxID=502682 RepID=A0A0G9MM20_9SPHN +--QLEMVISQLAEGSQGRIGVAAIDLSTGQQI-SVNGDMRFPLASTSKIAIAAAYLEGVD +QGRWSLTAEYPLLWPVRSEPLSTRAAPVRAGMPAHELIDIMITRSSNPATDALLAAMGGV +EPVNDWMRRAGITEFSLDRDIATLVRRTYIDPRDSATPEAMVQLLAGLYQGRWLSAQSRN +IIIDAMERCRTGRSRIPARMPEGVTVAHKTGTLHR-VASDIGILTGPDGRSIAVAIYVTG +QP-SPAERNGRIASIARALYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI001295E52E +--RIRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVLAAAVMQAVD +DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SZE9_9BACT +-sELENRIDSLLNGKKATVCIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMAQLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD +SYETDEDNADIIARISRMVYDA- +>[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI000FD85EBE +-nHLHTELAALASAHPGRVGICVQDPTSPPIC--VNGEQRFSLQSVMKLVVAAAVMRAVD +ERRVALSDRVTVRREDLSVIQPIADIVSERGTSLGDLLRRAVVESDSAATDMLISRLGGT +KAIQAFLGESGLHGIRIDRTERELQTAYLTDPRDTASPRGMVGFLHKLAAGQLLSASSTA +HLLEVMKKTVTFPDRLRAGVPSGWTIGHKTGTSRNGVTNDVGILTAPDGRHVAVAAFVAE +SRTGNEGRAAMIAAAARAITAAy +>[subseq from] Class A beta-lactamase n=1 Tax=Cryobacterium sp. Sr39 TaxID=1259198 RepID=A0A4R9ALB5_9MICO +-----RSVRQLESTSGVMIALSAKNVRSGRQI-NHRATEPVPMCSLFKVLAVANLLRLRG +YEDQYWSTPISFTAADVVVNSPVAAASTSMTMTPNQMADAALRFSDNTAGNLLLRELGGP +ATITQFAQALGARRTRLDRIEPELNEGLPGDVRDTTTAEDMVAIMEALLIDGDAGQLARS +RLQDLMLRNTTSGTRARAGLSEPFELADKTGAGNYGIVNDAGVLWQGQRQTIAMCILTRT +EVASAPNNNDVIADATRLIVSEf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=A0A412DEK7_BACSE +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYANWSTPSEMVRLLKMADEKNLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVITPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD9E559 +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGSRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas sp. NS26 TaxID=2293980 RepID=UPI000F03535B +-------LSALEARHGGRIGFRLQG--PSGDV-GWRAEERFLYCSTFKLFLAAATLNRVD +RGEERLDRAVPITAEDITPHAPATEPAVGSTLTIETLCQAAVEVSDNPAANILIRELSGL +DAWRGWYRSIGDETTRVDRLETELNT--PDGDKDTTTPAQVVRNLQRLFVGGGVG-AHRD +LLTQWLTDTPTGAGRIKAGVPAGWTVAHKTGTGE-GPTGDIGLIWNADGGLMLVAAYYDA +PEATPEQRDAVIADAMRA----- +>[subseq from] class A beta-lactamase n=1 Tax=Citromicrobium sp. JLT1363 TaxID=517722 RepID=UPI000225DF01 +--RARAQLVDIEKRSGGRLGVALIDPAGAVLL-SHRGEERFAMCSTFKTLLAGMVLSGVN +--GLEPEDRLIIDPAAVEGHAPFTRSRFEEGMTVGDAAKNIVTVSDNGAANLLLDEVGGP +RGLTEWIRALGDDVTRLDRRELALNENAAGDPRDTTSPLAFGETYRRVLSDDVLDAADRD +QLARWLVASETGLNRLRAGIPGDWSVGDKTGYCAAVEINDVAIFDPAGGGWYTLVFFLDR +PREAGAFADALGAEVGAIAAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Ensifer sp. USDA 6670 TaxID=936134 RepID=UPI00040377CA +--SLRAELAALASAHPGRVGICVQD-ETSRPI-CVNGEQRFSLQSVMKLVVAAAVMQAVD +EGRIALGDRFTIRREDLSVIQPIADIVAIKGTNVRGLVRRSVVESDSAATDVLISHLGGT +KAVQAFLDSAGLRDIRIDRTERELQTTYLTDPRDTATPRDMVGFLHRLATGELLSVSSSA +YLLEVMNGTVTFPDRLRAGVPSGWMIGHKTGTSQNGVTNDVGILTAPDSSHIAVAAFVAE +SRAGKDERAAMIAAAARAITAAy +>[subseq from] Class A beta-lactamase n=1 Tax=Erythrobacter sp. JBTF-M21 TaxID=2584124 RepID=A0A547PCK1_9SPHN +---LTAKLRIAEAAANGMLGAEIYDTATGYCV-GLNRDRRFGHCSSFKLSLAAMVLARNA +AGQDSLDRRVTWTRDALMSVSPFTTERLGEGATLLELAEAVQKFSDNAAANILLREVGGP +QAMTGFWRSIGDETSRLDRMEPALNNVPITEVRDTTTPSAMARTVAKIAFGDVLPASEQS +MLRQWMTDTSTGMRRVRAGLPDEWRSGDKTGTSIGSLYVDIGFVEPEKHPPITFATYFRA +RETHDPTSETALARVGEIIAD-- +>[subseq from] Beta-lactamase CTX-M (Fragment) n=1 Tax=Escherichia fergusonii TaxID=564 RepID=A0A679G483_ESCFE +-------------------------------------------------MAAAAVLKKSX +XEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTXNDI------------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. 52 TaxID=2035213 RepID=A0A2G6UNF4_9FLAO +-qQLRNELQEVISTKKATFGISMKGIEDKDTL-SINGTMKMPMMSVFKFHIALAVLDQVD +KGKLQLNQKFFIKKEELHPWSPIKDEFPEGNLTLDQLLRYTVSHSDNNGCDLLLNILGGT +QTVQKFINKIGIKDFTIKVNEHEMTGE--NLYANTTTPIATTELLEKFYRGKVLKKVTTK +YLYKIMVETSRGITWMKAGLPEGTELAHRTGISGRAAMNDIGIVKLPNGKHFILSIYLKN +ISEERVATEKIIADITKAVWEYy +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A0M2NW81_STACC +---AAKSFDQIEQDNDTIVGVYGINTANGKVI-QHRSDERFAFASTYKAISSGILLQNTS +--TSELNKKITISKDDIVAYSPATEKYVGKQMTLRALIKASILQSDNTANNKIIEEIGGI +KGFQQALKQRGDNISNPQRLEPDLNLYDPQSTADTTTPKRAATTLNHLLASENMSRSNLE +LLKHTMIHNETGDTLIKAGASKDDVVGDKSGQGTYASRNDLAFVYPENQKPIILAIYTKK +TDKDAKPDDKVIQTAAETAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI000D1C253A +---AAKSFDQIEQDNDTIVGVYGINTSNGKVI-QHRSDERFAFASTYKAISSGILLQNTP +--TSELNKKIAISKDDIVAYSPVTEKYVGKQMTLRALIKASMLQSDNTANNKIIEEIGGI +KGFQQALKQRGDNISNPQRLEPDLNLYDPQSTADTTTPKMAATTLNHLLASENMSRPNLE +LLKHTMIHNETGDTLIKAGASKDDVVGDKSGQGTYGSRNDLAFVYPENQKPIILAIYTKK +TDKDAKPDDKVIQTAAEKAIK-- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Mucilaginibacter ginsenosidivorax TaxID=862126 RepID=A0A5B8W8J4_9SPHI +---LKAKIDEIAKDAKGTVGVSVLNLETGDTL-NYNGYLHQPMQSVMKFPIAITVLHEID +EGKFTLDQQLRLDKSDLFKYSPLQDKYPAANVSIRELLSYMVSLSDNVACDKLLKILGGT +DVVDTYIHHIGIKNFSIKASEYQMAQAWDVQFSDWVMASELTHLLNVAFKPNFLSTASHA +YLWKIMQETSTGPNQIKGLLPVGTIVYHKTGRSGTNATNDTGIITLPNGNHLAIAILVTN +SPVDLKTRESVIARIAKAAYD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=A0A413E128_BACSE +-qTLEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REKIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYYNWSTPSEMVRLLKMADEKDLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD +SSETDEKNAAIIAHISRMVYDE- +>[subseq from] Beta-lactamase n=2 Tax=Francisella novicida TaxID=264 RepID=A0Q6U4_FRATN +---LNDSFKSLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM +HNQGFLDKKIPITQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDNPAANILVRELGGL +QSLDKFIKKLGDNDTIITADEPEVNYTQPHSNINKTTPKAITKDIYKLAFGNILDKKHKD +IFIKYLQDNNTGTNRIAFSMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN +PNKNAPSNEEIIQQAAKLIAN-- +>[subseq from] FTU family class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI000158B0AB +---LNDSFKSLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM +HNQGFLDKKIPITQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDNPAANILVRELGGL +QSLDKFIKKLGDNDTIITADEPEVNYTQPHSNINKTTPKAITKDIYKLAFGNILDKKHKD +IFIKYLQDNNTGTNRIAFSMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN +PNKNAPSNEEIIQQAAKLIAN-- +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter epoxidivorans TaxID=361183 RepID=A0A0M3T9N4_9SPHN +---INAKLRIIEAASGGTLGVAMYKTLTGATA-GLNRFERFGHCSSFKLSLAAMLLSKDA +SGAIDAEELVRWTKDDLLSHAPFTTERLGQGATLRELARAAQVLSDNTATNLLLQRLGGP +EGMTAFWREIGDVSSRLDRMEPELNNVPAGEVRDTTTPDSMVRTVARLLFGNVLDRDNRA +TLLKWTVDTATGLQRVRAGLPSDWSAGDKTGTSHQPLYVDIGWVEPAGHPPTCFAVYHHT +KDETTTRANLVMQQVGEVIAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI00059B05C6 +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPDRLRSGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium oncorhynchi TaxID=741074 RepID=A0A316X1Z5_9FLAO +--ELKKIIESIIANKKADVGVSIMEVPQKEVV-QINGNKFYPMLSTVKFHIALAILHKVE +KGELSLQQKIYIKKDELLEWSPFQKEHPEGNLTLEETMKWMVSYSDNNLTDILLRLIGGP +EPVQKFINS---KNFVIKNNEEDMHKDWDSQFINTITPNEATRLLEKFYNGKLLNKEHTK +WLYTAMLNNASGAKRLKAHLPKSIKIAHRTGTSFTGAINDFGIIELSDKKRIYIAVFVHD +TYEKFENAEAIIADISKATYDYy +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium jejuense TaxID=445960 RepID=A0A2X2V9C5_9FLAO +-qDLRSKINTIISTKNTTVGISLKGIEDKDTL-SINGNKEMPMLSVFKFHIALAVLNQVD +KGKLKLDQKFFIKKEELLPWSPIREEYPEGNLTLDQLLRYTVSHSDNNGCDILIKIGGGA +PVVQKFINQQGIKDFTIRLNEQQMNTF-ESYFVNTSTPLATTDLLEKFYKGKVLKKETTK +YLYQIMVETSRGLTWMKAGFPAGTELAHRTGISGRAAMNDVGIVKLPNGKHFILSVYLKN +IHEEMKDTEKIIADIGNAVWEYy +>[subseq from] Beta-lactamase n=1 Tax=Francisella salina TaxID=573569 RepID=F8G6Z3_FRAST +--TIDDSFKNLEDKYHGKLGIYTVNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM +QHKGFLDKQILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL +ENLNKLVAKLGDKDTIIKNDEPEINRTKLDSDINKTTPKAITQDIYNLAFGNILDKKHRE +IFIRYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQDKQPFALSVLYTN +PSVKAPSNEKIIQQASKLIAD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Porphyrobacter sp. AAP60 TaxID=1523423 RepID=A0A0N1AZG7_9SPHN +--RLAAELRLIEAAGNGTLGVEIYDTASGMAV-GINRDRRFGHASSFKLSLAALLLQRHA +AGAINADKQVMWTEADMIAHAPFTRERIGSGASLRELARATQITSDNPAANILLKELGGP +AALTAFWRSIGDEASRLDRYEPEMNLVPTAEFRDTTTPAAMARTVAKLIYGDVLPEAERA +ELKGWMIATETGLRRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKGPPLTFACYFRA +RQTEA------------------ +>[subseq from] Beta-lactamase n=2 Tax=Chryseobacterium joostei TaxID=112234 RepID=A0A1N7JBJ2_9FLAO +--ELKKIIESIIVNKKADVGVSIMEIPKKEVV-QINGNKFYPMLSTVKFHIALAILHKVE +KGELSLQQKIYIKKEELLEWSPFQKEHPEGNLTLEETMKWMVSYSDNNLTDILLRLIGGP +EPVQKFINS---KNFVIKNNEEDMHKDWDSQFINTITPNEANRLLEKFYNGKLLNKEHTK +WLYTAMLNNASGAKRLKAHLPKGVKIAHRTGTSFTGAINDFGIIELSDKKRIYIAVFVHD +TYEKFENAEAIIADISKATYDYy +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter marensis TaxID=543877 RepID=A0A0G3X957_9SPHN +---FERRIAQAADGSDGRIGVAVLDLATGQEF-SILGDQRFPMASTSKIAIAATFMEGVE +QGRWSLSSEFPLLIPVRSERFSSAKARRGKHLPASELIELMITRSSNPATDALLAAVGGP +AAVNDWMRRAGITDFQLTRDIATLVRASAIDLRDSATPRAMTRLLAGLYQGEWLSPTSRR +VIIGAMERCRTGTRRIPALLPAGATVAHKTGSLNN-TSSDIGIINTPDGRAFAVAIYVTG +QG-TRLAREGRIAQIARAAYAGy +>[subseq from] Beta-lactamase n=2 Tax=Niabella ginsenosidivorans TaxID=1176587 RepID=A0A1A9HXV3_9BACT +-nTLQTQFEHISNDIKGHLGISALLIETGESI-QFNGNKKFPMQSVYKFPIAMAMLNQID +AGKFSLEDTIHIDKSQYIPHSPIRDKFPKGALTIKDIIRYNIEESDGTACDVLLRLLGGT +DKAQQHIHEWGVTAIAIATTEMVQVANDTIQYQNWATPEAMNKLLQLFFEGRCLSRNSRE +LLLQYMSISEWFDRRIKGLLPPGTKVAHKTGTAGTRATNDVGIITLPDGRHLAITVFIAD +SYDSQKDREMAIARVSRAAFDYw +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SHI8_9BACT +-qTLEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REKIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYYNWSTPSEMVRLLKMADEKDLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3D0MVD9_9BACT +-eKLRNEITEYLKGKDLKAGISFFSFSNGDTL-SINGDDFFPMQSVFKFHIGLAILNKAD +KGELNIEDKILIKKEDLKEWSPIREINPEGNLTIAELLSYSVSESDNNACDILIEIAGGT +EKIQKYFDDIGLKDFYIVANEYEMHQDWETQFRNKTTPKSSTEIIKKIYSDNLFSKKSFD +YLYKIMTETKTGQKRIKEQLPEGSIIGHKTGTSGKNAVNDIAFISLPNGFKYILSVYLTD +SKLDYPEAEKVMSDISKIISDYy +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. JM1 TaxID=1233950 RepID=A0A086ARE5_9FLAO +--DLSKELKQIISTKNATVGISIKNIEDKDTL-SINGHLDAPMMSVFKFHIALATLNLVD +KGKISLAQKVFIKKEDLQQWSPIKDEYPNGNLTIDQLLRYTVSHSDNNGCDILLKLIGGP +ETVQKFINRQGIKDFVIKVNEEEMR-IWKNLYINTTTPLATTDLLEKFYKGKVLKKATTQ +YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISSTNAMNDVGIVKLPNGKHFIISIYLKN +ITEKREDTEKIIADLTKATWN-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SNN1_9BACT +-----AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD +QGALNLEQIIHIRQEQLVKWSPLRERFPQGGFSLKELLRVTVKESDNNTCDLLFALIGGT +ETVQKDLKEWGISGINVRFTEDEMLRNHDLQYANSSRPSAMNALLRAFDEGKILNKDTQR +LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD +SKDSAPACEKVIASMARWLCTEw +>[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI000462BC01 +-nHLHTELAALASAHPGRVGICVQDPTSPPIC--VNGEQRFSLQSVMKLVVAAAVMRAVD +ERRVALSDRVTVRREDLSVIQPIADIVSERGTSLGDLLRRAVVESDSAATDMLISRLGGT +KAIQAFLGESGLHGIRIDRTERELQTAYLTDPRDTASPRGMVGFLHKLAAGQLLSASSTA +HLLEVMKKTVTFPDRLRAGVPSGWTIGHKTGTSRNGVTNDVGILTAPDGRHVAVAAFVAE +SRTGNEERAAMIAASARAITAAy +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B6BE267 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKR------------ +------------------------------------------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD7EA47 +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMAGFLHGLATGQLLSASSTA +HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI0011AF77C7 +-----AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD +QGALNLEQIIHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT +ETVQKDLKEWGISGINVRFTEDEMLRNHELQYANSSRPSAMNALLRAFDEGKILNKDTQR +LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD +SKDSAPACEKVIASMARWLCTEw +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SKR6_9BACT +-----AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD +QGALNLEQIIHMRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT +ETVQKGLKEWGISGINVRFTEDEMLRNHELQYANSSRPSAMNALLRAFDEGKILNKDTQR +LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD +SKDSAPACEKVIASMARWLCTEw +>[subseq from] Class A beta-lactamase n=3 Tax=Cryobacterium TaxID=69578 RepID=A0A5F0EA32_9MICO +-----RSVRQLESTSGVMIAVSAKNVRSGRQI-NHRATEPVPMCSLFKVLAVANLLRLRG +YEDQYWNTPISFTAADLVVNSPVATASTSMSMTPNQMADAALRFSDNTAGNLLLRELGGP +ATITEFAQALGAKRTRLERIEPELNEGLPGDVRDTTTAEDMVAIMKALLIDGDAGQLARS +RLQDLMLRNTTSGKRARAGLSEPFELADKTGAGDYGIVNDAGVLWQGQRQTIAMCILTRT +EIASAPNSNDVIADATRLIVS-- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Flavobacteriaceae bacterium TaxID=1871037 RepID=A0A3B9DZ08_9FLAO +-eSLRTEINQILSSKNLTAGISLKNIENKDTL-SINGNQMMPMMSVFKFHIALAVLHEVD +QNKLKLNQRFFIKKEDLLPWSPILEDYPEGNLTLDQLLRYTVSHSDNNGCDILLKIIGGT +KTVQNFINKQGIKDFVIKVNEQEMQT-WDNLYLNTTSANATTKLLEKFYATKVLKKKSTT +YLYQLMVETSRGLTWMKAGLPENTELAHRTGISDTNAMNDIGIIKPINHQPIILSIYLKN +ITEERTETEKVITDITKAVWNYy +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium barchaimii TaxID=1420591 RepID=A0A147EET6_9SPHN +---LEQQLASLAEASRGRIGVAALDLTSGRTV-DVLGDQRFPMASTSKIAIAATFLEGVD +QGRFSLSSEFPMMMPVPSRSTAVAPVRPGTYMSARSLIEAMITRSNNYATDALLKVVGGP +RAVNDWVRRAGVNDWHIDRDIATLVRATTIDTRDSATPLAMVRLLSQIYSGQMLSPASRD +VLLGAMGRCLTGKRRIPALLPSGTTVLHKTGSLNN-TSSDVGIIQTPDGRAYAIAIYVTG +QG-TRLARETRIASIASALYHGy +>[subseq from] Beta-lactamase n=1 Tax=Alistipes sp. AF17-16 TaxID=2292190 RepID=A0A396M2D6_9BACT +---LVRQIDSVLSRYRATVGVTVLS-NRDEIV-AANDSILFPLMSVFKFHIALAVLDRMD +RNRTRLDSVVRIKASDMHPYSPLRERHPGRDITIAELLRYSVAHSDNNACDILLEYAGGP +EAVEKYVRGLGIENTFISASEKTMHDRIENQYLNRSTPTATARLIETFFENRLFASKYKK +FLIRIMTETSTGQDKLKGLLPPDCTVGHKTGSSDRTADNDAGFVLTPDGKRYYIAVFVSD +SQEDDPTNASIIARISAIVYD-- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium haifense TaxID=421525 RepID=A0A3N0WWI5_9FLAO +-tELRQELENIIATKNATIGISIKNIETKDTL-NINGTLNTPLMSIFKFHIALATLNLVD +KGKLSLKQKIFIKKEELHEWSPIRDEYLNGNLTLDQLLRYTVSHSDNNGCDILLKLIGGT +ETVQKFINKQGIKDFTIKVNEREMQT-WESLYINTTTPLATTEILEKFYKGQVLKKKTTK +YLYQIMVDCSRGITWMKAGLPEGTELAHRTGISDRASMNDVGIFKLPNGNHIILSVYLKN +ITEEREVTEKIIADIAKATWNYy +>[subseq from] Beta-lactamase n=1 Tax=Oxalobacter formigenes OXCC13 TaxID=556269 RepID=C3X8Y4_OXAFO +-qTLQEQVNAIVASHHAKIGIVIENADGSEQA-HYHSGDFFPMQSVFKFPIALAVLDKVD +KGELRFNQRIFLKKSDLRPWSPLREKYKNGNVSLKEILRTTMKDSDNNGCDILLKLAGGP +GAVTAYLREKGIKDMTVATTERTMHGDWNIQAKNRATPEATNRLLKLFYEKKLLKPDTQA +FLWAAMRDSMVSPERLRNGLPPKTPLIHKTGTSMGNTVNDIGIVVLPDGKPLFISVLVSH +GKEPKAKTEKMIARLSKTAWEHf +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas guangdongensis TaxID=1141890 RepID=A0A285QYN7_9SPHN +---LQSRVAAVATSDRGEIGVSALDLTTGARL-AVKGDTRFPMASAVKVAIAATYLAGVD +EGRWQLSTMYPLDEAMRVRSDGITDTLPHAGLSGANLIELSLTVSDNTATDMLLKVVGGP +AAVTKWLQGQGISGQRVDRTIARLLIAFDADPRDSSTPDAMVALLARLHDGKALKPASTR +FLFDVLARTKTGAKRVKALLPAGTRWAHKTGTLP-GISNDVGVLTLPNGHKVAVAVLSHG +IA-DPVARDAKLAEIGRILFDGf +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacter henricii TaxID=69395 RepID=UPI00068A3476 +--ALRKSFQALADKAPGLLGVAVRDAQTGQTV-AFNGDNRFPLQSVFKAALGAAVLAEID +AGKLRLDETITIRDIDLSPFSPVADAWPARTYTVAELLDRASGASDNTAADVLMKKIGGP +GALTAWLVLKNIKDFQIDRYERQLQPAYLADTRDTATPIAAITFLEALRAGQLLSRASTE +RLLAIMTATTTGKDQLKAAMSSSTTLAHKTGWARTDATNDIGVYTLKDGRQYAVAAFLSG +STASDAERDAIIADVGRIVLK-- +>[subseq from] Beta-lactamase class A n=2 Tax=Nitrospirillum amazonense TaxID=28077 RepID=A0A560G572_9PROT +--ALQARLDRLAQDFPGRGGIAVRDPATGTVA-EVKARERFPEQSVFKLTVAIALLDLVD +HGRMDLAQKVTLYPRDRSVWQPLAKNITPAGTTLDDLMARMVADSDNVAADTVLRLIGGP +AVVQAALTARGLDGIRVDRDERHLQSAYLSDPRDTAQPATMALLLERLDKGELLSPASTR +RLLDILDHTTTQPNRLKAGLVAGWTVAHKPGAGPTLANNDVGLMTAPDGHRYAVAVYVAS +VQGPRERADAFIASVARAVVESw +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=A0A5Q3LRK9_RHIML +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIVDIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATRQLLSASSTA +HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Class A beta-lactamase-related serine hydrolase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=A0A437G4D1_RHIML +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIVDIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATRQLLSASSTA +HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aureispira sp. CCB-QB1 TaxID=1313421 RepID=UPI000696B0D6 +-eTLREKITTVIENKSATVGVAIQGSNSNDSM-SINGHQHLPMQSVFKYHLALAVLHQVD +QGKLRLNKKIVIRKKDIQAWSPLRKKYPNGAVSIAELLQYTVALSDNLGCDILFKLIGGT +SVVQSFLHKIGIKDIAIHHNEMVMQSEWEKQYDNWTTAKAANQVLELFFENNLLSAQSHR +FLLETLKGTKTGKKSIRGLLPQATIVAHKTGHSGTGALNDIGIVFLSDNSYFYISILVSD +SMEEDSVNQQIIAEIAKLTWDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. OV715 TaxID=1500287 RepID=UPI00068B3A82 +--DLRQELKQIISTKNATVGISIKSIEDKDTL-SINGHLNAPMMSVFKFHIALATLNLVD +KGKISLAQKVFIKKEDLQQWSPIKDEYPNGNITIDQLLRYTVSHSDNNGCDILLKLIGGP +ETVQKFINRQGIKDFVIKVNEEEMR-IWKNLYINTTTPLATTDLLEKFYKGKVLKKATTQ +YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISSTNAMNDVGIVKLPNGKHFIISIYLKN +ITEKREDTEKIIADLTKATWN-- +>[subseq from] Serine hydrolase n=1 Tax=Nitrospirillum amazonense CBAmc TaxID=1441467 RepID=A0A248JQ79_9PROT +--ALQARLDRLAHDFPGQAGIAVRDGVTGAEM-GVKARERFPEQSVFKLTVAIALLDLVD +HGRMDLAQKVTLYPKDRSVWQPLAKNITPAGTTLDDLMARMVADSDNVAADTVLRLIGGP +AAVQAALTARGLDGIRVDRDERHLQSAYLSDPRDTAQPATMALLLDRLDKGELLSPASTR +RLLDILDHTTTQPNRLKAGLAAGWTVAHKPGAGPTLANNDVGLMTAPDGHRYAVAVYVAS +VQGPRERADAFIASVARAVVESw +>[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium sp. (strain PM2-P1-29) TaxID=403776 RepID=A0A077XS50_SPHSM +---LQQYINQIITGKNALVSVAISGISQNDTV-GVQASQRLPMQSVFKFPLAIVMLTEID +KGNFTLDQKIEITKRDLTPWSPIRDKYPDGVLTLREILEYTITLSDNIGCDVMLKLLGGP +QKVEQYFAKQGFKNISIKINEKTMQSNWDKQFLNWCTPQEMNNILKIFYVNNLLSMSMYD +FLWSTMKSTNTGLNQIKGQLPAGTVVAHKTGSSGTAALNDVGIVSLPNGEYFVISIFVTN +SKESKETNERMISDIAKVTWDYf +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2L1J137_ECOLX +------------------------------------------------------------ +-----------------------------GTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAAR------ +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. 36-9 TaxID=1895905 RepID=A0A1Q3ZAF4_9FLAO +-nDLRKELNQIISTKNATVGISIKGIEDKDTL-SINGNMAMPMMSVFKFHIALTVLNEVD +KGKFKLNQKFFIKKEDLHPWSPIREDFPNGNLTLDQILRNTVSHSDNNGCDFLLKILGGT +DTVQRFINKQGIKDFTIKVNEQQMS-VWENLYLNTTTPLATTLLLEKFYNGKVLKKETTK +YLYQIMVETSRGITWMKAGLPKGTELAHRTGISDRAAMNDVGIVKLPNGKHFILSVYLEN +ITEEREATEKIIADIAKVTWSYy +>[subseq from] CTX-M-90 extended-spectrum beta-lactamase (Fragment) n=1 Tax=mine drainage metagenome TaxID=410659 RepID=T1C031_9ZZZZ +--ALHAQFARIESQTGGRLGVAMLDTHNRIAA-GYRANQRFPVCSTWKLLAVAALLRQVD +EGHENLDRRIRFRASELVVYSPVTKDRVDATMSLRELCAAALVWSDNSAGNLLLAALGGP +SAITRFARAIGDPVTRLDRTEPALNEATPGDARDTTSPRAMLGDLDTLLLGNALTPPSRA +RLNAWLAASQTGAR---------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter zhengii TaxID=2307003 RepID=A0A418NTD7_9SPHN +---LERRIAQVADGSDGRIGVAAIDLATGEQV-SVLGDQRFPMASTSKIAIAATFLEGVD +QGRWSLTSEFPLLWAVRSQSTRVAPVREGEYMAAHQLIDLMITRSSNPATDALLAAVGGP +AAVNDWARRAGLNDFSLDRDIATLVRTYHIDLRDSATPETMARLLAGIYQGEWLSAESRD +VILDAMERCRTGRNRIRGMMPEGVSVAHKTGTLNR-MAGDIGIIEMPDGRAIALAIYVTG +QSASRRLRDSRIASIARALYDG- +>[subseq from] class A beta-lactamase n=1 Tax=Chitinophaga vietnamensis TaxID=2593957 RepID=UPI001178A659 +-qSLQARLQEVAATIKGKTGVYAEVLETGDTA-SLHATTHYPMQSVYKFPIALAILQEVD +KGRLRLDQPVQIRKSVLTLHSPIRDSFPEGTMPLREVLRYNTCESDGTACDVLLGLLGGT +RNAEKAIHALGVRDIAIATTEKVQMEDELVQYRNWCTPAAMAQLLRIFYTKNILSPASKA +LLIKDMTETPVGLKRLKGELPPGTTVVHKTGTSNTRATNDVGIITLPNGKHLAIAVFVSD +AYGSTAEREGIIAQMARLCFDAf +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A6D1LUI7_ECOLX +-----------------------------------------------------------E +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTQPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIW--------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Luteibacter yeojuensis TaxID=345309 RepID=UPI001419FFA5 +--RLQQTLARLADEAPGTLGITVLDLGAHTRT-RINADRAYPMMSVFKAPVAAAILAQID +EGRLRPDQEVTIDSGDVLGGSPSIGAHFKGKFTVDRLLEAAVSESDNTAVDALIRLAGGP +QVVTAYLRKHGIDGMRIDLGEAGIVDAYMADPRNRTTPDAAADFLEKLWKGELLSATSTK +RLLALMYGQTV-PNRMRAGLPAGVRFADKCGTSYTAAFNDIGIVTWPDGRTVIVAAFLTG +SQTDAKDRNALFAEIGRAVT--- +>[subseq from] Uncharacterized protein n=1 Tax=Bosea vaviloviae TaxID=1526658 RepID=A0A0N0MCD3_9BRAD +-aKLDKEIAAIERQSQGRLGVALLDLRDRKTW-SHRGTESFPMQSVFKWPLAIAALQAVE +AGKLQLDQPITIRRSEFSLHSPLAKAFKGDSYPLRELIALAAGESDNTAADILMREIGGP +KVVSAMLRDGGISGISVDRYERQFQPAALKDKRDSATPEASVLFVEAQAKGNWLRDPAHN +ALIDIVTQTKSGPDRIRAGLPQGAGFAHKTGAGLNHATNDIGLVTLPNGRVFAIAVYLVG +STADAKEREAAHAAVAKAAVS-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. GA093 TaxID=2683249 RepID=UPI001365C1E3 +---LRNKIEQILSKKNAVVGVSIIGNNGKDTL-SLNGERRFPMQSVFKFHIALAVLSEID +KGKLSIDQKIEIGKDELLPWSPLRDENPNGGFTIERLIQYSVSHSDNTACDVLIRLIGTP +KTVEEYIKKSGVNDIQITFNEEEMQKKLENMFQNWTTPKAASQTLKLFYENKLLSKNSYD +FFWKTNIETTTALSRIRGLLPKEIIVAHKSGSSGTNAVNNIGIVFLPDGEYFYISVFVTK +SHENAKTNDRIIADIAKATYDFy +>[subseq from] Uncharacterized protein n=1 Tax=Luteimonas sp. FCS-9 TaxID=1547516 RepID=A0A0H1ALI5_9GAMM +-----GDIGSLEAASGGRLGLCLLGPDRRRVV-AHRARESFPTASTIKFALSAAVLAQAD +AGALSLDDRIAVRAQDIRSGASVTGRHVGKDMTVRDLCRGSMVWSDNPAVGLLLPLVGGA +PGLQAFLRRHGDADTRTDGIAEGA---------STTSPDTMARNLARFVLDDALSRPSRL +QLADWLIENRTGDARIRAGMPAGWRVGDKTGGMA-GVSNDIAVLWPPGGVPWLLALYLQG +SPLQAGARDAVLRRATELVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Demequina aurantiaca TaxID=676200 RepID=UPI0007810840 +-------------EYDAEVSVSVVEPGGAEPF-GFHHTERRGFASTIKAVIAAAAFAQLS +--ADERDETVTWTREKVSLYSPVTSEHFDDGLTLSELIEASVRYSDNTATNLVLQRIGGP +DVVNEALAALGDDVTNLADEEPALNYISEASAANTTTSLAIAQTLQNIVDSDYLEAEDRT +LLLDLMSGNATGDSLIRAGAPAGWEIADKSGGAG-AIRNDIAVAYPPQGDPVIITILTTR +TDRSKPYDDKLVEDAASAVFD-- +>[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI0012E15568 +-----AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD +QGALNLEQIIHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT +ETVQKDLKEWGISGINVRFTEDEMLRNHDLQYANSSRPSAMNALLRAFDEGKILNKDTQR +LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD +SKDSAPACEKVIASMARWLCTEw +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Empedobacter brevis TaxID=247 RepID=A0A5P2G8U4_9FLAO +-eRLRTEINQIISSKNLTAGISLKNIENKDTL-SINGNQMMPMMSVFKFHIALTVLHEVD +QNKLQLDQKFFIKKKDLLPWSPILDDFPEGNLTLDQLLRYTVSHSDNNGCDILLKIIGGT +KIVQNFIHKQGVKDFVIKVNEQEMQK-WDNLYINTTSANATAKLLEKFYTNKVLKKNSTT +YLYQLMVETSRGSTWMKAGLPANTELAHRTGISDTNAMNDIGIIKLVDGKRIILSIYLKN +ITEERAETEKVMADITKAVWNYy +>[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI0011AF8AD3 +-----AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD +QGALNLEQIIHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT +ETVQKDLKEWGISGINVRFTEDEMLRNHDLQYANSSRPSAMNALLRAFDEGKILNKDTQR +LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD +SKDSAPACEKVIASMARWLCTEw +>[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI0011AED421 +-----AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD +QGALNLEQIIHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT +ETVQKDLKEWGLSGINVRFTEDEMLRNHDLQYANSSRPSAMNALLRAFDEGKILNKDTQR +LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD +SKDSAPACEKVIASMARWLCTEw +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A127SSQ5_9BACT +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYTGGI +GHIHQYIRKLGINDFNLSETEDSMHRNPQKAYANWSTPSEMVRLLKMADEKDLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGIVIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=A0A414PZW1_BACSE +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFNLSETEDSMHRNPQKAYANWSTPSEMVRLLKMADEKDLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina pacifica TaxID=1296415 RepID=UPI00046ECEDA +---LRNEIEKIISDKNAVVGVSIIGNNGKDTL-SVNGDKQFPMQSVFKFHIALAVLSEID +KGALSLDQIVKIDKDELWKWSPLRDENPNGGFTIEKLIQYTISQSDNTACDVLIRLIGTP +KTVEGYMKKSGIEDIQITFDEKEMQEKWENMFQNWTTPNAANKTLKIFFENNLLSKRSYD +FFWKTNIETTTALGRIRGQLPKEVVVAHKSGSSGTNAVNNIGIVFLPDGEYFYISVFVTN +SHENNKMNDKIIADIAKATYDFy +>[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia TaxID=28110 RepID=A0A0E2ZXD4_9GAMM +--TLDDSFKNLEDKYHGKLGIYTLNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM +QDKGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL +EKLNKLVAKLGDKDTIIKNDEPKINHTKPDSNINKTTPKAITQDIYNLAFGNILDKKHRE +IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQNKPPFALSILYTN +PSVKAPSNEKIIQQASKLTAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium sp. Gsoil 351 TaxID=2675225 RepID=UPI0012B4AFA2 +-rALETQLRAIVANSGGRIGIYAADVDGPRAV-TINANQAFPMASTVKVAIAAAYLQGVD +DGRLRLDTAYPLRIGTGQTGADGRVTREGMSLSAQSLIELMITKSDNQATDAILSAVGGP +AEVNRWLLGAGISGLRVDRDIATLLRVLGLDKRDTVTPAAMVRLLGALHRGEVLSPQSRA +VLLGAMSRCKTGKTRIPALLPEGTLIAHKTGTLW-AQTSDVGIIRLPDGRNVALAVYVTG +QS-SHAAQAQTIAQVARTVYDSf +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. PhB165 TaxID=2485105 RepID=A0A4R1UPS3_9SPHN +--DFERRLASVAEGSQGRIGVAAVDLSTGRSV-DVLGSQRFPMASTAKVAIAATFLEGVD +KGKWSLSSEYPLMIPVASASSSVAPVRPGAYMSARQLLELMITRSNNYATDALLKVVGGP +SAVNAWVRRAGIDDWHLDHDIATMVRAKVVDKRDSATPLAMVQLLTGIYQGKWLTPESRD +VLMGAMGRCLTGRNRIRAGLPSGVNVSHKTGSLSN-TSSDVGIIETADGRAYAVAIYVTG +QG-NRPAREARIASITRTIYEGy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=UPI000E4BACE4 +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REKIPLKHIVHVKASQLQPYSPMRQKHSSQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFNLSETEDSMHRNPQKAYSNWSTPSEMVRLLKMADEKDLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium 2SD TaxID=2502200 RepID=UPI0010F60500 +--KLDAGIKTIEQSTKGRIGVGLIDLKDRKSW-SYRGTEPFPLQSVFKLPLAIGVLQAVE +AGKFKLDQPITVTRNDLSLHSPLAKAFKGERYPLRELLTLSTGQSDNTAADLLLRLIGGP +QALTALLKDGGVTGISVDRYERVFQPATLADKRDAASPEASIAFLEGLAKGNWLREPANA +ALLDIMLEAKTGPNRIKAGLPKGARFAHKTGLGPNHATNDIGIVTLPDGRRFAIAVYLAG +AKVGEKEREAAHAAVAKLAVE-- +>[subseq from] Beta-lactamase n=2 Tax=Dyella japonica TaxID=231455 RepID=A0A0G9H3W8_9GAMM +---LQHALDALAQRAPGTLGVAVLDLKSGAAA-GVDADRAFPMMSVFKAPVAAAVLSRID +DGSLSLQQSVTVTRDQVMGGSPSLGAHFHGEFTVEQLLKAAVTESDNTAVNALIRVAGGP +GVVTTYLHAHGIDGMRVDVDEAGIAQAFLADPRNRSTPDAAIAFLRKLVQGELLSPVSTQ +RLLALMEAQTI-PNRLRAGLPAGLRFADKTGTSGTAAFNDIGIIRWPDGHTVLVAAFLMD +SPASDPQRAALFADMARTVA--- +>[subseq from] Uncharacterized protein n=1 Tax=Spirosoma radiotolerans TaxID=1379870 RepID=A0A0E3ZWL8_9BACT +---LSQELMRLSDMSGGKVGICATHIETGKTI-TQNGKEGFPMASSYKVAIATQLLTRVD +SGSLTLAQLVPITKSDFHPGSGMLS-----SLSVRSLLELMLLISDNSATDICLRLAGGP +AAVNACMKRIGVEGLRVDRPTAWLIAAFENDPRDTSTPEAMTLLLTKLYTQPVLKPASQA +LVLDIMKRCETGLARLKGALPPDTEVLHKTGTIGL-TASDVGIITLPGNGHVAISVFVKA +SHKDGPVRERTIAEVTRTIYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD71192 +--RLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIVDIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATRQLLSASSTA +HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Beta-lactamase class A n=1 Tax=Altererythrobacter ishigakiensis TaxID=476157 RepID=A0A562UU68_9SPHN +--RLAAKLNIIEAASGGTLGVAFLNTATGAIM-GHNLGTRFGHCSSFKLSLAALTLWRDQ +QSIDDADRLVRWSEDELVAYSPFTAPRTEQGATLSALAEATQKTSDNSAANVLLREFGGP +EALTRFWRLIGDTGSRLDRIEPALNHVPKGELRDTTTPAAMVRTVAALCFGEVLKDANRQ +TLRQWVVDTKTGARRVRAGLPEGWTAGDKTGTSFASLYVDIGFATPPARAPLTFATYYRA +PNIQDPRSEQVLAQVGEVLAE-- +>[subseq from] Beta-lactamase n=1 Tax=Spirochaetes bacterium ADurb.Bin215 TaxID=1852910 RepID=A0A1V5WJB8_9SPIR +-dALREQIESITAKSNARTGVALYDPVKRDTV-ALNGTSQFPMHSVMKFPVALAVLSEID +KGNLSLKQRVTITSEDLEPWSPIKAAYPDGTLTIEQILKYTVADSDNIGCDILLRLIGGT +MSVQKFLDTHGFTGISIGATEQEMHDDPDKQYLNSSSPGAMNKLLSAAYTGALLSRESHE +WIWKTLQEATTGGTRIKGLLPKTAIVAHKTGTSGIAAVNDVGVLILPDGNVLYLSVFVAD +SRETPAETEKIIAEIAKAVWDHy +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides intestinalis TaxID=329854 RepID=A0A3E4KXU1_9BACE +-kELEQQIGQVLKDKKATVGVAVLANDTIVA--LHNNQIHFPLFSVFKFHVALAVLDKMD +KGHVSLDSIMKIKAAQMLPYSPLRQKFPDRDISLGELLKYSISLSDNNACDVLIDYVGGI +DKVNSYIKSLGLKDFNLAANEELMHRDVATQYQNWSTPEAVVRLLNIADKQTLFAAEYKD +FLWQILKETSTGTDKLKGQLPPDVIVGHKTGSSDKTADNDAGFIILPDGRKYYITVLVME +SQETDQENAAIIARISKIVYD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD967A1 +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRCIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI00130E7BB2 +-aKLDKEIAVIERQSRGRLGVALLDLRDRKTW-SHRGAESFPMQSVFKWPLAIAALQAVE +AGKLKLDQPITIKRSEFSLNSPLAKAFKGESYPLRELIALAAGESDNTAADILMREIGGP +KAVTAMLKGGGISGISVDRYERQFQPAALKDKRDSATPEASVLFVEAQAKGNWLRDPAHS +ALIKIVTETKSGPDRIRAGLPEGARLAHKTGAGLNHATNDIGLVTLPNGRVFAIAVYLAG +SSADAKQREATHAAVAKAAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium oleae TaxID=491207 RepID=A0A1I4VXY8_9FLAO +--DLRKELKQIISTKNATVGISIKSIEDKDTL-NINGHLNAPMMSVFKFHIALATLNLVD +KGKISLAQKVFIKKEDLQQWSPIKDEYPNGNLTIDQLLRYTVSHSDNNGCDILLKLIGGP +ETVQKFINRQGIKDFVIKVNEEEMR-IWKNLYINTTTPLATTDLLEKFYKGKVLKKATTQ +YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISSRAAMNDVGIVKLPNGKHFIISIYLKN +ITEKREDTEKIIADLTKATWN-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000488BF2E +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHGLATGQLLSASSTA +HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Alistipes sp. AF48-12 TaxID=2291998 RepID=UPI000E511D91 +--TLVRQIDSVLSRYRATVGVAVLS-DRDEIV-AANDSILFPLMSVFKFHTALAVLDRMD +KNRTPLDSVVRIKASDMHPYSPLRERHPGRDITIAELLRYSVAHSDNNACDILLEYAGGP +EAVEKYVRGLGIENTFISASEKTMHDRIENQYLNRSTPTATARLIETFFENRLFASKYKK +FLIRIMTETSTGQDKLKSLLPPDCTVGHKTGSSDRTADNDAGFVLTPDGKRYYIAVFVSD +SQEDDPTNASIIARISAIVYD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD98AB5 +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHGLATGQLLSASSTA +HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Beta-lactamase n=1 Tax=Dyella sp. AD56 TaxID=1528744 RepID=A0A2N7QPC5_9GAMM +-eTLQHSLEALAQRAPGVLGIAVLDLNSGASA-RVNADQAFPMMSVFKAPVAAAVLSHVD +SGTLSLQQPVTITRDQVMGGSAIPANFRGERFTVEQLLKAAVSESDNTAVNALIRTLGGP +SVVTDYLRAHGIDGMRIDIDEAIVSQAFLADPRNRSTPDAAIVFLHKLVGRELLSPASTQ +RLLALMEAQTI-PNRLRAGLPQGVRLADKTGSSGRAAYNDIGIVTWPDGHRVLVAAFLLD +SPGSDKARDALYADIARSVV--- +>[subseq from] Beta-lactamase n=2 Tax=Novosphingobium sp. 9U TaxID=2653158 RepID=A0A653J5T8_9SPHN +---FEQQLAALAEGSQGRIGVAALDLGTGRTV-DVLGDQRFPMASTSKIAIAATFLEGVD +QGRFSLSSEYPMMMPLPSKSSSVAPVRPGTYMSARSLIEAMITRSNNYATDALLKVVGGP +RAVNDWVRRAGVTDWHIDRDIATLVRATTIDSRDSATPLAMVRLLSQIYNGQMLSGSSRD +VLLGAMGRCVTGKRRIPALLPMGTTVLHKTGSLAN-TSSDVGIIRAPDGRAYAVAIYVTG +QG-NRLNRESRIASIARALFHGy +>[subseq from] Beta-lactamase class A n=1 Tax=Porphyrobacter sanguineus TaxID=198312 RepID=A0A1M7SSC2_9SPHN +--RLAAQLRLIEAQGNGTLGVELFDTATGLSV-GINRDRRFGHASSFKLSLAALLLERDA +AGAIDGDKRVMWDEADMLQHAPFTRDRMAKGATLRELARATQVTSDNPAANILLRELGGP +AALTAFWRSIGDEISRVDRTEPEMNNVPTSEFRDTTTPAAMARTVAKIIYGDVLPEAARA +ELKGWMIATETGLRRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKGPPITFACYFRA +RQSELASGEMTLARVGA------ +>[subseq from] Beta-lactamase n=1 Tax=Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8) TaxID=682795 RepID=G8P1Y7_GRAMM +---LHQQLATIAKDAHGQVFVACSLPGVALDC-NLNPHGHPPMQSTFKLPLAVALLQQVE +RGKLKLDQPIRFLPSDRYPYSPLQDAHPEANVPLHDLLQLSVGESDNTATDILLRLIGGP +QAVQESMNKLALPAIHVRDSERGLHDDFQAQYRNDAEPAAMVTLLRMLADHSPLSAEHTA +LLNRWMTESSTGPHRIKGLLPAGTPVAHKTGTSGEHATNDVGLITLPNGQRLALAIFVTD +AHADETTRDAVIARIAKAIYD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000EFB45BC +-dRLRSELTVLANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Beta-lactamase class A n=2 Tax=Nitrospirillum amazonense TaxID=28077 RepID=A0A560F4Z7_9PROT +--ALQARLQRLTHDFPGRAGIAVRDGVTGAEV-GVKARERFPEQSVFKLTVAIALLDLVD +HGRMDLAQKVTLYPQDRSVWQPLAKNITPAGTTLGDLMARMVADSDNVAADTVLRLVGGP +AVVQAALTARGLDGIRVDRDERHLQSAYLSDPRDTAQPATMALLLDRLDKGELLSPASTR +RLLDILDHTTTQPNRLKAGLAAGWAVAHKPGAGPTLANNDVGLMTAPDGHRYAVAVYVAS +VQGPRERADAFIAGVARAVVESw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI0012970065 +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAGFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Beta-lactamase n=2 Tax=Novosphingobium sp. B1 TaxID=1938756 RepID=A0A1W2BKZ2_9SPHN +-qAIQQQVAAIAAEGRGRIGVAAMDLDGGGQI-FVNGDMPFPMASTAKIAVAATFLEQVE +KGAYRLDQQFPMMVRVAERGAPSPEARAGTVMTAQSLMELMITRSHNEATDGLITAVGGV +QNVNRWLTRNGITGQRLDHTMATLVRARVIDTRTSSTPRAMVALLAAIDRGNVMSPESRA +VLLDTMTRTSTGKTRIRAGLPEGTLVAHKTGTLS-GVTDDVGIVRLPDGRHLALVFFVTG +PEG-HAAHAGLIARMTRAIYDGy +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. ABRDHK2 TaxID=2571749 RepID=A0A4D7DC53_9SPHN +---IQQQIAAIASQSRGRIGVAAMDLDGGGQI-FLNGDMPFPMASTAKIAVAATFLEGVE +QGRFRLDQRFPMMLSVPERRSPIAPVRAGPVMTAQELMELMITRSNNQATDGLIAAIGGI +SPVNQWLTRKGIVGQRLDHTMATLVRATVIDTRTSSTPRAMLALLAAIDRGGALNPESRA +VLLDTMTRTSTGRNRIRAGLPEGTLVAHKTGTLA-GVTDDVGIVRLPDGRHLAMVVFVAG +PEG-HAVQSTLIAQVARVLYDGy +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=C7F8X1_ECOLX +------------------------------------------CGSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTG----------------------------- +----------------------- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides salyersiae TaxID=291644 RepID=UPI0003270634 +---LKADFDKLLQDKQATVGVAVVS-DGRKTF-TYNNQHHFPLMSVFKFHQALAVLNYLD +RKQLPLTTEILIRKADLLPYSPLREARPEGGMSVGELLRYSVSESDNNACDILFRYIGGV +EVVDKYIRTLGITDFKIEATEEDMHEGFRYQYLNWTTPLAAVRALEKFCTETLFRHSYKE +FLEKIMMETVTGKDKLKAGLPPAVVLGHKTGSSDKAGDNDMGFVRLPDGSRYSIAVFVKD +SKEDDKTNAALIAAISQKVYEYy +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces albus TaxID=1888 RepID=A0A0B5EVB2_STRA4 +------------------------------------------------------------ +--ARALAELVRYSRADLLPDSPVTGEHLGQGLSLAALCEAAVRHGDRTAGNLLLRHLGGP +GALTRFARSVGDRVTRLDRWEPELNSAEPDRRTDTTTPYAIARTYAHLTVGDALGTADSC +LLTGWMRQHTAGPARFRTGLPAGWLLADTTGGGPYGTGHDVGIAWTPEGTPLLLACLTRG +SEPGEEPDEALLAETAALLA--- +>[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. FSY-8 TaxID=1908523 RepID=UPI0013767E0C +-----LQLARLANASMGRIGVAAVDLSTGKGV-SVMGDQPFPMASTSKIAIVATFLEGVD +QGRFRLTDRFPLMMPVPSASSVVAPVRPGSSLTAHELIELAITRSDNHATDALLAAVGGP +QAVTGWMKRAGLHGMRLDRDIATLVRARVIDPRDSATPQAMATLLAGIYQGQWLSNSSRD +VLLGAMSRCVTGRSRLRAQLPADAMVGHKTGTLNN-TSSDVGLIRASDGRMIAVAIYVTG +QG-GKPGRDSRIATIARAIYEGy +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter confluentis TaxID=1849021 RepID=UPI00136CE9B3 +---LEQRIARLAVGDKGRIGVAAVDLTTGAEL-SVLGDQRFPMASTSKIAIAATFLEGVE +QGRWSLSSEFPLLVPVRSAYSTRVAPVSKGQLAASELIELMITRSSNSATDALLAAVGGP +KAVNDWTRRAGIREFRLDRDIATLVRAAHIDLRDSASPKAMIDLLSGLYQGKFLNSSSRR +VILGAMERCRTGKRRIPALLPASAQVAHKTGSLNN-TSSDIGIIQTPDGRAIAVAIYVTG +QG-SRLAREDRIAQIARAVYDGy +>[subseq from] Beta-lactamase n=1 Tax=Aequorivita lipolytica TaxID=153267 RepID=A0A5C6YNZ0_9FLAO +---LRNQIEQIIAAKNAAVGVSLFGLETGDTL-SINGNKNYPMLSVFKFHIALTVLNKVD +KGELSLNQKLFIKKSELLEWSPFRDKFPDGNITLKEAIQWTVKNSDNNICDILIRLIGGV +KTIDSFINN---PDFIIVNNEEDMHQNWEAQFLNTTTPNNATHLLKKLFQTQILTKSSTK +FLYKTMLETSVGQNRIKGKLPKNTEVAHRTGSSFTGAINDIGIVKLPNGQHFAISVFVHN +TTEKFKDGEEIIADIAKATWDYy +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2W6W8U9_9SPHN +--RLEAEFARFAAMTDGTVGIAVRRLNDAPML-VLNGNTLFPMASTYKVAVAGTILSQVD +RGALTLDTMLPVDHRMLVSGIADTMPHPGLAMSVYNLMDLMLTRSDNSATDVLVNQAGGP +AAITAWLRSVGVRDQRVDDNTAQLLYAFAEDPRDTSTPEAMIDLLAKIAQGKALKPGTTQ +VMLEIMARCHTGEHRLKAMLPPGTPIAHKTGSLN-GLGNDVGIISLPDGTSFAIAVFVMK +DTKGKDARDRVMAEAARAAHDYf +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Acinetobacter baumannii TaxID=470 RepID=Q19RM1_ACIBA +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIMRRCS------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A2W6WGN8_SPHSX +---LEAQFAFLAKQTDGIVGVAVQKVGSSEIM-TLNKGVTFPMASTFKVAVAARIFEKID +KGELTLDQIIPVDPKILVGGLAVMTPHDGISLSVHNLLELMITISDNTSTDVLVQLAGGP +AAVTDWLTRHGIKGQRIDADTAHLIYPFNADPRDTSTPEAMVQLLLLIESGKALSADSTK +ELLAIMGRCTTGEKRLKGLLPIGTVVAHKTGTLMS-VANDVGFITLPDGSRFAIAVFVKG +DTKGTETQDRVIAEMARTAYDYy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina macrocephali TaxID=666563 RepID=UPI001268253A +-eTLRQKIDSIINTKKAIVGVAINGIKVKDTL-SINGQRHFPMQSVFKFPIALTILSEID +KGNLSLNQKIDIKKSELLPWSPIRRKYPEGGLTIAEIIKYTVALSDNVGCDVLLKLLGEP +QVVENHFSSLGFKDFAVKINEETMQNNWDSQFLNWTIPKEANKILATFYENKLLSKKSYD +FIWNIMKGTKTGKNRLRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPNGEYFTISVFVTE +SVEDFETNEKIISDISKAAWDYf +>[subseq from] Class A beta-lactamase n=2 Tax=Flavobacteriaceae bacterium CRH TaxID=1742859 RepID=A0A101CQQ2_9FLAO +-----------IASKNATVGVSMKGIEEKDTL-SINGNLKAPMMSIFKFHIALTVLNQVD +RGILKLDQKIFIKKEDLHSWSPMREEFPDGNFTLDQLLRYTVSHSDNNGCDILLKFIGGP +KTVQKFINKQGIQDFVIKVNEQEMS-IWENLYLNTTTPEATTKLLEKFYKGEILKKSSTK +YLYQLMVETSRGKTWMKAGLPENTELAHRTGISGRAGMNDIGIVKLPNGKHFILAIFLKN +ITEEFEDTERIIADITKAVWEY- +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingobacterium sp. 40-24 TaxID=1895843 RepID=A0A1Q4G7Y9_9SPHI +-nSLRKELHQIIATKNATVCISMKGIGTKDTL-SINGHLNAPLMSVFKFHIALATLNLVD +QGKLSLSQKFFIKKEDLHAWSPIREEFPNGNLTLDQLLQYTVSHSDNNGCDILLDLIGGP +ETVQKFIHKQGIKDFTIKVNEQEMRT-WENLYVNTTTPLASTELLEKFYAGQVLKKNTTK +YLYQLMVECSRGLTWMKAGLPKGTELAHRTGISDRAAMNDVGIFKLPNGNHVVLSVYLKD +ITEEREVTEKIIADITKAIWNYy +>[subseq from] Beta-lactamase n=2 Tax=unclassified Novosphingobium TaxID=2644732 RepID=A0A1E4MAL2_9SPHN +---IQQQIAAIASQSRGRIGVAAMDLDGGGQI-FLNGDMPFPMASTAKIAVAATFLEGVE +QGRFRLDQRFPMMLSVAERRSPIAPVRAGPVMTAQELMELMITRSNNQATDGIIAAIGGI +APVNQWLTRKGIVGQRLDHTMATLVRATVIDTRTSSTPRAMLALLAAIDRGGALNPESRA +VLLDTMTRTSTGRNRIRAGLPEGTLVAHKTGTLA-GVTDDVGIVRLPDGRHLAMVVFVAG +PEG-HGPHSALIAQVARVLYDGy +>[subseq from] Beta-lactamase n=1 Tax=Algoriphagus lacus TaxID=2056311 RepID=A0A418PN94_9BACT +--ALRETIVEYLAEKNALVGVSIIGNDGKDTL-SINGERRFPMQSVFKFHIALAVLSEVD +KGNLSLDQEVLIKKEELLNWSPLRDENPEGGFTIKQLIQYTVSHSDNTACDLLIGLIGTP +KDVETYFKKNGIQDIEITFNEKEMQANWDNMFKNWTTPIAASETLALFYEDNLLSESSHE +FFWRTNVETSTGENRIKGKLPKGTIVAHKTGWSGTAAVNNIGIVFLPNGEYFIISVFVTE +SKESFEVNEMIIADIAKVTYDFy +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacteria TaxID=2 RepID=A0A2U9Q5E4_PSEAI +------------------------------EI-LDRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPA-------------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter marinus TaxID=538382 RepID=UPI001361AED4 +---FEQRIAIAADGSKGRIGVSVLDLATGQEF-SILGDQRFPMASTSKIAIAATFLEGVE +QGRWSLSSEFPLLFPLRSQSSPKAPVRRGKHLPASELIELMITRSSNPATDALLAVVGGP +EAVNDWMRRAGIEDFQLTRDIATLVRAAAIDLRDSATPRAMTKLLAGLYQGRWLSPSSRA +VIIGAMERCRTGKRRIPALLPAGATVAHKTGSLNN-TSSDIGIINTPDGRAFAVAIYVTG +QG-SRLARESRIAQIARAAYAGy +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. A27 TaxID=1755991 RepID=UPI001177C70B +hdRLQATLEQYARSAPGLLGIAVLDMRSSAEW-HVNGERPFPMMSVFKAPLAAAVLDLVD +KGRLPLDRRVTITRDQLRAESAIRTNFQGERFAVAELLRAAVSESDNTAADALMRAIGGP +SVVTAYLHAHGIDGMHVEMDEGQVAEAYLDDPRNRSTPVAAVDFLRKLVSGALLSPASTQ +QLLTLMRDQTS-PRRLRAGLPADVTFADKCGTSLTAAFNDIGIMTWPDGRRVIVAAFLMA +SAASRADRDKLFADLAKAVAQ-- +>[subseq from] class A beta-lactamase n=1 Tax=Olivibacter sp. XZL3 TaxID=1735116 RepID=UPI0010658C5F +---LQTQFEQIAKNTKGNVGVCALIIETGESI-SFNGDKAFPMQSVYKFPIAMAVLKKVD +EGELSLDKMIEVDQSEYIPHSPIRDNFPKGTLTIRDLLKYNIEESDGTACDVLLRLLGGT +KNAERYIHKLGIMDIAISTTEMVQVANDTIQYQNWATPKAMSQLLKTFYAAGDLSKNSSA +LLLGYMSVSSYFDRRIKGLLPQETAVAHKTGTAGTRATNDVGIITLPNDQHLAVSVFISD +SYDSQKERELTIAKISRAAFDYw +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000716E3BE +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRN------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=A0A4Q5G8R5_BACSE +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REKIPLKHIVHVKASQLQPYSPMRQKHSSQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFTLSETEDSMHRNPQKAYSNWSTPSEMVRLLKMADEKDLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] FTU family class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI0000F5914B +--QLDDSFKNLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM +HNQGFLDKKIPINQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDSPASNILVRELGGL +QNLNKFIKKLGDNDTIITADEPEINYTQPHSNINKTTPKAITKDIYKLAFGNILDKKHKD +IFIKYLQDNNTGANRIAFGMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN +PNKNAPSNEEIIQQAAKLIAN-- +>[subseq from] Beta-lactamase n=1 Tax=Francisella tularensis subsp. mediasiatica TaxID=135248 RepID=A0A4Q7HGT1_FRATU +--QLDDSFKNLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM +HNQGFLDKKIPINQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDSPASNILVRELGGL +QNLNKFIKKLGDNDTIITADEPEINYTQPHSNINKTTPKAITKDIYKLAFGNILDKKHKD +IFIKYLQDNNTGANRIAFGMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN +PNKNAPSNEEIIQQAAKLIAN-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A649UHG5_ECOLX +------------------------------------------------------------ +----------HYRQQDLVDYSPVSEKHLADGMTTGELCAAAITMNDNCAAYMLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLSAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEH- +>[subseq from] HGA-1 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=C8C0M0_9ZZZZ +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNKVHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLQQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFNLSETEDSMHRNPQKAYANWSTPSEMVRLLKMADEKNLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGIVIMPGGKKYYIAVFVTD +SSETDEEDAAIIAHISRIVYDE- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium fuchskuhlense TaxID=1117702 RepID=A0A124JVF0_9SPHN +--AIEQQVAAIVAQGRGRVGVAAVDLDGGGQI-MINGDMPFPMASTAKIAIAATYLAGVE +QGRLRLDQQFPMMVPVAESRGTVAAVRPGEVMTAQSLMELSITRSDNHATDGLIAAVGGI +GAVNTWLSRIGVSGQHLDHTMATLVRVTTIDTRTSSTPRAMAQLLTAIDRGGALSPESRA +VLLDTMTRTSTGRNRIRSGLPEGVVFAHKTGTLA-GVTDDVGIVRLPDGRHLAIAIFVTG +PEG-HTAHASMIAQIARVLYDGy +>[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A2N8HHV4_9BACT +-----AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD +QGALNLEQIIHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT +ETVQKDLKEWGISGINVRFTEDEMLRNHDLQYANSSRPSAMNALLRAFDEGKILNKGTQR +LLWDMMTGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD +SKDSAPACEKVIASMARWLCTEw +>[subseq from] Beta-lactamase n=1 Tax=Flavobacterium kingsejongi TaxID=1678728 RepID=A0A2S1LS47_9FLAO +-tKLEEQIIVLSAPFKAKIGVTALVLETEEILvSFHGGDRFPMQSVYKFPIAMAILNEVD +QGRLQLHQKIKVEPSEIIPVSPIREKYPQGALTLSELLRLNIVDSDGTACDVLLRIMGGT +AKVQHYLNSLGITGINIATTEMVQVSDDWIQYQNWSTPDAMTQLLYLFYSKKVLSTPSRL +LLLKWMEESIPGAKRLKGALPKNAIVAHKPGTSGTNATNDVGIITLPNGNHLAISVFVAD +TYVSREEREGLIAAIAKMAWDY- +>[subseq from] Beta-lactamase n=2 Tax=[Pseudomonas] mesoacidophila TaxID=265293 RepID=A0A2A4FM08_9BURK +hdRLQATLDRFARAAPGTLGIAVFDMHGSAEW-HVNGDRSFPMMSVFKAPLAAAVLDRVE +RGQLALNQRVTITRDQLRPESDIRDTFQGDRFSVDALLHAAVSKSDNTAADALLKVVGGP +GVVTAFLRAHGIDGMRVDMGESQVSEAYLSDSRNRSTPVAAADFLRKLSTGALLSATSTQ +YLMTLLREQTN-PRRLRTGLPAGVTLADKCGTSPTAAFNDIGVMTWPDGRRMIVAVFLTA +SPASRADRDRLFADLAKAVAQ-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=G8FXI6_9BACT +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLRQKHSSQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFNLSETEDSMHRNPQKAYANWSTPSEMVRLLKMADEKDLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGIVIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q3V775_STEMA +----ATDFAALEKACSGRLGVTLLDTGSGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE +RDPALLDQRLPVRAQDILEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP +PAVTAFLRASGDTITRSDRLEPELNSFAIDDPRDTTTPAAIAATLQRLVLGDALKPASRQ +QLADWLIDNRN------------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium japonicum TaxID=375 RepID=UPI0005779106 +------ELESYERETGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARAD +RGEEQLAAVIPYGKADLLDYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP +AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVVGEALSPASRT +QLTEWMV----------------------------------------------------- +----------------------- +>[subseq from] Class A beta-lactamase n=2 Tax=Motilimonas sp. PLHSC7-2 TaxID=2303987 RepID=A0A418YBJ2_9GAMM +---VLPQVKTLQGQVQGQISLAVMASDGAWLW-HYQGQTSVALMSTFKPFACAKLLNDFE +QGRVSKEHKVMVEADTLQAYSPVAKDWLNQAVSYQQACEATLRTSDNTAANIVLEGIGGP +QGLTGFFRDIGDNRSRLDDIEPKLNQVALGETNNTSHAIALVQSLQRLTFGRVLTTGSQE +QLLTWMKANQVSDNLLRASLPEGWRIADRSGAGKQGDRGIIAVVWPDNTQPVIMAIYIQH +AKADMAQLDQAIAAIGASLF--- +>[subseq from] Beta-lactamase n=1 Tax=Dyella sp. DHG54 TaxID=1920168 RepID=A0A370K6F0_9GAMM +-rQLQRALDALVQRAPGVLGVAVLDLQSGASA-GVHADQAFPMMSVFKAPVAAAVLARVD +GGSLSLDQPVVIHQADVLSGSPSIGAHFHGEFTVGQLLTAAVSQSDNTAVDALIKVVGGP +EVVTAFLRAHGIAGMRVDQGEAGVSRAFLADPRNRSTPEAAVTFLHKLWKGELLSPASTQ +RLLNLMYAQTI-PNRLRAGLPANVRLADKSGTSWIAAYNDIGILSWPDGHVVIVAAFLSD +SPATPAARDALFAGLARDIA--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SL22_9BACT +-----AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD +QGALNLEQIIHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQGSDNNTCDLLFALIGGT +ETVQKDLKEWGISGINVRFTEDEMLRNHDLQYANSSRPSAMNALLRAFDEGKILNKDTQR +LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD +SKDSAPACEKVIASMARWLCTEw +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI001296EC68 +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPARLHAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Serine hydrolase n=1 Tax=Chryseobacterium bernardetii TaxID=1241978 RepID=A0A3G6TL63_9FLAO +--EFKKAIESILANKKADVGVSILTAGTKKEVtQINGNKLLPMLSTFKFPVALAVLHKVE +KGELSLQQKIYIKKEELLEYSPFREKYPEGNLSLEDCIQWMIVYSDNNLTDILLRLIGGP +DYVQNFINS---KDIVIKNDEEDMHKDWDSQFINTITPNEAIRLLEQFYNGKILNKEHTK +WLYTAMLNNATGTKRLKGKLPKDVKVAHRTGTSFTGAINDYGIIELSDKKRIYIAVFVHD +TYETFENSESIIADISKAAYDYy +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD7A3C9 +-dRLRSELTVLANAHPGRVGICVREEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDQAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris CAG:120 TaxID=1263053 RepID=R6B270_9BACE +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHDNEMHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFNLSETEDSMHRNPQKAYANWSTPSEMVRLLKMADEKDLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGIVIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium aquicola TaxID=1682742 RepID=A0A3E0EV58_9FLAO +-nELRKQLKEIIASKNASIGVSIKNIEDKDTL-SINGNLNAPLMSVFKFHIGLTALNLVD +NGKLSLSQKIFIKKEDLHEWSPLRDEYPNGNLTLDQLLRYTVSHSDNNGCDILLELIGGT +KAVQKFINKQGIKDFVIKVNEKEMST-WENLYINTTTPLATTALLEKFYNGKVLKENSTK +YLYTLMAECSRGLSWMKAGLPVGTELAHRTGMSGRAAMNDVGIVKLPNGRHLIISIYLKN +ITETKENTEKILADITKLTWDYy +>[subseq from] Class A beta-lactamase n=1 Tax=Flavobacterium hercynium TaxID=387094 RepID=A0A226H401_9FLAO +-tELRKKIEHLISNKKLTAGISIKRIEDQDTL-SINGNLEAPMMSVFKFHIALTVLDLVD +NGRLKLDQSFFIKKEELLPWSPMREEFPEGNLTLDQLLRYTVSHSDNNGCDILLRQIGGT +ETVQKFINSQGIKDFTIKVNEEEMST-WENLYVNTTTPLATTTLLEKFYKGQVLKETSTK +YLYQIMVETSRGLTWMKAGLPKNTELAHRTGISGTNAMNNIGIFKLPNGQHVILCIYLKN +ISISMKATEKLMADITKAVWKHy +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides stercoris TaxID=46506 RepID=B0NPP4_BACSE +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNKVHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLQQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFNLSETEDSMHRNPQKAYANWSTPSEMVRLLKMADEKNLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGIVIMPGGKKYYIAVFVTD +SSETDEEDAAIIAHISRMVYDE- +>[subseq from] Beta-lactamase n=1 Tax=Muricauda lutimaris TaxID=475082 RepID=A0A3A1NAT8_9FLAO +-eTLRQKIDSITNTKDVIVGVAINGFKTNDTL-SINGQRHYPMQSVFKLPIALVILSEVD +KGNLSLDQKIDIKKSELLPWSPIREKYPEGALTIAEIIEYTVAMSDNVGCDVLLKLLGKP +QVVENYFSSLGFKDFAAKINEETMQSNWELQFLNWTTPIEANKILSTFYKNKLLSQDSYD +FIWNILKGTKVGKNRLKGQLPEETVVAHKTGWSGTAAVNNIGIVFMPNGEYFTISVFVTE +SKEDFKTNEKIISDISKVAWDYf +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter sediminis TaxID=1689985 RepID=UPI001328FED7 +-nQLERKIALLANGEKGRIGVAAIDLATGAQV-SILGDQRFPMASTSKIAIAATFMEGVE +QGRWSLSSEFPLLVPVRSASSRVAPVKRGAHLPASELVELMITRSSNPATDALLAVIGGP +KAVNDWTRRAGIREFQLDRDIATLVRAAHIDERDSASPQAMIDLLAGLYQGKFLSDSSRR +VILGAMERCRTGTRRIPALLPSNAQVAHKTGSLNN-TSSDIGIIEAPDGRAIAVAIYVTG +QG-SRGAREARIAEIARALYEGy +>[subseq from] Beta-lactamase n=3 Tax=Staphylococcus TaxID=1279 RepID=U6EG14_STASC +--------------------MYALNTQNGKEL-SFNENKRFAYASTLKAISSAMLLEQTP +--YNKLDKKIHINKDDIVPYSPVLEKYIGKEITLKKLIEATMLFSDNTANNKIIDELGGY +EQVKTRLIDLGDTTTYPSRKEPDLNFYSPKDKRDTSTPLAYGKTLKKLIADGDLSKANKD +FLLDLMLKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVAFVYPDGQKPIILVIFTNK +DRKDGKPNDKIVSEVAEIVLK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris CC31F TaxID=1073351 RepID=S3YHW0_BACSE +--TLEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLRQKHSSQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYSNWSTPSEMVRLLKMADEKNLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGIVIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] class A beta-lactamase n=1 Tax=Ensifer sp. MMN_5 TaxID=2037902 RepID=UPI000C9C848E +--RLRLELETLADGHPGRVGICVQD-QPKAPV-CVNGAQRFSLQSVMKLVVAAAVMQAVD +EQRIRLDDQITIRREDLSVIQPIADIVARHGTSVRDLVRRAVVASDSAATDVLIARLGGT +KAIQVFLEKAGLTGVRIDRTERELQTAYMKDPRDTATPRGMAAFLYSLASGSLLTAGSTE +FLLTVMSQTTTFPDRLRAGIPPEWGIGHKTGTSQNGVTNDVGILTAPDGRRIAVAAFVAE +SRAGQAERAAVIAAAARAITAAy +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonadales bacterium 12-68-11 TaxID=1970586 RepID=A0A257YJ41_9SPHN +---FEQQLAQLANGARGRIGIAAVDLATGQEI-AVFGDQRFPMASTSKIAIAATYLEGVE +QGRWTLSSEFALRVPVGSRSTAIAPTRDGQVMSAAQLIDLMITRSSNPATDALLKAVGGP +AAVNDWARRAGISEFNLTRDIATLVRAVHVDLRDSATPRAMAQLVSGIYQGKWLSPASRA +VIVSAMERCVTGKGRIRALLPGEVTVAHKTGTLSN-TASDIGVLTTPDGRSLAVAIYVTG +QGG-KAGRDAKIASIARALYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDBE95F +-dRLRSELTVLANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLIIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDQAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter aquimixticola TaxID=2489173 RepID=A0A4T3EXR8_9SPHN +---LERHIASLADGSQGRIGVAAIDLATGQQI-SILGDQPFPMASTSKIAIAATYLEMVD +KGQLSLTSEFPLLLPVRSQFSTAVAPVRNGEMPAHQLIDLMITRSSNPATDALIAAVGGV +DKVNDWARRAGIDNFNLTRDIATLVRAVHIDLRDSSTPAAMVELLSGIYQGRWLSAESRA +VIIDAMERCRTGTRRIPALMPDNVTVAHKTGSLNN-TSSDIGILTGPDGRSIALAIYVTG +QG-TRSNREARIASIARAIYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000D1ED50A +-dRLRSELTVLANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDQAGLQGIRIDRTERELQTAYLKDPRDTAMPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Beta-lactamase n=2 Tax=Erythrobacter sp. EC-HK427 TaxID=2038396 RepID=A0A5E7YFY5_9SPHN +---FEARLAQLADGSEGRIGVAALDLSTGRQI-SIYGDQRFPLASTSKIAIAAAYLEGVD +QGRWSLTAEYPLLVPNSTPLSSARAPVRQGELPAHELIDLMITRSSNPATDALLAAMGGV +GPVNDWMRRAGITEFSLDRDIATLVRRHYIDPRDSATPEAMVQLLAGIYQGRWLSRESRH +IIIDAMERCRTGSTRIPALMPAGVTVAHKTGTLHR-VASDIGIITGPDGRTIVVAIYVTG +QN-SPTDRNARIATIARALYDGf +>[subseq from] serine hydrolase n=1 Tax=Croceicoccus pelagius TaxID=1703341 RepID=UPI0009EDE959 +---LRQNLFAVARPDKGRIGVAAMDLSTGQTV-SILGDQAFPMASTSKIAIAATFLAGVD +AGRYRLDDKYPLMIPVASRSTSVAPVKPGMELTARSLIELMITRSDNTATDAMLKAVGGP +AEVTKWMRSKGFERFRIDRDIATLVRATGADQRDSTPPNEMVRLIAGLYKGEWLSGESTD +VVIGAMTRTVTGSRRIKAGLPSGVDFGHKTGTLNN-TASDVGFVEMPDGRVVVMAIYVTG +QG-GRPQRDARIAEITRTLYAGf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0K0N4E8_ECOLX +------------------------------------------------------------ +-----------------------------GTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAX------- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI0012976700 +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLEGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMAGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides salyersiae CL02T12C01 TaxID=997887 RepID=I9SU85_9BACE +---LKADFDKLLQDKQATVGVAVVS-DGRKTF-TYNNQHHFPLMSVFKFHQALAVLNYLD +RKQLPLTTEILIRKADLLPYSPLREARPEGGMSVGELLRYSVSESDNNACDILFRYIGGV +EVVDKYIRTLGITDFKIEATEEDMHEGFRYQYLNWTTPLAAVRALEKFCTETLFRHSYKE +FLEKIMMETVTGKDKLKAGLPPAIVLGHKTGSSDKAGDNDMGFVRLPDGSRYSIAVFVKD +SKEDDKTNAALIAAISQKVYEYy +>[subseq from] Uncharacterized protein n=5 Tax=unclassified Bosea TaxID=2653178 RepID=A0A653TEF5_9BRAD +--RLDAGIKTIEQSTKGRIGVGLIDLKDRKSW-SYRGAEPFPLQSVFKLPLAIGVLQAVE +AGKLKLDQKITVTRNDLSLHSPLAKAFKGERYPLRELLTRSTAESDNTAADLLLRLIGGP +QALTAILKDGGVTGISVDRYERVFQPATLTDKRDAASPEASIAFLEGLAKGNWLREPAHA +ALLDIMLEAKTGPNRIKAGLPEGARFAHKTGLGPNHATNDIGIVTLPDGRRFAIAAYLAG +AQVGEKEREAAHAAVARLAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Rhizobiales bacterium 65-79 TaxID=1895815 RepID=A0A1M2YZN8_9RHIZ +---LQAGLDALAKRAPATFGIEVRDLRTGKSW-GVNAGKPLPMMSVFKAPVAAAVLAKAD +NGEISLDQPVSITRKDLRGASRIARNFRGDSFTVRQLLEDMVSQSDNTAADRLIALIGGP +QAVTQFLRLKGIEGMRVDLDEGGVEHAFLADPRNRSTPETAADFLQKLWQGKLLSPASAK +RLLDLMYGQTV-PVRLRAGLPAGVRLADKCGTSVTGAFNDIGVLTWPDGHTVIVAAFLSG +SRASREERTKLFADLARMVAARf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000CFFA34D +hdALQATLERFAQAAPGTLGVVVLDLDRPARW-QVNGTLPFPMMSVFKAPLGATVLDLAE +QGKLPLGQRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP +AVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR +RLLGLLRDQTT-PRRLRAGLPPGVSFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA +SRASRAERDRLFADLARAVAS-- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia gladioli TaxID=28095 RepID=A0A2A7SJ89_BURGA +hdALQATLERFAQAAPGTLGVVVLDLDRPARW-QVNGTLPFPMMSVFKAPLGATVLDLAE +QGKLPLGQRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP +AVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR +RLLGLLRDQTT-PRRLRAGLPPGVSFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA +SRASRAERDRLFADLARAVAS-- +>[subseq from] Serine hydrolase n=1 Tax=Deltaproteobacteria bacterium HGW-Deltaproteobacteria-15 TaxID=2013742 RepID=A0A2N2KBT7_9DELT +--RLRSRVESAIPPSQGVVGVSIKHMESGIVV-AVHGDEPFPMASTFKLPLLVELYAKEK +EGAFKWDDLVEISSTDQHLSSGLTAVYDTPGLSIRNLANLMIIASDNSAADICLSKVGGP +SKVTAGMRKIGIHGIRIDRSCQELILRLAADPADSATPDAMVALLERIWQGRAVDPAASD +AMMKTLNRCRTGANRIRGLLPPSTDVAHKTGTLG-GVVNDVGIITLPDNGHVAIAVMSKR +TRAPREQVERVIADIARYAYDYf +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A0D5CAD7_ECOLX +-------------------------------------------------MAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTT--------------------- +----------------------- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X2T7_9BACT +--ALETELRRLAATLPGTVGIAVHHVGTGRLV-TVDADRAFSMARVFKLPVAIAVLRRVQ +TGGLTLETPITIAPEAYYPYSPLRDAKNRAEVTVRDLVETMMVDSDNTAVDVLMARMGGA +DAVNAELRAAGVPDVSVHRTEGEVMAKFLADSRDTATPTALANLLARLDRGEVLDAERTK +ILVGMLDRNKTGGRRFRAGLPAGVRIGDKTGTNPVGTYNDAALVTLPSGARIALVVMTRE +AGDTGAAAEQLMASVARTVYAHf +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter aerius TaxID=1837929 RepID=UPI00130FA0B9 +--SFEQAVARVADGSSGRIGVYAVDLASGREV-SVLGDQRFPMASTSKIAVAAAFMEQVE +RGKYTLTSEFPLMMPVASKFSTARAPVVPGKFQAVDLIEMMITRSSNPATDALLKAVGGP +AVVNDWARRNGISEFNITRDIATLVRARAIDIRDSATPQAMVKLLAGLHQGKFLSASSRR +VILGAMERCRTGTRRIPGMLPAGARVAHKTGTLNN-TASDIGIIQTPDGRSIAVAIYVTG +QG-SKPARDAKIASIARALYDGy +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. 66-12 TaxID=1895714 RepID=A0A1Q3MBV1_9SPHN +-nALSQRIAMIAEGSRGRIGVAAIDLVTGQEV-AVLGDQRFPMASTSKIAIAATFLEGVD +QGRFSLTSEYPLMVPVSSKSSAVAPVKAGTYHTAAELLELMLTRSSNTATDGLLKVVGGP +AAVNDWARRAGITSYNLTRDIATLVRSSHVDIRDSVTPRDMARLLAGLYQGKWLSPASHD +LLISTMEKCRTGPRRIPALLSAEVTVAHKTGSLNN-TSSDVGIVTGPNGHPVAMAIYVTG +QGAR-AKREDRIAMIARELYDGy +>[subseq from] Veb-1 n=1 Tax=Sphingobacterium deserti TaxID=1229276 RepID=A0A0B8SYQ6_9SPHI +-kSLENDIKTFIHDKKAIVAVAIKNGREGDIV-HVHADEKLPMQSVFKFHIAVAMLTEID +KGNFKLQQPIVIKKEDLTPWSPLRDAYPQGTMPLSTVITYMVSQSDNVACDIVLKLLGGP +EVVDQFYKEKGVKDLSIKINEKTMQRNWEAQFKNWTTAEECTDLLKTYFYKKELSAESHQ +FLWTVMKGTETGLKRLKGNLPANTAVAHKTGYSGTEAVHDIGVIYLPNNDPIFISVLVSK +SREDLATNEEIIARIAHMAYDFy +>[subseq from] Serine hydrolase n=1 Tax=Chryseobacterium sp. G0162 TaxID=2487063 RepID=A0A3G6S498_9FLAO +-sELKKAIETILAHKKADVGVSIVTAGTKKEViQINGNKPLPMLSTFKFPVALAVLHKVE +KGELSLQQKIYIKKEELLEYSPFKDKYPDGNLSLEDCIQWMVVYSDNNLTDILLRLIGGP +DYVQQFINS---KNIVIKNDEEGMHKDWDSQFINTITPNEATQLLEQFYTGKILNKEHTK +WLYTAMLNNATGAKRLKGKLPKDVKVAHRTGTSFTGAVNDYGIIELSDKKRIYIAVLVHD +TYETFENSEAIIADIAKAAYNHy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0U5IQE6_9BACT +---PQQDFKELEKKYDAHLGIYVIDTATNKKI-AYHANERFAFTSTYKVLAAGVLLQNYS +--LEQLETVIPYTKDDLVAYSPVTELHTDTGMTLREISEAAVRYSDNTAGNLLFHAIGGP +KGFEKSLRKMGDKTTYANRFETELNTAIPGDKRDTSTAKALAKDLKKLTVGSALPAGKQQ +LLLDWMTDNKTGDALIRAGVLKG------------------------------------- +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B2CD67_KLEOX +-----------------------------------------------KHMLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWYFAD-------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Phenylobacterium sp. CCH9-H3 TaxID=1768774 RepID=UPI00083A02FA +-------ISAIAGAAPASLGVGLSNLESGQTY-TFNGDRRFPMQSVFKLPLAAAVLAEAD +AGRLMLTEPFVLTEEQLSPVSPIAAGWPARRYTAQALFEAMVVDSDNTAADVLMKRIGGP +GAVTAWLTARRVPEVRVDRYERELQPRYMSDPRDTTTPRGMLELLQMLDRQELVSPASTK +RLLELMGRTRRGVGRIRAGLPRDAFLAHRPGTSGSTAHNDVGIFTLADRRSYALAVFLSG +STLDEAGRDRIIAEVARAAL--- +>[subseq from] class A beta-lactamase n=1 Tax=Coxiella burnetii TaxID=777 RepID=UPI000B9545AD +------------------------------------------------------------ +----------------------MTKNHINGGITVSELCAAALTLSDNSAANLLIKKLGGL +TAINAFARSIGDKQFELDRLEPQLNSAIPGDIRDTTTPEAMANSLKRLTLGDILAFPQRI +QLQTWLKNNTTGNAKIRAGVPKDWIVGDKTGSGGYGTTNDIGIIWPPKRAPIVVAIFFTK +NKKGAVSPDSIIERITRILM--- +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia TaxID=32008 RepID=A0A560UVK9_9BURK +hdALQATLERFAQAAPGTLGVVVLDLDRPSRW-QVNGTLPFPMMSVFKAPLGATVLDLAE +QGKLPLGQRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP +AVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR +RLLGLLRDQTT-PRRLRAGLPPGVSFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA +SRASRAERDRLFADLARAVAS-- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium lindaniclasticum LE124 TaxID=1096930 RepID=T0HQ21_9SPHN +---FGKQLASVAEASRGRIGVAAIDLSSGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD +KGKWSLSSEFPLMVPVPSASSAIAPVRPGTYMSARQLIEIMITRSNNYATDALLKVVGGP +SAVNAWVRRTGIEEWHIDRDIATLVRARVVDKRDSATPIAMAQLLSGIYQGKWMSKQGRD +VLLGAMSRTVTGKRRIRAGLPAEVSVSHKTGSLNN-TSSDIGIIETPDGRAYAVAIYVTG +QG-TRPNREARIASIARTIYEGy +>[subseq from] Beta-lactamase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E7UD97_9SPHN +--RARAQLVDIEKRSGGRLGVALIDPAGEVLL-SHRGEERFAMCSTFKTLLAGMVLSGET +--GLEQEDRLTIDPAEVEGHAPFTRSRFEEGMTVGDAAQNIVTVSDNGAANLLLDEVGGP +RGLTEWIRALGDDVTRLDRRELALNENAADDPRDTTSPLAFGETYRRVLSDDVLDASGRE +RLAQWLEASETGLNRLRAGMPGDWRVGDKTGYCAAVEINDVAIFDPAGGGWYTLVFFLDR +PREAGAFADALGAEVGAIAAD-- +>[subseq from] Class A beta-lactamase n=1 Tax=Asaia sp. W19 TaxID=2067395 RepID=A0A433WYQ0_9PROT +----------YEKGCGGRLGVHIFCPETGAAL-TWRGNERFLMCSSFKASLVACVLARCD +RDEDELTTHLPFLDSDFTAWAPVARKNRDAGLSLAALCAGAVTASDNVCANMLLRHIGGP +AALTHFWRESGDEITRLDAYEPELNRPSADAAANTTSPVAMARTLHRLVHGTLLHPNSAA +LLRNWMISCNTGTHRLRAGLPPHWISGDKTGNNGQDIAADIAFAAPDPGKSLIIAVYTAG +GTPDETRFRNVFHELGAL----- +>[subseq from] Beta-lactamase (Fragment) n=6 Tax=Bacteria TaxID=2 RepID=C7F8X0_ECOLX +-------------------------------------------CSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKT------------------------------ +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Bosea sp. F3-2 TaxID=2599640 RepID=A0A5C1B535_9BRAD +-aKLDKEIIAIEEQAKGRLGVALVDLKDRKQW-SYRGAETFPLQSVFKLPLAVAVLQQVE +AGKFKLDQPITVTRQDFSLNSPLAKAFKGERYPLSELVRLAAGQSDNTAADLLMREIGGP +QVVTKMLRDGGITGISIDRYERQFQPKALKDKRDAATPEASALFLEAFAKGNWLRPAHTA +FIEKIAAEMKIGAERIKAGLPAGSRLAHRTGLGLNHASNDIGIATLPDGRRFVIVVYLAG +SRADANERDAAHAAVARLAVS-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SV74_9BACT +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGEILQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFNLSETEDSMHQNPQKAYANWSTPSEMVRLLKMADEKDLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI000CD29E66 +-----KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNTP +--TSELNKKIVISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI +KGFQQALIHRGDHITNPQRLEPDLNLYDPQSTDDTTTPKRAATTLNHLLQSENMSKANLE +LLKHTMIHNETGDTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK +SDKDAKPDDKVIQTAAETAIK-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Alistipes sp. cv1 TaxID=1622071 RepID=UPI000C77626C +---LVRQIDSVLSRYRATVGVTVLS-NRDEIV-AANDSILFPLMSVFKFHIALAVLDRMD +RNRTRLDSVVRIKASDMHPYSPLRERHPGRDITIAELLRYSVAHSDNNACDILLEYAGGP +EVVEKYVRGLGIENTFISASEKTMHDRIENQYLNRSTPTATARLIETFFENRLFASKYKK +FLIRIMTETSTGQDKLKGLLPPDCTVGHKTGSSDRTADNDAGFVLTPDGKRYYIAVFVSD +SQEDDPTNASIIARISAIVYD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=D1KRK6_ECOLX +--------------------------------------------------------ARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVSLLGP-------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Francisella noatunensis TaxID=657445 RepID=UPI000B58CC99 +--TLDDSFKNLEDEYHGKIGIYTLNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM +QDKGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL +EKLNKLVAKLGDKDTIIKNDEPKINHTKPDSNINKTTPKAITQDIYNLAFGNILDKKHRE +IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQNKPPFALSILYTN +TSVKALSNEKIIQQASKLTA--- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A1W6AL12_ECOLX +-----------------------------------------------KVMAAAAVLKXSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYG------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Sphingomonadaceae (miscellaneous) TaxID=122612 RepID=UPI0010F435A6 +---LDDRLFQIWKAFPGKTGIAVQRIDGEWTL-TQRGNELFPQQSVSKLWVALAVLDAVD +NGRLRLDQNVRIGPEDLTLHQPIAGRVQAQGMTVRELIETAITQSDNTANDSLLRTVGGP +DAVRRFIDKKDLGAIRFGPGERLLQAAYRADPPDGASPAAIANALTRLARGALLSPESTQ +YLLGVMTRTKSGPQRLKAGLPAGWTFLHKTGTGQTVGYNDIGIATAPDGTRYAIVVLMGE +ASSPVPARMATMQSVSRAVAEY- +>[subseq from] Class A beta-lactamase n=1 Tax=Flavobacterium sp. IR1 TaxID=2026304 RepID=A0A270QJE2_9FLAO +-tELRKKIEHLISNKKLTAGISIKRIEDQDTL-SINGNLEAPMMSVFKFHIALTVLDLVD +NGKLKLNQSFFIKKEELLPWSPMREEFPEGDLTLDQLLRYTVSHSDNNGCDILLRQIGGT +ETVQKFINSQGIKDFTIKVNEEEMST-WENLYVNTTTPLATTTLLEKFYKGQVLKETSTK +YLYQIMVETSRGLTWMKAGLPKNTELAHRTGISGTNAMNNIGIFKLPNRQHVILCIYLKN +ISISMKATEKLMADITKAVWKHy +>[subseq from] Beta-lactamase n=1 Tax=Microscilla marina ATCC 23134 TaxID=313606 RepID=A1ZTJ7_9BACT +---LKQKIHQVFKGKSATVGVAIRGSNSADAI-SINGNKRLPMQSVFKYHLALAVLHQVD +QGKFSLNEKIAITQKMVNAWSPLRKKYPNGALTLAEILRYTVAWSDNLGCDVLFKLIGGT +KVVESYVHKIGVKDIAIVHNEIVMQAKWKHQYENWTTANAANQVLQLFFEDNLLSTKSYN +FLLDVLKGTKTGKKSIRGLLPKDAVVAHKTGHSGTGAVNDIGIVFLPDNSYFYVSVLVSN +SLESDATNQKIIADIAKLTWDYf +>[subseq from] Serine hydrolase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=A0A2W4SKC3_9RHIZ +--RLDREIAAIEKQSQGRLGVALLDLRDRKTW-SHRGSESFPMQSVFKLPLAIAALQAVE +AGRFKLDDRITIRRSEFSLHSPLAKAFKGESYALRELIRLTAAESDNTAADNLMRRIGGP +KVVSDMLRAGGIVGISVDRYEREFQPASFKDKRDTASPSASVLLLEAVAQGNWLRDPSHN +SLIKHMLDNAGGRERVRAGLPAGSRFAHRTGAGLNHATNDIGLVTLPNGRVFAIAVYLAG +SRADAKTREAAHAAVAKAAV--- +>[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia subsp. philomiragia (strain ATCC 25017) TaxID=484022 RepID=B0TXT1_FRAP2 +--TLDDSFKNLEDKYHGKLGIYTVNTDDKTNI-SYNQNYHFPICSVFKFLLVGAVLEYDM +QHEGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL +EKLNKLVAKLGDKDTIIKNDEPKINYTKPDSNINKTTPKAITQDIYNLAFGNILDKKHRE +IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQNKPPFALSILYTN +PSVKAPSNEKIIQQASKLTA--- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Paraprevotella xylaniphila TaxID=454155 RepID=UPI001032D1A8 +--DLQEQLRRMVADKKAQVGIAVI-LDGRDTL-TVNNDVRFPMMSVFKFHQALAVADACG +QRGVSFDTLVHVRPDDLHPYSPLRDKYPDGNLSVGELLKYTLHLSDNNACDILFRVFGGP +AATDEYLRSMGLRDFAIEVTEDDMHRNLADCYRNWTTPLEAVRLLEWLVSGKAAKGAYRD +FIEQTMISCQTGRDRLPAPLATKAVIGHKTGTGDRNGTNDIGFVFLPDGHRYSIAVLVRD +SEESEQATARVIADISEAVYRY- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. KEM-5 TaxID=2486356 RepID=A0A5S3P1P6_9SPHN +--ALDRRIAELAEGSNGRIGVAAIDLATGQVV-KVLGDQRFPMASTSKIAIAATFLEGVE +QGRWSLTSEFPLLMPRSSASSRVAPVYEGQYMPARELIEIMITRSNNYATDALLRVVGGP +ERVNDWARRNGLSEFSIDRDIATLVRANHIDLRDSATPMAMVQMLGGLYQGKYLSADSRR +VLLGAMSRTRTGKRRIPAMMPAGVRVSHKTGSLNN-TSSDIGILEMPDGRAIALAIYVTG +QG-TRLNREAKIAAIARAIHDGy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Kluyvera georgiana TaxID=73098 RepID=A0A3S7Q8J3_9ENTR +------------------------------------------------------------ +------NQRVEIKLSDLTNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +GEVTAFARAIGDRTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRHLTLGNALGETQRA +QLVTWLKGNTTGAASIQAGLPKSWVVGDKTGSGDYGTTNDIAVIWPQGRAP--------- +----------------------- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Empedobacter brevis TaxID=247 RepID=UPI00132016E4 +-eRLRTEINQIISSKNLTAGISLKNIENKDTL-SINGNQMMPMMSIFKFHIALTVLHEVD +QNKLQLNQKFFIKKRDLLPWSPILDDFPEGNLTLDQLLRYTVSHSDNNGCDILLKIIGGT +KIVQNFIHKQGIKDFVIKVNEQEMQK-WDNLYINTTSANATAKLLEKFYTNKVLKKNSTT +YLYQLMVETSRGSTWMKAGLPANTELAHRTGISDTNAMNDIGIIKLVDGKRIILSIYLKN +ITEERAETEKVMADITKAVWNYy +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=A0A412T0Z3_BACSE +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGEI +GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYSNWSTPSEMVRLLKMADEKNLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGIVIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] class A beta-lactamase n=1 Tax=Legionella saoudiensis TaxID=1750561 RepID=UPI0007311119 +--ALAKKIRDIEKKSHIVMGITAIHIEKNQII-THNSNQRFFMASTIKLPIALAFLHLVD +QKKESLNRMIKLSTKNSVPGSGYLHHIFEKKISLQQILKYTLINSDNSASDSLLNAAKGP +EAVKKRMAALGFKDIQINRSIKEMFVRFENDSRDTTTPNDMAKLLVKVYKKQALSESSTQ +LLMKIMEQCRTGRSRIRGLLPPGVKVAHKTGTWSYRFVSDVGIITLPNKGHIAIAVYVKS +QSASDYPRSRAIALASRAIYDHf +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma sp. I-24 TaxID=2666025 RepID=UPI00138E8BA8 +--RLEQELVRLSDISGGKVGICAVHLESGKTI-SQNGKDHFPMASSYKVAIATQLLSRVD +SGSITLDQLIPITKNDLHPGSGMLS-----PLSVRSLLELMLLISDNSATDVCLRLAGGP +DAVNACMKRLGIDGLQVNRPTAWLIAAFENDIRDTSTPEAMTLLLSKLYTQSILKSDSKA +LMLDIMKRCETGLARLKGALPPDTEVLHKTGTIGL-TASDVGLITLPDNGHVAISVFVKS +SKKDGALRERAIAEVTRTIYDYf +>[subseq from] Beta-lactamase n=1 Tax=Kozakia baliensis TaxID=153496 RepID=A0A1D8UWK6_9PROT +----KQLLSEIEKKLGGRVGVSAVDTKTGLAL-QWRGSERFVMHSVFKWLLSAYLLHCSD +TGSRPLQTSVVIKTSSIVGHSDQTKPFAGTAVTIETLCFWMMSTSDNGAANTLLDVIGGP +SVLTSWLRSLGDTTTRQDTYEPGPTEG-SIDPRNTTTPDAMLALTQKIWMGSVLSPGSRE +TLLAWLQSSAVGGRRLRAGVPSSWVEGDRTGTGDPGVADDVAIFWPDGHKTILVTSFLEG +STNSLARLESAQASIGQILANLf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDA152D +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIETVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATISAAARAITAAy +>[subseq from] Beta-lactamase n=2 Tax=Algoriphagus TaxID=246875 RepID=A0A0P7Y425_9BACT +---LLTQIEQIVSDKDAIVGVSIIGNNGKDTL-SLHGNMRFPMQSVFKFQVALAVLGEID +QGNISIDQKIEIEKDEFLPWSPLRDAYPNGGFSVEILIQYCVSHSDNSACDILIQLIGGP +KTVESFIKKTGVEDLQIEFNEEKMQSKWENMYHNWTTPNAASETLKLFYENKLLSKVSYD +FFWKTMKETTTGKNRIKGLLPIETIVAHKTGWSGTAALNDVGIVFLPNNEYFILSIFITE +SRENFDTNEKIIAEIAKAAYDFy +>[subseq from] Beta-lactamase n=2 Tax=Novosphingobium TaxID=165696 RepID=A0A158SRP9_9SPHN +--QFEKQLASVAEASKGRIGVAAVDLATGRTI-EVLGDQRFPMASTSKIAIAATFLAGVE +KGKWSLTSEFPLMVPVASASSPVAPVRPGAYLSARELIEQMITRSNNYATDALLKVVGGP +KAVNDWVHNAGIEDWHLDRDIATLVRAQVIDKRDSATPLAMVKLLNGIYDGKWMKAESRD +VILGAMSRCRTGRRRIPAMMPDGVTVSHKTGSLNN-TSSDVGIIQTPEGHAFAVAIYVTG +QG-SRPNREARIAQIARAVYDGy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5L0A1_9BACT +-sELKNRIDSLLNSKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=G3JXZ1_KLEPN +-------------------------------------------------MAAAAVLKKCE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTK--------------------- +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Dyella thiooxydans TaxID=445710 RepID=A0A161IV29_9GAMM +-dELQARLQALSRQAPGRLGVTVLDLRDGHAW-RTGADRAYPMMSVFKAPLGAALLARVD +AGTLSLDRQVTITRADLRHRSAIADRFHGEAFTVRELLVAAVADSDNTAADALLPLAGGP +AGVTAFLRSHGIDGLRVDRGEGAIYHAYMAGPRDTSTPDAAASFLRQLWQGELLSAPSTR +LLLDTMTHTPP--FRIEPGLPKSVRFAHKGGTSATAAFNDIGVIAWPDGRAVVVAAFLTG +STQSAKERNALFAELGRVVVR-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SPH0_9BACT +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLRQKHSGQDILLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYSNWSTPSEMVRLLKMADEKNLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. AF29-11 TaxID=2292928 RepID=A0A3A5X1S1_9BACE +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000BD3AD4B +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSLVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLL----------- +------------------------------------------------------------ +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A6B1AGF4_9BACT +---LLAEIERLAPSSGGTVGVGAVHIETGRAV-WFNEDERFPMASTYKVPIAVQLLSRVD +RGEITLADMVELEPGDIHPGSGTISNLFDDPLSLRNLLELMLLISDNSATDLTLTAAGGP +DAVNARMSELNVDGLSVNRPTSVLIGAFSTDLQDTSTPRAMAHLLAMTWAGKALGSKNTE +VFKDVMLRVQTGTGRIKGVLPPGTPVGHKTGTIG-GTTNDVGYIYLPDDGHVITVVFVKD +SERPVPAREATIAQISRAIYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Fluviicola sp. RIFCSPHIGHO2_12_FULL_43_24 TaxID=1798019 RepID=A0A1G0CC29_9FLAO +--DLKAELEQFLSQCRATAGVSVKVLEDGEAF-TINDTVLHPTLSVYKFPLALAVLHKVD +KGKLKLDQTVHITKEMLHPWSPYRDVHPEGNATISELLAYSVSRSDNNTTDILFDLLGGP +AKVHQYIAGLGIKDMMIAANEYEMGEE-NRLYDNWSKSAAMVDLLGKFYSKKVLSEENTQ +LLVKLMTDTPTGINRMKGLLPATAIVAHKTGTSGTNAVNDVGIITLPNGKHIAIAVFVTD +SKESFETNEYIIAHIAGAVWNHy +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD221AD +-dRLRSELTVLANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAGTDVLISHLGGT +KAVQAFLDQAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Beta-lactamase class A n=1 Tax=Bosea sp. CF476 TaxID=2135474 RepID=A0A318XH89_9BRAD +--KLDAGIKTIEQSTKGRLGVGLIDLKDRKSW-SYRGAEPFPLQSVFKLPLAIGVLQAVE +AGKLKLDQPITVTRNDLSLHSPLAKAFKGERYPLRELLARSTGESDNTAADLLLRLVGGP +QALTAVLKDGGVTGISVDRYERVFQPATLTDRRDAASPDASIAFLEGLAKGTWLRDPSHA +ALLDIMLEARTGPNRIKAGLPAGARFAHKTGLGPNHATNDIGIVTLPDGRRFAIAVYLAG +AQVGEKEREAAHAAVARLAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Bosea sp. FBZP-16 TaxID=2065382 RepID=UPI000C30877B +--RLDSGIKTIEQGTKGRIGVGLIDLKDRKSW-TYRGAEPFPLQSVFKLPLAIGVLQAVE +AGKFKLDQKITVTRNDLSLHSPLAKAFKGERYPLRELLTRSTAESDNTAADLLLRLIGGP +QALTTLLRDGGVTGISVDRYERVFQPATLTDKRDAASPEASIAFLEGLAKGNWLRDPANA +ALLDIMLEAKTGPNRIRAGLPKGARFAHKTGLGPNHATNDIGIVTLPDGRRFAIAVYLAG +AQVGEKEREAAHQAVAKLAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI0009A1A77B +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATPR-------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. B04 TaxID=1945860 RepID=A0A1V3QJP1_9GAMM +--RLQRTLAALAQRAPGTLGVAVLDLQSGVEA-GVNAGQAFPMMSVFKAPVAAAVLSRID +AGKLSLQQQVIVTRADVLNGSPSIGAHFRGEFTVEQLLQAAVSESDNTAVDALLKLVGGP +QVVTAFLRAHGIAGMRVDLDEAGVGRAFLAAPTNRSTPDAAVSFLRKLQGNELLTPASTQ +HLLDLMAAQTI-PNRLRAGGPHGVRFADKTGTSDTAAFNDIGIFTGPDGHTVIVAAFLTD +SPASQAQRDALFADIARAAVA-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SQ41_9BACT +---LKADFDKLLQDKQATVGVAVVS-DGCKTF-TYNNQHHFPLMSVFKFHQALAVLNYLD +RKQLPLTTEILIRKADLLPYSPLREARPEGGMSVGELLRYSVSESDNNACDILFRYIGGV +EVVDKYIRTLGITDFKIEATEEDMHEGFRYQYLNWTTPLAAVRALEKFCTETLFRHSYKE +FLEKIMMETVTGKDKLKAGLPPAVVLGHKTGSSDKAGDNDMGFVRLPDGSRYSIAVFVKD +SKEDDKTNAALIAAISQKVYEYy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides salyersiae TaxID=291644 RepID=A0A5M4ZAC3_9BACE +---LKADFDKLLQDKQATVGVAVVS-DGCKTF-TYNNQHHFPLMSVFKFHQALAVLNYLD +RKQLPLTTEILIRKADLLPYSPLREARPEGGMSVGELLRYSVSESDNNACDILFRYIGGV +EVVDKYIRTLGITDFKIEATEEDMHEGFRYQYLNWTTPLAAVRALEKFCTETLFRHSYKE +FLEKIMMETVTGKDKLKAGLPPAVVLGHKTGSSDKAGDNDMGFVRLPDGSRYSIAVFVKD +SKEDDKTNAALIAAISQKVYEYy +>[subseq from] Beta-lactamase class A n=1 Tax=Bosea lupini TaxID=1036779 RepID=A0A1H7SG78_9BRAD +--KLDAGIKTIEQGTKGRIGVGLIDLKDRKSW-TYRGGEPFPLQSVFKLPLAIGVLQAVE +AGKFKLDQPITVTRNDLSLHSPLAKGFKGERYPLRELLTRSTAESDNTAADLLLRLIGGP +QALTALLRDGGVTGISVDRYERVFQPATLTDKRDAASPEASIAFLEGLAKGNWLRDPANA +ALLDIMLEAKTGPNRIRAGLPKGARFAHKTGLGPNHATNDIGIVTLPDGRRFAIAVYLAG +AQVGEKEREAAHQAVAKLAVE-- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=A0A412JR08_9BACE +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVQECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRTYSIAVFVKD +SEENSQVNNKIIADISRIVYEY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces rubellomurinus (strain ATCC 31215) TaxID=359131 RepID=A0A0F2T9M0_STRR3 +--DVGRRLAELEQQHGGRLGVYARNLRTGRTV-RHRADETFPICSVFKTLAVAAVLRDLD +HDGEFLARRIHYTVDDVKNGAPVTGKNLANGMTVGELCAAAIDQSDNTAGNLLLRELGGP +TAVTRFCRSIGDRVTRLDRWEPDLNTAEPDRTTDITTPHAIARTYRRLVLGHALPPAQRR +RLTDWLLANTTS------------------------------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudoalteromonas phenolica TaxID=161398 RepID=UPI001375F287 +-------------------------------F-SFNGDSKLPMQSVFKFHIAAAVLSEVD +KGKWSLEDKIKITPNDLDNWSPIRKKYPTGTLTLSEVIRYTVSVSDNVGCDILLSMLGGP +KKLEDYLHQSGIKDIAVIYNEENMQKVWQRQYENWTTANAANTALRQFYIKNLLSDKSHQ +FLWDVMKGSKTGRKTIRAGVPKDIQVAHKTGHSGTGAQNDIGIVFLPSGQHYYISVLVSD +SYETSETNQNIIAKISELTWQFf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. CAG:189 TaxID=1262737 RepID=R5JPT4_9BACE +---LKADFDKLLQDKQATVGVAVVS-DGCKTF-TYNNQHHFPLMSVFKFHQALAVLNYLD +RKQLPLTTEILIRKADLLPYSPLREARPKGGMSVGELLRYSVSESDNNACDILFRYIGGV +EVVDKYIRTLGITDFKIEATEEDMHEGFRYQYLNWTTPLAAVRALEKFCTETLFRHSYKE +FLEKIMMETVTGKDKLKAGLPPAVVLGHKTGSSDKAGDNDMGFVRLPDGSRYSIAVFVKD +SKEDDKTNAALIAAISQKVYEYy +>[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A127SML6_9BACT +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLRQKHSGQDILLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYSNWSTPSEMVRLLKMADEKNLFAPVYRD +FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVITPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013A562AA +-----------------------------------------------------AVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KEPTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGTG--------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI00101C5D53 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAALLQ-------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Alistipes sp. dk3624 TaxID=2662363 RepID=A0A5Q0PZR7_9BACT +---LVRQIDSVLSRYRATVGVTVLS-NRDEIV-AANDSILFPLMSVFKFHTALAVLDRMD +KNRTPLDSVVRIKASDMHPYSPLRERHPGRDITIAELLRYSVAHSDNNACDILLEYAGGP +EAVEKYVRGLGIENTFISASEKTMHDRIENQYLNRSTPTATARLIETFFENRLFASKYKK +FLIRIMTETSTGQDKLKSLLPPDCTVGHKTGSSDRTADNDAGFVLTPDGKRYYIAVFVSD +SQEDDPTNASIIARISAIVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Flavobacteriaceae bacterium TaxID=1871037 RepID=A0A348XZ72_9FLAO +-eSLRTEINQILSSKNLTAGISLKNIENKDTL-SINGNQMMPMMSVFKFHIALAVLHEVD +QNKLQLNQRFFIKKEDLLPWSPILEDYPEGNLTLDQLLRYTVSHSDNNGCDILLKIIGGT +KTVQNFINKQGIKDFIIKVNEQEMQT-WDNLYLNTTSANATTKLLEKFYATKVLKKNSTT +YLYQLMVETSRGLTWTKAGLPENTELAHRTGISDTNAMNDIGIIKPINHQPIILSIYLKN +ITEERTETEKVITDITKAVWNYy +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. HN-Y73 TaxID=2320269 RepID=A0A420ELM3_9SPHN +---LEQKVALLANGEEGRIGVAAIDLSSGHEI-AILGNQRFPMASTSKIAIAATFLDGVD +KGKLSLTSEYPLMIPVSSKSSKVAPVRKGQYLSARRLMELMLTRSSNSATDALLAALGGP +DVVSKWVHSTGITDFQLSRDIATLVRVAQIDPRDSATPLAMVQLLKGLYQGEWLSEKSRR +FLIDTMEQCRTGRRRIPALMPEDVTIAHKTGSLHN-TSSDIGILTAPNGKSYAVAIYVTG +QG-TRANREAKIAHIARAIYDGy +>[subseq from] Beta-lactamase class A n=2 Tax=Nitrospirillum amazonense TaxID=28077 RepID=A0A560K8P7_9PROT +---LQARLDRLAHEFPGRAGIAVRDGLTGAEA-GVKARERFPEQSVFKLTVAIALLDLVD +HGRMDLAQKVTLYPRDRSVWQPLAKNITPAGTTLDDLMARMVADSDNVAADTVLRLIGGP +AVVQAALTARGLDGIRVDRDERHLQSAYLSDPRDTAQPATMALLLERLDKGELLSPASTR +RLLDILDHTTTQPNRLKAGLAAGWTVAHKPGAGPTLANNDVGLMTAPDGHRYAVAVYVAS +VQGPRERADAFIAGVARAVVESw +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A412N6N1_BACVU +-sKLETQLKQAIKDKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRTYSIAVFVKD +SEENSQVNNKIIADISRIVYEY- +>[subseq from] class A beta-lactamase n=1 Tax=Gluconobacter cerinus TaxID=38307 RepID=UPI000C074231 +-----ERLQAIERASGGRLGVFVLDTGSGQSV-GWRADERFCHCSTFKLSLAAMALRESD +ANRLDLAETLTFSRADIVGYSPVVERNLAKGLPIITLVEAVQVTSDNAAANVLMRRLGGP +SAMIRFRREIGDNKSRLDGYEPAINVIAPDTEENSTTPRAMAETVRRIVLGDVLSSLSSD +RLRGRMAVTQSGLQRIRAGIPASWRGYDKTGTGMGNKTNDLAVLVPPDRSSLVVIGYFEN +PL--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=A0A2N8HEF9_9BACT +-----ATVQKLAHSLEARVGMAAVMLDTGETV-SIGDEAAYPMQSVFKFILALSVLKQVD +EGKLDLEQIIHIRPEQLLKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT +GTVQKDLKEWGISGINVRFTENEMLRNHDLQYVNSSRPSAMNALLRAFDEGKILNKDTQR +FLWDIMAGCSTGATRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD +SKDSLPACEKVIASMARWLCTEw +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. HN-E23 TaxID=2488860 RepID=A0A3N5D9E4_9SPHN +-nQLELRIAQLAEGSEGRIGVAAVDLATGQTI-SILGDQRFPMASTSKIAIAATFMEGVE +QGRWSLSSEFPLLWAVRSQSTRVAPVREGEYLSARRLIELMLTRSSNQATDALLKAIGGP +SAVNDWAHRAGLSEFSLDRDIATLVRATFIDERDSASPETMVQLLAGLYQGRWLSQASRE +FIIDTMERCRTGTRRIPAMMPGGVTVAHKTGSLNN-TSSDIGILTSPDGRAIALAIYVTG +QG-SRLARERRIASIARGIYDGy +>[subseq from] Uncharacterized protein n=1 Tax=Bosea sp. Root483D1 TaxID=1736544 RepID=A0A0Q9ICQ9_9BRAD +--RLDSGIKAIEQSTKGRLGVGLIDLKDRKSW-SHRGAEPFPLQSVFKLPLAIGVLQAVE +AGKFKLDQKITVTRNDLSLHSPLAKAFKGERYPLRELLARSTGESDNTAADLLLRLIGGP +QALTAILKDGGVTGISVDRYERVFQPATLTDKRDAASPEASIAFLEGLAKGTWLRDPANA +ALLDIMLEAKTGPNRIKAGLPAGARFAHKTGLGPNHATNDIGIVTLPDGRRFAVAVYLAG +AQVGEKEREAAHAAVARLAVE-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI000D1C54E1 +-----KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNTP +--TSELNKKIVISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI +KGFQQALIHRGDHITNPQRLEPDLNLYDPQSTDDTTTPKRAATTLNHLLQSENMSKANLE +LLKHTMIHNETGDTLIKAAISKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK +SDKDAKPDDKVIQTAAETAIK-- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A3N7GJ16_9FLAO +-qNLKRDIRKITRGKKATVAVAVRSIDRPELHyGLNGGLHVPLQSVFKFHIAMAVLADVD +RGRFYLSQKIPVKASELREWSPLKEKYPIGDIPLIELLTYTVAQSDNNGADILIRLIGGP +EKVQAFINGKKITDFNIAGGEAYMAENWNNQFNNWSTANSVTETLIRFYNGDLLSPDSTE +FLYDTLVSTTTGKNRLIAGLPTEAVLAHKTGSSATAAVNDAGLVVLPDGRSYAISVFVTD +SKESEAVNEKVIADISKAAYQYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL41_ECOLX +-----------------------------------------------KVMAAAAVLKQSX +XQKQLLNQPVEIKPXDLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRXLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYG------------------------ +----------------------- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseolinea flava TaxID=2059302 RepID=A0A364Y210_9BACT +--ALKSKISSIVKSIDADIGVSMFHVEKKDTL-SLQGTKHYPMQSIYKFHLALAILEQVD +KGNIKLEKKVRIYPDQYFKHSPIIKTYPEGNLSVTQLLEYTIIESDNLGCDLLFDLIGGP +EKVNHFIHTLRIKDVSILNTEREMHVTPDLQFQNWTTPIAMSTLLREFYLRKVLQATTHD +FLWTTLSKTSVGPRRIKGLLPSGTVVAHRTGTGDRDAVNNAGIIVLPNGDHVVLSVFVTH +LRGEIKDGESAIAEIAKAVYDHy +>[subseq from] serine hydrolase n=1 Tax=[Scytonema hofmanni] UTEX B 1581 TaxID=379535 RepID=UPI0004985F33 +--SLKAAVQNLALASNLTPGVFLVDLNSGGYV-DINAGASFPAASTIKVPILVALFQDVD +AGKIRLDEILTMQQDMVAGGSGIQYKPVGTQFTVLELATKMITISDNTATNMLIAKLGGI +DALNQRFRSWGLTTTAIRNKLPDLEGT------NTTSPKELGNLLAMVNQGNLVSMQSRD +RLLDIMRHTER-DTLLPSGLGAGATVAHKTGDIGT-MLADAGLVDMPNGKRYIAAVMIQR +PNND-PRAEKLISAISSTAYQQf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides oleiciplenus TaxID=626931 RepID=A0A3E5BLR2_9BACE +--GLEQQIEQVLKDKKATVGVAVLANDTIIA--LHNNQIHFPLFSVFKFHVALAVLDKMD +KEHVSLDSIMEIKAAQMLPYSPLRQKFPDQDISLRELLEYSISLSDNNACDVLIDYAGGI +EKVNSYIKSLGLKDFNLAANEDLMHRDVATQYQNWSTPEAVVRLLDIADKQTLFATEYKD +FLWQILKETSTGTDKLKGQLPPDVIVGHKTGSSDKTADNDAGFIILPDGREYYITVLVME +SQENDQENAAIIARISKIVYD-- +>[subseq from] Beta-lactamase n=6 Tax=Bacteria TaxID=2 RepID=A0A127T508_9BACT +-sELKNRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1R774_9ZZZZ +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRR------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Luteibacter yeojuensis TaxID=345309 RepID=A0A561H389_9GAMM +--RLHETLERLADEAPGVLGITVVDLDTHART-RVNADRAYPMMSVFKPPVAAAVLAQVD +AGHMSLDEEVTIRRGEVVDGSAVPAHFVGDRFTVEQLLEAAVADSDNTAVDALLRRLGGP +RNVMTYLHAHHVDGMRIDLSEGDVSRAYLKDPRNRTTPDAAAVFLEKLWAGELLSSESTK +RLLDLMYRQTT-PNRMRAGLPADVRFADKCGTSYTAAYNDIGIVTWPNGHTVVVAAFLTA +SRADKPARDALFAKLGKALVE-- +>[subseq from] Beta-lactamase n=1 Tax=Paraprevotella xylaniphila YIT 11841 TaxID=762982 RepID=F3QPU2_9BACT +--DLQEQLRRMVADKKAQVGIAVI-LDGRDTL-TVNNDVRFPMMSVFKFHQALAVADACG +QRGVSFDTLVHVRPDDLHPYSPLRDKYPDGNLSVGELLKYTLHLSDNNACDILFRVFGGP +AATDEYLRSMGLRDFAIEVTEDDMHRNLADCYRNWTTPLEAVRLLEWLVSGKAAKGAYRD +FIEQTMISCQTGRDRLPAPLATKAVIGHKTGTGDRNGTNDIGFVFLPDGHRYSIAVLVRD +SEESEQATARIIADVSEAVYRY- +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. 7_F195 TaxID=2258963 RepID=A0A3D9BAE2_9FLAO +-tTLDQKINIITKDKKATVGISVVGFDHHFKY-SKNGDLKLPMMSVFKFHIACTALDLVD +HGKLSLDQKVFIKKSDLHEWSPFRDQHPKGNASLREVIDYTVALSDNNLCDVLLNLIGGT +KAVQQFMNSRGVKNFQIRHNEHDMAKGWDSLYENYSTVNSITEVLKKLHYGKLLSKNSTD +DLIQMMLGTKTGMNKLVEQLPKNTPVAHKTGSSGKRAENDMGIVTLPNGKQYAIAIFVSN +STETDATNCKIISDISKTVWDDf +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2D6EA9 +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAERNQQI------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides oleiciplenus TaxID=626931 RepID=A0A1Q6GSH6_9BACE +-kELEQQIGQVLKDKKATVGVAVLANDTIVA--LHNNQIHFPLFSVFKFHVALAVLDKMD +KGHVSLDSIMEIKAAQMLPYSPLRQKFPDRDISLGELLKYSISLSDNNACDVLIDYAGGI +DKVNSYIKSLGLKDFNLAANEELMHTNVATQYQNWSTPEAVVRLLNIADKQTLFAAEYKD +FLWQILKETSTGTDKLKGQLPPDVIIGHKTGSSDKTADNDAGFIILPDGRKYYITVLVME +SQETDRENAAIIARISKIVYD-- +>[subseq from] Beta-lactamase n=2 Tax=Erythrobacter nanhaisediminis TaxID=604088 RepID=A0A1I5L686_9SPHN +-nALEQTIAELADGSKGRIGVAAVDLSTGKTV-SVLGDQLFPMASTSKIAVAATFLEGVE +KGKWSLTSEFPLLLPRRSASSPRAPVYEGQYMKAIDLIEIMITRSSNPATDALLRVVGGP +EAVNDWMRRQGIDEFSIDRDIATLVRAQHIDPRDAATPKAMLELLTGLYQGKYLSSESRR +VLLGAMSRTRTGKRRIPALMPASVKVSHKTGSLNN-TSSDVGILETPDGRAVAVAIYVTG +QG-SRLNREAKIAQIARALHDGy +>[subseq from] class A beta-lactamase n=1 Tax=Francisella philomiragia TaxID=28110 RepID=UPI0005A577C1 +--TLDYSFKNLEDKYHGKIGIYTLNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM +QDKGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL +EKLNKLVAKLGDKDTIIKNDEPKINHTKPDSNINKTTPKAITQDIYNLSFGNILDKKHRE +IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQNKPPFALSILYTN +PSVKAPSNEKIIQQASKLTA--- +>[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium aurantiacum TaxID=2116499 RepID=UPI000D1262D2 +-tELKKIIESIIAGKKADVGVSIMETPKKEVI-QINGSKFYPMLSTVKFHIALSVLHQIE +KGELSLQQKIYIKKEELLEWSPFQKEHPEGNLTLEEAMKWMVSYSDNNLTDILLRLIGGP +QTVQKFINS---KEFVIKNDEEGMHKDWDSQFINVTTPNEAIKLLEQFYNGKLLNKEHTK +WLYTAMLNNASGAKRLKAHLPKNFKIAHRTGTSFTGAVNDFGIVELPEKKRIYIAVFVHN +SYESFDNTEAIIADIAKATYDYy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Microscillaceae bacterium TaxID=2053581 RepID=A0A349E4P4_9BACT +-qALKEKINQVLKGKSATVGVAIQGANPKERL-SINGDKHLPMQSVYKYHLALTVLHQVD +QGKFSLDQKITLDKKMVEAWSPLRKKYPNGTISLAEVIKYTVAWSDNLGCDLLFKLIGGP +KIADAYMHKIGIKDIAIVYPEIVMQAKWHIQYENWTTPKAANQALQLFFENNLLTQKSHD +FLLNVLKGTKTGKKRIRGLLPKETVVAHKTGYSGTGALNNIGIVFLPDNTYFYISVFVSD +SSESNATNQQIIAKIAKLAWDYf +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. GDMCC 1.1288 TaxID=2282649 RepID=A0A3E1YG65_9BACT +--SLKSDVQALIAKSKSRVGVSVIGPEGNDIL-DLKSGERFPMLSVFKFHIGLYVLHLVD +KKELTLNQLVHIDSSDLMKWSPLAKLYPNGNLPLEKILSYTISQSDNNGCDILLKLVGGP +DSVQNYMKKLGVKDISIVATERDMHASWEAQYKNWTSPWAATHLLKAMDENRILSRSSTS +VMLKFLMETAI-TDRLNGLLPKGTKVAHKTGTSGTPATNDIGIIELPNGQHYYIAVFVND +SWESDKKNARLIAEISKAVWDY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL45_ECOLX +-----------------------------------------------KVMAAAAVLKKSE +SXPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPXSWVVGDKTGSGGYG------------------------ +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=T0IMS5_9SPHN +--KLLGEFERFATLSDGTVGIAVRDLQTGETQ-AINGDTLFPMASAYKVAVAGRIFALID +AGDVRLDDQLTLDPALASEGIAWMFSRPGASLSVQRLLELMLQKSDNNATDVLVARAGGP +AAITQFVRGLGVDGLRVDSDTAHLLYAFAAEIEDTSTPRAMLDLLTAYESGKALSADSTQ +RLFTIMAHCETGKARIVGMLPPGTAVAHKTGSLN-GTGNDVGIVRLPDGRRFAVVAFVMK +DSKGHKSRDRIIAEAARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter atlanticus TaxID=1648404 RepID=A0A0H4VW64_9SPHN +-nQLELRIAQLAEGSNGRIGVAAVDLATGQTI-SVLGDQRFPLASTSKIAIAATFLEGVD +QGRWSLTSEFPLMVPVGSRSSHAAPVRRGEHLSALRLIDLMLTRSSNTATDALLAAIGGP +QAVNEWARRSGLQNFSIDRDIATLVRVVHIDPRDSASPAAMVQLLAGIYQGRWLSSRSRE +VIIDAMERCRTGTRRIPALMPSNVTVAHKTGSLNN-TSSDIGILTAPDGRAIAVAIYVTG +QG-NRLNRERRIASIARGVYDGy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A6A1XN92_BACOV +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDTHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRIYSIAVFVKD +SEENSQANSKIIADISRIVYEY- +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter xinjiangensis TaxID=762261 RepID=UPI000F7E3CD0 +---LEQRIAELADGARGRIGVAAIDLVTGEEV-SILGDQRFPMASTSKIAIAATFLEGVD +QGRWKLSDRFPLMVPVASRSSEKAPVRPGTVLSASQLLELMLTRSSNTATDGLLAVVGGP +SAVNDWATRAGIPNFQLTRDIATLVRAVQVDVRDSTTPRAMTKMLVGLYQGKWLSRSSRN +LLIGIMEKCRTGVRRIPALLPDGVTVAHKTGSLNN-TSSDVGIVTGADGHAIAVSIYVTG +QG-SRPGRESKIAHIARALYEGy +>[subseq from] Beta-lactamase n=1 Tax=gamma proteobacterium NOR5-3 TaxID=566466 RepID=B8KHB2_9GAMM +----SNLLKTLTKDLVGVLGVAAQRPGYQGRI-LVNADEPFPMASTYKIPIAITLLRRID +QGELRLDQLVPVPDEAVVFSQIIASAFPHSGISVANLIEVMITYSDNTATDICLELAGGP +EAVTKTMRSLGIQGLHVDRSTAELLKDFEADGKDKSTPRAMLSLLLALKAGETMSQAGTD +FLLGAMSRTVTKPDRLGRLLPKGTQVLHKTGTVG-GVVNDVGYIRLPGGDEFAIVVFTKS +STTDPADRERAIGEVARSLYDYf +>[subseq from] serine hydrolase n=1 Tax=Croceicoccus sp. S2-4-2 TaxID=2571150 RepID=UPI001181FF0B +---LRQNLFAVARPDKGRIGVAAMDLSTGQTV-SILGDQAFPMASTSKIAIAATFLAGVD +QGRYRLDSKYPLMIPVASRSTSVAPVKPGMELTARSLIELMITRSDNTATDAMLKAVGGP +AEVTKWMRSKGFERFRIDRDIATLVRATGADQRDSTPPAEMVRLIAGLYKGEWLSGESTD +VVIGAMTRTVTGRRRMKAGLPSGIDFGHKTGTLNN-TASDVGFVEMPDGRVVVMAIYVTG +QG-GRPQRDARIAEITRTLYNGf +>[subseq from] Class A beta-lactamase n=1 Tax=Rathayibacter sp. Leaf296 TaxID=1736327 RepID=A0A0Q5B5B2_9MICO +------------------MGLVAVDSEDERTV-EHRADERFRFASSIKALAAGALLARTE +--PSDLERVVTW--SDVVDHSPVTGPATATGLPLGEVAEAAVRLSDNTAHNVVLQELGGP +AGLQEALRALGDDVTRVDRVEPELNRVSPE-GLDTGTARSLAADLRTLLLGDPLDSADRA +QLRDWMSGNATGDALVRASAPDGWSVLDKSGGAG-GLRNDLAVVERPGAAPIVIAVLTER +TDPTLPYDDALVARAASVALE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=M9UYD2_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAGLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora viridifaciens TaxID=1881 RepID=A0A1C4YTZ3_MICVI +-------LDRLEAEFDARLGVYAVDTGSGRTV-AHRADERFAYCSTFKALAAAAVLDATS +--TAELDQIVRYSRADLLTYSSVTERHVDTGMTLRAVAEAAVRHSDNTAANLLLARLGGP +AGFQRVLRGLGDQVTEPARTEPELNAAVPGDVRDTSTPRALVGDLRAYAVDDALSAEDRA +VLVDWLKRNTTGGRSSGRVLPAGW------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Legionella donaldsonii TaxID=45060 RepID=A0A378JD83_9GAMM +--QLVKKIYDIEKRSNAVIGITAIHIEKNKVI-GHNGNKRFFMASTIKLPIAIAFLHLVD +QKKDSLNRVVNLGLNNVVPGSGTLHYLCERKMSLQQILKYMMANSDNSASDTLLQTVNGP +AYVTKRMHALGFKNIVINRSIIEMMMRFEKDPRDTTTPAEMAKLLVKIYKNEALSESSTK +VLMDIMEKCRTGRSRIRGLLPPYVKVAHKTGTWAFRFVSDVGIITLPNNGHIAIAVYVKS +RAVSNYTRSRAIALASRAIYDHf +>[subseq from] class A beta-lactamase n=1 Tax=Renibacterium salmoninarum TaxID=1646 RepID=UPI0009B5CEB8 +---LDGKLTKLEQDAEITLAVCAS-VQGGQRL-EYRATEPLAMCSTFKAILVGVLLSKHA +RDDSYWATQVMIDPAKVLSYAPITQPFAGRPMPIADLCDATLRYSDNTAANLLLEQLGGP +PALTFFAADLGFKNTRLDRTEPDLNESKAGDARDTSTAADLAGIYSALLLGDALGALGQS +MLRGWMLRNTTSAQKMGAGIPKEAELADKTGSGSYGTLNDVGVIFRKAKPPVTLAILSRA +VSTDPNE---------------- +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=Q2GBP5_NOVAD +-qAIQQQVAAIAAEGRGRIGVAAMDLDGGGQI-FVNGDMPFPMASTAKVAVAATFLEQVE +KGNFRLDQQFPMMVRVAETGRVSAEAPLRAGMTAQSLMELMITRSHNEATDGLIHAVGGY +ENVNRWLTRNGITGQRLDHTMATLVRAKVIDTRTSSTPRAMIALLAAIDRGGVLSPESRA +VLLDTMTRTSTGKTRIRAGLPVGTLVAHKTGTLS-GVTDDVGIIRLPDGRHLAVAFFVTG +PEG-HAAHAALIARMTRVIYNGy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. HF-5092 TaxID=2594500 RepID=A0A553EKY8_9BACE +-nKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVQECVIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKAYKD +FIYQTMVECQTGKDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPDGRIYSIAVFVKD +SEENSQANSQIIADISRIVYKY- +>[subseq from] Beta-lactamase n=2 Tax=root TaxID=1 RepID=A0A4Q5EDB0_BACUN +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides congonensis TaxID=1871006 RepID=UPI000934FAA8 +--SLETQLKKAIKDKKAEIGIAVI-IDGKDTV-TVNNDTHYPLMSVFKFHQALALADYMG +KHNQSLDTLLTIEKSDLKSYSPLRDKYPEGGMSIAELLKYTLQQSDNNACDILFHYQGGP +DSANKYIRSLGIQDCEITHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRREPLFAKEYRD +FIYQTMVECQTGQDRLVALLDKGVIVGHKTGTGDRNGCNDIGFVVLPDGHTYSIAVFVKD +SEESSPENSKIIADVSRIVYEY- +>[subseq from] class A beta-lactamase n=1 Tax=Dyella sp. C11 TaxID=2126991 RepID=UPI000D652A59 +--SLQQALDALAQRAPATLGVAVLDLSTGASA-HVNAGRDFPMMSMFKAPVAAAVLSRID +DGSMSLKQSVTITRDQVQGGSPSVGAHFRGEFTVEQLLKAAVTESDNTAVNALIRAVGGA +SVVTGYLHAHGINGMRVDMDEAGVAQAFLADPRNRSTPEAAIDFLHKLVKQELLSPASTQ +RLLAMMAAQTI-PNRLRAGLPANVRFADKTGTSARGAFNDIGIITWPNGHTVLVAAFLMD +SPMTDKARDALFADLARNVVS-- +>[subseq from] Beta-lactamase n=4 Tax=Francisella tularensis TaxID=263 RepID=A0A0E2ZP54_FRATU +--QLDDSFKNLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM +HNQGFLDKKIPINQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDSPASNILVRELGGL +QNLNKFIKKLGDNDTIITADEPEINYTQPHSNINKTTPKAITKDIYKLAFGNILDKKHKD +IFIKYLQDNNTGANRIAFSMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN +PNKNAPSNEEIIQQAAKLIAN-- +>[subseq from] Beta-lactamase 1 n=1 Tax=Listeria grandensis FSL F6-0971 TaxID=1265819 RepID=W7BRK6_9LIST +------------------------------------------------------------ +------NKRIHFKKEDLIDHSPITEKHTEDGMTLKEIINAAMTYSDNTAANLMLHELGGP +KAYQKELVKIGDTVTQSDRYEPELNSAVPGDKRDTTTPEAMAKNLAFLVKKGNMPTDNFN +YFKQTLIDNTTGDKLIRAGVPEGYIVGDKTGSGSYGTRNDIAVIYPKDKKPLVWVIYSKK +DTEDAEYDDQLIADAAKVLSKYf +>[subseq from] Beta-lactamase n=2 Tax=Legionella worsleiensis TaxID=45076 RepID=A0A0W1AJI0_9GAMM +--EIAKKIAAIEKKSNAIIGISAIHIENNKVI-SHNSTQRFFMASTIKLPIAMAFLHRVD +QKKDSLNRIIKLGLSNAVPGSGSLHHACERKMSMQQILKYMLTDSDNSASDTILHTVNGP +EYVTKWMYELGFKNILINRSILEMFMRFEKDKRDTTTPDEMAKLLVKLYKKEALSASSSK +ILINIMEQCRTGRSRIKGLLPSHVKVAHKTGTWAPGFASDVGIITLPNKGHIAIAVYVKS +QAASDYSRSRAIALASRAIYDHf +>[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma fluviale TaxID=1597977 RepID=A0A286GR14_9BACT +--RLEKELLRLSNMSEGTVGICAVHIESGKTI-TQNGKDHFPMASSYKVAIATQLLSRVD +SGSLALNQLIPIVKTDFHPGSGMLPNSPATDLSVRSLLELMLLISDNSATDICLRLAGGP +AAVNACMKRIGVEGLRVDRPTAWLIAAFENDIRDTSTPEAMTLLLTKLYTQPVLKPASQA +LMLDIMKRCETGLARLKGALPPNTEVLHKTGTIGL-TASDVGIITLPDNGHVAISVFVKA +SKKEGAVRERTIAEVTRTIYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000379CF86 +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVCFLHRLATGQLLSASSTA +HLLEVMNRTTTFPDRLRSGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAXAITAAY--- +>[subseq from] Uncharacterized protein n=1 Tax=Flavobacteriaceae bacterium JJC TaxID=512012 RepID=A0A246AJW8_9FLAO +-qNLKKEILKITKDKNATVAVSVNGIDFPYEFnNENADKKLPMLSVFKFHIAAAVLNEVD +HGKLKLDQKIPLKKSDLLEHSPLRDKYPNANLTVDEIIKYTVAQSDNNGCDILLRLIGGT +QTVQKFMDSKGIKNFQIKYNEEWMHKGKEYLYPNYTTVKSLSLLYKSFFEKKILSEKSTA +YLMNIMLGTTTGANKLKEQLPAGTAIAHKTGSSGKDAENDSGIITLPDGKHYAITVFVID +STESEAVNTKMISDISKKVWDHf +>[subseq from] Class A beta-lactamase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8NU28_9BACT +---LRAEIEKLIPRAGGGVGVAIKHIESGTEL-MINADEKYPMASAFKLPILVELFYQRA +AGKLSLDDRVEIAAGDLHVGSGSMSQLFDAPLSIRNLINLMMRISDNSAADILLNKA-GA +ANVSSRMRALGLETIRVDRTTQEMILEFSKVEKDVSSPRDMNILLEKIFRGEIVDRSTSD +EIIQILKQCQTGLTRIRGLLPQDTVVAHKTGTIG-GTTNDTGIVFLPRGDHLVITVFTKD +AKAPPAERERVIAEISRYAYDYf +>[subseq from] Beta-lactamase n=2 Tax=Novosphingobium sp. Leaf2 TaxID=1735670 RepID=A0A0Q4CBB3_9SPHN +-----QQLAAVANASQGRIGVAAMDLATGRMV-DVLGDQRFPMASTSKVAIAATFLDGVD +KGKWTLSSEFPMMVPVPSASTAVAPVRAGEYMSAQRLIELMLTRSNNYATDALLRVVGGP +RAVNAWVERAGIEDWHIDRDIATLVRARVVDKRDSATPKAVVNLLAGIYQGKWLSPSSRA +VLLNTMGRCVTGKRRISAGVPAGVQVAHKTGSLNN-TSSDVGIIQTPDGRAFAVAIYVTG +QG-GRPGREARIASIARTIYNGy +>[subseq from] Uncharacterized protein n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1IUJ0_9ZZZZ +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRN------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Legionella feeleii TaxID=453 RepID=A0A0W0TM57_9GAMM +--QLVKKIYDIEKRSNAVIGITAIHIEKNKVI-GHNGNKRFFMASTIKLPIALAFLHLVD +QKKDSLNRVVNLGLNNVVPGSGTLHYLCERKMSLQQILKYMMANSDNSASDTLLQTVNGP +AYVTKRMHALGFKNIVINRSIIEMMMRFEKDPRDTTTPAEMAKLLVKIYKNEALSESSTK +VLMDIMEKCRTGRSRIRGLLPPYVKVAHKTGTWAFRFVSDVGIITLPNNGHIAIAVYVKS +RAVSNYTRSRAIALASRAIYDHf +>[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia TaxID=28110 RepID=A0A0B6CRW7_9GAMM +--ALDDSFKNLEDKYHGKLGIYTVNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM +QHEGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL +EKLNKLVTKLGDKDTIIKNDEPKINHTKPDSDINKTTPKAITQDINNLAFGNILDIKHRE +IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQNKPPFALSILYTN +PSVKAPSNEKIIQQASKLSA--- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium contaminans TaxID=1423959 RepID=A0A1M6Z8T5_9FLAO +--EFKKNIEAILANKKADVGVSILTSGTKKEVtQINGNKPFPMLSTFKFPIALAVLHKVE +KGELSLQQKVYIKKEELLEYSPFREKYPEGNISLEDCIQWIVVYSDNNLTDVLLRMIGGP +DYVQNFINS---KDTVIKNDEKDMHKDWDSQFINTITPNEAIRLLEQFYNGKILNKEHTK +WLYTAMLNNVAGVKRLKGKLPKEVKVAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHD +TYETFENSEAIIADIAKTAYDYy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia multivorans CF2 TaxID=985078 RepID=J5BJ40_9BURK +--RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS +LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMDVLGGP +QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA +QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRG----------------------------- +----------------------- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=A0A414GNX3_9BACE +-sKLETKLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDTHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRIYSIAVFVKD +SEENSQANSKIIADISRIVYEY- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A6C1QMN7_9BACT +-hDLRESINQIISSKNALTGVAIAGHDGKDTL-SLNGNLQFPMQSVFKFHIALAMMAEID +KGNFSPEQKVRIKKDDLLPYSPLRDKHPEGALTIAELSKYAVALSDNVASDALLRLLGGP +LRVECFFADNGFADISIKINEEEMQSNWDLQFKNWTTPMASNQILRAFFEDHLLSQASHE +FIWRIMGETITGRNRIRGKLPHSTDVAHKTGWSGTAAVNNIGIVFLPDDSHFYISVFVTD +SKEDFQTNEQIIADIAKAAWDYf +>[subseq from] Beta-lactamase n=2 Tax=Pseudomonas acidophila TaxID=1912599 RepID=A0A1I9RH04_9PSED +hdALQKTLDRFASAAPGTLGVAVLDMQGSTGW-QVNGNQAFPMMSVFKAPLGAAVLDRVD +KGELKLNQRVTITRDELRPRSAIRGAFQGDRFPLADLLHAAISESDNTGADALLRLIGGP +QAVTAYLRAHGIHGMTVDMGEGQVADAYLSDPRNRTTPAAAADFLRKLSTGALLSPTSTQ +YLMTLLNEQVT-PRRLRVGLPAGVTFADKCGTSLTAAFNDIGIITWPDGHRVIVAAFLMA +SHASREERDRLFADLARAIVA-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SPR3_9BACT +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIKKLGINDFNLSETEDSMHRNPQKAYSNWSTPSEMVRLLKMADEKDLFAPVYRD +FFWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] Beta-lactamase n=3 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SF18_9BACT +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIKKLGINDFNLSETEDSMHRNPQKAYSNWSTPSEMVRLLKMADEKDLFAPVYRD +FFWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] Beta-lactamase n=4 Tax=Francisella tularensis TaxID=263 RepID=A0A0B3VPP7_FRATU +--QLDDSFKNLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM +HNQGFLDKKIPINQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDSPASNILVRELGGL +QNLNKFIKKLGDNDTIITADEPEINYTQPHSNINKITPKAITKDIYKLAFGNILDKKHKD +IFIKYLQDNNTGANRIAFGMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN +PNKNAPSNEEIIQQAAKLIAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Cy-637 TaxID=2608327 RepID=UPI00141E1847 +hdALQATLERFAQAAPGTLGVVVLDLERPARW-QVNGTLPFPMMSVFKAPLGATVLDLAE +QGRLPLGQRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP +AVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR +RLLGLLRDQTQ-PRRLRAGLPPGVTFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA +SRASRAERERLFADLARAVAS-- +>[subseq from] Serine hydrolase n=1 Tax=Altererythrobacter sp. Ery1 TaxID=2306995 RepID=A0A418NL45_9SPHN +---FERQIVRLADGANGRIGVAVLDLATGQEF-SVLGDQRFPMASTSKIAIAATYMEGVE +QGRWSLSSEFPLLIPVRSEFSTVKAPVRRGKLPASQLIELMITRSSNSATDALLAAVGGP +GAVNDWMRRAGIEEFQLTRDIATLVRARAVDLRDSATPRAMTELLAGLYQGRWLSKSSRQ +VILGAMERCITGKRRIPALLPAGASVAHKTGSLNN-TSSDIGIVHTPDGKAFAVAIYVTG +QGAR-LAREHKIAQIARAVYSGy +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter endophyticus TaxID=1808508 RepID=UPI00135D97E5 +--DFERTVANLAAGDKGRIGVAALDLSSGKEI-AILGDQRFPMASTSKIAIAATFLEGVD +QGRWSLTSEYPLMVPQRSQSSATAPVHKGSYLPASQLLNLMLTRSSNSATDALLAVVGGP +DAVNAWAKRAGIGEFELTRDIATLVRAAHIDHRDSATPRAMVQLLTGLYQGRWLSSESRN +LLINTMEECRTGKRRIVADMPSSVTVAHKTGSLHN-TSSDIGLLTTPDGRTIAVAIYVTG +QG-SRLNRERRIASIARAVYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Sphingosinicella sp. CPCC 101087 TaxID=2497754 RepID=UPI00101CA34C +---LDTRIRQLAQGFDGDVGIAVRDVESGWTT-SWNGTRHFPQQSVSKFWVALTAFQRVD +AGELDLSQRVTLRREDLTLHQPIASQIGSNGTTLGDLLFRALTQSDNTANDAVLRRAGGP +EAVRAMLARKGIQGVRFGPGERLMQSSYVEDPIDGATPEGLVEGLARLQRGELLSRASTE +RMLSIMSQTRTGRQRLTGGLAPGWRIAHKTGTGQQTGYNDIGILTSPEGRHYAVAVMIGR +TSVPIPRRMELMQDVTRAVI--- +>[subseq from] Beta-lactamase n=1 Tax=Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235) TaxID=288705 RepID=A9WLK3_RENSM +-----GKLTKLEQDAEITLAVCAS-VQGGQRL-EYRATEPLAMCSTFKAILVGVLLSKHA +RDDSYWATQVMIDPAKVLSYAPITQPFAGRPMPIADLCDATLRYSDNTAANLLLEQLGGP +PALTFFAADLGFKNTRLDRTEPDLNESKAGDARDTSTAADLAGIYSALLLGDALGALGQS +MLRGWMLRNTTSAQKMGAGIPKEAELADKTGSGSYGTLNDVGVIFRKAKPPVTLAILSRA +VSTDPNE---------------- +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. BPTF-M16 TaxID=2169535 RepID=A0A411ZEV6_9SPHN +--SFERRIAQLADGSRGRIGVAAIDLNTGDEV-AVLGDQLFPMASTSKIAVAAAYLELVE +QGKYSLTSEFPLLIPVRSASSRAAPVREG-NMSAEDLIEIMIARSSNPATDALLRVVGGP +EAVNDWMRRQGIDEFSIDRDIATLVRSMHIDTRDAATPKAMIELLQGLYRGDFLTAESRQ +VILDAMAKTRTGKRRIRAGMPDYVGVMHKTGSLNN-TSSDIGIIEGPNGHAIAVAIYVTG +QGA-RSAREARIANIARALYDGf +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter dongtanensis TaxID=692370 RepID=A0A1B2A9D4_9SPHN +---LSKTVAQIADGSAGRIGVYAVDLATGREV-SVLGDQRFPMASTSKIAIAATFLEGVE +KGRWSLTSEFPLMVPVASPSSSKAPVRPGQYMKAIDLIEIMITRSSNPATDALLAVVGGP +AAVNNWASRNGISDFNITRDIATLVRAQRIDVRDSATPQAMVQLLAGLYQGKFLKESSRN +VILGAMERCRTGTRRIPGMLPDGARVAHKTGTLSN-TASDIGIIHTPDGRAIAVAIYVTG +QG-SKPARDAKIASIARALYDGy +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A139LHC4_BACOV +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFCKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRTYSIAVFVKD +SEENSQANSKTIADISRIVYEY- +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SN54_9BACT +-dDLKNNILTIIDSKKATVGVALI-VDGKDTL-TINNEIHYPMQSVYKFHLALAVLNYMN +LNKMPFDIPVYIKKSDLLPHSPLRDDHPEGEMPVTEVLQYTVSKSDNNGCDILFRLLGGP +KEVDRYIKSLGISEVNIAATEEEMHSGWEVQFWNWTTPLATVELLEKFRTGDVLPMPYHD +FLWKTMVETSTGANKIKALLPEGTIVAHKTGSSFRNAENDIAVVQLPDGRYYSLAIFVSD +SKESDETNCRIIAEISKAIYDH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Kluyvera intermedia TaxID=61648 RepID=B2CD66_KLUIN +-------------------------------------------------LLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWYFAD-------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=bacterium (candidate division B38) B3_B38 TaxID=2012999 RepID=A0A532UBV2_9BACT +---LQSQIEKVIHRVDGVVGVAIKHLESGEEV-KINGDTLFPMASTFKVPIMVEVFHQIN +EGKFGLDDEAEMTETDLHLGSGMLSSLQAPGLSIRNFITLMMIISDNSAADFLLQKV-GV +DNVNHRMEALGLTDIHIDRTCHQLIMLFNREAKDVCSPADMNSLLEKIFKAEMLDRETCD +LMLQIMLRCQTGEKRLRGILPRGTRVAHKTGTIVT-TVNDCGIIYLPNRGHIVITVFSKE +VEDETADMEKVIAEVARFAFDYf +>[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=A0A3S3QYR9_RHIML +--RLRLELETLADAHPGRVGICVQD-QPKSPV-CVNGAQRFSLQSVMKLVVAAAVMQAVD +EQRIRLDDQITIRREDLSVIQPIADIVARHGTSVRDLVRRAVVASDSAATDVLIARLGGT +KAIQVFLEMAGLTGVRIDRTERELQTAYIKDPRDTATPRGMAAFLYSLASGSLLTAGSTE +FLLTVMSQTTTFPDRLRAGIPPEWGIGHKTGTSQNGVTNDVGILTAPDGRRIAVAAFVAE +SRAGQAERAAVIAAAARAITAAy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0R5RPM3_9BACT +-kELEQQIGQVLKDKKATVGVAVLANDTIVA--LHNNQIHFPLFSVFKFHVALAVLDKMD +KGHVSLDSIMEIKAAQMLPYSPLRQKFPDRDISLGELLKYSISLSDNNACDVLIDYVGGI +DKVNSYIKSLGLKDFNLAANEDLMNRDVATQYQNWSTPEAVVRLLNIADKQTLFAAGYKD +FLWQILKETSTGTDKLKGELPPDVIVGHKTGSSNKTADNDAGFIILPDGRKYYITVLVME +SQETDRENAAIIARISKIVYD-- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter gaetbuli TaxID=266952 RepID=UPI0013619911 +-nAFEQRLAELADGSNGRIGVAAIDLTSGQMV-TVLGDQRFPMASTSKIAVAATFLEGVE +KGKWSLTSEFPLLLPRKSASSKVAPVYEGEYMKAIDLIEIMITRSSNPATDALLRVVGGP +DAVNDWVRRQGIRDFSIDRDIATLVRAQHIDKRDSATPKAMLDLLSGLYQGKFLKPESRR +VLLGAMSRTRTGKRRIPALMPESVRVSHKTGSLNN-TSSDVGILETPDGRAVAVAIYVTG +QG-SRLNREAKIAQIARAIHDGy +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. MBES04 TaxID=1206458 RepID=A0A0S6WVK6_9SPHN +---FERQLAAAAEASNGRIGVAAVDLRTGRTL-DVLGDQRFPMASTSKIAIAATFLEGVD +KGKWTLTSEFPMLIPVSSKSSAVAPVREGQYLTAAKLLELMLTRSNNYATDGLLRVVGGP +DAVNAWVRRAGIEDWHLDRDIATLVRANVIDKRDSATPMAMVTLLRGLYEGQWLSKRSRD +TLIAIMGRCVTGRRRIPAGIPDGAMIHHKTGSLHN-TSSDVGIVETPNGDVFAVAIYVTG +QG-SRPNREARIASIARTVYNGy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides stercorirosoris TaxID=871324 RepID=UPI001114E074 +-kELEQQIGQVLKDKKATVGVAVLANDTIIA--LHNNQIHFPLFSVFKFHVALAVLDKMD +KGHVSLDSIMEIKAAQMLPYSPLRQKFPDRNISLGELLKYSISLSDNNACDVLIDYVGGI +DKVNSYIKSLGLKDFNLAANEDLMHQDVATQYQNWSTPEAVVRLLNIADKQTLFAAGYKD +FLWQILKETSTGTDKLKGQLPPDVIVGHKTGSSDKTADNDAGFIILPDGRKYYITVLVME +SQETDRENAAIIARISKIVYD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0F7LFU0_ECOLX +---------------------------------------------------AAAVLKESE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTN--------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia TaxID=28110 RepID=A0A0E1N7H4_9GAMM +--TIDDSFNNLEDKYHGKLGIYTVNTDDKINI-SYNENYHFPICSVFKFLLVGAVLEYDM +QDKGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL +EKLNKLVAKLGDKDTIIKNDEPKINHTKPDSSINKTTPKAITQDIYNLAFGNILDKKHRE +IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQNKPPFALSILYTN +PSVKAPSNEKIIQQASKLTAN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercorirosoris TaxID=871324 RepID=A0A1M6H4V1_9BACE +-kELEQQIGQVLKDKKATVGVAVLANDTIIA--LHNNQIHFPLFSVFKFHVALAVLDKMD +KGHVSLDSIMEIKAAQMLPYSPLRQKFPDRNISLGELLKYSISLSDNNACDVLIDYVGGI +DKVNSYIKSLGLKDFNLAANEDLMHQDVATQYQNWSTPEAVVRLLNIADKQTLFAAGYKD +FLWQILKETSTGTDKLKGQLPPDVIVGHKTGSSDKTADNDAGFIILPDGRKYYITVLVME +SQETDRENAAIIARISKIVYD-- +>[subseq from] FTU family class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI0007060969 +--QLDDSFKNLENKYDGKIGIYTLNTNDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM +HNQGFLDKKIPINQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDSPASNILVRELGGL +QNLNKFIKKLGDNDTIITADEPEINYTQPHSNINKITPKAITKDIYKLAFGNILDKKHKD +IFIKYLQDNNTGANRIAFGMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN +PNKNAPSNEEIIQQAAKLIAN-- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. AAP93 TaxID=1523427 RepID=A0A0N0KB86_9SPHN +--AIEQQVSAIVAQGRGRIGVAAVDLDGGGQI-MINGDMPFPMASTAKIAVAATYLSGVE +QGRLRLDQQFPMMVPVAEARGTVAAVRPGMVMSAQSLMELSITRSDNHATDGLIAAVGGI +GAVNTWLNRIGVTGQHLDHTMATLVRVTTIDTRTSSTPRAMVQLLAAIDRGGALSPESRA +VLLDTMTRTSTGKNRIRSGLPEGVVFAHKTGTLA-GVTDDVGIVRLPDGRHLAIAIFVTG +PEG-HTAHAGLIAQIARVLYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonadaceae bacterium KCTC 52780 TaxID=2172047 RepID=UPI000E0D3003 +---LDARIRQLGQSFDGHVGIAVRDVATGRTS-SWNGDRYFPQQSVSKFWVAIAALQRVD +AGQLDLSQRVTLTRNDLTLHQPIATQIGTGSTTIGELMFRAITQSDNTCNDFVLRRAGGP +EAVREMLTRNQLNGVRFGPGERLMQSAYVEDPIDGATPEGIVEGLARLQRGELLSRASTE +RLLSIMSQTRTGRQRLTGGLAPGWRIAHKTGTGQQAGYNDIGIITAPDGRHYAVAVMMGR +TSVPIVQRMEFMQDVTRAVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Francisella novicida TaxID=264 RepID=A0A2L1CI97_FRANO +--QLDDSFKNLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM +HNQGFLDKKIPINQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDSPASNILVRELGGL +QNLNKFIKKLGDNDTIITADEPEVNYTQPHSNINKTTPKTITKDIYKLAFGDILDKKHKD +IFTKYLQDNNTGANRIAFGMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN +PNKNTPSNEEIIQQAAKLIAN-- +>[subseq from] serine hydrolase n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000C801966 +--SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD +AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMITVSDNTATNMLIARMGGI +EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGTLMAMVSQGNLLNMASRD +RILDIMRNTVR-NHLLPTGLEQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR +PNND-PRAEKLIASISKATYQQf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacterium multivorum TaxID=28454 RepID=UPI00129C626C +-nNLRKELHQIISTKNATVGISMKGIEDKDTL-SINGHLNAPLMSVFKFHIALATLDLVD +KGKLSLSQKFFIKKEDLHAWSPIRDEFPNGNLTLDQLLRYTVSHSDNNGCDILLDLIGGP +ETVQKFIHKQGIKDFTIKVNEQEMR-IWENLYINTTTPLASTELLEKFYAGQVLKKNTTN +YLYQLMVECSRGLTWMKAGLPEGTELAHRTGISDRAAMNDVGIFKLPNGNHIVLSVYLKD +ITEEREVTEKIIADITKSIWNYy +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. BW1 TaxID=2592621 RepID=A0A5D0WZG0_9SPHN +---FERQLAAAAEASNGRIGVAAVDLRTGRTL-DILGDQRFPMASTSKIAIAATFLEGVD +KGKWTLTSEFPMLIPVSSKSSAVAPVREGQYLTAAKLLELMLTRSNNYATDGLLRVVGGP +DAVNAWVRRAGIEDWHLDRDIATLVRANVIDKRDSATPMAMVTLLRGLYEGQWLSKRSRD +TLIAIMGRCVTGRRRIPAGIPDGAMIHHKTGSLHN-TSSDVGIVETPNGDVFAVAIYVTG +QG-SRPNREARIASIARTVYNGy +>[subseq from] Beta-lactamase n=1 Tax=Tolypothrix campylonemoides VB511288 TaxID=1245935 RepID=A0A0C2Q8I6_9CYAN +--RLQRKLEAVAKGSDGRVGICAEEMKSGAIA-CVNGDQRFSLQSVMKLVVGAAAMDAID +RGQMRLEDVITVRKKDLSLVQPIADLVAERGTTVADLISRAITESDSAATDLLFARVGGA +EGIQTFLKTKKISGLRVDRDEKHLQTAYLKDERDTATPRGMVTFLSALASGKLLSAKSTA +YLLKVMQRTVTFPDRLKAGVPKGWTLGHKTGTSLTAVTNDVGILTAPDGGTISVAVFVAE +SRRSSKERAKVIAATAKTITSSy +>[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI000C999CC6 +-----ATVQKLAHSLEARVGMAAVMLDTGETV-SIGDEAAYPMQSVFKFILALSVLKQVD +EGKLDLEQIIHIRPEQLLKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT +GTVQKDLKEWGISGINVRFTENEMLRNHDLQYVNSSRPSAMNALLRAFDEGKILNKGTQR +FLWDIMAGCSTGATRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD +SKDSLPACEKVIASMARWLCTEw +>[subseq from] Uncharacterized protein n=2 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=I9JMQ7_9BACE +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVRECAIIGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRTYSIAVFVKD +SEENSQVNNKIIADISRIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=Dyella jiangningensis TaxID=1379159 RepID=A0A328PCE8_9GAMM +---LQQALDVAVRARPGTLGVAVLDMGSGARA-GVHTDEAFPMMSVFKAPVAAAVLAQVE +EGSLSLEQEVTLARTDLRDGSAVPQLAAGKTFTIGRLLRGAVSESDNTAVDALLRVLGGP +QKVTAFLQAHGLKGMRVDLGEGGVNEAFLADPRNRSTPAAAVEFLRKLQGGELLSPASTQ +RLQHLMAEQTL-PNRLRAGVPQGVRFAGKSGTSGTQAYNDIGILTWPDGQAVIVAAFLSD +SAMPAPQRDALFADLARAVAR-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SPU7_9BACT +-sELKNRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISLSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Beta-lactamase n=3 Tax=Burkholderia gladioli TaxID=28095 RepID=A0A095H6B9_BURGA +hdALQATLERFAQAAPGTLGVVVLDLERPARW-QVNGTLPFPMMSVFKAPLGATVLDLAE +QGRLPLGQRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP +AVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR +RLLGLLRDQTQ-PRRLRAGLPPGVTFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA +SRASRAERERLFADLARAVAS-- +>[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. MBES04 TaxID=1206458 RepID=UPI000A01D41C +---FERQLAAAAEASNGRIGVAAVDLRTGRTL-DVLGDQRFPMASTSKIAIAATFLEGVD +KGKWTLTSEFPMLIPVSSKSSAVAPVREGQYLTAAKLLELMLTRSNNYATDGLLRVVGGP +DAVNAWVRRAGIEDWHLDRDIATLVRANVIDKRDSATPMAMVTLLRGLYEGQWLSKRSRD +TLIAIMGRCVTGRRRIPAGIPDGAMIHHKTGSLHN-TSSDVGIVETPNGDVFAVAIYVTG +QG-SRPNREARIASIARTVYNGy +>[subseq from] class A beta-lactamase n=2 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000626EE9A +hdALQATLERFAQAAPGTLGVVVLDLERPARW-QVNGTLPFPMMSVFKAPLGATVLDLAE +QGRLPLGQRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP +AVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR +RLLGLLRDQTQ-PRRLRAGLPPGVTFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA +SRASRAERERLFADLARAVAS-- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter marinus TaxID=874156 RepID=A0A0H0XTD6_9SPHN +-nALEARIAQLANGSEGRIGVAAVDLATGQTI-SVLGDQRFPMASTSKIAIAATYLEGVE +QGRWSLTSEFPLLWAVRSRFSTNAAPVRRGEMTALQLIDIMITRSSNPATDALLAAVGGP +AAVNDWARRAGLRDFSLDRDIATLVRASHIDVRDSASPETMVQLLAGIYQGRWLNSASRE +VIIDAMERCRTGTRRIPALMPDNVTVAHKTGSLNN-TSSDIGILTGPDGRSIAVAIYVTG +QG-SRLNRERRIASIARGIYDGy +>[subseq from] class A beta-lactamase n=2 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000F805CBD +hdALQATLERFAQAAPGTLGVVVLDLERPARW-QVNGTLPFPMMSVFKAPLGATVLDLAE +QGRLPLGQRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP +AVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR +RLLGLLRDQTQ-PRRLRAGLPPGVTFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA +SRASRAERERLFADLARAVAS-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides uniformis TaxID=820 RepID=A0A3E4R3J8_BACUN +-sELKNRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQNISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WRM6_9BACT +--DLTALIEKTAGPAKGRVGVFAVVLETGDSV-SLDPDGRYPMQSVYKFPISMVVLRQVE +EGKLKLDQKVRVEKEEYVRRSPLRDKNPNGAVTVQELIRLSIVESDGSASDALMRLAGGA +AAIQEYLTGINVGEVIVANPEKEIGQDWETQYRNWATPEGAASLLRALYEKRGISDQHQK +LLLKFMTESVPGAKRLRGMLPPGTAVAHKTGTSGTAATNDIGIITLPNGNHLAIAVFVSD +SPADETTRESVIAGIAKAAWDTw +>[subseq from] Uncharacterized protein n=1 Tax=Bosea sp. Leaf344 TaxID=1736346 RepID=A0A0Q6KHF4_9BRAD +--RLDREIAALEQRSQGRLGVALLDLRDRELW-SHRGAESFPMQSVFKLPLAIAVLQAVE +AGRLKLDQPITIHRREFSLHSPLAKAFKGESYPVRELIRLAAGESDNTAADILMREIGGP +KTVTAMLKAGDIAGISVDRYEREFQPAALKDKRDASTPEASVLFLEAQAKGNWLRDPAHS +RLIDIATDSPTGPKRIKAGLPSGARFAHKTGLGLNHATNDIGVVRLPDGRAFAIAVYLAG +SRADEATREATHAAMARLAVA-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides gallinarum TaxID=376806 RepID=UPI0003A1516F +-qALKERIAGFLKEKKATVGVAVLADGDETVL-QHNDRVRYPLLSVFKFHVALAVLDKMN +RQDTALDSIVHVKASQLHPYSPLRKKYAGQDISLKELLQYSISQSDNNACDILIEYAGGI +GHIHEYIKGLGISGFNLSETEDSMHRDPQRTYLNWNTPSEMVRLLKIAYEKTLFAPRYKD +FLWKIMAETSTGSNKLKGLLPSGVTVGHKTGSSDRTADNDAGVVIMPDGRKYYIAVFVMD +SSETDEENAAIIARISRMIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. RIFCSPHIGHO2_12_FULL_65_19 TaxID=1802172 RepID=A0A1G3KM02_9SPHN +---LSDRIRELWRTFPGKTGIAVQRIDGEWTL-SERGGELFPQQSVSKFWVALTVLDAVD +QGRLSLDQRVRIGPEDLTLYQPLAARVRSQGMTVRELIETAITHSDNTANDSLLRTVGGP +AAVRAFIAKKDLGAIRFGPGERLLQSNYLANPVDGASPAAIASALTRLARGTLLSPESTE +YLQDVMSRTRSGPRRLKAGLPPGWKFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGS +TTAGIPARMALMQAVSSAVAEY- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SNM6_9BACT +-sELENRIDSLLNRKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Beta-lactamase n=2 Tax=Novosphingobium resinovorum TaxID=158500 RepID=A0A031JS27_9SPHN +-----QQLAAVANASQGRIGVAAMDLSSGRMV-DVLGDQRFPMASTSKIAIAATFLEGVD +KGKWSLSSEFPLMVPVGSASSAIAPVRPGEYMSATRLIELMITRSNNYATDALLKVIGGP +KAVNAWIQRAGIDDWHIDRDIATLVRARVVDKRDSATPKAMVNLLSGIYQGKWLSPSSRN +VLLGAMSRCLTGKRRIPAGLPAGVEVSHKTGSLNN-TSSDVGIIQTPDGRVFAVAIYVTG +QG-GRPGRETRIANIARTIYNGy +>[subseq from] class A beta-lactamase n=1 Tax=Empedobacter falsenii TaxID=343874 RepID=UPI00056E3E61 +-eSLRTEINQILSSKNLTAGISLKNIENKDTL-SINGNQMMPMMSVFKFHIALAVLHEVD +QNKLQLNQRFFIKKEDLLPWSPILEDYPEGILTLDQLLRYTVSHSDNNGCDILLKIIGGT +KTVQNFINKQGIKDFIIKVNEQEMQT-WDNLYLNTTSANATTKLLEKFYATKVLKKNSTT +YLYQLMVETSRGLTWMKAGLPENTELAHRTGISDRVAMNDIGIIKPINHQPIILSIYLKN +ITEERTETEKVITDITKAVWNYy +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. FSW06-99 TaxID=1739113 RepID=A0A117V3C0_9SPHN +--AIQQNVEAIIARGRGRIGVAAADLDGGGQV-LIHGDMPFPMASTVKIAVAGTFLSGVE +AGRFRLDQSFPMMMPVAAREHGEARLRPGPVMSAQQLMELMITRSDNHATDGLITAVGGV +GAVNAWLAKVGIVGQHLDNTIATMVRATTIDTRNASTPRAMLALLAAIDRGGALSPQSRA +VLLDTMTRTSTGKNRMRAGLPEGTVFAHKTGTLQ-GVTDDVGIIRLPDGRHLALAVFITG +PEG-HTPHASMIAQITRALYDGy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=B2ZTR1_ACIBA +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDSVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAESSRTNEAIIAQ--------- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Novosphingobium TaxID=2644732 RepID=A0A258V622_9SPHN +---IQQQVAAIAAEGRGRIGVAAMDLDGGGQI-FVNGDMPFPMASTAKIAVAATFLEQVE +KGNYSLDQQFPMMLRVVEKASPEAPLRAGSVMTAQSLMELMITRSSNEATDGLIKVVGGY +ENVNRWLTRNGITGQRLDHTMATLVRARVIDTRTSSTPRSMIALLAAIDRGGVLSPESRA +VLLDTMTRTSTGKTRIRAGLPEGTLVAHKTGTLS-GVTDDVGIVRLPDGRHLAVAFFVTG +PEG-HAAHAKLIARMMRTIYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter sp. Alg231-14 TaxID=1922225 RepID=UPI000D54E482 +-------LRIIEAQMGGALGVELFDTQTGLSI-GLNSGMRFGHCSSFKLSLAALVLARNA +AGADDADRIVTWEESDLMFVSPFTTERLNEGASLRELAEFTQKYSDNAAANILLREVGGP +AALTAFWRSIGDGTSRLDRIEPHLNNVPSTEIRDTTTPSVMARTVAKLIYGDVLPDAEKA +TLRQWMVDTSTGTRRVRAGLPGDWRAGDKTGTSIGSLYVDIGFVENPSRGPITFATYLRM +PNESDPAAEAALAQVGEVLT--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SIY2_9BACT +-sELENRIDSLLNRKKATIGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. QXT-31 TaxID=1357916 RepID=A0A1P8WZ37_9SPHN +---LDDRLFEIWKAFPGKTGIAVQRIDGEWTL-TQRGNELFPQQSVSKLWVTLAVLDAVD +NGRLRLDQNVRIGPEDLTLHQPIAARVQSQGMTVRELIETAITQSDNTANDSLLRTVGGP +DAVRRFIDKKDLGAIRFGPGERLLQAAYRADPPDGASPAAIANALTKLARGNLLSPESTQ +YLLGVMTRTKSGPQRLKAGLPAGWTFLHKTGTGQTVGYNDIGIATAPDGTRYAIVVLMGE +ASSPVPARMATMQSVSRAVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI00119D7130 +-----KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNTP +--TSELNKKIAISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI +KGFQQALIHRGDHISNPQRLEPDLNLYDPQSTDDTTTPKRAATTLNHLLQSENMSKANLE +LLKHTMIHNETGDTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK +SDKDAKPDDKVIQTAAETAIK-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercorirosoris TaxID=871324 RepID=A0A413H2G9_9BACE +-kELEQQIGQVLKDKKATVGVAVLANDTIVA--LHNNQIHFPLFSVFKFHVALAVLDKMD +KGHVSLDSIMEIKAAQMLPYSPLRQKFPDRDISLGELLKYSISLSDNNACDVLIDYVGGI +DKVNSYIKSLGLKDFNLAANEELMHRDVATQYQNWSTPEAVVRLLNIADKQTLFATGYKD +FLWQILKETSTGTDKLKGELPPDVIVGHKTGSSDKTADNDAGFIILPDGRKYYITVLVME +SQETDRENAAIIARISKIVYD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A519KIB8_9CAUL +------DLSALEARNGGRLGVCIQG--DAGAV-QWRPDERFLYCSTFKLFLAAATLQRVM +QGEEQFDRQVPVIATDLLPHAPMTESAVGGTLSIRDLCRAAVEFSDNPAANILIRELGGL +DALRAWYRSKGDTFTSIDRLEPQLNRL--DGDKDTTSPAQTVRNLGAILTGT-LSGLEFK +SLMGWLQASPTGPNRIKAGVPAGWTVWHKTGTGAAGPTNDIGYLIDPDVGQFMIAVYYDA +PVVPIPEQETIIAEATRIALK-- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sediminis TaxID=707214 RepID=A0A512AIB5_9SPHN +--AIESQVSAIVAQGRGRIGVAAVDLDGGGQI-MINGDMPFPMASTAKIAVAATYLSGVE +QGRLRLDQQFPMMMPVAESRGSVAAVRPGVVMTAQSLMERSITRSDNHATDGLIAAVGGI +GAVNTWLSRTGISGQHLDHTMATLVRATTIDTRTSSTPRAMVQLLAAIDRGNALSPESRA +VLLDTMTRTSTGRNRIRSGLPEGVVFAHKTGTLS-GVTDDVGIVRLPDGRHLAIAIFVTG +PEG-HTAHAGMIAQIARVLYDGy +>[subseq from] Beta-lactamase class A n=1 Tax=Moheibacter sediminis TaxID=1434700 RepID=A0A1W2BUY7_9FLAO +--NLRNEINQLISSKNLTAGISIKGIEVKDTL-SVNGNLSMPMMSVFKFHIALAVLNEVD +KGKLKLNQKIFVKKEELLSWSPIREEFPQGNLTLDQLLRYTVSHSDNNGCDILLRLIGGT +ETVQKFINLQGIKDFTIKVNEEEMS-NWDNLYLNTTSPLASTELLEKFYKGEILKKKTTK +YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISNTNAMNNIGIVKLPNGKHYILSIYLTE +IMEEREVTEKILADIAKATYNYf +>[subseq from] Beta-lactamase family protein n=1 Tax=Bacteroides fragilis str. DS-208 TaxID=1339276 RepID=A0A015VGH3_BACFG +---LKTQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLETRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNKNLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNACNDIGFILLPSGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AKZ9_ECOLX +------------------------------------------------VMAAAAVLKQSX +XQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYG------------------------ +----------------------- +>[subseq from] Beta-lactamase n=5 Tax=Bacteroides TaxID=816 RepID=E0WMY1_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLETRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] serine hydrolase n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000C800526 +--SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD +AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI +EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGTLMAMVSQGNLLNMASRD +RILDIMRNTVR-NHLLPTGLEQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR +PNND-PRAEKLIASISKATYQQf +>[subseq from] Beta-lactamase n=2 Tax=Burkholderia gladioli TaxID=28095 RepID=A0A2S4NDN2_BURGA +hdALQATLERFAQAAPGTLGVVVLDLERPARW-QVNGTLPFPMMSVFKAPLGATVLDLAE +QGRLPLGQRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP +AVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR +RLLGLLQDQTQ-PRRLRAGLPPGVTFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA +SRASRAERERLFADLARAVAS-- +>[subseq from] serine hydrolase n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000C802E56 +--SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD +AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI +EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGTLMAMVSQGNLLNMASRD +RILDIMRNTVR-NHLLPTGLEQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR +PNND-PRAEKLIASISKATYQQf +>[subseq from] Beta-lactamase n=1 Tax=Fischerella thermalis TaxID=372787 RepID=G6FVR1_9CYAN +--SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD +AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI +EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGTLMAMVSQGNLLNMASRD +RILDIMRNTVR-NHLLPTGLEQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR +PNND-PRAEKLIASISKATYQQf +>[subseq from] serine hydrolase n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000C7FF3BA +--SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD +AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI +EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGTLMAMVSQGNLLNMASRD +RILDIMRNTVR-NHLLPTGLEQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR +PNND-PRAEKLIASISKATYQQf +>[subseq from] TLL2115 PROTEIN n=1 Tax=Synechococcus elongatus TaxID=32046 RepID=UPI000181CD1C +--NLQQQIQQLVSRQNLTAGLYFFNLDSGASL-NVGGDQVFPAASTIKFPILVAFFKAVD +EGRVTLQERLTMRPDLIAPEAGTLQQKPNSQYAALEVAELMITISDNTATNMIIDRLGGA +AELNQQFQEWGLENTVINNPEPDMKGT------NTTSPRDLATLMLKIGQGEILSPRSRD +RLLDIMRRTVT-NTLLPAGLGKGATIAHKTGDIGI-VVGDAGMVDMPNGQRYVAAMMVKR +PYND-PRGSELIRQVSRMVYQAf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=A0A415K6Q4_9BACE +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +ETVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRTYSIAVFVKD +SEENSQANSKIIADISRIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. QSSC1-22B TaxID=1860125 RepID=A0A1A7QI98_9SPHN +---FERRIAELADGSSGRIGVAAIDLTTGQEI-AVLGDQRFPLASTSKIAIAATFLEGVE +QGRWSLRSEFPLLWARKSASSPVAPVAEGERMRASELIEIMITRSSNPATDALLRAVGGP +NAVNSWMRRNGMSEFNIDRDIATLVRAHHIDRRDSATPGEMLELLTGLYQGKFLSSESRR +VILGAMSRTRTGTRRIPAMMPASVRVSHKTGSLNN-TSSDVGFLEMPDGRTVALAIYVTG +QG-SRPAREAKIAAIARAIHDGy +>[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. HII-3 TaxID=2075565 RepID=UPI000CDA5B89 +-----QQLAAVANASQGRIGVAAMDLTSGRMV-DVLGDQRFPMASTSKIAIAATFLEGVD +NGKWSLSSEFPLLVPVASRSSAIAPVRPGEYMSAARLIELMITRSNNYATDALLKVVGGP +KAVNAWVERAGIEDWHIDRDIATLVRAKVVDKRDSATPKAMVKMLAGIYQGKWLSPSSRR +VLLGAMSRCLTGKRRIPAGVPAGVQVSHKTGSLNN-TSSDVGIIETPDGRVFAVAIYVTG +QG-GRPGRESRIASIARTIYNGy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Alistipes senegalensis TaxID=1288121 RepID=UPI00101C5688 +-eSLERALRAVTDSVRATVGVAVV-FGDGDTL-AVNGGRCYPMLSVCKFHQALAVLDRLD +RRGLPLTTRIPVRRSDLLPWSPLREACPGGGFTVAELLTYSVAQSDNNVCDVLFRFLGGT +EAVDRYIAGLGIGETVIVADEEMMHRHTDNQYLNRTTPLAAVRLLERFRRGELLSAAYGD +FLLETMFATGTGPDKLRGLLPADVAVAHKTGSSDRDADNDIGIVRLPDGRSYSIVVFVMD +SREDDRTNAAVIARISRLVYDY- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=A0A412E227_BACSE +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIRKLGINDFNLSETEDSMHWNPQKAYSNWSTPSEMVRLLKMADEKDLFAPVYRD +FFWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] Beta-lactamase n=1 Tax=Legionella feeleii TaxID=453 RepID=A0A378IY02_9GAMM +--QLVKKIYDIEKRSNAVIGITAIHIEKNKVI-GHNGNKRFFMASTIKLPIALAFLHLVD +QKKDSLNRVVNLGLNNVVPGSGTLHYLCERKMSLQQILKYMMANSDNSASDTLLQTVNGP +TYVTKRMHALGFKNIVINRSIIEMMMRFEKDPRDTTTPAEMAKLLVKIYKNEALSESSTK +VLMDIMEKCRTGRSRIRGLLPPYVKVAHKTGTWAFRFVSDVGIITLPNNGHIAIAVYVKS +RAVSNYTRSRAIALASRAIYDHf +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacteraceae bacterium TaxID=2026738 RepID=A0A2E2IVJ2_9SPHN +--SFEQRIAELADGDRGRIGVAALDLTTGEQV-AVLGDQLFPMASTSKIAIAATYLEMVE +QGRYSLTSEFPLLIAVRSPSSPAAPVREGNYMQAIDLIEIMITRSSNPATDALLAAVGGP +EKVNDWMRRQGINDFSIDRDIATLVRANWIDPRDAATPRAMVRLLQGLHRGDFLSDQSRR +VLLGAMSRTVTGRRRIPANMPAEARVSHKTGSLNN-TSSDIGIIESPDGRAIAVAIYVTG +QG-SRLNREARIASIARALYDGf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SUN6_9BACT +-----AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD +QGALNLEQISHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQGSDNNTCDLLFALIGGT +ETVQKDLKEWGISGINVRFTEDEMLRNHDLQYANSSRPSAMNALLRAFDEGKILNKDTQR +LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD +SKDSAPACEKVIASMARWLCTEw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A222UA54_ECOLX +------------------------------------------------------------ +---NLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAI----------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Croceibacterium ferulae TaxID=1854641 RepID=UPI000EB236C5 +---LQQQIANMADGGRGRIGLFAVDLASGEEI-AVLGDQRFPMASTSKIAIAATFMEGVE +RGRWSLSSEFPLMLPVASRSSAVAPVRAGEHLSARQLIELMITRSSNPATDALLKAVGGP +AAVNDWVHRAGIREFNLSRDIATLVRAASIDTRDSATPRAMVELLAGLHQGRWLSDSSRQ +VILGAMERCRTGTRRMRALLPTGVTVAHKTGTLNN-TASDIGFIKAPDGRTIAVAIYVTG +QG-GRPARDAKIANLARAIYDGy +>[subseq from] Beta-lactamase n=2 Tax=Rhodospirillales TaxID=204441 RepID=A0A1E4LHS4_9PROT +--RAEAEIARIAGFAEGAVGLAARHLGSGLAL-GHRADEGFPMASTVKVPLALAVLELVD +AGKLQLDQMVAVDPLEMNPSAPIGEEFLYPGLSLLNLLEPMITRSDNTATDVLFRLAGGP +AAVAAYLARLGVAGITPSRSVRDLLIAYSSDPRDQATPAGMVELLARLFHAEGISRAARD +TLLPIMGRTSTGLRRIEGRLPKGVAVANKTGSAS-GTTNDVGIVTLPGRGAVAMAVYVKD +SALPPAEREDVIADVARTAYDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Brevundimonas diminuta TaxID=293 RepID=A0A3D4DDP1_BREDI +------DLSALEARHGGRLGVSAAT--EGRSA-AWRGYERFVYCSTFKMYLAAATLLRVQ +AGQERLDRAIPVTQADMISHAPVTEPAVX-------------EVSDNPAANILIREMGGL +EALRSFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLLVDTPLSPASKT +LLMRWLVDTPTGQGRIKAGVPADWTVAHKTGTGGYGPVNDIGLILPPNAAPIAIAVYFHA +TKSTDAQREAVIADATRQALK-- +>[subseq from] Beta-lactamase n=2 Tax=Akkermansia muciniphila TaxID=239935 RepID=A0A2N8I0L6_9BACT +-----SAVQELAHSLKARVGMAAEMLDTGETV-AVGDEADYPMQSVVKFVLALSVLKRVD +QGVMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP +QAVQKDLKEWGIDGINVRFTEDEIHRNRDLQYANSSRPSAMNSLLRAFDEGKILKKGTQR +VLWDIMAGCSTGHERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD +SKDSESACDRMIASMARWLCMEw +>[subseq from] class A beta-lactamase n=1 Tax=Chakrabartia godavariana TaxID=2056873 RepID=UPI0010FAD5A8 +---MVAALRAIWSAFPGKAGIAVMKTDGSWMV-SYRGDEPMPQQSVSKLWVAIAVMDAVD +KGQLSLDDQVTLKKSDITLHQPIAGLIGPNGTTIANLLKRAMTQSDNTANDFLMRRVGGP +TAIRELIASKRLGAIRFGPGERHFQARYVADPMDGATPAAIARSLARLKRGELLSAQSTR +YLLNVMESTETGRARLKAGLPAGWKLAHKTGTGQTAGFNDVGIMIAPDGTSYAVAVMIAD +TTAPVPTRQKLIQQVAITVAA-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0R5RPQ7_9BACT +-kELEQQIGQVLKDKKATVGVAVLANDTIVA--LHNNQIHFPLFSVFKFHVALAVLDKMD +KGHVSLDSIMEIKAAQMLPYSPLRQKFPDRDISLGELLKYSISLSDNNACDVLIDYVGGI +DKVNSYIKSLGLKDFNLAANEDLMHRDVATQYQNWSTPEAVVRLLNIADKQTLFAAGYKD +FLWQILKETSTGTDKLKGELPPDVIVGHKTGSSDKTADNDAGFIILPDGRKYYITVLVME +SQETDRENAAIIARISKIVYD-- +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma sp. BT328 TaxID=2692134 RepID=UPI001410066B +--RLEQELIRLSDISGGKVGICAVHLESGKTI-SQNGKDHFPMASSYKVAIATQLLTRVD +SGSITLDQLIPITKNDLHPGSGMLS-----SLSVRSLLELMLLISDNSATDVCLRLAGGP +DAVNGCMKRLGIDGLQVNRPTAWLIAAFENDIRDTSTPEAMTLLLSKLYMQSVLKPDSKA +LILDIMKRCETGLARLKGALPPDTEVLHKTGTIGL-TASDVGIITLPDKGHVAISVFVKS +SKKDGALRERAIAEVTRTIYDYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TCM1 TaxID=453246 RepID=A0A196M7M5_9SPHN +--KLLAEFARFATLSDGSVGIAVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRIFALVD +AGELRLDDQLALDPALASEGIAWMFSRPGASLSVDRLLELMLQKSDNNATDVLVARAGGP +QAITGFVAKLGVNGLRVDSDTAHLLYNFAMDPKDTSTPSAMLDLITAYASGRALSAASTQ +RLFTIMAHCETGKARIVGMLPPGTAVAHKTGSLN-GTGNDVGVVRLPDGRRFAVAVFVMK +DSKGHRSRDRIIAEAARAAYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroides fragilis CL05T12C13 TaxID=997881 RepID=I9VY34_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TINNDIHYPMMSVFKFHQALALADCMH +HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTIGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=Bacteroides TaxID=816 RepID=A0A412VKU6_9BACE +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVRECAIVGTETAMHKDLNLCYQNWTTPLAAAELLEIFHKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRIYSIAVFVKD +SEENSQANSKIIADISRIVYEY- +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=UPI0004528402 +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TINNDIHYPMMSVFKFHQALALADYMH +HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides fragilis TaxID=817 RepID=Q45116_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TINNDIHYPMMSVFKFHQALALADYMH +HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=Nitratireductor aquibiodomus RA22 TaxID=1189611 RepID=I5C6Q8_9RHIZ +--TLSQTVERIESTLGARVGIVIRDTGSDWRW-SHRAEERFLMNSTVKALICGGVLAELD +KGMLTLDQTLPIRQFDIVSYSPVTQKHVGKAMSIADLCLATLDISDNAAANLLIGRLGGP +KAVTAFLRSIGDPVSRLDRLEPKLNAFAPGDPRDTTTPAAMTETWHALLLGDVLKPASRT +QLIEWMSH---------------------------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter troitsensis TaxID=292222 RepID=UPI00070A2B8C +---LEATVAQIANGSAGRIGVYAVDLASGREV-SVLGNQRFPMASTSKIAIAATFLEGVE +KGRWSLTSEFPLMVPVASPFSGSKAPRPGQYMKAIDLIEIMITRSSNPATDALLAVVGGP +AAVNNWASRNGITDFNITRDIATLVRAHRIDVRDSATPQAMVQLLAGLYQGKFLKESSRK +VILGAMERCRTGTRRIPGMLPDGARVAHKTGTLSN-TASDIGIIHTPDGRAIAVAIYVTG +QG-SKPARDAKIASIARALYDGy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A346TJ63_KLEPN +------------------------------------------------------------ +-----------------------------GTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLA---------- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Parabacteroides goldsteinii TaxID=328812 RepID=UPI00101CD657 +-eQLKANIQEIIKDKKARIGVGII-LNGKDTV-TINNEDRYPMMSVFKFHQALAVLNYLQ +QNNLPLDTPIRIEKEDIIEYSPLRDKYPQGNLPINELLKYIIQLSDNIACDVLFKYIGGP +SVADKYIRSLGIQQFSIVITEDDMHQDLSACYLNWSTPLEAARLLEILLTRSLFKDEYQE +FLKNIMIECETGKDRLPQLLKTDAVIGHKTGTSDQNGTNDIGFVLLPNGSRYTVAVFIKD +SNESMETNAKIISSISEVIYKYf +>[subseq from] Serine hydrolase n=1 Tax=Deltaproteobacteria bacterium HGW-Deltaproteobacteria-21 TaxID=2013749 RepID=A0A2N2GZ94_9DELT +--RLRSRVESAIPPSQGVVGVSIKHMESGIVL-AVHGDEPFPMASTFKLPLLVELYAKEK +EGAFKWDDLVEISSTDQHLSSGLTALYDTPGLSIRNLANLMIIASDNSAADICLSKVGGP +SKVTAGMRKLGIEGIRIDRSCQELILRLAADPADSATPDAMVALLERIWQGRAVDPAASD +AMMKTLNRCRTGANRIRGLLPPSTDVAHKTGTLG-GVVNDVGIIALPDNGHVAIAVMCKR +TRAPRDQVERVIADIARYAYDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Syntrophus gentianae TaxID=43775 RepID=A0A1H7VZG4_9DELT +---LEGEIKRLAAMAGGTVGVSALHIESGQLF-SFHGGVRFPMASAYKIPIAVQLLRRVD +QGEIRLNSIVTLTSHDIHPGSGKLIKTFKKKYSVRELLELMLLVSDNSASDAILKLAGGP +EAVTRAMKDLGIEDITVSRSTLNMLARFYTDLRDTATPDAMTSLLAMIYDGTVLQPETTS +VLLKIMERCQTGNSRIKGLMPPGMTVANKTGTIGPGMVNDVAILTLPEGGHVALTIFIKI +SNRSVARQELAMAQMARYLYDYy +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=A0A3E5IJF1_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] FTU family class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI0003E76FFE +--QLDDSFKNLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM +HNQGFLDKKIPINQDDIGKYAPITAKNAGKTLTISQLNYAAI-LSDSPASNILVRELGGL +QNLNKFIKKLGDNDTIITADEPEINYTQPHSNINKITPKAITKDIYKLAFGNILDKKHKD +IFIKYLQDNNTGANRIAFGMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN +PNKNAPSNEEIIQQAAKLIAN-- +>[subseq from] Beta-lactamase family protein n=1 Tax=Bacteroides fragilis str. 3783N1-6 TaxID=1339310 RepID=A0A0E2TP44_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SMT0_9BACT +-qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN +REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI +GHIHQYIKKLGINDFNLSETEDSMHRNPQKAYSNWSTPSEMVRLLKMADEKDLFAPVYRD +FFWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVLIMPGGKKYYIAVFVTD +SSETDEENAAIIAHISRMVYDE- +>[subseq from] class A beta-lactamase n=1 Tax=Granulicella sp. S156 TaxID=1747224 RepID=UPI00131CB206 +--TLHQQISSIAQDAQGKVFVACSLPGVALDC-DLNAHGHPPMQSTFKLPLAIVVLQQVE +RGKLALDQPIRFLPSDRYPYSPLQDAHPDANVPLSELLQLAVGKSDNTAADILLRILGGP +EVVQDSLNKLGLRTIHVRDSERGLHDDFQAQYRNDAEPAAMVALLRLLADHSPLNAEHTA +LLNRWMTESTTGLHRIKGLLPADTLVAHKTGTSGERANNDVGLITLPNGHRLALAVFVID +SRADETTREAVIARIAKVIYDQ- +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SMV6_9BACT +-sELENRIDSLLNSKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. PhB55 TaxID=2485106 RepID=UPI001066187A +---FGKQLASVANASQGRIGVAAVDLSTGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD +KGKWTLSSEFPLMVPVPSASSAVAPVRAGTYMSARQLIELMITRSNNYATDALLKVVGGP +SAVNAWVRRTGIDEWHIDRDIATLVRAKVVDKRDSATPIAVVELLSGIYQGKWMSKQGRD +VLLGAMSRTVTGKRRIRAGLPAEVSVSHKTGSLNN-TSSDIGIIETPDGRAYAVAIYVTG +QG-TRPNREARIASIARAIYEGy +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. PhB57 TaxID=2485107 RepID=A0A4R3TC95_9SPHN +---FGKQLASVANASQGRIGVAAVDLSTGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD +KGKWTLSSEFPLMVPVPSASSAVAPVRAGTYMSARQLIELMITRSNNYATDALLKVVGGP +SAVNAWVRRTGIDEWHIDRDIATLVRAKVVDKRDSATPIAVVELLSGIYQGKWMSKQGRD +VLLGAMSRTVTGKRRIRAGLPAEVSVSHKTGSLNN-TSSDIGIIETPDGRAYAVAIYVTG +QG-TRPNREARIASIARAIYEGy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=unknown TaxID=N/A RepID=UPI00143CA456 +-nQLGAALEALLNTKKALIGVAIDGPKDGDSI-RINADMHYPMQSIFKLHIALTILAEVD +KGNLSLNQTVLIKKNELLPWSPIREDYPEGALSLAKVLEYTVALSDNAGCDALLRLLGGP +EKIENHFHNLGFTDFEVKINEEEMQNNWDKQFLNWTTPTESNRVLNAFFTQKLLSNDSHT +FFWDVLKNTKTGKKRLRGLLPKETIVAHKTGYSGSAAVNNVGIVYLPNGDTFTISVFITN +STEDTATNERLIAEICKAAWDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caecimuris TaxID=1796613 RepID=UPI00138F14D5 +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGYNDIGFVLLPDGRTYSIAVFVKD +SKENSQVNSKTIADISRIVYEY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL02_ECOLX +-----------------------------------------------KVMAAAAVLKXSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGXKTGSGGYG------------------------ +----------------------- +>[subseq from] Beta-lactamase n=10 Tax=Bacteria TaxID=2 RepID=A0A127SAJ7_9BACT +-sELENQIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Beta-lactamase n=2 Tax=Altererythrobacter ishigakiensis TaxID=476157 RepID=A0A562US25_9SPHN +--SFERRIAQLADGSRGRIGVAAVDLTTGEEI-SVLGDQLFPMASTSKIAVAAAYLEQVE +QGKYSLTSEFPLLIPLRSASSPAAPVREGNYMAADQLIEIMIARSSNPATDALLRAVGGP +EAVNNWVRRQGIEEFSIDRDIATLVRSMHIDRRDAATPRAMIQLLQGLYQGKFLSDESRQ +VILDAMAKTRTGKRRIPAEMPDYVEVMHKTGSLNN-TSSDIGILEGPNGHAIAVAIYVTG +QGA-RRAREARIASIARALYDGf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides uniformis TaxID=820 RepID=A0A3E4XI36_BACUN +-sELENRIDSLLNGKKTTVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. 32-60-15 TaxID=1970410 RepID=A0A258I0E6_9SPHN +--YIQQQIAAIAAEGRGRIGVAAMDLDGGGQV-FVNGDMPFPMASTAKIAVAATFLEQVE +KGTYRLDQQFPMMLRVRETLGPVAPLREGTVMTAQSLMELMITRSHNEATDGLINVVGGY +ENVNRWLTRNGITGQRLDHTMATLVRARVIDTRTSSTPRAMIALLAAIDRGGVLSPESRA +VLLDTMTRTSTGKTRIRAGLPEGTLVAHKTGTLW-GVTDDVGIVRLPDGRHLAVAFFVTG +PEG-HAAHAKLIARMMRTIYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus chromogenes TaxID=46126 RepID=UPI000D1CCC02 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLR-------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Listeria cornellensis FSL F6-0969 TaxID=1265820 RepID=W7C8Y6_9LIST +---------------------------GKQTI-NFNAEERFAYASTFKAIAGGILLKNLT +--DEQLNKRFTFSKEDLVDHSPITEKHVASGMTMKELINASMTYSDNTAANLTLQQLGGP +KGFEKELLKIGDKTMKPVRYEPELNDAVPGDIRDTTTPEAMAKTLAYLLTNGNLPADRLA +YFKQTLIANTTGGTLIRAGVPNGYVVGDRTGAGSYGTRNAIAMIYPKNKKPLVWVIFSKK +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Fischerella muscicola CCMEE 5323 TaxID=2019572 RepID=A0A2N6JZ96_FISMU +--SLKTNLQSLTSANNLTPGVFVVDLENGSYV-DINASASFPAASTIKIPILVAFFQDVD +AGKIRLDEMLTMQKEMIVGGSGDMQYKPAGTFKALEVATKMMTVSDNTATNMLIARMGGI +EALNQRFRSWGLNTTAIRNQLPDLQGT------NTTSPKELGNLMAMVSQGNLLNMTSRD +RILDIMRNTVR-NHLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVAVMVQR +PNND-PRAEKLIGSISRAAYQQf +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Methanosarcina mazei TaxID=2209 RepID=A0A0F8JIU6_METMZ +-------------------GYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTL---- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured Sphingopyxis sp. TaxID=310581 RepID=A0A1Y5PVT2_9SPHN +---LDDRIFELWRAFPGKTGIAVQRIDGEWSL-SQRGDELFPQQSVSKLWVALTVLDAVD +QGRMTLDQRVHIGPEDLTLHQPLAARVRAEGMSVRDLIETAITHSDNTANDSLLRTVGGP +EAVRAFISKKDLGAIRFGPGERLLQAAYLANPPDGASPEAIASALTRLARGTLLSPDSTE +YLLDVMSRTRSGPRRLKAGLPAGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGD +TNASVPARMALMQAVSGAVADY- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=A0A415HQU1_9BACE +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFCKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEENSQANSKTIADISRIVYEY- +>[subseq from] Serine hydrolase n=1 Tax=Aestuariisphingobium litorale TaxID=2339262 RepID=A0A419MUM9_9SPHN +---MVAALRAIWSAFPGKAGIAVMKTDGSWMV-SYRGDEPMPQQSVSKLWVAIAVMDAVD +KGQLSLDDQVTLKKSDITLHQPIAGLIGPNGTTIASLLKRAMTQSDNTANDFLMRRVGGP +TAIRELIASKRLGAIRFGPGERHFQARYVADPMDGATPAAIARSLARLKRGELLSAQSTR +YLLNVMESTETGRARLKAGLPAGWKLAHKTGTGQTAGFNDVGIMIAPDGTSYAVAVMIAD +TTAPVPTRQKLIQQVAITVAA-- +>[subseq from] Beta-lactamase n=6 Tax=Bacteroides fragilis TaxID=817 RepID=Q57509_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLETRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] Beta-lactamase family protein n=1 Tax=Bacteroides fragilis str. 2-F-2 #4 TaxID=1339280 RepID=A0A015ZMI1_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLETRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] Class A beta-lactamase n=1 Tax=Ponticaulis sp. TaxID=2020902 RepID=A0A2E0UAN6_9RHOB +------------------------------------------MCSSFKWLLAALVLKQVD +AGDLLLEQTVYFTREDMVPHAPVTESALGLGLTVAELCEATVQTSDNPAANLLLRLIGGP +EGFTEMLRADGADTTRLDRWEPELNANTPGDPRDTTTPNAMVSLMGYYLFGAGLSGRSAD +LVKEWMTGATTGLDRLRAGFPDYWISGDKTGTSSNDQTNDVAFAFQPSTQPVLISSYLNV +SDP--MTRDPVHAEIGQLVMK-- +>[subseq from] class A beta-lactamase n=1 Tax=Moraxella osloensis TaxID=34062 RepID=UPI00132E8E5A +-------LPSWENKLNAKIGMAVITASNNELA-SYRGNDFFPFNSTIKAFIGAYILHLVD +KGQLDLAQTLQIKATDLLEYAPQSKKFFEANISIAELSEAMITVSDNTASNLLLDTTGGL +KPFNDFLHQIGNSEVILVHNEPLLNRSHYGDKIDTAKPIAYTQALKNILMGDILSEQSKK +LLLTWLINDKVGDSLLRKHLPKDWQIGDKTGAGDE-SRNIVAIVWNSQKEAYFVSLFITQ +PYKSNNQKSVAIAEIGQAIYS-- +>[subseq from] Beta-lactamase n=2 Tax=Staphylococcus TaxID=1279 RepID=A0A3N0HUB2_9STAP +-----KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNTP +--TSELNKKIVISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI +KGFQQALIHRGDHITNPQTLEPDLNLYDPQSTDDTTTPKRAATTLNHLLQSENMSKANLE +LLKHTMIHNETGDTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK +SDKDAKPDDKVIQTAAETAIK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0G3FAD5_KLEPN +------------------------------------------------------------ +------------------------------TMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAA------- +>[subseq from] Beta-lactamase n=2 Tax=Akkermansia muciniphila TaxID=239935 RepID=A0A2N8HS92_9BACT +-----AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD +QGALNLEQIIHIRPEQLLKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT +GTVQKDLKEWGISGINVRFTENEMLRNHDLQYVNSSRPSAMNALLRAFDEGKILNKDTQR +FLWDIMAGCSTGATRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD +SKDSLPACEKVIASMARWLCTEw +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=UPI00125FA781 +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +ETVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRTYSIAVFVKD +SEENSQANSKTIADISRIVYEY- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. AM54-2NS TaxID=2292955 RepID=A0A3A5R1H7_9BACE +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALTDYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFCKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEENSQANSKTIADISRIVYEY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q849S7_KLEOX +------------KRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE +SNKEVVNKRLDINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP +EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA +QLVTWL------------------------------------------------------ +----------------------- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium jejuense TaxID=445960 RepID=A0A2X2VRR9_9FLAO +--EFKKVIETIIAHKKADIGVSIVTAGTKKEVtQINGNKPLPMLSTFKFPVALAVLHKVE +KGELSLQQKIYIKKEELLEYSPFREKYPEGNLSLEECIHWMMVYSDNNLTDILIRLIGGP +DYVQNFINS---KDIVIKNDEEGMHKDWDSQFINTITPNAAIRLLEQFYNGKILNKEHTK +WLYTVMINNATGTKRLKGKLPKDVKVAHRTGTSFTGAINNYGIIELSDKKRIYIAVFIHD +TFETFENSEAIIADIAKAAYNYy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=A0A5N0M834_9BACE +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALTDYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFCKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEENSQANSKTIADISRIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WPN8_9BACT +--DLTALIEKTAAPAKGRVGVFAVVLETGESV-DLDPDGQYPMQSVFKLPISMAVLRQVE +EGKLKLDQKVKVEKADYVRRSPLRDKNPNGAVTVEELIRLSIVESDGSASDVLTRLAGGA +GEIQAYLTGINIGEMIVANTEKEIGQDWETQYRNWASPEGAAALLRALHEKRGISEPHQK +LVLKFMVESVPGAKRLKGMLPAGTQVAHKTGTSGTAATNDIGIITLPNGKHLAIAVFVSD +SPADEATREGVIAGIAKACWDTw +>[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. FGD1 TaxID=2692619 RepID=UPI00136B4BF6 +-----QQLAAVANASQGRIGVAAMDLSTGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD +KGKWSLSSEFPLMVPVASRSSAVAPVRPGEYMTASRLIELMITRSNNYATDALLKVVGGP +KAVNAWIDRAGIEDWHIDRDIATLVRARVVDKRDSATPLAMVKLLSGIYQGKWLSPSSRS +VIMGAMSRCVTGRRRIPAGLPAEARVSHKTGSLNN-TSSDVGIIQTPDGRVFAVAIYVTG +QG-GRPGREARIASIARTIYNGy +>[subseq from] serine hydrolase n=1 Tax=Novosphingobium acidiphilum TaxID=505248 RepID=UPI00048CBBF7 +--AIQQNIESIVARARGRVGVAAADLDGGGEV-LIHGDMPFPMASTVKIAVAGTFLTGVE +QGRYRLDQSLPMMMPVAERGARSAQAPVRPGMSAQQLMELMITRSDNHATDGLISAVGGV +SAVNAWLARTGIVGQHVDSTIATLVRATTIDTRNASTPRAMLSLLAAIDRGTALSPQSRA +VLLDTMTRTSTGKNRMRAGLPDGTVFAHKTGTLQ-GVTDDVGIIRLPDGRHLALVIFVAG +PEG-HTSHAMLIAQITRALYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Francisella noatunensis TaxID=657445 RepID=UPI00132F7074 +--TLDDSFKNLEDKYHGKLGIYTVNTDDKTNI-SYNENYHFPICSIFKFLLVGAVLEYDM +QDKGFLDKKILITQDDIGTYAPVTGKNIGKTLTVSQLNYAAI-LSDNPAANILVREIGGL +EKLNKLVAKLGDKDTIIKNDEPKINHTKPDSDINKTTPKAITQDIYNLAFGNILDKKHRE +IFIGYLQKNNTGANRIAYSMPKNWTIGDRTGTCGYAATNDVTIIWPQNKPPFALSILYTN +PSLKAPSNEKIIQQASKLTVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Francisella noatunensis TaxID=657445 RepID=UPI0013627EBA +--TLDDSFKNLEDKYHGKLGIYTVNTDDKTNI-SYNENYHFPICSIFKFLLVGAVLEYDM +QDKGFLDKKILITQDDIGTYAPVTGKNIGKTLTVSQLNYAAI-LSDNPAANILVREIGGL +EKLNKLVAKLGDKDTIIKNDEPKINHTKPDSDINKTTPKAITQDIYNLAFGNILDKKHRE +IFIGYLQKNNTGANRIAYSMPKNWTIGDRTGTCGYAATNDVTIIWPQNKPPFALSILYTN +PSLKAPSNEKIIQQASKLTVD-- +>[subseq from] Beta-lactamase n=23 Tax=root TaxID=1 RepID=BLAC_BACUN +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sharifuzzamanii TaxID=2211133 RepID=UPI000DAF137F +-nELRNQLHQIISNKSATLGLSMKGIEDKDTL-SINGNLKMPMMSVFKFHIALAVLHKVD +EGKLNLTQEIFIKKKDLKEWSPMKVDYPEGNLTLDKILRYTVSHSDNNGCDILINLVGGT +KYIKKFINEQGIRDFVIKMNEDQMKT-WKNLYVNTTTPIATTELLEKFFKGEILKQETTK +YLYQLMVETSRGLTWMKAGLPENTELAHRTGISGTNAMNDIGIVKLPNGKHFILSVYLKD +ITEKREDTEKIIADLTKAVWDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=V5NA29_ECOLX +------------------------------------------------------------ +----LLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGNKTGSGGYGTTNDIAVI---------------- +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Novosphingobium sp. PP1Y TaxID=702113 RepID=F6IHB4_9SPHN +--QFEKQLASVAEASKGRIGVAAVDLATGRTI-EVLGDQRFPMASTSKIAIAATFLAGVE +KGKWSLTSEFPLMVPVASASTPIAPVRPGAYLSARDLIEQMITRSNNYATDALLKVVGGP +KAVNDWVHNAGIEEWHLDRDIATLVRAQVIDKRDSATPLAMVKLLNGIYDGKWMKAESRD +VILGAMSRCRTGRRRIPAMMPDGVTVSHKTGSLNN-TSSDVGIIQTPDGHAFAVAIYVTG +QG-SRPNREARIAQIARTVYDGy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides acidifaciens TaxID=85831 RepID=UPI0005CBD566 +--SLETQLKEAIKDKKAEIGIAVI-IDGKDTV-TVNNDTHYPLMSVFKFHQALALADYMG +KRNQSLDTLLTVEKSDLKPYSPLRDKYPEGGMSIAELLKYTLQQSDNNACDILFHYQGGP +DSANKYIRSLGIQDCEITHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRREPLFAKEYKD +FIYQTMVECQTGQDRLIALLDKGVIVGHKTGTGDRNGCNDIGFVVLPDGHTYSIAVFVKD +SEESSPENSKIIADVSRIVYEY- +>[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Sphingobacterium paludis TaxID=1476465 RepID=A0A4V3E1M2_9SPHI +--SLENQITSFIQDKKAFVAVAIQEGHHGDIV-QIHAEEKLPMQSVFKFHIAVAMLTEID +KGTFQLDQPITVSKEDLTPWSPLRDDYPQGAIPLSTLLTYMVAQSDNVACDVILKLLGGP +EQVDLFFKEKGVKNLAIKINEKTMQSNWEAQFQNWTTAEECNNLLKTYFYKKELSPESHS +FLWTVMKGTKTGLKRLKGDLPANTVVAHKTGYSGTEAAHDVGIIFLPDNKPLFISVFVSR +SKEELAVNEEIIARIARMTYDFy +>[subseq from] Beta-lactamase family protein n=1 Tax=Bacteroides fragilis str. 3986 N(B)19 TaxID=1339289 RepID=A0A015VDJ1_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNKNLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPGGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SKB4_9BACT +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium timonianum TaxID=1805473 RepID=UPI00083B73C9 +-sTLEQKINTIIKGKQATVGVSVLGFEDPIRY-SQNGNKKLAMMSVFKFHVACAALDLVD +KGKLSLDQKIFIKKSDLYEWSPYRVKYPEGNATVSEIIDYTVALSDNNLCDILIELVGGT +QAVQKFMDFKGVKDFQIKYSEHGMANGWDSLYKNYTTTNSTVDLLKKFYEGKLLSKGSTD +YLMQIMLDTKTGANKIVEQLPKGTPAAHKTDSSGRKAENDMGIITLPNGKHYAIAIYVSN +SKESEAENCKIISNISKAVWDNf +>[subseq from] class A beta-lactamase n=1 Tax=Mucilaginibacter sp. HC2 TaxID=2714892 RepID=UPI00140A2F6D +-qSIRQQVIKIASGIKAQVGVSAMIVETGDTV-NYRAGDKFPMQSVYKLPIAIAVLHQVE +LGRLSLNQQVKVSPTEIIPVSPIRDRYAHGVLSILELLRYNVSDSDGSACDVLIRILGGC +QKINQYIHSVGIRDIAISTTEMVQVSDDWVQYRNWVKPEAMLLLLKKFYAGQLLNRSHNE +LLLNLMIKSGPGAKRLKGMLPAQAVVAHKPGSSGTRTTNDVGIITLPNNKHLLIAVFIAD +TYADTEEREGVIAQIAKAAWDNw +>[subseq from] Beta-lactamase n=2 Tax=Novosphingobium pentaromativorans TaxID=205844 RepID=G6EB29_9SPHN +--QFEKQLASVAEASKGRIGVAAVDLATGRTI-EVLGDQRFPMASTSKIAIAATFLAGVE +KGKWSLTSEFPLMVPVASASTPIAPVRPGAYLSARDLIEQMITRSNNYATDALLKVVGGP +KAVNDWVHNAGIEEWHLDRDIATLVRAQVIDKRDSATPLAMVKLLNGIYDGKWMKAESRD +VILGAMSRCRTGRRRIPAMMPDGVTVSHKTGSLNN-TSSDVGIIQTPDGHAFAVAIYVTG +QG-SRPNREARIAQIARTVYDGy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SN23_9BACT +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A522CNG4_9CAUL +---LQKAVDAIAATAPGMLGVGLMNLESGQSF-LTNPDRPFPMQSVFKLPLAAAVLGEVD +AGHLGLTTRLTILEDQLSPHSPIATAWPGRRYTVEELLEAVLIESDNTAADVLMSHIGGP +GVVTAWLIGKRVPEIRVDRYERELPARYMADPRDTSTPRGMLEFLQRLDRGELLSADSTR +RLTDLMSRCTRGAGRIRAGLRPGAFLAHRPGTSGSTVHNDVGVFTLADKRAYALAVFLSG +ATLDDTGRDRVIAQVASAAVR-- +>[subseq from] Putative Beta-lactamase (Precursor) n=1 Tax=Streptomyces viridochromogenes Tue57 TaxID=1160705 RepID=L8P2T9_STRVR +------------------------------------------------------------ +---------VRYSRDDLVADSPVSENFVKTGMSLRGLCAATLWYSDNTAVNLLFDELGGP +DGLEKVLEEFGDDVTEMDRYEPDMSEGAPGDIRDTSTPRAMAGSLRAFLLGDALKADERE +LLRQWMTTNMTGRTLIRAGVPDGWDVADKSGTAGYGGRNNIAVVWPDDGNPIVMAVMSSR +DKQGAERDDALLAKAAAVAVK-- +>[subseq from] Serine hydrolase n=1 Tax=Altererythrobacter sp. Ery12 TaxID=2306996 RepID=A0A419R2R6_9SPHN +--ALERLVGRIADGSQGRIGVAAVDLVTGQQV-SILGDQRFPMASTSKIAIAATFMEGVE +QGRWSLSSEFPLMVPVRSASSAVAPVRPGQYFKAIDLIEMMITRSNNQATDALLKVVGGP +RAVNKWVRAQGIEEFQIDRDIATLVRAKQIDTRDSATPKAMVKLLTGLYQGKYLNEASRR +VILGAMERCRTGSRRIKALLPDSAIVAHKTGSLNN-TSSDIGVIKAPNGHAIALAVYVTG +QG-SRPAREAKIASIARTLYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=UPI000C1BBFEF +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKK +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDV------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Coxiella burnetii TaxID=777 RepID=UPI0011857F6F +------------------------------------------------------------ +----------------------MTKNHINGGITVSELCAAALTLSDNSAAKLLIKKLGGL +TAINAFARSIGDKQFELDRLEPQLNSAIPGDIRDTTTPEAMANSLKRLTLGDILAFPQRI +QLQTWLKNNTTGNAKIRAGVPKDWIVGDKTGSGGYGTTNDIGIIWPPKRAPIVVAIFFTK +NKKGAVSPDSIIERITRILM--- +>[subseq from] Beta-lactamase n=1 Tax=Francisella adeliensis TaxID=2007306 RepID=A0A2Z4XY48_9GAMM +---LDASFKKLEDKYSGKIGVYSINNTDKSLI-EYNENYHFPICSVFKLLLVGAVLHEDM +QNEGFLDKKILITKKDITNYTPITGKNIGKHLTISQLSFAAI-LSDNAAGNILIEQIGGL +NKLNLFIKNLGDENTIINNNEPKVNNTTPESNINKTTPKSITRDINELIFGNILDDKHKK +IFIKWLQDNNTGKNRIALNAPKNWIIGDKTGTCGYGSTNDVAILWSPNKNSIALGILYTN +PEKNAKNNEKIIQEATKLITN-- +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma terrae TaxID=1968276 RepID=UPI0013D7DE8A +--RLERELLRLSDISGGKVGICAVHIESGKTI-LQNSKDRYPMASSYKVAIATQLLSRVD +SGAISLDQLITIEKNDLHPGSGMIS-----TLSVRSLLELMLLISDNSATDICLRLAGGS +AAVNACMNRLGIEGLQVDRPTAWLIAAFENDPRDTSTPEAMTLLLTKLYTKPVLKPDTQT +LLLDIMRRCETGLARLKGALPPDTEVLHKTGTLGL-TASDVGIITLPDNGHVAISVFVKS +SKKDGNSRERAIAEVTRTIYDYf +>[subseq from] CblA family class A beta-lactamase n=1 Tax=Bacteroides uniformis TaxID=820 RepID=UPI00125E7B8F +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMRYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D5CAC6_ECOLX +---------------------------------------------------AAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTT---------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium guangzhouense TaxID=1850347 RepID=A0A2K2FZF1_9SPHN +-----QQLAAVANASQGRIGVAAMDLTTGRMV-DVLGDQRFPMASTSKIAIAATFLEGVD +KGKWSLSSEFPLMVPVGSASSAIAPVRPGEYMPASRLLELMITRSNNYATDALLKVIGGP +KAVNAWIERAGIDDWHIDRDIATLVRARVVDKRDSATPKAMVNLLSGIYQGKWLSPSSRN +VLLGAMSRCLTGKRRIPAGLPTDVKVSHKTGSLNN-TSSDVGIIQTPDGRVFAVAIYVTG +QG-GRPGRETRIASIARTIYNGy +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium barchaimii TaxID=1420591 RepID=A0A561HXT9_9SPHN +---FGKQLASVANASQGRIGVAAMDLSSGRMV-DVLGSQRFPMASTSKIAIAATFLEGVD +KGKWTLSSEFPLMVPVPSASSTVAPVRPGTYMSARQLIELMITRSNNYATDALLKVVGGP +SAVNAWVRRTGIEDWHIDRDIATLVRAKVVDKRDSATPIAVVELLAGIYNGKWMSKQGRD +VLLGAMSRTVTGKRRIRAGLPAEVTVSHKTGSLNN-TSSDIGIIETPDGRAYAVAIYVTG +QG-TRPNREARIASIARTIYNGy +>[subseq from] Beta-lactamase n=1 Tax=Nostoc sp. NIES-4103 TaxID=2005458 RepID=A0A1Z4S812_9NOSO +----KDAVQNLVAANNLSPGVFLVDLDTGSYV-DVNSTASFPAASTIKVPILVAFFQEVD +AGKIRLDEMLTMQQDMVAGGSGQMQKPVGTQYNALEVATKMITISDNTATNMLIARLGGM +DALNQRFRSWGLTTTVIRNQLPDLQGT------NTTSPRELANLMAMLNQGNFVSMRSRD +LMLDIMRRTAR-DNLLPSGLGAGARIYHKTGDIGT-MLADTGIIDTPTGKRYIAAVMVQR +PNND-PRAEKLISSISRAAYQQf +>[subseq from] class A beta-lactamase n=1 Tax=Prevotella oryzae TaxID=185293 RepID=UPI0004B91663 +----RKGINKIIKGKHATIGVAIYDTQTGNTL-NINGDKHFPMQSVFKFPIALNILTKVD +KGKMSLNDSIFITAKDLLPWSPIRDRYPEGNMPLSEIIRYTISQSDNNGCDILIHLLGGT +STVNSYISSLGLTEMKIKKTEAEQHITPSAQFYNWTTPTCAIQLLRLFHEKKILLSDSRD +FLFKTMTETSTG--SVKTEIPQDVIVAHKTGSAFY-VVNDIGVMQIPDNHTILYAIFIMK +SKESKENNYKIIADIAKVVYQ-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides uniformis TaxID=820 RepID=A0A413N2X4_BACUN +-sELENRIDSLLNGKKATVGIAVW-TYKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=Bacteroides TaxID=816 RepID=A0A5N4EU35_BACOV +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP +DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIADISRIVYEY- +>[subseq from] Class A beta-lactamase n=1 Tax=marine bacterium AO1-C TaxID=1905359 RepID=A0A1Q3GHK8_9BACT +-qALKEKINQVLKGKSATVGVAIQGVNATDTL-SINGNKHLPMQSVYKYHLAMAVLHQVD +QGKFRLDEKISISKKTVKAWSPLRKKYPNGAVALSEIIKYTVAWSDNVGCDLLFKLIGGP +KVAEAYMHKIGIQDIAIVDPEIKMQAKWKRQYKNWTTAKAANQVLQLFFKNNLLSPKSYN +FLLNVLKGTKTGKKSIRGLLPKDAVVAHKTGHSGTGALNNIGIVFLPGNSYFYISVLVSN +SMESSATNQKIIAEIAKLTWDYf +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. Rr 2-17 TaxID=555793 RepID=I9WD20_9SPHN +---FEQQLAAVAEASKGRIGVAAMDLTSGRMV-EVLGHQRFPMASTSKVAIAATFLDGVD +KGRWSLSSQFALQVPITSAFSTAVAPVRGGDMSAQQLLELMITRSNNYATDALLKAVGGP +SAVNAWIARAGVADWHIDRDIATLVRARVVDKRDSATPIAMVQLLSGIYQGKWLSPSSRN +VLLGAMSRCVTGKNRLRAGLPTDVLVSHKTGSLSN-TSSDIGLIQTSDGRVFAVAVYVTG +QG-SRPNREARIASIARTVYNGy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caecimuri TaxID=2516958 RepID=A0A4S2CY52_9BACE +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD +FIYQTMVECQTGQDRMVALLDKKVTVGHKTGTGDHNGCNDIGFVLLPDGRTYSIAVFVKD +SEESFADNSKIIADISRIIYEY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium MED-G03 TaxID=1986231 RepID=A0A2A5YFA4_9SPHN +--KLLAEFERFAALSDGTVGIAVRDLQTGETQ-SFNGDTLFPMASAYKVAVAGRIFALVD +AGELRLDDQLALDPALASEGIAWMFSRPGAALSVQRLLELMLQKSDNNATDVLVARAGGP +QAITRFVTGLGVNGLRVDSDTAHLLYSFATEIEDTSTPRAMLDLLSAYESGRALSADSTQ +RLFTIMAHCETGKHRIVGMLPPGTAVAHKTGSLN-GTGNDVGVVRLPDGRRFAVVAFVMK +DGKGHKARDRIIAEAARAAYDYf +>[subseq from] serine hydrolase n=1 Tax=Nostoc sp. NIES-4103 TaxID=2005458 RepID=UPI000BBC8B61 +----KDAVQNLVAANNLSPGVFLVDLDTGSYV-DVNSTASFPAASTIKVPILVAFFQEVD +AGKIRLDEMLTMQQDMVAGGSGQMQKPVGTQYNALEVATKMITISDNTATNMLIARLGGM +DALNQRFRSWGLTTTVIRNQLPDLQGT------NTTSPRELANLMAMLNQGNFVSMRSRD +LMLDIMRRTAR-DNLLPSGLGAGARIYHKTGDIGT-MLADTGIIDTPTGKRYIAAVMVQR +PNND-PRAEKLISSISRAAYQQf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Bacteroides fragilis TaxID=817 RepID=A0A2M9V5D9_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacC n=1 Tax=Fuerstia marisgermanicae TaxID=1891926 RepID=A0A1P8WHV6_9PLAN +-eTLAAKIQPLIDRHDGDVGVYVQHLTSGVKF-QHRPDAVMPTASLIKLPVMIEAYRQAD +AGTIDLDSMLTLHDSDKVPGSGILTTHFSDGLSLRDAIRLMIAYSDNTATNLVVDAI-GM +KATAETMEKMGFPETKLHSKVYRGSSRSQQYGLGSTTAADIVALLQQLHEGKLVSPKACD +DMKAHLLACED-KKKLPRFLPAGVKVAHKTGSVSK-SRCAAGLMYTRSG-PIAICVLTSN +NKGDKNAGDLLCSHIAKAACDYf +>[subseq from] Beta-lactamase n=2 Tax=Rhodanobacter sp. OK091 TaxID=1881037 RepID=A0A1M7BRP4_9GAMM +--RLQQTLDALARRAPGTLGVAVLDLQSGAEA-SVNGGQAFPMMSVFKAPVAAAVLWRID +EGKLSLQQQVTLTRADVLSGSPSIGAHFRGEFTVEQLLKAAVSESDNTAVDALVKVVGGP +QVVTAFLRVHGIDGMRVDLDEAGVGRAFLAAPYNRSTPDAAVMFLRKLHGNELLTPASTQ +HLLDLMAAQTI-PNRLRAGVPRGVGLADKTGTSYMASFNDIGILSGPNGHTVIVAAFLTD +SSASEAERNALFADIARAAATSf +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI0012965DA1 +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLEGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPDRLRVGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAAARAITAAy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=B2CD52_ECOLX +-------------------------------------------------MLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWYFA--------------------------------- +----------------------- +>[subseq from] Truncated beta-lactamase n=15 Tax=Gammaproteobacteria TaxID=1236 RepID=B9VVU8_ECOLX +------------------------------------------------------------ +-------------------------------MTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVTGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Kluyvera georgiana TaxID=73098 RepID=A0A3S7Q8H5_9ENTR +------------------------------------------------------------ +-------QRVEIKLSDLTNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLITHLGGP +GEVTAFARAIGDRTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRHLTLGNALGETQRA +QLVTWLKGNTTGAASIQAGLPKSWVVGDKTGSGDYGTTNDIAVIWPQGR----------- +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Myroides guanonis TaxID=1150112 RepID=A0A1I3QLD4_9FLAO +-eKLRDSIEAILRNKNAVVGVAINGMNESDSL-SIHGSRHFPMQSVFKFPIALTMLSEID +KGNFSLGQKVAIHKNELLPWSPIRDKHPEGALTIAEILRYTVMMSDNVGCDVLLRLLEKP +EVVENYIHKKGFNDFAVKINEEVMQNNWDLQFLNWTTPTEANNILRVFYEGNQLSKRSYD +FIWNVMKETETGKDRLKGQLPKGTIVAHKTGWSGSAAVNDIGVVFLPNGNHFYISVFVAD +SKEDTATNEKIIADITRLAWDYf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonadales bacterium BRH_c3 TaxID=1734408 RepID=A0A117S7Q7_9SPHN +--SFERRIAQLADGSKGRIGVAALDLTTGEEI-GVLDNQLFPMASTSKIAVAATFLEMVE +QGKYSLTSEFPLMMPLRSASSPVAPVRAGEYMPAHQLIEIMISRSSNPATDALLAVVGGP +AKVNDWVRRQGIKDFSINRDIATLVRASHIDKRDAATPRAMLELLKGLYQGKFLSAESRA +VLLDAMSKTRTGKRRIPALMPMGVTVSHKTGSLNN-TSSDIGIIEGPDGRAIAVAIYVTG +QG-SRLAREERIAAIARELYDGf +>[subseq from] Beta-lactamase class A n=1 Tax=Bosea sp. DSM 18164 TaxID=1881058 RepID=A0A1I1SX72_9BRAD +--KLDAGIKTIEQSTKGRLGVGLTDLKDRKSW-SYRGAEPFPLQSVFKLPLAIGVLQAIE +AGKLKLDQPITVTRNDLSLHSPLAKAFKGERYPLRELLARSTGESDNTAADLLLRLIGGP +QALTAILRDGGVTGISVDRYERVFQPATLTDKRDAASPESSIAFLEGLAKGTWLRDPANA +ALLDIMLEAKTGPNRIKAGLPAGARFAHKTGLGPNHATNDIGIVTLPDGRRFAIAVYLAG +AQVGEKEREAAHAAVARLAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Alistipes timonensis JC136 TaxID=1033731 RepID=A0A1H4AJ81_9BACT +--SLGRAVRAVADSVRATVGVAVV-FEEGDTL-VVNNACRYPTMSVYKFHQALAVLNRLD +RSGLPLTTRIPVLRSDLLPWSPLREACPGGGFTVAELLAYSVAQSDNNVCDLLFRFLGGP +EVVNRYIAGLGVGETEIAADEETMHRRTDNQYLNWATPLAAVRLLELFRRGKLLSAESGD +FLLKTMFATETGPDKLRGLLPPGVAVAHKTGSAFRDADNDIGIVRLPDGRSYSIAVFVMD +SREDDRTNAAVIARISRLVYDY- +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter indicus TaxID=374177 RepID=UPI00136E5AB9 +-sALESRIAQIANGDQGRIGVAAIDLSTGREL-SVLGDQRFPMASTSKIAIAATYLDGVD +KGKLSLSSEYPLMVPVSSKSSKIAPVKKGQYLSARELITLMLTRSSNSATDAILAALGGP +SVVDEWVHRTKITNFTLTRDIATLVRVSHIDTRDSASPKAMVRLLKGLYQGDWLSEQSRS +FLISTMEKCRTGTRRIRAQMPSTVTVAHKTGSLHN-TSSDIGIVTTPDGRSFAVAIYVTG +QG-TRANREAKIATIARAIYDGy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=A0A3E4NAI7_9BACE +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRIYSIAVFVKD +SEENSQANSKTIADISRIVYEY- +>[subseq from] Beta-lactamase class A VEB n=1 Tax=Pedobacter sp. CF523 TaxID=2135715 RepID=A0A3L9ZQ67_9SPHI +--TLKAQIQEVIKGKRATVGISIIANSFKDTI-NINADVHLPMQSVYKFPISLALLKEIE +KGKFLLQQKIVVTKKDLLSWSPIREKYPTGRMSIAEIMEYAVSQSDNNGCDILLRLIGGT +AQVENFLKQNQLNNISVKTTEEQAQKDWSLQFKNWSTAAALTHLLTRSYENKLLSNANYK +FIWKVMEQTTTGSKRIKGQLPVNTVVGHKTGTSGTAATNDIGVIKLPDGGLIFISVLVSG +SLESEQINEKIISDISRLAYEHy +>[subseq from] class A beta-lactamase n=1 Tax=Legionella rowbothamii TaxID=96229 RepID=UPI001055274E +--ALAKKIREIEKKSHIVMGITAIHIEKNRMI-THNSNQRFFMASTIKLPIAVAFLHLVD +EKKESLSRIIKLSSKNSVPGSGYLHHMFEKKISLQQILKYTLINSDNSASDSLLKAAKGP +EAVKKRMAALGFKDIHVNRSILEMFVRFQNDPRDTTTPNDMAKLLVKVYKNQALSETSTQ +LLMKIMEQCRTGRSRIKGLLPPGVKVAHKTGTWSSGFVSDVGIITLPNKGHIAIAVYVKS +QSASDYPRSRAIALASRAIYDHf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A520X2Y6_9SPHN +---FAQRIARLADGSDGRIGVAAIDLVSGEEI-SILGDQRFPMASTSKIAIAATFLEGVE +RGRWSLTSEFPLMVPVQSAFSSAAAPVRKGSMPAIDLIEIMITRSSNPATDALLRVVGGP +AAVNEWARRNGIREFSIDRDIATLVRAKHIDLRDSATPRAMVDLLSGLYQGRFLSAESRQ +VLLGAMSRTRTGTRRIPAMIPSSAQVLHKTGSLNN-TSSDVGIIKMPNGRAFAVAIYVTG +QG-TRGQREAKIASIARALYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas vulcanisoli TaxID=1658060 RepID=UPI0014243713 +--TLQPRLAALAHSAPARVGIAAIDLTNGEMV-SVNGADRFPMASTVKVAIAAAFLHQVQ +LGRQSLDRVYSMAADERRKASRIGNMRGGRTASGADLIDLMLTRSDNSAADILLGAVGGT +VAVGEWLHQAGVTGQRVDRSIADLLSAPVGDVRDSSTPEAMATLLAKLRSGDLLDSQHTA +YLFDVMARCRTGAHRLKAMLPGDALIAHKTGTLD-GVSNDVGIISLPNGHELAVAVFEQG +SGG-HGPRDRNIAQLGRMLYDGf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Erythrobacter sp. THAF29 TaxID=2587851 RepID=A0A5P9GNS8_9SPHN +---FERRIAELADGDRGRIGVAAMDLKTGEMI-TVLGDQLFPMASTSKIAVAATYLEMVD +QGKYSLTSEFPLLIPVRSAYSSRAAPVRKGKMPAIDLIEIMITRSSNPATDALLDAVGGP +EKVNQWMRRQGINDFSIDRDIATLVRATWIDPRDAATPRAMVRLLQGLYRGDFLSDQSRR +VLLGAMSRTVTGKRRIPAYMPEVARVSHKTGSLNN-TSSDIGIIEYPDGRAIAVAIYVTG +QG-TRRNREARIASIARALYDGf +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A0H3WME5_ECOLX +------------------------------------------------VLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWLLA--------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium pentaromativorans TaxID=205844 RepID=A0A2W5NKT4_9SPHN +---FGRQLATVAEASRGRIGVAAMDLATGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD +KGKWTLSSEFPLMVPVPSASSAVAPVRAGTYMSARQLIELMITRSNNYATDALLKVVGGP +SAVNAWVRRTGIDEWHIDRDIATLVRAKVVDKRDSATPIAVVELLAGIYNGKWMSKQGRD +VLLGAMSRTVTGKRRIRAGLPAEVVVSHKTGSLNN-TSSDIGIIETPDGHAYAVAIYVTG +QG-TRPNREARIASIARTIYDGy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Alistipes senegalensis TaxID=1288121 RepID=UPI0002ECF424 +-eSLERALRAVTDSVRATVGVAVV-FGDGDTL-AVNGGRCYPMLSVCKFHQALAVLDCLD +RRGLPLTTRIPVRRSDLLSWSPLREACPGGGFTVAELLTYSVAQSDNNVCDVLFRFLGGT +EAVDRYIAGLGIGETVIVADEEMMHRHTDNQYLNRTTPLAAVRLLERFRRGELLSAAYGD +FLLETMFATETGPDKLRGLLPADVAVAHKTGSSDRDADNDIGIVRLPDGRSYSIAVFVMD +SREDDRTNAAVIARISRLVYDY- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. AM37-9 TaxID=2292951 RepID=A0A3A5TCC0_9BACE +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSELKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFCKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRTYSIAVFVKD +SEENSQANSKTIADISRIVYEY- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. AP50 TaxID=1884369 RepID=A0A1H7CEL3_9SPHN +-aKLQAEFARFAALSDGTVGIAVRDLQTGETQ-AFNGDTLFPMASAYKVAVAGRIFSLID +AGDLRLDDKLALDPALASEGIAWMFSRPGASLSVDRLLELMLQKSDNNATDVLVARAGGP +QAITAFVTKLGVTGLRVDSDTAHLLYAFSIEPEDTSTPTAMLDLMTAYEEGRAFSAASTQ +RFFTIMAHCETGKARIKGMLPPGTAVAHKTGSLN-GVGNDVGIVRLPDGRRIAMVVFVMK +DSKGHVSRDRIIAEASRAAYDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Leeuwenhoekiella sp. MAR_2009_132 TaxID=1392489 RepID=UPI00048C3814 +-eNLRNELKAVIINKSATVGVAIHGMREADTL-SINGEKHLPMQSVFKFHLALAILNEVD +NGTLALNTPIEIRKELIENWSPLREKYPNGALELQEILKYTVAWSDNMGCDVLFDLLGGP +AVLQHYLQQLGIDDIAVIHTEMTMQSQFENQFENWTTARASTQLLKRFYEENLLSTESYL +FLLETLKETTTGKSSIKGLLPATTAVAHKTGSSGTAALNDIGIVFLPDNTYFYLSVFVSN +SSEDPETNQQIIAEIAKCTYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8LRJ0_9BACT +---LRAEIAKLLPRARGGVGVAIKHFESGTEI-VVNGDEKYPMASAYKLPILVELFYQRA +AGKLNLDDRIEVAPADLHVGSGSMSQLFDAPLSIRNLINLTMRISDNSAADILLNKV-GA +DNVTARMKSLGLTTIRVDRTTQEMIFEFSKAEKDVASPRDMNLLLEKILRGEIVDRATSD +EIIEILKDCQTGLSRIRGLLPQDAVVAHKTGTIG-GSTNDTGIVYLPRGEHLLITVFTKD +AKATAAERDRGIAEISRYAYDYf +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00077968BE +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSXKN-------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Sphingomonas sp. Leaf33 TaxID=1736215 RepID=A0A0Q4KEQ5_9SPHN +---LTERVAQIAKTDAGKVGAYAIDIDTGAML-AINADNRFPMASAVKLAIAATYLDGVD +KGRWNLATMHMLDEGMRVRSDGITDTLPHAGLSGANLIELSLTVSDNTATDMLLKAVGGP +AAVTRWLQSKGIDGQRVDRTIARLLIAFDADPRDSTTPRAMGELIARLRKGELLKPATTT +FLFDVLARCKTGTKRVKALLPMGTRWAHKTGTLP-GISNDVGVLTLPNGHRVAIALLSYG +IA-DPTTRDARLAEIGRTVFDAf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SX63_9BACT +-sELENRIDSLLNGQKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E1FF925 +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAERNQQI------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=2 Tax=Fischerella TaxID=1190 RepID=A0A1U7GW35_9CYAN +--SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILIAFFQDVD +AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI +EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGNLMAMVSQGNLLNMTSRD +RILDIMRNTVR-NHLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR +PNND-PRAEKLIASISKATYQQf +>[subseq from] Penicillin-binding protein n=1 Tax=Fischerella sp. NIES-3754 TaxID=1752063 RepID=A0A0S3TIV7_9CYAN +--SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILIAFFQDVD +AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI +EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGNLMAMVSQGNLLNMTSRD +RILDIMRNTVR-NHLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR +PNND-PRAEKLIASISKATYQQf +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. 16-62-11 TaxID=1970405 RepID=A0A258XFD4_9SPHN +---IQQQVAAIAAEGRGRIGVAAMDLDGGGQI-FVNGDMPFPMASTAKIAVAATFLEQVE +KGNYRLDQQFPMMLRVAEKGTPSPEARPGSVMTAQSLMELMITRSHNQATDGLIKVVGGF +DNVNRWLTRNGITGQRLDHTMATLVRAKVIDTRTSSTPRAMIALLAAIDRGGVLSPESRA +VLLDTMTRTSTGKTRIRAGVPEGTLVAHKTGTLW-GVTDDVGIVRLPDGRHLAVTFFVTG +PEG-HAAHAKLIARMMRTIYDGy +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides fragilis TaxID=817 RepID=Q57150_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHVYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] Beta-lactamase family protein n=1 Tax=Bacteroides fragilis str. J-143-4 TaxID=1339271 RepID=A0A015WLG6_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLETRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHVYSIAVFVKD +SEADNRENSKIIAEISRIVYEY- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WLS8_9BACT +--SLAPSLLALQKESGGILGVSIQNMETGDTI-SLNGEKPLVMQSSFKFPIALAVFNEIE +NNRLSLEKKVKITKSKLPKWSPLRDQLKENTVSVRELLVFMVSHSDNIACDYLLDIIGGP +STVQNFIHQKGIKNIAIKYSEAEMGKTWEAQYQNWVHPKAMSDLFIKLFHEELLSPEHTK +HLIKLMEETTTGAGRLKGLLPENTIVAHRTGTSGRNAVVDAGVLFLPNGQHAAISVFVTG +SGKETPEIEAVIAKIGRAVWDLy +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=UPI000E1D23CB +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TINNDIHYPMMSVFKFHQALALADCMH +HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] Beta-lactamase family protein n=1 Tax=Bacteroides fragilis str. 3976T8 TaxID=1339314 RepID=A0A016BZA7_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLETRLLIKKSDLKPYSPLREIYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A3E4Q5I8_BACUN +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQNISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISLSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Beta-lactamase class A n=1 Tax=Syntrophus aciditrophicus (strain SB) TaxID=56780 RepID=Q2LTC4_SYNAS +-qRLKSEIHRIAVLTGGTVGLSALHIESGRCF-SLNGMERFPMASAYKIPIAVQLLSRVD +CGDVDLDQFVTIRGSDIHPGSGLTFKKKAASYTVRELLELMLLVSDNTASDALLNLAGGP +EAVTAFMKTLGIRDLDVSRSTLNMLARFYSDIRDTATPDAMTRLVAMVHCGTVLKPESTT +LLLKIMERCKTGQSRIRGLIPPGMATANKTGTIGPGIVNDVALLTLPGDGHLALTIFIKS +SDRSLSYQEQTMAQIARYLYDYy +>[subseq from] Beta-lactamase n=2 Tax=Woeseia oceani TaxID=1548547 RepID=A0A193LK73_9GAMM +-eRLEAEIARIAAGTKGEVGVAMRRIGSDTTI-GYNLRQRFPMASTFKIAVAGATLAMAE +RNEITLQEMVMVDPLLVVPIDKMARHHPGVMLSVLNLINLALTVSDNTATDVLLSKIGGV +DTVNDWLKSIGIKGQRVDSNVAHLLYRFAADPRDSSTPLAMVDLLEKIQTGAALGAEATH +ILLDIMDKATSGKNRLAGRLPENTPVAHKTGTLA-GMANDAGLVELPDGSKFAIAVFIKL +DEGSLAARERIIANISRAAYDYy +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. H115 TaxID=1759073 RepID=A0A0W1CI55_9SPHN +---LNDRLYSLWRAFPGKTGIAVQRIDGEWTL-SQRGDELFPQQSVSKLWVALAVLDAVD +QGRLRMDQPVRIGPEDLTLHQPIAARVRSEGMTVRELIETAITHSDNTANDSLLRTVGGP +GAVRAFISKMDLGAIRFGPGERLLQSNYLANPVDGASPAAIASALTRLARGTLLSPESTD +YLLGVMSRTRSGPKRLKAGLPAGWKFVHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGT +TTSSIPSRMALMQAVSGAVAE-- +>[subseq from] Beta-lactamase n=2 Tax=Gramella sp. KN1008 TaxID=2529298 RepID=A0A4Q9V3F2_9FLAO +-hELKNKFSTIADSSSGNIGVSALHIENGDWV-SLNGDTHFPMQSVYKFPIAMVMLKKID +QGDFSLNDTIFIDKSEYIPHSPIRNMYPDGVLTIEQILEYNVSQSDGTACDVLLRLLGGT +EEVEKYIHELGVTNIAIATTEMIQVANDTIQYQNWATPEAMNKLLVILHKAEYLSKDSHS +LLEKYMSSNNWFDRRIKGLLPEGTEVIHKTGTAGTRATNDVGIIKLPDGNHIAISVFVSD +SYDSQKKREMIIAQVSKAAYDYw +>[subseq from] Beta-lactamase n=1 Tax=Parabacteroides sp. TM07-1AC TaxID=2292363 RepID=A0A3R6RER7_9BACT +-eQLKANIQEIIKDKKARIGVGII-LNGKDTV-TINNEDRYPMMSVFKFHQALAVLNYLQ +QNNLPLDTPIRIEKEDIIEYSPLRDKYPQGNLPINELLKYIIQLSDNIACDVLFKYIGGP +SVADKYIRSLGIQQFSIVITEDDMHQDLSACYLNWSTPLEAARLLEILLTRSLFKDEYQE +FLKNIMIECETGKDRLPQLLKTDAVIGHKTGTSDKGGTNDIGFVLLPNGSRYTVAVFIKD +SNESMETNAKIISSISEVIYKYf +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=2 Tax=Empedobacter brevis TaxID=247 RepID=A0A511NHZ9_9FLAO +-eRLRTEINQIISSKNLTAGISLKNIENKDSL-SINGNQMMPMMSIFKFHIALTVLHEVD +QNKLQLDQKFFIKKRDLLPWSPILDDFPEGNLTLDQLLRYTVSHSDNNGCDILLKIIGGT +KIVQNFIHKQEVKDFVIKVNEQEMQN-WDNLYINTTSANATAKLLEKFYTNKVLKKNSTT +YLYQLMVETSRGSTWMKAGLPANTELAHRTGISDTNAMNDIGIIKLVDGKRIILSIYLKN +ITEERAETEKVMADITKAVWNYy +>[subseq from] Beta-lactamase CARB-3 (Carbenicillinase 3) n=1 Tax=Photobacterium damselae subsp. damselae CIP 102761 TaxID=675817 RepID=D0Z431_PHODD +--------------------------------------------------------ADSD +KDKSVLTYPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ +QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ +SSASMDERNKAIATIGKQVFTYf +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. 17-62-19 TaxID=1970406 RepID=A0A259DTC8_9SPHN +---IQQQVAAIAAEGRGRIGVAAMDLDGGGQI-FVNGDMPFPMASTAKIAVAATFLEQVE +KGNYRLDQQFPMMLRVAEKGTPSPEARPGSVMTAQSLMELMITRSHNQATDGLIKVVGGF +DNVNRWLTRNGITGQRLDHTMATLVRAKVIDTRTSSTPRAMIALLAAIDRGGVLSPESRA +VLLDTMTRTSTGKTRIRAGVPEGTLVAHKTGTLW-GVTDDVGIVRLPDGRHLAVTFFVTG +PEG-HAAHAKLIARMMRTIYDGy +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPLOWO2_02_FULL_61_11 TaxID=1797950 RepID=A0A1F9VTH8_9BACT +--AMVESLDKLSRSYRGRVGIYIRDLETGKTW-AYNAEKLFPSASLIKVPIMAAVFEKIK +LGEFTLDTQIKLTRPSRVGGSGSLKWVREGTLSVMEIVYKMITESDNTATKMLIDQV-GM +PYLSEAFKKLGLEHTNITPEGMSLSS-YRVKRENYTTPREMASLLERIYAGELVNRESSE +FMLDVLKHTKS-RSRLRKGLPLGWEIGHKTGLLRK-ACHDVGIVFSPRGD-YVIAVLTSE +AP-NYTTAKNFISKVAKLTYRYy +>[subseq from] Beta-lactamase n=1 Tax=Dyella japonica A8 TaxID=1217721 RepID=A0A075K399_9GAMM +-dALQHSLDALAQRAPATLGIAVVDLSTGASA-RVNAEYAFPMMSVFKAPVAAVVLSRVD +EGTLSLQEPVEITRGQVQGGSPSIGAHFRGEFTVEQLLKAAVSESDNTAVNALIRTVGGP +AVVTGYLHAHGIDGMRVDLDEAGISRAFLDDPRNRTTPDAAVAFLHKLVDRELLSPASTQ +RLLALMEAQTI-PNRLRAGVPSGLRFADKTGTSGTAAYNDIGIITWPDGRRVLVAAFLLD +SSMTDKERGQLFADIARQVT--- +>[subseq from] Beta-lactamase class A n=1 Tax=Bosea sp. BK604 TaxID=2512180 RepID=A0A4R3EDT8_9BRAD +--KLDAEIPVIEQQTGGKLGVALIDLKDRKSW-SHRGKEPFPLQSVFKLPLGIAVLQAVE +AGKFKLDQPITVTRKDLSLHSPLAKSFKGESYPLRDLLTRATGDSDNTAADLLLRLVGGP +QVVTKMLRDGGVEGISVDRYERVLQPSVLDDKRDSATPEASIAFLDGLAAGNWLREPAHA +LIEKITVESKSGPQRVRAGLPEGARFAHKTGLGPNHATNDIGIVTLPNGRRFAIAVYLKG +ATVDEKAREAAHAAVAKAAVA-- +>[subseq from] serine hydrolase n=1 Tax=Tolypothrix sp. PCC 7910 TaxID=2099387 RepID=UPI0014278DEF +--SLKTAVQNLAAANNLTPGVLLVDLDTGSYV-DINSAASFPAASTIKVPILVAFFQDVD +AGKIRLDEMLTMQQSMIAGGSGNMQYKPAGTYSALEVATKMITISDNTATNMLIARLGGI +EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVNMRSRD +RLLDIMRQTER-DNLLPSGLGTGATIAHKTGDIGT-MLADAGLVDIPTGKRYIAAVMVQR +PNND-PRAEKLISGISRAAYQQf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A6A0IJK0_9BACT +---LADAVAAEARRCGGHVGVHALHLPSGRSF-SLEAGTPFPMASVYKLPIALAVLGAVD +AGQLTLDEALPVEEGDFRRGVPARERFRAGVLRVEEALRLMVRESDNTATDLLLRRIGGP +AAVQARLGELGLAGVRVDRTEIRMAAAFLTDPRDTATPAGMTALLARLVAGDLLSGPSTS +RLLGWMRDSPTGARRIRAGAPAGSVVQDKTGTHWS-GANDVGVVDLPEGGRLLLAVFVKG +SDLPVPEQEDAIAGIARLLA--- +>[subseq from] Beta-lactamase n=2 Tax=Dyella sp. DHOA06 TaxID=1920169 RepID=A0A3S0RGC4_9GAMM +--TLQAQIDALAKRAPGAFGIAVLDLQSGDTW-QVNADKAYPMMSVFKAPVAATVLSRIE +HGQNTMDQTVTVTRADL-GYGPIRDQFKGEQFTVRQLLAAAVSKSDNSAVNALVRLVGGP +TIVTAYLREHGITGMRVDRDEAGIGRRFMADPGNRSTPVAAAAFLQKLWHNELLSPASSK +YLLDLMYAQTL-THRLRGGLPPGVKLADKSGTSDSAAYNDIGIMVWPDGHAVIVAAFMSG +SNAPPKQRDAMYAELARDVAK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. ZX TaxID=2606412 RepID=A0A5D9C6Y1_9SPHN +-qRLDARLEAFTQRKDIRVGIAAVHLESGAAL-SVNGDEAFPMASAYKLAAVLTLLHQVE +QGRFTMDQMIPVDDALRVQSGGISTSMPHPGLSVANLIDLTITRSDNTAADMVTQMVGGP +AAITAWLRSVGIEGQRVDRDVAGLIFAFIADPRDSSTPDAMVALLAKLQRGQLVDAEHTA +WLLDVMAHTVTGAKRVKGLLPPRTVFAHKTGTLV-GICADVGILTLPGGGHVAVAIFVKS +HD-DGAKAEAIIAEAGRTIYD-- +>[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. RIFCSPHIGHO2_01_FULL_69_31 TaxID=1801944 RepID=A0A1G2WBK6_9CAUL +-------------ARPAALGVGLSNLESGQAY-TFNGDRRFPMQSVFKLPLAAAVLAEAD +AGRMMLAEPFVLTEEQLSPVSPIAAAWPGRRYTAQALFEAMVIDSDNTAADVLMKRIGGP +GAVTAWLTARRVPEVRVDRYERELQPRYMSDPRDTATPRGMLEFLQMLDRQELVSPASTK +RLIELMGRTRRGGERIRAGLPRDAFLAHRPGTSGSTAHNDVGIFTLADRRSYALAVFLSG +STLDEGGRDRIIAEVTRAAVR-- +>[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5205 TaxID=2019671 RepID=A0A2N6MLV8_9CYAN +--SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD +AGKIRLDETLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI +EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGNLMAMVSQGNLLNMTSRD +RILDIMRNTVR-NHLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVAVMVQR +PNND-PRAEKLIGSISKATYQQf +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. M8 TaxID=1925550 RepID=A0A1Q8IIN4_9NOCA +------------------------------------------------------------ +---------------------------------------------DNTAGNLLLRRLGGP +TAVTAFARSLGDTVTTLDRWEPELNSAEPGDVRDTSTASGLARGYRELLLGSGLPAAGQQ +TLTGWMRASVTSGQRIRAGLPAGWTAADKSGAGRYGTVNDAGVLWSPDGSPLVLVLLSDS +VTPDAAHDNAAIAEATAVIVE-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=UPI00125FF6A9 +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP +DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIANISRIVYEY- +>[subseq from] Beta-lactamase family protein n=2 Tax=Bacteroides fragilis TaxID=817 RepID=A0A017NG10_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLETRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHVYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=Croceicoccus naphthovorans TaxID=1348774 RepID=A0A0G3XMN1_9SPHN +---LRQQLFAVARADKGRIGVAALDLSSGQTV-SILGDQAFPMASTSKIAIAATFLAGVD +AGKYQLDDKYPLMIPVASRSTAVAPVKPGMSLTARSLIELMITRSDNAATDAMLKAVGGP +AEVTKWMRSKGFNRFRIDRDIATLVRATGADQRDSAPPMEMVQLIAGLYKGQWLSGPSTD +VVIGAMTRTVTGSRRIKAGLPSGTSFGHKTGTLNN-TASDVGFVEMPDGRVVALAIYVTG +QG-GRPQRDARIAEITRTLYAGf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Alistipes provencensis TaxID=1816676 RepID=UPI0007ED4F40 +-eSLERAVRAVTDSVRATVGVAVV-FGDGDTL-VVNNACRYPTMSVYKFHQALALLDDLD +RRGLPLTTRIPVRRSDLLPWSPLREACPEGGFTAAELLAYSVAQSDNNVCDVLFRFLGGP +EAVSRYIAGLGIGETVIVADEETMHRRTDNQYLNWTTPLAAVRLLELFRRGELLSAASGD +FLLKTMFATATGPDKLRGLLPPGVAVAHKTGSAFRDADNDIGIVRLPDGRSYSIAVFVMD +SREDDRTNAAVIARISRLVYDY- +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides TaxID=816 RepID=A0A414IMN9_BACUN +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYICRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Carbepenem-hydrolyzing beta-lactamase KPC n=1 Tax=Erythrobacter sp. THAF29 TaxID=2587851 RepID=A0A5P9GW22_9SPHN +---LASKLRIIEAAAGGTLGAEIHDTGTGMGF-GLNRHMRFGHCSSFKMSLAAMALARDA +SGLVSKDRQVTWTEDDLMAVSPFTTERLAEGATISELAEATQKFSDNAAANILLREFGGP +QELTGFWRFLGDTVSRLDRIEPLVNNVPEGEIQDTTTPFAMARTVARITQGQVLPDTHRG +LLTQWMVDTRTGLRRVRSGLPEGWLAGDKTGTSLDSLYVDIGFVEPPNRAPLAFAAYYRA +RGTHEPAAEQVLARVGGVIADY- +>[subseq from] Uncharacterized protein n=2 Tax=Bacteroides TaxID=816 RepID=A0A0J9FBX5_9BACE +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +ETVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRIYSIAVFVKD +SEENSQANSKIIADISRIVYEY- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter aquimaris TaxID=255984 RepID=UPI00135ED51F +-nALEQTIAELADGSKGRIGVAAVDLSTGKTV-SVLGDQLFPMASTSKIAVAATFLEGVE +KGKWSLTSEFPLLLPRRSASSPRAPVYEGQYMKAIDLIEIMITRSSNPATDALLRVVGGP +EAVNDWMRRQGIDEFSIDRDIATLVRAQHIDTRDAATPNAILELLSGLYQGKYLSAESRR +VLLGAMSRTRTGKRRIPALMPASVKVSHKTGSLNN-TSSDVGILETPDGRAVAVAIYVTG +QG-SRLNREAKIAQIARALHDGy +>[subseq from] Beta-lactamase n=5 Tax=Akkermansia muciniphila TaxID=239935 RepID=B2UM78_AKKM8 +-----SAVRELAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD +QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP +QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQS +VLWNIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD +SKDSESACDRVIASMARWLCL-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium nakagawai TaxID=1241982 RepID=A0A448LKC3_9FLAO +-sELKKAIETILAHKKADVGVSIVTAGKKEVI-QINGNKPLPMLSTFKFPVALAVLHKVE +KGELSLQQKIYIKKEELLEYSPFKDKYPDGNLSLEDCIQWMVVYSDNNLTDILLRLIGGP +DYVQQFINS---KNIVIKNDEEGMHKDWDSQFINTITPNEATWLLEQFYTGKILNKEHTK +WLYTAMLNNATGAKRLKGKLPKDVKVAHRTGTSFTGAVNDYGIIELSDKKRIYIAVLVHD +TYETFENSEAIIADIAKAAYNHy +>[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI0011AFC0FB +-----SAVRELAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD +QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP +QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQS +VLWNIMAGCSTGPERLKGQLPQDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD +SKDSESACDRVIASMARWLCL-- +>[subseq from] Uncharacterized protein n=1 Tax=Bosea sp. Tri-39 TaxID=1867714 RepID=A0A4Q1U331_9BRAD +--RLDSGIRTIEQGTKGRLGVGLIDLKDRKSW-SHRGSEPFPLQSVFKLPLAIGVLQAVE +AGKLKLDQTITVTRNDLSLHSPLAKAFKGERYPLRELLTRSTAESDNTAADLLLRLIGGP +QALTAILKDGGVSGISVDRYERVFQPATLTDKRDAASPEASIAFLEGLAKGTWLRDPAHA +ALLDIMLEAKTGPNRIKAGLPKGARFAHKTGLGPNHATNDIGIVTLPDGRRFAIAVYLAG +AQVGEIDREAAHAAVARLAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=E0WMX8_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLKTRLLIKKSDLKPYSPLREIYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caecimuris TaxID=1796613 RepID=A0A3A9B5K0_9BACE +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTA-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGYNDIGFVLLPDGRTYSIAVFVKD +SKENSQVNSKTIADISRIVYEY- +>[subseq from] Serine hydrolase n=1 Tax=Altererythrobacter sp. FM1 TaxID=2484537 RepID=A0A3N2QN10_9SPHN +--ALERLVGQIADGSQGRIGVAAVDLVTGQQV-SILGDQRFPMASTSKIAIAATFMEGVE +QGRWSLSSEFPLMVPVRSASSAVAPVRPGKYFKAVDLIEMMLTRSSNQATDALLKVVGGP +RAVNKWVRAQGIQEFQIDRDIATLVRAKQIDTRDSATPKAMVKLLTGLYQGKYLSEASRR +VILGAMERCRTGSRRIKALLPGTAIVAHKTGSLNN-TSSDIGVIKAPNGHAIALAVYVTG +QG-SRPAREAKIASIARTLYDGy +>[subseq from] Beta-lactamase n=2 Tax=Akkermansia muciniphila TaxID=239935 RepID=A0A2N8IHY6_9BACT +-----SAVRELAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD +QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP +QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILARGTQN +FLWGIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD +SKDSESACDRVIASMARWLCMEw +>[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=A0A3R5UIP5_9BACT +-----SAVRELAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD +QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP +QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILARGTQN +FLWGIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD +SKDSESACDRVIASMARWLCMEw +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium HG15A2 TaxID=1930276 RepID=A0A517MTN7_9BACT +--ALAAQLQPLIDAHQGVVGVMVKDLKTGVEF-RHRVDEPMPTASLIKFPIMIATYQAIE +RGDLKLDRKLTLQEEDKVPGSGILTEHFEAGMPLKNAIHLMMAVSDNTATNLVIDQL-GL +EATNDLMESLGCPNTKLHAKVFRRDTRSQRYGLGSTTAAEMVKLLESLQNGELVSQEASK +LMREQMSAIGS-QAKFPRLLPDGVKLIHKTGSVS-AARTDAGIILSPHG-PIALCVLTEK +NKADDNAGEMLCSHIAKEVYDLf +>[subseq from] Beta-lactamase n=1 Tax=Croceibacterium mercuriale TaxID=1572751 RepID=A0A0B2BXX1_9SPHN +---LQQQIARLADGGQGRIGLFAVDLATGEEI-AVLGDQRFPMASTSKIAIAATFMEGVE +RGRWSLSSEFPLMVPVASRSTAVAPVRAGEHLSARQLIELMITRSSNPATDALLKAVGGP +AAVNDWVRRNGISEFNLSRDIATLVRATSIDTRDSATPRAMVQLLSGLHQGRFLSDSSRR +VILGAMERCRTGTRRIRALMPAGVTVSHKTGTLNN-TASDIGFIHAPDGRTIAVAIYVTG +QG-GRPGRDAKIANLARAIYDGy +>[subseq from] Beta-lactamase class A VEB n=1 Tax=Flavobacterium sp. 5 TaxID=2035199 RepID=A0A2N0HAA9_9FLAO +---LKSKIENILKGKKATVGVSIVANHYKDTL-NINGNEHLPMQSVYKFPIALAVLSEID +KKKFTLHQKIKITKNELPYWSPIRDEYPNGVLTISDILRYTVSQSDNNGCDILLRFIGGT +KVVEDYLSENKLTNISIKTTEEEMHQEWDVQYQNWATPIALNTLLIKSYDTQILSKENYK +FLWKAMTETSTGLKRLRGQLPKKTIVAHKTGLSGTAATNDIGVIVLPNGEPIFITVLVSD +STENAETNEKIISDIAKATWDYy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=UPI001230258A +--SLETQLKEAIKDKKAEIGIAVI-TDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA +KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP +DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD +FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEESFAENSKIIADISRIVYEY- +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=UPI000EFFC4E3 +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLNSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5318 TaxID=2019666 RepID=A0A2N6LIE3_9CYAN +--SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD +AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI +EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGNLMAMVSQGNLLNMTSRD +RILDIMRNTVR-NHLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVAVMVQR +PNND-PRAEKLIGSISKATYQQf +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter sp. BO-6 TaxID=2604537 RepID=UPI0013E13BE9 +-tSLERRIAQLADGSNGRIGVAAIDLATGEEI-GVLADQYFPMASTSKVAVAATFLEMVE +QGKYSLTSEFPLLIPVPSAFSSAAAPVRQGEMPAHQLIEIMIARSSNPATDALLAAVGGP +KKVNDWMRRHGFKEFSINRDIATLVRAQHIDKRDAATPREMLRFLAGLYQGKFLSGSSRR +VLLDAMSKTRTGKRRIPALMPAEVEVSHKTGSLNN-TSSDIGIIEGPDGRAIAVAIYVTG +QG-SRAAREDRIAAIARALYDGf +>[subseq from] Beta-lactamase class A n=2 Tax=Luteibacter sp. OK325 TaxID=2135670 RepID=A0A2T5LGP2_9GAMM +------------------------------------------MCSTFKLLAVAAVLNRVD +KGSECLDRRIYYGRDVLLSHAPVTSLHADGEMTVGQLCDAAITVSDNTAGNLLLQAIGGP +DGFNVTMRAFGDTATRLDRTEPKLNIA--SGVLDTTTPEAMGQVAGRLLSGGLLMPTSVA +KLSDWLRAATPGLTMLRAGFPAEADAGDKAGRGTGGQNNDIAIVWKQGKKPLLVAAYYVN +SDMDDGQRNAVLAEVGRVVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. EPR-279 TaxID=1813678 RepID=UPI0007BBD5DD +---------------------------------------------------VGAVLAAVD +AGALQLSDTRTITAADKVPESAVD-WEPGSVVTIADLASAALTESDNTSGNLLIREAGGT +AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTAASRE +QLLAWMADTQTSDARFRAGIPDGWTSADKTGTGSYGVSNDAGLLLGPDGQRILVVVLSAT +TSEDSPAMNSLVSDATRQVVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Rudaea cellulosilytica TaxID=540746 RepID=UPI0003A8C511 +--ALQSRLAALAQRAPGTLGVAVLDLRSGTSW-RINAGRGYPMMSVFKAPLGAAVLERVD +RGKLSLDREITLTSVDLRPPGPIGGEIQAGHFSVRRLLDAAVSESDNTAADALVKLVGGP +TAVTTFLRAHGIEGIRVDRDERTLAHAFLTDPRDTSTPEAAVAFLCKLWRGELVSRTSTT +LMLEMMTHSPTVPNRLKGGVPAGAHLAHKSGTSITAAHNDIGILSWADGRTVIVAAFLTA +SPASEQERDAIFATLTRDV---- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. CBA7301 TaxID=2715212 RepID=UPI001435BFAD +---LETQLKEAIKDKKAEIGIAVI-IDGKDTV-TVNNDTHYPLMSVFKFHQALALADYMA +KHKQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDVLFNYQGGP +DAVDKYIHSLGIKDCAIVGTETAMHEDLDLCYQNWSTPLAAAELLEIFRREPLFAKEYKD +FIWQTMVECQTGQDRLVALLDKGVIVGHKTGTGDQIGCNDIGFVLLPDGHTYSIAVFVKD +SEESFAENSKIIADISRIVYEY- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI00035E7BEB +-dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD +DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT +KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA +HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE +SRAGKDERAATIAAA-------- +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides fragilis TaxID=817 RepID=Q45115_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLKTRLLIKKSDLKPYSPLREIYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDRHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI000B8E3111 +-----SAVRELAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD +QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP +QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILARGTQN +FLWGIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD +SKDSESACDQVIASMARWLCL-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI0007D945B0 +-----KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNTP +--TSELNKKIVISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI +KEFQQALIHRGDHISNPQRPEPDLNLYDPQSTDDTTTPKRAATTFNHLLQSENMSKANLE +LLKHTMIHNETGGTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK +SDKDAKPDDKVIQTAAETAIK-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium BRH_c42 TaxID=1734407 RepID=A0A117S421_9SPHN +-tSLERRIAQLADGTRGRIGVAAIDLSTGRQI-AVLGDQLFPMASTSKIAVAATYMEMVE +QGKYSLTSEFPLLVAVGSASSAVAPVRKGEHMAAIDLIELMITRSSNPATDALLAAVGGP +AKVNDWVRRQGIREFSINRDIATLVRATHIDRRDAATPRAMVELLRGLYQGKYLSAESRR +VILGAMSRTSTGKRRIPAQIPLGAQVSHKTGSLNN-TSSDVGIIETPDGRAFALAIYVTG +QGAR-AAREERIAAIARALYDGf +>[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI000C9A686A +-----SSVRKLAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD +QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP +QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILARGTQN +FLWGIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD +SKDSESACDRVIASMARWLCMEw +>[subseq from] Beta-lactamase n=3 Tax=Akkermansia muciniphila TaxID=239935 RepID=A0A2N8IPJ1_9BACT +-----SAVRELAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD +QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP +QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQS +VLWNIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD +SKDSESACDRVIASMARWLCL-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis sp. KK2 TaxID=1855727 RepID=UPI00097E6754 +---LDNRLFEIWRAFPGKTGIAVQRIDGEWAL-AQRGNELFPQQSVSKLWVTLAVLDAVD +NGRLTMDQKVRIGPEDLTLHQPIAARVQSQGMSVRELIETAITQSDNTANDSLLRTVGGP +DAVRRFIDKKDLGAIRFGPGERLLQSAYRADPPDGASPAAIAKALSRLARGTLLSPESTQ +YLLGVMSRTKSGPQRLKAGLPAGWTFLHKTGTGQRGGYNDIGIATAPDGTRYAIVVMMAE +ASSPVPARMATMQSVSRAVAE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SPI0_9BACT +-sELKNRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYICRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. NAP1 TaxID=237727 RepID=A3WF43_9SPHN +--SFEQRIAELADGDRGRIGVAALDLATGESV-AVLGDQLFPMASTSKIAVAATYLEMVE +QNKYSLTSEFPLLIPIRSASSPAAPVRRGNYMPAIDLIEIMITRSSNPATDALLAAVGGP +EKVNDWMRRQGITDFSIDRDIATLVRANWIDPRDAATPRAMVRLLQGLYRGDFLSDQSRQ +VLLGAMSRTVTGRRRIPANMPDEAVVSHKTGSLNN-TSSDIGIIESPDGRAIAVAIYVTG +QG-TRRNREARIASIARALYDGf +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingopyxis sp. PAMC25046 TaxID=2565556 RepID=A0A4P7RW00_9SPHN +---LDDRIFQLWRAFPGKTGIAVQRIDGEWSL-SQRGDELFPQQSVSKLWVALTVLDAVD +QGRLTLDQRVRIGPEDLTLHQPLAARVRSEGMSVRDLIETAITHSDNTANDSLLRTVGGP +DAVRAFIDKKDLGAIRFGPGERLLQAAYLANPPDGASPEAIASALTRLARGTLLSPDSTE +YLLGVMSRTRSGPRRLKAGLPAGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGD +TSASVPARMALMQAVSGAVADY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. LC363 TaxID=1120705 RepID=A0A095B9Q1_9SPHN +---LDDRIFELWRAFPGKTGIAVQRIDGEWSL-SQRGDELFPQQSVSKLWVALTVLDAVD +QGRLTLDQRVRIGPEDLTLHQPLAARVRSEGMSVRDLIETAITHSDNTANDSLLRTVGGP +DAVRAFIDKKDLGAIRFGPGERLLQAAYLANPPDGASPEAIASALTRLARGTLLSPDSTE +YLLGVMSRTRSGPRRLKAGLPAGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGD +TSASVPARMALMQAVSGAVADY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A1W6AL31_PSEAI +-----------------------------------------------KVMAAAAVLKXSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGXP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYG------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Porphyrobacter tepidarius TaxID=60454 RepID=UPI000A3BC79A +--SFSQRIAELADPSQGRIGVAAVDLATGEQI-MVLGDQLFPMASTSKVAIAATFLEMVD +KGRYSLTSEFPLLLPERSASSPKAPVRPGQYMPAIDLIEIMITRSSNPATDALLAAVGGP +AAVNDWVRRQGIENFSINRDIATLVRAYHIDKRDAATPRAMTQLLAGLYRGDFLSDESRR +VLLGAMSRTVTGKRRIPAHIPLEARVSHKTGSLSN-TSSDIGIIECPDGRAIAVAIYVTG +QG-SKLAREERIAAIARALYDGf +>[subseq from] Serine hydrolase n=2 Tax=Phenylobacterium sp. LX32 TaxID=2170551 RepID=A0A328AKA6_9CAUL +--ALQEKIEQLAERYREPVGIAITDVSARWTA-QVAGDEVFPQQSVSKLWVALAVMHAVD +RGQLRLDQPVTLTKEDRSVYQPITAKIRGPNTSVYELLKYQLTESDNAANDKLIAEVGGG +EAVSRVMAEKGLEGLGRGETERDLQTAYLANPGDGAKPAAITNALAALHRGELLSPQSTE +AMLDLMAQCRTGSSRLRAGLPSGWSIAHKTGTGPSVGINDVGLITAPDGRTYAVAVMLRQ +TRHPVGARQALMQAVARAVVDYw +>[subseq from] class A beta-lactamase n=1 Tax=Sphingobium sp. CAP-1 TaxID=2676077 RepID=UPI0012BB326F +--KLLAEFARFATLSDGTVGIAVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRIFALVD +AGDLRLDDQLALDPALASEGIAWMFSRPGATLSVDRLLELMLQKSDNNATDVLVARAGGP +QAITAFVTRLGVTGLRVDSDTAHLLYTFATEPEDTSTPTAMLDLMTAYEEGRALSPASTE +RFFTIMAHCETGKARIVGMLPPGTAVAHKTGSLN-GVGNDVGIVRLPDGRRFAVVVFVMK +DSKGHVSRDRIIAEAARAAYDYf +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SDB7_9BACT +-sELENRIDSLLNCKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] serine hydrolase n=1 Tax=Novosphingobium lentum TaxID=145287 RepID=UPI000834391F +---VQQQLAGIVAQSRGRIGVAAVDLDGGGQV-MINGDQPFPMASTAKVAIAATFLSQVE +AGRLRLDQNLPMMIRERGPRSAVAPVRQGPIYAAQSLMELSITHSNNEATDGLLSAVGGP +QVVNAWLTRAGITGQHLDHTMATLVRARVIDVRTASTPRAMVALLGAIDRGNALSPQSRA +ILLDTMTRTVTGSKRMRAGLPEGVVFAHKTGTLS-GVTDDVGIIRLPDGRHLAVAIFVTG +PEG-HSAHGAMIAQITRTLYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Streptococcus pneumoniae TaxID=1313 RepID=UPI0013DCE502 +------------------------------------------------------------ +----------------------------TDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRFVVIYTTG +SQATMDERNRQIAEIGASLI--- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus sp. 47.1 TaxID=1929484 RepID=UPI0008A51EFE +-----KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNTP +--TSELNKKIVISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI +KEFQQALIHRGDHISNPQRLEPDLNLYDPQSTDDTTTPKRAATTFNHLLQSENMSKANLE +LLKHTMIHNETGGTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK +SDKDAKPDDKVIQTAAETAIK-- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. PC22D TaxID=1962403 RepID=A0A2A8I184_9SPHN +--AFEARIASLAEASQGRIGVAAMDLSTGRVI-DVLGDQRFPMASTSKIAIAATFLEGVE +KGRWSLTSEFPMMMPVRSESSAVAPVRAGEYYTAGKLIELMLTRSNNYATDALLRVVGGP +AAVNAWVHRAGITDWQIDRDIATLVRAEVIDSRDSATPMAMVQLLAGLHEGKWLSDSSRQ +LILDTMGRCLTGRRRIVANLPTEARVAHKTGSLFN-TSSDVGIIETPDGRAFAVAIYVTG +QG-TRLKREARIASIARALYDGy +>[subseq from] Beta-lactamase class A n=3 Tax=Nitrospirillum amazonense TaxID=28077 RepID=A0A560J239_9PROT +--ALQARLDRLAHDFPGQAGIAVRDGLTGAEV-GVKARGRFPEQSVFKLTVAIALLDLVD +HGRMDLAQKVTLYPKDRSVWQPLAKNITPAGTTLDDLMARMVADSDNVAADTVLRLIGGP +AVVQAALTARGLDGIRVDRDERHLQSAYLSDPRDTAQPATMALLLDRLDKGALLSPASTR +RLLDILDHTTTQPNRLKAGLAAGWTVAHKPGAGPTLANNDVGLMTAPDGHRYAVAVYVAS +VQGPRERADAFIASVARAVVESw +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacterium sp. 1.A.5 TaxID=2044604 RepID=UPI000C0BFA74 +---LKKKIEQIISQKNSVVGVSIIGNNGRDTL-SILGDKKFPMQSVFKFHIALAVLDLVD +KGKLSLDQTVKVGKKDLMTWSPLRDENPNGGFTIEKLIQYAVSHSDNTACDVLIKLVGST +KDVEKYFKKNNIQDIQITYNERDMQAKWENMFQNWTTPKAASKTMMLFYEKEPISKNSYF +VFWRTNFETTTGEKRIKGKLPVGTHVAHKTGWSGTAAVNDIGIVVLPNDQHFYISVFITE +SKENFDSNEELIADIAKAAYDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A0M4FFL9_KLEPN +---------------------------------------RFAMCSTKKVKAAAAVLMKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGD-------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. AM16-24 TaxID=2292002 RepID=A0A414ZCQ7_9BACE +-kELEQPIGQVLKDKKATVGVAVLVNDTIVA--LHNNQIHFPLFSVFKFHVALAVLDKMD +KGHVSLDSIMEIKAAQMLPYSPLRQKFPDRDISLGELLKYSISLSDNNACDVLIDYAGGI +DKVNSYIKSLGLKDFNLAANEELMHRDVATQYQNWSTPEAVVRLLNIADKQTLFAAEYKD +FLWQILKETSTGTDKLKGELPPDVIVGHKTGSSDKTADNDAGFIILPDGRKYYITVLVME +SQETDRENAAIIARISKIVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Halomonas axialensis TaxID=115555 RepID=A0A455V9W0_9GAMM +-----------------------------------------------------------D +EGLLAPDTEVSFDESALVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLILEALGGP +EAITAFARRLDDSVTRLDRFETELNEATPGDERDTTTPNAMLATLETLVLGDVLTPESRQ +QLQDWMKGNAVADGLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQAPTVAVFYPHR +NRRSAQRSHCV------------ +>[subseq from] class A beta-lactamase n=1 Tax=Myxococcus sp. AM301 TaxID=2709664 RepID=UPI0013D75B33 +-gELGERLARAVAPAEGPVGVAVVDDADGAAV-VLGGGRRFPMQSVFKLPLAMAVLDAVD +RGELRLEQRVRVEPSDFVSHSPLRDAHPDGVLTLGELLRGAASGSDGTAADVLLGLVGGP +VAVTRYLRSVKVEGVEVAVTEKEMGRDPKAQYRNWATPEGAAALLLAVEAGRGMSADGRR +HLLRLLTETPTGPNRIRGRLPAGTPVAHKTGTSRTAATNDIGLVTLPDGRRLVVAVFVSE +SPADDATRERVIADVAREAFDFw +>[subseq from] Uncharacterized protein n=1 Tax=Bosea sp. Tri-44 TaxID=1972137 RepID=A0A4Q1V5W8_9BRAD +--RLDSGIKTIEQSTKGRLGIGLIDLKDRKSW-SYRGAEPFPLQSVFKLPLAIGVLQAVE +AGKLKLDQKITVTRNDLSLHSPLAKAFKGERYPLRELLARSTGESDNTAADLLLRLIGGP +QALTALLRDGGVSGISVDRYERVFQPATLTDKRDAASPDASIAFLEGLAKGTWLRDSTHA +ALLDIMLEAKTGPNRIKAGLPTGARFAHKTGLGPNHATNDIGIVSLPDGRRFAIAVYLAG +AQVGEKEREAAHAAVAQLAVE-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacterium sp. G1-14 TaxID=2003121 RepID=UPI000B490DA1 +-nSLRKELHQIIATKNATVGISMKGIETKDTL-SINGHLNAPLMSVFKFHIALATLNLVD +QGKLSLSQKFFIKKEDLHAWSPIRDEFPNGNLTLDQLLRYTVSHSDNNGCDILLDLIGGP +ETVQKFINKQGIKDFTIKVNEQEMR-IWENLYSNTTTPLASTELLEKFYARQVLKKNSTK +YLYQLMVECSRGLTWMKAGLPERTELAHRTGISDRAAMNDVGIFKLPNVNHVVLSVYLKD +ITEEREVTEKIIADITKAIWNYy +>[subseq from] Class A beta-lactamase, subclass A2 n=3 Tax=Bacteroides TaxID=816 RepID=A0A414E6J5_BACOV +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANNKIIADISRIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=Francisella sp. FSC1006 TaxID=1547445 RepID=A0A097EMU0_9GAMM +--SLDDSFKDLENKYNGKLGIYSTD---KSSI-NYNENYYFPICSVFKFLLVGAILEKDM +HNKGFLDKKITITQKDISTYAPVTGKNISKDLTISQLCFAAI-LSDNPAANILVKELGGI +DKLNKFIKKLGDNDTNIKNIEPKINHTKPDSTINKTTPKAITNDIYKIAFGNILDEKHKE +IFIKYLQDNNTGVNRIAYNTPKNWIVGDKTGTCGYGATNDIAIIWPQNAEPFALGMMYTD +PTKKAPSSEKIIQQATKLVI--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=V5W4S6_ECOLX +------------------------------------------------------------ +-------------------------------MFLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAK------ +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI0009BF3A38 +-----KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNTP +--TSELNKKIVISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI +KEFQQALIHRGDHISNPQRPEPDLNLYDPQSTDDTTTPKRAATTFNHLLQSENMSKANLE +LLKHTMIHNETGGTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK +SDKDAKPDDKVIQTAAETAIK-- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. Alg231-14 TaxID=1922225 RepID=UPI000D553C37 +--SFEQRIAELADGDDGRIGVAAMDLATGEQI-MVLGDQLFPMASTSKIAVAATYLEMVE +QGRYSLTSEFPLLIRVRSPSSPAAPVREGEYMPAIDLIEIMITRSSNPATDALLAAVGGP +QAVNAWMRRQGINDFSIDRDIATLVRANWIDPRDAATPRAMVRLLQGLYRGDFLSDQSRQ +ILLGSMSRTTTGRRRIVANMPSEARVSHKTGSLNN-TSSDIGIIESPDGRAIAVAIYVTG +QG-SRLARERRIAAIARGLYDGf +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. AAP83 TaxID=1523425 RepID=A0A0N1C5A7_9SPHN +---IQQQIAAIAAEGRGRIGVAAMDLDGGGQI-MVNGDMPFPMASTAKIAVAATFLEQVE +KGAHRLDQEFPMMLPVRETISPVAPLRAGTVLTAQSLMELMITRSHNEATDGLINAVGGI +ENINYWLTRNGIAGQRLDHTMATLVRARVIDTRTSSTPRAMIALLAAIDRGGVLSPESRA +VLLDTMTRTSTGKTRIRAGLPEGTLVAHKTGTLS-GVTDDVGIVRLPDGRHLAVAFFVTG +PEG-HAVHAKLIARMMRVIYDGy +>[subseq from] TLL2115 PROTEIN n=1 Tax=Synechococcus elongatus TaxID=32046 RepID=UPI000181CD26 +--NLQQQIQQLVSRQNLTAGLYFFNLDSGASL-NVGGDQVFPAASTIKFPILVAFFKAVD +EGRVTLQERLTMRPDLIAPEAGTLQQKPNSQYAALEVAELMITISDNTATNMIIDRLGGA +AELNQQFQEWGLENTVINNPLPDMKGT------NTTSPRDLATLMLKIGQGEILSPRSRD +RLLDIMRRTVT-NTLLPAGLGKGATIAHKTGDIGI-VVGDAGMVDMPNGQRYVAAMMVKR +PYND-PRGSELIRQVSRMVYQAf +>[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter sp. LM 6 TaxID=1896196 RepID=A0A1D7NHC6_9SPHN +--SFEQRIADLANPAQGRIGVAAIDLATGEEI-AVLGDQLFPMASTSKVAVAATYLEMVE +KGRFSLTSEFPLMMPVASAKFSTAKAPVRAGMPAIDLIEIMITRSSNPATDALLAAVGGP +GVVNDWMRRQGIKEFSINRDIATLVRAYHIDKRDAATPRAMVRLLAGLYKGEFLSEQSRQ +VLLGAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDVGIIECPDGRTIAVAIYVTG +QG-SKQAREERIAAIARALYDGf +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides uniformis TaxID=820 RepID=A0A4Y1VJW6_BACUN +-sELENRIDSLLNGKKVTVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQNISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISLSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5273 TaxID=2019663 RepID=A0A2N6L0P6_9CYAN +--SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD +AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI +EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGTLMAMVSQGNLLNMASRD +RILDIMRNTVR-NHLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR +SNND-PRAEKLIGSISKATYQQf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A2L1J159_ACIBA +------------------------------------------------------------ +------------------------------TMTLAELSAAALHYSDDTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLASAAR------ +>[subseq from] class A beta-lactamase n=1 Tax=Dyella ginsengisoli TaxID=363848 RepID=UPI000A00FB82 +--RLQQALTQLASKAPGVLGVTIVDLNTGVRT-RINANRAYPMMSVFKAPVAAAVLAQVD +AGRISLNQEVTVDRQDVVSGAAVPSQFKGEHFTVDRLLVAAVSESDNTAVDALIRQVDGP +RVVTDFLRKHGIDGMRVDMGEGDIGRAYLDDPRNRTTPDAAANFLEKLWTGQLLSTRSTK +RLLGLMYGQTV-PSRLRSGLPAVVRFADKCGTSYTAAFNDIGIMTGPDGHTVIVAAFLTA +SRADKKARNAFFAKIGKDVADAy +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides TaxID=816 RepID=D4WB00_BACOV +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTI-TVNNDIPYPLMSVFKFHQALALADYMG +KQRQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP +DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANNKIIADISRIVYEY- +>[subseq from] Uncharacterized protein n=1 Tax=Armatimonadetes bacterium Uphvl-Ar2 TaxID=2004468 RepID=A0A1Y0H7F3_9BACT +-------LAAIEARSQGKLGAAVV-TAQGAHY--LHQDEKFSLQSVMKLMVAMAALEQVD +RGQWRLDQSFEFKRSDLSLHQPITQRLGRREITLDECIELMVTESCSGAADFIIRRLGGP +EKVNAFLVKHDIQGMRIDRLERDLQTRYLADPRDTTTPAAMAKLLQKLLQGQLFSPTSTR +YLLGVMERTATGQDRLRAGVPAGWTVGHKTGTSSAGATNDVGIARNKAGEWVILVALLRE +STLAPRDRDRILADVARA----- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis sp. LC363 TaxID=1120705 RepID=UPI00055C0AB5 +---LDDRIFELWRAFPGKTGIAVQRIDGEWSL-SQRGDELFPQQSVSKLWVALTVLDAVD +QGRLTLDQRVRIGPEDLTLHQPLAARVRSEGMSVRDLIETAITHSDNTANDSLLRTVGGP +DAVRAFIDKKDLGAIRFGPGERLLQAAYLANPPDGASPEAIASALTRLARGTLLSPDSTE +YLLGVMSRTRSGPRRLKAGLPAGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGD +TSASVPARMALMQAVSGAVADY- +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=UPI0004523C26 +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLKTRLLIKKSDLKPYSPLREIYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides caecimuris TaxID=1796613 RepID=A0A1C7GYN1_9BACE +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTA-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD +FIYQTMVECQTGQDRMVALLDKKVTVGHKTGTGDRNGYNDIGFVLLPDGRTYSIAVFVKD +SKENSQVNSKTIADISRIVYEY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. OV259 TaxID=1500286 RepID=UPI00055646CF +-qDFKKEINSITKDKKATVAVSVTGIDFPFEFnNKNSSKKLPMLSVFKFHIALAVLNEVD +KGKLKLDQKIFIKKTDLLEHSPIRDNFPKGNMPLSELIKYTVAQSDNNGCDILLRLIDGT +ETVQKFMNEKGVKNFQIKYNEEGMHKGKEYLYANYTTVASLNSLYKKFYEKKILSRKSTD +FLMKIMLETSTGTNKLKEQLPKGIPIAHKTGSSGKEAENDSGIITLSNGKHYAISVFVID +STETEAVNCKMISDISKAVWDQf +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPHIGHO2_02_FULL_61_10 TaxID=1797944 RepID=A0A1F9VSL7_9BACT +--AMVESLDKLSRSYRGRVGIYIRDLETGKTW-AYNAEKLFPSASLIKVPIMAAVFEKIK +LGEFTLDTQIKLTRPSRVGGSGSLKWVREGTLSVMEIVYKMITESDNTATKMLIDQV-GM +PYLSEAFKKLGLEHTNITPEGMSLSS-YRVKRENYTTPREMASLLERIYAGELVNRESSE +FMLDVLKHTKS-RSRLRKGLPLGWEIGHKTGLLRK-ACHDVGIVFSPRGD-YVIAVLTSE +AP-NYTTAKNFISKVAKLTYRYy +>[subseq from] Serine hydrolase n=2 Tax=Spirosoma sp. HMF3257 TaxID=2183553 RepID=A0A327NV03_9BACT +--RLEQELLRLSNLSAGKVGICAVHLESGRTI-TQNGKDHFPMASSYKVAIATQLLTRVD +SGSVTLDQLVPITKTDFHPGSGMLSERFNSTLSVRSLLELMLLISDNSATDICLRLAGGP +AAVNACMKRLGVDGLQVNRPTAWLIAAFENDLRDTSTPEAMTLLLTKLYTQPILKPASKT +LILDIMKRCETGLARLKGALPPDTEVLHKTGTIGL-TASDVGIITLPGDGHVAISVFVKS +SKKEGAVRERTIAEVTRTIYDYf +>[subseq from] Beta-lactamase n=1 Tax=Legionella fallonii LLAP-10 TaxID=1212491 RepID=A0A098G2M7_9GAMM +--ELAKKIDTIEKKSKSVIGITAIYIEKNKIV-GHNSNKRFFMASTIKLPIALAFLHRVD +EKQDSLNRVIKMDMKNSVPGSGSLHHLFEKKMSMQQILKYMMRNSDNSASDTVLHAVNGP +EYVKKRMDALGFKNIYVNRSILEMFLRFENDTRDTTTPEDMAKLLVKVYKKQALSEASTK +VLMNIMEQCRTGRSRIRGLLPGSVKVAHKTGTWAYRFASDVGIITLPNNGHIAIAVYVKS +QSASDYPRSRAIALASRAVYDHf +>[subseq from] serine hydrolase n=1 Tax=Porphyrobacter sp. SLTP TaxID=2683266 RepID=UPI0014120282 +--NWQQRIAELADPAQGRIGVAAVDLATGEEV-MVLGDQLFPMASTSKVAIAATFLEMVE +QGRYTLTSEFPLMMPVASAYSSTKAPVRAGQMPAIDLIEIMITRSSNPATDALLAAVGGP +AVVNDWIRRQGITNFSINRDIATLVRAVHIDTRDAATPRAMVRLLSGLYRGDFLSDQSRQ +VLLAAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGIIECPDGRTIAVAIYVTG +QG-SKEAREERIAAIARALYDGf +>[subseq from] Beta-lactamase n=1 Tax=Odoribacter laneus CAG:561 TaxID=1263089 RepID=R5VPE2_9BACT +-kDIEIQIADFVKDKKATVGVAVL-TEDDKII-QYNNSVHFPLLSVFKFHVALAVLNKLD +KQHIDLDSTIQIKASQLRAYSPLRDKFPNQDLSWKELLQYSISLSDNNACDILIDSAGGI +AAINKYIQKLGIKDFNLSATEDFMHQGIKNAYLNWSTPLEVVRLMKLAYTKELFSAPYKD +FLWKTMLETSTGANKLKGLLPENVLVGHKTGSSDRTADNDAGLVLLPHGKSFYIAVFIMD +SQETDQTNAAIIAHISKLVYE-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI0009C0BE4E +-----KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNTP +--TSELNKKIVISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI +KEFQQALIHRGDHISNPQRLEPDLNLYDPQSTDDTTTPKRAATTFNHLLQSENMSKANLE +LLKHTMIHNETGGTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK +SDKDAKPDDKVIQTAAETAIK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A286SCJ1_KLEPN +------------------------------------------MCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVG--------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides oleiciplenus YIT 12058 TaxID=742727 RepID=K9E3G2_9BACE +--GLEQQIEQVLKDKKATVGVAVLANDTIIA--LHNNQIHFPLFSVFKLHVALAVLDKMD +KEHVSLDSIMEIKAAQMLPYSPLRQKFPDQDISLRELLEYSISLSDNNACDVLIDYTDGI +EKVNSYIKSLGLKDFNLAANEDLMHRDVATQYQNWSTPEAVVRLLDIADKQTLFATEYKD +FLWQILKETSTGTDKLKGQLPPDVIVGHKTGSSDKTADNDAGFIILPDGREYYITVLVME +SQENDQENAAIIARISKIVYD-- +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Calothrix sp. NIES-2100 TaxID=1954172 RepID=A0A1Z4GS59_9CYAN +-------VQSLTAANNLAPGVLLVDLDTGSYV-DINSAASFPAASTIKVPILVAFFQDLD +AGKIRLDEMLTMQQQMIAGGSGNMQYKPAGTYTALEVASKMITISDNTATNMLIARLGGI +EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVSMRSRD +RLLDIMRQTQK-DTLLPSGLGAGATIAHKTGDIGT-MLADAGLVDIPSGKRYIAAVMVQR +PNND-PRAEKLISAISRAAYQQf +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WTI7_9BACT +--ELKKKLEHVDSSVQSEVGIGVLDLSSGESW-FLNGEQRFPMQSVCKVPVAIAILKLVD +DGALSLGQSVTINPEQYAPWSPLRDELKGGSFTVRNLLERSVADSDNTAVDVLIELAGGA +GKVDAILKAMGIRGVRVDRRERDLQTKFLSDPRDTATPEGMVHLLSQLYQNKLLSPSSTQ +LLLQIMTDTPYGQYRLKAGLPPKWSLAHKTGTGPNTGTNDAGLACAPAGQCFALTVFIAG +SKVPLQNREALMRDVAAAVT--- +>[subseq from] Cft2 n=1 Tax=uncultured bacterium AOCefta2 TaxID=654977 RepID=D6MLX4_9BACT +--DLSQRLAEIARRAGGQVGVSVMNIENGDSA-DFNGDEPRSLYSVFKFPVAVAVLKDVE +TGKLKLDQKVAVKKSDLSGTAPSSSNRWQNMYTVQQLLEFAMIESDNTAVDKLLTLVGGP +STVTKQIQSLGISGIEMAADSREAA--KLADHPNTGSANAIVRLLAGLQKGEVLKPAERT +VLWDMMQRATTGVKRLRAGLPARTVLMHKTGTGPDSGTNDVGIINLPDGGHLAIAVLINK +STLSSASQEQVIAAIAAAAWD-- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2D6A4H7_9BACT +-qDLKGLLAPLINRHRGEVSVAVKHLATGQSF-SHRADQPMPTASLIKLPIMIEAYRQAE +AGTIDLDLTITLAQADKVPGSGVLTPHFSAGLSLRDAVHLMMTVSDNTATNLVIDRI-GL +RATTDTMERMGCANTKLHSKLFRRGTRSKQFGIGSTTANEILTLLEKLHASKVVSKKASE +AMLGHMLACTD-KDKFPRFLPPGTKLAHKTGSVSS-VRCDGGIIYAPGGA-VAVCVLTKN +NRDQDNAGNRLCARIAITAYRHf +>[subseq from] Beta-lactamase n=2 Tax=Sphingopyxis alaskensis TaxID=117207 RepID=Q1GWS4_SPHAL +---LQDRIHALWSAFPGKTGIAVQRIDGEWTL-SHRGGDLFPQQSVSKLWVALTVLDAVD +QGRLTLDQRVRIGPEDLTLYQPIAARVRAEGLSVRDLIEIAITQSDNTANDSLLRTVGGP +DAVRRFIAKKDLGAIRFGPGERLLQAAYLANPPDGASPTAIANALTRLARGALLSPESTE +YLLGVMSRTKSGPRRLKAGLPADWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGD +TSAPVPARMELMQAVSSAVAAY- +>[subseq from] class A beta-lactamase n=1 Tax=Cryobacterium sp. Sr39 TaxID=1259198 RepID=UPI00141BB793 +------------------IALSAKNVRSGRQI-NHRATEPVPMCSLFKVLAVANLLRLRG +YEDQYWSTPISFTAADVVVNSPVAAASTSMTMTPNQMADAALRFSDNTAGNLLLRELGGP +ATITQFAQALGARRTRLDRIEPELNEGLPGDVRDTTTAEDMVAIMEALLIDGDAGQLARS +RLQDLMLRNTTSGTRARAGLSEPFELADKTGAGNYGIVNDAGVLWQGQRQTIAMCILTRT +EVASAPNNNDVIADATRLIVSEf +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. CCP-7 TaxID=1979270 RepID=A0A437LWC0_9SPHN +-qRLDARLEAYAQRKDIRVGIAAIHLESGATV-SVNGAEAFPMASAYKLAAVLTLLHQVE +QGRFTMTQMIPVDDALRVQSGGISTSMPHAGLSVANLIDLTITRSDNTAADMVTQMVGGP +QAITAWLKSVGIEGQRVDRDVAGLIFAFIADPRDSSTPDAMVALLTKLQQGKLVNAEHTA +WLIDVMAHTVTGAKRVKGLLPPRTVFAHKTGTLV-GICADVGILTLPGGGHVAIAVFVKS +HD-DGAKAEAIIAEVGRTIYD-- +>[subseq from] serine hydrolase n=1 Tax=Croceicoccus sp. H4 TaxID=1783232 RepID=UPI000AE4814C +---LRQQLFAVARPDKGRIGVAALDLSTGQTV-SILGDQSFPMASTSKIAIAATFLAGVD +KGIYRLDAKYPLMIPVASRSTSVAPVKPGMELTARSLIELMITRSDNTATDAMLKAVGGP +AEVTKWMRGKGFQRFRIDRDIATLVRATGADLRDSTPPDEMVRLIAGLYKGEWLSGDSTD +VVIGAMTRTVTGSRRIKAGLPSGTNFGHKTGTLNN-TASDVGFVEMPDGRVIAMAIYVTG +QG-GRPQRDARIAEITRTLYAGf +>[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI0011CD6066 +-----SAVRELAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD +QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP +QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQS +VLWNIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD +SKDSESACDRVIASMARWLCL-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=unicellular cyanobacterium SU3 TaxID=1982589 RepID=UPI000B3DD822 +-eNLQKKIEKVLKNKSATVGVAISGMDPSDTL-SINGDKRLPMQSVFKYHLALAVLHEVD +QGKFGLEDNITIDKELVDAWSPLRKKYPEGAVILAEILEYTVSLSDNLGCDILFDLIGGP +TVVEAYLHKIGIKEITIVHKEIDMQAKWERQFENWTTANTANLSLKLFFEENLLTDKSYS +FLLEILKGTKTGLKSIRGLLPKETVVAHKTGSSGTGALNNIGIVFLPDNSYFYISVFVSD +SKESNDTNQKIIAEIAKLAWDYf +>[subseq from] Beta-lactamase n=1 Tax=Flagellimonas eckloniae TaxID=346185 RepID=A0A0Q1BWV6_9FLAO +-qTLKREIYEILQDKDATVGVAISGQNPKDTV-TINGNVHLPMQSVYKYHLALAVLDQVD +KEKLSLEEKITLTKKDLDNWSPIREKYTEGTLTLAEIIEYTVASSDNVGCDLLFKLVGGP +KTVEDFLHNSGISNVAVRYDEEIQQANWDLQYENWTTAKASNKALKVFFENAQLSKESHA +FIWKTMKSSWTGANCIRGHLPKNTVIAHKTGHSGTGAQNDVGIVFLPNGTYFYLSVLVSD +SKEDSKVNEKIIADIAKLSWDYf +>[subseq from] Serine hydrolase n=1 Tax=Bosea sp. Root483D1 TaxID=1736544 RepID=A0A0Q9I8N1_9BRAD +--ELESKLKELAASHPGRVGICAQSA-GDKPV-CVNGEQRFSLQSVMKLVVGAAVMRAVD +EGKMRLDDKVTLRREDLSVIQPLADIVLKDGSTIEDLVRRAVVESDSAATDFLIARLGGV +GAVQTLLDAAELHDIRIDRTERELQTAYLSDPRDTATPLAMVRFLRKLAAGQLLSPASTK +HFLAVMSQTVTFPDRLRAGAPAGWTVGHKTGTSHNGVTNDVGLLTAPDRGFVAVAAFIAE +SRAPAPARAAVIAEAARRVTGAy +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI0006990017 +-----KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGGRFAFASTYKAISSGILLQNTP +--TSELNKKIAISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI +KGFQQALIHRGDHISNPQRLEPDLNLYDPQSTDDTTTPKRAATTLNHLLQSENMSKANLE +LLKHTMIHNETGDTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK +SDKDAKPDDKVIQTAAETAIK-- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A3D1A6M8_9BACT +--EMVEDLEKISRSYRGRVGIYIKDLETGKTW-DYNSDRKFPSASLIKVPIMAAVFEKIR +AGALSLDTQIRLTRGGRVGGSGSLKWVRDGTLSVMEIIYKMITESDNTATKMLIDAV-GM +DYLSSAFSAMGLEQTNITPEGMSLSSR-PVRRENYTTAREMGSLMERIYAGELVSREASE +FMLDVLKHTKS-RSRLRKGLPLGWEIGHKTGLLRK-SCHDVGIVFSPRGD-FVIAVLTSE +SA-NYTMAKNFIAKVAKLTYQYy +>[subseq from] Beta-lactamase n=1 Tax=Sphingosinicella sp. BN140058 TaxID=1892855 RepID=A0A4P6FT33_9SPHN +------------------------------------------------------------ +------------------------------GVSARTLMEQMITRSDNRATDLLIARLGGP +AEIHAWLRAHGLSGIRVDRTIAQLLAARRRDVRDSSTPTAMLRLLRTIDGDEALSPASRR +ILLDMMSRCRTGSNRMRALLPAGTKVEHKTGTLS-GYTGDVGFVTLPDGRRIAVALFARG +GV----NRPAVIASAARTIYDAf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Colwellia sp. 20A7 TaxID=2689569 RepID=UPI00135727ED +-eSLKQQINSLLEGKNATVGVAILAGDGSEYI-SINGNKKLPMQSVFKYQLALAVLDQVD +KNNLSLSDRISISPKDLDNWSPIRKEYPDGALSLAEVLKYTVAYSDNVGCDILFNIVGGT +KVVEAYLHKQGIMDVAIEYDEITQQLVWDRMYENWTTANAAIAVLKLFYENKLLSQNSHQ +FLWDTMKISGTGKDKIKGLLPKGTIVAHKTGSSGTGAENDIGIVFLPDGTHFYISVLVSN +STEKSAVNKKLIADVSKVTWDYf +>[subseq from] Beta-lactamase n=1 Tax=Croceicoccus ponticola TaxID=2217664 RepID=A0A437GZ80_9SPHN +---LKQNLFAVARPDKGRIGVAALDLSTGQSV-SILGDQSFPMASTSKIAIAATFLAGVD +KGIYRLDSKYPLMIPVASRSTSVAPVKPGMELSARSLIEMMITRSDNAATDAMLKAVGGP +AEVTKWLRAHGFQKTRIDRDIATLVRATTVDVRDSTPPEEMVKLVAGLYQGQWLSQSSRD +VVIGAMTRTVTGRGRIKAGLPTGTSFGHKTGTLNN-TASDVGFVKLPDGRVIAMAIYVTG +QG-GRPQRDARIAEITRTLYSGf +>[subseq from] Class A beta-lactamase n=1 Tax=Spirosoma sp. KCTC 42546 TaxID=2520506 RepID=A0A515A3U7_9BACT +---IEQELLRLSNLSAGKVGICAVHLESGKTI-TQNGKDHFPMASSYKVAIATQLLTRVD +SGSLSLAQLVPIVKTDFHPGSGMLPNSPNSDLSVRSLLELMLLISDNSATDLCLRLAGGP +AAVNACLKRLGIEGLRVDRPTAWLIAAFENDLRDTSTPEAMTLLLTKLYTQPVLKPNSKA +LLLDIMKRCETGLARLKGALPPDTEVLHKTGTIGL-TASDVGIITLPGDGHVAISVFVKS +SKKEGSVRERTIAEVTRTIYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Saprospirales bacterium GYS_P2D TaxID=2692196 RepID=UPI001359A01A +---VQSAIEEMIKSYDATVGVSIYEPKSGDQI-SVNGDRHLPMQSVYKLHLALTVLKDVD +AGICSLSDSIQITPAHIEQWSPLKKKYPNGAITIAEMMEQTVAWSDNMGCDILFEMVGGP +AIVEKYMRDIGITDVAIRYPEIIMQSDWEIQYLNWSTADAITLLLQKIYTNKMLSETSYD +YLMETLIGTQTGTKSLRGLLPEGTTIAHKTGQAGRGAVNDVGIIFLPDGSPLYISVLVSD +SREKLDDCYHIIAQTARIAWDHy +>[subseq from] Beta-lactamase n=1 Tax=Legionella tucsonensis TaxID=40335 RepID=A0A0W0ZPA8_9GAMM +--ELIKKIKDIEQKSNTVIGLAAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD +EKKDSLNRMIRMDSRNSVPGSGALHYLFEKKISLEQILMHTLKNSDNSASDALLQAVNGP +QYVAKWMNALGFKNIFINRSIMEMFIRFEKDIRDTTTPDDMAKLLVKLYKKQVLSESSTD +LLMKIMEQCRTGRSRIKGLLPANVKVAHKTGTWSYRFVSDVGIITLPNKGHIAIAVYVKS +KSASDYPRSRAIALASRAIYDHf +>[subseq from] Penicillin-binding protein n=1 Tax=Hapalosiphon sp. MRB220 TaxID=1704290 RepID=A0A0M0SH08_9CYAN +--SLKTNLQSLASANNLTPGVFVVDLENGSYV-DINASASFPAASTIKVPILLAFFQDVD +AGKIRLDEMLTMEKEMMVGGSGDMRNKPAGTFKALEVANKMMTISDNTATNMLIARMGGI +EALNQRFRSWGLNTTVIRNQLPDLDGT------NTTSPKELGNLMAMVNQGNLISMTSRD +RILEIMRNTVR-NQLLPAGLGQGATIAHKTGDIGS-MLADAGLVDLPTGKRYIVAVMVKR +PNND-PSAEKLIGSISKATYQQf +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. FSY-9 TaxID=1908524 RepID=A0A437N0Q3_9SPHN +----ETRLAHLADASNGRIGVAAVDLGSGQGV-SVMGDQPFPLASTGKIAIVAAFLEGVD +QGRYRLNDRYPLMVPVPSRSTAVAPVRPGAMMSAEQLIELAITRSDNHATDALLAAMGGP +QVVTRWLRRVGVSGIRLDRDIATMVRARSIDLRDSTTPQAMAVLLAGLYQGQWLSAQSRE +VLLGAMRRCVTGIHRMKALLPDDALIGHKTGTLSN-TSSDVGLIRTSDGRTLAVAIYVTG +QG-GKPGREQRIAAIARALYENy +>[subseq from] Beta-lactamase n=1 Tax=Odoribacter laneus YIT 12061 TaxID=742817 RepID=H1DJM3_9BACT +-kDIEIQIADFVKDKKATVGVAVL-TEDDKII-QYNNSVHFPLLSVFKFHVALAVLNKLD +KQHIDLDSTIQIKASQLRAYSPLRDKFPNQDLSWKELLQYSISLSDNNACDILIDSTGGI +AAINKYIQKLGIKDFNLSATEDFMHQGIKNAYLNWSTPLEVVRLMKLAYTKELFSAPYKD +FLWKTMLETSTGANKLKGLLPENVLVGHKTGSSDRTADNDAGLVLLPQGKSFYIAVFIMD +SQETDQTNAAIIAHISKLVYE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingobium limneticum TaxID=1007511 RepID=A0A5J5HSW4_9SPHN +--KLLAEFTRFSTLSDGTVGVAVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRIFALVD +AGEVRLDDQLALDPALASEGIAWMFNRPGATLSVDRLLELMLQKSDNNATDVLVARAGGP +QAITAFVTKLGVTGLRVDSDTAHLLYAFAMEPQDTATPTAMLDLITAYESGRALSAASTQ +RLFTIMAHCETGKARIVGMLPPGTAVAHKTGSLN-GTGNDVGIVRLPDGRRFAVVVFVMK +DSKGHVSRDRIIAEASRAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SLZ6_9BACT +-sELENRIDSLLNGKKSTVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium Pla175 TaxID=2528009 RepID=A0A518DAL2_9BACT +hdALQDAVAQLIKLHRGVVGAAAKQLDTGESF-AWNADQPMPTASLIKLPIMLTAYRQID +AGELSPDATIELRKQDKVPGSGVLSEHMSAGFSLRDAIELMIVFSDNTATNLVIEKT-GL +PATSALMRKLGYPETQLHSKVFLRETRSQKYGLGSTTAADMIRLLESLYKGDAASSESCE +AMLGHLRRCDD-RSKVPRYLPEEVEVAHKTGSVS-ATRCDAGIIESKGG-PLAFCILTTD +NAGAENEAELLAAAFGKTLYDHf +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium Pla175 TaxID=2528009 RepID=A0A518DAL2_9BACT +------------------AAYAIADAANGELLwGMNDSEARDPASVTKIMTAHLVLKLAE +SDPEVLDEEIVFSTVADETPGSTSGVRAGETVTVRELLYGLMLPSGNDASVAFAEHFGDG +GPYEGFIRAMNAEAKRLGMKETGYNTSGLTAKGHVTSARDMARLAHAAMKSPVLR----- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=3 Tax=Akkermansia muciniphila TaxID=239935 RepID=A0A411SPD6_9BACT +------SAVQLAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD +QGAMNLEQIIRIRQEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP +QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQS +VLWNIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD +SKDSESACDRVIASMARWLCL-- +>[subseq from] CblA-3 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=C8C145_9ZZZZ +-sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKXYIAAFVMX +SYETDEDNANIIARISRMVYDA- +>[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter seohaensis TaxID=266951 RepID=UPI000C226B71 +heRLEARLREIGGTFSGEVGIAAVEVASGATM-AYNGDRPFPQQSVSKLWVALTALDLVD +EGALDLSEPAAIRREDLTVYQPIRDIVRTRGTDYRDLMERALTQSDNTANDRLLRRVGGP +QAVDAFIRRKGIEGVQFGTDERSKQSDYLHDPIDGASASAMAQALARLARGELLSPRSTK +FILSTLENTKSGPKRLKGGVPSGWSIAHKTGTGQHSGYNDVGVLTAPDGRQYALAVMIAR +TRTSYAARFEMMQSVTRAVVEY- +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroides fragilis TaxID=817 RepID=F7LMZ5_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNEIGFILLPDGHAYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=UPI000EFDC465 +--SLETQLKEAIKDKKAEIGIAVI-TDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA +KRNQSLDTLLRIEKTDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP +DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD +FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEESFAENSKIIADISRIVYEY- +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter sp. NS1 TaxID=2338327 RepID=UPI000EA99982 +--ALERTVAQIANGSGGRIGVYAVDLASGREV-SVLGDQRFPMASTSKIAIAATFMEGVE +KGRWTLSSEFPLMVPVASAFSSTKAPVVPGKYSAVDLIEMMITRSSNPATDALLKVVGGP +AAVNAWAARNGMPDFNITRDIATLVRAQRIDVRDSATPQTMGRLLAGLYQGKFLRESSRR +VILGAMERCRTGARRIKGMLPSGVQVAHKTGTLNN-TASDIGIMHTPDGRAIAVAIYVTG +QG-SKPARDAKIASIARALYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI000F0B5EC4 +-----SAVRELAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD +QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP +QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILAGGTQN +FLWGIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD +SKDSESACDRVIASMARWLCMEw +>[subseq from] Beta-lactamase n=2 Tax=Akkermansia muciniphila TaxID=239935 RepID=A0A410E2S3_9BACT +------SAVQLAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD +QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP +QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQS +VLWNIMAGCSTGPERLKGQLPQDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD +SKDSESACDRVIASMARWLCL-- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X7G9_9BACT +--ELSARLKDICERAGGRCGVAVTHVETGRGA-AFEGATPLPLYSVFKLPLAVAVLKEVE +EGRLQLDQKVRVEPEETVPGTEENSALWRQPRPLRELLEFSIARSDNTSTDKMLELVGGP +EAVTRRMRALGLDHIEVRSTVKEFLKS-RDAHPNTGAPEDLARLLVLLRKGEVLAPPQSA +LLLGIMARTVTGDRRLRAGVPAGTPVADKTGSGPS-TTNDVGVVTLPDRGHLALAVLLDG +SKLPSKQQEDLIAEVARAAYEA- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Aminicenantes bacterium TaxID=2052149 RepID=A0A523WX73_9BACT +-eRLKKQIEGVIRGTEGEVGVAVKHLESGQEL-YINGDMNFPMASVFKVPILVEVLAQIK +EGKFTLKDEISIQKTDQHLGSGMLSDLEAPGLSLRNLITMMMIISDNSATDILLTKV-GA +ENVNNRLRSYGIGKITVNRTCQHLIMKFSQIMKDQSTPRAMNRLLEMIYKKDVLNEESCD +LILSVMLECQTGKGRIKGDLPGRTKVAHKTGTIG-GTVNDSGIIYLPDNGQVALTIFTKD +MTLKGKDVDQIIAQIAKFVYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingobium estronivorans TaxID=1577690 RepID=UPI00123A0172 +---LMGEFARFATLTDGTVGIAVRDLSSGETL-AYNGDTLFPMASTYKVAVAAKIFSLLD +AGSLNLDEKLT---------------RLGRPLPVRTLLEMSLTQSDNEATDALVARTGGP +QAVNDWVRSIGVKNLRVDSNTRDLLAGFAMDPRDTATPRAMDDLLVAIRSGKALKPQSTA +MLLSIMERCKTGKDRLRAMLPPGTRIAHKTGTLN-GIGNDVGIVTLPDGRLFAITVFVMK +DYKGHQMRDRIMAEAARAAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter aquimixticola TaxID=1958945 RepID=A0A419RRF2_9SPHN +-dALAAEIDRLALDFGGSVGLAVVDVQTGWHT-GYEADQLFPQQSVSKTWVTLTALDQID +KGELDLARKVTLTRDDLAVYQPIRKEILRSGTDVADLIERAITQSDNTANDALLNIVGGP +DAVRQTIVDKGLGQIRFGPGERAMQSRYLSNPVDGATPLAIARALAKLTRGELLSETATA +YFLTTLERTKSGPRRIKAGAPDGWRVAHKTGTGQQSGYNDVGLITAPDGSSYAIAVMIGE +TRKPTPERMALMQAATRAVAEY- +>[subseq from] class A beta-lactamase n=1 Tax=Dyella sp. DHC06 TaxID=1770545 RepID=UPI00102EB829 +--RLQQALDAAVQGSPGTLGVAVLDLRTGATV-GVHADQPFPMMSVFKAPVAAAVLARIE +AGSLSLSQEVTASRDDLQEGSAVPGKEVKAGFTIERLLKGAVSESDNTAVDILLRVMGGP +QAVMAFLHAHGIDGMRVDVDEAGVSRAFLADPRNRSTPAGAVEFLRKLQGGELLSPTSTQ +YLLRLMAAQTK-PNRLRVGVPQGVQFADKAGTSATAAYNDIGIMSWPDGRIVIIAAFLSD +STASGKERDALFADLARSVA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2S1Q3T6_KLEPN +-----------------------------------------------KGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTAND-------------------- +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides fragilis TaxID=817 RepID=Q64WX6_BACFR +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLETRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQGRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHVYSIAVFVKD +SEADNRENSEIIAEISRIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. P6W TaxID=1609758 RepID=A0A2Z5E754_9SPHN +-----QQLAAVANASQGRIGVAAMDLTSGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD +KGKWSLTSEFPLMVPVGSASSAVAPVRAGEYMSALRLMELMITRSNNYATDALLKVVGGP +KAVNAWVERAGIDDWHIDRDIATLVRARVVDTRDSATPYAMVQLLSGIYQGKWLSPSSRS +ALLGAMSRCVTGKRRIPAGLPEGAQVSHKTGSLNN-TSSDVGIVQTPDGRVFAIAIYVTG +QG-GRPGRESRIASIARTVYNGy +>[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium sp. CA7 TaxID=2604424 RepID=UPI00129532FD +--TLTQKIENIISGKKADVGVSVIGVQKNDKV-QINGEKFYPMLSTFKFPIALTTLHQVE +KGKLRLDQKMLIKKEQLLEWSPFREKYPEGNITLEDALQWMMCYSDNNLTDIILRLIGGT +EPVQKLIGS----DFIIKNDEEGMHKDWDSQFINTITPNKAANLLEKFYQGKILNKARTQ +WLYNAMLNNQTGLKRLKGKLPANVKVAHRSGTSFTGAVNSYGIIELPHNKKIVVAVFVHN +TYESFDNAEAIIADISKAAYDHy +>[subseq from] Beta-lactamase n=1 Tax=Paraprevotella clara YIT 11840 TaxID=762968 RepID=G5SR83_9BACT +--DLQEQLRRMVADKKAQVGIAVI-VDGSDTL-TVNNDVRYPMMSVFKFHQALAVADACG +RRGVSFDTLVYIRPDDLRPYSPLRDKYPEGNLSVGELLKYTLHLSDNNACDILFRVFGGP +AATDEYLRSMGLRDFAIEATEDDMHRNLADCYRNWTTPLEAVRLLEWLVSGKAAKGAYRD +FIEQTMISCQTGRDRLPAPLATKAVIGHKTGTGDRNGTNDIGFVFLPDGRRYSIAVLVRD +SEESEQATARIIADVSEAVYRY- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A5M6AKV4_9BACE +--SLETQLKEAIKDKKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA +KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP +DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD +FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEESFAENSKIIADISRIVYEY- +>[subseq from] class A beta-lactamase n=1 Tax=Pedobacter miscanthi TaxID=2259170 RepID=UPI001314E112 +-kKLEVTVAEIAADTRGKIGIYARVLESNETF-EFNNNQHFVMQSVFKFPIAVMLLSEVD +KGKFNLDQQVFIPKSKIKKTSKLYEKYPEGNVPLREILEDMVLYSDNNACDVILQLLKGP +RALTRYLHGIGITDINVDFDEWGMQKKWNNQYQNWCTPQAQVTLLKLVFEQKLLKSETNT +LLRTLMRKTYVAPMRIRGLLPKGTLVEHRTGTSATNATNDVGTITLANGKHLAIAIFLMD +SYENNEKRDLIIAKIAKAAVDEf +>[subseq from] Beta-lactamase n=2 Tax=unclassified Novosphingobium TaxID=2644732 RepID=A0A4R1W8M1_9SPHN +---FGKQLAAVAEASQGRIGVAAMDLSSGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD +KGKWTLSSEFPLMVPVPSASSAVAPVRAGTYMSARQLIELMITRSNNYATDALLKVVGGP +SAVNAWVRRTGIDDWHIDRDIATLVRAKVVDKRDSATPIAVVQLLSGIYQGKWMSQQGRD +VLLGAMSRCVTGKRRIRAGLPAEVSVSHKTGSLNN-TSSDIGIIETADGHAYAVAIYVTG +QG-TRPNREARIASIARTIYNGy +>[subseq from] class A beta-lactamase n=2 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI0011782736 +-----SAVQELAHSLKARVGMAAEMLDTGETV-AVGDEAAYPMQSVVKFVLALSVLKRVD +QGVMNLEQIIRIRPEQLVKWSPLRERSPQGGFSLKELLKVTVQESDNNTCDLLFSLIGGP +QAVQKDLTEWGIDGINVRFTEDEIHRNRDLQYANSSRPSAMNSLLRAFDEGKILKKGTQH +VLWDIMAGCSTGHERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSMFIRD +SKDSESACDRMIASMARWLCMEw +>[subseq from] Beta-lactamase n=2 Tax=Erythrobacteraceae TaxID=335929 RepID=A0A0P7W274_9SPHN +--SFEQRIAELADGSQGRIGVAAVDLATGEEI-AVLGDQLFPMASTSKIAVAATYLDMVE +KGQFSLTSEWPLKIPIRSAFSTVAAPVREGSMQAIELIELMITRSSNPATDALLAAIGGP +AKVTEWVHRQGIEEFSIDRDIATLVRANWIDPRDAATPRAMVRLLQGLYRGDFLSDTHRK +VLLGAMSRTVTGQRRIVANMPEGASVSHKTGSLNN-TSSDIGIIEYPDGRAIAVAIYVTG +QG-TRLARERRIAAIARALYDGf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D5CAG8_ECOLX +------------------------------------------MWQTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDRTG----------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Thermosynechococcus vulcanus TaxID=32053 RepID=UPI000F8D3BB9 +--NLQQQIQQLVSRQNLTAGLYFFNLDSGASL-NVGGDQVFPAASTIKFPILVAFFKAVD +EGRVTLQERLTMRPDLIAPEAGTLQQKPNSQYAALEVAELMITISDNTATNMIIDRLGGA +AELNQQFQEWGLENTVINNPLPDMKGT------NTTSPRDLATLMLKIGQGEILSPRSRD +RLLDIMRRTVT-NTLLPAGLGKGATIAHKTGDIGI-VVGDAGMVDMPNGQRYVAAMMVKR +PYND-PRGSELIRQVSRMVYQAf +>[subseq from] serine hydrolase n=1 Tax=Erythromicrobium ramosum TaxID=35811 RepID=UPI001324815B +--NWQQRIAELADPAQGRIGVAAVDLATGEEV-MVLGDQLFPMASTSKVAIAATFLEMVE +KGRYTLTSEFPLMMPVASAYSSTKAPVRAGQMPAIDLIEIMITRSSNPATDALLAAVGGP +AVVNDWIRRQGITNFSINRDIATLVRAVHIDTRDAATPRAMVRLLSGLYRGDFLSDQSRQ +VLLAAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGIIECPDGRTIAVAIYVTG +QG-TKQAREERIAAIARALYDGf +>[subseq from] Tll2115 protein n=2 Tax=Thermosynechococcus elongatus TaxID=146786 RepID=Q8DH45_THEEB +--NLQQQIQQLVSRQNLTAGLYFFNLDSGASL-NVGGDQVFPAASTIKFPILVAFFKAVD +EGRVTLQERLTMRPDLIAPEAGTLQQKPNSQYAALEVAELMITISDNTATNMIIDRLGGA +AELNQQFQEWGLENTVINNPLPDMKGT------NTTSPRDLATLMLKIGQGEILSPRSRD +RLLDIMRRTVT-NTLLPAGLGKGATIAHKTGDIGI-VVGDAGMVDMPNGQRYVAAMMVKR +PYND-PRGSELIRQVSRMVYQAf +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium arthrosphaerae TaxID=651561 RepID=A0A1B8ZSH7_9FLAO +--DLTQQLTTLIAGKKADVGVSIIAPYKREII-QINGNRLYPMLSTVKFPIALTILHKVE +KGELSLQQKLFIKKEELLEWSPFKKEYPEGNISLEDAIKWMVSYSDNNLTDILLRLIGGP +EPVQKFINS---KNFIIKNNEEDMHKDWQSQFINTITPNEATRLLEKFYNGKFLNKKHTQ +WLYMAMINNASGAKRIKGNLPKTVKVAHRTGTSFTGAVNDFGIIELSDKERIYIAVFVHD +TYETFENAEAIIADIAKATYDYy +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. G0186 TaxID=2487064 RepID=A0A3G6PPQ8_9FLAO +--ELKKLIEAIISGKKADVGVSIIGLSKKEVT-QINGNKFYPMLSTVKFPIALTILHQVE +KGELSLHQKIYIKKEELLEWSPFKKEYPDGNLTLEEAMKWMVSYSDNNLTDILLRLIGGP +ESVQKFITS---KSFIIKNDEEGMHKDWDSQFINTITPNEATRLLEQFYNGKILNKEHTK +WLYTAMLNNVSGAKRLKAHLPKGVKIAHRTGTSFTGAVNDFGIIELSDKKRFYIAVFVHD +SYEKFEDTEAIIADIAKAATTHy +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3A0DRR8_9BACT +-dELADKIQPLVDAHRGRVAVAIKDLKTGASF-EHNATEAMPTASLIKFPLMIAAYQAVE +EGRLTLDDKLTLAESDKVPGSGILTPHFSAGISLRDAIELMIVYSDNTATNLVAEKV-GL +AATAELMEKLGCPETKMNAKVFRRDTRSKQYGLGSTTAADMVKLLEQLSDKKLVSGAASE +KMLAHLYACED-KQKFPRYLP-GVKIAHKTGSVNE-VRTDAGLIDAPSG-PIAICVLTNE +NQGDRNEAEILCGKIAQIAYRHf +>[subseq from] Beta-lactamase n=2 Tax=Dyella sp. 4G-K06 TaxID=1927958 RepID=A0A370WYV7_9GAMM +--RLQRALTRLAAEAPGMLGVTVLDLDAGTAV-RVNADRAYPMMSVFKPSVAATVLAKID +AESISLDQTVTVARKDVEDGAPSIGAHFTGEFTVRRLLAAAISESDNTAADALVRLVGGP +RVVTAFLRAHGIDGMRVDLDEAGVSRAYLNDPRNRTTPDAAADFLKKLWQGRLLSPGSTR +RLLDLMYGQTI-PARLRNGLPPGVRFADKCGTSYTAAYNDIGIITWPDGHTVIVAAFLTA +SHADKKHRDALFAQIAREVS--- +>[subseq from] Beta-lactamase n=2 Tax=Moorea TaxID=1155738 RepID=A0A1D8U312_9CYAN +----------LVKDKVGTAGVAARPVEGGCLI-LLNAKKWFPMASTVKLPIAMALLDQVD +AGNLRLDTLVEIDDSEWVLSPVVASEFVHPGLSVANLIEVMITLSDNTTTDVCLRLVGGP +DAVDDYVTSLGIKGMDISRYMRGLLKAFEADPRDQVKPLAMLDLLLKLFNGDALSPDSTQ +FLLGIMGRTKTGSGRLKGLLPSGILVEHKTGTVG-GVANDVGYIRLPDGRRVAIAVFTKS +STKAPQERERAIAEIGRLLFDVy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A349ZX58_9FLAO +------EIVEIMTGKKATVAVSVLDFQDCTSY-HLNAGNSMPMLSVFKFHIALAALDQVD +KGTLQLKQEFLIKKEDLKEYSPVRKLYPDGNLTLEKILYYMVAESDNNLTDYLLNLLGGP +DYVHQYIKNKGVRDTYIRADEDVMHKGFKYMYLNTTTSKAATDLLQKFYKGNILSKASTE +TLLNIMFATSTGANKLKALLPVGTQIAHKTGSSGKDAENDIGIIVLPSGKVYAIAVFIKD +SKESEEINTKMIAAISSAVNQYf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A412FXN8_9BACE +--SLETQLKEAIKDKKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA +KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP +DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD +FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEESFAENSKIIADISRIVYEY- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A174I1I3_9BACE +--SLETQLKEAIKDKKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA +KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP +DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD +FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEESFAENSKIIADISRIVYEY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=F1DI14_ECOLX +-----EQIKQSESQLSGRVGMIEMDLASGRTQtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGSTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAAT---------------- +------------------------------------------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium arthrosphaerae TaxID=651561 RepID=UPI000F4F644D +--DLTQQLTTLIAGKKADVGVSIIAPYKREII-QINGNRLYPMLSTVKFPIALTILHKVE +KGELSLQQKLFIKKEELLEWSPFKKEYPEGNISLEDAIKWMVSYSDNNLTDILLRLIGGP +EPVQKFINS---KNFIIKNNEEDMHKDWQSQFINTITPNEATRLLEKFYNGKFLNKKHTQ +WLYMAMINNASGAKRIKGNLPKTVKVAHRTGTSFTGAVNDFGIIELSDKERIYIAVFVHD +TYETFESAEAIIADIAKATYDYy +>[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5268 TaxID=2019662 RepID=A0A2N6KAS6_9CYAN +--SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD +AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI +EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGNLMAMVSQGNLLNMTSRD +RILDIMRNTVR-NHLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR +PNND-PRAEKLIGSISKATYQQf +>[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A1G6G538_BACOV +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP +NAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIADISRIVYEY- +>[subseq from] ClassA n=3 Tax=Bacteria TaxID=2 RepID=A0A127SGP2_9BACT +--QFESRLDEILSGHKAFVGVAVR-TPGGETI--ARNDTLLPMMSVFKFPVALAVLDRMQ +REGIPLTQPISITPDLLLPYSPMRDSLPAGGLTLGQLLRYMVSESDNIACDILLREAGGP +EAVEAYVRSLGIGGIRIAASEEEMHRGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA +LLQRLLRGTTTGANKLKAGLPASTVIGHKTGSSDRTADNDVGYVVLPDGRRYCIAVFVTE +SEENDATNAAIAASASRAAYEYf +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A0D5CA69_ECOLX +------------------------------------------------VMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGAGG-------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingobium abikonense TaxID=86193 RepID=UPI000789471A +--KLLGEFERFATLSDGTVGIAVRDLQTGETQ-AINGDTLFPMASAYKVAVAGRIFALID +AGDVRLDDQLALDPALASEGIAWMFSRPGASLSVQRLLELMLQKSDNNATDVLVARAGGP +AAITQFVRGLGVDGLRVDSDTAHLLYAFAAEIEDTSTPRAMLDLLTAYESGKALSAGSMQ +RLFTIMAHCETGKARIVGMLPPGTAVAHKTGSLN-GTGNDVGVVRLPDGRRFAVVAFVMK +DSKGHKSRDRIIAEAARAAYDYf +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=2 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A395VYM2_BACOV +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP +DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIANISRIVYEY- +>[subseq from] Beta-lactamase n=2 Tax=Staphylococcus cohnii TaxID=29382 RepID=A0A658S140_STACC +-----KSFDQIEQDNDTIIGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNRP +--TSELNKKIAISKGDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI +KEFQQSLIHRGDHISNPQRLEPDLNLYDPQSTDDTTTPKRAATTFNHLLQSENMSKANLE +LLKHTMIHNETGDTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK +SDKDAKPDDKVIQTAAETAIK-- +>[subseq from] Beta-lactamase n=1 Tax=Paraprevotella clara CAG:116 TaxID=1263095 RepID=R5NKQ1_9BACT +--DLQEQLRRMVADKKAQVGIAVI-VDGRDTL-TVNNDVRYPMMSVFKFHQALAVADACG +RRGVSFDTLVYIRPDDLRPYSPLRDKYPEGNLSVGELLKYTLHLSDNNACDILFRVFGGP +AATDEYLRSMGLRDFAIEATEDDMHRDLADCYRNWTTPLEAVRLLEWLVSGKAAKGAYRD +FIEQTMISCQTGRDRLPAPLATKAVIGHKTGTGDRNGTNDIGFVFLPDGRRYSIAVLVRD +SEESEQATARIIADVSEAVYRY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D5C9H1_ECOLX +--------------------------------------------------AAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGFG------------------------ +----------------------- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A4V1YZE1_9BACE +--SLETQLKEAIKDKKAEIGIAVI-INEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA +KRNQSLDTLLKIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP +DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD +FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEESFAENSKIIADISRIVYEY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=UPI0011065365 +--SLETQLKEAIKDKKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALANYMA +KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP +DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD +FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEESFAENSKIIADISRIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=Q45118_BACFG +---LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH +HQKQPLETRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN +FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHVYSIAVFVKD +SEADNRENSEIIAEISHIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=Legionella wadsworthii TaxID=28088 RepID=A0A378M285_9GAMM +--ELLKKIKEIERKSNTIIGISAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD +EKKDSLDRMIKMDSRNSVPGSGGLHYLFEKKISLKQILMHTLKNSDNSASDALLKAVNGP +RYVAKRMKDLGLQNISINRSIMEMFIRFQKDVRDTTTPNDMAKLLVKLYKKQALSEASTN +LLMKIMEQCRTGRSRIRGLLPGNVKVAHKTGTWSYRFVSDVGIITLPNKGHIALAVYVKS +KSASDYSRSRAIALASRAIYDHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=V5W480_ECOLX +------------------------------------------------------------ +-------------------------------MVLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAA------- +>[subseq from] class A beta-lactamase n=1 Tax=Agromyces sp. ANK073 TaxID=1766800 RepID=UPI0013596D74 +---------------------------DRRAF-RYRAADLFPMCSLFKPLAAAALVRARG +YDDAYWSTPIPFTDADVVRDSIVLSTLRPRQATPEQLADAAIRFSDNTAGNLLLRELGGP +AAITAFATELGATHTRLDRWEPDLNEARPGDVRDTTTPDDIAALYSALLLEDAAGVLASS +RLREWMLRTTTSGARMRAGLTAPYELADKTGGGEYGVVNDAGVLWRPGLEPTTLVILTRT +DRFDAVRNNEVVAEATRIVV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinokineospora auranticolor TaxID=155976 RepID=A0A2S6GT05_9PSEU +------------------------------------------------------MLRRAE +ADPGYLDKLVRYDRSRLEEYAPVTGERVDTGMTVAELCAASVGVSDNTAANLLFDEVGGP +AGATAFVRSLGDDITRMDRNETSLNVGAPGDERDTTTPRRIVETYRALLLGTALAPTGRD +RLTGWLVGSTTGKDLVRAGLPADWRAGDKSGSGAAGEVNNVAIAWPPGRGPWLIGVYTAP +TKA-EPPARPIVAEAARIVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Dyella sp. 4M-K27 TaxID=1927959 RepID=A0A3S0R3H3_9GAMM +-kQLQHALLNLAQRAPGLLGITVLDLDTGVQV-RINADRAYPMMSVFKAPAAAAVLALVD +AGKLSLDQTVTLTRADVVDGSPSIGAHFRGDFTLAQLLTAAVSESDNTAADALVRLAGGP +RAVTGYLLAHGIDGLHVDLDEAGIDRAYLSDSRNRTTPDAAADFLNKLWKGQLLSPSSTR +RLLQLMYAQTT-PSRLRAGLPEGVRLADKCGTSATAAYNDIGIMTWPDGHTVIVAAFLTA +SHMDRAGRDAVYVDIAQSIVQ-- +>[subseq from] Beta-lactamase n=1 Tax=Microbacterium sp. Y-01 TaxID=2048898 RepID=A0A3G8VIH9_9MICO +----------------------AVDTGTGESV-SYGEDRRFGFASTIKAFAAAVFLQSVP +--GAARDEMVHWTAEEAAAHAPVTSQHVEDGLTYAQLAEAAVRVSDNAALNLIVDRIGGS +AALDDALAELGDATTEVVNDEPTLNTIEPGSTDDTTTAAAFTASLTRILDGSTLSAADAA +LLVDWMSDNRTGDALIRSGAPAGWTVADKSGGAGP-IRNDIAVVTRPGQDPIIITVLTSR +NDPHADFDDTLVASAASITL--- +>[subseq from] Class A beta-lactamase n=1 Tax=Pedobacter miscanthi TaxID=2259170 RepID=A0A366KW83_9SPHI +-kKLEVTVAEIAADTRGKIGIYARVLESNETF-EFNNNQHFVMQSVFKFPIAVMLLSEVD +KGKFNLDQQVFIPKSKIKKTSKLYEKYPEGNVPLREILEDMVLYSDNNACDVILQLLKGP +RALTRYLHGIGITDINVDFDEWGMQKKWNNQYQNWCTPQAQVTLLKLVFEQKLLKSETNT +LLRTLMRKTYVAPMRIRGLLPKGTLVEHRTGTSATNATNDVGTITLANGKHLAIAIFLMD +SYENNEKRDLIIAKIAKAAVDEf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI000D19D12E +-----KSFDQIEQDNDTIVGVYGVNTANGKVV-QHKSGERFAFASTYKAISSGILLQNRP +--TSELNKKIAISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI +KEFQQALIHRGDHISNPQRPEPDLNLYDPQSTDDTTTPKRAATTFNHLLHSENMSKANLE +LLKHTMIHNETGDTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK +SDKDAKPDDKVIQTAAETAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter soli TaxID=1739690 RepID=UPI00136AA72B +-kALHEEIRALGKSFDGEIGLAVRDVASGWTA-HYEGNDRFPQQSVSKLWVAIAAMTLVD +RGKLDLKQEVTLTREDLTLHQPLRALALRPQTTLEDLLVKAITRSDNTANDYLLRRVGGP +NAVRTVLAELGIAGVRFGPGERIMQSAYIADPVDGATPIGMVDALARLQKGQLLSPASTA +QLLGILEQTRSGAQRLKGGLPPGWTIGHKTGTGQQAGYNDVGILTAPSGRTYAVAVLMGR +ASQPQPVRRALMHALVRVIAEY- +>[subseq from] Beta-lactamase n=1 Tax=Pedobacter sp. TaxID=1411316 RepID=A0A519WG84_9SPHI +---VSKKVDSIVTSKRAIVGFSVYILETGDTL-SLNGSRHFPMQSVYKFHLALVVLEMVD +RGKLSLGQKVLLKKADLPPHSPLRDKYPNGNVSVDELLRYTVGQSDNNGCDILFKLVGGP +KVVDQYMKKIGIKDVAVVGTEAQMHADYMMQFKNYSSPKASTNLLLKFFQGKILKAGTTE +YLMKIMQESASGPNKLKGLLPAGTLVAHKTGYSGY-ATNDIGIVTLPNGNHMLISAFVMM +SKETEAVNDRLIAELAKLAFDKy +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter aquimixticola TaxID=1958945 RepID=A0A419RVD0_9SPHN +--AVQQRISQLAEGSQGRIGVAAIDLTTGESI-SILGDQRFPMASTSKIAIAATFLEGVD +QGRWSLTSEFPLLWAVRSRFSSAAAPVRQGEMTAHRLIDLMITRSSNPATDALLAAVGGP +QAVNDWARRAGLEDFSLDRDIATLVRVTYIDRRDSATPNTMVQMLAGIYQGRWLSGTSRN +VIISAMERCRTGTRRIPAQMPSYVNVAHKTGTLNR-TASDIGIIEMPDGRAIAMAIYVTG +QSANRLRRDARIASIARGIYD-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides sp. D22 TaxID=585544 RepID=D7J8T3_9BACE +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDIFFDYQGGP +DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIADISRIVYEY- +>[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=Bacteroides TaxID=816 RepID=A0A413EP36_BACOV +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTI-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP +NAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIADISRIVYEY- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A413V1G0_BACOV +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIADISRIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. (strain 113P3) TaxID=292913 RepID=A0A0M4D6J6_SPHS1 +---LEQRIFELWRSFPGKTGIAVQRIDGEWTL-QQRGDELFPQQSVSKLWVALTVLDAVD +RGALTLDRKVTITPADLTLHQPIAARVRAEGMSVRELIETAITHSDNTANDSLLRTVGGP +DAVRRFIAAKDLGAIRFGPGERLLQSNYLANPVDGASPSAIARALTRLARGTLLSPESTD +YILGVMSRTRSGPNRLKAGLPSGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGS +TTASIPQRMVLMQAVSGAVAE-- +>[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium J003 TaxID=2420340 RepID=A0A3M2FRK1_9CYAN +--SLQQQIQQLVTRQNLTAGLYFFNLDSGASL-NVGGDEVFPAASTIKFPILVAFFKAVD +EGRVRLHERLTMRPDLIAPEAGTLQQKPNSQYSALEVAELMITISDNTATNMIIDRLEGT +AALNQQFQEWGLENTVIHNLLPDMKGT------NTTSPRDLATLMLKIGQGEILSPRSRD +RLLDIMRRTVT-NTLLPAGLGKGATIAHKTGDIGI-VVGDAGMVDMPNGQRYVAAMMVKR +PYND-PRGSELIRQVSRMVYQAf +>[subseq from] serine hydrolase n=1 Tax=Sphingobium bisphenolivorans TaxID=1335760 RepID=UPI0003A09FEF +--RLMNEFSRFAALTDGTVGIAVRDLSSGEML-SFNGDTLFPMASTYKVAVAGKILALLD +HGQLGLDEQLP---------------RLGRSMPVRALLDMMLTQSDNEATDALVARAGGP +AAVDGWVRALGIKGLRVDSNTAQLLAAFATDPRDTSTPRAMGELLSAIRQGKALKPSSTA +LMLSIMDRCKTGKMRLRAMLPPGTQIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK +DHRGHVIRDRIMAEAARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Tolypothrix sp. PCC 7601 TaxID=1188 RepID=A0A0D6L2M5_9CYAN +--SLKSAVQNLAAANSLTPGVLLVDLDTGSYV-DINSAASFPAASTIKVPILVAFFQDLD +AGKIRLDEMLTMQQSMIAGGSGNMQYKPAGTYSALEVATKMITISDNTATNMLIARLGGI +EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVNMRSRD +RLLDIMRQTER-DNLLPSGLGTGATIAHKTGDIGT-MLADAGLVDIPTGKRYIAAVMVQR +PNND-ARAEKLISGISRAAYQQf +>[subseq from] Beta-lactamase n=1 Tax=Fluoribacter dumoffii TaxID=463 RepID=A0A377GE13_9GAMM +--ELLKKLNAIEKKSNTVMGITAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD +EKKDSLNRVIKMDSRYSVPGSGSLHYLFEKRITLKEILKHTLRNSDNSASDALLQAAKGP +KYVAQRMSALGFKNIFVNRSIMEMFVRFEKDIRDTTTPNDMAKLLVKLYKKQALSESSTN +LLMDIMEKCRTGRSRIRGLLPAHVKVAHKTGTWSYRFVSDVGIITLPNNGHIAIAVYVKS +KSASDYPRSRAIALASRAIYDHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2D8TBN4_9SPHN +--KLLAEFERFAALSDGTVGIAVRDLQTGETQ-SFNGDTLFPMASAYKVGVAGRIFALVD +AGDLRLDDQLALDPALASEGIAWMFSRPGAALSVQRLLELMLQKSDNNATDVLVARAGGP +QAITRFVTGLGVNGLRVDSDTAHLLYSFATEIEDTSTPRAMLDLLSAYESGRALSADSTQ +RLFTIMAHCETGKHRIVGMLPPGTAVAHKTGSLN-GTGNDVGVVRLPDGRRFAVVAFVMK +DGKGHKARDRIIAEAARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Legionella quateirensis TaxID=45072 RepID=A0A378KSP4_9GAMM +--ELTKKISAIEKKSNSIMGITAIYIEKNKVI-THNSTQRFFMASTIKLPIAMAFLHRVD +QKKDSLNRIIKLGLSNSVPGSGTLHHACEKKMSMQQILKYMLTNSDNSASDTILHTVNGP +EYVTKRMYELGFKNIFINRSILEMFMRFENDKRDTTTPDEMAKLLVKLYKKEALSESSTQ +VLINIMEQCRTGRSRIRGLLPGNVKVAHKTGTWAPGFASDVGIITLPNNGHIAIAVYVKS +QAASDYSRSRAIALASRAIYDHf +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1K7B0_9ZZZZ +------------------------------------------------------------ +----------------------VTEKHLTDGMTVRELCSAAITMSDNTAVNLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIA---------- +>[subseq from] Serine hydrolase n=2 Tax=Bacteria TaxID=2 RepID=A0A515LB61_9SPHN +---IEAMVARIADGSNGRIGVYAVDLASGRQV-SVLGDQRFPMASTSKIAIAATFMEGVE +RGRFSLTSEFPLMVPVASAFSSSKAPVVPGKYKAVDLIEMMITRSSNPATDALLAAVGGP +AAVNSWAQRNGIGEFNLTRDIATLVRARSVDVRDSATPQAMVSLLTGLYQGKFLTDRSRQ +VILGAMSRCKTGTRRIPAMLPSGAQVAHKTGSLNN-TSSDIGIINTPDGRAIAVAIYVTG +QG-SRPAREAKIANIARALYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium timonianum TaxID=1805473 RepID=UPI00083B78D9 +---FKKIIETILAHKKADVGVSILTAGTKKEVtQINGNKPLPMLSTFKFPVALAVLHKVE +KGELSLQQKIYIKKEELLEYSPFKDKYPEGNLSLEDCLQWMVVYSDNNLTDILLRLIGGP +DDVQNFINS---KDIVIKNDEEGMHKDWDSQFINTITPNEAIRLLERFYTGKILNKEHTK +WLYTAMLNNATGIKRLKGKLPKDVKVAHRTGTSFTGAINDYGIIELSDKKRIYIAVFVHD +TYETFENSEAIIADIAKAAYDYy +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. HKB08 TaxID=2502843 RepID=UPI001008E662 +---FEKRIAMLADGDKGRIGVAAVDLATGEEI-SILGDQRFPMASTSKIAIAATFMEGVE +QGRWSLSSEFPLLIPVRSAYSSDRAPVRRGKLPAEELIELMITRSSNPATDALLDVVGGP +SAVNDWMRRNGIGEFQLTRDIATLVRATFIDKRDSATPKAMVELLTGLYQGKFLSASSRR +VILGAMERCVTGKRRIPALLPASANVAHKTGSLNN-TSSDIGIIQSPDGRAIAVAIYVTG +QG-TRLNREARIAEIASALYDGy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9JQX3_9BACT +--RLEREMARLAQGAGGAVGVAVTHLETGRKV-ALRGRERFPMASSYKVPIAVRLLERVD +RGELRLDQMVELRAKDLHPGSGTLTDLFNKPLSVRNLLELMLLISDNSATDVCLRLAGGP +ERVMARMREVGIQGIDVNRSTAQLIARFNADRRDTAEPEAMRALLERIWARDLLRPDSAE +LLLDIMRRCRTGGARLRGILPAGTEVAHKTGTIG-GTTNDVGIVTLPDG----------- +----------------------- +>[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=Bacteroides TaxID=816 RepID=A0A5M5NE31_BACOV +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIADISRIVYEY- +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. D2 TaxID=556259 RepID=E5C4M8_9BACE +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIADISRIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SMA0_9BACT +-sELENRIDSLLNCKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDPFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Beta-lactamase n=1 Tax=Streptococcus mitis TaxID=28037 RepID=A0A0K2D1V6_STRMT +-sELENRIGSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYFAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. KY5 TaxID=2011159 RepID=A0A2Z4JW68_9SPHN +--SFEQRIAELADGGRGRIGVAALDLATGESV-SVLGDQLFPMASTSKIAVAAAYLEMVE +QNKYSLTSEFPLLIPIRSASSPAAPVRKGNYMPAIDLIEIMITRSSNPATDALLAAVGGP +EKVNDWMRRQGITDFSIDRDIATLVRANWIDPRDAATPSAMVRLLQGLYRGDFLSDQSRQ +VLLGAMSRTVTGRRRIPANMPDEAVVSHKTGSLNN-TSSDIGIIESPDGRAIAVAIYVTG +QG-TRLNREARIASIARALYDGf +>[subseq from] Beta-lactamase n=1 Tax=Legionella sp. km535 TaxID=2498107 RepID=A0A433K700_9GAMM +--EIAKKIAAIEKKSNSIMGITAIYIEKNKVI-SHNSTKRFFMASTIKLPIAMAFLHRVD +QKKDSLNRIVKLGLSNAVPGSGALHHACERKMSMQQILKYMLANSDNSASDTILHTVNGP +EYVTKRMYELGFKNILINRSILEMFMRFENDKRDTTTPDEMAKLLVKLYKKEALSESSTQ +ILIKIMEQCRTGRSRIKGLLPGNVKVAHKTGTWAPGFASDVGIITLPNNGHIAIAVYVKS +QAASDYSRSRAIAQASRAIYDHf +>[subseq from] serine hydrolase n=1 Tax=Porphyrobacter cryptus TaxID=196588 RepID=UPI0004092F6F +--SLQQRIAELANPALGRIGVAAVDLSTGEEV-MVLGDQLFPMASTSKIAVAAAFLEQVE +RGRYSLTSEFPLLLPVASPSSAKAPVRPGQYMPAIDLIEIMITRSSNPATDALLAAVGGP +AVVTDWMRRHGINEFSINRDIATLVRATTIDPRDAATPRAMVRLLAGLYRGEFLSAESRA +VILGAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGIIETPDGRAIAVAIYVTG +QG-SKAAREERIAAIARALYDGf +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Fremyella diplosiphon NIES-3275 TaxID=1973485 RepID=A0A1Z4MG52_MICDP +--SLKSAVQNLAAANSLTPGVLLVDLDTGSYV-DINSAASFPAASTIKVPILVAFFQDLD +AGKIRLDEMLTMQQSMIAGGSGNMQYKPAGTYSALEVATKMITISDNTATNMLIARLGGI +EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVNMRSRD +RLLDIMRQTER-DNLLPSGLGTGATIAHKTGDIGT-MLADAGLVDIPTGKRYIAAVMVQR +PNND-ARAEKLISGISRAAYQQf +>[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5201 TaxID=2019672 RepID=A0A2N6N240_9CYAN +--SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD +AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI +EALNQRFRSWGLNTTAIRNQLPDLQGT------NTTSPKELGNLMAMVSQGNLLNMTSRD +RILDIMRNTVR-NHLLPTGLGQGASIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR +PNND-PRAEKLIGSISKATYQQf +>[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=A0A494JAI3_9FLAO +---LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMFPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQEFMDS---SSFIIKNDEEGMHKDWDSQFINKITPNSAALLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHD +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium nitrogenifigens DSM 19370 TaxID=983920 RepID=F1Z6N3_9SPHN +--AIQRTVEAIVARARGRVGVAAVDLDGGGQV-LVNGDMPFPMASTAKVAVAATFLAGVE +QGRHRLDQQLPMMMPVAERHSAVAAVRPGPVMTAQQLMELMITRSNNHATDGLIAAVGGI +GAVNSWLSKNGIVGQHLDSTMATLVRAKTIDTHTSSTPRAMAALLAAIDRGGALSPQSRA +VLLDTMTRTSTGKNRMRAGLPEGTIFAHKTGTLS-GVTDDVGIIRLPDGRHLALAVFVAG +PEGH-LIHANMIAQITRALYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Asaia astilbis TaxID=610244 RepID=UPI0009FFD389 +---------RYERASGGRIGAHLFCPQTGLAI-SWRGEERFLMCSSFKASLAACVLKRCE +GDEDDLTRRLSFVDSDFKTWAPVARQNRDAGLSLAALCAGAVSMSDNVCANMLLRHIGGP +AALTKFWRDSGDDITRLDAYEPELNRPSADPEANTTSPIAMARTLHRLIHGTLLRPHSAA +LLRDWMTSCVTGTHRLRAGLPLTWAAGDKTGNNGKDISADIAFASPANSGSVIMAAYTAG +GKPDEARFRSVFHDLGAL----- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium TaxID=1978525 RepID=A0A4V1SSA7_9SPHN +---LEATIARIADGSAGRIGVYAVDLASGREV-SVLGDQRFPMASTSKIAIAATFMEGVE +RGRFTLTSEFPLMVPVASAFSSSKAPVVPGKYKAVDLIEMMITRSNNQATDGLLAAVGGP +AAVNDWARRNGIAEYNLTRDIATLVRARTVDIRDSATPEAMVRLLSGLYQGKFLAESSRK +VILGAMSRCRTGTHRMRAMLPDEARVAHKTGTLSN-TASDVGIINTPDGRAIAVAIYVTG +QG-SRAARDAKIASIARALYDGy +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. Leaf26 TaxID=1735693 RepID=A0A0Q4ITK4_9SPHN +--KLLAEFTRFATLSDGTVGVAVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRIFALVD +AGEVRLDDQLALDPALASEGIAWMFNRPGATLSVDRLLELMLQKSDNNATDVLVARAGGP +QAITAFVQKLGVTGLRVDSDTAHLLYAFAMEPQDTATPTAMLDLITAYESGRALSAASTQ +RLFTIMAHCETGKARIIGMLPPGTAVAHKTGSLN-GTGNDVGIVRLPDGRRFAIVAFVMK +DSKGHVSRDRIIAEASRAAYDYf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A3E5HQM2_BACOV +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTI-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLETQLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP +DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIADISRIVYEY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Parabacteroides timonensis TaxID=1871013 RepID=UPI00094EF2C4 +-eQLKANIQEIIKDKKARIGVGII-LNGKDTV-TINNEDPYPMMSVFKFHQALAVLNYLQ +QNNLPLDTPIRIEKEDIIEYSPLRDKYPQGNLPISELLKYIIQLSDNIACDVLFKYIGGP +SVADKYIRSLGIQQFSIVITEDDMHQDLSACYLNWSTPLEATRLLEILLTRPLFKDEYQE +FLKNIMIECETGKDRLPQLLKTDAVIGHKTGTSDKGGTNDIGFVLLPNGSRYTVAVFIKD +SNESMETNAKIIASISEVIYKYf +>[subseq from] Beta-lactamase class A n=2 Tax=Bosea sp. 124 TaxID=2135642 RepID=A0A2T4YEM7_9BRAD +-aKLDREIVAIERQSKGRLGVALLDLKDSRTW-SHRGTESFPMQSVFKWPLAIAVLQAVE +AGRFKLDEKITIRRSEFSLHSPLAKAFEGESYPLRELIALAAGESDNTAADILMREIGGP +RVVRAMLAAGGIQGITVDRYERQFQPTALKDRRDSATPEASVLFVEAQARGNWLRGPAHN +ALIDIVTETKSGADRIRAGLPEGARFAHKTGLGLNHATNDIGLVNLPNGRVFAIAVYLAG +STADARTREAAHAAVAKLAVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI000C999D6E +-----SAVRELAHSLKARVGMAAEMLDTEETV-MVGDEAAYPMQSVVKFVLALSVLKRVD +QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP +QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQS +VLWNIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD +SKDSESACDRVIASMARWLCL-- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter jejuensis TaxID=795812 RepID=UPI00136F2C64 +--SFERRIAQLADGSKGRIGVAAVDLSSGEQI-SILGNQRFPMASTSKIAVAATFLEGVE +QGRWSLTSEFPLMIPIRSKYSSRAAPVRKGNMPAIDLIEIMITRSSNPATDALLKVVGGP +NAVNGWARRNGIREFSIDRDIATLVRVSYIDRRDSATPRAMVDLLAGLYQGKFLSRESRR +VLMGAMSRTRTGKRRIPAMIPGEAEVLHKTGSLNN-TSSDIGIIRTPDGRAFAVAIYVTG +QG-TRRNREAKIASIARALYDGy +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=A0A0K9YPY6_9BACL +--SLEQKLLDVISDVSGTFGVAVKHLQTGEAA-SINGDQLFQLASTFKIPILAALYRDVE +AGKLSLEDRIKITEEDMVPGSGVLQEHLGVEVTVKDLAMLMIIVSDNLATDQLLKLV-GT +DQVTAYMRELGLADVHIHHSCWDLLSVFQADPRNVGTPVDMAKLVELIALKELISEQACD +GMLDILFRQQF-NSRLPYMLPGKAKVAHKTGTLSS-VVNDVGVVYLPDNGAFSIAVLSKD +NP-SMEEGERTIGRIARAAYDHf +>[subseq from] Beta-lactamase n=2 Tax=Legionella moravica TaxID=39962 RepID=A0A378JTF7_9GAMM +--EIAKKIAAIEKKSNSIMGITAIYIEKNKVV-SHNSTKRFFMASTIKLPIAMAFLHRVD +QKKDSLNRIVKLGLSNAVPGSGALHHACERKMSMQQILKYMLANSDNSASDTILHTVNGP +EYVTKRMYELGFKNILINRSILEMFMRFENDKRDTTTPDEMAKLLVKLYKKEALSESSTQ +ILINIMEQCRTGRSRIKGLLPGNVKVAHKTGTWAPGFASDVGIITLPNNGHIAIAVYVKS +QAASDYSRSRAIAQASRAIYDHf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Pararcticibacter amylolyticus TaxID=2173175 RepID=A0A2U2PIZ6_9SPHI +-tDLKQRVEQIISTKKADIGVSIQSSGTGETM-DIRGNQHYPMISIFKFHIALAVLNKVD +NKQLSLKQKIFVRKDELLEWSPFREKYPKGDITLEEALRWTVSHSDNNLGDLLIRLAGGV +RAISNFL---NDPSFIIKNNEEEMHKSWDAQFLNTTTPNFSTRLLDDFYNGKILSRKSTK +LLYEMLVETSVGLNRIKGKLPKETEVAHRTGSSFTGAINDIGIVKLPDGNYFIISVFVHN +TTERYKDGEEIIADIAKAAWDYy +>[subseq from] Penicillin binidng protein PbpA n=2 Tax=Thermosynechococcus sp. NK55a TaxID=1394889 RepID=V5V7C0_9CYAN +--SLQQQIQQLVTRQNLTAGLYFFNLDSGASL-NVGGDEVFPAASTIKFPILVAFFKAVD +EGRVRLHERLTMRPDLIAPEAGTLQQKPNSQYSALEVAELMITISDNTATNMIIDRLEGT +AALNQQFQEWGLENTVIHNLLPDMKGT------NTTSPRDLATLMLKVGQGEILSPRSRD +RLLDIMRRTVT-NTLLPAGLGKGATIAHKTGDIGI-VVGDAGMVDMPNGQRYVAAMMVKR +PYND-PRGSELIRQVSRMVYQAf +>[subseq from] class A beta-lactamase n=1 Tax=Moraxella sp. VT-16-12 TaxID=2014877 RepID=UPI000B7E2256 +-nKLNEILPRWEKRLNAKIGMAIIN-DDGQIN-SYRKEDYFPVNSTIKAFIVAHVLFLVD +KGKLDLTQSILIKKSDLIEYSPVCQTFFNEKITISELCEATTTLSDNAAANILLNHLGGL +MAFNQFLKDIGADVV-LSHNEPLLNHAHYGETYNTAKPNSYAQSLKDIITKDILSNQSKN +QLLTWLINDKVADDLLRKHLPKNWRIGDKTGTGSE-SKNIVAVIWNAQNKPYFISLFITQ +PNDGKTQKSIAIANIGQ------ +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. CAG:754 TaxID=1262750 RepID=R6D3V4_9BACE +--SLETQLKEAIKDKKAEIGIAVI-IDGKDTV-TVNNDTHYPLMSVFKFHQALALADYMG +KRNQSLDTLLTVEKSDLKPYSPLRDKYPEGGMSIAELLKYTLQQSDNNACDILFHYQGGP +DSANKYIRSLGIQDCEITHTENDMHEDLDFCYSNWSTPLAAAKLLEIFRREPLFAKEYKD +FIYQTMVECQTGQDRLVALLDNGVIVGHKTGTGDRNGCNDIGFVVLPDGHTYSIAVFVKD +SEESSPENSKIIADVSHIVYEY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A650AIB5_ECOLX +------------------------------------------------------------ +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAFPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDI------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. LD22 TaxID=2650748 RepID=UPI00124BDFD7 +-----------ASRLGGTLGVVAHDLGTGERA-EVNAERRFTSASVIKIAIMATVLAEAE +AGRRSLDDRLPAPPDARVPGSGVIKDLADAAFSVRDLVTLMIIVSDNTATNLLIDLV-GR +DAVNAWCARHGLHGTVLARVMMDAAA-RERGEENLMTPADVAALLTGLVRGEMLGEASTA +FALDVLSRQQL-NDRLPRHLPPGVTLAHKTGELA-AVCHDAGIVLPKDRDPIVLVAMTEG +ID-SEPEAGTLIADTGRAVYT-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis granuli TaxID=267128 RepID=A0A0X8R5W0_9SPHN +---LDDRIASLWRAFPGKTGIAIQRIDGEWAL-AQRGGDLFPQQSVSKLWVALTVLDAVD +AGRISLDQMVRIGPEDLTLHQPLAARVRAEGMSVRDLIETAITHSDNTANDSLLRTVGGP +KAVRAFIADKGLGAIRFGPGERLLQSNYLADPIDGASPAAIASALTRLARGTLLSPASTE +YLLGVMSRTRSGPKRLKAGLPDGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGN +TTASIPARMALMQAVSGAVAE-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. HIX TaxID=1759074 RepID=A0A0W1EHE4_9SPHN +---LDDRLFQIWKAFPGKTGIAVQRIDGEWAL-TQRGGELFPQQSVSKLWVTLAVLDAVD +NGRLRLDQNVRIGPEDLTLHQPVAARVQSQGMTVRELIETAITQSDNTANDSLLRTVGGP +DAVRRFIDRKDLGAIRFGPGERLLQAAYRADPPDGASPAAIANALTRLARGTLLSPESTQ +YLLGVMTRTKSGPQRLKAGLPAGWTFLHKTGTGQTVGYNDIGIATAPDGTRYAIVVLMGE +ASSPVPARMATMQSVSRAVAE-- +>[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. LD22 TaxID=2650748 RepID=UPI00136F0D00 +-----------ASRLGGTLGVVAHDLGTGERA-EVNAERRFTSASVIKIAIMATVLAEAE +AGRRSLDDRLPAPPDARVPGSGVIKDLADAAFSVRDLVTLMIIVSDNTATNLLIDLV-GR +DAVNAWCARHGLHGTVLARVMMDAAA-RERGEENLMTPADVAALLTGLVRGEMLGEASTA +FALDVLSRQQL-NDRLPRHLPPGVTLAHKTGELA-AVCHDAGIVLPKDRDPIVLVAMTEG +ID-SEPEAGTLIADTGRAVYT-- +>[subseq from] Beta-lactamase n=2 Tax=Akkermansia TaxID=239934 RepID=A0A139TSY4_9BACT +-----ASIREIVRPLKAHVGVSAVMLDTGESV-SVGDEAFYPMQSVYKFPLALSVLKRVD +QGVLDLDQKVQVTRDQLPEWSPLRDRFPQGGFPLKELLRFSVQESDNNACDILFSLIGGP +KAVQKDLKKWGVENMNVKYTEADTHRNNEWQYSNSARPSAMTSLFRRFDEGKILKKDTQL +FLWDMMASCATGAERLKGLLPKEYVVAHKTGTGGVSAINDAGIIVLPGGRRMAVTVFVMN +SKDSPAVCEGTIASVARWLCTEw +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A5M6BIX5_9BACE +--SLEAQLKEAIKDRKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA +KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP +DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD +FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEESFAENSKIIADISRIVYEY- +>[subseq from] Peptidoglycan glycosyltransferase n=2 Tax=Nostocales TaxID=1161 RepID=A0A1Z4N775_9CYAN +--SLKTAVQNLAAANSLTPGVLLVDLDTGSYV-DINSAASFPAASTIKVPILVAFFQDLD +AGKIRLDEMLTMQQSMIAGGSGNMQYKPAGTYSALEVATKMITISDNTATNMLIARLGGI +EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVNMRSRD +RLLDIMRQTER-DNLLPSGLGTGATIAHKTGDIGT-MLADAGLVDIPTGKRYIAAVMVQR +PNND-ARAEKLISGISRAAYQQf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis italica TaxID=1129133 RepID=UPI00143A0A18 +---LNDRIYDLWRTFPGKTGIAVQRIDGEWKL-SQRGDELFPQQSVSKLWVALTVLDAID +QGRLTFDQRVRIGPEDLTLYQPLAARVRAEGMSVRDLIETAITKSDNTANDSLLRTVGGP +DAVRAFFDKKDLGAIRFGPGERLLQAAYLANPPDGASPEAIASALTRLARGTLLSPDSTE +YLLDVMSRTRSGPRRLKAGLPAGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGD +TNASVPARMELMQAVSGAVADY- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1I7H6_9ZZZZ +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATR---------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SP34_9BACT +-sELENRIDSLRNGRKAPVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Culturomica massiliensis TaxID=1841857 RepID=UPI0008398E62 +--TLQKQIRSILKDKKAMIGVAVLY-NGKITV-SVNDDQGYAMLSTFKFPLALAVCDYLD +RQKLPLETEIYVSKADLHPYSPLRDKQPEGDISIKELLRYCVSLSDNNACDILIRYIGGI +ERLQQYIADLGFPDMVIVATETQMHQQTGNQALNRTRPSAAVLLFEQFLQKKLLSATYQD +FLEQILIETTTGANKLKGLLPSGTLVGHKTGSSDRNGDNDMGFVYLPNGNYFVIAVFIMD +SMEDDDTNASIIARISRTVYDHy +>[subseq from] Beta-lactamase n=1 Tax=Moraxella osloensis TaxID=34062 RepID=A0A2D2LXA5_9GAMM +-------LPSWENKLNAKIGMAVITASNNELA-SYRGNDFFPFNSTIKAFIGAYILHLVD +KGQLDLAHTLQIKATDLLEYAPQSKKFFEANISIAELSEAMITVSDNTASNLLLDTTGGL +KPFNDFLHQIGNSEVILAHNEPLLNRSHYGEKIDTAKPIAYTQALKNILMGNILSEQSKK +LLLTWLINDKVGDSLLRKHLPNDWQIGDKTGAGDE-SRNIVAIIWNSQKEAYFVSLFITQ +PYKSNNQKSVAIAEIGRAIYS-- +>[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI0009E0AE99 +---------QLAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD +QGAMNLEQIIRIRQEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP +QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQS +VLWNIMAGCSTGPERLKGLLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD +SKDSESACDRVIASMARWLCL-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis granuli TaxID=267128 RepID=UPI0009586E5A +---LDDRIASLWRAFPGKTGIAIQRVDGEWAL-AQRGGDLFPQQSVSKLWVALTVLDAVD +AGRISLDQMVRIGPEDLTLHQPLAARVRAEGMSVRDLIETAITHSDNTANDSLLRTVGGP +KAVRAFIADKGLGAIRFGPGERLLQSNYLADPIDGASPAAIASALTRLARGTLLSPASTE +YLLGVMSRTRSGPKRLKAGLPDGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGN +TTASIPARMALMQAVSGAVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis granuli TaxID=267128 RepID=UPI00082D43F7 +---LDDRIASLWRAFPGKTGIAIQRVDGEWAL-AQRGGDLFPQQSVSKLWVALTVLDAVD +AGRISLDQMVRIGPEDLTLHQPLAARVRAEGMSVRDLIETAITHSDNTANDSLLRTVGGP +KAVRAFIADKGLGAIRFGPGERLLQSNYLADPIDGASPAAIASALTRLARGTLLSPASTE +YLLGVMSRTRSGPKRLKAGLPDGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGN +TTASIPARMALMQAVSGAVAE-- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Sphingopyxis TaxID=2614943 RepID=A0A1E4JR26_9SPHN +---LDDRIASLWRAFPGKTGIAIQRVDGEWAL-AQRGGDLFPQQSVSKLWVALTVLDAVD +AGRISLDQMVRIGPEDLTLHQPLAARVRAEGMSVRDLIETAITHSDNTANDSLLRTVGGP +KAVRAFIADKGLGAIRFGPGERLLQSNYLADPIDGASPAAIASALTRLARGTLLSPASTE +YLLGVMSRTRSGPKRLKAGLPDGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGN +TTASIPARMALMQAVSGAVAE-- +>[subseq from] class A beta-lactamase n=2 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000D00BA33 +hdALQATLERFAQAAPGTLGVVVLDLERPARW-QVNGTLPFPMMSVFKAPLGATVLDLSE +QGRLPLGHRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP +VVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR +RLLGLLRDQTQ-PRRLRAGLPPGVTFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA +SRASRAERERLFADLARAVAS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A166W7W3_ECOLX +-----------------------------------------------------AVLLRSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTN--------------------- +----------------------- +>[subseq from] Putative beta-lactamase n=1 Tax=Bacteroides sp. 2_2_4 TaxID=469590 RepID=C3QTD3_9BACE +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQRQSLETQLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP +DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIADISRIVYEY- +>[subseq from] class A beta-lactamase n=1 Tax=Dyella sp. C9 TaxID=2202154 RepID=UPI000DEFAFDC +-----RVVDAYAARAPGTLGVAVLDLKTGATA-GVNADKPFPMMSVFKAPVAAAVLSRVD +AGTLSLDQRVTIHRSDVLSGSAVPARFRGEQFTVEQLLKAAVSESDNTAVDALLKVV-RP +DEVTAFLHAHGIDGLRVDQDEAGVAQAFLDDPRNRSTPDAAVMFLRKLGGGELLSPASTQ +HLLGLMAAQTI-PNRLRAGLPQGVRFADKTGTSGTAAYNDIGIATWPDGRVLIVAAFLLD +SPATPQARDALFATFARD----- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A414FKE5_9BACE +--SLETQLKEAIKDKKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALANYMA +KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP +DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKN +FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEESFAENSKIIADISRIVYEY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=UPI000E7EDD4F +--SLETQLKEAIKDRKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA +KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP +DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD +FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEESFAENSKIIADISRIVYEY- +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=5 Tax=Bacteroides TaxID=816 RepID=A0A1Y4V0K2_9BACE +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQRQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP +NAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMIECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIADISRIVYEY- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=UPI000CCC49D2 +--SLEQKLLEIAQGASGTFGVTVKHLQTGETT-SINGNELFQLASTFKIPILATLYRDVE +AGKLSLDDRFKISEEDLVPGSGVLQEHLGVEVTVKDLAMLMIIVSDNLATDRLLKLV-GT +EQVNAYMRELGLENTHIHHSCWDLLSVFQADPRNAATSEDMAKLVELIAKKQVVSEQACD +GMLDILFRQQF-NSRLPYMLPAKTKVAHKTGTLSD-CVNDVGVIYLPDKGSFAISVLSKN +NP-TMEEGERTIGRLARAAYDHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=B2CD48_ECOLX +------------------------------------------------VLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGCFL---------------------------------- +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. Leaf180 TaxID=1736289 RepID=A0A0Q5QE39_9FLAO +---TQMDVSKILYDKKATVAVSVLGFEKEYSF-DKNGDAKLPLLSVFKFHIAATVLHLVD +EGELALDQKVILTDAEMIPWSPIREKFPKGDLTLAELLEYTVAQSDNNGCDKLLKLIGGT +ETVQKFMDSKGVKDFQIKVNEEAMQQDRKNMYENFSSTKSAVRLLKSFYENKIISRKSTE +FLMNTMLSTSTGANKLKGWLPKNVRVAHKTGSSGKDAENDMGIVTLPNGKHYAIAVLISD +STETAEVNCGIIADISKVFYD-- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas sp. (strain SKA58) TaxID=314266 RepID=Q1N8Q5_SPHSS +--KLLGEFERFATLSDGTVGIAVRDLQTGETQ-AINGDTLFPMASAYKVAVAGRIFALID +AGDVRLDDQLALDPALASEGIAWMFSRPGASLSVQRLLELMLQKSDNNATDVLVARAGGP +AAITHFVKGLGVDGLRVDSDTAHLLYAFATEIEDTSTPRAMLDLLTAYESGKALSADSTQ +RLFTIMAHCETGKGRIIGMLPPGTAVAHKTGSLN-GTGNDVGVVRLPDGRRFAVVAFVMK +DSKGHKSRDRIIAEAARAAYDYf +>[subseq from] serine hydrolase n=1 Tax=unclassified Novosphingobium TaxID=2644732 RepID=UPI001358CD9F +-----QQLAAVANASQGRIGVAAMDLTSGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD +KGKWSLTSEFPLMVPVGSASSAVAPVRAGEYMTASRLIELMITRSNNYATDALLKVVGGP +KAVNAWVGRAGIDDWHIDRDIATLVRARVVDTRDSATPYAMVQLLSGIYQGKWLSPSSRS +VILGAMSRCVTGKRRIPAGLPEGAQVSHKTGSLNN-TSSDVGIVQTPDGRVFAVAIYVTG +QG-GRPGRESRIASIARTVYNGy +>[subseq from] class A beta-lactamase n=1 Tax=Algoriphagus resistens TaxID=1750590 RepID=UPI00071681C3 +-nSLYSTIQQISDTSSGQLGVSILHLESGEKV-SLNGDKKFPMQSVYKFPIAMAVLQEID +KEKFSLDDSIAIHKSEYIPHSPIRDQFPEGVMTLRDILAYNVSHSDGTACDVLLRILGGT +EKAEKKIHGLGIKDIAISTTEMVQVAHDTIQYQNWSTPDAMNDLLVVFFKGKDLSENSRQ +FLLKLMSSNPWFDRRIKGLLPKETPLVHKTGTAATRATNDVGIITLPDQSHLVISVFISD +SYDSQSKRESIIASVSKAAFDHw +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium barchaimii LL02 TaxID=1114963 RepID=A0A0J7XND4_9SPHN +-----QQLAAVANASQGRIGVAAMDLTSGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD +KGKWTLTSEFPLMVPVGSASSAVAPVRAGEYMSASRLLELMITRSNNYATDALLKVVGGP +KAVNAWVERAGIDDWHIDRDIATLVRARVVDTRDSATPYAMVQLLSGIYQGKWLSPSSRS +ALLGAMSRCVTGKRRIPAGIPEGAQVSHKTGSLNN-TSSDVGIVQTPDGRVFAIAIYVTG +QG-GRPGRESRIASIARTVYNGy +>[subseq from] Beta-lactamase n=1 Tax=Acetobacteraceae bacterium AT-5844 TaxID=1054213 RepID=H0A7W7_9PROT +--NAEAEIRRIAAYCQGEVGIAARHLGTGAEL-SVQGEARFPMASTIKMTLVLTILDLAR +QGRLALTDMVSIRPEEMTPLGPLGGEFPHDGLSVLNLLEATITRSDNSATDVLFRVAGGT +AAVQAHMHAIGLRDIEVKRTMREALCDYGHPNRDHATPRAMLALLARLWAGEGIEPAARD +TILAMMARTSTGATRIRARLPAGIAVAHKTGSGT-GTANDLGFLTLPNEGTVALVAYVKG +SPLPVEARDAVLADTARLVLDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Odoribacter sp. OF09-27XD TaxID=2293112 RepID=UPI000E55DE4A +--TLQKQIRSILKDKKAMIGVAVLY-NGKITV-SVNDDQGYAMLSTFKFPLALAVCDYLD +RQKLPLETEIYVSKADLHPYSPLRDKQPEGDISIKELLRYCVSLSDNNACDILIRYIGGI +ERLQQYIADLGFPDMVIVATETQMHQQTGNQVLNRTRPSAAVLLFEQFLQKKLLSATYQD +FLEQILIETTTGANKLKGLLPSGTLVGHKTGSSDRNGDNDMGFVYLPNGNYFVIAVFIMD +SMEDDDTNASIIARISRTVYDHy +>[subseq from] Class A beta-lactamase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A525J8T6_9CAUL +-kRLNTEVAAIAARAPGVLGFGLMNLESGEFW-VRLGDRTFPMQSVFKLPLGTAVLSEVD +AGRLSLGETLTIKPEDLSPWSPIADAWPGRAYTVQELLEAAVSNSDNTAADLLMKRIGGP +GAISSWLQGKNVTEIRVDRYEREIQPAYMADPRDSATPEGMLGFLRKLDEGSLISPASTA +RLLTIMIGTPRGADRLKAGLPKDARFAHKMGTSGTAAFNDVSIFTLADRRSYAICAFLTG +STASDTERAALFAQLGHTAA--- +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter epoxidivorans TaxID=361183 RepID=A0A0M5KZ77_9SPHN +--SFERRIAQLADGDRGRIGVAAIDLATGEEV-AILGDQLFPMASTSKIAIAATYLELVE +KGKYSLTSEFPLMIPVSSARFSSSKAPVRKGMQAIDLIEIMITRSSNPATDALLAAVGGP +DKVNDWVRRQGIKEFSIDRDIATLVRAYYIDKRDAATPRAMVELLRGFYQGKYLSADSRR +VLLGAMSRTRTGKRRIVANMPSDARVSHKTGSLNN-TSSDIGIIEAPDGRAIAVAIYVTG +QG-SRLERENRIASIARALYDGf +>[subseq from] Class A beta-lactamase, subclass A2 n=3 Tax=unclassified Bacteroides TaxID=2646097 RepID=A0A412BVG8_9BACE +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTI-TVNNDIHYPLMSVFKFHQALALADYMG +KQRQSLETRLAIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP +DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIADISRIVYEY- +>[subseq from] class A beta-lactamase n=1 Tax=Phenylobacterium immobile TaxID=21 RepID=UPI000B870DF0 +--ALNRAAEDISRRVPGVLGAGLMNLENGQSW-AFNGDRPFPMQSVFKLPLAAAVLAEIE +AGRLTLDERLVVRPEDLSPYSPIADAWPGRAYTVAEMLNAAVRDSDNTAADMLMRRIGGP +GAVTAWLVDKGVTELRIDRYERQLQTRYLSDPRDTATPRGMLDFLYKLDDGLIIGPVVRE +RLFAMMTGGRV-TSRLAAAMPAGASLLHKTGSSWNAATNDVGLITLADGRRYAAAVFLSG +ASLDDDARDAAIAELGRGMI--- +>[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A5M5LYK7_BACOV +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP +DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPNVYKD +FIFQTMVECQTGQDRLIALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIADISRIVYEY- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. YG1 TaxID=2082188 RepID=A0A2Z6AFT8_9SPHN +--KLLAEFTRFSTLSDGTVGVAVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRIFALVD +AGEVQLDDQLALDPALASEGIAWMFNRPGATLSVDRLLELMLQKSDNNATDVLVARAGGP +QAITAFVTKLGVTGLRVDSDTAHLLYAFAMEPQDTATPTAMLDLITAYESGRALSAASTQ +RLFTIMAHCETGKARIVGMLPPGTAVAHKTGSLN-GTGNDVGIVRLPDGRRFAVVAFVMK +DSKGHVSRDRIIAEASRAAYDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A174WVN6_9BACE +--SLETQLKEAIKDRKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA +KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP +DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD +FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEESFAENSKIIADISRIVYEY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=C3VJU6_STAAU +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKK +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQA--------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonadales bacterium CG12_big_fil_rev_8_21_14_0_65_65_10 TaxID=1974094 RepID=A0A2M7HJI6_9SPHN +--NLGARIAAIADGSRGRIGVAAMDLTTGQTL-GVLDDQFFPLASTSKIAVAATFLEGVE +QGKWSLTSEFPLLWPLRSKSTRVAPVREGKYLPASELIELMITRSSNPATDALLRVVGGP +DAVNAWMRRNGISEFSIDRDIATLVRAIKVDRRDAATPRAMIKLLAMLHNGDVLTPVHRR +VILGAMERCRTGTRRIPALMPAGATVAHKTGSLNN-TSSDIGFITAPDGHTYAVAIYVTG +QG-SRSNRERRIAEIARELLDGy +>[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. CH25 TaxID=713559 RepID=A0A4Q1FU20_9FLAO +--EFKKIIETILANKKAEVGVSIITSGTKKEVtQINGNKPLPMLSTFKFPVALAVLHKVE +KGELSLQQKIYIKKEELLAYSPFRDKYPEGNLTLEDCIHWMMVYSDNNLTDILLRLIGGP +DYVQNFINS---KDIVIKNDEEGMHKDWDSQFINTITPNEAIRLLKEFYTGKILNKEHTK +WLYTAMLNNATGVKRLKGKLPKDIKVAHRTGTSFTGAVNNYGIIELSDKKRIYIAVFVHD +TYETFENSEAIIADIAKAAYDYy +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter odishensis TaxID=1155476 RepID=UPI000E716866 +---LERRIAQIANGRDGRIGVAAIDLATGEQV-SVLGDQLFPMASTSKIAIAATFLEGVD +QGRWSLTSEFPLLWAVRSQSTRVAPVREGEYLPASQLIDLMITRSSNPATDALLAAVGGP +AAVNDWARRAGLSGFSLDRDIATLVRTYHIDPRDAATPETMVRLLAGIYQGEWLSAESRD +VILNAMERTRTGRNRIRGMMPAGVTVSHKTGTLNR-MAGDIGIVEMPDGRAIAMAIFVTG +QSASRRLRDARIASIARALYDGy +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SN46_9BACT +--ELENRIDSPLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Uncharacterized protein n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=A0A1T3DZQ9_9FLAO +--SLINKINTITENKKAIIAISVLGFENHFKY-NKNSEKKLPMQSVFKFHIACAVLDWVD +KGKLSLDQKITLNKSNLLEWSPLRKKYPNGNVPLSEIIKQTVAFSDNNGCDILLKLIGGT +QTVQKFMDSKHINNFQIVFNEQQMHKDWNAQYQNYTTTASAAKLLKKFYDMKLLSKESTT +FLMNIMLATTTSLNKMVEQLPSKTPVARKTGASGTGAENEIGIITLPNGQHYALAIFVSD +STEPSMVNLRLISDISKAVWDHf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SS25_9BACT +--DLTSDIQEVIKGKKAQVGVAVLY--KDDAF-TANNDDQYPLMSVFKFHIALAVLKKME +KEGIPLTAVVTLGPSDIDTWSPMYKKYKSKKLSYGDLINYMVSQSDNNACNWLINFVGGI +QNVNDFIKNLGIDRIQLIETEKSMEQDIRKTYNNWSTPLSVAQLLRKVYTEKVLSDEHFA +FLEKAMLASASGKDKFRAGLPKEVEVGHKTGMSYRTCDADVGVIYMPGGEKCYLAVLVKD +SKESDAANAKIMADIAKKVYSHy +>[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. B8 TaxID=95611 RepID=UPI0003B3DCDA +------------------------------------------------------------ +---ADLDTFVHFGRDDLLAYAPITSRSVDSGMTVRELIDAPLRFSDNTAANLLVERLGGP +ARVEEYLRSIGDRTTTVDRVEPDLNAATPGDPRDTATPEQFAVDLRRVVLGTVLGRSDRT +LLRDTMLDNTTGAATVRAGVDSAWPVADKTGTGEFGVRNDIAVVYPAGRAPIVVVVMTRK +DTPHAATDDALVAAATRTAV--- +>[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=X5KBF1_9FLAO +---LKKTLESIISGKKATVGVSIMDPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQGFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNSAALLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 106C TaxID=1932667 RepID=A0A252E276_9NOSO +--SLKTAVQNLAAANNLTPGVLLVDLDTGAYV-DVNSAASFPAASTIKVPILVAFFQDLD +AGKIRLDEMLTMQQQMIAGGSGNMQYKPAGTYTALEVATKMITISDNTATNMLIARLGGI +EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLLAMVNQGNLVSMRSRD +RLLDIMRHTER-DTLLPSGLGAGASIAHKTGDIGT-MLADAGLVDISTGKRYIAAVMVQR +PNND-PRAEKLISAISRAAYQQf +>[subseq from] Beta-lactamase n=1 Tax=Scytonema tolypothrichoides VB-61278 TaxID=1233231 RepID=A0A0C2QY42_9CYAN +--TLQRKLEAVAKESDGRVGICAEEIKSGVIT-CVNGDQRFSLQSVMKLVVAAAVMDAID +RGQMRLEDVVTVRKNDLSLVQPIADLVAERGTTVADLISGAVIESDSAATDLLFARVGGA +EGIRTFLKTKRISGLSVDRDEKHLQTAYLKDKRDTATPRGMVTFLSALASGKLLSVKSTA +HLLKVMQATVTFPDRLKAGVPEGWTLGHKTGTSLTAVTNDVGILTAPDGGTISVAVFVAE +SRRSSKERAKVIAATAKTITSSy +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter seohaensis TaxID=266951 RepID=UPI000C223CBF +-nALEQTIAELADGSNGRIGVAAVDLSTGKTV-SVLGDQLFPMASTSKIAVAATFLEGVE +KGKWSLTSEFPLLLPRRSASSPRAPVYEGEYMKAIDLIEIMITRSSNPATDALLRVVGGP +EAVNDWMRRQGIEEFSIDRDIATLVRAQHIDRRDAATPNAILELLSGLYQGKYLSAESRR +VLLGAMSRTRTGKRRIPALMPASVKVSHKTGSLNN-TSSDVGILETSDGRAVAVAIYVTG +QG-SRLNREAKIAQIARALHDGy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0G3FFI5_ECOLX +------------------------------------------------------------ +---------------------------------LAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLAS--------- +>[subseq from] Beta-lactamase n=1 Tax=Aureicoccus marinus TaxID=754435 RepID=A0A2S7TA23_9FLAO +--RLLDQIAAVDKNLDGQLGFSVLHLESGQEI-SHFGNKRFPMQSVYKFPIALVMLQAVD +RGEFSLDQMVEISPSEYIPHSPLRDRFPRGTMSIKELLRYNISESDGTACDVLLRLLGGT +KETEKKLHALGITDMAIATTEMVQMKNDTIQYQNWATPRGMNQLLKVFHQGEVLSEPSGN +LLKEFMSISTWFDRRLKGKLPPGTKLIHKTGTSNNRATNDVGIIELPNGEHLAVSAFIMD +SRDQHQERENAIAQAARLAYNFw +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Termitarium-T10T-6 TaxID=1839775 RepID=A0A1C4TP63_9ACTN +------DFEKLEREFDARLGVYAIDTGTGREV-THNDRDRFAYNSTFKALQAAVVLSTYS +--LDGMDKRVAYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP +GGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA +QLTTWLRTNTTGDAV--------------------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Nostoc sp. 106C TaxID=1932667 RepID=UPI000A39197A +--SLKTAVQNLAAANNLTPGVLLVDLDTGAYV-DVNSAASFPAASTIKVPILVAFFQDLD +AGKIRLDEMLTMQQQMIAGGSGNMQYKPAGTYTALEVATKMITISDNTATNMLIARLGGI +EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLLAMVNQGNLVSMRSRD +RLLDIMRHTER-DTLLPSGLGAGASIAHKTGDIGT-MLADAGLVDISTGKRYIAAVMVQR +PNND-PRAEKLISAISRAAYQQf +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingobacterium siyangense TaxID=459529 RepID=A0A420G0H7_9SPHI +-nSLRKELHQIIATKNATVGISMKGIEIKDTL-SINGHLNAPLMSVFKFHIALATLNLVD +QGKLSLSQKFFIKKEDLHAWSPIRDEFPNGNLTLDQLLRYTVSHSDNNGCDILLDLIGGP +ETVQKFIHKQGIKDFTIKVNEQEMR-IWENLYINTTTPLASTELLEKFCAGQVLEKNTTN +YLYQLMVECSRGLTWMKAGLPEGTELAHRTGISDRAAMNDVGIFKLPNGNHIVLSVYLKD +ITEEREVTEKIIADITKSIWNYy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0G3FHC6_ECOLX +------------------------------------------------------------ +---------------------------------LAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAESRRDVLAS--------- +>[subseq from] Beta-lactamase n=1 Tax=Legionella anisa TaxID=28082 RepID=A0A2Z3KSN3_9GAMM +--ELIKKIKDIEKKSNTVMGVTAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD +EKKDSLNRVIKMDSRNSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP +RYVAKRMNALGFKNISINRSIMEMFIRFEKDIRDTTTPDDMAKLLVKLYKKQALSESSTD +LLMKIMEQCRTGRSRIKGLLPANVKVAHKTGTWSYRFVSDVGIITLPNNGHIAIAVYVKS +KSASDYPRSRAIALASRAIYDHf +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Calothrix sp. NIES-2098 TaxID=1954171 RepID=A0A1Z4FQV5_9CYAN +--SLKTAVQNLVAANNLTPGVLLVDLDTGAYV-DVNSAASFPAASTIKIPILVAFFQDLD +AGKIRLDEMLTMQQPMIAGGSGNMQYKPAGTFTALEVVTKMITISDNTATNMLIARLGGI +EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLLAMVNQGNLVNMRSRD +RLLDIMRQTQR-DNLLPSGLGAGASIAHKTGDIGT-MLADAGLVDIPTGKRYIASVMVQR +PNND-ARAEKLISAISRAAYQQf +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroides caccae CAG:21 TaxID=1263037 RepID=R5UU18_9BACE +--SLETQLKEAIKDKKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA +KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFGYQGGP +DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYQD +FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEESFAENSKIIADISRIVYEY- +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Nostoc carneum NIES-2107 TaxID=1973483 RepID=A0A1Z4HZQ9_9NOSO +--SLKTAVQNLAAANSLTPGVLLVDLDTGSYV-DINSAASFPAASTIKIPILVAFFQDLD +AGKIRLDEMLTMQQSMIAGGSGNMQYKPAGTYSALEVATKMITISDNTATNMLIARLGGI +EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVNMRSRD +RLLDIMRQTER-DNLLPSGLGTGATIAHKTGDIGT-MLADAGLVDIPTGKRYIAAVMVQR +PNND-ARAEKLISGISRAAYQQf +>[subseq from] Beta-lactamase n=2 Tax=Sphingopyxis sp. MC1 TaxID=1174684 RepID=N9WE64_9SPHN +---LSDRISQLWRTFPGKTGIAVQRIDGEWSF-SERGGELFPQQSVSKLWVAMTVLDAVD +QGKLSLDRQVDIGPNDLTLHQPLAARVRSEGMSVRDLIETAITHSDNTANDSLLRTVGGP +EAVRRFIAKKGLGSIRFGPGERLLQSAYLANPMDGAAPAAIASALTRLARGALLSPESTQ +YLMGVMSRTHSGPKRLKAGLPSGWDFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGD +TSASIPARMALMQAVSGAVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia seriolae TaxID=37332 RepID=A0A0B8N725_9NOCA +------------------------------------------------------------ +-------------------------------MTVSELCDAAITRSDNTAGNALLKLLGGP +EALTAFTRTLGDQVTRLDRWEPDLNTDIPGDERDTTTPAALAADYRALVLGDALPAPERR +QLTDWLLANKTGDARIRAGLPGDWRTGDKTGSGDYGTANDAAITWPADGSPVVIVVLSSK +PDAAATADNPLVAAVAKEA---- +>[subseq from] class A beta-lactamase n=1 Tax=Alistipes sp. Z76 TaxID=2304565 RepID=UPI001370C63A +-rTLERRLAEYLDTLPVRAGVFVR-TDDGMEA-GYNADEEFPMLSTFKFPVALAVMAKME +RDGAEPSRPATVSARQLLPYSPMRERYGQRDTTLGQLLAYCVSQSDNNACDILIDYAGGI +DSVAHYVARTGVAPMRITATEQTMHTATERQRDNTSSPRAMVELLSLFREGRLLSQPYRD +TLMRYMTETSTGRDKLRAGISENAVSAHKTGSSDRTADNDVGIISLPDGRVCCIAVFVCD +SPMSDAENAAVVANVARMVCEEw +>[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. SYSU G00007 TaxID=2202251 RepID=UPI000D6E443F +---IQQQVEAIAAEGRGRIGVAAMDLDGGGQI-FINPDMAFPMASTAKIAVAATFLEQVE +KGNYRLDQQFPLMLPVRETISPEAPLRAGDLMTAQTLMELMITRSSNEATDGLLQVVGGV +ENVNRWLTRNGIAGQRLDHTMATLVRAKVIDTRTSSTPRAMIALLAAIDRGGVLSPESRA +VLLDTMTRTSTGKTRIRAGLPEGTLVAHKTGTLW-GVTDDVGIVRLPDGRHLAVAFFVTG +PEG-HAAHAKLIARMMRVIYDGy +>[subseq from] Serine hydrolase n=1 Tax=Nostocales cyanobacterium HT-58-2 TaxID=1940762 RepID=A0A1Y0RII7_9CYAN +----KTVVQNLAAANNLTPGVFLVDLDNGSYV-DINGSSSFSAASTIKIPILVAFFQDVD +AGKIRLDETLTMQKEMIVGGSGDMQYKPAGTFNVMEVATKMMTISDNTATNMLMTRLGGI +ESLNQRFRSWGLTTTAIRSPLPDLQGT------NTTSPKELGNLMAMVSKGNLVSMPSRD +RMLDIMRRTVR-NHLLPTGLGQGATIAHKTGDIGT-TLADAGVVDMPTGKRYIVSVMVQR +PNND-SRAEKLIGSISRAAYQQf +>[subseq from] class A beta-lactamase n=1 Tax=Scytonema tolypothrichoides TaxID=1233230 RepID=UPI0009FB2CDA +--TLQRKLEAVAKESDGRVGICAEEIKSGVIT-CVNGDQRFSLQSVMKLVVAAAVMDAID +RGQMRLEDVVTVRKNDLSLVQPIADLVAERGTTVADLISGAVIESDSAATDLLFARVGGA +EGIRTFLKTKRISGLSVDRDEKHLQTAYLKDKRDTATPRGMVTFLSALASGKLLSVKSTA +HLLKVMQATVTFPDRLKAGVPEGWTLGHKTGTSLTAVTNDVGILTAPDGGTISVAVFVAE +SRRSSKERAKVIAATAKTITSSy +>[subseq from] Beta-lactamase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A326GHX9_9SPHN +-sALEERIAQLADGSSGRIGVAAIDLTNGHTV-SVLGDQRFPMASTSKIAVAATFLEGVE +QGRWSLTSEFPLLLPRRSASSKVAPVYEGQHMKAIDLIEIMITRSSNPATDALLRVVGGP +KAVTNWVHRQGIRDWSIDRDIATLVRARHIDVRDSSTPTAMLELLSGLYQGKYLSAESRR +VLLGAMSRTRTGKRRIPALMPAGVKVSHKTGSLNN-TSSDVGFLETADGRTVAVAIYVTG +QG-TRLNREAKIAQIARALHDGy +>[subseq from] Penicillin-binding protein n=1 Tax=Scytonema tolypothrichoides VB-61278 TaxID=1233231 RepID=A0A0C2QXT7_9CYAN +--------QNLAAANNLTPGTFLVDLDNGSYV-DVNASSSFSAASTIKIPILIAFFQDVD +AGKISLDETLTMTKRMVVGGSGDMQYKPAGTFTIMEVATKMITVSDNTATNMLIDRLGGI +ETLNQRFRNWGLTTTTIRNPLPDLEGT------NTTSPKELGKLMGMVNKGNLVSVASRD +RILDIMRRTVR-NHLLPSGLGSGARIAHKTGDIGT-TLADAGLIDMPTGKRYVLAVMVQR +PSND-PRAEKLISSISRAAYQQf +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. YR768 TaxID=1884365 RepID=A0A1H9U402_9SPHN +--KLLAEFTRFAALSDGTVGIAVRDLQTGETQ-AFNGDTLFPMASAYKVAVAGRIFSLID +AGDLRLDDKLVLDPALASEGIAWMFSRPGASLSVDRLLELMLQKSDNNATDVLVARAGGP +TAITAFVTKLGVTGLRVDSDTAHLLYAFSIEPEDTSTPTAMLDLMTAYEEGRAMSAASTQ +RFFTIMAHCETGKARIKGMLPPGTAVAHKTGSLN-GVGNDVGIVRLPDGRRIAMVVFVMK +DSKGHVSRDRIIAEASRAAYDYf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Alistipes finegoldii TaxID=214856 RepID=A0A174CUZ0_9BACT +--QFESRLDEIVSEHKAFVGVAVR-TPGGETI--ARNDTLLPMMSVFKFPVALAVLDRMQ +REGIPLTQPISITPDLLLPYSPMRDSLPAGGLTLGQLLRYMVSESDNIACDILLREAGGP +EAVEAYVRSLGIGGIRIAASEEEMHHGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA +LLQRLLCGTTTGANKLKAGLPASTVIGHKTGSSDRTADNDVGYVVLPDGRRYCIAVFVTE +SEENDATNAAIAASASRAAYEYf +>[subseq from] Beta-lactamase class A n=2 Tax=Algoriella xinjiangensis TaxID=684065 RepID=A0A1I4Y847_9FLAO +-tDLRQKLTEIISKQDAEIGISLRMIENNDSL-TINGNLNAPMMSVFKFHIALAVLDLVD +KGKLSLNQKIFVRKTDLHAWSPMRDDYPEGNLTLDKILRYTVSDSDNNGCDILIDLVGGT +KAIQDYIDKIDVKDFTIKVNEQQMST-WENCYLNTTTPIAMTDLLVDFYKGKILKKKSTK +YLIQLMEQNSRGTTWMKGQLPKNTVVAHRTGISNQNAHNDVGIITLPNGKHFVLSIFQKN +IKQTQEISAQTMAELTKVIWDYy +>[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides finegoldii TaxID=338188 RepID=A0A1Q6HDZ1_9BACE +-sQLKTLLEQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQAVALADYMD +KKKLPLGTLLSIKKSDLKPYSPLRDQFPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DSVNRYIQSLGIRDCEITHTENDMHEDLDLCYNNWSTPLAAAKLLEIFRRKTLFDEAYKD +FIYQTMVECQTGQDRLVALLDKGVTVGHKTGTGDFNGCNDIGFVLLPNGHAYSIAVFVKD +SAESSLENSKIIADISRIVYKY- +>[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter sp. IPPAS B-1204 TaxID=2483793 RepID=A0A3M9YUW2_9SPHN +--NWQQRIAELADPAQGRIGVAAIDLATGEEV-MVLGDQLFPMASTSKIAVAATFLEMVE +QGRYSLTSEFPLMMPVASAYSSTKAPRPGQYMPAIDLIEIMITRSSNPATDALLAAVGGP +AKVNDWMRRHGIAEFSINRDIATLVRAVHIDTRDAATPRAMVRLLSGLYRGEFLSDQSRQ +VLLAAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGIIECPDGRVIAVAIYVTG +QG-TKLAREQRIAAIARALYDGf +>[subseq from] Serine hydrolase n=1 Tax=Nostoc minutum NIES-26 TaxID=1844469 RepID=A0A367RYJ8_9NOSO +--SLKDAVQNLATTNSLSPGVFLVDLDTGGYV-DVNSSTSFPAASTIKVPILVAFFQDVD +AGKVRLDEMLTMQQDTVAGGSGQLQKPLGTQYNALEVATKMITISDNTATNMLIARLGGM +DALNQRFRSWGLTTTMIRNALPDLQGT------NTTSPRELANLMAMVNQGNFVSMRSRD +LMLDIMRRTQR-DNLLPSGLGTGARIYHKTGDIGT-MLADVGLVDTPTGKRYIAAVMVQR +PNND-PRAEKLISSISRAAYQQf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. 3_1_23 TaxID=457390 RepID=D7K728_9BACE +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTI-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP +NAVNKYIHSLGIRECAIAGTETAMHQDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIANISRIVYEY- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. KVJ20 TaxID=457944 RepID=A0A1E2WEP5_9NOSO +--SLKNAVQNLADTNNLTPGVFLLDLDTGNYV-DVNGSTSFPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMQQDMVAGGSGNLQKSPGTQYAALEVATKMITISDNTATNMLITRLGGI +DALNQRFRSWGLTDTIIRNQLPDLQGT------NTTTPKELGNLMAIVSQGNLVSMPSRD +LMLDILRRTQR-DSLLPSGLGAGARVYHKTGDIGT-MLADAGLIGVPTGKRYVAAVMVQR +PNND-PRAEKLISSISRVAYQEf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sphingomonas sp. HMWF008 TaxID=2056845 RepID=A0A2R7JSZ3_9SPHN +--ALAASVASLVRGFDGRVGVAVRSIDQGWTV-DSNGDQRLPQQSVSKLWVAMTVLDLRD +AGRLRLDDPVTVRREDLTLHQPIAALVKGEETTVGELLQRALTMSDNTANDRLLRFVGGP +SAVRDFLQRKGLSNIRFGPGERLLQARYVSDPPDGAAPVAIANALARLKRGDLLTKASSD +YLIGTMESSRTGKQRMRGAVPPGWSFGHKTGTGQTAGYNDVGLLIAPDGKSYAIAVMIGD +TPKSIPERQALMQAVVASVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Tolypothrix sp. NIES-4075 TaxID=2005459 RepID=A0A218QGQ4_9CYAN +---LKSAVQNLALASNLTPGVFLVDLDSGAYV-DVNAGASFPAASTIKMPILVAFFQDVD +AGKIRLDETLTMQQDMVAGGSGNMQKPVGTQFTALELVTKMITISDNTATNMLIAKLGGI +EALNQRFRSWGLTTTVIRNKLPDLEGT------NTTSPKELGNLLALVNQGNLVSMRSRD +RLLDIMRHTEK-DTLLPSGLGVGATVAHKTGDIGT-MLADAGLVDMPTGKRYIAAVMIQR +PNND-PRAEKLISAISGITYQQf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina sp. RZ0 TaxID=2607730 RepID=A0A5B1B3G0_9FLAO +---LRKRIEKILEDKSTTVGIAIRGINPRDTI-SINGNKRLPMQSVFKYHLALAVLHQVD +QGKLSLDKVISMDKELLESWSPLRKRYPNGGVTLADILKTTVAWSDNVGCDILFKLVGGT +DVVQSYIHNIGIKDIAIVHTEIAMQSEWQNQYENWTTAKAANQILQLFFEDNLLSNQSYI +FLLDVLKSTKTGKKSIKGLLPKETIVAHKTGYSGTGALNNIGIIFLPDDSYFYLSVLVSD +SKESDETNQRIIAEIAKLTWDYf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides acidifaciens TaxID=85831 RepID=A0A4S2AV71_9BACE +---LEAQLKEAIKDKKAEIGIAVI-IDGKDTI-TVNNDNHYPLMSVFKFHQALALADYMA +KHKQSLDTLLKIEKSDLKPYSPLRDKYPQGEMSIADLLRYTLQQSDNNACDILFNYQGGT +DAVDKYIHSLGIQDCAIVGTEAAMHEDLDLCYQNWSTPLAAAELLEIFRREPLFAKEYKD +FIWQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRTYSIAVFVKD +SEESFADNSKIIADISRIVYEY- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. AP49 TaxID=1144307 RepID=J2L9V4_9SPHN +--HLLAEFDRFAALSDGTVGIAAMDLQTGEIQ-ARNGDTLFPMASAYKVAVAGKILSLVD +AGSLRLDDRLALDPALASEGIAWMFSRPGSTLPVSQLLDLMLTRSDNNATDVLVARAGGP +QAVNDWVAALGVHGLRVDSDTAHLLYDFMLDPRDTATPLAMTALLAAYEAGRALKPESTQ +LLFTIMGHCQTGKARLAGMLPPGTAIAHKTGSLN-GIGNDVGIINLPDGRRFAITVFVMK +DSRGHVSRDRIMAEAARAAYDYf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. HF-5300 TaxID=2594945 RepID=A0A553KVB4_9BACE +-sQLKTLLEQAIKGKKAEIGIAVI-IDGKDTV-TVNNDTHYPLMSVFKFHQAVALADYMD +KKKLPLGTLLSIKKSDLKPYSPLRDQFPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DSVNRYIQSLGIRDCEVTHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRRKTLFDEAYKD +FIEQTMVECQTGQDRLVALLDKGVTVGHKTGTGDFNGCNDIGFVLLPNGHAYSIAVFVKD +SAESSLENSKIIADISRIVYKY- +>[subseq from] class A beta-lactamase n=1 Tax=Mastigocladus laminosus TaxID=83541 RepID=UPI0009082A83 +---LEARVQSIGRAFNGDVGIAVRDVSTGWTT-AYDGDTFFPQQSVSKFWVQLTALDRVD +QGKLDLASSVTVGRDDLTLHQPIRAMVLKNGTTLSDLMHRAITQSDNTANDFVLWKAGGP +EAVRAFLQKNGLDGIRFGPGERLLQTRYIADPMDGATPRAVVEALARLKRGELLSPASTS +RILAIMSNTRTGAQRLKGGLAPGWSLAHKTGTGQQAGYNDIGLLTGPGGRSYAVAVLIRR +TSAPLPQRMAMMQNVTRAVID-- +>[subseq from] Uncharacterized protein n=1 Tax=Emcibacter congregatus TaxID=2043170 RepID=A0A2G4YVP2_9PROT +---LLQEIRRIAERNRGNVGVAVRHLETGKLL-SFNGDAQFLMASTYKIPIAVRILQLVD +QGKLSLDDLIEIRKDEYVSWSIIADRFNRGPISISNLMELMLVLSDNTATDVLLRIAGGG +KAVTAMLRDQNIKEMTVSRGTKDLIIYLSRNNDDKAEPNAMLQLLDNIWTGDILTNSSKK +ILQKIMERCETGKGRIKGKLPKNTIVMHKTGTLDHGVINNVGVIQLPNKGNIAIVVYTKD +AGKGIEFNEEIIADISQAVYNYf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A5M5B4X5_BACOV +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLETRLPIKKSDLKPYSPLRDKYPQGEMSIADLLKYTLQQSDNNACDILFDYQGGP +DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPNVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIANISRIVYEY- +>[subseq from] Beta-lactamase BRO-2 n=2 Tax=Moraxella TaxID=475 RepID=A0A066UD53_9GAMM +---LKEILPIWENKFNAKIGMTIIA-DSGEIS-SHRGDEYFPVNSTIKAFIASHILLLVD +KGKLDLNEKIIIKESDLIEYSPVCKKYFNENISISELCEATITLSDNGSANILLDRAGGL +TAFNQFLKEIGAD-MVLANNEPLLNRSHYGETSDTAKPIPYTRSLKALITDNILSNQSKE +QLITWLINDKVADNLLRKYLPKNWRIGDKTGTGSE-SKNIIAVIWNENNKSYFVSLFITQ +PHDGKNQKDEIMAQIGKEIY--- +>[subseq from] Beta-lactamase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8SRN4_9BACT +-nALQNELTTLVEVAKGRVGVGAVLVETGQTV-YLDRKGQYPMQSVYKLPIAMAVLKMID +DGKVKIDQDVSITPDDFVRHSPIRNVNPQGTMNVYGIMRYSISESDGTASDVLLDLAGGP +DAVMNYLKSIGITEVIVADSEKSISKDWETQYRNWATPEASIELLEHLYGRRALSEQSTN +LVLDFMTNSDTGGRRIKRGLPEGASIAHKTGTGGTGATNDMGIVTLPDGNHLLIVIYIAD +SKETGFARQQLFGDVARAIIEKw +>[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. SG707 TaxID=2586996 RepID=UPI001445EFB8 +---FEARLAQLAGASQGRIGVAAVDLSSGRGV-SVMGDQPFPLASTGKIAVVATFLEGVD +QGRYKLSDRFPLMMPVPSASTAVAPVRPGAMLSAEQLIELAITRSDNHATDALLAAMGGP +QVVTRWLRRNGINGIRLDRDIATMVRARKIDLRDSTTPQAMAVLLAGLYQGQWLSAQSRE +VLLGAMARCRTGIHRMRAALPGDAMVGHKTGTLSN-TSSDVGLIRSSDGRTIAVAIYVTG +QG-GKPGRDQRIASITRAIYDGy +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. SCN 63-17 TaxID=1660120 RepID=A0A1E4MZ94_9SPHN +---FEARLAQLAGASQGRIGVAAVDLSSGRGV-SVMGDQPFPLASTGKIAVVATFLEGVD +QGRYKLSDRFPLMMPVPSASTAVAPVRPGAMLSAEQLIELAITRSDNHATDALLAAMGGP +QVVTRWLRRNGINGIRLDRDIATMVRARKIDLRDSTTPQAMAVLLAGLYQGQWLSAQSRE +VLLGAMARCRTGIHRMRAALPGDAMVGHKTGTLSN-TSSDVGLIRSSDGRTIAVAIYVTG +QG-GKPGRDQRIASITRAIYDGy +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9B5Y5_9BACT +-tALQQKISVIAADARGKVSVACSLPGSDLNC-DLNPHTRPPMQSVFKLPLVMTSLHLIE +ERKFSLDQPVRFLPSDRILHSPLQDKYPEANIPLRELLRLAVSLSDNSAADLVLRVIGGP +EVVQRYMNSIGVDGFQLKDGERGLHGDVAAQYRNWFEPASAVKLLRRISDDSPLSAEHTA +LLLAWMKDTPTGAHRIKGELPEGTNVMHKSGTSGSGATNDIGLIALPNGRRLAIAIFVTD +AAADDATRDAVIARIAKAAYD-- +>[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=Bacteroides TaxID=816 RepID=A0A5M5EKY6_BACOV +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLETRLPIKKSDLKPYSPLRDKYPQGEMSIADLLKYTLQQSDNNACDILFDYQGGP +DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPNVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKN +SEENNQANSKIIANISRIVYEY- +>[subseq from] Beta-lactamase BRO-1 n=12 Tax=Bacteria TaxID=2 RepID=BLA1_MORCA +---LKEILPIWENKFNAKIGMTIIA-DNGELS-SHRGNEYFPVNSTIKAFIASHILLLVD +KEKLDLNEKIIIKESDLIEYSPVCKKYFDENISISELCEATITLSDNGSANILLDKIGGL +TAFNQFLKEIGAD-MVLANNEPLLNRSHYGETSDTAKPIPYTKSLKALIVGNILSNQSKE +QLITWLINDKVADNLLRKYLPKNWRIGDKTGTGSE-SKNIIAVIWNENNKPYFISLFITQ +PHDGKNQKDEIMAQIGKEIY--- +>[subseq from] Uncharacterized protein n=1 Tax=Alistipes sp. CAG:29 TaxID=1262694 RepID=R6Z1Q2_9BACT +--QFESRLDEIVSEHKAFVGVAVR-TPGGETI--ARNDTLLPMMSVFKFPVALAVLDRMQ +REGIPLTQPISITPDLLLPYSPMRDSLPAGGLTLGQLLRYMVSESDNIACDILLREAGGP +EAVEAYVRSLGIGGIRIAASEEEMHHGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA +LLQRLLCGTTTGANKLKAGLPAEIVIGHKTGSSDRTADNDAGYVLLPDGRRYCIAVFVTE +SEENDAANAAIAAAVSRAAYEYf +>[subseq from] Beta-lactamase class A n=1 Tax=Prauserella rugosa TaxID=43354 RepID=A0A660CCF4_9PSEU +------------------------------------------------------------ +-----------WTDEDLVLNSPVTENTVRNGLTVAQLAEATVTVSDNTAANVLMREFGGP +AAVTAFARSLGDRVTRIDRWEPELSTGTPGDERDTTSPRSIAGTYASLVVGRALSRPDRE +RLTTWMLANQTAGPVFGAGVPAGWALADKTGAGWYGARNDVGITWTPDGAPLVIAAFTHG +RAYEDDSLDEPLAAIAESAC--- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A5M5C2Z6_BACOV +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDTHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNVCDILFNYQGGP +GAVNRYIHSLGVRECAIIGTETAMHEDLNLCYQNWTTPLAAAELLEIFHKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRIYSIAVFVKD +SEENSQANSKIIADISRIVYEY- +>[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. CCH11-B1 TaxID=1768781 RepID=UPI00082BCD9D +--KLLGEFARFATLSDGTVGIAVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRIFALID +AGQLKLEDQLALDPALASEGIAWMFSQPGAHLSVDRLLQLMMQKSDNNATDVLVARAGGP +QAITQFVTGLGVRGLRVDSDTAHLLYAFAAEPEDTSTPTAMLDLVTAFEAGRALSPASTQ +RLFTIMAGCETGKARIVGMLPPGTAVAHKTGSLN-GVGNDVGVVRLPDGRRFAVVMFVMK +DSKGHVSRDRVIAEAARAAYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Phenylobacterium sp. CCH12-B4 TaxID=1768784 RepID=UPI00083A2012 +-------ISAIAGAAPASLGVGLSNLESGQTYiRLGQHRRFPMQSVFKLPLAAAVLAEAD +AGRLMLTEPFVLTEEQLSPVSPIAAGWPARRYTAQALFEAMVVDSDNTAADVLMKRIGGP +GAVTAWLTARRVPEVRVDRYERELQPRYMSDPRDTTTPRGMLELLQMLDRQELVSPASTK +RLLELMGRTRRGVGRIRAGLPRDAFLAHRPGTSGSTAHNDVGIFTLADRRSYALAVFLSG +STLDEAGRDRIIAEVARAAL--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A649VZ78_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDGTEPTLNTAIPGDPRDTTTPRAMAQTLRNLTLGK-------- +------------------------------------------------------------ +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Alistipes onderdonkii TaxID=328813 RepID=A0A656Q3R1_9BACT +--QFESRLDEIVSEHKAFVGVAVR-TPGGETI--ARNDTLLPMMSVFKFPVALAVLDRMQ +REGIPLTQPISITPDLLLPYSPMRDSLPAGGLTLGQLLRYMVSESDNIACDILLREAGGP +EAVEAYVRSLGIGGIRIAASEEEMHHGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA +LLQRLLCGTTTGANKLKAGLPASTVIGHKTGSSDRTADNDVGYVVLPDGRRYCIAVFVTE +SEENDATNAAIAASASRAAYEYf +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000D009432 +hdALQATLERFAQAAPGTLGVVVLDLERPARW-QVNGTLPFPMMSVFKAPLGATVLDLSE +QGRLPLGHRITITRDQLRGHSPIRETFQSQQFTVDTLLRAAVSDSDNTAADALLRAVGGP +VVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR +RLLGLLRDQTQ-PRRLRAGLPPGVTFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA +SRASRAERERLFADLARAVAS-- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013A53C11 +------------------------------------------------------------ +-------------------------------MTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHGTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. T09 TaxID=1932621 RepID=A0A252E654_9NOSO +--SLKTAVQNLAAANNLTPGVLLVDLDTGAYV-DVNSATSFPAASTIKIPILVAFFQDLD +AGKIRLDEMLTMQQQMIAGGSGNMQYKPAGTYTALEVATKMITISDNTATNMLIARLGGI +EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVNMRSRD +RLLDIMRQTQK-DTLLPSGLGAGASIAHKTGDIGT-MLADAGLVDIPTGKRYIAAVMVQR +PNND-LRAEKLISAISRAAYQQf +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroides finegoldii CL09T03C10 TaxID=997888 RepID=K5CAA1_9BACE +-sQLKTLLEQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQAVALADYMD +KKKLPLGTLLSIKKSDLKPYSPLRDQFPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DSVNRYIQSLGIRDCEITHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRRKTLFDEAYKD +FIYQTMVECQTGQDRLVALLDKGVTVGHKTGTGDFNGCNDIGFVLLPNGHAYSIAVFVKD +SAESSLENSKIIADISRIVYKY- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingopyxis flava TaxID=1507287 RepID=A0A1T5A0P8_9SPHN +---LEQRIFELWRSFPGKTGIAVQRIDGEWTL-QQRGDELFPQQSVSKLWVALTVLDAVD +RGALTLDRKVSITPADLTLHQPIAARVRAEGMSVRELIETAITHSDNTANDSLLRTVGGP +DAVRRFIAAKDLGAIRFGPGERLLQSNYLANPVDGASPSAIARALTRLARGTLLSPQSTD +YILGVMSRTRSGPNRLKAGLPSGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGS +TTASIPQRMVLMQAVSGAVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Dysgonomonas mossii DSM 22836 TaxID=742767 RepID=F8WVR0_9BACT +---LRNKIQKIIEGKDATVGVALI-VDGKDTL-TINNNFRYPTQSVYKFHLALAVLDYLN +KNNLTLDHQVYVKKSDLLPHSPLRGDYPHGELSVADLIKYTVSNSDNNACDILFRLVGGT +AEVDKYIRGLGLSEFAIAATEEEMHGPWDVQYTNWSTPYTTAQVLEIFRTQNILPQPSHE +FLWNALAGTTTGENKIKELLPEGTFVAHKTGSSFRNAENDIAIIQLPDGRYYSLVVFVAD +SMESNDVNCGIIAQISKAVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A651HTW1_9BACT +-eRLEAELARFEPLSGGTLGIHAVHLETGRSV-GLNADDAFPMASTYKVPMAYQLLRRVD +AGEVRLDSLVHLQQHHFSPGSGTLSDFIQPGLSVRNLLELTLLISDNTATDLILEIAGGG +EAVTSAMQDAGFGGVRVDRSTLQLIAAFEMDVRDTATPRAMASLLEAVWRDEGLSPESAG +LLRDIMERCRTGEGRIRGLLPDFVTTANKTGTIG-GTLNDVGAIELPDGGTVLVAAFIKG +SDQPNPRREAALAGAVRAIYDYf +>[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A521PVR8_9CAUL +--------------RPANLGVGLINLESGETF-VFNGDRRFPMQSVFKLPLAAAVLAEID +AGRAVFTEPFVLLETQLSPFSPIAAAWPGRRYSLRELFEAMVIDSDNTAADVLMKRIGGP +GAVTAWLAGRHVAEVRVDRYERELQPAYMADPRDTATPLGMLDFLQMLDRQELITPASTR +LLLQLMGRTSRGNARIKAGLPGNAFLAHRPGTSGSTAHNDVGIFTLADRRSYALAVFLSG +ATLDDAGRDRIIAEVARAAVR-- +>[subseq from] Beta-lactamase, putative n=2 Tax=Coleofasciculus chthonoplastes TaxID=64178 RepID=B4W2U5_9CYAN +---LKAQVQTLVAKNKLQPGVFVVDLDTGAYL-DWQSHSIFPAASTIKVAILVAFFQEVD +AGKIRLDEPLTMEPEMIAKGSGDMQQKPGTQYSALEVATKMITISDNTATNMIIHRLGGI +QAVNQRFISWGLTATAINNPLPDLEGT------NTTNARDMANLLYKVNQGELLSLRSRD +RLLDIMQRTVN-NSLIPQGLDSGATVAHKTGDIGS-VLGDVGIVDMPTGKRYLIVTLVKR +PHND-ASASELIRNLSRTVYDYf +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X8Z8_9BACT +--SLQKDLQRVVTESDGKVGICSWSLAASEAV-CINGLERFPLQSVMKLIVSAAVMDAID +QKRMKLEDLITVKPEHASPPQEFADLVRKKGVTVEELMRRSIVDSDSTSIDILIEKLGGM +RTVQSFLKAKNITDIRIDRNERDLQSTYLKDPRDTATPLGMVKFLKALAEGKLLSRTSTE +KLLSIMEMTVTGPDRLKAGLPPGWKIGHKTGTSFAAATNDVGILTAPNAARIAIAVFVTD +SRHSPDERALVIAKAAKAVTGSf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingorhabdus sp. EL138 TaxID=2073156 RepID=UPI000D698353 +--ALERQIAELWRTFPGKTGIAIKSIDGGWSI-GHRADQNFPQQSVSKLWVAMTLLDKVD +QGRISLSDSIRIGPDDLTLYQPLAAEVKREGKSVYTLLERALAYSDNTANDALLRHAGGP +EAVNDFIRRSRLGKIKFGPGERLMQSDYLADPIDGASPDAIVNALDQLARGKLLSANSTQ +LLQSILKRTRSGPKRLKAGVPSDWEFLHKTGTGQSTGYNDVGIMTAPDGSRYAVAVMLGD +TTAPIPERMRMMQAVTRAVASY- +>[subseq from] serine hydrolase n=1 Tax=Nostoc sp. T09 TaxID=1932621 RepID=UPI000A36AA59 +--SLKTAVQNLAAANNLTPGVLLVDLDTGAYV-DVNSATSFPAASTIKIPILVAFFQDLD +AGKIRLDEMLTMQQQMIAGGSGNMQYKPAGTYTALEVATKMITISDNTATNMLIARLGGI +EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVNMRSRD +RLLDIMRQTQK-DTLLPSGLGAGASIAHKTGDIGT-MLADAGLVDIPTGKRYIAAVMVQR +PNND-LRAEKLISAISRAAYQQf +>[subseq from] Serine hydrolase n=1 Tax=Legionella sp. TaxID=459 RepID=A0A2H9SXB9_9GAMM +-kDLLKKIRAIEQQNHTTLGITAIHIEHNKKI-AHNSAQRFFMASTIKVPIAIALLHRVD +QKKEALNRVIKMDTKNSVPGSGNLHYVFEKKMSLQQILKHMLVHSDNSASDTVLKAVNGP +QYVTQYMYALGFKNMVISRSILEMLLKFQKDYRDTTTPDEMARLLVKLQKQQILSASSTQ +LIMSIMEQCRTGRSRIKGLLPSYVKVAHKTGTWSYRFASDVGVITLPNNGHVAIAVYVKS +QSASDYPRSRSIALASRAIYDYf +>[subseq from] class A beta-lactamase, subclass A2 n=3 Tax=Bacteroidaceae TaxID=815 RepID=UPI00125F0659 +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTI-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP +DAVNKYIHSQGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPNVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIADISRIVYEY- +>[subseq from] class A beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=UPI000AC7F63E +-----------------------LDLNSVKILeSFRPEERFPLLSPLKVLLCGAVLARID +AGQEQRGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITSSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWM------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas indica TaxID=941907 RepID=A0A1X7H068_9SPHN +---LEARVQSIGRAFNGDVGIAVRDVATGWTT-AYDGDTFFPQQSVSKFWVQLTALDRAD +QGKLNLANSVTVGRDDLTLHQPIRAMVLKNGTTMSDLMHRAITQSDNTANDFVLWKAGGP +DAVRAFLHKNGLDGIRFGPGERLLQTRYIADPMDGATPRAVVEALARLKRGELLSPASTS +RILGIMSNTRTGAQRLKGGLAPGWNLAHKTGTGQQAGYNDIGLLTGPDGRSYAVAVLIRR +TSAPLPQRMAMMQDVTRAVID-- +>[subseq from] BRO-2 n=4 Tax=Moraxella TaxID=475 RepID=Q49095_MORCA +---LKEILPIWENKFNAKIGMTIIA-DNGELS-SHRGNEYFPVNSTIKAFIASHILLLVD +KEKLDLNEKIIIKESDLIEYSPVCKKYFDENISISELCEATITLSDNGSANILLDKIGGL +TAFNQFLKEIGAD-MVLANNEPLLNRSHYGETSDTAKPIPYTKSLKALIVGNILSNQSKE +QLITWLINDKVADNLLRKYLPKNWRIGDKTGTGSE-SKNIIAVIWNENNKPYFISLFITQ +PHDGKNQKDEIMAQIGKEIY--- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. SCN 62-14 TaxID=1660099 RepID=A0A1E4AYL7_9SPHN +--SLEARIADLANPARGRIGVAAVDLTTGEEV-MVLGDQLFPMASTSKVAVAATYLEMVD +RGQASLTSEYALLLPVASPSSPKAPVRPGNYMPAIDLIEIMITRSSNPATDSLLAAVGGP +ATVTSWMRRHGFNDFSINRDIATLVRASRIDPRDAATPRTMVRFLQGLYRGDFLSPQSRQ +VLLGAMSRTVTGKRRIPAQMPYDARVSHKTGSLNN-TSSDIGLIETPDGRVIAVAIYVTG +QG-TRAAREDKIAEIARALYDGf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. AM56-10ce TaxID=2302926 RepID=A0A373GA16_9BACE +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLGTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIANISRIVYEY- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingobium sp. Z007 TaxID=627495 RepID=UPI000B49BAAD +--KLLGEFARFAALSDGSVGIGVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRILALVD +AGEARLDDQLALDPALASEGIAWMFSRPGATLSIDRLLELMLQKSDNNATDVLVARAGGP +QAITGFVNKLGVTGLRVDSDTVHLLYAFANEIQDTSTPAAMLDLIAAYESGRALSAASTQ +RLFTIMANCETGKKRIVAMLPPGTAVAHKTGSLN-GIGNDVGVVRLPDGRRFAIAVFVMK +DGKGHVARDRIIAEAARAAYDYf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides acidifaciens TaxID=85831 RepID=A0A3L7Z1Y8_9BACE +---LEAQLKEAIKDKKAEIGIAVI-IDGKDTI-TVNNDNHYPLMSVFKFHQALALADYMA +KHKQSLDTLLKIEKSDLKPYSPLRDKYPQGEMSIADLLRYTLQQSDNNACDILFNYQGGT +DAVDKYIHSLGIQDCAIVGTEAAMHEDLDLCYQNWSTPLAAAELLEIFRREPLFAKEYKD +FIWQTMVECQTGQDRLVALLDKKVTVGHKTGTGDHNGCNDIGFVLLPDGRTYSIAVFVKD +SEESFADNSKIIADISRIIYEY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavimarina sp. Hel_I_48 TaxID=1392488 RepID=UPI0005615695 +--DLKTSIENILKGKKAQVGVAIASNKSKDAI-NINNDFQYPLQSVFKFPIALTILSEVD +KGKFSIDQPIEISKNELAAWSPIKDKFPDGTLTLGEILAYTVAQSDNIGCDILLKLIGGT +ATVETFLKDNIIEDIVIKVNEQQMHEDWAAQYKNWGKPTALNELLIKAYRGQMLSHKSHE +LIWKIMRETTTGTKRLKGNLPQHVAVAHKTGTSGTRATNDIGVIELPDGEVIFISVLVVN +FQEQPETNEQLIAKISKAAFDYy +>[subseq from] Beta-lactamase n=1 Tax=Scytonema sp. HK-05 TaxID=1137095 RepID=A0A1Z4IMZ9_9CYAN +---LKTVIQNLAAANNLTPGVFLVDLDNGGYV-DVNGSSSFSAASTIKVPILVAFFQDVD +AGNIRLDETLTMQKEMVVGGSGDMQKPVGTQFTAMEVATKMMTVSDNTATNMLIARLGGM +QVLNQRFQSWGLTTTAIRSPLPDLQGT------NTTSPKELGNLMAMVSKGNLVSMSSRD +RMLDIMRRTVR-NHLLPTGLGPGATIAHKTGDIGT-TLADAGVVDMPTSKRYIVAVMVQR +PNND-ARAEKLISSISRAAYQQf +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. RF31YmG TaxID=1932668 RepID=A0A252D5Z8_9NOSO +--SLKTAVQNLAAANNLTPGVLLVDLDTGAYV-DVNSAASFPAASTIKVPILVAFFQDLD +AGKIRLDEMLTMQQQMIAGGSGNMQYKPAGTYTALEVATKMITISDNTATNMLIARLGGI +EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLLAMVNQGNLVNMRSRD +RLLDIMRHTER-DTLLPSGLGAGASIAHKTGDIGT-MLADAGLVDISTGKRYIAAVMVQR +PNND-PRAEKLISAISRAAYQQf +>[subseq from] class A beta-lactamase n=1 Tax=Mastigocladopsis repens TaxID=221287 RepID=UPI0002D9F5C8 +--SLKTAVQNLAAGTNLTPGVFLVDLDNGSYV-DVNGSSSFSSASTIKIPILVALFQDVD +AGKIRLDETLTMQKEMVVGGSGDMQKSAGTQFTVMEVATKMMTISDNTAANMLIGRLGGI +EVLNQRFRSWGLTTTAIRNPLPDLQGT------NTTSPKELGNLMAMLSKGNLVSVSSRD +RILDIMRRTVR-NHLLPTGLGQGATIAHKTGDIGT-TLADAGLVEMSTGKRYIIAVMVQR +PNND-ASAEKLIGSISRAAYQQf +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0012905CE1 +------------------------------------------------------------ +--QEQLGRRIHYSQNDLVEYSPVTEKHLTNGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGE-------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Swaminathania salitolerans TaxID=182838 RepID=A0A511BUH1_9PROT +--DLARLARNYERRSGGRIGIAIRGLSPGRMT-SWRGHERFLMCSTFKVSLVACILARCE +QGADDLTLRLPFTDEDIGTWAPVIRENRETGLSLAALCAGAITVSDNVCANLLLRHLCGP +RKLTQFWREEGDRVSRLDACEPALNHPAADPLANTTSPCAMTGTLDHLLYGSALNTDSKR +LLRGWMTHCRTGTSRLRSGFPPGWTCGDKTGSNGKDIAADIAFARPVDNHRVVISTYTAG +GAASPALLDATFREIGALAT--- +>[subseq from] Uncharacterized protein n=1 Tax=Alistipes sp. 58_9_plus TaxID=1896970 RepID=A0A1Q6FEK9_9BACT +-------------DIPARVGIYAED-SDGRTL-TYRADEMFPMLSTFKIPVAISVLKRTE +VTHTPLSHRIAIAAGQMRPYSPMLKRHPQGWATIDSLLSYAVSMSDNNACDILIDYAGGI +KAVAKTIEQAGIYPMTISATEEDMHRDIDNQRINVCSPRAAAYMLGRLANGELLTSASTE +ALIRHMTRTETGIDKLHAGLPQHIVMAHKTGSSDRTADNDIGIVFLPDGRSYIITVFIAD +SGLDDKANAALTAEISRIVYEAf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroidaceae bacterium TaxID=2212467 RepID=UPI0011DC9A2B +-tQLETQLKEAIKGKKTEIGIAVI-IDGKDTI-TVNNDIHYPLMSVFKFHQALALADYMG +KQKRSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP +DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRSYSIAVFVKD +SEENNRANSKIIADISRIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium deserti TaxID=1914756 RepID=A0A328ASL9_9CAUL +--ALEAEVGRIADRCPGVLGVGLMNLENLETW-LLNGERPFPMQSVAKLPLGAAVLAEME +AGHLRLDEVVQVQETDLSPFSPVADAWPQRTWTVRELLAEAVGQSDNTAADLLMRRVGGP +GAITAWLVSERIEEVRLDRYARELQPRYMADPQDTATPRGMLNFLQKLDSGQLVSPASAQ +LLLTLLKQNTAGATRLRAGLPPNASLFHKSGTSRNPATNDVGVFTLPNNRSYAIAVFLSG +TSLDGVALDQIIAEIARAAVR-- +>[subseq from] serine hydrolase n=1 Tax=Nostoc sp. RF31YmG TaxID=1932668 RepID=UPI000A3AB757 +--SLKTAVQNLAAANNLTPGVLLVDLDTGAYV-DVNSAASFPAASTIKVPILVAFFQDLD +AGKIRLDEMLTMQQQMIAGGSGNMQYKPAGTYTALEVATKMITISDNTATNMLIARLGGI +EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLLAMVNQGNLVNMRSRD +RLLDIMRHTER-DTLLPSGLGAGASIAHKTGDIGT-MLADAGLVDISTGKRYIAAVMVQR +PNND-PRAEKLISAISRAAYQQf +>[subseq from] Beta-lactamase n=5 Tax=root TaxID=1 RepID=F3QIV7_9BURK +--DLTSDIQEVIKGKKAQVGVAVLY--KDDAF-TANNDDQYPLMSVFKFHIALAVLKKME +KEGIPLTAVVTLGPSDIDTWSPMYKKYKSKKLSYGDLINYMVSQSDNNACNWLINFVGGI +QNVNDFIKNLGIDRIQLIETEKSMEQDIRKSYNNWSTPLSVTQLLRKVYTEKVLSDEHFA +FLEKAMLASASGKDKFRAGLPKEVEVGHKTGMSYRTCDADVGVIYMPGGEKCYLAVLVKD +SKETDAANAKIMADIAKKVYSHy +>[subseq from] class A beta-lactamase n=1 Tax=Spirosoma sp. HMF4905 TaxID=2682092 RepID=UPI0012FA55F1 +--RLEQELFRLSNLSAGKVGICAVHLESGKTI-TQNGKDHFPMASSYKVAIATQLLSRVD +SGSITLAQLVPILKTDFHPGSGMLSERFNWPLSVRSLLELMLLISDNSATDLCLRLAGGP +AAVNACMKRLGVEGLQVNRPTAWLIAAFENDIRDTSTPEAMTLLLTKLYTQPVLKPDSKT +LLLDIMKRCETGLARLKGALPPDTEVLHKTGTIGL-TASDVGIITLPGDGHVAISVFVKS +SKKEGPVRERTIAEVTRTIYDYf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides finegoldii CAG:203 TaxID=1263045 RepID=R6RUE9_9BACE +-sQLKTLLEQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIQYPLMSVFKFHQAVALVDYMD +KKRLPLGTLLPIKKSDLKPYSPLRDQFPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DSVNRYIQSLGIRDCEITHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRRKTLFDEAYKD +FIYQTMVECQTGQDRLVALLGKGVTVGHKTGTGDFNGCNDIGFVLLPNGHAYSIAVFVKD +SAESSLENSKIIADISRIVYKY- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI001370E3CA +htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNQVD +RGNLALDQKVLVKKSDLLEWSPIREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGV +KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. GV013 TaxID=2135688 RepID=A0A4R7DFZ5_9SPHN +---IEQQVAAIIAQGRGRIGVAAMDLDGGGQI-MINGDMPFPMASTAKIAVAATFLSGVE +QGRFRLDQSFPMMVRIAQPRGAIAPVRAGTVMSAQGLMELSITRSNNEATDGLIAAVGGI +ESVNAWLARTGIAGQHLDHTMATLVRARVIDTRTSSTPRAMIALLAAIDRGGALSPQSRA +VLLDTMTRTSTGRNRIRAGLPEGTLFAHKTGTLA-GVTDDVGIIRLPDGRHLAIAIFVTG +PE-NHTSQAGLIAQIAQVVYNGy +>[subseq from] UPI001446751E UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI001446751E +------------------------------------------------------------ +-DARALAELVRYSRADLLPGSPVTGEHLGRGLSLAALCEAAVRHGDRTAGNLLLRRLGGP +GALTRFARSVGDRVTRLDRWEPELNSAEPDRRTDTTTPYAIARTYAHLTVGDALGTADSC +LLTGWMRQHTAGPARFRAGLPAGWLLADTTGGGPYGTGHDVGIVWTPEGTPLLLACLTRG +AEPGEEPDDALLAETAALLA--- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides acidifaciens TaxID=85831 RepID=A0A4Y9GVL0_9BACE +---LEAQLKEAIKDKKAEIGIAVI-IDGKDTI-TVNNDNHYPLMSVFKFHQALALADYMA +KHKQSLDTLLKIEKSDLKPYSPLRDKYPQGEMSIADLLRYTLQQSDNNACDILFNYQGGT +DAVDKYIHSLGIQDCAIVGTEAAMHEDLDLCYQNWSTPLAAAELLEIFRREPLFAKEYKD +FIWQTMVECQTGQDRMVALLDKKVTVGHKTGTGDHNGCNDIGFVLLPDGRTYSIAVFVKD +SEESFADNSKIIADISRIVYEY- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A1G8I3R0_BACOV +-sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KKKQSLDTRLPIKKPDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +GAVNRYIHSLGVRECAIIGTETAMHKDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD +FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRIYSIAVFVKD +SEENSQANSKIIADISRIVYEY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dysgonomonas sp. HGC4 TaxID=1658009 RepID=UPI0006826B54 +-nELRKNIQSIIENKNATVGVAII-FNGKDTL-TVNNQYRYPTMSVYKFHQALAVLDNLN +RRNLPLDQQIYVSKAALQPHSPLREARPEGNMPIKELLQYSVSQSDNNACDILFDFLGGP +NYVEKYIKSLGIMQIAITATEQEMHDDPNKQYANWTTPYAAVELLEKFKQQDWFPSQSKS +LLWDALVETSTGKDKIKGLLPSGTVVGHKTGNSFRNADNDLGFIELPNGKQLSIAVFIVN +SMEDDKTNAAIIAQISKAAYDYy +>[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=2 Tax=Sphingobacterium lactis TaxID=797291 RepID=A0A1H5Z0K3_9SPHI +---LTAKIEQIIKAYDAKVGVAVHNQEFTEHH-FVNKDHKYPMQSVFKFHLGIAVLNQVD +SGKLRLDQDVVITKADVSNYSPIREKFPNGTMPLSQVLHHTIAQSDNVGCNVLFRMLGGP +DQVQAYFEKQGYTGIAIRNDESEIQGDWEVQFKNWIDIETSNKILYDYYTNDQLSESSYQ +FLWDTMRGTSTGRDRIKGLLPAGTVVAHKTGYSGQNAVNDIGVVTLPNDKVFYITVLVTD +AKEPEPNCAKIIAEVAKAAYDHy +>[subseq from] Beta-lactamase n=2 Tax=Akkermansia TaxID=239934 RepID=A0A5B5WI01_9BACT +------AIREIVRPLKAHVGVSAVMLDTGESV-SVGDEAFYPMQSVYKFPLALSVLKRVD +QGVLDLDQKVKVTRDQLPEWSPLRDRFPQGGFPLKELLRFSVQESDNNACDILFSLIGGP +ANVQKDLKEWGVENMNVKYTEADTHRNHEWQYSNSARPTAMTSLFRMFDEGKILKKDTQL +FLWDMMASCATGAERLKGLLPKEYVVAHKTGTGGVSAINDAGIIVLPGGRRMAVTVFVMN +SKDSPAVCEGTIASVARWLCTEw +>[subseq from] Uncharacterized protein n=1 Tax=Leptolyngbya sp. 'hensonii' TaxID=1922337 RepID=A0A1Q8ZIY4_9CYAN +--ALKTEVQALTAQNGLTAGVFFVDLDTGAYI-DLNGDSTFSAASMIKVPILVAFLQDVD +AGKIRLDEMLTMRPDLIGSGSGVIQYRTGTQFTALEIATKMIVISDNTATNMLIDRLGGI +AALNQRFQSWGLTGTLVYNLLPDLEGT------NVTRPKELATLMFRVSQGDLLSIRSRD +RMLDIMRRTET-DTLLPRGLDDNATISHKTGDIGS-MVGDVGVIDAPNGKRYVAVAMVKR +PHND-SRAQEMIRRISRAAYQAy +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium subterraneum TaxID=48936 RepID=A0A0B8ZKX3_9SPHN +-qAIQQQVAAIAAEGRGRIGVAAMDLDGGGQI-FVNADMPFPMASTAKIAVAATFLDLVE +KGNARLDQQFPMMMPVRETGARSAEAPLRSGMTAQSLMELSITRSHNEATDGLIQAVGGY +DKVNRWLTSKGITGQRLDHTMATLVRARVIDVRTSSTPRAMLALLAAIDRGNALSPESRA +VLLDTMTRTSTGKNRIRAGLPAGTLVAHKTGTLF-GVTDDVGIVRLPDGRHLAVVFFVTG +PEG-HTAHAGLIARMMRTIYDGy +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium GWB2_63_22 TaxID=1797929 RepID=A0A1F9SHD1_9BACT +-qEMVADLEKVSRAYRGRVGVYIKDLETGRTW-EYNADRLFPSASLIKVPIMAAVFEKMR +LGAFTLDTQIKLTRRERVGGSGSLKWVRDGTLSVMEIIYKMITESDNTATRMLIDYV-GM +DYLSVAFRELDLEHTNITQEGMSLKSG-RVARENYTTAREMASLLERIYAGELVNRESSE +FMLDVMKHTKS-RSRLRRGLPLGWEIGHKTGLLRK-ACHDVGIVFSPRGD-YVIAVLTSE +VP-SYSSAKIFISKVAKLTYHYy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1W5MZR2_9BACT +--DLSSDIQEVIKGKKAQVGVAVLY--KDDAV-TMNNDGQYPLMSVFKFHIALAVLKKMQ +QEGILLSAVVTLGPSDIDTWSPMYKKYKSEELSYGDLINYMVSQSDNNACNWLINFVGGI +QNVNAFIKDLGIDQIQLIETEKSMEQDIRKSYNNWSTPLSVVQLLRKVYTEKVLSDEQFA +FLEKAMLASVSGKDKFRAGLPKEIEVGHKTGMSYRTCDADVGVIYMPGGEKCYLAVLVKD +SKESDAANAKIMADIAKKLYEHy +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A0M3AZK7_9SPHN +------------------------------------------------------------ +---------------------------LGRPLPVRTLLDMSLTLSDNEATDALVARAGGP +QAVNDWVRAIGVRNLRVDSNTRDLLAGFATDPRDTATPRAMDDLLVAIRTGKALKPQSTA +MLLSIMERCRTGKDRLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRLFAITVFVMK +DYKGHQMRDRIMAEAARAAYDYf +>[subseq from] Class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A4P8WG27_KLEPN +------------------------------------------------------------ +--------------------------------QCRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. 519 TaxID=2302937 RepID=UPI0013D7B692 +hdSLRNQILSIIKGKNATVGVAVN-FDGKSQL-TINDNQKYPMMSVYKLHVAMALLDYME +KNNLSMNTEIHIKKEDLLPYSPLRDKHPEGNIPISELLKYTVSQSDNNTCDILFDYIGGP +ETVETYIKGLGIENIAICCNEKAMTENPDAVYTNWTTPSEAIKLVELFRAKNLFSPEYND +YLKTILIETTTGPNKIKGLLPEHLTVGHKTGNSSRNADNDVGFVTLPNGSGYSVAIFIKD +SKENDETNAQIISRISRVIFENy +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter rigui TaxID=1708790 RepID=UPI000F7EAB95 +----DATIARIADGSAGRIGVYAVDLASGREV-SVLGDQRFPMASTSKIAIAATFMEGVE +RGRFTLTSEFPLMVPVASKFSSAKAPVVPGKYKAVDLIEMMITRSNNQATDALLAAVGGT +SVVNDWARRNGIANFNLTRDIATLVRARTVDIRDSATPEAMVRLLTGLYQGKFLAESSRK +VILGAMGRCRTGTHRMRAMLPDDARVAHKTGTLSN-TASDIGIINTPDGRAIAVAIYVTG +QG-SREARDAKIASIARALYDGy +>[subseq from] Beta-lactamase n=1 Tax=Nostoc linckia NIES-25 TaxID=1091006 RepID=A0A1Z4L9V3_NOSLI +---LKNTVQNLATSNNLTPGVFLVDLDTGNYV-DINASTSFPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMQQEAIAGGSGNLQKAPGTQYAALEVATKMITISDNTATNMLITRLGGI +DALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSMPSRD +LMLDILRRTQR-DSLLPSGLGTGARVYHKTGDIGT-MLADAGLIIVPTGKRYVAAVMVQR +PNND-PRAEKLISSISRAAYQEf +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=A0A0N0IYK7_9FLAO +--TLTQKIENIISGKKADVGVAVIGIQKNDKV-QINGKKLYPMLSTFKFPIALTTLHQVE +KGRLKLDQKLFIKKEELLEWSPFRDEHPEGNITLEEALRWMMCYSDNNLTDVIIRLIGGT +EPVQKLIGG----DFIIKNDEEGMHKDWDSQFINKITPDKAADLLEKFYQGKILNPAHTQ +WLYNAMLNNQTGLKRLKGKLPANVKVAHRSGTSFTGAVNSYGIIELPHNRKIVVAVFVHD +TYESFDNAEAIIADISRTAYDHy +>[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B455F34 +--TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSNERFAYASTHKALAVGVLLQKKS +--IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP +SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSIEKRN +LLIDWMKRNTT------------------------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Novosphingobium sp. 12-64-8 TaxID=1970404 RepID=A0A257W248_9SPHN +--AIQQQVEAIVAQGRGRIGVAAMDLDGGGMV-LINGDQPFPMASCAKIAIAATYLDGVE +QGRLRLDQSFPMMMPVAQPRTSVAPVRAGTIMAAQNLMELSITRSDNHATDGLIAAVGGI +ATVNSWLTRNGIAGQRLDHTMATLVRATTIDTRTSSTPRAMIALLSAIDRGNALSPQSRA +VLLDTMTRTSTGRNRIRAGLPEGTLLAHKTGTLA-GVTDDVGIVRLPDGRHLAIAIFVTG +PEG-HTAHAGIISQVARVLYDGy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A6A1JVL5_9BACE +--SLETQLKEAIKDRKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA +KRNQSLDTLLKIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP +DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNRSTPLAAAELMEIFRREPLFAQEYKD +FIYQTMVECTTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEESFAENSKIIADISRIVYEY- +>[subseq from] serine hydrolase n=1 Tax=Nostoc linckia TaxID=92942 RepID=UPI000BBC2846 +---LKNTVQNLATSNNLTPGVFLVDLDTGNYV-DINASTSFPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMQQEAIAGGSGNLQKAPGTQYAALEVATKMITISDNTATNMLITRLGGI +DALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSMPSRD +LMLDILRRTQR-DSLLPSGLGTGARVYHKTGDIGT-MLADAGLIIVPTGKRYVAAVMVQR +PNND-PRAEKLISSISRAAYQEf +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. TaxID=1874826 RepID=A0A3D1P461_9SPHN +--NFEAQLYSAADASNGRIGVAMIDLTSGKTT-AVLGDTPFPMASTSKIAIAATFLDGVD +KGRWSLDDQFPLMIPVKSAFSGDKAPVRAGRYTARELIELSLIHSSNPATDALLAAVGGP +GSVNRWIRTTGIDGMRIDRDIATLVRATTVDLRDSATPVAMAQLLSGLFQGRWLSSRSRA +FLLSTMERCQTGKRRMRSLLPGDARVAHKTGTLNN-TASDVGIIQAPDGHAYAVAIYVTG +QGG-HAGRDARIASIARTIY--- +>[subseq from] Beta-lactamase n=1 Tax=Legionella sp. km488 TaxID=2184757 RepID=A0A317U8N9_9GAMM +--ELIKKLRAIEKNSNTVMGLTAIYIEKNKII-EHNSSERFFMASTIKLPIAMAFLHRVD +EKKDSLDRVIKMDSRNSVPGSGALHYLFEKKISLKQILMYTLKNSDNSASDALLQAASGP +KYVAKRMSALGFKNTYINRSIMEMFLRFQKDIRDTTTPDDMAKLLVKLYKKQALSESSTD +LLMKIMEQCRTGRSRIKGLLPPNVKVAHKTGTWSYRFVSDVGIITLPNKGHIAIAVYVKS +KSASDYPRSRAIALASRAIYDHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis terrae subsp. terrae NBRC 15098 TaxID=1219058 RepID=A0A142VW12_9SPHN +---LSDRISQLWRTFPGKTGIAVQRIDGEWSF-SERGGELFPQQSVSKLWVAMTVLDAVD +QGKLSLDRRVDIGPNDLTLHQPLAARVRSEGMSVRDLIETAITHSDNTANDSLLRTVGGP +EAVRRFIAKKDLGSIRFGPGERLLQSAYLANPMDGAAPAAIASALTRLARGALLSPESTQ +YLMSVMSRTRSGPKRLKAGLPSGWDFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGD +TSASIPARMALMQAVSGAVAE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0R5RPQ8_9BACT +-kELEQQIGQVLKDKKATVGVAVLANDTIVA--LHNNQIHFPLFSVFKFHVALAVLDKMD +KGHVSLDSIMEIKAAQMLPYSPLRQKFPDRDISLGELLKYSISLSDNNACDVLIDYVGGI +DKVNSYIKSLGLKDFNLAANEDLMHRDVATQCQNWSTLEAVVRLLNIADKQTLFAAGYKD +FLWQILKETSTGTDKLKGELPPDVIVGHKTGSSDKTADNDAGFIILPDGRKYYITVLVME +SQETDRENAAIIARISKIVYD-- +>[subseq from] Beta-lactamase family protein n=1 Tax=Bosea sp. RAC05 TaxID=1842539 RepID=A0A1B3NLV6_9BRAD +--RLSREIVAIEREAKGRLGVALLDLKDRSLW-SHRGGERFPMQSVFKWPLAIAALQAVE +AGRLWLDQPITIRRREFSLHSPLAKAFKGEAYPVRELIALAAGESDNTAADILMREIGGP +QAVTAMLKAGGITGISVDRYERQFQPLALRDSRDSATPEASVAFVEAQAKGNWLREPAHS +ALIDITLETKSGPDRIRAGLPQGARFAHKTVAGLNHATNDIGLVTLPNGRVFAIAVYLAG +STADAKQREAAHAAVARLAVA-- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingopyxis terrae TaxID=33052 RepID=A0A1Y6FQE3_9SPHN +---LSDRISQLWRTFPGKTGIAVQRIDGEWSF-SERGGELFPQQSVSKLWVAMTVLDAVD +QGKLSLDRQVDIGPNDLTLHQPLAARVRAEGMSVRDLIETAITHSDNTANDSLLRTVGGP +EAVRRFIAKKDLGSIRFGPGERLLQSAYLANPMDGAAPAAIASALTRLARGALLSPESTQ +YLMGVMSRTHSGPKRLKAGLPSGWEFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGD +TSASIPARMALMQAVSGAVAE-- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000C6E4098 +--ELLEKINTITKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKNAKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGIIAQVSKIVWDA- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium frigidarium TaxID=99286 RepID=UPI0009FEA965 +---LEKEINQIIANKKADVGVAILGIEDNFSL-QINGNKQYPLLSVFKFHLALAVLDKVD +KGIFTLDQKITVKERDLLEWSPFLKKYGKRDITMREALQWTISHSDNNICDVLIAKIGGI +NAINEFLNS---PHLILKNNEKQMHESWDAEFVNTTTPNYTAKLLKDFFENKIISNQATH +FLYKTMVETSVGLKRIKGQLPTNTEVAHRTGSSSTGAINDIGIVQIPNGKHVVVVVFVHN +TTEEFAVGEQIIAAISKVTYNAf +>[subseq from] Beta-lactamase n=1 Tax=uncultured Dysgonomonas sp. TaxID=206096 RepID=A0A212JKL1_9BACT +---LRNDIAKIIGGKRATVGVALI-VDGKDTL-TVNNEFHYPTQSTYKFHLALAVLDYLD +KNNLSLNHKIFIPKAELLPHSPLRDDYPDGNLSISEILKYTVSLSDNNGCDILFRFVGGP +SAVDQYIRSLGFTDFAIAATEEEMHGPWEVQYTNWSTPLTAARVLEKFRTGNILPQHFHD +FLWNAMVDTPTGPKKIRGLLPPGTIVAHKTGASFNAAENDIAIIRLPDGRYYSLTVFVAD +SMEDEATNMRIIAEISKAVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium GWC2_64_44 TaxID=1797935 RepID=A0A1F9TGA9_9BACT +------GLEKHSRSYRGRVGIYIKDLETGKTW-DYNSERQFPSASLIKVPIMAAVFEKIK +AGSLSLDTQIRLTRGGRVGGSGSLKWVRDGTLSVMEIIYKMITESDNTATKMLIDTV-GM +DYLSASFRALGLERTNITPEGMSLSSR-PVRRENYTTAREMGSLMERIYAGELVSREASE +FMLDVLKHTKS-RTRLRKGLPLGWEIGHKTGLLRR-NCHDVGIVFSPRGD-FVIAVLTSE +AP-NYTVAKNFIAKVAKLTYQYy +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. SCN 68-10 TaxID=1660098 RepID=A0A1D2RMZ9_9SPHN +---FEQRIAEIANPARGRIGVAAVDLTTGEEI-MVLGDQLFPMASTSKVAVAATYLDMVD +RGQFTLTSEFPLLLPVASASSPKAPVRPGNYMTAIDLIEIMITRSSNPATDALLAAVGGP +GNVNAWMRRHGFSDFSINRDIATLVRATRIDPRDAATPRTMVKFLSALYRGEFLQPQSRQ +VLLGALSRTVTGKRRIPAMMPVGTRVSHKTGSLNN-TSSDIGIIECPDGRVIAVAIYVTG +QG-TRAAREDKIAEISRALYDGf +>[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter sp. AAP60 TaxID=1523423 RepID=A0A0N0JQ15_9SPHN +---FEQRIAELANPAQGRIGVAAIDLATGEEV-MVLGDQLFPMASTSKIAVAAAYLEMVE +QGRYSLTSEFPLMLPVASAYSSAKAPVRAGQMPAIDLIEIMITRSSNPATDALLAAVGGP +ANVNSWMRRQGIHDFSINRDIATLVRANHIDTRDAATPRAMAQLLAGLYRGEYLSDQSRS +VILSAMSRTVTGKRRIPAHIPMEARVSHKTGSLNN-TSSDVGLIECPDGRTIAVAIYVTG +QG-TRAAREARIAAIARALYDGf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0013E40554 +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNAVS------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. StRB126 TaxID=878220 RepID=A0A077KLI7_9FLAO +-pDLTKTLQSIISNKKSDIGISIIGPYKNKIT-QINGNKLYPMLSTVKFPIALTVLHKIE +KGELSLEQKLFIKKEELLEWSPFKKEYPEGNISLEEAMKWMVSYSDNNLTDILLRLIGGP +EAVQKFINNKG---VIIQNNEEDMHKDWKSQFVNKITPNEAIKLLEAFYTQKILNKEHTK +WLYTAMLNNATGTKRLKGKLPKEVKVAHRTGTSFTGAVNDYGIIELSDKKRIYIAVFVHD +TYETFENSEAIIADIAKATYDYy +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura darangshiensis TaxID=705336 RepID=A0A4R5B021_9ACTN +------------GRLGGTLGVVAHDLGTGERA-AAGADRRFAAASVIKLPILLAVLAEAE +AGGRSLDDRLAAPPDARVGGSGVVKDLADAAFSVRDLLTLMIIVSDNTATNLLIGMV-GM +DAVNAWCARHGLHGTVLARVMMDAAA-RERGEENLTTPADIAALLTGLVRGELLGERATA +RALDVLSRQQL-NDRLPRHLPAGVTLAHKTGELA-GVCHDAGIVLPGDRAPIVVVAMTEG +IE-NEHDAAALISDTGRALYA-- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium nakagawai TaxID=1241982 RepID=A0A3N2F748_9FLAO +--QLKKTLESIITNKKADIGVAVLATDSKEIV-EINGNKLFPMLSTFKFHIALAILNKVE +KGDLSLQQKIYIKKEELLEYSPFKEKYPEGNLTLEECIKWMVAQSDNNLTDILLRLIGGP +EYVERFLNS---KDVIIKNDEEGMHKDWDSQFINKTTPNETIRLLGQFYNGKILNKELTK +WLYTTMLGNVSGAKRLKGHLPKEVKTAHRTGTSFTGAINDFGIIELSDKKRIYIAVFVHD +TYETFENSEAIIAAIAKAAYDHy +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus panacihumi TaxID=497735 RepID=A0A3M8CRG1_9BACL +---WQQAIDEVLREARGEFGVAVTHLESGMTA-GHQADQLFQMASVFKIPIIATLMRDVE +AGKIRLDQRIPLRYEERVPGSGVLQELDSGALTVKDLAMLMTIVSDNYATDMVINLV-GL +ENIEAHMRELGLESIHLPQTCWQLLNAAPTTENNVATPADLNRLLTMVAKKEILSAASCD +LILDILRRQQY-NSRLPLLLPPGTKVAHKTGTVN-GVVNDAGIIYLPEGGSIAISVLSRK +VE-EKQEAERTIAKVARAVYDQ- +>[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=UPI0007869DC8 +--TLTQKIENIISGKKADVGVAVIGIQKNDKV-QINGKKLYPMLSTFKFPIALTTLHQVE +KGRLKLDQKLFIKKEELLEWSPFRDEHPEGNITLEEALRWMMCYSDNNLTDVIIRLIGGT +EPVQKLIGG----DFIIKNDEEGMHKDWDSQFINKITPDKAADLLEKFYQGKILNPAHTQ +WLYNAMLNNQTGLKRLKGKLPANVKVAHRSGTSFTGAVNSYGIIELPHNRKIVVAVFVHD +TYESFDNAEAIIADISRTAYDHy +>[subseq from] serine hydrolase n=1 Tax=Moorea producens TaxID=1155739 RepID=UPI0010562789 +---LQKQIQTLVKQHQLQPGIFIHDLDTGAFL-ESNSRLIFPAASTIKLPILIAFFQDVD +AGKVLLDEYITMKPEMIAGGSGNMQQKPGKQYKALEVATKMITISDNTATNMLIERLGGI +EVLNQRFRSWGLKKTVLRNPLPDLPGT------NTTSPRELASLIFNLEQGKWISPQSRT +DLIDIMIQTKT-NTLLPQGLGNGATIAHKTGTLGR-LLADVGLVKMPNGKRYIISVMVKR +PFND-ASAEKLIRTISRQVYDYf +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00053108D9 +--ELLEKINTITKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGIIAQVSKIVWDA- +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. H071 TaxID=1759078 RepID=A0A0W1GS49_9SPHN +---LSDRIYALWRAYPGRVGIAVQRIDGEWAI-AQRGPDLFPQQSVSKLWVAMTVLDAVD +NGRLSLDQRVRIGPEDLVVHQPLAARVRAEGMSVRDLIETAITHSDNLANDSLLRTVGGP +EAVRAFLRKKDLGSIRFGPGERLLQANYLANPVDGASPSAIASGLTRLARGTLLSPESTD +YLLGVMSRTKSGPKRLKAGLPAGWQFVHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGS +TASPIPARMQLMQAVSGAVAE-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=uncultured Bacteroides sp. TaxID=162156 RepID=A0A1C5TVV5_9BACE +-sQLKTLLEQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQAVALADYMD +KKKLPLGTLLSIKKSDLKPYSPLRDQFPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DSVNRYIQSLGIRDCEITHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRRKTLFDEAYKD +FIYQTMVECQTGQDRLVALLDKGITVGHKTGTGDFNGCNDIGFILLPNGHAYSIAVFVKD +SAESSLENSKIIADISRIVYKY- +>[subseq from] Putative beta-lactamase n=1 Tax=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / NCTC 11153) TaxID=411476 RepID=A7M5B8_BACO1 +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTI-TVNNDIHYPLMSVFKFHQALALADYMG +KQGQSLETRLAIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP +DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLDKKITVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANSKIIADISRIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SZ45_9BACT +---------SLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI0009B8EB74 +-----KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNRP +--TSELNKKIAISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIDGI +KEFQQALIHRGDHISNPQRLEPDLNLYDPQSTDDTTTPKRAATTFNHLLQSENMSKANLE +LLKHTMIHNETGGTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK +SDKDAKPDDKVIQTAAETAIK-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis sp. MWB1 TaxID=1537715 RepID=UPI000519F88A +---LEDRLFQLWRTFPGKTGVAVQRIDGEWAL-AQRGDDLFPQQSVSKLWVALAALDAID +QGRLSFDRSVRIGPDDLTLYQPLAARVRAEGMTVRELIETAITRSDNTANDKLLWTIGGP +DTVRSFIRKNDLGAIRFGPGERLLQSRYLADPVDGASPAAIAAALTRLARGELLSAESTS +YLLDVMSRTRSGPQRLKAGLPPGWKFGHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGN +TTASVPERMSLMQAVSGAVAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides finegoldii TaxID=338188 RepID=A0A174G8M5_9BACE +-sQLKTLLEQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIQYPLMSVFKFHQAVALADYMD +KKRLPLGTLLSIKKSDLKPYSPLRDQFPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DSVNRYIQSLGIRDCEITHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRRKTLFDEAYKD +FIYQTMVECQTGQDRLVALLGKGVTVGHKTGTGDFNGCNDIGFVLLPNGHAYSIAVFVKD +SAESSLENSKIIADISRIVYKY- +>[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia anophelis 502 TaxID=1355388 RepID=T0NFH1_9FLAO +--ELLEKINTITKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=UPI00099A3859 +--ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNKVD +RGNLALDQKILVKKSDLLEWSPIREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGV +KTVQKLMDVNGVKNFQVKYNEEEMHKNVKALYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGISKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQISKIVWDT- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides xylanisolvens XB1A TaxID=657309 RepID=D6D2E6_9BACE +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLETRLPIKKSDLKPYSPLRDKYPQGEMSIADLLKYTLQQSDNNACDILFDYQGGP +DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPNVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKN +SEENNQVNSKIIANISRIVYEY- +>[subseq from] Uncharacterized protein n=1 Tax=Parabacteroides gordonii MS-1 = DSM 23371 TaxID=1203610 RepID=A0A0F5IVP1_9BACT +-kELEKQLQEAIANKKAQVGIAII-INGKDTV-TINNNCRYPMMSVFKLHQALAVADYCQ +KNGISLDTPVYIRQADLKPYSPLRDKYPEGDLSIKELLEYTLLLSDNNACDILFAQAGDT +KSTDNYIRSLGLRDFSIKVTEDEMHQNESTCYENWSTPLETAKLIELLVTKELFNKESQE +FIKRTMISCETGKDRLPLPLMTNAIIGHKTGTGDRNGTNDVGFVYLPNRQRYTIAVFIKD +SEESEKATSEIIADISRIVYQY- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. 1_F178 TaxID=2258962 RepID=A0A3D9C9N5_9FLAO +--QLKKTLESIITNKKADVGVAVLATDSKEIV-EINGNKLFPMLSTFKFHIALAILNKVE +KGDLSLQQKIYIKKEELLDYSPFKEKYPEGNLTLEECIKWMVAQSDNNLTDILLRLIGGP +EYVERFLNS---KDVIIKNDEEGMHKDWDSQFINKTTPNETIRLLGKFYNGKILNKELTK +WLYTTMLGNVSGAKRLKGHLPKEVKTAHRTGTSFTGAINDFGIIELSDKKRIYITVFVHD +TYETFENSEAIIAAIAKAAYDHy +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. Root1497 TaxID=1736474 RepID=A0A0Q7Z6X9_9SPHN +---LDDRIFQIWKAFPGKTGIAVQRIDGEWTL-AQRGAELFPQQSVSKFWVTLTVLDAVD +NGRLSLDQKVRIGPEDLTVHQPIAARVQSQGMTVRDLIETAITHSDNTANDSLLRTVGGP +DAIRRFIDKKDLGAIRFGPGERLLQAAYRANPPDGASPVAIAGALTRLARGTLLSSESTQ +YMLGVMSRTKSGPQRLKAGLPAGWTFLHKTGTGQTVGYNDIGIATAPDGTRYAIVVMMGE +ATSPIPARMATMQAVSRAVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides cellulosilyticus TaxID=246787 RepID=A0A412IKK9_9BACE +-qEIEQQIDSLLKEKKATVGVAVLA--NGETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI +DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKHPLFGTQYKD +FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQENDADNAAIIASISKIVYDT- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A349TB77_9SPHN +-tSLERRIAQLADGDKGRIGIAAIDLATGREV-SVLGNQLFPMASTSKIAVAAAYLEIVE +QGKYSLTSEFPLLIPVRSASSPAAPVRKGEYMAAVDLIEIMITRSSNPATDALLAAVGGP +AKVNDWVKRQGIEEFSIDRDIATLVRAYHIDDRDAATPRAMAELLQGLYQGKFLSAESRE +VILGAMSRTVTGKRRIPALMPEEAAVSHKTGSLRN-TSSDIGIIEAADGRAIAVAIYVTG +QG-SRRNREDKIAMIARAVYDGf +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. GV010 TaxID=2135477 RepID=A0A2V5BA41_9SPHN +---FEARLAAVANASHGRIGVAAVDLSNGKGI-SVMGDQPFPLASTGKVAIVATFLDGVD +QGRFRLTDRFPIMMPTYSRGSGPAPQRAGALYSATQLIDMAIIHSNNHATDALLAAIGGP +GAVDRWLRKSGIGGIRIDRDIATLVRATTIDLRDSTTPQAMATMLAGLYQGQWLSPNSKA +VLLSAMGRCATGSHRIRGLLPSDAIVGHKTGTLNN-TSSDVGIIRTADGRNIAIAIYVTG +QG-SKPGRDSRIASIARTVYEGy +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium HGW-Alphaproteobacteria-14 TaxID=2013660 RepID=A0A2N3DAZ3_9PROT +--SFEQRIAELANAEQGRIGVAAIDLATGEEI-MVLGDQLFPLASTSKIAIGAAYLEMVE +QGRYSLTSEFPLMMAVRSASSPKAPVREGQYMPAIDLIEIMITRSSNPATDAMLAAIGGP +AVVNNWMRRQGINDFSINRDIATLVRATHIDPRDAATPRAMARLLAGLYRGDFLSDQSRQ +VLLGAMSRTITGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGIIETPDGRAIAVAIYVTG +QG-TRLAREQRIAAIARALYDGf +>[subseq from] CME family class A beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=A0A1A6CIU4_ELIMR +htSILNDINAVTKDKKATVAVSVLGIENEFQFsNTNGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPNGNIPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKDIKALYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMTKLPGLLP-KVKMARKTGSSGTVAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQISKIVWDT- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI0003F4BFD5 +--ELLEKINTITKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] Beta-lactamase n=2 Tax=Novosphingobium sp. AP12 TaxID=1144305 RepID=J2GAY8_9SPHN +-----QQLAAVANASQGRIGVAAMDLSSGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD +KGKWSLSSEFPLMVPVGSASSAIAPVRAGEYMTASRLIELMITRSNNYATDALLKVVGGP +KAVNAWVERAGIDDWHIDRDIATLVRARVVDNRDSATPYAMVKLLSGIYQGKWLSPSSRG +VIMGAMSRCVTGKRRIAAGLPADASISHKTGSLNN-TSSDVGIIQTPDGRVFAVAIYVTG +QG-GRPGREARIASIARTIYNGy +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacteraceae bacterium CFH 75059 TaxID=2528174 RepID=A0A4R0NSX5_9SPHN +--DLQQRVAALAEPSRGRIGVMAVDLSTGQEV-AVLADQRFPMASTSKIAVAATFLEGVE +QGRWTLSSEFPLLRQSARFSSAVAPVTQGRYMPAIDLIEIMIARSSNPATDALLAAVGGP +GVVSNWMRRNGITEFSLDRDIATLVRAIHVDVRDSATPRAMVTFLRGLHEGHYLSPTSRQ +IILGAMSRTVTGQRRIRALMPMNAQVAHKTGSLNN-TSSDVGIVTLPDGRAVAMAIYVTG +QG-TRLEREAKIASIARVLYDGf +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=UPI000999187B +--ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKNVKALYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMTKLPGLLP-KVKMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQISKIVWDT- +>[subseq from] Beta-lactamase n=1 Tax=Parabacteroides sp. AF18-52 TaxID=2292242 RepID=A0A3R6RPG9_9BACT +-eQLKADIQEIIKDKKARIGVGII-LNGKDTV-TVNNEDRYPMMSVFKFHQALAVLNYLQ +QNNLPLDTQIRMEKEDIIEYSPLRDKYPQGNLPISELLKYTIQLSDNIACDVLFKYIGGP +SVADKYIRSLGLQQFSIVITEDDMHLDLSACYLNWSTPLEAARLLDILLTRSLFKEEYQE +FIKNIMIECETGKDRLPQLLKTKAVIGHKTGTSDKGGTNDIGFVLLPDGSRYTVAVFIKD +SNESMETNAKIIASISDVIYKY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis witflariensis TaxID=173675 RepID=A0A246JUN6_9SPHN +---LNDRITQLWKAFPGKTGIAVQRIDGEWAL-SQRGEDLFPQQSVSKFWVALSILDAVD +QGRIRLDQPVRIGREDLTLYQPLAARVQAEGMSVRELIETAITHSDNTANDSLLRTVGGP +EAVRRFISKKDLGAIRFGPGERLLQSAYLANPVDGASPAAIASALTRLARGTLLSPESTE +YLLDVMSRTRSGPRRLKAGLPPGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGS +TTSPIPARMALMQAVSGAVAE-- +>[subseq from] Serine hydrolase n=1 Tax=Armatimonadetes bacterium TaxID=2033014 RepID=A0A351AFF0_9BACT +--ATEAQLAAIEARSQGKLGAAVV-TAQGAHY--LHRDGKFSLQSVMKLMVAMAAVEQVD +RGQWRLDQSFEFKRSDLSLHQPITQRLGRRAITLDECIELMVTESCSGAAEFIIRRLGGP +QAVNAFLVKHDIQGMRIDRQERDLQTRYLADPRDTTTPAAMAKLLQKLLKGQLFSPKSTR +YLLGVMERTATGQDRLRAGVPKGWTLGHKTGTSSAGATNDVGIARNKAGEWVILVALLRE +STLAPRDRDRILADVARA----- +>[subseq from] Beta-lactamase n=1 Tax=Legionella steigerwaltii TaxID=460 RepID=A0A378LCB4_9GAMM +--ELIKKLNAIEKKSNTIMGVTAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD +EKKDSLNRVIKMDSRNSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP +KYVAQRMSALGFKNIFINRSIMEMFVRFEKDTRDTTTPNDMAKLLVKLYKKQALSESSTN +LLMKIMEQCRTGRSRIKGLLPPHVKVAHKTGTWSYRFVSDVGIITLPNNGHIAIAVYVKS +KSASDYPRSRAIALASRAIYDHf +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis R26 TaxID=1246994 RepID=A0A290NA07_9FLAO +--ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. Chol11 TaxID=1385763 RepID=UPI000BE2C306 +---LLGEFSRFASLSDGTVGIAVRDLRSGETL-ELNGDTLFPMASTYKVAVAGKILSLAD +AGMLRFDEKLP---------------RLGTAMPVTALLDLMLTRSDNEATDALVARAGGP +QAVNGWLQSLGIRGQRVDSNTAQLLAAFAADPRDTSTPRAMNDLLSTIQHGKALKRDSTA +MLLGIMARCKTGKARLVGMLPPGTPVAHKTGTLN-GLGNDTGIITLPDGRPIAISVFVMK +DHRGHAARDRIMAEVARAAYDYf +>[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=A0A1T3E5Q7_9FLAO +--ELLEKINTITKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEDVNCGIIAQVSKIVWDA- +>[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=A0A1T3DUB6_9FLAO +---LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEDMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. HME9302 TaxID=2161824 RepID=A0A369Q7T2_9SPHN +-tALEQRIAQLADGSAGRIGVYAIDLASGEEV-SIMGDQRFPMASTSKVAIAATFLAGVD +AGRWSLTSEYPLLRPVRSAYSSARAPVRNGNISARKHLDLMISKSCNSCTDALLRVVGGP +EAVNAWMRGAGISEFELTRDIATLVRASMVDRRDSATPRAMGQLLAGIYQGRLLSANSRS +VLINAMKKTTTGKNRMVAALPAYANVAHKTGTLNR-TASDIGYFDTTDGRTIAVAIYVTG +QSAARSKRDRRIADISRALYEGf +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A0J7XZT9_9SPHN +--KLLGEFARFAALSDGSVGIGVRDLQTGETQ-ALNGDTLFPMASAYKIAVAGRIFALVD +AGQARLDEQLALDPALASEGIAWMFSRPGATLSIDRLLELMLQKSDNNATDVLVARAGGP +QAITGFVNKLGVTGLRVDSDTAHLLYAFAAELQDTSTPAAMLDLIAAYESGRALSAASTQ +RLFTIMANCETGKKRIVGMLPPGTAVAHKTGSLN-GTGNDVGVVRLPDGRRFAIAVFVMK +DSKGHVARDRIIAEAARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. TH158 TaxID=2067455 RepID=A0A2N4X609_9SPHN +---FEASIAALAEGSQGRIGVAALDLDSGRAV-TVLGEQAFPMASTSKIAIVATFLAGVD +EGRFKLYDQYPLLVPVPSKKFSSAQAPVRQGMSALSLIEATITRSDNQATDALLAAVGGP +HAVTRWVHSTGITDFRIDRTIATLVRAVSIDKRDSVTPLGMVRLLSGIYRREWLSPMSSD +VLLGAMSRTVTGKHRIRGLLPQGTQVAHKTGTLSN-TASDVGFIKTPDGRNLAVAIYVTG +QG-GKPQRDARIAAIARALYDGy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D5CA65_ECOLX +-------------------------------------------------MAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGS---------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. XM-24bin4 TaxID=2133952 RepID=A0A316JWK4_9SPHN +--SFERRIAQLADGSRGRIGVAAINLNTGEEI-AVLGDQLFPLASTSKIAVAAAYLELVE +QGRYSLTSEFPLLIPVRSASSRAAPVREG-NMPASELIEIMISRSSNPATDALLRVVGGP +AAVNDWMRRQGIKEFSINRDIATLVRSAHIDTRDAATPKAMVELLQGLYQGKFLSAQSRQ +VILDAMAKTRTGTRRIPAEMPDYVQVMHKTGSLNN-TSSDIGILEGPNGHAIAVAIYVTG +QGAR-GAREARIASIARALYDGf +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter lappiensis TaxID=354630 RepID=A0A1N7G0R8_9SPHI +-qSIRQQVIKIASGIKAQVGVSAMIVETGDTV-NYHAGDKFPMQSVYKLPIAIAVLHQVE +LGRLSLNQKVKVSPAEIIPVSPIRDHYPHGVLSILELLRYNISDSDGSACDVLIRILGGC +QKINQYIHGVGIRDIAISTTEMVQVSDDWVQYRNWVKPEAMLLLLKKFYAGLLLNRSHNE +LLLNLMIKSGPGAKRLKGMLPAQAVVAHKPGSSGTRATNDVGIVTLPNNKHLLIAIFIAD +TYADTEEREGVIAQITKTAWDTw +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. FF12 TaxID=1608584 RepID=UPI0006D85723 +-aELKKEISKITLGKKATVAVSVLGIDFPFQYnNENAEKKLPMQSVFKFHIALAVLDLVD +QGKLSLDQTLFIKKSELLPWSPIREKYPDGNITLAEALKWMVAESDNNCTDIILRLIDGT +KTVQNFLDKNKIKNTQIKFNEEDCHKILNLQYQNYTTTKSANNTLKVFFDKELISKNSTD +FLYKLMVETSTGKNRLVAGIPKGTEIAHRTGTSFTEAVNNIGIVTLPNEKKYAISVFVSD +SKENFDVNEKIISDISKVVFENf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=C3VJV0_STAAU +---HAKELNDLEKKYNAHIGVYALDAKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQA--------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. CDS-1 TaxID=2004404 RepID=UPI000B3C025D +--RLMAEFARFSTLTDGTVGIAVRDLGTGETL-AYNGDTLFPMASTYKVAVAAKILSLLD +AGSLSLDEPLL---------------RLGRPLPVRTLLEMSLTLSDNEATDALVARAGGP +QAVNDWVHAAGIKGLRVDSNTRDLLAGFTADPRDTATPRAMDDLLAAIRLGKLLKPQTTA +LMLSIMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDTGIITLPDGRIFVISVFVMK +DYKGHEMRDRIMAEAARAAYDYf +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia sp. 2-6 TaxID=2575699 RepID=A0A4P8E4T9_9FLAO +htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKDIKALYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMTKLPGLLP-KVKMARKTGSSGTVAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQISKIVWDT- +>[subseq from] Beta-lactamase n=3 Tax=Sphingobium TaxID=165695 RepID=A0A1L5BR14_SPHIB +------------------------------------------------------------ +----------------------------GRPLPVRTLIDMSLTLSDNEATDALVARAGGP +QAVNDWVRAAGIKGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGRVLRPQTTA +LMLSIMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK +DHMGHELRDRIMAEAARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TKS TaxID=1315974 RepID=A0A126RIS3_9SPHN +--RLMAEFARFSTLTDGTVGIAVRDLGTGETL-AYNGDTLFPMASTYKVAVAAKILSLLD +AGSLSLDEPLL---------------RLGRPLPVRTLLEMSLTLSDNEATDALVARAGGP +QAVNDWVHAAGIKGLRVDSNTRDLLAGFTADPRDTATPRAMDDLLAAIRLGKLLKPQTTA +LMLSIMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDTGIITLPDGRIFVISVFVMK +DYKGHEMRDRIMAEAARAAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium UBA11367 TaxID=2055774 RepID=A0A352XAB0_9CYAN +--ALTTKIQALAAQNKLQPGVLVVDLDTGNYL-DFQSNASFPAASTIKIPILVAFFQDVD +AGKIRLNESLTMEPDAIASGSGNLQQKPGTNYTALEIVTKMIAISDNTATNMIIKKLGGA +KALNQRFHDWGLRTTVINNPLPDLEGT------NTTNPKDLATLMFRVNEGELLSLRSRD +RLLNIMQQTVN-NSLIPQGLAPGAIVAHKTGDIGS-MIGDAGLVDMPSGKRYVIAIMVKR +PHND-TSASELIRQISRAVYQSf +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga dinghuensis TaxID=1539050 RepID=A0A327WDF0_9BACT +---LRDKIAQIIAGKKADIGVSVIGFQKNDTV-QFNGNQLYPMLSTFKFPIALTVLHKVE +KGELNLEQKVLIREAELLDWSPFKDEHPKGDLTLADAMRWMLCYSDNNLTDIILRLIGGA +MPVQQFI---GSKNFIIRNDEEDMHKNWDAQFINKITPNEAAQLLDKFNKGKILNAVHTK +WLYDAMVNNQTGLKRLKGKLPANIKVAHRSGTSFTGAVNSYGIIELPNHKKIIVAVFVHD +SYETFNNTEAIIADISKAAFDYy +>[subseq from] Beta-lactamase n=1 Tax=Scytonema sp. NIES-4073 TaxID=2005464 RepID=A0A1Z4PQD3_9CYAN +----KTVVQNLAAANNLTPGVFLVDLDNGSYV-DVNGSSSFSAASTIKIPILVAFFQDVD +AGNIRLDETLTMQKEMMVGGSGDMQKAVGTQFTAMEVATKMMTVSDNTATNMLIARLGGM +EVLNQRFQSWGLTTTAIRNPLPDLQGT------NTTSPKELGNLMAMVSKGNLVSMSSRD +RILDIMRRTVR-NHLLPTGLGPGATIAHKTGDIGT-TLADAGVVDMPTSKRYIVAVMVQR +PNND-SRAEKLISSISRAAYQQf +>[subseq from] Class A beta-lactamase n=1 Tax=Empedobacter brevis TaxID=247 RepID=A0A5P2GG98_9FLAO +-pELKQQIDQILLNKKADVGVSIIGSGKNDNI-QINGNKMYPMLSAVKFPIALAVLDKVQ +KGELAMNQHLFIKKEELLDWSPFKEKFPEGNITLEEALSWMVSYSDNNLTDILLRLIGGP +ETVQRYINS---KYFSIKNDEEDMHKDWESQFINRITPNEAVALLKKLDDGKLLNKTYTT +WLYTAMLNNQSGAKRLKAQLPKGVKIAHRTGTSFTGAINDYGIIELPNNQKIYIAVFVHN +TYESFPDSEKIIADISKAAFDYy +>[subseq from] serine hydrolase n=1 Tax=Fischerella sp. PCC 9431 TaxID=1173023 RepID=UPI000419D38A +--SLKTNLQSLASANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKVPILLAFFQDVD +AGKIRLDEMLTMEKEMMVGGSGDMRNKPAGTFKALEVANKMMTISDNTATNMLIARMGGI +EALNQRFRSWGLNTTVIRNQLPDLDGT------NTTSPKELGNLMAMVNQGNLISMTSRD +RILEIMRNTVR-NQLLPTGLGQGATIAHKTGDIGS-MLADAGLVDLPTGKRYIVAVMVKR +PNND-LSAEKLIGSISKATYQQf +>[subseq from] Beta-lactamase CME-1 n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=X5K7C3_9FLAO +--ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] serine hydrolase n=1 Tax=Leptolyngbya sp. 'hensonii' TaxID=1922337 RepID=UPI0009FABDA0 +--ALKTEVQALTAQNGLTAGVFFVDLDTGAYI-DLNGDSTFSAASMIKVPILVAFLQDVD +AGKIRLDEMLTMRPDLIGSGSGVIQYRTGTQFTALEIATKMIVISDNTATNMLIDRLGGI +AALNQRFQSWGLTGTLVYNLLPDLEGT------NVTRPKELATLMFRVSQGDLLSIRSRD +RMLDIMRRTET-DTLLPRGLDDNATISHKTGDIGS-MVGDVGVIDAPNGKRYVAVAMVKR +PHND-SRAQEMIRRISRAAYQAy +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter xinjiangensis TaxID=762261 RepID=UPI000F7ED0BB +-kNLQQQINQLGRQFDGKVGIAVRDVQSGWTA-AYNGREWFPQQSVSKLWVSLTALDQVD +KGKLNLSKEVTVERKDLAVFQPIRTLVLRDGTTLDDLMERAITRSDNTANDFLLWRTGGP +HAVQDTLADKNIKGIRFGPGERLMQSDYIADPVDGATPVGMVNALARLKQGKLLSSESTE +KMLDILHETRSGPRRLKGGVPGGWKIGHKTGTGQQAGYNDVGIVTAPSGNSYAVAVLIGR +TSVPLPQRMDMMQRTVRAVVNY- +>[subseq from] Uncharacterized protein n=1 Tax=Sporolactobacillus terrae TaxID=269673 RepID=A0A5K7WVX0_9BACL +---TDQAFVQLEKKFDARIGVYAFDSGTQRTV-AYRPDDRFAYASTYKALAAGAVLQQSS +--IHQLNEVILFSKDDLVTYSPIAENRVNSGMTLGEICEAAIRYSANTAGNLLLKKLGGS +NGFEKTLNKIGDNVTKANRFETDLNEAIPGDLRDTSTASALATDLKAFSVGKAPPTHKRK +MLADWMRGNTTGDQLIRAGVPKG------------------------------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Moorea producens 3L TaxID=489825 RepID=F4XTV7_9CYAN +---LQKQIQTLVKQHQLQPGIFIHDLDTGAFL-ESNSRLIFPAASTIKLPILIAFFQDVD +AGKVLLDEYITMKPEMIAGGSGNMQQKPGKQYKALEVATKMITISDNTATNMLIERLGGI +EVLNQRFRSWGLKKTVLRNPLPDLPGT------NTTSPRELASLIFNLEQGKWISPQSRT +DLIDIMIQTKT-NTLLPQGLGNGATIAHKTGTLGR-LLADVGLVKMPNGKRYIISVMVKR +PFND-ASAEKLIRTISRQVYDYf +>[subseq from] Beta-lactamase n=3 Tax=Sphingobium TaxID=165695 RepID=A0A081SYL5_9SPHN +------------------------------------------------------------ +----------------------------DRPLPVRALIDMSLTLSDNEATDALVARAGGP +QAVNDWVRAAGIKGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGRVLRPQTTA +LMLSIMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK +DHMGHELRDRIMAEAARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Dyella jiangningensis TaxID=1379159 RepID=A0A023NTV7_9GAMM +--RLQQALDTAARRAPGTLGLAVLDVRSGARA-GVRADEPFPMMSVFKAPVAAALLAQVE +QGSLSLAQEVTVTRADLRDGSAVPGAQVEAGFTIERLLQGAVSESDNTAVDALLRVMRGP +SVVTAFLRAHGIDGMRIDLDEGGISDAFLADPRNRSTPAAAVEFLRKLQGGELLSPASTQ +QLLRLMAGQTL-PNRLRAGVPQGVGFADKCGTSSTQAYNDIGIMTWPDGRIVIITAFLSD +SSASALQRDTLFADLARAVAA-- +>[subseq from] serine hydrolase n=1 Tax=Actinomadura montaniterrae TaxID=1803903 RepID=UPI00124EE75B +-------LVRRASRLGGTLGVVAHDLGTGERA-EVNAERRFTSASVIKIAIMATVLAEAE +AGGRSLDDRLPAPPDARVPGSGVIKDLADAAFSVRDLLTLMIIVSDNTATNLLIDLV-GR +DAVNAWCARKGLRGTVLARVMMDAAA-RERGEENVTTPADVAALLTGLVRGELLGERATA +FALDALSRQQL-NDRLPRHLPPGVTLAHKTGELA-AVCHDAGIVLAKGREPIVLVAMTEG +ID-SESEAATLIAETGRAAYT-- +>[subseq from] serine hydrolase n=1 Tax=Fischerella sp. PCC 9339 TaxID=1174528 RepID=UPI00030F6916 +--SLKTTVQSLASANNLTPGVFVVDLENGSYV-DINASASFPSASTIKIPILVAFFQDVD +AGKIRLDEMLTMEKEMMVGGSGDMRYKPAGTFKALEVANKMMTISDNTATNMLIARMGGI +EALNQRFRNWGLNTTVIRNQLPDLDGT------NTTSPKELGNLMAMVSQGNLLNMTSRD +RILGIMRNTVR-NQLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYILAVMVKR +PNND-PSAEKLIGSISKAAYQQf +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas jatrophae TaxID=1166337 RepID=A0A1I6KZZ1_9SPHN +---FLNSIQALGSGFAGDVGIAIRDVDEGWTV-AFNADTPMPQQSVSKLWVAITVMDAVD +RGTLSLNETVTVRRSDLTVHQPIRALIGPDGTTLHEILEMAMTRSDNTANDVLLRRVGGP +AAIRRMLADKGIARVRFGPGEPRLQARYLADPEDGATASGIADGLALLAQGRLLSPMSTA +NLLGLMRRSKTGPLRLRSGLPAGWSLAHKTGTGQSTGYNDVGLVAAPNGHRYAVAVLIAS +TRQPIPARMRLMGNVMRALVR-- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas sp. NFR15 TaxID=1566282 RepID=A0A1G5TZF8_9SPHN +--ALARSINAVARSFDGRVGVAVRSIDKGWTV-ESNGDVRLPQQSVSKLWVAMTVLDFRD +SGRLTLDDPITLTRNDLTLHQPVASLLKNGETTVGELLRRALTMSDNTCNDRLLRYVGGP +SAVRAFIARKGLGNIRFGPGERLLQSRYVADPPDGAAPRAIADALARLKKGELLSPTSTA +YLISTMESSKTGKQRMRGAVPPGWSFGHKTGTGQTAGYNDVGLLMAPDGRAYAIAVMIGD +TPRTIPQRQELMQSVVQAVVA-- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000999A808 +--ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPIREKYPDGNLPLSEIIAYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYNTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00099AB5BF +--ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KDNLTLDQKILIKKSDLLEWSPIREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] serine hydrolase n=1 Tax=Moorea producens TaxID=1155739 RepID=UPI0010FAAC08 +---LQKQIQTLVKQHQLQPGIFIHDLDTGAFL-ESNSRLIFPAASTIKLPILIAFFQDVD +AGKVFLDEYITMKPEMIAGGSGNMQQKPGKQYKALEVATKMITISDNTATNMLIERLGGI +EVLNQRFRSWGLKKTVLRNPLPDLPGT------NTTSPRELASLIFNLEQGKWISPQSRT +DLIDIMIQTKT-NTLLPQGLGNGATIAHKTGTLGR-LLADVGLVKMPNGKRYIISVMVKR +PFND-ASAEKLIRTISRQVYDYf +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. ATCC 43529 TaxID=1840705 RepID=A0A367QR98_9NOSO +----KNAVQNLATSNNLTPGVFLLDLDTGNYV-DINASTSFPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMQQEAIAGGSGNLQYKAAGTYAALEVATKMITISDNTATNMLITRLGGI +DALNQRFRSWGLTTTVIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSMPSRD +LMLDILRRTQR-NSLLPSGLGTGARVYHKTGDIGT-MLADAGLIIVPTGKRYVAAVMVQR +PNND-PRAEKLISSISRAAYQEf +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00077E88C9 +htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNQVD +RGNLALDQKVLVKKSDLLEWSPIREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGV +KTVQKLMDVNGVKNFQVKYNEEEMSKKVQAPYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=C6IKY5_BACT4 +--SLENQLKQAIQGKKAEIGIAVI-IDGKDTV-TVNNETHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DAVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGRAYSIAVFVKD +SEENNQENSKIIADISRIVYEY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=UPI000660DC08 +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DAVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLGKDVTIGHKTGTGDRNACNDIGFILLPDGHAYSIAVFVKD +SEENNQENSKIIADISRIVYEY- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=3 Tax=Elizabethkingia miricola TaxID=172045 RepID=UPI000B3630ED +--ELLEKINTITKDKKATVAVSVLGIENEFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKNVKALYANYTTTASMVKTLKAFYKGLFLSKRSTF +FLMDIMTKTNTGMTKLPGLLP-KVKMARKTGSSGTVAENDSGIVTLSNGKHYAIAVFVKD +SMESEEVNCGMIAQISKIVWDT- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium chlorophenolicum TaxID=46429 RepID=A0A081RGG0_SPHCR +------------------------------------------------------------ +----------------------------GRPLPVRTLIDMSLTLSDNEATDALVARAGGP +QAVNDWVRAAGIKGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGKVLKPQTTA +LMLSVMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK +DYRGHEMRDRIMAEAARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas vesicularis TaxID=41276 RepID=A0A2X1BCA7_BREVE +-------LSDLETRNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKMYLAAATLLRVQ +LGQERLDRRIPITAADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP +SAMQTFYRSIGDDSTRSDRVEPEMNRL--DGDKDTILPNQSVANLQRLFLDPALTAASRA +LLLQWMTDTPTGQNRLRAGTPADWRVAHKTGTGAMG------------------------ +----------------------- +>[subseq from] Beta-lactamase BlaZ-like protein n=2 Tax=Macrococcus canis TaxID=1855823 RepID=A0A0D6DR74_9STAP +--KINEDIKVIENKYNIQAGVYVNDLTDKQKL-SYNEERLFPYASTFKVINSALLIEKLG +--MNNLDKEVKVSERDIVLYSPIIEKYKNKNVSLKMLIEAALLYSDNTANNLIIEELGGL +KEVEKRLSALGINGANVNRKEVALNFYDPKKNEDTISAKNMSKVLTKMLTGDVLEYKEQI +FLIDLMKKNKTGTTLIKKGMDKKFIVGDKSGQGNYGVRNDIAVVYKKQSKPIIVVVFTKA +KNEKQKPSDTPIVEISKVI---- +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis macrogoltabida TaxID=33050 RepID=A0A2W5L4V7_SPHMC +---LSDRIAQLWRGFPGKTGIAVQRIDGEWSL-AERGDDLFPQQSVSKLWVVMTVLDAVD +DGRLRLDQSVRIGTEDLTLHQPMAPRVRAAGMTVRELIEAAVTGSDNTANDSLLRTVGGP +EAVRRFISKNDLGSIRFGPGERLLQSRYLANPVDGASPAAIGRALTRLARGTLLSPESTQ +YLMGVLQRTKSGPNRLKAGLPSGWTFGHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLAD +TTATVPQRMALMQAVSGAVAE-- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia bruuniana TaxID=1756149 RepID=UPI0011B6C567 +htSILNDINAVTKDKKATVAVSVLGIENEFQFsNTNGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKNVKALYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTRTNTGMAKLPGLLP-KVKMARKTGSSGKMAENDSGIITLANGKHYAIAVFVKD +SMESEEVNCGMIAQISKIVWDT- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=A0A415M2E0_BACT4 +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIAELLKYTLQQSDNNACDILFQYQGGV +DAVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD +SEENNQENSKIIADISRIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium barthaii TaxID=1054037 RepID=A0A4R6FGS4_9SPHN +------------------------------------------------------------ +----------------------------GRPVPVRTLLEMSLTLSDNEATDALVARAGGP +QAVNDWVHAAGIKGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLGAIRQGRVLRPQTSA +LMLSIMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDTGIVTLPDGRMFVISVFVMK +DHRGHEMRDRIMAEAARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia anophelis NUHP1 TaxID=1338011 RepID=A0A077EHW5_9FLAO +htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] Penicillin-binding protein n=1 Tax=Nostoc linckia z16 TaxID=1628751 RepID=A0A2C6VYB3_NOSLI +----KNAVQNLASNNSLTPGVFLVDLDTGNYV-DINASTTFPAASTIKIPILIAFFEDVD +RGKIRLDEMLTMQQDMIAGGSGNMQYQAAGTYAALEVATKMITISDNTATNMLITRLGGI +DALNQRFRSWGLTTTVIRNQLPDLQGT------NTTSPKELGNLMAIISQGNLISMPSRD +LMLDILRRTQR-DSLLPSGLGTGARVYHKTGDIGT-MLADAGLIVVPTGKRYVAAVMVKR +PNND-PRAEKLISSISRAAYQEf +>[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia anophelis NUHP1 TaxID=1338011 RepID=A0A077EDL2_9FLAO +---LKKTLESIISGKRATVGISIMGPDTKDVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQKFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNSAALLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDESEKIISDIGRAAYDYy +>[subseq from] Beta-lactamase n=1 Tax=Legionella drancourtii LLAP12 TaxID=658187 RepID=G9EPM0_9GAMM +--ELAKKIAAIEKKSNTIMGVTAIYIEQDKVV-THNSTQRFFMASTIKLPIALAFLHRVD +EKKDSLTRVIKLDAKNSVPGSGSLYHLFEKKMSLQQILKYMLINSDNSASDTILQAANGP +KSVAKRMGALGFKNISINRSILEILLRFENDMRDTTTPEDMAKLLVKVYKKEALSEASTD +LLLNIMAGCRTGRSRIKGLLPAHVKVAHKTGTWAFRFASDVGIITLPNNGHIAIAVYVKS +QAASDYSRSRAIALASRAIYDHf +>[subseq from] Class A beta-lactamase n=2 Tax=Elizabethkingia TaxID=308865 RepID=A0A5E8CZZ7_9FLAO +htSILNDINAVTKDKKATVAVSVLGIENEFQFsNTNGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKNVKALYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTRTNTGMAKLPGLLP-KVKMARKTGSSGKMAENDSGIITLANGKHYAIAVFVKD +SMESEEVNCGMIAQISKIVWDT- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI000937ED63 +--SLLKEINNITKGKKATVAVSVSGIEDNFQLsNNNGQLKMPMMSVFKFHIALAVLNQAD +KGNLTLDQKILVKKSDLHEWSPIREKYPQGNLPLSEIIYYTVAQSDNNGCDILLRLLGGT +QAVQKFVNSKGIKNIQIKHNEEEMHTKVQVLYENYTTTSSMVKTLKSFYKNMMISKKSTD +FLMDIMLKTDTGMAKLPGLLP-NVKMARKTGSSGTVAENDSGIVTLDNGKHFAIAVFVKN +STESEEINYSIIAQVSKAVFDY- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013A5396F +------------------------------------------------------------ +-------------------------------MTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLYSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Odoribacter sp. Z80 TaxID=2304575 RepID=UPI00137A2585 +--TLQNQIKTLIRTHRAKVGVAIR-FGDKETI-ICNDSTRYAMMSTFKFPLALAVLSKLD +KKQLPLETEIYVTPSDLHPYSPLRDTRPEGSISISELLRYTVTLSDNNACDILIHYLGSP +AAIQDYLTRTGISGITIVATENTMHQQ-ENPYLNHCRPSAMTELLEKFLSKTLLSAPYQN +FLEKLMLATSTGADKLKGLLPPGTPVGHKTGSSDRNGDNDVGFIRLPDGRYFTIAVFIMD +SAEDDKANALLIARIARSAYEHy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A1B1S661_KLEPN +-----------------------MDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVIEKHLADGMTVGELCSAAITMSDNSAANLLLITVRSP +ARLTAFLTQIGNNFTRLDRWKTKLNEAIPGNALHTTTPVSMTATLPKLLTCQRLISRSQR +PLLQCMVDDPVAGTLILSVLPAGWFISDKTGASKRAARGIVS------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium amiense TaxID=135719 RepID=A0A494VXK2_9SPHN +--KLLAEFARFAALSDGSVGIGVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRIFSLID +AGDLRIDDPLALDPALASEGIAWMFSRPGATLSVQRLLELMLTKSDNNATDVLVARAGGP +QAITAFVTKLGVRGLEVDSDTAHLLYDFAIDPRDTSTPTAMLDLLTAYESGKALSAGSTQ +RLFTIMGHCETGKARIPGMLPPGTAVAHKTGSMN-GIGNDVGIVQLPDGRRFAVAVFVMK +DSRGHTSRDRIIAEATRAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. 17J27-24 TaxID=2555898 RepID=A0A4Y8ZRE0_9SPHN +------------------------------------------------------------ +------------------------------GTTARALMDAMITRSDNRATDLLIGALGGP +ASVDQWLRGHGLTGIRVDRTIAQLLSARRRDVRDSSTPTAMLGLLRLLDSGTALTPQSRS +ILLDMMRRCRTGSNRIRGILPPGATVEHKTGTLS-GYTGDVGFLTTPTGRRIAVAFFARG +GE----NRPAVIATAARMIYDAf +>[subseq from] penicillin-binding protein n=1 Tax=Hassallia byssoidea TaxID=482630 RepID=UPI000585C388 +--SLKNAVQNLALASNLTPGVFLVDLNNGAYV-DVNAGASFPAASTIKVPILVAFFQDVD +AGKIRLDETLTMQQDMVAGGSGNMQKPVGTQFTALEVATKMITISDNTATNMLIAKLGGI +EALNQRFRSWGLTTTVIRNKLPDLEGT------NTTSPKELGNLLMMVNQSNLVSLQSRD +RLLDIMRRTEK-DTLLPSGLGVGATIAHKTGDIGT-MLADAGLVDMPTGKRYIAAVMIQR +PNND-ARAEKLISAISGIAYQQf +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Calothrix brevissima NIES-22 TaxID=1973478 RepID=A0A1Z4K0S2_9CYAN +---LKSAVQNLIANPNLTPGVMLVDLDTGSYV-DINSNASFPAASTIKIPILVAFFQDLD +AGKIRLDEMLTMEQQAIAGGSGNMQYKPAGTFNALEVVSKMITISDNTATNILIARLGGI +ESLNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVSMRSRD +RLLEIMRQTQK-DTLLPSGLGTGATIAHKTGDIGT-MLADAGLVDMPTGKRYIAAVMIQR +PNND-TRAEKLISAISRTAYQQf +>[subseq from] class A beta-lactamase n=2 Tax=Rikenellaceae TaxID=171550 RepID=UPI0009E7A2B1 +--QFESRLDEILSGHKAFVGVAVR-TPGGETI--ARNDTLLPMMSVFKFPVALAVLDRMQ +REGIPLTQPISITPDLLLPYSPMRDSLPAGGLTLGQLLRYMVSESDNIACDILLREAGGP +EAVEAYVRSLGIGGIRIAASEEEMHRGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA +LLQRLLCGTTTGANKLKAGLPAEIVIGHKTGSSDRTADNDAGYVLLPDGRRYCIAVFVTE +SEENDATNAAIAASASRAAYEYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A657C3X3_9SPHN +--KLLGEFERFATXSDGTVGIAVRDLQTGXTQ-AIXGDTLFPMASAYKVAVAGRIFALID +AGDVRLDDQLALDPALASEGIAWMFSRPGASLSVQRLLELMLQKSDNNATDVLVARAGGP +AAITHFVKGLGVDGLRVDSDTAHLLYAFATEIEDTSTPRAMLDLLTAYESGKALSADSTQ +RLFTIMAHCETGKGRIIGMLPPGTAVAHKTGSLN-GTGNDVGVVRLPDGRRFAVVAFVMK +DSKGHKSRDRIIAEAARAAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus invocatus TaxID=173959 RepID=A0A3M8C2I0_9BACL +---WQQVIDEVLQEAQGEFGVAVTHLESGETA-GHQADQLFQMASVFKIPIIVTLMRDVD +AGKFRLDQRVTLRYEERVPGSGVLQELDSGALTVKDLAMLMTIVSDNYATDMLINLV-GL +ENIEAHMRELGLRNIYLPQTTWQLLNGEPTTANNVASPADLNRLLTMVAKKEILSEASCD +LILDILRRQQY-NSRLPLLLPEGTKVAHKTGTVN-GVVNDAGIIYLPDGGSIAITVLSRN +VA-EKQAAERTIAQVARAVYDQ- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. CF01-10NS TaxID=2292956 RepID=A0A3A5S8W8_9BACE +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLETRLPIKKSDLKLYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP +DAVNKYIYSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD +FIFQTMVECQTGQDRLVALLNKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD +SEENNQANNKIIANISRIVYEY- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. CENA543 TaxID=1869241 RepID=A0A2I8AD04_9NOSO +--TLKNAVQELAAANNLTPAVFLADLDTGGYV-DLNADNSLPAASTIKVPILIAFFQDVD +AGKIRLDEMLTIQQEMIVGGSGDFQYKPAGTYPALEVATKMITVSDNTATNMLIARLGGI +EAVNQRFQSWGLTSTVIRNPLPDLSGT------NTTSPKELGNLLAMVSQGKLVTMRSRD +QILDIMRRTQR-DQLLPAGLDAGARAYHKTGDIGT-LLADAGIIDTPTGKRYIAVVMVQR +PNND-PRAEKLISSISRAAYQEf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=A0A0P0EXG0_BACT4 +--SLENQLKQAIQGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DAVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGRAYSIAVFVKD +SEENNQENSKIIADISRIVYEY- +>[subseq from] serine hydrolase n=1 Tax=Novosphingobium rosa TaxID=76978 RepID=UPI000A06F348 +---FEARLASVANAAHGRIGVAAVDLSNGKGI-SVMGDQPFPMASTVKVAIVATFLDGVD +QGKFRLTDRFPIMMPLPSRGSGPAPQREGPIYSATQLIDMTIIHSNNHATDAILAAIGGP +KAVDRWLHKAGIGGMRIDRDIATLVRATTIDLRDSTTPQAMATLLAGLYQGQWLTPGSRA +VLLSAMSRCATGTHRMRGLLPNDAIVGHKTGTLNN-TASDVGIIRTADGRNIAIAIYVTG +QG-SKPGRDSRIASIARTVYEGy +>[subseq from] Serine hydrolase n=1 Tax=Westiellopsis prolifica IICB1 TaxID=1970206 RepID=A0A4V2JNA0_9CYAN +--SLKTTVQSLASANNLTPGVFVVDLENGSYV-DINASASFPSASTIKIPILVAFFQDVD +TGKIRLDEMLTMEKEMMVGGSGDMRYKPAGTFKALEVANKMMTISDNTATNMLIARMGGI +EALNQRFRNWGLNTTVIRNQLPDLDGT------NTTSPKELGNLMAMVSQGNLLNMTSRD +RILGIMRNTVR-NQLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVAVMVKR +PNND-PSAEKLIGSISKAAYQQf +>[subseq from] serine hydrolase n=1 Tax=Calothrix sp. PCC 7507 TaxID=99598 RepID=UPI0005A63967 +--------QTLAAANHLMPGIFLVDLDTGSYV-DINGAASFPAASTIKIPILVAFFQDVD +AGKIRLDEMLTMQQEAIAGGSGNMQKPVGTQYTALEVATKMITISDNTATNMLISKLGGM +EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPRELAQLMAIVNQGTLVNMRSRD +RLLDIMRQTQR-DNLLPSGLGAGASIAHKTGDIGT-MLADTGLVDIPTGKRYIASVMVQR +PNND-PRAEKLISAISQATYQQf +>[subseq from] Serine hydrolase n=1 Tax=Mastigocladus laminosus UU774 TaxID=1594576 RepID=A0A4D9CKW3_MASLA +--SLKTTVQSLASANNLTPGVFVVDLENGSYV-DINASGSFPSASTIKIPILVAFFQDVD +AGKIRLDEMLTMEKEMMVGGSGDMRYKPAGTFKALEVANKMMTISDNTATNMLIARMGGI +EALNQRFRNWGLNTTVIRNQLPDLDGT------NTTSPKELGNLMAMVSQGNLLNMTSRD +RILGIMRNTVR-NQLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVAVMVKR +PNND-PSAEKLIGSISKAAYQQf +>[subseq from] Beta-lactamase n=1 Tax=Calothrix sp. PCC 7507 TaxID=99598 RepID=K9PH05_9CYAN +--------QTLAAANHLMPGIFLVDLDTGSYV-DINGAASFPAASTIKIPILVAFFQDVD +AGKIRLDEMLTMQQEAIAGGSGNMQKPVGTQYTALEVATKMITISDNTATNMLISKLGGM +EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPRELAQLMAIVNQGTLVNMRSRD +RLLDIMRQTQR-DNLLPSGLGAGASIAHKTGDIGT-MLADTGLVDIPTGKRYIASVMVQR +PNND-PRAEKLISAISQATYQQf +>[subseq from] Beta-lactamase class A n=1 Tax=Hephaestia caeni TaxID=645617 RepID=A0A397P9T2_9SPHN +---LVAAIKAIGTQFDGKVGIAVQSINQGWTV-SSNGDVKMPQQSVSKLWVALTVLDLRD +QGRLTLDDPVTVTKADLTLHQPVASLVGDTGTTVRDLQYRAITSSDNTANDRLLSYVGGP +EAVRAMIARKQLGAIRFGPGERLLQSAYVADPIDGASANAIADALARLVKGDLLSPSSTQ +WLIQTMSETRTGRARLRANLPGGWSIAHKTGTGQTAGFNDVGVLTAPDGRRYTVAVLIGD +TSRPVRERQQLIQSVAGAVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium taihuense TaxID=260085 RepID=A0A562JS65_9SPHN +--AIQQQVAAIAAEGRGRIGVAAMDLDGGGQI-FVNADMPFPMASTAKVAVAATFLEQVE +KGTFRLDQQFPMMIPVRETGARSAEAPLRSGMTAQSLMELMITRSHNEATDGLIRAVGGY +ENVNRWLSAKGIVGQRLDHTMATLVRARVIDVKTSSTPRAMLALLSAIDRGGALSPESRA +VLLDTMTRTTTGKNRMRAGLPEGTLVAHKTGTLA-GVTDDVGIVRLPDGRHLAVVFFVTG +PEG-HTVHAGLIARMMRTIYDGy +>[subseq from] CME-1 protein n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=Q9RAZ9_ELIME +htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter litoralis TaxID=39960 RepID=A0A074MVK9_9SPHN +---FEQRIAALADGSNGRIGVAAVDLATGDQI-AVLGDQLFPMASTSKIAIAATYLDMVE +KGQFSLTSEWPLMIPIRSASSPAAPVREGKYMQAIDLIEIMITRSSNPATDALLAAVGGP +ESVNEWIRRQGINEFSINRDIATLVRASYIDPRDAATPKAMVRLLTGLYRGDFLSDTHRR +VLLGAMSRTVTGKRRIVANMPDEAVVSHKTGSLNN-TSSDIGIIEYPDGRAIAVAIYVTG +QG-SRLAREQRIAAIARALYDGf +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter luteolus TaxID=295089 RepID=UPI00136B09E6 +--SFERQLAKVADGDQGRIGVSAIDLTTGYQV-SVLGDQRFPMASTSKVAIAATFLAGVD +QGRWSLTSEFPLLIPVKSGSSPRAPVREGTYLPAEQLLNLMISKSSNASTDALLRVVGGP +QAVNAWMRRAGIDDFELSRDIATLVRATRIDNRDSATPNAMAKLLAGLYQGKWLSRSSRD +VLIGAMENTTTGKRRIRSALPMSANVAHKTGTLNR-MASDIGIFETPDGRAIAIAIYVTG +QSEARRKRDERIANIARALYNGf +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI0004132182 +htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] Beta-lactamase n=1 Tax=Fluoribacter gormanii TaxID=464 RepID=A0A377GMK8_9GAMM +--ELIKKLQAIEKNSNTVMGLTAIYIEKNKII-EHNSSQRFFMASTIKLPIAMAFLHRVD +EKKDSLDRVIKMDSSNSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP +KYVAKRMSALGFKNTFINRSIMEMFLRFQKDIRDTTTPDDMAKLLVKLYKKQALSESSTD +LLMKIMEQCRTGRSRIKGLLPPNVKVAHKTGTWSYRFVSDVGIITLPNKGHIAIAVYVKS +KSASDYPRSRAIALASRAIYDHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. 65-8 TaxID=1895852 RepID=A0A1Q3UNU6_9SPHN +---LSDRISQLWRTFPGKTGIAVQRIDGEWSF-SERGGELFPQQSVSKLWVAMTVLDAVD +QGKLSLDRQVDIGPNDLTLHQPLAARVRSEGMSVRDLIETAITHSDNTANDSLLRTVGGP +EAVRRFIAKKDLGSIRFGPGERLLQSAYLANPMDGAAPAAIASALTRLARGALLSPESTQ +YLMGVMSRTHSGPKRLKAGLPSGWDFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGD +TSASIPARMALMQAVSGAVAE-- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WGU3_9BACT +--ELSARLQKLCDRAGASIGLALMHVETGRTV-EIQGKTSLPLYSVFKLPLAIAVLKDVE +ENRLRLDQKVRVTPADVAPGSQGNAALWRKPKTVAELLELSIGRSDNTSSDKLLQLVGGP +DKVMQRMRSLGFQDIEIRSAVRELATR--QGKPNTGTASDLARLLSGLQQGQVLQPPQRT +LLLGFMERATTGLRRLRGDLPAGTIVADKTGTGEDGVTNDVGLITLPEGGHLAMAVLISG +SKLPAEAQEKLIAELAKTAYD-- +>[subseq from] Serine hydrolase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A0W1II93_9SPHN +---LSDRISQLWRTFPGKTGIAVQRIDGEWSF-SERGGELFPQQSVSKLWVAMTVLDAVD +QGKLSLDRQVDIGPNDLTLHQPLAARVRSEGMSVRDLIETAITHSDNTANDSLLRTVGGP +EAVRRFIAKKDLGSIRFGPGERLLQSAYLANPMDGAAPAAIASALTRLARGALLSPESTQ +YLMGVMSRTHSGPKRLKAGLPSGWDFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGD +TSASIPARMALMQAVSGAVAE-- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium CCH3-A5 TaxID=1768796 RepID=UPI0009E73F1B +-aKLDREIAGIERDSKGRLGVALIDLKDRTAW-SHRGSEHFPLQSVFKLPLAVAVLQAVE +AGTLRLDQPVTVTRKDLSLHSPLATRFKGERVPLRELVRLAAAESDNTAADLLTRLIGGP +QILTAMLKAGGVVGISVDRYERVFQPATLSDRRDAATPDASVAFLEAFAKGNWLRQPEHS +RLIEFAAGALTGKDRIRAGLPEGSRFAHKTGLGPNHATNDIGIVTLPNGRIFAIAVYLAG +STGAPEQREAAHAAVARLAVA-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI000332C3F5 +--SLLKEINNITKGKKATVAVSVSGIEDNFQLsNNNGQLKMPMMSVFKFHIALAVLNQAD +KGNLTLDQKILVKKSDLHEWSPIREKYPQGNLPLSEIIYYTVAQSDNNGCDILLRLLGGT +QAVQKFVNSKGIKNIQIKHNEEEMHTKVQVLYENYTTTSSMVKTLKSFYKNMMISKKSTD +FLMDIMLKTDTGMAKLPGLLP-NVKMARKTGSSGTVAENDSGIVTLDNGKHFAIAVFVKN +STESEEINYSIIAQVSKAVFDY- +>[subseq from] CME_2 extended spectrum beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=Q9RAZ8_ELIME +htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGIIAQVSKIVWDA- +>[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=A0A1T3D5V5_9FLAO +---LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQKFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNSAALLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] Uncharacterized protein n=1 Tax=Moorea producens JHB TaxID=1454205 RepID=A0A1D9G401_9CYAN +---LQKQIQTLVKQHQLQPGIFIHDLDTGAFL-ESNSRLIFPAASTIKLPILIAFFQDVD +AGKVFLDEYITMKPEMIAGGSGNMQQKPGKQYKALEVATKMITISDNTATNMLIERLGGI +EVLNQRFRSWGLKKTVLRNPLPDLPGT------NTTSPRELASLIFNLEQGKWISPQSRT +DLIDIMIQTKT-NTLLPQGLGNGATIAHKTGTLGR-LLADVGLVKMPNGKRYIISVMVKR +PFND-ASAEKLIRTISRQVYDYf +>[subseq from] Beta-lactamase n=1 Tax=Nostoc commune NIES-4072 TaxID=2005467 RepID=A0A2R5FGJ0_NOSCO +--SLKSAVQNLAATNNLTPGVFLLDLDTGNYV-DINASTSFPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMQQDMVAGGSGTLQRQPAGTYAALEVATKMITVSDNTATNMLIARLGGI +DALNQRFRTWGLTTTTIRNQLPDLQGT------NTTTPRELGNLMAIVSQGNLVSMPSRD +LMLDILRRTQR-DTLLPSGLGTGARVYHKTGDIGT-MLADAGLIIVPTGKRYIASVMVQR +PNND-PRAEKLISSISSVSYQEf +>[subseq from] serine hydrolase n=1 Tax=Fortiea contorta TaxID=1892405 RepID=UPI000475D12D +----KNTVQTLAAANNLTPGVFLVDLETGAYV-DVNGAASFPAASTIKVPILVAFFQDLD +AGKIRLDEMLTMQQEAIAGGSGNMQKPPGTQYTALEVATKMITISDNTATNMLITRLGGI +EALNQRFRSWGLTNTVIRNQLPDLQGT------NTTSPRELSQLLAIVNQGNLVNMRSRD +RLLDIMRQTQR-DNLLPSGLGTGASIAHKTGDIGT-MLADTGLVDIPTGKRYIATVMVQR +PNND-PSAEKFITSISRTAYQQf +>[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. M24A2M TaxID=2682494 RepID=UPI0012EBB6A2 +--AFEARIASLANASQGRIGVAAMDLKTGKVV-DVLGDQRFPMASTSKIAIAATFMEGVE +QGRWSLTSEFPMMMPVRSESTAVAPVRAGEYYSAERLIELMLTRSNNYATDALLRVVGGP +RAVNEWTRRAGITDWQIDRDIATLVRAEVIDTRDSATPLAMVQLLAGLHEGKWLSDRSRA +VILGAMGRCVTGKRRIVANLPSEARVAHKTGSLFN-TSSDVGIIQTPDGRSFAVAIYVTG +QG-TRLNREARIASIARALYDGy +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter gangjinensis TaxID=1028742 RepID=UPI00136A3D9A +---FERRIAQIADGDEGRIGVAAVDLSTGQAI-SILGDQRFPMASTSKLAIAATFLEGVE +RGRWSLSSEFPLLVPVRSAYSSLKAPVRKGNLPASDLIEIMITRSSNSATDALLNVVGGP +SAVNAWMRRNGMDEFQLTRDIATLVRVAHIDERDSATPKVMVQFLTGLYQGRFLSASSRS +VIIGAMERCRTGKRRIPALLPDSANVAHKTGSLNN-TSSDIGTFITPDGRTIAVAIYVTG +QGAR-LKREARIAQIAKALYDGy +>[subseq from] Penicillin-binding protein n=1 Tax=Tolypothrix campylonemoides VB511288 TaxID=1245935 RepID=A0A0C2LVN1_9CYAN +---LKTVIQNLAAANNLTPGVFLVDLDNGGYV-DVNGSSSFSAASTIKIPILVAFFQDVD +AGNIRLDETLTMQKEMMVGGSGMRYKPVGTQFTAMEVATKMMTVSDNTATNMLIARLGGM +EVLNQRFQSWGLTTTAIRSPLPDLQGT------NTTSPKELGNLMAMVSKGNLVSMSSRD +RILDIMRRTVR-NHLLPTGLGPGATIAHKTGDIGT-TLADAGVVDMPTSKRYIVAVMVQR +PNND-ARAEKLIGSISRAAYQQf +>[subseq from] class A beta-lactamase n=1 Tax=Legionella drancourtii TaxID=168933 RepID=UPI00058BE755 +--ELAKKIAAIEKKSNTIMGVTAIYIEQDKVV-THNSTQRFFMASTIKLPIALAFLHRVD +EKKDSLTRVIKLDAKNSVPGSGSLYHLFEKKMSLQQILKYMLINSDNSASDTILQAANGP +KSVAKRMGALGFKNISINRSILEILLRFENDMRDTTTPEDMAKLLVKVYKKEALSEASTD +LLLNIMAGCRTGRSRIKGLLPAHVKVAHKTGTWAFRFASDVGIITLPNNGHIAIAVYVKS +QAASDYSRSRAIALASRAIYDHf +>[subseq from] Uncharacterized protein n=2 Tax=Dysgonomonas gadei TaxID=156974 RepID=F5J1N6_9BACT +---LRNDIEKIIRGKRATVGVALI-VDGKDTL-TVNNGFHYPTQSTYKFHLALAVLDYLN +KNNLSLDHKIFIRKAELLPHSPLRDDYPDGNLPVSEILKYTVSQSDNNGCDILFRFVGGT +SAVDRYIRDLGFSDFAIAATEEEMHGPWEVQYTNWSTPLTAARVLEKFRTGNILPQHFHD +FLWNAMVDTTTGPKKIKGLLPPGTIVAHKTGSSFNAAENDIAIIRLPDGRYYSLAVFVAD +SMEDEATNMRMIAEISRAVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc calcicola FACHB-389 TaxID=1357508 RepID=A0A1U7HIF1_9NOSO +----KNAVQDLATSNNLTPGVFLVDLDTGNYV-DINASTSFPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMQQDVMAGGSGNLQYKPAGTYAALEVATKMITISDNTATNMLITRLGGI +DALNQRFRSWGLTTTVIRNQLPDLEGT------NTTSPKELGNLMAIVSQGNLVSMPSRD +LMLDILRRTQR-DSLLPSGLGTGARVYHKTGDIGT-MLADAGLIIVPTGKRYVAAVMVQR +PNND-PRAEKLISSISRAAYQEf +>[subseq from] serine hydrolase n=1 Tax=Fischerella muscicola TaxID=92938 RepID=UPI0002DAAFB2 +--------QSLASANNLTPGVFVVDLENGSYV-DINASASFPSASTIKIPILVAFFQDVD +AGKIRLDEMLTMEKEMMVGGSGDMRNKPAGTFKALEVANKMMTISDNTATNMLIARMGGI +EALNQRFRNWGLNTTVIRNQLPDLDGT------NTTSPKELGNLMAMVSQGNLLNMTSRD +RILEIMRNTVR-NQLLPTGLGQGATIAHKTGDIGS-MLADAGLVDLPSGKRYIVAVMVKR +PNND-PSAEKFIGSISKAAYQQf +>[subseq from] class A beta-lactamase n=1 Tax=Fluoribacter gormanii TaxID=464 RepID=UPI0010411413 +--ELIKKLQAIEKNSNTVMGLTAIYIEKNKII-EHNSSQRFFMASTIKLPIAMAFLHRVD +EKKDSLDRVIKMDSSNSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP +KYVAKRMSALGFKNTFINRSIMEMFLRFQKDIRDTTTPDDMAKLLVKLYKKQALSESSTA +LLMKIMEQCRTGRSRIKGLLPPNVKVAHKTGTWSYRFVSDVGIITLPNKGHIAIAVYVKS +KSASDYPRSRAIALASRAIYDHf +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00136BFBAB +---LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQKFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNSAALLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDESEKIISDIGRATYDYy +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI000361857C +-nELKKRIENIITGKKADVGVSIIGGNKNDKV-QINGNQLYPMLSTFKFPIALTVLHKVE +KGELKMSQKIFIKKEELLDWSPFLEKYPQGNITLEDALMWMMCYSDNNLTDILIRLIGGT +DTVQKF---IGTKDFIIKNDEEDMHKAWDSQFINKITPNRATQLLDKFYQGKILNRVNTK +WLYEAMLNNKTGLKRLKGKLAADIKVAHRSGTSFTGAINSYGIIELPKNKKIVITVFVHD +TYENFNDSEAIIADIAKTVYDYy +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium chlorophenolicum L-1 TaxID=690566 RepID=F6EZS5_SPHCR +------------------------------------------------------------ +-----------------------------RLLPVRTLIDMSLTLSDNEATDALVARAGGP +QAVNDWVRAAGIKGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGKVLKPQTTA +LMLSIMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK +DHMGHELRDRIMAEAARAAYDYf +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia TaxID=308865 RepID=UPI000999C6D5 +htSILNDINAVTKDKKATVAVSVLGIENEFQFsNTNGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKNVKALYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMAKLPGLLP-KVKMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQISKIVWDT- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=A0A174SE91_BACT4 +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DAVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD +SEENNQENSKIIADISRIVYEY- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides finegoldii TaxID=338188 RepID=A0A642LXP6_9BACE +-sQLKTLLEQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIQYPLMSVFKFHQAVALADYMD +KKRLPLGTLLSIKKSDLKPYSPLRDQFPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DSVNRYIQSLGIRDCEITHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRRKTLFDEAYKN +FIYQTMVECQTGQDRLVALLGKGVTVGHKTGTGDFNGCNDIGFVLLPNGHAYSIAVFVKD +SAESSLKNSKIIADISRIVYKY- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000999E32C +htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGIIAQVSKIVWDA- +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. RIFCSPHIGHO2_01_FULL_65_24 TaxID=1802171 RepID=A0A1G3K0C1_9SPHN +---LDDRIFQIWKAFPGKTGIAVQRIDGEWAL-AQRGGELFPQQSVSKFWVTLTVLDAVD +NGRLSLDQKVRIGPEDLTVHQPIAARVQSEGLSVRELIEMAITHSDNTANDSLLRTVGGP +DAVRRFISKKDLGAIRFGPGERLLQAAYRASPPDGASPAAIAGALTRLARGTLLSPESTQ +YMLGVMSRTKSGPQRLKAGLPAGWTFLHKTGTGQTVGYNDIGIATAPDGTRYAIVVMMGE +ASSPIPARMATMQAVSRAVAE-- +>[subseq from] PenP, beta-lactamase class A n=1 Tax=Nostoc flagelliforme CCNUN1 TaxID=2038116 RepID=A0A2K8SLN2_9NOSO +--SLKSAVQNLVATNNLTPGVFLLDLDTGNYV-DVNASTSFPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMQQDMVAGGSGTLQRQPAGTYAALEVATKMITVSDNTATNMLIARLGGI +DALNQRFRTWGLTTTTIRNQLPDLQGT------NTTTPRELGNLMAIVSQGNLVSMTSRD +FMLDILRRTQR-DTLLPSGLGTGARVYHKTGDIGT-MLADAGLIIVPTGKRYIASVMVQR +PNND-PRAEKLISSISSVSYQEf +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI0004E3A5F7 +htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=UPI0009997E74 +---LKKTLESIISGKKATVGVSIMDPDTKEVT-WINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYNYy +>[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A127SLF7_9BACT +-qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI +DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD +FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQETDADNAAIIASISKIVYDT- +>[subseq from] Beta-lactamase n=3 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KKJ8_9BACT +-qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI +DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKHPLFGTQYKD +FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQENDADNAAIIASISKIVYDT- +>[subseq from] Beta-lactamase n=1 Tax=Parabacteroides sp. AF14-59 TaxID=2292240 RepID=A0A3R6PQN9_9BACT +-eQLKANIQEIIKDKKARIGVGII-LNGKDTV-TVNNEDRYPMMSVFKFHQALAVLNYLQ +QNNLPLDTQIRIEKEDIIEYSPLRDKYPQGNLPISELLKYTIQLSDNIACDVLFKYIGGP +SVADKYIRSLGLQQFSIVITEDDMHLDLSACYLNWSTPLEAARLLDILLTRSLFKEEYQE +FIKNIMIECETGKDRLPLLLKTKAVIGHKTGTSDKGGTNDIGFVLLPDGSRYTVAVFIKD +SNESMETNAKIIASISDVIYKY- +>[subseq from] Serine hydrolase n=1 Tax=Symploca sp. SIO1C4 TaxID=2607765 RepID=A0A6B3NLY9_9CYAN +--QLKAQMHAIVAQNNLQPGVFLLDLDTGAYL-DWDSRSTFAAASTIKVPILVAFFQALD +AGKVRLDETLIMESEMIATGSGDMQQQPGTQYTALEVITKMIAISDNTASNMIIARLGGA +EALNQQFRSWGLATTAIRNLLPDLEGT------NTTSPREIARLMSIVNQGQLLSLRSRD +RLLDIMRQTQN-DSLLPQGLGNGATIAHKTGNIGS-VLADVGIVDMPTGKRYLIAVMVKR +PH-DDASAQKLIRDISRTAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A4Q5R3N7_9PROT +------------------------------------------------------------ +--------------------------------SATQLLELMIVRSDNGATDLLLAALGGP +ATVQQWLWSQKITGMRVDRTIAQLLRGHLADSKDVATPVAMVALLNKLDSGDVLTPRSRT +FLFDLMRRCETGTRRIRALLPAGTMVEDKTGTLD-GVTNDVGFINMPDGRRVAIAVFARG +GR----DRQPVIAQVSRMIYDRf +>[subseq from] Uncharacterized protein n=2 Tax=Bacteroides caccae TaxID=47678 RepID=I9EQW5_9BACE +--SLETQLKEAIKDRKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA +KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNTCDILFDYQGGP +DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD +FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD +SEESFAENSKIIADISRIVYEY- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00084018A8 +--ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAILNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=A0A0W8ETH8_ELIMR +--ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNQVD +RGNLALDQKILVKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT +NTVQKLMNVNGVKNFQVKYNEEKMHKNVKALYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMTKLPGLLP-KVKMARKTGSSGTVAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQISKIVWDT- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6B2F408_KLEPN +------------------------------------------------------------ +-------------------------------------------DSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PEQKAESRRDILAAAAKIVTHGf +>[subseq from] Beta-lactamase TEM (Fragment) n=1 Tax=Escherichia fergusonii TaxID=564 RepID=A0A679G4T1_ESCFE +---------------GARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTCANI------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0N9HP03_9BACT +-aELEKQIAKIAESAKGKVGVAAVLLETGDSA-MLISDQRFPMQSVYKLPISMAVMDQTR +RGELDLDEKIGVTKEDMVGHSPLRDANPNGGFTIRELIRFALVESDGTASDVLMRIAGGG +PQIQNFLTQIGVKNMRVLNTEKDLALDWQKQYQNYSTPNDAIELLRWLQTSTLAEDKAND +ELVMWMEASIPGAKRFKGSLPPNTIVAHKTGTSGTAATNDIGIITLPNGKHIAIAVFVSD +SPADQDARETVIARVAKAVWDRw +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides clarus TaxID=626929 RepID=A0A1Y4JZ20_9BACE +-qTLESKIDDFLKGKKAMVGVAVM-TGRNKIL-LHNNKMNYPLLSVFKFHVALAVLDKMN +KQETPLDHIVHVKASQLQPYSPLRQKYPNQDISLGELLRYSISLSDNNACDILIEYAGGI +GHTHQYINKLGICDFNLSETEDSMHRNPSKTYLNWSTPAEMVRLLEIADKKELFDPIYKD +FLWNTMIATSTGSNKLKGLLPSNTIVGHKTGSSDRNADNDAGVVIMPDGKKYYIAVFVMN +SRETDDENAAIIARISRMVYDEy +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. AM10-21B TaxID=2292001 RepID=A0A415CLM8_9BACE +-qTLESKIDNFLKGKKATVGVAVL-TDRNEIL-LYNNKMNYPLLSVFKFHVALAVLDKMN +RQETPLDHIIHVKASQLQPYSPLRQKYPNQDISLGELLQYSISLSDNNACDILIKYAGGI +GHIHQYIKKLDINDFNLSETEDSMHRNPSKAYLNWSTPYEMVQLLRIADEKELFAPVYKD +FLWNTMIATSTGSNKLKGLLPSNAIVGHKTGSSDRNADNDAGVVIMPDGKKYYIAVFVMN +SSETDDENAAIIARISRMVYDE- +>[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=A0A1A6CGR1_ELIMR +---LKKTLESIISGKKATVGVSIMDPDTKEVT-WINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRATYDYy +>[subseq from] Class A beta-lactamase n=1 Tax=Novosphingobium sp. Fuku2-ISO-50 TaxID=1739114 RepID=A0A102DC07_9SPHN +--------GALERRSGGRLGVMVLDSARARGF-GWRQDERFAHCSTFKLSLAAMVLAQID +AGRARGDEVVPYSVLDVLPASPVTDPVLAGQLPVFALAEAAVERSDNLAANLLLARFGGP +AALTAFWRATGDPISRLDHHEPALNRVAPGADQDTTTPAAMAATVARLLTGSVLSGESRA +RLWGWMKGAPTGLGRLRGGLPARWQGGDKTGTWTPAKINDIALALAPVGAPLAVTAYYEP +LGAVRPEDEAVLAAVMRIAAD-- +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter mangrovi TaxID=1982042 RepID=UPI000BA24A29 +---LEQLVGQIADGSKGRIGVAAVDLATGEQV-SVLGDQRFPMASTSKIAIAATFMQGVE +DGRWTLTSEFPMMVPVRSESSAVAPVRPGRYYQAVDLIEMMITRSNNEAADALLKVVGGP +KAVNAWVHAHGVENFHIDRDIATLVRASHIETRDSATPKAMVKLLTDLYQGKVLSDSSRQ +VILGAMERCRTGVRRIKALLPDDAIVAHKTGSLHN-TSSDIGLVKAPNGHTIAVAIYVTG +QG-SRLARESKIAHIALTLYDGy +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter longus TaxID=1044 RepID=A0A074M8S0_ERYLO +--SFEQRIAELADGSDGRIGVAAWDLATGEQI-TVLGNQLFPMASTSKIAVAAKYLEMVE +QGQYSLTTEFPLLIPVRSASSAAAPVRKGNSMAAIDLIEIMITRSSNPATDALLAAVGGP +QAVNDWMRRQGISDFSLDRDIATLVRANWIDPRDAASPKAMVRLLAGLYRGEYLSDESRR +VLLGAMSRTVTGKRRIVADMPGEARVSHKTGSLNN-TSSDIGIIESPDGRAIAVAIYVTG +QG-SRGAREARIASIARALYDGf +>[subseq from] Beta-lactamase n=2 Tax=unclassified Novosphingobium TaxID=2644732 RepID=A0A5C7UFL3_9SPHN +-qAIQQQVAAIAAEGRGRIGVAAMDLDGGGQI-FVNADMPFPMASTAKIAVAATFLDLVE +KGAARLDQQFPMMMPVRETGARSAEAPLRSGMTAQSLMELSITRSHNEATDGLIQAVGGY +DKVNRWLTSKGITGQRLDHTMATLVRARVIDVRTSSTPRAMLALLAAIDRGDALSPESRA +VLLDTMTRTSTGKNRIRAGLPVGTLVAHKTGTLF-GVTDDVGIVRLPDGRHLAVVFFVTG +PEG-HTAHAGLIARMMRTIYDGy +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas jatrophae TaxID=1166337 RepID=UPI000B838CE1 +---FLNSIQALGSGFAGDVGIAIRDVDEGWTV-AFNADTPMPQQSVSKLWVAITVMDAVD +RGTLSLNETVTVRRSDLTVHQPIRALIGPDGTTLHEILEMAMTRSDNTANDVLLRRVGGP +AAIRRMLADKGIARVRFGPGEPRLQARYLADPEDGATASGIADGLALLAQGRLLSPMSTA +NLLGLMRRSKTGPLRLRSGLPAGWSLAHKTGTGQSTGYNDVGLVAAPNGHRYAVAVLIAS +TRQPIPARMRLMGNVMRALVR-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=Q2FC38_STAXY +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDXRXXXXXXXKAXNSAILLEXVP +--YNXLNKKIHINKDDXVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRXXXEXNYXXPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDK----------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=A0A174U7I0_BACT4 +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DAVNQYIHSLGVTDCAIVCTENEMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLDKKVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD +SAENNQENSKIIADISRIVYEY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SW99_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAASD +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2W6SSF3_9SPHN +--KLLGEFARFAALSDGTVGIGVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRIFALID +AGKLRIDDQLALDPALASEGIAWMFSRPGATLPVQRLLELMLTKSDNNATDVLVARGGGP +QAVTAFVTGLGIKGLEVDSDTAHLLYAFVIDPRDTSTPTAMLDLLTAYDSGRALSADSTQ +RLFAIMGHCETGKARIPGMLPPGTAVAHKTGSMN-GIGNDVGVVRLPDGRRFAIAVFVMK +DSRGHTSRDRIIAEATRAAYDYf +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium sp. C100 TaxID=1207055 RepID=W1RP35_9SPHN +--KLLAEFGRFAALSDGTVGIAVRDLQTGETQ-AINGDTLFPMASAYKVAVAGRIFALID +AGDVRLDDQLALDPALASEGIAWMFNRPGASLSVQRLLELMLQKSDNNATDVLVARAGGP +QAITHFVTGLGVAGLRVDSDTAHLLYSFATEPEDTSTPKAMLDLISAYESGRALSADSTQ +RLFTIMAHCETGKGRIVGMLPPGTAVAHKTGSLN-GTGNDVGVVRLPDGRRFAVVAFVMK +DSKGHKARDRIIAEAARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. OM08-17BH TaxID=2292285 RepID=A0A374USD6_9BACE +-qTLESKIDNFLKGKKATVGVAVL-TDRNEIL-LYNNKMNYPLLSVFKFHVALAVLDKMN +RQETPLDHIIHVKASQLQPYSPLRQKYPNQDISLGELLQYSISLSDNNACDILIKYAGGI +GHIHQYIKKLDINDFNLSETEDSMHRNPSKAYLNWSTPYEMVQLLRIADEKELFAPVYKD +FLWNTMIATSTGSNKLKGLLPSNAIVGHKTGSSDRNADNDAGVVITPDGKKYYIAVFVMN +SSETDDENAAIIARISRMVYDE- +>[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium cucumeris TaxID=1813611 RepID=UPI0007870B6B +--DLKKTIESIISNKKADVGVSIIDPYHKERI-QINGNKLYPMLSTVKFPIALTVLNKIE +KGELSLQQKLLIKKEELLEWSPFRKEYPDGNISLEEAIKWMVSYSDNNLTDILLRLIGGP +EPVQQFINS---KDFIIRNNEEDMHKDWESQFVNKITPNETTKLLEAFNNGKILNKKHTL +WLYNAMLNNTTGTKRLKGNLPQHVKTAHRTGTSFTGAVNDFGIIEISGKKKFYIAVFIHD +TYEKFGDAEAIIADISKAAYEYy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Chryseobacterium sp. PMSZPI TaxID=1033900 RepID=A0A2N0XI14_9FLAO +-----------------------------------NGDKPLPMLSVFKFHLASTVLDLVD +KGKYSIDQKFLIKKSDLLEWSPLREKYPNGNLPLAEIISYTVAQSDNNTCDFLLKLIGGP +QTVQQFMDSKGVKNVHIKYNEDDMHRDWKTQYGNSSSTNSIVDLLKKFYDGKLISQKSTD +LLMQIMLGTTTGTNKIVEQLPKGTPIAHKTGSSGTVAENDMGIISLPNGKHYAIAVFVSN +STETEKVNTRIVSDISKVVWDDf +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00099A82E1 +---LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQEFIDS---TSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Alphaproteobacteria bacterium HGW-Alphaproteobacteria-15 TaxID=2013661 RepID=A0A2N3DL78_9PROT +--SFEQRIAELANADQGRIGVAAIDLATGEEI-MVLGDQLFPLASTSKIAIGAAYLEMVE +QGRYSLTSEFPLMMAVRSASSPKAPVREGQYMPAIDLIEIMITRSSNPATDAMLAAIGGP +AVVNDWMRRQGINDFSINRDIATLVRANHIDPRDAATPRAMVRLLAGLYRGEFLSDQSRQ +VLLGAMSRTITGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGIIETPDGRAIAVAIYVTG +QG-TRLAREQRIAAIARALYDGf +>[subseq from] serine hydrolase n=1 Tax=Croceicoccus mobilis TaxID=1703339 RepID=UPI0009ED2E3C +--QFRQQLFAAAPQGSGRIGVAALDLTTGETV-SILGDEPFPMASTSKIAVAATFLAGVD +AGKYSLFHQYPLEVPVASKSSNVAPTKPGQMMSAQTLIERMITRSDNAATDALLKAVGGP +KAVTQWVHKTGLTGFRIDRDIATLVRSRHVDVRDSTPPDQMVKLIAGLHEGKWLSASSRG +LLLGAMTRTITGRTRIKAGLPSGTVFGHKTGTLNK-TASDVGFVEMPDGRIVVMAIYVTG +QGGP-AARSAKIAEITRTLYAGf +>[subseq from] Beta-lactamase n=2 Tax=root TaxID=1 RepID=R6KHZ9_9BACE +-qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI +DQVNEYVKSLGIKDCNLVATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKHPLFGTQYKD +FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQENDADNAAIIASISKIVYDT- +>[subseq from] Class A beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A537MKE2_9PROT +---LTARIRELGRAFEGRVGIAVRDVDTGWVA-DWQGDRFYPQQSVSKFWVALTALQRAD +AGDLDLDRRVTVTRNDLTLHQPIAQQVGANGTTLNDLMFRALTQSDNTCNDIVLRHAGGP +AAVREMLTRNRLDGIRFGPGERLLQSRYVEDPVDGATPNGITNGLARLQRGELLSAESTR +RLLTIMSQTHTGPNRLRGGLAAGWTISHKTGTGQQAGYNDIGILHAPDGHHYALAVMIGR +TSTPLPARMELMQDVVRAAIAY- +>[subseq from] Beta-lactamase n=1 Tax=Legionella brunensis TaxID=29422 RepID=A0A0W0SUJ5_9GAMM +--ELAKKINRIEEKLNTVMGITAIHIEKNKIV-AHNGHKRFFMASTIKLPIALAFLHRVD +EKKDSLNRVIKLDSNNSVPGSGALYHLFEKKMSLRQILIHMLSNSDNSASDTILQVVNGP +GYVTKRMYALGFKNILINRSILEILLHFQNDIRDTTTPDDMAKLLVKLYKREALSESNTK +VLMDIMEKCRTGRSRIKGLLPPGVKVAHKTGTWAYRFASDVGIITLPNNGHIAIAVYVKS +QAASDYGRSRAIALASRAIYDHf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI0008416FB6 +--SLLKEINNITKGKKATVAVSVLGIEDNFQLsNNNGQLKMPMMSVFKFHIALAILNQTD +KGNLTLDQKILVKKSDLLEWSPIREKYPQGNLPLSEIIYYTVAQSDNNGCDILLRLLGGT +QAVQKFVNSKGIKNIQIKYNEEEMHTKVQVLYENYTTTSSMVKTLKSFYKNMMISKKSTD +FLMDIMLKTDTGMAKLPGLLP-NVKMARKTGSSGTVAENDSGIVTLDNGKHFAIAVFVKN +STESEEINYSIIAQVSKAVFDY- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000999A900 +htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKVLVKKSDLLEWSPIREKYPDGNLPLSEVITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMSKKVQAPYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] Beta-lactamase class A n=1 Tax=Pleurocapsa sp. PCC 7327 TaxID=118163 RepID=K9T1R6_9CYAN +---LKAKLEALAAKYKLQPGVFFVDLDSGNYV-NVRGEQGFSAASTIKIPILIAFFQDVD +AGKARLDEMLTMKKELIGGGSGDLQQQPGKQFSALETARKMIVISDNTATNMIIERLGGI +KALNQRFQDWGLTSTAIHNSLPDLEGT------NTTSPRDLAHLLAMVNRGELVSLKSRD +RLLGIMQETQN-RNLLPQGLEKDATIAHKTGDIGS-VLGDAGIVDMPSGKRYIASILVKR +PHND-GNAKKLIQGISRTAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. MI1205 TaxID=407020 RepID=A0A126R543_9SPHN +---LLGEFARFATLSDGTVGIAVRDLHNGETL-QYNGDTLFPMASIYKVAVAGKILSLAD +AGTLRLDEKLP---------------RLGTPLSVTTLLDLMLTRSDNEATDTLVARAGGP +QAVHGWLKSIGIRGQRVDSNTAQLLAAFAADPRDTSTPRAMNDLLSAIHHGKALKGSSTA +MLLGIMSRCKTGKARLVGMLPPGTPIAHKTGTLN-GLGNDTGIITLPDGRRIAISVFVMK +DHRGHAARDRIMAEVARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=A0A0H5GRY1_YEREN +--SVDKQLAELERNANGRLGVAMINTGNGTKI-LYRAAQRFPFCSTFKFMLAAAVLDQSQ +SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLIKELGGL +AAVNQFARSIGDQMFRLDRWEPDLNTARPNDPRDTTTPAAMAASMNKMAERK-------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Legionella cherrii TaxID=28084 RepID=A0A0W0SAG3_9GAMM +--ELIKKLNAIEKNSNTVMGITAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD +EKKDSLNRVIKMDSRNSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP +KYVAQRMSALGLKNIFINRSIMEMFVRFEKDIRDTTTPYDMAKLLVKLYKKQALSESSTN +LLMNIMEQCRTGRSRIKGLLPSNVKVAHKTGTWSYRFVSDVGIITLPNNGHVAIAVYVKS +KSASDYPRSRAIALASRAIYDHf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Olivibacter jilunii TaxID=985016 RepID=UPI00102F4467 +---LRRQIKEIILTGNAEVGVSILGIEDNDTL-SVNGYKHYPMISVFKFQIALTVLNKVD +KGELSLNQKIFIKKDELLEWSPFREKYPEGNITLKESLQWMVSHSDNNICDILIRLVGGV +HAIDTFIAS---PNFVIKNNEEEMHRNWDTQYVNTITPNFSTQQLKQFYEGRILTKSSTE +FLYKTMVETVVGPNRIKGKLPANAEVAHRPGSSFTAAVNDVGIIQLPNGKHFAIAVFVYN +TTEKYKTAEDMIASIAKATWDYy +>[subseq from] Beta-lactamase n=1 Tax=Taibaiella sp. KBW10 TaxID=2153357 RepID=A0A3N6ZXF8_9BACT +---LRKKIEGIISNKKADIGISIINPGEHDSI-QVNGDRFYPMLSTVKFPIALTILHKVA +AGELSMTQKIFIKKAVLLKWSPFREKFPGGNISLEEAMQWMICYSDNNMTDMLLRLIGGP +DSVQHFINS---KQLIVKNNEEEMHKDWASQFVNEVTPNEATRLLMMFDKGAILNKENTQ +WLYNTMVKNTTGVKRLKGKLPENVKVAHRTGTSFTGAINDIGIIELPDGKKIYIAVFIHD +TYEKFDDGEAIIAAIAKEVYEY- +>[subseq from] Beta-lactamase class A n=1 Tax=Nostoc sp. (strain ATCC 29411 / PCC 7524) TaxID=28072 RepID=K9QTL3_NOSS7 +----KTAVQDLAAANNLTPGVFLVDLDTGGYV-DINGDSSLPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMQQEMIAGGSGNMRFKPAGTYAALEVAKNMMTISDNTATNMLIARLGGI +EAINQRFRSWGLTSTAIRNPLPDLSGT------NTTSPKELVNLLAMVSQGKLVSMRSRD +QILDIMRQTER-DHLLPSGLGTGARAYHKTGDIGT-LLADAGVIDTPTGKRYVAAVMVQR +PNND-PRAEKLISSISRAAYQQf +>[subseq from] serine hydrolase n=1 Tax=cyanobacterium PCC 7702 TaxID=1173021 RepID=UPI000381C301 +-----TAVQDLVANNNLTPGVFIVDLDNGGYV-DINASSSFPAASTIKIPILIAFFQDVD +SGKIRLDEPLTMQKTMVVGGSGDMQKPVGTKFTTLEVATKMITISDNTATNMLIARMGGI +DALNQRFRSWGLTTTTIRNQLPDLQGT------NTTSPKELGNLMAMVNQGNLVSMASRD +RILDIMRKTVR-NHLLPTGLGEGATIAHKTGDIGT-MLADVGLVDLPTNKRYVVAVMVKR +PNND-PRAEKLISSISGAAYR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Elizabethkingia sp. YR191 TaxID=2135666 RepID=A0A2T5RTV8_9FLAO +--ELLEKINSITKGKKATIAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNQVD +RGNLALDQKILVKKSDLLEWSPIREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGV +KTVQKLMDVNGVKNFQVKYNEEEMAKKVQAPYANYTTTASMVKTLKAFYIGMFLSKRSTA +FLMEIMTKTNTGMTKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLGSGKHYAIAVFVKN +SMETEEVNCGMIAQISKVVWDT- +>[subseq from] serine hydrolase n=1 Tax=Nostoc sp. (strain ATCC 29411 / PCC 7524) TaxID=28072 RepID=UPI00083AE95F +----KTAVQDLAAANNLTPGVFLVDLDTGGYV-DINGDSSLPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMQQEMIAGGSGNMRFKPAGTYAALEVAKNMMTISDNTATNMLIARLGGI +EAINQRFRSWGLTSTAIRNPLPDLSGT------NTTSPKELVNLLAMVSQGKLVSMRSRD +QILDIMRQTER-DHLLPSGLGTGARAYHKTGDIGT-LLADAGVIDTPTGKRYVAAVMVQR +PNND-PRAEKLISSISRAAYQQf +>[subseq from] Serine hydrolase n=1 Tax=Hapalosiphonaceae cyanobacterium JJU2 TaxID=2109628 RepID=A0A328IIJ4_9CYAN +--SLKTSVQSLASANNLTPGVFVVDLENGSYV-DINASASFPSASTIKIPILVAFFQDVD +AGKIRLDEMLTMEKEMMVGGSGDMRYKPAGTFKALEVANKMMTISDNTATNMLIARMGGI +EALNQRFRNWGLNTTVIRNQLPDLDGT------NTTSPKELGNLMAMVSQGNLLNMTSRD +RILGIMRNTVR-NQLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVAVMVKR +PNND-PSAEKLIGLISKAAYQQf +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides cellulosilyticus TaxID=246787 RepID=A0A108T9G3_9BACE +-qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI +DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD +FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQETDTDNAAIIASISKIVYDT- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides cellulosilyticus TaxID=246787 RepID=UPI0012316B5B +-qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI +DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD +FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQETDTDNAAIIASISKIVYDT- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI0007398EBC +--ELLEKINTITKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAILNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMAKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGMITLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=unclassified Bacteroides TaxID=2646097 RepID=A0A416WDN7_9BACE +-kELEKRLQETIANKKAQIGIAVIM-NGRDTL-VVNNDCRYPMMSVFKLHQALAVADDCH +RRGRSLDTPVYIRKDDLKPYSPLRDKYPDGNLSIKELLEYTLLLSDNNACDILFSQTGGT +ETADKYIRSLGIEQFSIKVTEDEMHKDMNTCYLNWSTPLETAKVIELLLNKELFGREYQH +FIKQTMISCQTGKDRLPLPLETNAVIGHKTGTGDRNGTNDVGFVYLPDGQRYTIAVFIKD +SEESAQATSQIIADISRVVYQY- +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Nodularia sp. NIES-3585 TaxID=1973477 RepID=A0A218Q7S2_9CYAN +------TVQNLAANSNLKLGVFFVDLDTGSYV-DVNSATSFPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMEKDMISGGSGNLQQKVGSQYTALEIATRMSTISDNTATNMLIARLGGM +EALNQRFQSWGLSATAIRNPLPDLAGT------NTTSPRELGNLMAMVNQGNLVSLRSRD +LILDIMRRTER-NHLLPSGLGTGARIHHKTGDIAT-MLGDVGLIDIPTGKRYIAAVMVQR +PNND-PEAEKLISAISRAAYQQf +>[subseq from] Beta-lactamase n=1 Tax=Blastomonas sp. CACIA14H2 TaxID=1419876 RepID=W9BVW3_9SPHN +--GLRDELQELWRTFPGKTGIAVRRIDGDWVV-GQRGGELFPQQSVSKLWVTMTVLEKVD +RGEVSLDQEVTITANDLTLHQPLAARVAREGATVRSLINEALTASDNSANDALLRTAGGP +GAVNDFLRRKGLSNIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQSSTR +LMLDTLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLAE +TTASIPQRMQLMQAVSRAV---- +>[subseq from] serine hydrolase n=1 Tax=unclassified Anabaena TaxID=2619674 RepID=UPI00082D3847 +---LKNAVQELAANANLRPGVFLVDLDTGGYV-DINGDNSLPAASTIKVPILIAFFQDVD +AGKIRLDEILTMQQDMIAGGSGNMQFKPAGTYAALEVAKKMITISDNTATNMLIARLGGI +DAINQRFRSWGLTNTAIRNLLPDLSGT------NTTSPKELVNLLTLVSQGKLVSMRSRD +QILDIMRQTER-DHLLPSGLGTGARVYHKTGDIGT-LLADAGLIDTPTGKRYIAAVMVQR +PNND-PRAEKLISSISRAAYQQ- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=A0A139JZ57_BACT4 +--SLEDQLKQAIKGKKAKIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD +SEENNQENSKIIADISRIVYEY- +>[subseq from] serine hydrolase n=1 Tax=Nodularia sp. NIES-3585 TaxID=1973477 RepID=UPI000B5C9633 +------TVQNLAANSNLKLGVFFVDLDTGSYV-DVNSATSFPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMEKDMISGGSGNLQQKVGSQYTALEIATRMSTISDNTATNMLIARLGGM +EALNQRFQSWGLSATAIRNPLPDLAGT------NTTSPRELGNLMAMVNQGNLVSLRSRD +LILDIMRRTER-NHLLPSGLGTGARIHHKTGDIAT-MLGDVGLIDIPTGKRYIAAVMVQR +PNND-PEAEKLISAISRAAYQQf +>[subseq from] class A beta-lactamase n=1 Tax=Alistipes sp. AL-1 TaxID=1499682 RepID=UPI0009DDA20C +--QFESRLDEIVSGHKAFVGVAIR-TPDGKTV--ARNDSLLPMMSVFKFPVALAVLDRMQ +REGTPLTQPISITPDLLLPYSPMRDSLPTGGLTLGQLLRYTVSESDNIACDILLREAGGP +EAVEAYVRSLGIGGIRIAASEEEMHRGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA +LLQRLLCEATTGTNKLKAGLPAGTVIGHKTGSSDRTADNDAGYVLLPDGRRYCIAVFVTE +SEENDAANAAIAAAVSRAAYEYf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides faecis TaxID=674529 RepID=A0A3E5G5F6_9BACE +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DAVNQYIHSLGVTDCAIVCTENEMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQKYKD +FIYQTMTECQTGQDRLVALLDKKVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD +SAENNQENSKIIADISRIVYEY- +>[subseq from] Serine hydrolase n=1 Tax=Elizabethkingia anophelis R26 TaxID=1246994 RepID=A0A290MRX3_9FLAO +---LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQGFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNSAALLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDESEKIISDIGRAAYDYy +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A3B9CUG3_9PLAN +-dDLKHQLMPLIQSHGGNVAVSVLNLKTGYRF-DYRSTEVMPTASLIKLPVMIEAYRQIS +SGDLSLDVEIVLKAEDKVPGSGILTKHFGDGLKLRDAIQLMIGYSDNTATNLVIDQI-GL +AATAKTMAEMGYPETKLHSRVYRGSERSRKYGLGSTTSSDIVSLLERLHKRDLVSPKFSD +VMLKHLRDCEA-TAQLPRLLPPNLVIAHKSGAVSN-ARCDAGIIYAPNGA-LAICTLTSQ +NESKDNAAELLNARIAKTVFEHf +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter vulgaris TaxID=291985 RepID=UPI000694067B +-kALEQELVELGENFDGVTGIAVTEADTMATM-AHDGDTPFPQQSVSKLWVAMTALDLVD +NGALDLEEPVTLRSEDLTVYQPTRNIVRSRGTDYGDLLDRAITQSDNTANDRLLRRVGGP +QAVEAFMRRNGIAGVQFGTDERTKQSAYLSDPMDGAKASAMAKALARLARGDLLSEESTD +LILSTMEETKSGPRRLKGGVPNGWTFGHKTGTGQQSGYNDVGILTAPDGSQYALVVFIGR +TRASYAARMEMMQEVTRSVVRY- +>[subseq from] Beta-lactamase n=1 Tax=Fluoribacter bozemanae TaxID=447 RepID=A0A0W0RS01_FLUBO +--ELIKKIKDIEKKSNTVMGITAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD +EKKDSLNRVIKMDSRYSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP +RYVAKRMNALGFKNIFINRSIMEMFIRFEKDIRDTTTPNDMAKLLVKLYKKQALSESSTE +LLMKIMEQCRTGRSRIKGLLPANVKVAHKTGTWSYRFVSDVGIITLPNKGHIAIAVYVKS +KSASDYPRSRAIALASRAIYDHf +>[subseq from] class A beta-lactamase n=1 Tax=Fluoribacter bozemanae TaxID=447 RepID=UPI00104103ED +--ELIKKIKDIEKKSNTVMGITAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD +EKKDSLNRVIKMDSRYSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP +RYVAKRMNALGFKNIFINRSIMEMFIRFEKDIRDTTTPNDMAKLLVKLYKKQALSESSTE +LLMKIMEQCRTGRSRIKGLLPANVKVAHKTGTWSYRFVSDVGIITLPNKGHIAIAVYVKS +KSASDYPRSRAIALASRAIYDHf +>[subseq from] class A beta-lactamase n=1 Tax=Candidatus Hamiltonella defensa TaxID=138072 RepID=UPI00031282EE +------------------------------------------------------------ +----------------------LTKQNLADGMTVAELCSAAITVSDNTAANLLLSTIGGP +KGLTSFLQKTGDQVTRLDRWETQLNQALPGDERDTTTPKIMAQTLHNLLTGKILSAKSRQ +QLQTWMVMNKVGGPLLRSVLPANWFIADKTGAGNHGSRGIIAALGADGKPSRIVVIYLTE +TQATMDELNKQIAEIGASLIKHw +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=UPI0006D537EB +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNETHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD +SEENNQENSKIIADISRIVYEY- +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI001371BBEA +--MLKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] class A beta-lactamase n=1 Tax=Blastomonas sp. AAP53 TaxID=1248760 RepID=UPI000308EED1 +--GLRDELAQLWRTFPGKTGIAVRRIDGDWVV-GQRGGELFPQQSVSKLWVTMAVLEKVD +RGELALDTEVTITRDDLTLHQPLAARVAREGATVRTLINEALTASDNSANDALLRTAGGP +AVVNDFLRRKGLSNIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQSSTQ +LMLDTLGRTRSGPQRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLGE +TTASIPARMQLMQAVSRAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonadaceae bacterium 3R27C6 TaxID=2502220 RepID=UPI0010F5C949 +---LNDRIYELWRAFPGKTGIAVQRIDGEWSL-SQRGGELFPQQSVSKLWVALTVLDAVD +QGRMTLDQRVRIGPEDLVVHQPLAARVRAEGMSVRDLIETAITHSDNLANDSLLRTVGGP +AAVRAFITKKDLGSIRFGPGERLLQANYLANPVDGASPAAIASALTRLARGTLLSPESTE +YLQGVMSRTRSGPRRLKAGLPPGWQFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGT +TTAGIPARMALMQSVSSAVAEY- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Sporanaerobacter sp. PP17-6a TaxID=1891289 RepID=A0A1G4FG15_9FIRM +---LENKIREFIKNQKGNVAVAIKDLKTGKEI-KINENLVFPSASTIKLSIMSELFNRVN +AGSLNLNDKVELTENMKTGGDGILKEELGHKFTLKEIMTLMIIISDNMATNILIDLL-GM +DNINKRIKDMGLKNTRLQRKMMDSQAA-KEGRENLTTANDLCLILELIYRGENINEECSR +MMLDILKRQQV-RGRLDLYLPEDVIIAHKTGDLDC-LEHDVGIVYLPHRE-YIICVLTNE +TE-TNKDGREIIGKVSKMVYDEf +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000665F26C +---LKKTLESIISGKRATVGISIMGPDTKDVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQKFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNSAALLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPTGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] Beta-lactamase class A n=1 Tax=Elizabethkingia sp. YR191 TaxID=2135666 RepID=A0A2T5RRU4_9FLAO +-sQLKKTLESIISGKKATVGISVMSPDEKEVT-GINADQMLPMLSTVKFPLALAVLHEVE +KGKLSMAQKLFIKKEELLDWSPFKEKYPAGNITLEEALKWTVSYSDNNLTDILIRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNSATLLLQEFSNGKILNKAHTQ +WLYNAMLNNVSGKKRLKGNLPTGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Coprobacter fastidiosus TaxID=1099853 RepID=UPI000240E6C3 +-rELKMRIASVLKEKRATVGVAVLY-GDNRLF-EVNRG-DYPMMSVCKFPLALAVLDYLH +KNNLSLDTEIFIRESDLLPYSPLRDRHPQGNMSIRELLSYTVSLSDNNACDILFGYIGGT +KVVDDYIKRLGISGMSVVATEAVMHESFEKQYCNTATPSSAVLLLDKFLKEDLFRDEYGN +YLRKIMIETSTGNDKIKAGLPERVVMGHKTGSSDRNGDNDLAFVQLPDGQRYCIAIFIRD +SKEDDKTNAAIIASVSKVVYDY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonadales bacterium 63-6 TaxID=1895846 RepID=A0A1M3I5Z2_9SPHN +---LEQYVAKLADGTNGRIGVAAVDLTTGEQV-SVLGSQRFPMASTSKIAIAATFLEGVD +KGRWKLDDKFPLMVPLPSQSTKVAPVKAGRMLPARELIDLMLVHSNNQATDGLLAVIGGP +RAVNEWIKRAGIDGFSLDRDIATLVRSLYIDPRDSATPLAMVRLLQGLHDGRWLSKESRE +LLMVTMANCKTGPNRIKGQMPTDVMVAHKTGSLYN-TSSDVGIITGPDGHSIAVAIYVTG +GGMNRGYRIDRIATIARALYDGf +>[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=A0A0W8ETH1_ELIMR +---LKKTLESIISGKKATVGVSIMDPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMHQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWIVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=4 Tax=Bacteroides TaxID=816 RepID=A0A679H3X1_BACT4 +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD +SEESNQENSKIIADISRIVYEY- +>[subseq from] Class A beta-lactamase n=1 Tax=Mesorhizobium sp. TaxID=1871066 RepID=A0A3S3KRN3_9RHIZ +--RLRLQFEALANAHPARVGICAQG-RVLPPI-CVNGEQRFSLRSAVKIVIAAAVMQAVD +EQRMALDDRITIRREDLSVIQPTADIVVEKGTTIGDLVRRAVVDNDNAAADVLIARLGGT +SAIQAFLHKAGLQDIRIDRTERELQTAYLRDPRDTATPRAMVAFLQRLATGTLVSAASTA +YLLGVMEDTVNIPDGLRPGIPSDWTIGHRTGTSPNGVTNDVGILTTPWGDRIAVAVFVAE +SRADESERAALIAAAARAITSAy +>[subseq from] Serine hydrolase n=1 Tax=Altererythrobacter marensis TaxID=543877 RepID=A0A2W5AST8_9SPHN +---LAQRVAMLAAGDQGRIGVAAIDLTSGQMI-SILGDQRFPMASTSKIAIAATFMEGVE +QGRWTLSSEFPLLIPVQSPSSARAPVRPGSYMTAYDLIDLMITRSSNPATDALLAAVGGP +AAVNDWARRNGITDFTLTRDIATLVRANRIDIRDSATPMAMAQLLAGLHQGRFLSARSRQ +VILDAMERCKTGTRRIPALLPLTARVQHKTGSLNN-TSSDIGIFRLADGRPIAVAIYVTG +QG-TRLNRERRIAEIARGIYDGy +>[subseq from] Serine hydrolase n=2 Tax=Hydrococcus TaxID=1616833 RepID=A0A1U7HAC6_9CYAN +---LKAKLEALAAKYKLQPGAFFVDLDSGDYV-NVRGEQGFSAASTIKIPILIAFFQDVD +AGKVRLDEMLTMKKELIGGGSGDLQQQPGKQFSALEIARKMIVISDNTATNMIIERLGGI +KALNQRFRDWGLNSTAIHNSLPDLEGT------NTTSPRDLAHLLAMVNRGELVSLKSRD +RLLGIMQETQN-RNLLPQGLEKDATIAHKTGDIGS-VLGDAGIVDMPSGKRYIASILVRR +PHND-GNAKKLIQGISRIAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. SG61-1L TaxID=1603897 RepID=A0A0P6X4B8_9SPHN +--ALEQYVAKLADGTNGRIGVAAIDLTTGEQV-SVLGSQRFPMASTSKIAIAATFLEGVD +KGRWSLDDKFPLMVPLASKSTKVAPVKPGRLLPARELIDLMLVHSNNQATDGLLAVIGGP +KVVSEWVKKAGIDGFSLDRDIATLVRSLYIDPRDSATPLAMTQLLKGLHEGKWLSKSSRD +LLIVTMENCKTGANRIKGQMPADVQVAHKTGSLYN-TSSDVGIITGPDGHSIAVAIYVTG +GGMDRNYRTGRIATIARAIYDGf +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI0003FE7221 +--ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKRMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWD-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas koreensis TaxID=93064 RepID=A0A1L6JFV0_9SPHN +---LQSSIHALARNFGGVVGVSVRSLDAGWQI-DANGTRRMPQQSVSKLWVAMTVLDARD +RGRLTLDDPVTLTRENLTVHQPIAALVVKNGTTVRELLLRAMQQSDNTANDRLLNLVGGP +EAVRAMIRDKGLGDIRFGPGERLLQAAYVADPIDGAAPAAIALALARLKAGEILSPSSTR +WLMTVMEASRTGKYRLRGAVPPGWSFGHKTGTGQTAGYNDVGILTAPDGKAYSIAVMIGD +TPRPIKERQELMQGVVAAVVAQ- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingorhabdus sp. Alg231-15 TaxID=1922222 RepID=UPI000D560857 +---LEREIADLWRSFPGKTGIAIKSIDNGWSI-GHREDQNFPQQSVSKLWVAMALLDKVD +QGRISLSDSIRIGPDDLTLYQPLAAEVKREGKSVFTLLEKSLAFSDNTANDALLRHAGGP +DAVNDFIRRSRLGKIKFGPGERLMQSAYLADPIDGASPGAIVNALDRLARGDLLSENSTR +LLQSILKRTRSGPKRLKAGVPAGWEFLHKTGTGQATGYNDVGIMTAPDGSRYAVAVMLGD +TTASVPERMRMMQSVTRAVARY- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000CE93CCF +htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGISKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Reichenbachiella versicolor TaxID=1821036 RepID=UPI000D6E4502 +---LKKEIQNTLKDKDATVGVSIIGPSSLDTL-SINGDLHLPMQSVYKFHLAAAVLHRVD +QGELNLSDTIEITKEQLDNWSVIRKDYPNGGLSLGQVIKYTVAVSDNVGCDLLFEMIGGP +SVAQEYMNKIGITDIAILHNEETMQSEWSIQYLNWTTAKSATKVLKTLYEDNLLSTASHQ +FLWDVMKSSWVGKLSMKTYLPETTVIAHKTGHSGTAAQNEIGIIWLPNGDYFYISILVSD +SSEESEVNRKLLADITKLTWDYf +>[subseq from] serine hydrolase n=1 Tax=Blastomonas sp. UPD001 TaxID=2217673 RepID=UPI000E350EB0 +--GLRDELQELWRTFPGKTGIAVRRIDGDWVV-GQRGGELFPQQSVSKLWVTMTVLEKVD +RGEVSLDQEVTITANDLTLHQPLAARVAREGATVRSLINEALTASDNSANDALLRTAGGP +GAVNDFLRRKGLANIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQSSTR +LMLDTLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLAE +TTASIPQRMQLMQAVSRAV---- +>[subseq from] Beta-lactamase n=1 Tax=Sutterellaceae bacterium TaxID=2026794 RepID=A0A3D3SEQ5_9BURK +--DLTSDIQEVIKGKKAQVGVAVLY--KDDAF-TANNDDQYPLMSVFKFHIGLAVLKKME +KEGIPLTAVVTLGPSDIDTWSPMYKKYKSKKLSYGDLINYMVSQSDNNACNWLINFVGGI +QNVNDFIKNLGIDRIQLIETEKSMEQDIRKSYNNWSTPLSVTQLLRKVYTEKVLSDEHFA +FLEKAMLASASGKDKFRAGLPKEVEVGHKTGMSYRTCDADVGVIYMPGGEKCYLAVLVKD +SKETDAANAKIMADIAKKVYSHy +>[subseq from] serine hydrolase n=1 Tax=Scytonema millei TaxID=1245922 RepID=UPI0005845436 +-------------NAKLFPGMFFIDPETGAYL-DWNGDTTFAAASTIKFPILVAFFQDVD +AGKIRLDEKLTLKKELVGGGAGFQYKPLGSQFTALETATQMIIVSDNTATNLLIERLGGI +AALNQRFRNWGLTVTELRNLLPDLEGT------NTTSPKELAQLMVAVQKGDLISVKSHD +RLLNIMRRTHT-ATLLPKGLGPGATIAHKTGDIGS-MVGDVGLVDLPSGKRYIAVAMVKR +PHN-NAQAKELIRQVSRAAYQEf +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. TaxID=1883446 RepID=A0A522KKB4_9GAMM +--TLQGRLEALARQAPGTLGITVFDLQSGKVW-RVNAQRAFPMMSVFKAPVAAAVLDRIE +HHALSMEQPVVIRRSDLESGA-IREHFKGDQFTVRQLLTEAVSKSDNTAVDALLKVMGGP +RIVTAFLHDHGIDGMRVDIGENGFRSAFLADPRNRSTPDAAANFLRKLWDGQLLPPSSTR +YLLDLMYAQTM-PNRLRRGLPMGARLADKCGTSYTAAYNDIGILSWPDGRAVVVAAFLTA +STASKDERDAIFADLARTVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Shigella flexneri TaxID=623 RepID=UPI0012E7416F +------------------------------------------------------------ +-------------------PSPLTSQHIADGMTVSELCNAAITTSDNTAANLLLSTIGGP +EGLTHFLRSTGDSYTRLDRHEPSLNEAKPGDERDTTTPAAMAQTLQKLLNESVLTEKSRK +KLISWMQEDKVGGPLFRSVLPAGWMIADKTGAGDHGSRGIVALLGPGGKPSRIVVLYITN +THSSMNELNEHIAGIGDSVIKNw +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas koreensis TaxID=93064 RepID=A0A2M8WDF0_9SPHN +---LQSSIHALARNFGGVVGVSVRSLDAGWQI-DANGTRRMPQQSVSKLWVAMTVLDARD +RGRLTLDDPVTLTRENLTVHQPIAALVVKNGTTVRELLLRAMQQSDNTANDRLLNLVGGP +EAVRAMIRDKGLGDIRFGPGERLLQAAYVADPIDGAAPAAIALALARLKAGEILSPSSTR +WLMTVMEASRTGKYRLRGAVPPGWSFGHKTGTGQTAGYNDVGILTAPDGKAYSIAVMIGD +TPRPIKERQELMQGVVAAVVAQ- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides clarus TaxID=626929 RepID=A0A412N1H3_9BACE +-qTLESKIDDFLKGKKAMVGVAVL-TDRNKIL-LHNNKMNYPLLSVFKFHVALAVLDKMN +KQGTPLDHIVHVKASQLQPYSPLRQKYPNQDISLGELLRYSISLSDNNACDILIEYAGGI +GHTHQYINKLGICDFNLSETEDSMHRNPSKTYLNWSTPAEMVRLLEIADKKELFDPIYKD +FLWNTMIATSTGSNKLKGLLPSNTIVGHKTGSSDRNADNDAGVVIMPDGKKYYIAVFVMN +SRETDDENAAIIARISRMVYDEy +>[subseq from] Uncharacterized protein n=2 Tax=Alistipes onderdonkii TaxID=328813 RepID=A0A1Y3QXI4_9BACT +--QFESRLDEIVSGHKAFVGVAIR-TPDGKTV--ARNDSLLPMMSVFKFPVALAVLDRMQ +REGTPLTQPISITPDLLLPYSPMRDSLPESGLTLGQLLRYTVSESDNIACDILLREAGGP +EAVEAYVRSLGIGGIRIAASEEEMHRGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA +LLQRLLCEATTGTNKLKAGLPAGTVIGHKTGSSDRTADNDAGYVLLPDGRRYCIAVFVTE +SEENDAANAAIAAAVSRAAYEYf +>[subseq from] Uncharacterized protein n=1 Tax=Streptomyces violaceusniger TaxID=68280 RepID=A0A4D4KXG4_STRVO +------------------------------------------------------------ +----------------------MTEKHVDTGMSLGALCDAAVRYSDNAAANLLFDQLGGP +KGLDAILEKLGDDVIQMENIEPELSRWVPGETHDTTTPRAMVKDLRAFVLGDVLGKGERA +QLTKWLRTNTTGDELIRAGMPKGWQVGDKTGSGSYGARNDIAVVWRPGAAPLVMAIMSYR +GDKDTPFDNKLIADAASVVAD-- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI0013662DA1 +htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANANLKMPMMSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPIREKYPDGNLPLSEIIAYTVAQSDNNGCDILLRLIGGV +KTVQKLMDVNGIKNFQVKYNEEEMSKKVQAPYANYNTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQVSKIVWDA- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. 1_1_14 TaxID=469585 RepID=D7I974_9BACE +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD +SEENNQENSKIIADISRIVYEY- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8G293_9BACT +-sKFEHRLQEIAARVDGVMGYAVLDVTSGDRF-GHLERDVFPTASTIKLAIVYELFKQVD +EGKLRLDQTITLDRKHAVGGSGVLVAMGTPTLSIRDYATLMVMLSDNTATNVLIDLT-GM +DNVTRRMAGLGLSATKLRRRMIDLAAAKRG-DENVSTPADIVRLLEALSKGEGLTSSSRD +EALALLKKPKA--SRLRKGLPPGIEAADKPGELE-GVRVDAGIVFAKNR-PYILCVMTTY +LK-DEAEGERAIEDASRAAYDYf +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T5B9_9BACT +--EVLQEFKSAENKSHGTVGAAAMDLQTGKRI-DINGDKPFPMQSVYKMPIAMAALGQVD +AGKFALDQKFTLKPEDYAQYSPIRDKNPDGGFSLLDLIRPTVSISDNSTSDYIMKLIGGP +GAVMTFLTDIGTSQIIVKNYEREIQSDWSLQYKNSSTPYAMVDLLGRLHLGEGLTSGSRE +TLLQIMRDTTTGPNRIKGKLPKSLIVAHKTGTSGAGATNDAGIITLPDG----------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000B35DCCD +---LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides faecis TaxID=674529 RepID=UPI000E5225BA +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKTYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DAVNQYIHSLGVTDCAIVCTENEMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLDKKVTIGHKTGTGDRNACNDIGFVLLPDRHAYSIAVFVKD +SAENNQENSKIIADISRIVYEY- +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Fischerella sp. NIES-4106 TaxID=2005456 RepID=A0A1Z4TQF6_9CYAN +--SLKTNVQSLASANNLTPGVFVVDLENGSYV-DINASASFPAASTIKVPILLAFFQDVD +AGKIRLDEMLTMEKEMMALGSGDMRYKPAGSFKALEVANKMITISDNTATNMLIARMGGI +EALNQRFRSWGLNTTVIRNQLPDLDGT------NTTSPKELGNLMAMVSQGNLISMTSRD +RILEIMRNTVR-NQLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVAVMVKR +PNND-PSAEKLIGSISKAAYQQf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides timonensis TaxID=1470345 RepID=UPI0004B08D60 +-qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KGHIALDSLIEVKSSQLTPYSPLRDEFPDQDISLGELLKYTISKSDNNTCDILIEYVGGI +DQVNEYVKSLGIKDCNLAATETLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD +FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQETDADNAAIIASISKIVYDT- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E7EMM5_9PLAN +-qSLEEKLKTIADSHKGVVAIAVKQLDTNESC-YLNADRVMPTASLIKLPIMIEAYRQAA +VEDLDLQKLISLRDEDKVPGSGVLTDHFSDKLPLIDCIQLMIAHSDNTATNLVLDEI-GL +PSTNRTMKRLGCPNTRVNAKVYRRDTSIAPEQSGSTTAREMVRLLEQLDQGQLVNKASCD +AMRRHLLTCQD-QTKIARLLPPGVSVAHKTGAVSR-SRTDAGLIEGPSGT-IAICVLTTD +NERDDNEANQLCGVLARAAYDHf +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas populi TaxID=2484750 RepID=A0A4Q6Y851_9SPHN +--ALARSINAVARSFDGRVGVAVRSIDKGWTI-ESNGDVRLPQQSVSKLWVAMTVLDFRD +SGRLTLDDPITLTRADLTLHQPVASLLKNGETTVGELLRRALTMSDNTCNDRLLRYVGGP +SAVRDFIARKGLGNIRFGPGERLLQSRYVADPPDGAAPRAIADALARLKKGELLSPMSTA +FLISTMESSKTGKQRMRGAVPPGWSFGHKTGTGQTAGYNDVGLLMAPDGRAYAIAVMIGD +TPRTIPQRQELMQSVVQAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Propionibacteriaceae bacterium NML 030167 TaxID=2016500 RepID=A0A255G9X6_9ACTN +----AALIADLERRHDVRIGLSAAALTRGRRL-DHRADERFLMLSVFKAIAAAAVLDGIT +PDPKVLDRPVFLPPEAICEGPAWFAEQIATRPSVAEVCRAAIQLSDSTAANALLSLTGGP +DSITRFARDNGDPVTQLTEWEPELNT--PDGDRNTTSPRAIGALFAAMIVGRALRTPARR +RLTDWMLGNQTSDQRFRAGLPAGWTLADKTGSGIDATANDVGIAFDPAGNAYQLAVLTSS +PRPDTERVNEIFAILAREAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=A0A174NCG0_BACT4 +--SLENQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNEIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLGKDVTIGHKTGTGDRNACNDIGFVLLPDGRAYSIAVFVKD +SEENNQENSKIIADISRIVYEY- +>[subseq from] Serine hydrolase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2W6SVI6_9SPHN +---LAQRVAMLAAGDQGRIGVAAIDLTSGQVI-SILGDQRFPMASTSKIAIAATFMEGVE +QGRWTLSSEFPLLIPVQSPSSARAPVRPGSYMTAYDLIDLMITRSSNPATDALLAAVGGP +AAVNDWARRNGITDFTLTRDIATLVRANRIDIRDSATPMAMAQLLAGLHQGRFLSARSRQ +VILDAMERCKTGTRRIPALLPLTARVQHKTGSLNN-TSSDIGIFRLADGRPIAVAIYVTG +QG-TRLNRERRIAEIARGIYDGy +>[subseq from] Uncharacterized protein n=1 Tax=Novosphingobium sp. SCN 63-17 TaxID=1660120 RepID=A0A1E4N3G1_9SPHN +---------DIERQYGGRLGFAVA-FSSGGIV-NWRGHERFAFCSSFKLSLAALVLTGAE +KGEWRLDEKLPFGKGEVLFNSPALQARLGLGISMAEAAEAVQKQSDNGAANLLMRRMGGF +DRVNRFWRGLGDMVSRLDDYETALNRVPPGSLRNTTTPEAMADNLFRMFRQGALSPAVVT +RLKDWMHDTTTGAKRLRAGLPGNWWAGDKTGTGLPGTYVDLAWVEPPDLAPFAIAAFYQP +PKPTDSNAETVLAQVGQNIAQ-- +>[subseq from] Beta-lactamase n=2 Tax=Altererythrobacter namhicola TaxID=645517 RepID=A0A1C7D4Y1_9SPHN +---VERNIAALADGSNGRIGVYALDLSTGMEV-SVLGDQRFPMASTSKIAIAATYLAGVD +QGRWTLQTEWPLLWPLRSKFSSARAPVKAGKMSAYELIDLMITRSSNPATDALLAAVGGP +QAVNDWARSVGMTEFTLTRDIATLVRAMHVDVRDSASPRTMGYLLAGIYNGHWLSASSRN +VILSAMERCITGKRRIPAQMPDYVTVGHKTGSLNN-TSSDIGFLTMPDGRTIVVAIYVTG +QG-SKRQREARIATIARGVLD-- +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00136E9996 +---LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLVGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] Class A beta-lactamase n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A2E3Y640_9BACT +---LEQELLRLGALSGGKMGIGVIHLETDQRL-YINNKERYPLASTYKVPIAVQLLKRVE +NGEITLNDMTDVQPKDQHPGSGILSDLVAPGLSLRNQLELMMIISDNSATDICLSAAGGS +KKIKRLLKKHKIRDMSIDRPTIGIIGKFEKDXRDTATPQAMAELLQMIWSNKILEKENSE +LLIDIMSRCQTGEGRLKGXLPKDTYVAHKTGTIG-ATTNDVGIIRLPNKGNVVVVAFVKD +SDLTIPERERAIAHVARSVHDYf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A523EA70_9BACT +--RLEHKIRTIADGVDGVVGVTIQDLTTAERF-ALRGDTVFTQASAIKLPVLVELFRQVE +QGRYGLDDIITLERDDIVPGSGVLQRLTPGSLTLRDVATLMVTVSDNTATNMIIDRV-GM +ENVNQTMARLGLPHTKLQRKMMDRE-AWLADRENLSTPNEQARLLELIHRGDVLSDASRK +ELLHILSIPKP--SRIRPLLPRGTRVAHKTGTVA-GVVVDVGIVYLEGR-PFIIAGMANW +LV-DGAEAERALEQIALAAYQYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=C3VJU5_STAAU +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPNSKKDTSTPAAFGTTLNKLIPNGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQA--------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium cucumeris TaxID=1813611 RepID=UPI000F45AE09 +--DLKKTIESILSNKKADVGVSIIDPYHKERI-QINGNKLYPMLSTVKFPIALTVLNKIE +KGELSLQQKLLIKKEELLEWSPFRKEYPDGNISLEEAIKWMVSYSDNNLTDILLRLIGGP +EPVQQFINS---KDFIIRNNEEDMHKDWESQFVNKITPNETTKLLEAFNNGKILNKKHTL +WLYNAMLNNTTGTKRLKGNLPQHVKTAHRTGTSFTGAVNDFGIIEISGKKKFYIAVFIHD +TYEKFGDAEAIIADISKAAYEYy +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E3D88AD +------------------------------------------------------------ +-----MNKEALIKKADLDEYAPVTSGIVGKKVSAADLCSITMRTSDNTAVNKVLEILGGP +QAVTAYLRKTGDNITRLDRNEPDLNEGTPGDVRDTTTPRAILETLNKLVLGPTLD--ERK +QLTTWLESNEVGDPLLRAGVPSDWRVADRTGAGGNGTRGVIAVMWPPKHAPIIAAIYITQ +TKATMEERNAAIASIGKAI---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A224A860_SHIFL +---------------------------------------------------------RSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGT----------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Rhodopirellula sp. JC645 TaxID=2605748 RepID=A0A5M6DIB1_9BACT +-eELAERVQPLVDKHAGDVAVVIKNLDGAGRF-QFRQDAPMATASLIKLPLMVTAYRRID +AGELEANRLLVLTEADKVPGSGILTDHFSGGLPLQDAIRLMIRYSDNTATNLVAEEV-GL +ARTAEMMASLGLQQTRMHSKVFRRDTSIDLDRSGSTTAAEMAALLERLYRDELASDASCQ +AMKAHLRACDD-GSKLAAGLPPGTPIAHKTGSVSS-VRTDAGIVQGPDGQAFLICVLTEN +NQTEDNAADKLISEIARAAYD-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. EP60837 TaxID=1855519 RepID=A0A173KVZ3_9SPHN +---LLGEFARFATLSDGTVGIAVRDLNNGETL-QLNGDTLFPMASTYKVAVAGKILSLAD +AGTLRFDEKLA---------------RLGTPLTVTMLLDLMLTRSDNEATDALVARAGGP +QAVNGWLQSIGIRGQRVDSNTAQLLAAFAADPRDTSTPRAMNDLLSAIQHGKALKGASTA +MLLGIMSRCKTGKARLVGMLPPGTPVAHKTGTLN-GLGNDTGIITLPDGRMIAISVFVMK +DHRGHAARDRIMAEVARAAYDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Apibacter sp. HY041 TaxID=2500547 RepID=UPI000FE3E720 +--PLEKTINSIIKNKKATVGVAVIY-DGKDTL-TVNNNYHYPTMSVFKFHQSLAVLDYMD +KNLLPLETPLFLKKSDLRPYSPLRDERPEGNISIGELVKYTVTKSDNNTSNALFHYMSGT +RMTDLYIRTLGIKDFAITATEAEMSEDFNNQYLNWTTPLAAARLLEVFLKDDLVSKDTRD +FLVNAMVQTTTGPDKLKALLPATTKIGHKTGSSARSADNDIGFVALPNGKQYSIAVFVMN +SMESDKTNARIIADISKAVYDFy +>[subseq from] CME-2 extended spectrum beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=A4GRC1_ELIME +htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD +SMEGEEVNCGIIAQVSKIVWDA- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI000D0EC894 +---WQQAVENVLKEAPGIYGIAAVHLETGETV-GHLDEELFQLASTFKIPIMVTLMREVE +AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELIGGI +DKVNEHMHELGLSQIHLRHNCWVLLNSIPTRDNNVATPAELNRLLIMIARKEILTEASCE +LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVND-VVNDAGIIYLPEGKGMIAITALSR +GVTDKEAAELTIARVAKAIYE-- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium HGW-Elusimicrobia-3 TaxID=2013765 RepID=A0A2N2EM74_9BACT +---LVEDLEKASRAYSGRVGIYIKDLETGKSW-EYNADRRFPSASLIKVPIMAAVFERIR +DGQLSLDTQIKLTRGLRVGGSGSLKWVREGTLSVMEIIYKMITESDNTATKMLIDSV-GM +DYLSGAFRGMNLEQTNITPEGMSLSSR-PVRRENYTTAREMGGLMERIYAGKLVDREASE +FMLDVLKHTKS-RTRLRRGLPLGWEIGHKTGLLRK-ACHDVGVVFSPRGD-FVIAVLTAE +VP-SYSSAKTFISRVAKLTYKYy +>[subseq from] Beta-lactamase n=4 Tax=Bacteroides TaxID=816 RepID=R6W5T9_9BACE +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DAVNQYIHSLGVTDCAIVCTENEMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLDKKVTIGHKTGTGDRNACNDIGFVLLPDGHVYSIAVFVKD +SAENNQENSKIIADISRIVYEY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A222U9G9_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPA--------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SUK8_9BACT +-----AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD +QGALNLEHIIHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQGRGNNTCDLLFALIGGT +ETVQKDLKEWGISGINVRFTEDEMLRNHDLQYANSSRPSAMNALLRAFDEGKILNKDTQR +LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD +SKDSAPACEKVIASMARWLCTEw +>[subseq from] class A beta-lactamase n=1 Tax=Litoreibacter sp. K6 TaxID=2601869 RepID=UPI00130A0CCC +--------EVIELSLLGDIGVYALDSENDRAS-GWSEDYRQPSNSTVKFLIATAVLYRVD +AGQERLDRGIHVDDMMPLSHSPVLENAHGDTMPVSAICAAMMTRSDNAAANLLLESLGGP +QSLTLWLRQMGDQVTRVDRYLPDLTTPPESPDSDSTTPAQMVRNMRTFLTGSAQLEGSRL +LLKNWMTENATGAHRLRAGVPQGWQVADRTGTGSDGRTSTIAAIYP-------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter sp. HL-46 TaxID=1479239 RepID=A0A0P8D4H8_9SPHN +--SFQQRIAELAEPSRGRIGVAAVDLATGEEI-MVLGDQLFPMASTSKIAIAATFLEMVE +QGRYSLTSEFPLLLAVRSAYSSAKAPVRKGQMPAIDLIEIMITRSSNPATDALLAAVGGP +EVVNDWVQRHGIHEFSINRDIATLVRARHIDTRDAATPRAMAQLLGGLYRGDYLSDESRR +VLLGAMSRTVTGKRRIVAHIPAEARVSHKTGSLNN-TSSDIGLIECPDGRTIAVAIYVTG +QG-TRLAREQKIAAIARALYDGf +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7W6X1_9BACT +------------QKSDAVIGVAAVDLQTGRRI-SVRDTERFPMGSVYKVPIAIEVLRTQQ +-----LERMITIEPKDFSPWSPLRDGADGKPMTIEDLAEWMVQASDNTACDALLRIV-TP +QAVTKRMRELGVRGIRIDRQEREMAARYATDPRDTTTPDAMLALFTAIAQHDGLSPANHA +KLMHWMTETTTGPHRIKAGIP-NAAIAHKTGTMP-GTVNDVAIIDN----RIVLAIFTKA +STTPDEKAEADIAAIARGVYDA- +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=UPI000999C068 +-tALKKTLESIISGKKATVGVSIMDPDKKGVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWVVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9DI69_9BACT +hsKLARQLEQTAAEFDGVMGLAVKDLTTGESF-AVNAAMVFPQASSIKITVLMELLRQAQ +AGKLKLDDRVAIKQVHMVGGSGVLQFFGDASISLRDLAVLMIVLSDNTATNILIDQV-GM +ANVNDTLAHLGLAQTRLQRRMIDTAAQ-RAGRENLSTPREMTTLLELLHGGKVLDASHTA +ALLEILKYPKENASPLRNGLPDGIALANKAGSLP-GVRCDSGIVLLPDR-PYVISVMTTY +GH-DSHAAERAISEVSRRVLEYf +>[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=A0A1T3IBW1_ELIME +--SLLKEINNITKGKKATVAVSVSGIEDNFQLsNNNGQLKMPMMSVFKFHIALAILNQAD +KGNLTLDQKILVKKSDLLEWSPIREKYPQGNLPLSEIIYYTVAQSDNNGCDILLRLLGGT +QAVQKFVNSKGIKNIQIKYNEEEMHTKVQVLYENYTTTSSMVKTLKSFYKNMMISKKSTD +FLMDIMLKTDTGMAKLPGLLP-NVKMARKTGSSGTVAENDSGIVTLNNGKHFAIAVFVKN +STESEEINYSIIAQVSKAVFDY- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia ursingii TaxID=1756150 RepID=UPI000751105C +--ELLEKINSITKGKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNQVD +RGNLALDQKILVKKSDLLEWSPIREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGV +KTVQKLMDVNGVKNFQVKYNEEEMSKKVQAPYANYNTTASMVKTLKAFYKGMFLSKRSTA +FLMEIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLGSGKHYAIAVFVKD +SMESEEVNCGMIAQISKVVWD-- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides intestinalis TaxID=329854 RepID=A0A415AJF8_9BACE +-qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSIFKFHVGLAVLDKMD +KGHIALDSLIEVKSSQLTPYSPLRDKFPDQNISLGELLKYTISKSDNNTCDILIEYVGGI +EQVNEYVKSLGIKDCNLAATETLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD +FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQETDADNAAIIASISQIVYDT- +>[subseq from] Class A beta-lactamase, subclass A2 n=3 Tax=Bacteria TaxID=2 RepID=A0A412P7V8_9BACE +-qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSIFKFHVGLAVLDKMD +KGHIALDSLIEVKSSQLTPYSPLRDKFPDQNISLGELLKYTISKSDNNTCDILIEYVGGI +EQVNEYVKSLGIKDCNLAATETLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD +FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQETDADNAAIIASISQIVYDT- +>[subseq from] Beta-lactamase n=3 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5L4Q5_9BACT +-----AAIREIVRPLKAKVGVSAVMLDTGESV-SVGDEAFYPMQSVYKFPLALSVLKRVD +QEVLNLDQKVHVTRDQLPEWSPLRDRFPQGGFPLKELLRFSVQESDNNACDILFSLIGGP +AAVQKDLKEWGVENMNVKYTEADTHRNHEWQYSNSARPSAVTFLFRMFDEGKILKKDTQL +FLWDMMASCATGAERLKGLLPKEYVVAHKTGTGGVSAINDAGIIVLPGGRRMAVTVFVMN +SKDSPAVCEGTIASVARWLCTEw +>[subseq from] Serine hydrolase n=1 Tax=Chroococcidiopsis cubana SAG 39.79 TaxID=388085 RepID=A0A433W660_9CYAN +------------NNTQLFPGMFFIDTETGTYL-NWNGDTTFAAASTIKFPILVAFFQDVD +AGKIRLDEKLTLKKELVGGGAGFQYKPLGSQFTALETATQMIIVSDNTATNLLIERLGGI +AALNQRFKNWGLTVTELRNLLPDLEGT------NTTSPKDLAQLMVAVQKGDLISVKSRD +RLLNIMRRTQT-ATLLPKGLGPGATIAHKTGDIGS-MVGDVGLVDLLSGKRYVAVAMVKR +PHN-NVQAKELIRQVSRAAYQEf +>[subseq from] Class A beta-lactamase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E9TZ04_9CHLR +-kSLKVELTRLADLSGGKMGIGVIHLESNQKV-YINNKDRYPLASTYKVPIAVQLLKRVE +KGEKSLEDLLDVQPEDQHPGSGIIGNFVTPGLSLRNQLELMLILSDNSATDICLTAAGGP +DQVKDILKKYNIQNMSIDRPTIGIIGKFGKDLRDTATPQAMAELLQKIWLNEILTREHSE +LLIDIMSRCQTGEGRLKGLLPPGTYVAHKTGTIG-ATTNDVGIIRLPNKGNVIVVAFVKD +SELEIPAREKAIAHVARAAHDFf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A2W6SKG7_SPHSX +---LQTKLDAEARSGSARVGLAAIDMTTGDMV-SVNGDQHFPMASTVKVAIAAAFLHGVQ +RGKLSLDATYRLPTDQRKMASGIGNMRAPQRLSGAQALDEMLTRSDNTSADILLAAIGGT +DALGRWLTTAGISGQRVDRSIAELLRAPVGDRRDSSTPEAMAALLAKLRNGELLDKERTL +YLFEVMARCRTGSGRIRGLLPAGTPVAHKTGTMN-GITDDVGIVGLPNGHELAVAIFETG +AG-GARAHDRKIAQLSRILYDHf +>[subseq from] Beta-lactamase class A n=2 Tax=Arboricoccus pini TaxID=1963835 RepID=A0A212RFB3_9PROT +------------------------------------------MCSTFKGLLGALILARVD +QGKESLQRRVTYSEQDLIFTSPITKTNVAKGMSVEDLLEAMLVYSDNTAAILLMRSAGGP +AALTQFLRGIGDTVTRSDRYEPKSNQY--DGALDTTSPRAIIGSAYQILIGNVLTPASRA +RLESGMIACKPGVRRIRASLPASWSIGDRPGENVTEESNDYAIVRPPGRAPLLIATYYDD +PHRSTADREAVIRDVGSAFV--- +>[subseq from] Class A beta-lactamase, subclass A2 n=3 Tax=Bacteroides TaxID=816 RepID=A0A3E5HJ85_BACT4 +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLNYTLQQSDNNACDILFQYQGGV +DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD +SEENNQENSKIIADISRIVYEY- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=2 Tax=Sphingomonas haloaromaticamans TaxID=653954 RepID=A0A1S1HEN3_9SPHN +---LEARIATLGQSFSGSVGIAVRDVSTGWAV-SYNAQRPMPQQSVSKLWVSMAVLDAVD +RGTISLSEPVTVRRDNLTVHQPVRAMMGANGTTYGALMRIALTQSDNTCNDMLLRRVGGP +DAVRGMILRKGLGRIAFGPGETLLQSRYLADPMDGATAEAIAGALARLKRGELLSPASTR +LLLTTMGDSRTGPQRLRAGLAPGWTLAHKTGTGQATGYNDVGVITAPDGRSYAVAVMIAS +TRQPIPVRQRLMADVVRAVVA-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides faecis TaxID=674529 RepID=UPI00110758AA +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DAVNQYIHSLGVTDCAIVCTENEMHQDESLCYQNWTTPLAATRLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLDKKVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD +SAENNQENSKIIADISRIVYEY- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingosinithalassobacter sp. zrk23 TaxID=2711215 RepID=UPI0013E171B8 +------VITDLERRFDGVVGIAVNSVDDGWKI-AANGDRRLPQQSVSKLWVAMTVLDYRD +QGRLSLDDPYTVTKADLTVHQPIATLIGDDGTTIRELLRRAMTSSDNTCNDILLRYVGGP +EAVRDFIARKGLGAIRFGPGERLLQAGYIADPPDGATASAIAGALAKLKRGELLSPDSTD +WLISTMESSRTGRNRLRGAVPAGWSFGHKTGTGQTAGYNDVGILTAPDGKTYTVAVLIGD +TARTIRQRQELMQAVVASVVA-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. 1_1_30 TaxID=457387 RepID=F7M8L6_9BACE +-tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQKQSLETRLPIKKSDLKPYSPLRDKYPQGEMSIADLLKYTLQQSDNNACDILFDYQGGP +DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPNVYKD +FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLLGGRTYSIAVFVKD +SEENNQANSKIIANISRIVYEY- +>[subseq from] Beta-lactamase n=1 Tax=Croceicoccus naphthovorans TaxID=1348774 RepID=A0A0G3XNJ6_9SPHN +---LNDRIFQLWRAFPGRTGIAVQRVDGEWAI-AQRGGDLFPQQSVSKLWVALTALDAVD +QGQLSLDHDVRIGPGDLTLHQPIAARVRSEGMTVRDLIESAITQSDNTANDSLLRSIGGP +DAVRSFIARKDLGPIRFGPGERLLQSAYLANPVDGATPSAIASALTRLARGSLLSPESTS +YLLDVMSRTRSGPKRLKAGLPQGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLRD +TTATVPARMALMQAVSGAVAE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Alistipes onderdonkii TaxID=328813 RepID=A0A5B3GTM4_9BACT +--QFESRLDEIVSGHKAFVGVAIR-TPDGKTI--ARNDSLLPMMSVFKFPVALAVLDRMQ +REGTPLTQPISITPDLLLPYSPMRDSLPESGLTLGQLLRYTVSESDNIACDILLREAGGP +EAVEAYVRSLGIGGIRIAASEEEMHRGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA +LLQRLLCEATTGTNKLKAGLPAGTVIGHKTGSSDRTADNDAGYVLLPDGRRYCIAVFVTE +SEENDATNAAIAAAVSRAAYEYf +>[subseq from] serine hydrolase n=1 Tax=Sphingosinicella sp. YJ22 TaxID=1104780 RepID=UPI0014083E8E +------------------------------------------------------------ +------------------------------GVSARRLMDAMITRSDNRATDQLIAMLGGP +AVVDEWLRSHGVTGMRVDRTIAQLLAARRRDVRDSSTPVAMLNLLRLIDSGRVLQPHSRA +MLLDMMARCRTGSNRIRGLLPPGTHVENKTGTLN-GYTGDVGFLTLPDGQRIAVAFFARY +GS----NRPAVIASAARAIYDNf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. 20006FA TaxID=2056888 RepID=A0A197BXJ8_9SPHN +------------------------------------------------------------ +----------------------------GRPLPVRTLIDMSLTLSDNEATDALVARAGGP +QAVNDWVRAAGIRGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGRVLRPQTTA +LMLSVMERCKTGKTRLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK +DHMGHELRDRIMAEAARAAYDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SMK8_9BACT +---------------KATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIASFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNANIIARISRMVYDA- +>[subseq from] Serine hydrolase n=1 Tax=Chroococcidiopsis sp. CCALA 051 TaxID=869949 RepID=A0A2P8QIE5_9CYAN +------------NNTQLFPGMFFIDTETGTYL-NWNGDTTFAAASTIKFPILVAFFQDVD +AGKIRLDEKLTLKKELVGGGAGFQYKPLGSQFTALETATQMIIVSDNTATNLLIERLGGI +AALNQRFKNWGLTVTELRNLLPDLEGT------NTTSPKELAQLMVAVQKGDLISVKSHD +RLLNIMRRTHT-ATLLPKGLGPGATIAHKTGDIGS-MVGDVGLVDLPSGKRYVAVAMVKR +PHN-NVQAKELIRQVSRAAYQEf +>[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter dokdonensis DSW-74 TaxID=1300349 RepID=A0A1A7BF87_9SPHN +--SFEQRIAELAEPSRGRIGVAAIDLATGEEV-MVLGDQLFPMASTSKIAVAATYLEMVE +KGRYSLTSEFPLLLPVRSAFSSARAPVRQGQMPAIDLIEIMITRSSNPATDALLAAVGGP +GVVTDWVHSQGIEQFSINRDIATLVRAIHIDPRDAATPRAMVRLLAGLYRGEFLSDESRR +VLLGAMSRTVTGKRRIVAHMPEEARVSHKTGSLSN-TSSDIGIIESPDGRAIAVAIYVTG +QG-TRLAREERIAAIARALYDGf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. S-NIH.Pt15_0812 TaxID=1920129 RepID=A0A430BIG2_9SPHN +--ELQARIDSIAAGFRGRFGIAIRAVDDGWTV-EHTARQRLPQQSVSKLWVAMTVLDQRD +QGRVRLDDPIVVRPEDLTLHQPIAFLVKAGGTTVGGLLTRALTQSDNTANDRLLTLVGGP +SAVRRMIQAKRLGEIRFGPGERQLQARYVADPPDGAAPLAIADALARLARGEILSETSTR +ILLDTMASSVTGRARLRAALPPGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYALAVMIGD +STRPIRERQMLIQAAAAALTQY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RLK4_9BACT +------------------------------------------------------------ +--------------------------------------AAALQYSDNTAMNKMISYLGGP +EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA +QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ +PQQGAKSRKEVLAAAAKIVTE-- +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00099A31FC +---LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQGFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNSAALLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDESEKIISDIGRATYDYy +>[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=A0A1H7W616_BACT4 +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLNYTLQQSDNNACDILFQYQGGV +DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGRAYSIAVFVKD +SEENNQENSKIIADISRIIYEY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingosinicella sp. GL-C-18 TaxID=2116704 RepID=A0A2P7QNW1_9SPHN +--ALDMQIRTIGQAFNGDIGIAVEDVQTGWTT-AYDGNTYFPQQSVSKFWVALTALDKAD +RGELSLSRPVTLTKSDMTVHQPVAAQIGPNGTTITALMTRALQQSDNTCNDAVLWRAGGP +DAVRSFLRDKGISGIRFGPGERRLQSKYIASPMDGATPLGIVDALARLKRGELLSPASTD +RLLSIMSNTKTGPQRLKGGLGAGWRLAHKTGTGQQAGYNDIGILTAPDGHSYAVAVMIRR +TSAPLPERMAAMQRTVRSVI--- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI000B3560F8 +--SLLKEINNITKGKKATVAVSVSGIEDNFQLsNNNGQLKMPMMSVSKFHIALAVLNQAD +KGNLTLDQKILVKKSDLHEWSPIREKYPQGNLPLSEIIYYTVAQSDNNGCDILLRLLGGT +QAVQKFVNSKGIKNIQIKHNEEEMHTKVQVLYENYTTTSSMVKTLKSFYKNMMISKKSTD +FLMDIMLKTDTGMAKLPGLLP-NVKMARKTGSSGTVAENDSGIVTLDNGKHFAIAVFVKN +STESEEINYSIIAQVSKAVFDY- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas laterariae TaxID=861865 RepID=A0A239CY23_9SPHN +--SLERRIVELGRSFSGSVGIAVRDVSDGWTV-GYNADRPMPQQSVSKLWVAMTALDAVD +RGGLSLQEPVTVTRDNLTVHQPVRAMMGPNGTSYGELMRIAMTQSDNTCNDMVLRRAGGP +TAVRSMIERKGLGRIAFGPGETLLQSRYLADPMDGASAEAIAGALARLQRGELLSPASTS +RLLGLMRQSRTGPQRLRGGLAPGWVLAHKTGTGQSTGYNDVGVITAPDGRSYAVAVMIAS +TRQSIPARQQLMNEVVRAVIA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A224A9I1_SHIFL +----------------------------------------------------------SE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGT----------------------- +----------------------- +>[subseq from] Beta-lactamase homolog BlaZm n=5 Tax=Macrococcus TaxID=69965 RepID=B9EC94_MACCJ +--KIKEDIKVIENKYNIQAGVYVNDLTDKQKL-SYNEELLFPYASTFKVINSALLIEKLG +--MNNLDKEVKVSERDIVLYSPIIEKYKNKNVSLKMLIEAALLYSDNTANNLIIEELGGL +KEVEKRLSALGIKGVNVNRKEVALNFYDPKKNEDTISAKNMSKALIKMLTGDVLEYKEQI +FLIDLMKKNKTGTTLIKKGMDKKFIVGDKSGQGNYGVRNDIAVVYKKQSKPIIVVVFTKA +KNEKQKPSDTPIVEISKVI---- +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. H050 TaxID=1759072 RepID=A0A0W1DT47_9SPHN +---LNDRLYALWRSFPGKTGIAVQRIDGEWAL-AQRGGDLFPQQSVSKLWVAMAVLDAVD +NGRMTLDQRVRIGPEDLVVHQPLASRVQAQGMSVRDLIETAITQSDNLANDSLLRTVGGP +HAVRAFVSRKDLGSIRFGPGERLLQAKYLADPVDGASPSAIASALTRLARGTLLSPQSTD +YLIGVMSRTKSGPKRLKAGLPPGWTFVHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGS +TTSSIPARMQLMQAVSGAVAE-- +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A0C5XYW9_SPHYB +------------------------------------------------------------ +----------------------------GRPLPVRTLIDMSLTLSDNEATDALVARAGGP +QAVNDWVRAAGIRGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGRVLRPQTTA +LMLSVMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK +DHMGHELRDRIMAEAARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L6KSR0_9BACT +--ALKQRLEALVKGKDGRVGICAQD-QSGTMV-CIRGEERFSLQSVVKLIVGAAVLDAAD +RGLADLKAPIVVKPENLSLVQPLAKIVEREGTNADDLVRRAIVDSDSAAVDILIERLGGP +AKVDQFAEGKGILGIRIDRDERHLQTAYQKDPRDTATPRAMTAFLAALMNGKLLAAGSTQ +RLLAIMGETVTFPDRLRAGTGEGWSVAHKTGTSRNAATNDVGILTAPDGGKIAVAVFVAD +SRETPTQRSAIIAGAAQAVTEAy +>[subseq from] Beta-lactamase n=3 Tax=Bacteroides cellulosilyticus TaxID=246787 RepID=A0A5M6AF75_9BACE +-qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYTISKSDNNTCDILIEYVGGI +DQVNEYVKSLGIKDCNLAATETLMHTS-GDTDLNWSTPEEVVRLLNIADKQPLFGTQYKD +FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQETDADNAAIIASISKIVYDT- +>[subseq from] Beta-lactamase n=1 Tax=uncultured Bacteroides sp. TaxID=162156 RepID=A0A3G2C7C6_9BACE +-qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI +DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD +FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQETDVDNAAIIASISKIVYDT- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium RIFCSPHIGHO2_01_FULL_65_20 TaxID=1802169 RepID=A0A1G3JUE2_9SPHN +--GLRDELQELWRTFPGKTGIAVRRIDGDWVV-GQRGGELFPQQSVSKLWVTMTVLEKVD +RGELTLDQQVTITPDDLTLHQPLAARVSREGETVRSLINEALTASDNSANDALLRTAGGP +AAVQDFLRRKGLANIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQSSTR +LMLDTLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLAE +TTASIPARMQLMQAVSRAV---- +>[subseq from] LRA-5 n=1 Tax=uncultured bacterium BLR5 TaxID=506522 RepID=B5L5W7_9BACT +---LTERLSSIINAAGGDIGIAVIHVETGHTT-AIQGTTQLPLYSVFKLPLAIAVLKEIE +ENRLQLDRKVRVTPADVAPTANAAMWRRPIDRTVAQLIEVSIIRSDNTSSDKLLQLVGGP +AAVTHRMRALGFPNIEIVSTVREFSEN--RTRPNTGSAEDLARLLVQLQKGELLQPQHSA +LLLGFMHRATTGTERLRGSLPVGTPVADKTGTGDAGVTNDVGIITLPKGGHLAIAVLISG +SKLSPAAQEKLIAEIARAAYDA- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium fuliginis ATCC 27551 TaxID=1208342 RepID=A0A5B8CM55_SPHSA +------------------------------------------------------------ +----------------------------GRPLPVRTLIDMSLTLSDNEATDALVARAGGP +QAVNDWVRAAGIRGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGRVLRPQTTA +LMLSVMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK +DHMGHELRDRIMAEAARAAYDYf +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter aestiaquae TaxID=1509367 RepID=UPI00136E2408 +--DFEKRIAQIADGGKGRIGVAAIDLATGKQV-SVLGDQRFPMASTSKVAIAAVFMAGVD +QGRWSLTSEYALLRPVRSAYSSKRAPVRKGEISAREHLDLMISKSCNACTDTLLRVVGGP +AAVNAWMRSVGIEGFELSRDIATLVRATVIDTRDSATPLAMARLLAGIYQGEWHSKYSRD +IIIGAMERTTTGKKRMRSGLPLSANVAHKTGTLNR-TASDIGIFQTPDGRTIAAAIYVTG +QSASRRMRDERIAQIARALYNGy +>[subseq from] class A beta-lactamase n=1 Tax=Propionibacteriaceae bacterium NML 150272 TaxID=2016504 RepID=UPI000B96B17C +----AALIADLERRHDVRIGLSAAALTRGRRL-DHRADERFLMLSVFKAIAAAAVLDGIT +PDPKVLDRPVFLPPEAICEPAWFAEQIAARRPSVAEVCRAAIQLSDSTAANALMSLTGGP +DSITRFARDNGDPVTQLTEWEPELNT--PDGDRNTTSPRAIGALFAAMIVGRALRTPARR +RLTDWMLGNQTSDQRFRAGLPAGWTLADKTGSGIDATANDVGIAFDPAGNAYQLAVLTSS +PRPDTERVNEIFAILAREAL--- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. SA916 TaxID=1851207 RepID=A0A2K0XTM1_9SPHN +------------------------------------------------------------ +----------------------------GRPLPVRTLIDMSLTLSDNEATDALVARAGGP +QAVNDWVRAAGIRGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGRVLRPQTTA +LMLSVMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK +DHMGHELRDRIMAEAARAAYDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Blastomonas natatoria TaxID=34015 RepID=A0A2V3UVL4_9SPHN +--GLRDELQELWRTFPGKTGIAVRRIDGDWVV-GQRGGELFPQQSVSKLWVTMTVLEKVD +RGELALDQEVTITPDDLTLHQPLAARVAREGETVRSLINEALTASDNSANDALLRTAGGP +GAVNDFLRRKGLSNIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQASTR +LMLDTLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLAE +TTASIPARMQLMQAVSRAV---- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. SCN 67-18 TaxID=1660141 RepID=A0A1E4JFD2_9SPHN +----NREIGRLGAGFDGRAGIAVLDIDAGWSA-SFNGDQPMPQQSVSKLWVAVAALDALD +RGAMRLNDPVTVTRADLTLHQPIRANVGAGGTTIGALLNQAMTRSDNTANDMLLWKVGGP +EAVRGLLMDRGVRGVRFGPGERLLQSAYLDDPMDGATPLGIVDGLAKLQRGRLLSPASTR +LLINTMTESRTGPQRLKAGLGAGWTAAHKTGTGQATGYNDVAIITSPNGHSYAVAVMIAS +TRQSIPVRQKLMADVVRAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Legionella sp. km772 TaxID=2498111 RepID=A0A3S0VWY9_9GAMM +-kDLDKKIKAIEKKNNTIIGLTAIHIENNTKI-AHNNTQRFFMASTIKVPIALAFLHRVD +EKKESLNRVIKMDTKNSVPGSGSLYHIFEKKMSTQQILKHMLINSDNSASDTILHAANGP +KYVTQYMANLGFKNIVVNRSILEMFLKFQNDKRDTTTSDEMAKLLVKLQKNQILSESSTQ +LVLKIMQDCRTGRSRIRGLLPGGVKVAHKTGTWAPGFASDVGIITLPNNGHVAIAVYVKS +KSASDYPRSRSIALASRAIYDYf +>[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. SG720 TaxID=2586998 RepID=UPI001448689A +--AIQQRVAAIAAAARGRVGVAAMDLDGGGQV-LINGDMPFPMASTAKVAVAATFLQMVE +QGRFRLDQQLPMMMPVPEPRNLVAMVRPGPVYTAQTLLERMITRSDNHATDGLIAAVGGI +GAVNRFLVQTGISGQHLDHTMATLVRARAIDTGTSSTPRAMIALLSAIDRGGALSPQARA +VLLDTMTRTSTGKNRIRAGLPEGVLLAHKTGTLA-GVTDDVGIVRMPDGRHLAMAIFVAG +PE-NHTAQAGMISRIAATLYEGf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides clarus TaxID=626929 RepID=A0A412YPK6_9BACE +-qTLESKIGDFLKGKKAMVGVAVL-TDRNKIL-LHNNKMNYPLLSVFKFHVALAVLDKMN +KQETPLDHIVHVKASQLQPYSPLRQKYPNQDISLGELLRYSISLSDNNACDILIEYAGGI +GHIHQYINKLGVCDFNLSETEDSMHRNPSKTYLNWSTPAEMVRLLEIADKKELFDPIYKD +FLWNTMIATSTGSNKLKGLLPSNAIVGHKTGSSDRNADNDAGVVIMPDGKKYYIAVFVMN +SRETDDENAAIIARISRMAYDEy +>[subseq from] Beta-lactamase n=1 Tax=Coprobacter secundus TaxID=1501392 RepID=A0A0B2JH50_9BACT +-nELRKELEAVIRDKKARVGVAVIY-DGKDTL-TLNNEYRYPMMSVFKFHQALSVLNDLD +SGGLPLDTEIFVKKSDLHPYSPLRDSVPQGNMTVAELLRYSITLSDNNACDILFKHFGGT +GKTEKYMKGLGIEKIVIQFDENEMHTSVDAERANWTTPLEAAKVMDIFLRNKLFSVSLSD +FLENLLICTSTGADKIKGGLPSGVIMGHKTGSSSRTADNDLAFVQLPDGKRYTIAVFVMD +ADEDDKTIAGIISQISRHVYDFy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacteriaceae bacterium DW12 TaxID=1550091 RepID=UPI00053251BB +----NIQVDSILRDKKAHIGVHILHLKDGVEL-QVNGENTFPMQSVFKFPIALAVLDMLQ +QKQLPLDHGIYVAKKDLLLWSPLRDQYPEGNLPISKLLAVMVSQSDNNACDILLRWIGGE +DVVQRYIQKLGISDMKIVANEEAMHRDWNVQYLNYSSPKSSNELLVKAYKSNLLSPQYLD +FFWKVMTETSTGKKRITAPLPKGSIVSHKTGSSGTGAVNDVGIVQLADGTAYAISVFVVN +SLEDESTNEQIIAAVSQITYL-- +>[subseq from] Beta-lactamase n=1 Tax=Legionella santicrucis TaxID=45074 RepID=A0A0W0Z3Q9_9GAMM +--ELSKRINAIEKNSRTVMGVTAIHIEKNKII-SHNSNQRFFMASTVKLPIALAFLHRVD +ENKESLDRVIKMDTKNSVPGSGTLHYLFEKKMSLKQVLIHMMRNSDNSASDTILKVTNGP +KYVASRMSALGFKNIFVNRSILEMFLRFQNDMRDTTTSDDMAKLLVKLYKKQALSESNTK +LLIDIMEKCRTGRSRIKGLLPAHVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS +QSASDYPRSRAIALASRAIYDHf +>[subseq from] Class A beta-lactamase n=1 Tax=Novosphingobium sp. FSY-9 TaxID=1908524 RepID=A0A3S2Y7A0_9SPHN +-------------------------------L-GFWQHQRFAFCSSFKLSLAALVLDGAE +KGEWRLEEKLAYSAADLLPNSPVTQANLALGMTIEALAEAAQKFSDNAAANILLRKIGGF +DRLNQFWWGLGDTVSRLDDYETALNRVPLGSVRNSTTPAAMALNLVKLFYQGALSPAAAA +KLKGWMHDTATGAKRLRAGLPADWWAGDKTGTGLRGTYVDLAWVEPPKLPPFAIAAFYQP +PKPTDPNAEAILAEVGRMVA--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis fribergensis TaxID=1515612 RepID=A0A0A7PJX3_9SPHN +---LNDRIYELWRSFPGKTGIAVQRIDGEWAL-SQRGGDLFPQQSVSKLWVTLAVLDAVD +QGRMTLDQRVRIGPEDLVVHQPLAARVRAEGMSVRDLIETAITHSDNLANDSLLRTVGGP +NAVRAFIAKKDLGSIRFGPGERLLQANYLANPVDGASPAAIASALTRLARGTLLSPESTE +YLQDVMSRTRSGPRRLKAGLPPGWKFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGT +TTSSIPARMALMQSVSSAVAEY- +>[subseq from] Serine hydrolase n=1 Tax=Thermosynechococcus sp. CL-1 TaxID=2583530 RepID=A0A5C2M772_9CYAN +--NLQQQIQQLVSRQNLAAGLYFFNLDSGASL-NVGGDAVFPAASTIKFPILVAFFKAVD +EGRVTLHERLTMRPDLIASEAGTLQQKPNSQYPALEVADLMITISDNTATNMIIDRLGGA +AVLNQQFQEWGLENTVINNLLPDMKGT------NTTSPRDLATLMLKIGQGEIVSPRSRD +RLLDIMRRTVT-NTLLPAGLGKGATIAHKTGDIGI-VVGDVGMVDMPNGQRYVAAMMVKR +PYND-PRGSELIRQVSRMAYQAf +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sp. MM-1 TaxID=745310 RepID=M4SBW5_9SPHN +---LEARIATLGQSFAGSVGIAVRDVSTGWAV-SYNAQRPMPQQSVSKLWVSMAVLDAVD +RGTISLSEPVTVRRDNLTVHQPVRAMMGANGTTYGALMRIALTQSDNTCNDMLLRRVGGP +DAVRGMILRKGLGRIAFGPGETLLQSRYLADPMDGATAEAIAGALARLKRGELLSPASTR +LLLTTMGDSRTGPQRLRAGLAPGWTLAHKTGTGQATGYNDVGVITAPDGRSYAVAVMIAS +TRQPIPVRQRLMADVVRAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Calothrix sp. NIES-4101 TaxID=2005461 RepID=A0A1Z4QVM8_9CYAN +--TLRTSIQSLAAASNLTPGVFIADLDTGSYV-DFNGGAMFSAASTIKIPILVAFFQDVD +AGKIRLDETIASTKTTIATGSGIQYKPVGTSYSALEIATKMITISDNTATNMLIERLGGI +EVLNQRFRSWGLNTTVIRNPLPDIEGT------NTATPKELAHLIAVVTKGNLVSMQSRD +RILDIMRRTVK-DNLLPAGLSDGATIAHKTGEIG-AILADVGLVDLPTGKRYIAAVMIQR +PRND-ASAEKLISSISRAAYQQf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas fennica TaxID=114404 RepID=A0A2T4HQ24_9SPHN +---LEARIATLGQSFAGSVGIAVRDVSTGWAV-SYNAQRPMPQQSVSKLWVSMAVLDAVD +RGTISLSEPVTVRRDNLTVHQPVRAMMGANGTTYGALMRIALTQSDNTCNDMLLRRVGGP +DAVRGMILRKGLGRIAFGPGETLLQSRYLADPMDGATAEAIAGALARLKRGELLSPASTR +LLLTTMGDSRTGPQRLRAGLAPGWTLAHKTGTGQATGYNDVGVITAPDGRSYAVAVMIAS +TRQPIPVRQRLMADVVRAVVA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=C3VJU8_STAAU +------ELNDLEKKYNAHIGVYALDAKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTATNKIIKEIGGI +KKVKQRLKELGDKVTNPGRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQA--------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. H038 TaxID=1759066 RepID=A0A0W1EQP5_9SPHN +---LNERIYELWRAFPGKTGIAVQRIDGEWSL-SQRGGELFPQQSVSKLWVALAVLDAVD +QGRMTMDQRVRIGPEDLVVHQPLAARVRAEGMSVRDLIETAITHSDNLANDSLLRTVGGP +AAVRAFIAKKDLGSIRFGPGERLLQANYLANPVDGASPAAIASALTRLARGTLLSPESTE +YLQGVMSRTRSGPRRLKAGLPPGWQFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGT +TSSGIPARMALMQSVSSAVAEY- +>[subseq from] serine hydrolase n=1 Tax=Nostoc sp. B(2019) TaxID=2690446 RepID=UPI0013914311 +----KNAVQNLAANSDLTPGAFLVDLDTGAYV-DVNGSASFPAASTIKVPILVAFFQDVD +AGKIRLDEMLTMQQEMIAGGSGNLQYKPAGTYSALEVATKMITISDNTATNMLIAHLGGR +EVLNQRFRSWGLTTTTIRNLLPDLQGT------NTTSPKELGNLIAIVNQGNLVSMRSRD +QILDIMRRTEK-DNLLPSGLGAGARIYHKTGDIGT-MLADAGLVDIPTGKRYIAAVMVQR +PNND-PRAEKLISSISRSAYEQf +>[subseq from] Class A beta-lactamase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A5C8DCP7_9BACT +--SLRVNINRIAQRINARVGVSISLIEAGDSL-SYRGEERFPMMSVYKFPIAIAVLKELD +RGTTFMERYLLLPKDSIYTGEEETYSFPGGKITIGQLLTLMLVQSSNTACDQLLYLLKGP +ANMQPYLNDLDIQDMAIANTEKEINIDSLLRFDNWSTPDEMRGLLAIAYTGDYLSKKNHD +FLWDKMTETVVGANRIKGLLPKNTVVAHRTGTGY-GSYNDAGIITLPSGKHLAIVVFISE +AQENPEKCNEAIARIAKLAWDYy +>[subseq from] Beta-lactamase class A n=2 Tax=Microcoleus sp. PCC 7113 TaxID=1173027 RepID=K9WCY8_9CYAN +---LKSQIQTLAANNKLQPGVFIVDINTGTYI-DINSRSPVPAASTIKVPILVALFKEVD +EGKIRLDESLTLQSEMIATGSGNLQQKPGAKFTVLELATKMITISDNTATNMLIARLGGI +EALNQRFRAWGLTTTVLRNALPDLEGT------NTASPQELAALMAMINQGQLVSLPSRD +RILSIMQSNEI-NSLLPQGLGSGAIIAHKTGNIG-ALLADVGLVNMPSGKSYIISVMVQR +PFND-DSAQELIRKISKTAYEYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=A0A2L0NG86_STAHA +-----------------------------RILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLT----- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SGA7_9BACT +-nELRKELEAVIRDKKARVGVAVIY-DGKDTL-TLNNEYRYPMMSVFKFHQALSVLNDLD +SGGLPLDTEIFVKKSDLHPYSPLRDSVPQGNMTVAELLRYSITLSDNNACDILFKHFGGT +GKTEKYMKGLGIEKIVIQFDENEMHTSVDAERANWTTPLEAAKVMDIFLRNKLFSVSLSD +FLENLLICTSTGADKIKGGLPSGVIMGHKTGSSSRTADNDLAFVQLPDGKRYTIAVFVMD +ADEDDKTIAGIISQISRHVYDFy +>[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. AG162 TaxID=2572910 RepID=A0A542Q6H5_9BACL +---WQQAVENVLKEAPGIYGIAAVHLETGETV-GHLDEELFQLASTFKIPIMVTLMREVE +AGQIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELIGGI +DKVNEHMHELGLSQIHLRHNCWVLLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE +LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVND-VVNDAGIIYLPEGKGMIAITALSR +GVTDKEAAELTIARVAKAIYE-- +>[subseq from] Serine hydrolase n=1 Tax=Chroococcidiopsis sp. TS-821 TaxID=1378066 RepID=A0A2S6V5K6_9CYAN +--SLKTTVEQLAAQKNLLPGVFFLDLDTGAYL-EINGNSTFASASTIKVPILVAFFQDVD +AGKIRLDERLTLKKELVGGGSGDMQKPLGTQFTALETATKMITISDNTATNLLIERMGGA +AALNQRFLSWGLPATQIRNLLPDLEGT------NTTSPRDLAHLMALVDDGKLMSLRSRD +RLLDIMRRTVT-NTLLPRGLGEGARIAHKTGDIGS-LVGDVGLVDMPNGKRYIAVAMVKR +PHND-GRAQELIRQISRAAYQE- +>[subseq from] Beta-lactamase n=2 Tax=Legionella shakespearei TaxID=45075 RepID=A0A0W0YKX7_9GAMM +--DLAKKISAIEKKANVIIGITAVLIEKNKVM-SHNGNKRFFMASTIKLPIAIAFLHRVD +EKKDSLKRIIKLDYNNSVPGSGSLYHIFEKKMSSQQIMNHMLINSDNSASDTLLDAVNGP +QYVNKRMSALGFKNISVNRSILEMFMRFEKDARDSTTPDDMANLLVKLYNGEALSESSTD +LLIKTMEKCRTGRSRIKGLLPPNVKVAHKTGTWAYRFASDVGIITLPNKGHIALAIYVKS +QSASDYPRSHSIALASKAVYDHf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas asaccharolytica TaxID=40681 RepID=UPI0008357497 +----TALVPSLTRDFGGKVGIAVMSIDDGWTV-TSNGDMKLPQQSVSKLWVAMTVLDLRD +QGKLTLDDPYTVRKDDLTLHQPIAALVKDDGTTVGELLQRALTQSDNTANDCLLRLAGGP +TAVRAFLTKKGISDIRFGPGERLLQSRYVADPPDGAAPRAIVTALARLKKGELLSPTSTQ +YLMSTMESSRTGRQRLRGAVPEGWTFGHKTGTGQTAGYNDVGFLISPNGKAYAIAVMIGD +TPKTIPERQQLMQAVV------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=F1DI11_ECOLX +------------------------------------------------------------ +AQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLSHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTN--------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingosinicella sp. YJ22 TaxID=1104780 RepID=UPI00140D601B +-sALEERVQELGHSFPGEVGIAVRDIETGYVA-SWNGGRLFPQQSVSKFWVSLTTLDAVD +RGRLDLDRRVTVTRDDLTLSQPIAQQVDADGTTLRDLMTRAITRSDNTANDFLLWQAGGP +EAVRAFISRTGIEGVRFGPGERLLQSDYIEDPQDGASPLGLTQGLAMLQRGELLSPASTR +HMISTLRATRTGPNRLAGGLAPGWTIGHKTGTGQQAGYNDIGIITSPDGRHYALAVMIGR +VSVPLGVRMTLMNNVTRAAIQY- +>[subseq from] uncharacterized protein LOC115123033 n=1 Tax=Oncorhynchus nerka TaxID=8023 RepID=UPI0011312053 +---AAAALADLERDAGGRLGVCAIDTASGRII-EHRSGERFPFCSTFKAMLSAAVLAQSV +DRPGLLQQRVTYTKADLVNYSPVSEKHVGVGMTVAALCEATIQYSDNSAANLLMKLIGGP +SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMR-------------- +------------------------------------------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Legionella sp. 13.8642 TaxID=2259147 RepID=UPI000E205FA1 +--ELSQRINAIEKNSRTVMGITAIHIEKNKVI-SHNSNQRFFMASTVKLPIALAFLHRVD +ENKDSLDRVIKMDTKNSVPGSGSLHHLFEKKMSLKQVLIHMMRNSDNSASDTILKVTNGP +KYVASRMSALGFKNIFVNRSILEMFLRFQNDTRDTTTSDDMAKLLVKLYKKQALSESNTK +LLIDIMEKCRTGRSRIKGLLPANVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS +QSASDYPRSRAIALASRAIYDHf +>[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=A0A1T3FLP1_ELIME +-nELKKRIENIITGKKADVGVSIIGGNKNDKV-QINGNQLYPMLSTFKFPIALTVLHKVE +KGELKMSQKIFIKKEELLDWSPFLEKYPQGNITLEDALMWMMCYSDNNLTDILIRLIGGT +DTVQKF---IGTKDFIIKNDEEDMHKDWDSQFINKITPNRATQLLDKFYQGKILNGVNTK +WLYEAMLNNKTGLKRLKGKLAADIKVAHRSGTSFTGAINSYGIIELPKNKKIVITVFVHD +TYENFNDSEAIIADIAKTVYDYy +>[subseq from] Beta-lactamase class A n=1 Tax=Edaphobacter aggregans TaxID=570835 RepID=A0A428MMG1_9BACT +--PLRQQIRSIAAEAHGKVSVACSLPGSSLNC-DLDPTAQPPMQSVFKLPLALAILHQVE +QGKFSLDQPIRFLREDLILYSPLQDKYPDAGVPLRTLLQLTVSLSDNTAADILLRLAGGT +KVVDEYIASLGITGFHLEDGERALHRQVALQYRNWFEPQGAVQLLRRISDHSPLTAEHTE +LLLGWMRPAVP-TKRLEGDLPKGTSVAHKSGTSDAHATNDIGLIAMPDGRQLAIAVFVTD +STADQATREKVIAEIGRAAYD-- +>[subseq from] HGG-1 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=C8C144_9ZZZZ +--DLTSDIQEVIKGKKAQVGVAVLY--KDDAF-TANSDDQYPLMSVFQFHIALAVLKKME +KEGIPLTAVVTLGPSDIDTWSPMYKKYKSKKLSYGDLINYMVSQSDNNACNWLINFVGGI +QNVNDFIKNLGIDRIQLIETEKSMEQDIRKSYNNWSTPLSVTQLLRKVYTEKVLSDEHFA +FLEKAMLASASGKDKFRAGLPKEVEVGHKTGMSYRTCDADVGVIYMPGGEKCYLAVLVKD +SKETDAANAKIMADIAKKVYSHy +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium haifense DSM 19056 TaxID=1450526 RepID=A0A246BAJ8_9FLAO +-aELKKEISKITEGKKATVAVSVKGIDFPFEFnNENLRKKLPLLSVFKFHIALATLDMVD +KGRLNLNQKIFIKKEDLHEWSPLREKFPNGNMTLSELLKYMVANSDNNATDKILNVIGGT +QIVQNFIDSKKIKDFQIRVNEERMNSAWKSMYENWSTTESLVKSLIKFDKAKILPKTSRD +LLMNIMLGTTTGTNKIVEQLPKGTPVAHRTGSSGTVAENDIAIITLPNGKKYAIAVLVSD +SRESYEVNCKMISDISKTVWNH- +>[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia sp. 2-6 TaxID=2575699 RepID=A0A4V1DZD6_9FLAO +---LKKTLESIISGKKSTVGVSIMDPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMHQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAIFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium PASS1 TaxID=2015579 RepID=A0A257DH12_9SPHN +----ENLIQDQWRLFPGRTGVAIMRVDGGEWVlGRRMDELFPQQSVSKTWVALTVLDMVD +QGKLRLDQKVRITRDDLAVHQPIRDQVIANGVSVLNLLEQAIRASDNTANDSLLRTVGGP +QAVTSFIVRKNLGAIRFGPGERALQSRYLNDPIDGASPQAIVRALARLAKGELLSASSTR +LMLDIMSRTSSGPNRLKAGVPAGWSFLHKTGTGQSTGYNDIGIMTAPDGTRYAVAVMMGS +TTASIPQRMTFMQFVSRAVASY- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=A0A0D5BL05_ELIMR +htSILNDINAVTKDKKATVAVSVLGIENEFQFsNNNGNLKMPMLSVFKFHIALAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT +RTVQKLMDVNGVKNFQIKYNEEEMHKNVKALYANYTTTASMVKTLKAFYKGMFLSKRSTI +FLMDIMTRTNTGMAKLPGLLP-KVKMARKTGSSGKMAENDSGIVTLVNGKHYAIAVFVKD +SMESEEVNCGMIAQISKIVWDT- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0D5CA60_KLEPN +----------------------------------------------------AAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGS---------------------------- +----------------------- +>[subseq from] Beta-lactamase n=3 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SFD7_9BACT +-qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI +DQVNEYVKSLGTKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD +FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQENDADNATIIASISKIVYDT- +>[subseq from] Class A beta-lactamase n=1 Tax=bacterium TaxID=1869227 RepID=A0A4Q3VHP6_9BACT +--NLAAEIQKIEASLGARIGVAAQRF-GGARF-DYRGAERFPLQSVFKYPLAVAVLRAVD +VGKLKLDGAVILDRSNLSVYSPLGETVLAKGTTWAELVKRAVSKSDNTAADVLMRRIGGP +STLTATLRSLGVTGVRIDRYESRLQCRALAEVRDTSTPNGMLTFLRGYDTGGWLSALSKN +FLDRTLFETMTGPDRLRAGFGPDWKLRHKTGTGGYGARNDVGIATAKDGSKIAIAVFLTG +ASGRDKVRDAAIAKVTRLVRD-- +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium HGW-Alphaproteobacteria-7 TaxID=2013670 RepID=A0A2N3B5C3_9PROT +--SFEQRIAELANADQGRIGVAAIDLATGEEI-MVLGDQLFPLASTSKIAIGAAYLEMVE +QGRYSLTSEFPLMMAVRSASSPKAPVREGQYMPAIDLIEIMITRSSNPATDAMLAAIGGP +AVVNDWVRRQGINDFSINRDIATLVRANHIDPRDAATPRAMVRLLAGLYRGEFLSDQSRQ +VLLGAMSRTITGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGIIETPDGRAIAVAIYVTG +QG-TRLAREQRIAAIARALYDGf +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonadales TaxID=204457 RepID=A0A292ZJK4_SPHSA +------------------------------------------------------------ +----------------------------GRPLPVRTLIDMSLTLSDNEATDALVARAGGP +QAVNDWVRAAGIRGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGRVLRPQTTA +LMLSVMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK +DHMGHELRDRIMAEAARAAYDYf +>[subseq from] Beta-lactamase n=2 Tax=Legionella steelei TaxID=947033 RepID=A0A0W0ZRM3_9GAMM +--ELIRKLNVIEKKSNTIMGITAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD +EKKDSLNRVIKMDARNSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP +KYVAQRMSALGFNNIFINRSIMEMFVRFENDTRDTTTPNDMAKLLVKLYKKQALSESSTN +LLMKIMEQCRTGRSRIRGLLPPSVKVAHKTGTWSYRFVSDVGIITLPNNGHIAIAVYVKS +KSASDYPRSHAIALASRAIYDHf +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000C9AADFE +---LKKTLESIISGKRATVGISIMGPNTKEVT-RINGDQMLPMLSTVKFPLALTVFHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLVGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus formosus TaxID=54913 RepID=A0A220MKH4_9BACL +---WQQAVENVLKEAPGVFGIAAVHLETGETA-GHLEEELFQLASAFKIPIMVTLMREVE +AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI +DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE +LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR +GVTDKEAAELTIARVAKAIYE-- +>[subseq from] Beta-lactamase TEM n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2P1BNE8_KLEPN +------------------------------------------------------------ +-------------------------------MTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFAQ-HGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Uncharacterized protein n=2 Tax=Sphingobium quisquiliarum TaxID=538379 RepID=T0H4G6_9SPHN +---LLGEFERFAALTDGTVGIAVRDLHSGQSI-GINNDTLFPMASTYKVAVAGKIFSMAD +AGALNLDERLP---------------RLGTPLPVTALLELMLTRSDNEATDVLVARAGGP +QAVNSWLQSIGIHGQRVDSNTAQLLEAFAADPRDTSTPRAMNDLLAAIHHGKALKPGSSA +ALLAIMARCKTGKARLTGMLPPGTQIAHKTGTLN-GLGNDAGLIALPDGRTFAISVFVMK +DHRGHVLRDRIMAEVARAAYDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dysgonomonas sp. ZJ709 TaxID=2709797 RepID=UPI0013EDBDEF +---LRHNIQKIIENKQATIGVGLI-VDGKDTL-TINNNHNYPTLSVYKFHLALAVLNYMQ +INNISLEHEIFIAKDDLLPHSPLRDTNPDGNMSIADLIKYSVAKSDNNACDILFKYIGGT +TKVDQYIKSIGIENCHIAATEAKMHEQFENQYLNWSSPLSAVRLLEVFRSNKLLSPIYQD +FLWKTMVETTTGSNKIKSLLPAKTLVAHKTGSSFRNAENDIAIIQLPDGKYYSLAVFITD +SMENDDINAKIIADISKTVYDY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Thalassocella subtropicalis TaxID=1123952 RepID=A0A2L0NG97_9RHIZ +-----------------------------KILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDKRDTTMPVAMATTLRKLLTGELLT----- +------------------------------------------------------------ +----------------------- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia ursingii TaxID=1756150 RepID=UPI0009990A4C +--ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNQVD +RGNLALDQKILVKKSDLLEWSPIREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGV +KTVQKLMDVNGVKNFQVKYNEEEMSKKVQAPYANYNTTASMVKTLKAFYKGMFLSKRSTA +YLMEIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLGSGKHYAIAVFVKD +SMESEEVNCGMIAQISKVVWDA- +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000C6C8F22 +---LKKTLESIISGKRATVGISIMGPNTKEVT-RINGDQMLPMLSTVKFPLALTVFHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingosinicella sp. BN140058 TaxID=1892855 RepID=A0A4P6FKG4_9SPHN +-rALDAQIRAIGNTFNGDIGIAVKDVQTGWRT-AFDGNTYFPQQSVSKFWVALTALDKAD +RGELSLTRPVTLTKSDITLHQPVAAQIGPSGTTITSLMTRALQQSDNTCNDAVLWRAGGP +EAVRAFLRNKGISGIRFGPGERLLQSKYIASPMDGATPLGIVDALARLKRGELLSPASTD +RLLSIMSNTKTGPQRLKGGLGAGWRLAHKTGTGQQAGYNDIGILTAPDGHSYAVAVMIRR +TSAPLAERMAAMQRTVRSVI--- +>[subseq from] Beta-lactamase n=1 Tax=Legionella parisiensis TaxID=45071 RepID=A0A1E5JRV6_9GAMM +--ELIKKIRDIERKSNTVMGITAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD +ENKDSLNRVIKMDSRYSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP +RYVAKRMNALGFKNIFINRSIMEMFIRFEKDIRDTTTPNDMAKLLVKLYKKQALSQSSTD +LLMKIMEQCRTGRSRIKGLLPANVKVAHKTGTWSYRFVSDVGIITLPNKGHVAIAVYVKS +KSASDYPRSRAIALASRAIYDHf +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI0004E3CA50 +---LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYSTLLLQEFSNGKILNKAHTQ +WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter sp. YJ20 TaxID=1104773 RepID=UPI00140C5D14 +-tALERQVAQLTANAKGRIGVAAIDLTTGKQV-SVLGTQRFPLASTSKIAIAATFLEGVD +QGRWRLDDKFPMML------SPTQ---EGRSLSARELIELAITRSSNEAADGLLRVVGGP +RAVNDWVHRAGIREFSIDRYIDTLVRAQSIDVRDSATPLAMVNLVKGLHDGRWLSQSSRN +VLLGAMGRCKTGPQRIPGQMPDGVMVAHKTGSLYN-TSSDVGIVTGPDGHAIALAIYVTG +GRNDHKYRFEKIGTIARVVYDGf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A7U967_ECOLX +------------------------------------------------VMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKT------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas panacis TaxID=1560345 RepID=A0A1B3ZG99_9SPHN +--ALARSINAVARSFDGRVGVAVRSIDKGWTV-ESNGDVRLPQQSVSKLWVAMTVLDLRD +SGRLTLDDPITLTRNDLTLHQPVASLLKNGETTVGELLRRALTMSDNTCNDRLLRYVGGP +SAVRDFIARKGLGNIRFGPGERLLQSRYVADPPDGAAPRAIADALARLKKDELLSPNSTA +FLISTMESSKTGKQRMRGAVPVGWSFGHKTGTGQTAGYNDVGLLMAPDGRAYAIAVMIGD +TPRTIPQRQELMQSVVQAVVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas formosensis TaxID=861534 RepID=UPI0012F99B1E +--ALANRITTLGRSFNGLVGIAVRDVQTGWTA-SYNGSLLFPQQSVSKLWVSITVMDAVD +RGRLRLDQPVTIRRDDLTVHQPIRALVGPDGTTLGALIEQAMTRSDNTANDKLLWTVGGP +EAVRSMLARNGISGVRFGPGERLLQSRYLADPIDGASPEGITLGLAGLARGNLLSPASCR +YLLGVMENSKTGPQRMRAGLAPGWTLAHKTGTGQATGYNDVGLVTAPDGRAYAIAVMIGR +TTLTIPQRQRLMSDVVRAVVA-- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium CG1_02_56_21 TaxID=1805132 RepID=A0A1J4SWN4_9BACT +--AMVSSLGKISRAYKGRVGIYIKDIETGKTW-SYNADRLFPSASLVKVPIMAAVFEKIQ +TGSMTLDTQIKLTRQKRVGGSGSLKWVRDGTLSVMEIIYKMITESDNTATRMLIDSV-GM +PYLSESFRKMGLEHTNITPEGMSLTSG-RVVRENYTTASEMAYLMEQVYEGKLVSRESSE +FMLDVLKHNKS-RSRLRRGLPLGWEIGHKTGLLRK-ACHDVGIVFSPRGD-YVIAVLTSE +VP-NYSSAKNFITRVAKLTFRYy +>[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013D7A789 +------------------------------------------------------------ +--------------------------------------RAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARLALE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides thetaiotaomicron dnLKV9 TaxID=1235785 RepID=R9HGM1_BACT4 +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLGKEVIIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD +SEENNQENSKIIADISRIVYEY- +>[subseq from] class A beta-lactamase n=1 Tax=Phyllobacterium myrsinacearum TaxID=28101 RepID=UPI00102A0948 +--ALKQRLEALVQGKDGRVGICAQD-QKGTAV-CVRGEERFSLQSVVKLIAGAAVFDAAD +RGLTDLKEPIVVKPENLSLVQPLAKIVEREGTNADDLVRRAIVDSDSAAVDILIERLGGP +AKVDQFAEGKGILGIRVDRDERHLQTAYQKDPRDTATPRAMTEFLAALMNGKLLSTGSTQ +KLLAIMAETVTFPDRLRAGTGEGWAVAHKTGTSRNVATNDVGILTAPDGGKIAVAVFVAD +SRETPTQRSAIIAGAAQAVTEAy +>[subseq from] serine hydrolase n=1 Tax=Oscillatoria sp. PCC 10802 TaxID=1173028 RepID=UPI0012DBF771 +--DLKMQLQALAAQNDLAAGAFFADLDTGAYI-DLNGSQALPAASTIKLPILIAFFQDVD +AGKISLEEPLTLREEDIAEGSGDMQDNPGRSYTALETATKMIAISDNTATNMLIERLGGA +ETLNQRFASWGLTETAIRNKLPDLEGT------NTTSPKDLGNLMAQVNQGELVSLRSRD +RLLGIMQRTEN-NTLLPQGLGEGATIAHKTGTIAS-MLGDAGIVDLPTGKRYIAAVMVKR +PDND-PRAEELIRQFSRKVYLYf +>[subseq from] Beta-lactamase n=2 Tax=Propionibacteriaceae TaxID=31957 RepID=A0A2A9GWF6_9ACTN +------LIADLERRHDVRIGLSAAALTRGRRL-DHRADERFLMLSVFKAIAAAAVLDGIT +PDPKVLDRPVFLPPEAICEPAWFAEQIAARRPSVAEVCRAAIQLSDSTAANALMSLTGGP +DSITRFARDNGDPVTQLTEWEPELNT--PDGDRNTTSPRAIGALFAAMIVGRALRTPARR +RLTDWMLGNQTSDQRFRAGLPAGWTLADKTGSGIDATANDVGIAFDPAGNAYQLAVLTSS +PRPDTERVNEIFAILAREAL--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KZQ1_9BACT +-----AAIREIVRPLKAKVGVSAVMLDTGESV-SVGDEAFYPMQSVYKFPLALSVLKRVD +QEVLNLDQKLHVTRDQLPEWSPLRDRFPQGGFPLKELLRFSVQESDNNACDILFSLIGGP +AAVQKDLKEWGVENMNVKYTEADTHRNHEWQYSNSARPSAVTFLFRMFDEGKILKKDTQL +FLWDMMASCATGAERLKGLLPKEYVVAHKTGTGGVSAINDAGIIVLPGGRRMAVTVFVMN +SKDSPAVCEGTIASVARWLCTEw +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides faecis TaxID=674529 RepID=UPI000D6509AA +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DAVNQYIHSLGVTDCAIVCTENEMHQDESLCYQNWTTPLAAARLLEIFRKEVLFPQEYKD +FIYQTMTECQTGQDRLVALLDKKVTIGHKTGTGDRNACNDIGFVLLPDGHVYSIAVFVKD +SAENNQENSKIIADISRIVYEY- +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI000B34B5CB +-nELKKRIENIITGKKADVGVSIIGGNKNDKV-QINGNQLYPMLSTFKFPIALTVLHKVE +KGELKMSQKIFIKKEELLDWSPFLQKYPQGNITLEDALMWMMCYSDNNLTDILIRLIGGT +DTVQKF---IGTKDFIIKNDEEDMHKDWDSQFINKITPNRATQLLDKFYQGKILNGVNTK +WLYEAMLNNKTGLKRLKGKLAADIKVAHRSGTSFTGAINSYGIIELPKNKKIVITVFVHD +TYENFNDSEAIIADIAKTVYDYy +>[subseq from] class A beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=UPI0009BDCC0D +--HLLAEFDRFAALSDGTVGVAVQDLQTGEVQ-SRNGDTLFPMASAYKVAVAGRILSLVD +AGSLKLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP +KAVSDFVAGLGIHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLVAYESGKALKPESTQ +LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK +DSRGHVSRDQIMAQAARAAYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=UPI0013205530 +--HLLAEFDRFAALSDGTVGVAVQDLQTGEVQ-SRNGDTLFPMASAYKVAVAGRILSLVD +AGSLKLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP +KAVSDFVAGLGIHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLVAYESGKALKPESTQ +LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK +DSRGHVSRDQIMAQAARAAYDYf +>[subseq from] Beta-lactamase n=2 Tax=Cyanobacteria TaxID=1117 RepID=K9TXP2_CHRTP +------------NNTQLFPGMFFIDTETGTYL-NWNGDTTFAAASTIKFPILVAFFQDVD +AGKIRLDEKLTLKKELVGGGAGFQYKPLGSQFTALETATQMIIVSDNTATNLLIERLGGI +AALNQRFKNWGLTVTELRNLLPDLEGT------NTTSPKDLAQLMVAVQKGDLISVKSRD +RLLNIMRRTQT-ATLLPKGLGPGATIAHKTGDIGS-MVGDVGLVDLLSGKRYVAVAMVKR +PHN-NVQAKELIRQVSRAAYQEf +>[subseq from] Beta-lactamase n=1 Tax=Legionella cincinnatiensis TaxID=28085 RepID=A0A378IMT0_9GAMM +--ELSKKIKAIEKNSHTVMGITAIHIEKNKII-SHNSNQRFFMASTVKLPIALAFLHRVD +ENKDSLDRVIKMDTKNSVPGSGTLHHLFEKKMSLKQVLIHMMRNSDNSASDTILKVTNGP +KYVASRMSALGFKNIFVNRSILEMFLRFQNDTRDTTTSDDMAKLLVKLYKKQALSESNTN +LLIDIMEKCRTGRSRIKGLLPAHVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS +QSASDYPRSRAIALASRAIYEHf +>[subseq from] serine hydrolase n=1 Tax=Chroococcidiopsis cubana TaxID=171392 RepID=UPI000D04BE3A +------------NNTQLFPGMFFIDTETGTYL-NWNGDTTFAAASTIKFPILVAFFQDVD +AGKIRLDEKLTLKKELVGGGAGFQYKPLGSQFTALETATQMIIVSDNTATNLLIERLGGI +AALNQRFKNWGLTVTELRNLLPDLEGT------NTTSPKDLAQLMVAVQKGDLISVKSRD +RLLNIMRRTQT-ATLLPKGLGPGATIAHKTGDIGS-MVGDVGLVDLLSGKRYVAVAMVKR +PHN-NVQAKELIRQVSRAAYQEf +>[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium sp. SG707 TaxID=2586996 RepID=UPI001447E78F +---------DIERQYGGRLGFAVA-FSSGGIV-NWRGHERFAFCSSFKLSLAALVLTGAE +KGEWRLDEKLPFGKGEVLFNSPALQARLGLGISMAEAAEAVQKQSDNGAANLLMRRMGGF +DRVNRFWRGLGDMVSRLDDYETALNRVPPGSLRNTTTPEAMADNLFRMFRQGALSPAVVT +RLKGWMHDTTTGAKRLRAGLPGNWWAGDKTGTGLPGTYVDLAWVEPPDLAPFAIAAFYQP +PKPTDSNAETVLAQVGQNIAQ-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=UPI000E5D3AD0 +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGEIDIADLLNYTLQQSDNNACDILFQYQGGV +DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD +SEENNQENSKIIADISRIVYEY- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1Q1S3_9ZZZZ +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVA-------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=3 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=K9DEM1_SPHYA +--HLLAEFDRFAALSDGTVGVAVQDLQTGEIQ-SRNGDTLFPMASAYKVAVAGRILSLVD +AGSLKLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP +KAVSDFVAGLGIHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLVAYESGKALKPESTQ +LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK +DSRGHVSRDQIMAQAARAAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium kunshanense TaxID=1445034 RepID=A0A328BLJ7_9CAUL +--ALQSRLDALAADYGEEVGIAVTDVQAGWTA-GVDRDRPYPQQSVSKLWVAIAVMKAAD +EGRLDPEAPLTLTEADRSVFQPVSYKIGPAGTPLSDLLRRALVESDNAANDRLMRELGGP +EGVAATLDEMGLTAVKVGAYERDLQAAYLADPPDGTTPAAITAALAALHRGELLSAASTQ +RLIGLMEQARTGPRRLKGGLPPGWTIAHKTGTGQSVGINDVGLLTAPDGRTYAVAVMLRH +TRQPVPARLAFMQSVTRTVAEHw +>[subseq from] Beta-lactamase n=1 Tax=Legionella sainthelensi TaxID=28087 RepID=A0A3S4HK61_9GAMM +--ELSQRINAIEKNSRTVMGITAIHIEKNKVI-SHNSNQRFFMASTVKLPIALAFLHRVD +ENKDSLDRVIKMDTKNSVPGSGSLHHLFEKKMSLKQVLIHMMRNSDNSASDTILKVTNGP +KYVASRMSALGFKNIFVNRSILEMFLRFQNDTRDTTTSDDMAKLLVKLYKKQALSESNTK +LLIDIMEKCRTGRSRIKGLLPAHVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS +QSASDYPRSRAIALASRAIYDHf +>[subseq from] Beta-lactamase n=1 Tax=Microcoleus vaginatus FGP-2 TaxID=756067 RepID=F5UQ40_9CYAN +-----PQIESAIEQYSLSAGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFYQDVD +AGKVSLDETLVMKSDLVASGSGTMQDRPNGTFSIRETVDKMITISDNTATNMIIERLGGI +AKLNERFRSWGLTDTRIRNWLGDFQGT------NTTSSVDMVKLLAMLSRDKLVSESSRE +QALELLRNTTT-RTLLPSGLGPGAVIADKTGDIGF-VVGDAGIIDMPNGKRYLAAIFVKR +PYND-PIVRDFVRRISRIVYNY- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000FF868FE +------------------------------------------------------------ +-----------------------------------ELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Serine hydrolase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A291N1Y8_SPHYA +--HLLAEFDRFAALSDGTVGVAVQDLQTGEVQ-SRNGDTLFPMASAYKVAVAGRILSLVD +AGSLRLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP +KAVSDFVAGLGIHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLVAYESGKALKPESTQ +LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK +DSRGHVSRDQIMAQAARAAYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Actinomadura sp. CNU-125 TaxID=1904961 RepID=A0A1Q9SHU1_9ACTN +-----DELARRASASGGRLGLAVHDLGTGERA-EVDAGRVFTAASVIKLPIMMTLLSGTE +AGTWSLDDRLPLAPSRRVGGAGVAAELADVPLSVRDLLTLMIIVSDNMATNLLIDLL-GM +DAVTSWCARHGMPRTVLARSMMDADAR-ARGHENRTTPADTAALLTGLARGDLLGERATA +HALEVLTRQQT-ADRLPRHLPGGVRLAHKTGELD-GVRHDAGIVLADGRAPIVIVVLTEG +FA-DEDHAADLVAEAGRVVYT-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2W6WXL8_9SPHN +--HLLAEFDRFAALSDGTVGVAVQDLQTGEIQ-SRNGDTLFPMASAYKVAVAGRILSLVD +AGSLRLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP +KAVSDFVAGLGIHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLVAYESGKALKPESTQ +LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK +DSRGHVSRDQIMAQAARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Akkermansia glycaniphila TaxID=1679444 RepID=A0A1C7PCU8_9BACT +------GLEKAVRLSDGKVGFFVLDLDSGASA-GWGDEGMYPMMSVFKFPLALSVLSRVD +EGKLDLDAKYRVAGKDLDPWSPMREKFPQGGFTLRELLRYSVAESDNNACDFLFGLIGGP +AAAQADLKKWGVEDISIRVLEGVMQDDWNAIYLNAARPSAMAGLLKLFADGKILREATNR +ELWEMMAGCKTGTDRLVQGMPAGAVLAHKTGSSGVGAFNDVGIAVLPDGRRLAICAFVSD +SRRPVKECAAVIASLARWACSEw +>[subseq from] Uncharacterized protein n=3 Tax=unclassified Cyanobacteria (miscellaneous) TaxID=1983111 RepID=A0A3B8JK67_9CYAN +---LKAKIQTLVAQYQLQAGVFLLDLETRAYL-DLNSDSTFASASTIKLPILIALFQDVE +AGKVRLDESLTLKSEMRVGGSGDLQKKPGTQYILLEVAKKMIAISDNTATNMLIERLGGI +EALDQRFHSWGLTTTVLRNVLPDLEGT------NTTSPKELANLMLMVNQGRLVSERSRD +RIIDIMQQTQT-NTLLPKGLGVGATIAHKTGTLGS-LLADIGMVDLLTGKRYIVSVMVKR +PHND-AAAEELIRQISRTTYDYf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KJI0_9BACT +--PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD +KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT +SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK +FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD +SMEDDKTNAAIIAQISKAVYDY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Odoribacter splanchnicus TaxID=28118 RepID=UPI000D90A6BC +--PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD +KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT +SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK +FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD +SMEDDKTNAAIIAQISKAVYDY- +>[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=A0A127SZ44_9BACT +--PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD +KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT +SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK +FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD +SMEDDKTNAAIIAQISKAVYDY- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SZN7_9BACT +--PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD +KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT +SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK +FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD +SMEDDKTNAAIIAQISKAVYDY- +>[subseq from] Beta-lactamase n=1 Tax=Odoribacter splanchnicus TaxID=28118 RepID=A0A412WI85_9BACT +--PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD +KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT +SALQKYVRRQGIKQMKITATEDRMHKS-GNPYLNHTRPSSAVRLLEKFIQQELLSPVYQK +FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD +SMEDDKTNAAIIAQISKAVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Moorea producens PAL-8-15-08-1 TaxID=1458985 RepID=A0A1D8TW64_9CYAN +---LQKQIQTLVKQHQLQPGIFIHDLDTGAFL-ESNSRLIFPAASTIKLPILIAFFQDVD +AGKVFLDEYITMKPEMIAGGSGNMQQKPGKQYKALEVANKMITISDNTATNMLIERLGGI +EVLNQRFRSWGLKKTVLRNPLPDLPGT------NTTSPRELASLIFHLEQGKWISPQSRT +DLINIMIQTKT-NTLLPQGLGNGATIAHKTGTLGR-LLADVGLVKMPNGKRYIISVMVKR +PFND-ASAEKLIRTISRQAYDYf +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X220_9BACT +--ELTKRLATLAKSIGDDVGVTVIHVETGRTI-TVDGAKKLQLYSVFKVPLAIAVLKAVE +EKKISLEQKLHVTPSDVAPGSQINTDLWRRPKNVAELLEFSIVRSDNTSSDKLMQLIGGP +AVVTERMRALGYSNIDIVTTVRDFAA--KGENPNVGTPADLARLLTQLQKGELLQPANAS +LLLGYMERARTGERRLRANLPAGTQVAEKTGSGT-AATNDIGLITLPDGGHLAIAVLING +TKSKTDAQEKLIAETARAAYDAf +>[subseq from] Beta-lactamase n=2 Tax=unclassified Rhodanobacter TaxID=2621553 RepID=A0A1E4Q6S9_9GAMM +--VLQGKLEALARRAPGVLGITVLDPQSGERW-RVNAERAYPMMSVFKAPVAAAVLARID +SGTLTMHETVTLTRADLVAGSPSIGAHFHGEFTVRQLLTAAVSESDNTAVDALLKLV-PP +QDVTAFLRAHGITGMRVDMGEAGVGRAYLADPRNRSTPDAAADLLRQLQRGVLLSPSSTH +ALLVLLQAQTQ-PSRLRQGLPHDVQLADKCGTSYTAAYNDIGILTWPDGRSVIVAAFLTA +STASKAEREALFADLARTVANTw +>[subseq from] Beta-lactamase n=1 Tax=Listeria riparia FSL S10-1204 TaxID=1265816 RepID=W7D7U0_9LIST +------------------------------------------------------------ +--EQQLEKRVFFKKEDLVDYSPVTEKHVESGMTIKEIIHAAVAYSDNTAGNLLFNALNGP +KGFQDELRKIKDETTNADRYETELNVAVPGDPRDTSTPEAFSKNLAFLTRQGNLQPKQLD +YFKQTLIENTTGGKLIRAGIPKDYIVGDKTGAGSYGTRNDIAVIYSDDREPLVWVIFSKK +DKEDATYDDQLIADASKVLSQYf +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia ursingii TaxID=1756150 RepID=UPI00099950FE +-sQLKKTLESIISGKKATVGISVMSPDEKEMT-GINANQMLPMLSTVKFPLALAVLYEVE +KGKLSMNQKLFIKKEELLDWSPFKEKYPAGNITLEEALKWTVSYSDNNLTDILIRLIGGP +ETVQEFMDS---NSFIIKNNEEGMHKDWDSQFINKITPNFAVLLLQEFSNGKILNKTNTQ +WLYNAMLNNVSGKKRLKGNLPTGVKVAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] Serine hydrolase n=1 Tax=Blastomonas fulva TaxID=1550728 RepID=A0A222WXM0_9SPHN +--GLRDELAQLWRSFPGKTGIAVRRIDGDWVV-GHRGGELFPQQSVSKLWVTMAVLEKVD +RGELSLDTEVTITPEDLTLHQPLAARVAREGETVRTLINEALTASDNSANDALLRTAGGP +GVVNDFLRRKGLSSIRFGPGERLLQSAYVADPIDGASPEGIVNALARLARGELLSQNSTR +LMLDTLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLGE +TTAGIPARMQLMQAVSRAV---- +>[subseq from] Beta-lactamase n=1 Tax=Cylindrospermum sp. NIES-4074 TaxID=2005457 RepID=A0A1Z4QIU2_9NOST +---LKTAVQNLATANNLTPGVFVVDLDTGAYV-DVNSTASFPAASTIKVPILIAFFQDVD +GGKIRLDEMLTMKQEMMAGGSGNLQYKPAGTYTALEVATKMITISDNTATNILIARLGGM +EVLNERFRTWGLASTVIRNQLPDLPGT------NTTSPRELGNLMAMVNQGNFLSMRSRD +LMLDIMRRTER-DNLLPSGLGTGARIYHKTGDIGT-MLADAGLVDIPTGKRYIASVMVKR +PNND-PRAEKLISSISRAAYQQ- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas panacis TaxID=1560345 RepID=UPI0009F65F9E +--ALARSINAVARSFDGRVGVAVRSIDKGWTV-ESNGDVRLPQQSVSKLWVAMTVLDLRD +SGRLTLDDPITLTRNDLTLHQPVASLLKNGETTVGELLRRALTMSDNTCNDRLLRYVGGP +SAVRDFIARKGLGNIRFGPGERLLQSRYVADPPDGAAPRAIADALARLKKDELLSPNSTA +FLISTMESSKTGKQRMRGAVPVGWSFGHKTGTGQTAGYNDVGLLMAPDGRAYAIAVMIGD +TPRTIPQRQELMQSVVQAVVA-- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingopyxis indica TaxID=436663 RepID=A0A239GEV3_9SPHN +---LEARIHSLWQSFPGKTGIAVQRIDGDWAF-AERGDDLFPQQSVSKLWVTLTVLDAID +RGELSFDQKVRIGPEDLTLHQPLAARVRSEGMTIRDLIETAITHSDNTANDSLLRTVGGP +KAVNGFIARKDLGAIRFGPGERLLQSSYLADPPDGASPSAIARALTRLARGELLSPESTK +YVLGVMSRTRSGPKRLKAGLPAGWEFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGT +TTSSVPARMALMQAVSGAVADY- +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5U895_9BACT +--DVADRIAAIEGRIGCRIGVAALDTGNRKRL-DYRADERFPMCSTFKFLAAAAVLKRVD +EKQEKLERFVPYDAKEILEYAPVTKEHLKDGMMLGALCEAAIEQSDNTAGNLLLDAIGGP +AGLTNFARDLGDRITRLDRKEPDLNSAIPGDERDTTTPGSMLGEMTRLLTGDVLSQ---- +------------------------------------------------------------ +----------------------- +>[subseq from] Putative beta-lactamase class A n=1 Tax=Sphingobium sp. (strain NBRC 103272 / SYK-6) TaxID=627192 RepID=G2IPD5_SPHSK +--ALVATIRELGRQFPGKVGIAVYNVEAGWTV-EHNGDQLFPQQSVSKLWVAMTLMDAVD +RGKLSLDRAVTIKQSDLTLHQPIAAMVKGEQTTLRNLLDRAMQQSDNTANDSILRTVGGP +EAVRGYLARFGPDSIRFGPGERLLQSAYLSNPPDGASPVGIARALGKLRKGEMLSPHSTR +ELLAIMTDAKTGPQRVKAGVPAGWSYAHKTGTGQSTGYNDVGIMTAPDGTAYAIAVMIGE +TSAPIPKRWELMQSVSRAV---- +>[subseq from] class A beta-lactamase n=1 Tax=Legionella longbeachae TaxID=450 RepID=UPI0012461D96 +--ELSRRISAIEKNSRTVMGITAIHIEKNKII-SHNSNQRFFMASTVKLPIALAFLHRVD +ENKESLDRVIKMDTKNSVPGSGSLHHIFEKKMSLKQVLIHMMRNSDNSASDTILKVTNGP +KYVASRMSALGFKNIFVNRSILEMFLRFQNDTRDTTTSEDMAKLLVKLYKKQALSESNTK +LLIDIMEKCRTGRSRIKGLLPAHVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS +QSASDYPRSRAIALASRAIYDHf +>[subseq from] Beta-lactamase n=1 Tax=Legionella longbeachae serogroup 1 (strain NSW150) TaxID=661367 RepID=D3HM63_LEGLN +--ELSRRISAIEKNSRTVMGITAIHIEKNKII-SHNSNQRFFMASTVKLPIALAFLHRVD +ENKESLDRVIKMDTKNSVPGSGSLHHIFEKKMSLKQVLIHMMRNSDNSASDTILKVTNGP +KYVASRMSALGFKNIFVNRSILEMFLRFQNDTRDTTTSEDMAKLLVKLYKKQALSESNTK +LLIDIMEKCRTGRSRIKGLLPAHVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS +QSASDYPRSRAIALASRAIYDHf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. SYSUP0001 TaxID=2303576 RepID=UPI0013C35EE9 +---LEQRIDQLGQSFDGTVGIAVRSVGDGWRT-GWRETELCPQQSVSKFWVALAAMEAVD +RGQVSLGDRVTLRRDDLTLHQPIASRILGGGVTLEELLVEALTKSDNTANDKLMRSIGGP +TAVRSFISRHQLGAIRFYDGERALQSRYLADPYDGATAGAIVDALARLKRGELLSPASTA +RLLTIMGNTKTGANRLKGGLKPGWSLSHKTGTGQQAGYNDIGVLTAPDGASYAVAVMIKR +TATPLEVRMTLMNDVVRAVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides clarus TaxID=626929 RepID=A0A1Y3YYH5_9BACE +-qTLESKIGDFLKGKKAMVGVAVL-TDRNKIL-LHNNKMNYPLLSVFKFHVALAVLDKMN +KQGTPLDHIVHVKASQLQPYSPLRQKYPNQDISLGELLRYSISLSDNNACDILIEYAGGI +GHTHQYINKLGICDFNLSETEDSMHRNPSKTYLNWSTPAEMVRLLEIADKKELFDPIYKD +FLWNTMIATSTGSNKLKGLLPSNAIVGHKTGSSDRNADNDAGVVIMPDGKKYYIAVFVMN +SRETDDENAAIIARISRMVYDEy +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000B35F02B +---LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=A0A2L0NGC2_9STAP +-----------------------------RILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDXRDTTMPVAMATTLRKLLTGELLT----- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Propionibacteriaceae TaxID=31957 RepID=A0A4R6LLY6_9ACTN +----AALIADLERRHDVRIGLSAAALTRGRRL-DHRADERFLMLSVFKAIAAAAVLDGIT +PDPKVLDRPVFLPPEAICEPAWFAEQIAARRPSVTEVCRAAIQLSDSTAANALMSLTGGP +DSITRFARDNGDPVTQLTEWEPELNT--PDGDRNTTSPRAIGALFAAMIVGRALRTPARR +RLTDWMLGNQTSDQRFRAGLPAGWTLADKTGSGIDATANDVGIAFDPAGNAYQLAVLTSS +PRPDTERVNEIFAILAREAL--- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides dorei TaxID=357276 RepID=A0A4R4GUB5_9BACE +-kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKRYFKPYSPLRDKYPQGNLPISELLAYTMQLSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITTTEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDSMKNEYTN +FLKHIMIECETGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGNRYVVAVFVKD +SKENMETNTKIISDISAAIYRY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=UPI00101CF359 +-qTLESKIGDFLKGKKAMVGVAVM-TDRNKIL-LHNNKMNYPLLSVFKFHVALAVLDKMN +KQGTPLDHIVHVKASQLQPYSPLRQKYPNQDISLGELLRYSISLSDNNACDILIEYAGGI +GHTHQYINKLGICDFNLSETEDSMHRNPSKTYLNWSTPAEMVRLLEIADKKELFDPIYKD +FLWNTMIATSTGSNKLKGLLPSNAIVGHKTGSSDRNADNDAGVVIMPDGKKYYIAVFVMN +SRETDDENAAIIARISRMVYDEy +>[subseq from] class A beta-lactamase n=1 Tax=Propionibacteriaceae bacterium NML 061049 TaxID=2016501 RepID=UPI000B9767DD +----AALIADLERRHDVRIGLSAAALTRGRRL-DHRADERFLMLSVFKAIAAAAVLDGIT +PDPKVLDRPVFLPPEAICEPAWFAEQIAARRPSVAEVCRAAIQLSDSTAANALMSLTGGP +DSITRFARDNGDPVTQLTEWEPELNT--PDGDRNTTSPRAIGALFAAMIVGRALRTPARR +RLTDWMLGNQTSDQRFRAGLPAGWTLADKTGSGIDATANDVGIAFDPAGNAYQLAVLTSS +PRPDTERVNEIFAILAR------ +>[subseq from] serine hydrolase n=1 Tax=Nostoc sp. NIES-3756 TaxID=1751286 RepID=UPI0009E8DEE1 +--SLKNTVQELAAANNLTPGVFLVDLETGGYV-DVNGSSSSPAASTIKIPILVAFFQDVD +AGKIRLDEMLTMQQEMVAGGSGNFQKPVGTKFAALEVATKMITISDNTATNMLIARLGGM +EALNERFRSWGLTTTAIRNPLPDLQGT------NTTSPKELGNIMTLVSQGNLVSMRSRD +QILDIMRQTER-DNLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYIVAVMVQR +PNND-PRAEKFISSVSRAAYQQf +>[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia bruuniana TaxID=1756149 RepID=A0A5E8CYZ6_9FLAO +---LKKTLESIISGKKATVGISVIGPDTKEVT-GINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMAQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHD +TYESFEASEKIISDIGRATYDYy +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides intestinalis TaxID=329854 RepID=A0A139KM17_9BACE +-qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI +DQVNEYVKSLGIKDCNLVATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD +FLQAIMQETSTGKDKLKGQLPTDVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQETDTGNAAIIASISKIVYDT- +>[subseq from] Beta-lactamase 3 n=1 Tax=Bacillus cereus HuA4-10 TaxID=1053206 RepID=J8A8S9_BACCE +------------------------------------------------------------ +-------------------------------MFLKELADASVRYSDSTAHNLILKQLGGP +SEFEKILREMGDTVTTSERFEPELNEVHPEETHDTSTPEAIAKTLQSFTLGTALPIEKRE +LLVDWMKKNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH +DKEDATYDDKLIAEATKIVLN-- +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI0008404574 +---LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDESEKIISDIGRATYDYy +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. IP1 TaxID=2021637 RepID=A0A2G1LNY5_9SPHN +--HLLAEFDRFAALSDGTVGVAVQDLQTGEIQ-SRNGDTLFPMASAYKVAVAGRILSLVD +AGSLKLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP +KAVSDFVAGLGVHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLVAYESGKALKPESTQ +LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK +DSRGHVSRDQIMAQAARAAYDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=UPI00104CE4D0 +--SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG +KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV +DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD +FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAAFVKD +SEENNQENSKIIADISRIVYEY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A430BI38_SPHYA +--HLLAEFDRFAALSDGTVGVAVQDLQTGEVQ-SRNGDTLFPMASAYKVAVAGRILSLVD +AGSLKLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP +KAVSDFVAGLGIHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLIAYESGKALKPESTQ +LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK +DSRGHVSRDQIMAQAARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium herbicidovorans (strain ATCC 700291 / DSM 11019 / NBRC 16415 / MH) TaxID=1219045 RepID=A0A086PB77_SPHHM +---LLGEFARFATLSDGTVGIAVRDLHNGETL-QYNGDTLFPMASTYKVAVAGKILSLAD +AGTLRLDEKLP---------------RLGTPLSVNTLLDLMLTRSDNEATDTLVARAGGP +QAVHGWLKSIGIRGQRVDSNTAQLLAAFAADPRDTSTPRAMNDLLSAIHHGKALKGPSAA +MLLGIMSRCRTGKARLVGMRPPGTPVAHKTGTLN-GLGNDTGIITLPDGRRIAISVFVMK +DHRGHAARDRIMAEVARAAYDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=UPI00101D9668 +-kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AVNNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKRYFKPYSPLRDKYPQGNLPISELLAYTMQLSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITTTEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDSMKNEYTN +FLKHIMIECETGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGNRYVVAVFVKD +SKENMETNTKIISDISAAIYRY- +>[subseq from] Serine hydrolase n=1 Tax=Symploca sp. SIO2E9 TaxID=2607812 RepID=A0A6B3MD01_9CYAN +--ELKAQMQAIVAQNKLQPGVFLLDLDTGAYL-DWDSRSIFAAASTIKVPILVAFFQALD +AGKVRLDETLIMESEMIASGSGDMQQQPGKHYTALEVVTKMIAISDNTASNMIIARLGGA +EVLNQQFRSWGLATTAISNLLPDLEGT------NTTSPREIARLMSMVNQGQLLSLRSRD +RLLSIMQRTQN-DSLLPQGLGNGATIAHKTGNIGS-VLADVGIVDMPTGKRYIIAVMVKR +PH-DDPSAQKLIRDISRTAYNYf +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter halimionae TaxID=1926630 RepID=UPI00135DE8B1 +-kNLAARIEAVADGSRGRIGVAAMDLSTGQTL-GVLDRQFFPMASTSKIAVAATFMEGVE +QGRWSLTSEFPLLWPLRSKSSRAAPVREGKHLPAIELIELMLTRSSNPSTDALLRVVGGP +EAVNDWMRRNGIEDFSLDRDIATLVRATKIDTRDAATPRAMLQLLAGLHNGDFLSAKSRA +VILSAMSRCRTGKRRIPALMPSGAKVAHKTGSLNN-TSSDVGFITAPSGRTYAVAIYVTG +QG-SRSNREARIARIARELLDGy +>[subseq from] serine hydrolase n=1 Tax=Nostoc sp. PA-18-2419 TaxID=2575443 RepID=UPI001107C73A +---LKNAVQNLTSNLNLKPGVFLVDLDTGNYV-DIDASTSFPAASTIKLPILIAFFQDVD +AGKIRLDEMLTMQQDAIAGGSGNLQKSAGTQYAALEVVTKMITISDNTATNMLIARLGGI +DALNQRFRSWGLTTTVIRNQLPDLEGT------NTTSPKELGNLMAIVSQGNLVSVPSRD +LMLDILRRTQK-DTLLPSGLGTGARVYHKTGDIGT-MLADAGLIVVPTGKRYVAAVMVQR +PNND-PRAEKLISSISRVAYQEf +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=UPI000CCC607D +----QQALEEVLTDSPGVFGVAAAHLETGKSA-GNLDDQLFQLASAFKIPIMVTLMREVE +AGKLRLDQRVTLKRDERVPGSGVLQELDAGALTVKDLATLMTIVSDNYATDLVLELIGGI +EQVTAHMHELGLKDIHLRHTCWQLLNSQPTLENNVATPADLNRLLIMIAQKEILTPASCD +LMLDILRRQQY-NSRLPFLLPEGTKVAHKTGTVN-AVVNDAGIIYLPNGKGIAITVLSRG +IT-EKSAAELTIARVARAIYDQ- +>[subseq from] Penicillin-binding protein n=2 Tax=Calothrix sp. 336/3 TaxID=1337936 RepID=A0A0T7BRF9_9CYAN +---LKTAVQNLAASNNLTPGVFLADLDSGSYV-DLNGGAAFPAASTIKIPILVAFFQDVD +QGKIRLDETLTMEKEMVATGSGDMQKAVGSKFSALDVATKMMVISDNTATNMLIARMGGV +ETLNQRFRSWGLNTTNIRNILPDLEGT------NTTSPKELGNLLGMVSKGNLLSMTSRD +RLLYIMRRTVR-DNLLPAGLGQGAIIAHKTGDIGN-MLGDAGLVDLPTGKRYIAAVMVQR +PRND-TSAEKMINSVSRVAYQQf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. ABOLF TaxID=1985879 RepID=A0A430DQE5_9SPHN +--DLTRAITTLLANFNGTAAAAVTSIDSGWTV-AYNGSRPMPQQSVSKLWVAMTALDLLD +QGKLTLDDPVVVRREDLTLHQPIASLVKGDGTTVRELMRRALTMSDNTANDRLLTYVGGP +NAVRAFLARRGIQNIRFGPGERLLQSAYVANPPDGAGATAIAEALMRLKQGKLLSPNSTR +YLLDTMAASRTGRARLHAALPPGWTLAHKTGTGQNAGFNDVGILTAPDGRSYAVAVLIGD +TRAPMRDRQQLIQQVVHALV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. FJAT-27238 TaxID=1679167 RepID=A0A0K9MJK6_9BACI +---WQQAVEDVLKEAPGIFGIAAMHLETGETV-GHLDEELFQLASAFKIPIMVTLMREVE +AGRIRLDQRVTLKWEDRVPGSGILQELEAGALTVKDLATLMTIVSDNYATDQILELIGGI +DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE +LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEEKGMIAITALSR +GVTDTEAAEVTIARVAKAIYE-- +>[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter aquimaris TaxID=255984 RepID=UPI00135E9EE1 +--MLEARLQQIGEGFAGEVGIAAVEVTSGATM-AYNGARPFPQQSVSKLWVSLTALDLVD +EGALDLSEPVAIRREDLTVYQPIRDIVRTRGTDYRDLMERALTQSDNTANDRILRRVGGT +QAVEAFMRRKGIEGVQFGTDERSKQSDYLDDPIDGASASGMAQALARLARGELLSPRSTE +LILSTLENTKSGPKRLKGGVPSGWSIAHKTGTGQHSGYNDVGVLTAPDGTKYALAVMIAR +TRTSYAARFEMMQSVTRAVVEY- +>[subseq from] PenP, beta-lactamase class A n=2 Tax=Nostoc sphaeroides TaxID=446679 RepID=A0A5P8VZW9_9NOSO +--SLKNAVQNLAAANSLTPGVFIVDLDTGNYV-DVNGSINFPAASTIKIPILIAFFQDVD +AGKIRLDEMLTMQQDMVAGGSGDMQKSAGTQYAALEVATKMVTISDNTATNMLISRLGGM +EALNERFRNWGLTNTIIRNQLPDLQGT------NTTTPKELGNLMAIVSQGSLVSMPSRD +LMLDILRRTQR-NTLLPSGLGTGARVYHKTGDIGT-MLADAGLIGVPTGKRYVATVMVQR +PNND-PRAEKLISSISRAAYEEf +>[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter sp. HT-58-2 TaxID=2023229 RepID=A0A2L0GGQ4_9SPHN +--SFEQRIAELANPAMGRIGVAAIDLATGEEV-MVLGDQLFPMASTSKVAVAATYLELVE +KGRYSLTSEFPLLLPVRSAFSSARAPVREGQMQAIDLIEIMITRSSNPATDALLAAVGGP +AAVNDWMRRQGINQFSINRDIATLVRATHIDSRDAATPRAMAQLLAGLYRGEYLSDQSRQ +VLLGAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDVGLIECPDGRVIAVAIYVTG +QG-TKLAREERIAAIARALYDGf +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A078QQC5_BACVU +-kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD +FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD +SKENMETNAKIISDISAAVYRY- +>[subseq from] Uncharacterized protein n=1 Tax=Trichormus variabilis NIES-23 TaxID=1973479 RepID=A0A1Z4KMI8_ANAVA +-----NVVQQLATATNLSPGVFLVDLDTGGYV-DINAANALPAASTIKIPILVAFFQDVD +AGKIRLDELLTMKQEMVAGGSGNFQYKPAGTYPALEVATKMITISDNTATNMLITRLGGM +EALNERFRSWGLTNTVIRNILPDLPGT------NTTSPKELGNIMTMVSQGNLVSMRSRD +QILDIMRQTER-DNLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYVVAVMVQR +PNND-PRAEKLISSISRAAYQQf +>[subseq from] Alr4543 protein n=1 Tax=Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) TaxID=103690 RepID=Q8YNM1_NOSS1 +-----NVVQQLATATNLSPGVFLVDLDTGGYV-DINAANALPAASTIKIPILVAFFQDVD +AGKIRLDELLTMKQEMVAGGSGNFQYKPAGTYPALEVATKMITISDNTATNMLITRLGGM +EALNERFRSWGLTNTVIRNILPDLPGT------NTTSPKELGNIMTMVSQGNLVSMRSRD +QILDIMRQTER-DNLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYVVAVMVQR +PNND-PRAEKLISSISRAAYQQf +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. GW247-27LB TaxID=2012632 RepID=A0A270BE67_9SPHN +---LEERIFGLWRAFPGKTGIAVQRIDGEWTL-QQRGDDLFPQQSVSKLWVTLTVLDAVD +RGALTLDRKVSITPADLTLHQPLAARVRSEGMSVRDLIETAITHSDNTANDSLLRTVGGP +DAVRRFIAAKDLGSIRFGPGERLLQSNYLANPVDGASPSAIARALTRLARGTLLSPESTD +YVLGVMSRTHSGPKRLKAGLPAGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGS +TTASIPQRMALMQAVSGAVAE-- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Cyanobacteria (miscellaneous) TaxID=1983111 RepID=A0A2T1FKV4_9CYAN +------QIESAIDQYSLSAGMFFLDLDTGDYL-DIKGDRVFPAASTIKLPILIAFYQDVD +AGKISLDETLVMKSDLVASGSGTMQDEPDNTFSIRETVDKMITISDNTATNMIIERLGGI +AKLNERFRSWGLTDTRIRNWLGDFQGT------NTTSSVDMVKLLAMLSRDKLVSESSRE +QALELLRRTTT-RTLLPSGLGAGAVIADKTGDIGF-VVGDAGIIDMPNGKRYLAAIFVKR +PYND-PIVRDFVRRISRIVYNY- +>[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium hankyongense TaxID=1813876 RepID=A0A328AXD3_9CAUL +--ELQARLDALAAAYHEPVGIAVVDVKDGWTA-AVDGDSAYPQQSVSKLWVAMSVLDAVD +HGGLALDQAVVVTRDDRSVYQPLGERVGEKGTTLHDLLRRALTESDNAANDKLMREVGGA +GAVTDALAEKGLSHIAVGAYERELQAAYLADPPDGASPSAVAHALAALERGDLLSKASSE +TMLTLMGEARTGRMRLRGGLPPGWKIAHKTGTGPSVGINDVGLLTAPDGRVYAVAVMMRQ +TRKPVPQRLALMQAVTRAVADSw +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=A0A0K9YKP9_9BACL +----QQALEDVLTDSPGVFGVAATHLETGKTA-GNLDDQLFQLASAFKIPIMVTLMREVE +AGNIRLDQRVTLKQDERVPGSGVLQELDAGALTVKDLATLMTIVSDNYATDLVLELVGGI +EQVTAHMHELGLKNVHLRHTCWQLLNSKPTLENNVATPADLNRLLIMIAQKEILTPASCD +LMLDILRRQQY-NSRLPFLLPEGTKVAHKTGTVN-AVVNDAGIIYLPNGGTIAITVLSRG +VT-EKSAAELTIARVARAIYDQ- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=R6FI74_9BACT +--PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD +KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT +SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK +FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD +SMEDDKTNAAIIAKISKAVYDY- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SF68_9BACT +--PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD +KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT +SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK +FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD +SMEDDKTNAAIIAKISKAVYDY- +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Nostoc sp. NIES-2111 TaxID=1973475 RepID=A0A1Z4IGB9_9NOSO +--SLKNTVQELASANNLTPGVFLVDLETGGYV-DVNGSSSSPAASTIKIPILVAFFQDVD +AGKIRLDEMLTMQQEMVAGGSGNFQKPVGTKFAALEVATKMITISDNTATNMLIARLGGM +EALNERFRSWGLTTTAIRNPLPDLQGT------NTTSPKELGNIMTLVSQGNLVSMRSRD +QILDIMRQTER-DHLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYIVAVMVQR +PNND-PRAEKFISSVSRAAYQQf +>[subseq from] serine hydrolase n=1 Tax=Nostocaceae TaxID=1162 RepID=UPI0009FDE5D9 +-----NVVQQLATATNLSPGVFLVDLDTGGYV-DINAANALPAASTIKIPILVAFFQDVD +AGKIRLDELLTMKQEMVAGGSGNFQYKPAGTYPALEVATKMITISDNTATNMLITRLGGM +EALNERFRSWGLTNTVIRNILPDLPGT------NTTSPKELGNIMTMVSQGNLVSMRSRD +QILDIMRQTER-DNLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYVVAVMVQR +PNND-PRAEKLISSISRAAYQQf +>[subseq from] class A beta-lactamase n=1 Tax=Fischerella sp. PCC 9605 TaxID=1173024 RepID=UPI00047C0C34 +---------------NLTPGVFVVDLDNGGYV-DINASSSFPAASTIKIPILVAFFQDVD +AGKIRLDEMLTMQKEMVAGGSGDMQYKPAGSFKALEVATKMMTISDNTATNMLITRMGGI +EALNQRFRSWGLTTTVIRNQLPDLQGT------NTTSPKELGNLMGMVSQGNLVSMISRD +RILDIMRNTVR-NTLLPSGLGQGATIAHKTGDIGT-MLADAGLVDLPTNKRYVVAVMVKR +PNND-PNARKLISSISRAAYQQf +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00136B07B4 +---LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEVLKWTVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRTAYDYy +>[subseq from] Beta-lactamase n=1 Tax=Legionella sainthelensi TaxID=28087 RepID=A0A0W0YJM8_9GAMM +--ELSQRIDAIEKNSRTVMGITAIHIEKNKVI-SHNSNQRFFMASTVKLPIALAFLHRVD +ENKDSLDRVIKMDTKNSVPGSGSLHHLFEKKMSLKQVLIHMMRNSDNSASDTILKVTNGP +KYVASRMSALGFKNIFVNRSILEMFLRFQNDTRDTTTSDDMAKLLVKLYKKQALSESNTK +LLIDIMEKCRTGRSRIKGLLPPHVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS +QSASDYPRSRAIALASRAIYDHf +>[subseq from] Serine hydrolase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A2D1R0W0_SPHYA +--HLLAEFDRFAALSDGTVGVAVQDLQTGEVQ-SRNGDTLFPMASAYKVAVAGRILSLVD +AGSLKLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP +KAVSDFVAGLGIHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLVAYESGKALKPDSTQ +LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK +DSRGHVSRDQIMAQAARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. EG6 TaxID=1874061 RepID=A0A2Z5UER5_9SPHN +---LAERINFLWRGFPGKTGIAVQRIDGEWAI-AERGGELFPQQSVSKLWVALTALDAVD +QGRVRLDQQVRIGPEDLTLYQPLAARVRAQGMTLRQLIETAITQSDNTANDSVLRTVGGP +GAVRAYMAKKDLGAIRFGPGERSLQSNYLANPIDGASPTAIASALTRLARGTLLSPESTE +YLLDVMSRTKSGPKRLKAGLPPGWKFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGT +TTSPIPARMALMQAVSSAVAE-- +>[subseq from] Serine hydrolase n=1 Tax=Paraburkholderia sp. 7MK8-2 TaxID=2419777 RepID=A0A494XNP1_9BURK +------------SATTGSFGIAVIDLGSGAVT-GVNLDRPYPMMSVFKAPLGVTVLDQVE +KGSIGLDQVVTLTRADLRNTSPIREHFVGDKFTVRQLLDYGISQSDNSAADALVRLVGGP +LVVTRFLQAHGVEGMRVEMDEGTVSHAYLADPRNRSTPRAAAAFLRKLWAGELLPPRETQ +ALLNLLYAQTT-PSRLRKGMPAGVRLADKCGTSETAAYNDIGIVTGPNGHTAIVAAFLTA +SQATQAEREAWFAELGRQV---- +>[subseq from] serine hydrolase n=1 Tax=Sphingopyxis sp. 2PD TaxID=2502196 RepID=UPI0010F7D21B +---LAERINFLWRGFPGKTGIAVQRIDGEWAI-AERGGELFPQQSVSKLWVALTALDAVD +QGRVRLDQQVRIGPEDLTLYQPLAARVRAQGMTLRQLIETAITQSDNTANDSVLRTVGGP +GAVRAYMAKKDLGAIRFGPGERSLQSNYLANPIDGASPTAIASALTRLARGTLLSPESTE +YLLDVMSRTKSGPKRLKAGLPPGWKFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGT +TTSPIPARMALMQAVSSAVAE-- +>[subseq from] Serine hydrolase n=1 Tax=Oscillatoriales cyanobacterium USR001 TaxID=1880991 RepID=A0A1C0VEZ7_9CYAN +---LKAEIDKLTAQYSLTPGVFIVDLDTGGYT-SVSSDASFAAASTIKVPILVAFFQAVD +EGKVHLDQMLTLRSEHIASGSGDLQDAPGKKLTALEVATKMIEISDNTATNMLIDLLGGS +EALNQTFQTWGLKVTAIRNSLPDLAGT------NTTSPRELVNLMAQVNQGSLISQKSRD +RLFHIMRQTQN-DSLLPRGLGEGAMIAHKTGNINS-LSADVGMVDMPNGKRYLVAVMVKY +GK-NQKTAEKLIRDISRTTYQY- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A412QCC1_BACVU +-kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD +FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD +SKENMETNAKIISDISAAVYQY- +>[subseq from] serine hydrolase n=1 Tax=Nostoc sp. NIES-2111 TaxID=1973475 RepID=UPI000BBC325F +--SLKNTVQELASANNLTPGVFLVDLETGGYV-DVNGSSSSPAASTIKIPILVAFFQDVD +AGKIRLDEMLTMQQEMVAGGSGNFQKPVGTKFAALEVATKMITISDNTATNMLIARLGGM +EALNERFRSWGLTTTAIRNPLPDLQGT------NTTSPKELGNIMTLVSQGNLVSMRSRD +QILDIMRQTER-DHLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYIVAVMVQR +PNND-PRAEKFISSVSRAAYQQf +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus panacihumi W25 TaxID=1408254 RepID=V6MDB2_9BACL +---WQQAIDEVLQEAKGEFGVAVTHLESGMTV-GHQADQLFQMASVFKIPIIVTLMRDVE +AGKIRLDQRIPLRYEERVPGSGVLQELDSGALTVKDLAMLMTIVSDNYATDMVINLV-GL +GNIEKHMRELGLESIYLPQTCWQLLNGAPTTENNVATPADLNRLLSMVAKKEILSAASCD +LILDILRRQQY-NSRLPLLLPPGTRVAHKTGTVN-GVVNDAGIIYLPEGGQIAISVLSRK +VEE-KQEAERTIAKVARAVYE-- +>[subseq from] Serine hydrolase n=1 Tax=Anabaena sp. 39858 TaxID=1710890 RepID=A0A1W5CPW4_9NOST +-------VQQLATANNLSPGVFLVDLDTGGYV-DINAANALPAASTIKIPILVAFFQDVD +AGKIRLDEVLTMQQEMVAGGSGNFQYKPAGTYPALEVATKMITVSDNTATNMLIARLGGI +EALNERFRSWGLTTTVIRNILPDLPGT------NTTSPKELGNIMTMVSQGNLVSMRSRD +QILDIMRQTER-DNLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYIVAVMVQR +PNND-PRAEKLISSISRAAYQQf +>[subseq from] Penicillin-binding protein, transpeptidase n=1 Tax=Trichormus variabilis (strain ATCC 29413 / PCC 7937) TaxID=240292 RepID=Q3MDA5_TRIV2 +-------VQQLATANNLSPGVFLVDLDTGGYV-DINAANALPAASTIKIPILVAFFQDVD +AGKIRLDEVLTMQQEMVAGGSGNFQYKPAGTYPALEVATKMITVSDNTATNMLIARLGGI +EALNERFRSWGLTTTVIRNILPDLPGT------NTTSPKELGNIMTMVSQGNLVSMRSRD +QILDIMRQTER-DNLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYIVAVMVQR +PNND-PRAEKLISSISRAAYQQf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Bacillus salarius TaxID=284579 RepID=A0A3R9NY76_9BACI +------------------------------------------------------------ +-----------------------------TGMTLLELSEAAVRSSDNTAGNFLFKKLGGP +DEFEQALRQIDDNVTQADRYEPDLNEFTPGDTRDTSTPIALANNLQAFAVGDLLSDEKRE +LFTDWLQGNATGDTLIRAGAPEGWNVGDKSGAGSYGTRNDIAVVWPPNREPIVIAIMSRH +DTEDAKYDDKLIAQVAEET---- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. B3058 49 TaxID=2183925 RepID=A0A2V5D1Z0_9SPHN +--AIQQRVASIVAGARGRVGVAAMDLDGGGQV-LINPDMPFPMASTAKVAVAATFLQMVE +QGKYRLDQQLPMMMPVPEPRNLVAMVRPGPVFTAQTLLEKSITRSDNHATDGLIAAVGGI +GAVNRFLMQTGISGQHLDHTMATLVRARAVDTGTSSTPRAMIALLSAIDRGGALSPQARA +VLLDTMTRTSTGRNRIRAGLPEGVLLAHKTGTLA-GVTDDVGIIRMPDGRHLALAIFVAG +PE-NHTAQAGMIARIASVVYEGf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. Leaf23 TaxID=1735689 RepID=UPI0006FF376F +--ALVAAINALGDGFQGRVGIAVRSIDDGWVV-GHAMDQRMPQQSVSKLWVALTTMNAID +EGRYALDTPVTITRSDLTLHQPVAYLMKDGATTVGDLLRRALTMSDNTANDKLLNLAGGP +VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLHHGMLLSPTSTR +WLLDTMSHTRTGRARIRAALPAGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD +TSRPVQERQQLIQTVVSSIV--- +>[subseq from] Serine hydrolase n=1 Tax=Phyllobacterium myrsinacearum TaxID=28101 RepID=A0A2S9JYA4_9RHIZ +--ALKHRLEALVQGKDGRVGICAQD-QKGTAV-CVRGEERFSLQSVVKLIAGAAVFDAAD +RGLTDLKEPIVVKPENLSLVQPLAKIVEREGTNADDLVRRAIVDSDSAAVDILIERLGGP +AKVDQFAEGKGILGIRVDRDERHLQTAYQKDPRDTATPRAMTEFLAALMNGKLLSTGSTQ +KLLAIMAETVTFPDRLRAGTGEGWAVAHKTGTSRNVATNDVGILTAPDGGKIAVAVFVAD +SRETPTQRSAIIAGAAQAVTEAy +>[subseq from] Beta-lactamase n=1 Tax=Oscillatoria nigro-viridis PCC 7112 TaxID=179408 RepID=K9VHM2_9CYAN +----KPQIESAIEQYSLSAGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFYQDVD +AGKVSLDETLVMKSDLVASGSGTMQDSPNGTFSIRETVDKMITISDNTATNMIIERLGGI +AKLNERFRSWGLTDTRIRNWLGDFQGT------NTTSSVDMVKLLAMLSRDKLVSESSRE +QALELLRHTTT-RTLLPSGLGPGAVIADKTGDIGF-VVGDAGIIDMPNGKRYLAAIFVKR +PYND-PIVREFVRRISRIVYNY- +>[subseq from] Beta-lactamase n=3 Tax=Bacteroides TaxID=816 RepID=R6S9U2_9BACE +---LKEQIQAIIHSCKAQVGVAFIW-NGQDTL-SINNDRPYPLMSVFKFHQALAVTHWLE +TRHLSLDTVLYITPEDLKPYSPLRDRYPQGNLSVRELLKYTLQQSDNNACDILFRLTGGP +QETDRYIRSLGCSHFSITATEDDMHVDLNRSYDNWTTPLEAARLLEIFLTRELFRPSDRQ +FIRQTLTECETGKDRLVKPIPSGAVIGHKTGTGDCNGINDIGFFLLPDGSRYSLAVFVKN +SEEDAPATAGVIAAISEAVWN-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides clarus TaxID=626929 RepID=F3PFE7_9BACE +-qTLESKIGDFLKGKKAMVGVAVL-TDRNKIL-LHNNKMNYPLLSVFKFHVALTVLDKMN +KQGTPLDHIVHVKASQLQPYSPLRQKYPNQDISLGELLRYSISLSDNNACDILIEYAGGI +GHIHQYINKLGVCDFNLSETEDSMHRNPSKTYLNWSTPAEMVRLLEIADKKELFDPIYKD +FLWNTMIATSTGSNKLKGLLPSNAIVGHKTGSSDRNADNDAGVVIMPDGKKYYIAVFVMN +SRETDDENAAIIARISRMVYDEy +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus sp. NRRL NRS-603 TaxID=2126351 RepID=A0A2P7WA14_9BACL +---WQQAVENVLKEAPGIFGIAAVHLETGETA-GHLDEELFQLASTFKIPIMVTLMREVE +AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELIGGI +DKVNEHMHELGLSQIHLPHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE +LMQDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVNT-VVNDAGIIYLPEGKGMIAITALSR +GVTDKEAAELTIARVAKAIYE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Anabaena sp. YBS01 TaxID=2490939 RepID=A0A5Q0GMB7_9NOST +-------VQQLATANNLSPGVFLVDLDTGGYV-DINAANALPAASTIKIPILVAFFQDVD +AGKIRLDEVLTMQQEMVAGGSGNFQYKPAGTYPALEVATKMITVSDNTATNMLIARLGGI +EALNERFRSWGLTTTVIRNILPDLPGT------NTTSPKELGNIMTMVSQGNLVSMRSRD +QILDIMRQTER-DNLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYIVAVMVQR +PNND-PRAEKLISSISRAAYQQf +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI000841404D +-nELKKRIENIITGKKVDVGVSIIGGNKNDKV-QINGNQLYPMLSTFKFPIALTVLHKVE +KGELKMSQKIFIKKEELLDWSPFLEKYPQGNITLEDALMWMMCYSDNNLTDILIRLIGGT +DTVQKF---IGTKDFIIKNDEEDMHKDWDSQFINKITPNRATQLLDKFYQGKILNGVNTK +WLYEAMLNNKTGLKRLKGKLAADIKVAHRSGTSFTGAINSYGIIELPKNKKIVITVFVHD +TYENFNDSEAIIADIAKTVYDYy +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. HDW15C TaxID=2714944 RepID=UPI0014073625 +--QLERRIDELGKGFAGRVGIAVESIDDGWTT-SWNGNELSPQQSVSKLWVSITALDAVD +KGKVRLTDAVSFDRSDLTLHQPIAARVLGGGTTLADLMFKAITTSDNTANDKLMRSVGGP +DAVRAMIRNKGLGAIRFYNGERSLQSRYIEDPYDGASANAIVHALSRLKRGELLSPSSTA +RLLNIMGNTKTGANRLKGGLRPGWSLSHKTGTGQQAGYNDIGILTAPDGSSYAVAVMIKK +TSVPLPTRMTLMNNVVRAVIAQ- +>[subseq from] Uncharacterized protein n=1 Tax=Tannerella sp. CAG:51 TaxID=1262979 RepID=R7DH77_9BACT +-rELKMRIASVLKEKRAIVGVAVLY-GDNRLF-EVNRG-DYPMMSVCKFPLALAVLDYLH +KNNLSLDTDIFIRESDLLPYSPLRDRHPQGNMSIRELLSYTVSLSDNNACDILFGYIGGT +KVVDDYIKRLGISGMSVVATEAVMHESFEKQYCNTATPSSAVLLLDKFLKEDLFRDEYGN +YLRKIMIETSTGNDKIKAGLPERVVMGHKTGSSDRNGDNDLAFVQLPDGQRYCIAVFIRD +SKEDDKTNAAIIASVSKVVYDY- +>[subseq from] class A beta-lactamase n=1 Tax=Legionella sp. km542 TaxID=2498108 RepID=UPI0013152018 +------------------------------------------------------------ +------SQRISYSKKDLTSWNPITEKHLSSGMTVEQLCAASISYSDNTAMNLLVKQMGGL +DQMTLFAHSLGNTSFRQDNWPEEAYSGGKGDLKDSSTPKDMANSLQKLSFTDVLAKPQRE +MLISWLKANTTGDLRIRAGLPKGWIVADKTGTGGYGTTNDLGIIWPPGCAPIVVAIYYSS +NDKQAKKRDDIVAIATRLLIT-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. K2R01-6 TaxID=2320861 RepID=A0A418W7J8_9SPHN +--ALQSAIRSLGASFDGSVGIAVRDVHTGWVV-DYNGRQPMPQQSVSKLWVAATLLEGVD +QGRISLSEMVMIRPSDLTLHQPIRQLVGKNGESVSGLLARAMTQSDNTANDSLLRRAGGP +AAVRSFLTSHGITDIRFGPGERLLQSRYLADPPDGATAIGMVDALAKLKRGELLSPRSTD +YLITTMRASRTGPKRLRGGISDGWLFGHKTGTGQSTGYNDVGLLTAPDGRTYAVAVMIGS +TRRSIPERMSLMQAVTRAVIS-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=unclassified Flavobacterium TaxID=196869 RepID=UPI00131E6380 +-dELRKEINQIISSKKADVGISILNLENGDTL-SFNGNKQYPMLSAFKFHVALTVLNKID +KGELSLNQKLFIKKHELLGWSPFKERYPNGDISLKEALEWTVSLSDNNLCDILIRLVGGV +KTVDNFICN---SDFIIKNDEEGMHKNWDAQFLNTITPNFSNQLLNRFLEKKLLTKKSTK +FLYETMVATSVGQNRIKGKLPSKTEVAHRTGSSFTGAINDIGIVKLPNGNRLIISVFVHN +TTEIFKDGEEIIANISKVTWNYy +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI000999A604 +-nELKKRIENIITGKKADVGVSIIGGNKNDKV-QINGNQLYPMLSTFKFPIALTVLHKVE +KGELKMSQKIFIKKEELLDWSPFLEKYPQGNITLEDALMWMMCYSDNNLTDILIRLIGGT +DTVQKF---IGTKDFIIKNDEEDMHKDWDSQFINKITPNRATQLLDKFYQGKILNGVNTK +WLYEAMLNNKTGLKRLKGKLAADIKVAHRSGTSFTGAINSYGIIELPKNKKIVITVFVYD +TYENFNDSEAIIADIAKTVYDYy +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas TaxID=13687 RepID=UPI000DEF7333 +---LAARIAELGRGFDGRVGIAVESVERGWRT-GWKTDELYPQQSVSKFMVALTVMDRID +HGALRLDQPVTLTRSDLTVHQPIRDVILANGTTLQDLLNRALTQSDNTANDKLMRLAGGP +EAVRGFIAERRLGEIRFADGERALQSRYIDDPYDGAAPFALVDTLARLKRGELLQPASTA +RLLTIMSDTVTGKNRLRGGLKAGWTLAHKTGTGQQAGYNDIGVLTAPDGRSYAVAVMMKR +TAVPLAVRMTLMNEVVRAIIA-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A085K7R1_SPHYA +--HLLAEFDRFAALSDGTVGVAVQDLQTGEVQ-SRNGDTLFPMASAYKVAVAGRILSLVD +AGSLKLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP +KAVSDFVAGLGIHGLRVDSDTAHLLYEFMLDPRDTATPLAMNQLLVAYESGKALKPDSTQ +LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK +DSRGHVSRDQIMAQAARAAYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingosinithalassobacter portus TaxID=2676234 RepID=UPI000D6E9D8B +----LSTITALESQFDGIVGIAVTSVDEGWSV-AANGERRMPQQSVSKLWVAMTVLDYRD +QGRLSLDDPYTVTKADLTVHQPVATLIGENGTTIRELLRRALTNSDNTCNDILLRYVGGP +DSVRDFISRKGLGAIRFGPGERLLQANYIADPPDGATATAIAQALARLKRGDLLSADSTS +WLLATMESSHTGRQRLRGAVPAGWSFGHKTGTGQTAGYNDVGILTAPDGKSYTIAVLIGD +TSRTIPQRQELMQAVVASVVA-- +>[subseq from] Uncharacterized protein n=1 Tax=Moorea bouillonii PNG TaxID=568701 RepID=A0A1U7N5F2_9CYAN +---LQKQIQTLVKQHQLQPGIFIHDLDTGAFL-ESNSRLIFPAASTIKLPILIAFFQDVD +AGKVFLDEYITMKPEMIAGGSGNMQQKPGKQYKALEVATKMITISDNTATNMLIERLGGI +EVLNQRFRSWGLKKTVLRNPLPDLPGT------NTTSPRELASLIFHLEQGKWISPQSRT +DLIDIMIQTKT-NTLLPQGLGNGATIAHKTGTLGR-LLADVGLVKMPNGKRYIISVMVKR +PFND-ASAEKLIRTISRQAYDY- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacteraceae bacterium CCH12-C2 TaxID=1768805 RepID=UPI0008300A61 +-nSFEQRIADLANPALGRIGVAAVDLTTGEQV-MVLGDQLFPMASTSKIAVAAAYLELVE +QGRYTLTSEFPLMMPVASASSPKAPVRPGQYMPAIDLIEIMITRSSNPATDALLAAVGGP +SVVSDWVRRQGINDFSINRDIATLVRARHIDTRDAATPRAMVRLLEGLYRGDFLSDQSRQ +VILSAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGIIETPDGRAIAVAIYVTG +QGG-KAAREERIAAIARALYDGf +>[subseq from] Serine hydrolase n=1 Tax=Moorea sp. SIO4A1 TaxID=2607835 RepID=A0A6B3MSI8_9CYAN +---LQKQIQTLVKQHQLQPGIFIHDLDTGAFL-ESNSRLIFPAASTIKLPILIAFFQDVD +AGKVFLDEYITMKPEMIAGGSGNMQQKPGKQYKALEVATKMITISDNTATNMLIERLGGI +EVLNQRFRSWGLKKTVLRNPLPDLPGT------NTTSPRELASLIFHLEQGKWISPQSRT +DLIDIMIQTKT-NTLLPQGLGNGATIAHKTGTLGR-LLADVGLVKMPNGKRYIISVMVKR +PFND-ASAEKLIRTISRQAYDY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis lindanitolerans TaxID=2054227 RepID=A0A2S8B6P6_9SPHN +----GDRIASLWRAFPGKTGIAVQRIDGEWAI-TQRGADLFPQQSVSKLWVAMSVLDAVD +DGRISLDQKVRIGPEDLVVHQPLAARVRSEGMSVRDLIETAITHSDNLANDSLLRTVGGP +NAVRAFITKKDLGSIRFGPGERLLQSKYLADPIDGASPAAIASALTRLARGTLLSPASTD +YLLGVMTRTHSGPKRLKAGLPPGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGT +TTSSIPARMALMQAVSGAVAE-- +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia ursingii TaxID=1756150 RepID=UPI00099AEADA +--ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNQVD +RGNLALDQKILVKKSDLLEWSPIREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGV +KTVQKLMDVNGVKNFQVKYNEEEMSKKVQAPYANYNTTASMVKTLKAFYKGMFLSKRSTA +FLMEIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLGSGKHFAIAVFVKD +SMESEEVNYGMIAQISKVVWDA- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F5CEB7_KLEPN +------------------------------------------------------------ +--------------------NPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRA---------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas mali TaxID=40682 RepID=UPI00082FA8CC +----TNLVPSLTRDFGGKVGIAVMSIDDGWTV-TSNGDLKLPQQSVSKLWVAMTVLDLRD +QGKLTLNDPYTVRKDDLTLHQPIAALVKDDGTTVGELLQRALTQSDNTANDCLLRLAGGP +TAVRAFLAKKGIADIRFGPGERLLQSRYVADPPDGAAPRAIVTALARLKKGELLSPASTQ +YLMSTMESSHTGRQRLRGAVPEGWTFGHKTGTGQTAGYNDVGFLISPNGKAYAIAVMIGD +TPKTIPQRQQLMQAVV------- +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia bruuniana TaxID=1756149 RepID=UPI000999D75B +---LKKTLESIISGKRATVGISVIGPDTKEVT-GINGDQMLPMLSTVKFPLALAVLHEVE +KGKLSMAQKLFIKKEELLEWSPFKEKYSQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHD +TYESFEASEKIISDIGRATYDYy +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000995255C +---LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVFHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLVGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVNN +TYESFDDSEKIISDIGRATWNYy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dysgonomonas sp. ZJ279 TaxID=2709796 RepID=UPI0013EB7FB0 +---LRHNIQKIIENKQATIGVGLI-VDGKDTL-TINNNHNYPTLSVYKFHLALAVLNYMQ +INNISLEHEIFIAKDDLLPHSPLRDTNPDGNMSIADLIKYSVAKSDNNACDILFKYIGGT +TKVDQYIKSIGIENCHIAATEAKMHEQFENQYLNWSSPLSAVRLLEVFRNNKFLSPIYQD +FLWKTMVETTTGSNKIKSLLPAKTLVANKTGSSFRNAENDIAIIRLPNGKYYSLAVFITD +SMENDDVNAKIIADISKTVYDY- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. PCC 7336 TaxID=195250 RepID=UPI000375DD0C +--ELQARIEGLALNPQLRLGMVVVDVEGRNYA-NVRGSERFAAASTIKLPILVALLEAVD +RGEVRLGELLTLEPSAIVGEAGSLQTQPPGSHSVLDTATWMIEVSDNTATNLIVNRLGGR +DVLNRRFRQWGLQQTQLSNPLPDLEGT------NTTSPDDLIRLLEEIERGHLLSMRSRD +RLLSIMQRTQN-ADLLPRGLGPGAIIAHKTGTLRS-LLGDVGLVDLPNGRRYAIAVLVAR +SH-SDPEASELIRQVSREVYNYw +>[subseq from] Beta-lactamase n=1 Tax=Legionella sainthelensi TaxID=28087 RepID=A0A2H5FHC0_9GAMM +--ELSQRINAIEKNSRTVMGITAIHIEKNKVI-SHNSNQRFFMASTVKLPIALAFLHRVD +ENKDSLDRVIKMDTKNSVPGSGSLHHLFEKKMSLKQVLIHMMRNSDNSASDTILKVTNGP +RYVASRMSALGFKNIFVNRSILEMFLRFQNDTRDTTTSDDMAKLLVKLYKKQALSESNTK +LLIDIMEKCRTGRSRIKGLLPAHVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS +QSASDYPRSRAIALASRAIYDHf +>[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=UPI00099A1DBD +htSILNDINAVTKDRKATVAVSVLGIENEFQFsNANGNLKMPMLSVFKFHIALSVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT +KTVQKLMDVNGVKNFQIKYNEEEMHKNVKALYANYTTTASMVKTLKAFYKGLFLSKRSTI +FLMDIMTKTNTGMTKLPGLLP-KVKMARKTGSSGTVAENDSGIVTLANGKHYAIAVFVKD +SMESEEVNCGMIAQISKIVWDT- +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia TaxID=308865 RepID=UPI00099A1D50 +---LKKTLESIISGKRATVGISVIGPDTKEVT-GINGDQMLPMLSTVKFPLALAVLHEVE +KGKLSMAQKLFIKKEELLEWSPFKEKYSQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHD +TYESFEASEKIISDIGRATYDYy +>[subseq from] Beta-lactamase n=1 Tax=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) TaxID=63737 RepID=B2J7F0_NOSP7 +---LKNAVQNLAANYNLAPGVFLVDLDTGNYV-DVNGSTSFPAASTIKVPILLAFFQDVD +AGKIRLDEMLTMQQDMVAGGSGDMGSKPAGTYNALEVVTKMITISDNTATNMLIARLGGM +EALNQRFRTWGLTTTTIRNSLPDLQGT------NTTSPKELANLMAIVSQGNLVSMPSRD +LMLDILRRTQR-DTLLPSGLGTGARAFHKTGDIGT-MLADTGLIVVPTGKRYIASVMVQR +PEN-DPRAEKLISSISRAAYQEf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Bacillus pumilus TaxID=1408 RepID=A0A2L0NG81_BACPU +--------------------------------eSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDXRDTTMPVAMATTLRKLLTGELLT----- +------------------------------------------------------------ +----------------------- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides TaxID=816 RepID=UPI0007C4E695 +---LKTEIRHIIKDKKATIGVALI-LDGEDTL-AVNNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKRYFKPYSPLRDKYPQGNLPISELLAYTMQLSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITTTEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDSMKNEYTN +FLKHIMIECETGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGNRYVVAVFVKD +SKENMETNTKIISDISAAIYRY- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Bathyarchaeota archaeon TaxID=2026714 RepID=A0A497KLV1_9ARCH +--SLQAAIEEQAEGFKGTLGVSVKHLYTGETA-SINGDKVFPTASVFKIPVIVEFFRQVD +AGTLSLDQQLLLSERDKVPGSGVLKELTEGLVTYKDLLSLMMIVSDNTATDLITEIV-GF +ENINATMKELGLKETQVTRYCRQILFSLETEDNDVTTPNEMNRLLELIVDGKAASRENCN +KILEIMEKCQTGGYRIPKYLPKEVRLQRKTGSLP-GIRNDVGIVTIKETEKYTITCFTMD +AE-DVYAAEEVLAKVSKAVYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI00099A6C6B +-nELKKRIENIITGKKADVGVSIIGGNKNDKL-QINGNQLYPMLSTFKFPIALTVLHKVE +KGELKMSQKIFIKKEELLDWSPFLEKYPQGNITLEDALMWMMCYSDNNLTDILIRLIGGT +DTVQKF---IGTKDFIIKNDEEDMHKDWDSQFINKITPNRATQLLDKFYQGKILNGVNTK +WLYEAMLNNKTGLKRLKGKLAADIKVAHRSGTSFTAAINSYGIIELPKNKKIVITVFVHD +TYENFNDSEAIIADIAKTVYDYy +>[subseq from] serine hydrolase n=1 Tax=Nostoc punctiforme TaxID=272131 RepID=UPI000A047337 +---LKNAVQNLAANYNLAPGVFLVDLDTGNYV-DVNGSTSFPAASTIKVPILLAFFQDVD +AGKIRLDEMLTMQQDMVAGGSGDMGSKPAGTYNALEVVTKMITISDNTATNMLIARLGGM +EALNQRFRTWGLTTTTIRNSLPDLQGT------NTTSPKELANLMAIVSQGNLVSMPSRD +LMLDILRRTQR-DTLLPSGLGTGARAFHKTGDIGT-MLADTGLIVVPTGKRYIASVMVQR +PEN-DPRAEKLISSISRAAYQEf +>[subseq from] Class A beta-lactamase n=1 Tax=Erythrobacter sp. YT30 TaxID=1735012 RepID=A0A120GAE0_9SPHN +--RLQSRMRIIEANAGGTLGAELFDAASGLSI-GLNQDRRFGHCSSFKLSLAAKILSANA +AGEIDGNKLIRWSEDDLMFVSPFTTQRLDEGATMLELAEFTQKYSDNAAANILLRELGGP +AALTGFWRSIGDDVSRLDRTEPALNNVPVTEVRDTTTPAAMARTVAKLIYGDALPDAERA +ILKQWMIDTPTGVRRVRAGLEEGWVAGDKTGTSFGSLYVDIGFAEAPQKPPITFATYYRA +RETHDPASEATLAQVGKIISD-- +>[subseq from] Beta-lactamase family protein n=1 Tax=Blastomonas sp. RAC04 TaxID=1842535 RepID=A0A1B3N3Z2_9SPHN +--GLRDELAQLWRSFPGKTGIAVRRIDGDWVV-GHRGGELFPQQSVSKLWVTMAVLEKVD +RGELSLDTEVTITPEDLTLHQPLAARVAREGESVRTLINEALTASDNSANDALLRTAGGP +GVVNDFLRRKGLSSIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQNSTR +LMLDTLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLGE +TTAGIPARMQLMQAVSRAV---- +>[subseq from] Uncharacterized protein n=2 Tax=Chroococcidiopsis TaxID=54298 RepID=A0A433V6I5_9CYAN +----------------------------------------------------MAVLNQVD +RGNLKLDQKIRIEASDIVQGSQVLDENSQGKFSLSELLQYMVSKSDNTACDVLLRLIGEP +QRVTEYLSSLGINDIVVANTEKELAQDSTVQYRNSATPDAAVVLLRTLYEGRGLSKTSQA +LLLQWMTEAQTGLKRIKGLLPEGTVVAHKTGTSSTAATNHVGLVTLPSGQHLAIAVFVSN +SQATDVIREEVIAKVARAAWDEw +>[subseq from] class A beta-lactamase n=1 Tax=Propionibacteriaceae bacterium NML 020265 TaxID=2016499 RepID=UPI000B97A94E +------LIADLERRHDVRIGLSAAALTRGRRL-DHRADERFLMLSVFKAIAAAAVLDGIT +PDPKVLDRPVFLPPEAICEGPTWFEQIAARRPSVAEVCRAAIQLSDSTAANALMSLTGGP +ASITRFARDNGDTITQLTEWEPELNT--PNGDRNTTSPRAIGALFAAMIVGRALRTSARR +RLTDWMLGNQTSDQRFRAGLPAGWTLADKTGSGIDATANDVGIAFDPAGNAYQLAVLTSS +PRPDTERVNEIFAILAR------ +>[subseq from] serine hydrolase n=1 Tax=Sphingobium vermicomposti TaxID=529005 RepID=UPI001422B2BC +--RLLAEFARFATLTDGTVGIAVRDLHSGQSI-GINNDTLFPMASTYKVAVAGKIFALAD +AGALSLDERLP---------------RLGTPLSVTTLLELMLTRSDNEATDVLVARAGGP +QAVNSWLQSIGIRGQRVDSNTAQLLAAFAADPRDTSTPRAMNDLLSAIHHGRALKASSSA +ALIAIMARCKTGKARLAGMLPPGTMIAHKTGTLN-GLGNDTGIISLPDGRIFAISVFVMK +DRRGHVLRDRIMAEVARAAYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter halimionae TaxID=1926630 RepID=UPI00135DDE0D +--TLDRQLSEIGSRFAGQVGIAVRPVEGDRTM-QYRGLELFPQQSVSKLWVSLTALRQVD +AGKLSLDEARVVTLEDLTLHQPIRDEVLASGTEYRDLMQRALTRSDNTANDIILRRVGGP +DAVQATLNRLGLSSIRFGTDERTKQSGYLADPIDGAAPVAIAAALTRLAKGELLSKDSTA +LLLDTLAETRSGPNRLKGGLPPDWRIAHKTGTGQQTGYNDIGILTAPDGRRYAVVVMIAR +TEERVPDRMAMMHEVVGAVAEY- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Elusimicrobia TaxID=1797919 RepID=A0A1F9QFS1_9BACT +---LVEDLEKASRAYSGRVGIYIKDLETGKSW-EYNADRRFPSASLIKVPIMAAVFESIR +GGRLSLDTQIKLTRGLRVGGSGSLKWVREGTLSVMEIIYKMITESDNTATKMLIDAV-GM +DYLSGAFRAMNLEQTNITPEGMSLSSR-PVRRENYTTAREMGGLMERIYAGKLVDREASE +FMLDVLKHTKS-RSRLRRGLPLGWEIGHKTGLLRK-ACHDVGVVFSPRGD-FVIAVLTSE +VP-SYSSAKTFISRVAKLTYKYy +>[subseq from] Beta-lactamase n=3 Tax=Bacteroides TaxID=816 RepID=A0A4V6P7U6_9BACE +---LKTEIRHIIKDKKATIGVALI-LDGEDTL-AVNNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKRYFKPYSPLRDKYPQGNLPISELLAYTMQLSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITTTEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDSMKNEYTN +FLKHIMIECETGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGNRYVVAVFVKD +SKENMETNTKIISDISAAIYRY- +>[subseq from] Serine hydrolase n=1 Tax=Anabaena sp. CRKS33 TaxID=1710888 RepID=A0A1B7WCZ0_9NOST +---LKNTLQSLAANSDLTPGVFLLDLDNGAYV-DINGNTSFPAASTIKIPILMAFFQDVD +AGKIRLDEMLTLEKEMIVGGSGNLQYQAPGGYTALDLATKMITISDNTATNMLVAKLGGQ +ETLNGRFRSWGLTTTMIRSPLPDLQGT------NTTSPRELGNLISMVNQGNVVTMRSRD +LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVQR +PNND-PRAAKLISSISSSAYQYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sartorii TaxID=671267 RepID=UPI001363C902 +-kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD +FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD +SKENMETNAKIISDISAAVYRY- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A395UNM2_BACVU +-kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD +FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD +SKENMETNAKIISDISAAVYRY- +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides TaxID=816 RepID=A0A412E085_BACSE +-kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD +FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD +SKENMETNAKIISDISAAVYRY- +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides TaxID=816 RepID=A0A397WFK9_BACVU +-kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD +FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD +SKENMETNAKIISDISAAVYRY- +>[subseq from] Beta-lactamase n=8 Tax=root TaxID=1 RepID=A0A0P0M3W0_BACVU +-kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD +FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD +SKENMETNAKIISDISAAVYRY- +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. Fuku2-ISO-50 TaxID=1739114 RepID=A0A102D8X3_9SPHN +--AIQQAVEAITARAHGRIGVAAADLDGGGQV-LINGDMPFPMASTAKIAVAGTFLTGVE +QGRFRLDQSLPMMMPVAERRGSSAPLRAGPVMSAQQLMELMITRSNNNATDGLITAVGGV +STVNAWLARNGIVGQHLDSTMATLVRAKTIDTRTASTPRAMLALLSAIDRGTALSPQSRA +VLLDTMTRTSTGKNRMRAGLPDGTVFAHKTGTLA-GVTDDVGIIRLPDGRHLALAIFIAG +PE-SHTSHAMMIADITRALYDGy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A224A905_SHISO +------------------------------------------------------------ +-----LNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTQ---------------------- +----------------------- +>[subseq from] Beta-lactamase class A protein n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' N6 TaxID=1261031 RepID=A0A2L2N835_9NOSO +--SLKNAVQNLATTNNLTPGVFLVDLDTGNYV-DVNGSTSFPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMQQDAIAGGSGTLQYKPAGTYAALEVVTKMITISDNTATNMLIAKLGGI +EALNQRFRSWGLTTTTIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSVPSRD +LMLDILRRTEK-NTLLPSGLGTGARAYHKTGDIGT-MLADTGLIVVPTGKRYIASVMVQR +PEN-DPRAEKLISSISRAAYEEf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. UV9 TaxID=1851410 RepID=A0A4Q0GKJ9_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIIRSDNQATDQLLATLGGP +VAIQQWLSSHQIPGIRMDRTIAQLLRGHLADSKDVATPVAMVTLLNKLDNGTVLTAQSRA +FLLELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAIFARG +GR----DRQPVIAEVARVIYDRf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000CD2D16C +----------------------------------------------FKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6HWU0_9BACT +----PSQFEKIAPAAKGPVGVAAQLLESGETA-SLHGDEHFPMHSVYKLPISMAVLQRVD +RGELKLDQHVKVEPSDFARSSPVRDKYPGGTLTIAELLRYTICESDGSTSDVLMKLIGGP +AKVMLFLEGIHVSDIQVVNYEKEIGRDWETQYRNWATPKGALALLAALQSQRGLSRESQG +LLLKLMTEAIPGAKRLKGELPAGTVVAHKTGTGGTQATNDIGIITLPDGRHLAVAAFVSD +SAADDN----------------- +>[subseq from] class A beta-lactamase n=1 Tax=Prevotella paludivivens TaxID=185294 RepID=UPI00036B1219 +--TIKDKINNVINNKNAGIGVAILDLNSNESV-VINGEEHYPMQSVFKFPIALKVLNDVD +NDKIKLSDSIFISSAELKKWSTIQEKYPNGNMALSDIIYYMVAISDNIGCDVILKNNGGA +SSINHYLRSIGVNNMTIKINEAEQQAKPDKQFQNWATPNEAINLLTMFYKHSLLKPATQN +FLWDTMKKTATG--SIKNKLPKGITVIHKTGSAPTAVNNDIGIMVFPNKKAVAYAIFIKD +SKETSDTNYNIIAEIGKIIAE-- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Dysgonomonas mossii TaxID=163665 RepID=A0A4Y9ILP3_9BACT +---LRNKIQKIIQGKDATVGVAII-VDGKDTL-TINNNFRYPTQSVYKFHLALAVLDYLN +KNNLTLDHQLYVKKGDLLPHSPLRDDYPQGELSVADIIRYTVSKSDNNGCDILFRLVGGT +AVVDRYIRGLGLSEFAIAATEEEMHGPWEVQYTNWSTPYTAAQALEIFRTHDILPQPFHD +FLWDALAGTTTGGNKIKALLPEGTFVAHKTGSSFRNAENDIAIIQLPDGRYYSLVVFVAD +SMESNDVNCGIIAQISKAVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' 213 TaxID=2014530 RepID=A0A235IGX3_9NOSO +--SLKNAVQNLATTNNLTPGVFLVDLDTGNYV-DVNGSTSFPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMQQDAIAGGSGTLQYKPAGTYAALEVVTKMITISDNTATNMLIAKLGGI +EALNQRFRSWGLTTTTIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSVPSRD +LMLDILRRTEK-NTLLPSGLGTGARAYHKTGDIGT-MLADTGLIVVPTGKRYIASVMVQR +PEN-DPRAEKLISSISRAAYEEf +>[subseq from] Serine hydrolase n=1 Tax=Rhodanobacter sp. C06 TaxID=1945854 RepID=A0A1V3PC73_9GAMM +haALQGKLDALSRRTPGVFGIVVLDPRSGERW-RVNADRAYPMMSVFKAPVAAAVFAQID +SGKLSMERAITLTRADIVGGSPSIGAHFHGGFTVRQLLAAAVSDSDNTAVDALLKLV-PP +QDVTAFLRAHGIAGMRVDMGEAGVDGAYLADPRNRSTPDAAADFLRQLQHGTLLSPSSTR +ALLALLQAQTQ-PDRMRQGLPHDVQLADKCGTSYTAAYNDIGILTWPDGRSVIVAAFLTA +STGSKAQREALFADLARTIAD-- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Sphingomonas TaxID=196159 RepID=A0A0Q4R3P9_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIIRSDNQATDQLLAALGGP +GAIQQWLSSQNITGIRMDRTIAQLLRGHLADSRDVATPVAMVTLLNKIDNGTVLTAQSRT +FLLELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG +GR----DRQPVIAQVARAIYDRf +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus sp. Leaf182 TaxID=1736290 RepID=UPI0006FB97B7 +---WQQVVENVLKEAPGIFGIAAMHLETGETA-GHLDEELFQLASAFKIPIMVTLMREVE +AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI +DKVNEHMHELGLSQIHLRHNCWELLNSMPTRENNVATPAELNRLLIMIARKEILTEASCE +LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR +GVTDKEAAELTIARVAKAIYE-- +>[subseq from] serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' N6 TaxID=1261031 RepID=UPI000CF31DC1 +--SLKNAVQNLATTNNLTPGVFLVDLDTGNYV-DVNGSTSFPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMQQDAIAGGSGTLQYKPAGTYAALEVVTKMITISDNTATNMLIAKLGGI +EALNQRFRSWGLTTTTIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSVPSRD +LMLDILRRTEK-NTLLPSGLGTGARAYHKTGDIGT-MLADTGLIVVPTGKRYIASVMVQR +PEN-DPRAEKLISSISRAAYEEf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A1Y4X676_BREBE +---WQQAVENVLKEAPGIFGIAAMHLETGETV-GHLDEELFQLASAFKIPIMVTMMREVE +AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELIGGI +DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE +LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEEKGMIAITALSR +GVTDKESAELTIARVAKAIYE-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas oligophenolica TaxID=301154 RepID=A0A502CMZ7_9SPHN +------------------------------------------------------------ +--------------------------------SAAKVMELMIVRSDNHAADQVLATLGGP +VALQRWLSSQGMTGIRVDRTIAQLLRGHLADSRDVATPVAMVTLLRKLDNGTVLTAQSRT +FLLELMSRCATGTRRIRALLPTGTQVEDKTGTLD-GITNDVGIITMPDGHRVAIAVFARG +GR----DRQPVIAEVSRAIYDRf +>[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. DC-2 TaxID=1303256 RepID=UPI0004C46C77 +------------------------------------------------------------ +---------------------------LGTPLPVTALLELMLTRSDNEATDVLVARAGGP +QAINSWLQSIGIHGQRVDSNTAQLLEAFAADPRDTSTPRAMNDLLAAIHHGKALKPGSSA +ALLAIMARCKTGKARLTGMLPPGTQIAHKTGTLN-GLGNDAGLIALPDGRTFAISVFVMK +DHRGHVLRDRIMAEVARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas paucimobilis TaxID=13689 RepID=A0A031JEL1_SPHPI +---LLGEFERFAALTDGTVGIAVSDLHSGQSI-GINNDTLFPMASTYKVAVAGKIFSMAD +AGALNLDERLP---------------RLGTPLPVTALLELMLTRSDNEATDVLVARAGGP +QAINSWLQSIGIHGQRVDSNTAQLLEAFAADPRDTSTPRAMNDLLAAIHHGKALKPGSSA +ALLAIMARCKTGKARLTGMLPPGTQIAHKTGTLN-GLGNDAGLIALPDGRTFAISVFVMK +DHRGHVLRDRIMAEVARAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Legionella gratiana TaxID=45066 RepID=A0A378JN91_9GAMM +--ELSKRINVIEKNSHTVMGITAIHIEKNKII-SHNSNQRFFMASTVKLPIALAFLHRVD +EKKDSLNRIIKMDTKNSVPGSGSLHHLFEKKMSLKQVLIHMMRNSDNSASDTILKVANGP +KYVASRMNALGFKNISVNRSILEMFLRFQNDTRDTTTSDDMAKLLVKLYKKQALSESNTK +LLIDIMEKCRTGRSRIKGLLPAHVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS +QSASDYPRSRAIALASRAIYDHf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonadaceae bacterium KCTC 52780 TaxID=2172047 RepID=UPI000E0D47A2 +-qSLEQRLAALATENPGEYGIAALDLQTGAMV-SFNGNEPFPMASTMKIAVAAAYLEEVD +AGRRSLADEI-------------------GGVTVHSLMDSMITRSNNRATDILMNALGGP +AAIDGWLRRHRLTGIRVDRTIAQLLADRRRDIRDSSTPEAMLGLLRLIASGDALSTNSRA +LLLDMMRRCATGSNRIRGLLPPGAQVAHKTGTLN-GYTGDVGYFTTPEGRRIAVVFFARY +GE----NRPAVISTAARAIYDAf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides intestinalis TaxID=329854 RepID=A0A414LIV0_9BACE +-qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KGHIALDSLIEVKSSQLKSYSPLKDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI +DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD +FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQETDTDNAAIIASISKIVHD-- +>[subseq from] Beta-lactamase n=8 Tax=Bacteroides TaxID=816 RepID=B6VZN3_9BACE +---LKTEIRHIIKDKKATIGVALI-LDGEDTL-AVNNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKRYFKPYSPLRDKYPQGNLPISELLAYTMQLSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITTTEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDSMKNEYTN +FLKHIMIECETGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGNRYVVAVFVKD +SKENMETNTKIISDISAAIYRY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingorhabdus sp. M41 TaxID=1806885 RepID=A0A127MGN2_9SPHN +--ALVREIDQLWRTFPGKTGIAVKRIDGGWEF-GHRSDEYFPQQSVSKLWVAMAMLDKID +QGRASLSDPIRIGKEDLTVHQPMAVEVEREGKSVYTLLEKALASSDNTANDALLRHAGGP +DAVRRFIAKNSLGKIRFGPGERLLQSAYLADPVDGASPIAIVRALDKLARGELLSDNSTK +LLQSILKRTRSGPNRLKAGVPAGWEFLHKTGTGQATGYNDIGIMTAPDGTRYAVVVMMGD +TTASIPERMRMMQAVTRAVARY- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WQP1_9BACT +--ELTKLLRSLCDAVAGDIGVAVVHVESGKIV-TVAGDKKLPLYSVYKLPLAITVLREIE +AGKLRLDQKVKVNPADIAGVQFNTDLWRGTQKTVRELIEYAIVRSDNTSADKLLGLIGGP +PIVTQQMRTIGLANIDVVVTSREFTAH--RDKPNTGTTTDLAQLLARLQKGELLQPAKVS +LLRDYMERSKTGERRLRANLPAGTQVADKTGTGDV-ATNDVGLITLPNKGHLAIAVLISG +SKLPVDKQEKTIADIARAAYDSf +>[subseq from] Beta-lactamase class A n=2 Tax=Bacillus oleivorans TaxID=1448271 RepID=A0A285CJJ8_9BACI +---LQQMLNEIVQSSSGTYGVAVKHLDTGEFA-GVNQHERFQLASTFKIPILVTLFRDVN +SDKLELEDIVTVQEEDIVIGSGVIQHHPRVQFTIKDLATLMIIVSDNLATDLILKLV-GT +ENVTSYMKELGLSNTFIHFSCRQLLNFQGDSRNNVSTPVEMAMLVEKIARKEIISEKSCD +AMLDILLKQQF-NSRLPYLLPSRTKVAHKTGTIGN-VINDVGIVYLPEGGAFSIAVLSKE +SV-SMEEGERTIGRIAKAAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. LC81 TaxID=1502850 RepID=A0A095CZ57_9SPHN +---LNDRIFELWRAFPGKTGIAVQRIDGEWSL-SQRGAELFPQQSVSKLWVTLTVLDAVD +QGRMTMDQRVRIGPEDLTLHQPIAARVRAEGMSVRDLIETAITHSDNTANDSLLRTVGGP +SAVRAFVAKKDLGSIRFGPGERLLQANYLANPVDGASPAAIASALTRLARGTLLSPESTE +YLQGVMSRTRSGPRRLKAGLPPGWQFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGS +TTSGIPARMALMQSVSSAVAEY- +>[subseq from] Class A beta-lactamase n=1 Tax=hydrothermal vent metagenome TaxID=652676 RepID=A0A3B0TAD0_9ZZZZ +--ALVHEIADLWRTFPGKTGIAVKRIDGAWEI-GHRANQSFPQQSVSKLWVAMTMLDKID +QGRASLSDAIRIGPEDLTLHQPLAAEVRREGKSVYTLLEKALAHSDNTANDALLRHAGGP +EAVNRFIQRSKLGRIKFGPGERKMQSAYLADPIDGASPSAIVNALDKLARGELLSQNSTR +LLLSILSRTRSGPNRLKAGVPSGWKFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLGD +TTAPVPERMRMMQAVTRAVARY- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T5E5_9BACT +--PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLEHLD +KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT +SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK +FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD +SMEDDKTNAAIIAQISKAVYDY- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacteroidetes bacterium HGW-Bacteroidetes-20 TaxID=2013689 RepID=A0A2N2XYZ5_9BACT +--ALNDTIGKIISNKKATVGVVVAN-KNGIIVaEKNGAQHFPMQSVFKFHIAIVMLSEIE +KGKFTLDQPIEIKKSDLQVWSPIRDKYPNGTLTIREIIQYTVSQSDNNGCDILLQLLGGP +KVVENFFKEKRFSDISIQINEAQMHTKWNEQFKNWITPYTSNAILFQFNMQTFLTPIHKT +FLLETMINTTTGMGRLKGLLPPSAVVAHKTGSSGTAAANDIGIVFVDKENWYVISVFVTQ +SSENEVVNDQIIAEISKAVWDHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A346TJ64_KLEPN +------------------------------------------------------------ +---GLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDLAVV---------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Gloeocapsopsis sp. AAB1 = 1H9 TaxID=1433147 RepID=UPI000CF6A175 +--SLKTTVEQLAAQKNLLPGVFFVDLDSGSYL-DINGSSNFASASMIKVPILVAFFQDVD +AGKIRLDESLTLKKELIGGGSGDMQKPLETKFTALETATKMITISDNTATNLLIERMGGI +AALNQRFLSWGLTATQIRNLLPDLEGT------NTTNPKDLAHLMALVNQGDLMSLRSRD +RLLDIMRRTVT-NTLLPRGLGEGATIAHKTGDIGS-LVGDVGLVDMPNGKRYIAVAMVKR +PHND-GRAQELIRQISRAAYQEf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0005E2E40D +---------------------------------------------TSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-CC-3A-396 TaxID=2135655 RepID=A0A4R2UKR5_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIIRSDNQATDQLLAALGGP +AAIQQWLLSLQIPGIRMDRTIAQLLRGHLADSKDVATPVAMVTLLNKLDNGSVLTAQSRN +FLFELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG +GR----DRQPVIAEVARVIYDRf +>[subseq from] Beta-lactamase n=1 Tax=Dolichospermum planctonicum TaxID=136072 RepID=A0A480AI97_9CYAN +---LKNTLQSLAANSDLTPGVFLLDLDNGAYV-DINGNTSFPAASTIKIPILIAFFQDVD +AGKIRLDEMLTLEKEMIVGGSGNMQYQAPGGYTALDLATKMITISDNTATNMLVAKLGGQ +EALNGRFRSWGLTTTMIRSPLPDLQGT------NTTSARELGNLISMVNQGNVVTMRSRD +SMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVQR +PNND-PRAEKLISSISSSAYQYf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf242 TaxID=1736304 RepID=UPI0009EA4889 +------------------------------------------------------------ +---------------------------------AAKVMELMIIRSDNQATDQLLAALGGP +GAIQQWLSSQNITGIRMDRTIAQLLRGHLADSRDVATPVAMVTLLNKIDNGTVLTAQSRT +FLLELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG +GR----DRQPVIAQVARAIYDRf +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-F2F-G114-C0414 TaxID=2135662 RepID=A0A3M0EC68_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIIRSDNQATDQLLAALGGP +GAIQQWLSSQNITGIRMDRTIAQLLRGHLADSRDVATPVAMVTLLNKIDNGTVLTAQSRT +FLLELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG +GR----DRQPVIAQVARAIYDRf +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-CE-3A-406 TaxID=2135659 RepID=A0A3M0FQN5_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIIRSDNQATDQLLAALGGP +GAIQQWLSSQNITGIRMDRTIAQLLRGHLADSRDVATPVAMVTLLNKIDNGTVLTAQSRT +FLLELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG +GR----DRQPVIAQVARAIYDRf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. LK11 TaxID=1390395 RepID=A0A1P8PQY4_9SPHN +--ELVSTINRLSASFAGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD +RGRARLDEPIVVRREDLTVHQPIAMLVKGDGTTVGELLNRALTMSDNTANDRLLTYVGGP +QAVRAMIAAKRLGDIRFGPGERLLQAAYVSDPPDGAAPIAIADALARLARGELLSETSTR +ILIDTMEASRTGHARLRAAVPSGWQIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD +TTEDIRKRQQLIQNVAAAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sartorii TaxID=671267 RepID=R9I1T0_9BACE +-kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AVNNAEKYPMMSVYKFHQALAVCDYLQ +KQHIPLSTSLYLDKRYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDPMKNEYTD +FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVTLPDGSRYVVAVFVKD +SKENMETNTKIISDISTAVYRY- +>[subseq from] Beta-lactamase n=1 Tax=Sphaerospermopsis kisseleviana NIES-73 TaxID=1973480 RepID=A0A1Z4UK18_9CYAN +--TLKSTLQNLATANSLTPGVFMVDLDTGDYV-DINASTSFPAASTIKIPILVAFFQDVD +GGKIRLDEMLTMEKEMVAGGSGNLRTPVGSKYTALDVATKMMTISDNTATNMLITRLGGQ +EVLNGRFRSWGLTTTAIRNILPDLEGT------NTTSPKELADLIAKVNQGNLVSMRSRD +LMLDIMRRTER-NTLIPSGLGEGARAYHKTGDIGT-MLGDAGLIDIPTGKRYIAAVMVKR +PHND-SAAETLISSISKAAYENf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Prevotella sp. 10(H) TaxID=1158294 RepID=UPI0004A70B17 +--KLRKEISGIIGGKDAKVGVALI-VDGKDTL-TVNNNFHYPTQSVYKFHLALAVLDYLD +KNNMTLDHKISVKKSDLLPHSPLRDDYPEGNLSVGEILRYTVSLSDNNGCDILFRFIGGT +DVADKYIRNLGMTDFAIAATEEEMHGPWEVQYTNWSTPYTATLVLEKFRTGNILPQPFHD +FLWSIMTDSPTGKNKIKALLPEGTVVAHKTGSSFNAAENDIAIVQLPDGRCYSLAVFVAD +SMESSYVNCKMIADISKAVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. BC25 TaxID=1144308 RepID=J2ZM28_9BACL +---WQQAVENVLKEAPGIFGIAAVHLETGETA-GHLDEELFQLASAFKIPIMVTLMREVE +AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI +DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE +LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR +DVIDKEAAELTIARVAKAIYE-- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas sp. JUb134 TaxID=2485112 RepID=A0A4V2TJV2_9SPHN +--DLTRAITTLLANFNGTAAAAVTSIDQGWTV-AYNGNRPMPQQSVSKLWVAMTALDLLD +QGKLTLDDPVVVRREDLTLHQPIASLVKGDGTTVRELMRRALTMSDNTANDRLLTYVGGP +NAVRAFLARRGIQNIRFGPGERLLQSAYVANPPDGAGATAIAEALMRLKQGKLLSANSTR +YLLDTMAASRTGRARLHAALPPGWTLAHKTGTGQNAGFNDVGILTAPDGRSYAVAVLIGD +TRAPMRDRQQLIQQVVHALV--- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas oligophenolica TaxID=301154 RepID=A0A502CCM5_9SPHN +--QLTSAIDALARGFSGKFGIAVRAVDEGWTV-EETARQRLPQQSVSKLWVAITLLDLRD +QGKARLDDPIVVRPEDLTLHQPIAGLVKGDGTTVGDLLTRALTHSDNTANDRLLSYVGGP +QAVRAMIERKQLGDIRFGPGERLLQSAYTADPPDGAAPIAIADALARLARGEVLSETSTR +IMLDTMGNSVTGRARLRAALPGGWGIAHKTGTGQNAGFNDVGLITAPDGRRYTIAVMIGD +TRESVRSRQQLIQAVANAVAT-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides cellulosilyticus TaxID=246787 RepID=UPI0012313728 +---LKADFDKLLQDKQATVGVAVVS-DGRKTF-TYNNQHHFPLMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKRYFKPYSPLRDKYPQGNLPISELLAYTMQLSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITTTEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDSMKNEYTN +FLKHIMIECETGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGNRYVVAVFVKD +SKENMETNTKIISDISAAIYRY- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. 3F27F9 TaxID=2502209 RepID=UPI0010F54884 +--ALVANVAALVRGFDGRVGVAVRSIEEGWAV-DTGGEQRLPQQSVSKLWVAMTVLDYRD +AGRLKLEDPITLTRDDLTVHQPIAALIKGEQTTVGELLQRALTMSDNTANDRLLRYVGGP +NAVRDFLQRKRLGDIRFGPGERLLQSRYVSDPPDGAAPRAIAEALARLKRGDLLSRSSTE +YLLATMESSHTGKQRLRGAVPAGWTFGHKTGTGQTAGYNDVGLLIAPDGRSYAIAVMIGD +TPKPIPARQALMQAVVASVVA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. TF3 TaxID=2495580 RepID=A0A432VGN4_9SPHN +--ALVANVAALVRGFDGRVGVAVRSIEEGWAV-DTGGEQRLPQQSVSKLWVAMTVLDYRD +AGRLKLEDPITLTRDDLTVHQPIAALIKGEQTTVGELLQRALTMSDNTANDRLLRYVGGP +NAVRDFLQRKRLGDIRFGPGERLLQSRYVSDPPDGAAPRAIAEALARLKRGDLLSRSSTE +YLLATMESSHTGKQRLRGAVPAGWTFGHKTGTGQTAGYNDVGLLIAPDGRSYAIAVMIGD +TPKPIPARQALMQAVVASVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A2Z4MMX4_BREBE +---WQQAVENVLREAPGIFGIAAVHLETGETA-GHLDEELFQLASAFKIPIMVTLMREVE +AGRIRLDQRVTLRWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI +DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEDSCE +LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR +GVTDKEAAELTIARVAKAIYE-- +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium Mal48 TaxID=2527994 RepID=A0A517QJN9_9BACT +---LKDSLTSLVESFEGEAGVAVKHIPSGETV-LINADEAMPTASLIKISVMIEAYRQVE +AGKLDLAALITLKKEDKVPGSGVLTTHFSPGLSLRDAIRLMMAYSDNTATNLVIDQV-GL +KSVSDTMEELGFPETKIHSKVYRGSTRSKKYGLGSTTARETMNILEKLSQSEFTNEKFNK +EMLEHMRKCIN-RDRIPPFLPRRTVVAQKTGSIST-ARTVAGIIESPSG-PIIVVVLTAK +GNRDGKTTDMLMASISKRAFDYf +>[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium zucineum TaxID=284016 RepID=A0A2W5NUA5_9CAUL +-----------ARARPGVLGVGLANLESGQVY-LFNGERRFPMQSVFKLPLAMAALAEVD +AGRALLTERIQILEEQLSAYSPIGAAWPARRFTFRELLEAVLVESDNTAADVLMKRIGGP +GAITAWLDARRVPEVRVDRYERELQCRYLADPRDTATPRGMIEFLRMLDQDELAEPQSTR +LAMGLMARTPRAPNRIRAGLPRDAFLAHRPGTAGSAAHNDVGIFRLADKRAYALAVFLSG +ATLDEAGRDTVIAEVARAAVA-- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. TaxID=29523 RepID=A0A3C0E2M8_9BACE +-qELYTNIHQFISQQKAEVGVAIIA-DGKDTV-TVENNRRYPLMSVFKLHQALAVGDYCK +RHQISFDTLLTVDSTDLQPYSPLRDQYPHGGFSLKQLMEYTLHLSDNNACDILFKFTGGP +AVTDRYIRSLGINDFSIQYTEDDMHQDLNLGYENWSTPLATAEVIEALLTQTLFDKPHQE +FIKEALVTCQTGTNRIVHPLQKQVTVGHKTGTGDRNAINDAGFVQLPNGHRYTLVVFVKD +SQESMEDTEAIIAQISEMVYQAf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium 24-56-14 TaxID=1970588 RepID=A0A258Z7V6_9SPHN +---LENLIQDQWRLFPGRTGVAIMRVDGGEWVlGRRMDELFPQQSVSKTWVALTVLDMVD +QGKLRLDQKVRITRDDLAVHQPIRDQVIANGVSVLNLLETSIRASDNTANDSLLRTVGGP +QAVKSFIARKNLGAIRFGPGERALQSRYLNDPIDGASPQAIVRALAKLAKGELLSASSTR +LMLDIMSRTSSGPNRLKAGVPAGWSFLHKTGTGQSTGYNDIGIMTAPDGTRYAIAVMMGS +TTASIPQRMTFMQFVSRTVASY- +>[subseq from] Uncharacterized protein n=2 Tax=Planktothricoides sp. SR001 TaxID=1705388 RepID=A0A0M1JWI4_9CYAN +--QLKNEIQTLSASYQLTPGVFFVDLDTGAYL-DMNGNNTFSAASTIKVPILIALFQEVD +AGKIRLDEPLTMQAEYVAEGSGDMQDPVGTQYTVLETARKMITISDNTATNMLIARLGGQ +NVLNQRFQSWGLASTQIQNFLPDIQGT------NTTSPKDLVSLMAMVEKGGLLSLRSRD +RVLDIMQATEN-NSLLPQGLGDDATIAHKTGNIGS-VLADTGIVDLPNGKRYLASVIVKR +PH-DDPGASELIRQISQAAYQSf +>[subseq from] Beta-lactamase n=4 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A174WNU4_BACVU +-kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITATEDEMHQGMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD +FLKHIMIECGTGKDRLPASLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD +SKENMETNAKIISDISAAVYRY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Tannerella sp. AM09-19 TaxID=2293249 RepID=UPI000EFDB684 +-rELKMRIASVLKEKRAIVGVAVLY-GDNRLF-EVNRG-DYPMMSVCKFPLALAVLDYLH +KNNLSLDTDIFIRESDLLPYSPLRDRHPQGNMSIRELLSYTVSLSDNNACDILFGYIGGT +KVVDDYIKRLGISGMSVVATEAVMHESFEKQYCNMATPSSAVLLLDKFLKEDLFRDEYGS +YLRKIMIETSTGNDKIKAGLPEGVVMGHKTGSSDRNGDNDLAFVQLPDGQRYCIAVFIRN +SKEDDKTNAAIIASVSKVVYDY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Oceanobacillus oncorhynchi TaxID=545501 RepID=A0A2L0NGV8_9BACI +-----------------------------KILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGEL------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A5C7M6M3_9GAMM +--DFEARLYNAADGSNGRIGVAVIDLGTGRTV-SVLGDTPFPMASTSKIAVASTFLDGVD +KGKWTLDDKFPLMIPVGSAFSGSKAPRPGEMLTARRLIELALINSSNPATDALLAAVGGP +AAVNRWIKTTGVEGMRIDRDIATLVRARTVDLRDSAPPVARAQLLAGLFQGQWLSQRSRA +FLRGTMERCVTGKRRMRALLPSDARIAHKTGTLNN-TASDVGIIQAPDGHAYAVAIYVTG +QG-GKPNRDARIASIARTIYQ-- +>[subseq from] serine hydrolase n=1 Tax=Sphingopyxis sp. Z10-6 TaxID=2484145 RepID=UPI0014485D00 +---LAERINFLWRGFPGKTGIAVQRIDGEWAI-AERGGELFPQQSVSKLWVALTALDAVD +QGRVRLDQQVRIGPEDLTLYQPLAARVRAQGMTLRQLIETAITQSDNTANDSVLRTVGGP +GAVRAYMAKKDLGAIRFGPGERLLQSNYLANPIDGASPTAIASALTRLARGTLLSPESTE +YLLDVMSRTKSGPKRLKAGLPPGWKFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGT +TTSPIPARMALMQAVSSAVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. AG363 TaxID=2183997 RepID=A0A420CVM1_9FLAO +--DLKKTIESIISNKKADVGVSIIDPYHKERI-QINGNKLYPMLSTVKFPIALTVLNKIE +KGELSLQQKLLIKKEELLEWSPFRKEYPDGNISLEEAIKWMVSYSDNNLTDILLRLIGGP +EPVQQFINS---KDFIIRNNEEDMHKDWESQFVNKITPNETTKLLEAFNNGKILNKKHTL +WLYNAILNNTTGTKRLKGNLPQHVKTAHRTGTSFTGAVNDFGIIEISGKKKFYIAVFIHD +TYEKFGDAEAIIADISKAAYEYy +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sanguinis TaxID=33051 RepID=A0A147J645_9SPHN +--ELVSAINRLSANFSGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD +QGRARLDEPIVVRREDLTLHQPIAMLVKGDGTTVGELLTRALTQSDNTANDRLLTFVGGP +QAVRAMIANKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR +ILIDTMEASRTGHARLRAAVPAGWTIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD +TTEDIRKRQLLIQNVAAAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Taibaiella chishuiensis TaxID=1434707 RepID=A0A2P8CZH8_9BACT +-tALEQQIGQITAGKKAEIGIAIIGPAPGDQV-MIHAAPLYPMLSTFKFPVALTVLHQVE +QGKLSLNQQIFIRKEELLDWSPFKEKYPKGDITLADALTWMMCYSDNNITDILLRLIGGT +TPVQQFI---GGNDFVIRNNEEEMHANWDAQFVNRISPARAAQLLNQFQQGKLLHKKHTR +WLYKAMLGNKTGLKRLKGKLPPTVKVAHRSGTSFTGAINSFGIIELPGGKRIVIAVLIRD +TYESFDDTETIIADIAKTTYDFy +>[subseq from] Class A beta-lactamase n=1 Tax=bacterium TaxID=1869227 RepID=A0A4Q3VWV3_9BACT +--DLAQQIRAIEAQFGARLGVAAQRF-GGPRF-DYRGEERFPLQSVFKLPLAVVVLRAVD +AGKLRLDDSVTLSKANISVYSPLSERVWATGTTWADLIRASVSKSDNTAADVLMRRIGGP +TTTTANLHALGAQGLRIDRYESRLQCRALSEVRDSSTPKGMLTFLRGYETAGWLSTRSKE +FLDRALFETTTGPDRLKAGFGPGWKLRHKTGTGGYGARNDVGIATDKVGSKVAIAVFFSG +AVGSDKTRDAAIAKVARLVR--- +>[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Muricauda pacifica TaxID=1080225 RepID=A0A2T0MBA4_9FLAO +--RLKQEIEQVVEGKLATVAVSIQGMEPQETL-SVNGNLHLPMQSVFKLHLAAAVLNEID +KGKLGINDSIKLTPELILEWSPLRKKYPKGGVQIEELLKYNVAWSDNVGCDVLLDLIGGP +IAVQNYIHGLGVKDIAIIDKEIFLQSDWSRQYLNWSTTNASNSLLQILYEQNILSASSHQ +FLMATLKETSTGKGKIRGQLPKDAVVAHKTGSSGTGATNDIGIVFLPDNRYFYISIFVSD +SKEDEVTNQKMMADITKLAWDYf +>[subseq from] Serine hydrolase n=1 Tax=Sporanaerobacter sp. JN28 TaxID=2507161 RepID=A0A410QCW4_9FIRM +---LENKIREFIKNQKGNVAVAIKDLKTGKEI-KINENLVFPSASTIKLSIMSELFNRVN +MRSLNLNDKIKLTENMKTGGDGILKEELGHKFTLKEIMTLMIIISDNMATNILIDLL-GM +DNINKRIKDMGLKNTRLQRKMMDSQAA-KEGRENLTTANDLCLILELIYRGKNINEECSR +MMLDILKRQQV-RGRLDLYLPEDVIIAHKTGDLDC-LEHDVGIVYLPHRE-YIICVLTNE +TE-TNKDGREIIGKVSKMVYDEf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Apibacter sp. HY039 TaxID=2501476 RepID=UPI000FEBEBB0 +--PLEKTINSIIKNKKATVGVAVIY-DGRDTL-TVNNNYHYPTMSVFKFHQSLAVLDYMD +KNLLPLETPLFLKKSDLRPYSPLRDERPEGNISIGELVKYTVAKSDNNTSNALFHYMSGT +RMTDLYIRTLGIKDFAITATEAEMSDDFNNQYLNWTTPLAAARLLEVFLKDDLVSKDTRD +FLVNAMVQTTTGPDKLKALLPATTKIGHKTGSSARSADNDIGFVVLPNGKQYSIAVFVMN +SMESDKTNARIIADISKAVYDFy +>[subseq from] Class A beta-lactamase n=2 Tax=unclassified Sphingomonas TaxID=196159 RepID=A0A430E140_9SPHN +---LVSAINALGGGFQGKVGIAVRSIDDGWVV-GHAMDERMPQQSVSKLWVALTVMNAVD +EGRLALTTPVTITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTMSDNTANDKLLNLAGGP +VAVRDFIASRGLGNIRFGPGERLLQAAYVSDPPDGAGAGAIADALARLHHGMLLTPQSTS +WLLDTMSHTRTGRARIRAALPAGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAIAVLIGD +TSRPVPERQQLIQTVVSSIV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Coprobacter fastidiosus NSB1 TaxID=1349822 RepID=A0A495VQ65_9BACT +-rELKMRIASVLKERKATVGIAVLY-GDNRLF-EVNRG-DYPMMSVCKFPLALAVLDYLH +KNNLSLDTEIFIRESDLLPYSPLRDRHPQGNMSIQELLSYTVSLSDNNACDILFGYIGGT +KVVDDYIKRLGISGMSVVATEAVMHESFEKQYCNTATPSSAVLLLDKFLKEDLFRDEYGN +YLRKIMIETSTGNDKIKAGLPERVVMGHKTGSSDRNGDNDLAFVQLPDGQCYCIAVFIRD +SKEDDKTNAAIIASVSKVVYDY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Gabonibacter massiliensis TaxID=1720195 RepID=UPI00073EE5AA +heNLQKQLRETIAGKNAQVGIAVI-LNGKDTI-TVNNDCQYPMMSVFKLYQALAVADYCQ +KEKLSFETSVYIRRSDLKSYSPLRDRYPQGELPIKELLKYTLHLSDNNACDILFARTGGT +EATDKYIRSLGIRDFSVEFTEDEMHKDINTCYRNWSTPLEAVKVMELLLTRPLFDKDYQD +FIKQAMVTCETGKDRLPFPLETEAIIGHKTGTGDKGGINDVGFVYLPNGKRYTIAVFIKD +SAENMQESSRIIADISRVVYQY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingosinicella sp. GL-C-18 TaxID=2116704 RepID=A0A2P7QJJ8_9SPHN +------------------------------------------------------------ +------------------------------GVSARTLMDQMITRSDNRATDLLIAELGGP +QVIDNWMRSHGLSGIRVDRTIAQLLSARRRDVRDSSTPTAMLSLLRTVDGPRALTPASRS +LLLDMMSRCHTGRNRMRALLPAGTRVEHKTGTLN-GYTGDVGFVTLPDGRRIAVALFARG +GV----NRPAVIATAARTIYDAf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A223ZX98_SHISO +------------------------------------------------------------ +-----LNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGT----------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Agromyces sp. MMS17-SY077 TaxID=2662446 RepID=UPI001326E91C +--RMTRDIAAIERRTGVTIGVAMSGAARRDSF-AYRATETFPMCSLFKVLAAAALIEARA +CDEEYWTTPQPVG--TVVEDSQVFEGLTEA--TPELAADAALRFSDNTAGNYLLRELGGP +AAIGAFAARFGARSTRLDRWEPELNEATPGDPRDTTTPADIARVYRALVLEDAAGVLVGS +RLRAWMLRNRTSDARMRAGLDRPYDLADKTGGGSYGVVNDAGVLWRPGESTRTIAILTRR +TDPEAPRDNTVVAEVTRILT--- +>[subseq from] Beta-lactamase n=1 Tax=Alistipes inops TaxID=1501391 RepID=A0A0B0BZC1_9BACT +-tELEQALRTLVERKRAETGIAVI-LNGTDTV-TVNDAGRYPMMSVFKFHQALAVADFLD +RNGLPLSTPLPIRESDLLPYSPLRDAYPQGGMSIGELLVYTLQLSDNNACDLLFRYIGGP +TAADRYIRTLGIEGFAVEATEEEMHRDLTACYRNWSHPLDAARLLEMLITRPLFRDASQE +FIIRTMTGCNTGPERLPKPLATGAVIGHKTGSGDRNGTNDIGFVQLPDGRHYTIAVFVKD +SQESLQETERIIAEASDIVYRY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas desiccabilis TaxID=429134 RepID=A0A4Q2IR14_9SPHN +--DLTRAITTLLANFNGTAAAAVTSIDQGWTV-AYNGNRPMPQQSVSKLWVAMTALDLLD +QGKLTLEDPVVVRREDLTLHQPIASLVKGDGTTVRELMRRALTMSDNTANDRLLTYVGGP +DAVRAFLTRRGIQNIRFGPGERLLQSAYVANPPDGAGATAIAEALMRLKQGKLLSPGSTR +HMLDTMAASRTGRARLHAALPPGWTLAHKTGTGQNAGFNDVGILTAPDGRSYAVAVLIGD +TTAPMRQRQELIQQVVHALV--- +>[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. B34 TaxID=95563 RepID=UPI0005B2B01C +------------------------------------------------------------ +----------------------------GPGISVANLCAATLIWSDNTAANLFLADLGRP +EALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRVLLGTVLSPASRA +RLEAWMVACETGRKRLRAGLPPGWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTE +STASPDTCAAAYAEIGRLIA--- +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. 17J27-24 TaxID=2555898 RepID=A0A4Y8ZQC2_9SPHN +-rALAAQIRALGQAFNGDIGIAVRDVQTGWAT-AYDGNTYFPQQSVSKFWVALTALDKVD +QGALSLTRPVTLTKADMTLHQPIARQIGASGTNIGTLMTRALQQSDNTCNDAVLWRAGGP +EAVRAFLREKGISGIRFGPGERLLQSKYIASPMDGATPLGVVDALARLKRGELLSPASTE +RLLSIMSHTKTGPQRLKGGLAPGWQLAHKTGTGQQAGYNDIGVITAPDGHAYAIAVLIRR +TSAPLGERMAAMQKTVRATI--- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' 210A TaxID=2014529 RepID=A0A235I8J2_9NOSO +--SLKNAVQNLAATNNLTPGIFLVDLDTGNYV-DINASTSFPAASTIKVPILIAFFQDVD +AGKIRLDDMLTMQQDMVAGGSGDLQKPPGTQYAALEVVTKMITISDNTATNMLIARLGGM +DALNQRFRSWGLTTTTIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSMPSRD +LMLDILRRTQR-DTLLPSGLGTGARSYHKTGDIGT-MLADTGLIVVPTGKRYIASVMVQR +PAN-DPRAEKLISSISRAAYQEf +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus parabrevis TaxID=54914 RepID=A0A4Y3PWR2_BREPA +---WQQALDEALKDAPGVFGVAALHVETKEEA-GHLDDELFQLASAFKIPILVTLMREVE +AGRVALDQRIASQKENRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDLVIELIGGI +DKVEAHMHELGLEQIHLRHTCWQLLNSLPTRDNNVATPRDLNRLLAMIARKEILTPASCE +LMLDILRRQQF-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPDKGAIAITVLSRA +VT-EKPAAELAIARIARAIYDQ- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sanguinis TaxID=33051 RepID=UPI0009E8DF17 +--ELVSAINRLSANFSGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD +QGRARLDEPIVVRREDLTLHQPIAMLVKGDGTTVGELLTRALTQSDNTANDRLLTFVGGP +QAVRAMIANKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR +ILIDTMEASRTGHARLRAAVPAGWTIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD +TTEDIRKRQLLIQNVAAAVAD-- +>[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium rosa TaxID=76978 RepID=UPI0009FBFD2B +----------------GTLGFYLLDTATGQGF-GERMDERFAMCSSFKLSLAAHVLHLAQ +QGRIDLTQNVTYGEAFVAAHTPDTKAHLSTGMSVLDLARVSVVNSDNAAANLLLERTGGP +EALTAFWRALGDTFTRLDANEPSLNRVPLGEVRNTSTPRAMAHTVATLLTGPLLTAPHRT +LLLDWMHESATGLKRIRAGVPQGWWAGDKTGTASYDNCIDLA------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Dolichospermum circinale TaxID=109265 RepID=UPI000411439C +---LKDTLQSLATNSDLTPGVFLLDLDNGAYV-DINGNRSFPAASTIKIPILMAFFQDVD +AGKIRLDEILTLEKEMIVGGSGNIQQAPGSKYTALDLATKMITISDNTATNMLIAKLGGQ +EALNGRFRSWGLTTTMIRSPLPDLQGT------NTTSPRELGNLISMVNQGNVVTMRSRD +SMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVQR +PNND-PRAAKLISSISSSAYQYf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium 13_1_40CM_4_58_4 TaxID=1803453 RepID=A0A1Q7KMF3_9BACT +-qKLESTFDDVDQNLDGVLGVAVLDLTTGQKF-LLHADEVFPQASSIKIAVLAEFYHQAR +SGKLKLTDLYTVQSSDLVPDSYIMAGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-SM +ENVNALMDSLGLAHTRLRRKMMDLKAAG-EGRENISTPREMMTLLEDLYRGKVLNKEMTD +DFFKVLSTEKK-DSFIPRDLPEGLKVANKHGELE-GVRNDSGVVFLQNR-PYVICVMTTY +LRR-ERDGEEAISKISLTAYRIf +>[subseq from] Class A beta-lactamase n=1 Tax=Alistipes sp. 56_11 TaxID=1896968 RepID=A0A1Q6ECW9_9BACT +-tELEQALRTLVERKRAETGIAVI-LNGTDTV-TVNDAGRYPMMSVFKFHQALAVADFLD +RNGLPLSTPLPIRESDLLPYSPLRDAYPQGGMSIGELLVYTLQLSDNNACDLLFRYIGGP +TAADRYIRTLGIEGFAVEATEEEMHRDLTACYRNWSHPLDAARLLEMLITRPLFRDASQE +FIIRTMTGCNTGPERLPKPLATGAVIGHKTGSGDRNGTNDIGFVQLPDGQHYTIAVFVKD +SQESLQETERIIAEASDIVYRY- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2X3H3Y8_KLEPN +-----EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTHYPGQHG------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. HMF7854 TaxID=2315330 RepID=A0A3R9Z507_9SPHN +--DLQAQLRALAVAQPGGAGIAAIDLATGREI-SVDGDRPFPLASTVKLLVAATYLDAVD +QGRRSLAEPIPFDERWRHHGLMTVLAHPGVTLSAANWIEAMLTQSDNSAADQMFAAVGGP +AAVQRWATAHGVAGVRVDRDIGGILLRFAADPRDQGSALGMARLLARIDRGELLRPASRA +WLLDVLGRTRTGPDRIAAGLPAGARLAHKTGSLR-GVTDDVGIATLPGGRRIAIAVLASG +PASDGKARAALIAAAARAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Tannerella sp. CAG:118 TaxID=1262978 RepID=R5I3Z5_9BACT +-dELRKELETVIRDKKARVGVAVIY-DGKDTL-TLNNEYRYPMMSVFKFHQALSVLNDLD +SRGLPLDTEIFVKKSDLHPYSPLRDSVPQGNMTVAELLRYSITLSDNNACDILFKHFGGT +DRTEKYMKGLGIEKIVIQSDENEMHTSVDAERANWTTPLEAAKVMDIFLRNKLFPISLSD +FLENLLICTSTGADKIKGGLPSGVIMGHKTGSSSRTADNDLAFVQLPDGKRYTIAVFVMD +ADEDDKTIAGIISQISRHVYDFy +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. AF17-1 TaxID=2292919 RepID=A0A3A6LVQ3_9BACE +---LKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD +FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD +SKENMETNAKIISDISAAVYRY- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas guangdongensis TaxID=1141890 RepID=A0A285QGZ1_9SPHN +---LKETIGALRNQFDGLAGIAVRSVDEGWAIeSVDADRRMPQQSVSKLWVAMTVLDAVD +RGRLGLDTPVRIRREDLTLHQPIASLVKADGATVRELLQRAMTQSDNTANDSLLRTVGGP +TAVRSFITRKGLGNIRFGPGERLLQARYVADPVDGAAPAAIAAALARLKRGDVLSSTSTD +YLIRTMESSKTGKYRLRGAVPPGWTFGHKTGTGQTAGYNDVGLLTAPDGRTYALAVMIGD +TRRPIQERQLLMQAVVAAIVA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. FARSPH TaxID=2219696 RepID=A0A345WNN2_9SPHN +--QLVERIDRLAAGFDGKFGIAIRAVDEGWTVaSPGARTRMPQQSVSKLWVAMTLLDLRD +QGKARLDDPIVVRREDLTLHQPIAMLVKGDGTTVGELLRRALTMSDNTANDRLLTYVGGP +AAVRAMIERKQLGDIRFGPGERLLQAAYVNDPPDGAAPLAIADALARLARGELFTETSTR +ILLDTMGASITGRARLRSALPAGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +SRRPIRERQELIAGVAAAVADY- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-CE-1G-424 TaxID=2135658 RepID=A0A4R2RXL6_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIIRSDNQATDQLLAALGGP +GAIQQWLSSQNITGIRMDRTIAQLLRGHLADSRDVATPVAMVTLLNKIDNGTVLTAQSRT +FLLELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG +GR----DRQPVIAQVARAIYDRf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. PAMC28499 TaxID=2565554 RepID=A0A4V1CFY5_9SPHN +--HLLAEFDRFAALSDGTVGLAVQDLQTGEVQ-SRNGDTLFPMASAYKVAVAGRILSLVD +AGSLKLDDRLVLDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP +KAVSDFVAGLGIHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLVAYESGKALKPESTQ +LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK +DSRGHVSRDQIMAQAARAAYDYf +>[subseq from] serine hydrolase n=1 Tax=Porphyrobacter algicida TaxID=1836209 RepID=UPI001325DC20 +-tDLERRVASVADGSNGRIGVAAVDLSTGQMV-SVLGDQRFPMASTSKIAIAATFMQGVE +DGRWSLNDSFPMLYPVRSKSSKVAPVREGERLPATRLIELMITRSNNYAADALLRVVGGP +EAVDKWVHRAGISNFNMTRDILTLVRANHIDNRDSATPKAMVTLLAGLYQGRWLSADSRK +VILGAMSRTVTGRNRMKYLIPTDAKVLHKTGSLHD-TCSDVGLIETPDGRTLAVAVYVTG +QR-SRGAREQKIAMISRAIYDGy +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. PP-F2F-A104-K0414 TaxID=2135661 RepID=A0A4R2TAS4_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMDLMIIRSDNQATDQLLAALGGP +AAIQQWLLSLQIPGIRMDRTIAQLLRGHLADSKDVATPVAMVTLLNKLDNGSVLTAQSRN +FLFELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG +GR----DRQPVIAEVARVIYDRf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. YJ09 TaxID=1104779 RepID=UPI0012D35C5A +--HLANRIDELGRGFSGRVGIAVKSIDDGWET-GWRDNDLYPQQSVSKLWVSITALDAAD +RGRIDLDDKVTLTRSDLTLHQPIAAEVLDDGTTLGDLMKRAITTSDNTANDRLMRAVGGA +SAVRAMIARKGLGSIRFANGERDMQSRYIADPYDGAAPSAIVDALASLKRGELLSRASTE +RLLDIMGHTRTGPNRLKGGLQPGWTLSHKTGTGQQAGYNDIGILTAPDGRSYAVAVMIKK +TSTPLRVRMTLMNNVVEAVIEQ- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. LK11 TaxID=1390395 RepID=UPI0009FA5D23 +--ELVSTINRLSASFAGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD +RGRARLDEPIVVRREDLTVHQPIAMLVKGDGTTVGELLNRALTMSDNTANDRLLTYVGGP +QAVRAMIAAKRLGDIRFGPGERLLQAAYVSDPPDGAAPIAIADALARLARGELLSETSTR +ILIDTMEASRTGHARLRAAVPSGWQIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD +TTEDIRKRQQLIQNVAAAVAN-- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides cellulosilyticus TaxID=246787 RepID=A0A6A1IUX0_9BACE +-qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKYHVGLTVLDKMD +KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI +DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNITDKQILFGTQYKD +FLQATMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQETDADNAAIIASISKIVYDT- +>[subseq from] Uncharacterized protein n=1 Tax=Chlorogloeopsis fritschii PCC 6912 TaxID=211165 RepID=A0A3S0ZXD9_CHLFR +-----TAVQSLVADNNLTPGVFVVDLDNGGYV-DVNASSSFPAASTIKIPILVAFFQDVD +SGKIRLDESLTMQKEMVVGGSGDMRKPVGTQFTALEVATKMMTISDNTATNMLITRMGGI +EALNQRFRSWGLTITTIRNPLPDLQGT------NTTSPKELGNLMAMVNQGNLVGMISRD +RILDIMRKTVR-NHLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTNKRYIVAVMVKR +PNND-PRAEKLISSISRAAYQQ- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas melonis TaxID=152682 RepID=A0A0D1KQC9_9SPHN +--RLTAAIDSLARNFDGKFGIAIRAVDDGWTVtSPGARTRMPQQSVSKLWVAMTLMDLRD +QGKARLDDPIVVREQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP +QAVRAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALARLARGELFSETSTR +ILLDTMGASVTGRARLRAAIPAGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +SRRPIRERQQLIQAVAAAVAN-- +>[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas sp. Root1423 TaxID=1736462 RepID=UPI0009E73E23 +-----AALEALADQTPGTLAACVVD-EAGASC--VNGDRPSSMQSVMKLLVGLAVLDAVE +RGELGLEDRVTLTRADVSVVQPIESRLGPSGTTIGELVRGAVIQSDSMATDWLIARLGGP +GAVQAFLERKGVTGIRLDRDERHLQTAYQQDVRDTATPRAMATLLYRLASGDLLGTSSTR +WMLATMKETQTFPDRLRAGTAPGWDAAHKTGTSNTGATNDVGVLTSPLGEPSGVAVFLAN +SPAEAPARAAAIAKVARIVTR-- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=2 Tax=Sphingorhabdus sp. SMR4y TaxID=2584094 RepID=A0A220WB64_9SPHN +--ALVREIDQLWRTFPGKTGIAIKRIDGEWEF-GHRIDEYFPQQSVSKLWVAMAMLDKID +KGRASLSDPIRITKDDLTLHQPMAVEVEREGKSVYTLLEKALASSDNTANDALLRHAGGP +EAVRRFIDENDLGKIRFGPGERLLQAAYLADPVDGASPRAIVRALDKLARGELLSPNSTK +LLQSILKRTRSGPNRLKAGVPAGWEFLHKTGTGQATGYNDIGIMTAPDGTRYAVVVMLGD +TTASIPERMRMMQAVTRAVGR-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SGJ3_9BACT +--PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD +KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT +SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK +FLENTMIVTSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD +SMEDDKTNAAIIAQISKAVYDY- +>[subseq from] serine hydrolase n=1 Tax=Dolichospermum circinale TaxID=109265 RepID=UPI0004243CE6 +---LKDTLQSLATNSDLTPGVFLLDLDNGAYV-DINGNRSFPAASTIKIPILMAFFQDVD +AGKIRLDEILTLEKEMIVGGSGNIQQAPGSKYTALDLATKMITISDNTATNMLIAKLGGQ +EALNGRFRSWGLTTTMIRSPLPDLQGT------NTTSPRELGNLISMVNQGNVVTMRSRD +SMLNIMNRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVQR +PNND-PRAAKLISSISSSAYQYf +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Sphingomonas sanguinis TaxID=33051 RepID=A0A147IJI9_9SPHN +--ELVSAINRLSANFSGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD +RGRARLDEPIVVRREDLTLHQPIAMLVKGDGTTVGELLTRALTQSDNTANDRLLTFVGGP +QAVRAMIANKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR +ILIDTMEASRTGHARLRAAVPSGWTIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD +TTEDIRKRQLLIQNVAAAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia anophelis 502 TaxID=1355388 RepID=T0PV66_9FLAO +---LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVFHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLVGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNNAHTQ +WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRATWNYy +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5ZYJ5_9BACT +------------------------------------------------------------ +-------------------------------MTLGALCAAAIEQSDNTAGNLLLDTIGGP +VGLTNFARSVSDETTRLDRKEPELNSAIPGDERDTTTPAAMCADMQRFLLGNVLSESSQN +QLQDWLRQNETGSLMIRASVPKTWTVGDKTGRCGNGATNDVAIIGPPGRAPILVAIYSIG +STSSADDRAAIVAEPARAVVE-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas echinoides TaxID=59803 RepID=UPI00026CDB2B +--ALVANVAALVRAFDGRVGVAVRSIEEGWAV-DTGGEQRLPQQSVSKLWVAMTVLDFRD +AGRLKLEDPITLTRDDLTVHQPIAALIKGEQTTVGELLQRALTMSDNTANDRLLRYVGGP +NAVRDFLQRKRLGDIRFGPGERLLQSRYVADPPDGAAPRAIADALARLKRGDLLSRSSTE +YLLTTMESSHTGKQRLRGAVPAGWTFGHKTGTGQTAGYNDVGLLIAPDGRSYAIAVMIGD +TPKPIPARQALMQAVVASVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides dorei TaxID=357276 RepID=A0A5C6LAI9_9BACE +-kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITATEDEMHQGMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD +FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD +SKENMETNAKIISDISAAVYRY- +>[subseq from] VEB-PER n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SEL0_9BACT +------------------------------------------MQSTYKFHLALAVLGKLD +KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNLTTPDATIQLLKKFYKNEILSKNSYD +FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf9 TaxID=1735674 RepID=A0A0Q4CJ24_9SPHN +--ALVAAINALGDGFQGRVGIAVRSIDDGWVV-GHAMDQRMPQQSVSKLWVALTTMNAID +EGRYALDTPVTITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTMSDNTANDKLLNLAGGP +IAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAVADALARLHHGMLLSPTSTR +WLLDTMSHTRTGRARIRAALPAGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD +TSRPVQERQQLIQTVVSSIV--- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A1H7III0_BACVU +-kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITATEDEMHQGMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD +FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD +SKENMETNAKIISDISAAVYRY- +>[subseq from] Uncharacterized protein n=1 Tax=Parasitella parasitica TaxID=35722 RepID=A0A0B7NNL7_9FUNG +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMP---------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Sanguibacteroides justesenii TaxID=1547597 RepID=A0A0C3NCP8_9PORP +heNLQKRLRETIAGKNAQVGIAVI-LNGKDTI-TVNNDCQYPMMSVFKLYQALAVADYCQ +KEKLSFETSVYIRRSDLKSYSPLRDRYPQGELPIKELLKYTLHLSDNNACDILFARTGGT +EATDKYIRSLGIRDFSVEFTEDEMHKDINTCYRNWSTPLEAVKVMELLLTRPLFDKDYQD +FIKQAMVTCETGKDRLPFPLETEAIIGHKTGTGDKGGINDVGFVYLPNGKRYTIAVFIKD +SAENMQESSRIIADISRVVYQY- +>[subseq from] serine hydrolase n=1 Tax=Sphingosinicella sp. CPCC 101087 TaxID=2497754 RepID=UPI00101E0020 +------------------------------------------------------------ +------------------------------GATASSLLDSMITRSNNRATDLLMASLGGP +GAIDRWLRAHRLTGIRVDRTIAQLLSDRRRDIRDSSTPAAMIDLLRLIDSGDALSPSSRS +LLLDMMRRCATGSNRIRGLLPPSVQVAHKTGTLN-GYTGDVGFVTLPDGRRIAVVFFARG +GT----NRPAVISTAARAVYDTf +>[subseq from] class A beta-lactamase n=1 Tax=Rhodanobacter thiooxydans TaxID=416169 RepID=UPI0009D98406 +---LQMRLDALAQRAPGTLGIAVLDLRSGEAW-RVNARQAFPMMSVFKAPVAGAVLDRIE +HGGLSMELTVVIRRRELSSGT-IRDHFEGERFTVRQLLADAVSRSDNTAVDALLDTIGGP +RVVTAFLRSRGIDGMRVDLGERDFQSAYLVDPRNRSTPDAAAQFLRKLWEGQLLPPEPTR +HLLDLMYAQTT-PSRLRLGLPPGARLADKCGTSYTAAYNDIGILSWPDGHAIVVAAFLTA +SVDPKGERDALFADLARTVAA-- +>[subseq from] Beta-lactamase n=2 Tax=Nostoc cycadae TaxID=246795 RepID=A0A2H6LGL0_9NOSO +--SLKNNIQNLAATTDLTPGIFLVDLDNGGYV-DINASVGFPAASTIKVPILVAFFQDVD +AGKIRLDEMLTMQQDVVAGGSGNFQKPVGTQYSALEVATKMITISDNTATNMLIARLGGI +EALNQRFRSWGLTTTSIKNQLPDLQGT------NITSPRELGNLMAMVNQGNFVSLRSRD +IMLDIMRRTER-DNLLPSGLGSGARIYHKTGDIGT-MLADTGLVDIPNGKRYIISVMVKR +PNND-PRAEKFISSISRTAYE-- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI0009EB2DBB +--ALTTTIDALARDFGGVVGISVRSLEWGWQV-DANGDRRMPQQSVSKLWVAMTVLDARD +KGRLTLDDPVELTREHLTLHQPIATLVVRDGTTVRELLLRAMQQSDNTANDRLLNLVGGP +QAVRAFIADRGLGEIRFGPGERLLQASYVADPVDGAAPSAIALALARLKAGELLSASSTN +FLTTVMSGTRTGKARLRAAVPMGWTLAHKTGTGQTAGFNDIGILTAPDGKAYSVAVMIGD +TPRPVRERQALMQAVVASVVA-- +>[subseq from] Beta-lactamase family protein n=1 Tax=Sphingomonas sp. RIT328 TaxID=1470591 RepID=A0A031HQM0_9SPHN +--QLTSAIDALARDFDGKFGIAIRAVDGGWTVtSPGARTRLPQQSVSKLWVAMTLMDLRD +QGKARLDDPVVVRPEDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP +AAVRAMIERKRLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALSRLARGELFSETSTR +ILLDTMAASVTGRARLRAALPAGWQIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +SRRPIQERQRLIQSVAAAVAM-- +>[subseq from] serine hydrolase n=1 Tax=Sphingopyxis panaciterrae TaxID=363841 RepID=UPI001423F52C +---LSDRIAGLWRAFPGKTGIAVQRIDGEWAF-SERGDELFPQQSVSKLWVTMTVLDAVD +QGRLRLDQMVRIGPDDLAVHQPLAGRVLAEGMSVRDLIETAITHSDNLANDSLLRTVGGP +DAVRRFVAKKDLGSIRFGPGERLLQSNYLANPVDGASPAAIASALTRLARGTLLSPESTE +YLLGVMSRTKSGPKRLKAGLPPGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGS +TTSPIPARMSLMQAVSGAVAE-- +>[subseq from] Beta-lactamase n=1 Tax=hydrothermal vent metagenome TaxID=652676 RepID=A0A160TNA0_9ZZZZ +--ALVANVTALGRNFNGRVGIAVRSIDQGWTV-SSNGDARLPQQSVSKLWVAMTVLDYRD +SGRLTLDDPITLTKDDFTLHQPIAALVKDGGTTIGELLRRALTMSDNTCNDRLLRYVGGP +AAVRDFIRRKGLGDIRFGPGEKLLQSRYVADPPDGAAPSAIAGALAKLKLGQLLSRQSTD +YLISTMESSKTGRQRMHGAVPAGWDFGHKTGTGQTAGYNDVGLLMAPDGRSYAVAIMIGD +TPRAIPERQALMQAVVTAVVA-- +>[subseq from] Beta-lactamase FAR-1 n=1 Tax=bacterium YEK0313 TaxID=1522316 RepID=A0A0A1PA92_9BACT +------------------------------------------------------------ +------------------PSSPITAPRAGAPLTVAEICEAAIVVSDNTAGNLLIEICGGP +ARLTRFIRTLGDSVTRLDRKLPELIVVAPDDPRDTTSPAAMGQNIHRLLLGDVLRPTSRA +QLTAWLVACRTGEARIRAGLPHGWRVGDKTGAGLAGETSDVGIIWPPGRPPVILSIYYVK +KDASGEARSAVIAEAAGLVA--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas yabuuchiae TaxID=172044 RepID=A0A147IRD3_9SPHN +--ELVSTINRLSASFAGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD +RGRARLDEPIVVRREDLTLHQPIAMLVKGDGTTVGELLTRALTQSDNTANDRLLTYVGGP +QAVRAMIANKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELMSETSTR +ILIDTMEASRTGHARLRAAVPSGWTIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD +TTEDIRKRQQLIQNVAAAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. TaxID=1883446 RepID=A0A522H1E8_9GAMM +--ELQHSLNALAQRAPGVLGVDVLDLRSGIEV-QVNAHRAYPMMSVFKAPLAAAILSQID +SGQLASGQKVILKRADVVAGSAVPSIFHGEQFTVEQLLTATVSQSDNTAADALVKLAGGP +QAVTAFLRAHGIKGMRVDLDEAGLGRAFLGDPRNRSTPLAAVAFLRKLHNHELLSPTSTR +HLLRLLQAQTV-PRRLRAGLSSDIQLADKCGTSYTAAYNDIGILTWPDGHTVIVAAFLMG +SRASRAQRDALFADLARSIA--- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. L-1-4w-11 TaxID=2572576 RepID=A0A4U1L5U9_9SPHN +------GIDAMVREFGGKVGVAIKSIDHGWMV-AKNGDDPMPQQSVSKLWVTMTLLDQVD +QGRVRLSDPITVTRADLTLHQPVASLLKNGVTTVGDLMRRAMTMSDNTANDRLLRHVGGP +AAVNAYIEKHNLGSIKFGPGERLLQSAYVADPIDGASAGAIANALTRLKRGELLSRASTA +HLIATMESSRTGRARLRATVPAGWRLGHKTGTGQTAGFNDVGILTAPDGKSYAIAVLIGD +TSRPVPARQELMQAVVASVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas spermidinifaciens TaxID=1141889 RepID=A0A2A4B943_9SPHN +-----TDIDRLVAGFGGKVGVAVKSIDAGWMV-SKNGDVPMPQQSVSKLWVTLTLLDQVD +QGRVRLDDPITITRSDLTLHQPIASLLKNGVTTVRELMRRAMTMSDNTANDRLLRHVGGP +SAVNAYIARHSLGAIKFGPGERLLQSSYVANPIDGAAAAAIANALTKLRRGELLSPASTA +YLIGVMESSRTGHARLRASVPPGWRLAHKTGTGQTAGFNDVGILTAPDGRAYSIAVMIGD +TSRPTQERQKLMQNVVARVVAY- +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia ursingii TaxID=1756150 RepID=UPI0007518BFA +---LKKTLESIISGKKATVGISVIGPDTKEVT-GINGDQMMPMLSTVKFPLALTVLHEVE +KGKLSMAQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQKFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNVKILNKAHTQ +WLYDAMLNNVSGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHD +TYESFEASEKIISDIGRATYDYy +>[subseq from] serine hydrolase n=1 Tax=Nostoc sp. UIC 10630 TaxID=2100146 RepID=UPI0013CF6421 +---LKNAVQNLAANYNLAPGIFLVDLDTGNYV-DVNGSTSFPAASTIKVPILLAFFQDVD +AGKIRLDEMLTMQQDMVAGGSGDMGSKPAGTYNALEVVTKMITISDNTATNMLIARLGGM +EALNQRFRTWGLTTTTIRNSLPDLQGT------NTTSPKELANLMAIVSQGNLVSMPSRD +LMLDILRRTQR-DTLLPSGLGTGARAFHKTGDIST-MLADTGLIVVPTGKRYIATVMVQR +PEN-DPRAEKLISSISRAAYQEf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Leaf34 TaxID=1736216 RepID=A0A0Q4KXC5_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMALMIIRSDNQATDQLLAALGGP +VAVQQWLSSHNIPGIRMDRTIAQLLRGHLADSRDVSTPVAMVTLLNKLDNGTVLTAQSRA +LLLDLMGRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG +GR----DRQPVIAEVARVIYDRf +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus formosus TaxID=54913 RepID=A0A4Y4I4W7_9BACL +---WQQAVENELKEAPGIFGIAAVHLETGETA-GHLDEELFQLASTFKIPIMVTLMREVE +AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI +DKVNEHMHELGLSQIHLPHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE +LMQDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVNT-VVNDAGIIYLPEGKGMIAITALSR +GVTDKEAAELTIARVAKAIYE-- +>[subseq from] Beta-lactamase n=1 Tax=Oscillatoria nigro-viridis PCC 7112 TaxID=179408 RepID=K9VLS5_9CYAN +---LKTQVQVLATENSLTAGIFLVDLDTGSYL-NFNGDTAFASASTIKVPILVAFFQAVD +EGKVQLDQMLTLKPEHIVGGSGEMQDSPGKKYSALEVAQKMIVVSDNTATNMMIELLGGA +EVLNQHFANWGLSTTVLRNKLPDLEGT------NTTSPKDLINIIAQVDRGNLVSVKSRD +RILQIMRQTRN-DSLLPKGLGEGSVIAHKTGNINT-MLADAGMVDLPNGKRYLVAVMVKH +PPETEKPAQALIREISRMSYRY- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus parabrevis TaxID=54914 RepID=A0A656ZTK9_BREPA +---WQKALEEALKDAPGVFGVAALHVETGEEA-GHLDDELFQLASAFKIPILVTLMREVE +EGRVALDQRIASQKENRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDLVIELIGGI +DKVEAHMHELGLEQIYLRHTCWQLLNSAPTRDNNVATPRDLNRLLAMIERKEILTPSSCE +LMLDILRRQQF-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGGAIAITVLSRA +VT-EKPAAELAIARIARAIYDQ- +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000739969C +---LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGH +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDESEKIISDIGRAAYDYy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KKF6_9BACT +--PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD +KQGLPLETELFISKPDLHPYGPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT +SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK +FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD +SMEDDKTNAAIIAQISKAVYDY- +>[subseq from] serine hydrolase n=1 Tax=Calothrix rhizosoleniae TaxID=888997 RepID=UPI000B49DB16 +-----------TKNTNLTPGIFLVDLDNGTYV-DINAAASFPAASTIKTPILVAFFQDVD +AGKIRLDEMLIMEQGMIAGGSGNMKKQPGTQFTALEVATKMMTISDNTATNMLIERMGGM +EILNQRFRSWGLRTTAIRNPLPDVEGT------NTTSPKELATLMAMVSKGNLVSMRSRD +RILDIMRRNTR-NHLLPVGLGKGAIIAHKTGNIGS-MLADAGLVDLPTGKRYLAAVMVQR +PRND-PSAAALIQSISRAAYQQf +>[subseq from] Beta-lactamase n=1 Tax=Novosphingobium kunmingense TaxID=1211806 RepID=A0A2N0HJX2_9SPHN +--SLEATVAALANAGQGRIGVAATDLGTGRTV-SVLGSQPFPMASTSKLAIVATFLQGVD +QGRFSLSDRYPLMVPVPSASSTVAPVRAGATMTAWQLIDRTIINSDNQATDALLRVVGGP +AAVNKWVREAGLTGFSLNRDIATLVRARVVDQRDAATPLTMVQLLTGLHQGRWLSQSSTG +VILSAMERCVTGKRRLKALLPGEARVLHKTGTLSN-TSSDVGIIKTPDGRDIAVAIYVTG +QGG-KSFRDSRIASIARAIYDGy +>[subseq from] Class A beta-lactamase n=1 Tax=Blastomonas sp. TaxID=1909299 RepID=A0A2D6H2E6_9SPHN +--GLRDELQELWRTFPGKTGIAVRRIDGDWVI-GQRGGELFPQQSVSKLWVTMTVLEKVD +RGEVSLDQEVTITANDLTLHQPLAARVSREGETVRSLINEALTASDNSANDALLRTAGGP +GAVQDFLRRKGLANIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQSSTR +LMLETLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLAE +TTASIPARMQLMQAVSRAV---- +>[subseq from] Serine hydrolase n=1 Tax=Tychonema bourrellyi FEM_GT703 TaxID=2040638 RepID=A0A2G4EZV0_9CYAN +--ALKTQVQALATENTLTAGIFLVDLDSGSYL-NFNGDTTFASASTIKVPILVAFFQAVD +DGKVRLDQTLTLRAEDIVGGSGEMQDAPGKKYSALEIARKMIVVSDNTATNMMIDLLGGA +EVLNQHFATWGLRATVLNNKLPDLEGT------NTTSPKDLINIIAQIDRGNLVSVKSRD +RIFQIMQQTKN-DSLLPKGLGAEAIIAHKTGNINT-LLADAGMVDLPNGKRYLVAVMVKH +PPETEKPAQSLIRDISRMSYRY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingorhabdus sp. GY_G TaxID=2292257 RepID=A0A371B2E9_9SPHN +--QLEAELHEIWRAFPGKTGIAVQRIDGQWVT-GKRLGEWFPQQSVSKMWVAMTILDQVD +SGRLRLDQTVRIGMNDLAVHQPIRERVVANGESISSLLEQAITASDNTANDSLLRTAGGP +AAVRNFIERKQLGKIRFGPGERLLQSAYLADPIDGAAPDAIAGALSRLARGELLSPASTR +LLLAMMERTKSGPNRLKSGVPAGWRFGHKTGTGQSTGYNDIGIMTAPDGTRYAVVVMISS +TTAPVPDRMAMMQAVSRTVAAH- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Microcoleaceae TaxID=2053578 RepID=A0A355CDE5_9CYAN +----KPQIEQAIEQYSLSAGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFYQDVD +AGKVSLNETLVMKSDLVASGSGTMQDEADGTFSIRETVDKMITISDNTATNMIIERLGGI +AKLNERFRSWGLTDTIIRNWLGDFQGT------NTTSSVDMVQLLAMLSRDKLVSESSRE +QVLELLRHTTT-RTLLPSGLGAGAVIADKTGDIGF-VVGDAGIIDMPNGKRYLAAIFVKR +PYND-PIVRDFVRRISRIVYNY- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc punctiforme NIES-2108 TaxID=1356359 RepID=A0A367S0K8_NOSPU +--SLKNAVQNLAATNNLTPGIFLVDLDTGNYV-DINGSTSFPAASTIKVPILIAFFQDVD +AGKIRLDDMLTMQQDMVAGGSGDLQKPPGTQYAALEVVTKMITISDNTATNMLIARLGGI +DALNQRFRSWGLTATTIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSMPSRD +FMLDILRRTQR-DTLLPSGLGTGAKAYHKTGDIGT-MLADTGLIVVPTGKRYIASVMVQR +PAN-DPRAEKLISSISRAAYQEf +>[subseq from] Beta-lactamase class A n=1 Tax=Erythrobacter nanhaisediminis TaxID=604088 RepID=A0A1I5MTX6_9SPHN +--MLEARLQQIGEGFAGEVGIAAVEVTSGATM-AYNGDRPFPQQSVSKLWVSLTALDLVD +EGALDLSEPVAIRRGDLTVYQPIRDIVRTRGTDYRDLMERALTQSDNTANDRLLRRVGGT +QAVEAFMRRKGIEGVQFGTDERSKQSDYLDDPIDGASASGMAQALARLARGELLSSRSTE +FILSTLENTKSGPRRLKGGVPSGWSIAHKTGTGQHSGYNDVGVLTAPDGTQYSLAVMIAR +TRTSYAARFEMMQSVTRSVVEY- +>[subseq from] Serine hydrolase n=1 Tax=Calothrix elsteri CCALA 953 TaxID=987040 RepID=A0A2A2TAB0_9CYAN +--TLRTSIQSITAANSLTPGVFIADLDNGSYV-DFNGGAMFSAASTIKIPIIVAFFQDVD +AGKIRLDETITSTKSAIATGSGDIQYKPAGTYTALEVVTKMITISDNTATNMLIERLGGI +ETLNQRFRSWGLNTTTIRNILPDIEGT------NTTSPKELANLIAVMTKGNLVSMQSRD +RILDIMRRTVK-DNLLPSGLGQGATIAHKTGEIG-AILADAGLVDLPTGKRYIAAVIVQR +PRND-AGAEKLISSISRAAYQQf +>[subseq from] Class A beta-lactamase n=1 Tax=Dysgonomonas sp. 37-18 TaxID=1895907 RepID=A0A1M3LBR2_9BACT +---LRNKIQKIIQGKDATVGVALI-VDGKDTL-TINNNFRYPTQSVYKFHLALAVLDYLN +KNNLTLDHQLYVKKGDLLPHSPLRDDYPQGELSVADIIRYTVSKSDNNGCDILFRLVGGT +AVVDRYIRGLGLSEFAITATEEEMHGPWEVQYTNWSTPYTAAQALEIFRTQDILPQPFHD +FLWDTLAGTTTGGNKIKALFPEGTFVAHKTGSSFRNAENDIAIIQLPDGRYYSLVVFVAD +SMESNDVNCGIIAQISKAVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Chroogloeocystis siderophila 5.2 s.c.1 TaxID=247279 RepID=A0A1U7HP50_9CHRO +--SLKTTVEQLAAQKNLLPGVFFLDLDTGAYL-EINGNSTFASASMIKVPVLVAFFQDVD +AGKIRLDERLTLKKELVGGGSGDMQKPLGTKFTALETATKMITISDNTATNLLIERMGGA +AALNERFLSWGLPATQIRNLLPDLEGT------NTTSPRDLAQLMALIDDGKLMSLRSRD +RLLDIMRGTVT-NTLLPRGLGEGARIAHKTGDIGS-LVGDVGLVDMPSGKRYIAVAMVKR +PHND-GRAQELIRQISRAAYQE- +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. SDF0063 TaxID=2133753 RepID=A0A544UPL3_9BACI +---WQQAVENVLKEAPGIFGIAAMHLETGETA-GHLDEELFQLASAFKIPIMVTMMREVE +AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELIGGI +DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE +LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEEKGMIAITALSR +GVTDKESAELTIARVAKAIYE-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=UPI000E4F4A28 +-kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITATEDEMHQGMDDCYKNWTTPIEAANLLELFMTQDFMRNEYTD +FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD +SKENMETNAKIISDISAAVYRY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=T1WEK3_ECOLX +------------------------------------------------------------ +-------------------------------MSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sanguinis TaxID=33051 RepID=A0A147HWJ0_9SPHN +--ELVSAINRLSANFSGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD +RGRARLDEPIVVRREDLTLHQPIAMLVKGDGTTVGELLTRALTQSDNTANDRLLTFVGGP +QAVRAMIANKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR +ILIDTMEASRTGHARLRAAVPSGWTIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD +TTEDIRKRQLLIQNVAAAVAD-- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI0008532722 +---WQQAVENVLKEAPGIFGIAAVHLETGESA-GHLDEELFQLASAFKIPIMVTLMREVE +AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI +DKVNEHMHELGLSQIHLTHNCWELLNSMPTPDNNVATPAELNRLLIMIARKEILTESSCE +QMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR +GVTDKEAAELTIARVAKAIYE-- +>[subseq from] Uncharacterized protein n=1 Tax=Phormidium ambiguum IAM M-71 TaxID=454136 RepID=A0A1U7I3U8_9CYAN +---------------LFTPGVFAIDLETGNYA-EINGNNSIAAASTIKMPILIAFLQDVE +AGKIKWDEKLILKSEFRASGSGILRNKVGSEFTAGDVATRMITISDNTATNMVIDRLGGI +EALNRRFQEWGLSATKLQNPLPDVKGT------NTSSPKELAVLMARVMRGELLSAASRD +RMIEIMHQTEN-DNLLPKGIGEGAKIAHKTGNIGS-MLADVGIVNLPSGKRYVIAVMVQR +PRRD-VRAQKIIQQISNTTYQYf +>[subseq from] serine hydrolase n=1 Tax=Phormidium ambiguum TaxID=71191 RepID=UPI0009FEB9AE +---------------LFTPGVFAIDLETGNYA-EINGNNSIAAASTIKMPILIAFLQDVE +AGKIKWDEKLILKSEFRASGSGILRNKVGSEFTAGDVATRMITISDNTATNMVIDRLGGI +EALNRRFQEWGLSATKLQNPLPDVKGT------NTSSPKELAVLMARVMRGELLSAASRD +RMIEIMHQTEN-DNLLPKGIGEGAKIAHKTGNIGS-MLADVGIVNLPSGKRYVIAVMVQR +PRRD-VRAQKIIQQISNTTYQYf +>[subseq from] Beta-lactamase family protein n=1 Tax=Sphingobium sp. RAC03 TaxID=1843368 RepID=A0A1B3MS96_9SPHN +--RLIAQFQRFATLTDGTVGITVRDLASGESL-SLNGDTLFPMASAYKVAVAGKIFAMID +AGQLALTDIVPRDVATMG---------PGAPLPVAQLLDLMLTQSDNHATDMLVARAGGP +AAVNAWVAGLGIKGLRVDSNTADLLYAFARDPRDSATPTAMTDLVAAIRTGRALSPASTH +AFITIMERCRTGKARLPGMLPPGTTIAHKTGTIN-GTGNDTGVITLPDGRMFAITVFVMQ +DHRGRVMRDRIMAEAARAAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium CG12_big_fil_rev_8_21_14_0_65_65_10 TaxID=1974094 RepID=A0A2M7HH52_9SPHN +--ALDRRLNEIGSKFAGQVGIAVRPVESDRTM-HYRGLEPFPQQSVTKTWVALAAFRQVD +EGKLALDEPRIVRREDLTLHQPIRAEVLRKGTDYADLLDRALTRSDNTANDVILRRVGGP +DAVQGTLDKLGLGSIRFGTDERTKQSGYLADPIDGAPPVAVVAALARLAKGELLSDDSTE +RFLKILSETRSGPNRLKGGLPPGWTIAHKTGTGQQTGYNDIGLITAPDGRRYAVAVMIAR +TEQRVPERMEMMHEVVAAVVEY- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' 232 TaxID=2014531 RepID=A0A235J5T9_9NOSO +--SLKNAVQNLATTNNLTPGVFLVDLDTGNYV-DVNSSTSFPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMQQDSIAGGSGNLQYKPAGTYAALEVVTKMITISDNTATNMLIAKLGGI +EALNQRFRSWGLTTTTIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSVPSRD +LMLDILRRTEK-NTLLPSGLGTGARAYHKTGDIGT-MLADTGLIVVPTGKRYIASVMVQR +PEN-DPRAEKLISSISRAAYEEf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf34 TaxID=1736216 RepID=UPI0009EBCA19 +------------------------------------------------------------ +---------------------------------AAKVMALMIIRSDNQATDQLLAALGGP +VAVQQWLSSHNIPGIRMDRTIAQLLRGHLADSRDVSTPVAMVTLLNKLDNGTVLTAQSRA +LLLDLMGRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG +GR----DRQPVIAEVARVIYDRf +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter buctensis TaxID=1503981 RepID=UPI0013681E46 +------------------------------------------------------------ +-------------------------------LPASELIDLAITRSSNPATDALLAAVGGV +SAVNAWARRAGIEEFNLTRDIATLVRATQIDLRDSSTPEAMVELVAGIYQGRWLRPESRA +VIVRAMENCRTGTRRIPALLPAGALVAHKTGSLNN-TSSDIGIITAPDGRSIAVAIYVTG +QG-TRANREARIASIARAIYDGy +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sanguinis TaxID=33051 RepID=UPI0009EF0003 +--ELVSAINRLSANFSGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD +RGRARLDEPIVVRREDLTLHQPIAMLVKGDGTTVGELLTRALTQSDNTANDRLLTFVGGP +QAVRAMIANKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR +ILIDTMEASRTGHARLRAAVPSGWTIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD +TTEDIRKRQLLIQNVAAAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=bacterium A52C2 TaxID=1855383 RepID=A0A1H9LLM6_9BACT +--DLQAQLDALAHKAPGKFGISVLDLESGKRW-GVDAGSAYPMMSVFKAPLGATVLAQAD +AGKISLSQHVTIRRADLRTASRIAEEFRGEQFTVQELLVDAVSYSDNTAADALVRLIGGP +QVITSFLEGHGIRGLHVDIDEGGVSHAYLSDPRNRSTPDAAVAFLQTLWNGRLLPTKSTK +HLLDLLYGQTK-PSRLRAGIPAGVRLADKCGTSETAAFNDIGIMTWPDGRTVIVAAFLTG +SKASQAERNQLFADLAH------ +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides dorei TaxID=357276 RepID=UPI000E48E12E +---LKTEIRHIIKDKKATIGVALI-LDGEDTL-AVNNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKRYFKPYSPLRDKYPQGNLPISELLAYTMQLSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITTTEDEMHQDMDDCYKNRTTPMEAANLLELFMTQDSMKNEYTN +FLKHIMIECETGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGNRYVVAVFVKD +SKENMETNTKIISDISAAIYRY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A224A9A8_SHIFL +------------------------------------------------------------ +-----LNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYG------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Gloeocapsa sp. PCC 7428 TaxID=1173026 RepID=UPI0012DC1CDB +--SLKTTVEQLAAQKNLLPGVFFLDLDTGAYL-EINGNSTFASASMIKVPVLVAFFQDVD +AGKIRLDERLTLKKELVGGGSGDMQKPLGTKFTALETATKMITISDNTATNLLIERMGGA +AALNERFLSWGLPATQIRNLLPDLEGT------NTTSPRDLAHLMALVDDGKLMSLRSRD +RLLDIMRRTVT-NTLLPRGLGEGARIAHKTGDIGS-LVGDVGLVDMPSGKRYIAVAMVKR +PHND-GRAQELIRQISRAAYQE- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SX32_9BACT +--PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD +KQGLPLETELFISKPDLHPCSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT +SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK +FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD +SMEDDKTNAAIIAQISKAVYDY- +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas solaris TaxID=2529389 RepID=A0A558RD29_9SPHN +---LLSELERLGRGFDGVVGIAVRDVQAGWSV-SWNGTGRFPQQSVSKLWVALTLLDAVD +RGTLRLEDPITVRRSDLTLHQPVRAMMGPDGTSIRNLLTIAMTQSDNTANDVLLQRVGGP +SAVRAFFTRASISGIAFGPGEKLLQSRYLADPMDGAQPEGMVAALARLRKGDILSPGSTQ +VLLSIMAQSKTGPQRLKGGLGENWAFAHKTGTGQATGYNDVGLLTAPDGRTFAVAVMIAS +TRQPIWARMQLMQNVTRAVV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A649V1Q5_ECOLX +------------------------------------------------------------ +-------------------------------MSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFPLDRTEPTLNTAIPGDPRDTTSPRAMAQSLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVEGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDV------------ +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. OK281 TaxID=1881067 RepID=A0A1I5GEN1_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIIRSDNQATDQLLAALGGP +FAIQQWLSSHKIAGIRMDRTIAQLLRGHLADIKDVATPVAMVTLLEKLDNGTVLTAQSRA +FLFELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG +GR----DRQPVIAEVARVIYDRf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis X23 TaxID=1200792 RepID=A0A291BQ58_BREBE +---WQQAVENVLKEAPGIFGIAAVHLETGESA-GHLDEELFQLASAFKIPIMVTLMREVE +AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI +DKVNEHMHELGLSQIHLTHNCWELLNSLPTLDNNVATPAELNRLLIMIARKEILTESSCE +QMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR +GVTDKEAAELTIARVAKAIYE-- +>[subseq from] serine hydrolase n=1 Tax=Blastomonas sp. CCH5-A3 TaxID=1768761 RepID=UPI000826829E +--GLRDELQELWRTFPGKTGIAVRRIDGDWVI-GQRGGELFPQQSVSKLWVTMTVLEKVD +RGEVSLDQEVTITANDLTLHQPLAARVSREGETVRSLINEALTASDNSANDALLRTAGGP +GAVQDFLRHKGLANIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQSSTR +LMLETLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLAE +TTASIPARMQLMQAVSRAV---- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A415BNG6_BACVU +-kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDPMKNEYTD +FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD +SKENMETNTKIISDISTAVYRY- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. AF39-11AC TaxID=2291999 RepID=A0A415II51_9BACE +-qKIEQQIDSVLKDKKATVGVAVLA--NDEIVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KDHVGLDSLIEVKSSQLTPYSPLRDKFPDQDISLGELLKYTISKSDNNTCDILIEYAGGI +DQVNEYVKSLGIKDCNLAATETLMHTS-EDAYLNWSTPEEVVRLLNIADKHPLFAAQYKD +FLQAIMQETSTGKDKLKGQLPANVIVGHKTGSSDRTADNDAGFVILPDGQKYYIAVFVME +SQETDADNAAIIASISKIVYDT- +>[subseq from] Class A beta-lactamase n=1 Tax=Nostoc sp. 'Lobaria pulmonaria (5183) cyanobiont' TaxID=1618022 RepID=A0A2L2NZA1_9NOSO +--SLKNAVQNLAATNSLTPGVFLVDLDTGNYV-DVNGSTSFPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMQQDMVAGGSGNLQYKPAGTYAALEVVTKMITISDNTATNMLIAKLGGM +EALNQRFRTWGLTTTTIRNQLPDLEGT------NTTSPKELGNLMAIVSQGNLVSMPSRD +LMLDILRRTQK-DTLLPSGLGTGARAFHKTGDIGM-MLADTGLIVVPTGKRYIASVMVQR +PEN-DPRAEKLISSISRAAYQEf +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. Root214 TaxID=1736491 RepID=A0A0Q8S6I7_9SPHN +---LNDRIYELWRAFPGKTGIAVQRIDGEWSL-SQRGGELFPQQSVSKLWVTLTVLDAVD +QGRMTMDQRVRIGPEDLVVHQPLAARVRAERMSVRDLIETAITHSDNLANDSLLRTVGGP +AAVRAFIAKKDLGSIRFGPGERLLQANYLANPVDGASPAAIASALTRLARGTLLSPESTE +YLQGVMSRTRSGPRRLKAGLPPGWQFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGS +TTSGIPARMALMQSVSSAVAEY- +>[subseq from] Serine hydrolase n=2 Tax=Nostocales TaxID=1161 RepID=A0A1B7X2P4_APHFL +----KNSLQTLTTASDLTPGVFLLDLDNGGYV-DINGNASFPAASTIKIPILMAFFQDVD +AGKIRLDEILTLEKEMIVGGSGVQYQTPGSKYTALDLATKMITISDNTATNMLVAKLGGQ +EALNGRFRGWGLTTTMIRNPLPDLGGT------NTTSPRELGNLISMVNQGNVVSMRSRD +LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADVGLIDVPTGKRYIAAIMVQR +PNND-PRAAKLISSISSAAYEHf +>[subseq from] Beta-lactamase BlaZm n=2 Tax=Macrococcus canis TaxID=1855823 RepID=A0A4P9CIP0_9STAP +--KIKEDIKVIENKYNIQAGVYVNDLTDKQKL-SYNEELLFPYASTFKVINSALLIEKLG +--MNNLDKEVKVSERDIVLYSPIIEKYKNKNVSLKMLIEAALLYSDNTANNLIIEELGGL +KEVEKRLSALGIKGVNVNRKEVALNFYDPKKNEDTISAKNMSKVLIKMLTGDVLEYKEQI +FLIDLMKKNKTGTTLIKKGMDKKFIVGDKSAQGNYGVRNDIAVVYKKQSKPIIVVVFTKA +KNEKQQPSDTPIVEISKVI---- +>[subseq from] Beta-lactamase n=1 Tax=Sphaerospermopsis reniformis TaxID=531300 RepID=A0A480A1C1_9CYAN +--TLKSTLQNLATANSLTPGVFMVDLDTGGYV-DINASTSFPAASTIKIPILVAFFQDVD +GGKIRLDEMLTMEKEMVAGGSGNLRTPVGSKYTALDVATKMMTISDNTATNMLITRLGGQ +EVLNGRFRSWGLTTTAIRNILPDLEGT------NTTSPKELADLIAKVNQGNLVSMRSRD +LMLDIMRRTER-NTLIPSGLGEGARAYHKTGDIGT-MLGDAGLIDIPTGKRYIAAVMVKR +PHND-PAAETLISSISQAAYENf +>[subseq from] serine hydrolase n=1 Tax=Sphingorhabdus sp. IMCC1753 TaxID=2509719 RepID=UPI0013177A7F +---LENLLHEQWRQFPGKTGVAVMRIDGGDWVlGRRLDELFPQQSVSKTWVAMTILDLVD +QGKLKLDQRVRITTDDLAVHQPIRERVIANGETVLSLLEQAITASDNTANDSLLRTAGGP +QAVRAFMTRKKLSAIRFGPGERALQSRYLANPVDGASPEAIVRALGKLAKGELLSATSTR +LLLDIMSRTSSGPNRLKAGVPAGWRFLHKTGTGQSTGYNDIGIMTAPDGTRYAVAVMMGS +TTSSIPERMAFMQFVSRSVATY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. 28-63-12 TaxID=1970434 RepID=A0A258RUJ9_9SPHN +----VAAVNALRAEFDGTVGIAVRSVDKGWSV-STNGDLKLPQQSVSKLWVAMTVLDTRD +AGRLTLDDPVTITREDLTLHQPIAAMVTGDGATVGELLQRALTTSDNTANDRLLRYVGGP +EAVRAFIKRKGLGAINFGPGERVLQSSYVTNPPDGAAPAAIAGALAMLKKGELLSAQSTN +YLISTMESSRTGKQRLRGAVPSGWRFGHKTGTGQTAGYNDVGILTAPDGESYTLAVMIGD +TPRPIPERQALMQAVVSSVIAY- +>[subseq from] serine hydrolase n=1 Tax=Nostoc sp. 'Lobaria pulmonaria (5183) cyanobiont' TaxID=1618022 RepID=UPI000CF30942 +--SLKNAVQNLAATNSLTPGVFLVDLDTGNYV-DVNGSTSFPAASTIKVPILIAFFQDVD +AGKIRLDEMLTMQQDMVAGGSGNLQYKPAGTYAALEVVTKMITISDNTATNMLIAKLGGM +EALNQRFRTWGLTTTTIRNQLPDLEGT------NTTSPKELGNLMAIVSQGNLVSMPSRD +LMLDILRRTQK-DTLLPSGLGTGARAFHKTGDIGM-MLADTGLIVVPTGKRYIASVMVQR +PEN-DPRAEKLISSISRAAYQEf +>[subseq from] Putative beta-lactamase n=1 Tax=Bacteroides plebeius (strain DSM 17135 / JCM 12973 / M2) TaxID=484018 RepID=B5D1X3_BACPM +-qKLYANIHQFISQQKAEVGVAIIA-DGKDTV-TVENNRRYPLMSVFKLHQALAVGDYCK +RHQLSFDTLLTVDSTDLQPYSPLRDRYPHGGFSLKQLMEYTLHLSDNNACDILFKFTGGP +AVTDRYIRSLGINDFSIQYTEDDMHQDLNLGYENWSTPLATAEVIEALLTRTLFDKPHQE +FIKESLITCQTGTNRIVHPLQKQVTVGHKTGTGDRNAINDAGFVQLPNGHRYTLVIFVKD +SQESMEDTEAIIAQISEMVYQAf +>[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter sanguineus TaxID=198312 RepID=A0A1M7SFL7_9SPHN +--SFQQRIAELAEPSRGRIGVAAVDLATGEEI-MVLGDQLFPMASTSKIAVAAAYLEMVE +KERFSLTSEFPLLLPIRSAFSSARAPVRKGQMPAIDLIEIMITRSSNPATDALLAAVGGP +DIVNEWVRRQGIADFSINRDIATLVRATHIDSRDAATPRAMARLLAGLYRGDFLSDESRR +VLLGAMSRTVTGKRRIVAHIPAEARVSHKTGSLNN-TSSDIGLIECPDGRTIAVAIYVTG +QG-TRLAREERIAAIARALYDGf +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis bauzanensis TaxID=651663 RepID=A0A246JPI1_9SPHN +---LSERIHFLWRAFPGKTGIAVQRIDGEWAL-AERGGDLFPQQSVSKFWVALTALDAVD +QGRLRLDQQVRIGPEDLTLYQPLAARVRAQGMTVRSLIETAITQSDNTANDSLLRTIGGP +GAVRAYLSKKDLGAIRFGPGERLLQSNYLANPIDGASPTAIASALARLARGTLLSPESTE +YLLDVMSRTKSGPRRLKAGLPPGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGT +TTSPIPARMALMQAVSSAVAE-- +>[subseq from] Serine hydrolase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A2T7VP17_9SPHN +--RLTAAIDSLARNFDGKFGIAIRAVDDGWTVtSPGARTRMPQQSVSKLWVAMTLMDLRD +QGKARLDDPVVVRDQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP +QAVRAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALARLARGELFTETSTR +ILLDTMGASVTGRARLRAAVPAGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +SRRPIRERQQLIQSVAAAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Gloeocapsa sp. PCC 7428 TaxID=1173026 RepID=K9XKN1_9CHRO +--SLKTTVEQLAAQKNLLPGVFFLDLDTGAYL-EINGNSTFASASMIKVPVLVAFFQDVD +AGKIRLDERLTLKKELVGGGSGDMQKPLGTKFTALETATKMITISDNTATNLLIERMGGA +AALNERFLSWGLPATQIRNLLPDLEGT------NTTSPRDLAHLMALVDDGKLMSLRSRD +RLLDIMRRTVT-NTLLPRGLGEGARIAHKTGDIGS-LVGDVGLVDMPSGKRYIAVAMVKR +PHND-GRAQELIRQISRAAYQE- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf257 TaxID=1736309 RepID=A0A0Q4U1C5_9SPHN +-----STINRLSASFAGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD +RGRARLDEPIVVRREDLTVHQPIAMLVKGDGTTVGELLNRALTMSDNTANDRLLTYVGGP +QAVRAMIAAKRLGDIRFGPGERLLQAAYVSDPPDGAAPIAIADALARLARGELLSETSTR +ILIDTMEASRTGHARLRAAVPSGWQIAHKTGTGQNAGFNDVGLLTAPDGRRFTIAVMIGD +TTEDIRKRQQLIQNVAAAVAN-- +>[subseq from] Beta-lactamase n=1 Tax=Oxalobacter formigenes HOxBLS TaxID=556268 RepID=C3X3G5_OXAFO +-qSLQEKIGALVAGHRAHIGVTVGNAGGTERA-AIAADALFPMQSVYKFPIALSVLDRVD +RGELSLEKRIAISRSELRPWSPLRDRYRKGKIPLAEIVRTTMTDSDNNGCDILLRLAGAP +EKVTAFLRRHGVAGMTVATTERAMHGDWPIPFRNSSTPAAATRLLRLFEEKKLLKPRTHA +FLWNAMKNSGLSPERLRSSLPPQTPLIHKTGTSTQGTINDMGIIVLPDGQPVFVTVFVSH +GKEPKAVTEKMIPDIARVTWRHf +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. C-1 TaxID=262667 RepID=A0A0M8JDX2_9SPHN +---LQDRIFELWKAFPGKTGIAVQRIDGEWAL-AQRGGDLFPQQSVSKLWVTLTVLDAVD +QGRIKMDQRVRIGPEDLVVHQPLAARVRAEGMSVRDLIETAITHSDNLANDSLLRTVGGP +SAVRSFIAKKDLGSIRFGPGERMLQANYLANPVDGASPAAIASALTRLARGTLLSPESTE +YLQGVMSRTKSGPRRLKAGLPPGWQFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGS +TTAGIPARMALMQSVSSAVAEY- +>[subseq from] Serine hydrolase n=1 Tax=Caulobacter sp. Root655 TaxID=1736578 RepID=A0A0Q8FJG7_9CAUL +-eKLTVQLQQVADRAPGTLGVAIEDLSTSQII-SFNGERRFPLQGASKAPLGAAVLAEVD +ARRLKLDQVLTIEDVDLSPHSPIADVWPGRKYTVAELLERAVGDGDNTAADVLMEAVGGP +GAVTAWLQGRKVKPVDIDRYERQLQPAYLADPKDTATPLGAVRFLEALNQGELLSPASTR +RLVKVMIASPSAPGRLRAALPDGARLAHRSGTARTPAVNDIGVYRLKDGRKFAVAVFLSG +SSLNEADQDRVIADVGRIVIK-- +>[subseq from] Peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 n=2 Tax=Isosphaera pallida TaxID=128 RepID=E8R687_ISOPI +---LERRLRPLIAAHKGDVGVMVKHLGTGETF-AHRADAPMPTASLIKFPLLIEAYRRVA +TGALDLKTPVTLHDEDKVPGAGILTYHFSQGIPLRDVLRLMIVYSDNTATNLALDAV-GL +DAVNAEMARLGLKRTKFHSKVYRRDTSIDPEGSGVTTAAEMITLWERLHLKKLAEEALCD +AMLDHLLHCDD-KSMLVKELPPGTKVAQKTGAVSD-VRTAAGILYTPSG-PIAVCVLTAR +NQTPDNAAERFSARLAREVYDHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium GWF1_63_6 TaxID=1802168 RepID=A0A1G3JC16_9SPHN +--RLIAQFQRFATLTDGTVGITVRDLASGESL-SLNGDTLFPMASAYKVAVAGKIFAMID +AGQLALTDIVSRDVATMG---------PGAPLPVAQLLDLMLTRSDNNATDMLVARAGGP +SAVNAWVAALGIKGLRVDSNTADLLYAFARDPRDSATPTAMTDLIAAIRTGKALSPASTH +AFITIMERCRTGKARLSGMLPPGTTIAHKTGTIN-GTGNDTGVVTLPDGRMFAITVFVMQ +DHRGRVMRDRIMAEAARAAYDYf +>[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia ursingii TaxID=1756150 RepID=A0A1T3FE39_9FLAO +--ELLEKINTITKGKKATVAVSVLGIENDFQFsNAYGNLKMPMMSVFKFHIALAVLNQVD +RGNLALDQKILVKKSDLLEWSPIREKYPDGNLPLSEIITYIVAQSDNNGCDILLRLIGGV +KTVQKLMDVNGVKNFQVKYNEEEMSKKVQAPYANYNTTASMVKTLKAFYKGMFLSKRSTA +FLMEIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLGSGKHYAIAVFVKD +SMESEEVNCGMIAQISKVVWDA- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. 2SG TaxID=2502201 RepID=UPI0010F9AFDA +--QLTSAIDALARNFDGKFGIAIRAVDAGWTVtSPGARTRLPQQSVSKLWVAMTLMDLRD +QGKARLDDPVVVRPEDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP +AAVRAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALSRLARGELFTETSTR +ILLDTMGASVTGRARLRAALPAGWQIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +SRRPIRERQQLIQSVAAAVANY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. LPB0140 TaxID=1913578 RepID=A0A1L3JAM6_9SPHN +-----RAIAGLEAEYGGRLGVALWDASGGGYIgGHRSEERFALCSTFKLLLAAFILRQCD +IGKLSLDKKISYSQSDILSHAPETQKYISRGMTVEQLAKAAQISSDNVAANLLLPLIGGP +KGFTKLLRFFGDDVTRLDRIEPMLNFVPMGETRDTTSPSAISSTIAQIFTAGLLTDASAA +TLRQWTMATNTGPNRLRKYLDADWVAGNKTGTAYNGKFNDIALLWDKHRLHYIITAYYEA +PIPKDPKHEEILAQIGKIT---- +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroides nordii CL02T12C05 TaxID=997884 RepID=I9S0R3_9BACE +---LTKELDILLQGKQAKVGVAVV-FEGRETF-TYNNPHHYPLMSVFKFHQALAVMDYLD +TRQLPLETEIYVRKADLLPYSPLRDARPEGEISVGELLRYSISESDNNACDILLRYIGGT +GVVDKYVRTLGIEDFKIEANEEKLNEAFEYQYLNWTTPFAAVQVMEKFRTETLFRHSYKE +YLEKLMIGTVTGNDKLKAGLPREVVFGHKTGSSGRNGDNDMGFVRLPDGRQYSIAVFVTD +SREDDKTNATLISEISRKVYEYy +>[subseq from] Class A beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A1Q6G355_9BACE +---LTKELDILLQGKQAKVGVAVV-FEGRETF-TYNNPHHYPLMSVFKFHQALAVMDYLD +TRQLPLETEIYVRKADLLPYSPLRDARPEGEISVGELLRYSISESDNNACDILLRYIGGT +GVVDKYVRTLGIEDFKIEANEEKLNEAFEYQYLNWTTPFAAVQVMEKFRTETLFRHSYKE +YLEKLMIGTVTGNDKLKAGLPREVVFGHKTGSSGRNGDNDMGFVRLPDGRQYSIAVFVTD +SREDDKTNATLISEISRKVYEYy +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. HPS0048 TaxID=1078089 RepID=U6RA83_9BACE +---LTKELDILLQGKQAKVGVAVV-FEGRETF-TYNNPHHYPLMSVFKFHQALAVMDYLD +TRQLPLETEIYVRKADLLPYSPLRDARPEGEISVGELLRYSISESDNNACDILLRYIGGT +GVVDKYVRTLGIEDFKIEANEEKLNEAFEYQYLNWTTPFAAVQVMEKFRTETLFRHSYKE +YLEKLMIGTVTGNDKLKAGLPREVVFGHKTGSSGRNGDNDMGFVRLPDGRQYSIAVFVTD +SREDDKTNATLISEISRKVYEYy +>[subseq from] hypothetical protein n=1 Tax=Granulicella sp. L60 TaxID=1641866 RepID=UPI00131A8392 +---LQRRVQHLAAGFPGKVGILVRNIETGAQV-GINADDEFPMASTYKVAIMTQVFRDVE +AGRLSLTERVPLTENELRPGSGLLRYMTPGLPTIHDLVLMMITVSDNEATDLLLKRVGGG +ARVTATLQQLGIPNIRVDRPTLEIIGTLTDDPRDHASPRAMGDLLMKIFKSEVVSEKSSQ +DMLAIMQNQQL-KTRIPRYLE-DVAIASKSGTIGD-VTNDVGILYAGNQ-HIVISVYTLK +ANVQTEQAEEFIARTARETYDYf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1Y0BAT1_9BACT +------------------------------------------------------------ +---------------------------------AQQLMERMLIHSDNAATDILIRNLGGP +QAIQGWVSWHGFSNMRVDRTIAQLLRSPRWDSRDSATPMAMVQLLQRIDSGKVLKPGSKA +YLLSTMSRCMTGKNRMRALLPAGTRVEHKTGTLS-GLTSDVGFITLPDGRRIAVALFARG +GS----DRPNTIAQAARAIYDGf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dysgonomonas sp. HDW5B TaxID=2714927 RepID=UPI001407839D +-nTLRQEIQDIIQNKKATVGVAII-FDGTDTL-TVNNQYRYPTMSVYKFHQALAVLDYLD +KHNLPLEQQVYVSKSALHPYSPLRDKKPEGNMPVKELMQYSVSQSDNNTCDILFNFLGGT +TPVEQYIKGLGIQQIAITKTEKEMSEDFDNQYGNWTTPYAAVQLLEIFLQQELFASHYKN +FLLDALIQTSTGKDKIKGLLPAGTVVGHKTGMSSKAGDNDLGFIKLPNDKNLSIAVFIVN +SIENDTTNAEIIAQISKVTYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR485 TaxID=1500294 RepID=UPI00064627AF +--DLKKTIESIISNKKADVGVSIIGPDQKETI-QINGNTLYPMLSTVKFPIALTVLKKVE +KGELSLQQKLFIKKEELLEWSPFKKEHPEGNISLEEALKWIVSYSDNNISDILMRLVGGP +EPVQQLVNS---NDCIIQNNEEGMHKDWESQFVNKITPNEAIRLLTAFSNGKILNKEHSL +WLYNIMLNNTAGPKRLKGNLPPQVKVAHRTGTSFTGAINDFGIIELSDNKKIYIAVFVHD +TYEKFENAEAIIADISKATYDYy +>[subseq from] Beta-lactamase class A n=2 Tax=Rubidibacter TaxID=582491 RepID=U5D5N7_9CHRO +--SLQNQFSELAAQSGLEPGAFFYDLDTGEYV-NFNGDRAFSAASTIKVPVLVAFFQALD +RGEVQLDELLTMTPDLIGGGSGAMQYAPGTQFTALETATQTIVISDNTATNMLIHRLGGA +DVLNAQFQDWGLTETAIRNPLPDLDGT------NTTSPQDMVRLLARVERGELLSLRSRD +RLFAIMERTKT-KTLLPRGLGPGATIAHKTGDIGS-SVGDVGAIDLPTGKRYLAAVLVAR +PHND-SRAQELIRNFSRRAYEHf +>[subseq from] Serine hydrolase n=1 Tax=Paenibacillus sp. N3.4 TaxID=2603222 RepID=A0A5C8MES1_9BACL +--NLQQKLENAVKDERGTFGVAVKHLGTKEEA-NINEGRLFQMASSFKVPILTTLYRDVE +AGKIRLDERVKLKWEERVPGSGVLQQLDPEAVSVKDMATLMIIVSDNYATDRVLDLVGGP +KQVEAYMKEQGLNHILVKQSCWDLLTDLTSTEHNVASPRDMGKLLEMIAQKEMLSESSSN +GVLDIMLKQQF-RNRIPYLLPEQVKVAHKTGSIGS-VVNDVGIVYLPEEKGIFTIAVFSQ +GNSFRREGEQAIARLAKAAYDHf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. 35-24ZXX TaxID=1545915 RepID=UPI00053C0799 +--GLRDELAALWRGFPGKTGIAVRRIDGDWVV-GQRGGEPFPQQSVSKLWVTMAVLEKVD +RGELSLDTPVTITHDDLTLHQPLASRVAREGETVQTLINDALTASDNSANDALLRTAGGP +GVVNDFLRRKGLSSIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQASTR +LMLDTLGRTRSGPNRLKAGVPVGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLAE +TTASIPQRMQLMQAVSRAV---- +>[subseq from] Serine hydrolase n=1 Tax=Sphingorhabdus sp. YGSMI21 TaxID=2077182 RepID=A0A2D3RE71_9SPHN +--ALVREIDQLWRTFPGKTGIAIKRIDGEWEF-GHRIDEYFPQQSVSKLWVAMAMLDKID +QGRASLSDPIRIGKEDLTLHQPMAVEVEREGKSVYTLLEKALASSDNTANDALLRHAGGP +EAVRKFIDKNDLGKIRFGPGERLLQAAYLADPVDGASPRAIVRALDKLARGELLSPNSTK +LLQSILKRTRSGPNRLKAGVPAGWEFLHKTGTGQATGYNDIGIMTAPDGTRYAVVVMLGD +TTASIPERMRMMQAVTRAVGR-- +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Nostoc sp. HK-01 TaxID=196308 RepID=A0A2Z6CXD9_9NOSO +--SLKNNFQNLAATTDLTPGIFLVDLDNGGYV-DINASVGFPAASTIKVPILVAFFQDVD +AGKIRLDEMLTMQQDMVAGGSGNFQFKPAGTYSALEVATKMITISDNTATNMLIARLGGI +EALNQRFRSWGLTTTVIKNQLPDLQGT------NITSPRELGNLMAMVNQGNFVSLRSRD +IMLDIMRRTER-DNLLPSGLGSGARIYHKTGDIGT-MLADTGLVDIPNGKRYIISVMVKR +PNND-PRAEKFISSISRTAYE-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A348UZK5_9BACT +--RLTGQLAAIKDSLDGILGLAIKDLVTGKTI-FINENEIFPQASSIKIAILMEVLKQAE +ENRLRLEDFVDLKPENKVGGGPILNFLGNPSLSVHDLCVLMIVLSDNTATNLLIDLV-GM +EAVNRRLQVLGLNQTRLRRKMMDLKAA-EEGRENISTPREMLSLLEKIWQGKVLGAEQRQ +LFFDFLSLPKE--SPLQQAVPDGVTVADKPGELE-AVRCDSGLVFLRKR-PYIICVMTTY +LG-PREDGNAIIRKIGRLVYEHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A2E2ZXB8_SPHSX +----LSTITALESQFDGIVGIAVTSVDEGWSV-AANGERRMPQQSVSKLWVAMTVLDYRD +QGRLTLDDPYTVTKADLTVHQPVATLIGENGTTIRELLRRALTNSDNTCNDILLRYVGGP +DSVRDFIARKQLGAIRFGPGERLLQANYIADPPDGATATAIAQALARLKRGELLSADSTS +WLIATMESSHTGRQRLRGAVPAGWSFGHKTGTGQTAGYNDVGILTAPNGKSYTIAVLIGD +TSRTIPQRQELMQAVVASVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. ATCC 53789 TaxID=76335 RepID=A0A367PV38_9NOSO +---LKNAVQNLAANYNLAPGVFLVDLDTGNYV-DVNGSTSFPAASTIKVPILLAFFQDVD +AGKIRLDEMLTMQQDMVAGGSGDMGSKPAGTYNALEVVTKMITISDNTATNMLIARLGGM +EALNQRFRTWGLTTTTIRNILPDLQGT------NTTSPKELSNLMAIVSQGNLVSMPSRD +LMLDILRRTQR-DTLLPSGLGTGARAFHKTGDIGT-MLADTGLIVVPTGKRYIATVMVQR +PEN-DPRAEKLISSISRAAYQEf +>[subseq from] Beta-lactamase n=1 Tax=Methylibium sp. T29 TaxID=1430884 RepID=W7W894_9BURK +------------------------------------------------------------ +------------------PWSPVTEAYADGELTLAQLCHATITTSDNTAGNLILASYGGP +QALTQYARQLGDKITRLDRNEPDLNTRVEGGSLDTTSPRAMAMTMNKLLLGDALSPLSRN +LLRQWLLENTTGGKRLKAGTPADWTVGDKTGTNKT-DANDIGILLPPQGAPVLVTAYLAD +STASSQIKDATLAEVGRL----- +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sp. AX6 TaxID=2653171 RepID=A0A653YVE1_9SPHN +-----SNIERMHSDFGGRVGIAIRSIDDGWTV-SANGDQPMPQQSVSKMWVAMTILDQRD +RGRIDLSDSVTITRQDLTLHQPIASLVVRNGTTVENLLRRAITSSDNTANDRLLTLAGGP +SAVNEFIRRKSLGSIKFGPGERLLQAAYVANPPDGASAHAMVDALARLKEGNLLSAASTT +WLVSTMQNTRTGRSRVKAGTPSGWLWGHKTGTGQTAGFNDVGIMTAPDGKSYAVAVLIGE +TSRSVPQRQDLMQRVAATVAA-- +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium cloacae TaxID=120107 RepID=A0A1E1F2E1_9SPHN +--RLLAQFESLAALSDGTVGIAVQDLSTGEEQ-SLNGDTLFPMASTYKVAVAGKILAMAD +AGALSLQDQVPLDPA-----------QPARLRSLHDLIDLMLTHSDNDATDALVARAGGP +ATIHQWVAALGVKGLRVDSDTAHLLYAFTLDPRDTSTPRAMNALLAAIQLGQALKPASTV +YLLEMMERCHTGKARLKAMLPPGARIAHKTGSLN-GYGGDVGIVTLPDGRMFAVSVFVMK +DYKGRATRDSIMAHAARAAYDYf +>[subseq from] Penicillin-binding protein n=1 Tax=Tolypothrix bouteillei VB521301 TaxID=1479485 RepID=A0A0C1R0T8_9CYAN +---LKSAIQSLAASTNLTPGVFLVDLDNGSYV-DLNGAASFASASTIKIPILVAFFQDVD +AQKIRLDESLTMEKEVVAGGSGNMQKPVGTQFTALEVATKMMTISDNTATNMLIARLGGI +DALNQRFQSWGLTTTAIRNLLPDLGGT------NTTSPKELGTLMAMVGKGNLVSMRSRD +RILDIMRRTVR-NQLLPAGLGPGATIAHKTGNIGT-ILGDAGLVDVPSGKRYVVAVMVQR +PRND-PGAEKLIVSISRVAYEQ- +>[subseq from] Serine hydrolase n=1 Tax=Porphyrobacter sp. YT40 TaxID=2547601 RepID=A0A4Y6VY83_9SPHN +---FEQRIRELADPAQGRIGVAAIDLATGEEI-MVLGDQLFPMASTSKVAVAATYMSMVE +QGRFSLTSEFPLMLPVRSASSPKAPVRAGQTMQAIDLIEIMITRSSNPATDALLAAVGGP +EVVNNWVRRQGINEFSINRDIATLVRVTHIDNRDAATPRAMVRLLAGLYRGEFLSDESRR +VILGAMSRTVTGKNRIPAYIPLEARVSHKTGSLFN-TSSDIGLIECPDGRVIAVAIYVTG +QG-TKLARQDRIAAIARALYDGf +>[subseq from] HGC-2 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=C8C0M2_9ZZZZ +-qELYTNIHQFISQQKAEVGVAIIA-DGKDTV-TIENNRRYPLMSVFKLHQALAVGDYCK +RHQLSFDTLLTVDSTDLQPYSPLRDRYPHGGFSLKQLMEYTLHLSDNNACDILFKFTGGP +AVTDRYIRSLGINDFSIQYTEDDMHQDLNLGYENWSTPLATAEVIEALLKKTLFDKPHQE +FIKEALVTCQTGTSRIVHPLQKQVTVGHKTGTGDRNAINDAGFVQFPNGHRYTLVVFVKD +SQESMEDTEAIIAQISEMVYQAf +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus porteri TaxID=2126350 RepID=UPI000D107AA4 +---WQQAVENVLKEASGIFGIAAVHLETGESA-GHLDEELFQLASAFKIPIMVTLMREVE +AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI +DKVNEHMHELGLSQIHLTHNCWELLNSMPTLDNNVATPAELNRLLIMIARKEILTESSCE +QMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR +GVTDKEAAEFTIARVAKAIYE-- +>[subseq from] Serine hydrolase n=1 Tax=Blastomonas sp. AAP25 TaxID=1523416 RepID=A0A0N1LFD2_9SPHN +--GLRDELAQLWRSFPGKTGIAVRRIDGDWVV-GQRGGELFPQQSVSKLWVTMAVLEKVD +RGELSLDTEVTITPEDLTLHQPLAARVAREGESVRTLINEALTASDNSANDALLRTAGGP +GVVNDFLRRKGLSSIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQSSTR +LMLDTLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLGE +TTAGIPARMQLMQAVSRAV---- +>[subseq from] serine hydrolase n=1 Tax=Porphyrobacter colymbi TaxID=1161202 RepID=UPI000A3942C3 +--TFEQRIAQLADPSLGRIGVAAVDLATGEEV-MVLGDQLFPMASTSKVAIAATFLEMVE +KGKYSLTSEFPLMLPVASASSAKAPVRPGQYLPAIDLIELMITRSSNPATDALLAAVGGP +AVVNDWIRRQGITNFSINRDIATLVRASYIDTRDAATPRTMARLLAGIYRGEYLSDSSRQ +VLLGSMSRTVTGKRRIPAHIPLEARVSHKTGSLSN-TSSDIGLIECPDGRVIAVAIYVTG +QG-TKQAREERIAAIARALYDGf +>[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR480 TaxID=1500296 RepID=UPI000647E2CF +--DLKKNIESIIANKKADVGVSIIGPYQKETI-QINGNKLYPMLSTVKFPIALTVLKKVE +KGELSLQQKLFIKKEELLEWSPFKKEHPEGNISLEEALRWIVSYSDNNISDILMRLVGGP +ELVQQLANS---KDCIIQNNEEDMHKDWESQFVNKITPNEAIRLLEAFNNRKILNKEHTL +WLYNTMLNNTAGPKRLKGNLPSSVKVAHRTGTSFTGAINDFGIIELSGKKKIYIAVFVHD +TYEKFENAEAIIAEISKAAYDHy +>[subseq from] Putative beta-lactamase n=2 Tax=Brevibacillus brevis TaxID=1393 RepID=C0ZJM2_BREBN +---WQQVVEDVLKEAPGIFGIAAMHLETGETA-GHLDEELFQLASAFKIPIMVTMMREVE +AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELIGGI +DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPSELNRLLIMIARKEILTEASCE +LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEEKGMVAITALSR +DVTDTEAAELTIARVAKAIYE-- +>[subseq from] Serine hydrolase n=2 Tax=cellular organisms TaxID=131567 RepID=A0A175Y590_9SPHN +--RLTAAIDSLARNFDGKFGIAIRAVDDGWTVtSPGARTRMPQQSVSKLWVAMTLMDLRD +QGKARLDDPVVVRDQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP +SAVRAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALARLARGELFSETSTR +ILLDTMGASVTGRARLRAAIPAGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +SRRPIRERQQLIQAVAAAVAN-- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus fortis TaxID=2126352 RepID=A0A2P7V4S3_9BACL +---WQQAVENVLNEAPGIFGIAAVHLETGETA-GHLDEELFQLASAFKIPIMVTLMREVE +AGRIRLDQRVTLKWEERVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELVGGI +DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE +LMLDIMRRQHY-NSRLPYLLPEGTTVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR +GVTDKEAAELTIARVAKAIYE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured Dysgonomonas sp. TaxID=206096 RepID=A0A212JS98_9BACT +---LRNKIQKIIQGKDATVGVALI-VDGKDTL-TINNNFRYPTQSVYKFHLALAVLDYLN +KNNLTLDHQLYVKKGDLLPHSPLRDDYPQVELSVADIIRYTVSKSDNNGCDILFRLVGGT +AVVDRYIRGLGLSEFAIAATEEEMHGPWEVQYTNWSTPYTAAQALEIFRTHDILPQPFHD +FLWDALAGTTTGGNKIKALLPEGTFVAHKTGSSFRNAENDIAIIQLPDGRYYSLVVFVAD +SMESNDVNCGIIAQISKVVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Cylindrospermum stagnale PCC 7417 TaxID=56107 RepID=K9WQQ4_9NOST +----KTAVQNLAAANNLTPGVFLVDLDTGSYI-DVNGTTSFPAASTIKIPILIAFFQDVD +TGKIRLDEMLTMQQNMIAGGSGNLQYKPALTYSALEVATKMITISDNTATNMLIARLGGM +EALNERFRTWGLASTAIRNQLPDLPGT------NTTSPRELGNLMAMVNQGNFVSMRSRD +LMLDIMRRTER-DNLLPSGLGAGARTYHKTGDIGT-MLADVGLVDIPTGKRYIAAIMVRR +PNND-PRAEKLISSISRVTYQQ- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A6B0XRU8_9BACT +----GESLRRIARRVGDAVGVSALHVESGARI-SFNGDRPYPMASVSKVPMALEFLRRVD +LGQIDPSETVVVTVEEFRAHSPLADWSGARSVTVDSLFSLMLAQSDNTATDVILNMSGGP +EAATRHLRRLGVEGVRVDRSEARTFARYGTDPRDTATPDGMTDLLLTIHEGKGLSPESRA +WILDVLDRSRSGRGRMRGRLPPSTFVAHKTGTMG-GAINDVGIVILPDGGHLIVSVFVNT +LRRPTWRRERTIAEMTRLLYDYf +>[subseq from] Metallo-hydrolase family protein n=1 Tax=Sphingorhabdus wooponensis TaxID=940136 RepID=A0A3R8S411_9SPHN +-----NLLDDQWRAFPGRTGVAIMRIDGGEWItGKRADELFPQQSVSKTWVALTILDLVD +QGKIRLDQKIRITRDDLAVHQPIRDRVIANGVTVLSLLEQAIIGSDNTANDSLLRTAGGP +QAVQNFLLRKKLGAIRFGPGERAMQSRYLADPIDGASPEAIVRALAKLAKGELLSPASTR +LILGIMSRTSSGPNRLKAGVPAGWQFVHKTGTGQATGYNDIGLMTAPDGTRYAVAVMMGS +TTASIPQRMAFMQFVSRTVATY- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X708_9BACT +-kALEQKLTSICSRAQGSIGVTAVHVETGRAV-SVNGNAVLPLYSVFKLPLAITVLKDVE +ANRLKVEQMVHVTPDEIVPGTPENTALWAKPRTVAELIEFSISRSDNTSTDKLLQLVGGP +TRVTEQMRSLGFNNLDIHSTVMGYVKT--RQSVNTGSADDLANLLTQLQQGKILQPAQSQ +LLVGYMRGTITGMRRLRGDLPPGTVVADKTGSGERNTTNDVGLITLPNGGTIAMAVLVTD +SRLVDTAQEKIIAELARAAFDAy +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Leaf38 TaxID=1736217 RepID=A0A0Q4L612_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMALMIIRSDNQATDQLLAALGGP +VAVQQWLSSHNIPGIRMDRTIAQLLRGHLADSRDVSTPVAMVTLLNKLDNGTVLTAQSRA +LLLDLMGRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG +GR----DRQPVIAEVARVIYDRf +>[subseq from] class A beta-lactamase n=1 Tax=Larkinella soli TaxID=1770527 RepID=UPI000FFBAC40 +-qNLKRDICQIISQNRAHVGISIKGFEKEDTI-NINANDTFPLMSVFKFHIALAVLQRVD +DGVLKLTQKVLVEKSQLHSWSPMRDQYPHGQLSLDEILRYTVSNSDNNGCDILLNLIGGA +KGLQKYIRSLGADDFTVSVNEFQMRS-WENSYLNYSTPMETTKLLEKFYNGLILKANSTD +YLYRLMVETTRGTRYMKSGLPQAAEIAHRPGLSGRIAMNDVGIVKLPNGQYFIISIFLKD +IMQDDRQAEEFFSEVARLTWEYf +>[subseq from] Beta-lactamase class A n=1 Tax=Parasphingopyxis lamellibrachiae TaxID=680125 RepID=A0A3D9FFP4_9SPHN +--QLSDSVTALGSAFNGEVGIAVRDVEEGWTV-SWNGERFLPQQSVSKTWVAMTVLDQVD +RGEMSLDRMVRVRPEDAVVHQPMLSRMGNGGASIRELFTQAMTRSDNLANDRLLWLSGGP +EAVRAFFARNNLEGLRFGPGERELQSRYLADPVDGATANGMVEALARLVRGELLSERSTE +LMISTMRASRTGPQRLRGGVPSGWQFGHKTGTGQVAGYNDVGIVTTPDGRNYAVAVLIGN +TRVGIPARQRLMQAVMGQVVSH- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas sp. S6-262 TaxID=1166340 RepID=A0A1H8HBQ2_9SPHN +---LQMAIQSLARGFQGRAGIAVRAVDEGWTV-EANGRQREPQQSVSKLWVAMTLLDLRD +QGKARLDEPIVVRPEDITLHQPIAYLALKGDTTVGDLLTRALTHSDNTANDRLLTYVGGP +RAVRAMIERKQLGDIRFGPGERLLQAAYTSDPPDGAAPLSIADALARLARGELLSETSTR +ILLDTMGASVTGRARMRAALPAGWTIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +STRPIRERQVLIQNVAAAVTT-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingorhabdus contaminans TaxID=1343899 RepID=A0A553WBJ4_9SPHN +-----NLLHEQWRLFPGKTGVAVMRIDGGDWViGRRLDELFPQQSVSKAWVAMTVLDQVD +QGKLKLDQKVRITIDDLAVHQPIRERVIANGESVLSLLEQAITASDNTANDSLLRTAGGP +QAVRAFIAKKRLGAIRFGPGERALQSRYLADPVDGASPEAIVRALAKLAKGELLSAASTR +LLLDIMSRTSSGPNRLKAGVPAGWRFLHKTGTGQSTGYNDIGIMTAPDGTRYAVVVMMGS +TTSSIPERMAFMQFVSRSVATY- +>[subseq from] Beta-lactamase class A n=2 Tax=Apibacter mensalis TaxID=1586267 RepID=A0A0X3APV5_9FLAO +-qKLEKEIRSIIENKKATVGVAVIY-DSKDTL-TVNNDIEYPAASVFKFHQALALLDYMN +KNLLSLESKLYLKKSDMKNYSPLANEHPEGNISIGDLLSYTVSKSDNNASDALYYYMNGT +QMTDMYLRTLGSKKFSIEATEQELSQEFNNQYLNWTTPLEAAQLLNIFITKDIFCKNYKD +FLIQAMAKSETGSDKLKAFLPKKVLIGHKSGSSSRNADNDIGFVYLPNGKQYSIAVFIKD +SKEDDPTNARMIADISTIVYKFy +>[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=root TaxID=1 RepID=A0A3E4N3M0_9BACE +-qELYTNIHQFISQQKAEVGVAIIA-DGKDTV-TIENNRRYPLMSVFKLHQALAVGDYCK +RHQLSFDTLLTVDSTDLQPYSPLRDRYPHGGFSLKQLMEYTLHLSDNNACDILFKFTGGP +AVTDRYIRSLGINDFSIQYTEDDMHQDLNLGYENWSTPLATAEVIEALLTRTLFDKPHQE +FIKEALVTCQTGTSRIVHPLQKQVTVGHKTGTGDRNAINDAGFVQFPNGHRYTLVVFVKD +SQESMEDTEAIIAQISEMVYQAf +>[subseq from] Serine hydrolase n=1 Tax=Euhalothece sp. KZN 001 TaxID=1884791 RepID=A0A2K3BIN5_9CHRO +--TLKQTLQRLGSQSQLNPGAFIVDLDSGEYV-SLQGEKAFSAASMIKVPILIAFFHAWD +KGKLKLDERLTMTEEVKAGGSGNMQEAVGTEYLALETAAKMIIISDNTATNMIIKRLGGK +EALNQLFAEWGLEHTRLRNPLPDLEGT------NTTSAKELVELLAKLNQGKLVSARSRD +QIFRIMRETKT-RTLLPQGLGEGASIAHKTGDIGS-LVGDVGIIDRPSGKRYLAAIMVER +PHND-RAANELIRQFSRETYQYf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9SGJ7_9BACT +-qKLESTINDIDRSLDGVIGVAILDLASGQKF-LLHADEVFPQASSIKIAVLAELYHQAQ +TGKLKLNDLYTVQASDLVPDSDIMGGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GM +ENVDGLMTSLGLTRTRLRRKMMDLKAA-SEGRENISTPGEMMILLENLYRGKVLNKEMTE +DFFKVLSTHKS--SFIPRELPEGLKIANKPGELER-VRNDSGVVFAEKR-PYVICVMTTY +LQR-ERDGEEAISRISLAAYRTf +>[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=Alistipes TaxID=239759 RepID=A0A3D1NSQ3_9BACT +--DLSYRLKKVIKDKKAEIGIAVI-LDAQDTV-TVNNDDRYPLMSVFKFHQALAVADYLD +RNGLTPDTEIFIPEEELVPYSPLREEFPEGELSVSRLLEYSLQLSDNNACDILFEHTGGP +AATDRYVRSLGLHDFAIAATEQQMHDDPQTCYENWSTPLEAAALLELLVTEQILTPTLRE +MIRQNLISCKTGADRLPKPLSTGAVIGHKTGTSDRDGTNDLGFVILPDGTRYTIAVFIKD +SAENPETNARIIADISETVYRY- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Alistipes sp. TaxID=1872444 RepID=A0A3B9CLP9_9BACT +-tELEQALRTLVERKRAETGIAVI-LNGTDTV-TVNDAGRYPMMSVFKFHQALAVADFLD +RNGLPLSTPLPIRESDLLPYSPLRDAYPQGGMSIGELLVYTLQLSDNNACDLLFRYIGGP +TVADRYIRTLGIEGFAVEATEEEMHRDLTACYRNWSHPLDAARLLEMLITRPLFRDASQE +FIIRTMTGCNTGPERLPKPLATGAVIGHKTGSGDRNGTNDIGFVQLPDGRHYTIAVFVKD +SQESLQETERIIAEASDIVYRY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. Ant17 TaxID=1461752 RepID=A0A013XUW5_9SPHN +--RLIAQFQRFATLTDGTVGITVRDLASGESL-SLNGDTLFPMASAYKVAVAGKIFAMID +AGQLALTDIVSRDVATMG---------PGAPLPVAQLLDLMLTRSDNNATDMLVARAGGP +SAVNAWVAGLGIKGLRVDSNTADLLYAFARDPRDSATPTAMTDLIAAIRTGKALSPASTH +AFITIMERCRTGKARLSGMLPPGTTIAHKTGTIN-GTGNDTGVVTLPDGRMFAITVFVMQ +DHRGRVMRDRIMAEAARAAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf230 TaxID=1735694 RepID=A0A0Q4J826_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIVHSDNEATDQLLAALGGP +VAIQQWLSSHRITGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLAAQSRQ +FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG +GR----DRQPVIAEVSRAIYDYf +>[subseq from] serine hydrolase n=2 Tax=Sphingomonas sp. Leaf257 TaxID=1736309 RepID=UPI0009E894EB +-----STINRLSASFAGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD +RGRARLDEPIVVRREDLTVHQPIAMLVKGDGTTVGELLNRALTMSDNTANDRLLTYVGGP +QAVRAMIAAKRLGDIRFGPGERLLQAAYVSDPPDGAAPIAIADALARLARGELLSETSTR +ILIDTMEASRTGHARLRAAVPSGWQIAHKTGTGQNAGFNDVGLLTAPDGRRFTIAVMIGD +TTEDIRKRQQLIQNVAAAVAN-- +>[subseq from] serine hydrolase n=1 Tax=Caenibacillus caldisaponilyticus TaxID=1674942 RepID=UPI000988386C +--TLQEKLEKVLADKPGTFGVAVRHLGTGESA-AINGDVLFQTASSCKVAILAALFHEAE +KGRLSLETRIRLSKSDLVPGSGVFQYDIGAEISVKDLATLMIIVSDNLATDKILEMV-GK +DNVNALTRALGLKNSRIEHTIWELLCFDMDRPNNVSTPEEMNRLLVLLAEGRLVSKAASA +AMIDILKKQQF-GHRLPYLLPDGATVAHKTGTIGS-VVNDVGIVYFPDQEGFAISVFSRG +CE-TAREAEQTIAELAKTAYDHf +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_1_40CM_65_14 TaxID=1803459 RepID=A0A1Q7H548_9BACT +--RLRTHITQAMTEARGRMGVAIKHLESGTEV-VVNADEKFPMASTFKLPVLVTLYDRAK +KGQVKWDETVDVGVHDQHLGSGDLYDVPGVKLSLHNVANLMMMVSDNSGADICLTRA-GA +DNVNALMSSLGAGDIHVDRPTQELILKFAADARDQATPKAFVTLLEKMWRGEAVDKASSE +AMLETMKRCRTGAGRIKGLLPSNTTVAHKTGTIG-GVVDDVGIIYLPEEGHVAIAVLSKQ +TRATDVEVERAIAQIARYAYDYf +>[subseq from] ClassA n=14 Tax=root TaxID=1 RepID=A0A127SQY3_9BACT +-qNMTQEIEKIIKGKQASVGVAIIH--NDDII-AIANEDKYPTMSVFKFHIAVTALKKME +AENIPLDKMVYIKQKEMLKYSPLRDKYPDQGISYRDIIKYTVSISDNNTCDWLIRFVGGI +DKVDSYIKSLGIKDMNFTETEESMHTDIMLCYNNWSTPLAIAQLLKKLHTENILTKEHFA +FLETAMLDCVSGKNKLIAGLPTDIKFGHKTGRSNRTSEGDAGVIYLPNGEKCYIVVLIKD +SRESDDDNAKIMADISNIVYRH- +>[subseq from] Putative beta-lactamase class A n=2 Tax=Sphingomonas parapaucimobilis TaxID=28213 RepID=A0A0A1W6Y4_9SPHN +-----STINRLSAGFAGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD +RGRARLDEPIVVRREDLTLHQPIAMLVKGDGTTVGELLNRALTMSDNTANDRLLTYVGGP +QAVRAMIAAKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR +ILIDTMEASRTGHARLRAAVPSGWTIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD +TTEDIRKRQLLIQNVAAAVAD-- +>[subseq from] Serine hydrolase n=2 Tax=Nostocales TaxID=1161 RepID=A0A1B7W1B1_APHFL +----KNSLQTLTTASDLTPGVFLLDLDNGGYV-DINGNASFPAASTIKIPILMAFFQDVD +AGKIRLDEILTLEKEMIVGGSGVQYQTPGSKYTALDLATKMITISDNTATNMLVAKLGGQ +EALNGRFRGWGLTTTMIRNPLPDLGGT------NTTSPRELGNLISMVNQGTVVSMRSRD +LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADVGLIDVPTGKRYIAAIMVQR +PNND-PRAAKLISSISSAAYEHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sphingomonas sp. Sph1(2015) TaxID=1628084 RepID=A0A1R1Z0Q1_9SPHN +-----STINRLSAGFAGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD +RGRARLDEPIVVRREDLTLHQPIAMLVKGDGTTVGELLNRALTMSDNTANDRLLTYVGGP +QAVRAMIAAKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR +ILIDTMEASRTGHARLRAAVPSGWTIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD +TTEDIRKRQLLIQNVAAAVAD-- +>[subseq from] CME family class A beta-lactamase n=1 Tax=Elizabethkingia occulta TaxID=1867263 RepID=A0A1T3MZX1_9FLAO +htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHITLAVLNQVD +KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT +NTVQKLMDVNGVKNFQVKYNEEEMSKKVQAPYANYNTTASMVKTLKAFYKGVFLSKRSTA +FLMEIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLGSGKHYAIAVFVKD +SMESEEVNCGMIAQISKVVWDA- +>[subseq from] Beta-lactamase n=1 Tax=Anabaena cylindrica (strain ATCC 27899 / PCC 7122) TaxID=272123 RepID=K9ZMK7_ANACC +----KTDVQNLAAANNLTPGVFMVDLDTGAYV-DINSTASFSAASTIKVPILIAFFQDVD +AGKIRLDEMLTVQQEMIAGGSGTLQTTVGSQYTAIDVATKMITISDNTATNMLIARLGGQ +EVLNERFRSWGLATTIIRSPLPDLQGT------NTTSPRELGNLIAALNQGNMVSMRSRD +IMLDIMRRTQR-NNLLPSGLGEGAKSYHKTGDIGT-MLGDAGLIDIPTGKRYIAAVMVQR +PNND-PTAEKLISAISSAAYQHf +>[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia ursingii TaxID=1756150 RepID=A0A1T3F3G6_9FLAO +-pQLKKTLESIISGKKATVGVSVMSPDEKEMT-GINANQMLPMLSTVKFPLALAVLYEVE +KGKLSMNQKLFIKKEELLDWSPFKEKYPAGNITLEEALKWTVSYSDNNLTDILIRLIGGP +ETVQEFMDS---SSFIIKNDEEGMHKDWDSQFVNKITPNFAVLLLQEFSNGKILNKTNTQ +WLYNAMLNNVSGKKRLKGNLPTGVKVAHRTGTSFTGAINDYGIIELLGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] Beta-lactamase n=1 Tax=Sphingosinicella sp. BN140058 TaxID=1892855 RepID=A0A4P6FPU1_9SPHN +------------------------------------------------------------ +------------------------------GVSAATLMEQMITRSDNRATDLLMNRLGGP +AAIDSWLRVRGIGGMRVDRTIAQLLSDRRKDIRDSSTPAAMLNLLRMLDTQPVLKPESRL +RLLDLMARCKTGSNRMRALLPAAVKVEHKTGTLT-GYTGDVGFLTLPSGRRLAVAFFARG +GS----NRPAVIATAARAIFDAf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. NIC1 TaxID=1961362 RepID=UPI0007C0D80B +--RLTAAIDSLARNFDGKFGIAIRAVDDGWTVtSPGARTRMPQQSVSKLWVAMTLMDLRD +QGKARLDDPVVVRDQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP +SAVRAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALARLARGELFSETSTR +ILLDTMGASVTGRARLRAAIPAGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +SRRPIRERQQLIQAVAAAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Bacteroidales bacterium TaxID=2030927 RepID=UPI0011CAD63E +-qNLTQEIEKVIQEKQASIGVAVMY--GDKTF-AVANHKKYPIMSVFKFHIAVTALKKME +TENIPLDSMIYIEPKQIHKFSPLRDKYPNQRLSYRDMIEYTVAHSDNNTCDLLIEFVGGI +KNVDTYIKSLGIKDLNLTETEHDMHENIMNCYNNWSTPLSIAQLLKKVYTENILTEDHFT +FLEKIMLNCSSGKDKLKAGLPADIKIAHKTGHSDRTSEADAGVIYLPNGEKCYIVVLIKD +SRESDKDNAKIMADIANLTFRI- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides cellulosilyticus TaxID=246787 RepID=A0A0P0GLD1_9BACE +-qKIEQQIDSFLKDKKATVGVAVLA--NDEIVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KDHIGLDSLIEVKSSQLKPYSPLRDEFPDQDISLGELLKYSISQSDNNACDILIEYAGGI +DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD +FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQETDTDNAAIIASISKIVYDT- +>[subseq from] Uncharacterized protein n=1 Tax=Rheinheimera sp. TaxID=1869214 RepID=A0A349LW26_9GAMM +---------------YARVGIYLLDLQQAQAW-SLNNNPSYPLLSSFKLPLAIWVLKLVE +TGQLSLEQAVPIQRSALMQWSPLLDEHKAANLTVRELLRYSVELSDNNAADVLLQLSGGT +AALQQYLQQQGLQNTVIQATEQQMHQGFAAQYRNHSRPSDMALLLAQLANTELLHAEQSD +LLVQWLRDTPTGAKRVKAGLPDGSIWLHKTGTSGRAAVNDIGLLQLPDGRQFVLVMLVQD +SHWSLDDTEALMARLTARLV--- +>[subseq from] D-alanyl-D-alanine carboxypeptidase n=1 Tax=Planctomycetes bacterium Pan181 TaxID=2527972 RepID=A0A518AS84_9BACT +---LEKLVLPLIENHRGEVGVMIRFLPTGETF-AYRADQAMPTASLIKFPIMMATYKAIH +EGKLKLEQPITLKEDDQVPGSGVLTTHFSPGLSLRDAIQLMIAFSDNTATNLVIDQV-GI +EETNRLMESLGCDETRLNSKVYRRDTRSQKYGLGSTSCRDMIQLAELVSNDEFLGKEDCE +QILKHLYDCTA-KSGVPRLLPESIRIAHKTGSVGD-SRTDAGLIDTPKGK-IAFCVLTTK +NDDDSNEAELLAAEIGLIAYNYf +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A6B1AJP0_9BACT +----GESLRRIARRVGDAVGVSALHVESGARI-SFNGDRPYPMASVSKVPMALEFLRRVD +LGEIDPAETVVVTVEEFRPHSPLAAWSGARSLTVDSLFSLMLGQSDNTATDVILNMSGGP +EAATRHLRRLGVEGVRVDRSEARTFARYGADPRDTATPEGMTDLLLTIHEGKELTPESRA +WILDVLNRSRSGRGRMRGRLPQSTFVAHKTGTMG-GAINDVGIVTLPDGGHLIVSVFVNT +LRRPTWRRERTIAEMTRLLYDYf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf38 TaxID=1736217 RepID=UPI0009E8C6AA +------------------------------------------------------------ +---------------------------------AAKVMALMIIRSDNQATDQLLAALGGP +VAVQQWLSSHNIPGIRMDRTIAQLLRGHLADSRDVSTPVAMVTLLNKLDNGTVLTAQSRA +LLLDLMGRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG +GR----DRQPVIAEVARVIYDRf +>[subseq from] serine hydrolase n=1 Tax=Novosphingopyxis baekryungensis TaxID=279369 RepID=UPI0012EB2C46 +----VSEVNALWRGFPGTTGIAVRRIDGDWSF-GERKDELFPQQSVSKTWVTLTILDQID +QGKLRLSDPVTITVADLAVHQPIRDRVIANGETVGSLIEQAITKSDNTANDALLWKAGGP +DAVRDFISRKNLGAIRFGPGERLLQSAYLRDPMDGASPQAIVDALAKLARGELLSPASTQ +LMLSTMSRTSSGPNRLKAGVPGGWNFLHKTGTGQSTGYNDIGIMTAPDGTRYAVAVMLGD +TTASIPERMRLMQAVSRAVARY- +>[subseq from] Beta-lactamase n=1 Tax=Anabaenopsis circularis NIES-21 TaxID=1085406 RepID=A0A1Z4GAT6_9CYAN +--SLKNNVQNLAATTDLTPGIFLVDLDNGGYV-DINASVGFPAASTIKVPILVAFFQDVD +AGKIRLDEMLTMQQDVVAGGSGNFQKPVGTQYSALEVATKMITISDNTATNMLIARLGGI +EALNQRFRSWGLTTTSIKNQLPDLQGT------NITSPRELGNLMAMVNQGNFVSLRSRD +IMLDIMRRTER-DNLLPSGLGSGARIYHKTGDIGT-MLADTGLVDIPNGKRYIISVMVKR +PNND-PRAEKFISSISRTAYE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522QUU7_9BACT +--SLRQQIASICESKHAIIGVYVQVIESGDTL-SFNGIKHFPMQSVFKFPLALYILSQVD +KGKLSLNQRLFISKKELLPWSPLRDSHRGGNMTLRDLLQYTISHSDNNGCDILFRLAGGP +DKVNHYIHGLGMKNISIKTTETQMHSAWNVQFSNWATPVAVTKLLVLFYNGKILSPASRD +FLLKMMEGTTTGANKIKGLLPSGTLVAHKSGLSDR------------------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-CE-1A-559 TaxID=2135657 RepID=A0A4R2SS28_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIVHSDNQATDQLLAALGGP +VAIQQWLSSHRITGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLAAQSRQ +FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG +GR----DRQPVIAEVSRAIYDYf +>[subseq from] Serine hydrolase n=1 Tax=Alphaproteobacteria bacterium HGW-Alphaproteobacteria-17 TaxID=2013663 RepID=A0A2N3CTD9_9PROT +---LAERIHFLWRGFPGKTGIAVQRIDGEWAV-SQRGGELFPQQSVSKLWVAMAALDAVD +QGRLRLDQQVRIGPEDLTLYQPLAARVRSEGMSVRALIETAITQSDNTANDSLLRTIGGP +TTVQSFLARKNLGAIRFGPGERQLQSRYLADPVDGASPDAIASALTRLARGALLSPESTE +YLLGVMSRTRSGPNRLKAGLPSDWKFLHKTGTGQTAGYNNIGIATAPDGTRYAIVVLMGT +TTSPIPSRMALMQAVSGAVAE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=Q2LA82_ACIBA +---LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPCEKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLV------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter aurantiacus TaxID=1463599 RepID=UPI00132C2E94 +--AFEKRIAELADGSRGRIGISAVDLSTGYHL-DILGDQRFPMASTSKIAIAATFLEGVE +KGRWSLTSEFPLLVPQRSASSTVAPVSTGKHLPAIQLIELMITRSSNPATDALLRVVGGP +VAVNNWAARNGIREFSLDRDIATLVRATYIDRRDSATPTAMTDLLTALYRGTTLSDSSRS +VILGAMSRTVTGKRRIKALIPSEASVSNKTGSLNN-TSSDIGYIETPDGRTIALAIYVTG +QG-SRAQREAKIAQLARALYDGf +>[subseq from] Serine hydrolase n=1 Tax=Proteobacteria bacterium ST_bin13 TaxID=1978761 RepID=A0A1W9JKQ8_9PROT +---LSASINAVRAQFDGTVGIAVRSVDKGWSV-ATNGDLKLPQQSVSKLWVAMTVLDARD +SGRLTLDDPVTVTREDLTLHQPIAAMVTGDGATVGELLQRALTTSDNTANDRLLRYVGGP +EAVRAFIKRKGLGAINFGPGERLLQSSYVSNPPDGAAPSAIAGALAMLKKGELLSSPSTS +YLISTMESSKTGRQRLRGAVPEGWRFGHKTGTGQTAGYNDVGILTAPDGQSYTLAVMIGD +TPRPVTERQALMQSVVASVVAY- +>[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00124A601F +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTA------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0011C995C0 +----------------------ALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNEVAFIYPKNQ----------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium RIFCSPLOWO2_12_FULL_63_15 TaxID=1802170 RepID=A0A1G3JWU9_9SPHN +--RLIAQFQRFATLTDGTVGITVRDLASGETL-SLNGNTLFPMASAYKVAVAGKIFAMID +AGQLALTDIVPRDV---------ATMGPGAPMPVARLLDLMLTQSDNHATDMLVARAGGP +TAVNGWVAGLGIKGLRVDSNTADLLYAFARDPRDSATPTAMTDLVAAIRTGNALSPASTH +AFITIMERCRTGKTRLPGMLPPGTTIAHKTGTIN-GTGNDTGVITLPDGRMFAITVFVMQ +DHRGRVMRDRIMAEAARAAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf208 TaxID=1735679 RepID=A0A0Q4F639_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIVHSDNQATDQLLAALGGP +VAIQQWLSSHRITGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLAAQSRQ +FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG +GR----DRQPVIAEVSRAIYDYf +>[subseq from] Beta-lactamase n=4 Tax=Bacteroides TaxID=816 RepID=A0A174U954_BACVU +-kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ +KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV +NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLEVFMTQDFMRNEYTD +FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD +SKENMETNAKIISDISAAVYRY- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2E4HU16_9BACT +--RLRGALLAIAQRFPGDVGVYVHHIESGMET-GVDEDTPYGMASTYKVPILVELMTRVE +AGDLRLDDRVAVEAEDQHIGSGLLSTLWAPGMSLRNIATFMIILSDNSATDMLIDRL-GA +DQITARMRSLGFQNIRVDRTTLELILAFYGGDKDKASARDMTELLVMISEGTAVSRGSSE +VIMEILSRTQTGANRLRGLLPPGYSIAHKTGTIGR-IVNDVGVITMPGDGRFAISVFTLG +NEADTELGEDTIAEMARTAYDFf +>[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium sp. JV274 TaxID=1932669 RepID=UPI000985B683 +--DLKKTIESIISNKKADVGVSIIGPDQKETI-QINGNTLYPMLSTVKFPIALTVLKKVE +KGELSLQQKLFIKKEELLEWSPFKKEHPEGNISLEEALKWIVSYSDNNISDILMRLVGGS +EPVQQLVNS---KDCIIQNNEEDMHKDWESQFVNKITPNEAIRLLTAFSNGKILNKEHSL +WLYNIMLNNTAGPKRLKGSLPPQVKVAHRTGTSFTGAINDFGIIELSDNKKIYIAVFVHD +TYEKFENAEAIIADISKATYDYy +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Sulfopaludibacter sp. SbA4 TaxID=2043165 RepID=A0A2U3LW36_9BACT +---LTRQWQRIASGTDGVVGAAALHLNSGRHA-SLHGGERFPLASVCKLPIAIAILAMAG +EGKLSLDDQIEIPLQDVVPVSIVAERWPGQKFRLNELLEWMVAKSDNSAVETLFRMSGGA +AGMAARFLQWQVEGMRVDRSERECALRFMADPRDTATPDGTVHLLQRAFRGELLSASLTG +RLVEILEAATTGSARIKGLLPAGTVVAHKTGTTANGGTNDVGVITLPKGGQLAIAVYVKG +STRDLATREKIIAGIARSAF--- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9TGZ4_9BACT +-qKLESTINDIDRSLDGVIGVAILDLTSGQKF-LLHADEVFPQASSIKIAVLAELYHQAQ +TGKLKLNDLYTVQASDLVPDSDIMGGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GM +ENVDGLMTSLGLTRTRLRRKMMDLKAA-SEGRENISTPGEMMILLENLYRGKVLNKEMTE +DFFKVLSTHKS--SFIPRELPEGLKIANKPGELER-VRNDSGVVFAEKR-PYVICVMTTY +LQR-ERDGEEAISRISLAAYRTf +>[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter sp. TH134 TaxID=2067450 RepID=A0A2N4WYK2_9SPHN +--SFEQRIADLANPAMGRIGVAAIDLATGEEV-MVLGDQLFPMASTSKIAVAGTFLEMVE +QGRFSLTSEFPLMLPVASAYSSAKAPRPGQYLPAIDLIEIMITRSSNPATDALLAAVGGP +AVVNDWIRRQGIAEFSINRDIATLVRAVHIDTRDAATPRAMVRLLAGLYRGDFLSDQSRQ +VLLSAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGLIECPDGRVIAVAIYVTG +QG-TKLAREERIAAIARALYDGf +>[subseq from] Serine hydrolase n=2 Tax=Sphingomonas sp. Leaf25 TaxID=1735692 RepID=A0A0Q4IFW8_9SPHN +--ALVQAINALGGGFQGHVGIAVRSIDDGWVV-GHAMDRRMPQQSVSKLWVAMTTMSAID +EGRLALTTPVAITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTMSDNTANDKLLNLVGGP +VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLHHGMLLSQQSTA +WLLDTMAHTRTGRARIRAALPPGWSVAHKTGTGQTAGFNDIGIITAPDGKAYAIAVMIGD +TARPVPERQQLIQTVVSSIV--- +>[subseq from] serine hydrolase n=1 Tax=Planktothrix paucivesiculata TaxID=1678308 RepID=UPI0012DDC1A3 +---LKTAILGLAKDSKLKPGVFLVDLDTGKYV-DIQGQEAVPAASTIKVPILVSFFQAVD +EGRIRLDEVLTMEEKHIAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI +ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSAKDLVNLMADINQGKLVSLKSRD +FMLRIMQQTRN-RSLLPRGLGDGAFIAHKTGNIDS-VSGDIGLIDMPNGKRYLVGVLVQR +EA-DDPQANELIRQISSTIYQYf +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera malacea cyanobiont' DB3992 TaxID=1206980 RepID=A0A2D0HEL8_9NOSO +-kALEPQIKALMSRYSLKTGMFFLDLDTGDYL-DIGGDRVFPAASTIKLPILIAFFQDLD +AGKVTLQENLTMRRDLVTNGSGSMQERVGKKYTALETITKMITISDNTATNMIIDRLGGA +AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR +PYKD-TRGRDFIRQVSRLVYDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Dysgonomonas alginatilytica TaxID=1605892 RepID=A0A2V3PRU2_9BACT +--ELRKNIGSIIENKNATVGVAII-FNGKDTL-TVNNQYRYPTMSVYKFHQALAVLDNLN +RRNLPLDQQIYISKSALQPHSPLRDARPEGNMPIKELLQYSVSQSDNNACDILFSFLGGT +DYVEKYIKSLGIMQIAITATEKEMHDDHSKQYANWTTPYSAVELLEKFRQDDWFPPKYKN +FLWESLIDTSTGQDKIKALLPPNTVVGHKTGTSFRNADNDLGFIELPNGKQFSIAVFIVN +SIEDDKTNATIIAQISKAAYDYy +>[subseq from] class A beta-lactamase n=1 Tax=Alistipes onderdonkii TaxID=328813 RepID=UPI000A05ED1A +--QFESRLDEIVSGHKAFVGVAIR-TPDGKTV--ARNDSLLPMMSVFKFPVALAVLDRMQ +REGTPLTQPISITPDLLLPYSPMRDSLPESGLTLGQLLRYTVSESDNIACDILLREAGGP +EAVEAYVRSLGIGGICIAASEEEMHRGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA +LLQRLLCEATTGTNKLKAGLPAGTVIGHKTGSSDRTADNDAGYVLLPDGCRYCIAVFVTE +SEENDAANAAIAAAVSRAAYEYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas bacterium TaxID=1895847 RepID=A0A3D0W9Y7_9SPHN +-----TDIDGLVGAFGGKVGVAVKSIDTGWMV-SKNGDVPMPQQSVSKLWVTLTAMDQID +QGRITLDDPLTITRNDLTLHQPIASLLQNGVTTVRELIRRAMTMSDNTANDRLLRHVGGP +PAVNAFIARHSLGAIRFGPGERLLQSAYVANPIDGAAAASIANALTKLRRGELLSPQSTS +YLINVMESSRTGHARLRASVPPGWRLAHKTGTGQTAGFNDVGILTAPDGRAYAIAVMIGD +TRRPTQERQKLMQNVVARVVAY- +>[subseq from] CepA (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SIF1_9BACT +--DLSYRLKKVIKDKKAEIGIAVI-LDAQDTV-TVNNDDRYPLMSVFKFHQALAVADYLD +RNGLTPDTEIFIPEEELVPYSPLRKEFLGGELSVSRLLEYSLQLSDNNACDILFKHTGGP +AATDRYVRSLGLHNFAIAATEQQMHDDPQTCYENWSTPLEAAALLELLVTEQILTPTLRE +MIRQNLINCKTGADRLPKPLSTGAVIGHKTGTSDRDGTNDLGFVILPDGTRYTIAIFIKN +SAENPETNARIIADISETVY--- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc calcicola FACHB-389 TaxID=1357508 RepID=A0A1U7IS84_9NOSO +---LEPQVKALMSRYSLKTGMFFLDLDTGDYL-DIGGDRVFPAASTIKLPILMAFFQDLD +AGKVTLEEKLTMRRDLVTNGSGTMQESVGKKYTALETITKMITISDNTATNMIIDRLGGA +AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNNKLVSPPSRE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR +PYKD-SRGRDFIRQVSRLVYDY- +>[subseq from] serine hydrolase n=1 Tax=Nostoc piscinale TaxID=224012 RepID=UPI0009F83437 +---LKNAVQNLAATTDLTPGIFLVDLDNGGYV-DINAAVGFPAASTIKVPILVAFFQDVD +AGKIRLDEMLTMQQDMVAGGSGNFQKPIGTQYSALEVATKMITISDNTATNMLIARLGGI +DALNQRFRSWGLTTTVIKNKLPDLQGT------NITSPKELGNLMAMVNQGNFVSLRSRD +IMLDIMRRTER-DHLLPSGLGAGARIYHKTGDIGT-MLADTGLVDIPNGKRYIISVMVKR +PNND-PRAEKLISSISRITYE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sporomusa malonica TaxID=112901 RepID=A0A1W2CWH1_9FIRM +---LHQKIQAILAQYTGRSGIVIINQNTGARL-ELHPDMVFPAASMIKVPIMIEVMRQAA +AGLIDLDETLEITSQVQTGGAGILKELRSGVMTVRELVTLMIILSDNTATNILIDLV-GM +NSINATITSLGLRSTVLRRKMMDFEAA-KAGKENYTSAADLAHLFASIASSSALPPTHSA +LMLDILKRQQV-RDKLPFYLPEEIIIAHKTGTLP-GAEHDAGILFVPGG-SYIICVLTAD +LAAN-YEGLQLVANIGKTIYDY- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas japonica TaxID=511662 RepID=UPI0011211A98 +--ALVTTINGLADAFGGRVGIAVKSIDDDWMV-AKNGELALPQQSVSKLWVAMTTLDALD +KGRISLDQSVTITRSDLTLHQPIAALVKDGGTTVRDLLQRAMTRSDNTANDRLLKLVGGP +ASVNAFIADRNLGNIKFGPGERLLQAGYVANPPDGAGAAAIANALARLQRGDLLSPASTR +WLISTMESSKTGRARLKAGTPAGWSLGHKTGTGQTAGFNDIGILTAPNGKSYAIAVLIGD +TSRPVPQRQELIQNVAAAVAA-- +>[subseq from] serine hydrolase n=1 Tax=Sphingopyxis sp. L1A2A TaxID=2502247 RepID=UPI0010F812A1 +---LTERIHFLWRAFPGKTGIAVQRIDGEWAI-AERGGDLFPQQSVSKLWVSLTALDAVD +QGRVRLDQPVRIGPEDLTLYQPLAARVRAQGMTVRQLIETAITQSDNTANDSLLRTIGGP +GAVRAFMAKKDLGAIRFGPGERLLQSNYLANPIDGASPTAIASALARLARGTLLSPESTD +YLLGVMSRTKSGPKRLKAGLPPGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGT +TTSPIPARMALMQAVSSAVAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingopyxis sp. YR583 TaxID=1881047 RepID=A0A1H6G6X8_9SPHN +---LNDRIFELWRAFPGKTGIAVQRIDGEWSL-SQRGAELFPQQSVSKLWVTLSVLDAVD +QGRMTLDQRVRIGPEDLVVHQPLAARVRSEGMSVRDLIETAITHSDNLANDSLLRTVGGP +NAVRAFITKKDLGSIRFGPGERLLQANYLANPVDGASPSAIASALTRLARGTLLSPKSTE +YLQGVLGRTKSGPRRLKAGLPPGWQFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGS +TTASIPARMALMQSVSSAVAEY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. 28-62-20 TaxID=1970433 RepID=A0A258SCG0_9SPHN +---LSASINAVRAQFDGTVGIAVRSVDKGWSV-ATNGDLKLPQQSVSKLWVAMTVLDARD +SGRLTLDDPVTVTREDLTLHQPIAAMVTGDGATVGELLQRALTTSDNTANDRLLRYVGGP +DAVRAFIKRKGLGAINFGPGERLLQSSYVSNPPDGAAPSAIAGALAMLKKGELLSSPSTS +YLISTMESSKTGRQRLRGAVPEGWRFGHKTGTGQTAGYNDVGILTAPDGQSYTLAVMIGD +TPRPVTERQALMQSVVASVVAY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides cellulosilyticus TaxID=246787 RepID=UPI001230F4B9 +-qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKYHVGLTVLDKMD +KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI +DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNITDKQILFGTQYKD +FLQATMQETSTGKDKLKGQLPADVIVGHRTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQETDADNAAIIASISKIVYDT- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Candidatus Aminicenantes bacterium RBG_13_63_10 TaxID=1797270 RepID=A0A1F5B941_9BACT +--RLRAQLERLWRNRDGTAGIAVKHLESGREL-LINADDLFPLASVFKLPVLVELMAQVR +EGRLSLEDEIDLVPADLHLGSGVLADLVAPGLSVRNLILLMMTVSDNSAADLLLAKV-GV +ENVNRRLRGLGIEGISVSRSCQELILSFSLQEEDRSAPRAMNVLLERVFRKNILDEASCQ +TILDIMAKCQTGAGRIKGRLPSGTEVAHKTGTLS-GSFNDCGIIFLPDGGHVALSIMTKD +FHMRSADIESLIAETAKFVYDFf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf230 TaxID=1735694 RepID=UPI0009E9CE1D +------------------------------------------------------------ +---------------------------------AAKVMELMIVHSDNEATDQLLAALGGP +VAIQQWLSSHRITGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLAAQSRQ +FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG +GR----DRQPVIAEVSRAIYDYf +>[subseq from] Beta-lactamase n=2 Tax=Sphingorhabdus sp. 109 TaxID=2653173 RepID=A0A653JK83_9SPHN +--ALVQEIEQLWRTFPGKTGIAIKRIDGEWEF-GHRIDEYFPQQSVSKLWVAMTMLDKID +QGRASLSDPIRIGKEDLTLHQPMAVEVEREGKSVYTLLEKALASSDNTANDALLRHAGGP +EAVRKFIDKNNLGKIRFGPGERLLQAAYLADPVDGASPRAIVHALDKLARGELLSANSTK +LLQSILKRTRSGPNRLKAGVPAGWEFLHKTGTGQATGYNDIGIMTAPDGTRYAVVVMLGD +TTASIPERMRMMQAVTRAVGR-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. LMO-1 TaxID=2681549 RepID=UPI0012E6F584 +---LLSEIERLGRGFDGVVGIAVRDVQAGWSV-SWNGTGRFPQQSVSKLWVALTLLDAAD +HGVLRLDDPITVRRTDLTLHQPVRAMMGPDGTSIRNLLTIAMTQSDNTANDVLLKRVGGP +GAVRAFFTRAALPGIAFGPGETLLQSRYLADPMDGAQPEAIAAALARLRKGDLLSPSSTQ +TLLSIMASSKTGPQRLKGGLTEDWAFAHKTGTGQATGYNDVGLLTAPDGRTFAVAVMIAS +TRQPIPVRMRMMQGVTRAVI--- +>[subseq from] Serine hydrolase n=1 Tax=Chroococcales cyanobacterium IPPAS B-1203 TaxID=2049454 RepID=A0A2G7GTP6_9CHRO +--SLKTTVEQLAAQKNLLPGVFFVDLDTGGYL-DVNGNTTFAAASMIKVPLLVAFFQDVD +AGKIRLDESLTLKKELIGGGSGDMQKPLETKFTALETATKMIVISDNTATNLLIERMGGV +AALNERFLSWGLTATQIRNLLPDLEGT------NTTSPKDLAHLMALVNEGDLMSMRSRD +RMLDIMQRTVT-NTLLPRGLGEGATIAHKTGDIGS-LVGDVGLVDMPNGKRYIAVAMVKR +PHND-GRAQELIRQISRAAYQE- +>[subseq from] Beta-lactamase n=1 Tax=Alistipes sp. CAG:157 TaxID=1262692 RepID=R5X4P2_9BACT +-tELEQALRTLVERKRAETGIAVI-LNGTDTV-TVNDAGRYPMMSVFKFHQALAVADFLD +RNGLPLSTPLPIWESDLLPYSPLRDAYPQGGMSIGELLVYTLQLSDNNACDLLFRYIGGP +TAADRYIRTLGIEGFAVEATEEEMHRDLTACYRNWSHPLDAARLLEMLITRPLFRDASQE +FIIRTMTECNTGPERLPKPLATGAVIGHKTGSGDRNGTNDIGFVQLPDGRHYTIAVFVKD +SQESLQETERIIAEASDIVYRY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Chryseobacterium gleum TaxID=250 RepID=A0A1S7SKH9_9FLAO +---LEQKINSILKNKKATVGVSVLGFENGFKY-DKNGDKKLPMQSVFKFHIAAAVLNAVD +QGKLSLHQKIMLNPSNLLEWSPLRDKYPAGNIPLSEVIEYTVAKSDNNGCDILLRLLGGT +QVVQKFMDSKGVKGFQIKYNEEDMHKDWNVQYENYSTTKSAADVLKKLYDGKLLSKKSTD +YLMKVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYA------- +----------------------- +>[subseq from] Penicillin-binding protein n=1 Tax=Nostoc piscinale CENA21 TaxID=224013 RepID=A0A0M4SVF8_9NOSO +---LKNAVQNLAATTDLTPGIFLVDLDNGGYV-DINAAVGFPAASTIKVPILVAFFQDVD +AGKIRLDEMLTMQQDMVAGGSGNFQKPIGTQYSALEVATKMITISDNTATNMLIARLGGI +DALNQRFRSWGLTTTVIKNKLPDLQGT------NITSPKELGNLMAMVNQGNFVSLRSRD +IMLDIMRRTER-DHLLPSGLGAGARIYHKTGDIGT-MLADTGLVDIPNGKRYIISVMVKR +PNND-PRAEKLISSISRITYE-- +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia ursingii TaxID=1756150 RepID=UPI00099A52B1 +-sQLKKTLESIISGKKAIVGISVMSPDEKEIT-GINANQMLPMLSTVKFPLALAVLYEVE +KGKLSMNQKLFIKKEELLSWSPFKEKYPAGNITLEEALKWTVSYSDNNLTDILIRLIGGP +ETVQEFMDS---SSFLIKNDEEGMHKDWDSQFINKITPNFAVLLLQEFSNGKILNKTNTK +WLYNAMLNNVSGKKRLKGNLPTGVKVAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDNSEKIISDIGRAAYDYy +>[subseq from] class A beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=UPI000E489485 +-qNMTREIEKIIKGKQASVGVAIIH--NDDII-TIANEDKYPTMSVFKFHIAVTALKKME +AENIPLDEMVYIKQKEMLKYSPLRDKYPDQGISYRDIIKYTVSISDNNTCDWLIRFVGGI +DEVDSYIKSLGIKDMNFTETEESMHTDIMLCYNNWSTPLAIAQLLKKLHTENILTKEHFA +FLETAMLDCVSGKNKLIAGLPNDIKFGHKTGRSNRTSEGDAGVIYLPNGEKCYIVVLIKD +SRESDDDNAKIMADISNVVYRH- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2D6SWQ8_9PLAN +--ELKALLAPLIEAHQGKVAIAIKHLETSETF-DHRADEPMPTASLIKFPVMAEAYRQAE +QGRVELEGLIALREDDKVPGSGILTTHLSAGLSLRDAIRLMIAYSDNTATNLTLEAI-GI +RSTAEFMESLGMPNTKIHAKVFRRESVFPQRSRGSTTAAETLRLYELLHQRKLVSAAASD +KMRDHLLHCTD-DEKMARLLPPGTKVAHKGGAVSR-ARCDAGIIYSPSG-PLVVCVMTSE +NEQPENAGSRLCADVARVAFEHf +>[subseq from] class A beta-lactamase n=1 Tax=Bacteroides TaxID=816 RepID=UPI000E52BBF2 +-qNMTQEIEKIIKGKQASVGVAIIH--NDDII-AIANEDKYPTMSVFKFHIAVTALKKME +AENIPLDKMVYIKQKEMLKYSPLRDKYPDQGISYRDIIKYTVSISDNNTCDWLIRFVGGI +DKVDSYIKSLGIKDMNFTETEESMRTDIMLCYNNWSTPLAIAQLLKKLHTENILTKEHFA +FLETAMLDCVSGKNKLIAGLPTDIKFGHKTGRSNRTSEGDAGVIYLPNGEKCYIVVLIKD +SRESDDDNAKIMADISNIVYRH- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. KC8 TaxID=1030157 RepID=UPI00111055E3 +--ALETRVAELGRAFPGSVGIAVRDVTTGWSV-GYNATRLMPQQSVSKLWVAITVLDAVD +RGAIKLTEPVVVRRENLTVHQPVRAMMGKDGTTYGDLLRIALTQSDNTCNDMLMRRAGGP +DAVRSMISRKGLGQIGFGPGETLLQSRYLADPMDGASAAAIAAALARLERGELLSRGATR +TLIGTMRDSRTGPQRLRAGLAPGWSLAHKTGTGQATGYNDVGLVTAPDGRTYAVAVMIAS +TRQSIPVRQRLMADVVRAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium 13_1_40CM_55_7 TaxID=1805079 RepID=A0A1Q7F6S9_9CHLR +-qKLESTINDIDRSLDGVIGVAILDLTSGQKF-LLHADEVFPQASSIKIAVLAELYHQAQ +TGKLKLNDLYTVQASDLVPDSDIMGGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GM +ENVDGLMTSLGLTRTRLRRKMMDLKAA-SEGRENISTPGEMMILLENLYRGKVLNKEMTE +DFFKVLSTHKS--SFIPRELPEGLKIANKPGELER-VRNDSGVVFAEKR-PYVICVMTTY +LQR-ERDGEEAISRISLAAYRMf +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium GWC2_64_44 TaxID=1797935 RepID=A0A1F9TFA4_9BACT +--NMTASLDKLASGYRGHVGIYLKDLNSGRVW-QHNPDRLFPSASLIKVPIMVSILSKIK +SGELSLETRMKLTRRDRAGGSGSLKWAREGTLSVTEILFKMITESDNTATKMLIANA-GI +DYLQRAFGELGLVHTGIFQEGMSLASG-RVERENYTTPREMAGLLERIYLGEIVDAASSE +YMLDVLKHNNKSRTRLRKALPPGWELGHKTGLLRR-SCHDVGIVFSPRGD-YVIAVLTGE +VP-DYASAKNFIARVARSTYEYy +>[subseq from] Penicillin-binding protein, transpeptidase n=1 Tax=[Oscillatoria] sp. PCC 6506 TaxID=272129 RepID=D8FTX3_9CYAN +---LKAEIDKLAAQNNFTPGVFIVDLDTGGYA-SVSSDAAFAAASTIKVPILVAFFQAVD +EGRVRLDQVLTLRPEHIASGSGELQDSPGTKYTALEVATKMIAISDNTATNMLIELLGGA +EALNQQFQTWGLTVTAIRNNLPDLAGT------NTTSPKELVNLIGQINQGGLVSLRSRD +RLLYIMRQTQN-DSLLPRGLGEGAIIAHKTGNINS-LVADAGMVDMPSGKRYLVAVMVKY +AK-NEKGADKLIRDISRTTYEYf +>[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI0014473738 +-----NTLQTLTTNSDFTPGVFLLDLDNGGYV-DINSNTSFSAASTIKIPILIAFFQDVD +AGKIRLDEMLTLEKEMMVGGSGNMQYTPGSKYTALDLATKMITISDNTATNMLVAKLGGQ +EALNGRFRSWGLTATMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNVVSMRSRD +LMLNIMNRTER-DNLLPAGLGKGANTYHKTGDIGT-MLADAGLVDVPTGKRYIAAIMVKR +PNND-PRAAKLISSISSAAYQHf +>[subseq from] Class A beta-lactamase n=1 Tax=Coprobacter sp. TaxID=1941478 RepID=A0A316SPR3_9BACT +-qNLTQEIEKVIQDKQASIGVAVMY--GDKTF-TVANHKKYPIMSVFKFHIAVTALKKME +TENIPLDSMIYIEPKQIHKFSPLRDKYPNQRLSYRDMIEYTVAHSDNNTCDLLIEFVGGI +KNVDTYIKSLGIKDLNLTETEHDMHENIMNCYNNWSTPLSIAQLLKKVYTENILTEDHFT +FLEKIMLNCSSGKDKLKAGLPADIKIAHKTGHSDRTSEADAGVIYLPNGEKCYIVVLIKD +SRESDKDNAKIMADIANLTFRI- +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Saccharicenans subterraneum TaxID=2508984 RepID=A0A3E2BMM5_9BACT +-kRLRDQLAATRDSLDGVLGLAVRDLSSGQSL-FINENEIFPQASSIKIAILLEVLKQAE +ENRLKLEEFVDLKPESKVGGGPILNYYPSLKISIRDLCVLMVVLSDNTATNLLIDRV-GM +ETVNDRLTSLGLKQTQLRRKMMDLRAA-EEGRENISTPREMLTLLDRVWQGKVLGPEHRQ +LFFDLLSLPKD--SPLQQAVPEGITVADKPGELE-AVRCDSGLVFLKKR-PYIICVMTTY +LAP-TEDGNAVIRKIGRQVYNHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingosinicella humi TaxID=2068657 RepID=A0A2U2J5Y8_9SPHN +---LDARINELGRAFNGDIGIAVKDIQTGWTS-HYDGTTWYPQQSVSKFWVALTALAEVD +KGNLSLATPVTLGRDDLTLHQPIRAMVLSGGTTPNDLLHRAIQQSDNTANDFLLWRAGGP +EAVRAYLDRMNIEGIRFGPGERALQSSYIANPMDGATPLGIVDALARLKKGELLSPSSTA +LLLEIMSNTRTGPTRLKGGLSGGWRLAHKTGTGQQAGYNDIGIVTSPSGHSYAVAVLIRR +TSAPNIQRMRTMQDTVRAIIDY- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacillaceae TaxID=186817 RepID=A0A4U3BDQ2_BACCE +------------------------------------------------------------ +----TLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP +KGYEKALRHMGDRITMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK +ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWP-------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Sphingomonas sp. KC8 TaxID=1030157 RepID=A0A1X9YEH5_9SPHN +--ALETRVAELGRAFPGSVGIAVRDVTTGWSV-GYNATRLMPQQSVSKLWVAITVLDAVD +RGAIKLTEPVVVRRENLTVHQPVRAMMGKDGTTYGDLLRIALTQSDNTCNDMLMRRAGGP +DAVRSMISRKGLGQIGFGPGETLLQSRYLADPMDGASAAAIAAALARLERGELLSRGATR +TLIGTMRDSRTGPQRLRAGLAPGWSLAHKTGTGQATGYNDVGLVTAPDGRTYAVAVMIAS +TRQSIPVRQRLMADVVRAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Porphyrobacter sp. CACIAM 03H1 TaxID=2003315 RepID=A0A2Z2P425_9SPHN +--SFEQRIADLANPAMGRIGVAAIDLATGEEV-MVLGDQLFPMASTSKIAVAATFMELVE +QGRYSLTSEFPLMMPVASASSARAPVRPGQYMPAIDLIEIMITRSSNPATDALLAAVGGP +QAVNAWMQRKGIAPFSINRDIATLVRATHIDTRDAATPRAMVRLLAGLYRGEYLSDESRR +VILSAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGLIECPDGRVIAVAIYVTG +QG-SKLAREERIAAIARALYDGf +>[subseq from] Beta-lactamase n=1 Tax=Nostoc sp. PCC 7107 TaxID=317936 RepID=K9QG58_9NOSO +---LKNTVQNLAATTDLTPGIFLVDLDNGGYV-DINASVGFPAASTIKVPILVAFFQDVD +AGKIRLDEMLTMQQDMVAGGSGNFQKPVGTQYSALEVATKMITISDNTATNMLIARLGGI +EALNQRFRSWGFTTTIIKNKLPDLQGT------NITSPRELGNLMAMVNQGNFVSLRSRD +IMLDIMRRTER-DNLLPSGLGAGARIYHKTGDIGT-MLADTGLVDIPNGKRYIISVMVKR +PNND-PRAEKFISSISRTAYE-- +>[subseq from] HGF-1 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=C8C0E9_9ZZZZ +------DIKEVIQEKKATVGVAILY--QDKIF-TLSDNQQYPLMSLFKFHVTVAVLKKMD +REHIPLDSTVYITREQMHEYSPLRNKYPNQGISLRDIITYTIIYSDNNTCDWLIDFAGGI +KKVDTFIKSLGIKKLNLTETEHSMHENIMNSYNNWSSPLSVVQLIKKIYTDEILSATSFA +FLEETMLNCSSGENKLKAGLPPNVKIGHKTGHSDRTSETDAGVIYLPDGERCYIAVLIKN +SLESDETNARIMADITRVIYH-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingosinicella humi TaxID=2068657 RepID=UPI0011B23140 +---LDARINELGRAFNGDIGIAVKDIQTGWTS-HYDGTTWYPQQSVSKFWVALTALAEVD +KGNLSLATPVTLGRDDLTLHQPIRAMVLSGGTTPNDLLHRAIQQSDNTANDFLLWRAGGP +EAVRAYLDRMNIEGIRFGPGERALQSSYIANPMDGATPLGIVDALARLKKGELLSPSSTA +LLLEIMSNTRTGPTRLKGGLSGGWRLAHKTGTGQQAGYNDIGIVTSPSGHSYAVAVLIRR +TSAPNIQRMRTMQDTVRAIIDY- +>[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=UPI0009998CAB +---VKKTLESIIYGKKATVGISIIGPDTKDVT-QINGDQMLPMLSTVKFPLALTVLHEVE +KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP +ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITSNYATLLLQEFSNGKILNKAHTQ +WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' 210A TaxID=2014529 RepID=A0A235IE17_9NOSO +-kSLEPQIKALMSRYSLKTGMFFLDLDTGDYL-DIGGDRVFPAASTIKLPILIAFFQNLD +AGKVTLQENLTMRRDLVTNGSGSMQERVGKKYTALETITKMITISDNTATNMIIDRLGGA +AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKHYLAAIFVTR +PYKD-TRGRDFIRQVSRLVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. 32-66-10 TaxID=1970437 RepID=A0A258H6U6_9SPHN +--ALTATVDALARDFGGVVGISVRSLEWGWQV-DANGDRRMPQQSVSKLWVAMTVLDARD +KGRLTLDDPVELRREHLTLHQPIATLVVRDGTTVRELLLRAMQQSDNTANDRLLTLAGGP +QAVRAFIAERGLGEIRFGPGERLLQASYVADPVDGAAPSAIALALARLKAGELLSASSTS +FLTNVMSGTRTGKARLRAAVPVGWTLAHKTGTGQTAGFNDIGILTAPDGKAYSVAVMIGD +TPRPVRERQQLMQAVVASVVA-- +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5MKG4_9BACT +------------------------------------------------------------ +-------------------------------MTLGALCAAAIEQSDNTAGNLLLDTIGGP +VGLTNFARSVSDETTRLDRKEPELNSAIPGDERDTTTPAAMCADMQHFLLGNVLSESSQN +QLQDWLPQNETGSLMIRASVPKTWTVGDKTGRCGNGATNDVAIIRPPGRAPILVAIYSIG +STSSADDRAAIVAEPARAVVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Caulobacteraceae bacterium TaxID=1978230 RepID=A0A4Q3TAI9_9CAUL +----------------------------------------FNYCSTFKLFLAAATLERAQ +RGDERLDRAVAISSGDLVSHAPVTGAAVGGHLTIQDLCQATVEVSDNPAANILIREMGGL +DAWRGWLRSIGDADTTIDRLEPGLN--VPDGAKDTAHVDQTVTNLQAVLKEGRLDQAHSA +LLRRWLVDSPTGAGRIKAGAPVGWTVAHKTGTGGGGQVNDIGLLEGPNGQRVFLAIYYDG +PSKPAAEADAVVAEATRIS---- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. MBR 210 TaxID=1881015 RepID=A0A1C0UWE4_9NOSO +---LKNAVQNLAATTDLTPGIFLVDLDNGGYV-DINASVGFPAASTIKVPILVAFFQDVD +AGKIRLDEMLTMQQDMVAGGSGNFQKPVGTQYSALEVATKMITISDNTATNMLIARLGGI +DALNQRFRSWGLTTTVIKNKLPDLQGT------NITSPRELGNLMAMLNQGNFVSLRSRD +IMLDIMRRTER-DNLLPSGLGAGARIYHKTGDIGT-MLADTGLVDIPNGKRYIISLMIKR +PNND-PRAEKLISSISRTTYE-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520JFA9_SPHSX +------------------------------------------------------------ +---------------------------------AAKVMELMIVHSDNQATDQLLAALGGP +VAIQQWLSSHRITGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLAAQSRQ +FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG +GR----DRQPVIAEVSRAIYDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas faeni TaxID=185950 RepID=A0A2T5U9A4_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIVHSDNQATDQLLAALGGP +VAIQQWLSSHRITGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLAAQSRQ +FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG +GR----DRQPVIAEVSRAIYDYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. PAMC26645 TaxID=2565555 RepID=A0A4P7QZ09_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIVHSDNQATDQLLAALGGP +VAIQQWLSSHRITGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLAAQSRQ +FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG +GR----DRQPVIAEVSRAIYDYf +>[subseq from] Putative beta-lactamase n=1 Tax=Erythrobacter sp. NAP1 TaxID=237727 RepID=A3WBM5_9SPHN +--AFEQRLEEIGASLTGTVGIAVQDVETGELY-EFNGDELLPQQSVTKLWVAMAALSQVD +QGDLNLTERVRIGRDDLTLHQPVREIVKARGTNYRDLFERSITRSDNTANDRLLRRIGGP +DAVQQWLDDKGLTGIRFGTDERSKQSGYLADPIDGASANAIASALTKLARGDLLDTDTTR +LLRDTLEQTRSGPRRLKGGAPEGWRVEHKTGTGQQSGYNDVGILTSPDGREYAIAVLIGR +TSEPTPARMEMMQQVTSATAQ-- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. T09 TaxID=1932621 RepID=A0A252DE48_9NOSO +-kALEPQIKALMNRYSLQTGMFFLDLDTGNYL-DIGGDRVFPAASTIKLPILIAFFQDLD +AGKVRLDEKLTMRRDLVTNGSGVMQERVGKKYSALETVTKMVTISDNTATNMIIDHLGGA +AKLNQRFRSWGLKDTVIRRLLADLRGT------NTTSSQDMARVLALLVNNKLVSPSSKE +QALDILRHTSI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVKR +PYKD-SRGRDFIRQVSQLVYNY- +>[subseq from] Beta-lactamase class A n=1 Tax=Undibacterium pigrum TaxID=401470 RepID=A0A318JEI3_9BURK +----QNVIESIAIDSGGRLSASLLVLETGQSL-WILPDQAAPMQGVSKLPVVMAALAAVD +KNKLKLEQKVTVSKEELIAASPLRDEHPDGNISLKELMHHAIVDNDGTANDVLLRLLGGP +TAVMQYLAQLEIQDIKVLNTDKEMAKSWNMQYRNTGTPKAMIKLLQALQQGKALSPKARE +LLLKWMTDAETGAARIKALLPAGTAVAHKAGSSATAAHNDVGIVTLPNGHHMVVAVFLTD +SKAPHASRDLTIAKITKLGWDAw +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Microcoleaceae bacterium UBA10368 TaxID=2055793 RepID=A0A355CJJ6_9CYAN +---LKTQIQILATENNLTAGIFLVDLDNGSYL-NLNGDATFASASTIKLPILVAFFQAVD +EGKVHLDQMLTLGAEHIVGGSGEMQDSPGRKYSALEVARKMIVVSDNTATNMMIELLGGA +EVLNQHFATWGLSATVLRNKLPDLEGT------NTTSPKDLINVMAQVDRGNLVSVKSRD +RILQIMRQTQN-DTLLPKGLGEGATIAHKTGNINT-MLADAGMVDLPNNKRYVVAVMVKH +SPETEKAAGSLIRDISRMSYRY- +>[subseq from] serine hydrolase n=1 Tax=Dolichospermum planctonicum TaxID=136072 RepID=UPI0014432547 +---LKNTLQSLAANSDLTPGVFLLDLDNGAYV-DINGNTSFPAASTIKIPILIAFFQDVD +AGKIPLDEILTLEKEMIVGGSGNMQYAPGSKYTALDLATKMITISDNTATNMLIAKLGGQ +EALNGRFRSWGLTTTMIRSPLPDLQGT------NTTSARELGNLISMVNQGNVVTMRSRD +LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-LLADAGLIDVPTGKRYIAAIMVQR +PNND-PRAAKLISSISSSAYQYf +>[subseq from] Beta-lactamase n=2 Tax=unclassified Novosphingobium TaxID=2644732 RepID=A0A0N1AJW0_9SPHN +--AIQQRVASIAAAARGRVGVAAMDLDGGGQV-LINGDMPFPMASTAKVAVSATFLQMVE +QGRFRLDQPLPMMMPVPEARNLVAMVRPGPVYTAQTLIEKSITRSDNHATDGLIAAVGGI +GAVNRFLTQTGISGQHLDHTMATLVRARAIDTGTSSTPRAMIALLSAIDRGGALGPQARA +VLLDTMTRTSTGRNRIRAGLPEGVLLAHKTGTLA-GVTDDVGIVRMPDGRHLAMAIFVAG +PE-NHTAQAGMIARIASALYTGf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. URHD0057 TaxID=1380389 RepID=UPI00068779C1 +------------------------------------------------------------ +------------------------------GVSARSLMKRMLIHSDNRATDILLKDLGGP +SALHDWLQQSGVNGLRVDRTIAQLLSAKRWDRRDSSTPTAMVDLLRRIYRAELIRPKSRD +YLLDLMAQCETGKNRMKALLP-GVPIEHKTGTLD-GLTDDVGFISMPDGHRVAVAIFTRG +GS----DRPRAIAQAARAIYDGf +>[subseq from] Serine hydrolase n=1 Tax=Alphaproteobacteria bacterium HGW-Alphaproteobacteria-16 TaxID=2013662 RepID=A0A2N3DEN8_9PROT +--ALTASIDALTREFGGVVGVSVRSLDWGWQV-DANGNRPLPQQSVSKLWVAMTVLDARD +KGRLTLDDPVTLTRENLTLHQPIAALVVRDGTTVRELLLRAMQSSDNTANDRLMLLVGGP +EAVRAFIRDRGLDGIRFGPGERLLQASYIADPPDGATTSGMAMALARLKAGELLSPGSSN +FLINVMQGARTGRARIKAGTPADWKWGHKTGTGQTAGFNDVGILTAPDGKSYAIAVLIGD +TSRPVPARQQLMQAVVASVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Cyanobacterium aponinum (strain PCC 10605) TaxID=755178 RepID=K9Z2J0_CYAAP +--ALRSKFDTLRAKYQLEPGAFFVDLDNGAYV-NYNGIAPFPAASTIKIPVLVAFLQDID +EGKIYLDEKLTMTEANRVPHSGNMQYQPGTQFTALYTATEMIINSDNTATEMIIERLGGK +DELNKRFQEWGLENTVIRNLLPDLEGT------NTTSPRDLGILLAKVNQGDLLSVRSRD +RLLEIMRRTKT-QTLLPQGLENNAIIAHKTGDIGT-VLGDAGIIDMPTGKRYIGAVLVKR +PHND-YSARTLIQEISRTAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Dolichospermum compactum NIES-806 TaxID=1973481 RepID=A0A1Z4V313_9CYAN +-------------NADLMPGVFLLDLDNGNYV-DINTNTSFAAASTIKIPILIAFFQDVD +AGKIRLDEMLTMQKEMIVGGSGNMQYTPGSKYTALDVATKMITISDNTATNMLVAKLGGQ +EALNGRFRSWGLTTTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNVVSMRSRD +LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR +PNND-PRAAKLISSISSAAYEHf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides plebeius TaxID=310297 RepID=A0A414X613_9BACE +-qELYTNIYQFISQQKAEVGVAIIA-DGKDTV-TIENNRRYPLMSVFKLHQALAVGDYCK +RHQLSFDTLLTVDSTDLQPYSPLRDRYPHGGFSLKQLMEYTLHLSDNNACDILFKFTGGP +AVTDRYIRSLGINDFSIQYTEDDMHQDLNLGYENWSTPLATAEVIEALLTRTLFDKPHQE +FIKEALVTCQTGTSRIVHPLQKQVTVGHKTGTGDRNAINDAGFVQFPNGHRYTLVVFVKD +SQESMEDTEAIIAQISEMVYQAf +>[subseq from] Serine hydrolase n=1 Tax=Cyanobacterium aponinum IPPAS B-1201 TaxID=2047986 RepID=A0A2G3PBP3_9CHRO +--ALRSKFDTLRAKYQLEPGAFFVDLDNGAYV-NYNGIAPFPAASTIKIPVLVAFLQDID +EGKIYLDEKLTMTEANRVPHSGNMQYQPGTQFTALYTATEMIINSDNTATEMIIERLGGK +DELNKRFQEWGLENTVIRNLLPDLEGT------NTTSPRDLGILLAKVNQGDLLSVRSRD +RLLEIMRRTKT-QTLLPQGLENNAIIAHKTGDIGT-VLGDAGIIDMPTGKRYIGAVLVKR +PHND-YSARTLIQEISRTAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. AE3 TaxID=2594473 RepID=A0A516IQS1_9SPHN +------------------------------------------------------------ +------------------------------GVSAARLMDAMMTRSDNHATDLLLRDLGGP +ATVQAWLRQQGLEGLRIDRNIARLLADKRSDIRDSSTPRAMVDLLKRIDQATLLSRSNSD +YLLDMMARCRTGKNRIRALLPSGTPVQNKTGTLNR-YSSDVGFITLPDGRRLAVAFFARN +TN----NGPSTIAWAARTVYDGf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. PP-CC-3G-468 TaxID=2135656 RepID=A0A4R1U727_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIVHSDNQATDQLLAALGGP +VAIQQWLSSHRITGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLAAQSRQ +FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG +GR----DRQPVIAEVSRAIYDYf +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas aquatilis TaxID=93063 RepID=A0A511Q662_9SPHN +--RLTAAIDSLARNFDGKFGIAIRAVDDGWTVtSPGARTRMPQQSVSKLWVAMTLMDLRD +QGKARLDDPVVVRDQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP +SAVRAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALARLARGELFTETSTR +ILLDTMGASVTGRARLRAAIPAGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +SRRPIRERQQLIQAVAAAVAN-- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter vulgaris TaxID=291985 RepID=UPI0013717C30 +-eQLEAELRTIGESFAGEVGIAVSEAESLATM-SYAGKKPFPQQSVSKLWVTLTALDLVD +EGALELAEPVTIRREDLTVYQPIREIVKARGTDYGELIQRAITQSDNTANDRLLRRVGGP +QAVEAFMRRNQITGVQFGTDERTKQSTYLADPMDGASARGMSKALARLARGDLLSESSTE +LILSTMEETRSGPRRLKGGVPGGWTFGHKTGTGQQSGYNDVGILTAPDGTHYSLVVLIGQ +TRVSYAERMAMMQEVTRAVVRH- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium EhC05 TaxID=1849171 RepID=A0A1B6Z7Q7_9SPHN +--ALERELAEIWRTFPGKTGIAVKRIDGNWEI-GHRQNEWFPQQSVSKLWVAMTLLDKVD +RGRASLSDAIRIGKEDLTLHQPMAVEVEREGKSVYTLLDKALASSDNTANDALLRHAGGP +EAVRNFIDKNDLQKIRFGPGERLLQSAYLADPIDGASPLAIVRALSKLARGELLSENSTR +LLQSILTRTRSGPNRLKAGVPAGWKFLHKTGTGQATGYNDVGIMTAPDGTRYAVAVMLGD +TTASVLQRMRMMQAVTRAIG--- +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis macrogoltabida TaxID=33050 RepID=A0A0N7GSY1_SPHMC +---LSDRINGLWRAFPGKTGIAIQRIDGEWEF-SERGGDLFPQQSVSKLWVTMAVLDAVD +QGRLRLDQMVRIGPDDLAVHQPLAARVLAEGMSVRDLIETAITHSDNLANDSLLRTVGGP +DAVRRFIANKGLGSIRFGPGERLLQSNYLANPVDGASPSAIASALTRLARGTLLSPESTE +YLLGVMSRTKSGPRRLKGGLPPGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGN +TTSPIPARMSLMQAVSGAVAE-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas crusticola TaxID=1697973 RepID=UPI000E2249B5 +--TLAEQLATIAAGGNGRIGIAATDLDTGESF-TYAARDPFPMASTVKVAIAATYLAGVD +RRRFDLDQLYR---------------RGGTVLTARRLIELMLIRSDNGAADILLQAVGGT +QAVNNWLNRAGIRGQRMDRTIARLVLAFVGDARDTSTPTAMVGLLAKLHQGVLLSPDSTR +YLFEVMGRCVTGPHRIKGMLPAGTPVAHKTGTLA-GVSDDVGIVSLPNGHRLALAIFAKG +MR-SEWERDRSIAQLARLLYDRf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Myroides marinus TaxID=703342 RepID=UPI0007421CBA +hqELNNKIKSVISNKNATVGVAIIY-DAKDTL-TVNNDHKYPTMSVYKFFQALNILDYMD +KHNISLDTEIYIKKEDLKEYSPLRDKSPKGEMSLRELIQYTASHSDNNISNLFFRSLIGP +KMTDLYFRSLGIHNFEIVSSEETMSLDFSNQYQNWITPLEATRILEMFRKEELLSPDYNN +FLRQAMIDTKSGQDKVKALLPKNTVVVHKTGMSFRAADNDLAIVYLPNGKQFSIAVFIMN +SKESDKTNASIIAEISKLAYDYf +>[subseq from] serine hydrolase n=1 Tax=Halothece sp. (strain PCC 7418) TaxID=65093 RepID=UPI0012372B4B +--ALKETFKRLAREKQLKPGAFIVDLESGQYV-SLQGESQFSAASMIKVPVLIAFFKAWD +EGRLELDEPLTMTEEVKAGGSGNMQEAVGKQYRALETAAKMISISDNTATNMLIQRLGGK +ETLNELFAAWGLEKTRIRNPLPDLDGT------NTTSPKELVKLLARLNNGELVSARSRD +YILQIMRTTRT-RTLLPQGLDKNATIAHKTGDIGS-LVGDVGIIDRPSGKRYLAAIMVER +PHND-RNANELIRRYSRAAYQYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas hengshuiensis TaxID=1609977 RepID=A0A2W5C389_9SPHN +--ALVAAVNELARGFDGKLGIAVRSIDQDWQV-ATNGDIALPQQSVSKLWVAMTVLDAAD +QGRLRLDDPVRVTREDLTLHQPIAAMVRGDGATVGELLQRSLTQSDNTANDRLLRLVGGP +EAVRGFIRRKGLGTIKFGPGERLLQSAYVADPPDGAAPVAVTAALAKLKRGAILSAPSTR +YLIDTMESAKTGKQRLAGAVPPGWRFGHKTGTGQTAGYNDVGILSAPDGRSYAIAVMIGD +TPRPVRERQALMHAVIASVI--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas taxi TaxID=1549858 RepID=A0A097EI50_9SPHN +--QLTSAIDALARNFDGKFGIAIRAVDAGWTVtSPGARIRLPQQSVSKLWVAMTLMDLRD +QGKARLDDPVVVRPEDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP +AAVHAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALSRLARGELFTETSTR +ILLDTMGASVTGRARLRAALPAGWQIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +SRRPIRERQQLIQSVAAAVANY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520DNB5_SPHSX +--QLTGAIDTLARDFDGKFGIAIRAVDEGWTVtSPGARTRLPQQSVSKLWVAMTLMDLRD +QGKARLDDPVVVRPEDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP +AAVRAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALSRLARGELFTETSTR +ILLDTMGASVTGRARLRAALPTGWQIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +SRRPIQERQRLIQSVAAAVAS-- +>[subseq from] Class A beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1W5MZT1_9BACT +-aELEQALRTLAEGKRAETGIAVI-LNGTDTV-TVNDAGRYPMMSVFKFHQALAVADFLD +RNSLPLSTPLPIRESDLLPYSPLRDAYPQGGMSIGELLVYTLQLSDNNACDLLFRYIGGT +TAADRYIRTLGIEGFAVEATEEEMHRDMAACYRNWSHPLDAARLLEMLITRPLFRDASQE +FIIRTMTGCRTGQERLPKPLATGAVIGHKTGSGDRHGTNDIGFVQLPDGRHYTIAVFIRD +SQESLQETERIIAEASGIVYRY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium CG_4_10_14_3_um_filter_58_15 TaxID=1974093 RepID=A0A2M7LG03_9SPHN +--ALVREIEALWRTFPGTTGIAVKRIDGAWEF-GFRSDEYFPQQSVSKLWVAMTLLDKID +QGQASLSDPIRIGKEDLTVHQPMAVEVERNGKTVYTLLEMALASSDNTANDALLRHAGGP +DAVRRFIAKNSLGKIRFGPGERLLQSAYLADPVDGASPMAIAHALDKLARGQLLSDNSTK +LLQSILKRTRSGPNRLKAGVPAGWEFLHKTGTGQSTGYNDIGIMTAPDGTRYAVVVMLGD +TTASIPERMRLMQAVTRAVGR-- +>[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SIJ0_9BACT +------------------VGVAVM-TGRNKIL-LHNNKMNYPLLSVFKFHVALAVLDKMN +KQGTPLDHIVHVKASQLQPYSPLRQKYPNQDISLGELLRYSISLSDNNACDILIEYAGGI +GHIHQYINKLGICNFNLSETEDSMHRNPSKTYLNWSTPAEMVRLLEIADEKELFDPIYRD +FLWNTMIATSTGSNKLKGLLPSNVIVGHKTGSSDRNADNDAGVVIMPDGKKYYIAVFVMN +SRETDDENAAIIARISRMVYDEy +>[subseq from] Beta-lactamase class A n=2 Tax=Pedobacter caeni TaxID=288992 RepID=A0A1M4V334_9SPHI +--QLQERIKHIIDTAGGKIGVGVKGMDFKGGF-VINGNHGYPMMSVFKFPLAFAILDKVD +KGELKLSQKFHMPKETLDTWSPMVKDFPNQDMTLADLLTYTVSKSDNNACDFLYTKVGGP +AAVNQYLHNAGVKGISIVYTEGEMEKDWALQYKNWCKPAASLQLLQLLYHQKLLSKSSND +FLIQIMRELPDWGKRITVLLPPTTELIHKTGASGMAAFNDIGIVTLPNGKHIAISVFASD +FKAPKERGINVIAAISKEIWDYy +>[subseq from] class A beta-lactamase n=1 Tax=Actinospica acidiphila TaxID=304899 RepID=UPI0013CD078F +------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP +--GARLDERISYGTADLVPYSPVTEKHTGQGMTLRELCDAAVRYSDNTAGNLLLRDIGGP +RGLTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIA------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Kamptonema TaxID=1501433 RepID=UPI0002EAC056 +---LKAEIDKLAAQNNFTPGVFIVDLDTGGYA-SVSSDAAFAAASTIKVPILVAFFQAVD +EGRVRLDQVLTLRPEHIASGSGELQDSPGTKYTALEVATKMIAISDNTATNMLIELLGGA +EALNQQFQTWGLTVTAIRNNLPDLAGT------NTTSPKELVNLIGQINQGGLVSLRSRD +RLLYIMRQTQN-DSLLPRGLGEGAIIAHKTGNINS-LVADAGMVDMPSGKRYLVAVMVKY +AK-NEKGADKLIRDISRTTYEYf +>[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis macrogoltabida TaxID=33050 RepID=A0A0P0D6Q1_SPHMC +---LSDRINGLWRAFPGKTGIAIQRIDGEWEF-SERGGDLFPQQSVSKLWVTMAVLDAVD +QGRLRLDQMVRIGPDDLAVHQPLAARVLAEGMSVRDLIETAITHSDNLANDSLLRTVGGP +DAVRRFIANKGLGSIRFGPGERLLQSNYLANPVDGASPSAIASALTRLARGTLLSPESTE +YLLGVMSRTKSGPRRLKGGLPPGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGN +TTSPIPARMSLMQAVSGAVAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. BK036 TaxID=2512122 RepID=A0A4V2FM90_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIIRSDNQATDQLLAALGGP +VAIQRWLSSQNIPGIRMDRSIAQLLRGHLADIKDVATPIAMVTLLNKLDNGTVLAPQSRA +FLLGLMGRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG +GR----DRQPVIAEVARVIYNRf +>[subseq from] Beta-lactamase class A n=1 Tax=Bhargavaea ginsengi TaxID=426757 RepID=A0A1H6UBS8_9BACL +--QLQEKVERILEGTDATFGVSIKHLQSGEEV-RIRADEPFQMASVFKVPIVLTLFEQVH +EGQIDLTTRIALTEEDRVPGSGILQELDPGLVTIKDLATLMTIVSDNMATDVLLGML-GK +DAVGDTMRRLGAENISIVHSCWELLSMRKDQENNVCTPDTMTGLLVKLAEGAFINPAVSE +AVLDILYRQQL-NDRIPARLPSGTRVAHKTGTIAS-AVNDSGIIELPGGGPLIISIFSAG +NE-TTQGGEAMIARIAEAAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Bathyarchaeota archaeon TaxID=2026714 RepID=A0A524A9M6_9ARCH +---LLDKISGVEKGFGGTLGVAVKYLGSGESA-SMNGDELFPTASVFKIPVIVEFYRQLE +SGAVSLDEKITLMDGDKVPGSGILKELSEGLISYSDLLELMIVLSDNTATDLVVERV-GK +ERVNATLRELGLEKTLVVADCRDILFSLGVEENDVTTPDEMLRLLEMIVDGEAASRESCD +AILEIMGKCQTGIYRISKYLPEEIEFAHKTGSLP-GVRNDVGIVTHKTGQRYIICCFTKD +AE-DVYSAEEVIARVSEVAYDYf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. SYSUP0001 TaxID=2303576 RepID=UPI000E56F659 +------------------------------------------------------------ +-------------------------------RSARALMEAMMIKSDNVATDLLLANLGGP +AKLQQWLRERHVSGMRVDRTIAQLLAAKRWDVRDSATPRAMVELLRRIDKGELLRPSSRA +YLLDLMARCKTGRNRMRALLPASAQVQHKTGTLNN-YTSDVGFITLPDGRRLAVAFFARG +GA----NRPATIAMAARTIYDGf +>[subseq from] Uncharacterized protein n=2 Tax=Mastigocoleus TaxID=996924 RepID=A0A0V7ZMD9_9CYAN +---LKASLQSMANQNSIRPGVYLIDLDDGRYV-NVNATLSFPAASTIKIPILVAFFQDVD +NGKIRLNEVLTMEKDDMVGGSGDMRNQPAGTYKALEVADKMMTISDNTATNMLIKRMGGM +QALNQRFRRWGLTHTALRNPLPDIEGT------NTTSPKDLGDVMAMVSRGRLVSMQSRD +RILAIMRQNTR-RHLLPTGLGEGATIANKTGYIGK-MLGDAGLVDLVTGKRYTIAVMVER +KVKDDPSAEKFIKSASRQAFE-- +>[subseq from] Beta-lactamase n=2 Tax=Phenylobacterium zucineum TaxID=284016 RepID=B4RBD1_PHEZH +-kALQDELSALALAYGEEVGIAVTDLDQGWTA-GVDPDGVYPQQSVSKLWVAIAVLKAAD +EGRLELDRTVLLTDADRSVFQPVAYNIGPQGTTIEALLRRAIVQSDNAANDRLMREVGGP +EAVAEALDGLGLKGVTVGAYERDLQAAYLAEPMDGAQPAAIARALAALKKGELLSPASTD +RLLTLMEEVRTGPRRLKGGLPPGWSIGHKTGTGQRGGINDVGLLTAPDGRIYAVAVMMRR +TWKPVPQRLAFMQAVSRAVAAEw +>[subseq from] Beta-lactamase class A n=2 Tax=Dactylococcopsis salina TaxID=292566 RepID=K9YPP7_DACSA +--TLKQTLQRLGSQSQLNPGAFIVDLDSGEYV-SLQGEKAFSAASMIKVPILIAFFHAWD +EGKLKLDERLTMTEEVKAGGSGNMQEAVGTEYLALETAAKMIIISDNTATNMIIKRLGGK +EALNQLFAEWGLEQTRLRNPLPDLEGT------NTTSPKELVELLAKLNQGKLVSARSRD +PIFRIMRETKT-RTLLPQGLGEGASIAHKTGDIGS-LVGDVGIIDRPSGKRYLAAIMVER +PHND-RAANELIRQFSRETYQYf +>[subseq from] Beta-lactamase class A n=2 Tax=Oscillatoria acuminata TaxID=118323 RepID=K9TTS6_9CYAN +--TLKEKLQAMAAEHELTPGVYAIELDTGAYL-DLNGSQRFSAASTIKVPILIAFFQDVD +AGKITLNEMLTMKEEHIAEGSGDMQTEPGTKYSALETATKMSQISDNTATNMLIERLGGA +AALNQRFASWGLSNTAIANPLPDLAGT------NTTSPQDLVQVMGLVERGQVLSLRSRD +RLLKIMQGTVN-NSLLPQGLGSGAAIAHKTGDIGT-AISDAGLVDMPNGKRYLMAAIVKR +PHND-PEAEELIRQMSQVVYQSf +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A525HIC8_SPHSX +---LVALVQSLTRDFGGKVGIAVKSLDDDWMA-TSNGDLKLPQQSVSKLWVAMTVLDARD +QGKLTLDDPITVRREDLTLHQPIAALVKDAGTTVGELLQRALTQSDNTANDRLLQFVGGP +TAVRAFLAKKAIADIRFGPGERALQSRYIADPVDGAAPRAIATALARLKRGELLSPSSTQ +YLIGTMESSRTGKQRMRGAVPEGWTFGHKTGTGQTAGYNDVGFLIAPNGKAFTIAVMIGD +TDKTIAERQALMQAVVLGVVT-- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WN54_9BACT +--ELTKQIAALCNDSQGEIGVTVIHVESGRTV-NFEGEKKLPLYSVFKLPLALEVLKRVA +EKKISLDQKIHVAPADVAPGSQFNADLWRKPKTVAELLEFSIVRSDNTSSDQLLQLVGGP +AVVTERMRTLGFPNIDIVSTVREYATS--QGKPNLATTANLARLLSRLQKGELLEPSHLS +LLLGFMERARTGERRLRASLPLGTTVAEKTGSGAD-STNDVGLITLPDGGHLAMAVLIHN +SKLTAEAQERLIADLARKAYDAf +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI0007D8C1BC +---WQQAVEDVLKEAPGIFGIAAMHLETGETA-GHLDEELFQLASAFKIPIMVTMMREVE +AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELIGGI +DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE +LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEEKGMIGITALSR +GVIDKEAAELTIARVAKAIYE-- +>[subseq from] Serine hydrolase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A249MSG3_9SPHN +-----SVVRNLGQSFRGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD +RGKLRLADTTTITRNDLTLHQPTAAMVGTKGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPAAIVQALARLKQGDMLSSASSR +LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTVSIPERWALMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Leptolyngbya valderiana BDU 20041 TaxID=322866 RepID=A0A166T6X0_9CYAN +--ALKERLQQVAAEYGLTPGVAIVDVATGDYV-RLSDTMSFSAASTIKVPILVAFFRAVD +AGTVRLDEVLTMEESHIAGGSGYMQYAPGTRYSVLEVASSMIIDSDNTATNMLVDRLGGA +KVLNEQFREWGLTETTIRNPLPDLEGT------NTTTPQELAKLLGQLERGELVSMRSRD +RMMRIMSQTAN-DALLPQGLGEGAFVAHKTGNLRS-VLADAGAIDLPNGKRYLMVAIVKR +PDED-DRAADLIRQMSATAYDYf +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingobium TaxID=165695 RepID=A0A560XEG7_9SPHN +-----SVVRNLGQSFRGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD +RGKLRLADTTTITRNDLTLHQPTAAMVGTKGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPAAIVQALARLKQGDMLSSASSR +LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTVSIPERWALMQAVAKAVAA-- +>[subseq from] serine hydrolase n=1 Tax=Anabaena variabilis TaxID=264691 RepID=UPI000F8DEDF3 +----KTAVQNLATASNLTPGVFMVDLDTGAYV-DINSNASFSAASTIKVPILIALFQDVD +AGKIRLDEMLTLQQDMIAGGSGTLKSNPGTQYSALEIATKMITISDNTATNMLISRLGGK +DVLNERFRTWGLATTMIRNSLPDLQGT------NTTSPRELGNLISMINQGNIVSMRSRD +LMLNIMSRTER-DHLLPSGLGQGSKAYHKTGDIAT-MLADAGLIDIPSGKRYIAAVMVQR +PTND-PRAEKLISSISAAAYQHf +>[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. B2 TaxID=2583228 RepID=UPI0011A4A3C0 +-----SVVRNLGQSFRGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD +RGKLRLADTTTITRNDLTLHQPTAAMVGTKGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPAAIVQALARLKQGDMLSSASSR +LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTVSIPERWALMQAVAKAVAA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F1DI12_KLEPN +------------------------------------------------------------ +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGHETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDY------------------------- +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Candidatus Latescibacteria bacterium TaxID=2053570 RepID=A0A3N5WVJ1_9BACT +---VEAEIERIAAEVPGEVGVAAIHLETRRLL-SHNGTDRFPMASVYKVPIAVQALSRVE +AGDLDLEKTLPILPEDHRPGSGHIAEFRSPGLSLRNLLRLSLIKSDNTASDLVLRFAGGP +KAVTKRIRSLGIVDMRVDRSTLQMILIASVDVRDTSTPIAMARLLEKIWSGEALGEEARD +FLLGTMAECN-GSRRLKGMLPPGLEPAHKTGTMGYSTVNDAGIIELPDGGHLAIAVFINQ +AEEDVFELENVIAQITRLLVDFf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. EC-HK361 TaxID=2038397 RepID=A0A5E7XRR7_9SPHN +-qQLADRVSNLIRAFGGKAGVGIRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITLLDQRD +RGLVRMDDPIVVRTQDLTLHQPIAALVKGDGTTVGELMRRALTMSDNTANDRLLSLVGGP +MAVREMIAAKQLGDIRFGPGERLLQSRYVADPIDGAAPLAIADALARLARGELLSETSTR +LLLDTMAASHTGRARLRAVVPTDWQIAHKTGTGQNAGLNDVGLLTAPDGRRYAVAVMIGD +TTHTMRERQQLIQAVGAALI--- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc punctiforme NIES-2108 TaxID=1356359 RepID=A0A367RM87_NOSPU +-kALEPQIKALMSRYSLKTGMFFLDLDTGDYL-DIGGDRVFPAASTIKLPILIAFFQDLD +AGKVTLQENLTMRRDLVTNGSGSMQERVGKKYTALETITKMITISDNTATNMIIDRLGGA +AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR +PYKD-TRGRDFIRQVSQLVYDY- +>[subseq from] Serine hydrolase n=2 Tax=Sphingomonas sp. Leaf10 TaxID=1735676 RepID=A0A0Q4CZR5_9SPHN +---LVSAINALGGGFQGRVGIAVRSIDEGWVV-GHAMDQRMPQQSVSKLWVALTTMNAID +EGKLALTTPVTITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTLSDNTANDKLLNLAGGP +VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLRHGMLLTPQSTN +WLLDTMSHTRTGRARLRAALPAGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD +TARPVPERQQLIQTVVSAIVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Coxiella burnetii TaxID=777 RepID=UPI000D409346 +--SINKKLAALEKTTGGRIGLYAIDTENNVRF-QYRARERFPFCSTAKVIVVSAILKKSI +TDPHFLQQNVVYKKNELVSYSPITKNHINGGITVSELCAAALTLSDNSAANLLIKKLGGL +TAINAFARSIGDKQFELDRLEPQLNSAIPGDIRDTTTPEAMANSLKRLTLGDILAFPQLI +QLQTWLK----------------------------------------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Trichormus variabilis SAG 1403-4b TaxID=447716 RepID=A0A433USU6_ANAVA +----KTAVQNLATASNLTPGVFMVDLDTGAYV-DINSNASFSAASTIKVPILIALFQDVD +AGKIRLDEMLTLQQDMIAGGSGTLKSNPGTQYSALEIATKMITISDNTATNMLISRLGGK +DVLNERFRTWGLATTMIRNSLPDLQGT------NTTSPRELGNLISMINQGNIVSMRSRD +LMLNIMSRTER-DHLLPSGLGQGSKAYHKTGDIAT-MLADAGLIDIPSGKRYIAAVMVQR +PTND-PRAEKLISSISAAAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A517I1E7_BREBE +---WQQAVENVLKEAPGIFGIAAVHLETGESA-GHLDEELFQLASAFKIPIMVTLMREVE +AGRIRLDQRVTLKWEGRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI +DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE +LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR +GVTDKEAAELTIARVAKAIYE-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. EO9 TaxID=2304063 RepID=A0A418YSL0_9SPHN +--RLIAQFQRFASLTDGTVGIVVRDLGTGETL-SLNGDTLFPMASAYKVAVAGRIFAMID +AGALTLDDRLA---------------SPAGPVSVATLVDLMLTRSDNDATDLLVARAGGP +AAVHHWVAGLGIRGLRVDSNTADLLYAFAQDPRDTATPTAMTDLVAAIRTGKALSGRSTV +ALLSIMERCRTGKARLPGMLPPGTLVAHKTGSLN-GTGNDTGVITLPDGRLFAITVFVMQ +DHKGQATRDRIMAEAARATYDYf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium quisquiliarum P25 TaxID=1329909 RepID=T0GYZ5_9SPHN +-----SVIRNLGQSFNGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD +RGKIRLTDTTTITRKDLTLHQPTAALVGSSGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRAFLARRTIKDIRFGPGERLLQSNYLANPPDGAAPSSIVKALAKLKEGEMLSPASSQ +LLMSIMSQAKTGPQRIKGGVPAGWKYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS +TTEPIPVRWQLMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Microcystis wesenbergii Mw_QC_S_20081001_S30D TaxID=2486245 RepID=A0A552J9C0_9CHRO +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +EALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSANIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_1_20CM_2_65_9 TaxID=1803428 RepID=A0A1Q8AJ58_9BACT +--RLRTHITQAMTEARGRMGVAIKHLESGTEI-VVNADEKFPMASTFKLPVLVTLYDRAK +KGQVKWDETVDVGVHDQHLGSGDLYDVPGVKLSLHNVANLMMMVSDNSGADICLTRA-GA +DNVNALMSSLGAGDIHVDRPTQELILKFAADARDQATPKAFVTLLEKMWRGEAVDQASSE +AMLETMKRCRTGAGRIKGLLPSNTTVAHKTGTIG-GVVDDVGIIYLPEEGHVAIAVLSKQ +TRATDVEVERAIAQIARYAYAYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A649UHI5_ACIBA +--ETLVKVKDAEDQLYARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTT------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Apibacter sp. wkB309 TaxID=1679467 RepID=A0A2S8A6K7_9FLAO +-qSLEKKIHSITKNKKATVGVAVI-FDGKDTL-TVNNDMEYPAMSVFKFHQALALLDYMN +KNLLSLESNIYLKKSDIKKYSPLAKEHPEGNIPIGDLLNYTVSKSDNNASDALYYYMNGT +KMTDLYLRTLGSKNFSIQATEEEMSKDFNNQYINWTTPLEAARLLDIFINKDIFCKNYKD +FLFQAMTESETGSDKLKALLPKKVLIGHKSGSSSRNADNDIGFVYLPNGKQYSIAVFIKD +SKEDDKTNARMIADISQVVYNFy +>[subseq from] Serine hydrolase n=1 Tax=Aphanothece hegewaldii CCALA 016 TaxID=2107694 RepID=A0A2T1LSQ1_9CHRO +---LKQKIEKIAAKYKLQLGTFVVDLDNGAYV-NLSGDSIFAAASTIKIPILVAFLQDVD +AKKIYLDESLVMDKNVIATGSGNMQYKPDQKFTALETATKMITISDNTATNMIIRRLGGK +EVLNQRFLEWGLQQTVINNILPDLEGT------NTTSSKDLVYILNRVNQGDLLSIKMRD +RLIEIMQGTMT-KTLLPAGLEKSAMIAHKTGDIGT-TLGDAGIIDMPNGKRYLMSIMVKR +PHND-ENGRKLIQEVSRVVYQH- +>[subseq from] Beta-lactamase n=1 Tax=Alkaliphilus oremlandii (strain OhILAs) TaxID=350688 RepID=A8MEZ1_ALKOO +---LENKIKGFLRDIDGNVAVVIKNFNNGEII-QINQDYIFPSASTIKLVIMSELLKQVK +ENKLSINETIVITDKMITGGDGILKENVGHRFTLGEIMTLMIIISDNTATNLLIDIV-GM +DNVNRMAQELGLKRTKLQRKMMDSVAV-KYGRENYTSAQDMLNILELTYKGENIDGYYSK +MMLDILKRQQV-GGRLNLYLPENTVIAHKTGDLDR-LEHDVGIVYLPNCE-YIICVLTNE +TK-SNKDGRQIIGNISKLVYDQy +>[subseq from] Uncharacterized protein n=1 Tax=Barnesiella intestinihominis YIT 11860 TaxID=742726 RepID=K0X250_9BACT +--TVGQKIRQAIQGKNATVGVAFSI--DGQLF-TFNDEHRYPLMSVFKLHVAIAALQKME +NECIALDSLRFIESSQIHKYSPLRELYPERNLSYADLMRYAVSQSDNNACDILIDYLGGI +DIVKDRIDKLGITNYNLTETEETMHSRISNCYNNWSTPSSTLQLLEKLYNEPILNETHTE +FLKNILIETSTGKDKIKAGLPDNIVLGHKTGSSDKIGDNDTGVIYLPNGKLCFLAIFIKD +SRESDQTNAQIIADIARIIYN-- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2E7NGH4_9BACT +--RLRGALLAIAQRFPGDVGVYVHHIESGMET-GIDEDTPYGMASTYKVPILVELMTRVE +AGDLSLDDRVAVEAEDQHIGSGLLSTLWAPGMSLRNIATFMIILSDNSATDMLIDRL-GA +DQITAQMRSLGFQNIRVDRTTLELILDFYGGDKDKASARDMTELLVMISEGTAVSRGSSE +VIMEILARTQTGANRLRGLLPPGYSIAHKTGTIGR-IVNDVGVITMPGDGRFAISVFTLA +NEADTELGEHTIAEIARTAYDFf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2E9CSR3_9SPHN +-----SVVRNLGQSFRGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD +RGKLRLADTTTITRNDLTLHQPTAA-MVGTNTSYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPAAIVQALARLKQGDMLSSASSR +LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTVSIPERWALMQAVAKAVAA-- +>[subseq from] serine hydrolase n=1 Tax=Alkaliphilus oremlandii TaxID=461876 RepID=UPI00059FD1CC +---LENKIKGFLRDIDGNVAVVIKNFNNGEII-QINQDYIFPSASTIKLVIMSELLKQVK +ENKLSINETIVITDKMITGGDGILKENVGHRFTLGEIMTLMIIISDNTATNLLIDIV-GM +DNVNRMAQELGLKRTKLQRKMMDSVAV-KYGRENYTSAQDMLNILELTYKGENIDGYYSK +MMLDILKRQQV-GGRLNLYLPENTVIAHKTGDLDR-LEHDVGIVYLPNCE-YIICVLTNE +TK-SNKDGRQIIGNISKLVYDQy +>[subseq from] Beta-lactamase n=1 Tax=Nostoc azollae (strain 0708) TaxID=551115 RepID=D7DW46_NOSA0 +-----TTVQNLARPYNLIPGVFMVDLDTGAYV-DINSNASFPAASTIKIPILITFFQDVD +AGKIRLDEMLTLQKEMISEGSGSLRQAVGSQYTALDIATKMITISDNTATNMLVTRLGGQ +EVLNERFRSWGLATTMIRNPLPDLQGT------NTISPRELGDLIAKVNQGNLVSMRSRD +LMLDIMRRTER-DNLLPSGLGQGARAYHKTGDIGS-MLGDAGLIDIPTGKRYIAAVMVQR +PNND-PSAEKLISSISSAAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides intestinalis TaxID=329854 RepID=A0A412YFL9_9BACE +-qKIEQQIDSFLKDKKATVGVAVLA--NDEIVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KDHIGLDSLIEVKSSQLKPYSPLRDEFPDQDISLGELLKYTISKSDNNTCDILIEYVGGI +DQVNEYVKSLGIKDCNLAATETLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFATQYKD +FLQATMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQETDADNAAIIASISKIVYDT- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. URHD0057 TaxID=1380389 RepID=UPI00048B382C +---IRDRVEELGRAFDGRVGIAVRAVDDNWAT-GWKADEFYPQQSVSKLWVSITAMDAVD +QGRVRLDDKVTLTRSDLTVHQPIRSLILEGGTTLADLMVKAITTSDNTANDKLMRSVGGP +TAVREMIHGKHLGAIRFYDGERALQSRYVDDPYDGAAPSAIAAALARLKRNELLSPASTA +RLLDIMSHTKTGANRLKGGLQPGWVLNHKTGTGQQAGYNDIGILTAPDGRSYSVAVMIKL +TKVPLPTRMALMNNVVRAVIAQ- +>[subseq from] Serine hydrolase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A537M8T2_9PROT +---LEAQVKALGQSFRGDIGIAVQEVDSGWST-AYDGNTFFPQQSVSKFWVALTALDKAD +RGELSLFAPVTMHKEDITLHQPIAAEIGPNGTSVAELMTRALQQSDNTCNDFVLWRAGGP +DAVRNFLRSKGISGIRFGPGERKLQSNYIANPMDGATPLGIVDALARLKRGELLSPASTE +RLLGIMSHTKTGPQRLKGGLQPGWTLSHKTGTGQQAGYNDIGVVTSPDGRSYAMAVMIRR +TSAPLQERMAAMQATVRSVI--- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas pruni TaxID=40683 RepID=UPI000831797E +----TALVPSLTRDFGGKVGIAVTSIDDGWTV-ASNGDLKLPQQSVSKLWVAMTVLDLRD +QGKLSLDDPYTVRKEDLTLHQPIAALVKGDGTTVGGLLQRALTQSDNTANDCLLRLAGGP +TVVRAFLAKKGIADIRFGPGERLLQSRYIADPPDGAAPRAIATALARLKKGELLSPVSTQ +YLMSTMESSHTGRQRLRGAVPEGWTFGHKTGTGQTAGYNDVGFLIAPNGKAYAIAVMIGD +TPKTIPQRQQLMQAVVTGVV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. ba1 TaxID=1522072 RepID=A0A087NE09_9SPHN +--RLIAQFQRFATLTDGTVGITVRDLASGESL-SLNGDTLFPMASAYKVAVAGKIFAMID +AGQLALTDIVPR---------DVATMGPGAALPVAQLLDLMLTQSDNHATDMLVARAGGP +TAVNGWVAGLGIKGLRVDSNTADLLYAFARDPRDSATPTAMTDLVAAIRTGRALSPASTH +AFITIMERCRTGKTRLPGMLPPGTTIAHKTGTIN-GTGNDTGVITLPDGRMFAITVFVMQ +DHRGRVMRDRIMAEAARAAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. SCG-1 TaxID=2072936 RepID=A0A2L0AFC7_9SPHN +-----SIIRSLGQNFNGKVGIAVRRVDADWTV-AWNGTDLFPQQSVSKLWVTMAMLDAVD +RGKLRLSDSVTIRREDLTLNQPLAAMVDSDGTTIEDLMTRAMAQSDNTANDMLLRKVGGP +EAVRSFLARRFVSNIRFGPGERILQSAYLANPPDGAAPSSVVMALAKLKRGEMLSPSSTS +LLLDVMHRAKTGPQRIKGGVPPGWSYLHKTGTGQATGFNDIGIMTAPDGTSYAVAVFIGS +TTVSIPERWQLMQSVARAIAA-- +>[subseq from] serine hydrolase n=1 Tax=Alphaproteobacteria TaxID=28211 RepID=UPI00082A2737 +--TFEQRIAELANPALGRIGVAAVDLATGEEV-MVLGDQLFPMASTSKVAIAATYMEMVE +QGRYTLTSEFPLMMPVASAKFSSAKAPVRAGMPAIDLIEIMITRSSNPATDALLAAVGGP +QAVNAFMARKGIAPFSINRDIATLVRATHIDSRDAATPRAMTRLLAGLYRGEYLSDQSRQ +VILGAMSRTVTGKRRIPANIPLEARVSHKTGSLSN-TSSDIGLIECPDGRVIAVAIYVTG +QGG-KAAREERIAAIARALYDGf +>[subseq from] Serine hydrolase n=1 Tax=Cuspidothrix issatschenkoi CHARLIE-1 TaxID=2052836 RepID=A0A2S6CZ58_9CYAN +-----NSLQTLSSNSTLTAGIFLLDLDNGSYV-DINGNTSFAAASTIKIPILIAFFEDVD +AGKIRLDEKLTLEKEMIAGGSGNVQYPPGTKYTAIDMATKMITISDNTATNMIIAKLGGR +ESVNARFRSWGLTTTMIRNSLPDLEGT------NTTSPKELANLILMVNQGNVVSMRSRD +LILNIMGRTQR-DNLLPAGLGKGANAYHKTGDIGT-MLGDVGLVDVPTGKRYIAAIMVQR +PNND-PLAEKLINSISSTAYQHf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Bhargavaea cecembensis DSE10 TaxID=1235279 RepID=M7NHI5_9BACL +--KLQDKIEKLLKETDATFGISIRHLQSGEEV-RIRADESFQMASVFKVPILLALFEQVH +EGRIDLTTRIALTEEERVPGSGILQELDPGLVTVKDLATLMTIVSDNMAADVLLGML-GK +DAVRDTARRLGAGSISIAHSCWELLSMRKDRENNLCTPDDMTAILTNLAEGAFISPGLSE +SVLDILYRQQL-NDRIPARLPAGTKVAHKTGTIAS-AVNDAGIIDLPGGGPLIISIFSAG +NP-TTDSGEAIIARIAETAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas edaphi TaxID=2315689 RepID=A0A418Q229_9SPHN +------------------------------------------------------------ +--------------------------------SARSLMEAMMIHSSNQATDMLLRNLGGP +SMVQAWLTQQGVTGLRIDRNIAQLLAARRWDIRDSSTPRAMVQLLRRLDSGEMLRPQSKA +YLLDLMARCATGKNRIRGLLPSNVRVQHKTGTLNN-YTSDVGFLTLPDGRRLAVAMFARQ +GV----DRPGTIARAARAIVDGf +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. LPB0140 TaxID=1913578 RepID=A0A1L3J9U4_9SPHN +-qNLQQEIFDLWRVFPGKTGISVHSLDEGWTV-GQRLDDLFPQQSVSKLWVAMTILDQVD +RGKLRLDDEVVITRNDLAVYQPVRDKVLREGESVASLLERAITQSDNTANDSLLRTAGGP +EAVHDFIAKHQLGAIRFGPGERLLQSNYLADPIDGASPRAISLALAKLSRGKLLSYGSSS +YLLDLLNRVRSGPNRLKGGVPSGWSIGHKTGTGQSTGYNDVGILVAPDGRQYMVAVMLGD +TTASIPERMQLMQSVVRAIVR-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium algorifonticola TaxID=2008318 RepID=A0A437JA66_9SPHN +---LLSIIQSLGRGFNGQVGIAVRRVDADWTV-AWNGTALFPQQSVSKLWVAMTLLDAVD +RGKLSLSDSVTVRRDDMTLHQPLASLIGRDGTTLSSLMNRAMTQSDNTANDVVLRKVGGP +EAVRSFLARRFVGNVRFGPGERLLQSTYLANPPDGAAPSAVVMALAKLKRGEMLSPASTQ +LLLATMAQAKTGPQRIKGGVPAGWTYMHKTGTGQSTGYNDIGIMTAPDGTSYAVAVFIGS +TTEPIPKRWELMQSVARAVAEN- +>[subseq from] Beta-lactamase n=1 Tax=Halothece sp. (strain PCC 7418) TaxID=65093 RepID=K9YFE9_HALP7 +--ALKETFKRLAREKQLKPGAFIVDLESGQYV-SLQGESQFSAASMIKVPVLIAFFKAWD +EGRLELDEPLTMTEEVKAGGSGNMQEAVGKQYRALETAAKMISISDNTATNMLIQRLGGK +ETLNELFAAWGLEKTRIRNPLPDLDGT------NTTSPKELVKLLARLNNGELVSARSRD +YILQIMRTTRT-RTLLPQGLDKNATIAHKTGDIGS-LVGDVGIIDRPSGKRYLAAIMVER +PHND-RNANELIRRYSRAAYQYf +>[subseq from] Class A beta-lactamase n=3 Tax=Candidatus Gastranaerophilales TaxID=1906119 RepID=A0A292SSD7_9BACT +---------------NVNVGIATL--KDKDLV--VVNNKKYPLLSVFKYFVAIKVLKYID +QKHISLDTKITINQNDMQTHSPMIKDYKNYPITLAQLLEYMISQSDNNACDILIDYSGGI +NELEKFIHELGFNDIIIKVNEKDMNSDIYNQYLNTSTPKDIVLMMKRVKDNNILSSSSFA +FLENIMLKTSTGENKIKAGLPKNIKIYHKTGSGSRTADNDAGYVRLPNGDLYYIAIMIKD +SPLSDDENSKIISDISKIVYQYf +>[subseq from] class A beta-lactamase n=1 Tax=Bryobacter aggregatus TaxID=360054 RepID=UPI000563C606 +--TLQTKLDGLGKSIDGRVGICVRDADTTTCV---RGAERFSLQSVMKLVVGIAVLDAVD +HRGWKLEDPVLVRKQDLSLVQPISKLVGESGTTVGDLVRRAIVDSDSAAVDILIAKLGGI +EKVQAFLNRKKIAQVRLDRDERHLQTKYQKDPRDTATPLGMTQLLQDLALGKLVSKSSTA +FLMRVMEETVTFPDRLKAGLAPGWKLGHKTGSSSTVATNDVGVMTAPDGRQISVVVFVAD +SRATLKEKAVVMSGVSRAVCESy +>[subseq from] Beta-lactamase n=1 Tax=Microcoleus vaginatus FGP-2 TaxID=756067 RepID=F5UBJ4_9CYAN +---LKTQVQVLATENSLTAGIFLVDLDTGSYL-NFNGDTAVASASTIKVPILVAFFQAVD +EGKVQLDQMLTLKSEHIVGGSGEMQDAPGKKYSALEVAQNMIVVSDNTATNMMIELLGGA +EVLNQHFANWGLSTTVLRNNLPDLEGT------NTTSPKDLINIIAQVDRGNLVSVKSRD +RILQIMRQTQN-ASLLPKGLGEGSVIAHKTGNIDT-MLADAGMVDLPNGKRYLVAVMVKH +SPETEKPAQTLIREISRISYRY- +>[subseq from] Putative beta-lactamase n=1 Tax=Alistipes putredinis DSM 17216 TaxID=445970 RepID=B0MWK8_9BACT +--DLSYRLKKVIKDKKAEIGIAVI-LDAQDTV-TVNNDDRYPLMSVFKFHQALAVADYLD +RNGLTPDTEIFIPEEELVPYSPLRKEFPEGELSVSRLLEYSLQLSDNNACDILFEHTGGP +AATDRYVRSLGLRNFAIAATEQQMHDDPQTCYENWSTPLEAAALLELLVTEQILTPTLRE +MIRQNLINCKTGADRLPKPLSTGAVIGHKTGTSDRDGTNDPGFVILPDGTRYTIAVFIKD +SAENPETNARIIADISETVYRY- +>[subseq from] Serine hydrolase n=1 Tax=Microcystis viridis Mv_BB_P_19951000_S68D TaxID=2486270 RepID=A0A552HNP4_MICVR +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] serine hydrolase n=1 Tax=Scytonema sp. UIC 10036 TaxID=2304196 RepID=UPI0012DAD078 +---LKSAIQSLAASNNLTPGVFLLDLDNSGYV-DLNGSASFAAASTIKIPILVAFFQDVD +AQKIRLDESLTMSKGMVAGGSGNMQKPVGTQFTALEVATKMMTISDNTATNMLIARLGGI +DALNQRFQSWGLTTTAIRNILPDLGGT------NTTSPKELGTLMAMVGKGNLVSMRSRD +RILDIMRRTVR-NHLLPAGLGPGATIAHKTGNIGT-ILGDAGLVDVPTGKRYVVAVMVQR +PRND-TDAEKLIVSISRVAYQQ- +>[subseq from] serine hydrolase n=1 Tax=Cyanobacterium aponinum TaxID=379064 RepID=UPI0012BB1710 +---LRGKFDTLRAKYQLEPGAFFVDLDNGAYV-NYNGIAPFPAASTIKIPVLVAFLQDID +EGKIYLDEKLTMTEANRVPHSGNMQYQPGTQFTALYTATEMIINSDNTATEMIIERLGGK +DELNKRFQEWGLENTVIRNLLPDLEGT------NTTSPRDLGILLAKVNQGDLLSVRSRD +RLLEIMRRTKT-QTLLPQGLENNAIIAHKTGDIGT-VLGDAGIIDMPTGKRYIGAVLVKR +PHND-YSARTLIQEISRTAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. URHD0007 TaxID=1298856 RepID=A0A2U1FZ26_9SPHN +------------------------------------------------------------ +--------------------------------SARSLMARMLIHSDNRATDMLIRDLGGP +SAIHNWLRQNGVTGLRVDRNIAGLLAAKRWDSRDSSTPTAMVDFLRRIYRAELIKPESRN +YLLDLMAQCETGKNRMKSLLPNGTPVEHKTGTLT-GLTDDVGFITMPDGHRIAVAIFARG +GS----NRPRTIAEAARVIYDGf +>[subseq from] Serine hydrolase n=3 Tax=unclassified Sphingomonas TaxID=196159 RepID=A0A0Q4F9Y0_9SPHN +---LVSAINALGGGFQGKVSIAVRSIDDGWVV-GHAMDQRMPQQSVSKLWVALTTMNAID +EGKLALTTPVTITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTMSDNTANDKLLNLAGGP +VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLHHGMLLTPQSTQ +WLLDTMSHTRTGRARIRAALPAGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD +TSRPVQERQQLIQTVVSSIV--- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. YH-07 TaxID=2182384 RepID=A0A345YI45_9SPHN +-qELDREISRIGGTFAGHVGIAVHDIEALRTL-HFNGLERFPQQSVSKLWVAMTALDEVD +AGRLDLAEMVEIRSRDLTVYQPIRKIVRRKGSDYADLIARAIVESDNTANDRVLRRVGGP +EAVQDFLDGHGLSSIRFGTDERTKQSTYLADPPDGAPPVAIVEALARLYRGDLLSEESTR +LLLDTLEQTKSGPRRLKAGAPEGWTVRHKTGTGQQSGYNDVGIVTSPQGRGYAVAVMIAR +TREPTLTRMEMMQSIVQAIAKY- +>[subseq from] Uncharacterized protein n=1 Tax=Propionispora sp. 2/2-37 TaxID=1677858 RepID=A0A0K8JD24_9FIRM +-eALRKKIEQMTAPYTGNWGILVKNINTGESL-SIEPDRVFPSASMIKLPIMFEVMRQAA +AGALSLDDTLLVTAAARVGGAGILHERPGIAMTIRELVTLMIIISDNTATNLLIDLV-GM +EAVNRTSTNLGLCSTFLRRHMMDFAAA-KAGNENETTAADMALMLEAVYQGRGLPQGYAD +IMLGILKRQQV-RDKLPFYLPEEFEIANKTGTLH-GVEHDAGILYFPDG-PYIVCVLTGN +LTAN-YEGIQLAAGIGKAIYEH- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium baderi TaxID=1332080 RepID=A0A0S3EX37_9SPHN +--RLLAQFQSFAVLTDGTVGIAVQDLSTGEEQ-SLNGDTLFPMASTYKVAVAGKILSMVD +AGTLNLQDLLD-------------PPLPAKSRSVHDLIDLMLTHSDNDATDALVARAGGP +AAIDEWVGALGVKGLRVDSDTAHLLYAFTRDPRDTSTPRAMNALLANIQLGKALKPASTA +YLLDMMERCHTGKARLKAMLPPGTRIAHKTGSLN-GYGGDVGIVTLPDGRMFTISVFVMK +DYKGRETRDSIMAHAARAAYDYf +>[subseq from] Serine hydrolase n=3 Tax=Microcoleaceae TaxID=1892252 RepID=A0A3D5GCE9_9CYAN +--ALKTQIQVLATENNLTPGIFLVDLDTGSYL-NLNGDATFASASTIKLPILVAFFQAVD +EGKVHLDQMLTLGAEHIVGGSGEMQDSPGRKYSALEVARKMIVVSDNTATNMMIELLGGA +EVLNQHFATWGLSATVLRNKLPDLEGT------NTTSPKDLINVMAQVDRGNLVSVKSRD +RILQIMRQTQN-DTLLPKGLGEGATIAHKTGNINT-MLADAGMVDLPNNKRYVVAVMVKH +SPETEKAAGSLIRDISRMSYRY- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9UW30_9BACT +-qKLESTIRDVDSHLDGVMGVAIEDLTTGDHF-FLHENEVFAQASSIKITVLAQLYQQAQ +QGKLKLTDLYTVQASDLVPDSDIMGGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GM +DNVNSMLDSLGLSHTRLRRKMMDLKAA-AEGRENISTPSEMMTLLEAIHHGKVLNKESTA +DFFKVLSTNKS--SWIPRDLPADLKIANKPGSLE-AVRNDSGIVFVEGH-PYVICVMTSF +LR-NERDGEDAISKISLAAWRMf +>[subseq from] Putative beta-lactamase n=1 Tax=Planktothrix sp. PCC 11201 TaxID=1729650 RepID=A0A1T4ZDZ9_9CYAN +---LKTAILGLAKDSKLKPGVFLVDLDTGKYV-DIQGQEALPAASTIKVPILVSFFQAVD +EGRLRLDEVLTMEAKHVAKGSGELQKPVGSKFTALETANLMITNSDNTATNMLIDRLGGI +ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINQGKLVSLKSRD +FMLRIMQQTRN-RSLLPSGLGEGAFIAHKTGNIDS-VSGDIGLIDMPNGKRYLVGVLVER +EA-DDPQANELIRQISSTIYQYf +>[subseq from] Beta-lactamase n=1 Tax=Richelia intracellularis HH01 TaxID=1165094 RepID=M1WZ40_9NOST +----------LANNTKLTPGIFLVDLDNGNYV-DFNAANSFPAASTIKMHILVAFFQDID +NGKIRLYEQLTMEKGLIVGGSGNMGQKPGTKFTALEVATRMMTTSDNTATNMLIKRMGGI +DVLNQRFRSWGLSITTINNLLPDLKGT------NITSPKELGELMAMVSKGNLVTMRSRD +RIMDIMRRNTR-NNLLPAGLPKGATIAHKTGDIGS-MLADAGLIDLPTGKRYLAVVMVQR +PYND-PSAETLIKSVSRIACQQf +>[subseq from] serine hydrolase n=1 Tax=Porphyrobacter donghaensis TaxID=267135 RepID=UPI000A3D187E +---FEQRIRELANPAEGRIGVAAIDLATGEEI-MVLGDQLFPMASTSKVAVAATYMSMVE +QGRFSLTSEFPLMLPVRSASSPKAPVRAGQTMQAIDLIEIMITRSSNPATDALLAAVGGP +DVVNNWVRRQGIGEFSINRDIATLVRVTHIDSRDAATPRAMVRLLAGLYRGEFLSDESRR +VILGAMSRTVTGKNRIPAYIPLEARVSHKTGSLFN-TSSDIGLIECPDGRVIAVAIYVTG +QG-TKLARQDRIAAIARALYDGf +>[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium UBA11162 TaxID=2055781 RepID=A0A355DVM7_9CYAN +---LKSQIQALTAQNKLQPGIFLVDLDTGTYV-DWQGQSILPAASTIKVPILVAFFQDVD +AGKIRLDEPLTLEPDVIGTGSGELQQKLGHQYTALEVVTKMSAISDNTATNMIIKRLGGA +AVLNQRFRSWGLTATVINNPLPDLEGT------NTTTARDLGNLMGMVNQGQLLSLRSRD +RLLNIMQQTVN-NSLLPKGLGSGATIAHKTGDIGS-LVGDVGLVDMPNGKRYIIVTMVKR +PHND-ASASELIRNISRTVYNYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V578_9BACT +------------------------------------------------VMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPASWTV---------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Calothrix sp. NIES-2098 TaxID=1954171 RepID=A0A1Z4FTT0_9CYAN +-kALEPQIKALMNRYSLQTGMFFLDLDTGNYL-DIGGDRVFPAASTIKLPILIAFFQDLD +AGKVRLDETLTMRGDLVTNGSGVMQERVGKKYSALETITKMVTISDNTATNMIIDRLGGA +AKLNQRFRSWGLKDTVIRRLLADLRGT------NTTSSQDMARVLALLVNNKLVSESSKE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKRYLAAIFVKR +PYKD-SRGRDFIRQVSQLVYNY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf339 TaxID=1736343 RepID=A0A0Q6KCY5_9SPHN +--ALQASIETLARNFDGRAGIAVRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITVLDQRD +QGKVRLDQPITVLPTDLTLHQPIAYLVAKTGTTVGGLLTRALTQSDNTANDRLLTLVGGP +EAVRRMIAAKRLGDIRFGPGERMLQARYVADPPDGAAPLAIADAISRVARGELLSETSTR +ILLDTMGASITGRARLRAAIPAGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYALAVMIGD +TRRPIRERQMLIQNVAATVAS-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dysgonomonas sp. HDW5A TaxID=2714926 RepID=UPI00140A6885 +-nTLRQEIQDIIQNKKATVGVAII-FDGKDTL-TVNNQYRYPTMSVYKFHQALAVLDYLD +KYNLPLEQQVYVSKSALHPYSPLRDKKPEGNMPIKELMQYSVSQSDNNTCDILFNFLGGT +TPVEQYIKGLGIQQIAITKTEKEMSEDFDNQYGNWTTPYAAVQLLEIFLQQELFASHYKN +FLLDALIQTSTGKDKIKSLLPARTVVGHKTGMSSKAGDNDLGFIKLPNDKNLSIAVFIVN +SIENDTTNAEIIAQISKVTYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingosinicella vermicomposti TaxID=614671 RepID=UPI000D0FDF4B +-rALSQRINALGSSFNGDIGIAVKDIQTGFTT-AYDGSTFFPQQSVSKFWVALTALDRAD +RGLLSLEAPVTVTRSDLTLHQPIAAQVGANGTTINSLMYRAITQSDNTCNDFVLWKAGGP +DAVRSFLANKGIGGIRFGPGERKLQSNYIRDPMDGATPLGTVDALARLKKGELLSPYYTQ +KLLDIMSNTRTGAQRLKGGLAPGWKLAHKTGTGQQAGYNDIGIVTGPDGRSYAVAVFIRR +TSAPLGHRMSTMQNVVRAVVDY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A059ULV6_ECOLX +------------------------------------------------VLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKV------------------------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa Ma_QC_C_20070703_M131 TaxID=2486263 RepID=A0A551X6L3_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDESLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSANIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] class A beta-lactamase n=1 Tax=Undibacterium sp. KW1 TaxID=2058624 RepID=UPI001331E55A +----QNVIESIAMDSGGRLGASLLVLETGQSL-WILPDTAAPMQGVSKLPIVMAALAAVD +KNKLKLDQKVTINKEDLIPPSALRDEHPEGNITAKELMHHAIVDNDGTASDALLRLLGGP +PAVMQYLAQLDIKDIKVLDTEKDLAKSWNMQYRNTATPKAMIKLLQTVQEGKALSPKSRE +LLLKWMTDTEVNAARIKALLPAGTAVVHKAGSSPTAAHNDVGIVTLPNGHHMAVAVFLTD +SKAPHASRDLTIAKITRVGWDAw +>[subseq from] Uncharacterized protein n=3 Tax=Luteibacter rhizovicinus TaxID=242606 RepID=A0A1L3ESC0_9GAMM +--RLQASLDRIASEAPGTLGIVVMDPSTGKSI-KVNDGRSYLMMSAFKAPIAAAVLARVD +SGELKLDQKVHLVPADIVPGSPSLGKRLEAGVSVEEVLRAAVTQSDNTAVDALLRLLGGG +HAATAFLESKGVHGMRIDMGERELSLAVLASKVDSTTLDAAATFLDKLQSGALVSSSSTN +MLLGMMTAQVI-PNRVRAGLPVGFQLADKTGTAGLGAWNDMGIVTAPNGRRMVVAVFLSD +SPAKPKQADAWFAEIGKAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum sp. B39 TaxID=95609 RepID=UPI0005538D04 +------------------------------------------------------------ +-----------------------------------QLCEAAITLSDNTAANLLLESMDGP +AGMTRFVRSLGDELTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ +QLAQWLVANQTGDKRVRAGLPKGWKVGDKTGTGRLGTANDVGVVWTEKGAPLLFAVYLTE +NAATDARRD-------------- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A380E9A1_STAAU +---------------------------------------------------------QVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas turrisvirgatae TaxID=1888892 RepID=A0A1E3LV03_9SPHN +--TLSSTVTSLARDFGGVVGISVRSIDWGWQI-DANGNRRMPQQSVSKLWVAMTVLDARD +KGRLTLDDPVTLTRENLTLHQPIAALVVKDGTTVRELLLRAMQQSDNTANDRLLTLVGGP +EAVRAFIRERQLGQIRFGPGERLLQAAYVADPVDGAAPSAIALALARLKAGELLSPSSTH +FLTTVMSGTRTGRARLKAAVPPGWSLAHKTGTGQTAGFNDIGILTAPDGKSYTLAVMIGD +TARVPRDRQLLMQAVVTAIVA-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520FLL5_SPHSX +------------------------------------------------------------ +---------------------------------AAKVMELMIIHSDNQATDNLLAALGGP +VAIQQWLWSQKITGIRMDRTIAQLLRGHLADSKDVTTPVAMVTLLNKLDNGSVLTAQSRT +FLLELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG +GR----DRQPVIAEVARVIYDRf +>[subseq from] serine hydrolase n=1 Tax=Bhargavaea sp. CC-171006 TaxID=2302363 RepID=UPI0012FB85E1 +--RLQKKIEKLLNETDATFGISIKHLQSGEEV-RIHADEPFQMASVFKVPILLALFEQVH +EGRIDLTTRIALTEEERVPGSGILQELDPGLLTIKDLATLMTIVSDNMATDVLLGML-GK +NAVQDTVRKLGAENMMIVHSCWELLSMRTDRANNLCTPDDMTAILSKLAEGAFISPAVSD +TVLDILYRQQL-NDRLPARLPAGTKVAHKTGTIAS-AVNDSGIIDLPGGARLIISIFSSG +NP-TTESGETVIARIAETAYQYf +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059XD23_9BACT +-eKLAERLRSMIEAAGGDVGLTVIHVESGRTV-SIHGDIQLPLYSVFKLPLAVAVLKDVE +EKRLQLDHKVVTSPTEIVPGSQENTDLWRKPRTVAELLELSISRSDNTSADKLLKLVGGP +EAVTNRMRSLGFPNFMIHSSVSEYVKD--RSKVNTGTASELGRLLVELQQGHVLQKPQLS +VLLGFMERATTGNHRLRGLLPAGTLVADKTGTGEAGATNDVGLITLPNGGHLAIAVLIKA +SKLAPTEQEKLIAELARVSYEA- +>[subseq from] Serine hydrolase n=1 Tax=Microcystis sp. M_OC_Ca_00000000_C217Col TaxID=2486213 RepID=A0A552AB86_9CHRO +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMEYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Microcystis flos-aquae DF17 TaxID=2060470 RepID=A0A3E0KV31_9CHRO +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDEPLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSANIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] serine hydrolase n=1 Tax=Aliterella atlantica TaxID=1827278 RepID=UPI0005D39EA4 +---LKAAVQQLSTKNGLTPGIFFVDLDTNNYL-DWNGSLTFAAASTIKFPVLVAFFQDVD +AGKIRLDEKLTLKKELIGGGSGDMQYRPGTKFTALTTAAKMIIISDNTATNMLIARMGGI +AALNDRFKNWGLGSTIIRNQLPDLPGT------NITSPKDLAHLMQLVDKGELMSLRSRD +RLLDIMRQTKT-RTLLPRGLGEGSTIAHKTGDIGS-MVGDVGLIDMPNGKRYVGVAMVKR +PHND-SRAQELIRQISRSVYQHf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides intestinalis CAG:315 TaxID=1263048 RepID=R7DLU5_9BACE +-qKIEQQIDSFLKDKKATVGVAVLA--NDEIVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KDHIGLDSLIEVKSSQLKPYSPLRDEFPDQDISLGELLKYTISKSDNNTCDILIEYVGGI +DQVNEYVKSLGIKDCNLAATETLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFATQYKD +FLQATMQETSTGKDKLKGQLPADVIVGHKTGSSNRTADNDAGFVILPNGQKYYIAVFVME +SQETDADNAAIIASISKIVYDT- +>[subseq from] Beta-lactamase class A n=1 Tax=Altererythrobacter xiamenensis TaxID=1316679 RepID=A0A1Y6FIF9_9SPHN +--TFEQELEELGAGLPGEVGIAVVDAKTGYSY-DFDGEEILPQQSVSKLWVTMAALDAVD +RGTLDLSERVTVRREDLTVYQPIRDLVRARGTDYGDLMRRAITRSDNTANDLLLRRVGGP +EKVQAYLDARGIENVRFGTDERTKQSRYLADPIDGASPLGIARALAMLSRGELLSPGSTA +FLLDLLSQTKSGPNRLKGGVPPDWSFGHKTGTGQQSGYNDIGLLTAPDGRTYAMAVMIGR +TRVPTPERMEMMQEVVRATV--- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. TZW2008 TaxID=1917973 RepID=UPI001181ADDC +--QLTASIQQLVREFPGTAGVAIRAVDEGWTV-QANGRLKLPQQSVSKLWVAMTVLDQRD +QGRLRLDDPISVTPADLTLHQPIAYLVKGGSTTVGNLLFRALTQSDNTANDRLLTLVGGP +SAVRDFIERKQLGDIRFGPGERLLQARYIVNPPDGAAPLAIADALARLFRGELLSETSTR +LIVSTMESSRTGRARLKAGIAPGWTLAHKTGTGQNAGFNDVGVITSPDGRRYAVAVMIGD +TTQPMRVRQQLIQAVAATVT--- +>[subseq from] serine hydrolase n=1 Tax=Richelia intracellularis TaxID=1164990 RepID=UPI0012DF4380 +----------LANNTKLTPGIFLVDLDNGNYV-DFNAANSFPAASTIKMHILVAFFQDID +NGKIRLYEQLTMEKGLIVGGSGNMGQKPGTKFTALEVATRMMTTSDNTATNMLIKRMGGI +DVLNQRFRSWGLSITTINNLLPDLKGT------NITSPKELGELMAMVSKGNLVTMRSRD +RIMDIMRRNTR-NNLLPAGLPKGATIAHKTGDIGS-MLADAGLIDLPTGKRYLAVVMVQR +PYND-PSAETLIKSVSRIACQQf +>[subseq from] Putative beta-lactamase protein n=1 Tax=Microcystis aeruginosa PCC 9443 TaxID=1160281 RepID=I4GBM6_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSANIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Beta-lactamase n=1 Tax=bacterium TaxID=1869227 RepID=A0A3N9MWA4_9BACT +---LADEIKRIIKLCKSTVGVGIVHIESGLSW-YNNREVSFPMASTYKIPIAMKLLKDVE +SGVLVMEDMISIKQYDQHPGSGILSELIDNPLSIANLFELMMTISDNTATDIILSLVGGG +GAVTDYLKSLEITGMTVDRSTLEMLSEFLNIHKDVTTPEAMSRLLGKIMIEGVLNRTHIE +ILLDAMRKNKYGDDRIKGFLPPHVIVAHKTGTLGT-ITNDAGILTLPNDGHIALVVLIKK +SDDSNAEREATIAHIARATYDYf +>[subseq from] Serine hydrolase n=3 Tax=Sphingomonas TaxID=13687 RepID=A0A0Q6AFY2_9SPHN +--ALVQAINALGGGFQGHVGIAVRSIDDGWVV-GHAMDRRMPQQSVSKLWVAMTTMSAID +EGRLALTTPVAITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTMSDNTANDKLLNLVGGP +VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLHHRMLLSQQSTA +WLLDTMAHTRTGRARIRAALPPGWSVAHKTGTGQTAGFNDIGIITAPDGKAYAIAVMIGD +TARPVPERQQLIQTVVSSIV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Granulicella pectinivorans TaxID=474950 RepID=A0A1I6LTI9_9BACT +-qTLQQKLAKIAASANETVSVACALPNSTLNC-DLNPDGHPPMQSVFKLPLGVAMLHLVE +QGNFTLDQPIRFLPSDRIQYSPLQDKYPDANVPLRELIRLSVYLSDNAAADTLLRLLGGT +AALQKYMDTLGIQGFHIEDTEYSLHTDAQFQFRNWFTPRAAVSFLRLLADNSPLTPEHTQ +LLFSFMQGPGNGTGRIKAGLPADTVVRHKSGTSDY-AMNDIALITLPDGRTLALAVFLTN +STDSQKDREATIAAIAKAVYE-- +>[subseq from] serine hydrolase n=1 Tax=Nostoc sp. B(2019) TaxID=2690446 RepID=UPI0013919CE7 +---LEPQIQALKARYSLKTGMFFLDLDTGNYL-DVGGDRIFPAASTIKLPILIAFFQDLD +AGKVTLNEMLTMRRDLVTNGSGTMQERVGKKYTALETVTKMVTISDNTATNMIIDRLGGA +ARLNQRFRSWGLKDTVIRRLLADLRGT------NTTSSQDMTRALALLVNNKLVSPESRE +QALDILYRTVT-NTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKRYLAAIFVRR +PYKD-TRGRDFIRQVSQLVYNY- +>[subseq from] Putative beta-lactamase n=1 Tax=Planktothrix agardhii CCAP 1459/11A TaxID=282420 RepID=A0A479ZPV6_PLAAG +---LKTAILGLAKDLKLKPGVFLVDLDTGNYV-DIQGQEAVPAASTIKLPILVSFFQAVD +EGRIRLDEVLTMEEKHIAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI +ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINQGKLVSLKSRD +FMLRIMQQTRN-RSLLPRGLGEGAFIAHKTGNIDS-VSGDVGLIDMPNGKRYLVGVLVQR +EA-DDPQANELIRQISSTIYQYf +>[subseq from] serine hydrolase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI0009ECA5F1 +--ALVATINALGGGFQGRVGIAVRSIDEGWVV-GHAMDQRMPQQSVSKLWVALTTMSAID +EGKLALTTPVTITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTLSDNTANDKLLNLAGGP +VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLRHGMLLTPQSTS +WLLDTMSHTRTGRARLRAALPTGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD +TARPVQERQQLIQTVVSAIVA-- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides plebeius TaxID=310297 RepID=A0A414QT22_9BACE +-qELYTNIHQFISQQKAEVGIAIIA-DGKDTV-TVENNRRYPLMSVFKLHQALAVGNYCK +RHQLSFDTLLTVDSTDLQPYSPLRDRYPHGGFSLKQLMEYTLHLSDNNACDILFKFTGGP +AVTDRYIRSLGVNDFSIQYTEDDMHRDLNLGYENWSTPLAAAEVIEALLTRTLFDKPHQE +FIKEALITCQTGTSRIVHPLQKQITVGHKTGTGDRNAINDAGFVQFPNGHRYTLVVFVKD +SQESMEDTEAIIAQISEMVYQAf +>[subseq from] serine hydrolase n=1 Tax=Anabaena sp. PCC 7108 TaxID=163908 RepID=UPI000475627D +----KTSVQNLATASNLTPGVFIVDLDTGAYV-DINSNASFSAASTIKVPILIALFQDVD +AGKIRLDEMLTLQQEMIAGGSGTLKSRVGTQYTTLEIATKMITISDNTATNMLIARLGGK +DVLNERFRTWGLTTTMIRNSLPDLQGT------NTTSPRELGNLIFMINQGNIVSMRSRD +LMLNIMSRTER-DNLLPSGLGQGSRAYHKTGDIAT-MLADAGLIDIPSGKRYIATVMVQR +PTND-PRAEKLISSISAAAYQQf +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium artocarpi TaxID=1414727 RepID=A0A1B9A058_9FLAO +--EFKKIIESIIANKKADIGVSIFISGTKKEVtQINGNNLYPMLSTFKFHIALAILHKVE +KGELSLQQKIFIKKEELLEYSPFKEKYPEGNLTLEEALQWIVIYSDNNLTDILLRLIGGP +QYVEKFINS---KNVIIKNDEEDMHKDWDSQFINKTTPNETIRLLQDFYNGKILNKEHTK +WLYTNMMSTASGAKRLKGKLPQNIKMAHRTGTSFTGAINNFGIIELPNKKNIYIAVFVHD +TYETFNNSEAIIADISKATYDYy +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium GWA2_62_23 TaxID=1797924 RepID=A0A1F9REV9_9BACT +--------GKTSVAYRGRVGIYLKDLHTGKTW-EYNADRLFPSASLIKVPIMAAVFEKIK +LGSITLDTQIKLTRKGRVGGSGSLKWVREGTLSVMEIIYKMITESDNTATKMLIDYV-GM +DYLAMTFARLGLEHTNITPEGMSLTSG-RVKNENFTTAREMAGLMERIYQGELVNRDASE +FMLDVLKHTKS-RSRLRKGLPLGWEIGHKTGLLRK-SCHDVGIVFSPRGD-FVIAVLTSN +VP-DYRSAKNFIARVAKLTYRYy +>[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A537MKH7_9PROT +------------------------------------------------------------ +--------------------------------TARVLMEAMIIHSDNRATDMLIATLGGP +SAIDSWLRAHRLSGIRADRTIATLLSDRRTDVRDSSTPTAMLGLLRAIDSGEALTPQSRA +HLLDLMRRCATGTNRIRGLLPPEARVEHKTGTLN-GYTGDVGYLTYPDGRRIAVVFFARG +GS----NRPGVISTAARAIYDGf +>[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa TA09 TaxID=2060472 RepID=A0A3E0L7S4_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSANIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_59_12 TaxID=1797946 RepID=A0A1F9UG29_9BACT +--SFTAALRQRSVRFQGSVGYVVKDLRSGEIV-AINQDRVFPSASLIKLPILVAAYQAVE +DGRASLSQPITLHRRDRRGGSGILKWAMPGTFTLRELLEYMIIHSDNTAAEMVIQRL-GF +DYLRHTFDRLGLQDTEIHPDGFRLTGR-RVAEDNRTSPRDMAYLLEKIYHGGLVSRDASE +DMLRILKHQKL-RDRLPRFLPTGWQIAHKTGLLRR-ACHDVGIVFSPQGD-YLICVLTSH +QA-TYKNAKRFIASLGRITYDYy +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas turrisvirgatae TaxID=1888892 RepID=UPI0009A1B113 +--TLSSTVTSLARDFGGVVGISVRSIDWGWQI-DANGNRRMPQQSVSKLWVAMTVLDARD +KGRLTLDDPVTLTRENLTLHQPIAALVVKDGTTVRELLLRAMQQSDNTANDRLLTLVGGP +EAVRAFIRERQLGQIRFGPGERLLQAAYVADPVDGAAPSAIALALARLKAGELLSPSSTH +FLTTVMSGTRTGRARLKAAVPPGWSLAHKTGTGQTAGFNDIGILTAPDGKSYTLAVMIGD +TARVPRDRQLLMQAVVTAIVA-- +>[subseq from] Beta-lactamase class A n=2 Tax=Hyella TaxID=945733 RepID=A0A563VKI7_9CYAN +---LQKQLQILTDRYQLEPGILIADIESKDYV-NLGGTDTFAAASTIKIPILVAFFQDVD +AGKINLNQPFTITKESIADGSGYMQYQPGTKFSALKIASSMITVSDNTATNILIEHLGGK +KALNQRFADWGLTTTQISDRLPDKQGT------NTTSPEDLSNLLLKIDRGELVSLASRD +RILAIMKQTER-NTLLPQGLGKDAAIAHKTGTLLS-VLGDTGIIYTPNGKRYIASVLVKR +PDND-PQAESLIQEISRTAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Granulicella sibirica TaxID=2479048 RepID=A0A4Q0T8J2_9BACT +---LKQAIATIAADSDSTVAVACALPNAQLDC-SLNADSHPPMQSVFKLPLAVTVLHFVE +QSKLSLDQQVRFLPADRIPYSPLQDEHPAPNVSLRELFRLAVNLSDNVAADILLRVIGGP +QVVQAYITSLGIKDFHIVDGEHGLYLDAQNQFHNWISPSAAVQLLRLLADASPLTPADTQ +LLFGLMETSPMAPHRIRDGVPPGTVVRHKGGTSQY-ATNDVALITLPDGRTLALAVFLTN +STDDDKTRDATIASIAKAIYE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Myroides marinus TaxID=703342 RepID=A0A1H6SUI0_9FLAO +hqELNNKIKGVISNKNATVGVAIIY-DAKDTL-TVNNDHKYPTMSVYKFFQALNILDYMD +KHNISLDTEIYIKKEDLKEYSPLRDKSPKGEMSLRELIQYTASHSDNNISNLFFRSFIGP +KMTDLYFRSLGIQNFEIVSSEETMSLDFNNQYQNWITPLEATRILEMFRKEELLSPDYNN +FLRQAMIDTKSGQDKVKALLPKNTVVVHKTGMSFRAADNDLAIVYLPNGKQFSIAVFIMN +SKESDKTNASIIAEIAKLAYDYf +>[subseq from] Putative beta-lactamase protein n=1 Tax=Gloeothece citriformis (strain PCC 7424) TaxID=65393 RepID=B7KDD6_GLOC7 +--SLEKKITDLAAKYKLQPGSFFVDLDNGAYI-DVNGQAPFSAASTIKIPVLVAFFEDVD +AGKIYLDEELVMTKDVIGSGSGDMQYPVGKKYSALETAAKMNIISDNTATNMLIKRLGGK +EALNERFKAWGLTQTVINNPLPDLEGT------NTTSPRDLAYLLARVNQGEILSLRSRD +RLMGIMQKTKT-RTLLPQGIEKDAIIAHKTGDIGT-VLGDAGIIDMPTGKRYVGAVLVKR +PHND-YSARTLIQDISRTVYQHf +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium ureilyticum TaxID=373668 RepID=A0A1N7KBQ0_9FLAO +--EFKKIIESIIANKKADIGVSIFISGTKKEVtQINGNNFYPMLSTFKFHTALAILHKVE +KGELSLQQKIFIKKEELLEYSPFKEKYPEGNLTLEEALEWIVIYSDNNLTDILLRLIGGP +QYVEKFINS---KDVIIKNDEEDMHKDWDSQFINKTTPNETIRLLQEFYNGKILNKEHTK +WLYTHMLNIASGAKRLKGKLPQNIKIAHRTGTSFTGAINNFGIIELPNKKKIYIAVFVHD +TYETFENSEAIIADISKATYDYy +>[subseq from] Beta-lactamase class A n=2 Tax=Pedobacter steynii TaxID=430522 RepID=A0A1H0JQV5_9SPHI +--QLQERIKHIIDTAGGKIGVGVKGMDFKGGF-VINNNHGYPMMSVFKFPLAFAILGKVD +KGELQLSQKFHMPKETLDTWSPMVKDFPNQDMTLADLLTYTVSKSDNNACDFLYTKVGGP +AAVNQYLHNAGVKEISIVYTEGEMEKDWALQYKNWCKPAAALQLLQLLYNQKLLSKSSND +FLMQIMRELPDWGKRITVLLPPATELIHKTGASGANAFNDIGIVTLPDGKHLAISVFVSD +FKTPKERGINVIAAISKEIWDYy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=G5CK57_PSEST +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPIDKRDSTLP---------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. ERG5 TaxID=1381597 RepID=UPI000691C90E +-qALVTNIAALGRSFNGRVGIAVRSVDNGWSV-QTNGDALLPQQSVSKLWVAMTVLDFRD +AGKLRLEDPVTLKPEDLTLHQPIAALIKADGTTIGALLQRALTMSDNTANDRLLRYVGGP +KAVRAFIQRKQLGDIRFGPGERLLQSRYVTDPPDGAAPMAIAGALMKLKRGELLSASSTE +YLIGTMQSSKTGKMRLRGAVPEGWSFGHKTGTGQTAGYNDVGLLTAPDGKSYALAVMIGD +TPRPIPDRQALMQAVVAAVV--- +>[subseq from] Beta-lactamase n=2 Tax=Microcystis aeruginosa TaxID=1126 RepID=A0A0A1VYH0_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Microcystis wesenbergii Mw_MB_S_20031200_S109D TaxID=2486241 RepID=A0A552LWF9_9CHRO +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVASKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +EALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A0G3VQK8_ECOLX +---------------------------------------------------CGAVLSRVD +AGQEQLDRRIHYSQNDLFEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLR------------------------------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=marine metagenome TaxID=408172 RepID=A0A381RP82_9ZZZZ +--RLRGALLAIAQRFPGDVGVYVHHIESGMET-GIDEDTPYGMASTYKVPILVELMTRVE +AGDLSLDDRVAVEAEDQHIGSGLLSTLWAPGMSLRNIATFMIILSDNSATDMLIDRL-GA +DQITAQMRSLGFQNIRVDRTTLELILGFYGGDKDKASARDMTELLVMISEGTAVSRGSSE +VIMEILARTQTGANRLRGLLPPGYSIAHKTGTIGR-IVNDVGVITMPGEGRFAISVFTFA +NEADTELGEHTIAEIARTAYDFf +>[subseq from] Putative beta-lactamase protein n=1 Tax=Microcystis aeruginosa (strain NIES-843) TaxID=449447 RepID=B0JWL2_MICAN +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDEPLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. 39-10 TaxID=1895745 RepID=A0A1M3E2X0_9FLAO +-sALSQRISEISAQKKATVAVSVIGIDFPFDLnNENADRKLPMLSVFKFHIALTAMHYVD +QGKLKLDQAFFVKKEELLPYSPLRDKQPDGNLSLAELLYYSVSLSDNNTTDILLRILGGP +KTVQQFMEEKKVKNLRIQYNEEEMHRNPKYFYGNYTSVKSLSKLYKSFYNGKILSKKSTE +YLYHILQQTTTGSNKLVQQLPPD-SVAHKTGSSGKDAENDSGIVALPNGRHYAISVFVND +SYESETVNCQMISDISKAVFD-- +>[subseq from] HGF-1 beta-lactamase n=2 Tax=Parabacteroides TaxID=375288 RepID=R5DKF0_9BACT +------DIKEVIQEKKATVGVAILY--QDKIF-TLSDNQQYPLMSLFKFHVTVAALKKMD +REHIPLDSTVYITREQMHEYSPLRNKYPNQGISLRDIITYTIIYSDNNTCDWLIDFAGGI +KKVDTFIKSLGIKKLNLTETEHSMHENIMNSYNNWSSPLSVVQLIKKIYTEKILSATSFA +FLEETMLNCSSGENKLKAGLPPNVKIGHKTGHSDRTSETDAGVIYLPDGERCYIAVLIKN +SLESDETNARIMADITRVIYH-- +>[subseq from] Penicillin-binding protein n=1 Tax=Aphanizomenon flos-aquae 2012/KM1/D3 TaxID=1532906 RepID=A0A0B0QL49_APHFL +---LKNSLQTLTTNADLMPGVFLLDLDNGGYV-DINSNASFAAASTIKIPILIAFFQDVD +AGKIRLDEILTLQKEMIVGGSGNMQYTPDSKYTALDVATKMITISDNTATNMLVAKLGGQ +EALNGRFRSWGLTTTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNVVSMRSRD +LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR +PNND-PRAAKLISSISSAAYEHf +>[subseq from] Beta-lactamase n=1 Tax=uncultured Bacteroides sp. TaxID=162156 RepID=A0A1C6IVT8_9BACE +-qKIEQQIDSLLKDKKATVGVALLA--NDEIVaVYNNQIHFPLLSVFKFHVGLAVLDKMD +KDHIGLDSLIEVKSSQLKPYSPLRDEFPDQDISLGELLKYTISKSDNNTCDILIEYVGGI +DQVNEYVKSLGIKDCNLAATETLMHTS-GDAYLNWSTPEEVVRLLNITDKQILFGTQYKD +FLQATMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQETDADNAAIIASISKIVYDT- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A649Z3N8_PSEAI +------------------------------------------------------------ +---------------------------PGGTLTLRELCRAAVSISDNTAANLALDAIGGA +RTFTAFMRSIGDDKTRLDRREPELNEATPGDARDTTTPIAAARSLQTLLLDGVLSAPARN +ELTQWMLGDQVADALLRAGLPRDWQIADKSGAGGHGSRSIIAVVWPPKRSAVIVAIYITQ +TAASMSASNQAVSRIGSALAK-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingobacterium hotanense TaxID=649196 RepID=UPI0011F363A4 +-eQLKIAIDSILAKYQAKVGIAIHNHDYTDSL-TVNGDFHFPFQSVYKFHLGIVILDQVD +KGKLSLDQPIKISKEAVTTYSPIKDKYPNGILPLREVLEYTIAASDNVGCDVLFELLGGP +EYVQKYFEDKGYSNLSIKLIEAVQQKEWNRQFENWTTVGSSNQILYDYYTKKLLSASSHQ +FLWDTMRGTTTGPDRLKGDLPKGTVVAHKTGYSGRNALNDVGVVSLPNGEVYYISVFVTD +SEEGEAGSAKIIAEVSAAAWKYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A166H5B8_KLEOX +---------------------------------------------------------RSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTNGNHRIRAAVPADWAVGDKTGTCGYGTAND-------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E1KFN0_9PLAN +--SLDSQLRALLDGHEGKAAVAIKHLTTGEQF-TFRENETMPTASLIKLAVMIETYRQAE +TGRVDLDRRITLKDEDKVAGSGILTPHFSAGISXRDAVQLMIAYSDNTATNLVLNQI-GI +KSTSETMEKLGFPNTKIHAQVFRRETVFPNRSRGSTTASETIGLLEQLYRAKLASPTSTQ +AMLTHLEACQD-RTKLPRLLNPQIRIAHKTGSVSR-VRADAGLLFXPSG-PIAICVLTSD +NKTDENAGDVLCAKVAEXAFHHf +>[subseq from] Beta-lactamase AST-1 n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A251Z4K1_9MICO +------------------------------------------------------------ +----------PIEAADILSYAPVTETRVGGTMTLRELADAAMTRSDNTAANLLLEALGGP +AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAAYLRAYALGDPLDADERT +LFTGWLTATQTGGTLVRAELPAHWTVGDKSGSGAYASRGDIAVIWRPDAAPLVIAVHSSK +DQQDADADDALISGAAKAAVE-- +>[subseq from] HGC-1 beta-lactamase n=1 Tax=Bacteroides plebeius CAG:211 TaxID=1263052 RepID=R5VVI2_9BACE +-qELYTNIHQFISQQKAEVGVAIIA-DGKDTV-TVENNRRYPLMSVFKLHQALAVGDYCK +KHQISFDTLLTVDSTDLQPYSPLREQYPHGGFSLKQLMEYTLHLSDNNACDILFKFTGGP +TMTDRYIRSLGVNDFSIQYTEDDMHRNLNLGYENWSSPLATAEVIEALFTRTLFDKPHQE +FIKEALITCQTGTSRIVHPLQKQVTVGHKTGTGDRNAINDAGFVQFPNGHRYTLVVFVKD +SQESMEDTEAIIAQISEMVYQTf +>[subseq from] serine hydrolase n=1 Tax=Aphanocapsa montana TaxID=327565 RepID=UPI00140AB42E +--QVKQEVEALAQAQGLETGLFFLNPETQEYL-SIRGSEAFPAASTIKLPILIAFFQEVD +AGRVKLDEQLVMREDLKVGEAGSMQSEVGSKYSALETADMMITISDNTATNMIMDRLGGN +QVLNERFKSWGLEQTRINQPLPDLEGT------NTISPKDLAILMMKVSQGDILTAHSRD +RALEILRNTVT-DTLLPQGLEPGAQIAHKTGDIGS-AVGDAGLIDMPNGQRYVAGIMVKR +PHND-PRAQELIRNISRLTYQAf +>[subseq from] Uncharacterized protein n=1 Tax=Myroides marinus TaxID=703342 RepID=A0A161S1I8_9FLAO +hqELNNKIKGVISNKNATVGVAIIY-DAKDTL-TVNNDHKYPTMSVYKFFQALNILDYMD +KHNISLDTEIYIKKEDLKEYSPLRDKSPKGEMSLRELIQYTASHSDNNISNLFFRSFIGP +KMTDLYFRSLGIQNFEIVSSEETMSLDFNNQYQNWITPLEATRILEMFRKEELLSPDYNN +FLRQAMIDTKSGQDKVKALLPKNTVVVHKTGMSLRAADNDLAIVYLPNGKQFSIAVFIMN +SKESDKTNASIIAEIAKLAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. S-NIH.Pt1_0416 TaxID=1920123 RepID=A0A430CSC7_9SPHN +-----SAINSLSASFSGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD +QGRARLDEPLVVRREDLTLHQPIAMLVKGDGTTVGELLTRALTQSDNTANDRLLTYVGGP +QVVRTMIANKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR +ILLDTMEASRTGHARLRAAVPSGWKIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD +TTEDIRLRQRLIQNVAAAVAS-- +>[subseq from] Serine hydrolase n=2 Tax=Sphingomonas paucimobilis TaxID=13689 RepID=A0A411LP21_SPHPI +-----SAINSLSASFSGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD +QGRARLDEPLVVRREDLTLHQPIAMLVKGDGTTVGELLTRALTQSDNTANDRLLTYVGGP +QVVRTMIANKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR +ILLDTMEASRTGHARLRAAVPSGWKIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD +TTEDIRLRQRLIQNVAAAVAS-- +>[subseq from] Serine hydrolase n=1 Tax=Richelia sp. TaxID=2053605 RepID=A0A3B9F8Y1_9NOST +----------LANNTKLTPGIFLVDLDNGNYV-DFNAANSFPAASTIKMHILVAFFQDID +NGKIRLYEQLTMEKGLIVGGSGNMGQKPGTKFTALEVATRMMTTSDNTATNMLIKRMGGI +DVLNQRFRSWGLSITTINNLLPDLKGT------NITSPKELGELMAMVSKGNLVTMRSRD +RIMDIMRRNTR-NNLLPAGLPKGATIAHKTGDIGS-MLADAGLIDLPTGKRYLAVVMVQR +PYND-PSAETLIKSVSRIACQQf +>[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa Ma_QC_C_20070823_S13 TaxID=2486246 RepID=A0A552GR55_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Beta-lactamase n=1 Tax=bacterium HR08 TaxID=2035403 RepID=A0A2H5VNL1_9BACT +--EVKARIERAIAASGAEVAVAYADLATGEEL-LLRADEPFHAASTMKVAVMLEVFRQAQ +EGRLSLEDRLVVANDSLADGSSFSYERIGQAVTIRELVRAMITRSSNLATNLLIERV-TA +ARVQQLMREMGIEGMRVLRGVEDRR-AFERGLNNTTTARALLLLFRRLAEGRAISPESSA +EMIRILLDQEF-NDGIPAGLPAGVRVAHKTGTIAR-IAHDAGVVYPPIGPPYVLVVLTRG +IA-DERDAHRLIAEISRLLYEH- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf62 TaxID=1736228 RepID=UPI00070174AA +--ALVATINALGGGFQGRVGIAVRSIDEGWVV-GHAMDQRMPQQSVSKLWVALTTMNAID +EGKLALATPVTITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTLSDNTANDKLLNLAGGP +VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLRHGMLLTPQSTS +WLLDTMSHTRTGRARLRAALPTGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD +TARPVQERQQLIQTVVSAIVA-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. CCH10-B3 TaxID=1768757 RepID=UPI0009E99F4E +-----AAVGTIARGFDGKVGIAVRSVDRDWMV-SANGDLPLPQQSVSKLWVAMAVLDARD +QGRLTLDDPVTVTREDLTLHQPIAAMVRGDGTTVGDLLQRALTESDNTANDRLLRLIGGP +DAVRAFIARKDLGTIKFGPGERLLQSAYVADPPDGAAPIAIAGALAKLKRGALLSPGSTQ +YLIGTMESSKTGRQRLRGAVPIGWSFGHKTGTGQTAGYNDVGILTAPDGRSYALAVMIGD +TPRPIAERQALMQSVVAAVVA-- +>[subseq from] AMIN domain-containing protein n=1 Tax=Tolypothrix sp. PCC 7910 TaxID=2099387 RepID=UPI001427814C +-kALEPQIKALMSRYSLTTGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFFQDLD +AGKVRLDEKLTMRGDLVTNGSGDMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA +AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNNKLVSPSSKE +QALDILRHTTV-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKHYLAAIFVKR +PYKD-TRGRDFIRQVSQLVYNY- +>[subseq from] HGB-1 beta-lactamase n=1 Tax=Alistipes sp. CAG:268 TaxID=1262693 RepID=R6W363_9BACT +-eQFERRIDRILEPCEATVGVAVLAPD-GTPI--TRNDRPLPMLSVFKFPVALAVLDRAV +REGIPLSTPVAVGPEWLDSYSPMRDSLPPQGLPLGRLLAYAVSQSDNIACDRLIDFAGGP +GAVDRYLKRLGITEIRITATERTMHLATENQRINTARPSALCSLFDRFLQGELLPQRETA +WLRGLLEGCATGRNKLRAGLPPEVRLGHKTGSSDRTADNDAGYVVLPDGRHYCITVLVTD +SHHDDARNAGVIAAISEAAYEYf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus antibioticus TaxID=2570228 RepID=A0A4U2Y0U8_9BACL +---WQQAVENELKEAPGIFGIAAVHVETGETA-GHLDEELFQLASAFKIPIMVTLMSEVE +AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELIGGI +DKVNKHMHELGLSQIHLRHNCWELLNSMPTCDNNVATPAELNRLLIMIARKEILTETSCE +LMQDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR +GVTDTEAAELTIARVAKAIYE-- +>[subseq from] AMIN domain-containing protein n=1 Tax=Nostocales TaxID=1161 RepID=UPI000BBCC8BD +-kALEPQIKALMSRYSLTTGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFFQDLD +AGKVRLDEKLTMRGDLVTNGSGDMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA +AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNNKLVSPSSKE +QALDILRHTTV-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKHYLAAIFVKR +PYKD-SRGRDFIRQVSQLVYNY- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Microcystis aeruginosa SPC777 TaxID=482300 RepID=S3JDP8_MICAE +--SLNQKLQALAVKYKLQTGALFIDLDNGAYA-NFRGDTVFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Leaf28 TaxID=1735695 RepID=A0A0Q4JQ43_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIIRSDNQATDQLLAALGGP +VAIQRWLSSQNIPGIRMDRSIAQLLRGHLADIKDVATPIAMVTLLNKLDNGTVLTPQSRA +FLLGLMGRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG +GR----DRQPVIAEVARVIYNRf +>[subseq from] Serine hydrolase n=1 Tax=filamentous cyanobacterium Phorm 6 TaxID=2107706 RepID=A0A2T1FAR7_9CYAN +----KTQVQILATENTLTAGIFLVDLDTGSYL-NFNGDTPFASASTIKLPILVAFFQAVD +EGKVQLDQMLTLKAEHIVGGSGEMQDAPGKKYSALEVARKMIVVSDNTATNMMIELLGGA +EVLNQHFANWGLRATVLRNNLPDLEGT------NTSSPKDLINIIAQVDRGNLVSVKSRD +RILQIMRQTQN-DSLLPRGLGEGAVIAHKTGNINI-MLADAGMVDLPNGKRYLVAVMVKH +PAETEKPAQTLIRDISRMSYRY- +>[subseq from] Serine hydrolase n=1 Tax=Microcystis flos-aquae TF09 TaxID=2060473 RepID=A0A3E0LBT7_9CHRO +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTVFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Microcystis aeruginosa NIES-4285 TaxID=2497681 RepID=A0A402DAZ1_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTVFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] serine hydrolase n=1 Tax=Synechocystis sp. PCC 7509 TaxID=927677 RepID=UPI000311D215 +---LKAAVQQLGKNKGLTPGAFFVDLDTKNYL-DWNGSLPFAAASTIKVPVLVAFFQDVD +TGKIRLDEKLTIEKKIIGGGSGGMQYPLGTKYTALNTATQMIVVSDNTATNMLIKRMGGI +KVLNERFQAWGLESTKINNLLPDLTGT------NTTSPKDMGNLMSLVDRGELMTLRSRD +RLLEIMRRTKT-RTLLPQGLGEGAIIAHKTGDIGS-MVGDVGLVDMPNGKRYIAVAMVKR +PHND-SRAQELIRQISRLSYQQf +>[subseq from] serine hydrolase n=1 Tax=Trichormus sp. NMC-1 TaxID=1853259 RepID=UPI0008DBE919 +-------VQNLAAQANLTPGVFMVDLDTGAYV-DINSNASFSAASTIKVPILIALFQDVD +AGKIRLDEMLTLQQEMIAGGSGTLKSRVGTQYSALEIATKMITISDNTATNMLISRLGGK +DILNERFRTWGLATTMIRNSLPDLQGT------NTTSPRELGNLISMINQGNIVSMRSRD +LMLNIMSRTER-DHLLPSGLGQGSKAYHKTGDIAT-MLADAGLIDIPSGKRYIAAVMVQR +PTND-PRAEKLISSISAAAYQQf +>[subseq from] Class A beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V2DBU3_9BACT +-qNMAQDIEKIIKEKQASVGVAVIH--NDGIF-TIANDDKYPTMSVFKLHVAVTALKKME +NENIPLDTKAYIEQKEMLKYSPLRDKYPDQGISYRDIIDYTVKISDNNTCDWLIRFVGGI +NKVNSYIKSIGIKEMNFTETEESMHTDIMRCYNNWSTPLAVAQLLKKIYAENLLAKEHFT +FLETSMLNCVSGKNKLIAGLPHDIKFGHKTGHSDRTSEADAGVIYLPNGEKCYIVVLIKD +SRESDDDNAKIMADISNAVYRY- +>[subseq from] Uncharacterized protein n=1 Tax=Erythrobacter luteus TaxID=1581420 RepID=A0A0G9N1B3_9SPHN +-qELTGLLETIAADFGGTTGIAVVDLEDGWST-GVNADALLPQQSVSKLWVALTALDRVD +RGTLTLGDRITIARQDLTVHQPIREEVLRAGINPLDLMTRAITRSDNTANDALLWAVGGP +DAVRAMLRDKGIAKVRFGPGERLLQSSYLADPVDGASPRAIATALARLARGELLAPPTTK +LMLDTLRETRSGPRRLKGGLEQGWSIAHKTGTGQYYGYNDVALLFAPDGRTYAVAVMIGE +TRQGVPGSTAMMQKVTRAVED-- +>[subseq from] Serine hydrolase n=2 Tax=Sphingomonas sp. Leaf22 TaxID=1735687 RepID=A0A0Q4GT69_9SPHN +--ALVATINALGGGFQGRVGIAVRSIDEGWVV-GHAMDQRMPQQSVSKLWVALTTMNAID +EGKLALATPVTITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTLSDNTANDKLLNLAGGP +VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLRHGMLLTPQSTS +WLLDTMSHTRTGRARLRAALPTGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD +TARPVQERQQLIQTVVSAIVA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A1W6AKY9_KLEOX +------------------------------------------------------------ +-----LNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGNETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYG------------------------ +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Nostocales TaxID=1161 RepID=A0A1Z4N466_9CYAN +-kALEPQIKALMSRYSLTTGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFFQDLD +AGKVRLDEKLTMRGDLVTNGSGDMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA +AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNNKLVSPSSKE +QALDILRHTTV-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKHYLAAIFVKR +PYKD-SRGRDFIRQVSQLVYNY- +>[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia occulta TaxID=1867263 RepID=A0A1T3M9C8_9FLAO +-pQLKKTLESIISGKKSIVGISVMSPDEKEMT-GINANQMLPMLSTVKFPLALAALHEVE +KGKLSMNQKLFIKKEELLDWSPFKEKYPAGNITLEEALKWTVSYSDNNLTDILIRLIGGP +ETVQEFMDS---SSFIIKNNEEGMHKDWDSQFINKITPNFAVLLLQEFSNSKILNKTNTQ +WLYNAMLNNVSGKKRLKGNLPTGVKVAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN +TYESFDDSEKIISDIGRAAYDYy +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2E7AQ56_9BACT +------AXLAIAQRFPGDVGVYVHHIESGMET-GIDEDTPYGMASTYKVPILVELMTRVE +AGDLSLDDRVAVEAEDQHIGSGLLSTLWAPGMSLRNIATFMIILSDNSATDMLIDRL-GA +DQITAXMRSLGFQNIRVDRTTLELILDFYGGDKDKASARDMTELLVMISEGTAVSRGSSE +VIMEILARTQTGANRLRGLLPPGYSIAHKTGTIGR-IVNDVGVITMPGDGRFAISVFTLA +NEADTELGEHTIAEIARTAYDFf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9G449_9BACT +-qKLEAAIQDIDRNLDGVLAVAILDLSTGQKY-LFHADEVLPTASSIKIAILAELYHQVQ +QGKLKLGDLYTLQSSDLVGGSGVAGALTPGVLTLRDVAALMISVSDNSATNVIIDRI-GM +ENVNALLDSLGLTHTRLRRKMMDVKAA-AEGRENIATPREMMLLLENLYRGKVLNKQFTE +EFFNLLSIHKE--SYIPRELPEDLRVANKPGELE-GVRNDSGIVFAGKR-PYVISVMTTY +LRREH-DGGEAIIRISNAAYQMf +>[subseq from] Beta-lactamase n=1 Tax=Parabacteroides sp. CAG:409 TaxID=1262913 RepID=R7J5J6_9BACT +--DLGARLKETLAGKAATVGVAVI-FNGNELV-TVNNMYRYPMMSTFKFHQALSVLDYLN +KNEKDLNTEILVKQSQLLAHSPMRDANPKGNMSVGDLLKYTLIDSDNNACDVLFDLIGGP +KVTEKYIHKLGIEDVAISQTESLMHANPDNCMLNWCKPSSAVLLLETFLQQPICNKSQKL +FIQRAMADCSTGKDKLKAGLPKDVLLAHKTGSSDRNADNDMGFVVLPNGQYYTIAVFVMN +SRESDKKNARIIADVSRVVYEYf +>[subseq from] Serine hydrolase n=2 Tax=Microcystis TaxID=1125 RepID=A0A552L7C6_9CHRO +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDEPLVATKDVMASGSGDMQYLGANKYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Chlorogloea sp. CCALA 695 TaxID=2107693 RepID=A0A2T1ECA8_9CHRO +----KTAVQQLGKNKGLTPGAFFIDLDTHNYL-DWNGSLPFAAASTIKVPVLVAFFQDVD +AGKIRLDEKLTLQKKLIGSGSGGMQYPLGTKFTALNTATQMIVISDNTATNMLIDRMGGI +AKLNERFQSWGLVSTKINNPLPDLTGT------NITTPKDMGELMSLVDRGELMSLRSRD +RLLEIMRRTKT-RTLLPPGLGEGAIIAHKTGDIGS-MVGDVGLVDMPNGKRYIAVAMVKR +PHND-SRAQELIRQISRTTYQHf +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. 2B10 TaxID=2483355 RepID=UPI000F7AFF0B +--ALAAAINALGGGFQGKVSIAVRSIDEGWVV-GHAMDQRMPQQSVSKLWVALTMMNAID +EGRYALTAPVTITRSDLTLHQPIAYLMKDGATTVGDLLRRALTMSDNTANDKLLNLAGGP +VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLHHGMLLTPQSTQ +WLLDTMSHTRTGRARIRAALPAGWSVAHKTGTGQTAGFNDVGILTAPDGKAYAVAVMIGD +TARPVPERQQLIQTVVSSIV--- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9XQV0_9BACT +-qKLETSISNIDNTLDGVMGVAILDLTGGQKF-LLHADDVFPQASSIKIAVLAELYHQAQ +QGKLKLADLYTMQQSDLVPDSDIMGGLTPAIITLRDLATMMVAVSDNSATNVLIDRL-GM +ENVNALMDSLGLPHTRLRRKMMDLKAA-SEGRENISTPREMMTLLESIYRGKVFNKEMTD +DFFKMLSTHK--DSFIPRELPDGLKIANKPGELE-AVRNDSGIVFAQNR-PYVICVMTTY +LHR-ERDGEAAITKISAEAFSMf +>[subseq from] serine hydrolase n=1 Tax=Cronobacter turicensis TaxID=413502 RepID=UPI00131A485A +-----------------RVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPEQNEAIPNDERDTTMPVAMAT----------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Alistipes sp. CHKCI003 TaxID=1780376 RepID=A0A143XT01_9BACT +--RLERRIDRIAERCDARIGVAVTT-PAGLLL--SRNDTLLPMLSVFKFPVALAALDRME +RDTLPLTHPVTVGFERLDRYSPMRDSLPAGGVALGALLRYAVSASDNIACDLLIDFAGGP +AAVDDYVRSLGIDGMRILTDERRMHLTVGNQRLNAARPSAVCALFDRFLRGGVLSAAHEA +FLRSLLVSTETGADKLKAGLPARTVIGHKTGSSDRTADNDAGYVLLPDGRSYCIAVFVTD +SEEDDAANAAVIAAISAAVYDHf +>[subseq from] Putative beta-lactamase protein n=1 Tax=Microcystis aeruginosa PCC 9717 TaxID=1160286 RepID=I4FL98_MICAE +--SLNQKLQALAVKYKLKAGALFIDLDNGAYA-NFREDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=2 Tax=Microcystis aeruginosa TaxID=1126 RepID=A0A2I9CHN6_MICAE +--SLNQKLQALAVKYKLQTGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas insulae TaxID=424800 RepID=UPI0013D44567 +--QLTTAIDTLARTFDGKFGIAIRAVDEGWTIaSPGARTRMPQQSVSKLWVAMTLMDLRD +QGKARLDDPVLVRPEDLTLHQPIAMLVKGAGTTVGELLTRALTHSDNTANDRLLTYVGGP +MAVRAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADAIARLARGELFTETSTR +ILLDTMGASVTGRARLRAALPAGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +SRRPIRERQQLIQSVAAAVADY- +>[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa EAWAG127a TaxID=2529855 RepID=A0A5J5LUS1_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETASKMNVISDNTATNMLIKRMGGK +EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=2 Tax=Sphingomonas sp. Leaf67 TaxID=1736230 RepID=A0A0Q4Q247_9SPHN +--ALVATINALGGGFQGRVGIAVRSIDEGWVV-GHAMDQRMPQQSVSKLWVALTTMNAID +EGKLALATPVTITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTLSDNTANDKLLNLAGGP +VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLRHGMLLTPQSTS +WLLDTMSHTRTGRARLRAALPTGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD +TARPVQERQQLIQTVVSAIVA-- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus centrosporus TaxID=54910 RepID=UPI000F0A4441 +--SLQKKLESVLSETSATFGVTVKHLDTNEEA-RINSDQYFQMASTFKVPILATLFRDVV +EGRLSLETRIRLTEDDLVSGSGVLKEFLPGAVAVKDLATLMIIVSDNLGTDKVLELV-GI +ERVDAFMKELGLAHISIQNSCWDLLSFQATLENNVSTPDDMCQLLALIASGELVSQEACD +GILDVMKRQQL-RNRIPYLLPDKTIIACKSGTIGS-VVNDVGIVYLPEGGAFAIAAFSHG +N-ESMKAGERIIAQLTRTAYDHf +>[subseq from] Putative beta-lactamase n=1 Tax=Planktothrix agardhii NIES-204 TaxID=282423 RepID=A0A2Z6CDH0_PLAAG +---LKTAILGLAKDLKLKPGVFLVDLDTGNYV-DIQGQEAVPAASTIKLPILVSFFQAVD +EGRIRLDEVLTMEEKHVAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI +ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINQGKLVSLKSRD +FMLRIMQQTRN-RSLLPRGLGDGAFIAHKTGNIDS-VSGDVGLIDMPNGKRYLVGVLVQR +EA-DDPQANELIRQISSTIYQYf +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7PID6_9BACT +--RLTDLLQPVIAAHQGAVAVSVKHLKTGATF-AHRADEPMPTASLVKFPVMVAAYQQAA +DGMLDLAKSVVLKEEDKVPGSGILTKHFSAGLSVRDAIRLMIAYSDNTATNLVVDQI-GL +AATTDLMTKWDFPHTRLHAKVYRGDTSIAPDRSGSTTAGEMLRLLERLHRKELVSEEASQ +QMIDHLLACDD-KQRLAKFLPAGTKVALKTGSVS-ASRTVAGIIESPSG-SIAVCVLTEN +NKIDDNAAQLLSAEIARQLWQHf +>[subseq from] serine hydrolase n=1 Tax=Zavarzinella formosa TaxID=360055 RepID=UPI0002E82AA0 +---LEQKISALAKAHEGRVSVAVKHLGTGETI-LLNSGEVMTTASLIKFPIMAEAYAQEL +AGKVKLDQKITLTKEDMVPGSGILTEHFSPGMSLRDAIRLMIVYSDNTATNLVLDQV-GI +KAVNDRMAAMGCGETRINAKVFKGSTRTKQYGLGSTTAKDMVSLLELLHREELVSPAASK +AMLAHLKKCED-KDKFPRRLPPSVVVAHKTGSVNE-ARTDAGILYFPGG-PVAVCVLTNQ +NKTPDNAGNKLCADIALAVFEHy +>[subseq from] Beta-lactamase n=3 Tax=Alphaproteobacteria TaxID=28211 RepID=A0A2T5GSJ5_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIIRSDNQATDQLLAALGGP +VAIQRWLSSQNIPGIRMDRSIAQLLRGHLADIKDVATPIAMVTLLNKLDNGTVLTPQSRA +FLLGLMGRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG +GR----DRQPVIAEVARVIYNRf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas glacialis TaxID=658225 RepID=A0A502G4J0_9SPHN +------------------------------------------------------------ +----------------------------------AKVLELMIVRSDNQAADQLLAAVGGP +VTVQQWLSSHAITGIRVDRTIAQLLRGHLADSKDVATPTAMVALLYKLTNGTVLTPQSSA +YLFDLMRRCQTGTRRIRALLPTGTLVEDKTGTLD-GVTNDVGFITMPDGHRVAVAVFARG +GR----DRQPGIAAVARVIYDRf +>[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa 11-30S32 TaxID=2358142 RepID=A0A510PNI5_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDEPLVATKDVMASGSGDMQYLGANKYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI0014482306 +-----NSLQTLTANADLMPGVFLLDLDNGGYV-DINSNASFAAASTIKIPILIAFFQDVD +AGKIRLDEILTLQKEMIVGGSGNMQYTPDSKYTALDVATKMITISDNTATNMLVAKLGGQ +EALNGRFRSWGLTTTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNVVSMRSRD +LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR +PNND-PRAAKLISSISSAAYEHf +>[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa Ma_AC_P_19900807_S299 TaxID=2486264 RepID=A0A552AHI4_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSANIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] AmpC n=1 Tax=Planktothrix agardhii NIVA-CYA 126/8 TaxID=388467 RepID=A0A073CD29_PLAAG +---LKTAILGLAKDLKLKPGVFLVDLDTGNYV-DIQGQEAVPAASTIKLPILVSFFQAVD +EGRIRLDEVLTMEEKHIAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI +ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINQGKLVSLKSRD +FMLRIMQQTRN-RSLLPRGLGDGAFIAHKTGNIDS-VSGDVGLIDMPNGKRYLVGVLVQR +EA-DDPQANELIRKISSTIYQYf +>[subseq from] Beta-lactamase class A n=1 Tax=Synechococcus sp. PCC 7502 TaxID=1173263 RepID=K9SNY9_9SYNE +--ELTTKINALTKSQDITVETYLTDLDSGGYV-NIKGSEAIASASMIKIPVLVAFLQDVD +AGKARLDEQLVLSKDVIVGESGGLQEPVGTKISALETITLMIIISDNTATNMIIKRIGGI +EEANQRFLSWDLTSTVIRNPLPDLTGT------NTTSPEDLVNLLSMVEQGKILSPRSRD +RLMDIMHRTKT-NTLLPQGIPPDARIAHKTGDIKS-VVGDAGIIDMPNGKRYIISAIAKR +PSND-QRANELIRQISRTVYTH- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteriales bacterium 13_1_40CM_3_55_5 TaxID=1803468 RepID=A0A1Q7MRI0_9BACT +-qKLESTINDIDRSLDGVIGVAILDLTSGQKF-LLHADEVFPQASSIKIAVLAELYHQAQ +TGKLKLNDLYTVQASDLVPDSDIMGGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GM +ENVDGLMTSLGLTRTRLRRKMMDLKAA-SEGRENISTPGEMMILLENLYRGKVLNKEMTE +DFFKVLSTHKS--SFIPRELPEGLKIANKPGELER-VGNDSGVVFAEKR-PYVICVMTTY +LQR-ERDGEEAISRISLAAYRTf +>[subseq from] Putative beta-lactamase n=2 Tax=Parabacteroides johnsonii TaxID=387661 RepID=B7BBD2_9BACT +------DIKEVIQEKKATVGVAILY--QDKIF-TLSDNQQYPLMSLFKFHVTVAALKKMD +REHIPLDSTVCITREQMHEYSPLRNKYPNQGISLRDIITYTIIYSDNNTCDWLIDFAGGI +KKVDTFIKSLGIKKLNLTETEHSMHENIMNSYNNWSSPLSVVQLIKKIYTDEILSATSFA +FLEETMLNCSSGENKLKAGLPPNVKIGHKTGHSDRTSETDAGVIYLPDGERCYIAVLIKN +SLESDETNARIMADITRVIYH-- +>[subseq from] Beta-lactamase OXY-2 (Penicillinase) n=2 Tax=Xenorhabdus nematophila TaxID=628 RepID=D3VGM9_XENNA +------------------------------------------------------------ +-------------------------------MTLGELSAATLQYSDNAAMNLILNQLGGP +HEVTKFARTLGDNSFRLDRKEPELNNVIPGDERDTSTPRAMADDLYHLALGNALDATQRE +QLITWLKGNTTGAASIRAGVPEGWIVGDKTGRCDYGSTNDIAVIWPVNQPPLILVTYFTQ +PDKEASARPDVLAAAARIMTQH- +>[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. OK042 TaxID=1884381 RepID=A0A1I3SF15_9BACL +--SLQKKLESVLSETSAAFGVTVKHLDTNEEA-RINSDQYFQMASTFKVPILATLFRDVV +EGRLSLETRIRLTEDDLVSGSGVLKEFLPGAVAVKDLATLMIIVSDNLGTDKVLELV-GI +ERVDAFMKELGLAHISIQNSCWDLLSFQPTLENNVSTPDDMCKLLALIASGELVSQEACD +GILDVMKRQQL-RNRIPYLLPDKTIIACKSGTIGS-VVNDVGIVYLPEGGAFAIAAFSHG +N-ESMKAGERIIAQLTRTAYDHf +>[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa FACHB-524 TaxID=2486203 RepID=A0A3N0WE73_MICAE +--SLNQKLQALAVKYKLQTGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Beta-lactamase n=2 Tax=unclassified Calothrix TaxID=2619626 RepID=A0A2H2XV80_9CYAN +---LKSAIQSLAANNNLTPGVFAADLENGSYV-DFNGGAMFSSASTIKLPILIAFFQDVD +EGKIDLSETLSTSKSTIVGGSGDMQNRPGTKYNILEVATKMMIISDNTATNMLIERLGGV +EKLNQRFRNWGLNTTSLRNTLPDIPGT------NTTSPKELGSLMAMITKGNIVSQESRG +RILEIMRGTFK-DTLLPVGLGQGATIAHKTGEIGS-LLADAGLVDLPSGKRYIVAVMVQR +PRND-VSAEKLINGISRVVYQQf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Microcystis aeruginosa Sj TaxID=1979544 RepID=A0A2Z6UQ53_MICAE +--SLNQKLQTLAVKYKLQAGALFIDLDNGAYA-NFRGDTVFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. YJ09 TaxID=1104779 RepID=UPI0012D2BE1F +------------------------------------------------------------ +------------------------------GVPVRTLMAKMLIHSDNHAADVLFKDVGGP +RAVHHWLVQNGIHGVRVDRTIAQLLAAKRWDVRDSSTPKAMVELLRRIYRGELISAQSRN +YLLAEMAKCQTGRNRMKWLLPEGTPVEHKTGTLN-GLTDDVGFITMPDGHRIAVAIFARG +GS----NRPRTIAQAARAIYDGf +>[subseq from] Serine hydrolase n=1 Tax=Microcystis panniformis Mp_MB_F_20051200_S9 TaxID=2486223 RepID=A0A552Q431_9CHRO +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=2 Tax=Microcystis aeruginosa TaxID=1126 RepID=A0A552BS55_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Genome sequencing data, contig C307 n=3 Tax=Microcystis aeruginosa TaxID=1126 RepID=I4GIX2_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] serine hydrolase n=1 Tax=Microcystis aeruginosa TaxID=1126 RepID=UPI000468934F +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Microcystis sp. Msp_OC_L_20101000_S702 TaxID=2486218 RepID=A0A552CC34_9CHRO +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Apibacter sp. B3706 TaxID=2656760 RepID=UPI001407567D +-kSLEKKIHSITKNKKATVGVAVI-FDGKDTL-TVNNDMEYPAMSVFKFHQALALLDYMN +NNLLSLESNLYLKKSDIKKYSPLAKEYPEGNIPIGDLLNYTVSKSDNNASDALYYYMSGT +KMTDLYLRTLGSKNFSIQATEEEMNKDFNNQYINWTTPLEAARLLDIFINKDIFCKNYKD +FLFQAMTESETGSDKLKALLPKKVLIGHKSGSSSRNADNDIGFVYLPNGKQYSIAVFIKD +SKEDDKTNARIIADISQVVYNFy +>[subseq from] Putative beta-lactamase protein n=1 Tax=Microcystis aeruginosa PCC 9807 TaxID=1160283 RepID=I4H0J5_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa Ma_QC_B_20070730_S2 TaxID=2486256 RepID=A0A552D6B0_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9XSH6_9BACT +-qKLESKIEQVDRNLDGVMGVAIEDLTTGDHY-FLREDEVFAQASSIKITVLANLYLQAQ +QGKLKLTDLYTVQSSDLVPDSDIMNGLTPGIVTLRDLATMMVAVSDNSATNVLIDRV-GM +QNVNAMLDSLGLSHTRLRRKMMDLEAA-KQGRENISTPREMMTLLDAIYHGKLLNKESTE +DFFKMLSTNKQ--SFIPRDLPPDLKVANKPGELE-AVRNDSGIVFVAGR-PYVICVMTGF +LR-NEREGEEAITKVSLETWRMf +>[subseq from] hypothetical protein n=1 Tax=Planktothrix TaxID=54304 RepID=UPI00041C7362 +---LKTAILGLAKDLKLKPGVFLVDLDTGNYV-DIQGQEAVPAASTIKLPILVSFFQAVD +EGRIRLDEVLTMEEKHVAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI +ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINQGKLVSLKSRD +FMLRIMQQTRN-RSLLPRGLGEGAFIAHKTGNIDS-VSGDVGLIDMPNGKRYLVGVLVQR +EA-DDPQANELIRKISSTIYQYf +>[subseq from] Putative beta-lactamase protein n=1 Tax=Microcystis aeruginosa PCC 9809 TaxID=1160285 RepID=I4HZ79_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDEPLVATKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter neustonensis TaxID=1112 RepID=A0A192D2A8_9SPHN +--SFEQRIAQLANPALGRIGVAAIDLATGEEV-MVLGDQLFPMASTSKVAVAATFLEMVE +KGRFSLSSEFPLLLPVASAYSSAKAPVRAGQLPAIDLIEMMITRSSNPATDALLAAVGGP +GVVNDWIRRQGISNFSINRDIATLVRATFIDPRDAATPRTMAKLLAGIYGGQYLSDDSRR +VLLGAMSRTVTGKRRIPAHIPLDARVSHKTGSLNN-TSSDIGLIECPDGRVIAVAIYVTG +QG-TKAAREERIAAIARALYDGf +>[subseq from] Class A beta-lactamase n=1 Tax=Alistipes putredinis TaxID=28117 RepID=A0A1Q6FD30_9BACT +--DLSYRLKKVIKDKKAEIGIAVI-LDAQDTV-TVNNDDRYPLMSVFKFHQALAVADYLD +RNGLTPDTEIFIPEEELVPYSPLRKEFPEGELSVSRLLEYSLQLSDNNACDILFEHTGGP +AATDRYVRSLGLCNFAIAATEQQMHDDPQTCYENWSTPLEAAALLELLVTEQILTPTLRE +MILQNLINCKTGADRLPKPLSTGAVIGHKTGTSNRDGTNDLGFVILPDDTRYTIAVFIKD +SAENPETNARIIADISETVYRY- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter arachoides TaxID=1850444 RepID=UPI001038F7E0 +--ELTALLGTIASDFGGTMGIAVVDVDSGWTT-GINDRKMLPQQSVSKLWVALTALDQVD +RGRLTLGKRVVIEPEDLTVHQPLREQVLRTGTDPLDLLTRALTRSDNTANDALLWTVGGP +DAVRAMLREKAIANVRFGPGERLLQSSYLADPVDGATPRAIATALARLARGDLLSPASTE +RMIAILRETHSGPRRLKGGVGTGWSIAHKTGTGQYYGYNDVALLFAPDGRAYAVAVMIGE +TRKGVPQSMAMMQAVTRAVED-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas wittichii TaxID=160791 RepID=UPI0004AA3996 +--ALDAAIDRLGRRFPGDVGLAVRDVQTGWTS-HHRGLDYFPQQSVSKLWVSLTALDEVD +SGRLDLSRALTVTAKDLTLHQPIRALALRPGTTGDDLMVRALTQSDNSANDRLLHQVGGP +DAVRATLRGKAIAGIRFGPGEPRLQAEYLADPIDGATPIAMVDTLARLRRGDLLSPASTA +KMTAIMEETRTGALRLKAGLKPGWRLAHKTGTGQQAGYNDVGILTSPEGRSYAVAVMIGR +TGRPLAERMKLMQSVVAATI--- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. (strain K31) TaxID=366602 RepID=B0T712_CAUSK +--TMTVQFQEIANRVPGSLGVAVEDLSTGQII-SFNGEKRFPLQGVFTAPLGAAVLAEVE +AGRLRLNETLRIEDVDLSPHSPIADAWPSRDYTVQELLERAVGDSDNTAADVLMKRIGGP +GAVTAWLQGRKVAPLDIDRYERQLQPAYLADPRDTATPLGALRFLEAMNQAELLGPDSRR +LLGGIVSQASSGPNRLRAALPDGARLAHKAGTARTDVVNDIGVYTLKDDRKFAVVVFVSG +SRLSVAEQEKAIADVGRVVMK-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas wittichii TaxID=160791 RepID=UPI00037C5852 +--ALDAAIDRLGRRFPGDVGLAVRDVQTGWTS-HHRGLDYFPQQSVSKLWVSLTALDEVD +SGRLDLSRALTVTAKDLTLHQPIRALALRPGTTGNDLMVRALTQSDNSANDRLLHQVGGP +DAVRATLRGKAIAGIRFGPGEPRLQAEYLADPIDGATPIAMVDTLARLRRGDLLSPASTA +KMTAIMEETRTGALRLKAGLKPGWRLAHKTGTGQQAGYNDVGILTSPEGRSYAVAVMIGR +TGRPLAERMKLMQSVVAATI--- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE02838 +--ALQQRLEKLATGKDARIGICALD-QAGTSV-CVRGDERFSLQSVVKLIAGAATLDAAD +HGAVNIEDPIIIRSENLSLKQPLAKIVERNGTNAGDLVRRAIVESDSAAVDILINRLGGT +GKINSFLAGKAISGIRIDRDERHLQTAYQKDPRDTATPRAMTEFLAALMNGKLISTSSTD +RLLAIMNETSTFPDRLRAGVGNDWSVAHKTGTSPNVATNDVGILTAPDGGKVAISVFVAD +SRETPTRRATIIASAAQAVTEAy +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9V0Z9_9BACT +-qKLENSIAEVDRNLDGAMGVAILDLTDGHKY-LLHANDVFAQASSIKICVLAELYRQAQ +QGKLKLTDVYTVNASDLVQDSDIMGGLTPGVITLRDLATMMVAVSDNSATNVLIDRI-GM +ENVNTMLDSLGLTHTRLRRKMMDLKAA-AEGRENVSTPAEMMVLLESLYRGKVLNKEMTD +DFFKVLATHK--DSWIPRDLPDDLRIADKPGALE-GVRNDSGVIFVEKR-PYVLCVMTTY +LRR-ERDGEDAISKVSLVAWRMf +>[subseq from] Putative beta-lactamase protein n=1 Tax=Microcystis aeruginosa NIES-87 TaxID=449440 RepID=A0A2H6L070_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVASKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKAADIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Penicillin-binding protein, transpeptidase n=1 Tax=Planktothrix rubescens TaxID=59512 RepID=A0A1J1L5F7_PLARU +---LKTAILGLAKDLKLKPGVFLVDLDTGNYV-DIQGQEAVPAASTIKLPILVSFFQAVD +EGRIRLDEVLTMEEKHVAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI +ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINQGKLVSLKSRD +FMLRIMQQTRN-RSLLPRGLGEGAFIAHKTGNIDS-VSGDVGLIDMPNGKRYLLGVLVER +EA-DDPQANELIRQISSTIYQYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. D43FB TaxID=2017595 RepID=A0A2A3N0L7_9SPHN +--RLIAQFQRFATLTDGTVGITVRDLTSGESL-SLNGDTLFPMASAYKVAVAGKIFAMID +AGQLALTDIVPRDVATMGP---------GAPLPVARLLDLMLTQSDNEATDMLVARAGGP +TAVNGWVAGLGIKGLRVDSNTADLLYAFARDPRDSATPTAMTDLVAAIRTGRALSPASTH +AFITIMERCRTGKARLPGMLPPGTTIAHKTGTIN-GTGNDTGVITLPDGRMFAITVFVMQ +DHRGRVMRDRIMAEAARAAYDYf +>[subseq from] Putative beta-lactamase n=1 Tax=Erythrobacter sp. SD-21 TaxID=161528 RepID=A5P823_9SPHN +-tALQAELQDIGEGFDGVVGIAVTEADSLATM-SYNGSAPMPQQSVSKLWVTMTALDRVD +EGALDLSERVTIGREDLTVYQPIRNIVKARGTDYGDLMDRAITQSDNTANDRLLRYVGGV +QAVEGFLRRNAIEGVQFGADERTKQSAYLDNPMDGATAEGLARALARLARGDLLSENSTQ +LLLETMSRTKSGPRRLKGGVPAGWEFGHKTGTGQQSGYNDVGILTAPDGTRYALAVLIGQ +TRASYAARMAMMQEVTQRVVRY- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus panacihumi TaxID=497735 RepID=A0A3M8CZS6_9BACL +--NLQQKLESVLSESSGTFGVAVKHMGTGEEA-QIRAEQYFQMASTFKVPILAALFRDAD +AGLVSLEQRYRLSEADLVPGSGVLKEFLPGAVALKDLATLMIIVSDNLATDKVLEII-GK +ERVEAYMRELGLTQISIKHDCWELLSFQASPENNVATPADMGRLLELIGTGKLASEQASD +GVLDIMKRQQL-RNRIPYLLPDETIIACKSGTVGH-VVNDVGIVYLSDKGAFAIAVLSSG +NP-SVKEGERVIARLAQTAYEHf +>[subseq from] hypothetical protein n=1 Tax=Planktothrix agardhii TaxID=1160 RepID=UPI0004123AC8 +---LKTAILGLAKDLKLKPGVFLVDLDTGNYV-DIQGQEAVPAASTIKLPILVSFFQAVD +EGRIRLDEVLTMEEKHIAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI +ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINQGKLVSLKSRD +FMLRIMQQTRN-RSLLPRGLGEGAFIAHKTGNIDS-VSGDIGLIDMPNGKRYLLGVLVER +EA-DDPQANELIRKISSTIYQYf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Microcystis aeruginosa NIES-4325 TaxID=2569534 RepID=A0A5J4F560_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKAADIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Class A beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1W5MZV5_9BACT +---------------NVNVGIATL--KDKDLV--VVNNKKYPLLSVFKYFVAIKVLKYID +QKHISLDTKITINQNDMQTHSPMIKDYKNYPITLAQLLEYMISQSDNNACDILIDYSGGI +NELEKFIHELGFNDISIKVNEKDMNSDIYNQYLNTSTPKDIVLMMKRVKDNNILSSSSFA +FLENIMLKTSTGENKSKAGLPKNTKIYHKTGSGSRTADNDAGYVRLPNGDLYYIAIMIKD +SPLSDDENSKIISDISKIVYQYf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas montana TaxID=1843236 RepID=UPI0009F9E97A +--ALAATVERLGRGFDGIVGIAVRDVQAGWYI-SFNGQGYFPQQSVSKLWVALTVFDAID +RRRMSLSDTVRIERKDLVVHQPLRAKVGPNGASVSELLLAAMTTSDNLANDSLLRTVGGP +GAVRAFLDRAQLDGIRFGPGERLLQAKYLADPIDGAQPEKVALALARLRKGDLLSPESTQ +RLLTLMASSRTGPQRMRAGSGPGWAFAHKTGTGQATGYNDIGLMTSPDGRTYALAVMIKS +TRQPIPVRQRLMANVARAVVA-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. PAMC 26605 TaxID=1112214 RepID=UPI00026CAC4C +------------------------------------------------------------ +--------------------------------SAAKVLELMIVRSDNHAADQVLAALGGP +VAVQQWLSSHNIVGIRVDRTIDQLLRGHLADSKDVATPVAMVALLHKLDSGAVLSAQSRA +FLFELMRRCETGTRRIRAMLPAGTPVEDKTGTLD-GVTNDVGFITMPDGHRVAVAVFARG +GR----DRQPVIAAAARVIYDRf +>[subseq from] Serine hydrolase n=1 Tax=Legionella sp. TaxID=459 RepID=A0A522FDW4_9GAMM +-kDLLRKISSIEKNSKVIIGVSAILIEKNKMI-THNGTKRFFMASTIKLPIAIAFLHRVD +EKKDSLNRSMTLDFKNSVPGSGSLYHTFERRVSMQRILKLMMIESDNSASDALLHAAKGP +VYVTKRMGEIGFKNVIINRSILQILMRFEKDIRDTITPNDMALLLVKLFKGQILSEESTN +LLIHIMEQCRTGRHRIKGLLPHYVKVAHKTGTWGYRFASDVGIITLPNKGHIAIAIYVKS +QSASDYPRNRAIALTSRAIYDHf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium japonicum BiD32 TaxID=1301087 RepID=N1MM32_9SPHN +-----SVVRNLGQSFRGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD +RGKLRLTDTTTITRNDLTLHQPSAAMLKDGGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKQGDMLSATSSR +LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTVSIPERWALMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=2 Tax=Microcystis TaxID=1125 RepID=A0A552AL94_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKAADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium GWC2_61_19 TaxID=1797932 RepID=A0A1F9SQN2_9BACT +-----GGLEKVSDAYRGRVGIYIKDLHTGKVW-EYNADRLFPSASLVKVPIMVSVLDKIK +LGTITLDTQIRLTRRERVGGSGSLKWVRDGTLSVMEIIYKMITESDNTATRMLIDYV-GM +DYLEDNFKRLGLVETNICQEGMSLTSG-RLKKDNYTTAREMAGLMEKIYDGEMVNREASE +FMLDVLKHNKS-RSRLRRGLPLGWEIGHKTGLLRR-SCHDVGIVFSPRGD-FVLAVLTTE +VP-DYTSAKNFITKVAKLTYAYy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Odoribacter sp. AF21-41 TaxID=2293111 RepID=A0A373UK51_9BACT +-kELEEQLRKVIANKKAQIGIAVI-INSKDTI-TINNDARYPMMSVFKLHQALAVADYCE +KKGLSFDTPIYIRKADLKTYSPLRDLYPDGELPIKELLEYTLHLSDNNACDILFQQTGGT +EATDHYIRSLGMRHFAIKATEDEMHQDKNKCYQNWSTPLETARIIELLLNVRLFDDEYQG +FIKTTMMSCETGKDRLARPLQNKAIIGHKTGTGDRNGMNDVGFVYLPDGQSYTIAVFIKD +SEESEAATARIIADISKTVYRH- +>[subseq from] Uncharacterized protein n=1 Tax=Oscillatoriales cyanobacterium CG2_30_40_61 TaxID=1805291 RepID=A0A1J5GY69_9CYAN +---LKTAILGLAKDSKLKPGVFLVDLDTGNYV-DVQGQEAVPAASTIKVPILVSFFQAVD +EGRVRLDEVLTMEEKHIAKGSGELQKPVGSKFTALETANLMITNSDNTATNMLIDRLGGI +ESLNQQFASWQLKQTQMHNLLPDLEGT------NKTSAKDLVNLMADINQGKLVSLKSRD +FMLRIMQETRN-RSLLPSGLGEGAFIAHKTGNIDS-VCGDIGLIDMPNGKRYLVGVLVQR +EA-DDPQANELIRQISSTIYQYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. TaxID=1908224 RepID=A0A2G2D3V4_9SPHN +--ALVREIQELWRAFPGKTGIAVKRIDGAWEF-GFRLDEYFPQQSVSKLWVAMTMLDKID +QGKASLSDPIRIGKEDLTLHQPMAVEVERNGKTVYTLLEMALASSDNTANDALLRHAGGP +EAVRRFIDKNSLGKIRFGPGERLLQSAYLADPVDGASPLAIAGALDKLARGELLSDNSTK +LLQSILKRTRSGPNRLKAGVPAGWEFLHKTGTGQSTGYNDVGIMTAPDGTRYAVVVMLGD +TTASIPARMRLMQSVTRAVGR-- +>[subseq from] Uncharacterized protein n=2 Tax=Microcystis aeruginosa TaxID=1126 RepID=L7EBB6_MICAE +--SLNQKLQALTVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLKGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Merismopedia glauca CCAP 1448/3 TaxID=1296344 RepID=A0A2T1BZC0_9CYAN +---LETQIKTLAAKYQLYPEVFLVDLDSGNYV-NLAGDTAISAASTIKVPVLVALLQDVD +AGKVRLNEELTLTSKVIGSGSGAIQQKIGSKFTVLEVATKMIVISDNTATNMIIERLGGQ +EKLNSRFQSWGLTTTAIKNPLPDLEGT------NTTSPKDLVEVMAMVNRGELVSMRSRD +RMLGIMRQTVT-NTLLPQGLGKGSTIAHKTGDIGS-VVGDVGLIDMPSGKRYLAAVLVKR +PH-NNPKAQELIRQISRATYNHf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=unclassified Apibacter TaxID=2630820 RepID=UPI00132AD745 +-qSLEKKIHSITKNKKATVGVAVI-FDGKDTL-TVNNDMEYPAMSVFKFHQALALLDYMN +KNLLSLESNIYLKKSDIKKYSPLAKEHPEGNIPIGDLLNYTVSKSDNNASDALYYYMNGT +KMTDLYLRTLGSKNFSIQATEEEMSKDFNNQYINWTTPLEAARLLDIFINKDIFCKNYKD +FLFQALTESETGSDKLKALLPKKVLIGHKSGSSSRNADNDIGFVYLPNGKQYSIAVFIKD +SKEDDKTNARMIADISQVVYNFy +>[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa Ma_SC_T_19800800_S464 TaxID=2486257 RepID=A0A552E248_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFSAASTIKIPILVAFFEDVD +AGKIRLDEPLVASKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc sp. UIC 10630 TaxID=2100146 RepID=UPI0014241406 +-kALEPQIKALMNRYSLKTGMFFLDLDTGDYL-DVGGDRVFPAASTIKLPIFIAFFQDLD +AGKVTLQENLTMRRDLVTNGSGTMQERVGKKYTALETITKMITISDNTATNMVIDRLGGA +TKLNQRFRNWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR +PYKD-TRGRDFIRQVSQLVYDY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium faniae TaxID=570446 RepID=A0A1G4T6G1_9SPHN +--RLLAQFESFAALTDGTVGIAVQDLSTGEEQ-SLNGDMLFPMASTYKVAVAGKILSMAD +AGVLGLQDQVPLDPA-----------QPARTRSIHDLIDLMLTHSDNDATDALVARAGGP +AVIDDWVGALGVKGLRVDSNTAHLLYAFTRDPRDTSTPRAMNALLAAIRLGQALKPASTA +YLLEMMERCHTGKARLKAMLPPGARIAHKTGSLN-GYGGDVGIVTLPDGRMFAISVFVMK +DYKGRTTRDSIMAHAARAAYDYf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Y57 TaxID=334801 RepID=UPI00063F5BFD +---LDGAIERLGRRFPGDVGLAVRDIQTGWTS-HHRGLDYFPQQSVSKLWVSLAALDQVD +GGTLDLSRPLTVRAKDLTLHQPIRALALRPGTTGEDLMIRALTQSDNSANDRLLKEIGGP +DAVRAALRGKAIAGIRFGPGEPRLQAQYLANPIDGATPIAMVDTLARLRRGELLSPASTA +KMTGIMEETRTGALRLKAGLRPGWRLAHKTGTGQQAGYNDVGILTSPDGRSYAVAVMIGR +TSRPLAERMKLMQSVVAATI--- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. 66-54 TaxID=1895845 RepID=A0A1M3PTT3_9SPHN +----VSIIETLGRNFNGSVGIAVQRVDAGWTI-AHNGNKLFPQQSVSKLWVAMTMLDAVD +RGKITLDTPVMIRPADLTLHQPIAAMVKGSGTSLRDLFYRAMTQSDNTANDSVLRTVGGP +DAVRGYLARFGPDTIRFGPGERLLQSAYLANPIDGASPLAIVHALAKLKKGDMLSPASTQ +LLLSTMSEAKTGPQRIKAGVPAGWSYLHKTGTGQSTGYNDVGIMTAPDGTSYAIAVMIGE +TTLAIPQRWELMQSVARSVA--- +>[subseq from] Beta-lactamase n=1 Tax=Calothrix sp. PCC 7507 TaxID=99598 RepID=K9PGH4_9CYAN +---LEPQIKTLMAKYSLQTGMFFLDLETGNYL-DIGGDRVFPAASTIKLPILIAFFQDLD +AGKVRLDEQLTMRSDLVTNGSGIMQERVGKKYTALETVNKMITISDNTATNMIIDRLGGA +AKLNQRFRGWGLKDTVIRRLLADLRGT------NTTSSQDLARVLALVVNNKLVSPQSRE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-IIGDAGFITMPNGKHYLAAIFVKR +PYRD-SRGRDFIRQVSQLVYNY- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. HI0063 TaxID=1822240 RepID=A0A165R5D5_9SPHN +--AFEQELEEIAASLDGTVGVAVTDVETGRSY-AIRGDDWFPQQSVSKLWVALTALDEVD +EGRLELDEAVAIGPKDLTLHQPIRDLVQARGTDYADLMQRALTGSDNTANDRILRRVGGA +EAVEDFLAAKKITGVRFGADERTKQSGYLADPIDGATPVGITEALARLARGELLSPSSTA +LILATLQNTRSGPQRLKGGVPPGWSIGHKTGTGQQSGYNDIGILTSPEGHRYTLAVLIAR +TREPTLARMRMMQEVTRATAQ-- +>[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A2D7ZJV9_9CAUL +---LASQIAALGAAFDGRAGIAVRDLEGGWTA-THDGEALYPQQSVSKLWVAVSVLDAVD +RGVLSLDDPVLVRREDLSIHQPIRDHVGRNGTTVGELLASATTRSDNAANDVLMRLVGGP +DHVRAVISARELGAISLADEERYFQTAYLEAPPDGASPVAMVEALDRLAAGELLSSTSTA +HLLDLMAQSRTGPERLAGGLVEGWSLAHKTGTGQATGYNDVGLLTAPDGRTYAVAVFIAD +TTRSVPERQALMQAVTRAVIAQ- +>[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc sp. PA-18-2419 TaxID=2575443 RepID=UPI001107B05F +-kALEPEVKALMSRYSLKTGMFFLDLDTGDYL-DIGGDRVFPAASTIKLPILIAFFQDLD +AGKVTLEEKLTMRRDLVTNGSGTMQERVGNKYTALETISKMITISDNTATNMIIDRLGGA +AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNNKLVSLQSRE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPSGKRYLAAIFVTR +PYKD-SRGRDFIRQVSRLVYDY- +>[subseq from] Beta-lactamase n=1 Tax=Microcystis panniformis FACHB-1757 TaxID=1638788 RepID=A0A0K1S6K4_9CHRO +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFREDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVASKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Uncharacterized protein n=3 Tax=Microcystis aeruginosa TaxID=1126 RepID=L8NMA8_MICAE +--SLNQKLQALTVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus choshinensis TaxID=54911 RepID=A0A0Q3SQG0_BRECH +--SLQEKLEAVLSESSATFGVVVKHLETQEEA-QINSNDYFQMASTFKVPILATLFRDVS +EGRLSLEQRIRLTEDDLVPGSGVLQEFLPGAVAVKDLAMLMIIVSDNLGTDKVLELV-GT +ERVEAFMKELGLAHISIRNSCWELLSFQPIPENNVATPADMGKLLELIATGQLVSQEACD +SILDIMKRQQL-RNRIPYLLPDKTIIACKSGTIGS-VVNDVGIVYLPEGGAFTIAAFSHG +NH-STKEGERMIARLTLTAYEHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V572_9BACT +------------------------------------------------VMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVAAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIRAGLPKSWVV---------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas paucimobilis TaxID=13689 RepID=A0A031JGZ0_SPHPI +-----SVIRNLGQSFNGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD +RGKIRLTDTTTITRKDLTLHQPTAALVGSSGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRGFLARRTIKDIRFGPGERLLQSNYLANPPDGAAPSSIVKALAKLKEGEMLSPASSQ +LLMSIMSQAKTGPQRIKGGVPAGWKYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS +TTEPIPVRWQLMQAVAKAVAA-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas hengshuiensis TaxID=1609977 RepID=UPI0005C3F8E8 +--SLVNQLDGLIRNFDGVAGIAVTSVESGWIA-TANAQRRMPQQSVSKLWVSMTVLDAVD +RGKIRLDDPLTITKSDFTLHQPVASLVKGDTATVGEIVRRAMQMSDNTCNDKLLRLVGGP +QAVRDFIARKGLGAIRFGPGEKLLQASYVKDPPDGAAPEAIASALGRLKRGELLSPTSTD +WLLRTMAGAKTGKARVRGAVPAGWDYAHKTGTGQTAGFNDVGILTAPDGRSYALAVMIGD +TPRPVRERQLLMQAVASAIVA-- +>[subseq from] Penicillin-binding protein transpeptidase n=2 Tax=Crinalium TaxID=241421 RepID=K9VW32_9CYAN +----KPQLEALATANKLQAGVFVLDLDTGAYL-DYNSSSTFSAASTIKVPVLVAFFQDVD +AGKVSLDEMLTMEPEMIAKGSGDMQYQKAGKFTALETATKMIAISDNTATNMLITRLGGA +EALNQRFRSWGLVATTINKPLPDLEGN------NSTSPQELANVMVMVNEGRLVSVRSRD +RILDIMRQTVT-KTLLPPGLGKGATIAHKTGDIGS-ILADVGLIDMPIGKRYVASVMVQR +PHND-VAARKLIQQISRLTYQYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. HKS19 TaxID=1813879 RepID=A0A5B8LMD6_9SPHN +------LVQMLTRDFGGKVGIAVKSLDEDWTV-ESNGDIKLPQQSVSKLWVAMTVLDARD +AGKLSLDDPITVKKEDLTLNQPIAALVKDAGTTVGELLQRAMTQSDNTANDRLLQYVGGP +TVVRAFLAKKAIADIRFGPGERALQSRYIADPPDGAAPRAIATALARLKRGELLSPNSTQ +YLIGTMESSRTGKLRMRGAVPEGWTFGHKTGTGQTAGYNDVGFLVSPTGKTFTIAVMIGD +TNKTIPERQALMQAVVLGVVT-- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. HI0028 TaxID=1822227 RepID=A0A176E1N6_9SPHN +--ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD +AGRLDLGEMVRIRPGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP +AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS +LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR +TREPTPVRMEMMQEVVRAVVRY- +>[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa KW TaxID=1960155 RepID=A0A1V4BL59_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVMASGSGDMQYGVNKTYTALETASKMNVISDNTATNMLIKRMGGK +EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc carneum TaxID=374162 RepID=UPI000BBBA474 +-kALEPQIKALMSRYSLTTGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFFQDLD +AGKVRLDEKLTMRGDLVTNGSGDMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA +AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNNKLVSPSSKE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKHYLAAIFVKR +PYKD-SRGRDFIRQVSQLVYNY- +>[subseq from] Penicillin-binding protein, transpeptidase n=1 Tax=Planktothrix agardhii TaxID=1160 RepID=A0A1J1JGN3_PLAAG +---LKTAILGLAKDLKLKPGVFLVDLDTGNYV-DIQGQEAVPAASTIKLPILVSFFQAVD +EGRIRLDEVLTMEEKHVAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI +ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINRGKLVSLKSRD +FMLRIMQQTRN-RSLLPRGLGDGAFIAHKTGNIDS-VSGDVGLIDMPNGKRYLVGVLVQR +EA-DDPQANELIRKISSTIYQYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=U3N7T6_KLEPN +------------------------------------------LCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAG----------------------------------------- +----------------------- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Microcystis aeruginosa NIES-2520 TaxID=2303982 RepID=A0A5A5REI9_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVMASGSGIQYLGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Nostoc carneum NIES-2107 TaxID=1973483 RepID=A0A1Z4HKW3_9NOSO +-kALEPQIKALMSRYSLTTGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFFQDLD +AGKVRLDEKLTMRGDLVTNGSGDMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA +AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNNKLVSPSSKE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKHYLAAIFVKR +PYKD-SRGRDFIRQVSQLVYNY- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter citreus TaxID=225971 RepID=UPI001321FE58 +--ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD +AGRLDLGEMVRIRPGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP +AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS +LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR +TREPTPVRMEMMQEVVRAVVRY- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas histidinilytica TaxID=439228 RepID=A0A1T5GGI9_9SPHN +---LDAAIDRLGHRFPGDVGIAVRDVQTGWTS-HHRGLDYFPQQSVSKLWVSLTALDQVD +SGRLDLSRALTVTARDLTLHQPIRALALRPGTTGDDLMVRALTQSDNSANDRLLHQVGGP +DAVRATLRGKAIAGIRFGPGEPRLQAEYLANPVDGATPIAMVDTLARLRRGDLLSPASTA +KMTAIMEETRTGALRLKAGLKPGWRLAHKTGTGQQAGYNDVGILTSPEGRSYAVAVMIGR +TNRPLAERMKLMRSVVAATI--- +>[subseq from] Serine hydrolase n=2 Tax=Microcystis TaxID=1125 RepID=A0A551Z0E9_9CHRO +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +EALNRRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. C8-2 TaxID=2492837 RepID=A0A5B9YLE4_9SPHN +---LDAAIDRLGHRFPGDVGIAVRDVQTGWTS-HHRGLDYFPQQSVSKLWVSLTALDQVD +SGRLDLSRALTVTARDLTLHQPIRTLALRPGTTGDDLMVRALTQSDNSANDRLLHQVGGP +DAVRATLRGKAIAGIRFGPGEPRLQAEYLANPVDGATPIAMVDTLARLRRGDLLSPASTA +KMTAIMEETRTGALRLKAGLKPGWRLAHKTGTGQQAGYNDVGILTSPEGRSYAVAVMIGR +TNRPLAERMKLMRSVVAATI--- +>[subseq from] serine hydrolase n=1 Tax=Xenococcus sp. PCC 7305 TaxID=102125 RepID=UPI0011817DEA +--KLKDKLSSLTANYQLEAGVYIVDLDNKNYV-NFNGSQAYSAASTIKIPVLVAFFEDVD +AGKIRLDEKLVVTKEVIGGGSGYMQKEIGTKYSALHTATDMIRVSDNTATNMLIQRLGGM +EVLNQRFAEWGLNNTAIRNPLPDLTGT------NTTSPVDLGNLLIKINRGDLISLRSRD +RLLAIMRTTKT-RTLLPQGIEKDAVIAHKTGDIRS-SLGDAGIVDMPNGKRYIVSVLVKR +PAN-DPQAKILIQKISQTTYQH- +>[subseq from] Serine hydrolase n=1 Tax=Microcystis sp. M_QC_C_20170808_M9Col TaxID=2486217 RepID=A0A551YUP1_9CHRO +--SLNRKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDEPLVATKDVMASGSGDMQYLGANKYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus nitrificans TaxID=651560 RepID=A0A3M8D553_9BACL +--SLQKKLESVLSETSATFGVTVEHLDTKEEA-RINSDQYFQMASTFKVPILATLFRDVV +EGRLSLATRIRLTEDDLVSGSGVLKEFLPGAVAVKDLATLMIIVSDNLGTDKVLELV-GI +ERVDAFMKELGLAHISIQNSCWDLLSFQPTLENNVSTPDDMCKLLALIASGELVSQEACD +GILDVMKRQQL-RNRIPYLLPDKTIIACKSGTIGS-VVNDVGIVYLPEGGAFAIAAFSHG +N-ESMKAGERIIAQLTRTAYDHf +>[subseq from] class A beta-lactamase n=1 Tax=Parabacteroides johnsonii TaxID=387661 RepID=UPI0011DD6B14 +------DIKEVIQEKKATVGVAILY--QDKIF-TLSDNQQYPLMSLFKFHVTVAALKKMD +REHIPLDSTVCITREQMHEYSPLRNKYPNQGISLRDIITYTITYSDNNTCDWLIDFAGGI +KKVGTFIKSLGIEKLNLTETEHSMHENIMNSYNNWSSPLSVVQLIKKIYTDEILSATSFA +FLEETMLNCSSGENKLKAGLPPNVKIGHKTGHSDRTSETDAGVIYLPDGERCYIAVLIKN +SLESDETNARIMADITRVIYH-- +>[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc sp. UIC 10630 TaxID=2100146 RepID=UPI0013D0D36A +-kALEPQIKALMNRYSLKTGMFFLDLDTGDYL-DVGGDRVFPAASTIKLPIFIAFFQDLD +AGKVTLQENLTMRRDLVTNGSGTMQERVGKKYTALETITKMITISDNTATNMVIDRLGGA +TKLNQRFRNWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR +PYKD-TRGRDFIRQVSQLVYDY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium japonicum BiD32 TaxID=1301087 RepID=N1MKN2_9SPHN +---LIAQFQRFASLTDGTVGIVVRDLATGETL-SLNGDTLFPMASAYKVAVAGRIFAMVD +AGALTLEERLA---------------SPAGPVPVATLLDLMLTRSDNGATDLLVARAGGP +AAVHHWVAGLGIRGLRVDSNTADLLWAFAQDPRDTATPTAMTDLVAAIRTGKALSGRSTV +ALLSIMERCRTGKARLPGMLPPGTLVAHKTGSLN-GTGNDTGVITLPDGRLFAITVFVMQ +DHKGQATRDRIMAEAARATYDYf +>[subseq from] Beta-lactamase n=1 Tax=Microcystis sp. 0824 TaxID=1502726 RepID=A0A2L2XMR6_9CHRO +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDEPLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKAADIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] class A beta-lactamase n=1 Tax=Bacteroides plebeius TaxID=310297 RepID=UPI000E4EF7F5 +-qELYTNIHQFISQQKAEVGVAIIA-DGKDTV-TVENNRRYPLMSVFKLHQALAVGNYCK +RHQLSFDTLLTVDSTDLQPYSPLRDRAPHGGFSLKQLMEYTLHLSDNNACDILFKFTGGP +AMTDRYIRSLGVNDFSIQYTEDDMHRNLNLGYENWSSPLATAEVIEALLTRTLFDKPHQE +FIKEALITCQTGTSRIVHPLQKQVTVGHKTGTGDRNAINDAGFVQFPNGHRYTLVVFVKD +SQESMEDTEAIIAQISEMVYQAf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium 28-55-16 TaxID=1970589 RepID=A0A258RNR7_9SPHN +---LENLLQEQWQLFPGRTGVAVMRLDGGEWItGQRMTELFPQQSVSKTWVALTILDLVD +QGKVSLDQKVRITRDDLAVHQPIRDRVIANGVTVLALLEQAIIASDNTANDSLLRTVGGP +QAVQSFLARKNLGAIRFGPGERLLQSRYLANPIDGASPEAIVRALARLARGELLSPASTK +LILGIMSRTSSGPNRMKAGVPTGWRFLHKTGTGQSTGYNDIGIMTAPDGTRYAMAIMMGS +TTASIPQRMSFMQFVSRTVATY- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A352H9A3_9SPHN +--ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD +AGRLDLGEMVRIRSGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP +AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS +LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAVAVMIAR +TREPTPVRMEMMQEVVRAVVRY- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Butyricimonas virosa TaxID=544645 RepID=A0A412X2A3_9BACT +-rELEEQLRKVIANKKAQIGIAVI-INSKDTI-TINNDARYPMMSVFKLHQALAVADYCE +KKGLSFDTPIYIRKADLKTYSPLRDLYPDGELPIKELLEYTLHLSDNNACDILFQQTGGT +QATDHYIRSLGMRHFAIKATEDEMHQDKNKCYQNWSTPLETARIIELLLNVRLFDDEYQG +FIKTTMMSCETGKDRLARPLQNKAIIGHKTGTGDRNGMNDVGFVYLPDGQSYTIAVFIKD +SEESEAATARIIADISKTVYRH- +>[subseq from] serine hydrolase n=1 Tax=Sphingobium vermicomposti TaxID=529005 RepID=UPI00142221B5 +------VVRNLGQSFQGKVGIAVRRIGSDWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD +RGKIRLTDTTTITRKDLTLHQPSAALVGTSGTTYSDLMRRAMTQSDNTANDTMLRAVGGP +EAVRAFLARRTIKDIRFGPGERLLQANYLANPPDGAAPTSIVKALAKLKEGDMLSPASTQ +LLLSTMSQAKTGPQRIKGGVPAGWKYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS +TTLPIPSRWELMQAVAKAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Luteibacter sp. 22Crub2.1 TaxID=1283288 RepID=A0A1T5DV67_9GAMM +--TLQASLQKLADQAPAKFGIIVVDLDGSASA-KVNDDRAYMLMSTFKAPVSAAVLHQVD +AGKLRLDQKVHVTPADVTAGSPSIGARAAKGVTVSELMTAAVTQSDNTAVDALLKLVGGG +QVVTAYLKDKGVEGMRIDMDERAVGHAAIVMQENTTTLDGAATFLRKLQAGELLSAASTK +RLLDMMQAQVI-PNRIRAGLPAGFSIADKTGTGASNAWNDMAIITAPNGKRAVVGAFLRD +TTSTDEQRAAWFKELGTVVSK-- +>[subseq from] Beta-lactamase (Penicillin-binding p rotein, transpeptidase) n=1 Tax=Chrysosporum ovalisporum TaxID=75695 RepID=A0A654SIN5_9CYAN +----KDAVQNLATANNLKPGVFFVDLETGGYV-DVNSSISFPAASTIKVPILIAFFQDVD +AGKVRLDEMLTMEKDMVATGSGNLQQQVGTQYSALELATLMSTTSDNTATNMLIARLGGI +QALNQRFQSWGLSATALRNPLPDLTGT------NTTSPKELGNLLAMVNQGNLVTMRSRD +LILDIMRRTER-NHLLPSGLGVEATIHHKTGDIAT-MLGDVGLIDIPTGKRYIAVVMIQR +SNN-DPGAEKLISSISRTAYEQf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8ZZ84_9BACT +-qKLEANVQEVDRHLDGVIGVAILDLATGQKY-LLHADEVMPTASSIKIAILAELYRQAQ +QGKVKLTDFYTLEQADLVGGSGISSVLTPGMLTLGDVAGLMISVSDNSATNVIIDRL-GM +ENVNALVDSLGLTHTRLRRKMMDLKAA-AEGRENVATPREMMLLLENLYRGKVLNQQMTE +NFFHLLSVHKE--SYIPRNLPEDLKVANKPGELE-GVRNDCGIVFAGKR-PYVISVMTTY +LKRE-RDGGDAITKISDAAYQMf +>[subseq from] serine hydrolase n=1 Tax=unclassified Erythrobacter TaxID=2633097 RepID=UPI000AC1E242 +--ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD +AGRLDLGEMVRIRPGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP +AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS +LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR +TREPTPVRMEMMQEVVRAVVRY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273) TaxID=392499 RepID=A5V4D9_SPHWW +--ALDAAIDRLGRHFPGDVGLAVRDVQTGWTS-HHRGLDYFPQQSVSKLWVSLTALDEVD +SGRLDLSRALTVTAKDLTLHQPIRALALRPGTTGDDLMVRALTQSDNSANDRLLHQVGGP +DAVRATLRGKAIAGIRFGPGEPRLQAEYLADPIDGATPIAMVDTLARLRRGDLLSPASTA +KMTAIMEETRTGALRLKAGLKPGWRLAHKTGTGQQAGYNDVGILTSPEGRSYAVAVMIGR +TGRPLAERMKLMQSVVAATI--- +>[subseq from] hypothetical protein n=1 Tax=Planktothrix agardhii TaxID=1160 RepID=UPI0003F9EF16 +---LKTAILGLAKDLKLKPGVFLVDLDTGNYV-DIQGQEAVPAASTIKLPILVSFFQAVD +EGRIRLDEVLTMEEKHVAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI +ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINQGKLVSLKSRD +FMLRIMQQTRN-RSLLPRGLGEGAFIAHKTGNIDS-VSGDVGLIDMPNGKRYLLGVLIER +EA-DDPQANELIRQISSTIYQYf +>[subseq from] Beta-lactamase n=1 Tax=Acidisarcina polymorpha TaxID=2211140 RepID=A0A2Z5FXW8_9BACT +---LQQRIATLAEEAKGIVSVSCSLPRTNLNC-DLNAHGHQPMQSAFKLPLGLAVLHAVE +QGQLSLDQQVRFLPSDIYKFSPLQDMYPNANVPLRQLLELSVGRSDNTATDILLRLMGGT +GPVQSYLDTLGLQGIQIRDSERSLHDDERRQYRNFAEPAAFVKLLRLLADTSPLNAEHAQ +YLLAIMTASPSGPKRLKGLLPAGTIVAHKTGTSGYEATNDVGLITLPDGRRLALAVLVTD +AHADEAAVEHTIASIAHACYD-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas astaxanthinifaciens TaxID=407019 RepID=UPI000A01D531 +--ELTRRIGTLGASFDGKVGIAVQAVEQGWQT-GWKDKELYPQQSVSKFFVALTAMDAVD +RGRLTLDGPVTLTRDDLTVNQPIAQRVLSGGTTVEALLIDAITKSDNTANDKLMRVAGGP +AAVRRFIADRKLGAIRFYEGERALQSRYISDPYDGAAPAAIVGTLARLKRGELLSPASTA +RLLTIMSDTRTGKNRLRGGLKPGWTLAHKTGTGQQAGYNDIGVLTAPDGRSYAVAVMIKR +TATPLIVRMNLMNEVVRAVIA-- +>[subseq from] Beta-lactamase n=2 Tax=Nostocales TaxID=1161 RepID=A0A0D6KGJ8_9CYAN +-kALEPQIQALMSRYSLTTGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFFQDLD +AGKVRLDEKLTMRGDLVTNGSGDMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA +AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNNKLVSPGSKE +QALDILRHTTV-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKRYLAAIFVKR +PYKD-TRGRDFIRQVSQLVYNY- +>[subseq from] Beta-lactamase n=1 Tax=Microcystis aeruginosa (strain NIES-88) TaxID=449441 RepID=A0A139GH62_MICA8 +--SLNRKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDEPLVATKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Scytonema hofmannii PCC 7110 TaxID=128403 RepID=A0A139X3L3_9CYAN +----KSAVQSLAASNNLTPGVFLIDLDNGGYV-DLNGAASFAAASTIKIPILVAFFQDVD +AQKIRLDESLTLESGMVAGGSGNMQKPVGTQFTALEVATKMMTVSDNTATNMLIARLGGI +DALNQRFQSWGLTTTAIRNILPDLGGT------NTTSPKELSTLMAMVGKGNLVSMRSRD +RILDIMRRTVR-NHLLPAGLGPGATIAHKTGNIGT-ILGDAGLVDVPTGKRYVVSVMVQR +PRND-PGAEKLITSISRVAYEQ- +>[subseq from] Serine hydrolase n=1 Tax=Microcystis novacekii Mn_MB_F_20050700_S1D TaxID=2486266 RepID=A0A552IF07_9CHRO +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFSAASTIKIPILVAFFEDVD +AGKIRLDETLVASKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=E4PYM7_STAAU +------------------------------------------------------------ +---NKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Serine hydrolase n=1 Tax=Chroococcales cyanobacterium metabat2.561 TaxID=2485785 RepID=A0A3N5IDN2_9CHRO +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFSAASTIKIPILVAFFEDVD +AGKIRLDEPLVASKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter citreus TaxID=225971 RepID=UPI0012EED6EA +--ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD +AGRLDLGEMVRIRAGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP +AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS +LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAVAVMIAR +TREPTPVRMEMMQEVVRAVVRY- +>[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD521F1 +--ALQQRLEKLATGKDARIGICALD-QAGTSV-CVRGDERFSLQSVVKLIAGAATLDAAD +HGAVNIEDPIIIRSENLSLKQPLAKIVERNGTNAGDLVRRAIIDSDSAAVDILINRLGGT +GKINSFLAGKAISGIRIDRDERHLQTAYQKDPRDTATPRAMTEFLAALMSGKLISTSSTD +RLLAIMNETSTFPDRLRAGVGNDWSVAHKTGTSPNVATNDVGILTAPDGGKVAISVFVAD +SRETPTRRATIIASAAQAVTEAy +>[subseq from] class A beta-lactamase n=1 Tax=Acidisarcina polymorpha TaxID=2211140 RepID=UPI000DEF41E2 +---LQQRIATLAEEAKGIVSVSCSLPRTNLNC-DLNAHGHQPMQSAFKLPLGLAVLHAVE +QGQLSLDQQVRFLPSDIYKFSPLQDMYPNANVPLRQLLELSVGRSDNTATDILLRLMGGT +GPVQSYLDTLGLQGIQIRDSERSLHDDERRQYRNFAEPAAFVKLLRLLADTSPLNAEHAQ +YLLAIMTASPSGPKRLKGLLPAGTIVAHKTGTSGYEATNDVGLITLPDGRRLALAVLVTD +AHADEAAVEHTIASIAHACYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Pelosinus fermentans JBW45 TaxID=1192197 RepID=I8TYI8_9FIRM +-kELQKKIEATLAAYRGRGGMVILNHSSGQHF-ALNPDMVFPAASMIKIPIMYEVMRQAA +AGRIDLEQLLIVKDELRVDGAGILKERPGISMTIRELVTLMIILSDNTATNMLIDLL-GM +SPVNQTMERLGLKSTVLRRQMMDFAAA-AAGQENETSPADIIRLLTTIYDHTDLPADYGK +LMIEILSRQQV-RDKLPFFLPEEIVIAHKTGTLP-GVEHDGGILFLPGG-PYIICIMTAD +LAAN-VEGLQLVATLGKVIYEHf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. 37zxx TaxID=1550073 RepID=UPI0009DF97FC +-----TAIDTMVENFGGKVGVAVKSIDDDWMI-SKNGDVPMPQQSVSKLWVAMTALDLVD +QGKLRLDEQLTITRADLTLHQPIAGLLKNGSATAGELMRRAMTMSDNTANDRLLRRVGGP +DAVNAFIKRKSLGAIKFGPGERLLQSNYVADPIDGAAAAAIANALARLKQGDLFSRASTA +HLVTLMESSRTGAARLRAKVPPGWRLGHKTGTGQTAGFNDVGFLTAPNGRSYTIAILIGD +TSRPVPERQQLMQKVVESVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Caulobacter mirabilis TaxID=69666 RepID=A0A2D2B0H3_9CAUL +-eRLDARLERMGRAFGGRIGIAVYNVDEGWAA-DFNGDALLPQQSVSKLWVSVATLDRVD +RGELSLDDRVLIRKEDLSLHQPIRAQVGEHGTTVRDLMRRAITQSDNAANDALIRRIGGP +WAVQVTVVAKNLGEIRFGPGEREMQTAYVENPPDGASALDIAETLGRLKGGGLLSPGSTA +FLLGLMAETSTGSSRLRASLAPGWTLQHKTGTGQATGYNDVGLLTAPDGTAYAVAVLIGA +SRRPFKDRSSLIAEVGRAVIA-- +>[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. E7m48 TaxID=1561197 RepID=UPI0006D3F342 +--DLARQLARIEAQAGGRLGVAILDTASSKPQ-GWRMHERFPMCSTFKFLLASAVLVCKD +QGKEQLGRKIVYAKEVVVANSPVSGPRAGGDMTVGELCEAAITRSDNTAANLLLDSIGGP +AALTAFARSIGDRVTRLDRNEPSLNEATQGDPRDTTTPAAMLADLRALL----------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Caulobacter sp. SLTY TaxID=2683262 RepID=UPI001412D3AD +-eQLQGRLDALARSFPGDVGVAVTRVDEGWTV-SVNGDRPLPQQSVSKLWVSMAILAAAD +RGELSLDERVTIRKEDLSLHQPIRKFVGEAGASLRSLMDGALQSSDNAANDALVRRLGGP +FAVQVAIVGKNLDGIQFGPGERAMQTAYLADPPDGATALGVVEALSRLYRGDLLSPDSTA +LLLERMGGSHTGASRLRAGLPPGWKLAHKTGTGQATGFNDVGLLIAPDGRVYAVAVLIGA +TRQPIEARQAFIASVASAVA--- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D8FIQ5_9SPHN +--ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD +AGRLDLGEMVRIRPGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP +AAVQDFLDTHGLSSIRFGTXERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS +LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR +TREPTPVRMEMMQEVVRAVVRY- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9G5I2_9BACT +-qKLEAAIQDIDRNLDGVLAVAILDLSTGQKY-LFHADEVLPTASSIKIAILAELYHQVQ +QGKLKLGDLYTLQSSDLVGGSGVAGALTPGVLTLRDVAALMISVSDNSATNVIIDRI-GM +ENVNALLDSLGLTHTRLRRKMMDVKAA-AEGRENIATPREMLLLLEDLYRGKILNKQMTD +DFFELLSIHKE--SYIPRELPEDLRIANKPGELE-GVRNDSGIVFTGNR-PFVISVMTTY +LHRE-KDGGEAIIRIATAAYQMf +>[subseq from] Uncharacterized protein n=1 Tax=Cyanobacteria bacterium UBA9273 TaxID=2055791 RepID=A0A352ABC2_9CYAN +---LKTQIQTLASQNNLQPGVFMVDLDTGAYL-DSDSQSIFPAASTIKVPILVAFFQDVD +AGKIRLDEPLTLEPEAIATGSGDLQKQPGSQYVALEVATKMIAISDNTATNMIIKKLGGA +AALNQRFQSWGLTATVIKNPLPDLEGT------NTSSPRDLANLMFMVNQGELVSLRSRD +RLLDIMQRTVN-NSLIPKGLGAGAIIAHKTGDIGS-LIADVGLVDMPTGKRYIIVAMVKR +PHND-GSGAELIRQISRAAYNYf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. HDW15A TaxID=2714942 RepID=UPI00140A2B11 +------------------------------------------------------------ +--------------------------------SARSLMEAMMIHSNNQATDLLLGNLGGP +DKLQQWLQERNVKGIRVDRNIADLLAAKRWDVRDSATPRAMVELLRRIDKGELLRPSSRA +YLLNLMARCQTGKNRMRALLPASAQVQHKTGTLNN-YTSDVGYFTLPDGRRLAVAFFARG +GS----NRPQTIAMAARTIYDGf +>[subseq from] class A beta-lactamase n=1 Tax=Undibacterium sp. YM2 TaxID=2058625 RepID=UPI001331EDAB +----QNVIESIAMDSGGRLGASLLVLETGQSL-WILPDTAAPMQGVSKLPIVMAALAAVD +KNKLKLDQKVTINKEDLIPPSALRDEHPEGNITAKELMHHAIVDNDGTASDALLRLLGGP +PAVMQYLAQLDIKDIKVLDTEKDLAKSWNMQYRNTATPKAMIKLLQTVQEGKALSPKSRE +LLLKWMTDTEVNAARIKALLPAGTAVVHKAGSSPTAAHNDVGIVTLPNGLHMAVAVFLTD +SKAPHASRDLTIAKITRVGWDAw +>[subseq from] Beta-lactamase class A n=2 Tax=Brevibacillus TaxID=55080 RepID=J2HUE3_9BACL +---WQKALEKALADAPGVFGVAAEHLETGESA-GQLDDQLFQLASAFKIPIMVTLMREVE +AGRVRLDQRVVTQKDTRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDLIIELVGGI +DKVEAHMHELGLKQIHLRHTCWQLLNSLPTLDNNVATPRDLNRLLMLIARKEILTQASCE +LMLDILRRQQF-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGLIYLPDGGTIAITVLSRG +VT-DKQAAELAIARAARAIYD-- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter citreus LAMA 915 TaxID=1306953 RepID=A0A0L1KBD5_9SPHN +--ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD +AGRLDLGEMVRIRAGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP +AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS +LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAVAVMIAR +TREPTPVRMEMMQEVVRAVVRY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V584_9BACT +------------------------------------------------VMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA +QLVTWLKGNTTGSASIQAGLPTSWVV---------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas taxi TaxID=1549858 RepID=A0A2W5AYQ9_9SPHN +--NLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD +QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDILSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TIRPMPERQRLIQAAAAAVAKY- +>[subseq from] Beta-lactamase class A n=1 Tax=Xenococcus sp. PCC 7305 TaxID=102125 RepID=L8M4S0_9CYAN +--KLKDKLSSLTANYQLEAGVYIVDLDNKNYV-NFNGSQAYSAASTIKIPVLVAFFEDVD +AGKIRLDEKLVVTKEVIGGGSGYMQKEIGTKYSALHTATDMIRVSDNTATNMLIQRLGGM +EVLNQRFAEWGLNNTAIRNPLPDLTGT------NTTSPVDLGNLLIKINRGDLISLRSRD +RLLAIMRTTKT-RTLLPQGIEKDAVIAHKTGDIRS-SLGDAGIVDMPNGKRYIVSVLVKR +PAN-DPQAKILIQKISQTTYQH- +>[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa Ma_QC_Ch_20071001_S25D TaxID=2486250 RepID=A0A552FYD6_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETFVATKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +EALNRRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Beta-lactamase class A n=1 Tax=Phormidium sp. OSCR TaxID=1666905 RepID=A0A0P8C7J8_9CYAN +--ELDDQLQELLGAYELTPGVMVLDVATGDYV-QLGEDAPFAAASTIKIPILVAFFQAVD +GGQVRLDEPLQLQESHIQGGAGSLQDEAPGLLSALEVATLMIVESDNTATNLLIDRLGGM +EALNDRFRQWGMTETVLQDWLPDLQGT------NTTTPRELAGLLAQIERGELLSMASRD +RLLRIMMLTEN-DTLLPQGLGSGAVIAHKTGNLR-GVLGDAGLVDVVNGRRYVVVALVER +PEYD-EEAVTLIRELSARVYGYf +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E8D3G6_9PLAN +-eELAGRLRPLIANHEGDVAVAIRHLETGEAF-QHDGGKVMPTASLIKFPVMVEAYRQST +TGEADLDSMIELRDEDRVPGSGILTNHFSSGLSLRDAIRLMIVYSDNTATNLVLDRI-GL +KSTADTMQTLGFLDTKIHAKVFRRDTRSSKYGLGSTTAIEAVRLYELLHKRRLITAEASD +AMLDHLLHCDD-RRKLAAMLPTGTEIAHKGGAVSR-VRCDAGIIYSPSG-PIAICVLTAN +NQGKDNAAEQLCARIAKTAYDHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A538RXA1_9BACT +------RITAIDRRLDGVLGVAILDLTSGQKF-LLHGDEIFPQASSIKIPVLAELYRQEQ +AGKARLTDPYTVREADLVPDSDILLGLTPGVLTNRDLATMMVAVSDNSATNILIDRL-GM +ENVNALLDSLGLAHTRLRRKMMDLKAA-QEGRENVSTPRDMMTLLEALHQGKVLNKALTA +DFFKVLATHKD--SALLRGLPDGVRAATKPGALE-GVRNDSGIVFAKNR-PFVLCIMTTY +LR-NEKQGEQAISDIAAAAYQHf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Microcystis aeruginosa NIES-2519 TaxID=2303981 RepID=A0A5A5RAQ0_MICAE +--SLNQKLQALVVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDEPLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKAADIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=2 Tax=unclassified Microcystis TaxID=2643300 RepID=A0A2P1UFC7_9CHRO +--SLNQKLQALVVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDEPLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKAADIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Microcystis aeruginosa NIES-2521 TaxID=2303983 RepID=A0A5A5S073_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFSAASTIKIPILVAFFEDVD +AGKIRLDEPLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +EALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSANIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2E9CHH1_9SPHN +--RLIAQFQRFASLTDGTVGIVVRDLGTGETL-SLNGDTLFPMASAYKVAVAGRIFAMVD +AGALTLEDQLA---------------SPAGPVSVATLLDLMLTRSDNDATDLLVARAGGP +TAVHQWVAGLGIRGLRVDSNTADLLYAFARDPRDTATPTAMTDLVAAIRTGKALSGRSTV +ALLSIMERCRTGKARLPGMLPPGTLVAHKTGSLN-GTGNDTGVISLPDGRLFAITVFVMQ +DHKGHATRDRIMAEAARASYDYf +>[subseq from] class A beta-lactamase n=1 Tax=Aphanizomenon flos-aquae TaxID=1176 RepID=UPI000489F8E5 +---LKNSLQTLSANADLMPGVFLLDLDNGGYV-DINSNASFAAASTIKIPILIAFFQDVD +AGKIRLDEILTLQKEMIVGGSGNMQYTPDSKYTALDVATKMITISDNTATNMLVAKLGGQ +EALNGRFRSWGLTTTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNVVGMRSRD +LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR +PNND-PRAAKLISSISSAAYEHf +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WNC4_9BACT +-rELTEQLRSLCDAVAGDIGVAVVHVESGKTV-AVAGDKKLPLYSVYKLPLAMTVLRDVE +AGKLRLDQKVKVTPADVAGTLFNTDLRSAQEKTVRELIEYAIVRSDNTSADKLLGLIGGP +PIVTQEMRTIGLANIDVVVSSREFTAH--RDKPNTGTTTDLAQLLARLQKGELLQPANFS +LLRDYMERAKTGERRLRANLPAGTQVADKTGTGDV-ATNDVGLITLPNKGHLAIAVLISG +SKLPVDKQEKTIADIAR------ +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3A0DMA7_9BACT +-qSLAERIEPLIKGHKGTVAVAIKHLSKDAAF-AYRGDEPMPTASLIKLAVMVETYRQAE +EKKVDLAKSITLAENDKVPGSGILTPHFSAGLSLRDAVRLMMVYSDNTATNLVLDQI-GL +KSTADSMEKLGFPNTKIHAKVFRRETRSKKFGLGSTTSNEMVGLLAKIHGKQVVSAAACE +AMLDHLRACDD-RTMLPALLPDGVKVAHKTGAVS-AIRTDAGVIESRAG-PIAICVLTAE +NSTDDNAAKVLGAKIARAAYDYf +>[subseq from] Beta-lactamase n=2 Tax=Gloeothece TaxID=28070 RepID=E0UHR7_GLOV7 +-----KKLMDLVPKYKLEARAFFVDMDNGNYV-DINAQAPIPAASTIKIFVLVALLEQID +AGKVRLDEQLTMTKDIVTSGSGDMQYPVGKKFTVLETATKMIIISDNTATDMLVKRLGGK +QVLNQRFREWGLTNTIINNILPDLEGT------NTTSPRDLAYILMRVNQGELLSLKSRD +RMLNIMQQTKT-RTLLPQGLDSDAIIAHKTGDIGT-VLGDAGIIDMPNGKRYIGAVMVKR +PYND-TAGRMMIQEISRTVYQH- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacteraceae bacterium TaxID=2026738 RepID=A0A2E7M559_9SPHN +--ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD +AGRLDLGEMVRIRSGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP +AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS +LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR +TREPTPVRMEMMQEVVRAVVRY- +>[subseq from] Uncharacterized protein n=2 Tax=Parabacteroides sp. An277 TaxID=1965619 RepID=A0A1Y4DGR5_9BACT +--DLGTQLRKAIEGKAATVGVAVIF-NGSELV-TVNDMYRYPMMSTFKFHQALSVVDYIN +RKEKTLATEILVKQSDLKTYSPMRDANRKGNITIGDLLKYSLIDSDNYACDILFEHIGGP +KTTDKYVRGLGIEDFSITQTEREMHESTDNVWLNWTKPSAAVLLLETFLQNPMFDKSQKL +FLERAMADANTGKDKLKAGLPNDVLLGHKTGSSDRNADNDMGFVVLPNGQYYTIAVFVMN +SQESDKTNARLIANISKIVYNYf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteriales bacterium 13_2_20CM_55_8 TaxID=1803470 RepID=A0A1Q6XCW1_9BACT +-qKLESAINDVDHSLDGVLGVTILDLTSGQKF-LLHADEVFPQASSIKIAVLAELYHQTQ +SGKLKLNDLYTVQASDLVPDSDIMGGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GM +ENVNGLMSSLGLTHTRLRRKMMDLKAA-SEGRENISTPGEMMVLLENLYRGKILNKEMTE +DFFKVLSTHKS--SFIPLDLPEGLKIANKPGELE-GVRNDSGVVFVEKR-PYVICVMTTY +LQR-ERDGEEAISRISLAAYRMf +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Elusimicrobia TaxID=1797919 RepID=A0A1F9W972_9BACT +-----SGLEKAAANWRGNVGIYIGDLHTGRNW-DYNADRLFPSASLIKVPIMAAVFDRIK +SGAITLGTQIRLTRADRVGGSGSLRWVRDGTLSVMEIIYKMITESDNTATKMLIDYV-GM +PYLKTAFKQLGLVHTNITQEGMSLSSG-RIARENYTTAREMAGLMERIYAGELVDREASE +FMLDVLKHTKS-RSRLRKGLPLGWEIGHKTGLLRK-SCHDAGIVFSPRGD-YVIVVLTSE +VP-DYASAKKFISRVASLTYTYy +>[subseq from] HGF-1 beta-lactamase n=1 Tax=Bacteroides sp. CAG:20 TaxID=1262738 RepID=R5ES05_9BACE +--TVGQKIRQAIQGKNATVGVAFSI--DGQLF-TFNDEHRYPLMSIFKLHVAIAALQKME +NECIALDSLRFIESSQIHKYSPLRELYPERNLSYADLMRYAVSQSDNNACDILIDYLGGI +DIVKDRIDKLGITNYNLTETEETMHSRISNCYNNWSTPSSTLQLLEKLYNEPILNETHTE +FLKNILIETSTGKDKIKAGLPDNIVLGHKTGSSDKIGDNDTGVIYLPNGKLCFLTIFIKD +SRESDQTNTQIIADIARIIYN-- +>[subseq from] serine hydrolase n=1 Tax=Sphingobium xenophagum TaxID=121428 RepID=UPI00039C29CF +--RLIAQFQRFASLTDGTVGIVVRDLGTGETL-SLNGDTLFPMASAYKVAVAGRIFAMVD +AGALTLEDQLA---------------SPAGPVSVATLLDLMLTRSDNDATDLLVARAGGP +TAVHQWVAGLGIRGLRVDSNTADLLYAFARDPRDTATPTAMTDLVTAIRTGKALSGRSTV +ALLSIMERCRTGKARLPGMLPPGTLVAHKTGSLN-GTGNDTGVISLPDGRLFAITVFVMQ +DHKGHETRDRIMAEAARASYDYf +>[subseq from] Penicillin-binding protein n=1 Tax=Anabaena sp. WA102 TaxID=1647413 RepID=A0A0K2LYD9_9NOST +---LKNSLQTLTTNADLMPGVFLLDLDNGGYV-DINSNASFAAASTIKIPILIAFFQDVD +AGKIRLDEILTLQKEMIVGGSGNMQYTPDSKYTALDVATKMITISDNTATNMLVAKLGGQ +EALNGRFRSWGLTTTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNVVGMRSRD +LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR +PNND-PRAAKLISSISSAAYEHf +>[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI001448637C +---LKNSLQTLTTNSDLISGVFLLDLDSGGYI-DINSNASFAAASTIKIPILIAFFQDVD +AGKIRLDEMLTMQKEMIAGGSGNMQYTPGSKYTALDVATKMITISDNTATNMLVAKLGGQ +EELNGRFRSWGLTTTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNIVSMRSRD +LMLNIMNRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR +PNND-PRAAKLISSISSAAYQHf +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A353CT26_9BACT +-----SALSKASIAYPGRVGVYLKDLRTGRTW-AYQPDCLFPAASLIKVPIMAAVFDKIA +RGELSLETRIRLTGKDRRGGSGSLKWAREGTLSVMELLYKMITESDNTAAQMIIDHA-GY +SYLEHAFRKIGLVYTNIAPEGMSLTSG-RVARENYTTPREMALLVDRIYAGAMINRESSQ +LMLDLMKHNK-GRTRLRKGLPMGWEIGHKTGLLRR-SCHDVGVVFSPRGD-YIIAVLTGE +VP-SYSSAKRFIAGMAKLTYGYy +>[subseq from] Beta-lactamase class A n=1 Tax=Rivularia sp. PCC 7116 TaxID=373994 RepID=K9RHF0_9CYAN +----KSSIQSLVAATNLTPGIFVANLDSGNYV-DINASTSFSAASTIKIPILVAFFQDVE +AGKIKLNEPLTMTKDMIAGGSGMRSKPVGSQFTALEVADKMMVISDNTATNMLIARMGGI +DALNQRFRSWGLIATSLQNPLPDIQGT------NTTSPKELAQVIAMVSKGQLVSRQGSQ +QILEIMRRNQR-RHLLPKGLGAGARIANKTGYIG-AMLGDVGLIELPSGKRYIAAVMVKR +PRND-SRAETLITSVSRSAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Barnesiella viscericola DSM 18177 TaxID=880074 RepID=W0ES43_9BACT +--KIDSEIRIISQRHDATIGVAFS-LDNRLYI--YNDSIRYPLMSVFKLHVAVAALQRME +AKGTQLDEILQIDSSQMQRYSPLLDRYPSGSISYADLLHYALALSDNNACDILIDYAGGI +EAVKACTDGASLTGYDLTETEASMHEHIPACYHNWAHPSSVVQLLQKIHDGALLNEEHTR +FMINTLIETSTGNNKIRAGLPAGITMGHKTGSSGTIADNDAAFIYLPDGRLCYLVIFVKD +SHETDSQNADLIARITRIIYN-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. PAMC 26605 TaxID=1112214 RepID=UPI00026CD65C +--ALATSVAILARQFDGRVGIAVRSIDRGWSV-DAGGEQRLPQQSVSKLWVAMTVLDYRD +RGRLRLTDPVTLYRDDITLHQPIAGLIKGDQTTVGELLQRALTMSDNTANDRLLRYVGGP +NSVRDFMQRKGLGDIRFGPGERLLQSRYVADPPDGAAPVAIAGALARLKRGDLLSPESTT +YLISTMESSHTGKQRMRGAVPPGWSFGHKTGTGQTAGYNDVGLLTAPDGSSYAIAIMIGD +TPRPIPARQALMQAVVASVVA-- +>[subseq from] serine hydrolase n=1 Tax=Microcystis aeruginosa TaxID=1126 RepID=UPI00130B3348 +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKAADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=2 Tax=Microcystis TaxID=1125 RepID=A0A552LN84_9CHRO +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKAADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Apibacter sp. B2966 TaxID=2656761 RepID=UPI00140BEB5B +-qSLEKKIHSITKNKKATVGVAVI-FDGKDTL-TVNNDMEYPAMSVFKFHQALALLDYMN +KNLLSLESNLYLKKSDIKKYSPLAKEYPEGNIPIGDLLNYTVSKSDNNASDALYYYMSGT +KMTDLYLRTLGSKNFSIQATEEEMSKDFNNQYINWTTPLEAARLLDIFINKDIFCKNYKD +FLFQAMTESETGSDKLKALLPKKVLIGHKSGSSSRNADNDIGFVYLPNGKQYSIAVFIKD +SKEDDKTNARMIADISQVVYNFy +>[subseq from] Beta-lactamase SHV-1 n=1 Tax=Raoultella planticola TaxID=575 RepID=A0A485A5N2_RAOPL +------------------------------------------------------------ +----------------------------------GELCAAAITLSDNTAANLLLTTLGGP +QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ +QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG +TPATMDERNKQIAAIGATLIRHw +>[subseq from] Serine hydrolase n=1 Tax=Sphingosinicella ginsenosidimutans TaxID=1176539 RepID=A0A5C6TWS2_9SPHN +-sALEQRITELGRGFNGIVGIAVRDVESGWTT-SWNGRRYFPQQSVSKFWVAITALQAAD +QGRLDLSQNATLTRADLTLHQPVAADIGPNGTSLDNFMFRALTTSDNTCNDMVLRHAGGP +AAVRAMLERNHIEGIRFGPGERIMQSHYVEDPVDGAMPEGIVDGLARLQRGELLSQRSTA +RLLSILAAVRTGPQRLRGGLAPGWQIAHKTGTGQQAGYNDIGILTAPDGHHYAVAVMIGR +TATPLPTRMALMQNVTRAVIAY- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium CG08_land_8_20_14_0_20_51_18 TaxID=2014309 RepID=A0A2H0ZBF6_9BACT +-nDLTSQLEEAARKYPGRVGIYLKDLSQNHEW-TYRPDRIFPSASLIKVPIMASVMRKVE +KDAINMDTELRLTHKDRRSGSGSLKWAREGTLSLLEIIYRMITESDNTATQMLLDYF-GM +NYFEEEFRNLGLAYTNITQDGMSLTSG-RVAKENYTTAREMGYLLEKIYAGELISRKASE +TMLDILKRNKS-RGRLRKGLPLGWEMGHKTGLLRT-ACHDAGIVFSPRGD-YLIVVLTSK +GP-DYRSAKNFISKIAKITAAYy +>[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc sp. ATCC 53789 TaxID=76335 RepID=UPI001431B6A4 +-kALEPQIKALMNRYSLKTGMFFLDLDTGDYL-DVGGDRVFPAASTIKLPILIAFFQDLD +AGKVTLQENLTMRRDLVTNGSGTMQERVGKKYTALETITKMITISDNTATNMIIDRLGGA +TKLNQRFHNWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVSMPNGKRYLAAIFVTR +PYKD-TRGRDFIRQVSQLVYDY- +>[subseq from] Beta-lactamase n=1 Tax=Cloacibacterium normanense TaxID=237258 RepID=A0A1E5UFT6_9FLAO +-nELKNKIEKIISTENGDFGVSIID-ENNNIV-EINGKKHYPLLSTFKFPIALTILHKVE +KRELSMQQQIFIKKEDLLEWSPFKEKHPDGNISLEEAINWMIVYSDNNLTDILLRLLGGT +ETVQKFI---DDENFVIKNNEDEMHRDWNSQFINKSTPNSFAQLLKKFSEGKILNSENTK +WLYQSMVKSETGVKRLKGKLP-NVKIAQRAGTSFTGAINNVGIMELPNNQKIYIAVFVHN +TSEEFSKGEEIIADIAKTTYEFy +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas soli TaxID=266127 RepID=UPI00083691CF +-qELVSSLDALTRNFGGIAGVSVASVDQGWLI-SSNGERKLPQQSVSKLWVTMTVLDQID +QGKLSLDTPVSISREDFTVHQPVAALVKDGQTTVAELIRRAMQMSDNTCNDKLLRLVGGP +DAVREFIARRSLGPIRFGPGERLLQAAYVADPPDGAAPLAIAGALARLKRGELLSPTSTD +WLIKTMEAARTGKARVRAAVPPGWTYAHKTGTGQTAGFNDVGILTAPDGRGYALAVMVGD +TNRPVRERQLLMQQVASAIVA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Butyricimonas sp. An62 TaxID=1965649 RepID=A0A1Y3W3I4_9BACT +-kELEEQLRKVIANKKAQIGIAVI-INSKDTI-TINNDARYPMMSVFKLHQALAVANYYE +KKGLSFDTPIYIRKTDLKTYSPLRDLYPDGELPIKELLEYTLHLSDNNACDILFQQTGGT +EATDHYIRSLGMRHFAIKATEDEMHQDKNKCYQNWSTPLETARIIELLLNVRLFDDEYQG +FIKTTMMSCETGKDRLARPLQNKAIIGHKTGTGDRNGMNDVGFVYLPDGQSYTIAVFIKD +SEESEAATARIIADISKTVYRH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0G3VS34_ECOLX +---------------------------------------------------CGAVLSRVD +AGQEQLGRRIHYSQNDLFEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLR------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=A0A380FJG6_STAGA +---------------------------------------------------------QVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. D43FB TaxID=2017595 RepID=A0A2A3MZU7_9SPHN +--TLVSAIRNLGQGFRGKVGIAVRRIDADWTV-AWNGTALFPQQSVSKFWVALTFLDAVD +RGKLRLTDTTTITKNDLTLHQPSAAMVKAGGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRSYLARRMIKDVRFGPGERLLQANYLANPPDGAAPTAIVGALAKLKQGDMLSAESTR +LLLTVMAEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVLIGS +TTVSIPERWALMQGVAKAVAA-- +>[subseq from] Serine hydrolase n=2 Tax=Nostoc sp. ATCC 53789 TaxID=76335 RepID=A0A367PY31_9NOSO +-kALEPQIKALMNRYSLKTGMFFLDLDTGDYL-DVGGDRVFPAASTIKLPILIAFFQDLD +AGKVTLQENLTMRRDLVTNGSGTMQERVGKKYTALETITKMITISDNTATNMIIDRLGGA +TKLNQRFHNWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVSMPNGKRYLAAIFVTR +PYKD-TRGRDFIRQVSQLVYDY- +>[subseq from] Beta-lactamase n=2 Tax=Nostoc punctiforme TaxID=272131 RepID=B2IVV4_NOSP7 +-kALEPQIKALMNRYSLKTGMFFLDLDTGDYL-DVGGDRVFPAASTIKLPILIAFFQDLD +AGKVTLQENLIMRRDLVTNGSGTMQERVGKKYTALETITKMITISDNTATNMIIDRLGGV +TKLNQRFRNWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR +PYKD-TRGRDFIRQVSQLVYDY- +>[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. B2 TaxID=2583228 RepID=UPI0011A6ED31 +--RLIAQFQRFASLTDGTVGIVVRDLGTGETL-SLNGDTLFPMASAYKVAVAGRIFAMID +AGALTLEDQLA---------------SPAGPVSVATLLDLMLTRSDNDATDLLVARAGGP +TAVHQWVAGLGIRGLRVDSNTADLLYAFARDPRDTATPTAMTDLVAAIRTGKALSGRSTV +ALLSIMERCRTGKARLPGMLPPGTLVAHKTGSLN-GTGNDTGIISLPDGRLFAITVFVMQ +DHKGHETRDRIMAEAARASYDYf +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A520VJE3_9SPHN +--ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD +AGRLDLGEMVRIRPDDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP +AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS +LVLGTLARTHSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAVAVMIAR +TREPTPVRMEMMQEVVRAVVRY- +>[subseq from] class A beta-lactamase n=1 Tax=Luteibacter sp. 9133 TaxID=1500891 RepID=UPI000689CEE4 +--TLQASLQKLADQAPAKFGIIVVDLDGSASA-KVNDDRAYMLMSTFKAPVSAAVLHQVD +AGKLRLDQKVHVTPADVTAGSPSIGARAAKGVTVSELMTAAVTQSDNTAVDALLKLVGGG +EVVTAYLKDKGVEGMRIDMDERAVGHAAIVMQENTTTLDGAATFLRKLQAGELLSAASTK +RLLDMMQAQVI-PNRIRAGLPAGFSIADKTGTGASNAWNDMAIITAPNGNRAVVGAFLRD +TTSTDEQRAAWFKELGTVVSK-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. 32-62-10 TaxID=1970436 RepID=A0A258G0R8_9SPHN +-----STIQTLRAQFAGNVGIAVRNIDKGWAV-TANGSTKLPQQSVSKLWVAMAVLDYRD +SGQLTLDDTVTVTREDLTLHQPIAAMVKGDGATVGELLQRALTTSDNTANDRLLRFIGGP +ETVRGFIRRKGLGSISFGPGERLLQSSYVTNPPDGAAPEAIAGALAMLKKGELLSANSTN +YLIATMESARTGKQRLSGAVPAGWRFGHKTGTGQTAGYNDVGILTAPDGQSYALAVMIGD +TPRPVAERQALMQSVVASVVAY- +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium sp. MI1205 TaxID=407020 RepID=A0A126RAN6_9SPHN +------VVRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMAVLDAVD +RGKLRLSDTTTITRKDLTLHQPSAGLVGSTGTSYSDLMRRAMMNSDNTANDTLLRSVGGP +EAVRSYLARRFIKDVRFGPGERLLQANYLASPPDGAAPSAIVHALAKLKEGDMLSPASSR +LLMSIMSEAKTGPQRIKGGVPAGWRYMHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTEPIPARWELMQAVARAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium tetanomorphum DSM 665 TaxID=1230342 RepID=A0A037Z4T8_CLOTT +--ELENLIEDIINNSKGDIAVAIKNLESNSTI-MINEKEVFPSASTIKLLIMVTAMQEVK +EGKRNLKDKIIISTEEKCGGDGILKELNKDHFTLIEIITLMIIISDNTATNILIDML-GM +DNINKIANELKLNNTRLQRKMMDSE-AVKMGKENLTTALDMCTILEMLYKGEIVDKEYSN +IMIEILKKQQV-NGRLTLYLPDDLVVAHKTGDLDK-LEHDVGIVYYPYCN-YIICVLTKN +LY-TNKEGREIIGKISYEVYKSf +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingobium TaxID=165695 RepID=A0A560WSK9_9SPHN +--RLIAQFQRFASLTDGTVGIVVRDLGTGETL-SLNGDTLFPMASAYKVAVAGRIFAMVD +AGALTLEDQLA---------------SPAGPVSVATLLDLMLTRSDNDATDLLVARAGGP +TAVHQWVAGLGIRGLRVDSNTADLLYAFARDPRDTATPTAMTDLVAAIRTGKVLSGRSTV +ALLSIMERCRTGKARLPGMLPPGTLIAHKTGSLN-GTGNDTGVISLPDGRLFAITVFVMQ +DHKGHETRDRIMAEAARASYDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V579_9BACT +------------------------------------------------VMAAAAVLKKSE +SGPSLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVAAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVV---------------------------------- +----------------------- +>[subseq from] CTX-M family class A extended-spectrum beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6D1LVG4_ECOLX +----------------------------------YRADESFAMCRTSKVMAAADVLKQSE +TQKKVLSQKVEIKSSDLINYNPITEKDVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFDRAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA +QLVTWLKGNTTGAASIQAGL---------------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Sphingorhabdus sp. IMCC26285 TaxID=2509718 RepID=UPI001366125C +---LENLIQEQWKQFPGKTGVAILRIDGGEWViGRRLDELFPQQSVSKTWVALTILDLVD +QGKLRLDQKVRITADDIAVHQPIRERVLAKGESVQSLLEQSITASDNTANDSLLRTAGGP +QVVRSFIARKKLGAIRFGPGERVMQSRYLADPVDGASPVAIVRALGKLARGELLSPTSTR +LLLDIMSRTSSGPNRLKAGVPVGWKFVHKTGTGQSTGYNDIGIMTAPDGTRYAMAVMIGS +TTASIPERMAFMQFVSRTVATY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingorhabdus soli TaxID=2601267 RepID=A0A5C6ULE0_9SPHN +--ALTERIDQLWASFPGKTGIAVRRIDGDWSY-AKRGDEYFPQQSVSKLWVTMTVLDAID +NGRLSLSTPVDIGPENLTVHQPIAARVAREGETVGSLIEQAITHSDNTANDSLLRTAGGP +DVVRGFIAKNGLGPIRFGPGERLLQASYVADPVDGAQPSAVVAALAKLARGELLSAQSTK +LLTETLSRTHSGPQRLKGGVPAGWQIGHKTGTGQSTGYNDIGILTAPDGTRYAIAVMLAE +TTASIPERMRLMQNVVRAVVDT- +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter aquaemixtae TaxID=1958940 RepID=UPI00135F4723 +----ERRIAMAADGDMGRIGVAAIDLSTGDRI-SVLGDQRFPMASTSKVAIAATFLAGVD +QGRWSLTSEYPLLIPVRSAYSTRVAPVRHGNITAQNHLELMISKSCNACTDALLKVVGGP +SAVNAFMRNAGIHDFQLTRDIATLVRVVTIDTRDSASPNAMVKLLADIYQGRLLSPQSRA +ILMDAMRGTTTGKYRMRSSLPSSANLAHKTGTLTR-TASDIGIFHTPDGRAIAIAIYVTG +QSQSRRLRDDRISTIAREVYNAf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas prati TaxID=1843237 RepID=UPI0012F6E25D +--ALAATIKRLGRGFDGIVGIAVRDVQAGWFI-SFNGSGYFPQQSVSKLWVALTVFDAID +RGRMSLSDTVRIERKDLVVHQPMRGKVGAAGASVSELLLAAMTTSDNLANDSLLRTVGGP +GAVRAFLARSQLTGIRFGPGERLLQAKYLADPIDGAQPEQVALALARLRKGDLLSPVSTQ +RLLTLMASSKTGPQRMRAGSGPGWAFAHKTGTGQATGYNDIGLMTSPDGRTYALAVMIKT +TRQPIPVRQRLMSDVARAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium UBA11370 TaxID=2055769 RepID=A0A350Y9A1_9CYAN +---LKSQIQALAAQNKLQPGIFLVDLDTGTYV-DWQGQSILPAASTIKVPILVAFFQDVD +AGKIRLDEPLTLEPDVIGTGSGELQQKLGHQYTALEVVTKMSAISDNTATNMIIKRLGGA +AVLNQRFQSWGLTATVINNPLPDLEGT------NTTTARDLGNLMGMLNQGQLLTLRSRD +RLLNIMQQTVN-NSLLPKGLGSGATIAHKTGDIGS-LVGDVGLVDMPNGKRYIIVTMVKR +PHND-GSASELIRNISRTVYNYf +>[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=A0A0K9YKH8_9BACL +--SLQQKLEDLLRETRGTFGIAVKNLQTGEEA-SINADRLFQLASVFKIPILATLYRDVE +AGKQTLEQRITITETDNVPGSTILASLDWGVLTMKDLAMLMIIVSDNVATDVLLKMI-GV +QNVDSYMKQLGLENTFINHSCWELLSFKADKRGNVSTATEMSRLVEMIANEQLLTKTSTD +GMMDILGRQQF-KNRLPQLLPSQAKVAHKTGTLPPGIVNDVGIVYMPDKGAFTIAVLSQG +NP-SVADGERMIARIARTAYDHf +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A3D2LCS1_9SPHN +--ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD +AGRLDLGEMVRIRSGDLTVHQPIRDIVRRDGADYSELVERAITQSDNTANDRILRRVGGP +AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS +LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR +TREPTPVRMEMMQEVVRAVVRY- +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomyces sp. SH-PL14 TaxID=1632864 RepID=A0A142WZA5_9PLAN +----AGVLTPLISAHEGEVAVAVKHLAKGDEF-THRPTETMPTASLIKLAILVEAYRQSE +AKTLDLAKLLDLRKEDMVPGSGILTDHFPVGLSVEGAAHLMIAFSDNTATNLVLDQF-GM +KAVNETMAGLGLPETRVHSKVFRRDTSIDPDRSGSTTARDMLTLLEKLHGGTLVSGPASE +AMRKHLAACDD-KLKFPRLLPKDVKVLHKTGSVAN-VRTDAGWIETPAG-PIALVVLTAN +NKGDTNAGDLLCAKVARAAYDHf +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X844_9BACT +-hELEQRLKTISDGSQGTVGLSVVHIESGKTV-SINGSSQLPLYSVYKLPLAVTVLKDVE +EKRLRLDQKIHITPQNVVQGTTANSALWQKPYTVEQLLEFSISRSDNTSSDKLVELVGGP +LQVTERMRSLGFQNLDIHISSGEFVKT--RQNPNTGSSDDLVQLLVQLHRGKILQPAQVN +LLRGFMQRATTGLHRLRGDLPRGTVVADKTGSGEAKVTNDVGIITLPRGGHLAMAVLVNG +SKLPDAAQEKLIADLARAAYDAy +>[subseq from] Beta-lactamase n=2 Tax=unclassified Nostoc TaxID=2593658 RepID=A0A2L2NGT9_9NOSO +---LEPQIKALMNRYNLKTGMFFLDLDTGDYL-DVGGDRVFPAASTIKLPILIAFFQDLD +AGKVTLQENLTMRGDLVTNGSGTMQERVGKKYTALETITKMITISDNTATNMIIDRLGGV +AKLNQRFRNWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR +PYKD-TRGRDFIRQVSQLVYNY- +>[subseq from] Beta-lactamase n=2 Tax=Pedobacter westerhofensis TaxID=425512 RepID=A0A521FJT7_9SPHI +heGLRNKIRAYASNGKCKVGVAIRLLETGDTL-SHGDAVLYPMQSVFKFPIAMSLLIAAD +KGEIDLNQRVHIKKEELKKVSALYDKYPDGNVPLLEVLSDMVTKSDNNACDIIMKILGGG +DRITRDIHRLGVPAFTVKVNEAQMSSEWPLQYLNVCRPSAQIQLLDILLNKPVLSNKNRD +LLLEMMHHTFVTPNRIRRFLPAGTPLAHRSGTSSTKATNDVGLITLPNGNHLAIAVFVAE +SYEEMDARELIIANIAKAAYEEf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacterium kitahiroshimense TaxID=470446 RepID=UPI00143C5528 +-qQLQERIKHIIDTTGGNIGVGVQGMDFKSGF-IINGNHEYPMMSVFKFPLAFAILDKVD +KGELKLSDKFHMPKASLDTWSPMVKDFPNQDVTLADLLTYAVSKSDNNACDFLYTKVGGP +VAVNQYLHHAGVKDISIVYTEGEMEKDWALQYKNWCKPAGAIKLLQLLYNQQLLSKTSND +FLIQIMRELPDWGKRITVLLPPTAELIHKTGASGMAAFNDIGIITLPNGQHLAIAVFVSD +FKAPQQRGINVIAAISKEIWDYy +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-F2F-G114-C0414 TaxID=2135662 RepID=A0A3M0EQR3_9SPHN +---LVNAISELHSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD +QGKLRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLTKGDILSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TIRPMPERQRLIQQAAAAVAH-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DBE3660 +------------------------------------------------------------ +-----QNQKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus panacihumi W25 TaxID=1408254 RepID=V6MBZ5_9BACL +--NLQQKLESVLSESSGTFGVAVKHMGTGEEA-QIRAEQYFQMASTFKVPILAALFRDAD +AGLVSLEQRYRLSEADLVPGSGVLKEFLPGAVALKDLATLMIIVSDNLATDKVLEII-GK +ERVEAYMRELGLTQISIKHDCWELLSFQASPENNVATPADMGRLLELIGTGKLASEQASD +GVLDIMKRQQL-RNRIPYLLPDETIIACKSGTVGH-VVNDVGIVYLSDDGAFAIAALSSG +NP-SVKEGERVIARLAQTAYEHf +>[subseq from] Class A beta-lactamase n=1 Tax=Erythrobacter sp. KY5 TaxID=2011159 RepID=A0A2Z4K3Z5_9SPHN +--RFEAMLRQIEGEADGTLGVELFDVSTGHSV-GINRDRKFGHCSSFKLSLAAMVLASDS +LGIVDAARRVMWSEDDLMFVSPFTTQRLTQGATLHELAEATQKYSDNTAANILLREYGGP +QALTAFWSGIGDNVSRLDRYEPRVNYVPVTEYRDTTTPAAMARTVAALAFGGVLPDAERA +LLRQWMIDTETGARRVRAGLHEELVGGDKTGTSIGSLYVDIGFVQPPKSGPFTFATYFRT +RTATDPSAEAALARVG------- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9GUN5_9BACT +-qKLEATIQDVDRNLDGVLAVAILDLTTGQNY-LFHADEVLPTASSIKIAVLAELYHQAQ +QGKLKLGDLYTLESSDLVGGSGVAGALTAGVLTLRDVAALMISVSDNSATNIIIDRI-GM +ENVNALLNSLGLTHTRLRRKMMDLKAATEG-RENIATPREMMLLLEELYRGKVLNKQFTE +DYFNLLSIHKE--SYIPRELPEDLRVANKPGELE-GVRNDSGIVFLGKR-PYVISVMTTY +LRRE-HDGGKAIIRISNAAYQMf +>[subseq from] Uncharacterized protein n=2 Tax=Bacteroides TaxID=816 RepID=R6CIK0_9BACE +---LESKIKKSIENVPAQVGVAII-INGKDTI-TVNNECHYPLMSVMKYPQALAVLHYLH +QHNQPLSTKIFIPKEALLDYSPLRDKYPEGNMPIAQLLDYTIQKSDNNACDILFNYTGGV +SYTDSYIRSLGINNFSISKTEDDMHEDLAACYENWSTPLEIASLTDMLFSKELFPTEYQN +FLKETMLNCQTGTNRLPAPLDTTARIGHKTGTSDRNGINDVGFILLPDGKRYTIAVLVKD +STESMADTEKIIANISGIVYHH- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Leaf357 TaxID=1736350 RepID=A0A0Q5R9M3_9SPHN +------------------------------------------------------------ +---------------------------------AAKVLELMIVRSDNRAADQVLDSVGGP +AALQQWLSTQKITGIRADRTIAQLLRGHLADSKDVATPVAMVTLLQKLDSGTVLTAQSRT +FLFGLMSRCATGTRRIRALLPAGTPVEDKTGTLD-GVTNDVGFITMPDGRRVAVAVFARG +GR----DHQPVIAQVSRAIYDRf +>[subseq from] Beta-lactamase n=1 Tax=Calothrix parasitica NIES-267 TaxID=1973488 RepID=A0A1Z4LLD8_9CYAN +--------QSLVAASNLTPGIFIADLDTGNYV-DINGNNSIASASTIKLPILVAFFQDLE +AGRIELNEPLKMTKEMIAGGSGNMRKPVGSEFTALEVADKMMVISDNTATNMLIARLGGM +EALNQRFRSWGLTATTLNNKLPDIQGT------NTTSPKELAQVMGMVTKGQLVSSTMSQ +RIIEIMARNQR-RHLLPKGLGAGARIANKTGFIG-AMLGDVGLIELPTGKRYVVAVMVKR +PRND-PRAETLIPSISRSAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas hengshuiensis TaxID=1609977 RepID=A0A2W5B057_9SPHN +--ALVAAINALGGGFQGKVSIAVRSIDDGWVV-GHAMDQRMPQQSVSKLWVALTVMNAID +EGKLALTTPVTITRGDLTLHQPIAYLMKNGATTVGDLLRRALMMSDNTANDKLLNLAGGP +VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLHHGMLLTPQSTN +WLLDTMSHTRTGRARIRAALPTGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD +TARPVPERQQLIQTVVSSIV--- +>[subseq from] Putative beta-lactamase protein n=1 Tax=Microcystis viridis NIES-102 TaxID=213615 RepID=A0A3G9JQ63_MICVR +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDEPLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NSTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSANIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium RIFCSPLOWO2_12_FULL_63_15 TaxID=1802170 RepID=A0A1G3K1E9_9SPHN +--TLVSAIRNLGQGFRGKVGIAVRRIDADWTV-AWNGTALFPQQSVSKFWVALTFLDAVD +RGKLRLTDTTTITKNDLTLHQPSAAMVKAGGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRSYLARRMIKDVRFGPGERLLQANYLANPPDGAAPTAIVGALAKLKQGDMLSAESTR +LLLTVMAEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVLIGS +TTVSIPERWALMQGVAKAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. UV9 TaxID=1851410 RepID=A0A4Q0GNJ1_9SPHN +--SLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD +QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGALLTRALTHSDNTANDRLLTRVGGP +PAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TTRPMPERQKLIQAAAAAVANY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Nostoc sp. 3335mG TaxID=2204170 RepID=A0A318B9S7_9NOSO +--------------FQGRVGIAVRSIDDGWVV-GHAMDQRMPQQSVSKLWVALTAMNAID +EGKLALTTPVRITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTLSDNTANDKLLNLVGGP +VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLHHGMLLKPQSTS +WLLDTMSHTRTGRARLRAALPAGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVLIGD +TARPVRERQQLIQTVVSAIVA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium TaxID=1978525 RepID=A0A4Q3DEW5_9SPHN +----VSSLNALTRNFGGVAGVSVASVDQGWLI-SSNGERKMPQQSVSKLWVTMTVLDQID +QGKLSLDTPLSFTSEDFTVHQPIAALVKDGQTTVGEVIRRAMQMSDNTCNDKLLRLVGGP +DAVRDFIARRGLGPIRFGPGERLLQAAYVSDPPDGAAPLAIAGALARLKRGELLSPTSTD +WLIATMEAAKTGRARVRAAVPAGWTYAHKTGTGQTAGFNDVGILTAPDGRGYALAVMVGD +TTRPVRERQLLMQQVAAAIVA-- +>[subseq from] Beta-lactamase n=1 Tax=Aequorivita sublithincola (strain DSM 14238 / LMG 21431 / ACAM 643 / 9-3) TaxID=746697 RepID=I3YUS1_AEQSU +---LQSKIETIISAKKGTIGVSIIGPKTSDNV-SINGEEMFPMLSTFKFPIALMVLHKVE +VRELSMQQQVFIKKEELLQWSPFREKYPEGNISLEEGINWMVNYSDNNITDILLRLIGGT +DQVEKFLNN---KIFIIKNNEDDMHKDWESQFINKATPSAFTELLKNFSEEKILNKENTA +WLYQAMVGSRTGVNRLKGKLP-NVEIAQRAGTSFTGAINNVGIIELPNKHKIFIAVFIHN +TSEEFEKAEEIIADIAKATYDYy +>[subseq from] serine hydrolase n=1 Tax=Clostridium lundense TaxID=319475 RepID=UPI000481B14F +--ELKEKISDIINENKGDVGVVVKNLNTDSTI-MINEEEVFPSASTIKLVIISTLMKEVS +KGIMKLDDKIVLTNKCKCGGDGILKELNDGKFTLKEIATLMIILSDNTATNILIDLL-SM +EKINEMAKELNLPNTQLRRKMMDSEAA-RMGRENVTTAKDMCHILELIYKGKVVSEEYSD +IILDILKRQQV-GGRLNLYLPEEITIAHKTGDLDK-LEHDVGIVYHQHC-NYIICVLTKN +VE-TNKDGREIIGKVSLQVYN-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. 28-62-11 TaxID=1970432 RepID=A0A258RA27_9SPHN +-----STIQSLRTQFAGNVGIAVRNIDKGWAV-TANGSTKLPQQSVSKLWVAMAVLDYRD +SGQLTLDDTVTVTREDLTLHQPIAAMVKGDGATVGELLQRALTTSDNTANDRLLRFIGGP +ETVRGFIRRKGLGSISFGPGERLLQSSYVTNPPDGAAPEAIAGALAMLKKGELLSANSTN +YLIATMESARTGKQRLSGAVPAGWRFGHKTGTGQTAGYNDVGILTAPDGQSYALAVMIGD +TPRPVAERQALMQSVVASVVAY- +>[subseq from] Uncharacterized protein n=2 Tax=Parabacteroides johnsonii TaxID=387661 RepID=K5Y3V5_9BACT +------DIKEVIQEKKATVGVAILY--QDKIF-TLSDNLQYPLMSLFKFHVTVAALKKMD +REHIPLDSTVYITREQMHEYSPLRNKYPNQGISLRDIITYTIIYSDNNTCDWLIDFAGGI +KKVDTFIKSLGIKKLNLTETEHSMHENIMNSYNNWSSPLSVVQLIKKIYTDEILSATSFA +FLEETMLNCSSGENKLKAGLPPNVKIGHKTGHSDRTSETDAGVIYLPDGERCYIAVLIKN +SLESDETNARIMADITRVIYH-- +>[subseq from] Beta-lactamase class A n=1 Tax=Parasphingorhabdus marina DSM 22363 TaxID=1123272 RepID=A0A1N6H9H5_9SPHN +--ALEREIFELWRAFPGKTGIAIKRIDQNWEI-GQRANENFPQQSVSKLWVAMTVLHKVD +KGEISLSDSIRIGPDDLTLYQPLAREVARNGKSVYTLLDRALAQSDNTANDALLRHAGGP +DAVNDFIRRSRLGEIRFGPGERLMQSDYLADPIDGATPGAIVNALDKMARGKLLSENSTR +LLQSILTRTRSGPKRLKAGVPPGWGFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLGN +TTAPVPERMQLMQSVTRAVARY- +>[subseq from] Peptidoglycan glycosyltransferase n=2 Tax=Calothrix sp. NIES-3974 TaxID=2005462 RepID=A0A1Z4NFC5_9CYAN +--TLKTAIQNLASANNLTPGVFVLDIASGAYV-DLNAGATFSAASTIKIPILIAFFQEVD +AGNIRLDETMTMKQEFIAGGSGDMQKPVGTKYTALEVANKMMTISDNTATNMLIDRLGGI +SSLNQRFQSWGLATTQIRNILPDLEGT------NSTTPKELGQLLTMLNKGNLVSMISRD +RILEIMRQTVR-DTLLPVGVGQDSKIAHKTGDIRS-MIGDAGLVDISNGQRYAIAVMVQR +PDND-PRAERLIGSISRTVYQH- +>[subseq from] Beta-lactamase n=1 Tax=Terriglobus saanensis (strain ATCC BAA-1853 / DSM 23119 / SP1PR4) TaxID=401053 RepID=E8UZF8_TERSS +--SLQSRIATIAATIPAKVSVACSLPNTPLNC-DLNPDANPPMQSVFKFPLAVAVLHRAD +EGKLFLDTPVRYLSVDIISYSPLQDKYPRGNVPLRELITLSVSKSDNTASDILLRILGGP +PVLDAYIHTLGVTGFQVRDNEKSLHATNALQYRNTFSPRAATQLLRLMADRSPLSPASTR +FLNDIMLHATSGPHRIHGDLPEGTSVAHKTGTSGTAATNDIGLITLPNGQRLAIAIFVTD +AHATPEAIEHVMAQIARAAYD-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=2 Tax=Sphingomonas jeddahensis TaxID=1915074 RepID=A0A1V2EV52_9SPHN +---LDASIQQMVREFPGVAGVAVRAVDEGWTI-QAGGRRLLPQQSVSKLWVAMTVLDQRD +SGRLKLDDPVSVTAADLTLHQPIASLVKGGQTTVGNLLFRALTQSDNSANDRLLTLVGGP +SAVRAFIERKQLGDIRFGPGERHLQAAYIDNPPDGAAPLAIADALARLARGELLSETSTR +LMVSTLEASKTGRARLKAGLAPGWTLAHKTGTGQNAGFNDVGLLTAPDGRRYAVAVMIGD +TTRPMRERQQLISAVASTV---- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. EC-HK427 TaxID=2038396 RepID=A0A5E7ZHP9_9SPHN +--ELAANIDRLGEDFGGSLGVAVVDVERDWQT-DWNGTQLLPQQSVSKLWVAFTALRQAD +TGALDLGRDVTLTRADLAVYQPIREEILAAGASVEDLITRAITQSDNTANDAVLNVIGGP +EAVRAELADAQLGDIRFGPGERAMQSRYQDDPVDGASALAIAGALARLERGHLLTRERTR +WLIDVMFATRSGPNRLRAGAPEGFTLAHKTGTGQQSGYNDVGLLYAPDGTAYAIAVMIGE +TQRPTEERMAMMQAVTRAVADY- +>[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00115AB0D5 +------------------------------------------------------------ +-----------------------------------------ATMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas sp. PP-F2F-A104-K0414 TaxID=2135661 RepID=A0A4R2TW87_9SPHN +--SLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD +QGKLRLDEPIVVRPQDLTLHQPIAMLVKGDGTTINDLLTRALTHSDNTANDRLLARVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDILSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TIRPMPERQRLIQAVAAAVANY- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' 232 TaxID=2014531 RepID=A0A235J1E2_9NOSO +-kALEPQIKALMNRYNLKTGMFFLDLDTGDYL-DVGGDRVFPAASTIKLPILIAFFQDLD +AGKVTLQENLTMRGDLVTNGSGTMQERVGKKYTALETITKMITISDNTATNMIIDRLGGV +AKLNQRFRNWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSSQSRE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR +PYKD-TRGRDFIRQVSQLVYNY- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Aminicenantes bacterium TaxID=2052149 RepID=A0A2N7QCY1_9BACT +-kQLATEIKSVVDSVDGVVGIAIKDLSSGYAF-YLNENEVFPQASSIKIAIWLEVLKQVE +EGKLKLDEFLDLKPQDKVGGGPILVFLGNPSISIRDLCVLMVVLSDNTATNLLIERV-GM +EAVNKRLRSLGLTQTKLQRKMMDLKAA-EEGRENISTPREMLSLMEKIWKGQVLSPELRQ +EFFNLLALPKD--SPLQKVVPEGVVVADKPGELE-AVRCDSGLVFLKKH-PYVIGIMTTY +LSP-QVDGNEIIKKIGALAFHYf +>[subseq from] Putative beta-lactamase n=1 Tax=Bacteroides coprocola DSM 17136 TaxID=470145 RepID=B3JEU5_9BACE +---LESKIKKSIENVPAQVGVAII-INGKDTI-TVNNECHYPLMSVMKYPQALAVLHYLH +QHNQPLSTKIFIPKEALLDYSPLRDKYPGGNMPIDQLLDYTIQKSDNNACDILFNYTGGV +LYTDSYIRSLGINNFSISKTEDDMHKDLAACYENWSTPLEIASLTDMLFSKELFPTEYQN +FLKETMLNCQTGTNRLPAPLDTTARIGHKTGTSDRNGINDVGFILLPDGKRYTIAVLVKD +SKESMADTEKIIAKISEIVYHH- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium GWA2_61_42 TaxID=1797923 RepID=A0A1F9QGL2_9BACT +--DLTAGLEKTSGAYRGRVGIYLKDLHTGKVW-EYNSDRLFPSASLIKVPIMASVFEKIK +LGAITLDTQIRLTRRGRVGGSGSLKWVRDGTLSVMEIIYKMITESDNTATKMLIDYV-GM +DYLDESFKKLGLTYTNITPEGMSLSSG-RVKKENYTTAREMAGLMERIYAGELVNREASE +FMLDVLKHTKS-RSRLRRGLPLGWEIGHKTGLLRR-SCHDVGIVFSPRGD-FLLAVLTSE +VP-DYTSAKNFIARVAKLTYAYy +>[subseq from] Genome sequencing data, contig C307 n=1 Tax=Microcystis aeruginosa PCC 9808 TaxID=1160284 RepID=I4HTW8_MICAE +--SLNQKLQVLAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. PP-CE-3G-477 TaxID=2135660 RepID=A0A2T5GQV5_9SPHN +---LERVLSMLVAERSGDYGIAALDLRDGSTV-SIRGDTPFPMASTVKLAIAGAYLADVD +QGRRTLGDMIVGRP-------------------AAKALELMIVRSDNQATDQLLAALGGP +VVIQQWLWSHKIAGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLTAQSRN +FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG +GR----DRQPVIAEVSRAIYDYf +>[subseq from] Serine hydrolase n=2 Tax=Phenylobacterium sp. HYN0004 TaxID=2201350 RepID=A0A2Z3HSX1_9CAUL +----AERLAALDPGFPRPVGIAVMDVGSGWLA-SWQGDQPFPQQSVSKLWVALTIMDQVD +ARRLDLDQPVILTDADRSVNQPVTHLIENGATTVRDLLQRALIQSDNAANDKLMALAGGP +AAVQAFLASRGMSGIRLAEDERRLQSAYVEQPFDGATPAGIVRALAALHRGELLSRTSTD +FILQTLGRVTTGPMRLRGGLPPGWRAAHKTGTGQTFGLNDVGLVTAPDGRTYAVAVLAPQ +APKGSPNRLRVFQSVSAALVEQw +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Cyanobacteria bacterium UBA11049 TaxID=2055787 RepID=A0A3D1P7F7_9CYAN +-------VQQLAAQNKLLPGVFFVDLDTGNYM-DLNGETTFSSASTIKFPVLVAFFQDVD +AKKIRLDEQLTVKQELIGGGSGDLQKPVGTKLSALSTAIKMITISDNTATNMLIDRLGGA +KALNQRFSSWGLAVTEIRNPLPDLSGT------NTTSPRDLAQLMAAVEQGNLISVKSRD +RLLDIMRHTAI-VTLLPKGLGEGATIAHKTGDIGS-MVGDVGLVDMPSGKRYVAVAMVKR +PHN-NEQAKELIRSFSRAAYQQf +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium xenophagum TaxID=121428 RepID=A0A401IY62_SPHXE +--RLIAQFQRFASLTDGTVGIVVRDLGTGETL-SLNGDTLFPMASAYKVAVAGRIFAMID +AGALTLEEQLA---------------SPAGPVSVATLLDLMLTRSDNDATDLLVARAGGP +TAVHQWVAGLGIRGLRVDSNTADLLYAFARDPRDTATPTAMTDLVAAIRTGKALSGRSTV +ALLSIMERCRTGKARLPGMLPPGTLVAHKTGSLN-GTGNDTGVISLPDGRLFAITVFVMQ +DHKGHETRDRIMAEAARASYDYf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=unclassified Apibacter TaxID=2630820 RepID=UPI00132C6BC4 +-qSLEKKIHSITKNKKATVGVAVI-FDGKDTL-TVNNDMEYPAMSVFKFHQALALLDYMN +KNLLSLESNLYLKKSDIKKYSPLAKEYPEGNIPIGDLLNYTVSKSDNNASDALYYYMSGT +KMTDLYLRTLGSKNFSIQATEEEMSKDFNNQYINWTTPLEAARLLDIFINKDIFCKNYKD +FLFQAMTESETGSDKLKALLPKKVLIGHKSGSSSRNADNDIGFVYLPNGKQYSIAVFIKD +SKEDDKTNARMIANISQVVYNFy +>[subseq from] Serine hydrolase n=2 Tax=unclassified Cyanobacteria (miscellaneous) TaxID=1983111 RepID=A0A3C0NC11_9CYAN +---LEPQVKALMARYSLKTGMFFLDLDTGNYL-DIGGDRVFPAASTIKLPILIAFFQDLD +AGKVSLDETLVMQRRLITGGSGTMQYNSAGTFSARETVTKMITISDNTATNMIIDRLGGI +TKLNQRFRSWGLKDTIIRNWLADLRGT------NTTSSKDMVRLLALLINNQLVSLSSRE +QVLDILRHTTI-KTLLPAGLGPGADIADKTGDIGF-LIGDAGVITMPNGKRYLAGIFVRR +PYKD-SRGRDFIRQVSSLVYNY- +>[subseq from] Beta-lactamase class A n=2 Tax=Oscillatoriales cyanobacterium JSC-12 TaxID=864702 RepID=K8GFU4_9CYAN +---LKTAVQGVVQQYGFTPGVFLIDLDNNNFV-DLSGSASFAAASTIKVPVLIAFFQDVD +AGKIRLDEKLTMRKDLIAPESGDMQYLPPGAFTALETATKMITISDNTATNMLIDRLGGI +QAVNQRFKSWGLSATQITNLLPDLKGT------NTTSPKELASLMVRVSQGELVSLRSRD +RLLDIMRRTVN-NSQLPQGLGEGATIAHKTGDIGT-LIGDVGLVDMPSGKRYAAAVLIKR +AFND-DRAYDLVQKISRTMYQHf +>[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR459 TaxID=1500292 RepID=UPI000648672C +--DLKKTIESIISHKKADVGVSIMGPYQKETI-QINGNKLYPMLSTVKFPIALTVLKKVE +KGELSLQQKLFIKREELLEWSPFKKEHPDGNISLEEALKWIVLYSDNNICDILMRLVGGP +EPVQQLVNS---KDCIIQNNEEDMHKDWESQFVNKITPNEAIRLLETFNNGKILNKKHHL +WLYNAMLNNTAGPKRLKGSLPEYVKVAHRTGTSFTGAINDFGIIELSGSQKIYIAVFVHD +TYEKFENAEAIIADIAKVTYEFy +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonadales TaxID=204457 RepID=A0A126RJ66_9SPHN +------VVRNLGQSFNGKVGIAVRRVGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD +RGKIRLSDSTTITKKDLTLHQPTAALVGNSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRSYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ +LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTEPIPTRWQLMQAVAKAVAA-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf357 TaxID=1736350 RepID=UPI0009EB8815 +------------------------------------------------------------ +---------------------------------AAKVLELMIVRSDNRAADQVLDSVGGP +AALQQWLSTQKITGIRADRTIAQLLRGHLADSKDVATPVAMVTLLQKLDSGTVLTAQSRT +FLFGLMSRCATGTRRIRALLPAGTPVEDKTGTLD-GVTNDVGFITMPDGRRVAVAVFARG +GR----DHQPVIAQVSRAIYDRf +>[subseq from] serine hydrolase n=1 Tax=Porphyrobacter donghaensis TaxID=267135 RepID=UPI00093EB6BE +--TFEQRIAELANPALGRIGVAAVDLATGEEV-MVLGDQLFPMASTSKIAIAATYLEMVE +QGRYTLTSEFPLLLPVRSASSAKAPVRPGQYMPAIDLIEIMITRSSNPATDALLAAVGGP +QAVNSWMARKGLAPFSLNRDIATLVRANHIDSRDAATPRAMVRLLAGLYRGEYLSDQSRQ +VILGAMSRTVTGKRRIPANMPLEARVSHKTGSLSN-TSSDIGLIECPDGRVIAVAIYVTG +QG-TKLAREERIAAIARALYDGf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A350KUF0_9SPHN +--ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD +AGRLDLGEMVRIRPGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP +AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS +LVLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR +TREPTPVRMEMMQEVVRAVVRY- +>[subseq from] serine hydrolase n=1 Tax=Microcystis aeruginosa TaxID=1126 RepID=UPI00130A9DDA +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFSAASTIKIPILVAFFEDVD +AGKIRLDEPLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +EALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-LLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus invocatus TaxID=173959 RepID=A0A3M8CKD9_9BACL +--SLQEKLEHVLSESSATFGVVVKHLGTGEEA-RVRPEQYFQMASTFKVPILATLFRDID +EGTCSLEQRFRLTEDDLVPGSGVLKEFLPGAVALRDLATLMIIVSDNLATDKILELI-GA +ERVDAYMKELGLQNISIKQSCWELLSFQPTPENNVTTPADMNQLLEWIGTGQLSSQAASD +GILDIMKRQQL-RNRIPYLLPDQTVVASKSGTVGH-VVNDVGIVYLPEEKGAFTITALSF +GHASTKEGERMIARLAQTAYEHf +>[subseq from] Putative beta-lactamase class A n=1 Tax=Sphingobium sp. ba1 TaxID=1522072 RepID=A0A087NIN7_9SPHN +--TLVSAIRNLGQGFRGKVGIAVRRIDADWTV-AWNGTALFPQQSVSKFWVALTFLDAVD +RGKLRLTDTTTITKNDLTLHQPSAAMVKAGGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRSYLARRMIKDVRFGPGERLLQANYLANPPDGAAPTAIVGALAKLKQGDMLSAESTR +LLLTVMGEAKTGPQRIKGGVPPGWAYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVLIGS +TTVSIPERWALMQGVAKAVAA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2Z4WTF0_ECOLX +------------------------------------------------------------ +-----LNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGQ---------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Microcystis aeruginosa TaxID=1126 RepID=UPI00130D1C3C +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFSAASTIKIPILVAFFEDVD +AGKIRLDEPLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-LLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Microcystis aeruginosa NIES-2549 TaxID=1641812 RepID=A0A0F6U5V0_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFSAASTIKIPILVAFFEDVD +AGKIRLDEPLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-LLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf357 TaxID=1736350 RepID=A0A0Q5RBJ1_9SPHN +--ALVANVTTLGTNFQGKVGIAVHSIDQGWTV-QSNGETRMPQQSVSKLWVAMTVLDFRD +AGRLKLDDPVTIRREDLTLHQPVAALVKGDGTTVGELLQRALTMSDNTCNDRLLQYVGGP +AAVRAFIARKNLGDIRFGPGERLLQSRYVANPPDGAAPLAIAGALAKLKQGKLLSASSTD +YLIGTMESSRTGKQRMHGAVPPGWSFGHKTGTGQTAGYNDVGVLMAPDGRSYSLAVMIGD +TPRPIPERQALMQAVVAAVVM-- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas sp. PP-CC-3A-396 TaxID=2135655 RepID=A0A4R2U6E2_9SPHN +--SLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD +QGKLRLDEPIVVRPQDLTLHQPIAMLVKGDGTTINDLLTRALTHSDNTANDRLLARVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDILSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TIRPMPERQRLIQAAAAAVAKY- +>[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa Ma_MB_S_20031200_S102 TaxID=2486254 RepID=A0A552EKF9_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFSGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK +KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V567_9BACT +------------------------------------------------VMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQQA +QLVTWMKGNTTGAASIQAGLPASWVV---------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Mn802worker TaxID=629773 RepID=UPI00035D02FB +--RLRAEVDRLIAGFPGKAGAAIRAVDDGWTV-QRGGALSMPQQSVSKLWVALTVLSQRD +AGKLRLDDPVLVTTNDLTLHQPIASLVRGEGTTVMGLLTRALTQSDNTANDRLLTLVGGP +SAVRAFIAEHQLGAIRFGPGERLLQSRYIDNPPDGAAPLAIADALARLARGDLLSETSTR +VMLDTMGASITGRARLRAALPAGWKIAHKTGTGQNAGFNDVGLLTAPDGKRYAVAVMIGD +TRAPMRERQQLIQNVAAAL---- +>[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa Ma_MB_F_20061100_S20D TaxID=2486253 RepID=A0A552EYS3_MICAE +--SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD +AGKIRLDETLVASKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK +KVLNQRFQAWGLTSTVINNPLPDLEGT------NTTSPKDLVTILGKVNQGELLSLRSRD +RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR +PHND-SNARTLIQQISRTAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Luteibacter yeojuensis TaxID=345309 RepID=A0A0F3JZ35_9GAMM +--TLQAHLQAVADQAPGTLGILVMDPATGGTV-TVNDHRPYLMMSVFKAPIAAAVLASVD +AGTLSLDKKVALTPADIVEGSAVPGEALKAGFSIDELLHAAVTQSDNTAVDALLRVLGGG +KAATAFLTGKGVQGIRIDMGERELGAAVLASQVNSATLHGAAAFLRKLQAGELVSPASTQ +KLLGLMTAQVI-PNRLRGGLPAGYQLADKTGTSGTRAFNDIGIVTAPGGGKRIVVVFLAE +ARATPEQATKWFAEIGHEVT--- +>[subseq from] serine hydrolase n=1 Tax=filamentous cyanobacterium ESFC-1 TaxID=1128427 RepID=UPI0004AF6E9A +---LKQKIEALAAQYDLEVGALLVDLDTGLYV-NIRGEESFAAASTIKLPILIAFFQAID +ANQVSLDEKLTMRPDLIAGEAGTMQQQPGTQFTALETMKKMIEISDNTATNIAIDRLGGA +TVLNQRFQDWGLQATVIQNLLPDVEGT------NTTSPKDLAELMAMMNQGEIMSSRSRD +RVLDIMQNVQT-NSLLRQGIGQEATIAHKTGNIGS-LVADAGIIDTPTGKRYLAVVMVKR +PHND-PKAIELIQEISRTAYEYf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=uncultured Bacteroides sp. TaxID=162156 RepID=A0A1C5Y5U0_9BACE +-qELYSNINHFIAQQKAEIGVAIIA-EGKDTL-TIGNNHHYPLMSVFKLHQALAVGNYCE +KHRISFDTLLTVSKTDLKRYSPLRDQHPNGGFSLKQLMQYTLHLSDNNACDILFRFMGGP +DVTDRYIRSLGIKDFSVQHTEEDMHRNLNLCYQNWSTPLATAEVIEALLTRPLFDKEHQE +FIKKSLITCQTGKSRIVRPLQKNVIVGHKTGTGDYNAINDAGFIVFPDGRRYTLVVFVKN +SQENPEHTEVIIAHISEMVYQAf +>[subseq from] serine hydrolase n=1 Tax=Luteibacter yeojuensis TaxID=345309 RepID=UPI000ACB8784 +--TLQAHLQAVADQAPGTLGILVMDPATGGTV-TVNDHRPYLMMSVFKAPIAAAVLASVD +AGTLSLDKKVALTPADIVEGSAVPGEALKAGFSIDELLHAAVTQSDNTAVDALLRVLGGG +KAATAFLTGKGVQGIRIDMGERELGAAVLASQVNSATLHGAAAFLRKLQAGELVSPASTQ +KLLGLMTAQVI-PNRLRGGLPAGYQLADKTGTSGTRAFNDIGIVTAPGGGKRIVVVFLAE +ARATPEQATKWFAEIGHEVT--- +>[subseq from] serine hydrolase n=1 Tax=unclassified Erythrobacter TaxID=2633097 RepID=UPI000ACF5E06 +haALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD +AGRLDLGEMVRIRSGDLTVHQPIRDIHRDGSADYAELVERAITQSDNTANDRILRRVGGP +AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS +LVLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAVAVMIAR +TREPTPVRMEMMQEVVRAIVR-- +>[subseq from] serine hydrolase n=1 Tax=Geitlerinema sp. PCC 7105 TaxID=102127 RepID=UPI0003483B50 +--ALKERLQQVATEYGLTPGVAIVEVATGDYV-RLSDTMSFSAASTIKVPILVAFFRAVD +AGTVRLDEVLTMEESHVAEGSGYMQYAPGTRYSVLEVASSMIIDSDNTATNMLVDRLGGA +KVLNEQFREWGLTETTIRNPLPDLEGT------NTTTPQELAKLLGQLERGELVSMRSRD +RMMRIMSQTAN-DALLPQGLGEGAFVAHKTGNLRS-VLADAGAIDLPNGKRYLMVAIVKR +PDED-DRAADLIRQMSATAYDYf +>[subseq from] Class A beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A249MSY8_9SPHN +--RLIAQFQRFASLTDGTVGIVVRDLGTGETL-SLNGDTLFPMASAYKVAVAGRIFAMID +AGALTLEEQLA---------------SPAGPVSVATLLDLMLTRSDNDATDLLVARAGGP +TAVHQWVAGLGIRGLRVDSNTADLLYAFARDPRDTATPTAMTDLVAAIRTGKALSGRSTV +ALLSIMERCRTGKARLPGMLPPGTLVAHKTGSLN-GTGNDTGVISLPDGRLFAITVFVMQ +DHKGHATRDRIMAEAARASYDYf +>[subseq from] Serine hydrolase n=2 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9EAZ5_9BACT +-qKLEAAIQDIDRNLDGVLAVAILDLSTGQKY-LFHADEVLPTASSIKIAILAELYHQVQ +QGKLKLGDLYTLQSSDLVGGSGVAGALTPGVLTLRDVAALMISVSDNSATNVIIDRI-GM +ENVNALLDSLGLTHTRLRRKMMDVKAA-AEGRENIATPREMMMLLEDLYRAKILNKQMTD +DFFELLSIHKE--SYIPRELPEDLRIANKPGELE-GVRNDSGIVFTGNR-PFVISVMTTY +LHRE-KDGGEAIIRIATAAYQMf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium TaxID=1978525 RepID=A0A4Q3ABN4_9SPHN +---LTATVDALARDFGGVVGISVRSLEWGWQV-DANGNRRMPQQSVSKLWVAMTVLDARD +KGRLTLDDPVELTREHLTLHQPIASLVVRDGTTVRELLLRAMQTSDNTANDRLLTLVGGP +QAVRAFIADRALGEIRFGPGERLLQASYVADPVDGAAPSAIALALARLKAGELLSASSTS +FLTNVMSGTRTGKARLRAAVPVGWVLAHKTGTGQTAGFNDIGILTAPDGKAYSIAVMIGD +TPRPVRERQQLMQAVVASVVA-- +>[subseq from] Beta-lactamase class A VEB n=1 Tax=Parabacteroides chartae TaxID=1037355 RepID=A0A1T5BBF4_9BACT +--ELKKEIEIIVGGKDLKLGFALYDFSTGKSI-SINGNDRYPMQSVFKFPIGVALLDCVS +RGEFALSDSVTLTKADLLPWSPIRERWPEGVLPLVSVMTYMVAHSDNSATDFLIHKIGGV +ARIQDIVNRLGAKKINIRNNEAEIQGSWSVQFDNWTTPNAMVDFLRLMNDGKLLDKANTA +VLWEIMASASS--GSVNRLVPKTVTFARKTGYSGANAQNDVGIIELEDGRRVAYAIFLTD +STLGTDAGYDILAQIGKAIWKAy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Butyricimonas faecihominis TaxID=1472416 RepID=UPI000F57FB0E +-qGLEEQLRKVIANKKAQIGIAVI-INGKDTI-TINNDERYPMMSVFKLHQALAVADYCE +KKGLSFDTPIYIRKADLKTYSPLRDLYPNGELPIKKLLEYTLHLSDNNACDILFQQTGGT +EATDHYIRSLGMRHFAIKATEDEMHQDKNKCYQNWSTPLETARIIELLLNVRLFDDEYQG +FIKTTMMSCETGKDRLARPLQNKAIIGHKTGTGDRNGMNDVGFVYLPDGQSYTIAVFIKD +SEESEAATARIIADISKTVYRH- +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A0M3AXX1_9SPHN +------VVRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMAFLDAVD +RGKIRLSDSTTITKKDLTLHQPTAALVGNSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGYLARRYIRDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ +LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTEPIPTRWQLMQAVAKAVAA-- +>[subseq from] Beta-lactamase n=2 Tax=Dyella sp. 333MFSha TaxID=1798240 RepID=A0A1G7M2J6_9GAMM +--TLQASLQKLADQAPAKFGIIVVDLDGSAAA-KVNDDRAYMLMSTFKAPVSAAVLHQVD +TGKLRLDQKVHVTPADVTAGSPSIGARAAKGVTVSELMTAAVTQSDNTAVDALLKLVGGG +QVVTAYLKDKGVEGMRIDMDERAVGHAAIVMQENTTTLDGAATFLRKLQAGELLSAASTK +RLLDMMQAQVI-PNRIRAGLPAGFSIADKTGTGASNAWNDMAIITAPNGKRAVVGAFLRD +TTSTDEQRAAWFKELGTVVSK-- +>[subseq from] serine hydrolase n=1 Tax=Sphingobium bisphenolivorans TaxID=1335760 RepID=UPI0003A412FC +-----SVIRNLGQSFNGKVGIAVRRVGSDWTV-AWNGTSLFPQQSVSKLWVSMAFLDAVD +RGKIRLTDTTTITRKDLTLHQPTAALVGSSGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRSYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVEALAKLKEGDMLSSASAQ +LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDVGIMTAPDGTSYAVAVMIGS +TTESIPSRWQLMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=2 Tax=Sphingomonas sp. Leaf17 TaxID=1735683 RepID=A0A0Q4FPS4_9SPHN +-eALSARIDALARAFAGKAGIAIRAVDQGWSV-EAGGRQRLPQQSVSKLWVALTLMDLRD +QGRASLDTPITVRPQDLTLHQPIAMLVKGSGTTVGDLMVRALTHSDNTANDRLLNYVGGP +SAVRAMIERKRLGDIRFGPGERALQSAYIANPPDGAAPLAIADALARLARGELLSEGSTR +ILLDTMGRSVTGRARLRAALPPGWIIAHKTGTGQNAGFNDVGLLTAPDGNRYAIAVMIGD +TLRPIQERQQLIQAVAGAVAE-- +>[subseq from] Beta-lactamase n=1 Tax=Luteibacter pinisoli TaxID=2589080 RepID=A0A4Y5Z2R4_9GAMM +--HLQAALQKVADQAPGTLGVLVMDPAAGQSV-SVNAGRPYLMMSVFKAPIAAAVLSQVG +AGTLTLDRTVHLGPADVVDGSAVPGASLKAGVSVDELLHAAVTQSDNTAVDALLRLLGGS +PVATRFLASKGVQGIRIDMGEGELARAVLASHVDSSTLEGAGAFLRKLQAGELLSAGSTQ +KLLGMMSAQVI-PNRIRGGLPAGYQLADKTGTSGTRAFNDIGIITAPNGQKRVVVVFLAN +ARATPEQATKWFAEIGRLTA--- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Parabacteroides sp. TaxID=1869337 RepID=A0A354WXV1_9BACT +-eTLGHQLRQVINGKAATVGVAVI-FKGSELI-SINNMYRYPMMSTYKFHQALSVIDYLH +KHNENLATEILVKKSDLLAHSPLRDANPNGNITIGDLLKYSLIDSDNNACDILFKHIGGV +QVTEKYIHGLGIKDVAISQTEAKMMESENNCMLNWTKPSAAVLLLETFLQNQMFNKNEIL +FLERAMADCKTGNDKLKAGLPKQVLFAHKTGSSGRNADNDMGFVVLPNGQYYTIAVFVMN +SRETDKENAKLMADISRTVYEYf +>[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. ba1 TaxID=1522072 RepID=UPI0005685747 +--TLVSAIRNLGQGFRGKVGIAVRRIDADWTV-AWNGTALFPQQSVSKFWVALTFLDAVD +RGKLRLTDTTTITKNDLTLHQPSAAMVKAGGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRSYLARRMIKDVRFGPGERLLQANYLANPPDGAAPTAIVGALAKLKQGDMLSAESTR +LLLTVMGEAKTGPQRIKGGVPPGWAYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVLIGS +TTVSIPERWALMQGVAKAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium fuliginis (strain ATCC 27551) TaxID=336203 RepID=A0A292ZHM8_SPHSA +-----SVIRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD +RGKIRLSDSTTITKKDLTLHQPTAALVGNAGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRSYLARRYIRDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ +LLLSIMGEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTEPIPTRWQLMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas adhaesiva TaxID=28212 RepID=A0A2A4I652_9SPHN +--ALQARVAELVRAFPGKAGAAIRSVDDGWVV-GQGGDLSLPQQSVSKLWVAMTVLAQRD +AGRLKLDDPVLVSRDDLTLHQPIASLVKGEGTTLSGLLTRALTQSDNTANDRLLTYVGGP +TAVRRFLASKELTGIRFGPGERLLQSRYIDNPPDGASPNGITAALARLARGELLTETSTR +ILLDTMAASRTGHARLRAATPTGWQLAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TTAPMRDRQKLIQDVCAAL---- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Apibacter sp. B2912 TaxID=2656763 RepID=UPI001369B657 +-kSLEKKIHSITKNKKATVGVAVI-FDGKDTL-TVNNDMEYPAMSVFKFHQALALLDYMN +NNLLSLESNLYLKKSDIKKYSPLAKEYPEGNIPIGDLLNYTVSKSDNNASDALYYYMSGT +KMTDLYLRTLGSKNFSIQATEEEMSKDFNNQYINWTTPLEAARLLDIFINKDIFCKNYKD +FLFQAMTESETGSDKLKALLPKKVLIGHKSGSSSRNADNDIGFVYLPNGKQYSIAVFIKD +SKEDDKTNARIIADISQVVYNFy +>[subseq from] Serine hydrolase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A356THR2_9DELT +--ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD +AGRLDLGEMVRIRPGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP +AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS +LVLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR +TREPTPVRMEMMQEVVRAVVRY- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9BV01_9BACT +-qKLAATLNDVDGKLDGVLAVAVLDLSTGQKY-LLHADEVMPTASSIKIAILAELYRQAQ +QGKVKLTDFYTLQQSDMVGGSGITSVLTPGMLTLRDVAGLMISVSDNSATNVIIDRV-GM +ENVNALLDSLGLTHTRLRRKMMDIKAA-AEGRENVATPREMMLLLENLYRGKVLNKPMTE +DFFNLLSVHKE--SYIPRNLPEDVRVANKPGELE-GVRNDSGIVFTGKR-PYVISVMTTY +LRRE-RDGGEAITKISDAAYQMf +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=2 Tax=Pirellula sp. SH-Sr6A TaxID=1632865 RepID=A0A142Y5M6_9BACT +-aQLASQFDPLIRNHQGEVAVAIKNLDTGELY-QHNETTVMPTASLIKFPVLVELYRQVD +AGNLRLDRLVTLQDSDKVPGSGILTDHFQSGIPLETIARLMIRYSDNTATNLVLDQI-GM +ENTSKTMLQLGFRETRLHSKVFRRDTRSQKYGLGSTTAAEMLGLLELLHAKMLVSEKASE +QMLTHLASCED-DSKLVRDLPKAVKSFHKTGSVND-VRTDAGLFQTPKGT-LAIVVLTAK +NQGNANAAELLCAKIGSTAYEWf +>[subseq from] Beta-lactamase n=1 Tax=Anabaena cylindrica (strain ATCC 27899 / PCC 7122) TaxID=272123 RepID=K9ZDS1_ANACC +---LEPQIKALMNRYSLQTGMFFLDLDNGDYL-DIGGDRVFPAASTIKLPILLAFFQELD +AGRVSLDDKLTMRRDLVTNGSGVMQERVGKKYTALETITKMIVISDNTATNMIIDRLGGA +AKLNGRFRSWGLKNTVIRHLLGDFKGT------NTTSSQDMARALALLVNDKLVSSQSKE +QALDILRHTKT-RTLLPAGLGKGAIIAHKTGDIGF-LIGNAGFVTMPNGKHYLAAIFVKR +PYKD-VRGREFIREVSRLVYDY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Ag1 TaxID=1642949 RepID=A0A0M2LTS5_9SPHN +--ALDASIQQLVREFPGIAGVAVRAVDEDWTI-EAGGRRLLPQQSVSKLWVAMTVLDQRD +NGRLKLDDPVSVTASDLTLHQPVAYLVKGGTTTVGNLLFRALTQSDNTANDRLLTLVGGP +RAVNAFIERKRLGDIRFGPGERLLQAAYIDNPPDGAAPLAIADALSRLARGELLSETSTR +LMISTLESSRTGRARLKAGIAPGWTLAHKTGTGQNAGFNDVGLLTAPDGRRYAVAVMIGD +TTRPMRERQQLIQAVAASV---- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc minutum NIES-26 TaxID=1844469 RepID=A0A367QYW6_9NOSO +---LEPQIKTLMARYGLKTGMFFLDLDTGDYL-DIGGDRVFPAASTIKLPILIAFFQDLD +AGKVTLDEMLTMRRDLVTNGSGVMQQRVGKKYTALETINKMVTISDNTATNMIIDRLGGA +ARLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNDKLVSSTSKE +QALDILRRTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPSGKRYLAAIFVKR +PYKD-VRGRDFIRQVSHLVYDY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium wenxiniae (strain DSM 21828 / JZ-1) TaxID=595605 RepID=A0A562KDC6_SPHWJ +-eRLLAQFQSFAALSDGTVGIAVQDLSTGEEQ-SLNGDTLFPMASTYKVAVAGKILSMAD +AGVLALQDQVPLGPALL-----------AKARSVHDLIDLMLTHSDNDATDALVARAGGP +AAVDGWVKALGVKALRVDSDTAHLLYAFTLDPRDTATPRAMNALLAAIQLGKALKPASTV +YLLGMMERCHTGKARLKGMLPPGARIAHKTGSLN-GYGGDVGIVTLSDGRMFAISVFVMK +DYRGRETRDRIMAQAARAAYDYf +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A0C5XJA7_SPHYB +-----SVIRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD +RGKIRLSDSTTITKKDLTLHQPTAALVGNAGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRSYLARRYIRDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ +LLLSIMGEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTEPIPTRWQLMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. AE3 TaxID=2594473 RepID=A0A516IRI8_9SPHN +--ELREQISSLSRAFPGIAGVSVMSIKDGWQI-GYNDRKLFPQQSCSKLWVAITALDAVD +RGRVSLNDRVTIGRDDLTLHQPIRTKVLGNGTTLGALLQSAITESDNTANDKLMRSVGGP +LAVRDMIDSKRLGSIRFYEGERALQSRYIADPYDGAAPQAVTQSLARLKRGELLSPASTQ +RLLSTMASTKTGALRVRAAMKPGWKWSHKTGTGQVGGINDIGILTAPDGTAYAMAIMTVP +SK-SDGAAQEFMQKIARAVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. NAP1 TaxID=237727 RepID=A3WE64_9SPHN +--RFEAMLRQIEGESNGTLGVELFDVSTGHSV-GINRDRRFGHCSSFKLSLAAMVLASDS +LGIVDADKRVMWSEDDLMAVSPFTTRRLIEGATLRELAEATQKFSDNAAANILLREYGGP +AALTAFWSGIGDNVSRLDRYEPALNNVPVAEYRDTTTPAAMARTVAALAYGEILPDEDRA +TLRQWMIDTPTGVRRVRAGLHEELVGGDKTGTSLESLYVDIGFVEPPADK---------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas ginsenosidimutans TaxID=862134 RepID=A0A2A4HXQ4_9SPHN +--ALQGRVSELIRAFPGKAGAAIRSVDEGWVV-GQGGDLSLPQQSVSKLWVAMTVLAQRD +AGRLKLDEQVLVTRDDLTLHQPIAALVKGEGTTLSGLLTRALTQSDNTANDRLLTYVGGP +AAVRRFLASKELTGIRFGPGERLLQSRYIDNPPDGASPNGITAALARLARGELLTETSTR +ILLDTMAASRTGHARLRAATPAGWQLAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TTAPMRDRQKLIQDVCAAL---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=D2WSB1_KLEPN +------------------------------------------------------------ +------------------------EKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLR- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf198 TaxID=1736299 RepID=A0A0Q5UYQ5_9SPHN +---LVNAISELHSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD +QGRIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDILSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TIRPMPERQRLIQQAAAAVAH-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. ABOLG TaxID=1985880 RepID=A0A430DKW1_9SPHN +--ALDASIQQLVREFPGIAGVAVRAVDEDWTI-EAGGRRLLPQQSVSKLWVAMTVLDQRD +NGRLKLDDPVSVTASDLTLHQPVAYLVKGGTTTVGNLLFRALTQSDNTANDRLLTLVGGP +RAVNAFIERKRLGDIRFGPGERLLQAAYIDNPPDGAAPLAIADALSRLARGELLSETSTR +LMISTLESSRTGRARLKAGIAPGWTLAHKTGTGQNAGFNDVGLLTAPDGRRYAVAVMIGD +TTRPMRERQQLIQAVAASV---- +>[subseq from] serine hydrolase n=1 Tax=Porphyrobacter sp. AAP82 TaxID=1248917 RepID=UPI0002D91EA4 +--TFEQRIADLANPALGRIGVAAVDLATGEEV-MVLGDQLFPMASTSKVAIAATYLEMVE +QGRFTLTSEFPLMLPVPSARFSTAKAPVRAGMPAIDLIELMITRSSNPATDALLAAVGGP +QAVNSWVQRKGLAPFSINRDIATLVRANFIDTRDAATPRAMVRLLAGLYRGEYLSEQSRQ +VILGAMSRTVTGKRRIPANIPLEARVSHKTGSLSN-TSSDIGIIECPDGRVIAVAIYATG +QGGK-LAREERIAAIARAVYDGf +>[subseq from] HGC-1 beta-lactamase n=1 Tax=Bacteroides sp. CAG:875 TaxID=1262752 RepID=R7AAN9_9BACE +---LYSNINHFIAQQKAEIGVAIIA-EGKDTL-TIGNNHHYPLMSVFKLHQALAVGNYCE +KHRISFDTLLTVSKTDLKRYSPLRDQHPNGEFSLKQLLQYTLHLSDNNACDILFRFMGGP +DVTDRYIRSLGIKDFSVQHTEEDMHRNLNLCYQNWSTPLATAEVIEALFTRPLFDKEHQE +FIKKSLITCQTGKSRIVRPLQKNVIVGHKTGTGDYNAINDAGFVLFPDGRRYTLVVFVKN +SQENPEHTEAIIAHISEMVYQAf +>[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. RSMS TaxID=520734 RepID=UPI0010F8A18F +-----SVIRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD +RGKIRLSDSTTITKKDLTLHQPTAALVGNSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRSYLARRYIRDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ +LLLSIMGEAKTGPQRIKGGVPPGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTEPIPTRWQLMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium J055 TaxID=2420338 RepID=A0A3M1SQG4_9CYAN +--DLQAEVEKMAAQNELNPGVLFVDLETGGYL-NLNDTHVFSAASTIKIPILVAFFQAID +EGTIRLDEELTLKPEQIVPEAGFMQYDPPGTYTALEVATAAIVASDNTATNMLIDRLGGT +ETLNQKFRSWGLTQTVLHNALPDLGGT------NTTSPQDLAKLILAVDRGKVISLPSRD +RLLEIMKETEN-DSLLPQGLGEGASIAHKTGTINS-ILADAGLVALPTGKRYIAVVMVER +TDGD-ERAGDLIRQISTVAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus subsp. aureus 71193 TaxID=1155084 RepID=A0A0E0VRK8_STAA5 +---------------------------------------------------------QVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +TKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Class A beta-lactamase n=1 Tax=Butyricimonas synergistica TaxID=544644 RepID=A0A1U7L984_9BACT +-qGLEEQLRKVIANKKAQIGIAAI-INGKDTI-TINNDERYPMMSVFKLHQALAVADYCE +KKGLSFDTPIYIRKADLKTYSPLRDLYPNGELPIKKLLEYTLHLSDNNACDILFQQTGGT +EATDHYIRSLGMRHFAIKATEDEMHQDKNKCYQNWSTPLETARIIELLLNVRLFDDEYQG +FIKTTMMSCETGKDRLARPLQNKAIIGHKTGTGDRNGMNDVGFVYLPDGQSYTIAVFIKD +SEESEAATARIIADISKTVYRH- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium fuliginis ATCC 27551 TaxID=1208342 RepID=A0A5B8CEN5_SPHSA +-----SVIRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD +RGKIRLSDSTTITKKDLTLHQPTAALVGNAGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRSYLARRYIRDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ +LLLSIMGEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTEPIPTRWQLMQAVAKAVAA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V585_9BACT +------------------------------------------------VMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPGDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTV---------------------------------- +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F1AW48_KLEPN +------------------------------------------------------------ +-----------------------SEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYL-- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf198 TaxID=1736299 RepID=UPI000AE6C8A9 +---LVNAISELHSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD +QGRIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDILSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TIRPMPERQRLIQQAAAAVAH-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf242 TaxID=1736304 RepID=A0A0Q4R8F1_9SPHN +---LVNAISELHSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD +QGKLRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDILSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TIRPMPERQRLIQQAAAAVAH-- +>[subseq from] Beta-lactamase class A n=1 Tax=Microcoleus sp. PCC 7113 TaxID=1173027 RepID=K9WJP5_9CYAN +---LEPQIKALMARYSLQTGMFFLDLDTGNYL-DISGDRVFPAASTIKLPILIAFFQALD +EGKVNLNETLVMRRDLMTNGSGTMQYRAGKKFSIRETVTKMITISDNTATNMIIDRLGGR +AKLNQRFQSWGLKDTVIRNMLGDFKGT------NTTSPKDLVRLLTLVANQKLLAPSSRE +QALEILRNTKT-RTLLPAGLAPGAEIAHKTGDIGF-LIGDAGMIEMPNGKRYLAGIFVRR +PYKD-VRGRDFIRQVSQTVYNY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. WZY 27 TaxID=2283317 RepID=A0A369VT65_9SPHN +---LVETIGDLGRNFGGKVGIAVRAVDGGWSA-DSNGSLLLPQQSVSKLWVAMTVLDQVD +RGRLSLDTPLVVRSEDLTVHQPMAMLVKGDGTDVRELLRRALTTSDNTANDKLLQTVGGP +EAVRGFIQRKGLGAIGFGPGERLLQAAYVDNPPDGAAPSAIAFALAALARGELLSPASTR +YLLSTMEASRTGPQRLRGAVPASWTSAHKTGTGQTAGYNDVGLLTAPDGTRYAVAVMIGD +TRRSIPQRQALMQAVAAAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Proteobacteria bacterium SG_bin5 TaxID=1827382 RepID=A0A1W9H2C1_9PROT +---LQNSVQLLVRQFPGKVGIAVSSVDQGWLL-SANGDVRLPQQSVSKLWVAMTVLDGID +AGRFTLDTPVKVTREDLTLHQPIAAMVKPGKTTVGDLLQRALTQSDNTANDRLLRFVGGP +EAVRGFIAKKGLGNIRFGPGERLLQAAYVADPPDGAAPAAIATALARLKKGELLRAFTTG +YLIATMESSKTGKMRLRGAVPPGWSFGHKTGTGQTAGYNDVGILTAPDGRSYTLAVMIGD +TRRPIAERQALMQQVVASIVAY- +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. OF04-15BH TaxID=2292281 RepID=A0A416GGM6_9BACE +-qDLKQSILHYLTDKQAEVGVAVI-FNGTDTL-TVNNDNRYPLMSVVKFHQALAVADTLT +ALSETVDHKVLVTPEDLKPYSPMRDRYPQGNLPLRTLLEYTLQQSDNNACDLLFRLYGGP +QATDRYIRSLGLTDFAVQVTEDDMHRDTQTCYDNWSTPLEAVRLLEIFLKKPLFAQPIQE +FLKTTLMECEIGTDRLPAPLATGARIGHKTGTSDQDAINDMGFVLLPDGRYYTIAVFVKH +SRESAENTARIIADISRLVYSSf +>[subseq from] Beta-lactamase class A n=2 Tax=unclassified Sphingomonas TaxID=196159 RepID=A0A4R2S117_9SPHN +---LVNAISELHSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD +QGKLRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDILSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TIRPMPERQRLIQQAAAAVAH-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Altererythrobacter namhicola TaxID=645517 RepID=A0A1C7D924_9SPHN +-qDLSEQIAALGEGFDGEAGLAFRDNQTGRII-HYQGDALYPQQSVSKLWVAMAALAQAS +AGELDLQDSVTIRRADLTVYQPIRSIVRQQGTDYADLLSRALTRSDNTANDVLLRRVGGP +EAVQAWLNGAGLGAIRFGTDERTKQSGYLSAPMDGASPVLMAVALGRLAEGNLLDTVSTE +LLLSTLEETRSGPKRLKGGLPDGWTIAHKTGTGQQSGYNDVGILTAPDGRTYTVVAMIRR +TSAPNGQRMELMQELVRAVG--- +>[subseq from] CepA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SY47_9BACT +-eTLGEQLRQVIQGKAATVGVAVIF-NGSELV-SVNNMYRYPMMSTYKFHQALSVVDYLH +KHDKNLATEILVKKSDLLAHSPLRDANPNGNITVGDLLKYSLIESDNNACDILFKYIGGP +LVTEKYIHGLGIKDVAISQTEAKMMESEDNCMLNWTKPSAAVLLLETFLQNQMFSKNEVL +FLERAMADCKTGNNKLKAGLPKQVLFAHKTGSSGRNADNDMGFVVFPNGQYYTIAVFIMN +SRETDQENAKIMADISRTVYEYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. 20006FA TaxID=2056888 RepID=A0A197BT17_9SPHN +-----SVIRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD +RGKIRLSDSTTITKKDLTLHQPTAALVGNAGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRGYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ +LLLSIMGEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTEPIPTRWQLMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. SA916 TaxID=1851207 RepID=A0A2K0XW28_9SPHN +-----SVIRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD +RGKIRLSDSTTITKKDLTLHQPTAALVGNAGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRGYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ +LLLSIMGEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTEPIPTRWQLMQAVAKAVAA-- +>[subseq from] CepA n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SVM0_9BACT +-eTLGEQLRQVIQGKAATVGVAVIF-NGSELV-SVNNMYRYPMMSTYKFHQALSVVDYLH +KHDKNLATEILVKKSDLLAHSPLRDANPNGNITVGDLLKYSLIESDNNACDILFKYIGGP +LVTEKYIHGLGIKDVAISQTEAKMMESEDNCMLNWTKPSAAVLLLETFLQNQMFSKNEVL +FLERAMADCKTGNNKLKAGLPKQVLFAHKTGSSGRNADNDMGFVVFPNGQYYTIAVFIMN +SRETDQENAKIMADISRTVYEYf +>[subseq from] HGE-1 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=C8C0F1_9ZZZZ +---LESRLRRIIRLSNTDVGVAVISGSRNWAV----GNRKRPLLSVFKFFIAVQTLRQME +QTGTALNAKLTVEENMTDAYSPMLKKHPRRPISLAELLEYMIAESDNNAADILLKYSGGT +GQLEKFLHDLGFSGIDIRVNEKQMNQKAENQYLNQAAPSDVAGLIKLVLEKDVLSAEHRK +FLSDIMLKTSTGTDKIKQGLPPGVMFGHKTGSSSRTADNDAGFVTLTNGRTYYIAVMITE +SKLDDRANAALAAQISQTVYNY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas lenta TaxID=1141887 RepID=A0A2A2SG65_9SPHN +--ALIAAVEEAVRGFDGLAGAAVRAVDDGWTV-EANGRRPMPQQSVSKLWVALTLMEQRD +QGRVRLDDPITITRGDLTLHQPIAYLVAKNGTTVGDLLNRALTQSDNTANDRLLTLVGGP +GAVRDFIANKRLGEIRFGPGERLLQARYVDNPPDGAAPLAIADALARLARGELLSESSTR +IMLDTMGRTVTGRARLRAAMPVGWKLAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TRASTTARQQLIQTVARAVT--- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf38 TaxID=1736217 RepID=A0A0Q4L6K5_9SPHN +--SLVNAISQLQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD +QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGP +SAVRGMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TIRPMPERQKLIQNAAAAVANY- +>[subseq from] Uncharacterized protein n=1 Tax=Erythrobacter sp. QSSC1-22B TaxID=1860125 RepID=A0A1A7QM44_9SPHN +--ALEEEIAALAAGFDGEAGLAVQDVATGRIL-HAQGDALYPQQSVSKFWVALAALNEAD +EGRFDLSETVTLRREDLTLHQPIREIVRTQGTDYGDLFDRALTRSDNTANDRILRRIGGP +ETVQEFIDDADLAGIRFGTDERTKQSAYLADPVDGASPIAMAHALGQLARGELLSSVSTE +LLLSTLEQTRSGPRRLKGGVPPGWTIAHKTGTGQQSGYNDIGIVTSPAGHEYAVVAMIRR +TGAPVPARMEMMQELVRAVVR-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WPQ5_9BACT +--DLTKQIAALCNDAQGEIGVTVIHVESGRTV-EFEGEKKLPLYSVFKLPLAVEVLKRVE +EKKISLDQKLHVDPADVAPGSQFNADLWRKPKTVAELLEFSIVRSDNTSSDKLLQLVVGP +AVVTERMRGLGFPQIDIVSTVREYAT--SRDKPNLATTANLARLLNRLQKGELLEPAHLS +LLLGFMERARTGERRLRASLPTGTPVAEKTGSGAD-STNDVGLITLPDGGHLAMAVLIHN +SKLTAEAQERLIAELAR------ +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X6Y1_9BACT +--HLAARYEQIAAQAKGRVGAASVVLEGGEET-CIRCDEHFPMQSVYKFPIAMAVLARVD +AGELKLDQKVAVSKNEYLAVSQLRDRSRDKDVELRELLELAVVKSDGTASDVLMRLLNGA +KEVMRFLASIGIDATSINDPEMALQKDWQVQYRNWMSPRGALKLLRAFHEGKGLSKQSHA +LLRDMLERSIRGEKRLKGLLPKETVMAHKTGTSGTAATNDIGIITLPNGKHLAVAVFVSD +SKGDQPMREGAIAALARLAWD-- +>[subseq from] Serine hydrolase n=1 Tax=Arthrospira sp. PLM2.Bin9 TaxID=2599626 RepID=A0A5Q4H9I8_9CYAN +-kDLKNQLESVAAASDVSPALMFLDLNTGGYV-GLREQSIVPAASTIKVPILVAFFQAVD +AGEIRLDEMLVMTENHQVGEAGIMQYQPPGTYTALETATKMMTISDNTATNMIIDRLGGF +QVLNQRFRSWGLTDTMARNPLPDIEGT------NKTTPRDMVNLFSQIHQGGLLSMTSRD +RLLRIMTETEN-NHLLPSGVGNGAVVAHKTGTLNI-MLADVGIVDMPNGKRYILAILAER +TNG-NQAAESMIQKMSRQVYEY- +>[subseq from] serine hydrolase n=1 Tax=Sphingobium estronivorans TaxID=1577690 RepID=UPI00123951A2 +-----AVVRNLGQSFHGKVGIAVRRVGSDWTV-AWNGNSLFPQQSVSKLWVSMTFLDAVD +RGKIRLSDSTTITRKDLTLHQPSAAMVGANGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRGYLARRFIKDIRFGPGERLLQSNYLASPPDGAAPSSIVEALAKLKQNDMLSPASSQ +LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTESIPTRWQLMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. RF31YmG TaxID=1932668 RepID=A0A252CY76_9NOSO +-kALEPQIKALMNRYSLTTGMFFLDLDTGNYL-DIGGDRVFPAASTIKLPILIAFFQDLD +AGKVRLDEKLTMRGDLVTNGSGEMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA +GKLNQRFRTWGLKDTVIRRLLADLRGT------NTTSSQDMARVLALLVNNKLVSDSSKE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKRYLAAIFVKR +PYKD-SRGRDFIRQVSQLVYNY- +>[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. Chol11 TaxID=1385763 RepID=UPI000BE4539D +------VVRNLGQSFNGKVGIAVRRIGADWTV-AWNGTSLFPQQSVSKLWVSMTFLDAVD +RGKIRLTDTTTITRKDLTLHQPTAALVGTSGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRSYLARRTIKDVRFGPGERLLQSNYLSNPPDGAAPSSIVKALAKLKEGEMLSPASSQ +LLMSIMSEAKTGPQRIKGGVPPGWKYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS +TTEPIPVRWQLMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. EO9 TaxID=2304063 RepID=A0A418YSV8_9SPHN +-----SVVRNLGQNFRGKVGIAVRRVGADWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD +RGKLRLTDTTTITRNDLTLHQPTAAMVGTSGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGFLARRMIRDIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKQGEMLSSASSR +LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTVGIPERWALMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. AAP5 TaxID=1523415 RepID=A0A4P6XBA9_9SPHN +--ALVANVAMLARQFDGRVGIAVRSIERGWSV-DTGGDQLLPQQSVSKLWVAMTVLDYRD +RGRLRLTDPVTLYRDDITLHQPIAALIKGDQTTVGELLQRALTMSDNTANDRLLRYVGGP +NAVRDFIQRKGLGDIRFGPGERLLQSRYVADPPDGAAPMAIAGALARLKRGDLLSPESTR +YLIGTMESSHTGKQRMRGAVPPGWSFGHKTGTGQTAGYNDVGLLMAPDGSSYAIAIMIGD +TPRPIPARQALMQAVVASVVA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Myroides profundi TaxID=480520 RepID=A0A0B5RJE9_9FLAO +hqELNNQINKVINTKNATVGVAIIY-DAKDTL-TVNNNHKYPTMSVYKFFQALNILDYMD +KHNISLDTEIFIKKEDLQEYSPLRDKRPMGDISLGELIQYAASHSDNNVSNLFFKSLIGP +KMTDLYFRTLGIKEFEIVSSEEEMSLDFNNQYQNWITPLEATRILEMFRKEELLSPKYNN +FLRQAMIDTKSGQDKVKALLPKNTLVVHKTGMSFRAADNDLAIVYLPNGKQFSIAVLVMD +SKESDQTNAAIIAEIAKLTYDYf +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 106C TaxID=1932667 RepID=A0A252DQR4_9NOSO +-kALEPQIKALMNRYSLTTGMFFLDLDTGNYL-DIGGDRVFPAASTIKLPILIAFFQDLD +AGKVRLDEKLTMRGDLVTNGSGEMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA +GKLNQRFRTWGLKDTVIRRLLADLRGT------NTTSSQDMARVLALLVNNKLVSDSSKE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKRYLAAIFVKR +PYKD-SRGRDFIRQVSQLVYNY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. XS-10 TaxID=2599297 RepID=A0A518RLK8_9SPHN +--ALTATIASLAKEFGGVVGISVRSLDWGWQV-DANGQRPMPQQSVSKLWVAMTVLDARD +KGRLTLDDPVTVTRDNLTLHQPIASLVVKNGTTVRELLLRAMQSSDNTANDRLLTLVGGP +QAVRAFIAEKGLGAIRFGPGERLLQAAYIADPPDGASSSAIALALARLKAGELLSPASSN +FLINVMQGARTGRARIKGATPPDWKWGHKTGTGQTAGFNDVGVLTAPDGKAYSIAVMIGD +TSRPVRERQELMQAVVTSVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9XB95_9BACT +------------------MGVAILDLTGGQKF-LLHADDVFPQASSIKIAVLAELYHQAQ +QGKLKLADLYTMQQSDLVPDSDIMGGLTPAIITLRDLATMMVAVSDNSATNVLIDRV-GM +ENVNAFLDSLGLTHTRLRRKMMDLKAAG-EGRENIATPREMMVLLEALYRGKVLNKEMTD +DFFKMLSTHK--DSWMPRDLPEDTRVANKPGSLE-GVRNDSGIVFAKNR-PFVICVMTTY +LR-DEREGEKAITRIGLAAYRMf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. Ant17 TaxID=1461752 RepID=A0A013VN19_9SPHN +-----STIRNLGQGFRGKVGIAVRRVDADWTV-AWNGNALFPQQSVSKLWVALTFLDAVD +RGKLRLTDTTTITKNDLTLHQPSAAMVKTGGTSYSDLMRRAMTRSDNTANDTLLRAVGGP +EAVRGYLARRMIKDIRFGPGERLLQSNYLANPPDGAAPTAIVGALAKLKQGDLLSADSSR +LLLSVMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVLIGS +TTVSIPERWALMQGVAKAVAA-- +>[subseq from] serine hydrolase n=1 Tax=Limnoraphis robusta TaxID=1118279 RepID=UPI00066BC90B +--NLKQQILALTENSNLKPGVLLLDLDTGGYV-DINSESAFMAASTIKVPILVAFFQAVD +EGKIRLDETLTMQDQHIAGGSGDMQYKPAGTFTALETATKMIVVSDNTATNMLIERLGGA +EFINQKFLDWGMKNTVIRDVLPDLRGT------NKTTPRDLVNLLTQLNQGGLVSMKSRD +RIFRIMEKTEN-DSLLPSGLGKGAVIAHKTGNLKL-VTGDVGLIDLPNGKRYLLAVIVER +NEED-SAAESLIRNISKTVYEDf +>[subseq from] Class A beta-lactamase n=1 Tax=Barnesiella sp. An55 TaxID=1965646 RepID=A0A1Y3WD69_9BACT +--TVSHRIEQLLQDKSATVGVACSI--NGQNF-AFNDTVRYPLMSVFKLHVAVAVLQRME +ADGTRLDEILHIDSTQMRRYSPLLDRYPSGCISYAQLLHYALALSDNNACDLLIARAGGI +DAVKSCIDRAGITGYDLTETEASMHANIPACYRNWGHPSSVVQLLQKIHDGALLNEEHTR +FICSTLVEISTGTNKIRAGLPSDITLGHKTGSSGTIADNDAGFIVLPDGRVCYLTVFVKD +SRESDATNADLIAQITRIIYR-- +>[subseq from] Serine hydrolase n=1 Tax=Hormoscilla sp. GUM202 TaxID=2480853 RepID=A0A533P1N3_9CYAN +--SLRQEVQTLAAANELIPGVFILDLDRGAYV-EVNSSSTFAAASTIKLPILVAFFQDVD +AGLLRLDEQLTLRREHVATGSGSMQYHQGTQYSALEAARMMITISDNTATNMLIEGLGGI +DVLNQRFKSWGLRTTVLRNPLPDLEGT------NTTNPRDLAYLMARINQGNLTSGRSRD +RMLEIMERTET-TPLLKPGLGEGATIAYKTGNIGS-MIADVGLISLPKGKRYIAAVMVNR +PFND-DRARELITQISRAAYR-- +>[subseq from] Beta-lactamase n=1 Tax=Calothrix sp. NIES-2100 TaxID=1954172 RepID=A0A1Z4H4P4_9CYAN +-kALEPQIKALMNRYSLQTGMFFLDLDTGNYL-DIGGDRVFPAASTIKLPILIAFFQDLD +AGKVRLDEKLTMRGDLVTNGSGEMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA +AKLNQRFRSWGLKDTVIRRLLADLRGT------NTTSSQDMARVLALLVNNKLVSLSSKE +QALDILRHTSI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVKR +PYKD-SRGRDFIRQVSQLVYNY- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus fluminis TaxID=511487 RepID=A0A3M8DT06_9BACL +--SLQEKLEAVLSESSAVFGVTVKHIGTQEEA-RINADRYFQMASTFKVPILAALFRDVE +AGRLRLEDRIRLTEDDLVAGSGVLKEFLPGVVAIRDLAMLMIIVSDNVGTDKVVELV-GK +ERVEAFMRELGLNGISVKFDCWELLSFQPSPENNVATPSDMGRLLELIATGQLVSQEACD +GILDIMKRQQL-RNRIPYSLPDKTVIACKSGTIGS-VVNDVGIVYLPDKGAFTIAAMSQG +NG-TMKEGEQLIARLALTAYEHf +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. CENA543 TaxID=1869241 RepID=A0A2I8A1Q4_9NOSO +--QLDTEIKRLMSRYSLAPGMFFLDMETGEYL-DINGEKIFPAASTIKFPILIALFQEID +AGRVSLNETVVMRRDLMTGGSGNMQYKPGTKFSLLETATRMMTISDNTATNMVIDRLGGK +NKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRVAALIANNKLLSSNSHD +KVMDIMVRCKN-RSLLPAGLGKGAVIAHKTGTLGR-VLGDAGIIETPSGKRYLAGIMVAR +PFGD-ARARSFINQVSRLVYG-- +>[subseq from] Beta-lactamase class A n=1 Tax=Pyrinomonas methylaliphatogenes TaxID=454194 RepID=A0A0B6WUT6_9BACT +--DLRGQISALIRASGAKVAVAFHDLETEREL-LIDADESFHAASTMKVPVMMEVFRQAQ +AGRLALDERLKVKNESIADGSPYSYRRVGSEATVRELVRLMITESSNLATNLLIERV-TP +KSVMELVHNLGADGMRVLRGVEDGK-AYARGLNNTTTARALMILLKAIAEERAISPQASA +EMREILLAQKF-NEGIPAGLPPGVRVAHKTGSITR-IYHDAGIIYVPGRKPYVLVVLTRG +IA-DEGRAHQLVADISRAIYQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Crocosphaera chwakensis CCY0110 TaxID=391612 RepID=A3IUA3_9CHRO +--ALKEKIQKIDAKYNVKPQAWFIDLDNGAYV-TYNGTQPIPAASTIKIPVLVAFFQEVD +KGNMHLDQMLTMTKDVMVSGSGDMQYMQENKFPAIEVATKMIIISDNTATEMLVKQIGGK +EVLNQRFKEWGMKHTEIHNILPDLEGT------NKTSSEDLAKLLARIERGDLISTRSRD +RLIAIMEGTKT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER +AYND-PAGRSLIQDISRTVYQHf +>[subseq from] Uncharacterized protein n=1 Tax=Phenylobacterium sp. RIFCSPHIGHO2_01_FULL_69_31 TaxID=1801944 RepID=A0A1G2WAU2_9CAUL +--ALQARLDELAAAYGEEVGIAVTDVTQGWTA-GVDHERPYPQQSVSKLWVAIAVMKAAD +EGRLDPYGWVTLTEEDRSVYQPVSYRIGAGGTPISDLLRRALVESDNAANDKLMRELGGP +EGVAATLEGMGLTGVKVGAYERDLQAAYLADPLDGAAPGEVTTALAALSRGELLSPQSTE +WLIGLMAQARTGPRRLKGGLPAGWTIAHKTGTGQSVGINDVGLITAPDGHVYAVAVMMRH +TRKPVPERLAFMQAITRAVAEQw +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas sp. PP-CE-3A-406 TaxID=2135659 RepID=A0A3M0FNV5_9SPHN +---LVNAISELHSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD +QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTIGDLLTRALTHSDNTANDRLLARVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDILSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TIRPMPERQRLIQQAAAAVAH-- +>[subseq from] Probable beta-lactamase n=1 Tax=Arthrospira platensis (strain NIES-39 / IAM M-135) TaxID=696747 RepID=D5A0K8_ARTPN +-kDLKNQLESVAATSDVSPALMFLDLNTGGYV-GLREQSIVPAASTIKVPILVAFFQAVD +AGEIRLDEMLVMTENHQVGEAGIMQYQPPGTYTALETATKMMTISDNTATNMIIDRLGGF +QVLNQRFRSWGLTDTMARNPLPDIEGT------NKTTPRDMVNLFSQIHQGGLLSMTSRD +RLLRIMTETEN-NHLLPSGVGNGAVVAHKTGTLNI-MLADVGIVDMPNGKRYILAILAER +TNG-NQAAESMIQKMSRQVYEY- +>[subseq from] Beta-lactamase n=4 Tax=Sphingobium TaxID=165695 RepID=A0A081T4H2_9SPHN +-------VRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD +RGKIRLSDSTTITKKDLTLHQPTAALVGNSGTTYSDLMRRAMTQSDNTANDALLRAVGGP +DAVRGYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ +LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTEPIPTRWQLMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=2 Tax=Sphingobium francense TaxID=332057 RepID=A0A4Q4J9Z1_9SPHN +-------VRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD +RGKIRLSDSTTITKKDLTLHQPTAALVGNSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRGYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ +LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTEPIPTRWQLMQAVAKAVAA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Alistipes sp. TaxID=1872444 RepID=A0A358RBJ6_9BACT +-eQFERRIDRILEPCEATVGVAVLAPD-GTPI--TRNDRPLPMLSVFKFPVALAVLDRAV +REGISLSTPVAVGPEWLDSYSPMRDSLPPQGLPLGRLLAYAVSQSDNIACDRLIDFAGGP +GAVDGYLKRLGITEIRITATERTMHLATENQRINTARPSALCSLFDRFLQVELLPQRETA +WLRGLLEGCATGRNKLRAGLPPEVRLGHKTGSSDRTADNDAGYVVLPDGRHYCITVLVTD +SHHDDARNAGVIAAISEAAYEYf +>[subseq from] Serine hydrolase n=1 Tax=Clostridia bacterium BRH_c25 TaxID=1734399 RepID=A0A101W818_9FIRM +---FKKNLEEIINSSNANIGVAIKNMNTGETI-MINEGLAFRSASTIKLLIMSEILKEVK +EGEHTLDEPVVFADSIKVGGCGILKELNSGHFTIEEIITLMIILSDNTATNILIDMS-GM +DRINSMALELGLKNTELQRKMMDFEAA-KAGKENKTCAEDMMRILELIYNGENIDEKYSS +IMLDILKRQQI-VGRLDLYLPEDTVIAHKTGDLDK-LEHDVGIVFLPNCT-YIICVLTSE +NN-SNREGQEIIGKISQLVYNSy +>[subseq from] Uncharacterized protein n=1 Tax=Calothrix desertica PCC 7102 TaxID=232991 RepID=A0A433V414_9CYAN +--SLKSAIQNLAIQNNLTPGVFVTDLDNGGYV-DFNGGAMFSSASTIKLPILIAFFQDVD +EGKINLEETLRTSKSTVAGGSGDMQNRPGTQYGILEVATKMMTISDNTATNMLIERMGGI +EKLNERFRSWGLNTTLLGNILPDIEGT------NKTSPKELSNLMAMITKGNIVSSQSRE +RIIDIMQRTVK-DTLLPAGLGQGAKIAHKTGEIG-GILADTGLVELPSGKRYLISVMVQR +PRND-VSAEKLINGISRAAYQQf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium chlorophenolicum L-1 TaxID=690566 RepID=F6ET74_SPHCR +-------VRSLGQSFNGKVGIAVRRVGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD +RGKIRLSDSTTITKKDLTLHQPTAALVGNSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRGYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ +LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTEPIPTRWQLMQAVAKAVAA-- +>[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Parapedobacter indicus TaxID=1477437 RepID=A0A1I3CNX1_9SPHI +--TLRKDIERILANYQARIGIAVHNQDFSDSL-IVAGNYHFPFQSVYKFHLGIAVLNQVD +NGILKLDQPIRVSKAAVTTYSPIKDKYPDGVLPLSEVIKYTIAESDNVGCDILFELLGGP +DAVQAYFSDKGYGNLSIKLTEAVQQKEWDLQFANWTTVGSCNHILYDYYTKRLLSPTSHQ +FLWDTMRGTKTGVNRIKGDLPTGTVVAHKTGYSGTAAVNDIGVVSLPNGDVFYMTVLVTD +SKEEESVSAKAIAEVSKAAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus fluminis TaxID=511487 RepID=A0A3M8DI39_9BACL +--ELQEKLERIAREMPGTFGVAIKHLETGEEA-SLFGDELFQLASVFKIPILATLFRDVE +EGRLSLGERVKLQADERVPGSGVLQELDPGAVTIKDLAMLMIIVSDNYGTDQVLKHV-GI +ERVNRFMNELGLVKTNIQHDCWRLLTLEPRPENNVSTPQEINRLLEMIAKKQLISEAACD +GMLNILKRQQF-TSRIPNLLPGQARAAHKTGTIGS-CVNDAGIVYMPQGKGAFAITVLSR +DNESTNQGAQTIARLSRAAYDHf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. CCH9-F2 TaxID=1768778 RepID=UPI00082EF4BF +--ALQGRVSELIRAFPGKAGAVIRSVDEGWVV-GQGGDLSLPQQSVSKLWVAMTVLAQRD +AGRLKLDEPVLVTRDDLTLHQPIAALVKGEGTTLSGLLTRALTQSDNTANDRLLTYVGGP +AAVRRFLASKELTGIRFGPGERLLQSRYIDNPPDGASPNGITAALARLARGELLTETSTR +ILLDTMAASRTGHARLRAATPAGWQLAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TTAPMRDRQKLIQDVCAAL---- +>[subseq from] serine hydrolase n=1 Tax=Planktothrix tepida TaxID=1678309 RepID=UPI0009340622 +--DLKTAILALAQDSKLKPGVFLVDLDTGNYV-DISGETPIPAASTIKVPILVSFFQAVD +EGRIRLDEILTMEEKHIAKGSGELQKPVGSKFTALETATLMITNSDNTATNMIIDRLGGI +ESLNQQFVSWQLKQTQMQNILPDLEGT------NKTSSKDLVTLMAEINQGKLVSVKSRD +FMLRIMQQTRN-RSLLPSGLGEGAFIAHKTGNIDT-VSGDIGLVDMPNGKRYLVGVLVQR +EA-DDPQAEELIRQISSTIYQYf +>[subseq from] Penicillin-binding protein, transpeptidase n=1 Tax=Planktothrix tepida PCC 9214 TaxID=671072 RepID=A0A1J1LNE4_9CYAN +--DLKTAILALAQDSKLKPGVFLVDLDTGNYV-DISGETPIPAASTIKVPILVSFFQAVD +EGRIRLDEILTMEEKHIAKGSGELQKPVGSKFTALETATLMITNSDNTATNMIIDRLGGI +ESLNQQFVSWQLKQTQMQNILPDLEGT------NKTSSKDLVTLMAEINQGKLVSVKSRD +FMLRIMQQTRN-RSLLPSGLGEGAFIAHKTGNIDT-VSGDIGLVDMPNGKRYLVGVLVQR +EA-DDPQAEELIRQISSTIYQYf +>[subseq from] Serine hydrolase n=1 Tax=Planktothrix sp. UBA10369 TaxID=2055760 RepID=A0A354WIV5_9CYAN +--DLKTAIMGLAKDSKLKPGVFLVDLDTGNYV-DIQGEEALPAASTIKVPILVSFFQAVD +EGRLRLDEVLTMAEKHIAKGSGELQDQPGSKFTALETVTLMIENSDNTATNMLIDRLGGI +ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSAKDLVNLMAEINQGKLISLKSRD +LMLRIMEQTRN-RSLLPSGLGEGAFIAHKTGNIDS-VSGDIGLIDMPNGKRYLVGVLVQR +EAN-DPQAPELIRQISSTIYQYf +>[subseq from] Beta-lactamase n=1 Tax=Limnoraphis robusta CS-951 TaxID=1637645 RepID=A0A0F5YMC3_9CYAN +--NLKQQILALTENSNLKPGVLLLDLDTGGYV-DINSESAFMAASTIKVPILVAFFQAVD +EGKIRLDETLTMQDQHIAGGSGDMQYKPAGTFTALETATKMIVVSDNTATNMLIERLGGA +EFINQKFLDWGMKNTVIRDVLPDLRGT------NKTTPRDLVNLLTQLNQGGLVSMKSRD +RIFRIMEKTEN-DSLLPSGLGKGAVIAHKTGNLKL-VTGDVGLIDLPNGKRYLLAVIVER +NEED-SAAESLIRNISKTVYEDf +>[subseq from] Serine hydrolase n=1 Tax=Leptolyngbya sp. IPPAS B-1204 TaxID=2483801 RepID=A0A3M9ZEU8_9CYAN +-----------------VPGVYVMDIDNGDFF-SFNGNATFSAASMIKLPVLIAFFQDVD +AGKIKLDEMLQIQQTDVAEGSGDMQYGVGTQYSALETATNMIVSSDNTATNMVIRRLGGI +QALNQRFRQWGLQQTLLRKPLPDLEGT------NTTSPKELASLMALLNDGKLISMKSRD +RAFEIMRRTAN-DSLLPSVMSPGSAIAHKTGDIGS-MLGDIGLVDLPSGRRYAIATMVKR +PHND-ARAQDLIRQIAAIVYEHf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. 3P27F8 TaxID=2502213 RepID=UPI0010F91BF2 +--ELVARVDALVRSFPGIAGVAIRAVDEGWTV-ESGGRRRMPQQSVSKLWVAMTVLDQRD +SGRLRLDDPVTIYPADLTLHQPIASLVKPGGTTVSALLTRALTQSDNTANDRLLTLVGGP +AAVRSFIERKQLGDIRFGPGERLLQSAYITDPPDGAAPLAIADALSRLARGELLSETSTR +FLLATMGSTVTGRARLKAALPPGWSLQHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TMRPMRDRQQLIQAAAGAL---- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium ummariense RL-3 TaxID=1346791 RepID=T0K1S1_9SPHN +-----SVVRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNQLFPQQSVSKLWVSMAFLDAVD +RGKLRLADTTTITKKDLTLHQPTAALVGNTGTTYADLMKRAMTQSDNTANDTLLRAVGGP +DVVRGFLARRLIKDIRFGPGERLLQANYLANPPDGAAPSSIVAALAKLKEGDMLSAGSSR +LLLSLMEEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDVGIMTAPDGTSYAVAVMIGS +TTEPIPVRWQLMQAVAKAVAA-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. YL-JM2C TaxID=1336744 RepID=UPI0004A8002B +--ALDAAIDRLGRRFPGDVGLAVRDVQTGWTS-HRRGLDYFPQQSVSKLWVSLTALDQVD +GGRLDLSRALTVTAKDLTLHQPIRALALRPGTTGDDLMVRALTQSDNSANDRLLHQVGGP +DAVRATLRGKAIAGIRFGPGEPRLQAEYLADPIDGATPIAMVDTLARLRRGDLLSPASTA +KMTAIMEETRTGALRLKAGLKPGWRLAHKTGTGQQAGYNDVGILTSPEGRSYAVAVMIGR +TGRPLAERMKLMQSVVAATI--- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas taxi TaxID=1549858 RepID=A0A2W5B7T0_9SPHN +------------------------------------------------------------ +---------------------------------AAKVMELMIVRSDNRATDQLLAALGGP +VAIQQWLSSQKIPGIRMDRTIAQLLRGHLADSKDVATPVAMVTLLNTLDNGTVLTAQSRA +FLLELMSRCATGTRRIRALLPVGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAIFARG +GR----DRQPVIAEVARVIYDRf +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WMB9_9BACT +--DLQNKIETIISSTKADIGVAVMVPSSHDTI-LVNGMKPYTMMSVVKFPQAVYILSLVD +RGKLRLSQKVNFDAAELQRHSPMRDKYGKDPVTLEETIMWAVSHSDNIACDRLFELGGGV +AANEKYFQDLGYHDFAIGVDYKHLDEK--TMRANNTSPLTMTRILERFYNGKLLAGSSRN +LLLKFMTQSQNPEDRIKGNLPKGTVVAHKTGTSANGVFNDVGIITLPSGKQIILSVFVSA +SKEKSDDNAKAIAAIAKAVFDHy +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. HDW15C TaxID=2714944 RepID=UPI00140B1F86 +------------------------------------------------------------ +--------------------------------SARSLMRRMLIHSDNGATDVLIRDLGGP +QALDSWLKDNGVQGLRVDRTIAQLLRDKRWDRRDSSTPTAMVDLLRRIYKAELITPKSRN +YLLDVMGQCQTGKNRIKGLLP-GVPVEHKTGTLN-GYSSDVGFITMPDGRRVAVAFFARG +GD----DRPRTIAQAARAIYDGf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. HDIP04 TaxID=428994 RepID=T0HGJ1_9SPHN +-------VRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD +RGKIRLSDSTTITKKDLTLHQPTAALVGNSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ +LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTEPIPTRWQLMQAVAKAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudanabaena sp. ABRG5-3 TaxID=685565 RepID=A0A2Z5WTQ1_9CYAN +---LVSKIKELAKEKDLSMQMMMVDLDSGAYV-QIGANQVIAAASTIKTPLLVAFFQDVD +AGKIKLDEQLEITDDVKVGEAGDFQFLPTGTISALETATQMIIISDNTATNMIIKRLGGN +AAVNQRFKSWGLNNVVVNNKLPDLEGT------NTISTQDMVTLLAMLDKGKLLEPRSRD +RFMDIMRRPVT-NTLLPKGIGEEARIIHKTGDIRS-AVGDAGIVDMPNGKRYAIAVMVKR +PDND-QRANELIRQISRATYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Caulobacterales bacterium 32-69-10 TaxID=1970503 RepID=A0A258FMK1_9PROT +---LTLRLEQLRKDFGGSVGIAVHDLQAGWTT-GSNGLAVLPQQSVSKLWVAIALLDAVD +RGEIDLAESVTVTPADLSVNQPIREKLAGGATTLGDLLAMQVALSDNAANDIVMRRVGGS +EAVQRTIAAKRLGAIRAGPEEKVLQPAYLADPDDGATPVALVEALARLKRGELLSPASTA +RLQQVMAQTSTGPMRLPAGLPMGWTISHKTGTGQSTGYNDVGLLGAPDGRTYAVAVMIGS +TTRPVPERMTLMATVAAAVVA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-CE-1A-559 TaxID=2135657 RepID=A0A4R2SV29_9SPHN +----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD +QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP +SAVRSMIARKQLGAIRFGPGERRLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGHRYGIAVMIGD +TIRPMPERQKLIQAAAAAVANY- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WL07_9BACT +--QLTERLKAITSSAGGVVGLAVTHIESGRTV-NIQGTLPLPLYSVFKLPLAVAVLKDVE +ENRLRLDRKVLTTPAEIVPGSQENTDLWRKPRTVTELLELSVMRSDNTSADKLLQLVGGA +SAVTERMRSLGYQNLLIHSSVREYVAD--RKKVNTGTASDLTRLLVDLHQGRILQPPQLS +VLLGFMQRATTGQRRLRDLLPAGTQVADKTGSGAAGATNDVGLITLPKGGHLAIAVLVSD +AKLPTEEQEKLIAEVARVSYDA- +>[subseq from] Serine hydrolase n=1 Tax=Pseudanabaena sp. SR411 TaxID=1980935 RepID=A0A256BFL5_9CYAN +-------VKELAKEKDLAMQMMVVDLDSGAYV-QVGANQPIAAASTIKTPILVAFFQDVD +AGKIKLDEQLEMTADVKVGEAGDFQFLPTGTITALETATQMIVISDNTATNMIIKRLGGF +TALNQRFKSWGLNNIVIKNQLPDLEGT------NTISTQDMVTLLAMLDKGKLIEPRSRD +RFMDIMRRPVT-NTLLPKGLGEEARIIHKTGDIGS-AVGDAGIVDMPNGKRYAIAVMVKR +PDND-QRANELIRQISRTTYEYf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus choshinensis TaxID=54911 RepID=A0A0Q3WH31_BRECH +--DLQKKIEELVGQATATFGIVIKHLETNEEV-KINEGHLFQMASCYKVPILATLFREVE +AGTIDLNTRVRLSLTDRVPGSGVLKEFDPGSVSLKDLATLMIIVSDNVGTDKILELV-GV +NHTDQYMKSIGLQDTYVNLTCWQLLSFTKSIENNVSTPADMALLLEKIARKELISKKACE +QMIDIMKRQHF-RDRIPNLLPAGTPVACKSGSVG-GVHNDIGIIYLPEEKGTVIVSAFSE +NNSSQLEAAQMIAKVAQSAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Phyllobacterium sp. OV277 TaxID=1882772 RepID=A0A1H0EPY3_9RHIZ +--ALQQRLEKLATGKDARIGICALD-QAGTSV-CVRGDERFSLQSVVKLIAGAATLDAAD +HGAVNIEDPIIIRSENLSLKQPLAKIVERNGTNAADLVRRAIVDSDSAAVDILIDRLGGT +GTINSFLAGKAISGIRIDRDERHLQTAYQKDPRDTATPRAMTEFLAALMNGKLISTGSTN +RLLAIMNETSTFPDRLRAGVGKDWSVAHKTGTSPNVATNDVGILTAPDGGKVAISVFVAD +SRETPTLRAMIIASAAQAVTEAy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F1AW47_KLEPN +------------------------------------------------------------ +-----------------------SEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIY--- +----------------------- +>[subseq from] Penicillin-binding protein, transpeptidase n=2 Tax=Geitlerinema sp. PCC 7407 TaxID=1173025 RepID=K9S5U5_9CYAN +---LKAEIQTIASQNQLSPAVLVVDLDSDAHV-DINAAVPLPAASTIKIPILVAFFQDVD +AGKIRLDEQLTMRQELVASGSGEMQYQPPGTFTALETATKMITVSDNTATNMLIERLGGM +ASLNQRFQAWGLPATALRNPLPDLEGT------NTTSPHDLVQVMALVNRGDLMSQRSRD +RLLSIMHDTVN-DSLLPQGLGEGAIIAHKTGDIGS-LLADAGLVDMPSGKRYLIAVMVKR +PH-NADAAYELIQQISKATYQ-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. YZ-8 TaxID=2319844 RepID=A0A494THN8_9SPHN +--RISAKIAELGRAFGPGVGISVRDIREGWST-SWNGDRLCPQQSVSKLWVALAVFDAMD +RGALRPDDAMIVTRNDLTLHQPIRALVGEQGATVSELLERQMTQSDNTANDMLLRRIGGP +TAIRSMLTRLRISNVRFGPGERLLQSAYAENPVDGAAPNAITLALARLVRGDLLTPTGTQ +NLLALMERSKTGRARMKAAIEPDWLLAHKTGTGQVAGFNDVGLLTAPDGHIYAVAVMVAR +SSRPIAERQAIIANVARAVIDDw +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. EhN03 TaxID=1849358 RepID=UPI00128FF08F +-rELDQAVSRIGGTFDGHVGIAVRDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD +AGRLDLSEMVAIRSADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA +EAVQDFLDTHGLASIRFGTDERSKQSSYLADPIDGAPPVALVEALARLQRGELLSAGSTG +LLLGTLARTKSGPQRLKAGAPEDWIVRHKTGTGQQSGYNDIGLFTPPSGRSYAIAVMIAR +TREPTPVRMEMMQQVVRAVAR-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9Q4A1_9BACT +-qKLEASITDVDRSLDGVMGVAIEDLNSGQKY-LLRGDDVFPQASSIKIAVLAELYRQAQ +QGKLKPTDVYTVKASDLVADSPIMNGLTPGVVTLRDLATMVVAVSDNSAANILIDRV-GI +ESVNSLLDSLGLAHTRLRRKMMDLKAA-SEGRENISTPSEMMTLLEDVYRGKVLNKPLSE +DFFRLLSTKKN--SWIPRELPEDLKVADKEGELE-GVRNDSGIVFLENS-PYILCVMTTY +LRR-ERDGEEAISKISVDAYRMf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9QDY2_9BACT +-qKLEASITDVDRSLDGVMGVAIEDLNSGQKY-LLRGDDVFPQASSIKIAVLAELYRQAQ +QGKLKPTDVYTVKASDLVADSPIMNGLTPGVVTLRDLATMVVAVSDNSAANILIDRV-GI +ESVNSLLDSLGLAHTRLRRKMMDLKAA-SEGRENISTPSEMMTLLEDVYRGKVLNKPLSE +DFFRLLSTKKN--SWIPRELPEDLKVADKEGELE-GVRNDSGIVFLENS-PYILCVMTTY +LRR-ERDGEEAISKISVDAYRMf +>[subseq from] serine hydrolase n=4 Tax=Sphingomonas TaxID=13687 RepID=UPI0008336EF6 +----VTGIDAIATEFGGKVGIAVKSIDEGWMV-AKNGDQRMPQQSVSKLWVAMTMLDARD +KGRVRLEDSVTITRNDLTLHQPIAGLMKDGSTTVGELFRRAMTMSDNTANDRLLQLVGGP +QAVRGFIADRNLGNIRFGPGERLLQSSYVAEPIDGAGAAAIANALARLKRGELLSAGSTT +LLISTMQESRTGRARLKGAVPAGWVLGHKTGTGQTAGFNDVGILTAPDGKSYAIAVLIGD +TRRPIPERQQLMQTVVASVVA-- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter pelagi TaxID=994320 RepID=UPI001323A67D +--RFEQELEEIAASLEGTVGIAVTDVETGRSY-AIRGDDWFPQQSVSKLWVALTALDEVD +QGRLELDEGVVIGPKDLTLHQPIRDLVRARGTDYADLIQRAITHSDNTANDRILRRVGGA +EAVEDFFAAKKITGVRFGADERSKQSGYLADPVDGAMPLGITRALARLARGELLSPASTA +LILATLNATRSGPQRLKGGVPPGWSIGHKTGTGQQSGYNDIGILTSPDGHRYALAVMIGR +TREPTLERMRMMQAVTVAT---- +>[subseq from] Beta-lactamase class A n=1 Tax=Cylindrospermum stagnale PCC 7417 TaxID=56107 RepID=K9X017_9NOST +-kALEPQIKALMSRYSLQTGMFFLDLDNGDYL-DIGGDRVFPAASTIKLPILLAFFQSLD +EGKVSLDKQLTMRGDLVASGSGVMQERVGKKYTALETITKMSVISDNTATNMIIDYLGGP +ARLNQRFRSWGMKDTVIRRLLGDFRGT------NTTSPQDLARALALLVNDKLVSSQSKE +QALDILRQTKT-RTLLPAGLGKGAVIAHKTGDIGF-LIGNAGFITTPNGKHYLAAIFVKR +PYKD-VRGRDFIRQVSQLVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Phormidesmis priestleyi ULC007 TaxID=1920490 RepID=A0A2T1D5T2_9CYAN +----KNNLQALVQQTQLSPGMMIVDLDTNAYL-NINASVALPCASTIKLPILVAFFQDVD +AGKIRLDEMLTMRSDLIATESGEMQQPVGSQFSALETATKMITVSDNTATNLLIDRLGGK +EALTQRFQSWGLTSTAIQNRLPDVEGT------NTSSSQDLVTLLGLVSNGKLLSMRSRD +RMLDLMRHTVN-NSLLPSGLGEGATISHKTGSIGS-MIGDVGLIDMPSGKRYLIAAMVKR +PRND-ERAEELIRQVSRLTYQYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf34 TaxID=1736216 RepID=A0A0Q4L9K9_9SPHN +--SLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD +QGRIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGP +SAVRGMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TIRPMPERQKLIQNAAAAVANY- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas viridiflava TaxID=33069 RepID=UPI0013DEA125 +-----------------RVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNVGDHVTRLDRWEPELNEAIPNDERDTTMPVA-------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Proteobacteria bacterium ST_bin14 TaxID=1978762 RepID=A0A1W9JVW9_9PROT +--QLVSTINALRAQFSGSVGIAVRSIDKGWTV-ASNGDAKLPQQSVSKLWVAMAVLDFRD +SGRLTLDDAVTVTREDLTLHQPIAMMVKGDGATVGELLQRALTTSDNTANDRLLRFIGGP +DTVRAFIQRKGLGSISFGPGERLLQSSYIANPPDGAAASAIAGALAMLKKGELLSAQSTS +YLIATMESSRTGKQRLSGAVPAGWHFGHKTGTGQTAGYNDVGILTAPDGQSYALAVMIGD +TPRPVPERQALMQSVVASVVAY- +>[subseq from] serine hydrolase n=1 Tax=Oxynema sp. AP17 TaxID=2064643 RepID=UPI001442E45C +--ALKTELQGLAAPHDLTPGIFVVDLDTGGYV-DLNGSSSFSAASTIKLPILIAFFQAVD +EGKVRLDQMLTMQAEQVAGGSGMRYSAPGTEYSALETATKMITISDNTATNMLIDLLGGA +EILNEQFRGWGLSSTQISNPLPDLEGT------NTTSPRDLVQLMSMVEQGGLVSLRSRD +RLLDILTATVN-DSLLPQGLGQDAAIAHKTGDIGT-SIADAGLVDRPDGKRYLIATLVKR +PHND-PQGEELIRQMSKAVYDSf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KJR1_9BACT +-------FQELEEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS +--IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFALLDGP +NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLAFNLKEYVTGDILSDDKKE +IFIDWMSNNATGDELIRAGV---------------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium J007 TaxID=2420339 RepID=A0A3M2GPK8_9CYAN +--ALKTELQGLAAPHDLTPGIFVVDLDTGGYV-DLNGSSSFSAASTIKLPILIAFFQAVD +EGKVRLDQMLTMQAEQVAGGSGMRYSAPGTEYSALETATKMITISDNTATNMLIDLLGGA +EILNEQFRGWGLSSTQISNPLPDLEGT------NTTSPRDLVQLMSMVEQGGLVSLRSRD +RLLDILTATVN-DSLLPQGLGQDAAIAHKTGDIGT-SIADAGLVDRPDGKRYLIATLVKR +PHND-PQGEELIRQMSKAVYDSf +>[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium zucineum TaxID=284016 RepID=A0A2W5PEB6_9CAUL +-eALQSRLDELAAAYGEEVGIAVTDVTAGWTA-GVDQDRPYPQQSVSKLWVAIAIMKAVD +EGRLDVESPVLLSEADRSVFQPVSYKIGANGTAMSDLLRRALVESDNAANDRLMRELGGP +EGVADTLHGMGLSSVKVGAYERDLQAAYLAEPLDGAAPAAITAALAALSRGELLAPASTQ +RLIGLMAEARTGPRRLKGGLPPGWSIAHKTGTGQSVGINDVGLLTAPDGRTYAVAVMMRH +TRHSVPERLAFMQSVTRAVAEQw +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E3MWZ1_9PLAN +----SQKLSSLLQDHEGNVSVAIKHLSTGERF-EFHANRTMPTASLIKIAVMVEAYRQAD +AGRIDMDQRITLLAGDKVPGSGILTTHFSAGLSLRDAIRLMISHSDNTATNLVLDQI-GI +RSTAETMEKLGFPNTKIHAKVFRRETRSKQFGLGSTTALETAHLLEQLYRRQLASPAASL +AMLKHLENCQD-RTKLPRFLDSHTKIAHKAGSLSR-VRTDAGIIFLSSG-PLVICVLTSD +NKTDENASEILCARVAKVACAHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf20 TaxID=1735685 RepID=A0A0Q4G7N3_9SPHN +--QLDAAIVALHQGFEGKSGIAIRAVDDGWTV-EVGGRQHLPQQSVSKLWVAITLLDLRD +QGKARLEDPVVVRPEDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLSYVGGP +RAVRGMILRKQLGEIRFGPGERQLQSAYVANPPDGAAPIAIADALARLARGELLSASSTQ +VLLDTMGASVTGRARLRAALPAGWRIAHKTGTGQNAGFNDVGLLTAPDGKRYAIAVMIGD +TLRPIRERQMLIQSVAAAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=[Leptolyngbya] sp. JSC-1 TaxID=1487953 RepID=UPI00068C1ABC +----------------LVPGVYVMDIDNGNFF-SFNGNATFSAASMIKLPVLIAFFQDVD +AGKIKLDEMLQIQQTDVAEGSGDMQYGVGTQYSALETATNMIVSSDNTATNMVIRRLGGI +QALNQRFRQWGLQQTLLRKPLPDLEGT------NTTSPKELASLMALLNDGKLISMKSRD +RAFEIMRRTAN-DSLLPSVMSPGSAIAHKTGDIGS-MLGDIGLVDLPSGRRYAIATMVKR +PHND-ARAQDLIRQIAAIVYEHf +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. ATCC 43529 TaxID=1840705 RepID=A0A367QMZ8_9NOSO +--ELKTPINKLVSRYKLTPGMFFMDLETGDYI-SINGNKAFPAASTIKYPILIALFQEVD +AGRIKLDETLVMQRKHVVGGSGSMQKRVGSKFSVLKTATMMMTISDNTATNMIIARLGGI +PKLNQRFRSWGLQNTALRRMLGDFNGT------NKTSAKDLVRLSALMVNNQLLSDKSES +QVLGIMYGCQN-RRLLPSGLGSGAKIAHKTGTLRF-VLGDAGIIQTSSGKRYLAGILVKR +PNHD-KRARDFIRQVSQVVYGYf +>[subseq from] Beta-lactamase class A n=1 Tax=Propionispora hippei DSM 15287 TaxID=1123003 RepID=A0A1M6BVY0_9FIRM +-kQLEQTIQQILTTCPCQQALLVRHLPSGRQF-ALNPDQVFPAASMIKLPIMYEVMRQAS +QGLLALEELLEVTEAVRVGGAGILQERPGIALTVQELVTLMIVISDNTATNLLLNRL-GL +AAVNNTAEQLGLTNTVLRRRMMDFAAA-RAGQENHTSAADIAKLLEIMYQQTTLPPEYGK +LMLNILKRQQI-RDKLPFYLPEDIAIAHKTGTLD-GVEHDAGILFSAGG-PYLISVMTAG +LPAN-YQGLQLVAQIGRAIFEY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. 66-10 TaxID=1895848 RepID=A0A1M2ZEY2_9SPHN +--ALAERIETLVRGFPGVAGIAIRAVDEGWTV-EYGARRLMPQQSVSKLWVAMTVLDQRD +SGRLRLDDPVTLYPADLTLHQPIAALVKPSGTTVSSLLVRALTQSDNTANDRLLKLVGGP +AAVRAFIERKQLGDIRFGPGERLLQAAYIADPPDGAAPLAIADALARLARGELLSETSTR +FMLTTMGSTVTGRARLKAALPPGWTLQHKTGTGQNAGFNDVGLLTAPDGRRYAIAAMIGD +TTRPMRDRQLLIQAAASALT--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F1DI10_KLEPN +------------------------------------------------------------ +------------------------------GMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELVTLASRQ +LLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGMIAALGPDGKPSRIVVINTTG +SQATMDERNR------------- +>[subseq from] Peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 n=1 Tax=Pirellula staleyi (strain ATCC 27377 / DSM 6068 / ICPB 4128) TaxID=530564 RepID=D2QYA8_PIRSD +-eKLAKRLEPIIAAHQGQVAVAIKHLPSEATF-EYRAADPMPTASLIKLPVMIEAYRQSA +AGKLDLAQSITLTEKDKVPGSGVLTKHFSAGLTLRDAIRLMMAFSDNTATNMVLERT-GI +PAVNQTMEKLDLVETKIHSQVSVLPERSKQFGLGSTTAAETVALIEKLHQGKLATPAICA +EMLQHLYATEE-ESCLPRLLPEGVRVAQKTGAVS-AVRTAAGIIESNAG-PILICVLTSE +NRTSDNSAELLIANIARETHEHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TCM1 TaxID=453246 RepID=A0A196M8N7_9SPHN +-----NVVRNLGQSFNGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD +RGKLRLTDTTTITRNDLTLHQPSAAMLKNGSTSYSDLMRRAMTQSDNTANDALLRAAGGP +EAVRGFLARRMIKDIRFGPGERLLQSNYLANPPDGAAPASIVQALAKLKEGDMLSSASSR +LLMTIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTVSIPERWALMQAVSRAVAA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. JS21-1 TaxID=1855283 RepID=A0A1H7RH27_9SPHN +---LRAEVDRLIGEFPGKAGAAIRAVDDGWTV-QRGGALSLPQQSVSKLWVAMTVLSQRD +AGKLRLDDPVLVTTNDLTLHQPIASLVRGEGTTVMGLLTRALTQSDNTANDRLLRLVGGP +SAVRAFIAEHQLGAIRFGPGERLLQSRYIDNPPDGAAPLAIADALARLARGDLLSETSTR +VMLDTMGASVTGRARLRAALPSGWTIAHKTGTGQNAGFNDVGLLTAPDGKRYAVAVMIGD +TRAPMRVRQQLIQNVAAAL---- +>[subseq from] HGE-1 beta-lactamase n=1 Tax=Azospirillum sp. CAG:239 TaxID=1262705 RepID=R6J3X4_9PROT +-nSLESRLRRIIRLSNTDAGVAVVSGSRNWAV----GNRKRPLLSVFKFFIAVQTLRQME +QTETALNAKLTVKENMTDAYSPMLKKHPRRPISLAELLEYMIAESDNNAADILLEYSGGT +GQLEKFLHDLGFSGIDIRVNEKQMNQKAENQYLNQAAPSDVAGLIKLVFEKDVLSAEHRK +FLADIMIKTSTGADKIKLGLPPGVIFGHKTGSSSRTADNDAGFVTLTNGSTYYIAVMITE +SKHDDRANAALAAQISQTVYNY- +>[subseq from] Uncharacterized protein n=1 Tax=Crocosphaera subtropica (strain ATCC 51142 / BH68) TaxID=43989 RepID=B1WW03_CROS5 +--ALKEKIQKIDAKYNVKPQAWFMDLDNGAYV-TYNGTQPVPAASTIKIPVLVAFFQEVD +KGNMHLDQMLTMTKDVMVSGSGDMQYQVDKKFPAIEVATKMIVISDNTATEMLIKQIGGK +EVLNQRFKEWGMKHTEIHNILPDLEGT------NKTSSEDLSKLLARIERGDLISTRSRD +RLIAIMEGTRT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER +AYND-PAGRSLIQDISRTVYQHf +>[subseq from] class A beta-lactamase n=1 Tax=Sphingobacterium sp. NYYP31 TaxID=2546448 RepID=UPI0012E10940 +--NLESKINAILSNYDAKVGVAINNNDFSESI-LINSEHPFPLQSTYKFHLGIVILDQVD +QGKLTLDQPISISKKSVTTYSPIKDKYPNGTLPLHEVLRYTIAESDNVGCDILFELLGGP +DFVQKYFDDQGYQDLSIKLIEEIQQANWDLQFDNWTKVKTSNKILFDYYKKQQLSEASYK +FLWDTMRSTSTGRNRIKGLLPQGTVVAHKTGYSGVNAVNDIGVVSLPNGEVFYISVYVTD +SKETEPRSAEIIAKVSKAAYDYf +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter lutipelagi TaxID=1964208 RepID=UPI0010FA4F94 +-qALDRRLSELGGTFDGQVGIAVVDIAQDASV-HYNGLQQLPQQSVTKLWVALTALDMVD +QGELDLSETVAIMRDDLTLHQPLRAQVLKQGTDFGDLLQRAIITSDNTANDRLLQRVGGP +DAVQAFLDDHELGSIRFGSDERTKQSAYLADPEDGASAVAIAQALASLSRGELLSDRSTQ +ELLGILSRTRSGPRRLKGAVPPDWAIAHKTGTGQQSGYNDIGLITSPEGKTYAVAVLIGR +TRAPNPRRMELMQRVVHAVLEY- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf33 TaxID=1736215 RepID=UPI0009E743C4 +---LTRAVETLRDNFDGLAGIAIRSVDDGWAVdSVDADRRMPQQSVSKLWVAMTVMDQID +SGRLTLDTPVTIRREDLTLHQPVASLVAKDGTNVRDLLKRAMTQSDNTANDSLLRTVGGP +AAVRSFISRKGLGNIRFGPGERLLQSRYVADPVDGAAPAAIASALARLKKGVLLSPASTR +YLVETMESSKTGKYRMRGAVPPGWTFGHKTGTGQTAGYNDVGLLIAPDGRTYAVAIMIGD +TRRPIQDRQLLMQGVVSAIVA-- +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium herbicidovorans TaxID=76947 RepID=A0A086PB28_SPHHM +------VVRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTVLDAVD +RGKFRLSDTTTITRKDLTLHQPSAGLVGSSGTSYSDLMRRAMMNSDNTANDTLLRSVGGP +EAVRSYLARRFIKDVRFGPGERLLQANYLASPPDGAAPSAIVHALAKLKEGDMLSPASSQ +LLMSIMSEAKTGPQRIKGGVPAGWRYMHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTEPIPARWELMQAVAKAVAA-- +>[subseq from] Uncharacterized protein n=1 Tax=Brevundimonas sp. Root1423 TaxID=1736462 RepID=A0A0Q7SCJ4_9CAUL +----------------------------------VNGDRPSSMQSVMKLLVGLAVLDAVE +RGELGLEDRVTLTRADVSVVQPIESRLGPSGTTIGELVRGAVIQSDSMATDWLIARLGGP +GAVQAFLERKGVTGIRLDRDERHLQTAYQQDVRDTATPRAMATLLYRLASGDLLGTSSTR +WMLATMKETQTFPDRLRAGTAPGWDAAHKTGTSNTGATNDVGVLTSPLGEPSGVAVFLAN +SPAEAPARAAAIAKVARIVTR-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9S0Q3_9BACT +--RLGAVITDVDRDLDGVLGVAIEDLTSGQRF-LLRGNEVFPQASSIKIAVLAELYRQAQ +SGKLKLNDLYTVQASDLVPDSSIMGGLTPGIVTLRDLATMMVAVSDNSATNVLIDRV-GM +ENVNGLMNSLGLANTRLRRKMMDLKAAG-EGRENISTPQDMMVLLEGLFRGKVLSKEMTD +DFFKMLSTPKS--SFIPRDLPEGLKIANKPGELE-GVRNDSGVVFLANR-PYIICVMTTY +LRR-ERDGEEAIGKISVAAYRMf +>[subseq from] Beta-lactamase n=1 Tax=Acaryochloris sp. RCC1774 TaxID=1764569 RepID=A0A2W1JBJ9_9CYAN +-----------AAQKGLTPGMYFLNADTGATL-DIAGDQAFSAASTIKVPVLLAFFQAID +AGEVNLDDKLVMRPDLIATESGTMQYQPPGTFSALETAQKMITISDNTATNMLIDLLGGA +DRLNRQFRGWGLKHTEIRNPLPDLDGT------NTISPQDLSNLMLKLSRGELLSIESRD +QTLKIMRNTVT-KTLLPRGLDSAASIAHKTGDIGS-IVGDTGLIEMPNGQRYVATVMVER +PHND-PRAQELIRKISRMTYKVf +>[subseq from] serine hydrolase n=1 Tax=Candidatus Kryptonium thompsoni TaxID=1633631 RepID=UPI000707FC99 +hkKTFEKIKFIADTSNGVIGVAVKNLETGETF-FINENLIFPQGSAIKIPILIEVIKQAS +EGKFKLTDKIKIEKKHQVGGSGVLKEFGDGTLSIYDLAVLMITVSDNTATNILIDLV-GM +ENVNKTLEKLGLKNTKLQRKMIRPDAS-ARGEENLSTPLEAMKLMEMLYKGEVISKEISN +QVIDILKKRKE--ANLNKYLPEDIQIANKPGGIE-GVTCEWGIVYLPRH-PYVIVVMSNY +NL---KSANETIAQISKIIYEHf +>[subseq from] serine hydrolase n=1 Tax=Cronobacter dublinensis TaxID=413497 RepID=UPI001319D963 +------------------------------------------------------------ +-----------------------------------------ITMSDNTAANLLLTPIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium chlorophenolicum TaxID=46429 RepID=A0A081RD19_SPHCR +-------VRSLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD +RGKIRLSDSTTITKKDLTLHQPTAALVGNSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ +LLMSIMSEAKTGPQRIKGGVPTGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTEPIPTRWQLMQAVAKAVAA-- +>[subseq from] Class A beta-lactamase n=2 Tax=Nostoc sp. 'Lobaria pulmonaria (5183) cyanobiont' TaxID=1618022 RepID=A0A2L2NVM3_9NOSO +-kALEPQIKVLMSRYSLKTGMFFLDLDTGDYL-DIGGDRVFPAASTIKLPILIAFFQDLD +AGKVTLQENLTMRRDLVTNGSGSMQERVGKKYTALETITKMITISDNTATNMIIDRLGGA +ARLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSLQSRE +QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR +PYKD-TRGRDFIRQVSQLVYNY- +>[subseq from] Putative beta-lactamase n=1 Tax=Cyanothece sp. (strain PCC 7425 / ATCC 29141) TaxID=395961 RepID=B8HLP2_CYAP4 +----EQQMNEIAARPGLTAGAFFLNLDTGAYA-DVNGAATFPAASTIKTPILVAFFQDVD +AGKIKLDERLVMRPDLIASEAGIMQYKPGTKFSALETADLMITISDNTATNMLIDRLGGA +AALNQRFLSWGLQQTVIRNWLPDLKGT------NTTSAKDLAYLMMLVGRGDLVSVRSRD +RLLDIMHRTVT-NTLLPQGLGEGAKIAHKTGDIGI-VIGDGGMVDMPSGQRYVAAAMVRR +PYND-VRGRELIQQMSRLTYQAf +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacC n=1 Tax=Planctomycetes bacterium Q31a TaxID=2527968 RepID=A0A518GCE6_9BACT +-sDLAAALQPLVDAHAGDVAVAAADLKTRISW-NYQGDQVMPTASLIKLPVMIEAYRQAQ +AGGLSLEHLIVLREEDKVPGSGILTEQFSAGLPLNDAIRLMMRYSDNTATNLVLDSI-GL +ESTAKTMAELGFPETRIHSKVFRRDTSIDSDRSGSTTANETVTLLSQLVRGELADESSTQ +SMLDHLFACEA-TNGFPRDLPAGTRVAHKTGSVTL-ARTEAGIIDSPAGK-IVLCVLTNN +NESENNAGNVLCAKLAKAAFD-- +>[subseq from] Beta-lactamase n=1 Tax=Nostoc linckia NIES-25 TaxID=1091006 RepID=A0A1Z4L226_NOSLI +--ELKTPINKLVSRYKLTPGIFFMDLETGDYI-SVNGTKAFPAASTIKYPILIALFQEVD +AGRIKLDETLVMQRKYVVGGSGSMQKRVGSKYSVLKTATMMMTISDNTATNMIIARLGGI +PKLNQRFRSWGLQSTALRRMLGDFNGT------NKTSAKDLVKLSALMVNNQLLSDKSKS +QVLGIMYGCHN-RKLLPSGLGSGAKIAHKTGTLRF-VLGDAGIIQTPSGKRYLAGIFVKR +PNND-LRARDFIRQVSQVVYGYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas edaphi TaxID=2315689 RepID=A0A418Q3M7_9SPHN +--SLAAQINAIGRGFNGIVGVSVVSLRDNWQA-DYNATRLFPQQSCSKLWVAVAAMDAVD +KGRVSLNDKVTLGRSDLTLHQPIRSKVLGGGTTLGSLLFTAITQSDNTANDKLMRSIGGP +EAVRNMIEAKNLGSIRFYDGERALQSRYIRDPYDGAAPRAVAEGLARLQKGELLSPGSTR +RLLSIMASTKTGGLRVRAALKPGWEWSHKTGTGQIGGINDIGILTAPDGTAYAMAIMTIP +NK-SDGGAQELMREVTKAVIA-- +>[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. CCH11-B1 TaxID=1768781 RepID=UPI00082A6CC1 +-----AVVRNLGQSFSGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD +RGKLRITDTTTITKNDLTLHQPSAAMLKDGMTSYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRSYLARKMIRDIRFGPGERLLQSNYLANPPDGAAPSSIVRALAKLKQNQMLSPASSR +LLMSIMSEAKTGPRRIKGGVPPGWSYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS +TTQPIPARMELMQAVSRAIAA-- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Anabaena TaxID=2619674 RepID=A0A1B7V0R2_9NOST +-----NSLQTLTANSDLIPGVFLLDLDNGGYI-DINSNISFAAASTIKIPILIAFFQDVD +EGKIRLDEMLTLQKEMIVGGSGNMQYQPTGSYTALDVATKMITISDNTATNMLVAKLGGQ +EALNGRFRSWGLITTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNMVSMRSRD +LILNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR +PNND-PRAAKLISSISSAAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520IWW5_SPHSX +------------------------------------------------------------ +----------------------------------AKVLELMIIRSDNYATDQILATLGGP +LAVQQWLSSHQMAGIRVDRNIAQLLRGHLADIKDVATPVAMVALLSRLDSGTVLTAQSRS +FLFGLMSRCATGTRRIRALLPAGTPVEDKTGTLD-GVTNDVGFITMPDGRRVALAVFARG +GR----DRQPVIAEVARAIYDRf +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter vulgaris TaxID=291985 RepID=UPI00136F84A7 +-nALEQRISQLADGSRGRIGVYAIDLSTGQEI-GILADQRFPMASTSKVAIAATYLAGVD +AGKWSLTSEWRLPR-------------PGGALSARQHIDLMISKSCNDCTDALLAAVGGP +RAVNQWMRNAGLEEFELTRDIATLIRASSVDLRDSATPRAMGQLLAGIYQGKWLSTSSRN +VLMNAMRATTTGKKRMRSALPTGAGLAHKTGTLSR-TASDIGIFHTPDGRAIAAAIYVTG +QSPSMAVE--------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas glacialis TaxID=658225 RepID=A0A502FU42_9SPHN +--ALATSVAILARQFDGRVGIAVRSIDRGWSV-DAGGEQRLPQQSVSKLWVAMTVLDYRD +RGRLRLTDPVTLYRDDITLHQPIAGLIKGDQTTVGELLQRALTMSDNTANDRLLRYVGGP +NSVRDFIQRKGLGDIRFGPGERLLQSRYVADPPDGAAPVAIAGALARLKRGDLLSPESTN +YLISTMESSHTGKQRMRGAVPPGWSFGHKTGTGQTAGYNDVGLLMAPDGSGYAIAIMIGD +TPRPIPARQALMQAVVASVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium zucineum TaxID=284016 RepID=A0A227JQW0_9CAUL +--KLQQTLDALAENFGETVGIAIVDTSSNWIV-DVRGDMAFPQQSVSKLWVALTTLDAVD +RGVVALDQQVVLTEADRSVNQPISYRITPDGTTVADLLKRALIESDNAANDKLMGMAGGP +GAVRRLMNDKGLAGISLAEDERHLQAAYLTHPYDGAQPKALAIALAQLQAGKLLSSGSTR +WMVETMAKARTGPSRLKGGLPAGWHIAHKTGTGQRGGINDVGLITAPDGKTYAVAVFLQR +TRRPVSERLAFLQSVSRAIVAQw +>[subseq from] Carboxylesterase n=1 Tax=Synechococcus sp. 60AY4M2 TaxID=1353262 RepID=A0A2G8PCC0_9SYNE +--ALQERLAALADQPGLTAGALFWEVESGAFA-GVRPDQVFPAASVIKIPILLAFLQAVE +TGQVRLDERLTLREDLRGGGAGVLQTRPLGSVSALEAATLMSTISDNFAANLIIDRLGGQ +EALNQKFRQWGLQHTQISWWLPDLEGT------NTSSPRDMVWLLSQVEQGRMLSRRSRD +RFLDILWRTQR-PSYFRPNLGQEVRIAHKTGTLRS-VVGDAGILDLPNGRRYVAAVWVKR +ETPNDPKAEELIAKLSQAAYEFw +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00142E390C +---------------------------------------------TSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAMPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLP--------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingobacterium sp. 1.A.4 TaxID=2044603 RepID=UPI000C0BBC57 +--KLQPKIDSILSKYDAKVGVAIHNHDLSDSL-IVNGDHHYPLQSVYKFHLGIVILDQVD +KGKLKMKDPLVFSKETMNSYSPIKDAHPNGVMPLDEVLFHTIAESDNIGCDAMFDLLGGP +KVVDTYFKKLGFKDQNIGYTERVQQAKWDIQFENWTTVSAGNHIMHAFYTNDLLSKKSYD +FLWDNMRKTTTGPNRIKGLLPKGTIVAHKTGTSGRNAINDIGVVSLPDGKVFYISVYVTD +SNEVGEPNERVVAEVSKAAYDAf +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas sp. OK281 TaxID=1881067 RepID=A0A1I5EBK6_9SPHN +----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD +QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYGIAVMIGD +TVRPMPERQKLIQAAAAAVANY- +>[subseq from] Uncharacterized protein n=1 Tax=Alkalinema sp. CACIAM 70d TaxID=1934309 RepID=A0A251WAN5_9CYAN +--TLKAQIQSVLAQNKLTAGVMLADLDTQAYV-DINASETFAAASTIKFPVLVAFFQEVD +AGRATLNEMLTMTKELVADEAGEMQQPVGTKFSAIKTVTDMMMISDNTATNLIINRVGGA +AALNQRFASWGLTSTQIRNWLPDVKGT------NTTSPKDMATLFALVNEGKLVSMKSRD +RILDIMRKSQA-HSLLPKGLGEGASIAHKTGTIGE-LLGDVGLIDTANGNRYVAAVLVKR +PR-DDDRAETLIQQISKLSYQMf +>[subseq from] Serine hydrolase n=2 Tax=unclassified Planktothrix TaxID=2648599 RepID=A0A3C1RY73_9CYAN +--DLKTAIMGLAKDSKLKPGVFLVDLDTGNYV-DIQGEEALPAASTIKVPILVSFFQAVD +EGRLRLDEVLTMAEKHIAKGSGELQDQPGSKFTALETVTLMIENSDNTATNMLIDRLGGI +ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSAKDLVNLMAEINQGKLISLKSRD +LMLRIMEQTRN-RSLLPSGLGEGAFIAHKTGNIDS-VSGDIGLIDMPNGKRYSVGVLVQR +EAN-DPQAPELIRQISSTIYQYf +>[subseq from] Beta-lactamase CARB-6 n=1 Tax=Leptolyngbya sp. O-77 TaxID=1080068 RepID=A0A110AW57_9CYAN +---LTTTLQSLVAQTGLSAGVFVVDLDTGDYV-DLNGSTVYPAASTIKTPILVAFLQDVD +RQRVRLDESLTLQTIDITDGSGEIQMEVGSQLSALDTATKMITISDNTATNMVIHKLGGL +TALNSRFRDWGMSHTVLNNLLADLQGT------NTTSARDLSLLLTAVSQGDLLSLRSRD +RLLDIMRSTVN-NNLLAATLGPDAKIAHKTGNIDS-LSGDSGIVDMPNGKRYVITALVQR +AG-DAGSAAQLIQQISQATYQYf +>[subseq from] Beta-lactamase n=2 Tax=Microcoleaceae TaxID=1892252 RepID=B5W7Y4_LIMMA +--DLKTQLELVAAASDITPALMFLDLNTGGYV-GLREQSKVPAASTIKVPILVAFFQAVD +AGEIRLDEMLVMTENHQVGEAGIMQYQPPGTYTALATATKMMTISDNTATNMIIERLGGF +QVLNQKFRSWGLTDTLVRNPLPDIEGT------NQTTPRDMVSLLSQIHQGGLLSMTSRD +RLLRIMTETEN-NHLLPSGVSNGAVVAHKTGTLNI-MLADVGIVDMPNGKRYILAILAQR +NNGD-QAAESMIQKMSRQVYQY- +>[subseq from] serine hydrolase n=1 Tax=Arthrospira sp. TJSD092 TaxID=2153484 RepID=UPI000D3A1865 +--DLKTQLELVAAASDITPALMFLDLNTGGYV-GLREQSKVPAASTIKVPILVAFFQAVD +AGEIRLDEMLVMTENHQVGEAGIMQYQPPGTYTALATATKMMTISDNTATNMIIERLGGF +QVLNQKFRSWGLTDTLVRNPLPDIEGT------NQTTPRDMVSLLSQIHQGGLLSMTSRD +RLLRIMTETEN-NHLLPSGVSNGAVVAHKTGTLNI-MLADVGIVDMPNGKRYILAILAQR +NNGD-QAAESMIQKMSRQVYQY- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A3D1N2I1_9BACT +--NMTASLESASSAYRGHVGIYLKDLHTGKTW-QYNPDRLFPSASLIKLPIMAAVFEKIK +AGELTLDTQITLSRQNRWGGSGSLKWVRDGTLSVMEILYKMITESDNTATRMFIDHM-GL +DFLQQEFSRLGLLYTKIYPEGLSLSSG-RVRRENYTTAREMAGILERIYDGELISRDSSE +QMLEVLKHNKS-RNRLRRGLPIGWEIGHKTGLLRR-SCHDVGIIFSPRGD-YIIAVLTSN +VP-NYSSAKNFISMVAKLTYKYy +>[subseq from] Beta-lactamase n=2 Tax=Microcoleaceae TaxID=1892252 RepID=K1X8H1_ARTPT +--DLKTQLELVAAASDITPALMFLDLNTGGYV-GLREQSKVPAASTIKVPILVAFFQAVD +AGEIRLDEMLVMTENHQVGEAGIMQYQPPGTYTALATATKMMTISDNTATNMIIERLGGF +QVLNQKFRSWGLTDTLVRNPLPDIEGT------NQTTPRDMVSLLSQIHQGGLLSMTSRD +RLLRIMTETEN-NHLLPSGVSNGAVVAHKTGTLNI-MLADVGIVDMPNGKRYILAILAQR +NNGD-QAAESMIQKMSRQVYQY- +>[subseq from] serine hydrolase n=1 Tax=Sphingobium phenoxybenzoativorans TaxID=1592790 RepID=UPI0009F212AF +----VSIIQSLGRGFNGHAGIAVKRVDADWVV-SYNGNELFPQQSVSKLWVAMNLLDNVD +RGKLKLTDSVTLGRSDLTVHQPLAAMIGKDGTTYADLFRRAMTQSDNTANDAMLRRSGGP +DAVRGFLARRFISNIRFGPGERLLQSDYLANPPDGAAPIGIVTALAKLKKGDMLSPTSTR +FLLDTMHEAKTGPQRIKGGVPAGWTYAHKTGTGQSTGFNDVGIMTAPDGTSYAVAVMIGS +TTVSIPERWALMQGVARAIAA-- +>[subseq from] Serine hydrolase n=1 Tax=Calothrix sp. HK-06 TaxID=1137096 RepID=A0A1Q4RY28_9CYAN +--SLKSAIQNLAIQNNLTPGVFIADLDNGGYV-DFNGGAMFSSASTIKLPILMAFFQEVD +EGKINLEETLRTSKSTVAGGSGDMQNRPGTQYGILEVATKMMTISDNTATNMLIERMGGI +EKLNQRFRSWGLNTTSLGNILPDIEGT------NKTSPKELSNLMAMITKGNIVSSQSRE +RIIDIMQRTVK-DTLLPVGLGQGAKIAHKTGEIG-GMLADTGLVELPSGKRYLISVMVQR +PRND-VSAEKLINGISRAAYQQf +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. SAORIC-644 TaxID=1869314 RepID=A0A2K1E876_9SPHN +-rELDREISRIGGTFPGHVGIAVRDIAARRTL-HFNGLQLFPQQSVSKLWVTLTALGEVD +AGELELTEKVEIRDPDLTVHQPIREIVRRRGTDYADLIERAITHSDNTANDRILRRVGGP +DVVQKFLDDHGLSSIRFGTDERTKQSAYLADPIDGAPPVAIVEALARLHEGKLLSGPSTA +LLLATMSRTKSGPQRLKAGAPQDWIVRHKTGTGQQSGYNDIGLFTSPDGRTYAIAVMIAR +TRVSIPERMAMMQEVVRAVVNY- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas carotinifaciens TaxID=1166323 RepID=A0A1G7N6V5_9SPHN +-----RTVQSLYAGFEGKKGIAIRAVDDGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD +KGKARLDDPITVRREDLTLHQPIAYLVKGDGTTVGGLLTRALTQSDNTANDRLLTYVGGP +AAVRRMIAEKRLGDIRFGPGERLLQAAYVADPPDGAAPIAIADALARLTRGELLSETSTR +ILLETMGASRTGHARLRAAVPASWQIAHKTGTGQNAGFNDVGLLTAPDGRRFAVAVMIGD +TTEPIRNRQVLIQNVAAAVAT-- +>[subseq from] serine hydrolase n=1 Tax=Nostoc sp. PA-18-2419 TaxID=2575443 RepID=UPI0011082C93 +-------INKLITRYKLTPGIFFMDLETGDYI-SINGNKAFPAASTIKYPILIALFQEVD +AGRIKLNETLVMQRRYVVGGSGNMQQRVGSKFSVLKTATMMMTISDNTATNMIIARLGGI +AKLNQRFRSWGLQSTALQRMLGDFNGT------NKTSAKDLVRLSALMVNNQLLSAQSKS +QVIGIMYGCHN-RRLLPSGLGYGAKIAHKTGTLRF-VLGDAGIIETPSGKRYYAGIFVRR +PNND-DRARDFIRQVSQVVYGYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9ZM42_9BACT +-qKLEATIHETDQSLDGAMGVAILDLSTGQKF-LLHHDDVFPQASSIKITVLAELYRQAQ +QDKLKLTDLYTVQASDLVPDSDIMNGLTPGVITLRDLATMMVAVSDNSATNVLIDRL-GI +ENVNAFLDSLGLTHTRLRRKMMDLKAAG-EGRENIATPREMMVLLEALYRGKVLNKEMTD +DFFKMLSTHK--DSWMPRDLPEDTRVANKPGSLE-GVRNDSGIVFAKNR-PFVICVMTT- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=unclassified Synechococcus TaxID=2626047 RepID=UPI000C19D722 +--ALQERLAALADQPGLTAGALFWEVESGAFA-GVRPDQVFPAASVIKIPILLAFLQAVE +TGQVRLDERLTLREDLRGGGAGVLQTRPLGSVSALEAATLMSTISDNFAANLIIDRLGGQ +EALNQKFRQWGLQHTQISWWLPDLEGT------NTSSPRDMVWLLSQVEQGRMLSRRSRD +RFLDILWRTQR-PSYFRPNLGQEVRIAHKTGTLRS-VVGDAGILDLPNGRRYVAAVWVKR +ETPNDPKAEELIAKLSQAAYEFw +>[subseq from] Serine hydrolase n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A353GXF9_9FIRM +---------QAVDFKKMNCAFIITNLRNGESA-SYNQEERVPSASLIKLPVMAETVRQVK +EGRLHLQDRVTVKAEDKVPFSILTMLETENNYSLQDLLTLMIVQSDNTAANILIQRV-GM +AKINDFCIDLKMRNTLLERQMMDLNAR-RAGRENRTTASDMARFLERLYQGELIDKASST +YMIEIMKKQLE-NSMMRLYIPDETVIAHKSGELD-GIAHEAGIVYHEKGD-FLFVVLVWN +AV-TNNEARQTIGQISKIAYDYf +>[subseq from] Beta-lactamase family protein n=2 Tax=Sphingobium sp. RAC03 TaxID=1843368 RepID=A0A1B3MR00_9SPHN +--TLVSAIRNLGQGFRGKVGIAVRRIDADWTV-AWNGTALFPQQSVSKFWVALTFLDAVD +RGKLRLTDTTTITKNDLTLHQPSAAMVKAGGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRSYLARRMIKDVRFGPGERLLQANYLANPPDGAAPTAIVGALAKLKQGDMLSAESTR +LLLTVMAEAKTGPQRIKGGVPLGWSYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVLIGS +TTVSIPERWALMQGVAKAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingobacterium cellulitidis TaxID=1768011 RepID=UPI000B942B89 +htDLKKQIDEILNSYDAKAGIAIHNHDFSDSL-IINGNHKYPLQSTYKFHLGIAILDQVD +KGKLSLDQPVEFSKEMLKTYSPIKDKYPNGVLPLSEVMRYTIAESDNIGCDAMFELLAGP +DKVQEYFVEKGYTEQSIKTNEAVQQADWDIQFQNWTKVSQANKILFDYYTKNLLSESSHK +FLWDTMRSTSTGKNRIKGLLPKGTTVAHKTGYSGTAAVNDIGVISLPNGQVLYISVYVTD +SKETEPQSASIIAKVSKAAFDYf +>[subseq from] Uncharacterized protein n=1 Tax=Roseofilum reptotaenium AO1-A TaxID=1925591 RepID=A0A1L9QXD5_9CYAN +--ALKNQIQALASQSEFKPGVFVLDLDTAGYV-DMQGTLAFSSASTIKLPILLAFFQAVD +AGTIRLDETLTLKEVHRAGGSGSLQYPVGSEYTALEVATWMMTISDNTATNIIIERLGGM +VQVNQSFSRWGLQQTVLRDWLPDLDGK------NTTSPRELAQVMAMIHQGDVVSLKSRD +RMIDIMRQTET-SVLLEQGLGAGATIAHKTGDIGK-LLGDVGLIDLPSGKRYIAAVLVER +PHND-YGAANLIGDISHLAYEH- +>[subseq from] serine hydrolase n=1 Tax=Myxacorys almedinensis TaxID=2651157 RepID=UPI0013920E67 +----------------LTPGVMVVDLDTHTFL-DINASNSFAAASTIKVPVLAAFFQEVD +AGKIRLDEMLTMRPDLIATEAGDLQYQPPGSFLALEVVTKMITVSDNTATNMIIDRLGGK +DALNQRFQTWGLTHTAIRNPLPDLGGT------NTTSPKDMATLMSMINSGQMVSSRSQA +RMLDMMRNVVT-DSLLPRGLGEGATIAHKTGDIGS-LVGDIGMVDMPSGKRYVIGVLVKR +PHND-DNAQNLIRQISTLTYQYf +>[subseq from] Class A beta-lactamase n=1 Tax=Psychromonas sp. RZ22 TaxID=2555643 RepID=A0A4Y8A114_9GAMM +------------------------------------------------------------ +-----------IEEESILGYAPITSHKIGQTMSLSELCEAAMFVSDNTAANLLLKELGGP +STITVFMKILGDNTTRLDRWEPELNEATVNDIRDTTTANAMTESLYSVLFQEHLSELSRQ +QLQYWLINNKVTGSLLRSVIPQSWSIGDRSGAGGSGSRGITAVIFPDNQPAVFVAIYITQ +TKASMAQRDRAIAEIGEVIF--- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=unclassified Apibacter TaxID=2630820 RepID=UPI00135D8A41 +-qSLEKKIHSITKNKKATVGVAVI-FDGKDTL-TVNNDMEYPAMSVFKFHQALALLDYMN +KNLLSLESNLYLKKSDIKKYSPLAKEYPEGNIPIGDLLNYTVSKSDNNASDALYYYMSGT +KMTDLYLRTLGSKNFSIQATEEEMSKDFNNQYINWTTPLEAARLLDIFMNKDIFCKNYKD +FLFQAMTESEPGSDKLKALLPKKVLIGHKSGSSSRNADNDIGFVYLPNGKQYSIAVFIKD +SKEDDKTNARMIADISQVVYNFy +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium sp. EP60837 TaxID=1855519 RepID=A0A173KUC9_9SPHN +------VVRNLGQSFNGKVGIAVRRIGSDWTV-AWNGSALFPQQSVSKLWVSMTFLDAVD +RGKIRLSDTTTITRKDLTLHQPTAALVGNSGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRSYLARRYIKDIRFGPGERLLQANYLASPPDGAAPSSIVNALAKLKEGSMLSPASAQ +LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDVGIMTAPDGTSYAVAVMIGS +TTEPIPTRWQLMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9WGK0_9BACT +-qKLEAATRDLDAQLDGVMGVAIEDLTTGNHI-FLHADEVLAQASSIKITVLAELYRQAQ +QGKLKLTDLYTVQASDLVPDSDIMGGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GM +DNVIAMLDSLNLPHTRLRRKMMDLEAA-KHGRENISTPREMMILLEDIYQGKVLNQEMTA +DFFKLLSTNKS--SWIPRDLPAGVKVANKPGALE-GVRNDSGIVFVEGR-PYVICVMTTF +LR-NERDGEEAISKISLAAFRMf +>[subseq from] Carboxylesterase, beta-lactamase family n=1 Tax=Synechococcus sp. (strain JA-3-3Ab) TaxID=321327 RepID=Q2JW55_SYNJA +--ALQERLAALADQPGLTAGALFWEVESGAFA-GVRPDQVFPAASVIKIPILLAFLQAVE +TGQVRLDERLTLREDLRGGGAGVLQTRPLGSVSALEAATLMSTISDNFAANLIIDRLGGR +EALNQKFRQWGLQHTQISWWLPDLEGT------NTSSPRDMVWLLSQVEQGRMLSRRSRD +RFLDILWRTQR-PSYFRPNLGQEVRIAHKTGTLRS-VVGDAGILDLPNGRRYVAAVWVKR +ETPNDPKAEELIAKLSQAAYEFw +>[subseq from] serine hydrolase n=1 Tax=unclassified Phenylobacterium TaxID=2640670 RepID=UPI00083AFFBC +--ALQARLDELAAAYGEEVGVAVTDVAEGWTA-GVDHERPYPQQSVSKLWVAIAVMKAAD +EGRLDPYGWVTLTGEDRSVYQPVSYRIGTGGTPISDLLRRALVESDNAANDKLMRELGGP +DGVAATLEGMGLTGVKVGAYERDLQAAYLAQPLDGAAPGEITTALAALSRGELLSPRSTE +WLIGLMTQARTGPRRLKGGLPAGWTIAHKTGTGQSVGINDVGLITAPDGHVYAVAVMMRR +TRKPVPERLAFMQSVTRAVAEQw +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=A0A0K9YPH9_9BACL +--DLQKKIEELVGQATATFGIVIKHLETNEEV-KINEGHLFQMASCYKVPILATLFREVE +AGTIDLNTRVRLSLTDRVPGSGVLKEFDPGSVSLKDLATLMIIVSDNVGTDKILELV-GV +NRTDQYMKSIGLQDTYVNLTCWQLLSFTKSIENNVSTPADMALLLEKIARKELISKNACE +QMIDIMKRQHF-RDRIPNLLPAGTPVACKSGSVGS-VHNDIGIIYLPEEKGTVIVSAFSE +NNSSQLEAAQMIAKVAQSAYDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter junii TaxID=40215 RepID=S5ZYH8_ACIJU +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDE---------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. AP23 TaxID=499656 RepID=UPI0009F9E9C7 +-qRLDRELSRIGSTFAGHAGIAVRDMEARRTL-HFNGLEAFPQQSVSKLWVAMTALDEVD +EKRLDLTERVEIRARDLTVYQPIRDIVRRDGSDYADLIERAIAESDNTANDRILRRIGGP +EAVQDFLDGHGLSSIRFGTDERSKQSTYLADPVDGAPPVAIVEALARLYRGNLLSNSSTS +LLLGALSRTKSGPQRLKAGAPEDWLVRHKTGTGQQSGYNDVGLVTSPEGRSYAIAVMIAR +TREPTPLRMEMMQEVVRAVAR-- +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingobacterium sp. CZ-2 TaxID=2557994 RepID=A0A4P7DU00_9SPHI +--KLQPKIDSILSKYDAKVGVAIHNHDLSDSL-IVNGDHRYPLQSVYKFHLGIVILDQVD +KGKLKMKEPLVFSKETMNSYSPIKDAHPNGVLPLDEVLFHTIAESDNIGCDAMFDLVGGP +KVVDTYFKKLGFKDQNIAYKERVQQAKWDIQFENWTTVSAGNHIMHAFYTNDLLSKKSYD +FLWDNMRKTTTGPKRIKGLLPKGTVVAHKTGTSGTAAINDIGVVSLPDGKVFYISVYVTA +SNEVGEPNERVVAEVSKAAYDAf +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5SRK3_9BACT +------------------------------------------------------------ +-------------------------------MTLGALCEAAIEQSDNTAANLLLDAVGGP +ASLTYFARKLGDQITRLDRKEPDLNSAIAGDERDTTTPGAMCLDMQRLLVASVLSESSRR +QLEDSLLRNKMGQLMIRAGVPKTWSVGDKSGRCANGATNDIAIIRPPDRAPILLAIYSVG +STAPANNREMAIAEVAKIVAELf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas oleivorans TaxID=1735121 RepID=A0A2T5FYC2_9SPHN +---LDSAITALGSGFNGTVGIAVRDVQAGWTV-AYNGGLAFPQQSVSKLWVAITLLDAVD +RGELSLDEQLLIGPRDFTVHQPIRALVGAGGTSYRSLLSLAMTQSDNTANDLLLRRAGGP +DAVRAMFLRKGLAGIAFGPGERLLQSRYLADPMDGAQPVGIVAALSRLRRGELLSIASTH +YLLGLMSSSRTGPQRLRGGLSPDWSFAHKTGTGQATGYNDVGLLTSPDGRSYAVAVMIGS +TRRGIPERQRLMQDVTRAVIA-- +>[subseq from] serine hydrolase n=1 Tax=Geitlerinema sp. PCC 9228 TaxID=111611 RepID=UPI000AC105E1 +--SLKSQWKEIVSNYRFDVGAFLLDLDTGAYI-NLNSKASYSAASTIKVPILIAFMQEVD +AGNIQLQEKLEMKEKHVAGGSGNLQQQVGTQYTAWELASKTIAISDNTATNILIDRLGGI +EKLNQRFQSWGLQTTRLRNPLPDLEGT------NTTNPQELAKLMAWIEQGHMLTLRSRD +RLLHLMRQTEN-DSLLPQGLPSQASIAHKTGDIGS-LLADVGTIDLPNGKRYLLAVMVKR +PHNN-YVAADIIRKISQTTA--- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2W0AK43_9BACT +-qKLEAGIGEVDRDLDGVLGLAILDLSSGQKF-LLHPDDVFPQASSIKIAVLAELYRQAQ +QGKLKLTDLYTVEASDLVPDSDILGGLTPGVITNRDLATMVVAVSDNSATNVLIDRV-GM +ENVNALMDSLGLTHTRLRRKMMDVKAA-GEGRENVSTPREMMALLESIYRGEVLNKEMTD +DFLKMLSTHKE--SFLPRDLPDDVRVANKPGELE-AVRNDSGIVFAKNR-PYVICAMTTY +LR-NERGGEQAITKISALAYRMf +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sp. EC-SD391 TaxID=2038398 RepID=A0A5E8ACG3_9SPHN +--SLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD +QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGS +AAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TIRPMPERQKLIQNAAAAVANY- +>[subseq from] serine hydrolase n=1 Tax=unclassified Synechococcus TaxID=2626047 RepID=UPI0002D43228 +--ALQERLAALADQPGLTAGALFWEVESGAFA-GVRPDQVFPAASVIKIPILLAFLQAVE +TGQVRLDERLTLREDLRGGGAGVLQTRPLGSVSALEAATLMSTISDNFAANLIIDRLGGR +EALNQKFRQWGLQHTQISWWLPDLEGT------NTSSPRDMVWLLSQVEQGRMLSRRSRD +RFLDILWRTQR-PSYFRPNLGQEVRIAHKTGTLRS-VVGDAGILDLPNGRRYVAAVWVKR +ETPNDPKAEELIAKLSQAAYEFw +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas aurantiaca TaxID=185949 RepID=A0A2T5GME3_9SPHN +--SLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD +QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGS +AAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TIRPMPERQKLIQNAAAAVANY- +>[subseq from] serine hydrolase n=1 Tax=Sciscionella sp. SE31 TaxID=1445613 RepID=UPI00068B861E +---LRARLAAIAHTTKAEVGVSVQNLAAGQRI-EIGARTRMPSASVIKLPILAELLRMAE +RGELSLAERVHVDRSDVVGGTGQLQEKLPQDISLHRLARYMIIYSDNTATNLLIDRI-GF +GPVNALIRSLGLRSTVLERKMMDTEAQ-QHGRENYLDAADIAKLLRSLWDGRLLSAPSRA +IALGFLRDQRL-NELIPAALPPGAPVAHKTGTLDDLVTHDVGYYLVPGSE--VLVVFTTK +GT--TAAGTAAVHRMARAVWD-- +>[subseq from] Beta-lactamase n=2 Tax=Crocosphaera watsonii TaxID=263511 RepID=T2JS57_CROWT +--ALQEKIQKIDAKYNVKPQAWFIDLDNGAYV-TYNGTQPIPAASTIKIPVLVAFFEEVD +KGNIHLDQMLTMTKDVMVSGSGDMQYGINKKFTALEVARKMIVISDNTATEMLVKQMGGK +EVLNKRFKEWGMKNTEINNILPDLEGT------NKTSSEDLSKLLARIERGDLISARSRD +RLIDIMEGTRT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER +AYND-VAGRHLIQDISRTVYQHf +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Luteibacter TaxID=2620188 RepID=UPI00068BE602 +--TLQASLQKLADQAPAKFGIIVVDLDGSASA-KVNDDRAYMLMSTFKAPVSAAVLSQVD +AGKLSLNQKVHVTPADVTAGSPSIGARAAKGVTVSELMTAAATQSDNTAVDALLKLVGGG +QVVTAYLKDKGVEGMRIDMDERAVGHAAIVMQENTTTLDGAATFLRKLQAGELLSAASTK +RLLDMMQAQVI-PNRIRAGLPAGFSIADKTGTGASNAWNDMAIITAPNGNRAVVGAFLRD +TTSTDEQRAAWFKELGTVVSK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas faeni TaxID=185950 RepID=A0A2T5U7L4_9SPHN +----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD +QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYGIAVMIGD +TIRPMPERQKLIQAAAAAVANY- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9HM46_9BACT +-qKLEAMIGGVDRNLDGVLGVAILDLTTGQNY-LLHADEVLPTASSIKIAILAELYHQAQ +QGKIKLGDLYTLQSADLVGGSGVAGALTPGVLTLRDVAALMISVSDNSATNIIIDRI-GM +ENVNALLDSLGLTHTRLRRKMMDVKAA-AEGRENIATPREMMLLLENLYRGKVLNKQFTE +EFFNLLSIHKE--SYIPRELPEDLRVANKPGELE-GVRNDSGIVFAGKR-PYVISVMTTY +LRRE-HDGGEAIMRISNAAYQMf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus antibioticus TaxID=2570228 RepID=A0A4U2Y5J9_9BACL +--DLQKKIEELVGQATATFGIVIKHLETDEEV-KINEGHLFQMASCYKVPILATLFREVE +ARAIDLNTRVRLSLTDRVPGSGILKEFDPGSVSLKDLATLMIIVSDNVGTDKILELV-GV +NRTDQYMKSIGLQDTHVNLTCWQLLSFTKSIENNVSTPADMAFLLEKIARKELISKKACE +QMIDIMKRQHF-RDRIPNLLPAGTTVACKSGSVG-GVHNDIGIIYLPEEKGTVIVSAFSE +NNSSQLEAAHMIARVAKTAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2E3HJW8_9SPHN +--ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD +AGRLDLGEMVRIRPGDLTVHQPIRDIVRRDGADYAELVXRAITQSDNTANDRILRRVGGP +AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS +LXLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR +TREPTPVRMEMMQEVVRAVVRY- +>[subseq from] Serine hydrolase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A0J9D3E3_SPHYA +---LVSVIQNLGQSFRGKVGIAVRRVGADWTV-AYNGNALFPQQSVSKLWVSMTFLDAVD +RGKIRLADSTTITKKDLTLHQPSAAMVGSGGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVEALAKLKEGDMLSSASSR +LLMSTMEEAKTGPQRIKGGVPHSWTYMHKTGTGQSTGFNDVGIMTAPDGTSYAVAVMIGS +TTVSIPERWQLMQAVARAVVA-- +>[subseq from] serine hydrolase n=1 Tax=Arthrospira sp. TJSD091 TaxID=1640536 RepID=UPI00061B4ADC +--DLKTQLELVAAASDITPALMFLDLNTGGYV-GLREQSKVPAASTIKVPILVAFFQAVD +AGEIRLDEMLVMTENHQVGEAGIMQYQPPGTYTALATATKMMTISDNTATNMIIERLGGF +QVLNQKFRSWGLTDTLVRNPLPDIEGT------NQTTPRDMVSLLSQIHQGGLLSMTSRD +RLLRIMTETEN-NHLLPSGVSNGAVVAHKTGTLNI-MLADVGIVDMPNGKRYILAILAQR +NNGD-TAAESMIQKMSRQVYQY- +>[subseq from] Uncharacterized protein n=1 Tax=Limnospira indica PCC 8005 TaxID=376219 RepID=H1WII0_9CYAN +--DLKTQLELVAAASDITPALMFLDLNTGGYV-GLREQSKVPAASTIKVPILVAFFQAVD +AGEIRLDEMLVMTENHQVGEAGIMQYQPPGTYTALATATKMMTISDNTATNMIIERLGGF +QVLNQKFRSWGLTDTLVRNPLPDIEGT------NQTTPRDMVSLLSQIHQGGLLSMTSRD +RLLRIMTETEN-NHLLPSGVSNGAVVAHKTGTLNI-MLADVGIVDMPNGKRYILAILAQR +NNGD-TAAESMIQKMSRQVYQY- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9ALL3_9BACT +-qKLAATIKEVDGKLDGVLAVAILDLSTDQKY-LLHADEAMPTASSIKIAILAELYRQAQ +QGKVKLTDFYTLQRSDMVGGSGITRVLTPGMLTLRDVAGLMISVSDNSATNVVIDRI-GM +ENVNALLDSLGLTHTRLRRKMMDLEAA-SEGRENFATPREMALLLENLYRGKVLDQQMTD +DFFNLLSVHKE--SYIPRNLPEDLKVANKPGELE-GVRNDSGIVFTGKR-PYVISVMTAY +LRRE-RDGGDAIAKISDAAYLMf +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. JBTF-M21 TaxID=2584124 RepID=A0A547PC00_9SPHN +--AFERQIVQLADGDQGRIGVYAIDLETGKEI-SVLGDQRFPMASTSKVAVAAAFLDGVD +QGKWKLSDEFPLMIPVKSAKFSTSRAPVRTGVAAWELISLMISKSCNSCTDALLRVVGGP +KAVNAWMRDAGFDDFELSRDIATLVRVEWIDPRDSASPRTMGLLIAGIYQGRWLSQQSRG +LLMAALEETTTGRRRMTAALPESARLAHKTGTLSR-TASDIGIFRLPDGRAVAAAIYVTG +QSANRKKRDERIAAITRALYNGf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8YV12_9BACT +-qKLAAAVNEVDSKLDGVLGVAILDLTTGQKY-LLHPDELMPTASSIKIAILAELYRQSE +QGKVKLTDFYTLQQSDMVGGSGITSVLTPGMLTLRDVAGLMVSVSDNSATNVIIDRI-GL +ENVNALLDSLGLTHTRLRRKMMDLKAA-SEGRENLATPREMMLLLENLYRGKVLNKQMTE +DFFNLLSVHKE--SYIPRDLPEAIKVANKPGELE-GVRNDSGIVFAGKR-PYVISVMTTY +LKRE-RDGGDAITKISDAAYQMf +>[subseq from] serine hydrolase n=1 Tax=Limnospira indica TaxID=147322 RepID=UPI0012FA23D2 +--DLKTQLELVAAASDITPALMFLDLNTGGYV-GLREQSKVPAASTIKVPILVAFFQAVD +AGEIRLDEMLVMTENHQVGEAGIMQYQPPGTYTALATATKMMTISDNTATNMIIERLGGF +QVLNQKFRSWGLTDTLVRNPLPDIEGT------NQTTPRDMVSLLSQIHQGGLLSMTSRD +RLLRIMTETEN-NHLLPSGVSNGAVVAHKTGTLNI-MLADVGIVDMPNGKRYILAILAQR +NNGD-TAAESMIQKMSRQVYQY- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A2D8MGN0_9SPHN +--ALQQQLRDLGETFNGDVGIAVTQADTLATM-SYSGKKRFPQQSVSKLWVSLTALDLRD +EGALDLSEPVRLRAEDLTVHQPLRNIVRARGTDYADLINRAITQSDNTANDRLLRRVGGP +SAVEGFLRRNQISGVQFGTDERTKQSAYLADPIDGASPVGITKALARLARGDLLSENSTD +LIVSTMQRTRSGPRRLKGGVPAGWTIAHKTGTGQQSGYNDIGILTAPDGTNYTMAVMIGS +TRASYAARMGMMQEVTRSVVRY- +>[subseq from] Beta-lactamase class A n=1 Tax=Propionispora vibrioides TaxID=112903 RepID=A0A1H8PNC5_9FIRM +-kQLEQTIQQILTTCPCQQALLIRHLPSGRQF-ALNPDQVFPAASMIKLPIMYEVMRQAS +QGRLALEELLEVTEAVRVGGAGILQERPGIALTVQELVTLMIVISDNTATNLLLNRI-GL +AAVNSTAEQLGLTNTVLRRRMMDFTAA-RAGQENHTSVADIAKLLEIMYQQTTLPPEYGE +LMLNILKRQQI-RDKLPFYLPEDIAIAHKTGTLD-GVEHDAGILFSAGG-PYLISVMTAD +LPVN-YQGLQLVAQIGRAIFEY- +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. CAG:144 TaxID=1262736 RepID=R5YBD0_9BACE +--DIQLAIHSVINDKRATVGIAIL-CDDGNMV-VMNDDERYPVMSVFKFHVVVTALKKME +QHGIPLDSMTLIPQEQMLSYSPLREKYPNRDISYRNIIRYTMAHSDNNTCDFLIDFVGGI +SVVDSLIRQLGINKFAFSETEKTMHENILNCYNNWCTPSSMVLFLKKIYTEPILNNDHFL +FLEQVMIETSTGTNKIKAGLPADVILGHKTGSSDRTGDNDAGIIYLPHNKRCYIAIFIKD +SKENDTANAKIIADITEKIYE-- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059XBW0_9BACT +--DLSNRLTTLAKSLGDEVALSVVHVESGRAV-AVEGAKKLQLYSVFKVPLAIAVLKAVE +EKKLSLDQKVHVTPGDVAPGSQFNTDLWRQPKSVAELLEFSIVRSDNTSSDKLLGLVGGP +AGVTQRMRALGYSDIDIVSTVRGYASK--QGNPNVGAPVDLARLLTQLQKGELIQPANAL +LLLGFMERARTGERRLRASLPPGTPVADKTGSGT-AATNDIGVITLPDSGHLAIAVLING +TKSKTEAQEKLIAEIARAAYDAf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D4Y597_9SPHN +-rELDREISRIGGTFPGHVGIAVRDIAARRTL-HFNGLQLFPQQSVSKLWVTLTALGEVD +AGQLELTEKVEIRDPDLTVHQPIRDIVRRRGTDYADLIERAITHSDNTANDRILRRVGGP +DVVQKFLDDHGLSSIRFGTDERTKQSAYLADPIDGAPPVAIVEALARLHEGKLLSGPSTA +LLLATMSRTKSGPQRLKAGAPQDWIVRHKTGTGQQSGYNDIGLFTSPDGRTYAIAVMIAR +TRVSIPERMAMMQEVVRAVVNY- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. AP49 TaxID=1144307 RepID=J2W8N5_9SPHN +---LVSVIQNLGQSFRGKVGIAVRRVNSDWTV-AYNGSALFPQQSVSKLWVSMTFLDAVD +RGKIRLSDSTTITKKDLTLHQPSAAMVGATGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVEALAKLKEGDMLSSASAR +LLMGIMEEAKTGPQRIKGGVPHSWSYLHKTGTGQSTGFNDVGIMTAPDGTSYAVAVMIGS +TTVSIPERWQLMQAVAKAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D9X7Q1_9SPHN +-rELDREISRIGGTFPGHVGIAVRDIAARRTL-HFNGLQLFPQQSVSKLWVTLTALGEVD +AGQLELTEKVEIRDPDLTVHQPIRDIVRRRGTDYADLIERAITHSDNTANDRILRRVGGP +DVVQKFLDDHGLSSIRFGTDERTKQSAYLADPIDGAPPVAIVEALARLHEGKLLSGPSTA +LLLATMSRTKSGPQRLKAGAPQDWIVRHKTGTGQQSGYNDIGLFTSPDGRTYAIAVMIAR +TRVSIPERMAMMQEVVRAVVNY- +>[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. Z007 TaxID=627495 RepID=UPI000B4A42CC +------VVRNLGQSFNGKVGIAVRRIGADWTV-AWNGTALFPQQSVSKLWVAMTFLDAVD +RGKLRITDTTTITRNDLTLHQPTAALVAKEGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRSFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNQMLSPASSR +LLLSIMAEAKTGPQRIKGGVPPGWHYLHKTGTGQSTGFNDIGIMTAPDGASYAVAVMIGS +TTVGIPERWALMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A3B9UN96_9SPHN +-rELDREISRIGGTFPGHVGIAVRDIAARRTL-HFNGLQLFPQQSVSKLWVTLTALGEVD +AGQLELTEKVEIRDPDLTVHQPIRDIVRRRGTDYADLIERAITHSDNTANDRILRRVGGP +DVVQKFLDDHGLSSIRFGTDERTKQSAYLADPIDGAPPVAIVEALARLHEGKLLSGPSTA +LLLATMSRTKSGPQRLKAGAPQDWIVRHKTGTGQQSGYNDIGLFTSPDGRTYAIAVMIAR +TRVSIPERMAMMQEVVRAVVNY- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFOXYB2_FULL_62_6 TaxID=1797970 RepID=A0A1F9ZDY1_9BACT +---MVTSLENTAYNYRGHVGIYLRDLNSGRTW-EYNADRLFPSASLIKLPIMAAVFDKIK +TGALSLDTQIKLTRRDRAGGSGSLKWVREGTLSVMEIIYKMITESDNTATKMLIDYA-GI +NYYQLTFEKLGLVYTRIYPEGLSLTSG-RVARENYTTAREMSVLLERIYRGDLVDRASSE +AMLEFLKQNK-GRTRLRKGLPIGWEIGHKTGLLRK-SCHDVGIVFSPRGD-YIIAVLTGD +VP-DYTSAKSFISKVAKLTYEYy +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Methylomusa anaerophila TaxID=1930071 RepID=A0A348AGG3_9FIRM +---LHRNIERILTAYTGRWGMVIVNQSTGARL-ELNPEMVFPAASMIKVPIMYEIMRQAA +AGTISLDDSLTVTSCFRTGGAGILKERPGLTLTVRELVTLMIILSDNTATNMLIDLA-GM +EAINKTITGLGLKSTVLRRRMMDFDAALA-GKENYTSAADLALMFANIYHSRGLPESYGA +LMMDILTRQQI-RDKLPFYLPAKTVMAHKTGTLT-GVEHDAGILFLPGG-PYIICVLTGD +LAAN-QQGIQLVASIGKVIYEYf +>[subseq from] Beta-lactamase n=1 Tax=Oxalobacteraceae bacterium TaxID=1871070 RepID=A0A4Q3L3H0_9BURK +------------------------------------------------------------ +---------------------------------AAKVMELMIIRSDNQATDQLLTTLGGP +AAVQQWLLTQKIAGIRIDRSIAQLLRDHLADSKDVATPVAMVTLLTKLDNGTILTAQSRA +FLLDLMNRCATGTRRIRALLPAGTRVENKTGTLD-GITNDVGFMTMPDGRRVAVAVFARG +GR----DRQPAIAEVARVIYNRf +>[subseq from] Beta-lactamase n=1 Tax=Crocosphaera watsonii WH 0003 TaxID=423471 RepID=G5J769_CROWT +--ALQEKIQKIDAKYNVKPQAWFIDLDNGAYV-TYNGTQPIPAASTIKIPVLVAFFEEVD +KGNIHLDQMLTMTKDVMVSGSGDMQYGINKKFTALEVARKMIVISDNTATEMLVKQMGGK +EVLNKRFKEWGMKNTEINNILPDLEGT------NKTSSEDLSKLLARIERGDLISARSRD +RLIDIMEGTRT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER +AYND-VAGRHLIQDISRTVYQHf +>[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Kryptonium thompsoni TaxID=1633631 RepID=A0A0P1LDV6_9BACT +hkKTFEKIKFIADTSNGVIGVAVKNLETGETF-FINENLIFPQGSAIKIPILIEVIKQAS +EGKFKLTDKIKIEKKHQVGGSGVLKEFGDGTLSIYDLAVLMITVSDNTATNILIDLV-GM +ENVNKTLEKLGLKNTKLQRKMIRPDAS-ARGEENLSTPLEAMKLMEMLYKGEVISKEISN +QVIDILKKRKE--ANLNKYLPEDIPIANKPGGIE-GVTCEWGIVYLPRH-PYVIVVMSNY +NL---KSANETIAQISKIIYEHf +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. YT30 TaxID=1735012 RepID=A0A125QJL3_9SPHN +--SFEQRIAELADGNLGRIGVYAVDLATGEEI-SVLGDQRFPMASTSKVAVAATFLAGVD +EGRYSLTSEYPLLIPVRSKKFSSEKAPVRTGVPAYELISLMISKSCNSCTDALLKAVGGT +EEVNKWMRQAGLSDFELSRDIATLVRVEWIDPRDSATPRVMGQLLAGIYQGRWLSANSRN +LLIGAMEETTTGRRRMNAALPDAAALAHKTGTLTR-TASDIGIFRLADGRAVVAAIYVTG +QSASRAKRDARIADITRALYNGf +>[subseq from] class A beta-lactamase n=1 Tax=Luteibacter sp. 9135 TaxID=1500893 RepID=UPI000691093A +---LQASLQSLADKAPAHFGIIVTDLDDGTTA-RVGDDRAYMLMSVFKAPVAAAVLHGVD +AGTLHLDQRVHLTPADVVAGSPSIGTRAAKGVTVAELLSASVSQSDNTAVDALLKLLGGG +PKVTAYLDGKGVHGMRIDVGEREIGQAAIAMPQNTTTLDGAATFLRKLQAGELLSPVSTR +YLLSLMQAQVV-PTRIRAGLPAGFGIADKTGTGAYGAWNDMAIVTAPNGKSAVVAAFLRD +TTSTDDERAAWFRELGALVAA-- +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Alistipes communis TaxID=2585118 RepID=A0A4Y1WWV8_9BACT +---LERDLCRAVRGVDAEVGIAVVR--EGRVIaSVGGDRPMPAMSTFKFPLALAAAARLD +SLGLPLSAQLEVTGDDLWPWSPLREAHPAGGFSFGELLRYTVAESDNCACDRLIREIGGI +GALQRYVEGLPAEGLDFRMTEREMSGAPDAQRRNRATPEAMALLLDRFRHDSLFASEYRD +FLWQTLCTTTTGMNKLRAGLPDGTTIGHKTGSSDRDADNDLGYVELPDGSGYAICVYVAE +TALSDGETAALIAEISRLVWQ-- +>[subseq from] Beta-lactamase n=1 Tax=Pelosinus fermentans B4 TaxID=1149862 RepID=I9AWU6_9FIRM +-kELQKKIEATLAAYRGRWGMVILNHSSGQHF-TINPDMVFPAASMIKIPIMYEAMRQAA +AGRIDLEQLLIVKDELRVDGAGILKERPGISMTIRELVTLMIILSDNTATNMLIDLL-SM +SAINQTMERLGLKSTVLRRQMMDFAAA-AAGQENKTSSADIIRLLTIIYDHSHLPADYGK +LMIDILSRQQV-RDKLPFFLPEEIVIAHKTGTLP-GVEHDGGILFLPGG-PYIICIMTAD +LPAN-VEGLQLVAALGKVIYEHf +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium baderi TaxID=1332080 RepID=T0G5V3_9SPHN +----VSVIRDLGQSFNGHVGIAVRRVGAGWTV-AHNGNQLFPQQSVSKLWVSMAFLDAVD +RGKLRLTDTATITRQDLTLHQPSAAMVGATGTTYGNLMNRAMTQSDNTCNDALLRAVGGP +DAVRGFLARRFIGNIRFGPGERLLQSNYLANPPDGAAPASIVQALAKLKEGDMLSASSTA +TLLSIMGEAKTGPQRIKGGVPPGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTEPIPVRWQLMQAVAKAVAA-- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingobium wenxiniae (strain DSM 21828 / JZ-1) TaxID=595605 RepID=A0A562KN23_SPHWJ +----VSVIRDLGQSFNGHVGIAVRRVGAGWTV-AHNGNQLFPQQSVSKLWVSMAFLDAVD +RGKLRLTDTATITRQDLTLHQPSAAMVGATGTTYGNLMNRAMTQSDNTCNDALLRAVGGP +DAVRGFLARRFIGNIRFGPGERLLQSNYLANPPDGAAPASIVQALAKLKEGDMLSASSTA +TLLSIMGEAKTGPQRIKGGVPPGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTEPIPVRWQLMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter flavus TaxID=192812 RepID=A0A5P6NFH9_9SPHN +-rELDQAVSRIGGTFDGHVGIAVRDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD +AGRLDLSEMVAIRAADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA +EAVQDFLDTHGLASIRFGTDERSKQSSYLADPIDGAPPVALVEALARLQRGELLSAGSTG +LLLGTLARTKSGPQRLKAGAPEDWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR +TREPTPVRMEMMQQVVRAVAR-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9HR12_9BACT +-qKLEVAIKDVDRNLDGVLAVAILDLSTGQKY-LFHADEVLPTASSIKIAILAELYHQVQ +QGKLKLGDLYTLQSSDLVGGSGVAGALTPGVLTLRDVAALMISVSDNSATNVIIDRI-GM +ENVNALLDSLGLTHTRLRRKMMDVKAA-AEGRENIATPREMMILLEDLYRGKILNKQMTD +DFFELLSIHKE--SYIPRELPEDLRIANKPGELE-GVRNDSGIVFTGHR-PFVISVMTTY +LHRE-KDGGEAIIRIATAAYQMf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V582_9BACT +-------------------------------------------------MAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGPPASWVV---------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Alistipes communis TaxID=2585118 RepID=UPI001143AEB9 +---LERDLCRAVRGVDAEVGIAVVR--EGRVIaSVGGDRPMPAMSTFKFPLALAAAARLD +SLGLPLSAQLEVTGDDLWPWSPLREAHPAGGFSFGELLRYTVAESDNCACDRLIREIGGI +GALQRYVEGLPAEGLDFRMTEREMSGAPDAQRRNRATPEAMALLLDRFRHDSLFASEYRD +FLWQTLCTTTTGMNKLRAGLPDGTTIGHKTGSSDRDADNDLGYVELPDGSGYAICVYVAE +TALSDGETAALIAEISRLVWQ-- +>[subseq from] serine hydrolase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI0002898F93 +------------------------------------------------------------ +----------------------------------AKVMELMLVRSDNIAADQLLATLGGP +MAVQQWLWSHKITGIRVDRTIAQLLRGHLADSKDVATPVAMVALLYKLDNGTILSAQSRN +VLFDLMGRCQTGTRRIRALLPVGTRVEDKTGTLD-GVTNDVGVITMPDGRRVAIAIFARG +GR----DRQPVIAEVSRVIYDRf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Erythrobacter sp. RIFCSPHIGHO2_12_FULL_63_10 TaxID=1797975 RepID=A0A1F9ZDR3_9SPHN +--SFERRIAQLADGRQGRIGVAAIDLTTGRQI-AVLGDQLFPMASTSKIAVAATFLEMVE +QDKYSLTSEFALLLPVGSAFSSAAAPVRKGEMPAIDLIELMITRSSNPATDALLAAVGGP +AKVNDWVRRQGIKEFSINRDIATLVRAAHIDKRDAATPLAMVELLGGLYQGKFLSDESRR +VLLGAMSRTRTGKRRIPAQIPLEAQVSHKTGSLNN-TSSDVGIIQTPDGRAIALAVYVTG +H---------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Porphyromonadaceae bacterium TaxID=2049046 RepID=A0A3D6EAV0_9PORP +---IQLAIHSVINDKRATVGIAIL-CDDGNMV-VMNDDERYPVMSVFKFHVVVTALKKME +QHGIPLDSMTLIPQEQMLSYSPLREKYPNRDISYRNIIRYTMAHSDNNTCDFLIDFAGGI +SVVDSLIRQLGINKFAFSETEKTMHENILNCYNNWCTPSSMVLLLKKIYTEPILNNDHFL +FLEQVMIETSTGTNKIKAGLPADVILGHKTGSSDRTGDNDAGIIYLPHNKRCYIAIFIKD +SKENDTANAKIIADITEKIYE-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9SXA3_9BACT +--KLEASIADVDRNLDGVLGVAIEDLTTGQKY-LLHADDVFPQASSIKIAVLAELYHQAQ +QGKLKLTDFYVVQSSDLVPDSDIMGGLTPGVITLRDLATMTVAVSDNSATNVLIDRV-GM +ENVNALMDSLGLRHPRLRRKMMDLKAA-SEGRENVATPAEMMTLLEDLYRGKVLNKELTD +DFFRMLSTHKN--SFIPRDLPEGLKIANKPGELE-GVRNDSGIVFVDNR-PYIICVMTTY +LRR-ERDGEEAIRKISLETYRMf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2E6RWE6_9SPHN +-qELDREISRIGGTFAGHVGIAVHDIEAXRTL-HFNGLERFPQQSVSKLWVAMTALDEVD +AGRLDLAEMVEIRSRDLTVYQPIRKIVRRKGSDYADLIARAIXESDNTANDRVLRRVGGP +EAVQDFLDGHGLASIRFGTDERTKQSTYLADPPDGAPPVAIVEALARLYRGXLLSEXSTR +LLLDTLEQTKSGPRRLKAGAPEGWTVRHKTGTGQQSGYNDVGIVXSPXGRXXAXAVMIAR +TREPTPTRMEMMXXVVRAVVRY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium cupriresistens TaxID=1132417 RepID=A0A4Q4JL21_9SPHN +------VVRNLGQSFHGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD +RGKLRITDTTTITRNDLTLHQPSAALVAREGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRSFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKEGQMLSPASSR +LLLSIMAEAKTGPQRIKGGVPPGWHYLHKTGTGQSTGYNDIGIMSAPDGANYAVAVMIGS +TTVSIPERWALMQAVAKAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium czechense LL01 TaxID=1420583 RepID=A0A0J7XS53_9SPHN +------VVRNLGQSFHGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD +RGKLRITDTTTITRNDLTLHQPSAALVAREGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRSFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKEGQMLSPASSR +LLLSIMAEAKTGPQRIKGGVPPGWHYLHKTGTGQSTGYNDIGIMSAPDGANYAVAVMIGS +TTVSIPERWALMQAVAKAVVA-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Sphingobium TaxID=2611147 RepID=W1RXZ6_9SPHN +-----SVIRNLGQSFHGKVGIAVRRVGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD +RGKLRLTDTTTITRNDLTLHQPSAALVAKDGTSYSDLMRRAMTQSDNTCNDALLRAAGGP +DAVRGFLARRMIKDIRFGPGERLLQSNYLANPPDGAAPSSVVAALAKLKQGDMLSPASSR +LLLSIMEEAKTGPKRIKGGVPAGWSYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS +TTVSIPERWALMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. PAMC28499 TaxID=2565554 RepID=A0A4P7QMK1_9SPHN +---LVSVIQNLGQSFRGKVGIAVRRVGADWTV-AYNGNALFPQQSVSKLWVSMTFLDAVD +RGKIRLADSTTITKKDLTLHQPSAAMVGSGGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKEGDMLSSASAR +VLMNFMEEAKTGPQRIKGGVPHSWTYMHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTVSIPERWQLMQAVSRAVVA-- +>[subseq from] Beta-lactamase class A n=4 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A084EQW9_SPHYA +---LVSVIQNLGQSFRGKVGIAVRRVGADWTV-AYNGNALFPQQSVSKLWVSMTFLDAVD +RGKIRLADSTTITKKDLTLHQPSAAMVGSGGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKEGDMLSSASAR +VLMNFMEEAKTGPQRIKGGVPHSWTYMHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTVSIPERWQLMQAVSRAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A177J307_SPHYA +---LVSVIQNLGQSFRGKVGIAVRRVGADWTV-AYNGNALFPQQSVSKLWVSMTFLDAVD +RGKIRLADSTTITKKDLTLHQPSAAMVGSGGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKEGDMLSSASAR +VLMNFMEEAKTGPQRIKGGVPHSWTYMHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTVSIPERWQLMQAVSRAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacteraceae bacterium TaxID=2026738 RepID=A0A2D9PAZ4_9SPHN +-rELDREISRIGGTFPGHVGIAVRDIAARRTL-HFNGLQLFPQQSVSKLWVTLTALGEVD +AGQLELTEKVEIRDPDLTVHQPIRDIVRRRGTDYADLIERAITHSDNTANDRILRRVGGP +DVVQKFLDDHGLSSIRFGTDERTKQSAYLADPIDGAPPVAIVEALARLHEGKLLSGPSTA +LLLATMSRTKSGPQRLKAGAPQDWIVRHKTGTGQQSGYNDIGLFTSPDGRTYAIAVMIAR +TRVSIPERMAMMQEVVRAVVNY- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A3D0WLM1_9SPHN +-rELDREISRIGGTFPGHVGIAVRDIAARRTL-HFNGLQLFPQQSVSKLWVTLTALGEVD +AGQLELTEKVEIRDPDLTVHQPIRDIVRRRGTDYADLIERAITHSDNTANDRILRRVGGP +DVVQKFLDDHGLSSIRFGTDERTKQSAYLADPIDGAPPVAIVEALARLHEGKLLSGPSTA +LLLATMSRTKSGPQRLKAGAPQDWIVRHKTGTGQQSGYNDIGLFTSPDGRTYAIAVMIAR +TRVSIPERMAMMQEVVRAVVNY- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9P5K5_9BACT +-qKLEASIAEVDHNLDGVMGVAIEDLTSGQKY-QLRENEVFPQASSIKIAVLAELYRQAQ +QGKLKLTDLYVVKSVDLVEDSPIMNGLTPGVITLRDLATMVAAVSDNSAANILIDRV-GM +ENVNSFLDSLGLAHTRLRRKMMDLKAAG-EGRENISTPGEMMTLLDAIYRGKVLNKSLTD +DFFKVLSTKKN--SWIPRDLPENLKIADKDGELE-GVRNDSGVIFLENR-PYILCVMTTY +LRRE-RDGEEAISKISV------ +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf28 TaxID=1735695 RepID=A0A0Q4JKN4_9SPHN +--SLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD +QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGS +AAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TIRPMPERQKLIQNAAAAVAT-- +>[subseq from] class A beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI000578EE57 +---------------GARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +XGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTT------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A085K7G9_SPHYA +---LVSVIQNLGQSFRGKVGIAVRRVGADWTV-AYNGNALFPQQSVSKLWVSMTFLDAVD +RGKIRLADSTTITKKDLTLHQPSAAMVGSGGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKEGDMLSSASAR +VLMNFMQEAKTGPQRIKGGVPHSWTYMHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTVSIPERWQLMQAVSRAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Hormoscilla sp. GUM007 TaxID=2480854 RepID=A0A533NMJ2_9CYAN +--SLRQDVQTLASANELIPGVFILDLDRGAYM-EVNSSSTFAAASTIKLPILVAFFQDVD +AGLLRLDEQLTLRREHVATGSGSMQYHQGTQYSALEAARMMMTISDNTATNMLIEGLGGI +DVLNQRFESWGLRRTVVRNPLPDLEGT------NTTNPRDLAYLMARINQGSLTSGRSRD +RMLEIMGRTET-TPLLKPGLGEGATIAYKTGNIGS-MIADVGLISLPNGKRYIAAVMVNR +PFND-DRARELIAQISRAAYR-- +>[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=2 Tax=Sphingobacterium sp. JUb20 TaxID=2485110 RepID=A0A4R3AHA3_9SPHI +-qQLQERIKHIIDTTGGNIGVGVQGMDFKSGF-IINGNHEYPMMSVFKFPLAFAILDKVD +KGELKLSDKFHMPKASLDTWSPMVKDFPNQDVTLADLLTYSVSKSDNNACDFLYTKVGGP +VEVNQYLHYAGVKDISIVYTEGEMEKDWALQYKNWCKPAGAIRLLQLLYNQQLLSKTSND +FLIQIMRELPDWGKRITVLLPPTAELIHKTGASGMAAFNDIGIITLPNGQHLAIAVFVSD +FNAPQQRGINVIAAISKEIWDYy +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter gangjinensis TaxID=502682 RepID=A0A1J0VAC9_9SPHN +-eELEATLQDIGKDFGGSLGIAVVDVEQDWQA-GFNADTVLPQQSVSKTWVALTAMVMAE +AGELDLDAPIRVTREDLTLHQPIRKEILRDGTDHADLIERAIQQSDNTANNALLQRVGGP +EAIRAMLAEQGLEGIRFGPGEKPMQASYLADPVDGASAAAIAQAFAAIVRGDVLSEEGAD +TFLTIMANTRSGPRRLKGGREDGWVVSHKTGTGQQSGYNDVGVLFAPDSTPYAVAVMIGV +TERPTPERMEMMQSVTRAVIAY- +>[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI0014481CC4 +-------------NADLIPGVFLLDLDNGGYV-DINSNASFAAASTIKIPILIAFFQDVD +AGKIRLDEMLTLEKEMIAGGSGNMQYQPPDSYTALDVATKMMTISDNTATNMLIAKLGGQ +EVLNGRFRSWGLTTTMIRNPLPDLPGT------NTTSPRELGNLISMVNQGSVVSMRSRD +LILNIMSRTQR-DNLLPAGLGKGASAYHKTGDIGT-MLGDAGLVDVPTGKRYIAAIMVQR +PHND-PRAGKLISSISSAAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Granulicella tundricola (strain ATCC BAA-1859 / DSM 23138 / MP5ACTX9) TaxID=1198114 RepID=E8X484_GRATM +---LRQQIRATAEQAKGKVSVACSLPGTLLDC-DLHPDAHPPMQSVFKLPLGMAILDQVQ +RGRFTIDQPIRFLASDRIPYSPLQDEFPQADVPLRELLRLSVSLSDNCAADVLLRILGGP +KVLQAYIDSLGIEGFHIQDDEAGLHQDVLAQYRNWFEPSAAVALLRLINDRPPFSRQNTA +LLTGWMKTPPDRPSRVAQALPKGIEVLHKTGTSDY-ATNDIGLITLPDGRRLAVAVFVTD +ASADTATRDRVIAEISRQIYD-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Sphingomonas mucosissima TaxID=370959 RepID=A0A245ZFJ8_9SPHN +--ALLNAVQALGQSFNGDVGISVRDVEEGWTV-AWAGDKPRPQQSVSKLWVAIALMDAVD +RGRLGIDHSVTVRQSDLTLHQPIRPLVGKDGTTIGDLLHGAMTRSDNTANDVLLWRVGGP +DTVRRTLAEKGVAGVTFGPGERLLQARYLADPEDGASANGVTLGLALLAQGKLLSPASTE +KLLSLMRASKTGTLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLIVAPDGHRYAVAVMIAS +TRQPIPARMRLMGDVSRAIVS-- +>[subseq from] Uncharacterized protein n=1 Tax=Erythrobacter marinus TaxID=874156 RepID=A0A0H0XM52_9SPHN +---LATEIDRLALEFGGSTGIAVIDIKNGWST-GFEEEKILPQQSVSKLWVAITALEHAD +RGELSLSDKVRLTRDDLAVHQPIRARILNEVIDIAELIERALTESDNTANDAVLNAIGGP +DAVRAMLAKKEMIGIRFGPGERMMQSSYQSNPVDGATPLAIASALARLSRAEILSAGSRD +WLISVLRRTKSGPNRLKAGVPDGWEIAHKTGTGQQSGYNDVGLLLAPDGCNYAVAVMIGE +TRRETPDRMELMQGVARAVAEY- +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Alistipes communis TaxID=2585118 RepID=A0A4Y1XN26_9BACT +---LERDLCRAVRGVDAEVGIAVVR--EGRVIaSVGGDRPMPAMSTFKFPLALAAAARLD +SLGLPLSAQLEVTGDDLWPWSPLREAHPAGGFSFGELLHYTVAESDNCACDRLIREIGGI +GALQRYVEGLPAEGLDFRMTEREMSGAPDAQRRNRATPEAMALLLDRFRHDSLFASEYRD +FLWQTLCTTTTGMNKLRAGLPDGTTIGHKTGSSDRDADNDLGYVELPDGSGYAICVYVAE +TALSDGETAALIAEISRLVWQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. BK036 TaxID=2512122 RepID=A0A4Q7SK71_9SPHN +--SLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD +QGRIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGS +AAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TIRPMPERQKLIQNAAAAVANY- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. SD-21 TaxID=161528 RepID=A5PA76_9SPHN +-sALERTVAQLADGSRGRIGVYAIDLSTGQEI-GVLADQRFPMASTSKVAIAAVYLAGVD +AGKWTLSSEWRLPR-------------PGGALSAQQHLDLMISKSCNACTDALLDAVGGP +RAVNAWMRKAGIEEFQLDRTIASLVRASSVDLRDSATPRAMGQLLAGIYQGKWLSPSSRA +VIMNAMRATTTGKKRMRSALPVSAGLAHKTGTLSR-TASDIGIFHTPDGRAIAAAIYVTG +QSSSMAAEN-------------- +>[subseq from] Beta-lactamase n=1 Tax=Methylibium sp. T29-B TaxID=1437443 RepID=W7WML0_9BURK +------------------------------------------------------------ +-----------------------TEAYADGELTLAQLCHATITTSDNTAGNLILASYGGP +QALTQYARQLGDKITRLDRNEPDLNTRVEGGSLDTTSPRAMAMTMNKLLLGDALSPLSRN +LLRQWLLENTTGGKRLKAGTPADWTVGDKTGTNKT-DANDIGILLPPQGAPVLVTAYLAD +STASSQIKDATLAEVGRL----- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. AP50 TaxID=1884369 RepID=A0A1H6SQ95_9SPHN +-----NVVRNLGQSFRGKVGIAVRRIGSDWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD +RGKLRLADTTTITRNDLTLHQPTAALVAQNGSSYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGFLARRMIKDIRFGPGERLLQSNYLANPPDGAAPASIVQALAKLKQNEMLSSASSR +LLLSIMSEAKTGPQRIKGGMPPGWHYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTVSIPERWALMQGVAKAVAA-- +>[subseq from] serine hydrolase n=1 Tax=Pseudanabaena sp. UWO311 TaxID=2487337 RepID=UPI001157724E +-----SKIKDLAKEKDLSMQMMVVDLDSGAYV-QVGANQSIAAASTIKTPILVAFFQDVD +AGKIKLDEPIEMTADVKVGEAGDFQFLPTGTISALEVATQMIVISDNTATNMIIKRLGGT +SVLNQRFKSWGLNNVVVNNQLPDLEGT------NTISTQDMVSLLAMLDKGKLIEPRSRD +RFMDIMRRPVT-NTLLPKGIGENARIIHKTGDIGS-AVGDAGIVDMPNGKRYAIAVMVKR +PDND-QRANELIRQVSRATYDYf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. HMF7854 TaxID=2315330 RepID=A0A3R9Y4P2_9SPHN +------------------------------------------------------------ +--------------------------------SAARLMDAMLIHSNNVATDMLLRNLGGP +SAIQAWLNQHQVKGMRMDRTIAALLAARRWDVRDSTTPEAMVQFLRRLDSGDFISPSSRA +YLLGVMSRCETGKNRMKAFLPYGTKVEHKTGTLN-GLTGDVGFITMPDGRRVALAIFARN +GN----NRPRTIAATALAIYEGf +>[subseq from] serine hydrolase n=1 Tax=Phormidium sp. HE10JO TaxID=1765956 RepID=UPI000B400A99 +---LDSQLQELLGQYELTPGIMVVDVATGDYV-RIGEGSVFAAASTIKVPILVAFFQAVD +AGQVQLEERLRLEESHIQGGSGSLQYEAPGLLSALEVATLMIVESDNTATNLLIDRLGGF +AALNDRFRQWGMRETVLEDWLPDVQGT------NQTTPEELAGLLGQIERGELLSMGSRD +RLLRIMMMTEN-DTLLPQGLGTGAVIAHKTGNLR-GVLADAGLVDVPNGQRYVVVALVER +PEYD-DRAVELIRELSARVYGYf +>[subseq from] Uncharacterized protein n=1 Tax=Erythrobacter gangjinensis TaxID=502682 RepID=A0A0G9MQS7_9SPHN +-eELEATLQDIGKDFGGSLGIAVVDVEQDWQA-GFNADTVLPQQSVSKTWVALTAMVMAE +AGELDLDAPIRVTREDLTLHQPIRKEILRDGTDHADLIERAIQQSDNTANNALLQRVGGP +EAIRAMLAEQGLEGIRFGPGEKPMQASYLADPVDGASAAAIAQAFAAIVRGDVLSEEGAD +TFLTIMANTRSGPRRLKGGREDGWVVSHKTGTGQQSGYNDVGVLFAPDSTPYAVAVMIGV +TERPTPERMEMMQSVTRAVIAY- +>[subseq from] serine hydrolase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI000289E520 +---LTATITQLVRSFNGKVGVAVRSVDDGWMI-NAGGSQRLPQQSVSKLWVAMTVLAARD +AGKLRLDDPITLTRDDITLHQPIAGLIRGDTTTVGELLQRALTMSDNTANDRLLRLVGGP +TAVRGFIARKGLGAIGFGPGERMLQARYVAAPLDGAAPAAIATALARLKRGEILSAPSTS +YLIGTMQSSHTGKMRLRGAVPPGWTFGHKTGTGQTAGYNDVGLLIAPDGRTYAIAVMIGD +TLRPIPARQQLMQAVVSSVVA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Sphingobacterium sp. dk4302 TaxID=2662364 RepID=A0A5Q0Q6T5_9SPHI +-aQLKKDIETILSKYKAKVGIAIHNDDYTDSL-TVNAEHHYPFQSVYKFHLAIAVLNQVD +LGVLKLDQPITISKAAVTTYSPIKEQYPNGVLPLSKVIDFTVADSDNVGCDILFELLGGP +DKVQAYFIANGYQDLSIKLTEEVQQKDWEKQFQNWTTVGSSNKILYDYYRKHLLSETSHQ +FLWDTMRGTRTGLNRLKGDLPPGTVVAHKTGYSGTAAVNDIGVVSLPNDKVFFISVYVTD +SKEEEPVSAKIIAEVAAATWKY- +>[subseq from] D-alanyl-D-alanine carboxypeptidase n=1 Tax=Planctomycetes bacterium I41 TaxID=2528024 RepID=A0A517U3H2_9BACT +--ELAELIQPLIDAHQGDVAVAVKDLNTGETF-EHQAHKTMPTASLIKFPLMIAAYQAIE +EGTADPATLIELKESDKVPGSGILTTHFSDGISLRDAIQLMIVYSDNTATNLVANEV-GL +DKTAALMEKLGYPETKLHSFVFKRESRSVKFGLGSSTPADMASLLEKLQKKELVSQEASE +KMLGHLYACAD-KSTFPRNLP-NVKIAHKTGATNE-VRTDAGIVDGPKG-PIVLCVMTNE +NRDQENAGDVLCSKIAQAVYQHf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012450F69 +------------------------------------------------------------ +------KEKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Similar to Beta-lactamase class A n=1 Tax=Crocosphaera watsonii WH 8501 TaxID=165597 RepID=Q4C1V5_CROWT +---LQEKIQKIDAKYNVKPQAWFIDLDNGSYV-TYNGTQPVPAASTIKIPVLVAFFEEVD +KGNIHLDQMLTMTKDVMVSGSGDMQYGINKKFTALEVARKMIVISDNTATEMLVKQMGGK +EVLNKRFKEWGMKNTEINNILPELEGT------NKTSSEDLSKLLARIERGDLISARSRD +RLIDIMEGTRT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER +AYND-VAGRHLIQDISRTVYQHf +>[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. J1-007 TaxID=2661913 RepID=UPI0013281191 +---------RWAERWGGTLGAAVHDLGTGERA-EAAAGRSFTSASVIKVPLLAALLAGAE +AGDWSLDDRLPVGPRARVGGSGVLKDLADVPLSLRDLATLMIVLSDNTATNLLIDLV-GF +AAVNAWCARHGLRGTVLARRMLDADAR-ARGDENLTTAGDMAALFTGLVRGDLLGERSST +FALDVLARQQV-NDRLPRHLPDGARLAHKTGELP-GVRHDAGVVLPEGRAPIVVVVLTEG +VTDPRDRAADLIAETGRAVY--- +>[subseq from] class A beta-lactamase n=1 Tax=Alistipes communis TaxID=2585118 RepID=UPI0011450B34 +---LERDLCRAVRGVDAEVGIAVVR--EGRVIaSVGGDRPMPAMSTFKFPLALAAAARLD +SLGLPLSAQLEVTGDDLWPWSPLREAHPAGGFSFGELLHYTVAESDNCACDRLIREIGGI +GALQRYVEGLPAEGLDFRMTEREMSGAPDAQRRNRATPEAMALLLDRFRHDSLFASEYRD +FLWQTLCTTTTGMNKLRAGLPDGTTIGHKTGSSDRDADNDLGYVELPDGSGYAICVYVAE +TALSDGETAALIAEISRLVWQ-- +>[subseq from] Class A beta-lactamase (Fragment) n=1 Tax=Caulobacteraceae bacterium TaxID=1978230 RepID=A0A4Q3TYU4_9CAUL +---------------------------------------------------------RVQ +REEEQLDRAVAVTRADMIPHAPVTEKAIGRTLTIRELMQAAVEVSDNPAANILIREMGGI +AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPDQTIANIRELAFSDRLTPEHDQ +LISGWMIASPTGANRIKAGAPEGWTVAHKTGTGANGATNDIGMLTPLSGSPVLLAAYFTG +APATDDQRDAVIAEATRRALK-- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A3B9B022_9SPHN +-rELDREISRIGGTFPGHVGIAVRDIAARRTL-HFNGLQLFPQQSVSKLWVTLTALGEVD +AGQLELTEKVEIRDPDLTVHQPIRDIVRRRGTDYADLIERAITHSDNTANDRILRRVGGP +DVVQKFLDDHGLSSIRFGTDERTKQSAYLADPIDGAPPVAIVEALARLHEGKLLSGPSTA +LLLATMSRTKSGPQRLKAGAPQDWIVRHKTGTGQQSGYNDIGLFTSPDGRTYAIAVMIAR +TRVSIPERMAMMQDIVRAVVNY- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium mizutaii TaxID=1010 RepID=A0A239XUR4_9SPHI +---LKPQIDQVLANNKAKVGIAIHNDTFTDSL-IINGDYPYPMQSTYKFHLAIAVLDQVD +KGKLTLGQPVEISKETVSTYSPIKDKYPNGTLPLSEIIRYTVAESDNVGCDIMFGLLGGT +EQVQKYFEEKGYSEQSIKTTEEEQQANWDIQFQNWTKVSQANRILFDYYSKKLLSDSSHK +FLWDTMRSTSTGKDRLKGLLTQGTVVAHKTGYSGTGAVNDIGVIELPNGKVFYISVYVTD +SKETEPNSAKIIAEVSKAAYDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-CC-3G-468 TaxID=2135656 RepID=A0A4R1U4P4_9SPHN +----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAITVMDLRD +QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYGIAVMIGD +TIRPMPERQKLIQAAAAAVANY- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. UNC305MFCol5.2 TaxID=1449076 RepID=UPI00068954B7 +--ELVTSLDGITRNFNGLVGVAVTSIDDGWTAsNVTASRPLPQQSVSKLWVTMTVLDAVD +RGEIRLDDPLTITRADFTLHQPVAALVKGDVTTVAEIMRRAMQMSDNTCNDKLLRLVGGP +QAVRDFIARKQLGTIRFGPGEKLLQAAYVKDPPDGAAPASIADALARLYRGELLSANSTA +WLLATMDGAKTGKARVRGAVPPGWLYGHKTGTGQTAGFNDVGILTAPDGRSYAIAVMIGD +TSRPIRERQLLMQAVASAIVAH- +>[subseq from] Beta-lactamase n=1 Tax=Planctomycetales bacterium TaxID=2053591 RepID=A0A5K7XL11_9BACT +--DLADVVQPLIDAHRGDVAVKIKDLATGETF-EYHADKTMPTASLIKFPLMIASFQEFE +EGNVAPEAIVELDEKDKVPGSGVLTAHFSGGMPLRDAIRLMIVYSDNTATNLVAKKV-GL +DKTAKLMEKLGYPETKLHSYTFNRPSRSVKYGLGSTTPADMVSLLEKLWKKELVSKEASE +KMLTNLYACAD-KSTFPRYLP-DVKFAHKTGATEL-VRTDAGLMELPSGGPIAMCVMTNE +NKSPNNEGDVLCSKIAQAVYRYy +>[subseq from] Serine hydrolase n=2 Tax=Novosphingobium ginsenosidimutans TaxID=1176536 RepID=A0A5B8S5E3_9SPHN +--ALQAELSRIAASFEGQVGIAVTKAGCDWTV-GARLDQHFPQQSVSKLWVAMSVLDAVD +NGRMRLDQQITITPRDLTLNQPLQWEVLDKGRPVQMLMANALSLSDNTANDRLLWTVGGP +NHVRAFLKSREIAGIRFGPGERLLQSKYVADPMDGATPAGMAQALARLAKGELLSEQSTK +LLLDTMGKSRSGPMRLKAGLPPGWKAFHKTGTGQATGYNDVAVVEAPDGSYYGVAVLIGQ +THQPIRARMEMMQSVSAALA--- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Aminicenantes TaxID=910038 RepID=A0A1F5AFQ7_9BACT +------------------LGVALKDLKTGRTF-LLNEREVFPQASSIKIAVLYEMFKQAE +EGRLKLDEFIIVDEGRKVEGSGVLFYLGRPRLSVRDLAVLMVVLSDNTATNLLIDKV-GM +EAVNKRMDALGLSKTRLRRKMMDLKAA-AEGRENVSTPLEMMTLLEKIWKGGILGESYRK +DLLAILAIPKD--SPLRAGVPEGVEVAEKPGELE-AVRCDSGIVMLTGR-PYVLCVMTTY +LKRD-ADGNPAIAKISRIVYEH- +>[subseq from] Beta-lactamase n=1 Tax=Nodularia spumigena CCY9414 TaxID=313624 RepID=A0ZAJ6_NODSP +-----DAVQNLAIASNLRPGVFLVDLETGGYV-DVNSSATFSAASTIKVPILIAFFQDVD +AGKVRLDEMLRMEKEMVAGGSGNLQQQVGTQYSALELATQMSASSDNTATNMLIARLGGM +EALNQRFLRWGLSATAIRNPLPDLPGT------NTSSPRDLGNLLAMVNQGNLVSMRSRD +LILDIMRRTER-NHLLPSGLGAGARVYHKTGDIAT-MLGDVGLIDIPTGKRYIAAVMVQR +PNND-PLAEKLISAISGAAYQQf +>[subseq from] Serine hydrolase n=1 Tax=Pseudanabaena frigida TaxID=945775 RepID=A0A2W4Y874_9CYAN +-----SKIKELAKEKDLAMQMMVVDLDSGAYV-QIGANQPISAASTIKSPILVAFFQDVD +AGKIKLDEQLEMTADVKVGEAGELQLLPTGTISALETATQMIVVSDNTATNMIIKRLGGF +AALNQRFKSWGLNNIVVNSQLPDLEGT------NKISTQDMVSLLAMLDKGKLIEPRSRD +RFMDIMRRPVT-NTLLPKGIGEDARIIHKTGDIGS-AVGDAGIVDMPNGKRYAIAVMVKR +PDND-QRANELIRQISRVTYDYf +>[subseq from] Uncharacterized protein n=2 Tax=Bhargavaea cecembensis TaxID=394098 RepID=A0A163FIZ0_9BACL +--SLQGKIEKLLGETSARFGVSIRHLQSGEEV-RIRADERFQMASVFKVPILLSLYEQVH +EGRIDLTTRVALTKEERVPGSGILQELDPGLVTIKDLATLMTIVSDNMATDVLLGML-GK +EDVQETMKRIGAENISIVHSCWELLSMRTDLENNLCTPDDMTAILTKLAEGAFIDPAVSG +AVLDILYRQQL-NDRIPGRLPAGMPVAHKTGTIAS-AINDAGIIGLPGGGPLVVSIFSAD +NP-TTESGEAVIARIAETAYRHf +>[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A521PQP0_9CAUL +--ALQARLDELAAAYGEAVGIAVTDVEAGWTA-GVDQDRPYPQQSVSKLWVAIAVMKAAD +EGRLDPYGWVTLTDADRSVFQPVAYKIGSSGTPISDLLRRALVESDNAANDRLMRELGGP +DGVAATLQDMGLKDVKVGAYERDLQAAYLAAPLDGAAPAAITAALAALSRGELLSEASTG +RLIGLMEQARTGPRRLKGGLPAGWSIAHKTGTGQSVGINDVGLITAPDGHVYAVAVMMRH +TRQSVPARLAFMQSVTRAVAEQw +>[subseq from] serine hydrolase n=1 Tax=Sphingomonadaceae TaxID=41297 RepID=UPI00065C8420 +--DLLNAVEGLGQSFKGEVGISVRDLDEGWTV-AFNAERMLPQQSVSKLWVAIAVMDAVD +RGKLSLSDPVTVKKSDLTVHQPIRSLVTKAGTTVGKLLELAMTRSANSCNDVLLWKVGGP +QAIRAMLKRKGLDDVGFGPGERKLQARYLADPYDGASANGVTFGLMRLKQGKLLSARSTR +HLLGLMRASRTGPQRLRSGLRKGWTLAHKTGTGQATGYNDVGILVSPDGHRYAVAVMIAS +TRLPIPARMRLMGNVTRAIVR-- +>[subseq from] Uncharacterized protein n=1 Tax=Sphingobacterium cellulitidis TaxID=1768011 RepID=A0A235E0M0_9SPHI +htELKKQIDEILNSYDAKAGIAIHNHDFSDSL-SINGNHKYPLQSTYKFHLGIAILDQVD +KGKLSLDQPVVFSKEMMNTYSPIKDKFPNGVLPLSEVMRYTIAESDNLGCDAMFELLAGP +DKVQEYFVKKGYTEQSIKTNEAVQQADWDIQFQNWTKVSQANKILFDYYTKNLLSESSHK +FLWDTMRSTSTGKNRIKGLLPKGTTVAHKTGYSGTAAVNDIGVISLPNGQVLYISVYVTD +SKETEPQSASIVAKVSKAAFDYf +>[subseq from] serine hydrolase n=1 Tax=Cyanothece sp. BG0011 TaxID=2082950 RepID=UPI000D1EC3F9 +--ALKEKIQKIDAKYNVKPQAWFIDLDNGAYV-TYNGTQPIPAASTIKIPVLVAFFQEVD +KGNIHLDQMLTMTKDVMVSGSGDMQYMQENKFPAIEVARKMIVISDNTATEMLVKQIGGK +EVLNQRFKEWGMKNTEINNILPDLEGT------NKTSSEDLSKLLARIERGDLISARSRD +RLISIMEGTRT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER +AYD-DIAGRHLIQEISRTVYQHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. 67-41 TaxID=1895850 RepID=A0A1Q4E3T8_9SPHN +--ALDQAIRGITNNFEGLVGVAVTSIDDGWIV-ASNGERPMPQQSVSKLWVAMTVLDQVD +QGRIRLEDPITITRADFTLHQPVAALVKGDAASVGEIIRRAMQMSDNTCNDKLLRLVGGP +DAVRTFLARKGITGVRFGPGEKLLQASYVKDPPDGAAAAGISVALARLKRGELLSPTATA +WLLQTMDGAKTGRARVHGAVPPGWTYGHKTGTGQTAGFNDVGILTAPDGKSYALAIMIGD +THRPVRERQMLMQQVAQAIVT-- +>[subseq from] serine hydrolase n=1 Tax=Raoultella sp. 18102 TaxID=2681434 RepID=UPI00135CB146 +--ALKSSLERIASDAPGTLGIVVMDPASGTSV-KVNDGRPYLMMSAFKAPIAAAVLARVD +SGELKLDRTVHLVPADIVPGSPSLGKRLEAGVSVEELLRAAVTQSDNTAVDALLRLLGGG +AAATRFLESKGVHGMRIDFGERELSLQVLASHVNSTTLDGAAAFLEKLQAGALVSPSSTN +MLLGMMTAQVI-PNRVRAGLPAGFQLADKTGTAGLGAWNDMGIVTAPDGRRMIVAVFLSD +SPAAPKQADAWFAEIGRLVAA-- +>[subseq from] Uncharacterized protein n=1 Tax=Thermoprotei archaeon TaxID=2250277 RepID=A0A662UEV6_9CREN +-eRLESELVNLVKSFPAKVGVGFKDLKTGAEY-YINGRERFLTASVFKVFVLIELYNQVV +KGELDLRRRYRISEKVKVLGSGILKELDEGLPTLRDLAKLMMILSDNIATDIIMELL-GK +DRINRTVRELGLRETRVYLTTGEILLETDLEYNNVTTPEEMVRTLELLYRGEVLTPEACR +EILEIMKACQTGEARIKRYLPYNVKVAHKTGTMP-GVVNDAGIVFTEKGD-YVLVVFING +LNQYVPLGEELIAQISKKVYDVy +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A644UT93_9ZZZZ +--ELKKEIEIIVGGKDLKLGFALYDFSTGKSI-SINGNDKYPMQSVFKFPIGVALLDCVS +RGEFSLSDSVTLTKADLLPWSPIRERWPEGVLPLVSVMTYMVAHSDNNATDFLIHKIGGV +ARIQDIVNRLGAKKINIRNTEAEIQGSWSVQFDNWTTPNAMVDFLRLMNDGKLLDKANTA +VLWEIMASASS--GSVNRLVPKTVAFARKTGYSGANAQNDVGIIEFEDGRRVAYAIFLTD +STLGTDAGYDILAQIGKSIWKAy +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Sphingomonas dokdonensis TaxID=344880 RepID=A0A245ZDE9_9SPHN +--AMTASITQLVREFPGIAGVAVRAVDEGWTV-EAGGRRPLPQQSVSKLWVAMTVLDQRD +SGRLRLDDAVSLTPADLTLHQPSAVLVKNGVTTVSDLLFRALTQSDNTANDRLLTLVGGP +QAVRSFIERKQLGDIRFGPGERLLQARYIDNPPDGAAPLAIADALSRLARGELLSETSTR +LLISTMESSRTGRARLKAGISPGWTLAHKTGTGQNAGFNDVGLLTSPDGRRYAVAVMIGD +TERPMRERQQLIQAVAATVT--- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. YR768 TaxID=1884365 RepID=A0A1H9U6V5_9SPHN +-----NVVRNLGQSFRGKVGIAVRRIGSDWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD +RGKLRLADTTTITRNDLTLHQPTAALVAQNGSSYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGFLARRMIKDIRFGPGERLLQSNYLANPPDGAAPASIVQALAKLKQNEMLSSASSR +LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTVSIPERWALMQGVAKAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf230 TaxID=1735694 RepID=A0A0Q4J864_9SPHN +----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD +QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGHRYGIAVMIGD +TIRPMPERQKLIQAAAAAVANY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. PAMC26645 TaxID=2565555 RepID=A0A4P7R2U8_9SPHN +----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD +QGKIRLDEPILVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILIDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYGIAVMIGD +TIRPMPERQKLIQAAAAAVANY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium amiense TaxID=135719 RepID=A0A494VWD1_9SPHN +-----DVVRNLGQSFNGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD +RGKLRITDTATITRNDLTLHQPSAMMLKDGMTSYSDLLHRAMTQSDNTANDTLLRAVGGP +EAVRGYLARKTIRDIRFGPGERLLQSRYLANPPDGAAPSSIVQALARLKQNRMLSPASSR +LLMSIMSEAKTGPRRIKGGVPPGWTYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS +TTRPIPERMELMQAVSRAVAA-- +>[subseq from] serine hydrolase n=1 Tax=Calothrix sp. PCC 7103 TaxID=32057 RepID=UPI000376D121 +--SLKSAIQNLAIQNNLTPGVFVADLDNGGYV-DFNGGAMFSSASTIKLAILIAFFQEVD +EGKINLEETLRTSKSTVAGGSGDMQNRPGTEYGILEVATKMMTISDNTATNMLIERMGGI +EKLNQRFRSWGLNTTSLGNILPDIEGT------NKTSPKELSNLMAMITKGNIVSSQSRE +RIIDIMQRTVK-DTLLPPGLGQGAKIAHKTGEIG-GILADTGLVELPSGKRYLISVMVQR +PRND-VSAEKLINGISRAAYQQf +>[subseq from] serine hydrolase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=UPI0008477952 +---LVSVIQNLGQSFRGKVGIAVRRVGADWTV-AYNGNALFPQQSVSKLWVSMTFLDAVD +RGKIRLADSTTITKKDLTLHQPSAAMVGSSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKEGDMLSSASAR +VLMNFMEEAKTGPQRIKGGVPHSWTYMHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTVSIPERWQLMQAVSRAVVA-- +>[subseq from] serine hydrolase n=1 Tax=Rippkaea orientalis TaxID=2546366 RepID=UPI00017E6BD0 +---LKAKLDKIATQSKLKPQAWFMDLDNGAYV-SVNGSVPVPAASTIKIPVLVAFFEALD +AGKIHLDEILTMDKAIITSGAGNMQYPPGTKFTALETATQMIVISDNTATDMLIRRLGGK +EALNARFRDWGMTNTVINNRLPDLEGT------NTTTPEDLSKLLARIERGEVLTLRSRD +RLLGIMQETRT-RTLLPQGLEKDAIISHKTGDIGS-IIGDAGIIDIPNGKRYIGAVFTSR +PYND-PMGRALIQDFSRTTYQHf +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Candidatus Bathyarchaeota TaxID=1700837 RepID=A0A1F5DFS1_9ARCH +---LLEAVKKPAEGFKGVLGVSVNHLGTGESA-SLNGDRLFPTASVFKVPVIVEFYRQVE +RGVLSLDERVTLREVDKVPGSGILRELTEGLVSLRDLLSLMMIVSDNTATDLVAGRV-GF +DNVNRTLRGLGLTRTSISRYCREILFSLGTENNDVTTPNEMNRLIALVSEGKAASQESCD +QILGIMAKCQTGPARIPKYLPREVRLERKTGSLP-GIRNDVGIVTLRTGERYALSCFTMG +AE-DVYSAEEVIAQVSLNVYTHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127STE2_9BACT +--PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD +KQGLPLETELFISKPDLHPYGPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT +SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK +FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD +SMEDDKTNAAIIAQI-------- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter flavus TaxID=192812 RepID=UPI00141BD1D9 +-rALDQAVSRIGGTFDGHVGIAVRDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD +AGRLDLSEMVAIRTADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA +EAVQDFLDTHGLASIRFGTDERSKQSSYLADPIDGAPPVALVEALARLQRGELLSAGSTG +LLLGTLARTKSGPQRLKAGAPEDWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR +TREPTPVRMEMMQQVVRAVAR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas rubra TaxID=634430 RepID=A0A1I5R777_9SPHN +--QLQATVSQLLGNFGGKAGAAVRAVDEGWTV-EAGGRQRLPQQSVSKLWVAMTLLDLRD +QGRARLDEPITVLPADLTLHQPIAYLVAKSGTTVGGLLTRALTQSDNTANDRLLTYVGGP +EAVRRMILAKRLGDIRFGPGERALQARYTADPPDGAAPLAIADALARLARGELLSETSTR +ILLDTMGASVTGRARLRAALPVGWKISHKTGTGQNAGFNDVGLLTAPDGRRYALAVMIGD +TTRPIRERQQLIQAVAAAVAA-- +>[subseq from] Beta-lactamase (Fragment) n=5 Tax=Bacteria TaxID=2 RepID=C5IDC8_9BURK +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDE---------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium baderi TaxID=1332080 RepID=A0A0S3F3F1_9SPHN +---LVSVIRNLGQSFNGHVGIAVRRVGADWTV-AFNGNQLFPQQSVSKLWVSMAFLDAVD +RGKLRLSDTTTITRKDLTLHQPSAAMVGNTGTTYSNLMNRAMTQSDNTCNDALLRAVGGP +DAVRGFLARRFISNIRFGPGERLLQSNYLANPPDGAAPASVVQALAKLKQGDMLSPSSTS +ALLSIMGEAKTGPQRIKGGVPPGWHYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS +TTEPIPVRWQLMQAVAKAVAA-- +>[subseq from] PenP, beta-lactamase class A n=1 Tax=Nostoc flagelliforme CCNUN1 TaxID=2038116 RepID=A0A2K8T0D0_9NOSO +-----SQIRTLLASYTLNPGIFFLDLATGNYI-DINGEKRFAAASTIKFPLLVALFQEID +AGRIKLTDKLVMRRDLKVGESGTMQYKPGTKFSVLETATLMMTISDNTATNLILDRLGGA +AKVSQRFRSWGLQNTALRNLLPDIAGT------NTTSSKDLVRLAALVYNNRLLSPNSRN +QVLGIMRRVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR +PNHD-PKAGDFVRELSRRVYNY- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-CE-3G-477 TaxID=2135660 RepID=A0A2T5GYB0_9SPHN +----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD +QGKIRLDEPILVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP +SAVRSMIERKRLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYGIAVMIGD +TIRPMPERQKLIQAAAAAVANY- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium 13_2_20CM_57_17 TaxID=1803464 RepID=A0A1Q6YEY4_9BACT +-qKLEATINGVDRNLDGVLGVAILDLTTGQKY-FLHADEVLPTASSIKIAILAELYRQAQ +QGKIKLGVLYTLQSSDLVGGSGIAGALTPGVLTIRDVAALMISVSDNSATNIIIDRV-GM +ENVNMLLDSLGLTRTRLRRKMMDVKAA-AEGRENIATPREMVQLLEDLYRGKVLNKQMTE +DFFALLSVHKE--SYIPRELPEDLRIANKPGELE-GVRNDSGIVFTGNR-PFVISVMTTY +LRRE-KDGGDAIVRIATAAYQMf +>[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides sp. An322 TaxID=1965632 RepID=A0A1Y4ANI5_9BACE +-pALREQIQHIIGNAEAEIGVAVI-INGKDTL-TFNNEAHYPLMSVMKYHQALAVAHYLD +QRDLPLSTHIRIEKQDLRPYSPLRDKYPNGGLSIGELLTYTLQLSDNNACDILFEYIGGT +ASANQYLQTLGIEGFSISATENDMHQNPERCYENWSTPLSAARFMDSLIAGTLIDTAYTH +FIQETLLSCQTGKTRLPSPLQTDARIGHKTGTSDQNGINDVGFILLPDGKRYTVAVLVKH +SKLSYEETERIIADISTLIYQAy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T6T2_9BACT +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGD----------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. CAP-1 TaxID=2676077 RepID=UPI0012BB2A5C +------VVRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD +RGKLRITDSATITRSDLTLHQPSAALLKDGMTSYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRGFLARRMIRDIRFGPGERLLQSNYLASPPDGAAPASIVQALSKLKRNEMLSSASSQ +LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTVGIPERWALMQAVARAVAA-- +>[subseq from] class A beta-lactamase n=1 Tax=Luteibacter anthropi TaxID=564369 RepID=UPI00141EB454 +--NLRASLEQVANQAPGTMGILVMDPASHETI-KINDGRSYLMMSVFKAPVAATVLDQID +HGKLSFDQKVHLTPADVVGGSPSLGVRLKSGVTIDELLHAAVTQSDNTAVDALIRVLGGG +KTVTTYLESKGVRGMRIDMGERELGAAVLASKVNSTTLDGAGSFLDHLQAGQLLPPAFTK +RLLDMMTAQVI-PNRIRAGLPQGFQLADKTGTALIGAWNDIGVITGPDGRKKIVAVFLSD +SPADRKQADAWFAEVGRLVA--- +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Nostoc commune NIES-4072 TaxID=2005467 RepID=A0A2R5FQB2_NOSCO +-----SQIRTLLASYTLNPGIFFLDLATGNYI-DINGEKRFAAASTIKFPLLVALFQEID +AGRIKLTDKLVMRRDLKVGESGTMQYKPGTKFSVLETATLMMTISDNTATNLILDRLGGA +AKVSQRFRSWGLQNTALRNLLPDIAGT------NTTSSKDLVRLAALVYNNRLLSPNSRN +QVLGIMRHVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR +PNYD-PKAGDFVREVSRRVYNY- +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Sulfotelmatobacter kueseliae TaxID=2042962 RepID=A0A2U3K1Y3_9BACT +-qKLEASIQQVDQHLDGVMGVAIEDLTTGDHS-FLHEDEVFAQASSIKITVLAGLYLQAE +QGKLKLTDLYTVQSSDLVPDSYIMNGLTPGVVTLRDLATMMVAVSDNSATNVLIDRV-GM +PNVNAMLDSLGLTHTRLRRKMMDLEAA-KQGRENISTPREMMTLLDAIYHGKVMNKDSTA +DFFKVLSTNKD--SWIPRDLPADLKIANKPGALE-AVRNDSGVVFVEGR-PYVISVMTAF +LG-NERDGEEAISKISLEAWRMf +>[subseq from] Beta-lactamase class A n=1 Tax=Nodularia spumigena UHCC 0039 TaxID=1914872 RepID=A0A2S0Q3P4_NODSP +-----DAVQNLAIASNLRPGVFLVDLETGGYV-DVNSSATFSAASTIKVPILIAFFQDVD +AGKVRLDEMLRMEKEMVAGGSGNLQQQVGTQYSALELATQMSASSDNTATNMLIARLGGM +EALNQRFLRWGLSATAIRNPLPDLPGT------NTSSPRDLGNLLAMVNQGNLVSMRSRD +LILDIMRRTER-NHLLPSGLGAGARVYHKTGDIAT-MLGDVGLIDIPTGKRYIAAVMVQR +PNND-HLAEKLISAISGAAYQQf +>[subseq from] serine hydrolase n=1 Tax=Dolichospermum flosaquae TaxID=1166 RepID=UPI0014461044 +-----NSLQTLTANSDLIPGVFLLDLDNGGYI-DINSNISFAAASTIKIPILIAFFQDVD +GGKIRLDEMLTLQKEMIVGGSGNMQYQPTGSYTALDVATKMITISDNTATNMLVAKLGGQ +EALNGRFRSWGLITTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNMVSMRSRD +LILNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR +PNND-PRAAKLISSISSAAYQHf +>[subseq from] Beta-lactamase PSE-1 n=1 Tax=Dolichospermum sp. UHCC 0315A TaxID=1914871 RepID=A0A5C0DVE5_9CYAN +-----NSLQTLTANSDLIPGVFLLDLDNGGYI-DINSNISFAAASTIKIPILIAFFQDVD +GGKIRLDEMLTLQKEMIVGGSGNMQYQPTGSYTALDVATKMITISDNTATNMLVAKLGGQ +EALNGRFRSWGLITTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNMVSMRSRD +LILNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR +PNND-PRAAKLISSISSAAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Anabaena sp. 90 TaxID=46234 RepID=K7VYG2_9NOST +-----NSLQTLTANSDLIPGVFLLDLDNGGYI-DINSNISFAAASTIKIPILIAFFQDVD +GGKIRLDEMLTLQKEMIVGGSGNMQYQPTGSYTALDVATKMITISDNTATNMLVAKLGGQ +EALNGRFRSWGLITTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNMVSMRSRD +LILNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR +PNND-PRAAKLISSISSAAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. CAG:633 TaxID=1262744 RepID=R6FLJ6_9BACE +-tTLQSRISDFLKNKKATVGVSVL-TERGDTL-LYNNNLRYPLLSVFKFHIAMAVLDKMD +HAGTPLDSILHISSSQLQKYSPLRDKYPNQDISLRDLLKYSVSLSDNNACDILIDYAGGI +SKVDSYIRKLGIKNFHLSETENTMHQDPEKAYNNWSYPSEATRLLFIADTKTLFANNYKE +FLTEIMLGTTTGTDKLKGLLPPCTQVGHKTGSSDRNADNDLGFVTLPCGVKYYIAIFVMN +SYETDQENASIIAFISRLIYDE- +>[subseq from] Serine hydrolase n=1 Tax=Xanthomonadaceae bacterium TaxID=1926873 RepID=A0A4Q2XU83_9GAMM +--DLLNAVQALGTGFKGDVGISVRDIDEGWAV-AWEGDNPRPQQSVSKFWVAIAVMDAVD +RGRLSLNGAVTVTRSDLTLHQPIRALVGKHGTTIGELLRGAMTRSDNTCNDVLLWRVGGP +AAINRMLSEKGIAGVRFGPGERQLQARYLADPLDGASANGVTLGLSLLAQGKLLSARSTT +SLLTLMRSSKTGPLRLKSGLRTGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS +TRQPIPARMRLMGDVTRAIVA-- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc calcicola FACHB-389 TaxID=1357508 RepID=A0A1U7HP39_9NOSO +--ELKSPINKLVSRYKLTPGIFFMDLETGDYI-SVNGNKAFPAASTIKYPILIALFQEVD +AGRIKLNETLVMQRKYVVGGSGNMQYMRTGSFSVLKTATMMMTISDNTATNMIIARLGGI +AKLNQRFQSWGLQSTALRRMLGDFNGT------NKTSAKDLVRLSALMINNQLLSDKSQS +QVLGIMYGCHN-RKLLPSGLGSGAKIAHKTGTLRF-VLGDAGIIQTPSGKRYLAGIFVRR +PNND-LRARDFIRQVSQVVYGYf +>[subseq from] Beta-lactamase class A n=1 Tax=Dendrosporobacter quercicolus TaxID=146817 RepID=A0A1G9U2T0_9FIRM +---LRQHIETIIDQSSASWGIVIHRPATGQKL-EINPVQAFPAASMIKVPIMVEIMRQTA +AGIISLDDSLAVTSQVRVGGAGVLTERPDLTMTVRELVTLMIIISDNTATNLLIDLA-GM +PAINAAITNLGLNSTSLKRRMMDFAAA-QAGEENTTSAADMAALFELIRAKACLPPVYCD +LMLDLLSRQQV-RDKLPFYLPEEFKLAHKTGTLP-GVEHDGGILFFPAG-PCVVTVLAGN +LAAN-YQGLQWIAQIGKVIYDYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf208 TaxID=1735679 RepID=A0A0Q4EG27_9SPHN +----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD +QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYGIAVLIGD +TIRPMPERQKLIQAAAAAVANY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium fuliginis (strain ATCC 27551) TaxID=336203 RepID=A0A292ZIH9_SPHSA +--DLLNAVEGLGQSFKGEVGISVRDLDEGWTV-AFNAERMLPQQSVSKLWVAIAVMDAVD +RGKLSLSDPVTVKKSDLTVHQPIRSLVTKAGTTVGKLLELAMTRSANSCNDVLLWKVGGP +QAIRAMLKRKGLDDVGFGPGERKLQARYLADPYDGASANGVTFGLMRLKQGKLLSARSTR +HLLGLMRASRTGPQRLRSGLRKGWTLAHKTGTGQATGYNDVGILVSPDGHRYAVAVMIAS +TRLPIPARMRLMGNVTRAIVR-- +>[subseq from] Beta-lactamase n=1 Tax=Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) TaxID=269084 RepID=A0A0H3K538_SYNP6 +---LQTQLAALIQQQALKAELFLTDLDTGNYV-DINGTTSIPAASTIKIPVLAALMEAVQ +QGKVRLDEQLTMTQDLVASEAGAMQYPVGSKFTVLETAIEMIRISDNTATNLLIARLGGI +EAVNQRFAAWGLQTTRIRNLLPDLEGT------NSTTPKEMVELLAKVENGSLLDPRSRD +RFFAVLRTTET-NTLLSRGLGEEATIAHKTGDIAM-VVGDVGLIDMPSGKRYIAAMLVRR +PDND-LKANELIRQVSQRTYQ-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8YDY8_9BACT +-qKLAATVNEVDSKLDGVLAVAILDLTTGQKY-LLHADEVMPTASSIKIAILAELYRQAQ +QGGIKLTDFYTLQQSDLVGGSGITSVLTPGMLTLRDVAGLVISVSDNSATNVIIDRI-GM +ENVNALLDSLGLARTRLRRKMMDLKAA-SEGRENVATPREMMLLLENLYRGKVLNRQMTE +DFFNLLSVHKE--SYIPRNLPEDVKVANKPGELE-GVRNDSGIVFTGKR-PYVISVMTTY +LRRE-RDGGEAITRISDAAYQMf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf208 TaxID=1735679 RepID=UPI0012E17045 +--DLLNAVQALGASFKGEAGISVRDIDEGWVV-AWAGDSPRPQQSVSKFWVAIAVMDAVD +RGRLSLSDPVTVTRSDLTVHQPIRTLVGKDGTTIGELLRGAMTRSDNTCNDVLLWRVGGP +AAINRMLAEKEIAGVRFGPGERQLQARYLADPLDGASANGVTLGLSLLAQGKLLSARSTA +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS +TRQPIPVRMRLMGDVTRAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. IBVSS2 TaxID=1985172 RepID=A0A1Y2QPV4_9SPHN +--ALDQAIRGITNNFEGLVGVAVTSIDDGWIV-ASNGERPMPQQSVSKLWVAMTVLDQVD +QGRIRLEDPITITRADFTLHQPVAALVKGDAASVGEIIRRAMQMSDNTCNDKLLRLVGGP +DAVRTFLARKGITGVRFGPGEKLLQASYVKDPPDGAAAAGISVALARLKRGELLSPTATA +WLLQTMDGARTGRARVHGAVPPGWTYGHKTGTGQTAGFNDVGILTAPDGKSYALAIMIGD +THRPVRERQMLMQQVAQAIVT-- +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sp. Leaf257 TaxID=1736309 RepID=A0A0Q4UAK5_9SPHN +------------------------------------------------------------ +--------------------------------TAAKAMEAMIVRSDNLAADQMFATLGGP +AKVQQWVLSHNISGMRVDRTIAQLLRGHLADIKDVATPVAMVQLLRILDSGTALSSQSRA +YLLGLMRQCRTGTRRIRGLLPAGTLVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG +GR----DRQPVIAEVSRMIYDRf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2W6ST02_9SPHN +-----AVVRNLGQSFSGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD +RGKLRITDTTTITRNDLTLHQPSAMMLKDGMTSYSDLLRRAMTQSDNTANDALLRAVGGP +EAVRSYLARKAIRDVRFGPGERLLQSAYLANPPDGAAPSSIVQALARLKQNRMLSPASSR +LLMSIMSEAKTGPRRIKGGVPPGWTYLHKTGTGQSTGYNDIGIMTAPDGTSYAIAVMIGS +TTQPIPARMELMQAVSRAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudanabaena sp. UWO310 TaxID=2480795 RepID=A0A6C2E1Q5_9CYAN +--ALLAKIKELAKEKDLSMQMMMVDLDSGTYV-QIGANQPIAAASTIKTPILVAFFQDVD +AGKIKLDEPLEMTADVKVGQAGDLQYLPTGTISALETATKMIVISDNTATNMIIKRLGGA +VALNQRFKSWGLNSIVINNQLPDLEGT------NTISTQDLATLLSMLDRGKLIEPRSRD +RFMDIMRRPVT-NTLLPQGLGEDARIIHKTGDIAS-SVGDAGIVDMPNGKRYAIAVMVKR +PDND-QRANELIRQISRATYEYf +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter odishensis TaxID=1155476 RepID=UPI000E716842 +-eELSDKLEAIGEEFGGTLGIAVVDVDTGWST-GFNETALLPQQSVSKTWVTLTALTMAE +KGLLNLDAPIRVSREDLTLHQPIRKEILRSGTTVGELIERAIQQSDNTANNAILQRVGGP +RAVRAMLREQGLDGIRFGPGEKPMQANYLADPVDGARPIAIARALAAIERGEVLSPKRAE +EFLTIMSNTRSGPRRLKGGRAEGWVVSHKTGTGQQSGYNDVGVLFAPDSSAYAVAVMIGV +TKRPTIERMQMMQEVTRAVIA-- +>[subseq from] Beta-lactamase n=2 Tax=Parabacteroides goldsteinii TaxID=328812 RepID=A0A0J6CBE0_9BACT +-----DRIEKIIHGKKASVGVAILY--KDKMF-LISNGNKYPLMSVFKFHVAVAALKEME +YKGIALDSTVCIKAEQMHKYSPLRERYPDQDISYGSLIEYTASLSDNNTCDILIDFVGGI +SKVEAYIHTLGISDIQLTETEYTMHQNLDNCYRNWSTPQSVVALLKKVYTENVLSQEHFL +FLEQAMLSTPTGKNKLRAGLPECIALAHKTGQSGRTGDNDAGIVYLPSGEKCYIAVLIKD +SKETDAENASIIADIAKEVYN-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf20 TaxID=1735685 RepID=A0A0Q4G0G7_9SPHN +--DLLNAVQALGASFKGDAGISVRDIDEGWVV-AWEGDSPRPQQSVSKFWVAIAVMDAVD +RGRMSLSDPVTVTKSDLTVHQPIRTLVGADGTTIGELLRGAMTRSDNTCNDVLLWRVGGP +DAINRMLAEKGVAGVRFGPGERQLQARYLAAPLDGASANGVTLGLSLLAQGKLLSARSTA +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAIAVMIAS +TRQPIPVRMRLMGDVTRAVVA-- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A349PDT0_9BACT +-------IEKTSGAYRGRVGIYLKDIQTGRVW-EYNAAGLFPSASLIKVPIMAAVFEKIK +LGAITLDTQIRLTNRGRVGGSGSLKWVREGTLSVMEIIYKMITESDNTATKMLIDYV-GM +PYLENSFRKLGLVQTNITPEGMSLASG-RVKNENYTTAREMAGLMERIYEGELVNREASE +FMLDVLKHTKS-RSRLRRGLPLGWEIGHKTGLLRR-SCHDVGIVFSPRGD-FVLAVLTSE +VP-DYTSAKNFITRVAKLTYAYy +>[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. CAG:755 TaxID=1262935 RepID=R5GFE1_9BACT +--SLRNEMSRVTAGLHATVGVSFIH--NGRLF-TFNDSVHYPMMSVYKVPVALAVLQKMS +STGTSPATRIEVKREQWHPYSPMREAFRDSSIRLADLLHYCVAMSDNNAADILTAYVGGI +TVVARTVESLIGKKMHISETEQDMHENTENVYNNWCHPSAMAILLQEIYEGNALDSSARA +YFERLMRSTQTGTDKMPAGLPPGIALGHKTGSSDKAGDNDAGVIYMPDGKRCYAAVFIKD +STESDATNAQTIATLTRLIYR-- +>[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium UBA11372 TaxID=2055768 RepID=A0A350XJ15_9CYAN +-----AEITALEQYPKLTPGIFILDPDTDGYF-DLNGTSAIASASTIKIPILVAFFQDVD +AGKIRPDELLTMKPQFIATGSGNMQKFPGSKYTALETATKMITISDNTATNMLIERLGGA +EALNQRFASWGLTATAIRNQLPDVEGT------NTTSAKDLANLIAFVNQGELVSRQSRL +SLLSIMRRTER-NHLLPRGLGQGATIAHKTGYIG-AMLADAGLIELPNGKRYIAAVMVKR +PQND-PRAEKLIRQISRIAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera malacea cyanobiont' DB3992 TaxID=1206980 RepID=A0A2D0HFP3_9NOSO +----TSQIRTLLASYSLNPGIFFLDLDTGNYI-DINGEKRFAAASTIKFPLLVALFQEID +AGRIKLSDKLVMRRDLKVGESGIMQYKPGTKFSVLETATLMMTISDNTATNLVLDRLGGA +AKVSQRFRSWGLQNTAMQNLLPDIGGT------NTTSSKDLVRLAALVSNNRLLSPASRN +QVLGIMRRVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR +PNYD-RRAGDFVREVSRRVYNY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Myroides sp. N17-2 TaxID=2030799 RepID=UPI000EFB1A8A +-qKLKQQIEPILQHKKATVGIAIIY-DGKDTL-TFNNDHKYPTMSVYKFFQALTILDYMD +KHNIDLNTPMFIKKEDLKEYSPLRDKRPMGDMPIGELIQYTASHSDNNISNLFFSSLIGP +KMTDLYYRSIGIKEFEIVSSEEEMSLDFNNQYDNWITPLEATRILELFHRKELLSPKYKA +FLQQAMIDTKSGQDKVKALLPKNTVVVHKTGMSFRAVDNDLALVYLPNGKQFSIAVFVMD +SLEDDKTNASIIAQVAKVAYDYy +>[subseq from] Beta-lactamase n=1 Tax=Nostoc sp. 'Lobaria pulmonaria (5183) cyanobiont' TaxID=1618022 RepID=A0A2L2NK45_9NOSO +----TSQIRSLLASYTLNPGIFFLDLDTGNYI-DINGEKRFAAASTIKFPLLVALFQEID +AGRIKLTDKLVMRRDLKVGESGIMQYKPGTKFSVLETATLMMTISDNTATNLVLDRLGGA +AKVSQRFRSWGLQNTALRNLLPDIAGT------NTTSSKDLVRLAALVSNNRLLSPTSRN +QVLGIMRHVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR +PNYD-PKAGDFVREVSRRVYNY- +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Serratia TaxID=613 RepID=U6A4G9_SERFO +--------------------------------------------------AVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPVAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPQAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTTWVVGD-------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Leptolyngbya sp. TaxID=47254 RepID=A0A2W7AQA1_9CYAN +---LQQRLASLRSGASLKPGMFFMDLETGNYA-EVNGDKVYPTASIIKLPILIALFQEVD +AGNIRLNETLTMTRDVIVGGSGEIQDLPPGTFSLLETATKMIVISDNTATNMIIKRMGGI +QVLNARFRSWGLQKTAMRNMLPDLKGT------NTTTARELVRLLAMLDKQQLLSSQSQG +QVLNILQRVRN-RTLLPVGLARGATIAHKTGDIGF-ILGDAGIIQMPTGKRYLAAVLVES +AY-DDPSARDFIQDVSRIVYTY- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. ATCC 43529 TaxID=1840705 RepID=A0A367PW02_9NOSO +----SSQIRTLLASYTLNPGIFFLDLDTGNYI-DINGEKRFAAASTIKFPLLVALFQDID +AGKIKLTDKLVMRRDLRVGEAGTMQKPIGTKFSVLETATLMMTISDNTATNMVLDRLGGA +AKVSQRFRSWGLQNTAMQNLLPDIPGK------NTTSSKDLVRLAALVYNNRLLSPNSRD +RVLGIMRGVKT-NSLLPAGIGKGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR +PNHD-PKAGDFVREVSRRVYNY- +>[subseq from] UPI0014399A39 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0014399A39 +---LQSRVDALVRSFPGKAGAAIVAVDEGWSV-ERGGSLSLPQQSVSKLWVAMTVLAQRD +AGRLKLDDPVLVTRDDLTLHQPIAGLVRGEGTTVGALMTRALTQSDNTANDRLLTFVGGP +SAVRAFISEKRLGAIRFGPGERLLQSRYVDNPPDGAAPLAIADALARLARGELLSETSTR +LLLETMTASRTGHARLRAATPAGWELAHKTGTGQNAGFNDVGLVTAPDGRRYAVAVMIGD +TTAPIRDRQRLIQNVASSL---- +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter oceanensis TaxID=1463597 RepID=UPI001369BBB0 +--SLERRVAMVADGDRGRIGVYAIDLTTGREV-GILADQRFPMASTSKVAIAAAYLAGVD +KGRWTLSSEWRLPRA------------GGTYMPAHQHLKLMIAKSCNDCTDALLEAVGGP +AAVNRWMKEAGIEDFQLNRYISSLVRASSIDLKDSATPRAMGQLLAGIYQGKWLSASSRR +VLLDAMEQTTTGKKRMPAALPMSANLAHKTGTLSR-TASDIGIFYTPDGRAIAAAIYVTG +QSPSMAAEN-------------- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc calcicola FACHB-389 TaxID=1357508 RepID=A0A1U7HXG5_9NOSO +-----SQIRTLLASYTLNPGIFFLDLDTGNYI-DINGEKRFAAASTIKFPLLVALFQEID +AGRIKLTDKLVMRRDLRVGESGTMQKPVGTKFSVLETATLMMTISDNTATNMVLDRLGGA +AKVSQRFRSWGLQNTALRNLLPDVAGT------NTTSSKDLVRLAALVSNNRLLSPNSRN +QVLGIMRRVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR +PNYD-PKAGDFVREVSRRVYNY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf30 TaxID=1736213 RepID=A0A0Q4K649_9SPHN +-----TAIDALHHDFAGKAGIAIRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD +QGKAKLEDPVVVRAEDLTLHQPIAMLVTGDGTTVGELLRRALTHSDNTANDRLLSYVGGP +RAVRGMILRKQLGEIRFGPGERLLQSAYVANPPDGAAPIAIADALARLARGELLSASSTQ +VLLDTMGASVTGRARLRAALPAGWRIAHKTGTGQNAGFNDVGLLTAPDGKRYAIAVMIGD +TLRPIRERQMLIQAVAAAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. KY5 TaxID=2011159 RepID=A0A2Z4K1L3_9SPHN +--AFEQKLEEIGASLSGTVGIAVEDVDTGELY-EFNGDEMLPQQSVTKLWVAMAALSQVD +QGDLKLTERVRIGRDDLTLHQPIREIVKARGTNYRDLFERSITRSDNTANDRLLRRVGGP +EVVQKWLSDNQLDGIRFGTDERSKQSGYLADPIDGASANAIASALAKLARGDLLGENTTM +LLRNTLEQTRSGPRRLKGGAPDGWRVEHKTGTGQQSGYNDVGILTSPDGREYAVAVLIGR +TSEPTPVRMDMMQQVTIAIAE-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas aerolata TaxID=185951 RepID=UPI000D3D1A48 +-----TAIDALHHDFAGKAGIAIRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD +QGKAKLEDPVVVRAEDLTLHQPIAMLVTGDGTTVGELLRRALTHSDNTANDRLLSYVGGP +RAVRGMILRKQLGEIRFGPGERLLQSAYVANPPDGAAPIAIADALARLARGELLSASSTQ +VLLDTMGASVTGRARLRAALPAGWRIAHKTGTGQNAGFNDVGLLTAPDGKRYAIAVMIGD +TLRPIRERQMLIQAVAAAVAA-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. STIS6.2 TaxID=1379700 RepID=UPI000D13F7E5 +-----TAIDALHHDFAGKAGIAIRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD +QGKAKLEDPVVVRAEDLTLHQPIAMLVTGDGTTVGELLRRALTHSDNTANDRLLSYVGGP +RAVRGMILRKQLGEIRFGPGERLLQSAYVANPPDGAAPIAIADALARLARGELLSASSTQ +VLLDTMGASVTGRARLRAALPAGWRIAHKTGTGQNAGFNDVGLLTAPDGKRYAIAVMIGD +TLRPIRERQMLIQAVAAAVAA-- +>[subseq from] Serine hydrolase n=3 Tax=unclassified Sphingomonas TaxID=196159 RepID=A0A0Q4I602_9SPHN +-----TAIDALHHDFAGKAGIAIRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD +QGKAKLEDPVVVRAEDLTLHQPIAMLVTGDGTTVGELLRRALTHSDNTANDRLLSYVGGP +RAVRGMILRKQLGEIRFGPGERLLQSAYVANPPDGAAPIAIADALARLARGELLSASSTQ +VLLDTMGASVTGRARLRAALPAGWRIAHKTGTGQNAGFNDVGLLTAPDGKRYAIAVMIGD +TLRPIRERQMLIQAVAAAVAA-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. T1 TaxID=2653172 RepID=UPI001358A6EE +-----TAIDALHHDFAGKAGIAIRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD +QGKAKLEDPVVVRAEDLTLHQPIAMLVTGDGTTVGELLRRALTHSDNTANDRLLSYVGGP +RAVRGMILRKQLGEIRFGPGERLLQSAYVANPPDGAAPIAIADALARLARGELLSASSTQ +VLLDTMGASVTGRARLRAALPAGWRIAHKTGTGQNAGFNDVGLLTAPDGKRYAIAVMIGD +TLRPIRERQMLIQAVAAAVAA-- +>[subseq from] serine hydrolase n=1 Tax=unicellular cyanobacterium SU3 TaxID=1982589 RepID=UPI000B3E1A08 +--ALKEKIQKIDAKYNVKPQAWFIDLDNGAYV-TYNGTQAVPAASTIKIPVLVAFFQEVD +AGNMHLDQMLTMTKDVMVSGSGDMQYMQENKFPAIEVARKMIVISDNTATEMLVKQIGGK +EVLNQRFKEWGMKHTEINNILPDLEGT------NKTSSEDLSKLLARIERGDLISARSRD +RLIAIMEGTKT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER +AYD-DIAGRHLIQDISRTVYQHf +>[subseq from] Serine hydrolase n=1 Tax=Nodularia spumigena CENA596 TaxID=1819295 RepID=A0A166I2Q2_NODSP +-----DAVQNLAIASNLRPGVFLVDLETGGYV-DVNSSATFSAASTIKVPILIAFFQDVD +AGKVRLDEMLRMEKEMVAGGSGNLQQQVGTQYSALELATQMSASSDNTATNMLIARLGGM +EALNQRFLRWGLSATAIRNPLPDLPGT------NTSSPRDLGSLLAMVNQGNLVSMRSRD +LILDIMRRTER-NHLLPSGLGAGARVYHKTGDIAT-MLGDVGLIDIPTGKRYIAAVMVQR +PNND-PLSEKLISAISGAAYQQf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Serratia fonticola TaxID=47917 RepID=U6A4I8_SERFO +--------------------------------------------------AVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPQAMAKSLQNLTLGKALAEPQRA +QLVEWMKGNTTGGASIRAGLPTTWVVGD-------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured Bacteroides sp. TaxID=162156 RepID=A0A1C5V3Z5_9BACE +--SLRNEIIHSICKYDAKVGVAVM-VNNTDTL-TVNNSDKYPMMSVFKFHQALAVCHFLQ +MKGIPLDSVINISKEELREYSPLRDRFPEGNISLLELMEYTLQLSDNNACDILFNRILSI +KETDRYIRSLGIDDFSIEMDENDMHENLDNCYSNWTTPMAAVRLINLFLEGDAVSGEYYD +FIKRTMTECTTGTGRLPYPLKTAAVIGHKTGTGDKNGINDIGFIDLPNGDRYLIAVFVKD +SAENYETTEKIIAEISSIVYK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas aerolata TaxID=185951 RepID=A0A2T4YVX7_9SPHN +-----TAIDALHHDFAGKAGIAIRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD +QGKAKLEDPVVVRAEDLTLHQPIAMLVTGDGTTVGELLRRALTHSDNTANDRLLSYVGGP +RAVRGMILRKQLGEIRFGPGERLLQSAYVANPPDGAAPIAIADALARLARGELLSASSTQ +VLLDTMGASVTGRARLRAALPAGWRIAHKTGTGQNAGFNDVGLLTAPDGKRYAIAVMIGD +TLRPIRERQMLIQAVAAAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus elongatus PCC 11801 TaxID=2219813 RepID=A0A3G6X3A5_SYNEL +---LQTQLAALIQQQTLKAELFLTDLDTGNYV-DINGTTSIPAASTIKIPVLTALMEAVQ +EGKVQLDEQLTMTKELVASEAGAMQYPVGSKFTVLESAIEMIRISDNTATNLLIARLGGI +EAVNQRFAAWGLETTRLRNLLPDLEGT------NSTTPKEMVELLAKIENGSLLKPRSRD +RFFAVLRTTET-NTLLSRGLGEEATIAHKTGDIAM-VVGDVGLIDMPNGKRYIAAMLVRR +PDND-LKANELIRQVSQRTYQ-- +>[subseq from] Beta-lactamase n=1 Tax=Nostoc linckia z16 TaxID=1628751 RepID=A0A2C6W0A7_NOSLI +--ELKTPINKLVSRYKLTPGIFFMDLETGDYI-SVNGNKAFAAASTIKYPILIALFQEVD +AGRINLNETLVMQRKYVVGGSGSMQKRVGSKFSVLKTATMMMTISDNTATNMIIARLGGI +PKLNQRFRSWGLQSTALHRMLGDFNGT------NKTSAKDLVKLSALMVSNQLLSDKSKS +QVLGIMYGCHN-RKLLPSGLGSGAKIAHKTGTLRF-VLGDAGIIQTPSGKRYLAGIFVKR +PNND-LRARDFIRQVSQVVYGYf +>[subseq from] Beta-lactamase n=1 Tax=Crocosphaera watsonii WH 8502 TaxID=423474 RepID=T2I6S8_CROWT +---LQEKIQKIDAKYNVKPQAWFIDLDNGSYV-TYNGTQPVPAASTIKIPVLVAFFEEVD +KGNIHLDQMLTMTKDIMVSGSGDMQYGINKKFTALEVARKMIVISDNTATEMLVKQMGGK +EVLNKRFKKWGMKNTEINNILPDLEGT------NKTSSEDLSKLLARIERGDLISARSRD +RLIDIMEGTRT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER +AYND-VAGRHLIQDISRTVYQHf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9N8D3_9BACT +-qKLQVSIAGTDRELDGILGVSIQDLSSGEQF-SLHGDEVFPQASSIKIAVLAELYRQAA +QGKLKLTDLYTVNSADLVADSYIMNGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GI +ENVNALLDSLNLPHTRLRRKMMDIKAA-AEGRENISTPNEMAGLLRAVYQKKFFDAALTE +DLFKVLSTPK--DSWIPRELPDDLKIANKPGSLE-GVRNDSGIIFLANR-PYILCVMTTY +LRR-ERDGEQAISRISLAAWRMf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. T1 TaxID=2653172 RepID=A0A654B731_9SPHN +-----TAIDALHHDFAGKAGIAIRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD +QGKAKLEDPVVVRAEDLTLHQPIAMLVTGDGTTVGELLRRALTHSDNTANDRLLSYVGGP +RAVRGMILRKQLGEIRFGPGERLLQSAYVANPPDGAAPIAIADALARLARGELLSASSTQ +VLLDTMGASVTGRARLRAALPAGWRIAHKTGTGQNAGFNDVGLLTAPDGKRYAIAVMIGD +TLRPIRERQMLIQAVAAAVAA-- +>[subseq from] Beta-lactamase n=1 Tax=Calothrix sp. PCC 6303 TaxID=1170562 RepID=K9V5T9_9CYAN +---LKSAITNLTTTTNFTTGVFLVDLDTNSFV-DINGARTFSSASTIKLPILIALFQEVD +AGKIRLEDSIATKQELLAGGSGDIQQPIGTKYTILDLATKMITISDNTATNMLIERLGGI +ENLNQRFRGWGLASTSLRNLLPDLKGT------NTTSPKDLAGLIAMITKGNIVTNQSRD +RILDIMRRTVK-DTLLPSGIDQGATIAHKTGDIAS-MVADVGLIESATGKRYIAGVMVER +PNND-NRAETLISSISRLTFQ-- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Acidobacteria (miscellaneous) TaxID=305072 RepID=A0A2V8XDJ7_9BACT +-qKLATTVNEVDRNLDGVLAVAILDLSTEQKY-LLHADEVMPTASSIKIAILAELYRQAQ +QGKLKLTDFYTLQSSDLVGGSGISSVLTPGALTLRDVAGLMISVSDNSATNVIIDRV-GM +ENVNALLDSLGLTHTRLRRKMMDLKAAG-EGRENIATPREMMLLLESLYRGKVLNKQMTE +DFFNLLSVHKE--SYIPRELPEDLKVANKPGELE-GVRNDSGIVFTGKR-PYVISVMTTY +LRRE-RDGGEAIIKISNAAYQMf +>[subseq from] Beta-lactamase enzyme family protein n=2 Tax=Lyngbya aestuarii TaxID=118322 RepID=U7QP35_9CYAN +---VKQQILALTENSDLKPGVLLVDLDTGGYV-DINSESAFAAASTIKVPILVAFFQAVD +EGKISLNEVLTMEDQHIAGGSGDMQYQSAGTYTALETATKMIVISDNTATNMLIERLGGA +EFINQKFLDWGLHNTVIRDVLPDLRGT------NKTTPKDLVNLLTQLNQGGLVSMKSRD +RIFRIMEKTEN-DSLLASGLGRGAIIAHKTGNLKS-VSGDVGLIDLPNGKRYLLAVLVER +ND-DDSAAESLIRNISKTVYESf +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides ndongoniae TaxID=1903262 RepID=UPI000DE5A566 +-tTLQSRISDFLKNKKATVGVSVL-TERGDTL-LYNNNLRYPLLSVFKFHIALAVLDKMD +HAGTPLDSILHISSSQLQKYSPLRDKYPNQDISLRDLLKYSVSLSDNNACDILIDYAGGI +SKVDSYIRKLGIKNFHLSETENTMHQDPEKAYNNWSYPSEATRLLFIADTKTLFANNYKE +FLTEIMLGTTTGTDKLKGLLPPCTQVGHKTGSSDRNADNDLGFVTLPCGVKYYIAIFVMN +SYETDQENASIIAFISRLIYDE- +>[subseq from] serine hydrolase n=1 Tax=Candidatus Sulfotelmatobacter kueseliae TaxID=2042962 RepID=UPI000D109E6D +-qKLEASIQQVDQHLDGVMGVAIEDLTTGDHS-FLHEDEVFAQASSIKITVLAGLYLQAE +QGKLKLTDLYTVQSSDLVPDSYIMNGLTPGVVTLRDLATMMVAVSDNSATNVLIDRV-GM +PNVNAMLDSLGLTHTRLRRKMMDLEAA-KQGRENISTPREMMTLLDAIYHGKVMNKDSTA +DFFKVLSTNKD--SWIPRDLPADLKIANKPGALE-AVRNDSGVVFVEGR-PYVISVMTAF +LG-NERDGEEAISKISLEAWRMf +>[subseq from] serine hydrolase n=1 Tax=Synechococcus elongatus TaxID=32046 RepID=UPI000F7F5C3B +---LQTQLAALIQQQALKAELFLTDLDTGNYV-DINGTTSIPAASTIKIPVLAALMEAVQ +QGKVRLDEQLTMTQELVASEAGAMQYPVGSKFTVLETAIEMIRISDNTATNLLIARLGGI +EAVNQRFAAWGLQTTRIRNLLPDLEGT------NSTTPKEMVELLAKVENGSLLDPRSRD +RFFAVLRTTET-NTLLSRGLGEEATIAHKTGDIAM-VVGDVGLIDMPSGKRYIAAMLVRR +PDND-LKANELIRQVSQRTYQ-- +>[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI0014479C54 +-----NSLQTLTANSDLIPGVFLLDLDNGGYI-DINSNISFAAASTIKIPILIAFFQDVD +EGKIRLDEMLILQKEMIVGGSGNMQYQPTGSYTALDVATKMITISDNTATNMLVAKLGGQ +EALNGRFRSWGLITTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNMVSMRSRD +LILNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR +PNND-PRAAKLISSISSAAYQHf +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Nostoc linckia NIES-25 TaxID=1091006 RepID=A0A1Z4LE45_NOSLI +---LSSQIRSLLASYSLNPGIFFLDLATGNYI-DINGEKRFAAASTIKFPLLVALFQDID +AGKIKLTDKLVMRRDLKVGESGTMQYKPGTKFSVLETATLMMTISDNTATNLVLDRLGGA +AKVSQRFRSWGLQNTAVRNLLPDVAGT------NTTSSKDLVRLAALVSNNRLLSPNSRD +RVLDIMRHVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR +PNYD-PKAGDFVREVSRRVYNY- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3C0XQN4_9CHLR +--TVASEIERLADATGGIVGLAATQLATGRHI-GHREDELFPTASVIKLPLLVTLYEDAI +AGRIDLSERVVYREGTKVAGSGVLQYLDDGLPTLRDLSVLMMSVSDNTATDLLFDRV-GK +TRIEATMDRLGLSSTRVPFDIRAMLMSMIPDQADRTTPADMSRLLELIESRSILDADACT +AIIELMKRSQS-GTRIPGLLPKGTVVAHKTGSYRR-LRNDVGIVYAPNG-PYVIALFARE +LARDNVDDDGALARISLAVYEEf +>[subseq from] serine hydrolase n=1 Tax=Thermoanaerobacterium saccharolyticum TaxID=28896 RepID=UPI0005F01027 +--SLHDDIMNFVSNAGGDIGVSVKNLKTGERI-DINEDMMFPSASTIKILIMAQIYKMAK +EGYIRLTDNIVLSDFMKTDGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM +KNINRMAEDLGLVHTKIQRKMMDFEAA-KSGKDNYTCPKDMAHLLEQMYAGKVVDEEHSI +KMIEVLKKQQD-LGRLDMYLPDDVVIAHKPGELKH-LEHDVGIVFLKDCD-YIISVMTNN +LSTN-LDGRRAIGKISKMVYDEy +>[subseq from] serine hydrolase n=1 Tax=Pseudanabaena sp. BC1403 TaxID=2043171 RepID=UPI000CD8D601 +--------KDLAKEKDLSMQMMVVDLDSGAYA-QIGANQPIAAASTIKAPILVAFFQDVD +AGKIKLDEQLEITADVKVGEAGDFQFLPTGTISALEVATQMIVISDNTATNMIIKRLGGF +SALNQRFKSWGLNNVVVNNQLPDLEGT------NTISTQDMVSLLAMLDKGKLIEPRSRD +RFMDIMRRPIT-NTLLPKGIGEEARIIHKTGDIGS-AVGDAGIVDMPNGKRYAIAVMVKR +PDND-QRANELIRQVSRATYDYf +>[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI001445AD64 +-----NSLQTLTANSDLIPGVFLLDLDNGGYI-DINSNISFAAASTIKIPILIAFFQDVD +EGKIRLDEMLILQKEMIVGGSGNMQYQPTGSYTALDVATKMITISDNTATNMLVAKLGGQ +EALNGRFRSWGLITTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNMVSMRSRD +LILNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR +PNND-PRAAKLISSISSAAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf208 TaxID=1735679 RepID=A0A0Q4EXB0_9SPHN +--DLLNAVQALGASFKGEAGISVRDIDEGWVV-AWAGDSPRPQQSVSKFWVAIAVMDAVD +RGRLSLSDPVTVTRSDLTVHQPIRTLVGKDGTTIGELLRGAMTRSDNTCNDVLLWRVGGP +AAINRMLAEKEIAGVRFGPGERQLQARYLADPLDGASANGVTLGLSLLAQGKLLSARSTA +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS +TRQPIPVRMRLMGDVTRAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. 67-36 TaxID=1895849 RepID=A0A1M3DAN0_9SPHN +--ALVEQVDALVRGFPGVAGIAIRAVDDGWTV-ESGGRRRMPQQSVSKLWVAMTVLDQRD +SGRLKLDDPVTLYPSDLTLHQPIAALVKPSGTTVGALLTRALTHSDNTANDRLLTLVGGP +AAVRSFIERKQLGDIRFGPGERLLQSAYIADPPDGAAPLAIADALARLARGELLSETSTR +FLLTTMGSTVTGRARLKAALPPGWSLEHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TMRPMRDRQLLIQAAAGAL---- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas carotinifaciens TaxID=1166323 RepID=UPI000DD8B938 +-----RTVQTLYAGFEGKKGIAIRAVDDGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD +KGKARLDDPITVRREDLTLHQPIAYLVKGDGTTVGGLLTRALTQSDNTANDRLLTYVGGP +AAVRRMIAEKRLGDIRFGPGERLLQAAYVADPPDGAAPIAIADALARLTRGELLSETSTR +ILLETMGASRTGHARLRAAIPASWQLAHKTGTGQNAGFNDVGLLTAPDGRRFAVAVMIGD +TTEPIRNRQVLIQNVAAAVAT-- +>[subseq from] serine hydrolase n=1 Tax=Geminocystis herdmanii TaxID=669359 RepID=UPI0011819F2E +--DLKNKFAQLQTKYQLEAGAFFVDLDNGAFV-NFNGITTFSAASTIKTPILVAFFQDVD +AGKIYLDEQLATSPSNIGGGAGGMQQPVGTKYSAIHTATEMIVNSDNTATNMIIERLGGK +DELNRRFKEWGLDVTQISNLLPDLEGT------NTTSPRDLAMVLAKVNQGDLISVRSRD +RMLDIMRQTRT-RTLLPQGIEKDATIAHKTGDIGT-VLGDAGIIDIPTGKRYIGGVLVKR +PHND-YTARTLIQDISRTAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus choshinensis TaxID=54911 RepID=A0A0Q3WI38_BRECH +----EQVIQETLIDAPGVFGVAVTHLETGETA-GNLDDQLFQLASAFKIPILVTLMRDVE +EGKIRLDQRVPLKWNERVPGSGILQELDAGALTVKDLATLMTIVSDNYATDLILNLV-GL +KNVNTHMRELGLEEIHLRHTCWQLLNSMPTLDNNVATPADLNRLLVMIAKKEILTPASCD +IMLDIMRRQHY-NSRLPYLLPPGTKVAHKTGTVNE-VVNDAGIIYLPNKGAIAITVLSRG +IK-DKQAAELTIARVAKAIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E9V1C0_9SPHN +-rKLDREISRIGGTFPGHVGIAVRDIAARRTL-HFNGLQLFPQQSVSKLWVTLTALGEVD +AGQLELTEKVEIRDPDLTVHQPIRDIVRRRGTDYADLIERAITHSDNTANDRILRRVGGP +DVVQKFLDDHGLSSIRFGTDERTKQSAYLADPIDGAPPVAIVEALARLXEGKLLSGPSTA +LLLATMSRTKSGPQRLKAGAPQDWIVRHKTGTGXQSGYNDIGLFTSPDGRTYAIAVMIAR +TRVSIPERMAMMQEVVRAVVNY- +>[subseq from] Class A beta-lactamase, subclass A2 n=4 Tax=Bacteroides TaxID=816 RepID=A0A642EKK6_BACFG +---LESKIKKSIENVPAQVGVAII-INGKDTI-TVNNECHYPLMSVMKYPQALAVLHYLH +QHNQPLFTKIFIPKEALLDYSPLRDKYPGGNMPIDQLLDYTIQKSDNNACDILFNYTGGV +SYTDSYIRSLGINNFSISKTEDDMHEDLAACYENWSTPLEIASLTDMLFSKELFPTEYQN +FLKETMLNCQTGTNRLPVLLDTTARIGHKTGTSDRNGINDVGFILLPDGKRYTIAVLVKD +SKESMADTEKIIANISGIVYHH- +>[subseq from] Beta-lactamase n=2 Tax=Pseudanabaena TaxID=1152 RepID=L8N0H5_9CYAN +--ALLAKIKELAKEKDLSMQMMMVDLDSGTYV-QIGANQPIAAASTIKTPILVAFFQDVD +AGKIKLDEPLEMTADVKVGQAGDLQYLPTGTISALETATKMIVISDNTATNMIIKRLGGS +VALNQRFKSWGLNSIVINNQLPDLEGT------NTISTQDLATLLSMLDRGKLIEPRSRD +RFMDIMRRPVT-NTLLPQGLGEDARIIHKTGDIAS-SVGDAGIVDMPNGKRYAIAVMVKR +PDND-QRANELIRQISRATYEYf +>[subseq from] Putative beta-lactamase n=2 Tax=Leptolyngbya boryana TaxID=1184 RepID=A0A1Z4JC10_LEPBY +---------AIAPQTQLTPGLMVVDADTGAYF-DINGSNAIPAASTIKFPILVAFFQAVD +EGKVRLDQPLTLKKEQIAAESGDLQDQPGSQFPAIQVATKMIDISDNTATNMIIDLLGGK +EAVNQRFQAWGLTNTVIQNALPDLQGT------NTSSPRDMVTLLSAVNSGKLVSMRSHE +RMLTIMRKVVN-NSLIPQGLGQGAVIAHKTGDIGM-MLGDVGMIDLPNGKRYFMAAMVKR +PHND-DRAGDAIRKMSELTYQYf +>[subseq from] Uncharacterized protein n=1 Tax=candidate division WOR-1 bacterium RIFOXYC12_FULL_54_18 TaxID=1802584 RepID=A0A1F4T669_9BACT +--ELSQRFAALTRNHGQKVGVAFIDLKTGREL-TVNGTAEFPTASVGKVPVMAAAYALAD +KSQLNLDTKVRYLAEDRLGGSGLLQWTKCGRYSLRRLISLMITHSDNTATKMIVDNL-GL +AAINDYLRSQGLNDIVIADPT--MLREPPLPGRNLTTPLAMAHLVTRIEQRRGFSETSTA +EMLKFMRNQKY-RWGLWQGVPPGTTIADKTGNLT-GILNDVGIVYTKAGN-YVLAIFTQG +FSQK-NNARRLINQLSQAAYEEy +>[subseq from] Class A beta-lactamase n=1 Tax=Sandaracinaceae bacterium TaxID=2510337 RepID=A0A520PXB6_9DELT +--TLQGELAEIAARIDGRVAIAVVSLDRGGEW-AVNGDAPMPQQSTFKTWLAVAAADAVE +RGEASWEDEVRIERAHLLFYQPIAEEVGPEGFTLAHLVEQILLVSDNPSADAILRHLGGP +GAVQAALERRGVEGVRITTNEEGLHAAALAADPNAATALGAARSLARLARGELLSEASTR +RILSLMEASETGQARLRAGLAPGWALAHKTGSGFEVGANDIGVLTAPDGRRYAVAVFVAG +TTADAATRDGVIAGVARAVTR-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7ZMS0_9BACT +----RAHIETLIARSGADVGLAFRTLDGRDEL-LIQPDVEFHAASTMKVPVMIELFRKAR +AGALKLDDRIPVANESIVDGSPYKYKHVGGTMSYRDLCEAMITVSSNFATNLLIERL-GA +KNVQRTTESLGAPGMHVLRGVEDDK-AFRQGLNNTTTARGLMTLMEKIAKGEAVDKPSSD +EMIAILERQHF-NDRIPAGLPEGTRVAHKTGEITK-IQHDAAIVFAE--RPYVLVILVRG +LQ-DARKGSALAADISRVIYE-- +>[subseq from] Serine hydrolase n=1 Tax=bacterium TaxID=1869227 RepID=A0A2W4S861_9BACT +--SLRPALEERIARHQGVVGLAIIDLATGDTL-SIRGDEPFPTASVIKVPVLVEVFHQVE +NGRLRLEDPIVMLDVDKRPGSGVLQYLTAPLITVRDAAFLMIALSDNTATNLLVDKV-GI +RAVTARMDSLGLPRTALHSKVFDRSSSVAPDSSGVTTPNEMARLFAMIHRGEAVSPEASR +EMLRMLRAQFY-TDAIPRYLPAGTTVAHKTGSID-AARHDCGIVSSREPRDYVLCVFTKE +NQRTDNEAHVLIADLARLVH--- +>[subseq from] Beta-lactamase n=2 Tax=Labilithrix luteola TaxID=1391654 RepID=A0A0K1PTJ4_9DELT +------------------------------------------MQSVFKLPLAIELLAHVD +AGDLRLDDEVTIRPSDLRPGGALADELPNGGRSMLALLERMVIASDNTAADILLERVGGP +RKVTDRLHALGIEGVDVSRSEADLHFTYLADPRDTAKPNAMVDLLLRVHQRKVLKPESGE +RLVSILERTTTGKKRLRGLLPPETVVAHKTGMSDTAATNDVGIITLPGNGHVVIAAFLSN +SKGDDDTRDRAIATVTRAMVDHf +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium barthaii TaxID=1054037 RepID=A0A4R6FHP7_9SPHN +------VVRNLGQSFNGKVGIAVRRVGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD +RGKIRLSDSTTITRKDLTLHQPSAALVGNSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRSYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVHALAKLKENDMLSPASSQ +LLLSIMGEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTCYAVAVMIGS +TTEPIPVRWQLMQAVAKAVVA-- +>[subseq from] Uncharacterized protein n=1 Tax=Sphingobium yanoikuyae ATCC 51230 TaxID=883163 RepID=K9CUT5_SPHYA +---LVSVIQNLGQSFRGKVGIAVRRVGADWTV-AYNGNALFPQQSVSKLWVSMTFLDAVD +RGKIRLADSTTITKKDLTLHQPSAAMVGSSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKEGDMLSSASAR +VLMNFMEEAKTGPQRIKGGVPHSWTYMHKTGTGQSTGFNDVGIMTAPDGTSYAVAVMIGS +TTVSIPERWQLMQAVSRAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae subsp. rhinoscleromatis TaxID=39831 RepID=A0A378EHS6_KLEPR +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPRRRP--------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Staphylococcus hominis TaxID=1290 RepID=A0A533IUA6_STAHO +-------IRSLVADFDGLVGVAVRSVQDGWTA-SANGDRLMPQQSVSKLWVAMTVLDTID +RGRATLDSPVSITWDDLTLHQPIAALVKRDRTTVRELLGRALTQSDNTANDRLLRFVGGP +AAVRAFIERNALGSIRFGPGERLLQSRYIADPPDGASASAIAHALSQLKRGRLLSPGSTA +YLISTMESSRTGKQRLRGAVPPGWRFGHKTGTGQTAGYNDVGLLTAPDGKSYAIAVMIGD +TGRPIPARQQLMQAVVATVVA-- +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sp. LK11 TaxID=1390395 RepID=A0A1P8PU94_9SPHN +------------------------------------------------------------ +--------------------------------TAAKAMEAMIVRSDNLAADQMFATLGGP +AKVQQWVLSHNISGMRVDRTIAQLLRGHLADIKDVATPVAMVQLLRILDSGTALSSQSRA +YLLGLMRQCRTGTRRIRGLLPAGTLVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG +GR----DRQPVIAEVSRMIYDRf +>[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00132FBA02 +------------------------------------------------------------ +------------------------EKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASLQ +QLIDWMEADKVAGPLLRSALPAGWFIAYKSGAGERGSLGIIAALGPDGKPSRIVVIYTT- +----------------------- +>[subseq from] Serine hydrolase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A656PT59_9SPHN +----VSVIRSLGQSFKGKVGIAVRRIGADWTV-AWNGNSLFPQQSVSKLWVSMTFLDAVD +RGKLRLTDTTTLTRNDLTLHQPSAALVAKQGTSYSDLMRRAMTQSDNTCNDALLRAAGGP +DAVRGFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPSAIVAALAKLKQGDMLSPASTR +LLLNVMSEAKTGPQRVKGGVPAGWHYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTVPIPERWALMQAVSKAVAA-- +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas TaxID=13687 RepID=A0A0A1WCM5_9SPHN +------------------------------------------------------------ +--------------------------------TAAKAMEAMIVRSDNLAADQMFATLGGP +AKVQQWVLSHNISGMRVDRTIAQLLRGHLADIKDVATPVAMVQLLRILDSGTALSSQSRA +YLLGLMRQCRTGTRRIRGLLPAGTLVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG +GR----DRQPVIAEVSRMIYDRf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf20 TaxID=1735685 RepID=UPI0012E1C109 +--DLLNAVQALGASFKGDAGISVRDIDEGWVV-AWEGDSPRPQQSVSKFWVAIAVMDAVD +RGRMSLSDPVTVTKSDLTVHQPIRTLVGADGTTIGELLRGAMTRSDNTCNDVLLWRVGGP +DAINRMLAEKGVAGVRFGPGERQLQARYLAAPLDGASANGVTLGLSLLAQGKLLSARSTA +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAIAVMIAS +TRQPIPVRMRLMGDVTRAVVA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Pelosinus propionicus DSM 13327 TaxID=1123291 RepID=A0A1I4LZ33_9FIRM +-kELQKKIEDTLAAYTGRWGMVIQNHSNGQHF-ALNPDMVFPAASMIKIPIMYEVMRQAA +AGKIDLEQLLIVKDELRVDGAGILKERPGIAMTIRELVTLMIILSDNTATNMIIDFI-GM +STVNQTMEHLGLKSTVLRRQMMDFAAA-AAGLENETSSADIICLLTKIYDHTNLPADYGK +LMIDILSRQQV-RDKLPFFLPEEIAIAHKTGTLP-GVEHDGGILFLPGG-PYIVCIMTAD +LPAN-VEGLQLVAALGKVIYEHf +>[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc sphaeroides TaxID=446679 RepID=UPI000E46C73E +----TSQIRTLLASYTLNPGIFFLDLATGNYI-DINGEKRFAAASTIKFPLLVALFQEID +AGRIKLTDKLVMRRDLRVGEAGTMKKPIGTKFSVLQTATLMMTISDNTATNLILDRLGGA +AKVSQRFRSWGLQNTAMQNLLPDIPGK------NTTSSKDLVRLAALVYNNRLLSPNSRN +QVLGIMRRVKT-NTLLPAGIGKGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR +PNHD-PKAGDFVREVSRRVYNY- +>[subseq from] Beta-lactamase n=1 Tax=Synechococcus elongatus (strain PCC 7942 / FACHB-805) TaxID=1140 RepID=Q31MT6_SYNE7 +---LQTQLAALIQQQALKAELFLTDLDTGNYV-DINGTTSIPAASTIKIPVLAALMEAVQ +QGKVRLDEQLTMTQDLVASEAGAMQYPVGSKFTVLETAIEMIRISDNTATNLLIARLGGI +EAVNQRFAAWGLQTTRIRNLLPDLEGT------NSTTPKEMVELLAKVENGSLLDPRSRD +RFFAVLRTTET-NTLLSRGLGEEATIAHKTGDIAM-VVGDVGLIDMPSGKRYIAAMLVRR +PDND-LKANELIRQVSQRTYQ-- +>[subseq from] FRAMP1.1 beta-lactamase n=1 Tax=Prevotella sp. CAG:255 TaxID=1262923 RepID=R5CTW4_9BACT +-----AAIKKLAEGKDAEIGVAWME--GNAMH-SMNNERLYPLMSVFKLHVAVALLKDME +RRGAAVDTTLNITPEQMRKYSPLMKQHPDGRITLPQLIRYAIAESDNNAADILIAMAGGI +DSVDREIHAMGIKDCHLSETEATMYEAPINSYANWSKPESVVWLLRKLYDGRLLSGEYDR +CIKQALAATTTGADKIKAGLSQGMTLAHKTGTGFKMADNDAGVVTMPDGRQVAIAILIKD +SKMSDADNARLMAEITKIIL--- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D6KNL3_9SPHN +--ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD +AGRLDLGEMVRIRPGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP +AAVQDFLDTHGLSSIRFGTXERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS +LXLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLIXSPAGRTYAXAVMIAR +TREPTPVRMEMMQEVVRAVVRY- +>[subseq from] serine hydrolase n=1 Tax=Pseudanabaena sp. 'Roaring Creek' TaxID=1681830 RepID=UPI0006D8272E +--ALLAKIKELAKEKDLTMQMMIVDLDSGTYV-QLGANQPIAAASTIKTPILVAFFQDVD +AGKIKLDEQLEMTADVKVGQAGELQYLPTGTISALETATKMIVISDNTATNMIIKRLGGA +VALNQRFKSWGLNSIVINNQLPDLEGT------NTISTQDLATLLSMIDRGKLIEPRSRD +RFMDIMRRPVT-NTLLPQGIGEDARIIHKTGDIAS-SVGDAGIVDMPNGKRYAIAVMVKR +PDND-QRANELIRQISRATYEYf +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium faniae TaxID=570446 RepID=A0A1G4SD41_9SPHN +-----SVIRNLGQSFNGHVGIAVRRIGADWTV-AHNGNQLFPQQSVSKLWVSMAFLDAVD +RGKLRLSDTTTITKKDLTLHQPSAMLVDNSGTTYSNLMDRAMKQSDNTCNDALLRAVGGP +DAVRGFLARRFISNIRFGPGERLLQSNYLANPPDGAAPSSIVRALAKLKEGDMLSPTSTR +TLLSIMGEARTGPQRIKGGVPAGWSYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS +TTEPIPVRWQLMQAVAKAVAA-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A348V185_9BACT +----SRQILQRISSFRGETGLVVKDLQTGWTF-LHNDEALFPAASLIKIPIMVACFKAVE +EGRLSLAEKYVLRRQDRVGGSGLLRRMRNGRFTYEELIDYMVTHSDNIATNVIIKRL-GF +DYISQVFEELGLRDTVLNRQMMDFRAR-ENGLENYTSAREMADLLEQIYHGRCLNAAISE +RCLDVLKRQKI-NDRLPRFLPREATVAHKTGQERE-VCHDAGIVFSPHGD-YIIIVLVRT +WTGP-LTTKTFIARLSSYFYQVf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. CCH5-D11 TaxID=1768786 RepID=UPI0008315B49 +--ALEASISQLVREFPGIAGVAVRAVDEGWTV-EAGGRRPLPQQSVSKLWVAMTVLDQRD +SGRLRLTDAVSLTPADLTLHQPSAFLVRNGITTVSDLLFRALTQSDNTANDRLLTLVGGP +SAVRAFIERKQLGEIRFGPGERLLQAAYIDNPPDGAAPLAIADALARLARGELLSETSTR +LLISTMESSRTGRARLKAGAAPGWTLAHKTGTGQNAGFNDVGLLTAPDGRRYAVAVMIGD +TQRPMRDRQQLIQAVAATVT--- +>[subseq from] CubicO group peptidase (Beta-lactamase class C family) n=1 Tax=Sphingobacterium composti Yoo et al. 2007 non Ten et al. 2007 TaxID=415956 RepID=A0A5S5CZU6_9SPHI +---LQKRIAKLFAQYKGRFAYAMVDMQTGEQL-LHRATETFHAASTMKTPVMIEVFRQAA +AGKFRLTDSITVYNESIVDNSTYAYARIGTKLTWYDLVYRMITESSNLATNILIDRV-GA +KNIMKTMKSLGLKDIQVLRGVEDTK-AFEKGLNNTTTAYDLMLLFKQLAEGKAVSPASSE +AMIAILKDQHF-RSMIPARLPKDVRVAHKTGSIA-GIRHDSGIVYLPDGRAYVLVLLSGE +LED--SDARDALAAMSRVFYDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. OV641 TaxID=1881068 RepID=A0A1H7ASM1_9SPHN +--ALEASISQLVREFPGIAGVAVRAVDEGWTV-EAGGRRPLPQQSVSKLWVAMTVLDQRD +SGRLRLTDAVSLTPADLTLHQPSAFLVRNGITTVSDLLFRALTQSDNTANDRLLTLVGGP +SAVRAFIERKQLGEIRFGPGERLLQAAYIDNPPDGAAPLAIADALARLARGELLSETSTR +LLISTMESSRTGRARLKAGAAPGWTLAHKTGTGQNAGFNDVGLLTAPDGRRYAVAVMIGD +TQRPMRDRQQLIQAVAATVT--- +>[subseq from] Beta-lactamase class A n=1 Tax=Roseibium hamelinense TaxID=150831 RepID=A0A562TGX9_9RHOB +--TLRSEVSRIAETVGEGVGASIAFPGEPPID-LINGDRSFPMMSTVKTLVSMAALDRVS +EGEMTLESQITIMEDDLSVMSPVNLTFPQAPTTLYNLIWTAIVDSDNTTPNTMMRVMGGP +ESVEAFVREQGVDEISVARNLNGLFVPLWDDPRDTTTPNAMARLLSGFLAGDVLDEERTA +ILIDIMEQTRTGKARLQGMLPPGTIVGHKTGTGHD-SINDAGWIRLPDGRTMVIAVYNRN +TA-SIEAKEQVIAQIARAAYD-- +>[subseq from] Serine hydrolase n=1 Tax=Altererythrobacter sp. TaxID=1872480 RepID=A0A2E1Y6P4_9SPHN +--ALQQQLGDLGEAFNGDVGIAVTQADTLATM-SYTGTKRFPQQSVSKLWVSLTALDLRD +EGALDLSEPVTLRAEDLTVHQPLRDIVRARGTDYADLINRAITQSDNTANDRLLRRVGGP +SAVEGFLRRNQISGVQFGTDERTKQSAYLADPIDGASPVGITKALARLARGDLLSENSTG +LIVSTMQRTRSGPRRLKGGVPAGWTIAHKTGTGQQSGYNDIGILTAPDGTNYTIAVMIGS +TRASYAARMGMMQEVTRSVVRY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520IF48_SPHSX +--DLLNAVQALGASFKGQVGITVRDIDEGWVV-AWDGDTRRPQQSVSKLWVAIAVMDAVD +RGQISLSDRVTLTRADLTLHQPIRALIGADGTTIEELLRGAMTRSDNTCNDVLLWRVGGP +AAINRMLDAKGVEGVTFGPGERVLQARYLAAPYDGASANGVTLGLSLLAQGKLLSARSTA +SLLTLMRSSKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDIGLLVAPNGHRYAVAVMIAS +TREPIPVRMRLMGDVTRAVVA-- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A3B9ZY15_9BACT +-----AGLENASASYRGKVGIYLKDLHTGKFW-EYNPDRLFPSASLIKVPIMAAAFEKIK +AGELTLDTQIKLTRQDRWGGSGSLKWVREGTLSVMEIIYKMITESDNTATHMLIDYL-GF +DFLQMEFSRLGLVYTKIYPEGLNLTSG-RVARENYTTAREMADLLEQIYEGKLIDKNSSE +QMLEFLKHTKS-RSRLRRGLPLGWEIGHKTGLLRR-SCHDVGIVFSPRGD-YIIAVLTSD +VP-NYSSAKNFIDKVAKVTYKYy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534HHC1_9GAMM +-hKLETEVREIDARLDAVMGVAIEDLSNGGTL-FLNPDEIFPQASSIKIAVLAELYHQHQ +EGKLKLDDLYTVNTADLVADSNIMGGLTPGVITNRGLATMMIAVSDNSATNVLIDRI-GM +ENVNALLESLGLHHVRLQRKMMDLRAAVEG-RENVATPREMMTLLDALYRNKVLNPGLTD +DFFKMLSTPK--DSWIPRYLPEDVKIANKPGSLE-GVRTDSGVIFAK--RPYILCVMTTY +LR-NERDGEEAIAQLSRAAYRTf +>[subseq from] Serine hydrolase n=1 Tax=Pseudanabaena sp. TaxID=1153 RepID=A0A2W7A5P4_9CYAN +-----SKIKELAKEKDLTMQMMVVDLDSGAYV-QVAANQPISAASTIKTPILVAFFQDVD +AGKIKLDEMLEMTADVKVGEAGDFQLLPGTKIPALEVATQMIVISDNTATNMIIKRLGGF +AVLNQRFKSWGLNNIVVKNQLPDLEGT------NTISTQDMVSLLAMLDKGKLIEPRSRD +RFMDIMRRPVT-NTLLPKGIGEDARIIHKTGDIGS-VVGDAGIVDMPNGKRYAIAVMVKR +PDND-QRANELIRQISRTTYDYf +>[subseq from] Uncharacterized protein n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1PPK1_9ZZZZ +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPKR----------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium Pan44 TaxID=2527983 RepID=A0A517SJY1_9BACT +--RWKDRIRELAAAHKGKVAVAVSHPSSKETF-FLNEKEVMPTASLIKLAVMVEAYRQAD +AGRIDLKKLATLKEEDKVPGSGILTQHFSAGLSVRDSVRLMMAYSDNTGTNLVLDAI-GI +PATAKAMEELGYPETKIHSKVRDLSVRSVKYGLGSTTAADMVSILERLLKGELANEESTK +AMIAHLRSNPD-KETFSKHLPATAKYGYKGGAVDR-IRTAAGFIDVEGG-PLLVAVLTAE +NTDQENSAQNLIARITKEAFDRf +>[subseq from] serine hydrolase n=1 Tax=Sediminibacillus massiliensis TaxID=1926277 RepID=UPI0009884D02 +--SLQMKLEQTLERIEGEVGVTVEHLQTGEHA-SINGDRLYQTASTIKVPILCALYKLAE +QGLIGLEERVRIENEDFVPGSGVLQEMQPGLVTVKDLATLMIVVSDNLATDKLLTMI-GM +EKVEGFMRSQSLQSTFVRQSIWELLCQRDVKDNNLMSPNDMAHLLRKITDHEGLAADSCN +QILDIMSRQHF-QNRIGGELPPQVKVASKSGSLFQ-VANDVGIVYLPDG-SYTISVFTTG +IQP--KEQDNAIASISKVVFDHf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9RE75_9BACT +-qKLQVSIAGTDRELDGILGVSIQDLSSGEQF-SLHGDEVFPQASSIKIAVLAELYRQAA +QGKLKLTDLYTVNSADLVVDSYIMNGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GI +ENVNALLDSLNLPHTRLRRKMMDIKAA-AEGRENISTPNEMAGLLRAVYQKKFFDAALTE +DLFKVLSTPK--DSWIPRELPDDLKIANKPGSLE-GVRNDSGIIFLANR-PYILCVMTTY +LRR-ERDGEQAISRISLAAWRMf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520ELL1_SPHSX +-----NAVQALGASFKGEAGISVRDIDEGWVV-AWAGDSPRPQQSVSKFWVAIAVMDAVD +RGRLSLSDPVTVTRSDLTVHQPIRTLVGKDGTTIGELLRGAMTRSDNTCNDVLLWRVGGP +AAINRMLAEKEIAGVRFGPGERQLQARYLADPLDGASANGVTLGLSLLAQGKLLSARSTA +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS +TRQPIPVRMRLMGDVTRAVVA-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium minihomine TaxID=2045012 RepID=UPI000C76C813 +----EQMLREYLNAQPGEAAVWVQDLTDGTTA-VINADAVFPSASTIKLVIMACLLEKVR +DGQMSLDDLVTMTPDMKTGGDGILKELRSGHIALEELLTLMIIVSDNTATNILIDRL-GM +EEINSTANALGMKQTVLERRMMDSQAK-KLGKDNFTCARDLALILEKIYREQCVDASMSR +LMMDLLKRQQQ-TGRLQLYLPEDLEIAHKCGDLDY-LEHDVGIVFLPKH-PYLIVVLTKD +NP-TNKEGRELIGIVSKIVWEQ- +>[subseq from] Metallo-hydrolase family protein n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A522CLW8_9CAUL +--ALQSRLDVLAAGYGEDVGIAVTDVTSGWTA-GVGQDRLYPQQSVSKLWVAIALMRAVD +EGRLDLNAWLTMDDADRSVFQPVVAEYRQGSTPMSDLLRRALVESDNAANDRLMRELGGP +EGVRAALDDMGLTNVKVGAYERDLQAAYVAAPLDGASPAAITAALAALSRGALLSEESTL +RITALMTAARTGPRRLKGGLPAGWSIAHKTGTGQQGGINDVGLLTAPDGRTYAVAVMLPR +TRHSVTARLAFMQSVSRAVVEQw +>[subseq from] Beta-lactamase n=1 Tax=Nostoc linckia z16 TaxID=1628751 RepID=A0A2C6V676_NOSLI +---LSSQIRTLLANYSLNPGIFFLDLATGNYI-DINGEKRFAAASTIKFPLLVALFQDID +AGKIKLTDKLVMRRDLRVGEAGTMQKPVGTKFSVLETATLMMTISDNTATNMVLDRLGGA +AKVSQRFRSWGLQNTAMQNLLPDVGGT------NTTSSKDLVRLAALVANNRLLSPNSRN +QVLGIMRRVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR +PNYD-PKAGDFVREVSRRVYNY- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A649W1R7_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-HYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEMHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLITAIPGDPRDTTSPR--------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Carboxylesterase, beta-lactamase family n=1 Tax=Synechococcus sp. (strain JA-2-3B'a(2-13)) TaxID=321332 RepID=Q2JKE0_SYNJB +--ALQERLAALADQPGLTAGALFWEVETGAFA-GVRPDQAFPAASVIKIPILLAFFQAVE +TGQVRLDEQLTLREDLKGGGAGVLQTRPLGSVSALEAATLMITLSDNFATNLIIDRLGGQ +ETLNQKFRQWGLQHTQISWWLPDLEGT------NTSSPRDMVWLLSQVEQGRMLNRRSRD +RFLDILWRTQR-LSYFRPNLGQEVRIAHKTGTLGS-VVGDAGILDLPNGRRYVAAVWVKR +ETPNDPRAEGLIASLSQAAYEFw +>[subseq from] Serine hydrolase n=1 Tax=Alphaproteobacteria bacterium PA2 TaxID=2015570 RepID=A0A257J1R0_9PROT +-eALQRDLDSLAEAFGETVGLAIVDISANWMV-DVRGDEAFPQQSVSKLWVALTTLSAID +RGAAGLDDAVVLTESDRSVNQPVSYLITPEGTTVEDLLRRALIESDNAANDKLMALAGGP +GAVRRLLHEKGLEGIALAEDERHLQAAYLSRPYDGARPGSVAVALGRLQAGKLLSKESTR +WMLDTMARATTGPNRLKGGLPDGWRIAHKTGTGQQGGINDVGLITAPDGRTYAVAVFLQR +THNPVSERLAFMQAVSQALVAHw +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter gaetbuli TaxID=266952 RepID=UPI001360E777 +-kALQDRLAAIGKAFPGEVGIAVVDVSSGARM-HFEGRKPFPQQSVSKLWVAMTALDLVD +QGALDLAEPVSIERRDLTLHQPIREIVRTRGTDYFDLFERALTESDNTANDRLLRRVGGP +TAVDGFLRREGIIGVQFGPDERTKQSKYLADPVDGASAIGIAQALARLAKGDILSPASTS +FILGTLERTKSGPNRLKGGTPAGWVMAHKTGTGQQSGYNDVGVLRAPDGSQYAIAVMIGR +TRSSFSSRFEMMQAVTRAVADH- +>[subseq from] class A beta-lactamase n=1 Tax=Bacteroidaceae bacterium TaxID=2212467 RepID=UPI0012B84D46 +-tAIEQKILQAIQGKNATVGAAFSI--DGQLF-TFNDEHRYPLMSVFKLHVAIAALQKME +NECIAPDSLRFIESLQIHKYSPLRELYPERNLSYADLMRYAVSQSDNNACDILIDYLGGI +DIVKDRIDKLGITNYNLTETEETMHSRISNCYNNWSTPSSTLQLLEKLYNEPILNETHTE +FLKNILIETSTGKDKIKAGLPDNIALGHKTGSSDKIGDNDTGVIYLPNGKLCFLAIFIKD +SRESDQTNAQIIADIARIIYN-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Bathyarchaeota archaeon TaxID=2026714 RepID=A0A2E8ED93_9ARCH +-------LNDAVSGLKGTLGVSVKHLETGETA-SINGGDLFPTASVFKVPVIIEFFRQLE +SRTVSLDEKKMLAEADKVPGSGILKELSNGLLTYGDLLRLMMILSDNTATDLVIKRV-GK +DRVNATIRSLGLEETKVVADCRDILFSLGVDENDVTTPSEMLRLLEMIVEGKAASRESCN +EIMEIMSKCQTGGNRIPKYLPAEMELTHKTGSLP-GIRNDAGLVTIQTGERYILSCFIKG +AA-DVYAAEETIAMVSKSVYKYf +>[subseq from] Serine hydrolase n=1 Tax=Altererythrobacter sp. TaxID=1872480 RepID=A0A2E6K8U3_9SPHN +--ALQQQLGDLGEAFNGDVGIAVTQADTLATM-SYTGTKRFPQQSVSKLWVSLTALDLRD +EGALDLSEPVTLRAEDLTVHQPLRDIVRARGTDYADLINRAITQSDNTANDRLLRRVGGP +SAVEGFLRRNQISGVQFGTDERTKQSAYLADPIDGASPVGITKALARLARGDLLSENSTG +LIVSTMQRTRXGPRRLKGGVPAGWTIAHKTGTGQQSGYNDIGILTAPDGTNYTIAVMIGS +TRASYAARMGMMQEVTRSVVRY- +>[subseq from] class A beta-lactamase n=1 Tax=Larkinella soli TaxID=1770527 RepID=UPI0013E2DAF6 +------------------MGISIKGFEKEDTI-NINANDTFPLMSVFKFHIALAVLQRVD +DGVLKLTQKVLVEKSQLHSWSPMRDQYPHGQLSLDEILRYTVSNSDNNGCDILLNLIGGA +KGLQKYIRSLGADDFTVSVNEFQMRS-WENSYLNYSTPMETTKLLEKFYNGLILKANSTD +YLYRLMVETTRGTRYMKSGLPQAAEIAHRPGLSGRIAMNDVGIVKLPNGQYFIISIFLKD +IMQDDRQAEEFFSEVARLTWEYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium limneticum TaxID=1007511 RepID=A0A5J5I719_9SPHN +------VVRNLGQSFRGKVGIAVRRIGADWTV-AWNGTSLFPQQSVSKLWVSMTFLDAVD +RGKLRITDTTTITRNDLTLHQPTAALVAQNGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRSFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSR +LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTVGIPERWALMQAVAKAVVA-- +>[subseq from] serine hydrolase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=UPI000262C200 +---LVSVIQNLGQSFRGKVGIAVRRVGADWTV-AYNGNALFPQQSVSKLWVSMTFLDAVD +RGKIRLADSTTITKKDLTLHQPSAAMVGSGGTTYSDLMRRAMTQSDNTANDTLLRAVGGP +DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKEGDMLSSVSAR +VLMNFMEEAKTGPQRIKGGVPHSWTYMHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTVSIPERWQLMQAVSRAVVA-- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8ZUQ9_9BACT +---LRERLTKIAASFPGKVGIFVRNIETGEET-GVNPNDEFPMASTYKVAIMVQVFREAD +AGHLSLAERVPLSDADRRLGSGLLPYMTPGLPTIHDLVLLMITLSDNEATDLMLKRV-GA +RNVTAMLRQLGIQDMRVDRSTEELIGAFVDDARDHTSPKAMAELLTKIFRAEAATEKSCH +DMLEIMEQQQL-RTRIHRYLE-NTTVASKNGTIGY-VTNDVGIVSVGKH-HLVVSAYTLK +ANVTTEQAEELIGRLARAAYSYf +>[subseq from] Serine hydrolase n=1 Tax=Calothrix elsteri CCALA 953 TaxID=987040 RepID=A0A2A2TG31_9CYAN +------QIRGLLASYSLNPGIFFLDLQTGNYI-DINGEKRFAAASTIKFPLLVALFQEID +AGRIKLTDKLVMRRDLKVGESGTMQYKPGTKFSVLETATLMMIISDNTATNMVLDRLGGT +TKVNQRFRNWGLPNTAVRNQLPDIAGK------NTTSSKDLVRLAALVHNNRLLSSNSRN +QVLGIMRRVKT-NTLLPAGIGKGATIAHKTGTLRF-IIGDAGIIDMPNGKSYLAGVLVQR +PNHD-PRAGAFVREVSRRVYNY- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. KVJ20 TaxID=457944 RepID=A0A1E2WIQ0_9NOSO +----SSQIRALLATYSLNPGIFFLDLDTGNYI-DINGEKRFAAASTIKFPLLVALFQEID +AGRIKLTDKLVMRRDLRVGEAGTMKKPVGTKFSVLQTATLMMTISDNTATNMVLDRLGGV +AKVNQRFRGWGLQNTAMQNLLPDIPGK------NTTSSKDLVRLAALVSNNRLLSPNSRN +QVLGIMRRVKT-NSLLPAGIGKGATIAHKTGTLRF-IIGDAGIIEMPNGKSYLAGILVQR +PNHD-RRAGDFVREVSRRVYNY- +>[subseq from] Uncharacterized protein n=2 Tax=Sphingomonas sp. Leaf230 TaxID=1735694 RepID=A0A0Q4IWD7_9SPHN +--------------------------------------------------LAAMLLAKAD +AGQIDLRETLHWTKEDMLSVSPVTTVNLGKGLSVQELARAALVTSDNTAANVLMRRFGGP +SQLTAFWRSIGDKSSRLDRYEPELNVTPPGTDLDTSTPAAMAATTAAIVHGTILTADSRA +MLRAWMAEVKTGQDRIRSGFPTNWISGDKTGTGIKHIYVDLAFGGPAGRSPLIVTAYFEP +ARPMARDAVAVLATVGRIAA--- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E0WY21_9PLAN +--DLASELTALAESHDGDVAIALKYLPTGESF-AYRADVPMPTASLIKLPLMATVYHAVD +AGRLDPQQMLTLAEEDKVPGSGILTEQFSPGLSLHDAIHLMIRHSDNTATNLVAGAV-GL +AETAKYMEELGMPETKLHRDTSLFPERSQQYGLGSTTAADQVKLLELLATGQLVSPKSSE +AMLAHLYACED-DSKLARSLRDGLKIAHKTGAVNK-VRTDAALIDLPGGR-LAICVLTAN +NAGDKNAAEILCGRIARRAVRHf +>[subseq from] Serine hydrolase n=1 Tax=Nostoc punctiforme NIES-2108 TaxID=1356359 RepID=A0A367R3E4_NOSPU +----TSQIRTLLASYTLNPGIFFLDLDTGNYI-DINGEKRFAAASTIKFPLLVALFQEID +AGRIKLTDKLVMRRDLKVGESGIMQYKPGTKFSVLETATLMMTISDNTATNLVLDRLGGA +AKVSQRFRSWGLQNTAMRNLLPDIGGT------NTTSSKDLVRLAALVSNNRLLSPTSRN +QVLGIMRRVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR +PNYD-PKAGDFVREVSRRVYNY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas ginsenosidivorax TaxID=862135 RepID=A0A5C6UI35_9SPHN +--QLAATIDALHRGFAGKAGIAIRAVDEGWTV-EAGGRLSLPQQSVSKLWVAITLLDLRD +QGKARLDEPILVRPEDLTLHQPIAMLVKGAGTTVGDLLTRALTHSDNTANDRLLTFVGGP +GAVRAMIERKRLGDIRFGPGERLLQAAYVANPPDGAAPIAIADSLARLARGELLSETSTR +ILLDTMGASVTGRARLRAALPPGWTIQHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMVGD +TLRPIRERQQLIQSVAAAVAS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=T1Z0T9_ECOLX +------------------------------------------------------------ +----LLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGSGAFRPGPPASWVCGIKTRPAANGTTNDIAVIWPKDRAPLILVH---- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Larkinella terrae TaxID=2025311 RepID=UPI0012AD8416 +-qSLSEKLTAYLQQLQARVSVAFESLTDHSAF-AHRADELVPSASVIKIPILIETMERVK +SGQFDLEKIHMLQASEKTGGSGVLQTYPDQSLTNREVLTLMMTRSDNTATNILIREL-GM +ENINQRMRTLGLTQSQLNRMMMDTLAA-KLGRENRVTAFEMNALLKKIYRHEVATPALCE +QMIDILKRNTD-QTTFRLFLPKSAVIAHKTGELSY-VRGDAGIFYVS--KPFLLSVFVQG +TT--TPEAEKIIGEIAQICYQQy +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter lutipelagi TaxID=1964208 RepID=UPI0010F6969C +---FEQRIAQLANGSDGRIGVYAMDLSTGQEI-GILADQRFPMASTSKVAIAATYLAGVD +NGRWSLTSEFRLPR------------R-GGGVPAHTLLDLMISKSCNDCTDALLSAVGGP +SAVNAWMRNAGIGGFQLNRDIATLIRASRVDSRDSATPRAMGQLLAGIHQGRWLSASSRR +VLLNAMAETTTGKNRMRSALPMHANLAHKTGTLSR-TASDIGIFYTPDGRAIAAAIYVTG +QSPSLA----------------- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacterales bacterium 68-7 TaxID=1895737 RepID=A0A1Q3JFC7_9PROT +--RLRREIPEIAKRCPGVLGVAIGASRGGDLY-TFNAARSFPMGSVFKAMLGAAVLSESE +AGQFALSETVEVRDIDLSPHSPVADAWPATTYTLDDLLKRTVSDSDNTAADILLKRIGGP +GMLTAWLESKGSEGLRVDRYEREMQPAFLIDPRDTATPSGMMNWLDGLAAGLLLSPAATT +RLLKMMTETPRASGRLAAATPAGAELAHKPGTGWNLATNDVGVYTLKDGRQLTVVAFLAG +ATLDETGRDKAIADVGRAAI--- +>[subseq from] Serine hydrolase n=1 Tax=Cylindrospermopsis raciborskii CENA303 TaxID=1170769 RepID=A0A1X4GA50_9CYAN +----KTTIENLSAANNLIPGVFIVDIDSGAYV-DVSGNKNFPAASTIKIPVLVAFLEDVD +RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIEVATKMMTISDNTATNILISKLGGK +ELLNARFRSWGLVNTAIQSPLPDLEGT------NTTSPKELASLIAKVNQGELISMRSRD +LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR +PH-NEPAAAKLINSISQATYSY- +>[subseq from] Serine hydrolase n=2 Tax=Bacteria TaxID=2 RepID=A0A534HZ32_9GAMM +-hKLETEVREIDARLDAVMGVAIEDLSNGGTL-FLNPDEIFPQASSIKIAVLAELYHQHQ +EGKLKLDDLYTVNTADLVADSNIMGGLTPGVITNRGLATMMIAVSDNSATNVLIDRI-GM +ENVNALLESLGLHHVRLQRKMMDLRAAVEG-RENVATPREMMTLLDALYRNKVLNPGLTD +DFFKMLSTPK--DSWIPRYLPEDVRIANKPGSLE-GVRTDSGVIFAK--RPYILCVMTTY +LR-NERDGEEAIAQLSRAAYRTf +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. BK235 TaxID=2512131 RepID=A0A4R2PG13_9SPHN +---LLNAVQALGGAFRGQVGISVRDIDEGWTV-AWGGDSARPQQSVSKLWVAIAVMAAVD +AGKLSLDDAITVRRSDLTLHQPIRAKVGAAGTTIGELLRGAMTHSDNTCNDVLLWRVGGP +IAVRRLLRDKGIEGVTFGPGERLLQARYLAAPYDGASANGITLGLSLLAQGKLLSARSTA +SLLALMRQSRTGPLRLRSGLRPGWTLAHKTGTGQATGYNDVGLIVAPDGHRYAVAVLIAS +TREPIPVRMRLMGDVTRALVA-- +>[subseq from] Putative beta-lactamase protein n=1 Tax=Stanieria sp. NIES-3757 TaxID=1807358 RepID=A0A140KB26_9CYAN +--SLKSKLQTLASQYKLQPAIFLVDLDDNSYV-SIQGAVTIAAASTIKLPVLVAFFQDVD +QGKIHLDEKLTMNKEDIGSGSGGMQEKPGTQFTALEVASQMITISDNTATNMLIKRMGGA +EQLNQRFLEWGLTQTVIRNPLPDLEGT------NTTSPEDLGNLLINLERGKFVSLKSRD +RMLKIMSNLAR-NTLLPIGLETNATIAHKTGDIRS-VLGDVGIIDMPNGKRYVASVLVKR +PDND-PKAKEFIQKMSQVAYQH- +>[subseq from] serine hydrolase n=1 Tax=Myxosarcina sp. GI1 TaxID=1541065 RepID=UPI000907A803 +--ALQAQLEDLAAQYQLEPKVFLADLDTQSYV-SIDGQTPLSSASTIKLPILIAFFQDVD +AGKIDLQEELTITEEVVGGGSGGMQYPIGTKYTALETVTLMITVSDNTATNMLIERLGGQ +AALNQRFIDLGLTATRLQNPLPDLTGT------NTTSTEDLGNLLVQLARGELVSIQSRD +RLLLIMRSIVR-NTLLPEGLEAGAIIAHKTGDIKS-VLGDAGIIDMPNGKRYIASVLVKR +PDND-PQAKEFIQQMSHLVYQYf +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacF n=2 Tax=Planctomycetes bacterium TBK1r TaxID=2527963 RepID=A0A518KXW4_9BACT +-dDLARRITPLISDYQGDVAVGIKNLSGEGEF-WYRHDQPMATASLIKLPLLVATYQQID +SATVDPAQLIELTREDQVPGSGILSQHFSPGLPLIDAIRLMIRYSDNTATNLVIDQV-GL +PTTTESMKSLGLVHTQLHAKVYRRDTAPKRSQRGSTSAADMIKLLEGIHTHQVASKTSCE +AMIGHLLSCDD-QVKLAAGLPSGTKIAHKTGGVSS-VRTDAGIIFGPGEQAFAICVLTEN +NKSADSAPHRLIADIGRAAYQAf +>[subseq from] Uncharacterized protein n=1 Tax=Clostridium sp. CAG:299 TaxID=1262792 RepID=R6Z6E6_9CLOT +--EMKQDICAFLQGKQGKVCVSFYDLNAGEGF-SIRGTERVPSASTIKLVILAEAMRRVR +EGELSLEQTITVTEEMRTGGDGILKELLPGHFTLREILTLMIIVSDNEATNILIRML-GM +DSVNRMASELGLKEACLGRLMMDSEA-KKQGKDNYICADDMTEIFRQIYAGQCVGEEESR +LMMDILKRQQQ-GGRLQLYLPEEIETAHKCGDLD-ALENDGGIIFLPGR-PYILTVLTSE +ME-SNKEGREVIGHISRIVFD-- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X2Y4_9BACT +---LSETLKKLCDTVGGKVSVAVVHVETGKLA-TVDASNELPLFSVFKLPLAITVLKRVE +EGSLKLDQNVHIGPDELIVGTRANSQRWQNPFTIKQLLEFSIIESDNTSSEKLLQLVGGP +QAVTERMLSFDLQQINIKTTIRDYVAT--RSNPNTGSAAALVKLLSKLQNGELLQRAQTD +LVIGMMERAKTGLHRLRGNLPQGTKVGDKTGSGDPNSTNDVGLITLPNGGHLAMAVLLHE +STLSDEAQEKLIADLARTAFDAy +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Butyricimonas virosa TaxID=544645 RepID=A0A413IPU7_9BACT +--GLEEQLRKVIANKKAQIGIAVI-INSKDTI-TINNDARYPMMSVFKLHQALAVADYCE +KKGLSFDTSIYIRKADLKTYSPLRDLYPDGELPIKELLEYTLHLSDNNACDILFLQTGGT +EATDHYIRTLGMRHFAIKATEDEMHQDKNKCYLNWSTPLETVRMIELLLNVPLFDDEYQK +FIKTTMMSCETGKDRLARPLQNKAILGHKTGTGDRNGMNDVGFVYLPDGQSYTIAVFIKD +SEESEAATARIIADISKTVYRH- +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sartorii TaxID=671267 RepID=R9IDW2_9BACE +-kAIENALQEYIKGKDARIGVAVI-INGKDTA-SVNGNRDFPMMSVVKFPLALTVAHWID +TNGMSLNDSITFRKNDLDEYSPMLKKYGKSRMTVRELLEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFNRFDAEMRNTSLSYS +VIATMLEQCRTGIDRLVALLSSDATIGHKTGTGFISAINDCGYVNLPNGVRYSIAVFVAD +SGYDMARTSAIIAEISRIVW--- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1J4A0_9ZZZZ +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEVIPNDE---------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_2_20CM_2_66_4 TaxID=1803462 RepID=A0A1Q7AH46_9BACT +----RAHIETLIARSGADVGLAFRTLDGRDEL-LIQPDVEFHAASTMKVPVMIELFRKAR +AGALKLDDRIPVANESIVDGSPYKYKHVGGAMSYRDLCEAMITVSSNFATNLLIERL-GA +KNVQRTTESLGAPGMHVLRGVEDDK-AFRQGLNNTTTARGLMTLMEKIAKGEAVDKPSSD +EMIAILERQHF-NDRIPAGLPEGTRVAHKTGEITK-IQHDAAIVFAE--RPYVLVILVRG +LQ-DARKGSALAADISRVIYE-- +>[subseq from] class A beta-lactamase n=1 Tax=Alistipes communis TaxID=2585118 RepID=UPI0002E7B0D1 +---LERDLCRAVRGVDAEVGIAVVR--EGRVIaSVGGDRPMPAMSTFKFPLALAAAARLD +SLGLPLSAQLEVTGDDLWPWSPLREAHPAGGFSFGELLRYTVAESDNCACDRLIREIGGI +GALQRYVEGLPAEGLDFRMTEREMSGAPDAQRRNRATPEAMALLLDRFRHDSLFASEYRD +FLWQTLCTTTTGMNKLRAGLPDGTTIGHKTGSSDRDADNDLGYVELSDGSGYAICVYVAE +TALSDGETAALIAEISRLVWQ-- +>[subseq from] Uncharacterized protein n=3 Tax=unclassified Elusimicrobia TaxID=1797919 RepID=A0A1F9QU62_9BACT +--AMVASLENLAYNYSGHVGIYIKDLNSDKVW-EYNPDRLFPSASLIKVPIMIAVCDKIK +RGELSLDTQIKLTRRDRAGGSGSLKWVREGTLSVMEIIYKMITESDNTATRMLLDYA-GM +DYFQRAFEQMGLVYTKIYPEGFSLTSGWVA-RENYTTAREMAGLMERIYKGEVVDRNLSE +FMLEVLKHNKS-RSRLRKGLPLGWEIGHKTGLLRR-SCHDVGVVFSPRGD-YLISVLTSE +VP-NYSSAKGFISSVAKLTYKYy +>[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013DF5B2C +------------------------------------------------------------ +--------------------------------------------SDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGAALI--- +>[subseq from] ClassA n=2 Tax=Bacteria TaxID=2 RepID=A0A127SAZ6_9BACT +------------------------------------------------------------ +-------------------------------MTIREICDAAVRQSDNTAGNLQFTLLDGP +NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLALNLKEYATGDILSDDKKE +IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRNDIAIVTPPNKKPIFVAVLSKK +AEQDAEYDNKLIADATKIIFD-- +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium KOR34 TaxID=1938618 RepID=A0A5C5VHS6_9BACT +--SFEASLTELLEGHRGTVAAAAKHLPSGKEF-RFNADQPMPTASLIKLSIMAAAFKAEA +DGRLKMSDEVSLKEEDKVPGSGVLTENFSAGMPLHDAIRLMIAFSDNTATNLVIDQV-GL +PATTEYMEELGLPSTRLHAKVFRRDTSIAPERSGSTTASEMIELLEQINDRKLISSQASE +AMYQHLLACES-RSKVPRYLPEDTPVAHKTGSVS-AARCDAGIIESPKG-PIAFCILTGD +NKGDENEAELLAAEFGKAIYTHy +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9MWU2_9BACT +-qKLEASIAEVDHNLDGVMGVAIEDLTSGQKY-QLRENEVFPQASSIKIAVLAELYRQAQ +QGKLKLTDLYVVKSVDLVGDSPIMNGLTPGVVTLRDLATMLAAVSDNSAANILIDRL-GM +ENVNSLLDSLGLTHTRLRRKMMDLKAAG-EGRENISTPGEMMTLLDAIYRGKVLNKSLTD +DFFKLLSTKKN--SWIPRDLPENLKIADKDGELE-GVRNDSGVIFLENR-PYILCVMTTY +LRRE-RDGEEAISKISV------ +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. ZDH117 TaxID=2305907 RepID=A0A396RV78_9SPHN +---LVETVRFLGREFEGRVGIAIRRVDTGWSV-DWQGDLPMPQQSVSKLWVAMTALDARD +KGMLRLDQPVTVTRSDLTLHQPIASLVKGDGTDPDELLRRAMTMSDNTANDKLLSLAGGP +AAVNRFLAGKGLTGIKFGPGERLLQAAYVANPPDGATANGIARALAKLHRGELLKPDSTA +YLLRYMEESKTGRARLKGAMPPGWRLAHKTGTGQTAGFNDVGLITSPDGTTYAVAVLIGR +TGKPVRDRQSLIQAVATTLIA-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. S-NIH.Pt15_0812 TaxID=1920129 RepID=A0A430BMR5_9SPHN +------------------------------------------------------------ +---------------------------------AAKVLEAMIVHSDNVAADQLFAALGGP +AAVQQWVWSQKIIGMRVDRTIAQLLRGHLADSKDVATPVAMVQLLKALDSDTVLAPQSRS +FLLGLMAKCRTGTRRIRALLPAGTVVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG +GN----DRQPVIAQLSRMIYDRf +>[subseq from] Beta-lactamase n=1 Tax=Sphaerobacter thermophilus (strain DSM 20745 / S 6022) TaxID=479434 RepID=D1CAH8_SPHTD +--AARTELDDLIRRAPGTVGLVIEDLTTGERL-EWSPETQFLAASIIKIPILVEGLRQAE +EGTVRLDQMVPVPDDAKVGGFGILKELTSVTISLLDLLTLMIIVSDNTATNLCIDVL-GV +ESINRTIASLGLTGTQLQRKMMDYEA-RDRGLENFTTPADVARLLRLIATRQILTPEACD +LALDIMARQQV-RDRLPLYLPDDMRVAHKTGELS-GVRHDAGVIFFESG-PVIVVALTQG +FSDQGGDASALIAQIPRVL---- +>[subseq from] Uncharacterized protein n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1JX38_9ZZZZ +------------------------------------------------------------ +-------------------------------------------MSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEVDKVTGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Scytonema tolypothrichoides VB-61278 TaxID=1233231 RepID=A0A0C2LL52_9CYAN +--QLSSQLKTLIARYSLSPGMFFLDLDTGNYL-DFNGEKIFPAASTIKFPILVALFQEVD +AGRVKLNETLVVRRDLKAEGSGVLQKPVGTKLSVLDTATKMITISDNTATNMIIDRLGGI +AKLNQRFRSWGLQNTVIRRQLGDFKGT------NTTSPKDLVRLSALVANNKLLSSTSHS +QALGIMRRVEN-KRLLPAGLGKGAVIAHKTGTLGV-LLGDAGIIELPSGKRYLAGILVKR +PFGD-KRARDFISQVSKLVYG-- +>[subseq from] Putative Beta-lactamase n=1 Tax=Bacteroides finegoldii DSM 17565 TaxID=483215 RepID=C9KU58_9BACE +-----------------------------------NNDIQYPLMSVFKFHQAVALADYMD +KKRLPLGTLLSIKKSDLKPYSPLRDQFPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP +DSVNRYIQSLGIRDCEITHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRRKTLFDEAYKN +FIYQTMVECQTGQDRLVALLGKGVTVGHKTGTGDFNGCNDIGFVLLPNGHAYSIAVFVKD +SAESSLKNSKIIADISRIVYKY- +>[subseq from] Uncharacterized protein n=2 Tax=Prevotellaceae TaxID=171552 RepID=A0A0M0N1Z8_9BACT +-----AAIKKLAEGKDAEIGVAWME--GNAMH-SMNNERLYPLMSVFKLHVAVALLKDME +RRGAAVDTTLNITPEQMRKYSPLMKLHPDGRITLPQLIRYAIAESDNNAADILIAMAGGI +DSVDREIHAMGIKDCHLSETEATMYEAPINSYANWSKPESVVWLLRKLYDGRLLSGEYDR +CIKQALAATTTGADKIKAGLSQGMTLAHKTGTGFKMADNDAGVVTMPDGRQVAIAILIKD +SKMSDADNARLMAEITKIIL--- +>[subseq from] Penicillin-binding protein, transpeptidase n=2 Tax=Lyngbya sp. (strain PCC 8106) TaxID=313612 RepID=A0Z083_LYNSP +--TVKQQILALTENSDLKPGILLVDLDTGGYV-DINSESAFAAASTIKVPILVAFFQAVD +EGKISLNEVLTMEGQHIAGGSGDMQYQPSGTYTALETATKMIVISDNTATNMLIERLGGA +EFINQKFLDWGLHNTVIRDVLPDLRGT------NKTTPKDLVNLLTQLNQGGLVSMKSRD +RIFRIMEKTEN-DSLLASGLGRGATIAHKTGNLKS-VSGDVGLIDLPNGKRYLLAVLVER +NDED-SAAESLIRNISQTVYESf +>[subseq from] serine hydrolase n=1 Tax=Sphaerobacter thermophilus TaxID=2057 RepID=UPI00069026B2 +--AARTELDDLIRRAPGTVGLVIEDLTTGERL-EWSPETQFLAASIIKIPILVEGLRQAE +EGTVRLDQMVPVPDDAKVGGFGILKELTSVTISLLDLLTLMIIVSDNTATNLCIDVL-GV +ESINRTIASLGLTGTQLQRKMMDYEA-RDRGLENFTTPADVARLLRLIATRQILTPEACD +LALDIMARQQV-RDRLPLYLPDDMRVAHKTGELS-GVRHDAGVIFFESG-PVIVVALTQG +FSDQGGDASALIAQIPRVL---- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9F9Y6_9BACT +-qKLEATIGGVDHNLDGVLGVAILDLATGQKY-VLHADAVLPTASSIKIAILAELYRQAQ +QGKIKLSDLYTLQSSDLVGGSGIAGALTPGVLTIRDVAALMISVSDNSATNIIIDRV-GM +ENVNTLLDSLGLTHMRLRRKMMDVKAA-AEGRENIATPREMVQLLEDLYRGKVLNKQMTE +DFFAILSVHKE--SYIPRELPEDLRIANKPGELE-GVRNDSGIVFTGNH-PFVISVMTAY +LRRE-KDGGDAIIRIATAAYQMf +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas TaxID=13687 RepID=A0A654DHI4_9SPHN +--DLLNAVQALGASFKGQVGITVRDIDEGWVV-AWDGDTRRPQQSVSKLWVAIAVMDAVD +RGQISLSDRVTLTRADLTLHQPIRALIGADGTTIDELLRGAMTRSDNTCNDVLLWRVGGP +AAINRMLDAKGVEGVTFGPGERVLQARYLAAPYDGASANGVTLGLSLLAQGKLLSARSTA +SLLTLMRSSKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDIGLLVAPNGHRYAVAVMIAS +TREPIPVRMRLMGDVTRAVVA-- +>[subseq from] serine hydrolase n=2 Tax=Sphingomonas TaxID=13687 RepID=UPI001443B383 +--DLLNAVQALGASFKGQVGITVRDIDEGWVV-AWDGDTRRPQQSVSKLWVAIAVMDAVD +RGQISLSDRVTLTRADLTLHQPIRALIGADGTTIDELLRGAMTRSDNTCNDVLLWRVGGP +AAINRMLDAKGVEGVTFGPGERVLQARYLAAPYDGASANGVTLGLSLLAQGKLLSARSTA +SLLTLMRSSKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDIGLLVAPNGHRYAVAVMIAS +TREPIPVRMRLMGDVTRAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter lutimaris TaxID=1538146 RepID=A0A395LG17_9SPHN +---LDDRLFAIGSDFAGKVGIAVHDPARGRMM-HFNGTDLYPQQSVSKLWVALTALDQAD +RGRLDLSETGTVRREDVAVYSPIRGGVVANGTSWRDFMKRAITASDNTANDMVLRRVGGP +DAVRATLARKGFSDIRFGPGERPMQSDYVDDPVDGATPVAIAAALGELHEGALLSEAGTQ +QFLEWLGQVKSGPNRLKGGLPAGWSIGHKTGTGQQAGYNDVGILTAPDGSVYTVAVLVGR +TQVPIPARMEMMHAVVRAVAG-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7ZNU1_9BACT +----RAHIETLIARSGADVGLAFRTLDGRDEL-LIQPDVEFHAASTMKVPVMIELFRKAR +AGALKLDDRIPVANESIVDGSPYKYKHVGGVMSYRDLCEAMITVSSNFATNLLIERL-GA +KNVQRTTESLGAPGMHVLRGVEDDK-AFRQGLNNTTTARGLMTLMEKIAKGEAVDKPSSD +EMIAILERQHF-NDRIPAGLPEGTRVAHKTGEITK-IQHDAAIVFAE--RPYVLVILVRG +LQ-DARKGSALAADISRVIYE-- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas aerolata TaxID=185951 RepID=A0A2T4YP51_9SPHN +--DLLNAVQALGASFKGQVGITVRDIDEGWVV-AWDGDTRRPQQSVSKLWVAIAVMDAVD +RGQISLSDRVTLTRADLTLHQPIRALIGADGTTIDELLRGAMTRSDNTCNDVLLWRIGGP +AAINRMLDAKGVEGVTFGPGERVLQARYLAAPYDGASANGVTLGLSLLAQGKLLSARSTA +SLLTLMRSSKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDIGLLVAPNGHRYAVAVMIAS +TREPIPVRMRLMGDVTRAVVA-- +>[subseq from] serine hydrolase n=1 Tax=Weissella cibaria TaxID=137591 RepID=UPI00143F48C7 +------------------------------------------------------------ +-------------------------------------------MSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPRLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGAS----- +>[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. IB2014 016-6 TaxID=2517818 RepID=A0A5C8Q036_9ACTN +------------------------------------------------------------ +---------------------------ATTGMTVADLCDASLTVSHNTATNLPLDLLGGP +TAVTAFAPGLDDATTRFDRNEPQLNSTGPDDERDTTTPAAIVESMRAVPLGGGLQPADCE +RLTTSLVANTTGDATIRAGVPAGWLIGDRTGTGAQGERNDVGIVLPPDRAPLV------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Desulfovibrio sp. An276 TaxID=1965618 RepID=A0A1Y4D2C1_9DELT +--EIAPTLADLERRFACDISLAALDVQGGQKV-LYRADNRFAFCSTFKFFLVAEVLRKAD +ADRSLVGKRLFWKENEEQEWSPATRGRGGEGMSVIALCEAAMTLSDNTAANLLLRLLGGP +FAMTKCMRALGDRDFLLCDYEPRLNYENRLPQANTATAAGFLQAMRTLLFDRSYPDFSRN +LLLQLAGKTRTGTGRIQASLPKGATLFHKTGTGF-GNVHDLALVRYPNGRECLLVIFTKN +TQNVEKEDQ-------------- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPLOWO2_12_FULL_59_9 TaxID=1797952 RepID=A0A1F9VP73_9BACT +---MIASVQERIQRNPGKVGIYIKDLRNDRVW-TYGENEMFPSASLVKLPIMATVFQRVQ +EGKLSLDKRIAVNRRYRMGGSGRLKWFRDGSFTLRDVIQWMITESDNTAMKMAIDTV-GF +AAFQEELPRFGFRATQVNPEGLSLSSG-RVSRENYTTAAEMGMFLEKLYRKELVSPTASE +IMTELMKKLPT-RKRLATGLPYGWQIAHKTGLLRQ-ACHDVGIVYTPEGD-YIICVLTGK +NS-SYRRAKELIASVGKTMHQYf +>[subseq from] Serine hydrolase n=1 Tax=Peptoniphilus sp. HMSC075B08 TaxID=1739525 RepID=A0A1F0GQW5_9FIRM +-rRLENTIENIVEESSANISVSFYDLDQGEGF-SINGDKRVPSASMIKLLILLKALDECD +KGKINLEDTINLDDHDKVDGSGILKELSNNHFSIRELLTLMIIVSDNTATNILIDLL-GM +EEINKIGNDLGLEKTSLERKMMDSNAR-EKGLDNFTSSNEILKLLKMIYDKDFVSEDFSD +LALDILLRQKE-RQRLQRYLPEDLKIASKSGDLDN-LENDGGIFFTENK-NYILVVLVNQ +AK-SNVLAKEIIGEISLKIYK-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacteria TaxID=2 RepID=I1V598_9BACT +------------------------------------------------FMAASAILKQSE +TQTELLTRRISLKKSDLVNYNPITEKHLDTGMTIGELAAAALQYSDNTAMNKLIEQLGGP +QKVTAYARTLGDNTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHATLGTALAEPQRA +QLVEWMKGNTTGGMSIRAGLPATWVV---------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Stanieria cyanosphaera TaxID=102116 RepID=UPI0012375CED +--SLKSKLQTLASQYKLQPAIFLVDLDDHSYV-SIQGSGAIAAASTIKIPILVAFFQDVD +QGKFRLDQELTMNKEDIGSGSGSMQEKPGTQFTTLEVATKMITISDNTATNMLIKIMGGA +EKLNQRFLEWGLTETVIRNPLPDLEGT------NSTTPEDLGNLLINLERGKLVSLKSRD +RMFTIMSNLVR-NTLLPVGLEADATIAHKTGDIRS-VLGDVGIIDMPNGKRYVASVLVKR +PDND-PQAKEFIQKMSQVAYQH- +>[subseq from] Beta-lactamase, putative n=1 Tax=Acaryochloris marina (strain MBIC 11017) TaxID=329726 RepID=B0CCE0_ACAM1 +---IKRQIQAWAAQSELKPAMFFLNPSTGEYL-DINGAKSISAASTIKIPVLLAFFEDVD +AGIIDLDEPLVMRPDLVASEAGSMQEPVGTTFSALDTAEYMIAISDNTATNMLIDRLGGA +EKLNQRFKSWGLKHTTIRNPLPDLEGT------NTISPQDMAALMLKLKDEDLLSSTSRE +QALDILRQTVT-NTLLPQGIEKDADIAHKTGDIGS-VVGDIGLIDMPNGQHYVAAILVQR +PHND-PRAQELIRKISKLTYKTf +>[subseq from] Uncharacterized protein n=2 Tax=Pelosinus sp. UFO1 TaxID=484770 RepID=A0A075KJX0_9FIRM +-eELRKKIEHVLARYTGRWGIVIQSHTTGESV-EINPEMIFPSASMIKVPILYEVVRQTA +SGLISLDESLVVTDHFRTGGAGILKERPNISMTVRELLTLMIILSDNTATNMLIDLV-GM +DSVNKTMKDLGLGQTVLRRRMMDFEAALAG-KENDTSAADLAHLFSIIYGNSKLPTEYSE +LMLDILTRQQV-QDKLPFYLPEETVIAHKTGTLS-GVEHDGGILFLPGG-PYIICILTAD +LTVN-FQGLQLVASLGKEIYDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Larkinella arboricola TaxID=643671 RepID=A0A327WPN0_9BACT +----------------VQVSVAVEELEGKTQF-YHRADERPPAASVIKVPIMVETMEQVK +TGQFDLEKIHILQDAEKTGGSGILKTYPDQSLTNREVLTLMMTHSDNTATNILIREL-GM +DNINQRMRSLGLTRSQLNRVMLDTMA-VKQGRENRVTAREMNALLRKIYRKEVATPALCD +QMIEILKGNRD-QKTFRMFLPPSAVIAHKTGELTY-VRGDVGIFYV--RKPFLLSVFVQG +TT--TEDAERIIGEIAQICYNQf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8HPF0_9BACT +-eHVQRQLRDVASSFDGVMGYYVVDLTDGRTF-GALQDDVFPTASSIKLALIYELFKQVD +EGRIALEDVRPLNPAFKVGGSGVLHELTTPSLSIRDYATLMVVLSDNTATNVLIDAV-QM +TRVNDRMTALGLGHTKLRRRMMDREAALRGD-ENVSTPAELAKLLQIMYRGDGLTPGSRD +TLIAILKKSKD--TPLRRGVPPNVDVANKPGDLE-GVATDAGIVYVKNR-PYVLAVMTSY +AN-DGGGGARAIEAASRAVYDYf +>[subseq from] Beta-lactamase n=2 Tax=Raphidiopsis TaxID=244599 RepID=A0A1Z4VBW5_9CYAN +----KTTIENLSAANNLIPGVFIVDIDSGGYV-DVSGNKNFPAASTIKIPVLVAFLEDVD +RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIEVATKMMTISDNTATNMLISKLGGK +ELLNARFRSWGLVNTAIQSPLPDLEGT------NTTSPKELANLIAKVNQGELISMRSRD +LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR +PH-NEPAAAKLINSISQATYSY- +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Prevotella sp. MGM2 TaxID=2033406 RepID=A0A2L2WWK4_9BACT +---LQAKIEEVIAPYDAKIGVAVIV-NGLETT-TVNNTADYPLMSVMKFHQALAVANFLQ +HEDGQITDKIYITPEQLLPWSPLRDQYPGGGVSIGDLLRYTLQQSDNNACDILFNLIGGP +RYVNRYIRSLGLRQTVITATEAEMHASEKACYANRTSPLDAARLLERFETRMLFSHDVQS +LIRRLMITCQTGMDRLPLPLETKAVIGHKTGTSDWTGTNDIGFVRLPSGQRYVIAVFVKD +SAEAPVTNARIIADISRTVFEH- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. YG1 TaxID=2082188 RepID=A0A2Z6AFN8_9SPHN +------VVRNLGQSFRGKVGIAVRRIGADWTV-AWNGTSLFPQQSVSKLWVSMTFLDAVD +RGKLRITDTTTITRNDLTLHQPTAALVAQNGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRGFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSR +LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTVGIPERWALMQAVAKAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. AAP5 TaxID=1523415 RepID=A0A4P6XB01_9SPHN +------------------------------------------------------------ +---------------------------------AAKVLELMIVRSNNQAADQLLAAVGGP +AAVQQWLSSQNIIGIRVDRTIDQLLRGHLADIKDVATPVAMVALLHKLDSGAVLTAQSRA +FLFELMRRCETGTRRIRAMLPAGTPVEDKTGTLD-GVTNDVGFITMPDGHRVAVAVFARG +GR----DRQPVIAAVARVIYDRf +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Melainabacteria bacterium GWA2_34_9 TaxID=1801604 RepID=A0A1F6PJI3_9BACT +--KLTNQLKYLAAAYQLNAGIFVWDYNTGGYV-DINGDGVFPTASIIKLPVLFQVFRRAE +KGLINLNDKISLTNYYITGGSGALQYSPGRKLTYRQLASLMIQESDNTATNMLLSSVGGM +NELDREIKSWGLKTTSLSNWLPDLDGT------NVSTPKEMGTLLYNIGNTNLLSIKTRA +EIVDIMSHVRN-RNLIQAGLPADVGFIHKTGDIGT-MLGDAGVVALPDGRKYVIVIMVKR +PWNS-FAAKEFIIEASKITYNSy +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' 210A TaxID=2014529 RepID=A0A235ICB1_9NOSO +----TSQIRTLLASYSLNPGIFFLDLDTGNYI-DINGEKRFAAASTIKFPLLVALFQEID +AGRIKLTDKLVMRRDLKVGESGIMQYKPGTKFSVLETATLMMTISDNTATNLVLDRLGGA +TKVSQRFRSWGLQNTALRNLLPDIGGT------NTTSSKDLVRLAALVSNNRLLSPSSRD +RVLGIMRHVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR +PNYD-PKAGDFVREVSRRVYNY- +>[subseq from] Beta-lactamase n=3 Tax=Erythrobacter TaxID=1041 RepID=A0A165QDN7_9SPHN +---LERQIAQLADGSNGRIGVYAIDLATGREI-GVLADQRFPMASTSKVAIAATFLAGVD +AGKWSLTSEFRLPR-------------PGGAMPAHRHLSLMISKSCNDCTDALLNAVGGP +RAVNKWMQEAGIEGFQLSRDIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSDYSRR +VLLDAMEETTTGKRRMRSALPLSANLAHKTGTLAR-TASDIGIFHTPDGRAIAAAIYVTG +QSPSMA----------------- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter flavus TaxID=192812 RepID=A0A222ERW3_9SPHN +---LERQIAQLADGSNGRIGVYAIDLATGREI-GVLADQRFPMASTSKVAIAATFLAGVD +AGKWSLTSEFRLPR-------------PGGAMPAHRHLSLMISKSCNDCTDALLNAVGGP +RAVNKWMQEAGIEGFQLSRDIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSDYSRR +VLLDAMEETTTGKRRMRSALPLSANLAHKTGTLAR-TASDIGIFHTPDGRAIAAAIYVTG +QSPSMA----------------- +>[subseq from] PenP, beta-lactamase class A n=1 Tax=Nostoc sphaeroides CCNUC1 TaxID=2653204 RepID=A0A5P8VUR0_9NOSO +----TSQIRTLLASYTLNPGIFFLDLATGNYI-DINGEKRFAAASTIKFPLLVALFQEID +AGRIKLTDKLVMRRDLRVGEAGTMKKPIGTKFSVLQTATLMMTISDNTATNLILDRLGGA +AKVSQRFRSWGLQNTAMQNLLPDIPGK------NTTSSKDLVRLAALVYNNRLLSPNSRN +QVLGIMRRVKT-NTLLPAGIGKGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR +PNHD-PKAGDFVRELSRRVYNY- +>[subseq from] Beta-lactamase n=1 Tax=Cylindrospermum sp. NIES-4074 TaxID=2005457 RepID=A0A1Z4QRN8_9NOST +---LEPQIKALMSRYSLQTGMFFLDLDNGNYL-DIGGDRVFPAASTIKLPILVAFFQDLD +AGKVSLNKQLTMRGDLVASGSGIMQERVGKKYTALETITKMIVISDNTATNMIIDYLGGT +ARLNQRFRTWGLKNTVIRNLLGDFRGT------NTTSSRDMARVLALLVNDKLVSSQSKE +QALDILRQTKT-RTLLPAGLGKDALISHKTGDIGF-LIGDAGFITMPNGKHYLAAIYVKR +PYKD-VRGRNFIRQVSQLVYNY- +>[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. OK042 TaxID=1884381 RepID=A0A1I4CU21_9BACL +---WQQVIQETLIDAPGVFGVAATHLETGETA-GNLENELFQLASAFKIPILVTLMRDVE +AGKITLDQRVTLKWEERVPGSGILQELDAGALTVKDLATLMTIVSDNFATDLILQLV-GL +DNVNAHMRELGFSQIHLRHNCWQLLNSQGTLENNVATPAELNRLLVMIGKKEILTPASCD +LMLDILRRQHY-NSRLPYLLPPGTKVAHKTGTVNE-VVNDAGIIYLPDNKGAIAVTVLSR +GIKDKQAAELTIAKVAKAVYD-- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A2D8MAT4_9SPHN +---LGQRISQLAEGSQGRIGVYAIDLTTGHEI-GVLADQRFPMASTSKVAIAATYLAGVD +AGKWSLTSEWRLPR-------------PGGALSGKQHLDLMISKSCNACTDALLNAVGGP +KAVNDWMRSAGITEFQLTRDIATLVRASAVDFRDSATPRAMGQLLAGIYQGKWLSASSRG +VLMNAMRATTTGKKRMRSALPTSAGLAHKTGTLAR-TASDIGIFHTPDGRAVAVAIYVTG +QSPSMAV---------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Barnesiella sp. An22 TaxID=1965590 RepID=A0A1Y4GQL6_9BACT +--AARQQIETLLQDKKATVGVACSI--DGDDF-ALNDTVRYPLMSVFKLHVAVAALQRME +AEGTRLDEALTIDSTQMHRYSPLLGLYPSGNISYTDLLHYALALSDNNACDILIDYAGGI +GAIKHCIDRAGITGYDLAETEASMHADIPACYRNWAHPSSVVQLLQKILDGSLLNEEHTR +FMRTTLVETSTGLNKIRAGLPPEIVLGHKTGSSGTIADNDASFFCLPDGRLCFLVVLVKD +SRESETTNAALIARIARIVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf412 TaxID=1736370 RepID=A0A0T0Q060_9SPHN +---LQYRVDQLLRQFPGKAGAAIVAVDEGWSV-SSGGTLSLPQQSVSKLWVAMTVLAQRD +AGRLRLDDPVVVTRDDLTLHQPIASLVRGDGTTVGALMTRALTQSDNTANDRLLTFVGGP +SAVRAFIAEKRLGAIRFGPGERLLQARYVDNPPDGAAPLAIADALARLARGELLSETSTR +LLLETMGASRTGRARLKAATPAGWELAHKTGTGQNAGFNDVGLVTAPDGRRYGIAVMIGD +TTAPMRTRQFLIQNVASAL---- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. BK235 TaxID=2512131 RepID=UPI0010432A98 +---LLNAVQALGGAFRGQVGISVRDIDEGWTV-AWGGDSARPQQSVSKLWVAIAVMAAVD +AGKLSLDDAITVRRSDLTLHQPIRAKVGAAGTTIGELLRGAMTHSDNTCNDVLLWRVGGP +IAVRRLLRDKGIEGVTFGPGERLLQARYLAAPYDGASANGITLGLSLLAQGKLLSARSTA +SLLALMRQSRTGPLRLRSGLRPGWTLAHKTGTGQATGYNDVGLIVAPDGHRYAVAVLIAS +TREPIPVRMRLMGDVTRALVA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Root241 TaxID=1736501 RepID=A0A0Q8XN82_9SPHN +---LVTSLDGITRNFNGLVGVAVTSIEDGWTAsNVTASRPLPQQSVSKLWVTMTVLDAVD +RGVLRLDDPLTITRADFTLHQPVAALVKGDASTVGEIMRRAMQMSDNTCNDKLLHLVGGP +QAVRDFIARKQLGTIRFGPGEKLLQAAYVKDPPDGAAPASIANALARLYRGELLSANSTA +WLLATMDGAKTGKARVRGAVPPGWLYGHKTGTGQTAGFNDVGILTAPDGRSYAVAVMIGD +TSRPIRERQLLMQAVARAIVAH- +>[subseq from] Beta-lactamase n=1 Tax=Rippkaea orientalis (strain PCC 8801) TaxID=41431 RepID=B7JVX1_RIPO1 +---LKAKLDKIATQSKLKPQAWFMDLDNGAYV-SVNGSVPVPAASTIKIPVLVAFFEALD +AGKIHLDEILIMDKAIITSGAGNMQYPPGTKFTALETATQMIVISDNTATDMLIRRLGGK +EALNARFRDWGMTNTVINNRLPDLEGT------NTTTPEDLSKLLARIERGEVLTLRSRD +RLLGIMQETRT-RTLLPQGLEKDAIISHKTGDIGS-IIGDAGIIDIPNGKRYIGAVFTSR +PYND-PMGRALIQDFSRTTYQHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Cytophagaceae bacterium TaxID=2026729 RepID=A0A4Q3NX30_9BACT +--RLTQELMRLSDMSGGKVGICATHIETGKTI-TQNGKEGFPMASSYKVAIATQLLTRVD +SGSLTLAQLIPITKDDFHPGSGMLPNSPNSDLSVRSLLEFMLLISDNSATDICLRLAGGP +AAVNACMKRMGIEGLRVDRPTAWLIAAFEKDPRDTSTPEAMTLLLTKLYTQPVLKPASQA +LILDIMKRCETGLARLKGALPPDTEVLHKTGTIGL-TASDVGIIILPGN----------- +----------------------- +>[subseq from] HGE-1 beta-lactamase n=1 Tax=Brachyspira sp. CAG:484 TaxID=1262759 RepID=R5HGE6_9SPIR +---LSFKLRRYTWQKDYRIGIAVLKNDKIWTI----GTQKQPLLSVFKYFIAVEVLNKLN +KQKIDLNTKLTIKETMINKYSPMLKKYKSFPITIAELLEYTISESDNNASDILLEYIGGA +RKLDKVLKDTGFSGIEISVNEKEMNSDINKQYLNQATPKDVAKYMKTVRETDILTVEHKN +FLDKIMEKTVTGEDKIKKGLPPGTVFGHKTGSSSRDADNDAGYVILPNGETYYIAVFISN +SKLSDKENAEIIANISKTVYKH- +>[subseq from] serine hydrolase n=1 Tax=Sciscionella marina TaxID=508770 RepID=UPI000369F9CB +---LRARLAAIAHTTEAQVGVSVQNLAAGQRI-EFRARTRMPSASVIKLPILAELLRMAE +RGELSLAERVRVDRSDVVGGTGQLQEKLPQDVSLHRLARYMIIYSDNTATNLLIDRI-GF +GPVNALIRSLGLHATVLQRKMMDTEAQ-QHGKENYLDAADIAKLLRALWDGRLLAGPARA +IALGFLRDQRL-NELIPAALPPGAPVAHKTGTLDDLVTHDAGYYLVPGSE--VLVVFTTR +GT--TAAGTDAVHRMARAVWD-- +>[subseq from] serine hydrolase n=1 Tax=Sphingobium TaxID=165695 RepID=UPI000E72EFF1 +------VVRNLGQSFRGKVGIAVRRIGADWTV-AWNGTSLFPQQSVSKLWVSMTFLDAVD +RGKLRITDTTTITRNDLTLHQPTAALVAQNGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRGFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSR +LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTVGIPERWALMQAVAKAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter zhengii TaxID=2307003 RepID=A0A418NQ63_9SPHN +-eELSETITGIAEEFGGTMGIAVVDVDTGWST-GYNENDWLPQQSVSKTWVTLTALTMAE +KGLLDLDAPIRVSREDLTLHQPMRKEILRDGTTVGELIERAIQQSDNTANNAILQRVGGP +RAVRAMLREQGLDGIRFGPGEKPMQSSYLDDPVDGAKPIGIARALAAVERGEVLSKERAE +ELLTIMSNTRSGPRRLKGGRADGWVVSHKTGTGQQSGYNDVGVLFAPDSSAYAVAVMIGV +TKRPTIERMQMMQQVTRAVIA-- +>[subseq from] BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A0A0R1G2_STAAU +------------------------------------------------------------ +----------HINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Serine hydrolase n=1 Tax=Parabacteroides sp. CH2-D42-20 TaxID=2320086 RepID=A0A3L7Z8N4_9BACT +--TIENALQEYIKGKDARIGVAVI-INGKDTA-SVNGNRDFPMMSVVKFPLALTVAHWID +TNGMSLNDSITFRKNDLNEYSPMLKKYGKSRMTIRELLEWSLIESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS +EISVMLEQCRTGLDRLALLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD +SNYDIATTSAIIAEVSKIVLE-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium 13_1_20CM_4_56_7 TaxID=1803434 RepID=A0A1Q7V8I0_9BACT +-qKLESSIREVDHNLDGVLGVAIEDLTTGQKF-FLHEDELFPQASSIKIAVLAELYHQAQ +SGKAKLSDLYTISSSDLVPDSDIMLGLTPSVITNRDLATMMVAVSDNSATNVLIDRV-GM +ENVNALMDSLGLTHTRLRRKMMDVKAA-GEGRENISTPREMMSLLEQIYRGKVLNKEMAA +DFLKMLSTHKQ--SFIPRDLPDGVRTANKPGELE-GVRNDSGIVFAQNR-PYVICVMTTY +LH-TEHDGEDAIARISSAAYRMf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf10 TaxID=1735676 RepID=A0A0Q4DM65_9SPHN +--DLLNAVQALGAGFEGQVGISVRDIDENWVV-DWQGDTPRPQQSVSKLWVAIGVMDAVD +RGRLSLADPVTVTRADLTLHQPIRTLVGKTGTTVGDLLRGAMSRSDNTANDVLLWRIGGP +AAVNRMLKDKGVAGVRFGPGERQLQARYLDAPLDGASANGLTLGLSLLAQGRLLSDRSTA +SLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS +TRLPIPARMRLMGDVTRAVIA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5M9S3_9BACT +--DFANRILSVEERTGARIGVAALDTASGKRL-DYRSEERFPMCSTFKFLAAAAVLKRVD +EKQDQLDRFIRYAAKDILEHAPVTKAHLVDGMTLGALCAAAIEQSDNTAGNLLLDAIDGR +AGLTNFARNLGDNVTRLDRKEPELNSAIPGDERDTTSSAAMC------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. Leaf26 TaxID=1735693 RepID=A0A0Q4IQL2_9SPHN +------VVRNLGQSFRGKVGIAVRRVGADWTV-AWNGTSLFPQQSVSKLWVSMTFLDAVD +RGKLRITDTTTITRNDLTLHQPSAALVAQNGTSYSDLMRRAMTQSDNTANDTLLRAVGGP +EAVRSFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSR +LLLSIMSEAKTGPQRIKGGVPHGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS +TTVAIPERWALMQAVAKAVVA-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. C11 TaxID=1178594 RepID=UPI00140D20EC +--SLQAQLEDIVKDANGTFGVYVKHLETGETA-SIYENRLFQAASTFKVPILSALYREAK +KGTVNLDERVKLTEKDFVPGSGIFQRLTPGVVTIKDLAMMMIIVSDNAGTDKILEII-GK +ETVDQFMKELGLTNIHTPLTCWELLCFQESIHNNVSSPKDMAKLLELIVTKQLISEKACD +EMFDILSKQQH-RNRIPYLLPGNTVVAHKTGTVGS-VINDVGIVKLPYQGTYVITVFSTG +NS-SEAEGANIINKLSKAAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6BDB0_9BACT +-kKLETRVEEIAARLDGVMGVAILDLTDGRIL-LRNADRVFPTASSIKIAILLELYRQDQ +KGKAKLNELYTFDPKDLVEDSQIMAGLTAGMVTNRDLAQFVVAVSDNTATNVLIDRV-GM +QNVNATLRNLGLTKTMLRRKMIDIAAARRG-DENVSTPQEMARLLEMIYKGKALNKELTD +QLIKQLKTLKK-DSYLSYELPTGVDIADKPGSLE-GVRNDSGIIFAQNR-PFAISVMTAY +DR-DEKAAERAISEVALEAYHYf +>[subseq from] serine hydrolase n=1 Tax=Leptolyngbya ohadii TaxID=1962290 RepID=UPI000B59E501 +---LVARIQPLTKDLDLTPGVFLADLDNGNYY-SLNGTATFAAASTIKVPLLIAFFQDVD +AGKIRLDETMIMLQNDVAGGSGDMQFEVGTEFSALEVATNMIVISDNTATNMVIRRLGGI +EAVNQRFKEWGLEQTIVRNLLPDLEGT------NTTSPKELAAVMSLLSQGELLSLKSRD +RAIEIMQGTLT-DTLLPTSIGPGATIAHKTGDIGS-LVGDTGLIDMPSGRRYAITAMVKR +PHND-DRAQELIRQIAATAYDY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf30 TaxID=1736213 RepID=A0A0Q4K1W5_9SPHN +-----NAVQALGASFKGQVGITVRDIDEGWVV-AWDGDTRRPQQSVSKLWVAIAVMDAVD +RGQISLSDRVTLTRADLTLHQPIRALIGADGTTIDELLRGAMTRSDNTCNDVLLWRVGGP +AAINRMLDAKGVEGVTFGPGERVLQARYLAAPYDGASANGVTLGLSLLAQGKLLSARSTA +SLLTLMRSSKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDIGLLVAPNGHRYAVAVMIAS +TREPIPVRMRLMGDVTRAVVA-- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Candidatus Bathyarchaeota archaeon TaxID=2026714 RepID=A0A497L7A8_9ARCH +---LLERIREAAEGFEGVLGVSVKHLGTGEAA-SLNGGELFPTASVFKVPVIVALYRQVD +AGAVSLDEKVVLREEDKVPGSGILKELSPGLITLRDLVTLMMIVSDNTATDLVVERV-GL +ENVNATLQRLGLERTRVVADCRDILFSLGVENNDVTTPDEMLRLLEMIVEGEAASRESCD +AILETMSRCQTGSYRIGKYLPEKMEIAHKTGSLP-GIRNDAGVVTLDSGERYIISCFT-- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI0014477E96 +-----NSLQTLTANSDLIPGVFLLDLDNGGYI-DINSNISFAAASTIKIPILIAFFQDVD +GGKIRLDEMLILQKEMIVGGSGNMQYQPTGSYTALDVATKMITISDNTATNMLVAKLGGQ +EALNGRFRSWGLITTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNMVSMRSRD +LILNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR +PNND-PRAAKLISSISSAAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas yabuuchiae TaxID=172044 RepID=A0A147IWE2_9SPHN +--DLLNAVQALGAGFEGQVGISVRDIDENWVV-DWQGDTPRPQQSVSKLWVAIGVMDAVD +QGRLSLADPVTVTRADLTVHQPIRTLVGKTGTTVGDLLRGAMSRSDNTANDVLLWRIGGP +VAVNRMLKDKGVAGVRFGPGERQLQARYLDAPLDGASANGVTLGLSLLAQGRLLSDRSTA +SLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS +TRQPIPARMRLMGDVTRAVIA-- +>[subseq from] Beta-lactamase n=3 Tax=unclassified Citromicrobium TaxID=2630544 RepID=A0A0P6ZSV2_9SPHN +--SFERQVAALADGSQGRIGVYAVDLTTGAEV-GVLADQRFPMASTSKVAIAATFLAGVD +QGRWSLSSEFELPG-------------RGTYISAREHLNLMITRSCNDCTDALLNAVGGP +QAVNAWMRSAGILDFQLTRNIAALVRATEIDLRDSATPRAMGQLLAGIYQGRWLSPSSRQ +VLMNAMGDTVTGKRRMTSALPMSANLAHKTGTLSR-TASDIGIFYTPDGRPIAAAIYVTG +QSASMAVEN-------------- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9N7V9_9BACT +-qKLESSIREVDHNLDGVLGVAIEDLTTGQKF-FLHEDELFPQASSIKIAVLAELYHQAQ +SGKAKLSDLYTISSSDLVPDSDIMLGLTPSVITNRDLATMMVAVSDNSATNVLIDRV-GM +ENVNALMDSLGLTHTRLRRKMMDVKAA-GEGRENISTPREMMSLLEQIYRGKVLNKEMAA +DFLKMLSTHKQ--SFIPRDLPDGVRTANKPGELE-GVRNDSGIVFAQNR-PYVICVMTTY +LH-TEHDGEDAIARISSAAYRMf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Serratia fonticola TaxID=47917 RepID=U6A6K4_SERFO +--------------------------------------------------AVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDERDTSSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTTWVVGD-------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520J9Z6_SPHSX +----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWDAMTVMDLRD +QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYGIAVMIGD +TIRPMPERQKLIQAAAAAVANY- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. WG TaxID=1592629 RepID=UPI0002EAD03A +--ALLNAVQALGAEFDGQVAISVRDIDRGWMV-AWNGERAFPQQSVSKLWVAIAVFDAID +AKRLSLTTPVTVTRADLTVHQPIRALVGANGTTVGALLQCALTRSDNTCNDVLLWKVGGP +AAIRRMLADKGVRGVSFGPGERELQARYLADPYDGASANGITLGLSLLGQQKLLSPASTD +RLLSIMLASKTGPLRLKSGLRPGWKLAHKTGTGQATGYNDVGLLTAPNGHRYAVAVLIAS +TRRPIPVRMQLMGDVTRAIIR-- +>[subseq from] serine hydrolase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI0009E704EE +--DLLNAVQALGASFKGQVGITVRDIDEGWVV-AWDGDTRRPQQSVSKLWVAIAVMDAVD +RGQMALSDRVTLTRADLTLHQPIRALIGADGTTIEELLRGAMTRSDNTCNDVLLWRVGGP +AAINRMLDAKGVEGVTFGPGERVLQARYLAAPYDGASANGVTLGLSLLAQGKLLSARSTA +SLLTLMRSSKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDIGLLVAPNGHRYAVAVMIAS +TREPIPVRMRLMGDVTRAVVA-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf412 TaxID=1736370 RepID=UPI0009EAA8B5 +---LQYRVDQLLRQFPGKAGAAIVAVDEGWSV-SSGGTLSLPQQSVSKLWVAMTVLAQRD +AGRLRLDDPVVVTRDDLTLHQPIASLVRGDGTTVGALMTRALTQSDNTANDRLLTFVGGP +SAVRAFIAEKRLGAIRFGPGERLLQARYVDNPPDGAAPLAIADALARLARGELLSETSTR +LLLETMGASRTGRARLKAATPAGWELAHKTGTGQNAGFNDVGLVTAPDGRRYGIAVMIGD +TTAPMRTRQFLIQNVASAL---- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=2 Tax=Sphingomonas mucosissima TaxID=370959 RepID=A0A245ZGU8_9SPHN +--ALEASIGQLVREFSGVAGVAVRAVDDGWTV-EASGRRLLPQQSVSKLWVAMTILDQRD +SGRLRLDDEVSLTPADLTVHQPTAYLVKG-GTTVGDLLFRALTQSDNTANDRLLTLAGGP +SAVRSFIERKQLGDIRFGPGERLLQAAYIDNPPDGAAPLAIADALARLARGELLSETSTR +LLISTLESSKTGRARLKAGAAPGWTLAHKTGTGQNAGFNDVGLLTAPDGRRYSVAVMIGD +TQRPMRDRQQLIQAVAATVT--- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter flavus TaxID=192812 RepID=A0A5P6N7R3_9SPHN +---LERQIAQLADGSNGRIGVYAIDLATGREI-GVLADQRFPMASTSKVAIAATFLAGVD +AGRWSLTSEFRLPR-------------PGGAMPAHRHLSLMISKSCNDCTDALLNAVGGP +RAVNKWMQEAGIEGFQLSRDIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSDYSRR +VLLDAMEETTTGKRRMRSALPLSANLAHKTGTLAR-TASDIGIFHTPDGRAIAAAIYVTG +QSPSMA----------------- +>[subseq from] Uncharacterized protein n=2 Tax=Desertifilum sp. IPPAS B-1220 TaxID=1781255 RepID=A0A1E5QLV1_9CYAN +---LKNSLGAIAQQYNLSPGIFLIDLDTGAYV-DLNGTQTYAAASTIKLPILVAFFQDVD +AGKIRLEEMLVMKPEHIATGAGDLQYQPAGTYSALDVATKMMTISDNTATNMLIERLGGA +EALNQRFRSWGLKITALNNPLPDIEGT------NLTSPQELAQIMAIVNRGDWVQGRSRD +RILDIMGRTET-APLLKSGLGPGARLANKTGTLGV-LLADMGLVDTPTGKHYAIAVMVKR +EFGD-PTAEELIYQVSRAAYQHf +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas yabuuchiae TaxID=172044 RepID=A0A147ING4_9SPHN +------------------------------------------------------------ +-------------------------------RTAAKAMEAMIVRSDNLAADQMFATLGGP +AKVQQWVLSHNISGMRVDRTIAQLLRGHLADIKDVATPFAMVQLLRILDSGTALSSQSRA +YLLGLMRQCRTGTRRIRGLLPAGTLVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG +GR----DRQPVIAEVSRMIYDRf +>[subseq from] Serine hydrolase n=1 Tax=Leptolyngbya sp. 'hensonii' TaxID=1922337 RepID=A0A1Q8ZBE0_9CYAN +---LQDRIQTLRANYALKSGLFFLDVDTGNYL-DINGNKTFPTASIIKLPILIAFFQDVD +AGKIRLDETLVMRPELIASGSGTMQDLPAWSFSALKTATQMIVISDNTATNMIIHRMGGI +SVLNQRFRSWGLKKTVIRNWLPDLSGT------NTTTAREMVYLLSLLDQRKLLSPQSQD +EALGILRRTKT-RTLLPAGLGTGATIAHKTGDIGF-MLGDAGIIELPNGKRYLGAVLVIR +PYND-IAGRNFIRQVSGTVYSY- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter flavus TaxID=192812 RepID=A0A222EUF8_9SPHN +-rELDQAVSRIGGTFDGHVGIAVRDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD +AGRLDLSEMVAIRTADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA +EAVQDFLDTHGLASIRFGTDERSKQSGYLADPIDGAPPVALVEALTRLQCGELLSAGSTG +LLLGTLARTKSGPQRLKAGAPEDWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR +TREPTPVRMEMMQQVVRAVAR-- +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium Mal64 TaxID=2527991 RepID=A0A5C5ZJ80_9BACT +--DLEKILRPLLEGHRGVVTAAVKHLGTGESF-THEADRPMPTASLIKLPLMVAAYEAID +RGETALDHKITLREEDKVPGSGVLTPHIGAGITLADAIQLMIAFSDNTATNLVIDQV-GL +GATTELMEGLGLHNTKLNAKVFRRDTSINPEGSGSTTAAEILSLVEMLHARELVSPAASD +AMLERLFACQD-RGKLCRYLPEETRVAHKGGSVS-ASRCDAGLMETPAG-PIALAIFTTD +NEGDENEAELLAGEFGRVVYQHf +>[subseq from] Beta-lactamase class A n=1 Tax=Thermoanaerobacterium sp. RBIITD TaxID=1550240 RepID=A0A285BET8_9FIRM +----YENIQNLIKSTSGNVGASIKNLKTGETI-NINENLVFPSASTIKIVIMAEILRKVK +EGFIRLNDNIILSNFMKTGGSGILHELNSGHFTIEELITLMIIISDNTATNILIDIA-DM +KNVNNMAVSLGMSHTKLQRKMMDFEAA-RCGKENYTCAADMTHILELINDGKVINKEYSN +MMLDILKRQQD-LGRLDLYLPENTIIAHKPGELDF-LEHDVGIVYLKNCT-YIISVLTNK +MKT-NLEGRKTIGKISKMVYDEy +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas viridiflava TaxID=33069 RepID=UPI0013DFD2BA +------------------------------------------------------------ +--------------------------------------------SDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGVRGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. TaxID=1872480 RepID=A0A2E1Y9H1_9SPHN +---LGQRISQLAEGSQGRIGVYAIDLTTGHEI-GVLADQRFPMASTSKVAIAATYLAGVD +AGKWSLTSEWRLPR-------------PGGALSGKQHLDLMISKSCNACTDALLNAVGGP +KAVNDWMRSAGITEFQLTRDIATLVRASAVDFRDSATPRAMGQLLAGIYQGKWLSTSSRG +VLMNAMRATTTGKKRMRSALPTSAGLAHKTGTLAR-TASDIGIFHTPDGRAVAVAIYVTG +QSPSMAV---------------- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter flavus TaxID=192812 RepID=UPI00102E8DA9 +---TRQAVSRIGGTFDGHVGIAVRDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD +AGRLDLSEMVAIRTADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA +EAVQDFLDTHGLASIRFGIDERSKQSSYLADPIDGAPPVALVEALARLQRGELLSAGSTG +LLLGTLARTKSGPQRLKAGAPEDWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR +TREPTPVRMEMMQQVVRAVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Aphanothece sacrum FPU1 TaxID=1920663 RepID=A0A401IJY6_APHSA +--NLKTKLQAIAAKYKVKPQAWFLDLDNGAYI-NLGGSTPIPAASTIKIPVLVAFFEEVD +KGNIHLDQMLIMDKEVITTGSGDMQYQVGKKFTALEVATKMIIISDNTATDMLIRQIGGK +EVLNQRFKEWGLTHTVINNRLPDLEGT------NTTSSEDLGKLLAKVERGDFLSPRSRD +RLLAIMEKTKT-RTLLPQGIEKEANIAHKTGDIGT-ILGDAGIIDIPTGKRYIGVAFAQR +AYND-PAARSLIQEFSRTVYQHf +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. BPTF-M16 TaxID=2169535 RepID=A0A411ZBE0_9SPHN +---LAGQLYRIGEEFDGRVGLAVVDVGRERSM-HHNGNELMPQQSVSKLWVALTALDQAD +RGEFSIEDVTTIRRQDLTLYQPVRSIVLTRGTSYRDLIRRAIIQSDNTANDKVLNAIGGP +DAVRETIVQKGLGAIRFGPGERIMQSSYISDPIDGATPNAIAQALARLARGELLSAGSTR +AFLQWLTEVKSGPNRLKGGIAPGWTIGHKTGTGQQAGYNDVGILTAPNGDQYAVAVLVAR +TAIPLRERMAMMHEVVGAVIDY- +>[subseq from] serine hydrolase n=1 Tax=Aphanizomenonaceae TaxID=1892259 RepID=UPI000C1C6063 +----KTTIENLSAANNLIPGVFIVDIDSGAYV-DVSGNNNFPAASTIKIPVLVAFLEDVD +RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIEVATKMMTISDNTATNMLISKLGGK +ELLNSRFRSWGLVNTAIQSPLPDLEGT------NTTSPKELASLIAKVNQGELISMRSRD +LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR +PH-NEPAAAKLINSISQATYSY- +>[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI000F63681D +--TASDALAALELRNGGRLGVFALDAGSGRSL-GWREDERFGMCSTFKLLLAATVLDAAR +QGRLDGTAPIHFSDDDLVPHSPVLREHLALGLTAPELARATQLTSDNAAANLLIRKLGGP +EAVTALWRASGDEVSRLDRLEPDMNLLPPGDLRDSTSPRAMAQHVARLFTSEMLVPEDRE +RLREWMVETGTGLARL-------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. AP23 TaxID=499656 RepID=A0A109LUE6_9SPHN +---LERQLAQLADSSNGRIGVYAIDLSTGREI-GVLADQRFPMASTSKVAIAAVFLAGVD +EGRWSLTSEFRLPR-------------PGRVLPAYKHLSLMISKSCNDCTDALLQAVGGP +RAVNKWMRDAGIEGFQLTRDIATLIRAWSVDAKDSATPRAMGQLLAGIYQGKWLSDYSRR +VLLDAMEETTTGKRRMRSALPASANLAHKTGTLSR-TASDIGIFHTPDGRAIAAAIYVTG +QSPSMA----------------- +>[subseq from] serine hydrolase n=1 Tax=Spirulina major TaxID=270636 RepID=UPI000A075430 +---LQTQIDAAIAGYAGHVGLLVVDLDTGDYV-NSNGLESFSAASTIKLPILVAFYQDVD +QGAVSLDESLTMTAELVAAEAGTMKYPVGTQFSALETVTTMITISDNTATNMIIARLGGY +DALNQRFQDWGLQQTEVKQWLPDLGGT------NVMSPVDVVNLLIRLERGELVSLRSRD +RILSTLTAVKN-RQLLPQGLDEKAVIAHKTGTLG-GVLADVGLVDVPNGKRYAIAVITKR +PRHD-PQAQTLIQTLSRLTYQHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf38 TaxID=1736217 RepID=A0A0Q4LFB3_9SPHN +--DLLNAVQALGARFDGQVGISVRDIDENWGV-DWQGDTPRPQQSVSKLWVAIGVMDAVD +RERLSLGDPVTVTRADLTVHQPIRTLVGKTGTTVGDLLRGAMTRSDNTANDVLLWRIGGP +AAVNRMLRDKSVTGVRFGPGERQLQARYLDAPLDGASANGVTLGLSLLAQGRLLSDRSTA +PLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS +TRQPVPVRMRLMGDVTRAVIA-- +>[subseq from] Penicillin-binding protein, transpeptidase n=2 Tax=Aphanizomenonaceae TaxID=1892259 RepID=D4TRV4_9CYAN +----KTTIENLSAANNLIPGVFIVDIDSGAYV-DVSGNNNFPAASTIKIPVLVAFLEDVD +RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIEVATKMMTISDNTATNMLISKLGGK +ELLNSRFRSWGLVNTAIQSPLPDLEGT------NTTSPKELASLIAKVNQGELISMRSRD +LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR +PH-NEPAAAKLINSISQATYSY- +>[subseq from] serine hydrolase n=1 Tax=Cylindrospermopsis raciborskii TaxID=77022 RepID=UPI000778B4C2 +----KTTIENLSAANNLIPGVFIVDIDSGAYV-DVSGNNNFPAASTIKIPVLVAFLEDVD +RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIEVATKMMTISDNTATNMLISKLGGK +ELLNSRFRSWGLVNTAIQSPLPDLEGT------NTTSPKELASLIAKVNQGELISMRSRD +LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR +PH-NEPAAAKLINSISQATYSY- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00098EA058 +------------------------------------------------------------ +------------NKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNTVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5205 TaxID=2019671 RepID=A0A2N6LUS0_9CYAN +--QLNTQVKALMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD +AGRIQLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS +KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] serine hydrolase n=1 Tax=Cylindrospermopsis raciborskii TaxID=77022 RepID=UPI000C1BE692 +----KTTIENLSAANNLIPGVFIVDIDSGAYV-DVSGNNNFPAASTIKIPVLVAFLEDVD +RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIEVATKMMTISDNTATNMLISKLGGK +ELLNSRFRSWGLVNTAIQSPLPDLEGT------NTTSPKELASLIAKVNQGELISMRSRD +LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR +PH-NEPAAAKLINSISQATYSY- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. HDW15B TaxID=2714943 RepID=UPI001407DDFE +------------------------------------------------------------ +--------------------------------SARSLMASMIIKSNNAATDILLNDLGGP +DTLQDWIEQHRLSGMRVDRTIARLLAAKRDDLRDSSTPMAMLNMLSKLDKGELLRPANKQ +YLLGLMAKCTTGKNRMRALLPAGTRVEHKTGTLN-GLTADVGFITLPDGRRIAVAFFARN +GS----DRPRTIAEAAWTVYYGf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Cra20 TaxID=1327635 RepID=A0A2K8MLD2_9SPHN +-----TSIDNITRNFNGLVGVAVTSIDDGWTAsNVTASRPMPQQSVSKLWVAMAVLDAVD +RGTVRLDDPLTITRSDFTLHQPIAALVKGDATTVGEIMRRAMQLSDNTCNDKLLRLVGGP +QAVRDFIYRKQLGTIRFGPGERLLQAAYVKDPPDGAAAASIADALARLHRGELLSASSTN +WLLATMGGAKTGKARVRGAVPPGWLYGHKTGTGQTAGFNDVGILTAPDGRSYAVAVMIGD +TSRPIRERQLLMQAVGSAIVAH- +>[subseq from] Serine hydrolase n=1 Tax=Proteobacteria bacterium SG_bin6 TaxID=1827383 RepID=A0A1W9HKW6_9PROT +---LQNSVQLLVRQFQGKVGAAVASVDQGWLL-SANGDVRLPQQSVSKLWVAMTVLDGID +AGRFTLDTPMKVTREDLTLHQPIAAMKPGQGTTVGDLLQRALTQSDNTANDRLLRFVGGP +EAVRGFIARKALGNIRFGPGERLLQAAYVADPPDGAAPAAIATALSRLKQGELLRPFTTG +YLIATMESSKTGRMRLRGAVPLGWSFGHKTGTGQTAGYNDVGILTAPDGRSYTLAVMIGD +TRRPIAERQALMQQVVASIIAY- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. HI00D59 TaxID=1822215 RepID=UPI0012E8735A +-rELDQAVSRIGGTFDGHVGIAVRDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD +AGRLDLSEMVAIRSADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA +EAVQDFLDTHGLASIRFGTDERSKQSGYLADPIDGAPPVALVEALARLQRGELLSAGSTG +LLLGTLARTKSGPQRLKAGAPENWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR +TREPTPVRMEKMQQVVRAVAR-- +>[subseq from] Uncharacterized protein n=1 Tax=Chondrocystis sp. NIES-4102 TaxID=2005460 RepID=A0A1Z4RVV9_9CHRO +----KLKLQELGQQYSLKPEVFIADLDTKGFV-NLEASNAIASASTIKLPILVAFFQDVD +AGKISLSEKLTITKEDVATGSGDLQHKPGTKLSALETAEKMMVISDNTATNMLIKRLGGQ +ESLNQRFTKLGLTATKIRNPLPDLDGT------NTTTPEDLGNLLINISNGELVSLRSRD +RLLGIMRNIVR-DTLLPQGLEPGAIIAHKTGDIAS-VLGDVGMIDMPNGKRYIAAILVKR +PTNS-FEAQEFIQKASRLTYQHf +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus centrosporus TaxID=54910 RepID=UPI000F09BDF6 +---WQQVIQETLIDAPGVFGVAATHLETGETA-GNLENELFQLASAFKIPILVTLMRDVE +AGKITLDQRVTLKWEERVPGSGILQELDAGALTVKDLATLMTIVSDNFATDLILQLV-GL +DNVNAHMRELGFSQIHLRHNCWQLLNSQGTLENNVATPAELNRLLVMIGKKEILTPASCD +LMLDILRRQHY-NSRLPYLLPPGTKVAHKTGTVNE-VVNDAGIIYLPDNKGAIAVTVLSR +GIKDKQAAELTIAKVAKAVYD-- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingobium abikonense TaxID=86193 RepID=UPI00078840FE +-----SVIRNLGQSFKGKVGIAVRRVGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD +RGKLRLTDTTTLTRNDLTLHQPSAALVAKQGTSYSDLMRRAMTQSDNTCNDALLRAAGGP +DAVRGFLARRMIKDIRFGPGERLLQSNYLSNPPDGAAPGSIVAALAKLKQGDMLSPASTR +LLLNIMSEAKTGPQRVKGGVPAGWHYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTVPIPERWALMQAVSKAVAA-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1JDM0_9ZZZZ +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIKG------------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A353BXE9_9FIRM +---------QAIDFQKLNCAFVVKNLQTGECA-SYNSEARVASASLIKLAVMAESIRQVK +EGKLNLKQRLVVREEDKVDFSILTLLATGNSYTLRDLLTLTIVQSDNTAANILIDLT-GM +TEINKFCNDLGLKDTVLRRKMMDGEA-RKAGRENYTTAADMARFLELLYQGKLLDPESCS +LMIEIMKKQLD-NTMIRLYIPDDTVVAHKTGELE-GISHEAGIVYHDKA-DFIIVMLVWD +AL-SGNDARQTIGRAAKTVYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFOXYA2_FULL_53_38 TaxID=1797961 RepID=A0A1F9XR82_9BACT +--TMVTALENIAYNYNGHVGIYIKDLNSDKVW-EYNPDRLFPSASLIKVPIMIAICEKIK +RGELSLDTQIKLTRRDRAGGSGSLKWVREGTLSVTEIIYKMITESDNTATKMLVEYG-GI +NYFQQAFENLGLVYTKIYPEGLSLTSS-RVVRENYTTAREMAGLMERIYKGEMVDRSLSE +FMLDVLKHNKS-RSRLRKGLPIGWEIGHKTGLLRR-SCHDVGIVFSPRGD-YLIAVLTSD +VP-DYTSAKGFISRVAKLTYEYy +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas phyllosphaerae TaxID=257003 RepID=UPI000684E963 +--ALQQRVTQLIRSFPGKAGAAIQAVDEDWIV-SEGGALYLPQQSVSKLWVAMTVLGQRD +AGRLKLDDPVLVTRDDLTLHQPIAGLVTGEGTTVTGLLTRALTQSDNTANDRLLTYVGGP +AAVRRFLAEKHISGIRFGPGERLLQSRYIDNPPDGAQPAAIVEALARLARGELLSETSTR +VLLDTMANSHTGRARLKAATPAGWTLAHKTGTGQNAGFNDIGILTAPDGRRYAIAVQIGD +TTAPMRVRQVLIQQVAAAL---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V594_9BACT +------------------------------------------------VMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSLRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASILTGLPASWVV---------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0009906A7A +------------------------------------------------------------ +------------NKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Serine hydrolase n=1 Tax=Oscillatoriales cyanobacterium CG2_30_44_21 TaxID=1805292 RepID=A0A1J5H0R9_9CYAN +-----AKIKELAAQKDLAMQMMAIDLDSGTYV-QVGANQKIAAASTIKMPLLVAFFQDVD +AGKIKLDEMLEISEDVVVGEAGFQGLALGTKKTALETATQMIVISDNTATNMIIKRLGGV +ATVNQRFKSWGLKNIVANNKLPDLEGT------NTISTQDMVTLLAMVDQGKLVTPRSRD +RFMDIMSRPIT-NTLLPQGIGAEARIVHKTGDIGS-AVGDAGIVDMPNGKRYAIAVMVTR +PNND-QRANELIRQISRASYDYf +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. HI00D59 TaxID=1822215 RepID=A0A165SA22_9SPHN +-rELDQAVSRIGGTFDGHVGIAVRDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD +AGRLDLSEMVAIRSADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA +EAVQDFLDTHGLASIRFGTDERSKQSGYLADPIDGAPPVALVEALARLQRGELLSAGSTG +LLLGTLARTKSGPQRLKAGAPENWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR +TREPTPVRMEKMQQVVRAVAR-- +>[subseq from] serine hydrolase n=1 Tax=Chondrocystis sp. NIES-4102 TaxID=2005460 RepID=UPI000BBCB999 +----KLKLQELGQQYSLKPEVFIADLDTKGFV-NLEASNAIASASTIKLPILVAFFQDVD +AGKISLSEKLTITKEDVATGSGDLQHKPGTKLSALETAEKMMVISDNTATNMLIKRLGGQ +ESLNQRFTKLGLTATKIRNPLPDLDGT------NTTTPEDLGNLLINISNGELVSLRSRD +RLLGIMRNIVR-DTLLPQGLEPGAIIAHKTGDIAS-VLGDVGMIDMPNGKRYIAAILVKR +PTNS-FEAQEFIQKASRLTYQHf +>[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter thiooxydans TaxID=416169 RepID=A0A154QFZ0_9GAMM +-----------------------LDLRSGEAW-RVNARQAFPMMSVFKAPVAGAVLDRIE +HGGLSMELTVVIRRRELSSGT-IRDHFEGERFTVRQLLADAVSRSDNTAVDALLDTIGGP +RVVTAFLRSRGIDGMRVDLGERDFQSAYLVDPRNRSTPDAAAQFLRKLWEGQLLPPEPTR +HLLDLMYAQTT-PSRLRLGLPPGARLADKCGTSYTAAYNDIGILSWPDGHAIVVAAFLTA +SVDPKGERDALFADLARTVAA-- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000FA20573 +------------------------------------------------------------ +-------------------------------------CSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNR------------- +>[subseq from] serine hydrolase n=1 Tax=Geminocystis sp. NIES-3709 TaxID=1617448 RepID=UPI0011875654 +--DLKNKFIQLKTKYNLEPGAFFVDLDNGSFV-NFNGTTTFSAASTIKIPILVAFFQDVD +AGKIYLDEQLATSAKNIGSGSGGMQYQPGTKYTAIHTATEMIINSDNTATNMIIERLGGK +DELNKRFKEWGLDVTLINNSLPDLEGT------NTTSPKDLAITLAKVNQGELISLRSRD +RLLDIMRQTRT-RTLLPQGIEKDATIAHKTGDIGT-ILGDAGIVDIPTGKRYIGGVLVKR +PYND-YSARTLIQEISRTAYQHf +>[subseq from] Beta-lactamase class A n=1 Tax=Geosporobacter subterraneus DSM 17957 TaxID=1121919 RepID=A0A1M6H6Q8_9CLOT +----EKGIRMLLGNTMAKTCVVLKDLRKDEWIfRKDETMVVPSASTIKILIMVEALKQVQ +EGKYQLDERFSIMEEDKVDYSIL-SDLTTDSYTFRDLIMLMIIVSDNTATNVLIDLL-GF +DAVNHRAMEIGLQNTRLQRKMMDFEAA-KAGKQNLTTAMDMALLMEKIYKKEVLNLDLCN +LALDILKRQKD-KTMLKRYIPEDVEIAHKTGDLTN-LNHDIGIIFLPQST-YLLGVFVSE +AK-SNLEAQQTIGEISKTVYDYy +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Ant20 TaxID=104605 RepID=A0A0A6CXG7_9SPHN +-----NAVQALGASFKGQVGITVRDIDEGWVV-AWDGDTRRPQQSVSKLWVAIAVMDAVD +RGQISLSDRVTLTRADLTLHQPIRTLIGPDGTTIDELLRGAMTRSDNTCNDVLLWRVGGP +AAINRMLDAKGVEGVTFGPGERVLQARYLAAPYDGASANGVTLGLSLLAQGKLLSARSTA +SLLTLMRSSKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDIGLLVAPNGHRYAVAVMIAS +TREPIPVRMRLMGDVTRAVVA-- +>[subseq from] Uncharacterized protein n=2 Tax=Tuwongella immobilis TaxID=692036 RepID=A0A6C2YMI9_9BACT +--ALAEKLKPLIAAHQGTVAIGVQHLGTGATV-WHNADEVMPTASLIKLPIMVEVYHQVA +EKKLSLDDRIQLTKEDMVPGSGILTANFSEGFPLRDAVTLMIVFSDNTATNLVLDKI-GI +PSTNFRMAKYGMPNTRVNAKVFRGSKRTKQYGLGSTTAREMITLLHLLHQKKLVSAAACD +AMLATLRRCDD-DEKFPRFLPASVKVAHKTGSVSD-ARTDAGILEFPQG-PVAICVLTAK +NRKADNAGNRLCADVAKVVYQHy +>[subseq from] serine hydrolase n=1 Tax=Allonocardiopsis opalescens TaxID=1144618 RepID=UPI000D049318 +-------LVALEERTGRTVGAVLLE--GGRRLvAHRPDQVMPTCSVFKSFLVAALLHDRD +DREYWYDAAIDYDESDVVINSAVLSERSG-PISPHDLAEAALRYSDNTAANLLLAELGGP +AVLTEFTRSLGAAVTRFDRLEPELNAAVPGDDRDTSTPAEVAMLMHAVLVERSAGAYTAA +RLNTWMLWNET--SRITEALRTGDELTDRTGAGAYGVVNDAGVLYRPGQPPRSFAVMTRT +DDEDAENDDAVVLEAARLL---- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A350D3C0_9BACT +--KLISDLRSFSDQLDGVLGLAIKDLSTGRTI-FINENEIFPQASSIKMTILLEVLKQAE +EGKLKLDEFINLTPEAKVGGGLILAYYPALKISIRDLCVLMVVLSDNTATNLLIDRA-GL +KNINNRLQGLGLNQTKLQRKMMDVKAA-GEGRENLSTPLEMMSLLEKIYKGSVLSPASKQ +EFFNILSLPKD--SPLQQAVPEGVVVADKPGELE-AVRCNSGLVFLKKH-PYVICVMTTY +LK-NEAEGNATIKKIGQAAFSYf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9LUK5_9BACT +haKLEAGLLREAEGLDGVMGYFIQDLATGETF-EHNAELVFPTASTIKLTVLLELMRQDQ +EGKLSLDEKHTVRRNETAAGDPILYMLGDGTMTLADLATFMVVLSDNSATNILIERV-GM +ANVNSRAGSLGLNQTHLRRKMMDLEAA-RQGNENVSTPRELSGLLAKLRAGKALDPAHTK +KYLALLALPK--DSLFNKALPSGTVIEDKPGALE-GVRCDAGIIEIPGR-PFVITVMTTY +LG-DENQGERAIESVARKAYEHf +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI00117CA2AF +-----HMIRQLLQETPYNVHMIVKDLRTDETFiCERPDAVFSSASLIKVPILLAVLHHVQ +SNQGSLHQVLTITPEDWVDFSGISEQQLVS-TTIYELLVWMIITSDNTATNVLINYI-GM +DALNRYFREIGLTHTILQRKMMDFER-LANGVDNVTTTRDMAHIFTHIYRQDLLMPSFSA +LAIDILSRQRV-HDLLRRYLVDDVRIAHKTGGLD-AVDHDVGIVYGDSKD-YLIGVFVTE +VTNN-QDARQLIGRISKVVYEY- +>[subseq from] Serine hydrolase n=1 Tax=Chryseobacterium nematophagum TaxID=2305228 RepID=A0A3M7TLR1_9FLAO +--QLQEKIKHIIYTAGGKIGVGVKGMDFKTGF-VINGNHEYPMMSVFKFPIAFAVLDKVD +KGELKLNQKFHMPKESLDTYSPMIKDFPNQDVTLADLLMYMVTKSDNNACDFLITKVGGP +AAINKYLHRAGVKDIAIAYTEGAMEKEKSLQYKNWLKPGGSLQLLQLLFDQKLLSKSNND +FLFQIMRELPDGSKRITVQLPAETELFHKTGYSGMAAFNDMGIVTLPNGKHLAISVFLSD +FQGPLDRGINVIAAISKEIWDFy +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. CHR27 TaxID=2506423 RepID=A0A4Q1KEZ1_9SPHN +--ALRVQIETLGSSFNGTVAISVRPVDADWEA-AYNADSLMPQQSVSKLWVAMAALDAVD +RGKLTLLDPVTVRPDDLTLHQPLAAMVRSTGTDVADLMTRAMTESDNTANDVVLRQIGGP +EAIRGYLARRFLANIRFGPGERVLQSDYLANPMDGAAASSITLALARLKRGEMLSPASTA +YLLAVMHEAKTGRQRIKGGVPAGWSYAHKTGTGQATGFNDVGIMTAPDGTSYAVAVMIAS +TTVSIPERWAVMQGVARAVAAY- +>[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. HN-E23 TaxID=2488860 RepID=A0A3N5DT47_9SPHN +--DLAQTIDSLGEDFGGLLGIAVEDVDAGWTT-AYNGERMLPQQSVSKFWVSLTALDQAD +RGELDLDRTIVLTRKDLTLHQPIRAEILLRGTTPRELMEQALTHSDNTANNAILEAVGGP +AAVSTMMARHDITGVRFGTDEITKQSAYLDDPIDGATPLGMVHALSRLARGELLSERSTR +LMIETLKRTHSGPRRLRGGREGDWVVAHKTGTGQQSGYNDVGLVISPGGRTYAVAVLIGW +TRRPTIERMAMMQKVTRAVI--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudanabaena sp. PCC 7367 TaxID=82654 RepID=K9SF80_9CYAN +--ELKAQINQLTAAEDLGLQALLVNIDTESYV-NINADVPIAAASTIKLPLLVAFLQDVD +AGKIRLDEQLEISEDVRVGHAGELQYEPGTTVSALETITLMITISDNTATNMVIKRLGGA +GAVNERFASWGLNATVIRNPLPDLEGT------NTTSPQDLVNLLAMVDQGKLIAPRSRD +RFMDITRRTLT-DTLLPQGIGPEARIAHKTGDIAS-VVGDAGIIDMPNGRRYIMAALVQR +PDND-QRANDLIRQVSDATYQHf +>[subseq from] serine hydrolase n=1 Tax=Citreicella sp. 357 TaxID=766499 RepID=UPI0009FF7783 +------------------------------------------------------------ +-------------------------------------CSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNPL------------ +>[subseq from] Serine hydrolase n=1 Tax=Anabaena sp. MDT14b TaxID=1710886 RepID=A0A1B7W8E0_9NOST +-----NSLQTLTANSDLIPGVFLLDLDNGGYI-DINSNISFAAASTIKIPILIAFFQDVD +GGKIRLDEMLILQKEMIVGGSGNMQYQPTGSYTALDVATKMITISDNTATNMLVAKLGGQ +EALNGRFRSWGLITTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNMVSMRSRD +LILNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR +PNND-PRAAKLISSISSTAYQHf +>[subseq from] Beta-lactamase n=1 Tax=Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437) TaxID=111780 RepID=K9XQQ8_STAC7 +--SLKSKLQTLASQYKLQPAIFLVDLDDHSYV-SIQGSGAIAAASTIKIPILVAFFQDVD +QGKFRLDQELTMNKEDIGSGSGSMQEKPGTQFTTLEVATKMITISDNTATNMLIKIMGGA +EKLNQRFLEWGLTETVIRNPLPDLEGT------NSTTPEDLGNLLINLERGKLVSLKSRD +RMFTIMSNLVR-NTLLPVGLEADATIAHKTGDIRS-VLGDVGIIDMPNGKRYVASVLVKR +PDND-PQAKEFIQKMSQVAYQH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A649UI99_PSEAI +---------------------FAIDTGSGNTF-GYRSDERFPLCSSFKGFLAAAVLERVQ +QKKLDINQKVKYESRDLEYHSPITTKYKGSGMTLGDMASAALQYSDNGATNIIMERLGGP +EGMTKFMRSIGDNEFRLDRWELELNTAIPGDKRDTSTPKAVANSLNKLAFGNVLNAKVKA +IYQNWLKGNTTG------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Riemerella anatipestifer TaxID=34085 RepID=J9QX37_RIEAN +-nNLKYQIEKIISSKKGDFGISIID-ENNNII-EINGNKSYPLLSTFKFPIALTILHKVE +NGELLMQQQIFIKKEELLEWSPFKEKYPNGNISLEEALHWMIVYSDNNMTDILLRLIGGT +NAVEKFI---DDENFVIKNNEDEMHKDWNSQFINKSTPNSFTKLLKNFSEGKMLNSENTK +WLYESMVNSKTGVKRLKGKLP-NVKIAQRAGTSFTGAINNVGIMQLPNNQKIYITVFIHN +TSEEFNKGEEIIADIAKTTYEFy +>[subseq from] serine hydrolase n=1 Tax=Cronobacter dublinensis TaxID=413497 RepID=UPI00131A1E2E +------------------------------------------------------------ +---------------------------------------------DNTAANLLLTTIGGP +KELTAFLHSMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. BK235 TaxID=2512131 RepID=A0A4R2PJU1_9SPHN +--ALQARIEQLVRNFPGKAGAAIVAVDEDWVV-QQGGDLSLPQQSVSKTWVAMTVLSQRD +EGRLTLDDPVLVTRDDLTLHQPIAGLVGANGTTVGGLLTRALTQSDNTANDRLLTVVGGP +SAVRRFIAKHQLGAIKFGPGERLLQSRYIDNPPDGAAPVAIAGALARLARGELLSETSTR +ILLDTMAASRTGHARLRAATPPGWKVAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD +TAAPMRLRQQLIQNVCAAL---- +>[subseq from] Beta-lactamase class A n=1 Tax=Paraburkholderia fungorum TaxID=134537 RepID=A0A1H1JV03_9BURK +-----AELQRIIEYSRGSVGVSALHVETGERL-GLHEDCRFPLESTIKIAIAMKVLALVD +AGELALSDWIEVQSSEMNSGGPLGEEFLHDGLSVMNLLEPMITRSCNTSTDVMFRVAGGA +EAVADYVETLGIEGFESRYTMRHALCDYRNDLRDQCTPYTMIELLNALWSGKGITRASRD +LLLDIMSRTTTSPERVKGRLPQGVPFANKTGSGL-GAAADVGFLTLPDGGTVALAVYVKD +SPENMAYRNSIIADVARLAYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Poribacteria bacterium TaxID=2026781 RepID=A0A495Z2Y4_9BACT +-----SAIQDFTAHTEGIIGVAAKHLETDKRV-SHNADTIFFTASTLKVPLLVELYRQVD +AGIIDVHQRIDLTDALRVPGSGVLKELAAGLPTIHDLAMLMIIISDNTATDILYNQV-GG +DNINNTMQQLGLTHTHIPMTCRELLYGFSEDRSDVSSPNDMCCLLELIYDGDILSPQSRG +AVLDILKRQQL-STVIPHALPSGTVVAHKTGSYHS-VRCDVGIVFSPTG-PYTVAIMAKQ +MTGDRLSVDASLAAVSRAVYDEf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. WG TaxID=1592629 RepID=A0A0W1QLM6_9SPHN +-----NAVQALGAEFDGQVAISVRDIDRGWMV-AWNGERAFPQQSVSKLWVAIAVFDAID +AKRLSLTTPVTVTRADLTVHQPIRALVGANGTTVGALLQCALTRSDNTCNDVLLWKVGGP +AAIRRMLADKGVRGVSFGPGERELQARYLADPYDGASANGITLGLSLLGQQKLLSPASTD +RLLSIMLASKTGPLRLKSGLRPGWKLAHKTGTGQATGYNDVGLLTAPNGHRYAVAVLIAS +TRRPIPVRMQLMGDVTRAIIR-- +>[subseq from] Serine hydrolase n=2 Tax=Hapalosiphonaceae TaxID=1892263 RepID=A0A4D9CLG3_MASLA +--QLNTQIKALMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFQEVD +AGRVKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +ARLNQRFQSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLSALLSNNQLLNDGSRS +QALDIMRRVKN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] Serine hydrolase n=1 Tax=Hapalosiphonaceae cyanobacterium JJU2 TaxID=2109628 RepID=A0A328ICR5_9CYAN +--QLNTQIKALMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFQEVD +AGRVKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +ARLNQRFQSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLSALLSNNQLLNDGSRS +QALDIMRRVKN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf226 TaxID=1735691 RepID=A0A0Q4HYU5_9SPHN +-----NAVQALGASFKGQVGITVRDIDEGWVV-AWDGDTRRPQQSVSKLWVAIAVMDAVD +RGQMALSDRVTLTRADLTLHQPIRALIGADGTTIEELLRGAMTRSDNTCNDVLLWRVGGP +AAINRMLDAKGVEGVTFGPGERVLQARYLAAPYDGASANGVTLGLSLLAQGKLLSARSTA +SLLTLMRSSKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDIGLLVAPNGHRYAVAVMIAS +TREPIPVRMRLMGDVTRAVVA-- +>[subseq from] Beta-lactamase n=1 Tax=Geminocystis sp. NIES-3709 TaxID=1617448 RepID=A0A0D6ARF5_9CHRO +--DLKNKFIQLKTKYNLEPGAFFVDLDNGSFV-NFNGTTTFSAASTIKIPILVAFFQDVD +AGKIYLDEQLATSAKNIGSGSGGMQYQPGTKYTAIHTATEMIINSDNTATNMIIERLGGK +DELNKRFKEWGLDVTLINNSLPDLEGT------NTTSPKDLAITLAKVNQGELISLRSRD +RLLDIMRQTRT-RTLLPQGIEKDATIAHKTGDIGT-ILGDAGIVDIPTGKRYIGGVLVKR +PYND-YSARTLIQEISRTAYQHf +>[subseq from] Serine hydrolase n=2 Tax=Sphingomonas sp. Leaf343 TaxID=1736345 RepID=A0A0Q5Q225_9SPHN +--ALQAAVDSLIRGFDGRAGAAVRAVDDGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD +QGRARLDEPIAVLPADLTLHQPIAYLVAKTGTTVGGLLTRALTQSDNTANDRLLTFVGGS +SAVRAMIAKKRLGDIRFGPGERMLQARYIGDPPDGAAPLAIADALARLARGEILSETSTR +IMLDTMGASVTGRARLRAAIPPGWKISHKTGTGQNAGFNDVGLLTAPDGRRYALAVMIGD +TVRPIRERQQLIQAVAAAVT--- +>[subseq from] Uncharacterized protein n=3 Tax=Alistipes TaxID=239759 RepID=A0A4Y1WLN5_9BACT +------------------------------------------MMSVFKFPVALAVLDRMQ +REGIPLTQPISITPDLLLPYSPMRDSLPAGGLTLGQLLRYTVSESDNIACDILLREAGGP +EAVEAYVRSLGIGGIRIAASEEEMHRGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA +LLQRLLCGTTTGANKLKAGLPAGIVIGHKTGSSDRTADNDAGYVLLPDGRRYCIAVFVTE +SEENDAANAAIAASASRAAYEYf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf10 TaxID=1735676 RepID=UPI0012E31BCE +-----NAVQALGAGFEGQVGISVRDIDENWVV-DWQGDTPRPQQSVSKLWVAIGVMDAVD +RGRLSLADPVTVTRADLTLHQPIRTLVGKTGTTVGDLLRGAMSRSDNTANDVLLWRIGGP +AAVNRMLKDKGVAGVRFGPGERQLQARYLDAPLDGASANGLTLGLSLLAQGRLLSDRSTA +SLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS +TRLPIPARMRLMGDVTRAVIA-- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus simulans TaxID=1286 RepID=UPI000FEE94AD +-------------------GYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQYDLVEYSPVTENHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMP---------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium MED-G03 TaxID=1986231 RepID=A0A2A5YN62_9SPHN +-----SVIRNLGQSFRGKVGIAVRRVGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD +RGKLRLTDTTTITRNDLTLHQPSAALVARDGTSYSDLMRRAMTQSDNTCNDALLRAAGGP +DAVRGFLARRMIKDIRFGPGERLLQSNYLANPPDGAAPSSIVAALAKLKQGDMLSPASTR +LLLNVMSEAKTGPQRVKGGVPAGWHYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTVPIPERWALMQGVAKAVAA-- +>[subseq from] Penicillin-binding protein n=1 Tax=Fischerella sp. NIES-3754 TaxID=1752063 RepID=A0A0S3TL43_9CYAN +--QLNTQVKALMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD +AGRIKLNETLVMRRDLMTGGSGTLQKHPGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRY +KTLDIMRRVEN-RSLLPAGLGKGAMIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] Serine hydrolase n=1 Tax=Fischerella major NIES-592 TaxID=210994 RepID=A0A1U7H200_9CYAN +--QLNTQVKALMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD +AGRIKLNETLVMRRDLMTGGSGTLQKHPGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRY +KTLDIMRRVEN-RSLLPAGLGKGAMIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A525KXQ4_9CAUL +--ELQATIAKLAETYREPVGIAVTDVSDRWTA-QVAGSEVFPQQSVSKLWVALTVFQAVD +RHAMTLDQPVVLTPDDRSVYQPLASRIRGPNTTVYDLLRRQLTESDNAANDKLIREVGGG +GAVDRTLAEKGLAGLGVGETERDLQTQYLANPPDGAKPMAITESLAALKRGELLSPGSTE +AMLGLMGEAKTGLSRLRAGLPAGWSIAHKTGTGPSVGINDVGLVTAPDGRSFAVAVMMRE +TRKSVPARLVLFQRISRAIVDYw +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas yabuuchiae TaxID=172044 RepID=UPI0009FECD00 +-----NAVQALGAGFEGQVGISVRDIDENWVV-DWQGDTPRPQQSVSKLWVAIGVMDAVD +QGRLSLADPVTVTRADLTVHQPIRTLVGKTGTTVGDLLRGAMSRSDNTANDVLLWRIGGP +VAVNRMLKDKGVAGVRFGPGERQLQARYLDAPLDGASANGVTLGLSLLAQGRLLSDRSTA +SLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS +TRQPIPARMRLMGDVTRAVIA-- +>[subseq from] serine hydrolase n=1 Tax=Fischerella sp. PCC 9431 TaxID=1173023 RepID=UPI0003F92417 +--QLNTQIKALMARYKLQPGMFFLDLDTGNYL-DLNGEKVFPAASTIKFPILVALFQEVD +AGRVKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +ARLNQRFQSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLSNNQLLNDGSRS +QALDIMRRVKN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] Beta-lactamase n=1 Tax=Hapalosiphon sp. MRB220 TaxID=1704290 RepID=A0A0M0SDU6_9CYAN +--QLNTQIKALMARYKLQPGMFFLDLDTGNYL-DLNGEKVFPAASTIKFPILVALFQEVD +AGRVKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +ARLNQRFQSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLSNNQLLNDGSRS +QALDIMRRVKN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] hypothetical protein n=1 Tax=Planktothrix serta TaxID=1678310 RepID=UPI0009F932DC +---LKTAILGLAKDSKLKPGVFLVDLDTGNYV-DIQGELPLPAASTIKVPILVSFFQAVD +EGRLRLDEVLTMEEKHIAKGSGELQKPVGSKFTALETATLMITNSDNTATNMIIDRLGGI +ESLNQQFAFWQLKQTQMQNILPDLEGT------NKTSAKDLVTLMAEINQGKLVSVKSRD +FMLRIMQQTRN-RSLLPRGLGEGTFIAHKTGNIDS-VCGDIGLIDMLNGKRYLVGILVER +EA-DDPQANELIRQVSSTIYQYf +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. Ji-3-8 TaxID=2708539 RepID=UPI0013EA4BA7 +--KLTADFQPIANRVPGNLGVAVEDLGTGQII-SFNGEKRFPMQGVFKAPLGAAVMAEIE +AKRLKLDDTVLIEDVDLSPPSAIADAWPGRNYTIQELLERAVGQGDNTAADVLMKRVGGP +GAVTAWLQGRKVMHLDVDRYERQIQPAYLADPRDTATPLGALRFLEALNQAELLEPESRR +VLGRITGQTTLAPNRLRAALPDGARLAHVPGTARTDAVNDIGVYTLKDGRKFAVVAFVSG +SALSVADQEKAIADVGRVVIK-- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus nitrificans TaxID=651560 RepID=A0A3M8CUA5_9BACL +---WQQVIQETLIDAPGVFGLAVTHLETGETA-GNLENELFQLASAFKIPILVTLMRDVE +AGKITLDQRVTLKWEERVPGSGILQELDAGALTVKDLATLMTIVSDNFATDLILQLV-GL +DNVNAHMRELGFTQIHLRHNCWQLLNSQGTLENNVATPADLNRLLVMIGKKEILTPASCD +LMLDILRRQHY-NSRLPYLLPPGTKVAHKTGTVNE-VVNDAGIIYLPDNKGAVAVTVLSR +GIKDKQAAELTIAKVAKAVYD-- +>[subseq from] Beta-lactamase, putative n=1 Tax=Leptolyngbya sp. NIES-3755 TaxID=1752064 RepID=A0A0S3U4P8_9CYAN +--------TAIASQTQLTPGFMIVDADTHAYV-DVNGSNPIPAASTIKFPILVAFFQAVD +EGKIRLDEPLTMRKELVATESGELQNLPGSQFPAIEVATKMIDISDNTATNMIIDRLGGK +DAVNQRFQSWGLTNTAVQNMLPDLPGT------NTSSPRDMVALLDAVNRGELVTMRSHD +RMLSIMRKVVN-NSLLPQGLGEGSAIAHKTGDIGI-MLGDVGMIDLPNGKRYLMAAMVKR +PHND-DRAGDLIRQVSKMTFQYf +>[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. TCA1 TaxID=2682474 RepID=UPI001358A800 +--ALGQQITALGQGFDGDIGIAVEDVQTGAVA-EFDGRTFFPQQSVSKFWVALAALDAAD +RGRIKLDTPVVLTPSDLTLHQPIANEIRTAGTTLGALMSRALQQSDNTCNDFILRAIGGP +GSVRAFIDANNIAGVRFGPGERLMQSAYVADPVDGAQPVAVVNALARLQRGELISASSTA +RLLGTMSHTRTGPQRLKGGLAPGWSLAHKTGTGQQTGYNDIGILTSPGGRSYAVAVMIRR +TAAPIWSRMVVMQNVVRAVIA-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1P492_9ZZZZ +------------------------------------------------------------ +---------------------------------------------DNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Bradyrhizobiaceae bacterium TaxID=2072420 RepID=A0A3S0MFW8_9BRAD +-qDLKSEISRIESRIKGRLGVAVLDTGSDRRF-GYRKDERFPMCSTFKLMAAAAILKRVE +QGQETLEQRVHFSKSDLVTYSPATEKHLESGMTVAELCEAAITLSDNTAGNLMLGMLGGP +PGVTAFARALGDPLTRLDRTELALNEAVPGDP---------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Cylindrospermopsis raciborskii TaxID=77022 RepID=UPI000E1E7476 +----KTTIENLSAANNLIPGVFIVDIDSGGYV-DVSGNKNFSAASTIKIPVLVAFLEDVD +RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIELATKMMTISDNTATNMLISKMGGK +ELLNARFRSWGLVNTAIQSPLPDLEGT------NTTSPKELASLIAKVNQGELISMRSRD +LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR +PH-NEPAAAKLINSISQATYSY- +>[subseq from] Serine hydrolase n=2 Tax=Cylindrospermopsis sp. CR12 TaxID=1747196 RepID=A0A0R0M7U3_9CYAN +----KTTIENLSAANNLIPGVFIVDIDSGGYV-DVSGNKNFSAASTIKIPVLVAFLEDVD +RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIELATKMMTISDNTATNMLISKMGGK +ELLNARFRSWGLVNTAIQSPLPDLEGT------NTTSPKELASLIAKVNQGELISMRSRD +LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR +PH-NEPAAAKLINSISQATYSY- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 3335mG TaxID=2204170 RepID=A0A318ANW1_9NOSO +-----NAVQALGGSFKGQVAIAVRDIDQGWSI-AWNGDKPHPQQSVSKLWVGIAVMAAVD +EGRLSLADPVVVKRSDLTLHQPIRAKVGPEGTTIGDLLQGAMTLSDNTCNDVLLWKVGGP +DAIRRMLAAKGIEGVGFGPGERELQARYLDDPYDGATANGITLGLSLLADNKLLSPASTR +HLLALMRASRTGPLRLKSGLKPGWTLAHKTGTGQSTGYNDIGLLVAPDGRRYAVAVMIAS +TREPIPVRMRLMGDVSRAIVA-- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetia bacterium TaxID=2052181 RepID=A0A4P5WTD2_9BACT +-qTLAERIQPLVQAHRGNAAVAIRHLETGEQF-LWRADLVQPTASLIKLPVMVTACRMAD +AGQLDLSKMLQLSDADKVPGSGILTGHFSAGLSVRDAMRLMIRYSDNTATNLVVREI-GL +PATAACMQELGYAETRLNSFVYRGDTTIAPERSGSTTALETIGLLEQIQRGTAAKPESCQ +AMLQHLESCDD-DTMLAAQLPKGTRIAHKSGAVA-ASRTDAGLIFGPGG-VFAICVLTTE +NEDDNNSAHELIAKVARAAWDHf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9ATQ8_9BACT +-qKLAATVNEMDGKLDGVLAVGILDLSTGQKY-LLHADEVMPTASSIKIAILAELYRQAQ +QSKLKLTDFYTLQQSDRVGGSGITSVFSPGMLTLRDVAGLMISVSDNSATNVIIDRV-GM +ENVNALLDSLGLTHTRLRRKMMDLKAA-SEGRENVANPREMMLLLENLYRGKVLNKQMTE +DFFNLLSVHKE--SYIPHNLPEDVKVANKPGELE-GVRNDSGIVFAGKR-PYVISVMTTY +LRRE-RDGGEAITKISDAAYQMf +>[subseq from] AMIN domain-containing protein n=1 Tax=cyanobacterium PCC 7702 TaxID=1173021 RepID=UPI00036F5DDE +--QLSSEVRKLMSRYNLDPGMFFLDLETGDYL-DINGEKVFPAASTIKFPILVALFEDID +SGRVKLNEILVMRRDLMTGGSGIMQKRPGTKFSLWETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALIVKNQLLSDASRS +RVLDLMSRVEN-KSLLPRGLGKGAIISHKTGTLGI-VLGDAGIIQMPTGRRYLAGIMVRR +PFGD-LAAKSFINQVSHLVYDYf +>[subseq from] Serine hydrolase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E4CUH7_9SPHN +---LDDQLFALGTNLDGKVGIAVHDPARGRMM-HFEGTALYPQQSVSKLWVALTALDQAD +RGELDLSEAGTVRREDLAVHSPIRKSVVANGTSYADFIARALTQSDNTANDMVLRRVGGP +EEVRRTLARKGFADIRFGPGERPMQSAYVADPVDGATPVAIAAALAQLHEGALLSDGSTA +QYLGWLSEVKSGPNRLKGGLPAGWSIAHKTGTGQQAGYNDVGILTAPDGSIYTVAVMIGR +TQVPVPERMEMMHGVVRAIAG-- +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=T0HPJ5_9SPHN +-----SVIRNLGQSFKGKVGIAVRRVGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD +RGKLRLTDTTTLTRNDLTLHQPSAALVAKQGTSYSDLMRRAMTQSDNTCNDALLRAGGGP +DAVRGFLARRMIKDIRFGPGERLLQSNYLSNPPDGAAPSSIVAALAKLKQGDMLSPASTR +LLLNIMSEAKTGPQRVKGGVPAGWHYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTVPIPERWALMQAVSKAVAA-- +>[subseq from] Uncharacterized protein n=1 Tax=Phenylobacterium sp. RIFCSPHIGHO2_01_FULL_70_10 TaxID=1801945 RepID=A0A1G2WJW2_9CAUL +--ALAAYVDALGRNFQGRAGIAVRSLEGGWTA-AHDAEGLYPQQSVSKLWVALSVLDAVD +RQVIRLDDPVLVRRQDLSIHQPIRDFVGPRGTSVDELLESATTKSDNAANDVLMRLVGGP +EAVRAVIAEKELGAIGLADEERYFQTAYLAEPPDGATPVAVVEALERLHRGELLSPESTE +LLLTHLGASRTGPNRLGGGLAEGWTLAHKTGTGQATGYNDVGLLTAPDGATYAVAVMIAE +TTATIPERQALMQAVTRAVIA-- +>[subseq from] serine hydrolase n=1 Tax=Anaeroarcus burkinensis TaxID=82376 RepID=UPI0003FE8F59 +-kHLHTKLEQLAASCPCRWSVVVTDTDGREIY-SLRPDLIYPSASMIKVPILFEILRQAA +AGTLCLQEPLAPSASCRVGGAGILKELNPSLLNIRDLCVLMISLSDNTATNTLIERV-GM +AAVNQTMSDLGLSHTRLQRRMMDFAAA-EAGLQNETTAADMAKLYQLLLNAQGLPPAYAA +LALNILKTQQV-RDKIPFYLPESVSLAHKTGTLD-GVEHDGGVLYLPAG-PYIVCIFADG +LQ-SNAHGLQLIAQMGRAIYN-- +>[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. FGD1 TaxID=2692619 RepID=UPI001367BADD +--ALGQQITALGQGFDGDIGIAVEDVQTGAVA-EFDGRTFFPQQSVSKFWVALAALDAAD +RGRIKLDTPVVLTPSDLTLHQPIANEIRTAGTTLGALMSRALQQSDNTCNDFILRAIGGP +GSVRAFIDANNIAGVRFGPGERLMQSAYVADPVDGAQPVAVVNALARLQRGELISASSTA +RLLGTMSHTRTGPQRLKGGLAPGWSLAHKTGTGQQTGYNDIGILTSPGGRSYAVAVMIRR +TAAPIWSRMVVMQNVVRAVIA-- +>[subseq from] AMIN domain-containing protein n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000C8095E2 +--QLNTQVKALMARYSLQPGMFFLDIDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD +AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS +KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5318 TaxID=2019666 RepID=A0A2N6LAU6_9CYAN +--QLNTQVKALMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD +AGRIQLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS +KTLDIMRRVEN-RSLLAAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] Serine hydrolase n=1 Tax=Leptolyngbya frigida ULC18 TaxID=2107698 RepID=A0A2T1DYC0_9CYAN +----KADLQALALKMQLTPGIFLYELDSSAYL-DLNGGASFAAASTIKVPILIAFFQDVD +AGKIRLDELLTMRKELVAGGSGEMQGPVGTQFTALETVTKMITISDNTATNMVIARLGGM +SALDQRFRSWGLVSTAINSLLPDLSGT------NTTSPRDMALLMTRISQGELVSIRSRD +RVLDIMQRTVN-RSQLPQGLGKGATIAHKTGDIG-GMIGDVGLIDMPSGKRYALTVLVKR +SFND-DSAYDLVQKASRTVYQY- +>[subseq from] Beta-lactamase class A n=1 Tax=Hydrogenispora ethanolica TaxID=1082276 RepID=A0A4R1R8I5_9FIRM +-------ILQAIDPTAMKCGFVIKNLRTDETA-LWNERQRVPSASLIKLPIMAEVLRQAQ +AGSYSLTRRIRVKQEDKVPFSILTLLETGNDYSLQDLITLMIVQSDNTAANLLIDLA-GM +EKVNRFLAGLGLSATLLQRKMMDGTAR-RAGRENFTCAADMARLLELLYREELVDAPSSA +RMLEIMKQQLD-TSMMMLQLPDETVVAHKTGELEQ-IDHEAGIVYLEGRD-YLFVMLVWD +APAN-RDARLAIGRASRAVYDYf +>[subseq from] serine hydrolase n=1 Tax=Prochlorothrix hollandica TaxID=1223 RepID=UPI00034D6A7F +---LKQKVQALVQEQDLTPGVMVVDLDTGDYY-SLNGDRLFATASMIKMPILLAFFEDVD +AGKIRLDEELVMREDLVATEAGEMQYPVGTKFTALETAEEMIRISDNTATNMLIDRLGGA +AALNQRFRDWGLTTMAINNLLPDLEGT------NVSTPQDFALLMELINEGNLLSMRSRD +RLLSILRTPVT-QTLLSPGLGEGATIAHKTGDIGS-LVGDVGLIDMPTGKRYLAVMMVER +PTND-NRAQELIRQMSRLTYG-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingorhabdus sp. TaxID=1902408 RepID=A0A2D5DJP7_9SPHN +----VAEIDELWRNXPGTTGXAVRRXXGDWSF-GKRQDEXXPQXSVSXTWVSLTILXEVD +KGRIKLSDPVTIGVNDLAVHQPIRDRVIANGETVYSLIQQAITRSDNTANDALLWKAGGP +DAVNAFIRXKGLGAIRFGPGERLLQSDYLRDPMDGASPQAIVDALGKLARGELLSPESTR +LMLETMERTHSGPNRLKAGVPDGWDFLHKTGTGQATGYNDIGIMTAPDGTRYAVAVMLGD +TTASIPARMRLMQSVTRAVARY- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides sp. An269 TaxID=1965613 RepID=A0A1Y4FJB9_9BACE +---LQEQIQQITANTDAHVGVALI-IDGKDTI-TINNDDRYPLMSVMKYHQALAVAHYLD +KHHLPLSTSVFIRKEDLRPYSPLRDRYPEGNLPISELLTYTLQLSDNNACDILFDYIGGT +EETDKYLRTIGCDQFAVTATEDDMHKNLALCYNNWSTPLSTARLMDRLAAETLIDTSYTH +FIRETLLDCQTGKARLPFPLQTETRIGHKTGTSDQNGINDAGFILLPNGKRYTLVVFVKH +SKLSFEATERVIADISAVVFR-- +>[subseq from] Uncharacterized protein n=1 Tax=Rhodopirellula sp. SM50 TaxID=595453 RepID=A0A2A2WH76_9BACT +-dDLDRRITPLIGPYQGDVAVGIKNLSGEGEF-WYRHEQPMATASLIKLPLLVTTYQQID +SATVDPAQLIELTREDKVPGSGILTRHFSPGLPLIDAIRLMIRYSDNTATNLVIDQV-GL +PTTTETMKSLGLLHTQLHAKVYRRDTRSQRYGLGSTSAADMITLLEGIHTHQVASKSSCE +AMIAHLLSCDD-QVKLPAGLPSGTKIAHKTGGVSS-VRTDAGIIYGPGKQAFAICVLTEN +NKSAESAPHRLIADIGRAAFDVf +>[subseq from] Class A beta-lactamase n=2 Tax=Bacteroides TaxID=816 RepID=A0A1Y4E643_9BACE +---LQEQIQQITANTDAHVGVALI-IDGKDTI-TINNDDRYPLMSVMKYHQALAVAHYLD +KHHLPLSTSVFIRKEDLRPYSPLRDRYPEGNLPISELLTYTLQLSDNNACDILFDYIGGT +EETDKYLRTIGCDQFAVTATEDDMHKNLALCYNNWSTPLSTARLMDRLAAETLIDTSYTH +FIRETLLDCQTGKARLPFPLQTETRIGHKTGTSDQNGINDAGFILLPNGKRYTLVVFVKH +SKLSFEATERVIADISAVVFR-- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides sp. An19 TaxID=1965580 RepID=A0A1Y4JEQ3_9BACE +---LQEQIQQITANTGAHVGVALI-IDGKDTI-TINNDDRYPLMSVMKYHQALAVAHYLD +KHHLPLSTSVFIRKEDLRPYSPLRDRYPKGNLPISELLTYTLQLSDNNACDILFDYIGGT +EETDKYLRTIGCDQFAVTATEDDMHKNLALCYNNWSTPLSTARLMDRLAAETLIDTSYTH +FIRETLLDCQTGKARLPFPLQTETRIGHKTGTSDQNGINDAGFILLPNGKRYTLVVFVKH +SKLSFEATERVIADISAVVFR-- +>[subseq from] Serine hydrolase n=1 Tax=Virgibacillus necropolis TaxID=163877 RepID=A0A221MAB5_9BACI +-kQLINSIESITKQAGGTWGISLDDLDKKETW-TSNEDELFYAASVIKVPILLAAFTAFD +QRKFSLSDTVKLRKEDLVGGSGVLQHMTPGTLTIYDLVTLMIIQSDNTATNMVIDLV-GT +KKIQQTMEDLGLENSRFYNKLMVVPANLEG--RNLVTAADMTSMLKQMVMGEVVSMHACE +QMIDMLKKQQL-QNCLPARLPEQWELAHKTGSISR-VCHDIGILYVGNRT-MVVSILSKG +VE--DRTSPKVIADIGWEIYHY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium cloacae TaxID=120107 RepID=A0A1E1F2Y7_9SPHN +-----SVIRNLGQSFNGHVGIAVRRIGADWTV-AHNGNQLFPQQSVSKLWVSMAFLDAVD +RGKIRLSDTTTITRKDLTLHQPSAALVGNNGTTYSNLMNRAMTQSDNTCNDALLRAVGGP +DAVRGFLARRFIGNIRFGPGERLLQSNYLANPPDGAAPASIVQALAKLKEGDMLSPTSTR +MLLSVMGEARTGPQRVKGGVPPGWHYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS +TTEPIPVRWQLMQAVAKAVAA-- +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Scytonema sp. HK-05 TaxID=1137095 RepID=A0A1Z4IKD0_9CYAN +--QLNSQLKTLIARYSLSPGIFFLDLDTGNYL-DFNGEKVFPAASTIKFPILVALFQEVD +AGRVKLNETLVLRRDLKAEGSGVLQYPVGTRLSVLDTITKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALITNNKLLSDRSRS +QALGIMRRVEN-RRLLPAGLGKGAVIAHKTGTLGV-LLGDAGIIELPSGKRYLAGILVKR +PFGD-TRARVFISQVSKLVYG-- +>[subseq from] Beta-lactamase n=2 Tax=Thermoanaerobacterium TaxID=28895 RepID=W9EEV2_9FIRM +--SLHDDIMNFISNADGDIGVSVKNLKTGEII-SVNEDMMFPSASTIKILIMAQIYKMAK +EGYIRLTDNIVLSDFMKTDGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM +KNINKMAEDLGLVNTKIQRKMMDFEAA-KSGKDNYTCPKDMTRLLEQMYSGKVVDEEYSI +KMIEVLKKQQD-LGRLDMYLPDDIVIAHKPGELKS-LEHDVGIVFLKDCD-YIISVMTNN +MTT-NLDGKIAIGKISKMVYDEy +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf38 TaxID=1736217 RepID=UPI0009E74562 +-----NAVQALGARFDGQVGISVRDIDENWGV-DWQGDTPRPQQSVSKLWVAIGVMDAVD +RERLSLGDPVTVTRADLTVHQPIRTLVGKTGTTVGDLLRGAMTRSDNTANDVLLWRIGGP +AAVNRMLRDKSVTGVRFGPGERQLQARYLDAPLDGASANGVTLGLSLLAQGRLLSDRSTA +PLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS +TRQPVPVRMRLMGDVTRAVIA-- +>[subseq from] Uncharacterized protein n=1 Tax=Omnitrophica WOR_2 bacterium RIFCSPLOWO2_02_FULL_45_28 TaxID=1801864 RepID=A0A1G1PQ67_9BACT +-qALQQSIKSEIGQFKGEAGIVIKDLGTGWEF-SYEKAKLFPSASLAKIPLMAACFLAVD +QGRIKLDRNIALKSADKLTGSGVLKDMPAGTFSVERLIGLMIYDSDNTATNIVTNLV-GI +DYLNNTFKSFGLKNTDLSRKIADYHSR-DKGIENYTTAEDMALLLDKIYRRSLGNKNVSD +QCISMLKLTRM-NDRIPKYLPVDITIAHKTGLEN-GVCHDAGIVFTNKGD-IIIVVLTKH +ANSNSAPSKGFIAKVSLHAYRYf +>[subseq from] serine hydrolase n=1 Tax=[Scytonema hofmanni] UTEX B 1581 TaxID=379535 RepID=UPI0004953D09 +--ALNSQIKALMNRYRLNPGMFFLDLQTGNYV-DINGEKIFSAASTIKFPVLVALFEEID +AGRIKLNEKLVMRRGLIANEAGTMQKPVGTKFSVLQTVTNMMVTSDNTATNMIIDRLGGE +TKLNQRFRNWGLQNTVIRNNLPDIGGT------NTTSPKDLVRLSALLTNNRLLSPQSRN +QVLAIMRRNHN-RSLLPAGIDKKAVIAHKTGTLRF-ILGDAGIIQMPNGKSYLAGILVRR +PNHD-DRAMYFIRQVSRAVYNY- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Bathyarchaeota archaeon TaxID=2026714 RepID=A0A550H166_9ARCH +----IDAIKKPAEGFKGKLGVSVKHLGTGESA-DLNGDMLFPTASVFKVPVIVEFYRQVE +DCMIGLDDQVLLRDSDKVPGSGILKELTEGLVSYRDLLSLMMIVSDNTATDLIVKTV-GF +DNINDAMKDLGLKDTKVTKYCRQILFSLGTEDNDITTPNEMLKLVEYIVEGKAAEPESCQ +AILDIMAKCQTGGYRIPKYLPNKLLLQRKTGSLP-GVRNDVGVITVKTGEKYILACFTMD +AE-DNYEAEEVIAKVSQAVYQYf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Mn802worker TaxID=629773 RepID=UPI0012EAE697 +--DLVNAVQALGSGLKGDVGISVRDIDDGWVV-AWQGDRARPQQSVSKLWVAVAVMDAVD +RGTMSLSDRVTVRRSDLTLHQPIRALVGKEGTTVGALLRGAMTRSDNTCNDVLLWRIGGP +AAINRMLAGKGIVGVRFGPGERKLQARYLAAPMDGASANGITLGLTLLAQGKLLTPRSTA +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS +THQPIPARMRLMGNVTRAIVA-- +>[subseq from] Serine hydrolase n=1 Tax=Fischerella muscicola CCMEE 5323 TaxID=2019572 RepID=A0A2N6K958_FISMU +--QLNTQVKALMARYSLQPGMFFLDIDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD +AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFQSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLSALLTNNQLLSDTSRS +KALDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sp. SYSU K30005 TaxID=2666135 RepID=UPI0012D8875B +---LQESLEKIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVQ +IGKVELKERIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK +ENVNQYMKEIGLSNTYIRLSCWELLCFQESHANNVTTAADMALLLEQIANKQLISEKACD +DMFEILAKQQF-RNRIPYLLPQNTVVAHKTGTLAS-VVNDAGIVQLPDNGNFIITVFSIG +NK-TEAEGASIITKLSRVTYNHf +>[subseq from] Beta-lactamase n=1 Tax=Aphanizomenon flos-aquae 2012/KM1/D3 TaxID=1532906 RepID=A0A0B0QIH7_APHFL +--ELQTPIKTLMARYKLSPGIFFMDLNTGDYL-SINGDKSFAAASTIKYPILVALFQQVD +AGKIQLDETLVMGKKHIVGGSGNMQYRLGSKFSLLETATRMMTISDNTATNMIIDRLGGI +TQLNQKFRSWGLQNTVMRNRLGDFQGT------NKTSAKDLVKLSALMENNQLLSNTSQL +QVIGIMNGCHN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETPSGKRYLAGVFVQR +PNND-PRGTDFIRQVSQVVYGYf +>[subseq from] Uncharacterized protein n=2 Tax=filamentous cyanobacterium CCP2 TaxID=2107700 RepID=A0A2T1CV85_9CYAN +---LLQKVTPIAQGTDLTPGVFVLDLDNGDYL-SLNGETTFSAASMIKVPLLLAFFQDVD +SGKIRLDEMLTMLEGDIVGEAGEMQFDGAGTYTALETAANMIITSDNTATNMIIRRLGGV +EVVNQRFREWGLQQTVLRNPLPDLEGT------NETSPRELSYLLARVSEGELMSMKSRD +RFLDIMERTVA-NGLLPASIGQGATIAHKTGDIGS-LLGDSGIVDMPNGKRYAITVMVKR +PHND-DRAFELIRQISGVTYDH- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. MK52 TaxID=2711156 RepID=UPI0013EA8A6D +---LDRTIARLGRSFDGDVGIAVRDVQTGWTS-DHRGLDLFPQQSVSKLWVALAAFDQVD +RGTLSLDRELSLTKADLTLHQPVRALALRPGTDARDLVIRALTQSDNSANDRMLREVGGT +GSIRATLAAKAIAGVRFGPGERSLQAAYTSDPMDGASPLGIVDALARLKQGRLLSQRSTE +EMLGIMSNTRTGANRLKGGLEPGWTLAHKTGTGQQAGYNDVGILTSPEGRSYAIAVMIGR +TDRPLGQRMALMQKVVGATID-- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0012460585 +--ETLVKVKDAEAQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Olivibacter sitiensis TaxID=376470 RepID=UPI000405A205 +--ALRKKIEGLMEKHKGRFAVAFKDLTTGETF-LHDAHKNFHAASTMKTPVMVEVFRQAS +LGKFSVDDSILVYNRSIVDGSYYSYKKVGTKLPISDLLYRMITKSSNLATNIVIDLV-GA +KNVNKTMRAMGAKDIQVLRGVEDSK-AYEKGLNNTTTAYDLMLLFEQLAEENIIDKASCD +RMIEILMDQHF-RSKIPALLPEGVRTATKTGSLAT-VSHDSGVVFLPDGRKYVVVLLSDG +ID--KEEADKTLAQISRALYDY- +>[subseq from] Serine hydrolase n=1 Tax=Pseudanabaena sp. TaxID=1153 RepID=A0A2W6YT59_9CYAN +--SLTAKIKELAAQKDLVMQMMAIDLDSGTYV-QVGATQKIAAASTIKTPLLVAFFQDVD +AGKIKLDELLEISEDVMVGEAGDFQGPLGTKKTALETATQMIVISDNTATNMIIKRLGGL +AAVNQRFQSWGLNNIVANNKLPDLEGT------NTISTQDMVTILAMVSQGKLMTPRSRD +RFMDIMSRPIT-RTLLPQGIGADARIFHKTGDIGS-AVGDAGIIDMPNGKRYAIAVMVTR +PNND-QRANELIRQISRASYDYf +>[subseq from] Beta-lactamase n=1 Tax=Calothrix sp. PCC 7507 TaxID=99598 RepID=K9PN19_9CYAN +--ELQTPIKALMARYRLTPGIFFMDLQTGDYL-NINGGKAFPAASTIKYPILIALFQEVD +AGKIKLSETLVMQRKHVAGGSGNMQQRVGTKISLLETVTKMMTISDNTATNMIIDRLGGK +ANLNQRFRSWGLQSTVIHNMLGDFKGT------NKTSAKDLVRLSALMANNQLISDTSSS +QVLGIMIRCHN-RSLLPSGLGSGASIAHKTGTLRF-VLGDAGIIETPSGKRYLAGIFVRR +PNND-DRAKAFIRQVSQVVYGYf +>[subseq from] class A beta-lactamase n=1 Tax=Parabacteroides merdae TaxID=46503 RepID=UPI000EE076FD +---IENTLQEYIAGKDARIGVAVI-INSKDTV-SINGNRDFPMMSVVKFPLALTVAHWID +NNDMSLNDSIAFGENDLNEYSPMLKMYGKSRMTVRELFEWSLVESDNNAADILLKRIGGT +SGATSLMRQLNISEILIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYIEMRNTSRSYS +EISSMLEQCSTGRDRLAALLPINATIGHKTGTGFISAVNDCGYVKLPDGTRYSIAVFVAD +SSYDMAATSAIIAEISNIVWK-- +>[subseq from] Beta-lactamase n=2 Tax=Bacillaceae TaxID=186817 RepID=A0A0B1Y3E8_9BACI +---LQENLEKIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVQ +MGKVELKERIRLEEEDLVNGSGILKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK +ESVNQYMKEIGLSNTYIRLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH +DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGNFIISVFSIG +NN-TEAEGASIISKLSRVAYNHf +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonas sp. SM23_52 TaxID=1703359 RepID=A0A0S8H5A1_9BACT +--ELRSRLQSRISESGAEVGVYFRNLASGDSL-LLDVESRVHAASMMKVPVMIQLYRDAE +AGRLSLDDSLTISKTSIVDGTPYEYARVGEKETVRQLTELMITVSSNLATNMLIELV-GA +ERVQATMRQLGADSIAVLRGVEDIK-AYRAGLNNTTTARDMGLIFSAIAEHRAASPESCR +EMIAILSRQQF-NEGIPAGLPPGTQVAHKTGSIM-GIRHDGGIVYPENGSPYVLVVLTRG +IT-DSASADRLITDVSRMVYA-- +>[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc sp. PA-18-2419 TaxID=2575443 RepID=UPI0011084EB2 +-----SQIRTLLASYSLNPGIFFLDLDTGNYI-DINGEKRFAAASTIKFPLLVALFQEID +AGRIKLTDKLVMRRDLRVGEAGTMQKPIGTKFSVLETATLMMTISDNTATNMVLDRLGGA +AKVSQRFRSWGLQNTAIRNLLPDIPGT------NTTSSKDLVRLAALVSNNRLLSPNSRN +QVLGIMRHVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIKMPNGKSYLAGVLVQR +PNYD-PKAGDFVREVSRRVYNY- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0012476115 +--ETLVKVKDAEAQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=candidate division TM6 bacterium GW2011_GWF2_28_16 TaxID=1619077 RepID=A0A0F9YC03_9BACT +-kQLQKNISEKCNSLTGLIGVSAYHIESKKWV-NCNADEFYPMASTYKLQIAAYCLSLVD +KKQINLQEKYKIKTLDLQRGSTIKK---GQQMSIAELIKLMIEKSKNDASDIILRMVGGP +DHVNNWLKTNGFNNMSVDRSVLEMLDKFYVDKKDTTTPKEMVNFLTQLFEKKLLSEDSTN +FLLQSMLKCHWGKEKIPGLLPQGTKIWHKTGRMDK-ITSDVGIVELPNKGHLVIALYTNK +SKSSIDIQERKMAQISKLLFDYf +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPHIGHO2_02_FULL_61_10 TaxID=1797944 RepID=A0A1F9XDK2_9BACT +--RMSQDMRRAVRTFQGGVSIYVKNLETGKEW-AYNADEKMPSASLIKLPIMIGVVEKIG +KGELSLDHPMVLTREARRSGSGHIKWRPNGEFTIGQLLEEMMAYSDNIAQELLIRAV-GM +KYLRERFAAFGLTATNITREGLSLA--PRTRIENYTTAREMGMLLEQIYRGQKFGGDSSA +RMIELMKHAKY-NDRLPRQLPAGWTIAHKTGLLRR-ACHDCGIVYSPAGD-YIICVLTRS +GR-SYRDAKRFISKVAAISYRYf +>[subseq from] HGF-1 beta-lactamase n=1 Tax=Alistipes sp. CAG:831 TaxID=1262698 RepID=R5ID00_9BACT +-kDLRGDIEKVIAGRQATIGVAVMC---GDTViTVNNSRKYPLMSVFKLHVAVTALRKMD +AEGIPLDSTVLIRSEQLHEYSPLRDRYPGQDISYRNIVGYTVSHSDNNTCDLLIGFSGGI +DKVDSCIKSLGITDLNLTETEADMHGDIRNGYLNWSTPMSVVRLFEKIYSGEILSTEHSA +FLERILLECSSGQDKLKAGLPGDVPVAHKTGHSDRLGDADAGAIYMPDGRKCYVSVLIMD +SKETDEVNAGVMAEIAGIVYRYf +>[subseq from] serine hydrolase n=1 Tax=Acaryochloris sp. CCMEE 5410 TaxID=310037 RepID=UPI00058532A0 +---IKRQIQAWAAQSELKPAMFFLNPSTGEYL-DINGAKSISAASTIKIPVLLAFFEDVD +AGIIDLDEPLVMRPDLVASEAGSMQEPVGTTFSALDTAEYMIAISDNTATNMLIDRLGGA +KKLNQRFKSWGLKHTTIRNPLPDLEGT------NTISPQDMAALMLKLKDEDLLSSISRE +QALDILRQTVT-NTLLPQGIDKDADIAHKTGDIGS-VVGDIGLIDMPNGQHYVAAILVQR +PHND-PRAQELIRKISKLTYKTf +>[subseq from] Uncharacterized protein n=2 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A350CFW2_9PLAN +-qTLAERIQPLVQAHRGNAAVAIRHLETGEQF-LWRADLVQPTASLIKLPVMVTACRMAD +AGQLDLSKMLQLTDADKVPGSGILTGHFSAGLSVRDAMRLMIRYSDNTATNLVVREI-GL +PATAACMQELGYAETRLNSFVYRGDTTIAPERSGSTTALETIGLLEQIQRGTAAKPESCQ +AMLQHLESCDD-DTMLAAQLPKGTRIAHKSGAVA-ASRTDAGLIFGPGG-VFAICVLTAE +NEDDNNSAHELIAKVARAAWDHf +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Alistipes dispar TaxID=2585119 RepID=A0A4Y1WYF7_9BACT +-dDLEHRLDEALEGRRARIGVAVR-TPDGRTI--RRGDVPLPLLSVFKVPVALAALDRAA +RERMPLSAPFDVGPERLDGYSPMRDSLPPEGVTLAGLIRYSISLSDNIACDRLLDFAGGP +AAVEEYLRGAGIGGFRIAASERTMHRATENQRLNTAPPSAVCELFARLLRGGLLPAEYDA +LLRSALEEAPTGANKLRAGLPGNVRLGHKTGSSDRTADNDAGYVLLPDGRSYCVAVFVTD +SRETDGTNAAIAAEISRAAYECf +>[subseq from] serine hydrolase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI0009EB640E +--DLLNAVQALGAGFEGQVGISVRDIDENWVV-DWQGDTPRPQQSVSKLWVAIGVMDAVD +QGRLSLADPVTVTRADLTLHQPIRTLVGKTGTTVGDLLRGAMSRSDNTANDVLLWRIGGP +AAVNRMLKDKGVASVCFGPGERQLQARYLDAPLDGASANGVTLGLSLLAQGRLLSDRSTA +SLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS +TRQPIPARMRLMGDVTRAVIA-- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. HI0020 TaxID=1822223 RepID=UPI0012E778F1 +-rELDQAVSRIGGTFDGHVGIAVRDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD +AGRLDLSEMVAIRNADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA +EAVQDFLDTHELASIRFGTDERSKQSSYLADPIDGAPPVALVEALARLQRGELLSAGSTG +LLLGTLARTKSGPQRLKPGAPEDWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR +TREPTPVRMEMMQQVVRAVAR-- +>[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium UBA11371 TaxID=2055770 RepID=A0A351LFT6_9CYAN +----KAEITAALAQYQLTPGIFILDPDTDAFL-DLNGSSAKSSASTIKIPILVAFFQDVD +AGKIRPDELLTMKAKFIAAGSGNMQKFPGSKYTALETATKMIAISDNTATNMLIERLGGA +EALNQRFVSWGLTATAIRNQLPDIEGT------NTTSAKDLASLIAFVNQGELLSLQSRD +RLLSILRRTER-NHLLPRGLGAGATIAHKTGYIG-AMLADAGLIELPNGKRYIAAVMVKR +PRND-PQAEKLIRQISRIAYQHf +>[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Apibacter muscae TaxID=2509004 RepID=A0A563DFA6_9FLAO +-----DSIQNVIKDKQATVGVGVIY-HNNDTL-SINNQYLYPTMSVYKFHQALAILNYLE +KNKLSLNTTYFIKKEDLDPYSPLFKERPEGNISIKDLLYYSICLSDNNVSNYLFRYLVNP +AQTEDYIKSLGTDEISIKRTEKEMSQNHDNQYLNWTRPLATAILFNKILNEKIFKEEYQD +FLIETLIKTNTGENKIKGLLPKDLIVGHKTGNSYRDADNDAGFVLLPNGKKYTLAIFIMN +SKETDEVNASIIAKISQLIYNYy +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. OV641 TaxID=1881068 RepID=A0A1H6X2Z6_9SPHN +--ALLNAVQALGRGFSGDVGISVRDIDEGWTV-DWAGDKPRPQQSVSKLWVGITVMDAVD +RGRMSLSDPVTVRKSDLTVHQPIRPLVDSDGTTVGALLQGAMTRSDNTANDVLLWRVGGP +EAVRRMLDDKDVAGVTFGPGERLLQARYLADPEDGASANGVTLGIALLAQGKLLSPASTD +KLLSLMRASRTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPNGHRYAVAVMIAS +TRQSIPSRMRLMGDVSRAIVA-- +>[subseq from] serine hydrolase n=1 Tax=Oscillatoriales cyanobacterium MTP1 TaxID=1751289 RepID=UPI0009EB7316 +--ALTNSIQNLIAQNGLTAGVYLVDQDNGNYI-DIGGAAALQAASTIKVPVLVAFLQDVD +AGKIRLDEELPMLESDVAEGSGEFQQAVGTKWTALETARQMIVISDNSATNMLIRRMGGA +QALNQRFRSWGLTATVINNPLADLAGT------NTTSAKDLTTLLTAVTQGKLLSLRSRD +RLMEIMQSTVT-NTLIPAGIGEDVLVAHKTGNIDT-MVGDTGIVDMASGKRYVLTVLVQR +PV-DDSRAQELIRQISNAVYQYy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A166NHK6_PSEAI +------KLAELERQSGGRLGVALIYTADYSQI-LYRADERFAMCSTSRVMAAAAVLKKSE +SEPNLLHQRVEIKKSDLVHYIPIAEKHVNGTMSLAELSAAALQYSDHVAMNTLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLR-------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9VUU2_9BACT +-eKLTASIRQVDVELDGVLGVAIEDLTTGQKF-SLREDEVFAQASSIKIAVLAELYRQDQ +SGKAKLSDLYTVQASDLVPDSDIMGGLTPSVITNRDLATMMVAVSDNSATNVLIDRV-GM +ENVNRMLDSLNLPHTRLRRKMMDIKAA-AEGRENISTPREMLSLLEQIYRGKVLNQETTQ +EFLKMLSTHK--DSWLPRDLPDSVRVADKPGSLE-GVRNDSGIVFAQNR-PYAICVMTSY +LNK-ERDGENAISRISAAAYAVf +>[subseq from] serine hydrolase n=1 Tax=Spirosoma panaciterrae TaxID=496058 RepID=UPI00036E13CD +--ELRQQIEQELARHPGVFAVAFKDLTTGQEL-LIREKERFHAASTMKTPVMIEVYRQQA +QHKLALTDSILVKNESIVDGSPFSYKQLGTKRTLASLVYDMITVSSNLATNLIIEKV-DA +RKVTQTMRELGAKDIEVWRGVEDAKA-FAKGLNNTTTAYDLMVIYEKLAQGKVVSPEASQ +AMIGILLEQKF-NESIPAKLPKDVKVAHKTGSIT-GVRHDSGIVYLPDGRTYVLVILSKQ +IKEDLE-TQNAMATVSEW----- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A7U968_ECOLX +---------------------------------------------------------ESE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVG--------------------------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. BK235 TaxID=2512131 RepID=A0A4R2PJX4_9SPHN +---LLNAVEALGQRFPGAVGISVRDVERGWTV-SWQSGTRRPQQSVSKLWVALATFDAID +RGTLSLRKTVTVRRADLTLHQPIRARVGAGGITIAGLLDCALTRSDNTCNDVLLRQVGGP +AAVRRTLTRKGISGVTFGPGERLLQARYVASPPDGASADGVTLGLARLAQGRLLSKASTA +RMLALMRASRTGPLRLRSGLGRGWTLAHKTGTGQATGTNDVGLLTAPDGHRYAVAVLIAR +TRAPLRVRLRLMGDVTRAVVR-- +>[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI001444F1FD +--ELQTPIKTLMARYKLSPGIFFMDLNTGDYL-SINGDKSFAAASTIKYPILVALFQQVD +AGKIQLDETLVMGKKHIVGGSGNMQYRLGSKFSLLETATRMMTISDNTATNMIIDRLGGI +TQLNQKFRSWGLQNTVMRNRLGDFKGT------NKTSAKDLVKLSALMENNQLLSNTSQL +QVIGIMNGCHN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETPSGKRYLAGVFVQR +PNND-PRGTDFIRQVSQVVYGYf +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Lindowbacteria bacterium RIFCSPLOWO2_12_FULL_62_27 TaxID=1817870 RepID=A0A1F6LAM5_9BACT +--RMSQDMRRAVRTFQGGVSIYVKNLETGKEW-AYNADEKMPSASLIKLPIMIGVVEKIG +KGELSLDHPMVLTREARRSGSGHIKWRPNGEFTIGQLLEEMMAYSDNIAQELLIRAV-GM +KYLRERFAAFGLTATNITREGLSLA--PRTRIENYTTAREMGMLLEQIYRGQKFGGDSSA +RMIELMKHAKY-NDRLPRQLPAGWTIAHKTGLLRR-ACHDCGIVYSPAGD-YIICVLTRS +GR-SYRDAKRFISKVAAISYRYf +>[subseq from] Serine hydrolase n=1 Tax=Larkinella rosea TaxID=2025312 RepID=A0A3P1BNF5_9BACT +--------------AQARVNVAFESLTDHTTF-VHLPDELVPSASVIKIPILIETMERVK +AGKFDLDQIHVLQASEKTGGSGVLQTYPDQSITNREVLTLMMTRSDNSATNILIREL-GM +ENINQRMRTLGLTQSRLNRMMMDTLAA-KQGRENRVTASEMNILLKKIYRNEVATPALCE +QMIDILKRNTD-QTTFRLFLPKSAVIAHKTGELSY-VRGDAGIFYVT--KPFLLTVFVQG +TT--TPEAEKIIGEIAEICYNQf +>[subseq from] serine hydrolase n=1 Tax=Fischerella muscicola TaxID=92938 RepID=UPI00036C4972 +--QLNTQVKALMARYKLQPGIFFLDLDTGNYL-DLNGEKVFPAASTIKFPILVALFQEVD +AGRVKLNETLVMRRDLMTGGSGTLQKRPGAKLSVLETATKMITISDNTATNMIIDRLGGK +ARLNQRFQSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLSALLSNNQLLNDASRS +QALGIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V573_9BACT +------------------------------------------------VMAAAAVLKQSE +TQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP +DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGGTQRA +QLVMWLKGNATGAASIQAGLPTSWVV---------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Nostoc sp. PCC 7107 TaxID=317936 RepID=K9QL89_9NOSO +--ELRSQVKALAARYSLDAGMFFLDLETGNYL-DLNGEKIFPAASTIKFPILVALFQEVD +AGRVKLNETLVMRRDLVTGGSGEFQKRAGTRFSLIETVTKMITISDNTATNMVIDRLGGK +AKLNQRFRGWGLQNTVVRNLLGDFKGT------NTTSAKDLVRLSALVAKNQLLTDSSRS +KVLDIMRRVHN-TKLLPAGLGKGAVIAHKTGTLGI-VLGDAGIIQMPSGKRYLAGIFVRR +PFNDL-KARDFISQVSRIVYG-- +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter aquaemixtae TaxID=1958940 RepID=UPI00135F4352 +--ALDNALFAAANGFDGYLGVAIHDIARDRTV-HYNGERLFPQQSLSKLWVALAALQKVD +EGTLELAEPVSIRRSDLTLHQPVRKIVLARGTDYGDLLRRAITESDNTANDMLLKRVGGP +PGVRNAIAAAGLGAIKFGPGEREMQSAYVLDPVDGASPVAIADALGKLAKGELLEAPTTA +HFLDLLANVKSGPNRLKGGVPAGWLIGHKTGTGQQAGYNDVGILTAPDGSRYAVVVMIGR +TAVPVPQRMELMHAIVAATVHY- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=UPI00068B092B +---LQENLEKIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVQ +MGKVELKERIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK +ENVNQYMKEIGLSNTYIRLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH +DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGNFIISVFSIG +NN-TEAEGASIISKLSRVAYNHf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. (strain YBL2) TaxID=484429 RepID=A0A0C5XQP9_SPHYB +--DLLNAVEGLGQSFKGEVGISVRDLDEGWTV-SFNAERMLPQQSVSKLWVAIAVMDAVD +RGTLSLSDPVMVKKSDLTVHQPIRSLVTKAGTTIGKLLELAMTRSANSCNDVLLWKVGGP +QAIRAMLKRKGLDDVGFGPGERKLQARYLADPYDGASANGVTFGLMRLKQGKLLSGRSTR +HLLGLMRASRTGPQRLRSGLRKGWTLAHKTGTGQATGYNDVGILVSPDGNRYAVAVMIAS +TRLPIPARMRLMGNVTRAIVR-- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI0004A7EE3A +--ELQESLEKIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVQ +MGKVELKERIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK +ENVNQYMKEIGLSNTYIRLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH +DMFEILAKQQF-RGRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGNFIISVFSIG +NN-TEAEGASIISKLSRVAYNHf +>[subseq from] class A beta-lactamase n=1 Tax=Bacteroides uniformis TaxID=820 RepID=UPI00110702DD +-kAIENTLQKYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWID +TNGMSLNDTVTFNEKAMKEYSPMLKKYGKSRMTVRELLEWSLAESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYRELGNASQSYS +EISVMLEDCRTGLDRLALLLPTNATIGHKTGTGFISAVNDCGYVKLLEGTKYSIAVFVAD +SGYDMAATSAIIAEISKIVWK-- +>[subseq from] Serine hydrolase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E7UG09_9SPHN +---LDDRLFALGTGLEGKIGIAVYDPARSRMM-HYNGTQLFPQQSVSKLWVALTALDQAD +RGELDLSETGTVRVDDLAVHNPIRRSVVANGTTYRDFLERALTASDNTANDMVLRRVGGP +DEVRETLARKGFADIRFGPGERPMQSAYVADPVDGATPVAIASALARLHGGELLSQESTA +RYLAWLDDVKSGPNRLKGGLPEGWSIGHKTGTGQQAGYNDVGILTAPDGSIYTVAVMIGR +TQVPVPARMEMMHGVVRAVAG-- +>[subseq from] Beta-lactamase n=1 Tax=Fischerella thermalis TaxID=372787 RepID=G6FSV8_9CYAN +--QLNTQVKGLMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD +AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS +KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] AMIN domain-containing protein n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000C7FA3F8 +--QLNTQVKGLMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD +AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS +KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] AMIN domain-containing protein n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000E0A69E7 +--QLNTQVKGLMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD +AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS +KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001249161E +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0012449D71 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00124942E2 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001248DF18 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001247D821 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0012453F42 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00124565A1 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. YH-07 TaxID=2182384 RepID=A0A345YAX9_9SPHN +---LAREIAMLADGSNGRIGVYAVDLATGHEV-GVLADQRFPMASTSKVAIAAAYLAGVD +EGRWSLTSEFRLPR-------------PGGALPAYKHLSLMISKSCNDCTDALLAAVGGP +RAVNKWMRNAGIEGFELSRDIRTLIRAWSVDAKDSATPRAMGQLLAGIYQGKWLSDHSRR +FLLDAMEETTTGKRRMRSALPVSANLAHKTGTLSR-TASDIGIFHTPDGRAIAAAIYVTG +QSPSMA----------------- +>[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5201 TaxID=2019672 RepID=A0A2N6N4E0_9CYAN +--QLNTQVKGLMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD +AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS +KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001243F231 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001247EF42 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001245CCCA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0012473325 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001245FBB3 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=2 Tax=Candidatus Saganbacteria TaxID=1703751 RepID=A0A1F4RBG8_9BACT +-tKLRQKLDALVLPYGVKVGLCFIDLQNGKEL-QINGKNKFPAASVAKLPVMATGFHLAE +SGKLDLGQKVKFKEKDKLAGSGVLRWMKAGNYTIKNLIRLTIVLSDNTATRMAVRQI-GL +EEINNYLKKCGLNDTVIVDDTM-LNDPALTQNYNTTTPYDMARLVALIKNSAYFSAASKK +QMLAYMKFQRY-RWGLWKGVPKGIKIANKTGNLDR-VLNDVGIVYAPSGN-YALAIFTHG +FQKN-KTARKVINEISKVVYTVf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A5N8ACR8_9SPHN +--ELQRSIAALGQNFNGVAGISVRRVDADWEV-SYNGGRLMPQQSVSKLWVAMTMLDAID +RDRLTMSDPVTISGNDLTLHQPVAAMMKGGTTTLSDLYNRAMQQSDNTANDAILRKVGGP +EAVRGFLARRFIPDIRFGPGERLLQSDYLANPPDGAAASSITLALAKLKRGEMLSPSSTA +YLISTMEGAKTGPQRIKGGVPAGWRYGHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTAAIPERWQLMQGVSRAIAA-- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Melainabacteria bacterium TaxID=2052166 RepID=A0A2W4IK62_9BACT +--SLEDELEKLSDKKKLRTGLFVVEPATGRYA-EMNGRQPFMAASMIKVPVLVSLLAALD +RKSVSLTEKLTIRKDLITGGSGYLQWRPVDSITVKEAAELMIIISDNTATNLLIDRLGGL +EKLNKQYSSWGLKNTKLNNLLADLDGT------NTTSPYDLCYMMGRIERGELISQSSRD +WMYSIMHRTRI-KTLLPQGLNPGDRIFHKTGDIGK-MVGDVGLVHTKDGKRYLVAVQVER +PHND-RRANELIRTLSRAIH--- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00098FF2FE +------------------------------------------------------------ +------------NKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Sphingomonas dokdonensis TaxID=344880 RepID=A0A245ZTW4_9SPHN +--ALLNAVQALGQSFDGDVGISVRDVDDGWVV-AWAGDKPRPQQSVSKLWVGITVMDAVE +KGRLTLDDPVTVRRSDLTVHQPIRPLVKGDGTTVGALLSGAMTRSDNTANDVLLWRVGGP +EAVRRMLADKGVRGVTFGPGERLLQARYLADPIDGASANGVTLGIALLAQGKLLKPASTD +KLLSLMRASKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS +TRQPIPARMRLMGNVSRAIVA-- +>[subseq from] Penicillin-binding protein, transpeptidase n=3 Tax=Cylindrospermopsis raciborskii TaxID=77022 RepID=D4TIF5_9CYAN +----KTTIENLSAANNLIPGVFIVDIDSGGYV-DVSGNKNFSAASTIKIPVLVAFLEDVD +RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIEVATKMMTISDNTATNMLISKLGGK +ELLNARFRSWGLVNTAIQSPLPDLEGT------NTTSPKELASLIAKVNQGELISMRSRD +LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR +PH-NEPAAAKLINSISQATYSY- +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Anabaenopsis circularis NIES-21 TaxID=1085406 RepID=A0A1Z4GE45_9CYAN +--QLRSQVQALAARYSLDAGMFFLDLDTGNYL-DLNGEKVFPAASTIKFPILVALFQEVD +AGRVKLNETLVMRRDLITGGSGEFQKRAGSRFSLIETVTKMITISDNTATNMVIDRLGGK +AKLNQRFRGWGLQNTVVRNLLGDFKGT------NTTSAKDLVRLSALVAKNQLLTDSSRS +KVLDIMQRVHN-TKLLPAGLGKGAVIAHKTGTLGI-VLGDAGIIQMPSGKRYLAGIFVRR +PFNDL-KARDFINQVSRIVYG-- +>[subseq from] Peptidoglycan glycosyltransferase n=2 Tax=Nostoc TaxID=1177 RepID=A0A2Z6CV00_9NOSO +--QLRSQVQALAARYSLDAGMFFLDLDTGNYL-DLNGEKVFPAASTIKFPILVALFQEVD +AGRVKLNETLVMRRDLITGGSGEFQKRAGSRFSLIETVTKMITISDNTATNMVIDRLGGK +AKLNQRFRGWGLQNTVVRNLLGDFKGT------NTTSAKDLVRLSALVAKNQLLTDSSRS +KVLDIMQRVHN-TKLLPAGLGKGAVIAHKTGTLGI-VLGDAGIIQMPSGKRYLAGIFVRR +PFNDL-KARDFINQVSRIVYG-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2E6RUG5_9SPHN +---LAREIAMLADGSNGRIGVYAVDLATGHEV-GVLADQRFPMASTSKVAIAAAYLAGVD +EGRWSLTSEFRLPR-------------PGGALPAYKHLSLMISKSCNDCTDALLAAVGGP +RAVNKWMRNAGIEGFELSRDIRTLIRAWSVDAKDSATPRAMGQLLAGIYQGKWLSNHSRR +FLLDAMEETTTGKRRMRSALPVSANLAHKTGTLSR-TASDIGIFHTPDGRAIAAAIYVTG +QSPSMA----------------- +>[subseq from] serine hydrolase n=1 Tax=Pleurocapsa sp. PCC 7319 TaxID=118161 RepID=UPI00034CE117 +---LKVELEKLAEQYQLEPEMFLVDLDTKGFV-SLQGNKAIASASTIKLPILVAFFQDLD +RGKIHLEEQLTLTEEIIGSGSGNMQQEPGTKFSALEVADKMITISDNTATNMLIQRLGGQ +EALNQRFMDMGLTATRLQNPLPDLEGT------NTTSPEDLGNLLVKIDSGELISLRSRD +RLLHIMNNVVR-DTLLPQGLESGAIIAHKTGDIKS-VLGDAGIIDMPNGKRYIASVLVKR +PDND-PQAKEFIQKASQTAYQYf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00045207F3 +------------------------------------------------------------ +------------NKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTHPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Leptolyngbya sp. NIES-2104 TaxID=1552121 RepID=A0A0P4UG00_9CYAN +---------TIAPQTQLTPGFMVVDADTHTYV-DVNASNPIPAASTIKFPILVAFFQAVD +EGKIRLDEPLTMRKELVATESGDLQTLPGSQFPAIEVATKMIDISDNTATNMIIDRLGGK +DALNQRFQSWGLTNTAIQNLLPDLPGT------NISSPRDMVALLDAVNRGELVSMRSHD +RMLNIMRKVAN-NSLIPQGLGEGSAIAHKTGDIGI-MLGDVGIIDLPNGKRYLMAAMVKR +PHND-DRAGDLIRQVSKLTYQYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas gei TaxID=1395960 RepID=A0A4S1XH02_9SPHN +-----ASIDTITRNFSGLAGIAVTSIDDGWMAsNVTARRPLPQQSVSKLWVTMTVLDAVD +RGTVRLDDPLTITRADFTLHQPIASLVKGDTTTVAEIMRRAMQMSDNTCNDKLLRLVGGP +QAVRDFIARKQLGTIRFGPGEKLLQASYVKDPPDGAAPASIAEALARLKRGELLSPSSTD +WLLATMGGAKTGKARVRGAVPPGWLYGHKTGTGQTAGFNDVGILTAPDGRSYALAVMIGD +TSRPIRERQLLMQAVARAVVAY- +>[subseq from] Cephalosporinase n=3 Tax=environmental samples TaxID=48479 RepID=X2KYL7_9BACT +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVFKFPLALTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRMTIRELLEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS +EISVMLEQCRTGLDRLALLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD +SNYDIATTSAIIAEVSKIVLE-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas naasensis TaxID=1344951 RepID=A0A4S1WHD7_9SPHN +--DLVAAIDTITRNFNGLVGVAVTSIDDGWMAsNVTATRPLPQQSVSKLWVSMTVLDAVD +RGVVRLDDPLTITRADFTLHQPVAALVKGDVTTVAEIMRRAMQMSDNTCNDKLLRLVGGP +AAVRDFIARKQLGSIRFGPGERLLQAAYVKSPPDGAAPASIADALARLHRGELLSASSTD +WLIATMAGAKTGKARVRGAVPPGWSYGHKTGTGQTAGFNDVGVLTAPDGRRYAIAVMIGD +TVRPIRERQLLMQAVASAVVAH- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora pattaloongensis TaxID=405436 RepID=A0A1H3G8C9_9ACTN +--ALTKRLREIVDAADNRAGVAVRDLSGRRDI-AVNGSFRPPAASVIKLWILAELLRQVD +CGRLSLEKKVLVERRDVVAGAGLRDEKLPQRVPVRRLAELMITVSDNTATNVLIDTLGGV +APVNALIRALGQQQTQLGSKLYDPS---PRARGNYTSAVDVVSLLAAVWEGRLLSPASRD +FMIDLMRGQTI-DTKIPAALPPDAPVAHKTGELED-AAHDVGYYLIPGS-EVAVAFLTAG +PE---APGTELVRELARAVYDH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5SGE9_9BACT +-kKLETRVEEIAARLDGVMGVAILDLTDGRIL-LRNADRVFPTASSIKIAILLELYRQDQ +KGKAKLNELYTFDPKDLVEDSQIMAGLTAGMVTNRDLAQFVVAVSDNAATNVLIDRV-GM +QNVNATLRNLGLTKTMLRRKMIDIAAARRG-DENVSTPQEMARLLEMIYKGKALNKELTD +QLIKQLKTLKK-DSYLSYELPTGVDIADKPGSLE-GVRNDSGIIFAQNR-PFAISVMTAY +DR-DEKAAERAISEVALEAYHYf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas jaspsi TaxID=392409 RepID=UPI0004B917AD +---LEQRLFSIANANPGNIGVAALDLKTGQLV-SVYGDDAFPMASTVKVAIAANYMSQVE +AGRRSLDATI-------------------GGQPVRSLMARMLIHSDNVATDMILNNLGGP +APVQAWIDQHGITGLRIDRTIASLLAAKRKDVRDSATPKAMVTMLQKLDSGAMLRPSSRD +YILDLMAQCATGKNRIPGLLS-GVKVQHKTGTLT-GLTTDVGYLTLPDGRRVAIAVFARY +GA----NRPATIATAARAVYDGf +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A2A4TZV8_9BACT +--KMGAELEKAAQAYPARVGIMVRDLGRGWTY-TYHADDLFPSASLIKVPIMVGVFDKIN +RGRLSLHSKLKLRRSTRMGGSGRIKWRRDGTFSVRQLLEMMMQRSDNTAMLLLIDEV-GM +GYLQNFFPTMGLVYTEIYPEGLRLTSG-RVRYENYTTPREMASIFEKGYHGELVNSFASE +LMMDIMKGKK-GKTRLAKKLPIGWEIAHKTGLLRR-SCHDVGVVYSPNGD-FVISVLTGR +NA-SYGQAKRFITKVGEITYRHy +>[subseq from] Putative beta-lactamase n=2 Tax=Erythrobacter litoralis TaxID=39960 RepID=Q2N9V7_ERYLH +--ALDQALFDIAAPFDGYLGIAVHDIARDRTV-HFNGNEHLPQQSLSKLWVTLAALRMVD +AGELDLSERVSIRRSDLTLHQPVRQIVLARGTTYGDLMRRAITESDNTANDMLLKRVGGP +AGVRNAIGEARLGAIRFGPGEVPMQSGYVLDPVDGATPRAIALALARLARGELLEPGTTA +LFLQLLKDVKSGPNRLKGGVPPGWSIGHKTGTGQQAGYNDVGILTAPDGARYSVVVMIGR +TAVPLPVRMELMHKVVEAIVRY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=M4QHL2_9BACT +--ETLVKVKDAEDQLGARVGYIELDLSSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0009901C54 +------------------------------------------------------------ +----------HINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Serratia fonticola TaxID=47917 RepID=U6A4F7_SERFO +--------------------------------------------------AVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLDGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTTWVVGD-------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5330 TaxID=2019670 RepID=A0A2N6MGF5_9CYAN +--QLNTQVKALMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD +AGRIKLNETLVMRRDLMTGGSGTLRKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFQSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS +KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] Uncharacterized protein n=1 Tax=Calothrix desertica PCC 7102 TaxID=232991 RepID=A0A433VGT7_9CYAN +---LETQIKTLMNRYSLTPGLFFLDLQTGDYL-NINGERIFPAASTIKYPVLIALFEEVD +AGRIRLDETMVMQRRHLAGGSGNMRFRSGTKFSLLETATRMMTISDNTATNMVIERLGGI +AKLNQRFRKWGLEQTAMRNMLGDFGGT------NRTSAKDLVRLSALVTNSNLLSDASRT +QVLNIMYRCQN-RRLLPSGLGKGANIAHKTGTLRF-VLGDAGIIQTPSGRKYLAGILVRR +PHHS-PQARDFIRQVSQLVYNY- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas endophytica TaxID=869719 RepID=A0A147I8C9_9SPHN +--ALQERVTQLIRSFPGKAGAAIQAVDEDWIV-SEGGALYLPQQSVSKLWVAMTVLAQRD +AGRLKLDDPVLVTRDDLTLHQPIASLVTAQGTTVGGLMTRALTQSDNTANDRLLTVVGGP +AAVRRFLAEKHISGIRFGPGERLLQSRYIDNPADGAQPAAIVEAMARLARGELLSETSTR +ILLDTMAASHTGRARLKAATPPGWKLAHKTGTGQNAGFNDIGLLTAPDGRRYAIAVQIGD +TTAPMRVRQVLIQQVAAAL---- +>[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A525JZD9_9CAUL +--ELQATLERIVQGYGEPVGIAVSDVTSGWTA-SVAGRETFPQQSVSKLWVALAVMQAVD +DHRLSLDQNVVMHAEDRSVYQPLASRIRGPNITLADLMRHALIESDNAANDMLIRQVGGA +GVVTQAIADKHLAGLAVGGTERDVQTNYLANPPDGATPDGITTALAALKRGELLSRASTD +FMLDLMGEARTGVMRLRAGVEPGWSLAHKTGTGPSVGINDVGLLTAPDGRTYAVAVMVRE +TKQPPSARHRLMIGVARAIEAYw +>[subseq from] Serine hydrolase n=1 Tax=Scytonema millei VB511283 TaxID=1245923 RepID=A0A1D2PFN1_9CYAN +--QLSSQLKTLIARYSLSPGMFFLDLDTGNYL-DFNGEKVFPAASTIKFPILVALFEEVD +AGRIKLNETLVLRRDLKAEGSGVLQYPVGTRLSVLDTATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALITNNKLLSDRSRS +QALGIMRRVEN-RRLLPAGLGKGAVIAHKTGTLGV-LLGDAGIIELPSGKRYLAGILVKR +PFGD-TRARVFISQVSKLVYG-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Aeromonas sp. C_PIA_I1 TaxID=682902 RepID=D1LFF0_9GAMM +------------------------------------------------------------ +-----LNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWAVGD-------------------------------- +----------------------- +>[subseq from] Uncharacterized protein n=2 Tax=Alistipes sp. An54 TaxID=1965645 RepID=A0A1Y3WV54_9BACT +--TLEQDLEQLAASLEARIGIAIR-TPDGETI--SRQDVPLPLLSVFKFPVALAVLDKAD +AEGTPLTTPVEVGPEWLDPYSPLRDSLPATGVTLGELLRYSTSLSDNIACDRLLEYVGGP +NAVERYVEKAGIEGFRIAATERTMHLDPANQRINVARPSAVCALFARLLEGGLLTPEHET +LLQRLLEGAVTGTDKLRAGLPEGAVLGHKTGSSDRTADNDAGYVVLPDGRHYCVTVLVTD +SPADDAKNAAVIAAISKRIYEHf +>[subseq from] Beta-lactamase n=1 Tax=Cyanothece sp. (strain PCC 7425 / ATCC 29141) TaxID=395961 RepID=B8HM72_CYAP4 +---LQQRLAGYRKTYPAQSGMFFLDMDNGNYV-DLNGDKIFPAASIIKLPILVAFFQAVD +AGKVRLDEKLTLRPELFASGSGEMQQRPWTQFSAQYTAAQMIIISDNTATNLILKRLGGP +GVLNQQFRSWGLKQTVIRNWLPDLSGT------NTTTARELVNLLTLLDQGKLLTPSSRE +KALAILRQTKN-RKLLAAGLGPGAVFAHKTGDIGF-MLGDAGMIQMPTGKRYMAAVIAKT +PY-DDPAGWTFMREISKIAYTYf +>[subseq from] Serine hydrolase n=1 Tax=Natronospirillum operossus TaxID=2562806 RepID=A0A4Z0WE30_9BACT +--RLESRLEVVDTEFSGDLSVYVAHTGSGESV-SLRGHEHWYLASTIKVPVAIELLAQVD +AGERSLDDQVALEGRDYVDGAGQTNWHDGTEFTLEHLLQEMLVVSDNAASDMVIRTV-GI +DNVNTRMEALGLDFVGPITSLADVRRAYYQTPYNSGTLSAMGQMMARLVEGELLSADSTD +YLLDLLQTIETGDNRLRATLPDDARFAHKTGTQHR-RACDIGAVLAENDRSAVVVAVCTR +GPRSTAEAERAMRAVGEAVTE-- +>[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5268 TaxID=2019662 RepID=A0A2N6KCD7_9CYAN +--QLNTQVKGLMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD +AGRIKLNETLVMRRDLMTGGSGTLRKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS +KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] serine hydrolase n=1 Tax=Calothrix sp. PCC 7103 TaxID=32057 RepID=UPI000303AF4A +---LETQIKTLMNRYSLTPGLFFLDLETGDYL-NINGEKIFPAASTIKYPVLIALFEEVD +AGRIRLDETMVMQRRHLAGGSGNMRFRPSGTFSLLETATRMMTISDNTATNMVIERLGGI +AKLNQRFRKWGLEQTAMRNMLGDFGGT------NRTSAKDLVRLSALVTNSNLLSDASRT +QVLNIMYQCKN-RRLLPSGLGKGANIAHKTGTLRF-VLGDAGIIQTPSGRKYLAGILVRR +PHHS-PQARDFIRQVSQLVYNY- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. QSSC1-22B TaxID=1860125 RepID=UPI00119E2CC4 +------------------------------------------------------------ +------------------------------GASAHYLMDRMMVRSDNRATDELIATLGGP +RAIDRWLRGHGLTGIRVDRNIADLLAARRWDVRDSSTPLAMLELLRLVDGNLALSAQSRA +TLIDMMRRCATGSNRIRGMMPYGAVVENKTGTLNS-YTTDVGFLTLPDGRRLAVAFFARG +GE----NRPAVIATAARAIYDGf +>[subseq from] serine hydrolase n=1 Tax=Calothrix desertica TaxID=32056 RepID=UPI000F8C7BD9 +---LETQIKTLMNRYSLTPGLFFLDLQTGDYL-NINGERIFPAASTIKYPVLIALFEEVD +AGRIRLDETMVMQRRHLAGGSGNMRFRSGTKFSLLETATRMMTISDNTATNMVIERLGGI +AKLNQRFRKWGLEQTAMRNMLGDFGGT------NRTSAKDLVRLSALVTNSNLLSDASRT +QVLNIMYRCQN-RRLLPSGLGKGANIAHKTGTLRF-VLGDAGIIQTPSGRKYLAGILVRR +PHHS-PQARDFIRQVSQLVYNY- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=unclassified Acinetobacter TaxID=196816 RepID=D1LFE2_9GAMM +------------------------------------------------------------ +-----LNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVG--------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas endophytica TaxID=869719 RepID=UPI000737052D +--ALQERVTQLIRSFPGKAGAAIQAVDEDWIV-SEGGALYLPQQSVSKLWVAMTVLAQRD +AGRLKLDDPVLVTRDDLTLHQPIASLVTAQGTTVGGLMTRALTQSDNTANDRLLTVVGGP +AAVRRFLAEKHISGIRFGPGERLLQSRYIDNPADGAQPAAIVEAMARLARGELLSETSTR +ILLDTMAASHTGRARLKAATPPGWKLAHKTGTGQNAGFNDIGLLTAPDGRRYAIAVQIGD +TTAPMRVRQVLIQQVAAAL---- +>[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus sinduriensis BLB-1 = JCM 15800 TaxID=1384057 RepID=A0A0A3HVR8_9BACI +----EKAILRLLEQAPFDIRLIIKDAGGSQFLlSKNPDDVFQSASLIKVPILLALLDSIE +NRNFTLHQTVQISKENRVEYSVLTEL-GTEECSLHDLLVWMIITSDNTATNVLIDLI-GL +ENINRYFKKVGLTQTKIQRKMMDFHQM-ARGFDNVTTAADMATLYTAIYRKSLLSKEHSE +LVIDILSRQRV-HESLRRYLVEDVKMAHKTGSLAT-VEHDVGIVFSSKRD-YIIGVFVTD +HTNS-EEAKRFIGQVSKIVYDH- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI00068952B7 +---LQENLEKIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVQ +MGKVELKERIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK +ESVNQYMKEIGLSNTYIRLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH +DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGNFIISVFSIG +NN-TEAEGASIISKLSRVAYNHf +>[subseq from] Peptidase_S11 domain-containing protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A353ZAM2_9PLAN +-qTLDRRLKGLIEDHDGEVAVAVEHLQTQERF-GFRSDEVMSAASLIKFPVMVEVYRQSE +QGQIELHQFLELTEQDKVPGSGILTPHFSPGLAIVDAVRLMIAFSDNTATNLLLDKI-GL +GATTETMRTLGFPNTRLNSKVYRRETRSREFGLASTTADEMVGLLRLLHERKLVSPKASD +AMHAHLLNCDD-HHKFPRFLPEGAKVAFKTGSTE-AIRSAAGILETPRG-PVAICVLTSE +NASEDNEGDVLCARIAREVWDYf +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Aminicenantes bacterium TaxID=2052149 RepID=A0A2N7Q988_9BACT +------NILKRISTFRGEAGITVKDLKTGWTF-LHNEDQPFPAASLVKIPVMVACFKAAQ +DGLIDLEAGYVLQRKDKTGGSGLLRRMRSGRFTFRELVDYMVTESDNTAANILIDKL-GF +DYINRVFREIGLKKTVLNRKMIDFNAR-DQGMENYTTAAEITSLLEKIYYGQCFNQEISQ +KCLEVLKRQKI-NDRLPRYLPKGVIVAHKTGLEKE-VCHDAGIVFTPYGD-YIITVLVHT +WGGP-TTAKNFIARLSSYFYQVf +>[subseq from] Serine hydrolase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A519J306_9CAUL +------ALVAHAAQADGVLGACIVD-RHGAAC--ANGDRPISMQSVMKLLVGMAVLDAVD +QGRLTLDDEVLLTRDDVSVFVQPLEKLIGPDTTVGELIRGAITESDSLATDWLIDRLGGT +AAVQAYLDRKGIVGVRLDRDERRLQTAYQNDVRDTATPRGLATLLYRLGDGQLLSAGSTR +WILDVMGETGTFPDRLRAGTPADWWIGHKTGSSSVGVTNDVGVMRAPDGAVIGVVALLAN +SSAPAPERAAAIAGVSRIAAET- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2D8TCP7_9SPHN +-----SVIRNLGQSFRGKVGIAVRRVGADWTV-AWNGTALFPQQSVSKLWVSMTFLDAVD +RGKLRLTDTTTITRNDLTLHQPSAALGARDGTSYSDLMRRAMTQSDNTCNDALLRAAGGP +DAVRGFLARRMIKDIRFGPGERLLQSNYLANPPDGAAPSSIVAALAKLKQGDMLSPASTR +LLLNVMSEAKTGPQRVKGGVPAGWHYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS +TTVPIPERWALMQGVAKAVAA-- +>[subseq from] serine hydrolase n=1 Tax=Negadavirga sp. SW125 TaxID=2164132 RepID=UPI000E0A8D1D +-eELKSKLEERVTQVDGTIAVALKVLEGGKETlFIHEREVFHAASTMKTPVMMEIYRQAE +QGKFSLSDSIPVVNESIVDGSPFSYHMIGQKETIYELMYQMIIKSSNLATNILIDLI-GA +SNVNEFMREIGANDIQVLRGVEDLKA-FEAGLNNTTTALDMMLIMEAIATGKAVNQEASL +QMMDILYDQYY-KDLIPKKLPEEVKVAHKTGSIT-GVQHDAAILELPDGKRYVLVILSKE +LK-DVEEGKEAIADISRQIYQY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella aquatilis TaxID=34038 RepID=U6A4U0_RAHAQ +-------------------------------------------------MAASAILKESE +VKKNLLTQHVVLKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP +NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWIVGD-------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. QSSC1-22B TaxID=1860125 RepID=A0A1A7QLY0_9SPHN +------------------------------------------------------------ +------------------------------GASAHYLMDRMMVRSDNRATDELIATLGGP +RAIDRWLRGHGLTGIRVDRNIADLLAARRWDVRDSSTPLAMLELLRLVDGNLALSAQSRA +TLIDMMRRCATGSNRIRGMMPYGAVVENKTGTLNS-YTTDVGFLTLPDGRRLAVAFFARG +GE----NRPAVIATAARAIYDGf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas ginsenosidivorax TaxID=862135 RepID=A0A5C6UJM8_9SPHN +--DLLNAVQALGARFQGAAGISVRDIDEGWVV-AWEGDTPRPQESVSKLWVAIAVMDAVD +RGRLSLADPVTVTRSDLTVHQPIRTLVGADGTTIGELLRGAMTRSDNTCNDVLLWRVGGP +AAINRMLADKGIAGVTFGPGERQLQARYLADPIDGASANGVTLGLSLLAQGKLLGARSTA +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS +TRQPIPVRMRLMGDVTRAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. ZYM-1 TaxID=1681184 RepID=A0A0N8IKA0_9BACI +---LQERLEEIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVE +VGRVELKERIRLKEEDFVNGSGIFKELIPGVVTIKNLATMMIIVSDNVGTDKLLNIL-GK +ENVNLFMKEIGLCNTYIHFSCWELLCFQESHENNVTTAADMAALLEKIANKQLISDKACE +DMFEILAKQQF-RHRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGNFIISVFSIG +NK-TEAEGASIISKLSRVTYHHf +>[subseq from] Beta-lactamase class A n=1 Tax=Stakelama pacifica TaxID=517720 RepID=A0A4R6FWF8_9SPHN +--ALTAIIQSAVRNFDGKAGVAVESVDDGWIV-SANGETLMPQQSVSKTWVAMTVLAQRD +EGRLSLDDPLTITTADLTLHQPIAALVQKNGSTVGEIMKRALTMSDNTCNDKLLWLVGGP +PAVRAFIESRKLGAIRFGPGERLLQSAYIADPPDGAAPVAIADALARLKRGELLSAGSTS +WLITTMQSSHTGRNRLRGEVPGDWLFGHKTGTGQTAGYNDVGILTAPDGRSYTVAVMIGD +TARTIPQRWELMHTVVKAIVN-- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter vulgaris TaxID=291985 RepID=UPI0005961D5D +-sQLEKTVASLADGSRGRIGVYAIDLTTGQEI-GVLEDQRFPMASTSKVAVAAAYLAGVD +AGKWSLTSEWRLPR------------RGGAYLTGLEHLNLMISKSCNACTDALLEAVGGP +AAVNKWMRDAGIEDFQLTRDIATLVRASSVDLRDSASPRAMGQLLAGIYQGRWLSTSSRA +VLMDAMRATTTGKKRMRSALPTSAGLANKTGTLSR-TASDIGIFHTPDGRAIAAAIYVTG +QSPSMAVE--------------- +>[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. (strain YBL2) TaxID=484429 RepID=UPI000A059ED2 +--DLLNAVEGLGQSFKGEVGISVRDLDEGWTV-SFNAERMLPQQSVSKLWVAIAVMDAVD +RGTLSLSDPVMVKKSDLTVHQPIRSLVTKAGTTIGKLLELAMTRSANSCNDVLLWKVGGP +QAIRAMLKRKGLDDVGFGPGERKLQARYLADPYDGASANGVTFGLMRLKQGKLLSGRSTR +HLLGLMRASRTGPQRLRSGLRKGWTLAHKTGTGQATGYNDVGILVSPDGNRYAVAVMIAS +TRLPIPARMRLMGNVTRAIVR-- +>[subseq from] serine hydrolase n=1 Tax=Phenylobacterium deserti TaxID=1914756 RepID=UPI00140335D4 +--ELQARLTELAEDYREDVGIAVTDVTERWTA-SVDGGSLYPQQSVVKIWVALAMMEAID +QGRFRLDQPVLVRPEDRSVYEPLGRKIGRTGTTYYDLLSRSLTESDNTANDKIMSEVGGA +AIVTDVVARKGLTGIGIGGDEKMLQSAYLANPPDGATPIGLTHGLAALQRGELLSKPSTD +TLIGLMAEAKTGNLRLKAGLPPGWSIAHKTGTGPSVGINDVGLITAPDGRVYAVAVMLRE +TKRPFRDRQRLMQQVARAVADHw +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V577_9BACT +------------------------------------------------VMAAAAVLKQSE +TQKDLLSQRVEIKSSDSINYNPIAEKHVNGTMTLGELSAAALQYSDNTAMNKLIAHLGGP +GKVTAFARAIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA +QLVMWLKGNTTGAASIQAGLPTSWVV---------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. TDK1 TaxID=453247 RepID=UPI0009FE097F +--ALLNAVQALGAGFQGQVAISVRDVDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID +HQRLSLATPVTVTRADLTVHQPIRPLVGSSGTTVGALLECALTRSDNTCNDVLLWKVGGP +AAIRRMLKEKGIDGVGFGPGERELQARYLAAPYDGATANGVTLGLSLLAQGKLLSHGSTD +RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPDGHRYAVAVMIAS +TRQSIPVRMRLMGDVTRAVIR-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A645AR96_9ZZZZ +--ELKNNIENIISNSNGNIAVALRMMNDKSTI-MINENMIFPSASTIKLVIMSTLMREVK +EGRMSLNDRIKLLNCSKCGGDGILKELEEGHFTLKEIITLMIILSDNTATNILIDML-GM +KKVNEEAERLKLYNTQLRRKMMDSVAA-KMGRENVTTAKDLCSILESIYERKLVSEEYSE +IMLDILKRQQV-GGRLNLYLPEDLVIAHKTGDLDK-LEHDVGIVFHPKD-NYIICVLTKK +VD-TNKEGKEIIGKISHEVYK-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas taxi TaxID=1549858 RepID=A0A2W5PH40_9SPHN +--ALQERVSQLIRAFPGKAGAAIQAVDEDWIV-SQGGTLYLPQQSVSKLWVAMTVLAQRD +AGRLKLDDPVLVTRDDLTLHQPIAGLVTADGTTVGSLLTRALTQSDNTANDRLLTVVGGP +AAVRRFIADKRLGAIRFGPGERLLQSRYIDNPPDGAQPVAIVDALARLARGELLSETSTR +VLLDTMAASRTGHARLRAATPPGWKLSHKTGTGQNAGFNDIGLLTAPDGRRYAIAVQIGD +TTAPMRARQVLIQQVAAAL---- +>[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium deserti TaxID=1914756 RepID=A0A328ATW1_9CAUL +--ELQARLTELAEDYREDVGIAVTDVTERWTA-SVDGGSLYPQQSVVKIWVALAMMEAID +QGRFRLDQPVLVRPEDRSVYEPLGRKIGRTGTTYYDLLSRSLTESDNTANDKIMSEVGGA +AIVTDVVARKGLTGIGIGGDEKMLQSAYLANPPDGATPIGLTHGLAALQRGELLSKPSTD +TLIGLMAEAKTGNLRLKAGLPPGWSIAHKTGTGPSVGINDVGLITAPDGRVYAVAVMLRE +TKRPFRDRQRLMQQVARAVADHw +>[subseq from] class A beta-lactamase n=2 Tax=Coxiella burnetii TaxID=777 RepID=UPI0000DAEA03 +------------------------------------------------------------ +------------KKNELVSYSPITKNHINGGITVSELCAAALTLSDNSAANLLIKKLGGL +TAINAFARSIGDKQFELDRLEPQLNSAIPGDIRDTTTPEAMANSLKRLTLGDILAFP--- +QLTTNMVKKIILQEMPKSELAFRKTVGDKTGSGGYGTTNDIGIIWPPKRAPIVVAIFFKK +NKKGAVSPDSIIERITRILM--- +>[subseq from] Serine hydrolase n=1 Tax=Leptolyngbya sp. TaxID=47254 RepID=A0A2W6ZXN8_9CYAN +------GLQSLIQQNKFKPGVFLVDLDSNDYL-DLSGAASFSAASMIKLPILIAFFQDLD +SGKIQLDEKLVMRQEVVADGSGDLQYLPGSQFTALDTVTRMITISDNTATNMLVARLGGM +SSLNQRFKSWGLSTTTLNKPLPDLQGT------NTSSPKELASLMVRVSQGDLVSLRSRD +RMLDIMRRTIN-NSQLPQGLGEGATIAHKTGDIGT-LVGDVGLIDMPNGKRYATAVFIKR +SFND-DAAYDLVQKISRLIYQH- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001249007B +------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Sphaerobacter TaxID=2056 RepID=D1C1J1_SPHTD +---TIERIRALAEDFAGTIGVAARDLDTGTEV-MYNPDVVVPTASTMKTVLLYELYRQVD +AGQIDPAMRITLEERHRVPGSGVLQDLDAGVPTVKDVATLMITVSDNTATDMIYDLI-GR +EAVATTLERLGMTNTHLPLDTWEILALRETPDNDVSTPRDMLRLVEAIFRGEGLSPASRE +AVIDILKRQKY-TTIIPEQLPFGVKAAHKTGTLR-GVRNDVGLVFAGER-TYAVALMSKG +SP-NLVASQRLLSDISRLIYECf +>[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides sp. An51A TaxID=1965640 RepID=A0A1Y3WYF1_9BACE +---LQEQIQQITANTDAHVGVALI-IDGKDTI-TINNDDRYPLMSVMKYHQALAVAHYLD +KHHLPLSTSVFIRKEDLRPYSPLRDRYPEGNLPISKLLTYTLQLSDNNACDILFDYIGGT +EETDKYLRTIGCDQFAVTATEDDMHKNLALCYNNWSTPLSTARLMDRLAAETLIDTSYTH +FIRETLLDCQTGKARLPFPLQTETRIGHKTGTSDQNGINDAGFILLPNGKRYTLVVFVKH +SKLSFEATERVIADISAVVFR-- +>[subseq from] Beta-lactamase (Fragment) n=4 Tax=Rahnella TaxID=34037 RepID=U6A718_RAHAQ +-------------------------------------------------MAASAILKESE +VKKNLLTQHVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP +HKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWIVGD-------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium sp. HMP27 TaxID=1487921 RepID=A0A099SCY6_9CLOT +--ELKNNIENIISNSNGNIAVALRMMNDKSTI-MINENMIFPSASTIKLVIMSTLMREVK +EGRMSLNDRIKLLNCSKCGGDGILKELEEGHFTLKEIITLMIILSDNTATNILIDML-GM +KKVNEEAERLKLYNTQLRRKMMDSVAA-KMGRENVTTAKDLCSILESIYERKLVSEEYSE +IMLDILKRQQV-GGRLNLYLPEDLVIAHKTGDLDK-LEHDVGIVFHPKD-NYIICVLTKK +VD-TNKEGREIIGKISHEVYK-- +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium Pla123a TaxID=2528002 RepID=A0A5C5YTU3_9BACT +---FNSSLVDLLESHRGTVSAAAKHLPSGEEF-SFQADRPMPTASLIKLPILATAYHAAA +EGKVDLDAMVTLKEEDKVPGSGVLTANFSAGMPLHDAIRLMIAFSDNTATNLVIDQI-GL +PATNEYMDQLGLNNTRLHAKVFRRDTSIAPERSGSTSASEMLKLLEQIERGELISKQASK +SIYEHLLACES-RSKVPRYLPEETRVAHKTGSVS-AVRCDAGIIESPKG-PIAFCILTGD +NEGDENEAELLAAEFGKAIYAHw +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. CCP-7 TaxID=1979270 RepID=A0A437LYL1_9SPHN +--ALDRRIEALGAAFRGDVGLAVRDIQTGWTS-HYRGLDYFPQQSVSKLWVAISAFDMAD +RGKIDLHGKLSIRADDLTLHQPIKSLATRPGTDREDLLTRALTQSDNSANDKMLREVGGP +DAVRATLAAKSISGIRFGPGEKGLQSAYVADPIDGARPLAMVDALARLKNGQLLSDASTA +QMLDIMGQTRTGALRLKSGLRPGWTLSHKTGTGQQAGYNDVGILTSPEGRSYAIAVMIGR +TSRPLPERMDLMRKVVRTTIT-- +>[subseq from] serine hydrolase n=1 Tax=Aphanizomenon flos-aquae TaxID=1176 RepID=UPI000488404E +--ELQTPIKTLMARYKLSPGIFFMDLNTGDYL-SINGDKSFAAASTIKYPILVALFQQVD +AGKIQLDETLVMGKKHIVGGSGNMQYRLGSKFSLLETATRMMTISDNTATNMIIDRLGGI +TQLNQKFRSWGLQNTVMRNRLGDFQGT------NKTSAKDLVKLSALMENNQLLSNISQL +QVIGIMNGCHN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETPSGKRYLAGVFVQR +PNND-PRGTDFIRQVSQVVYGYf +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6GD88_9BACT +-kKLETRVEEIAGRLDGVMGVAILDLTDGRIL-LRNADRVFPTASSIKIAILLELYRQDQ +KGKAKLNELYTFDPKDLVEDSQIMAGLTAGMVTNRDLAQFVVAVSDNAATNVLIDRV-GM +QNVNATLRNLGLTKTMLRRKMIDIAAARRG-DENVSTPQEMARLLEMIYKGKALNKELTD +QLIKQLKTLKK-DSYLSYELPTGVDIADKPGSLE-GVRNDSGIIFAQNR-PFAISVMTAY +DR-DEKAAERAISEVALEAYHYf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0009907C70 +------------------------------------------------------------ +------------NKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase class A n=1 Tax=Parafilimonas terrae TaxID=1465490 RepID=A0A1I5WC18_9BACT +--QLKDKIAAQIEKHKGRYAVAFKNLSNGEEI-LINEHENFHAASTMKTPVMIEVFKQVQ +AGNFSMNDSITLKNESIVDESSFSYKHIGENRSVYQLMYNMIIMSSNFATNLIIDLV-GA +ENANETMREMGAKDIQVLRGVEDD-KAYEKGMNNTTTAYDLMLIFSKIANGEIVSKPACD +SMIDILSNQHF-NSVIPAKLPKDVKVAHKTGSIIS-VQHDSGIVFLPDGKKYVLVLLSKD +WT-DEKDAIGLMADISKTIYDH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudochrobactrum sp. C_SS_V3 TaxID=683080 RepID=D1LFE0_9RHIZ +------------------------------------------------------------ +-----LNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVG--------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Calothrix sp. HK-06 TaxID=1137096 RepID=A0A1Q4REK9_9CYAN +--QLSSQVRSLMSRYSLDPGLFFIDLETGNYV-DYNGEKAFSAASTIKFPILIALFQEID +AGRVKLNETLTMRRDLVTGGSGTMQYRAPGTFSLLETATRMITISDNTATNMIIDRLGGK +NKLNPRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALVANNQLLSNSSRT +RALDIMRRVEN-TSLLASGLGRGATIAHKTGTLGV-ILGDAGIIQMPNGKRYLAGIFVRR +PFGD-RRGTEFISQVSRTVYS-- +>[subseq from] class A beta-lactamase n=1 Tax=Alistipes megaguti TaxID=2364787 RepID=UPI0013CF3A27 +--TLEQDLEQLAASLEARIGIAIR-TPDGETI--SRQDVPLPLLSVFKFPVALAVLDKAD +AEGTPLTTPVEVGPEWLDPYSPLRDSLPATGVTLGELLRYSTSLSDNIACDRLLEYVGGP +NAVERYVEKAGIEGFRIAATERTMHLDPANQRINVARPSAVCALFARLLEGGLLTPEHET +LLQRLLEGAITGTDKLRAGLPEGAVLGHKTGSSDRTADNDAGYVVLPDGRHYCVTVLVTD +SPADDAKNAAVIAAISKRIYEHf +>[subseq from] serine hydrolase n=1 Tax=Clostridiales bacterium mt7 TaxID=1631345 RepID=UPI000C75BB79 +--NLQESIERVVAQQQGTFGVYVKHLITMESA-SVNGDRLFQTASVFKVPILATLMRDVV +EGRSDLNQRVRLTSEDIVPGSGIFKELEPGVVTIKDLATMMIIVSDNLATDQVLSIV-GK +ERVQEYMSELGLSKTFIRFNCWELLSYQETSENNVSTPVEMGILLEHIVTKKVISEEASA +KIFDIMTKQQL-RNRIPRLLPKGTLVGCKSGTLGS-VVNDCGIVQLPDKKGLFVIAVFSK +DNPTIPQGEEVIAKLALTAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. RIT328 TaxID=1470591 RepID=A0A031HN48_9SPHN +------------------------------------------------------------ +-------------------------------RSAAQLMELMIVRSDNHAADQLLAAVGGP +VAVQQWLATNGIAGIRVDRTIAQLLRE-PGDSKDVATPNAMVALLDKL-NGPLLSAESRG +LLFGLMSRCATGTRRIRALLPAGTRVEDKTGTLD-GVTNDVGFITMPDGRRLAVAVFARG +GR----DRQPGIAAVARAIYDRf +>[subseq from] Serine hydrolase n=1 Tax=Muribaculaceae bacterium Isolate-114 (HZI) TaxID=2486475 RepID=A0A3N2NHE2_9BACT +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVIKFPLALTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRMTVRELLEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS +EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSVAVFVAD +SNYDIATTSAIIAEVSKIVLE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Caulobacteraceae bacterium TaxID=1978230 RepID=A0A4Q3S3R2_9CAUL +-eTLQRRLNALALQFPGDVGIAVRRLGAGWTV-SVNGDRPMPQQSVSKLWVSMAILAAAD +RGELSLDETVLIRKQDLSIHQPIRRYVGEAGASLRSLMAGALQQSDNAANDALVRRLGGP +FAVQVAIVGRNLDGIRYGPGERAMQTAYLANPPDAATPLGLVEALSRLHGGELLSPGSTA +LMLQEMGGSLTGGGRLRAGLPTGWRLAHKTGTGQATGYNDIGLITAPDGRVYAVAAMIAA +TRRPLPERQRFMVGVARAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Trichodesmium erythraeum (strain IMS101) TaxID=203124 RepID=Q10XW0_TRIEI +--ALKTELDTIITKFSLTPGVFLIDTDTGAYV-DINGDATMAAASTIKLPILVAFFQAVD +QGRIKLNDLLTMKESHVAEGSGNMQRNPGSKYTALQTVRKMIIISDNTATNMLIEELGGA +EILNQSFQSWGLKNTVINNSLPDLSGT------NTTTSKDLINLISQINQGGLVSLKSRD +RLFRIMERTQN-NSLLPRGVGRGSVVAHKTGNLKS-MLADVGMIDLVNGRRYLLAVLVKR +PDED-QDAVDLIRRVSKETYKY- +>[subseq from] Beta-lactamase class A n=1 Tax=Chamaesiphon minutus (strain ATCC 27169 / PCC 6605) TaxID=1173020 RepID=K9UAP8_CHAP6 +---LKSQIKALAAKYSISPGMFFMEVETGNYL-DINGEKSFPAASTIKLPILMALFQAVD +AGKIKLDEKLTVRRDLITGGSGRLQNSRGAKLSVLQTATKMIVISDNTATNMIIDRLGGR +KALNSKFKSWGLRKTVLNRMLGDFKGT------NTTSPADLVRLSALLAKRQLITETSRS +KVLDILNQTAN-RKLLPAGLGKGAAIAHKTGTLGR-LIGDAGIIEMPNGKLYLAGIFVKR +SFND-VRARDFVQAVSKLTYNY- +>[subseq from] Serine hydrolase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A520JET2_SPHSX +---LAANVTQLVRGFTGKVGVAVRSVDDGWLI-DAGGSQRLPQQSVSKLWVAMTVLSARD +AGKLRLDDPITLTRDDITLHQPIAGLIRGDTTTVGELLQRALTMSDNTANDRLMRLVGGP +NAVRGFIARKGLGAIGFGPGERMLQARYVANPPDGAAPTAITGALARLKRGDLLSAASTS +YLIGTMQSSHTGKMRLRGAVPAGWSFGHKTGTGQTAGYNDVGLLIAPDGRTYAIAVMIGD +TLRPIPARQQLMQAVVSSVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas taxi TaxID=1549858 RepID=A0A2W4YW50_9SPHN +--DLLNAVQALGAGFKGQVGISVRDIDEGWVV-AWDGDRPRPQQSVSKLWVAITVMDAVD +RGRLSLTDPVTVTRADLTLHQPIRALVGKDGATIGELLRGAMTRSDNTCNDVLLWRVGGP +VAVNRMLADKGVSGVKFGPGERQLQARYLAAPIDGASANGITLGLSLLSQGKLLSARSTA +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPNGHRYAVAVMIAS +TRQAIPVRMRLMGDVTRAIVA-- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001243A1F1 +------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00115502D6 +------------------------------------------------------------ +------------NKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Scytonema sp. NIES-4073 TaxID=2005464 RepID=A0A1Z4PRX2_9CYAN +--QLNSQLKTLLARYSLSPGMFFLDLDTGNYL-DFNGEKIFPAASTIKFPILVALFEEVD +AGRIKLNETLVLRRDLKAEGSGVLQYPVGTRLSVLDTVTKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALITNNKLLSDRSRS +QALGIMRRVEN-RRLLPAGLGKGAVIAHKTGTLGV-LLGDAGIIELPSGKRYLAGILVKR +PFGD-TRARVFISQVSKLVYG-- +>[subseq from] Uncharacterized protein n=1 Tax=Synechococcus lividus PCC 6715 TaxID=1917166 RepID=A0A2D2Q424_SYNLI +--------------------MYFFNLDSGAAL-NVGGDDVFPAASTIKIPILVAFFKAVD +ENRISLSERLTMRPDLIAPEAGTLQQKPNSQYPALEVADLMITISDNTATNMLIDRLGGA +AVLNQQFQEWGLKNTVINNLLPDMEGT------NTTSPRDLATLMLKIGQGELVSPRSRD +RLLDIMRRTVT-NTLLPAGIGPGATIAHKTGDIGT-VVGDAGMVDMPNGQRYVAAMMVKR +PYND------------------- +>[subseq from] serine hydrolase n=1 Tax=Anabaena sp. PCC 7108 TaxID=163908 RepID=UPI000364E537 +--ELQTPIKALMARYRLTPGIFFMDLQTGNYL-NINGDQPFSAASTIKYPILIALFQEVD +AGRINLNETLVMQRKHVTGGSGDMQRRVGTKLSLLETVNKMMTISDNTATNMMIDRLGGK +ANLNQRFRAWGLQSTVIKNMLGDFKGT------NKTSAKDLVRLSALITNNQLISDTSRS +QVLGIMIHCHN-RSLLPSGLGNGASIAHKTGTLRF-VLGDAGIIETPSGKRYLAGIFVRR +PNND-SRAIAFIRQVSQVVYGYf +>[subseq from] Serine hydrolase n=1 Tax=Cyanobacterium sp. IPPAS B-1200 TaxID=1562720 RepID=A0A1E5QSN2_9CHRO +-----------EKYANLQPSLFFVDLDNGAFV-NMNGMEAFPAASTIKTPILVAFFQDVD +EGKILLDEKLTMTEETKATEAGTMQYQPGTQYTALKVAEEMIIRSDNTATNMLIERLGGV +EALNQRFKEWGLESTVINNYLPDLEGT------NTISARDLAMTLVKVSNGNLVGTRSRD +RLLGIMQRTIT-RTLLPQGIEPDAMIYHKTGDIGK-VLGDGGIIDIPTGKRYVGAVLVQR +PHND-YTARTMIQEISREAYQHf +>[subseq from] serine hydrolase n=1 Tax=Bacillus niameyensis TaxID=1522308 RepID=UPI000781F890 +--RLITNIQNAVEQVGGTWGIALKDLDTQETW-DLNGDELFYAASVIKVPIMAAVFNAFD +KGEFTLSDTIILKREDLVGGAGILQFMTPGAFTIHDIMTLMIIQSDNTATNMLIDLV-GI +ANIQKTMKDIGLKRSSFYNKLMTVPVH--IDGKNLITAGEMATLLEKIACGKVVSVYACE +QMIDIMKKQQI-RDCLPGKLPPEWELANKTGWVS-GCRHDIGIFYVGKRK-MICAVLSKD +VD--DGKSLQVLAEIGKLIYDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. URHD0007 TaxID=1298856 RepID=A0A2U1G0L6_9SPHN +--DLHRQLIGLGRAFDGKAGIAVVSLRDGWEI-DWNANSLFPQQSCSKLWVAITTMDAVD +RGKVRLDSSVTLGRSDLTLHQPLREKILGGGTTLGSLLFDAITESDNTANDKLMRAVGGP +QAVRGMIARKGLGAIRFYNGERALQSRYISDPYDGASPHAIAGALAALKKGQLLSPASSS +RLLSIMGRTRTGGMRVRAALAPGWEWNHKTGTGQIAGLNDIGLLSAPDGSVYAMAIMVIA +NHS-DGSAQELMRDVTKAVIA-- +>[subseq from] serine hydrolase n=1 Tax=Spirosoma terrae TaxID=1968276 RepID=UPI0013D67B93 +--HLRKQVNQELAKQPGVFAVAFKDLGTGQEL-LIREREEFHAASTMKTPVMIEIYKQAA +QKRLSLDDSITIKTESIVDGSPYTYKYVGTKRTIDSLVYDMIIWSSNLATNLVIELA-DA +QKVTQTMREMGANDIQVRRGVEDSKA-FAQGLNNTTTAYDLMVIFEKIALGKAVSPAASE +AMIKTLLDQRF-KTKIPAKLPKDVKVAHKTGSIK-GVLHDSGIVFLPDGRKYVLVLLSKD +IQ-NEQAVENVMATVSKLIYDY- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas aurantiaca TaxID=185949 RepID=UPI000D38E32F +-----NAVQALGISFKGDVGISVRDIDEGWVV-AWEGNNPRPQQSVSKFWVAIAVMDAVD +RGRLSLTDPVTVTRSDLTVHQPIRAFVGKDGTTIGDLLRGAMTRSDNTCNDVLLWRIGGP +AAINRMLDEKGIAGVGFGPGERQLQARYLSDPLDGASANGVTLGLSLLAQGKLLSAQSTT +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS +TRQPIPVRMRLMGNVTRAIVA-- +>[subseq from] Metallo-hydrolase family protein n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520JEA4_SPHSX +--DLLNAVQALGAAFQGAAGISVRDIDEGWVV-SWEGDDPRPQQSVSKLWVAIAVMDAVD +RGQLSLADPVTVTRSDLTLHQPIRALIGKDGTTIGELLRGAMTRSDNTCNDVLLWRVGGP +AAINRMLADKRVAGVKFGPGERQLQARYLAAPMDGASANGITLGLSLLAQGKLLSARSTA +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPNGHRYAVAVMIAS +TRQPIPVRMRLMGDVTRAVVA-- +>[subseq from] Class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A5C8XA77_STAAU +------------------------------------------------------------ +------------NKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. JS21-1 TaxID=1855283 RepID=UPI000B879046 +--RLVNAVQALGRGFKGAVGISVRNIDEGWVV-AWEGDRARPQQSVSKLWVAIAVMDAVE +HGRLSLADRVTVRRSDLTLHQPIRALVGKNGTTIGALLRGAMTRSDNTCNDVLLWKVGGP +SAINRMLREKGIDGVKFGPGERKLQARYLAAPMDGASANGVTLGLSLLAEGKLLTPRSTA +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS +THQPIPTRMRLMGNVTRAIVA-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8WUY7_9BACT +-qKLEATINDVDHNLDGVLAAAIMDLSTGQKY-LFHADEVLPTASSIKIAILAELYRQAQ +QGKVKLTDLYILQQSDLVGGSGIAEALTPGTLTIRDVAALMISVSDNSATNIIIDRV-GM +ENVNALLDSLGLTHMRLRRKMMDLKAAG-EGRENVASPREFMLLLEALYRGRVLNKQFTE +DFFKLLSVHKE--SYIPRELPEDLRVANKPGELE-GVRNDSGIVFTGSR-PFVISVMTTY +LRRE-RDGGDAIVRISTAAYRMf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F1DI13_KLEPN +------------------------------------------------------------ +---------------------PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLDNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAKATTLRKVLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAA----------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Hydrocoleum sp. CS-953 TaxID=1671698 RepID=A0A261KN50_9CYAN +--ALKTELDTVIAKYKLTPGVFMIDADTGAYL-DINGDTAVAAASTIKLPILVAFFQAVD +QGRIKLNDMLTMEESHVAEGSGDMQRKPGSKYTALQTARKMIVISDNTATNILIEALGGA +DVLNQLFQSWGLKNTVINNPLPDLSGT------NTTTPKDLINLISQVNQGGLVSLKSRD +RLFRIMERTRN-DSLLPRGVGRGSVVAHKTGNLKS-VLGDVGMIDLLNGKRYLLAVLVKR +PD-DDQDAVDLIRGVSKETYQY- +>[subseq from] Beta-lactamase class A n=1 Tax=Atelocyanobacterium thalassa (isolate ALOHA) TaxID=1453429 RepID=D3ER03_ATETH +---LKKQLESINTKYNVEPKAWFLDLDSNTYV-NFNGTKSIAAASTIKIPILVAFFEKVD +AGDISLDQMITMDKEIIVGGSGNMQYMETGKFTALEIARKMIIISDNTATELLIRQIGGK +LFLNERFKKWGMRQTVINNSLPDLDGT------NRTSPEDLAKLLLKIEKGNLISLRSRD +RFLNIMRETKT-KTLLPKGLERNASIAHKTGDIGT-IIADAGIIDMPTGRRYIGAIFVER +DY-DDPAGRELIQNFSKTIYQYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TDK1 TaxID=453247 RepID=A0A196NEW7_9SPHN +--ALLNAVQALGAGFQGQVAISVRDVDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID +HQRLSLATPVTVTRADLTVHQPIRPLVGSSGTTVGALLECALTRSDNTCNDVLLWKVGGP +AAIRRMLKEKGIDGVGFGPGERELQARYLAAPYDGATANGVTLGLSLLAQGKLLSHGSTD +RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPDGHRYAVAVMIAS +TRQSIPVRMRLMGDVTRAVIR-- +>[subseq from] Beta-lactamase class A BlaZ n=1 Tax=Cyanobacterium sp. HL-69 TaxID=2054282 RepID=A0A2K8WNL3_9CHRO +-----------EKYANLQPSLFFVDLDNGAFV-NMNGMEAFPAASTIKTPILVAFFQDVD +EGKILLDEKLTMTEETKATEAGTMQYQPGTQYTALKVAEEMIIRSDNTATNMLIERLGGV +EALNQRFKEWGLESTVINNYLPDLEGM------NTISARDLAMTLVKVSNGDLVETRSRD +RLLGIMQRTIT-RTLLPQGIEPDAMIYHKTGDIGK-VLGDGGIIDIPTGKRYVGAVLVQR +PHND-YTARTMIQEISREAYQHf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. HDW15B TaxID=2714943 RepID=UPI00140D3470 +--ALRDQLRTITRAFDGSSGIAIVSLRDGWEA-SWNGDKLFPQQSCSKLWVAITAMDAVD +RGRIRLSNKVTLTRDDLTLHQPIRQKILTGPTTLGALLFQAVTESDNTANDRLLRAVGGS +EAVRAMIARKGLGAIRFYEGERKLQSRYLTNPYDGAAPRAVANALARLKAGQLLSPTSTA +ELLSIMGSTRTGKLRVRAGLAPGWSWNHKTGTGQIGGINDIGLLTAPDGAIYAMSIMTVP +NRAD-GGAQDLMQAVARAVIAQ- +>[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=X2L5P1_9BACT +-tSLQKQVEQLLEGKNVQVGIAVYY--QGKMLcTKNADQSFPMMSVFKLHQAVAILHCLK +QDSLTLKKPMLITKDMLSPYSPLRDKYPDGDLKVSQLIEYSVAQSDNNASNILFNLFDGT +HYANQVIQDLGCTNTQIKWTEDEMAMDHSRAYFNSTTPNDAILLLEMLVDNRTQRQQDFL +WLTEVMSGTQTGPNRLAKYLPTGTKLYHKTGTGYVKAVNDIGFVILPNGKHYSIAVFCKD +SKLSSEKTEELIAEISRLTYEY- +>[subseq from] Serine hydrolase n=2 Tax=Sphingomonas sp. 8AM TaxID=2653170 RepID=A0A654CP80_9SPHN +--ALQQRVTQLIRSFPGKAGAAIQAVDEDWIV-QEGGALYLPQQSVSKLWVAMTVLGQRD +AGRLKLDDPVLVTRDDLTLHQPVASLVTGEGTTVAGLLTRALTQSDNTANDRLLTYVGGP +AAVRRFLSEKRLPGIRFGPGERLLQSRYIDNPPDGAQPAAIVEALARLARGELLSETSTR +VLLETMANSHTGRARLKAATPVGWTLAHKTGTGQNAGFNDIGILTAPDGRRYAIAVQIGD +TTAPMRVRQVLIQQVAAAL---- +>[subseq from] Beta-lactamase class A n=2 Tax=Bacteria TaxID=2 RepID=A0A2T5GHJ2_9SPHN +--NLLNAVQALGISFKGDVGISVRDIDEGWVV-AWEGNNPRPQQSVSKFWVAIAVMDAVD +RGRLSLTDPVTVTRSDLTVHQPIRAFVGKDGTTIGDLLRGAMTRSDNTCNDVLLWRIGGP +AAINRMLDEKGIAGVGFGPGERQLQARYLSDPLDGASANGVTLGLSLLAQGKLLSAQSTT +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS +TRQPIPVRMRLMGNVTRAIVA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Anaerospora hongkongensis TaxID=244830 RepID=A0A4R1PTQ9_9FIRM +-kDIHAKLHAQLASFPGRCGLVIVNLANGEKW-EYCPETCFAAASMIKLPLMYEVMRQAA +AGLLSLDEYLTVTSEIQTGGAGILGELLPGLLTIRELVTLMIILSDNTATNMLIDRI-GM +DSVNNTAAALGLQSTILRRRMMDFEAA-ARGEENMTSAADLAQLFAHIYHPQLLSKEYGA +LMLDILKRQQV-RDKLPFYLPEEIEIAHKTGTLP-GVEHDGGILFLS--APYIICVLTDG +HTAN-YEGLQLVALIGKIIYE-- +>[subseq from] serine hydrolase n=1 Tax=Altererythrobacter soli TaxID=1739690 RepID=UPI001370938D +------------------------------------------------------------ +--------------------------------SALSLMDRMMVRSDNRATDLLIGALGGP +GAVDYWLRAQGLSGIRVDRNIAQLLGDRRWDIRDSSTPLAMLELLRLIDSDRALAPQSRA +LLLDMMRRCATGSNRIRGLMPYGAKVENKTGTLNQ-YTSDVGFLTLPDGRRVAVAFFARG +GE----NRPAVIATAARAIYDTf +>[subseq from] Beta-lactamase n=1 Tax=Cyanobacterium stanieri (strain ATCC 29140 / PCC 7202) TaxID=292563 RepID=K9YNW8_CYASC +----REKMTALFEKYHLQPSAFFVDLDNGAFV-NMNGIEAFPAASTIKTPILVAFFQDVD +EGNILLDEMLTMTEENRATEAGTMQYQPGTQYTALKVAEEMIIRSDNTATNMLIERMGGA +EALNQRFREWGLESTVINNYLPDLEGT------NTISARDLAITLMKVSNGDLVESRSRD +RLLGIMQRTIT-RTLLPQGIEPGATIYHKTGDIGK-VLGDGGIIDIPTGKRYVGAVLVQR +PHND-YTARTMIQEISREAYQHf +>[subseq from] Slr0121 protein n=1 Tax=Synechocystis sp. (strain PCC 6803 / Kazusa) TaxID=1111708 RepID=Q55897_SYNY3 +-------------------YSYFIDVDNGQFA-NAKGETQLPAASTIKIPVAIAFFEAVD +QGKIQLHEELPLTQDVIVGEAGTMQYDVGKRYPALEVVTKMIVISDNTATNMLIKRLGGK +EFLNQRFQAWQMPQTKINNYLPDLEGT------NTTSPQDLALLLVKLQGGELLSLKSRD +RLLGIMQQTKT-RTLLPQGLEPDAQIAHKTGDIGT-VLGDAGIVDMPNGKRYVGAVLATR +PHND-VAGRLLIQDISRTAYQHy +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. GH3-10 TaxID=2691582 RepID=UPI001365D5AE +-dALSATFDRIGQEFGGSLGIAVVDVDTGWST-GFNQNALLPQQSVSKTWVTLTALEMAE +KGQLDLDSPIRVSREDLTLHQPIRKEILRMGTTIGELIERAIQKSDNTANNAILQRVGGP +AAVRAMLARNGLEGIRFGPGEKPMQSNYLADPVDGATPIGIARALARIERGEVLSEKRAE +EFLTIMSNTSSGPRRLKGGRADGWVISHKTGTGQQSGYNDVGVLFAPDSSAYAVAVMIGV +TERPTIQRMDMMQSVTRAVIA-- +>[subseq from] Serine hydrolase n=1 Tax=Thermoanaerobacterium thermosaccharolyticum TaxID=1517 RepID=A0A231VM40_THETR +---LYDDIKRFINNTDGNIGVSIKNLKTGERI-DINEEMMFPSASTIKIVIMAQIFKMAK +EGYIRLTDNIILSDFMKTNGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM +KNINKMAEDLGMLHTKIQRKMMDFEAA-KSGKDNYTCPKDMTHLLELIHDGKVVDEEYSN +MMLDILKKQQD-LGRLDLYLPEDVLIAHKPGELKL-LEHDVGIVFLENCQ-YIISVMTNN +LSTN-LDGRRAIGKISKMVYDEy +>[subseq from] class A beta-lactamase-related serine hydrolase n=1 Tax=Synechocystis sp. CACIAM 05 TaxID=1933929 RepID=UPI00138E7C84 +-------------------YSYFIDVDNGQFA-NAKGETQLPAASTIKIPVAIAFFEAVD +QGKIQLHEELPLTQDVIVGEAGTMQYDVGKRYPALEVVTKMIVISDNTATNMLIKRLGGK +EFLNQRFQAWQMPQTKINNYLPDLEGT------NTTSPQDLALLLVKLQGGELLSLKSRD +RLLGIMQQTKT-RTLLPQGLEPDAQIAHKTGDIGT-VLGDAGIVDMPNGKRYVGAVLATR +PHND-VAGRLLIQDISRTAYQHy +>[subseq from] Beta-lactamase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2D8R0S9_9BACT +------------------------------------------------------------ +---------------------------------AYALMDRMMVRSDNRATDILINHLGGP +HAIEAWVESKGVTGMRVDRTIAQLLASKRWEHEDTSTPKAMLMLLHGIDRGGFLSASSRA +TILDMMRRCVTGRNRIKGLMPQGAIVEHKTGTLN-GYTSDVGYLTLPDGRRLAVAFFARG +GS----NRPAVIASAARSIYDGf +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. JS21-1 TaxID=1855283 RepID=A0A1H7FVD2_9SPHN +--RLVNAVQALGRGFKGAVGISVRNIDEGWVV-AWEGDRARPQQSVSKLWVAIAVMDAVE +HGRLSLADRVTVRRSDLTLHQPIRALVGKNGTTIGALLRGAMTRSDNTCNDVLLWKVGGP +SAINRMLREKGIDGVKFGPGERKLQARYLAAPMDGASANGVTLGLSLLAEGKLLTPRSTA +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS +THQPIPTRMRLMGNVTRAIVA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. UV9 TaxID=1851410 RepID=A0A4Q0GM86_9SPHN +--DLLNAVQALGAGFKGQVGISVRDIDEGWVV-AWDGDRPRPQQSVSKLWVAITVMDAVD +RGRLSLTDPVTITRADLTLHQPIRALVGKDGATIGELLRGAMTRSDNTCNDVLLWRVGGP +AAVNRMLADKGVVGVKFGPGERQLQARYLAAPIDGASANGITLGLSLLSQGKLLSTRSTA +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPSGHRYAVAVMIAS +TRQPIPVRMRLMGDVTRAIVA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V589_9BACT +------------------------------------------------VMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYGDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPQAMAKSLQNLTLGKALAEPQRA +QLVEWMKGNTTGGASIRAGLPTTWVV---------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI0011A6C11E +--ELQESLEKIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVQ +MGKVELKERIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK +ENVNQYMKEIGLSNTYIRLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH +DMFEILAKQQF-RGRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGNFIISVFSIG +NN-TEAEGACIISKLSRVAYNHf +>[subseq from] Class A beta-lactamase n=1 Tax=Muribaculaceae bacterium Isolate-002 (NCI) TaxID=2489215 RepID=A0A4Q0IZU1_9BACT +-kAIEVALQEYIQEKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSLMTVRELLEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS +EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD +SNYDIATTSAIIAEVSKIVLEGf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Mn802worker TaxID=629773 RepID=UPI00056AA66A +------------------------------------------------------------ +------------------------------------VMELMIVRSDNQAADQLLAAVGGP +GVVQQWLDAHGFAGIRVDRTIAQLLRGHLADVKDVATPIAMVALLSRLEDATVLTARSSG +FLFGLMRRCSTGTRRIRALLPPGTTVEDKTGTLD-GVTNDVGFITMPDGHRVAIAIFARG +GR----DRQPGIAAIARLVYDRf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas phyllosphaerae TaxID=257003 RepID=UPI000684ED23 +--ALQARVSQLIRSFPGKAGAAIQAVDEDWIV-SEGGTLSLPQQSVSKLWVAMTVLAQRD +AGRLKLDDPVLVTRDDLTLHQPIASLVTVQGTTVGALLTRALTQSDNTANDRLLNVVGGP +SAVRRFLAEKRLNGIRFGPGERLLQSRYIDNPPDGAQPAGIVEALARLARGELLSETSTR +VLLETMAASHTGRARLKAATPAGWTLAHKTGTGQNAGFNDIGLLTAPDGRRYAIAVQIGD +TTAPMRVRQVLIQQVAAAL---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Curtobacterium sp. HSID17257 TaxID=2419510 RepID=A0A433FL51_9MICO +------------------------------------------------------------ +-------------------------------LTVRALVDAALRQSDNTAANLLVERLGGV +GAVSRWLHGIGDDVTRVDRVEPDLNTAVPGDPRDTTTPAQSAADLRAVLLGDALDPDDRA +LLRSAMAGTTTGDGTIRAGVPDGWSVADKTGTASYGVRNDVAVVQPPGRDPIVLVVFTTR +DGAGAD----------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V588_9BACT +------------------------------------------------FMAASAILKESE +VKKNLLTQHVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP +NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMCIRAGLPATWIV---------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas jaspsi TaxID=392409 RepID=UPI0004B2CF1F +--ALNARIAEMGRAFDGKAGIAIVSLKDGWEI-GYGATALYPQQSCSKLWVAITAMDAVD +RGRVSLSDKVTLGRDDLTLHQPLADKILAGGTTLGALLFTAITESDNTANDKLMRSIGGP +SAVRTMIAAKGLGSIRFYEGERALQSRYVADPYDGAAPQSVARALARLKRGELLSAESTN +RLLSIMSQTRTGKLRVRAALPAGWSWSHKTGTGQIAGINDIGLLTAPDGTVYAMAIMTVT +NRS-DGNSQDLMQAVTRELVAY- +>[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI001446C780 +--ELQTPIKTLMARYKLSPGIFFMDLETGDYL-SINGDKSFAAASTIKYPILIALFQQVD +AGKIRLDETLVMGRKHIVGGSGNMQYRVGSKFSLLETATRMMTISDNTATNMIIDRLGGI +TQLNQKFRSWGLQNTVMRNRLGDFKGT------NKTSAKDLVKLSALMENNQLLSSTSEL +QVIGIMNGCRN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETSSGKRYLAGIFVRR +PNHD-ARAKDFIRQVSQVVYGYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf231 TaxID=1736301 RepID=A0A0S9CHS2_9SPHN +--ALQERVAQLVRSFPGKAGAAIQAVDEDWIV-SQGGTLYLPQQSVSKLWVAMTVLAQRD +AGRLKLDDPVLVTRDDLTLHQPIASLVTATGTTVGALLTRALTQSDNTANDRLLTVVGGP +AAVRRFLADKRLNGIRFGPGERLLQSRYIDNPPDGAQPSGIVEALARLARGELLSETSTR +VLLETMAASHTGRARLKAATPAGWTLAHKTGTGQNAGFNDIGLLTAPDGRRYAIAVQIGD +TTAPMRMRQVLIQQVAAAL---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudochrobactrum sp. C_NA_101_V4 TaxID=683079 RepID=D1LFD3_9RHIZ +------------------------------------------------------------ +-----LNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPASWVVG--------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Geminocystis sp. NIES-3708 TaxID=1615909 RepID=A0A0D6AIW7_9CHRO +---LKNKFAELKAKYKLEPGAFFVDLDNGAYV-NFNGTSNFAAASTIKIPILVAFFQDVD +AGKIYLDEKLTTTSSNIGSGSGGMQQPVGTQFSAIHTVTEMIINSDNTATNMIIERLGGK +NELNKRFKEWGLDMTVINNPLPDLEGT------NTTNPRDLAMVLVKVNQGDLISLRSRD +RLLEIMRQTKT-RTLLPQGIEEEASIAHKTGDIGT-ILGDAGIVDIPTGKRYIGAVLVKR +PYND-YSARTLIQEISRTGYQH- +>[subseq from] OKP-A beta-lactamase (Fragment) n=1 Tax=mine drainage metagenome TaxID=410659 RepID=T0YJU6_9ZZZZ +-----------------------LDLRTGLHA-SHRGGERFPMCSTWKVLAVAAMLQRVD +AGQERLDRRIRFDAHQLVSWSPVTERHVGGEMRVDALCAAALEISDNTAANLLLEALGGP +AAITRFARGLDDRVTRLDRYETALNEATPGDPRDTTAPDAMAGDLRRLLLGDAL------ +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=D1LFC0_ECOLX +------------------------------------------------------------ +-----LNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVG--------------------------------- +----------------------- +>[subseq from] Putative beta-lactamase n=1 Tax=Bacteroides sp. CAG:443 TaxID=1262739 RepID=R6MMD2_9BACE +-hTLESQIRQVTKSIRAQVGVAVI-IDGKDTV-TVNNDSRYPLMSVVKYPQSLAVAHFLH +QHNRPLSTEVFIAKEALYPYSPLRDEYPEGNLPISRLLEYTLQQSDNNACDILFEYIGGV +SYAERYIRSLGTECLAISKTEEQMYQAPESCYENWSSPLEMARLTDTLFSKELFPSDYQN +FIKETMLNCVTGENRLPQPLNTTARIGHKTGTSGRGGINDVGFVILPDGRRYSIAVLIKD +SKETMKATEKVIADISEIVYRY- +>[subseq from] Beta-lactamase n=1 Tax=cyanobacterium endosymbiont of Rhopalodia gibberula TaxID=1763363 RepID=A0A2Z5TLV6_9CYAN +-----EKVASQEKYAKVKPQGWFIDLDNGNYV-NFNGDTSLSAASTIKIPVLVAFFEELD +AGRIYLDEMLTMDEEIITGGSGSMQQKPGTKFSALEAATKMIVISDNTATDMLVRRLGGK +EALNKRFKEWGLTKTEINNRLPDLEGT------NTTSPKDLVELLARVERGDLLTVRSRD +RLLGIMQKTRT-QTLLPQGLEQGAIISHKTGDIGT-ILGDAGIIDIPTGKRYIGAVFAER +SYND-VMGRMVIQDFSRTVYQHf +>[subseq from] Peptidoglycan glycosyltransferase n=2 Tax=Nostoc sp. NIES-4103 TaxID=2005458 RepID=A0A1Z4S8M9_9NOSO +--QLNSQIKVLMARYSIEPGMFFLDLDTGNYL-DFNGEKAFPAASTIKFPVLVALFQEVD +AGRVKLNETLVMRRDLMTGGSGVMQKRSGTRFSLLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRNWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLSALIANNQVLSNSSRT +QVLNIMRRVKN-RSLLPSGLGKGAVIAHKTGTLGV-ILGDAGIIEMPSGKRYLAGIIVKR +PFND-LRGKAFITQVSRLVYG-- +>[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI0012614F94 +------------------------------------------------------------ +-----------------------------TDITLQTACQATMETSDNTAANLVLEKIGGH +AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSASRQ +QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ +TEATFDERNAAIVTIGKSIFDTf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella aquatilis TaxID=34038 RepID=U6A3Z6_RAHAQ +-------------------------------------------------MAASAILKESE +VKKNLLTQYVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP +NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWIVGD-------------------------------- +----------------------- +>[subseq from] AMIN domain-containing protein n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000C7F941E +--QLNTQVKGLMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD +AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS +KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIIVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] class A beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=UPI00125CC26A +-tSLQKQVEQLLEGKNVQVGIAVYY--QGKMLcTKNADQSFPMMSVFKLHQAVAILHCLK +QDSLTLKKPMLITKDMLSPYSPLRDKYPDGDLKVSQLIEYSVAQSDNNASNILFNLFDGT +HYANQVIQDLGCTNTQIKWTEDEMAMDHSRAYFNSTTPNDAILLLEMLVDNRTQRQQDFL +WLTEVMSGTQTGPNRLAKYLPTGTKLYHKTGTGYVKAVNDIGFVILPNGKHYSIAVFCKD +SKLSSEKTEELIAEISRLTYEY- +>[subseq from] class A beta-lactamase n=1 Tax=Bacteroides faecis TaxID=674529 RepID=UPI001106DDF3 +-tSLQKQVEQLLEGKNVQVGIAVYY--QGKMLcTKNADQSFPMMSVFKLHQAVAILHCLK +QDSLTLKKPMLITKDMLSPYSPLRDKYPDGDLKVSQLIEYSVAQSDNNASNILFNLFDGT +HYANQVIQDLGCTNTQIKWTEDEMAMDHSRAYFNSTTPNDAILLLEMLVDNRTQRQQDFL +WLTEVMSGTQTGPNRLAKYLPTGTKLYHKTGTGYVKAVNDIGFVILPNGKHYSIAVFCKD +SKLSSEKTEELIAEISRLTYEY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2W6WY67_9SPHN +----VSIIQSLGRNFNGDVGIAVKRVDADWVV-AYNGSKLYPQQSVSKLWVAMNLLDNVD +RGKLRMSDTVTVTRSDLTLHQPLAAMVGKDGTTYNDLFRRAMTESDNTANDMMLRKGGGP +EAVRGYLARRFISTIRFGPGERLLQSAYLANPPDGAAPIGIVTALAKLKRGEMLSPNSTQ +YLLSTMAQAKTGPQRVKGGVPFGWHYAHKTGTGQSTGYNDVGIMTAPDGTSYAIAVMIGS +TTVAIPERWALMQAVSRAVAEN- +>[subseq from] serine hydrolase n=1 Tax=Thermoanaerobacterium thermosaccharolyticum TaxID=1517 RepID=UPI00123AEC3F +---LYDDIKRFINNTDGNIGVSIKNLKTGERI-DINEEMMFPSASTIKIVIMAQIFKMAK +EGYIRLTDNIILSDFMKTNGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM +KNINKMAEDLGMLHTKIQRKMMDFEAA-KSGKDNYTCPKDMTHLLELIHDGKVVDEEYSN +MMLDILKKQQD-LGRLDLYLPEDVLIAHKPGELKL-LEHDVGIVFLENCQ-YIISVMTNN +LSTN-LDGRRAIGKISKLVYDEy +>[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5273 TaxID=2019663 RepID=A0A2N6KMV1_9CYAN +--QLNTQVKGLMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD +AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS +KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIIVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A0M3R6L4_KLEPN +------------------------------------------------------------ +-------------------------KTPCRRHTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPKKKAKRIVVIYL-- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas TaxID=13687 RepID=UPI000DEFE825 +------------------------------------------------------------ +------------------------------TLSAKTLMEAMLIHSNNVATDILIRNLGGP +RVVQEWIDFHRLSGIRVNRTIAQLLASPRDDIRDSATPEAMVTLLRQIDRGNVLTPQSRV +FLLSVMRRCATGSNRIRGLLDPTVLVEHKTGTLT-GLTSDVGFITMPDGRRVALALFARG +GS----DRPNSIAQAARTIYNGf +>[subseq from] serine hydrolase n=1 Tax=Citromicrobium sp. JLT1363 TaxID=517722 RepID=UPI001111BCFA +---LDDRLFALGTGLEGKIGIAVHDPARSRMM-HYNGTQLFPQQSVSKLWVALTALDQAD +RGELDLSETGTVRVDDLAVHNPIRRSVIANGTTYKDFLERALTASDNTANDMVLRRVGGP +DEVRKTLARKGFADIRFGPGERPMQSAYVADPVDGATPVAIASALARLHGGELLSQESTA +RYLAWLDDVKSGPNRLKGGLPDGWSIGHKTGTGQQAGYNDVGILTAPDGSIYTVAVMIGR +TQVPVPARMDMMHGVVRAVAG-- +>[subseq from] serine hydrolase n=1 Tax=Acidaminococcus timonensis TaxID=1871002 RepID=UPI0008D9D216 +-eQVKKRIASLCRQRAGTVAVDFYDETIGHGF-SFGGTRAVPSASTIKVLILAELLRQVE +QGLLSLEQPVTIRKEDYTGGDGILKELEPGHFTLKELATLMIIVSDNLATNRIIGLV-GM +ENVNALGKELGLQAARLGRRMMDSD-ALARGMDNWISAGDMGKLLRKIYEGTLVSQRASK +LMLDILKRQQQ-GERLQRYLPETVPLAHKCGDLD-GVENDGGIFLLPDH-PYILVVLTSH +MP-DNRSGRETIGRISRWVWE-- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium CG22_combo_CG10-13_8_21_14_all_63_91 TaxID=2014312 RepID=A0A2H0DQ87_9BACT +-eNMSAEIEKAARAYPARVAILIKDLNRGYTY-AYHADDLFPSASLIKVPIMVGVFDKIH +RGRLSLQSNLKLRRSTRMGGSGRLKWQRDGTFTVRQLLEQMMQRSDNTAMLLLIDEV-GM +GFLQNFFPTMGLVYTEIYPEGLRLTSG-RVRYENYTTAHEMAMLLEKAYKGKLVNSFASE +LMLDIMKGKK-GKTRLAKHLPVGWEIAHKTGLLRR-VCHDVGVVYSPNGD-YVVAVLTGR +NP-TYGRAKEFITEIGDITYKHy +>[subseq from] Beta-lactamase n=2 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=A0A2S5D179_LYSSH +---MQQTIQRLIQEAPYKVHMFVKDFKTNDFViHERLDDAFSSASLIKVPILIAVFDYID +VCNLPINQVITVTPSDWVDFSVISEQRVT-SCTIYELCVWMITTSDNTATNVLIDLI-GM +DVLNQYFHKIGLTQTQLQRKMMDFER-LAKGIDNITTARDMALLFSRIYEKNLLSPVFSQ +LVIDILCRQRF-HENLRRYIVDDVTIAHKTGGLDS-VDHDVGIVYSHGQ-EYAIGVFITE +VKQN-DVARQLIGRLSKVVYDN- +>[subseq from] Beta-lactamase n=1 Tax=Anabaena sp. WA102 TaxID=1647413 RepID=A0A0K2M3K8_9NOST +--ELQTPIKTLMARYKLSPGIFFMDLNTGDYL-SINGDKSFAAASTIKYPILVALFQQVD +AGKIQLDETLVMGKKHIAGGSGNMQYRLGSKFSLLETATRMMTISDNTATNMIIERLGGI +TQLNQKFRSWGLQNTVMRNRLGDFQGT------NKTSAKDLVKLSALMENNQLLSNTSQL +QVIGIMNGCHN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETPSGKRYLAGVFVQR +PNND-PRGTDFIRQVSQVVYGYf +>[subseq from] Beta-lactamase class A n=2 Tax=Lysinibacillus TaxID=400634 RepID=A0A1H8JLL9_9BACI +---LQESLEKIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVQ +MGKVELKEHIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK +ENVNQYMKEIGLSNTYIRLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH +DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPNKGNFIISVFSIG +NN-TEAEGASIISKLSRVAYNHf +>[subseq from] Serine hydrolase n=1 Tax=Thermoanaerobacterium thermosaccharolyticum TaxID=1517 RepID=A0A2G1CM45_THETR +---LYDDIKRFINSTDGNIGVSIKNLKTGERI-DINEEMMFPSASTIKIVIMAQIFKMAK +EGYIRLTDNIILSDFMKTNGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM +KNINKMAEDLGMLHTKIQRKMMDFEAA-KSGKDNYTCPKDMTHLLELIHDGKVVDEEYSN +MMLDILKKQQD-LGRLDLYLPDDVLIAHKPGELKL-LEHDVGIVFLENCQ-YIISVMTNN +LSTN-LDGRRAIGKISKMVYDEy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=D1LFB9_ECOLX +------------------------------------------------------------ +-----LNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVG--------------------------------- +----------------------- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Candidatus Margulisbacteria TaxID=2211321 RepID=A0A2W4I0T0_9BACT +--------------NGGTVGISIKDLTSEEYI-SINGDIQFNPASVIKVPVMAEVFHQLA +NGKLTLDKCIVLKRNNKVPGSGGLYYCQNGNYTIKHLVEKMITESDNTATNMLINFV-GM +NNINKYMNSLGLSQTVIKDDTMLSKK---PGYQNTTTPDDMLLLLDMMYQGKLVNKKYSL +QMLEIMSAQKH-KWGIRKYLPETLKIANKTGSLNS-VRNDIGIIFVKDK-PYILTIFAKQ +IPSD-FEATLFVRTISKLIYDK- +>[subseq from] Serine hydrolase n=1 Tax=Spirosoma pollinicola TaxID=2057025 RepID=A0A2K8YZH2_9BACT +--KLRQQIEQELSKQPGVFAVAFKDLSTGAEV-LIREHEVFHAASTMKTPVMIEVYKQAA +QHKLALTDTMTITTESIVDGSPYSYKAVGTKRTLAALVYNMIIISSNLATNMVIERV-GA +QNVTQTMRDLGARDIQVRRGVEDSKA-FTKGLNNTTTAYDLMLIFEKIATGKAVSPEASK +AMITTLLDQKF-NDAIPGKLPKEVKVAHKTGSIT-GVRHDSGIVFLPDGRKYVVVLLSKD +IK-DDKATIETMATVSEMIYKY- +>[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma fluviale TaxID=1597977 RepID=A0A286GPW8_9BACT +--ELRQQIEQELSKQPGVFAVAFKDLTTGKEL-LIREHEVFHAASTMKTPVMIEVYKQVA +QHKLSLKDSMTITTESIVDGSPYSYKAVGTKRTLAALVYDMIIVSSNLATNMVIERV-GA +QNVTQTMRELGAKNIQVRRGVEDSKA-FAQGLNNTTTAYDLMVIFDKIATGKAVSPDASK +AMITTLLDQKF-NDAIPGKLPKDVKVAHKTGSIA-GVRHDSGIIFLPDGRKYVLVLLSKE +IK-DDKATIQTMATVSEWIYK-- +>[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A525JHA5_9CAUL +--DLQATLERIAAGYGEPVGIAVSDVSAGWMA-EVGGEETYPQQSVSKLWVALAVLQAVD +DRRLSLDQTVVMHQEDRSVYQPLASRIRGAGISLADLMRHALIESDNAANDMLIREVGGP +GVVAHAIAQKHLAGLALGGTERDVQTTYLANPPDGATPVGIATALSALKRGELLSRSSTD +FMLELMGEARTGVLRLHAGLEPGWSLAHKTGTGPSVGINDVGLLTAPDGRTYAVAVMVRQ +TKQPPSARHRLMAGVARAVESYw +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas hengshuiensis TaxID=1609977 RepID=UPI000980EF44 +---LLNAVQGLGGGFAGSVGIAVRDIDEGWLI-SFNGAAALPQQSVSKLWVAIAVMDAVD +RGALSLSDPVTVRRSDLTVHQPIRALVGPDGTNVRALLEGAMTRSDNTCNDVLLWKVGGP +TAIRAMLARKHIEGVTFGPGERELQARYLAAPYDGASAQGVTLGLSLLARGTLLSPASSA +HLIGLMRASRTGPARMRAGLKPGWALAHKTGTGQTTGYNDVGILTAPDGHRYAVAVMIAS +TRVSIPVRQRLMANVVRAVIR-- +>[subseq from] Uncharacterized protein n=1 Tax=Trichormus variabilis SAG 1403-4b TaxID=447716 RepID=A0A433UQF6_ANAVA +--ELQTPIKKLMARYKLSPGIFFMDLETGDYL-NVNGDKSFAAASTIKYPILIALFQEVD +AGRIKLDETLVMGRKHMVGGSGNMQYRVGSKFSLLETATKMMTISDNTATNMVIDRLGGI +NKLNQKFRGWGLQNTVMRNRLGDFKGT------NKTSAKDLVKLSALMENNQLLSDTSEL +QVIGIMNGCHN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETPSGKRYLAGIFVRR +PNHD-ARAKDFIRQVSQVVYGYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. enrichment culture clone MS40-13 TaxID=979980 RepID=F1CKJ8_9PSED +------------------------------------------------------------ +---------------DLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSG--------------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Armatimonadetes bacterium Uphvl-Ar1 TaxID=2004467 RepID=A0A1Y0GZN4_9BACT +---IEAKLAALEKTNKCEIGAAIVT-PTETHF--SRKNERFSLQSVMKMVVSMTALHLVE +RGKWKLDQPFTFRFSDLSIHQPLSDELGNRNVTLDQLIELSTTESCSASVDFMIRKMGGT +KVVNEFLKKHDIKGMSVDREERELQTRYQIDPRDTTTPAAMADLLKKLVQGKLLSPEHTA +YFMGVMERTQTGPDRLKAGVPDGWILGHKTGTSSRSATNDVGYVRNESGEWKIIVALIRN +SKQTYEVREATIRQVAEVAFE-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas kaistensis TaxID=298708 RepID=UPI00143C4CF4 +------------------------------------------------------------ +--------------------------------SARALIESMMIKSNNQSTDLLIANLGGP +RAIQQWLDHNQIRGVRVDRNIARLLADKRWDLRDSSTPVAMVEMLRSLDKGNILTPANRA +YLLDVMARCSTGKNRIRGMLA-GVPIAHKTGTLNN-YTSDVGYLTLPDGRRLAVAFFARG +GT----DRPLTIAQAARTIYDGf +>[subseq from] HGE-1 beta-lactamase n=1 Tax=Clostridium sp. CAG:967 TaxID=1262849 RepID=R5KCJ4_9CLOT +---LSIKLNCLILNKDAVVGIAIIK--NQKEW-IIGSKNSLPMLSVFKYFVALKVLDKLE +KEKISLNKEITINKNMVDEYSQMLDKYKTFPISIANLLKYTISESDNNACDILIGYAGGT +KEIQEYINSIGFVDVEISETEFDMNKEIEKQYLNQARPIDIIRAMKFVRDRNILSDASCK +FLDEIMINTTTGKDKLKAGLPQNITLGHKTGSSSRKADNDTGYVFLPDGNVYYIAVMIKD +SKMSDEENAKLISSISKITYTHf +>[subseq from] serine hydrolase n=1 Tax=Cyclobacterium sp. GBPx2 TaxID=2716263 RepID=UPI00140C11C0 +-eDLKVAIQALIEDTEGDFGIAFKLLDSGSHL-LINEKEVFHAASTMKTPVMIEIFKQAG +SGKFSLDDSILIVNESIVDGSPYSYERIGEKATVYELMYQMIIKSSNLATNILIEEV-GA +ENVTQTMRDLGAADIEVLRGVEDLKA-FDAGLSNTTTALDMMLIMEAIASGEAVGQEESR +QMMDILYDQYY-KDLIPKLLPKEVKIAHKTGSIT-GVQHDAAILTLPDGKQYVLVILTKN +LT-DVEAGKEAIAEISKMIYD-- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium symbiosum TaxID=1512 RepID=A0A174H0T0_CLOSY +-eELKNRINEFIESQTGNICVALFDLKEQDGF-SIDGDRRVPSASMIKLVIMAELMRRVC +AGELSLEEKIKITQEMRTGGDGVLKEEPGHEFSLREILTLMIIVSDNEATNILIQML-GM +DRINRMAAELGLKEAVLGRKMMDSEA-KKQGRDNFICADDIMLILKKIYEGSCVDRKASA +LMLDILKRQQQ-SGRLQLYLPEDVEVAHKCGDLDF-LENDGGIILLPGH-PYILAVLTNG +VK-TNKDGREAIGRISQIIYEE- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFOXYB2_FULL_48_7 TaxID=1797967 RepID=A0A1F9XK05_9BACT +-------------SFPGEVGLYIKDLRTGVVV-AYNEDKKFASASLVKIPIMAAAYQAVE +DGNITLQEKLTLSQRLKASGSGMLKRFRRGTFTIDELLYHMITESDNTATNMITDKL-GY +GYVNWVFRNLGMQVTRMDRAIMDLRMR-SLGIENYTTAREMGEILEKIYNKKIISETACQ +DMLDILSHQKY-NDRIPRYLPEGLSVAHKTGLLR-GICHDAGIVFTPRGD-FVVCVLTSD +FG-SYRLAKNLIGEVAYKTYRAy +>[subseq from] Uncharacterized protein n=1 Tax=Blastopirellula marina TaxID=124 RepID=A0A2S8GMP6_9BACT +--ELSEALLPAIKRHKGEAAVLIKHLPSGATF-AYQADRPQGTASLIKLPVLMTLYKQVT +DGDVSLDALVEMKKEDQVPGSGILTGHFSPGLSVYDAAHLMITYSDNTATNLVIDQI-GL +PATKKLMKELGCPSTQLNSKVYRRDTSSQQYGLGVTSCSDMVRLLEMLHDGKFVDAATSK +KILAHLAFGDD-KSKVTRYLPAGVKPAHKTGAVNN-VRTDAGIIPLPEGA-LLFSVLTQN +NEGDKNEAELLAAEIGQVAYHYf +>[subseq from] Uncharacterized protein n=1 Tax=Blastopirellula marina TaxID=124 RepID=A0A2S8GMP6_9BACT +---------------------TVIDLDSGEAIgGADFDTVRDPASVTKIMTAHLVLTLAE +KSPEVLDETITFSERDKTPGST-SALKAGEKVSVGELLYGLMLPSGNDASVALAEHFGDI +AAMNKMAKSLGMTATGYANPHGLTAE------GHVTTAADMAKLARAAMQSERFRKIVAT +QQHATTVQSESGYERTNQLLEQEGFFGVKTGTTGPAGACLVSCCQRDGK-RLLMVVLGSS +STEA------------------- +>[subseq from] serine hydrolase n=1 Tax=Synechococcales cyanobacterium C TaxID=2690447 RepID=UPI00137A9656 +---VKAEVETLAAQSGLTPGAFFYSLDTGHFL-NLSGDRVFSAASTIKIPILIAFFQAVD +AGQVRLDESLVMRPDLIASEAGSIQYPPNSEYPALEIADLMITISDNTATNMLIDRLGGA +AALNQRFQSWGLQHTKIENLLPDLEGT------NLVSPMDLATVFLRLGEGELLSEASRT +KALEIMSRTVT-NTLLPQGLGEGASIAHKTGDIGS-VVGDAGLISTPNGQTYAAAVLVAR +PHND-SRAQELIRQISRITYTRf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. CF311 TaxID=2135485 RepID=UPI000E31FE6E +------AIDGITRNFDGLVGVAVTSVQDGWIVtSNDAARPMPQQSVSKLWVTMTVLDQVD +QGKIRLEDPITITRADFTLHQPIAALVKGDQATVGEIVRRAMQMSDNTCNDKLLRLVGGP +DAIRAFLARKGIAGVRFGPGERLLQAAYVRNPPDGAAAGAISVALARLKRGELLSPTSTD +WLLRTMDGAKTGRARVHGAVPPGWIYGHKTGTGQTAGFNDVGILTAPDGKSYALAVMIGD +TRRPIRERQMLMQQVAQAIVA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella aquatilis TaxID=34038 RepID=U6A3Y5_RAHAQ +-------------------------------------------------MAASAILKESE +VKKNLLTQHVGLKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP +HKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPAAWIVGD-------------------------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. CF311 TaxID=2135485 RepID=A0A2U0VJ25_9SPHN +----VSAIDGITRNFDGLVGVAVTSVQDGWIVtSNDAARPMPQQSVSKLWVTMTVLDQVD +QGKIRLEDPITITRADFTLHQPIAALVKGDQATVGEIVRRAMQMSDNTCNDKLLRLVGGP +DAIRAFLARKGIAGVRFGPGERLLQAAYVRNPPDGAAAGAISVALARLKRGELLSPTSTD +WLLRTMDGAKTGRARVHGAVPPGWIYGHKTGTGQTAGFNDVGILTAPDGKSYALAVMIGD +TRRPIRERQMLMQQVAQAIVA-- +>[subseq from] class A beta-lactamase n=1 Tax=Alistipes sp. Z76 TaxID=2304565 RepID=UPI001368D1EE +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRMTIRELLEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS +EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD +SNYDIATTSAIIAEVSKIVLE-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=D1LFB6_ECOLX +------------------------------------------------------------ +-----LNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVG--------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Gemmata massiliana TaxID=1210884 RepID=UPI00137B94C7 +--DLESRIAPLAKDHKGKVAVAVKHLKTGEEF-YLNADEAMPTASLIKLPVMVETYWQAH +EEKVKLDTKLTLTKDDKVGGSGILTSHFSDGFPLKDAVRLMIVYSDNTATNMVLDQI-GI +PSTNTRMEKLGLKNTKVHAKVFKGSTRTDKYGLGSTTAKEMVQLLELIETGKVASPEACK +EMLGHLKACDD-KEKMTRYLPAGTVVAHKTGSVN-ASKTDAGIVYLKSG-PVVLCVLTDG +NDDKDNAAQVLIGKIAKEVYEHy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella aquatilis TaxID=34038 RepID=U6A420_RAHAQ +-------------------------------------------------MAASAILKESE +VKKDLLTQHVELKKSDLVNYNPITEKHLNDGMTMGELAAAALQYSDNAAMNKLIEHLGGP +QKVTDYARTLGDKTFRLDRTEPTLNTAIPGDDRDTSTPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWVVGD-------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Synechocystis sp. (strain PCC 6714) TaxID=1147 RepID=A0A068MWC2_SYNY4 +-------------------YAYFIDVDNGRFA-NAKGETQLPAASTIKIPVAIAFFEAVD +QGKIQLHEELPLTEDVIVGEAGTMQYDVGKRYPALEVVTKMIVISDNTATNMLIKRLGGK +EFLNQRFQAWQMPQTKINNYLPDLEGT------NTTSPQDLALLLVKLQGGELLSLKSRD +RLLKIMQETQT-RTLLPQGLEPDATISHKTGDIGT-VLGDAGIVDMPNGKRYVGAVLATR +PHND-VAGRLLIQDISRTVYQHy +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Acidobacteria (miscellaneous) TaxID=305072 RepID=A0A1Q7CLG2_9BACT +-eKLEATINGVDRNLEGVLGVAILDLTTGQKY-FLHADEVLPTASSIKIAILAELYRQAQ +QGKIKLGDLYTLQSSDLAGGSGIAGALTPGVLTIRDVAVLMISVSDNSATNIIIDRI-GI +ENVNALLDSLSLTQTRLRRKMMDVKAA-GEGRENIATPREMVTLLESLYRGRVLNKPMTE +DFFTLLSVHKE--SYIPRELPEDLRIANKPGELE-GVRNDSGIVFTGSR-PFAISVMTTY +LRRE-KDGGDAIVRIATAAYQMf +>[subseq from] Beta-lactamase n=1 Tax=Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814) TaxID=580327 RepID=D9TTD1_THETC +---LYDDIKRFINNTDGNIGVSIKNLKTGERI-DINEEMMFPSASTIKIVIMAQIYKMAK +EGYIRLTDNIILSDFMKTNGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM +KNINKMAEDLGMLHTKIQRKMMDFEAA-KSGKDNYTCPKDMTHLLELIHDGKVVDEEYSN +MMLDILKKQQD-LGRLDLYLPEDVLIAHKPGELKL-LEHDVGIVFLENCQ-YIISVMTNN +LSTN-LDGRRAIGKISKLVYDEy +>[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Thermokryptus mobilis TaxID=1643428 RepID=A0A0S4N168_9BACT +-rKTFEKIKFIADTSNGVIGVAVKNLATGETF-LINENLIFPQGSAIKIPILIEVMKQAS +EGRFKLTDKIKIEKKHQVGGSGVLKEFADGLLSIYDLAVLMITVSDNTATNILIDLV-GM +ENVNKTLEKLGLKNTKLQRKMIRPDAS-ARGEENLSTPIEAMKLMEMLYKGEVISKDVSQ +KVLEILTKEKE--GSLGKYLPSDIKIANKPGGIE-GVNCEWGIVLLPRH-PYIIIVMSNY +NLK---SAQETIAQISKIVYEHf +>[subseq from] serine hydrolase n=1 Tax=Scytonema sp. UIC 10036 TaxID=2304196 RepID=UPI0012DA651D +--ALNSQIRALMDRYNLVPGMFFLDLQTGDYL-NINGDKAFPAASTIKFPILIALFQEIE +AGRVSLDEPLVMRRDLVAGGSGMQDKSVGSRFTVLQTATKMMTISDNTATNMIIDRLGGQ +VILNQRFHSWGLQNTAIRNLLADVNGT------NTTSAKDLVKLSALITNNKLINNTSRA +QVLEMMRHCHN-QSMLPSGLGSGAIIAHKTGTLRF-VLGDAGIIQTPTGKIYLAGILVKR +PNHD-SRATAFIRQVSRFVYDY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V595_9BACT +------------------------------------------------FMAASAILKESE +VKKNLLTQHVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP +NKVTNYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWIV---------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=3 Tax=Bacilli TaxID=91061 RepID=A0A160MD44_9BACI +--SLQDRLEEVLRDASGTFGVYVKHLETGETA-AINENRFFQAASVFKIPILAALYRDVH +LGKVNLQERIRLEEADLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKILRII-GK +ENVNQYMKEVGLNNTYIRFSCWELLCFQESIDNNVTTAFDMALLLEKIANKQLISEKACD +DMFEILEKQQF-RNRIPYLLPATTVVAHKTGTVAS-VVNDAGIVELPDNGRFIISAFSIG +NK-SEAEGARKIAELSRAAYGYf +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Rhodopirellula solitaria TaxID=2527987 RepID=A0A5C5X9A8_9BACT +-kQLAKLILPLIRSHQGQVNVMLKHLPSGATF-AHQADSVSGTASLIKLPLLVTLYDEVD +NGRADLDAMITLQAKDMVPGSGILTTQFSPGLSLRDAAHLMIVRSDNTATNLVIDAI-GL +DSTNEKMKSLGLTETRLNSKLYRRRTRSKLYGIGSTTPAEMVSLLERLHENQLFDKATTK +QVTSHLYACDD-TTKFQRYLPAGARIAHKTGYVDD-IRTDAGWVETVDGT-MLYCVMTHD +NVSDQNSADLVIGEIGRIAYETf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas trueperi TaxID=53317 RepID=UPI0011522B17 +--ALLNAVQALGAGFQGQVAISVRDVDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID +HKRLSLATPVTVTRADLTVHQPIRPLVGPSGTTVGALLECALTRSDNTCNDVLLWKVGGP +AAIRHMLKEKGVDGVEFGPGERELQARYLAEPYDGATANGVTLGLSLLAKDKLLSHASTE +RLSRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS +TRQPIPVRMRLMGDVTRAVIR-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0013A6FC3A +------------------------------------------------------------ +------------NKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +TKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] class A beta-lactamase n=1 Tax=Bacteroides uniformis TaxID=820 RepID=UPI00129C4AFB +-tSLQKQVEQLLEGKNVQVGIAVYY--QGKMLcTKNADQSFPMMSVFKLHQAVAILHCLK +QDSLTLKKPMLITKDMLSPYSPLRDKYPDGDLKVSQLIEYSVAQSDNNASNILFNLFDGT +HYANQVIQDLGCTNTQIKWTEDEMAMDHSRAYFNSTTPNDAILLLEMLVDNRTQRQQDFL +WLTEVMSGTQTGPNRLAKYLPTGTKLYHKTGTGYVKAVNDIGFVILPNGKHYSIAVFCKD +SKLSSEKTEELIAEISRLTYEY- +>[subseq from] Beta-lactamase-like protein n=1 Tax=Clostridium sp. MSTE9 TaxID=1105031 RepID=J0N280_9CLOT +----EEKIREYLNLQPGEQAVFIKDLTDGETF-CFNEKAVFPSASTIKLVIMACLLDQVK +TGRLSLEDPVVLTEEMRTGGDGILKELSAGHFSLREILTLMIIVSDNTATNILIQLL-GM +DAINEMAGRLRLSRTVLGRRMMDSEA-RKQGKDNYTCADDIAHILELIYEQKCVDVPSSR +LMLDILRRQQQ-SGRLQLYLPEEVEIAHKCGDLDF-LEHDAGIILLPKR-PYLIVVLTRD +NP-TNKDGREVIGTVSRMVYEE- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Elusimicrobia bacterium RIFOXYD12_FULL_66_9 TaxID=1797972 RepID=A0A1F9YKV6_9BACT +---MIADLDKLSSRYPGRVSIFLRDLRTGKTW-MHHPDDLFPAASLIKVPILIAAFYKMK +DGQLSLDEKLTISRRNRVGGSGSLKWRPDGTLKVRDLLLYMINESDNTATKMILERL-GL +GYVQQQFPRMGLLYTGIYEEGMSLKGG-RVAHENYTTAREMTMLLEKIYKGEAVDKASSE +YMMEILKHPKAAQSRLAKGLPTGWEIAHKTGLLRQ-ACHDSAIFLTPNGD-YTMTVLTGQ +NQ-SYSQAKTLITKLAHVTFANy +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. MBR 210 TaxID=1881015 RepID=A0A1C0VNW7_9NOSO +--QLRSRVQALATKYSLDPGLFFLDLDTGNYL-DFNGEKVFPAASTIKFPILVALFQEID +AGRIKLNETLVMRRDLITGGSGEFQKRAGTRFSLLETATKMITISDNTATNMIIDRLGGK +ARLNPRFRSWGLQNTVVRNLLGDFKGT------NTTSAKDLVRLSALVANNRLLSDSSRG +RVLNIMQRVRN-TKLLPAGLGKGAVIAHKTGTLGI-VLGDAGIIQMPSGKRYLAGIFVRR +PFNDL-KARDFINQVSRIVYG-- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Muribaculaceae TaxID=2006847 RepID=A0A3N2L6S1_9BACT +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRMTIRELLEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS +EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSVAVFVAD +SNYDIATTSAIIAEVSKIVLE-- +>[subseq from] Uncharacterized protein n=1 Tax=Cyanobacteria bacterium UBA9971 TaxID=2055776 RepID=A0A353QTI9_9CYAN +--NLTNQLKYLAAAYQLETGIFIWDYNTGGYV-DINGDKIFPTASIIKLPVLFQIFRRSE +KGLINLNDKISLTNYYITGGSGSLQYSPGTKHTYRHLAALMIQESDNTATNMLLSSVGGM +NELDREIKNWGLKSTSLSNWLPDLDGT------NVSTPREMGTLLYNIGNTNLLSIKTRA +EIVDIMSHVRN-NRLIQAGLPADAGFIHKTGDIGT-MLGDAGVVALPDGRKYVIVIMVKR +PWNS-FAAKEFIIEASKITYNSy +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas pokkalii TaxID=2175090 RepID=A0A2U0SIU5_9SPHN +--ALVNRLSEVARNFDGVVGIAVTSVDRNWTA-SQGGARRLPQQSVSKLWVAMTVLDQVD +QGRIRLSDPLVITRADFTLHQPVASLVKGDQSTVGEIMRRALTMSDNTCNDKLLRLVGGP +PAVRSFIARNALGSIRFGPGEKLLQLSYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ +WLLSTMQASHTGKHRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSFALAVMIGD +TPRPINERQLLMHAVVRAVVAE- +>[subseq from] Serine hydrolase n=1 Tax=Thermoanaerobacterium thermosaccharolyticum TaxID=1517 RepID=A0A223HXB4_THETR +---LYDDIKRFINNTDGNIGVSIKNLKTGERI-DINEEMMFPSASTIKIVIMAQIYKMAK +EGYIRLTDNIILSDFMKTNGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM +KNINKMAEDLGMLHTKIQRKMMDFEAA-KSGKDNYTCPKDMTHLLELIHDGKVVDEEYSN +MMLDILKKQQD-LGRLDLYLPEDVLIAHKPGELKL-LEHDVGIVFLENCQ-YIISVMTNN +LSTN-LDCRRAIGKISKMVYDEy +>[subseq from] Uncharacterized protein n=1 Tax=Omnitrophica WOR_2 bacterium SM23_72 TaxID=1703777 RepID=A0A0S8ILD3_9BACT +-sKLSQEISQEISQFKGKVGIVIKDLDKDWEL-FYNKQMLFPSASLAKVPLMAASFLAAQ +EGRLKLERNVKLKSSDKFSGSGILKDHPGVEFSVEELIGLMIYDSDNTATNMVTGMV-GI +NYLNNFFKNIGLKNTNLARRIADYSSR-KRGIENYTTAEDMAWILEKIYRKTLINKDISE +RCLKLLKLQRY-NDRIPKYLPVELTIAHKTGLER-GICHDTGIVYTPKGD-FLICVLTKH +ENANSVPSKEFIAKISLYVYHYf +>[subseq from] Uncharacterized protein n=2 Tax=Calothrix desertica TaxID=32056 RepID=A0A3S1CGC0_9CYAN +---LNSQIRALMSRYSLSPGMFFVDLQTGDYI-DINGNKVFSAASTIKLPILITLFQEIE +AGRVRLDDTLVMRRDLVAGGSGDMQNMRTGKFTVLETATKMMTISDNTATNMIIDRLGGF +SRLNERFRSLGLQKTALRHLLADEYG------TNTTSAKDLVHLSSLIANNQILSDGSRA +QILDIMRRCHN-QSMLPSGLGAGAVIAHKTGTLRF-VLGDAGIIQTASGKRYLAGILVKR +PNHD-KRATAFIRQVSHIVYDY- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Gemmata sp. SH-PL17 TaxID=1630693 RepID=A0A142XHT1_9BACT +--DLESRIAPLAKDHKGKVAVAVKHLKTGEEF-YLNADEAMPTASLIKLPVMVETYWQAQ +EGKVKLDTKLTLTKDDKVGGSGILTSHFSDGFPLKDAVRLMIVYSDNTATNMVLDQI-GI +PSTNTRMEKLGFKNTKVHAKVFKGSTRTDKYGLGSTTAKEMVQLLELIEAGKVASPEACK +EMLGHLKACDD-KEKMTRYLPAGTVVAHKTGSVN-ASKTDAGIVYLKSG-PVALCVLTDG +NDDKDNAAQVLIGKIAKEVYEHy +>[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter xiamenensis TaxID=1316679 RepID=A0A1Y6F7K3_9SPHN +---FERRIAQLADGTRGRIGVYAIDLSSGDEV-SVLGDQFFPMASTSKVAVAATYLAGVD +EGRWGLTSEWQLPR------------RGGAHVPAYRLIELMISKSCNDCTDALLDAVGGP +AAVNAWVKKAGISGFNLNRNIRALIRASVVDTRDAATPRAMGQLLAGIYQGRWLSSSSRQ +VILDSMEQTTTGKRRMRSAVPLSAKLAHKTGTLSR-TASDIGIFHTPDGRPIAVAIYVTG +QSPSMAVEN-------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. LM7 TaxID=1938607 RepID=A0A1S6FL18_9SPHN +---LVTSIDSITRNFAGLAGIAVTSVDDGWIAsNATASRPLPQQSVSKLWVAMTVLDAVD +RGTVRLDDPLTITRSDFTLHQPIAALVKGDVTTVGEIMRRAMQMSDNTCNDKLLRLVGGP +QAVRDFIARKQLGTIRFGPGEKLLQAAYIKDPPDGAAPIAIADSLARLQRGELLSPNSTA +WLLATMGGAKTGKARVRGAVPPGWLYGHKTGTGQTAGFNDVGILTAPDGRSYAVAVMIGD +TARPIRERQLLMQAVASAIVAH- +>[subseq from] serine hydrolase n=1 Tax=Clostridium jeddahense TaxID=1414721 RepID=UPI0004BB4233 +----EEKIREYLNLQPGEQAVFIKDLTNGETF-CFNEKAVFPSASTIKLVIMACLLDQVK +TGRLSLEDPVVLTEEMRTGGDGILKELSAGHFSLREILTLMIIVSDNTATNILIQLL-GM +DAINEMAGRLGLSRTVLGRRMMDSEA-RKQGKDNYTCAGDIAHILELIYEQKCVNVPSSR +LMLDILRRQQQ-SGRLQLYLPEEVEIAHKCGDLDF-LEHDAGIVLLPIR-PYLIVVLTKD +NP-TNKDGREVIGTVSRMVYEE- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8W2V0_9BACT +-qKLEATINGVDRNLEGVLGVAILDLTTGQKY-FLHADEVLPTASSIKIAILAELYRQAQ +QGKIKLGDLYTLQSSDLAGGSGIAGALTPGVLTIRDVAVLMISVSDNSATNIIIDRI-GI +ENVNALLDSLSLTQTRLRRKMMDVKAA-GEGRENIATPREMVTLLESLYRGRVLNKPMTE +DFFTLLSVHKE--SYIPRELPEDLRIANKPGELE-GVRNDSGIVFTGSR-PFAISVMTTY +LRRE-KDGGDAIVRIATAAYQMf +>[subseq from] Serine hydrolase n=2 Tax=Lysinibacillus TaxID=400634 RepID=A0A410MP42_LYSSH +---LQESLEKIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVQ +MGKVELKEHIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK +ENVNQYMKEIGLSNTYIRLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH +DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGNFIISVFSIG +NN-TEAEGASFISKLSRVAYNHf +>[subseq from] Peptidoglycan glycosyltransferase n=2 Tax=Fischerella sp. NIES-4106 TaxID=2005456 RepID=A0A1Z4TF85_9CYAN +--QLNTQVKALMARYNLQPGIFFLDLDTGNYL-DLNGEKVFPAASTIKFPILVALFQEVD +AGRVKLNETLVMRRDLMTGGSGTLQKRPGIKLSVLETATKMITISDNTATNMIIDRLGGK +ARLNQRFQSWGLQNTMIRNLLGDFKGT------NTTSAKDLVRLGALLSNNQLLNDGSRS +QALDIMRHVKN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] class A beta-lactamase n=1 Tax=Parabacteroides johnsonii TaxID=387661 RepID=UPI00101D8EF0 +-kAIENALQEYIKGKDARIGIAII-INGKDTV-SVNGNRDFPMMSVVKFPLALTVANWVD +TNNMSLSDTVTFSGKSLKEYSPMLKKYGKSRMTVRELLEWSLVESDNNAADILLNCVGGV +SGATSKMRQIGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFNNEMRNASQSYS +EISVMLKQCRTGLDRLALLLPTNATIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD +SGYDMAATSAIIAEISKIVWK-- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5ZLY8_9BACT +-kKLETRVREIADRLDGVVGVAILDLTDGRAL-LHNADRVFPTASSIKIAILLELYRQDQ +KGKAKLDDVYTFNPKDLVDDSRIMAGLTAGVVTNRDLAQFMVAVSDNAAANILIDRV-GR +DKVNAMLQGLGLSKTLLRRKMMDIAAAKRG-DENVATPHEVVRLLDAIQKEKVLNNESTA +QFIKQLSTKK--DSYIPRYLPDDVQVANKPGDLE-GVRNDSGIVYAKNR-PFAISVMTAY +DR-DEKAAERAISELALEAYHYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella aquatilis TaxID=34038 RepID=U6A729_RAHAQ +-------------------------------------------------MAASAILKESE +VKKDLLTQHVELKKSDLVNYNPITEKHLNDGMTMGELAAAALQYSDNAAMNKLIEHLGGP +QKVTDYARTLGDKTFRLDRTEPTLNTAIPGDDRDTSTPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPAAWVVGD-------------------------------- +----------------------- +>[subseq from] Beta-lactamase class A n=2 Tax=Synechococcus sp. (strain ATCC 27167 / PCC 6312) TaxID=195253 RepID=K9RYG3_SYNP3 +--QVEKTIQQWAAKKQLQGGAYFLNLTTGNSV-NVDGTQIVAAASTIKIPVLVALFQALD +RGEITLAEPLTMRPDLIAGEAGTMQQKPGTKFSTLETAELMISISDNTATNMLIDRLGGA +TILNDQFVQWGLEHTVIRNPLPDMEGT------NTTSPKDLAILMARIAQGDLVSQTSRE +KLLGIMRTTVT-NTLLPQGLGPGAKIAHKTGDIGT-FVGDAGLIEMPNGQQYVAGIMVKR +PYND-PQGTELIRQISRLTYQAy +>[subseq from] Serine hydrolase n=1 Tax=Anabaena sp. MDT14b TaxID=1710886 RepID=A0A1B7WLX7_9NOST +--ELQTPIKTLMARYKLSPGIFFMDLETGDYL-SINGDKSFAAASTIKYPILVALFQEVD +AGKIQLDETLVMGRKHIVGGSGNMQYRVGSKFSLLETATRMMTISDNTATNMIIDRLGGI +TQLNQKFRSWGLENTVMRNRLGDFKGT------NKTSAKDLVKLSALMENNQLLSSTSEL +QVIGIMNGCRN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETSSGKRYLAGIFVRR +PNHD-ARAKDFIRQVSQVVYGYf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9K5B2_9BACT +hsELEGELDRVADRLDGVVGYAIKDFSTGEAF-YRNADLVFPAASSIKLAVLLELTRQAQ +EGKLSLDEKHTVRRSETVAGDPILYMLGDGTMTLRDLAVFMVVLSDNSATNILIDRV-GM +ENVNAGVARLGLKETRLRRHMIDIEAA-RRGNENVSTPRELAVLLEKVRNGQVLDSVHSQ +DYFSILRLPKD--SLFSKALPPGVPVEDKPGALD-AVRCDAGIIEAEGH-PFVVSVMTTF +LA-SNEEGERAIKEIARLAYAHf +>[subseq from] hypothetical protein n=1 Tax=Phormidesmis priestleyi TaxID=268141 RepID=UPI0009ECD0B4 +----KNDIQTLVAQQQLNSSVMLVDLDTNAFL-NINASVALPCASTIKLPVLVAFFQDVD +AGKIHLDELLTMRPDLIATESGEMQYQPPGTFTALETATKMITVSDNTATNMLIDRLGGK +DVLTQRFQSWGLTSTAIRNPLPDIAGT------NTSSSQDLVTALGLVTNGKLMSLRSRD +RLLDIMRRTAN-SSLLPTGLGEGATIAHKTGSIGT-LIGDVGVVDMPSGKRYLIGALVKR +PR-DDERAEELIRKVSRLTYQYf +>[subseq from] Beta-lactamase/transpeptidase domain-containing protein n=1 Tax=Anabaena sp. 90 TaxID=46234 RepID=K7W3G2_9NOST +--ELQTPIKTLMARYKLSPGIFFMDLETGDYL-SINGDKSFAAASTIKYPILIALFQQVD +AGEIQLDETLVMGRKHIVGGSGNMQYKVGSKFSLLETATRMMTISDNTATNMIIDRLGGI +TQLNQKFRSWGLENTVMRNRLGDFKGT------NKTSAKDLVKLSALMENNQLVSNTSEL +QVIGIMNGCRN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETSSGKRYLAGVFVQR +PNHD-ARAKDFIRQVSQVVYGYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A2E1YY57_SPHSX +--ALTAIIQSAVRNFDGKAGVAVESVDDGWIV-SANGETLMPQQSVSKTWVAMTVLAQRD +EGRLSLDDPLTITTADLTLHQPIAALVQKNGSTVGEIMKRALTMSDNTCNDKLLWLVGGP +PAVRAFIESRKLGAIRFGPGERLLQSAYIANPPDGAAPVAIADALARLKRGELLSAGSTS +WLITTMQSSHTGRNRLRGEVPGDWLFGHKTGTGQTAGYNDVGILTAPDGRSYTVAVMIGD +TARTIPQRWELMHTVVKAIVN-- +>[subseq from] Beta-lactamase class A n=2 Tax=Tissierella praeacuta TaxID=43131 RepID=A0A1M4TR86_9FIRM +------------DSVDEEVSIIIKDLTNDRWIlKYNEDRVFPSASLIKIPIMIEVLERVE +KGELSLDKKIKIKAIDRVDYSIISELTLK-EYTLIDLITLMIILSDNTATNVLIDLL-GY +EKVNETVKKLNCNNTILKRKMMDFTAA-KEGRENLTSPMDMALFMEKIYNKSIISPKICD +VMIDILTRQKH-RDMLPRYILDEVKIANKTGELS-GINHDIGIFYLENIN-YLIGIFTTN +GK-DDLVGKRTIGRISKLVYDNf +>[subseq from] serine hydrolase n=1 Tax=Calothrix sp. PCC 7103 TaxID=32057 RepID=UPI00035CE78C +---LNSQIRALMSRYNLSPGMFFVDLQTGDYI-DINGDKVFSAASTIKLPILITLFQEIE +AGRVRLDDTLVMRRDLVAGGSGDMQNRVGKKFSVLETATKMMTISDNTATNMIIDRLGGF +SRLNERFRSLGLKNTALRHLLADVYGT------NTTSAKDLVHLSSLIANNQILNDGSRT +QILDIMRRCHN-QSMLPSGLGAGAVIAHKTGTLRF-VLGDAGIIQTASGKRYLAGILVKR +PNHD-ERAIAFIRQVSHIVYDY- +>[subseq from] serine hydrolase n=1 Tax=Tissierella praeacuta TaxID=43131 RepID=UPI001047B974 +------------DSVDEEVSIIIKDLTNDRWIlKYNEDRVFPSASLIKIPIMIEVLERVE +KGELSLDKKIKIKAIDRVDYSIISELTLK-EYTLIDLITLMIILSDNTATNVLIDLL-GY +EKVNETVKKLNCNNTILKRKMMDFTAA-KEGRENLTSPMDMALFMEKIYNKSIISPKICD +IMIDILTRQKH-RDMLPRYILDEVKIANKTGELS-GINHDIGIFYLENIN-YLIGIFTTN +GK-DDLVGKRTIGRISKLVYDNf +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=UPI00084A423A +----QQTIQRLIQEAPYKVHMFVKDFKTNDFViHERLDDAFSSASLIKVPILIAVFDYID +VCNIPINQVITVTPSDWVDFSVISEQRVT-SCTIYELCVWMITTSDNTATNVLIDLI-GM +DVLNQYFHKIGLTQTQLQRKMMDFER-LAKGIDNITTARDMALLFSRIYEKNLLSPVFSQ +LVIDILCRQRF-HENLRRYIVDDVTIAHKTGGLDS-VDHDVGIVYSHGQ-EYAIGVFITE +VKQN-DVARQLIGRLSKVVYDN- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8G5G9_9BACT +-eHVQRQLRDVASSFDGVMGYDVVDLTDGRTF-GALQDDVFPTASSIKLALIYELFKQVD +EGRIALEDVRPLNPAFKVGGSGVLHELTTPSLSIRDYATLMVVLSDNTATNVLIDAV-QM +TRVNDRMTALGLGHTKLRRRMMDREAALRGD-ENVSTPAELAKLLQIMYRGDGLTPASRD +TLIAILKKSKD--TPLRRGVPPNVDVANKPGDLE-GVATDAGIVYVKNR-PYVLAVMTSY +AN-DGGGGARAIEAASRAVYDYf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. CCH5-D11 TaxID=1768786 RepID=UPI0009E97EB8 +--ALLNAVQALGRGFSGDVGISVRDIDEGWTV-DWAGDKPRPQQSVSKLWVGITVMDAVD +RGRMSLSDPVTVRKSDLTVHQPIRPLVDSDGTKVGALLQGAMTRSDNTANDVLLWRAGGP +EAVRRMLEEKDVAGVTFGPGERLLQARYLADPEDGASANGVTLGIALLAQGKLLSPASTD +KLLSLMRASRTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS +TRQSIPSRMRLMGDVSRAIVA-- +>[subseq from] Serine hydrolase n=1 Tax=Calothrix sp. HK-06 TaxID=1137096 RepID=A0A1Q4RXL7_9CYAN +---LNSQIRALMSRYNLSPGMFFVDLETGDYI-DINGDKAFSAASTIKLPILITLFQEIE +AGRVRLDDTLVMRRDLVAGGSGDMQNMRTGKFTVLETATKMMTISDNTATNMIIDRLGGF +SRLNERFQSLGLQNTALRHLLADEYG------TNTTSAKDLVHLSSLIANNQILSDGSRT +QILDIMRRCHN-QSMLPSGLGAGAVIAHKTGTLRF-VLGDAGIIQTASGKRYLAGILVKR +PNHD-ERATAFIRQVSHIVYDY- +>[subseq from] serine hydrolase n=1 Tax=Actinomadura rayongensis TaxID=1429076 RepID=UPI001355D5BA +--KALDELARRAEARGGVLGVVVQG-ASGERA-SVNADRTFTAASLIKLPVLLALLDGVE +AGRWSLDDRLPVR--DRVGGAGILRDLADVALSVRDLVSLMIVISDNTAANLLIDRI-GQ +HTVADWCARHGLHATVLARRMMDAEA-RERGEENRTSPADMATLLDGLVRGTLLGPAATA +FALDVLARQQV-RDRLPRDLPDNVRIAHKTGELD-GIRHDVGVIFTN--TPIVVAALTEN +TE----EADDLIAETARRAVQ-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. 22-7 TaxID=2709707 RepID=UPI0013D14A57 +--SLKDRLEEVLRDASGTFGVYVKHLETGETA-AINENRFFQAASVFKIPILAALYRDVH +LGKVNLQERIRLEEADLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKILRII-GK +ENVNQYMKEVGLNNTYIRFSCWELLCFQESIDNNVTTAFDMALLLEKIANKQLISEKACD +DMFEILEKQQF-RNRIPYLLPATTVVAHKTGTVAS-VVNDAGIVELPDNGRFIISAFSIG +NK-SEAEGARKIAELSRAAYGYf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A0P0LKQ2_BACVU +-kTIEKALLEYVSDKDARIGIAVI-VNGTDTV-SVNGKRDFPMMSVVKFPLALTVVQWID +ANGLSLNDSIAFSEKALKEYSPMLKRYGKKRMTIRELLEWSLVESDNNAADILLNHVGGI +SGATKIMRKIGVDNIEIGASEDDMHRDPYLSYLNRTTPLAMAQLFDRFDTEMRNTSLSYS +EIATMLEQCRTGIDRLVALLSSDATIGHKTGTGFISAINDCGYVNLPNGERYSIAVFVAD +SGYDMAETSAIIAEISRIVW--- +>[subseq from] serine hydrolase n=1 Tax=Pseudanabaena sp. PCC 6802 TaxID=118173 RepID=UPI0012E9995F +--ALTAKIKQLAAESDLSLQTLVFDADTGVYT-DVNSRKPIASASIIKIPLLIAFLQDVD +EGKVQLGEQLEISKDVIVGEAGGLQYEPEGTISALETLTEMIVHSDNTATNMIMKRIGGK +DAANRRFKSWGLNSTVIRNQLPDLEGT------NTTSPYDLVNLLSMVDKGKLLSPRSRD +RLMDIMRRPVT-NTLLPQGIAADARIVHKTGDIRS-VVGDAGIIDMPSGRRYIMAAIVKR +PDND-QRANELIRQVSRATYDY- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A520VEU9_9SPHN +---LEQQIAQLADGSDGRIGVYAIDLSTGREV-GVLADQRFPMASTSKVAIAATFLAGVD +ANRWSLTSEYRLPR-------------PGGALPAYRHLSLMISKSCNDCTDALLAAVGGP +SAVNKWMKDAGIEGFSLSRDIATLIRAWSVDIKDSATPRAMGQLLAGIYQGKWLSDYSRR +VLLDAMEETTTGKRRMPSALPVSANLAHKTGTLAR-TASDIGIFHTPDGRAIAAAIYVTG +QSPSMAVE--------------- +>[subseq from] Beta-lactamase n=6 Tax=Sphingomonadales TaxID=204457 RepID=A0A2D5F3P5_9SPHN +---LEQQIAQLADGSDGRIGVYAIDLSTGREV-GVLADQRFPMASTSKVAIAATFLAGVD +ANRWSLTSEYRLPR-------------PGGALPAYRHLSLMISKSCNDCTDALLAAVGGP +SAVNKWMKDAGIEGFSLSRDIATLIRAWSVDIKDSATPRAMGQLLAGIYQGKWLSDYSRR +VLLDAMEETTTGKRRMPSALPVSANLAHKTGTLAR-TASDIGIFHTPDGRAIAAAIYVTG +QSPSMAVE--------------- +>[subseq from] serine hydrolase n=1 Tax=unclassified Erythrobacter TaxID=2633097 RepID=UPI0007B87384 +---LEQQIAQLADGSDGRIGVYAIDLSTGREV-GVLADQRFPMASTSKVAIAATFLAGVD +ANRWSLTSEYRLPR-------------PGGALPAYRHLSLMISKSCNDCTDALLAAVGGP +SAVNKWMKDAGIEGFSLSRDIATLIRAWSVDIKDSATPRAMGQLLAGIYQGKWLSDYSRR +VLLDAMEETTTGKRRMPSALPVSANLAHKTGTLAR-TASDIGIFHTPDGRAIAAAIYVTG +QSPSMAVE--------------- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. HI0028 TaxID=1822227 RepID=A0A176E195_9SPHN +---LEQQIAQLADGSDGRIGVYAIDLSTGREV-GVLADQRFPMASTSKVAIAATFLAGVD +ANRWSLTSEYRLPR-------------PGGALPAYRHLSLMISKSCNDCTDALLAAVGGP +SAVNKWMKDAGIEGFSLSRDIATLIRAWSVDIKDSATPRAMGQLLAGIYQGKWLSDYSRR +VLLDAMEETTTGKRRMPSALPVSANLAHKTGTLAR-TASDIGIFHTPDGRAIAAAIYVTG +QSPSMAVE--------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Duncaniella sp. TLL-A3 TaxID=2530391 RepID=A0A4Z0V2U1_9BACT +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRMTVRELLEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS +EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNFPNGTRYSIAVFVAD +SNYDIATTSAIIAEVSKIVLE-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044788EE +------------------------------------------------------------ +------------NKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Nostoc piscinale CENA21 TaxID=224013 RepID=A0A0M4SVF1_9NOSO +--QLRSRVQALASRYSLDPGLFFLDLDTGNYL-DFNGEKVFPAASTIKFPILVALFQEID +AGRIKLNETLVMRRDLITGGSGEFQKRAGTRFSLLETATKMITISDNTATNMIIDRLGGK +AKLNPRFRSWGLQNTVVRNLLGDFKGT------NTTSAKDLVRLSALVANNRLLSDSSRG +RVLGIMQRVHN-TKLLPAGLGKGAVIAHKTGTLGI-VLGDAGIIQMPSGKRYLAGIFVRR +PFNDL-KARDFINQVSRMVYG-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas trueperi TaxID=53317 RepID=A0A543M1U1_9SPHN +--ALLNAVQALGAGFQGQVAISVRDVDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID +HKRLSLATPVTVTRADLTVHQPIRPLVGPSGTTVGALLECALTRSDNTCNDVLLWKVGGP +AAIRHMLKEKGVDGVEFGPGERELQARYLAEPYDGATANGVTLGLSLLAKDKLLSHASTE +RLSRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS +TRQPIPVRMRLMGDVTRAVIR-- +>[subseq from] Uncharacterized protein n=2 Tax=Alistipes sp. An116 TaxID=1965546 RepID=A0A1Y4U656_9BACT +--TLEQDLEQLAASLEARIGIAIR-TPDGETI--SRQDVPLPLLSVFKFPVALAVLDKAD +AEGTPLTTPVEVGPEWLDPYSPLRDSLPATGVTLGELLRYSTSLSDNIACDRLLEYVGGP +NAVEHYVEKAGIEGFRIAATERTMHLDPANQRINVARPSAVCALFARLLEGGLLTPEHEA +LLQRLLEGAVTGTDKLRAGLPEGAVLGHKTGLSDRTADNDAGYVVLPDGRHYCVTVLVTD +SPADDAKNAAVIAAISKRIYEHf +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Omnitrophica bacterium CG1_02_49_10 TaxID=1805289 RepID=A0A1J4VRZ7_9BACT +-------VKEVSSAFSGEAGIVVRDMKGGYEI-VIDGDKPFPSASLAKAPIMAAYLLAAE +EGRVCLDETIRLKGYHKVGGSGVLKGVKTGKFTVEQLMELMITKSDNAATNMLIERL-GF +DYLNDAFKRLGLRNTNISRYMMDFKKR-SKGIENYTTANDVDLLLSDIYNGRLINKEVSD +RCMGLLKEQKM-ADRIPARLPPSTVVAHKTGLEK-GICHDAGIVFAPKGD-FAVTVLTRH +HNKDSRPSKKFISQIAFMVYTIy +>[subseq from] Beta-lactamase class A n=1 Tax=Gloeocapsa sp. PCC 73106 TaxID=102232 RepID=L8LQ12_9CHRO +--SLNQKIRDLTAKYQLDARAFFIDLDNYAYV-NFQGDTPISAASTIKIPILVAFFQDVD +AGKIYLDELLTMEEKHRAGGSGEMQYLGSGRFTALKIALNMIVTSDNTATNMLIERLGGA +EALNQRFQAWGLKSTVIRDILPDLEGK------NTTSPQDLVFLLGEVNAGKLISLRSRD +RLLDIMTATKN-NSLIPQGLEGDATVAHKTGDIGS-VLADGGIIDIPSGKRYLAAIMVKR +PHND-PQARTLIQEISRTAYQHf +>[subseq from] Beta-lactamase class A-like protein n=1 Tax=Bacillus firmus TaxID=1399 RepID=A0A380XTL2_BACFI +--SLQDRLEEVLRDASGTFGVYVKHLETGETA-AINENRFFQAASVFKIPILAALYRDVH +LGKVNLQERIRLEEADLVNGSGIFKELIPGIVTIKNLATMMVIVSDNVGTDKILRII-GK +ENVNQYMKEVGLNNTYIRFSCWELLCFQESIDNNVTTAFDMALLLEKIANKQLISEKACD +DMFEILEKQQF-RNRIPYLLPATTVVAHKTGTVAS-VVNDAGIVELPDNGRFIISAFSIG +NK-SEAEGARKIAELSRAAYGYf +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A3B9B5H0_9SPHN +---LESRIAQLADGSNGRIGVYAVDLTSGREI-GVLADQRFPLASTSKVAIAATYLAGVD +EGRWSLTSEYRLPR-------------PGGAMPAYRHLSLMISKSCNDCTDALLNAVGGP +SAVNKWMRGAGIEGFELTRNIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSEHSRR +VLLDAMLETTTGKRRMRSVLPVSANLAHKTGTLAR-TASDIGIFLTPDGRAIAAAIYVTG +QSPSMA----------------- +>[subseq from] Beta-lactamase n=2 Tax=Erythrobacteraceae TaxID=335929 RepID=A0A2D9PA32_9SPHN +---LESRIAQLADGSNGRIGVYAVDLTSGREI-GVLADQRFPLASTSKVAIAATYLAGVD +EGRWSLTSEYRLPR-------------PGGAMPAYRHLSLMISKSCNDCTDALLNAVGGP +SAVNKWMRGAGIEGFELTRNIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSEHSRR +VLLDAMLETTTGKRRMRSVLPVSANLAHKTGTLAR-TASDIGIFLTPDGRAIAAAIYVTG +QSPSMA----------------- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. SAORIC-644 TaxID=1869314 RepID=A0A2K1EB22_9SPHN +---LESRIAQLADGSNGRIGVYAVDLTSGREI-GVLADQRFPLASTSKVAIAATYLAGVD +EGRWSLTSEYRLPR-------------PGGAMPAYRHLSLMISKSCNDCTDALLNAVGGP +SAVNKWMRGAGIEGFELTRNIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSEHSRR +VLLDAMLETTTGKRRMRSVLPVSANLAHKTGTLAR-TASDIGIFLTPDGRAIAAAIYVTG +QSPSMA----------------- +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonadales TaxID=204457 RepID=A0A2D9XBS1_9SPHN +---LESRIAQLADGSNGRIGVYAVDLTSGREI-GVLADQRFPLASTSKVAIAATYLAGVD +EGRWSLTSEYRLPR-------------PGGAMPAYRHLSLMISKSCNDCTDALLNAVGGP +SAVNKWMRGAGIEGFELTRNIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSEHSRR +VLLDAMLETTTGKRRMRSVLPVSANLAHKTGTLAR-TASDIGIFLTPDGRAIAAAIYVTG +QSPSMA----------------- +>[subseq from] Putative beta-lactamase n=1 Tax=Parabacteroides sp. D13 TaxID=563193 RepID=C7X4B2_9BACT +---IENTLQEYIAGKDARIGVAVI-INSKDTV-SINGNRDFPMMSVVKFPLALTVAHWID +NNDMSLNDSIAFGENDLNEYSPMLKMYGKSRMTVRELFEWSLVESDNNAADILLKRIGGT +SGATSLMRQLNISEILIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYIEMRNTSRSYS +EISSMLEQCSTGRDRLAVLLPTNATIGHKTGTGFISAVNDCGYVKLPDGTRYSIAVFVAD +SGYDMGATSAIIAEISNIVWK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides sartorii TaxID=671267 RepID=A0A4V3RT29_9BACE +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRMTIRELLEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGALEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS +EISVMLEQCRTGLDRLALLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSVAVFVAD +SNYDIATTSAIIAEVSKIVLE-- +>[subseq from] Beta-lactamase n=1 Tax=Thermoanaerobacterium xylanolyticum (strain ATCC 49914 / DSM 7097 / LX-11) TaxID=858215 RepID=F6BKP3_THEXL +--SLHDDIMNFVSNAGGDIGVSVKNLKTGEMI-GVNEEMMFPSASTIKILIMAQIYKMAK +EGYIRLTDNIVLSDFMKTAGSGVLYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM +KNINKMAEDLGLFHTKIQRKMMDFE-AIKSGKDNYTCPKDMTRLLEQMYSGKVVDEEYSI +KMIEILKKQQD-LGRLDMYLPDDVLIAHKPGELKS-LEHDVGIVFLKDCD-YIISVMTNN +MNT-NLDGKMAIGKISKMVYDEy +>[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI001445C7A2 +--ELQTPIKTLMARYKLSPGIFFMDLETGDYL-SINGDKSFAAASTIKYPILIALFQQVD +AGEIQLDETLVMGRKHIVGGSGNMQYKVGSKFSLLETATRMMTISDNTATNMIIDRLGGI +TQLNQKFRSWGLENTVMRNRLGDFKGT------NKTSAKDLVKLSALMENNQLVSNTSEL +QVIGIMNGCRN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETSSGKRYLAGIFVRR +PNHD-ARAKDFIRQVSQVVYGYf +>[subseq from] class A beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=UPI000708D1E0 +-kTIEKALLEYVSDKDARIGIAVI-VNGTDTV-SVNGKRDFPMMSVVKFPLALTVVQWID +ANGLSLNDSIAFSEKALKEYSPMLKRYGKKRMTIRELLEWSLVESDNNAADILLNHVGGI +SGATKIMRKIGVDNIEIGASEDDMHRDPYLSYLNRTTPLAMAQLFDRFDTEMRNTSLSYS +EIATMLEQCRTGIDRLVALLSSDATIGHKTGTGFISAINDCGYVNLPNGERYSIAVFVAD +SGYDMAETSAIIAEISRIVW--- +>[subseq from] Serine hydrolase n=3 Tax=Clostridiales TaxID=186802 RepID=A0A413JG06_CLOSY +-eELKNRINEFIESQTGNICVSLFDLKEQDGF-SIDGDRRVPSASMIKLVIMAELMRRVC +AGELSLEEKIKITQEMRTGGDGVLKEEPGHEFSLREILTLMIIVSDNEATNILIQML-GM +DRINRMAAELGLKEAVLGRKMMDSEA-KKQGRDNFICADDIMLILKKIYEGSCVDRKASA +LMLDILKRQQQ-SGRLQLYLPEDVEVAHKCGDLDF-LENDGGIILLPGH-PYILAVLTNG +VK-TNKDGREAIGRISQIIYEE- +>[subseq from] Serine hydrolase n=2 Tax=Okeania TaxID=1458928 RepID=A0A6B3P403_9CYAN +--ALKTELDTVIAEYKLTPGIFLIDVDTGAYL-DINGNVAIAAASTIKVPILVAFFQAVD +QGRIKLDDMLTMEESHVAEGSGDMQRRPGTKYTALQTATKMIVISDNTATNMLIETLGGS +EVLNQLFQSWGLKNTTINDSLPDLSGT------NTTTPKDLINLISQVNQGGLVSLKSRD +RLFRIMERTKN-DSLLPRGIGRGTIIAHKTGNLKS-VLADVGMIDLLNGKRYLLAVLVKR +LD-DEQTAVDLIRDVSKKTYQY- +>[subseq from] Serine hydrolase n=1 Tax=Merismopedia glauca CCAP 1448/3 TaxID=1296344 RepID=A0A2T1C189_9CYAN +---VNAEIRSLMNRYKLSAGMFFVDLQTGEYI-DINGDRAFSAASTIKFPILMALFQEIE +AGRVSLSEPLVMRRGLMVGGSGNMSNKPAGTFTVSDTVNKMMIISDNTATNMIIERLGGK +NVLNQRFRSWGLQSTVIRNWLVDEKG------TNTTSAKDLVQLSALLANNKLVSDRSRL +MVMDIMRQCHN-RSMLPAGLGSGAVIAHKTGTLRF-VLGDAGIIQTPSGKTYLAGIMVRR +PNHD-RRATSFIRQVSQLVYNY- +>[subseq from] serine hydrolase n=1 Tax=Sphingobium baderi TaxID=1332080 RepID=UPI000688F693 +--DLLNAVQGLGSAYKGKVGISVRDIDEGWTV-SFNGDASLPQQSVSKLWVAIAVMDAVD +RGKLKLSDPVTVRRSDLTVHQPIRPLVTKSGTTIGKLLELAMTRSANSCNDVLLWKVGGP +SAVRTMLARKGVSGVGFGPGERVLQARYLAAPYDGASPNGITLGLAMLKRGELLTPASTR +HLLSLMRASRTGPLRLRSGLRSGWTLAHKTGTGQSTGYNDVGILNSPDGHRYAVSVMIAS +TRQPIPVRMRLMGDVTRAIIR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Stigmatella aurantiaca TaxID=41 RepID=A0A1H7L6F0_STIAU +--------QRIAQVKGASVAVAYLNLGDSRDTvFLGAEASFHAASTMKVPVMIEFFRQVD +AGKLSLDQPVPLANRSIVDGSPYTYERLGQAVPASELLKRMVTRSSNLATNTLIARV-DA +KRVTRTLRALGARSMTVLRGVEDAK-AYAKGLNNTATARDLATLLAALEQGKAASPRSTQ +AMRDILLAQEL-NTLIPAGLPPGTPVAHKTGQIT-GVLHDAAIVYPPGRAPYVLVVLTRD +IP-EAPVAEALIADLARQVHA-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8W4M3_9BACT +-eKLEATINGVDRNLEGVLGVAILDLTTGQKY-FLHADEVLPTASSIKIAVLAELYRQAQ +QGKIKLGDLYTLQSSDLAGGSGIAGALTPGVLTIRDVAVLMISVSDNSATNIIIDRI-GI +ENVNALLDSLSLTQTRLRRKMMDVKAA-GEGRENIATPREMVTLLESLYRGRVLNKPMTE +DFFTLLSVHKE--SYIPRELPEDLRIANKPGELE-GVRNDSGIVFTGSR-PFAISVMTTY +LRRE-KDGGDAIVRIATAAYQMf +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WY31_9BACT +--SLAELISSIQVKSGGKVAVSVRHIETNQGG-SWRGFEEMPLYSVFKLPLAVVVLKDVE +AGKLQLDQRVSVKESDVAPIAANTDRNVPLEMTVRQLLELSLIESDNTSSDKLLQLTGGP +GALTKRIESLGFDKIKINVSVKEMSQN--KKHLNVATAESIVRLLSGLQQGSVLKDEQRT +VLFELMGKSRTGLKRLRGLLPAGTAVLDKTGTGPDGAINDVGIVTLPSGGHLAVAVLISG +SKLPVEEQEHMIAEIALASYKLf +>[subseq from] Beta-lactamase n=2 Tax=Clostridiales TaxID=186802 RepID=E7GH01_CLOSY +-eNLKNRINEFIESQTGNICVSLFDLKEQDGF-SIDGDRRVPSASMIKLVIMAELMRRVG +AGELSLEEKIKITQEMRTGGDGVLKEEPGHEFSLREILTLMIIVSDNEATNILIQML-GM +DRINRMAAELGLKEAVLGRKMMDSEA-KKQGRDNFICADDIMLILKKIYEGSCVDRKASA +LMLDILKRQQQ-SGRLQLYLPEDVEVAHKCGDLDF-LENDGGIILLPGH-PYILAVLTNG +VK-TNKDGREAIGRISQIIYEE- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf9 TaxID=1735674 RepID=A0A0Q4CU02_9SPHN +--DLLNAVQALGAGFEGQVGISVRDIDENWVV-DWQGDTPRPQQSVSKLWVAIGVMDAVD +QGRLSLADPVIVTRADLTLHQPIRTLVGKTGTTVGNLLRGAMSRSDNTANDVLLWRIGGP +AAVNRMLKDKGVAGVCFGPGERQLQARYLDAPLDGASANGVTLGLSLLAQGRLLSDRSTA +SLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS +TRQPIPARMRLMGDVTRAVIA-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. CAG:462 TaxID=1262740 RepID=R7CZR4_9BACE +---LREEVGAFLRDKRATVGVSVL-TDSTTLL-AWNDTLHLPLLSVFKFPVALAVLHRME +QQQTPLDTVLHLTPDDLKTYSPLCIRYPERSIRMDSLLYYSVALSDNNACDVLLRYAGGP +RAVEQYIHQLGITDVRLSATEDDMHRQPGRVSDNSATPEAISRLFRLFLQEGLSAPVYRN +YLYRVLTSTSTGMNKLPAGLPDHAILGHKTGSSDKTADNDAGFVLLPDGQRYYITVLVTN +SLENDSVNAAIIATLSHIVCRH- +>[subseq from] Serine hydrolase n=1 Tax=Scytonema hofmannii PCC 7110 TaxID=128403 RepID=A0A139X861_9CYAN +--TLNSQIRALMERYSFLLGMFFLDLQTGDYL-NINGDKAFPAASTIKFPILIALFQEIE +AGRVRLDEPVVMRQDLVAGGSGMQSKSVGSRFTILQTATKMMTISDNTATNMIIDRLGGK +AVLNQRFHSWGLQNTTIRNLLADVNGT------NTTSAKDLVKLSALVTNNQLINDTSRS +QVLEMMRHCHN-QSMLPSGLGSGAIIAHKTGTLRF-VLGDAGIIQTPSGKIYLAGILVRR +PNHD-SRATEFIRRVSQFVYEY- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Sporomusa termitida TaxID=2377 RepID=A0A517DYG6_9FIRM +-eRLHTKIQTLLAQYSCRSAVIVRNESTGNAL-AINPAMVFPAASMIKIPIMIEVMRQAA +AGKLPLAKTVAITSQMQTGGAGILKEQPGIKMTVAELVTLMIILSDNTATNVLIDLA-GM +AAINAAITGLGLRSTVLQRKMMDFAAA-KAGRENLTSAADLARLFAGIAGSTAVPPPYNA +MMLDILKRQQI-RDKLPFYLPAEVIIAHKTGTLA-GAEHDGGILFAPGG-PYIICVLTAE +LTAN-YEGLQLVAMIGKIIYEY- +>[subseq from] serine hydrolase n=1 Tax=Runella zeae TaxID=94255 RepID=UPI0003FF81EF +---LRTSIVSKLGQIEGDFAVAFKDLQTQQTL-FINEKENFHAASTMKTPVMMEVFRQAQ +AGKFNLSDSILVKNESIVDGSPFKYKKIGSKMTIYDLTYQMMIVSSNLATNILIDLV-DA +KKANQFMRELGAKDINVLRGVEDTK-AFEKGLSNTTTAYDLMLIFEKIAQKKVVSPTASD +KMIQILLDQKF-NEIIPAQLPSNVRVAHKTGSIT-GVRHDSGIVYLPNGKAYVLVLLSKK +LTN-PEAGVKAMAEVSEMIYN-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A166NHH3_PSEAI +------------------------------------------------------------ +--------------------------------------------------DKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAA------- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Omnitrophica bacterium TaxID=2035772 RepID=A0A358AGR3_9BACT +-dNLKKEIEGRIADFRGNIGIVIKDLNEGWEI-DFNKGALFPSASLVKVPILLSYFYAQQ +EGKVRTSDLVSLKSYEKVPGSKVLGDSSVGSFSVEELFEPMIAKSDNTATNILIDLL-GF +EAFNDYFIRLGLRNTNLVRRMMDFEER-KEGRENYTTAEDMAYLLEILYRRSFLDKNTSE +KCLGFLKQQKI-KDRIPRKLPEGVTVAHKTGLENY-ICHDAGIVFTQKGD-FLICVLTKH +QDKFAAPAKRFISDIALITYNYy +>[subseq from] Serine hydrolase n=2 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=A0A1E4R8W0_9BACI +---LQESLEKVIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILVTLYRDVQ +MGKVELKERIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLNML-GK +ENVNQYMKEIGLSNTYINLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH +DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDSGNFIISVFSIG +NI-TEAEGASIISKLSRVAYNHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F1DI07_KLEPN +-------------------GMIEMDLDSGRTLtAWCSDERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSENSATNLLLATVGGP +AGLTAFLRQIGENVTRLDRWETELNEALPGDSRDTTTPA--------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896) TaxID=504472 RepID=D2QDV0_SPILD +--KLRQQIEQELSRHPGTFAVAFKDLKTGKEL-LIREHEVFHAASTMKTPVMIEVYKQAA +QHKLALSDSMTITTDSIVDGSSYSYKAVGTKRTLAALVYDMIIVSSNLATNMVIERV-GA +QNVTQTMRDLGAKDIQVRRGVEDSKA-FAQGLNNTTTAYDLMVIFEKIARGKAVSPDASK +AMITTLLDQKF-NDAIPGKLPKDVKVAHKTGSIT-GVRHDSGIVFLPDGRKYVLVLLSKE +IK-DDKETIETMATVSQWIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Euhalothece natronophila Z-M001 TaxID=522448 RepID=A0A5B8NR54_9CHRO +--DLKQTFERLGSEQQLNPTAFIIDVDSGEYV-DLQGNTTVSAASTIKLPILIAFFYAWE +QGELELDERLTMTEDVKVGEAGRMQDDVGTEYVALETATEMIRISDNTATNMIMKRVGGK +EVLNQLFAQWGLEKTRIRDQLPDVEGT------NTTSPKEMVELLVKLEKGELLSARSRD +KVFEILQTTET-DSLLPQGLGDGATIAHKTGHIGS-VVGDVGIINRPNGQRYFAAILVER +PHND-SHANELIRNYSQHTYQYf +>[subseq from] Serine hydrolase n=1 Tax=Nostoc minutum NIES-26 TaxID=1844469 RepID=A0A367Q8R0_9NOSO +--QLSSQVKGLMARYSLEPGMFFLDLDTGNYL-DFNGEKAFPAASTIKFPVLVALFQEVD +AGRVKLNESLVMRRELMTGGSGVIQKRPGTRFSLLDTATKMITISDNTATNMIIDRLGGK +AKLNQRFRNWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLSALIVNNQVLSNSSRS +QVLSLMRRVEN-RSLLPSGLGKGAVIAHKTGTLGV-ILGDAGIIEMPSGKRYLAGIMVRR +PFND-LRGKAFISQVSRLVYSY- +>[subseq from] class A beta-lactamase n=1 Tax=Bacteroides barnesiae TaxID=376804 RepID=UPI00037C980F +--SLRQELANRIKNCRAQVGVALV-VDGKDTL-TLFNEVPYPLMSVYKLHQAMAVGKYLH +ERGRTSESRIAIGKEDLKPYSPLRDKYPDGNLSVRELLEYTLQWSDNNACDILFAHTGGT +AGTDRYIRSLGLKEFAISSTEDEMHRDLDKCYDNWSSPLEMARLLEILFTTDLEMGEFQP +LIRQILMTCRTGLNRLPKPLENGAQIAHKTGTGDKNGINDAGMVFLPDGRRYTLVVFVKD +SWESMEKTEQLIADVSEIVYRY- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536FCW5_9CHLR +-----RRIEEIGSGV-GIVGVAATRLSDGRHI-GIREDELFPTASVFKVPLLVALYAEAL +AGRLDLGERVGYRADTRVAGSGVLQFLDDGLPTLRDLAVLMMTVSDNTATDLVLERV-TK +DRVNATMREYGLRSIAVPFGTREMLMSIVPAETDRTTPREMCRLLELLATDAILDAGSCR +AILEIMERIQS-GTRLPGLLPKGTVVAHKTGSLRR-TRNDVGIVRAPNGA-YAVAIFTRE +LVRDNVDDERAIAAMSLAVYE-- +>[subseq from] serine hydrolase n=1 Tax=Planococcus sp. CAU13 TaxID=1541197 RepID=UPI00053001D1 +--QLQQQIEQYISGIDAEFGISIKHLKTQEEV-NIQGDRLFQMASVVKVPILATLYDLAE +KGEIDLNQRIEMLDEDHVPGSGVFKAMDSGIPTIKDLATMMIIVSDNQATDKLLELVGGA +EAVEEKMKSIGLNNIHIKHSIWDLLSFQESPESNTSTAKDMTLLMEKIAMGEFVSKECSA +AIYEILLKQHY-QQRIGGSLPRNTKVANKTGSLGT-MFNDTGIVQLPDKGAFVITVYSIG +SSLD-YKGDEPIAEISRMAYE-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Omnitrophica bacterium TaxID=2035772 RepID=A0A3B9ZHF9_9BACT +-qALERALSQEVSRFQGEAGVILKDLDMDWQI-AVNKTKSFPSASLAKIPIMASCFYAVF +QGKIKLQDELILKERHKVLGSGTLKTMAAGRVSIENLIERMITESDNTATNMLIELL-GY +EYMNSCFKEFGLKDTSLARKMMEFKLR-RKGVENYTTAGDVALLLEKMYRKEVINAEFSE +RCLSLLKQQKI-KDRIPALLPPEVVIAHKTGLERH-VCHDAGIVFSPGGN-FLLCVLTSH +TDKTSKRAKEFIARLAFEAYRYf +>[subseq from] Serine hydrolase n=1 Tax=bacterium TaxID=1869227 RepID=A0A522P938_9BACT +--QLQSHLDSLARHAPGDVAVAVRDLRTGEVV-GYNAHASLPAASTIKVPVMVEVFRQME +AGAFTLDRDVTLASADRDGWGDLADAPAGSHYTVRRLLWLMITQSDNTAANMLIRLV-GR +AHVNQTMHALGLGNTSLSDYIRSYGDI----RSIRTTASDMVRLMAMIAHGTLVDEWSCG +EMLEIMAGQQI-NTLLPQPLPADVLVAHKTGSLHD-TLNDVGVVYLA-GAPYAIAVMTTH +LA-SLDSGRAFIHAVSSLTFK-- +>[subseq from] Serine hydrolase n=1 Tax=Parabacteroides distasonis TaxID=823 RepID=A0A3L7ZL56_9BACT +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSLMTVRELLEWSLVESDNNAADILLHRIGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS +EISVMLEQCRTGLDRLALLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSVAVFVAD +SNYDIATTSAIIAEVSKIVLE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A2Z6A9G4_SHIFL +------------------------------------------------------------ +------------------------QKSIGRMASQEEDCSADITMSDNTAANLVLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLNSALPAGWFIADKSGAGERGWRGINAALGPDGMPSRIVVIYTTG +KQATMDERNRQIPEIGASL---- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. ZX TaxID=2606412 RepID=A0A5D9C947_9SPHN +--ALDRRIEALGSGFRGDVGLAVRDIQTGWIS-HYRGLDYFPQQSVSKLWVAISAFDMAD +RGKLDLRGRLSVRPNDLTLHQPIRSLATRPGTDREDLLTRALTQSDNSANDKMLREVGGP +DAVRATLAAKSISGIRFGPGEKGLQSAYVADPVDGARPIAMVDALARLKTGELLSDASTA +QMLDLMGQTRTGALRLKSGLRPGWTLSHKTGTGQQAGYNDVGILTSPEGRSYAVAVMIGR +TSRPLPERMDLMRKVVRLTIA-- +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus telephonicus TaxID=1714840 RepID=A0A3S0QXT4_9BACI +----KEKVQRLIEEVRFDVKVVVSEANSNEFLiGIGIDDVFQSASLIKVPIMLAVLDYVE +DNNVSLKQVIAIKEENVVDFSMITEQGLK-NSTIYDLLVGMIITSDNTATNVLIDFI-GM +DNLNQYFKKIGLTQTILNRKMMDFEQV-KKGLDNVTTARDMSVLFRHIYRQDLLTPKNCE +LALNILKRQRI-YESLKRYLVDDVTIAHKTGSLDT-VEHDVGIVFSPLKD-YMIGIFVTN +HC-DNEEAKRLIGRISKVVYQHf +>[subseq from] Serine hydrolase n=3 Tax=Nostocaceae TaxID=1162 RepID=A0A1W5CH86_9NOST +--QLDSQIKQLMNRYSLSAGMFFLDMETGEYL-DINGEKTFAAASTIKFPILIALFEEID +AGRINPNETLVMRRDLMTGGSGTMQYRKAGSFKLMETASKMMIISDNTATNMIIDRLGGK +NRLNQRFRSWGLQNTVIRNLLGDFKGT------NKTSPKDLVRLAALISNNKLLSATSNS +RVMDIMSRCKN-RSLLPVGLGKGAVIAHKTGTLGR-VLGDAGIIQTPSGKRYLAGIMVAR +PFGD-ARAKAFINQVSRLVYG-- +>[subseq from] Class A beta-lactamase n=3 Tax=Bacteroidales TaxID=171549 RepID=A0A4V6RE54_9BACT +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSLMTVRELLEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS +EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSVAVFVAD +SNYDIATTSAIIAEVSKIVLE-- +>[subseq from] serine hydrolase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI0009EB1A4D +--DLLNAVQALGAGFEGQVGISVRDIDENWVV-DWQGDTPRPQQSVSKLWVAIGVMDAVD +QGRLSLADPVIVTRADLTLHQPIRTLVGKTGTTVGNLLRGAMSRSDNTANDVLLWRIGGP +AAVNRMLKDKGVAGVCFGPGERQLQARYLDAPLDGASANGVTLGLSLLAQGRLLSDRSTA +SLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS +TRQPIPARMRLMGDVTRAVIA-- +>[subseq from] Beta-lactamase n=2 Tax=Gemmatirosa kalamazoonesis TaxID=861299 RepID=W0RCA7_9BACT +--RMEDSVRAIAERTDAVVGVAILDLTDGRAL-YLNADAAYPTASTIKIALLAELYRQDE +RDGAKLGDTYTVDAKDAVGGAGIMGGLSPGALTNRDLARLMVSLSDNSATNVLIDRV-GM +ERVNALLSGLGLEKTRLRRHMMDTRAA-REGRENTATPRELVTLLGALHAGRVLGRVATD +SFFAMLSTGKN--GYITRLLPPDVTVANKPGDLD-GVRNDAAVVFVPGR-PFAIAVLTTY +GG-DDRAAEGRIAEIARAAWTYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V5A8_9BACT +------------------------------------------------VMAVSALLKQSE +TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLGEFSAATIQYSDNTAMNKILEHLGGP +AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA +QLVEWMKGNTTGGASIRAGLPTT------------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=unclassified Lysinibacillus TaxID=2636778 RepID=UPI000B7C64A2 +---LQESLEKIIQEATGTFGVYVKHLESRETA-AINENRLFQAASVFKIPILATLYRDVQ +MGKVELKEHIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK +ENVNQYMKEIGLSNTYIRLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH +DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGNFIISVFSIG +NN-TEAEGASIISKLSRVAYNHf +>[subseq from] Beta-lactamase n=1 Tax=Fusobacterium nucleatum CTI-5 TaxID=1316586 RepID=U7T4W2_FUSNU +-tEWKKEIEKIISRVKGSVCINFYDLAKNNGF-SINGDKKVLSASMIKLLILAELMKKVS +ENKFSLSDAITVTEAMKTGGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINQLGRELDLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQEKLINKKASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIENKA-YILVVLTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] serine hydrolase n=1 Tax=Pseudonocardia acaciae TaxID=551276 RepID=UPI0009FFDE6B +-----DELAARATKLGGALGAVIEDLRTGRRA-EVGAQRAFTSASVIKLPIAMTVLA--- +-GELPLDRQVMVRAAARAGGSGILRDLEVPALSVRDLLTLMITISDNTATNVLIDLV-GI +DAVNAWCAGHGLTGTVLARRMFDAEAR-ARGEENLTTARDVATLLADLARGRLLDPPATD +FALDVLARQRV-NDRLPRHLPDGLRLAHKTGELD-GIRHDAGIVLDKGK-PTIVVVALTE +AINSAATACDLIAEVGRLAY--- +>[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI001447BAC8 +--ELQTPIKTLMARYKLSPGIFFMDLETGDYL-SINGDKSFAAASTIKYPILIALFQQVD +AGEIQLDETLVMGRKHIVGGSGNMQYKVGSKFSLLETATRMMTISDNTATNMIIDRLGGI +TQLNQKFRSWGLENTVMRNRLGDFNGT------NKTSAKDLVKLSALMENNQLVSNTSEL +QVIGIMNGCHN-KSLLTSGLGSGAKIAHKTGTLRF-VLGDAGIIETSSGKRYLAGVFVQR +PNND-SRGTDFIRQVSQVVYGYf +>[subseq from] Beta-lactamase (Fragment) n=4 Tax=Enterobacteriaceae TaxID=543 RepID=A0A125SIY0_ECOLX +---------------------------------------------------CGAMLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDR-------------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D4Y5D5_9SPHN +---LESRIAQLADGSNGRIGVYAVDLTSGREI-GVLADQRFPLASTSKVAIAATYLAGVD +EGRWSLTSEYRLPR-------------PGGAMPAYRHLSLMISKSCNDCTDALLNAVGGP +SAVNKWMRGAGIEGFELTRNIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSEHSRR +VLLDAMLETTTGKRRMRSVLPVSANLAHKTGTLAR-TASDIGIFLTPDGRAIAAAIYVTG +QSPSMA----------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Atelocyanobacterium thalassa isolate SIO64986 TaxID=1527444 RepID=A0A086CHW6_9CHRO +----KKQLEDINIKYDVQPKAWFFDLDTNTYV-NFNGTKSISAASTIKIPVLIAFFEKVD +AGDISLDQMITMDKEMIVSGSGNMQYMQAGKFTALEIARKMIIISDNTATELLVRQIGGK +FFLNERFKKWGMKQTVINNPLPDLNGT------NRTSPEDLTKLLLRIERGDLISLRSRD +RFLNIMRETKT-KTLLPKGLEKNASIAHKTGDIGT-IIADAGIIDMPTGKRYIGSIFVER +SY-DDPAGRELIQKFSKAIYQY- +>[subseq from] FRAMP1.1 beta-lactamase n=1 Tax=Prevotella sp. CAG:1185 TaxID=1262921 RepID=R5MI05_9BACT +-----KAVESLIKGKDAEIGVAWME--GNAMY-SVNNERLYPLMSVCKLHVAIALLRGME +RRGAAVDTTLNITPEQMRKYSPLLKLHPDGRITLRQLIHYAIAESDNNAADILTAMAGGI +DSVDREIHAMDIKGCHLAETEASMHDAPINSYANWSKPESVVWLLRKLYDGRLLSGEYDR +CIKQALAATTTGADRIKAGLGQGMTLAHKTGTGFKTADNDAGVVTTSDGRQVIMAIMIKD +SKMSDADNARLMAEITRIIM--- +>[subseq from] Beta-lactamase class A n=1 Tax=Thermoanaerobacterium thermosaccharolyticum M0795 TaxID=698948 RepID=L0IPB7_THETR +---LYDDIKRFVTSTDGNIGVSIKNLKTGERI-DVNEEMMFPSASTIKILIMAQIYKMAK +EGYIRLTDNIVLSDFMKTAGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM +KNINRMAEDLGMLHTKIQRKMMDFEAA-ESGKDNYTCAKDMTHLLELIYAGKVVDKEYSN +MMLNILKKQQD-LGRLDLYLPEDVLIAHKPGELKL-LEHDVGIVFLKNCQ-YIISVMTNN +LSTN-LDGRKAIGKISKMVYDEy +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas astaxanthinifaciens TaxID=407019 RepID=UPI0004A733EA +------------------------------------------------------------ +--------------------------------SARGLLEAMLIHSNNVATDHLINNLGGP +TAVQSWLTFNNVRGVRVDRTIARLLADKRWDLRDSATPLAMVQLLRTIDRGNVLSQSSHR +YLLSVMARCQTGKNRIRGMLS-GVPIEHKTGTLNN-YASDVGFITMPDGRRLAIAIFARG +GT----DRPTTIAQTARTIYDGf +>[subseq from] serine hydrolase n=1 Tax=Spirulina major TaxID=270636 RepID=UPI0009355AFF +------TLDAIAAQQDLQTSVFVVDLDTGDFV-NLNGTATMAAASTIKLPILIAVFQEVD +RGLVDLSEPLVMTTEMMASGSGTMQYTPGTTYSLEATAEKMITISDNTATNMLIQRLGSA +PLLNERFRDWGLKQTSIQNLLPDLTGT------NETSPLDLVTLLAMVHDGKLVSLRSRD +QLIRIMQQVEN-RDLLPQGLDEQAVIAHKTGDIGS-MLGDVGIVDTPMGKRYAIAALVGR +PHND-DRARILIQDLSRATYQHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V590_9BACT +------------------------------------------------FMVASAILKESE +VKKNLFTQHVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP +NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWIV---------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Thermoanaerobacterium sp. PSU-2 TaxID=1930849 RepID=A0A1X2FWX4_9FIRM +--SLHDDIMNFVSNAGGDIGVSVKNLKTGEMI-GVNEEMMFPSASTIKILIMAQIYKMAK +EGYIRLTDNIVLSDFMKTDGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM +KNINKMAEDLGLFHTKIQRKMMDFE-AIKSGKDNYTCPKDMTRLLEQMYSGKVVDEEYSI +KMIEILKKQQE-FGRLDLYLPDDVLIAHKPGELKS-LEHDVGIVFLKDCD-YIISVMTNN +MNTN-LDGRMAIGKISKMVYDEy +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas azotifigens TaxID=330920 RepID=UPI000A03EE7A +----VNRLSDIARNFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD +QGRIRLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP +PAVRSFIARNALGSIRFGPGEKLLQLSYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ +WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD +TPRPINERQLLMQGVVRAIVA-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudanabaena sp. TaxID=1153 RepID=A0A352JFG1_9CYAN +-----NKIKELAKEKDLSMQMMMVDLDSGVYV-QIGANQPITAASTIKTPVLVAFFQDVD +AGKIKLDEPLEITSDVKVGEAGDFQFLPGTKISAITTATQMIVISDNTATNMIIKRLGGF +TALNQRFKSWGLSNVVINNPLPDLEGT------NTISTQDMVTLLAMIDKGKLIEPRSRD +RFMDIMRRPIT-NTLLPKGIDEEARIVHKTGDIRS-AVGDAGIVDMPNGKRYAIAVMVKR +PDND-QRANELIRQISRATYDYf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas azotifigens TaxID=330920 RepID=UPI001430FF3A +----VNRLSDIARNFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD +QGRIRLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP +PAVRSFIARNALGSIRFGPGEKLLQLSYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ +WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD +TPRPINERQLLMQGVVRAIVA-- +>[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. 5-2 TaxID=1926885 RepID=A0A2P4UNU4_9ACTN +--KALDELAHRAEGRGGVLGVVVQS-ANGEYA-SVNADRAFTAASLIKLPVMLALLDGVE +AGRWSLDDRLPVR--DRVGGAGILRDLADVALSVRDLVTLMIVISDNTAANLLIDRI-GA +PAVADWCGRHGLRATVLERRMMDAEAR-ARGAENRTSPADMAKLLDGLVRGTLLGPAMTA +FALDVLARQQV-RDRLPRYLPAGLRIAHKTGELD-GLRHDVGIIFTN--APIIVAALTEN +AD----EADDLIAESARRAVQ-- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Muribaculaceae TaxID=2006847 RepID=A0A3N2K5X7_9BACT +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSLMTVRELLEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS +EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFEGAVNDCGYVNLPNGTRYSVAVFVAD +SNYDIATTSAIIAEVSKIVLE-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TKS TaxID=1315974 RepID=A0A126RVL4_9SPHN +--DLLNAVQGLGSAYKGKVGISVRDIDEGWTV-SFNGDASLPQQSVSKLWVAIAVMDAVD +RGKLKLSDPVTVRRSDLTVHQPIRPLVTKSGTTIGKLLELAMTRSANSCNDVLLWKVGGP +SAIRTMLARKGVSGVGFGPGERLLQARYLAAPYDGASPNGITLGLAMLKRGELLTPASTR +HLLSLMRASRTGPLRLRSGLRSGWTLAHKTGTGQSTGYNDVGILNSPDGHRYAVSVMIAS +TRQPIPVRMRLMGDVTRAIIR-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V5A3_9BACT +------------------------------------------------FMAASAILKESE +VKKNLLTQHVALRKSDRVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP +NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWIV---------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Paucisalibacillus sp. EB02 TaxID=1347087 RepID=UPI0012DE4269 +-rELSERISQITEDASGTWGISLHDLDTDEKW-ELNAHELFYSASVIKIPIMITVFASSH +RNQFSLSNCLTLKREDLVGGSGVLQHMTPGTISIYDLIMLMIIQSDNTATNMLIDLV-GT +EAIQQTMKNIGLEKSNFYHKMMTIDV--EREGLNEITAHDMTNMLKKILTGKIISAHACE +QMIDILKKQQV-RNSLPAKVPKQWEIANKTGNVS-GIRHDVGIFYVGKR-TFIASVLTRG +LD--DLQSPEIIGRVGLEIYQY- +>[subseq from] Beta-lactamase class A n=2 Tax=Bacillus simplex TaxID=1478 RepID=A0A1N7GKE6_9BACI +---LQDRLEEVIQDATGTFGVYVKHLESGETA-AINENRFFQAASVFKIPILAALYRDVE +IGKVRLQERIRLEEVDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLNIL-GK +ENVNQFMKEVGLNNTYIRFSCWELLCFKESIANNVTTASDMALLLERIAYKQLISEKACD +DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGRFIITAFSIG +NK-TEAEGAGIISELARVAYNHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9QD60_9BACT +-dKLESQIREIDRNLDGVMGVAIEDLTTGQKF-FLHEDEVFPQASSIKIAVLAELYHQAQ +SGKARLADLYTVEAKDMVQDSDIMLGLTPGVVTNRDLATMMVAVSDNSATNVLIDRL-GM +ENVNALLDSLGLTHTHLRRKMMDVKAA-SEGRENVSTPREMMTLLEQVYRGKILNKEMTD +DFLKMLATHKG--SAISRDLPEGVRSADKPGELE-GVRTDSGIVFAENR-PYVISVMTTY +LHN-EHDGAEAIARISVAAYGMf +>[subseq from] serine hydrolase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI001196401A +--ELQDRLEEVILDATGTFGVYVKHLESGETA-AINENRFFQAASVFKIPILAALYRDVE +IGKVRLQERIRLEEVDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLNIV-GK +ENVNQFMKEVGLNNTYIRFSCWELLCFKESIANNVTTASDMALLLERIANKQLISEKACD +DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGRFIITAFSIG +NK-TEAEGAGIISELARVAYNHf +>[subseq from] Serine hydrolase n=1 Tax=Rhodoferax koreense TaxID=1842727 RepID=A0A1P8JQ59_9BURK +--RMQAEFTRIETQSGAGLGVYVRDLGTGHAA-SHRAEETWYLASTVKVPIAIAVLRGVD +RGDYRLDTRLVLRDTDLVDGAGQTKQHVGAPLSIRYLLNQMIVYSDNTASDMLIGLV-GI +DAVNAVVHELVPQGFQRITTLADVRRAYYATGLNSGRLDAYADLLELLARGKALSAGSTK +YLLGVMERVRTGPNRIKAGLPPRAHFAHKTGTQR-ARTCDSGVVTLPGRDQRVVVVACTS +GELSSTRSDHTLRQVGTALCK-- +>[subseq from] serine hydrolase n=1 Tax=Gudongella oleilytica TaxID=1582259 RepID=UPI000FF8972A +-------VMEMMKELKGNIGVYYKDLTTGESF-GIRADEKYLAASVIKLMVLLEAFKQES +QGKISFDQFIEIKEKDKLPCGSLTYMHDGLKVTIMDLCVLMIIQSDNTATNIMIKLL-GM +DSINSTIRELGFEKTKLNRLLFDSEEQ-KKGKENYISPLEMGTFLEKLYNGELISKKASM +AMLDIMKTQQL-NHKIPYYIPKGVKIAHKTGEDD-GITNDVALVFSE--RPFIICFAAYG +TNVQ--MTEDFYRKAAKLFYD-- +>[subseq from] Beta-lactamase n=2 Tax=Fibrisoma limi TaxID=663275 RepID=I2GJ30_9BACT +--SLTDSLTAYLRRLNAQVSVAVESLADSTRSfHHQADERVPSASLIKLPILIEAMERIK +AGQLDPDEIHILTDSEKTGGDGILKTYSHRSIAYRDIIRLMMIHSDNTATNILINEL-GM +NAINQRIRSLGLAKTQLNRVMMDTAA-VRQGRENYVTAREMNQLLTKIYQHQIATPALCD +QMLDILKQNEN-RQTIPRLLPNTVVVAHKTGILSY-VRGDVGIIYAP--QPFVLSVLVQG +VS--TAEAERIISEIALMCYNHy +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium chungbukense TaxID=56193 RepID=A0A0M3AKP9_9SPHN +--DLLNAVQGLGSAYKGKVGISVRDIDEGWTV-SFNGDASLPQQSVSKLWVAIAVMDAVD +RGKLKLSDPVTVRRSDLTVHQPIRPLVTKSGTTIGKLLELAMTRSANSCNDVLLWKVGGP +SAIRTMLARKGVSGVGFGPGERLLQARYLAAPYDGASPNGITLGLAMLKRGELLTPASTR +HLLSLMRASRTGPLRLRSGLRSGWTLAHKTGTGQSTGYNDVGILNSPDGHRYAVSVMIAS +TRQPIPVRMRLMGDVTRAIIR-- +>[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. TKS TaxID=1315974 RepID=UPI0009EB055D +--DLLNAVQGLGSAYKGKVGISVRDIDEGWTV-SFNGDASLPQQSVSKLWVAIAVMDAVD +RGKLKLSDPVTVRRSDLTVHQPIRPLVTKSGTTIGKLLELAMTRSANSCNDVLLWKVGGP +SAIRTMLARKGVSGVGFGPGERLLQARYLAAPYDGASPNGITLGLAMLKRGELLTPASTR +HLLSLMRASRTGPLRLRSGLRSGWTLAHKTGTGQSTGYNDVGILNSPDGHRYAVSVMIAS +TRQPIPVRMRLMGDVTRAIIR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. BK036 TaxID=2512122 RepID=A0A4Q7SGS5_9SPHN +--DLLNAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD +RGQMSLADPVTVTQSDLTVHQPIRALVGKDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP +AAINRMLATKGVAGVTFGPGERHLQARYLAAPIDGASSNGVTLGLSLLAQGKLLSPRSTT +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS +TRQPIPARMRLMGDLTRAVVA-- +>[subseq from] Uncharacterized protein n=1 Tax=Ignavibacteriales bacterium CG07_land_8_20_14_0_80_59_12 TaxID=1974045 RepID=A0A2M6YY62_9BACT +-dKLLAHLQSIVDTSDAVVGIAAKDLTSGEEF-FINENEIYPQASAIKIHILAELYRQAA +EKKFSLSEIRPLPESERVGGSGVLNELGRNTMSIRDYAVLMIVLSDNTATNVLIDLV-GM +DNVNKFLGGLGAQKTRLQRKMMDYKAA-AEGRENIGTPKEVLMVLEKMYLGEISGRAASE +DMLSIMRKPKPG--PIRSGVPATVDVANKEGEIE-GIRTDVAIVYLPGK-PYAICVMAKY +LLHD-EDGPRIITDVSSAVYSYf +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0009903361 +------------------------------------------------------------ +----------------MVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Serine hydrolase n=1 Tax=Calothrix sp. HK-06 TaxID=1137096 RepID=A0A1Q4S0B8_9CYAN +---LETQIKTLMNRYSLTPGIFFLDSQTGDYL-NINGEKIFPAASTIKYPVLIALFEEVD +AGRIRLNETMVMQRRHLAGGSGNMRFRPAGTFSLLETATRMMTISDNTATNMVIERLGGI +AKLNKRFRTWGLEQTAMRNMLGDFGGT------NRTSAKDLVRLSALVTNSNLLSDASRN +QVLNIMYRCQN-RRLLPSGLGKGANIAHKTGTLRF-VLGDAGIIQTASGRKYLAGILVRR +PHHS-PQARDFIRQVSQLVYNH- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. ABOLE TaxID=1985878 RepID=A0A430EPD8_9SPHN +----VNRLSDIAHDFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD +QGRIRLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP +PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ +WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD +TPRPINERQLLMQGVVRAVVAE- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. ABOLD TaxID=1985877 RepID=UPI000F7E4447 +----VNRLSDIAHDFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD +QGRIRLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP +PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ +WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD +TPRPINERQLLMQGVVRAVVAE- +>[subseq from] Beta-lactamase class A n=1 Tax=Rivularia sp. PCC 7116 TaxID=373994 RepID=K9RI85_9CYAN +--QLHSQVKSLMSRYSLDPGIFFMDLETGDYL-DINGEKAFPAASTIKLPLLVALFEEVD +AGRVKLNETVVMRRDLMTGGSGTMRKRPGTKFSLLETVTKMITISDNTATNMVIDRLGGK +ARLNQRFRNWGLQNTVIRNLLGDFKGT------NTTSPKDLARVGALISNNLLLSNSSRA +KVLDIMHRVEN-KAYLASGFGRNAKFAHKTGTLGI-VLGDAGIVTMPNGKRYLAGIMVNR +PFRD-RRAKSFIKQVSRMVYGH- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus parviboronicapiens TaxID=436516 RepID=UPI0006D109FD +----EQMLRQLLQKSPYKMHMIVKDLSTDEIIiSERYDDVFSSASLIKVPILLAVLHHVQ +TNKVALHQVLTISPKDWVDFSGISEQQLQA-ASIYELLVWMIITSDNTATNVLIDFM-GM +NVLNRYFREIGLTHTILQRKMMDFER-LANGVDNVTTARDMTHIFTHMYHQDLLMPSYSA +LAIDILSRQRV-HESLRRYLIDDVTIAHKTGGLET-VDHDVGIVYSDAK-DYLIGVFITE +VTNN-QDARQLIGRISKVVYEY- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas TaxID=13687 RepID=UPI000EAEACA5 +----VNRLSDLAQNFNGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD +QGRIHLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP +PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ +WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD +TPRPINERQLLMQGVVRAIVA-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. ABOLE TaxID=1985878 RepID=UPI0013E038DC +----VNRLSDIAHDFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD +QGRIRLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP +PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ +WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD +TPRPINERQLLMQGVVRAVVAE- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas TaxID=13687 RepID=UPI0013DEBAC3 +----VNRLSDIAHDFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD +QGRIRLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP +PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ +WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD +TPRPINERQLLMQGVVRAVVAE- +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. SDF0037 TaxID=2133752 RepID=A0A544UTL3_9BACI +----KQTITQILQKAPYKVHMFVKDCKTEHFFiSEKLEDPFSSASLIKVPILLAVLNYIE +SNNLSLEQEIKIAPEEWVDFSVISEQRLEQ-STIYELLVWMIITSDNTATNILIDFL-GM +DTLNQYFRQIGLLQTTIQRKMMDFER-LAKGFDNTTTAKDMALLFSRIYRRDLLSSASSE +VTIGILSRQRV-HESLKRYLVDDVKFAHKTGGLNT-VDHDVGIVYNSSGD-YLIGVFVTE +VTN-NDHARQLIGRISKVVYDY- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas TaxID=13687 RepID=A0A543LTQ3_9SPHN +----VNRLSDLAQNFNGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD +QGRIHLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP +PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ +WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD +TPRPINERQLLMQGVVRAIVA-- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. AG:487_50_53 TaxID=1897014 RepID=A0A1Q6HM45_9BACT +--SLAERIDSILSGRRMTVGVSAEC-GDFSYV--RNARVRFPLMSVFKVHVAMKVLADMS +ASGTSLDTVVHVERAMLREYSPLRDARPSGDITLAGLMRYSVAESDNNACDILIRMAGGI +GQVDRYVRSLGVDGFRLMHNEDAMHRDITRCYDNWSTPEAMTRLMKIVFEGSA---PLYA +PLRSMMAATVTGADKIRAGVPESLPVAHKTGSSDKTGDNDVAVVRMPSGRNCYITVFIKD +SAETDAVNAAVIAAVAREIVE-- +>[subseq from] serine hydrolase n=1 Tax=Microcoleus sp. IPPAS B-353 TaxID=1334624 RepID=UPI001357D54E +--DLTGQLQGLVAEYELTPGLMVVDVTTGDYA-QMGQDRPFAAASTIKIPILVAFLQAVD +AGQVRLDERLRLEESHIAGGAGRLQDEVPGSFSALEVATLMMVQSDNTATNLIIDRLGGL +ATLSSQFREWGMQETVLEDWLPDLQGT------NQTTPRELAGLLAQIERGELLSMASRD +RMLRIMMLTQN-NGLLPQGVGEGGVIAHKTGNLRF-VLADAGLVDVVNGRRYVLVALVER +PEY-EEEAADFIRELSARVYGYf +>[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00073BF40F +------------KASCGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEA--------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Parabacteroides distasonis TaxID=823 RepID=A0A1Y4IR27_9BACT +-kTIEKALLEYVSDKDARIGIAVI-VNGTDTV-SVNGKRDFPMMSVVKFPLALTVVQWID +ANGLSLNDSIAFSEKALKEYSPMLKRYGKKRMTIRELLEWSLVESDNNAADILLNHVGGI +SGATKIMRKIGVDNIEIGASEDDMHRDPYLSYLNRTTPLAMAELFDRFDNEMRNTSLSYS +EIATMLEQCRTGIDRLVAFLSSDATIGHKTGTGFISAINDCGYVNLPNGARYSIAVFVAD +SGYDMAETSAIIAEISRIVW--- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2P1JHI0_ECOLX +-----EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD +AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETXLN----------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=2 Tax=Sphingomonadales TaxID=204457 RepID=A0A2E0Q6F1_9SPHN +---LDDQLFALGTGLDGKVGIAVYDPARGRMV-HFKGTRLYPQQSVSKLWVALTALDMAD +RGQLGLGETGTVRMGDLAVHSPIRQNVIAQGSTYADFIKRALTQSDNTANDTVLRRVGGP +EQVRKTLAKKGFADIRFGPGERPMQSAYVDDPVDGATPVAIAAALAQLKQGELLSPANTA +QFLGWLGEVKSGPNRLKGGLPEGWSIAHKTGTGQQAGYNDVGILTAPDGSIYTVAVMIGR +THVSIPERMEMMHGVVRAIAG-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas pokkalii TaxID=2175090 RepID=A0A2U0SJ89_9SPHN +--ALLNAVQALGAGFQGQVAISVRDIDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID +HQRLSLATPVTVTRADLTVHQPIRPLIGPNGTTVGALLECALTRSDNTCNDVLLWKVGGP +AAIRRMLKEKGIDGVGFGPGERELQARYLAAPYDGATANGVTLGLSLLAQNRLLDRASTD +RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPDGHRYAVAVMIAS +TRQPIPVRMRLMGDVTRAVIR-- +>[subseq from] CblA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SJC4_9BACT +---------------------------------------------------ALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD +FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD +SYETDEDNADIIARISRMVYDA- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=J9V7B1_ECOLX +------------RQSGGRLGGALINTADNSQI-LYRADERFAECSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQ----------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Rhodoferax koreense TaxID=1842727 RepID=UPI0009F841BE +--RMQAEFTRIETQSGAGLGVYVRDLGTGHAA-SHRAEETWYLASTVKVPIAIAVLRGVD +RGDYRLDTRLVLRDTDLVDGAGQTKQHVGAPLSIRYLLNQMIVYSDNTASDMLIGLV-GI +DAVNAVVHELVPQGFQRITTLADVRRAYYATGLNSGRLDAYADLLELLARGKALSAGSTK +YLLGVMERVRTGPNRIKAGLPPRAHFAHKTGTQR-ARTCDSGVVTLPGRDQRVVVVACTS +GELSSTRSDHTLRQVGTALCK-- +>[subseq from] Beta-lactamase n=1 Tax=Koribacter versatilis (strain Ellin345) TaxID=204669 RepID=Q1IIZ9_KORVE +-qKMTADVTAVQQHFDGVMGITIRDLTDNREF-TLNPDDIFPTASSIKLPLLVELWRQSQ +TGTQKLTDLYTFRKEDVVPDSAIMENLTPGVVTNRDLAGMVVAVSDNSATNVLIDRV-GF +DNVNKMLDAQGLHKTRLRRHMMDLAAA-KAGNENVSTPHEMTQLLEAVYRGKILNPQMSE +DFWNLMCTKKE--SPLPRLLPEDLRIANKPGELD-GVRTDSGLVFLKNR-PYVISVMTTY +AA-NEREASAAIAQISLIAYNYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella aquatilis TaxID=34038 RepID=U6A6G8_RAHAQ +-------------------------------------------------MAASAILKESE +VKKDLLTQHVELKKSDLVNYNPITEKHLNDGMTMGELAAAALQYSDNAAMNKLIEHLGGP +QKVTDYARTLGDKTFRLDRTEPTLNTAIPGDDRDTSTPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPVTWVVGD-------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=3 Tax=Calothrix TaxID=1186 RepID=A0A2H2XXG1_9CYAN +--ALETQINTLMNRYKLSPGIFFLDLQTGDYL-NINAEKIFPAASTIKYPVLVALFEEVD +AGRVQLNETMVMQRRHLAGGSGNMRFRSTGTFSLLETATRMMTISDNTATNMVIERLGGI +AKLNQRFRAWGLEQTAMRNMLGDFGGT------NKTSAKDLVRLSALVTNSQLLSDASRT +QVLNIMYRCQN-RRLLPSGLGKGANIAHKTGTLRF-VLGDAGIIQTASGRRYLAGILVRR +PHHS-PQARDFIRQVSQLVYTH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Citrobacter freundii TaxID=546 RepID=A0A1D8MAM1_CITFR +------------------------------------------MMSTFKVLLCGAVLSRID +AGQEQLGRRILYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPYDERDT-MPVAMATTLRKLLTGELLTLASRQ +Q----------------------------------------------------------- +----------------------- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=UPI000D72A331 +------------------------------------------------------------ +----------------MVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Serine hydrolase n=1 Tax=Pigmentiphaga aceris TaxID=1940612 RepID=A0A5C0AUR4_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +ARVQAFTRSAELKAADLQDTMRDAYARYYQRGLNTATMEGYGAMLEKLVQGKLLPDAKRD +MLFEYMKINEPGEYRLAGGLPRKTSFIHKTGTQFE-RACHVGVINPRESAAIVVAACVEG +VDEN-KPAENLLREVGQAVAQ-- +>[subseq from] serine hydrolase n=1 Tax=Alkaliphilus sp. LacV TaxID=1482732 RepID=UPI00125D3641 +------------QGVEANVSIVLNDLTRDKWVlRYKENKKFPSASTIKILIMVEALKQVN +EGKFTLEQKITAKDSDRVEFSIISELNIS-EYTFKDLIILMIIISDNTATNMLIDMV-GY +ESINKMAGVLGLSSTVLKRKMMDFEAA-KAGRQNETSAIDMAKILQKIYNKSILNEEMCE +IMIDILKRQKH-KDSLSRYITDEVTIAHKTGELDR-LNHDIGIFYLEDI-HYILGVFVTD +AQ-DNLEAKRIIGSISKLVYEHf +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter litoralis (strain HTCC2594) TaxID=314225 RepID=Q2N5T1_ERYLH +---FEQRVAQLADGTDGRIGVYALDLSTGREI-GVLADQPFPMASTSKVAIAAVYLAGVD +AGKWSLSSEWRLPR-------------PGGKVPAKTLLDLMVSKSCNDCTDALLSAVGGP +EAVNRWMRQAGISGFQLNRTIRTLINASQIDHRDAATPRAMGQFLAGIHQGRWLSASSRR +VLLDAMLGTTTGDRRMRSALPMSANLAHKTGTLSR-TASDIGLFRTSDGRIIAAAIYVTG +QSSSMSAEN-------------- +>[subseq from] class A beta-lactamase n=1 Tax=Odoribacter sp. Z80 TaxID=2304575 RepID=UPI00137AC775 +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN +TNGMFLNDTVTFSEKAMKEYSPMLKKYGKSRMTIRELLEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS +EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD +SNYDIATTSAIIAEVSKIVLE-- +>[subseq from] Serine hydrolase n=2 Tax=Caloramator sp. E03 TaxID=2576307 RepID=A0A5B7TJW3_9CLOT +--------KSQMNEYDIKYSLSVKRLDTGQEF-NINENEVVPSASTIKVFIMAEAIRQMK +EG-IVKNERIKVSTKDYVPYSIISLLNPENTYTMMDLITLMIIQSDNTATNVLIDIL-GM +DKINAFIKSIECNSTILERKMMDLDVR-KRGLENKTTSKDLTHFMELLYKGRIVDEKSSK +TMIDIMKHQLD-SSMMRYFIPEEIEVANKTGELD-GIDNDTGIVYLNKGD-YIFTMMTRD +AK-SNNEARFAIAQVSKIVYEYf +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter jejuensis TaxID=795812 RepID=UPI0013697D7E +---LDDAVFTTANVFEGYVGIAIRDIERGRVI-HFNGERMFPQQSLSKLWVALAALEKVD +EGELDLAEKVSIRRSDLTVHQPVRKIVLARGTDYGDLLRRAITESDNTANDMLLRRVGGP +PGVRNAIAAGDLGAIKFGPGERAMQSGYVNDPVDGASPNAIAAALARLAQGDLLEPPTTD +LFLRLLDAVKSGPNRLKGGVPEGWSIGHKTGTGQQAGYNDVGILTAPDGHRYAVVVMIGR +TATPVPERMELMHRIVAATVAY- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6DGR6_9BACT +-kKLELRIDEIAMRFDGVMGIAIVDLTDGRPAlLRNAEHVFPAASSIKLPILLELYHQDE +KGKATLDDLYTVDPKDLVEDSRVMGGLSAGVVTNRDLAQFMVAVSDNTAANVLIDRI-GK +DNVNATLRGLGLTKTMLRRKMMDVTAAQ-RGDENVATPHEMVQLLEAIYKGKVLKADSTK +QLIKQLSTLKP--SYIPRDLPDGVQVANKPGELE-GVRTDSGIVFSANR-PFAISVMTAY +AS-DERAAERAISDVAREAYHYf +>[subseq from] Serine hydrolase n=1 Tax=Spirosoma sp. 48-14 TaxID=1895854 RepID=A0A1Q3WY39_9BACT +--ELRQQIEQELARHPGVFAVAFKDLTTGQEL-LIREKELFHAASTMKTPVMIEVYKQQA +QHKLSLSDSILVKNESIVDGSPFSYKQLGTKRTLASLVYDMITVSSNLATNLIIEKI-DA +RKVTQTMRELGANDIQIWRGVEDSKA-FAKGMNNATTAYDLMVIYNKLAQGKVVSPEASK +AMIGVLLEQKF-NESIPAKLPKEVKVAHKTGSIT-GVRHDSGIVYLPDGRKYVLVILSKQ +IKDD-IETQNAMATISEWLYHY- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium sp. oral taxon 203 TaxID=671211 RepID=A0A223AZM1_9FUSO +-tEWKKEIEKIISQVDGKVCINFYDLDKKNSF-SINGNEKVLSASMIKLLILAELMKKVS +ENKFSLSDTITITNFMKTRGDGVLKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLKETFLERRMMDAEA-RKNGYDNYTCADDISSLLKLIYQEKLINKEASQ +FMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGDK-VYILVVLTSG +MS--NLECKQTIGKISKFVYDK- +>[subseq from] Beta-lactamase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E4CVF7_9SPHN +------------------------------------------------------------ +------------------------------GISGREHLDLMITRSCNDCTDALLKAVGGP +RAVNAWMRQAGIYDFELTRDIATLVRASQIAFEDSATPRAMGQLLAGIYQGKWLSAYSRQ +VLMNAMSGTVTGKRRMTSALPDSANLAHKTGTLSR-TASDIGIFFTPDGRPIAAAIYVTG +QSPSMAVE--------------- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=A0A2N6TJD3_FUSNU +-tEWKKEIEKIISRVKGSVCINFYDLAKNNGF-SINGDKKVLSASMIKLLILAELMKKVS +ENKFSLSDAITVTEAMKTGGDGVLKELNSGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINQLGRELDLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQKKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILAVLTNG +MP--NFQCKQTIGKISKFVYDK- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. BK036 TaxID=2512122 RepID=UPI0013EEBEBF +--DLLNAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD +RGQMSLADPVTVTQSDLTVHQPIRALVGKDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP +AAINRMLATKGVAGVTFGPGERHLQARYLAAPIDGASSNGVTLGLSLLAQGKLLSPRSTT +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS +TRQPIPARMRLMGDLTRAVVA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V570_9BACT +------------------------------------------------FMAASAILKESE +VKKNLLTQHVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP +NKVTDYARTLGDNTFRLDRTEPTLSTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWIV---------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Calothrix elsteri CCALA 953 TaxID=987040 RepID=A0A2A2TQL0_9CYAN +---LKTQVQTLMAKNKLAPGMFFLDLESGDYL-DINGDKVFPAASTIKYPVLIALFEQVD +AGKIKLDETLVLRSSQKAAGSGTLQYQASGILSVAETVNKMISISDNTATNMIIDRLGGK +EKLNQRFQNWGLQSTVIRNRLGDFKGT------NTTSAKDLVRLSALIENHKLISDTSHL +QVIEIMRNCHN-AKLLAAGVGKGGKIAHKTGDIGF-VVGDAGIIEMPNGHRYLAGFFVRR +PH-DDERGREFVRRVSRMVYEHf +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium pseudoperiodonticum TaxID=2663009 RepID=A0A2D3NZC0_9FUSO +-tEWKKEIEKIISEVKGQVSVSFYDLDKSTSF-SIDGDKKVLSASMIKLLILAELMRQVS +EAKLSLSQKITLTDSMRVGGDGILKVLDSGHFSLKELAKLMIVVSDNEATNILIDLL-TM +ENINALGRNLALKETFLQRKMMDSNAK-EKGYDNYTSSDDIALLLRLIYEGKLINEEASE +IILDILLQQQQ-SERLQRYLPSDTKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTGA +MP--NLECRETIGKISKYIYN-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Calothrix TaxID=2619626 RepID=A0A2H2Y4T3_9CYAN +--ELQTLIKSLMAKYRLTPGIFFMDLQTGDYI-DINGAKAFSAASTIKYPILIALFQEID +AGRVKLDETLVMRRTVMVGGSGNMQEHAGKKYSLLETATQMMTVSDNTATNMIIDRLGGI +AKLNQKFRSWGLQSTIMRNRLGDFSGT------NKTSAKDLVRLSALMASNQLLSEASQS +QVTQIMYGCHN-RTLLPSGLGSGAKIAHKTGTLRF-VLGDAGIIETLSGKRYLAGIFVHR +PDND-NRARDFIRQVSQVVYGYf +>[subseq from] serine hydrolase n=1 Tax=Hassallia byssoidea TaxID=482630 RepID=UPI000585BD16 +---LNSQIKALMNRYSLNPGMFFLDLQTGNYV-DINGEKIFSAASTIKFPVLVALFEEID +AGRIKLNEKLVMRRGLIAGESGTMQKPVGTKFSVLQTITNMIVISDNTATNMIIDRLGGE +TKLNQRFRNWGLQNTVIRNNLPDVGGT------NTTSPKDLVRLSALLSNNRLLSPQSRN +QVLAIMRGTRN-RSLLPAGIDKKAIISHKTGTLRF-ILGDAGIIQMPNGKSYLAGILVRR +PNYD-DGAVSFIRQVSRAVYNY- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. BK036 TaxID=2512122 RepID=UPI001029D709 +-----NAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD +RGQMSLADPVTVTQSDLTVHQPIRALVGKDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP +AAINRMLATKGVAGVTFGPGERHLQARYLAAPIDGASSNGVTLGLSLLAQGKLLSPRSTT +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS +TRQPIPARMRLMGDLTRAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium TaxID=1978525 RepID=A0A4V1ZXX8_9SPHN +-qELVSSLEALVRNFSGVAGVSVASVDEGWLI-SAGGERKLPQQSVSKLWVTMTVLDQID +QGKLSLDTPLSFTTEDFTVHQPIAALVKPGQTNVAEVIRRAMQMSDNTCNDKLLRLVGGP +DAVRDFIARRSLGPIRFGPGERLLQAAYVLDPPDGAAPLAIAGALARLKRGELLSPSSTE +WLIKTMEAAKTGRSRVRAAVPVGWSYGHKTGTGQTAGFNDVGIMTAPDGRGYAVAVMIGD +TARPVRERQLLMQQVAAAIVA-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. NFR04 TaxID=1566283 RepID=UPI000B824F4B +----VNRLSDIAHNFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD +QGRISLNDPLVITRADFTLHQPVASLVKSDQSTVGEILRRALTMSDNTCNDKLLRLVGGP +PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ +WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRAYALAVMIGD +TPRPINERQLLMQGVVRAVVAE- +>[subseq from] serine hydrolase n=1 Tax=Fusobacterium pseudoperiodonticum TaxID=2663009 RepID=UPI000C1BE80D +-tEWKKEIEKIISEVKGQVSVSFYDLDKNIAF-SIDGNKKVLSASMIKLLILAELMRQVS +EAKLSLSQKITLTDSMRVGGDGILKVLASGHFSLKELAKLMIVVSDNEATNILIDLL-TM +ENINALGRNLALKETFLQRKMMDSNAK-EKGYDNYTSSDDIALLLKLIYEGKLINKETSE +IILDILLQQQQ-SERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTSA +MP--NLECRETIGEISKCIYDK- +>[subseq from] Beta-lactamase n=1 Tax=Tolypothrix campylonemoides VB511288 TaxID=1245935 RepID=A0A0C2QBK0_9CYAN +----NSQLKTLMGRYSLSPGMFFLDLDTGNYL-DFNGEKVFPAASTIKFPILVALFEEVD +AGRIKLNETLVLRRDLKAEGSGILQYPVGTRLSVLDTATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALITNDKLLNNTSRS +KVLGIMRRVQN-RRLLPAGLGKGAVIAHKTGTLGV-LLGDAGIIELPSGKRYLAGILVKR +PFGD-TRARVFISQVSKLVYG-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. NFR04 TaxID=1566283 RepID=A0A1I3UXT6_9SPHN +----VNRLSDIAHNFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD +QGRISLNDPLVITRADFTLHQPVASLVKSDQSTVGEILRRALTMSDNTCNDKLLRLVGGP +PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ +WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRAYALAVMIGD +TPRPINERQLLMQGVVRAVVAE- +>[subseq from] serine hydrolase n=1 Tax=Rufibacter roseus TaxID=1567108 RepID=UPI0013725D12 +--KTEAQLREMIDASPAVTGLVAVDLTSGETF-SFNQDVQFPQASAIKVPILLEVYKQAQ +EGKFALTDVLSIEPATVVGGTGIIKDLVDTSFSIRNLAVLMIALSENTATNALIDLV-GM +QNINKTMQNMGLKQTRVQRKMIQAAAS-GRGEENISTPADAAKMLQMLYKGEFLNKATSQ +EILSILLKTDRQTSRLSAGIPQHVPLAFKPGILN-GVSTEWAIVLLPER-PYAIAIMESY +KQ--SGKAEKIMEEVSEVLYNYf +>[subseq from] Serine hydrolase n=1 Tax=Merismopedia glauca CCAP 1448/3 TaxID=1296344 RepID=A0A2T1BX38_9CYAN +---LKRELLSVVKEYSLSVGMFFLDVDTGEHI-DIGGARVFPAASTIKMPILIALFQDVD +SGRVKLNQTLVMRRKHVTGGSGTLQKRVGAKLSVLDTASRMIIISDNTATNMIIDRMGGI +ARLNSRFRSWGLRDTVMRNWLADLRGT------NKTSSKDLARVLTLVSKRRLISDGSRQ +KVLGILRRTKT-RTLLPSGIGPGARIAHKTGDIGF-LVGDAGLVEMPGGKRYVGVVFVRR +PY-DSPLARKFVKRVSRLVYNY- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. TDK1 TaxID=453247 RepID=UPI000A01C92C +----VNRLSDIAHNFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD +QGRIRLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP +PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ +WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD +TPRPINERQLLMQGVVRAIVA-- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFOXYA2_FULL_39_19 TaxID=1797957 RepID=A0A1F9X1D0_9BACT +-eKLNNEMMENINKFPGEVGIYIKDLKTGVVL-SYNESKPFASASLVKIPIMAATFQAVE +DGNMSLSSKMTMLRKYKAAGSGSMKRNRKGTYTVEQLVYNMITDSDNTATNMLTYEL-GF +GYINWVFQKLGLEVTRFDRGIMDLRLR-NKGIENYTTAKEMGDLLEKMYNKKLVSKESSN +KMLDVLAHQKH-NDRIPRFLPNGLNVAHKTGLLR-GICHDAGIVFTDKGD-FIVCVLTRD +FG-SYKLAKNFIGEVAYITYRCy +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TDK1 TaxID=453247 RepID=A0A196NGH6_9SPHN +----VNRLSDIAHNFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD +QGRIRLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP +PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ +WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD +TPRPINERQLLMQGVVRAIVA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Blastocatellia bacterium TaxID=2052146 RepID=A0A353C7Q8_9BACT +-qTLSKRFGSIAEEAKGKVGVYALVLETGEFA-VLNPTERFAMQSVVKVPISMAVMKMVA +DGKLTLDTRIKIEKEEFVPHSPIRDKIPNGGLTIGELIESAVSVSDGTASDVLQRVAGGA +KGVQAFIDQLGVSGMKIRHTHKEFAADWDLQYENSITAESAVRLLQKLWDEKAASPQKEL +ILLNHMYRTPTGPNRLKGLLPPGTPVAHKTGTGRTSATNDVGIITLPNGDH--------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Bacillus cecembensis TaxID=459347 RepID=UPI00071710CF +----QQQLAQLLDDIPYRVHVIIQDYRTNQLFiEKNKDAVFSSASVIKVPILMAVLHHLE +KTNGQLSQKVPITDTNIVDFSVLTEQQ-QKKATLHELLLWMIITSDNTATNMCIDLI-GF +EALNDYFQHIGLKSTAVQRKMMDFERQ-QQGLDNVTTARDMQHLFQQIYAGTLLAREWNE +VALNILLRQRS-HESLKRYLVDDVKIAHKTGGLDT-VDHDVGIVFTEQVD-YFIGVFLTE +VT-DNDKARQYIGQISKIAYAYf +>[subseq from] Peptidoglycan glycosyltransferase n=3 Tax=Calothrix TaxID=1186 RepID=A0A2H2X753_9CYAN +--SLSSQIKSLMSRYSLDPGMFFVDLETGNYV-DYNGEKAFSAASTIKYPILIALFQEID +AGRIKLNETLTMRRDLMTGGSGTMQYQAAGTFSLLETATKMITISDNTATNMIIDRLGGR +NKLNPRFRSWGLQNTVIRNLLGDFKGT------NITSAKDLVRLSALVANNQLLSNSSRT +RVLDIMRRVKN-TSLLASGLGRGATIAHKTGTLGV-ILGDAGIIQMPNGKRYLAGIFVRR +PFGD-ARGTSFISQVSRTVYG-- +>[subseq from] Beta-lactamase class A n=1 Tax=Thermohydrogenium kirishiense TaxID=937254 RepID=A0A4R4A918_9FIRM +---LYDDIKRFINNTDGNIGVSIKNLKTGERI-DINEEMMFPSASTIKIVIMAQIFKMAK +EGYIRLTDNIILSDFMKTNGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM +KNINKMAEDLGMLHTKIQRKMMDFEAA-KSGKDNYTCPKDMTHLLELIHDGKVVDEEYSI +KMIEILKKQQE-FGRLNLYLPDDVLIAHKPGELKS-LEHDVGIVFLKDCD-YIISVMTNN +MNTN-LDGRMAIGKISKMVYDEy +>[subseq from] class A beta-lactamase n=1 Tax=Prevotella lascolaii TaxID=1776379 RepID=UPI00083AC805 +--SLAERIDSILSGRRMTVGVSAEC-GDFSYV--RNARVRFPLMSVFKVHVAMKVLADMS +ASGTSLDTVVHVERAMLREYSPLRDARPSGDITLAGLMRYSVAESDNNACDILIRMAGGI +GQVDRYVRSLGVDGFRLMHDEDAMHRDITRCYDNWSTPEAMTRLMKIIFEGS---TPLYA +PLRSMMAATVTGADKIRAGVPESLHVAHKTGSSDKTGDNDVAVVRMPSGRNCYITVFIKD +SAETDAVNAAVIAAVAREIVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V597_9BACT +------------------------------------------------FMAASAILKESE +VKKKLLTQHVALKKSDLVNYNPSTEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP +NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWIV---------------------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RBG_16_66_12 TaxID=1797940 RepID=A0A1F9UYB6_9BACT +--KMTSQLDNLSARYPGRVSIFLSDLRSGKTW-MHHPDDLFPAASLIKVPIMIAAFYKMK +DGQLSLDERLAISRRNRVGGSGSLKWRPDGTLAVRDLLMYMINESDNTATKMILERL-GL +GYVQQQFPRIGLLYTGIYEEGMSIKGG-RVAHENYTTAREMTMLLEKIYKGEAVDKASSE +FMMEILKRPKAVPSRLAKGLPVGWEIAHKTGLLRQ-ACHDSAVFLTPNGD-YAMTVLTGQ +NQ-SYSQAKTLITKLAHVTFANy +>[subseq from] serine hydrolase n=1 Tax=Spirosoma aerolatum TaxID=1211326 RepID=UPI0009ACAAE3 +--ELRQQIEQELARHPGVFAVAFKDLTTGQEL-LIREKELFHAASTMKTPVMIEVYKQQA +QHKLSLSDSILVKNESIVDGSPFSYKQLGTKRTLASLVYDMITVSSNLATNLIIEKV-DA +RNVTQTMRELGANDIQIWRGVEDSKA-FAKGMNNATTAYDLMVIYDKLAQGKVVSPEASK +AMIGVLLDQKF-NESIPAKLPKEVKVAHKTGSIT-GVRHDSGIVYLPDGRKYVLVILSKQ +IKD-DIETQNVMATISEWLYRY- +>[subseq from] Serine hydrolase n=1 Tax=Nostocales cyanobacterium HT-58-2 TaxID=1940762 RepID=A0A1Y0RVY5_9CYAN +--QLNSQLKTLVTRYSLSPGMFFLDLDTGNYL-DFNGEKVFPAASTIKFPILVALFQEVD +AGRVKLNETLVLRRDLKAEGSGVLQKPVGTRLSVLDTATKMITISDNTATNMIIDRLGGK +AKLNERFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALITNNKLLTSTSRS +QALAIMRRVEN-KGLLPSGLGKGAVIAHKTGTLGV-LLGDAGIIELPSGKRYLAGILVKR +PFGD-TRAKVFISQVSKLVYG-- +>[subseq from] Beta-lactamase n=2 Tax=Terrabacteria group TaxID=1783272 RepID=R6PMX1_9CLOT +--DLENNLKFLASKYSLKPSVYVWEYESGKHA-DINSTEVYPTASIIKIPVLIQLFRSIE +AGMLKLDDKIAMTQYYKSEGSGSLQFKGNNAYTVDDLARVMITESDNSATNMLMDATGGM +NAMNQSLRKWGMKETRVNDWLPDLQGT------NVTTSKEMATLLYNIDNPNFLSLNSRE +KMVDYMSHVHN-NRLIQAGLPSDAIFIHKTGDIGK-MLGDAGIVYTPNGKKYIVVMLVNR +PYN-SPQGKDFIVAASSLIYNY- +>[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium SW_9_44_58 TaxID=1919144 RepID=A0A2T2RGQ8_9CYAN +--SLKQTFQTLASQQQLNPAAFVVDLDSGKYV-NFQGESRLSAASMIKIPILIAFFQAWE +EGKLQLDESLTITEAVKAGGSGKMQNQPGTEYLALEAAAKMIIDSDNTAANMIIKRLGGK +EALNRLFVQWGLEHTRLRNPLPDFERT------NTTSPKELVTLLAQLSQGELVSARSRD +RIFQILGKTQN-NSLLVQGLDQRASIAHKTGSIAS-LVGDVGIIDSHTGKRYLVAVMVER +PPND-NQAKELIRRYSQETYQYf +>[subseq from] serine hydrolase n=1 Tax=Vibrio breoganii TaxID=553239 RepID=UPI00068081E5 +-----KQVEAITAPLVGRVGFAAQLIGSDKII-AYNGDMTFPMASTYKVPAAVTLLKRVE +AGEVKLDDMVELHLDDMVADNVIAENFVHPGLSVANLIEPMITMSDNTAADFVISLAGGP +KAITDAMRKLGIKDMRIDRNIKDLFRKYEADPRDQSTPFAMLDLLMKIDSATAISEDSRD +FLIASMSRTRTGAGRIKGLLPRGTPVAHKTGTAT-GVAN--------------------- +----------------------- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X665_9BACT +------LLKNVINGKQATVGVAIKNFQSGEEH-YILPDERFALMSVAKFPQVLLLLHLAD +EGKYDPKAPVSFDAEDLKQASSLRKDHPQSALPLTEALRYCIGQSDNITSNKIFELEGGP +RAVEDYVHSLGIADIGVTTDYAHMRPDSPR--QNWGTPRAMLALLEKFHNGKLLSDSSKA +MLWKAMVEATSGHNRIRGGVPAGTLVADKTGTSGTAAFNDVGIVQLPDGGYYGLVVFVGD +SKEPDSVNAAIIAGVSKTVWEHf +>[subseq from] serine hydrolase n=1 Tax=Anaeromusa acidaminophila TaxID=81464 RepID=UPI000368BF63 +-kHLHTKLEQLAASCPCRWSVVVTDGDGRNVY-SLRPDLIYPSASMIKVPILFEILRQAA +AGTLCLQDPLAPSASCRVGGAGILKELNPSLLNIRDLCVLMISLSDNTATNTLIERV-GM +AAVNQTMSDLGLSHTRLQRRMMDFAAA-EAGLQNETTAADVAKLYQLLLNAQGLPPAYAA +LALNILKTQQV-RDKIPFYLPESVSLAHKTGTLD-GVEHDGGVLYLPAG-PYIVCIFADG +LQ-SNAHGLQLIAQMGRAIYDA- +>[subseq from] serine hydrolase n=1 Tax=Fusobacterium pseudoperiodonticum TaxID=2663009 RepID=UPI000C1BE47C +-tEWKKEIEKIISEVKGQVSVSFYDLDKNIAF-SIDGNKKVLSASMIKLLILAELMRQVS +EAKLSLSQKITLTDSMRVGGDGILKVLASGHFSLKELAKLMIVVSDNEATNILIDLL-TM +ENINALGRNLALKETFLQRKMMDSNAK-EKGYDNYTSSDDIALLLKLIYEGKLINKEASE +IILDILLQQQQ-SERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTSA +MP--NLECRETIGKISKCIYDK- +>[subseq from] serine hydrolase n=1 Tax=Mastigocladopsis repens TaxID=221287 RepID=UPI0002EE6327 +--QLNSQLKTLMARYSLSPGMFFLDLDTGNYL-DFNGEKVFSAASTIKFPILVALFQEVD +AGRVKLNETLVLRRDLKAEGSGVLQYPVGTRLSVLATATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALITNNKLLNDTSRS +QVLGIMRRVEN-KRLLPAGLGKGAVISHKTGTLGV-LLGDAGIIELPSGKRYLAGILVKR +PFGD-TRARDFISQVSKLVYG-- +>[subseq from] Beta-lactamase n=1 Tax=cyanobacterium endosymbiont of Epithemia turgida isolate EtSB Lake Yunoko TaxID=1228987 RepID=A0A077JJM7_9CYAN +-----EKIASQEKYAKVKSHGWFIDLDNGNYV-NFNGDTSLSAASTIKIPVLVAFFEELD +AGRIYLDEMLTMDEKIITGGSGSMQQKPGTQFSALEAATKMIVISDNTATDMLVRRLGGK +EVLNKRFKEWGLTKTEINNHLPDLEGT------NTTSPKDLVELLALIERGDLLTVRSRD +RLLGIMQKTRT-QTLLPQGLEQGAMIFHKTGDIGT-ILGDAGIIDIPTGKRYIGAVFAER +SYND-VMGRMIIQDFSRIVYQHf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroidales bacterium TaxID=2030927 RepID=A0A4S1ZGM0_9BACT +--ALTDTLSKITSDYPGKIGVAVI-INNTDTV-AVNNKSIYAMMSVFKVHQALALCNDFD +RKGLSLDSLIAMQRDKLDPWSPMLKEHQEAELPVRELLRYTLIQSDNNASNLMFNRLVDV +ARTDSFIATIPRQSFQIAYTEEEMSADHGKAYSNYTSPLGAATLMNRLFTDSLISKDKQS +FIMETLEQCSTGKDRIVAPLKEGVVVAHKTGSGYTNAHNDVAFIRLPNGKHYTLAVFVKD +FKGNEEEAAKAIARISATVYS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A159YKG6_ECOLX +------------------------------------------------------------ +-------------------------------MSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVI---------------- +----------------------- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7VKI7_9BACT +-qSLSDRIEPLIAKHQGTVCVAIKHLATGETF-FHRPQDVVPTASLIKFPVMIEYYRQVD +EGKLSGDRMVTLTQEDKVPGSGVLTDHFANSLPLETINHLMITFSDNTATNLLLDQI-GI +ANVAKTMQHLGLPETQIHSKVFRRDTSIAQDRSGSTTAADMLSLLEQLHARKLVSSEASE +RMLSHLLSCDD-KTKLLRFLPKEIKGYHKTGAVNE-SRTDAGLFDTPSGW-IAMVCLTSE +NQGDSNAAEILCGRIAQETYEHf +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=filamentous cyanobacterium Phorm 46 TaxID=2107705 RepID=A0A2T1D8A8_9CYAN +----KTQVQILATENTLTAGIFLVDLDTGSYL-NFNGDTPFASASTIKLPILVAFFQAVD +EGKVQLDQMLTLKAEHIVGGSGEMQDAPGKKYSALEVARKMIVVSDNTATNMMIELLGGA +EVLNQHFANWGLRATVLRNNLPDLEGT------NTSSPKDLINIIAQVDRGNLVSVKSRD +RILQIMRQTQN-DSLLPRGLGEGAVIAHKTGNINT-MLADAGMVDLPNGKRYLVAVMV-- +----------------------- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A3D1DR50_9PLAN +--RLAARIKPLVSRHKGQVSVLVKHLGSGRSF-AWKPDRPMPTASLIKLAVMVEVYRQVD +RDRVDLDDRLKLDEDDKVPGSGLLRKYFTTGLTLRDAVRLMIAVSDNTATNLVLDHI-GL +KSTNRTMSRLGHLNTRIHAKVFRRETSIDPDRSGSTTASETVALLEAIHQGKLVSESASQ +QMLEHLQACES-TERIPRFLPPGTVVAHKTGSVSQ-VRTDAGIIGSPAGA-IVICVLTSE +N---------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. 43_108 TaxID=1896974 RepID=A0A1Q6HCJ8_9BACE +-dSLENRLNEAIAGKNAEIGIAVIA--GKDTV-TVNNDAEYPMMSVFKFHQALATSDYLR +THGLELNDTIHISKKELKEYSPLRDKYPNGNITYAELMEYTLQQSDNNACDILFQRTADL +CRTDSFIRTLGIDKFAISVNENDMHVDPKLCYSNWTTPLEAAKLIDAAFTREIVPDPYLS +FIRNTMSNCTTGKDRLPFPLEKDASIAHKTGTSDRDAINDVGYISLSDGRHYSIAVFVKN +SKESDSETAGIIAEISEVVYDY- +>[subseq from] FRAMP1.1 beta-lactamase (Fragment) n=1 Tax=uncultured organism TaxID=155900 RepID=I0AXW7_9ZZZZ +-qDAERRISEMTAGKPAEVGVAWIA--DGKAH-AVNNADGYPMMSVFKLHGAVAELRQME +RRGTPADTLITVRAAEMEKYSPMLKRYGGRDIRLDSLLRYSVAESDNNACDIIMRLAGGT +DGVNAEMRAIGLTGYAITETEASMHADPTRSYNNRSTPLAVAELFRKLYEGGILGEPYAT +LLKDILLSTSTGPNKIKAALPPGATLAHKTGTGFITADNDAGAITLADGRRIYIAVLVKD +SKLGADGNARLIKEIAEAVI--- +>[subseq from] Beta-lactamase class A n=1 Tax=Psychrobacillus sp. OK032 TaxID=1884358 RepID=A0A1H9RFP2_9BACI +--TLQQRIESYIHDIDATFGIYIKHLGTQEEV-NIQGNQLFQMASVFKVPILATLYEKVN +NGEINLHERIRLNEEDYVPGSGVFQEMQYGIPTIKDLATMMIIVSDNLATDKVLSIVGGA +DHVQERMHQMGLNDIYIKHTCWELLSFQNSTGNNVSSAKDMSLLLEKIALDEFISPDCSR +EIREILFKQHF-QQRIGGLLPRNKKVANKTGSLGT-MYNDAGIVYLPDNGEFVITVYSTG +SSLE-YKGDEPIARIAEIAYQYf +>[subseq from] Beta-lactamase TEM n=1 Tax=Solibacillus isronensis B3W22 TaxID=1224748 RepID=K1KHN5_9BACL +----HKQLDRIIAQCPYKVHVIVEDYKTDEIVwKIRAEEIFSSASIIKVPILIAILAHLQ +KTNGSLNQVFKISPENMVDFSVITEQK-QIRATLHELLLWMTITSDNTATNVCIDLL-GM +DAFNDYFNEIGLHNTRVQRKMMDFERQ-KLGFDNVTTAQDMQQLFRKIYRGTLLTSEWNA +VALDILSRQRS-HESLKRYIADDVKMAHKTGGLDT-VDHDTGIVFLEVRD-YFIGVFTTE +VT-DNDKARQTIGAISKIVYEHf +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7JKB7_9BACT +--------TRIAQDSGAYAGVAYIDLGSSDTL-FVNPDSSFHAASTMKVPVMIELFRRAN +TGSFRMDQGLMMVNQSLADGSPYSYHRIGERVRVDSLLRLMITRSSNFATNTLITLV-GA +DAVTKTMRVLGARRIQVRRGVEDGK-AFQAGLNNTTTARDLAIIMRAIEDGKAAPPDATQ +QMLAIMLAQEF-NEKIPAGLPPGIRVAHKTGDIT-AVSHDAAIVYPPGRQPYVLVVLTRG +IT-DGAKSAKLIADISSMVFSH- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7RG39_9BACT +-qSLSDRIEPLIAKHQGTVCVAIKHLATGETF-FHRPQDVVPTASLIKFPVMIEYYRQVD +EGKLSGDRMVTLTQEDKVPGSGVLTDHFANSLPLETINHLMITFSDNTATNLLLDQI-GI +ANVAKTMQHLGLPETQVHSKVFRRDTSIAQDRSGSTTAADMLSLLEQLHARKLVSSEASE +RMLSHLLSCDD-KTKLLRFLPKEIKGYHKTGAVNE-SRTDAGLFDTPSGW-IAMVCLTSE +NQGDSNAAEILCGRIAQETYEHf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas azotifigens TaxID=330920 RepID=UPI000A025FC1 +--ALLNAVQALGAGFQGQVAISVRDVDRGWMV-AWNGDRPNPQQSVSKLWVAIAVFDAID +HTRMSLATPVTVTRSDLTVHQPIRPLVGPSGTTVGALLECALTRSDNTCNDVLLWKVGGP +AAIRRMLKEKGIDGVGFGPGERELQARYLAAPYDGATANGVTLGLSLLAQGKLIGHASTD +RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS +TRQSIPVRMRLMGDVTRAVIR-- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium pseudoperiodonticum TaxID=2663009 RepID=A0A2D3NW79_9FUSO +--EWKKEIKKIISEVKGQVSVSFYDLDKNMAF-SIDGNKKVLSASMIKLLILAELMRQVS +EAKLSLSQKITLTDSMRVGGDGILKVLASGHFSLKELAKLMIVVSDNEATNILMDLL-TM +ENINALGRNLALKETFLQRKMMDSNAK-EKGYDNYTSSDDIALLLKLIYEGKLINKETSE +IILDILLQQQQ-SERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTSA +MP--NLECRETIGKISKCIYDK- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=bacterium TaxID=1869227 RepID=A0A522QFQ7_9BACT +--QLQMRLDTLARHAPGDVAVAVRDLRTGEVV-GYNAHASLPAASTIKVPVMVEVFRQME +AGAFALDRDVSLTSADRDGWGDLADAPANSHYTVRRLLWLMITQSDNTAANMLIRLV-GR +AHVNETMHALGLGNTSLSDYIRSYGDI----RSIRTTASDMVRLMAMIAHGQLVDEWSCG +EMLQIMAGQHI-NTLLPEPLPADVLVAHKTGSLHD-TLNDVGVVYLA-GAPYAIAVMTTH +LA-SLDSGRAFIHAVSSLTFK-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=D1LFI2_9BACT +------------------------------------------------------------ +-----LNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRRLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWT----------------------------------- +----------------------- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A3N5ZUU7_9BACT +--QFAVRLEDIARRVDGVVGYCVVDLTSGTRF-TRLETEVFPTASTIKLAILYELFAQAQ +EGRLALDKPLTLDRAAAVGGSGILFEMGTPTLSLRDYAVLMVVLSDNTATNVLIDAV-GM +ANVNRRMQGLGLTETRLRRKMIDLAAARRG-DENVSTPGEIARLLEAYHKGTGLEPPTVA +AALAILKKGKD--SWLVRAVPSSVPVASKPGDLE-GVRVDAGIVYVPKR-PFIITVMTSW +LQRD-EDGERAIEDLSRAAYQYf +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium canifelinum TaxID=285729 RepID=A0A3P1UYS9_9FUSO +-tEWKKEIEKIISQVEGKVSVNFYDLNKTDGF-SINGNEKVLSASIIKLLILAELLKKAS +ENKFSLSDTITITNFMKTEGDGVLKELNTGHFSLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLKETILERRMMDTEA-RKNGYDNYTSADDISLLLKRIYQEKLINKEASQ +VMLDILLRQQQ-GERLQRYLPTDIKIAHKCGDLDN-LENDGGIIWFGDKA-YILVVLTSG +MS--NLQCKRTIGKISKFVYDK- +>[subseq from] Serine hydrolase n=1 Tax=Sporomusaceae bacterium TaxID=1917525 RepID=A0A402BNM3_9FIRM +-eELRQKIWGILETYTGHFGLVLMNPTTGARL-ELNPTLPFPAASMIKVPIMYEIMRQAA +ANTLSLEDTLIVTNEVCVGGAGILKELRPNLMTVKELITLMIIVSDNTATNMLIDLV-SM +KSINDTMAALGLTATCLKRRMMDFAAA-QKGHENTISAADLALLYAKLLTGSEIPMSYNH +LMLDILKRQQI-RDKLPFYWPEETVLAHKTGTLA-GVEHDGGILFFPGG-PYIVVVLTGN +LDAN-YRGLQLVAEIGQVLYDHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A140IK99_ECOLX +-------------------------------------------------MAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIR------------------------------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonas sp. SG8_28 TaxID=1703357 RepID=A0A0S8B8R5_9BACT +--SLQTAIEHHAATSGATVGVYFRDLASGDSL-LFDADARMHAASMMKVPVLIQLFRDQD +AGRLSLDDSVVITKTSIVDSSTFDYARIGERASIASLAERMITVSSNLATNMLIELV-GA +ARVQATMRELGADSIAVLRGVEDIK-AYEAGLSNTTTARDLGAIFTAIAAGTAASAESCR +EMIAILERQEF-NEGIPAGVPSEVRVAHKTGWIS-GIRHDGGIVTLPDGRRYVLVVLTRG +IA-DVAVADSLIVDVSRLVYD-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas elodea TaxID=179878 RepID=UPI000A0304A3 +--ALLNAVQALGAGFQGQVAISVRDVDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID +HARLSFATPVTVTRSDLTVHQPIRALIGPNGTTVGALLECALTRSDNTCNDVLLWKVGGP +AAIRRMLKEKGIDGVGFGPGERELQARYLAAPYDGATANGITLGLSLLAQDKLLSHGSTD +RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPDGHRYAVAVMIAS +TRQSIPVRMRLMGDVTRAVIR-- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium pseudoperiodonticum TaxID=2663009 RepID=A0A2D3PY58_9FUSO +-tEWKKEIEKIISEVKGQVSVSFYDLDKNIAF-SIDGNKKVLSASMIKLLILAELMRQVS +EAKLSLSQKITLTDSMRVGGDGILKVLASGHFSLKELAKLMIVVSDNEATNILMDLL-TM +ENINALGRNLALKETFLQRKMMDSNAK-EKGYDNYTSSDDIALLLKLIYEGKLINKEASE +IILDILLQQQQ-SERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTSA +MP--NLECRETIGKISKCIYDK- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium pseudoperiodonticum TaxID=2663009 RepID=A0A2G9EDV6_9FUSO +--EWKKEIKKIISEVKGQVSVSFYDLDKNMAF-SIDGNKKVLSASMIKLLILAELMRQVS +EAKLSLSQKITLTDSMRVGGDGILKVLASGHFSLKELAKLMIVVSDNEATNILIDLL-TM +ENINALGRNLALKETFLQRKMMDSNAK-EKGYDNYTSSDDIALLLKLIYEGKLINEEVSE +IILDILLQQQQ-SERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTSA +MP--NLECRETIGEISKCIYDK- +>[subseq from] Class A beta-lactamase n=1 Tax=Barnesiella sp. WM24 TaxID=2558278 RepID=A0A4Y9J486_9BACT +---MEHRLSEYVSGKDATIGIAVI-INGNDTV-AVNGDKDFPMLSVYKFPQALAVADYCK +RHDIGLGDTVAVKATELKIWSPLRDKYGISDVTINELLEYTLQLSDNNACDILFRLIGGT +QAADSLMKSMGYNDIHIISTEDEMHKDLSLCYLNSSTPIAMARLFDRFYREERNGLNTHR +VIGEIMTSCTTGANRLPAPLKSDAIIGHKTGTGDTNGINDAGVVYLPDGNTYSIAVFIKD +SAYDMAETEKMIAEISELVYK-- +>[subseq from] AMIN domain-containing protein n=1 Tax=Chlorogloeopsis fritschii PCC 6912 TaxID=211165 RepID=A0A3S0Y2Q8_CHLFR +--QLNSQVKALMARHSLQPGMFFLDLETGNYL-DINGEKVFPAASTIKFPILIALFQEID +AGRVKLNDTLVMRRDLMTGGSGTMRKRAGSKFSLLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRTWGLQNTIIRNLLGDFKGT------NTTSAKDLVRLSALITNDQLLSSTSRS +KVLDIMSRVQN-RSLLPKGLGKGAIISHKTGTLGI-ILGDAGIIQMPTGKRYLAGIIVRR +PFGD-ARAKSFISQVSRLVYG-- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Melainabacteria bacterium TaxID=2052166 RepID=A0A3S0EFR0_9BACT +--ELRKKIEVVATMKDLRAGVFAADLKTGKFV-DYNGHDEYAAASMIKVPVYVSLLTALD +RKEVSLDQPVEIRQDLVTGGSGWLQWRPGTKVPLREVAELMIIISDNTATNMVIDLLGGK +EKCNRDYVSWGLQKTRINNMLGDFEGT------NKTSPYDMVYLLSRIDRGEIISPESRK +WMYQTMERTRI-RTLLPPGLAPGSRILHKTGDIGT-MVGDAGIVITPTGQRYIVSMQVER +PHND-RRANLLIRALSKMVYRCf +>[subseq from] Serine hydrolase n=1 Tax=Emticicia sp. C21 TaxID=2302915 RepID=A0A372F5J4_9BACT +-eKFKNEIQAKLSTVEGEFAVAFKDLQTGKTL-FINEKDNFHAASTMKTPVMIEVFKQAR +AGKFKLSDSIVVKNESIVDGSSYSYKKIGRKMTIYDLTYQMIIVSSNLATNILIDLV-DA +KNANATMRTLGANDIQVLRGVED-NKAFKLGMNNTVTAYDLMTIFEKLAQEKVVSPEDSK +GMIKILLDQKF-REKIPAKLPAEVKVAHKTGSIT-GVQNDSGIVYLPDGRKYVLVLLSRK +LK-DEKKGVEALADVSRMIFDNf +>[subseq from] AMIN domain-containing protein n=1 Tax=Anabaena sp. 4-3 TaxID=1811979 RepID=UPI00082A8AAF +--QLESQIKSLMRRYSLTPGMFFLDMETGEYL-DINGEKAFPAASTIKFPVLVALFQEIE +AGRVKTNETLVMRRDLMTGGSGNMQQKPGTKFNLLETATRMMTISDNTATNMIIDRLGGK +NRLNERFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLAALISNDKLINRNSYA +QVMDIMRRCKN-RSLLPVGLGKGAAIAHKTGTLGR-VLGDAGIIQTPSGKRYLAGILVGR +PFRD-ARAKSFINQVSRLVYG-- +>[subseq from] AMIN domain-containing protein n=1 Tax=Anabaena sp. (strain CA / ATCC 33047) TaxID=52271 RepID=UPI00082F20EF +--QLESQIKSLMRRYSLTPGMFFLDMETGEYL-DINGEKAFPAASTIKFPVLVALFQEIE +AGRVKTNETLVMRRDLMTGGSGNMQQKPGTKFNLLETATRMMTISDNTATNMIIDRLGGK +NRLNERFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLAALISNDKLINRNSYA +QVMDIMRRCKN-RSLLPVGLGKGAAIAHKTGTLGR-VLGDAGIIQTPSGKRYLAGILVGR +PFRD-ARAKSFINQVSRLVYG-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas elodea TaxID=179878 RepID=UPI000C1E13D4 +----VNRLSDIAHNFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD +QGRIRLSDPLVITRADFTLHQPVASLVKGDQSTVGEIMRRALTMSDNTCNDKLLRLVGGP +PAVRSFIARNALGSIRFGPGEKLLQLSYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ +WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD +TPRPINERQLLMQGVVRAIVA-- +>[subseq from] Beta-lactamase class A n=2 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=R7ZA24_LYSSH +------LIRQLLQETPYKVHIIVKDLRTDETLiSERSTEVFSSASLMKVPILLAVLHHVE +TNRLTLDEVLMITPKDWVDFSVISEQQLKS-ATIYELLVWMIITSDNTATNILIDYM-GM +DALNCYFRENGLKHTILQRKMMDVVRR-ANGVDNVTTARDMAHIFTHIYRQDLFTPSFSA +LAIDILSRQRV-HEALSRYLVDDVIIAHKTGGLET-VDHDVGIVYSDAK-DYLIGVFVTE +VTN-NQEARQLIGRISKVVYEY- +>[subseq from] Beta-lactamase n=1 Tax=Neosynechococcus sphagnicola sy1 TaxID=1497020 RepID=A0A098THL1_9CYAN +--DLQPQVQAVIQRYSLKAGMYFVDLQTGNYL-DIQGDRVFPAASTIKLPILIAFFQDVD +AGKVSLHETLVMRRDLIASGSGDMQDMPGSKFSALETVNKMITISDNTATNLIIDRLGGI +ERLNQRFRSWGLQDTVMHNWLGDFQGT------NKTSSKDLVRLLALMINGRLVSDSSQE +QVLRILRHTTV-KTLLPSGLGPGAVIADKTGDIGF-LVGDAGVIDMPNGRRYLAGIFVLR +PYND-PIVRRFVREISHLVYAY- +>[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. RSMS TaxID=520734 RepID=UPI0010F9CFAA +--NLLNAVQRLGEAFDGQVGISVRDMDEGWTV-SFNGDRLVPQQSVSKLWVAIAVMDAVD +HGKLSLSDPVTVRRSDLTVHQPIRPLVTKSGTTIGHLLKMALTRSANSCNDVLLWKVGGP +KAIRAMLARKGVDDVSFGPGERKLQARYLAAPYDGASADGITRGLMLLKKGKLLSAGSTR +HLLSLMRASRTGPLRLRSGLRDGWTLAHKTGTGQSTGYNDVGILVSPEGHRYAVAVMIAT +TRVPIPTRMRLMGNVTRAIIR-- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. ATCC 53789 TaxID=76335 RepID=A0A367QQ51_9NOSO +--ELKTPIKALMARYRLTPGIFFMDLKTGDYF-SFNGDKAFSAASTIKYPILIALFQEVD +AGRIKLGETLVMRRKHVTGGSGDLQQRVGTKLSLLQTATKMMTISDNTATNMIIDRLGGV +SKLNQKFRRWGLQSTVIHNMLGDFKGT------NKTSAKDLVRLSALVTNNQLISDRSQS +QVLGIMIRCHN-RALLPSGLGSGANIAHKTGTLRF-VLGDAGIIETPSGKRYLAGIFVRR +PNND-IRARDFIRQVSRVMYGYf +>[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. 5-2 TaxID=1926885 RepID=UPI000CD8979B +--KALDELAHRAEGRGGVLGVVVQS-ANGEYA-SVNADRAFTAASLIKLPVMLALLDGVE +AGRWSLDDRLPVR--DRVGGAGILRDLADVALSVRDLVTLMIVISDNTAANLLIDRI-GA +PAVADWCGRHGLRATVLERRMMDAEAR-ARGAENRTSPADMAKLLDGLVRGTLLGPAMTA +FALDVLARQQV-RDRLPRYLPAGLRIAHKTGELD-GLRHDVGIIFTN--APIIVAALTEN +AD----EADDLIAESARRAVQ-- +>[subseq from] serine hydrolase n=1 Tax=Spirosoma sp. BT328 TaxID=2692134 RepID=UPI00141018D5 +-dQLRQQINQELAKQSGVFAVAFKDLGTGQEL-FIREHDVFHAASTMKTPVMIEVYKQVA +QKRLSLSDSIPIKTESIVDGSPYSYKEVGTKRTLVSLVYDMIILSSNLATNLVIEQA-DA +QKVTQTMRELGAKDIQVRRGVEDSK-AFEQGLNNTTTAYDLMVIFEKIATGQAVNPEASK +AMINILLDQRF-TSKIPAKLPKEVKVAHKTGSIK-GVSHDSGIVFLPDGRQYVLVLLSKD +LKND-QAAEDTLATVSELIYQY- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. NFR04 TaxID=1566283 RepID=UPI000B8501B0 +--ALLNAVQALGTGFQGQVAISVRDVDRGWMV-AWNGERPHPQQSVSKLWVAIAVFDAID +HQRLSLATPVTVTRADLTVHQPIRALVGPTGTTIGALLECALTRSDNTCNDVLLWKVGGP +TAIRRMLKEKGVDGVGFGPGERELQARYLAAPYDGATANGITLGLSLLARDKLLSHGSTD +RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS +TRQPIPVRMRLMGDVTRAVIR-- +>[subseq from] Beta-lactamase class A n=2 Tax=Stigmatella erecta TaxID=83460 RepID=A0A1I0KDR4_9DELT +--------QRIAQVKGASVAVAYLNLGDSRDTvFLGAEASFHAASTMKVPVMIEFFRQVD +AGKLSLDQPVPLANRSIVDGSPYTYERLGQAVPASELLKRMITRSSNLATNTLIARV-DA +KRVTRTLRALGARSMTVLRGVEDAK-AYAKGLNNTATARDLATLLAALEQGKAASPRSTQ +AMREILLAQEL-NTLIPAGLPPGTPVAHKTGQIS-GVLHDAAIVYPPGRAPYVLVVLTRD +IP-EAPVAEALIVDLARQVHA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V596_9BACT +------------------------------------------------FMAASAILKESE +VKKNLLTQHVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP +NKVTDYARTLGDNTFRLDRTEPTLNAAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSICAGLPATWIV---------------------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8U3R1_9BACT +--KLESTLDRLASELRGATGYVIRDLDSGETF-EKSGDAIFPAASTIKLPIFIELYKRAE +EGGIDLERPVPIDPKARVEGGGVLEKWSAPYLSARQLSVLMIDFSDNYAANLLTDLV-GM +ESVGRRLRSWGFEDTLLRRRMMDLGAA-RAGRENVTTPRDMAGLLERLQRGQLLNAENTR +AVIDVMKRNEG--TPIKRGLPPGAEAADKDGELE-GVRCDAGLVFVKGGRPLVIAVMTAY +LE-DDAAGEAFIGEVTRAACQY- +>[subseq from] serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=UPI000BFCB17A +-tEWKKEIEKIISQVEGKVCVNFYDLNKNNGF-SINGNEKVLSASMIKLLILAELLKKAS +ENKFSLSDTITITNFMKTEGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLKETILERRMMDAEA-RKNGYDNYTSADDISLLFKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPTDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFOXYA2_FULL_50_26 TaxID=1797960 RepID=A0A1F9WTY4_9BACT +-----AELQARAEKFPGEAAIVIKDIQTQQEI-GINVARLFPSASLVKVPIMAAVYQAQE +EGKLRLEDHIILKKKHKVRCSRLYNMRPGRKVVIRDIIERMITESDNTATNMLVDAL-GF +GYLNQKFIEFGLKQTDLRRGVMDLKW-RKAGIENYTTAADMALLLEKIYNGELVSHAASA +EMLEVLKRQKV-NDRIPRLLPDGLVIAHKTGLLND-TVSDVGIVFTKEGD-FIICVLTAD +IK-SFLSAKKFIGSVAACAYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Anseongella ginsenosidimutans TaxID=496056 RepID=A0A4R3KNA2_9SPHI +---LRERIISRLEAENGTFAVAFHDMDTGKEL-LFNEREVFHAASTMKTPVLIEIYKQAA +EGKLSLDDSLLIKNKSIVDGSLYRYKRIGEQVPLKKLLYKMIIRSSNLATNIIIELA-GA +ENVTKTMRNLGAADIRVLRGVEDLK-AYEKGLSNTTTAFDLLRIYQKMASGEIVSPEASK +AMISTLLDQEF-DRIIPAGLPEDVKVAHKTGSIS-GVRHDSGIVFLPGGRTYVLVLLSKD +LE-DAEAGIAAMADVSEMIYRY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V5A9_9BACT +------------------------------------------------FMAASAILKESE +VKKNLLTQHVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP +NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERGTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWIV---------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E7UC23_9SPHN +------------------------------------------------------------ +------------------------------GISGREHLDLMISRSCNDCTDALLKAVGGP +RAVNAWMRQAGIHDFELTRDIATLVRASQIAFEDSATPRAMGRLLAGIYQGKWLSSYSRQ +VLMNAMASTVTGKRRMTSALPDSANLAHKTGTLSR-TASDIGIFYTPDGRPVAAAIYVTG +QSVSMASEN-------------- +>[subseq from] Beta-lactamase n=1 Tax=Tolypothrix bouteillei VB521301 TaxID=1479485 RepID=A0A0C1NBP0_9CYAN +---LNSQIQALMARYSFLLGMFFLDLQSGDYL-NINGDKAFPAASTIKFPILIALFQEIE +AGRVRFDESLVMRRDLVAGGSGDMQQSVGSRFSVLQTATKMMTISDNTATNMIIDRLGGK +AVLNQRFQSWGLKNTTIRNLLADVNGT------NTTSAKDLVRLSALVTNDKLINNTSRS +QVLQIMRQCHN-QSMLPSGLGSGAIIAHKTGTLRF-VLGDAGIIQTPNGKIYLAGILVKR +PNHD-SRATEFIRQVSRFLYDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Chrysopegis kryptomonas TaxID=1633643 RepID=A0A0P1MZL5_9BACT +hkKTFEKIKFIADTSNGVIGVAIKNLATGETF-LINENLLFPQGSAIKIPILVEVLKQAN +EGKFKLTDKIKIEKKYQVGGSGVLKEFGDGLLSIYDLAVLMITVSDNTATNILIDLV-GM +ENVNKTLEKLGFKNTKLQRKMIRPDAS-ARGEENLSTPFEAMKFMEMLYKGQIVSKEISE +QAIKILKKEKE--ANLNKYLPQNIEIANKPGGIE-GVTCEWGIVFLPRH-PYVIIIMSNY +NL---TSAGETIAQISKIAYEHf +>[subseq from] Serine hydrolase n=1 Tax=Emticicia sp. 17J42-9 TaxID=2492393 RepID=A0A4Q5LVL9_9BACT +-eKLKDAIQAKLATVEGEFAIAFKDLQTGQTL-FINEKDNFHAASTMKTPVMIEVFKQAR +AGKFKLSDSIVVKNESIVDGSPFGYKKIGKKMTIYDLTYQMIIVSSNLATNILIDLV-EA +KKANATMRTLGANDIQVLRGVEDSKA-FKLGMNNTVTAYDLMTIFEKLAQKTVVSKEDSE +GMIKILLDQKF-REKIPAKLPKEVKVAHKTGSIT-GVQNDSGIVYLPDGRKYVVVLLSRK +LK-DEKKGVEVLAEVSRMLYD-- +>[subseq from] Beta-lactamase n=2 Tax=Sphaerobacter thermophilus (strain DSM 20745 / S 6022) TaxID=479434 RepID=D1C5R0_SPHTD +---------AAAEATGGTVGATIVA-PGGETF-RHNGDRRFRAASTVKIPLMIAVYRAVD +AGERALTDRIVLRAADKAPGSGVLLHHDGLELTLEDLVYLTISISDNTATNLLIDLV-GL +DAVNDVIASLGMRDSNLSRKMKGRP-ALPDEPENWATPDDYALAVQALLEGRAASQESCT +AMLAMLEKQQN-PRRIGRYVPEGIRWGSKTGSLT-GVVNDVGFITTPAGT-LVVAVFTEN +LP-DLHAGEQAIGDITRAALQ-- +>[subseq from] PenP, beta-lactamase class A n=1 Tax=Nostoc sphaeroides CCNUC1 TaxID=2653204 RepID=A0A5P8W169_9NOSO +-----LPIKALMARYRLTPGIFFMDLETGDYF-SFNGDKAFSAASTIKYPILIALFQEVD +AGRIKLGETLVMRRKHVTGGSGDMQQRVGTKLSLLQTATKMMTISDNTATNMIIDRLGGV +SKLNQKFRRWGLQSTVIHNMLGDFKGT------NKTSAKDLVRLSALITNNQLISDTSQS +QVLGIMIRCHN-RALLPSGLGSGANIAHKTGTLRF-VLGDAGIIETPSGKRYLAGIFVRR +PNND-IRARDFIRQVSRVMYGYf +>[subseq from] Uncharacterized protein n=2 Tax=Calothrix desertica TaxID=32056 RepID=A0A3S1AMW2_9CYAN +--QLSSQVRSLMSRYSLDPGLFFIDLETGNYV-DYNGEKAFSAASTIKFPILIALFQEID +AGRVKLNETLTMRRDLVTGGSGTMQYRAPGTFSLLETATKMITISDNTATNMIIDRLGGR +NKLNPRFRTWGLQNTVIRNLLGDFKGT------NITSAKDLVRLSALVANNQLLSNSSRA +RVLDIMRRVEN-TSLLASGLGRGATIAHKTGTLGV-ILGDAGIIQMPNGKRYLAGIFVRR +PFGD-RRGREFISQVSRTVYS-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D6UNZ1_9SPHN +---LERQIAQLADGSNGRIGVYAIDLATGREI-GVLADQRFPMASTSKVAIAATFLAGVD +AGKWSLTSEFRLPR-------------PGGAMPAHRHLSLMISKSCNDCTDALLNAVGGP +RAVNKWMQEAGIEGFQLSRDIATLIRAWSVXTKDXATPRAMGQXLAGIYQGXWLSDYSRR +VLLDAMEXTTTGKRRMRSALPLSANLAHKTGTLAR-TASDIGIFHTPXGRAIAAAIYVTG +QSPSMA----------------- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus parviboronicapiens TaxID=436516 RepID=UPI000D3BF00A +----EQMLPQLLQKSPYKMHMIVKDLSTDEIIiSERYDDVFSSASLIKVPILLAVLHHVQ +TNKVALHQVLTISPKDWVDFSGISEQQLQA-ASIYELLVWMIITSDNTATNVLIDFM-GM +NVLNRYFREIGLTHTILQRKMMDFER-LANGVDNVTTARDMTHIFTHMYHQDLLMPSYSA +LAIDILSRQRV-HESLRRYLIDDVTIAHKTGGLET-VDHDVGIVYSDAK-DYLIGVFITE +VTNN-QDARQLIGRISKVVYEY- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. CAG:714 TaxID=1262749 RepID=R6YU04_9BACE +--SLRQELANRIKNCRAQVGAALV-VDGKDTL-TLFNEVPYPLMSVYKLHQAMAVGKYLH +ERGRTSESRIAIGKEDLKPYSPLRDKYPDGNLSVRELLEYTLQWSDNNACDILFAHTGGT +AETDRYIRSLGLKEFAISSTEDEMHRDLDKCYDNWSSPLEMARLLEILFTTDLEMGEFQP +LIRQILMTCRTGLNRLPKPLENGAQIAHKTGTGDKNGINDAGMVFLPDGRRYTLVVFVKD +SWESMEKTEQLIADVSEIVYRY- +>[subseq from] serine hydrolase n=1 Tax=Varibaculum timonense TaxID=1964383 RepID=UPI0009BB49C7 +---INKKIFSIIRCLEGEIGLYFEDLQTGEKL-TINSDNIFPAASTIKIPLVLFLFQIVE +DGMLDLNDVVSISKDNRVMGTGIIKDLNENYPTILDLATLCITVSDNIAANQIIDLVGGT +SKVNEFCKKIGLSNTRLQRKMLDIE-AIKAGKDNYTTAGDMGSLLRQLGKNKIVSKQVSE +RVIEIMKTQQF-RQKLPALIPAVVVVANKTGDLR-GVQNDVGIFIMPGNNIYILAILICS +LAED-SQGIEAIAKISKVVYEE- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00098F8457 +------------------------------------------------------------ +----------------MVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Serine hydrolase n=1 Tax=Bacillus canaveralius TaxID=1403243 RepID=A0A2N5GGI2_9BACI +--SLQNRLEEVLHDATGNFGVYVKHLESGETA-AINQNRFFQAASVFKVPILATLYRDAE +MNRVDLHQRIRLEEKDLVNGSGIFRELIPVEVTIKNLATMMIIVSDNVGTDKILQII-GK +ETVNQYMKEIGLNNTYIRFSCWELLCFQESIENNVTTAADIAKLLQLIASKQLISQHACD +DMFEILAKQQF-RNRIPNLLPENTIVGHKTGTVAS-VVNDAGIVKLPDKKGTLIITAFSI +GNKTEAEGARKIAELSKAAYDHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. LB126 TaxID=1983755 RepID=A0A2M8QW85_9SPHN +--DLLNAVQGLSASFKGRVGISVRDIDEGWTL-SSNGDAPLPQQSVSKLWVAITVMDAVD +RGKLSLSDPVTVRRSDLTVHQPIRPLVTKAGTTVGKLLEMALTRSANSCNDVLLWKVGGP +QAVRDMLARKDIDDVGFGPGERELQARYLAAPYDGASANGITLGLALLKRGELLSRKSTN +HLLALMRASRTGPLRLRSGLRSGWTLAHKTGTGQSTGYNDVGILVSPDGHRYAVAVMIAS +THEPIPVRMRLMGNVTRAIIR-- +>[subseq from] Uncharacterized protein n=1 Tax=[Clostridium] symbiosum ATCC 14940 TaxID=411472 RepID=U2BDQ5_CLOSY +-eELKNRINEFIESQTGNICVSLFDLKEQDGF-SIDGDRRVPSASMIKLVIMAELMRRVC +AGELSLEEKIKITQEMRTGGDGVLKEEPGHEFSLREILTLMIIVSDNEATNILIQML-GM +DRINGMAAELGLKEAVLGRKMMDSEAK-KQGCDNFICADDIMLILKKIYEGSCVNRKASA +LMLDILKRQQQ-SGRLQLYLPEDVEVAHKCGDLDF-LENDGGIILLPGH-PYILAVLTNG +VK-TNKDGREAIGRISQIIYEE- +>[subseq from] Beta-lactamase class A n=2 Tax=Pedobacter luteus TaxID=572036 RepID=A0A1T5B9D6_9SPHI +-eKLKEQIKAELAKQKGTFGIAFKNIQTGEEI-LINERINFHAASTMKTPVLIEAYKQAE +AGKFNIDQPILVKNESIVDGSLYSYTKVGTKLPIYDLLYLMIIKSSNLATNIIIDLV-GA +QNANKTMRELGAHDIQVLRGVEDSK-AFQKGMNNTTTAYDQMLIFEAMATGKIVNKKSSD +AMIKILLDQAF-NDKIPAQLPKNVKVAHKTGWIK-GINHDAGIVYLPDGRKYVLVLLSKE +MT-DDKAGVAAMANVSKMVYDYf +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Saccharicenans subterraneum TaxID=2508984 RepID=A0A3E2BQV0_9BACT +----SRQILQRISSFRGETGLVVKDLQTGWTF-LHNDEARFPAASLIKIPIMVACFKAVE +DGRLDLGEKYVLRRQDRVGGSGLLRRMRNGRFTYAELIDYMVTHSDNIATNVIIKRL-GF +DYISGVFEALGLQDTVLNRLMMDFRAR-EDGLENYTSAREITGLLEMIYHGRCLNASISE +KCLDVLKRQKI-NDRLPRFLPREALVAHKTGQERE-VCHDAGIVFSPHGD-YIITVLVRT +WSGP-LTTKTFIARLSSYFYQVf +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5XP66_9BACT +----------IATRLDGVMSVAILDLTDGRIL-LRNADRVFPAASSIKIAILLELYRQDQ +KGKGKLDDSYTFDPKDLVEDSQIMAGLTPGVVTNRDLAQFMVAVSDNAATNILIDRV-GR +DNVNATLRGLGLTKTMLRRKMMDIGAARRG-DENVATPQEMVRLLEMIYKGKALNKELTD +ELIKRLKTLKK-DSYLSYELPAGVELADKPGTLD-GVRNDSGIVFAPNR-PFAISVMTAY +DR-DEKAAERAISEVALEAYRYf +>[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium sp. VCM10 TaxID=1381751 RepID=UPI000470BB8B +----------------------------------------------------AELLDRTT +--PKELEKNVSWTQADVDEWTPVTEKHVDEGLPLEDVAESALRVSDNLAMNIVLDELGGP +EALDDALEKNGDMTTEVTDEEPELNDVEDGSTDNTTTPAAITADLQSLLDPQRFSDDDRR +VLFDWMSANETGDPLIRAGAPEGWVVRDKSGHSD-AIQNDIAVVTPPDRQPIVVSVMTEA +DDPESEDGPALVAAVAEAV---- +>[subseq from] serine hydrolase n=1 Tax=Dyadobacter sp. 32 TaxID=538966 RepID=UPI0011EBC46E +--TLTQKISAELTKHKGYYAVAFSESSSGKTV-FINEREFFHAASTMKTPVMIEVFKQAN +AGKFSLTDSVTLKNESIVDGSLFRYKRIGKKMVIRDLVYEMITVSSNFATNMLIDLV-GA +GNVTQSMRELGAKDMKVLRGVEDTK-AFEKGLNNTTTAYDLMLIFAKMAQGEIVNQKASK +AMIEILLDQKF-GTVIPAKLPADVKVAHKTGAFGK-VRHDSGIVYLPNGRHYSIVILSRD +WE-DEKETLELLSDVSKMIYD-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Calothrix TaxID=2619626 RepID=A0A2H2XYN0_9CYAN +--TLNSQIKALMSRYNLSPGMFFVDLQTGDYI-DINGNKAFPAASTIKLPILITLFQEIE +AGRVRPDETLVMRRDLVAGGSGDMQNRVGSKFSVLQTATKMMTISDNTATNMIIDRLGGF +YRLNERFRTLGLQNTALRHLLADEYG------TNTTSAKDLVLLSNLIANNQILSDASRN +QILDIMRRCHN-QSMLPSGLGAGAVIAHKTGTLRF-VLGDAGIIQTASGKRYLAGILVRR +PNHD-ARATTFIRQVSHIVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A4P5WCD4_9BACT +--QMEDSVRLIAKGTDAVVGVAILDLTDRRAF-YLNADAVYPTASTIKLAVLAELYRQHA +RAGAKLGDLYTIDSKDVVGGSDIMGGLTAGVVTNRDLATMMMAVSDNAATNVLINRV-GM +DNVNSWLAGLGLKNTRLRRQMMDVQAA-QAGRENTATPRELVLMLETLHKGDALGKTGTE +DFFKMLGTGKM--SYLPRLLPDGVRTANKPGDLD-AVRNDAGIVFAPNR-PFAIAVMTTF +GR-DHREQEMAIARISRTAWSYf +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. NFR04 TaxID=1566283 RepID=A0A1I3MT09_9SPHN +--ALLNAVQALGTGFQGQVAISVRDVDRGWMV-AWNGERPHPQQSVSKLWVAIAVFDAID +HQRLSLATPVTVTRADLTVHQPIRALVGPTGTTIGALLECALTRSDNTCNDVLLWKVGGP +TAIRRMLKEKGVDGVGFGPGERELQARYLAAPYDGATANGITLGLSLLARDKLLSHGSTD +RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS +TRQPIPVRMRLMGDVTRAVIR-- +>[subseq from] serine hydrolase n=1 Tax=unicellular cyanobacterium SU2 TaxID=1981054 RepID=UPI000A19BF15 +-----EKVAAQEKYANVKPTAWFIDLDNGNYV-SLNGDAPLSAASTIKLPVLVAFFEALD +ARKIHLDEMLIMDKEIITGEAGTMQYQPPGTFSALETATKMIVISDNTATDMLIRRLGGK +DVLNQRFKEWGLTNTVINNRLPDLEGT------NTTSPQDLAKLLARVERGDLLTLRSRD +RLLGIMQKTRT-RTLLPQGLEQDAIISHKTGDIGT-ILGDAGIIDIPTGKRYVGAVFAER +PYND-VKGRMVVQDFSRTVYQHf +>[subseq from] Serine hydrolase n=1 Tax=Bacteroides caecimuris TaxID=1796613 RepID=A0A3A9BIT8_9BACE +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPIMSVVKFPLALTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSLMTVRELLEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS +EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD +SNYDIATTSAIIAEVSKIVLE-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf17 TaxID=1735683 RepID=UPI0009EB30B8 +--ALLNAVQALGSSFQGQVGIAVRDVTDGWVV-GYNADAAMPQQSVSKLWVAIAVMDAVD +RGALSLSDAVTVRQSDLTVHQPIRARVGADGTTVSALLDCAMTRSDNTCNDVLLWKVGGP +TAIRRMLTAKRIAGVSFGPGERVLQARYLAAPYDGASANGITLGLALLQRGELLSNASTV +HLLTVMGASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLRSPDGHTYAIAVLIGS +TRRPIPARMQFMGNVTRAVIQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium nucleatum subsp. vincentii 3_1_36A2 TaxID=469604 RepID=C7XRW9_FUSNV +-tEWKKEIEKIISQVEGSVCINFYDLNKNNVF-SINGDKKVLSASTIKLLILAELMKKIS +ENKFSLSDTIMIADSMKTGGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINQLGKELDLKETFLGRKMMDAEA-RKKGYDNYTCADDISLLLKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGDRA-YILVVLTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas pituitosa TaxID=99597 RepID=UPI0009FD978F +----VNRLSDIAQNFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD +QGRIRLSDPLVITRADFTLHQPVASLVKGDQSTVGEIMRRALTMSDNTCNDKLLRLVGGP +PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGAIARLKRGELLSPVSTQ +WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD +TPRPINERQLLMQGVVRAIVA-- +>[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc sp. NIES-3756 TaxID=1751286 RepID=UPI00071EF13D +--QLDAQIKQLMNRYSLSPGMFFLDMETGEYL-DINGEKTFAAASTIKFPILIALFQEID +AGRVRPNETLVMRRDLMTGGSGNMQYRKAGTFSLMETASKMMIISDNTATNMIIDRLGGK +NRLNQKFRSWGLQNTIIRNLLGDFKGT------NKTSPKDLVRLAAMISNNKLLSLNSNA +QVMDIMSRCKN-RSLLPVGLGKGAVIAHKTGTLGR-VLGDAGIIQTASGKRYLAGIMVAR +PFGD-ARAKAFINQVSRLVYG-- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A377UTU8_KLEPN +------------------------------------------------------------ +---------------------------------------------------------AGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Uncharacterized protein n=1 Tax=Lucifera butyrica TaxID=1351585 RepID=A0A498RDJ3_9FIRM +-kELRHKVQSVLSGAGGRWSIVIINQATRERL-EINPAMVFPAASMIKVPILYELMRQVA +AGQLSLDESLIVAGASRVGGAGILQELRPDIMTLRELAILMIVLSDNSATNLLIERV-GM +NAVNQTMTALGLTSTVLRRRMMDFEAA-RTGRENETCATDLALLFELIYTSHGLPDQYGA +LMVDILKRQQI-RDKLPFYLPEETILANKTGTLP-GVEHDGGILFLPGG-PYIICVLSGD +LTFN-YQGIQLIARIGKIVYEH- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5N3F0_9BACT +-kKLETRVDEIANRLDGVMGVAILDLTDGRVL-LRNADRVFPAASSIKIAILLELYRQDQ +KGKARLDDIYTFDPKDLVEDSRIMAGLTAGVVTNRDLAQFMVTVSDNAAANVLIDRV-GK +DNVNAMLHSLGLSKTMLRRKMMDVAAA-RRGEENVATPQEMVRLLEAIYKEKVLDKQATA +EFIKQLSTSKQ--SYIPRYLPENVQVANKPGELE-AVRTDSGIVYAQNR-PFAISVMTAY +DR-DEKAAGRAISDVALEAYHYf +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6LQ49_9BACT +-kKLETRVDEIANRLDGVMGVAILDLTDGRVL-LRNADRVFPAASSIKIAILLELYRQDQ +KGKARLDDIYTFDPKDLVEDSRIMAGLTAGVVTNRDLAQFMVTVSDNAAANVLIDRV-GK +DNVNAMLHSLGLSKTMLRRKMMDVAAA-RRGEENVATPQEMVRLLEAIYKEKVLDKQATA +EFIKQLSTSKQ--SYIPRYLPENVQVANKPGELE-AVRTDSGIVYAQNR-PFAISVMTAY +DR-DEKAAGRAISDVALEAYHYf +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=A0A380FCU8_STAGA +------------------------------------------------------------ +--PQDLNQKVTINKSDIVTYSPVTEKYIGKTMTLRQLIEASMLKSDNTANNKVIQAIGGV +NAFKSELRQLGDCVSEPQRLEPDLNNYDPKKIADTTTPRAAATTLNYILTHSNMHKGNLQ +FLKELMIKNETGDSLIKAGAAKDDIVGDKSGQGTYATRNDLAFIYPKGQKPIILAIYTKQ +SDKNAKPNDEVIAKTAEIAIKY- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. V33-4 TaxID=2054169 RepID=UPI000C78E850 +--SLQNRLEEVLHDATGNFGVYVKHLESGETA-AINQNRFFQAASVFKVPILATLYRDVE +MNRVDLHQRIRLEEKDLVNGSGIFRELIPVEVTIKNLATMMIIVSDNVGTDKILQII-GK +ETVNQYMKEIGLNNTYIRFSCWELLCFQESIENNVTTAADIAKLLQLIASKQLISQHACD +DMFEILAKQQF-RNRIPNLLPENTIVGHKTGTVAS-VVNDAGIVKLPGDGTLIISAFSIG +NK-TEAEGARKIAELSKAAYDHf +>[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter holothuriorum TaxID=241145 RepID=A0A1T5A680_9FLAO +-qQLQKKIAAIFEENQGDFAIAFKNISAEKYNiLINQNENFHAASTMKTPVMIEVFKQAS +EGKFSLKDSLIIRNESIVDGSPFAYEQLGQKRSIKDLVTDMIIYSSNLATNIVIELV-GA +KNVNKTMREIGAMDINVLRGVEDMK-AYEAGLSNSTTAYDLMLIFEALAKGKAVNPEADK +QMLQILRQQKH-TDLIPALLPKNLKIANKTGWIT-GVHHDSALIELPDGKRYVLVLLSKN +MK-DMEAGTRMLAEVSKMVYDH- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6ADW7_9BACT +-kKLETRVDEIANRLDGVMGVAILDLTDGRVL-LRNADRVFPAASSIKIAILLELYRQDQ +KGKARLDDIYTFDPKDLVEDSRIMAGLTAGVVTNRDLAQFMVTVSDNAATNVLIDRV-GK +DNVNAMLHSLGLSKTMLRRKMMDVAAARRG-DENVATPQEMVRLLEAIYKEKVLDKQATA +EFIKQLSTSKQ--SYIPRYLPENVQVANKPGELE-AVRTDSGIVYAQNR-PFAISVMTAY +DR-DEKAAGRAISDVALEAYHYf +>[subseq from] Extended spectrum beta-lactamase VEB (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2S1Q3T5_KLEPN +-----------------------------------------PMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +S---------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium periodonticum D10 TaxID=620833 RepID=K1GKV3_9FUSO +--DWKKEIEKIISEVKGQVSVSFYDLGKNIAF-SIDGNKKVLSASMIKLLILAELMRQVS +EAELSLSQKITLTDSMRVGGDGILKVLASGHFSLKELAKLMIVVSDNEATNILIDLL-TM +ENINALGRNLALKETFLQRKMMDSKAK-EKGYDNYTSSDDIALLLRLIYEGKLINEEASE +IILDILLQQQQ-SERLQRYLPSDTKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTSA +MS--NLECRETIGKISKYIYDK- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI0007E365D1 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNK-------------------------------------------------- +----------------------- +>[subseq from] Imipenem-hydrolyzing beta-lactamase n=1 Tax=bacterium HR10 TaxID=2035405 RepID=A0A2H5VXC0_9BACT +-eKTEARLREIVASARGVMGIVVVDLVSGERF-AINEDLVFPQGSAIKIPILMEVYKQAH +EGRFRLTDRRRLEKAHVVGGSGILKEFGEGLLSIYDLCVLMIVLSDNTATNMLIEMV-GM +ENVNRTMAALGLTRTRLQRKMIDPAAS-ARGEENLSTPAEAARLMEILYRGEFINREVCD +QILAILKKPKR--TAVSAGVPSDVPIASKPGSIP-GVSTEWAIVELRER-PYVIVVMENY +GM--GEEAPAAFREISRTVYDYf +>[subseq from] Beta-lactamase (Fragment) n=3 Tax=Enterobacteriaceae TaxID=543 RepID=A0A140DR55_ECOLX +------------------------------------------------------------ +---------------------------------VGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLR- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Spirosoma sp. BT328 TaxID=2692134 RepID=UPI0014100FC6 +--------TAYIHRLNARISIATKSLADSSLSfYERADERVPSASVIKLPIMIEAMERVK +AGTLDLDEIHILTDSEKTGGDGVLKTYSHRSVSYRDMLRLMMVFSDNTATNIFINEL-GR +DAINQRIRQLGLTKSQLNRVMMDTLAA-RQGRDNYVTAREMGQLLEKIYRKQVATPELCD +QMIDILKQNED-TKTIPSLLPKGTVVAHKTGTLTN-VRGDVGVVYAKSGKPFLLSIFVEG +IA--QPEAERIIGEVAFICYSYy +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Tolypothrix sp. NIES-4075 TaxID=2005459 RepID=A0A218QND1_9CYAN +---LNSQIKALMNRYTLSPGMFFLDLQTGNYV-DINGEKIFSAASTIKFPVLVALFQEID +AGRIKLDEKLVMRRGLIAGESGTMQKPVNTKFSVLQTLTNMIVISDNTATNMIIDRLGGE +TKLNQRFRNWGLQNTVIRNNLPDVGGT------NTTSPKDLVRLSALLSNNRLLSPQSHN +QVLAIMRQTHN-RSLLPAGIDKKAIISHKTGTLRF-VLGDAGIIQMPNGKSYLAGILVHR +PNYD-DGAVSFIRQVSRAVYNY- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5US37_9BACT +-kKLETRVEEIAARLDGVMGVAILDLTDGRIL-LRNADRFFPTASSIKIAILLELYRQDQ +KGKAKLDDIYIFDPKDLFEDSQIMAGLTPGVVTNRDLAQFMVAVSDNAATNVLIDRV-GM +QNVNATMRSLGLTKTMLRRKMIDVAAARRG-DENVSTPQEMVRLFEMIYKGKALNKELTD +ELIKQLKTLKK-DSYLSYELPADVELADKPGSLD-GVRNDTGIVFAHNR-PFAISVMTAY +DR-DEKAAERAISGVALEAYHYf +>[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma endophyticum TaxID=662367 RepID=A0A1I1X695_9BACT +-dQLTQKINAELAKQPGTFAVAFRDLTTGKEL-LIRERETFHAASTMKTPVMIEVYKQVA +QHKMALADSITITTESIVDGSPYSYKAVGTKRTLAALVYDMIIVSSNLATNLVIERV-GA +QNVTKTMRDLGTKDIQVRRGVED-NKAFAQGLNNTTTAYDLMVIFDRIATGKAVSPEASK +AMIATLLDQKF-NTAIPAKLPKDVKVAHKTGSVT-GVRHDSGIVFLPDGRKYVLILLSKD +IK-DDNATLGVMATLSEWIYQY- +>[subseq from] Class A beta-lactamase n=1 Tax=Muribaculaceae bacterium TaxID=2498093 RepID=A0A4S4H4G5_9BACT +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLVLTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKNRMTIRELLEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQLYS +EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSVAVFVAD +SNYDIATTSAIIAEVSKIVLE-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf17 TaxID=1735683 RepID=A0A0Q4FL37_9SPHN +-----NAVQALGSSFQGQVGIAVRDVTDGWVV-GYNADAAMPQQSVSKLWVAIAVMDAVD +RGALSLSDAVTVRQSDLTVHQPIRARVGADGTTVSALLDCAMTRSDNTCNDVLLWKVGGP +TAIRRMLTAKRIAGVSFGPGERVLQARYLAAPYDGASANGITLGLALLQRGELLSNASTV +HLLTVMGASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLRSPDGHTYAIAVLIGS +TRRPIPARMQFMGNVTRAVIQ-- +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. ZYM-1 TaxID=1681184 RepID=A0A0P7N290_9BACI +----EKMIQDMIQETPYKVHLFVKNPKTEQFLyRYQMEESFSSASVIKVPILLAVLAYIE +KHSLSLHSSLSISPDDWVDYSVVSEQRLTQ-STFYELLVWMIITSDNTATNVLIDVV-GM +EYLNDYFRQIGLQETLLQRKMMDVDR-LAKGIDNFTSPRDMAHLFTRIYQQDLVSSPYSE +LAIDILSRQRV-SDGLKRYLVDDVKLAHKTGGLET-VNHDVGIVYSSAVD-YIIGIFVTN +VT-DNNQARQLIGRLSKVVYAH- +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Blastopirellula retiformator TaxID=2527970 RepID=A0A5C5UWF4_9BACT +--DLAEALLPALKRHRGEAAVVIKHLPSGATF-AFHGDRPQSTASLIKLPLLMALYQAVN +EKQVTLDALVEMKKEDQVPGSGILTGHFSPGLSVRDAAHLMVTYSDNTATNLVIDQV-GL +PATRKLMKTLDCPSTQLNSKVFRRDTSSKQYGLGVTSCDDMIRLLELLHKGEFIDKATSQ +AIIDQLAFVND-KSKVTRFLPPGVKPAHKTGAVND-ARTDAGIIPLPEGA-LLFCVLTQQ +NEGDKNEAELLAAEIGQVAYHYf +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Blastopirellula retiformator TaxID=2527970 RepID=A0A5C5UWF4_9BACT +---------------------TVIDLDSGKTLgGDNADGVRDPASVTKIMTAYLVLQMAE +ESPELLDEIVTFSQRADKTPGSTSGLKVGEQVSVGELLYGLMLPSGNDASVALAEHFGDV +AAMNSQAEKLGMTQTGYANPHGL------TAKGHVTTAADMAKLGRAAMQLERFREIVAT +PQRGATVESKTGYQRTNRLLHQEGYFGVKTGTTGQAGACLVSCCERDGK----------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Emticicia oligotrophica TaxID=312279 RepID=UPI00025F57BC +--ATKTAIEAKLKAVDGVFAVAFKDLQTGKTL-FINEKENFHAASTMKTPVMIEVFKQAK +AGKFKLTDSILVKNESIVDGSPYSYKQIGKKMTIYDLTYQMIIVSSNLATNILIDLV-DA +KNANQSMRALGAKDIQVLRGVEDQK-AFDKGLSNTTTAYDLMLIFEKIAENKVIDKKSCE +EMRKILFDQKF-NEIIPEKLPKTVKVAHKTGSIT-GVQHDSGIVYLPDGRKYVLVLLSKK +LK-NADAGVKVLAEVSEMIYE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides caecimuris TaxID=1796613 RepID=A0A1C7H504_9BACE +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKNRITIRELLEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS +EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD +SNYDIATTSAIITEVSKIVLE-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf23 TaxID=1735689 RepID=UPI0009E93EE0 +--DLLNAVQALGAGFEGQVGISVRDIDENWVV-DWQGDIPRPQQSVSKLWVAIGVMDTID +RKRMSLVDPVTVTRADLTVHQPIRTVVGKAGTTVGDLLRGAMTRSDNTANDVLLWRIGGP +AAVNRMLKDKRVAGVRFGPGERQLQARYLEAPLDGASANGVTLGLSLLAQGRLLSDRSTT +SLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS +TRQPIPARMRLMGDVTRAVIA-- +>[subseq from] serine hydrolase n=1 Tax=Nostoc sp. UIC 10630 TaxID=2100146 RepID=UPI0013D6FDD5 +--ELKTPIKALMARYRLTPGIFFMDLKTGDYF-SFNGGKAFSAASTIKYPILIALFQEVD +AGRIKLGETLVMRRKHVTGGSGNLQQRVGTKLSLLQTATKMMTISDNTATNMIIDRLGGV +SKLNQKFRRWGLQSTVIHNMLGDFKGT------NKTSAKDLVRLSALVTNNQLISDRSQS +QVLGIMIRCQN-RKLLPSGLGSGANIAHKTGTLRF-ILGDAGIIETPSGKRYLAGIFVRR +PNND-IRARDFIRQVSRVMYGYf +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6HPT9_9BACT +-eKLDARAGEMVERFEGVMGVAIVDLTDGRAI-LQNADRVFPTASSIKIAILLELYRQEQ +QGKAKLDDVYTFDPKDLVEDSQIMAGLTAGVVTNRDLAQFMIAVSDNAATNVLIDRV-GM +QNVNAMLRNFGLTKTMLRRKMMDIAAAKRG-DENVSTPQEMARLLETIHKGKALSTELTA +GFIKQLKTLKK-DSYLSYELPPGVEIADKPGSLD-GVRTDSGIIFAKNR-PFAISVMTAY +DR-DERAAEHAISEVALEAFRYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D6UQS7_9SPHN +-rELDQAVSRIGGTFXGHVGIAVRDXEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD +AGRLXLSEMVAIRTADLTVHQPIRDIVRRDGSDYAELIERAXTESDNTANDRLLRRVGGA +XXVQDFLDTHGLASIRFGXDERSKQSSYLADPIDGAPPVALVEALARXQRGELLSAGSTG +LLLGTLARTKSGPQRLKAGAPEDWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR +TREPTPVRMEMMQQVVRAVAR-- +>[subseq from] Beta-lactamase n=1 Tax=Stigmatella aurantiaca (strain DW4/3-1) TaxID=378806 RepID=E3FNK7_STIAD +-----ELLQQISQVKGGTVAVAYRDLGDSRDAvFLEADTSFHAASTMKVPVMIEFFRQVD +AGVLALDQPIVLTNRSIVDGSPYSYEHLGRPMPASELLKRMITRSSNLATNSLIALV-GA +KRVTRTLRTLGAPSMTVLRGVEDGK-AYAKGLNNTATARDLATLLAALEQGKAASPRSTQ +AMRDILLAQEL-NALIPAGLPPGTPVAHKTGQIT-AVLHDAAIVYPAGRAPYVLVVLTRG +IA-DEQVARALIVDLSRSVHA-- +>[subseq from] Serine hydrolase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A326GFP8_9SPHN +hqALQSELVAIDGAFAGDAGIAVVEVASGAVM-QSDGRVPFPQQSVSKLWVAMTALDLVD +KGKLGLQEPVSIGRQDLTLHQPIRAIVLEHGTNFGELLHRAITESDNTANDRLLLRVGGP +QAVEGYLRRQSISGVQFGTDERTKQSAYLADPIDGASATGMATALARLARGELLSGPSTR +LLLGTMAQTKSGPNRLKGSVPEGWSMAHKTGTGQQSGYNDVGILTAPDGTQFAIAVLIGS +TRSSYAERFAMMQAVTSAVVRY- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. CAG:487 TaxID=1262928 RepID=R5PW78_9BACT +--SLAERIDSILSGRRMTVGVSAEC-GDFSYV--RNARVRFPLMSVFKVHVAMKVLADMS +ASGTSLDTVVHVERAMLREYSPLRDARPSGDITLAGLMRYSVAESDNNACDILIRMAGGI +GQVDRYVRSLGVDGFRLMHDEDAMHRDITRCYDNWSTPEAMTRLMKIIFEGSA---PLYA +PLRSMMAAIVTGADKIRAGVPESLPVAHKTGSSDKTGDNDVAVVRMPSGRNCYITVFIKD +SAETDAVNAAVIAAVAREIVE-- +>[subseq from] serine hydrolase n=1 Tax=Paucisalibacillus globulus TaxID=351095 RepID=UPI000A00D08D +--NLTERIRRIMEAAGGTWGISLHDLDTNETW-EFNAHELFYSASVIKIPIMIAVFAASH +RKEISLSNCLPLKREDMVGGSGVLQHMTPGTITIYDLITLMIIQSDNTATNILIDLV-GT +EAIQQSLKEMGLEKSKFYHKMMTQDAN--REGLNEITAHEMTNMLKELATGKIISVHACE +QMIDRMKKQQV-RNSLPANIPKQWEIANKTGNIS-GVRHDVGIFYVGKR-TLIASILSRG +VD-D-LKSAA------------- +>[subseq from] Serine hydrolase n=1 Tax=Larkinella sp. ZZJ9 TaxID=2315727 RepID=A0A368JSE3_9BACT +--------------AQAQVNVAFESLVDGTQF-VHRPDELAPSASVIKIPIMIETMEQVK +AGKFDLDKIHVLLASEKTGGSGVLQTYPDESITNLEVLTLMMTRSDNSATNILIREL-GM +DNINRRMQTLGLTQSRLNRVMMDTLAA-KQGRENRVTAREMNLLLKKIYRNEVATPALCA +QMIDILKRNAD-QTTFRLFLPKSAVIAHKTGELTY-VRGDAGIFYVT--KPFLLSIFVQG +TT--TPEAEKIIGEIAAICYNQy +>[subseq from] serine hydrolase n=1 Tax=Clostridium peptidivorans TaxID=100174 RepID=UPI000BE3CF99 +----DQKLYSILGTLEGEVGIYFEDIQTGEKI-LINPDSVFSAASTVKIPLVSLLFQEVS +EGKINLNDIIELSEENRVGGTGIIKNLDKRYPTVLDLATLAIIVSDNAATNQLVDLVGGL +EGITKYCDSIGLTNTKFQRKMMDIKAK-ASGKDNLTTARDMGNILAKLARNEIVSANASR +QIVDIMKSQQL-RSKLPAYIPAIVMVANKTGDLDR-VQHDVGIFILPGNNYYILTMFTSN +LSAD-SEGIRAIGEVSKAIYEE- +>[subseq from] Serine hydrolase n=1 Tax=Chamaesiphon polymorphus CCALA 037 TaxID=2107692 RepID=A0A2T1FWF8_9CYAN +---LKSQIKTLAAKYSISPGMFFMEVDTGNYL-DINGEKSFPAASTIKLPILMALFQAVD +SGQVKLDEKLTVRRDLITGGSGELQNSRGAKLSVFQTATKMIAISDNTATNMIIDRLGGR +KVLNSKFKSWGLRKTVINRMLGDFKGA------NTTSPADLVRVSALLAKRQLITETSRS +KVLDILNQTAN-RKLLPAGLGKGAAIAHKTGTLGR-LIGDAGIIEMPNGKLYLAGIFVKR +SFND-VRARNFVQAVSKLTYNY- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6JD60_9BACT +-kKLELRIDEIAMLFDGVMGIAIVDLTDGRPAlLRNAEHVFPAASSIKLPILLELYHQDE +KGKATLDDLYTVDPKDLVEDSRVMGGLSAGVVTNRDLAQFMVAVSDNTAANVLIDRI-GK +DNVNATLRGLGLTKTMLRRKMMDVTAAQ-RGDENVATPHEMVQLLEAIYKGKVLKADSTK +QLIKQLSTLKP--SYIPRDLPDGVQVANKPGELE-GVRTDSGIVFSANR-PFAISVMTAY +AS-DERAAERAISDVAREAYHYf +>[subseq from] Serine hydrolase n=1 Tax=Larkinella sp. ZZJ9 TaxID=2315727 RepID=A0A368JS31_9BACT +-eQLRQQIEAQLAKQPGRFAVAFKDLTTGQEL-LIHEREEFHAASTMKTPVMIEVYKQAT +QKRFSLSDSILIKNESIVDGSPYSYTKVGTKLPLSAVMYDMIILSSNLATNLIIERV-DA +KKVMQTMREMGAKDMQVRRGVEDTKA-FQQGLNNTTTAYDLMVLFEKIATGKAVSPEASQ +DMIRILLDQRF-NSVIPAKLPKNVKVAHKTGSITS-VRHDSGIVFLPDGRQYVLVLLSKE +IKSD-AAVIESLATVSGMIYQYf +>[subseq from] Beta-lactamase class A n=1 Tax=Allonocardiopsis opalescens TaxID=1144618 RepID=A0A2T0QA86_9ACTN +---------------------------------AHRPDQVMPTCSVFKSFLVAALLHDRD +DREYWYDAAIDYDESDVVINSAVLSERSG-PISPHDLAEAALRYSDNTAANLLLAELGGP +AVLTEFTRSLGAAVTRFDRLEPELNAAVPGDDRDTSTPAEVAMLMHAVLVERSAGAYTAA +RLNTWMLWNET--SRITEALRTGDELTDRTGAGAYGVVNDAGVLYRPGQPPRSFAVMTRT +DDEDAENDDAVVLEAARLL---- +>[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127STV8_9BACT +-------------------------------V-SVNNMYRYPMMSTYKFHQALSVVDYLH +KHDKNLATEILVKKSDLLAHSPLRDANPNGNITVGDLLKYSLIESDNNACDILFKYIGGP +LVTEKYIHGLGIKDVAISQTEAKMMESEDNCMLNWTKPSAAVLLLETFLQNQMFSKNEVL +FLERAMADCKTGNNKLKAGLPKQVLFAHKTGSSGRNADNDMGFVVFPNGQYYTIAVFIMN +SRETDQENAKIMADISRTVYEYf +>[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SQ09_9BACT +-kTIEKALLEYVSDKDARIGIAVI-VNGTDTI-SINGKRYFPMMSVVKFPLALTVVQWID +ANGLSLNDSIAFSEKALKEYSPMLKRYGKKRMTVRELLEWSLVESDNNAADILLNHVGGI +SGATKIMRKIGVDNIEIGASEDDMHRDPYLSYLNRTTPLAMAQLFNRFDAEMRNTSLSYS +EIATMLEQCRTGIDRLVALLSSDATIGHKTGTGFISAINDCGYVNLPNGVRYSIAVFVAD +SGYDMAGTSAIIAEISRIVW--- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. ABOLE TaxID=1985878 RepID=A0A430EL96_9SPHN +--ALLNAVQALGAGFHGQVAISVRDVDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID +HARMTLATPVTVTRSDLTVHQPIRPLVGPNGTTVGALLECALTRSDNTCNDVLLWKVGGP +TAIRRMLKEKGVDGVGFGPGERELQARYLAAPYDGATANGVTLGLSLLAQGKLLGRTSTD +RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS +TRQPIPVRMRLMGDVTRAVIR-- +>[subseq from] serine hydrolase n=1 Tax=Citromicrobium sp. JLT1363 TaxID=517722 RepID=UPI000225EB75 +---FERQIATLADGSNGRIGVYAIDLATGEEV-GILADQRFPMASTSKVAIAATFLAGVD +QGRWSLTSEFELPG-------------RGTYISGREHLDLMISRSCNDCTDALLNAVGGP +QAVNAWMRQAGIYDFELTRDIATLVRASEIAFEDSATPRAMGRLLAGIYQGKWLSSYSRQ +VLMNAMASTVTGKRRMTSALPDSANLAHKTGTLSR-TASDIGIFYTPDGRPVAAAIYVTG +QSVSMASEN-------------- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000B9595A2 +------------------------------------------------------------ +----------------MVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Gloeobacter kilaueensis JS1 TaxID=1183438 RepID=U5QHF3_9CYAN +--ALEAAMHKLTQQPRLRSGFLFFDPATGAYA-QMAADESFSAASVIKVPVLVELMRQVD +GGSVRLDEVLTLKAAHKGGGSGWLQYRPNGTMSVLAVATLMIIRSDNTATNMIIDRLGGA +AYLNEQFRRWGLRRTVINAPLPDLEGT------NTTSPGDLALLMSELDRGELTSPQGRT +VAYGLMGRTRI-GSLLPMGLGPGARILHKTGDIGK-MVGDVGVVTTPDGRRYLATALVER +PHND-RRANQLIAKLSQAFYHVf +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' 232 TaxID=2014531 RepID=A0A235IQQ0_9NOSO +--ELKTPIKALMARYRLTPGIFFMDLQTGDYF-SFNGDKAFSAASTIKYPILIALFQEVD +AGRIKLGETLIMRRKHVAGGSGDMQQRVGTKLSLLQTATKMMTISDNTATNMIIDRLGGA +SKLNQKFRTWGLQSTVIHNMLGDFKGT------NKTSAKDLVRLSALVTNNQLISDTSQS +QVLGIMIRCHN-KSLLPSGLGSGANIAHKTGTLRF-VLGDAGIIETPSGKRYLAGIFVRR +PNND-IRARDFIRQVSRVMYGYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. EC-SD391 TaxID=2038398 RepID=A0A5E7YBE9_9SPHN +--DLLNAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD +RGQMSLADPVTVTQSDLTVHQPIRALVGPDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP +VAINRMLAAKGIAGVTFGPGERHLQARYLAAPIDGASSNGVTLGLSLLAQGKLLSARSTT +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAIAVMIAS +TRKPIPARMRLMGDLTRAVVA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax cattleyae TaxID=80868 RepID=A0A1H0V480_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +QRVQAVARALDLKTSELQATMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ +MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQEGARAIVVATCAE +GMDEMRQAGRLFEQIGRAITR-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=D1LFI8_9BACT +------------------------------------------------------------ +-----LNQPVEIKPADLVNYNPIAEKHVNGTMTLAEVSAAALQYSDNTAMNKLIAQLGGP +GGVTAFAREIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSW------------------------------------ +----------------------- +>[subseq from] Penicillin-binding protein, transpeptidase n=1 Tax=Calothrix sp. PCC 6303 TaxID=1170562 RepID=K9V0Y7_9CYAN +---VSSQVKSLMNRYSLDPGIFFLDLQTGNYI-DFNGEKAFPAASTIKFPILIALFQEID +AGRIKLNETLVMRRNLITGGSGNFQYKPAGSFSLLETATKMITISDNTATNMIIDRLGGK +AKLNPKFRAWGLQNTVIRNLLGDFKGT------NTSSPKDLVRLSALIANNQLLNDRSRN +RVLDIMRRVEN-QSLLVSGLGKGTIIAHKTGTLGI-VLGDAGIVQTPSGKRYLAGIMVRR +PFGD-SRAKSFITQVSRLVYG-- +>[subseq from] Uncharacterized protein n=3 Tax=unclassified Candidatus Omnitrophica TaxID=1047005 RepID=A0A1G1Q060_9BACT +-----------IADFRGNIGIVIKDLNEGWEI-DFNKGALFPSASLVKVPILLSYFYAQQ +EGKVRTSDLVSLKSYEKVPGSKVLGDSSVGSFSVEELFEPMIAKSDNTATNILIDLL-GF +EAFNDYFIRLGLRNTNLVRRMMDFEER-KEGRENYTTAEDMAYLLEILYRRSFLDKNTSE +KCLGFLKQQKI-KDRIPRKLPEGVTVAHKTGLENY-ICHDAGIVFTQKGD-FLICVLTKH +QDKFAAPAKRFISDIALITYNYy +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000A100C18 +------------------------------------------------------------ +----------------MVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIIKEIGGI +KTIKKRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. animalis TaxID=76859 RepID=A0A2G9FA65_FUSNU +-tEWKKEIEKIISRVKGSVCINFYDLAKNNGF-SINGDKKVLSASMIKLLILAELVKKVS +ENKFSLSDAITVTEAMKTGGDGVLKELNSEHFTLKELATLMIIVSDNQATNILIDFL-GM +KNINQLGREVDLKETFLGRKMMDIEAR-KKGYDNYTCADDISSLLKLIYQEKLINEEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGNKA-YILVVLTSG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KF98_9BACT +------AIREIVRPLKAHVGVSAVMLDTGESV-SVGDEAFYPMQSVYKFPLALSVLKRVD +QGVLDLDQKVKVTRDQLPEWSPLRDRFPQGGFPLKELLRFSVQESDNNACDILFSLIGGP +ANVQKDLKEWGVENMNVKYTEADTHRNHEWQYSNSARPTAMTSLFRMFDEGKILKKDTQL +FLWDMMASCATGAERLKGLLPKEYVVAHKTGTGGT------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Emticicia sp. CRIBPO TaxID=2683258 RepID=UPI001412FCA0 +-eQLRKEIESRFKSVEGDFGLAFKDLQTGATL-LIREKETFHAASTMKTPVMIEVYKQAG +EGKFKLTDSIVVKNESIVDGSPFSYKKIGQKMTIYDLTYQMIIVSSNLATNILIDLV-DA +RKANETMRKMGAKDIQVLRGVEDDK-AFQLKMNNTTTAYDLMLIFEQIALKKAVSKRSSE +EMIKVLSDQKF-NEIIPARLPAGVKVAHKTGSIT-GVQHDSGIVFLPDGRKYVLVLLSKN +LK-DKDKGVAMLADVSALLYD-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobium limneticum TaxID=1007511 RepID=A0A5J5HSQ7_9SPHN +-----NTIQALGAGFNGQVGISVRDIDEGWVA-AWEGDIPRPQQSVSKLWVAIGVMDAVD +RQRLSLTDPVTVTRADLTVHQPIRTLVGKTGTTIADLLHGAMARSDNTASDVLLWRIGGP +AIINRLLGDKGIGGVRFGPGERQLQARYLAAPLDGASANGVTLGLSLLAQGKLLSPQSTA +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS +TRQPIPVRMRLMGNVTRAVIA-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A649UH73_PSEAI +---FKTDLEKLESEKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID +SGTERGDRKLSYGPDMIVGWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP +AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMAGTVAKVLYGGALTSTSTH +TIERW------------------------------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Aquincola tertiaricarbonis TaxID=391953 RepID=UPI000614A0C0 +--RLQAELAQVAQRHSARIGVYVRDLDSGASA-SFQADRPWYLASTVKVPVAIAVLRGVE +RGDFGLDTPLTLRAADLVDGAGPTRKPLGAPLTVRYLLEQMIVWSDNTASDMLIGLV-GI +QAVNALVQELVPGGFERITSLADVRRAYYATGLNTGRLDAYGELLARLVEGQALGPKGTA +WLLRLMERVKTGPNRIKAGLPTRARFAHKTGTQR-GRTCDAGVISVPGKDSRVLVAACTS +GELSVARSDRALREVGAAIC--- +>[subseq from] serine hydrolase n=1 Tax=Gloeobacter violaceus TaxID=33072 RepID=UPI00030E8212 +--SLESAMLKLTDQPRLRSGFMFVEPASGRYV-AMADGESFSAASVIKVPVLVEFLRQVD +SGRLKLDDTLILRQEHKGGGSGWMQYMPNGKMSAYNVARLMIVRSDNTATNMIIDLVGGA +DYLNAQFGRWGLRTTRINAPLPDLEGT------NTTSPADMALLLTELERGRLVTTQMRA +KGYELMGRTRT-GSLLPVGLGPGAKILHKTGDIGK-MVGDAAVVTMPDGRRYVAVALVER +PHND-RRANQLIAKLSQKFYYV- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=D1LFH2_9BACT +------------------------------------------------------------ +-----LNQRVEIKKSELVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWV----------------------------------- +----------------------- +>[subseq from] Extended spectrum beta-lactamase VEB (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1U9YG06_KLEPN +-----------------------------------------PMQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +S---------------------- +>[subseq from] serine hydrolase n=1 Tax=Acidovorax cattleyae TaxID=80868 RepID=UPI000B88F911 +------------------------------------------------------------ +----------------------------------------------------------GP +QRVQAVARALDLKTSELQATMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ +MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQEGARAIVVATCAE +GMDEMRQAGRLFEQIGRAITR-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Citromicrobium TaxID=2630544 RepID=A0A0P7A0T1_9SPHN +---LDDQLFALGTGLKGKVGIAVYDPARGRMM-HFKGTQLYPQQSVSKLWVALSALDMAD +AGRLDLSETATVRNGDLAVHSPIRQSVAAQGTSYADFISRALTQSDNTANDMVLRRVGGS +DAVRRVLARKGFADIRFGPGERPMQSAYVDDPVDGASPVAIASALARLESGELLSDASTT +RFLGWLGEVKSGPNRLKGGLPDGWSIAHKTGTGQQAGYNDVGILTAPDGSVYTVAVMIGR +TQVPIPVRMEMMHGVVRAVAG-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodohalobacter sp. SW132 TaxID=2293433 RepID=A0A371QTQ1_9BACT +------------------------------------------------------------ +-------------------------------------------------------RLRGI +SNMSERLDEL-VRIMDVDRDELNAENKYYDGGLNSGTMEAMSVMLERLVEGEYLNEENTD +LLIEIMEVIATGDHRIKAGLPEGIRFAQKTGTLI-GRACNVGVIYPQDQKPIVVSVCAKD +YN-QLSDAENAFQRIGMVISENw +>[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides sp. TaxID=29523 RepID=A0A351YGJ7_9BACE +---LQDDVEDYLEDKQATVGISVL-TDTCTIL-AVNDTTRLPLLSVFKFPVAWAVLHRIE +RHGTPLDTVFHLTPDDLKTYSPLCMSHPDRTVRMDSLLFYSVALSDNNACDVLLKYAGGP +KAVERYIHDLGIADISLSATEDDMHREPSKALDNNATARAVSQMFQRFMQRDTLGTAHHN +FLFRTLTATSTGNNKLRAGIPRHQMFGHKTGSSDRTADNDAGFVVMPNGQRYYITVLVNN +SMENDSVNAAIISTVSQMTYD-- +>[subseq from] Serine hydrolase n=2 Tax=Sphingomonas TaxID=13687 RepID=A0A0W1QM95_9SPHN +----VNRLADLAHGFEGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD +QGRIRLEDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP +PAVRSFIARNALGPIRFGPGEKLLQLSYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ +WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD +TPRPINERQLLMQGVVRAIVA-- +>[subseq from] Serine hydrolase n=1 Tax=Peptoniphilus grossensis TaxID=1465756 RepID=A0A1U7LZN2_9FIRM +-nKLKDEVKNIINESFFNVSISFCDLDNGEHF-SVEGDKRMQSASMIKLLIMLTLLKKVE +EGEISLDEKIKLEKEKRVEGSGILKELSYDHFSIRELLTLMIIISDNFATNILIGKI-GM +DEINRTAKDFGLKKTILQRNMMDLDAK-ERGLDNYTSSDDILKILKSIYEKNFLGEDMSK +LAIDILLKQQE-RDRLQRYLKEDLKIANKTGDLDN-LENDGGIFFTENK-NYILVVLVNQ +AKS-NILAKELIGKISLKIYN-- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus formosus TaxID=54913 RepID=A0A220MDE8_9BACL +---LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY +AGKFALEDKIKLRAEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT +ESIRNVMQKTKMTNSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRHLATGKVISYDSCL +KMVAILKAQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG +LE--QKDAANVMAQIGNLVYHGy +>[subseq from] Beta-lactamase class A n=1 Tax=Psychrobacillus sp. OK032 TaxID=1884358 RepID=A0A1H9X2R0_9BACI +-kALSNKINDLIGQSKGTWGIVLEDLDVGEKW-ALNENELFYAASVIKVPLMVAVFSAVE +RGEIALTDQIILKEEDIVGGSGVLQHLTQETFSLQDMIMLMIIQSDNTATNILIDQV-GV +EHIVQTMKEVGMDKSTFYNKLM-MNRPNPK-GFNRITASEIAKLLKLMATGELVSADASK +QMLDIMKKQQI-KDCLPAKLPTAWELAHKTGWIP-GTRHDVGIFYVGQRK-LIATVLSKG +VD--DLVSKRVLADTGEVIYNY- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6CCB7_9BACT +-kKLEARVDEIAERFDGVMGVAIVDLMDDRAI-LKNADHVFPTASSIKIAILLELYRQEQ +QGKAKLDDIYTFEAKNLVDGSQIMTGLTPGVLTNRDLAQFTVAVSDNAAANVLIDRV-GM +QNVNATLRNLGLTKTMLRRKMMDIAAARRG-DENVSTPQEMMRLLEAIYQGKALDKELAK +AFMKQLSTKKE--SYIPRQLPPDVSIANKPGDLD-GVRTDSGIVFAKNR-PFAISVMTTY +DRE-ERAAESAIAEIALEAFHYf +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium pseudoperiodonticum TaxID=2663009 RepID=A0A2D3PPH5_9FUSO +-tEWKKEIEKIISEVKGQVSVSFYDLDKNIAF-SIDGNKKVLSASMIKLLILAELMRQVS +EAKLSLSQKIILTDSMRVGGDGILKVLDSGHFSLKELAKLMIVVSDNEATNILIDLL-TM +ENINALGRNLALKETFLQRKMMDSNAK-EKGYDNYTSSDDIALLLRLIYEGKLINEETSE +IILDILLQQQQ-SERLQRYLPSDTKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTSA +MS--NLECRETIGKISKYIYDK- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1W6RZ34_9BACT +------------------------------------------------------------ +------------------------------------------------AMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPK------------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf28 TaxID=1735695 RepID=A0A0Q4JQP8_9SPHN +--DLLNAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD +RGQMSLADPVTVTRSDLTVHQPIRALVGPDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP +VAINRMLAAKGIAGVTFGPGERHLQARYLAAPIDGASSNGVTLGLSLLAQGKLLSARSTT +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAIAVMIAS +TRKPIPARMRLMGDLTRAVVA-- +>[subseq from] Uncharacterized protein n=1 Tax=Geosporobacter ferrireducens TaxID=1424294 RepID=A0A1D8GP08_9CLOT +---LEKEIIRALESTSAKTSVVLKDLRNDIWIfQKEEKMVIPSASTIKILIMTEALNQIQ +QGKYQLEEKVSIMEEEKVPYSIISDL-TTDFYTFQDLITLMIIVSDNTATNVLIDLL-GF +DAINEMATKIGLKNTQLKRKMMDFEAA-QMGRQNITTAIDMAMLMEKIFNREILNEKLCN +HAIDILKRQKD-KIMLKRYIPEDTVIAHKTGDLAN-LNHDIGIFYLPQQT-YLLGVFVTE +AQ-SNLAAQQIIGEISKLVYTYy +>[subseq from] AMIN domain-containing protein n=1 Tax=Calothrix sp. PCC 7103 TaxID=32057 RepID=UPI0003734E22 +--QLSSQVRSLMSRYSLDPGLFFIDLETGNYV-DYNGEKAFSAASTIKFPILIALFQEID +AGRVKLNETLTMRRDLVTGGSGTMQYRAPGTFSLLETATKMITISDNTATNMIIDRLGGR +NKLNPRFRTWGLQNTVIRNLLGDFKGT------NITSAKDLVRLSALVANNQLLSNSSRV +RVLDIMRRVEN-TSLLASGLGRGATIAHKTGTLGV-ILGDAGIIQMPNGKRYLAGIFVRR +PFGD-ARGREFISQVSRTVYS-- +>[subseq from] serine hydrolase n=1 Tax=Spirosoma sp. I-24 TaxID=2666025 RepID=UPI00138E8958 +--------TAYIHRLNARISIATKSLADSSLSfYERADERVPSASVIKLPIMIEAMERVK +AGTLDLDEIHILTDSEKTGGDGVLKTYSHRSVSYRDMLRLMMVFSDNTATNIFINEL-GR +DAINQRIHQLGLAQSQLNRVMMDTLAA-RQGRDNYVTAREMSQLLEKIYRKQVATPELCD +QMIDILKQNED-TKTIPGLLPKGTVVAHKTGTLTY-VRGDVGIVYAKSGQPFLLSVFVEG +VA--QPEAERIIGEIALICYTYy +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6BYB5_9BACT +-kKLEARVDEIAQRFDGVMGIAIVDLTDERAI-LKNADQVFPTASSIKIAILLELYRQEQ +QGKAKLDDTYTFDAKDVVDGSQIMTGLTSGVLTNRDLAQFTVAVSDNAAANVLIDRV-GM +QNVNATLRNLGLTKTTLRRKMMDIAAA-KRGEENVSTPQEMTRLLEAIHKGKALDKELAN +AFMKQLSTKKE--SYIPRRLPPDVDVANKPGDLD-GVRTDSGIVFAKNR-PFAISVMTAY +DR-DERAAEGAIAEIALEAFHYf +>[subseq from] Beta-lactamase n=1 Tax=Rhodobacterales bacterium 12-64-8 TaxID=1970554 RepID=A0A257Y7R8_9RHOB +----VERFRAIADYVAGRLGVCAIDTGNGRTL-GTNTNGRFAMASTFKWLLAAAVLKRHE +AIPTILDQTRRVEEKNLLDYAPVTS-VIAGKLSLAELCSAAVSVSDNTAANLLLSHLGGP +AALTQFLRESGDTVTRLDRTEPTLNENAKGDPRDTTTPAEMAQTMARLLTDEVLNAASRA +RLIGWMRASTTGTACVRACLRSGM------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Citromicrobium TaxID=72173 RepID=UPI000C1B9BA3 +---LDDQLFALGTGLKGKVGIAVYDPARGRMM-HFKGTQLYPQQSVSKLWVALSALDMAD +AGRLDLSETATVRNGDLAVHSPIRQSVAAQGTSYADFISRALTQSDNTANDMVLRRVGGS +DAVRRVLARKGFADIRFGPGERPMQSAYVDDPVDGASPVAIASALARLESGELLSDASTT +RFLGWLGEVKSGPNRLKGGLPDGWSIAHKTGTGQQAGYNDVGILTAPDGSVYTVAVMIGR +TQVPIPVRMEMMHGVVRAVAG-- +>[subseq from] Beta-lactamase n=1 Tax=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) TaxID=63737 RepID=B2J9P6_NOSP7 +--ELKTPIKALMARYRLTPGIFFMDLKTGDYF-SFNGDKAFSAASTIKYPILIALFQEID +AGKIKLGEALVMRRKHVTGGSGDLQQRVGTKLSLLQTATKMMTISDNTATNMIIDRLGGV +SKLNQKFRRWGLQSTVIHNMLGDFKGT------NKTSAKDLVRLSALVTKNQLISDRSQS +QVLGIMIRCHN-RALLPSGLGSGANIAHKTGTLRF-VLGDAGIIETPTGKRYLAGIFVRR +PNND-IRARDFIRQVSRVMYGYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V5A0_9BACT +------------------------------------------------FMAASAILKESE +VKKNLLTQHVALKKSDLVNYNPITEKHLNEGTTIGELAAAALQYSDNTAMNKLIEHLGGP +NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRTGLPATWIV---------------------------------- +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=D1LFI7_9BACT +------------------------------------------------------------ +-----LNQPVEIMPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWT----------------------------------- +----------------------- +>[subseq from] Imipenem-hydrolyzing beta-lactamase n=1 Tax=bacterium HR08 TaxID=2035403 RepID=A0A2H5VMZ6_9BACT +-eKTEARLREIVASARGVMGVVVVDLVSGERF-AINEDLVFPQGSAIKIPILMEVYKQAH +EGRFRLTDRRRLEKAHVVGGSGILKEFGEGMLSIYDLCVLMIVLSDNTATNMLIDLV-GM +ENVNRTMASLGLARTRLQRKMIDPAAS-ARGEENLSTPAEAARLMEILYRGEFINREVCD +QILAVLKKPKR--TAVSAGVPSGVPIASKPGSIP-GVSTEWAIVDLRER-PYIIVVMETY +GMG--EDTPATFREISQTVYDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=D1LFH1_9BACT +------------------------------------------------------------ +-----LNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAVLPASWV----------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Gloeobacter kilaueensis TaxID=1416614 RepID=UPI001182E98C +--ALEAAMHKLTQQPRLRSGFLFFDPATGAYA-QMAADESFSAASVIKVPVLVELMRQVD +GGSVRLDEVLTLKAAHKGGGSGWLQYRPNGTMSVLAVATLMIIRSDNTATNMIIDRLGGA +AYLNEQFRRWGLRRTVINAPLPDLEGT------NTTSPGDLALLMSELDRGELTSPQGRT +VAYGLMGRTRI-GSLLPMGLGPGARILHKTGDIGK-MVGDVGVVTTPDGRRYLATALVER +PHND-RRANQLIAKLSQAFYHVf +>[subseq from] ClassA (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SAX3_9BACT +------------------------------------------------------------ +-ENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATDQLLKKFYKNEILSKNSYD +FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] Serine hydrolase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E2NIX0_9SPHN +---LDDQLFALGTGLKGKVGIAVYDPARGRMM-HFKGTQLYPQQSVSKLWVALSALDMAD +AGRLDLSETATVRNGDLAVHSPIRQSVAAQGTSYADFISRALTQSDNTANDMVLRRVGGS +DAVRRVLARKGFADIRFGPGERLMQSAYVDDPVDGASPVAIASALARLESGELLSDTSTA +RFLGWLGEVRSGPNRLKGGLPEGWSIAHKTGTGQQAGYNDVGILTAPDGSVYTVAVMIGR +TQVPIPVRMDMMHGVVRAVAG-- +>[subseq from] Beta-lactamase n=1 Tax=Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131) TaxID=190304 RepID=Q8RIK5_FUSNN +-tEWKKEIEKIISQVDGKICINFYDLDKKNGF-SINGNEKVLSASMIKLLILAELMKKVS +ENKFSLSDTITITNFMKTGGDGVLKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINFLGKELGLRETFLERRMMDAEA-SKNGYDNYTSADDISLLLKLIYQEKLINKETSQ +LMLDILLRQQQ-GERLQRYLPPDIKIAHKCGDLDN-LENDGGIIWLGNK-IYILVVLTSG +MS--NLQCRQTIGKISKFVYDK- +>[subseq from] Serine hydrolase n=1 Tax=Scytonema hofmannii PCC 7110 TaxID=128403 RepID=A0A139XFB0_9CYAN +---LYPQVKKLMSRYSLAPGMFFLDLETGNYL-DIYGEKVFPAASTIKYPILIALFQDID +AGKVKLNDTLVLRRNLKAEGSGVLQFKPAGTLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSVMIDNDKLLSPTSRS +KALSIMRRVQN-RRLLPSGLGKGATIAHKTGTLGI-ILGDAGIVELPTGKRYLAGIFVKR +PFGD-TRAREFISQVSKLVYG-- +>[subseq from] Uncharacterized protein n=1 Tax=Omnitrophica WOR_2 bacterium RBG_13_44_8b TaxID=1801836 RepID=A0A1G1MM88_9BACT +-qELQQRIKAEISQFKGEAGIVIEDLEAGWEF-SYDKAKLFPSASLAKIPLMAACFLAAD +QGRIKLERNIALKSSDKLTGSGVLKDMPAGTFSVERLIGLMIYDSDNTATNIVTNLA-GI +DYLNSAFKSFGLKNTDLSRKIADYQSR-DKGIENYTTAEDMALLLDKIYRRSLGNKNVSD +QCISMLKLTRM-NDRIPKYLPVAITIAHKTGLEK-GVCHDAGIVFTNKGD-LIIVVLTKH +ANPNSVPSKAFIAKVSLHAYKY- +>[subseq from] Serine hydrolase n=1 Tax=Spirosoma sordidisoli TaxID=2502893 RepID=A0A4Q2UJY6_9BACT +--------------ASARVSVAVESLADSSVSfAHRADERVPSASVIKLPILLEAMERVK +AGTLDLDEIHILTDAEKVGGDGVLKTYSHRSIAYRDLLRLMMVYSDNTATNIFINEL-GM +DAINARIRAVGLPRSQLNRVMMDTLAA-RQGRDNYVTCLEMNRLLKKIYHRQVATPELCE +QMLTLLKQNED-TLTIPRLLPPGTVVAHKTGTLSY-VRADVGIVYA--HQPFLLSIFVEG +LP--TAEAERTIAETARICFTYf +>[subseq from] hypothetical protein n=1 Tax=Spirulina subsalsa TaxID=54311 RepID=UPI0002FE7361 +---LKNRLQSLIARYEFEAGVFFMDLDTGDYV-DIQGSKPFAAASTIKTPILIAFFQALD +AGSVSLTETLVMEEDTRAGEAGDMQQPIGTRFSALDTVTRMITISDNTATNMIMKRLGGQ +DILNQRFAEWGLSATVIRNLLPDLEGT------NTTSAVDLAHVMARVNRGDLVNLRSRD +RLLEIMRNVQN-NQLLPQGLENGAIIAHKTGNIGS-VVADAGLIDTPTGRRYLAAVIIQR +PHND-PKAKDLIRDISREAYQYf +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. EC-SD391 TaxID=2038398 RepID=UPI00125EB4E6 +-----NAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD +RGQMSLADPVTVTQSDLTVHQPIRALVGPDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP +VAINRMLAAKGIAGVTFGPGERHLQARYLAAPIDGASSNGVTLGLSLLAQGKLLSARSTT +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAIAVMIAS +TRKPIPARMRLMGDLTRAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=bacterium TaxID=1869227 RepID=A0A522MX78_9BACT +-sQLQTRLDSLASRAPGSVAVAVRDLRTGQVA-GYNAQASLPAASTIKVPVMVEVFKQME +DGTFTLGREVTLQNGDRDDWGDLAAAPSGSHYTVRRLLWLMITQSDNTAANMLIRLV-GR +VHVNETMRALGLDHTALSDYIRSYGDI----RSIRTTASDMAHLMALIAHGELVDEWSCG +EMLEIMAGQQI-NTLLPEPLPSDVLIAHKTGSLHD-TLNDVGVVYLHDA-PYAIAVMTTR +LP-SLDSGRAFIHAVSSLAFK-- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFOXYB2_FULL_50_12 TaxID=1797969 RepID=A0A1F9X8N7_9BACT +---------ARAEKFPGEAAIVIKDIQTQQEI-GINVARLFPSASLVKVPIMAAVYQAQE +EGKLRLEDHIILKKKHKVRCSRLYNMRPGRKVVIRDIIERMITESDNTATNMLVDAL-GF +GYLNQKFIEFGLKQTDLRRGVMDLKW-RKAGIENYTTAADMALLLEKIYNGELVSHAASA +EMLEVLKRQKV-NDRIPRLLPDGLVIAHKTGLLND-TVSDVGIVFTKEGD-FIICVLTAD +IK-SFLSAKKFIGSVAACAYD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=bacterium TaxID=1869227 RepID=A0A539D5D3_9BACT +------------------------------------------------------------ +---------------DMINHAPVTEQAVGGTLTIQQLMEATVGLSDNPAANILIRELGGL +ERLRAFYRGIGDTDTRVDRLEPEMNRL--DGDKDTITPAQSARNIDRLFVDTPLTAASRT +LLLGWMVATPTGPNRLKAGLPADWRLAHKTGTGGYGPTNDIGLAWPPSGGPLIITAYFHG +ARSTEQQREAAIADATRMAL--- +>[subseq from] class A beta-lactamase n=1 Tax=unclassified Muribaculaceae TaxID=2006847 RepID=UPI001371F84E +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRITIRELIEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQLYS +EISVMLEQCRTGLDRLALLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD +SNYDIATTSAIIAEVSKIVLE-- +>[subseq from] class A beta-lactamase n=1 Tax=Granulicella sp. L60 TaxID=1641866 RepID=UPI00131D05EB +-qSLQQQIQTIAADAHGKVSVACSLPDSPLNC-DLNPTAHPPMQSVFKLPLALTILHQLE +QGKFSIDQPIRFLPEDRILYSSLQDKYPNANVPLRTLLQLTVSLSDNTAADILLRIAGGP +DVVDKYIASLGITGFHLRDGENALHHSVPLQYRNWFEPRSAVQLLRILSDRSPLTPEHTA +QLLAWMRPATP-TTRLQGDLPAGTIVAHKSGTSDAHATNDIGLITLPDGRQLAIAVFVTD +STADTAIREKVIARIARAAYN-- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFOXYA12_FULL_49_49 TaxID=1797954 RepID=A0A1F9VGH8_9BACT +---LMAELQGQAAKFKGDAGILVKDISTGESI-SMNSSKLFPSASLVKLPIMAAVYQAEL +EGRLQLTDKLVLKRSHKVRCSKLYFKRNGTKYEINDLIVRMITESDNTASNMLVEAL-GF +GYINQKFVEFGLKDTDLRRGIMDLKWR-RAGIENYTTVEDMAYLLEKIYNRELVSTAASD +RMMAVLKKQKV-NDRIPRKLPDETIVAHKTGSLRD-TISDCGIVFTQKGD-FIVCVITAD +IK-NYRTAKRFIADIAACAYDK- +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00053A5D14 +--AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAH-------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Glr2387 protein n=1 Tax=Gloeobacter violaceus (strain ATCC 29082 / PCC 7421) TaxID=251221 RepID=Q7NHZ7_GLOVI +--SLESAMLKLTDQPRLRSGFMFVEPASGRYV-AMADGESFSAASVIKVPVLVEFLRQVD +SGRLKLDDTLILRQEHKGGGSGWMQYMPNGKMSAYNVARLMIVRSDNTATNMIIDLVGGA +DYLNAQFGRWGLRTTRINAPLPDLEGT------NTTSPADMALLLTELERGRLVTTQMRA +KGYELMGRTRT-GSLLPVGLGPGAKILHKTGDIGK-MVGDAAVVTMPDGRRYVAVALVER +PHND-RRANQLIAKLSQKFYYV- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas aurantiaca TaxID=185949 RepID=A0A2T5GGQ1_9SPHN +--DLLNAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD +RGQMSLADPVTVTRSDLTVHQPIRALVGPDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP +VAINRMLAAKGIAGVTFGPGERHLQARYLAAPIDGASSNGITLGLSLLAQGKLLSARSTT +SLLTLMHSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAIAVMIAS +TRKPIPARMRLMGDLTRAVVA-- +>[subseq from] Serine hydrolase n=1 Tax=Solibacillus sp. R5-41 TaxID=2048654 RepID=A0A2D1SVL2_9BACL +----KQQLAQLLDQIPYRVHVIIQDYRTNESLiEKNTQSVFSSASVIKVPILMAVLHHLE +KTNGQLSQVVPITSDNVVDFSVLTEQK-QKTATLHELLLWMIITSDNTATNMCIDFI-GI +ETLNYYFQQIGLKSTSVQRKMMDFERQ-QKGFDNVTTARDMQHLFHQIYAGKLLAHEWNE +VALNILLRQRS-HESLKRYLVDDVKIAHKTGGLDT-VDHDVGIVFTEQVD-YFIGVFLTE +VT-DNEKARQYIGQISKIAYAHf +>[subseq from] serine hydrolase n=1 Tax=Cyclobacterium sp. SYSU L10401 TaxID=2678657 RepID=UPI0013D58B7F +-eELEADIQAVIAGTAGDFGVAFSLLDGSETQlLINEKEVFHAASTMKTPVMIEIYKQVG +SGQIALDDSILILNESIVDGSSYSYERIGKKATVYELMYQMIIKSSNLATNILIERV-GA +ENVTQTMRELGAADIQVLRGVEDLKA-FDAGLSNTTTALDMMLIMKAIATGEAVGQEESR +QMMDILYDQYY-KDLIPKLLPETVKIAHKTGAIT-GVQHDAAILTLPDGRSYVLVILTKN +LE-DLPAGKEAISAISKLIYD-- +>[subseq from] serine hydrolase n=2 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD9709F +-hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD +KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAANLLLESFGGP +PALTEFVRSFDDELTRLDRFEPELNEDGPDDLRDTTTPGA-------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Nibribacter sp. BT10 TaxID=2698458 RepID=UPI001366EB5F +--SLKDRISAELSQQKGTFAVAFKDVQTGEEV-LLQEHENFHAASTMKTPVLVEAYKQIE +AGKFTIDSPIEVKNNSIADSSTFSYQHLGKTLPMSDLLYRMIIKSSNLATNIIIELV-GA +ENVTATMRNLGAQEIQVRRGVEDGK-AYALGLNNTTTAYDLMLLYTHLVQGKAVSPAASQ +AMIKILLDQQY-KDIIPAKLPKDVQVAHKTGWIT-GVRHDSGIVFLPDGRKYVLVLLSKQ +LE-DEPAAISAMAQVSLLVYQH- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus okhensis TaxID=333138 RepID=A0A0B0IEU8_9BACI +---LQGCIDEIIHKSTATYGVSIKHLETSEVA-IVNGDKIFQQASVFKIPILVTLLKQVE +SNHLRLDTRVKIKKGDYVPGSGILQELDYGAVSVKDLALLMIIVSDNLATDKLLQMV-GL +DNVQQHMEMLGLKHTTIKHSCYDLLRFERTKKCSVSTANEMNLLLEKLLNYDLLNETNTN +MMLDILLKQRI-QNRLPLLLPEGTKIAHKTGSLDH-YLNDCGIVFLPNDGTYIISVFSSD +HH-STEGGDQEIGEISKAAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium SCN 70-22 TaxID=1660163 RepID=A0A1E4B5U4_9BACT +--SLRERIAARVARHGALAGVYYRDLGSGEEL-AWHADSTFHAASTMKVPVMIAYFRGVD +EGRFGAGQRVTLANRSIVDGSPYAYRRVGEEVAVRELVERMITRSSNLATNVVIELV-GA +ERAQATARSLGASTMMVRRGVEDGLA-FRAGLNNTTTARDLGALFEAIGRGAAASGASTR +AMLEILERQEF-NDEIPAGLPPGTRVAHKTGWIT-GILHDAALVLPEGRPPFVLVVLTKG +IP-DEKVAQRLIADIAGMVWAH- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A3D2PAI2_9BACT +-qTLAEKIKNKLYNFPGNVGLVIKDLKTGKTI-FYNQDKLFPSASLVKIAIMSACFQAES +EGKINFNDYFRLKSKYKSRGSGILRYSPAGKISLKELVELMITKSDNTATNILTEIL-SF +DYLNGYFQQMGLRNTNFSRNIMDITKY-YRGIENYTTASDIAQILDKIYHYQLVSPEASE +RMLTLLKKQEI-RDRLPRYLPGYVEVAHKTGLFDN-VCHDAGIIFHPRGD-FLISILVSD +HQE-HRLAKELIGQVAKIAFEYy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Apibacter muscae TaxID=2509004 RepID=UPI0011AD302C +-----DSIQNVIKDKQATVGVGVIY-HNNDTL-SINNQYLYPTMSVYKFHQALAILNYLE +KNKLSLNTSYFIKKEDLDPYSPLFKERPEGNISIKDLLYYSLCLSDNNVSNYLFNYLVSP +VQTEDYIKSLGTDEISIKGTEKEMSQNHDNQYLNWTRPLATAILFNKILNKKIFKDEYQD +FLIETLIKTNTGENKIKGLLPKDLIVGHKTGNSYRDADNDAGFVLLPNGKKYTLAIFIMN +SKETDEVNASMIAKISRLIYNYy +>[subseq from] serine hydrolase n=1 Tax=Acidaminococcus provencensis TaxID=2058289 RepID=UPI000CFA3D94 +--KWQASLEALCQNSSGQVTLSFYDEKLRHGF-SVGGSCAVLSASTIKLLVLAEVFRQAE +EGSLSLAEGVTLTAEKRTGGDGILKELLSGHFTLKELCTLMIIVSDNEAANLLLDRV-GM +DKVNQLGEDLGLTATHLGRKMMDSAA-RDAGRDNWTCADDLVLLLRGIYEGTLVSPHASK +TMLEMLKRQQQ-GDRLQRYLPEDVPLAHKCGDLK-GVENDCGIFLLPDH-PYILAVLTQQ +QP-DSLTGKRTLGTLGKLVYDH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520IM74_SPHSX +-------------------------VDDGWTV-EAGGRQQLPQQSVSKLWVAMTVMDLRD +QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP +SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK +ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYGIAVMIGD +TIRPMPERQKLIQAAAAAVANY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A520X479_9SPHN +--RLDNALYEIGSLFDGYLGIAIVDVERGRTV-HFGGNQLFPQQSVSKLWVTLAALEQVD +AGKLSLDEPVLVGYSDLTLHQPIRNIVLARGGDFGDLMRRAITASDNTANDRLLRRIGGP +EAVRKTIVRNRLGAIRFGPGERAMQSSYVAKPVDGATPIAIAGALARLARGELLEPATTR +IFLDLLRDVKSGPNRLKGGVPPGWTIGHKTGTGQQAGFNDVGLLTAPDGARYAVAVMIGR +TAVPVPERMDMMHRVVAAVARY- +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Nostoc sp. NIES-2111 TaxID=1973475 RepID=A0A1Z4IDW1_9NOSO +--QLDAQIKQLMNRYSLSPGMFFLDMETGEYL-DINGEKTFAAASTIKFPILIALFQEID +AGRVRPNETLVMRRDLMTGGSGNMQYRKAGTFSLMETASKMMIISDNTATNMIIDRLGGK +NRLNQKFRSWGLQNTIIRNLLGDFKGT------NKTSPKDLVRLAAMISNNKLLSLNSNA +QVMDIMSRCHN-RSLLPVGLGKGAVIAHKTGTLGR-VLADAGIIQTASGKRYLAGIMVAR +PFGD-ARAKAFINQVSRLVYG-- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus borstelensis TaxID=45462 RepID=UPI00046863FA +--SLENALSTLLEKSGGQWGIYLEDLQTNEIW-GKGHDDRFYAASVIKVPIMAAVFAEAY +AGKFALEDKLTLRQEDQVGGAGILQHMTPGTWSIYDLTTLMIIQSDNTATNMLIDLV-GA +EAIRSVMNKTGMVNSQFHNKLMIVPAELEG--YNEVTAADLGSHLRHLATGKIISYNSCL +HMINIMKRQQH-RDRIPYHLPPKWELAHKTGTVTR-TTHDIGVMYIGNRA-VTICLLSKN +IE--TVAANDVMAQIGRMVYDLy +>[subseq from] serine hydrolase n=1 Tax=Sediminibacterium roseum TaxID=1978412 RepID=UPI00137B4186 +--ELLNNIKATLAQEKGTFAMTFIDLQTKQML-VINEHENFHAASTMKTPVMIEVFKQVA +AGKLSLQQMVTVKNESIVDSSTYSYTKVGRQVPLSELVYQMIILSSNLATNLVIELV-DG +KNVTQTMRTLGANDMQVLRGVEDTK-AFQKGLNNTTTAYDLAIVFSKMAEGKIVSPQACD +EMIKILLDQQH-NTVIPALLPKEVKVAHKTGSIT-GVHHDSGIVFLPNGKKYVLVLLSKN +IE-SDKAATGAMARVSKMIYD-- +>[subseq from] Serine hydrolase n=3 Tax=Bacteroidales TaxID=171549 RepID=A0A2L2WT04_9BACT +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRITIRELIEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQLYS +EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD +SNYDIATTSAIIAEVSKIVLE-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf28 TaxID=1735695 RepID=UPI0009E7D948 +-----NAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD +RGQMSLADPVTVTRSDLTVHQPIRALVGPDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP +VAINRMLAAKGIAGVTFGPGERHLQARYLAAPIDGASSNGVTLGLSLLAQGKLLSARSTT +SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAIAVMIAS +TRKPIPARMRLMGDLTRAVVA-- +>[subseq from] serine hydrolase n=1 Tax=Rubrobacter sp. SCSIO 52915 TaxID=2653852 RepID=UPI0014085AE7 +----RRAVEGYEKDHAGIAGAYVVDPGGGLGY-GVRADEPFFGASVMKVPVMVAVYRRID +EGELALSDMFETEEGDWAAGAGWLQWEEPGEHTVEDYLYMMMTQSDNVATNALIRKVGGL +EYVNEVAKDLGAKNTVLRQKVTS-ERAIVTGLDNQTTPRDMATMLAEVATGDAASEISCE +DMLDLMYQNVT-DRWLEAGLPDDVYAANKTGWLYK-VYDDAGVVQEGE-HPYVVAIFSKH +GPDDVEAGKELIKDVSESAWK-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. Marseille-P4200 TaxID=2040295 RepID=UPI000F63498B +--KLEDKIKNIIDNSGGDISVVFKNLKNNYCI-NINENKVFPSASTIKLVIMATFLKKVR +DGLVKLEDNIVLLNSHKCGGDGILKELNEGHFTYKEIITFMIIISDNTATNILIDFL-GM +DEINSMAESLNLKHTRIKRKMMDSE-AVKQGMDNFTTAKDLASFLTLLYNKEIINENYSY +IMLEILKRQQV-KGRLDLYLPEDLCIAHKTGDLDR-LEHDVGIVYTKNIN-YIICVLTSN +ID--NKNGREFIGRISKQIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Solibacillus silvestris TaxID=76853 RepID=A0A1A7M1U0_9BACL +----HKQLDRIIAQCPYKVHVIVEDYKTNEIVwENRAEEIFSSASIIKVPILIAILAHLQ +KTNGSLNQVFKIAPENMVDFSVITEQK-QIRATLHELLLWMTITSDNTATNVCIDLL-GM +DAFNDYFNEIGLHNTRVQRKMMDFERQ-KLGFDNVTTAQDMQQLFRKIYRGTLLTSEWNA +VALDILSRQRS-HESLKRYIADDVKMAHKTGGLDT-VDHDTGIVFLEVRD-YFIGVFITE +VT-DNDKARQTIGAISKIVYEHf +>[subseq from] serine hydrolase n=1 Tax=Paucisalibacillus globulus TaxID=351095 RepID=UPI000BB80B01 +-kELTERITQITEDAGGTWGISLQDSGTGESW-ELNGHELFYSASVIKIPIMIAVFAANH +RNEISLSNRLTVKREDMVGGSGVLQHMTPGILSITDLMTLMIIQSDNTATNMLIDLV-GT +EAIQQTMKDIGLVKSKFFHKMMTQEVD--RKGFNEITAHEMTDMLKKIATGKIISVYACE +QMIDILKKQQI-SNSLPAKIPEQWEIAHKTGNVS-GIRHDVGVFYVGKR-TLIASVLTKG +LN--NLESPEIIGRIGLEIYQY- +>[subseq from] Beta-lactamase n=1 Tax=Pedosphaera parvula (strain Ellin514) TaxID=320771 RepID=B9XGI6_PEDPL +--KTETQLQEIISHTRGAMGISVLDLTSNDRF-DINAEMVFPQASAIKIPVLMEVYKQAH +AGKFSLTDTRRIEKQDKTSGSGILFELGDGTMTIHDLCILMILISDNTATNLLIDLV-GI +TNVNQTLNSLGFEQTRLQRRMMDAAASLRGD-ENLSTPAEGVRILELLHKGEFINRSICD +DILAILKKPKP--TNLTAGLPDGTVVATKPGNIS-GVATEWAIVYLKDR-PYIVVIMENY +GVEH--DAPDAMKAISQTLHEYf +>[subseq from] Uncharacterized protein n=1 Tax=Rhodothermaceae bacterium RA TaxID=1779382 RepID=A0A1V0DF68_9BACT +--DLHARLEPLFARYEATVAVAVRDPHTNTRY-DFHAERLFHAASTMKVPVMIEVYRQAE +AGRFSLDDSLLVRNTSIVDGSTYRYRMLGRRMAIRDLVHRMITVSSNLATNLLIDLV-TA +DSVQATAERLGVRHMQVRRGVEDLLA-FRQGLNNTATAADLAVLFDALRRGAAVSPEADR +AMIDVLLDQQF-GDLIPAGLPPGVRVAHKTGAITR-IHHDAAIVYPERGPAYVLVVLTEG +ID-DRARSAELVAEVARAVHQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. CAG:598 TaxID=1262743 RepID=R5C210_9BACE +-tQLRTELQTYTDTLDAQIGIALL-LENGDSL-TLNNRQHYEMMSVFKFHQALAVCNYLY +HHNQSLDTLLHITPDDLKPWSPLRDRYLQEKISVRNLLEYTLQQSDNNACDILFDRLVSP +TETDRFIRSQGLTDFGIAYTEADMQKDHHLSKGNWSTPYAAASLLKHFLETDLIKEPYKA +FIKETMTSCQTGMKRLPAPLHTKAIIGHKTGSGYIGATNDLGFITLSDGTRYILAVFVKD +SGYNATQTEEIIGQISQIVFNH- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A3C1X2M3_9PLAN +-qTLEDRIRPLVQAHRGNAAVAVRHLDSGEQF-LWRAEIVQPTASLIKLPLMVTAYRQID +AGQLDAARMLTLAEADKVPGSGILTGHFSAGLSVRDAIRLMIRYSDNTATNLVAREV-GL +PATAACMQELGYSETRLNSFVYRGDTTIAPERSGSTTALETVGLLEQIQRGTVASADSCR +AMLQHLESCED-SAMLAARLPKGTKIAHKSGAVA-ASRTDAGLIYGPTG-VFAICVLTTE +NEEDSNAAHDLIATVARAAWDHf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus panacihumi TaxID=497735 RepID=A0A3M8DFH9_9BACL +--SLSPSIAKVLEEAGGQWGVYVEDLQTGEQL-AFNQDERFYAASVIKVPIMTAVFSEVY +AGKFALDTKIALRSEDQVGGAGILQHMTPGSWTVQDLVTLMIIQSDNTATNILIDLV-GR +DAIRAAMQATEMTNSRFYNKLMIVPAQVEG--YNEVTAADLGNHLRYLATGKVISYDSCE +RMIAILKQQQH-RDRIPHHFPPSWEFANKTGSVTK-ITHDMGILYIGSRA-VTICVLNKG +LE--QRPAVQAIAKIGKLVFDLy +>[subseq from] AMIN domain-containing protein n=1 Tax=Scytonema sp. UIC 10036 TaxID=2304196 RepID=UPI0012DAC637 +------QVKKLMSRYSLSPGMFFLDLETGNYL-DIYGEKVFPAASTIKYPILIALFQDID +AGKIKLNETLVLRRGLKAEGSGVLQKPVGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLARLSVMIDNDKMLSNTSRA +KVLGIMRRVQN-RRLLPSGLGKGATIAHKTGTLGI-ILGDAGIVELPTGKRYLAGIFVKR +PFGD-TRAREFISQVSKLVYG-- +>[subseq from] Class A beta-lactamase n=1 Tax=Fusobacterium sp. CM1 TaxID=936561 RepID=X8HRV2_9FUSO +-tEWKKEIEKIISQVEGSVCINFYDLAKNTGF-SIDGDKKVLSASMIKLLILAELVKKVS +ENKFSLSDAITVTEAMKTGGDGVLKELNSEHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINQLGRELDLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQEKLINKKASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIEDKA-YILVVLTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus beijingensis TaxID=1126833 RepID=A0A0D5NJ11_9BACL +--ELRSNIEQLTGQAGGMWGVTVTDLHSGEKM-TLNGSEPFNSASIIKVPIMAAAFAAVY +DGELALGSRIECRLDDMAGGSGIMRHLTPGVLTVNDLITLMIIQSDNTATNMLIDAL-GT +NRIQATVAELGMTNTRFYHKVGLMMAQPE--GRNTITADDAAIMLTRLGEGSFISRHACQ +QMIDIMKNQQY-RNGLPQQLPAAWELANKTGWVD-GIQHDAGILYAKGRA-VAVTVLSRN +GG-TPSEALACIAAIGREVYRY- +>[subseq from] serine hydrolase n=1 Tax=Runella limosa TaxID=370978 RepID=UPI000404EC73 +--SLKETIQARLKTVEGEFGVAFKDLQTQETL-FINGHENFHAASTMKTPVMIEVFKQAK +AKKFNLTDSILVKNESIVDGSPFKYRQIGKKMTIYDLTYQMIIVSSNLATNILIDLV-DA +KNANATMRQLGAQDIQVLRGVEDTK-AFQKGLNNSVTAYDLMLIFEKIALKKAVNKKACD +AMIRILLDQKF-NEIIPAQLPTNVNVAHKTGSIT-GVQHDSGIVFLPDGRKYVLVLLSKK +LTN-PKEGVKALADISRLIYD-- +>[subseq from] Beta-lactamase n=1 Tax=Nostoc commune NIES-4072 TaxID=2005467 RepID=A0A2R5FYC4_NOSCO +--ELKTPIKALMARYRLTPGIFFMDLQTGDYF-NFNGDKAFSAASTIKYPILIALFQEVD +AGRIKLGETLVMRRKHVTGGSGDMQQRVGTKLSLLQTATKMMTISDNTATNMIIDRLGGV +SKLNQKFRSWGLQSTVIRNMLGDFKGT------NKTSAKDLVRLSALVTNNHLISDISQS +QVLGIMIHCHN-RALLPSGLGSGANIAHKTGTLRF-VLGDAGIIETPSGKRYLAGIFVRR +PNND-IRARDFIRQVSRVMYGYf +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacteraceae bacterium TaxID=2026738 RepID=A0A2E5DND4_9SPHN +---LESRIAQLADGSNGRIGVYAVDLTSGREI-GVLADQRFPLASTSKVAIAATYLAGVD +EGRWSLTSEYRLPR-------------PGGAMPAYRHLSLMISKXCNDCTDALLNAVGGP +SAVNKWMRGAGIEGFELTRNIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSEHSRR +VLLDAMLETTTGKRRMRSVLPVSANLAHKTGTLAR-TASDIGIFLTPDGRAIAAAIYVTG +QSPSMA----------------- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium CG11_big_fil_rev_8_21_14_0_20_64_6 TaxID=2014311 RepID=A0A2H0PC50_9BACT +--EMTGRLAKMAVKYPGRVSIYLKDLKTGRTW-MHHPDDLFPAASLIKVPVMIAAFYKIR +DGHLDLDERIAITRRNRVGGSGSLKWRPDGTLSVRELLVHMINESDNTATRMVLDRI-GI +GYVQQQFPRMGLLYTGIYEEGMSIKGG-RVMHENYTTAREMSMLMDKIYSGKAVDKVSSE +VMLGILKKPKAVASRLAKGMPRGWEIAHKTGLLRQ-ACHDSAIFMTPNGD-YALTVLTGQ +NR-SYSTAKDFITKAGKVTFNHy +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000858A0EE +------------------------------------------------------------ +------------------PYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sp. JS21-1 TaxID=1855283 RepID=A0A1H7RM44_9SPHN +------------------------------------------------------------ +----------------------------------SRVMELMIVRSDNQAADQLLAAVGGP +VVVQQWLNAHGFSGIRVDRTIAQLLRGHLADVKDVATPTAMVAFLSRLEDATVLTARSGA +YLFDLMRRCATGTRRIRALLPPGTTVEDKTGTLD-GVTNDVGFITMPDGHRVAIAIFARG +GR----DRQPGIAAVARLVYDRf +>[subseq from] class A beta-lactamase n=1 Tax=Bacteroides togonis TaxID=1917883 RepID=UPI00094AF462 +-tQLRTELQTYTDTLDAQIGIALL-LENGDSL-TLNNRQHYEMMSVFKFHQALAVCNYLH +HHNQSLDTLLHITPADLKPWSPLRDRYQQEEISVRNLLEYTLQQSDNNACDILFYRLVSP +AETDLFIRNLGLTDFGIAYTEAEMQKDHHLSKGNWSTPYAAASLLKHFLETDLIKEPYKA +FIKETMTSCQTGMKRLPAPLHAGAIIGHKTGSGYIGATNDLGFITLSDGTRYILAVFVKD +SGYNATQTEEIIGQISQIVFNH- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Nostoc TaxID=2593658 RepID=A0A235I2L4_9NOSO +--ELKTPIKALMARYRLTPGIFFMDLQTGDYF-SFNGDKAFSAASTIKYPILIALFQEVD +AGRIKLGETLIMRRKHVAGGSGDMQQRVGTKLSLLQTATKMMTISDNTATNMIIDRLGGA +SKLNQKFRTWGLQSTVIHNMLGDFKGT------NKTSAKDLVRLSALVTNNQLISGTSQS +QVLGIMIRCHN-KSLLPSGLGSGANIAHKTGTLRF-VLGDAGIIETPSGKRYLAGIFVRR +PNND-IRARDFIRQVSRVMYGYf +>[subseq from] AMIN domain-containing protein n=1 Tax=Aphanocapsa montana TaxID=327565 RepID=UPI00140E1ECB +---LTQRLAALHSQYAVDPSVFVLNLNNGDYA-DLQGGAPFPAASVIKLPILIAYLQDLD +AGKVSLDETLVMRPELVASGSGYMQDLPDWSFSARYTLTQMIETSDNTATNMIIHRLGGP +AYLNRRFQSWGLKDTQIRNWLPDLSGT------NTVSSHDLATVLTKVVKGNLLSSQGRQ +RALYILKLTQT-RSLLVPGIGRGASIAHKTGDIGF-ALGDAGIVFMPGGQDYVISVLLRR +PYND-PRGRDYVQRVSKTVYAYf +>[subseq from] serine hydrolase n=1 Tax=Larkinella sp. C7 TaxID=2576607 RepID=UPI00111143CA +--------------AQAQVNVAFESLTDDTRF-FHRPDELVPSASVIKIPIMIETMEQVK +AGKFDLEKVHVLLASEKTGGSGVLQTYPDESLTNLEVLTLMMIRSDNSATNILIREL-GM +DNINRRMQTLGLTQSRLNRVMMDTLAA-KQGRENRVTAREMNLLLKKIYRNEVATPALCA +QMIDILKRNAD-QTTFRLFLPKSAVIAHKTGELTY-VRGDAGIFYVT--RPFLLSVFVQG +TT--TPEAEKIIGEIAAICYNQy +>[subseq from] Serine hydrolase n=1 Tax=Larkinella knui TaxID=2025310 RepID=A0A3P1CX28_9BACT +--QLRRQIEAELAKQPGRFAVAFKDLSTGEQL-FIREREEFHAASTMKTPVMIEVFKQAA +QHRLSLSDSVLVKNESIVDGSPFSYKKVGTKRTLYGLMYDMIILSSNLATNLIIDLV-EA +RNVTQTMRDLGAKDIQIRRGVEDTK-AFQKGLNNTTTAYDLLVIFEKIATGKAVSPEASE +AMIKVLLDQHF-SSVIPAKLPKEVKVAHKSGSFAT-VRHDSGIVYLPDGHKYVLVLLSKE +MK-DDAAATETLASVSGLIYQY- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas aurantiaca TaxID=185949 RepID=UPI000D3802D8 +-----NAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD +RGQMSLADPVTVTRSDLTVHQPIRALVGPDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP +VAINRMLAAKGIAGVTFGPGERHLQARYLAAPIDGASSNGITLGLSLLAQGKLLSARSTT +SLLTLMHSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAIAVMIAS +TRKPIPARMRLMGDLTRAVVA-- +>[subseq from] ClassA n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SLC1_9BACT +--SLTYQIKEIIAGKNAQVGVAIIHGDETWTI----GQGKQSLMSVFKLFIAMQVLDKLE +KDKTDINQMVTITEDMVDRYTPMLKVYPQTPIPMIKLIEFMVSESDNNAANFLMEYTGGA +EGLENYLKQLGFPEIEIKVSEAKMTADVKSQLLNKAYPMDVIRLLKQVREGNFLSDKNKK +LLDEMLIKTMTGENKIKKYLPSEVVIGHKTGSSDTGADNDVGFVRLADGCEYYLAVMVTD +SSLSDEDNAELIAKVSKVVYDNf +>[subseq from] serine hydrolase n=1 Tax=Ornithinibacillus contaminans TaxID=694055 RepID=UPI00064DF7F0 +-kQLTKRIQEIIKHAGGTWGISLEDLTTNEAW-GLNTEESFYAASVIKVPIMIAVFDAHH +QGALNLTDTVHLDRDALVGGSGVLQHLTGTRFTIHDLLTLMIIQSDNTATNILIDLL-GV +EKIQQTMEKQGLVKSKFYHKMMTVPVD--REGINEITAREMTVMLKKLVTGKIISAYACE +QMITIMKKQQI-RTTLPGKIPTNWEIANKTGSVS-GIRHDIGIFYVGKR-TLVAAVLSKD +VD--DIRAVDALGEIGLEIWQ-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=D1LFJ3_9BACT +------------------------------------------------------------ +-----LNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRADLPTSWT----------------------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Omnitrophica WOR_2 bacterium SM23_72 TaxID=1703777 RepID=A0A0S8IJE0_9BACT +-nRLNQEIGQEIGQFKGEAGIVIRDLDKDWEL-FYKKETLFPSASLAKIPLMAGSFLAAQ +EGRLKLERNVKLKSTDKFSGSGVLKDHPGVEFSVEELIGLMIYDSDNTATNMVTGMV-GT +DYLNNFFKNIGLKNTNLSRRIADYSLR-KRGIENYTTAEDMARILEKIYRKTLINKEISE +RCLKLLKLQRL-NDRIPKYLPAELTIAHKTGLER-GVCHDAGIVYTPKGD-FLICVLTKH +KNANSIPSKEFIARISLYVYRYf +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=A0A2S0K6S7_LYSSH +----QPTIQRIIQEAPYKVHMFVKDFKTNDFViNERLDEAFSSASLIKVPILIAVFDYID +VCDIPINQVIAISPSDWVDFSVISEQRVT-SCTIYELCVWMITTSDNTATNVLIDVI-GM +EALNKYFHKIGLTHTQLQRKMMDFER-LAKGIDNITTARDMAHLFSQIYRQNLLSPVLSQ +LAIDILCRQRF-HECLRRYIVDDVTIAHKTGGLDT-VDHDVGIVYSHVQD-YGIGVFISE +VKQN-DVARQLIGRLSKVVYDK- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=D1LFH9_9BACT +------------------------------------------------------------ +-----LNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDATTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWT----------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus formosus TaxID=54913 RepID=A0A4Y4I2D2_9BACL +---LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY +AGKFALEDRIKLRAEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT +ESIRNAMQKTEMTNSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL +KMIAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG +LE--QKDAANVMAQIGNLVYHVy +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9BBA2_9BACT +---AESAIVTRIAKSGADVGVYFKTLDGKSVW-SSRAEDVFHAASTMKIPVMIELFHQVN +QGKLKLDDPLTIKNESIVDGSIYTYKAEGQTRTVRQLCELMITVSSNFATNLLIEKL-GV +ENIRATVHALGADGVNVLRGVEDD-KAYEKGLNNTTTARGLAILLQAIAEGKAVDAESCK +EMIAVLERQKF-NEGIPAGLPQGTPVAHKTGEITK-IHHDAAIVFAK--RPFILVILVRG +LV-DIKESSALMADVSKSLYE-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Bathyarchaeota archaeon RBG_13_52_12 TaxID=1797379 RepID=A0A1F5DSE9_9ARCH +--------------FEKVIGVAVKHLGTGEEA-SFNGDVLFPTASVFKVPVIVELYRQVE +AGKLSLDDKMVLKEAEKVPGSGILKELSEGLVTIKDLSRLMMILSDNTATDLLVERV-GK +DNVNAAMQRLGLNKTTVVADCRDLLFSLGTEKNDVTTPLEMNKLLGLIVEGKAAGRVGCE +AILATMEKCQTGEYRVPKYLPESVKMNRKTGSLP-GIRNDVGVITIKTGEKYCISCFTKG +AP-DVYAAEETIARISRNVYQYf +>[subseq from] serine hydrolase n=1 Tax=Asinibacterium sp. OR43 TaxID=1076522 RepID=UPI00047951DF +-eQLMQQVKDTLALQKGFFAVAFRDLSTGETL-LWNEHESFHAASTMKTPVMIEVFKQAE +AGRFSLNDSIPVKNTSIVDGSPYKYHQTGTKMLLKELLRQMIIRSSNLATNILMEMVSG- +TEVTKTMRSMGAKDIQVLRGVEDQK-AFDKGLNNTTTAYDLMLIYEQLSLGKAVSVAASK +SMIDVLLDQQD-NSVIPAGLPPVVKVAHKTGSIT-GVHHDSGIVYMPDGRQYVLVLLSKQ +LA-DDAAATKAMSRVSGLFYDY- +>[subseq from] Serine hydrolase n=1 Tax=bacterium TaxID=1869227 RepID=A0A522L995_9BACT +--KLKKDIGNKVGHFRGTVGMVIEDLDMGWKI-TFNEDTLIPSASLVKVPIMLSCFYAAQ +DGKISLKDAISLKSSEKVSGSKVLGKEPPGAFTVEELFNPMITQSDNAAANVLIDFL-GL +DTLNRYFKKMGLKNTNIARRMMDFVER-RAGEENYTTAQDMAYLLEELYYRKFLNKEVSE +KCLKLLGEQKI-NDRIPRKLPRGTYVVHKTGLEKH-VCHDVGVVFTNKGN-FLICVLAKH +EDRLAKHAKRFISDVTLLTYNYy +>[subseq from] serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=UPI0001B8F083 +-tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGDKKVLSASMIKLLILAELMKKVS +ENKFSLSDAITVTEAMKTGGDGVLKELNSDHFTLKELATLMIIVSDNQATNILIDFL-GM +KNINQLGRELDLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILAVLTNG +MP--NFQCKQTIGKISKFVYDK- +>[subseq from] Beta-lactamase class A n=2 Tax=Chitinophaga japonensis TaxID=104662 RepID=A0A562TDF4_CHIJA +--TIKQRILDTLAGHPGIYAVAFRNLVTGEEI-LIREKETFHAASTMKVPVMIAVFKQAA +AGRFSLSDPIMVKNTSIVDSSEYEYRQVGTRRTLSDLVYRMIIKSSNLATNMVIELV-GG +QYVTQTMRELGAQDIQVLRGVEDGK-AYRAGLNNTTTAYDLLLIFEKMAQGETVSPAASE +DMIRILLDQRF-NSIIPAQLPAGVKVAHKTGEIT-GVRHDAGIVFLPDGRKYVLVLLSRE +LEN-PEEGAQAMATVSRMLYDH- +>[subseq from] Uncharacterized protein n=2 Tax=marine sediment metagenome TaxID=412755 RepID=X1IFD0_9ZZZZ +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPG------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8QBV1_9BACT +----------------------------------------------------MAVLKRID +NNTLTFDDKITVRPRDFVSEFSIATKYPKGALPVRELLDYMISESDGTACDVLMRMLGGP +EAVTINLREWGVNDIKLVTYESDMFKTPSVSFLNWSSPEAMVQLLKLLQTEKVLSAERRD +ILLSLMIKSRPGQQRIKGLLPPGTMVAHKTGTSDTTATNDVGIITLPNGQHLAIAVFVST +TKADEKTREDVIAKFARAASDCw +>[subseq from] Serine hydrolase n=1 Tax=Spirosoma sp. KCTC 42546 TaxID=2520506 RepID=A0A514ZUY2_9BACT +--ELRQKIETELSRQTGIFAVAFKDLATGKEL-LIRERDVFHAASTMKTPVMIEVYKQQA +QGKLSLSDSILIKTESIVDGSPYTYKQIGTKRTLASLVYDMITVSSNLATNLIIERVGGP +-NVTQTMRDLGAKDIQVRRGVEDSK-AFAKGLNNSTTAYDLMLIFDKIATGQAVSPEASK +AMIATLLEQKF-NDAIPAKLPKTVKVAHKTGSIV-GVRHDSGLVILPDGRQYVLVLLSKD +IK-DDKATSGAMATVSEWIYQY- +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides TaxID=816 RepID=A0A174J2U0_BACVU +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRITIRELLEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGALEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQLYS +EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSVAVFVAD +SNYDIATTSAIIAEVSKIVLE-- +>[subseq from] DUF3471 domain-containing protein n=1 Tax=Sphingobacterium alkalisoli TaxID=1874115 RepID=A0A4V5LYX8_9SPHI +--DLKSRIQKIMAKQEGRFAYAFMDLQTGEQL-LFNAQEMFHAASTMKTPVMVEAFKQAA +EGKFSLSDSITVYNNSIVDKSKFSYARLGKKMTRHDLIFRMITASSNLATNIIIDQV-GA +KNVMKTMKSIGADDIRVLRGVEDSK-AFQKGLNNQVTAYDLMLIFERIAKGNLINKTASE +GMIKILKAQKF-NSIIPAQLPDDVEVAHKTGSIE-GICHDSGIVYLPGGRSYVLVLLSGK +LK--DADARKTLADVSRQFYNYf +>[subseq from] serine hydrolase n=1 Tax=Asinibacterium sp. OR53 TaxID=925409 RepID=UPI0004794A83 +-eQLMQQVKDTLALQKGFFAVAFRDLSTGETL-LWNEHASFHAASTMKTPVMIELFKQAE +AGRFSLNDSIPVKNESIVDGSPYKYHQTGTKMLLKELLRQMIIRSSNLATNILMEMVSG- +TEVTKTMRSMGAKDIQVLRGVEDQK-AFDKGLNNTTTAYDLMLIYEQLSLGKAVSVAASK +SMIDVLLDQQD-NSVIPAGLPPGVKVAHKTGSIT-GVHHDSGIVYMPDGRQYVLVLLSKQ +LA-DDAAATKAMSRVSGLFYHY- +>[subseq from] class A beta-lactamase n=1 Tax=Bacteroides paurosaccharolyticus TaxID=732242 RepID=UPI00046A56BD +--TLEEMINRKIREVKADVGVAII-INSKDTL-AINNEHNYPMLSTYKVHQAMKVVDFLR +EKSVPLTNEIEIPASQLKSYSPLQQKYPSGVLPVSEILRYSLQLSDNNACDILFSLVGGP +MVVNRYLESIGVHDCNVAYTEDEMRQDINRAYDNWTTPLEGAIVMEKLFCGEIGDDQYSS +FIKEILYNSKTGEKRIPCLLPKDIKIAHKTGTGPKKGVNDIGFIELPNGKHYSIAIFIKD +SYEDMQRNELLIAEISEIVFN-- +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium 13_2_20CM_2_54_15_9cls TaxID=1805418 RepID=A0A1Q6WW96_9BACT +-kKLETRVEEIAARLDGVMGVAVLDLTDGRVL-LRNADRVFAAASSIKLAILLELYRQDQ +KGKARLDDIYSFDPKDLVEDSRIMAGLTPGVVTNRDLAQFMVAVSDNAAANVLIDRV-GR +DNVNAMLRSLGLSKTVLRRKMMDIAAARRG-DENVATPQEMVRLLEAIFKEKAVDKESTA +GLIKQLSTKK--DSYIPRLLPDDVQVANKPGELE-GVRNDSGIVFAAHR-PFGISVMTAY +DR-DEKAAERAISDVALEAYQYf +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00098F7BE0 +------------------------------------------------------------ +----------------MVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] serine hydrolase n=1 Tax=Rufibacter ruber TaxID=1783499 RepID=UPI00082B137F +---VKAAILAELGKQEGTFAVAFKDLETGEEL-LIQEHERFHAASTMKTPVLIEAYRQAA +QGRFSLQDSLLVKNESIVDGSPFSYSLLGQKRPWSELLYKMIIHSSNLATNLVIEQL-DA +QKVTQTMRQMGAQDIQVLRGVEDTK-AYQQGLNNTTTAYDLLLLFQQIAQGKAVSPAASQ +EMIQILLDQKY-KDIIPAKLPREVQVAHKTGWIT-GVRHDAGIVFPPNGHPYVLVLLSKG +LS-DEQAGIKAMATVSEMLYG-- +>[subseq from] All4822 protein n=2 Tax=Nostocaceae TaxID=1162 RepID=Q8YMV4_NOSS1 +--QLDSQIKRLMNRYSLSAGMFFLDMETGEYL-DINGEKTFAAASTIKFPILIALFEEID +AGRINPNETLVMRRDLMTGGSGTMQYRKAGSFKLMETASKMMIISDNTATNMIIDRLGGK +NRLNQKFRTWGLQNTVIRNLLGDFKGT------NKTSPKDLVRLAALISNNKLLSATSNS +RVMDIMSRCKN-RSLLPVGLGKGAVIAHKTGTLGR-VLGDAGIIQTPSGKRYLAGIIVAR +PFGD-ARARAFINQVSRLVYG-- +>[subseq from] Beta-lactamase n=1 Tax=Brevundimonas abyssalis TAR-001 TaxID=1391729 RepID=U3ANB0_9CAUL +-----------------------------------------------------------A +RGEERLDRALPITSDDMISHAPVTGPAVGGALTIEALCRSTVELSDNPAANILIREMGGL +DSWRNWYRSIGDSVTRVDRLEPELNLV--GDERDTTTPTQAVANMARLLAQTRLTAAHQT +LLERWLTDSPTGPNRIKAAAPDGWRVGHKTGTSSLGPVNDIGVIWPPEGAPIFVAAYYEG +PPDDFAAGEAVIAEAVGRALEA- +>[subseq from] Beta-lactamase class A n=1 Tax=Pontibacter mucosus TaxID=1649266 RepID=A0A2T5Y1U0_9BACT +-dDLRQQINATLGAQQGTFAVAFKDMQTGKEL-LLNAQESFHAASTMKTPVLIEAYRQAS +EGRFSLSDSILIRNESIVDGSLYSYTLVGQKRPVSELLYKMIIQSSNLATNLVIAEL-DA +KQVTQTMRELGARDIQVLRGVEDSK-AYERGLNNTTTAYDLLLLFEQIAAGKAVSPEASQ +DMIRILLDQRH-REIIPARLPEGVKVAHKTGWIT-GVRHDSGIVILPDGRKYVLVLLSKD +LK-DEKAAMEAMATVSEMIYKY- +>[subseq from] Beta-lactamase class A n=2 Tax=Hydrobacter penzbergensis TaxID=1235997 RepID=A0A1H2T4R0_9BACT +-eQLMQQVKDTLALQKGFFAVAFRDLSTGETL-LWNEHESFHAASTMKTPVMIEVFKQAE +AGRFSLNDSIPVKNASIVDGSPYKYHQTGTKMLLKELVRQMIIRSSNLATNILMEMV-SG +AEVTKTMRSMGAKDIQVLRGVEDQK-AFDKGLNNTTTAYDLMLIYEQLSLGKAVSVAASK +SMIDVLLDQQD-SSVIPAGLPPGIKVAHKTGSIT-GVHHDSGIVYMPDGKQYVLVLLSKQ +LADD-AAATKAMSVVSGLFYH-- +>[subseq from] Serine hydrolase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520DV48_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +RRVEAVRRAMGVKAGDLQRTIDEAYARYYKHQRNSATLEAYGTLLEQLVRGKLLSPASTQ +RLFTAMKFGPPGGYRLAGGLRQDVKFIHKTGTQYR-TACHVGVVNPQDGAKAIVVASCAR +DLDDQREAGKVFTEVGRAV---- +>[subseq from] Serine hydrolase n=1 Tax=Rufibacter glacialis TaxID=1259555 RepID=A0A5M8Q5M8_9BACT +-----EEVLAELGKQEGTFAVAFKDLKTGEEL-LLNEHESFHAASTMKTPVLIEAYKQAA +EGKFDLTDSILVKNESIVDGSPFTYTQLGQKRPLSELLYKMIIQSSNLATNIVIEKL-DA +KNVTQTMRALGAKDMQVLRGVEDTK-AYRQGLNNTTTAYDLMVLFQKMAQGKVVSPAASQ +DMIKVLLDQKF-KEIIPAKLPQDVKVAHKTGWIT-GVRHDSGIVFLPNGRQYVLVLLSKG +IA-DDKASVAAMANVSEMIYRH- +>[subseq from] Class A beta-lactamase n=1 Tax=Muribaculum intestinale TaxID=1796646 RepID=A0A4S2FVF4_9BACT +-kAIEKALLEYVSDKDARIGIAVI-VNGTDTI-SVNGKRDFPMMSVVKFPLALTVVQWID +ANGLSLNDSIAFSQKALKEYSPMLKRYGKKRMTVRELLEWSLVESDNNASDILLNHVGGI +SGATKIMKKIAIDNIEIGASEDDMHRDPYLSYLNRTTPLAMAELFDRFDNEMRNTSLSYS +EIATMLEQCRTGIDRLVAFLSSDATIGHKTGTGFISAINDCGYVNLPNGARYSIAVFVAD +SGYDMAETSAIIAEISRIVW--- +>[subseq from] Beta-lactamase class A n=1 Tax=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) TaxID=886293 RepID=L0D6A5_SINAD +--ELERTIRTLVEG-AGDVAVAYCRLSDGEQV-FIKGDERFHPASTMKVPVMMEVFRQAE +EGTLALDGRIRLKNESIADGSRYSYRHLGDERTVRDLVRLMITESSNLATNLLIERV-TA +ARVSELMKSMGAGDVRVLRGVED-NRAFQRGLNNETTARGLATIFRQLAARRVVSAKASE +EMLAILRDQKF-NEGIPAGLPAGVPVAHKTGWIT-AISHDAAIVEPGGRSPYVLIVLTRG +IK-DPAKAHELIARVSRAVYEH- +>[subseq from] Uncharacterized protein n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0N7F1R6_9BACT +------------------------------------------MISAFKFHIALTVLDKVD +KGELSLTQKLFFKKSELLEWSPFREKYPNGDITLKEALQWTISVSDNNLCDILIRLVGGV +KTVDNFINS---ADFIIKNDEEGMHQNWDAQFLNTTTPNFSNQLLKRFLENKLLTKKSTK +FLYKTMVSTSVGQNRIKGKLPTNTEVAHRTGSSFTGAINDIGIVRLPNGKYFIISIFVHN +TTEKFKDGEEIIADITKATWDNy +>[subseq from] Serine hydrolase n=1 Tax=Duncaniella muris TaxID=2094150 RepID=A0A2V1IIK9_9BACT +-kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN +TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSLMTVRELLEWSLVESDNNAADILLHRVGGT +SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQLYS +EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSVAVFVAD +SNYDIATTSAIITEVSKIVLE-- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7EK04_9BACT +--------TRIAQEPGAYVGLAYVDLASGDTL-FLNADSSFHAASTMKVPVMIELFRRAN +TGSFGMNQGLLMVNQSLVDGSRYAYHRIGDRVSVDTLLRLMITRSSNFATNTLITLV-GA +EEVTRTMRALGAQRIQVLRGVEDGK-AFEKGLNNTTTARDLAIILRAIQEGKAASPPATR +EMLAILLAQEF-NEKIPAGLPPGTRVAHKTGEIT-AVSHDAAIVYPAGRKPYVLVVLTRG +IT-DGAKASKLIADLSSIIYQH- +>[subseq from] serine hydrolase n=1 Tax=Xenophilus sp. E41 TaxID=2282216 RepID=UPI000EF5BCCC +------------------------------------------------------------ +------------------------------------------------------------ +ARVRKVSQLLDVPVSRLRMPLEDAYTAYYASGVNSGRLDAYGQLLALLVDGRALGRPMTD +YLLQVMERTATGTRRIKAGLPPDARFAHKTGTQRR-RICDAGLVTSPRTAARVLVVACVR +GDLSLERSERALQQVGAALC--- +>[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. BC25 TaxID=1144308 RepID=J2FYK9_9BACL +---LFAQISSLIKDAGGEWGIFFEDLQTGETF-SFNEDQRFYAASVIKVPIMTAVFAEAY +AGKFALEDKIKLREEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT +ESIRNAMQKTEMTNSHFYNKLMVVPAELEG--YNEVTAKDMGRHLRYLATGKVISYDSCL +KMVAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILFIGSHA-VTLSILNKG +LE--QKDAADVMAQIGNLVYHVy +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5KYY8_9BACT +-kKLETRVEEIAARLDGVMGVAVLDLTDGRVL-LRNADRVFAAASSIKLAILLELYRQDQ +KGKARLDDIYSFDPKDLVEDSRIMAGLTPGVVTNRDLAQFMVAVSDNAAANVLIDRV-GR +DNVNAMLRSLGLSKTVLRRKMMDIAAARRG-DENVATPQEMVRLLEAIFKEKAVDKESTA +GLIKQLSTKK--DSYIPRLLPDDVQVANKPGELE-GVRNDSGIVFAAHR-PFGISVMTAY +DR-DEKAAERAISDVALEAYQYf +>[subseq from] serine hydrolase n=1 Tax=Spirosoma sp. I-24 TaxID=2666025 RepID=UPI00138E751A +-dQLRQQINQELAKQSGVFAVAFKDLSTGQEL-FIREHDVFHAASTMKTPVMIEVYKQVA +QKRLSLADSIPIKTESIVDGSSYSYKEVGTKRTLASLVYDMIILSSNLATNLVIEQA-DA +QKVTQTMRELGAKDIQVRRGVEDSK-AFEQGLNNTTTAYDLMVIFEKIATGQAVNPEASK +AMIDILLDQRF-MSKIPAKLPKEVKVAHKTGSIK-GVSHDSGIVFLPDGRQYVLVLLSKD +LKND-QAADNTLATVSELIY--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=D1LFJ5_9BACT +------------------------------------------------------------ +-----LNQRVEIKKSDLINYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIVHLGGP +DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGKALAETQRA +QLVTWLKGNTTGSASIQAGLPTSWV----------------------------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Vibrionimonas magnilacihabitans TaxID=669455 RepID=A0A2S8SIP8_9BACT +-eQLMQQVKDTLALQKGFFAVAFRDLSTGETL-LWNEHESFHAASTMKTPVMIEVFKQAE +AGRFSLNDSIPVKNASIVDGSPYKYHQTGTKMLLKELVRQMIIKSSNLATNILMEMV-SG +AEVTKTMRSMGAKDIQVLRGVEDQK-AFDKGLNNTTTAYDLMLIYEQLSLGKAVSVAASK +SMIDVLLDQQD-SSVIPAGLPPGIKVAHKTGSIT-GVHHDSGIVYMPDGKQYVLVLLSKQ +LADD-AAATKAMSVVSGLFYH-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chamaesiphon minutus (strain ATCC 27169 / PCC 6605) TaxID=1173020 RepID=K9UP01_CHAP6 +---LDRRLQATLNRSKIDPSYLFVDLNSGEYT-QLGADRVLPAASTIKLPILIALFQDVD +AQKVQLEEKLTIDKNSIAGGSGDLQQKPGTQVSILVAATKMMTISDNTATNLIINRLGGA +TKLNQRFRNWGLKVTTINRPLPDLEGK------NTTTPRELARTMMAIDPGKLLSDSSTS +QILSIMSNT-IGNTMLPKGLGAGAKIAHKTGDIGS-TIADVGAIELPSGKKYLAAVIAKR +PYND-PDGPALVRSMSKIVYEQf +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Calothrix sp. NIES-4101 TaxID=2005461 RepID=A0A1Z4RJM5_9CYAN +--QLAAQVRTLMARYSIEPGIFVLDLDTGNYL-DYNGEKVFSAASTIKFPILIALFQEID +AGRIKPNETLVMRRDLITGGSGNMQYKPAGTFNLMETATKMITISDNTATNMIIDRLGGK +SKLNPRFRNWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALISNNQLLTNSSQT +KVIDIMRRVQN-RSLLASGIGKGAVIAHKTGTLGV-ILGDAGIIQLPSGKRYLAGIMVRR +PFGD-SRGTQFISQVSKVVYG-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A0D9AMM6_PSEST +------------------------------------------------------------ +------------------------------------------------------------ +-RLELLARLLGVPKSELRARLREAYERYYATPNNSATLQAYGDLLAALVAGKAVSRASTE +YLLGVMTRVQTGDQRIKAGLPATVSYAHKTGTQV-ARICDAGLIAPPATGRIVVVACVRG +-AASTVKAERALRGAGEAIT--- +>[subseq from] serine hydrolase n=1 Tax=Dyadobacter sp. 3J3 TaxID=2606600 RepID=UPI00135AA69A +-eDLKQKISEELAKHKGSYAIAFKDLKTGEEF-GINEHETFHAASTMKMPVMIEVFKQAS +QGKFKLTDSITIKNESIVDGSLYSYRHIGEKRAIKDLVYEMIIVSSNFATNMVIDLV-GA +KNVTQTMRDLGAKDILILRGVEDAK-AFQKGLNNTTNAYDLRLLFEKMALGKIVNQKACD +AMIKILLDQKF-NDVIPGNLPKDVKVAHKTGGLPN-IQHDSGIVFLPDGRKYILVILSRD +WE-SEAANRKMLAGISEMIY--- +>[subseq from] serine hydrolase n=1 Tax=Caulobacter sp. UNC358MFTsu5.1 TaxID=1449049 RepID=UPI000AA08038 +-qKLTAQFQPIADRVPGQLGVGLEDLGTGQII-SFNGERRFPLQNVAKAPLGAAVMAEVE +GKRLRLDDVLLIEDVDLSPPSPLADAWTGPSHTVQELLERAIRDGDNTAADILMKRVGGP +GAVTAWLQGRKVMNLDIDRYERQLQPAYLADPRDTATPLGALRFLEALNQAELLNADSRR +LLGGITRQVTAGPDRLRAALPRDAQLVHVPGTARTDVVNDIGVYTLKDGRKFAVVVFISG +SPLPLAEQEKAIADVGRVVIK-- +>[subseq from] Uncharacterized protein n=1 Tax=Omnitrophica WOR_2 bacterium RBG_13_41_10 TaxID=1801849 RepID=A0A1G1MBI9_9BACT +----EAGINKEILSFNGKPGSTIKDLSNNWQI-KINPNGSFPAASLVKIPIMAACFYAVN +EGRLKLDENLQLRTKDKVLGSGNLKNLASGRFSIQQLLEIMITESDNTATNMLIERI-GF +DYLNDCFKKIGLKNTNISRKMMDFKSR-RHGRENFTTASDLAFILEEIYRNKLINRKYSQ +KCLGLLKKQNI-RDRIPSRLPQEICVAHKTGLER-GICHDVGIIFTHRT-NILICVLTKH +NNKTARLAKNFIARVAFLTYR-- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas insulae TaxID=424800 RepID=UPI0013CF630C +-----NAVQALGAGFAGDVGIAVRDIDEGWSV-AWAGDTPRPQQSVSKLWVAIAVMDAID +RGRMSLTDPVTVRRSDLTVHQPIRALVGPDGTTVGDLLRGAMTRSDNTCNDVLLWRVGGP +EAIRRMLAAKRIAGVTFGPGERELQARYLAAPIDGASANGVTLGLSLLAQGKLLSARSTA +SLLALMRSSRTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPNGHRYAVAVMIAS +TRVAIGTRMRLMGNVTRAIVA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas argentinensis TaxID=289370 RepID=A0A1I3I3G2_9PSED +---LLERLQAVAERQDGELGVYVKDLHSNLAV-TLRADERWYMASGIKVPVAIAVLRGVE +RGDWQLDTRLPLAANDFVDGAGSTNQHGPGELSVRFLLEQMIIYSDNTATDRLIRLA-GL +DTVNALVRELVPEGFEPITTLGDVRRNYYRSNLNAATLSAYGGLLERLASGQALGKAQTD +YLLEVMGRVKTGRQRIVAGLPKDARFAHKTGTQR-ARICDSGLIEAPARAEPVLVVACVQ +GQQSLAKAERSLRQVGEALT--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Phenylobacterium sp. SCN 69-14 TaxID=1660128 RepID=A0A1D2TR45_9CAUL +------------------------------------------------------------ +-------------QADMISHAPVTEPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL +DALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLLVDTPLSPASKT +LLMRWLVDTPTGQGRIKAGVPAGWTVAHKTGTGGYGPVNDIGLILPPNAAPIAIAVYFHA +TKSTDAQREAVIADATRQALK-- +>[subseq from] serine hydrolase n=1 Tax=Spirosoma sp. 209 TaxID=1955701 RepID=UPI00098CF9C6 +--------------ASARVSVAVESLADSSVSfAHRADERVPSASVIKLPILLEAMERVK +AGTLDLDEIHILTDTEKVGGDGVLKTYSHRSIAYRDLLRLMMVYSDNTATNIFINEL-GM +DAINARIRAVGLPRSQLNRVMMDTLAA-RQGRDNYVTCLEMNRLLKKIYHRQVATPELCE +QMLTLLKQNED-TLTIPRLLPPDVVVAHKTGTLSY-IRADVGIVYA--HQPFLLSIFVEG +LP--TAEAERTIAETARICFTYf +>[subseq from] Beta-lactamase n=2 Tax=Sphingobium baderi TaxID=1332080 RepID=T0GFC3_9SPHN +-eRLLAQFQSFAALSDGTVGIAVQDLSTGEEQ-SLNGDTLFPMASTYKVAVAGKILSMAD +AGVLALQDQVPLGPA-----------LPAKARSVHDLIDLMLTHSDNDATDALVARAGGP +AAIDGWVKALGVKALRVDSDTAHLLYAFTLDPRDTATPRAMNALLAAIQLGKALKPASTV +YLLGMMERCHTGKARLKGMLPPSARIAHKTGSLN-GYGGDVGIVTLSDGRMFAISVFVMK +DYRGRETRDRIMA---------- +>[subseq from] Serine hydrolase n=1 Tax=Peptoniphilus sp. HMSC062D09 TaxID=1739305 RepID=A0A1E9AUM7_9FIRM +-nKLRDAIKNIVDESPGSISVTFCDLDEGEKF-SINGNKKSPSASMIKLLIMLTIFKKVE +LGEINLNEKIKLEDENKVDGSGVLKELSCEHFSIRELLTLMIIISDNFATNILIDKV-GM +DDVNKLGRELKLLETSLERKMMDVGAK-EKGHDNYTSSEDVASILKMIYEKSFLSEEMSS +LAIDILLRQQE-RDRLQRYLPEDLKIASKSGDLDN-LENDGGIFFTEAK-NYILVVLVSG +AE-SNVAAKEIIGKISLEIYK-- +>[subseq from] serine hydrolase n=1 Tax=Fusobacterium hwasookii TaxID=1583098 RepID=UPI0004972E15 +-tEWKKEIEKIISQVDGKVCVNFYDLNKNDGF-SINGNEKVLSASMIKLLILAELMKKIS +EDKFSLSDTIMMTNFMKTEGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLRETFLERRMMDAEA-RKNGYDNYTSADDISLLLKLIYQEKLINKEASQ +LMLEILLKQQQ-GERLQRYLPTDIKIAHKCGDLDN-LENDGGIIWLEEK-VYILVVLTSR +MS--NLQCKQTIGKISKFVYDK- +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium 13_2_20CM_55_10 TaxID=1805420 RepID=A0A1Q6V723_9BACT +-kKLETRVEEIAARLDGVMGVAVLDLTDGRVL-LRNADRVFAAASSIKLAILLELYRQDQ +KGKARLDDIYSFDPKDLVEDSRIMAGLTPGVVTNRDLAQFMVAVSDNAAANVLIDRV-GR +DNVNAMLRSLGLSKTVLRRKMMDIAAARRG-DENVATPQEMVRLLEAIFKEKAVDKESTA +GLIKQLSTKK--DSYIPRLLPDDVQIANKPGELE-GVRNDSGIVFAAHR-PFGISVMTAY +DR-DEKAAERAISDVALEAYQYf +>[subseq from] Beta-lactamase n=1 Tax=Gloeomargarita lithophora Alchichica-D10 TaxID=1188229 RepID=A0A1J0A8V3_9CYAN +-qALQAQLLPLTQRNKVTATLYAVDLDSGEYL-DMGGTKTVPAASTIKLPLLLALFQDLD +QGKVRLDERLTMTKPLVASGSGDMQQPVGTTFTLLDTATRMIVISDNTATNMILERLGGK +EVVNQRFQEWGLQTTAVRNLLPDLKGT------NTTSAADLVHTLALIAQGELLSQRSRD +WVLHILRSTEN-RSLLPAGLGKGAVIGHKTGDIGF-IIGDAGVVDTATGQRYLITIFIQS +SYND-PQAVQLLQELSRKSYQY- +>[subseq from] Putative class A beta-lactamase n=1 Tax=Vibrio azureus NBRC 104587 TaxID=1219077 RepID=U3CFJ1_9VIBR +--SLESAIAILEEETSSRIGVSVWDTQSNEWW-DYRGNERFPILGTAKVFVCAAMLDAIE +RNVFSKNTTVTIKPEELTTYSPYVTHWIGQPIKLTSLCEAAALEGDNTAANVIMRELGGP +QSINTFFRSIGDKSTHITQLFPT-NSSLKG---NSSKPNTMVMNLHNIFEGDRLNYEDRE +QIETWMKNTNRKKSRITPALPENWFLAERRGIAHD-SRAELFTIWREEHSPVYVGIYIKD +YDLSLQASGQLLTQVAQLVLREy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X8N8_9BACT +-hELEQRLKTISDGSQGTVGLSVVHIESGKTV-SINGSSQLPLYSVYKLPLAVTVLKDVE +EKRLRLDQKIHVTPQNVVQGTTANSALWQKPYTVEQLLEFSISRSDNTSSDKLVELVGGP +LQVTERMRSLGFQNLDIHISSGEFAKT--RQNPNTGSADDLVQLLVQLHRGKILQPDQVN +LLRGFMQRATTGLHRLRGDLPRGTVVADKTGSGEAKVTNDVGIITLPRGGHLAMAVLVNG +S---------------------- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=candidate division KSB1 bacterium 4484_87 TaxID=1970772 RepID=A0A1W9RJG4_9BACT +------EIENLCADFEATIAVAFEDLQNGASF-FINEKMQMHAASTMKTPVMIEVFKQAE +EGQLSLDDSILVKNESIVDGSKFSYQHLNKNMSIRDLVYQMITVSSNFATNLLIDLV-DA +KNVTATMRSLGAENIRVLRGVEDLKA-YHAGLNNTTDAYDMYLIMKKIALKQVVSPHACD +EMIAILADQRY-KDKIPRFLPSTIRIAHKTGWIS-GIDHDAAIVYMTPDHPYILVVLTKG +IK-NHVQAQELIGKISKTIFDK- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SEM5_9BACT +------------------------------------------------------------ +------------------------------------------SWSDNTAANIVTDAIGGP +QAFTVFMRDIGDQHTRLDRKEPEMNAATPNDLRDTTTPNAIVESLRRIILCDVLREDSRA +LLTDWMINDKVADALLRATLPRTWSIADKSGAGGHGSRSIVAVIWPKNRAPIVVGIYITQ +TTAPMVDSNAAIARLGSVLAD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Solibacillus silvestris (strain StLB046) TaxID=1002809 RepID=F2F4L4_SOLSS +----HKQLDRIIAHCPYKVHVIVEDYKTNEIVwKNRAEEIFSSASIIKVPILIAILAHLQ +KTNGSLNQVFKIAPENMVDFSVITEQK-QIRATLHELLLWMTITSDNTATNVCIDLL-GM +DAFNDYFNEIGLHNTRVQRKMMDFERQ-KLGFDNVTTAQDMQQLFRKIYRGTLLTSEWNA +VALDILSRQRS-HESLKRYIADDVKMAHKTGGLDT-VDHDTGIVFLEVRD-YFIGVFITE +VT-DNDKARQTIGAISKIVYEHf +>[subseq from] serine hydrolase n=1 Tax=Larkinella sp. C7 TaxID=2576607 RepID=UPI0011114DA1 +-eQFRQQIETQLAKQPGRYAVAFKDLTTGQEL-LIHEREEFHAASTMKTPVMIEVYKQAA +QKRFSLSDSILIKNESIVDGSPYSYTKVGTKLPLSAVLYDMIILSSNLATNLIIDLV-DA +KKVMQTMRDMGIRDMQVRRGVEDTK-AFQKGLNNTTTAYDLMLLFEKIATGKAVSPEASQ +DMIRILLDQRF-NSVIPAKLPKTVKVAHKTGSIAS-VRHDSGIVFLPDGRKYVLVLLSKE +IKSD-AAVVESLATVSGMIYQYf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus nitrificans TaxID=651560 RepID=A0A3M8D3H9_9BACL +--SLSTQIAQLVENAGGEWGIYLEDLQTGETL-AFNEHKRFYAASVIKVPIMTAVFAEAY +AGNIALEQKIKLRQEDLVGGAGVLQHMTPGTLTVQDIVTLMIIQSDNTATNILIDLV-GT +ESIRAAMQKTGMTNSQFYNKLMVVPAELEG--YNELTAADMGSHFRYLATGKVISYDSCL +KMMAILKQQQH-RDRIPFHFPPKWELANKTGSVTH-ITHDTGVLFVGSHA-VTICALNKG +LE--QNPAAQTIAEIGRLVYNLy +>[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium periodonticum ATCC 33693 TaxID=546275 RepID=D4CTL1_9FUSO +-tEWKKEIKKIISEVKGQVSVSFYDLDKNMAF-SIDGNKKVLSASMIKLLILAELMRQVS +EAELSLSQKITLTDSMRVGGDGILKVLDSGHFSLKELAKLMIVVSDNEATNIFIDLL-TM +ENINALGRNLALKETFLQRKMMDSNAK-EKGYDNYTSSDDIALLLRLIYEGKLINEETSE +IILDILLQQQQ-SERLQRYLPSDTKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTSA +IP--NLECRETIGKISKYIYS-- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. animalis TaxID=76859 RepID=A0A2B7YSA1_FUSNU +-tEWKKEIEKIISQVEGSVCINFYDLAKNTGF-SIDGDKKVLSASMIKLLILAELVKKVS +ENKFSLSDAITVTEAMKTGGDGVLKELNSEHFTLKELTTLMIIVSDNQATNILIDFL-GM +ENINQLGKELRLKETFLGRKMMDIEAR-KKGYDNYTCADDILSLLKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGNKA-YILVVLTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Serine hydrolase n=1 Tax=Siphonobacter sp. BAB-5404 TaxID=1864824 RepID=A0A2N1KKL1_9BACT +--TLKDQITQYLADKKGTYAVAFKNLQSKQTV-YINEHELFHAASTMKTPVMVEVYKQAA +AGKFAVRDSILVKNESIVDGSTYRYTEVDQKKSIYDLMYQMIIVSSNLATNIIIDLV-GA +EKVTKTFHQLGAKNSQIRRGVEDQK-AYQKGLNNEVTAYDLAELFEKIAKGKAVNKESSK +AMIQILLDQKF-NDIIPAKLPAGTKVAHKTGSITN-IYHDSGIVYLPDGRSYVIVLLSRD +WD-TRENAIQTMATISEMVYQ-- +>[subseq from] Serine hydrolase n=2 Tax=Lysinibacillus TaxID=400634 RepID=A0A2I0UY60_9BACI +----EQIIEKMVQESPYNVHLFVHNLTTNQLLtSHQLETAFSSASVIKVPILIALLSYIE +HNKLSLDTTLPISPDDWVGFSVISEQRLTQ-STLYDLLVWMIITSDNTATNVLIDEV-GM +SFLNDYFRHIGLQDTVLQRKMMDVER-LAQGIDNRTSARDMAHLFTRIYRQELLTAPYSQ +LVIDILSRQRV-HDSLKRYLVEDVKLAHKTGGLDT-VDHDVGIVYSSTID-YSIGVFMTN +VM-DNEQARQLIGRLSKVVYA-- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus sp. Leaf182 TaxID=1736290 RepID=UPI0006FF9B3D +---LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINENQRFYAASVIKVPIMTAVFAEAY +AGKFALEDKIRLRTEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT +ESIRNAMQKTEMTNSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL +KMVDILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG +LE--QKDAAEVMAQIGHLVYHVy +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus porteri TaxID=2126350 RepID=UPI000D0EA6C3 +---LFAQISSLIKDAGGEWGIFFEDLRTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY +AGKFALEDKIKLRAEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNIMIDLV-GT +ESIRNAMQKTEMTNSHFYNKLMVIPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL +KMVAILKTQQH-RDRIPFLLPPKWEIANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG +LE--QKDAADVMAQIGNLVYHVy +>[subseq from] Serine hydrolase n=1 Tax=Ammoniphilus sp. CFH 90114 TaxID=2493665 RepID=A0A4V1NXB6_9BACL +--SLQQKIESIASEAVGMFGVSIKHLNTQEEV-NINENRLFQTASVVKIPILAALMEEAY +KGNIDLHKRMPIREEDFVPGSGVLKEFEGVEVTIKDMATMMIIVSDNLATDKVLGLL-GA +DHVQRRMHESGMQNMYIKHSIWELLSYQESTENNVSTPKDMTRLLEMIAKGEFVSKDCSD +DIIDILLKQQL-RQRIPRLIPYGTKIANKTGSLAT-IVNDAGIVYMPNKGAFVMSVFSKG +VA-SSYDAERTIVQMAQTAYQHf +>[subseq from] serine hydrolase n=1 Tax=Peptoniphilus harei TaxID=54005 RepID=UPI0011DD7284 +--GLQNKIENIVEESSANIFVSFYDLDLGEGF-SINGDQQVPSASMIKILILLKAFDECD +KGKLNLEDTISLDDYERVDGSGILKELYRNHFSIRELLTLMIIVSDNTATNILIDLL-GR +EEINKIGHELGLEKTILQRKMMDSLAK-ERGLDNFTSSNEILKLLKMIYEKNFINEDYSE +LALDILLRQQE-RDRLQRYLPEDLKIANKSGDLDN-LENDGGIFFTKNK-NYILVVLVNQ +AE-SNVLAKEIIGEISLKIYK-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. FJAT-22090 TaxID=1581038 RepID=A0A0M5JCM8_9BACI +--TLVSRIQDLIDQSKGTWAIVLEDLSLGEKW-ELNGDELFYAASVIKVPIMAAVFNAVE +RGEFSLSDQIVLKEEDYVGGSGILQHFTTGTLSIQDIIMLMIIQSDNTATNILIDLV-GI +DSVVQSMNEVGMEKSTFYNKLMMNNPNPK--GFNQISANDIAKLLKQMAIGELVSAKASE +QMINIMKKQQI-KDCLPEKLPTAWELAHKTGWIP-GTRHDVGIFFVGERK-LIATVLSEE +E--DDLVSKRILSEIGEAIYNY- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter sp. CAG:267 TaxID=1262684 RepID=R5YMF9_9PROT +-----AAVEKIADGAGADVGVAYA---SSEKY-RQNGSRQYPLLSVFKLHVAVAVLDRAD +RENIALDSRIQIPSAEIKPYSPLREKYGVRDLPLRELLRYMVAESDNNACDILIRWLGGV +KKVAAYSRKIGLRQTEILVTETEMNRNVRLQYANKAPLSEIIRLLQLIDGGKLFAPELHK +ELLAIMEKTSTGTDKIKKYLPSFVSVAHKTGSSSKIADNDVAIIKSGNN-VWYLAVMVAD +SRLSDKENAEIIARIAFLIYK-- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6G1A0_9BACT +-kKLETRVEEIAGRLDGVMGVAILDLTDGRIL-LRNADRVFPTASSIKIAVLLELYRQDQ +KGKAKLDDIYIFDPKNLVEDSRIMAGLTPGVITNRDLAQFMVAVSDNAAANILIDHV-GM +QNVNATLRSLGLTKTMLRRKMIDIAAARRG-DENVSTPQEMARLLEMIYKEKVLNKEMTT +DFIKQLSTLKQ--SYIPRLLPDNVQIANKPGELE-AVRNDVGIVFASNR-PFVISVMTAY +DR-DEKAAERAISKVALEAYHYf +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5JW90_9BACT +-kKLETRVEEIAARLDGVMGVAVLDLTDGRVL-LRNADRVFAAASSIKLAILLELYRQDQ +KGKARLDDIYSFDPKDLVEDSRIMAGLTPGVVTNRDLAQFMVAVSDNAAANVLIDRV-GR +DNVNAMLRSLGLSKTVLRRKMMDIAAARRG-DENVATPQEMVRLLEAIFKEKAVDKESTA +GLIKQLSTKK--DSYIPRLLPDDVQIANKPGELE-GVRNDSGIVFAAHR-PFGISVMTAY +DR-DEKAAERAISDVALEAYQYf +>[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. JN-9 TaxID=2507159 RepID=A0A410PKS6_9CLOT +-----ENIKRLIDENKGDIAVAFKNLKTNSSI-MINEDVIFPSASTIKLVIIAALMNEIN +KGTMKLEQTITLSDIHKCGGDGILKELKEGHFTLYEIAKLMIIISDNTAANILIKLL-GM +GNINQMAEKLGMANTKLNRKMMDSEA-VKYGKENVTTAKDLCHFLELLYNGKVINKEYSE +IILGVLLKQQL-GGRLNLYLPEGVIIAHKTGDLDK-LEHDAGIVYNYPND-YILCVLTKN +LL-SNKDGKEIIGRVSLEVYKY- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5JP39_9BACT +-kKLETRVEEIAGRLDGVMGVAILDLTDGRIL-LRNADRVFPTASSIKIAVLLELYRQDQ +KGKAKLDDIYTFDPKDLVEDSQIMAGLTAGVVTNRDLAQFMVAVSDNAATNVLIDHV-GM +QNVNATLRSLGLTKTMLRRKMIDIAAARRG-DENVATAQELARLLEMIYKGKALNQELTG +DLIKQLKTLKK-DSYLSYELPADVELADKPGSLD-GVRTDSGIVFAKNR-PFAISVMTTY +DR-DEKAAERAISEVALEAYRYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. AAP5 TaxID=1523415 RepID=A0A4P6XBT4_9SPHN +-----NAVQALGSGFPGQVGIAVRDVTEGWIV-GYNADRLLPQQSVSKLWVAIAVMDAVD +RGRLTLSDIVTVRRSDLTVHQPILPLVGTDGTTIAALLEGAMTRSDNTCNDVLLWKIGGP +PAIRRMLMQKGIAGVGFGPGEWLLQARYLAAPYDGASANGVTLGLARLQRGEVLSSSSTL +HLLTLMAASKTGPLRLKSGLRSGWTFAHKTGTGQSTGYNDVGLLKAPDGHTYAVAVMIGS +TRRPIAARMQFMGNVTRAIIR-- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus camelliae TaxID=1707093 RepID=A0A2N3LM91_9BACI +---LMNEIQDILHRTGGTWGICLEDLDKKQHW-SWNEKEDFFAASIIKVPIMAAVFSAYD +QGQFHLSDKIVLKREDLVGGSGILQHMTPGILTIYDYLTLMIIQSDNTATNVLIDLV-GV +EKIQETMSEIGMKNSCFYNKLMTVPVK--TKGRNKITAGDMAILLHKLTSGSIISQYACE +QMIDIMKKQQF-RDCLPEQFPSEWEFANKTGWVT-GIHHDIGVLYVGNRT-MNIVVLSKD +VEN--RLAKQTMAQIGKCIFNY- +>[subseq from] Beta-lactamase class A n=1 Tax=Mesorhizobium plurifarium TaxID=69974 RepID=A0A0K2VU99_MESPL +--NVTAEISRHSLGAEGYVGVAAWRLDGGPAL-LLNADQPFPMASTFKIAVACRILERIA +TGELGCDHLLEVPDDIRVPGSVIADRFIHPGLSVHNLLQVMLDESDNTATDVLIEACGGV +ATVTRSLEAWGVVGQRVDRDVRGLLRAFEDDLRDVSTPFAMSTLLAELFSDRLPLANLAT +VLRDIMRACRTSGTRLRGLLPPGTEVIDKTGTLG-GVTNDVGLIVLPQGGEIVISVFIKK +GCAPFEQQERVIAEIARTVYDFf +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium RIFCSPLOWO2_12_FULL_66_21 TaxID=1797191 RepID=A0A1F2TUC0_9BACT +-sDLEARLRGPIAASGAEVALAYRTLDGSAEL-LIDADKPFHAASTMKVPVMIELFRRAR +AGTLSLDDRLPIVNESIVDGSPFRYAAVGKTMTLRHLCELMITVSSNFAANLLIEKL-GA +EHIRKTVATLGADGMQVLRGVEDQK-AFDKGLNNTTTARGLLVLLDKIAHGQAVDRAADD +EMLAILERQHF-SDAIPGGLPPGTVVAHKTGTITR-IHHDAAIVYAS--RPYVLVVLVRG +LD-DQKKAAALIAEISKIVFE-- +>[subseq from] Uncharacterized protein n=2 Tax=Rubrobacter xylanophilus TaxID=49319 RepID=A0A510HGS5_9ACTN +------EAEEAVREHPGIAGFYVRDLESGAGY-GVRPDHVFFSASTIKVPVMIAVYRRID +EGRLDYSDRIVTTEEDWAAGAGWLRWTPGAKSTVEDALWLMITQSDNVATNALVRLVGGP +DYVNRVARSLGARDTVLYWKLSSERAAVP-TLDNRTTPRDMALLLARIRSGEAASRHSCR +EMLGLLEQNDL-EWWIEGGVPPGVKVANKGGWLD-ATYNDAGIVEYEER-PYVLAIFTEY +GP-DLNEGGRYLQRISRAVW--- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5XXL6_9BACT +-kKLETRVAEIAARLDGVMGLAILDLTDGRIL-LHNADRVLPAASSIKLAILLELYRQDQ +QGKAKLDDSYTFAPKDLVEDSRIMAGLTPGVVTNRDLAQFMVAVSDNASANILSDRV-GR +DNVNAMLHSLGLSKTMLRRKMMDVAAA-RRGEENVATPQEMVRLLESIHKGKVLDKQSTA +EFIKQLSTSK--DSYIPRYLPDGVQVANKPGELE-AVRTDSGIVYAQNR-PFAISVMTAY +NR-DEKAAERAISEVALEAYHYf +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. FJAT-22090 TaxID=1581038 RepID=UPI0009EAA634 +--TLVSRIQDLIDQSKGTWAIVLEDLSLGEKW-ELNGDELFYAASVIKVPIMAAVFNAVE +RGEFSLSDQIVLKEEDYVGGSGILQHFTTGTLSIQDIIMLMIIQSDNTATNILIDLV-GI +DSVVQSMNEVGMEKSTFYNKLMMNNPNPK--GFNQISANDIAKLLKQMAIGELVSAKASE +QMINIMKKQQI-KDCLPEKLPTAWELAHKTGWIP-GTRHDVGIFFVGERK-LIATVLSEE +E--DDLVSKRILSEIGEAIYNY- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Candidatus Omnitrophica TaxID=1047005 RepID=A0A2G9YIM0_9BACT +--RLKKTLENKVMNFRGTVGMVVEDLDMEWEI-AFDKDTLIPSASLVKVPIMLSYFYAAQ +DGKISLKDTIILKSSEKVSGSRVLGKEPAGSFTVKELFNPMITQSDNAAANILIDFL-GF +DTLNYYFKKMGLKNTNIARKMLDFEER-REGEENYTTAQDMAYLLEELYHKKFLNKDVSE +KCLELLGQQKI-NDRIPRKLPRGTFVVHKTGLERH-ICHDAGIVFTNKGN-FLICVLVKH +KDRFAKPTKKFISDVTLLTYNYy +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sp. SRS2 TaxID=133190 RepID=A0A0F5PFS0_9SPHN +--DLLNAVQRLGSTFQGRIGISVREIDAGWTV-AFAGDANLPQQSVSKLWVGVATMQQLE +QGRLSSADPITVRRSDLTVHQPLRPLVTANGTTIGKLLELAMTRSANSANDVLLWKIGGP +RTVREMLSRTGITGVGFGPGERELQARYLAAPYDGASPNGVTLGLAMLAKGKLLNPSSTA +RLLALMRASKTGPLRLRSGLQPGWTLAHKTGTGQATGYNDVGILVSPSGRRYAVAVMIAS +THQPIPVRMRLMGDLTRAVIR-- +>[subseq from] serine hydrolase n=1 Tax=Spirosoma luteum TaxID=431553 RepID=UPI0012F8B7D6 +--------------------------DTTLSF-AHRATVRIPSASVIKLPIMLELMERVE +AGTIKLDAIHSLTEAEKVGGDGVLKTYPDKSVSYRELLRLMLIKSDNTATNILIHLL-GR +DAVNQRIRKLGLERSQLNRVMMDTLAA-RQGRENYVTAQEMNTLLEKVYRYQVATPERCE +EMLAILKQNED-TLTIPRLLPKRVVIAHKTGTLAY-VRGDVGIVYTQ--KPFLLAVFVEG +VP--TPEAERIISEVAMICYTYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q6WWY0_KLEPN +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETE------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Tolypothrix bouteillei VB521301 TaxID=1479485 RepID=A0A0C1NCF5_9CYAN +------QVKKLMSRYSLSPGMFFLDLETGNYL-DIYGEKVFPAASTIKYPILIALFQDID +AGKVKLNDTLVLRRDLKAEGSGVLQKPVGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLARLSVMIDNDKLLTNTSRS +KALGIMRRVEN-RRLLPSGLGKGATIAHKTGTLGI-ILGDAGIVELPTGKRYLAGIFVKR +PFGD-TRAREFISQISKLVYG-- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6KBF2_9BACT +-kKLEARVGEIATRLDGVMGVAILDLTDGRIL-LRNADHVFPTASSIKIAILLELYHQDQ +KGKVKLDDIYTFDPKDLVEDSQIMAGLTPAVVTNRDLAQFMVAVSDNAATNVLIDRV-GM +QNANATLRSLGLTKTMLRRKMIDIAAARRG-DENVATSQEMTRLLEIIYKGKALNKEVTD +QFIKQLKTLKK-DSYLSYELPADVELADKPGSLD-GIRNDSGIIFAPNR-PFAITVMTAY +DR-DEKAAERAIGQVALEAFHYf +>[subseq from] Serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A6B5L0J8_STAAU +------------------------------------------------------------ +----------------MVAYSPILEKYVGKDIALKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGIPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus sp. NRRL NRS-603 TaxID=2126351 RepID=A0A2P7X3B6_9BACL +---LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY +AGKFALEDKIKLRAEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNILIDLV-GT +ESIRNAMQKTEMANSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL +KMVAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG +LE--QKDAANVMAQIGNLVYHVy +>[subseq from] serine hydrolase n=1 Tax=Spirosoma sp. HMF4905 TaxID=2682092 RepID=UPI0012F9431C +--ELRQKIEQEFSKYPGVFAVAFRNVATGEEL-LIREREVFHAASTMKTPVMIEVYKQQA +QGKLSLSDSILIKTESIVDGSPYTYKQIGTKRTLASLVYDMITVSSNLATNLIIELV-GA +PNVLQTMRDLGAKDIQVRRGVEDSK-AFAKGLNNSTTAYDLMLIFDKIATGQAVSPEASK +AMIATLLDQKF-NDAIPAKLPNDVKVAHKTGSIT-GVRHDSGIVLLPDGRKYVLVLLSKD +IK-DDKLTSGVMATVSEWIYRY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V5A1_9BACT +------------------------------------------------FMAASAILKESE +VKKNLLTQHVALKKSDLVNYNPITEKRLNEGMAIGELPAAALQYSDNTAMNKLIEHLGGP +HKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA +QLVEWMKGNTTGAMSIRAGLPATWIV---------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus mangiferihumi TaxID=1130819 RepID=A0A4U2YNK5_9BACI +----QQTIQRIIQEAPYKVHMFVKDFKTNELViNERLDDAFSSASLIKVPILIAVFDYID +VCNIPINQVIAITPSDWVDFSVISEQRVT-SCTIYELCVWMITTSDNTATNVLIDVI-GM +EALNKYFHKIGLTHTQLQRKMMDFER-LAKGIDNITTARDMAHLFSQIYGKNLLSPVLSQ +LAIDILCRQRF-HESLRRYIVDDVTIAHKTGGLDT-VDHDVGIVFSHVQD-YGIGVFISE +VKQN-DVARQLIGRLSKVVYDK- +>[subseq from] Beta-lactamase VEB-1 (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0M3R7M2_PSEAI +------------------------------------------MQSVMKFPIALAVLSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLINTYNNQLLSKKSYD +FFWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium QH_7_62_13 TaxID=1919098 RepID=A0A2T2T870_9BACT +--DLKDQIQTTLDSVEGDFAVAVRTLDDTTETlLLNEHEMFHAASTMKVPVMVELYRQAH +EGRFSLDDSIEVKNESIVNGSPYSYDHIGEKRSIRTLMRAMITVSSNLATNILIEKV-GA +ERTTQTMREYGADSIQVRRGVEDMNA-YRRGLNNETTAHDLLVILERIARGNAVSAEASS +EMIDILRDQEY-NDMIPARLPDSVDVAHKTGRIT-GVRHDGGIVVVPDGPSYVLVLLSKN +LR-DETAGIATLARLSRLVFE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=C7E642_ECOLX +-----------------------------------------------KVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGN--------------------------------------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPHIGHO2_02_FULL_57_9 TaxID=1797943 RepID=A0A1F9U874_9BACT +--AMTEELSLLASKHQGRVAIFLKDLGTGNIW-THHSEDLFPSASLIKVPLMACVFFKIR +DGQLALYDKLTLRRRHRRGGSGSLKWRSDGELTVHELLRHMINESDNTATAMILEVL-GL +NYVQQQFPKLGLVYTGISEEGMSLKSG-RVAQENYTTAREMAMILEKIYRGEMVDRPSSE +IMMDILKHRKAVTSRLAKGLPKGWEIAHKTGLLRH-ACHDAAVILTPHGD-YVMTVLTGQ +NA-SYRTAKNFIDRLGRVTFAL- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8SGR5_9BACT +-eRLQATLLRLSTDLDGVPGYLMRDLASGESL-ERNADIVFPVASVIKLPVLLELYRQAE +EGTLDLARPVPIDPKARVEGGGVLEKWSAPYLSAAQLAVLMMDFSDNYATNLLIDLV-GP +DRVGRRLKGWGFKETLLRRKMMDLDAA-RAGRENVSTPREMAALLERLGRGQILDADGTG +RVIAIMKRNER--TPLKRALPAGIEAADKEGELD-GVRCSVGIVFVPSGR---------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3C0ZKU0_9BACT +--KFVAKIQSIAENADAVVGVAIKDLKSGDEY-LINADEILPQASSIKIHILTELYREAE +QGRYRLTDILQLPESVRVGGSGILSELGPKSLSLHDYAVLMIVLSDNTATNLLIDLV-GM +QNVNKSLQAMGASKTKLQRVMMDVKAA-KAGRENIGTPREAMMVLEKLHQGEIVSKKASE +EIVSILRKPKEG--PIRRGVPESVPVANKEGEVE-GMRCDVAIVELPES-PYIICVMTKL +LLKP-EDGPRVIEELSRASFQYf +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI00114DB686 +----EQIIEKMIQESPYNVHLFVHNLTTNQLLtSHQLETAFSSASVIKVPILIALLSYIE +HNKLSLDTTLPISPDDWVDFSVISEQRLTQ-STLYDLLVWMIITSDNTATNVLIDEV-GM +SFLNDYFRHIGLQDTVLQRKMMDVER-LALGIDNRTSARDMAHLFTRIYRQELLTAPYSQ +LVIDILSRQRV-HDSLKRYLVEDVKLAHKTGGLDT-VDHDVGIVYSSTID-YSIGVFMTN +VM-DNEQARQLIGRLSKVVYA-- +>[subseq from] serine hydrolase n=3 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD40C88 +-hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD +KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP +PALTEFVRSFSDELTRLDRFEPELNEDGPDDLRDTTTPGA-------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Peptoniphilus harei ACS-146-V-Sch2b TaxID=908338 RepID=E4L0E4_9FIRM +--GLQNKIENIVEESSANISVSFYDLDLGEGF-SINGDQQVPSASMIKLLILLKAFDECD +KGKLNLEDTISLDDYERVDGSGILKELYRNHFSIRELLTLMIIVSDNTATNILIDLL-GR +EEINKIGHEFGLEKTILQRKMMDSLAK-EKGLDNFTSSNEILKLLKMIYEKNFVNEDYSE +LALDILLRQQE-RDRLQRYLPEDLKIANKSGDLDN-LENDGGIFFTTNK-NYILVVLVNQ +AE-SNVLAKEIIGEISLKIYK-- +>[subseq from] serine hydrolase n=1 Tax=Solibacillus kalamii TaxID=1748298 RepID=UPI000B3E6F17 +----HKQLDRIIAQCPYKVHVIVEDYKTNEIVwKNRDEEIFSSASIIKVPILIAILAHLQ +KTNGSLNQDFKIAPENMVDFSVITEQK-QIRATLHELLLWMTITSDNTATNVCIDLL-GM +DAFNDYFNEIGLHNTRVQRKMMDFERQ-KLGFDNVTTAQDMQQLFRKIYRGTLLTSEWNA +VALDILSRQRS-HESLKRYIADDVKMAHKTGGLDT-VDHDTGIVFTEVRD-YFIGVFITE +VT-DNDKARQTIGAISKIVYEHf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A059WJK3_KLEPN +------------------------------------------------------------ +-------------------------------------------------MNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPR------------------- +>[subseq from] Serine hydrolase n=1 Tax=Psychrobacillus soli TaxID=1543965 RepID=A0A544SYW7_9BACI +-kTLVNKIRNLTKQSVGTWGIVLEDLDLGEKW-VWNEDELFYAASVIKVPIMAAVFSAVE +RAELALTDQIIIKEEDLVGGSGVLQHLTPGTLSIQDTVMLMIIQSDNTATNVLIDQV-GV +EYIVQTMKAVGMEKSTFYNKLM-MNKPNPK-GFNQITASDVARLLRLIATGELVSPEASE +QMTAIMKKQQI-KDCLPEKLPTSWELAHKTGWIP-GTRHDVGIFYVGERK-LVATVLSKE +ED--DLVSKRILTEIGEEIYNY- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6N867_9BACT +-kKLDARVGEMVQRFDGAMGVAVVDLTDGRAI-LKNADHIFPTASSIKIAILLELYHQDQ +QGKAKLDDVYNFDPKELVEFSQIMAGLTPGVVTNRDLAQFMVAVSDNTAANILIDRV-GK +DNVNAMLGGLRLTKTMLRRKMMDFAAA-RRGEENVSTPQEMTRLLEAIYKGKLLSKELSQ +QLIKQLSTLKE--SYIPHDLPASMQVANKPGNLQN-VRTDSGIVFVKDR-PFAISVMTAD +AR-DERAAEHAISEIALEAYRYf +>[subseq from] serine hydrolase n=1 Tax=Paludisphaera sp. JC670 TaxID=2712865 RepID=UPI0013E9D802 +-------VVALVAPHEAVVEVALHDLATGETV-LIRADEPIHPASTMKVPVMMEVYRRAE +AGGLGLDDEIEVKNTSIVDGSHYAYKRVGGKATIRELVFLMITESSNLATNILVEKL-TG +EAVTAFMKELGAGDLKVLRGVEDDK-AVALGRNNVGTARGTMTILTRLAEGTAVSRSASD +AMLEVLRAQKF-NDGIPAGLPEGTVVAHKTGSFAK-VYHDAGIVEPEGRKPFVLVVMTRG +IEAE-DASRKLVADVARAAYEH- +>[subseq from] Serine hydrolase n=1 Tax=Romboutsia maritimum TaxID=2020948 RepID=A0A371IRP9_9FIRM +----------------------------------------YPSASTIKLVIMGAVMKEIK +EGRINFDDKILLSRDKVCEGDGILKELDEDHFTIKEIMTLMIILSDNTATNILIDLV-GM +DAVNKIGSDMGLKYTKLRRKMMDSE-AVKNGRENTTTPKEMAKILNKIYSEEFIDENFSK +IALDILKRQQV-GNRLTLYMPEDVVVAHKTGDLDK-LEHDVGIVYHELGN-YIICILTKN +LD-TNKNGREVIGKISKLVYENf +>[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus benefaciens TaxID=453960 RepID=A0A2T2XAU8_9FIRM +-------FATWLDAAPGRYGVFALNLVNGKSV-SYHEKDVFPSASTIKVPIMIEVFRRVE +EDHLSLDSLLTLRAEDQVGGSGILFDLTPGSYSLRDLTTLMITVSDNTATNLLIDYL-GV +DAVNATMRRLGAHDTVLERRLQRVPVE--RPTVNRTTPYDLALMMERLAKGECVSLAVSE +RMVSLLKQCQG-PISITAGQPPTVTVAHKTGSLSN-ANHDAGIVYSHDGLAYVAAIMSEG +APHD--TLAPVLRRIGRA----- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus xylanilyticus TaxID=582475 RepID=UPI00083C9188 +----ERTIKQMLQETTYKVHMFVKEPKTEQFFmNERLEEVFQSASLIKVPILLAVLNNLE +SNNKSLEQEMKIAPEEWVDFSVISEQHLEQ-STIYELLVWMIITSDNTATNVLIDFL-GM +DVLNQYFREIGLLHTTIQRKMMDFER-LAKGFDNTTSARDMAHLFLRIYRRDLLSPAFSE +LTLDILSRQRV-HESLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYSNFGD-YLIGVFITE +VTN-NDQARQLIGRISKVVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A355F341_9BACT +---LPGQVERIAKQSRGVVSVAYENLGTGASL-AFQDSEILHAASTMKVPVMMALFEAVD +RGQMRLDAPVRVVNDSIVDGSRYAYAALGQTRTLEELIRRMIVRSSNLATNLLIDQI-GA +SNVTDLMRRLGAYDVTVLRGVEDSK-AFDAGLNNRVSARDLLLLYKKLLDDTTFSRASRE +RMLAILKAQEF-NEKIPAGLPPGTEVAHKTGDIT-AFHHDAAIVFPPGEKPYLLIVLTGG +IA-DEAVADRVIADVSRAVWTY- +>[subseq from] Beta-lactamase n=1 Tax=Cyclobacterium amurskyense TaxID=320787 RepID=A0A0H4PHL8_9BACT +-------------------SYIIQD-KEGNVLsKLNADKKIPSASIIKIPLLIYFMQNVE +EGKVKLSDSYQLKEADKVGGSGKLQYKPTAYATYEYLAKEMIRVSDNTATNILIRKL-GL +QQFQEWLRENGYKTTQLNRFMMDFE-AIALGQQNYLSAEEMNRLLLGLLNGQLLNKASAY +QAIEWLKNCED-DNALPHLLPDGIAVAHKTGTLEY-VRGDAGILYGE--KTIVLTVMVEH +FS-NVANADKIIAEIGRLAYQEf +>[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus borstelensis AK1 TaxID=1300222 RepID=M8D3H0_9BACL +--SLENALSTLLEKSGGQWGIYLEDLQTNEIW-GKGHDDRFYAASVIKVPIMAAVFAEAY +AGKFALEDKLTLRQEDQVGGAGILQHMTPGTWSIYDLTTLMIIQSDNTATNMLIDLV-GA +EAIRSVMNKTGMVNSQFHNKLMIVPAELEG--YNEVTAADLGSHLRHLATGKIISYNSCL +HMINIMKRQQH-RDRIPYHLPPKWELANKTGTVTR-TTHDIGVMYIGNRA-VTICLLSKN +IE--TVAANDVMAQIGRMVYDLy +>[subseq from] Serine hydrolase n=1 Tax=Rufibacter immobilis TaxID=1348778 RepID=A0A3M9N4E7_9BACT +--SLREEVLQELRQQKGTFAVAFKDLQTDEEL-LLNEHESFHAASTMKTPVLIEAYRQAH +QGRFSLSDSLLVKNESIVDGSPFSYKVLGQKRPLSELLYKMIIQSSNLATNLVIEQL-DA +RKVTQTMRELGAKNMQVLRGVEDGK-AYQQGLNNTTTAYDLMVLFQQMARGKTVSPAASQ +EMIRILLDQKF-KDVIPAKLPKEVKVAHKTGWITK-VRHDSGIVFLPDGRKYVLVLLSKD +WDND-SAATAAMANVSQMIYRH- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=A0A0K9YZ86_9BACL +--SLSTSIADLLQEAGGEWGIYLENLQSGEKF-ALNENQRFYAASVIKVPIMTAVFAEAY +AGKLALEDKIKLRREDLVGGAGVLQHLTPGTLTVQDLVTLMIIQSDNTATNMMIDLV-GT +EAIRTAMSKTEMVNSQFYNKLMVVPAELEG--YNEITAADMGSHLRYLATGKVISYDSCL +KMIHILKQQQH-RDRIPSLLPPKWEFASKTGSVTN-ITHDVGILYVGGHA-VTISVLNKG +LK--QKAAADVMARIGSLVYGVy +>[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma oryzae TaxID=1469603 RepID=A0A2T0T0J8_9BACT +----------------VTVSLAVQSLTDSSVAmSVNAERPVPSASVIKLPIMVEVMEQVK +AGTLDLSEIHILTDSEKAGGDGVLKNYSHRSISYADLLRLMLVYSDNTATNIFINEL-GM +AAINARIRAMGLTGTRLNRVMMDTVAA-RQGRDNYVTAADMNRLLSQLYRHRLATPALCE +QMLDILKQNED-TLTIPRLLPKSVVVAHKTGTLAY-VRADAGIVYA--RQPFLLTVLIQG +AP--TPDAERIIAELALICYNAf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A517I7U7_BREBE +---LFAQISSLTKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY +AGKFALEDKIQLRAEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GA +ESIRNAMQKTEMTNSHFYNKLMVIPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL +KMVAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG +LE--QKDAADVMAQIGNLVYHVy +>[subseq from] serine hydrolase n=1 Tax=Ornithinibacillus californiensis TaxID=161536 RepID=UPI00064DFCEF +--ELGDRIQRITDQSTGTWGISLYDLDTNETW-EMNEHHLFYAASVIKVPIMIAAFAANK +RGEFILSDTVELKRENIVGGSGVLQHLTPGTFTIYDLLTLMIIQSDNTATNMMIELV-GV +PSIQQTMKDIGLEKSKFYHKMMTMDVD--REGMNEITASEMAGMLRKLATGKIISVHACE +QMIAIMKQQQI-TNCLPGKVPKEWEIANKTGNVS-GIRHDIGIFYVGKRK-LIASVLTSG +LD--DIQSPDILSKVGLEIYQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Cyclobacterium lianum TaxID=388280 RepID=A0A1M7QG25_9BACT +--DLEAAIQDIVEDTAGDFAVAFKLLDSGLQV-LIHEKEVFHAASTMKTPVMIEIFRQVH +AGKMALEDSVLILNESIVDGSPYSYGRVGQQATVYELMYQMIIKSSNLATNILIEKV-GA +ENVTKTMRDLGAADIQVLRGVEDLKA-FDAGLSNTTTALDMMLIMEAIATGEAVGQEESR +QMMDILYDQYY-KDLIPKLLPDEVKIAHKTGSIT-GVQHDAAILTLPGGTSYVLVILSKN +LS-DVAAGKKAINEISKLIYD-- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI0011AAB929 +----ENQIQDLIQKTPYNVHLFVKDPKTEQFLfSHQIEESFSSASIIKVPILLAVLAYIE +KHNISLHSPLTISPADWVDFSVISEQHLTQ-STVYELLVWMIITSDNTATNVLIDAV-GM +EFLNDYFHQIGLQETLLQRKMMDVER-LAMGIDNFTTARDMAHLFTRIHQQDLLASPYNR +LVIEILSRQRV-HEGLKRYLVDEVKLAHKTGGLDT-VNHDVGIVYSSSID-YMIGVFITN +VT-DNDLARQLIGRLSKVVYDH- +>[subseq from] Serine hydrolase n=1 Tax=Vitiosangium sp. GDMCC 1.1324 TaxID=2138576 RepID=A0A2T4VVJ5_9DELT +---LRADLQAIAQVKGASVAVAYQQLGDAKDSlYLEADRSFHAASTMKVPVMIELFRQAD +AGKLALDQQVPLVNQSIVDGSPYAYERLGKPVPVRELVERMITRSSNLATNTVIALV-DP +KRVTKTLRSLGATTMTVLRGVEDGK-AYEKGLNNTTTARDLATLMAAIERGQVASPDSTK +AMRSILLAQEL-NQEIPAGLPPGTPVAHKTGQIS-GVLHDAAIIYPSGRPPYILVVLTSG +IP-DEKVARSLIVDLSRRVYSH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A345GSJ2_KLEPN +------------------------------------------------------------ +------------------------EKNLADGMTVGELCAAAITMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVA------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. FJAT-22090 TaxID=1581038 RepID=UPI00119F9958 +--SLQKIIESYVTNIEADFGIYIKHLETNEEV-NIQGDKLFQTASVMKLPVLATLYEKAY +KGEINLQQRIQLTEQDYVPGSGVFQEMEYGIPTIKDLATMMIIVSDNLATDKLLKILGGV +NPVKETMDRLGLKNIYIKHSIWELLSYQHNKESNVSSAKDMSLLLELFAKGEFVSTKCSR +EIIDILHRQHY-QQRIGGLLPRNTPVANKTGSLG-AMYNDAGVVYLPDKGQYVICVFSNG +HSLE-YEGDEPIAQISKIAYEYf +>[subseq from] serine hydrolase n=1 Tax=Marinobacter fonticola TaxID=2603215 RepID=UPI0011E7D310 +------------------------------------------------------------ +----------------------------------------------------------GD +ARVNALAKVLGVSRNEFAQTLDEAFAIYYHTGLNSGRLSAYSRFLEKLVNGDLLEKESQA +YLLNTMERIKTGDNRIVAGLPPDVSFAHKTGTQYR-RACNIGIATHGDGQRVIIAVCARG +TR-NLTDTERAMRQVGEAIT--- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacteroidales bacterium TaxID=2030927 RepID=A0A316MI51_9BACT +-kSMEQQISEYIDGKDARIGVAVI-VDGADTI-AVNGTKDFPMLSVYKFPQAITVADYCT +RNAIELSDIIDILPSELSEWSPLRDKYGVTRLPVNELLAYTLQQSDNNACDILFRLAGGP +LAADSLMKSMGYPDINVASTEDEMHRDTDLCYLNHSTPLEMSRLVDRFYRDLSHSSPECA +EIARLMESCSTGADRLAKPLARGVTIGHKTGTGDRNGVNDVGYIKIPGGRSYSISVFIAD +SAYDIAGTSAIIADISEIVF--- +>[subseq from] serine hydrolase n=1 Tax=Paludisphaera sp. JC665 TaxID=2711216 RepID=UPI0013EC5F19 +--------------SGAVVEIALHDLETGRAH-LIRADEPIHPASTMKVPVMLEAYRQAE +AGLIKLDDQLEIKNQSLVDGSPYTYKRIGGKAAVRELVLLMITESSNLATNILIEKL-GA +VNVTNFMKKLDAGDLKVLRGVEDDK-AFAAGMNNVGTARGLMTILTRLAEGTAVSKTADA +AMMDVLRAQKF-NDGIPAGLPKGTVVAHKTGSITN-VYHDAAVVEPPGRKPFVLVVMTRG +IEAD-HAARKVVAEIARAAYEE- +>[subseq from] Serine hydrolase n=1 Tax=Rufibacter immobilis TaxID=1348778 RepID=A0A3M9N2D2_9BACT +-qKTEQQLKEILEASPALTGLVAVDLTSGETI-SFNPNVVFPQASAIKVPILLEVYQQAQ +AGKFKLTDLRAIAPENRVGGTGIIKDLPDTTFSIRNLAVLMIALSDNTATNTLLDLV-SM +ASINATMQRLGLKQTRVQRKMIQAAAS-GRGEENISTPAEAAKMLQLLYKGEFLNKAASA +EIISILQKTNRETSRLAAGLPASVPLAFKPGVLN-GVSTEWALVLLPER-PYAVAIMENY +KVP--GKAERVLEDVSAVLYQYy +>[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus sp. FJAT-14222 TaxID=1932366 RepID=A0A0M9WWF8_9BACI +----KQTITEILQNAPYKVHMFVKDCKTEQFFiSEKLEDAFSSASLIKVPILLAVLNYLE +SNNKSIEQEIKIAPEEWGDFSVISEQHLEQ-CTIYELLVWMIIKSDNTATNVLIDFL-GM +EALNQYFRQIGLLQTTIQRKMMDFER-LAKDLDNTTSARDMALLFSRIYRKDLLSSAFSE +LTLDILSRQRV-HESLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYNNSRD-YLIGVFVTE +VTNN-DDARQLIGRLSKVVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Pontibacter sp. S10-8 TaxID=1797110 RepID=A0A1Q5PIL8_9BACT +--ALRQQITEELEKQEGTFAVAFKDMATGEEL-LLNERESFHAASTMKTPVLIEAYKQAA +AGKLSLSDSILVRNGSIMDGSMYSYTFVGQKRPVSELLYKMIIQSSNLATNLMIEEL-DA +KQVTQTMRELGAQDIQVLRGVEDSK-AYEQGLNNTTTAYDLMLIFEQIATGKAVNPEASQ +EMIRILLDQRH-REIIPARLPKEVKVAHKTGWIT-GVRHDSGIVILPDGQKYVLVLLSKD +LK-DEKAGMEAMAKVSELVYKY- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI0008536A7D +---LFAQISSLIKDAGGEWGIFFEDLRTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY +AGKFALEDKIQLRAEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNIMIDLV-GT +ESIRNAMQKTEMTNSHFYNKLMVIPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL +KMVAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG +LE--QKDAADVMAQIGNLVYHVy +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A317J2Q5_9BACT +--DLKSRIEDSLKTQSGIFALAFKDLSSNKTI-FINEHTIFHAASTMKTPVLVEVYNQVN +QHKISLNDSIVLKNESIADGSPFTYTHLGEKRSLSQLLYQMITVSSNFSTNLVIDRV-GA +NNVTETMRKLGLRDLQVLRGVED-NKAYAKGLNNIVTAYDLMILFEKIAKGKAVNPASSK +EMIKILEDQKF-NEIIPAQLPANVKVAHKTGSFK-GVHHDSGIVFLPNGKKYVIVILSKD +LT-DEEAATRMMAGISGMIYR-- +>[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' 232 TaxID=2014531 RepID=A0A235IY81_9NOSO +--ELKSQVKALMAHYSLKPGMFFLDIETGNYL-NIDGEKVFPAASTIKYPILIALFEQVD +AGNIKLDEKLVMRRDLVASGSGDLQKRAGIKLSVMETVNKMITISDNTASNMIIDRLGGK +AKLNQRFHTWGLKNTVIRNMLGDFKGT------NTTSPADLVRLSALVDQHKLISESSQF +QVLDVLRHCHN-NKLLAAGVGKGGSIAHKTGDIGF-LVGDAGIISLPNGKHYLAGIFVIR +PH-DDERGREFVRQVSRIVYQY- +>[subseq from] Serine hydrolase n=1 Tax=Dyadobacter sp. AR-3-8 TaxID=2576211 RepID=A0A4U6CXY2_9BACT +--DLKQKISTELSKHKGSYAVALKDLTTGEEL-SINELQTFHAASTMKMPVMIEVFKQAS +QGKFKLTDSITIKNESIVDGSSYSYRHIGEKRAIKDLVYEMIIVSSNFATNMVIDLV-GA +KNVTQTMRDLGAKDILILRGVEDAK-AFQKGLNNTTNAYDLRLLFEKMALGKIVSQKACD +AMIKILLDQKF-NDVIPGNLPKDVKVAHKTGGLPN-IQHDSGIVFLPDGRKYVLVILSRD +WE-NEAANRKMLAGISEMIY--- +>[subseq from] class A beta-lactamase n=1 Tax=Paramuribaculum intestinale TaxID=2094151 RepID=UPI0013751C65 +--EMEVSLKTYVHDKDARIGVAVI-INGKDTV-SVNGKRDFPMLSVYKFPQALAVADYCH +KHNISLNDTIRISADDLNPWSPMRDKYGRKDLPLSEILAYSVQQSDNNACDVLFRLIGGP +QVADSLMKCLGYDEIHILNTEDEMYRDPYLCYANRATPLQMASLFDQFYRREMRHDSRLE +ALGAMMMSCNTGNNRLPLPLPTNAMVGHKTGTGGQGGVNDAGYVFLPNKQGYAIAVFVAD +SGYDMAETENIIADISEIVFQ-- +>[subseq from] Uncharacterized protein n=1 Tax=archaeon TaxID=1906665 RepID=A0A6A8ATQ9_9ARCH +---------AAAEEFDGVMGVSIKDLTTGDAL-SVNGDEQFLAASSIKIPILIELYKKAR +VGTLDLGKEVTVPDDVKVGGTGVIKELGNVTLTLQDLITLMITVSDNTATNMLIDVA-VM +DDVNATMKELGLNVTRLRRKMQDYE-AIAQGKENYSTPNEFTRLMEILHTSERLDPWIAE +QALAVLKKPKT--TTINRLLPYDVEIASKYGNMRN-SYCDVALVYHPQN-PYIITVMTKY +IPTDDVRKQDAISEVSKTAYDHf +>[subseq from] serine hydrolase n=1 Tax=Peptoniphilus grossensis TaxID=1465756 RepID=UPI0002FA16BF +-nKLRDAIKNIVDESPASISVTFCDLDEGEKF-SINGNKKSPSASMIKLLIMLTLLKKVE +LGEIDLNEKIKLEEENKVDGSGVLKELSCEHFSIRELLTLMVIISDNFATNILIDKV-GM +DDVNKLGRELNLLETSLERKMMDVGAK-EKGNDNYTSSEDVASILKMIYEKSFLSEEMSS +LAIDILLRQQE-RDRLQRYLPENLKIASKSGDLDN-LENDGGIFFTEAK-NYILVVLASG +AE-SNVAAKDIIGKISLEIYK-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8CEU5_9BACT +--KFEQRLQQISSRVDGVVGYSVLDLTSGDRI-AHLERETFPTASTIKLAIVYELFRQAA +EGRIRLDDTIALDRAKAVGGTGVLSQLGTPTLSVREYATLMVIVSDNTATNVLIDRL-GM +QNISARMQSLGLGATKLRRHMMDTAAARRG-DENVSTPDDIVRLLQAIEKDE---PDASA +----LLKKPK--ESRLRRALPPGVEAADKPGELD-GVRVDAGIVFAKNR-PYALCVMAAF +LT-SEVEGERAIEEMSRAAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium hwasookii ChDC F300 TaxID=1307444 RepID=A0A0S2ZH51_9FUSO +-tEWKKEIEKIISQVDGKVCVNFYDLNKNDGF-SINGNEKVLSASMIKLLILAELMKKIS +EDKFSLSDTIMMANFMKTEGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLRETFLERRMMDAEA-RKNGYDNYTSADDISLLLKLIYQEKLINKEASQ +LMLEILLKQQQ-GERLQRYLPTDIKIAHKCGDLDN-LENDGGIIWLEEK-VYILVVLTSR +MS--NLQCKQTIGKISKFVYDK- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas oligophenolica TaxID=301154 RepID=A0A502C1D9_9SPHN +--DLLNAIQALGTVFHGRVAITVRDIDEGWAV-AYHGDTLFPQQSVSKLWVAIAVMEAID +RGTLSLADPVTVRRSDLTVHQPIRPLVGKNGTTIAKLLEGAMTHSDNTCNDVLLWKVGGP +PAIRRMLQRKGIKDVGFGPGERILQARYLAAPYDGASANGVTLGLALLNRNALLSRRSTA +YLLSRMRASKTGPLRLRSGLRSGWTLAHKTGTGQSTGYNNVGILRSPNGHYYAVAVMIAS +TRRPIPARMRFMGNVTRAVIR-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V2RDB7_9BACT +-kKLEMRVEEIADRLDGVMGVAILDLTDGRIL-LRNADRVFPTASSIKIAILLELYRQDQ +KGKAKLDDIYTFDPKDLVEDSQIMAGLTPSVVTNRDLAQFMVAVSDNAAANILIDRV-GK +DNVNTMLRGLGLTKTMLRRKMMDIAAARRGD-ESIATPQEMLRLLEAISKGKVLDKQSAA +EFIKQLSTRK--DSYIPRLLPESVQVANKPGELE-AVRNDCGIVFAPNR-PFAISVMTAY +DH-DERAAGNAISEVALEAYRYf +>[subseq from] serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=UPI0002137E02 +-tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGDKKVLSASMIKLLILAELMKKVS +ENKFSLSDAITVTEAMKTGGDGVLKELNSGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINQLGRELDLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQEKLINKEASQ +LMLDILLKQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENNGGIIWIEDKA-YILVVLTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Candidatus Melainabacteria TaxID=1897007 RepID=A0A1F6SGB2_9BACT +--RLTNRLKYLAKQYSLEPGIFIWDFSTGQYV-DINADQEFPTASIVKIPILLQLFRRAE +LGFANLNDRMSLAEYNITGGSGYLQYKPVGTFPIHHLARLMIQESDNTATNMILSTVGGI +NELNRVLRSWGFSKTHMSDLLPDLYGT------NVSTPKDMGTMLFNLDNSDFLTLKSRA +AIVDIMSHVRN-RFLIQAGLPDNAQFIHKSGDIGT-MLGDAGIVMLPDGRKYIIVIMVKR +PW-NLYSAKEFIINASKITYNSy +>[subseq from] Uncharacterized protein n=1 Tax=candidate division WOR-1 bacterium RIFOXYB2_FULL_48_7 TaxID=1802583 RepID=A0A1F4TKC6_9BACT +--ALQAKLNHQLAPFKHKVGVAFIDLKTGDIL-QVNGSMEFPAASVAKVPVMAAAYHLVE +LKQLNLAEKLKLRKEDKVGGSGYLQWMKPGTMSLKDLIGLMIMRSDNTATKMLVDRI-GL +GNINQYLQANDIKNTVLNDHTMLVE--PPSNNNNRTCPLDMAYLTLKIQESYGFDKDSSQ +EMLYFMKNQRY-RWGIWRGVPPGTIVADKTGNLT-GILNDVGVVYTKAGN-YVLAIFTRN +FPK-KREGRKIINDVSRLVYEEy +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI00046A831B +----ENQIQDLIQKTPYDVHLFVKDPKTEQFLfSHQIEESFSSASIIKVPILLAVLAYIE +KHNISLHSPLTISPADWVDFSVISEQHLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM +EFLNDYFRQIGLQETLLQRKMMDVER-LAMGIDNFTSARDMAHLFTRIHQQDLLASPYNR +LVIDILSRQRV-HEGLKRYLVDEVKLAHKTGGLDT-VNHDVGIVYSSSID-YMIGVFITN +VT-DNDLARQLIGRLSKVVYDH- +>[subseq from] hypothetical protein n=1 Tax=Kallotenue sp. CFH 73958 TaxID=2592335 RepID=UPI00128BD248 +------QAREAVEDYPGVAGFYAIDLKSGGGY-GVRPDEIFFSASTIKIPVMVAVYRRID +QGKLKYSDSIVTKEEDWAAGAGWLRWTPGAKTTVEDALWLMMTQSDNVATNALTRIVGGP +GYVNEVARSLGAKDTHLFWRLSSERAA-VPSLDNRTTPRDMAKMMQEISAGRAASEFACR +EMIGLMEQNSL-EYWIESGVPQNVKVANKGGWLD-ATYNDVGLIEYEER-PYALAILTKY +APEEMAEGQTVLTNVSKAVW--- +>[subseq from] Class A beta-lactamase n=3 Tax=Muribaculaceae TaxID=2005473 RepID=A0A2V1IW38_9BACT +--EMEVSLKTYVHDKDARIGVAVI-INGKDTV-SVNGKRDFPMLSVYKFPQALAVADYCH +KHNISLNDTIRISADDLNPWSPMRDKYGRKDLPLSEILAYSVQQSDNNACDVLFRLIGGP +QVADSLMKCLGYDEIHILNTEDEMYRDPYLCYANRATPLQMASLFDQFYRREMRHDSRLE +ALGAMMMSCNTGNNRLPLPLPTNAMVGHKTGTGGQGGVNDAGYVFLPNKQGYAIAVFVAD +SGYDMAETENIIADISEIVFQ-- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. HI0063 TaxID=1822240 RepID=A0A165QX19_9SPHN +-sDLTRRIARLADASQGRIGVYAIDLSSGEEV-GVMADQWFPLASTSKVAIAATYLAGVD +QGKWTLSSEWRLPG------------RGGATLPARRHLELMISKSCNDCTDALLDAVGGP +AAVNRWMREAGLTEFMLTRDIATLIRATSIDVNDSATPRAMGQLLAGIYQGKWLSSSSRS +VLMSAMFATTTGKNRMSAALPGSANLAHKTGTLSR-TASDIGLFQTADGRTIAAAIYVTG +QSPSMAYEN-------------- +>[subseq from] Beta-lactamase n=1 Tax=Fusobacterium hwasookii ChDC F128 TaxID=1216362 RepID=J8VHG0_9FUSO +--ELKKEIEKIISQVDGKVCVNFYDLNKNNGF-SINGSEKVLSASMIKLLILAELMKKIS +EDKFSLSDTIMMANFMKTEGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLRETFLERRMMDAEA-RKNGYDNYTSADDISLLLKLIYQEKLINKEASQ +LMLDILLKQQQ-GERLQRYLPTDIKIAHKCGDLDN-LENDGGIIWFEDK-VYILVVLTSR +MS--NLQCKQTIGKISKFVYDK- +>[subseq from] serine hydrolase n=1 Tax=Caenibacillus caldisaponilyticus TaxID=1674942 RepID=UPI00098876E2 +-qQLIQQIEQHVQEAGGTWGIAIEDLNRGETW-RLNGDQPFYAASIIKLPIMAAVYAAAA +RGDFRLSDFLTLKQDDLVGGSGVLQHLTPGILPIADYVMLMIIQSDNTATNMLIDLV-GT +EEIQKAMKALGMENSTFYNKLMTVPVDTPG--RNMITAADVTKLLSTIARGRFVSWYACE +QMIAIMKKQQW-RDGLPAFLPDEWEVANKTGWMT-GIRHDAAIFYVGRR-TLAVTTLSKD +C--DDWAARVAMAKIGKAIYEY- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI0007D89CE3 +---LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY +AGKFAFEDKIKLRTEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT +ESIRNAMQKTEMKNSQFHNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKIISYDSCL +KMVTILKTQQH-RERIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG +LE--QKDAANVMAQIGNLVYHAy +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Acidobacteria (miscellaneous) TaxID=305072 RepID=A0A1Q8AIM2_9BACT +------------KTSGADVAVAFRTLDGRDEL-LIQPDVDYHAASTMKVPVMIELFRQAR +AGTLKLDDQMPVVNESIVDGSPFAYKRIGSRMSYRDLLDAMITVSSNFATNLIIEHL-GP +KNIQRTTDALGATGMHVLRGVED-NKAFAKGLNNTTTARALLTLMEKIAKGDAVDKASSD +EMVAVLKRQTF-IDRIPAGLPPGTPVAHKTGEITK-IQHDAAIVYAP--RPFALVILVRG +LQ-DAKEGSKLAAEITRVLYD-- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Acidobacteria (miscellaneous) TaxID=305072 RepID=A0A1Q7MQ53_9BACT +------------KTSGADVAVAFRTLDGRDEL-LIQPDVDYHAASTMKVPVMIELFRQAR +AGTLKLDDQMPVVNESIVDGSPFAYKRIGSRMSYRDLLDAMITVSSNFATNLIIEHL-GP +KNIQRTTDALGATGMHVLRGVED-NKAFAKGLNNTTTARALLTLMEKIAKGDAVDKASSD +EMVAVLKRQTF-IDRIPAGLPPGTPVAHKTGEITK-IQHDAAIVYAP--RPFALVILVRG +LQ-DAKEGSKLAAEITRVLYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Azospirillum sp. 51_20 TaxID=1896972 RepID=A0A1Q6UAG7_9PROT +--SLAYRLNRLAAGKDCRVGAAVIA---GSHS-FVHGEGKYPLLSVFKLFIAAQVLDKLG +RENTDCKTELTITRDMIDEYSPMRDERRTYPISVARLLEYMVAESDNNAADILLAYAGGA +EQTQAYLNRLGFGGIDVSVSEKEMNADIAKQYVNRASPADVVRFLKTVREGDILTPENRK +FFDKIMTATVTGGDKLKAGLLQGTVFGHKTGSSSRTADNDAGFVILPDGRTYYIAVMVSD +SRMSDRENAALAAEISAVVYN-- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPLOWO2_12_FULL_39_28 TaxID=1797951 RepID=A0A1F9V9Q5_9BACT +-eELKRKIRYQIDHFPGVVGIYIKDLNRGWTI-EVQAEKLFPSASLVKIPIMATLFQAED +QGLISLEDTLALKKKFKTSGSGSLKKRIGTRYTLRALINKMITLSDNTATNMLTDLL-GL +SYYNSSFSQLGLKNTNFSRKIMDLNKR-DQGIENYTTPKDMGLILEMIYNKKL---KNSE +EMLEILKDQKI-NDRLPVSIPSYWPVGHKTGLMRE-CCHDVGIVFAPSST-YIVCVLTQD +IR-RIRRAKSFISEIGHLTALYy +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. SDF0063 TaxID=2133753 RepID=A0A544UZR3_9BACI +---LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY +AGKFAFEDKIKLRTEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT +ESIRNAMQKTEMKNSQFHNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKIISYDSCL +KMVAILKTQQH-RERIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG +LE--QKDAANVMAQIGNLVYHAy +>[subseq from] serine hydrolase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI0012950808 +-hALEARLAELDRRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD +KGVGKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP +PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGA-------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. FJAT-27238 TaxID=1679167 RepID=A0A0K9MD12_9BACI +---LFAQISSLTKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY +AGKFALEDKIKLRTEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT +ESIRNAMQKTEMTNSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKIISYDSCL +KMVAILKTQQH-RERIPFLLPPKWEFANKTGSVTK-ITHDVGILYVGSHA-VTLSILNKG +LE--QKDAANVMAQIGNLVYHVy +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A524HVL2_9BACT +--ALAEALSEPIAASDAEVGVYFRNLGTGDTV-LINADLRLHAASTMKVPVMIQLFRDAE +AGRFDIDQPVPIGMTSIADGSLYDYQKVGSAVPARELIDLMITRSSNLATNILIELA-DA +RRVTATMRSLGADSIEVLRGVEDLKA-YRAGLSNTTTARDLGVILTALAEGRAAGESATA +DMLAILEHQEF-NEGIPAGLPAGTRVAHKTGWIT-AIDHDAAIVYPDGGPPYVLVVLVRG +IE-DHAVSSKLIATLSGITYR-- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI000D10CFAB +---LFAQISNLIKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY +AGKFALEDKIKLRAEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT +ESIRNAMQKTEMTNSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL +KMVAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSLLNKG +LE--QKDAANVMAQIGTLVYHVy +>[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127ST58_9BACT +-----AAVEKITDGAGADVGVAYA---SSEKY-RQNGSRQYPLLSVFKLHVAVAVLDKAD +RENIALDSRIQIPSAEIKPYSPLREKYGVCDLPLRELLRYMVAESDNNACDILIRWLGGV +KKVAAYSRKIGLRQTEILVTETEMNRNVRWQYANKAPLSEIIRLLQLIDGGKLFAPELHK +ELLAIMEKTSTGTDKIKKYLPSFVSVAHKTGSSSKIADNDVAIIKSGNN-VWYLAVMVAD +SRLSDKENAEIIARIAFLIYK-- +>[subseq from] Serine hydrolase n=1 Tax=Psychrobacillus vulpis TaxID=2325572 RepID=A0A544TUZ3_9BACI +--TLQQKIESYIRDIDATFGIYIKHLGTQEEV-NIEGNRLFQMASVFKVPILATLYEKVY +KGEIDLHERVKLLEEDFVPGSGVFQEMEYGIPTIKDLATMMIIVSDNLATDKVMSIVGGA +NSVQEKMHQIGLNNIYIKHTCWELLSFQESTDNNVSSAKDMSLLLEKIALGEFVSTECSR +EIREILFKQHF-QQRIGGLLPRNKKVANKTGSLGT-MFNDAGIVYLPNKGEFVITVYSTG +GSLE-YKGDEPIAHIAEIAYQYf +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Eremiobacter sp. RRmetagenome_bin22 TaxID=2599629 RepID=A0A2W5Z637_9BACT +--RLAPQLMRLASGTRGVVAVSVVDLDSGMSI-AINGDRNLPAASTIKVPVMVEVLRQID +VGKFSFQRTVSLTDADRDCYGSLCTAHWGSQYTVLQLVWTMITVSDNTATNMLIRLV-GR +QHINQTMSGLGLDQTRLGDVIRS-----DGDIRLRTSANDMMRLLGMIAGHRLINAQACD +EMLQILSGQRH-NRLLPAWLPKGLTIAHKTGTLRD-TLNDVGIVELD-GAPYVICVMTTH +LA-DLDAGERFIRRASLLTYRAf +>[subseq from] Uncharacterized protein n=1 Tax=Bryobacterales bacterium TaxID=2026791 RepID=A0A359LZN7_9BACT +--KTLARISEVDAKLDGALGVAAIDLTSGRVL-SYNANSVFPQASSIKIPILIRLFRDAR +AKQVNLDEKITLTERDMVGGSGHLRGLIQKGLTVREVATAMMETSDNTATNKIIAMV-QR +ERVNQLLDELGFANTRLRRIMMDTAAA-GRDEENVSTPLEMARLVEKIYRNEAAAPADCA +EIAGIMKKVKA---EMREAIPVGVDVASKPGGVP-GVAAETGIVYLANR-PFVLSVMSTF +LAP----KTHPVGEVTRAVYSHf +>[subseq from] Beta-lactamase n=1 Tax=Planctomycetes bacterium ETA_A1 TaxID=2528023 RepID=A0A517XUI6_9BACT +--ELADTLAPLLKAHRGRVAVAVKHLKTGAEF-YHQADEPMPTASLIKFPVMVEAFYQAA +DKKIDFGTTLTLKKEHRVPGSGVLTSHFSDGFPLRDAVRLMIAVSDNTATNLVLEQT-GI +RPVNERMAKLGLTETRINAQVFRGSTRTKKYGLGSTTAREMVKLLEMLQENKLVSEEACK +AMIAHLRACDD-TAMFKRYLPPGVLLAHKTGAVSN-ARTQAGIMTLPSG-PVALCVLTNE +NADQDNAAQVLLANVAKAVYDHf +>[subseq from] Serine hydrolase n=1 Tax=Emticicia sp. TH156 TaxID=2067454 RepID=A0A2N4XGY5_9BACT +--QLKNAILARLNPVEGEFALAFKDLQTGQTV-FINEKESFHAASTMKTPVMIEIFKQAK +AGKFKLTDSILVKNESTVDGSPFKYKKTGQQMTIYDLTYQMIIVSSNLATNILIDLV-GA +KNANATMRALGANDIQVLRGVEDSK-AFQSGMNNTVTAYDLMLIFEKLALGEVVSRKDSE +AMIKILLDQKF-NEIIPARLPGAAKVAHKTGSIT-GVQNDSGIIYLPDGRKYVLVILSRK +LT-DVKKGVEALADVSGMIYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium nucleatum subsp. animalis 7_1 TaxID=457405 RepID=A0A140PSV4_FUSNU +-tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGNKKVLSASMIKLLILAELVKKVS +ENKFSLSDAITVTEAMKTGGDGVLKELNSDHFTLKELATLMIIVSDNQATNILIDFL-GM +KNINQLGRELDLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILVVLTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Serine hydrolase n=1 Tax=Oceanobacillus arenosus TaxID=1229153 RepID=A0A3D8Q206_9BACI +-eQLRQHIKRIIKQSGGKWGISIEELGTNNSW-GINEGDLFYAASIIKIPIMTAVFNDYE +NGRLSLSNTLELKREEMVGGSGVLQHSPGTKWTIYDLLTLMIIQSDNTATNMLIDVI-GM +ESIQQMMKDIGMQDSKFYNKLMTVPATIQG--YNQVTAQELTMMMKKIAMGKIISMHACE +QMIAIMKKQQL-TDCLPAKLPPEWQLANKTGFTS-GVRHDIGILYVGDRA-MVATVLSQD +VD--DNRSKDAIAEMGLEIY--- +>[subseq from] Serine hydrolase n=1 Tax=Variovorax guangxiensis TaxID=1775474 RepID=A0A502E085_9BURK +--HLLADLARIDASGKARIGVYVRDLDTGRAI-SYKADQRWYLASMVKVPVAMAVLRGIE +RGDYTLDTEVTLRASDYVDGAGSTNRQPVGQIAIRVLLEQMIIYSDNTASDMLIDLV-GI +AEVNALVASLVPEGFRRITSLGAIRRAYYATGLNSGRLDAYGELMSLLVGGKALSPLSTS +YLLKLMERVATGTNRIKAGLPTGVRFAHKTGTQRR-RTCDAGLVRTNNGQRRVLVVACTR +DEPSLERSEFALMQVGAAIC--- +>[subseq from] Serine hydrolase n=1 Tax=Snowella sp. TaxID=2164131 RepID=A0A2W7B5W6_9CYAN +---LKQKLANLDKKQKIETQAFFIDLDNGKYV-NLAGDTPISAASLIKIPIAIAFFQDVD +AGKIKLNEKLPMGKDVIASGSGDMQYQQGQKFTALETVTKMIAISDNTATNMLIKRMGGK +AVLDQRFQAWGLTHTQIHNLLPDLEGT------NMTSSKDLATVLLKVNQGELISLKSRD +RLLGIMQETKT-RTLLPPGLESGAIISHKTGDIGT-VLGDAGIIDMPSGKRYIQAIIAKR +PYND-IAARTLIQDMSRATYQH- +>[subseq from] Serine hydrolase n=2 Tax=Acidovorax sp. Root217 TaxID=1736492 RepID=A0A0Q8T5E3_9BURK +---LQAELTQVAAQNTAGIGVYVRDLESGIAV-SHRGQERWYLASTVKVPVALAVLQAVE +RGDFTLDTRLRVRASDYVDGAGHTNAKPVGALSIRYLLEQMVIYSDNTASDMLIGLV-GI +RAVNALVEQLVPRGFERITSLADVRRAYYASGLNSGRLDAYADLLELLVNGKVLHAAHTR +YLLSVMERVQTGVHRVQAGLPKTARFAHKTGTQR-ARTCDSGLVTVPGRDQRVIVVACTR +GELSSARSDRALRDVGAALC--- +>[subseq from] Serine hydrolase n=2 Tax=Fusobacterium TaxID=848 RepID=A0A2C6B447_FUSNP +-tEWKKEIEKIISQVEGKICVNFYDLNKNNGF-SINGDKKVLSASMIKLLILAELLKKAS +ENKFSLSDTITITNFMKTEGDGVLKENIGHHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPTDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus xylanilyticus TaxID=582475 RepID=A0A0K9FE55_9BACI +----KQTITQILQKAPYKVHMFVKDCKTEHFYiSEKIEDTFSSASLIKVPILLAVLNYVE +NNNLSLEQEIMIAPEEWVDFSVISEQRLEL-STIYELLVWMIITSDNTATNVLIDFL-GM +DTLNQYFREIGLLQTTVQRKMMDFER-LAKGFDNTTSARDMALLFSRIYRRDLLSSAFSD +LTIDILSRQRV-HESLKRYLVDEVKLAHKTGGLDT-VDHDVGIVYSSSGD-YLIGVFITE +VTN-NDHARQLIGRISKVVYDY- +>[subseq from] serine hydrolase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=UPI00119F6336 +-qRLTESLARIDAAPDGRIGVYARDLASGDSV-SFRAEQSWYLASTVKVPVAIAVLRGIA +RGDYTLDTPVTLRADDYVDGAGSTNRHAVGALPIRFLLEQMVIHSDNTASDMLIGLV-GL +AQVNAVAAEVAPGGFGSITRLAEVRRAYYATGLNTSRLDAYGELLARLADGQLLPPAQTR +YLLGLMERVVTGPQRIRAGLPAGARFAHKTGTQR-GRFCDAGIVQPAGGT-RVLVVACTR +GELSLVRAERALREVGTALC--- +>[subseq from] ClassA n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SGM8_9BACT +-----AAVEKIADGAGADVGVAYA---SSEKY-RQNGSRQYPLLSVFKLHVAVAVLDRAD +RENIALDSRIQIPSAEIKPYSPLREKYGVRDLPLRELLRYMVAESDNNACDILIRWLGGV +KKVAAYSRKIGLRQTEILVTETEMNRNVRLQYANKAPLSEIIRLLQLIDGGKLFAPELHK +ELLAIMEKTSTGTDKIKKYLPSFVSMAHKTGSSSKIADNDVAIIKSGNN-VWYLAVMVAD +SRLSDKENAEIIARIAFLIYK-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas populi TaxID=2484750 RepID=A0A4Q6XT84_9SPHN +--ALLNAVQALGAAFHGKVAISVRDVEQGWMV-AWNGERANPQQSVSKLWVAITVFDAID +HRRLSLTTPVTVRRADLTVHQPILPLVGPDGTTVGALLQCALTRSDNTCNDVLLWKVGGP +AAIRRMLTEKGIRGVGFGPGERVLQARYLAAPYDGATANGVTLGLSLLGQRKLLSPASTQ +RLLSIMLASKTGPLRLKSGLRTGWRMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS +TRQPISARMRLMGNVTRAIIR-- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2G4ICZ4_9BACT +--QMEDSVRLIAKGTDAVVGVAILDLTDRRAF-YLNADAVYPTASTIKLAVLAELYRQHA +RAGATLGDLYTIDGKDVVGGSDIMGGLTAGIVTNRDLATMMMAVSDNAATNVLINRV-GM +DNVNGWLAGLGLKNTRLRRQMMDVQAA-QAGRENTATPRELVLMLEALHKGDILGAPLTD +EFFRMLGTGKM--SYLPRLLPAAVRTANKPGDLD-AVRNDAGIVFVPNR-PFAIAVMTTF +GR-DHREQEMAIARISRTAWSYf +>[subseq from] Uncharacterized protein n=1 Tax=Acetobacter sp. 46_36 TaxID=1896965 RepID=A0A1Q6T199_9PROT +-----AAVEKIADGAGADVGVAYAS--SGK-Y-RQNGSRQYPLLSVFKLHVAVAVLDRAD +RENIALDSRIQILSAEIKPYSPLREKYGVRDLPLRELLRYMVAESDNNACDILIRWLGGV +KKVAAYSRKIGLRQTEILVTETEMNRNVRLQYANKAPLSEIIRLLQLIDGGKLFAPELHK +ELLAIMEKTSTGTDKIKKYLPSFVSVAHKTGSSSKIADNDVAIIKSGNN-VWYLAVMVAD +SRLSDKENAEIIARIAFLIYK-- +>[subseq from] serine hydrolase n=1 Tax=Erythrobacter pelagi TaxID=994320 RepID=UPI00132C6604 +-sDLTRRIARLADASQGRIGVYAIDLSSGEEV-GVMADQWFPLASTSKVAIAATYLAGVD +EGKWTLSSEWRLPG------------RGGATMPARRHLELMISKSCNDCTDALLNAVGGP +AAVNRWMRGAGLTEFMLTRDIATLIRATSIDVNDSATPRAMGQLLAGIYQGKWLSSSSRS +VLMSAMFATTTGKNRMSAALPGSANLAHKTGTLSR-TASDIGLFQTADGRTIAAAIYVTG +QSPSMAYE--------------- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI00029CAC95 +----EQRITTLIQESPYNVHLFIKNLTTNQLLiSHQLEASFSSASLIKVPILLALLSYIE +KNKLSLDSTLMISPADWVDFSVISEQRLTQ-STFYDLLVWMIITSDNTATNVLIDVV-GM +AYLNAYFQHIGLQDTLLQRKMMDVER-LAKGIDNRTSARDMAHLYTRIYQQELLSPPYNK +LVIDILTRQRV-HDSLKRYLIEDVRLAHKTGGLDT-IDHDVGIFYTNAV-DYSMGVFITN +VT-DNDQARQLIGRLSKVVYDQ- +>[subseq from] Uncharacterized protein n=1 Tax=Psychrobacillus sp. FJAT-21963 TaxID=1712028 RepID=A0A0Q3TQU8_9BACI +--TLVSRIQDLIDQSKGTWAIVLEDLSLGEKW-ELNGDELFYAASVIKVPIMAAVFNAVE +RREFSLSDQIVLKEEDYVGGSGILQHFTTGTLSIQDIMMLMIIQSDNTATNILIDLV-GI +DSVVQSMNEVGMEKSTFYNKLMMNNPNPK--GFNQISANDIAKLLKQMAIGELVSAKASE +QMINIMKKQQI-KDCLPEKLPTAWELAHKTGWIP-GTRHDVGIFFVGERK-LIATVLSEE +E--DDLVSKRILSEIGEAIYNY- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_54_10 TaxID=1797945 RepID=A0A1F9TYU0_9BACT +-tELHQKINYQLRHFPGVAGIYVKDLKTGWTI-EHNSDDLFPSASLVKLPMMAVIYQAQV +SGRLSLDESITLMRNMKARGSGHLRKRPGTRYRVRELIFKMITESDNTATNMLTDRL-DL +DYYNRHFLALGLSRTNLSRMIMDLRRR-DEGIENYTTAKDMGNLLEMIYFKNLT---GSE +EMLDILKHQKI-NDRLALGIPNGWQIGHKTGLMNN-ACHDVGIVFSPTND-YVICVLTTQ +IR-NFRRPKNFISAVSHLVATYy +>[subseq from] Serine hydrolase n=2 Tax=unclassified Nostoc TaxID=2593658 RepID=A0A235HUC2_9NOSO +--ELKSQVRALMTHYSLKPGMFFLDIETGNYL-NIDGEKVFPAASTIKYPILIALFEQVD +AGNIKLDDKLVMRRDLVASGSGDLQKRAGIKLSVMETVNKMITISDNTASNMIIDRLGGK +AKLNQRFHTWGLKNTVIRNMLGDFKGT------NTTSPADLVRLSALVDQHKLISESSQF +QVLDVLRHCHN-NKLLAAGVGKGGSIAHKTGDIGF-LVGDAGIISLPNGKHYLAGIFVIR +PH-DDERGREFVRQVSRIVYQY- +>[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SD69_9BACT +------------------------------------------------------------ +------------KKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD +FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] Serine hydrolase n=1 Tax=Ammoniphilus sp. CFH 90114 TaxID=2493665 RepID=A0A4Q1SYB5_9BACL +--QLVDHVKELTESSGGVWGVVIEDLQTGEEF-RHNAEERFYAASIIKVPIMVAVFDAAN +EGKFHLSDTLALRREDMTSGAGVLQHMTAGTLSIYDLVTLMIIQSDNTATNMLIDLV-GK +KRIREVIKELELSGTVFFNKLQVIP--YPLKGSNQMTAGDAAQLMKRLVTQKVISWQACE +QMIEIMKKQQL-NDFLPSGMPPSWAFAHKTGMVTQ-IHHDVGVLYRNGRA-VLLSVFSRG +LE--TKEARQTMANIGLAVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7UT02_9BACT +-------------ASGAEASVAFRTLDGKAEL-LVRPDVAYHAASTMKVPVMIELFAQAR +KGTLRLDDPLPVKNSSIVDGSPYSYRSVGGTLTLRQLCEAMITVSSNLAANLLIEKL-GV +ESIRRRVHKLGADGMELLRGVEDAKA-FRKGLNNTTTARALLVLLDRIALGKAVDAAASR +QMVDILGRQRF-NDAIPAGLPAGTPVAHKTGSITK-IHHDAAIVYGP--RPFVLVVLVRG +LE-DEKKSKALTADIARAMY--- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A2Z4MG91_BREBE +---LFAQISSLIKDACGEWGIFFEDLRTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY +AGKFALEDKIKLRKEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT +ESIRNAMQKTEMTNSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL +KMVAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG +LE--QKDAAEVMAQIGHLVYHVy +>[subseq from] Class A beta-lactamase n=1 Tax=Dethiosulfovibrio peptidovorans TaxID=47055 RepID=A0A2G6M623_9BACT +---------DRINSLSGTVGLVIEDLQGKNRK-EWNATELFPAASVIKLPILWELFSRVE +KKDFSLQDEVELLEEDKVEGFGILKEHAGLRLSLKDIATLMIVLSDNVATNMLIDLL-GM +DNINDTIESLGLKQTSLQRKMMDSEA-KDRGADNFTSPEDVALLLRHYLENAELSSFSRD +VMLDILLRQQC-NNKLPFRMPPGAPFAHKTGDLP-GTEHDVGILLFPEKT-LLVVVMTKD +LR-DNQKGIIFHNEIGELLYTTf +>[subseq from] Uncharacterized protein n=1 Tax=Psychrobacillus sp. FJAT-21963 TaxID=1712028 RepID=A0A0Q3W401_9BACI +--SLQQKIESYIENIDATFGIYIKHLGTNEEV-NIQENQLFQMASVCKVPILATLYEKVY +KGEIDLQERIKLVEEDYVPGSGVFQEMDYGVPTIKDLATMMIIVSDNLATDKVLSIVGGA +DRVQDRMHQLGLSNIYTKHTIWELLSFQDSTENNVSSAKDMSLLLEKIALGEFVSEECSS +DIREILFKQHF-QQRIGGLLPRNKKVANKTGSLGT-MFNDTGIVYLPDKGEFVITVYSAG +SSLE-YKGDEPIARISEIAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus antibioticus TaxID=2570228 RepID=A0A4U2Y8U0_9BACL +---LFAQISSLTKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY +AGKFALEDKIKLRTEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT +ESIRNAMQKTEMTNSHFYNKLMVIPAELEG--YNEVTAQDMGSHLRYLATGKVISYDSCL +KMVVILKAQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-ITLSILNKG +LE--QKDAANVMAQIGNLVYHGy +>[subseq from] serine hydrolase n=1 Tax=Salinicola halophilus TaxID=184065 RepID=UPI0013A619F5 +------------------------------------------------------------ +-----------------------------------------------------------P +ARLAAISRFIGVPVSDFQRDLSQAFDRYYETGLNAGRLDSVGRLLAMIERGETLSPASTQ +TLLAVMERTRTGANRLRRSWPDDVDFAHKTGTQRS-RFCDGGIASRDEGVRRVVVVTCAK +GTLSMAPAERAMRDVGAAVWE-- +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus halotolerans TaxID=1368476 RepID=A0A3M8HBC4_9BACI +--YLQDRISRLIDEESFDVKVVVKDMDTDNILfEKGIYDVFSSASLIKVPILIAVLDYIE +QRDGLLYQELTITKGNCVDFSVITEQG-QTKSTLYELLVWMIITSDNTATNVLIDFV-GM +DNLNRYFKKIGLTETSVNRKMMDFIRM-EKGIDNVTTAKDMATLFTHIYRKTLLSETYSD +LAINILSRQRI-QDSLKRYFLNDVKMAHKTGSLDT-VEHDVGIVFHPSKN-YLIGVFVTN +HS-SNERAKQLIGRISQTVYQH- +>[subseq from] CARB-like beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q2PPY0_PSEAI +------------------------------------------------------------ +-------------------------------ITLDDACFATMTTSDNAAANIILNALGGP +ESVTDFLRQIGDKETRLDRIEPELNEGKLGDLRDTTTPNAIVNTLNELLFGSTLSQDGQK +KLKYWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEAQSPIIVSIYLAQ +TEASIADRNDAIVKIGRSIFEVy +>[subseq from] serine hydrolase n=1 Tax=Psychrobacillus sp. FJAT-21963 TaxID=1712028 RepID=UPI0009E9B9E9 +--TLVSRIQDLIDQSKGTWAIVLEDLSLGEKW-ELNGDELFYAASVIKVPIMAAVFNAVE +RREFSLSDQIVLKEEDYVGGSGILQHFTTGTLSIQDIMMLMIIQSDNTATNILIDLV-GI +DSVVQSMNEVGMEKSTFYNKLMMNNPNPK--GFNQISANDIAKLLKQMAIGELVSAKASE +QMINIMKKQQI-KDCLPEKLPTAWELAHKTGWIP-GTRHDVGIFFVGERK-LIATVLSEE +E--DDLVSKRILSEIGEAIYNY- +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Nostoc sp. NIES-2111 TaxID=1973475 RepID=A0A1Z4IH76_9NOSO +--QLDSQIKRLMKRYSLSPGMFFLDMETGEYL-DINGEKIFAAASTIKFPILIALFQEID +AGRISPNEILVMRRDLMTGGSGTMQYRKAGSFGLMETASKMMIISDNTATNMIIDRLGGK +NVLNQKFRRWGLQNTVIRNLLGDFKGT------NKTSPKDLVRLAALISRKKLLSSKSNS +QVMSIMTRCSN-RSLLPVGLGKGAKIAHKTGTLGR-VLADAGIIQTPSGKRYLAGIMVAR +PFGD-ARARTFINEVSRLVYG-- +>[subseq from] Serine hydrolase n=1 Tax=Calditrichaeota bacterium TaxID=2212469 RepID=A0A3M1ADU0_9BACT +----SKYLKGLSDSLHAEISVSFYDLQTGQAY-GFADRKMMHAASTMKVPVMIEVFRQAE +AGRFSLHDSLLVKNQSIVDGSPFSYQVIGQKRPIRELVEQMITWSSNLATNLLIEWV-GA +KNVMATLREIGAKDMQVLRGVEDLKA-YRQGLNNRTNAHDLMVVMRALAQKTVASPAACK +QMIDILKHQHW-RTKIPGGLPPGVAVANKTGSIT-AIDHDCAIVFPPQRKPYVLVVLTRG +IA-DHDQAAATIAAISHKIYA-- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium hwasookii ChDC F174 TaxID=1307442 RepID=A0A0S2ZL92_9FUSO +--EWKKEIEKIISQVDGKVCINFYDLNKNDGF-SINGDEKVLSASMIKLLILAELMKKVS +ENKFSLSDTIMMVNFMKTEGDGVLKELNTGHFNLKELATLMIIVSDNQATNILIDFL-GI +ENINLLGKELGLKETFLKRRMMDAEA-RKNGYDNYTSADDISLLLKLIYQEKLINKEASQ +LMLDILLKQQQ-GERLQRYLPTDIKIAHKCGDLDN-LENDGGIIWLEDK-VYILVVLTSR +MS--NLQCKQTIGKISKFVYDK- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=UPI000CCC4E99 +--SLSTSIGDLLREAGGEWGIYLEDLQTGEKF-TWNENQRFYAASVIKVPIMTAVFAQAY +AGKLALEDKIKLRHEDLVGGAGVLQHMTPGTLTVQDLVTLMIIQSDNTATNMMIDLV-GI +EAIRTAMSKTEMVNSQFYNKLMVVPAELEG--YNEITAADMGSHMRYLATGKVISYDSCL +KMIAILKQQQH-RDRIPFLLPPKWEFANKTGSVTN-ITHDVGILYVGSHA-VTISVLNKG +LK--QKTAADVMARIGSLVYGL- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. WG TaxID=1592629 RepID=A0A0W1QGG1_9SPHN +--ALLNAVQALGAGFRGQVAISVRDVDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID +HARMSLATPVKVIREDLTVHQPIRPLVGPNGTTVGALLECALTRSDNTCNDVLLWKVGGP +AAIRRMLKEKGIDGVGFGPGERELQARYLAAPYDGATANGITLGLSLLAQDELLSYGSTD +RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS +TRQPIPVRMRLMGNVTRAIIR-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Aminicenantes bacterium TaxID=2052149 RepID=A0A497DZC0_9BACT +--ELVKTVTSIAQEIKGKVGVYVKHIESGETI-GYNENERFQLASVFKIPLLLTLFKQIH +LGKISLDDRLVLRTKDKTFGSGLLSSMKPGLLSINDLQLLMMAKSDNTATDILYEIV-TP +QAINEYMKELGLKSTKIDYNTRQLILQFDQSDHDTSTPYEIGLLLEKCVKGEIINKEISD +QIVETMKHH-TGAELITRYLPFGVTIARKGGSLAYTVLNDSGIVWLPYKGTLVICIFCNE +LNEVHYELKDKMGRIARAAFDYf +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. SGAir0095 TaxID=2070463 RepID=A0A4P8S5G8_9BACI +-----------GEQLNNNVKLIVNDARTNELLlSKDINDVFSSASLIKVPILLAVLDHLE +NQNQSISQMVKITPDNRVEFSVLTELE-AEEATLHELLVWMIIVSDNTATNVLIDLL-GF +EKLNQYFIKIGLGHTRIRRKMMDFVQ-LESGFDNTTTAKDMALLFTAIYRGELLSKKHSE +LVINILSRQRI-NDSLKRYIADDIKIAHKTGSLET-VEHDVGIVFTEKND-YIIGVFVTE +HTN-NEEAKQIIGKISRIIYGH- +>[subseq from] serine hydrolase n=1 Tax=Rubrobacter sp. SCSIO 52909 TaxID=2653851 RepID=UPI00140D7462 +-----GKLEDRVKGYDGVAGVYVRDLEGDFGY-GVRADETFFSASIIKVPVMVAVYRKVE +KGDLSFSQEVELKEEDWAAGAGWLQWEKAGTQTVGDLLLLMMTQSDNVATNALVRMVGGK +DHVNDVAESLGAKDTLLYQKVSSERGAVPA-LDNRTTPRDMATMMQKIADDEAASEKSCG +YMKDLMRTNEL-DWWLDAGLPADVDAANKAGWLYQ-VYGDVGIVEHEGN-RYAIAILSKH +GSATVDEGAVLIEDLSRTTWE-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=A0A3E4UL47_BACSE +--SLTDTISKIVSEYPGEIGVAVI-INSRDTI-TVNNKSIYPMMSVFKVHQALALCNDFD +SKRISLDTLIRINKGKLDPWSPMLKEHSEPELPIRKLLNYTLIQSDNNVSNLMFKRLLDI +AKTDSFVATIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTDKIISDEKQD +FIKNTLKECKTGTDRIAAPLKEGVVIAHKTGSGDNGAHNDVAFIRLPNNEYYTLAVFVKD +FKGNETQAAKVIARISETVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. polymorphum TaxID=76857 RepID=A0A2C6ATC1_FUSNP +-tEWKKEIEKIISQVDGKVCVNFYDLNKIDGF-SINGNEKVLSASMIKLLILAELLKKAS +ENKFSLSDTITITNFMKTEGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] class A beta-lactamase n=1 Tax=Muribaculum intestinale TaxID=1796646 RepID=UPI00136F62F2 +-sQIEERLKTYVAAQDTRIGVAVI-IDGKETI-SVNGNRDFPMLSVYKFPQALAVADYCM +KKGITLSDTIGIQAKEIKEWSPMRNKYGVSDLPLSEILEYSLQQSDNNACDVLFRLIGGP +QVSDSLMKASGYGDITIGSTEDEMHRDPYLCYQNRATPIAMARLFDKFYRLEMHDNPVHE +AVGAMMMLCGTGDNRLPAPLATDAVIAHKTGTGGRNGINDAGYVFLPNGRGYAIAVFIAD +SAYDMARTEKIIADISKIVYQ-- +>[subseq from] serine hydrolase n=1 Tax=Solibacillus isronensis TaxID=412383 RepID=UPI0009A73C64 +----HKQLDRIIAQCPYKVHVIVEDYNTNEIVwKNRGEEIFSSASIIKVPILITILAHLQ +KTNSNLNHIYEIVPENMVEFSVITEQRQ-IRATLHELLLWMTITSDNTATNVCIDLL-GM +DAFNNYFKEIGLHNTRVQRKMMDFERQ-KLGFDNETTAEDMQHLFRQIYRGTLLTKEWNA +IALDILSRQRS-HESLKRYIVDDVKMAHKTGGLDT-VDHDTGIIFTKERD-YFIGVFITE +VT-DNEKARQLIGTISKIVYDHf +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. polymorphum TaxID=76857 RepID=A0A246EI18_FUSNP +-tEWKKEIEKIISQVEGKVCVNFYDLNKNNGF-SINGNEKVLSASMIKLLILAELLKKAS +ENKFSLSDTITITNFMKTEGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGGKA-YISVILTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6CYV9_9BACT +-kKLEARVDEIAQRFDGVMGIAIVDLTDERAI-LKNADQVFPTASSIKIAILLELYRQEQ +QGKAKLDDTYTFDAKDVVDGSQIMTGLTSGVLTNRDLAQFTVAVSDNAAANVLIDRV-GM +QNVNATLRNLGLTKTTLRRKMMDIAAA-KRGEENVSTPQEMTRLLEAIHKGKALDKELAN +AFMKQLSTKKE--SYIPRRLPPDVDVANKPGDLD-GVRTDSGIVFAKNR-LFAISVMTAY +DR-DERAAEGAIAEIALEAFHYf +>[subseq from] Beta-lactamase n=3 Tax=Acidaminococcus TaxID=904 RepID=G4Q6H0_ACIIR +----------------APYGVYFSDLKTGKGY--YRNSVQTPAASMIKVFILAAAYEDIR +DGKLSLTETFTLTDKNVVAGSGVLQGMPKGTVTVKKALDEMIIHSDNTATNLMIDRL-GM +DRVNRYLKEHGYKDTTLRRKMMDFDAA-KKGAENMTTVRDVGLLFKRLYQGKCVSKDLDA +QMLAIYKAQVD-TDMLPDKLPKGTVVAHKTGEVRD-LRHDGGIVYTAKGD-YVLVVFTRD +YTPY-----ASVADLSRRVYDG- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Melainabacteria bacterium MEL.A1 TaxID=1899017 RepID=A0A1D7YSX4_9BACT +---LESQLSNLAAMYSIHPSVYVWDYETGNYV-DMNADEIFPTASIIKLPVLVELFRSIE +KNQLTIYDEMPLTEYYRTEGSGSLQFRAANSYTIDKLARMMITESDNSATNMLMARLGSM +TDINSALREWGLKHTYVQTWLPDLGGT------NHSTARDMAQILYNIDNPKFLSNSSRE +KIFDYMGHVHN-NRLIAAGLPAGATFLHKTGDIGK-MLGDAGIVYAPNGKKYIVVIFANR +PHN-SPLGKEFIVKASQVIYN-- +>[subseq from] Uncharacterized protein n=1 Tax=Tissierella sp. P1 TaxID=1280483 RepID=A0A265Q247_9FIRM +---------------EEKVSIIIKDLTNDQWIlKYDENRTFPSASIIKILIMAEALERVE +KGEFDLEQKIKVRECDRVEYSLVSELKLE-EYPLIDLITLMIILSDNTATNILIELL-GY +ERINEMAKKIGCNDTILRRKMMDFEAA-KEGRENMTSPMDIAILMEKIYNKSIISPEMCE +LMIHILSRQKH-RNMLPRYILDEVVIAHKTGELS-GLNHDIGIFYLENI-HYLIGIFTTD +GK-DDLVGKGTIGKISKLVYDN- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8IYL0_9BACT +--ALRARVLSLIKASGAEVAVAFRTIDGRQEL-LIDPDTTFHAASTMKLPVMIELFRQAE +AGMLSLDDPLPIRNHSIVDGSEYPYKAIGGTLTLRQLAEAMITVSSNFAANLLIERL-GV +ENIRRTVTKIGADGMQVLRGVEDAK-AFEKGMNNTTTARGLLVLLEKLANGPVVSTKADA +DMIAMLSRQTF-NDAIPAGVPAGTRIAHKTGTITK-IHHDAAIVFAP--RPYVLVVLVRG +LQE-EKESAALIAAISREVW--- +>[subseq from] Beta-lactamase VEB-1 (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0M4FJ21_PSEAI +------------------------------------------MQSVMKFPIALAVLSEID +KGNLFFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGKNATNDVGVITLPNGQLIFISVFVAE +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Sphingomonas populi TaxID=2484750 RepID=UPI0013EE7AB0 +--ALLNAVQALGAAFHGKVAISVRDVEQGWMV-AWNGERANPQQSVSKLWVAITVFDAID +HRRLSLTTPVTVRRADLTVHQPILPLVGPDGTTVGALLQCALTRSDNTCNDVLLWKVGGP +AAIRRMLTEKGIRGVGFGPGERVLQARYLAAPYDGATANGVTLGLSLLGQRKLLSPASTQ +RLLSIMLASKTGPLRLKSGLRTGWRMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS +TRQPISARMRLMGNVTRAIIR-- +>[subseq from] Uncharacterized protein n=2 Tax=Pseudomonas TaxID=286 RepID=A0A1E4V439_9PSED +------------------------------------------------------------ +------------------------------------------------------------ +----AVARQLGLAEADLQPSLDQAYQAYYAGGANSAHLTALAEVLEGLADGRALDAAHTD +YLLGLMRQVQTGNQRIRAGLPAATPYAQKTGTQR-ARACDAGLIEPPARAPVLVVACV-R +GDLSMARSERSLRQVGEALT--- +>[subseq from] Serine hydrolase n=1 Tax=Larkinella sp. MA1 TaxID=2607654 RepID=A0A5N1JLZ8_9BACT +-eQLRHQIETQLATQPGRYAVAFKDLTTGQTL-LIHEREEFHAASTMKTPVMIEVYKQAA +QKRFSLSDSILIKNESIVDGSPYSYTKIGTKLPLSAVLYDMIILSSNLATNLIIERV-DA +KKVMQTMREMGTKDLQVRRGVEDTK-AFQKGLNNTTTAYDLMVLFEKIATGKAVSPEASQ +DMIRILLDQRF-NSVIPAKLPKTVRVAHKTGSITS-VRHDSGIVFLPDGRKYVLVLLSKE +IKND-TAVVESLATVSGMIYQYf +>[subseq from] Serine hydrolase n=1 Tax=Larkinella knui TaxID=2025310 RepID=A0A3P1CTX2_9BACT +----------------AHVNVAFESLTDATKF-VHLPDEPVPAASVIKLPILIETMERVK +AGQFDLGKIHVLQESEKTGGSGVLQTYPDQSVTNLEVLTLMMTRSDNTATNILIREL-GM +ENINRRMQTLGLTQSRLNRMMMDTLAA-KQGRENRVSAHEMNVLLKKIYRNEVATPELCA +QMIDILKRNSD-QTTFRLFLPKTAVIAHKTGELAY-VRGDAGIFYVA--KPFLLSVFVQG +TT--TPEAEKIIGEIAQICYNQf +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6DKY8_9BACT +-kKLEARVDEIAERFDGVMGVAIVDLTDDRAI-LKNTDHVFPTASSIKIAILLELYRQEQ +QGKAKLDDIYTFEAKNLVDGSQIMTGLTPGVLTNRDLAQFTVAVSDNAAANVLIDRV-GM +QNVNATLRNLGLTKTMLRRKMMDIAAARRG-DENVSTPQEMMRLLEAIYQGKALDKELAK +AFMKQLSTKKE--SYIPRQLPPDVSIANKPGDLD-GVRTDSGIVFAKNR-PFAISVMTTY +DRE-ERAAESAIAEIA------- +>[subseq from] Class A beta-lactamase n=1 Tax=Muribaculum intestinale TaxID=1796646 RepID=A0A1B1S8Z6_9BACT +-sQIEERLKTYVAAQDTRIGVAVI-IDGKDTV-SVNGNRDFPMLSVYKFPQALAVADYCM +KKGITLSDTIGIQAKEIKEWSPMRNKYGVSDLPLSEILEYSLQQSDNNACDVLFRLIGGP +QVSDSLMKASGYGDITIGSTEDEMHRDPYLCYQNRATPIAMARLFDKFYRLEMHDSPVHE +AVGAMMMLCGTGDNRLPAPLATDAVIAHKTGTGGRNGINDAGYVFLPNGRGYAIAVFIAD +SAYDMARTEKIIADISKIVYQ-- +>[subseq from] serine hydrolase n=1 Tax=Peptoniphilus grossensis TaxID=1465756 RepID=UPI0003016D59 +---LEEKIKSLINEVQGEFGVYFEDTVDGTKI-LLNENIVFSAASTIKIPLVALGLKLYE +EGKFDLNDEIEIKPENRVGGTGVLKTLNRNYPTVSDLMTLAITVSDNVATNQLVDLVGGF +DNINSFSKSLGLNDTKFQRKMLDLKSL-QEGKDNFTTAKDLGTILSLVAKDECVSKESSE +LLLKMMKMQQF-RQKLPNLIPAIVLVANKTGDLWK-VQHDVGIFILPKGERYVISVFSQK +LAED-YEGVETISKISKAAYEY- +>[subseq from] Beta-lactamase n=1 Tax=Brevibacillus panacihumi W25 TaxID=1408254 RepID=V6MDW4_9BACL +--SLSPSIAKILEEAGGEWGVYLEDLQTGEQL-AFNQDERFYAASVIKVPIMTAVFAEVY +AGKFALESKITLRSEDQVGGAGILQHMTPGSWTVQDLVTLMIIQSDNTATNILIDLV-GR +EAIRAAMQATEMTNSRFFNKLMIVPAQVEG--YNEVTAADLGNHLRYLATGKVISYDSCE +RMIAILKQQQH-RDRIPYHFPPSWEFANKTGSVTK-ITHDMGILYIGSRA-VTICVLNKG +LE--QRPAVQSIAKIGKLVFDLy +>[subseq from] Serine hydrolase n=1 Tax=Psychrobacillus sp. AK 1817 TaxID=2303505 RepID=A0A5J6PJF2_9BACI +--SLQKIIESYVTNIEADFGIYIKQLQTNEEV-NIQGDKLFQTASVMKLPVLATLYEKAY +KGEINLQQRIQLTEQDYVPGSGVFQEMEYGIPTIQDLATMMIIVSDNLATDKLLKILGGV +TPVKETMDRLGLNNIYIKHSIWELLSYQHNKESNVSSAKDMSLLLELFAKGEFVSTKCSR +EIIDILHRQHY-QQRIGGLLPRNTPVANKTGSLG-AMYNDAGVVYLPDKGQYVICVFSNG +HSLE-YEGDEPIAQISKIAYEYf +>[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) TaxID=358681 RepID=C0ZAZ5_BREBN +---LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKIPIMTAVFAEAY +AGKFAFEDKIKLRTDDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT +ESIRNAMQKTEMKNSQFHNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKIISYDSCL +KMVAILKTQQH-RERIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG +LE--QKDAANVMAQIGNLVYHAy +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5MEL1_9BACT +-kKLETRIRDIADKFDGVMGVAILDMTDGRIF-SLNADRVFSTASSIKIAVLVELYRQDQ +KGKARLDETYTFHPKDLVEDSRIMAGLTAGVVTNRDLAQFMVAVSDNAAANILIDRV-GK +DNVNATLRAVGLSKTMLRRKMIDIAAARRG-DENVATPEEMVRLLEPIYKGKVLNNEATA +ALTKQLSTLKQ--SYIPRLLPENVQVANKPGELE-AVQTDSGIVFAANR-PFAICVMSAY +DR-DERAAERAISEVALEAYRYf +>[subseq from] Serine hydrolase n=1 Tax=candidate division KSB1 bacterium TaxID=2172550 RepID=A0A6A0HII2_9BACT +haALDHYLEHLTDSLQAEIGVAFRDLETGQEY-FFNEKSMMHAASTMKVPVMIEVFRQAE +AGKFRLEDSVFVRNQSIVDGSPYSYKVIGQKMSVHDLVYQMITVSSNLATNLLIELV-DA +KKVMATLQQLGIHDMQVLRGVEDGK-AYQLGRNNRTNALDLMLSLQAIAEQRAASPAACQ +AMIAILKDQKF-RDSIPAGLPEGFIAANKTGSIT-AINHDAAIILHPNRKPIVLAILTRK +IT-NHEQARATIAGLTRHLF--- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobium lucknowense F2 TaxID=1450518 RepID=A0A081T6X0_9SPHN +--DLLNAVQGLGTSFKGKVGISVRNMDEGWMV-SFNGGRMLPQQSVSKLWVAIAVMDAVD +HGALSLSDPVTVRRSDLTVHQPIRPLVTKAGTTIGKLLEMALTRSANSCNDVLLWKVGGP +EAIRAMLKRKRINDVGFGPGERKLQARYLANPYDGASANGVTLGLMLLKQGKLLSKSSTR +HLLSLMRASRTGPLRLRSGLRNGWTLAHKTGTGQTTGYNDVGILVSPEGHRYAVAVMIAS +TRAPIPARMRLMGDVTRAVIR-- +>[subseq from] Beta-lactamase n=2 Tax=Francisella salina TaxID=573569 RepID=F8G8P6_FRAST +------------------------------------------------------------ +-NKDLLNEKIKILSNQVVGYSPITKEHINQTMTVSQLSRAAI-QSDNTATNLLIEKLGGL +SNLNKFILSLHDHATKVAGLEPIANQVNLTTNQNKTTPKIMARDINKLAFNNILDKKHRL +LFKKWLLGNDSDDNRIAAEIPDEWDVGNKTGTCAYGSTNDVAIIWPDDDRAIIMAIFYTQ +SQENAKPNSKIIREVTKILLDKf +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6FNL9_9BACT +-kKAESRIDEIATRFDGVMGVAIVDLTDARPAlLRNAEHVFPAASSIKLAILLELYHQDE +KGKARLDDLYTFDPKDLVEDSRIMGGLSTGVVTNRDLTQFMVAVSDNSAANVLIDRV-GK +DNVNAMLRGLGLAKTMLRRKMMDVAAAQ-RGDENVATPHEMVQLLEAIYKGKVLKADSTK +ELIKQLSTLKP--SYIPRELPDGVQVANKPGELE-GVRTDSGIVFSANR-PFAISVMTAY +AR-DDRAAERAISDIAQEAYHYf +>[subseq from] Uncharacterized protein n=1 Tax=Actinobacteria bacterium TaxID=1883427 RepID=A0A2N5KJR4_9ACTN +----RRAVEGYEKDHAGIAGAYVVDPEGGLGY-GVRADEPFFGASVMKIPVMIAVYRRMD +EGKLALSDSFKTEKGDWAAGAGWLQWEDPGVHTVEDYLYMMMTQSDNVASNALIRKVGGA +EYVNEVARDLGAENTLIRAKITS-ERAIVTALDNQTTPRDMATMLSEVATGDAASKISCE +DMLDLMYQNVT-DRWLEAGLPNEVYAANKTGWLYK-VYDDAGVVQEGER-PYVVAIFSKH +GPDDVEVGKTLIRDVSWAVWK-- +>[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus sp. FJAT-14745 TaxID=1704289 RepID=A0A0M0X2I9_9BACI +----KQTITQILQIAPYKVHMFVKDCKTEHFFmNEKLEDTFSSASLIKVPILLAVLNYVE +SNNLSLEQEIKITPEEWVDFSVISEQRLEQ-STIYELLVWMIITSDNTATNVLIDFL-GM +DALNQYFREIGLLQTTIQRKMMDIER-LAKGFDNTTSARDMALLFSRIYRRDLLSLAFSE +LTLEILCRQRV-HESLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYSSSGD-YLIGVFITE +VTN-NDHARQLIGRLSKVVYDY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A346QRV6_KLEPN +------------------------------------------------------------ +-----------------------------------------ITMSDNSASNMMLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQ------------- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus boronitolerans TaxID=309788 RepID=UPI0002FF7414 +----EQRITTLIQESPYNVHLFIKNLTTNQLLiGHQLEASFSSASLIKVPILLALLSHIE +KNKLSLDSTLTISPADWVDFSVISEQRLTQ-STFYELLVWMIITSDNTATNVLIDVV-GM +EYLNDYFQHIGLQDTLLQRKMMDVER-LAKGIDNRTSARDMAHLYTRIYQQELLSPSYNK +LVIDILSRQRV-HDSLKRYLVDDVRLAHKTGGLAT-VDHDVGIFYTHAVD-YSMGVFITN +VTEN-DHARQLIGHLSKVVYDQ- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_20CM_2_70_9 TaxID=1805058 RepID=A0A1Q8A776_9CHLR +-----ARLDALARDI-GIVGVSATHLTTRRHI-GVREDELFPTASVIKLPLLVTMYEESL +AGRLDLTERVRYDAGTRVAGSGVLQYLDAGLPTVRDLAVLMMSVSDNTATDLLLERV-GK +GRVEAAMGRYGLRSIRIPFGIREMLMVIPA-QADRSSPRDMCRLLELLARKAILDPPSCD +AILALMERIQS-GTRLPGLLPKGTVVAHKTGSYRR-VRNDVGVVYAPNGA-YAVAIFARE +LVRDNVDDDRALAQLSLAVWEE- +>[subseq from] Beta-lactamase n=5 Tax=Staphylococcus aureus TaxID=1280 RepID=D2J6J5_STAAU +------------------------------------------------------------ +-----------------HNYTDFIEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Uncharacterized protein n=2 Tax=Fusobacterium nucleatum TaxID=851 RepID=D5RB77_FUSN2 +-tEWKKEIKKIILQVEGKVCINFYDLGKNNGF-SINGSEKVLSASMIKLLILAELMKKVS +ENNFSLSDTITITNFMKTEGDGVLKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINFLGKELGLRETFLERRMMDAEA-SKNGYDNYTSADDLSLLLKLIYQEKLINKETSQ +LMLDILLRQQQ-GERLQRYLPPDIKIAHKCGDLDN-LENDGGIIWLGNK-IYILVVLTSG +MS--NLQCRQTIGKISKFVYDK- +>[subseq from] serine hydrolase n=1 Tax=Acidovorax oryzae TaxID=862720 RepID=UPI00047C24F2 +------------------------------------------------------------ +---------------------------------------------------------MGP +QRVQALARTLQVKKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ +MLYRDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHVGVIDPQDGAHAIVVATCAE +GMDEMRQAGRLFEQIGRAITR-- +>[subseq from] Serine hydrolase n=1 Tax=Acidovorax avenae subsp. avenae TaxID=80870 RepID=A0A2R4F2M9_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +QRVQALARSLHVRKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ +MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGARAIVVATCAE +GMDEMRQAGRLFEQIGRAITR-- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. nucleatum TaxID=76856 RepID=A0A101K6N2_FUSNC +-tEWKKEIKKIILQVEGKVCINFYDLGENNGF-SINGSEKVLSASMIKLLILAELMKKVS +ENNFSLSDTITITNFMKTEGDGVLKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINFLGKELGLRETFLERRMMDAEA-SKNGYDNYTSADDLSLLLKLIYQEKLINKETSQ +LMLDILLRQQQ-GERLQRYLPPDIKIAHKCGDLDN-LENDGGIIWLGNK-IYILVVLTSG +MS--NLQCRQTIGKISKFVYDK- +>[subseq from] serine hydrolase n=1 Tax=Xylophilus ampelinus TaxID=54067 RepID=UPI000A05C905 +------------------------------------------------------------ +------------------------------------------------------------ +ARVRKVSQLLDVPASRLRMPLEDAYTAYYASGVNSGRLDAYGELLALLVDGRALGRPMTD +YLLQVMERTATGTRRIKAGLPPDARFAHKTGTQRR-RICDAGLITGPRTAAQVLVVACVR +GDLSLERSERALQQVGAALC--- +>[subseq from] hypothetical protein n=1 Tax=Rufibacter ruber TaxID=1783499 RepID=UPI000AD3F6A4 +-qKTEAEIRRILEASPAVTGLVAVDLTSGETL-QFNQDMVFTQASAIKIPILLEVYNQAH +QGKFKLTDLREINPANVVGGTGILKDLVDSAFSIRNLAVLMITLSDNTATNALIDLV-GM +PHINATLQKMGYKQTKVQRKMIQSAA-SGRGEENISTPAEAARMLQMLHKGEFVNKAVSQ +EIVSVLKKNSRGNSRLAAGVPANVPLAFKPGGLN-GVSTEWALVLLPER-PYAVAIMENY +KV--VGKAETVLEEVSAVLYQYy +>[subseq from] serine hydrolase n=1 Tax=Clostridium symbiosum TaxID=1512 RepID=UPI00093C4F97 +-eELKNRINEFIESQTGNICVALFDLKEQDGF-SIDGDRRVPSASMIKLVIMAELMRRVC +AGELSLEEKIKITQEMRTGGDGVLKEEPGHEFSLREILTLMIIVSDNEATNILIQML-GM +DRINRMAAELGLKEAVLGRKMMDSEA-KKQGRDNFICADDIMLILKKIYEGSCVDRKASA +LMLDILKRQQQ-SGRLQLYLPEDVEVAHKCGDLDF-LENDGGIILLPGH-PYILAVLTNG +VKTNK------------------ +>[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus sp. A1 TaxID=1571920 RepID=A0A0B1XTP0_9BACI +----ENQIQDLIQKTPYKVHLFVKDPKTEQFLfSHQLEESFSSASIIKVPILLAVLAYTE +KHNISLHSALTITPADWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM +DFLNDYFRQIGLQETLLQRKMMDVER-LAMGIDNFTSARDMAHLFTRIYQQDLLASPYNE +LVIDILSRQRV-HEGLKRYLVDDVKLAHKTGGLDT-VDHDAGIVYSSSFD-YLIGVFITN +VT-DNDLARQLIGRLSKVVYDY- +>[subseq from] serine hydrolase n=1 Tax=Peptoniphilus timonensis TaxID=1268254 RepID=UPI00030304C3 +-nKLKKEIEDLVKDSSANISISFYDLDEDEKF-AINGDKKVPSASMIKLLIVLKLLEKVE +RKDLDLEEKIKIQDYEKVDGSGILKELSSNHFSIRELLTLMIIVSDNFATNILIEII-GM +DEVNDLGEKLGLLNTSLQRKMMDLDAK-EKGFDNYTSSHDILKILKMIYEKTFLREDLSD +LALDILLRQQE-RSRLQRFLSEDIKIANKSGDLDN-LENDGGIFFTNKK-NYILVILVNE +AQ-SNVLAKEIIGKISLKIYE-- +>[subseq from] Class A beta-lactamase n=1 Tax=Muribaculaceae bacterium Isolate-007 (NCI) TaxID=2489217 RepID=A0A4Q0IHL1_9BACT +-sQIEERLKTYVAAQDTRIGVAVI-IDGKDTI-SVNGNRDFPMLSVYKFPQALAVADYCM +KKGITLSDTIGIQAKEIKEWSPMRNKYGVSDLPLSEILEYSLQQSDNNACDVLFRLIGGP +QVSDSLMKASGYGDITIGSTEDEMHRDPYLCYQNRATPIAMARLFDKFYRLEMHDSPVHE +AVGAMMMLCGTGDNRLPAPLATDAVIAHKTGTGGRNGINDAGYVFLPNGRGYAIAVFIAD +SAYDMARTEKIIADISKIVYQ-- +>[subseq from] Beta-lactamase VEB-1 (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0M4FJX0_PSEAI +------------------------------------------MQSVMKFPIALAVFSEID +KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCEILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGKNATNDVGVITLPNGQLIFISVFVAE +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Peptoniphilus phoceensis TaxID=1720298 RepID=UPI000782850A +-nKLKKEIEDMVKDSSANISISFYDLDEDENF-AINGDKKVPSASMIKLLIMLKVLEKVE +RKELDLEEKIKIQDYKKVDGSGILKELSWDHFSIRELLTLMIIVSDNFATNILIEIL-GM +DEVNDLGEKLGLLNTSLQRKMMDLDAK-EKGFDNYTSSQDILKILKMIYEKTFLREDLSD +LALDILLRQQE-RSRLQRFLSEDIKIASKSGNLDN-LENDGGIFFTNKK-NYILVVLVNE +AQ-SNVLAKEIIGKISLKIYE-- +>[subseq from] Beta-lactamase class A n=2 Tax=Spirosoma endophyticum TaxID=662367 RepID=A0A1I1YKV1_9BACT +---------------SARVSLSVKSLSDNNVAfKYRADERVPSASVIKLPIMLEAMERVK +AGTLNLDKIYFLKASDKVGGSGVLQNYPDQSVSYRELLRLMMIESDNTATNIFINLL-SR +DAINQRIRTIGLKQSQLNRIMMDTLAA-REGRENYVTAQEMSTLVEKIYRNQVATPKLCL +EMIDVLKQVP-GPLTISRLLPKGTVVAHKTGTLTY-VRGDVGIVYAK--EPFLLSVFVEG +VP--TPEAERIIGELSLICYTYf +>[subseq from] serine hydrolase n=1 Tax=Caulobacter sp. S45 TaxID=1641861 RepID=UPI00131E5B63 +--ALAARLQMLGAGFDGQVGIAVEDVREGWVA-DYNGSILRPQQSVSKLWVALAVFKTAD +FGGLKLSDPVLVRRNDMSVFNQPMQKLLGKDTTIDGLLVGAIAQSDNAANDILVRRLGGS +TAVRRALADERIMGIRTGPEERVLQSAYVADADDGATPLGLVDGLSRLQRGELLSSPSTA +RFLQILASTETGPMRLKAGLGSGWSIAHKTGTGQSTGYNDVGLLTAPDGHTYAVAVMIGA +TRRPIPERQALMADVARAVVAQ- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gastranaerophilales bacterium HUM_2 TaxID=1916214 RepID=A0A292QKT8_9BACT +---LESQLSNLAAMYSIHPSVYVWDYETGNYV-DMNADEIFPTASIIKLPVLVELFRSIE +KNQLTIYDEMPLTEYYRSEGSGSLQFRAANSYTIDKLARMMITESDNSATNMLMARLGSM +TDINSALREWGLKHTYVQTWLPDLGGT------NHSTARDMAQILYNIDNPKFLSNSSRE +KIFDYMGHVHN-NRLIAAGLPAGATFLHKTGDIGK-MLGDAGIVYAPNGKKYIVVIFANR +PHN-SPLGKEFIVKASQVIYN-- +>[subseq from] Beta-lactamase n=1 Tax=Geomicrobium sp. JCM 19037 TaxID=1460634 RepID=A0A061NRZ3_9BACL +-----QTMQSFIEEKNAVFGVSVTHVESGEHF-SARGDDPFQQASVFKVPILLSLLKKVD +RGEIDLTARVTLTQEDEVYGSGILKELSPGLPTFKDLAVLMIIVSDNLATDKILKII-GL +ETVQKDLTDWGFTRTTMDVTTSDLLAFQTHTETNTTTPNEMNQIYERLLAGELLSPSSTS +IALDILSRQHL-NRRIPRYLPKSVQVLHKTGSLAD-HLNDAGIIRIDDHNTLIISIFSRG +HA-STEAGEDDIAHIANRAV--- +>[subseq from] serine hydrolase n=1 Tax=Planctomyces sp. SH-PL62 TaxID=1636152 RepID=UPI0012E95140 +----------------AFVEVALHDLETGATV-LIRADEPIHPASTMKVPVMLEVYRRAE +AGEFGLDDAIEIKNTSLVDGSPYSYKRIGGRAAIRELVFLMITESSNLATNLLIEKV-SG +ESVTAFMKELGAGDLKVLRGVEDGKA-FAKGLNNVGTARGTMTVLTRLAERTAVSKSASE +AMLEVLRAQKF-NEGVPALLPEGTIVAHKTGSITR-INHDAAIVEPPGRKPFVLVVMTRG +IEAD-RDARRLIAEIARAAYDH- +>[subseq from] serine hydrolase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI0009EC031C +------------------------------------------------------------ +----------------------------------------------------------GP +QRVQALARSLHVRKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ +MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGLIDPQDGAHAIVVATCAE +GMDEMRQAGRLFEQIGRAITR-- +>[subseq from] Serine hydrolase n=1 Tax=[Brevibacterium] frigoritolerans TaxID=450367 RepID=A0A3Q9SCN4_9BACI +--TIEHDILGLVETFNGRIAYKIEN-GIGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIRELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNLLTKESRE +KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKMIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Oceanobacillus sp. 160 TaxID=2052660 RepID=A0A345PKT7_9BACI +-eQLSHNIERIIKQSSGKWGIAIEELGTNKSW-GINEEELFYAASIIKVPIMIAVFAAYE +NERLSLSDVLELKIEEMVGGSGVLQYLAPGTLTINDLITLMIIQSDNTATNMLINLI-GK +ENIQQTMKNIGMQKSKFYNKLMTVPANLQG--YNEITAQDLTMILKKLAAGKIVSMHACG +RMIEIMKKQQL-TDCLPAKLPQTWQLANKTGFVS-GVRHDIGIFYVGDRA-MATTVLSQD +LD--DHHSKDAIAEIGLEIYRY- +>[subseq from] serine hydrolase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI0006B2F008 +--PLERALARVEADSGVRIGVYVRDLDTGASA-SLHGAEPWYLASSVKVPVAIAVLRGVE +RGDFTLETSLTLRAADYVDGAGPTNSRPVGTLTVRYLLEQMIIYSDNTATDMLIGLV-GI +GTVNAVVQSLVPRGFGRITSLADVRRTYYATGLNSGHLDAYADLLQALVEGRALDARHTA +YLLSVMERVKTGTQRIKAGLPPGARFAHKTGTQR-ARTCDSGLVTVPRSGPRLLVVACTR +GEPSTARSDRALRQVGIALC--- +>[subseq from] serine hydrolase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI00055FE90B +-----NAVQALGAGFRGQVAISVRDVDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID +HARMSLATPVKVIREDLTVHQPIRPLVGPNGTTVGALLECALTRSDNTCNDVLLWKVGGP +AAIRRMLKEKGIDGVGFGPGERELQARYLAAPYDGATANGITLGLSLLAQDELLSYGSTD +RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS +TRQPIPVRMRLMGNVTRAIIR-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Planctomyces sp. SH-PL62 TaxID=1636152 RepID=A0A142YN72_9PLAN +----------------AFVEVALHDLETGATV-LIRADEPIHPASTMKVPVMLEVYRRAE +AGEFGLDDAIEIKNTSLVDGSPYSYKRIGGRAAIRELVFLMITESSNLATNLLIEKV-SG +ESVTAFMKELGAGDLKVLRGVEDGKA-FAKGLNNVGTARGTMTVLTRLAERTAVSKSASE +AMLEVLRAQKF-NEGVPALLPEGTIVAHKTGSITR-INHDAAIVEPPGRKPFVLVVMTRG +IEAD-RDARRLIAEIARAAYDH- +>[subseq from] Serine hydrolase n=2 Tax=Halomicronema hongdechloris TaxID=1209493 RepID=A0A1Z3HP37_9CYAN +-----------------TQATFMVDLDTGDYV-DVNGSTPVPAASTIKVPILVALLQAID +AGQVTLDQGLTLRQQDLAGGSGLREQPLDTQYPVLEVATQMIVSSDNTATNMIIELLGGA +TALNQQFRQWGLSATVIRSPLPDLGGT------NTTSAQDLVTLMARVNQGELLSLRSRD +RLLAIMQRTDN-RSLIPSAAGNGAIVANKTGDIKS-LLGDVALVDTRSGKRYALAILVQR +PDND-GRAGELIRRITERVQ--- +>[subseq from] serine hydrolase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI000D210B4F +------------------------------------------------------------ +----------------------------------------------------------GP +QRVQALARSLHVRKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ +MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAHAIVVATCAE +GMDEMRQAGRLFEQIGRAITR-- +>[subseq from] Class A beta-lactamase n=1 Tax=Muribaculum intestinale TaxID=1796646 RepID=A0A4S2FWR7_9BACT +-sQIEERLKTYVAAQDTRIGVAVI-IDGKDTI-SVNGNHDFPMLSVYKFPQALAVADYCM +KKGITLSDTIGIQAKEIKEWSPMRNKYGVSDLPLSEILEYSLQQSDNNACDVLFRLIGGP +QVSDSLMKASGYGDITIGSTEDEMHRDPYLCYQNRATPIAMARLFDKFYRLEMHDNPVHE +AVGAMMMLCGTGDNRLPAPLATDAVIAHKTGTGGRNGINDAGYVFLPNGRGYAIAVFIAD +SAYDMARTEKIIADISKIVYQ-- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. N3536 TaxID=2666127 RepID=A0A6B8K3D4_9BACI +--SLQKIIESYVTNIEADFGIYIKHLQTNEEV-NIQGDKLFQTASVMKLPVLATLYEKAY +KGEINLQHRIQLTEQDYVPGSGVFQEMEYGIPTIKDLATMMIIVSDNLATDKLLKILGGV +NPVKETMDRLGLNNIYIKHSIWELLSYQHNKESNVSSAKDMSLLLELFAKGEFVSTKCSR +EIIDILHRQHY-QQRIGGLLPRNTPVANKTGSLG-AMYNDAGVVYLPDKGQYVICVFSNG +HSLE-YEGDEPIAQISKIAYEYf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus choshinensis TaxID=54911 RepID=A0A0Q3WLF1_BRECH +--NLSTQISQLVENAGGEWGIYLEDLHTGEKL-TFQEHQRFYAASVIKVPIMTAVFAEAY +AGNIALEQTIKLRREDLVGGAGVLQHMTPGTLTVQDLVTLMIIQSDNTATNIMIDLV-GT +ESIRNAMKKTEMVNSQFYNKLMVVPAELEG--YNEITAADMGAHFRYLATGKVLSYDSCL +KMMAILKQQQH-RDRIPKHFPPKWEFANKTGSVTK-ITHDTGILFMGSHA---VTICLLN +KGLEQKPAADVMAEIGRLVYDLy +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. BA3 TaxID=2057910 RepID=A0A2N0Y689_9BACI +--TIEHDILALVETFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESQE +RILRALDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKLIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Larkinella sp. MA1 TaxID=2607654 RepID=A0A5N1J9H0_9BACT +---------------QTQVNVAFESLTDSTRF-FHLSDELVPSASVIKIPILIETMEQVK +ARKFDLDKVHVLLASEKTGGSGVLQTYPDDSITNLEVLTLMMTRSDNTATNILIREL-GM +DHINRRMQTLGLTKSRLNRVMMDTLAA-KQGRENRVTAREMNLLLKKIYRNEVATPALCA +QMIDILKRNAD-QTTFRLFLPPSAVIAHKTGELTY-VRGDAGIFYVT--KPFLLSVFVQG +TT--TPEAEKIIGEIAAICYNQy +>[subseq from] Uncharacterized protein n=1 Tax=Peptoniphilus sp. DNF00840 TaxID=1477000 RepID=A0A134APC4_9FIRM +---LQNKIENIVEESSANISVSFYDLDFGEGF-SIDGDKQVPSASMIKLLILLKAFYESD +KGKLNLEDTISLDDYERVEGSGILKELYRDHFSIRELLTLMIIVSDNTATNILIDLL-GR +DEINKIGHELGLEKTILQRKMMDSLAK-EKGLDNFTSSDEILKILKMIYEKDFINEDYSQ +LALDILLRQQE-RDRLQRYLPEDLKIANKSGDLDN-LENDGGIFFTKNK-NYILVVLVNQ +AE-SNVLAKEIIGEISLKIYK-- +>[subseq from] serine hydrolase n=1 Tax=Acidovorax oryzae TaxID=862720 RepID=UPI00035D588F +------------------------------------------------------------ +---------------------------------------------------------MGP +QRVQALARTLQVKKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ +MLYRDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAHAIVVATCAE +GMDEMRQAGRLFEQIGRAITR-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus muralis TaxID=264697 RepID=A0A1B3XL97_9BACI +-qTIENDILALVEAFDGKIAYK-LETDLGDTI-GYHEEDLFQSASLIKIPMIIEGYRQSE +RKKIYLNQPVTIPSKAVTGGSGVLHALSNKVLTVEDLLTLMITVSDNTATNMMMSLL-GF +EEINRCMKDLGLKNTILEREMQDFKA-LKEGRDNTITAEDAITCLKSIHTGDFLTKESQE +RILRVFDNQQL-RDKLPSLMGKEVKVANKTGGIR-GVSHDCAIIRLKSRT-VYAAVLTEN +IK-SEEESRQVISKIGKLIYD-- +>[subseq from] hypothetical protein n=1 Tax=Nodosilinea nodulosa TaxID=416001 RepID=UPI000305B09C +-----GELENLATLTGLTPLAFAVDLDSGQYV-DLGGGEPIAAASTIKMPILVAFLQQVD +AGTMDLNQAMVLREEDVAGGSGTMHSAVGTQYTALEVATHMIVSSDNTAANMMIAALGGM +EALNQTFASWGLEQTLLRNPLPDLDGT------NTTSAKDLALLMALIDQGGLLTPRSRD +RMFSIMQRTEN-ASLIPSGITDGSITAHKTGDIGT-MLGDVALIDVPNGKRYALALLVQR +PDND-GRASELIRRMTTTVH--- +>[subseq from] Beta-lactamase n=1 Tax=Chlorogloeopsis fritschii PCC 6912 TaxID=211165 RepID=A0A3S0Y4H3_CHLFR +--KLYDRIEKISRAAQGRVGVAATVLETGESV-ALNAEQRFPMQSVYKFPIGMAVLAQVD +KGKLKLEQRVRVEKSDFVSHSPIRDNNLQGVLSIAELLKYMVSESDGTACDVLLRLIGSP +KVVTEYLRELGVNDIVVANTDKEIGQDKSVQYRNWTTPEGAIALLRALHEGRGLSKSSQA +LLLRLMIETPTGLQRIKGY----------------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Fusobacterium sp. HMSC065F01 TaxID=1739435 RepID=UPI0008A4892C +-tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGNKKVLSASMIKLLILAELMKKVS +ENKFSLSDAITVTEAMKTGGDGVLKELNSGHFTLKELTTLMIIVSDNQATNILIDFL-GM +ENINQLGKELRLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILVVLTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Elusimicrobia bacterium RIFCSPHIGHO2_02_FULL_61_10 TaxID=1797944 RepID=A0A1F9W9P1_9BACT +-tELHQKINYQIRHFPGVAGIYIRDLKTGWTI-EYNADKLFPSASLVKLPIMAVLYQAQV +AGRLSLDESLPVLRKLKARGSGHLRRRLGSRVSVRELVYKMITESDNTATNMLADRL-DM +DYINRHFLALGLSRTNFARMIMDLRRR-DQGIENYTTAHDMGNLLEMIYSKKLT---GSE +EMLEILKGQKI-NDRLALGVPSEWQIGHKTGLMNN-ACHDVGIVFSPTSD-YVICVLTTN +IR-SFRRPKNFISEISYLAASYf +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536PBV1_9CHLR +--------DSLARDI-GIVGVSATHLTTRRHI-GVREDELFPTASVIKLPLLVTMYEESL +AGRLDLTERVRYDAGTRVAGSGVLQYLDAGLPTVRDLAVLMMSVSDNTATDLLLERV-GK +GRVEAAMGRYGLRSIRIPFGIREMLMVIPA-QADRSSPRDMCRLLELLARKEILDPPSCD +AILALMERIQS-GTRLPGLLPKGTVVAHKTGSYRR-VRNDVGVVYAPNGA-YAVAIFARE +LVRDNVDDDRALAQLSLAVWEE- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536CUF2_9CHLR +--------DSLARDI-GIVGVSATHLTTRRHI-GVREDELFPTASVIKLPLLVTMYEESL +AGRLDLTERVRYDAGTRVAGSGVLQYLDAGLPTVRDLAVLMMSVSDNTATDLLLERV-GK +GRVEAAMGRYGLRSIRIPFGIREMLMVIPA-QADRSSPRDMCRLLELLARKEILDPPSCD +AILALMERIQS-GTRLPGLLPKGTVVAHKTGSYRR-VRNDVGVVYAPNGA-YAVAIFARE +LVRDNVDDDRALAQLSLAVWEE- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536PE01_9CHLR +--------DSLARDI-GIVGVSATHLTTRRHI-GVREDELFPTASVIKLPLLVTMYEESL +AGRLDLTERVRYDAGTRVAGSGVLQYLDAGLPTVRDLAVLMMSVSDNTATDLLLERV-GK +GRVEAAMGRYGLRSIRIPFGIREMLMVIPA-QADRSSPRDMCRLLELLARKEILDPPSCD +AILALMERIQS-GTRLPGLLPKGTVVAHKTGSYRR-VRNDVGVVYAPNGA-YAVAIFARE +LVRDNVDDDRALAQLSLAVWEE- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium sp. CAG:715 TaxID=1262834 RepID=R5DJN9_9CLOT +---LESQLSNLAAMYSIHPSIYVWDYETGNYV-DMNADEIFPTASIIKLPVLVELFRSIE +KNQLTIYDEMPLTEYYRTEGSGSLQFRAANSYTIDKLARMMITESDNSATNMLMARLGSM +TDINSALREWGLKHTYVQTWLPDLGGT------NHSTARDMAQILYNIDNPKFLSNSSRE +KIFDYMGHVHN-NRLIAAGLPAGATFLHKTGDIGK-MLGDAGIVYAPNGKKYIVVIFANR +PHN-SPLGKEFIVKASQVIYN-- +>[subseq from] Serine hydrolase n=1 Tax=Ureibacillus thermophilus TaxID=367743 RepID=A0A4P6USA3_9BACL +-----EQIRTLLKQVDCKTHLFVKDLKTNEYLiAEKMDEVFSSASIIKVPILCAVLHYVQ +EHQLSLNHSVDISPENKVDFSVITEQDLTT-STIYELLYWMTVVSDNSATNVLIDLL-GF +DYLNTYFHNIGLKNTKLQRKMMDFDR-LNQGYDNVTTARDMADLFTMISQQTLLPEKLNR +LAIDILCKQTD-YERLKRYIK-DARIAHKTGSLDT-VCHDVGIVYHRNGN-YIIGVFLTE +VR-DFEMGKRWIGRISKMVYDYy +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas sp. AG1028 TaxID=2572911 RepID=A0A561DWT1_9PSED +---LLERLQAITAKQNGELGVYVKDLHSNLAV-TLRAEERWYMASGIKVPVAIAVLRGVE +RGDWQLDTRLSLEADDFVDGAGSTNQYGPGELSVRFLLEQMIIYSDNTATDRLIRLA-GL +DAVNGLVRELVPEGFEPITTLGDVRRAYYRSNLNAATLSAYGELLERLATGQALGNEQTA +YLLSVMSRVKTGSKRLIAGLPKDARLAHKTGTQR-ARICDSGLIETPQRAEPVLIVACVQ +GELSLSKAERTLRQVGEALTD-- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Melainabacteria bacterium TaxID=2052166 RepID=A0A317IGA4_9BACT +--DLEKRLTDMSLLKGMHTGVFLVEPKTGKYA-DVNGHDQFAAASIIKLPVLVSFLIHLD +RKEIKMDEKLTLRQDLMAAGSGHLQWKVGSKVTVREAAELMITVSDNTATNLLIEALGGK +AGLNEEFARWGLTQTKINNMLGDFEGT------NKTSPYDLVYLLGRIDRGELVSPASRR +WMLAVMERTRI-RTLLPQGIGPGAKIAHKTGDIGC-MVGDAGIITSPLGVRYLIAVQVER +PRND-RRANVLVRNISKEIYN-- +>[subseq from] serine hydrolase n=1 Tax=Acidovorax citrulli TaxID=80869 RepID=UPI0006625689 +------------------------------------------------------------ +----------------------------------------------------------GS +QRVQALARTLQVQKDDLKKTMEEAYDRYYAWGTNTATLAGYGGMLEKLVRGQLLTPPHQQ +MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAQAIVVATCAE +DMDEMRQAGRLFEQLGRAITR-- +>[subseq from] Serine hydrolase n=1 Tax=Psychrobacillus lasiicapitis TaxID=1636719 RepID=A0A544TBQ6_9BACI +--TLKQQIESYIEGIDANFGIYIKHLGTQEEV-NIQGNLLFQMASVFKVPILATLYEKVF +NGEINLQERVPLNEEDYVPGSGVFQEMQYGIPTIKDLATMMIIVSDNLATDKVLSIVGGA +NNVQERMHQMGFKDIYIHHTCWELLSFQDSTENNVSSAKDMSLLLEKIALDEFVSPDCSR +EIREVLFKQHF-QQRIGGLLPRNKKVANKTGSLGT-MFNDTGIVYLPDNGEFVITVYSTG +SSLE-YKGDEPIARISEIAYQYf +>[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4U9LAA2_ECOLX +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWG--------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium CG1_02_37_114 TaxID=1805131 RepID=A0A1J4YVZ0_9BACT +-eKLAKDINVMAKNLPGRVSFVIKDLRTGVCI-KQNADELFPSASLVKVPLMACVYKAAE +DGLLSLDEKLILKRSHRVEGKKLRYCRIGTKLEITRLIELMIDESNNIATNMLTERL-GL +DYINDTFKQFGLKKTNFDRYIMDLKAR-NRGIDNWTTAEEITELLEKIYSRKLVNSKASE +QMLEILMKQEI-RDRIPKWLPKDIQIANKTGYLRQ-TCHDAGIVFSVNGD-FIVCVLTHG +VKKT-KLAKNFIREVGYRTYMQy +>[subseq from] Beta-lactamase class A n=2 Tax=Bacillus TaxID=1386 RepID=A0A561DAM2_9BACI +-qTIEHDILALVETFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE +KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKMIYD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus massiliglaciei TaxID=1816693 RepID=UPI000AA7E597 +-qAIEKEVLQLAEEFNGKFACQIVW--DEEII-DYHSDERFQSASLIKIPMIVEGFRQAE +AKEIYLNQPVTIRREQITGGSGVLHALSDKVLTLEDLLTLMITVSDNTSTNILIDLL-GF +DKINQCCRDLGLKNTVLERKMFDFKAK-KEGKDNFITAADTITSLKAIHTGSVLSKESHE +KILRVFENQQF-REKLPARMGKGVKVAGKTGGIQ-GVSHDAAILRSDTQ-TVYAAVLTEE +IT-SDEDSRQVMGKIGKLLYDE- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas straminea TaxID=47882 RepID=A0A1I1RQV1_PSEOC +---LLERLQAITAKQKGELGVYVKDLHSNLAV-TLRAEERWYMASGIKVPVAIAVLRGVE +RGDWQLDTRLSLEADDFVDGAGSTNQYGPGELSVRFLLEQMIIYSDNTATDRLIRLA-GL +DAVNGLVRELVPEGFEPITTLGDVRRAYYRSNLNAATLSAYGELLERLATGQALGNEQTA +YLLSVMSRVKTGSKRLIAGLPKDARLAHKTGTQR-ARICDSGLIETPQRAEPVLIVACVQ +GELSLSKAERTLRQVGEALTD-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8AP61_9BACT +--KFEQRLQQISSRVDGVVGYSVLDLTSGDRI-AHLERETFPTASTIKLAIVYELFRQAA +EGRIRLDDTIALDRAKAVGGTGVLFQLGTPMLSVRDYATLMVIVSDNTATNVLIDRL-GM +QNISARMQSLGLGATKLRRHMMDTAAARRG-DENVSTPDEIVRLLQAIEKDE---PDASA +----LLKKPK--ESRLRRALPPGVEAADKPGELD-GVRVDAGIVFAKNR-PYALCVMATF +LT-SEVEGERAIEEMSRAAYDYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Oxalobacteraceae bacterium TaxID=1871070 RepID=A0A4Q3JTY0_9BURK +------------------------------------------------------------ +--------------------------------SAAKLLELMIVRSDNVAADQLLASLGGP +GALQQWLRLRGITGIRVDRTIAQLLRDHLADSRDVATPNAMVSLLSKLNNGDVLTDKSRA +LLFALMSRCSTGTRRIRALLPTGTRVEDKTGTLD-GVTNDIGVVTMPDGHRVALAIFARG +GR----DRQLGIAQLARAIYDRf +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A3C1EM50_9BACT +----TQALGALAARHPGRVSIMLKDLKSGRCW-TYHPDDLFPAASLIKVPVMISAFYKIS +EGELSLNEMLVLRRRTRVGGSGSLKWRPDGTLSVSELLIHMINESDNTATAMVLDRL-GI +GWVQQQFPRMGLLYTGIYPEGMSIKGG-RVAHENYTTAREMSMLLEKIYRGEIVDKDSSA +LMLEILKRRKAVPSRLAKGLPRGWEIAHKTGLLRM-ACHDSAIFFTPNGD-YVMTVLTGQ +NR-SYHAAKDFISRLGRITFRYy +>[subseq from] serine hydrolase n=1 Tax=Cyclobacterium sp. SYSU L10180 TaxID=2666137 RepID=UPI001391E23E +--ALEEGILSLMQATEGDFGVAFRMLDSGKEL-LINEKEVFHAASTMKTPVMIELFKQAG +AGKFDLQDSILIVNESIVDGSPFSYERIGEKTTIYELMYQMIIKSSNLATNILIDLV-GA +EKVTQSMRELGAEDIEVLRGVEDLKA-FEAGLSNTTTALDMMRIMEAIALGKV---EGSE +EMMKILSDQYF-KDLIPKLLPADVKIAHKTGSIT-GVQHDAAILELPNGNRYVLVILSKN +LA-DVAAGKETIAEISRLIYDY- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=A0A323TUG7_FUSNU +-tEWKKEIEKIISQVEGKVCVNFYDLNKNNGF-SINGDKKVLSASMIKLLILAELMKKIS +EDKFSLSDTIMMTNFMKTGGDGVLKELNAGHFTLKELATLMIIISDNQATNILIDFL-GM +ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLLKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] serine hydrolase n=1 Tax=Acidovorax citrulli TaxID=80869 RepID=UPI000324B3E0 +------------------------------------------------------------ +----------------------------------------------------------GS +QRVQALARTLQVQKDDLKKTMEEAYDRYYAWGTNTATLAGYGGMLEKLVRGQLLTPPHQQ +MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAQAIVVATCAE +DMDEMRQAGRLFEQLGRAITR-- +>[subseq from] Beta-lactamase n=2 Tax=Gemmatirosa kalamazoonesis TaxID=861299 RepID=W0RJT0_9BACT +---VERRVAELRGTADAFVAVAWRDLGTGERL-DLHGDSVFHAASTMKVPVMIELMRRSD +RGALALDQEILLVNRSIVDGSPYAYALVGRRVAVRELIRRMIVRSSNLATNALIALA-DP +AQVTATAASLGAVRTRVRRGVEDQK-AFDKGLNNVTTASDLAALLEAIERGRAASAGACA +EMRRVLLGQELDAGSIPAGVPPGTRVAHKSGQIT-GVLHDAAIVYPRGRPPYVLVVLTRG +IP-DEKLAAAAIADVSRLVYAY- +>[subseq from] Serine hydrolase n=1 Tax=[Brevibacterium] frigoritolerans TaxID=450367 RepID=A0A4Y8U7S9_9BACI +-qTIEHDILALVETFNGRIAYKIEN-GIGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE +KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +MQ-SEEESRQVISKIGKMIYD-- +>[subseq from] Beta-lactamase n=1 Tax=Erythrobacter lutimaris TaxID=1538146 RepID=A0A395LHT4_9SPHN +--AFERQIANLADGSDGRIGVYAIDLVTGQEV-GILADQRFPMASTSKVAIAATFLAGVD +QGRWSLTSEFELPG-------------RGKYISAREHLDLMISRSCNDCTDALLYAVGGP +QAVNAWMRNAGISEFELTRDIATLVRASQIAFEDSASPRAMGQLLAGIYQGKWHSSYSRQ +VLMNAMSATVTGKRRMTSALPMSANLAHKTGTLSR-TASDIGIFYTPDGRPIAAAIYVTG +QSPSMAVE--------------- +>[subseq from] hydrolase n=1 Tax=Leptolyngbya sp. PCC 6406 TaxID=1173264 RepID=UPI0002AC8BDE +-----------------TQSTFLLDLDSGRYA-DINGGTAIAAASTIKVPILVAFLAAVD +SGRLTLDQAVTLQESSVVGGSGEMQTALGTRYTAYTVATEMMIASDNTATQLMIELLGGA +SALNQQFQSWGLRSTVLRNPLPDLEGT------NTTSPRDLVRILTLVEQGDLLQPRSRD +RLLSIMQRTYS-RDLIPAGIAEGALVFNKTGDIGT-LLGDVALVEAPNGKRYILSTLIQR +PHND-GRAAELIRRIAETVH--- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536IJ97_9CHLR +--------DSLARDI-GIVGVSATHLTTRRHI-GVREDELFPTASVIKLPLLVTMYEESL +AGRLDLTERVRYDAGTRVAGSGVLQYLDAGLPTVRDLAVLMMSVSDNTATDLLLERV-GK +GRVEAAMGRYGLRSIRIPFGIREMLMVIPA-QADRSSPRDMCRLLELLARKEILDPPSCD +AILGLMERIQS-GTRLPGLLPKGTVVAHKTGSYRR-VRNDVGVVYAPNGA-YAVAIFARE +LVRDNVDDDRALAQLSLAVWEE- +>[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. AG162 TaxID=2572910 RepID=A0A542SFR2_9BACL +---LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY +AGKFALEDKIKLRAEDLVGGAGVLQQMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT +ESIRNAMQKTEMTNSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRYLGTGKVISYDSCL +KMVAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSLLNKG +LE--QKDAANVMAQIGTLVYRVy +>[subseq from] serine hydrolase n=1 Tax=Spirosoma lacussanchae TaxID=1884249 RepID=UPI001108B7FB +---------------SARVSVAVESLADSSVSyARRADERVPSASVIKLPILLEAMERVK +AGTLDLDEIHILTDAEKVGGDGVLKTYSHRSIAYRDLLRLMMVYSDNTATNIFINEL-GM +DAINARIRAVGLPKSQLNRVMMDTLAA-RQGRDNYVTCFEMNRLLKKIYRRQVATPELCE +QMLTLLKQNED-TLTIPRLLPPGTVVAHKTGTLSY-IRADVGIVYA--RQPFLLSIFVEG +LP--TADAERTIAETARICFTYf +>[subseq from] Beta-lactamase n=2 Tax=Fusobacterium TaxID=848 RepID=R5XJ41_9FUSO +-tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGDKKVLSASMIKLLILAELMKKVS +ENKFSLSDAITVTEAMKTGGDGVLKELNSDHFTLKELATLMIIVSDNQATNILIDFL-GM +KNINLLGKELRLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQKKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILAVLTNG +MP--NFQCKQTIGKISKFVYDK- +>[subseq from] CubicO group peptidase, beta-lactamase class C family n=1 Tax=Parapedobacter composti TaxID=623281 RepID=A0A1I1KP95_9SPHI +--DLRKRIGQIMKRHKGRFAYALLDMQNGEQL-LYNAGETFHAASTMKTPVMIEVFRQAA +AGKFRMTDSITVYNESIVDRSRYSYARIGTKLTRHDLVYRMITESSNLATNILIDQV-GA +KSVMKTMKTMGANDIQVLRGVEDTK-AFEKGLNNTVTAYDLMLLFKHLAAGTAVDRASSE +AMVDILKAQRF-RSMIPARLPDDVVVAHKTGSITE-ILHDSGIVYLPDGRAYVLVLLSGG +LPDD--DARNALASISRLVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Sphingobium baderi LL03 TaxID=1114964 RepID=T0GLK2_9SPHN +------------------MGISVRDIDEGWTV-SFNGDASLPQQSVSKLWVAIAVMDAVD +RGKLKLSDPVTVRRSDLTVHQPIRPLVTKSGTTIGKLLELAMTRSANSCNDVLLWKVGGP +SAVRTMLARKGVSGVGFGPGERVLQARYLAAPYDGASPNGITLGLAMLKRGELLTPASTR +HLLSLMRASRTGPLRLRSGLRSGWTLAHKTGTGQSTGYNDVGILNSPDGHRYAVSVMIAS +TRQPIPVRMRLMGDVTRAIIR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax sp. CF316 TaxID=1144317 RepID=J0TZ42_9BURK +---LQAELVQVAAQNTAGIGVYVRDLETGIAV-SHRGMERWYLASTVKVPVALAVLQAVE +RGEFTLDTKLRVRASDYVDGAGQTNKAVGTALSVRYLLEQMVIYSDNTASDMLIGLV-GI +RAVNALVEQLVPRGFERITSLADVRRAYYAGGLNSGRLDAYADLLELLVHGKIVNPEHTR +YLLAVMERVQTGVYRVQAGLPKAARFAHKTGTQR-ARTCDSGLVTVPGRDRRVIVVACTR +GELSSARSDRALRDVGAALCQ-- +>[subseq from] DUF3471 domain-containing protein (Fragment) n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A4V1UFY2_9BACT +--DLNKKIASIFAAHEGEFAVAFKDLSTGKEL-LLNARTNFHAASTMKTPVLIETFKQAA +AGKFSIDEPILIKNESIVDGSLYHYTKVGTKLPLRDVLNRMITRSSNLATNIVIDLV-GA +TNANASMRSLGAKDIQVLRGVEDDK-AFQKGLNNTTTAYDLMLIMEAIANGKAFDQKASD +EMLKILFDQKF-NDKIKKKLPPEVKVASKSGSIT-AVSHDSGIVYLPDGRKYVLVLLSKG +VQ-SYDEVNNTLANVSRLIYDY- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3C0ZGX7_9BACT +--DLKRSIDAEFRKVEGVFGLAFFNLRTGEML-LINEREMFHAASTMKTPVMIEIFKWVK +EGRLSLGDSIEVKNESIVDGSSYQYRRIGGKATIRELMYQMITVSSNLATNILIDLV-DA +KNVSATMRSMGAVNIRVLRGVEDGQA-FRKGLNNTTDAYDQMLILRAIAEGRAVDSASSK +AMIDILFEQKF-NDLIPALLPKNVRVAHKTGSIT-GVEHDCGVVFLADGRRYVLVILSKE +LK-DVKGGKDVIARVSKMIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Pigmentiphaga aceris TaxID=1940612 RepID=A0A5C0AVG0_9BURK +--RLQASLEMLDERVHADVGVYVHDLTTGIAV-AHRAHESWYLASMVKVPVALAVMQAVD +RGEISLDTRMTLRAADYVDGAGNTNSMAPGTLSVRHLIEQMIIYSDNTASDMLIELV-GL +DAVNALVQTVIPGGMRPITTLADVRRAYYATRVNSGPLDAYGALLAQLAQGRVLTPASTD +YLLKTMRRVKTGDRRLKAGFPPATLFAHKTGTQR-ARFCDAGIVDIPSARQAVIVACVSG +-DASLTRSEQALKEVGTVI---- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI0012472D00 +----ENQIQDLIQKTPYKVHLFVKDPKTEQFLfSHQLEESFSSASIIKVPILLAVLAYTE +KHNISLHSALTITPADWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM +DFLNDYFRQIGLQETLLQRKMMDVER-LAMGIDNFTSARDMAHLFTRIYQQDLLASPYNE +LVIEILSRQRV-HEGLKRYLVDDVKLAHKTGGLDT-VDHDAGIVYSSSFD-YLIGVFITN +VT-DNDLARQLIGRLSKVVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9KZN1_9BACT +haKLEAEINRVADRLNGVLGYAIKDLSTGESF-YRNADLVFPTASSIKLAVLLELMRQDQ +EGTLSLNEKHTVRHSELPPTDPILHMLGDGTMTLRDVATFMVVLSDNGATNILIDRA-GM +DNINAEIARLGLTQTHLRRRMIDIEAARRG-DENVSTPRELMALLEKVRGGGALDAAHTK +EYSDLLGLPK--DSLFNKALPATVRIEDKPGALD-AVRCDAGIIEVPGH-PFAMSVMTTY +LG-SNDQGERAIKQIARLAYEHf +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3A0E280_9BACT +--KVQLELESIAADVQGVMGIAVEDLAGQHRF-AVNEGLQFAQASAIKIPILMEVLKQAH +EGKLKLEEMHWIEKQYQVAGSGVLGEHRTTQMSLEDLCVLMIVLSDNTATNMLIDRV-GM +DEVNRTMESLGCRHTKLRRRMMDVAAAQ-RGDENVSTPADAARIMRTLHEGQFVSREVSD +HVLAILRKDKPGD--VKAALPAGTSVAFKPGAIP-GVAAEWAIVELERR-PYIVVAMGGF +GV--KEEFKDAFREVSKTAYEFf +>[subseq from] Uncharacterized protein n=1 Tax=Peptoniphilus grossensis TaxID=1465756 RepID=A0A1U7M079_9FIRM +---LEEKIKSLINEVQGEFGVYFEDTVDGTKI-LLNENIVFSAASTIKIPLVALGLKLSE +EGKFGLNDEIEIKPENRVGGTGVLKTLNRNYPTVSDLMTLAITVSDNVATNQLVDLVGGF +DNINEFSKSLGLNDTKFQRKMLDLKSL-QEGKDNFTTAKDLGTILSLVAKDECVSKESSE +LLLKMMKMQQF-RQKLPNLIPAIVLVANKTGDLWK-VQHDVGIFILPKGERYVISVFSQK +LAED-YEGIETISKISKAAYEY- +>[subseq from] serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=UPI0004041F3B +--EWKEKIKKIISQSEGQVCVNFYDLDRKEGF-SIDGDKKVLSASMIKLLIIAELMRQVS +ENKFSLSDKITVIEVMKTGGDGILKELESNHFTIKELATLMIIVSDNEATNVLIDFL-GM +NNINQMAKNLGLKETYLGRKMMDTEA-RKNGYDNYTCANDISLLLKLIYQEKLINKEASQ +LILDILLKQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENNGGIIYLSNKT-YILVVLTSG +IS--NLKGKQTIGKISKFIYDK- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. FJAT-21352 TaxID=1581030 RepID=A0A5E8L2S9_9BACI +--TIEHDILGLVETFNGRIAYKIEN-GIGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIRELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE +KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKMIYD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A539EG41_9BACT +---MTAELQRTASSSRWRTAVYVKDLQRGYEW-AYHAEDLFPAASLIKLPIMVGVFEKIQ +RGQLSLYSKLKLRRTTRMGGSGSLKWQRDGTYTVRYLLEKLIKESDNTAMLLLLDEV-GI +GFLQQYFPQMGLVYTEINSDGLRLDSG-GVRTENYTTAREMGAVLERIYRGELVNGFASE +LMLDILKRKRA-RTRLAKHLPPGWQIAHKTGLLRR-SCHDAGIVFSPNGD-YVMVVLTGR +VD-SYPAAKELIARLGKTTYRTy +>[subseq from] Beta-lactamase class A n=1 Tax=Nostoc sp. (strain ATCC 29411 / PCC 7524) TaxID=28072 RepID=K9QV33_NOSS7 +--QLDSQIKSLMARYSLSPGMFFLDMETGEYL-DINGEKIFPAASTIKFPILVALFQEIE +AGRVRTNETLVMRRDLMTGGSGNMQQKPGTKFNLLETANRMMIISDNTATNMIIDRLGGK +NRLNERFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLAALISNEKLLGSSGYT +QVMNIMSRCKN-RSLLPVGLGKGAAIAHKTGTLGR-VLGDAGIIQTPSGKRYLAGILVAR +PFRD-ARARSFINQVSRLVYG-- +>[subseq from] Beta-lactamase n=1 Tax=Fusobacterium nucleatum subsp. animalis ATCC 51191 TaxID=997347 RepID=F9EL26_FUSNU +-tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGNKKVLSASMIKLLILAELMKKVS +ENKFSLSDAITVTEAMKTGGDGVLKELNSGHFTLKELTTLMIIVSDNQATNILIDFL-GM +ENINQLGREVDLKETFLGRKMMDIETR-KKGYDNYTCADDISLLLKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKT-YILVVLTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Beta-lactamase class A-like protein n=2 Tax=Bacillus TaxID=1386 RepID=A0A098FBC7_9BACI +-qTIEHDILALVETFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE +KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKLIYD-- +>[subseq from] serine hydrolase n=1 Tax=unclassified Acidovorax TaxID=2684926 RepID=UPI000D3346ED +---LQAELVQVAAQNTAGIGVYVRDLETGIAV-SHRGMERWYLASTVKVPVALAVLQAVE +RGEFTLDTKLRVRASDYVDGAGQTNKAVGTALSVRYLLEQMVIYSDNTASDMLIGLV-GI +RAVNALVEQLVPRGFERITSLADVRRAYYAGGLNSGRLDAYADLLELLVHGKIVNPEHTR +YLLAVMERVQTGVYRVQAGLPKAARFAHKTGTQR-ARTCDSGLVTVPGRDRRVIVVACTR +GELSSARSDRALRDVGAALCQ-- +>[subseq from] Serine hydrolase n=1 Tax=Blastocatellia bacterium TaxID=2052146 RepID=A0A3B9LUP8_9BACT +--KFSHRVEDIASHVDGVVGYAALDLTSGDRF-GHLEKDTFPTASTIKLAIVYELFKQVK +EGKVRLDETMVLDRSKAVGGSGVLSQLGTPTLSIRDYATLMVMLSDNTATNVLIDRL-GM +DAITRRMQSLGLGGTKLRRHMMDTAAARRG-DENVSSPEEIVRLLQIINQNQ-------P +DAIALLKKSKE--SHLRKGLSAGVETADKPGELE-GVRVDAGVVFAKNR-PYILCVMTTF +LK-NEADGERAIEDISRAAYEYf +>[subseq from] Uncharacterized protein n=1 Tax=Tumebacillus avium TaxID=1903704 RepID=A0A1Y0IVM2_9BACL +-----PALQNLIEAARGTYGVSIYHLESQSEF-SYQADEWFYAASIIKVPIMAAVFDQAF +KGKLSFEEKIALRAEDMVTGSGLLQNLSPGLLSIYDYTMLMIIDSDNTATNILIDRI-GT +QAIQDAMAEWGLTGSGFYNKISVIPAKIEN--FNTITPRDMTRLLKLIADGKVVSWRACA +EMVKIMKQQKY-NEGLPSLLPQQWECAHKTGWVN-GTDHDMGLLYFPHHT-FAVSVFGKN +IT-DRKDAHHLMGQIGRLLYDH- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A520Y9Q0_9SPHN +--ALGTDILERVRSFNGTSGIAVHSIDGGWET-GWQTARLFPQQSVSKLWVSLAVMDQYD +RNELDLRKRVTLDRDDLTLWSSATRASILRGRTLDQLMYDALVSSDNHANDRLLREVGGP +EAIREMIERKGLGDIRFGEGERLMQARYLDDPYDGASPLAIVRALAKLERGELLSPASTA +KLLTTMGMAKTGRLRIKSSLKPGWTWIHKTGTGQVGGLNDIGILSAPDGSSYAIAVMTIP +NST-DGSAQELMRDIGSMVIAH- +>[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus fusiformis ZC1 TaxID=714961 RepID=D7WTR3_9BACI +----EQRITTLIQESPYNVHLFIKNLTTNQLLiSHQLEASFSSASLIKVPILLALLSYIE +KNKLSLDSTLTISPTDWVDFSVISEQRLTQ-STFYELLVWMIITSDNTATNVLIDVV-GM +AYLNDYFQHIGLQDTLLQRKMMDVDR-LAKGIDNRTSARDMAHLYTCIYQQELLSPPYNK +LVIDILSRQRV-HDSLKRYLIEDVRLAHKTGGLDT-VDHDVGIFYTNAV-DYSMGVFITN +VT-DNDQARQLIGRLSKVVYDQ- +>[subseq from] Putative beta-lactamase n=1 Tax=Bosea sp. LC85 TaxID=1502851 RepID=A0A085F0Q8_9BRAD +------------------------------------------MQSVFKLPLAVAVLQSIE +AGKLRLDQEIRVKRNELALWSPMKKGFTGEEYTVTDLLTRSTGASDNSTADVLMKRIGGP +KVVTTMLSEGGIAGISVDRYEREFQPYIKGEVRDSTTPEASIAFLEGLARGNWLREPADR +LLTEILVKSPTDAQRVRAGLPTGATFAHKTGTGDNSATNDIGIVALPDGRRFAIAVYLAG +AKVDAKGREAAHAAVAKLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Nakamurella lactea TaxID=459515 RepID=UPI0006843654 +--EAEQRVRDLVRPAPGRVAVVARAVPGGQGF-SVAGDESFTSASLIKVPVLVSALQQVE +AGALSLTQRVRVDTSPRVGGSGILAGLSDVTVSIRDLLELMITISDNLATNLLIETL-SV +PTIAASIEAAGLTNTALQRRLMDLQAR-SRGLDNHTCATDMALLLEQIAVGEGLSADSYR +LAREVLARQQV-NDRLPRQLPHGWVLAHKTGELD-GVRHDAGFVTVDSSPVLVIAVLTEG +FGAYGAAAADLVADVGRIVYS-- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A2A4BLA4_9BACI +-qTIEHDILALVETFNGRIAYKIEN-GIGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE +KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKLIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8A5Y5_9BACT +--KFEQRLQQISSRVDGVVGYSVLDLTSGDRI-AHLERETFPTASTIKLAIVYELFRQAA +EGRIRLDDTIALDRAKAVGGTGVLFQLGTPTLSVRDYATLMVIVSDNTATNVLIDRL-GM +QNISARMQSLGLGATKLRRHMMDTAAARRG-DENVSTPDEIVRLLQAIEKDE---PDASA +----LLKKPK--ESRLRRALPPGVEAADKPGELD-GVRVDAGIVFAKNR-PYALCVMAAF +LT-SEVEGERAIEEMSRAAYDYf +>[subseq from] Class A beta-lactamase n=2 Tax=unclassified Muribaculaceae TaxID=2006847 RepID=A0A4Q0IAL4_9BACT +--DMETELKTYVHDKDARIGVAVI-INGMDTV-SVNGKRDFPMLSVYKFPQAIAVADYCS +RHNILLTDSIRISASEMKPWSPMREKYGRKDLPLSEILAYSVQQSDNNACDVLFRLIGGP +QVADSLMKKLGYDEIRILNTEDEMHADPYLCYANRATPLQMAALFDRLYRQEMRHSPVLE +AVGAMMMQCVTGNNRLPLPLPTNAMIGHKTGTGDVNGVNDAGYVFLPNKQGYAIAVFIAD +SGYGMTETEKMIADISEIAFK-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonas glacialis TaxID=658225 RepID=A0A502FFC7_9SPHN +--DLLNAVQALGSGFPGQVGIAVRDVTEGWIV-GYNADRLLPQQSVSKLWVAIAVMDAVD +RSTLKLSDIVTVRRSDLTVHQPIRPLVGIDGTTIAALLQGAMTRSDNTCNDVLLWKIGGP +PAIRRMLMQKGIAGVGFGPGERLLQARYLAAPYDGASANGVTLGLARLQRGEVLSNSSTL +HLLTLMAASKTGPLRLKSGLRSGWTFAHKTGTGQSTGYNDVGLLKSPDGHSYAVAVMIAS +TRRPIPARMQFMGNVTRALIR-- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium GWA2_66_18 TaxID=1797926 RepID=A0A1F9R057_9BACT +--KMTAALDKTAVHYPGRVSICMRDLRTGKTW-MYHPDDLFPAASLIKVPILIAAFYKMK +DGQLSLEEKLPITRRNRVGGSGSLKWRPDGTLAVRELLIHMINESDNTATKMVLERL-GL +GYVQQQFPRMGLLYTGIYEEGMSIKGG-RVAHENYTTAREMTMLLEKIYKGEAVDKPSSD +LMMEILKKPKAVASRLAKGMPTGWEIAHKTGLLRQ-ACHDSAIFLTPNGD-YSLTVLTGQ +NQ-SYSQAKTFITKLAHVTFANy +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetales bacterium 71-10 TaxID=1895807 RepID=A0A1U7GIU8_9BACT +-----------------------YDFATGATH-LIRADEPIHPASTMKVPVMLEAYRLAE +AGGLRLDDEVEVKNTSLVDGSPYSYKRVGGKATVRELVFLMITESSNLATNILVEKV-GA +KAVTDFMAKLGAPDLKVLRGVEDDK-AVKAGMNNVGTARGTMTILKRLAEGTAVSKAADA +AMMDVLRAQKF-NNGIPAGLPEGTPVAHKTGSFA-GVYHDAAVVEPAGRAPFVLVVMTRH +VPDDDPKARELAAEIARIAYRH- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013B028F5 +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTRR----------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Fusobacterium nucleatum CTI-1 TaxID=1204474 RepID=U7TE06_FUSNU +-tEWKKEIEKIISQVEGSVCINFYDLAKNTGF-SIDGDKKVLSASMIKLLILAELVKKVS +ENKFSLSDAITVTEAMKTGGDGVLKELNSEHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINQLGKELRLKETFLGRKMMDIEAR-KNGYDNYTCADDISSLLKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLLSDIKIAHKCGDLDN-LENDGGIIWLGNKA-YILVVLTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium nucleatum subsp. animalis F0419 TaxID=999414 RepID=H1HH47_FUSNU +-tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGDKKVLSASMIKLLILAELMKKVF +ENKFSLSDAITVTEAMKTGGDGVLKELNSEHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINQLGRELDLKETFLGRKMMDIEAR-KKGYDNYTCADDISLHLKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILVVLTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Uncharacterized protein n=1 Tax=Erythrobacter flavus TaxID=192812 RepID=A0A3T1CJB1_9SPHN +-----------------------RDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD +AGRLDLSEMVAIRTADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA +EAVQDFLDTHGLASIRFGIDERSKQSSYLADPIDGAPPVALVEALARLQRGELLSAGSTG +LLLGTLARTKSGPQRLKAGAPEDWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR +TREPTPVRMEMMQQVVRAVAR-- +>[subseq from] Class A beta-lactamase n=2 Tax=Vibrio TaxID=662 RepID=A0A2K1CLW1_9VIBR +--SLESTIATLEEETSSRIGVSVWDTHSNERW-DYRGYERFPILGTAKVFVCAAMLDAIE +RKTLNKDATITIKPEELSSYSPATQHWVEKPIDLTTLCEAATLEGDNTAANVIMRELGGP +QTTVLFLRSIKDTKTYLTEYFPTDSSL----RGNSSTPNTMVLNLRNILEGDKLNYGARE +QLKTWMKNIKRSKSKVFPTIPEGWSIAERRGFARD-SRAELFVIWREGYQPVYVGIYIKD +YDLSIQASEQLLTQVAQLILREy +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. FJAT-22090 TaxID=1581038 RepID=A0A0M4G5W7_9BACI +--SLQQKIESYIENIDATFGIYIKHLGTNEEV-NIQENQLFQMASVCKVPILATLYEKVY +KGEIDLQERIKLVEEDYVPGSGVFQAMDYGVPTIKDLATMMIIVSDNLATDKVLSIVGGA +DRVQDRMHQLGLSNIYTKHTIWELLSFQDSTENNVSSAKDMSLLLEKIALGEFVSAECSS +DIREILFKQHF-QQRIGGLLPRNKKVANKTGSLGT-MFNDAGIVYLPDKGEFVITVYSVG +SSLE-YKGDEPIARIAELAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Rufibacter sp. R-22-1c-1 TaxID=2487040 RepID=A0A3M9MCQ7_9BACT +---LREEVVAELGKQKGTFAVAFKDLKTGQEL-LINEHESFHAASTMKTPVLIEAYKQAT +QGKFALTDSVLVKNESIVDGSPFSYTQLGQKRPLTELLYKMIIQSSNLATNIVIEKL-DA +KKVTQTMRELGAKDIQVLRGVEDTK-AYRQGLNNTTTAYDLMVLFEKMGQGKTVSKAASQ +EMINVLLDQKF-KDVIPAKLPTDVKVAHKTGWIT-GVRHDSGIVFLPDGRQYVLVLLSKG +LE-DEKAGIAAMANVSEMIYRH- +>[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E311E68 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLDNMGDHVTRLDRW---------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. Soil745 TaxID=1736396 RepID=UPI00070EF482 +-qTIEHDILALVETFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE +KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVVHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKMIYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Eremiobacteraeota bacterium TaxID=2052317 RepID=A0A2W5XBI9_9BACT +--SLQEALADRIRRVPGTAGVYVRTMQSGPALfTYNTEESFPAASTIKMLIMLTAFHREE +TAPGSLQAPVRLRSSDFVGGSPYLARASAGEYTVAQLVTPMITLSDNSAANALITHF-GF +DAINASARRAGLSNTYLRRHFLDYS-AIVHHHENVTTAGDMGRLLFSLERGAVAHPMFCR +RMVAIMLHQTD-RDKIPAGLPAGTPVANKTGEVD-GVRNDIAIVDPFGDSPFVLTVFTKN +LS-SYELARRAIAAIASDVF--- +>[subseq from] Class A beta-lactamase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A2A8FSL1_9BACI +-qTIEHDILALVETFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLM-GF +EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE +KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKMIYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E2ALY4_9CHLR +------NIEKAIFRVNATVGIAAKHLATGREI-LQNANDTFYTASTFKVPLIVALFRLVD +QGKIDPSERIKFSDSMRVPGSSILKVMGAGLPTIHDLAMLMIIVSDNTATDLIFDRV-GK +EFLNSTITEMGLSNTRIPMTTRELLYGFQEDKSDVSSPSDMSKVLELIHSGGFLSDQSSE +AVLNILLRQQL-NNVIPLLLPSGTKSAHKTGSYH-GVRCDVGIVYGESG-PYTVAIMAKG +ASGISLETDLSLARVSRAIYDEf +>[subseq from] Uncharacterized protein n=2 Tax=Bacteria TaxID=2 RepID=K2EBT5_9BACT +--NLTKRLKNLASKYSLEPGIFIWDISSGQYV-NINADKEYPTASIIKIPILFQLYKRAE +MGLINLNEKMSLQEYYITGGSGFLQKPVGTDLSVYNLAQIMIQESDNTATNMLLSAVGGT +NGLNRVLRSWGFSQTHMSDLLPDLYGT------NVSTPKDIGTMLYNIDNPDFLTLKSRA +NIVNIMSHVKN-RFLIQAGLPSNAEFIHKSGDIGS-MLGDAGIVMLPDGRKYVIVIMVKR +PW-NLYSAKEFIIKASEITYNSf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A4Q6F6B6_9PROT +------QIASLAEASRGRIGVAAIDLANGRTI-EVLGNQRFPMASTSKIAIAATFLEGVD +KGRWTLDQQFPLMVPQASKLSTKTAPVKPGRMSAREMIERMITRSDNQATDGLLAVVGGP +QSVNSWVRRAGIDGFSLDRDIATLVRATYIDKRDSATPLAMAQMLSGLHQGKWLSAQSRQ +VLIGAMERCITGKNRIPGKMPSNVLVAHKTGSLYN------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Melittangium boletus DSM 14713 TaxID=1294270 RepID=A0A250IRM9_9DELT +--------ERIAQVKGASVAVAYRDLGDPKDSlDLEADRSVHAASTMKVAVMLEFFRQVD +AGSLSLDMAPVLTNQSIVDGSPFAHERMGQPVPVRELVERMITRSSNLATNAVIARV-DA +KRVTKTLRALGARRMTVLRGVEDGK-AYAKGLNNTTTARDMAVLLSAIERGMAASPASTQ +AMRTILLAQEL-NQEIPAGLPAGTPVAHKTGQIS-GVLHDAAIVYPPGRKPYVLVVLTSG +IP-DEQVARALIVDVSRMVYAH- +>[subseq from] serine hydrolase n=1 Tax=Tuberibacillus calidus TaxID=340097 RepID=UPI00041FF742 +-eKLTRCIEKWINEAGGTWGIVLEDLNEGVRW-EHNEDRLFYAASMIKLPIMAAVFAAAS +RGDFRLTDSLTMKKDDIVGGSGVLQHLSPELLPIYDLVTLMIIQSDNTATNMLIDLV-GF +QEIRNAMQNLGMEDSTCFTKLMTVPVERPG--RNMVTARDLNRLLKKLATGQFVSLYACE +HMIDIMKKQQF-RDCLPSLLPDDWEFANKTGWVT-GIRHDGGILYVGERA-LAITVLSES +V--DDRQAKATMGKIGRAAYEY- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9DQ62_9BACT +-------------ASGAEVAVALRTLDGRDEL-FIAADQSFHAASTMKIPVMIELFTQVQ +AGKVRLDEPLAVKNESIVDGSVYQYKAVGQTMTLGRLCEAMITVSSNLATNLLIDKL-GV +ENIRRTVHSLHADGMQVRRGVEDGKA-FAQGINNTTTARALLILLEAIAKSEAVDPASSH +AMVEILKRQKF-NEAIPAGLPAGTPVAHKTGEITK-IHHDAAIVYGPRA--YVLVILVRG +LAE-KERSAALMAEITKLVHQ-- +>[subseq from] serine hydrolase n=1 Tax=Bryobacter aggregatus TaxID=360054 RepID=UPI0004E1C564 +--KMHDRIVAYDARMDGALGVAIIDLTTGTQW-SYHGKLVFPTASAIKVPILMEIFRLRE +LGQLHFNEKVTLQPAEAVGGSGVLQERLRNGLSVEEIVREMIASSDNTATNWCIRRV-GM +AGVNHTMAQMGYQGTRLQRIMIDQAAA-TRNEENVSTPEDMADMLRVIYEGKAVNAKASA +EMIAMLKLVKA---GMRRAIPPAIEVASKPGELV-GVRTETGIVYLKGR-PFVLAVMGTY +LNES----DSPIEAVTKIVFDCf +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. OL1 TaxID=2517243 RepID=A0A4Q9TZ05_9BACI +----EQRITTLIQESPYNIHLFIKNLTTNQLLiSHQLETSFSSASLIKVPILLALLSYIE +KNKLSLNSTLTISPTDWVDFSVISEQRLTQ-STFYELLVWMIITSDNTATNVLIDVV-GM +EYLNDYFQHIGLQDTLLQRKMMDVER-LAKGIDNRTSARDMAHLYTRIYQQELLTPTYNK +LVINILSRQRI-HDSLKRYLVEDVRLAHKTGGLNT-VDHDVGIFYTNAV-DYSMGVFITN +VT-DNDQARQLIGRLSKVVYDQ- +>[subseq from] serine hydrolase n=2 Tax=Enterobacterales TaxID=91347 RepID=UPI0011AE1BC9 +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPTR------------------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0011583522 +------------------------------------------------------------ +-------------------------------------------------ANLLLTTIGEP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase class A n=1 Tax=Lysinibacillus sp. YR326 TaxID=1855296 RepID=A0A4R7U981_9BACI +----KQTITQILQKAPYKVHMFVKDCKTEHFYiSEKIEDTFSSASLIKVPILLAVLNYVE +INNLSLEQEIKIAPEEWVDFSVISEQRLEL-STIYELLVWMIITSDNTATNVLMDFL-GM +DTLNQYFREIGLLQTTVQRKMMDFER-LANGFDNTTSARDMALLFSRIYRRDLLSSAFSD +LTINILSRQRV-HESLKRYLVDEVKLAHKTGGLDT-VDHDVGIVYSSSGD-YLIGVFITE +VTN-NDHARQLIGRISKVVYDY- +>[subseq from] Imipenem-hydrolyzing beta-lactamase n=2 Tax=Planctomycetes bacterium I41 TaxID=2528024 RepID=A0A517U393_9BACT +-rQMQARLQAIADGVDGTFGLVVADLAGQHRF-EVNADRQFTQASCIKTPILLEVLKQAH +EGKLQLADRRWVEKQDKTGGSGILAELGDRTLSIEDLCVLMIVMSDNTATNMLIDQI-GM +ENVTATMALLGCEQTVLRRRMMDAAAA-ARGEENLSTPADAARILRLLHEGTFVNREVSN +HALSILRKLKSG--AIRSTVPQSVSVAFKPGELP-GLLTEWALVELPER-PYIVVVMGTY +NPSTDDDLDAAMKQVGKEAYKFf +>[subseq from] Serine hydrolase n=1 Tax=Aureibaculum marinum TaxID=2487930 RepID=A0A3N4NIW5_9FLAO +-eNLEHTIRTQIDSINGTVAVAYYNLSDPKDSlFINVDENFHAASTMKVPVMIELFKQAN +EGKLNVNDSILLKNESIVDGSIYSYKHIGTKVAIKDLIHSMITVSSNLATNVLIELV-NA +KNVTATMRNLGAKNINVLRGVEDIK-AYNKGLSNTTTARDLMIIMKAIAKNKAGSKADSK +AMIDILKDQQF-KSVIPKHLPNSVTVAHKTGSIT-GVHHDAGIVYLPDGRSYVIVLLSKE +LK-DFEKGTEQLAKISKTIYNY- +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Calothrix parasitica NIES-267 TaxID=1973488 RepID=A0A1Z4LIM0_9CYAN +--QLYSQVKSLMSRYSLDPGMFFLDLETGDYL-DINGEKAFPAASTIKLPLLVALFEEVD +AGRVKLNETVVMRRDLMTGGSGTMRKRPGTKFGLLETVTKMITISDNTATNMVIDRLGGK +ARLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLARVGALISNNLILSSSSRA +KVLDIMHRVRN-KAYLGSGIGKNAKFANKTGTLGI-VLGDTGIVTMPNGKRYLAGMIVRR +PFRD-RRAKSFIKQVSRIVYGH- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. BN140078 TaxID=2607653 RepID=A0A5B2VRL5_9BACT +--SLQQQIADTLAQHAGVFAVAFKDLASGQEL-LINAHESFHAASTMKVPVMVEVFKQAK +AGKFSLSDSVLIKNESIVDSSSFQYTHIGERWPLSSLVYDMIIMSSNLATNIIMEMV-TG +RQVTQTMRQMGAKDIQVLRGVEDSK-AFEKGVNNTTTAYDLMLIFTAIAEAKTIDTPAAN +QMIKILLDQKF-NDIIPARLPQGVTVAHKTGEIT-GVRHDAGIVFLPDGRKYVLVLLSKQ +LQ-DTAGGVQAMAAVSEMIYK-- +>[subseq from] Uncharacterized protein n=1 Tax=Fictibacillus phosphorivorans TaxID=1221500 RepID=A0A163R3P0_9BACI +---NEQALLTLISSGEGNYGVSIYHFETKETF-EFQSDELFYSASIIKVPIMAAVFAHAM +EGKCSLSDQIRVREEDIVPGDGIIKHLSSNIWTIQDLIILMIIESDNTATNILIDRV-GL +DQINSYMKEWGFGQSHLHHKLQ-INAQREPGKMNVVTAYEMNEFLKKIAAGSVLSLNSCK +KMISIMKQQKM-NDLLPSLLPPNWEFAHKTGYVP-GIEHNVGLFYMPGQ-TYAISVLSNN +VP-NRSEPRRIMGEIGKLLYK-- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Eisenbacteria bacterium TaxID=2212470 RepID=A0A538STU8_9BACT +---LEGGIRAVVAKSHGVWGISVRHVERHESA-GVRENERFNMASVFKVPILVELFHQAS +QGKIALDERVEWKDPGRYFGSGVLQARPGLNPTIHDLATLMIIVSDNAATDQLLARV-GK +ANVNARLRALGLTKTSVDAGTREHTLQALRDCHNCSTPSEMSQLFEKIVSGLAGDSVGTN +DMLGILSKQQF-NQRLPRLLPVGIRVAHKTGTVTNPVVNDAGIIYLPNGEHVVVTAFSHG +TDKAFNDAEDTIAEIGKTVFDYy +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus fortis TaxID=2126352 RepID=A0A2P7UPH8_9BACL +---LFAQISSLIKDAGGEWGIFFEDLQTGETL-SFNEDQRFYAASVIKVPIMTAVFAEAY +AGKFALEDKIKLRAEELVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT +ESIRNTMQKTEMSNSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL +KMVDILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG +LE--QKDAAIFMAQIGNLVYHVy +>[subseq from] serine hydrolase n=1 Tax=Comamonadaceae bacterium ALPHA2B TaxID=2502232 RepID=UPI0010F850C3 +------------------------------------------------------------ +------------------------------------------------------------ +ARVRKVSQLLDVPVSRFRMPLEDAYTAYYASGVNSGRLDAYGELLALLVEGRALGRPMTD +YLLQVMERTATGTRRIKAGLPPDARFAHKTGTQRR-RICDAGLITTPRRAPVLVVACVRG +D-LSLERSESALQQVGAALC--- +>[subseq from] Serine hydrolase n=2 Tax=Acidovorax sp. Root219 TaxID=1736493 RepID=A0A0Q8T8F7_9BURK +---LQAELTQVAAQNTAGIGVYVRDLESGIAV-SHRGQERWYLASTVKIPVALAVLQAVE +RGDFTLDTRLRVRAADYVDGAGHTNAKPVGALSIRYLLEQMVIYSDNTASDMLIGLV-GI +RAVNALVEQLVPRGFERITSLADVRRAYYAGGLNSGRLDAYADLLELLVNGKVLHGAHTR +YLLGVMERVQTGVHRVQAGLPKTARFAHKTGTQR-ARTCDSGLVTVPGRDQRVIVVACTR +GELSSARSDRALRDVGAALC--- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sp. AR18-8 TaxID=1889781 RepID=UPI000826AC51 +----EQRITTLIQESPYNVHLFIKNLTTNQLLiSHQLETSFSSASLIKVPILLALLSYIE +KNKLSLNSTLTISPTDWVDFSVISEQRLTQ-STFYDLLLWMIITSDNTATNVLIDVV-GM +EYLNDYFQHIGLQDTLLQRKMMDVER-LAKGIDNRTSARDMVHLYTRIYQQELLTPTYNK +LVIDILSRQRI-HDSLKRYLVEDVRLAHKTGGLDT-VDHDVGIFYTNAV-DYSMGVFITN +VT-DNDQARQLIGRLSKVVYDQ- +>[subseq from] Uncharacterized protein n=1 Tax=Rhodonellum psychrophilum GCM71 = DSM 17998 TaxID=1123057 RepID=U5BW92_9BACT +---------------DKGLEVSLLQQPTGEILfSMNAEKSVPSASIIKIPILMEFFRQIE +SKTLHLDQMYALEAKDKVGGAGELQNLEENSHSLEFLAREMIRISDNTATNVLIGLV-GM +ENVNLLMEELGLKTTRLNRYMMDFE-AIEAGKQNITSPAEINKLLSIILSGVELSTSSRE +SMLNMLLACAD-KSTIPGKLPEGTRVAHKTGTLSY-VRGDAGIIL--NQKPIILSIFVEN +FE-TLEQADEIIANIANLAFEAy +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. Leaf13 TaxID=1736211 RepID=A0A0Q6GXA9_9BACI +-qTIEHEILALVETFDGRIAYKIEN-ADGDTI-SYHDDESFQSASLIKIPMIIEGYRQSE +EKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMTLL-GH +DEINQCIKELGLKNTILGRRMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE +KILRAFDNQQL-RDKLPSLMGKGVKVASKTGAIR-GVAHDCAIIRSEFQT--VYAVVLTE +DMKSEDESRQVISKIGKLIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A3D4YMK2_9BACT +--------ARIAVEPGVQVGLAYIDLASGDTL-FLNADSSFHAASTMKVPVMVELFRRAN +TGSFRMNQGLLLVNQSIVDGSLYAYHRIGERVRVDTLLRLMITRSSNFATNTLITLV-GA +DAVTRTMRSLGAERIQVLRGVEDGK-AFEKGLNNTTTARDLGIILRAIEEGRAASPTATR +EMLGILMAQEF-NEKIPAGLPPGTRVAHKTGEIT-AVSHDAAIVYPAGRKPYVLVVLTRG +IA-DGVKSSKLIADISAIVYAH- +>[subseq from] Class A beta-lactamase n=1 Tax=Muribaculum intestinale TaxID=1796646 RepID=A0A4S2FIH8_9BACT +--HIEERLATYIAAQDARIGVAVI-IDGRDTI-SVNGNRDFPMLSVYKFPQAMAVADYCM +KNGVGLSDTISIRGDEMKEWSPMRDRYGVGDLPLSELLEYSLRDSDNNACDILFRLIGGT +HVADSLMKAMDFDDIVIASTEDEMHRDIYLCYQNRSTPIAMAGLFDRFYRQEMRHSPLHE +AIGRIMMTCTTGNRRLPAPLPTNAVIGHKTGTGDVNGVNDAGYVFLPDGRGYAVAVFIAD +SACGMEETERMIADISDIIFQ-- +>[subseq from] Serine hydrolase n=2 Tax=Muribaculaceae TaxID=2005473 RepID=A0A3N2K939_9BACT +--HIEERLATYIAAQDARIGVAVI-IDGRDTI-SVNGNRDFPMLSVYKFPQAMAVADYCM +KNGVGLSDTISIRGDEMKEWSPMRDRYGVGDLPLSELLEYSLRDSDNNACDILFRLIGGT +HVADSLMKAMDFDDIVIASTEDEMHRDIYLCYQNRSTPIAMAGLFDRFYRQEMRHSPLHE +AIGRIMMTCTTGNRRLPAPLPTNAVIGHKTGTGDVNGVNDAGYVFLPDGRGYAVAVFIAD +SACGMEETERMIADISDIIFQ-- +>[subseq from] Uncharacterized protein n=3 Tax=Fusobacterium TaxID=848 RepID=X7SCK9_FUSNU +-tEWKKEIEKIISQVDGKVCINFYDLNKNNGF-SINGNEKVLSASMIKLLILAELMKKNS +ENKFSLSNTIMIENSMKTGGDGILKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLKESFLGRKMMDTEA-KKNGYDNYTCADDISLLFKLIYQEKLINKETSQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] serine hydrolase n=1 Tax=Pseudoflavitalea sp. X16 TaxID=2716334 RepID=UPI00141F9E46 +--QLKQAITSTLAQSEGQYAVAFKDLGPGTAL-EVNGDTSFHAASTMKTPILIEVYKQAA +AGKLSLSDSILVKNESIVDSSTYSYTRIGTKRTLYELVYDMIIMSSNLATNIVIEYV-DA +KKVTQTMRDLGARDIQVLRGVEDSK-AYQKKLNNTSTAHDLMVIFDKIATGQAVDSAADQ +AMINILLDQKF-NEIIPAKLPKDVKVAHKTGNIT-GVQHDSGIVFLPDGRKYVLVILSKG +IK-DEKAAIENMARVSEMIYQY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacter cloacae TaxID=550 RepID=Q6WWY1_ENTCL +-----EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD +AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNCAGNLLLATVGGP +AGLTAFLRQIGDNVTRLDRW---------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Omnitrophica bacterium TaxID=2035772 RepID=A0A3A4K107_9BACT +-eTLRQKLANEISQFKGEAGIVVKDLQTNRVI-YHNKDKLFPSASLAKIPIMAACFLAAE +EGRLKLVRQVALKDSDKLTGSGILKDTRHGAFTVEELIGLMIYDSDNTATNILTNMV-GI +DYLNNSFKTFGLKNTELSRRIADYKSR-DAGFENYTTVEDMALILEKIYRRVLVNKDISE +KCIKLLKLQRI-SDRLSKYLPVETLVAHKTGLER-GICHDVGLVFTSEGD-FLICVLTKH +SNSNSAPSKEFIAKLALYAYAYf +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. FJAT-20673 TaxID=1830326 RepID=UPI0007BECFE7 +-qTIEHDILALVETFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QRKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE +KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKLIYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A351I130_9BACT +--KMTAALDKTAVHYPGRVSICMRDLRTGKTW-MYHPDDLFPAASLIKVPILIAAFYKMK +DGQLSLEEKLPITRRNRVGGSGSLKWRPDGTLAVRELLIHMINESDNTATKMVLERL-GL +GYVQQQFPRMGLLYTGIYEEGMSIKGG-RVAHENYTTAREMTMLLEKIYKGEAVDKPSSD +LMMEILKKPKAVASRLAKGMPTGWEIAHKTGLLRQ-ACHDSAIFLTPNGD-YSLTVLTGQ +NQ-SYSQAKTFITKLAHVTFANy +>[subseq from] serine hydrolase n=1 Tax=Cyclobacterium sp. GBPx2 TaxID=2716263 RepID=UPI001409429F +---AQKDWQDFMKQFPDHLDISLLQDETGEPLfQQHAGKRIPSASIIKIPILISLMEKVD +EEHMHLDSLYTLQASDKVGGAGELQHLPEGSITFRYLAEEMIRISDNTATNILIRTI-EM +DYIQHWLREYGYEDTQLNRIMMDFK-AIEEGRQNYTSPQEINDILIKLWNGAWLNENSRA +EIMHWLKGCAD-NSTIPSQLPAGTVVAHKTGTLDY-VRGDAGIILG--DKPLILSVFVEK +FD-SMEEAESAIGQIALKAFRDf +>[subseq from] Serine hydrolase n=1 Tax=Runella sp. TaxID=1960881 RepID=A0A3C0UVJ8_9BACT +--SLKETIEVRLKTVEGEFGVAFKDLQTQETL-FINDHENFHAASTMKTPVMIEVFKQAK +AKKFKLTDSILVKNESIVDGSPFKYRQIGKKMTIYDLTYQMIIVSSNLATNILIDLV-DA +KNANTTMRQLGAQDIQVLRGVEDTK-AFQKGLNNSVTAYDLMLIFEKIALKKVVNKKACD +VMIHILFDQKF-NEIIPAQLPTNVKVAHKTGSIT-GVQHDSGIVSLPDGRKYVLVLLSKK +LTN-PKEGVKVLADISRLIYE-- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax avenae (strain ATCC 19860 / DSM 7227 / JCM 20985 / NCPPB 1011) TaxID=643561 RepID=F0Q209_ACIAP +------------------------------------------------------------ +----------------------------------------------------------GP +QRVQALARSLHVRKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ +MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAHAIVVATCAE +GMDEMRQAGRLFEQIGRAITR-- +>[subseq from] serine hydrolase n=1 Tax=Spirosoma agri TaxID=1987381 RepID=UPI0013DCA41E +---LSDSLAAYVKQLPTRVSIATRSLTDSRKSfYYRADERVPSASVIKLPIMIEIMERVR +AGLLDLDKMHSLLDSEKTGGDGVLKTYPHQRVSYRDMLRLMLIQSDNTATNIFINEL-GR +DAINRRIRQLGLTKTQLNRVMMDTLAA-RQGRENYVTAGEMNVLLEKIYRKQVATPNLCD +QMIDILKQNED-TVTIPRLLPKGTVVAHKTGTLPY-VRGDAAIVYARSEEPFLLSVFVEG +VS--QFEAERIIGDVALVCHSYf +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=W1I967_9BACT +---ISDSISKIASEYPGEIGVAVI-INNQDTV-TVNNKSIYPMMSVFKVHQALALCNDFD +KKGISLDTLVKINREKLDPWSPMMKDYSTSVLTVRDLLRYTLIQSDNNASNIMFKNILNT +AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAILMNRLFTESLISNEKQN +FIKNTLTECKTGVDRIVAPLKDGVVIAHKTGSGYNGAHNDVAFIRLPNNKYYTLAVFVKD +FKGNEKQAAKIIARISGTVYS-- +>[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax konjaci TaxID=32040 RepID=A0A1I1UN45_9BURK +---LERALAQAEASSGVRIGVHVRDLETGASA-SLHATEPWYLASSVKVPVAIAVLRGVE +RGDFTLDTPLTLRAADYVDGAGATNSRPVGALTVRYLLEQMIVYSDNTASDMLIGLV-GI +GTVNAVVQSLVPAGIGRITTLADVRRTYYAGGLNSGRLDAYADLLEALVAGRALDARHTA +YLLSVMERVKTGTQRIKAGLPAGARFAHKTGTQR-ARTCDSGLITVPARERRVLVVACTR +GEPSTARSDRALRQVGIALC--- +>[subseq from] Beta-lactamase n=1 Tax=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) TaxID=485917 RepID=C6XYR5_PEDHD +--ELSRRIKAETNKYNADFAVAYKDLGTGETF-LMNAKTNFHAASTMKTPVMAEVFKQAA +KGKFAISDSVVVYNQKSIAGGGLYYHKIGKKMSIENLLLLMITRSSNLATNILIDKV-GA +KNVNKTMRSIGAHDIQVLRGVEDGK-AFEKGMNNTVTAYDLMLLFEKIAKGDMVNKKASE +AMVDILMQQTF-RGIIPARLPKEVKVANKTGSITK-VLNDSGIVYLPDGREYVLVLLSRG +MEE--EAAKKTLSSISEYIYNY- +>[subseq from] Serine hydrolase n=1 Tax=Acidovorax sp. Leaf160 TaxID=1736280 RepID=A0A0Q5LHH0_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +RRVQALARALDVPQAQLQKTMDEAYARFYRSGDNTATLVAYGGLLESLVRGKLVNAEHQQ +LLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQHQ-RACHMGVIDPQDGQRAIVVATCAE +GLDEQKQAGRAFEALGRAITQ-- +>[subseq from] Beta-lactamase CARB-6 n=1 Tax=Verrucomicrobia bacterium ADurb.Bin118 TaxID=1852928 RepID=A0A1V6DM14_9BACT +hqKTEIRLREIAARTRGALGFVALDLTSGERF-ALNETLTFPQASAIKIAILMEVYKQAE +EGKFKLTDARRIARADKVGGSGILKHLGDDTLSLADLCVLMIVLSDNTATNLLIDLV-GL +ENINRTLDALGLPHTRVRRRMLDTAASWRGD-ENVSTPAEAARIMEILFKGEFQNRATCE +AILALLRQTQG--GSIQAALPAHIPVAFKPGGIA-GVTTEWAIVELPGR-PYVLVVMENY +GLE--TDADTAIKELAVVVHEHf +>[subseq from] serine hydrolase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=UPI00076B9CFC +------------------------------------------------------------ +--------------------------------------------------SALLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] serine hydrolase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI000D15C6CE +--PLERALARVEADSGVRIGVHVRDLDTGASA-SLHGTEPWYLASSVKVPVAIAVLRGVE +RGDFTLETPLTLRAADYVDGAGPTNSRPVGTLTVRYLLEQMIIYSDNTATDMLIGLV-GI +GTVNAVVQSLVPRGFGRITSLADVRRTYYATGLNSGHLDAYADLLQALVEGRALDARHTA +YLLSVMERVKTGTQRIKAGLPPGARFAHKTGTQR-ARTCDSGLVTVPRSGPRLLVVACTR +GEPSTARSDRALRQVGIALC--- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. FJAT-22058 TaxID=1581037 RepID=A0A0M1NPZ2_9BACI +--TIEHDILGLVETFKGRIAYKIEN-GIGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIRELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE +KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGEMIYD-- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacteraceae bacterium AT-5844 TaxID=1054213 RepID=H0A7X3_9PROT +--SAKAEIARIAAFAEGETGVAALHMETGEAI-GFGEHGRYPPGSSIKMALVLCIFAMVD +RGELSLDDMIEVDDVEMTSSGPLGGEFVHAGLSLINLIEVTITRSDNTATDVLFRLAGGP +AAVQAWLRDIGIDDFDVTLSMREALCDYQLSVRDHCTPLAMLELLRRLYQLDGVSARTRE +LLLPIMQRTPS-FNRIRARLPKGVVGGTKPGSGS-GTCSDVGFITLPGRGTFAISVQVKA +SPRSMAEREVVVADITRLIYDYf +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. YS11 TaxID=2072025 RepID=A0A2I7Z1Y8_9BACI +----EQRITTLIQESPYNVHLFIKNLTTNQLLiSHQLETSFSSASLIKVPILLALLSYIE +KNKLSLNSTLTISPTDWVDFSVISEQRLTQ-STFYDLLLWMIITSDNTATNVLIDVV-GM +EYLNVYFQHIGLQDTLLQRKMMDVER-LAKGIDNRTSARDMAHLYTQIYQQELLSPPYNK +LVIDILSRQRI-HDSLKRYLVEDVRLAHKTGGLDT-VDHDVGIFYTNAV-DYSMGVFITN +VT-DNDQARQLIGRLSKVVYDQ- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Peptoniphilus lacrimalis TaxID=33031 RepID=A0A379C2D1_9FIRM +--KIKKHIEKIISESSGNICLSFYDLDDEEGF-SINEDKKVRSASMIKLLIMAEIMNQSK +NGKISLDTKIKVGKKDKVGGSGILKEFDCEHFSIKELMTLMIIVSDNQATNILIDLV-GM +DNINLMGKRLNLKSSSLQRKMMDIK-ALEKGRDNYISAIDVKVILEKIYRKTLVDEKSSE +LMLDILLRQHE-RQRLGRFLDEEVKIASKTGDLDK-LENDGGIFFLENKN-YILVVLIDD +AV-TNAMAQETIGKISKYIYDE- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus asahii TaxID=228899 RepID=A0A398AY73_9BACI +-qSIEPKILELIETFDGRIAYKIEN-DRGESI-SYHEHEAFQSASLIKIPMIIEGYRQAE +NKDIYLNQPLTIPRNEVTRGSGVLHTLSDKVLTVEDLLTLMITISDNTSTNMMMTLL-TF +EKINQCIQELGLENTVLQRRMFDFKA-LKEGRDNTMSAADTVLCLKAIHTGDFLTKASQE +RILDIFEQQQF-KERLPAMMGKGVKVGNKTGSLR-GVMHDAAIIRSETET--VCAAVLTE +DMASEEESRQIISKIGKLIYDE- +>[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc sp. NIES-3756 TaxID=1751286 RepID=UPI00082E1D11 +---LDFRIKQLMNCYSLSPGMFFLDMETGEYL-DINGEKTFAAASTIKFPILIALFQEID +AGRINPNETLLMRRDLMTGGSGTMQYKAGTKFSLMETASKMMIISDNTATNMIIDRLGGK +NRLNQKFHSWGLQNTVIRNLLGDFKGT------NKTSPKDLVRLAALVSNNKLLSTKSNS +QVMNIMSRCHN-RSLLPVGLGKGAKIAHKTGTLGR-VLGDAGIIQTPSGKRYLAGIMVAR +PFGD-VRARTFINEVSRLVYG-- +>[subseq from] Uncharacterized protein n=1 Tax=Oscillibacter sp. TaxID=1945593 RepID=A0A350TJS3_9FIRM +---LQDALEQAVEAHSGAYAVTCASADGSWSV-DVNGDKPFVSASIIKLAILGTLLDQAQ +SGVLSLDGTVTVSPSDIVGGTGVIQASGAGEYTYRQLAAYMIQDSDNIATNLIIDAV-GM +PAVNEYASEIGLTQTVLNRRMMDFAA----GDENYTSANDVARMLQLIYQGKLVSSDMSE +FALDLMKGQHD-DAGLLEGLPVGSVFAHKTGTLD-GVFNDGGIALAPN--PYVMVVLSSD +AERSQ--AQACMVDIAQAA---- +>[subseq from] serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=UPI0004177EA6 +-tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGNKKVLSASMIKLLILAELMKKVS +ENKFSLSDAITVTEAMKTGGDGVLKELNSGHFTLKELTTLMIIVSDNQATNILIDFL-GM +ENINQLGKELRLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQEKLINKEASQ +LILDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILVVLTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Uncharacterized protein n=1 Tax=Sphingobium chinhatense IP26 TaxID=1346790 RepID=W1KKU6_9SPHN +----------LGTSFKGKVGISVRNMDEGWMV-SFNGGRMLPQQSVSKLWVAIAVMDAVD +HGALSLSDPVTVRRSDLTVHQPIRPLVTKAGTTIGKLLEMALTRSANSCNDVLLWKVGGP +EAIRAMLKRKRINDVGFGPGERKLQARYLANPYDGASANGVTLGLMLLKQGKLLSKSSTR +HLLSLMRASRTGPLRLRSGLRNGWTLAHKTGTGQTTGYNDVGILVSPEGHRYAVAVMIAS +TRAPIPARMRLMGDVTRAVIR-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus butanolivorans TaxID=421767 RepID=A0A0M0ESF2_9BACI +-qTIEHEILALVETFDGRIAYKIEN-ADGDTI-SYHDDESFQSASLIKIPMIIEGYRQSE +EKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMTLL-GN +DEINQCIKELGLKNTILGRRMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE +KILRAFDNQQL-RDKLPSLMGKGVKVASKTGAIR-GVAHDCAIIRSEFQT--VYAVVLTE +DMKSEDESRQVISKIGKLIYD-- +>[subseq from] serine hydrolase n=1 Tax=Acidovorax citrulli TaxID=80869 RepID=UPI00069803A9 +------------------------------------------------------------ +----------------------------------------------------------GS +QRVQALARTLQVQKDDLKKTIEEAYDRYYAWGTNTATLAGYGGMLEKLVRGQLLTPPHQQ +MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAQAIVVATCAE +DMDEMRQAGRLFEQLGRAITR-- +>[subseq from] Serine hydrolase n=1 Tax=Rufibacter tibetensis TaxID=512763 RepID=A0A0P0CIT2_9BACT +----REEVLAELGKQKGTFAVAFKDLKTGEEL-LLNEHESFHAASTMKTPVLIEAYKQAS +EGKFAITDSVLVKNESIVDGSPFSYSQLGQKRPLSELLYKMIIQSSNLATNIVIEKL-DA +KNVTQTMRDLGAKDMQVLRGVEDTK-AYRQGMNNTTTAYDLMVLFQKMALGKTVSKSASQ +EMIKILLEQKF-KDVIPAKLPQEVTVAHKTGWIT-GVRHDSGIVFLPDGRQYVLVLLSKG +LE-DEKAGIEAMANVSQMIYQH- +>[subseq from] serine hydrolase n=1 Tax=Acinetobacter seifertii TaxID=1530123 RepID=UPI0012504791 +-nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPT------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=2 Tax=Bacteria TaxID=2 RepID=UPI0009906C8C +------------------------------------------------------------ +-----------------------LEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A350D5P7_9BACT +-------ILKRISNLRGQTGIVVEDLETGWTF-IHNEEQPFPAASLVKIPIMVACFKAAG +EGLLDLSGKYVLKRKDRVGGSGRLRRMRNGRFTFAQLIDYMVTESDNIACNILIDRL-GF +DYINNVFDELGLKKTRLNRKMIDFAAR-DQGLENYTSAAEMTGLLERIYHRCCYNAVISD +QCLAVLKRQKI-NDRLPRYLPKEVTVAHKTGLEKE-VCHDAGIVFTPNGD-YIITVLVHT +W---------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus caseinilyticus TaxID=1503961 RepID=A0A1H3UGY3_9BACI +-----GEITKIIGEAAGSFGVAIKHVESGQEV-IINGEKQFEMASVFKLPVLVALLTNAA +PRAVSLDTRMEIRQNDRVPGSGIIKELDEGLMTIRDLATLMIIVSDNTAADMVLHMI-GK +ENVNRKMKELGLENIVVRQSCWELLTMENTRQGNRATVTDTNALLEKIVTRRI-EVTASK +QIIDILSRQQY-RQRLPSLLPPATKTANKTGTIGT-VVNDAGILFLPDHKGTLIITVFSE +GNRTLAAGENVIAKIAKTAFDHy +>[subseq from] Beta-lactamase n=3 Tax=Bacteroidales TaxID=171549 RepID=A0A412N9W8_BACVU +---ISDSISKIASEYPGEIGVAVI-INNQDTV-TVNNKSIYPMMSVFKVHQALALCNDFD +KKGISLDTLVKINREKLDPWSPMMKDYSTSVLTVRDLLRYTLIQSDNNASNIMFKNILNT +AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAILMNRLFTESLISNEKQN +FIKNTLTECKTGVDRIVAPLKEGVVIAHKTGSGCNGAHNDVAFIRLPNNKYYTLAVFVKD +FKGNEKQAAKIIARISGTVYS-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides salanitronis (strain DSM 18170 / JCM 13567 / BL78) TaxID=667015 RepID=F0R526_BACSH +---LTDSISRIVSACPGEVGVALI-VNNSDTV-TVNNKSIYPMMSVFKLHQALAICNRFD +QDGLSLDTSLTIRREDLDPWSPMLKEHREPLLPVRDLLRYTLIQSDNNASNLLFERLVSV +AETDSFIATIPRSSFRIAYTESEMAADHAKAYANCTSPLGAAMLIHRLFTDALVSREKQD +FIMKSLGECTTGKDRIAAPLKEGISIAHKTGSGYTEAHNDVAYICLPNGVSYALAVFIKD +FKGNESQASQVAARISAAVYS-- +>[subseq from] Uncharacterized protein n=1 Tax=Prevotella sp. CAG:617 TaxID=1262933 RepID=R7PDW2_9BACT +--GLAEQIVELTTRCRAQTGVAVIM--GRDTV-CVGNDTHYPMMSVMKLPLAVWVVDSLL +HHGCSWRDTVEVDSASLLPYSPMRQQYPRGGFSMEQVLNYSLQLSDNNACDWLLHRSGGP +RAVERFLRRRGLTNISIQFTEDDMHVDPRRAYGNWTTPLEMARLVAMLLEGRLTDERGQE +WLRGSLLQCQTGQNRLARPLETGAAFGHKTGTSDRDAMADAGFVRLPDGRKYVIVVFVKD +AAESDARVEQLMADVSELVYR-- +>[subseq from] serine hydrolase n=1 Tax=Virgibacillus sp. LJ137 TaxID=2293253 RepID=UPI000F489070 +--DVQQRIEALCDAAGGSWGIMLMDLDNGSSW-GMNETQPYTAASIMKIPIMATVLQAHE +SGKFQLGDKLILKKEDLVGGAGVLQHMTPGTLTVYDLMMLMIIQSDNTATNILVDLV-GI +KTIQQYLKVHGFEGTSFYNKLMIVPAK--RKGPNLITAVDMGRLLTEIAQGHMISLQASE +RMIDILKKQQL-QDCLPALLPEQWEIAHKTGSVQ-GILHDVGILYVGQRK-LVAAILSQG +LDK--LAAQSVIQKIGLELYR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Psychrobacillus psychrotolerans TaxID=126156 RepID=A0A1I5Z3R3_9BACI +--NLQQKIESYIDTVDATFGIYIKHLGTNEEV-NIKEHQLFQMASVVKVPILVTLYEKVY +KGEIDLQQRIKLVEEDYVPGSGVFQEMEYGIPTIKDLATMMIIVSDNLAADKVLSILGGT +HQVEEKMHQLGLSNIYTKHTIWDLLSFQESTENNVSSAKDMSLLLEKIALGDIVSEECSR +EIREILFKQHF-QQRIGGLLPRNKKVANKTGSLGT-MFNDTGIVYLPDNGEFVITVYSVG +NSLE-YKGDEPIARIAEIAYQHf +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6FG45_9BACT +------------------MGVAILDLSDGRIL-LRNADRVFPTASSIKIAVLLELYRQDQ +KGKAKLDDIYTFDPKDLVEDSQIMSGLTPGVVTNRDLAQFMVAVSDNAATNVLIDHV-GM +QNVNATLRSLGLTKTMLRRKMIDIAAARRG-DENVSTPQEMARLLEMIYKGKALNQELTG +DLIKQLKTLKK-DSYLSYELPADVELADKPGSLD-GVRTDSGIVFAKNR-PFAISVMTTY +DR-DEKAAERAISEVALEAYRYf +>[subseq from] serine hydrolase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI00119D4B4E +--TIEHDILALIETFNGKIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESQE +RILRVFDNQQL-RDKLPSLMGKGVKVASKTGGIR-GVSHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKLIYD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI0011A3B828 +-qTIEHDILALIETFNGKIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLENTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESQE +RILRVFDNQQL-RDKLPSLMGKGVKVASKTGGIR-GVSHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKLIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Acidovorax avenae subsp. avenae TaxID=80870 RepID=A0A2R4EBJ0_9BURK +--PLERALARVEADSGVRIGVYVRDLDTGASA-SLHGTEPWYLASSVKVPVAIAVLRGVE +RGDFTLETPLTLRAADYVDGAGPTNRAVGTPLAVRYLLEQMIIYSDNTATDMLIGLV-GI +GTVNAVVQSLVPRGFGRITSLADVRRTYYATGLNSGHLDAYADLLQALVEGRALDARHTA +YLLSVMERVKTGTQRIKAGLPPGARFAHKTGTQR-ARTCDSGLVTVPRSGPRVLVVACTR +GEPSTARSDRALRQVGIALC--- +>[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium nucleatum subsp. animalis 4_8 TaxID=469607 RepID=R9REA2_FUSNU +-tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGDKKVLSASMIKLLILAELMKKVS +ENKFSLSDAITVTEAMKTGGDGVLKELNSEHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINQLGKELRLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQKKLINKETSQ +LMLDILLRQQQ-GERLQRYLSSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILVVLTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Beta-lactamase class A n=1 Tax=Ohtaekwangia koreensis TaxID=688867 RepID=A0A1T5IQT9_9BACT +-eKLGKNIASVLGQQSGVFAVAFKDLTTGEEI-LIDERESFHAASTMKTPVLIEVCKQVV +AGKFSLTDSIVLKNESIVDSSVFTYNHLGEKRSISSLAYDMIIASSNLATNLIIELV-DA +KNVTQTMRDLGARDIQVLRGVEDAK-AFDRGLINTTTAYDLMVIFEKIANGEAVNPEASQ +IMIGILSDQKF-NEIIPAKLPKDVKVAHKTGNIA-GVNHDSGIVFLPDGRKYIVVLLSKE +AK-DEKAAIAAMASVSEMIYSY- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=UPI000FF85698 +---ISDSISKIASEYPGEIGVAVI-INNQDTV-TVNNKSIYPMMSVFKVHQALALCNDFD +KKGISLDTLVKINREKLDPWSPMMKDYSTSVLTVRDLLRYTLIQSDNNASNIMFKNILNT +AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAILMNRLFTESLISNEKQN +FIKNTLTECKTGVDRIVAPLKEGVVIAHKTGSGCNGAHNDVAFIRLPNNKYYTLAVFVKD +FKGNEKQAAKIIARISGTVYS-- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=UPI0006C9EF28 +----EQRITTLIQESPYNVHLFIKNLTTNQLLiSHQLETSFSSASLIKVPILLALLSYIE +KNKLSLNSTLTISPTDWVDFSVISEQRLTQ-STFYDLLLWMIITSDNTATNVLIEVV-GM +EYLNDYFQHIGLQDTLLQRKMMDVER-LAKGIDNRTSARDMAHLYTRIYQQELLTPTYNK +LVINILSRQRI-HDSLKRYLVEDVRLAHKTGGLDT-VDHDVGIFYTNAV-DYSMGVFITN +VT-DNDQARQLIGRLSKVVYDQ- +>[subseq from] Serine hydrolase n=1 Tax=Gemmata obscuriglobus TaxID=114 RepID=A0A2Z3H5M8_9BACT +--DLESRITPLVKEHKGKVAVAVKHLKTGEEF-YLNADEPMPTASLIKLPIMVEAYWQAK +EDKIKFDKPVTLAKGDKVPGSGILTPHFSEGFPLKDAIRLMIVYSDNTATNMVIDQI-GL +PATGERMAQLGLKNTKVNAKVFKPETFGKKYGLGSTTAKEAVRLLELIDAGKVVSPEACK +EMLGHLKACDD-KEKLVRFLPAGTVVAHKSGSVD-ASKTDAGIIYTKGG-PIAVCVLTDA +NEAADNAGQVLIGKVAKEVFDHf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides reticulotermitis JCM 10512 TaxID=1445607 RepID=W4UWF3_9BACE +-------------------------------------------MSVYKFHQALALANYME +QRNLPFETILGITQSDLKPYSPLRDQYPNGGMSVAELLKYTLQQSDNNACDILFRYQGGT +GAVNRYIHSLGITDCLISATEEEMHQDLERCYQNWTTPVAAAGLVDLFLRKPLFGAAYKD +FIYQTMVECQTGKDRLPAPLTKGVIIGHKTGTGGLNGTNDIGFILLPNGHRYSIAVLIKD +SEENPQATSGLIGEISRIVYEY- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium 13_2_20CM_2_66_5 TaxID=1805203 RepID=A0A1Q7AVU0_9BACT +---LKARVQARILQTPARVGLYYRDLTTGDSL-TVGSDVRFHAASTMKVPVMIQLFRDRD +AGLLSLDDSVTITNTSIVDSSPYRYKRLGQRASIRQLIELMETVSSNLATNLLIAKV-DA +KRANATAHALGADSILVLRGVEDD-KAYRAGLNNTTTARDLGMLLAAIANGKAASAASCR +EMLAILGRQQF-NEGIPAGLPPGTTVYHKTGWIGQVVYHDAALVEPPNGGRYVLVVLTGA +IQKD-ADAHAAVRDLSKLVFD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax radicis TaxID=758826 RepID=A0A561D152_9BURK +---LQAELVQVAAQNTAGIGVYVRDLETGIAV-SHRGMERWYLASTVKVPVALAVLQAVE +RGDFALDTKLRVRASDYVDGAGQTNSPVGTALSVRYLLEQMLIYSDNTASDMLIGLV-GI +RAVNALVEQLVPRGFERITSLADVRRAYYAGGLNSGRLDAYADLLELLVNGKIVNPEHTR +YLLAVMERVQTGVYRVQAGLPKAARFAHKTGTQR-ARTCDSGLVTVPGRDRRVIVVACTR +GELSSARSDRALRDVGAALCQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus choshinensis TaxID=54911 RepID=A0A0Q3SY28_BRECH +-eQLRQKLSDLLAKAQGSWGVVVEDLDHGTRF-EHRAEESFIAESVIKVPIMAAVYAAAD +RGQFTMDDRLSLRKEDLVKGSGLLYTLSPGLLTIRELVTLMIIQSDNTATNVLIDLV-GK +ERIDQTMFELGMQQSKYSRKLMIYPVD--ISENNTITACDVSRMLGRLATSKFLSHRACE +EMIGIMKKQQV-RNGLPSLLPTDWEIACKSGWDT-GRQHDVGVLYVGDRR-FSIVALSQN +VQ--AEAALEVLGQLGKEVYEY- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5KLV7_9BACT +-kKLETRVEEIAGRLDGVMGAAILDLTDGRIL-LRNADRVFPTASSIKIAVLLELYRQDQ +KGKAKLDDIYTFDPKDLVEDSQIMAGLTAGVVTNRDLAQFMVAVSDNAATNVLIDHV-GM +QNVNATLRSLGLTKTMLRRKMIDIAAARRG-DENVATAQELARLLEMIYKGKALNQELTG +DLIKQLKTLKK-DSYLSYELPADVELADKPGTLD-GVRTDSGIVFARNR-PFAISVMTAY +DR-DEKAAERTISEVALEAYRYf +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=D1LFC7_ECOLX +---------------------------------------------------AAAVLKQSE +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGTTT------------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase class A-like protein n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=A0A2X0XS56_LYSSH +----EQRITTLIQESPYNVHLFIKKLTTNQLIiSHQLETSFSSASLIKVPILLALLSYIE +KNKLSLDSTLTISPTDWVDFSVISEQRLTQ-STFYDLLLWMIITSDNTATNVLIDVV-GM +EYLNDYFQHIGLQDTLLQRKMMDVER-LAKGIDNRTSARDMAHLYTQIYQQELLSPPYNK +LVIDILSRQRI-HDSLKRYLVEDVRLAHKTGGLDT-VDHDVGIFYTNAV-DYSMGVFITN +VT-DNDQARQLIGCLSKVVYDQ- +>[subseq from] Beta-lactamase class A n=1 Tax=Sediminibacterium ginsengisoli TaxID=413434 RepID=A0A1T4K2J1_9BACT +--TLTQKIQQLLSGQQGVFAVAFKDLATGETI-LINEKTMFHAASTMKTPVMIELYKQAA +AGTFSLQDSALVRNESIVDGSLYRYRREGERLSLNELIYQMIIRSGNLATNILIEIL-DG +KKITATMRELGAPDIQVLRGVEDQK-AFDQGLNNTTTAYDQMKIYEALANGKAVNKDASD +AMIRILLDQQH-NTVIPALLPKDVKVAHKTGSITS-VHHDAGIVFLPDGRKYVLALLSAK +FT-SDKEATGAMARVSQLVYRY- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI0004FF95F4 +----ENQIQDLIQKTPYKVHLFVKDPKTEQFLfSHQLEESFSSASIIKVPILLAVIAYTE +KHNISLHSALTITPADWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM +DFLNDYFRQIGLQETLLQRKMMDVER-LAMGIDNFTSARDMAHLFTRIYQQDLLASPYNE +LVIDILSRQRV-HEGLKRYLVDDVKLAHKTGGLDT-VDHDAGIVYSSSFD-YLIGVFITN +VT-DNDLARQLIGRLSKVVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus invocatus TaxID=173959 RepID=A0A3M8CMB4_9BACL +--SLSPSIAPLLEESGGEWGVYLEDLHTGEQL-SFNQNERFYAASVIKVPIMAAVFAEVS +AGKFALETIIRLRQEDQVGGAGILQHMTPGSWTVQDLVTLMIIQSDNTATNMLIDLV-GK +ESIRSIMQATEMTNSHFYNKLMIVPAQVEG--YNEVTAADLGNHLRYLAKGKVISYDSCA +RMMAILKQQQH-RDRIPLHFPPSWELANKTGSVTN-ITHDIGILYVGSSA-VTICVLNKG +LP--QKAAVQTIASIGKLVFDLy +>[subseq from] serine hydrolase n=1 Tax=Numidum massiliense TaxID=1522315 RepID=UPI0006D57C51 +-eQLKQTLEQLMEKAGGMWALVVDDLDRQTQW-AHNEEELFYAASVIKIPIMAAVFAAAA +RGNLRLSDRVTLMREDIVGGAGVLQHMTPGILPIVDLLTLMIIQSDNTATNVLIDAV-GK +PFIRETMRELGMSRSEFHHKLMIVPAKTKG--YNVITAADMSCLLARLAHGKFLSRHACE +QMIAILKKQQF-RDCLPAHLPEHWELAHKTGWVT-GIRHDVGIFYVGNR-CMTVALLSRD +VD--DFVARQTMAAVGRHIYEY- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI000C265912 +------------------------------------------------------------ +-----------------------LEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] serine hydrolase n=1 Tax=Mycobacterium tilburgii TaxID=44467 RepID=UPI0011820C68 +------------------------------------------------------------ +----------------------------------GQLCAAALQRSDNTAANLLLSAIGGP +PAITDFARSIGDELTRLDRWELELNTAIPGDLRDTSTPRALGTGIRKLLTGTVLGQAQRG +QLEQWMRGNTT--SSMREDLLPGWSSADKTGTGDYGSTNDVGMVYGPAGQRILVSIMARS +QSPDAAALRPLIADVTRSVL--- +>[subseq from] serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=UPI0001D0A9E7 +-tEWKKKIEKIISQVEGNVCINFYDLNKNNGF-SVNGDKKVLSASMIKLLILAELMKKIF +ENKFSLSDTVMMANFMKIEGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINQLGKELDLKETFLGRKMMDAEA-RKKGYDNYTCADDISLLLKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGDRA-YILVVLTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Serine hydrolase n=1 Tax=Xanthomonadaceae bacterium NML93-0792 TaxID=2032566 RepID=A0A2A3VG77_9GAMM +------------------------------------------------------------ +----------------------------------------------------------GE +ARVRKLAQILGVTPTELLPDLDSAFESYYATHANSASLRDYGRMLAALQQGRALDAEGTR +YLLDVMGRVQTGRQRIRAGLPAGATFAHKTGTQYR-RLCDSGIVTMPSAPRVVIAACVRG +AT--GAAGERALRDIGAAVT--- +>[subseq from] Serine hydrolase n=1 Tax=Haliea sp. TaxID=1932666 RepID=A0A519HLL0_9GAMM +------------------------------------------------------------ +----------------------------------------------------------GP +KRVDNIRRALNLQPGNLQATIDDAYARYYRTNVNSATLQAYGDMLEKLVKGQLLKPASMQ +RLFTDMKIDIYTNYRVQAGLPRSVKFIHKTGTQYR-RACHVGVINPQNNAANAIVVTTCA +ADDEQRQAGAVFQQVGRAVTK-- +>[subseq from] serine hydrolase n=1 Tax=Comamonadaceae bacterium ALPHA2B TaxID=2502232 RepID=UPI0010F8EEEF +-eALGAQIERIDRGTPGELGVFVKRLDGGETY-RHGAERFWYLGSMTKVPIAIAVLQQVD +AGKLKLSDTVELQDADRIDVSRVVRERTGRRYTVDALLDRMLKDSDNTAANMLIRTV-GE +DTVQRAAQALGTQGFK-------------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Comamonadaceae bacterium ALPHA2B TaxID=2502232 RepID=UPI0010F8EEEF +------------------------------------------------------------ +----------------------------------------------NTALVQVANAPLGP +GRVQAVQRALKLKDGDLQRTIDDAYDRYYRHDINSATLDAYGAMLEKLVRGELLQPASLQ +RLYAAMKLGTFTNHRLQAGLPRGEPFIHKTGTQYE-RACHAGVLRPQDRAHAVVVAVCAA +GMDEHKDVDAIFQQVGRAVAQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Tumebacillus permanentifrigoris TaxID=378543 RepID=A0A316DZR3_9BACL +--ALSEQLTKCLQAAQGTFGVAIHHFQSQETF-HYNADEVFFAASIIKVPVMAAVFDQAS +KGVLTMAETMTLRTEDKAPGSGILSNLSTGLISIWDLVVLMIIESDNTATNMLIDRI-GM +ETVQACMQEWGMEQTRIYNKLAVIPAN--LQHVNTISPREMTDFMIKLAESKIVSWKACR +EMVDILKQQKF-NDGIPSLLPPTFEMAHKTGWVRT-VENDCGLLYFPGHT-FAISIFTKD +VT-DKPATKRVMGEIGLHLYN-- +>[subseq from] Beta-lactamase class A n=1 Tax=Novosphingobium kunmingense TaxID=1211806 RepID=A0A2N0HK34_9SPHN +---LQTALNDIAARFQGKVGIAINQAGCKWLV-GVRADEYFPQQSVSKLWVSLSVLDAVD +RGQMRLDEPITLRPDDQVVNQPLRWTVLDQGLPAQTLMQDSLSLSDNMANDKLLWRVGGP +DHVRMVLSERKIEGIRFGPGERLLQSKYVADPMDGATPAGIASALGRLGGGELLSEQSTA +LLLDIMAHSKSGPRRLKGGLLPGWKAYHKTGTGQQTGFNDVALVEAPDGTRYGVAVMIGE +TRLPNPARLEMMQAVSRALVA-- +>[subseq from] Beta-lactamase n=1 Tax=Stigmatella aurantiaca (strain DW4/3-1) TaxID=378806 RepID=Q098G1_STIAD +-------------------AVAYRDLGDSRDAvFLEADTSFHAASTMKVPVMIEFFRQVD +AGVLALDQPIVLTNRSIVDGSPYSYEHLGRPMPASELLKRMITRSSNLATNSLIALV-GA +KRVTRTLRTLGAPSMTVLRGVEDGK-AYAKGLNNTATARDLATLLAALEQGKAASPRSTQ +AMRDILLAQEL-NALIPAGLPPGTPVAHKTGQIT-AVLHDAAIVYPAGRAPYVLVVLTRG +IA-DEQVARALIVDLSRSVHA-- +>[subseq from] serine hydrolase n=1 Tax=Pseudorhodoferax sp. Leaf274 TaxID=1736318 RepID=UPI0009E8830F +--RLSAELERIDAAPDGRIGVYVRALSSGESL-SFRADQSWYLASTVKVPVAIAVLRGIA +RGAYTLDTPVTLRADDYVDGAGSTNSHAVGTLPIRTLLEQMIIHSDNTASDMLIGLV-GL +EQVNAVVTEVAPAGFGPITRLAEVRRAYYATGLNAGRLDAYGELLAQLADGRLLPPTQTR +HLLGLMERVVTGPQRIRAGLPAGMRFAHKTGTQR-GRFCDAGIVQPAGGATRVLVVACTR +GELSLVRAERALREVGAALC--- +>[subseq from] Serine hydrolase n=1 Tax=Caldilineae bacterium TaxID=2420332 RepID=A0A3M1FGV3_9CHLR +--NLRDELAAIIQESGAEMGVAIRHLETGEEI-NIHGDRVFPLASVFKIPVLVEAFRQIH +AGKLTLDERHTLTVTEKNLPSGVLVFFDDGLPTFRDLLTLMIIISDNTATDMVMHRL-GA +GAVTRTMHDLGLTDIHVPITVREIFDYSLGPDNNVGTPRALTQLLSMIWHGQIIDRAACD +AMLAILLKQQL-NDRLPRYLPPGTPCAHKTGTLP-GLRNDSGIIYVDDHNHVAVTVFSRW +DDEA------------------- +>[subseq from] Beta-lactamase class A-like protein n=1 Tax=Acidaminococcus sp. CAG:542 TaxID=1262687 RepID=R7M167_9FIRM +--------------AAGPAQVYFTNLSTNQSL--YRGSETMTAASMIKVFILAKAYEDIQ +NGSLSRNETFTLTPDNVVGGAGVLQGRGYGSVSLQEALELMITESDNTAANLLIDRL-GM +DRINAYMQRHGYTHSVLRRKMMDTE-AMAAGRENLTSTRDIALLFKRLYQGKCVSPAQDR +EMLAIYKRQTD-NDSIPGDLPRGTVVAHKTGEVND-LRHDGGIVYTPNGD-YVLVIFTRN +YTP-YETMADLSEKIYQAV---- +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus varians TaxID=1145276 RepID=A0A4U2YGB1_9BACI +----QPTIQRIIQEAPYKVHMFVKDFKTNDFViNECLDEAFSSASLIKVPILIAIFDYID +VCNIPINQVIAISPSDSVDFSVISEQRVT-SCTIYELCVWMITTSDNTATNVLIDVI-GM +EALNKYFHKIGLTHTQLQRKMMDFER-LAKGIDNITTARDMAHLFSQIYRQNLLSPVLSQ +LAIDILCRQRF-HECLRRYIVDDVTIAHKTGGLDT-VDHDVGIVYSHVQD-YGIGVFISE +VKH-NDVARQLIGRLSKVVYDK- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2G6Q4K1_9BACT +-kDLDRQINEILAGQPGVYSVSYRDLASGREW-HFNADDRMHAASTMKVPVMLRVFQKLE +QENKSLNDALRVHNSSIVDGSAFAYQFLGKNVPIEHLVRLMIIRSSNLATNILIDWV-DA +KKVTELMVELGARQTSVLRGVQDLK-AFEKDMNNTTTSRDMLQILISCYQSELFTKTSRD +AMIQFLLDQEF-NDLIPAGIPANAKVAHKTGSISR-VHHDAALVMLPDGSSYGLVVFSRD +FGEERERVKQTIRNISSAVYQY- +>[subseq from] class A beta-lactamase n=1 Tax=Moraxella catarrhalis TaxID=480 RepID=UPI000EAA6877 +-------------------------------------------------------LLLVD +KEKLDLNEKIIIKESDLIEYSPVCKNYFDENISISELCEATITLSDNGSANILLDKIGGL +TAFNQFLKEIGAD-MVLANNEPLLNRSHYGETSDTAKPIPYTKSLKALIVGNILSNQSKE +QLITWLINDKVADNLLRKYLPKNWRIGDKTGTGSE-SKNIIAVIWNENNKPYFISLFITQ +PHDGKNQKDEIMAQIGKEIY--- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3C1YRB7_9BACT +-eKLTAKIKQIVEQADAVVGVAIKDLRSGEQI-LFNEDEIFPQASSIKIHILSEVYKQAA +EKKFNITDIKQLPITARVGGSGILSSLGEKSLSIRDYCVLMIVLSDNSATNLLIDLV-GM +KNVNESLQKNGATKTKLQRVMMDIQAA-KEGRENISTPKDVLVILDKMYNGTLVNKQASD +DMLSIMKLDKD--GALKSGIAPDVSIANKGGDVE-GVRTDVGIIYLENN-PYSICVMTKM +LVH-NEDGSKIITDVSHEAFNYf +>[subseq from] serine hydrolase n=1 Tax=Peptoniphilus raoultii TaxID=1776387 RepID=UPI0008D95A8C +--ELKAKIENYIEENKGNICLSYYDLDKGEGL-SIKGEEKVPSASMIKLLIMATLLKEVR +EGKISLEEKIKISKDEYCGGSGILKELDPGHLTIKELMTLMIIVSDNLATNILIKLL-GM +KKINEMGLELGLKNTFLGRKMMDGEAK-SLGKDNFTSADDIKNILKLVYKKELVDEKSSD +LMLELLLSQHE-RERLQRFLGEEVKIANKSGDLDF-LENDGGIFFLEHK-TYILVILVSK +AS-SNYEAKEIIGKISKFIYEE- +>[subseq from] serine hydrolase n=1 Tax=Cyclobacterium xiamenense TaxID=1297121 RepID=UPI0012B8A053 +-----------------------IQGAEGEILaEYEPDKGVPSASIIKIPILLALLEAVE +NEELSLEDRYHLRNQDKVGGAGELQFEPDGSLTYRTLATEMIRISDNTATNILIDEL-GM +ERIQGWLNERGFTATQLNRKMMDFA-AIEQGKQNYTSPAEINRILLMLLDSKSVSAETAA +SARQLLTACAD-RQTLPALLPKNLEVAHKTGTLDY-VRGDAGIIFG--KRPLVVSVFVEH +FQ-EIEEAEKIIAEIGRLAYEIy +>[subseq from] serine hydrolase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI000D152DAE +------------------------------------------------------------ +----------------------------------------------------------DP +QRVQALARSLHVRKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ +MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAHAIVVATCAE +GMDEMRQAGRLFEQIGRAITR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. OK042 TaxID=1884381 RepID=A0A1I3WFG3_9BACL +--SLSTQIAQLVENAGGEWGIYLEDLQTGETL-AFNEHKRFYAASVIKVPIMTAVFAEAY +AGNIALEQKIKLRQEDLVGGAGVLQHMTPGTLTVQDIVTLMIIQSDNTATNILIDLV-GT +ESIRAAMQKTGMANSQFYNKLMVVPAELEG--YNELTAADMGSHFRYLASGKVISYDSCL +KMMAILKQQQH-RDRIPFHFPPKWELANKTGSVTH-ITHDTGVLFVGPHA-VTICALNKG +L--EQIPAAQTIAEIGRLVYNLy +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus sp. AFS017274 TaxID=2033488 RepID=A0A2A8TN97_9BACI +--TIEHDILALIETFNGKIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLENTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESQE +RILRVFDNQQL-RDKLPSLMGKGVKVASKTGGIR-GVSHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKLIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A1Y4WW84_BREBE +---LFAQISSLIKDAGGEWGIFFEVLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY +AGKFAFEDKIKLRTEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT +ESIRNAMQKTEMTNSQFHNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKIISYDSCL +KMVAILKTQQH-RERIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG +LE--QKDAANVMAQIGNLVYHAy +>[subseq from] PG_binding_1 domain-containing protein (Fragment) n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E7L3Y4_9PLAN +-kSLRQKLSSLLKTHEGHVAVAIKHLATGERF-EFEANRAMPTASLIKIAVMVEAYRQAD +AGRIDLEQRITLLAGDKVPGSGILTTHFSAGVSLRDAIRLMIAYSDNTATNLVLEQI-GI +RSTSKTMEKLGFPNTKIHAKVFRRDTRSKRFGLGSTTALETVQLLEQLYRKQLASPSASD +AMLKHLENCQD-RTKLRRFLEPHITIAHKTGSLAT-VRTDAGIISSPSG-PLVVCVLTSE +NKTEENAGEILCARVAKITCAHf +>[subseq from] Beta-lactamase class A n=1 Tax=Larkinella arboricola TaxID=643671 RepID=A0A327WPN5_9BACT +-kELRQQIERELSQQPGTFAVAFRDLKTGQEL-LIREHENFHAASTMKTPVMIEVYKQAA +QGRFSLSDSMLIKNESIVDGSPYSYTRVGTKRPLSALVYDMIIVSSNLATNLVIELV-DA +RKVTQTMRDFGAKNIQVRRGVEDKK-AFDQGLNNTTTAYDLMVIFDKMASGKAVSPEASA +DMIRILLDQRF-NTVIPAQLPNDVKVAHKTGSIA-GVHHDSGIVMLPDGRKYVLVLLGKD +LN-DESASVRSMATVSRLIYDY- +>[subseq from] Beta-lactamase n=1 Tax=Peptoniphilus sp. ING2-D1G TaxID=1912856 RepID=A0A090HZ88_9FIRM +---LKLKIENIIRRTKGKVCLCFYDLKENKGF-GINELQKMRSASTIKLLIMAELMRRVK +NKEFSLSDKIAVTKDNFTGGDGILKELEYHHFSLKELVTLMIIVSDNEATNILIDLL-GM +ENINKLGKNLKLKEADLQRKMMDSE-ALAKGYDNYICAEDLKTILQKIYEGKLINKKSSE +IMLDILKRQTQ-GERLQRYIAEELTIAHKSGDLDN-LEHECAIIFLEDMD-YIIVVMTDD +MN-SNLEGREIIGKISKTIYDE- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Elusimicrobia TaxID=1797919 RepID=A0A1F9S063_9BACT +--AMTADVEASARRYPHRVGIYIKDLHHNLEW-SYHADDLFPAASLIKVPVMCGVFEKIH +RGELSLNSQLTLRRRTRMGGSGSLKWAREGSYTVRRLLEKLIHESDNSAMMLLIDEV-GM +GYLQRFFPSMGLVYTEIYPDGLRLTSG-SVRYENYTTPREMGGMFEKMYRHQMVDQFASE +LMLDILKSNPS-RSRLAKELPVGWELAHKTGLLRR-ACHDVGIVFSPQGD-YVIAVLTGR +NQ-SYTAAKDLIINLGKTTYKYy +>[subseq from] Beta-lactamase class A n=1 Tax=Singulisphaera sp. GP187 TaxID=1882752 RepID=A0A1N6JE71_9BACT +---LERTLRAIVEP-AGEVAVVYTNLADGEQV-FIKGDERIHPASTMKVPVMMEVFRQAE +LGTLALDGGIRLKNDSIADGSRFTYRHLGEERPVRELVRLMITESSNLATNLLIERV-TA +PRVSELMKAMGAGDVRVLRGVED-NRAFERGLNNETTARGLATILQQLAARRVVSVKASE +EMLAILRGQKF-NEGIPAGLPAGVPVAHKTGSIT-AIAHDAGVIEPAGRAPYVLVVLTRG +IK-DSAKAHELIARVSRVVYEH- +>[subseq from] Beta-lactamase class A n=2 Tax=Brevibacillus TaxID=55080 RepID=J3BB11_9BACL +-------VSELLEAAGGEWGVYLEDLQTNEKL-AINENQRFYAASVIKVPIMAAVFAEAY +AGKLALGDKLKLRQEDLVGGAGVLQHMTPGTFTVYDLVTLMIIQSDNTATNMMIDLV-GA +DSIRSIMRKTGMENSSFYNKLMVVPAELEG--YNEITAADIASHLRYLATGKVISYDSCL +KMIAILKQQQH-RDRFPFLLPPKWEFANKTGSVTK-ITHDVGIFYTGPH---AISVSLLN +KGLAQKDAASVMARIGRLLYDTy +>[subseq from] BlaTEM-183_1_HQ529916 n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3P5G6U6_ECOLX +------------------------------------------MMSTFKVLLC-AVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KE-QPLLHNMGI-VTRLDRWEPELNEAIPNDERDTTMLAAMATTLRKLLTGELLTSASRQ +QL-DWMEADKVAGPLL-------------------------------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Peptoniphilus sp. oral taxon 836 str. F0141 TaxID=768724 RepID=D8FGV9_9FIRM +--KIKKHIEKIISESSGNICLSFYDLDDEEGF-SINEDKKVRSASMIKLLIMAEIMNQSK +NGKISLDTKIKVGKKDKVGGSGILKEFDCEHFSIKELMTLMIIVSDNQATNILIDLV-GM +DNINLMGKRLNLKSASLQRKMMDIK-ALEKGRDNYISAIDVKVILEKIYRKTLVDEKSSE +LMLDILLRQHE-RQRLGRFLDEEVKIASKTGDLDK-LENDGGIFFLENKN-YILVVLIDD +AV-TNAMAQETIGKISKYIYDE- +>[subseq from] serine hydrolase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0005500C1E +-qTIEHDILALVETFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE +KILHVFDNQQL-RDKLPSLMGREVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQIISKIGKLIYD-- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus acetophenoni TaxID=614649 RepID=UPI000BE2F069 +---LIEKIRSLIECVDFKVHLFVKEAKSENYIlNEKSDDIFSSASLIKVPILLGVLDYLE +KNNQTLDEELPIAIENKVEFSVVTEQNLDS-CTLYELLVWMIITSDNSATNVLIDFI-GM +EELNIYFNKIGLTQTRLQRKMMDFKS-LNKGYDNVTTARDMAYLFSRVYQQDLLSDQYSQ +LVIDILCRQRV-HEGLKRYITDDIFIAHKTGSLDT-VCHDVGIVYHPSNN-YIIGIFLTE +LA-DVEIGKRLIGRISKIVYEYf +>[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3M4H7_9BURK +--AMHRELERFARQEGTRFGVYVHDLASGQRM-SFHGDERWYLASSVKVPVAIAVLRAVE +RGDFSLETPLTLRAGDYVDGAGITNRQPVGALTVRWLLEQMIIYSDNTASDMLIGLVGEA +NAVTQLLVPTGLERITSLADVRRHAYAYYADGLNSGRLDAYGDLLVQLVDGLALNAQHTA +YLLGVMERVKTGPRRIKAGLPAGARFAHKTGTQR-ARTCDSGLVTVPAQERRVIVVACTR +GEPSTARSDRTLRHVGIALC--- +>[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Calothrix sp. NIES-3974 TaxID=2005462 RepID=A0A1Z4NJ73_9CYAN +---------------HLDAGFFFLDMETGNYI-DHNGEKIFPAASTIKFPILVALFQEID +AGRVKLNETLTMCRDLITGGSGNMQYRPGTRFSLLETATQMMTVSDNTATNMIIDRLGGL +NRLNQRFRSWGLQNTVMRNMLGDFGGT------NTSSAKDLVRLGALIANNQLLTASSRS +RVLDIMYRVRN-RSYLPSGLGSGARIAHKTGTLA-ALVGDTGIIQTPSGRRYLAGIFVRR +PRWD-DRGVELVRQVSQIFYG-- +>[subseq from] serine hydrolase n=1 Tax=Cyclobacterium sp. SYSU L10401 TaxID=2678657 RepID=UPI0013D4C43D +-------------------------NETGDILfQQNSDKSIPSASIIKIPILIALMEKVE +NEAVNLDSLYTLQASDKVGGAGEMQHLPEGSLTFRYLAEEMIRISDNTATNILIRTI-GM +DYIQQWLSKHGYKATQLNRFMMDFK-AIEAGRQNYTSPKEINEILLNLWNGAWLKEASKE +EIMHWLKGCAD-NSTIPSRLPTDTIVAHKTGTLDY-VRGDAGLILG--DKPLILSVFVEN +FQ-SMEEAEAAIGKIALKAYTDf +>[subseq from] Beta-lactamase class A n=1 Tax=Cyclobacterium halophilum TaxID=1416801 RepID=A0A1H7BVP7_9BACT +-----------------------IQGAEGEILaEYEPDKRVPSASIIKIPILLALLEAVE +KEELSLEDRYRLRNQDKVGGAGELQFEPDGSLTYRTLATEMIRISDNTATNILIDKL-GM +ERIQGWLNERGFTATQLNRKMMDFA-AIEQGKQNYTSPAEINRILLMLLDATSVSAETAA +SARQLLTACAD-RQTLPALLPKNLEVAHKTGTLDY-VRGDAGIIFGK--RALVVSVFVEH +FQ-EIEDAEKIIAEIGRLAYEIy +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. An269 TaxID=1965613 RepID=A0A1Y4FJX4_9BACE +---LTDSISRIVSACPGEVGVALI-VNNSDTV-TVNNKSIYPMMSVFKLHQALAICNRFD +QDGLSLDTSLTVRREDLDPWSPMLKEHREPLLPVRDLLRYTLIQSDNNASNLLFERLVSV +AETDSFIATIPRSSFRIAYTESEMAADHAKAYANCTSPLGAAMLIHRLFTDALVSREKQD +FIMKSLGECTTGKDRIAAPLKEGISIAHKTGSGYTEAHNDVAYICLPNGVNYALAVFIKD +FKGNESQASQVAARISAAVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Rufibacter glacialis TaxID=1259555 RepID=A0A5M8QRU5_9BACT +-qKTERQLRDLLEKSPAVTGLVAIDLTSGEAF-RFNQDQVFTQASAIKIPILLEVYKQAQ +NGKFALHHLHNIAPAQVVGGTGIIKDLPDSTFSIRNLAVLMITLSDNTATNALIDLV-GL +ANINATLQSLGLKQTRVQRKMIQGAA-SGRGEENISTPAEAAQILQMLYKGQFLNKAASA +EIVSILQKTNREASRLTSGLPAHVPLAFKPGILN-GVSTEWALVLLPER-PYAVAMMENY +KVP--GQPDRTMEEVSAVLYQYf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus parabrevis TaxID=54914 RepID=A0A4Y3PEX2_BREPA +-------VSELLEAAGGEWGVYLEDLQTNEKL-AINENERFYAASVIKVPIMTAVFAEAY +AGKLALEDKIKLRQEDLVGGAGVLQHMTPGTFTVYDLVTLMIIQSDNTATNMMIDLV-GT +DSIRNAMRKTGMENSSFYNKLMVVPAELEG--YNEITAADIGSHLRYLATGKVISYDSCL +KMIAILKQQQH-RDRFPFLLPPKWEFANKTGSVTK-ITHDVGIFYTGPH---AISVSLLN +KGLAQKDAAAVMARIGSLLYDAy +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E6J5J7_9CHLR +-----SEIKSLVSEINGEVGVAALNLKNDKNI-YINEDESFFMASVFKIPLLITLYKQVD +LGNIDMDQRITLAQDLKTGGSGVLRELTPGIPTLFDLAMLMIIISDNTATDILFNML-GK +DKINSLMRQNNLSKTFTPMSCQDLLSALNEDKSNVSTAYEMVTLMKLLTTGKILSESSTN +SVLSILKSQKL-KTIIPHYIPKNIKIANKTGGVYS-VRSDVGTVWSPKG-PYTIAIMAKN +VT-NEPDIDTKLAKISLSIYEY- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Margulisbacteria bacterium GWE2_39_32 TaxID=1817872 RepID=A0A1F6QC09_9BACT +---------------GGIVGVSIKDLTTGEYF-SINGDVQFNPASVIKVPVMVEAFHQMA +LGRISMDEKLFLHQQNKIQGSGSIQYLPNGSFTVKRLINLMITDSDNTATNMLICRL-GT +KNINQYMRKVGLRHTVLKDPTM--FCKLPG-KYNLTSPNDMLMLLEKMYKGELVSADASK +QMLDIMKAQLH-KWGIQRFLPASAIVANKTGSLDF-VRNDIGIILDKKH-PYILSIFSKQ +LP-SNYYGSVLVGSISKVIFD-- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A4U2MI98_9BACI +-qTIEHDILALVETFNGRIAYKIEN-GLGDTI-GYHETESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESQE +RILRVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKLIYD-- +>[subseq from] serine hydrolase n=1 Tax=Acidaminococcus fermentans TaxID=905 RepID=UPI0012B3528D +--------------AAGPAQVYFTNLSTNQSL--YRGSETMTAASMIKVFILAKAYEDIQ +NGSLSRNETFTLTSDNVVGGAGVLQGRGYGSVSLQEALELMITESDNTAANLLIDRL-GM +DRINAYMQRHGYTHSVLRRKMMDTE-AMAAGRENLTSTRDIALLFKRLYQGKCVSPAQDR +EMLAIYKRQTD-NDSIPGDLPRGTVVAHKTGEVND-LRHDGGIVYTPNGD-YVLVIFTRN +YTP-YETMADLSEKIYQAV---- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Margulisbacteria bacterium TaxID=2053573 RepID=A0A2W4IF55_9BACT +---------------GGIVGVSIKDLTTGEYF-SINGDVQFNPASVIKVPVMVEAFHQMA +LGRISMDEKLFLHQQNKIQGSGSIQYLPNGSFTVKRLINLMITDSDNTATNMLICRL-GT +KNINQYMRKVGLRHTVLKDPTM--FCKLPG-KYNLTSPNDMLMLLEKMYKGELVSADASK +QMLDIMKAQLH-KWGIQRFLPASAIVANKTGSLDF-VRNDIGIILDKKH-PYILSIFSKQ +LP-SNYYGSVLVGSISKVIFD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Alcaligenes aquatilis TaxID=323284 RepID=A0A3R9AGW2_9BURK +---------------------FALDAGSGRSL-GWREDERFGMCSTFKLLLAATVLDAAR +QGRLDGTAPIHFSDDDLVPHSPVLREHLALGLTAPELARATQLTSDNAAANLLIRKLGGP +EAVTALWRASGDEVSRLDRLEPDMNLLPPGDLRDSTSPRAMAQHVARLFTSEMLVPEDRE +RLREWMVETGTGLARL-------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Bernardetia litoralis (strain ATCC 23117 / DSM 6794 / NBRC 15988 / NCIMB 1366 / Sio-4) TaxID=880071 RepID=I4APP3_BERLS +------------------------------------------------------------ +----------------------------------------------------------GV +EKTNKFIKKLGLKHTIIAASEEKMHESFDNQYLNTTTPLDAVSLLKHFYQGKILKKETQD +FLWKLLVETRTGSNKIKAGLPDKIILGHKTGSSFRKAENDIGIVITEKN-TYAVAIFIKN +STESNEVNNTLIAELSKMIFEY- +>[subseq from] ClassA n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T154_9BACT +--KLAERIDSIIGDKKMTVGVAAEYADMHFV---LNDSVRFPLLSVFKTHVAMAVTARMQ +MDGISPDSVVHIDKGRLKKYSPLRQKHPDSDITIAELMRYSVAESDNNACDILIDLAGGI +DYVDMYIRSLGVSGFSISETEASMHANRQLCYANWSYPESMLDVLKVVFAP---GDTRFA +LLRGIMLGTSTGRDKIPAGVPEGIAVAHKTGSSDKAADNDAGVVMLPGGN-CYIVVFIMD +SAETDSTNAATIAAITRAVLA-- +>[subseq from] Uncharacterized protein n=4 Tax=Fusobacterium TaxID=848 RepID=A0A0M1VWP4_FUSNV +-tEWKKKIEKIISQVEGNVCINFYDLNKNNGF-SVNGDKKVLSASMIKLLILAELMKKIF +ENKFSLSDTVMMANFMKIGGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINQLGKELDLKETFLGRKMMDAEA-RKKGYDNYTCADDISLLLKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGDRA-YILVVLTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] serine hydrolase n=1 Tax=Fusobacterium hwasookii TaxID=1583098 RepID=UPI0004975C39 +-tEWKKEIEKIISQVDGKVCVNFYDLNKNDGF-SINGNEKVLSASMIKLLILAELMKKIS +EDKFSLSDTIMMANFMKTEGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLRETFLERRMMDAEA-RKNGYDNYTSADDISLLLKLIYQEKLINKEASQ +LMLEILLKQQQ-GERLQRYLPTDIKIAHKCADLDN-LENDGGIIWLEEK-VYILVVLTSR +MS--NLQCKQTIGKISKFVYDK- +>[subseq from] serine hydrolase n=1 Tax=Rhodothermaceae bacterium ISCAR-4553 TaxID=2558931 RepID=UPI00142232FC +-------LDEIVARQEAVVAVSVRDAATGTRL-DRLPDRPFHAASTMKVPVMIEVYRQAA +LGRFRLSDSLTVRNASIVDGSPYRYERLGTRMALRDLVDRMITVSSNLATNLLIDVV-SA +DSVQATVERLGGHGMRVLRGVEDLA-AYRQGLNNVTTAPALAALLEALAAGRAVSPEADR +EMIGILLEQRF-NEMIPAGLPAGTRVAHKTGWIT-GIHHDAAIVYPAGDAPYVLVILIEG +IE-DPHVAATLGADIARAVH--- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Melainabacteria bacterium TaxID=2052166 RepID=A0A327J5A8_9BACT +---LQQELVSLTEMYTVKPAIYVWDYETGNYI-DINADKSYSTASIIKIPVLIDVFKSIE +AGQLSLEDKIPLTEYYRSEGSGSLQFKARDSYTIDELAERMITESDNSATNMLMAKVGSM +TDVNQSIRDWGLKNTSVHTWLPDLTGT------NRTTAKEMAEMLYNIDEDKFLSEESRS +KMLNYMGHVHN-NRLIQAGLGAGSVFLHKTGDIGT-MLGDAGIVITPNGKKYIVVILANR +PH-NAIAGKDFIVHASEIIYNY- +>[subseq from] Beta-lactamase n=1 Tax=Cystobacter fuscus DSM 2262 TaxID=1242864 RepID=S9QP24_9DELT +----RESLQERISQVGASVAVAYQRLGGSPDAlYLEADRSFHAASTMKVPVMLEVFRQVD +AGTLSLEEPVTLTRESIVDGSPYVHERLGQSVPLRELVERMITRSSNLATNLVLSRV-DA +RRVTKTLRALGARRMTVLRGVEDGK-AYAQGLNNTATARDLASLLSALERGRAASPASTR +AMRSILLAQEL-NREIPAGLPPGTPVAHKTGQIS-GILHDAAIVYPPGQPAYVLVVLTRG +IP-DEAVARSLIVELSRQVYAH- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000E39A6F1 +----LARLAKVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRIE +QGDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +ERVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGARRIKAGLPSGTVLAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] Uncharacterized protein n=1 Tax=Peptoniphilus lacrimalis 315-B TaxID=596330 RepID=D1VS05_9FIRM +--KIKKHIEKIISESSGNICLSFYDLDDEEGF-FINEDKKVRSASMIKLLIMAEIMNQSK +NGKISLDTKIKVGKKDKVGGSGILKEFDCEHFSIKELMTLMIIVSDNQATNILIDLV-GM +DNINLMGKRLNLKSASLQRKMMDIK-ALEKGRDNYISAKDVKVILEKIYRKTLVDEKSSE +LMLDILLRQHE-RQRLGRFLDEEVKIASKTGDLDK-LENDGGIFFLENKN-YILVVLIDD +AV-TNAMAQETIGKISKYIYDE- +>[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus boronitolerans JCM 21713 = 10a = NBRC 103108 TaxID=1294264 RepID=A0A0A3IDZ5_9BACI +----EQRITTLIQESPYNVHLFIKNLTTNQLLiGHQLEASFSSASLIKVPILLALLSHIE +KNKLSLDSTLTISPADWVDFSVISEQRLTQ-STFYELLVWMIMTSDNTATNVLIDVV-GM +EYLNDYFQHIGLQDTLLQRKMMDVEQ-LAKGIDNRTSARDMAHLYTQIYQQKLLSASYNK +LVIDILSRQRV-YDSLKRYLVDDVRLAHKTGGLDT-VDHDVGIFYTHAVD-YSMGFFITN +VT-DNDQARQLIGRLSKVVYDQ- +>[subseq from] Serine hydrolase n=1 Tax=Cyclobacterium qasimii TaxID=1350429 RepID=A0A512C9G4_9BACT +---------------------YIIQDKDGKVLsKLNADKQIPSASIIKIPLLLYLMEKVE +QGELALHETYKLKNSDKVGGSGELQFKPDGHITYELLASEMIRISDNTATNVLIRKV-GL +RSFQEWLHTNGYKTTQLNRYMMDFD-AIAKGQQNYTSSAEMNRLLLSLLNEKSLNKASTL +QVIEWLKNCED-NSALPYLLPEVVAIAHKTGTLEY-VRGDAGIIFG--KRPIVLTVFVAH +YS-NLENANKIIAEIARLAFLD- +>[subseq from] Uncharacterized protein n=1 Tax=Tumebacillus algifaecis TaxID=1214604 RepID=A0A223CZI5_9BACL +--ALAPDLQRLIEAGRGTYGVSIYHLESQSEF-SYQQDESFYAASIIKVPIMAAVFDQAS +KGNLSFSEKITLRAEDKVTGSGLLQNLSPGLLSIYDYTVLMIIDSDNTATNILIDRI-GT +QAIQAAMQEWGLEGSGFYNKISVIPAKIEN--FNQITPRDMTHLLKQIADGKVVSWRACA +EMVQIMKQQKY-NEGLPSLLPKQWECAHKTGWIN-GTDHDMGLLYFPRN-TFAVSVFGKN +IT-DRKDAHSLMGQIGQLLYE-- +>[subseq from] Beta-lactamase n=1 Tax=Cyclobacterium qasimii M12-11B TaxID=641524 RepID=S7WE28_9BACT +--------------------SYIIQDKDGKVLsKLNADKQIPSASIIKIPLLLYLMEKVE +QGELALHETYKLKNSDKVGGSGELQFKPDGHITYELLASEMIRISDNTATNVLIRKV-GL +RSFQEWLHTNGYKTTQLNRYMMDFD-AIAKGQQNYTSSAEMNRLLLSLLNEKSLNKASTL +QVIEWLKNCED-NSALPYLLPEVVAIAHKTGTLEY-VRGDAGIIFG--KRPIVLTVFVAH +YS-NLENANKIIAEIARLAFLD- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5YB64_9BACT +-kKLESRVEGTASRLDGVMGVAILDLTDGRIL-LRNADRVFPAASSIKIAILLELYRQDQ +KGKARLDGIYTFDPKDLVEDSRIMAGLTAGVITNRDLAQFMVAVSDNAAANVLYDRV-GR +DNVNAMLHSLGLSKMMLRRKMMDIAAARRG-DENVATPREMVRLLEAIYKEKALNKQATA +EFITQLSTLKQ--SYIPRSLPDNVQVANKPGELD-AVRNDSGIVYALNR-PFAISVMTAY +DR-DEKAAERAISEVALEAYHYf +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8G4G2_9BACT +------------------------------------------MASVYKLPIALELLAQVS +QGALTLDRQVPILASDIRACCTLSRRHPNGGLSAGELLELMIVESDNTAADAVLKLVGGP +PVVERRLRALGFDAINVNRYEGDIAFRYTRDPRDTATPDDMARFLARLQLGNLLPRAPTD +LLLDLMARAKTGPHRIKALLPPDTSVAHKTGTTDV-VINDVGIVTLPTGGHLVLAAFAMN +GG-RVTAMQKTIAQLAGAAFECf +>[subseq from] Serine hydrolase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A426H0P4_9BACI +-qTIEHDILALVESFNGKIAYKIED-GLGETI-GYHVNESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPNEVTGGSGVLHALSNKVLTVEDLLTLMITVSDNTSTNMMMSLL-GI +DEINRCIKELGLKNTILERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE +RIMRVFDNQQI-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQA-VYAAVLTED +M-KSEEESRQVISKIGKLIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus cavernae TaxID=1674310 RepID=A0A3S0TYA1_9BACI +--ALNDSIKQLLEPFDGRIAFKIEM--DDQMI-EQKSEDIFPSASLIKIPILIETFRQSE +ERQIYLNQPVTIPLQERVGGSGVIHAMSDKVMTIEDILTLMIVVSDNTATNLLISLL-GQ +DQINGCLKELGMDKTVLNRKMMDSK-AIEEGRDNYTTAADVLASLKAINEGTLLTAESKQ +RILTIMKKQQF-TDKLPARMDEKVSVANKTGSLP-GVTHDCAIITYGEKT-AYAAVLTDG +LS-SEEEGRQMIAKIGELVYEY- +>[subseq from] serine hydrolase n=1 Tax=Senegalimassilia anaerobia TaxID=1473216 RepID=UPI0013896BEF +---LRDALEQAVEAHSGAYAVTCASADGSWSV-DVNGDKPFVSASIIKLAILGTLLDQAQ +SGVLSLDGTVTVSPSDIVGGTGVIQASGAGEYTYRQLAAYMIQDSDNVATNLIIDAV-GM +PAVNEYASEIGLTQTVLNRRMMDFAA----GDENYTSANDVARMLQLIYQGKLVSPDMSE +FALDLLKGQHD-DAGLLEGLPVGSVFAHKTGTLD-GVFNDGGIVLD--QNPYVMVVLSSD +AERSQ--AQACMVDIAQAA---- +>[subseq from] serine hydrolase n=1 Tax=Oceanobacillus sp. YIM 98839 TaxID=2663380 RepID=UPI0013DCAC76 +-nQLKVDIQAIIEDSGGEWGIAIEDLHTNEIF-TEQADRPFYAASIIKIPIMITVFKRYE +DGAFTLSDKLSLKREDMVGGSGVLQHMTPGTLTIYDLLMLMIIQSDNTATNMLIDLV-GT +KEIQQTLDTIGAFNSKFYNKLMIVPVQ--KEGSNIITANDMTLLLKQLVNGQIISVHACQ +QMINIMKKQQI-RESLPGKLPKKWELAHKTGNVTK-VRHDVGIFYVGNRT-LIASVLSQG +MN--DLVSKELFHDIGLAIFN-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A270AFY5_9BACI +--TIEHDILALVEAFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPSGEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE +KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKLIYD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI000BA4EF6F +--TIEHDILALVEAFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPSGEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE +KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKLIYD-- +>[subseq from] serine hydrolase n=1 Tax=Senegalimassilia anaerobia TaxID=1473216 RepID=UPI0009DA0AC2 +---LRDALEQAVEAHSGAYAVTCASADGSWSV-DVNGDKPFVSASIIKLAILGTLLDQAQ +SGVLSLDGTVTVSPSDIVGGTGVIQASGAGEYTYRQLAAYMIQDSDNVATNLIIDAV-GM +PAVNEYASEIGLTQTVLNRRMMDFAA----GDENYTSANDVARMLQLIYQGKLVSPDMSE +FALDLLKGQHD-DAGLLEGLPVGSVFAHKTGTLD-GVFNDGGIVLD--QNPYVMVVLSSD +AERSQ--AQACMVDIAQAA---- +>[subseq from] serine hydrolase n=1 Tax=Leptolyngbyaceae cyanobacterium CCMR0082 TaxID=2304604 RepID=UPI0013D2ABD0 +---LKTKLEELQELIELTPTIYVFDLDTGNYV-EVAGNAETPAASTIKLPILIAFFKAVD +EGRITVDQALAMQSNQIAGGSGDMQGQPPGTYTALEVATQMIINSDNTATNMMIDLLGGP +QALNQQFADWGLTMTILRNPLPDIEGT------NTTSAQDLVRMIAHLHKGDILSLRSRD +RVMNILQRTYN-KKLLPAGVSETTISYNKTGNIGE-VLGDVALMDLANGKRYAIAALVRR +PEND-GRAQELIRRISQAVYQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A1N6W851_9BACI +-qTIEHDILALIESFKGKIAYKIEN-GHGDMI-GYRENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKQLGLKNTILERKMQDFK-ALKEGLDNTISAEDTITCLKAIHTGNFLTKESQE +KILRVFDNQQL-RDKLPSLMGKGVKVASKTGGIR-GVSHDCAIIRSETQT-VYAAVLTEG +MK-SEEESRQVISKIGKLIYD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. B4EP4a TaxID=2590665 RepID=UPI001154CEA9 +--TIEHVILALIETFNGKIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESQE +RILRVFDNQQL-RDKLPSLMGKGVKVASKTGGIR-GVSHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKLIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis X23 TaxID=1200792 RepID=A0A291BHU9_BREBE +---LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINEVQRFYAASAIKVPIMTAVFAEAY +AGKFALEDKIKLRAEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNIMIDLV-GT +ESIRNAMQKTEMTNSHFYNKLMVIPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL +KMVAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG +LE--QKDAADVMAQIGNLVYHVy +>[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A413HDX0_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGDNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNEPQASQFVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A537J774_9BACT +-qNLKQQIIEQLSQPKGTFAVAFKDISSKKEL-IINEKEIFHAASTMKTPVMIEVFRQAS +KKKFSLNDSLVLKNESIVDSSSFAYKHLGEKRSIYDLVYQMIVVSSNLATNLIIEKV-DA +SNVTQTMRRYGANDIQVLRGVEDQK-AYDKGLNNTTTAYDLMLIFEKIARGKAVNKKACE +AMIDILLDQKF-NTIIPAQLPKDVKVAHKTGFIT-GIHHDSGIVFLPDGRKYVLVLLSKN +VE-DEDKAVKTMANVSGMIYQY- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A354PGU9_9PLAN +--RLAELIQPLIDAHDGKIGLAIKHLGNGNGF-VYRADDPMPTASLIKMAVMVTAYDQIH +AGTLSRTLPIALKEQDKVPGSGILTAHFSEGLSLRDAIRLMMAYSDNTATNLVVDQI-SL +PATATLMKSLNLPNTQLHSKVYRRDTSIDLERSGSTTAAETIAMLEWIDRGQIINREICD +EMLEHLYANQD-SSKLARSLPAKVRVAHKSGDVN-ASRCDAGLVDGPQGR-IAICVLTDE +NASDNNAALKLMGEIAAVTYRHy +>[subseq from] Beta-lactamase n=1 Tax=Bacillus asahii TaxID=228899 RepID=A0A3T0KP35_9BACI +-qSIEPKILELIETFDGRIAYKIEN-DRGESI-SYHEHEAFQSASLIKIPMIIEGYRQAE +NQDIYLNQPLTIPRNEVTRGSGVLHTLSDKVLTVEDLLTLMITISDNTSTNMMMTLL-TF +EKINQCIQELGLENTVLERRMFDFKA-LKEGRDNTMSAADTVLCLKAIHTGNFLTKASQE +RILDIFEQQQF-KERLPAMMGKGVKVGNKTGSLR-GVMHDAAIIRSETET--VYASVLTE +DMASEEESRQIISKIGKLIYDE- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. vincentii TaxID=155615 RepID=A0A2G7H8V4_FUSNV +-tEWKKEIEKIISQVEGSVCINFYDLNKNNVF-SINGDKKVLSASMIKLLILAELMKKNS +ENKFSLSDTVMMANFMKIGGDGVLKELNTGHFTLKELATLMIIISDNQATNILIDFL-GM +ENINQLGKELDLKETFLGRKMMDAEA-RKKGYDNYTCADDISLLLKLIYQEKLINKEASQ +LILDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGDRA-YILVVLTNG +MP--NLQCKQTIGKISKFIYDK- +>[subseq from] Beta-lactamase n=1 Tax=Fibrobacter intestinalis TaxID=28122 RepID=A0A1T4NA50_9BACT +-qSLTDTLSKIASEYPGEIGVAAI-INNSDTI-AVHDKPVYPMMSVFKVHQALALCNVFD +RQNFSLDSSITIQREELDPWSPMLKEHPEPELTVKNLLRYTLTQSDNNASNLLFQKFVDV +SQTDSFIASIPRASFQIAFTEKEMSANHDKAYANYTSPLGAAMLMNRLFNDSLVSREKQN +FITNTLQECTTGKDRIVAPLKEGVVIAHKTGSGYTNAHNDIAYIQLPNDIHYSLAVFVKD +IQGNETLAAEAISRLSASVYAY- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2W0A368_9BACT +-tKLQEKIAAVDRNLDGVMGVAVRDLTNSETY-LLHGDDVFPQASSIKIAVLAELYDQEQ +RGRARLADLYTVRSEDLVPDSFIMGGLTPGVITNRDLATMMVAVSDNSATNVLIDHL-GM +PNVERMLASIGLKNTHLQRKMMDIAAA-RQGRENVSTPREMMTLFDAIYRNKLFDKELTA +DFFKVLSTPK--DSSIPKLLPADLNIANKPGELE-AVRNDSGIIFVPNR-PFILCVMTTY +LH-DERVGQRSISEIALAAYEYf +>[subseq from] serine hydrolase n=1 Tax=Chitinophagaceae bacterium PMP191F TaxID=1691979 RepID=UPI0006BC04FD +---IQEEITNLLQQQQGIFAVAFKDLSSGKTI-LINEHEVFHAASTMKTPVMIEVYKQAA +EGKFSMDDSLELKNSSIVDGSTYQYGQLGKKSTIAALVYDMIIVSSNLATNMLIEKT-GA +PNVMQTMRQLGANDIQVLRGVEDTK-AYEQGLNNTTTAYDLMIIFEKMAKEEIVNKQASK +QMINILLNQQF-NDIIPAMLPKNVSVAHKTGNIT-GVQHDSGIVLLPDGRKYVLVLLSKQ +LT-DTAAAIKVMANISAILYR-- +>[subseq from] Beta-lactamase n=2 Tax=Sphingomonadales TaxID=204457 RepID=A0A2E0Q6C5_9SPHN +---FERQLASLADGSAGRIGVYAIDLNTGEEV-GVLEDQRFPMASTSKVAIAATFLAGVD +QGRWSLSSEFELPG-------------RGTYISAGEHLNLMITRSCNDCTDALLNAVGGP +QAVNKWMRQAGIYDFELTRNIASLVRASQIAFEDSATPRAMGKLLAGIYQGQWLTPYSRR +VLLEAMGGTVTGKRRMSSALPMSANLAHKTGTLSR-TASDIGIFQTPDGHMVAAAIYVTG +QSVSMEVEN-------------- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. PCC 7003 TaxID=374981 RepID=A0A1B1TT58_9SYNE +-----TTQAAIAADPNLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFLEAVD +SGKVQLDDSLTLTKEVIGGGSGSMQYTPGSTYTALYTAREMSVNSDNTATNMITELLGGN +AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARINQGEILSVRSRD +RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER +PYND-PKGKELLHKISRQFYDH- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI00105D43B0 +----LARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRIE +QGDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +ERVNAVTRELVPEGFGPITTLTDVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] serine hydrolase n=1 Tax=Bryobacterales bacterium KBS 96 TaxID=639034 RepID=UPI000372583E +-qKLEHGVETLDSGLDGVMGVAILDLTTGREW-MYHANEVFPTASTIKLAVLTELYHQQE +TGAAKLTDMYTVRKEDLAPDSAILDNLTPGVLTNRDLAAAVVAVSDNSASNILTNRL-GM +ARINTMLDGLNLKQTRMRRLMMDLEAA-KQGRENVATPHELVLLLQAIYQNKLFRPELTQ +DLLNLLSTPKS--SSIPRLLPEDLKIANKPGELF-GVRCDAGIVFVPKH-PFAIAIMTTY +DR-DGRAAEQTISQVALLAWRLf +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=uncultured Eubacterium sp. TaxID=165185 RepID=A0A1C5RMA9_9FIRM +-----EKLIAYLQREGVSGAFAVKDLRSGEIC-SFNEDEVVASASLIKMFILIRAFQKIR +AGEMTLDDQIEVRAEDVVDFSVLLFLDP-RKYSLRELLKLMIVYSDNTATNVLIDLF-GM +DGINSTIRELGYSDSVLQRKMMDFRAA-EEGRQNFTSVKEMLDLMERLYEDRLLGSPYDG +QMLDIMKGQAD-ETMMRQELPDELVIARKSGELD-ALDHDIAIVYTEKGN--YIYIFFAW +DAKDNNHARKILSETSKLVFDDf +>[subseq from] Uncharacterized protein n=1 Tax=candidate division KSB1 bacterium TaxID=2172550 RepID=A0A3A0D121_9BACT +heKTEAKLWEIAGNVSGVMGIAALDLTSGERF-GVNENMVFPQGSAIKIPVLMEVYKQAT +EGKFRLTDLRWIDKQHKVGGSGILQQLGDHTLSIRDLAILMIVLSDNTATNMLIDLV-GM +ENVNRTMSSLGLTQTRLQRRMINAAAS-GKGEENLSTPSEAVRIMEVLHRGEFLNRQVCD +EILEILKKPKSG--GLNAGLPANLPVAFKPGGIP-GVSTEWAIVYLKER-PYAVAVMENY +EM--NGEAKSAMKEISRILYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Melainabacteria bacterium GWF2_32_7 TaxID=1801605 RepID=A0A1F6PM50_9BACT +--RLTNRLKYLAKQYSLEPGIFIWDFSTGQYV-DINADQEFPTASIVKIPILLQLFRRAE +LGFANLNDRMSLAEYNITGGSGYLQYKPVGTFPIHHLARLMXXXSDNTATNMILSTVGGT +NELNRVLRSWGFSKTHMSDLLPDLYGT------NVSTPKDMGTMLFNLDNSDFLTLKSRA +AIVDIMSHVRN-RFLIQAGLPDNAQFIHKSGDIGT-MLGDAGIVMLPDGRKYIIVIMVKR +PW-NLYSAKEFIINASKITYNSy +>[subseq from] Beta-lactamase class A n=2 Tax=Pedobacter ruber TaxID=990371 RepID=A0A1G9LU15_9SPHI +---LKKKINAEFAKNKGIFAMAFKNLSTGEEI-LINEKIHFHAASTMKTPVLIEAYKQAA +AGKFSIEDPLTIKNESIVDGSPFSYTKTGTQVKIYDLLYLMIIKSSNLATNLIIDLV-GA +KNANNTMREMGANDIQVLRGVEDTKA-FRKGLNNTTTAYDQMLIFSEMADGKIVNQESSD +AMINILLDQKF-NDKIPAKLPKDVKVAHKTGWIT-GVNHDAGIVFLPDGRKYVLVFLSKE +LT-DDQAAVKSMAKVSRMIFNYf +>[subseq from] Class A beta-lactamase n=1 Tax=Barnesiella sp. WM24 TaxID=2558278 RepID=A0A4Y9J114_9BACT +-sQIEERLKTYVAAQDTRIGVAVI-IDGKDTI-SVNGNRDFPMLSVYKFPQALAVADYCM +KKGITLSDTIGIQAKEIKEWSPMRNKYGVSDLPLSEILEYSLQQSDNNACDVLFRLIGGS +QVSDSLMKASGYGDITIGSTEDEMHRDPYLCYQNRATPIAMARLFDKFYRLEMHDSPVHE +AVGAMMMLCGTGDNRLPAPLATDAVIAHKTGTGGRNGINDAGYVFLPNGRGYAIAVFIAD +SAYDMARTEKIIADISKIVYQ-- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. polymorphum TaxID=76857 RepID=A0A1Z3CIR3_FUSNP +-tEWKKEIEKIISQVEGKVCVNFYDLNKNNGF-SINGDKKVLSASMIKLLILAELMKKIS +EDKFSLSDTIMMANFMKTGGDGVLKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] serine hydrolase n=1 Tax=Ammoniphilus sp. YIM 78166 TaxID=1644106 RepID=UPI00106F0B9B +--QLVDQVKQQIESAGGEWGVVLEDLQTGEEY-RWNAEERFYAASVIKLHIMVAVFGAAN +EGKFNLSDTLVLRREDITTGAGVLQHMTPGTLSIYDVITLMIIQSDNTATNMLIDLV-GK +KRIRDVIKELELNNTTFYNKLQVVP--YPLKGSNQTTAGDTALLLKRLVTQKVISWHACE +QMIDIMKKQQL-NDFLPSNYPKSWEFAHKTGMVTR-IHHDAGVLYRNGRA-LLVSFFSRG +LE--TKEAREAMSHIGQAIYEY- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001104F167 +-nSVQQQLEALEKSSGGRFGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDRTEPT------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. An51A TaxID=1965640 RepID=A0A1Y3XGV6_9BACE +---LTDSISRIVSACPGEVGVALI-VNNSDTV-TVNNKSIYPMMSVFKLHQALAICNRFD +QDGLSLDTSLTVRREDLDPWSPMLKEHREPLLPVRDLLRYTLIQSDNNASNLLFERLVSV +AETDSFIATIPRSSFRIAYTESEMAADHAKAYANCTSPLGAAMLIHRLFTDALVSREKQD +FIMKSLGECTTGKDRIAAPLKEGISIAHKTGSGYTEAHNDVAYICLPNGVNYALAVFIKD +FKGNESQASQVAARISAAVY--- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Pseudomonas TaxID=2583993 RepID=A0A350N2V5_PSESP +----LARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRIE +QGDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +ERVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGARRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A165NVG8_PSEST +----LARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRIE +QGDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +EQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Rufibacter sp. DG31D TaxID=1379910 RepID=A0A0H4VU76_9BACT +-nSLKEQITTELSKQKGTFAVAFKDLKTGEEL-LINEHTSFHAASTMKTPVLLEAYKQAA +EGKFSITDSILVKNESIVDGSLYSHRLLGQKRTLYDLLYRMIIQSSNLATNIVIEKL-DA +KNVTQTMRSLGMKDMQVLRGVEDTK-AYRQGLNNTATAYDLMVLFQHIAQGKAVSKKASQ +EMVKILLDQKF-KDIIPSKLPTDVKVAHKTGWIT-GVRHDSGIVFLPDGRQYVLVLLSKE +LQ-DEPAGIAAMATVSEMIYKH- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7MCA2_9BACT +--SLRARIEARIAQAPARVGLYYRDLSGGDSL-TVGAAARFHAASTMKIPVMIQLFRDQD +AGLLSLDDSVTVTNTSIVDSSPYQYKRLGQRASIRELIELMETVSSNLATNLLITRV-DA +KRANATAHALGADSILVLRGVEDGK-AYRAGLNNTTTARDLGMLLAAIANGKAASAASCR +AMLAILGRQHF-TEGIPAGLPPGTRVYHKTGWIGQVVYHDAAVVEPTDGRRYVLVVLTGG +IQKD-EDSHALVRDLSRLVFD-- +>[subseq from] Serine hydrolase n=1 Tax=Pleurocapsa sp. CCALA 161 TaxID=2107688 RepID=A0A2T1CIH1_9CYAN +---LKSQLEQLATQYDIKPELLFIDLDNKGFV-SIDSKLPLPAASTIKLPILVAFFQDVD +RGKINLAEEFIMTKDVIAGGSGGMQYEPPNSFSALKTAEQMMTNSDNTATNMLIKRLGGM +EQLNQRFTKMGLTATKLHNPLPDLTGT------NTTSSADLGNLLVKIDGGSLISLRSRD +RMLYIMRNIVR-NTLLPEGLEPGALIAHKTGDIKS-VLGDVGIIDMPNGKRYIASILVKR +PDN-SPLAKEFIQKASGVAYQYf +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sp. SYSU K30005 TaxID=2666135 RepID=UPI0012D97B5B +----EQMIQEMIKETPYNAHLFVKNLKTNQLLiDYQLESSFSSASVIKVPILLALLTYME +NNNISLDSTRSISPDDWVDFSVISELRLTQ-STLYELLVWMIITSDNTATNVCIDVV-GM +EFLNDYFRQIGLQDTVLQRKMMDVER-LAKGIDNRTSARDMAHLFTRIYQQDVLSPSYSK +LVIDILSRQRV-HDSLMRYLVDDVKLAHKTGGLDT-VDHDVGIVYSSAID-YSIGVFLTN +VT-DNDQARQLIGRLSKVVYDQ- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides ovatus SD CMC 3f TaxID=702443 RepID=D4W9A8_BACOV +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGDNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] Beta-lactamase class A n=1 Tax=Lysinibacillus acetophenoni TaxID=614649 RepID=A0A285U3R2_9BACI +-----EKIRSLIECVDFKVHLFVKEAKSENYIlNEKSDDIFSSASLIKVPILLGVLDYLE +KNNQTLDEELPIAIENKVEFSVVTEQNLDS-CTLYELLVWMIITSDNSATNVLIDFI-GM +EELNIYFNKIGLTQTRLQRKMMDFKS-LNKGYDNVTTARDMAYLFSRVYQQDLLSDQYSQ +LVIDILCRQRV-HEGLKRYITDDIFIAHKTGSLDT-VCHDVGIVYHPSNN-YIIGIFLTE +LA-DVEIGKRLIGRISKIVYEYf +>[subseq from] serine hydrolase n=1 Tax=Emticicia oligotrophica TaxID=312279 RepID=UPI00025F5AAF +----------------MNVSMVVEEMNGNKIY-EYRPSVKMPSASVIKIPILMTLMGKVA +KKELSLEDTHTLLHEEKTGGSGVLAEMSDGKFTIRELAQEMIRSSDNTATNILINKV-GR +ESVNAYLQQWGMSQTRLNRVMMDTEA-VKQGRENYINAREVNALLQMIYGHKIATPALCD +EMLEMLKNCAD-KSTIPSQLPQNLSIAHKTGTLAY-VRGDAAIVFTQN--PFVISIFVEG +FDK-ESTAEKVIGDLAKICWN-- +>[subseq from] Beta-lactamase n=1 Tax=Terrabacteria group bacterium ANGP1 TaxID=2569760 RepID=A0A537K9E4_9BACT +------------------MGVYVRAVATGEEV-ELNADRPFQMASVFKIPILAELLSETH +AGRRPLDNRIILTDQMKAPGSGVLKELSAGTLTVRDLATLMIIVSDNTATDILLGLV-TK +EAVNSRLRACGLERTTVAMSCRELLWVYRDERANTTTPREMAVLLGHVLRPTLLAPDVCR +QMLDILRRQQI-RDRLPLLLAPAVDIAHKTGSVSR-VSNDAGILYAPKS-PCVVTVFTRD +LAD-DLKGRMAIAQVGQAVYEAy +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. V59.32b TaxID=1758642 RepID=A0A3E2J5H1_9BACI +--ALEESIMQLKNHADGRIGLHIEI--DGKVI-ESDGQEIFQSASLIKIPILIEAFRQSE +EKRIYLNQPVTIPMTERVGGSGVIYALTDKVMTIGDIITLMIIVSDNTATNLLISFL-GQ +DEINRCIKDLGLDKTVLNRRMMDFE-AINQGRDNLTTATDMLVCLKAIKEETFLSSKSNE +QILSIMRKQQM-TDKLPALMPEKVSVANKTGSLP-GIVHDCAIITYGEKT-AYVAVLTSV +SS--EEEGRQVLAKIGKLVYEY- +>[subseq from] serine hydrolase n=1 Tax=Luteimonas abyssi TaxID=1247514 RepID=UPI000737D495 +---LRERLEAADRRFAGDIGVFVQHLGSGEAF-SFHADEPWYLASGIKVVVAIAVLQRVE +AGDLSLETRVRLRETDFVDGAGQTNSWPAGTLRVSYLLEQMIVYSDNTATDVLIRTV-GE +DEVNVLARALGLTITTLADVR----RAYYATNVNAASLRDYARMLEALAEGRALGTEQTR +YLLDVMTRVRTGDRRIKAALPAGARFAHKTGTQYR-RVCDLGIVTVRGANEQVVVAACAR +GA-PTAAGERALRDVGAAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium ljungdahlii TaxID=1538 RepID=A0A162L2T3_9CLOT +------KILAAIDLKKLNCSFVIENLKTGEKI-AYNENMVVPSASLIKIPIMMEILNQVK +EGKLSLKQRITVEDNVKVPFSILNLLETGNSYTLKDVITLMIIQSDNTAANILMDLA-GM +DNVNNYIKNLKIKNTVLQRKMMDSKAR-KEGRENKTTAADMAKFFEIIYKGEKAEESYSI +LMKDILTNQLD-NSVMRLSIPDDTVIAHKTGDLY-GISHDAGIVYLPNVD-YIFCGLTWD +AV-TNNFARETIGKISKIAYDYf +>[subseq from] Beta-lactamase n=2 Tax=Rubrobacter xylanophilus TaxID=49319 RepID=Q1AVA6_RUBXD +-----EEAAGVVREHPGVAGFYVRDLKSGAGY-GVRPDQVFFSASTIKVPVMIAVYRRID +QGRLHYSDRIVTTEEDWAAGAGWLRWQTPGASTVEDALWLMIAQSDNVATNALVRLVGGP +GYVNEVARSLGAEDTALHWKLSSERAAVP-SLDNRTTPRDMALLLAKIRSGEAASRYACR +EMLGLLEQNNL-EWWIEGGVPPGVKVANKGGWLDS-TYNDAGIVEYEER-PYVLAVFTEY +GP-GLGEGGRYLQRISRAVW--- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus sp. CFH S0501 TaxID=1644114 RepID=UPI00106E2C9E +--TLHDSIMSLVEKAGGKWGFVIEDLQTNERL-AYQEDERFYAASLIKVPIMTAVFAEQY +AGKLSFEDKVRLKKEDLVGGSGVLEQLTPGTFTIYDLVMLMIIQSDNTATNMLIDLV-GK +KSIRSIMKKTGMSNSQFHNKLMVIPAELEG--YNEVTAADMANHFRLMATGKILSYNSCL +QMIRILKQQQI-QQSLPLHLPPRWEMAHKTGSVST-NDHDVGILYVGQKA-ILISTLSAN +VPA--NLARDTMGRICELVYQLy +>[subseq from] Uncharacterized protein n=1 Tax=Synergistetes bacterium HGW-Synergistetes-2 TaxID=2013843 RepID=A0A2N1QPP8_9BACT +-----QKIYELLGGLEGKAALYVEDLASGEIF-TICADEVHVACSLVKVPILALLLKDAE +EGGARLEEKISIPPEKRVGGTGLICHEPEAELSWRDVMKLMVIVSDNSATNAVIDLL-GI +DRINAFFKSIGLTSTELQRKMMDME-AIKAGRNNYTTAADMGRLLKLAATGSLVSRNVSD +AVIDTMSRQLY-TSKLPALLPASVTVANKTGDLPK-TEHDVGLFILPGGKRYVVAMLTSQ +LA-SEKEGIACIAKVSKIIYDA- +>[subseq from] Beta-lactamase n=2 Tax=Lunatimonas lonarensis TaxID=1232681 RepID=R7ZPI9_9BACT +-------------------------IQEREVLsVHDPARRIPSASIIKVPILIALMQDVQ +EGKRSLSEEIVLHESDMVAGAGELQFRAPGTYSLEFLAREMIRISDNTATNLLIQTL-GM +DRIQGWLQSHGFRQTQLNRLMMDFG-AIEAGRQNYTSAEEMVRMLLELADGKYLDAKGTD +FVLELLRDCAD-REAIPSKLPAGTVVAHKTGTLDY-VRGDAGLVWG--EKPLAICVFVEG +FS-SLEQADEIIGQIALLAFDTy +>[subseq from] Uncharacterized protein n=1 Tax=Acidimicrobiaceae bacterium TaxID=2024894 RepID=A0A2E5P4B3_9ACTN +-----KDLTSFAKTFTGVLGVSAVHLETGEQV-AYNSDHPLLTASTFKSILLVSLLEMVD +VQKLSLDDRITFTATKRVAGSGVLKLMRSDTVSIGDLAVLMITISDNTASQMLFDVV-GH +DRIQHTIDRLGLTRTRIPLSPKEMLLRAYSSEGNISTPADMCRLFRRIHNNEVLSCESKR +TFLDIHKGQQL-RTVIPHRLPAGTVCAHKTGQFEL-VSCDVGIVYSRHG-PYAIALMANG +ARGDRIEVNAALAALSRRVFDEf +>[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus odysseyi 34hs-1 = NBRC 100172 TaxID=1220589 RepID=A0A0A3INB9_9BACI +-----RMIEQLLQTCPYKVHLFVKDAKAKGYFhSLLIDEVFSSASLIKVPILIAVLDHVE +RHERSLDEVIQIQSENRVDFSVITEQQLNE-STLYELLVWMIITSDNTATNVLIDYL-GM +DALNTYFGKIGLTHTTLQRKMMDFVR-LESGFDNVTTARDMAHLFTRIYRQDLLSVPFST +LAIDILSRQRV-HESLTRYLVEDIHIAHKTGGLDS-VDHDVGIVFNHVN-DYIIGVFVTE +VTN-NDEARQFIGRLSKAVYEQ- +>[subseq from] Beta-lactamase n=2 Tax=Prevotella TaxID=838 RepID=A0A3R6AR46_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGDNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] Beta-lactamase class A n=1 Tax=Larkinella sp. BK230 TaxID=2512173 RepID=A0A4R8CZB3_9BACT +---LRQQIEQELGKQPGTFAVAFRDLQTGQEL-LIREHENFHAASTMKTPVMIEVYKQAA +QGRFSLSDPILVKNSSIVDGSLYSYTKVGTKRPLSDLVYDMIIVSSNLATNLVIELV-DA +RKVTQTMRDFGARDIQVRRGVEDKK-AFEQGLNNTTTAYDLMVIFDKIATGKAVSPEASK +AMIRILLDQRF-NTVIPAQLPTDVQVAHKTGSIA-GVHHDSGIVMLPDGRKYVLVLLGKD +LK-DDAAAIKSMATVSRLIYEY- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFOXYA2_FULL_40_6 TaxID=1797958 RepID=A0A1F9X070_9BACT +-nDLNKEVMENVYSFPGEVGLYIKDLKTGVVI-TYNENKPFASASLVKLPIMAATYQAIE +DGNITLQEQLTLTRSLKAAGSGTLKMRRGTKFCVSELLYHMITESDNTATNMISNKL-GY +GYINWVFKNLNMEVTRMDRGIMDLRMR-KYGVENYTTAREMGDILEKIYNKQLISERASD +EMLTILSQQKH-KDRIRRFLPKNLNVANKTGLLRD-ICHDAGIVFTDKGD-FIVCVLTSD +FGPSYRVAKNLIGEVAYKTYRC- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=UPI0005196F2A +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGDNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Niastella yeongjuensis TaxID=354355 RepID=A0A1V9FC05_9BACT +--KLKDQISSKLAEQPGNFAVAFKDLSTGEML-LLNDQDFFHAASTMKTPVMIEVYKQAA +AGRFSLNDSFALKNSSIVDNSAFSYQHLGEKYSLYNLVYDMIIRSSNLATNMVIELV-NA +HNVTQTMRQLGADKIQVLRGVEDSK-AFDKGLNNVTTANDLLVIYEKMAQGEIVDNASSQ +AMIKILLNQEF-NDIIPARLPKDVKVAHKTGNISH-VLHDSGIVFLPNGKKYVLVILSKN +LQN-EANAKKAMAEVSEMIYNY- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. animalis TaxID=76859 RepID=A0A0M4RIX7_FUSNU +-tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGDKKVLSASMIKLLILAELMKKVF +ENKFSLSDAITVTEAMKTGGDGVLKELNSGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELRLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQEKLINKKASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILAVLTNG +MP--NFQCKQTIGKISKFVYDK- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9BHP6_9BACT +---ARGEIEKRIQASGADVAIAFRTLDGKLEW-HVRADEPFHAASTMKVPVMIELFSQVK +EGKARLDEPLVVRNESIVDGSAYSYKAAGQTRTLEQLCEAMISVSSNLATNLLIEKL-GV +ENIQKTVGALHAEGMNVLRGVEDE-KAYEKGLNNTTTARGLEVLLEAIAEGKAVDGEASR +QMVEILERQKW-NEAIPAGLPPGTAVAHKTGEITK-IHHDAAIVYAK--RPFVLVILVRG +MA-DSKASAALMADITRALFQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. Soil768D1 TaxID=1736405 RepID=A0A0Q9VJ99_9BACI +-qTIEHEILALVETFDGRIAYKIEN-ADGDTI-SYHDDEPFQSASLIKIPMIIEGYRQSE +EKKIYLNQPVTIPPIEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMTLL-GH +DEINQCIKELGLKNTILGRRMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE +KILRAFDNQQL-RDKLPSLMGKGVKVASKTGAIR-GVAHDCAIIRSEFQT--VYAVVLTE +DMKSEDESRQVISKIGKLIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6KZU0_9BACT +-kKLETRVEEIASSLDGVMGVAILDLTGGRIL-LRNADRVFPAASSIKIAILLELYRQDQ +KGKAKLDDIYTFDPKDLVEDSRIMAGLTAGVITNRDLAQFLVAVSDNAAANVLYDRV-GK +DNVNAMLHSLGLPKTLLRRKMMDIAAARRG-DENIATPQEMVRLLEAIFKEKALDKQATA +EFIKQLSTLKQ--SYLPRYVPESVQVANKPGELE-GVRNDSGIVFAQNQ-PFAISVMTAY +DR-DEKAAERAIGEVALEAYRYf +>[subseq from] serine hydrolase n=1 Tax=Ornithinibacillus scapharcae TaxID=1147159 RepID=UPI000225AB98 +--ELTDRIEEITNEAGGTWGIALYDMDTGISW-EKNSHDTFYAASVIKVPIMIAAFAASQ +KGELSLSEQLELKREDIVGGSGVLQHLTPGYFSIYDLITLMIIQSDNTATNMLINYI-GV +AEIQQSMREIGMEKSRFCHRLMTLEVD--REGQNEINAYEMTEMLVKLASGKIISAHASE +QMITIMKKQQI-RNALPSNIPKKWEFANKTGNIP-GISHDIGMLYVGNR-IFIASVLSKG +VE-D-IEAPKIIGNIGLEIYQY- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A3R8VHA0_PSEST +----LARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRIE +QDDLTLDSRVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +DQVNAVTRELVTEGFGPITTLADVRRRYYVTPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGARRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] Serine hydrolase n=1 Tax=Terrabacteria group bacterium ANGP1 TaxID=2569760 RepID=A0A537LUQ1_9BACT +---LQGVVEGAAARVSGRLGCCVCP-ETGTPWaIHRAEETFATASVIKAPIAVAVAAEVE +AGRLEWNQLLPPHLRDDAGDSGVIRHLSPLPYTVRDLVFLMLVVSDNRATNLLIDLV-GM +ERLNASFARAGWKHTSLARRLGDFEAR-ARGLENRSTPRETCDVFLRLLRGDLLSPGSRT +LLLEFLKAQVY-RDRLPARLPRTTAVAHKTGDMP-GVENDAGVLYLPAG-PIVAAVFTNE +LA-SDVEGRLAIQEIGRAIYD-- +>[subseq from] serine hydrolase n=1 Tax=Varibaculum timonense TaxID=1964383 RepID=UPI0009BB80F3 +--SLEKAIFSTLSELDGTIGMYFEDIVTGKKI-CINSEIEFSAASTIKIPLVLLLLTQAK +AGLIDLEEQIEIDKANRIGGSGVIKEISSSYPTIMDLAKLAIILSDNIATNQLVDIVGGV +KKVTEFCKSIGMDSTKFQRKMMDFES-LKLGKDNVTTPRDMGRLLKMLAEDDNRLSGVSS +KMIDIMKAQQL-NQKLPNLIPALVVVAHKTGELWR-AQHDVGIFILPGGHKYILALYTSD +LSS-DSKGVEVIAKLSKIVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Phormidium tenue NIES-30 TaxID=549789 RepID=A0A1U7J3W1_9CYAN +---LKGELEQLATLTPGTPVGFAVDLDSGQYV-DLGGAEPVASASTIKVPILVAFLQQVD +AGTLALNQSMALQEEYMANGSGTLREAVGTEYTALEIATRMIVTSDNTATNMMIASLGGI +EALNQTFAAWGLEHTVLRNALPDLDGT------NTTSAKDLTLLMALIDQGGLLTPRSRD +RLFSIMQRTEN-GSLIPSGIRDGSLLANKTGDIS-AMLGDVALVDVPNGKRYALAVLVQR +PAND-GRASELIRRMTETI---- +>[subseq from] Beta-lactamase n=1 Tax=Spirosoma radiotolerans TaxID=1379870 RepID=A0A0E4A0Y8_9BACT +--QLRKQIEQELSKQPGVFAVAFRDLATGNEL-LVRERDVFHAASTMKTPVMIEVYKQAA +QHKLALSDSLTIKTESIVDGSTYSYKAIGTKRTLEALVYDMIIVSSNLATNMVIERV-GA +QNVTQTMRDLGAKDIQVRRGVEDSKA-FAQGLNNTVTAYDLMVIFEKIAIGKAVNPQASN +AMIKTLLDQKF-NDAIPGKLPRDVKVAHKTGSIA-GVRHDSGIVFLPDGRKYVLVLLSKD +IK-DDKATVATMATVSELIYTY- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044E1E4D +------------------------------------------------------------ +-----------------------LEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] serine hydrolase n=2 Tax=Escherichia coli TaxID=562 RepID=UPI0013A5BBCE +------------------------------------------------------------ +-------------------------------------------------ANLLLTTIGGP +KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDSTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. An19 TaxID=1965580 RepID=A0A1Y4JNU6_9BACE +---LTDSISRIVSACPGEVGVALI-VNNSDTV-TVNNKSIYPMMSVFKLHQVLAICNRFD +QDGLSLDTSLTVRREDLDPWSPMLKEHREPLLPVRDLLRYTLIQSDNNASNLLFERLVSV +AETDSFIATIPRSSFRIAYTESEMAADHAKAYANCTSPLGAAMLIHRLFTDALVSREKQD +FIMKSLGECTTGKDRIAAPLKEGISIAHKTGSGYTEAHNDVAYICLPNGVNYALAVFIKD +FKGNESQASQVAARISAAVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Acidovorax avenae subsp. avenae TaxID=80870 RepID=A0A2R4F2L8_9BURK +--PLERALARVEADSGVRIGVHVRDLDTGAFA-SLHGTEPWYLASSVKVPVAIAVLRGVE +RGDFTLETPLTLRAADYVDGAGPTNSRPVGTLTVRYLLEQMIIYSDNTATDMLIGLV-GI +GTVNAVVQSLVPRGFGRITSLADVRRTYYATGLNSGHLDAYADLLQTLVEGRALDARHTA +YLLSVMERVKTGTQRIKAGLPPGARFAHKTGTQR-ARTCDSGLVTVPRSGPRLLVVACTR +GEPSTARSDRALRQVGIALC--- +>[subseq from] serine hydrolase n=1 Tax=Acidaminococcus timonensis TaxID=1871002 RepID=UPI0008DA9961 +----------------GPFQIYFTNLSTNQSI--YRGSETMPAASMIKVFILAKAYEDIQ +SGSLRRNETFTLTPDNVVGGAGILQGRGYGTVSLQEAMDLMITESDNTAANLLIDRL-GM +DRINSYMQSHGYTHSVLRRKMMDTEA-MREGRENMTSTRDIALLFKRLYRGQCVGPAQDR +EMLEIYKRQTD-NDSIPGALPKGTVVAHKTGEVSD-FRHDGGIVYTPKGD-YVLVIFTGN +YTPY-ETMAD------------- +>[subseq from] Uncharacterized protein n=2 Tax=Senegalimassilia anaerobia TaxID=1473216 RepID=A0A369L8W6_9ACTN +---LRDALEQAVEAHSGAYAVTCASADGSWSV-DVNGDKPFVSASIIKLAILGTLLDQAQ +SGVLSLDGTVTVSPSDIVGGTGVIQASGAGEYTYRQLAAYMIQDSDNVATNLIIDAV-GM +PAVNEYASEIGLTQTVLNRRMMDFAA----GDENYTSANDVARMLQLIYQGKLVSPDMSE +FALDLLKGQHD-DAGLLEGLPAGSVFAHKTGTLD-GVFNDGGIVLD--QNPYAIVMLSGD +AERS--QAQACMVDIAQAA---- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI001143025C +----ENQIQDLIQKTPYKVHLFVKDPKTDQFLfSHQLEESFSSASIIKVPILLAVLAYTG +KHNISLHSSLTITPTDWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM +DFLNDYFRQIGLQETLLQRKMMDVER-LAMGIDNFTSARDMAHLFTRIYQQDLLASPYNE +LVIDILSRQRV-YEGLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYGSSFD-YLIGIFITN +VT-DNDLARQLIGRLSKVVYDH- +>[subseq from] Uncharacterized protein n=1 Tax=Olsenella sp. oral taxon 809 str. F0356 TaxID=661087 RepID=G5F2U5_9ACTN +---IQAAVEAALAGHSGSAYVAYESVDGSTTGfSLGGEERVPSASMIKTAVMATLLQEAQ +DGRISLADGTILRGQDRVEGSGVVQDMRAGTLSYGQLAAYMIGQSDNMATNLLIDAL-GM +DAVNEECQRLGLADTSLRRKMMDTAAATS-GRENYTSASDQARLLLMVARGELVSPEASE +RALGWLEDQAD-TRGLAQGLPDGVAFAHKTGSLD-GVRHDGGIVLG--DHPYVFVVMTTG +MD--QGQADALMARVSTAVWE-- +>[subseq from] Uncharacterized protein n=3 Tax=unclassified Gemmatimonadetes TaxID=234665 RepID=A0A1Q7TIJ0_9BACT +---LKARVQARILQTPARVGLYYRDLTTGDSL-TVGSDVRFHAASTMKVPVMIQLFRDRD +AGLLSLDDSVTITNTSIVDSSPYRYKRLGQWASIRQLIELMETVSSNLATNLLIAKV-DA +KRANATAHALGADSILVLRGVEDD-KAYRAGLNNTTTARDLGMLLAAIANGKAASAASCR +EMLAILGRQQF-NEGIPAGLPPGTTVYHKTGWIGQVVYHDAALVEPPNGGRYVLVVLTGA +IQKD-ADAHAAVRDLSKLVFD-- +>[subseq from] Serine hydrolase n=1 Tax=Lewinella nigricans DSM 23189 = NBRC 102662 TaxID=1122177 RepID=A0A2D0N8R0_9BACT +--DLEQQVKEEFDQGDGTFAMAFMDLTTGDQL-LINARESFHAASTMKTPVLIELYKQSE +AGKFSLEDSILVKNESIVDSSLYSYDVVGSKRTVADLAYDMIIVSSNLATNLVIDLV-DA +RKVTQTMRDLGAPDIQVLRGVEDIK-AYELGMSNSTTAYDLMAIYEKLGRGEVVSPEASE +AMIDILLDQKF-NDIIPAHLPEAVKVAHKTGSIT-GVHHDSGIVMLPDGRKYVLVLLSKE +LG-DFAAGTELLAGVSKMVYDY- +>[subseq from] serine hydrolase n=1 Tax=Pygmaiobacter massiliensis TaxID=1917873 RepID=UPI000C79DEAF +---LKNEIESYLATRPGKVAVVWRDLISGGDF-SIAGKTRFVSASTIKLLIMAELLDQIA +AGRRSLSDHILLTQARVTGGDGILKERPGHSFALEEILTLMIIVSDNTATNLLIDLL-GM +DAINAQARKLRLREAQLGRKMMDTEAK-RQGRENYICAEDMAKMLELIYRGTLVDEKMSR +TALEILLRQQQ-TGRLQLYLPEEIPVAHKCGDLDC-LEHDGGLILVEGH-PYLLVVLTEQ +NP-SNREGRETIGTISKMVYDA- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7XDV2_9BACT +---------------GRDVGLVLLPLDGRDAV-MVEPDKTFHAASTMKVPVMIELFRQAE +EGKLRLEDPLPIVNESIVDGSVYHYKAVGKTMTLRELCEAMITVSSNLAANLLIERV-GV +ENIRATVARLGATGMDVRRGVEDQK-AFDQGLNNTTTARGLAVLMQKRAKGQAVSPRADA +EMVAVLKRQKF-NDAIPAGVPEATPIAHKTGTITK-IHHDAAIVYGP--RPFVLVILVRG +IQE-QKESAALMAAISREVWN-- +>[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T181_9BACT +-tALQNELTDFVKDKDARIGMAVI-IDGKDTV-AVNGKEDFPMLSVYKLPIALALADNYR +VKGLDFSEPIAIAKEDLHLYSPMTGRLLASSMPTREILNYMLQQSDNNASDLAVKKLGGT +ENVMKWLSKSGLSGVKVVSTENEMHINPELSYKNSSTPIAMARLLDKLDTE--WNDSLSK +EIKQMMETCKTGENRLAKLLPTNAVTGHKTGTGFIMAVNDVGYVHLSNGHRYSIAVFIAD +AHYDMAESENIIAQISEMVWR-- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=UPI0004D3B9EB +----ENQIQDLIQKTPYKVHLFVKDPKTEQFLfSHQLEESFSSASIIKVPILLAVLAYTE +KHNISLHSALTITPADWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM +DFLNDYFCQIGLQETLLQRKMMDVER-LAMGIDNFTSARDMAHLFTRIYQQDLLASPYNE +LVIDILSRQRV-HEGLKRYLVDDVKLAHKTGGLDT-VDHDAGIVYSSSFD-YLIGVFITN +VT-DNDLARQLIGRLSKVVYDY- +>[subseq from] Serine hydrolase n=2 Tax=Halomonas sp. 1513 TaxID=1883416 RepID=A0A1P8R451_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +-RVTAFAERLGVAREELKLDTDAAFDAYEASALNGGTLVAFGELLATLARGGGLSAASRE +ALLAVMRRTRSGEARLKAGFGDDVVYAHKTGTQHR-RTCDAGIAQRGGQRQVAVVACTRG +P-LDVVPHERLLAEVGAAI---- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5VKA8_9BACT +-kKLETRVEEIAARLDGVMGVAILDLTDGQVL-LRNADRVFPAASSIKLAILLELYRQDQ +QGKAKLDDIYAFDPKDLVEDSQIMAGLTPGVVTNRDLAQFMVAVSDNAAANILYDRV-GR +DNVNALLRGLGLSKTTLRRKMMDIAAARRG-DENVATPQEMIRLLEAIYKEKALNKQSTA +EFIKQLSTLK--DSYIPRYLPEGVQIANKPGELE-GVRTDSGIVFAPNR-PFAISVMTAY +DRDEKA----------------- +>[subseq from] FRAMP1.1 beta-lactamase n=1 Tax=Prevotella sp. CAG:1058 TaxID=1262918 RepID=R5CN93_9BACT +-qTAEEAITRLARGRQATVGAAWIS--GGREH-AVNNRGDYPLMSVFKTHCAIAALRRMQ +REGIPADTLIRVKAAEMTPYSPLAKMHEGEDMRFDSLLYYSIALSDNNACDVTIRMAGGI +EGVNAEMEAIGLAGCALTETEATMAADPQRSYNNRSTPLSVAVLFRKLYEDGILGGDYDR +LMKAALEATQTGPDKMKAALAPGMTLAHKTGTGFMTADNDAGAVTLPDGRRIYIAVLVKD +TRLGTKENARLIREITEAIIR-- +>[subseq from] Serine hydrolase n=1 Tax=Niastella populi TaxID=550983 RepID=A0A1V9G892_9BACT +-nKLKNQVNSKLAEQPGDFAVAFKDLTTGDSL-FINEQTFFHAASTMKTPVMIEVYKQAA +AGIFSLNDSFTIKNESIVDSSSFRYRHLGEKRTLYELVYDMIISSSNLATNMVIELV-NA +RNVTQTMRQLGADRIQVLRGVEDSK-AFDKGFNNITTANDLLVIFEKMAKGEIVDSTACQ +AMIDILLKQQF-NEVIPARLPKDVKVAHKTGNISH-VYHDSGIVFLPDGRKYVLVLLSKN +LK-NEEQAKKAMAEVSELIYKY- +>[subseq from] Serine hydrolase n=1 Tax=Litorilinea aerophila TaxID=1204385 RepID=A0A540VDX5_9CHLR +---LLHNIQAAVAASGAHMGIAIHHLESGETL-ELNADEPFPLCSVLKIPVLVEAFRQLR +EGRFRLDDRWELTLAEKNLPSGVLVFLQDGLPTVQDLLTLMIIISDNTATDMLMHRL-GV +ARINQTMHELGLADTHIALTIREIFDFSTGPDNDVGTPRDMTRLLTLIFRGEVVDREACD +QMLHILLQQQL-NTRLPLFLPEGVPFAHKTGTLS-GIRNDAGILYASPTSHVAISVFSRW +DARRTTAIDEAFGRIGRLVYDHy +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. FJAT-22090 TaxID=1581038 RepID=UPI0011A8FC58 +-kKLVSRIQDLIERSEGIWGIVLEDLELDERW-ELNGEELFYAASVIKVPIMVAVFSAAE +KGEFKLSDQLLLKEEECVGGSGVLQHLTPGTLSIQDIVMLMIIQSDNTATNILIDLV-GV +EAIAQTMKEAGMEKSTFYNKLML--STPPPKGYNQITPNDVAKLLKSLTTGTLVSPHASE +QMIDIMKKQQM-NECLPEKLPSVWELSHKTGWIP-GTRHDVGIFFVEGRK-LIATVLSKD +ED--DLLSKGILNEIGEEIYNY- +>[subseq from] Serine hydrolase n=1 Tax=Acidovorax avenae subsp. avenae TaxID=80870 RepID=A0A2R4EHP4_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +QRVQTLARTLQVRKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ +MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAHAIVVATCAE +GMDEMRQAGRLFEQIGRAITR-- +>[subseq from] Beta-lactamase n=1 Tax=Fusobacterium nucleatum subsp. animalis D11 TaxID=556264 RepID=D6BHN0_FUSNU +-tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGNKKVLSASMIKLLILAELVKKVS +ENKFSLSDAITVTEAMKTGGDGVLKELNSEHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINQLGKELRLKETFLGRKMMDIEAR-KNGYDNYTCADDISSLLKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLLSDIKIAHKCGDLDN-LENDGGIIWLGNKA-YILVILTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7804A9 +----LARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRVE +QDDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +DQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A2D8IFF2_PSESP +----LARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRIE +QGDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +ERVNAVTRELVPEGFGPITPLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGARRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] Beta-lactamase n=2 Tax=Firmicutes TaxID=1239 RepID=A0A0A3J0I7_9BACI +----KEELERLIDSVDYNIHLFIKRAKAEDFIfAKQLDEVVSSASLIKVPILIAVLELIE +RQNISLQMEVEIKQNHKVEYSVLTEQDSD-KSTLYELLVWMIITSDNTATNVLIDFL-GM +EECNAFFKKIGLTRTKLQRKMMDFDS-LQKGVDNVTTARDMANLFTRIYKQDLLPLQFSQ +LALDILSRQRI-NDGLKRYIIENVKIAHKTGNLDT-VSHDVGIVFHEKLD-YIIGIMITD +IN-DAEEAKKCIGLISKIVFQYf +>[subseq from] serine hydrolase n=1 Tax=Spirosoma radiotolerans TaxID=1379870 RepID=UPI0009E4E25D +--QLRKQIEQELSKQPGVFAVAFRDLATGNEL-LVRERDVFHAASTMKTPVMIEVYKQAA +QHKLALSDSLTIKTESIVDGSTYSYKAIGTKRTLEALVYDMIIVSSNLATNMVIERV-GA +QNVTQTMRDLGAKDIQVRRGVEDSKA-FAQGLNNTVTAYDLMVIFEKIAIGKAVNPQASN +AMIKTLLDQKF-NDAIPGKLPRDVKVAHKTGSIA-GVRHDSGIVFLPDGRKYVLVLLSKD +IK-DDKATVATMATVSELIYTY- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5T5C8_9BACT +-kKLETRVEEIASSLDGVMGVAILDLTGGRIL-LRNADRVFPAASSIKIAILLELYRQDQ +KGKARLDDLCTFDPKDLVEDSRIMAGLTAGVITNRDLAQFLVAVSDNAAANVLYDRV-GK +DNVNTMLHGLGLSKTMLRRKMMDIVAAQRG-DENVATPQEMVRLLEAIFKEKALDKQSTA +ELIRQLSTKK--DSYIPRYLPESVQVANKPGELE-GVRTDSGIVYAQKR-PFAISLMTAY +DR-DERAAERAISEVALEAYRYf +>[subseq from] Beta-lactamase class A n=1 Tax=candidate division TM6 bacterium GW2011_GWF2_33_332 TaxID=1619080 RepID=A0A0G0CP64_9BACT +--DIQKKVQEICTSVPGEMGVAALHIESGRRV-EFNSHEAFPMASSYKIPIALSCLSLVD +SGRLSLNQHVLF-----VGRSKKTPNVKKVYVTLRKCIELMLARSNNTTSDRVLEMTGGP +FAVNSWLSRHQIYGMRIDRPVLKMRKKFYVDERDTTTPRVMVDLLAQAFEGKLVSERSTS +FLFSCMAKCCTGSMRMVHLLPKHVKVYHKTGTMD-GIISDVGVITLPGGGHLVLAVYSNK +SMRLTDDRALAIARIARSLFDYf +>[subseq from] Serine hydrolase n=1 Tax=Larkinella rosea TaxID=2025312 RepID=A0A3P1C1N4_9BACT +-eQLKQQIELEFKKQPGRFAVAFKDLTTGNEL-LIREQEVFHAASTMKTPVMVEVYKQVA +QKRFSLTDSILIKNQSIVDGSLYSYTEVGKKRTLYSIMYDMIIVSSNLATNLIIDLV-DA +RKVTQTMRELGIKNSNVLRGVEDTK-AFQKGLNNTVTAYDLMILFEKIATGKAVSPQASE +AMIKVLLDQHF-SSVIPAKLPKDVKVAHKSGSFAT-VRHDSGIVYLPDGRQYVIVLLSKE +MP-DDAAATETLATVSGLIYQY- +>[subseq from] Transpeptidase domain-containing protein n=1 Tax=Bryobacterales bacterium TaxID=2026791 RepID=A0A359LPX7_9BACT +--TLDERVRAAVTGFQGTVSLYAKNLATGAEY-GLRADERVRTASTIKLPIMAAVFAAVE +RGQARWDERIKMTREDKVSGSGVIRELADDSLTLRDLVHLMIVVSDNTATNLVLDRF-TA +DFVNEELDRLELRQTRSLRKILGDGREFRRFGIGVSTPREMARLLEKLHRGEAVSAGASK +EMMAILKRQQY-KDGIGRRIEEE-KVASKSGALD-ALRSDVGIVETARG-PVALAITVDG +MPSPENAGNKLIGRLAELIVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_64_13 TaxID=1797948 RepID=A0A1F9UWP7_9BACT +--ELNRKVREQSERFPGVSGIVIKDLRRGWTI-EHNPSRLFPSASLVKLPLMVALYEADL +RGEISLDQSFPILRHLRARGSGTLKQRPGTRLTIHEFISRMITESDNTATNVLTNLF-GL +DYYNSQFLSMGLSRTNFSRTIMDLRQR-DRGIENYTTPRDMARLLEWIYRGRF---SGSR +EMMDILKAQKI-NDRLARGIPGDWTIGHKTGLMRD-SCHDVGIVFAPGSD-YVICALTTD +AR-SSRRAKKFITSLSKLTAEYy +>[subseq from] Beta-lactamase enzyme family n=1 Tax=Rubrobacter radiotolerans TaxID=42256 RepID=A0A023X3Z3_9ACTN +--------VEVVERYPGIVGFYALDLRDGSGF-GVRPDEEFFSASTIKVAVMAAVYRKID +AGELEYSDELTTTDEDWAAGAGWLRWTPGAKATVEDALWLMMTESDNVATNVLTRAVGGP +EYVNEVIRDLGAKDTELFWKLTSERAAVP-ELDNNTTPRDMTTLLSGIYNGEGFKDFSRR +EMVDLMGQNNL-EYWLEGGLPPEVKAANKGGWLD-GSYNDVGIVRYEES-PYALAIYTMN +GP-VIEEGQGVLSEVSEAVW--- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. X1(2014) TaxID=1565991 RepID=A0A077JB23_9BACI +---LKEKITKDLVDFKGRVGVAIEI--EYERY-EFHSGEVFPSASVIKVPILIECLKQSE +LGKIDLDEFIKIT--DRAGGSGVLQALSTNLLTIKDLMTLMITVSDNTATNMLINIV-GM +DQINQTMEEIGLHSTRLQRKMMDFAAK-EKGLDNVTSPSDMVKCLKIIHEEDFLSANSRR +MALDILHFQQFHDKLLAMINTDKVFTANKTGSLSN-VENDCAIIKAGSKT-AYVAVLTDQ +LP-DPYEARQVISRIGKHIYN-- +>[subseq from] Serine hydrolase n=2 Tax=Pseudomonas TaxID=286 RepID=A0A6A9R223_PSEST +----LARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRIE +QGDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GV +DQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGARRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A414XI42_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGENGAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] Beta-lactamase class A n=1 Tax=Caloramator quimbayensis TaxID=1147123 RepID=A0A1T4WDN7_9CLOT +------NIRGIMEKHDIKYSLIVKNLSTGEML-NINGDTSIPSASTIKVFIMAEAFRQAK +EGKISLKERIKVDKSYHVPYSIISLLSEDNTYTIMDLITLMIIQSDNTSTNVLIDIL-GM +GKINDYIKSLGCSLTVLERKMMDFIAR-DKGLENKTCARDLTLFMELLYKGEVVDESSSK +IMMDILKHQLD-TSMMAYFIPEEVSIAHKTGEVSR-VDHDFGIVFLDNLD-YIFTMMTYD +VK-SNNDARFAIAQVSKEVYDYf +>[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A127STN6_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGDNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A3R6DLM7_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGNNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] serine hydrolase n=1 Tax=Anaerosphaera massiliensis TaxID=2040296 RepID=UPI00126012C3 +-eNLKGKIINMLSKRSGNISITFYDLDEKEGF-SIRGDKKAPSASMIKLLIMIEVMRRVN +NRELFLNEKYKINEDMKVGGSGILKDLEDGHFSLRELIILMIIVSDNVATNFLISLV-GM +DNINTTGKNIGLKNTILERVMMDIDAT-REGRDNYTSSDDVALIFNKIYNQELISEELSQ +IMLGILLKQQY-RDRLQRYLPEDIKIANKSGDLDY-LENDGGIFFRKNK-NYILVVLVNS +AI-SNYEAKESIGRISEIIYEE- +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=A0A1E4R5Z3_9BACI +----ENQIQHLIQKTPYKVHLFVKNPKTEQFLfSHQIEESFSSASIIKVPILLAVLAYIE +KHNISLHSSLTIAPADWVDFSVLREQRMT-QSTLYELLVWMIITSDNTATNVLIDVV-GM +EFLNDYFRQIGLKETMLQRKMMDVER-LAMGVDNFTSARDMAHLFTRIYQQDLLASPYNG +LVIDILSRQRA-HEGLKRYLVDDIKLAHKTGGLDT-VDHDVGIVYSSSVD-YMIGVFITN +VTEN-DLARQLIGRLSKVVYDH- +>[subseq from] Serine hydrolase n=1 Tax=Acidovorax avenae subsp. avenae TaxID=80870 RepID=A0A2R4DUV7_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +QRVQTLARTLQVRKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPSHQQ +MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAHAIVVATCAE +GMDEMRQAGRLFEQIGRAITR-- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. AWRP TaxID=2212991 RepID=A0A3T0LVN8_9CLOT +------KILAAIDLKKLNCAFVIENLKTGEKI-AYNENIVVPSASLIKIPIMMEILNQVK +EGKLSLKQRITVEDNVKVPFSILNLLESGNSYTLKDVITLMIIQSDNTAANILMDLA-GM +DNVNNYVKNLEIKNTVLQRKMMDSQAR-KEGRENRTTAADMAKFFEIIYKGEKIKESYSV +IMKNILTAQLD-NSVMRLNIPDDTLIAHKTGDLD-GISHDAGIVYLPNAD-YIFCGLTWD +AV-TNNFARETIGKISKIAYDYf +>[subseq from] Serine hydrolase n=2 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534GPQ1_9GAMM +------AIESTIKKSGADVAVAFRTLDGRTQW-LRRPDEPFHAASTMKVAVLIELYRQAR +QGKLKLDDPLSVKNESLVDGSAFAYRAGG-GRTLRELSELMITVSSNLAANLLMDRL-GV +ENIRAGVHALGADGMNVLRDLEDAKA-FEHGLVNTTTAQALLALLEAIARGQAVDRESSR +QMLETLERQTI-NDGIPAGLPAGTRVAHKTGDITR-IWHDAGIVLAS--RPFVLVVLTRG +LEN-PKESTALIAEITRELYR-- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A229I6J2_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGGNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Bathyarchaeota archaeon TaxID=2026714 RepID=A0A2E8EI86_9ARCH +-eKLLRRLEAITNDFNGVMGISIKDLVSGDEF-NINENEVFPVASSIKIPLLMEFFRQVK +SGMLDLYSEITIQEGNKTKGSGVLNELGDGTMSLQDLATLMIIVSDNTATNMLIDKV-GM +DDVNLLMQNLGLMETKLQRKMQDYQAALSG-QENISTPFEFMKLMECLFRKKGLDAWVCE +QTLSVLKKPKI--TAISLGVPMELEIANKPGGMI-GVSCDAAIIFQPNR-PYVIIILTKE +ISLSDARAGKRITEVSSLVYEYf +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. NIES-970 TaxID=1827144 RepID=UPI000BBA56C9 +--------AAIASEPTLDASLLFVDLDTGEYL-DVAGDRALSAASTIKIPILVAFLEAVD +KGEVNLDDTLTMTQEVIGGGSGGMQKTPGSTYSALYTATEMSVNSDNTATNMIIEVLGGN +TALNAKFQQWGMAQTQVNNPLPDLEGT------NLTSAKDLAHLLARINQGEILSMRSRD +RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGT-IIGDAGIIDLPNGKRYVAAIFVER +PYND-PKGRELLHKISRQFYDH- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. NKBG15041c TaxID=1407650 RepID=UPI0011DD353A +--------AAIASEPTLDASLLFVDLDTGEYL-DVAGDRALSAASTIKIPILVAFLEAVD +KGEVNLDDTLTMTQEVIGGGSGGMQKTPGSTYSALYTATEMSVNSDNTATNMIIEVLGGN +TALNAKFQQWGMAQTQVNNPLPDLEGT------NLTSAKDLAHLLARINQGEILSMRSRD +RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGT-IIGDAGIIDLPNGKRYVAAIFVER +PYND-PKGRELLHKISRQFYDH- +>[subseq from] Class A beta-lactamase n=1 Tax=Nocardia panacis TaxID=2340916 RepID=A0A3A4KWJ9_9NOCA +------------------------------------------------------------ +-------------------------------MTLLEIAAAAVTRSDNAAGNLLLRELGGP +QRFTAFLRSLGDQAARLDDNEPALGAFRPGDDRNTTTPAGLAADYRAVTLGAVLGTPERV +QLIQWMREAKTGDSRIRAGLPSDWITADKTGTGGYGCVNDAAITWPANGAPLVIAIQACG +NGENGAADETLFPEVTRLVLD-- +>[subseq from] ClassA_beta_lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X5A8_9BACT +-----------------------------------------PMLSTVKFPIALAILYKVE +QGELAMKQKLLIKKAHLREWSPFRKLHPNGNITLEEAMTWMVAESDNNLTDVLLRLIGGT +ETVKEFMDS---EGFIIKNNEADMHKDWAAQFVNKIRPTVAVQVLQEFDQQRILNPQHTK +WLYTTMAGSKTGDKRLKGKLPENIVVAQKTGTSFTGAINDIGIIELPGNKKIYIAVYVRD +CAEPFETGEAIIADIAKVTYDYy +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax citrulli (strain AAC00-1) TaxID=397945 RepID=A1TIK7_ACIAC +--PLERALARAEADSGVRIGVHVRDLETGASA-SLHGTEPWYLASSIKVPVAIAVLRGAE +RGDFTLDTPLTLRAADYVDGAGPTNGRPGTPLTVRYLLEQMIIYSDNTASDMLIGLV-GI +GTVNAVVQSLVPRGFGRITTLADVRRSYYATGLNSGRLDAYADLLQALVEGRALDARHTA +YLLSVMERVKTGPQRIKAGLPPGARFAHKTGTQR-ARTCDSGLVTVPRAERRVLVVACTR +GEPSTARSDRALRQVGIALC--- +>[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium M5B4 TaxID=2054928 RepID=A0A2N5JQL6_9CYAN +---------------ELNLHLMVYEPDQGGYV-DINAATPTASASLIKLPLLVAFLEQLD +LQTIALDEMLQLTEGDKAPEAGILQDQPGTKISALEVATLMITESDNTATNMMIKRLGGI +EVINERLDKWGMKQTRFRNILPDLQGT------NTTSAKELVELFSKVEQQQLLSLRSRD +LFMDILSQTKN-NSLIAEPIGEKSRIRHKTGTIAN-LIGDVAMIDAPNGRRYFLAVMVRR +PPED-PSAEELIRKISATVYSHf +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=UPI001290C3BC +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPHSSFQIAYTEEEMSADPDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGNNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNEPQASQFVAHISAVVYS-- +>[subseq from] Uncharacterized protein n=2 Tax=Bacillus TaxID=1386 RepID=A0A127D529_9BACI +-qTIEHDILALVESFNGKIAYKIEN-GLGETI-GYHVNESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPNEVTGGSGVLHALSNKVLTVEDLLTLMITVSDNTSTNMMMSLL-GI +DEINRCIKELGLKNTILERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE +RIMRVFDNQQI-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +M-KSEEESRQVISKIGKLIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Cytophagales bacterium TaxID=2053541 RepID=A0A521GJF0_9BACT +-----DSLTAYIRSLTVRVSVALESLASSERF-YYRADERVPSASLIKVPIMVAAMTAAQ +AGKLDLDEIHILTDSEKVGGAGILQTYPNRSISYTELVRLMITISDNTATNILISDL-GR +EAINTQMQSWGMTQSRLNRVMMDTLAA-RQGRENYVTAREMNQLLTKIHEHKLLTPALCE +QMLTFLKQNED-TLTIPHLLPPQVVVAHKTGVLAY-VRGDAGIVFAP--RPFVLTVLVEN +AG-TEAAGEQTIADLAFLVWK-- +>[subseq from] serine hydrolase n=1 Tax=Luteimonas sp. LNNU 24178 TaxID=2605430 RepID=UPI0011EFC41C +---LRTRIEAADARFPGEIGVYVHHLGRDESF-SFRAEESWYLASGIKVPVAIAVLRRVE +RGELRLGDRVRLRADDFVDGAPTNAQRVGTPLRVDWLLEKMLVYSDNTATDVLIRSV-GV +DAVNAVATELLATDDLLITTLADVRRAYYETNVNAAPLRDFGHMLATLSDGLALGPEGTA +YLLDLMSRVKTGAKRIKAGLPPNAVFAHKTGTQHR-RACDLGIVTMPDGVERVVVAACAR +GAASNAASERALREVGVAVT--- +>[subseq from] Beta-lactamase n=1 Tax=Hyalangium minutum TaxID=394096 RepID=A0A085WKX8_9DELT +--------QRIIQVKGASVAVVYQDLGDLKDSvLIEADRSFHAASTMKVPVMVEFFRQVD +AGTLSLDQPIPLVNQSIVDGSPYAYEQLGKSVPARELIQRMITRSSNLATNSVIALV-DA +KRATQTLRTLGAQQMTVLRGVEDGK-AYQQGLNNTATAKDLATLLAAIERGKAASDRSTE +AMRSILLAQEL-NEEIPAGLPPSTRVAHKTGQIS-GVLHDAAIIYPSGRAPYVLVVLTSG +IP-DEKVARSLIVDISRAVYAH- +>[subseq from] Beta-lactamase class A n=2 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=A0A370FRT6_9BURK +--RMASAMQQLGGASQTGIGVYVLDLASGQSF-GHRADERWYLASMVKVPVAIAVLQAVE +RGEISLDTTVTFRAGDRVDGAGATLRQPLGSLSVRWLMGQMIIYSDNTATDMLIDLV-GL +QAVNGVAQTLAPRGIARITPLAEVRRAYYAEGLNSGRLDAYAQILVALAEGRALGAEATQ +TLLKLMEDVATGPQRLRAGLPPQARFAHKTGTQRR-RICDAGLVRMPARHPVVLAACVRD +AP-SLGRAEHLLAQTAAALC--- +>[subseq from] serine hydrolase n=1 Tax=Halomonas sp. BC1 TaxID=1670448 RepID=UPI0009BC907E +------------------------------------------------------------ +------------------------------------------------------------ +----ALARTLGVSSSSFAQDYDSAFDAYEASGENVGTLRAYGDLLASLHHGGMLDREQRQ +TLLEVMQRTRSGTQRLKRGMGREVTFAHKTGTQHR-RSCDAGIATRDGAQHWVIVACSRG +PL-ALSAHEQALTRVGEALHD-- +>[subseq from] Serine hydrolase n=1 Tax=Fibrisoma montanum TaxID=2305895 RepID=A0A418M338_9BACT +--------------TKARVSLAVESLADSTPSfYHHADERVPSASLIKLPILIEAMERIK +AGQLDPDEIHILTDSEKTGGDGVLKTYSHRSIAYRDLIRLMMIHSDNTATNILINEL-SQ +NAINQRIRSLGLSATQLNRVMMDTVAA-RQGRENYVTAREMNHLLKRMYHHQLATPALCD +QMLDILRQNED-RQTIPRLLPKTVAVAHKTGILSY-VRGDVGIIYAS--QPFVLSVLVQG +VP--TAEAERIISEIALMCYNQy +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3M2EAQ0_9BACT +-----------------------RDPHTNTRY-DFHAERLFHAASTMKVPVMIEVYRQAE +AGRFSLDDSLLVRNESIVDGSAYRYRMLGRRMAIRDLVHRMITVSSNLATNLLIDLV-TA +DSVQATAERLGVRHMQVRRGVEDLLA-FRQGLNNTATAADLAVLLDALRRGAAVSPEADR +TMIDVLLDQQF-GDLIPAGLPPGVRVAHKTGAITR-IHHDAAIVYPERGPAYVLVVLTEG +VE-DQARSAELVAEVARVVHE-- +>[subseq from] Serine hydrolase n=1 Tax=Ignavibacteria bacterium CG2_30_36_16 TaxID=1805221 RepID=A0A1J5FXT8_9BACT +-eKLTAEIKNKLDSAKGIYGLVYKDLQTGENI-FYNEKENFHAASTMKTPVMIEVFKQAE +EGSFSLDDSILVKNESIVDSSLYMYQFIGGKKTIRQLVYDMITVSSNLATNILIDLV-HA +ENVMRTMKEIGAENIKVLRGVEDIK-AFEKDLNNTTDAFDLMLIFEKIAIGEIISEKACS +EMIDILLNQEF-NSRIPALLPSDVKVAHKTGSIT-GIEHDGGIVILPDGRKYILIILSKG +IQGS-KLKTNIQAEVSRMIYDYf +>[subseq from] Serine hydrolase n=1 Tax=Variovorax guangxiensis TaxID=1775474 RepID=A0A502DZ80_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +QRVEALRNAMKVGKEDLKAKSDEAYDRYYQRNLNSATLVAYGTMLEKLVQGKLLKPDSTQ +KLFTAMKVDIFTNYRLQAGLPRSVKFIHKTGTQHR-RACHSGVINPQNGGDAIVVVTCAA +DLDEQREAGKVFERVGRAITK-- +>[subseq from] DUF3471 domain-containing protein n=1 Tax=Sphingobacterium olei TaxID=2571155 RepID=A0A4U0P445_9SPHI +---LKSRIQKLAKQPEGRFAYAFMDLQTGEQL-SLNAHELFHAASTMKTPVMVETFKQAA +EGKFSLSDSITVYNQSIVDKSKFSYVRVGTKITRHDLIFRMITESSNLATNIVIDQV-GA +KNVMKTMKSIGANDIQVLRGVEDTKA-FQKGMNNQVTAYDLMLIFERIAKGTMVNTEASK +AMIDILKKQKF-NSVIPAQLPKDVQVAHKTGSIA-GIFHDSGIVYLPNGRAYVLVLLSAD +VKD--NAVKKTLANVSLQFYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora coxensis TaxID=356852 RepID=A0A1C5JAU3_9ACTN +----------------NQAGATVRDLSGMQQV-AVNGTLRPKAASVIKLWILVELLRRVD +CGQVSLDERVLVTQADVVGGTGQLQEQIPQLATLRKLAEYMIEYSDNTATNVLINYLGGF +APMNALADSMNQRQTVLARKMLDTEAA-ARGEENYTSPDDVISLLGAVWDAQILTPASRD +LMIGFMREQTL-NSKIPAALPPGTPVAHKTGELPD-ASHDVGYYLIPGA-ETAVAFLTSG +PE---PSGADLVRRLARTVYDY- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora coxensis TaxID=356852 RepID=UPI000B5AC25C +----------------NQAGATVRDLSGMQQV-AVNGTLRPKAASVIKLWILVELLRRVD +CGQVSLDERVLVTQADVVGGTGQLQEQIPQLATLRKLAEYMIEYSDNTATNVLINYLGGF +APMNALADSMNQRQTVLARKMLDTEAA-ARGEENYTSPDDVISLLGAVWDAQILTPASRD +LMIGFMREQTL-NSKIPAALPPGTPVAHKTGELPD-ASHDVGYYLIPGA-ETAVAFLTSG +PE---PSGADLVRRLARTVYDY- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000DA55527 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLD------------------------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534ESA6_9GAMM +------AIESTIKKSGADVAVAFRTLDGRTQW-LRRPDEPFHAASTMKVAVLIELYRQAR +QGKLKLDDPLSVKNESLVDGSAFAYRAGG-GRTLRELSELMITVSSNLAANLLMDRL-GV +ENIRAGVRALGADGMNVLRDLEDAKA-FEQGLVNTTTAQALLTLLEAIARGQAVDRESSR +QMLETLERQTI-NDGIPAGLPAGTRVAHKTGDITR-IWHDAGIVLAS--RPFVLVVLTRG +LEN-PKESTALIAGITRELYR-- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A6A7VS45_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPHSSFQIAYTEEEMSADPDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGNNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNEPQASQFVAHISAVVYS-- +>[subseq from] Beta-lactamase, putative n=1 Tax=Synechococcus sp. NIES-970 TaxID=1827144 RepID=A0A1Q2TXL1_9SYNE +--------AAIASEPTLDASLLFVDLDTGEYL-DVAGDRALSAASTIKIPILVAFLEAVD +KGEVNLDDTLTMTQEVIGGGSGGMQKTPGSTYSALYTATEMSVNSDNTATNMIIEVLGGN +TALNAKFQQWGMAQTQVNNPLPDLEGT------NLTSAKDLAHLLARINQGEILSMRSRD +RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGT-IIGDAGIIDLPNGKRYVAAIFVER +PYND-PKGRELLHKISRQFYDH- +>[subseq from] Beta-lactamase n=2 Tax=Archangium violaceum TaxID=83451 RepID=A0A084SPU3_9DELT +--------ERIAQVKGATVAVAYRHLGNSKESlYLEADRSFHAASTMKVPVMIEFFRQVD +ADKLSVSQELTLANQSIVDGSPYAYERLGKPVPARELVERMITRSSNLATNTVIALV-DA +KRVTKMLRSLGARQMTVLRGVEDGK-AYQKGLNNTATARDLATLMTAIEQGKAASPASTQ +AMRSILLAQEL-NLEIPAGLPPGTPVAHKTGQIS-GVLHDAAIVYPSGKTPYVLVVLTSG +IP-DEKVARSLIADLSRQVFA-- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A646FR36_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPHSSFQIAYTEEEMSADPDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGNNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNEPQASQFVAHISAVVYS-- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Limnothrix TaxID=2632864 RepID=A0A1C0VBK0_9CYAN +--SLSDQFQKIAARYSLILHAAALDLDTGDFA-AWNDNRSVAAASTIKVPILVAFFQDVD +AGKIRLDEMLTMEARFVAPEAGTMQQKPGQKFSAIDTARQMIVISDNTATNMIMARTGGS +GPLNQRFQSWGLQGTSIRDLLPDITGL------NRTTARDLVQLTALINRGELVSMRSRD +RLLSIMRGTAA-NSLLPKGIGKGGEVAHKTGTLAK-LLADTGLVDTPNGRRYGIAVLAER +APND-PKAAEAIRDYSRAAYNHf +>[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3M4U0_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +KRVQALARALDDADTFQVRTMDEAYDRYYQQRFNTATLTGYGAMLENLVRGKLITPQHQQ +ALFKDLKFDTYDAYRLEAGLPRSVRFIHKTGTQLH-RACHMGVIEPQDGKSAIVVAACAE +GLDEQKEAGKAFEAVGRAITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. AM23-5 TaxID=2292054 RepID=A0A415VCF2_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGSNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044E2A66 +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKN-- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=UPI0009DC0EB4 +--RMASAMQQLGGASQTGIGVYVLDLASGQSF-GHRADERWYLASMVKVPVAIAVLQAVE +RGEISLDTTVTFRAGDRVDGAGATLRQPLGSLSVRWLMGQMIIYSDNTATDMLIDLV-GL +QAVNGVAQTLAPRGIARITPLAEVRRAYYAEGLNSGRLDAYAQILVALAEGRALGAEATQ +TLLKLMEDVATGPQRLRAGLPPQARFAHKTGTQRR-RICDAGLVRMPARHPVVLVACVRD +AP-SLGRAEHLLAQTAAALC--- +>[subseq from] serine hydrolase n=1 Tax=unclassified Synechococcus TaxID=2626047 RepID=UPI00117DF0D8 +-----TTQAAIAADSTLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFFEAVD +SGKVNLDDSLTLTQEVIGGGSGGMQKTPGSTYTALYTATEMSVNSDNTATNMITELLGGN +AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARVNQGEILSVRSRD +RLFRIMGDTSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER +PYND-PKGKELLHKISRQFYDH- +>[subseq from] Serine hydrolase n=1 Tax=Spirosoma montaniterrae TaxID=1178516 RepID=A0A1P9X473_9BACT +---------------SARVSVAVESLMDSSVAfAYRADERVPSASVIKLSILLEAMERVK +AGTLDPDEIHILLDSEKTGGDGVLKTYSHRSIAYRDLLRLMLINSDNTATNIFINEL-GM +DAINARSQAVGLTQTRLNRLMMDTLA-VQQGRQNYVTAREMNVLLKKIYRHEVATPALCE +QMLDILKQTED-TATIPRLLPPGTVVAHKTGILNY-VRGDVGIVYAKN--PFLLSVFVEG +TT--TPEAEKIIGEVASTCYHFf +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora avicenniae TaxID=1198245 RepID=A0A1N7F0Z2_9ACTN +-----GQLQQVVDASTANAGVTVRDLSGDQQI-AVNGTFRPKAASVIKLWILVELLRRVD +CGQVSLDDGVLVTPAQVVDGTGELQHETFPQVTLHRLAEYMIKYSDNTAANVLIDYFGGF +APVNDLIDSMNQRETILARKMLDTEAA-MRGEENYTSPDDVVALLGAVWDAQILTPASRD +LMIAFMAEQTL-NTKIPAALPPGVPVAHKTGDLPD-TSHDVGYYLLPSSQ-VAVAFLTSG +PM---AGGDETVRRLARTVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium neonatale TaxID=137838 RepID=A0A2A7MDV8_9CLOT +---LTNRINHIIKNSSADIAVLVKDLKEDKVIfKYNEDKKYVSASIIKVPIMIEALSRVD +LGEINLDDKFNIGDDNKVDFSVITEQDLK-ECTFEELIEWMIISSDNTATNVLIDIL-GL +ENINDRIKKLNMKNTLLERKMMDFK-AIEYGRNNYTSLNDMLIAMEGLYRGVLISSEMSL +KAIDILKNQRD-NFMLKRYIRDNVTLANKTGELDK-LNNDVGIFYTKNHN-YFIGIFVHD +VKKN-KDAYEIIGKISKEVYDYy +>[subseq from] Uncharacterized protein n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=A0A147GQS8_9BURK +--RMATAMQQLEALQRTEVGVYVLDLASGQSF-GHRAEERWYLASMVKVPVAIAVLQAVE +RSDITLDTPLTLRAADKVDGAGATLRQPGSALTVRWLMGQMIIYSDNTATDMLMNLV-GL +QAVNGVVKALAPQGIGRITTLAEVRRAYYAEGLNSGRLDAYAGILTALVQGKALHPDSMQ +TLLKLMEDVATGPQRLRAGLPPQARFAHKTGTQRR-RICDAGLVRMPGTHPVVLVACVRD +AP-TLPRAEHLLQQTAAALC--- +>[subseq from] serine hydrolase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI0011DCFA0E +-qTIEHDILALIEAFNGKIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLKNTVLKRKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLMKESQE +RILRVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +IK-SEEESRQVISKIGKLIYD-- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Gammaproteobacteria (miscellaneous) TaxID=33811 RepID=A0A1Q6WM72_9GAMM +------------KKSGADVAVAFRTLDGRTQW-LRRPDEPFHAASTMKVAVLIELYRQAR +QGKLKLDDPLSVKNESLVDGSAFAYRAGG-GRTLRELSELMITVSSNLAANLLMDRL-GV +ENIRAGVRALGADGMNVLRDLEDAKA-FEQGLVNTTTAQALLTLLEAIARGQAVDRESSR +QMLETLERQTI-NDGIPAGLPAGTRVAHKTGDITR-IWHDAGIVLA--RRPFVLVVLTRG +LEN-PKESTALIAEITRELYR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Lysinibacillus chungkukjangi TaxID=1202712 RepID=A0A318TVJ5_9BACI +----EKNLQDLIEQVPYKVKLVVKDCAEPNQF-LFTKDDVFSSASLIKVPILVAVLEFLE +NKNESIHQIVKIAEENRVDFSVLSELEVS-EASLYELLVWMIITSDNTATNVLIDFW-GM +ENLNHYFKKIGLKNTTIQRKMMDFEQ-LEKGFDNLTTAREMAFLFEAIYRQDLLSKKSSE +LASDILSRQRI-QDSLKRYIADDVKVAHKTGSLET-VEHDIGIFFSKKR-PYIIGVFVTD +HTN-TEEAKSFIGKLSKIIYDHf +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F77AEA8 +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIYSDNTASDMLIRLV-GI +EQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus sp. SYP-B805 TaxID=1578199 RepID=UPI0013ECF7AF +--TLHDRIMALVEKAGGTWGIVLEDVHTNERW-TLNEDHRFFAASLIKVPIMTAVFAEAY +AGKFAFEDKLKLRQEDLVGGSGVLQHMTPGTLTILDLVTLMIIQSDNTATNLLIDLV-GK +ESIREIMRKTGMTNSQFYNKLMIIPAELEG--YNEVTAADMARHLKLLATGKAISYDSCL +RMIAILKKQQV-RDSLPYHLPDPWELANKTGSVST-NEHDCGILYVGQSA-VIIAALSHQ +VP--TKTARDTIGRIGELVYNLy +>[subseq from] serine hydrolase n=1 Tax=Romboutsia timonensis TaxID=1776391 RepID=UPI0008DA4E09 +----QEKIIKLLEGCSGKIGFYYKDLNTQNEI-KYNEDVKFMAASIVKLPILIEALRRLE +SKDISDLEKIAITKYMKVPCGALTYMHDGIEVTIRDLCNLMIILSDNTATNVLIDRL-GI +DEINKTIKNLGLKNTILSRKMYDMESK-KLGNENYFSLSDMAIILESIHNETLISQSVSK +EIKTIMKEQQI-NHKIPYYIPEDVTILHKTGEAD-GITHDIGIVYSKN--PFIIGFASNE +TN--IQEFEDIIRKISRFIYE-- +>[subseq from] Serine hydrolase n=1 Tax=Gottschalkiaceae bacterium TaxID=2527676 RepID=A0A521J512_9FIRM +----IENINRYIEGAKGEVSLVLKDLTNDKWIyTLNGNKPVQSASTIKVLIMVEALNQVL +QGKYSLNQIIDIREEYKVKYSMITDMTLK-SYPYLDLIILMNIVSDNTATNILIDLL-GY +ENINEMARKLGLKNTVLRRKMEEFK-AIKEGRDNYTSAMDMGVIMESLYRNLILTPEMCS +LALDILKRQKY-KDVLLRLISEDVKIAHKTGGLRN-LSHDIGIFYLDSVD-YLLGVFVTE +AES-DVEAKEIIGKISKVVYNYf +>[subseq from] Serine hydrolase n=2 Tax=Lysinibacillus TaxID=400634 RepID=A0A410ML84_LYSSH +----ENQIQNLIQKTPYKVHLFVKDPKTEQFLfSHQLEESFSSASIIKVPILLAVLAYTG +KHNISLHSALTITPTDWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM +DFLNDYFRQIGLQETLLQRKMMDVER-LAMGIDNFTSARDMAHLFTRIYQQDLLASPYNE +LVIDILSRQRV-YEGLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYGSSFD-YLIGIFITN +VT-DNDLARQLIGRLSKVVYDH- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SYJ5_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGNNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] CfxA6 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=C8C0D8_9ZZZZ +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGNNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A127SV59_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGNNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Latescibacteria bacterium TaxID=2053570 RepID=A0A3D2RNC0_9BACT +-----KDLTSFAKTFAGVLGVSAVHLETGKQV-AYNSDHPLLTASTFKSILLVSLLERVD +AQELSLDDRIAFTTTKRVAGSGVLKLMKSDTFSIGDLAVLMITISDNTASQMLFDVV-GH +SRIRHTIDRLGLTHTQIPLSPKEMILA-YSSEGNVSTPADMCRLFRRIHNNEVLSCKSTR +IFLDIHKGQQL-RSVIPHRLPAGTVCAHKTGQFEL-VSCDVGIVYSNHG-PYAIALMAND +TRGDRIEVDTSLAALSRTVFDQf +>[subseq from] Beta-lactamase class A n=1 Tax=Lysinibacillus sp. AC-3 TaxID=1680467 RepID=A0A1T5B7Z3_9BACI +----KQTITEILQNAPYNVHMFVKDCKTEQFFiSEKLEDTFSSASLIKVPILLAVLNYLE +SNNHSLEQEIEIAPEEWVDFSVISEQRLEQ-STIYELLVWMIITSDNTATNVLIDFL-GM +DALNHYFRQIGLKQTIIQRKMMDFEK-LAKGFDNTTSASDMALLFSRIYRKDLLSSAFNE +LTIDILSRQRI-HESLSRYLVDDVKLAHKTGGLET-VDHDAGIVYSRSGD-YLIGVFVTE +VTN-NDYARQLIGRIFKVVYEY- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium carnis TaxID=1530 RepID=A0A3P6JKA4_9CLOT +---LTNRINHIIKNSSADIAVLVKDLKEDKVIfKYNEDKKYVSASVIKVPIMIEALSRVD +LGEINLDDKFNIGDDNKVDFSVITEQDLK-ECTFEELIEWMIISSDNTATNVLIDIL-GL +ENINDRIKKLNMKNTLLERKMMDFK-AIEYGRNNYTSLNDMLIAMEGLYRGVLISSEMSL +KAIDILKNQRD-NFMLKRYIRDNVTLANKTGELDK-LNNDVGIFYTKNHN-YFIGIFVYD +VKKN-KDAYEIIGKISKEVYDYy +>[subseq from] Beta-lactamase n=2 Tax=Aquisphaera giovannonii TaxID=406548 RepID=A0A5B9VZB5_9BACT +--TLTSRLEPLIRAHKGKVAIAVKNLKTGEEF-HHRGAEVQPTASLIKFPVMVEAYRQAA +EGKVDLDARITLRAEDKVPGSGILTDHFSAGIALKDAIRLMIMSSDNTATNLVLDAI-GI +GATAATMESMGYPNTKIHSKVFRRDTRSKAYGLGSTTADEMVRLLEALHAHRLASPSACD +RMIEHLRTCDD-RDKFPKGLPYGTKVAFKTGSVDE-ARTAAGLIDCPDGT-VALCVLTCE +NQVPDNAGNVLCADVARAVFAHf +>[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A5P0WHB6_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGYNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNEPQASQFVAHISAVVYS-- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Parabacteroides goldsteinii TaxID=328812 RepID=UPI00101E0606 +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNVSYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium ragsdalei P11 TaxID=1353534 RepID=A0A1A6AKR7_9CLOT +-----EKILDVIDLKKLNCAFVIENLKTGEKI-AYNENVVVPSASLIKIPIMMEILNQVK +EGKLSLKQRITVNDNVKVPFSILNLLESGNSYTLKDIITLMIIQSDNTAANILMDLA-GM +DNVNNYVKNLEIKNTVLQRKMMDSQAR-KEGRENKTTAADMAKFFEIIYKGEKAKESHSV +IMKNILTAQLD-NSVMRLNIPDDTLIAHKTGDLD-GISHDAGIVYLPNVD-YIFCGLTWD +AV-TNNFARETIGKISKIAYDYf +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7A3836 +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIYSDNTASDMLIRLV-GI +EQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] class A beta-lactamase n=1 Tax=Muribaculum intestinale TaxID=1796646 RepID=UPI001093E7EF +--HIEDRLATYIAAQDARIGIAVI-IDGRDTV-SVNGNRDFPMLSVYKFPQALAVADYCM +KNGIGLSDTISIHGYEMKEWSPMRDRYGMGDLPLSELLEYSLRDSDNNACDILFRLIGGT +HVADSLMKAMDFDDIVIASTEDEMHRDIYLCYQNRSTPIAMAGLFDRFYRQEMRHSPLHE +AIGRIMMTCTTGNRRLPAPLPTNAVIGHKTGTGDVNGVNDAGYVFLPDGRGYAVAVFIAD +SACGMEETERMIADISDIIFQ-- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A521MSD1_9BACT +--ELLKKIQARLSAETGEFALAFRDLQTKEQI-LWNDRTSFHAASTMKTPVMVEVFKQVA +AGKLSLTDSLVVKNESIVDGSLYTYRLVGTKVTLYDLVYQMIILSSNLATNMVIELV-DG +KKVTQTMRELGAKDMQVLRGVEDGK-AFEKGLNNSVTAYDLMILYQALAAGTIVNSKACE +DMIRILLDQRY-NDIIPAYLPKELKVAHKTGSIT-GVHHDSGIIFLPDGRKYVLVILSRK +LA-DADKATEAMARVSEMIYRY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A212NCV2_KLEPN +------KLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELTAAALQYSDNVAMNKLIAHVGGP +ASVTAFTRQLGDETFRLHRTDPTFNTDIAGDPRKLPSSWAMA------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000311DCAE +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +EQVNAITRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STAQAERALRGTGEAVA--- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Parabacteroides sp. AM17-47 TaxID=2293118 RepID=UPI000E941E34 +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNMLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A2S6DA69_STAAU +------------------------------------------------------------ +-----------------------LEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus butanolivorans TaxID=421767 RepID=A0A2A7W7C9_9BACI +-qTIEHEILALVETFDGRIAYKIEN-ADGDTI-SYHDDEPFQSASLIKIPMIIEGYRQSE +EKKIYLNQPVTIPPIEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMTLL-GH +DEINQCIKELGLKNTILGRRMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE +KILRAFDNQQL-RDKLPSLMGKEVKVASKTGAIR-GVAHDCAIIRSEFQT--VYAVVLTE +DMKSEDESRQVISKIGKLIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Salegentibacter salarius TaxID=435906 RepID=A0A2N0U312_9FLAO +-qELQKKIASIFEENHGDFAIAFKNISEEKDSiLINAHKNFHAASTMKTPVMIEVFKQAS +EGKFSLQDSLVIKNESILDGSSYSYEQIGQKRSIEDLVTDMIIYSSNLATNIIIELV-DA +KNVNQTMREIGAMDINVLRGIEDMK-AYEAGLSNSTTAYDLMLIFEALAKGKAVNAEADK +QMLQILQQQKH-TDLIPALLPENLKIANKTGWIT-GVHHDSALIELPDGKKYVLVLLSKN +MK-DMEAGTKMLAEVSKLIYDH- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000C9B9EB1 +----LARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRIE +QDDLTLDSRVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +DQVNAVTRELVPEGFGPITTLADVRRRYYATLFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGARRIKAGLPSDTVLAHKTGTQR-ARICDAGLVDQPGTQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacF n=1 Tax=Planctomycetes bacterium Pla111 TaxID=2528000 RepID=A0A5C5WFD3_9BACT +---LQAALAPMIDAHRGTVAVRFEHLVTGDAY-AYQADQQMPSASLIKLPVMMAAYEAAA +RGALSLDERCVFEEADKTPGSGLLSTHLSPGLSLRDMIRLMIGWSDNAATNVVIERV-GI +KAVNDLMDRLGCPHTRLNSLVFKRETLSAKYGLGVMCPKETVLLLKRLAEDDAAVKEMSE +EMREHLRACQS-TSMAPRLLPDGVVIAHKTGSVAD-ARCDAGIIESPVG-PIAYCVMTAD +NVSDENEAAKLIAEVTKAAYDRf +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI0009B2D86D +------------------------------------------------------------ +-----------------------LEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] serine hydrolase n=1 Tax=Bacillus butanolivorans TaxID=421767 RepID=UPI000E29783D +-qTIEHEILALVETFDGRIAYKIEN-ADGDTI-SYHDDEPFQSASLIKIPMIIEGYRQSE +EKKIYLNQPVTIPPIEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMTLL-GH +DEINQCIKELGLKNTILGRRMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE +KILRAFDNQQL-RDKLPSLMGKEVKVASKTGAIR-GVAHDCAIIRSEFQT--VYAVVLTE +DMKSEDESRQVISKIGKLIYD-- +>[subseq from] Beta-lactamase n=1 Tax=Olsenella sp. DNF00959 TaxID=1476999 RepID=A0A134A1M2_9ACTN +---IQAAVEAALAGHSGSAYVAYESVDGSTTGfSLGGEERVPSASMIKTVVMATLLQEAQ +DGRISLADGTILRGQDRVAGSGVVQGMRAGTLSYGQLAAYMIGQSDNMATNLLIDAL-GM +DAVNEECQRLGLADTSLRRKMMDTVAA-ASGRENYTSASDQARLLLMVARGELVSPEASE +RALGWLEDQAD-TRGLAQGLPDGVAFAHKTGSLD-GVRHDGGIVLG--DHPYVLVVMTTG +MD--QGQADALMARVSTAVWE-- +>[subseq from] Serine hydrolase n=2 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6IC55_9BACT +-kKLEARVEEITSRLDGVMGVAILDLTDGRIL-LRNADHVFPAASSIKLAILLELYRQDQ +QGKAKLDDIYTFDSKDLVEDSQIMAGLSAGVLTNRDLAQFTVAVSDNTAANILYGRV-GR +ENVNAMLRGLGLSKVMLRRKMMDVAAA-RRGEENVATPQEMVRLLEAIHKEKVLNKKSTA +EFIKQLSTLKE--SYIPRCLPNGIQVANKPGNLE-GVRTDSGIVFVLNR-PFAISVMTAY +DR-DERAAERAISKVALEAYHYf +>[subseq from] Serine hydrolase n=1 Tax=Nocardia otitidiscaviarum TaxID=1823 RepID=A0A516NL39_9NOCA +---AETRIRAVFADAGCTGWLHARRCDSGTEI-SLGGDERVVVASVYKLPLFVAFCRQID +EGRIDPTARITVTPSDCTPPTGIAALRDPVTMSLRDLAASMMTVSDNAAADVLLGEI-GL +AAVEELLDDVGLTRTRIVGGTADLHRAYDPSYTSATTPEEMTRFLHALWRGDILSPERTD +YARAVMRAQVW-QHRIAAGFPRSVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLPAVDAAIAEVARIAVT-- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=UPI00118430A3 +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGVNEAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Leptolyngbya sp. DLM2.Bin27 TaxID=2480213 RepID=A0A5Q4EEY6_9CYAN +---LKGELEQLATLTPGTPVAFAIDLDSGQYV-DLGGAEPVAAASTIKVPILMAFLQQVD +AGNMALNQSLALREEHLAGGSGTMREAVGTEYTALEVATQMIVISDNTATNMMIAALGGI +EALNQTFVAWGLEHTLLRNPLPDLEGT------NITSAKDLALIMALIDQGGLLSTRSRD +RLFSIMQRTQN-DSLIPSGIRDRSLTANKTGDIG-GMLGDVALVDVPNGKRYSLAVLVQR +PNND-GRASELIRRMTETVH--- +>[subseq from] serine hydrolase n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=UPI0009EA9922 +--RMATAMQQLEALQRTEVGVYVLDLASGQSF-GHRAEERWYLASMVKVPVAIAVLQAVE +RSDITLDTPLTLRAADKVDGAGATLRQPGSALTVRWLMGQMIIYSDNTATDMLMNLV-GL +QAVNGVVKALAPQGIGRITTLAEVRRAYYAEGLNSGRLDAYAGILTALVQGKALHPDSMQ +TLLKLMEDVATGPQRLRAGLPPQARFAHKTGTQRR-RICDAGLVRMPGTHPVVLVACVRD +AP-TLPRAEHLLQQTAAALC--- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0013E408B9 +------------------------------------------------------------ +------------------------KRQVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A5P0WVM9_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPHSSFQIAYTEEEMSADPDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGNNGAHNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Synechococcus TaxID=2626047 RepID=A0A4P8X313_9SYNE +-----TTQAAIAADSTLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFFEAVD +SGKVNLDDSLTLTQEVIGGGSGGMQKTPGSTYTALYTATEMSVNSDNTATNMITELLGGN +AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARVNQGEILSVRSRD +RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER +PYND-PKGKELLHKISRQFYDH- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. PCC 8807 TaxID=195248 RepID=UPI0008103457 +-----TTQAAIAADSTLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFFEAVD +SGKVNLDDSLTLTQEVIGGGSGGMQKTPGSTYTALYTATEMSVNSDNTATNMITELLGGN +AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARVNQGEILSVRSRD +RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER +PYND-PKGKELLHKISRQFYDH- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. NKBG042902 TaxID=490193 RepID=UPI000694509C +-----TTQAAIAADSTLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFFEAVD +SGKVNLDDSLTLTQEVIGGGSGGMQKTPGSTYTALYTATEMSVNSDNTATNMITELLGGN +AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARVNQGEILSVRSRD +RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER +PYND-PKGKELLHKISRQFYDH- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. PCC 73109 TaxID=374982 RepID=UPI0007458EB7 +-----TTQAAIAADSTLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFFEAVD +SGKVNLDDSLTLTQEVIGGGSGGMQKTPGSTYTALYTATEMSVNSDNTATNMITELLGGN +AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARVNQGEILSVRSRD +RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER +PYND-PKGKELLHKISRQFYDH- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI0009BAE9E1 +------------------------------------------------------------ +-----------------------LEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A0H3YWR8_PSEST +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +EQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STAQAERALRGTGEAVA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Cyclobacterium lianum TaxID=388280 RepID=A0A1M7Q6N9_9BACT +------------------VSLLIQD-EEGQTLfSQSADKRIPSASIIKIPILIALMEKVE +NREITLDARYSLQATDKVGGAGELQHLPDGSITFRYLAEEMIRISDNTATNILIRAI-EM +GYIQDWLKKNGYRDTQLNRLMMDFK-AIEEGRQNYTSPREINDILLNLWEGKWLKEDSRA +EIMHCLKGCAD-NSTIPSLLPAGTVVAHKTGTLDY-VRGDAGIILG--DKPLILSVFVEN +FE-SMEEAESAIGKIALKAFRDf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F1DI15_KLEPN +------------------------------------------------------------ +TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAVLSAPALQYSDNTAMNKLIAQLGGP +GGLTAFARAIGDETFLLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLLTWLKGNTTGAASIRAGLPTSWT----------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora costi TaxID=1530042 RepID=A0A3B0AEL5_9ACTN +------QLRQVVDASTANAGVTVRDLSGDQQI-AVNGTFRPKAASVIKLWILVELLRRVD +CGQVSLDDEVLVTPAQVVDGTGELQHEEFPRVTLYRLAEYMIKYSDNTAANVLIDYFGGF +APVNDLIDSMNQRETILARKMLDTEAA-MRGEENYTSPDDVVALLGAVWDAQILTPASRD +LMIGFMAEQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSE-TVVAFLTSG +PM---ASGDETVRQLARTVYDH- +>[subseq from] Beta-lactamase, putative n=1 Tax=Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) TaxID=32049 RepID=B1XL05_SYNP2 +-----TTQAAIAADSTLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFFEAVD +SGKVNLDDSLTLTQEVIGGGSGGMQKTPGSTYTALYTATEMSVNSDNTATNMITELLGGN +AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARVNQGEILSVRSRD +RLFRIMGDTSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER +PYND-PKGKELLHKISRQFYDH- +>[subseq from] Peptidase S12 family protein n=1 Tax=Flavihumibacter petaseus NBRC 106054 TaxID=1220578 RepID=A0A0E9N4Z5_9BACT +-----KSINAVLATHEATYGIAFKDIGSGQTF-YHNEKSSFHAASTMKTPVLIETYRQAK +AGKFSLTDSILVKNTSIVDGSPYSYQAIGKRLPINDILYRMITRSSNLATNMMIELV-GA +ENVMATMRSIGANDIRVLRGVEDDK-AFEKGLNNTTTAYDLMLIMEHIARGTAIDRQASQ +AMISILTDQYF-RDIIPARLPKEVKVASKTGSIN-GICHDSGIVFLPDGRRYVLILLSKG +IA-DLNTAKSVLAQVSEIIYKHy +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T0B4_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGHNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A3B8TFF2_PSESP +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +EQVNAVTRELVPEDFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus parabrevis TaxID=54914 RepID=A0A656ZL01_BREPA +-------VSELLEAAGGEWGVYLEDLQTNEKL-AINENERFYAASIIKVPIMTAVFAEAY +AGKLALEDKIKLRHEDLVGGAGVLQHMTPGTFTVYDLVTLMIIQSDNTATNMMIDLV-GT +ESIRSAMRKTGMENSSFYNKLMVVPAELEG--YNEITAADIGSHLRYLATGKVISYDSCL +KMIAILKQQQH-RDRFPFLLPPKWEFANKTGSVTK-ITHDVGIFYTGPH---AISVSLLN +KGLAQKDAAAVMARIGSLLYDAy +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A6A7UHM5_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGYNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNEPQASQFVAHISAVVYS-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus muralis TaxID=264697 RepID=UPI00070F07FD +-qTIEHDILALVEGFNGKIAYKIEN-GSGDTI-GLHKEESFQSASLIKIPMIIEGYRQSE +RKKINLKQSVTIPPSVVAGGSGVLHTLSNKVLTVEDLLTLMITVSDNTATNMMMSLL-GI +DEVNQCIKELGLKNTKLERRMQDFKA-LKEGRDNTISAEDTIICLKAIHTGDFLAKESQE +RIMRVFDNQQL-KDKLPSLMGGGVKIASKTGGIR-GVSHDCAIIRSEYQT-VYAAVLTEN +TR-SEEDSRQVISKIGKLIYD-- +>[subseq from] serine hydrolase n=1 Tax=Cyclobacterium lianum TaxID=388280 RepID=UPI0009FF0972 +------------------VSLLIQD-EEGQTLfSQSADKRIPSASIIKIPILIALMEKVE +NREITLDARYSLQATDKVGGAGELQHLPDGSITFRYLAEEMIRISDNTATNILIRAI-EM +GYIQDWLKKNGYRDTQLNRLMMDFK-AIEEGRQNYTSPREINDILLNLWEGKWLKEDSRA +EIMHCLKGCAD-NSTIPSLLPAGTVVAHKTGTLDY-VRGDAGIILG--DKPLILSVFVEN +FE-SMEEAESAIGKIALKAFRDf +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI0002D7A7D0 +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +EQVNAITRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STAQAERALRGTGEAVA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ295 TaxID=2512146 RepID=A0A4Q7ZZC2_9ACTN +------------------AGVAVRDLSGDQQI-AVNGEFRPKAASVIKLWILVELLRRVD +CGQVSLDDGVLVTPADVVGGTGQLQYTFPQVVTLYRLAEYMIIYSDNTAANVLIDYLGGF +APVNALIDAMNQRETILARKMLDTEAA-RRGEENYTSPDDVISLLGAVWDADILAPPSRD +LMIGFMRRQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-VAVAFLTGG +PI---ATGDEVVRRLARTVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=uncultured Candidatus Melainabacteria bacterium TaxID=2682970 RepID=A0A650EKP0_9BACT +---LQRELMNLMEEYTVKPAVYVWDYETGNYI-DINASKSYATASIIKIPVLIDVFKSIE +AGQFSLNDTMPLTEYYRTEGSGSMQFKARNSYTIDKLAELMITESDNSATNMLMAKVGSM +TDVNQAIRSWGLKNTSVQTWLPDLTGT------NRTTARDMAQMLYNIDEDKFLTEESRA +RIFNYMGHVHN-NRLIQAGLGVGSVFLHKTGDIGT-MLGDAGIVIAPNGRKYIVVILANR +PHNS-VAGKDFIVHASEIIYNY- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A3R5XPW7_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGYNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Paramuribaculum intestinale TaxID=2094151 RepID=A0A2V1IUI6_9BACT +--AMTSRLKEFTTGKDARIGIAVI-INGRDTV-SVNGHRDFPMLSVYKFPQAIAVADYCV +RHGISSADTVAVGHEEILAWSPMRDRYGIRDLPLSELLAYSLQQSDNNACDILFRLIGGP +QAADSLMNTLGFDDIVMASTEEEMHGDTYLCYQNRSTPLAMARLFDRLYRQGMRSESAHE +TIATMMIQCATGLNRLPAPMATNAMIGHKTGTGARNGINDAGYVFLPDGNGYSIAVFIAD +SAYDMAATEQLIAEISTIVFN-- +>[subseq from] Serine hydrolase n=1 Tax=Muribaculaceae bacterium Isolate-043 (Harlan) TaxID=2486463 RepID=A0A3N2L584_9BACT +--AMTSRLKEFTTGKDARIGIAVI-INGRDTV-SVNGHRDFPMLSVYKFPQAIAVADYCV +RHGISSADTVAVGHEEILAWSPMRDRYGIRDLPLSELLAYSLQQSDNNACDILFRLIGGP +QAADSLMNTLGFDDIVMASTEEEMHGDTYLCYQNRSTPLAMARLFDRLYRQGMRSESAHE +TIATMMIQCATGLNRLPAPMATNAMIGHKTGTGARNGINDAGYVFLPDGNGYSIAVFIAD +SAYDMAATEQLIAEISTIVFN-- +>[subseq from] serine hydrolase n=1 Tax=Gracilimonas tropica TaxID=454600 RepID=UPI00035CBEE7 +--ELEQAIESRLSGLEGTFGIAFKNLNNPDEYvFINEDERFHAASTMKTPVIVELYKRAE +SGEFDVQDSIVVKNTSIVDGSEFTYEKLNAKTSLYDLAYQMITRSSNLATNILIDFL-GA +ESVTQTMRSIGADSIEVLRGVEDIK-AYEAGLSNTTTPRDLLVLFEEIEQGALLNDRSKE +AIISILKDQKY-NEMIPAKLPAEASVAHKTGWITN-VHHDSGIVYMPDGRAFVLIFLSKE +AP-NREAVLDAAADIASYCY--- +>[subseq from] Serine hydrolase n=1 Tax=Cytophagales bacterium TaxID=2053541 RepID=A0A3D3IAB8_9BACT +--QLKEDINNELSKVEGEFGIAFKDLTTGETL-FINEKEVFHAASTMKTPVMIEVFKQAQ +AGHLSLADSILIKNDSIVDYSLNAYHQVGTMKPLSAIVYDMINMSSNLATNIVIELV-DA +KNVTLTMHDLGANDLLVLRGVEDSKA-FTAGLNNTTTAYDLMMIFEKLAKGKAVSPEADQ +QMIDILLDQKF-NEIIPAQLPANVKVAHKTGTIT-GVQHDSGIVMLPDGKEYVLVTLSKN +LT-DSEKGVAAMANVSELIYKH- +>[subseq from] Serine hydrolase n=2 Tax=filamentous cyanobacterium CCP3 TaxID=2107704 RepID=A0A2T2VXW7_9CYAN +---LKGELENLATLTPGTPVAFAVDLDSGQYV-DLGGAEPVAAASTIKVPILIAFLQQVD +AGTVALNQSLMLQEEHMAGGSGTLREAVGTEYTALEVATRMIVASDNTATNMMIAALGGI +EALNQTFAGWGLEHTVLRNPLPDLDGT------NTTSAKDMALIMALVDQGGLLTPRSRD +RLFSIMQRTEN-ISLIPSGISDTSLTAHKTGDIG-GLLGDVALVDVPNGKRYTLALLVQR +PTND-GRASELIRRMTETV---- +>[subseq from] serine hydrolase n=1 Tax=Xylophilus ampelinus TaxID=54067 RepID=UPI000825E24D +--ALGAQIDRIDRDTPGELGVYVKRLNGGETY-SHGAERFWYLGSMTKVPIAVAVLQQVD +AGKLKLSDTVELQDADRIDVSRVVRERTGRRYTVDALLDRMLKDSDNTAANMLIRTV-GE +DTVQRAAQALGTQGFK-------------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Xylophilus ampelinus TaxID=54067 RepID=UPI000825E24D +------------------------------------------------------------ +----------------------------------------------NTALVQVANAPLGP +GRVQAVQRALKLKNGDLQRTIDDAYDRYYRHDINAATLDAYGAMLEKLARGELLKPASLQ +RLYAAMKLGTFTNHRLQAGLPRSEPFIHKTGTQYK-RACHAGVLRPQDRADAVVVAVCAA +GMDEHKDVDAVFQQVGRAIAQ-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=A0A415FEF9_9BACE +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A210Y0E9_PSEST +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +DQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STAQAERALRGTGEAVA--- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus capsici TaxID=2115968 RepID=UPI000E202E16 +----EQRITTLIQESPYNVHLFIKNLTTNQLLiSHQLETSFSSASLIKVPILLALLSYIE +KNKLSLNSTLTISPTNWVDFSVISEQRLTQ-STFYDLLLWMIITSDNTATNVLIDVV-GM +EYLNDYFQHIGLQDTLLQRKMMDVER-LAKGIDNRTSARDMAHLYTRVYQQELLAPTYNK +LVINILSRQRI-HDSLKRYLVEDVRLAHKTGGLDT-VDHDVGIFYTNAV-DYSMGVFITN +VT-DNDQARQLIGRLSKVVYDQ- +>[subseq from] Beta-lactamase n=1 Tax=Fusobacterium nucleatum subsp. polymorphum ATCC 10953 TaxID=393480 RepID=A5TRP4_FUSNP +-tEWKKEIEKIISQVEGKVCVNFYDLNKNNGF-SINGDKKVLSASMIKLLILTELMKKIS +EDKFSLSDTIMMANFMKTGGDGVLKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] serine hydrolase n=1 Tax=Proteiniborus ethanoligenes TaxID=415015 RepID=UPI000B82F269 +----IENINRYIEGAKGEVSLVLKDLTNDKWIyTLNGNKPVQSASTIKVLIMVEALNQVL +QGKYSLNQIIDIREEYKVKYSIITDMTLK-SYPYLDLIILMNIVSDNTATNILIDLL-GY +ENINEMARKLGLKNTVLRRKMEEFK-AIKEGRDNYTSAMDMGVIMESLYRNLILTPEMCS +LALDILKRQKY-KDVLLRLISEDVKIAHKTGGLRN-LSHDIGIFYLDSVD-YLLGVFVTE +AES-DVEAKEIIGKISKVVYNYf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides fluxus YIT 12057 TaxID=763034 RepID=F3PNS1_9BACE +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGNNGAHNDVAYICLPNNVSYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase 1 n=2 Tax=Planctomycetes bacterium Poly30 TaxID=2528018 RepID=A0A518EQL6_9BACT +-----EAIAAATTRSDGEVFVAYRDLGDGASW-DVRGDTVVHAASTMKVPVMVALHRRAF +EGRFDLEAPMNVHNSSIVDGSPYTYDRVGESLPASELCRRMIVRSSNLATNLLVDEL-GA +DQIQRTIEGLGVRHMRVLRGVEDGK-AYRAGLSNTATASDLRELLTAIAEGVAVSPEHSD +AMLETLAAQEF-SELIPAGLPEGIRVAHKTGSIT-GILHDAAIVMPEGVPPYVLVILTRD +FA-DSKDAADAIREVTRRV---- +>[subseq from] serine hydrolase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI0012963AE1 +-hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVE +----KLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP +PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGA-------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus simplex NBRC 15720 = DSM 1321 TaxID=1349754 RepID=A0A223EE15_9BACI +-qTIEHDILALIEAFNGKIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE +QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF +EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLMKESQE +RILRVFDNQQL-RDKLPSLMGRGVKIASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED +IK-SEEESRQVISKIGKLIYD-- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. CAG:1320 TaxID=1262922 RepID=R6ETJ0_9BACT +---LTDSLSRIASACPGEMGVAVI-VNDTETI-TVNNQSVYPMMSVFKVHQALALCDDFD +KRGLSLDTLIRINRSELDPWSPMMKDHPERILTIRDLLRYTLTQSDNNASNLLFKRLVDV +AKTDSFVATIPRPSFRIVYTEEEMAVDHDRAYSNYTSPLGAAMLMNRLFTDKLVSDGKQD +FIKNTLKECETGTDRIVAPLEPDAVIAHKTGSGYNGAHNDVAYICLPNNISYALAVFVKD +FKGNEAQASRYIARASAVVYS-- +>[subseq from] serine hydrolase n=1 Tax=Ureibacillus thermosphaericus TaxID=51173 RepID=UPI000BBC6272 +-----EQIRTLLDEADCKVHLVVKDLKTDQYLiAEKMDEVFPSASIIKVPILLAVLHYVQ +ENQFSLTDVVEISPENKVDFSVITEQDLT-SCTIYELLLWMIITSDNSATNELIDLL-GF +EKLNHYFKKIGLAHTNLERKMMDFEK-INLGYDNVTTARDMAHLFSLIYQQQLLIDEFNK +IAIDILCKQRD-YERLKRYIA-DVRIAHKTGSLDT-VCHDAGIVYHPTMD-YLIGVFLTE +LN-DFEFGKRFIGRISKIVYDYf +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=UPI001290E54C +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPHSSFQIAYTEEEMSADPDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGYNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNEPQASQFVAHISAVVYS-- +>[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus locisalis TaxID=305507 RepID=A0A1I7DBX9_9BACT +--TLQEQLQSKLDSIQGDVAVAFFNLSDPSDSlLINADEEFHAASTMKVPVMIELYKQQE +AGNLDLNDSILLKNESIVDGSPYSYSKIGTTVALKDLMFPMITVSSNLATNVLIELV-GA +KNVTATMRDLGASKIEVLRGVEDQK-AYDLGLSNSTTAKDLMIIMAAIAQNKAGTKKDCD +EMIQIMKDQQF-NEIIPFYLPEDVAVAHKTGSIT-GVHHDAGIVYLPDGRSYVLVLLSKN +LE-DFDKGTEQLAGISKTVYEY- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A2U8SQD7_PSEST +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +DQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STAQAERALRGTGEAVA--- +>[subseq from] serine hydrolase n=1 Tax=Spirosoma spitsbergense TaxID=431554 RepID=UPI0012F8599E +-----------------RVSLSTRSLVDATLSfAYRADVRVPSASVIKLPIMLELMERVK +AGMFNLDAMHTLTEAEKVGGDGVLQTYADQSVSYRELLRLMLIKSDNTATNIIIHLL-GR +DAINQRLRKSGLERSQLNRVMMDTLAA-KQGRENYVTAQEMNALLEKVYRHQVATPEGCE +AMLTILKQNED-VLTIPRLLPKSVVIAHKTGTLAY-VRGDAGIVYAE--KPFLLAVFVEG +VP--TPEAERIIGEVVLICYTYf +>[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T028_9BACT +-tALQNELTDFVKDKDARIGMAVI-IDGKDTV-AVNGKEDFPMLSVYKLPIALALADNYR +VKGLDFSEPIAIAKEDLHLYSPMTGRLLASSMPTREILNYMLHQSDNNASDLAVKKLGGT +ENVMKWLSKSGLSGVKVVSTENEMHINPELSYKNSSTPIAMARLLDKLDTE--WNDSLSK +EIKQMMETCKTGENRLAKLLPTNAVTGHKTGTGFIMAVNDVGYVHLSNGHRYSIAVFIAD +AHYDMAESENIIAQISEMVWR-- +>[subseq from] Serine hydrolase (Fragment) n=2 Tax=Clostridiaceae bacterium TaxID=1898204 RepID=A0A353JXU4_9CLOT +---LKKEIKAFIKTQSGNIAVSFYDLNEKSGF-SIDGEKRMLSASTIKLVIMAELMRRVH +IGEISLENKITVTVQMKTGGDGILKELEPGHFTIKELLTLMIIISDNEATNILIDFL-GM +ESINQMAQAMRLKQAHLGRKMMDSEA-KKAGHDNYICAEDIRDILKSIYEGTCIDGKSSK +MMLNILKHQQQ-SGRLQLYLPEEVEVAHKCGDLDC-LENDGGIFFLPKH-PYILVVLTNE +MP-TNKDGREAIGKISWIVYQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Pseudohongiella sp. TaxID=1979412 RepID=A0A2D9DQ34_9GAMM +-------VAAASNNIRMSIGVAGLAGVNDDAMvLLGSSESYPPASTIKMLLIATLMHQVD +AGMLSLDDTTTVEQSDIVGYGEIQNELVPNEVTLRRLAQLTVTVSDNTATNVLVDVV-GY +DAMQALADTLELQDMQFGRKMFE--AATPPAKENYITAADSIKLLKAIYDGEFLSESSRQ +TVIDWMSAQTV-KTKIGAGIPADVPIAHKTGENAS-VTHDLGYILWPGN-EVALAIFAQS +EETDQATVNPVVAEVAGIIYEH- +>[subseq from] Serine hydrolase n=1 Tax=Verticiella sediminum TaxID=1247510 RepID=A0A556AE82_9BURK +------------------------------------------------------------ +--------------------------------------------------------I-GP +ARVRAVRDALDVGEDALAATMPEAYARYYATQRNMAPLDAYGAMLERLVAGDLLSDESRA +RLFAYMKLDEDGDYRLEGGLPQGIPFIHKTGTQFE-QACHVGVAYPESGKRAVVVAACAS +GLDEAKEAGAVLRRIGRAVAD-- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI0003C5E01E +------------------------------------------------------------ +-----------------------LEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5WYP9_9BACT +-kKLETRVEEIASSLDGVMGVAILDLTGGRIL-LRNADRVFPAASSIKIAILLELYRQDQ +KGKAKLDDIYTFDPKDLVEDSRIMAGLTAGVITNRDLAQFLVAVSDNAAANVLYDRV-GK +DNVNAMLHSLGLPKTLLRRKMMDIAA-VRRGHENIATPQEMVRLLEAIFKEKALDKQATA +EFIKQLSTLKQ--SYLPRYVPESVQVANKPGELE-GVRNDSGIVFAQNQ-PFAISVMTAY +DR-DEKAAERAIGEVALEAYRYf +>[subseq from] serine hydrolase n=1 Tax=Leptolyngbyaceae cyanobacterium CCMR0081 TaxID=2292702 RepID=UPI0013D14FE7 +---LKTKLEELQELIELTPTIYVFDLDTGNYV-EVAGNAETPAASTIKLPILIAFFKAVD +EGRITVDQALAMQSNQIAGGSGDMQGQPPGTYTALEVATQMIINSDNTATNMMIDLLGGP +QVLNQQFADWGLTMTILRNPLPDIEGT------NTTSAQDLVRMIAHLHKGDILSLRSRD +RVMNILQRTYN-KKLLPAGVSETTISYNKTGNIGE-VLGDVALMDLANGKRYAIAALVRR +PEND-GRAQELIRRISQAVYQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Proteiniborus ethanoligenes TaxID=415015 RepID=A0A1H3MQ78_9FIRM +-----ENINRYIEGAKGEVSLVLKDLTNDKWIyTLNGNKPVQSASTIKVLIMVEALNQVL +QGKYSLNQIIDIREEYKVKYSIITDMTLK-SYPYLDLIILMNIVSDNTATNILIDLL-GY +ENINEMARKLGLKNTVLRRKMEEFK-AIKEGRDNYTSAMDMGVIMESLYRNLILTPEMCS +LALDILKRQKY-KDVLLRLISEDVKIAHKTGGLRN-LSHDIGIFYLDSVD-YLLGVFVTE +AES-DVEAKEIIGKISKVVYNYf +>[subseq from] Serine hydrolase n=1 Tax=Muribaculaceae bacterium Isolate-110 (HZI) TaxID=2486473 RepID=A0A3N2NKN5_9BACT +-aDLQRELQEYVSDKEARIGIGVI-VDGRDTV-EVNGHQRFPMMSVYKFPISLALADVCR +ADGMTFDDSCTVVASELHRYSPMTDSYADIDISIRELLAYTLQMSDNNASDILLKRAGGA +GRVDSYVRSLGVGDIDIRWSEAEMHADTARCRDNSCTPLAMAALLSRFDAAD--DDALTA +EIKRLMETCATGTDRLLPPLEAGALLGHKTGTGDLQAINDVGYVHTPEGHVYSIAVFISD +SSLDMQSTSAMIAEISRMVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus composti TaxID=720633 RepID=A0A3N9UAK6_9BACI +----KQIIRQMIQDVPYNVHLFVKEAKENQFLiGEQLDAVFSSASLIKVPILLAVLDHLE +RTNQSLDHRLEITPENVVEFSVLTEQKVT-TCTIYELLVWMIITSDNSATNVLIDYI-GM +EGLNHYFSNFGLTQTKLQRKMMDFKR-LEQGFDNVTTARDMAHVFTSLYRQTLLSQHNNT +IAIDILSRQRI-YEGLKRYLVGDVKIAHKTGGLET-VDHDVGIIYTETVD-YIIGVFVTE +VSN-NDEARQLIGRISKVVYNEf +>[subseq from] Beta-lactamase class A n=1 Tax=Lysinibacillus sp. SG45 TaxID=1500271 RepID=A0A1H8BYX2_9BACI +----ENQIQDLIQKTPYKVHLFVKDPKTEQFLfSHQLEESFSSASIIKVPILLAVLAYTG +KHNISLHSALTITPTDWVDFSVISEQCLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM +DFLNDYFRQIGLQETLLQRKMMDVER-LAMGNDNFTSARDMAHLFTRIYQKDLLASPYNE +LVIDILSRQRV-YEGLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYGSSFD-YLIGIFITN +VT-DNDLARQLIGRLSKVVYDH- +>[subseq from] Serine hydrolase n=1 Tax=Psychrobacillus lasiicapitis TaxID=1636719 RepID=A0A544STV0_9BACI +---LVNKIRSLTEQSAGTWGIVLEDLDRGAKW-ISNGDELFYAASVIKVPIMVAVFSAVE +RGEISLTDELILKEDDFVGGSGVLQHLTPGTLSICDIVMLMIIQSDNTATNILIDLV-GV +EHIVQTMKEAGMEKSTFYNKLMMNNPR-PK-GYNQITANDIGKLLKLMATGKLASEEASK +QMIAIMKKQQI-KDCLPEKLPSPWELAHKTGWIP-GTRHDVGIFYVGQRK-LLATVLSKE +ED--DLLSKQILAEIGEEIYNY- +>[subseq from] Class A beta-lactamase n=1 Tax=Muribaculaceae bacterium Isolate-004 (NCI) TaxID=2489216 RepID=A0A4Q0IAF6_9BACT +---MTSLLKDFAAGKDARIGIAVI-INGRDTV-SVNGHRDFPMLSVYKFPQAIAVADYCV +RHGISSADTVAVGHEEILAWSPMRDRYGIRDLPLSELLAYSLQQSDNNACDILFRLIGGP +QAADSLMNTLGFDDIVMASTEEEMHGDTYLCYQNRSTPLAMARLFDRLYRQGMRSESAHE +TIATMMIQCATGLNRLPAPMATNAMIGHKTGTGDRNGINDAGYVFLPDGSGYSIAVFIAD +SAYDMAATEQLIAEISTIVFN-- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_60_11 TaxID=1797947 RepID=A0A1F9UFG0_9BACT +-qELEQSINYQIRHFPGQTAVYIRDLNTGWTI-EHNTDVLFPSASLVKLPIMAVLYQAQV +SGRLSLDESLPLLRKLKASGSGHLRFRRTGSIRVRELIYKMITESDNTATNMLTDRL-DL +DYINRHFLALGLNRTNFSRMIMDLRRR-DQGIENYTTAQDMGNLLEMIYFKNLT---GSE +EMLETLKNSKI-NDRLAMGIPSNWQIGHKTGLMNN-ACHDVGIVFSPTHD-YVICVLTTK +AR-RFRRAKGFISEVSHLAAMYy +>[subseq from] serine hydrolase n=1 Tax=Acidovorax wautersii TaxID=1177982 RepID=UPI000B89590C +------------------------------------------------------------ +----------------------------------------------------------GP +RRVQALARALGMPESQLQRTMDEAYARFYRRGDNTAPLVDYGAMLERLVRGQLVNAQHQQ +QLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQFQ-RACHMGVIDPQDGRRAIIVATCAE +GLDEQKQAGRAFEALGRAITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium sp. CAG:967 TaxID=1262849 RepID=R5KEM9_9CLOT +---LENQLKNLSAMYSIHPSIYVWDYDTGNYA-DVNADEVFPTASIIKLPVLVQLFRSIE +KNQLTIYDEMPLTEYYRTEGSGSLQFKAANSYTIDTLARMMITESDNSATNMIMARLGSM +TDINQGLREWGLKHTYVQTWLPDLGGT------NHSTARDMATILYNIDNPQFLSTSSRE +KIFDYMGHVHN-NRLIAAGLPAGAEFLHKTGDIGK-MLGDAGIVFAPNGKKYIVVIFANR +PHN-SPLGKEFIVKASETIYNY- +>[subseq from] Beta-lactamase n=48 Tax=Bacteroidetes TaxID=976 RepID=L1PB72_9FLAO +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. PCC 7117 TaxID=195498 RepID=A0A1B1U2B5_9SYNE +-----TTQAAIAADSTLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFFEAVD +SGKVNLDDSLTLTQEVIGGGSGGMQKTPGSTYTALYTATEMSVNSDNTATNMITELLGGD +AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARVNQGEILSVRSRD +RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER +PYND-PKGKELLHKISRQFYDH- +>[subseq from] Serine hydrolase n=1 Tax=Rufibacter sp. NBS58-1 TaxID=2595005 RepID=A0A5B6TW90_9BACT +-------VLAELGKQKGTFAVAFKDLKTGEEL-LINEHESFHAASTMKTPVLIEAYKQAA +EGRFSITDSILVKNESIVDGSPFSYTQLGQKRPLAELLYKMIIQSSNLATNIVIEQL-DA +KKVTQTMRELGARDLQVLRGVEDTK-AYRQGLNNTTTAYDLMVLFQLMAQGKTVSPAASK +EMIKVLLDQKF-KDVIPAKLPQEVKVAHKTGWIT-GVRHDSGIVFLPDGRQYVLVLLSKG +LV-DEKAGIQAMANVSEMIYRH- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A5Q5G016_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGCNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNEPQASQFVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A5N7TM30_PSESP +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +EQVNAITRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] serine hydrolase n=1 Tax=Peptoniphilus vaginalis TaxID=1756987 RepID=UPI000A26AF15 +---LQNKIENIVEESSANISVSFYDLDLEEGF-STDGDKQVPSASMIKLLILLKAFYECD +KGKLNLEDIISLDDYERVEGSGILKELYRNHFSIRELLTLMIIVSDNTATNILIDLL-GR +DEINKIGHELGLEKTILQRKMMDSLAK-EKGLDNFTSSNEILKILKMIYEKDFINEDYSQ +LALDILLRQQE-RDRLQRYLPEDLKIANKSGDLDN-LENDGGIFFTKNK-NYILVVLVNQ +AE-SNVLAKEIIGEISLKIYN-- +>[subseq from] Beta-lactamase n=1 Tax=Acidovorax citrulli (strain AAC00-1) TaxID=397945 RepID=A1TIK6_ACIAC +------------------------------------------------------------ +----------------------------------------------------------GS +QRVQALARTLQVQKDDLKKTMEEAYDRYYAWGTNTATLAGYGGMLEKLVRGQLLTPPHQQ +MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAQAIVVATCAE +DMDEMRQAGRLFEQLGRAITR-- +>[subseq from] Serine hydrolase n=1 Tax=Cystobacter fuscus TaxID=43 RepID=A0A250J7M9_9DELT +---LREALQERISQVGASVAVAYQRLGSPDSL-YLEADRSFHAASTMKVPVMLEVFRQVD +AGTLSLEEPVTLTRQSIVDGSPYEHERLGQPVPLRELVERMITRSSNLATNLVLSRV-DA +RRVTKTLRALGARRMTVLRGVEDGKA-HARGLNNTATARDLASLLSALEQGRAATPASTR +AMRSILLAQEL-NREIPAGLPPGTPVAHKTGQIS-GVLHDAAIVYPPGHPAYVLVVLTRG +IP-DEAVARSLIVELSRQVYAH- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella denticola TaxID=28129 RepID=Q8KT57_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRITAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase n=1 Tax=Cyclobacterium marinum (strain ATCC 25205 / DSM 745) TaxID=880070 RepID=G0IZA1_CYCMS +--QLEEEIRKLMNETEGDFALAFRSVDGEESElFFNEKETFHAASTMKTPVMVALFEQEA +AGKFSLQDSILIRNSSILDGSTYQYKRIGENATLYELMYEMIVRSSNLATNILIEKV-GA +KNVTQLMRELGAEDIQVLRGVEDLK-AYEAGLSNTTTALDMMLIMEAIAKHKV---AGSK +KMIDILSDQHF-NDLIPKYLPKEVKIAHKTGAIT-GVQHDAAIVELPDGNRYVLVILSKN +LT-DEKAGKECIAKISQMIYN-- +>[subseq from] Uncharacterized protein n=1 Tax=Anaerolineaceae bacterium TaxID=2024896 RepID=A0A2E0KYR2_9CHLR +--TLQSDIQTIIDESGIQAGVSVWHIERDEQT-DVNGDQPFPMASVFKIPILATAGKQLK +EGRISLDTRIELKDADKSAGSGILPYFEAGLPTVRDLLTLMIIISDNTATDMTVELLGGA +QVVESYMHEIGLGDIYFKMNCKDLLKFSTGPDNNVSTANAMTQLVHMIFQSEIVDGAIRD +ELLNILLKQQF-NVRLSRFLPPNVAFAHKTGTIG-GIRNDSGVIYINDDSHVIVTLFVWW +DDQRIFEVETAMGKIGKLVYDHy +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8R6C6_9BACT +--ALEGKVRGLIATSGATVAVAFQDLQTGREL-LINPGVSFHAASTMKVPVMLEIYRQAQ +FGKLSLDERLPVKNESIADGSTFSYKKIGGTETVRELLRLMITESSNLATDILIERV-TP +ARVMELMRRMGARDMRVLRGVEDGK-AFERGLNNTTTARDLLVLMRAIAEERAVSIIASR +EMARVLLDQKF-NEGIPAGLPPLIPVAHKTGSITK-IEHDAGIVFLSGRKPYVLVVLVRG +IAE-EARAHKLIADISRAIYE-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9IHN4_9BACT +haKLEAEINRVADQLNGVLGYAIKDLSTGESF-YRNADLVFPTASSIKLAVLLELMRQDQ +EGTLSLNEKHTVRHSELPPTDPILHMLGDGTMTLRDVATFMVVLSDNGATNILIDRA-GM +DNINAEIARLGLAQTHLRRRMIDIEAARRG-DENVSTPRELMVLLERVRGGGALDAAHTK +EYSDLLGLPK--DSLFNKALPSTVRIEDKPGALD-AVRSDAGIIEVPGH-PFAMSIMTTY +LG-SNDEGERAIKQIARLAYEHf +>[subseq from] serine hydrolase n=1 Tax=Olivibacter sp. XZL3 TaxID=1735116 RepID=UPI001066BF7D +---LTKKINEILQGAQGTFAIAFKDLSDNDTY-FYNEHEVFHAASTMKTPVLAEAFRQME +QGKFSLTDSVEVYNKSIYDGSPYSYALLGTKVTIADLLHRMITQSSNLATNIVIDLV-GA +KNVMKTMRQLGAKEMKILRGVEDSKA-FAHGMNNTVSAHDLLLLFEQLAKDSMVSKQASE +EMVAILMQQHF-RGTIPAKLPGTVKVANKTGSIDK-VFHDSGIVFLPDGRRYVLILLSKG +LEE--KRAQESLAEVSSVFYHY- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A3R5WK83_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGYNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Virgibacillus phasianinus TaxID=2017483 RepID=A0A220U3D5_9BACI +-kQLIDKIKTITKEAGGTWGISLEDLDTKETW-TSNGEQVFTAASVIKVPILIAAFAAFD +QKLLVPSDTVELKKEDLVAGSGVLQHMTPGTFTIYDLLTLMIIQSDNTATNMIIDLL-GA +EKINQTMEELGLKKSKFFNRLMIVPAN--REGVNQITALEMTAMLKQLVTGQVVSLYACE +QMIDIMKKQQL-QDCLPGRLPEAWQLAHKTGSVTR-VCHDVGIFYVGEK-TMIASVLSKG +ID--DIKAPGLFADIGFEIY--- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus gelatini TaxID=1655277 RepID=A0A3M8B2V4_9BACL +-------VSELLEAAGGEWGIYLEDLQTNEKL-AVNENQRFYAASVIKVPIMAAVFAEVF +SGKLALEDKIRLRREDLVGGAGVLQHMTPGTFTVYDLVTLMIIQSDNTATNMLIDLV-GT +DSIRSIMQKTGMENSSFYNKLMIVPAELEG--YNEITAADIGSHLRYLATGKIISYDSCL +KMIAILKQQQH-RDRFPFLLPPKWEYANKTGSVTK-ITHDVGIFYTGPH---AISISLLN +KGLEQKDAASVMARIGRLLYDLy +>[subseq from] Serine hydrolase n=2 Tax=Pseudomonadales TaxID=72274 RepID=A0A3R9BWX5_PSEST +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +EQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] Beta-lactamase n=2 Tax=Pseudomonas TaxID=286 RepID=A0A3S4PGW0_PSEST +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +EQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=UPI00048C361B +------ELQNLIQTLPGRYAVFAKNLETQKTF-AYHEHDIFPSASVIKVPILIELYRRVE +EDHLSLDHLLLMRKEDQVGGSGVLKDLTPGTYSLRDLATLMITVSDNTATNLLIDYL-GV +DWVNSTIRRLGTQNTELIRKLQRVPAE--YDQINHTCAYDMALLMEKLARGTAISLAVSE +QMVNLLTRCQ-GPVSIAKNLTKEVIVAHKTGSLSE-ASHDVGIVYSPHMN-YVAAILSEG +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Burkholderiales bacterium TaxID=1891238 RepID=A0A4Q3UQC8_9BURK +-----NAVQRLGTTFQGRIGISIREIDAGWTV-AFGGDASLPQQSVSKLWVGIATMQQIE +RGRLSLSDPILVHRSDLTVHQPLRPLVTANGTTVGSLLELAMTRSDNSANDILLWKIGGP +PIVRDMLSRDGVLGVGFGPGERDLQARYLAAPYDGASANGVTLGLALLAQGKLLKPSSST +HLLALMRASKTGPLRLRSGLRPGWTLAHKTGTGQATGYNDVGILVSPAGHRYAVAVMIAS +THQPIPARMRLMGDVTRAIIR-- +>[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3R472_9BURK +--RLRTQIERLDADTPGDLGVYVKRLDNGEAY-GHGADRRWYLASTVKVLIAIAVLQQVD +AGRLKLDAQVALQDSDRIDVGKLVWEKTGTRHRVDALVQRMLRDSDNTAANMLIRTLGGE +VPLNDSAAAAIDAELHPDARKLSNAQRYYRHQNNSATLEGYGAMLEKLVRGELLKPASLQ +RLNDGMKLGIYTNYRLQAGLPRGVDFIHKTGTQHQ-RACHAGVIRPQNQAQGVVVVACTA +ELDEQKAAGPVLQRVGQAVTQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus acidophilus TaxID=53633 RepID=A0A2T2WFD7_9FIRM +---LRMTLESLVAQLPGQYGIFARNLNTGQTI-AMGEHQVFPSASLIKVPILAEVLRRVE +EEGLSLDETLVMRAEDQVPGSGVLKDLTPGTYTLRDLSMLMITVSDNTATNLLIDYL-TV +DSVNALLRRLGLPQTSLERRLERVPAQ--VTRVNRTTAHEMARLMELVATGQLISQDVSR +RMIDRLQRCQAEDPRYIGQLP-AIQVAHKTGSLAQ-ARHDCGIVFHAKG-VFVASILSQG +APA--SQLQDRIHRIGQFIF--- +>[subseq from] Serine hydrolase n=1 Tax=Acidovorax avenae subsp. avenae TaxID=80870 RepID=A0A2R4EBK0_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +QRVQVLARSLHVRKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ +MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAHAIVVATCAE +GMDEMRQAGRLFEQIGRAITR-- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. PCC 7117 TaxID=195498 RepID=UPI0009FEA9ED +-----TTQAAIAADSTLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFFEAVD +SGKVNLDDSLTLTQEVIGGGSGGMQKTPGSTYTALYTATEMSVNSDNTATNMITELLGGD +AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARVNQGEILSVRSRD +RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER +PYND-PKGKELLHKISRQFYDH- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7R7T1_9BACT +--SLRSQVEARIARAPARVGVYYRDLATGDSL-TVGSGVRFHAASTMKIPVMIQLYRDRD +AGVLSLDDSITITNTSIADSSPYLYKRLGQRASIRELIELMETVSSNLATNLLIAKV-NA +TRANATAHALGADSILVLRGVEDGK-AYRAGLNNTTTARDLGMLLAAIANGTAASAASCR +EMLAILGRQQF-NEGIPAGLPPGTQVYHKTGWIGQVVYHDAALVEPAGRGRYVLVVLTGG +IQKD-ADSHALVRDISRLVFD-- +>[subseq from] serine hydrolase n=1 Tax=Ureibacillus thermosphaericus TaxID=51173 RepID=UPI00030D8C5C +-----EQIRTLLDEADCKVHLVVKDLKTDQYLiAEKMDEVFPSASIIKVPILLAVLHYVQ +ENQFSLTDVVEISPENKVDFSVITEQDLT-SCTIYELLLWMIITSDNSATNELIDLL-GF +EKLNHYFKKIGLAHTNLERKMMDFEK-INLGYDNVTTARDMAHLFSLIYQQQLLIDEFNK +IAIDILCKQRD-YERLKRYIA-DVRIAHKTGSLDT-VCHDAGIVYHPTMD-YFIGVFLTE +LN-DFEFGKRFIGRISKIVYDYf +>[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A3R6GVA8_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPHSSFQIAYTEEEMSADQDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGYNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Cyclobacteriaceae bacterium TaxID=2099675 RepID=A0A5C7Z8I3_9BACT +-eETSRQIETILSKPKGSFAVAYKDLLTGEEI-LINEHALFHAASTMKTPVMAEVYRQVA +EGKFSLKDSVLIKNDSILDGSSFSYDHIGEKRTVYSLMYDMIIISSNLATNLIVELV-DA +KNVTQTMRSIGANDIQVLRGVEDTK-AYEAGMNNQVTAYDLMLLFEKIDKEEIVNAEASM +AMMDILLDQKF-NDIIPAKLPAEVKVAHKTGSIT-GVRHDSGIVFLPDGKKYVLVLLSKD +LE-DEDAGVQAMAEVSEVLYQY- +>[subseq from] Beta-lactamase n=2 Tax=Prevotella TaxID=838 RepID=A0A096CAA3_9BACT +----TDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=SAR202 cluster bacterium TaxID=2030829 RepID=A0A5N9DS78_9CHLR +-----SEIKSLVSEINGEVGVAALNLKNDKNI-YINENESFFMASVFKIPLLITLYKQVD +LGNIDMDQRITLAQDLKTGGSGVLRELTPGIPTLFDLAMLMIIISDNTATDILFNML-GK +DKINSLMRQNNLSKTFTPMSCQDLLSALNEDKSNVSTAYEMVTLMKLLTTGKILSESSTN +SVLSILKSQKL-KTIIPHYIPKNIKIANKTGGVYS-VRSDVGTVWSPKG-PYTIALMAKN +VT-NEPDIDTKLAKISLSIYEY- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. B14905 TaxID=388400 RepID=UPI0000F3867E +----ENQIQDLIQKTPYKVHLFVKDPKTDQFLfSHQLEESFSSASIIKVPILLAVLAYTG +KHNISLHSALTITPTDWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM +GFLNDYFRQIGLQETSLQRKMMDVER-LAMGIDNFTSAQDMAHLFTRIYQKDLLASPYNE +LVIDILSRQRV-YEGLKRYLVDDVKLAHKTGGFDT-VDHDVGIVYGSSFD-YLIGIFITN +VT-DNDLARQLIGRLSKVVYDH- +>[subseq from] serine hydrolase n=1 Tax=Salinimicrobium terrae TaxID=470866 RepID=UPI000409E3B5 +-qKTEKKLQEIFQSSPAITGLVAVDLTSGEKI-SWNPDVQFPQASSIKIPILIEVFKQAS +EGKYSLSDRLPVNSTNLVGGTGILKNLDDPALSIKNLGILMIALSDNSATNSLIDLV-GI +PKVNKTLQSLGMKQTLLQREMMNSTA-SARGEENLATPAEAAKILQLLYKGEFINPNVSK +EIVDILKMTDREDSRLAAGIAENVDIAFKPGFIN-GVSVEWAIVNLQQR-PYAVAIMESH +KV--SGEAEEVMEDVSKILYNYf +>[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534B4Z7_9GAMM +------AIESTIKKSGADVAVAFRTLDGRTQW-LRRPDEPFHAASTMKVAVLIELYRQAR +QGKLKLDDPLSVKNESLVDGSAFAYRAGG-GRTLRELSELMITVSSNLAANLLMDRL-GV +ENIRAGVHALGADGMNVLRDLEDAKA-FEQGLVNTTTAQALLTLLEAIARGQAVDRESSR +QMLETLERQTI-NDGIPAGLPAGTRVAHKTGDIAR-IWHDAGIVLAS--QPFVLVVLTRG +LEN-PKESTALIAGITRELYR-- +>[subseq from] Beta-lactamase n=3 Tax=Bacteroidales TaxID=171549 RepID=G5SM21_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGSNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteroidales TaxID=171549 RepID=A0A4P8LYC8_BACFG +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGSNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase class A n=2 Tax=Pseudoxanthomonas wuyuanensis TaxID=1073196 RepID=A0A286CYM8_9GAMM +--ALQARLQAVEKRFSGRIGVYLHHLGRNESL-SYHADEPWYLASGVKVPVAIAVLREVE +QGRLALDTRVRLQESDFVDGAGQTNSYPAGTLRVSFLLEQMIIHSDNTASDALIRTV-GL +DQVNSVATELLATNKLIVTSLSDVRRAYYATEVNTAPLSDFGRMLATLSDGLALNPEGTA +YLLNLMSRVKTGEQRIKARLPVASRFAHKTGTQHR-RVCDLGIVATPRQERVVIAACARG +GT--QAAGERALREIAAAVT--- +>[subseq from] Serine hydrolase n=2 Tax=Pseudomonas sp. TaxID=306 RepID=A0A3C1MKT8_PSESP +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +EQVNAITRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000D205452 +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +EQVNAITRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Candidatus Omnitrophica bacterium ADurb.Bin205 TaxID=1852852 RepID=A0A1V5X8F6_9BACT +----TAQLMREIDKFKGDSAVIIKDLESGWEF-VYQKDKLYPSASLAKIPIMAAAFIAAG +KGKVNLDTEIALKPSDKLTGSGVLKSLPAGTFNFERLIGFMIYDSDNTATNIVTKTL-GI +DYLNNTFKELGLKHTKLLRRVADYRLR-NQGVENYTTAEDMAFLLEKIYLRSLFNKQVSD +KCIGLLKLTRM-NDRIPRYLPADITIAHKTGLERN-VCHDVGLVLTPKGN-FLICVLTNY +KNTDLKTAKQFIARIALLTYKFy +>[subseq from] Serine hydrolase n=1 Tax=Cytophagales bacterium TaxID=2053541 RepID=A0A3D6ERG4_9BACT +-eETSQQLETILSKPKGTFAVAYKDLTTGEEI-LINEHLLFHAASTMKTPVMAEVYRQVA +EGKFSLKDSILIKNESILDGSTFSYDHIGEKRTVYSLMYDMIIISSNLATNLIVELV-DA +KNVTQTMRNMGANDIQVLRGVEDTK-AYEAGMNNQVTAYDLMLLFEKIDKEEIVNAEASM +AMMDILLDQKF-NDIIPAKLPADVKVAHKTGSIT-AVRHDSGIVFLPDGKKYVLVLLSKD +LE-DEQGGVQAMAEVSEVLYQY- +>[subseq from] CepA family class A extended-spectrum beta-lactamase n=6 Tax=Bacteroidales TaxID=171549 RepID=A0A679HPI5_BACT4 +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGNNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides dorei TaxID=357276 RepID=A0A4R4GF13_9BACE +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Uncharacterized protein n=1 Tax=Peptoniphilus harei TaxID=54005 RepID=A0A133PS82_9FIRM +--GLQNKIENIVEESSANISVSFYDLDLGEGF-SINGDKQVPSASMIKLLILLKSFDECH +EGKLNLEDTISLDDYERIDGSGILKELYRNHFSIRELLTLMIIVSDNTATNILIDLL-GR +EEINKIGHEFGLEKTILQRKMMDSLAK-ERGLDNFTSSNEILKLLKMIYVKNFVNEDYSE +LALDILLRQQE-RDRLQRFLPEDLKIANKSGDLDN-LENDGGIFFTKNK-NYILVVLVNQ +AE-SNVLAKEIIGEISLKIYK-- +>[subseq from] Serine hydrolase n=1 Tax=Psychrobacillus glaciei TaxID=2283160 RepID=A0A5J6SSG8_9BACI +--TLVNSILELIEQSDGTWGIVLEDLDLGEKW-VWNGDELFYAASVIKVPIMAAVFAAAE +MGKLAISDQLVLKSEDFVLGSGILQHLTPGTFSLKDIIMLMIIQSDNTATNIMIDLV-GM +DNIVQTLKKAGMEKSTFYNKLMMNNPNPK--GFNQITPNDISKLLKQMTTGELVSPEASE +QMIGIMKKQQI-KDCLPDKLPTAWELAHKTGWIP-GTRHDVGIFYVGQRK-LIATVLSKD +VD--DLLSKQILTEIGGKIYN-- +>[subseq from] Serine hydrolase n=1 Tax=Thermomicrobiales bacterium TaxID=2482790 RepID=A0A5C7JKA3_9CHLR +--AFAEAMADYVDDLSGEIGVAVRDLETGDTF-GYNATEIFPTASTLKVPLIYVLYRLAD +AGAIDLNERVTLSYANRVPGSGVLQHMDEGLPTLRDLAELMIIVSDNWATDLLWNRL-TK +PVVDSTLAEIGLTQTSLPFTIHEIFAMVYDARNDTSSPADMVRLLTLIDAGDGLSDVSRD +AVLDTLKHQNF-TTILQGRLPEGIEVAHKTGSLR-GVKNDVGLVSAPNA-RYAIALMSRG +QD-DIPEVTDRLSRISRWVYD-- +>[subseq from] Beta-lactamase n=2 Tax=Pseudomonas TaxID=286 RepID=A4VI24_PSEU5 +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDHLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +EQVNAITRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] Beta-lactamase n=4 Tax=Pseudomonas TaxID=286 RepID=S6JUA9_PSEST +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +DQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas stutzeri (strain ATCC 17588 / DSM 5190 / CCUG 11256 / JCM 5965 / LMG 11199 / NCIMB 11358 / Stanier 221) TaxID=96563 RepID=F8GZ31_PSEUT +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +DQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] Serine hydrolase n=1 Tax=Cystobacter ferrugineus TaxID=83449 RepID=A0A1L9BKP4_9DELT +---------RISQVKGATVAVAYQRLGSPDSL-YLEADRSFHAASTMKLPVMLEVFRQID +AGTLSLEEPVTLTHQSIVDGSPYVHERLGQPVPLRELVERMITRSSNLATNLVLSRV-DA +RRVTKTLRALGARRMTVLRGVEDAKA-HARGLNNTATARDLASLLSALERGRAASPASTR +AMRSILLAQEL-NREIPAGVPPGTPVAHKTGQIS-GVLHDAAIVYPPGHPAYVLVVLTSG +IP-DEAVARSLIVELSRQVYAH- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. HSS6-12 TaxID=2720024 RepID=UPI00143C0B86 +------QLAAIVDDAAATAGVTVRDLSGDQQI-AVNGTFRPKAASVIKLWILVELLRRVD +CGQVSLGDGVLVTPADVVDGTGELQHETFPQVTLHRLAEYMIIYSDNTAANVLIDYLGGF +APVNALIDSMNQRETILARKMLDTEAA-RRGEENYTSPDDVVSLLGAVWDADILAPPTRD +LMINFMRRQTL-NNKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-VAVAFLTGG +PI---ATGDEVVRRLARTVYDY- +>[subseq from] Class A beta-lactamase n=1 Tax=Fusobacterium sp. CM22 TaxID=936563 RepID=X8GUG7_9FUSO +-tEWKKEIEKIISQVEGKVCVNFYDLNRIDGF-SINGNEKVLSASMIKLLILAELLKKAS +ENKFSLSDTITITNFMKTEGDGVLKENIGHHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYFPSDIKIAHKCGDLDN-LENDGGIIWIGDR-IYILVVLTSG +MS--NLQCKQTIGKISKFIYDK- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7B5C82 +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +EQVNAITRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2G6HSG1_9BACT +-kDLDRQIKEILAGQPGVYSVSYRDLASGREW-HFNADDCMHAASTMKVPVMLRVFQKLE +RENKSLNDALRVHNSSIVDGSAFAYQFLGKNVPIEHLVRLMIIRSSNLATNILIDWV-DA +KKVTELMVELGARQTSVLRGVQDLK-AFEKDMNNTTTSRDMLQILISCYQSELFTKTSRD +AMIQFLLDQEF-NDLIPAGIPANAKVAHKTGSISR-VHHDAALVMLPDGSSYGLVVFSRD +FGEERERVKQTIRNISSAVYQY- +>[subseq from] Serine hydrolase n=1 Tax=Emticicia sp. 17J42-9 TaxID=2492393 RepID=A0A4Q5M1D2_9BACT +-----------------KVSMSVEGMSGEEFF-SYRPTVIVPSASVIKIPILMELMEKVK +AKQIDLNKVYILQASDKTGGSGVIANMPDGKFTIRELAQEMIRSSDNTATNILIREV-GM +EAVNQNLMRLGSTQTRLNRIMMDTMA-VKQGRENYVNTLEINDLLRKIYKKEVATPALCE +EMIEILKNCGD-TTTIPRNLPKDVVIAHKTGGLAY-VRGDAAIVYTK--EPFIISIFIEG +FKE-ESTAERIIGDLAEICWE-- +>[subseq from] Serine hydrolase n=1 Tax=Luteitalea sp. TaxID=2004800 RepID=A0A6A7L9E8_9BACT +---VADRIAALTKGFKGTVVFYAKNLNTGREL-ASDPDARVRTASTIKLPVLCALESLVT +NGKVKWDERLVLKPEEKVSGSGVLQSLAEGTLTVRNLAILMIIVSDNTATNLLIDRI-GA +DTVNDYLDTLGLTKTRLNRKIVSGDSENKRFGLGVSTPRQMVTLLERLHQGKIVSPAASN +DVIDILKKQQI-TAASGRHAPQQWTVASKSGSLN-ALRSDVGIIYTDAD-PIALAITVED +MPETDNVGEKLIWQLTEAL---- +>[subseq from] Beta-lactamase class A n=2 Tax=Pontibacter mucosus TaxID=1649266 RepID=A0A2T5YFS3_9BACT +-qQTEQQLAAIINRSPAVTGLVAVDLTNGDMF-SFNAEVVFPQASAIKIPVLMSMYKQAH +EGKFSLNDTRQVAAADAVGGTGVLKDLDGPPMSIRNLGILMITLSDNTATNTLIDLV-SM +QETNAMLRSLGAKHTLLQRRMINAAAS-GRGEENISTPADAAKILQLLYKGEFINKATSE +EIVSILSKTDRQTSRLAPGLPDNVPVAFKPGILN-GVSTEWAIVLLPER-PYVVAVMESY +KV--KGQAERTVEELSEVLYQYf +>[subseq from] serine hydrolase n=1 Tax=Paludisphaera sp. JC665 TaxID=2711216 RepID=UPI0013EA38D9 +--ELGARIEKLVKEHKGKATVALKNLKTGETF-SINPDEPMPTASLIKFPVMVEAYRQAA +EGKIDLNAPVTLRKKDMVPGSGVLTYHFSDGFPLVDAVHLMITYSDNTATNIVLDAV-GI +GSTAATMEKLGYPNTKIHSKVFRRDTSVFPDRSGSTTAGEMVKLFEALQAKKLVDEKSSE +AMWKHLLTCDD-KAKFPRFLPAGTKVAFKTGSVDE-ARTCAGVIETKGG-PVALCVMTNA +NEGDENAGNVLCAKTAREVYDYf +>[subseq from] Serine hydrolase n=1 Tax=Cerasibacillus quisquiliarum TaxID=227865 RepID=A0A511V2E8_9BACI +--TLIQQIEKTITDSNGEWGVVLEDLQTKETW-TYNEHEQFPAASIIKLPIMVAAFQAAE +DKILRLSDTYSLSHDDLVGGSGVLQHMTPGTITIHDLITLMIIQSDNTATNILIDLL-EV +DYIQKIMEDIGMHESEFYNKLMIVPVK--RKGANTITAKDVSHLLKQLVQGALVSEHACE +QMIEIMKKQQI-SDGFRGKLPSQWQLANKTGHITN-VQHDAGIFYVGYR-QLIATVLIKN +LE-D-YKANTSLMQLGETIYQY- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. polymorphum TaxID=76857 RepID=A0A2C6C9Z4_FUSNP +-tEWKKEIEKIISQVDGKVCINFYDLNKNNGF-SINGNEKVLSASMIKLLILAELMKKNS +ENKFSLSNTIMIANSMKTGGDGILKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYFPSDIKIAHKCGDLDN-LENDGGIIWIGDR-IYILVVLTSG +MS--NLQCKQTIGKISKFIYDK- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8QV74_9BACT +---LEGKVRGLIAASGATVAVAFRDLQTGREL-LLNPGVSFHAASTMKVPVMLEIYRQAQ +FGKLSLDERLPVKNESIADGSTFSYKKIGGTETVRELLRLMITESSNLATDILIERV-TP +ARVMELMRRMGARDMRVLRGVEDGK-AFERGLNNTTTARDLLVLMRAIAEERAVSIIASR +EMARVLLDQKF-NEGIPAGLPPLIPVAHKTGSITK-IEHDAGIVFLSGRKPYVLVVLVRG +IAE-EARAHKLIADISRAIYE-- +>[subseq from] serine hydrolase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=UPI0013A6351E +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPT------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A3B9TL01_PSESP +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRIE +QDDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +DQVNAVTRELVSEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STTQAERALRGTGEAVA--- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus chromogenes TaxID=46126 RepID=UPI000D4C05C2 +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVVSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDR----------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=filamentous cyanobacterium CCP4 TaxID=2107699 RepID=UPI000D12CC7F +---LKGELENLATLTPGTPVAFAVDLDSGQYI-DLGGAEPVAAASTIKVPILIAFLQQVD +AGTVALNQSLMLQEEYMAGGSGTLREAVGTEYTALDVATRMIVASDNTATNMMIAALGGI +EALNQTFAGWGLEHTVLRNPLPDLDGT------NTTSAKDMALIMALVDQGGLLTPRSRD +RLFSIMQRTEN-VSLIPSGISDRSLTAHKTGDIG-GLLGDVALVDVPNGKRYTLALLVQR +PTND-GRASELIRRMTETVH--- +>[subseq from] hypothetical protein n=1 Tax=Leptolyngbya sp. KIOST-1 TaxID=1229172 RepID=UPI00069115A7 +------------------PVAFAVDLDSGQYV-DLNGAEPVAAASTIKVPILVAFLQQVD +AGTLALNQSLMLQEEHLAGGSGTMREAVGTEYTALEVATRMIVASDNTATNMMIAALGGT +AALNQTFTGWGLEHTLLRNPLPDLDGT------NTTSAKDLALIMALIDQGGLLTPRSRD +RLFSIMQRTEN-ISLIPSGIGDKSLTAHKTGDIGS-LLGDVALVDVPNGKRYTLALLVQR +PTND-GRASELIRRMTEVVH--- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. polymorphum TaxID=76857 RepID=A0A2B7YH17_FUSNP +-tEWKKEIEKIISQVEGKVCVNFYDLNKNNGF-SINGDKKVLSASMIKLLILAELMKKIS +EDKFSLSDTIIMANFMKTGGDGVLKVLNTGHFTLKELATLMIIISDNQATNILIDFL-GM +ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Beta-lactamase n=2 Tax=Bacteroidales TaxID=171549 RepID=A0A5C6K354_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGHNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T0G8_9BACT +-----DHLARLERDHGGRLGVCVLDAGSGREL-HWRGDERFGMCSTFKLPLAATVLHAIR +AGELDGDEAIGFTQDDLVPHAPVIQSRLDAGMTPVELAQATQLTSDNVAANLLIRRLGGP +EAVTARWHAFGDAITRLDRWEPAMNLVPPGEIRDTTTPCAMARHVARL------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4V1ZP77_9BURK +--RLEKALAGIDAQGTAKIGVYVRDLDTGVAA-SWKADQRWYLASMVKVPVAIAVLRGVE +REQYTLDTKVSLRASDYVDGAGRTNSYKVGRLSIRFLLDQMIIYSDNTATDMLIDLV-GA +AGVNAVVESLVPDRFREITSLSDVRHAYYASGVNSAPLTAYADLLQLLADGKALTPRYTD +YLLKVMERVATGKNRLKAGLPPDMKFAHKTGTQRR-RICDAGLLRFAGRERRAIVVACVR +DEPSLVISEHALVQVGAAICK-- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0009906B5E +------------------------------------------------------------ +-----------------------LEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] serine hydrolase n=1 Tax=Cyclobacterium sp. SYSU L10167 TaxID=2666329 RepID=UPI001391CA1F +--ALEEGILSLMQATEGDFGMAFRMLDSGREL-LINEKEVFHAASTMKTPVMIELFKQAG +AGKFDLQDSILIVNESIVDGSPFSYERIGEKTTIYELMYQMIIKSSNLATNILIDLV-GA +EKVTQSMRELGAEDIEVLRGVEDLKA-FEAGLSNTTTALDMMLIMEAIALGNV---EGSE +EMVTILSDQYF-KDLIPKLLPADVKIAHKTGSIT-GVQHDAAILELPNGNRYVLVILSKN +LA-DVAAGKETIAQISRLVFEY- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=UPI000CCC3DE1 +-sKLEQTIQELAASIDGRVAVFIEW--DEGRV-SLNEQEAFPSASLIKIPIMLEALRQEQ +VGQTDLNTSLAIPAEERVGGMGVLADLSSEILPLRDLVTLMIAISDNTATNLVIQKV-TM +EAVNQLAAGLGCQHTVLARKMMDTEA-VRQGKDNYTSAQDIGLLLKEIITGDTLDSSRKE +AAFQMMRQQQF-HTKLPAELPPDASFAHKTGELA-GIEHDAGILKMGDR-YITMAVLTRD +LA-DEAAGREFIAKVGKAVFDTf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0N9HIS3_9BACT +-------FEKLEHWTAGRIGVAAVNTADNSSL-QYRGDERFPLCSTFKLMAAAAILHRSL +DEPDLLKKHILYSATEVTAYAPVTIKHLSTGMSIADLCAAAIQYSDNAGVNLLMKELGGP +KAVTAFAQTIGDNLFRLDRWEPELNSAIPNDPRDTSTPASTISGLYRL------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Parabacteroides merdae TaxID=46503 RepID=A0A3E4ZMR6_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGVNEAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=UPI0012922B96 +---LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGCNGAQNDVAYICLPNKVCYTLAVFVKD +FKGNESQASQFVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q5PTD4_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +GRVEAVRKALNLKTTDLKATIDEAYDRYYKTNVNSATLEAYGDMLEKLVKGQLLKPPSTQ +LLFTAMKIDIFTNYRLQAGLPRSEKFIHKTGTQYR-RACHVGVINPQNGADAIVVTTCAA +DLDEQKQAGRVFQQVGQAITK-- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium coskatii TaxID=1705578 RepID=A0A166SWV4_9CLOT +------KILAAIDLKKLNCAFVIENLKTGEKI-AYNENVVVPSASLIKIPIMMEILNQVK +EGKLSLKQRITVEDNVKVPFSILNLLESGNSYTLKDVITLMIIQSDNTAANILMDLA-GM +DNVNNYVKNLGIKNTVLQRKMMDSEAR-KEGRENKTTAAEMAKFFEIIYKGEKAKGSYSV +IMKNILTSQLD-NSVMRLNIPDDTLIAHKTGDLD-GISHDAGIVYLPNVD-YIFCGLTWD +AV-TNNFARETIGKISKIAYDYf +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides eggerthii TaxID=28111 RepID=A0A414M273_9BACE +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADYNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Halomonas sp. 141 TaxID=2056666 RepID=A0A2M9TDX4_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +------ARTLGVSPSSFAQDYDSAFDAYEASGENVGTLRAYGDLLASLHHGGMLDREQRQ +TLLEVMQRTRSGEQRLKRGMGREVTFAHKTGTQHR-RSCDAGIATRDGAQHWVIVACSRG +PL-ALSAHEQALTRVGEALHD-- +>[subseq from] Class A beta-lactamase, subclass A2 n=6 Tax=Bacteria TaxID=2 RepID=A0A641QV39_BACOV +---ISDSISKIASEYPGEIGVAVI-INNQDTV-TVNNKSIYPMMSVFKVHQALALCNDFD +KKGSSLDTLVKINREKLDPWSPMMKDYSTPVLTVRDLLRYTLIQSDNNASNLMFKSMLNT +AQTDSFIAKIPRSSFQIAYTEEEMLADHDKAYSNYTSPLGAAVLMNRLFTESLISDDKQS +FIKNTLMECKTGMDRIVAPLKEGVVIAHKTGSGFNGAHNDVAFIRLPHNKYYTLAVFVKD +FKGNETQAAKIIARISNTVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Chryseolinea soli TaxID=2321403 RepID=A0A385SNN0_9BACT +hdKVKETITQALAAQQGTFAVAFKDLSTGEEI-FINERMPFHAASTMKTPVMIEVFKQAA +AGKFSLTDSVLIKNESIVDGSPYGYRQIGKKRTLQSLVYEMITVSSNLATNIVIEWV-DA +KNVTQTMRDLGAKDIQVLRGVED-NKAFEKKLNNTVTAYDLMLIFEKLGKGEAVNPEASK +AMIAILLDQKY-NDIIPAKLPRDVKVAHKTGWIK-GLHHDSALVMLPDGRQYVLVLLSKD +LK-DEKAAVETLNDVSKTLYDY- +>[subseq from] serine hydrolase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013A62298 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPT------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T354_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQEISLDALCGATMRTSDNTAANKVLEALGGP +DAVTAFMRAMGDEVTQLDRWETELNEATPRCRR--------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Psychrobacillus vulpis TaxID=2325572 RepID=A0A544TRP1_9BACI +-kKLISKIQDLIGQSEGIWGIVLEDLDLGEKW-ELNGEELFYAASVIKVPVMATIFSAVE +RGELTLTDQILLKEKDFVGGSGVLQHFTPGTLPIQDIIMLMIIQSDNTATNILIDLV-GV +ENIVRTMNEAGMEKSTFYNKLMMNNPNPK--GFNQVTASDIARLLKLIASGELVSSEASE +QMISIMKKQQI-KDCLPEKLPSPWELAHKTGWIP-GTRHDVGIFYVGQR-RLIATVLSKE +VD--DLMSKRILSEIGEEIYNY- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=UPI00125F6D87 +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGNNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella denticola TaxID=28129 RepID=Q8KT56_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQVLALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Lysobacter alkalisoli TaxID=2591633 RepID=A0A514BSS8_9GAMM +------------------------------------------------------------ +-------------------------------------------------------AAAGP +TRMHRLAELLGVTPADFHPDIDSAFEAYYATHVNTAPLRDFGRMLVTVANGLALGQEGTT +YLLDTMTRAKTGEKRIKAGLPPEARFAHKTGTQHR-RACDLGIVLMPAGEQVVIVACVRG +PA-SVAQSERALREVGAAVT--- +>[subseq from] Beta-lactamase class A n=1 Tax=Salinimicrobium sediminis TaxID=1343891 RepID=A0A285X1Y8_9FLAO +-qKTEQRLQEIFNTSPAITGLVAVDLTSGEKI-GWNSEVQFPQASSIKIPVLMEVFKQAH +EGKFSLSDPLPLTSENTVGGTGILKHLEDPALSIKNLGILMIALSDNSATNALIDLV-GM +SEVNSTLKSLGMTNTLLQRKMMNSEA-SARGEENLATPADAAKILQLLYKGEFVSPEVSN +EILDILKMTDREDSRLAAGIPENVPIAFKPGFIS-GVSTEWTIVLLEQR-PYAVALMESN +KLP--GEAERVMEEVSEILFNYf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0N9HJB5_9BACT +------------------------------------------------------MLSEID +KGSFRLIKRSRSRKSELLPSSPIREKYPDGALTIAEILEYTVSKSDNAGCDALLRLLGGP +QAVENYFVKNKFKDIAIKINEEVMQGNWDLQFQNWTTPKAADKVLEAFYSNKLLSQKSYA +FLWKVMRETETGANRLKGQLPDGTVVAHKTGWSGTAAVNDIGVVFLPDGKHFFISVFVTD +SRENAETNEKIIADIAKAAWDHf +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0009908747 +------------------------------------------------------------ +-----------------------LEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGN +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase AmpC n=1 Tax=Marinobacter sp. HL-58 TaxID=1479237 RepID=A0A0P7ZGI0_9ALTE +-eDLEKKLAGIDDRYPGELGVYVHNLEDGKTA-DLRAGETWYLASTIKVPVAMAVMEAVD +SGELTLDTDVELKAADFVDGAGETNKSPGDRVSVRYLFEQMLTHSDNTATDVLIRLV-GM +DAVNQLVRRYTDGGIGEVTTLADVRRGYYESGLNSGRLDEFSLLFEALAEQDGLSDDSSA +YLLSTLENIKTGDNRIKAGLPDHVTFIHKTGTQYR-RACNIGLVQMDDHPGVIIAACGRG +TQ-DLNASELAFRRVGEAVSE-- +>[subseq from] serine hydrolase n=1 Tax=Salegentibacter sp. Hel_I_6 TaxID=1250278 RepID=UPI00056D216F +-eKLQQKIDSVFENTQGDFAIAFKNLSEEKDSiFINAHEDFHAASTMKTPVMIEVFKQAA +EGKFSLQDSLVIKNESILDGSSYAYERIGQKRSIQDLVTDMIIYSSNLATNIVIELV-DA +KNVNKTMRELGAKNINVLRGVEDMK-AYEAGLSNSTTAYDLMLIFEALSNGKAVNPEADK +QMLEILQQQKH-IDLIPALLPENLKIANKTGWIT-GVHHDSALIELPDGTKYVLVLLSKN +ME-NMDAGTKMLAEVSKMVYDH- +>[subseq from] MurNAc-LAA domain-containing protein n=1 Tax=Balneolaceae bacterium TaxID=2053516 RepID=A0A5Q4FF58_9BACT +--TLEQQILRITEAAEGDYAVAFIDAGNPETNlFIDADEWFHAASTMKTPVMIEVYRQAM +EGRFGLDDKLVVRNEFVSIGSTYSYDHLGSELSIRELVYSMIVRSGNLATNIVIEHV-GA +ENVNRAMADMGAEGIRVLRGVEDMEA-FRAGMNNEVTARGLAMMYLRLAEGSVLDETYRS +QVLSVLKDQHF-RDMIPALLPEGVTVAHKTGWIT-GVRHDSGIVYLPDGRAYVLVILSKN +VP-DRADANRTGAEISRRIYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus yeomjeoni TaxID=291403 RepID=A0A327PTY7_9BACT +-qMLQSTIQAQLDSIQGDVAVAFINLSDPSDSlFINASEEFHAASTMKVPVMIELFKQQK +QGKLDLNDSILLKNESIVDSSLYSYNKIGGKVTLKDLMYPMITVSSNLATNVLIELV-GA +KNVTATMRDLGAEKIEVLRGVEDQK-AYDLGLSNSTTAKDLMVIMKAIAEEKAGTKQDCD +EMIRILKDQQF-NEIIPFYLPKDVTVAHKTGSIT-GVHHDAGIVYLPDGRSYVLVLLSKN +LE-DFDKGTEQLAGISKTVYDH- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI0013FD88FC +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPT------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A3E0NVQ3_9BACT +---LRGDVEALIEASGAEVAVAMRTLDGALEL-LIEPDLEMHAASTMKVPVMIELFRRAE +QGELTLADPIEVTNESIVDGSPYTYSAIGSERTLRHLCEAMITWSSNLATNILIDFL-GA +ERIQATTDELGASGMKVLRGVEDIKA-FDAGLSNSTTARALLVLLEKLGRGEVVSADASE +QMVAILRRQQF-GEAIPAGLPPGTVVAHKTGNITR-IHHDAALVEIE--RPYVLVVLVRG +IE-DRAQSAALIASIARRVH--- +>[subseq from] serine hydrolase n=1 Tax=Cyclobacterium marinum TaxID=104 RepID=UPI0011EF141E +--QLEEEIRKLMNETEGDFALAFRSVDGEESElFFNEKETFHAASTMKTPVMVALFEQEA +AGKFSLQDSILIRNSSILDGSTYQYKRIGENATMYELMYEMIVRSSNLATNILIEKV-GA +KNVTQLMRELGAEDIQVLRGVEDLK-AYEAGLSNTTTALDMMLIMEAIAKHKV---AGSK +KMIDILSDQHF-NDLIPKYLPKEVKIAHKTGAIT-GVQHDAAIVELPDGNRYVLVILSKN +LT-DEKAGKECIAKISQMIYN-- +>[subseq from] serine hydrolase n=1 Tax=Halomonas stevensii TaxID=502821 RepID=UPI0012EAF5B4 +------------------------------------------------------------ +------------------------------------------------------------ +----ALARTLGVSSSSFAQDYDSAFDAYEASGENVGTLRAYGDLLASLHHGGMLDREQRQ +TLLEVMQRTRSGEQRLKRGMGREVTFAHKTGTQHR-RSCDAGIATRDGAQHWVIVACSRG +PL-ALSAHEQALTRVGEALHD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A650AIC6_ECOLX +------------------------------------------------------------ +----------------------------------------------------------GP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDITVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLAS--------- +>[subseq from] Uncharacterized protein n=2 Tax=Cytophagaceae TaxID=89373 RepID=U5BJI8_9BACT +--ELESALLAELENAQGDFAIAFKTLDDPSQMvLINEKEVFHAASTMKVPVMIEMYKQAG +QGKFSMKDSIPIINESIVDSSLFSYERIGQQATYYELMYEMVTMSSNLATNILIEKI-GA +DNINATMREMGVLDNQVLRGVEDLKA-FDAGLNNTTTAYDLMLIMEAIAKGETVDSASSE +EMMDILIDQKF-NEMIPELLPKDVVVAHKTGAIS-GVEHDAAIVKLPDGRAYVLVILSKN +LE-DVEKGKSQIAQISKIIYEY- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Omnitrophica bacterium 4484_49 TaxID=1970784 RepID=A0A1W9RGE6_9BACT +-----NEVDEVLKKFKGKAGVVIVDLQNGWTI-ARNQNEKCPAASVIKLPIAVVVYKAIA +EGKVFRGQVIEIRRSDVVSGSGVIRKRNPRRYTLDDLVALMLTVSDNTACNKIISLL-GF +DYINTEMKKLGLQDTTLRRFMMDFKAR-DRGFENFTSARDIAEVWKLLYYEKILGEKESR +YLIELLKNQKV-NDRISGLLATRTIVANKTGLERN-VCHDSGIIFTPYGD-ILIVVLASD +FK-SFKLAKEFIATLA------- +>[subseq from] serine hydrolase n=1 Tax=Rubrobacter indicoceani TaxID=2051957 RepID=UPI000E5A1082 +------EAARTVEEYPGVAGFYVMDPKDGSGY-GVRPDEEFFSASTIKIAVMAAVYRKIE +SGELEYSDMLTTTEGDWAAGAGWLRWNTPGATTVEDALWLMMTESDNVATNVLLRTVGGP +EYVNSVSRDLGAENTNLFWKLSSERAAVP-ELDNRTTPRDMATMLAAIYSGDGLNDFSRN +EMIDLMRQNSL-EYWLEGGIPGGVTAANKGGWQD-GIYNDAGIVERD-GSPYVLAIYTMN +GP-ELEVGSPVLAEISGSVW--- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5RVY2_9BACT +-kKLETRVEEIASSLDGVMGVAILDLTGGRIL-LRNADRVFPAASSIKIAILLELYRQDQ +KGKAKLDDIYTFDPKDLVEDSRIMAGLTAGVITNRDLAQFLVAVSDNAAANVLYDRV-GK +DNVNAMLHSLGLPKTLLRRKMMDIAAARRG-DENIATPQEMVRLLEAIFKEKALDKQATA +EFIKQLSTLKQ--SYLPRYVPESVQVANKPGELE-GVRTDSGIVFAQNQ-PFAISVMTAY +DR-DEKAAERAIGEVALEAYRYf +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7B7544 +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRIE +QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +EQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STAQAERALRGTGEAVA--- +>[subseq from] B30.2/SPRY domain-containing protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9JZZ7_9BACT +---LALEMAKLAREFDGALGVYAKELNGGKEF-AYHADDPFATASLFKLPVMVELFRRVE +AGEVSFAKRLKPPETGISRGTGLIRSLKDQPFTLRDYCRLMIIFSDNIATDTLMQII-TP +QSVTATMKELGFPHTRVSGNCTLMHYADRSLNGNVTTPREIGLLFERLYRGQVVSSSASA +QMLEILKETTS--RKMASSLPSVIEVAHKVGSTK-GVSTDAGIIYMPKK-PIVLSLFTYS +ETAD-ARAGKLIADIGKLVAEEf +>[subseq from] Beta-lactamase class A n=1 Tax=Paramaledivibacter caminithermalis DSM 15212 TaxID=1121301 RepID=A0A1M6LHN7_9CLOT +---LRKKIDDIIEGVDGDVGVIVKNLETNESI-MINEDTVFPAASVIKLYILWELFERIK +KGEFTLEQEILLKESHKVGGFGVLKEHEGINLSLKDIATLMIILSDNTATNILIDLL-GM +DNINQTIKNNKMKDTVLQRKMMDGEA-KAKGFDNYTSPMDVLSILEKSL--------QRE +EIIDIMKRQQC-NNKLPALIDDSIVIAHKTGDLP-AVEHDVGIMFMENS-SIIIIVLTKN +LKEN-IEGIKLNNNIGKAVYDYy +>[subseq from] serine hydrolase n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=UPI0007C80ADD +----ERQVERRILAAHADVAVFFRPLGGGSEW-SYKPDDTFHAASTMKVPVMIELFHQAR +QGKLALDDPLLIHNESLVDGSAFYYRSEGQTRTLRELCELMITMSSNLATNLLIKKL-GI +ENIRATVHLLGADGMNVLRGVED-NKAYDLGLNNTTTARGLAILLTAIAQGKVVDPDSSR +QMVEILKRQHI-NDGIPSGLDPTIPVAHKTGTLK-GIHHDAAIVY--GRQPFVLVILVRG +MTNS-EDSSALMADITRVFYR-- +>[subseq from] Beta-lactamase n=1 Tax=bacterium J10(2018) TaxID=2320122 RepID=A0A3L7ZYW6_9BACT +---LADTITKITSQYPSEIGVAVI-INNTDTV-TVNNSNIYPMMSVFKVHQALAVCHDFD +RKGLSLDSLMNIAREELDPWSPMMKEHLEPVLTVKDLLHYTLSQSDNNASNLMFKRLVDV +ARTDSFIATIPRSSFHIAYTEEDMSTDHDKAYANCTSPLGAAILMNRMFTDSLVSRENQL +FIANTLKECKTGNDRIAAPLKEGISIAHKTGSGYINAHNDVAYICLPDNTCYTLAVFVKD +FKGNEAEAAKAIAHISATVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534GHI7_9GAMM +------RIESVIERSGADVAVAFRTLDGRTQW-LRRADEPFHAASTMKVAVLIELYRQAR +QGRVGLDDPLRVKNESLVDGSAFAYRAAGGTRTLRELSELMITVSSNLAANLLMDKL-GV +ENIRAGVHALGADGMNVLRDLEDAK-AFERGLVNTTTAQALLALLDAIARGQAVDRESSR +QMLETLERQTI-NDAIPAGLPAGTHVAHKTGDITR-IWHDAGIVLA--RRPFVLVVLTRG +LEN-PKESTALIAEITRELYR-- +>[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534CTH2_9GAMM +------RIESVIERSGADVAVAFRTLDGRTQW-LRRADEPFHAASTMKVAVLIELYRQAR +QGRVGLDDPLRVKNESLVDGSAFAYRAAGGTRTLRELSELMITVSSNLAANLLMDKL-GV +ENIRAGVHALGADGMNVLRDLEDAK-AFERGLVNTTTAQALLALLDAIARGQAVDRESSR +QMLETLERQTI-NDAIPAGLPAGTHVAHKTGDITR-IWHDAGIVLA--RRPFVLVVLTRG +LEN-PKESTALIAEITRELYR-- +>[subseq from] Uncharacterized protein n=2 Tax=Planctomycetales bacterium TaxID=2053591 RepID=A0A5K7XDI2_9BACT +-qQMQARLQAIADGVDGTFGLVVEDLAGEHAF-AVNSGRHFTQASCIKTPILMEVLKQAH +EGKFALTDRVRVEQQDKTTGSGVLFELGNGSLSIEDLCVLMILLSDNTATNLLIDRV-GM +ENVTATMESIGCGQTVLRRRMMDMAAA-ARGEENRSTPADAARIMRLLKEGKFVNQAVSD +HALAILRKSKSG--AIRSTVPLSVPVPFKPGELP-GLLTEWALVELPERPYIVIAMGTYN +PKSTDDDLDAAMKLVGKEAYKFf +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas songnenensis TaxID=1176259 RepID=A0A482U6N6_9PSED +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRIE +QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +DQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STAQAERALRGTGEAVA--- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. SAJ1 TaxID=2497750 RepID=A0A3S0N9P3_9BACI +-------------TTGGTWGIYLEDLDKNETW-SWNENEVFYAASIIKVPIMAAVFSAFD +EGLFKLSDTIVLKREDLVEGGVLQHLTPGIRLTIYDYLTLMIIQSDNTATNVLIDLV-GV +KKIQEMIAEIGMKNSCFYNKLNTVPVK--TNGRNMITARDMAVLLKKLTSGMIISQYACE +QMIDIMKKQQF-RDCLPYKFPETWEFANKTGWVT-GIRHDIGVLYVGRR-TMNIVVLSKD +VE--DKLAKQTMAQIGECIFNY- +>[subseq from] Serine hydrolase n=1 Tax=Runella sp. HYN0085 TaxID=2259595 RepID=A0A344THH1_9BACT +--RLKEAIQAKLSGIEGNFGIAFKDLQSNQTL-FINEKENFHAASTMKTPVMIEVFKQAK +EGKFKLTDSILVKNESIVDGSTFSYKMIGKKMTIYDLTYQMIIVSSNLATNILIDLV-DA +KKANATMRDFGAKDIQVVRGVEDSK-AFQLGMNNSVTAYDLMVIFEKIARKKAIDRTSSE +GMTDILFDQKF-NEIIPAKLPKEVKVAHKTGSIT-GVQHDSGIVFLPDGRKYVLILLSKN +LK-DPKAGVRTLADVSEMIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=A0A3P1VRG0_FUSNU +-tEWKKEIEKIISQVEGKVYVNFYDLNKNNGF-SINGDKKVLSASMIKLLILAELMKKIS +EDKFSLSDTIITANFMKTGGDGILKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKETSQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] Beta-lactamase n=1 Tax=Fusobacterium nucleatum subsp. animalis 11_3_2 TaxID=457403 RepID=F7L0T3_FUSNU +-tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGNKKVLSASMIKLLILAELVKKVS +ENKFSLSDAITVTEAMKTGGDGVLKELNSGHFTLKELTTLMIIVSDNQATNILIDFL-GM +ENINLLGKELRLKETFLGRKMMDAEA-RKKGYDNYTCADDISLLLKLIYQEKLINKEASQ +LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENNGGIIWIEDKA-YILVVLTNG +MP--NLQCKQTIGKISKFVYDK- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella sp. ICM33 TaxID=1161412 RepID=UPI000684045F +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase n=2 Tax=Prevotella TaxID=838 RepID=F0H4M5_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella salivae F0493 TaxID=1395125 RepID=U2MSJ8_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase class A n=2 Tax=Hazenella coriacea TaxID=1179467 RepID=A0A4R3L531_9BACL +-qTLKARLNQWHEKAVGQWGIWIEDLADQQTW-TVNEDQTFYAASVIKVPIMVAVYQQAW +KGQFSLEEKIPLTKEMQVGGSGVLQHLSVGTLSIQDLITLMIIQSDNTATNLLIQLV-GK +KTIQQVMKDLGMEQSAFYNPLMIVPV--EREGVNLITAADVAACYRKIAKGEAVSYHHSL +QMIHVLKNQQI-QDCFPSQLPAPWELAHKTGMINR-VLHDTGILYLRDRA-FLLVALSAD +CS--YEEARQQLGELARIVWEVy +>[subseq from] Beta-lactamase n=2 Tax=Lysinibacillus TaxID=400634 RepID=A0A0A3I7H8_9BACI +-----EKIRPLVEEVDFKVHLFLKEMESEQFIlSENLDDGFSSASLIKVPILVAVLDYIE +QNKLSLYSELKIHSQNKVDFSVVTEQDLDE-CTLYELLVWMIITSDNSATNVLIDFI-GM +EKLNVYFNRIGLKATKLQRKMMDFER-LQQGYDNVTNARDMAYLFTSIYEQTLLSEQYSN +LVLDILSRQRV-HEGLKRYISGDVQMAHKTGSLDS-VFHDTGIVYLDSKD-YIIGVFTTQ +LS-DVEAGKRLIGRISKIAYEYf +>[subseq from] Beta-lactamase class a n=2 Tax=Leptolyngbya sp. Heron Island J TaxID=1385935 RepID=U9W143_9CYAN +-----------------TPTIYMFDLDTGNYV-DVAGNAEVAAASTIKLPILVAFFKAVD +DGRITVDQTLAMQSSQIAGGSGDMQVQPPGTYTALEVATQMIINSDNTATNMMIDLLGGA +PELNQQFASWGLTMTVLRNPLPDLEGT------NTTSAQDLVRMLAHLHKGEILSLRSRD +RVMNILQRTYN-KKLLPAGVSETTVSYNKTGDIGS-VLGDVALMDLANGKRYAIAALVQR +PEND-GRARELIRRISQTVYQ-- +>[subseq from] Serine hydrolase n=1 Tax=Limnothrix sp. CACIAM 69d TaxID=1890733 RepID=A0A372DP46_9CYAN +---LSDQFQKIAARYSLILHAAALDLDTGDFA-AWNDTRSVAAASTIKVPILVAFFQDVD +AGKIRLDEMLTMEARFVAPEAGTMQQKPGQKFSAIDTARQMIVISDNTATNMIMARTGGS +GPLNQRFQSWGLQGTNIRDLLPDITGL------NRTTARDLVQLTALINRGELVSIRSRD +RLLSIMRGTAA-NSLLPKGIGKGGEVAHKTGTLAK-LLADTGLVDTPNGRRYGIAVLAER +APND-PKAAEAIRDYSRAAYNHf +>[subseq from] Serine hydrolase n=1 Tax=Terrabacteria group bacterium ANGP1 TaxID=2569760 RepID=A0A537JDF1_9BACT +---LQGVVEGAAARVSGRLGCCVCP-ETGTPWaIHRAEETFATASVIKAPIAVAVAAEVE +AGRLEWNQLLPPHLRDDAGDSGVIRHLSPLPYTVRDLVFLMLVVSDNRATNLLVDLV-GM +ERLNASFARAGWERTSLARRLGDFEAR-ARGLENRSTPRETCDVFLRLLRGDLLSPGSRT +LLLEFLKAQVY-RDRLPARLPRTTAVAHKTGDMP-GVENDAGVLYLPAG-PIVAAVFTNE +LA-SDVEGRLAIQEIGRAIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Blastopirellula cremea TaxID=1031537 RepID=A0A368KK79_9BACT +----SALLLPLIEKHRGDVGVVIQHFPSGESF-AYQADKPMSTASLIKLPLLMATYAKVH +DGGVSLDTMITLTEADKVPGSGILTKHFSPGLSLRDAIQLMVAYSDNTATNLVIDTV-GL +DTTNTLMKKLGCDETRLNSKVFRRDTRSKAFGLGSTSANDMQRMLRALHDRSFVDQATSE +QILKHLYDCED-RMKAARYLPANVKVAHKGGSVN-AARTDAGIIDLPDGGAILFCVLTMN +NQTDDNEGDVLSAKIGKAVYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Omnitrophica bacterium TaxID=2035772 RepID=A0A660WPM8_9BACT +--NLKREILDLTTSFEGEISFLVKKLRFPSKI-SSREELIFPAASLIKLPLVAVALKAIG +EGKISSQEYITIKKEDIVGGSGIIKKMKTPFVHFERLCELAISYSDNTATNKIIDIL-GF +DYINENFKKIGLKNTFLERKMMDFRKR-SRGIENYTTTLDITYLLEKIYRGGILDKDASK +VLLSFLKKQKV-RDRLPRYLPKEIIVAHKTGLEK-GVVHDAGIVFTSRGD-YIICVLTKG +VK-NYERAKKIIAEISLLAYTFy +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Omnitrophica bacterium TaxID=2035772 RepID=A0A496S9Q2_9BACT +--NLKREILDLTTSFEGEISFLVKKLRFPSKI-SSREELIFPAASLIKLPLVAVALKAIG +EGKISSQEYITIKKEDIVGGSGIIKKMKTPFVHFERLCELAISYSDNTATNKIIDIL-GF +DYINENFKKIGLKNTFLERKMMDFRKR-SRGIENYTTTLDITYLLEKIYRGGILDKDASK +VLLSFLKKQKV-RDRLPRYLPKEIIVAHKTGLEK-GVVHDAGIVFTSRGD-YIICVLTKG +VK-NYERAKKIIAEISLLAYTFy +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Omnitrophica bacterium TaxID=2035772 RepID=A0A496RI38_9BACT +--NLKREILDLTTSFEGEISFLVKKLRFPSKI-SSREELIFPAASLIKLPLVAVALKAIG +EGKISSQEYITIKKEDIVGGSGIIKKMKTPFVHFERLCELAISYSDNTATNKIIDIL-GF +DYINENFKKIGLKNTFLERKMMDFRKR-SRGIENYTTTLDITYLLEKIYRGGILDKDASK +VLLSFLKKQKV-RDRLPRYLPKEIIVAHKTGLEK-GVVHDAGIVFTSRGD-YIICVLTKG +VK-NYERAKKIIAEISLLAYTFy +>[subseq from] Uncharacterized protein n=1 Tax=Pontibacter sp. S10-8 TaxID=1797110 RepID=A0A1Q5PHW7_9BACT +-qQTEKQLHDIISRSPAVTGLVAVDLTSGDTF-AFNPDVVFPQASAIKIPILMNVYQQAH +EGRFSLTDIRKVSPADVVGGTGVLKDLKTMPTSIYDLGVLMITLSDNTATNSLIDLV-SM +KEINAMLRGLGAKQTLVQRKMINAAAS-GRGEENLSTPADAARILQLLYKGEFISKATSK +EIISILKRTDRQTSRLAAGIPDAVPIAFKPGVLN-GVSTEWAIVLLPER-PYAVAVMESY +KV--KGQAEETVEQLSEVLYQYf +>[subseq from] Beta-lactamase class A n=1 Tax=Leptolyngbya sp. PCC 7375 TaxID=102129 RepID=K9FLX9_9CYAN +---LKTKLEELQELIELTPTIYVFDLDTGNYV-EVAGNAETPAASTIKLPILIAFFKAVD +EGRITVDQALAMQSNQIAGGSGDMQGQPPGTYTALEVATQMIINSDNTATNMMIDLLGGP +QVLNQQFVDWGLTMTILRNPLPDIEGT------NTTSAQDLVRMIAHLHKGDILSLRSRD +RVMNILQRTYN-KKLLPAGVSETTISYNKTGNIGE-VLGDVALMDLANGKRYAIAALVRR +PEND-GRAQELIRRISQAVYQ-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Prevotella intermedia TaxID=28131 RepID=C1M2W2_PREIN +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNVSYTLAVFVKD +FKGNESQASQYVAHISAVVY--- +>[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534FCD3_9GAMM +------AIESTIKKSGADVAVAFRTLDGRTQW-LRRPDEPFHAASTMKVAVLIELYRQAR +QGKLKLDDPLSVKNESLVDGSAFALYRAGPGRSLRELSELMITVSSNLAANLLMDRL-GV +ENIRAGVRALGADGMNVLRDLEDAKA-FEQGLVNTTTAQALLTLLEAIARGQAVDRESSR +QMLETLERQTI-NDGIPAGLPAGTRVAHKTGDITR-IWHDAGIVLAS--RPFVLVVLTRG +LEN-PKESTALIAGITRELYR-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Omnitrophica bacterium TaxID=2035772 RepID=A0A660WMK1_9BACT +-----NEVDEVLEKFKGKAGIVIVDLQNGWTI-ARNQNEKCPAASVIKLPIAVVVYKAIA +EGRVSRGQVIEIRRLDVVSGSGVIRKRNPQRYTLDDLVALMLTVSDNTACNKIISLL-GF +DYINTEMKKLGLQDTTLRRFMMDFKAR-DRGFENFTSARDIAEVWKLLYYEKILGEKESR +YLIELLKNQKV-NDRISRLLATRTIVANKTGLERN-VCHDSGIIFTPYGD-ILIVVLTSD +FK-SFKLAKEFIATLAF------ +>[subseq from] FRAMP1.1 beta-lactamase n=1 Tax=Prevotella sp. CAG:1124 TaxID=1262920 RepID=R5KV81_9BACT +-qTTEEKITDIINGKPAKVGVAWIV--DGKEH-SVNNADCYPLMSVFKLHGAIAALRQME +RRGTPTDTLVRINASQVTRYTPMLERYPESGIRFDSLLQYSVAESDNNACDIIISMAGGI +EDVNAEMCAIGLADYSLSETEISMQADPMRSYDNCSTPLSVAILFKKLFEENILGEPYAT +LLKHILISTTTGQDKIKAALEPGMLIAHKTGTGFDGADNDAGVVLLPDGRRIYISALVKD +SKLGSKENAKLIADMARIIIR-- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella sp. P5-108 TaxID=2024225 RepID=UPI000B9712BB +---LTDSISQIVSACPGEIGVAVI-VNKKDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] serine hydrolase n=1 Tax=Halomonas sp. BC2 TaxID=1670449 RepID=UPI0009C0032C +------------------------------------------------------------ +------------------------------------------------------------ +----ALARTLGVSSSSFAQDYDSAFDAYEASGENVGTLRAYGDLLASLHHGGMLDREQRQ +TLLEVMQRTRSGEQRLKRGMGREVTFAHKTGTQHR-RSCDAGIATRDGAQHWVIVACSRG +PL-ALSAHEQALTRVGEALHD-- +>[subseq from] Class A beta-lactamase n=2 Tax=unclassified Muribaculaceae TaxID=2006847 RepID=A0A3N2KNW8_9BACT +--RLQNELTSFVERKDARIGIAVI-INGKDTV-SVNGSKDFPMMSVFKFPLALAVAKWVD +SNGMSLNDSIAFGPKALIKYSPMLKKYGSGLMSFKELLEWSLIESDNNAADLLLKRVGGT +ACATTLLKDAGELDITIGASEQEMHKDPYTSYLNRSTPLAMATLFDRFDTDIKARSKSFS +NISVMLEQCRTGVDRLAAPFATNAVVGHKTGTGFISAINDCGYIHLPNGTRYTIAVFVAD +SGYDMTETSKIIADISEIVFK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Echinicola vietnamensis (strain DSM 17526 / LMG 23754 / KMM 6221) TaxID=926556 RepID=L0G3T4_ECHVK +-eTLRNQITAHLSEVQGDFAVAFRSLGSDTLSlMINEKESFHAASTMKTPVMIELYKQVA +LGNISLDDSITVVNESIVDGSPFSYGKIGQKSTYKALNFQMITMSSNLATNILIDKL-DA +KKVTQTMRDLGAKDIEVLRGVEDLK-AYEQGLSNTTTAYDLMVIMEAIAAGKAVSKEASA +AMFEVLKAQHF-NEIIPGLLPENVTVAHKTGSIT-GVRHDSGIVELPSGERYVLVLLSKN +LKAP-EKGIQVMAQISKLIYK-- +>[subseq from] serine hydrolase n=1 Tax=Acidaminococcus massiliensis TaxID=1852375 RepID=UPI0009F53543 +---------------AGPAQVYFTNLATNQSI--YLGSETMPSASMIKVFILAKAYEDIQ +DGRLSRKETFTLTSDNVVGGAGVLQGRGYGSVPLQEALELMITESDNTAANLLIDRL-GM +DRINAYMQSHGYTHSVLRRKMMDTE-AMEAGRENLTSTRDIALLFKRLYQGKCVGPAQDR +EMLAIYKRQTD-NDSIPGDLPQGTVVAHKTGEVND-LRHDGGIVYTPKGA-YVLVIFTRD +YTPY-----GTMAELSEKI---- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=39 Tax=Bacteria TaxID=2 RepID=A0A630ZBQ7_SALET +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=unclassified Prevotellaceae TaxID=224765 RepID=UPI00094E81AD +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella salivae TaxID=228604 RepID=UPI0005673B24 +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. P4-51 TaxID=2024228 RepID=A0A255UGR8_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase n=1 Tax=Thermobaculum terrenum (strain ATCC BAA-798 / YNP1) TaxID=525904 RepID=D1CF14_THET1 +--SLQERIANIIDSV-GYFGVAAKDLTQGREL-FINADETFNTASVIKVPIMIELFRRVY +EDNVSLDDRLILEDRFRTGGSGILKEFRSGLLTLWDLCVAMIALSDNVATNMLIDYL-GI +DAINRCMDSLGAHNTRLHRMV-GFKSIKPDQPKGRTTPRDMMMIFQKLAEGNVISESASE +EMIAILAKQHD-RNMIPRLLPDSAIVANKTGAVD-GVRNDVALIRFADGRQWVICILTKD +LRKVDHEGEIAIAKIALEIYKEw +>[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534IKU6_9GAMM +------RIESVIERSGADVAVAFRTLDGRTQW-LRRADEPFHAASTMKVAVLIELYRQAR +QGKLKLDDPLSVKNESLVDGSAFAYRAVGATRTLRELSELMITVSSNLAANLLMDKL-GV +ENIRAGVHALGADGMNVLRDLEDAK-AFERGLVNTTTAQALLALLEAIARSQAVDRASSR +QMLETLERQSI-NDAIPAGLPAGTHVAHKTGDITR-IWHDAGIVLA--RRPFVLVVLTRG +LEN-PKESTALIAEITRELYR-- +>[subseq from] Uncharacterized protein n=1 Tax=Lentibacillus amyloliquefaciens TaxID=1472767 RepID=A0A0U4ED90_9BACI +-kQLEADVRSIISGFHSPVGITIKN--ETETL-NINANSRMPAASVIKIPIIMEAFRQAE +NGGLDLSETLSVPADTIVGGSGVLQALSEDVMTVLDVLTLMIIVSDNTASNLALKWV-GI +DHVNRLCRELQCHHTEIQRYFMDMKAA-EEGLENTTTAGDMVNFLEEIASPWLLSRNSAK +RILHIMTRQQLSSKLPAYHTNDDIIMANKTGELAD-AEHDVGIFQFQERT-VFAAVLMDR +VS-DHVAARQAIARIGKMIMD-- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Omnitrophica bacterium TaxID=2035772 RepID=A0A419DWM9_9BACT +-qELGRHLKSEIDQFKGEAGIVIKDLHAGWEL-SYQKSKLFPSASLAKIPIMAGCFLAAE +QNLIKLNRDISLKSTDKLTGSGMLKDLPAGKFSVDRLIGFMIYDSDNTATNILTDLL-GI +DYLNKTFQDFGLQNTFLSRKIADYRSR-DKGLENYTTAEDMVLLLEKIYRRALGNKSVSD +RCLRILKLARM-NDRIPKYLPPEITVAHKTGLEK-GVCHDTGIVFTCSGD-FIIVVLTKH +ADANSAPSKEFIARISLQAYKYf +>[subseq from] Beta-lactamase n=2 Tax=Bacteroidales TaxID=171549 RepID=A0A3S9W079_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase class A n=2 Tax=Halomonas pantelleriensis TaxID=48727 RepID=A0A1G9M525_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +--VAAFAERLGLAELALDGYDAAF-DAYEAGRLNTGTLAAFGDLLATLVRGGGLSDASRE +ALLTIMQRTSSGEARLKAGFGDDVRFAHKTGTQHR-RTCDAGIAHRGEAREVAVVACTRG +PI-DVVPHERLLAEVGAAI---- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Leptolyngbya sp. TaxID=47254 RepID=A0A2W7A8I8_9CYAN +----RGELEQLSTLTPGTPVAFAIDLDSGQYV-DLGGAEPVAAASTIKVPILIAFLQQVD +AGTMALNQSLVLQEDSMAGGSGTLREAVGTEYTALDIATRMIVVSDNTATNMMIAALGGI +EALNQTFVTWGLEHTVLRNPLPDIEGT------NTTSAKDLALIMALIDQGGLLMPRSRD +RLFSIMQRTQN-DSLIPSGIRDQSLTANKTGDIG-GMLGDVALVDVPNGKRYGLAVLVQR +PSND-GRASELIRRMTETI---- +>[subseq from] serine hydrolase n=1 Tax=Proteocatella sphenisci TaxID=181070 RepID=UPI0004B7A781 +------SITQKLKALPGKTGFFYKNLETGETI-AWNENEKFIPASVIKLPVLMAIFNLAE +SRAADLTEYIKIKQEEKMPSCGALNSFTGEPVDIRTLCNLMITISDNTATNVLISHF-GT +EKLNEVFTDMGLADTRVNRKLFDMEAS-KKGIQNSATPKEMAYLLEELHFNRFINEKVSE +DIKEILHRQQI-NHKIKEMLPPGTRAAHKTGEDDY-ISNDVGIIYAK--QPFIFSFFSND +TKVSD------------------ +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A2N8S1C6_PSEST +-----ARLAHVDRQTPGQLGVYVKDMETGISV-SYHGEEPWYLASTVKVPVAIAVMRQTE +QGELTLDSPVALLASDYVDGAGPTNSHAPGKLSVRFLMDQMLIHSDNTASDMLIRLV-GI +EQVNAIAQELAPEGLGPITSLADVRRRYYATPFNSGTLKAYGDLLSALDAGIALKPESTE +YLLSVMRRVQTGKQRIKAGLPPGTGFAHKTGTQR-ARICDAGLVDQPGSTRLIIVACVRG +V-ASASQAERALRGTGEAVT--- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella pectinovora TaxID=1602169 RepID=A0A0D0I3H3_9BACT +---LTDSISQIVSACPGEIGVAVI-VYNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00132FB8AA +----------------------------------------FAMCSTSKVMAAAAVLKKSE +SEPNLLKQRVEIKKSDRVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKA------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Xenophilus sp. E41 TaxID=2282216 RepID=UPI000EF56402 +-eALGAQIDRIDRATPGELGVYVKRLNGGETH-RHGAERFWYLGSMTKVPIAIAVLQQVD +AGKLKLSDSVELQDADRIDVSRVVRERTGRRYTVDALLDRMLKDSDNTAANMLIRTV-GE +DTVQRSAQALGTQGFK-------------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Xenophilus sp. E41 TaxID=2282216 RepID=UPI000EF56402 +------------------------------------------------------------ +----------------------------------------------NTALVQVANAPLGP +GRVQAVQRALKLKTGDLQRTIDDAYDRYYRHDINSATLDAYGAMLEKLARGELLQPASLQ +RLYAAMKLGTFTNHRLQAGLPRSEPFIHKTGTQYR-RACHAGVLRPQDRADAVVVAVCAA +GMDEHKDVDAIFQQVGRAVAQ-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9LBQ4_9BACT +haRLAAEMDRVAERLNGVLGYAIKDLSTGEVF-YRNADLVFPTASSIKLTVLLELMRQAQ +EGELSLDEKHTVRRSETPATEPILHFLGDGTMTLRDLATFMVVLSDNSATNILIDRA-GM +DNVNAEIARLGLKETRLRRHMIDIDAA-RRGNENVSTPRELMILLEKVRAGGVLDSAHTK +EYFDLLALPK--DSLFNKALPSTVRIEDKPGALD-AVRCDAGIVDVPGHA-LAMSLMTTY +LAG-NDEGERAVGEIARLAYAHf +>[subseq from] serine hydrolase n=1 Tax=Blastopirellula cremea TaxID=1031537 RepID=UPI0011C01A21 +----SALLLPLIEKHRGDVGVVIQHFPSGESF-AYQADKPMSTASLIKLPLLMATYAKVH +DGGVSLDTMITLTEADKVPGSGILTKHFSPGLSLRDAIQLMVAYSDNTATNLVIDTV-GL +DTTNTLMKKLGCDETRLNSKVFRRDTRSKAFGLGSTSANDMQRMLRALHDRSFVDQATSE +QILKHLYDCED-RMKAARYLPANVKVAHKGGSVN-AARTDAGIIDLPDGGAILFCVLTMN +NQTDDNEGDVLSAKIGKAVYDYf +>[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3M4L5_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +QRVQALARALDDADTFQVRTMDEAYDRYYRHRFNTATLTGYGAMLENLVRGKLVTPAHQQ +ALFKDLKFDTYDAYRLEAGLPRSVRFIHKTGTQLH-RACHMGVIAPQDGQSAIVVATCAE +GLDEQKEAGKAFEAVGRAITQ-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides TaxID=816 RepID=BLAC_BACVU +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNKSQASQYVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. PA15(2017) TaxID=1932111 RepID=A0A1Q9Y4Z0_9PSED +---LLERLQATAARQDGELGVYVKDLHSNLAV-TLQAERLWYMASGIKVPVAIAVLRGVE +RGDWQLDTRLPLAANDFVDGAGSTNQYGPGELSVRFLLEQMIIYSDNTATDRLIRLV-GL +DAVNGLVRELVPEGFEPITTLGDVRRAYYSSNLNAATLSAYGELLERLAEGQALGQAQTA +YLLEVMGRVKTGSKRIIAGLPKNTHFAHKTGTQR-ARICDSGLIRTPERAEAVLVVACVE +GELSLAKAERTLRQVGEAL---- +>[subseq from] Beta-lactamase n=3 Tax=Bacteroidales TaxID=171549 RepID=A0A3N2KX94_9BACT +---MADSITKIVDDYPGEIGVAVI-INNTDTI-TVNNENIYPMMSVFKTHQALAVCDDLD +NKGISLDSLMTIQRDELDAWSPMLKEHHENVLPVRDLLRYALSQSDNNASNLMFKKLVDV +AATDCFIATIPRSSFKIAYTEEEMSADHDKAYANSTSPLGAAILMNRLFTDSLVSHEKQS +FITATLKECVTGVDRISAPLKAGVTIGHKTGSGYTNAHNDVAYISLPDNTCYSLAVFVKD +FKGNESEAAKAIARISATVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. 2017 TaxID=2169540 RepID=A0A2S1H398_9BACI +-----EIIQQFIENSSYKIHTVVQDYETDEVLvHIRADEVFSSASVIKVPILIAILHHLQ +QKGGDLQQVLTIASENVVEFSVITEQQ-QTSATLYELLTWMIITSDNTATNECIDFL-GM +DEFNRYFKEIGLSNTVVQRKMMDFERQ-QLGLDNETSARDMQHLFKLIYEGKLLEPKWND +IAIDILCRQRS-QDSLKRYLLEPVKMAHKTGGLDT-VDHDVGIVYTDGT-AYFIGVFITE +VTNN-EKAKQEIGLISKMVYEH- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7VMA3_9BACT +-dKLRSRIETVDRGLDGVLGLSVKDLKGGMTL-EIRPQEPFPQASSIKLAVLYELFRQAE +EGRVDLRE-LTRPPLPRVRGGGVLQELGDRLLTWRDLAVLMMGWSDNAATNVLIDRV-GM +EAVNRRLDSLGLRATRLRRKMMDLEAARRG-DENVSTPAEMRQLAEAMYAGAGLSKERVK +DLLAVMAVPKD--SPFRVPLPEDLVVADKPGTLE-AVRCVTAIVDLPGR-PYAVSIMTTY +LRHD-ADGEAAIKQISSALYETf +>[subseq from] Uncharacterized protein n=1 Tax=Salinibacter sp. 10B TaxID=1923971 RepID=A0A2P6C2C1_9BACT +-----QHIRPLLESIDGECAVAVRSLESSEEV-LLDANVEFHAASTMKVPVMVELYRQAA +NGQFSLDDSIRVENESIVDESPYAYEHLGDRRSIRTLMRVMITASSNLATNLLLEVV-GP +EKVTRTMHRLGAEGLQVRRGVEDSK-AFRRNRNNTTTAHGLLVLFEHIARGTAVSEEASA +EMINILKAQEH-TEMIPARLPDTVEVAHKTGWIT-GVRHDAGIVFVPEGPTYVLVLLSRN +LS-DVPAGVETLSRISRVVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7S127_9BACT +--ALRQRIDAAARKSDARIAVALHDAESGAEL-HYDADRWFHGASTIKIAILLAVYGEID +RGRLAPQSRLHVRNRFLSAGSPFRHASIGKTMRVSELALHMIAMSSNLATNLLLDLI-GL +ETVQRTIERFGLTGLDIRRGVEDE-KAFEHDIVNRVTANGLVGLLRLIAEERAYSPELSR +EMLDILHQQEF-KKGIPARLPRDVRVAHKTGDISS-VAHDAGVVYAPGRKPYVVAILTEW +AA-DAGSRSPTIASISHAVYDY- +>[subseq from] serine hydrolase n=1 Tax=Acidovorax valerianellae TaxID=187868 RepID=UPI001113FE94 +------------------------------------------------------------ +----------------------------------------------------------GP +KRLQALARSLDVAAGALNKTLDEAYDRYYRHQANTATLEGYGAMLEKLVRGQLVSPAHQQ +LLYKDLKFDTYDAYRLEAGLPRSVRFIHKTGTQFH-RACHMGVIDPQNGRRAIVVAACAE +GLDEMKEAGKAFEQIGRAITQ-- +>[subseq from] Serine hydrolase n=1 Tax=Muribaculaceae bacterium Isolate-105 (HZI) TaxID=2486472 RepID=A0A3N2MN95_9BACT +---MTSLLKDFAAGKDARIGIAVI-INGRDTV-SVNGHRDFPMLSVYKFPQAIAVADYCV +RHGISSADTVAVGHEEILAWSPMRDRYGIRDLPLSELLAYSLQQSDNNACDILFRLIGGP +QAADSLMNTLGFDDIVMASTEEEMHGDTYLCYQNRSTPLAMARLFDRLYRQGMRSESALE +TIATMMIQCATGLNRLPAPMATNAMIGHKTGTGDRNGINDAGYVFLPDGNGYSIAVFIAD +SAYDMAATEQLIAEISTIVFN-- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A537KJX7_9BACT +------------SSQKGIFAVAFKEVATGKDL-LINEKEVFHAASTMKTPVMIEVFRQAA +RKKFSLNDSITLKNESIVDSSSYSYKHIGEKRSIHDLVYQMIIASSNFATNLIIEKV-GA +KNVTETMRHYGAKDIQVLRGVEDQK-AYDKGLNNTTTAYDLMLIFEKISKGKAVNRKASK +AMIDILLDQKF-NTIIPAQLPKDVKVAHKTGFIT-GIHHDSGIVFLPDGRKYVLVLLSKN +VE-DEAATIKAMANVSGMIYQ-- +>[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T051_9BACT +-tALQNELTDFVKDKDARIGMAVI-IDGKDTV-AVNGKEDFPMLSVYKLPIALALADNYR +VKGLDFSEPIAIAKEDLHLYSPMTGRLLASSMPTREILNYMLQQSDNNASYLAVKKLGGT +ENVMKWLSKSGLSGVKVVSTENEMHINPELSYKNSSTPIAMARLLDKLDTE--WNDSLSK +EIKQMMETCKTGENRLAKLLPTNAVTGHKTGTGFIMAVNDVGYVHLSNGHRYSIAVFIAD +AHYDMAESENIIAQISEMVWR-- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=E4PXX3_STAAU +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKK--- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Niastella caeni TaxID=2569763 RepID=A0A4S8I3N1_9BACT +-nKLQDQISSRLAEQPGDFAVAFKDLTTGDTL-LINDQAFFHAASTMKTPVMIEVYKQAA +AGTFTLNDSFVLKNESIVDSSVFSYRHLGEKRTLYNLVYDMIIKSSNLATNMVIELV-NA +RNVTQTMRQLGAKRIQVLRGVEDSK-AYEKGFNNVTTAHDLMVIFEKMAKGEIVDSASSQ +AMINILLNQQF-KEIIPARLPRDVKVAHKTGNISH-VQHDSGIVFLPNGRKYVLVLLSKN +LQK-EEQAIKAMADVSEMIYNY- +>[subseq from] serine hydrolase n=1 Tax=Aquincola tertiaricarbonis TaxID=391953 RepID=UPI0012ECFFFA +------------------------------------------------------------ +----------------------------------------------------------GP +QRVTALRRTLGVQASELQPTLEEAYERYYRRGLNSATLEAYGGMLEKFVKGELVSPQHQQ +VLFIDMKFDRYDNYRLEAGLPRTVKFIHKTGTQFQ-RACHMGVIHPQDGRNAIVVATCAE +GLDENKLAGQMFEQIGRAITQ-- +>[subseq from] Beta-lactamase n=4 Tax=Bacteroidales TaxID=171549 RepID=E5WU37_9BACE +----TDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium oral taxon 876 str. F0540 TaxID=1321778 RepID=U2ERJ0_9FIRM +-----KEIKRYIDTRIGDYSFYFEDIDSGYSY-SLNEKAIMPSASCIKVPIAMALLKEVE +NGSINLDHKVFVNKEEMVEGSGIIHELDEKDYSIRELLAAMLIQSDNTATNKIIDSL-GM +DKINNYIKQMGLKDTLLKRKMMDLKAR-ERGLENITSSLDLANCFKELHNGNYLSKNSRE +YIVTILRKSQN-RDKLPFYMPREWKIANKTGSLS-GIENDAALINIDKGN-FVFVVMAKS +LPN-NIYGIVTISRVGKMMWD-- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Leptolyngbya antarctica TaxID=268115 RepID=A0A2W4VVN8_9CYAN +----RGELEQLSTLTPGTPVAFAIDLDSGQYV-DLGGAEPVAAASTIKVPILIAFLQQVD +AGTMALNQSLVLQEDSMAGGSGTLREAVGTEYTALDIATRMIVVSDNTATNMMIAALGGV +EALNQTFVTWGLEHTVLRNPLPDIEGT------NTTSAKDLALIMALIDQGGLLMPRSRD +RLFSIMQRTQN-DSLIPSGIRDQSLTANKTGDIG-GMLGDVALVDVPNGKRYGLAVLVQR +PSND-GRASELIRRMTETI---- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A120GMN1_9BACI +---IENDIWALVDAFDGNIAYKIES-GFGDMI-GYQEEDSFQSASLIKIPMIIEGYRQSE +RKNIYLNQPVTIPPNAVTGGSGVLHALSNKVLTVEDLLTLMITVSDNTATNMMMSLL-GI +DEINRCIQELGLKNTILGRKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE +RILRVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVSHDCAIIRSETQT-VYAAVLTEN +M-KSEEESRQVISKIGKLIYDH- +>[subseq from] Serine hydrolase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520H8U6_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +QRVEAVRRALNLKTADLQRTMDEAYERYYARKLNSATLDGYGALLEKLVRGQLLSPAGTR +RMFEDMKLGIFTNYRLQAGLPRDVPFIHKTGTQHR-TACHAGVIDPEDGADAIVAVTCAA +DVDEQHEAGRIFERVGEAIT--- +>[subseq from] serine hydrolase n=1 Tax=Rufibacter sp. DG31D TaxID=1379910 RepID=UPI000664784A +-qKTEQELRGILEKSSALTGLVAIDLTSGEAF-RFNQDLVFPQASAIKVPILLEVYKQAQ +AGKFALTDVRRIAPGQVVGGTGIIKDLEDSTFSIRNLAVLMIALSDNTATNALLDLV-GL +SNINASLQAMGLKQTRVQRKMIQAAAS-GRGEENISTPAEAAKILQMLYKGEFLNKATSE +EIISILKKTNRETSRLAPGLPDHVPLAFKPGILN-GVSTEWALVLLPER-PYAVAIMENF +K--PMGQDGMVLEDVSKVLYQYf +>[subseq from] serine hydrolase n=1 Tax=Thermobaculum terrenum TaxID=166501 RepID=UPI0009FF52AC +---LQERIANIIDSV-GYFGVAAKDLTQGREL-FINADETFNTASVIKVPIMIELFRRVY +EDNVSLDDRLILEDRFRTGGSGILKEFRSGLLTLWDLCVAMIALSDNVATNMLIDYL-GI +DAINRCMDSLGAHNTRLHRMV-GFKSIKPDQPKGRTTPRDMMMIFQKLAEGNVISESASE +EMIAILAKQHD-RNMIPRLLPDSAIVANKTGAVD-GVRNDVALIRFADGRQWVICILTKD +LRKVDHEGEIAIAKIALEIYKEw +>[subseq from] Beta-lactamase n=1 Tax=Prevotella buccae TaxID=28126 RepID=Q8KT59_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFVATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Emticicia sp. TH156 TaxID=2067454 RepID=A0A2N4X7H9_9BACT +------KLNDYLRQLPATIKVSMVSVTGHRYF-AYRPEAIVPAASVIKIPVLIELMDQAG +KQKIELTKIYKLTAADKTGGSGIIAGMPDGKFTLRELAQEMIHSSDNTATNVLIREV-GM +KAINDNLIRLGSTHTRLNRIMMDTLAA-RQGRENYVNAVEINDLLRKIYNNNIATPALCK +EMLEILKNCAD-TTTIPRYLPRQVAIAHKTGELSY-VRGDAGIVYT--GNPFILSVFVEG +FD-EMSQAEKIIGDLALICWE-- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7JK35_9BACT +--AVRHQIEKIEKESGAKIAVALHDSETGFEI-HYHADRWFHAASTIKVPILLGVFAAID +RGELLPHSRVHVRNRFLSVDIPFRHNAIGKMMRVDELAYHMITTSSNLATNLLLGVI-GP +ASVNETLRELHDDGIELKRGVEDEL-AFEKGINNMVTANGLLRILVMLADGKAFSPALSR +RMMDILHGQEF-NQGIPARLPKGARVAHKTGEIST-VAHDAGVVYLPKRKPYSLVILTEW +DP-SATARSRTIAAISQTIYE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chryseolinea serpens TaxID=947013 RepID=A0A1M5TZ58_9BACT +hdKVKETITQALAGQQGTFAVAFKDLSTGEEL-FINEHMPFHAASTMKTPVMIEVFKQAA +EGKFSLTDSILIKNESIVDGSPYHYRQVGKKRTLQSLVYEMITVSSNLATNIVIEWV-DA +KKVTQTMHDLGAKDIQVLRGVEDDK-AFEQKLNNSVTAYDLMLIFEKLAKGEAVNPEASK +AMIAILLDQKY-NDIIPAKLPRDVKVAHKTGWIK-GLHHDSALVMLPDGRQYVLVLLSKD +LK-DEKAAVEALNDVSKTLYDY- +>[subseq from] Serine hydrolase n=2 Tax=Terrimonas sp. NS-102 TaxID=2171976 RepID=A0A2T7Q797_9BACT +--ALREKISNIFSQFEATFGVAFKNLNTSATF-FWNAEDIFHSASTMKTPVMIEVYKQAA +QGKFSVTDSMLVKNSSIVDGSTYSYLHIGKKLPIRDIVFRMITVSSNLATNNIIELV-GA +KNVTATMRKLGTKNMQVLRGVEDKK-AFEKGLNNITTAYDLVLVMESIAKGTVADKRSTD +DMLDILLHQRF-KRVIGGKLPADVKVANKTGAFK-GVRHDSGIVFLPDGRKYVIVLLSRG +IE-DDEKSAAALAEVSRLVYEE- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella oralis TaxID=28134 RepID=Q8KT51_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KANNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLVTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] serine hydrolase n=1 Tax=Spirosoma rigui TaxID=564064 RepID=UPI0009AF998B +---------------GVRVNLAVQSLADSSESfVQGATDQVPSASVIKLPIMIEAMEQVK +AGRLDLDEIHILTDGEKVGGDGVLKTYSHRSVAYRDLLRLMMIYSDNTATNIFINEL-GM +DAINRRIQALGLSGSQLNRVMMDTLAV-RQGRENYVTARDMNRLLGKLYRNEVATPELCA +HMIAILKQNED-MATIPKRLPAGTVVAHKTGTLAY-IRGDAAIVYA--REPFLLSIFVAG +VP--TPQAEQLIADISLICYTHf +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. WP24 TaxID=2604469 RepID=A0A5D0TP62_9ACTN +-----GQLQQVVDASTANAGVAVRDLSGDQQI-ALNGAFRPKAASVIKLWILVELLRRVD +CGQVSLDDGVLVTPSQVVDGTGELQHETFPQVTLYRLAEYMIKYSDNTAANVLIDYFGGF +APVNDLIDSMNQRETILARKMLDTEAA-MRGEENYTSPDDVVALLGAVWEAQILTPATRD +LMIGFMAEQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSQ-VAVAFLTSG +PM---AGGDETVRRLARTVYDY- +>[subseq from] Beta-lactamase n=5 Tax=Bacteroides TaxID=816 RepID=C6Z584_9BACE +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase class A n=2 Tax=Micromonospora pisi TaxID=589240 RepID=A0A495JQ71_9ACTN +---LTERLRAIVAASPNPTGVAVRDLSGDQQI-GVNGTFRPKAASVIKLWILTELLREVD +CGWQRLDDGVLVEPKDVVGGSGQLQYETFPQVTLYRLARYMIIYSDNTAANVLINHLNGF +VRVNALIDTMLLKQTALNRRMLDTAAA-ARGEENYLTADDVVSLLGAVWDGNLLSPVSRT +LMISFMLEQTI-NTKIPAALPPGVPVAHKTGELPD-ASHDVGYLLIPHSE-VAVAFVTSG +PE---ATGAETVRQLARAVYDY- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=unclassified Prevotellaceae TaxID=224765 RepID=UPI00094E1C15 +---LTDSISQIVSACPGEIGVAVI-FNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase class A n=1 Tax=Pontibacter chinhatensis TaxID=1436961 RepID=A0A1I2RFE8_9BACT +-qQTENQLAAIINRSPAVTGLVAVDLTTGDTF-SFNAGVVFPQASAIKIPVLMSVYKQAH +EGKFSLTDIRQVAAADVVGGTGVLKDLDGPPMSIRNLGILMITLSDNTATNALIDLV-SM +QETNAMLRALGAKHTLLQRRMINAAAS-GRGEENISTPADAAKILQLLYKGEFINKAASE +EIVSILSKTDRQTSRLAPGLPDNVPIAFKPGILN-GVSTEWAIVLLPER-PYAVAVMESY +KV--KGQAEHTIEDLSEVLYQYf +>[subseq from] serine hydrolase n=1 Tax=Gemmatirosa kalamazoonesis TaxID=861299 RepID=UPI0004B6B941 +---LRQKIEAIEARSPKALAVAMRDLGTGLTF-DHHADRWFHAASTIKVGILLGVYGAIH +EGRLVAQSRVHVRNRFSSAGSPFRHQHIGSTMRVSELALHMIATSSNLATNLLLDLV-GL +DTVQRCLESLHIHGVDVRRGVED-ERAFEHHVNNRVTADGLAALLRAIAEERAFSPEISR +QMVDVLHAQEF-KSGIPARLPKAVRVAHKTGEIST-VAHDAGIVYPPDCPPYVLVVLTEW +EP-DGTGRSATIAEVSRAIYE-- +>[subseq from] serine hydrolase n=1 Tax=Larkinella terrae TaxID=2025311 RepID=UPI0012AD9868 +-eQLKQQIELEFKKQPGRFAVAFKDLTNGREL-LIREQEVFHAASTMKTPVMVEVYKQVA +QKRFSLTDSVLIKNQSIADGSLYSYTEVGKKRTLYSLMYDMIIVSSNLATNLIIDLV-DA +TKVTQTMRELGAKNSNVLRGVEDTK-AFQKGLNNTVTAYDLMVLFEKIATGKAVSSQASE +AMIKVLLDQHF-SSVIPAKLPNDVKVAHKSGSFAT-VRHDSGIVYLPDGRKYVIVLLSKE +MP-DDAAATETLATVSGLIYQY- +>[subseq from] Serine hydrolase n=1 Tax=Salegentibacter mishustinae TaxID=270918 RepID=A0A0Q9ZAZ2_9FLAO +-kELQNKIASIFEENQGEFAIAFKNISEEKDSiLINAHENFHAASTMKTPVMIEVFKQAS +EGKFSLQDSLVIKNESILDGSSYSYEQIGQKRSIEDLVTDMIIYSSNLATNIIIELV-DA +KNVNQTMREMGAMDINVLRGVEDMK-AYEAGLSNSTTAYDLMLIFEALAKGKAVNAEADK +EMLHILQQQKH-TDLIPALLPENLKIANKTGWIT-GVHHDSALIELPDGKKYVLVLLSKN +MK-DMEAGTKMLSEVSKLIYDH- +>[subseq from] Serine hydrolase n=1 Tax=Luteimonas sp. XBU10 TaxID=1132694 RepID=A0A5D4XUQ7_9GAMM +-qELQRRLAAADARYPGDLGVYVRHLERDESF-SYLAEEPWYLASGIKVPVAIAVLRAVA +RGELALDARITLREDDFVDGAGATNSVRAGSLRVSWLLEQMIVHSDNTASDVLIRSV-GI +DAVNAVAAELTDTAGVRITTLADVRRAYYATHVNSASLVDFGRMLAALAEGHALPARETA +YLLDLMARVQTGKRRIRAGLPPGTRFEHKTGTQHR-RSCDLGIATVPGSARVVIAACARG +TG--TAAAERALRDVGAAVT--- +>[subseq from] Beta-lactamase n=4 Tax=Bacteroidales TaxID=171549 RepID=Q5UAF8_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGCNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Prevotella melaninogenica TaxID=28132 RepID=Q5XLF9_9BACT +---LTVSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase class A n=2 Tax=Pyrinomonas methylaliphatogenes TaxID=454194 RepID=A0A0B6X2N0_9BACT +-kALDQRVRAEISKFKGHVSLFAKNLDTGASY-GFGADDRVRTASTIKVPIMVEVFARVA +EGKAKWDDELVLTEAKKVSGSGILLELSDGLLTLRDAVRLMIILSDNTATNLILDQI-TT +DAVNDRMDQLGLKQTRVLRKVGGGGEMIPENKRGVSTPREMVALLEKLERGEVVNTEASR +EMLAIMKRQQY-RDGIPRALR-GVEVANKTGALDR-LRSDVGIVYTPRGR-IAMAITCDD +M---------------------- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella melaninogenica TaxID=28132 RepID=Q8KT52_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTFKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] serine hydrolase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=UPI0011A6F74D +------------------------------------------------------------ +-----------------------------------------------------------P +QRAEAVRRALALPAGALRSTIDEAYADYYAEGRNSATLVGYGAMLERLVRGDLLSPASTE +RLFQAMKFGTRGSYRLEAGLPEHLRLIHKTGTQHQ-RACHMGVVQPQDGDATVIAVCAAE +LD-EQRAAGRLFEAVGRAIA--- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. ICM33 TaxID=1161412 RepID=X6Q3X8_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5Y7E9_9BACT +---LNEELERLNDQSKARIAVAVHDLESGWRF-SLRADRWFHAASTIKVALLLAVFRAAD +ESRLRLDDSLHVRNRFFSAGSPFHYQAIGRTAKISALAEGMISSSSNLATNLLLDLV-GV +EYARKVLRDAQVDGVELRRGVED-HAAHQREINNEVTADGLVRLLSAV-RGDFLSKESKE +QAIRILLDQRF-KSMIPAGLPAHATVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +AS-EQDGRRETVAAISEAIYR-- +>[subseq from] Beta-lactamase (Penicillinase)-like protein n=1 Tax=Ramlibacter tataouinensis (strain ATCC BAA-407 / DSM 14655 / LMG 21543 / TTB310) TaxID=365046 RepID=F5XZA2_RAMTT +--RLPAELAAVDARHRGQIGVHVRDLQTGVRV-NHHADQDWYIASMVKVPVAIAVLRGVE +AGLFTLDTPLRLRAADYVDGAGATNGHPVATLPIRFLMEQMIIHSDNTASDMLIELV-GL +PQVNALVRSLVPQGFGRITTLAEVRRAYYAGGLNSARLDAYGQLLALLAQGGALGPDATA +YLLGLMERVATGPNRIRAGLPADARFAHKTGTQRQ-RVCDAGLVRMPGAGAGAVVVACVR +GEASLARSEAALRDVGEALC--- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora musae TaxID=1894970 RepID=A0A3A9XRX0_9ACTN +-----GQLQQVVDASTANAGVAVRDLSGDQQI-AVNGAFRPKAASVIKLWILVELLRRVD +CGQVSLEDGVLVTPSQVVNGTGELQHETFPQVTLHRLAEYMIKYSDNTAANVLIDYFGGF +APVNDLIDSMNQRETILARKMLDTEAA-MRGEENYTSPDDVVALLGAVWDAQILTPATRD +LMIGFMAEQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSQ-VAVAFLTSG +PM---AGGDETVRRLARTVYDY- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella pectinovora TaxID=1602169 RepID=UPI0005B7274F +---LTDSISQIVSACPGEIGVAVI-FYNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013B36BB1 +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAALLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDRTEPT------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. M6-12 TaxID=2054166 RepID=A0A2N5I2K8_9BACI +---LEKAVKIEIEKCSGRVGLYLEL--DGGTI-EHNSNEVFRSASLIKVPILVEGFRQKE +EGRIHLNQPVTIQRRDKVGGSGVLQVLSDKSMTLKDIMTLMIIVSDNTATNVMIDLL-GM +DSINRTIKELGLEKTILERKMMDFQAA-EQGKDNLTCAADMALCLKAIQEASFLSDESSR +EMADILKNQQF-LDKLPAMMDDKVAVAGKTGGLHC-IEHDCAIIRYGEK--VAYAAVLSD +ELPSKEDGRRTISAIGKLIFD-- +>[subseq from] Serine hydrolase n=1 Tax=Flavobacteriaceae bacterium TaxID=1871037 RepID=A0A2E1RIV5_9FLAO +-dSLEERIVGLLDSEKGEFAVAYKNLSTGETI-LINENEEFHAASTMKTPVMIEAFKKNN +EGLISLDDSILIKNESIVDGSIFKYEKIGSYLTLKELIYDMITISSNFATNLVIDYI-GT +KEINNTMRSLGANNINVLRGVEDIKA-FNNGMNNTTTAHDLLKIYENLAKGNIISSDISD +EMINILKNQKY-DDIIPKYLPKSVEVAHKDGWIS-GVRHDSGIIFLENNKKYVLVLLSKK +LEN-EIEGADILAKISLEIYN-- +>[subseq from] serine hydrolase n=1 Tax=Rhodothermaceae bacterium RA TaxID=1779382 RepID=UPI0012D35464 +-----------------------RDPHTNTRY-DFHAERLFHAASTMKVPVMIEVYRQAE +AGRFSLDDSLLVRNTSIVDGSTYRYRMLGRRMAIRDLVHRMITVSSNLATNLLIDLV-TA +DSVQATAERLGVRHMQVRRGVEDLLA-FRQGLNNTATAADLAVLFDALRRGAAVSPEADR +AMIDVLLDQQF-GDLIPAGLPPGVRVAHKTGAITR-IHHDAAIVYPERGPAYVLVVLTEG +ID-DRARSAELVAEVARAVHQ-- +>[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3Q3K9_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +RRVQALARALDVPQKSLQQTMEDAYARFYRRGDNTASLVAYGGLLENLVRGKLLNAEHQQ +LLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQFQ-RACHMGVIDPQDGQRAIIVATCAE +GLDEQKQAGRAFESLGRAITQ-- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella oralis TaxID=28134 RepID=Q8KT50_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSRFQIAYTEEEMRADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase regulatory protein BlaB n=2 Tax=Nocardia otitidiscaviarum TaxID=1823 RepID=A0A379JJ68_9NOCA +---AETRIRAVFADAGCTGWLHARRCDSGTEI-SLGGDERVVVASVYKLPLFVAFCRHID +AGRVDPTARITVTPSDCTPPTGIAALRDPVTMSLRDLAASMMTVSDNAAADVLLGAI-GL +AAVEELLDDLGLTRTRIIGGTADLHRAYDPSYTSATTPEEMTRFLHALWRGDILSPERTD +YARAVMRAQVW-QHRIAAGFPRSVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLPAVDAAIAEVARIAVT-- +>[subseq from] Beta-lactamase n=1 Tax=Gemmatirosa kalamazoonesis TaxID=861299 RepID=W0RL99_9BACT +---LRQKIEAIEARSPKALAVAMRDLGTGLTF-DHHADRWFHAASTIKVGILLGVYGAIH +EGRLVAQSRVHVRNRFSSAGSPFRHQHIGSTMRVSELALHMIATSSNLATNLLLDLV-GL +DTVQRCLESLHIHGVDVRRGVED-ERAFEHHVNNRVTADGLAALLRAIAEERAFSPEISR +QMVDVLHAQEF-KSGIPARLPKAVRVAHKTGEIST-VAHDAGIVYPPDCPPYVLVVLTEW +EP-DGTGRSATIAEVSRAIYE-- +>[subseq from] serine hydrolase n=1 Tax=Ramlibacter tataouinensis TaxID=94132 RepID=UPI0009D9B371 +--RLPAELAAVDARHRGQIGVHVRDLQTGVRV-NHHADQDWYIASMVKVPVAIAVLRGVE +AGLFTLDTPLRLRAADYVDGAGATNGHPVATLPIRFLMEQMIIHSDNTASDMLIELV-GL +PQVNALVRSLVPQGFGRITTLAEVRRAYYAGGLNSARLDAYGQLLALLAQGGALGPDATA +YLLGLMERVATGPNRIRAGLPADARFAHKTGTQRQ-RVCDAGLVRMPGAGAGAVVVACVR +GEASLARSEAALRDVGEALC--- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5PG77_9BACT +---LNEELERLNDQSKARIAVAVHDLESGWRF-SLRADRWFHAASTIKVALLLAVFRAAD +ESRLRLDDSLHVRNRFFSAGSPFHYESIGRTAKISALAEGMISSSSNLATNLLLDLV-GV +EYARKVLRDAQVDGVELRRGVED-HAAHEREINNEVTADGLVRLLSAV-RGDFLSKESKE +QAIRILLEQRF-KSMIPAGLPAHATVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +AS-EQDGRRETVAAISEAIYR-- +>[subseq from] Beta-lactamase n=2 Tax=Terrabacteria group TaxID=1783272 RepID=R7LIT6_9CLOT +-----SSLRNLSAMYSIHPSIYVWDYETGNYA-DVNANEIFPTASIIKLPVLVQLFRSIE +KNQLTIYDEMPLTEYYRTEGSGSLQFKAANSYTIDTLARMMITESDNSATNMIMARLGSM +TDINQGIREWGLKHTYVQTWLPDLGGT------NHSTARDMATILYNIDNPKFLSTSSRE +KIFDYMGHVHN-NRLIAAGLPAGAEFLHKTGDIGK-MLGDAGIVYAPNGKKYIVVIFANR +PHN-SPLGKEFIVKASEIIYN-- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus thermocopriae TaxID=1215031 RepID=A0A6B3TMH9_9BACI +---WKEKITKELVDFKGRVGVAIEI--ENERY-EFHSEEVFPSASVIKVPILMECLKQSE +HGNIDVDEFIKITE--RTGGSGVIQALSTNLLTIKDLMTLMITVSDNTATNMLIDFV-GM +DPINRTMEELELHTTRLQRKMMDFAAK-EKGLDNVTSPSDMVKCLKIIHEGDFLSANSRR +MALDILHFQQFHDKLLAMIDTDKVFTANKTGSLPN-VENDCAILKVGSKT-AYVAILTDK +LS-DPYEARQVISRIGKHIYH-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sulfobacillus thermosulfidooxidans (strain DSM 9293 / VKM B-1269 / AT-1) TaxID=929705 RepID=A0A1W1WGQ0_SULTA +------ELQNLIQTLPGRYAVFAKNLETQKTF-AYHEHDIFPSASVIKVPILIELYRRVE +EDHLSLDHLLLMRKEDQVGGSGVLKDLTPGTYSLRDLATLMITVSDNTATNLLIDYL-GV +DWVNSTIRRLGTQNTELIRKLQRVPAE--YDQINHTCAYDMALLMEKLARGTAISLAVSE +QMVNLLTRCQVSIAKIPADSVKEVIIAHKTGSLSE-ASHDVGIVYSPHMN-YVAAILSEG +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A661XVV8_9BACT +--QLSKDLSEIITDSQGTYAVAFADLKTGDTL-FINGHESFHAASTMKVPVMIELYKQAQ +EAKFSLDDSILVKTESIVDGSLYTYEKVDSMLPIRELMYHMITKSSNLATNILIELV-DA +KKVTATMRDLGAPDIEVLRGVEDLKA-FDSGLSNSTTAYDLMKILEAIGMEKIINEEACG +EMMNVMFDQQF-NKIIPSQLPSEVKVAHKTGSIT-GVQHDAGIIVLPTGHKYVLVLLSKE +LE-DKDKGVETLSLISKKVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Cyclobacterium halophilum TaxID=1416801 RepID=A0A1H7BK67_9BACT +--ALEEEIRSLMQATEGDFGLAFRMLDTDREL-LINESEVFHAASTMKTPVMIELYKQAA +AGEFDLQDSIRIVNESIVDGSSFRYERIGEKATIYELMYQMIIKSSNLATNILIDRV-DA +KNVTQTMRDLGAEDIQVLRGVEDLKA-FDAGLSNTTTALDMMRIMEAIALGKV---EGSA +EMVQILSDQYF-KDLIPKLLPPDVKIAHKTGSIT-GVQHDTAILELPGGSRYVLVILSKN +LS-DVPAGKEAIARMSRVIYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Deltaproteobacteria bacterium RBG_19FT_COMBO_52_11 TaxID=1797852 RepID=A0A1F9DSF3_9DELT +------------------------------------------------------------ +-------------------------------LSVQNLLELMLLISDNSATDLLLRLAGGP +EAVTARMRALGIRDMEINRPTIHLIAKFEADPRDTSTPEAMVMLLERIFRGDLLKRESGA +LLLDMMKRCRTGKARLKGILPAETVVAHKTGSLG-GTTNDVGIIALPDGGHIAIAVFVKS +SEKEIQERERAIAQIARAVYDFf +>[subseq from] serine hydrolase n=1 Tax=Bacillus psychrosaccharolyticus TaxID=1407 RepID=UPI00031EA407 +--TIEKDIIELVQLFDGRISYKIEK--DEQVI-EYNSHDIYQSASLIKIPMLVEGFRQVE +KNKIAFTQHVPFIQGDVAGGSGVLSALSNSLLTVKDLLVLMTIVSDNTATNMLISLL-GM +ENFNTCMDDLGMKDTMLQRRMMDFQAA-ADGRENITTAADIVTCLKAIHKGDELLSSSRQ +QILEIMEKQQF-CDKLPAMMGNEVKIANKTGSLD-GVSHDAAIIRYGSET-VYAAILTDQ +IS-SSEESRQLISQIGKLIYD-- +>[subseq from] serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=UPI000A053672 +------ELQNLIQTLPGRYAVFAKNLETQKTF-AYHEHDIFPSASVIKVPILIELYRRVE +EDHLSLDHLLLMRKEDQVGGSGVLKDLTPGTYSLRDLATLMITVSDNTATNLLIDYL-GV +DWVNSTIRRLGTQNTELIRKLQRVPAE--YDQINHTCAYDMALLMEKLARGTAISLAVSE +QMVNLLTRCQVSIAKIPADSVKEVIIAHKTGSLSE-ASHDVGIVYSPHMN-YVAAILSEG +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Roseicyclus mahoneyensis TaxID=164332 RepID=A0A316GX55_9RHOB +-------LELIEISAGTDISVALLDTASARSV-QWNDTARINLDGTVSLLLAAAVLRRVA +EGRDVLDRDV-----------PAAEGLIGQKMTVDALCAAMMTRGDSTAASLVLGVVGGS +DGLTSFLRDIGDVETEVAATAAQGDDATPGSIRGTTTPCQMLRNLERLLLGDGLTADGKA +RLLDWKTSNTTGASRLRAGSPEGWIVADVTGQGAYGETSALAAIFPPDRTPLLMAVYFGR +SPRAPGAQDRYFAELARIATD-- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Calditrichales bacterium TaxID=2528038 RepID=A0A524LC39_9BACT +------------------VAVSFQTADQDQYM-GINDTLSMHAASTMKVPVMMEVFRQVQ +AGKFSLSDSIVIKNESIIDGSLYSYAMIGKKESIRSLVHEMITYSGNLATNLLIGWV-QP +ENVQNLMKQIGANDIQVLRGVEDIKA-FEAGKSNTTTAKDLAIIYQDIYNGSEWTESSRK +EMIDILLDQKF-NKKIPAGLPKEVKVAHKTGSITE-IDHDSGIIYPPQTAPYILVVLTKG +FKE-HERAQETIAEISRRIYAWy +>[subseq from] Beta-lactamase class A n=1 Tax=Falsibacillus pallidus TaxID=493781 RepID=A0A370GP18_9BACI +--RLRDEITQLASVCPGRIGLAIE-THEGKIL--LNEMDRFPSASLIKLPILIECFRQVE +AGKISLDEPVDFSSLKRVGGAGVLPALSDSVLTVKDFMTLMIIVSDNTATNFLIDLA-GE +KEINDCIKTLQLKETSLGRRMMDFE-AIRNGKNNYTSPEDMLLVLKEIDRGKLLNKKSRE +LILQIMKQQQF-VDKLPALMDTEVTAANKTGELD-GVEHDCGIFTYGEK-TVYASVLIDG +LY-DKELGRKTISRIGKAIFDY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A649UHW1_PSEAI +------------------------------------------------------------ +---------------------------------------------------------GGP +AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ +QFVDWLKGNTTGNHRIRAAVPADWAVADKTGTCGYCTANDYAVVWPTGRAPIVLAVYTRA +PNKDDKHSEAVIAAAARL----- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora musae TaxID=1894970 RepID=UPI0011C3A55F +-----GQLQQVVDASTANAGVAVRDLSGDQQI-AVNGAFRPKAASVIKLWILVELLRRVD +CGQVSLEDGVLVTPSQVVNGTGELQHETFPQVTLHRLAEYMIKYSDNTAANVLIDYFGGF +APVNDLIDSMNQRETILARKMLDTEAA-MRGEENYTSPDDVVALLGAVWDAQILTPATRD +LMIGFMAEQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSQ-VAVAFLTSG +PM---AGGDETVRRLARTVYDY- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora musae TaxID=1894970 RepID=UPI0011C35583 +-----GQLQQVVDASTANAGVAVRDLSGDQQI-AVNGAFRPKAASVIKLWILVELLRRVD +CGQVSLEDGVLVTPSQVVNGTGELQHETFPQVTLHRLAEYMIKYSDNTAANVLIDYFGGF +APVNDLIDSMNQRETILARKMLDTEAA-MRGEENYTSPDDVVALLGAVWDAQILTPATRD +LMIGFMAEQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSQ-VAVAFLTSG +PM---AGGDETVRRLARTVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Melainabacteria bacterium TaxID=2052166 RepID=A0A327J8K0_9BACT +---LEDGLKELMKKYTIQPAITVWDFNTGKYV-DINGSEIYPAASIIKVPVLINLFKTIE +ANGLSIYDEMTLTNYYKASGSGNLQYAASGKYTIDKLAKTMIEDSDNSATNMLMSKLGSM +TAVNTAIRSWGIPNTHVQTWLPDLTGT------NFTTTNDMATMLFNLDNPNFLSINSRE +YIVDYMSHVKN-DRLIPQGLGKGATFLHKTGDIGT-MLGDAGIVYMPNGKKYIVVIMAKR +PYN-SPLGKQFIQQASKLIYE-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7UP67_9BACT +-dKLRSRIETVDRGLDGVLGLSVKDLKGGMTL-EIRPQEPFPQASSIKLAVLYELFRQAE +EGRVDLRE-LTRPPLPRVRGGGVLQELGDRLLTWRDLAVLMMGWSDNAATNVLIDRV-GM +EAVNRRLDSLGLRATRLRRKMMDLEAARRG-DENVSTPAEMRQLAEAMYAGAGLSKERVK +DLLAVMAVPKD--SPFRVPLPEDLVVADKPGSLE-AVRCVTAIVDLPGR-PYAVSIMTTY +LRHD-ADGEAAIKQISSALYETf +>[subseq from] Beta-lactamase n=1 Tax=Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10) TaxID=700598 RepID=G8TLL8_NIAKG +-nKLKDQINSRLAEQPGNFAVAFKDLSTGDSL-LINEQDFFHAASTMKTPVMIEVYKQAA +ARRFSLNDSVVLKNESIVDSSLFSYQHLGEKMPLYNLVYDMIIRSSNLATNTVIQMV-NA +RNVTLTMRQLGANKIQVLRGVEDSK-AFDRGLNNVTTANDLMVIYEKMAKGEIVDSASSQ +AMIKILLDQEF-NEIIPARLPKDVKVAHKTGNITH-VLHDSGIVFLPNGKKYVLVILSKN +LQN-EANAKKAMAEVSEMIYRY- +>[subseq from] Beta-lactamase class A n=1 Tax=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) TaxID=886293 RepID=L0DQE0_SINAD +--TLESRLKPLIQAHKGKVSVAIKNLETGESF-LYHEDDPMPTASLIKLPIMIESYRQAE +EKKIDLGEMLTLKQSDKVPGSGILTDHFSAGFPLVDAIHLMIVYSDNTATNLVLDKI-GI +GSTAAFMEKLGYPNTKAHSKVFRRDTRSKKFGLGSTTAAEMIRLCESLQKGELVSKEASE +AMLKHLRACDD-KDKFPRFLPPDTKIAFKTGSVDS-SKTAAGIIECGQG-PVAVCVMTDE +NEDKDNAGNRLCAEVARVVFEHf +>[subseq from] Serine hydrolase n=1 Tax=Ignavibacteria bacterium RIFCSPLOWO2_12_FULL_56_21 TaxID=1798438 RepID=A0A1G0SSS3_9BACT +-nDLLRDLDSLCAESGGAVSIAAEHLDTGERI-LISENDMYHAASTMKTPVMIEVFRQAA +EGKFRLDDSIVVRNDSIVDGSPYSYNLIGKPATILFLIRHMITVSSNLATNILIELV-DA +RKVTETMRTLGAKDMNVLRGVEDGK-AFQKGLNNETNAIDLMTIFKAIAEGKAVGAEEDK +AMVDMLLAQRF-RSKIPALLPEGVRVAHKTGNIT-GVEHDSGIVFLPDGTQYVVVILMSK +LKEN-ATGVRAAAKISRRIYDYf +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A350BIN3_9BACT +-nDLLRDLDSLCAESGGAVSIAAEHLDTGERI-LISENDMYHAASTMKTPVMIEVFRQAA +EGKFRLDDSIVVRNDSIVDGSPYSYNLIGKPATILFLIRHMITVSSNLATNILIELV-DA +RKVTETMRTLGAKDMNVLRGVEDGK-AFQKGLNNETNAIDLMTIFKAIAEGKAVGAEEDK +AMVDMLLAQRF-RSKIPALLPEGVRVAHKTGNIT-GVEHDSGIVFLPDGTQYVVVILMSK +LKEN-ATGVRAAAKISRRIYDYf +>[subseq from] Serine hydrolase n=1 Tax=Runella sp. SP2 TaxID=2268026 RepID=A0A3G3GXN5_9BACT +--SLKETITARLKTVEGEFAVAFKDLQTQETF-FINERENFHAASTMKTPVMIEVFKQAK +AKKFKLTDSILVKNESIVDGSPFKYRQIGKKMTIYDLTYQMIIVSSNLATNILIDLV-DA +KNANATMRQLGAKEIQVLRGVEDTK-AFQKGLNNSVTAYDLMLIFEKIALKKVVNRKACD +EMIRILFDQKF-NEIIPAQLPGIVKVAHKTGSIT-GVQHDSGIVFLPDGRKYVLILLSKK +LVKP-KEGVRALADISRLIYE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Prevotella intermedia TaxID=28131 RepID=Q5XLF8_PREIN +---LTVSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A346QRV4_ECOLX +------------------------------------------------------------ +---------------------------------------------DNSASNMMLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQ------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A5M5C6X4_BACOV +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVAYS-- +>[subseq from] Serine hydrolase n=1 Tax=Pontibacter actiniarum TaxID=323450 RepID=A0A1X9YTN2_9BACT +-qKAEEQLKDIIGRSPAVTGLVAVDLTSGETF-AFNADVAFPQASAIKVPILMSVYKQAH +EGKFLLSDQRKVAPGNIVGGTGILKDLVDTALSIRNLGVLMIALSDNSATNSLIDLV-GM +PEVNAMLRSLGAKQTLVQRKMINSAA-SGRGEENLSTPADAAKILQLLYRGEFINKATSG +EIVSILRKTDRRTSRLATGLPDEVPIAFKPGELN-GVSTEWALVLLPER-PYAVAVMESY +KV--EGQGEETVEELSEVLYDYf +>[subseq from] serine hydrolase n=1 Tax=Nonomuraea indica TaxID=1581193 RepID=UPI000C79E95A +------DFAAVFRAAGVTGYLHALDIDSGKEL-GHGSDEPMPTASVFKVPLMVAFCRQAD +AGLLDPGERVTVRAAERVFPTGVSAMLDDVTMSLRDLAYLMIAVSDNTAADVLLHRV-GL +DAVNAMLTTFGLRVTHVQQSIADFYRVLDPWHTNRSTPREMAALLSLIWRDEAASPASCA +WMRAVLNKQVW-PHRLASGFPDDVDVSGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRS +FSVNQPRADAVIGTAARMAVDH- +>[subseq from] serine hydrolase n=1 Tax=Cystobacter fuscus TaxID=43 RepID=UPI0012DFCE9D +-----------------------------DAL-YLEADRSFHAASTMKVPVMLEVFRQVD +AGTLSLEEPVTLTRESIVDGSPYVHERLGQSVPLRELVERMITRSSNLATNLVLSRV-DA +RRVTKTLRALGARRMTVLRGVEDGK-AYAQGLNNTATARDLASLLSALERGRAASPASTR +AMRSILLAQEL-NREIPAGLPPGTPVAHKTGQIS-GILHDAAIVYPPGQPAYVLVVLTRG +IP-DEAVARSLIVELSRQVYAH- +>[subseq from] serine hydrolase n=1 Tax=Rhodothermaceae bacterium TaxID=2026787 RepID=UPI000DD37AA0 +-----------------------RDPHTNTRY-DFHAERLFHAASTMKVPVMIEVYRQAE +AGRFSLDDSLLVRNTSIVDGSAYRYRMLGRRMAIRDLVHRMITVSSNLATNLLIDLV-TA +DSVQATAERLGVRHMQVRRGVEDLLA-FRQGLNNTATAADLAVLLDALRRGAAVSPEADR +AMIDVLLDQQF-GDLIPAGLPPGVRVAHKTGAITR-IHHDAAIVYPERGPAYVLVVLTEG +IE-DQARSAELVAEVARGVH--- +>[subseq from] Serine hydrolase n=1 Tax=bacterium TaxID=1869227 RepID=A0A522YQY4_9BACT +--AMTAELQRTASSSRWRTALYVKDLQRGYEW-TYHAEDLFPAASLIKLPIMVGVFEKIQ +RGQLSLYSKLKLRRTTRMGGSGSLKWQRDGTYTVRYLLEKLIKESDNTAMLLLLDEV-GI +GFLQQYFPQMGLVYTEINSDGLRLDSG-GVRAENYTTAREMGAVLERIYRGELVNGFASE +LMLDILKRKRA-RSRLAKYLPPGWQIAHKTGLLRR-SCHDASIVFSPNGD-YVLVVLTGR +VD-SYPAAKDFIARLGKTTYRTy +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Butyricimonas TaxID=574697 RepID=UPI0007FB2B2B +---LTDTISKIVSGYPGEIGVAVI-INNMDTV-TVNNKSIYPMMSVFKLHQAIAVCNDFD +RKGLSLDSLMCIKRDELDPWSPMMKEHPEPVLTVKDLLRYTLIQSDNNASNIMFKELVSV +ARTDSFIATIPRTSFRIAYTEGEMSVDHDKAYSNYTSPLGAAMLMNRLFTDSLVSREKQC +FMMNTLEECITGKDRIVAPLKEGITIAHKTGSGYNGAHNDVAYIRLPNNVCYSLAVFVKD +FKGNEAQASKAVARVSAIVYA-- +>[subseq from] serine hydrolase n=1 Tax=Thermorudis peleae TaxID=1382356 RepID=UPI00068CFDCE +----PSQIAERIAHFPGQISLAASDLDRDWHL-AFRADNTVPSASVIKLLILAELYRQAS +RGALSLEAQVAIEQEHVVEGSGVLRWLSGLRFTVRDLATLMIIVSDNIASNRLIDIL-GF +AAINHLAAQLGLQQTSLRRPFWGRA-ARADEPENTMSARDAVALLRALECGMIVPEPLLD +EVRTILRAQQF-QECIPACLPPSVVVGNKTGSLP-GIAHDAAIIWAPQGR-LALAIFTTG +LT-DEHRGRCEISEIARACYNAw +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A174URT6_9BACE +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGCNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Luteimonas aestuarii TaxID=453837 RepID=A0A4R5TL46_9GAMM +--ELERRLEAVDAAYAGDIGVYVRHLGRDESF-SYRAEEPWYLASGVKVPIAIAVMRAIE +RGELALDTRVTLRESDFVDGAGGTNAYRAGTLRVSWLLEQMIVHSDNTASDVLIRTV-GI +EQVNRVAAELGRVDGMHITTLADVRRAYYATHANSASLVEFGRMLAALSEGRALGAEGTT +YLLDVMSRVQTGSRRIRAGLPAGTRFEHKTGTQHR-RTCDLGIATVPGRARVVIAACARG +T--ATAAGERALRDVGAAVT--- +>[subseq from] Serine hydrolase n=1 Tax=filamentous cyanobacterium CCT1 TaxID=2107702 RepID=A0A2P8VTW4_9CYAN +---LKGELENLATLTPGTPVAFAVDLDSGQYI-DLGGAEPVAAASTIKVPILIAFLQQVD +AGTVALNQSLMLQEEYMAGGSGTLREAVGTEYTALDVATRMIVASDNTATNMMIAALGGI +EALNQTFAGWGLEHTVLRNPLPDLDGT------NTTSAKDMALIMALVDQGGLLTPRSRD +RLFSIMQRTEN-VSLIPSGISDRSLTAHKTGDIG-GLLGDVALVDVPNGKRYTLALLVQR +PTND-GRASELIRRMTETVH--- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Melainabacteria bacterium 35_41 TaxID=1897008 RepID=A0A1Q6U3F7_9BACT +-----SSLRNLSAMYSIHPSIYVWDYETGNYA-DVNANEIFPTASIIKLPVLVQLFRSIE +KNQLTIYDEMPLTEYYRTEGSGSLQFKSANSYTIDTLARMMITESDNSATNMIMARLGSM +TDINQGIREWGLKHTYVQTWLPDLGGT------NHSTARDMATILYNIDNPKFLSTSSRE +KIFDYMGHVHN-NRLIAAGLPAGAEFLHKTGDIGK-MLGDAGIVYAPNGKKYIVVIFANR +PHN-SPLGKEFIVKASEIIYN-- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella intermedia TaxID=28131 RepID=Q8KT54_PREIN +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMVMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Archangium sp. Cb G35 TaxID=1920190 RepID=A0A1Q3HPX3_9DELT +----RASLQEIAQVKGATVAVAYQHLGNPKDSlFLEAERSFHAASTMKVPVMIEFFRQVD +AGKLSVGQELTLTNQSIVDGSPYAYERLGKPVPARELVERMITRSSNLATNTVIALV-DA +KRVTKTLRSLGARQMTVLRGVEDGK-AYQKGLNNTATARDLATLMAAIEQGRAASPASTQ +AMRTILLAQEL-NLEIPAGLPPGTPVAHKTGQIS-GILHDAAIVYPSGKSPYVLVVLTSG +IP-DEKVARSLIADLSRQVHA-- +>[subseq from] Class A beta-lactamase n=2 Tax=Porphyromonadaceae bacterium TaxID=2049046 RepID=A0A3B8QUV8_9PORP +--ELESRIGRYIADKDARIGVAVI-IDGRDTA-EVNGSQFFPMLSVYKFPQALAVAEHCR +RHGVGLPDTVRVSADEMKSWSPMRDRFGAVNLPLLALLEYSLQQSDNNACDVLFRMIGGP +AVADSLMNKWGYGDIRIRSTEDEMHRDTDLCLVNCCTPLEMARLLDDFNTGIRLRSEENR +AIASLMESCVTGRDRLARPLTTPAILGHKTGTGDVDAVNDAGYVNLPDGHRYAVAVFMAS +SAYGLEDTSRMIADISEIVYS-- +>[subseq from] serine hydrolase n=1 Tax=Spirosoma agri TaxID=1987381 RepID=UPI0013DBCD62 +--ALRQRIDRELNQQTGVFAVAFKDLTTGNEL-LIREREVFHAASTMKTPVMIEVYNQQA +QGKLALTDSILIKTESIVDGSPYTYKQVGSKRTLASLVYDMITVSSNLATNLVIERV-GA +PNVVQTMRDLGASDIQVRRGVEDTKA-FAKGLNNSTTAYDLMVIFDKIATGQAVNAEASK +AMIATLLDQKF-NDAIPAKLPKAVKVAHKTGSIN-GVRHDSGLVMLPDGRRYVLVLLSKD +IT-DDKAVINAYATVSAWIYQ-- +>[subseq from] Serine hydrolase n=2 Tax=Bacteroidales TaxID=171549 RepID=A0A3N2M6T1_9BACT +-qELQQLVDSLVRDVPGTVGVAVI-TSEGDTV-AVNNDVRYPLMSVFKLHEALAVAHELD +SRNQSLDSIMTLQRSQLSEWSPMLKDYPKGDISVGELMRYILTVSDNNASNVLFDSIVSV +SHTDSFIRNLGIDSFRLQYTESQMQRDHAISYDNYSSPLSCAALVKRVFTDSIVSQEKQD +SIRQWMGKCVSATDRMMEGVADGARLYHRTGSGYTNAINDVGYIIMPDGRETALAILVKD +YPGEQSQADSLIASITTSIL--- +>[subseq from] Beta-lactamase class A n=1 Tax=Chthonomonas calidirosea (strain DSM 23976 / ICMP 18418 / T49) TaxID=1303518 RepID=S0EUC6_CHTCT +-----ADVAAIEKASTGVLCFAAEDLQTRKVV-QHNAEHKCRTASVIKLPILVHVGLEVA +EGRRAWEEPLVLTDEEKVPGSGILSQLTAGLLTLRDVCVLMIVLSDNTATNMIIEHIGGV +NPINARMRALGLETTTCFRKVYARDALPNPYGLGVTTPREMLQLLEMIATGSLGSEALCE +EFLAILSKQHY-RDCIPRYLPEEWRYAGKTGSIDE-ARNDVGIVTDAVGNRFALALFCQE +LQ--------------------- +>[subseq from] serine hydrolase n=1 Tax=Acidaminococcus fermentans TaxID=905 RepID=UPI000D0FDA46 +----------------GPAQVYFTDLATNQSL--YRGSSTLPSASMIKVFILARAYEDLR +NGSLSRKKTFTLTPENVVGGAGVLQGRPYGTVPLQEALDLMITESDNTAANLLIDRL-GM +DRINSYLQSHGYSHSVLRRKMMDTKA-MEEGRENMTSTRDVALLFKRLYRGNCVGPAQDR +EMLEIYKRQTD-NDSIPGDLPQGTVVAHKTGEVSD-VRHDGGIVYTPKGA-YVLVIFTRN +YTP-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7KVT4_9BACT +--SLRARIEARIAQAPARVGVYYRDLTSSDSL-TVGALTRFHAASTMKIPVMIQLFRDRD +AGLLSLDDSITITNTSIVDSSPYQYKRLGQRAPIRELIELMETVSSNLATNLLITKV-DA +KRANATAHALGADSILVLRGVEDGK-AYRAGLNNTTTARDLGMLLAAIATGKAAAPASCR +EMLETLGRQHF-NEGIPAGLPAGTTVYHKTGWVGQVVYHDAALVEAPHGGKYVLVVTTGG +IQKD-DDAHALVRDISKLIFD-- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8U8C6_9BACT +--RLEANVIRITKSVNARWGIYMKCLETGEEI-AINADDQMDTMSVIKIPLMVEAFRQIE +AGKFALSDRVTITDSAKRPGTGVIRSMDAGALTIKDLLTLMIIVSDNTATDLMYEKVGGV +EPVNRLMESYGLKSIRAMGTAEMWFSQQGRTPFGLSSPRDMGRLLENIEKGEAVSKSASD +QMLQIMRGQVY-GSRLPKYVT-GYRVPHKTGDFLPYIGNDVGILESPHT-NIVLSVFTAH +HFGIGANLEDAIGRIAELVANYy +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Sphingobacterium daejeonense TaxID=371142 RepID=A0A4U9JPN8_9SPHI +--------------------------------------------------LHWQFLDLVD +KGKLSLDQTVKVGKKDLMPWSPLRDENPNGGFTIEKLIQYAVSHSDNTACDVLIKLVGSP +KDVEKYFKKNNIQDIQITYNERDMQAKWENMFQNWTTPKAASKTMMLFYEKEPISKNSYF +VFWRTNFETTTGEKRIKGKLPVGTHVAHKTGWSGTAAVNDIGIVVLPNDQHFYISVFITE +SKENFDSNEELIADIAKAAYDYf +>[subseq from] serine hydrolase n=1 Tax=Negadavirga sp. SW125 TaxID=2164132 RepID=UPI00130078C0 +--------------------------------yAQNENKQIPSASIIKVPILIFLFMEVD +KGSLDLDEKVVLEEKDKVGGAGMLRENPDGSFTWRYLATEMIRISDNTATNMLINRL-GR +TRIQTWLEEEGFKHTILDRLMMDFE-AIAEGRQNFTSPNDTNRLFMGLYNGQWLTENSKV +EALFMLKNCAD-NTCIPGQLPPGVEIAHKTGTLDY-VRGDAGIVFG--TSPIFLSVFVEG +FK-ELTEAESIIAEISRIVFEE- +>[subseq from] Beta-lactamase class A-like protein n=2 Tax=Acidaminococcus fermentans TaxID=905 RepID=D2RJL4_ACIFV +----------------GPAQVYFTDLGTNQSL--YRGSSTLPSASMIKVFILARAYEDLR +NGSLSRKETFTLTPENVVGGAGVLQGRPYGTVPLQEALDLMITESDNTAANLLIDRL-GM +DRINSYLQSHGYSHSVLRRKMMDTKA-MEEGRENMTSTRDVALLFKRLYRGNCVGPAQDR +EMLEIYKRQTD-NDSIPGDLPQGTVVAHKTGEVSD-VRHDGGIVYTPKG-SYVLVIFTRN +YTP-------------------- +>[subseq from] Beta-lactamase TEM n=1 Tax=Clostridium neonatale TaxID=137838 RepID=A0A650M7L0_9CLOT +---LTNRINYIIKNSSADIAVLVKDLKEDKVIfKYNEDKKYVSASIIKVPIMIEALSRVD +LGEINFDDKFNIGDDNKVDFSVITEQDLK-ECTFEELIEWMIISSDNTATNVLIDIL-GL +ENINDRIKKLNMKNTLLERKMMDFK-AIEYGRNNYTSLNDMLIAMEGLYRGVLISSEMSL +KAIDILKNQRD-NFMLKRYIRDNVTLANKTGELDK-LNNDVGIFYTKNHN-YFIGIFVHD +VKKN-KDAYEIIGKISKEVYDYy +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6DSG3_9BACT +------------------MGLAIVDLIDGRTI-LRNADREFPTASSIKIAILLELYHQDQ +QAKAKLDDVYDFDPKELVEFSQIMSGLTPGVVTNRDLAQFMVAVSDNTAANILIDRV-GK +DNVNAMLRGLGLTKTMLRRKMMDFAAA-RRGEENVSTPQEMTRLLEAIYKSKLLNKELNQ +QLIKQLSTLKE--SYIPHDLPAGVQVANKPGNLQN-VRTDSGIVFVKDH-PFAMSVMTSN +AR-DERAAERAISEIALEAYRYf +>[subseq from] Beta-lactamase n=1 Tax=Prevotella denticola TaxID=28129 RepID=Q8KT55_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNGFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] serine hydrolase n=1 Tax=Leptolyngbya sp. PCC 7376 TaxID=111781 RepID=UPI0013580CAD +--------------PELDATMLFVDLDTGEYL-DVASSRSISAASTIKIPVLVAFLEAVD +QGTVQLQDSLIITDNVKGGGSGNFQYKDNGTLSALFVASEMSINSDNTATNMIIEQLGGF +EVLNQKFQSWGLQQTQLNAPLPDLEGT------NLTTARDLAFLLAKISRGDILSNRSRD +RLIRIMSSTRN-DNLLPQTLGQGAAIAHKTGDIGY-IIGDAGIIDLPNGKRYIASIFVER +PY-DAPKGKELLHKIGKLFYQH- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium oryzae TaxID=1450648 RepID=A0A1V4IA85_9CLOT +----EKAIIDYMKNKDIQYSLVIKDLHNDECIiDVNGNTKIQSASIIKLFIMARAFEMTE +NGELSLEERIAITKKERIPYSIVYLLDENTTYTIRDLITLMIIQSDNTATNVLIERL-KM +SNINDFNARYGFTKTSVKRKMLDFETR-EAGIDNETSAADAARFLQLAYKGKLVSEKASE +QMLEIMKNQLD-YSMMKLDLPDDVIIAHKTGDLTN-IKNDVGIVYSNKGD-YIFSMFTWN +AK-SDNYARNVLGRVSSMFYSYf +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6IGM4_9BACT +------------------MGLAIVDLIDGRTI-LRNADREFPTASSIKIAILLELYHQDQ +QAKAKLDDVYDFDPKELVEFSQIMSGLTPGVVTNRDLAQFMVAVSDNTAANILIDRV-GK +DNVNAMLRGLGLTKTMLRRKMMDFAAA-RRGEENVSTPQEMTRLLEAIYKGKLLNEELNQ +QLIKQLSTLKE--SYIPHDLPAGVQVANKPGNLQN-VRTDSGIVFVKDH-PFAMSVMTSN +AR-DERAAECAISEIALEAYRYf +>[subseq from] Beta-lactamase enzyme family n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KNZ6_9BACT +----------------------------------------------------LAVLDKMD +KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI +DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKHPLFGTQYKD +FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME +SQENDADNAAIIASISKIVYDT- +>[subseq from] serine hydrolase n=1 Tax=Nocardia otitidiscaviarum TaxID=1823 RepID=UPI0011DE2CCF +----ETRIRAVFADAGCTGWLHARRCDSGTEI-SLGGDERVVVASVYKLPLFVAFCRHID +AGRIDPTARITVTPSDCTPPTGIAALRDPVTMSLRDLAASMMTVSDNAAADVLLGEI-GL +AAVEELLDDLGLIRTRIIGGTADLHRAYDPSYTSATTPEEMTRFLHALWRGDILSPERTD +YARAVMRAQVW-QHRIAAGFPRSVTVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLPAVDAAIAEVARIAVT-- +>[subseq from] Class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4Y8E2E6_ECOLX +------------------------------------------------------------ +--------------------------------------------------------MGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase, putative n=1 Tax=Leptolyngbya sp. PCC 7376 TaxID=111781 RepID=K9Q5U0_9CYAN +--------------PELDATMLFVDLDTGEYL-DVASSRSISAASTIKIPVLVAFLEAVD +QGTVQLQDSLIITDNVKGGGSGNFQYKDNGTLSALFVASEMSINSDNTATNMIIEQLGGF +EVLNQKFQSWGLQQTQLNAPLPDLEGT------NLTTARDLAFLLAKISRGDILSNRSRD +RLIRIMSSTRN-DNLLPQTLGQGAAIAHKTGDIGY-IIGDAGIIDLPNGKRYIASIFVER +PY-DAPKGKELLHKIGKLFYQH- +>[subseq from] serine hydrolase n=1 Tax=Olsenella sp. oral taxon 807 TaxID=712411 RepID=UPI00067D6659 +--AVRAAVEPLVSPYGDEVAVVYTPVDAPDGGfAINGDERMRSASMIKTLIMATLLQHEA +DGSISLGDSYTIRESDIVGGTGSVQSMGAGTLSLSRLAELMISQSDNVATNVLIDRL-GM +GTVNDEGARLGLGQTVLARKMMDTAAA-AAGRENYTSASDQARILRLVASGDLASPEASQ +AALAWLKEQED-SEGIAQGVPSGTVVAHKTGTLDS-VRHDGAIVYG--KRPYVLVIMTHG +MS--DGAANSLMARVSRTVWD-- +>[subseq from] Serine hydrolase n=1 Tax=Cytophagales bacterium TaxID=2053541 RepID=A0A355BVB8_9BACT +---LIADIRGYLPKDNGIYAVAYLDISSGEKI-LIHEHETFHAASTMKTPVMIEVYKQAA +EGKFSLNDSIEIKNESIVDGSPFSYKMIGRKKTIYDVLYGMIIASSNLATNILIEKV-DA +QNVMETMRSYGAHDIKVLRGVEDTKA-FRQGLNNQVTANDLMLVFEKIARGEAVSPEASE +AMVKILLDQKF-NDIIPAQLPKDVKVAHKTGWIT-GLHHDSGIVMLPNGKKYVLVLLSKE +LK-DEKAGVEALATVSKMIYDY- +>[subseq from] Serine hydrolase n=1 Tax=Balneolaceae bacterium TaxID=2053516 RepID=A0A6C1P5L2_9BACT +-----------INTVDGDMAVVMLGMDDAAGHvLINENERFHAASTMKTPVMIEAFKQAE +EGKFSLEDSILVKNESIVDGSPFSYDKLGTRVPMRDVIYDMITRSGNLATNLMIDLV-GA +ENANRTMHDLGAVNIQVLRGVEDMKA-FDQGLNNETTAMDLAIIYREIAGRSVVSEQACD +EMIAILKDQHF-RDMIPAGLPDDVQVAHKTGSIT-GVKHDSGIVYLPDGRSYVLVILSKN +LSNN-DDGRDAGAEISRLIYEHy +>[subseq from] Serine hydrolase n=1 Tax=Flavihumibacter sp. R14 TaxID=2705549 RepID=A0A6B3PR01_9BACT +---IKEKISREFLSVQGTFALALKDLQTGEEI-LINERETFHAASTMKTPVMIEVYKQAA +AGKFNLSDSVTIHQNSIADGSEYIYKLKGSKMDIYGLLYRMIIRSSNLATNMIIELA-GA +KNITRTMRDIGANDIQVLRGVEDIK-AYEKGMNNTTNAYDQMLIYSALANGKIAGIESTK +PMIDILLKQEF-NEMIPARLPKDVKVAHKTGSIT-GIQHDAGIVYMPDGRKYVLVLLSKD +LK-DEKEGIAVMSRVSELVYN-- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Siphonobacter TaxID=2635712 RepID=A0A2N7B4W1_9BACT +--SLKEQIQHYLSGRKGTYAVAYKNLATGEHV-YINENDSFHAASTMKTPVMLEVYRQAY +KGKFSVLDSIVVKNESIVDGSPYSYEKVGQKRTIYDLMYEMIIYSSNLATNIIIDLV-DA +RNVTKTLCKMGAKHTQVLRGVEDKK-AFAQGLNNKVSAYDLALLFEKIAKGKAVSPEASQ +AMISILLDQKF-NSVIPAKLPKSVKVAHKTGSIVS-IMHDSGIVYLPDGRKYVLVLLSKN +WQPDREAAVETMATVSEMIYQ-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SBF9_9BACT +-dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKLD +KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD +FLLNTMIETTTGPKRLK-GLFAGW------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Lunatimonas lonarensis TaxID=1232681 RepID=R7ZPQ9_9BACT +--KLNQEIKALFEETAGDFAMAFRLLNTTQTL-LINERESFHAASTMKTPVMIEVFKQAE +EGRFSLSDSIPVINESIVDGSTFSYSRIGLQASIYDLTYQMIIKSSNLATNLLIKLV-NA +KAVTQTLRELGAADIQVLRGVEDQK-AFDAGLSNTTTALDLMLILEAIATGNAVNREAST +EMMKILGDQYF-KDLIPKYLPETVRVAHKTGSIT-GVQHDSAILELPDGKRYVLVLLSKN +LT-DAAAGKETIAQVSKLVYEY- +>[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013307591 +------------------------------------------------------------ +------------------------------------------------------------ +----AFARAIGEETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ +PQQNAERRRDVLASAARIIAE-- +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. B2A1 TaxID=2081964 RepID=A0A2S0JQ72_9BACI +----ERAIQRVLDEAPYNVHVFVKDANTNHYFiQEKFQAVFSSASLIKVPILLGVLHYLE +GNNQDIHQEIEVAPKEWVDYSVISEQRIEQ-STIYELLVWMIITSDNTATNVLIDFI-GI +DVFNHYFSQIGLHQTKLQRKMMDFEK-LERGIDNLTSANDMAHLFSRIYQQDLLSTKFSK +LTIDILSRQRV-HESLKRYLIDDVKMAHKTGGLET-VDHDVGIVYNGSN-DYLIGVFITD +VI-NNEYAKQLIGRISKIVYEHf +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7IRU6_9BACT +----REQLAARVARAPATVGVYYKSLSRPDSL-LLGANLRFHAASTMKVPVMVQIFRDAD +EGLLRLDDSLAVHAASLVDGSPFEYRRVGGKASIRELLELMITRSSNLATNLLIERV-GA +ARAQASARGLGAWSIQVLRGVEDGK-AYRAGLNNTTTARDLGALLAAIAQHRAASPSSCE +EMLRILGRQEF-NEGIPVGVPPGTRVAHKTGWIGEVVYHDAALVYPPSG-SYVLVVLTGG +IKED-SVAHNLVADVSRMVWE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Lihuaxuella thermophila TaxID=1173111 RepID=A0A1H8FFP9_9BACL +-qKLREQLEEWKLKLPGRWGVWIEDLTTRDSW-EWNGDHSFYAASVIKVPIMVAVFREAW +KGRFALSDEMTLTPEAQVGGAGVLQHLTPGLVSIRDLTTLMIIQSDNTATNLLIELV-GK +DAIHEAMTELNMNGSRFYNPLMILPADR--EGVNTITPRDLASCYRKIAKGEAVSYHASL +QMINILKKQQI-RDCFPSLLPQTWELAHKTGTVTR-VLHDTGILYTGSHA-VIMVALSED +CS--YREAKEQLAQLAFRVYQAy +>[subseq from] serine hydrolase n=1 Tax=Muricauda sp. 40DY170 TaxID=2499163 RepID=UPI000F8CE039 +-eALETKVQTQIDSIEGDVAVAFLNLSDPTDTlFINQNEEFHAASTMKVPVMIELFKQQA +SGKINLNDSILLVNESIVDGSPYRYDKIDTKVAINDLMYSMITVSSNLATNVLIELV-DA +KKVTATMRDLGADKIEVLRGVEDIK-AYELGLSNSTTAKDLLVIMESIATNKAGTETDCK +AMVDILKDQQF-NDMIPAKLPKAVEVAHKTGSIT-GVHHDAGIVYLPDGRSYVVVLLSKN +LK-DFDKGTEQLADISKTIYDY- +>[subseq from] Beta-lactamase n=2 Tax=Luteimonas sp. FCS-9 TaxID=1547516 RepID=A0A0H1AUH6_9GAMM +--ALDRRLRAVDARLSGEIGVYVQRLDDDATW-GLRADESWYLASGVKVPIAIAVLREIE +QGWLTLDTQVALRDDDFVDGAGGTNAHRAGALPIAYLLEEMIVHSDNTASDVLIRTV-GL +GQVNAVAAELIAAQGVRITTLSDVRRSYYATHVNSATLRDYGRMLAALQRGQALDPAGTR +QLLGLMARVQTGTRRIRAGLPPGTRFAHKTGTQYR-RLCDSGIATLPGAHPAIVVIVACV +RGADTQAGERALREIGAAVA--- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A537HUS7_9BACT +---------------SAQFGVAFKNVQTGETL-LMNEKESFHAASTMKTPVLIELFKQAS +TGKFSMSDSIEIKNNSIVDGSEYSYKVIGQKRTIADLAYNMIILSSNMATNMLIELV-TA +DSVMKTMKSLGAKDIQVLRGVEDSK-AFEKGLNNTTTAYDQMLLYNLLAKEKLVNKEASN +EMTRILLDQKF-NTVIPAKLPPEVKVAHKTGSIT-GVQHDAGVVILPDGRKYVLVLLSRF +KKEDEKKVIEAMAAVSKLVYDY- +>[subseq from] Beta-lactamase class A n=2 Tax=Pseudacidovorax sp. RU35E TaxID=1907403 RepID=A0A1N7D2A4_9BURK +-----TAVQQLDSHPQTGLGVYVLDLATGQSF-GHRAEERWYLASMVKVPVAIAVLQAVE +RGDITLDTTVTLRAGDRVDGAGATLRQPGASLSVRWLMGQMIIYSDNTATDMLIDLV-GL +QAVNGVVQALAPRGIARITPLAEVRRAYYAEGLNSGRLDAYAQILVALAEGRALGAEATQ +TLLKLMEDVATGPQRLRAGLPPQARLAHKTGTQRR-RICDAGLVRMPARHPVALVACVRD +AP-SLTRAEHLLAQTAAALC--- +>[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A251XXF7_9MICO +--AADAAFTALEERFDARLGVHLVDTATGAEV-SWRADERFAYASTIKAPLAAALLDRVG +--IAGMDRAVPIEAADVLSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP +AELDAALTALGDETTVVSRREPDLNEATPGDDRDTTT----------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium sp. CAG:768 TaxID=1262838 RepID=R7HYF1_9CLOT +---LESQLNNLASMYSIHPSIYVWDYETGNYV-DINANEIFPTASIIKLPVLVQLFRSIE +KNQLTIYDEMPLTEYYRTEGSGSLQFKAANSYSIDTLARMMITESDNSATNMIMARLGSM +TDINSGIRQWGLKHTYVQTWLPDLGGT------NHSTARDMAEILYNIDNPQFLSTSSRE +KIFDYMGHVHN-NRLIAAGLPAGATFLHKTGDIGK-MLGDAGIVFAPNGKKYIVVIFAHR +PHN-SPLGKEFIVKASEVIYN-- +>[subseq from] serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=UPI00037AEF7E +------ELQNLIQTLPGRYAVFAKNLETQKTF-AYHEHDIFPSASVIKVPILIELYRRVE +EDHLSLDHLLLMRKEDQVGGSGVLKDLTPGTYSLRDLATLMITVSDNTATNLLIDYL-GV +DWVNSTIRRLGTQNTELIRKLQRVPAE--YDQINHTCAYDMALLMEKLARGTAISLAVSE +QMVNLLTRCQG-PVSIAKNPTKEVIVAHKTGSLSE-ASHDVGIVYSPHMN-YVAAILSEG +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. HV4-5-A1G TaxID=2004595 RepID=A0A5M9NXU7_9CLOT +---------------KLNCAFMVENLKTGEKA-AYNEKVVVPSASLIKIPIMMEVFKQVK +EGKLSLKQRITVENDVKVPFSILNLLESGSSYTLKDIITLMIIQSDNTAANILIDLA-GM +DNVNDYIKSLKIKDTTLQRKMMDSLAR-KEGRENKTTASDMVKFFEIIYRGEKSGEPYSI +MMKDILINQLD-NSVMRLDVPDETTIAHKTGDLD-GISYDVGIVYLPNVD-YIFCGLTWN +AV-TNNFARKTIGRISRIAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. 21C1 TaxID=1843690 RepID=A0A1E4V4X2_9PSED +-aELQERLERLDAESPGKLGVYVEHLSEGH-L-DYQAEGPWYLASTVKLPVAIAVLQGVD +KGRLSLDQAVELTAEDKVDGSGGTWSDVGTTFSIRTLLEEMLRESDNTAADMLIRLV-GV +DTLNASLERYGFSQTSLLQVRQDLYAELHPDARNLS------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. 21C1 TaxID=1843690 RepID=A0A1E4V4X2_9PSED +------------------------------------------------------------ +--------------------------------------------------------I-GP +ERVQALANALGLTPGQLEQDLDEAYRRYYAQGRNSSSLTGYGALLRDLVRGELLSDASQQ +LLYQLTGLNQYEAYRLEAGLAEDLPFIQKTGTQQ-GRACHVGVARPETPEQALIIIACAA +DLDENREAGALFERIGEAIQ--- +>[subseq from] Beta-lactamase class A n=1 Tax=Acidaminococcus fermentans TaxID=905 RepID=A0A1I5GMB2_ACIFE +----------------GPAQVYFTDLATNQSL--YRGSSTLPSASMIKVFILARAYEDLR +NGSLSRKETFTLTPENVVGGAGVLQGRPYGTVPLQEALDLMITESDNTAANLLIDRL-GM +DRINSYLQSHGYSHSILRRKMMDTKA-MEEGRENMTSTRDVALLFKRLYRGNCVGPAQDR +EMLEIYKRQTD-NDSIPGDLPQGTVVAHKTGEVSD-VRHDGGIVYTPKGA-YVLVIFTRN +YTP-------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus chordae TaxID=237019 RepID=A0A2W7RTF4_9BACT +----LSTIDAQLDSIQGDVAIAFYNLSSTDRL-MINAEEEFHAASTMKVPVMIELFKQQR +AGKLNLNDTILLKNESIVDSSRYSYGKIGTKVSLNDLLYPMITVSSNLATNVLIELV-GA +KNVTATMRNLGADKIEVLRGVEDQK-AYDLGLSNSTTAKDLMIIMKAIATNQAGTPDDCE +KMISILKDQQF-NEIIPAYLPKDVSVAHKTGSIT-GVHQDAGIVYLPDGRSYVLVLLSKN +LE-DFDQGTDQLARISKTVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Anaerolineaceae bacterium TaxID=2024896 RepID=A0A419EFS8_9CHLR +------RLENFISQFGKTVSTAVYDLQTGDEI-LIGADVTMHPASTMKVPVMMEMFRQAE +AGLLSLDERLTIFNSSIVDGSEFSYARIGESETIRKLNRLMIIRSSNLAANLLMERV-GT +SRVDAFIKELGIADMTVIRGLEDKK-AYRLNMNNSASARSSTHMLRLIVEGKVVSKEACD +EMIRVMLGQEF-NESIPALLPADVKVAHKTGWSSD-FFHDIGIVFPPRRKPYVISLFTQG +FPNDESQAHDCMAQISKMIYE-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus shackletonii TaxID=157838 RepID=A0A0Q3X0I1_9BACI +-------------TTGGTWGIYLEDLDKNETW-SWNENEVFYAASIIKVPIMAAVFSAFD +EGLFKLSDTIVLKREELVEGGVLQHLTPGIRLTIYDYLTLMIIQSDNTATNVLIDLV-GV +EKIQEMMAEIGMRNSCFYNKLNTVPVK--TNGRNMITARDMAVLLKKLTSGMIISQYACE +QMIDIMKKQQF-RDCLPYKFPQEWEFANKTGWVT-GIRHDIGVLYVGRR-TMNIVVLSKD +VE--DKLAKQTMAQIGECIFNY- +>[subseq from] serine hydrolase n=1 Tax=Acidaminococcus fermentans TaxID=905 RepID=UPI0008952775 +----------------GPAQVYFTDLATNQSL--YRGSSTLPSASMIKVFILARAYEDLR +NGSLSRKETFTLTPENVVGGAGVLQGRPYGTVPLQEALDLMITESDNTAANLLIDRL-GM +DRINSYLQSHGYSHSILRRKMMDTKA-MEEGRENMTSTRDVALLFKRLYRGNCVGPAQDR +EMLEIYKRQTD-NDSIPGDLPQGTVVAHKTGEVSD-VRHDGGIVYTPKGA-YVLVIFTRN +YTP-------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=A0A0Q2LV61_MYCGO +---------------HADVAVFFRPLGGGSEW-SYKPDDTFHAASTMKVPVMIELFHQAR +QGKLALDDPLLIHNESLVDGSAFYYRSEGQTRTLRELCELMITMSSNLATNLLIKKL-GI +ENIRATVHLLGADGMNVLRGVED-NKAYDLGLNNTTTARGLAILLTAIAQGKVVDPDSSR +QMVEILKRQHI-NDGIPSGLDPTIPVAHKTGTLK-GIHHDAAIVY--GRQPFVLVILVRG +MTNS-EDSSALMADITRVFYR-- +>[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. Root487D2Y TaxID=1736547 RepID=UPI0006FD5C92 +-qKMTADFQPIADRVPGHLGVAVEDLGTGQII-SFNGERRFPLQAVFTAPLGAAVMAEVE +AKRLRLDDILLIEDVDLSPPSGVADLWAGPMYSVQDLLERAIRDGDNTAADILMKRIGGP +GAVTAWLQGRKVNALDIDRYQRQLQPAYLADPRDTATPLGALRFLEAVNQAELLGPDSRR +LLGRIISQTRGGAGRLRAAVPEGGRLNHIPATARTDVVNDIGVYTLKDGRKFAVVAFISG +SPLPVAEQEKAIADVGRVVIK-- +>[subseq from] Beta-lactamase n=1 Tax=Fusobacterium sp. CAG:439 TaxID=1262899 RepID=R7J4T0_9FUSO +---LENQLNNLSAMYSIHPSIYVWDYETGDYA-DINADEIFPTASIIKLPVLVQLFRSIE +KNQLTIYDEMPLTEYYRTEGSGSLQFKAANSYSIDTLARMMITESDNSATNMIMARLGSM +TDINSGIREWGLKHTYVQTWLPDLGGT------NHSTARDMAQILYNIDNPQFLSTSSRE +KIFDYMGHVHN-NRLIAAGLPAGATFLHKTGDIGK-MLGDAGIVFAPNGKKYIVVIFAHR +PHN-SPLGKEFIVKASEVIYN-- +>[subseq from] Beta-lactamase class A n=1 Tax=Lutispora thermophila DSM 19022 TaxID=1122184 RepID=A0A1M6FJQ9_9CLOT +----DQDIMKSFQNDVGNVSIVLKDLKNDALMfQLDPHRVVASASTIKILIMIEALRQIM +EQRLSFDELVEVKDEDKVDFSIITELNVK-HYSIKDLITLMIITSDNTATNILIDIL-GY +GNINKMAEDLKLEGTVLRRKMMDFEAA-KQGKQNVTTAWDMAVMMEALYKGTILDESMCQ +VALDILKRQQH-KDLLTRYIADDIVVANKTGDLQN-LNHDIGIFYHPYTD-YLLGVFVTD +AE-SNIGAKHIIGKVSKTVYDYf +>[subseq from] serine hydrolase n=1 Tax=Runella sp. CRIBMP TaxID=2683261 RepID=UPI001413460D +---LKKAIQAKLAGVEGNFGVAFKDLQSNQTL-FINEKENFHAASTMKTPVMIEVFKQAK +GGKFKLTDSILVKNESIVDGSAFSYKMIGKKMTIYDLTYQMIIVSSNLATNILIELV-DA +KKANATMRDFGANDIQVLRGVEDSK-AFQLGMNNSVTAYDLMVIFEKIARKKAIDPTASE +GMTRILFDQKF-NEIIPAKLPKEVKVAHKTGSIT-GVQHDSGIVFLPDGRKYVLVLLSKN +LK-DPKAGVRILADVSEMIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Melainabacteria bacterium TaxID=2052166 RepID=A0A327JBR1_9BACT +---LKKNLTNLSLAYTIEPSIFVWEYDSGKYV-DIKADKEFSAASIIKIPVLLETFKAIE +TGKLSIDDKMSLTEYYRSDGSGKLKYHQSGSYTIDELARIMIEQSDNSATNMLIAAVGGM +PEINSALKNWGIKNTHLQNWLPDMAGT------NVTTTKDLAVMLYNIENSQFISSKSKS +YIVDYMSNVEN-NRLIQAGLPQNASFIHKTGDIGK-TLGDAGIVTTASGKKYIVAIIANR +PYN-SPLGKDFIQKASSMIYN-- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas cuatrocienegasensis TaxID=543360 RepID=A0A1H9CU39_9PSED +-aELQERLERLDAESPGKLGVYVEHLSEGH-L-DYQAEGPWYLASTVKLPVAIAVLQGVD +KGRLSLDQAVELTAEDKVDGSGGTWSDVGTTFSIRTLLEEMLRESDNTAADMLIRLV-GV +DTLNASLERYGFSQTSLLQVRQDLYAELHPDARNLS------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas cuatrocienegasensis TaxID=543360 RepID=A0A1H9CU39_9PSED +------------------------------------------------------------ +--------------------------------------------------------I-GP +ERVQALANALGLTPGQLEQDLDEAYRRYYAQGRNSSSLTGYGALLRDLVRGELLSDASQQ +LLYQLTGLNQYEAYRLEAGLAEDLPFIQKTGTQQ-GRACHVGVARPETPEQALIIIACAA +DLDENREAGALFERIGEAIQ--- +>[subseq from] serine hydrolase n=1 Tax=Chthonomonas calidirosea TaxID=454171 RepID=UPI0006DD4A43 +-----ADVAAIEKASTGVLCFAAEDLQTRKVV-QHNAEHKCRTASVIKLPILVHVGLEVT +EGRRAWEEPLVLTDKEKVPGSGILSQLTAGLLTLRDVCVLMIVLSDNTATNMIIEHIGGV +NPINARMRALGLETTTCFRKVYARDALPNPYGLGVTTPREMLQLLEMIATGSLGSEALCE +EFLAILSKQHY-RDCIPRYLPEEWRYAGKTGSIDE-ARNDVGIVTDAVGNRFALALFCQE +LQ--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Caulobacter sp. Root1455 TaxID=1736465 RepID=A0A0Q7SXT2_9CAUL +-qKMTADFQPIADRVPGQLGVAVEDLGTGQII-SFNGERRFPLQAVFTAPLGAAVMAEVE +AKRLRLDDILLIEDVDLSPPSGVADLWAGPMYSVQDLLERAIRDGDNTAADVLMKRIGGP +GAVTAWLQGRKVNALDIDRYQRQLQPAYLADPRDTATPLGALRFLEAVNQAELLGPDSRR +LLGRIISQTRGGAGRLRAAVPEGGRLNHIPATARTDVVNDIGVYTLKDGRKFAVVAFISG +SPLPVAEQEKAIADVGRVVIK-- +>[subseq from] serine hydrolase n=1 Tax=Aquisphaera sp. JC669 TaxID=2712864 RepID=UPI0013EAFDE8 +--TLAGRLDPLIRAYKGKVAIAVKNLKTGEEF-HHRGGEVMPTASLIKFPVMVEAYRQAS +QGKIDLDARVALRVEDKVPGSGVLTDHFSAGIALKDAVRLMIMFSDNTATNLVLDAI-GI +GATAATMESLGYPNTKIHSKVFRRDTRSKKYGLGSTTADEMVRLCQALHEHRLVSPAASD +RMLEHLRTCDD-RDKFPRGLPYGTKLAFKTGSVDD-ARTCAGLIECPGGT-VAVCVLTCE +NEVPDNAGNLLCAEVARAVFDHf +>[subseq from] serine hydrolase n=1 Tax=Desulfosporosinus sp. FKA TaxID=1969834 RepID=UPI001124DE33 +-dKLARDIKKIIQNERGSYSISYQDTISNNNL-VINP-QKMTAASMIKLFVMIESYNQIK +EGVINENEKITLTSSMKVGGTGSLSSRKDGTLTIDQLIYLMITQSDNTATNILIDRI-TM +DKINTTVQKLGCLDTVLQRKMMDFKAQ-GEGKENYTSAADLCNILTKLYKNECLGEKYDP +KMIEILKRQEN-NTKLPLLLPAGTVVAHKTGELDQ-VENDAGIIFTPKGA-YVLCVLSSG +IVA--GDARTIIAKVSKVVYN-- +>[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=A0A2T2WJP0_SULTH +------ELQNLIQTLPGRYAVFAKNLETQKTF-AYHEHDIFPSASVIKVPILIELYRRVE +EDHLSLDHLLLMRKEDQVGGSGVLKDLTPGTYSLRDLATLMITVSDNTATNLLIDYL-GV +DWVNSTIRRLGTQNTELIRKLQRVPAE--YDQINHTCAYDMALLMEKLATGTAISLAVSE +QMVNLLTRCQG-PVSIAKISAKEVIIAHKTGSLSE-ASHDVGIVYSPHMN-YVAAILSEG +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Cyclobacterium jeungdonense TaxID=708087 RepID=UPI0013D21E15 +-eTLEKDILSLMQATEGDFGIAFRMLDSGSQL-LINEKEVFHAASTMKTPVMIELFKQAE +EGKFDLQDSILIVNESIVDGSTFSYEMIGEKTTIYELMYQMIIKSSNLATNILIDLV-GA +DNVTQTMRDLGAEDIEVLRGVEDLKA-FDAGLSNTTTALDMMLIMEAIALGKV---EGSE +EMVTILSDQYF-KDLIPKLLPEDVKIAHKTGSIT-GVQHDAAILELPEGKRYVLVILSKN +LV-DVAAGKETIARISRLVFEY- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. BL4 TaxID=2478710 RepID=A0A3L7B7Y8_9ACTN +------------------SGVTVRDLSGDQQI-AVNGALRPKAASVIKLWILVELLRRVD +CGQVSLDDRVLVTPADVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNIAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILSPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSE-TAVAFLTAG +PM---ETGDETVRRMARTVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Siphonobacter curvatus TaxID=2094562 RepID=A0A2S7IGL9_9BACT +--SLKEQIQHYLSGRKGTYAVAYKNLATGDHV-YINENDSFHAASTMKTPVMLEVYRQAY +KGKFSVLDSIVVKNESIVDGSPYSYEKVGQKRTIYDLMYEMIIYSSNLATNIIIDLV-DA +RNVTKTLCKMGAKHTQVLRGVEDKK-AFAQGLNNKVSAYDLALLFEKIAKGKAVSPEASQ +AMISILLDQKF-NSVIPAKLPKSVKVAHKTGSIVS-IMHDSGIVYLPDGRKYVLVLLSKN +WQPDREAAVETMATVSEMIYQ-- +>[subseq from] D-alanyl-D-alanine carboxypeptidase n=1 Tax=Planctomycetes bacterium Pla108 TaxID=2528001 RepID=A0A5C6A2J8_9BACT +-eALDKALGPMLKGHQGVVTVAIKHLETGDSF-AYDAERPMPSASMIKLPIMLTAYHAAL +EGKLSLDDQVVLKEEDKVPGSGLLTENFTAGLTLRDAIRLMIGWSDNTATNLVIEAIGGI +HAVNKLMKALDYENTRLNSLVFRGDTTIDPERSGVMNAADTIDLLEKILTDKEKVESMRK +EMMGHLRACQA-KNTLPRMLPAGTVVAHKGGSVT-ASRCDGGVIESPTG-PIIVCVMTTD +NEDADAEPMTLIAEVGKAAYDYf +>[subseq from] D-alanyl-D-alanine carboxypeptidase n=1 Tax=Planctomycetes bacterium Pla108 TaxID=2528001 RepID=A0A5C6A2J8_9BACT +---------------------AIADGETGEVLwGFNEDGTRDPASTTKMMTAYVVVKLAE +KDPSVLDEVITFSERADKTSGSTSDVNAGEQVSVRELLYGLMLPSGNDASVAFAEHFGGE +SPYDRFIAEMNATAKDLGMDETGYRNHGLTAEGHVTSARDLVKLAHAAMQNELF------ +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Rhodocytophaga sp. 172606-1 TaxID=2704465 RepID=A0A6C0GIK0_9BACT +--AIQQQIQHELNSIPGTFALAFINPDNPKQQlLINAKEVFHAASTMKTPVMIEVYRQSS +QGKFSLQDSILVKNESIVDGSLYSYKMIGKTMTIEALVYDMITYSSNLATNILIDKV-GA +KNVMITMKALGANDIQVLRGVEDSK-AYQQGLNNTTTAYDLMLIFQKMALHQLVNAEVDQ +AMINVLLEQKF-NEIIPAALPKSVKVAHKTGSIT-GVQHDTGIVYLPDGRKYVLVLLSKN +LQ-DSKQGIAILSKVSGIIYRY- +>[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus halophilus TaxID=226505 RepID=A0A1N6G5X6_9BACT +---LRENVLAQLDSIQGDVAVAYINLADPSDTlMIRASEEFHAASTMKVPVMIELYKQQE +EGKLDLSDSIVLVNESIVDGSPYSYSKIGTTVSINDLTYSMITVSSNLATNVLIELV-DA +KNVTATMRTLGADKIEVLRGVEDQK-AYDLGLSNSTTANDLMMIMKAIAEDQAGTPADCE +EMISILKDQQF-NEIIPFYLPKDVTVAHKTGSIT-GVHHDAGIVYLPDGRSYVLVLLSKN +LE-DFDKGTNQLAKVSKLIYDHf +>[subseq from] Serine hydrolase n=1 Tax=candidate division KSB1 bacterium TaxID=2172550 RepID=A0A6A0I1D1_9BACT +heKTEAKLWEIAGNVSGVMGIAALDLTSGERF-GVNENMIFPQGSAIKIPVLMEVYKQAT +EGKFRLMDLRWIDKEHKVGGSGILQQLGDHTLSIRDLAILMIVLSDNTATNMLIDLV-GM +ENVNRTMSSLGLTQTRLQRRMINAAAS-GKGEENLSTPFEAVRIMEILHRGEFLNRQVCD +EILEILKKPKSG--GLNAGLPANLPAAFKPGGIP-GVSTEWAIVYLKER-PYAVAVMEKY +EM--NGEAKSAMKEISRILYDYf +>[subseq from] Serine hydrolase n=1 Tax=candidate division KSB1 bacterium TaxID=2172550 RepID=A0A3A0C506_9BACT +------------------MGVAFRDLETGQEY-FFNEKSMMHAASTMKVPVMIEVFRQVE +AGKFRLEDSVFVRNQSIVDGSPYSYKVIGQKMSVHDLVYQMITVSSNLATNLLIELV-DA +KKVMATLQQLGIHDMQVLRGVEDGK-AYQLGRNNRTNALDLMLCLQAIAEQRAAGPASCQ +TMIAILKDQKF-RDSIPAGLPEGFIAANKTGSIT-AINHDAAIILHPNRKPIVLAILTRK +IT-NHEQARATIAGLTRHLF--- +>[subseq from] Beta-lactamase class A n=1 Tax=Niastella sp. CF465 TaxID=2135684 RepID=A0A4R2W0F0_9BACT +-nKLKDQIGSKLAEQPGDFAVAFKDLTTGESI-LINELTFFHAASTMKTPVMIEVYKQAA +AGTFSLNDSFTLKNESIVDSSSFSYKHLGEKRTLYSLVYDMIISSSNLATNMVIELV-NA +RNVTQTMRQLGAGKIQVLRGVEDSK-AFAKGLNNVTTANDLLVIFEKMAKGEIVDSASSQ +AMIKILLNQQF-NEIIPARLPKDVSVAHKTGNITN-VLHDSGIVLLPNGKKYVLVLLSKN +LQK-EEQAKNAMAEVSEMIYKY- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=B5WXV7_BACT4 +---LTDSISQIVSACPCEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=R7LYN1_9FUSO +---LQSELQNLAKLYTVEPSVYVWDYETQNYV-DINASKIYSTASIIKIPVLIDVFKSIE +AGQISLEDKIPLTEYYRTEGSGSLQFKARNSYTIDELARRMITESDNSATNMLMAKVGSM +TDVNQSIRDWGLKNTEVQTWLPDYAGT------NHTTAREMADMLYNIDEDKFLTEASRT +KMLDYMGHVHN-NRLIQAGISPDAVFLHKTGDIGS-MLGDAGIVIAPNGKKYIVVILANR +PH-NAIAGKDYIVHASEIIYNY- +>[subseq from] serine hydrolase n=1 Tax=Arenibacter sp. JC631 TaxID=2608629 RepID=UPI00123D2702 +-eELEKTIQAQIDSIDGTVAVAFYSLSKPKDSlLINVDEKFHAASTMKVPVMIELFKQAS +QGKINLQDSIVLKNESIVDGSLYRYNQIGSKVALKDLMHSMVTISSNLATNVLIELV-DA +KKVTASMRDLGAENIEVLRGVEDLK-AYEKGLSNSTTAKDLMVIMKSIANNSAGTPKDCE +AMITILKDQQH-KSLIPFYLPEEVKVAHKTGSIT-GVHHDAGIVYLPDGNAYVLVLLSKN +LK-DIDKGTEQLARISKTLYDY- +>[subseq from] Beta-lactamase n=1 Tax=Photobacterium damsela subsp. piscicida TaxID=38294 RepID=A0A1V1VGR3_PHODP +--ALVNIIKQQEKALNGTIGIAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD +KDKLALTHQVVIKKSDLVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP +EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDPRDTTA----------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A2Z6A9I9_SHIFL +-------------------------------------------------MALAAVLKQSV +TQKQQLNEPDEIKPADMVNYIPIAEKHVNGTKTLAELSAAALQYSNNTAMNKLIAELPGP +GGVTTFARAIGHETFRLERTKPTLITAIPPDPRDTRTPRAKAQTLRQLTRGHTLGETQRP +QLVTWLKGNTTGAASIRAGLPTSWTVGDMTGSGAYGTTNH-------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Gynurincola endophyticus TaxID=2479004 RepID=UPI000F8EC8CE +-----SSIQQILDTAQGQFAVAYKNLTTGETV-FFNEDSVFHAASTMKTPIMVELYRNVS +DGKFTMNDSVLIKNESIVDGSIYQYQRVGTSTTLYELTKEMIITSSNLATNILIEWV-KP +EAIKQTLAAAGIEDVKVLRGVEDGK-AYRAGLNNTTTARGMMLFFEALYENKFTTEAYTK +EMIDILGEQKF-NEIIPAHLPDNVKVIHKTGSIT-GVVHDAGVVILPDGTSYCLVLLSKK +LE-DSEKGKATLANISKILYEH- +>[subseq from] serine hydrolase n=1 Tax=Pseudorhodoferax soli TaxID=545864 RepID=UPI000DF32A90 +------------------------------------------------------------ +-----------------------------------------------------------P +QRAEAVRRALALPAGALRTDIDTAYADYYAEGHNSATLAGYGAMLERLVRGELLSPASTD +RLFKAMKFGTRGSYRLEAGLPKSLPLIHKTGTQHR-RACHVGVVQPQDGDATVLAVCAAD +LD-EQRAAGRLFEAVGRAIA--- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. BL4 TaxID=2478710 RepID=UPI0011C3E7D4 +------------------SGVTVRDLSGDQQI-AVNGALRPKAASVIKLWILVELLRRVD +CGQVSLDDRVLVTPADVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNIAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILSPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSE-TAVAFLTAG +PM---ETGDETVRRMARTVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. 15K316 TaxID=2530376 RepID=A0A4R4QQU4_9ACTN +-----GQLQQVVDASTANAGVAVRDLSGDQQI-AVNGAFRPKAASVIKLWILVELLRRVD +CGQVSLDKGVLVTPAQVVDGTGELQHETFPQVTLYRLAEYMIKYSDNTAANVLIDYFGGF +APVNDLTDSMNQRETILARKMLDTEAA-MRGEENYTSPDDVVALLGAVWDAQILTPATRD +LMIGFMAEQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSQ-VAVAFLTSG +PM---AGGDETVRRLARTVYDY- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Bacteroides pyogenes TaxID=310300 RepID=UPI0011E40F60 +---LTDSISQIVSACPGEIGVAVI-INNTDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NREVSLGTLVNINRDKLDPWSPMMKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYANYTSPLGAAMLMNRLFTESIISDEKQN +FIKNALKECKTGTDRIVAPLKEGVIIAHKTGSGYNGAHNDVAYICLPDNVCYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3A0ADJ0_9CHLR +--NLTKQLTEIIAASGATMGVALHHIESGEEI-NLNADESFPMCSVLKIPVLVEAFRQLR +QGKFTLEDRWELTTAEKNIGSGILTYMQDGLPTVRDLLTLMIIISDNTATDIVMHRL-GV +EQIDRTMHELGLADIHMALTIRGIFDFSSGPDNNVSTPRDMTRLLAMIFRGEIIDRAACD +EMLYILLQQQL-NARLPLFLPYGIPFAHKTGTLA-GIRNDAGILYCSDESHVAITVFARW +DTEAVKDD--------------- +>[subseq from] Serine hydrolase n=1 Tax=Niabella ginsenosidivorans TaxID=1176587 RepID=A0A1A9I484_9BACT +-qAVNQQIRDSISRSGASIAVAFKDLQTGNTL-YINEKKTYHAASTMKFPVLIELYKQAA +ENRYSLTDSLVLNNSSIADSSRYSYRKLGRKIAIKDLAYLMITKSSNLATNTLIQLV-RP +AGIMQTLRQLGANDTRVLRGVEDQK-AYDKGLNNTTTAFDLALLYEQLAKKELVSEKADQ +SMIKILMDQQL-NEVIPALLPENVKVAHKTGNIE-GLQHDSGIVFLPDGRKYVLVLLSTF +RPDQTRDAISTLAHISKLIYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Larkinella sp. BK230 TaxID=2512173 RepID=A0A4R8CXP5_9BACT +------HLTTYLKKLTAQVSVAVEELAGKTTF-YHRADDLPPAASVIKLPIMVETMEQVK +AGQFDLDKIHLLQDAEKTGGSGILQTYPAQSLTNREVLTLMMTHSDNTATNILIREL-GM +DKINQRMRSLGLMQSVLNRLMLDTLAVKQG--------REMNALLKKIYRREVATPALCD +QMIEILKGNRD-QKTFRMFLPPSTVIAHKTGELTY-VRGDVGIFYVT--KPFLLSVFVQG +VS--TQEAERMIGEIAQLCYNQf +>[subseq from] serine hydrolase n=1 Tax=Mycobacterium paragordonae TaxID=1389713 RepID=UPI00105E5EBB +----ERQVERRILAAPADVAVFFRLLGGEAEW-SYQPDVTFHAASTMKVPVMIELFHQAH +QGQLTLDDPLPIHNESLVDGSAFYYSSEGQTRTLRQLCELMITMSSNLATNLLIKKL-GI +ENIRATVHLLGADGMNVLRGVED-NKAYDLGLNNTTTARALAILLTAIAEGKVVDPDASR +QMVEILKRQHI-NDSIPSGLDPTIPVAHKTGTLK-AIHHDAAIVYGP--QPFVLVILVRG +MAN-SKDSSALMADITRAFYR-- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas argentinensis TaxID=289370 RepID=UPI0008A985F6 +---LLERLQAIAAKQNGELGVYVKDLHSNLAV-TLQAERLWYMASGIKVPVAIAVLRGVE +RGDWGLDTRLALVANDFVDGAGSTNQYGPGELSVRFLLEQMIIYSDNTATDRLIRLV-GL +DALNGLVRELVPEGFEPITTLGDVRRAYYRSNLNAATLSAYGELLERLATGQALGNEQTA +YLLEVMGRVKTGTQRLIAGLPEDARLAHKTGTQR-ARICDSGLIQTPEREPVLIVACVEG +E-PSLAKAERALRQVGEALT--- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Desulfosporosinus acididurans TaxID=476652 RepID=A0A0J1FKW2_9FIRM +-dKLTRDIKKIIQNERGSYSISYQDTISNNNL-VINP-QKMTAASMIKLFVMIESYNQIN +EGVINENEEITLTSSMKVGGTGSLSSRKDGTLTIDQLIYLMITQSDNTATNILIDRI-TM +DKINTTVQKLGCLDTVLQRKMMDFKAQ-GEGKENYTSAADLCNILTKLYKNECLGEKYDP +MMIEILKRQEN-NTKIPLLLPAGTVVAHKTGELDK-VENDAGIIFTPKGA-YVLCVLSSG +IVA--GDARTIIAKVSKVVYN-- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus sp. CHY01 TaxID=1844116 RepID=UPI0011163515 +-kALEDQIFRIIDQAGGAWGVVIEDLHTKEKI-EHQPDVRFFAASLIKVPIMTAVFADVY +AGKYAFEDRLSLRQEDLVGGAGVLQHLQPGLLSIYDLVMLMIIQSDNTATNILIDQA-GR +DSIRAIMDKTGMVNSQFYNKLMIIPAELEG--RNEVTAGDMASILRHLAHGSVISYDSCL +RMIDILKRQQL-RDALPLLLGPKWELANKTGTVT-GIEHDTGILYTGQSA-VLISVLTKD +AT-DSLTAKRAIGEIGKLVYEAy +>[subseq from] Beta-lactamase n=1 Tax=Archangium gephyra TaxID=48 RepID=A0A0G2ZQW0_9DELT +----RASLQEIAQVKGATVAVAYQHLGNPRDSlFLEADRSFHAASTMKVPVMIEFFRQAD +AGKLSVGQELTLANQSIVDGSPYAYERLGKPVPARELVERMITRSSNLATNTVIALV-DA +KRVTKTLRSLGARQMTVLRGVEDGK-AYQKGLNNSATARDLATLMTAIEQGKAASPASTQ +AMRSILLAQEL-NLEIPAGLPPGTPVAHKTGQIS-GVLHDAAIVYPSGRPPYVLVVLTSG +IP-DEKVARSLIADLSRQVFA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora krabiensis TaxID=307121 RepID=A0A1C3N577_9ACTN +-------LSQVVDASTANAGVAVRDLSGDQQI-SVNSTFRPKAASVIKLWILVELLRRVD +CGQVSLDDGVLVTPAQVVDGTGELQHETFPQVTLYRLARYMIKYSDNTAANVLIDYFGGF +APVNDLIDSMNQRETILARKMLDTEAA-MRGEENYTSPDDVVALLGAVWDAQILTPATRD +LMIGFMAEQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGA-QVAVAFLTSG +PI---ATGDETVRRLARTVYDY- +>[subseq from] Putative Extended-spectrum beta-lactamase PER-1 n=1 Tax=Candidatus Sulfopaludibacter sp. SbA4 TaxID=2043165 RepID=A0A2U3K768_9BACT +-kRLESNIQRVTQSVNATWGIYIKCLETGEEI-ALNADQQMDTMSVIKIPLMAEAFRQME +AGKFALTDRIALTDAAKQPGTGIIRSLDAGVLTIKDLLTLMIIVSDNTATDLIYDKVGGP +EPVNKLMAEWGLNSIHATGKADAWFKRAGKTPFGLSSPRDMGKLLEKIEKGEAVNQKSSD +LMLQMMRGQVY-SSRLPRYVS-GFRIPHKTGDFLPYIGNDVGVLESPSR-RIVMSVFTAN +HFGAGDRLEDAIGRIAELTGNYf +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium MalM25 TaxID=2527998 RepID=A0A517TJT3_9BACT +--ALAAALGPMLESHQGEVTVAVKHLKTGRTY-LHNADKPMSSASLIKAPVMLTAYRLAA +LGQLSLDDPVTLREEDKVPGSGLLTPHFSNGVPLRDVIHLMIAWSDNTATNLAIEAIGGI +AETNDLMEKLGYENIRLNSLVYRGDTTIAPDRSGLMSAAETLDLFEKLAKGDAVVEAYRA +EMLDHLRACQY-NDMVPRYLPKGTVVAHKTGGVSN-ARCDAGLIESPTG-LIAYCVMTDE +NAEEDAAPHVLIAQIGKAAYDYf +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium MalM25 TaxID=2527998 RepID=A0A517TJT3_9BACT +-----------------------------------------DPASTTKIMTAHLVCRLAQ +QDAKVLDEVVTFSERADKTSGSTADLREGEQVSAGELLYGLMLPSGNDASVAFAEHFGGD +TPYDRFIAAMNAEARRLGMNETGYRNTGLTAEGHVTSARDLVKLAHAAMQDGTFREVVAT +RRYATTVSSTTGYQRTDQLLKREGFYGVKTGTTGPAGACLVSAGER-DGKPLYVVVLGAN +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium QS_3_64_15 TaxID=1919105 RepID=A0A2T2U1Z5_9BACT +--TLEEDVRAVLDTVEGDFAVAFRSLDTSQTL-LINEHQTFHAASTMKTPVMIELYRQAK +GGRFDLDDSIRVENESIVDGSTYSYEHLGEQRSIRTLMREMITASSNLATNILIEKV-GA +ERTTQTMRRYGADRIQVRRGVEDMR-AYRRGLNNETSAHDLMVIFERLARGEAVSEEASQ +EMIQILKGQEY-DDMIPARLPDAVEVAHKTGWIT-GLHHDPGIVFVPDGPTYVLVLLSQN +LE-DEDAGVTAFARISRLVFD-- +>[subseq from] Uncharacterized protein n=3 Tax=Bacteria TaxID=2 RepID=A0A1J4VCV4_9BACT +---------TIAQKRGVRIGFVIKDLKTGRTL-LRNENARFASASLVKIPLLITLYRDIT +DGKIKVLQGAYYSEKLRASGSGRLKSEPANRINLRDLVFLMLQHSDNTATNILADLV-GY +DHVTRYCRTMGWRNTNFVRPVMALELR-AKGIENWTTPKEFSEIIEKIFRGSMISQEASR +EMIQFMTNPPI-DDRLPRYLPPRIDIVHKTGLIYD-NAHDVGIIYLPGDQAVLVSAFADN +IGTNYMTAKETIASIARIIYE-- +>[subseq from] Serine hydrolase n=1 Tax=Niastella vici TaxID=1703345 RepID=A0A1V9FYS2_9BACT +-nKLQDNIKSKLAEQPGDFAVAFKDLSTGETI-LINEQQYFHAASTMKTPVMIEVYKQAA +AGAFSLNDSFVLKNESIVDSSVFSYQHLGEKRSLYNLVYEMIIRSSNLATNMVIELV-NA +RQVTQTMRQLGASHIQVLRGVEDSK-AFDKGFNNVTTAGDLQVIFEKMATGEIVDSASSQ +AMINILLNQQF-NEIIPARLPSTVKVAHKTGNIMH-VQHDSGIVFLPDGRKYVLVLLSKN +LQK-EDQAIKAMAEVSEMIYKY- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Cryosericum odellii TaxID=2290917 RepID=A0A398DEV0_9BACT +----------LEYSQRVDVGIGFKDLKDGTEI-FYNGEKEFPLASVFKIPVLMTLYKQQE +LGILSIDDYYTIEEKDITRGSGVIKELKPGVMTLRDIAILMMIISDNNATDIIIKLV-GK +ENIKKTLEAIGVTNTIASVTTKDLKKPLNVKESNYSTPRDMIKILESIYKNTYLTRESCD +GILDIMKKCQTGLNRIKKYLPFGVKIAHKTGSLSINVVNDSGIIFTRQKD-YVLSVFVTQ +YNTEV------------------ +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium 40-81 TaxID=1895835 RepID=A0A1M3QU06_9SPHI +--TLRKKISDIFSQFGATFGIAFKNLNTSATF-FWNAEDIFHSASTMKTPVMIEVYKQAA +QGKFSVTDSMLVKNSSIVDGSTYSYLHIGKKLPIRDIVFRMITVSSNLATNNIIELV-GA +KNVTATMRSLGTKNMLVLRGVEDKK-AFEQGLNNITTAYDLMLVMESIAKGTVADKKSTD +DMIDILLHQRF-KRVIGGKLPAGVKVANKTGAFK-GVRHDSGIVFLPDGRKYVIVLLSRG +IE-DEEKSAAALAEVSRLVYE-- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella intermedia TaxID=28131 RepID=Q8KT53_PREIN +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRWFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3QWR2_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +QRVTALQRVLNVPASALTRDFDEAYARYYRHDNNSATLEGYGAMLEKLVRGELLKPASLQ +RLNDGMKLGIYTNYRLQAGLPRGVDFIHKTGTQHR-RACHAGVIRPKDGAQGIVVVACTA +DLDEQKAAGPVLQRVGQAVTQ-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535JH70_9CHLR +------VVARILQTTARGVGVYYRDLTTGDSL-TVGSDGRFHAASTMKIPVMIQLFRDRD +AGLLSLDDSIIVTNTSLVDSSPYQYKRLGQRASIRELIELMETVSSNLATNLLIAKV-DA +KRANATAHALGADSILVLRGVEDGK-AYRAGLNNTTTARDLGMLLAAIANGTAASAGSCR +DMLAILGRQHF-NEGIPAGLPAGTRIYHKTGWIGQVVYHDAAFVQPQGGRGYVLVVLTGG +IQKD-DDAHALARDVSKLVFDAw +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A359KKG3_9CHLR +----EELVTTIEQASGGTVGIAVAG-PDGNRW-SHNGQRQFKAASTVKIPLMIEIYRQID +RGERSLDERHVLSAIEKAAGSGVLLHHDGIELTIDDLIYLMISISDNTATNMLIDLA-GM +DAVNATMLELGMSMSTLARKMKGRP-AIEGEQENLATPDDYVAIVDAIFGDRATSTAARE +AMVTMLSRQQN-ARRIARYLPADLRWGSKTGSIA-GVTNDVGFVETPVGR-MILAVFCEG +FP-DQHDGEYAIGELSRAALH-- +>[subseq from] Uncharacterized protein n=3 Tax=Erythrobacter sp. QSSC1-22B TaxID=1860125 RepID=A0A1A7QE17_9SPHN +------------------------------------------MASTFKIALAMCILQLID +HEKVALDQMVEISADLLVPPPLIEPRHIGLAISVANLLDIMMVTSDNSATDALLKLVGGP +DYVSQAIAKANIAGMRIDRSTSQFLANYDDDERDNASPAAMAKLLAKLWHGNLTSIASRD +RLFEVMERCEN-DNRIKGCMPAHVTIAHKTGTLG-GSTSDVGVIELPEKGSVAIAIYIKK +SASPVIIRERAIAHASRAVYD-- +>[subseq from] serine hydrolase n=1 Tax=Tissierella sp. DSM 105185 TaxID=2607614 RepID=UPI0012B1E36D +-----------INNIDEDISIVIKDLTKNQWIlKYNERDVFPSASLIKIPIMVEMFYAIQ +NGEYKLEEKINIQENSRVPYSIISELKLS-EYPLIDLITLMIILSDNTATNVLIDLL-GY +DRINESIKRLDCNDTVLRRKMMDFQGARE-GRENMTSPMDMAIIMEKIYRKSIVDIESCN +IMMDILARQKY-RDMLPRYILDEVTIAHKTGELS-GLNHDIGIFQLENI-HYLIGIFTRN +GK-DDLEGKRSIGRISKLVYNY- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI001302476B +------------------------------------------------------------ +-------------------------KYVGKDITLKELIEASMKYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] serine hydrolase n=1 Tax=Rufibacter roseus TaxID=1567108 RepID=UPI00082EBE37 +---LREQITTELNKEAGTFAVAFKDLQTGQEL-LINEHETFHAASTMKTPVLIEAYKQAA +EGVFSLQDSILLKNESIVDGSAYTYANLGKKWPLADVLYKMIIHSSNLGTNLVIEKL-DA +KKVTQTMRDLGAKDIQVLRGVEDGK-AYEQGLNNTTTAYDLMLIFEKIAKGEAANAKASE +EMVKILLDQKH-KNIIPANLPKEVKVAHKTGWIT-GVRHDSGIVFLPDGRKYVLVLLSKG +LK-DDKAGISAMANVSEIIYQ-- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6L6N5_9BACT +---LNEELERLNDQSKARIAVAVHDLESGWRF-SLRADRWFLAASTIKVALLLAVFRAAD +ESRLRLDDSLHVRNRFFSAGSPFHYQAIGRTAKISALAQGMISASSNLATNLLLDLV-GV +EYARKVLRDAQVDGVELRRGVEDH-AAHERGINNEVTADGLVRLLSAV-RGDFLSKESKE +QAIRILLEQRF-KSMIPAGLPAHATVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +AS-EQDGRRETVAAISEAIYR-- +>[subseq from] Serine hydrolase n=1 Tax=Mycobacterium paragordonae TaxID=1389713 RepID=A0A4R5WX81_9MYCO +----ERQVERRILAAPADVAVFFRLLGGESEW-SYQPDDTFHAASTMKVPVMIELFHQAH +QGQLTLDDPLPIHNESLVDGSAFYYSSEGQTRTLRQLCELMITMSSNLATNLLIKKL-GI +ENIRATVHLLGADGMNVLRGVED-NKAYDLGLNNTTTARALAILLTAIAAGKVVDPDASR +QMVEILKRQHI-NDGIPSGLDRTIPVAHKTGTLK-AIHHDAAIVYGP--QPFVLVILVRG +MAN-SKDSSALMADITRAFYR-- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000D0AE8CF +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDTYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] Beta-lactamase (Penicillinase) n=3 Tax=Xenorhabdus bovienii TaxID=40576 RepID=A0A077MT10_XENBV +------------------------------------------------------------ +-------------------------------------------------MNLLLGQLGGA +HSVTRFARSIGDNAFRLDRKEPELNMVTPGDERDTTTPQAMADSLYKLALGNTLAATQRT +QLVEWLKGNTTGGTSIRAGVPDNWIVGDKTGRCNYGSTNDIAVIWPDDKAPLILVTYFTQ +PSKDAKAHNDVLAATARIMTQ-- +>[subseq from] Serine hydrolase (Fragment) n=16 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A6B5GLX8_STAAU +---HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIA---------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Rudanella sp. HX-22-17 TaxID=2614655 RepID=UPI001262410E +---------------SVRVSVALETLADSSVRlYHRADERVPAASLIKVPIMVEAMVAEI +EGRINLDEIHILLDSEKVGGSGVLKDYPNRSISYRDLVRLMITSSDNTATNILIGDL-SP +EAINARMRALGLPQTGLNRVMMDTLAA-RQGRENVVTAREMNHLLIQIYRHRVATPALCE +QMLDFLKANED-TLTIPSRLPRQLVVAHKTGTLSY-VRADMGIVYGP--RPFVLSVLVEG +AD-SEAAGEAIIAQIARLAYS-- +>[subseq from] Serine hydrolase n=1 Tax=Planctomycetales bacterium 71-10 TaxID=1895807 RepID=A0A1U7GQB6_9BACT +--ELAAKLDELAKAHKGKVAIALKNLKTGESY-ALNAETPMPTASLIKFPVMIEAYRQAA +EGKVDLNAPITLRKKDMVPGSGVLTYHFSDGFPLVDAVHLMITYSDNTATNLVLDAI-GI +GSTAATMEKMGYPNTKIHSKVYRRDTRSKVYGLGSTTAADMVKLMDDLHAKKLVDEKASE +AMYKHLLTCDD-KDKFPRLLPPGAKVAFKTGSVDE-SRTCAGVIETKGG-PVALCVLTTD +NEDQENAGNVLCAKAAKEVYDTf +>[subseq from] Serine hydrolase n=1 Tax=Rhodoferax koreense TaxID=1842727 RepID=A0A1P8JQ86_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +KRFDTLVRTMGVDKAAVRKTIDEAYARYYAKGANTATLEGYGGMLEQLVRGKLLSAEHMK +LLYTDLKFDTYDAYRLEAGLPRTVKFIHKTGTQMH-RACHMGVIDPQDGGRAAIVVATCA +EGDEHAEAGRAFEQIGRAITQ-- +>[subseq from] Class A beta-lactamase n=2 Tax=Bacteroidales TaxID=171549 RepID=A0A4Q0J4G6_9BACT +--ELESRIGRYIADKDARIGVAVI-IDGCDTA-EVNGSQFFPMLSVYKFPQALAVAEHCR +RHGVGLPDTVRVSADEMKSWSPMRDRFGAVNLPLLALLEYSLQQSDNNACDVLFRMIGGP +AVADSLMNKWGYGDIRIRSTEDEMHRDTDLCLVNCCTPLEMARLLDDFNTGIRLRSEENR +AIASLMESCVTGRDRLARPLTTPAILGHKTGTGDVDAVNDAGYVNLPDGHRYAVAVFMAS +SAYGLEDTSRMIADISEIVYS-- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A357N964_9FIRM +---LRKKVADVLSAYTGRWGIVIANAATGDRL-ELNPDMIFPAASMIKVPIMYEIMRQAA +AGKLSLDAALRINDEDKVGGAGILKELQAGKFTVRELVTLMIILSDNMATNMLIDLI-GT +ETVNQTAAELGLKSTVLRRRMMDFAAA-RAGKENQTSAADMALIFAKIHTSAGLPRAYGE +LMLDILGRQQI-QDKLPFYLPGGITLAHKTGTL--------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7WDH3_9BACT +---------KIRKEHGETLGISFYDAQTTIQW-SFNADHYFHAASTMKLAVLLAVFRQIE +RGELTLDAPVHVRNRSIVNQEPFMYGHLGKTLAVRELAYWMITKSSNLATNLLVDVV-GI +ATIQHALDEMEIDGVKVLRGVEDQ-AAFDAGLNNEVTANGLLKLLRLVAEGKAYSKQSSE +EMLNIMLEQQY-RSGIPAGLPKAARVAHKTGNIST-VHHDAGIVFLEDRKPYVLVILTQF +GAE--TARGTAVAEVSRDIYN-- +>[subseq from] serine hydrolase n=1 Tax=Arenibacter certesii TaxID=228955 RepID=UPI00041B7E6F +-eRLKKTIKTQIDTIDGTVAIAFYSLSEPKDSlYINVDEKFHAASTMKVPVMIELFKQAN +EGKINLNDSIVLKNESIVDGSLYSYQQIDTKVALKDLMHSMITISSNLATNVLIELV-DA +KKVTATMRELGAEKIEVLRGVEDLK-AYEKGLSNSTTARDLMIIMKSIANTNAGNQKDCE +AMIAILKDQQH-KNVIPFYLPKEVKVAHKTGSIT-GVHHDAGIVYLPDGRSYVLVLLSKN +LK-DFDKGTVQLAKISKTVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea turkmeniaca TaxID=103838 RepID=A0A5S4FJ25_9ACTN +-------FETLFRMAGVTGWLYAADLDSGREV-GHGADEQLPTASMFKVPLLVEFCRQAD +AGLLDPTSRVTVTAGDRVPPTGISAMLDDVTISLRDLAYLMIAVSDNSAADVLLARV-GM +DAVNAMLARYGLGSTRVSQSCRELNESLDPARANRSTPREMARLFGLIWRDEAASVASCA +WMRTVLNMQVW-PHRLASGFPDDVAVSGKTGTLPT-LRTESGVVEYPDGRRYAVAVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Runella sp. YX9 TaxID=2282308 RepID=A0A369I995_9BACT +-eRLKEAIQAKLAGVEGNFAVVFKDLQSNQTL-FINEKENFHAASTMKTPVMIEVFKQAK +GGKFRLTDSILVKNESIVDGSAFSYKMIGKKMTIYDLTYQMIIVSSNLATNILIDLV-DA +KKANATMRDFGANDIQVLRGVEDSK-AFQLGMNNSVTAYDLMVIFEKIARKKAIDPTSSE +GMTRILFDQKF-NEIIPAKLPKEVKVAHKTGSIT-GVQHDSGIVFLPDGRKYVLVLLSKN +LK-DPKAGVRILADVSEMIYD-- +>[subseq from] Uncharacterized protein n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A644V629_9ZZZZ +-------LNNVIAQSGAACSVYYKSLTTDQVF--YNYSGKMPAASLIKVFILAEAMDEVK +AGNYKLEDEYKIDVSDIVEGSPALQNRQAGTISFGTLLEKMITVNDNTATNMLIDIL-GM +DTINEYIQAKGYEDTVLSRKMMEVEAQ-KAGKENYTSVNDLVNIFERLYNNKCVSAEYDK +KMLQLLKQQKA-NNKIPALLPKNITIAHTDGDLP-GVQNDCGIVYAKEN--YILAIMTDG +SI-DKGKTLKTINQISSIIYN-- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2E9NKC2_9BACT +------------------------------------------------------------ +----------DVTAADLHPGSGTLSPLLAQPLSIRNLMELMLRISDNSATDMLLARAGGS +EAVTARMRALGIDGIRVDRPTALLIAEFDLDPRDTATPNAFAELLARLHRGELVSEDSTA +LLLDIMERCLTGENRLKGLLPADTVVAHKTGSLA-GTANDVGIMALPDSGHVAIAVLMKS +SDRSGTDRARAIAEIARAAYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Aminicenantes bacterium RBG_13_59_9 TaxID=1797268 RepID=A0A1F5B2Q7_9BACT +--SLRKAIKAEIGQSGAEVSLAFKDLQTGDTL-FIREKDMVHAASTMKVPVLIEVFKQAE +EGKFRLDDRIVVKNESIVDGSPYSYGLIGKSLTVRELAERMITVSSNMTTNILIELV-KP +GSIMSTLELLGIRRMRVLRGVEDGK-AFEKGWNNQTDAFDLLKVMESIASGRAGSRASCR +EMTLILEKQKF-RGGIPAGLPPGIGIANKTGSIS-GMEHDAAIVFPPGRKPYVLVVLTRG +IK-SSEEGEKLISRLSRLIY--- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. mrc49 TaxID=2054913 RepID=A0A2M9NNM1_9BACI +---IENDILALVDAFDGNIAYKIES-GFGDMI-GYQEEDSFQSASLIKIPMIIEGYRQSE +RKNIYLNQPVTIPPNAVTGGSGVLHALSNKVLTVEDLLTLMIMVSDNTATNMMMSLL-GF +DEINRCIQELGLKNTILGRKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE +RILRVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVSHDCAIIRSETQT-VYAAVLTEN +M-KSEEESRQVISKIGKLIYDH- +>[subseq from] Beta-lactamase n=2 Tax=Lactobacillus saniviri TaxID=931533 RepID=A0A0R2MTU5_9LACO +--AVRAEINRYITPLAGTNSVYVTPMNASQPL--VINNRPQRAASTIKLFILATAYAKVS +RGQFNLDQHYTLQETDKVGGTGVLGGQAAGTLSYRDLLNDMITQSDNTATNIIINLVGGM +PAVNAEIRQLGARDSQLNRKMMDTAK-LTAGVDNVTSVQDVGHLLQRLYRHQLLSADADT +QMLNILQRTQN-HSKLPASLPATATVYNKTGEFDYGVQNDAAIIADKKGA-FVAVVMCQN +GNE--AAQISAMRQLGSALY--- +>[subseq from] Uncharacterized protein n=1 Tax=Bdellovibrio bacteriovorus TaxID=959 RepID=A0A161QFR4_BDEBC +-kTFEESLKELEAKQPIQLGVFVKNLSTGEIL-SYRGDDLWYVASGVKLPIVLENLRQVD +QKKYTLDSQIELRKEDFVDGAGYTNSKKAGSLSVKFLMEQAIIYSDNTASDLLIRQA-GL +ESVNSCVQDLVPGGFTAITTLADVRRNYYSKKLNSATLKAYAELLEKVAEGKILGDSTQK +FLIDTMTKVQTGQRRIKAGLPKKYSFAHKTGTQHS-RICDFGIAWDKKSTGIVIAACVKD +FE-SLDMAESALRSVGTVL---- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=A0A412K4L1_9BACE +---LTDSISQIVSACPGEIGVAVI-INNTDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NREVSLGTLVNINRDKLDPWSPMMKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYANYTSPLGAAMLMNRLFTESIISDEKQN +FIKNALKECKTGTDRIVAPLKEGVIIAHKTGSGYNGAHNDVAYICLPDNFCYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. R2A2 TaxID=2213057 RepID=A0A2U9NHF9_9PSED +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARKLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE +GLDEGKEAGSLFEQVGRAIS--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8RTD8_KLEPN +------------------------------------------------------------ +---------------------------------------AAXYMSDNSAANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYL-- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium disporicum TaxID=84024 RepID=A0A173XE44_9CLOT +----YKTVSNILSKYDFNYSIIFKDLSSSETI-SWHYNSKFPSASTIKIFIAIEAYNQIN +KGIIFEDDVILIEDNMKVGGSGIISKYSKNLISIGKLIYLMMTESDNTATNILINIL-GM +DNINVMIKKLSINNSFLNRKMMDFN-AIKNGFDNYTCAYDLATVLEQLYKNTCINEHYDN +LILSIMTNCRN-NSKIPSRLPSKIKIAHKTGELDY-IENDAAIVFTPYGD-YILTILTEG +LD--NEKEIKIISEISKIIYDSy +>[subseq from] Beta-lactamase class A n=1 Tax=Brevibacterium celere TaxID=225845 RepID=A0A366IIY6_9MICO +----------------------VWGTHQGRTV-VHDPTTRIRMCSTMKLPLAALTLRESA +RGGLDLDTVLTWTAEDLIGHSPFTREDEDSTATIAELAEAAARGSDNTAANLLIDEVGGL +PALNAYARDLGDRVTRFDRYETEMNEL--SGELDTTTAASFAALALEA--VGQLGPDDRR +TLFSWLPGHD--DRRIGAVVPAGIDLVHKTGTSGDGVLNDVAIMHDDAEVVGGLAVFTDC +PSPS----EEVVVEIAR------ +>[subseq from] Serine hydrolase n=1 Tax=Acidovorax sp. Root219 TaxID=1736493 RepID=A0A0Q8TDC6_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +KRVDALARTIDVATTDLRKTMDEAYQRYYARGLNSAPLTSYGGMLEKLVTGKLLSPAHQQ +RLFTDLKYATYDAYRLEAGLPRSERFIHKTGTQLH-RACHMGVVNPQDGGRAAIVVATCA +EDDEHGEAGRAFEQIGRALTQTf +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas zhaodongensis TaxID=1176257 RepID=A0A3M2HYF0_9PSED +--DFLERIAKVDEQTSGELGVYLKDLDSGVSA-SYHGDEVWYLASTVKVPIAIAIMRRID +EGTMSLDTTVRLMESDYVDGAGPTNSHKPGTLSVRYLMDQMLIHSDNTASDLLISLV-GL +DAINAVTAELVPQGFGPITRLADVRRRYYATPFNSATLQAYGDLLSALIQGRAASRASTE +YLISVMNRVETGTQRIKAGLPKTVGYAHKTGTQVS-RICDAGLIAPPPAGQIVVVACVRG +G-ASTAKAERALRGTGEAIT--- +>[subseq from] serine hydrolase n=1 Tax=Bdellovibrio bacteriovorus TaxID=959 RepID=UPI0009BE8C9D +-kTFEESLKELEAKQPIQLGVFVKNLSTGEIL-SYRGDDLWYVASGVKLPIVLENLRQVD +QKKYTLDSQIELRKEDFVDGAGYTNSKKAGSLSVKFLMEQAIIYSDNTASDLLIRQA-GL +ESVNSCVQDLVPGGFTAITTLADVRRNYYSKKLNSATLKAYAELLEKVAEGKILGDSTQK +FLIDTMTKVQTGQRRIKAGLPKKYSFAHKTGTQHS-RICDFGIAWDKKSTGIVIAACVKD +FE-SLDMAESALRSVGTVL---- +>[subseq from] Serine hydrolase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520H2I8_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +QRVEAVRRALNLKPAELQRTMEQAYERYYARRLNAATLEGYGAMLEKLVRGQLLSPAGTR +RMFSDMKLGIPTNYRLQAGLPRDLPFIHKTGTQHR-TACHAGVIEPENGAEAIVVVTCAA +DVDEQKEAGRIFERVGQALT--- +>[subseq from] Class A beta-lactamase n=2 Tax=Bacteroidales TaxID=171549 RepID=A0A3N2M6K9_9BACT +--SLQNELTSFVENKDARIGIAVI-INGKDTV-SVNGSKDFPMMSVFKFPLALAVAKWVD +SNGMSLNDSIAFGPKALIKYSPMLKKYGSGLMSFKELLEWSLIESDNNAADLLLKRVGGT +ACATTLLKDAGELDITIGASEQNMHQDPYTSYLNRSTPLAMATLFDRFDTEIKNRSKSFS +DISVMLEQCRTGLDRLAAPFATNAIVGHKTGTGFISAINDCGYIHLPNGTQYTIAVFVAD +SAYDMTETSKIIADISEIVFK-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingorhabdus wooponensis TaxID=940136 RepID=A0A426RTZ8_9SPHN +-eKLTADIDSYWKKFPGRSGIAIYTPFSEEII-GKRHTERFPQQSVSKMWVALTILEQEA +SGKLSLDKRIRVSREDVVVFSQPLKNYLDGRMPLRELLAHSINASDNLANNVLLRVAGGP +QAINQMLERRKIQSIRFGPGEVLLQSAYLESPLDGAAPGTIALVLKRFSERDANDPG--A +KLLKLMAGTYTGRSRLRSGLAPGWRLAHKTGTGQATAVNDVGVMKAPDGCVYPVAVMVAE +TRAGTQATNALMQNVALAVIRH- +>[subseq from] D-alanyl-D-alanine carboxypeptidase n=1 Tax=Planctomycetes bacterium Spa11 TaxID=2528022 RepID=A0A518K6U5_9BACT +-qALGKALRPMLEGHQGAVTVAIKHLETGETF-TFDADRPMPSASMIKLPIMLTAYRAEL +RGDLSMDDKLELKESDKVPGSGLLTEHFTPGLTLRDAIRLMMGWSDNTATNLVIEAIGGI +RSVNRLMEGLGYDNMRLNSLVFRGDTTIAPERSGVMTAAETIDLYEKIVKDEDEIEEARK +EMLDHLRACQS-KDTLPRLLPKGTTVAHKGGSVS-ASRCDGGVIESPTG-PIAVCVMTTD +NKDTEAEPMTLIAQVGKAAFDYf +>[subseq from] D-alanyl-D-alanine carboxypeptidase n=1 Tax=Planctomycetes bacterium Spa11 TaxID=2528022 RepID=A0A518K6U5_9BACT +---------------------AIADGETGKLLwGYNDAGTRDPASTTKMMTAYVVLKIAE +EDPKVLDEVITFSERADKTGGSTSAVKAGEKVTVRELLYGLMLPSGNDASVAFAEHFGDE +SAYDRFIAKMNATAKELGMDGTGYNTHGLTAEGHVTTAQDLVKLAHAAMQNELFR----- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Halomonas sp. MES3-P3E TaxID=2058321 RepID=A0A2N1APX6_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +QRAQALARALGVRTESFTQDYDQAFDAYEATGENVGTLRAFGDLLASLHGGDDLSAEQRQ +TLLAVMQRTSSGKRRLKAGLGEGINFAHKTGTQQR-RSCDAGIAERATEGPWVIVSCTRG +PAA-VSAHERALASVGEA----- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas daroniae TaxID=2487519 RepID=A0A4Q9QQE6_9PSED +---LLERLQAVAAKQDGELGVYVKDLHSNLAV-TLHAEELWYMASGIKVPVAIAVLRGVE +RGEWNLDTRLILAANDFVDGAGSTNQHGPGALSVRFLLEQMIIYSDNTATDRLIRLV-GL +DAVNRLVSELVSEGFEPITSLADVRHHYYSRNLNAARLSAYGELLERLAEGEALGAEQTT +YLLGVMSRVKTGSKRIIAGLPADAHFAHKTGTQR-ARICDSGLIDTPARAP-VLVVACVQ +GESSLAKAERSLRQVGEALA--- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A3B9YNN0_9BACT +--RMNAQLETEARRFPGRIAIFTKDLKRGWEW-SYHSDDLFPSASLIKVPVMIGVFEKIN +RGEMALGQQLQLKRRLRAGGSGSLKWSRDGILTVRQLLDHLIMESDNTAMRILIDEV-GI +GYLQRQFQRIGLVYTEIYPEGLSLSSS-RVRYENFTTAREMSMLMEKIYRGEMVDRFSSG +LMLEILKQKKA-PSRLAKHLPIGWQIAHKTGLLRR-ACHDSAVIFSPEGD-YLITVLTGQ +NT-DYSSAKDHIARLGAITYDHy +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas daroniae TaxID=2487519 RepID=UPI0010385B88 +---LLERLQAVAAKQDGELGVYVKDLHSNLAV-TLHAEELWYMASGIKVPVAIAVLRGVE +RGEWNLDTRLILAANDFVDGAGSTNQHGPGALSVRFLLEQMIIYSDNTATDRLIRLV-GL +DAVNRLVSELVSEGFEPITSLADVRHNYYSRNLNAARLSAYGELLERLAEGEALGAEQTT +YLLGVMGRVKTGSKRIIAGLPADAHFAHKTGTQR-ARICDSGLIDTPARAAPVLVVACVQ +GEPSLAKAERSLRQVGEALAQ-- +>[subseq from] serine hydrolase n=1 Tax=Marinobacter sp. JB02H27 TaxID=2597703 RepID=UPI001245D627 +-tDLEQRLGEIDEDYPGELGVFVHNLKNDEKA-SLRADEPWYLASTVKVPVAMAVMETID +RKDMTLGTTVTLEPTDFVDGAGETNKSPGDKVTVQYLLEQMLIHSDNTATDVLIRLV-GM +EAVNELVAVNTDGGIGKVTTLADVRRSYYGSGLNSGRLDDFSILFEALAKNQVLGKSSRD +YLLSVLERIETGDNRVKAGLPEHVRFAHKTGTQHR-RACNIGLATVKDHP-GVIIAACGR +HTADLAASEKAFRQVGKAVAD-- +>[subseq from] Beta-lactamase n=1 Tax=Fimbriiglobus ruber TaxID=1908690 RepID=A0A225DJZ1_9BACT +---LEALIAPIAKEHHGKVAVGVKHLVTGESY-YLNGDDVMPTASLIKLPVMVEAYWQAE +EGKVKLDEQIVLKADDKVPGSGVLTDNFSPGLALRDAVRLMMTMSDNTATNLVLDKI-SI +PATGVRMEAIGLKETKIHSKVFRGTTTIDKKRSGSTTTKEMVQLLEKIHKGEVVTPKACE +EMMAILGKNQD-NEKLVRLLPPGTKVAHKTGSLN-AAKTDAGIVYLRDKPAFAICVLTNE +NQDQDNAAQLTIARIARAAYDHf +>[subseq from] Uncharacterized protein n=1 Tax=Sphingomonadales bacterium 24-56-14 TaxID=1970588 RepID=A0A258Z977_9SPHN +-eTLRNDIDTLWKKFPGRAGIAIYTPFSDDII-GRRHTERFPQQSVSKMWVALTILEQEA +AGKLSLDKRIRVSRDDIVVSQPIKQYLSDKDMSVRELLAHAVNASDNLANSVLIRVAGGP +QAINQMLDRRKVQSIRFGPGEVLLQSKYLASPLDGAAPGTIALVLKRF--GERAPDDPGA +KLLKLMAGTYTGKSRLRSGLAPGWSLAHKTGTGQSTAINDVGVMKAPDGCRYQVAVMIAE +TRAGREVTNGLMQNVARAVVRH- +>[subseq from] Serine hydrolase n=1 Tax=Limnothrix rosea IAM M-220 TaxID=454133 RepID=A0A1Q4R6E5_9CYAN +-----------AADPELDATLLFVDLDTGEYL-DVAASRSVSAASTIKIPVLVAFLEAVD +QGEVQLKEQLMITENVKGGGSGNLQYKDNGTFSALFVASEMSINSDNTATNMIIEQLGGF +ETLNLKFQRWGLKQTQLNELLPDLEGT------NQTTARDLAFLLAKINQGNILSTRSRD +RLMRIMSATSN-NRLLPQSLGQGAAIAHKTGDIGF-IIGDAGIVDMPNGKRYIASIFVER +PY-NAEKGRELLHQIGRQFYQY- +>[subseq from] serine hydrolase n=1 Tax=Acuticoccus kandeliae TaxID=2073160 RepID=UPI000D3E795B +--SLLAELARLGEGAAGDLAVAALHFASGRRV-LMNEAGHFPPGSAIKLPIALRVLERVD +RGEITLDTLVEVRPAEMNPPGGLGELFRAPGLSVRNHLEGMITRSCNTSTDVLIRVAGGM +AGVADWVARAGIGDFACTLTMREALCRFRHDERDLCEPRAMLELLRRLHARDGVSPAAAS +VLTDTMTRTVGTRDRIGARLPEGVATATKTGSGA-GTAVDVGFVELPAGGTLALAIFVMG +SRRDMATRNRAIADVARLVVDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora palomenae TaxID=1461247 RepID=A0A561WCD0_9ACTN +---LTRQLAQVVAATNNRAGVTVRDLSGNQQI-AVNGTFRPKAASVIKLWILVELLRRVD +CGQLSLDREVRVTRADVVGGAGKLKSEPIPQVTTHRLAEYMIEYSDNTAANVLIDQLGGF +APVNALIDSMNQRDTVLAHKLFDGGAD--RGEENYTSPDDVISLLGAVWDARILTEPSRD +LMIGFMRNQTR-NSKIPAALPPGTPLAHKTGDDTD-ASHDVGYCLTPGA-ETAVAFLTTG +PFRS---GSETVRQLARTVSD-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7XU06_9BACT +-----------ERHALEKLGIAFWDSETTLQW-AYNADEYFHAASTMKLAVLLGVYREVG +RGELTLDAPVHVRNKSVVDDQLYMYRNLGRTMTVQQLAHAMIATSSNFATNLLVDVV-GV +PVIQTALSELGIDGVRVVRGVEDQ-AAFEAGINNEVTAAGLLKLLRAMVEGRAYGPDASK +QMLEIMHDQRF-RSGIPAGLPQAARVAHKTGNIAT-VHHDAGIVYLEKRKPYVLVILTQF +HHE--TPRGTAVAEISRDIYE-- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A537KG71_9BACT +--SLKENIYQELSKQEGTFAIAFKDLSTGKEL-LINDTVTFHAASTMKTPVLVEVYKQAA +EGKFSLSDSLVIKNESIVDSSLFSYKHIGEKRTISFLLYQMIIVSSNFSTNLIIELV-GA +KNVSATMQQLGAKDIHVLRGVEDGK-AFEKGLNNTITAHGLMTLFEKIARGETVNPAASQ +AMINILLDQKF-NDIIPAQLPANVKVAHKTGSIT-GVHHDSGIIILPNGKKYVLVLLSKN +LK-DEKAAIKAMANVSKLIYE-- +>[subseq from] Uncharacterized protein n=1 Tax=Bryobacterales bacterium TaxID=2026791 RepID=A0A350UEZ7_9BACT +--KTLAAIADLDRSFDGAIGVAALDLTTGRTF-AYHGETVFAQASSIKIPILMRAFQAAA +EGRFSLDDQLTLTTKDTVGGSGQLQRLLESGLSIRDLLTAMMRDSDNVATNRAITLV-DM +ASVNRMLDELGFLNTRLRRIMIDSGAA-QRGLENVSTPLEMVRLVRLLHDGAFISPRASD +EMIAIMTLV---DASMRKAIPEEIRVASKPGGVP-GVQCETGIVYLRHR-PFALSVMSAA +APEGAP---NPVGAITSIVL--- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus sp. TaxID=1882945 RepID=A0A3E0RE22_9BACL +-----PSLERLTEETGGQWGIYLEDVRTGERL-GIAEHQRFYAASLIKVPIMTAVFAEAY +AGRLALSDKLRLRREDQVGGAGVLQHFTPGTLTVYDAVTLMIIQSDNTATNMLIDLI-GT +DAIRTAMSRTEMVNSSFYNKLMIVPAEPEG--YNEVTAADMGSHFRFLATGKAISYNSCL +QMINILKRQQH-RDRLPCRLPPKWELANKTGTVTN-ITHDAGILYVGGHA-VIICALSKN +VD--AKAAGEVMGQIGRMVYDLy +>[subseq from] Serine hydrolase n=1 Tax=Gemmataceae bacterium PX52 TaxID=2598579 RepID=A0A5C1AJT5_9BACT +--TLASRIKPFADAHKGKVAVAVKNLATGEAF-DLNADEVMQTASLIKLAIMVEAYRQAD +EKKTDLGKMVTLAKDDKVPGSGILTSHFSDGFPLRDAVRLMIVYSDNTATNMVLDQI-GI +KPVNAMTAALGMPETRINSKVFKRSTRSEKYSLGSITAKDAVNMLELIHTEKAASPDSCK +AMLGHLKVCDD-KEKLTRFLPAGTVVAHKTGSTDR-VRTAAGIIYVPKTIPVAVCVLTND +NQDQDNAGQVMIGKIGKEVYDFf +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9RFK5_9BACT +--DLQDKIAQIRSQFPGEMSIYMKNLDSGDEI-TVDSDKVFETFSVIKLTIAAELMHQVE +GGKFSLSDRIPLTAGDERLPSGVLYALDPGLPTVNDLLTLMIILSDNEATDILADKV-GR +ENITTYMHSLGLANTSIRYADLDWDRYDAGIYFGHSTTREIGQLLEMMARGKLVSKSSSD +RLLGIMEKQQV-NDRFPRYLK-DVRIAHKTGDGQPFIANDAGILWVNG-EPIVLVVFTGH +HRGTTASLHDAIARIAAYVVQYy +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium TaxID=2044944 RepID=A0A431MUE1_9SPHI +-nAMEQQVKQKLAEQKALFAVAFKDLKTGKTL-LINEHQYYHAASTMKTPVLVEVFKQAA +AGKFNLTDSIMVKNSSIVDGSPFTYSYIGRKRTVYQLAYDMIIASSNLATNIIIELV-KA +ENVMKTMKELGANDIKVLRGVEDSK-AFEKGLNNTTTAYNLMLVFEQIAKRKLVSKKACK +EMIKILLDQQF-NTIIPAQLPANVKVAHKTGSIT-GIHHDSGIVFLPDGRKYVLVLLSKF +EGAE-EGPTTTMASVSKIIYDY- +>[subseq from] Serine hydrolase n=1 Tax=Acidovorax sp. Root217 TaxID=1736492 RepID=A0A0Q8T1T7_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +KRVDALARTIDVATTDLRKTMDEAYARYYARGLNSAPLTSYGGMLEKLVTGKLLSPAHQQ +RLFTDLKYATYDAYRLEAGLPRSERFIHKTGTQLH-RACHMGVVNPQDGGRAAIVVATCA +EDDEHGEAGRAFEQIGRALTQTf +>[subseq from] Uncharacterized protein n=1 Tax=Peptoniphilus sp. HMSC062D09 TaxID=1739305 RepID=A0A1E9APW9_9FIRM +---LNEKISSLLNNVEGEFGVYFEDIQDHNKV-MINENLIFCAASTIKIPLVALVLKEYE +EGKFDINDKVDIKLENRVGGTGVIRNLDKSFPTILNLINLALVVSDNIATNQLIDIVGGF +GKINEFNQSIGLNNTKFQRKMLDLKSL-NEGLDNFTTAKDLGTLLTLIAEGKCVSKKSSE +LIIKILKTQQF-RQKLPNFIPAVVMVANKTGDLWK-TQHDVGIFILPKGERYVVAVYSQK +LSED-YEGIEAISKISKIVYDY- +>[subseq from] serine hydrolase n=1 Tax=Bacillus mesonae TaxID=1193713 RepID=UPI000834FC4C +---IKKEIMTVLAGIKGKAGVAIEI--DNECF-YYHNEEVFPSASVIKVPILIEGLRQAE +NGTITLNDMLPIRE--RVGGSGVLQALSDQSMSVKDLLTLMITVSDNTATNMIIDLL-GL +DSINKTMETLGLQKTALQRKMMDFAA-VKRGLNNITCASDLIICLKVINEGEYLSEESRT +LALTMMNYQQFHDKLTARVDPDKVFVASKTGSLP-GVENDCAIFKYRGKT-AYAAILTEK +LE-DEYSGRQVISQIGKYLYDY- +>[subseq from] serine hydrolase n=1 Tax=Chitinophaga sp. XJ-2 TaxID=2164099 RepID=UPI000D6BE052 +-hKLTAKLQALAANFQGEAGIYVENLKTGRFV-AINADTVFPTASIVKVPLLVGLFDKIE +KGELKYHQPWTYRDSSKYGGSGIMQFFRDSATEVSVLAALMMSYSDNTTSLMIQSMAGGG +ARVNELMEQYGLKDTRVNSRTPGRAEIWKKYGWGQTTPREMARLVKMIRKGEIISPAASD +RMYRLMCRGYY-DESSLSQLPPYVQAAHKTGSVD-ATRSEVVLVNAPHGD-YVFHVATKN +NKSDDNEAVVFIRNVSAVIWNHf +>[subseq from] serine hydrolase n=1 Tax=Saccharomonospora sp. CUA-673 TaxID=1904969 RepID=UPI0009FA25AB +--DITGQLHAVETRFGGRLGVYAVDTGNGFAV-RYRERERFLMASTAKLPIVAATLGRGV +----PLDQPVPIRQEDVLEYAPVVAERVGQTMTVAELCDAAITQSDNSAANLLTAQVGGP +EHVTGFLRETGDRVTRLDRWEPELNTR--STSLDTTTPAAMGDCTRTLLFD--------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Pontibacter korlensis TaxID=400092 RepID=A0A0E3UUX8_9BACT +-qQTERQLGELISRSPAITGLVAVDLTTGDTF-SFNADVVFPQASAIKVPILMSVYKQAH +EGKFTLSDKREVAATDVVGGTGILKDLVDLPVSIRNLGVLMITLSDNTATNSLIDLV-SM +QEINSMLRSLGAKQTLVQRKMINSAA-SGRGEENLSTPADAAKILQLLYKGEFINKTTSD +EIISILKKTDRQTSRLATRLPGHVPIAFKPGVLN-GVSTEWAIILLPER-PYAVAVMESY +KV--EGQAEHTVEELSEVLYQYf +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus mesonae TaxID=1193713 RepID=A0A3Q9QYH9_9BACI +---IKKEIMTVLAGIKGKAGVAIEI--DNECF-YYHNEEVFPSASVIKVPILIEGLRQAE +NGTITLNDMLPIRE--RVGGSGVLQALSDQSMSVKDLLTLMITVSDNTATNMIIDLL-GL +DSINKTMETLGLQKTALQRNMMDFAA-VKRGLNNITCASDLIICLKVINEGEYLSEESRT +LALTMMNYQQFHDKLTARVDPDKVFVASKTGSLP-GVENDCAIFKYRGKT-AYAAILTEK +LE-DEYSGRQVISQIGKYLYDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora coriariae TaxID=285665 RepID=A0A1C4V3N6_9ACTN +------------------SGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQASLDDGVLVTPADVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNIAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGDILSPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---DTGDETVRRMARTVYDY- +>[subseq from] serine hydrolase n=1 Tax=Emticicia sp. CRIBPO TaxID=2683258 RepID=UPI001412FC36 +-----------------IVSVTVLDKSGEVRY-AKNEKLRVPSASVIKIPVLIELSQQVD +EKRVKWKEKIKLHTEDRVGGSGDLQYEAAGKFTIEELAVKMIAVSDNVATNLLIDRI-GM +ENVNLGLENWGFDETRLNRKMMDFK-AIQEGKQNYITSFEVSKMLWGLLTKRILKDQSSK +KALEILLKCED-VTTIPRKIPKTVPVAHKSGTLDY-VRGDAGIIFS--REPVIVSVFVQN +FE-SQEQAEKIIGELAEIAYQTy +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. PA27(2017) TaxID=1932112 RepID=A0A1Q9Y9B3_9PSED +---LLERLQATAAKQDGELGVYVKDLHSNLAV-TLQAERLWYMASGIKVPVAIAVLRGVE +RGDWQLDTRLPLAANDFVDGAGSTNQYGPGELSVRFLLEQMIIYSDNTATDRLIRLV-SL +DAVNALVRELAPEGFEPITTLGDVRRAYYRSNLNAATLSAYGELLERLADGQALGQAQTA +YLLAVMGRVKTGSKRIIAGLPKDAHFAHKTGTQR-ARICDSGLIRTPEREPVLIVACV-E +GELSLAKAERTLRQVGEAL---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T5D2_9BACT +------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD +VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP +DAVTTFLRSMGDEVTQLDPWETELNEATP------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora palomenae TaxID=1461247 RepID=UPI0012BA0800 +---LTRQLAQVVAATNNRAGVTVRDLSGNQQI-AVNGTFRPKAASVIKLWILVELLRRVD +CGQLSLDREVRVTRADVVGGAGKLKSEPIPQVTTHRLAEYMIEYSDNTAANVLIDQLGGF +APVNALIDSMNQRDTVLAHKLFDGGAD--RGEENYTSPDDVISLLGAVWDARILTEPSRD +LMIGFMRNQTR-NSKIPAALPPGTPLAHKTGDDTD-ASHDVGYCLTPGA-ETAVAFLTTG +PFRS---GSETVRQLARTVSD-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A165P2V7_PSEST +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYAGQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVTCAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] serine hydrolase n=1 Tax=Gelidibacter japonicus TaxID=1962232 RepID=UPI0013D77FB0 +-eKFEQNIQAQIDSIDGNIAVAFYSLSQPKDSlLINVDEKFHAASTMKVPVMIELFKQDH +EGKIDLQDSILLKNESIVDGSLYSYSQIGTKVALSDLMHSMITVSSNLATNVLIELV-GA +KNTTATMRSLGARNIEVLRGVEDQK-AYDQGLSNSTTARDLMIIMEAIANNTAGRQGDCE +AMITILKDQQH-NDLIPMYLPKEVQVAHKTGSIT-GVHHDAGIVYLPDGRTYILVLLSKN +LK-DFDKGTDQLAKISKTVYDY- +>[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=A0A0E3UPZ2_9GAMM +--DLERRLQAIDAGLGGDIGVYVLHLERRESY-AYRADEPWYLASGVKIPVAIAVMRAVE +DGELSLDTRIALRETDFVDGAGGTNRHPAGALTVAYLLEQMVVFSDNTASDVLIRSV-GL +ERVNAVAADLIDAHMRITT-LGDVRRAYYATHLNSATLVDYGRMLATLAEGQALGDEGTR +YLLDLMARVQTGKQRIVAGLPRRAGFAHKTGTQYR-RTCDLGIATVPTGARVVIAACVRG +TG--TAAGERALRDIGAAVT--- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7MVS9_9BACT +---LRSRVEARIAQAPARVGLYYRDLTSGDSL-TVGSALRFHAASTMKVPVMIQLFRDRD +AGLLKLDDSITVTNTSIVDSSPYQYKGIGQRVSIRQLIELMETVSSNLATNLLIERV-GA +KRANATAHSLGADSLVVLRGVEDGK-AYRAGLNNTTTARDLGVLLAAIANGTAASPASCQ +EMLAILSRQQF-NEGIPAGLPAGTRVYHKTGWIEQVVYHDAALVEPSARSRYVLVVLTAG +IAKN-DDAYALVRDLSRLVFE-- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridium autoethanogenum DSM 10061 TaxID=1341692 RepID=U5RZ10_9CLOT +-----EKILDVIDLKKLNCAFVIKNLKTGEKI-AYNENVVVPSASLIKIPIMMEILNQVK +EEKLSLKQRITVEDNVKVPFSILNLLESGNSYTLKDVITLMIIQSDNTAANILMDLA-GM +DNVNNYIKDLEIKNTVLQRKMLDSKAR-KEGRENKTTAADMAKFFEIIYKGERAKECYSV +IMKNILTSQLD-NSVMRLNIPDDIRIAHKTGDLN-GISHDAGIVYLPNVD-YIFCGLTWD +AV-TNNFARETIGKISKVAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. TaxID=1506 RepID=A0A352NTD3_CLOSP +------------------CAFEVKNLKTGEKI-SYNENTVVPSASLIKIPVMMKIIELVK +EGSLSLKQRITVTDEVKVPFSILTLMESGNSYTLKDIITLMIVQSDNTAANMLIDIA-GM +NDVNDYIKKLGLKNTVLQRKMMDSKAR-EEGRENKTTAADMVKFFEQIYKDAESGSPYGM +LMKNILTAQLD-NSVMRLYIPDSTIIAHKTGDLD-GISHDAGIVYLPGIN-YIFCALTWN +APN-NNLARDTIGKISKTVYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A354MR59_9FIRM +-kDLASRLSAVMDAFPARTALYCVDLTTGAPIaAIRENTRVVSASTIKVPILCCALQDVM +DGKLSLDQHLAIAPADFCSDTEVFEPYRQDGASLWEMLYWMIVSSDNTATNTIISLL-GH +DHVNQYCRTIGLTQTSLQRKMLDFQ-AIAEGRNNYTSPADLYRVFSLLYHGEILNKPLRE +VAFDFLSRCRS-TDALQRYIPDAVTVLHKPGGLDH-LNHDAGIFLTEDR-PYYLGIFTWD +GPDGQPQQNRLIGQLSRMIYDA- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Caulobacter TaxID=2648921 RepID=A0A2R7LG72_9CAUL +------------RAAPAVLGVGLLDGQTGQLL-GFNGDRPFPLQDLSRLAIVAAVLAEVD +AGKLSLSEPVIVRDIDLSPPSPVAEAWPGRTYTIGDLVDRTLSTADNTAADLLMKRIGGP +GAVSAWLELKDISGLHLDRREPEINAAYLTDGRDTVTPLAAVRFLDALRAGQLLSPASTG +KLLGLMALHRPGGDRLAAALPAGSILTHQTGNVRAAATSDIGIISLLDGRQFVVATFLGA +SSASDQVRSALITEVGRTIL--- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella buccae TaxID=28126 RepID=Q8KT58_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNGFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNDASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMFMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase class A n=1 Tax=Tumebacillus sp. BK434 TaxID=2512169 RepID=A0A4R2R5C1_9BACL +--ALTPALQRMIEAARGTYGISIYHLESQSEF-TYQPDEWFYAASIIKVPIMAAVFDQAF +KGNLRFEEKIALRAEDMVTGSGLLQNLSPGLLSIYDYTMLMIIDSDNTATNILIDRI-GT +QAIQDAMAEWGLTGSGFYNKISVIPAKIEN--YNKITPRDMTHLLKLIADGKVVSWRACA +EMVKIMKQQKY-NEGLPSLLPTQWECAHKTGWVN-GTDHDMGLLYFPRN-TFAVSVFSKN +II-ERKDAHGLMGQIGRLLYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A399ZUW7_9CHLR +--ELRIQIEDIIAGVQADLGVSILHVESRATV-DITADTPVPLASVVKIPVLLEAFRQLG +EGRFQLDDRWPLEHAYKALGSGILTQFDDGLPTVLDLITLMIIVSDNTATDILMQRL-GV +QAIDDFMHRLGLTQTHVAHTLGEIFAYSLSADNNVGTPRELTRLLEMIYAAGVLDRGACD +QMLQILLKQQL-NDRLPRFLPAGTPIAHKTGTFS-GVRNDCGIIYVSEASHVVVTVLGTW +DH--------------------- +>[subseq from] serine hydrolase n=1 Tax=Agrobacterium sp. LAD9 TaxID=2055153 RepID=UPI0012906067 +------------------------------------------------------------ +-------------------------------------------------------TIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADIVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Serine hydrolase n=1 Tax=Emergencia timonensis TaxID=1776384 RepID=A0A415DVK0_9FIRM +---LKEQLIAYLNKEKVQGAFLIKDLSDGETF-CYNEYLKVPSASLIKMYILVEAFRRIK +GGLLTLDEEIAVQKEDLVDFSVL-QFLRPRIYSLEELLRLMVVYSDNTATNVLVDYF-SM +SSLNELMQQIGCKTSVIQRKMMDFAAA-EEGRQNYTSVIDMASLLERLYQGKLLGQPFDA +QMLDIMKGQAD-EEAMRRDLPDELIIARKSGELD-ALDHDIAIVYAEKRN-YIYVFFSWE +-TGDNNRGRKVLAETSRLVFDYf +>[subseq from] Uncharacterized protein n=1 Tax=Xylophilus sp. Leaf220 TaxID=1735686 RepID=A0A0Q4GP91_9BURK +--RLVHDLAQVSAGHSAGIGVYVRDLDTGVSA-RFQSSESWYLASTVKVPVAIAVLRGIE +RGQYKLDTTVTLEASDYVDGAGLTNRNPVGSLSIRYLIEQMIVHSDNTASDMLIGLV-GV +DALNALVAELVPQGFGRITRLAEVRRAYYASGLNSARLDAYGELLARLAQGQALGPASTD +YLLRVMERVATGTHRIKAGLPPGVVFAHKTGTQRR-RFCDAGIAYTPAAG-AATAAPTTP +PHAGHPHRAVV------------ +>[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0006220BD3 +-nSVQQQLEALVKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE +SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP +DKVTAFARSLGDETFRLDR----------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Micromonospora arborensis TaxID=2116518 RepID=A0A318NIK7_9ACTN +------------------AGVTVRDLSGDQQI-AVNGALRPKAASVIKLWILVELLRRVD +CGQVSLDDGVLVTPADVVGGTGQLQFETPQVVTLRRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. OK042 TaxID=1884381 RepID=A0A1I4CPX6_9BACL +-eQLREKLTQLLDKAEGSWGVVVEDLDRGQRF-AHRPDEAFIAESVIKVPIMAAVYAAAA +QGAFQLDDRIPMRAEDQVGGSGILFALSPGLLTIREWVTLMIIQSDNTATNVLIDLV-GR +QRIEQTMIELGMEKSKYSRKLMIYPVG--ITENNMITPGDVSRMLGSIATGGFLSHHACE +EMVSIMKRQQV-LNGLPSLLPPDWEIACKSGWDS-GRQHDVGVFYSQGR-RFSIVALSQD +VQ--SESALRVLGQIGKEVYEY- +>[subseq from] Putative beta-lactamase n=2 Tax=Desulfovibrio piger TaxID=901 RepID=B6WTZ1_9DELT +--SLERDIHALMRDKKALAGVALL-TEDGLCA-GVHMDTPFPLLSVIKFPLAVAVLEKMQ +QEHTPLTTRIPVRAGQLHPHSPLRDKYGQRDLSLQELLHATVTFSDNNGCDILMDYVGGP +SVVEACARRLGADSVFIGHNEDWMHQNIYNQYANWGTPRSMARMLLGFFSSPDIPQAHKD +FMAGIMAKTPALPGKILEGLPQGMTAGHKTGSSDRTADNDLAFFRLPDGRYVALAVFLCN +SLESPETNLSLITDITRLSV--- +>[subseq from] Beta-lactamase n=1 Tax=Calothrix sp. NIES-3974 TaxID=2005462 RepID=A0A1Z4NG73_9CYAN +---LDTQIRQLMNRYSLSPGMFFVDLQTGDYL-DINGDRIFSAASTIKFPILVALFEEIE +AGRIRLDELLVERADLKVGGSGDLQYKPAGSFTVLETATKMMTISDNVATNMIIDRLGGK +NVLNKRFRHWGLQQTQINHLLVDEYG------TNKTSAKDLVKLAALVVNNQLINENSRT +HIYNMMGNCHN-QSLLPKGLGTGAKIYHKTGTLRF-VLGDAGIVKTASGKVYLAGIIVQR +PNHD-ESAIRFIREVSRLVYNYf +>[subseq from] Beta-lactamase n=1 Tax=Anditalea andensis TaxID=1048983 RepID=A0A074LF54_9BACT +---LRTEIQQAFSEVEGDFGLAFKYLGNDNHSlYINERENFHAASTMKTPVMIEVYKQAA +AGKFMLTDSILVHNESIIDGSPYSYHQIGNKTTIYDIVYPMITRSSNLATNILIDMV-GA +ENTTNTMRDLGAKDIQVLRGVEDQK-AYDAGKNNTTTAYDLLVIMEAIATQTAVDPHADQ +EMFKVLADQHF-RDLIPADLPEEITVAHKTGFIT-GVQHDSGIVRLPDGRQYVLVILSKN +LN-DSTQGKQVIAKVSRKIYDY- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI001362A828 +--TVEGTIQDAFGDISGDIAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] Serine hydrolase n=2 Tax=Pseudorhodoferax sp. Leaf267 TaxID=1736316 RepID=A0A0Q4XSG0_9BURK +-----PELARIDAEGGPRIGVYVRDLATGASA-SHHASEHWYLASTVKVPIAIAVLRGIA +RGDYDLETPITLRATDYVDGAGRTNSPVGTGLSIRFLMEQMIIHSDNTASDMLIGLV-GL +PQVNAVVQAIAPDAFGPITTLAEVRRAYYASGLNAGRLDAYGELLAQLVDGKLLAPEQTR +YLMGLMERVATGTQRIQAGLPPGARFAHKTGTQR-ARFCDAGIVRTATGERGVLVVACTQ +GDLSLVRAERALRQVGTALC--- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8CLK0_9BACT +-qRLEASIQRTTRSVNATWGIYLKSLETGEEI-ALDADRQMETMSTIKIPLMVEVFAQIT +RGRFSLTDKYTFAPADSQPGTGTIQRLDPGAMTVKDLITMMIIVSDNTATEVLYRMVGGV +AAVNARMDALGLKQTRAMRWFPLLRARDGKSPFGLSTPREMGRLLEMMERGTLVDKVSSD +LMLRIMRGQLY-RTRIPRYVT-GYTIPHKTGDFLPYVGDDVGMLEAPDRT-IIISIFTGN +HFGSGEALENAIGLVAKDVADYf +>[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=UPI0009E22F29 +--DLERRLQAIDAGLGGDIGVYVLHLERRESY-AYRADEPWYLASGVKIPVAIAVMRAVE +DGELSLDTRIALRETDFVDGAGGTNRHPAGALTVAYLLEQMVVFSDNTASDVLIRSV-GL +ERVNAVAADLIDAHMRITT-LGDVRRAYYATHLNSATLVDYGRMLATLAEGQALGDEGTR +YLLDLMARVQTGKQRIVAGLPRRAGFAHKTGTQYR-RTCDLGIATVPTGARVVIAACVRG +TG--TAAGERALRDIGAAVT--- +>[subseq from] Serine hydrolase n=1 Tax=Caldilineaceae bacterium SB0675_bin_29 TaxID=2605266 RepID=A0A6B1G2L9_9CHLR +--SLESDIRDISANSGAEMAVSALHLETGQHI-DVDAERVYPLCSVLKIPVLVEAFRQIE +DGLFTLDDRWQLTTAEKNLPSGILVFFDDGLPTVKDLLTLMIIISDNTATDMVMHRL-GQ +GSVTRTMHDLGLTDIHVPLTIRELFDYSLGPDNDTGTPAALTELLARIWRGEAVNRAACD +AMLEILLKQQL-NDRLPRYLPPGTPCAHKTGTLP-GIRNDSGIIYAGDNSHVAVTVFSRW +DDEA------------------- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7MU59_9BACT +----RERLAARVAQAPATVGLYYRSLTRPDSL-VLEANVRFHAASTMKLPVMIQVFRDAD +AGLLRLDDSLTVHVVSLVDGSPFEYGRVARPASVRDLLELMITRSSNLATNILIERI-GA +ARAQASARALGAWSIQVLRGVEDGK-AYRAGLNNTTTARDLGVLLAAIAQNRAASPASCR +EMLRILEAQEF-NEGIPVGLPPGTRVAHKTGWIGEVVYHDAAIVYPPSGGSYLLVVLTGG +IKQD-SVAHNLVADVSRLVYA-- +>[subseq from] Serine hydrolase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520G9T1_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +QRVEALRQALGVPRTSLKATIDEAYARYYEKQLNAATLEGYGAMLEKLVQGKLLKPASME +RLFTAMKIRIFTNYRLQAGLPRSASFIHKTGTQYR-RACHAGVINPQDGAKAIVVATCAA +DIDEQKDAGRVFEQVGRAITR-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora arborensis TaxID=2116518 RepID=UPI0011B696DD +------------------AGVTVRDLSGDQQI-AVNGALRPKAASVIKLWILVELLRRVD +CGQVSLDDGVLVTPADVVGGTGQLQFETPQVVTLRRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Serine hydrolase n=1 Tax=SAR202 cluster bacterium AC-409-J13_OGT_754m TaxID=2587834 RepID=A0A5N8YHP9_9CHLR +--------DEAIARVPGLVGFFAEDLTTGEHF-SHNADKTFFTASTFKVPLLVGLFTQVE +SGNIGLSERFKLKEDMKVAGSGVLKEMDPGILTIHDLAMLMIIVSDNTATDIIYDLV-GK +DNLREILAPLGLTNTRIPMTCRELLCGFNEETSDVSSPRDMANLLKFIERREVVSTKACE +QMLNILKRQQL-REMLPKKLPKEVHVAHKTGGYFR-VQCDVGIVYTSKS-SYSVAIMAKK +IT-DMRGIQDAVADLSEAIYFSf +>[subseq from] serine hydrolase n=1 Tax=Nonomuraea sp. NEAU-YG30 TaxID=2249762 RepID=UPI000DE1E16A +----------VFRAAGVTGWLHAADLDTGREV-GHGSDEPVPTASVFKVPLMVELCRQAD +AGLLDPAARVTVRAADRVFPTGVSAMLDDVTMSLRDLAYLMIAVSDNTAADVLSARV-GL +DAVNAMLSRFGLEGTRVRHTTAALFEVLDPRRANRSTPRETARLFGLIWRDEAASPGSCA +WMRAVLNKQVW-PHRLASGFPDDVDVSGKTGTLPT-LRNEAGVVEYPDGGRYAVAVFTRS +SSVNQPRADAVIGTAARMAVDH- +>[subseq from] Serine hydrolase n=2 Tax=Mycobacterium paragordonae TaxID=1389713 RepID=A0A386U3T5_9MYCO +----ERQVERRILAAPADVAVFFRLLGGESEW-SYQPDDTFHAASTMKVPVMIELFHQAH +QGQLTLDDPLLIHNESLVDGSAFYYSSEGQTRTLRQLCELMITMSSNLATNLLIKKL-GI +ENIRATVHLLGADGMNVLRGVED-NKAYDLGLNNTTTARALAILLSAIAEGKVVDSDASR +QMVEILKRQHI-NDGIPSGLDPTIPVAHKTGTLK-AIHHDAAIVYGP--QPFVLVILVRG +MAN-SKDSSALMADITRAFYR-- +>[subseq from] Beta-lactamase n=1 Tax=Chloroflexi bacterium OLB14 TaxID=1617415 RepID=A0A136KVD6_9CHLR +------QIENFISQFDKTISVSVYDLETNQEI-NINADVLMHPASVMKVPVMMEVFRLAQ +AGTLSLDDEIELYNSSIVDNSQYQYTKIGEKETIRELNRLMIIRSSNLATNVLMDKV-GT +KAINDFIQALGIKDMTVLRLIEDKL-AYGLGINNAFSARATTYMMRLIAEGKVVSKQASD +EMIQVMLGQEF-NESIPALLPKDVKVAHKTGWNED-LFHDSGIVFPPNRKPYAITLFTDG +FPNDNSQAHKCMAEVSKLVYE-- +>[subseq from] Serine hydrolase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=A0A2W5L635_VARPD +-eRLTNALERIDAAPGPRIGVYVRALASGESA-SFRAGQSWYLASTVKVPVAIAVLRGIA +RGDYQLDTPVTLRADDYVDGAGATNRHAVGALPIRFLLEQMVIHSDNTASDMLIGLV-GL +EQVNAVTAEVAPAGFGPITRLAEVRRAYYATGLNAGRLDAYGELLVQLADGRLLPPAQTR +YLLGLMERVVTGSQRIRAGLPAGARFAHKTGTQR-GRFCDAGIVQPAAGTRVVV-VACTR +GALSLARAERALREVGAALC--- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sporothermodurans TaxID=46224 RepID=A0A2T6EHN3_9BACI +--SLRKQIDGIIEQSLGIVSIVVE-INEETII-SKNSKREMSSASLIKIPIIMAAFQQAE +LGKIDLEEKIEVKPEHKVGGSGVIQYLTEGTLSVKDLLTLMIIVSDNTATNMMIDLV-GQ +ETINYFNKQIGCNHTRLERRLMDYVAR-DMGLDNVTSASDMVIFLKEIVENQFLTSKSTY +EILNILSGQQF-QDKLPAMMDDHVFVANKTGEIP-GVEHDVAIIRHNDD-QVFMAVLIDQ +LE-NQYEGKQIIARTGKAVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus borstelensis AK1 TaxID=1300222 RepID=M8DDI2_9BACL +-kSLQEKLETIIAAAGGQWGVVVEEINGSFYW-EHNTTQTFAAESIIKVPVMAAVFDAAS +KGKVRLDETVLMKQTDQVAGSGVMQHLTPDTYPVYDLITLMIIQSDNTATNMLIDLI-GE +DQVRLTMAELGMHDSCYSRKLMLYPAD--SPPNNMITAGDIARMLKRLATGTFLGEHACR +QMIGIMKKQQV-RNALPARLPAVWEMANKTGWDT-GRQHDVGILFAGGK-AYSLTALSEN +APPD--ASLQAMAAIGYEVY--- +>[subseq from] Beta-lactamase AST-1 n=1 Tax=bacterium HR28 TaxID=2035423 RepID=A0A2H5Z476_9BACT +-----RAIRLALEQVPARVSLSFCDLDRQWKI-AHDADHPVTAASTIKLLVLVTLYRAFA +RGDLDPNESIALTPDAVVPGSGVLRWLRHRPLTLRDLAVLMVIVSDNTASNLLIERL-GW +SAFAALATELGLAQTALRRRFAGR-AALPGEEENVTSARDLAQLLASLEKGKIVPEPWLE +DLRTILTAQQF-RDIIPARLPADVRVGNKTGSLP-GFLHDAALLWAPHGR--ATLVLLAR +DVHDAELTRRALADLARAVYDEw +>[subseq from] serine hydrolase n=1 Tax=Xanthomonas sp. Mitacek01 TaxID=1732019 RepID=UPI0006DB8C12 +------------------------------------------------------------ +---------------------------------------------DNMAIVRLRNAEAGE +ARLQALARELGVARTDLDATLEGVFDAYYRGDRNTATLPAFATLLDRLAAGELLSPDSTR +LMLDHMRGISTGNRRISAGLPPGTDFAQKTGTQLR-RACNVGVIDPEARDGATLVLACAE +DFDDIVDAETAFQGLGRAL---- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora palomenae TaxID=1461247 RepID=UPI0012B9C903 +------QLRQVVDAATANAGVTVRDLSGQQQV-SVNGTLRPKAASVIKLWILVELLRRVD +CGQVSLDQGVLVTAADVVGGTGQLQEQIPQVASLHKLAEYMIEYSDNTAANVLIDQLGRF +APVNALIDSMNQRETILARKMLDTEAA-ARGEENYTSPDDVVSLLGAVWDARILTRASRD +LMIGFMREQTL-NSKIPAALPPGTPVAHKTGDLPD-ASHDVGYYLVPGA-ETAVAFLTAG +PY---DSGSETVRRLARTVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Marinamargulisbacteria bacterium SCGC AG-414-C22 TaxID=2184344 RepID=A0A328RDT2_9BACT +---LQTELDSVIKHQPYTIHFGAYHVESGDYV-YLNPDKRFPMASTVKVLFALTALDLVD +QGMLSLDQTLTLTKKDIRPYSVLSLFARDPQMTLENAVEAMLIYSDNSATDAVFHACGGK +KAVNRFLKKHQLQSLTVSGSILAMLAQFFKSPKDTSTVRAWTTLFTKLLNGDLLSDQSTS +YVLTVMNQSHWGKKRIKGFLP-HVQVSHKTGSFSK-CTNDVGLITLPNKGHLIIAASVID +REPEEAKRDHVIALLTKTVYDFw +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus sp. SCSIO 07484 TaxID=2496837 RepID=UPI000F82D386 +--RIGETVASLVEAAGGTWGIVLERLGTGESW-CLNGDRPFYAASLIKVPIMVAVFADVE +EKKYALADRLPVRQEDMVGGAGVLQHLTPGEYPIHDLVTLMIIQSDNTATNILIDHV-GR +ERIRAIMKKAGMQNSRFYNKLMVIPAELEG--TNQVTAADMAELFRRLAGGRIISYDSCL +RMIAILKRQQI-RQSLPLYLPEPWELAHKTGSVRS-IEHDVGILYVGR-DAFLLSILSQD +VPS--QLARDTIGRICLAVYE-- +>[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium HGW-Elusimicrobia-1 TaxID=2013763 RepID=A0A2N2F0G8_9BACT +------EFERISAALGARVSFYYKDLSDNFEY-YHRPDDPYPSASLVKLPVMACVMAAVE +ENRLPPDLSIVYRSRHRVGGSGSLRYRYGRRVGLDELTYRMIVESDNVATNMICDTL-GL +GYINEKMLGWGMDVTDMKRWVLDLRRR-NQGVENYTTSREMGMLLEKIYRGQLVSRRASM +QMLEIMKNQHY-RNRIPRYLPPGVVVANKTGLMRN-VVHDAGIIYSTDGD-YVLCVLTRD +IP--SKTAARLIGEISHLIYD-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium aurantibutyricum TaxID=1551 RepID=UPI00098C3770 +--ALDNAIKNILALRCEDISLVFLDLNNTSNYiYINENKIFPSASTIKVLILAEALNEVL +NGKLSLDAPIEVKTSDKVPYSILTS-LTNNKYPLIDLLTLMIISSDNTASNILIDLL-TM +DSINNYGQSIGLKNTSLKRKMMDSKA-VQRGMDNLTSALDMLTLFKKIYNHELLNPKMCD +LILKILGNNTD-KEVLLRYLDADIRCAHKTGDLSN-LNHDIGVFKTKTS-EYILGVFVRN +ADFN-YVAKDLIGKVSKIVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora palomenae TaxID=1461247 RepID=A0A561WCH0_9ACTN +------QLRQVVDAATANAGVTVRDLSGQQQV-SVNGTLRPKAASVIKLWILVELLRRVD +CGQVSLDQGVLVTAADVVGGTGQLQEQIPQVASLHKLAEYMIEYSDNTAANVLIDQLGRF +APVNALIDSMNQRETILARKMLDTEAA-ARGEENYTSPDDVVSLLGAVWDARILTRASRD +LMIGFMREQTL-NSKIPAALPPGTPVAHKTGDLPD-ASHDVGYYLVPGA-ETAVAFLTAG +PY---DSGSETVRRLARTVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7SEI9_9BACT +----------IARAPATAVGLYYHNLTRPDSI-LIGANLRLHAASTMKVPVMIQIFRDAD +AGLLRLDDSLPVHATSLLDGSPFDYLRLGGKASVRELLELMITRSSNLATNLLIERV-GA +ERAQGTARSLGAWSIQVLRGVEDGK-AYRAGLNNTTTARDLGVLLAAIAQGRAARPASCT +EMLAILGRQEF-NEGIPAGLPSGTRVAHKTGWIGEVVYHDAAIVHPPRGGSYVLVVLTGG +IKED-SVAHSLVADLSRMVYE-- +>[subseq from] Serine hydrolase n=1 Tax=Terrabacteria group bacterium ANGP1 TaxID=2569760 RepID=A0A537IPD5_9BACT +---VPEEVQRLAEGFSGVLGVWSHSFTSGETL-EWNAGEVFPAASAIKLPILYEVYRQAG +EGRFRLADTRSVQAADVVPGSGVLKDLTPGVLSIRDLATLMIVVSDNTAANLLIDLV-GI +DAVNRSMRALGLGASVLEHKF---FHAPPGAPPSRSTPADLGSLMMQIAGRALLTPAACE +EMLVILRRQHYTDHITRAGVEPVITVASKSGSIR-GTRNDVALVESPNCR-YVIAMMSRD +CKDRDNEAAVLLAEVSALVYQHf +>[subseq from] Uncharacterized protein n=1 Tax=Anaerofilum sp. An201 TaxID=1965588 RepID=A0A1Y4HEK8_9FIRM +---LYGRICSILEGIPGRLSVAVRWLDSGETL-LLHETLPFVAASVIKLPVMIAAFAARE +AGTLDFSAPVPLRAEDKLPSCGVLKAMHDGLPTVADLCHLMITVSDNTAANRMIRLV-GI +DAVNGCMAQYGARDSRLRRLLFDADAS-AKGIENTVTASDMLLLLQKLYAGEIVSPEASA +EMLDILADQRL-NGKMPFWLPPGTRCAHKTGEDD-GITHDVGIVYAA--RPFAGCFLSQH +TD--PPRFIRAIQDITRLLYE-- +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. C10 TaxID=2600577 RepID=A0A5C8K2T2_9ACTN +-------FAELFRVAGVTGWLFAADLDSGREV-GHDPDEWLPMASMFKVALMVELCRQAD +AGLLDLTGRVTVTAADRAAPTGLSAMHDDVTMSLRDLAYLMIAVSDNTAADALLSRV-GM +DAVNAMLEGFGFEATRVLMTAGETNGALDPARTNRSTPRELARLFGLIWHDEAASPESCA +WMRTVLNLQVW-PHRLAAGFPDDVAVSGKTGTLPT-MRGEAGVVEYPDGGRYAVAVITRA +FSLNHPRADAVIGTAARMAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium MedPE-SWsnd-G1 TaxID=1860094 RepID=A0A1J5MA93_9BACT +-qDFKNQIQNDLKNIKGNTALVLFDLNQNKTLlNINSKAEFHAASTMKVPVMIEVFKQAR +EGKFSIKDSILVKNESIVDGSAYQYKMVDKKVTIEKLVYDMITVSSNLATNILIDMV-DA +KKVTETMRSLGADKIEVLRGVEDQK-AYDKGLSNSTTANDLVQIFKGIASNAAGSESECN +NMLSILKDQKY-NDLIPKYYPKNVTVAHKTGSIT-GVHHDAGIIYLPNGNSYVLVILSKN +LE-DFDRGTDALAKISKKILD-- +>[subseq from] serine hydrolase n=1 Tax=Fictibacillus gelatini TaxID=225985 RepID=UPI000427F90F +------HLQEVATGICGKMSIVLEI--ENLQI-SINGDDPFPSASLIKIPIMMEAFRQAQ +IGMLDLDETYRVPSEAPVGGMGVIQHRPEIELSIHDLITLMIIVSDNTATNLLIDLV-GM +EAVNKLSSDLGCNQTLLARKMMDVTAQ-KNGKDNWTSAYDIVKFLKEIDQGKLLTSKQRT +NALKTLRQQQF-HSKLPALISEETYVAHKTGELP-GTEHDAGIIQANGK-RAYIAVLTTD +LDNN-ITGQKAIAQIGKLVFDH- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8J4H7_9BACT +------------------------------------------------------------ +------EQLIQVTTNDFVTHSPIRDAHPLGALSVSNLLRQMVSESDGTACDVLLRLLNGP +PSVDHYLRELGLTNVVVATSEKEMGQDELAQYRNWATPEGLTGLLRILHEGRGLSVPGRE +MLLRFLTETSTGPRRIRGLLPTGTRVAHKTGSSRTRATNDAGIVTLPDGRHMAIVVFVSD +SAADEVTRDAVIAKISRAAWDYw +>[subseq from] serine hydrolase n=1 Tax=Deinococcus pimensis TaxID=309888 RepID=UPI0012FC2D55 +------------AGHPGHVSVVVRDLTSGEVLrEHDPDRVYPAASTIKIALLVAALRLVD +AGAAHLDERPVMDAGDRVGGDGVLKELVAGLPTLRDLLTLMIVVSDNTATNMVIDRV-GV +DTVNAFLREAGLSGTELLGKLPERQSAQRAGERNRTTARDLAELLLRLARGELLSRSSTE +VALDILSRQQH-QNILTRHLPRDWRVASKHGELR-GVHHDVGVVWSP--RPVVLAILSEG +GLDP------------------- +>[subseq from] Uncharacterized protein n=2 Tax=Bacillus sporothermodurans TaxID=46224 RepID=A0A2T6EVD7_9BACI +--SLRKQIDGIIEQTLGIVSIVVE-INEETII-SKNSKREMSSASLIKIPIIMAAFQQAE +LGKIDLEEKIEVKPEHKVGGSGVIQYLTEGTLSVKDLLTLMIIVSDNTATNMMIDLV-GQ +ETINYFNKQIGCNHTRLERRLMDYVAR-DMGLDNVTSASDMVIFLKEIVENQFLTSKSTY +EILNILSGQQF-QDKLPAMMDDHVFVANKTGEIP-GVEHDVAIIRHNDD-QVFMAVLIDQ +LE-NQYEGKQIIARTGKAVYDY- +>[subseq from] serine hydrolase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=UPI0002D1ABA6 +--SLEEEVTEKIRRLPGKTGFYYENLVTGERA-AYHEDERMMAASVIKLFVMTEAFVRFE +EGTLSTDRIIRMKREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTATNVLIDLL-GI +EEINRTIRRMGYRDTVLQRKMYDTEKS-KRGIQNYITAAETGRLLREMYQGRLVSRQASE +KMISILKNQQL-CSKIPQALPEEPEIAHKTGEDC-GITHDVGIVYAKQ--P-FIVCYCGN +DT-DTPAYERVMAETSLWLY--- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI00142D4197 +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPDTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A3C2DN38_PSESP +---FLAHIARVDDQTPGRLGVYVKDMETGIST-SYHGEEPWYLASTVKVPVAITVMRRIE +EGALSLDTGVPLLASDYVDGAGATNGFVPNTHSVRFLMEQMLIHSDNTASDMLIRLV-GL +ERVNAVTRELVPQGFGPITTLADVRRRYYATPYNSATLKAYGDLLSALDAGTALNPDSTR +YLLGVMRRAETGARRIKAGLPPTVGFAHKTGTQR-ARICDAGLVDQPTASRRLLIVACVR +EAASTAKAERALRGTGEAVT--- +>[subseq from] hypothetical protein n=1 Tax=Sulfobacillus sp. hq2 TaxID=2039167 RepID=UPI001304CC79 +-------LREWIGTLPGIYGVFAKNLDTGKVF-TFNDTKVFPSASTIKVPILIELYRRVE +EEHLSLDHLLVMRREDQVGGSGVLKDLSPNTYSLRDLATLMITVSDNTATNLLIDFL-TI +EAVNITLRRLGVTHTELVRRLQRVPA-EPLDTVNHTTAQDMGLLMEKLATGTAISLAASE +QMVSLLKRCQG-PISITKLTAESIVIAHKTGSLAQ-ASHDVGIVYSPHLR-YVAALLSQG +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora taraxaci TaxID=1316803 RepID=A0A561W9F2_9ACTN +------------------SGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVSLDDGVLVTPEDIVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Carbepenem-hydrolyzing beta-lactamase KPC n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2P1BP16_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ +QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWE--------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Butyricimonas synergistica TaxID=544644 RepID=UPI0003728B1D +---LTDTISKIVSGYPGEIGVAVI-INNMDTV-TVNNKSIYPMMSVFKLHQAIAVCNDFD +RKGLSLDSLMCIKRDELDPWSPMMKEHSEPVLTVKDLLRYTLIQSDNNASNIMFKELVSV +ARTDSFIATIPRTSFRIAYTEGEMSVDHDKAYSNYTSPLGAAMLMNRLFTDSLVSREKQC +FMMNTLEECITGKDRIVAPLKEGITIAHKTGSGYNGAHNDVAYIRLPNNVCYSLAVFVKD +FKGNEAQASKAVACVSAIVYA-- +>[subseq from] Serine hydrolase n=1 Tax=Salegentibacter salinarum TaxID=447422 RepID=A0A2N0TQX1_9FLAO +-eKLQHQIDSIFKRTQGDFAIAFKDLSTENHSiFINHHEDFHAASTMKTPVMIEVFKQAS +EEKFSLQDSLLIKNESIVDGSSYSYVQIGQKRSIEDLVTDMIIYSSNLATNIVIELV-DA +KNVNKTMRNLGALNINVLRGVEDMK-AYEAGLSNSTTAYDLMLIFEALANGNVVNPEADK +KMLEILRQQKH-NDLIPHLLPEDLNIANKTGWIT-GVHHDSALIELPDGTKYILVLLSKN +MK-DMDAGTKMLTEVSKMIYDH- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas songnenensis TaxID=1176259 RepID=UPI000EFDA22E +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGRLFEQVGQAIS--- +>[subseq from] Uncharacterized protein n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A645AQ81_9ZZZZ +---LKDDILKCFDRMEAKVSIVLKDLLKEEVMlELDAARVVPSASTIKILIMIEALKQVM +EGRISLDEMVFVKPYERVDFSIISE--LGAAYSIRDLITLMIIISDNTATNVLIDIL-GY +DNINDQAEKMQLKGTVLQRKMMDFEAA-RQGRQNLTTARDMAYMMEALYKESILDRNMCD +LALNILKRQKH-KDLLTRYIAEDIVVAHKSGDLEN-LNHDIGIFYLTDT-VYLLGVFVTE +AE-SNVSAKHIIGKVSEAAYKYf +>[subseq from] Uncharacterized protein n=1 Tax=Pseudomonas fulva TaxID=47880 RepID=A0A0D0KK47_9PSED +---LLERLQTLAAKQDGELGVYVKDLHSNLAV-TLHAEELWYMASGIKVPVAIAVLRGVE +RGDWNLDSRLTLAADDFVDGAGSTNQYGPGELSVGFLLEQMIIYSDNTATDRLIRLA-GL +DAVNALVGELVSEGFEPITTLGDVRRNYYRSNLNAARLSAYGELLERLADGQALGAEQTR +YLLGVMGRVKTGSKRIVAGLPDDARFAHKTGTQRE-RICDSGLIETPARQPVLIVACVQG +E-PSLAKAERSLRQVGEALT--- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8PL81_9BACT +------------------------------------------------------------ +-----------VTKKDFVRNSPIRDEYPNGTLTVSELLRYAISKSDGTASDVLMRVAGGA +DAVQSYLGELKINEMVIANTEKEIGQDWETQYRNWSSPEAAVALLRALHERRGLSESGQM +LLLKFMIESTPGPKRLKGLLPAGTIIAHKTGTSGTAATNDIGIITLPNGKHLAIAVFVAD +SAADEASREGVIAKIARAVWDTw +>[subseq from] Serine hydrolase n=1 Tax=Anaerolineae bacterium TaxID=2052143 RepID=A0A3D0RNT1_9CHLR +------QLEKFIAQFNKTISISVSDLETNQEI-NINADVLMHPASTMKVPVMMEVFRQTQ +VGNFSLDDQIEIYNSSIVDGSDFDYSRIGEKETIRELNRLMIVWSSNLATNILMDKV-GT +KPIDDFIKELGIKNVNVMRLIEDKQ-AYRLNINNTFSARGTTHMMRLIAEGKVISQEASD +EMIKVMLGQEF-NESIPALLPKDVKVAHKTGWTGE-FFHDTGIVFPSNRKPYAITLFTNG +FPDDESQAHNCMAEISKLVYE-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas songnenensis TaxID=1176259 RepID=A0A482UH65_9PSED +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGRLFEQVGQAIS--- +>[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus benefaciens TaxID=453960 RepID=A0A2T2WQE7_9FIRM +------ALQELIDSLPGRYAVFAKNLVNNKTF-DYHANETFPSASVIKIPILMELYRRVE +ESHLSLDHLLLMGKEDQVGGSGVLKDLTPATYSLRDLATLMITVSDNTATNLLIDYL-GV +DNINATIRHLGAQNTELIRKLQRVPAE-QHSRVNHTCAYDMALLMEKLATGTATSLAVSE +EMVSLLSRCQGPVSIAKAPADNDVLIAHKTGSLSE-ACHDVGIVYSPQIN-YIAAILSEG +A---------------------- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A2U8SYZ3_PSEST +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGRLFKQVGQAIS--- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Marinimicrobia bacterium MT.SAG.2 TaxID=2552983 RepID=A0A4Y8I9N8_9BACT +------------APSGAEVSVAYENLQTDIKM-FINAKKQMHAASTYKTALMVEVYKQAA +EGKISLTDSIDVINSSIVDNSEYAYELIGKRASYYDLTYQMITVSSNLATNLLINEV-GA +KNIMKTLKSIGIKEMQVLRGVEDLK-AYELGLNNTTNAEDILRLMIAIAKDEVVSPSACA +EMRKILLAQVH-NSKIPAKLPKEVKVAHKTGSITK-IDHDVAIIYPPKGPVYALVVLTRG +IK-EHKDAEELIADISKIVYD-- +>[subseq from] Uncharacterized protein n=2 Tax=Cyanobacteria/Melainabacteria group TaxID=1798711 RepID=A0A349HYE1_9CYAN +---LQSELTNLMAQYTIQPSVYVWDYETGNYV-DINASKVYATASIIKIPVLIDLFKSIE +AGQVSLEETMPLTEYFRTEGSGSLQFKAAMSYTIDKLAELMITESDNSATNMLMTRVGSM +VDVNQAIRDWGLKNTEVQTWLPDYAGT------NHTTAREMGRMLYNIDEDKFLTQESRA +KILNYMGHVHN-NRLIHAGLGAGAVFLHKTGDIGT-MLGDAGIVIAPNGKKYIVVILANR +PH-NAIEGKDFIVHASELIYNY- +>[subseq from] Beta-lactamase n=1 Tax=Brachyspira sp. CAG:484 TaxID=1262759 RepID=R5HJN5_9SPIR +-------IKNLMTAYSIHPSVYVWDYDTGHYA-DINASELFSAASIIKIPVLLQLFRSVD +LNQVSLYDEMTLTEYYRSEGSGGLQFKAANSYSLDTLARVMITDSDNTATNMIMSKIGSM +TDVNQGIRDWGLKQTHVKTWLPDLQGT------NHTTARDLGVMLYNIENPKFLSMSSRE +RIFDYMGHVKN-NRLIQAGLGPGASFLHKTGDIGK-MLGDAGIVYTPNGKKYIVVILANR +PYN-SPAGKDFIVRASEIIYNY- +>[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus sp. TaxID=33949 RepID=A0A357A2I6_9FIRM +------ALQELIDSLPGRYAVFAKNLVNNKTF-DYHANETFPSASVIKIPILMELYRRVE +ESHLSLDHLLLMGKEDQVGGSGVLKDLTPATYSLRDLATLMITVSDNTATNLLIDYL-GV +DNINATIRHLGAQNTELIRKLQRVPAE-QHSRVNHTCAYDMALLMEKLATGTATSLAVSE +EMVSLLSRCQGPVSIAKAPADNDVLIAHKTGSLSE-ACHDVGIVYSPQIN-YIAAILSEG +A---------------------- +>[subseq from] serine hydrolase n=1 Tax=Gelidibacter mesophilus TaxID=169050 RepID=UPI000415AE3B +-eDLEKTIQNQIDSIEGTVAVAFYSLSEPKDSlLINADEKFHAASTMKVPVMIELFKQAS +EGKLDLKDSILLKNESIVDGSLYSYSQIGTKVALWDLMHSMITVSSNLATNVLIELV-DA +KKVTASMRRLGAKDIEVLRGVEDQK-AYDKGLSNSTTAKDLMVIMEAIANKTAGNQKDCD +AMIAILKDQQH-NDIIPLYLPKEIEVAHKTGSIT-GVHHDAAIVYLPDGRAYILVLLSKN +LK-DFDQGTDQLANISKTIYDY- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI00124AF7A9 +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPDTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DD5B7F2 +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPDTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodothermaeota bacterium MED-G16 TaxID=1986238 RepID=A0A2A5XJ05_9BACT +-pSLQNNIEKIIKSEKGKFAIAFKNLEDGQVI-LINEMEEFHAASTMKTPVMIEAFKKSF +ENKISLDDTILVKNESIVDGSLFKYERIGGHLSLRELIYEMITISSNFATNLVIDYI-GH +EDINKTMRDLGAKDINVLRGVEDIK-AYNKGLNNTTTALDLLKIYENLALGRVINTKLSQ +KMVDILKDQKY-DDIIPKYLPKEIEIAHKDGWVS-GTRHDSGIVFINDEKKYVLVLLSKN +LE-DEIKGADILAKVSLEIYN-- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium sp. CAG:813 TaxID=1262843 RepID=R7MIN3_9CLOT +---LQSELTNLMAQYTIQPSVYVWDYETGNYV-DINASKVYATASIIKIPVLIDLFKSIE +AGQVSLEETMPLTEYFRTEGSGSLQFKAAMSYTIDKLAELMITESDNSATNMLMTRIGSM +VDVNQAIRDWGLKNTEVQTWLPDYAGT------NHTTAREMGRMLYNIDEDKFLTQESRA +KILNYMGHVHN-NRLIHAGLGAGAVFLHKTGDIGT-MLGDAGIVIAPNGKKYIVVILANR +PH-NAIEGKDFIVHASELIYNY- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI00132F7441 +---VEGTIKDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFIMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKELIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] Cephalosporinase n=1 Tax=Bacteroides sp. CAG:927 TaxID=1262753 RepID=R5BAE2_9BACE +--ALQSRLQEYISGKNARIGVAVIY--DQDTV-SVNGYDEFPMMSVFKFPLALAVAQWAE +TNGVVLSDSISFGPDALRRYSPMLDKYGPSLLSIQELLKWSLMESDNNAADIILHLIGGP +EAATNLMKQAGCEAITIGASENDLHSRPDLILLNKATPIAMAALFHRFNTEIRHRSSSFA +EIATMLEQCRTGADRLAVLLPAKAVIGHKTGTGFTTALNDCGYVNLPDGRHYSIAVFIAD +SPYSTQATAKIIADISSIVL--- +>[subseq from] serine hydrolase n=1 Tax=Larkinella soli TaxID=1770527 RepID=UPI000FFBFB84 +-----ESLNAYLQKLTVRVSLAVESLSDSTVGyFHQADEAVPSASVIKIPILIEAMEWVK +AGRINPDENHILLDSEKTGGSGILATYPHRTVSYRDVMTLMMTHSDNTATNLLIAEI-GM +EAVNARMRQLGLTQSRLNRVMMDTLAA-RQGRENRVSCREMNLLLKKIYRRQVATPALCD +EMLDILKRNED-TLTIRRFLPRSTVIAHKTGGLAY-VRGDAGIVFAP--RPFLFTAFVQG +TNT--GDAERIIGELAALCFKQf +>[subseq from] serine hydrolase n=1 Tax=Bacillus dielmoensis TaxID=1347369 RepID=UPI0005A6580E +---LEVKIAEELIEFKGRIGLAIEI--GNVRL-DFNSQDVFPSASVIKVPILIEGLRQCD +AGLINLDELIRIEN--RAGGSGVLESLSSEALTLLDLLTLMITVSDNTATNMLIDRL-GI +ESINRTITKIGMTGTVLNRKMMDFEAK-ERGLDNKTSAADMVCCLKAMNEGSILSETSRS +LALKIMHAQQF-QDKLPAMMDDKIYVANKTGSLPK-VENDCAIMAYNDQT-AYVAILTDE +LDEP-YTARQVISRIGKYIYDY- +>[subseq from] serine hydrolase n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=UPI0007EFFE7C +----ERQVERRILAAPADVAVFFRLLGGEAEW-SYQPDVTFHAASTMKVPVMIELFHQTH +QGQLTLDDPLPIHNESLVDGSAFYYSSEGQTRTLRQLCELMITMSSNLATNLLIKKL-GI +ENIRATVHLLGADGMNVLRGVED-NKAYDLGLNNTTTARALAILLTAIAEGKVVDPDASR +QMVEILKRQHI-NDGIPSGLDPTIPVAHKTGTLK-AIHHDAAIVYG--SQPFVLVILVRG +MA-DSKDSSALMADITRAFYR-- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. CV4 TaxID=2478711 RepID=A0A3L7BSG0_9ACTN +------------------SGVTVRDLSGDQQI-AVNGALRPKAASVIKLWILVELLRRVD +CGQVSLDDGVLVTPADVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNIAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILSPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSE-TAVAFLTAG +PM---ETGDETVRRMARTVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3A0AJK3_9CHLR +-------------GTGGIVGMCVVA-PNGERW-SHNGDRQFGAASTVKIPLMVEIFRGID +RGERTLADPYVLRDEDRAAGSGVMLHMSAGDLTLWDLLYLTISISDNTATNLLIRMA-GM +DAVNATMRELGMPNSVLAREMKGR-PAIEGEGENWATANDYANVMLSILNGTAASADSCA +KMLDLLSKQQN-ARRIARYLPSDIRWGSKTGSVT-GVTNDVGFVTSSAGT-VVIAVFCEN +FP-DQHVGEYVIGALARAAF--- +>[subseq from] serine hydrolase n=1 Tax=Cyclobacterium xiamenense TaxID=1297121 RepID=UPI0012B7E973 +--ALEDDIRSLMQATEGDFALAFRILDSGRQL-LINETEVFHAASTMKTPVMIELFKQAA +AGEFSLQDSILIVNESIVDGSTFRYERIGEKASLYELMYQMIIKSSNLATNILIDRV-GA +KNVTQTMRGLGAEDIQVLRGVEDLKA-FDAGLSNSTTALDMLQIMEAIARGKV---EGSR +EMVKILSDQYF-KDLIPNLLPADVKIAHKTGSIT-GVQHDTAILELPNGTRYVLVILSKN +LT-DVPAGKEAIARMSRLIYDY- +>[subseq from] Uncharacterized protein n=1 Tax=candidate division KSB1 bacterium 4572_119 TaxID=1971636 RepID=A0A1W9SFP6_9BACT +---FETEIRRLEKYTGGRIGVMAKNLGSGEIV-SYRADEKFPTASVIKVPVMVEYFYQVK +EGKLNPTQKIVLADSNKWGGSGLFQYFQGTTQQLIDAVLMMITISDNTATNMVIDVLGKL +EAVNERMKKLGLKNTRLLNKLMSWETDSPESIRGVSTPADMVNLLEQMATFQLVDSTSSK +GMISILEKQEY-NTIIPRLLPPGLRVAHKSGSVT-GVRNDVGLIHSSKA-NIALAIFIEQ +SLKSGPENEAAAAKISRLVWNYf +>[subseq from] Uncharacterized protein n=1 Tax=Anaerolineaceae bacterium TaxID=2024896 RepID=A0A2E1AJT3_9CHLR +--TLKDDIQAVLTQANIDAGVAVWHIESGEQT-DVNGDVPYPMASTFKIPILATVFTQIK +EGKLSLETRYKLTTEVKSPGSGILPYFQEGLPTLLDMLTLMIIISDNTATDMIVDILGGP +DVVESYMHQLGLTNIYFKMNCKDLIAFSLMPDNDIATANDMNKLLHMIYTGELFDGELRE +TALGILFKQQF-NVRMTRFFPPSVKVAHKTGTIG-GIRNDSGIIYINDDTHVILTLFVEW +----------------------- +>[subseq from] Serine hydrolase n=2 Tax=Falsibacillus sp. GY 10110 TaxID=2478915 RepID=A0A3L7JVM8_9BACI +-nDLEREIMGIEAGCAGRIGLFISA-DEGQIM--TNEGESFPSASLIKLPIILEAFRQAD +ARKLDLNERIMVHPEEKVGGAGVLPALSDNIFNIIDLMTLMIIVSDNTATNLVIDKI-GM +KSINQLISCLDLKETLLSRKMMDFD-AIHQGRNNYTSPRDIVTLLKEIHHGEMLNEKSRQ +QIIGIMRQQQF-TDKLPALVEDKIRIANKTGELD-GVDHDCAIFEYGGK-TVFAAVLIDG +LV-DKVSGKYTMNQIGCAITDY- +>[subseq from] Putative Beta-lactamase n=1 Tax=mine drainage metagenome TaxID=410659 RepID=E6Q6H2_9ZZZZ +---LRDSLRSLARSSDANVGIAVEDLATGAVT-GYNLNRSMPAASTIKIPVMVEVFRQMA +RGRFTLTHVMHLREVDRDYGSGDLAYPLGTPVTVKRLLSEMIDVSDNTAANMLIRLV-GR +QRINAAMQAYGCHHTYLRTAIRTNVSSV--ETNLRTTPLDMLTLLVRMARGKLVDTWSSH +AMLEILAHQEI-DTLLPEPLPDGTTIAHKTGSLHD-VMADVGIVYEPGA-PFAIAAMTSG +LP-DPQLGRDIVRQAS------- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00128F231F +------------------------------------------------------------ +--------KVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQ----------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=A0A328NH74_9ACTN +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas stutzeri NF13 TaxID=1212548 RepID=M2VGZ3_PSEST +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEGAWYLASTVKVPIAIAVMRRIE +QGDFTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +EQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGIALGPASTE +YLLSVMRRVETGVRRIKAGLPSGTGFAHKTGSQR-ARICDAGLVDQPGAQRLIIVACVRG +VA-STAQAERALHGTGEAVA--- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7B6A6B +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARKLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] serine hydrolase n=1 Tax=Nodosilinea nodulosa TaxID=416001 RepID=UPI00031A7510 +-----------------------------------GGNQVFPAASTIKLTILIAFYQDLD +AGKVSLNDTLVLRRDLLTGGSGAMQYEPIGSYSAKEVLKRMITISDNTATNLIIDHLGGI +DCLNARFRSWGLQHTVMHNLLADLRGT------NTTSAEDMVSLLAQVVEENLLSSQSQD +QVLNLLRHTTI-RSLLPAGLGPGANIADKTGDIGF-LIGDAGLIIMPTGKQYLAGIFVTC +PYND-VRGRNFIQEVSRTTYTY- +>[subseq from] serine hydrolase n=1 Tax=Caulobacter henricii TaxID=69395 RepID=UPI0005533C5F +-qTMTAQFQPIADRVPGGLGVAVEDLGTGQVI-SFNGDRRFPLQGAVVAPLAVAVMAQVE +AGRLRLDDVVLIEDVDLSPPSAVADAWPGRNYTVQDLLERAVVQGDTTAADVLMKRVGGP +GAVTAWLQGRKVHDLDIARYQRQLLPASLADPRDTATPLGALRLLEALNQAELVGPDSRR +LLGRITSQAQGGSGRLRAALPDGARLAHAPATARTDLVGDIGVYTLKDGRKFAVVAFVSG +SALPVAAQEKAIADVGRVVIK-- +>[subseq from] serine hydrolase n=1 Tax=Caulobacter henricii TaxID=69395 RepID=UPI00055255A3 +-qTMTAQFQPIADRVPGGLGVAVEDLGTGQVI-SFNGDRRFPLQGAVVAPLAVAVMAQVE +AGRLRLDDVVLIEDVDLSPPSAVADAWPGRNYTVQDLLERAVVQGDTTAADVLMKRVGGP +GAVTAWLQGRKVHDLDIARYQRQLLPASLADPRDTATPLGALRLLEALNQAELVGPDSRR +LLGRITSQAQGGSGRLRAALPDGARLAHAPATARTDLVGDIGVYTLKDGRKFAVVAFVSG +SALPVAAQEKAIADVGRVVIK-- +>[subseq from] serine hydrolase n=1 Tax=Pyxidicoccus sp. CA032A TaxID=2709663 RepID=UPI0013DCB382 +---LREGVDAAARDFDGELALYVRDLSTGEEY-ALNASTPMYLSSAIKVAVMLEVLRQVD +AGTLALDTPIAFEPDDARDMHPMAKVPPGTALTVATLLEHMMVHSDNAAADLLIGKV-GI +DHVNAGLERRGVHFGPLVSLLEDRHHAYYAEGTNSASMRELGQLLEQVARCEGLSPATCE +HAKSLMRSCDTGRARIRAGLPGTATWAHKTGTQHR-RACDVGILELQPGHPIIVAACTRG +FR-RVTEAEHLLARIGRTLTKAf +>[subseq from] Beta-lactamase class A n=1 Tax=Hungatella effluvii TaxID=1096246 RepID=A0A2V3XVZ7_9CLOT +--SLEEEVTEKIRRLPGKTGFYYENLVTGERA-AHHEDERMMAASVIKLFVMTEAFVRFE +EGTLSSDRIIRMKREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTATNVLIDLL-GI +EEINRTIRRMGYRDTVLQRKMYDTEKS-KQGIQNYITAAETGRLLREMYQGRLVSRQASE +KMISILKNQQL-CSKIPQALPEEPEIAHKTGEDC-GITHDVGIVYAKQ--P-FIVCYCGN +DT-DTPAYERVMAETSLWLY--- +>[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus sp. hq2 TaxID=2039167 RepID=A0A2S3QDN6_9FIRM +-------LREWIGTLPGIYGVFAKNLDTGKVF-TFNDTKVFPSASTIKVPILIELYRRVE +EEHLSLDHLLVMRREDQVGGSGVLKDLSPNTYSLRDLATLMITVSDNTATNLLIDFL-TI +EAVNITLRRLGVTHTELVRRLQRVPA-EPLDTVNHTTAQDMGLLMEKLATGTAISLAASE +QMVSLLKRCQG-PISITKLTAESIVIAHKTGSLAQ-ASHDVGIVYSPHLR-YVAALLSQG +----------------------- +>[subseq from] Serine hydrolase n=2 Tax=Microbispora sp. GKU 823 TaxID=1652100 RepID=A0A1V4EGH3_9ACTN +--------ERVFRSAGVTGWLHAVDIDDGREV-GLRADEPVVLASVFKVPLLLELHRQAE +RGLLDLSERVRVPAEDRTAGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLSRV-GR +EAVNTLLDGLGLTATRVVQNCRDMLTALDPALGNRSTPREMTRLLAMIWRDEAAGAASCA +AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +LSQNQPRADAAIGAAARMAIDQ- +>[subseq from] Uncharacterized protein n=1 Tax=Micromonospora ureilytica TaxID=709868 RepID=A0A3N9YAE7_9ACTN +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVALDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Beta-lactamase n=1 Tax=Luteimonas sp. 9C TaxID=2653148 RepID=A0A653V491_9GAMM +------------------------------------------------------------ +---------------------------------------------DNMAIVRLRNADAGE +PRLQALAEELVVPRADLDATLESVFDAYYRGDRNTATLAAFATVLDRLAAGELLSSDSTR +RMLDHMRAISTGDRRISAGLPPGTDFAQKTGTQLR-RACNVGVIDPEARNGATLVLACAE +DFDDIAQAETAFQGLGRALAD-- +>[subseq from] Serine hydrolase n=1 Tax=Caldilineaceae bacterium SB0664_bin_27 TaxID=2605260 RepID=A0A6B0Z0Z8_9CHLR +--SLESDIRNITANSGAEMAVSALHLESGQRF-DVDAERVYPLCSVLKIPVLVEAFRQIE +EGLFTLDDRWQLTTAEKNLPSGILVFFDDGLPTVRDLLTLMIIISDNTATDMVMHRL-GE +GSVTRTMHDLGLTDIHVPLTIRELFDYSLGPDNDTGTPAALTELLARIWRGETVSRAACD +TMLEILLKQQL-NDRLPRYLPPGTPCAHKTGTLP-GIRNDSGIIYAGESDHVAVTVFSRW +DDEA------------------- +>[subseq from] serine hydrolase n=1 Tax=Prevotella sp. RM4 TaxID=1200547 RepID=UPI00051B1A3F +---------------------------GGSVS-GINKDERFAMHSVMKFPQALYVADYLS +RKGLALDDTIVVDKADLMQWSPMLKQFERKMFSYAQLLELSLAQSDNNACELLFKHCGKP +KAVEKYIRKLGFYDIHVRMTEEQMHNNPAKAIENSSTPAEMVRLFEWLYYYKD-DNQYLT +FIWKAMADCSTGLKRIPAAIPADARIVHKTGTGFLQDMNDAGIILMPDGSHVIIAVFTTN +SP-----SEAVIADIAKQLLE-- +>[subseq from] Uncharacterized protein n=1 Tax=bacterium SCN 62-11 TaxID=1660156 RepID=A0A1E4FZ27_9BACT +------RILTQLRQMPGEIAAYYQDLHTGRSW-GWNAEADFPAASVIKVPILLAVLQANQ +AGLLSLDQRVSVEFRHHVGGAGVLFEHDGAEMTVMDLCRLMIVVSDNVASNLLLDLL-PD +GAMAGLFRGLEMHRSLLGRRFMEQPR---PGHDNRTSAFDMGLCMAALARGEILDRSHTN +QALSILRRQQF-REKIPLMLPPELSVAHKTGELD-GVRHDVAVVEVPER-PYVLSLLTQR +GGHS-WDVDRALAELSLSVYH-- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3MR35_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +GRIDALRNAMGMKATDLKRTIDDAYDRYYRAGLNAATLEGYGAMLEKLVRGELLSPASTQ +RLFKEMKIDIFTNYRLQAGLPRSVKFVHKTGTQYR-RACHAGVIEPQNGAHAIVVATCAA +DIDEQKAAGVVFERIGRAISQ-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI0011BF8304 +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas seleniipraecipitans TaxID=640205 RepID=UPI0008AA45CA +---LLARLQSIAAKQDGELGVYVKDLHSNLAV-TLHAEELWYMASGIKVPVAITVLRGVE +RGDWNLDTRLTLAADDFVDGAGSTNQYGPGAVSVRALLEQMIIYSDNTATDRLIRLV-GI +DAVNQLVSELVPEGFEPITSLADVRRRYYSSNLNAARLTAFGKLLERLAYGEALGAEQTD +YLLGVMSRVKTGSKRIIAGLPKDARYAHKTGTQR-ARICDSGLIETSGTAEPVLVVACVR +GELSLAKAERTLRQVGEAL---- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. CV4 TaxID=2478711 RepID=UPI0011C46E36 +------------------SGVTVRDLSGDQQI-AVNGALRPKAASVIKLWILVELLRRVD +CGQVSLDDGVLVTPADVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNIAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILSPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSE-TAVAFLTAG +PM---ETGDETVRRMARTVYD-- +>[subseq from] serine hydrolase n=1 Tax=Larkinella soli TaxID=1770527 RepID=UPI000FFB79B6 +----REAVIRELENVPGTFAVAFRDLRTGEEL-LLRDREVFHAASMMKLPVMIEVYRQAA +EKRLSLSDSLLIDNASIVDGSPFRYGRIGGKRTLSSLVYDMIILSSNLATNLVIERV-GA +RNVTATARRLGARDLQVLRGVEDGKA-FAKGLNNTVTAFDLMQLLTVIAEGRAVGPEASR +AMIDILLDQRF-NTILPANLPKDVRVAHKTGWIT-GVLHDGGIVFLPDGRRYVLVLLSKN +VK-DEPAARQTLAKVSELVYRH- +>[subseq from] Serine hydrolase n=1 Tax=Emticicia sp. C21 TaxID=2302915 RepID=A0A372F8I2_9BACT +---------------SIKVSMSVESVSGDKYF-TLRPDVTVPAASVIKVPILMELMEQVK +AKKINLNAIHILQASDKAGSSIIADKPAGTQLTIRELAQEMIHSSDNTATNILIKEV-GM +EDVNQNLMRLGSTKTKLNRIMLDTLA-VKQGRQNWVNALEINDLLRKIYNKKVATPALCD +EMIVILKNCRD-KTTIPRNLPEDLAIAHKTGELSY-VRGDAAIVYTK--QPFIISIFVEG +FK-DLSQAEQIIGDLAEICWE-- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI00026D67F3 +---FLAHIARVDEQTPGRLGVYVKDMETGIST-SYHGEEPWYLASTVKVPVAITVMRRIE +EGALSLDTGVPLLASDYVDGAGATNGFAPNTHSVRFLMEQMLIHSDNTASDMLIRLV-GL +ERVNAVTRELVPEGFGPITTLADVRRRYYATPYNSATLKAYGDLLSALDAGTALNPDSTR +YLLGVMRRAETGARRIKAGLPPTVGFAHKTGTQR-ARICDAGLVDQPTASRRLLIVACVR +EAASTAKAERALRGTGEAVT--- +>[subseq from] serine hydrolase n=1 Tax=Rudanella lutea TaxID=451374 RepID=UPI0012FA68B0 +---------------SVRVSVALETLADSSVRlYHRADERVPSASLIKVPIMVEAMVAEI +EGRINLDEIHILLDSEKVGGSGVLKDYPNRSISYRDLVRLMITSSDNTATNILIGDL-SP +EAINARMRTLGLTQTGLNRVMMDTLAA-RQGRENIVTAREMNRLLTLIYRRQVATPALCE +QMLDFLKANED-SLTIPSRLPRQLVVAHKTGTLSY-VRADMGIVYAP--RPFVLSVIVEG +AGSD-IAAETVIAQIARLAYS-- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=A0A5D4TWD2_9BACI +---LEERILDAIDKCKGRISVAI-DLPS-HSI-QINSDTPYSAASLIKIPILLECFRQSE +HGKIDLDETVMVPKEYRVGGAGVLSTLSERILTVEDLLTLMIIVSDNTATNLIIDRL-GS +EAINNLCNSLALKHTKLSRKMMDFQA-MKQGYDNFTSASDIITCLRSLDQGTLFSQKSRD +KMLYILHQQQF-NTKLPARMDDKIYIANKTGELP-GVEHDCAIVRSEEKT-AYIVVLIDE +LDEN-ESARDTIAEIGKLLHDY- +>[subseq from] Class A beta-lactamase n=1 Tax=Duncaniella sp. TLL-A3 TaxID=2530391 RepID=A0A4Z0V6L8_9BACT +-dALRDSISAIISDVTGEIGVAAI-IDSKDTV-TVNDIDKYALMSVFKMHQAVAICHSFD +LKGTPLDTIIEIDRTSLNPWSPMLKEHDNEHTPVSELLRYTLMQSDNNASNLMFDRLVSV +AETDSFIATIPRNSFRITERESDMQSDHSRSYNNHSSPLGVAMLVERLFTDSILSHEKQE +FICETMRSCSTGTDRIAAPLKDGITIAHKTGSGYINAHNDAAYITLPDGTSYTLVILVKD +FAGNEKQAAAIMARISDTVYQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Thermoactinomyces sp. AS95 TaxID=1811386 RepID=A0A151Z1X9_9BACL +-qKLSGSLDAWKKKSSGIWGIWMEDLNTGEKW-IWNEKQPFVAASMIKVPVMVAVYRAHA +LGKLCLSDRIELRREDRVGGSGVLQHLSYGTFTIQDLVTLMIIQSDNTATNLLIDRL-GK +EFVQETLLALEMTDTVFINRLHIVPAG--SNKTNQITAKDMARCFRLLATGQAVSRDASR +KMVEILKKQQW-RNCLPGRLPPSWEMAHKTGWVNQ-TLHDGGILYIASH-SLILVVLSSG +LDH--HQAQREINHIGKWVYDAy +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F776C22 +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPKDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2D5BQ94_9BACT +-------------------CVAFHDLGTGQTL-LRDADVVIHAASTMKVAVMLEAYRQHE +AKRLDLDRPMRVHAKSILDGSPYTYAHLGASLPTRDLVQRMMVRSSNLATNILIEAL-DA +SSVQETLGSLGCRDMKVLRGVEDTP-AFEAGLNNVTTARDLMLLLHAIHEGRGVSAASRE +AMIATLRAQEF-NDLIPAGVGPGTPVAHKTGRIT-GIRHDAAIVYPKDRSPYVLVVLTRG +FD-DSEAAGAVIREISRTVWTH- +>[subseq from] serine hydrolase n=1 Tax=Runella limosa TaxID=370978 RepID=UPI000687B766 +hpALEQSLADYLAKLPVKVNYRVESLEGKRYA-SLGDDERVPSASIIKIPILVEVMEQVK +AQRFELTDYYTLQNADKVGGAGIFQEREGKAFTYEQLAHQMMVASDNTATNILIRKV-GR +EAVNERMKTLGFPNLQLNRVMMDTAA-VAKGIENYVNAAEINRLLSLIYQRKVATPALCD +LMVAFLLDNHD-TSTLPSLIPRQVGIAHKTGTLTY-IRGDAGIIFTK--KPFVISVFVRG +TEL--NRAETIIAEIGKISYE-- +>[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2D9TMW2_9BACT +-pSLQNNIEKIIKSEKGKFAVAFKNLEDGQVI-LINEMEEFHAASTMKTPVMIEAFKKSF +ENKISLDDTILIKNESIVDGSLFKYERIGGHLSLRELIYEMITISSNFATNLVIDYI-GH +EDINMTMRDLGAKDINVLRGVEDIK-AYNKGLNNTTTALDLLKIYENLALGRVINTKLSQ +KMVDILKDQKY-DDIIPKYLPKEIEIAHKDGWVS-GTRHDSGIVFINDEKKYVLVLLSKN +LE-DEIKGADILAKVSLEIYN-- +>[subseq from] Serine hydrolase n=1 Tax=Flavihumibacter sp. CACIAM 22H1 TaxID=1812911 RepID=A0A162QSX9_9BACT +---LDKAIRAEMSKHQAEFAIACKDLGTGQTY-FVAEKKSFHAASTMKTPVMMEAYKQAA +AGKFSLQDKITVKNSSIEDGSVFSYQLIGKELPISDILHRMITKSSNLATNIIIDLV-GA +KNVMTTMKEIGANQIQVLRGVEDKK-AFEAGKNNTTTAYDLMRVFEELGNGSFISKMACA +DMIRVLQDQYF-RNSIPAKLPREVKTATKSGSIVK-ITHDSGIVYLPDGRKYVVVLLSKG +IE-SQEEANAALAELSKLIYDE- +>[subseq from] Beta-lactamase domain-containing protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1R282_9ZZZZ +------------------------------------------------------------ +---------------------------------------------------------GGP +RELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] serine hydrolase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0011A60AC4 +------EMKQLLGDLKGKAGAAIEI--DNDCF-YFNHEEVFPSASVIKVPILIEALRQAE +SANIDVNESIQIRH--RVGGSGVLQALSDQVVTVKDLMTLMITVSDNTATNMMIDLL-GM +DAINTTIKNMGMQKTVLQRKMMDFS-AIERGLNNLTSPADIVTCLKVMNQGDFLTEKSRK +LALEIMHAQQFHD-KLSAMIPEAIFVAGKTGSLPQ-VENDCAIFKWGNKT-AYVAVLMDQ +LE-DSYSGRRVISKIGKYLYD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Odoribacter splanchnicus TaxID=28118 RepID=A0A413I971_9BACT +-------------------------------------------------FQAVTALKKME +AENIPLDKMVYIKQKEMLKYSPLRDKYPDQGISYRDIIKYTVSISDNNTCDWLIRFVGGI +DKVDSYIKSLGIKDMNFTETEESMHTDIMLCYNNWSTPLAIAQLLKKLHTENILTKEHFA +FLETAMLDCVSGKNKLIAGLPTDIKFGHKTGRSNRTSEGDAGVIYLPNGEKCYIVVLIKD +SRESDDDNAKIMADISNIVYRH- +>[subseq from] serine hydrolase n=1 Tax=Xanthomonas citri TaxID=346 RepID=UPI001243E25C +--DLERRLRSIDARYAGDIGVYVHHLGRDEAW-GFRADEAWYLASGVKVPVAIAVMREIE +QGWLTLDTRVALLDTDFVDGAGRTNAHRAGTLSISFLLEQMIIHSDNTATDVLIRVV-GL +GQVNAVAHELIAAQGVQITSLADVRRSYYATHVNSATLRDYGRMLASLQRGLAVDGDSTR +YLLDVMGRVQTGRQRIRAGLPAGASFAHKTGTQYR-RLCDSGIVTMPGGRPVQVVVAACV +RGSAGAAGERALRDIGAAVT--- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000775B61D +------------------------------------------------------------ +------------------------------------------------------------ +---EALARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] Beta-lactamase (Penicillinase)-like protein n=1 Tax=Ramlibacter tataouinensis (strain ATCC BAA-407 / DSM 14655 / LMG 21543 / TTB310) TaxID=365046 RepID=F5XZA3_RAMTT +------------------------------------------------------------ +----------------------------------------------------------GP +ERVEAVRRALDMPASALQATMAQAYDRFYENNLNHATLEGYGRMLERLVRGQLLSPRSTE +RLFGYMKFGRRGDYRLEGGIPRSEPIIHKTGTQYR-RACHMAVVNPQGGAKAIVVATCAA +DMDDVREAGGIFRQVGEAVS--- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium 50-39 TaxID=1895841 RepID=A0A1M3H548_9SPHI +----LQKIDSIFRSQPGSFALAFKDLSTGRQL-FLHEHETFHAASTMKTPVLVEIYRQAA +IHRLSLTDSIVLKNEFISISSAYQYRHVGEKRSINDLVYQMITVSSNFATNLLIARV-GQ +ANIGVTLHKLRLDELHVLRGVED-NKAYQKGLNNTVTAAGLAELFEKMAKGRLVSRQASK +DMIRILMDQHF-NDIIPAGLPAGTKVAHKTGWIK-GVHHDSGIVFLPDGKKYVLVLLSKD +LA-DDKAGANALAAISAIIYQY- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridia bacterium BRH_c25 TaxID=1734399 RepID=A0A101WEB2_9FIRM +----------NIKKLKGTVGVYYKSLTTGGTL-SFNEKKSIISASVIKVPVLVEAFHQME +IGTISKDEVMTLCDDDKMPCGALSYMHSGLEVTVEDLCKLMIILSDNTATNMLVKRL-RF +DNINGYMQELGLKNTFLGRLLFDMEAD-KKGSRNVISAKDIGMLFEMMWQGKLISSAASR +QMLDILKLQQF-SHKLPAKLDEEVAVAHKTGEDT-GITHDAGIIYAP--KPFILCVLSEG +TD--AVETNAFISGLA------- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DD79BBF +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. 03113 TaxID=2578211 RepID=UPI00114226F3 +--KFKSNINDHVKKCQGRVSIWIEM--DKEII-EINSKQAYPAASLIKVPILIEAFRQKE +EGKLDVEQLVSISKEEKVGGAGVLFSLSSKAFTIHDLMTLMIIVSDNTATNQLIDLI-GW +HEINQCIKALNLTSTRLNRKMMDLD-AIKLGKDNWTSAVNIGTCLKEIYKGSLLSKESKE +EILSMMRKQQF-KEKLPAYMNKGW-IANKTGELE-GIEHDCAIIQYNGI-TVYMAVLIDQ +LSAQ-EDGRETIRQIGKLVNN-- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3D4II70_9BACT +--TLKTDLLQLIAEYSATVGISVIDWTNKQSI-NINGDVRMHAASTMKIPVMIEVFRQTT +VRKLRLKDSLVVKNESIVDGTHFAYRELGKKKSYYDLVFQMITVSSNIATNILIDDL-GA +QNVQQTIERLGTTQMKVRRGVEDTK-AFERGLNNEATANDLALLLTRIAQGKAVGKEEDR +AMIDIMMAQRF-NEMIPKGVPNGVKVAHKTGEIT-AHRHDAAIIYPEKGKPYTLVILIKG +IEDS-EKAYQLGINISQK----- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DDB4EE5 +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DDBB526 +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DD5A68F +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudoxanthomonas wuyuanensis TaxID=1073196 RepID=A0A286CYN6_9GAMM +------------------------------------------------------------ +----------------------------------------------------------GE +PRLQALAQALGVPRSELDATLDALFENYYRRGDNSATLRAFAAVLEQLAAGQLLGPESRQ +RVLGHMRRISTGARRIQAGLPEGADFAQKTGTQI-GRACNLGIIDPDRGDGAVVVVACAE +RFDALAEAEQAFEQLGTALVD-- +>[subseq from] class A beta-lactamase n=1 Tax=Prevotella sp. P6B1 TaxID=1410613 RepID=UPI0009DCDBE5 +-------------------------MRDGSFV-GINENEHFAMHSVMKFPQALCVADYLS +RKGLDLDDTIVVDKADLMQWSPMLKRFECKTFSYAQLLELSLGQSDNNASELLFKFCGKP +KAVEKYMRKLGFHDIHIRMTEEQMHKNPAKAIENSSTPTEMVRLFEWFYHHKD-DNRYLT +FIWKAMADCSTGQKRIPAAIPADARIVHKTGTGFLQDMNDAGIILMPNGSHAIIAIFTTN +SS-----SEAVIANITRQLLD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Pedobacter luteus TaxID=572036 RepID=A0A1T5AAU9_9SPHI +-qKTERQLQDIVSSSPFLTGMMAIDLTTGDSF-SSNQDIVFAQASAIKIPILMEVYKQAK +ENKFALTDTRPLLTTNTVAGSGILNAMVDPVLSIRNYCMLMIGLSDNSATNTLIELV-GL +NNINNTMQSLGLKNTRVQRKMIDQPASIR-NEENISTPAEAAKIMKLLYDGKFVDKATSD +EILLTLQKNPVENSKLVRGIPSGVKIAFKPGGMG-GVSTEWGIIYLAKK-PYAVAVMENY +KA--GPSNQDVFANISKVLYDYy +>[subseq from] Beta-lactamase PSE-4 n=1 Tax=Clostridium roseum TaxID=84029 RepID=A0A1S8KYD7_9CLOT +--ALDNAIKNILALRCEDISLVFLDLNNTSNYiYINENKIFPSASTIKVLILAEALNEVL +NGKLSLDAPIEVKTSDKVPYSILTS-LTNNKYPLIDLLTLMIISSDNTASNILIDLL-TM +ESINNYGQSIGLKNTSLKRKMMDSKA-VQRGMDNLTSAFDMLTLFKKIYNHELLNPKMCD +LILKILGDNTD-KEVLLRYLEADIRCAHKTGDLSN-LNHDIGVFKTKTS-EYILGVFVRN +ADFN-YVAKDLIGKVSKIVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Psychrobacillus sp. OK028 TaxID=1884359 RepID=A0A1H0F2A3_9BACI +-kELVSRVQQLIAASKGTWGIVLEDLNSGERW-EHNEQELFYAASVIKIPIMSSVYSAVD +KGDLTLNDLVVLDKKDYVGGSGVLQHFTPGSLPLQDIIMLMIIQSDNTATNLLIDLV-GV +ENIQNSMKEADMFYSTFYNKLMLSKPN--PEGTNCIAALDIAMLLNKMASGSLVSRTASE +QMIDVMKKQQV-RDCLPEKLPSPWELANKTGWIP-GTRHDVGIFYVGNRK-LMATVLSKD +ED--DLVSKRILSQIGEEIYKY- +>[subseq from] Beta-lactamase n=1 Tax=Chthoniobacter flavus Ellin428 TaxID=497964 RepID=B4CW47_9BACT +-qALHDRIESLRTGSGAAIGVQVFDYETDRTF-SHEGDRWFHAASTMKVAVLLALFHAVD +TGRVRLEDRLHVRNRSIVDRSIFRHRRVGRSMKLIELAEPMITRSSNLATNLLLEFL-TP +DYIQSTLTAAKVDGVRVLRGVEDSV-AFDRGLNNTVTPSGLVALFRLLRENRLLPESARN +RMLAILLAQEF-NSMIPALLPDSAQVAHKTGEIST-CTHDAGLVLLPGRRPYAVAILTEH +PP-GLDDTQKLVAKVSRLVYE-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TTU2014-096BSC TaxID=1729725 RepID=A0A0T6VR87_9PSED +---FLAHIARVDEQTPGRLGVYVKDMETGIST-SYHGEEPWYLASTVKVPVAITVMRRIE +EGALSLDTGVPLLASDYVDGAGATNGFAPNTHSVRFLMEQMLIHSDNTASDMLIRLV-GL +ERVNAVTRELVPEGFGPITTLADVRRRYYATPYNSATLKAYGDLLSALDAGTALNPDSTR +YLLGVMRRAETGARRIKAGLPPTVGFAHKTGTQR-ARICDAGLVDQPTASRRLLIVACVR +EAASTAKAERALRGTGEAVT--- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A354WLY6_9FIRM +-kDLASRLSAVMDAFPAKTALYCVDLTTGTPIaAIRENTRVVSASTIKVPILCCALQDVM +DGKLSLDQHLAIAPADFCSDTEVFEPYRQDGASLWEMLYWMIVSSDNTATNTIISLL-GH +DHVNQYCRTIGLTQTSLQRKMLDFQ-AIAEGRNNYTSPADLYRVFSLLYHGEILNKPLRE +VAFDFLSRCRS-TDALQRYIPDAVTVLHKPGGLDH-LNHDAGIFLTEDR-PYYLGIFTWD +GPDGQPQQNRLIGQLSRMIYDA- +>[subseq from] Serine hydrolase n=3 Tax=Runella sp. TaxID=1960881 RepID=A0A3C1TIM4_9BACT +hpALEQRLADYLAKLSVKVNYRVESLEGKRYA-SLGDDERVPSASIIKIPILVEIMEQVK +AQRFELTDYYTLQNADKVGGAGIFQEREGKAFTYEQLAHQMMVASDNTATNILIRKV-GR +EAVNERMKTLGFPNLQLNRVMMDTAA-VAKGIENYVNADEINRLLSLIYQRKVATPALCD +LMVAFLLDNHD-TSTLPSLIPRQVGIAHKTGTLTY-IRGDAGIIFTQ--KPFVISVFVRG +TD--LNRAETIIAEIGKIAYE-- +>[subseq from] Serine hydrolase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A374NY34_9CLOT +--SLEEEVTEKIRRLPGKTGFYYENLVTGERA-AYHEDERMMAASVIKLFVMTEAFVRFE +EGTLSTDRIIRMKREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTAANVLIDLL-GI +EEINRTIRRMGYRDTVLQRKMYDTEKS-KWGIQNYITAAETGRLLREMYQGRLVSRQASE +KMISILKNQQL-CSKIPQALPEEPEIAHKTGEDC-GITHDVGIVYAKQ--P-FIVCYCGN +DT-DTPAYERVMAETSLWLY--- +>[subseq from] serine hydrolase n=1 Tax=Psychrobacillus sp. OK028 TaxID=1884359 RepID=UPI000B875024 +-kELVSRVQQLIAASKGTWGIVLEDLNSGERW-EHNEQELFYAASVIKIPIMSSVYSAVD +KGDLTLNDLVVLDKKDYVGGSGVLQHFTPGSLPLQDIIMLMIIQSDNTATNLLIDLV-GV +ENIQNSMKEADMFYSTFYNKLMLSKPN--PEGTNCIAALDIAMLLNKMASGSLVSRTASE +QMIDVMKKQQV-RDCLPEKLPSPWELANKTGWIP-GTRHDVGIFYVGNRK-LMATVLSKD +ED--DLVSKRILSQIGEEIYKY- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas sp. PA1(2017) TaxID=1932113 RepID=UPI0009697C3F +---LLERLRATAAKQDGELGVYVKDLHSNLAV-TLQAERLWYMASGIKVPVAIAVLRGVE +RGDWQLDTHLPLAANDFVDGAGSTNQYGPGELSVRFLLEQMIIYSDNTATDRLIRLV-SL +DAVNALVRELAPEGFEPITTLGDVRRAYYRSNLNAATLSAYGELLERLADGQALGQAQTA +YLLEVMGRVKTGSKRIIAGLPKDAHFAHKTGTQR-ARICDSGLIRTPEREPVLIVACV-E +GELSLAKAERTLRQVGEAL---- +>[subseq from] serine hydrolase n=1 Tax=Thermoactinomyces sp. Gus2-1 TaxID=1535750 RepID=UPI000504E565 +-qTLTGSLDAWKKKASGVWGIWMEDLHTGEKW-IWNEKQPFVAASMIKVPVMVAVYRAHA +QGKLCLSDRIRLRREDKVGGSGVLQHLSYGTFSIQDLVTLMIIQSDNTATNLLIDRL-GK +DYVQETILDLEMNDTVFINRLHIVPAG--SNKSNQITAKDMARCFRLLATGQAVSRDASQ +KMIEILKKQQW-RNCLPGWFPPSWEMAHKTGWVNQ-TLHDGGILYIASH-SLILVVLSSG +LDH--HQAQREINHIGKWVYDAy +>[subseq from] ClassA_beta_lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059XDF9_9BACT +-eSLQSRIEKEFSREQGEFALAFEDLATGEQL-LINAGERFHAASTMKTPVMIEVYKQVA +EGRMSLHDSVEVKNTSIVDGSAYSYKQLGHKRTLYSLMYDMIILSSNLATNLVIERV-GA +IHVTATMRGLGAKDIEVLRGVED-NKAYEKGLNNTITAYDQLLIMKKIALGKAVSKEASD +AMMNILFDQRY-RDIVPANLPPEVKVADKRGWLT-GLEHDCAIVVLPNGHRYVLIILSRK +LV-DRDKAVKAMANVSRIIFDH- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas sp. TTU2014-096BSC TaxID=1729725 RepID=UPI000AE48A6D +---FLAHIARVDEQTPGRLGVYVKDMETGIST-SYHGEEPWYLASTVKVPVAITVMRRIE +EGALSLDTGVPLLASDYVDGAGATNGFAPNTHSVRFLMEQMLIHSDNTASDMLIRLV-GL +ERVNAVTRELVPEGFGPITTLADVRRRYYATPYNSATLKAYGDLLSALDAGTALNPDSTR +YLLGVMRRAETGARRIKAGLPPTVGFAHKTGTQR-ARICDAGLVDQPTASRRLLIVACVR +EAASTAKAERALRGTGEAVT--- +>[subseq from] Serine hydrolase n=3 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6B535_9BACT +--TLDEQVERLAAESKARIAIALHDLESGLRF-SLRGDRWFHAASTIKVAVLLSVFRAVD +EGRFRLDDSLHVRNRFISVGSPFYYQAIGQTAKISALAEGMISSSSNLATNLLLDLL-GV +EYARKVLRDAEVEGVELRRGVEDH-AAHEKGMNNEATANGLLTLLSA-VRGDFLSSESKE +QAIRILLEQRF-KSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DP-EREGRRETVAAISEAIYR-- +>[subseq from] Serine hydrolase n=2 Tax=Nonomuraea TaxID=83681 RepID=A0A5C4WYA4_9ACTN +-------FDALFRGAGVTGWLYAADIDSGHEV-GHRPDEPLPTASMFKVPLLVALCRQAD +AGLFDLSERVTVTDADRSPPTGIAAMLDDVTISLRDLAYLMITVSDNTSADVLLGRV-GF +EAVNDMLAAFGLEGTRVTQTCRQLDDVLDPARTNRSTPRELARLFAMIWRDEAASAESCA +WMRGVFNMQVW-PHRLASGFPDDVAVGGKTGTLPT-LRGESGVVEYPDGRRYAVAVITRS +FSLNQPRADAAIGTAARMAVDH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Mycolicibacterium canariasense TaxID=228230 RepID=A0A100WDY1_9MYCO +---------EAELRHQARIGLYALDLKTQNTI-THRNHDRFAMCSSVKTYVAARVLQKAE +RGELALTDSVTVHGADIVPNSPVTETWVGRSIPVAELCAAALQKSDNAATNYLLKTVGGP +SAITEFARSIGDNETRLDRWETELNSATPGDARDT------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2D5QJZ8_9BACT +-nNLENKITNLLKSHKGSFAVALKNLDNGNTI-LINENEIFHAASTMKTPVMIELFKKKH +NGEISFDDSLQIKNESIVDGSKFEYKNLGEYISIRELIFDMITKSSNFGTNLLIDYI-DV +KNVNNTMRDIGAENINVLRGVGDLKA-FDKGLNNTTSAKDLLVIYEKLAMGSLINPSTSN +EMVEILKNQVY-KDIIPKYLPDNVKVAHKTGWIS-GVRHDSGIVFLENGKKYVLILLSKN +LDD-DIEGAEFLAKISLEIFN-- +>[subseq from] Serine hydrolase n=3 Tax=root TaxID=1 RepID=A0A512TPN4_CLOBU +--ELNEKIKEIINESGTDIGILVKDLTNDKVIvNYNENKSYVSASLIKIPIFIEALRRVD +NMEIPLSKEFEIDKIQKVEYSVITEQDLDI-CTYEELMEWMIISSDNSATNVLIDIL-GL +DNINNTVDKFSMNSTKLQRKMMDFK-AIDEGKNNYTSLNDMLLLMEGLYRGNIEEKEICR +RALETLKNQRD-NSMLKRYIKDNVVLANKTGELDN-LNNDVGIFYTKNID-YFIGVFAQN +VNN-NLEGCKIIGSISKVIYEYf +>[subseq from] serine hydrolase n=1 Tax=Micromonospora ureilytica TaxID=709868 RepID=UPI000F5EF0B4 +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVALDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Beta-lactamase PSE-4 n=1 Tax=bacterium HR16 TaxID=2035411 RepID=A0A2H5X0C0_9BACT +--ELFQALFEKIRSVPAEVGLAVRGVDIDLRI-DINSIEPFRSASVIKVPLLAALFWLSE +QGKLDWQERLALRDADRTPGSGILREHTGLNLTLHDLAVLMIVLSDNTATNMLIDRV-GV +ERVQEFLRLVGFHHTTLQRKMYDFAAA-EQGRENLCCAAEIADLLKWMAQGELVSGAGCE +QMLHIMRGQFY-RDQIPALLPDEAKVANKTGEIR-GHHHDSAVVWTPAG-CYTLVVLTRG +FE-HRRVAASFIAELSLMIYR-- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella bivia TaxID=28125 RepID=Q8KT60_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTKEEMSADHNKAYSNYTSPLGAAMLMNRWFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] serine hydrolase n=1 Tax=Muricauda olearia TaxID=552546 RepID=UPI001261F2CD +---LEDKVHAQIDSIEGNVAVAFLNLSDPSDTlYFNENEEFHAASTMKVPVMIELFKQKE +EGKINLNDSILLINESIVDGSSYSYNKINTQVALKDLMYNMITVSSNLATNVLIELV-DA +KKVTATMRDLGAENIEVLRGVEDQK-AYDLGLSNSTTAKDLLIIMEAIATNKAGTKEDCN +DMIAILKDQRF-NDLIPRDLPKNVEVAHKTGWIT-GVHHDAGIVYLPDGQSYVLVLLSKN +IQ-DSDKGTQQLADISKAFYDY- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A4S2BCQ0_PSEST +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLKLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax konjaci TaxID=32040 RepID=A0A1I1UN64_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +QRVQAVARALEVKKADLKGTMDEAYTRYYTRGLNSATLAGYGGMLEQLVRGRLLTPENTQ +MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQWH-RACHMGVIDPQDGARAIVVATCAE +GLDEMRQAGRLFEQLGRTIT--- +>[subseq from] Beta-lactamase n=2 Tax=Francisella hispaniensis TaxID=622488 RepID=F4BKG5_9GAMM +------------------------------------------------------------ +--QGFLDKKIPITQDDIGTYAPITAKNIDKSLTISQLNYAAI-LSDNPAANILVREIGGL +QNLNKFIKKLGDKDTIIIADEPKVNHTKPDSNINKTTPKAITKDIYKLAFGNVLDKKHKD +IFIKYLQDNNTGANRIAFSMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIGLGILYTN +PNKNAPSNEEIIQQAAKLIAN-- +>[subseq from] Serine hydrolase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A3E3DPI8_9CLOT +--SLEEEVTEKIRRLPGKTGFYYENLVTGERA-AYHEDERMMAASVIKLFVMTEAFVRFE +EGTLSPDRIIRMKREDCVPCGALTYLHDGIQVTVLDLVTLMIIFSDNTATNVLIDLL-GI +EEINRTIRRMGYRDTVLQRKMYDTEKS-KRGIQNYITAAETGRLLREMYQGRLVSRQASE +KMISILKNQQL-CSKIPQALPEEPEIAHKTGEDCE-ITHDVGIVYAKQ--P-FIVCYCGN +DT-DTPAYERVMAETSLWLY--- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7959A8 +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI0002E8BD82 +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] Serine hydrolase n=2 Tax=Pseudomonas sp. TaxID=306 RepID=A0A352HXI2_PSESP +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A6A9R0X7_PSEST +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] serine hydrolase n=1 Tax=Salinicola peritrichatus TaxID=1267424 RepID=UPI000DA215A0 +--RLEARLTEIDRQYAGEIGVHVRRPATDERL-GHRDAERWYWASLVKIPVAVELLDRVS +RGDIDLQERMTLAQSDYVDGAGATNWEPGSEIRLRTLLERMLIQSDNTATDMLIRRV-GL +DAVNHRARRLMSDGIGPITTLVDVRRRYYATGLNSGRLDRYADMLARINAGKALDGEATQ +VLLEIMRRATTGHARLAAGFQREWPFAQKTGTQH-ARFCDAGIVNPRTSRAVIIVSCLKG +DP-SRQNANRTFQAIGEAI---- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7AEBAD +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI00030A0F2B +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax valerianellae TaxID=187868 RepID=A0A1G6XR34_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +KRLQALARSLDVAAGALNKTLDEAYDRYYRHQANTATLEGYGAMLEKLVRGQLVSPAHQQ +LLYKDLKFDTYDAYRLEAGLPRSVRFIHKTGTQFH-RACHMGVIDPQNGRRAIVVAACAE +GLDEMKEAGKAFEQIGRAITQ-- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI000E5C837E +--TVEGTIKDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAETTVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] Uncharacterized protein n=1 Tax=Pseudomonas stutzeri (strain A1501) TaxID=379731 RepID=A4VI25_PSEU5 +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora parva TaxID=1464048 RepID=UPI0004C166EE +-------------------GATVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQIFLDDGVLVTPEDVVGGSGQLQFETFPQVTVHRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. AMSO31t TaxID=2650566 RepID=UPI00124B0BB4 +------RIVAAAGTTGNLAGVTVRDLSGGQQV-SVDGRFRPRAASVIKLWIVTELLRRVG +CGQVSLDQRVLVTRADVVGGTGQLQEEIPQLASLYKLAQYTIKYSDNTAANVLINYLGGF +APVNALIDSMNQRETVLARKFLDAEA-VARGEENYTSPDDVISLLGAVWDAQILDPASRD +LLIGFMREQTL-NTKIPAALPPGTPVAHKTGDLPD-VSHDVGYYLIPGEE-TAVAFLTSG +PQ---ATGDQVVRCLARAVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7X8D7_9BACT +------------ERHGERLGIAFWDSETTLQW-AYNADEYFHAASTMKLAVLLGVYRQVG +RGELTLDAPVHVRNKSVVNDQLYMYRNLGRTMTVQQLAYAMITTSSNFATNLLVDVL-GV +STIQTALAELGIDGMKVVRGVEDQ-AAFEAGINNEVTAAGLLKLLRALAEGKAYGAEASA +EMLKILHDQRF-KGGIPAGLPQAARVAHKTGNIAT-VHHDAGIVYLEHRKPYALVILTQF +HSE--TPRSTAVADVSRDIYE-- +>[subseq from] Beta-lactamase class A n=2 Tax=Muricauda sp. ARW7G5W TaxID=2135618 RepID=A0A3D9EQA8_9FLAO +---LEDKVHAQIDFIDGNVAVAFLNLSDPSDTlYINKDEEFHAASTMKVPVMIELFKQKE +EGKINLNDSILLINESIVDGSPYSYNKINTQVALKDLMYSMITVSSNLATNVLIELV-DA +KKVTASMRDLGADNIEVLRGVEDQK-AYDLGLSNSTTAKDLLIIMEAIATNKAGTKEDCD +NMVDILKDQRF-NDIIPHNLPKDVEVAHKTGWIT-GVHHDAGIVYLPNGRSYVLVLLSKN +IQ-DSDKGPQQLADISKTFYDY- +>[subseq from] serine hydrolase n=1 Tax=Prevotella sp. P6B4 TaxID=1410614 RepID=UPI0009DDDB79 +-------------------------MRDGSFV-GINENEHFAMHSVMKFPQALCVADYLS +RKGLDLDDTIVVDKADLMQWSPMLKRFECKTFSYAQLLELSLGQSDNNASELLFKFCGKP +KAVEKYMRKLGFHDIHIRMTEEQMHKNPAKAIENSSTPTEMVRLFEWFYHHKD-DNRYLT +FIWKAMADCSTGQKRIPAAIPADARIVHKTGTGFLQDMNDAGIILMPNGSHAIIAIFTTN +SS-----SEAVIANITRQLL--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Bradyrhizobiaceae bacterium TaxID=2072420 RepID=A0A431RKQ6_9BRAD +------ELESYERESGGRIGVYAENSATGKKL-SWRADERFVMCSTFKASLAACVLARVD +RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVTDMCKAVVELSDNTCANLLLARIGGP +ATLTAFWRSLGDSTSRLDHNEPELNRSPPGNPQD-------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=2 Tax=Bacillus fortis TaxID=254758 RepID=A0A443J0I9_9BACI +------EMKQLLGDLKGKAGAAIEI--DNDCF-YFNHEEVFPSASVIKVPILIEALRQAE +SANIDVNESIQIRH--RVGGSGVLQVLSDQVVTVKDLMTLMITVSDNTATNMMIDLL-GM +DAINTTIKNMGMQKTVLQRKMMDFS-AIERGLNNLTSPADIVTCLKVINQGDFLTEKSRK +LALEIMHAQQFHD-KLSAMIPEAIFVAGKTGSLPQ-VENDCAIFKWGNKT-AYVAVLMDQ +LE-DSYSGRRVISKIGKYLYD-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DDAF706 +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPSGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] serine hydrolase n=1 Tax=Lentibacillus jeotgali TaxID=558169 RepID=UPI0002627C2B +-kQLESEIFSIISDINSPIGLVIKE--GHHSI-AINESMPMPAASVIKIPIIMEAFRQAE +NSGLNLSETLRVPTDAKVGGSGVLQSLSEDAMTLLDVLTLMIIVSDNTASNLALKRV-GI +DNVNRLCHELQCHNTEIQRCFMDMEAA-EKGLENTTTAGDMVKLLAEIAAPNLLRKESAN +SILHIMTQQQLASKLPAYHVNDDVIIANKTGELAH-AEHDVGIFQYQDRT-VTAAVLMVG +NS-DHVAAQHAIARIGKVIMAY- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000651B294 +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7A74C4 +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] Uncharacterized protein n=1 Tax=Ignavibacteria bacterium RIFCSPLOWO2_12_FULL_56_21 TaxID=1798438 RepID=A0A1G0SJH1_9BACT +--KTEVGIREAVNGVKGAAGLIAIDLTNDDTF-AVNENMVFPQGSAIKITVLMEVYRQAA +KGMLTLTDTHPVTAQYQVGGSGVLQTLGDGTLSVRDLCVLMITLSDNTATNMLIDLV-GM +NNINSTLSGLGLKETRVQRRMIDIPAS-KRGEENLSTPAEAARIMTILYKGEFVDRKTSD +AILDILKIPKR--GTINAEVPETIKVAFKPGGIS-GVSTEWAIVYLPQR-PYIVVAMENY +SVGD--EASDMMRKASRLMFDYf +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A3B9TKZ3_PSESP +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] serine hydrolase n=1 Tax=Chitinophaga pinensis TaxID=79329 RepID=UPI00115934EE +-hKLTAKLQALVANFQGEAGIYVEHLKTGRFV-AINADTVFPTASIVKVPLLVGLFDKIE +KGELKYHQPWTYRDSAKYGGSGIMQFFRDSATEVSVLAALMMSYSDNTTSLMIQSMAGGG +ARVNELMEQYGLKDTRVNSRTPGRAEIWKKYGWGQTTPREMARLVTMIRKGEIISPAAGD +RMYRLMCRGYY-DESSLSQLPPNVQAAHKTGSVD-ATRSEVVLVNAPHGD-YVFHIATKN +NKSDDNEAVVLIRNVSATIWNHf +>[subseq from] serine hydrolase n=1 Tax=Acidovorax konjaci TaxID=32040 RepID=UPI000B846025 +------------------------------------------------------------ +----------------------------------------------------------GP +QRVQAVARALEVKKADLKGTMDEAYTRYYTRGLNSATLAGYGGMLEQLVRGRLLTPENTQ +MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQWH-RACHMGVIDPQDGARAIVVATCAE +GLDEMRQAGRLFEQLGRTIT--- +>[subseq from] Uncharacterized protein n=1 Tax=uncultured delta proteobacterium TaxID=34034 RepID=A0A212IYG9_9DELT +---LQKDLETLSKNVHGRVSYIVASADGALDL-RRGEKDRFPSASIIKLPILWSVFSKAA +KGELALTEEMPLRAGDIVDGYGVLKMHVGIGTTIEDLCFLMTVTSDNVATNMLIDKL-GF +AAINADIAACGMPDTVLGRKMLDAEAR-AQGRDNFTTPLDVLTFLKMLRHGGTMPENSRA +RMLAIMHNQCC-NNFIPQYMPEGFRFAHKTGDIQ-GTVHDAGILYGPSGREYYVIVLCSD +LAD-------------------- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000BA94384 +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI00105B26E4 +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] Beta-lactamase family protein n=1 Tax=Micromonospora sp. CNZ322 TaxID=2572904 RepID=A0A560AX33_9ACTN +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILAPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000D229E0D +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] Serine hydrolase n=1 Tax=Microbispora hainanensis TaxID=568844 RepID=A0A544YKS0_9ACTN +--------------AGVMGWLHAVDIDDGREV-GLRADEPVVLASVFKVALLLELHRQAE +RGLLDLTERVRVPAADRTGGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLARV-GR +EAVNALLDGLGLTVTRVTQDCREMLTALDPAVANRSTPREMTRLLAMIWRDEAAGAASCA +AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +YGQNQPRADAAIGTAARMAIDQ- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. CAG:924 TaxID=1262938 RepID=R5FRD0_9BACT +---LTDSISQIVSACPGEIGVAVI-INNTDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRGKLNLWSPMIKDYSEPILTVRDLLRYTLTQSDNNASNFMFKDIVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIGDEKQS +FIKNTLKECKTGVDRIAAPLKKGVTIAHKTGSGYNGAHNDVAFICLPNNTCYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase enzyme family protein n=1 Tax=Micromonospora zamorensis TaxID=709883 RepID=A0A1C5GQC0_9ACTN +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVALDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLARYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A0H3YV17_PSEST +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured Eubacterium sp. TaxID=165185 RepID=A0A1C6L793_9FIRM +---LKEQLIAYLKKENVQGAFLIKDLSDGETL-CHNECLKVPSASLIKMYILVEAFRCIK +IGSLTLDKEIAVKKEDLVDFSVL-QFLRPRLYSLEELLSLMVVYSDNTATNVLVDYF-GM +ASLNELMQQIGCRTSVIQRKMMDFAAA-EEGRQNYTSVMDMTSLLERLYQGSLLGQPFDA +QMLDIMKGQAD-EEAMRRDLPDELVIARKSGELD-ALDHDIAIVYTEKRN-YIYVFFSWE +-TGDNNCGRKVLAETSKLVFDYf +>[subseq from] Serine hydrolase n=1 Tax=Pigmentiphaga aceris TaxID=1940612 RepID=A0A5C0ASD4_9BURK +---LLPALQDIAARANGDLGVSVIDLVGGASC-AVRADDSFPLHSMVKLVVAASVAYRIE +QGAFGLQTLVALSQATRPGGVGPLREQGDQTASVERLLEAILLYSDNAACDGLMALVGGP +SVINADLRRWSVADMRVDRTMRELYAAWLADPRDRTTPTAYADFARRLAGGSLLGAQATS +IVMNGWQRSTLTPNRITAGLGAGWSVASRSGTGPTTSTNHAVLATSPAGRPVLVAAFLRN +AAGADAERAMVLADVGRAVAT-- +>[subseq from] Beta-lactamase n=1 Tax=Akkermansia muciniphila CAG:154 TaxID=1263034 RepID=R6J0V1_9BACT +-------------------------------------------------MLALSVLKRVD +QGAMNLEQIIRIRPEQLVKWSPLRERSPQGGFSLKELLRVTVQESDNNTCDLLFSLIGGP +QAVQKDLTEWGIDGINVRFTEDEIHRNRDLQYANSSRPSAMNSLLRAFDEGKILKKGTQR +FLWDIMAGCSTGHERLKGQLSRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD +SKDSESACDRMIASMARWLCMEw +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A368CSD1_PSESP +------------------------------------------------------------ +------------------------------------------------------------ +-------RVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus panacihumi W25 TaxID=1408254 RepID=V6M611_9BACL +---LKKQLSQIVEDAKGTWGIVVEEIGQGICF-EHLPDQSFIAESVIKVPIMAAVFAAAW +QGEFSLEDRLALRREDMVHGSGMLFALSPGLLSIRELATLMIIQSDNTATNILIDLV-GK +ERIEQTMRELGMKESRYVRKLMIYPADNPG--NNTITARDVTTMLSRLGAGRFLSAKACE +EMVDIMKKQQF-RNGLPSLLPTDWEIACKSGWDT-GRQHDAGLLYVQGR-CFAITALSQD +VE--AEEALHTLGSIGKAVYEY- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium butyricum TaxID=1492 RepID=A0A427SHQ9_CLOBU +--ELNEKIKEIINESGTDIGILVKDLTNDKVIvNYNENKSYVSASLIKIPIFIEALRRVD +NMEIPLSKEFEIDKIQKVEYSVITEQDLDI-CTYEELMEWMIISSDNSATNVLIDIL-GL +DNINNIVDKFSMNSTKLQRKMMDFK-AIDEGKNNYTSLNDMLLLMEGLYRGNIEEKEICR +RALETLKNQRD-NSMLKRYIKDNVVLANKTGELDN-LNNDVGIFYTKNID-YFIGVFAQN +VNN-NLEGCKIIGSISKVIYEYf +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus saniviri TaxID=931533 RepID=UPI0006CFC593 +-------------------------------------NRPQRAASTIKLFILATAYAKVS +RGQFNLDQHYTLQETDKVGGTGVLGGQAAGTLSYRDLLNDMITQSDNTATNIIINLVGGM +PAVNAEIRQLGARDSQLNRKMMDTAK-LTAGVDNVTSVQDVGHLLQRLYRHQLLSADADT +QMLNILQRTQN-HSKLPASLPATATVYNKTGEFDYGVQNDAAIIADKKGA-FVAVVMCQN +GNE--AAQISAMRQLGSALY--- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Marinimicrobia bacterium MT.SAG.3 TaxID=2552982 RepID=A0A4Y8I409_9BACT +-------------PAGSEVSVAYENLQTGSKM-FVNAKEQMHAASTYKTALMIEVYKQTA +EGKISLTDSIDVVNSSIVDDSEYAYELIGKKASYFDLTYQMITVSSNLATNLLMNEV-GA +KNIMKTLESIGVKEMQVLRGVDDLK-AYELGLNNTTNAEDMLRLMIAIAKDEVVSPSACA +EMRKMLLAQVD-NSKIPAKLPKEVKVAHKTGSITK-IDHDVAIIYPPKGPVYSLVVLTRG +IK-EHKDAEELIADISKIVYD-- +>[subseq from] Serine hydrolase n=2 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A210Y0F6_PSEST +------------------------------------------------------------ +------------------------------------------------------------ +-------RVLNLRQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] Beta-lactamase class A n=1 Tax=Singulisphaera sp. GP187 TaxID=1882752 RepID=A0A1N6I0A8_9BACT +--TLESRLMPLIQAHKGKVSVAIKNLKTGETF-LYHEDVPMPTASLIKLPIMVETYRQAE +EKKVDLGEMITLKQSDKVPGSGILTDHFSAGFPLLDAIHLMIVYSDNTATNLVLDKI-GI +GSTAETMEKLGYPHTKAHSKVFRRDTRSKQFGLGSTTASEMIRLCESLQKGELISKEASE +AMLKHLRACDD-KDKFPRFLPPGTKVAFKTGSVD-ASKTAAGLIECGQG-PVAVCVMTDE +NEVTDNAGNRLCAEVARVVFEHf +>[subseq from] serine hydrolase n=1 Tax=Xanthomonas sp. Mitacek01 TaxID=1732019 RepID=UPI0006DBA61E +--ALDRRVRAIDARLTGEIGVHVQRLDGGTQY-GFRASEVWYLASGVKVPIAIAVLREIE +QGWLTLDTQVTLRADDFVDGAGGTNAHRAGDLTIAWLLEQMIVHSDNTASDVLIRTV-GL +GQVNAVASELIARDVRITT-LADVRRSYYATHANSATLRDYGHMLAALQAGDALGPDGTR +YLLDVMARVQTGKQRIRAGLPAGARFAHKTGTQYR-RICDSGIVTMPARAPVQVVVTACV +RGAGTAASERALRELGAALT--- +>[subseq from] Uncharacterized protein n=1 Tax=Micromonospora sp. 5R2A7 TaxID=2202421 RepID=A0A317CV13_9ACTN +------------------AGVTVRDLSGDQQV-AVNGALRPKAASVIKLWILVELLRRVD +CGQVSLDDGVLVTPADVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNIAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSE-TAVAFLTAG +PM---DTGDETVRRMARTVYD-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DDA4A8A +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPQDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=marine metagenome TaxID=408172 RepID=A0A381P820_9ZZZZ +----EKKIISKFNDETGNFALAFKNLDDGKEI-LINENEIFHAASTMKTPVMIEFYKQLH +QGKLSLEDTLQIKNESIVDGTMYKYNKLGQYYSINNLIYEMITISSNFATNILIDYI-GA +NNVTKSMKEIGALNIDILRGVEDIKA-FELGLNNTTSAKDLLIIYEKLAKGKIINNESSA +IMIDILKDQKY-DDIIPKYLPKDIEIANKTGMIT-GVHHDSGIVFLKDGKKYVIIILSKN +MS-DMESGTEMMAKISELIYK-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodothermaeota bacterium MED-G18 TaxID=1986239 RepID=A0A2A5X8V1_9BACT +---LENKISNLIKSHKGTFAVALKSLDDGNTI-LINENEIFHAASTMKTPVMIELFKKKH +NGEISFEDSLQIKNESIVDGSKFVYKKLGKYISIRELVSAMITKSSNFSTNLLIDYI-NV +KNVNKTMRDMGAENINVLRGVGDLKA-FDKGLNNTTSAKDLLVIYEKLAMGSFINPSISN +EMVEILKNQVY-NDIIPKYLPDNVEVAHKTGWIS-GVRHDSGIVFLENGKKYILILLSKN +LDD-DIEGAEFLAKISLEIFN-- +>[subseq from] Serine hydrolase n=1 Tax=Flavobacteriaceae bacterium 10Alg115 TaxID=2584122 RepID=A0A5B7U0I7_9FLAO +-eNLESTILSQIDSIDGTVAVAFFNLSAPEDSlFINIDEKFHAASTMKVPVMIELFKQAA +QGKFNLNDSVFLKNESIVDSSLYSYNKINKKVAIKDLMYSMITASSNLATNVLIELV-DA +KKVTATMRDLGAKDIEVLRGVEDLKA-FEKGLSNSTTARDLMIIMKAIAQHKAGSEADSK +AMIAVLEDQLF-KSIIPKYLPKTLKVAHKTGSIT-GVHHDAGIVYLPDGKSYVLVILSKN +IKNS-DTATQQLARISKTIYDY- +>[subseq from] NLP/P60 protein n=1 Tax=Alkaliphilus metalliredigens (strain QYMF) TaxID=293826 RepID=A6TPV9_ALKMQ +---LKEQILEVLMETEAQVSVSIKDMSRNQWViRLNDTHKMPSASIIKLLIMIEAFCQVE +EKKFQLNQSLTIPKQDQIPHSMTTDL-EENTFQFVDLVQLMITVSDNTATNVLIDLL-GF +ENINQRAEKLGLKETVLSRKMLDFKAA-KEGRQNLTHGEDAIRMMELIVTEQAASPPMCR +RMMDILFNQQD-REMLRRFIPKKVKVAHKTGDLPN-LNHDVGWVLLSDM-SYLIGVFVNG +AA-DNLEAKTIIGKISKLAYDYf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7YXG8_9BACT +----------------ENLGIAFYDAQTTIQW-AYNGDQYFHAASTMKLAVLLGVFRQVE +RGELSLEAAVHIRNRSIVNQQPFMYGHLGRTLTIRELAYWMITKSSNLATNLLVEVV-GV +PTIQHALDELEIDGVRILRGVEDQ-AAFEAGLNNEVTANGLLKMLRLIADGRAYSKVASD +EMLNIMLEQQY-RSGIPAGLPKAARVAHKTGNIST-VHHDAGIVFVEDRKPYVLVILTQF +PAES--ARGTAVADVSRDIYN-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium butyricum TaxID=1492 RepID=UPI0002D1BCFE +--ELNEKIKEIINESGTDIGILVKDLTNDKVIiNYNENKSYVSASLIKIPIFIEALRRVD +NMEIPLSKEFEIDKIQKVEYSVITEQDLDI-CTYEELMEWMIISSDNSATNVLIDIL-GL +DNINNIVDKFSMNSTKLQRKMMDFK-AIDEGKNNYTSLNDMLLLMEGLYRGNIEEKEICR +RALETLKNQRD-NSMLKRYIKDNVVLANKTGELDN-LNNDVGIFYTKNID-YFIGVFAQN +VNN-NLEGCKIIGSISKVIYEYf +>[subseq from] serine hydrolase n=1 Tax=Millionella massiliensis TaxID=1871023 RepID=UPI0009F37F9E +---LRKKLETAISDVPGRVGIAVIS-PEGDTL-TVNNGGDYQLMSVFKLHQALAVAHALD +LQGVSLDTVIRVRRTEFDPWSPVLTEKSDSLLTVTEWLSYLLQQSDNNVSNMLFQRIASV +AATDSFIRATGITDFRLTVMEEQMHRDHSLADGNRSTPLACASLIRKVFNDSLVSPAKQE +AIRRILSECRTGLDRIHVPLAPSVTLAHKTGSGFRTAHNDVGYVTLPDGRAYALAVLVKD +FDGSEAEASAVIAKVSEIVYEAy +>[subseq from] Beta-lactamase n=2 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A174L833_9CLOT +--SLEEEVTEKIRRLPGKTGFYYENLVTGERA-AYHEDERMMAASVIKLFVMTEAFVRFE +EGTLNPDRIIRMKREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTATNVLIDLL-GI +EEINRTIRRMGYRDTVLQRKMYDTEKS-KRGIQNYITAAETGRLLREMYQGRLVSRQASE +KMISILKNQQL-CSKIPQALPEEPEIAHKTGEDC-GITHDVGIVYAKQ--P-FIVCYCGN +DT-DTPAYERVMAETSLWLY--- +>[subseq from] Serine hydrolase n=1 Tax=Oceanobacillus chungangensis TaxID=1229152 RepID=A0A3D8PWP7_9BACI +-eQLSQSIERIIEQAGGKWGISIEELDTNNSW-SLNEEELFYAVSIIKIPIMIAVFTAYE +KEKLYLSDTLELKVEEMVGGSGVLQHLSPGILTINDLITLMIIQSDNTATNMLINLI-EK +KNIQQTMKDIGMQKSKFYNKLMTVPATLQG--YNEITAQEVTMMLKKIATGKIISRHACE +RMLAIMKKQQL-TDCLPAKLRPEWQLANKTGFVS-GMRHDIGIFYVGDR-VMVTTVLSKG +LD--DNHSKDAIAKVGLEIYHY- +>[subseq from] serine hydrolase n=1 Tax=Lentibacillus sediminis TaxID=1940529 RepID=UPI000C1C4E84 +-qKLIEKVQSTIQATGGEWGIVLEDLNTGEKW-EHHADNLFYAASVIKLPIMAAVFAESE +KGNIDIHGTLSLRKEDMVGGSGVLQHMTQNPLAIYDLMMLMIIQSDNTATNVLIDLV-GV +DNIQKTMQEIGMEKSSFYHKMMIGDRK----VKNELTSRDVGVFLKKLHKGGVVSAEASN +QMIDIMKRQQI-RDCLAGDLPARWELANKTGWVP-GVRHDVGIFSVGDE-CIAVSVLSCG +AD--DLESRRGLAEIGESVY--- +>[subseq from] Zinc-ribbon domain-containing protein n=1 Tax=Pediococcus stilesii TaxID=331679 RepID=A0A5R9BVA4_9LACO +--KVEGTIEDAFGDISGTTSVYVSPTDSSEKVvSHNGAQR--AASNIKLFIMVTAYNAIS +EGQLNLDDEYTLKDSDKVDGTGAIRETAGTKLTIQRLIDYMMEDSDNTAANIMIRELGGM +DAVNKQIKKMGATDTKLERMLMDTD-ALKSGKDNYTSVTDLGETLKKIYNHQMISTKYDN +AMLDVLKQNKN-RTKLPHDLPDEATVYNKTGEFDYGVENDAAIFGNTKG-SFVIVVMSED +GQRNEQ----------------- +>[subseq from] Serine hydrolase n=2 Tax=Clostridium TaxID=1485 RepID=A0A3M0SNK3_9CLOT +------KILNAIDLKKLNCAFVIENLKTGEKI-AYNENVVVSSASLIKIPIMMEILNQVK +EGKLSLKQRITVEDDVKVPFSILNLLESGNSYTLKDVITLMIIQSDNTAANILMDLA-GM +DNVNNYIKDLEIKNTVLQRKMLDSKAR-KEGRENKTTAADMAKFFEIIYKGEKAKEFYSV +IMKNILTSQLD-NSVMRLNIPDDIRIAHKTGDLN-GISHDAGIVYLPNVD-YIFCGLTWD +AV-TNNFARETIGKISKIAYDYf +>[subseq from] serine hydrolase n=1 Tax=Bacillus novalis TaxID=220687 RepID=UPI000826BB9B +---LEEKIKGEITCFQGRIGIAVEI--ANKRI-SLNSVEVFPSASVIKVPILIEGLRQAE +TGKINLNELTTIDK--RVGGSGVLQALSAKVMTIKDLMTLMITVSDNTTTNLLIDLL-GM +DSINSTIEKLSMEHTKLSRKMMDFE-AIEQGYNNFTSPSDMIKCLKVINEGDFLSEESRK +LAVEIMHYQQF-HDKLTAMMDDRVFAASKTGGLPN-VEHDCAILKYGGKT--AYAVVLTD +QLDNHFAAKQLISKIGKHLYDH- +>[subseq from] serine hydrolase n=1 Tax=Paludisphaera sp. JC670 TaxID=2712865 RepID=UPI0013EB3C10 +--DLAGRIEALAKAHKGKAAVAFKNLQTGESY-ALDADAPMPTASLVKFPVMIEAYRQAA +EGKVDLDSPVMLTKKDKVPGSGVLTSHFSEGFPLLDAVHLMITYSDNTATNLVLDAI-GI +GSTAATMEALGCPNTKIHSKVYRRDTRSKVYGLGSTTAAEMIRLFEALHARKLVDEKASE +AMWKHLLTCDD-RAKFPRFLPPGTKVAFKTGSVD-ASRTCAGVIETKGG-PVALCVLTDE +NESDDNAGNLLCAKIAREVYDHf +>[subseq from] Serine hydrolase n=1 Tax=Gelidibacter gilvus TaxID=59602 RepID=A0A4Q0XFZ4_9FLAO +-eTLEKTIQAQIDSIDGTVAVAFYSLYQPKDSlLINVDEKFHAASTMKVPVMIELFKQAS +EGKLNLKDSILLKNESIVDGSLYSYSQIGTKVAISDLMHSMITVSSNLATNILIELV-DA +QKVTATMRSLGAKNIDVLRGVEDQK-AYDKGLSNATTAKDLMIIMEAIATHTAGKQQDCD +AMITILKDQQH-KDVIPVYLPKEVEVAHKTGSIT-GVHHDAGIIYLPNGRAYILVLLSKN +LK-DFDKGTDQLAKLSKTVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Rubrivirga marina TaxID=1196024 RepID=A0A271J0B9_9BACT +-----------LARHAATVAVVVRRAAPGDTV-AYNADRPFHAASTMKVPVMIEAFRQVE +TGLRAWDDPVRVENRSIVDGSEFAYSRLGQDVPFRDLVERAITTSSNLATNLLIDRL-TA +DSVQATAVRLGAPGMRVLRGVEDLKA-FEAGLNNRTTAGALATLMEALRDGRAVSPEADA +AMVDVLDDQAF-NEMIPADLPAGVRVAHKTGEITE-IHHDAAIVYPEGAAPYVLVILTEG +LE-DHAESARLGAEVSRAIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A3D2Y6V7_PSESP +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI0005EB135E +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGAMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI000922A6EB +--TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] serine hydrolase n=1 Tax=Emergencia timonensis TaxID=1776384 RepID=UPI00082CAFA9 +--------------EKVQGAFLIKDLSDGETF-CYNEYLKVPSASLIKMYILVEAFRRIK +GGLLTLDEEIAVQKEDLVDFSVL-QFLRPRIYSLEELLRLMVVYSDNTATNVLVDYF-SM +SSLNELMQQIGCKTSVIQRKMMDFAAA-EEGRQNYTSVIDMASLLERLYQGKLLGQPFDA +QMLDIMKGQAD-EEAMRRDLPDELIIARKSGELD-ALDHDIAIVYAEKRN-YIYVFFSWE +-TGDNNRGRKVLAETSRLVFDYf +>[subseq from] serine hydrolase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DD636EF +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---STGDETVRRMARTVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7VA21_9BACT +-dRLRERIEAIDRTLDGVCGVAVRDHRTGATI-ELRADELFPAASTIKLAILYELFRQAE +EGRVDLAE-VTRPPLPRVGGGGILQRLGGRVLTWRDLSVLMIGWSDNEAANLLAGKV-GM +DAVNRRLDTLGLARTRLRRRMMDLAAA-REGRENVSTPAELARLAEAVAYGTGLPAELAR +DLRAVAATPES-HTAFRAALPEPLVAYTKSGELE-AVRCEVGYVDLPGR-PYTAAVMTTY +LRRD-ADGEAAIRDVSAAVYDTf +>[subseq from] Uncharacterized protein n=1 Tax=Fictibacillus arsenicus TaxID=255247 RepID=A0A1V3G5G4_9BACI +-kQIENDLLRLISSGKGTYGISIYYFETEEEF-VYNHDEEFYAASIIKIPIMSAVLAQVS +EGKRSLSDKIRVRSEDMVSGDGILKNLTPGTWTIHDLVVLMIIESDNTATNLLIDIL-GV +ENIQLYMTIWGFKQTQFRHKLQ-IKPSRKHNESNLITAKEMNHFLRDIAMGNIVSMSVCR +KMIEIMKQQKM-NDLLPSLLPENWEMAHKTGYVP-GVEHNVGLFYLPGHT-FAISALSKN +VP-NRDEPKRIMSELGSLLF--- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. M05W1-28 TaxID=2420510 RepID=A0A420VUR6_9SPHI +-rKLEQQIKQLIHGFQGEVGVYVHDLKKHKEV-NIGADSIFPTASVVKIPILVGVFDKIE +KGQLQLDQELVYRESQKYGGSGLMQFFKDSSVDLKTLIALMLSYSDNVTSIWNQKLAGGG +IAINTLMADLQLRHTRVNSQTEGRKTDWEKYGWGQTTPKEMADLLTLIRQGKVISEKSSD +RMYRFLGNMFY-DERGLSQIPSTVKAASKTGSLDD-VRNEVMLVNAPKGD-YVFSIFTKN +NQGKTNAAEVLTRKLSKLLWDYy +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI0013302D75 +--TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] Zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=A0A6A4XJB7_PEDAC +--TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] Uncharacterized protein n=2 Tax=Halomonas sp. KO116 TaxID=1504981 RepID=A0A0D5LZM1_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +-RAQALARALGVSTFFTQPDYDHAFDAYEATGENVGTLRAFGDLLASLHGGMDLSAEQRQ +TLLAVMQRTSSGKRRLKAGLGSGVSFAHKTGTQQR-RSCDAGIAKRDTEGPWVIVSCARG +PV-AVSAHERALASVGEA----- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI000BEF0549 +--TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] serine hydrolase n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI000466DCE7 +--TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] Beta-lactamase domain-containing protein (Fragment) n=2 Tax=marine sediment metagenome TaxID=412755 RepID=X1IKI5_9ZZZZ +------------------------------------------------------------ +---------------------------------------------------------GGP +KELTAFLHNMGDHVTRLDRWEPELNEVIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] hypothetical protein n=1 Tax=Micromonospora chokoriensis TaxID=356851 RepID=UPI0012F7BD4E +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVALDDGVLVTPQDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. 5R2A7 TaxID=2202421 RepID=UPI0011B436B0 +------------------AGVTVRDLSGDQQV-AVNGALRPKAASVIKLWILVELLRRVD +CGQVSLDDGVLVTPADVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNIAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSE-TAVAFLTAG +PM---DTGDETVRRMARTVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E7U145_9BACT +--DLASRIEANLDALNAKTSFYAKHLPSGREI-AIRADEPMNALSVIKIPIMVLAYRDAD +AGALDLDERYQVQPEDMRRGSGLLQSFTPGIPTYRDIITQMIITSDNTATDVMINRL-GL +ERVNTMLTELGFEQTRLRATTGELFKGDSTQWLGRITAREISQMLEAIEEGEFASPESSD +EMIGILRRQFY-RSMLPQRLRDRASIAHKTGGWPPDAANDVGILYYEGG-PIVVAVFTNQ +NKGNFFELEATVGRIAADLVDHw +>[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus thermotolerans TaxID=338644 RepID=A0A3S6Z786_9FIRM +-------LREWIGTLPGIYGVFAKNLDTGKVF-TFNDTKVFPSASTIKVPILIELYRRVE +EEHLSLDHLLVMRREDQVGGSGVLKDLSPNTYSLRDLATLMITVSDNTATNLLIDFL-TI +EAVNITLRRLGVTHTELVRRLQRVPA-EPLDTVNHTTAQNMGLLMEKLARGTAISLAASE +QMVSLLKRCQG-PISITKLTAESIVIAHKTGSLAQ-ASHDVGIVYSPHLR-YVAALLSQG +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Laceyella sacchari TaxID=37482 RepID=A0A2I7SSU4_LACSH +--RLIQNLEHWKSRAVGNWGVWIEDLTSATTW-AWNETKSFYAASIIKVPIMVAVYKQAF +LGRLALADEIILTAEDQVGGTGVLQHLSPGLFSVQDLTTLMIIQSDNTATNILIDLL-GT +ETIRETMDELGMRQSTFHNKLMIVPAAPAG--LNMITAADVARCFRHIAQGKVVSQHASR +QMVEILKKQQL-RDCLPTGLPSQWELAHKTGMVTR-TLHDAGILFTKSRA-VVMVALSEE +CE--YEQAQQQMKQLARLVYE-- +>[subseq from] serine hydrolase n=1 Tax=Roseimicrobium sp. ORNL1 TaxID=2711231 RepID=UPI0013E14269 +----------------VRASVAAYDHETGRTF-GWHEQEWFHAASTMKVAVLLAVFRAVD +EKRLRLDDPLHVRNRFISAGEPFRHQRIGRTMRIRELAHRMITVSSNLATNLLLDLI-GL +EYAQRVLHDAGVTGIHLKRGVEDAA-AHEMGINNEVTSAGLVSLFRVIQEGQFTTAKSRE +AMLQILFDQKY-NAVLPKKLPPGTRVAHKTGEIST-VSHDAGLFFVKERPPYAFAILTEV +LPES-NGRTATVAAMSEAVCDYf +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. CNZ322 TaxID=2572904 RepID=UPI0011A2DA93 +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILAPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. 3-3 TaxID=2070757 RepID=UPI000CDA4F52 +--ELNEKIKEIINESGTDIGILVKDLTNDKVIvNYNENKSYISASLIKIPIFIEALRRVD +NMEIPLSKEFEIDKIQKVEYSVITEQDLDI-CTYEELMEWMIISSDNSATNVLIDIL-GL +DNINNTVDKFSMNSTKLQRKMMDFK-AIDEGKNNYTSLNDMLLLMEGLYRGNIEEKEICR +RALETLKNQRD-NSMLKRYIKDNVVLANKTGELDN-LNNDVGIFYTKNID-YFIGVFAQN +VNN-NLEGCKIIGSISKVIYEYf +>[subseq from] Beta-lactamase class A n=1 Tax=Pediococcus stilesii TaxID=331679 RepID=A0A0R2KXT6_9LACO +--KVEGTIEDAFGDISGTTSVYVSPTDSSEKVvSHNGAQR--AASNIKLFIMITAYNAIS +EGQLNLDDEYTLKDSDKVDGTGAIRETAGTKLTIQRLIDYMMEDSDNTAANIMIRELGGM +DAVNKQIKKMGATDTKLERMLMDTD-ALKSGKDNYTSVTDLGETLKKIYNHQMISTKYDN +AMLDVLKQNKN-RTKLPHDLPNEATVYNKTGEFDYGVENDAAIFGNTKG-SFVIVVMSED +GQRNEQ----------------- +>[subseq from] Serine hydrolase n=1 Tax=Blastopirellula marina TaxID=124 RepID=A0A2S8FR35_9BACT +--ELRNLLMPLIEKHRGDVGVVIKHVPSGEMF-SYQADQPMSTASLIKLPLLMATYEKVH +AGDTSLDSMITLEESDKVPGSGILTKHFSPGLSLRDAIQLMVAYSDNTATNLVIDEV-GL +DTTNALMKKLECGETRLNSKVFRRDTRSKAFGLGSTSANDMLVMLTALHDRSFVDKATSD +QIMKHLYDCED-RMKAARYLPASVKVAHKGGSVN-AARTDAGIIDLPEGGSILFCILTMN +NKTDENEGDVLSADIGKSVYDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium siyangense TaxID=459529 RepID=A0A562MGU0_9SPHI +-kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE +KGELQLDQQLLYRASQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQNLAGGG +VAINKLMSELQLTQTRVNSQTEGRKSDWERYGWGQTTPKEMADLVTLIRQGKVVSPKSSD +QMYRFMGNMFY-DERGLSQIPSTVKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN +NTGKTNEAEVLTRKLSKLLWDYy +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudobacter ginsenosidimutans TaxID=661488 RepID=A0A4Q7N6A6_9BACT +----------FASHPEGYFAIAFKDLSSGKTF-FMNEHASFHAASTMKTPVLIETFRQAS +KKRFKIEDPIEIKNSSIVDGSPYSYTHIGQKLPISDVLHRMITKSSNLATNIMIDLV-DA +KKVMATMRSLGAKDIQVLRGVEDDK-AFEKGLNNTTTAFDLMLIMEHLANGTAVNKKASE +AMIKILMDQYF-RDVIPAKLPADVKVASKSGSIT-GICHDSGIVFLPDGRKYIIVLLSKG +IK-DHKEATNTLANASRIIYDHy +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus sp. WF146 TaxID=319501 RepID=A0A1A5WUU4_9BACL +------SIGKLMEETGGQWGIYLEDVRTGERL-GFAEHQRFYAASLIKVPIMTAVFAEAY +AGRLALSDKLRLRREDQVGGDGVLQHLTPGTLTVYDAVTLMIIQSDNTATNMLIDLV-GT +DAIRAAMSRTEMVNSSFYNKLMIVPAEPEG--YNEVTAADMGSHFRCLATGKAISYNSCL +HMINILKRQQH-RDRIPCRLPPKWELANKTGTVTN-ITHDAGILYVGGHA-VIICALSKN +VD--AKAAGEMMGQIGRMVYDLy +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI00132F8381 +--TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN +EGKLNLNDKYTLKDSDKVNGTGIRNMSSGTEISIQDLLEDMMEDSDNTAANIVIRQLGGM +NKVNAQIKKIGAKDTKLERMLMDMD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN +AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD +GSRDE-QIK-------------- +>[subseq from] Serine hydrolase n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=A0A1L6H7Z3_PEDAC +--TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FIIVVMSQD +GQRDE--QINAM----------- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroidetes bacterium OLB12 TaxID=1619897 RepID=A0A136LLA7_9BACT +--ETIQQIQEILSKPTGTFALAYKDLITGDEI-LINEHELFHAASTMKTPVMVEVYRQAA +AGKFSLKDSILIKNESILDGSPYSYDHIGEKRTVYSLMHDMIIISSNLATNLIVELV-DA +KNVNQTMRAMGANDIQILRGVEDTK-AYEAGMNNQVTAYDLMLLFEKIDKEEIVNEEASM +AMMDILLDQKF-NDIIPAKLPANVKVAHKTGFIT-GVHHDSGIVFLPDGKKYVLVLLSKG +LK-DETAGIEAMANVSELLYHY- +>[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SD09_9BACT +------------------------------------------------------------ +-------------------------------LSFSEIIKSTVSHSDNNGCDILFRFVGGT +NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTDWTTPDATVQLLKKFYKNEILSKNSYD +FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD +SSEKSDVNEKIIAEICKSVWDY- +>[subseq from] Uncharacterized protein n=1 Tax=Halotalea alkalilenta TaxID=376489 RepID=A0A172YJ61_9GAMM +------------------------------------------------------------ +------------------------------------------------------AAI-GP +RRVDAVARALGVERAELEDDIDAAYADYYAQGDNSAALADVARLFEGLVEGELLNSEHRA +LLYRLMKIDRYEAYRLEGGLDETTEFIHKTGTQRE-RACHAGVIDPSDPERAIVVIACTQ +DMDEASPSETLLEQVGASI---- +>[subseq from] serine hydrolase n=1 Tax=Saccharospirillum mangrovi TaxID=2161747 RepID=UPI000D39A9B3 +--SLNARLLQIDADFPGELGVYVKDLRTGESV-GLREMEPWYLASTVKIAVAITLLEAVD +AGQLTLDQRVELQPLDYVDGAGDTNRLTPGTVSVRYLFEQMLIHSDNTATDVLLRLL-GT +DAVNQVARSVGFGVGRI------------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Muricauda olearia TaxID=552546 RepID=A0A444VPM2_9FLAO +---LEDKVHAQIDSIEGNVAVAFLNLSDPSDTlYINENEEFHAASTMKVPVMIELFKQKE +EGKINLNDSILLINESIVDGSSYSYNKINTQVALKDLMYNMITVSGNLATNVLIELV-DA +KKVTATMRDLGAENIEVLRGVEDQK-AYDLGLSNSTTAKDLLIIMEAIATNKAGTKEDCN +DMIAILKDQRF-NDLIPRDLPKNVEVAHKTGWIT-GVHHDAGIVYLPDGQSYVLVLLSKN +IQ-DSDKGTQQLADISKAFYDY- +>[subseq from] serine hydrolase n=1 Tax=Caulobacter sp. URHA0033 TaxID=1298862 RepID=UPI0004837947 +-qKMTADFQPIADRVPGQLGVAVEDLGTGQII-SFNGERRFPLQGAALIPLGAAVMAEVE +AGRLRLDDVVLIEDVDLSPPSAIADAWPGRNYTVEELLERAVGQGDATAADVLLKRVGGP +GAVTAWLQGRRVNNLDLDRYQRQLLPAALADPRDTATPLGVVRLLEALNQAELLGPESRR +RLGRIIGQTREGPGRLRAALPDGAHLVHLPATARTDMVGDVGVYTLKDGRKFAVIAFVSG +SPLPVAAQEQAIADVGRVVIK-- +>[subseq from] Beta-lactamase PSE-4 n=1 Tax=Clostridium felsineum DSM 794 TaxID=1121310 RepID=A0A1S8LAV5_9CLOT +--ALDNAIKNILALRCEDISLVFLDLNNTSNYiYINENKIFPSASTIKVLILAEALNEVL +NGKLSLDAPIEVKTSDKVPYSILTS-LTNNKYPLIDLLTLMIISSDNTASNILIDLL-TM +DSINNYGQSIGLKNTSLKRKMMDSKA-VQRGMDNLTSAFDMLTLFKKIYNHELLNPKMCN +LILKILGANTD-QEVLLRYLEADIRCAHKTGDLSN-LNHDIGVFKTKTS-EYILGVFVRN +ADFN-YVAKDLIGKVSKIVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A427GMV8_PSEST +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVTCAE +GLDEGKEAGSLFEQVGEAIS--- +>[subseq from] Serine hydrolase n=1 Tax=Arsenicibacter rosenii TaxID=1750698 RepID=A0A1S2VK58_9BACT +---------------SVTVSLAVQSLADQTSF-YHQADDRSPSASIIKLPVMVEAMEQVK +AGTFALTEKHLLTEAEKAGGSGVLQTYAAGSVTNLELVTLMITHSDNTATNILIHKL-GK +DAINRRIKALGLPQTQLNRIMMDTAA-VRRGIENYVTAREMNTLLTAIYRQTIATPALCT +QMLGILKQNTD-TLTIPRLIPETVAIAHKTGTLTY-VRGDAGIVYA--RRPFVMSVLVRG +TT--TEKAEQIIGDLALHCFTYf +>[subseq from] Beta-lactamase class A n=1 Tax=Thermoflexibacter ruber TaxID=1003 RepID=A0A1I2JAG5_9BACT +-nDLKKQIQAKFASIKGEFALAYKDLDNPSDTlFINAFTDFHAASTMKTAVMLEVFKQAQ +EGKFALTDSLTLKNESIVDSSAYSYSSLGQKRTIYQLVYEMITVSSNLATNMLIEIV-GA +ENVTQTLHSLGINQMKVLRGVEDSKA-FGKGMNNTVTAYDLALLLEKIAMNQVLNVKACE +EMRKILLNQKF-NDVIPALLPQEVKVAHKTGTIT-GVHHDSAIVYLPNGKKYVLVLLSRK +ME-DFDKGTKMLSEVSKLIYEY- +>[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. HAL1 TaxID=550984 RepID=G4FB08_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +-RAQALARALGVSTESFTQDYDHAFDAYEATGENVGTLRAFGDLLASLHGGTDLSAEQRQ +TLLAVMQRTSSGKRRLKAGLGEGINFAHKTGTQQR-RSCDAGIAERATEGPWVIVSCARG +PVA-VNAHERALASVGEA----- +>[subseq from] serine hydrolase n=1 Tax=Muricauda olearia TaxID=552546 RepID=UPI00101CF502 +---LEDKVHAQIDSIEGNVAVAFLNLSDPSDTlYINENEEFHAASTMKVPVMIELFKQKE +EGKINLNDSILLINESIVDGSSYSYNKINTQVALKDLMYNMITVSGNLATNVLIELV-DA +KKVTATMRDLGAENIEVLRGVEDQK-AYDLGLSNSTTAKDLLIIMEAIATNKAGTKEDCN +DMIAILKDQRF-NDLIPRDLPKNVEVAHKTGWIT-GVHHDAGIVYLPDGQSYVLVLLSKN +IQ-DSDKGTQQLADISKAFYDY- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Gemmatimonadetes TaxID=234665 RepID=A0A1Q7DNX2_9BACT +----RERLAARIARAASGVGVYYKRLTRPDSL-LLGANLRFHAASTMKVPVMIQIFRDAD +EGLLRLDDSLAVRAASLVDGSPFDYQRVGGTASIRELLDLMITRSSNLATNLLIDRV-GA +PRAQASARLLGAWSIQVLRGVEDGK-AYRAGLNNTTTARDLGALLAAIAQNRAASPSSCE +EMLRILGRQEF-NEGIPVGVPPGTRVAHKTGWIGGVVYHDAALVYPPSG-SYVLVVLTGG +IKED-SVAHNLVADLSRMVYA-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. FJAT-22090 TaxID=1581038 RepID=UPI00119FBE05 +--ELISKVQKLIKPSKGTWGIVLEDLNTGDKW-EYNEQELFYAASVIKVPIMVAVFRAVE +RLELSLSDLIILDKDEYVGGSGVLQHLTPGTLPLSDIILLMIIQSDNTATNLLIDLV-GV +ENIKQTMKEAGMEHSTFYNKLMLSKPN--PHGTNRIAAKDVGILLTKIAQGEIVSEQASK +QMIEIMKKQQM-RDCLPEKLPPAWEFANKGGWIP-GTRHDVGIFFVGDRK-LVATVLSEK +ED--DVLAKRILSQIGYEIYQY- +>[subseq from] serine hydrolase n=1 Tax=Thermoactinomyces vulgaris TaxID=2026 RepID=UPI0011077722 +-qKLSGSLDAWKKKSSGIWGIWMEDLNTGEKW-IWNEKQPFVAASMIKVPVMVAVYRAHA +LGKLCLSDRIELRREDRVGGSGVLQHLSYGTFTIQDLVTLMIIQSDNTATNLLIDRL-GK +EFVQETLLALEMTDTVFINRLHIVPAG--SNITNQITAKDMARCFRLLATGQAVSRDASR +KMVEILKKQQW-RNCLPGRLPPSWEMAHKTGWVNQ-TLHDGGILYIASH-SLILVVLSSG +LDH--HQAQREINHIGKWVYDAy +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F846B45 +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] Uncharacterized protein n=1 Tax=Tumebacillus flagellatus TaxID=1157490 RepID=A0A074LXM4_9BACL +-------LQKRLDAASGTFGASIYHFQSQERF-DSNADEVFFAASIIKVPVMAAVFDLAA +KGKLSLSETMALRTEDKTTGSGILFNLSTGLLSLRDLVVLMIIESDNSATNMLIDRV-GM +ETVQACMAEWGMEQTRIYNKLAVIPAN--LQNVNTITPRELTDFMIKLANGKIVSWKASR +EMIDILKQQKF-NDAIPSLLPPTYEMAHKTGWVSN-VENDTGLLYFPGHT-FAISIFTKD +VT-DKPATKRVMGEIGLDL---- +>[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus ratkowskyi TaxID=57028 RepID=A0A2W7RGK9_9BACT +---LQTTIQSQIDSIQGNVAVAFYNLSDSDSL-QINADEEFHAASTMKVPVMIELYKHQA +QGKLNLSDTIFLKNESIVDSSLYSYGKIGSVVTLNDLLYPMITVSSNLATNVLIELV-GA +RNVTATMRDLGAEKIQVLRGVEDQK-AFDLGLSNSTTAKDLMMIMKAIAENTAGTEADCK +EMIAIMKDQQF-KEIIPFYLPKEVTVAHKTGSIT-GVHHDAGIIYLPDGRSYVLVLLSKN +LE-DFVVGTEQLAGISKSVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_1_40CM_4_65_8 TaxID=1803456 RepID=A0A1Q7JX14_9BACT +-qRLQASIERTTRSISAAWGVYVKSLETGEEI-ALDADRQMETMSTIKIPLMVEAFEQIK +AGTFKLTDKYTFAQADSQPGTGTIQRLDPGAMTVKDLLTMMIIVSDNTATEVLYRMVGGP +DAVTRRMDALGLTKTRAMNIPSKWFARDGKNPFGLSTPREMGRLLEMMERGTLVDKASSE +LMLQMMRGQLY-RTRIPRYVT-GYRIPHKTGDFLPYVGDDVGMLEAQGK-TIIVSIFTGN +HFGSGEALENAIGLVAKDVADYf +>[subseq from] serine hydrolase n=1 Tax=Peptoniphilus grossensis TaxID=1465756 RepID=UPI0003031F03 +-dNLKNDIENLIKESSASISVTFCDLDNDEKF-SINGNKKVPSASMIKLLIMLTLLKKVE +LKEISLDEKTKLVEDKRVGGSGVLKDLSCDHFTIKELLTLMIIISDNYATNILIEKI-GM +DNINKLGKELNLLETSLERIMMDTDAQ-SRGLDNFTSSEDVFSVLKIIYEKSFLREDLSE +LALDILLRQQE-RDRLQRYLPEDLKIANKSGDLDF-LENDGGIFFTNSK-NYILVVLVNN +AD-SNVIAKDIIGKISLKIYN-- +>[subseq from] Serine hydrolase n=1 Tax=SAR202 cluster bacterium AD-493-K16_JPT_193m TaxID=2587841 RepID=A0A5N8YYK5_9CHLR +--RLESRLSHMIDGFAGVAGASVKDLSSGDGV-SVRGDEQFPTASTIKIHVLTQLLSRAE +RGELDLGKRIRLTPEMFGAGSGVIHYMENEPLSLLDIATLMIIVSDNTATNMCIDLA-GI +EGTNELLNKMGLKATKLRRKMMDSD-AIQRGDENVSTPNDLVEMLTLLHSGKP-SSKVAD +QVLHIIGKPKS--APINRGVPSGLVVANKPGGMER-VRCDAGIVFLDKN-PYALSIMTNF +GLEDGVKQEAFIVEVVKEI---- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A3S5EAG8_PSEST +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas seleniipraecipitans TaxID=640205 RepID=UPI000F0A593C +------------------------------------------------------------ +----------------------------------------------------------GP +QRVEAVANSLELKTDQLESDLDEAYRRYYQTGLNSATLVAYGQLLGKLASGELLSPESTE +LLYGIMGLDKYEAYRLEAGLDKALPFIQKTGTQQY-RACHVGVANPQDENALVIVACAAE +LDEN-DEAGKLFEQVGEAV---- +>[subseq from] Serine hydrolase n=1 Tax=Halomonas sulfidaeris TaxID=115553 RepID=A0A365TQ60_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +----ALARALGVSTESFTQDYDHAFDAYEATGENVGTLRAFGDLLASLHGGDDLSAEQRQ +TLLAVMQGTRSGKRRLKAGLGSGVSFAHKTGTQQR-RSCDAGIAERANEGPWVIVSCARG +PVA-VSAHERALAKVGEA----- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. OV322 TaxID=1882764 RepID=A0A1I1FM60_9BACI +--NLQKKIELHIAEFPGRISYKIES--EDQSI-QKDAGEGFQAASLIKIPIIMEGFRQIE +EGKIHLNERAEISDSDLAGGSGVLQALSKSGFTIEDMLTLMIIVSDNTATNMLIRKM-GI +NIINQTIASLNLKKTILGRYMMDFD-AIENGFDNYTCADDMVTCLRSIHQGSFLSGESRQ +HILSIMEKQQL-ISKLPAMMNNKVKVASKNGAIP-GAEHDSAIITRGDV--TVFAAVLTD +SLENEEDGRRIISQIGRYIYEE- +>[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter flavus TaxID=287099 RepID=A0A1I5CKS3_9FLAO +-qNLKQQIDSVFAETQGDFAIAFKELSEEKRTiLIDEHENFHAASTMKTPVMIEVFKQAE +AGRFSLDDSLLVKNESILDDSSFSYSLIGKKRSIKDLVVDMISQSSNLATNIIIELV-DA +KNVNKSMRELGAKNINVIRGVEDMK-AYEAGLSNSTTAYDLMLIFEALANGEAVNPESDK +EMLDILRLQQH-TDLIPALLPKDVKIANKTGWIT-GVHHDSALVELPDGRSYVLILLSRN +MK-DMEAGTQMLAGISKKIYD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus caseinilyticus TaxID=1503961 RepID=UPI00111377F8 +---------------------AIKHVESGQEV-IINGEKQFEMASVFKLPVLVALLTNAA +PRAVSLDTRMEIRQNDRVPGSGIIKELDEGLMTIRDLATLMIIVSDNTAADMVLHMI-GK +ENVNRKMKELGLENIVVRQSCWELLTMENTRQGNRATVTDTNALLEKIVTRRI-EVTASK +QIIDILSRQQY-RQRLPSLLPPATKTANKTGTIGT-VVNDAGILFLPDHKGTLIITVFSE +GNRTLAAGENVIAKIAKTAFDHy +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI00071AF38C +---VEGTIRDAFGDISGDNAVYVSPVDSDTEV-DFN-DQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Gemmatimonadetes TaxID=234665 RepID=A0A1Q6ZMN3_9BACT +--TLQTRVEARIAKTPARVGVYYRDLADRDSL-TVGAAARFHAASTMKLPVMIQLFRDRD +AGRLSLDDSLTVTNTSIVDSSPYQYKRLGQRVSIRDLIELMETVSSNLATNLLIAKV-GA +QRANATAHLLGADSILVLRGVEDGK-AYRAGLNNTTTARDLGILLAAIANVRAASGGSCR +DMLDILGRQQF-NEGIPAGLPPGTRVHHKTGWIEKVVYHDAALVQPPGDRGYVLVVLTAG +IQKN-DDAYALVRDLSRIVYE-- +>[subseq from] Uncharacterized protein n=1 Tax=Micromonospora arida TaxID=2203715 RepID=A0A3N9X069_9ACTN +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. PIC25 TaxID=1958773 RepID=A0A2A2DP10_9PSED +------------------------------------------------------------ +------------------------------------------------------------ +----TLARQLGVAPTQLRPSLGEAFEAYYATRLNSARLSAYGELLEALVNGKALGAEGSA +HLLGLMERVATGRKRIKAGLPTVAAFLHKTGTQRS-RFCDLGIVRTAGGDKRLIVAACTR +GDSSLARSETALRLVGQAVWQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=A0A0K9YMQ6_9BACL +-sKLEKTIQELAASVDGRVAVYIEW--DEGRI-GLNEQEAFPSASLIKIPIMLEALRQEQ +VGQTDLNTSLAIPAEERVGGMGVLANLSSDILPLRDLVSLMIAISDNTATNLVIQKV-TM +EAVNQLAARLGCQQTVLARKMMDTEA-VRQGRDNYTSAQDIGLFLKEIIVGNALDSSRKE +AAFQMMRQQQF-HTKLPAELPLDACFAHKTGELA-GIEHDAGILKIGKQ-YITMAVLTRD +L-ADEAAGREFIAKVGKAVFDTf +>[subseq from] Serine hydrolase n=1 Tax=Deminuibacter soli TaxID=2291815 RepID=A0A3E1NEQ5_9BACT +--SVAAHIGQLLLQHKGNFAVAFKDPASGKTL-FINEHALFHAASTMKTPVMMEVYQQAA +AGLLSMNDAVPVHNHSIADSSVYTYTKIGTNMRLYDLVYAMIIRSSNLATNIVIEKV-GA +PNVMRTMRHMGAQQIQVLRGVED-NKAFAAGLNNKVTAYDLMLLYEALANGRAVNAAAST +DMIDILLHQEF-NDIIPARLPAGVKVAHKTGNIT-GVHHDSGIVYLPDGRKYVLVLLSSG +WD-DEGDAIAAMAEVSRLLYS-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora arida TaxID=2203715 RepID=UPI000F5FB9F7 +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas seleniipraecipitans TaxID=640205 RepID=A0A1G7S9B8_9PSED +---LLARLQNIAAKQDGELGVYVKDLHSNLAV-TLHAEELWYMASGIKVPVAITVLRGVE +RGDWNLDTRLTLAADDFVDGAGSTNQYGPGAVSVRALLEQMIIYSDNTATDRLIRLV-GI +DAVNELVGELVPEGFEPITSLADVRRRYYSSNLNAARLTAFGKLLERLAYGEALGAEQTD +YLLGVMSRVKTGSKRIIAGLPKDARYAHKTGTQR-ARICDSGLIETSGTAEPVLVVACVR +GELSLAKAERTLRQVGEAL---- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas indica TaxID=137658 RepID=UPI000BABC27A +--RLLEELSRIDTDYPGEIGVFAKDLDSGLSI-SFRGEETWYLASGIKVPVAIAVLRDVE +RGEFTLDDRLRLEAYDYVDGAGETNHHPPGALSVRFLLEQMVIHSDNSASDRLIRLV-GI +EAVNRVVEELAPGGFQPITPLADVRRAYYATQLNSARLSAYGELLEALANGKALGAEGSA +HLMGLMERVATGRKRIKAGLPTVAAFLHKTGTQR-ARFCDLGIVRTADGDKRLIVAACTR +GDSSLARSETALRLVGQAVWQ-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium PASS1 TaxID=2015579 RepID=A0A257DPU1_9SPHN +-eKLRNDVDALWKKFPGRAGIAIYTPFSDDII-GRRQTERFPQQSVSKLWVALAILEQEA +AGKLSLDKQVRVSRDDVVVSQPIKRYLSGKDMPVSELLAHAINASDNLANSVLLRVAGGP +QAINQMLDRRKVQSIRFGPGEVLLQSSYLASPLDGAAPGTIVLALKRF--GERGPNDPGA +KLLKLMAGTYTGKSRLRSGLAPGWSLAHKTGTGQSTAVNDVGVMKAPDGCRYQVAVMIAE +TRAGKDVTNGLMQNVARAVVRH- +>[subseq from] Class A beta-lactamase n=1 Tax=Paenibacillus sp. FSL R5-0490 TaxID=1920424 RepID=A0A1R1ENV1_9BACL +-hTLKAEILTLASCCEGRVAVYIHT-E-DGFI-EKDADAVFSSASLIKVPILLAGLSQAE +KGLLQLEEEVEVTASARVGGSGVLQAMARDLIKVTDLMTLMIIVSDNTATNLIIELL-GI +EKINQLFKSLGFDHTSLNRKMMDFE-ALKNGIDNTTTARDMAYGLKALAEQKLLSGKYTE +KALYILENQQFKNKLANTIDEEKVMVANKTGELP-GIEHDCAIFTHKGK-TVCAAVLVDR +LQN-QAAGKEVLSAIGSRI---- +>[subseq from] serine hydrolase n=1 Tax=Halotalea alkalilenta TaxID=376489 RepID=UPI00069360A0 +------------------------------------------------------------ +------------------------------------------------------AAI-GP +LRVDAVARALGVERAELEDDIDAAYADYYAQGDNSAALADVARLFEGLVEGELLNSEHRA +LLYRLMKIDRYEAYRLEGGLDEATEFIHKTGTQRQ-RACHAGVIDPSDPERAIVVIACTQ +DMDEASPSEALLERVGASI---- +>[subseq from] Peptidase_M14 domain-containing protein n=1 Tax=bacterium TaxID=1869227 RepID=A0A2W4U106_9BACT +--------ARIAQEAPAEVAVALVDLATGLRL-GIGDTVTMHAASTMKVPVLLELIRQVE +AGRLSLDARIPVVNESIADGSTYAYDAVGQERPIRELARRMIVRSSNLATNNLISYV-TP +DSIARTLARLGAPGMRVLRGVEDGP-AYARGMNNTTTAAAFARVLEAIARCEEVSRAGCE +EMIDILAAQEF-NEMIPAGLPPGTRVAHKTGWITR-IHHDGGIVFPPGREPYVLVVLTRG +FD-DKERSARVGADISRAVWE-- +>[subseq from] Serine hydrolase n=1 Tax=Psychrobacillus sp. AK 1817 TaxID=2303505 RepID=A0A5J6PM77_9BACI +--ELISKVQKLIKPSKGTWGIVLEDLNSGDKW-EYNEQELFYAASVIKVPIMVAVFRAVE +RLELSLSDWIILDKDECVGGSGVLQHLTPGTLSLSDIMLLMIIQSDNTATNLLIDLV-GV +ENIQQTMKEAGMEHSTFYNKLMLSKPN--PHGTNRIAAKDVGILLTKMAQGEIVSEQASK +QMIEIMKKQQM-RDCLPEKLPPAWELANKGGWIP-GTRHDVGIFFVGDRK-LVATVLSEK +ED--DVLAKRILSQIGYEIYQY- +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=UPI000C1863E1 +----EKIIQDLLHETPYKVHLFVKNPKNEQFLfSHQIGEAFSSASIIKVPILLAALAYVE +KYSISLHSSLPISPADWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM +EFLNDYFRQIGLQETLLQRKMMDVER-LAMGLDNFTSAWDMAHLFTRIYQQDLLAPPYNR +LVIDILNRQRA-HEGLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYSNSID-YLIGVFITN +VTEN-ELARQLIGRFSKVVYDH- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7AE676 +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGGLLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE +GLDESKEAGSLFEQVGEAIS--- +>[subseq from] Uncharacterized protein n=1 Tax=Micromonospora inaquosa TaxID=2203716 RepID=A0A3N9WKC7_9ACTN +---------RVVADANLNAGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQAFLDDGVLVTPDDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI00137C3DDA +---VEGTIRDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATIYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI0007B6984F +---VEGTIRDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATIYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] Beta-lactamase n=1 Tax=Thermobrachium celere DSM 8682 TaxID=941824 RepID=R7RQN3_9CLOT +---------DYIDRLNCSVGVYYKELETQYMF-EYNSDKIFPSASTIKVPILLALFNKVL +KGEIDLNKRIKIQKDYTVSGAGIVYLLDENNYTLLDLAKLMIVLSDNTATNIIIDLL-GF +EYINKYFKEIGLNETILQRKMMDFDRK-RLGFDNFTSARDLGLTFYKLCKKEVLNPYYCN +LAIEILKEQKL-KGGLDRYLGNKYEIAHKTGELNN-LEHDCGIVFKDHK-TFIVVILTEG +EEN-------------------- +>[subseq from] Uncharacterized protein n=2 Tax=Aneurinibacillus aneurinilyticus TaxID=1391 RepID=U1WRZ8_ANEAE +-qKLREDVERAVSKVDGKVSVAIEA--DKEHI-SINANDPLPSASLIKVPIMIEAYRQAQ +EGKLSLVSEYSLLPEDRVGGMGVVSHLSPELLTLKDLISLMIIISDNTATNMVIRKV-GI +NTVNRLAADLNCGQTVLARMMMDHE-AVKLGKDNITSANDIVRFLKEIVEGRMLNEENKK +AAYDTLLNQQF-NTKLPAGFSLNATLAHKTGELP-GTEHDAGVFYINGK-HTYVAVLTTE +LS-DNASGQRMIAQVGKLVFDY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriia bacterium 35-40-5 TaxID=1970579 RepID=A0A258KFC3_9BACT +---LLQDIKTELGKQAGFFALAFEDLQTRHQI-LWNADTEFHAASTMKTPVMIEVYKQVA +AGKRSLQEPVLVKNQSIVDGSDYQYTQIGTRIPLADLVYQMIIRSSNLATNLIIEMV-DG +KKVTQTMRGLGAKKIQVLRGVEDQK-AFDAHLNNTTTAKDLRLIYAKMAEGRIIDKNACA +DMIRILEDQTD-REIIPALLPANVKVAHKTGYIT-GVHHDSGIVFLPDGKKYVLVLLSKN +LT-DNAAAVASMAKVSEMIYRY- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6GR62_9BACT +-----GELERLTAESKARAAVALHDFESGFRF-SLRGDRWFHAASTIKVAVLLAVFRAVD +QGRLGLSDSLHVRNRFLSAGSPFRYRAIGRTAKISALAEGMIRASSNLATNLLLDLL-GV +EYARRVLRDAGISGVELRRGVEDH-AAHEKGINNEVTADGLLTLLSAL-RGDFLSSESKE +QAIHILLGQRF-KSMIPAGLPAHATVAHKTGEIST-ACHDMGIVYLPERQPYLLAILTEF +DA-EQDGRRETVAAISEVIH--- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus terrae TaxID=1914933 RepID=A0A429XDS2_9BACI +--TAEMQIKKLIDQAGGDWGIMVEDVENDISW-GYRTVASFPAESVIKIPIMAAVFSAVE +NKKLKLCDHVKVHLDDRVGGAGALQYLTPGILSVYDLLVLMIVQSDNTATNALIDLV-GI +EHIQQTLSETGMKDSSFQRKLMVYPA--QSDLQNTVTVADVNLMLRKLIDGQLVSRHACE +QMIQILKWQQF-RNGLPSKLPPKWELAHKTGWDTD-RQHDVGILFTGNRT-MIVSVLSDN +VS--SETAWNVMGDIGKIIYDY- +>[subseq from] serine hydrolase n=1 Tax=Arenibacter sp. AK53 TaxID=1406873 RepID=UPI000A36CFFF +-eDLAKKIHTQIDSIDGTVAVAFYSLSKPKDSlLINVDEKFHAASTMKVPVMIELFKQAS +QGKINLQDSIVLKNESIVDDSLYRYNQIGSKVALKDLMHSMITISSNLATNVLIELV-DA +KMVTASMRDLGAENIEVLRGVEDLK-AYEKGLSNSTTAKDLMVIMKSIANNSAGTPKDCE +AMITILKDQQH-KSLIPFYLPEAVKVAHKTGSIT-GVHHDAGIVYLPDGNAYVLVLLSKN +LK-DFDKGTEQLARISKTLYDY- +>[subseq from] Beta-lactamase n=1 Tax=Pediococcus acidilactici D3 TaxID=1306952 RepID=R0GCN6_PEDAC +--TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDRDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A521TC22_9BACT +--SAKAEIERIIALSGAEVSVIYRPVGGHGEI-LINPDTTYHAASTMKVPVMIELFRQVD +AKLIKLDDQIPVSNHSIVDGSEYTFLAIGKTMSYRDLCEQMITISSNLATNVLMEKL-GV +ENIRATVAKLKAPGMNVLRGVEDQK-AFDKGMSNQTTARALMTLLTAIANGAAGSKSSCA +EMQAILKRQKF-NDGIPAGVPAEIAVAHKTGTIT-AIHHDAAIVYAK--EPYILVVMTRG +MP-DEKKSDLLIAEISRIIYR-- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI0008786AD5 +--TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTIPIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] Beta-lactamase n=1 Tax=Pediococcus acidilactici NGRI 0510Q TaxID=1229281 RepID=K9IBP6_PEDAC +--TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTIPIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] Zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=A0A5R9BD69_PEDAC +--TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTIPIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] Serine hydrolase n=1 Tax=Caldilineaceae bacterium SB0662_bin_9 TaxID=2605258 RepID=A0A6B1DQT3_9CHLR +-sQLQDRVRDGLADCPGVAGFCLQDLATRDTM-GWHEQEVFPVASTIKIPILVTLLARAE +KGELDLQERIAITPAVLVPGSGVLTYLEGPLLSVLDIAQLMIMVSDNTATNLCIDWA-GM +DATNELMESLGLSQTRIRRKMQDHES-VARNEENVSTPADAVGLMRALYESRP-SSAVAE +QALAILKKPNRG--PIERAMEPGVAVSNKPGGMER-VRCDAGIVWLQRH-PYALAIMSKF +GMENYRHENRLVAAV-------- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7H097_9BACT +--TLRARLEARIAQAPAQVGLYYRSLARPDSI-LIGANLRLHAASTMKVPVMIQIFRDAD +AGLLELNDSLTVHTASLVQGAAFTYAVVGRNRSVRDLLELMITRSSNLATNILIERV-GA +SRAQASARSLGAWSIQVLRGVEDGA-AYRAGLNNTTTARDLGVLLGAIAAGRAASRAACD +SMLVILGRQEF-NEGIPAGLPPGTRVAHKTGWIGEVVYHDAGVVYPPHGGSYVLVVLTGG +IKED-SVAHNLVADVSRMVWE-- +>[subseq from] serine hydrolase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=UPI0012CFB711 +--SLEEEVTEKIRRLPGKTGFYYENLVTGERA-AYHEDERMMAASVIKLFVMTEAFVRFE +EGTLSTDRIIRMKREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTATNVLIDLL-GI +EEINRTIRRMGYRDTVLQRKMYDTEKS-KRGIQNYITAAETGRLLREMYQGRLVSRQASE +KMISILKNQQL-CSKIPFYLQEEPEIAHKTGEDC-GITHDVGIVYAKQ--P-FIVCYCGN +DT-DTPAYERVMAETSLWLY--- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. FJAT-29814 TaxID=1729688 RepID=UPI000835D834 +---LKAKIREELVGFRGRIGLAIEA--GDECI-YFNSEEVFPSASVIKVPILLAGLKQAE +EGYVNLDQLTVITE--RVGGSGVLQSLSSLALTIKDLLTLMITVSDNVATNMVIDLL-GI +EAINQEMERLGLKSTNLNRKMMDFA-AIQRGFDNVTCPSDMVKCLKAINEGAFLSAESKE +IALSIMHAQQF-LDKLPAMMPDRVFIANKTGGLPN-VEHDCAIFKYNGKT-AYAAVLTDQ +LT-DAYEAKLVISRIGKHVADY- +>[subseq from] Beta-lactamase n=1 Tax=Parabacteroides distasonis TaxID=823 RepID=A0A3D9A3X0_9BACT +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSA----DHTNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] serine hydrolase n=1 Tax=Nonomuraea sp. FMUSA5-5 TaxID=2720023 RepID=UPI001439A137 +------AFDQLFRAAGVTGWLYAADVDTGHDV-GHGADEPMPTASMFKVPLLVALCRRAD +AGLLDLTERVTVTAADRVGGPTGLSSMLDDVISLRDLAYLMIALSDNTAADKLLGRV-GF +EAINTMLDAFGLEGTRVVQGSGEMLGVLDPSRTNRSTPREMVRLFGMIWRDEAASPESCA +WMRGVLNMQVW-PHRMASGFPDDVAVSGKTGTMPT-LRCETGVVEYPDGGRYAVSVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora inaquosa TaxID=2203716 RepID=UPI000F6013B8 +---------RVVADANLNAGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQAFLDDGVLVTPDDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7V1U9_9BACT +----------------ERLGIAFYDAETTLQW-SYNADLAFHAASTMKLAVLLAVFRQYT +RGELTLDEPVHVRNKSIYDRKPYMYDHLGRTMSVKQLAYYMITCSSNFATNLLVDVV-GV +PVIQTALDELKIDGIRVLRGVEDH-GAFEAGLNNEVTANGLLKLLRLVAEGKAYGEEASA +QMREILLDQRY-KSGIPAGLPQAARVAHKTGNIST-VHHDAGIVYLEGRKPYVLVILTQF +SSE--TGRTTAVADVSRDIYE-- +>[subseq from] Uncharacterized protein n=1 Tax=Firmicutes bacterium CAG:110 TaxID=1263000 RepID=R5EIJ3_9FIRM +-nDLASRLNAVMDAFPAKTALYCVDLTTGTPIvAIRENTRVVSASTIKVSILCCALQDVM +DGKLSLDQPLAIAPGDFCSDTEVFEPYRQDGASFWEMLYWMIVSSDNTATNTVISLL-GY +DHVNQYCRAIGLTQTSLQRKMLDFQ-AIAEGRNNYTSPADLYRVFSRLYHGEILNKALRE +VAFDFLSRCRS-TDALQRYIPDAVTVLHKPGGLDH-LNHDVGIFLTDDR-PYYLGIFTWD +GPDGQPQQNRLIGQLSRMIYDA- +>[subseq from] serine hydrolase n=1 Tax=Microbispora rosea TaxID=58117 RepID=UPI0004C3CB0B +--------ERVFRSAGVTGWLHAVDIDDGREV-GLRADEPVVLASVFKVPLLLELQRQAE +RGLFDLTERVGVPAADRTGGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLARV-GR +EAVNALLDGLGLTATRVVQNCREMLTALDPAVGNRSTPREMTRLLAMIWRDEAAGAASCA +AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +FGQNQPRADAAIGAAARMAIDQ- +>[subseq from] Beta-lactamase class A n=2 Tax=Pseudomonas seleniipraecipitans TaxID=640205 RepID=A0A1G7SAZ6_9PSED +------------------------------------------------------------ +----------------------------------------------------------GP +QRVEAVANSLELKTDQLESDLDEAYRRYYQTGLNSATLVAYGQLLGKLASGELLSPESTE +LLYGIMGLDKYEAYRLEAGLDKALPFIQKTGTQQY-RACHVGVANPQDDNALVIVACAAE +LDEN-DEAGKLFEQVGEAV---- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7JAU9_9BACT +--SLSAAIAARIAQTPARVGVYYRDLATGDSL-TVGSDVRFHAASTMKIPVMIQLFRDRD +AGLLSLDDSITVTNTSIVDSSPYQYKRAGAGASIRELIELMETVSSNLATNLLIAKV-DA +KRANATAHALGADSILVLRGVEDGK-AYRAGLNNTTTARDLGILLAAIANETAASARSCR +DMLAILGRQHF-NEGIPAGLPAGTRIYHKTGWIGQVVYHDAAFVEPPGGRGYVLVVLTGG +IQT-DDDDHALARDVSKLVFE-- +>[subseq from] serine hydrolase n=1 Tax=Bacteria TaxID=2 RepID=UPI00056F2F4E +------KILDILNGIPGKTGFYYKNLTTGEKW-EVRSEEPMIAASVIKIPVLAEVFAQLE +AGTADKNELYRIREEDKLPSCGALNMHTGLEVTLEDLYTLMIILSDNTATNLLIKKF-GM +ENINRRMRSLGLNVTTVNRLLFDAGAS-AAGRENRICAKEIGLLLEKMYRGELISPKASQ +EMISILMNQRL-NGKMPFHFKGKVKIAHKTGEDG-GITHDVGIVFAPQP--F-VACFCSN +ET-DVPLFERAIQDITKLLYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Eremiobacteraeota bacterium TaxID=2052317 RepID=A0A2W5X8Z2_9BACT +--ELQLQLASISLHAPGHVAMEIKDLGSGAIS-SVNARASMPAASTIKIPVMVEVFRQLS +NGRFDFNTTVGLRRSDKDWGSGSLCNRAGTRYSVLRLLKAMITVSDNTATNMLIRLV-GR +QNINDDMLSIGLQHTRLSDYIRSQGDDIR--YALRSSPADMVMLLEQMAGNELIDRWSSR +EMISILEGQRH-NGLLPEPLPMGLPIAHKTGTLHD-TLNDVGIVFADPQ-PYVIAVMTTN +LP-SLSAGRRFIRGVSRLAYDQ- +>[subseq from] Serine hydrolase n=2 Tax=Streptosporangiales TaxID=85012 RepID=A0A1V0A8N3_9ACTN +------AFDQLFRAAGVTGWLYAADVDTGHDV-GHGADEPMPTASMFKVPLLVALCRRAD +AGLLDLTERVTVTAADRVGGPTGLSSMLDDVISLRDLAYLMIALSDNTAADKLLGRV-GF +EAINTMLDTFGLEGTRVVQGSGEMLGVLDPSRTNRSTPREMVRLFGMIWRDEAASPESCA +WMRGVLNMQVW-PHRMASGFPDDVAVSGKTGTMPT-LRCETGVVEYPDGGRYAVSVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] Serine hydrolase n=2 Tax=Kribbella soli TaxID=1124743 RepID=A0A4R0H7A3_9ACTN +------ELESLRERKPLGIGIYVKRLTTGEEA-AVRADVVFETQSVIKLAVAIRCYQLAD +DGRLDLDERIRVTRSDIVGGSGVIRYFQEGLPTVRDLLTAMIVVSDNSATDLLLARVGGV +ADLNAWLAASGYTQTRMAQSLLDADRG---L-PGQMTPREAGRMLESIEHATAVSGKSSA +ELRGALRQQQLGERRLPQFVE--HPVGHKTGDNPPWDANDVGIIYSPSG-PIVVAVFAND +LGGVYEQEEDRIGRIGRVIVDHf +>[subseq from] class A beta-lactamase n=1 Tax=Muribaculum sp. TLL-A4 TaxID=2530390 RepID=UPI00143DF3D7 +---LKEKLTQYIADKNARIGIALL-VNGRYSV-SVNGDDAFPMLSVYKFPIAMAVAEYCR +MRDIDFSDSCLVTAGDLHRYSPMLQKYAEVDITFDELLTYALQQSDNNASDILLNRIGGA +TSANEYVSGIGIEGVTIKWSEDDMHIDMSRCYENSATPLAMAKLMWTFDFQ--CNDTLSK +RIKQLMESCETGQGRLAKPLEANAVIGHKTGTGFVNAVNDAGYVHLPDGTRYSIAVFIAD +SHYDMEHTEDIIADISEMTA--- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. N3536 TaxID=2666127 RepID=A0A6B8K739_9BACI +--ELISKVQKLIKPSKGTWGILLEDLNTGDKW-EYNEQELFYAASVIKVPIMVAVFRAVE +RLELSLSDLIILDKDEYVGGSGVLQHLTPGTLPLSDIILLMIIQSDNTATNLLIDLV-GV +ENIKQTMKEAGMEHSTFYNKLMLSKPN--PHGTNRIAAKDVGILLTKIAQGEIVSEQASK +QMIEIMKKQQM-RDCLPEKLPPAWEFANKGGWIP-GTRHDVGIFFVGDRK-LVATVLSEK +ED--DVLAKRILSQIGYEIYQY- +>[subseq from] Uncharacterized protein n=1 Tax=Sporosarcina globispora TaxID=1459 RepID=A0A0M0G7G7_SPOGL +-nTLKAEILDLASCCEGRAGVYVHT-EDG-VI-AANADDVFSSASLIKVPILLAGLSQAD +KGLLHLEEEVEVKDAARVGGAGVLQAMSKDLFKVIDLMTLMIIVSDNTATNLIIELL-GK +EKINQLIKGFGFQYTELNRVMMDFK-ALKNGIDNTTTARDMAIGLKALAEHSLLSGKYTE +RALHILEKQQYKNKLANTMDTEKVKVASKTGELP-GIEHDCAIFTRNEK-TVYAAVLVDQ +LY-NQSAGKEVLSSIGRRIYQY- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium 13_1_40CM_66_11 TaxID=1805195 RepID=A0A1Q7E875_9BACT +--SLRARVEARIAQAPARVGLYYRDLTTGDSL-TVGSDVRFHAASTMKIPVMIQLFRDRD +AGLLSLGDSVPITNTSIVDSSPYQYRGLGQRASIHDLIELMETVSSNLATNLLIAKV-DA +KRANATAHALGADSILVLRGVEDD-KAYRAGLNNTTTARDLGMLLAAIANARAASPASCK +EMLAILGRQHF-KEGIPAGLPPGTPVYHKTGWIGQVVYHDAALVEPPHGGRYVLVVLTGG +IQKD-EDSHALVRDLSKLVFD-- +>[subseq from] Putative beta-lactamase n=1 Tax=Algoriphagus machipongonensis TaxID=388413 RepID=A3HV13_9BACT +----KELVSAQIASIQGDVAVAFINLSDPSDNlMIQADEEFHAASTMKVPVMIELFKQEE +EGKLNLDDSILLVNESIVDGSSYSYNKIGTKVSLNDLMYNMITVSSNLATNVLIELV-DA +KKVTATMRDLGAAKIEVLRGVEDQK-AYDLGLSNSTTARDLLEIMEAIALNEAGTQEDCQ +EMISILKDQKF-NEIIPFHLPEGVSVAHKTGSIT-GVHHDAGIVYLPDGRSYVLVLLSKN +LA-DFDKGTEQLAGISQTIYEH- +>[subseq from] Beta-lactamase enzyme family protein n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=A0A1C4U2Y8_9ACTN +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPQDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=A0A1S2SVL9_PEDAC +--TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGGLSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI00066CC434 +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSRLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] serine hydrolase n=1 Tax=Aliifodinibius halophilus TaxID=1736908 RepID=UPI0013EAB784 +---LKSKIKKQLKKVKGDFAVAFKNLSDTSQAiYINEREKFHAASTMKTPVMIELFNQAE +NGRFSLDDSITVKNESIVDSSRYEYDMIGKKRSIRQLITDMITMSSNLATNILIQKV-GA +HNVTQTMRSYGVDSIMVLRGVEDIK-AYEKGLSNRTTALDEAIIYEQLGKGQAVSREASE +AMIEILIEQHF-NEMIPAQLPESVVVAHKTGWIT-GVNHDAGLIILPNGHKYVLVLLSKN +AP-NRERVQSAFADISGDIY--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. WAC 01420 TaxID=2203203 RepID=A0A428ZCY1_9ACTN +------------------------------------------------------------ +---------------------------------------------DNTAANLLLTTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIVHD- +----------------------- +>[subseq from] Serine hydrolase n=2 Tax=Lentibacillus salicampi TaxID=175306 RepID=A0A4Y9A9H0_9BACI +-eQLEADVHSLMLDFDSPVGLVIKE--GNDTI-NINEDVPMPAASVIKIPIMMEAFRQAE +NGLLDLSQNMEIPTDAIVGGSGVLQFLSERVMSLLDFLTLMIIVSDNTASNLALEQT-GI +ENVNNLCRDLECHHTEVQRYFMDMKAA-ESGFENTTTAGDMVKFLEEIASPKLLTKKSAG +HIFDIMTGQQL-TSKLPAYHANDVVIANKTGELAI-AQHDVGIFKYQDKT-VLAAVMTDR +IT-DHIAIQQTIARIGKAIMSY- +>[subseq from] Beta-lactamase enzyme family protein n=1 Tax=Micromonospora cremea TaxID=709881 RepID=A0A1N6AMH9_9ACTN +------------------SGVTVRDLSGDQQI-AVNGALRPKAASVIKLWILVELLRRVD +CGRVSLDDGVLVTPADVVGGTGQLQFETPQVVTLRRLAQYLIKYSDNIAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAAL-RGEENYTSPDDVVSLLGAVWEAEILSPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSE-TAVAFLTAG +PM---DTGDETVRRMARTVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Halomonas urumqiensis TaxID=1684789 RepID=A0A2N7UQS7_9GAMM +-qRLEARLETLEDAFEGELGVHVRVLGSDERF-GFRDDERWYLASLIKVPVAIELMSRVE +RGEASLATSLTLAESDYVDGAGPTNWSPGTSLRLEELLEPMLTVSDNTATDMLIRHL-GL +EAVNRRAALLAGVGFGPITTLVDVRRAYYASGLNAGRLDAYANLLAALGEGRALGPRATA +ELLSIMQATTSGENRLKAGIGPEPRFAHKTGTQHR-RACDAGIVLPEQGQRIVVVACTRG +P-LETTLHERALAAIGVAL---- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacterium sp. TaxID=1872119 RepID=A0A2G4JHK8_9BACT +--SLESRLRQVRDEVDGRLAVYVENVATGERV-AIDADSPYETFSVIKVPLMATVLERVR +DGRLSLSDRITLTAGQRRIPSGVLYALDAGLPTVKDLLTLMIVISDNEATDALGDLV-GR +EEVTRAMARLGLPNTRLRFSDLEWDREETGLYFGRSTARETGRLFALMAKGELVSKEASA +LMVSILKRQQV-NNRFPRYLGADVEVAHKTGDGQPWVANDAGILWVKGT-PIVLVAFAGH +HRGTTEEIHEAEARIAAIVADHf +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=A0A328NCD5_9ACTN +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWVLVELLRRVD +CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7U3X5_9BACT +-eKLRARIEAVDRGLDGVLGVSVKDLKGGMTL-DVRPAEPFPQASSIKLAVLYELYRQAE +EGRVDLGEL-TRPPLPRVRGGGVLQELGNQVLTWRDVAVLMMGWSDNAATNVLIDRV-GM +DAVNRRLDLLGLRATRLRRKMMDLEAARRG-DENVSTPAEMRQLAETMYAGAGLSKERAR +DMMAVAAVPKE--SPFREPLPEGLVVADKPGSLE-AVRCVTAIVDLPGR-PYAVSIMTTY +LRRD-ADGAAAIREISAALYETf +>[subseq from] Uncharacterized protein n=1 Tax=Bdellovibrio bacteriovorus TaxID=959 RepID=A0A150WBR6_BDEBC +------------------------------------------------------------ +------------------------------------------------------------ +-RYEAFAKLIQVPVSELKTSIEEAFEKYYARGLNSTTLRSFGSLLEKLARGQVLNKAHTA +LVLKYMQEMKTGENRLKAGLPKDVVFAQKTGTQV-ARMCNVGIAASKKKQQKTVIVACAE +KYLDQAGAEKVLKKMADALTE-- +>[subseq from] Uncharacterized protein n=1 Tax=marine sediment metagenome TaxID=412755 RepID=A0A0F9VTJ3_9ZZZZ +------------------------------------------------------------ +------------------------------------------------------------ +----ALARTLGVTDTFTQPDYDRAFDAYEATGENVGTLSAFGDLLASLHQGHALDAEHRQ +VLLDVMRRTSSGKQRLKAGMGEDISFAHKTGTQQR-RSCDAGIAERANVGAWVI-VTCTR +GPAALSAHERAMASVGEAL---- +>[subseq from] Serine hydrolase n=1 Tax=Echinicola sp. LN3S3 TaxID=2591634 RepID=A0A514CMB5_9BACT +--ELHQAIDSRLNKEEGDFAVAFRSLGADPVTlLINEKETFHAASTMKTPVMIELYKQVA +LGTISLDDSVKIVNESIVDGSPYRYSKIGQFSTYRELNFEMITMSSNLATNILIDKL-DA +KKVTETMRSLGAKDINVLRGVEDLK-AYEQGLSNTTTAHDLMLIMEAIAEGKAVSKEASL +AMFEVLKAQHF-NEIIPGQLPEDVTVAHKTGSIT-GVRHDSGIVELASGKRYVLVLLSKN +LKAP-EEGIQAMSDISKLLYD-- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus borstelensis TaxID=45462 RepID=UPI000F0829D4 +-kSLQEKLETIIAAAGGQWGVVVEEINGSFYW-EHNTTQTFAAESIIKVPIMAAVFDAAS +KGNVRFDQAVRMKQTDQVAGSGVMQHLTPDAYPVYDLITLMIIQSDNTATNMLIDLI-GE +DQVRLTMAELGMHDSCYSRKLMLYPAD--SPPNNMITAGDIARMLKRLATGTFLGEHACR +QMIGIMKKQQV-RNALPARLPAVWEMANKTGWDT-GRQHDVGILFAGGK-AYSLTALSEN +APPD--ASLQAMAAIGYEVY--- +>[subseq from] serine hydrolase n=1 Tax=Clostridium estertheticum TaxID=238834 RepID=UPI0013E93DD1 +-------ILDFMKDKNLKYSILIKDLNSDKSC-CINEEEVVPSASIIKLFIMAKTFQLVS +NGELNLSDRISINKEERVPYSIIYVLDDRNTYTIRDLITLMIIQSDNTATNQLIHML-GI +ENINKFIGELGFKNTILKRKMMDFDARVL-GMDNYTTAHDVAKLLELMDKGQLISKTYSD +MMIKITQMQLD-NSMMRINLDEELIVAHKTGDLPN-IKHDVGIVYARHK-HYIFNMLTWD +ATCD-NYARDIIGKVSKISYEY- +>[subseq from] Serine hydrolase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=A0A2W5IMW9_VARPD +------------------------------------------------------------ +------------------------------------------------------------ +QRAEAVRRALELPPDALRTDIDAAYAGYYAEGRNSATLVGYGAMLERLVRGELLSRTSTE +RLFQAMKFGTRGNYRLEAGLPKNLRLIHKTGTQHQ-RACHMGVVQPQDGDATVVAVCAAE +LD-EQRAAGRLFEAVGRAIA--- +>[subseq from] Serine hydrolase n=1 Tax=Luteimonas terrae TaxID=1530191 RepID=A0A4R5UFH5_9GAMM +--TLDHHVRAIDARLTGELGVHVQRLDGGTQY-GFRADEVWYLASGVKVPIAIAVLREIE +QGWLTLDTQVTLRADDFVDGAGGTNAHRAGDLTIAWLLEQMIVHSDNTASDVLIRTV-GL +GQVNTVASELIARDVRITSL-ADVRRSYYATHANSATLRDYGHMLGALQAGDALGPEGTR +YLLDVMARVQTGKQRIRAGLPTGARFAHKTGTQYR-RICDSGIVTVPARAPVQVVVAACV +RGAGTAASERALRELGAALT--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A4Q3V9K9_9BACT +-dSLRNKISRTAGSINARVGVSMLLLESGDTL-SYRAEERFPMMSVYKLPIAIAVLKELD +RGTIFMEKYLLIQKDSIQTGEEEMYAFPDRKITVGQLLTLMLVQGSNTACDLLLSMMRGP +SGIQPYLDDLDIHDMAITNTEREINANPILKDNNWTTPNELVRLLTIAYSSDYLSTKNHD +FLWDKMTETVTGPDRLKALLPKNTLVAHRTGTG--------------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Pseudomonas stutzeri B1SMN1 TaxID=1212549 RepID=S6JRL7_PSEST +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE +GLDEGKEAGSLFEQVGHAIS--- +>[subseq from] Serine hydrolase n=1 Tax=Paraflavitalea soli TaxID=2315862 RepID=A0A3B7MPC5_9BACT +--QLKQAITTELAKNEGQFAVAFSDPATCTTL-LINADSSFHAASTMKTPVLIEVYKQAA +AGTLSLTDSVLVKNESIVDSSTYSYTLIGTKRTLYDLVYDMIIMSSNLATNIVIEKA-DA +KKVTQTMRDLGAKDIQVLRGVEDSK-AYQQGLNNTTTAYDLMVIFQKMAAGETVDSAASQ +AMINILLDQHF-NEIIPAKLPKDIKVAHKTGNIT-GVQHDSGIVFLPDGRKYVLVLLSKG +IK-DEKAAVASMARVSEMIYQY- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI0007F0071B +--TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTIPIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGT-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] serine hydrolase n=1 Tax=Flavobacteriaceae bacterium MT2-5-19 TaxID=2607999 RepID=UPI0011EC6C4A +------HIRTQIDAIDGEVAVAFQNLSDDDRL-LIHGDETFHAASTMKVPVMIELFKQQR +EGLIDLNDSILLVNESIVDGSPYQYNNIGQKMTFYDLLYPMITVSSNLATNVLIEWA-DA +KKVTATMRDLGAQNIEVLRGVEDIK-AYELGLSNTTTARDLMIIMQAIAEHKAGSPADCK +EMLRILKDQRF-NEIIPFYLPDSVEVAHKTGSIT-GVHHDAGIVYLPDGRSYVLVLLSKN +LE-NFEEGTEQLAGISKTIYEY- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus oceanisediminis TaxID=665099 RepID=A0A2V2ZPF7_9BACI +--KLKAEILELANRCEGRVGAYIQT--EEGII-EENCSKVFSSASLIKVPILFAGLSQTE +NGLLQLEKEVQINNAVRVGGSGVLQSMSKELMKVIDLMTLMIIVSDNTATNLIIDLL-GK +EKINGYMKNIGLKNTELNRKMMDFES-LKKGIDNTTTARDMAFCLESLAERSILSEENKA +LARRILDGQQYKNKLANTVDQEKVQVANKTGELP-GIEHDCGIFTGNGR-TVYAAVLVDQ +LKN-QAAGREVLSFIGSRIYR-- +>[subseq from] Serine hydrolase n=1 Tax=Bryobacterales bacterium TaxID=2026791 RepID=A0A350UGI2_9BACT +--------GKLKRETGGDAWWYAKHLESGREE-AYRADERVRTASTIKLPIMAAAFDLAE +RGELKWDERITLRREDIVSGSGILQEMTGGEFRVDDLVKLMIVVSDNTATNLVLERV-GG +DRVNGFLEGLGLAETRTLRRIRGDGTENARFGSGVSTSREMGRLAAMLHQGRVVSRAASR +AMVEILKRQQY-KDCIGRRLGSGVVVASKSGALD-ALRSDVALVTGKGGT-FVLAITVDG +MKSEDNLGSIAIAEMAKALV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Dyadobacter koreensis TaxID=408657 RepID=A0A1H6Y8B8_9BACT +--KLKQKILAELHKYKGTYAVAFKDLSSGDEL-LINEHENFHAASTMKTPVMIEVFKQAA +LGKFALTDSVTIKNESIVDGSLFSYRQIGQKRAIKDLVYEMIIVSSNLATNIIIDLI-DA +KNVTQTMRDFGAKDIQILRGVEDSK-AFQQNLNNTVNAYDLKIIFEGIANGKVVDQKSCD +AMIKILLDQKF-NDIIPGKLPKNVRVAHKTGSISK-VQHDSGIVLLPDGRKYVLVLLSKD +WD-DEKSNKKMLAGISEMIY--- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TTU2014-066ASC TaxID=1729723 RepID=A0A0T6VPP4_9PSED +---FLAHIARVDDQTPGRLGVYVKDMETGIST-SYHGEEPWYLASTVKVPVAITVMRRIE +EGALSLDTGVPLLASDYVDGAGATNGFAPNTHSVRFLMEQMLIHSDNTASDMLIRLV-GL +ERVNTVTRELVPQGFGPITTLADVRRRYYATPYNSATLKAYGDLLSALDAGTALNPDSTR +YLLGVMRRAETGARRIKAGLPPTVGFAHKTGTQR-ARICDAGLVDQPEISRRLLIVACVR +EAASTAKAERALRGTGEAVT--- +>[subseq from] Beta-lactamase class A n=1 Tax=Fictibacillus sp. BK138 TaxID=2512121 RepID=A0A4Q7QRD7_9BACI +-kQIENDLLRLISSGKGTYGVSIYHFETEEEF-IHNQNEEFYAASIIKILIMSAVFAQVS +EGKRSLSDKIQVRSEDIVSGDGILKNLSPGMWTVHDLIVLMIIESDNTATNLLIDMV-GV +ENIQLYMTIWGFKQTQFRHKLQI-KPSRNHNDSNLITAKEMNHFLRNIAMGNIVSMSVCR +KMIDIMKQQKM-NDLLPRLLPEYWEMAHKTGYVP-GVEHNVGLFYIPGHT-FAISVLSKN +VP-NRDEPKRIMGDLGLMLF--- +>[subseq from] serine hydrolase n=1 Tax=Pseudoflavitalea rhizosphaerae TaxID=1884793 RepID=UPI000F8D2D5B +------------NHPEGYFAIAFKDLSTGKTF-FMNEHASFHAASTMKTPVLIETFRQAS +KGKFRIEDSIEIKNSSIVDGSPYSYTHIGQKLPVSDVLHRMITKSSNLATNIMIDLV-DA +KKVMVTMRKLGAKDMRVLRGVEDDK-AFEKGLNNTTTAYDLMLIMEHLEKGTAVNRRASE +AMIKILMDQHF-RDVIPAKLPAGTKVASKSGSIT-GICHDSGIVFLPDGKKYVIVLLSKG +IK-DHKVATNTLANASRIIYDHy +>[subseq from] Uncharacterized protein n=2 Tax=Cytophagales TaxID=768507 RepID=A0A1Z9SCY8_9BACT +---LENKISNLIKSHKGTFAVALKSLDDGNTI-LINENEIFHAASTMKTPVMIELFKKKH +NGEVSFEDSLQIKNESIVDGSKFXYKKLGKYISIRELVSAMITKSSNFSTNLLIDYI-NV +KNVNKTMRDMGAENINVLRGVGDLKA-FDKGLNNTTSAKDLLVIYEKLAMGSFINPSISN +EMVEILKNQVY-KDIIPKYLPDNIEVAHKTGWIS-GVRHDSGIVFLENGKKYVLILLSKN +LDD-DIEGAEFLAKISLEIFN-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. KC207 TaxID=2530377 RepID=A0A4R4R1L5_9ACTN +------ELAALERRFDARLGVYAVDTGTGRTL-AHRADERFAYASTFKALAAGALLAATS +--DAELDRIVRYERADLVPHSPVTEQHVAGGMTLRAVADAAVRYSDNTAANLMLAELGGP +AGFERVLRGIGDTVTDPARTETSLNEAAPPR----------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A534A5K0_9BACT +--TLRARLEARIAQAPAQVGLYYRSLARPDSI-LIGANLRLHAASTMKVPVMIQIFRDAD +AGLLELNDSLTVHTASLVQGAAFTYAVVGQNRSVRDLLELMITRSSNLATNILIERV-GA +SRAQASARSLGAWSIQVLRGVEDGA-AYRAGLNNTTTARDLGVLLGAIAAGRAASRAACD +SMLVILGRQEF-NEGIPAGVPSGTRVAHKTGWIGEVVYHDAGVVYPPHGGSYVLVVLTGG +IKED-SVAHNLVADVSRMVWE-- +>[subseq from] Serine hydrolase n=1 Tax=Echinicola strongylocentroti TaxID=1795355 RepID=A0A2Z4IET5_9BACT +--ELREAINTRLDKVEGDFAVAFRSMGAEPVTlLINEKETFHAASTMKTPVMIALYKQVA +AGNIALDDSVKIVNESIVDGSPYSYGKIGQYSTYRELNFQMIMMSSNLATNILIDKL-DA +KKVTEAMRSLGAKDIEVLRGVEDLK-AYEQGLSNTTTAYDLMLIMEAIAGGKAVSEEASL +AMFEVLKAQHF-NEIIPGQLPKNVTVAHKTGSIT-GVRHDSGIVELPDGRRYVLVLLSKN +LKVP-SEGIEAMADVSRMLYEY- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000B886BE3 +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPQDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas sp. TTU2014-066ASC TaxID=1729723 RepID=UPI000A86E714 +---FLAHIARVDDQTPGRLGVYVKDMETGIST-SYHGEEPWYLASTVKVPVAITVMRRIE +EGALSLDTGVPLLASDYVDGAGATNGFAPNTHSVRFLMEQMLIHSDNTASDMLIRLV-GL +ERVNTVTRELVPQGFGPITTLADVRRRYYATPYNSATLKAYGDLLSALDAGTALNPDSTR +YLLGVMRRAETGARRIKAGLPPTVGFAHKTGTQR-ARICDAGLVDQPEISRRLLIVACVR +EAASTAKAERALRGTGEAVT--- +>[subseq from] serine hydrolase n=1 Tax=Nocardia acidivorans TaxID=404580 RepID=UPI00082FD67B +--------------------------DPGTEV-AVDAHERVVTASVYKLPLFVAFCRGVE +AGRIDPTARITVTPSDCTPPTGIAALHDPVTMSWRDLATSMMTVSDNAAADVLLGEV-GL +GPVEDLLRDLGLHETRIVGGTADQFEAYDPTYASATTPEEMTRFLSALWTGALLTPAHTD +FVRAVMRNQVW-PHRIAAGFPRGVTVAGKTGTVGI-IRNEVAVVEFPHEHPVAVAVFTRA +ARADLPAVDAAIAEAARIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus oceanisediminis TaxID=665099 RepID=UPI0011AADC03 +--TAEIQIKKLIDQAGGDWGIMVEDVENDISW-GYRTVDSFPAESVIKIPIMIAVFSVVE +NKELKLCDPVKIRLDDQVGGSGALQYLTPGILSVYDLLVLMIVQSDNTATNVLIDLV-GI +EHIQRTLLETGMKDSSFQRKLMVYPA--QSDLQNTVSAADVTLMLRKLIEGQLVSRHACE +QMIQILKWQQF-RNGLPSKLPPKWELAHKTGWDTD-RQHDVGILFTGNRT-MIVSVLSDN +VS--SEAAWNVMGDIGKIIYDY- +>[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00115902F9 +------------------------------------------------------------ +-----------------------------------------------------LATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLSAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] serine hydrolase n=1 Tax=Sphingobacterium sp. DR205 TaxID=2713573 RepID=UPI0013E4F3B2 +-rKLEKQIKQLIQGFQGEVGIYVHNLKKHKEV-NIGADSIFPTASVVKIPILVGVFDKIE +KGQLQLDQELIYRESQKYGGSGLMQFFKDSSVDLKTLVALMLSYSDNVTSIWNQKLAGGG +MAINTLMADLQLQHTRVNSQTEGRKTDWEKYGWGQTTPKEMADLLTLIRQGKVISEKSSD +RMYRFLGNMFY-DERGLSQIPATVKAASKTGSLDD-VRNEVMLVNAPKGD-YVFSIFTKN +NEGKTNAAEVLTRKLSKLLWDYy +>[subseq from] Uncharacterized protein n=1 Tax=Thermoactinomyces vulgaris TaxID=2026 RepID=A0A0N0H902_THEVU +--RLIQNLEHWKSNAVGNWGVWIEDLTSGTTW-VWNETKSFYAASIIKVPIMVAVYKQAF +LGRLALTDEIILTAEDQVGGTGVLQHLSPGLLSVQDLTTLMIIQSDNTATNILIDLL-GT +ETIRETMDELGMRQSTFYNKLMIVPAAPAG--LNLITAADVAQCFRHIAQGKAVSQHASR +QMVEILKKQQL-RDCFPTGLPSQWELAHKTGMVTR-TLHDAGILYTKSRA-MVMVALSEE +CE--YEQAQQQMKQLARLVYE-- +>[subseq from] serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=UPI0006B46177 +------ELQNVIQTLPGRYAVFAKNLETHKIF-AYHEHDIFPSASVIKVPILIELYRRVE +EDHLSLDHLLLMRKEDQVGGSGVLKDLTPGTYSLRDLATLMITVSDNTATNLLIDYL-GV +EWVNSTIRRLGAQNTELIRKLQRVPAE--YDQINHTCAFDMALLMEKLATGTAISLAVSE +QMVNLLTRCQG-PVSITKEPAAAVIIAHKTGSLSE-ASHDVGIVYSPHI-NYVAAILSEG +AP--------------------- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI0009A262C5 +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGAMLEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDLPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6AC48_9BACT +--TLADELERLTAESKARAAVALHDLESGLRF-SLRGDRWFHAASTIKVAVLLAVFRAAD +EGRLRLDDSLHVRNRFISAGSPFRYQAIGRTAKISDLAQGMISASSNLATNLLLDFV-GV +EYARKVLQDAQVSGVELRRGVEDH-AAHERGINNEVTANGLLMLLSA-VRGDFLSNQSKE +QAIRILLEQRS-KSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EQEGRRETVAAISEVIYR-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. A202 TaxID=2572899 RepID=UPI00114F4B83 +-------------------GATVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVALDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLARYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus centrosporus TaxID=54910 RepID=UPI000F0A3CE1 +-eQLREKLTQLLDKAEGSWGVVVEDLDRGQRF-AHRPDEAFIAESVIKVPIMAAVYAAAA +QAAFQLDERIPMRAEDQVGGSGILFALSPGLLTIREWVTLMIIQSDNTATNVLIDLV-GR +QRIEQTMIELGMEKSKYSRKLMIYPVG--ITENNMITPGDVSRMLGSIATGGFLSHHACE +EMVSIMKRQQV-LNGLPSLLPPDWEIACKSGWDS-GRQHDVGVFFSQGR-RFSIVALSQD +VQ--SESALRVLGQIGKEVYEY- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V2RLP9_9BACT +--TLGEHVERLAAQSKARVAVALHDLKSGLRF-SLHGDRWFHAASTIKVAVLLAVLRAAD +EGRLRLDDSLHVRNRFISVGFPFHYNRIGRTAKISELAEGMISASSNLATNLLLDFL-GV +EYARKVLRDAQADGVELRRGVEDH-AAHERGLNNQVTANGLLRLLSAL-RGDFLSAKSKE +QAIRILLEQRF-DSMIPAGLPPHAVVAHKTGEIST-ACHDMGIVYLPEREPYLAVILTEF +DS-DRDGRRETVAAISEVIYR-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A3S7Q8H3_9BACT +------------------------------------------------------------ +-------------------------------------------YSDYTAMNKLIAHLGGP +DKVTAFARGIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRHLTLGSALGETQRA +QLVAWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAGHLAEGRAPLILV----- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Sediminibacterium sp. WSJ-3 TaxID=2698829 RepID=UPI0013795FEA +---VSAEIKRLFAGQRGVFAMAFRNSQTGETI-LINEQESFHAASTMKTPVMIELFRLDG +LKKIRLTDSVVVRNSSIVDSSGYSYTQIGTKKTIGDLLYQMIIKSSNLATNLLIELA-DA +RQVTQTMRQLGAEKTQVLRGVEDSK-AYRKGWNNTTTALDLMTIYDKMARAEIIDAKACD +EMIGILLDQQF-NEIIPAKLPKEVRVAHKTGSIT-GVQHDSGIVLLPDGRKYVLVLLSKN +LE-DEKAAVETLAAVSELVYRY- +>[subseq from] Serine hydrolase n=1 Tax=Luteimonas terrae TaxID=1530191 RepID=A0A4R5UF82_9GAMM +------------------------------------------------------------ +---------------------------------------------DNMAIVRLRNADAGE +ARLQALARELGVARTDLDATLEGVFDAYYRSDRNTATLPAFATLLDRLAAGELLSPDSTR +LMLDHMRGISTGDRRISAGLPPGTDFAQKTGTQLR-RACNVGVVDPEARDGATLVLACAE +DFDDIADAETAFQGLGRAL---- +>[subseq from] Serine hydrolase n=1 Tax=Caldilineaceae bacterium SB0661_bin_32 TaxID=2605255 RepID=A0A6B1DA36_9CHLR +--SLESDIRDITADSGAEMAVSALHLESGQRF-DVDAERVYPLCSVLKIPVLVEAFRQIE +EGLFTLDDRWQLTTAEKNLPSGILVFFDDGLPTVRDLLTLMIIISDNTATDMVMHRL-GE +GSVTRAMHDLGLTDIHVPLTIRELFDYSLGPDNDTGTPAALTELLARIWRGETVSRAACD +AMLDILLKQQL-NDRLPRYLPPGTPCAHKTGTLP-GIRNDSGIIYAGENAHVAVTAFSLW +DD--------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=A0A366F136_9BACI +----EVKILDAIDKCMGRVSVAI-DLP-SRSI-QINDDTPYPAASLIKVPILLEGFRQAE +QGGICLNETVMVPKEDRVGRAGVLSALSGNMLTVEDLLTLMIIVSDNTATNLLIDRI-GA +EAINNLCNSLALKHTKLSRKLMDFQSM-EQGYDNLTSASDIITCLRILDQSPLFSEQSRE +KMLSILHQQQF-DTKLPARIDERVFIANKTGELP-GVEHDCAIVRCNQK-TAYIAVLIDG +LEEN-ESARGTIAEIGKLLYDY- +>[subseq from] serine hydrolase n=1 Tax=Flavobacteriaceae bacterium S2-4-21 TaxID=2607998 RepID=UPI0011F00965 +------HIRTQIDAIDGEVAVAFQNLSDDDRL-LIHGDETFHAASTMKVPVMIELFKQQR +EGLIDLNDSILLVNESIVDGSPYQYSNIGQKMTFYDLLYPMITVSSNLATNVLIEWA-DA +KKVTATMRDLGAQNIEVLRGVEDIK-AYELGLSNTTTARDLMVIMQAIAEHKAGSPDDCK +EMLRILKDQRF-NEIIPFYLPDSVEVAHKTGSIT-GVHHDAGIVYLPDGRSYVLVLLSKN +LE-NFEEGTEQLAGISKTIYEY- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7PBP6_9BACT +--SLRDALSPLLAAHEGVATAAVRDLKTGVGF-SAGADRPMPLASLVKVPVMVAAYAAAH +EGRLSLDEQITFAADDVVPGSTVIDKLSPGAFTLRDAVRMMIASSDNTATNLVIRRI-GL +PATNVVMDRVGLSGIRLNRRETSLDVRSREFGLGNGTAAELVTLMGMLHQDGIVAEGACE +AMLGHLLACED-RGTAGRDMPAGVKVAHKTGLVS-GVRTDAGLILGPAG-PIAFCLLTKD +NRAPGGPADDLIAKVARAALD-- +>[subseq from] Serine hydrolase n=1 Tax=Aminipila sp. JN-18 TaxID=2507160 RepID=A0A410PU39_9FIRM +-----DEIIEKISKADGKVGFYYKNLVTGEEI-KFNENETFRPASVIKLPIFAEISRRDA +LKTADMAEKIVIKNSEKVPSCGALTLFTDEPVDIRTLCNLMIAISDNTATNVLIKRF-GI +EALNEGFRIMGLEKTRVNRLLFDMEAA-AQGKENVVVPQEIGRLLEKIYRKEFVNEEVSE +KIAETLLAQQV-NHKIPGRLPEEIGVAHKTGDDD-GITNDVGIVYAK--EPFVIVFLSNE +TD--VPAFEQIIRDVT------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium siyangense TaxID=459529 RepID=A0A420G4X2_9SPHI +-kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE +KGELQLDQQLLYRASQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG +VAINKLMSELQLTQTRVNSQTEGRKPDWERYGWGQTTPKEMADLVTLIRQGKVVSQKSSD +QMYRFMGNMFY-DERGLSQIPSTVKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN +NVGKTNEAEALTRKLSKLLWDYy +>[subseq from] Uncharacterized protein n=1 Tax=Cyanobacteria bacterium UBA11991 TaxID=2055789 RepID=A0A3D0SHL1_9CYAN +--SLKAELLSLMENYTIKPAIYVWDYESQNYV-DINASKIYPVASIIKIPVLIDLFKSIE +NKSVSLNEKIPLTEYYRSEGSGNLQFMAGNSWTVDNLARIMITNSDNSATNMLMSKIGAM +TEVNQSIRDWGLKNTEIQTWLPDMKGT------NHSTAREIAQMLYNIDTDEFLSDKSRN +KIYDYMSHVHN-DRLIQAGLRAGSTFYHKTGDIGT-MLGDAGIVVTPNGGRYIVVILATR +PHNS-VLGKEFIVKASQIIYNY- +>[subseq from] Beta-lactamase class A n=2 Tax=Candidatus Chrysopegis kryptomonas TaxID=1633643 RepID=A0A0P1NTU9_9BACT +-kQLISKIQDVAEKYGGRLGVSAKNFVTGETI-QINADSLFPTASVIKVPILVELFYRFN +EGKLKKDTLINLEDSLKYGGSGVLQYFYDGALKLIDVAVLMIILSDNTATNLVLDCFADL +DAVNNRMKSLGLNNTKILNKLMSFKTNTPESLRGYTTPNDMVKLLELLAGGKIISPETSA +EIINIMKNNQD-YEMMKRYLPEKVTVANKTGSIDR-MKADIGIVYSQCT-SYAVAIFCDQ +LSAVDNKGHLAVAEISKLIFDYf +>[subseq from] serine hydrolase n=1 Tax=Bacillus soli TaxID=220688 RepID=UPI0008260BCF +--KLETKLKEELLGCDGRLGLAIEI--GNEQF-LYQSEAVFQSASVIKVPILIEGLRQSD +QGKIKLDEVTAITN--KVGGSGVLQALSGHAMTIKDLMTLMITVSDNTATNMLIDLL-GM +ESINLTMEKLGLSNTVLNRKMMDFE-AIERGWDNFTSPIDMITCLKAVNEGSFLAKESKK +AALEMMNNQQF-LDKLPAMMDDKIFVANKTGGLP-GVEHDCAVIKYRGKT-AYIAVLMDK +LN-DVSAGTQTISRIGRRLYEY- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A6B1BGJ5_9BACT +-----------EHESPGTIGVSVIS-PQGERW-ASRGDHQFPAASTVKIPIMIEIYRAID +RGTLALDDTYIVRSVDKSPGSGVLRHHTGLQLSFGDLLYLMMSISDNTATNILIEVA-GM +DRINETMRELGMTASTLGRPMRGRL-AVEGEQENWATPNNYTAVVKTILDDQAASPASCQ +AMLTTLTQQQN-GRRIGRYVPKTYRWGSKTGSNR-GIINDVGFVESPAGT-MVIALYSLK +LG-DHVTGECALSEIAKVAMQ-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium acetobutylicum TaxID=1488 RepID=UPI0005431BC6 +---LKKTIENLITSNKEDISLVFLDLKNPSNHiYIKENKVFPSASTIKVLIMAEALNEVL +SGNHALEKKIEIKSSDKVNYSIITC-LTNKIYPLIDLLTLMIISSDNTAANILIDLL-TM +DSINKYGKKIGLKTTLLRRKMMDSNAA-KEGRENITTAFDMLTLFSKIYNKKILSPDMCN +LMLNILSNNTD-CEVLLRYLCDDIRCAHKTGDLPH-LNHDIGIFKTENA-EYILGVFVRN +AQFN-YEAKDIIGRISKEIH--- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI000FF32242 +--TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLTGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7EEY3_9BACT +--TLRHQIEKIEKESGATIAVALRDFESGLEL-HYHADRWFHAASTIKVPILLGVFAAID +RGELLPHSRVHVRNRFLSVNIPFRHNAIGKMMRVDELAYHMITTSSNLATNLLLGVM-GT +DAVNETLKELHDKGIELRRGVEDEL-AFEKRINNMVTADGLLRILVMLAEGKAFSPGLCR +RMMDILHGQEF-NQGIPARLPKVARVAHKTGEIST-VAHDAGVVYLPKRKPYVLVILTEW +DPA-VAGRSRTIAAISHTIYEY- +>[subseq from] Beta-lactamase class A n=1 Tax=Aneurinibacillus thermoaerophilus TaxID=143495 RepID=A0A1G7Y4A6_ANETH +-qKLRRDVERIVSQVDGKVSVAIE-TDEGHIL--INANDPLPSASLIKIPIMIAAYRQAQ +EGKLNLFSEYSFLPEDRVGGMGVLSHLSPELLTLKDLISLMIMISDNTATNMVIRNV-GM +DTVNQLAADLNCGQTVLVRMMMDH-EAVKRGKDNMTSASDIVRFLKEIVEGSILNEENKK +AVYDTLLNQQF-HTKLPAGFSLHATLAHKTGELP-GTEHDAGIFCFNGK-YAYVAVLTTE +LS-DNASGQRVIAQVGKLVFDY- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus saganii TaxID=2303992 RepID=A0A372LRU5_9BACI +---LENAILSEIDKCTGRVGLYLEM--EAGKI-EYNSEEAFRSASLIKVPILIEGYRQKE +TGRIHLNQPVTVQRRDKVGGSGVLQALSEKSMTLKDIMTLMIIVSDNTATNVMIDLL-GM +GPINHSIKELGLTKTVLERKMMDFQAA-EQGKDNLTCAADMVLCLKAIHNAEFVSEDNSK +EMLEIMEKQQF-LDKLPGMMDDKAVVAGKTGSLK-GIEHDCSVIRYHEK--VAYAAVLTD +GLQSKEDGRRTITNIGKHIFDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora rhizosphaerae TaxID=568872 RepID=A0A1C6SK00_9ACTN +------QLARVAAATNNRAGVAVRDLSSHQQI-AVNGAFRPKAASVIKLWILVELLRRVD +CRQLSLDRAVRVTRDDVVGGTGKLKSEAPQVVTTSRLAEYMIEYSDNTAANVLIDQLGGF +APVNALIDSMNQRETVLAHKLFDGAA--DRGGENYTSPDDVVSLLGAVWDARILTESSRD +LMIGFMRKQTR-NSKIPAALPPGTPLAHKTGDDID-ASHDVGYCLTPGA-ETAVAFLTAG +PSR---TGSETVRQLARTVHD-- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora orduensis TaxID=1420891 RepID=A0A5C4QUZ6_9ACTN +-------------------GATVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVSLDEGVLVTPADVVGGTGQLQFETPQVVTLHRLARYLIKYSDNIAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus vireti LMG 21834 TaxID=1131730 RepID=W1SCH9_9BACI +---LEEKLKGEITCFQGRIGIAVEI--ANKRI-SLNSMEVFPSASVIKVPILIEGLRQAE +TGKINLNELTTIDK--RVGGSGVLQALSAKVMTIKDLMTLMITVSDNTTTNLLIDLL-GM +DSINSTIEKLSMEHTKLSRKMMDFE-AIEQGYNNFTSPSDMIKCLKVINEGDFLSEESRK +LAVEIMHYQQF-HDKLTAMMDDLVFAASKTGGLPN-VEHDCAILKYGGKT--AYAVVLTD +QLDNHFAAKHLISKIGKHLYDH- +>[subseq from] Beta-lactamase family protein n=1 Tax=Micromonospora sp. A202 TaxID=2572899 RepID=A0A542EYW7_9ACTN +-------------------GATVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVALDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLARYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] serine hydrolase n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=UPI00130ECBE6 +------------AALSGKIGCYYKNLVTGETC-TWHGDIPVIAASVIKLYVMTEAFAQIE +AGKLAMDQEITVHRKDCVPSCGVLTYHDDVKLQVIDLITLMIIVSDNTATNVLIDLL-GI +DNINARIRALGFEKTILNRKLFDAEKA-KLGLHNYITAEEVGALLEMMYRGTLVSEAASA +RMISIMKDQQL-NHKIPYLIPQAPQIAHKTGEDDN-TTHDAAIIFS--REPFILCICSND +TDV--TKLEPAMGRIAKR----- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_1_40CM_3_65_5 TaxID=1803450 RepID=A0A1Q7N1J2_9BACT +-qRLQASIERTTRSISAAWGVYVKSLETGEEI-ALDADRQMETMSTIKIPLMVEAFEQIK +AGTFKLTDKYTFAQGDSQPGTGTIQRLDPGAMTVKDLLTMMIIVSDNTATEVLYRMVGGP +DAVTRRMDALGLTKTRAMNIPSKWFARDGKNPFGLSTPREMGRLLEMMERGTLVDKASSE +LMLQMMRGQLY-RTRIPRYVT-GYRIPHKTGDFLPYVGDDVGMLEAQGK-TIIVSIFTGN +HFGSGEALENAIGLVAKDVADYf +>[subseq from] serine hydrolase n=1 Tax=Paenibacillus elgii TaxID=189691 RepID=UPI000248CF35 +-nQLEATIREAASSVEGKVGIAV-DTAEGQIH--IYADEPFPSASLIKIPILLEAYRQAQ +EGRLDLHQPYAVPSGERVGGTGVIHQLSGTLLTLQDLMALMIIVSDNTATNMIIDLI-GM +ETVNKLSAGLGCGATVLGRKMLDFQAK-RNGKDNFTSARDMIIFLKEIVDGSTLKQEAKD +AALQLLRNQQF-NAKLPARMIDKPVLAHKTGELP-GTEHDAGILQVNGK-TAYIAVLTTD +LV-DNLPAQQVISTIGKAVFDY- +>[subseq from] Uncharacterized protein n=1 Tax=Eggerthellaceae bacterium TaxID=1972561 RepID=A0A3C1DEL3_9ACTN +---LESDMQAIVEASGVPVGAAVVDLPTATRA-DYQGNLSLPAASMIKLLIAHAFLEGSK +TDPAGLDDVYTLQSSDIVGGTGTLGGLGAGAVTYRELVSRMIDVSDNTAANVLIDAVGGM +EAVNADARKLGLVGTELNRYMMDTD-ALARGIDNYTSASDCAKLLEMIYKGSFVDLASSQ +LMLQALEQQQD-EGGISAGLGSNVLFAHKTGSLSN-ARHDGGIVEG--EHPYVIVVLCGG +DGFYLDGANAAMRNIASAV---- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9YPK4_9BACT +-qKMVTAIERVDRDLSGVMAVGVLDLTSGRQY-LLHGDEILPQASSIKIAVLAELYHQEQ +SGKQRLNDLYTVRGEDLVPDSDIMLGLTPGVLTNRDLATMMVAVSDNSATNALIERL-GM +ENVNATLRSLGLHDTLLRRKMMDIKAA-QQGRENVSTPREMMTLLAEIYRHKLFDKALTD +DFFKVLSGNA-KDSKFVPVIPEGVVIADKPGELE-AVRTDSGIIFTSNR-PFVLSVMTAY +LR-DEHEGDKAIGEVARAAFEYf +>[subseq from] zinc_ribbon_2 domain-containing protein n=1 Tax=Pediococcus acidilactici 7_4 TaxID=563194 RepID=D2EGV4_PEDAC +---VEGTIRDAFGDISGDTAVYVSPVDSDTEV-DFN-DQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNGN-HTKLPHDLPTEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] serine hydrolase n=1 Tax=Sphingobacterium sp. HMA12 TaxID=2050894 RepID=UPI000CEA4873 +-kKLETQIKQLIQGFQGEIGVYVHNLKKHKEV-NIGADNIFPTASVVKIPILVGVFDKIE +KGQLQLDQELIYRENQKYGGSGLMQFFKDSSVDLKTLVALMLSYSDNVTSIWNQKLAGGG +IAINTLMADLQLQHTRVNSQTEGRKADWEKYGWGQTTPKEMADLLTLIRQGKVISEKSSD +RMYRFLGNMFY-DERGLSQIPATVKAASKTGSLDD-VRNEVMLVNAPKGD-YVFSIFTKN +NQGKTNAAEVLTRKLSKLLWDYy +>[subseq from] Beta-lactamase CARB-6 n=1 Tax=Paludisphaera borealis TaxID=1387353 RepID=A0A1U7CMN5_9BACT +-kTLAQRIEPLVKAHKGKVAVAVKNLKTGESY-VYHADDVMPTASLIKFPVMIEAYRQAA +AGRINLDSTIKLHKADKVPGSGILTDHFSDGFALRDAVRLMIKFSDNTATNLVLDAI-GM +GATAETMVKLGCPDTKIHSKVYRRDTRSKLYGLGSTTAAQMIRLCEELKAGRLVDPKASA +AMYEHLATCDD-KDKFPRFLPEGAKIAFKTGSVD-ASRTAAGLIECPAG-SVALCVLTTD +NEDQDNAGNLICAKIAREVFDHf +>[subseq from] Beta-lactamase class A n=1 Tax=Pedobacter ruber TaxID=990371 RepID=A0A1G9XZ66_9SPHI +-qKTENDLKEIIGSSPSLTGLMAIDLTSGEII-GINSDIVFTQASAIKIPILMEVYKQAH +EKKFALSDIKPLVASNIVAGSGILNAMTDPVLSIRNYCMLMIGLSDNSATNTLIELV-GM +KNINSTMQSLGFPNTKVQRKMIDQPAS-LRNEENLSTPAEAARIMKLLHEGKFIDKTSSE +EILSILKKNPIENSKLAGGLPSNVKLAFKPGGMG-GVSTEWGIVYLSNS-PYAIAVMENY +KT--SATPSDIIAAISKRVFDYf +>[subseq from] serine hydrolase n=1 Tax=Emticicia sp. MM TaxID=1839755 RepID=UPI0009EEF11F +--------------SGIKVTMAVENMEGKSYF-KHRIDVKVPSASVIKVPILMSLMEKVQ +ANELSLSEEHSLTNAEKAGGEGIFMSAAEGEFTIRKIAEEMIRTSDNTATNILIRKI-GM +ETINQNLTKWGTTKTRLNRVMMDIEA-VKQGRENYVNALEINALLRMIYDRKVANPILCD +EMIGMLKNCED-TTTIPSQLPKDLAIAHKTGTLAY-VRGDAAIVFTT--QPFVISIFVEG +FDKE-ATAEKIIGDLAKICWE-- +>[subseq from] serine hydrolase n=1 Tax=Fictibacillus sp. FJAT-27399 TaxID=1729689 RepID=UPI000785F886 +-nELNNRVNDIISGQNGDYAYWIE-TEDG-HI-EYQADEVFPAASLIKIPILIEAFRQTE +AGQIDLASRISLKQEVRVGGAGVLQLFSDESVTVADILTLMITVSDNMAANIMIEKT-GM +ERINDLLAELGCSQTVLQRKLMDFEA-VKQGKNNYTSARDVILQLKEIDRGGRLKDKSSQ +TILHILQNQQF-RYKLPAYMDEKITIANKTGELD-GVEHDAGIFTFKRE-KLFAAVLTKN +LP-SEAEGRQALALIGKALND-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=A0A655EGI6_MYCTX +------------------------------------------------------------ +---------------------------------------------------------GGT +AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA +LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR +AGYDAEPREALLAEAATCVA--- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SYI8_9BACT +------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTHKVFTAAELLRQKN +--TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV +ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKEK +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A353B773_9PLAN +------QLESLCEAHDGDVSVAVQIFGSCGRF-ERAAERTQPTASLIKLPVMMEYYRQVD +AGQLSPTQRIELTEADKVPGSGILTEHFSAGLPLEDIVRLMIRYSDNTATNMVLDAI-GL +ESTAATMKALGWPETQIHSQVYRRSTRSQKYGLGSTTASDMLEILVALHLGDLTSAESRQ +KMLAHLSSCED-DTKLGRYLPTGATLANKTGAVSR-VRTDAGIIRYRDHT-ILAVVLTSN +NATDRNAAERLCGRIGQVL---- +>[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A6D2GJR6_STAAU +---HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLN-------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus fluminis TaxID=511487 RepID=A0A3M8DNS2_9BACL +-dQLKETIIDLTAKAGGTWGVFVEDLDTGKSL-AHNEGELFLAESVIKVPIMAAVFAAAE +EKRFNLSDTMTLRREDMVGGSGFLQHMTPGILPIYDLITLMIVQSDNMATNMLVDLV-GA +DAINQTMRETGMKESHFFNKCCVYPV--KREGLNEITAADVNALLKTLATGSYISYHACQ +QMIEIMKKQQV-RNGLPAYLPESWEMAHKPGWDT-GRQHDAGILFAGKR-SVSITVLSKD +IEP--FSALDTLAKIGRSVYAY- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI001183428D +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLK-------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Clostridium tetanomorphum TaxID=1553 RepID=A0A037Z5V9_CLOTT +--KMIDKIKEEIDKFKGVCGVVIKNENTKEYY-AYNEEIVFPSASIIKLSILLELFKRIE +KGEFNLEDSVTIREEDKTGGFGVLKELDCNVLTIKDIATLMIILSDNVATNKLINIL-NM +ESINSTAKELGMKSTILGRKMMDGDA-KKRGLDNYTSPKDTLTILEAYLNPSKLSPENRE +TILDILKKQQC-NNKLPFLMPKNVSFAHKTGDLP-GVEHDAGILFSQAGT-IVIVVLTKD +LE-DNAHGVQFNNSIGKIVTKY- +>[subseq from] Uncharacterized protein n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=A0A1A3L0Q7_MYCGO +----ERQVERRILAAPADVAVLFRLLGGEAEW-SYQPDVTFHAASTMKVPVMIELFHQAH +QGQLTLDDPLLIHNESLVDGSAFYYSSEGQTRTLRQLCELMITISSNLATNLLIKKL-GI +ENIRATVHLLGADGMNVLRGVED-NKAYDLGLNNTTTARALAILLTAIAEGKVVDPDASR +QMVEILKRQHI-NDGIPSGLDPTIPVAHKTGTLK-AIHHDAAIVYG--SQPFVLVILVRG +MAN-SKDSSALMADITRAFYR-- +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus pakistanensis TaxID=759811 RepID=A0A5Q2NCB0_9BACI +------AIQRMLEEAPYNVHLFIKDPNTNHYFiQEKLHAVFSSASLIKVPILLGVLRYLE +RYHQDVHQEIRIAPEEWVDYSVISEQRIER-STIYELLVWMIITSDNAATNVLIDFI-GM +EFLNHYFRQIGLRQTKLQRKMMDFEK-LERGIDNLTSANDMAHLFSRIYQQDLLPKQFSK +LTIDILSRQRV-HESLKRYLVDDVKMAHKTGGLET-VEHDVGIVYNGSN-DYLIGVFITE +VT-NNEYAKQLIGRISKSAYEH- +>[subseq from] serine hydrolase n=1 Tax=Bacillales TaxID=1385 RepID=UPI000491383A +------SIGKLMEETGGQWGIYLEDVRTGERL-GFAEHQRFYAASLIKVPIMTAVFAEAY +AGRLALSDKLRLRREDQVGGDGVLQHLTPGTLTVYDAVTLMIIQSDNTATNMLIDLV-GT +DAIRAAMSRTEMVNSSFYNKLMIVPAEPEG--YNEVTAADMGSHFRCLATGKAISYNSCL +HMINILKRQQH-RDRIPCRLPPKWELANKTGTVTN-ITHDAGILYVGGHA-VTICTL--S +RDVDAKAAGEMMGRIGRMVYDLy +>[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas sp. SGT-18 TaxID=2493087 RepID=UPI000F62A000 +--ALEPRLRAIEAALGAGIGVYVLHMDRDESY-GYRAGEPWYLASGVKVPVAIAVLREVE +RGTLALDTPVVLRADDYVDGAGATNRHRPGELALSWLLEQMIVHSDNTATDVLIRTV-GL +AAVNRVAAELVDARLRIT------------------------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas sp. SGT-18 TaxID=2493087 RepID=UPI000F62A000 +------------------------------------------------------------ +---------------------------------------------------------AGP +ARVRKLAALLGVPPEQLRQDLAAAFEAYYATGANSATLVDYGRMLATLADGKALGAEATG +WLLERMLRVETGHRRLRAGLPPGIAFAHKTGTQYR-RTCDLGIAMQPDPARVVVAACVRG +TG--TAAGEHALQRIAAAIT--- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Cyanobacteria bacterium J069 TaxID=2420337 RepID=A0A3M1PQA1_9CYAN +---LTTTLQSLVAQSGLVSGVFVVDLDTGDYV-DLNGSLAFPAASTIKTPILVAFLQDVD +RQRVRLDESLTLQAGDLTGGSGEIQMELGSQFSALDIATKMITISDNTATNMVIHKLGGL +AALNGRFRDWGMSHTVLNNLLADLEGT------NTTSARDLSLLLTAVSQGDLLSLRSRD +RLIDIMRSTVN-NNLLAATLGPDAKIAHKTGNIDS------------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7ZP28_9BACT +-qRLQASIERTTKSINATWGIYVKSLETSEEI-ALDADRQMETMSTIKIPLMVEAFEQMK +AGKFRLTDKYTFAQADSQPGTGIIQRLDPGALTVKDLITLMVIVSDNTATEVLYRMVGGI +DAVNRRMDAMGLKSTRAMSLPTTWFAREGKHPFGLSTPREMGRLLEMMERGTLVDKASSD +LMLQIMRGQLY-RTRIPRYVT-GYRVPHKTGDFLPFVGDDVGMLEADGR-TIVVSIFTGN +HFGSGEALENAIGLVAKEVADYy +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus timonensis TaxID=2086577 RepID=UPI000D0F2F77 +----------------------VKETRNNTLLiCERFNEEFSSASLIKVPILMAVLHFVE +QNHRLLQESIRVNDENKVDFSIITEQNLRV-STLYELLVWMIISSDNTATNVLIDYI-GM +NELNNYFQLMGLTQTRLQRKMMDVKQM-EQGVDNMTSARDMEHLFSRIYRQDLLSTKYSE +LAINILCRQRI-QDCLKRYIEDDVRVAHKTGSLDT-VIHDVGIVFNDVS-DYLIGIFITE +VK-DTDNAKQLIGRISKEVYHH- +>[subseq from] serine hydrolase n=1 Tax=Actinomadura rayongensis TaxID=1429076 RepID=UPI0013527251 +-------VEDAFRAAGVTGWLHAEDVDTGRRV-GVRADEPVVLASVFKVPLLVAFFRRAA +AGLLDPAERVTLRPGDRAEGPTGTSILLDDVLSLRDLAALMITVSDNAAADVLYDRVGGA +DAVNADLAALGLTATRITGNGRELFAALNPVLTSRSTPREMAALLGLVWRDEAAPPAACA +QMRRMFGLQVW-PHRLSAGFPDDVRVGGKTGTLPT-IRNEIGVVEYPDGGRYAVAVFTRA +ARAALPQADAVIGAAARLAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. IC_126 TaxID=2547400 RepID=A0A4R0PT24_9PSED +------------------------------------------------------------ +------------------------------------------------------------ +----AVANALSLSESELKASMEQAYERYYARNLNSSTLEAYGTLLEKLVEGDLLSESSRD +LLFKDMKLDRYDAYRLEAGLPSDVPFIQKTGTQLE-RACHVGVIEPEKQEKTVIIVACAE +ALDEAKEAGAAFERVGEAIT--- +>[subseq from] Serine hydrolase n=1 Tax=Burkholderiaceae bacterium TaxID=2030806 RepID=A0A5C7PV72_9BURK +---------RIGEDAASAVAVAVYDFEHHTTW-SINPARWFHAASTIKVPVLLGVYDAIE +QHRFDPISRVHVRNRSVVDGRPYRQAAIGRMLTVHELAEHMIVTSSNLATNLLLDLV-GI +EAARASLARLHVSGIDLRRGVED-ESAWEAGINNRVTAAGLCETLRLVEEGKAISADASK +AMLDILHQQRF-RSGIPAGLPEDARVAHKTGEIST-VAHDAGIVYLDGRDAYVVVILTEW +AP-DVNARQETIARISRAVYEY- +>[subseq from] serine hydrolase n=1 Tax=Nonomuraea sp. 160415 TaxID=2495887 RepID=UPI00110C4F75 +-------FETLFRVAGVTGWLYAADIDSGREV-GHGADEPLPTASMFKVPLLVEFCRQAD +AGLLDPTSRVTVTAGDRVTPTGISAMLDDVTISLRDLAYLMIAVSDNSSADMLLGRV-GI +DAVNAMLAKYGLDSTRVTQSCRELNDSLDPARANRSTPREMARLFGLIWRDEAASRASCA +WMRAVLNMQVW-PHRLASGFPDDVAVSGKTGTLPT-LRTESGVVEYPDGRRYAVAVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] serine hydrolase n=1 Tax=Gemmobacter nectariphilus TaxID=220343 RepID=UPI00040C68AE +-------------AGGARIGLALS-LDGKMLF-AHRADERFISASVVKIAIMAEVFRAAD +AGVLRLDQPVTVTADMMAPGSGIMNHLAPGYLQLRDVLYLMMSISDNTATNILIDMA-GM +DRINATMQALGMSGSVLGRKMRGR-RAIAGEAENIAVPADYDRLIGAIVNGTAASAPACA +EMMDLLRGQQN-ERRLARFLPKGADWGSKTGTVE-GVVNDAGFLRTAKGT-AVLSMFTEG +FE-RMVDAEAVLGDLAQAAF--- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus sp. LEMMJ03 TaxID=2595056 RepID=A0A553KNI9_9BACL +------SIGKLMEETGGQWGIYLEDVRTGERL-GFAEHQRFYAASLIKVPIMTAVFAEAY +AGRLALSDKLRLRREDQVGGDGVLQHLTPGTLTVYDAVTLMIIQSDNTATNMLIDLV-GT +DAIRAAMSRTEMVNSSFYNKLMIVPAEPEG--YNEVTAADMGSHFRCLATGKAISYNSCL +HMINILKRQQH-RDRIPCRLPPKWELANKTGTVTN-ITHDAGILYVGGHA-VTICTL--S +RDVDAKAAGEMMGRIGRMVYDLy +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. PA15(2017) TaxID=1932111 RepID=A0A1Q9Y500_9PSED +------------------------------------------------------------ +----------------------------------------------------------GP +QRVEAVANALKMKPDQLERDLDEAYQRYYETGLNSATLVAYGQLFGKLANGELLSEASTR +LLYDIMGLDSYEAYRLEAGLSEQVPFVQKTGTQQH-RACHMGIANPQGEDALVILACAEA +LDED-AEAGKLFEEVGEAIQ--- +>[subseq from] serine hydrolase n=1 Tax=Arenibacter latericius TaxID=86104 RepID=UPI00041DF09C +-eNLKQTIQAQIDSIDGTVAIAFYNLSAPKDSlYINVDEKFHAASTMKVPVMIELFKQAN +EGKINLNDSIILKNESIVDGSLYSYQQIDTKVALKDLMYSMITISSNLATNVLIELV-DA +KKVTASMRDLGAEKIEVLRGVEDLK-AYEKGLSNSTTARDLMSIMKSIANYSAGNKKDCE +AMIAILKDQQH-KEVIPFYLPKEVKVAHKIGSIT-GVHHDAGIVYLPDGRAYVLVLLSKN +LK-DFDKGTDQLARISKTLYNY- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. ALFpr18c TaxID=1458665 RepID=UPI00124AF5DC +-------------------GATVRDLSGDQQI-AVNGALRPKAASVIKLWILVELLRRVD +CGQVSLDEGVLVTPADVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNIAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia sienata TaxID=248552 RepID=UPI0007A50B66 +----AERIRAVFADAGCTGRLHARRCDSAAEV-SIGGAERVVTASVYKLPLLLAYCRAVD +AGRLDPLARLTLTPSECTPPTGISALHDPVTMSRRDLATSMMTVSDNAAADLLLGEI-GL +AAIHELLESLGLEQTRLVGGTADIQRAYDPAYTSATTPEEMTRLLAALWRGEVLSGEQTD +FARAVMRRQVW-PHRIAAGFPRGVAVAGKTGTIGI-IRNEVAVVEFPGEHPVAVAVFTRA +ARADLPAVDAAIAEAARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Psychrobacillus psychrotolerans TaxID=126156 RepID=A0A1I6ACJ5_9BACI +-eELVSEVQKLVEQSKGTWGIVLEDLNSGEKW-FHNEQELFYAASVIKVPIMASVYRAVD +RGDLSLMDLIILNEKEYVGGSGVLQHFTPGLLPLQDVIMLMIIQSDNTATNLLIDLV-GV +DDIQNSMKEAGMVYSTFYNKLMLSKSNPKG--ANRIAAADIAILLHKMAMGDLVSGKASR +QMVEVMKKQQV-RDCLPERLPSPWELANKTGWIP-GTRHDAGIFYVGNRK-LIATVLSKD +ED--DLLSKRILAQIGEEIYKY- +>[subseq from] Serine hydrolase n=1 Tax=Ilyomonas limi TaxID=2575867 RepID=A0A4U3L5F7_9BACT +-kKLRANIQSLLQGFNGDVGVYVHDLEKGKTV-AINADSIFPTASMIKIPILIGTMHKIE +DSELQYHQELIYSDSLLYPGVDILGSFKDTEIELSKIMMLMLTMSDNTASLWLQSLAGGG +QRINAYLDSLGMKVTRVNSRTPGRKDNQSKYGWGQTSPREMATLMEMIVKGQIISKAASD +RMLRLLSRNYW-DEEAVSQVPAGVFVASKNGAVDE-SRSEVMYVNGKHC-RYIFCICTNN +NKAANNEAWVLTRKLSKLLWEYy +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus oceanisediminis TaxID=665099 RepID=A0A562JIK2_9BACI +--KLKAEILELANCCEGRVGVYIQS--EEGII-EENCRKAFSSASLIKVPILLAGLSQAE +TGLLQLEEEVQINNAVRVGGSGVLQSMSKGLMKVIDLMTLMIIVSDNTATNLVIDLI-GK +ENINGYMKNIGLKNTELNRKMMDFE-ALKKGVDNTTTARDMAFCLEGLAERSILSVENKD +LARRILNGQQYKNKLANTVDLEKVQVANKTGELP-GVEHDCGIFTGNGR-TVYTAVLVDQ +LKN-QAAGRDVLSFIGNRIYR-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. B29 TaxID=1933220 RepID=A0A1P8EAL9_9SPHI +-kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE +KGELQLDQQLLYRASQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG +VAINKLMSDLQLAHTRVNSQTEGRKPDWERYGWGQTTPKEMADLVTRIRQGKVVSQKSSD +QMYRFMGNMFY-DERGLSQIPSTVKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN +NTGKTNEAEVLTRKLSKLLWDYy +>[subseq from] serine hydrolase n=1 Tax=Halomonas socia TaxID=1081866 RepID=UPI0013D0AE94 +------------------------------------------------------------ +------------------------------------------------------------ +---AAFAERLGVAPGELAVDYDAAFDAYEDSALNGGSLVAFGDLLATLARGDGLSAASRE +ALLAVMQRTRSGEARLKAGFGDDVVFAHKTGTQHR-RSCDAGIAQRGSGRQVAVVACTRG +PLA-VAIHERLLAEVGAAI---- +>[subseq from] serine hydrolase n=1 Tax=Litoribacter sp. XAAS-A1 TaxID=2598460 RepID=UPI00117D5D8B +--TLKAEITEELSSVEGDFAVAFRLLGSNKEI-LINEKENFHAASTMKTPVMIEVYKQAA +AGIFQLSDSITVHNESIVDGSAYSYDRIDKKATIYDITYAMIIKSSNLATNILIDLV-GA +EETTGSMRDIGAPDIMVCRGVEDQK-AFDQGLNNTTTAYDLMVIMEAIATGNAVDEEADA +QMFDILADQYF-KDLIPAHLPEDVVVAHKTGFIT-GVQHDSGIIRLPDGRQYALVLLSKN +LG-DRDEGKRVMANVSKMIYDY- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. S3 TaxID=486398 RepID=A0A513RE21_9BACI +--RLMEKIEEELRGLSGRAGLAIEM--EGKCI-DINSKEVFQSASLIKVPILIEGLRQSD +RGTLNVNQLVSITS--PVGGSGVLQVLSRDALTLMDLMTLMITVSDNTATNILIDEL-GM +EAINRSMVKMGLQHTVLNRKMMDFQ-ALEQGRDNYTSPADMLTCLKVIMEGSYLTEESQA +AALRMMKFQQF-QDRLPGMMDDRVMAANKTGSLPH-VVHDCAIITYKGKT-AYAAVLLDR +LD-DEFTGNQIISRIGKHIYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8CEH4_9BACT +-qRLQASIERTTKSINATWGIYVKSLETSEEI-ALDADRQMETMSTIKIPLMVEAFEQMK +AGKFRLTDKYTFAQADSQPGTGIIQRLDPGALTVKDLITLMVIVSDNTATEVLYRMVGGI +DAVNRRMDAMGLKSTRAMSLPTAWFAREGKHPFGLSTPREMGRLLEMMERGTLVDKASSD +LMLQIMRGQLY-RTRIPRYVT-GYRVPHKTGDFLPFVGDDVGMLEADGR-TIVVSIFTGN +HFGSGEALENAIGLVAKEVADYy +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9C597_9BACT +----------------------------------------------------MELLRQAQ +AGRLKLDDRVAIKQVQMVGGSGVLQFFGDASISLRDLAVLMIVLSDNTATNILIDQV-GM +ANVNDTLAHLGLAQTRLQRRMIDTAAQ-RAGRENLSTPREMTTLLELLHGGKVLDASHTA +ALLEILKYPKENASPLRNGLPDGIALANKGGSLP-GVRCDSGIVLLPDR-PYVISVMTTY +GH-DSHAAERAISEVSRRVFEYf +>[subseq from] serine hydrolase n=1 Tax=Steroidobacter cummioxidans TaxID=1803913 RepID=UPI000E316757 +---LSRLLEAELSRLPTRSGIYVKHLSTGETA-SVRGTDEFESASTIKLATMVLAYRLAD +ERKLDLNQRYVIKQADYRGGSGIFRHHDPGMPTLRDLITQMVITSDNTATDIMIAKVGGK +EAVNRFLRDAGYQVLRQNNTTLEFFRAVWNDKANWATPQEMGRLLESIELGTAASEQSCE +EMKRILLAQQSGVIKLPHYLT--VPIAHKTGETGT-VTNDVGMIYARSGT-IIISFYNVE +LSGPRAETEDGMGRVARTVVDYf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. TaxID=341027 RepID=A0A3C0ZFD9_9SPHI +-kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE +KGELQLDQQLLYRASQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG +IAINQLMSSLQLPHTRVNSQTEGRKPDWEKYGWGQTTPKEMADLVTLIRQGKVVSSKSSD +QMYRFMGNMFY-DERGLSQIPSTIKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN +NTGKTNEAEALTRKLSKLLWDYy +>[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax wautersii TaxID=1177982 RepID=A0A1I2FBM6_9BURK +-----------------AFGVYVRDLDTGDAL-SFHGAERWYLASSVKVPVAIAVLRGVE +RGAFTLDTPLTLREADYVDGAGPTKRQAAGTLTVRWLLEQMIVFSDNTASDMLIELV-GL +PAVNAVAQEAAPGGLERITTLADVRRAYYATGLNSGRLDAYGELLAQLAQGRLLNPAHTR +YLLGVMERVQTGPQRIKAGLPAGVTFAHKTGTQR-ARTCDSGLITRPADAVRAIVVACTR +GEPSTTRSDRTLRQVGIAICQ-- +>[subseq from] Serine hydrolase n=1 Tax=Terrabacteria group bacterium ANGP1 TaxID=2569760 RepID=A0A537KGT8_9BACT +-------------PVGAAVGLYYRSLAGSDSL-LVNAHARFHAASTMKVPVMIQLFRDAD +AGRLSLADSLRVHADSLVDGSTFLYESIGRRVSVRHLLELMETVSSNLATDVLVERV-DA +KRANATAHALGADSIVVLRGVEDGK-AYRAGLNNTTTARDLGVLLTAIAQHRAASPASCD +SMLAILGRQHF-TEGIPAGLPAGARVYHKTGWIEGVVYHDAAIVEPPDGKRYVLVVTTGA +IKPD-SAAYRLVADLSRLVYD-- +>[subseq from] serine hydrolase n=1 Tax=Psychrobacillus psychrotolerans TaxID=126156 RepID=UPI000B876727 +--ELVSEVQKLVEQSKGTWGIVLEDLNSGEKW-FHNEQELFYAASVIKVPIMASVYRAVD +RGDLSLMDLIILNEKEYVGGSGVLQHFTPGLLPLQDVIMLMIIQSDNTATNLLIDLV-GV +DDIQNSMKEAGMVYSTFYNKLMLSKSNPKG--ANRIAAADIAILLHKMAMGDLVSGKASR +QMVEVMKKQQV-RDCLPERLPSPWELANKTGWIP-GTRHDAGIFYVGNRK-LIATVLSKD +ED--DLLSKRILAQIGEEIYKY- +>[subseq from] Beta-lactamase regulatory protein BlaB n=2 Tax=Planctomyces sp. SH-PL62 TaxID=1636152 RepID=A0A142YJ03_9PLAN +--DLAGRIEMLTKAHKGKAAVALKNLRTGESY-ALNADAPMPTASLIKFPVMIEAYRQAA +AGKIDLAAPVTLTKKDKVPGSGILTDHFSDGFPLLDAVHLMITFSDNTATNLVLDAV-GI +GSTAATMEAMGFPNTKIHSKVYRRDTRSKVYGLGSTTAADMIRLFEALHARKLVDEKASE +AMWNHLLTCDD-KAKFPRFLPPGTKLAFKTGSVDE-SRTCAGVIETRGG-PVALCVLTTD +NETDDNAGNLLCARIAREVYDHf +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas sp. PA15(2017) TaxID=1932111 RepID=UPI0009F85C3D +------------------------------------------------------------ +----------------------------------------------------------GP +QRVEAVANALKMKPDQLERDLDEAYQRYYETGLNSATLVAYGQLFGKLANGELLSEASTR +LLYDIMGLDSYEAYRLEAGLSEQVPFVQKTGTQQH-RACHMGIANPQGEDALVILACAEA +LDED-AEAGKLFEEVGEAIQ--- +>[subseq from] serine hydrolase n=1 Tax=Ornithinibacillus sp. L9 TaxID=2678566 RepID=UPI0012D8A7AF +-eQLAEKISQKIEQVGGTWGIALEDLDTGEVW-LRNSDETFYAASIIKVPIMIAVFHAHE +YEGLSLSETIKLRSEDIVGGCGVLQHLTPGILSLHDLTTLMIIQSDNTATNMLIDVL-GK +EQIQQVMKDYGLNKSEFHHKLMTVPV--EKEGSNCITAFEMTSLLKKIVTGKVVSFHACE +KMIEVLMRQQI-TNGLPAKLPKSWMFAHKTGNVHQ-TRHEIGIFYIGKRK-MIVSVLAKG +ID--DRILQEAFTEIG------- +>[subseq from] Serine hydrolase n=1 Tax=Thalassobius sp. TaxID=1979401 RepID=A0A2E9G4R8_9RHOB +----------------------------QDSI-LINATEEFHAASTMKTPVMFEVFKQVE +AGKLDLSDSILIKNNSIVDSSEFVYQVIGDSLPLYDVMYKMIIKSSNLGTNLIIEKV-GA +KNVTQTMRDLGAPYIQVLRGVEDLKA-FEKGMSNTTTAYDMMVLYEKIANSEVLSKESNE +KMIEILLDQYY-NEMIPAKLPTDVKVAHKTGSIT-GVRHDAGIVMLPDGKKYVLVLLSKN +LENP-DASIEKMAEVSGKIYQY- +>[subseq from] serine hydrolase n=1 Tax=Laceyella tengchongensis TaxID=574699 RepID=UPI0012B906B1 +---LIQNLEHWKGRAVGNWGVWIEDLTSATTW-AWNETKSFYAASIIKVPIMVAVYKQAF +LGRLALADEIILTAEDQVGGTGVLQHLSPGLLSVQDLTTLMIIQSDNTATNILIDLL-GT +ETIRETMDELGMRQSTFHNKLMIVPAAPAG--LNMITAADVARCFRHIAQGKVVSQHASR +QMVEILKKQQL-RDCFPTGLPSQWELAHKTGMVTR-TLHDAGILFTKSRA-VVMVALSEE +CE--YEQAQQQMKQLARLVYE-- +>[subseq from] Serine hydrolase n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A2W4Q9B6_9FIRM +----LAEIEEIARGFSGRLGVWACRVDGGEPV-AYGAEEPFPTASTIKVPILYEVFRQAG +EGRFRLEDPLPLTRENQVPGSGVLKDLTPGILPVRDYCTLMITVSDNTATNVLLDLV-GV +EAVTRSMAAIGLHRTRLYRKIFQGS-----GPLAESTPADLGRLLLGLARGEWLTPGACA +EMLGMLYRQQH-KEMLTRYIDDYVRVASKSGWSDD-VRADVGLIETPSV-RYVVAIMSKG +CRPPDPGGAIVLALLSRALYDHf +>[subseq from] Beta-lactamase n=2 Tax=Candidatus Sulfopaludibacter sp. SbA4 TaxID=2043165 RepID=A0A2U3LIV9_9BACT +--PLQQAVRARIGDFQGMVSLYAKNLDTGAAF-GIRESEPVRTASTIKVPIMLAVFDAVS +RGQAKWSEPLTVTAAEQVSGTGVLGEMSDGDLPLRDVVQLMIVLSDNTATNLVLERF-TA +DAVNAYLDKLGIRTTRVMRKIRGDGSENEKYGIGMSTPRDMATILEKLERGEIVSRDASR +EMIAILKRCQD-GTGIRRRMG-GLAVANKTGSLD-ALRSDVGIVYSKGG-RIAMAITVDG +MPTPDNTGSVLIADLAKILVD-- +>[subseq from] Beta-lactamase n=2 Tax=Cyclobacterium marinum TaxID=104 RepID=G0J738_CYCMS +--SAQQSLKAYLKTIDNKVSLYIIQNKQGKILsMSNSDKIIPSASIIKVPLLIYFMQKAS +EGTFSLQDHYHLKDEDKVGGSGELQFKPAGIVTYEYLAKEMIRVSDNTATNIIIKKL-GL +KAFQKWMKENDYSATQLNRFMMDFD-AIEKGKQNYCSSKEINRLLLALYNGDLLAENPSL +KVIEWLKNCED-NTGLPHLLPDRVAIAHKTGTLDY-VRGDAGIIFGE--NPIFITVLVEN +FS-EIAEADSIISTIGRLAYLEy +>[subseq from] Serine hydrolase n=1 Tax=Microbispora bryophytorum TaxID=1460882 RepID=A0A544XUK8_9ACTN +--------ERVFRSAGVTGWLHAVDIDGGREV-GLRADEPVVLASVFKVPLLLELHRQAE +RGLLDLTERVGVPAADRTGGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLARV-GR +EAVNTLLDGLGLTATRVVQDCREMLTALDPAWGNRSTPREMTRLLAAIWRDEAAGPASCA +AIRRLMALQVW-PHRLASGFPDEVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +LSQNQPRADAAIGAAARMAIDQ- +>[subseq from] Serine hydrolase n=1 Tax=Opitutae bacterium TaxID=2026771 RepID=A0A2G4HJJ2_9BACT +---LEAQLRALIVSFKGTVTLHARHLESGAEV-GIEPDKPVRTASTIKLPIACAVAAQVA +AGQARWDERLTVADASKVSGSGVLSEFSAGEISLRDAVRLMIVVSDNTATNLVLDRI-GA +DAVNDYMDSLGLRRTRALRKIRGDGTDNQRFGTGSSTPREMTRLLGMLADGKVVDEAASR +DLLDTLKRQQY-KDGIGRQSG-SLHVASKSGSLD-ALRSDVGIVWTPQGR-IAVAITVDD +MPSPDNAGNLLISRLSQ------ +>[subseq from] serine hydrolase n=1 Tax=Cyclobacterium jeungdonense TaxID=708087 RepID=UPI0013D17C02 +----------------------LIQDETGKLLaQRQPNKKVPSASIIKIPILLTLLEAVD +KGELALDSVHVLKSQDKVGGAGELQFVPDGTLTFRFLAREMIRISDNSATNILIEQL-GM +NRIQDWLSIRGFTDTQLNRKMMDFD-AIERGHQNYTSPTEINRILLMLVQKDKLPANSIA +EALVILKSCED-NETLTAFLPTKLEVAHKTGTLDY-VRGDAGIIF--GRRPLILSVFVEN +FD-DISEAEKIIAEIGKLAYETy +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TTU2014-066ASC TaxID=1729723 RepID=A0A0T6VPK7_9PSED +--GLEEELRRIDDEAPGDLGVYIKHLGDDAQL-RYNAERFWYLGSAVKVPIAVALLQGID +DGEHSLDERLSLQADDKVDGSGDLVWQDEGVYSLRDLLTEMLIESDNTAANMLIRLV-GE +DELNQRTRKMGGDGFERITTFTQVRRRYYARKLNSSTLVAYGALLERLVRGELLSEASRD +VLYADMKIDSYDNYRLEAGLPEDVPFIHKTGTQLE-RACHVGVIEPRDEARAIVVAACAE +GLDEGKEAGQLFERVGQAIT--- +>[subseq from] Uncharacterized protein n=2 Tax=Hungatella hathewayi TaxID=154046 RepID=D3A9C2_9CLOT +----ELNVADQIKALPGKTGFYYENLVTGERA-AYHEEERMMAASVIKLFVMTEAFTRFE +EGTLSPDRIIRMRREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTATNVLIDLL-GI +EEINRTIRRLGYRDTVLRRKMYDTEKS-KQGIQNYITAAETGRLLREMYQGRLVSRTASE +AMISILKNQQL-CSKIPQALPEEPEIAHKTGEDC-GITHDVGIIYAKQ--P-FIVCYCGN +DT-DTPAYERVMAETALWLY--- +>[subseq from] serine hydrolase n=1 Tax=Fulvivirga lutimaris TaxID=1819566 RepID=UPI0012BD00FA +-eQLERTVMAQIDSIDGTVAVAFYSLTEPKDSlYINIGEKFHAASTMKVPVIIELFKQAA +EGKLDLNDSILLKNESIVDGSLYSYQQINTKVALKDLMYSMITVSSNLATNVLIELV-DA +KKVTATMRDLGAKDIEVLRGVEDIK-AYDQGLSNSTTARDLMVILESIANNRAGSQKDCE +VMITILKDQQF-NDIIPKYLPKEVTVAHKTGSIT-GVHHDAGIVYLPDGGAYVLVLLSKN +LN-DFNKGTEQLAKISKTFYD-- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Actinomadura sp. 5-2 TaxID=1926885 RepID=A0A2P4UQS9_9ACTN +--------EDAFRAAGVAGWLHAEDVDTGRSV-RVRADEPVVLASVFKVPLLVAFFRQAA +AGLLDPAERVTLRPGDRAEGPTGTSILLDDVLSLRDLAALMITVSDNAAADALYDRVGGA +DAVNAVLAGLGLTATRITGDARELFAALNPVLTSRSTPREMAALLGLVWRDEAAPPAACA +QMRRMFGLQVW-PHRLSAGFPDDVRVGGKTGTLPT-IRNEIGVVEYPDGGRYAVAVFTRA +ARAALPQADAVIGAAARLAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Microbispora rosea TaxID=58117 RepID=A0A1N6TJE3_9ACTN +--------ERVFRSAGVTGWLHAVDIDDGREV-GLRADEPVVLASVFKVPLLLELQRQAE +RGLFDLTERVGVPAGDRTGGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLARV-GR +EAVNALLDGLGLTATRVVQNCREMLTALDPAVGNRSTPREMTRLLAMIWRDEAAGAASCA +AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +FGQNQPRADAAIGAAARMAIDQ- +>[subseq from] serine hydrolase n=1 Tax=Nonomuraea coxensis TaxID=404386 RepID=UPI00035D710A +-------FEALFRVAGVTGWLHAADLDTGREI-GHGADEPLPIASMFKVPLLAELCRQAD +AGLLDPAERVTVPAGDRSSPTGISAMLDDVTMSLRDLAYLMIAVSDNASADVLLRRV-GR +EAVNAMLASYGLDVTRVRRSSQEINDAFDPAWGNTSTPREMARLSGLIWRDEIASAASCA +WMRGVLNMQVW-PHRLASGFPDDVAVSGKTGTLPT-LRTESGVVEYPDGGRYAVAVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus panacihumi TaxID=497735 RepID=A0A3M8CRK3_9BACL +---LKKQLSQIVEDAKGTWGIVVEEVGQGICY-EHLPDQSFIAESVIKVPIMAAVFAAAW +QGEFSLEDRLVLRREDMVQGSGMLFALSPGLLSIRELATLMIIQSDNTATNILIDLV-GK +ERIDQTMRELGMKESRYVRKLMIYPADNPG--NNTITARDVTTVLSQLGAGRYLSAKACE +EMVAIMKKQQF-RNGLPSLLPTDWEIACKSGWDT-GRQHDAGLLYTQGR-CFAITALSQD +VE--AEEALHTLGSIGKAVYDY- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI0005C5F2A8 +--GLEEELQRIDAESPGELGVYIKHLGDDAQL-RYNAERFWYLGSAVKVPIAVALLQGID +DGEHRLDEQLSLQTEDKVDGSGDLVWQDEGVYSLRDLLTEMLIESDNTAANMLIRLV-GE +DELNQRTRKMGGDGFERITTFTQVRRRYYARKLNSSTLVAYGALLERLVRGELLSEASRD +VLYADMKIDSYDNYRLEAGLPEDVPFIHKTGTQLE-RACHVGVIEPRDEARAIVVAACAE +GLEEGKEAGQLFERVGQAIT--- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6I2Z5_9BACT +-kKLEARVAETADRIDGVMGVAILDLTDGRIL-LHNADRVFPTASSIKIAILLELYRQDQ +KEKSQLDDNYTFDPKDLVEDSRIMAGLTPGVVTNRDLAQFMVAVSDNAAANILIDRV-GK +DNVNAMLHGLGLSKTMLRRKMIDIAAARRG-DENVATPQEMARLLEAIYKGKALSKQATA +EFIKQLSTKKG--SYIPRYLPESVQVANKPGELE-AVRTDSGIVFCS------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Halomonas sp. TaxID=1486246 RepID=A0A651DFH0_HALSX +------------------------------------------------------------ +------------------------------------------------------------ +--AQALARTLGVTDTFAQPDYDGAFDAYEATGENVGTLSAFGDLLASLRGVQAVNAEQRQ +ALLDVMRRTSSGEQRLKAGMGKGISFAHKTGTQQR-RSCDAGIAERAAGAGAWVIVTCTR +GPLAVSAHERAMAGVGDAL---- +>[subseq from] Uncharacterized protein n=2 Tax=Sphingobium TaxID=165695 RepID=T0GJR1_9SPHN +--------------------------DEGWTV-SFNGGRMLPQQSVSKLWVAIAVMDAVD +HGALSLSDPVTVRRSDLTVHQPIRPLVTKAGTTIGKLLEMALTRSANSCNDVLLWKVGGP +EAIRAMLKRKRINDVGFGPGERKLQARYLANPYDGASANGVTLGLMLLKQGKLLSKSSTR +HLLSLMRASRTGPLRLRSGLRNGWTLAHKTGTGQTTGYNDVGILVSPEGHRYAVAVMIAS +TRAPIPARMRLMGDVTRAVIR-- +>[subseq from] Serine hydrolase n=2 Tax=Acidovorax sp. Leaf160 TaxID=1736280 RepID=A0A0Q5L797_9BURK +--ALQRELERAAAGGATPFGVYVRDLNTGESM-SFHASERWYLASSVKVPVAIAVLRGVE +RGAFTLDTPLTLRGSDYVDGAGPAKRPVGTALTVRWLLEQMIIYSDNTASDMLIGLV-GQ +PAVNAVAQEAVPGGLERITTLADVRRAYYATGLNSGRLDAYGELLAQLVEGRLLNPTHTR +YLLGVMERVKTGPQRIKAGLPSGTRFAHKTGTQR-ARTCDSGLVIVTPREARVIVVACTR +GEPSTARSDRTLRQVGIALC--- +>[subseq from] serine hydrolase n=1 Tax=Bacillus firmus TaxID=1399 RepID=UPI001331B050 +-hTLKAEILKLASCCEGRVAVYIHT-E-DGFI-EKDADAVFSSASLIKVPILLAGLSQAE +KGLLQLEEEVEVTASARVGGSGVLQAMARDLIKVTDLMTLMIIVSDNTATNLIIELL-GI +EKINQLFKDLGFNNTSLNRKMMDFE-ALKNGIDNTTTARDMAYGLKALAVQKLLSGKYTE +KALYILENQQFKNKLANTIDEEKVKVAGKTGELP-GIEHDCAIFTHKRK-TVCAAVLVDG +LQN-QAAGKEVLSAIGSRI---- +>[subseq from] Uncharacterized protein n=1 Tax=Phenylobacterium hankyongense TaxID=1813876 RepID=A0A328AUW3_9CAUL +------LLQAELARFPSKSGIYVKDLATGEEA-AVRGDEHFESASTIKIAVMVLAFRLAD +AGKLDLNARYTLRPEDYRGGSGVLRYDFGATPTVRDLITQMIITSDNTATDIMIRKVGGP +AAVNDFLRGSGYVALKLNKTLLDHFRARQNDVEDTVTPVELGRMLEGIERETVASPAACE +EMKRMLRAQQSGARKIPHFLT--VPVAHKTGENT-GVTHDMGMIYARSGT-IVMVSLNTG +ATGLIADADDRIGELARLVVDYf +>[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=UPI0005626E60 +----EKIIQDLLHETPYKVHLFVKNPKNEQFLfSHQIGEAFSSASIIKVPILLAALAYFE +KYSLSLHSSLPISPADWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM +EFLNDYFRQIGLQETLLQRKMMDVER-LAMGLDNFTSAWDMAHLFTRIYQQDLLAPPYNR +LVIDILNRQRA-HEGLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYSNSID-YLIGVFITN +VTEN-ELARQLIGRFSKVVYDH- +>[subseq from] serine hydrolase n=1 Tax=Pseudohongiella nitratireducens TaxID=1768907 RepID=UPI00083B99C4 +---LEAKVAEAEENIRLSIGVAGLATQEGRMT-FVGSPESYPPASTIKMLLIATLMQQVD +AGTLSLEDTATVEQSDIVGYGEIQNEPVPNEVTLGRLAELTVTISDNTATNVLVDVV-GY +EAMQALADELELETMQFGRKMFESP--MPPQKQNYINAEDTIQLLKQIYNDSFLTSQSRR +QIIAWMSAQTV-TTKIAAGVPEGMPIAHKTGENAS-VTHDLGYLLWPENE-VAVAIFAES +EVSDQAAVNPVVAAVAGIIYEH- +>[subseq from] Beta-lactamase family protein n=1 Tax=Micromonospora sp. CNZ299 TaxID=2035244 RepID=A0A2G6XHA6_9ACTN +-------------------GVTVRALSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVE +CGQVALDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLARYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Phycisphaeraceae bacterium TaxID=2026777 RepID=A0A2D5Z4I2_9BACT +----ERKLDEMLAAFPGRAGVVIRDLADGRTC-AREADHRFPTASVFKVPIMVELFRQVE +AGMHRFDDRHRIHRGLCRHGTHVDDCAVGTTWSLLDLCERMIVHSHDVATDLILDVI-GL +ESINRTMDALGFADTRVCMPIGRWHYYTDREHNNVTSARDMADMLERMRAGKLLNPAASK +QMLDMLHRCAH-RGMIPRHLDPKIPVAHKHGQSAR-IRADVGIVELPGR-PLIISVLTLA +VEGEARPGRELIAELSRQVV--- +>[subseq from] Beta-lactamase CARB-6 n=1 Tax=bacterium HR15 TaxID=2035410 RepID=A0A2H5WTX3_9BACT +--RLKAKLDAICERFRGVMGYSLYHTRYQHRL-NRLGDEIFPTASTIKTAVMAKAFEEIE +AGRLNYNESIPITPDDIRDGAGLLQFFREKQVPVKMLLHLMITVSDNTATVILARRL-GT +VEVNRYLERLGLKHTRLLMLHPELKELRDRWGMGMCTPNEMVELLDAIRTGKAGTPAACD +RMLRILSHQFY-DNLIASSVPPWVVAATKSGAIER-SRSDTGIVFSPSGA-YILAVYTKE +AESPDNEGEIAIREVAREVWRFy +>[subseq from] Serine hydrolase n=2 Tax=unclassified Sphingobacterium TaxID=2609468 RepID=A0A358XSI3_9SPHI +-kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE +KGELQLDQQLLYRSSQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG +IAINQLMSSLQLPHTRVNSQTEGRKPDWEKYGWGQTTPKEMADLVTLIRQGKVVSSKSSD +QMYRFMGNMFY-DERGLSQIPSTIKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN +NTGKTNEAEALTRKLSKLLWDYy +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7LJ47_9BACT +--TLRARLEARIAQAPAQVGLYYRSLARPDSI-LIGATLRLHAASTMKVPVMIQIFRDAD +AGLLELNDSLTVHTASLVQGAAFTYAVVGQNRSVRDLLELMITRSSNLATNILIERV-GA +SRAQASARSLGAWSIQVLRGVEDGA-AYRAGLNNTTTARDLGVLLGAIAAGRAASRAACD +SMLVILGRQEF-NEGIPAGVPSGTRVAHKTGWIGEVVYHDAGVVYPPHGGSYVLVVLTGG +IKED-SVAHNLVADVSRMVWE-- +>[subseq from] class A beta-lactamase n=1 Tax=Alistipes sp. Z76 TaxID=2304565 RepID=UPI00136C76A4 +-dALRDSISAIISDVTGEIGVAVI-IDSKDTV-TVNDIDKYALMSVFKMHQAVAICHSFD +LKGTPLDTIIEIDRTSLNPWSPMLKEHDNEHIPVSELLRYTLMQSDNNASNLMFDRLVSV +AETDSFIATIPRNSFRITERESDMQSDHSRSYNNHSSPLGVAMLVERLFTDSILSHEKQE +FICETVRSCSTGTDRIAAPLKDGITIAHKTGSGYINAHNDAAYITLPDGTSYTLVILVKD +FAGNEKQAAAIMARISDTVYQ-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudorhodoferax sp. Leaf265 TaxID=1736315 RepID=A0A0S9LRW1_9BURK +------------------------------------------------------------ +------------------------------------------------------------ +-RAEAVRRALELPPDALRTDIDAAYAGYYAEGHNSATLVGYGAMLERLVRGELLSRTSTE +RLVQAMKFGTRGNYRLEAGLPKNLRLIHKTGTQHQ-RACHMGVVQPQDGDATVVAVCAAE +LD-EQRAAGRLFEAVGRAIA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas straminea TaxID=47882 RepID=A0A1I1REX8_PSEOC +------------------------------------------------------------ +----------------------------------------------------------GP +QRVEAVANALDMKPEQLERDIDQAYRRYYESGLNSATLVAYGQLLGKLAKGELLSRPSTE +LLYDIMGLDSYEAYRLEAGLSEQLPFIQKTGTQR-GRACHMGIANPEGEDALVILACAEA +LDED-AEAGKLFERVGEAI---- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536CXJ6_9CHLR +------------SAIPGIAGAIALAE-DGTALyEHAADDEFPSASVIKVPLVMALYADAA +EGRIDLGERVAVGA--LVDGSGVLRYLADVRMTLRDLAMLAIIVSDNTATNRLIDRF-GL +ERVNDRLAAWGCSRTRLRRKMYDFDAA-AKGSENVTTPRETAALLLRLLRGGCRDRATSD +AVLAILERCQD-KTMLRRYLPPAAKVAHKTGTLDE-SRNDAAIVAVDRR--VVVSGFVRS +LR--------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=Q2FC56_STAEP +---HSKELNNLEKKYNANIGVYALDTKSGKEV-KYNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIIKEIGGI +KTIKKRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTF--------------- +------------------------------------------------------------ +----------------------- +>[subseq from] hypothetical protein n=1 Tax=Micromonospora inositola TaxID=47865 RepID=UPI0012FD723E +------QLARVAAGTNNRAGVTVRDLSGHQQI-AVNGTFRPKAASVIKLWILVELLRRVD +CGQLSLDRGVLVTRADVVGGTGKLKFAIPQVVTIHRLTEYMIEYSDNTAANVLIDQLGGF +APVNALIDSMNQRETVLAHKFFD--DANDRGGENYTSPDDVISLLGAVWDAQILTESSRD +LMIDFMRKQTL-NTKIPAALPPRTPLAHKTGDLSD-VSHDVGYCLTPRA-EIAVAFLTAG +PFQS---GSETVRQLARTVHD-- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7QNE2_9BACT +------------------------------YV-DLAADSSFHAASTMKVPVMIELFRRAN +TGSFGMNQGLLMVNQSLVDGSRYAYHRIGDRVSVDTLLRLMITRSSNFATNTLITLV-GA +EEVTRTMRALGAQRIQVLRGVEDGK-AFEKGLNNTTTARDLAIILRAIQEGKAASPPATR +EMLAILLAQEF-NEKIPAGLPPGTRVAHKTGEIT-AVSHDAAIVYPAGRKPYVLVVLTRG +IT-DGAKASKLIADLSSIIYQH- +>[subseq from] Serine hydrolase n=1 Tax=Pseudorhodoferax sp. Leaf267 TaxID=1736316 RepID=A0A0Q4XMZ6_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +RRVDAVRRALQLQPADLQRDIAEAYARYYASGRNSVSLVAYGGLLERLVRGELLAPAGTA +RLFKALKFETRGDYRLEAGLPPQVRFIHKTGTQFE-RACHMGVIDPQDGQAIVLAVCAAG +LD-EHRVAGRLFEQVGTAI---- +>[subseq from] serine hydrolase n=1 Tax=Nocardia xishanensis TaxID=238964 RepID=UPI00082FCE3B +---AEDRIRAVFADAGCSGWLHARRCDGSATEiSVGGDERVVLASVYKLPLFVAFCRHVD +SGRIDPATRLTVTPSDCTPPTGIAAMRDPVTMSLRDLATSMMTVSDNAAADVLLGET-GL +GAVESLVDDLGLTNTRIVGGTADLHRAYDPSYTSATTPEEMTRLLRALWSGTVLSAEQTE +FVRTVMRHQVW-PHRVAAGFPRSVSTAGKTGTIGV-IRNEVAVVEFPGEYPVAVAIFTRA +ARADLPVVDAAIAETARIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Cyclobacteriaceae bacterium CUG 91308 TaxID=2483804 RepID=UPI00131DC7E5 +--DLKNTILGNISEIKGNFAIAFHNLATSEQL-LINEKEVFHAASTMKTPVMIEIYKQAA +EGSFDLSDSIPIINEFKSIYDGSLYNQIGQKTTIYELMYQMITKSSNLATNILIEKV-DA +KKVTQTMRDLGAADIEVLRGVEDQK-AYDADMSNTVTAFDLMVILEAIASGKAVNQEASS +HMLVILSDQYF-NDLIPKYLPEGVKVAHKTGSIT-GVQHDSAIVELADGNRYVLVILSKN +LT-DVPKGKEAIAQISKLIYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Muricauda zhangzhouensis TaxID=1073328 RepID=A0A1H2SEW6_9FLAO +-eALETKIRTQIDSIEGDVAVALLNLAEPSDTlFINESEEFHAASTMKVPVMIELFKQQA +SGKINLNDSILLINESIVDSSPYSYSKINTNVALKDLMYSMITVSSNLATNVLIELV-DA +KKVTATMRDLGADKIEVLRGVEDQK-AYDLGLSNSTTAKDLLIIMQAIATNKAGTETDCE +AMINILKDQQF-NEIIPHELPDNVEVAHKTGSIT-GVHHDAGIVYLPDGRSYVLVLLSKN +LK-DFDKGTEQLAGISKTIYDY- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A2T4X2J5_9BACT +---LKTNIEQQIETIEGDIAVGFLDLSEGNSI-LINVDEEFHAASTMKVPVMMELFKQQN +EGLINLNDSIVLVNESIVDGSLYSYSKIGTKQTLYDLIIPMITVSSNLATNVLIEIV-DP +KKVTNTMRELGAEHIEVLRGVEDQK-AYDLGLSNTATATDLMIIMKAIANGNAGTEEDCE +AMISILKDQKW-NDMIPLYLPTDVKVAHKTGTIT-GVHHDAAIVYPPNGKSYILVLMSKN +LK-DFDQGTEQLAKISKTIYNY- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5J1S7_9BACT +--TLNEQLERLSAQSKAQIAVAVHDLESGLRF-SLEGDRWFHAASTIKVAVLLALFRAAD +EGRVRLDDSLHVRNRFISAASSFHYQAIGRTAKISALAEGMIAVSSNLATNLLLDLV-GV +EYARKVLRDAQVEGVELRRGVED-HAAHERRINNEATANGLLTLLSAL-RGDFLSSESKE +QAIRILLEQRF-NSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DL-EQNGRRETVAAISEAIYR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga japonensis TaxID=104662 RepID=A0A562T8A3_CHIJA +--RLAAKLRPLLARHHGIAGIYVHHLKTNRVV-AINADTLFPTASTIKVPIMIGIFDRIE +KGELQYRQPLVYRDSLLYEGEDILGSFKDGEIGLDKVMMLMLTMSDNTASLWLQSLAGGG +QQINAWLEAQGFTHTRVNSRTPGREENRRQYGWGQTTPREMARLLEMIYKGEVVSKAASE +RMYRNLTRNYW-DTEGLLQVPPGVRTASKNGAVN-ASRSEVVMVNAPHGD-YVYSIITKE +NQERDNEAWELLRRVAGLIWQHy +>[subseq from] Serine hydrolase n=1 Tax=Ignavibacteriales bacterium TaxID=2049428 RepID=A0A419EZ96_9BACT +---------TEISTIKGDVAVAFLNLNTSDSL-LINENENFHAASTMKTPVMIEVYKQDA +SGKFKLSDSITVHNESIVDGSIFKYANIGKQLTIKELVYDMITVSGNLSTNILMEIV-KA +ENVTKSMRELGAQKINVLRGVEDIK-AYEKGLSNTTTAKDLMIIFENIANYKIVSEDVCR +QMIDILLAQKF-NNIIPANLPKDVVVAHKTGSID-GIQHDSGIVYLPGGKKYVLVLLSKN +LE-SNVKAIPVLANISKLFYDY- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI001328F413 +---VEGTIRDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNGN-HTKLPHDLPTEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7JV20_9BACT +-qDLAARIAARIAQTNQGVGVYYRRLDRPDSL-LVDARHRFHAASTMKVPVMIEVFRDAD +AGTLRLSDSLTVVNESIVDGSPYQYLRVGQKASVRDLLELMITVSSNLATDILIERV-GP +ARANATAHALGADSILVLRGVEDGV-AYRAGRNNTTTARDLGVLLAAIAEHRAASRVACD +SMLAILGRQHF-TEGIPAGLPPGARVYHKTGWVGQVVYHDAAYIEMPDGRRYVLVVTTGG +IQLD-TAAYNLVADVSRIIA--- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI0013310F42 +---VEGTIRDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNGN-HTKLPHDLPTEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] serine hydrolase n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI000235B27A +---VEGTIRDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNGN-HTKLPHDLPTEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] serine hydrolase n=1 Tax=Pseudorhodoferax sp. Leaf265 TaxID=1736315 RepID=UPI0009EA7088 +--RLTNALERIDAMPGPRIGVYVRALASGESA-SFRAGQSWYLASAVKVPVAIAVLRGIA +RGDYQLDTPVTLRADDYVDGAGATNRHAVGALPIRFLLEQMVIHSDNTASDMLIGLV-GL +EQVNAVTAEVAPAGFGPITRLAEVRRAYYATGLNAGRLDAYGELLVQLADGRLLPPAHTR +YLLGLMERVVTGSQRIRAGLPAGARFAHKTGTQR-GRFCDAGIVQPAAGTRVVV-VACTR +GALSLARAERALREVGAALC--- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DD94F2C +------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQVFLDDGVLVTPQDVVGGTGQLQFETPQVVTLHRLTQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] hypothetical protein n=1 Tax=Rubrobacter aplysinae TaxID=909625 RepID=UPI00128DAE30 +------EVRKIVEDYEGTVGVYVQDKSGDWGY-GIRPDERFYAASVIKLPVMAAVYRKIE +AEELSLDETVATEDRDYAGGAGGLQWQEESVHTVSDYLWMMVKQSDNVATNLLVRTVGGP +GYVNEVANDLGAENTEIHNKVTDQRAAAPG-LDNYTTPRDMAEILSGIASGEAANEAHTG +EMLGLMRQNGP-ESWVGGDLPPEAEPACKVGWIN-GVYNDICLVQTEGE-PYIISVFSKY +GPPRVAPGVSTLGGISEEVW--- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium pseudoshottsii JCM 15466 TaxID=1136880 RepID=A0A117DVY9_9MYCO +--DLESRFAELEQKYEARLGVYVPGTDATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYS +--IAHLGTVITYNSADIRSTSPITEQHLATGMSIGGLCDATIRYSDGTAANLLLQDIGGI +AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTP---------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=2 Tax=Paenibacillus elgii TaxID=189691 RepID=A0A163TDJ6_9BACL +-nQLEATIHQAASSVEGKVGIAV-DTAEGQIR--IHADELFPSASLIKIPILLEAYRQAQ +EGRLDLHQPYAVPSGERVGGTGVIHQLSGALLSLQDLMALMIIVSDNTATNMIIDLI-GM +GTVNKLSDGLGCGATVLGRKMLDFQAK-RNGKDNFTSPRDMIIFLKEIVDGSTLKQEAKD +AALQLLRNQQF-NAKLPARIIDKPVLAHKTGELP-GTEHDAGILQVNGK-TAYIAVLTTN +LV-DNLPAQQVISTIGKAVFDY- +>[subseq from] serine hydrolase n=1 Tax=Thermoactinomyces daqus TaxID=1329516 RepID=UPI00051A7CE6 +-qKLTQKLDDWKTGVGGTWGIWIEDLHTEQRW-SWNEAKTFYSASIIKVPIMIAVYRQAD +RGALELSREVILRKEDQVGGSGVLQHLTPGTFTVKDLVTLMIIQSDNTATNLLIDLL-GK +NVIRETMNELGMTGSTFYNKLMILPANPEG--INQITAEDMARVYKALATGKAISWHASQ +EMVQILKKQQL-NDCFPYFLPSKYEMAHKTGMVTR-ILHDSGIFYIGSRA-LILVALSEG +LN--YHEAQKGLGELARLAFDVy +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. 40-24 TaxID=1895843 RepID=A0A1Q4G7D9_9SPHI +-kKLKSQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE +KGELQLDQQLLYRSSQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG +IAINQLMSSLQLPHTRVNSQTEGRKPDWEKYGWGQTTPKEMADLVTLIRQGKVVSSKSSD +QMYRFMGNMFY-DERGLSQIPSTIKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN +NTGKTNEAEALTRKLSKLLWDYy +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI0006B48850 +---VEGTIRDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMVAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNGN-HTKLPHDLPTEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QIN------------- +>[subseq from] Serine hydrolase n=2 Tax=Lactobacillus sp. CBA3605 TaxID=2099788 RepID=A0A2R3JMF6_9LACO +--SIKQAINTSLSGLKGTTSVAVAATDSSAKV--VQNDQSQRAASLIKLFILITAYHQVD +SDQLNLDESYTLTANDKVGGTGTLQGLPTGSLSYREILKRMMDESDNTAANIMIDKVGGI +STINAEIERLDLSETQLERKMMDTA-ALADGKDNYTSVTDVATVLTKMYSGKLISRTADQ +AMLTIMRQNAN-HAKLPHDLPSDAIVYNKTGEYDYGVQNDAAIIKNTQGA-FVVVVLSQD +GDETE--QVT------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. TaxID=341027 RepID=A0A3B9NDB7_9SPHI +-kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE +KGELQLDQQLLYRSSQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG +IAINQLMSSLQLPHTRVNSQTEGRKPDWEKYGWGQTTPKEMADLVTLIRQGKVVSSKSSD +QMYRFMGNMFY-DERGLSQIPSTIQTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN +NTGKTNEAEALTRKLSKLLWDYy +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6I8N6_9BACT +---LTEQVERLTAESKARTAVSLHDLESGLRF-SLRGDRWFHAASTIKVAVLLALFRAVD +EGRVRLDDSLHVRNRFFSAGSPFQYQAIGRTAKISALAAGMITASSNLATNLLLDFL-GV +AYARNVLRDAQVQGVELRRGVEDH-AAHEKGINNEATADGLVTLLSAL-RGDFLRSESKE +QAIRILLEQRF-NSMIPAGLPPHAAVAHKTGEIST-ACHDMGIIYLPEREPYIAVILTEF +DS-EKEGRRETVAAISEAIYH-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Melainabacteria bacterium RIFCSPHIGHO2_02_FULL_34_12 TaxID=1801607 RepID=A0A1F6RCW6_9BACT +------QIKQKIRQYSLVCGVYIKPSWTETSI-NINGEAQFPAASLIKIPVAVVLLRNID +KGLIKWDTVLTLKPKHYAQGAGYLRKRAGTKLELREVFKLMITISDNTATNMIIDLLGGI +NKVNQEILKLGLKNTRLVNYLGDFKGT------NKTSPHDLAELFEKSLEGELLSSNSRK +IFKNTLLKVKN-KSLIKKGLGKFTKFAHKTGTIGI-CVGDAGIVYLPLWKRVTISIIVRR +PFNS-LQGQRIIREITQIVRE-- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI0011B39D24 +--TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITVYQQVN +EGKLNLNDKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM +DKVNAQIKKTGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN +AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD +GSRDEQ----------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax radicis TaxID=758826 RepID=A0A561D1L5_9BURK +------------------------------------------------------------ +-------------------------------------------------------PM-GP +QRVDALARTIEVDKADFRKTMDEAYQRYYARGLNSAPLTSYGGMLEKLVTGKLLSPAHQQ +RLFTDLKYATYDAYRLEAGLPRSERFIHKTGTQLH-RACHMGVVNPQDGGRAAIVVATCA +EDDEHGEAGKAFEQIGRAVT--- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas daroniae TaxID=2487519 RepID=UPI0010385DAE +------------------------------------------------------------ +----------------------------------------------------------GP +LRVEAVANALELKTDQLDRDLDEAYRRYYDSGLNSATLIAYGQLLGKLVSGDLLSRESQE +RLYDIMGLDSYDAYRLEAGLAKDLPFIQKTGTQQH-RACHIGVANPQDENALVIVACAEG +LDEN-DEAGKLFEQVGEAI---- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas sp. AG1028 TaxID=2572911 RepID=A0A561DWS6_9PSED +------------------------------------------------------------ +----------------------------------------------------------GP +QRVEAVANALDMKPEQLERDIDQAYRRYYESGLNSATLVAYGQLLGKLAKGELLSRPSTE +LLYDIMGLDSYEAYRLEAGLSEQLPFIQKTGTQR-GRACHMGIANPEGEDALVILACAEA +LDED-AEAGKLFERVGEAI---- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5TDK3_9BACT +--TLAEELERLTAESKARAAVAVHDLESGLRF-SLRGDRWFHAASTIKVAVLFAVFRAAD +EGRLQLDDSLHVRNRFISAGSPFHYGLIGRTAKVSVLAKEMISASSNLATNLLLDFV-GV +EYARKVLQDAQVSGVELRRGVED-HAAHEREINNEVTASGLLTLLSAI-RGDFLSNKSKE +QVIRILLEQRF-KSMIPAGLPPHATVAHKTGEIST-ACHDMGIVYLPERAPYIAVILTEF +DS-EREGRRETVAAISEAIYR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Pediococcus pentosaceus (strain ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w) TaxID=278197 RepID=Q03I06_PEDPA +--TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN +EGKLNLNDKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM +DKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN +AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD +GSRDEQ----------------- +>[subseq from] serine hydrolase n=1 Tax=Sphingobacterium sp. G1-14 TaxID=2003121 RepID=UPI000B49380C +-kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE +KGELQLDQQLLYRASQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG +VAINKLMSDLQLAQTRVNSQTEGRKPDWERYGWGQTTPKEMADLVTLIRQGKVVSPKSSD +QMYRFMGNMFY-DERGLSQIPSTVKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN +NVGKTNEAEELTRKLSKLLWDYy +>[subseq from] Beta-lactamase n=2 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=W7RTH9_LYSSH +----EKIIQDLLHETPYKVHLFVKNPKNEQFLfSHQIGEAFSSASIIKVPILLAALAYFE +KYSISLHSSLPISPADWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM +EFLNDYFRQIGLQETLLQRKMMDVER-LAMGLDNFTSAWDMAHLFTRIYQQDLLAPPYNR +LVIDILNRQRA-HEGLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYSNSID-YLIGVFITN +VTEN-ELARQLIGRFSKVVYDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. OV194 TaxID=1881065 RepID=A0A1I2BC82_9BACI +--ELNNRVNDIISGQNGAYA---YWIETKDGHiEFQADEVFPAASLIKIPILIEAFRQTE +AGQIDLASRISLKQEVRVGGAGVLQLFSDESVTVADILTLMITVSDNMAANIMIEKT-GM +ERINDLLAELGCSQTVLQRKLMDFEA-VKQGKNNYTSARDVILQLKEIDRGGRLKDKSSQ +TILHILQNQQF-RYKLPAYMDEKITIANKTGELD-GVEHDAGIFTFKRE-KLFAAVLTKN +LP-SEAEGRQALALIGKALND-- +>[subseq from] Class A beta-lactamase n=1 Tax=Azospirillum sp. TaxID=34012 RepID=A0A316T3U2_9PROT +-------------GSGSRVGIAVLS---GDKV-LTVGKGAMPLMSVFKMFVALNVLEHQE +-----KDKVLIVTEEMINRYSPMLKDYPVVPISVAELLKYMVSASDNNATDILLAFGGDI +RATQDYVRGLGFPGIVLKVNEQEMHENIRNQYLNRAVPADVVKLLRVVRESELLTNENKR +FFEALMTETVTGADKIKKYLPSNVVVGHKTGSSDNGADNDVGFVRLPDGREYYLGVMIAD +SPMSDRDNAELIARISKIVYRHf +>[subseq from] serine hydrolase n=1 Tax=Salegentibacter sediminis TaxID=1930251 RepID=UPI0009BCFF20 +---FQEKIDSIFTESQGDFALAFKELSGEKGSiFINEHENFHAASTMKTPVMIEVFKQAE +AGKFSLDDSLLIKNESIFDGSSFKYSQIGKKISIKDLVIDMISQSSNLATNILIELV-DA +KEVNASMRKIGARDINVLRGVEDMK-AYEAGLSNSTTAYDLMLIFEALANGQAVNPEADK +EMLEILRLQQH-TDLIPALLPKEVKIANKTGWIT-GVHHDSALVELPDGRKYVLVLLSKN +MK-EMEKGTQMLSGISKMIYD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC58_STAAU +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVS +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTF--------------- +------------------------------------------------------------ +----------------------- +>[subseq from] zinc_ribbon_2 domain-containing protein n=1 Tax=Pediococcus acidilactici DSM 20284 TaxID=862514 RepID=E0NH64_PEDAC +---VEGTIRDAFGDISGDNAVYVSPVDSDTEV-DFN-DQPQRAASDIKLFVMIAAYQQVK +DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM +AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE +EMLTILKQNGN-HTKLPHDLPTEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD +GQRDE--QINAM----------- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas daroniae TaxID=2487519 RepID=A0A4Q9QN87_9PSED +------------------------------------------------------------ +--------------------------------------------------------L-GP +LRVEAVANALELKTDQLDRDLDEAYRRYYDSGLNSATLIAYGQLLGKLVSGDLLSRESQE +RLYDIMGLDSYDAYRLEAGLAKDLPFIQKTGTQQH-RACHIGVANPQDENALVIVACAEG +LDEN-DEAGKLFEQVGEAI---- +>[subseq from] serine hydrolase n=1 Tax=Lutibacter sp. SM1352 TaxID=1548456 RepID=UPI000E513B88 +-eNLETTILSQIDSIDGTVAVAFFNLSAPEGSlFINVDEKFHAASTMKVPVMIELFKQAA +EEKFNLNDSILLKNESIVDSSLYSYNKIGSKVVISDLMYNMITVSSNLATNVLIELV-DA +KKVTATMRDLGAEHIEVLRGVEDQK-AYDKGLSNSTTARDLMLIMKAIANDRAGSQKDCA +SMLTILKNQQF-NDMIPLYLPKEVKVAHKTGSIT-GVHHDAGIVYLPNGRTYVLVLLSKN +LK-DFDKGTDQLAKISKTIYDY- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7XUX1_9BACT +-----------------SLGIAFYDAQATIQW-AYNGDQYFHAASTMKLAVLLAVFRQVD +RGELGLDAPVHVRNRSIVNQEPFMYGHLGRTLTIRELAYWMITKSSNLATNLLVDVV-GI +QTIQHALDELDIDGVRILRGVEDQ-AAFDAGLNNEVTANGLLKLLRLIAEERAYSKNASD +EMLNILLEQQY-RGGIPAGLPKAARVAHKTGNIST-VHHDAGIVFIEDRKPYVLVILTQF +RAE--TGRGTAVADVSRDIYN-- +>[subseq from] Beta-lactamase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A174QP24_9CLOT +------NVTDQIKALPGKTGFYYENLVTGERA-AYHEEERMMAASVIKLFVMTEAFTRFE +EGTLSPDRIIRMRREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTATNVLIDLL-GI +EEINRTIRRLGYRDTVLRRKMYDTEKS-KQGIQNYITAAETGRLLREMYQGRLVSRTASE +AMISILKNQQL-CSKIPQALPEEPEIAHKTGEDC-GITHDVGIIYAKQ--P-FIVCYCGN +DT-DTPAYERVMAETALWLY--- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6E920_9BACT +--TLREALEKLARESKARVAVALLDLESGFRF-SLAGDRWFHAASTIKLAVLLAIFRAAD +EGRLRLDDSLHVRNHFVSAGSPFRYQAIGRTAKISALTEGMIVASSNLATNLLLDCL-GV +EYARNVLRNAQVSGVELRRGVEDQ-AAHEKGIDNEATADGLLTLLSAL-RGDFLKKESKE +QAIHVLLAQRF-NSMIPAGLPAHATVAHKTGEIST-ACHDVGIVYLPEREPYIAVILTEF +DA-EQNGRRETVAAISEVIYR-- +>[subseq from] Serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A411SZN1_ALCFA +-eRLQERLEPVLAQEAARISMAVYATDGTSLF-EWHAQRVMPSASLIKTPMLLCLLEQVA +QGRLSLDTVYPLPEGDRTPGTGILSQLPGVTLSLRELALLMIILSDNVATNALIDLL-GM +ANINAWCAQAGLQQTQLQRHMMDMKAR-EAGKDNWTTAQDACSTLLYLLGSPALPESLRQ +QGLDMLADQRE-RGHFAAILPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG +FT--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Paenibacillus sp. N2SHLJ1 TaxID=2527873 RepID=A0A4Q9DPW2_9BACL +-eQLAQNITNLVRQAGGVWGIAVEDLQSGERF-GLNEHGGFMAASLIKLPIMAAVYAAAY +EGRLRLDDQVSLRAGDKAGGSGILQHMAPGMMSIKDLITLMIIQSDNTATNMLIDLI-GP +EPIRRTMLDLGMQQSVFANKTGLFLTDPPG--QNITTAADVSLLLRKLASGSFISRHACA +DMIAVMKLQQL-GNGLAERLPPEWQWAGKTGSLT-GIAHEAGVLYVGHR-SIIVSVLSES +TAN-PGDVRKMISSIGEQV---- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. MUM 13 TaxID=1678001 RepID=A0A1S2R5C0_9BACI +--NLQKKIESHIAEFPGRISYKID---SADQFiQKDAAECFQAASLIKIPIIMEGFRQIE +EGKMYLNERAEISDSDLAGGSGVLHALSKSGFTIEDMLTLMIIVSDNTATNMLIRKM-GI +NSIHQTIASLNLKKTVLGRYMMDFD-AIGKGFDNYTCADDMVTCLRSIHQGSFLSGESRR +HIIRIMEKQQL-VSKLPAMMNNEVTVASKNGAIP-GAEHDSAIITRGDVT--VYAAVLTD +SLESEEDGRRIISQIGRYIYEE- +>[subseq from] serine hydrolase n=1 Tax=Echinicola pacifica TaxID=346377 RepID=UPI0003778B57 +--DLEAQITSHFAEVQGDFALAFELLDEDSIRlLINDKAIFHAASTMKTPVMIELFKQVE +SGNLSMDDSVKVINQSIVDGSPYKYHRIGKNSTYRELNYEMITRSSNLATNILIEKL-DA +KNISHTMRELGAMDIEVLRGVEDLKA-FDRGLSNTTNAYDLMLIMKAIATGKAVSKSASE +SMIKILEDQHF-RTLIPRLLPKEVIVAHKTGGIT-GVRHDSAIVTLPDGRQYVLVILSKN +LS-DEPAGEQLISEVSRMIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Armatimonadetes bacterium TaxID=2033014 RepID=A0A3M2B5D7_9BACT +---LKAKLDAICEKFRGVMGYSLYHTQHNHHI-DNHGDTIFPTASTIKVAVMSKAMEEID +AGRLGYADKLPITPDDIREGSGLLQFFKENQVEVKMLLHLMITVSDNTATIMLARRL-GT +VEVNRHLERLGLRNTKLLALHPELKALREKWGMGMCTPNEMVQLLDAIRTGRAASPAACE +RMLRIMSHQYY-DDLIGSSVPPWVVACLKSGAVNR-SRSDVGIVYAPSGA-YILAVYTKE +NETPDNEGEVAIREVAREVWRFy +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000750463F +-eRLQERLEPVLAQEAARISMAVYATDGTSLF-EWHAQRVMPSASLIKTPMLLCLLEQVA +QGRLSLDTVYPLPEGDRTPGTGILSQLPGVTLSLRELALLMIILSDNVATNALIDLL-GM +ANINAWCAQAGLQQTQLQRHMMDMKAR-EAGKDNWTTAQDACSTLLYLLGSPALPESLRQ +QGLDMLADQRE-RGHFAAILPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG +FT--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. UMB0893 TaxID=2066053 RepID=A0A2N5FLB7_9BACI +-----LKLQELIDRYQGRVGLSLEL--DGDLY-EWNSTQVFPSASLIKLPILLTAFRQKE +QGILDFDEIVTIAEMKMTSGAGVLQALSESALSIADMVTLMIIVSDNMATNLLINKI-GV +SKVRDFMDELNLSGTELNRQMMDFA-AIDKGLNNWTTPSDMLKCLKAIGQNGFLSDESRG +QIAAILQKQQFTDKLSFLMDTEKIVIGSKTGELH-GVEHDCAIIQFKERT-VYAAVLMDE +IV-DKRYGRSTINEIGRLIYEE- +>[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2D6PZC0_9BACT +--ALDESVEALCVQHGTDVCIAYANLDTGRVW-MRFGDLVLHAASTMKIAVMYEAFRQHD +AGRLDLDAPVEVRNESIVDGSPYAYEHVGARLPARELVRRMMVRSSNLATNLMVEIL-GP +KSIQATLTSLGLRDMKVLRGVEDGP-AFERGLNNVATARDLMTLLREVHAGRSVTGASRA +AMREILLGQEF-NDLIPKGVPPDTAVAHKTGSITR-IRHDAAIVSPVNGPAYVLVVLTRG +FD-DRDAAAPVITEVSRLVWMH- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium detergens TaxID=1145106 RepID=A0A420ADJ6_9SPHI +-kKLEKQIKQLIQGFQGEVGIYVHDLKKHKEV-NIGADSIFPTASVVKIPILVGVFDKIE +KGQLQLDQEYVYRESQKYGGSGLMQFFKDSSVDLKTLVALMLSYSDNVTSIWNQKLAGGG +IAINKLMSDLQLQHTRVNSQTEGRKADWEKYGWGQTTAKEMADLLTLIRQGKVVSVKSSD +RMYRFLGNMFY-DERALSQIPATVKAASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN +NQGKTNAAEVLTRNLSKLLWDYy +>[subseq from] Class A beta-lactamase n=1 Tax=Muribaculaceae bacterium TaxID=2498093 RepID=A0A4S4GH27_9BACT +---LKEKLTQYIADKNARIGIAVL-VNGRYSV-SINGDYAFPMLSVYKFPIAMAVAEYCR +MRDIDFSDSCLVTAGDLHRYSPMLKKYADVDITFDELLAYALQQSDNNASDILLNCIGGA +ASANEYVSATGIEGVTIKWSEDDMHIDVSRCYENSATPVAMAKLMWTFDS--QYNDTLSK +RIKQLMESCETGQARLAKPLESNAVIGHKTGTGFINAVNDAGYVHLPDGTHYSIAVFIAD +SYYDMEHTEDIIADISEMTA--- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI000853C6F6 +--TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN +EGKLNLNDKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM +DKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN +AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD +GSRDEQ----------------- +>[subseq from] serine hydrolase n=1 Tax=Nonomuraea candida TaxID=359159 RepID=UPI0005BA7D51 +------AFESLFRAAGVTGWLYATDIDTGHEV-GRGADEPLPTASMYKVALLIALCRQAE +AGVLDLAARVTVTAADRVTGPTGLSAMLDDVISLRDLAYLMIAVSDNTSADKLLALV-GF +DAVNGMLAEFGLKDTRVVQGAGEMNAALDPARANCSTPREMARLFAMIWRDEAASPESCA +WMRTVLNMQVW-PHRLASGFPDDVAVSGKTGTLPT-LRCESGVVEYPDGARYAVSVFTRS +FSTAQPRADAVIGTAARMAVDH- +>[subseq from] Zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=A0A5R9BQD8_PEDPE +--TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN +EGKLNLNDKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM +AKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN +AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD +GSRDEQ----------------- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. FJAT-26652 TaxID=1684141 RepID=UPI0006A78D33 +-nELNNRVNDIISGQNGDYAYWIE-TEDG-HI-EFQADEVFPAASLIKIPILIEAFRQTE +AGQIDLASRISLKQEVRVGGAGVLQLFSDESVTVADILTLMITVSDNMAANIIIEKT-GM +ERINDLLAELGCSQTVLQRKLMDFEA-VKQGKNNYTSARDVILQLKEIDRGGRLKDKSSQ +TILHILQNQQF-RYKLPAYMDEKITIANKTGELD-GVEHDAGIFTFKRE-KLFAAVLTKN +LP-SEAEGRQALALIGKALND-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium cochlearium TaxID=1494 RepID=UPI000BBCB50F +-----------------------------------NEYMVFPSASTIKLLIMARIMKEVK +EKKRNLEDKIILKDVYKCGGDGILKELNDGHFTLKEVITLMIIVSDNTATNILIDMI-GM +DNINCMGKELGLTNTELRRKMMDSE-AVKMGRENVTTAKDLSCILEMIYNRQLVDCEYSD +IMLDILKKQQV-TGRLDLYLPEDILIAHKTGDLDN-LEHDVGIVYHPRGN-YLICVLTKN +VS-TNKYGREIIGEISQKVYN-- +>[subseq from] Uncharacterized protein n=2 Tax=Fictibacillus phosphorivorans TaxID=1221500 RepID=A0A160IMD3_9BACI +-kQMERSLSDLLASGKGVYGCSLFDFNTKENF-TYHENESFYAASIIKVPIMAAVFAHAF +EGKYRLKDKVYIQDEDFVPGDGVLKHLSAGMWTIHDLLVLMIIESDNTATNVLIDLV-GK +ENVHAYMKEWGFKTSHLHHKLQISPDRIPG-EFNVITPHEINAFLILIATGRVVSIKACE +MMINILKQQKM-NDLLPRYLPASWEAAHKTGYVS-GVEHNVGLFYFPGHT-YAISVLSKN +VP-DRNEPRVIMGQIGHLLF--- +>[subseq from] Beta-lactamase class A n=1 Tax=Laceyella sacchari TaxID=37482 RepID=A0A4R4AQM7_LACSH +--RLIQNLEHWKSNAVGNWGVWIEDLTSGTTW-VWNETKSFYAASIIKVPIMVAVYKQAF +LGRLALADEIILTAEDQVGGTGVLQHLSPGLLSVQDLTTLMIIQSDNTATNILIDLL-GT +ETIRETMDELGMRKSTFYNKLMIVPAAPAG--LNMITAADVAQCFRHIALGKAVSQYASR +QMVEILKKQQL-RDCFPTGLPSQWELAHKTGMVTQ-TLHDAGILYTKSRA-MVMVALSEE +CE--YEQAQQQMKQLARLVYE-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. M46 TaxID=2152717 RepID=A0A363NLE4_9SPHI +-rKLEKQIKQLIQGFQGEVGIYVHNLKKHKEV-NIGADSIFPTASVVKIPILVGVFDKIE +KGQLQLDQELIYRESQKYGGSGLMQFFKDSSVDLKTLVALMLSYSDNVTSIWNQKLAGGG +MAINTLMADLQLQHTRVNSQTEGRKTDWEKYGWGQTTPKEMADLLTLIRQGKVISEKSSD +RMYRFLGNMFY-DERGLSQIPATVKAASKTGSLDD-VRNEVMLVNAPKGD-YVFSIFTKN +NGGKTNAAEILTRKLSKLLWDYy +>[subseq from] Putative Beta-lactamase n=1 Tax=mine drainage metagenome TaxID=410659 RepID=E6PD01_9ZZZZ +--ALRDSLHSLALSSDANVGIAVEDLATGAIT-GYNLNRSMPAASTIKIPVMVEVFRQMA +RGRFTLTHVMHLRVQDRDYGSGDLAYAPGAPVTVKRLLSEMIDVSDNTAANMLIRLV-GR +QRINAAMQAYGCHHTYLRTAIRTNVSSV--ETNLRTTPLDMLTLLVRMAHGKLVDTWSSH +AMLEILAHQEI-DTLLPEPLPDGTTIAHKTGSLHD-VMADVGIVYEPGA-PFAIAAMTSG +LPD-PQLGRDIVRQA-------- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5UE11_9BACT +-kKLEARVAETADRIDGVTGVAILDLTDGRIL-LHNADRVFPTASSIKIAILLELYRQDQ +KEKSQLDDNYTFDPKDLVEDSRIMAGLTPGVVTNRDLAQFMVAVSDNAAANILIDRV-GK +DNVNAMLHGLGLSKTMLRRKMIDIAAARRG-DENVATPQEMARLLEAIYKGKALSKQATA +EFIKQLSTKKG--SYIPRYLPESVQVANKPGELE-AVRTDSGIVFCS------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7L2W3_9BACT +----RDRLEVRIARAAQAVGLYYRSLTRPDSV-LIGANLRLHAASTMKVPVMIQIFRDAD +AGLLRLDDSLTVHTASLVPGAAFTYAVVGRNRSVRELLELMITRSSNLATNILIERV-GA +SRAQASARSLGAWSIQVLRGVEDGA-AYRAGLSNTTTARDLGVLLAAIAAGRAASRAACD +SMLAILGRQEF-NEGIPVGVPPGTRVAHKTGWIGEVVYHDAGVVYPPDGGSYVLVVLTGG +IKED-SVAHNLVADLSRLVYE-- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI00066AE1D6 +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMQEKLVRGELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] serine hydrolase n=1 Tax=Alicyclobacillus macrosporangiidus TaxID=392015 RepID=UPI00068D69E7 +-tELSQRIHGLVSTLRGMCSVAIES-KEGNIY--VRADDRVPAASLIKIPILLEGLRQVH +AGRVSLEQPIRISDVEVVWGTGIIQLMSRNIWTFRDLLTLMIIVSDNTATNVIIDML-GM +ERVNALASDLGCSNTVLARKMMDFQAR-KEGLDNFTSAREVLVFLKEMVSGNTLPDSMKD +LARQIMAGQQL-NHKLPGDIPRDMEIAHKTGELR-GIEHDAGIITFGGN-RVYAAVLTWD +MEE-NAAGQRLIAAVGRAVFDY- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536IPT8_9CHLR +----------------GIAGAIALA-EDGTALyEHAADDEFPSASVIKVPLVMALYADAA +EGRIDLGERVAVGA--LVDGSGVLRYLADVRMTLRDLAMLAIIVSDNTATNRLIDRF-GL +ERVNDRLAAWGCSRTRLRRKMYDFDAA-AKGSENVTTPRETAALLLRLLRGGCRDRATSD +AVLAILERCQD-KTMLRRYLPPAAKVAHKTGTLDE-SRNDAAIVAVDRR--VVVSGFVRS +LR--------------------- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plajomi TaxID=1457217 RepID=UPI0010F6EA0A +--AVQKTVTTTMGGLSGKTAVAVMPLSGQPAV--IWHNQPQRAASVIKLYILATVYQRVA +AGKLDLDQHYVLKTSDQVGGSGTLQSLPAGTLTYRDVTQRMITVSDNAASNIMIHAVGGL +DAVNAEIKALGLRQTKLNRYLMDTA-ALKAGHDNVTSVSDVASLLRRLANHQLVSARASR +AMLAILKQTAN-HTKLPHALPAAATVYNKTGEFDYGVQNDAAIIQNQRGT-IIVVVLAEA +GQ--REAQINAMSDLGRALYEQ- +>[subseq from] serine hydrolase n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=UPI0009DB9FC2 +------------------------------------------------------------ +---------------------------------------------------------NGP +ARVEAIRRAADVKRTELATTMDEAYDRYYRRDLNTTTLIAYGAMLERLVRGQVLPDAPRA +LLYKAMKHDIYTGYRLQAGLPRDHAFIHKTGTQHR-RACHAGVLDPDDLQKALVIVACTA +DLDEQKQAGPVLESVGRAIR--- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=2 Tax=Sphingobacterium TaxID=28453 RepID=A0A653Z801_9SPHI +-kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE +KGELQLDQQLLYRASQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG +VAINKLMSDLQLAHTRVNSQTEGRKPDWERYGWGQTTPKEMADLVTLIRQGKVVSPKSSD +QMYRFMGNMFY-DERGLSQIPSTVKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN +NTGKTNEAEVLTRKLSKLLWDYy +>[subseq from] Uncharacterized protein n=1 Tax=Atopobium vaginae PB189-T1-4 TaxID=866774 RepID=E1L327_9ACTN +--ALKSELEQVVAPYGNAVSVSVVAIRTGATC-DINANKQVISASMIKLAVMAAYLQAVD +AGTINPQQALPLARIKIVGGTGKIQSERARTYTYDALCRYMIMYSDNTATNALIDDL-GV +DAVNSRARELGCTHTTLNRKLMQLNTG----VENYTSAADVSRLLCAFYTQTAASAGQCT +KAMDFLLQQTD-GDGIPQGLS-GVQFAHKTGTLS-GIRHDGGIVM--ERSPYTIVVMCEL +PEG---KANALMAQVARKTQQYf +>[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax sp. CF316 TaxID=1144317 RepID=J1E9U4_9BURK +------------------------------------------------------------ +-------------------------------------------------------PM-GP +QRVDALARTIEVDKADFRKTMDEAYRRYYARGLNSAPLTSYGGMLEKLVTGKLLSPAHQQ +RLFTDLKYATYDAYRLEAGLPRSERFIHKTGTQLH-RACHMGVVNPQDGGRAAIVVATCA +EDDEHGEAGKAFEQIGRAIT--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5P0DKN6_ECOLX +------------------------------------------------------------ +------------NKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQ----------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6LP02_9BACT +-----EELERLTAESKARAAVALHDLESGLRF-SLRGDRWFHAASTIKVAVLLAVFRAAD +EGRLRLDDSLHVRNRFISAGSPFRYQAIGRTAKISDLAQGMISASSNLATNLLLDFV-GV +EYARKVLQDAQVSGVELRRGVEDH-AAHERGINNEVTANGLLMLLSA-VRGDFLSNQSKE +QAIRILLEQRS-KSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EQEGRRETVAAISEVIYR-- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6M6V4_9BACT +--TLREALEKLARESKARVAVALLDLESGFRF-SLAGDRWFHAASTIKLAVLLAIFRAAD +EGRLRLDDSLHVRNHFVSAGSPFRYQAIGRTAKISALTEGMIVASSNLATNLLLDCL-GV +EYARNVLRDAQVSGVELRRGVEDQ-AAHEKGIDNEATADGLLTLLSAL-RGDFLKKESKE +QAIHVLLAQRF-NSMIPAGLPAHATVAHKTGEIST-ACHDVGIVYLPEREPYIAVILTEF +DA-EQNGRRETVAAISEVIYR-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=Q2FC40_STAHA +---HXKELNXLEKKYNAXIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTF--------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Pseudacidovorax sp. RU35E TaxID=1907403 RepID=UPI0009FB6570 +------------------------------------------------------------ +---------------------------------------------------------NGP +ARVEAIRRAVDAKRTDLATTMDEAYDRYYRRDLNTTTLIAYGGMLERLVRGQVLPDPPRA +VLYKAMKHDIYTGYRLQAGLPRDHAFIHKTGTQHR-RACHAGVLDPDDLQKALVIVACTA +DLDEQKQAGPVLESVGRAIR--- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5M2D0_9BACT +---LNEELETLSSESKARIAVALHDLESGLQF-SLHGDRWFHAASTIKVAVLLAIFRAAD +EGRLRLDDSLHVRNRFISAGSSFHYQAIGRTAKISALAEGMIASSSNLATNLLLDFV-GV +EYARNVLRDAQVDGVELRRGVEDYA-AHERGINNEVTADGLVRLLSAL-RGGFLSPQSKE +QAIGILLEQRF-NSMIPAGLPAHAAVAHKTGEIST-ACHDIGIVYLPEREPYVAVILTEF +DSE-GDGRREIVAAISEAIYR-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4Y5QBF7_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERIAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP +ASVTAFARQLGDETFRLDR----------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter salegens TaxID=143223 RepID=A0A1M7IZI2_9FLAO +-eKLQEKIDSIFKSIQGDFAIAFKDFSEEKDSiLINHHEDFHAASTMKTPVMIEVFKQSS +AGKFSLQDSLVVKNQSILDESYYSYEQIDQKRSIEDLVIDMIIYSSNLATNIIIELV-DA +ENVNKTMREIGAMNINVLRGVEDMK-AYEAGLSNSTTAYDLMLIFDALANGDAVNPEADE +EMLNILRQQKH-TDLIPHLLPKDLKIANKTGWIT-GVHHDSALVELPDGRKYVLVLLSKN +IE-DMDAGTKMLTEVSKMIYDH- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6GYL6_9BACT +--ALIEELERLTAESKTRAAVALHDLESGLRF-SLRGDRWFHAASTIKVAVLLAVFRAAD +EGRLRLDDSLHVRNRFISAGSPFRYQAIGRTAKISDLAEGMISASSNLATNLLLDFV-GV +EYARKVLQDAQVSGVELRRGVEDH-AAHERGINNEVTANGLLMLLSA-VRGDFLSNQSKE +QAIRILLEQRF-KSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EQEGRRETVAAISEVIYR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora inositola TaxID=47865 RepID=A0A1C5K381_9ACTN +------QLARVAAGTNNRAGVTVRDLSGHQQI-AVNGTFRPKAASVIKLWILVELLRRVD +CGQLSLDRGVLVTRADVVGGTGKLKFAIPQVVTIHRLTEYMIEYSDNTAANVLIDQLGGF +APVNALIDSMNQRETVLAHKFFD--DANDRGGENYTSPDDVISLLGAVWDAQILTESSRD +LMIDFMRKQTL-NTKIPAALPPRTPLAHKTGDLSD-VSHDVGYCLTPRA-EIAVAFLTAG +PFQS---GSETVRQLARTVHD-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Brugia malayi TaxID=6279 RepID=A0A4E9G452_BRUMA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGQAGTK-------------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Brugia malayi TaxID=6279 RepID=A0A5S6PD49_BRUMA +--ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP +KELTAFLHNMGQAGTK-------------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=8 Tax=Bacteroides TaxID=816 RepID=A0A6A2GHF0_BACUN +---LTDSISRIVSACPGEIGVAII-INNTDTV-KVNDKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVKIDRNRLDSWSPMMKDYSELVLTVRDLLRYTIAQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHDRAYFNYTSPLGAAMLMNRLFTESIVSGEKQS +FIKNTLKECVTGTDRIVAPLKERVSIAHKTGSGDNGAHNDVAYICLPNNVCYTLAIFVKD +FKGNESQASQYVAHISEVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7RH68_9BACT +-qDLAARIAARIAQTNQGVGVYYRRLDRPDSL-LVDARHRFHAASTMKVPVMIEVFRDAD +AGTLRLSDSLTVVNESIVDGSPYQYLRVGQKASVRDLLELMITVSSNLATDILIERV-GP +ARANATAHALGADSILVLRGVEDGV-AYRAGRNNTTTARDLGVLLAAIAEHRAASRVACD +SMLAILGRQHF-TEGIPAGLPPGARVYHKTGWVGQVVYHDAAYIEMPDGRRYVLVVTTGG +IQLD-TAAYHLVADVSRMIA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Arcticibacter pallidicorallinus TaxID=1259464 RepID=A0A2T0U601_9SPHI +---------------EAAFAVSYRDIDTGDKF-NINERESFHAASTMKTAVLAEVYKQAH +DGKFSLDDSILVQNSSIVDGSSFAYNLIGSHVSIRDILIRMVTRSSNLATNIIIEKI-GA +ENVNHTMRSLGAKDLRVLRGVEDIKA-FEQGLNNTTTANDLAVILEKIARNELINAQASE +EMIDILMNQYD-KNIIGGKLPLDVKVASKSGAITS-ICHDSGIVFLPDGRRYVVVLLSRG +ID-NHKAASQLLSNVSKHIYEY- +>[subseq from] Serine hydrolase n=1 Tax=Fictibacillus phosphorivorans TaxID=1221500 RepID=A0A5P0YF09_9BACI +-kQMERSLSDLLASGKGIYGCSLFDFKTKENF-TYHENESFYAASIIKVPIMAAVFAHAF +EGNYRLKDKVYIQDEDFVPGDGVLKHLSAGMWTIHDLLVLMIIESDNTATNVLIDLV-GK +ENVHAYMKEWGFKTSHLHHKLQISPDRIPG-EFNVITPHEINAFLILIATGRVVSIKACE +MMINILKQQKM-NDLLPRYLPASWEAAHKTGYVS-GVEHNVGLFYFPGHT-YAISVLSKN +VP-DRNEPREIMGQIGHLLF--- +>[subseq from] Beta-lactamase n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=A0A379BQU3_PEDPE +--TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN +EGKLNLNDKYTLKDSDKVNGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM +DKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN +AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD +GSRDEQ----------------- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000E369269 +------------------------------------------------------------ +------------------------------------------------------------ +------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRVELLSAESRD +LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE +GLDEGKEAGSLFEQVGQAIS--- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudorhodoferax soli TaxID=545864 RepID=A0A368XHV2_9BURK +-eRLTAALAHIDAAPDGRIGVYVRALGSGESA-SFQAEQSWYLASAVKVPVAVAVLRGIA +RGVYQLDTPVTLRADDYVDGAGSTNRAVGAALPIRYLLEQMVIHSDNTASDMLIGLV-GL +AQVNAVTAEVAPGGFGPITRLAEVRRAYYATGLNAGRLDAYGELLAQLADGQLLPPTQTR +YLLGLMERVVTGPQRIRAGLPAGARFAHKTGTQR-GRFCDAGIVQPAGGT-RVVVVACTR +GELSLVRAERALREVGTALC--- +>[subseq from] Serine hydrolase n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=A0A512K880_PEDPE +--TIQGTIDDAFGDMQGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN +EGKLNLNDKYTLKDSDKVNGTGIRNMSSGTEISIQDLLEEMMEDSDNTAANIVIRQLGGM +NKVNTQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN +AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD +GSRDEQ----------------- +>[subseq from] serine hydrolase n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI00049384CF +--TIQGTIDDAFGDMQGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN +EGKLNLNDKYTLKDSDKVNGTGIRNMSSGTEISIQDLLEEMMEDSDNTAANIVIRQLGGM +NKVNTQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN +AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD +GSRDEQ----------------- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. CRM56-3 TaxID=2678357 RepID=UPI0012D3CE69 +---AQRQIRTIEQRTSGRTSVYVRNLQTKRPVvMH--NRQQRSASVIKLFIMIAVFRQIK +LGRLSASQMVTIPKQDRVGGTGVLASQSTKQLSVNQLLTLMIRNSDNTATNVLIDQLGGL +RPVNTEIQRLGCTQTVLQRKMLDYQ-ALKNGKDNLTSVADVGHVLGKLYQHQILGNPYDA +QMLQLLRHNAN-QSKIPTLINQKAIIYNKTGEFDYGVQNDAAIVKKGHQA-FVAVVLSEN +GAQ--NRQIKAMQQLGR------ +>[subseq from] CfxA family class A extended-spectrum beta-lactamase n=1 Tax=Porphyromonadaceae bacterium TaxID=2049046 RepID=A0A3B8QYE7_9PORP +--SLRDELYALVDTVPGTVGIAFIC--DNDTA-TVNNGVKYPMMSVFKFHQALGVAETVE +KRWNTLDSMLLVHSNELDRWSPMLKKYPEGDISISELLSYAITKSDNNASNLMFKHILSP +GETNDFVKSIRDTTFQIRYSESEMKAKHPLSYLNCTSPLAAASLMRQVFEEQLVDAAAQD +SIRHYLSIVTTGHDRLGAAVEDIMIFAHKTGSGYRNAHNDVGYFRLKDGRSYSLAVFIRD +FRGSEEEASAVIANISKCVYNRf +>[subseq from] Uncharacterized protein n=2 Tax=Candidatus Entotheonella TaxID=93171 RepID=W4LS93_9BACT +------------NEAHGSIGVSAIS-PCGERW-EVQGKTRFPAASTVKIPIMIEIYRGID +RGELAIDDTYIVRSADKAPGSGVLQHHAGLQLSLGDLLYLMMSISDNTATNILIDMA-GM +DRINATMQDLGMAASTLGRPMRGRL-AIEGEEENWATPNDYTAVVKALIDEQAASPAACQ +AMLTTLTLQQN-HRRIGRYVPKSYRWGSKTGSNT-GITNDVGFVQSPAGT-MIIALYSQG +IG-DAVTSEIALSDIAEAAMQ-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia asiatica TaxID=209252 RepID=UPI0002F09BA8 +-------IRAVFADAGCSGWLHARRCDSATEI-SVGGAERVVLASVYKLPLFVAFCRLVD +AGRLDPATRLTVTPSDCTPPTGIAVMRDPVTMSLRDLATSMMTVSDNAAADVLLGAT-GL +GAVEDLLNDLGLTHTRIVGGTADLHRAYDPSYTSATTPEEMTRLLRALWSGAVLSDEQTE +FVRTVMRHQVW-PHRVTAGFPRSVSVAGKTGTIGV-IRNEVAVVEFPGEHPVAVAIFTRA +ARADLPVVDAAIAEAARIAVT-- +>[subseq from] Beta-lactamase TEM-12 n=2 Tax=Bacteria TaxID=2 RepID=A0A2H5WMU3_9BACT +--KLKARLDAICEKFRGVMGYSLFHKRYQHRI-HRLGDEIFPTASTIKVAVMSKAFEEID +AGRLSYNEKLPITPDDIRDGSGLLQFFKENQVEVRMLIHLMITVSDNTATIMLARRL-GT +VEVNKHLQRLGLKDTRLLALHPELKAYREKWGMGMCTPNEMVALLDAILTNRAGTPAACE +RMIRIMAHQYY-DDLIGSSVPPWVVCATKSGAISR-SRSDVGIVFAPSGT-YILAVYTKE +AETPDNEGEVAIRAVAHEVWKFy +>[subseq from] serine hydrolase n=1 Tax=Clostridium bornimense TaxID=1216932 RepID=UPI0006888D76 +---------------TSNYSLAFKDLSQKSTL-SINSEKT-ISASTIKIYIMIETFNQIK +SGNINLDDTVILEESMKTDGSGMLSSKATGEFTINELITLMMIKSDNTAANILIDKI-GM +ESINNCIKNLGCKDTELNRKMMDAT-AIEKGVENYTSVDDLCLTLEKLYNKQCIDEYYDN +LMLDIMKKNEN-HTKIPKLLPDTLSIANKSGEYT-GVENDAAIITTDKGA-YVLCITTSN +GGS--GSQIKTINNISKDIYNKf +>[subseq from] Beta-lactamase n=1 Tax=Clostridium hathewayi CAG:224 TaxID=1263067 RepID=R5TCG1_9CLOT +------NVTDQIKGLPGKTGFYYENLVTGERA-AYHEEERMMAASVIKLFVMTEAFTRFE +EGTLSPDRIIRMRREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTATNVLIDLL-GI +EEINRTIRRLGYRDTVLRRKMYDTEKS-KQGIQNYITAAETGRLLREMYQGRLVSRTASE +AMISILKNQQL-CSKIPQALPEEPEIAHKTGEDC-GITHDVGIIYAKQ--P-FIVCYCGN +DT-DTPAYERVMAETALWLY--- +>[subseq from] serine hydrolase n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI0003C3376C +--TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN +EGKLNLNDKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM +NKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN +AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD +GSRDEQ----------------- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI001008EB5D +--TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN +EGKLNLNDKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM +NKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN +AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD +GSRDEQ----------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Thermoflavimicrobium dichotomicum TaxID=46223 RepID=A0A1I3UDI7_9BACL +-qKLEEKIGQLLEAFSGKAGVAVE-TEEGW-I-GFHENEPFLAASLIKVPIMIETYRQVQ +EGRLSLSQLYQIPEKKRVGGSGVLSSLREQVVSLQDLISLMIMVSDNTATNLLIEQV-GF +DAVNQLASKLKCDQTLLGRKLMDYAAK-RRGLENFTSAGDMVRFFKEIMEGSLLNETYKN +CALDVLKKQQF-QAKLPGHLEGHDFIAHKTGEMRD-YEHDAGILSVNGK-IAYVAVLTSH +GT-DAFSRRNLIADVGKALFDY- +>[subseq from] Uncharacterized protein n=1 Tax=Bdellovibrio bacteriovorus TaxID=959 RepID=A0A150WBR7_BDEBC +-kNFEESLKELESKQPIQLGVFVKNLSTGEVL-SYRGEDLWYVASGVKLPIVLENLRQVD +QKKYTLNSQIELRKEDFVDGAGYTNYKKAGSLSVKFLVEQALIYSDNTASDLLIRQA-GL +DSVNSCIQDLVPGGFTAITTLADVRRNYYSKKLNSATLKAYAELLEKVAEGKILGDSTQK +FLIETMTKVQTGPHRIKAGLPKKYSFAHKTGTQHS-RICDFGIAWDKKSTGVVIAACVKD +FK-SLDVAESALKSVGVA----- +>[subseq from] Beta-lactamase n=2 Tax=Micromonospora lupini TaxID=285679 RepID=I0KXC6_9ACTN +---------------------------GDQQI-SVNGALRPKAASVIKLWILVELLRRVD +CGQVSLDDGVLVTPADVVGGTGQLQFETPQVVTLYRLARYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGTVWDGEILTPDSRD +LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2E0F9M0_9BACT +---LENKISNLIKSHKGTFAVALKSLDDGNTI-LINENEIFHAASTMKTPVMIELFKKKH +NGEVSFEDSLQIKNESIVDGSKFEYKKLGKYISIRELVSAMITKSSNLSTNLLIDYI-NV +KNVNKTMRDMGAENINVLRGVGDLKA-FDKGLNNTTSAKDLLVIYEKLAMGLFINPSISN +EMVEILKNQVY-KDIIPKYLPDNIEVAHKTGWIS-GVRHDSGIVFLENGKKYVLILLSKN +LDD-DIEGAEFLAKISLEIFN-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. CZ-UAM TaxID=1933868 RepID=A0A1V3MWC2_9SPHI +-kKLEKQIKQLIQGFQGEVGIYVHDLKKHKEV-NIGADSIFPTASVVKIPILVGVFDKIE +KGQLQLDQEYIYRESQKYGGSGLMQFFKDSSVDLKTLIALMLSYSDNVTSIWNQKLAGGG +IAINRLMADLQLTHTRVNSQTEGRKADWEKYGWGQTTPKEMADLLTLIRQGKVVSAKSAD +RMYRFLGNMFY-DERGLSQIPATVKSASKTGSLDD-VRNEVILVNASKGD-YVFSIFTKN +NQGKTNAAEVLTRDLSKLLWDYf +>[subseq from] Putative membrane protein n=1 Tax=Clostridium bornimense TaxID=1216932 RepID=W6S7R4_9CLOT +---------------TSNYSLAFKDLSQKSTL-SINSEKT-ISASTIKIYIMIETFNQIK +SGNINLDDTVILEESMKTDGSGMLSSKATGEFTINELITLMMIKSDNTAANILIDKI-GM +ESINNCIKNLGCKDTELNRKMMDAT-AIEKGVENYTSVDDLCLTLEKLYNKQCIDEYYDN +LMLDIMKKNEN-HTKIPKLLPDTLSIANKSGEYT-GVENDAAIITTDKGA-YVLCITTSN +GGS--GSQIKTINNISKDIYNKf +>[subseq from] serine hydrolase n=1 Tax=Clostridium lundense TaxID=319475 RepID=UPI0005560C11 +-----DKVKEEIDGFKGTCGVIIKNENTGDCL-QYNEDVVFPAASIIKLSILLELFKKVD +NGDINLQERVVLKESEKVDGFGVLKELDCDVLTIKDLATLMIILSDNVATNKLIHIL-DM +ESINNTIKELGMKDTVLGRKMMDGEA-KKKGLDNYTSAKDTLIMLEAYLNYSKLSAKNRE +TILDILKKQQC-NNKLPLLMPKDISFGHKTGDLP-GVEHDAGIIFSKIGQ-IIIIVLTKD +LEK-NTYGVQLNNNIGKIVAEY- +>[subseq from] serine hydrolase n=1 Tax=Bdellovibrio bacteriovorus TaxID=959 RepID=UPI0012DA7FD6 +-kNFEESLKELESKQPIQLGVFVKNLSTGEVL-SYRGEDLWYVASGVKLPIVLENLRQVD +QKKYTLNSQIELRKEDFVDGAGYTNYKKAGSLSVKFLVEQALIYSDNTASDLLIRQA-GL +DSVNSCIQDLVPGGFTAITTLADVRRNYYSKKLNSATLKAYAELLEKVAEGKILGDSTQK +FLIETMTKVQTGPHRIKAGLPKKYSFAHKTGTQHS-RICDFGIAWDKKSTGVVIAACVKD +FK-SLDVAESALKSVGVA----- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522RA87_9BACT +------ILAEFAKQPTGTFAVAFKDISTGEIF-LMNAHESFHAASTMKTAILIETFKQAT +GHKFSLTDSILIKNSSIVDGSPFSYTRIGTKLPVNDLLYRMITESSNLATDLIVDLV-GA +ENANKTMHELGAKDIKVLRGVED-NKAYDLGLNNTVTAYDLMVIFDHIADGTVVNKKACD +AMIKILMHQHF-REKIPALLPADVRTATKSGSIDK-ISHDSGIVFLPDGRKYVVVLLSRG +IE-DEKSADETLARISRIIYNY- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7P8Z1_9BACT +--ALAQRLAERIARAPARVGLYYRSLAGSDSL-LIGANLRFHAASTMKVPVMIQIFRDAD +AGLLRLDDSLTVHTASLVPAEAFIYESVGRNRSVRELLELMITRSSNLATNILIERV-GA +VRAQASARALGAWSIQVLRGVEDGQ-AYRAGLNNTTTARDLGVLLIAIVQGRAASRPSCD +SMLAILGRQEF-NEGIPVGVPPGTRVAHKTGWIGEVVYHDAAVVYPARGGPYVLTVLTGG +IKED-SVAHNLVADLSRLVY--- +>[subseq from] Beta-lactamase n=1 Tax=Sporomusa acidovorans DSM 3132 TaxID=1123286 RepID=A0A259V193_9FIRM +---LSEQVKNFSTQKEAKYAIYVRPLGEKGHD-VVLNSHKMASASLIKIPIMIEAFNQKN +QGKLDFNEQVTIRRAETVEGGSVYNLADGTVLTIAQLVELMIVQSDNSACNILIDKL-KM +DNVNAMIKKLGCSDTSLQRKMMDFAA-VKQGRQNYTNVTDMANILEKLYYGKCLDPKSDK +AMLEIMARQED-NTIIPAQLPHHIKIAHKTGELD-GMNYDCGIVYGQSRT-YILCMMAEN +VK-DE------------------ +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. Marseille-P299 TaxID=1805477 RepID=UPI00082CDF49 +--------------VEGKVGFYYKNLITGEII-TYQHEEAFEAASVIKIPILIEVYRKIM +DGSLHENQIFQVKEDDKLPCGALTYMHTGLEVTLKDLCTLMIILSDNTATNMLIKLV-GM +DQINETMRGLGLKKTKVNRLLFDSKQS-ALGIQNYITSGEIGILLEKMYDGSLISKEASK +EMISILMNQRL-NGKIPFYITDGTKVAHKTGEDS-GITHDVGIVFTK--EPFIVCFCSNN +VE--VPYFERVIQEISRD----- +>[subseq from] serine hydrolase n=1 Tax=Fictibacillus phosphorivorans TaxID=1221500 RepID=UPI0011A9CDEB +-kQIEHSLSELFSSGKAMYGCSLYDFRTKESF-THYENETFYAASIIKVPIMAAVFAHAF +EGKCRLQDKVQIQEEDFVPGDGILKYLSAGMWTIYDLLVLMIIESDNTATNILIDLI-GL +ENISAHMSGWGLKKSQLKHKLQISPDR-KPSELNVITPNEINQFLTQLALGRVVSIKACD +MMIKILKQQKM-NDLLPSLLPPNWEAAHKTGDVS-GVEHNVGLFYFPGHT-YAISVLSKN +VPH-RTEPRRIMGEIGQLLF--- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5L796_9BACT +--TLNEQLERLTGQSKAQIAVAVHDLESGLRF-SLEGDRWFHAASTIKVAVLLALFRAAD +EGRVRLDDSLHVRNRFISAASSFHYQAIGRTAKISALAEGMIAVSSNLATNLLLDLV-GV +EYARKVLRDAQVEGVELRRGVED-HAAHERRINNEATANGLLTLLSAL-RGDFLSSESKE +QAIRILLEQRF-NSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DL-EQNGRRETVAAISEAIYR-- +>[subseq from] Serine hydrolase n=1 Tax=Ferruginibacter sp. BO-59 TaxID=2294116 RepID=A0A3M9N2V2_9BACT +-----EILAEFAKQPAGTFAVAFEDLATGEQF-LMNAHENFHAASTIKTAFLIETFKQAD +EGKFSLNDSILIHNDSIVDESLYHYRRIGQKETIYNLLYRMITQSSNFATNLIVDLI-DA +KNANSTMRSIGAKNIQALRGVEDSK-AYELGLNNTVTAYDLMIIFDHLDKGTVVNKPACD +SMIQILMHQQL-REKIPAKLPANVKVANKTGSITK-ISHDSGIVFLPDGRKYVLVLLSKG +VE-DENAANETLARVSRIIYDY- +>[subseq from] CDP-alcohol phosphatidyltransferase n=1 Tax=Prevotella sp. khp7 TaxID=1761885 RepID=A0A1I0QQN8_9BACT +--------------------------RDGSVS-GVNQNERFAMHSVMKFPQALYVADYLG +RKGLALDDTIVVDKADLMQWSPMLKRFEGKGISYAELLELSLGQSDNNACELLFKYCGKP +KIVEKYMRKLGCRDIHVRMTEEQMHKNPAKAIENSSTPAEMVRLFEWFYHHKD-NNQYLT +FIWKAMADCSTGLKRIPAAIPAGARIVHKTGTGFVQDMNDAGIILMPDGSYAIIAVFTTH +SP-----SEAVIENIAKQLL--- +>[subseq from] serine hydrolase n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=UPI000E0C3701 +------------------------------------------------------------ +--------------------------------------------------------RNGP +ARVEAIRRAADVKRTDLATTMDEAYDRYYRRDLNTTTLIAYGAMLERLVRGQVLPDAPRA +LLYKAMKHDIYTGYRLQAGLPRDHAFIHKTGTQHR-RACHAGVLDPDDLQKALVIVACTA +DLDEQKQAGPVLESVGRAI---- +>[subseq from] serine hydrolase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013BCA4EC +--GVADRIRAVFADAGCTGWLHARRCGTTAEI-AVDGRDRVVTASVYKLVLFVAFCRRID +DGLIDPGARITVHPADCTPPTGIAALHDPVTMSHRDLATSMMTVSDNAAADILLGEI-GL +GAVEELLAELGLTETRIVGGTADVHRAYDPSYASATTPEDMTRLLQLVWGGGVLSPEQTG +FVRAVMRKQVW-PHRIASAFPRGVFVAGKTGTIGV-IRNEVAVVEFPGEYPIAVAVFTRA +ARADLAVVDAAIAEAARIAVT-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=Q2FC70_STAHA +---HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTF--------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5SC08_9BACT +---LHEELEALALKNKARIGVALHDLETGFRF-SLRGDRWFHAASTIKVAVLLAVFRAAD +EGRLRLDDSLHVRNRFFSAADGSLYAAIGRTTKISALAHAMICGSSNLAANLLLDFV-GV +EYARTVLREAQVDGVELRRGVEDH-GAHERAINNEATADGLLSLLSAI-RGDFLTPESKR +EVIRILLEQRF-NSMIPAGLPPHATVAHKTGEIST-ACHDIGIVYLPEREPYIAAILTEF +DS-EREGRRETVAAISEAIYR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptosporangium subroseum TaxID=106412 RepID=A0A239NPD8_9ACTN +------AIEGLFRTAGVTGSLHVMDIDTGAEV-AYDADGSVVVASVFKVALLVELFRQAD +RGVLDPAERVTVMADRHTAGSTGVSVMADDVMSLRDLAYLMIAVSDNTAADAVIDRV-GL +PAVNTMLAAFGLDRTWIEHDCRELFSALDPARTNRSTPRDMTRLLSMIWRDEAASPESCA +SMRRLLGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-IRNEIGVVEYPDGGRYAVAVFTRS +TAQNQPRADAVIGTAARAAVE-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides eggerthii TaxID=28111 RepID=UPI000E4C0C05 +----TDTISKIVAYYPGEIGVAVI-INNTDTI-TVNNKSIYPMMSVFKVHQALAICDDFG +HKGFSLDSLMTIHRDELDPWSPIMKEHLEPVLRVKDLLCYTLILSDNNASNFMFKKLVNI +TQTDSFIATIPRLSFQIAYTEEEMSADHDKAYANYTSPLGAAILMNRLFTDSLIDYDKQQ +FIIKTLEQCSTGKDRIAAPLKDGITIAHKTGSGYTNAHNDVAYIRLPNGICYTLAVFVKD +FKGNETQAAKAIAHISAIVYS-- +>[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00132FED40 +------------------------------------------------------VLKQSE +TQKQLLNQPVEIKPADLVNYNPSAEKHVNGTRTLAELSAAALQYSDNTAMNKMMAQLGGP +GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA +QLVTWLKGNT-------------------------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Sporosarcina koreensis TaxID=334735 RepID=UPI00075E296F +-kTLQEKIESRLKDAKGIWSVSVEDLNEGTSF-SLNGNELFYAASIIKVPIMAAVFAVAE +EGNIRLGDRLLLRRDDIVGGSGVLQFMSPGILPIYDLLTLMIIQSDNTATNMLMDLI-GM +EKIQAVMNGLGMERSEIHHKLMIAQTN--RVNSNEITATDVNALLTRIVRGECVSLHASE +QMIRIMKQQQLSNGLIDS-LPPDWEFAGKGGSVE-GILHECAILYARGR-CIAVTVLSKG +CSED--EARKTIAQIGSEVY--- +>[subseq from] Uncharacterized protein n=1 Tax=Sphingomonadales bacterium 28-55-16 TaxID=1970589 RepID=A0A258RWT6_9SPHN +--KLKSEIDGYWKKFPGRAGIAIYTPFSDEII-GKRQTERFPQQSVSKMWVALTILEQEA +AGKLSLDKRIRITPDDVVVFSQPLKRYLDGKMPVRELLAHAINASDNLANSVLLRVAGGP +EAINQMLDRRKVQSIRFGPGEVLLQSAYLKAPLDGAAPGTIVLALKRFSERG--PNDPGA +KLLKIMAGTYTGRSRLRSGLAPHWSLAHKTGTGQSTALNDVGVMKAPDGCLYPVAVMIAE +TRSGKEVSNGLMQNVARAVIRH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC80_STAAU +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTF--------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides eggerthii TaxID=28111 RepID=A0A415RUU1_9BACE +----TDTISKIVAYYPGEIGVAVI-INNTDTI-TVNNKSIYPMMSVFKVHQALAICDDFG +HKGFSLDSLMTIHRDELDPWSPIMKEHLEPVLRVKDLLCYTLILSDNNASNFMFKKLVNI +TQTDSFIATIPRLSFQIAYTEEEMSADHDKAYANYTSPLGAAILMNRLFTDSLIDYDKQQ +FIIKTLEQCSTGKDRIAAPLKDGITIAHKTGSGYTNAHNDVAYIRLPNGICYTLAVFVKD +FKGNETQAAKAIAHISAIVYS-- +>[subseq from] Extended-spectrum beta-lactamaseR-1 n=1 Tax=Symbiodinium microadriaticum TaxID=2951 RepID=A0A1Q9CUT2_SYMMI +-------------------------------------ERRFPMASTFKIPLALSVLQMVD +AGRFSLEQKFVLDAFDVRPGTGVLRDEIRTECSLYELLEKALNDSDNTATDVLLDRVGGP +SVVFEHLKKLGLDEIRVARSCLEHLREFDADLRDTTTPEAMAGLLEKIWNREAISDGSTQ +VLLEIMGHCRTGAKRILGRLPRYPRVQHKTGSLG-GRANDVGIVYLPNGHAFAICCYTKG +LAQSYEERERLIADVARACYD-- +>[subseq from] serine hydrolase n=1 Tax=Pseudorhodoferax soli TaxID=545864 RepID=UPI000DF1273A +-eRLTAALAHIDAAPDGRIGVYVRALGSGESA-SFQAEQSWYLASAVKVPVAVAVLRGIA +RGVYQLDTPVTLRADDYVDGAGSTNRAVGAALPIRYLLEQMVIHSDNTASDMLIGLV-GL +AQVNAVTAEVAPGGFGPITRLAEVRRAYYATGLNAGRLDAYGELLAQLADGQLLPPTQTR +YLLGLMERVVTGPQRIRAGLPAGARFAHKTGTQR-GRFCDAGIVQPAGGT-RVVVVACTR +GELSLVRAERALREVGTALC--- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5NEJ6_9BACT +--ALIEELERLTAESKARAAVALHDLESGLRF-SLRGDRWFHAASTIKVAVLLAVFRAAD +EGRLRLDDSLHVRNRFISAGSPFRYQAIGRTAKISDLAQGMISASSNLATNLLLDFV-GV +EYARKVLQDAQASGVELRRGVEDH-AAHERGINNDVTANGLLMLLSA-VRGDFLSNQSKE +QAIRILLEQRS-KSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EQEGRRETVAAISEVIYR-- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=A0A5E8KG21_BACFG +---LTDSISRIVSACPGEIGVAII-INNTDTV-KVNDKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVKIDRNRLDSWSPMMKDYSELVLTVRDLLRYTIAQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHDRAYFNYTSPLGAAMLMNRLFTESIVSGEKQS +FIKNTLKECVTGTDRIVAPLKERVSIAHKTGSGNNGAHNDVAYICLPNNVCYTLAIFVKD +FKGNESQASQYVAHISEVVYS-- +>[subseq from] Beta-lactamase n=1 Tax=Limnochorda pilosa TaxID=1555112 RepID=A0A0K2SP07_9FIRM +---IYDELTELDAGFSGTLAVAARGLSRRPAL-SFRAAETFPAASVIKLPILVEAFRQAE +EGRLDLARRVPLRTEDQVGGSGVLKELEPGLPTLRDLLTLMIVVSDNTATNMVMERV-GI +EAVNASAQAWGLRQTYLAGPLLAPPEAQREGRRSTVSPADMVELLTALHRHQILSEAGCE +QVLEILGRQHF--SVLGRELGSDLRIQSKSGSIA-GVRNDVGIISTSHGA-YAVAVMTKD +SRAYQNEGETVVARASRLVFDHw +>[subseq from] serine hydrolase n=1 Tax=Nocardia jinanensis TaxID=382504 RepID=UPI0007386253 +----ADRIRAVFADAGCTGRLHARRCDGGDGQvSIGGTERVVTASVYKLPLLLAYCRAVD +SGRLDPLSRLTLTPSECTPPTGISALHDPVTMSRRDLATSMMTVSDNAAADLLLGEV-GV +GTVHELLESLGLDHTRLVGGTADIQRAYDPAYTSATTPEEMTRLLSALWRGQVVSQEQTD +FACSIMRRQVW-PHRIAAGFPRGVAVAGKTGTIGI-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLPAVDAAIAEAARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Halomonas titanicae TaxID=664683 RepID=A0A558JFU3_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +----ALARALGVTDTFTQPDYDHAFDAYEATGENVGTLSAFGDLLASLHHGRALDAEQRQ +TLLALMQRTRSGKQRLKAGLGSGISFAHKTGTQQR-RSCDAGIAESDTEGPWVIVSCTRG +PLA-VSAHERALASVGEA----- +>[subseq from] Beta-lactamase n=2 Tax=Clostridium TaxID=1485 RepID=Q97MK6_CLOAB +---LKKTIENLITSNKEDISLVFLDLKKPSNHiYIKENEVFPSASTIKVLIMAEALNEVL +SGNHALEEKIEIKSSDKVNYSIVTC-LTNKIYPLIDLLTLMIISSDNTASNILIDLL-TM +DSINNYGKKIGLKTTLLRRKMMDSNAA-KEGRENITTAFDMLTLFSKIYNKKILSPDMCD +LMLKILSNNTD-CEVLLRYLCDDIRCAHKTGDLPH-LNHDIGIFRTENA-EYILGVFVRS +VQFN-YEAKDTIGKISKEIH--- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas sp. PA1(2017) TaxID=1932113 RepID=UPI0009FB6293 +------------------------------------------------------------ +----------------------------------------------------------GP +QRVEAVANALEMKPDQLERDLDEAYRRYYETGLNSATLVAYGQLFGKLAKGELLSEASTR +ALYDIMGLDSYEAYRLEAGLSEQVPFVQKTGTQQH-RACHMGIANPQGDDALVILACAEA +LDED-AEAGKLFEEVGEAI---- +>[subseq from] serine hydrolase n=1 Tax=Cyclobacterium marinum TaxID=104 RepID=UPI0011EFC87A +--SAQQSLKAYLKTIDNKVSLYIIQNKQGKILsMSNSDKIIPSASIIKVPLLIYFMQKAS +EGTFSLQDHYHLKVEDKVGGSGELQFKPAGIVTYEYLAKEMIRVSDNTATNIIIKKL-GL +KAFQKWMKENDYSATQLNRFMMDFD-AIEKGKQNYCSSKEINRLLLALYNGNLLAENPSL +KVIEWLKNCED-NTGLPHLLPDRVAIAHKTGTLDY-VRGDAGIIFG--EKPIFITVLVEN +FS-EIAEADSIISTIGRLAYLEy +>[subseq from] Beta-lactamase n=1 Tax=Halomonas campaniensis TaxID=213554 RepID=A0A2D0AXX3_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +----ALARALGVNDTFTQPDYDHAFDAYEATGENVGTLRAYGDLLASLQQGRALDAEQRQ +ALLEIMQRTSSGKQRLKAGLGSGISFAHKTGTQQR-RSCDAGIAERGNAGPWVIVSCTRG +PVA-VSAHERALTSVGEA----- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus nitrificans TaxID=651560 RepID=A0A3M8CTW8_9BACL +---LREKVTQLLDKAEGSWGVVVEDLDRGQCF-AHRREEAFIAESVMKVPIMAAVYAAAA +QGEFQLDDRISMRAEDQVGGSGILFALSPGLLTIREWVTLMIIQSDNTATNVLIDLV-GK +QRIEQTLIELGMERSKYSRKLMIYPVG--VTENNMITAGDVSRMLGAIATGRFLSHRACE +EMVAIMKRQQV-LNGLPSLLPPDWEIACKSGWDS-GRQHDVGVFYTEGR-RFSIVALSQD +VQ--SQSALRVLGQIGKEVYEY- +>[subseq from] Uncharacterized protein n=1 Tax=Collinsella sp. 4_8_47FAA TaxID=742722 RepID=A0A096KQ88_9ACTN +--AIQQDIEALAEPYSGSTSVYAVALDLDGEV-AVAPDARRVAASIIKLPILACALEAVT +AGELSLDEQITVTQQDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANLVIGRL-GM +DTVNETCAALGLTQTVLARLMMDAEAQ-AQGHENYTSARDAAVVLQRLAAGTIATPELCE +RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD +LEREQ------------------ +>[subseq from] Beta-lactamase class A n=1 Tax=Propionispira arboris TaxID=84035 RepID=A0A1H7B0V3_9FIRM +---LSKQVSTIPIEKDVKYAVYIKNLKVDDKA-VVLNSHKMASASLIKIPIMIEAFNQKN +QGKLNFNEQIVIKHAQAVEGGSVYNLPDGTVLTVGQILDLMIVQSDNTAANILIDKL-KM +ENINAMIQKLGCKDTILQRKMMDFEA-VKQGRQNYTSVTDMANILGKLYNSQCLDPESDK +AMLAIMLQQED-NTVIPAQIPHDLKIAHKTGELD-GMYYDCGIIYGHSSD-YILCIMAEN +VKD-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus deserti TaxID=673318 RepID=A0A2N5M2G8_9BACI +---LEELLKAHLTLTSGRISLALEI--QGEKF-EYNSRTIIPSASLIKLPILIAAYRESE +KGKLFLHRRVTVTREDKTGGSGVIQSLSEGLFTIKDLLTLMITVSDNTATNVCIDLI-GL +DSINDTIKEIGLRHTVLGRKMMDWDG-IKEGKNNYTSANDMLLCMKAINEQGILTEESRT +DILNILQSQQF-VDKLPAHMDTDITIANKTGELP-GAEHDTAIIKFKEKT-AYAAVLTDG +L-LSQEEGRQAIRNIGHIIYNH- +>[subseq from] serine hydrolase n=1 Tax=Collinsella sp. 4_8_47FAA TaxID=742722 RepID=UPI000A06A52B +--AIQQDIEALAEPYSGSTSVYAVALDLDGEV-AVAPDARRVAASIIKLPILACALEAVT +AGELSLDEQITVTQQDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANLVIGRL-GM +DTVNETCAALGLTQTVLARLMMDAEAQ-AQGHENYTSARDAAVVLQRLAAGTIATPELCE +RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD +LEREQ------------------ +>[subseq from] Serine hydrolase n=1 Tax=Lactobacillus murinus TaxID=1622 RepID=A0A4S2ENP7_9LACO +------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK +IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI +DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA +EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENENGA-FVVVVLTQN +GDNNEEQ--AA------------ +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus murinus TaxID=1622 RepID=UPI00138F47A7 +------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK +IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI +DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA +EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENENGA-FVVVVLTQN +GDNNEEQ--AA------------ +>[subseq from] Serine hydrolase n=1 Tax=Balneolaceae bacterium TaxID=2053516 RepID=A0A6C1NXP4_9BACT +---------------NALFSVAVHDADGAELY-ARNAGRQVASASVIKIPILAELMRMVD +GNELSLDETYTMTSGDIVGGSGELQHAGPGGYTLEYLAREMIRVSDNTATNIIIRRI-GM +ERINRLMAELDMDQTVLARYMMDFQ-AIEEGRQNYTSAADMNRVLLAIMG---------- +------------------------------------------------------------ +----------------------- +>[subseq from] HGE-1 beta-lactamase n=1 Tax=Azospirillum sp. CAG:260 TaxID=1262706 RepID=R6I2E7_9PROT +-------------GSGSRVGIAVLS---GDKV-LTVGKGAMPLMSVFKMFVALNVLEHQE +-----KDKVLIVTEEMINRYSPMLKDYPVVPISVAELLKYMVSASDNNATDILLAFGGDI +RATQDYVRGLGFPGIVLKVNEQEMHENIRNQYLNRAVPADVVKLLRIVRESERLTNENKR +FFEALMTETATGADKIKKYLPSNVVVGHKTGSSDNGADNDVGFVRLPDGREYYLGVMIAD +SPMSDRDNAELIARISKIVYRHf +>[subseq from] Serine hydrolase n=1 Tax=Halomonas sp. TaxID=1486246 RepID=A0A2G2L6B6_HALSX +------------------------------------------------------------ +------------------------------------------------------------ +----ALARALGVNDTFTQPDYDHAFDAYEATGENVGTLRAYGDLLASLQQGRALDAEQRQ +TLLDVMERTSSGKQRLKAGLGSSISFAHKTGTQQR-RSCDAGIAERDNAGPWVIVSCTRG +PAA-VSAHERALTRVGEA----- +>[subseq from] Beta-lactamase class A n=1 Tax=Laceyella sediminis TaxID=573074 RepID=A0A2T0YJD6_9BACL +---LIQNLEHWKGRAVGNWGVWIEDLTSATTW-AWNETKSFYAASIIKVPIMVAVYKQAF +LGRLALADEIILTAEDQVGGTGVLQHLSPGLLSVQDLTTLMIIQSDNTATNILIDLL-GT +ETIRETMDELGMRQSTFYNKLMIVPAEPA--GLNMITAADVARCFRHIAQGKAVSQHASR +QMVEILKKQQL-RDCFPTGLPSQWELAHKTGMVTR-TLHDAGILFTKSRA-VVMVALSEE +CE--YEQAQQQMKQLARLVYE-- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI0006D8A9C8 +--TIQGTIDDAFGDMQGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN +EGKLNLNDKYTLKDSDKVNGTGIRNMSSGTEISIQDLLEDMMEDSDNTAANIVIRQLGGM +NKVNTQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN +AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD +GSRDEQ----------------- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora violae TaxID=1278207 RepID=UPI00102BD6FB +-------------------GATVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQAFLDDGVLVTPQDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWNAEILTPASRD +LMIQFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. CAG:1031 TaxID=1262917 RepID=R5AQ20_9BACT +-aELKKELTAIADSAKGDVGIALIY--DGDTL-TVNNDAIYPMMSVFKLHQAVALCRMFE +ENGTSLDSVMTLRRSELDPWSPMLKDHSDEELPMRRLLEYTLIESDNNASNEMFVRLMPP +AACDSVIAGIPRGSFEIRFNEAEMQADHSRAYSNRTSPLGAAILIDRVFTDTLVGKSYQD +FIKSALMRCQTGPDKISAALSEGITIGHKTGSGYRDASNDVAFISLPDRRHYALAVFVKD +FDGTDAEAAATIARISAAVIK-- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5UAI2_9BACT +---LTEQVERLTAESKARTAVSLHDLESGLRF-SLRGDRWFHAASTIKVAVLLALFRAVD +EGRVRLDDSLHVRNRFFSAGSPFQYQAIGRTAKISALAAGMITASSNLATNLLLDFL-GV +AYARNVLRDAQVQGVELRRGVEDH-AAHEKGINNEATADGLVTLLSAL-RGDFLRSESKE +RAIRILLEQRF-NSMIPAGLPPHAAVAHKTGEIST-ACHDMGIIYLPEREPYIAVILTEF +DS-EKEGRRETVAAISEAIYH-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. 1001175st1 A10 TaxID=2559709 RepID=UPI001106006A +------NVTDQIKALPGKTGFYYENLVTGERA-AYHEEERMMAASVIKLFVMTEAFTRFE +EGTLSPDRIIRMRREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTATNVLIDLL-GI +EEINRTIRRLGYRDTVLRRKMYDTEKS-KQGIQNYITAAETGRLLREMYQGRLVSRMASE +AMISILKNQQL-CSKIPQALPEEPEIAHKTGEDC-GITHDVGIIYAKQ--P-FIVCYCGN +DT-DTPAYERVMAETALWLY--- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI0013034B8B +--TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILIIAYQQVN +EGKLNLNDKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM +DKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN +AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD +GSRDEQ----------------- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI0007C563BB +-eRLQERLEPLLTQESARISMAVYATDGTSLF-EWHAQRVMPSASLIKTPMLLCLLEQVA +QGKLSLDTVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM +DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTAQDACSTLLYLLHSPALPENLRQ +QGLDMLADQRE-RGHFAAILPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG +FT--------------------- +>[subseq from] Beta-lactamase, putative n=1 Tax=Synechococcus sp. (strain ATCC 29403 / PCC 7335) TaxID=91464 RepID=B4WI30_SYNS7 +---LKAALQALPDQYTGVPKVFYADVDTGEYV-SVGGEEAIAAASTIKLPILLAFFEDVD +AGRIDLMKTMSMKPEQIASGSGDMQVDPKTQYTALEVASQMIVTSDNTATNMMIDLLGGP +EALNNRFINYGLETTQLNAPLPDLEGT------NLTSARDLAHTMLLISQGESLTVRSRD +HILNILNRTRS-KDLLPATLEKGALTYNKTGDIRS-VLGDIALVDLPNGKRYVVAALVQR +PSND-IRAAELIRQVSDRTY--- +>[subseq from] CubicO group peptidase, beta-lactamase class C family n=2 Tax=bacterium A37T11 TaxID=1855384 RepID=A0A1H8KI18_9BACT +---LRKRILAQTAKFKGHFAVAYKDLQTGETF-FLNEKDSFHAASTMKTPVMAEVFEQAD +KGKFSISDSVTVINKSIVDGSKYSYKLIGKKTTIDDLLQRMITRSSNLATNNLVNLV-GA +KNVMKMMKGIGAKDIKVLRGVEDSK-AYEKGLNNTTTAYDLMLIFEKMAQGTLVNKQSSD +AMIAILKNQYF-KSVIPARLPANVKVAHKTGGLPL-ICHDSGIVYLPDGRKYVLVLLSGD +VPV--EQAKK------------- +>[subseq from] serine hydrolase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013BE45F9 +--GVADRIRAVFADAGCTGWLHARRCGTTAEI-AVDGRDRVVTASVYKLVLFVAFCRRID +DGLIDPGARITVHPADCTPPTGIAALHDPVTMSRRDLATSMMTVSDNAAADILLGEI-GL +GAVEELLAELGLTETRIVGGTADVHRAYDPSYASATTPEDMTRLLQLVWGGGVLSPEQTG +FVRAVMRKQVW-PHRIASAFPRGVFVAGKTGTIGV-IRNEVAVVEFPGEYPIAVAVFTRA +ARADLAVVDAAIAEAARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2W1AUN1_9CHLR +-eQLENTLKDKITIFDGVAGLAVKSLTSEKSI-SINGDEVFPTASTIKVHVLAKLFSLQE +EGKIDLSRRIRFTQDMYGAGSGVIHFLENDPFTFRDVAILMMLASDNTATNICIDIA-GM +EGINDLIRDMGLSKTRLRRKMMDPE-AITRGDENVSTPNDLILMMAQLHNGKP-NPKVSA +QVLQIMSKPKS--DYLNKAVGSEVVVANKPGAMGR-AQGDTGIVFLPNN-PYTVSIMSKF +SMVDSIAQEGFIIDLARTIH--- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. M1575 TaxID=2486009 RepID=UPI000F7986A5 +--------------IGGTTSAYFYDLSSKQSA-TFGADKQQRAASDIKLFIMATVYQSVA +DGKFELNEKYALKDTDKVGGSGALQGMAAGTVSYQDLLKYMMTQSDNTASNILLDKVGGL +SAVNNEIKKLGLTNSVMQRKLMDTKK-LAAGQDNMTTAKDLGRFLTMLYHHQVVSETADS +EMMQLLSQNTN-HSKLPAQVASDVKVYNKTGEFGYGVQNDAAIMEKGGK-AFVVVVLSQN +GTEAT------------------ +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. WAC 01424 TaxID=2203200 RepID=A0A429BPR5_9ACTN +-------FATLFRMAGVTGWLHVRDVDSGREA-GLGADQPVPLASVYKLPLLVEFCRQAD +AGRLDPTTQTTVTPDQRVSGPTGLSAMLDEVMSLRDLAYLMMTVSDNTSADVLLDRV-GM +DDVNTMLDAFGLTGTRVLQSGRAMYEVLDPARTNRSTPREMTRLLAMIWRDEAASPASCA +WMRAVLNMQVW-PHRLASGFPDDVEVGGKTGSLPT-LRNEVGLVEYPDGGRYAVAVFTRS +FGTAQPRADAVIGTAARMAVDH- +>[subseq from] serine hydrolase n=1 Tax=Propionispira raffinosivorans TaxID=86959 RepID=UPI0003A1895D +---LSKQVSTIPIEKNVKYAVYIKNLKVDDKA-VVLNSHKMASASLIKIPIMIEAFNQKN +QGKLNFNEQIVIKHAQAVEGGSVYNLPDGTVLTIGQILDLMIVQSDNTAANILIDKL-KM +ENINAMIQKLGCQDTILQRKMMDFEA-VKQGRQNYTSVTDMANILGKLYTSKCLDPASDK +AMLAIMLRQED-NTVIPAQIPHDLKIAHKTGELD-GMYYDCGIIYGHSSD-YILCIMAEN +VKD-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. PA05 TaxID=2604466 RepID=A0A5D0PPH0_9ACTN +------AFDRLFRAAGVTGWLYAADIDTGHEI-GHGADDPMPTASMYKVPLLVTLARHAD +AGLLALTDRVTVTSHDRVSGPTGLSPMCDDVISLRDLAYLMIAVSDNTAADKLLAQV-GL +DAVNATVRELGLDGTRVVQSAREMNDALDPARANRSTARQMAELFGMIWRDEAATARSCA +WMRGVFNMQVW-PHRLASGFPDDVAVSGKTGTLPT-LRCESGVVEYPDGGRYAVSVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7TB95_9BACT +--ALAQRLAERIARAPARVGLYYRSLAGSDSL-LIGANLRFHAASTMKVPVMIQIFRDAD +AGLLRLDDSLTVHTASLVPAEAFIYESVGRNRSVRDLLELMITRSSNLATNILIERV-GA +VRAQASARALGAWSIQVLRGVEDGQ-AYRAGLNNTTTARDLGVLLIAIVQGRAASRPSCD +SMLAILGRQEF-NEGIPVGVPPGTRVAHKTGWIGEVVYHDAAVVYPARGGPYVLTVLTGG +IKED-SVAHNLVADLSRLVY--- +>[subseq from] Serine hydrolase n=1 Tax=Collinsella sp. WCA1-178-WT-3 (M2) TaxID=2605780 RepID=A0A6A8M423_9ACTN +---LQQDIEALVEPYGGSTSVYAVALDLDGEV-AVAPDARHVAASIIKLPVLACALETVA +AGELSLDEQITVAQQDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANLVIGRL-GM +DTVNETCAALGLTQTVLARLMMDAEAQ-AQGRENYTSARDAAAVLQQLAAGTIATPELCE +RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIIYAE--RPYVLAILTQD +LEREQ------------------ +>[subseq from] Beta-lactamase family protein n=1 Tax=Micromonospora violae TaxID=1278207 RepID=A0A4Q7USB8_9ACTN +-------------------GATVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD +CGQAFLDDGVLVTPQDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF +APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWNAEILTPASRD +LMIQFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG +PM---ATGDETVRRMARTVYD-- +>[subseq from] Imipenem-hydrolyzing beta-lactamase n=1 Tax=Bythopirellula goksoyri TaxID=1400387 RepID=A0A5B9QF79_9BACT +--STEQRLVELAQSVPGTIGYHVALVN-GEVLySHLGDEAFPQASAIKIPLLMEVLAQRE +ERQLDWNALHPILAKHQVGGSGILSEFTDGGLNTADLCTLMIVLSDNTATNMLIDLV-GM +ESVNRRMDSLGLRKTRLNRLMMDTAAS-ARGEENVATPQEACRVMRLLAQGKFIDPEISN +ELLAMLRKPKS--TAIRKAIAAEIPVASKPGAIP-GVATEWAVVELPGQ-PYVMIFMGKE +GS--ENEFNQVFTEMAKCIH--- +>[subseq from] Uncharacterized protein n=1 Tax=Bdellovibrio bacteriovorus TaxID=959 RepID=A0A161PRC4_BDEBC +------------------------------------------------------------ +------------------------------------------------------------ +-RYEAFVKRIQVPTSELKATIEEAFEKYYARGLNSTSLRSFGSLLEKLSQGQILNKKHTE +LVLTYMQKMKTGENRLKAGLPNDILFAQKTGTQV-ARMCNVGIVTSKKNQQKTVIVACAE +KYLDQAGAEKALKKMADALTE-- +>[subseq from] serine hydrolase n=2 Tax=unclassified Pseudoxanthomonas TaxID=2645906 RepID=UPI000F63C438 +--ALEPRLRAIEAALGAGIGVYVLHMERDESY-GYRAGEPWYLASGVKVPVAIAVLREVE +RGTLALDTPVVLRADDFVDGAGATNRHRPGELALSWLLEQMIVHSDNTATDVLIRTV-GL +AAVNRVAAELVDARLRIT------------------------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=2 Tax=unclassified Pseudoxanthomonas TaxID=2645906 RepID=UPI000F63C438 +------------------------------------------------------------ +---------------------------------------------------------AGP +ARVRKLAALLGVPPEQLRQDLAAAFEAYYATGANSATLVDYGRMLATLADGKALGAEATG +WLLERMLRVETGHRRLRAGLPPGIAFAHKTGTQYR-RTCDLGIAMQPDPARVVVAACVRG +TG--TAAGVHALQRIAAAIT--- +>[subseq from] Serine hydrolase n=1 Tax=Microbispora sp. SCL1-1 TaxID=2592812 RepID=A0A544Y958_9ACTN +--------------AGVMGWLHVVDIDDGREV-GLRADEPVVLASVFKVALVLELHRQAE +RGLFDLTERVRVPGADRTGGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLARV-GR +EAVNTLLDGLGLTATRVTQDCREMLTALDPAVANRSTPREMTRLLSMIWRDEAAGAASCA +AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEIGVVEYPDGGRYAVAVFTRS +YGQNQPRADAAIGTAARMAIDQ- +>[subseq from] serine hydrolase n=1 Tax=Nocardia altamirensis TaxID=472158 RepID=UPI0008405C6E +--AAEQRIRAVFADAGCTGWLHARRTDAGAEI-SVDGRDRVVTASVYKLLLFVAFCRHVD +AGRIDATERLTILPSDCTPPTGIAALHDSVTMSLRDLATSMMTVSDNAAADVLLGQV-GL +GPVAALIDELGLAETRVVGGTADQHRAYDPSYTSASTPEEMTRFLRALWSGAVLSPEQTE +FVKSVMRKQVW-AHRIAAAFPSTVRVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLPVVDAAIAEAARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudoxanthomonas sp. SGD-10 TaxID=2493089 RepID=A0A426HB88_9GAMM +--ALEPRLRAIEAALGAGIGVYVLHMERDESY-GYRAGEPWYLASGVKVPVAIAVLREVE +RGTLALDTPVVLRADDFVDGAGATNRHRPGELALSWLLEQMIVHSDNTATDVLIRTV-GL +AAVNRVAAELVDARLRIT------------------------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Pseudoxanthomonas sp. SGD-10 TaxID=2493089 RepID=A0A426HB88_9GAMM +------------------------------------------------------------ +---------------------------------------------------------AGP +ARVRKLAALLGVPPEQLRQDLAAAFEAYYATGANSATLVDYGRMLATLADGKALGAEATG +WLLERMLRVETGHRRLRAGLPPGIAFAHKTGTQYR-RTCDLGIAMQPDPARVVVAACVRG +TG--TAAGVHALQRIAAAIT--- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides eggerthii 1_2_48FAA TaxID=665953 RepID=E5WV58_9BACE +---LTDSISRIVSACPGEIGVAII-INNTDTV-KVNDKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVKIDRNRLDSWSPMMKDYSELVLTVRDLLRYTIAQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHDRAYFNYTSPLGAAMLMNRLFTESIVSGEKQS +FIKNTLKECVTGTDRIVAPLKERVSIAHKTGSGYNGAHNDVAYICLPNNVCYTLAIFVKD +FKGNESQASQYVAHISEVVYS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC30_STAAU +--SHAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTL--------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Azospirillum sp. 47_25 TaxID=1896971 RepID=A0A1Q6UCG3_9PROT +-------------GSGSRVGIAVLS---GDKV-LTVGKGAMPLMSVFKMFVALNVLEHQE +-----KDKVLIVTEEMINRYSPMLKDYPVVPISVAELLKYMVSASDNNATDILLALGGDI +RATQDYVRGLGFPGIVLKVNEQEMHENIRNQYLNRAVPADVVKLLRVVRESERLTNENKR +FFEALMTETATGADKIKKYLPSNVVVGHKTGSSDNGADNDVGFVRLPDGREYYLGVMIAD +SPMSDWDNAELIARISKIVYRHf +>[subseq from] serine hydrolase n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=UPI0010597F42 +----------------HEISVAYLNLGSGSTF-FHNGKTVFHAASTMKTPVMFQLYYMHD +EGELSLEDSLVVRNESIVDGTPFSIENVGNNMTIRDLIEAMITTSSNLATNILIELA-DP +EAVMSTLKEVGAEGVSVIRGVEDLKA-FDQGLSNRTDAYGMMMAMKAVYESELVSDKSRE +EMIGILKRQEF-NEMIPAGLPLGTAVAHKTGWIT-GITHDAAIVMPRNDSPFVLVILTRG +WAVH-DSAVDAGVKISKSVYRY- +>[subseq from] Serine hydrolase n=1 Tax=Fictibacillus sp. S7 TaxID=2212476 RepID=A0A4V1QKL3_9BACI +--ELKNRVNGIIDPLNGEFAYYIET--EEGYI-GKNEEKVFPAASLIKLPILIEAFRQKE +AGLLDLSMPVHINQKDKVGGAGVMNHLSPGALTVLDVLTLMITVSDNTGANVMIEHA-GR +ERINALLTELQCDQTVLERKLMDFK-AIEAGKNNYTSAKDVVLLLKEIHHGKLLQNESRK +MMLDILRNQQF-RHKLPGSMDEAVIIANKTGELQ-GTEHDAAIFEYNGR-IIFAVVLTKN +LTREA-DARHKLAAVGTAIQ--- +>[subseq from] serine hydrolase n=1 Tax=Pricia antarctica TaxID=641691 RepID=UPI000B836E35 +---FEKTVLSQIDSIDGDVAVVFYTLSDPKDSlFINENEKFHAASTMKVPVMIELFKQAE +QGKIDLNDSILLKNESIVDGSSYSYGQIGSKVALRDLMYSMITVSSNLATNVLIELV-GA +KKVTGTMRDLGAENIEVLRGVEDQK-AYNQGLSNSTTAKDLLLIMEGIADGSAGTPEDCE +IMIAILKEQQF-NDIVPFYLPKNVSVAHKTGSIT-GVHHDTAIVFLPDGRSYILVLLSKN +LE-NFDKGTEQLAGISKTVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium GWC2_71_10 TaxID=1798309 RepID=A0A1G0LYZ5_9BACT +--------------------------------aAINADQRFHAASTMKVAVMVQVFRDVD +SGRLTLRQRIPVTNRSLVG--DTLYGHVGGAVEVERLVRLMITVSSNLATNILIEQV-GA +ARVQQTLADLGVDSMQVRRGVEDGP-AFRAGLNNSVTARSLGQLLTAIADGRVASAASCG +RMLRILLDQEF-RDAIPAGLPRRTRVAHKTGWIT-ALHHDAAIVYRDGHPRYVLVVLTRG +LA-EQRASSALIAELARAVH--- +>[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3MIT5_9BURK +--RLQTELTRLDGNGRPTVGVYVRDLDTGEST-SYRAGQRWYIASMVKVPVAIAVLRGIE +RNQFTLDTNVTLRASDYVDGAGPTSRYAGTPLTVRFLLEQMMVLSDNTATDMLIDLV-GL +AEVNAVTQALVPEGFSHITTLGDVRRAYYAEGVNSAQLGAYGELLAKVVDGQALTPRWTA +YLLALMERVQTGTRRVKAGLPAGLRFAHKTGTQRY-RICDAGLVRTAAHQRRVLVVACAR +GDVPFERSEAALMQVGAAL---- +>[subseq from] serine hydrolase n=1 Tax=Microbispora sp. CSR-4 TaxID=2592813 RepID=UPI0011C8DDF5 +--------------AGVMGWLHVVDIDDGREV-GLRADEPVVLASVFKVALVLELHRQAE +RGLFDLTERVRVPGADRTGGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLARV-GR +EAVNTLLDGLGLTATRVTQDCREMLAALDPAVANRSTPREMTRLLSMIWRDEAAGAASCA +AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEIGVVEYPDGGRYAVAVFTRS +YGQNQPRADAAIGTAARMAIDQ- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Staphylococcaceae TaxID=90964 RepID=A0A317ZBE9_STAPS +------------------------------------------------------------ +------------NKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPK------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Aneurinibacillus migulanus TaxID=47500 RepID=A0A0M0H215_ANEMI +-qRLREDVERMVSKVDGKVSVAIE-TDKGHIL--INANDPLPSASLIKVPIMIEAYRQVQ +EGKLNLASKYSLLPEDRVGGMGIVSHLSPELLTLKDLISLMIIISDNTATNAVIRNV-GI +HTVNQLATDLNCGQTVLARMMMDHE-AVKLGKDNITSANDIVRFLKEIVEGSILNEENKK +AAYNTLLNQQF-NTKLPAGFSLNATLAHKTGELP-GTEHDAGVFHINGK-HAYVAVLTTE +LS-DNTSGQRIIAQVGKLVFDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Pricia antarctica TaxID=641691 RepID=A0A1G7ECS8_9FLAO +---FEKTVLSQIDSIDGDVAVVFYTLSDPKDSlFINENEKFHAASTMKVPVMIELFKQAE +QGKIDLNDSILLKNESIVDGSSYSYGQIGSKVALRDLMYSMITVSSNLATNVLIELV-GA +KKVTGTMRDLGAENIEVLRGVEDQK-AYNQGLSNSTTAKDLLLIMEGIADGSAGTPEDCE +IMIAILKEQQF-NDIVPFYLPKNVSVAHKTGSIT-GVHHDTAIVFLPDGRSYILVLLSKN +LE-NFDKGTEQLAGISKTVYDY- +>[subseq from] serine hydrolase n=1 Tax=Sphingobacterium TaxID=28453 RepID=UPI000FBABD5A +-kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFNKIE +KGELQLDQQLLYRASQQYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG +VAINKLMSDLQLAHTRVNSQTEGRKPDWERYGWGQTTPKEMADLVTLIRQGKVVSPKSSD +QMYRFMGNMFY-DERGLSQIPSTVKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN +NTGKTNEAEVLTRKLSKLLWDYy +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q5VUX0_9BURK +--RLVHDLARVSAGHSAGIGVYVRDLETGVAA-RFQSSESWYLASTVKVPVAIAVLRGVE +RGQYKLDTTVTLEASDYVDGAGLTNRNPVGSLTIRYLIDQMIVYSDNTASDMLIGLV-GV +DELNALVRELVPEGFGRITRLAEVRRAYYASGLNSARLDAYGELLARLAQGQALAPASTD +YLLRVMERVATGTHRIKAGLPPAVAFAHKTGTQRR-RFCDAGITY--------------- +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides eggerthii TaxID=28111 RepID=E5X1E3_9BACE +----TDTISKIVAYYPGEIGVAVI-INNTDTI-TVNNKSIYPMMSVFKVHQALAICDDFG +HKGFSLDSLMTIHRDELDPWSPMMKEHLEPVLRVKDLLCYTLILSDNNASNFMFKKLVNI +TQTDSFIATIPRLSFQIAYTEEEMSADHDKAYANYTSPLGAAILMNRLFTDSLIDYDKQQ +FIIKTLEQCSTGKDRIAAPLKDGITIAHKTGSGYTNAHNDVAYIRLPNGICYTLAVFVKD +FKGNETQAAKAIAHISAIVYS-- +>[subseq from] serine hydrolase n=1 Tax=Halomonas sp. TG39a TaxID=1415755 RepID=UPI00068A366F +------------------------------------------------------------ +------------------------------------------------------------ +----ALARALGVSTESFTQDYDHAFDAYEATGENVGTLSAFGDLLASLHHGRALDAEQRQ +TLLALMQRTRSGKQRLKAGLGSGISFAHKTGTQQR-RSCDAGIAESDTEGPWVIVSCTRG +PLA-VSAHERALASVGEA----- +>[subseq from] serine hydrolase n=1 Tax=Halomonas TaxID=2745 RepID=UPI000682A860 +------------------------------------------------------------ +------------------------------------------------------------ +----ALARALGVSTESFTQDYDHAFDAYEATGENVGTLSAFGDLLASLHHGRALDAEQRQ +TLLALMQRTRSGKQRLKAGLGSGISFAHKTGTQQR-RSCDAGIAESDTEGPWVIVSCTRG +PLA-VSAHERALASVGEA----- +>[subseq from] serine hydrolase n=1 Tax=Nocardia shimofusensis TaxID=228596 RepID=UPI000A070EA7 +--AAADRIREVFADAGCTGWLHARRCGGEAEI-SVGGHARVVTASVYKLVLFVAFCRGVD +AGLIDPADRLTIDPADCTPPTGIAALHDPVTMSRRDLATSMMTVSDNAAADVLLGEV-GL +GAVEEVLTDLGLTETRIVGGTADVHRAYDPAYTSATTPEEMTRLLRVLWSGTVLSPGQTA +FVRAVMAKQVW-PHRIAAAFPRGVTVAGKTGTIGV-IRNEVAVVEFPREYPIAVAVFTRA +ARADLPVVDAAIAEAARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A5Q0DQT1_ALCFA +-qRLQERLEPLLSQESARISMAVYATDGTSLF-DWHAQRVMPSASLIKTPMLLCLLEQVA +QGKLSLDTVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM +DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTVQDACSTLLYLLHSPALPENLRQ +QGLDMLADQRE-RGHFAAILPSVARLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG +FT--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536FFR3_9CHLR +--------RERLSSLPGEAAAYVSDASGRELF-SERADEPFPAASVIKLPLVMAIFADAA +RGRVDLDERVAVGE--RVDGSGVLRHMRDVELSLRDLAMLAVIVSDNTATNRLIDRI-GV +ERVNERLREWGCPNTRLARRMYDFAAA-ERGAENLMTARETASLLVRLVRGECEDRATSD +AVVALLAECQD-RTMLRRYLPNAADVANKTGTLDE-SRNDAAIVRGE--PTVVVAAFTRK +LRDTE------------------ +>[subseq from] serine hydrolase n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI000258B24D +--TIQGTIDDAFGDMQGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFISITAYQQVN +EGKLNLNDKYTLKDSDKVNGTGIRNMSSGTEISIQDLLEEMMEDSDNTAANIVIRQLGGM +NKVNTQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN +AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD +GSRDEQ----------------- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus murinus TaxID=1622 RepID=UPI0013A0866E +------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK +IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI +DKVNAQIEKMGAHDTKLQRKMMDTRS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA +EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENENGA-FVVVVLTQN +GDNNEEQ--AA------------ +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus murinus TaxID=1622 RepID=UPI00129839B4 +------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK +IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI +DKVNAQIEKMGAHDTKLQRKMMDTRS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA +EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENENGA-FVVVVLTQN +GDNNEEQ--AA------------ +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2W0AIM8_9BACT +-tALQAKIEALAAQHHGKLTLYASNLKTGATV-AIESDKPVATASVIKLPILVEAMGQVK +AGKRRLSEKITLQKDDIVQGSGILQFFDIPLITLKDALTFMIVESDNTATNLVMDQI-GM +KNVNDRIASMGLKDTYLYKKVPTMPADQKRFGLGKTTAKEMAKVMESIVRCDLKDQELCD +DMLYMLRNQQY-RNLVPHYIETSSLIANKTGSLDE-VRNDVAVVYSKNG-PILISAFTYD +NQNNENAAELLIAHIAKLILETw +>[subseq from] Serine hydrolase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A519FQB1_9BURK +------------------------------------------------------------ +----------------------------------------------------------GA +QRVEALRSALGVPRASLKRTIDEAYARYYEKQLNAATLEGYGAMLEKLVQGKLLKPASME +RLFTDMKIRIFTNYRLQAGLPRSASFIHKTGTQYR-RACHAGVINPQDGAKAIVVATCAA +DIDEQKDAGKVFEQVGRAITR-- +>[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D882CA3 +------------------------------------------------------------ +-----------------------------------------------------------P +ARVTAFARQRADEPVHVDRTKPTLNTAIPGVPHDTTSPRAMAQTLRNLTLGKALGDSQRA +QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ +PQPKAESRRDVLASAAKIVTD-- +>[subseq from] Beta-lactamase BRO-1 n=1 Tax=Halomonas sp. R57-5 TaxID=1610576 RepID=A0A0D6E4R6_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +----ALARALGVSTESFTQDYDHAFDAYEATGENVGTLSAFGDLLASLHHGRALDAEQRQ +TLLALMQRTRSGKQRLKAGLGSGISFAHKTGTQQR-RSCDAGIAESDTEGPWVIVSCTRG +PLA-VSAHERALASVGEA----- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. OV166 TaxID=1882763 RepID=A0A1Y6FU89_9BACI +-dQLKVRIEEELRGLSGRVGLAVEI--EGESL-YVNCEETFQSASLIKVPILIEAFRQSE +AGKLNLNQLVSITN--HVGGSGVLQAFSRDALTLKDLMTLMITVSDNTATNMLIDKL-VM +ADINRSIKKMGLKHTILNRKMMDFA-AIGQGHDNFTIPIDMLTCLKAVNEGSYLKEESRA +AVLKIMSYQQF-QDRLPGLMDERVVVANKTGSLPR-VENDCAVIKYKGKT-AYAAVLIDR +LD-DVYAGKQKISKIGKHIYDY- +>[subseq from] Serine hydrolase n=1 Tax=Lactobacillus murinus TaxID=1622 RepID=A0A4Y9HTK0_9LACO +------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK +IGTIDLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI +DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA +EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENEKGA-FVVVVLTQN +GDNNEEQ--AA------------ +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6K129_9BACT +---LNEELERLSSESKARIAVALHDLESGLRF-SLHGDRWFHAASTIKVVVLLAIFRAAD +EGRLRLDDSLHVRNRFISAGSSFHYQAIGRTTKISALAEGMIASSSNLATNLLLDFL-GV +EYARNVLRDAGVEGVELRRGVEDH-AAHERGINNEATANGLLTLLSA-VRGDFLNSDSKE +QAIRILLQQRF-RSMIPARLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EQDGRRETVAAISEAIYR-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium cellulitidis TaxID=1768011 RepID=A0A235DWA8_9SPHI +-kKLAAKINQAIEGFQGDVGIYVKHLKQNKEV-NINADSIFPTASVVKVPILVGVFQKIK +DGELRLDQKFLYRDSRAYGGSGLMQFFKDSTTDLSTLIGLMLSYSDNVTSIWCQELAGGG +QAINPIMDQLGLTNTKVNSRTVGREDIWKKYGWGQTTPKEMANLYEFIRNGKVVSPAHSD +KMYRFLKNQFY-NERSLSQFPAEISTIDKTGSLDE-SRNEVVLVNAPHGD-FIFSIFTNN +NKTKSNAAENLTKKIANIIWNHy +>[subseq from] serine hydrolase n=1 Tax=Sphingobacterium cellulitidis TaxID=1768011 RepID=UPI000B93DA07 +-kKLAAKINQAIEGFQGDVGIYVKHLKQNKEV-NINADSIFPTASVVKVPILVGVFQKIK +DGELRLDQKFLYRDSRAYGGSGLMQFFKDSTTDLSTLIGLMLSYSDNVTSIWCQELAGGG +QAINPIMDQLGLTNTKVNSRTVGREDIWKKYGWGQTTPKEMANLYEFIRNGKVVSPAHSD +KMYRFLKNQFY-NERSLSQFPAEISTIDKTGSLDE-SRNEVVLVNAPHGD-FIFSIFTNN +NKTKSNAAENLTKKIANIIWNHy +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3C1YUI7_9BACT +--ELKLSIDSIIVTHKGTFAVSFKDISTGVRV-DINAHEYFHAASTMKTPVMIEVFNQAK +QNKFALNDSIPVVNSSIIDGTEYSYNRIGKLETIRNLVVKMITVSSNLSTNILIEKV-GP +ENVMRTLATMGLKDIQVLRGVEDGK-AYDAGKNNTTTSFDLSIIYESIALKKCISKQASE +EMLEILLSQKF-KDMIPAKLPPPVKVAHKTGSITN-VQHDSGIIFLPDGRSYILVVLSKN +LA-SNKEGIEAISSISKRIYD-- +>[subseq from] hypothetical protein n=1 Tax=Collinsella sp. AF31-11 TaxID=2292011 RepID=UPI001314406D +---LQQDVEALVEPYGGSTSVYAVALDLDGEV-AVAPDARRVAASIIKLPILACALETVT +AGELSLDEQITVTQQDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANFVIGRL-GM +DTVNETCAALGLTQTVLARLMMDAEAQ-AQGRENYTSARDAAAVLQRLAAGTIATPELCE +RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD +LEREQ------------------ +>[subseq from] Uncharacterized protein n=2 Tax=Candidatus Gastranaerophilales bacterium TaxID=2137880 RepID=A0A316P627_9BACT +---LENQLENLAALYSIEPAVFVWDYETGNYA-GINSDKLYSAASIIKIPVLIQLFRSIE +AGQLTIYDTMKLTDYYRAEGSGSLQFKAENSWTIDDLARIMITESDNSATNMIMAKLGSM +TDVNSGIRQWGLSKTRVNTWLPDMGGT------NFTTAEDLGRMLYNLDNPNFLSMSSRE +KIFDYMGHVHN-DRLIPAGLGAGAVFLHKTGDIGK-MLGDAGIVYAPNGKKYIVAILANR +PYN-SPLGKDYIVKASEIIYNY- +>[subseq from] serine hydrolase n=2 Tax=Staphylococcus TaxID=1279 RepID=UPI0013F690C7 +------------------------------------------------------------ +------------------------------------LIEASMTYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Serine hydrolase n=2 Tax=Runella sp. SP2 TaxID=2268026 RepID=A0A3G3GRH1_9BACT +-pTLEQNLTDYLAKLSVKVNYRVESLEGKPYA-SLGDDERVPSASIIKIPILVEVMEQVK +AQRFELTDYYTLQNTDKVGGAGIFQEREGKAFTYEQLAHQMMVASDNTATNILIRKV-GR +EAVNERMKTLGFSNLQLNRVMMDTAA-VAKGIENYVNATEINRLLSLIYQRKVATPALCD +LMVAFLLDNQD-TSTLPSLIPRQVGIAHKTGTLTY-IRGDAGIIFTK--KPFVISIFVRG +AD--LSRAETIIAEIGKIGYE-- +>[subseq from] Serine hydrolase n=1 Tax=Collinsella sp. AF31-11 TaxID=2292011 RepID=A0A415UYM1_9ACTN +---LQQDVEALVEPYGGSTSVYAVALDLDGEV-AVAPDARRVAASIIKLPILACALETVT +AGELSLDEQITVTQQDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANFVIGRL-GM +DTVNETCAALGLTQTVLARLMMDAEAQ-AQGRENYTSARDAAAVLQRLAAGTIATPELCE +RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD +LEREQ------------------ +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2D8TCZ0_9SPHN +--------KEIEEETGGRLGVALVDRQGALLL-GFNRDERFAMCSTFKAPLAAAVLTGAD +GGKFGLEGTIPFGKDDVLDYAPVVKKNLKRGMSMEELARAAVEVSDNSAANLLLPMLGGP +EGLTAFMRVHGDDVTRLDRTEPALNENAEGDPRDTTT----------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Porphyromonas sp. COT-239 OH1446 TaxID=1515613 RepID=A0A0A2E0J7_9PORP +---LTDSISRIVSACPGEIGVAII-INNTDTV-KVNDKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVKIDRNRLDSWSPMMKDYSELVLTVRDLLRYTIAQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHDRAYFNYTSPLGAAMLMNRLFTESIVSGEKQS +FIKNTLKECVTGTDRIVAPLKERVSIAHKTGSGYNGAHNDVAYICLPNNVCYTLAIFVKD +FKGNESQASQYVAHISEVVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Trueperaceae bacterium TaxID=2026798 RepID=A0A5Q4G4S4_9DEIN +--TLESRIDHLVAPLPGVTGVVVWRPHDQAPLlTRHADRTFALASVVKLPLLLETLRRAE +RGALDMGERVRLDEADRVAGSGVLHLLDGGLPTLRDLLRLALVVSDNMATDALFARV-PP +SAVETAMHALGYTSLRVPHTIEAMLRA-SPTRGDRATPLDVARMLVDLHAGRVLGGPWRA +LALTILGDCQT-NGRIPARLPEGTRVAHKTGTLRS-RTNDVGIVATPAG-PVVLALFQEG +EP-SERRASAALADVALAVYE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Clostridium sp. KNHs216 TaxID=1550235 RepID=A0A542ANK4_9CLOT +------KILDILNGIPGKTGFYYKNLTTGEKW-EVRSEEPMIAASVIKIPVLAEVFAQLE +AGTADKNELYRIREEDKLPSCGALNMHTGLEVTLEDLYTLMIILSDNTATNLLIKKF-GM +ENINRRMRGLGLNVTTVNRLLFDAGAS-AAGRENRICAKEIGLLLEKMYRGELISPKASQ +EIISILMNQRL-NGKMPFHFKGKVKIAHKTGEDG-GITHDVGIVFAPQ--PFVTCFCSNE +T--DVPLFERAIQDITKLLYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7ZQ35_9BACT +-qRLQASIERTTKSINATWGIYVKSLETSEEI-ALDADRQMETMSTIKIPLMVEAFEQMK +AGKFRLTDKYTFAQADSQPGTGIIQRLDPGALTVKDLITLMVIVSDNTATEVLYRMVGGI +DAVNRRMDAMGLKSTRAMSLPTAWFAREGKHPFGLSTPREMGRLLEMMERGTLVDKASSD +LMLQIMRGQLY-RTRIPRYVT-GYRVPHKTGDFLPFVGDDVGMLEADGR-TIVVSIFTGN +HFGSGEALENAIGLVAKEVADYy +>[subseq from] Beta-lactamase (Fragment) n=4 Tax=Staphylococcus aureus TaxID=1280 RepID=E0XCT9_STAAU +--------------------------------------------STSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNTVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKS------------------------------ +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=Q6UIU7_STAAU +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFG------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A3D2M9J5_PSESP +------------------------------------------------------------ +------------------------------------------------------------ +----AVANALSLSKSELKASMEQAYERYYARNLNSSTLEAYGTLLENLVEGELLSESSRD +LLFKDMKIDRYDGYRLEAGLPSDVPFIQKTGTQLE-RACHVGVIDPEQQATTVIVVACAE +ALDEAKEAGAAFEQVGEAIT--- +>[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus tyrfis TaxID=1501230 RepID=A0A081NXT7_9BACL +-tQLEATIRQAASSVEGKAGIAV-DTAEGQIH--IHADEPFPSASLIKIPILLEAYRQAQ +EGRLDLHQPYAVPSGERVGGTGVIHQLSGALLSLQDLMALMIIVSDNTATNMIIDLI-GM +GTVNKLSDGLGCGATVLGRKMLDFQAK-RNGKDNFTSARDMIIFLKEIVDGSTLKQEAKD +AALQLLRNQQF-NAKLPARMIDKPVLAHKTGELP-GTEHDAGILQVNGK-TAYIAVLTTD +LV-DNLPAQQVISTIGKAVFDY- +>[subseq from] serine hydrolase n=1 Tax=Sediminibacterium roseum TaxID=1978412 RepID=UPI00137B4421 +-kKLESQLNELLKGFNGNMGIYVHDLKKNRIA-AINADTVYPTASMVKVPILAGIMRKIE +DGELQYHQTLTYKDSLLYAGVDILGSFKNGEIELSKVMMLMLTMSDNTASLWLQTLAGTG +TRINQLMDSLGLRETRVNSRTPGREAFRTQNGWGQTTPREMALLMEKIVNKEVVSPSASE +RMLRILGRNYW-DENAISQIPADVFVASKSGAVD-ATRNEVLFVNSKKN-PYIFCICSKN +NKEETNEAWVLTRKVSDLLWKYf +>[subseq from] Serine hydrolase n=1 Tax=Clostridiales bacterium UBA9857 TaxID=2060923 RepID=A0A3B9QDU8_9FIRM +--ECKDQLIEIIKPAGGEWGIVIDALDGEDSI-HLNPEDPFRAASVIKIPIMMAAFHEAR +EGRIRLDDTIILRNQDKVGGCGVLKEHSGLEITLLDAINLMIVVSDNTATNLVIDAV-GK +DLINRYMETKGCTGSWLESQLMR---PKPRGPWNTITAKDIAMLLRGLAERTIENPGDCD +SMVGIMRRQQY-RQKLPRYLPKEAICANKTGEQT-GVTHDAGIITGPKCS-FVIVCLSQN +LD-DTDVGIEVISETAKWAYD-- +>[subseq from] Serine hydrolase n=1 Tax=Lacinutrix sp. CAU 1491 TaxID=2565367 RepID=A0A4U0EQF9_9FLAO +---LKTDITQQINTIEGNVAVAFLDLSNEENSiLINVDEEFHAASTMKVPVMIELYKQQN +QGLINLKDSIVLINKSIVDGSPYKYSKIGTKQTLYDLMVPMITVSSNLATNVLIEIV-DA +KKTTQTMRDLGAEKIDVLRGVEDIK-AYEQGLSNSTTARDLMVIMKAIANGTAGTKADCE +AMLSILKDQQW-NDMIPKYIPDNVEVAHKTGSIT-GVHHDAAIVYPPNGKTYVLVLLSKN +LK-DFDEGTDKLARISERIYNY- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8UI73_9BACT +--PLQDKLRARIAEFPGTVSLYAKNLDTGTAV-GIRESDPVRTASTIKLPIMMAVFDAVD +RRQATWTEPLTVTAAEKVGGTGIIGSEISDGLPLRDVIHLMIVISDNTATNMILERF-PA +DAVNAYLDKIGIRTTRALRRMRDDESQNQEYGLGVSTPRDMVTILEKLQRGEIVNADASR +EMIAILRRCRD-DSGIRRRLR-GISVANKTGSNNS-FRSDVGIAYSNNG-PIAMAISVGG +ISTPDNVGCLLIADLAKMLVD-- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas argentinensis TaxID=289370 RepID=UPI0009F51416 +------------------------------------------------------------ +----------------------------------------------------------GP +KRVEAVANALDMKADQLERDLDEAYRRYYETGVNSATLVAYGQLFGKLAKGELLSDASTE +RLYDIMGLGGYEAYRLEAGLSEQLPFVQKTGTQQH-RACHMGIANPQGDDALVILACAEA +LDED-AEAGKLFEQVGEAI---- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas indica TaxID=137658 RepID=A0A1G9IQ24_9PSED +--RLLEELSRIDTDYPGEIGVFAKDLDSGLSI-SFRGEETWYLASGIKVPVAIAVLRGVE +RGEFTLDDRLRLEAYDYVDGAGETNRHPPGALGVRFLLEQMVIHSDNSASDRLIRLV-GI +EAVNRVVEELAPGGFQPITPLADVRRAYYATQLNSARLSAYGELLEALANGKALGAEGSA +HLMGLMERVATGRKRIKAGLPTVAAFLHKTGTQR-ARFCDLGIVRTADGDKRLIVAACTR +GDSSLARSETALRLVGQAVWQ-- +>[subseq from] serine hydrolase n=1 Tax=Rhodohalobacter halophilus TaxID=1812810 RepID=UPI00083F6A04 +--QLKSDNENHIAEEEGTFGIWFQHLQNPDLHfSINADTLFHAASTMKTPVMIELFRRAE +AGEFDLSDSIEVENKSIVDGSEFQERRVGEMATLYDLNHAMITYSSNLTTNLLIRLV-GA +EETTQTMREMGAENIQVLRGVEDLKA-FEQGLSNRTTPRDLGIIFEHIANGTAVSPTMDS +LMVEVLKDQFY-NDVIPAQLPGDVVTANKTGFIT-GVRHDSAIVYLPDGQSYVLIYLSKN +LP-DGDRGTEIGAEISKMIYE-- +>[subseq from] Uncharacterized protein n=1 Tax=candidate division WOR-1 bacterium RIFOXYC2_FULL_46_14 TaxID=1802587 RepID=A0A1F4U764_9BACT +--ALQGKLLQLTAPHKGKIGIYFLDMNSTFEA-QVYGFNAFPAASTIKLPIMAAAYHLKE +QGKINLGKMVVLRQNDKLGGSGVLQWRKPGLYSLLSLIGYMISFSDNTATKMVEDSV-GL +ASINNYLSSIGMLKTRVTN--PTMLSEPPDPNVNMTTPYEMAYLAAKIAKRSGFNDESAS +DMLYFMHNQRY-KWGIWKGVPPGTYVANKTGNLSR-ILNDVGIVNTKSGA-YVLSIFTWG +FS-SQHNARVLINNVSRVVYEEy +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. PA27(2017) TaxID=1932112 RepID=A0A1Q9Y9K6_9PSED +------------------------------------------------------------ +----------------------------------------------------------GP +QRVEAVANALKMKPDQLERDLDEAYRRYYETGLNGATLVAYGQLFGKLAKGELLSEASTR +LLYDIMGLDSYEAYRLEAGLSEQVPFVQKTGTQQH-RACHMGIANPQGDDALVILACAEA +LDED-AEAGKLFEEVGEAI---- +>[subseq from] Serine hydrolase n=1 Tax=Paenibacillus elgii TaxID=189691 RepID=A0A2T6FS81_9BACL +-nQLEATIRQAASSVEGKAGIAV-DTAEGQIH--IHADEPFPSASLIKIPILLEAYRQAQ +EGRLDLHQPYAVPSGERVGGTGVIHQLSGALLSLQDLMALMIIVSDNTATNMIIDLI-GM +GTVNKLSDGLGCGATVLGRKMLDFQAK-RNGKDNFTSARDMIIFLKEIVDGSTLKQEAKD +AALQLLRNQQF-NAKLPARIIDKPVLAHKTGELP-GTEHDAGILQVNGK-TAYIAVLTTD +LV-DNLPAQQVISTIGKAVFDY- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium BR5-29 TaxID=2607284 RepID=A0A5J5IIN4_9BACT +-kNLQAKIKDLLKGFHGEVGVYVHDLKKNKTV-SINADSIFPTASMIKIPILIGIMDKIE +KGELQYHQPLIYKDSLLYAGEDILGSFKNDEIEMSKVMMLMLTMSDNTASLWLQTLAGTG +TRINELMDSLGMKVTRVNSRTPGRQANQAGYGWGQTTPYEMATLMGKIVKGDIINKEASA +KMLRLLGRNYW-DEEAISQIPTDVFIASKSGAVDE-SRNEVLFVNGKHC-RYIFCICTNH +NQEHNNEAWELTRKLSKMLWSRy +>[subseq from] hypothetical protein n=1 Tax=Geobacillus sp. (strain Y412MC10) TaxID=481743 RepID=UPI0011AB7135 +---------QQAEKNGIRMSVGIRDLSGHETL-LLGSREPYMPASTIKLAVVSALMQQVD +RGELSLADQVTVTPEDVVGGSGSLQTSFPQNLTLERLARLMITQSDNTATNVLIDKV-GM +DNVQQLMDQLDLRTMHLGRKMFAAA--PSPAQDNYIDAADLTELLGQIYQGSFLSVSSRN +QIIAWMARQEV-NTKFGAALP-DAPIAHKTGENTN-VTHDAGYFLVPGHE-LAVSVLLQV +TTEAQRIGNPIVQKAARAIYS-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. CGMCC 1.16541 TaxID=2185143 RepID=UPI000D7376D1 +--SLEERIQTVIDKCRGRVSVAIDMC--PHSI-TIHADTTYSAASLIKVPILLEGYRQVQ +QGVIDLEELVTVPQKDKVGGAGVLTSLSDAALTIKDLLTLMIIVSDNTATNLLIDRL-TQ +QSIHELCRQLDLQHTSLQRKLMDFE-AITKGLDNLTSASDMVKCLKMIDKSQVFEKENRD +RMLHTLQQQQF-YDKLPAKMNRDVSIANKTGELP-GVEHDCAIVHYKDQT-VYVAVLIDE +LD-DNYEGRQIITEIGHLLYTY- +>[subseq from] Beta-lactamase class A n=1 Tax=Rubrobacter radiotolerans TaxID=42256 RepID=A0A023X0W1_9ACTN +------------------------------------------------------------ +-------------------------------GTVRSLSGAMISDSDNVATNLLVDRL-GF +ERINAAAQDLGLKETRLERHMLDFDAQ-AAGRENYTSARDTAALLAEIWHGRTLSPESRE +LALSTLELQTR-RAKIPAALPAGTRVANKTGELP-GVEHDAAIVLVPDRS-FVLVTLTSG +DPDS---GVEAIHA--------- +>[subseq from] Beta-lactamase n=8 Tax=Bacteroidetes TaxID=976 RepID=A0A5M5D4U5_BACOV +---LTDSISRIVSACPGEIGVAII-INNTDTV-KVNDKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVKIDRNRLDSWSPMMKDYSELVLTVRDLLRYTIAQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHDRAYFNYTSPLGAAMLMNRLFTESIVSGEKQS +FIKNTLKECVTGTDRIVAPLKERVSIAHKTGSGYNGAHNDVAYICLPNNVCYTLAIFVKD +FKGNESQASQYVAHISEVVYS-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus murinus TaxID=1622 RepID=UPI000B5C69D8 +------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK +IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYHELLAYMIDESDNTAANIMIDALGGI +DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA +EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENENGA-FVVVVLTQN +GDNNEEQ--AA------------ +>[subseq from] Uncharacterized protein n=1 Tax=Fictibacillus enclensis TaxID=1017270 RepID=A0A0V8J1G5_9BACI +--ELKNRVNGIIDPLNGEFAYYIET--EEGYI-GKNEEKVFPAASLIKLPILIEAFRQKE +AGLLDLSVPVHINQKDKVGGAGVMNHLSPGALTVLDVLTLMITVSDNTGANVMIEHA-GR +ERINALLTELQCDQTVLERKLMDFK-AIEAGKNNYTSAKDVVLLLKEIHHGKLLQNESRK +MMLDILRNQQF-RHKLPGSMDEAVIIANKTGELQ-GTEHDAAIFEYNGR-IIFAVVLTKN +LTREA-DARHKLAAVGTAIQ--- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=C2Q4I5_BACMY +------------------------------------------------------------ +----KLDKVNTYIKDDLVEYSPITEKHVDTGMTLGEIAEAAIRYSDNTAGNILFKKLDGP +KGFEKELGQNGNKVTLADCFELDMKEAIQGDICDTSTAKTLAFNLKALTVRNALQTDKRK +IPTDWMRGNATGDELIHAGVPKDWEVDDKSGAGSYGTPNDIAIV---------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Lentibacillus halodurans TaxID=237679 RepID=A0A1I0W4M4_9BACI +-nQLETEVHSIISGIDAPIGLVIKE--RNHSI-NVNENMPMPAASVIKIPIIMEAFRQAE +IGDLILSETLNIPAEAKVGGSGVLQTMSKDVITLLDVLTLMITVSDNTASNLALERV-GI +SNVNRLCRELEHHNTEIQRYFMDTKAA-EKGLENMTTAIDMVNFLEEIASPQLLNQDSAN +RILQIMSQQQLTSKLPAYHIIDDVMIANKTGELVN-AEHDVAIFQYKGR-TLFAAVMVNE +VS-DQVEAQQTIANIGKEVMAY- +>[subseq from] hypothetical protein n=1 Tax=Geobacillus sp. (strain Y412MC10) TaxID=481743 RepID=UPI0011A51C22 +-----------AEKDGIRMSVGIRDLSGHETL-LLGSQEPYMPASTIKLAVVSALMQQVD +RGELSLADQVTVTPEDVVGGSGSLQTSFPQNLTLERLARLMITQSDNTATNVLIDKV-GM +DNVQQLMDQLDLRTMHLGRKMFAAA--PSPAQDNYIDAADLTELLGQIYQGSFLSVSSRN +QIIAWMARQEV-NTKFGAALP-DAPIAHKTGENTN-VTHDAGYFLVPGHE-LAVSVLLQV +TTEAQRIGNPIVQKAARAIYS-- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas sp. PA27(2017) TaxID=1932112 RepID=UPI0009F83DB8 +------------------------------------------------------------ +----------------------------------------------------------GP +QRVEAVANALKMKPDQLERDLDEAYRRYYETGLNGATLVAYGQLFGKLAKGELLSEASTR +LLYDIMGLDSYEAYRLEAGLSEQVPFVQKTGTQQH-RACHMGIANPQGDDALVILACAEA +LDED-AEAGKLFEEVGEAI---- +>[subseq from] Serine hydrolase n=2 Tax=Lactobacillus TaxID=1578 RepID=A0A358LUP3_9LACO +------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK +IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI +DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA +EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENEKGA-FVVVVLTQN +GDNNEEQ--AA------------ +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Aminicenantes bacterium TaxID=2052149 RepID=A0A3N5SPW1_9BACT +--ELEQAVAAQAGKIKGRTGVFIKHVESGETV-GLRDGERFQLASVFKIPVLMTLHKEIR +LGRISLDDRIMFEERMKTYGSGLMTSMKPGLISVQDLQLLMMAKSDNTATDILFDLV-TP +EAVGATIAGLGLKDTTVDYNTRQLILTFDASTHDTSTPRDIATLLEKCVKGEFVDRETGD +RVLETMKHH-TGAELILRYLPESTDVARKGGSLGRGVLNDCAVVWLPEKGTLIICFFGND +LREIHYEIKHKVGLMARAAYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Pseudohongiella spirulinae TaxID=1249552 RepID=A0A0S2KGK2_9GAMM +---LRETLQQAGDGIRVSVGVSALEGGSGATL-LMGDALSYAPASTIKMLLVASLMQQVD +AGLLTLQQTTTVSPADVVGGYGVLQEEAQPQVTLGRLAELTVTISDNTATNVLVDVV-GY +PAMAGLAAQLGLELMHFGRKMFEAPE--PPAKDNYINAPDALALLTAIYSGTLLSDDSRD +QIMRWLSAQTV-RTKIAAGVPDGVKVAHKTGENGP-VSHDIGFIMLPDST-LAVAIFTEN +LKASQALLNPLVAEITSTIYRH- +>[subseq from] Serine hydrolase n=1 Tax=Lactobacillus animalis TaxID=1605 RepID=A0A4P8K6F6_9LACO +-------------------TVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK +IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI +DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA +EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENEKGA-FVVVVLTQN +GDNNEEQ---------------- +>[subseq from] Uncharacterized protein n=1 Tax=Globicatella sp. HMSC072A10 TaxID=1739315 RepID=A0A1E8YZ06_9LACT +----------------GEYSLYYQALDTSSQP-LILNNQPMRSASIIKLFVLAALFEQVE +KGELDLTEQYSLKAEDKVSGTGDIQNMEDGSLTLLTLAEKMMTISDNSATNILINLMGGI +EKVQKIIIELGYSDVQLKRLMVDLE-ALNAGNDNYVTAEDVGRILADIYQGKLVSKSASQ +EMLAILKQQTD-RRMLAQNLPSDVAYYGKTGNFDYGVQNDAAIIETPKGA-FILVFLSQE +GQ--KEQQLKAMNQLGKIVSEQf +>[subseq from] Serine hydrolase n=1 Tax=Rhodohalobacter sp. SW132 TaxID=2293433 RepID=A0A371QT08_9BACT +--ELRDSIESILDNEEGTYAVYFSDLDDSQIElTINPDTLFHAASTMKTPVMIEVFRRAD +AGEFSVYDSIRIDNRSIVDGSEFSERMEGEMATIYDLTNAMITYSSNITTNLMIDLV-GA +EETTRTMRELGAENIEVLRGVYDMKA-FEQNLSNRTTARDLAIIFRSIADGTAADRESGQ +LMIDILSDQFY-RDIIPKYLPEELIIANKTGSIS-GVEHDSGIVYLPDGRSYLLIYL-SK +NVPDDEHSRDVGARISELIYDFy +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas fulva TaxID=47880 RepID=UPI0005ACC3DE +------------------------------------------------------------ +----------------------------------------------------------GP +QRVEAVANVLDLQTDQLESDLDEAYSRYYDSGLNSATLVAYGQLLGKLATGDLLNGDSSA +LLYDIMGLGGYDAYRLEAGLNEDLPFIQKTGTQQH-RACHMGIANPQDERALVIVACAED +LDE-NDEAGTLFEQVGEAI---- +>[subseq from] Beta-lactamase n=1 Tax=Collinsella aerofaciens TaxID=74426 RepID=A0A381K4Z3_9ACTN +---LQQDIEALVEPYDGSTSVYAVALDLDGEV-AVAPDARRVAASIIKLPILACALETVT +AGELSLDEQITVTQQDIVGGSGNIQSRGAGVYGIDELLHAMIAQSDNVAANLVIGRL-GM +DTVNETCAALGLTQTVLARLMMDTEAQ-AQGRENYTSARDAAAVLQRLAAGTIATPELCE +RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD +LEREQ------------------ +>[subseq from] serine hydrolase n=1 Tax=Streptosporangium roseum TaxID=2001 RepID=UPI0004CDAB9E +-----------FRAAGVTGFLHAVDLDTGAEV-AHGADEPVVMASVFKLALLVEFFRQTD +AGRLDVTERVTVMADRHTPPTGVSAMADDVTMSLRDLAYLMIAVSDNTAADTLVGRV-GL +SAVNTMLAAEGLDGTWVEHDCRSLFAALDPARTNRSTPRDMTRLLGMVWRDEAASAASCA +SMRRLLGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-IRNEVGVVEYPDGGRYAVAVFTRS +TAQNQPRADAVIGTAARAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Nonomuraea sp. SBT364 TaxID=1580530 RepID=UPI00066CD5EA +------DLEALFRAAGVRGWLLAADIDTGREI-GHGADEPVPTASMFKVPLMVEFCRQAD +AGLLDPASRVTVTGADRVGGPTGLSAMLDDVISLRDLAYLMIAVSDNTAADVLLARV-GM +EAVNAMLDGFGLTGTRVLQSAGETNSVLDPPRTNHSTARELARLFGLIWRDEAASPSSCA +WMRGVLNLQVW-PHRLASGFPDDVAVSGKTGTLPT-LRGEAGVVEYPDGGRYAVAVCTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] serine hydrolase n=1 Tax=Rubrobacter radiotolerans TaxID=42256 RepID=UPI00068A3012 +------------------------------------------------------------ +-------------------------------GTVRSLSGAMISDSDNVATNLLVDRL-GF +ERINAAAQDLGLKETRLERHMLDFDAQ-AAGRENYTSARDTAALLAEIWHGRTLSPESRE +LALSTLELQTR-RAKIPAALPAGTRVANKTGELP-GVEHDAAIVLVPDRS-FVLVTLTSG +DPDS---GVEAIHA--------- +>[subseq from] Beta-lactamase n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=A0A1Y0VX55_PEDPE +--TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN +EGKLNLNGKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM +DKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN +AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD +GSRDEQ----------------- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5YW28_9BACT +--TLTEEVERLAAESKARTAVSVHDLESGLRF-SLRGDRWFHAASTIKVGVLLALFRAVD +EGRVRLDDSLHVRNHFFSAGSAFQYQAIGRTAKIAALAAGMITASSNLATNLLLDFL-GV +AYARNVLRDAQVQGVELRRGVED-HAAHEKSINNEATADGLVALLSAL-RGDFLRSESKE +QAIRILLEQRF-NSMIPAGLPPHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EREGRRETVAAISEAIYH-- +>[subseq from] Putative beta-lactamase n=2 Tax=Collinsella aerofaciens TaxID=74426 RepID=A4EC45_COLAA +---LQQDIEALVEPYDGSTSVYAVALDLDGEV-AVAPDARRVAASIIKLPILACALETVT +AGELSLDEQITVTQQDIVGGSGNIQSRGAGVYGIDELLHAMIAQSDNVAANLVIGRL-GM +DTVNETCAALGLTQTVLARLMMDTEAQ-AQGRENYTSARDAAAVLQRLAAGTIATPELCE +RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD +LEREQ------------------ +>[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD048 TaxID=1053226 RepID=J8HHN6_BACCE +------------------------------------------------------------ +----KLDKVNTYIKDDLVEYSPITEKHVDTGMTLGEIAEAAIRYSDNTAGNILFKKLDGP +KGFEKELGQNGNKVTLADCFELDMKEAIQGDICDTSTAKTLAFNLKAFTVRDALQTDKRK +IPTDWMRGNATGDELIHAGVPKDWEVDDKSGAGSYGTPNDIAIV---------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea polychroma TaxID=46176 RepID=A0A438MNR8_9ACTN +-------FETLFRMAGVTGWLYAADIDSGREV-GHGADEQLPTASMFKVPLLVEFCRQAD +AGLLDPTSRVTVTAGDRVPPTGISAMLDDVTISLRDLAYLMIAVSDNSSADVLLGRV-GI +DAINAMLARHGLMSTRVSQSAKEINEALDPARANRSTPREMARLFGLIWRDEAASVASCA +WMRAVLNMQVW-PHRLASGFPDDVAVSGKTGTLPT-LRTESGVVEYPDGRRYAVAVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea pusilla TaxID=46177 RepID=A0A1H8B8I9_9ACTN +------DFAALFHAAGVTGWIHARDLDTGREV-GLGPDEPLPTASMFKVPLLVEFCRQAD +AGLLDPASRVTVTAADRVSPTGVSGMLDDVTISLRDLAYLMITVSDNTAADVLLARV-GM +DAVNRMLDGFGLHVTRVVMSGRVMLGVLDPARTNRSTPREMATLLGLVWHDRAAGAASCA +WMRGVLGMQVW-PHRLASGFPDDVAVSGKTGTLPT-LRGEAGVVEYPDGGRYAVAVFTRS +YSLNQPRADAVIGTAARMAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A3G6HHI5_ALCFA +-eRLQERLEPLLTQESARISMAVYATDGTSLF-EWHAQRVMPSASLIKTPMLLCLLEQVA +QGKLSLDTVYPLPEGDRTPGTGILSQLPGVLLSLRELALLMIILSDNVATNALIDLL-GM +DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTAQDACSTLLYLLHSPALPENLRQ +QGLDMLADQRE-RGHFAAILPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG +FT--------------------- +>[subseq from] serine hydrolase n=1 Tax=Xanthomonas citri TaxID=346 RepID=UPI00124526F3 +------------------------------------------------------------ +---------------------------------------------DNMAIVRLRNAEAGE +PRLMALARELGVPRSALKASLDDVFDAYYAGDRNHATLPAFATLLERLAAGELLSPESTQ +RMLDHMRAISTGDRRLSAGLPPGTDFAQKTGTQLR-RACNVGVIDAAAGAGATVVLACAE +DFDELAQAEQAFQAFGRAL---- +>[subseq from] Serine hydrolase n=1 Tax=Streptosporangium sp. 'caverna' TaxID=2202249 RepID=A0A2Z3ULG8_9ACTN +------AIEGLFRTAGVTGSLHVVDIDTGAEV-AHDADESVVVASVFKVALLVELFRQAD +RGVLDPAERVTVMADRHTAPTGVSVMADDVTMSLRDLAYLMIAVSDNTAADAVIDRV-GL +PAVNTMLAAFGLDRTWIEHDCRELFSALDPARTNRSTPRDMTRLLGMIWRDEAASPGSCA +SMRRLLGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-IRNEIGVVEYPDGGRYAVAVFTRS +TAQNQPRADAVIGTAARAAVE-- +>[subseq from] Beta-lactamase class A n=2 Tax=Salegentibacter TaxID=143222 RepID=A0A1I2NEB2_9FLAO +-eELQHTIDSIFKITQGDFAIAFKDLSEEKNSiFINHHEDFHAASTMKTPVMIEVFKQAS +AGKFALQDSLIVKNQSILDGSSYSYEQIDQKRSIEDLVTDMIIYSSNLATNIIIELV-DA +KNVNKTMRNLDAKNINVLRGVEDMK-AYEAGLSNSTTAYDLMLIFEDLATGNAVNPEADE +KMLNILRQQKH-TDLIPHLLPENLKIANKTGWIT-GVHHDSALIELPDGRKYVLVLLSKN +ME-DMDTGTKMLNQVSKMIYEH- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI00132FDC18 +--TIQGTIDDAFGDMQGETSVYVSPTDSTGEV--VSNSKAQRAASNIKLFILITAYQQVN +EGKLNLNDKYTLKDSDKVNGTGIRNMSSGTEISIQDLLEDMMEDSDNTAANIVIRQLGGM +DKVNTQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN +AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD +GSRDEQ----------------- +>[subseq from] Uncharacterized protein n=2 Tax=Sphingobacteriia TaxID=117747 RepID=A0A258WSR7_9SPHI +-qKTEKDLQTIMATSPSLSGLMAVDLSSGESI-SINENVVFTQASAIKIPILMEVYKQAH +EKKFALTDIKPLLPSNTVAGSGILNVMVDPVLSIRNLCVLMIGLSDNSATNTLIELV-GM +KNVTNTMQSLGFSNTRLQRKMIDQPAS-LRNEENISTPAEAVRIMKLLYEGKFIDKSTSD +EILSILMNNPVANSKIADGISANVKIAFKPGGMG-GVSTEWAIVYLSNR-PYAITIMENY +KT--SATPSNIISALSKRVFDYf +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Bacteroides pyogenes TaxID=310300 RepID=UPI0011E40F8B +---LTDSISRIVSACPGEIGVAII-INNTDTV-KVNDKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVKIDRNRLDSWSPMMKDYSELVLTVRDLLRYTLAQSDNNASNLMFKDMVNV +AQTDSLIATIPRSSFQIAYTEEEMSADHNRAYSNYTSPLGVAMLMNRLFTESIVSGEKQS +FIKNTLKECVTGTDRIVAPLKERVSIAHKTGSGYNGAHNDVAYICLPNNVCYTLAIFVKD +FKGDESQASQYVAHISEVVYS-- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus murinus DSM 20452 = NBRC 14221 TaxID=1423772 RepID=A0A0R2BR46_9LACO +------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK +IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI +DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA +EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENEKGA-FVVVVLTQN +GDNNEEQ---------------- +>[subseq from] Serine hydrolase n=1 Tax=Ornithinibacillus sp. TaxID=1898027 RepID=A0A3C1I1S4_9BACI +-kSLTETIQKVVDDAGGLWGISLLDLDTNDSW-ELNEHELFYAASVIKVPIMIAAFAASH +NGEMELSKKVVLKREDIVGGSGVLQYMTPGTVAIYDLITLMIIQSDNTATNLLVDLI-GT +EKIQQEMENIGLEKSCYYHKMMIGS--VDRKEFNQITAAEMTMMLKKLVTGKIVSIHACE +QMIDIMKKQQI-RHTLPSKIEKEFEIAHKTGNVL-GIRHDIGIFYVGQRK-MIASILSKG +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Nocardia amamiensis TaxID=404578 RepID=UPI00082DE872 +-----ERIRAVFADAGCTGWLHARRCDSAAEI-SIGGRERVVVASVYKLPLFVAFCRSVD +AGRIDPTARLTVTPSDCTPPTGIAVMRDPVTMSLRDLATSMMTVSDNAAADVLLGAT-GL +GAVEELLDQLGLTQTRIVGGTADLHRAYDPSYTSATTPEEMTRFLRALWSGTVLSAEQTE +FVRSVMRYQVW-PHRIAAAFPRSVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLPVVDAAIAETARIAVT-- +>[subseq from] hypothetical protein n=1 Tax=Lactobacillus TaxID=1578 RepID=UPI000826B1BC +------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK +IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI +DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA +EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENEKGA-FVVVVLTQN +GDNNEEQ---------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC62_STAAU +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKT---------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium sp. Ag1 TaxID=1643451 RepID=A0A0M2XYJ7_9SPHI +-kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE +KGELQLDQQLLYRSSQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG +IAINQLMSSLQLPHTRVNSQTEGRKPDWEKYGWGQTTPKEMADLVTLIRQGKVVSSKSSD +QMYRFMGNMFY-DERGLSQIPSTIKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN +NTGKTNEAEILTRKLSKLLWDYy +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI001378CFF1 +------------------------------------------------------------ +-------------------------------LTAPELARATQLTSDNAAANLLIRKLGGP +EAVTALWRASGDEVSRLDRLEPDMNLLPPGDLRDSTSPRAMAQHVARLFTSEMLVPEDRE +RLREWMVETGTGLARLRAATPPHWQAGDKTGSAIPNKTHDVAVFWPPGRAPVIVAAYYES +DAHHRAQDEAVLAQVGRIAV--- +>[subseq from] Uncharacterized protein n=2 Tax=Sutterella sp. AM11-39 TaxID=2292075 RepID=A0A415CH74_9BURK +--ASQAAIVALEKKYDAAIGVSLRDAKGKVLL-EWRSRERFPLTSTVKALECARVYELGL +-----ENHYAPIKTTPIVPHSPVYGKDPDTQVTLKEACRAALSQSDNRAANFIFVHTGGP +KALTEWLRQKGDNTTRSDRLEPDLNLSGKNEYRDTTTPSNASLNWQRF--DSTLPQAARE +QWLSDLASNQMAGNLFRSRLPENWTLYDRSGAGSDETRANHAILVTDKGVRYYAAVHLKA +PATPMEKRDAILQQAIEVVYAH- +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5MKI1_9BACT +---LHEELEALALKNKARIGVALHDLQTGFRF-SFRGDRWFHAASTIKVAVLLAVFRAAD +EGQFRLDDSLHVRNRFFSAADGSLYAAIGRTAKISSLAHAMICGSSNLATNLLLEFV-GV +EYARTVLRDAQVDGVELRRGVEDH-GAHEQGINNEATADGLLRLLS-VIRGDFLTPESKR +EVIRILLEQRF-NSMIPAGLPPHATVAHKTGETST-ACHDIGIIYLPEREPYIAAILTEF +DP-EREGRRETVAAISQAIYR-- +>[subseq from] Serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A3D0L3K0_ALCFA +-eRLQERLEPLLNQESARISMAVYATDGTSLF-DWHAQRVMPSASLIKTPMLLCLLEQVA +QGKLSLDTVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM +DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTAQDACSTLLYLLHSPALPENLRQ +QGLDMLADQRE-RGHFAAILPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLTVMADG +FT--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Lawsonibacter asaccharolyticus TaxID=2108523 RepID=A0A2P2F742_9FIRM +----QNEIYRILSGLAGTVGLYVEDCQSGEIF-TINPEHVFPSASVIKVPMLALLMRDAQ +QGLVDLDAPRTIDPRNRVGGTGILCELGTDYPSLRDLAKLMIVLSDNIATNEIMDVI-GM +ERFNSFCREMGYQNITLMRKMMDFE-AIQQGKNNYMCAGETGRLLSAISRGEFVNPEISQ +TIFDIMASQQC-RNKLPALLPAVVLVANKTGDLV-GIQHDVGIFELPDGRRYLIAMFTGD +LEND-SAGIAAISQVSLAVYQ-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4Y5QAR4_ECOLX +--DVQQNLAELERQSGGRLGVALINTADNSQI-LYRADERLAMCSTSKVMAVAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP +ASVTAFARQLGDETFRLDR----------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Cyanobacteria bacterium UBA11440 TaxID=2055784 RepID=A0A359BLT6_9CYAN +--ELENSLKALNNKYNIKPAVFVWSMDNSNYV-DIGGDVVYPSASIIKLPVLIQMYKSIE +AEQFGLKDNMTLTEYYRSEGSGNMQYSQAGRYSITDLATTMIQDSDNTATNMLISKVGSM +NDVNAAIKSWGIEHTHLQTWLPDITGN------NYTTAKDIAQMLYNIGKNKFLNINSQS +DIINIMSKVKN-TMLIKAGLPENVSFIHKTGDIGT-MLGDAGIVYLPSGQRYIVVILALR +PHNN-INGRLYIQEASKIIYNY- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6GN37_9BACT +--TLREALEKLARESKARVAVALLDLESGFRF-SLAGDRWFHAASTIKLAVLLAIFRAAD +ERRLRLDDSLHVRNHFVSAGSPFRYQAIGRTAKISALTEGMIVASSNLATNLLLDCL-GV +EYARNVLRDAQVSGVELRRGVEDQ-AAHEKGIDNEATADGLLTLLSAL-RGDFLKKESKE +QAIHVLLAQRF-NSMIPAGLPAHATVAHKTGEIST-ACHDVGIVYLPEREPYIAVILTEF +DA-EQNGRRETVAAISEVIYR-- +>[subseq from] Serine hydrolase n=2 Tax=Lactobacillus sp. CBA3606 TaxID=2099789 RepID=A0A2R3JV09_9LACO +--TIRQAINTSLSGLKGTTSVAVAATASSAKV--VQNDQSQRAASLIKLFILITAYEQAD +SDQLNLDETYTLTANDKVGGTGTLQGLPTGSLSYREILKRMMDESDNTAANIMIDKVGGI +STVNAEIERLDLSKTQLERKMMDTD-ALADGKDNYTSVTDVATVLTKMYAGKLISPTADQ +AMLTIMRQNAN-HAKLPHDLPSAAIIYNKTGEYDYGVQNDAAIIKNKHGA-FVVVVLSQG +GDEAA--QV-------------- +>[subseq from] Uncharacterized protein n=2 Tax=Rubricoccus marinus TaxID=716817 RepID=A0A259U2R5_9BACT +-dALRQRIEAIAARYEATVAVAVRD--GETRL-DIAADRPFHAASTMKVPVMIEAFRQVE +AGRLAWDDSIDVVNRSIVDGSPFSYERLGTRMPLADLTRRAITTSSNLATNLMMEVL-TA +DSVQATTRALGGEGVLVLRGVEDLKA-FDAGLSNLATARGLAALMLAIQDGRAVSPEASG +DMVEILLAQEF-GEMIPAGLPAGVRAAHKTGWITH-VHHDAAIVYPPEAAPYVLVILTEG +ID-DHGRAAALGAEIAAAVH--- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8V8B3_9BACT +---VEDALRARIGDFQGTVSLYAKNLDTGSTT-GIRESDAVRTASTIKLPIMLAVFDAVA +RGQAKWTEPLTVTADEKVSGSGVIGSEISDYLPLRDVLHLMIVLSDNTATNMILERF-TA +DAVNAYLDKIGIKTTRSLRKVRDGNQENQKYGLGVTTPRDMVTILEKLERGEIVSPDASR +EMIAVLKRCQD-NSGIRRPMG-DVPVANKTGALD-ALRSDVGIVYSKGG-RIAMAITVDG +MPTPDNTGTILIADLARILVD-- +>[subseq from] CfxA family class A beta-lactamase n=1 Tax=Bacteroidales bacterium 52_46 TaxID=1897040 RepID=A0A1Q6EF40_9BACT +--QLRDSLSHIAGEYPGEIGIALL-TSAGDTV-VVADEDKYPLMSVFKLHQAISLCRLFD +EQGASLDTVLEIPRRKLNPWSPMLKDYTADPISVRDMLRYTLTQSDNNASNYLFETVEPV +AAADSFISTIPRAGFRIVATEAEMFDNHALCYENHSSPLGAALLIDRLFTDSIIDTASRD +FICTTLGQCTTGTDRIVAPLADGVTVAHKTGSGFRNAHNDVAFVTLPDGTSYSLAVFVKD +FNGSEQEAARAIARISSTIYT-- +>[subseq from] serine hydrolase n=1 Tax=Atopobium sp. Marseille-P4126 TaxID=2094145 RepID=UPI000D558AD7 +--ALKSELEQVVAPYGNAVSISVADIRTGATC-DINANKQVISASMIKLAVMAAYLQAVD +AGTINPQQALPLARMKIVGGTGKIQSERARTYTYDALCRYMIMYSDNTATNALIDAL-GV +NTVNTRARELGCTQTTLNRKLMQLNTG----VENYTSAADVSRLLCAFYTQTAASAGQCT +KAMDFLLQQTD-GDGIPQGLS-GVQFAHKTGTLG-GIRHDGGIVMA--RSPYTIVVMCEL +PEG---KANALMTQVARKTQQYf +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gastranaerophilales bacterium HUM_9 TaxID=1916320 RepID=A0A292RGZ2_9BACT +--ELENSLKALNNKYNIKPAVFVWSMDNSNYV-DIGGDVVYPSASIIKLPVLIQMYKSIE +AEQFGLKDNMTLTEYYRSEGSGNMQYSQAGRYSITDLATTMIQDSDNTATNMLISKVGSM +NDVNAAIKSWGIEHTHLQTWLPDITGN------NYTTAKDIAQMLYNIGKNKFLNINSQS +DIINIMSKVKN-TMLIKAGLPENVSFIHKTGDIGT-MLGDAGIVYLPSGQRYIVVILALR +PHNN-INGRLYIQEASKIIYNY- +>[subseq from] serine hydrolase n=1 Tax=Algoriphagus antarcticus TaxID=238540 RepID=UPI000A370282 +-kQLESSIRELAMSFQGDIGIYIKNLKTGASV-EINSDSIFPTASIVKIPILLAVFDKIE +KGELHYREPLIYRDSIKYGGSGIMQFFKDSTTDLSTLIALMLSYSDNTTSLWNQALAGGG +AQINEVMEQLGYNNTRVNSRTPGRESIWEKYGWGQTTPKEMADILERLNNKELISPAASE +QMYRLLSNTFY-TDYALAGIPAGINVASKQGMVD-ASRSEVFLVNSPQGD-YVCAIFTKN +NKDHDNEVWVLTRKISNLIWNHf +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6HJM8_9BACT +---LHEELEALALKNKARIGVALHDLETGFRF-SFRGDRWFHAASTIKVAVLLALFRAAD +EGRFRLDDSLHVRNRFFSAADGSLYAAIGRTAKISSLAHAMICGSSNLATNLLLEFV-GV +EYARTVLRDAQVDGVELRRGVEDH-GAHEQGINNEATADGLLRLLSAI-RGDFLTPESKR +EVIRILLEQRF-NSMIPAGLPPHATVAHKTGEIST-ACHDIGIIYLPEREPYIAAILTEF +DP-EREGRRETVAAISEAIYR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus antarcticus TaxID=238540 RepID=A0A3E0DZB6_9BACT +-kQLESSIRELAMSFQGDIGIYIKNLKTGASV-EINSDSIFPTASIVKIPILLAVFDKIE +KGELHYREPLIYRDSIKYGGSGIMQFFKDSTTDLSTLIALMLSYSDNTTSLWNQALAGGG +AQINEVMEQLGYNNTRVNSRTPGRESIWEKYGWGQTTPKEMADILERLNNKELISPAASE +QMYRLLSNTFY-TDYALAGIPAGINVASKQGMVD-ASRSEVFLVNSPQGD-YVCAIFTKN +NKDHDNEVWVLTRKISNLIWNHf +>[subseq from] Beta-lactamase n=1 Tax=Pseudomonas fulva TaxID=47880 RepID=A0A0D0KS46_9PSED +------------------------------------------------------------ +----------------------------------------------------------GP +QRVEAVANVLDLQTDQLESDLDEAYSRYYDSGLNSATLVAYGQLLGKLATGDLLNGDSSA +LLYDIMGLGGYDAYRLEAGLNEDLPFIQKTGTQQH-RACHMGIANPQDERALVIVACAED +LDE-NDEAGTLFEQVGEAI---- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacterium sp. TaxID=1872119 RepID=A0A2G4JHV2_9BACT +--TLSDRIAALTRGFNGTVAIYARNLDTGQDF-AVGADTRVRTASTIKLPILCALEDLVA +KGRIAWTLPVPVRAEDRVSGSGVLAESPGATLPLRDVATLMIIVSDNTATNLVIDRI-TA +DAVNDYLDTLGLTATRSMRKVRGDGTQQPENQRGSSTPREMVRLLELLEQGQVVSPTASK +NVLDLLKRQQF-KTGIGRRVGGDVQVASKSGALD-ALRSDVGIAHTKGG-RIAMAITVDD +MPSPDNAGEELIWEISKVLM--- +>[subseq from] serine hydrolase n=1 Tax=Nocardia carnea TaxID=37328 RepID=UPI0002D36700 +---VAERIHAVFADAGCTGRLHARRCDGGTEV-SIGGTERVVTASVYKLPLLLAYCRAVD +AGRIDPLQRLTLTPAECTPPTGISALHDPVTMSRRDLATSMMTVSDNAAADLLLGEI-GL +ADVHDLLTSLGLTRTRLVGGTADIQRAYDPAYTSATTPEEMTRLLSALWRGEVVSAQQTD +FARAVMRRQVW-PHRIAAGFPRAVSVAGKTGTIGI-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLPAVDAAIAEAARIAVT-- +>[subseq from] Uncharacterized protein n=1 Tax=Microbispora catharanthi TaxID=1712871 RepID=A0A5N6C231_9ACTN +--------ERVFRNAGVTGWLHAVDIDDGREV-GLRADEPVVLASVFKVPLLLELHRQAE +RGLLDLTERVGVPAADRTSGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLARV-GR +EAVNTLLDGLGLTATRVVQDCRDMLTALDPAVGNRSTPREMTGLLAMIWRDEAAGAASCA +AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +LSQNQPRADAAIGAAARMAIDQ- +>[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea solani TaxID=1144553 RepID=A0A1H6BZH7_9ACTN +-------FEHLFRLAGVTGRIYAADLDTGHDV-GLGADDPVPTASIFKVPLLVAFCRQAD +AGLLDPTERVTVTADDRVPPTGISMMLDDVTISLRDLAYLMMAVSDNSSADKLLARV-GF +DAVDAMLKSFGLAETRVTQSAREMHEALDPAIANRSTPRETARLFGLIWRDEAASSESCA +WMRAVLNAQVW-PHRLASGFPDDVAVSGKTGTIPT-LRCEAGVVEYPDGARYAVSVFTHS +FGLNQPRADAVIGTAARMAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Microbispora sp. KK1-11 TaxID=2053005 RepID=A0A544ZAK8_9ACTN +--------ERVFRSAGVTGWLHAVDIDRGREV-GLGADQPVVLASVFKVPLLLELHRQAE +RGLLDLTERVGVPAADRTAGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLARV-GR +EAVNALLDGLGLTATRVVQNCRDMLAALDPALGNRSTPREMTRLLAMIWRDEAAGAASCA +AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +FSQNQPRADAAVGAAARMAIDQ- +>[subseq from] Beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A397WIZ3_BACVU +---LTDSISRIVSACPGEIGVAII-INNTDTV-KVNDKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVKIDRNRLDSWSPMMKDYSELVLTVRDLLRYTIAQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHDRAYFNYTSPLGAAMLMNRLFTESIVSGEKQS +FIKNTLKECVTGTDRIVAPLKERVSIAHKTGSGCNGAHNDVAYICLPNNVCYTLAIFVKD +FKGNESQASQYVAHISEVVYS-- +>[subseq from] Serine hydrolase n=2 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5RPS6_9BACT +---LNEELETLSSESKARIAVALHDLESGLRF-SLHGDRWFHAASTIKVAVLLAIFRAAD +EGRLRLDDSLHVRNRFISAGSSFHYQTIGRTAKISALAEGMIASSSNLATNLLLDFV-GV +EYARNVLRDAHVEGVELRRGVED-HAAHERDINNEATANGLLTLLSA-VRGNFLSSDSKE +QAIRILLQQRF-RSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EHDGRRETVAAISEAIFR-- +>[subseq from] Serine hydrolase n=2 Tax=Alcaligenes TaxID=507 RepID=A0A4P8JI62_ALCFA +-eRLQERLEPLLTQESARISMAVYATDGTSLF-EWHAQRVMPSASLIKTPMLLCLLEQVA +QGKLSLDTVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM +DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTVQDACSTLLYLLHSPALPESLRQ +QGLDMLADQRE-RGHFAAILPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG +FT--------------------- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus sp. 7894-2 TaxID=2021695 RepID=A0A268ILY0_9BACI +-hTLKAEILTLASSCEGRVAVCIH---TGDGViEKDADAVFSSASLIKVPILLAGLSQAE +KGMLQLEEELEVTVSARVGGSGVLQAMARDLIKVTDLMTLMIIVSDNTATNLIIELL-GI +EKINQLFKNLGFNHTSLNRKMMDFE-ALKNGIDNTTTARDMLYGIKALAEQKLLSGKYTE +KALYILENQQFKNKLANTIDEEKVTVAGKTGELP-GIEHDCAIFTHKGKA-VCAAVLVDR +LQN-QAAGKEVLSAIGSRI---- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536A8Y0_9CHLR +--------RERLSTLPGEAAAYVCDPSGRELF-SERADEPFPAASVIKLPLVMAIFADAA +RGRVDLDERVAVGE--RVDGSGVLRHMRDVELSLRDLAMLAVIVSDNTATNRLIDRI-GV +ERVNERLREWGCPNTRLARRMYDFAAA-ERGAENLMTARETASLLVRLIRGECEDRATSE +AVMALLAECQD-RTMLRRYLPNAADVANKTGTLDE-SRNDAAIVRGE--PTVVVAAFTRK +LRDTE------------------ +>[subseq from] Serine hydrolase n=1 Tax=Balneolaceae bacterium TaxID=2053516 RepID=A0A6A8QBA6_9BACT +-qHLKDRISERLEGVKGDFAVAFKNLEDTTESvYINEREMFHAASTMKTPVMIELFKQAE +AGKFSLDDSIIIKNESIVDSSLYRYSRIGEKRTIRQLINDMITVSSNLSTNILIEKV-GA +RNVSRTMRSYGADSIKVLRGVEDIK-AYQQGLSNRTTARDESIIYEKLGRGEAVSEEASE +QMIEILTNQHF-NEMIPAQLPGEVVVAHKTGWIT-GINHDAGLIILPDEQKYVLVLLSKN +AP-DREKVLAAFADISHYVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Prevotella sp. ne3005 TaxID=1761887 RepID=A0A1H8D967_9BACT +-------------------------MQNGSIV-GINEDKPFAMHSVMKFPQALCVADYLN +RKGLDLDDTIVVDKADLMQWSPMLKRFECKTFSFAELLELSLGQSDNNASELLFKHCGKP +KAVEKYMRKLGFRDIHVRMTEEQMHKRPTKAIENSSTPAEMVRLFEWFYHHKD-DNRYLT +FIWKAMADCSTGLKRIPAAITADARIVHKTGTGFLQDMNDAGIILMLDGSHAIIAVFTTN +SS-----SEAVIANITRQLLD-- +>[subseq from] N-acetylmuramoyl-L-alanine amidase n=1 Tax=Bacteroidetes bacterium HLUCCA01 TaxID=1666909 RepID=A0A0P8AUH4_9BACT +----------------LTLSVLIQAPDGTELF-AHQADRQVPSASVIKTPILVTLLQMAA +KGDIDLSETYTLTEADIVGGTGDLQHEGPGLLSWLDYARLMIKTSDNVATNVIIAKV-GM +DAVNALTTSLEMDQTVLARYMMDTK-AIEEGRQNYTSPRDMNRLLLALYHGRILDAPERA +LFWDMLKDCDD-DTMLRAGVPPQYTVANKTGILSY-VRGDSGVLFGQQ--DFIITAFAED +FN-DVSRAEQAIADVVR------ +>[subseq from] CubicO group peptidase, beta-lactamase class C family n=1 Tax=Olivibacter domesticus TaxID=407022 RepID=A0A1H7W921_9SPHI +-----KVLAAFDKQPTGTFAVAFRAIDDGETF-LLNEHQLFHAASTMKTSVLVEVFKQTE +KGKFSISDSIKVYNKSIYDGSSYTYSKIGLKVTIEDLLNRMITESSNLATNMMIDLV-GA +KNVMKTMRSIGANEMKVLRGVEDGK-AFEHNMNNMITANDLMILFDQIAQGKMISKKASD +AMVAILSKQHF-RGIIPAGLPADVKVANKTGSINK-ISHDSGIVYLPDGRKYVLILLSKG +IEE--EVAKRTLSSVSTYVYRY- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus animalis TaxID=1605 RepID=A0A062XBL9_9LACO +--------------------VYVAPMNEDVSY--LLNNQTQSAASVIKLFILAAAYAQQK +IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI +DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA +EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENEKGA-FVVVVLTQN +GDNN-EERS-------------- +>[subseq from] Beta-lactamase n=1 Tax=Tannerella sp. oral taxon BU063 isolate Cell 1/3 TaxID=1411022 RepID=W2CQD2_9BACT +------------------------IVNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Serine hydrolase n=2 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5ZV22_9BACT +---LHEELEALALKNKARIGVALHDLETGFRF-SFRGDRWFHAASTIKVAVLLALFRAAD +EGRFRLDDSLHVRNRFFSAADGSLYTAIGRTAKISSLAHAMICGSSNLATNLLLEFV-GV +EYARTVLRDAQVDGVELRRGVEDH-GAHEEGINNEATADGLLRLLSAI-RGDFLTPESKR +EVIRILLEQRF-NSMIPAGLPPHATVAHKTGEIST-ACHDIGIIYLPEREPYIAAILTEF +DP-EREGRRETVAAISEAIYR-- +>[subseq from] Uncharacterized protein n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A645CDR0_9ZZZZ +-----QKIFEILGSLEGKVSLYAEDLDSGETL-VICPEEIHVACSLIKIPILALLLKDGE +EGKVDIEAKIQIPEERRVGGTGMICHLSEGLLSWKDIMKLMIAVSDNTATNAIIDLL-GM +ERINAFFGDIGLFSTELQRKMMDLDA-VKAGRNNYTTAADMGKVLKMAASGTLVSRRASE +TVLEIMSRQFY-TNKLPAMLPAVVAVANKTGDLPK-TQHDMGYFVLPGGRKYIIAMLTSN +LS-SDQEGISCIGKVSKAVYE-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus koreensis TaxID=284581 RepID=A0A0M0LIE9_9BACI +-qDLQNTIENIVNGISGRMGVYVQL--GNEHI-NVNGDLSMPSASLIKIPILLELFHQVE +QGLIHLREINEIKDFKRVGGAGVLQSLTNDVLTWYDLAVLMITVSDNMATNALIHRL-NM +NAVNDYCHAF-TEATVLQREMMDYE-AIKKGKDNWTSARDMVKLLTLIENEQFLSRESRQ +EIYSILTKQQF-QDKLPARMDDTVTIANKTGELE-GVEHDVAIIDGYGQ-RIYVAVLTHQ +LVNS-YKGRSAISAIGYELYQ-- +>[subseq from] Serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A2U2BJD5_ALCFA +-eRLQERLEPLLTQESARISMAVYATDGTSLF-EWHAQRVMPSASLIKTPMLLCLLEQVA +QGKLSLDTVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM +DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTVQDACSTLLYLLHSPALPENLRQ +QGLDMLADQRE-RGHFAAILPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG +FT--------------------- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI00052D29A6 +-eRLQERLEPLLTQESARISMAVYATDGTSLF-EWQAQRVMPSASLIKTPMLLCLLEQVA +QGKLSLDTVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM +DNINAWSAQAGLKHTDLQRHMMDMKAR-EAGKDNWTTVQDACSTLLYLLHSPALPENLRQ +QGLDMLADQRE-RGHFAAILPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG +FT--------------------- +>[subseq from] serine hydrolase n=1 Tax=Algoriphagus resistens TaxID=1750590 RepID=UPI000716AAC3 +--QLNSTIISQLDSIKGDVAVAYINLSDPSDSlMINAEQEFHAASTMKVPVMIELFKQES +QGKFNLNDSILLKNESIVDSSLYSYSKIGTRQSLRDLMYSMITVSSNLATNVLIELV-DA +KNVTATMRELGADKIEVLRGVEDTK-AYELGMSNTTNAKDLLIVMKAIAENKAGTNKACE +EMISTLTDQKF-NTIIPFYLPETVSVAHKTGSIS-GVHHDAGIVYLPDGRSYVLVILSKN +LE-DYDTATEQLARISKTVYEY- +>[subseq from] serine hydrolase n=1 Tax=unclassified Pseudoxanthomonas TaxID=2645906 RepID=UPI0003FE1061 +--ALEPRLRAIEAALGAGIGVYVLHMERDESY-GYRAGEPWYLASGVKVPVAIAVLREVE +RGTLALDTPVVLRADDFVDGAGATNRHRPGELALSWLLEQMIVHSDNTATDVLIRTV-GL +AAVNRVAAELVDARLRIT------------------------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=unclassified Pseudoxanthomonas TaxID=2645906 RepID=UPI0003FE1061 +------------------------------------------------------------ +---------------------------------------------------------AGP +ARVRKLAALLGVPPEQLRQDLAAAFEAYYATGANSATLVDYGRMLATLADGKALGAEATG +WLLERMLRVETGHRRLRAGLPPGIAFAHKTGTQYR-RTCDLGIAMQPDPARVVVAACVRG +IG--TAAGVHALQRIAAAI---- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6HTM0_9BACT +--TLNEEVERLSAESNARIAVAAHDFESGLGF-SLRGDRWFHAASTIKVAVLLAVFRAAD +EGRLHLDDSLHVRNRFISAGSSFHHQLVGRTVKISTLAEGMIATSSNLATNLLLDFV-GV +EYARKVLRDAQVDGVELRRGVEDYA-AHERGINNEVTADGLVSLLSAV-RGDFLRNESKE +QAIRILLEQRF-NSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EGNGRREIVAAISVAIYR-- +>[subseq from] Beta-lactamase n=1 Tax=Collinsella aerofaciens TaxID=74426 RepID=A0A174A444_9ACTN +---LQQDIEALAEPYGGSTSVYAVALDLDGEV-AVAPDARRVAASIIKLPILACALETVA +AGGLSLDEQVTVAQQDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANLVIGRL-GM +DAVNETCAALGLTQTVLARLMMDAEAQ-ARGRENYTSARDAATVLQHLAAGTIATPELYE +RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD +LEREQ------------------ +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E3J1T3_9BACT +-----EELQSAIEGVQGTVGFAAKHLETGQQL-SHNADSIFFTAGTLKVPLLTELYRQVD +EGYINLSERIELSDDLRVPRSGIFKELATGLPTVRDAAMLMIIISDNTATDALMEMV-GR +ESLHDTRQTWGLLQTRIPMSVRQLLYAYDEAKSDVSSPADMSRLLELLQSGDILSPESTA +DALDILKRQQL-RTVIPHTLPIGTSAAHKTGFYL-GVRADAGIVSGPNG-PYTIAIMAKN +ITASDRVKDLSLSPISAAIYRAf +>[subseq from] serine hydrolase n=1 Tax=Gordonibacter sp. Marseille-P4307 TaxID=2161815 RepID=UPI000F5251EE +---IEALVSRSEAQFGMEVGVAYLDLSDGARF-EINGYRSQVSASMIKLLILSEFARQVD +AGTIGLDDRYVLQRSDIVGGTGSLQSRGAGAITYAELAEKMIAESDNVATNVLIDRL-GM +DAINGESQRLGLSETRLNRKMMDVAA-VSSGVENYMSAVDAMHILKLIYQNDLASPALNK +LALDALNGQTD-NRGIRDGLPEGMTFAHKTGTLS-AVQNDGGIAGG--DRPFILVVFCQS +KAGSAQAAFSLMENIANII---- +>[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Thermokryptus mobilis TaxID=1643428 RepID=A0A0S4MU31_9BACT +--EVVSKIQKVAKKYGGRLGLSAKNFVTGETI-QINADSLFPTASVIKVPILVELFYKFE +EGKLKKDTLVSLDDSLKYGGAGVLQYFYNGALKLIDVAVLMIILSDNTATNLVLDCFANL +EAVNSRMKSLGLENTKILNKLMSFKTKKNTPEAGYTTPNDMLKLLEMLANGKIINPSVSA +EIINIMKNNQD-YEMMKRYLPEKVAVANKTGSIDR-MKADIGIVYSQCT-TYAVAIFCDQ +LSAVDNKGHLAIAEISKIIFDYf +>[subseq from] Beta-lactamase n=1 Tax=Plautia stali symbiont TaxID=891974 RepID=U3TR40_9ENTR +------------------------------------------------------------ +------------------------------------------------------------ +--------EIGDNKYRLDRNEPSLNTAIPGDNRDTTTPDAMAESLNKLVLGSVLAETQRA +KLTEWMKGNTTGLNSIRAGLPSDWAVGDKTGSGDYGTTNDIAVIWPKDHAPIVLTTYFTQ +RVKDASARKDVLASAAKLVAE-- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_2_20CM_2_66_4 TaxID=1803462 RepID=A0A1Q7AFE3_9BACT +-qRLQASIERTTKSINATWGIYVKSLETSEEI-ALDADRQMETMSTIKIPLMVEAFEQMK +AGKFRLTDKYTFAQADSQPGTGIIQRLDPGALTGKDLITLMVIVSDNTATEVLYRMVGGI +DAVNRRMDAMGLKSTRAMSLPTAWFAREGKHPFGLSTPREMGRLLEMMERGTLVDKASSD +LMLQIMRGQLY-RTRIPRYVT-GYRVPHKTGDFLPFVGDDVGMLEADGR-TIVVSIFTGN +HFGSGEALENAIGLVAKEVADYy +>[subseq from] serine hydrolase n=1 Tax=Collinsella aerofaciens TaxID=74426 RepID=UPI0009E72439 +---LQQDIEALAEPYGGSTSVYAVALDLDGEV-AVAPDARRVAASIIKLPILACALETVA +AGGLSLDEQVTVAQQDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANLVIGRL-GM +DAVNETCAALGLTQTVLARLMMDAEAQ-ARGRENYTSARDAATVLQHLAAGTIATPELYE +RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD +LEREQ------------------ +>[subseq from] serine hydrolase n=2 Tax=Paenibacillus elgii TaxID=189691 RepID=UPI000FD65743 +-nQLEATIRQAASSVEGKAGIAV-DTAEGQIH--IHADEPFPSASLIKIPILLEAYRQAQ +EGRLDLHQPYAVPSGERVGGTGVIHQLSGALLSLQDLMALMIIVSDNTATNMIIDLI-GM +GTVNKLSDGLGCGATVLGRKMLDFQAK-RNEKDNFTSARDMIIFLKEIVGGSTLKQEAKD +AALQLLRNQQF-NAKLPARIIDKPVLAHKTGELP-GTEHDAGILQVNGK-TAYIAVLTTD +LV-DNLPAQQVISTIGKAVFDY- +>[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3QZJ4_9BURK +-------ARTQAEAHGLQLGVHVRDLDSGVSA-NWGGKRSWYLASMVKVPVAIAVLKAVD +DGVVTLDTQLTVRASDYVDGAGSTNASVGTPLSVRFLIEQMIIHSDNTASDMLIDLV-GL +DAINALVRQHVPEGMQRITTLAEVRRDYYAGQLNSGQLDAYGDLLAQLVQGSLLSRASTA +HLLGVMERVVTGPNRLRAGLPAHVRLAHKTGTQR-ARICDGGVARVSQQARRVLIVACVS +GAGPRVQAERALAHTAAAVC--- +>[subseq from] Beta-lactamase class A n=1 Tax=Clostridium grantii DSM 8605 TaxID=1121316 RepID=A0A1M5UDF2_9CLOT +----RKKILKIINEYGINTAIYYKNLENNKKF-TLNEKEKLPSASLIKLFIMYHAFKKVS +EESLSLEIQIPVNRNDTVEYSIIEA-LSIDKYSLEDLITLMIIQSDNTATNILINYL-GM +SNINDTINELSMQKTSLNRKMMDFYAR-ENGIDNWTSAEDVGELLYKIYKDEFRNSELNK +KIFAIMKRQIF-MTMIPRYLNESYEIFNKTGDLPN-INNDAAIIFHSQGN-SILVILTKD +CK-DKYKAQEFVGKVAKIILE-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9NDE0_9BACT +--ALQDKIAQIRSQFPGEMSIYMKNLDSGDEI-TVDSDKVFETFSVIKLTIAAELMHQVE +GGKFSLSDRIPLTAGDERLPSGVLYALDPGLPTVNDLLTLMIILSDNEATDILADKV-GR +ENITTYMHSLGLANTSIRYTDLDWDRYDAGIYFGHSTTREIGQLLEMMVGGKLVSKSSSD +RLLGIMEKQQV-NDRFPRYLK-DIRIAHKTGDGQPFIANDAGILWVNG-EPIVLVVFTGH +HRGTTTSLHDAIARIAA------ +>[subseq from] serine hydrolase n=1 Tax=Nocardia niwae TaxID=626084 RepID=UPI0007A3F8F3 +---TEDRIRAVFADAGCSGWLHARRCDGSATEvSVGGDERVVLASVYKLPLFVAFCRQVD +AGRIDPAARLTVIPSDCTPPTGIAVMRDPVTMSLRDLATSMMTVSDNAAADVLLGAA-GL +GAVESLLDDLGLDRTRVVGGTADLHRAYDPSYTSATTPEEMTRLLRALWSGTVLSAEQTD +FVRTVMRLQVW-PHRVAAGFPRSVATAGKTGTIGV-IRNEVAVVEFPGEHPVAVAVFTRA +ARADLPAVDAAIAETARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Prevotellaceae bacterium MN60 TaxID=1945887 RepID=A0A239R6N4_9BACT +-------------------------MQNGSIV-GINEDKPFAMHSVMKFPQALYVADYLS +RKGVELDDTIVVDKADLMQWSPMLKFFEGVKFSYGELLELSLEQSDNNASELLFKYCGKP +HAVENYMRELGFHDIHVRMTEEEMHKNPAKAIENSSTPTEMVRLFEWFHHHKD-DNQYLT +FIWKAMADCSTGLKRIPAAIPADARIVHKTGTGFLQDMNDAGIILMLDGSHAIIAVFTTN +SS-----SEAVIANITRQLLD-- +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea zeae TaxID=1642303 RepID=A0A5S4F2Z1_9ACTN +-------FDALFRMAGVTGWLYAADIDADRQI-GHGADEPLPIASMFKVPLMVELCRQAD +AGLLDLAARVTVTRADRVPPTGISAMLDDVTISLRDLAYLMIAVSDNSAADVLLGVV-GF +DAVNSMLAGFGLGGTHVSQSCKESNDVLDPARSNRSTPREMARLFGLIWRDEAASAESCA +WMRAVLNMQVW-PHRLASGFPDDVAVSGKTGSFPT-LRNESGVVEYPDGRRYAVAVFTRS +LSTAQPRADAVIGTAARMAVDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas argentinensis TaxID=289370 RepID=A0A1I3I420_9PSED +-eALHQRLGELENASPGKLGVYLLRPHDGSEL-NYQAERTWYLASATKAAIAIAVLQEVD +DGKLQLDQPITLEEGDRVDGSGLVWEDAGARYSVGELLREMLQESDNTAADMLIRVA-GE +ARVNERIAAAADNGF--------------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas argentinensis TaxID=289370 RepID=A0A1I3I420_9PSED +------------------------------------------------------------ +----------------------------------------------------------GP +QRVEAVANALNLQTAQLESDLDEAYRRYYASGLNSATLVAYGRLMGKLAKGELLSDASTR +LLYDIMGLDSYEAYRLEAGLSEQLPFVQKTGTQLH-RACHMGIANPQGDDALVILACAEA +LDED-VEAGKLFEQVGEAI---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Alphaproteobacteria bacterium HGW-Alphaproteobacteria-13 TaxID=2013659 RepID=A0A2N3DY97_9PROT +-----------------------------------------------------------D +QGRIPLDQPVRIGPEDLTLHQPIAVRVRSEGMPVRELIETAITHSDNSANDSLLRTVGGP +EAVRRFLARKDMGAIRFGPGERLLQAAYLADPVDGASPSAIASALTRLARGSLLSPESTE +YLLGVMTRTKSGPQRLKAGLPPGWRFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGN +TTARIPERMALMQAVSGAVAE-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=I0AXW9_9BACT +--ETLVKVKDAEHXLGARXGYIELDLNXGKILeSFRPEERFPMMSTFKVLLCGAVLSRID +VGQXQLGRRIHYSQNDLVEYSPFTDKHLTDGMTVRELCIAAITMXDNTAAKLLLTTIGGP +KELIAFLXNMGDHXTRXDRWEXELNEXIPND----------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI001232C48D +------------------------------------------------------------ +------------------------------------------------AANLLLATVGGP +AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASQRGARGIVALLGPNNKAERIVVIYLRD +TPA-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5S9N5_9BACT +---LNEELETLSSESKARIAVALHDLESGLRF-SLHGDRWFHAASTIKVAVLLAIFRAAD +EGRLRLDDSLHVRNRFISAGSSFHYQAIGRTAKISALAEGMIASSSNLATNLLLDLV-GV +EYARNVLRDAHVEGVELRRGVEDH-AAHERGINNEATANGLLTLLSA-VRGNFLSSDSKE +QAIRILLQQRF-RSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EHDGRRETVAAISEAIFR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Flavisolibacter ginsengisoli DSM 18119 TaxID=1121884 RepID=A0A1M5CEN7_9BACT +-kKLQRQVHELLQGFNGQVGVYVKNLKNGKVV-AINEDSIFPTASMVKVPILTGVMDKVN +KGELDLHQNLTYRDSLLYAGVDILGSFKDTEIELGKVVMLMLVMSDNTASLWLQSLAGTG +KRINAIMDSLGFQSTRVNSRTPGREANRAQYGWGQTTPREMATLMEKIVKGEIINKERSA +QMLRLLGRNYW-DEYAISQIPSDVFVASKGGAVDE-SRSEVLFVNGH-GARYVFCINTKN +IKAKSNEAWELTRKLSKLLWDHf +>[subseq from] hypothetical protein n=1 Tax=Acidisphaera sp. L21 TaxID=1641851 RepID=UPI00131C1357 +---------------GVTIGVAALA-PAGEPF-AYHGSRRFVAASTVKIAIMVELFRRID +AGRITLEQRHILREDEKAGGSGVVSNHTGIEMTIRDLVYLMMSVSDNSSTNILIDAL-GI +EAINATMCDIGMQHSTLGRKMRGRHLV-ASEAENWAVPEDYVTVIKSILDGHAASSESCA +QMVALLEKQQN-DRRIARHLPNRPRWGTKTGSLP-GVVNDVGFIMTGRG-PLILAVFCEG +LT-DGPTGEQIVGDIAKAALD-- +>[subseq from] serine hydrolase n=1 Tax=unclassified Nocardia TaxID=2637762 RepID=UPI00135745D1 +---AQDRIRAVFADAGCSGWLHARRCDGSATEiSVGGDERVVLASVYKLPLFVAFCRLVD +TGRIDPAARLTVAPSDCTPPTGIAVMRDPVTMSLRDLATSMMTVSDNAAADVLLGAT-GL +GAVEGLLDDLGLTRTRIVGGTADLHRAYDPAYTSATTPEEMTRLLRALWSGAVLSDEQTE +FVRTVMRHQVW-PHRVTAGFPRSVSVAGKTGTIGV-IRNEVAVVEFPGEHPVAVAIFTRA +ARADLPVVDAAIAETARIAVT-- +>[subseq from] DUF3471 domain-containing protein n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A4Q5S9F0_9BACT +------VLDAFAEHPAGKFAVAFKDLKTGTSL-LINERDQFHAASTMKTPVLIETFKQAA +AGKFNISDPILIRNESIVDSSLYSYTKLNTKLPLYEVLHRMITRSSNLATNLVIDLI-GA +ENANATMRSLGAHDIQVLRGVED-NKAFAKGLNNSTTAYDLMIIMDALATGKAVNTKASE +EMIKILMDQKH-LDKIARKLPPGVKVASKSGSIT-AVSHDSGIIYLPDGRKYVLVLLSSG +VQ-SYDDVNNTLANVSKMFYD-- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus infantis TaxID=324767 RepID=A0A5D4R4K8_9BACI +-nQLEQRLADILRQCPGNASLAVEY--GEMAI-YMNSGRTYPAASLIKIPIMMEAFFQAE +AGALDLNEQVRIGGIEKSGGAGIIQSSVKASLSILDCITLMIIVSDNTAANLLIKLL-GK +KNINDRMHGLGLQTTVLGRKMMDFEAA-AKGIENFTTAADMVKCLRAIKDGELFSEKNRS +RMLDIMEAQQF-REKLPAIACKDLKIANKTGELP-GIEHDCAIFTS-GRDDLYAAVLIDS +LS-SPEEGKHAIRQIGS------ +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes aquatilis TaxID=323284 RepID=UPI000D52B55D +-eRLQERLEPLLTQESARISMAVYATDGTSLF-DWHAQRVMPSASLIKTPMLLCLLEQVA +QGKLSLESVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM +DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTAQDACLTLLYLLHSPALPENLRQ +QGLDMLADQRE-RGHFAAMLPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG +FT--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6JHC9_9BACT +---LHEELEALALKNKARIGVALHDLETGFRF-SFRGDRWFHAASTIKVAVLLALFRAAD +EGRFRLDDSLHVPNRFFSAADGSLYAAIGRTAKISSLAHAMICGSSNLATNLLLEFV-GV +EYARTVLRDAQVDGVELRRGVEDH-GAHEQGINNEATADGLLRLLSAI-RGDFLTPESKR +EVIRILLEQRF-NSMIPAGLPPHATVAHKTGEIST-ACHDIGIIYLPEREPYIAAILTEF +DP-EREGRRETVAAISQAIYR-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7RVQ6_9BACT +--TLEETIRARLDSLQAQSSFYAKQLASGHEV-SIRADVPMNTASVIKIPVMILAFRDAD +AGRLDLDQRYVIRPEDQRRGSGLLQTFAPGIPTLRDIVTQMIITSDNTATDIMIAKV-GR +DRVNRMLDSLGYRQTRLNATTGDLFRADSSKWLGKTTAREIGRLLEQLQRGDLASKASTQ +EMLRILRQQFY-ASRLPQRIRFRAGIAHKTGDWPPLLGNDVGIIYAPSG-PIVAAVFTNM +NRGDFTDLEATEGRIGEDLLNA- +>[subseq from] Serine hydrolase n=1 Tax=Ammoniphilus sp. CFH 90114 TaxID=2493665 RepID=A0A4Q1SPQ9_9BACL +-----SVLLNIIEDAGGTWGIVAEDLNHQLRL-EYGEQVSFTAESIIKIPIMAAVFAEVE +KQQLSLSDLVLLKREDLVGGSGVLQHLSPGILPVYDLLMLMIIQSDNTATNLLIDLV-GT +KQVQQTMADLEMLDSQFHRKLMVYPAE--IVEKNRITAADVSLLLKKLATGSFLSHKACQ +QMINILKKQQI-RNGLPAYLSAHWQLANKTGWDT-GAQHDVGIFYIGQR-TMTITVLSKD +VD--AIVALDAIARIGREIYHY- +>[subseq from] serine hydrolase n=1 Tax=Paenibacillus elgii TaxID=189691 RepID=UPI0013D106A4 +-nQLEATIRQAASSVEGKAGIAV-DTAEGQIH--IHADEPFPSASLIKIPILLEAYRQAQ +EGRLDLHQPYAIPSGERVGGTGVIHQLSGALLSLQDLMALMIIVSDNTATNMIIDLI-GM +GTVNKLSDGLGCGATVLGRKMLDFQAK-RNGKDNFTSARDMIIFLKEIVGGSTLKQEAKD +AALRLLRNQQF-NAKLPARIIDKPVLAHKTGELP-GTEHDAGILQVNGK-TAYIAVLTTD +LV-DNLPAQQVISTIGKAVFDY- +>[subseq from] Beta-lactamase class A n=2 Tax=Imperialibacter sp. EC-SDR9 TaxID=2038371 RepID=A0A5E8A4D2_9BACT +-nELKQSIAAAFEANTGDYAIAFKDLSNPDNQlYINEKETFHAASTMKTPVMIELFRQAR +AGKFSLSDSILVVNESIVDSSAYTYSFIGQKLTIYDLTYEMITVSSNLATNILIELV-GA +PNVMTTMKSFGANDIQVLRGVEDQK-AYELGMNNTTTAKDLAIVMEMIATDKAGTPEDCA +AMIKILKDQRF-NDIIPTYLPDSVSVAHKTGSITK-LHHDSGIVYLPDGRKYVLVLLSKN +LN-TIEEGTEVLARVSEKIYSY- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonas sp. SM23_52 TaxID=1703359 RepID=A0A0S8H3F2_9BACT +--SLEERVRARLDSLDARTSLYAKHLPSGREI-AVRADQPMNALSVIKIPIMLLAYRDAA +AGRLDLDERYRIRPEDMRRGSGLLQTFAPGLPTYRGLVTQMIITSDNSATDIMIERL-GL +ERVNEMLAELGYEETRLRTTTGQLFRALEGDSTQWTTAREIARLLEGIHNARLASPESSQ +EMIRILRRQFY-SSRLPQRIRFQAAVAHKTGDWPPYAGNDVGILYYEGG-PTVVAVFTNQ +NRGDFFELEATIGRIAEDLIS-- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus versmoldensis DSM 14857 = KCTC 3814 TaxID=1423815 RepID=A0A0R1SLG1_9LACO +-------------ESDGQTSAYFYDLNSDQHA-QYGDDSTQRAASNIKLFIMAAAYQKVK +DGELDLSDHYTLKDSDKVGGTGVVQQMETGSISYHDLIKDMITQSDNTAANIMVDTIGGL +DVVNDEISDLGLSDTTMERKLMDTEK-LEAGHDNMTTAHDLGIFMKKLYNHQVVSKTYDE +DMLGILKDTSN-HSKLPSQVASDITVYNKTGEYNYGVQNDVAIFQKGDKA-FVISVMSED +GTESDQ--KE------------- +>[subseq from] serine hydrolase n=1 Tax=Nocardia beijingensis TaxID=95162 RepID=UPI000832923D +---AEDRIRAVFADAGCSGWLHARRCDGSATEiSVGGDERVVLASVYKLPLFVAFCRHVD +AGRIDPATRLTVVPSDCTPPTGIAVLRDPVTMSLRDLATSMMTVSDNAAADVLLGAT-GL +GAVESLLDDLGLERTRIVGGTADLHRAYDPSYTSATTPEEMTRLLRALWNGTVLSAEQTG +FVRAVMRLQVW-PHRVAAGFPRNVSIAGKTGTIGV-IRNEVAVVEFPGEHPVAVAVFTRA +ARADLPAVDAAIAETARIAVT-- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacterium sp. TaxID=1872119 RepID=A0A2G4JM23_9BACT +----TQLLESHLAGFPARTGLYVKHLGTGEEA-AVRGDESFSSASVIKLAIMIRAFQLVD +AKTLDLNARVTIGRADLRDGSGVLQYHDLGLPTYRDLITEMVITSDNTATDLMVQKIGGV +EALNKWLMASGFTHTQMV------------------------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q6UIV7_STAAU +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSQKDTSTPAAFG------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2E4P453_9BACT +---LEKKIIETLNSQKGDFSVAFKNLSNKXTI-LINENEEFHAASTMKTPVMIEVFKKAQ +KGIISLDDSIKIKNESIADGSTFKYDKIGSYLSLRELVFDMITISSNFATNLVIDYI-GS +DNINNTMRDLGAKNINVLRGVEDIKA-FNQGMNNTTTALDLLKIYENLAVGNVINSEISK +EMVEILKKQKY-DDIIPKYLPKSIEVAHKDGWIN-GVRHDSGIVFLEDNTTYLLVLLSKN +LE-DEIKGADLLAKVSLEIYN-- +>[subseq from] Serine hydrolase n=1 Tax=Xanthomonadaceae bacterium NML93-0399 TaxID=2032565 RepID=A0A2A3LNF6_9GAMM +-dALARRLAAVDAAYPGEIGVYVHHVGRDESW-GLRANESWYLASGVKVPIAIAVMREIE +QGWLTLDTEVTLLETDFVDGAGRTNAHRAGDLTIAWLLDQMIVYSDNTASDVLIRTV-GL +GQVNAVAAELIASQGVHITTLADVRRSYYATHVNSATLGDYGRMLVALQQGLALDAEHTA +YLLGVMSRVKTGQRRIRAGLQPTADFAHKTGTQYR-RLCDSGIVTMPAGPPVVVAACVRG +PT--GATGERALRSIGEAVT--- +>[subseq from] Serine hydrolase n=1 Tax=Caenimonas sp. HX-9-20 TaxID=2596921 RepID=A0A562ZFB8_9BURK +------------DANASAIAVATYDFMHHTAW-SLNPERWFHAASTIKVPVLVAVYDAIE +QGRFEPHSRVHVRNRSVVDGRPFREVHAAIGLTVHELAEHMIVTSSNLATNLLLDLV-GI +EAARASLARLRLGGIDLLRGVEDE-LAWEAGLNNRVTAAGLCAALRMIDEGQAISKDACK +AMLDILHQQRF-RTGIPAGLPEDARVAHKTGEIST-VAHDAGIVYLDGRDAYVVVILTEW +AP-EVNGRQETIARISRAVYE-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Omnitrophica bacterium CG11_big_fil_rev_8_21_14_0_20_41_12 TaxID=1974745 RepID=A0A2H0M3M2_9BACT +---LNDDLKSKIASFKGKVALVVEDLNTGWVI-SFNENILMPSASLVKIPIMLSCYYAQQ +EGRINLKGSLRLKSFQKVSGSKVLGDSPVGSFVIEELFDPMITLSDNSAANVLIGLM-GF +NDWNMYFKKMGLKNTNIVRNMMDFRSR-RRGRENYTTAVDMAYILEKLYRRQFLSQEISE +KCLILLSQQKI-NDRIPRKLPQDILAVHKTGLERH-ICHDVGIVYTRKGN-FLICVLVKH +ENKFAQPAKKLISEIALSIYNYy +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. CAG:1060_57_27 TaxID=1896975 RepID=A0A1Q6FRW7_9BACE +--SLYAAIDSLSSGLDARVGVAAV-FDGGDTL-VYDSRAEYPLMSVMKFHQALAVCDSLR +RAGIPLSRGLDVCPGQLHEWSPMRDGHPSGGFSFAQLLEYTLVQSDNNACDILFDYLGEP +AAVDAYLRSFGVGDCSIECTEDMMHKDLSLCYRNASTPLSAVLLLEKFYLLRG-SDPYYR +FLWDTMTACGTGTMRIPRFISKAAAIAHKTGTGDRDSINDIGVVVLPDGRHFSLAVFVSD +AAVPDALCEELIAEIARLAYEH- +>[subseq from] serine hydrolase n=1 Tax=Nocardia exalbida TaxID=290231 RepID=UPI00031C9C03 +---TEDRIRAVFADAGCSGRLHARRCDSATEI-SVGGDERVVLASVYKLPLFVAFCRLVD +AGRIDPAARLTVAPSECTPPTGIAVMRDPVTMSLRDLATSMMTVSDNAAADVLLGAT-GL +GAVEGLLDDLGLTRTRIVGGTADLHRAYDPSYTSATTPEEMTRLLRALWSGAVLSDEQTE +FVRTVMRHQVW-PHRVTAGFPRSVSVAGKTGTIGV-IRNEVAVVEFPGEHPVAVAIFTRA +ARADLPVVDAAIAETARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5SHR4_9BACT +---LNEELETLSSESKARIAVALHDLESGLRF-SLHGDRWFHAASTIKVAVLLAIFRAAD +EGRLRLDDSLHVRNRFISAADGCSYQAIGRTAKISALAEGMIASSSNLATNLLLDFV-GV +EYARHVLRDAHVEGVELRRGVED-HAAHERDINNEATANGLLTLLSA-VRGNFLSSDSKE +QAIRILLQQRF-RSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EHDGRRETVAAISEAIFR-- +>[subseq from] Serine hydrolase n=2 Tax=Collinsella sp. AM36-4AA TaxID=2292317 RepID=A0A396A7R4_9ACTN +---LQQDIEALVEPYGGSTSVYAVALDSQTEV-AVAPDARRVAASIIKLSILACALETVT +AGELSLDEQITVTQRDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANLVIGRL-GM +DTVNETCAALGLTQTVLARLMMDAEAQ-AQGRENYTSARDAAAVLQRLAAGTIATPELCE +RARGYLLAQED-ARGIVEGVFSGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD +LE--REQALALERDISSAIYA-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia testacea TaxID=248551 RepID=UPI00030FB899 +----AERIRAIFADAGCTGRLHARRCDSDEEV-CIGGTERVVTASVYKLPLLLAYCRAVD +AGRLDPLARLTLTPSECTPPTGISALHDPVTMSRRDLATSMMTVSDNAAADLLLGEV-GL +TAVHELLESLGLDRTRLVGGTADIHRAYDPAYTSATTPAEMTRLLAALWRGEVVSTEQTD +FARAVMRRQVW-PHRIAAGFPRGVAVAGKTGTIGI-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLPAVDAAIAEGARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Calorimonas adulescens TaxID=2606906 RepID=A0A5D8QCJ5_9THEO +-----EDIEKYIQDSDIDASIYIKSMRGDFEF-KHKETRVMPSASLIKLPMMACIYDLAY +DDRLDMEQKLKPRREQIVAGSGVIKDHADIEYSIRDLTYLMITVSDNTAANILIDYL-GM +DRINDEIEKLGMKDTVLRRYMMDSAA-RAAGIENLTTVLDMGLFFEKLYDGDVVNYLASR +EMTDILKAQRF--NVMDYYLPKRYKVAHKTGSLE-GYEHDCGIIFSQEDD-VIVCVMTSG +FKND-YEGIDYIKGLAKIIV--- +>[subseq from] Uncharacterized protein n=1 Tax=Bdellovibrionales bacterium RIFOXYD1_FULL_55_31 TaxID=1797404 RepID=A0A1F3XV12_9PROT +------------------------------------------------------------ +---------------------------------------------------------GTR +ARLRALMRKLGLRRAQLGASIDEAFERYYARGYNSGSLEGFGTVLEKLVRRELLSPAHTE +LLLGYMEQIQTGDHRIKAGIPKTVRFAQKTGTQVR-RLCNVGVMLPSGSSEAVLIAACVE +KYSDFKEAEKALQKVGRAIS--- +>[subseq from] Possible beta-lactamase class A n=1 Tax=Lactobacillus otakiensis DSM 19908 = JCM 15040 TaxID=1423780 RepID=S4NQK6_9LACO +--QIKTALKACVTNASGKTAGYVKQIGDHQPV-EFSGNRRQRSASVIKIFVMIEAFRQIK +AGTLRLSDSISIPQSDKVGGTGVLANQNTQHLTCGQLLNLMIKNSDNTATNVLIDKLGGL +GPINQSIKKLGCSNTSLQRKMLDYS-ALQSGRDNYTSASDVGKTLNMIYTHRLLGSGWDT +KMLNLLQGNAN-QTKIPAQIKNSATIYNKTGEFDYGVQNDAAIIQKGNRA-FIAVILSEN +GTQSS------------------ +>[subseq from] Serine hydrolase n=1 Tax=SAR202 cluster bacterium TaxID=2030829 RepID=A0A641AEW7_9CHLR +-qQLENTLKTKIDEFDGVAGVSLKSFSSGKHI-SINGDEIFPTASTIKIHILAKLFYLEE +KGEIDLSERIRFTQDKYGGGSGVIHFLENDPFTVLDVAILMMLASDNTATNMCIDIA-GI +ESINDLIQDMGLPETKLRRKMMDPE-AIDRGDENVSTPNELVMMMNQLHNGKPTSKVSS- +QVLRIMSKPKS--AYLNKAIGSEVTVANKPGGMDK-VRGDTGIVYLPNN-PYTVSIMSKF +SMVDSLSQEGFIIDLARTIHR-- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=Luteitalea pratensis TaxID=1855912 RepID=A0A143PYZ7_9BACT +---FSRRLDEVASSVDGSVAYLVVDVTSGQRF-ARRADEPFPTASAIKIGILYELFVQVD +AGREVLDDPKPLPEASRAGGSGIINRLRSPVLSLRDHALLMILLSDNTSTNVLIDTL-GM +DAINAHMQALGTSGYRLRRRMMDSAAAARG-DENVASASDLVTVMDAIRTGRGLRPESQA +EAIRILREY--GPTSVRAGIPADVPVATKPGGLD-GVRSEVSWVDVKGR-PYLLCVMTSF +LA-DDQAGEKAITEISRTSYQYf +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium GWC2_71_9 TaxID=1798310 RepID=A0A1G0L758_9BACT +---------RIAAQPGATVGLYYRSLVAPDSM-AIGADIRFHAASTMKVAVMIQAFRDID +SARLRLDERLPVVNASIADGSTYEYALVGRTAPVRQLVELMITISSNLATNVLIERV-GA +ARVQATLRELGTDSMVVLRGVEDGA-AYRAGLNNTTTARDLAILLEAIADGRAASAASCG +RMLQILLHQRI-NDAIPRGLPRRTPVAHKTGGLT-GQYHDAAIVYTRRRPQYVLVVLTRG +IA-QHEAATQLIADLAGII---- +>[subseq from] serine hydrolase n=1 Tax=Gemmatimonas phototrophica TaxID=1379270 RepID=UPI0006A6B5DA +---LTRLLEADLARYPATAGVYVKNLRTGEEA-MVNADQSFSSASVIKIPIMIRAFQLAD +QHTLMLDERVEITRAELRDGTGVFQFLDMGLPTVKDLITQMIITSDNTATDLMTTRVGGV +ERLNAWLAASGYSRTRMVNRGHE------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Alcaligenes aquatilis TaxID=323284 RepID=A0A3G2HZA0_9BURK +-eRLQERLEPLLTQESARISMAVYATDGTSLF-DWHAQRVMPSASLIKTPMLLCLLEQVA +QGKLSLESVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM +DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTAQDACSALLYLLHSPALPENLRQ +QGLDMLADQRE-RGHFAAMLPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG +FT--------------------- +>[subseq from] serine hydrolase n=1 Tax=Sphingobacterium sp. (strain 21) TaxID=743722 RepID=UPI0012F957CF +----KRKIEKVQKGNPGTFAIAFKDLSDNDTF-FYNEHQLFHAASTMKTPVLAETFRQIE +RGKLALSDSVEVYNESIYDGSSYAYSLIGKKATLADLLLRMITQSSNLATNIVIDLV-GA +KNVMKTMERLGAKEMKILRGVEDSKA-FAHGMNNMVSAYDLSLLFVQLARGEMINSRSSE +QMLDILMKQHF-RGIIPAELPADVKVANKTGSINK-VCHDSGIVFLPDGRKYVLILLSMG +VD--EKLAQQYLAEISGVFYHY- +>[subseq from] serine hydrolase n=1 Tax=Nocardia grenadensis TaxID=931537 RepID=UPI0007A42EC5 +----AERIRAVFADAGCTGRLHARRCDSDAEV-SIGGTERVVTASVYKLPLLLAYCRAVD +AGRLDPLARLTLVPGECTPPTGISALHDPVTMSRRDLATSMMTVSDNAAADLLLGEI-GL +AAVHELVESLGLDLTRLVGGTADIQRAYDPAYTSATTPEEMTRLLAALWRGEVLSGEQTD +FARAVMRRQVW-PHRIAAGFPRGVSVAGKTGTIGI-IRNEVAVVEFPGEHPVAVAVFTRA +ARADLPAVDAAIAEAARIAVT-- +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6LLQ5_9BACT +---LHEELETLALRNKARIGVALHDLETGFRF-SLCGDRWFHAASTIKVAVLLAVFRAAD +EGRLRLDDSLHVRNRFFSAGSLFRYATIGRTAKISALAHAMICGSSNLATNLLLDFL-GV +EYARTVLREAQVDGVELRRGVEDH-SAHEQGINNEATADGLLKLLSAI-RGDFLTPESKR +EVIRVLLEQRF-NSMIPAGLPPHATVAHKTGEIST-ACHDIGIVYLPEREPYIAAILTEF +DP-DTEGRRETVAAISEAIYR-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium sp. (strain 21) TaxID=743722 RepID=F4C695_SPHS2 +----KRKIEKVQKGNPGTFAIAFKDLSDNDTF-FYNEHQLFHAASTMKTPVLAETFRQIE +RGKLALSDSVEVYNESIYDGSSYAYSLIGKKATLADLLLRMITQSSNLATNIVIDLV-GA +KNVMKTMERLGAKEMKILRGVEDSKA-FAHGMNNMVSAYDLSLLFVQLARGEMINSRSSE +QMLDILMKQHF-RGIIPAELPADVKVANKTGSINK-VCHDSGIVFLPDGRKYVLILLSMG +VD--EKLAQQYLAEISGVFYHY- +>[subseq from] hypothetical protein n=1 Tax=Collinsella aerofaciens TaxID=74426 RepID=UPI0012E8CB88 +---LQQDIEALVEPYGGSTSVYAVALDFNGEV-AVAPDVRRVAASIIKLPILACALETAT +AGELSLDEQIMVTQQDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANLVIGRL-GM +DTVNETCAALGLTKTALARLMMDVEAQ-AQGRENYTSARDAAAVLQRLAAGTIATPALCE +RARGYLLAQED-ACGIVEGVPGGVLVAHKTGSLAD-AQHDVAIVYAE--RPYVLAILTQD +LEREQ------------------ +>[subseq from] class A beta-lactamase n=1 Tax=Asaia platycodi TaxID=610243 RepID=UPI000470A12E +------------------------------------------------------------ +-------------------------------LSLAALCAGAVTMSDNVCANMLLRHIGGP +AALTRFWRDSGDDVTRLDAFEPELNRPSADPQANTTSPVAMARTLHRLIHGTLLHPHSAA +LLRGWMISCTTGTHRLRAGLPPHWIAGDKTGNNGKDISADIAFATLEAQRSIIMTAYTSG +GTPDEARFRKVFHDIGALA---- +>[subseq from] serine hydrolase n=1 Tax=Nocardia pneumoniae TaxID=228601 RepID=UPI000A06F8A5 +--SAEERIRAVFADAGCTGWLHARRCDSAAEI-SIGGRERVVVASVYKLPLFVAFCRCVD +AGRIDPTARLTVTPSDCTPPTGIAVMRDPVTMSLRDLATSMMTVSDNAAADVLLGAT-GL +GAVEELLDQLGLTQTRIVGGTADLHRAYDPSYTSATTPEEMTRFLRALWSGSVLSAEQTE +FVRGVMRCQVW-PHRIAAAFPRSVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA +ARSDLPVVDAAIAETARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Globicatella sulfidifaciens DSM 15739 TaxID=1121925 RepID=A0A1T4LH38_9LACT +---------------------QALDHKTSSQP-LILNNQPMRSASIIKLFVLAALFEQVE +KGEMDLTEQYVLKAEDKVSGTGDIQNMQDGTLTLLTLAEKMIIISDNTATNILINLIGGI +EKVQNIIVELGYSDVQLKRLMVDLES-LKAGEDNYVTVEDVGRILADIYQEKLVSKSASQ +KMLAVLKQQTD-RQMLARNLPSDVTYYGKTGNFDYGVQNDAAIIETPNGA-FILVFLSQE +GQ--KEQQLKAMNKLGKVVSELf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC60_STAAU +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVS +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIEFNYYSPKSKKDTSTPAAFG------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase AST-1 n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A645ARD5_9ZZZZ +----AEAVQKETEAFRGTTGVVVSSLADGRRL-SHNADRVFSSASLIKLGVLYTLFSKHA +SGEIDLDEVYGFSSAECADGGLLHRVRSGARLRLDDLALLMISVSDNTAANLLIDRL-GM +DAVNGGFRELGLSGTVLGRKMLDFEAK-KAGKDNFTTAGDMAVLLETLHSGQNFPASARS +RMMEMLSLQKL-NSKLPGLIPVEQFLAHKTGELP-GNEHDAGVFFFRGRKPVVVSVLTEG +LK-DRSEGVEFCARIGRILYDAf +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus oceanisediminis 2691 TaxID=1196031 RepID=A0A160M662_9BACI +---IKAEILDLASCCEGRVAVYIHT--EDGVI-ETNADDVISSASLIKVPILLAGLSQAE +NALLDLDEEAEVKDAARVGGAGVLQAMSKGLMKVIDLMTLMVIVSDNTATNLIIERL-GI +EKINQFIKSLGFNCTELNRKMMDFE-ALKNGMDNTTTARDMVYGMKALAENSLLSGKFTE +KALDILEKQQYKNKLANTMDTEKVKVASKTGELP-GIEHDCAIFTHKGN-TVYAAVLVDQ +LQ-SQAAGREVLSAIGSR----- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7W665_9BACT +----------IKDEHALRLGISFYDAETTVQW-SYNADAWFHAASTMKLAVLLGVFREVD +RGELALDAPVHVRNRSIVNQEAFMYGHLGKTLSVKELAYWMITKSSNLATNLLVDVI-GI +PTIQLALDELEIHGIKVLRGVEDQ-RAFAAGLNNEVTAHGLLKMLRLIAEGTAYSQEACD +EMLDILLDQQY-RSGIPAGLPKAARVAHKTGNIST-VHHDAGIVYLEGRKPYVLVILTQF +PAE--QGRGTAVAEVSRDIFN-- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI0007625832 +--TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN +EVKLNLNDKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM +DKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN +AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD +GSRDEQ----------------- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=Sphingobacterium thalpophilum TaxID=259 RepID=A0A4U9VA44_9SPHI +-kRLESQIKQLIQGFQGDVGIYVHHLKKHKEV-NIQADSIFPTASVVKIPILVGVFDKIE +KGQLQLDQEFIYRESQKYGGSGLMQFFKDSTVDLKTLVGLMLSYSDNVTSIWNQKLAGGG +VAINSLMEGLQLTHTRVNSQTEGRKADWEKYGWGQTTPKEMADLVTLIREGRVISAKASD +RMYRFLGNMFY-DERGLSQIPATVKAASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN +NKGKNNEAEELTRKLSKLLWEYy +>[subseq from] zinc_ribbon_2 domain-containing protein n=1 Tax=Trichococcus flocculiformis TaxID=82803 RepID=A0A181ZN37_9LACT +-----SIIENAYSPIMGTFSAYVSRIGNENEV--VVNEQPQRAASTIKLFIMLTTYSKAN +ANELDLDSIHRLYEDEKVGGTGIIQDMPGGSLTIRELIRLMIVESDNTAANIMIDELGGF +ESINQMISKMGCYNTALNRKMMDTNA-LESGIDNYTSAKDLGVIMKKLYMNTLISEEYDN +EMLSILSHNTD-HSKLPYHLPYGATVFNKTGTYSYGVENDVAIIANENGA-FVVSVMTQD +GSA-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5XTV1_9BACT +--TLRERVERLTAESKARTAVSVHDLESGFRF-SLRGNRWFHAASTIKVAVLLALFRAVD +NGRVRLDDSLHVRNRFFSAGSPFQYQAIGRTAKISMLAEGMISASSNLATNLLLGFL-GV +EYARNVLREAQVDGVELRRGVEDH-AAHEKGINNEATADGLITLLSAL-RGDFLRSESKE +QAIGILLEQRF-NSMIPAGLPPHAAVAHKTGEIST-ACHDMGIIYLPEREPYIAVILTEF +DS-EKEGRRETVAAISQAIYQ-- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000F0BC7E0 +-eRLQERLEPLLTQESARISMAVYATDGTSLF-DWHAQRVMPSASLIKTPMLLCLLEQVA +QGKLSLESVYPLPEGERTPGTGILSQLPGVPLSLRELALLMIILSDNVATNVLIDLL-GM +DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTAQDACLTLLYLLHSPALPENLRQ +QGLDMLADQRE-RGHFAAMLPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG +FT--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Nonomuraea gerenzanensis TaxID=93944 RepID=A0A1M4E0Z5_9ACTN +------AFEQLFRAAGVTGWLYAADIDTGHDL-GHGADEPMPTASMFKVPLLVALCRQAD +AGLLDLTERVTVTAADRVSPTGISSMLDDVTISLRDLAYLMIALSDNTAADKLLGRV-GL +DVIGAMLEGFGLARTRVVQGSGEMLGVLDPARTNRSTAREMARLFGMIWRDEAASPASCA +WMRGVLNMQVW-PHRMASGFPDDVAVSGKTGTMPT-LRCETGVVEYPDGGRYAVSVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] SLH domain-containing protein n=1 Tax=Paenibacillus rhizosphaerae TaxID=297318 RepID=A0A1R1EPP7_9BACL +-----------AEKDGIRMSVGIRDLSGHETL-LLGSREPYMPASTIKLAVVSALMKQVD +RGELSLADQVRVTPEDVVGGSGSLQTSFPQDLTLERLARLMITQSDNTATNVLIDKV-GM +DRVQQLMDQLDLRTMHLGRKMFAAA--PSPAQDNYIDAADLTELLGQIYQGSFLSVSSRN +QIIAWMARQEV-NTKFGAALP-DAPIAHKTGENAN-VTHDAGYFLVPGHE-LAVSVLLQV +TTEAQRIGNPIVQQAARAIYS-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535E6J3_9CHLR +---LARQVRCLEDEFSGVLGLWAHDLRRRRTY-ELRAGEPFPAASTIKLFILHELLRQAE +AGRLSLADEVVMGRTDVVPGSGVLKDLSPGVLSLRDAATLMVTVSDNVASNLLIGRL-GV +GAINQGARACGCLQTRLGGKLFRTR--APG---STTTPRDLARLMLGIARRRAVSPTASS +LMLDILRREQS-DLIVGRLLPEEWTVASKHGSLP-GVRNDVAYVRGRTG-RYVIALMSRD +CADPDNEAVLCLARVARAVHDH- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7QEU1_9BACT +--TLRQRLDARIARAPARVGLYYRSLARADSI-LIGANLRFHAASTMKLPVMIQIFRDAD +AGLLGLDDSLTVHTASLVEGAFVVYALVGRNRAVRDLLERMITRSSNLATNILIERV-GA +ARAQASARSLGAWSMQVLRGVEDGA-AYRAGLNNTTTARDLGVLLEAIATRRAASGAACD +SMLAILGRQEF-NEGIPVGVPPGTRVAHKTGWIGEVVYHDAAVVFPPDGGGYVLVVLTGG +IKED-SVAHNLVADLSRLVY--- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A3B8ZGQ3_9PLAN +---LGSKIAPLVQSHAGQVSVAVKHLTSGAEY-FLDADRPMPTASLIKFPVMVEAYRQRA +AGLVDFSAPIQVTEADKVPGSGIITDHFADLLSLRDAVQLMIAFSDNTATNLVIDKI-GI +ASTGQSMEQLGFPNTKIYARVFRHDTSIDPERSGSTTAREMILLYEQLEKGQLVSPEACQ +EMKKHLLACDD-NTKLKKLLPLGTKVAHKTGAVS-AVRTDSGLIYTPSG-PIAVCVLTSE +NKDQSWQD--------------- +>[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001158FEF1 +------------------------------------------------------------ +----------------------------------------------------LLTTIRGP +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQI----------- +>[subseq from] Uncharacterized protein n=1 Tax=Euryarchaeota archaeon RBG_13_57_23 TaxID=1797977 RepID=A0A1F9YY88_9EURY +--KLRSEIHKIAKDVKGQFGLYLKHLESGKEM-AIDADKIFPLGSVFKIPVMMEVYRQAS +EGLVSLDEKLKLEPRYYCIGSGILQYLSPGLLTVRDLITLMIIATDNTASEMLWKRV-GI +QRVNMLMRELGLHKTSI------------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter sp. 24 TaxID=2183986 RepID=A0A4R6FVP7_9FLAO +-eELQEQITNIFKRNQGEFAIAFKNLSKKNDSiLIQEKKDFHAASTMKTPVMIEVFKQAS +EGKFSLQDSLTIKNESILDGSSYSYALIGNKRSIENLTVDMIINSSNLATNILIELV-DA +KNVNKTMKNLGATNINVLRGVEDIK-AYEAGLSNTTTAYDLMLIFEALAKGIAVSPVCDQ +KMLDILYRQKH-TDVIPALLPENLKIANKTGWIT-GVHHDSALVELPDGKQYVLVLLSKN +ME-NMQAGTKMLSEISKMIYDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptosporangium canum TaxID=324952 RepID=A0A1I3F842_9ACTN +-----------FRAAGVTGFLHAVDLDTGAEV-AHGADEPVVMASVFKLALLVEFFRQAD +AGRLDVTERITVMADRHTPPTGVSAMADDVTMSLRDLAYLMIAVSDNTAADTLVGRV-GL +SAVNTMLAAEGLDGTWVEHDCRSLFAALDPARTSRSTPRDMTRLLGMVWRDEAASAASCA +SMRRLLGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRS +TAQNQPRADAVIGTAARAAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Alphaproteobacteria bacterium 33-17 TaxID=1895704 RepID=A0A1Q3P861_9PROT +--------KHLEDNFKIRIGFHAMDLDSGRSI-GYRNNESFIMASTVKVPVSIYLMNQVD +EGNIDLAKMIYIDKSDLVPGSGKIGYFLTHDISNANLLELMMAISDNTATDLIIRQL-GM +NNIAKFFNSY--PDISLKHNIMQLFDDFYYNKADRTTPKAMALILKDFMDGKFTSIKSRD +FLLKVMSHTENKDRLKKEVLHSSDFIHHKTGTFDYYSIADVGIVKLKSCKKIIISLYLDS +VDLNAKDLEQVLSIAARIITDYf +>[subseq from] serine hydrolase n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=UPI0011E92FA8 +---LEEKILDAIDKCKGRISVAI-DLPS-HSI-QINSDTPYSAASLIKVPILLEGYRQSE +HGKIDLDETVMVPNEYRVGGAGVLSTLSERILTVEDLLTLMIIVSDNTATNLIIDRL-GT +EAINNLCNSLALKHTKLIRKMMDFQA-MKQGYDNFTSASDIITCLRSLDQGTLFNQQSRD +KMLYMLHQQQF-NTKLPARMDEKIYIANKTGELP-GVEHACAIVRSEEKT-AYIVVLIDE +LDEN-ESARDTIAEIGKLLHDY- +>[subseq from] Serine hydrolase n=1 Tax=Lactobacillus sp. FI11369 TaxID=2306423 RepID=A0A3R8KF67_9LACO +--AVQRDVDKALTGMGGTTSVAVLPVTGSGQV--VNNNQSQRAASLIKLFILVTVYQRAT +DQELSLDDSYSLQSSDKVGGTGTLQNLPNGSLTYREITKRMIDESDNTAANIMIAAVGGM +GNVNAEIKSLRLTDTKLERHLMDTA-ALKSGKDNYTSVKDVAKVLQRLYNHRLVSERADT +QMLSVLKNNAN-HAKLPKNLPSDAVVYNKTGEYNYGVQNDAAIIKNSRGA-FIAVVLSQD +GK--EASQVTAMNQLGAALYQ-- +>[subseq from] serine hydrolase n=1 Tax=Gaetbulibacter sp. S0825 TaxID=2720084 RepID=UPI00143092D5 +---LKTDIEQQIQTIEGDIAVGFLDLSNEENTiLINVDEKFHAASTMKVPVMIELYKQQN +QGLISLSDSIVLVNESIVDGSSYKYSKIGTKQTLYDLMVPMVTVSSNLATNVLIEIV-DA +KKTTQTMRDLGANKIEVLRGVEDIK-AYEQGLSNSTTARDLMVIMKAIANGTAGTKEDCE +VMLSILKDQQW-NDMIPKYLPDNVEVAHKTGSIT-GVHHDAAIVYPPNGKDYVLVLLSKN +LK-DFDEGTNKLAKISERIFS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=Q2FC76_STAEP +---HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANKKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTF--------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Alcaligenes aquatilis TaxID=323284 RepID=A0A3R9B7Z2_9BURK +-eRLQERLEPLLTQESARISMAVYATDGTSLF-DWHAQRVMPSASLIKTPMLLCLLEQVA +QGKLSLESVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM +DNINAWSAQAGLQHTDLQRHMMDMKAR-EVGKDNWTTAQDACLTLLYLLHSPALPENLRQ +QGLDMLADQRE-RGHFAAMLPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG +FT--------------------- +>[subseq from] serine hydrolase n=1 Tax=Nocardia sp. SYP-A9097 TaxID=2663237 RepID=UPI00129AD02D +----------------------------TAEV-TVDGHARVVTASVYKLPLFVAFCRSVD +AGRIDPTARLTVIPSDCTPPTGIAALHDPVTMSWRDLATSMMTVSDNAAADVLLGEI-GL +APVEDLLRDLGLTETRIVGGTADQHEAYDPTYASATTPEEMTRFLAALWTGTLISPAQTD +FVRAVMRNQVW-PHRIAAGFPRGVSVAGKTGTVGI-IRNEVAVVEFPGEYPVTVAVFTRA +ARADLPAVDAAIAEAARIAV--- +>[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A6B1FY08_9GAMM +--ELAARVTARLDGLPARTSLFARHLPSGREI-AIRADEPMNALSVIKIPVMVLAYRDAE +AGRLDLDERYRIRPEDLRRGSGLLQTFAPELPTWRDLITQMIITSDNTATDIMIARL-GQ +ERVNEMLSEFGYEQTRLRATTGELFRRFEGDSEEWITAREIAGLLEQIHNADVASRASSD +EMIRILERQFY-STRLPRYIRFRASVAHKTGDWPPYAGNDVGILYYEGG-PTVIAVFTNQ +NTGDFIELESTLGRIAEDIVNSw +>[subseq from] serine hydrolase n=1 Tax=Aliifodinibius saliphilus TaxID=1920650 RepID=UPI00110842C5 +--TLKSSIKKQLQEVKGDFAIAFKNLSDTTQVlYINEREKFHAASTMKTPVMIELFKQAE +IGRFSLGDSILVKNESIVDSSRYKYDLIGSKRTIRQLITDMITMSSNLATNILIEKV-GA +HNVTQTMRSYGADSIKVLRGVEDIK-AYERGLSNRTTAIDEAIIYEQLGRGKAVNKEASN +EMIEILKKQHF-NKMIPAQLPNEVEVAHKTGWIT-GVNHDVGLITLSNGEKYVLVLLSKN +AP-NREEVLTTFANISANIYE-- +>[subseq from] serine hydrolase n=1 Tax=Robertkochia solimangrovi TaxID=2213046 RepID=UPI00117C6649 +---LEATIQSQIDSIAGDIAVAFLNLSDPSDTlFIAADEKFHAASTMKVPVMIELFKQQE +AGTLNLNDSILLINESIVDGSPYSYDKINSRVALNDLMYSMITVSSNLATNVLIELV-DA +KNVTATMRDLGAQKIEVLRGVEDQK-AYDMGLSNSTTARDLQIIMESIASGKAGTKEDCD +SMIAILKDQQF-NEIIPKELPENVSVAHKTGSIT-GIHHDAGIIYLPDGGSYVLVLLSKN +LE-DFDKGTEQLAGISRSFYAH- +>[subseq from] serine hydrolase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013EF33DB +--EVTERIRAVFADAGCTGWLHARRCGSAAEI-SVGGRDRVVTASVYKLVLFVAFCRRVD +AGLIDPRAQLTVHPADCTPPTGIAALHDPVTMSRRDLATSMMTVSDNAAADVLLGEI-GL +GAVEDLLDELGLTETRIVGGTADVHRAYDPSYASATTPEEMTRFLHLVWAGGVLSPEQTG +FVRAVMRKQVW-PHRIAAAFPRGVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLAVVDAAIAEAARIAVT-- +>[subseq from] Uncharacterized protein n=1 Tax=Fictibacillus arsenicus TaxID=255247 RepID=A0A1B1Z532_9BACI +----ENDLLHLISSGKGVYGVSIYHFETEEEF-SHNQNEEFYAASIIKLPIMSAVFAQVA +EGKRSLSDKIQIRSEDIVSGDGILKNLSPGMWTIHDLVVLMIIESDNTATNLLIDLI-GV +ENIQLYMTIWGFKTTQFRHKLQ-IKPSRKHNESNLITAKEINNFLRNIAMGNIVSMSVCS +KMVDIMKQQKM-NGLLPSLLPENWEMAHKTGYVP-GVEHNAGLFYLPGQT-FAITALGKN +VP-NRDEPKRIMGELGLLLYE-- +>[subseq from] serine hydrolase n=1 Tax=Leptolyngbya sp. BC1307 TaxID=2029589 RepID=UPI000EFB487B +--ALKAQFEDLPNLYGLTAKLFYVDVDTGDYV-DLAGREAIAAASTIKLPILLAFFEEVD +AGRINPNQTMTIQPDQLADGSGEMQVAPGTQFTALEVATQMIVSSDNTATNMMIDLLGGS +AALNSKFAAYGLEKTRLNGPLPDLDGT------NTTSARDLAQTLLLVTQDETLTLRSRD +RVLNILQRTYN-KSLLAAGLEKEALTYNKTGDIAS-VLGDAALVDLSNGKRYIVAVLVER +PTND-GRAVELIRRISGRIYQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Prevotellaceae bacterium HUN156 TaxID=1520830 RepID=A0A1K1PA97_9BACT +------------------------KGGTER---RINATSRFPMYSVMKFPQALYVADFLT +RNDIDLNTEVLVRKEEMLQWSPMLSTFEDQRFTYSELLALSLQQSDNNACDILFERCGGP +RAVDKYLRDLGFKDIRIQKTEKQMHDTPALSEQNWCTPQSMVTLLEWFIAHHN-DNEPLR +YIWKLMAECQTGGDRLPAAVPNSAKVVHKTGTGYPSGICDVGIIILDNGQQLPIAIFIIN +PSSQ------------------- +>[subseq from] hypothetical protein n=2 Tax=Paenibacillus cellulositrophicus TaxID=562959 RepID=UPI0012673142 +-----------AEKDGIRMSVGIRDLSGHETL-LLGSHEPYMPASTIKLAVVSALMQQVD +RGELSLADQVRVTPEDVVGGSGSLQTSFPQNLTLERLARLMITQSDNTATNVLIDKV-GM +DRVQQLMDQLDLRTMHLGRKMFAAA--PSPAQDNYIDAADLTELLGQIYQGSFLSVSSRN +QIIAWMARQEV-STKFGAALP-DAPIAHKTGENAN-VTHDAGYFLVPGHE-LAVSVLLQV +TTEAQRIGNPIVQKAARAIYS-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535E3J0_9CHLR +-----------LDRARGVTGLVVREVGGATLF-SQRSDETFPAASVIKIPLVMALYADAA +EGRLSLDERMPVGA--IVGGTGILGDLRDVRVSLRDLAMLAIALSDNTATNRLIDRL-GV +ARIDARMAEWGCVRTKLARGMFDWDAQ-RRGLENVVTPSEMAGLLERLVCGELVDRATSD +AVIAVLERCQD-DAMLRRYLAKGARTANKTGTLE-ATRNDAAIVFGPTRT-IVVAAFMRE +VA--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium SW_4_67_19 TaxID=1919115 RepID=A0A2T2UEF9_9BACT +----------------ASVAVAVR--ARAPTF-DWHADRVFHAASTMKVAVLIETYRRVE +RGALALDDALAVENCFRSAGGGVFYDHLGGALPVRTLTERMVTRSSNLATNLLVERL-GA +DAVERTARRLGAGTMRIRRGVEDRA-AYRAGLSNTASARDLAALMNALMRGEAVSPQADR +AMIETLAGQRY-NSMIPAGLPSDTRVAHKTGWLD-ALHHDAAIVCPPGEVPYVLVVFTEG +IRAH-SRSARLGAEIARAAH--- +>[subseq from] serine hydrolase n=1 Tax=Aminipila butyrica TaxID=433296 RepID=UPI0013A77DBA +--MLKQYINERLSTLEGHAGVYYKNLKTGETV-LTEGQDQFLAASIIKIWIMAEAFRQME +EGTIKKDQKIILRDSDKVPNNKMPYLHAESEWTVEDLCRLMIIISDNTATNILIRLL-GM +TNINELIQSLNMSKTRLNRSLFDTSKK----IENTISLEETGLFLEKLYREELISSKASQ +EMSAILQNQQN-NSKIPFFLP-QIPIAHKTGEDN-GIANDVGIIYSD--IPFILCFAAND +SY--TPAANQACQDIAKAAYQY- +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A2S4ASY0_PSEST +--GLEQELRRIDDAAPGKLGVYIKHLGEDAEL-RYEAERFWYLGSAVKVPIAIAVLQGVD +DGDFRLDQQLSLEAEDKVDGSGLVWQDVGVDYAVRDLLNEMLIESDNTAANMLIRLV-GE +DDLNARTRKSMGSDFEAITTFTQV------------------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Lactobacillus kefiri TaxID=33962 RepID=A0A511DWN9_LACKE +--QIQHALQTCVNDASKKTSGYVKVIGDHQAI-HINGSRRQRSASDIKIFVMVEAFRQIK +AGTLHLNDMVSIPQDDKVGGTGQLANQDTNRLSCINLLNLMIKNSDNTATNVLIDKLGGL +APINKSIQELGCNNTRIQRKMLDYT-ALKAGRDNYTSADDVGKTLNAIYTGQLLGSNYDA +QMLQLLKGNAN-QSKIPALIRGSATIYNKTGEFDYGVQNDAAIIKHKNRA-FIAVVLSEN +GSQN------------------- +>[subseq from] VEB-1 n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A125S0H4_ACIBA +------------------------------------------------------------ +------------------TWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE +SKETSEINEKIISDIAKITWNYy +>[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium sp. ML3W TaxID=1538644 RepID=A0A088EVD0_9SPHI +-tKLDRKLRELTQNFAGDIGIYVKNLKTQEEV-LIQADTVFPTASIVKVPILVGIFNKIE +RGELNLDQKFIYRSSQQYGGSGVMQFFKDSTTDLATMVALMITYSDNVASIWNQQLAGGG +ITINLLMDQLGLPNTKVNSRTEGRNEIWEKYGWGQTTPKEMATLVELLYKGKVVSPKASE +NMYRHLGNIFY-NDRSLSQIPANIKTASKTGSVDE-ARGEVVLVNAPSGD-YVFCVLTNN +IKTKNNEAEDLTRKISHLLWNYf +>[subseq from] serine hydrolase n=1 Tax=Actinomadura hibisca TaxID=68565 RepID=UPI000836E841 +------HIERVFRDAGVTGHLYALDLDTGRDL-GVRGDDPVVLASVFKVPLLVAFHRRAA +AGLLDPTERVTLSPEERAPPTGIATMLDTVTLSLRDLTNLMITVSDNTAADAVFARV-GL +DAVNTAMADLGLSHTHLTGNGGELHDALDPSRTTRSTPREMARLLAMIWRDEAAPPEACA +EMRRLMGLQVW-PHRLSSGFPDDVRVSGKTGTLPT-LRNEIGVVEYPDGGRYAVAVFTRS +FQAVLPEADAAIGTTARLAIE-- +>[subseq from] Beta-lactamase n=1 Tax=Prevotella disiens FB035-09AN TaxID=866771 RepID=E1KQY7_9BACT +------------------------IVNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD +FKGNESQASQYVAHISAVVYS-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2W1ATI9_9CHLR +-------------GFAGVAGASVKDLSSGDGV-SVRGDEQFPTASTIKIHVLTQLFSRAE +RGELDLSKRIRLTSEMFGAGSGVIHYMENELLSLLDIATLMIIVSDNTATNMCIDLA-GI +EGTNELLDTMGLKSTKLRRKMMDSD-AIRRGDENVSTPNDLVAMLTLLYSGNP-SKKVAE +QVLHIIGKPKS--ATINRGVPSGLVVANKPGGMER-VRCDAGIVFLEKN-PYALSVMTNF +GLEDGVKQEGFIVEVVKEI---- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium QH_2_67_10 TaxID=1919095 RepID=A0A2T2SGG3_9BACT +----------------ASVAVAVR--GRAPTF-DWHADRVFHAASTMKVAVLIETYRRVE +RGALALDDALAVENCFRSAGGGVFYDHLGGALPVRTLTERMVTRSSNLATNLLVERL-GA +DAVERTARRLGAGTMRIRRGVEDRA-AYRAGLSNTASARDLAALMNALMRGEAVSPQADR +AMIETLAGQRY-NSMIPAGLPSDTRVAHKTGWLD-ALHHDAAIVCPPGEVPYVLVVFTEG +IRAH-SRSARLGAEIARAAH--- +>[subseq from] Class A beta-lactamase n=1 Tax=Bacillus sp. AFS015802 TaxID=2033486 RepID=A0A2A8V9X7_9BACI +--MLEHSIQEIAERCDGMVSVAV-DLPSQ-AI-HINGDRPCSAASLIKIPILLEGFRQSE +KGMISLSEKVYVPKDERVGGAGVLTSLSENVLTIEDLLTLMIIVSDNTASNLLIDRL-GS +KPIQDLCHSLNLKQTKLMRKLMDFKA-MEQGLNNFTSAHDIITCLKVMDNGEQFSQTSRE +KMLNILQQQQF-DNKLPSRMDEKVFVANKTGELP-GVEHDCAILKFKNKT-AYIAVLIDE +LDE-NEYGKDTIARIGKLIFN-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. VT-16-64 TaxID=1917019 RepID=A0A1V2SFW7_9BACI +--TVEIRVKKLMEQAGGDWGIMIEDIQNDISW-GYEAHTPFPAESIIKIPIMAAVFSAAE +NRQLRLSDCVSMNQGDQVGGAGALQYVTPGILSIYDLLVLMIVQSDNTATNMLIDLV-GM +EAIQQTLLEAGMKNSHFQRKLMVYPAR--EHLQNIVTAADVSFMLRKMAAGQLVSRHACE +QMIQIMKWQQY-RNGLPSQLPPKWELAHKTGWDLN-RQHDAGILYTGQR-TMIISVLSEN +VS--SKTALDVLGEIGKAVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Muribaculaceae bacterium Isolate-104 (HZI) TaxID=2486471 RepID=A0A3N2MHN2_9BACT +--SLQSELENYISEKNCRIGVAVIC--GDDTV-AVNGDEYFPMQSVFKFPQAVAVAAFCD +KNGIVPEDSVSIDSSMILRYSPLREHYGVVSIPIGELLEYSLVQSDNNACDILFDIIGST +AVADSVIKSMGFSDIDILHTEADMHLDTALCHKNRTTPVEMARFTEYFRNNLADSTPFMR +AVRQNLELCATGMSRIPADFEDGTLIAHKTGTGDISAVNDAGYIELPEGKSYSIAVFVAD +SPAGMEATEAIIGDISEIVR--- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=A0A4U8VUJ7_9NOCA +--EVTERIRAVFADAGCTGWLHARRCGSAAEI-SVGGRDRVVTASVYKLVLFVAFCRRVD +AGLIDPRAQLTVHPADCTPPTGIAALHDPVTMSRRDLATSMMTVSDNAAADVLLGEI-GL +GAVEDLLDELGLTETRIVGGTADVHRAYDPSYASATTPEEMTRFLHLVWAGGVLSPEQTG +FVRAVMRKQVW-PHRIAAAFPRGVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLAVVDAAIAEAARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Anaerolineae bacterium TaxID=2052143 RepID=A0A3D4JGT2_9CHLR +-----------ISQFNKTISVSVYDLETNQEI-NIHADVMMHPASTMKVPVMMEIFRQSH +AGIFSLDDKIEIYNSSIVDGNDFDYARIGEKETIRELNRLMIVWSSNLATNILMDKV-GT +KPIDNFIKTLGIKDVNIMRLIED-NKAYRLGMNNTFSARGTTHMMRLIAEGKVISQEVCD +EMIQVMLGQEF-NESIPALLPKDVKVAHKTGWTGE-FFHDTGIVFPSIRKPYAITLFTNG +FPNDEFQAHNCMAEISKLIYE-- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. K20C18050901 TaxID=2291814 RepID=A0A3E1NYM9_9BACT +-qQLEKGLRNVISGFRGDVGIYVRNLKTGHYA-EINADSVFPTASIVKIPILIGVFDKIE +KGELQYHQPLVYRDSAKYGGSGIMQYFKDSSTELSVLLALMMSYSDNTASLWNQALAGGG +ERINQLMEQYGMQVTRVNSRTAGRQEIWKIYGWGMTTPREMATLMLKIRNGEIISKSASE +RMYRLMTHPYY-DEGAISAIPPYVQAAHKSGAVDE-SRSEVVYVNAPHGE-YVFYIGTKN +IATDDNEASALIRKVSKYLWEYf +>[subseq from] Uncharacterized protein n=1 Tax=Armatimonadetes bacterium RBG_16_67_12 TaxID=1797288 RepID=A0A1F3CC62_9BACT +-----EEIQALADCFSGTLGVWASLLDSGETL-EWNATDDFPAASTIKLPILYEVFRQAG +ECRFTLTDPMTLRAEDIVPGSGILKDLTPGLLPIRDLATLMIVISDNTATNMLIDLV-GL +DAVNGSCEALGLTGTVLAFKL---FRGPDGAPRNRSTPVDLGRLMTGVAGHAVLTPPACD +EVLAILGRQHF-TDLITRRLTPRVAVASKSGSIR-GTRNDVGLVSARGQ-RYVVAMMSKG +CADEDNEAAVLLPRVSAAIYRHf +>[subseq from] hypothetical protein n=1 Tax=Lactobacillus murinus TaxID=1622 RepID=UPI00096C57DC +------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK +IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYHELLAYMIDESDNTAANIMIDALGGI +DKVNTQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA +EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENEKGA-FVVVVLTQN +GDNNEEQ--AA------------ +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5TE53_9BACT +---LNEELETLSSESKARIAVALHDLESGLRF-SLHGDRWFHAASTIKVAVLLAIFRAAD +EGRLRLDDSLHVRNRFISAGSSFHYQAIGRTAKISALAEGMIASSSNLATNLLLDFV-GV +EYARNVLRDAHVEGVELRRGVEDH-AAHERGINNEATANGLLTLLSA-VRGNFLSSDSKE +QAIRILLQQRF-RSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EHDGRRETVAAISEAIFR-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia fusca TaxID=941183 RepID=UPI0007A7466A +----AERIRAVFADAGCTGRLHARRCDSDAEV-SIGGTERVVTASVYKLPLLLAYCRAVD +AGRLDPLARLTLIPSECTPPTGISALHDPVTMSRRDLATSMMTVSDNAAADLLLGEI-GL +AAIHELLESLGLELTRLVGGTADIQRAYDPAYTSATTPEEMTRLLGALWRGEVLSGEQTD +FARAVMRRQVW-PHRIAAGFPRGVAVAGKTGTIGI-IRNEVAVVEFPGEHPVAVAVFTRA +ARADLPAVDAAIAEAARIAVT-- +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Sulfopaludibacter sp. SbA6 TaxID=2043166 RepID=A0A2N9MQ10_9BACT +--PLQQAVKARIGDFQGTVSLYAKNLDTGAAL-GIRESEPVRTASTIKVPIMLAAFDAVS +RGQAKWGEPLTVAAAQMVSGSGILGSEMSDGLPLRDVVHLMIVLSDNTAANMVLERF-TA +DAVNAYLDMLGIRTTRALRKIRGDGGENEKYGIGVSTPRDMVTILEKLERGEIVSKDASR +EMMAILKRCQD-GSGIRRRMG-GLMVANKTGALD-ALRSDVGIVYSKNGR-IAMAITVDG +MPTPDNAGSLLIADLAKILVD-- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5MA19_9BACT +---LNEELETLSSESKARIAVALHDLESGLRF-SLHGDRWFHAASTIKVAVLLAIFRAAD +EGRLRLDDSLHVRNRFISAGSSFHYQAIGRTAKISALAEGMIASSSNLATNLLLDFV-GV +EYARNVLRDAHVEGVELRRGVED-HAAHERRINNEATANGLLTLLSA-VRGNFLSSDSKE +QAIRILLQQRF-RSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EHDGRRETVAAISEAIFR-- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A524HAL1_9BACT +---LRSNLEAGVPPTGTEVGLALIDLGTGDSL-WINAQWRVHAASTMKVPVLIELAQRVD +VGQYGWEWPVLVKNESIVDSSSFQTLFAREGVTARELARLMITWSSNFATNLLVDQL-GA +SRIQATAWRLGADSIVVLRGVEDQK-AYDRGLSNTTTARDLAVLLAAIVEGRAASDSSTA +IMIDILTHQRF-RQGIPAGVPPGTRVASKTGGIT-GINHDAAVIYPTSRPPYVLVILTRG +FARP-TDAEAYMASISAEVW--- +>[subseq from] serine hydrolase n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=UPI00130DABCF +------ETIEKLKKLPGKISFYYRSLDSEDTA-EYQADQPLMAASVIKLFVMTEAFARIE +AGKLNPDAMITVKRADCVPSCGALNYHDNVQVTVMDLITLMIILSDNTATNVMIDLL-GI +DAINAQIRSLGFEKTVLKRKMFDSEKA-AQGLENYISAKEAGLLLEKMYRGTLISEKASA +KMIEILKNQRL-NHKIPFYIKGGPAIAHKTGEDS-GITHDCGIVFAEH--PFVVCFCGNE +T--DVTAYERTMAEIALEIYK-- +>[subseq from] Uncharacterized protein n=1 Tax=Oscillibacter sp. KLE 1745 TaxID=1226323 RepID=U2QQI6_9FIRM +-------VKRQLSSVPGHIGFYYKNLVTGETD-GSRQTELFQAASVIKLPILAAILLEER +EHPGVLQERLLVRDGDKVPGCGALQHISGTQYDIESLCKLMITISDNTATNVLIRRF-GI +EFLNERFRALGLQETKIFRFLFDTEAA-RQGKENLCQPKEIGSLLEEIYHGRCVSANASE +RMRAMLSQQQI-NHKIPSLLPPTVRVEHKTGEDE-GITNDVGILY--GREPCVLVFVSNE +TD--VPAFEQVIRTVS------- +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6AWT9_9BACT +--TLAKELDRLAAERKATIAVAVHDLETDFRF-SLRGDRWFHAASTIKVAVLLAVFRAAD +GGRLRLNDSLHVRNRFFSAAGGTVYQSIGRTAKISVLAHAMISGSSNLATNLLLDFL-GV +ECARTALRDARVEGVELRRGVEDH-AAHEQGINNQATADGLLSLLSAI-RSDFLSNESKQ +QVIRILLEQRF-NSMIPAGLPSHAMVAHKTGEIST-VSHDIGIVYLPEREPYITAILTEF +DP-DQEGRREAVAAISKAIYR-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia transvalensis TaxID=37333 RepID=UPI0012F67855 +--------------------------GSDAEI-SVGGGERVVVASVYKLPLLLAFCRQVD +AGRIDPTARLTVHPADCTPPTGLAVMRDPVTLSLRDLATSMMTVSDNAAADVLLGET-GL +GAVEELLDDLGLTRTRVIGGTADLHRAYDPSYTSATTPEEMTRLLRALWTGEVLSGEQTE +FVRSVMRHQVW-PHRIAAAFPRSVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLPVVDAAIAETARIAV--- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus animalis KCTC 3501 = DSM 20602 TaxID=930942 RepID=A0A0R1ZX38_9LACO +--------------------VYVAPMNEDVSY--LLNNQTQSAASVIKLFILAAAYAQQK +IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLTYMIDESDNTAANIMIDALGGI +DKVNAQIEKMGAYDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA +EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENEKGA-FVVVVLTQN +GDNN-EERS-------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus antarcticus TaxID=238540 RepID=A0A3E0DUC5_9BACT +--DLQTTVQSQMDSIQGDVAVAFYNLSENDSL-LIKAGEELHAASTMKVPVMIELFKQAK +EGKINLDDSILLKNESIVDSSLYSYSKIGTTVALRDLMYSMITVSSNLVTNVLIELV-GA +KNVTATMRELGADKIEVLRGVEDTK-AYELGLSNSTTAKDLMIIMKAIADKTAGTETDCE +QMIAIMKDQQF-NTIIPFYLPENVKVAHKTGAIT-ALHHDAGIVYLPDGRSYVLVLLSKN +LK-DYDTGTEQLAGISKTVYEY- +>[subseq from] Serine hydrolase n=1 Tax=Lactobacillus brevis TaxID=1580 RepID=A0A3B8EAA5_LACBR +---------QTMGQLAGQNAVYIQ-TTGGQTL-SWRNRS-QKAASDIKLFILATVYRQVT +AGTFNLSAPYTLRAADKVGGTGNLQAQPDGTVTNRDLLRAMMTVSDNTATNIVIRRVGGL +SAVNQEIKRLGATQTVLRRKMMDQQ-ALAAGRDNVTSARDLGQLLMKLWQHRLISPTADA +AMLKLLAANTN-HTKLPRHVPAGRQVYNKTGEFDYGVENDAAIFAQGKRA-VVVVALSQH +GRLD------------------- +>[subseq from] serine hydrolase n=1 Tax=Echinicola rosea TaxID=1807691 RepID=UPI0010CA83F1 +--ELRETINTRLNKVEGDFAVAFRVMGEDPLTlLINEKETFHAASTMKTPVMIALYNQVA +MGNVSLDDSVKIVNESIVDGSPYRYSRIGQYSTYRELNYEMITMSSNLATNILIDKL-DA +KKITETMRSLGAMDIEVLRGVEDLK-AYERGLSNTTTAYDLMLIMEAIAARNAVSEEASL +AMFEVLKAQHF-NEIIPGQLPEEVVVAHKTGSIT-GVRHDSGIVQLPSGEKYVLILLSKN +LN-DPEEGIRAMSDVSKILYD-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia rhamnosiphila TaxID=426716 RepID=UPI0004C3A324 +----AERIRAVFADAGCTGRLHARRCDSAAEI-SIGGTDRVVTASVYKLPLLLAYCRAVD +AGRLDPLARLTLTPSECTPPTGISALHDPVTMSRRDLATSMMTVSDNAAADLLLGEI-GL +AAIHELLESLGLALTRLVGGTADIQRAYDPAYTSATTPEEMTRLLTALWRGEVLSGEQTD +FARAVMRRQVW-PHRIAAGFPRGVAVAGKTGTIGI-IRNEVAVVEFPGEHPVAVAVFTRA +ARADLPAVDAAIAEAARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3D0QHP2_9BACT +--VLQQNLETLVKGFKGDVGLYVRHLGTGQTA-AIQADTLFPTASMVKVPILCAVFDKIE +KGELKYNQQLLYRDS-LKYDDGITGSFRDSTIQLSEIVMLMITLSDNTAALWLQHLAGTG +TTINEWLENYGFHQTRVNSRTPGREAQRRVYQWAQTTPREMATLLTTIFQGRAVSPAASE +QMFRVLSKQYW-DAEGLSQIPPTVHAATKNGAVN-ASKSEVVLVNAPSGD-YVYCVITKN +QQEDDNEGNVMLRRVARMLWKYf +>[subseq from] serine hydrolase n=1 Tax=Halomonas sp. QHL1 TaxID=1123773 RepID=UPI0009F822D9 +------------------------------------------------------------ +------------------------------------------------------------ +---QALARALGVSTQSFTQDYDHAFDAYEATGENVGTLSAFGDLLASLHPMDDLGDEQRQ +TLLALMQRTSSGKRRLKAGLGDSVSFAHKTGTQQR-RSCDAGIAERTAEGPWVIVTCTRG +PEA-VSAHERALARVGEAL---- +>[subseq from] serine hydrolase n=1 Tax=Candidatus Kryptonium thompsoni TaxID=1633631 RepID=UPI000707450A +--EIVSKINQIGKKYGGRLGVSAKNFVTGETI-QINADSLFPTASVIKVPILVELFYKFE +EGKLKKDTLISFDDSLKYGGSGVLQYFYDGALKLIDVAVLMIILSDNTATNLVLDCFADL +EAVNNRVKDLGLNNTKILNKLMSFKTKTPEATRGYTTPNDMVKLLELLANGKVINPEISA +EIINIMKNNQD-YEMMKRYLPENVTVANKSGSIDR-MKADIGIVYAKCV-TYAVAIFCDE +LSAVDNKGHLAVAEISKLIFDYf +>[subseq from] Beta-lactamase n=1 Tax=Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) TaxID=479432 RepID=D2BES4_STRRD +-----------FRAAGVTGFLHAVDVDTGAEV-AHGADEPVVMASVFKLALLVEFFRQAD +AGRLDVTERVTVMADRHTPPTGVSAMADDVTMSLRDLAYLMIAVSDNTAADALIGRV-GL +SAVNTMLAAEGLDGTWVEHDCRSLFAALDPARTSRSTPRDMTRLLGMVWRDEAASAASCA +SMRRLLGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +TAQNQPRADAVIGTAARAAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium sp. CAG:226 TaxID=1262781 RepID=R5B6B2_9CLOT +-----------LKAVPGNVGFYYKDLTSGETL-GYNENEQFEAASVIKLPVYMVIMKLAH +EGKLSLSEKLTCHHADKMPPCGALYFFTDEPVDIETLCGLMITISDNTATNMLISRL-GI +DFLNEEFKKIGLEKTHIERLLFDSEAS-AQGKCNYIVPAEMGMLLEQVYRRTFVSKEVSE +AIEKLLLEQQI-NHKIPGYLRDEVAVAHKTGEDDN-LTNDVGIVYAE--KPFVVSFASYN +TD--VPTAEIAIREISR------ +>[subseq from] serine hydrolase n=1 Tax=Streptosporangium roseum TaxID=2001 RepID=UPI0005BD889C +-----------FRAAGVTGFLHAVDVDTGAEV-AHGADEPVVMASVFKLALLVEFFRQAD +AGRLDVTERVTVMADRHTPPTGVSAMADDVTMSLRDLAYLMIAVSDNTAADALIGRV-GL +SAVNTMLAAEGLDGTWVEHDCRSLFAALDPARTSRSTPRDMTRLLGMVWRDEAASAASCA +SMRRLLGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +TAQNQPRADAVIGTAARAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Runella zeae TaxID=94255 RepID=UPI00055D9803 +--------------SKMRINIQVESLDGHVYF-SQQSQETVPSASVIKIPILVELMEQVK +AGRFQLEDKYLLADSDKVGGSGVLSKRMAGEMNIDELARLMMIASDNTATNVIIRKV-GR +ENINHRSKSLGLEGLQLNRVMMDTVA-VARGIDNYVTCRDINTLLRLIYHQKVATPMLCE +RMMGFLYENQD-TLTLPRLIPKHVKIAHKTGGLAY-VRGDAGIVFG--EVPFVISVFIRD +TK--VEEAEKMLGEIGEICF--- +>[subseq from] Beta-lactamase class A n=2 Tax=Nocardia ignorata TaxID=145285 RepID=A0A4R6PTZ2_9NOCA +------RIRAVFADAGCSGWLHARRCDSAAEI-SVGGRDRVVMASVYKLLLCVAFYREVD +HGRIDPAGRLTIDPADCTPPTGIAALHDPITLSRRDLVTSMMTVSDNAAADVLLGEL-GL +AAVTDMAAELGLTETRVVGGTADQHRAYDPAYASATTPEEMTRLLWRLWSGDVLSTESTE +FVRAVMRNQIW-PHRVAAGFPRGVVVAGKTGTVGI-IRNEVAVVEFPGEIPVAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Halomonas sp. QHL1 TaxID=1123773 RepID=A0A1J8Q8E2_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +---QALARALGVSTQSFTQDYDHAFDAYEATGENVGTLSAFGDLLASLHPMDDLGDEQRQ +TLLALMQRTSSGKRRLKAGLGDSVSFAHKTGTQQR-RSCDAGIAERTAEGPWVIVTCTRG +PEA-VSAHERALARVGEAL---- +>[subseq from] Serine hydrolase n=1 Tax=Rickettsiales endosymbiont of Stachyamoeba lipophora TaxID=2486578 RepID=A0A3Q8T5A0_9RICK +--DLTHLIHSLEKQYNAKIGVSITNVNHNVSY-HHRENEHFKMASTVKLPLAVYWLYLLE +HNKVNFDELVEIKPNDLVPGSGKLGYHPGFQISYRNIFEPMLTISDNTATDMIFKKVGGA +NNLRKFLINQGFNQIWVNRSIMGLFFQFHTDVRDTATPLQMNQLLINIANYKVINKQSFD +YLFDVMSRCSTSENRVKKWLPKGV-VIHKTGTWDYQYLGDVGYIQTRKG-MVAYSIYVET +KLQGNLVSEDIFAQLGKVIYENy +>[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. Bc-iso-3 TaxID=1848158 RepID=A0A1E3BVP8_9CLOT +-aALESKLKKYISKYNCQFGIYFVDLESGSEF-GINAEEEYFAASTFKIPLNLYVYDRIR +EGIIDADTTLEYTEEDYEGGAGIIWSRESYGYTVRELLRLSIVYSDNVAVNMLLRYV-GK +ENVKNYMREMGGIVV--------------DDKKNLSCPRDMALYLKKVYELSENGDPLGK +ELVRNMVNTKF-YDRLPVLLPKNVKIAHKTGNLI-GVVHDVGIVYAK--RPYIIVVMTKN +VK-NERSANKAIANISKITYDY- +>[subseq from] Serine hydrolase n=1 Tax=Hungateiclostridium mesophilum TaxID=2487273 RepID=A0A4Q0IA86_9FIRM +-aALESKLKKYISKYNCQFGIYFVDLESGSEF-GINAEEEYFAASTFKIPLNLYVYDRIR +EGIIDADTTLEYTEEDYEGGAGIIWSRESYGYTVRELLRLSIVYSDNVAVNMLLRYV-GK +ENVKNYMREMGGIVV--------------DDKKNLSCPRDMALYLKKVYELSENGDPLGK +ELVRNMVNTKF-YDRLPVLLPKNVKIAHKTGNLI-GVVHDVGIVYAK--RPYIIVVMTKN +VK-NERSANKAIANISKITYDY- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0013F641C9 +------------------------------------------------------------ +------------------------------------LIEASMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] VWA domain-containing protein n=1 Tax=Clostridium sp. CL-6 TaxID=1499683 RepID=UPI00069464A2 +--KILEMVKNYTSNAEGRYSIYYGNVDMGFPM--IVNDASIRSASVIKIFIMIEALAQID +--KKLLDGNKLVTMNSCVGGTGVIQEHIGSQFTVYELLEYMMIDSDNTAANMLIDEVGGV +AVVNAKIKELGCVNSQMNRKLLDME-ALRNGQDNYVTVYDMGNILTKIYNKQCISEEADS +YMLQLMHRNKN-QNKIPYDLPENVNVFNKTGEFDYGVQNDVAIVETEKGA-YVLCVLTEG +GN--SQEEIGIIRRLSKDIYNEf +>[subseq from] Beta-lactamase class A n=1 Tax=Deinococcus yavapaiensis KR-236 TaxID=694435 RepID=A0A318S7N1_9DEIO +--------ESLLARHPGAVSIIVRDAETGDLLfERSPDRPFHAASTIKVPLLVRALQRVD +EESLSLDERREMRSKDQVGGAGVLHELGPGLLTLRDLLTLMIIVSDNTATNIVIDLL-GI +DDVNAFLRAQGFTVTDLVGKLERHNERQRRGERNRANARELCELLYRLTRGTLLSPASTA +LALDILRRQQL-KDIIGRRAPRDFEIASKSGELR-GVHHDVGVVRTK--RPLVIAVLSDG +GEREHPENRELLAEVVSVLME-- +>[subseq from] Beta-lactamase n=2 Tax=Thermomicrobium roseum TaxID=500 RepID=B9L2F1_THERP +----QRTIEQLIGQVPARVMLLFRDLDEDLEI-AYDADRPVVAASTIKLLVLARLYRAFA +REQLDPRARVRIASDQVVPGSGVLRWLAEPPMTLRDLAVLMTIVSDNVAANALIDVL-GF +AAMEELVVELGLTGTALRRPFWGR-AAYPGEPENLVTARDLATLLAALELGHIVPEGHWD +DLRMLLRAQQF-RDIIPARLPEAVIVGNKTGTLL-GSVHDAALLWAPFGR-AVLVLLTSG +V-TDFEATRRALADLAKEVVDHw +>[subseq from] Uncharacterized protein n=1 Tax=bacterium SCN 62-11 TaxID=1660156 RepID=A0A1E4FNB1_9BACT +-dKLKKTVQSLIARSGASTAVSIVDLQSNERV-DVQADEAYPLASVFKVPVMIELARQIQ +QSPLQLTTQLAMKASDRCIGSGSFQHRPVGTASLQQLVEWMETKSDNTATDMIFRRI-GL +TSVDTYLAGLGCTSSQI------------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=bacterium SCN 62-11 TaxID=1660156 RepID=A0A1E4FNB1_9BACT +------------------------------------------------------------ +------------------------------------------------------------ +-------QALEDRSARVQTSEENTLVA--TAVDNKLSSRDLALVLEKLYRGQLLDKKWTG +YCLGVLGRQTF-NTRLPRSLPREVKVYHKTGTIS-GVVNDVGVLELEPGRGLVVVVLVQQ +VQGDEGAADRLIGDIASVAYKAy +>[subseq from] Uncharacterized protein n=1 Tax=Klebsormidium nitens TaxID=105231 RepID=A0A1Y1HU06_KLENI +-eELQRLVARQERKKKMHVGVVVEHLPSGERV-SINGREPFPLASVAKVPIIIAAAQQLQ +EAEVRLTTRLRVTEDVKCIGSGELHERPSGEATLGECMELACVVSDNTAADLVLQQA-TL +GRVRALLREQGLHHTDL------------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] hypothetical protein n=1 Tax=Oceanobacillus manasiensis TaxID=586413 RepID=UPI000A568C87 +---LKASIQREIHE--AQAQYSILLTSRGESL-AINGDKIRPAASLAKIPILIEVCRQID +SGKLHPEKLVYIEEEQVVGGSGIISYLSNSNYSYLNLIELMIIVSDNTAANILLDSV-GI +DTVNHTVEKLGAKDTVIQRKFMDTEAQ-GLGQENYTTAKDMITLLKAITEGHYISSKSRE +FMKNILAKQQL-TNKLAKYIQPSVSIFHKTGELC-GVEHDVALLESNKE-KVYIAVLSDQ +LP-SNAEGQRTIAQIGKHVIDY- +>[subseq from] Serine hydrolase n=1 Tax=Pseudorhodoferax sp. Leaf274 TaxID=1736318 RepID=A0A0S9NIF0_9BURK +------------------------------------------------------------ +-----------------------------------------------------------P +QRAEAVRRALDLPAGALRADIDTAYAGYYADGHNSATLVGYGAMLERLVRGELLSPASTE +RLFEAMKYGKRGDYRLEAGLPAQRRLIHKTGTQFE-RACHMGVVEPQDKHAVVLAVCAAG +L-DEQRAAGRLFEQVGAAI---- +>[subseq from] Serine hydrolase n=1 Tax=Clostridia bacterium TaxID=2044939 RepID=A0A2V2E8W6_9FIRM +-----------LKAVPGNVGFYYKDLTSGETL-GYNENEQFEAASVIKLPVYMVIMKLAH +EGKLSLSEKLTCHHADKMPPCGALYFFTDEPVDIETLCGLMITISDNTATNMLISRL-GI +DFLNEEFKNIGLEKTHIERLLFDSEAS-AQGKCNYIVPAEMGMLLEQVYRRTFVSKEVSE +AIEKLLLEQQI-NHKIPGYLRDEVAVAHKTGEDDN-LTNDVGIVYAE--KPFVVSFASYN +TD--VPTAEIAIREISR------ +>[subseq from] Serine hydrolase n=1 Tax=Microbispora sp. Gxj-6 TaxID=2614688 RepID=A0A5J5KDW5_9ACTN +--------ERVFRGAGVTGWLHAVDVDGGREV-GLRAGESVVLASVFKLPLLLELYRQAE +RGLLDLAGLVRVPAEGRTRGTGLAAMLDDATLSLRDLAYLMMTVSDNAAADALLARV-GR +EAVNALLDRLGLTETRVVHDCRDMLTALDPARSNRSTPREMTRLLAMIWRDEAAGAASCA +AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +LSQNQPRADAAIGAAARVAIDQ- +>[subseq from] Serine hydrolase n=1 Tax=Caulobacter sp. B11 TaxID=2048899 RepID=A0A2G4JRD0_9CAUL +---------------------------------------------------AAAALAQIE +SGRLSAEEIIEIRDIDLSPRSAIAEAWPKRAYTLGELIERAVVDSDNTAADAVMKRIGGP +GVVTSWLEGKKVKGVSVDRYERQLQPAYLADRRDTATPIGAVRFLEALAQNELLSPAYSR +RLNALMTRSSTGLARLAAATPPGGTLAHKAGTGRTAATNDIGLYTLKDGRRIAVTVFLTG +STQDAAAREAVIAEVGGIVMA-- +>[subseq from] Serine hydrolase n=1 Tax=Bdellovibrionales bacterium TaxID=2053517 RepID=A0A3D3GBS9_9PROT +------------------------------------------------------------ +------------------------------------------------------------ +ARLNTFLRKLRITREELQSTIEDAFERYYRKNTNSGTLEAFGKLLENLFTGRLLNKVHTG +MLLEHLNRIETGEKRIKAGLHADTPFAQKTGTQIN-RICNVGIVHPKESEGWVVAACLEN +FQN-QSQAEKALTNLGQA----- +>[subseq from] Uncharacterized protein n=1 Tax=Halotalea alkalilenta TaxID=376489 RepID=A0A172YJ17_9GAMM +---LAPLVAQIDEEFPGELGFYLRDLDSGEYF-SLRAQEQWYLASMVKLPVALALLDMVD +RGEASLDERMTLNASDYVDGAGETNWHGPGTLRLGWLLEQMIIRSDNTATDMLIRRI-GI +ERVNARRAELVAHGFGEITTLADVRRAYYATGANSGRLDAHALLLERLQRLEALSTPSTV +HLLGVMSRVVTGEHRLKAGWPDSVGFAHKTGTQR-GRFCDGGIASRTVGTRRLVVVACTR +GSLSLADAERAMRELGAAAWR-- +>[subseq from] hypothetical protein n=1 Tax=Dechloromonas sp. Dech2017 TaxID=2570192 RepID=UPI0012928061 +---------------------------NGDLYcGHQEDSAFAMHSVMKFPQALYVADYLH +KKGLTLSDSVLVHKDSLDAWSPMLSIFEGMRFTFAELIEWSLKQSDNNACDLLFASCGQP +DAVEKYIHTLGFKDIHVQLTEKEMKKNPHRAIENSATPKEMARLLEWFYLHRN-DNKNLS +FIWDTMADCNTGQQRIAAVLPKDGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFLQK +SKEEKEVAEVAEQ---------- +>[subseq from] Serine hydrolase n=1 Tax=Halomicronema excentricum str. Lakshadweep TaxID=2294035 RepID=A0A4Q7EAH1_9CYAN +----ETDLVALETMTGLTQSVFFYDLDSGNYI-ELNGTEPIAAASTIKVPILVAFLQAVD +AGTVRLDEAVILREDLMAGGSGFQTQEIGSQFTALEAATAMIVNSDNTATNMVIELLGGL +QVLNQQFANWGLSSTSLRNPLPDLDGT------NTTSAADLVRIMALVEQGDLLSRRSRD +RLLGIMQRTYN-RDLIPDGLGDSALTFNKTGDIGT-LLGDVALVDTVNGNRYLLSVLVDR +PFND-GRASELVRRVAG------ +>[subseq from] Beta-lactamase class A n=1 Tax=Psychrobacillus psychrodurans TaxID=126157 RepID=A0A1I4U0Q3_9BACI +-eKLVSRIEKLIVPSKGTWGIVLEDLNSGEKW-EHNEQELFYAASVIKLPIMASVYSAVE +RGDLALTDLIILDEQDYVGGSGVIQHFTPGSLPLKDIIMLMIIQSDNTATNLLIDLV-GV +ESIQNTMKEVGMVYSTFLNKLMLSKPNPK--GANCIAAVDISVLLHEMAIGGLVSNKASD +QMVDVMKKQQV-RDCLPEKLPAPWELANKTGWIP-GTRHDVGIFYVGDRE-FIATVLSKD +ED--DLISKRILSQIGEEIYNY- +>[subseq from] serine hydrolase n=1 Tax=Caulobacter sp. 602-2 TaxID=2710887 RepID=UPI0013ED349A +heAMSHKLAAIAERAPGDLGVAVQDLTTAQRA-AVAGEQLFPLAGIWTAPLGAAVLAEVE +AKALSLRETITVEDVDLSPPSGVADAWPGRRWTVEELLKQAVAAGDNTAADVLMRRIGGP +GAVTAWLDLKKVENLRVDRYARQLLPDYLADTRDQTTPLAAVRFLEALNQGELTSQEDRR +RLLRMMEAAA--GDRLRPALPAGARLAAVTSATPAAADNTLAMVRLKDGRRFALAIFLKA +SPLEEADRDDLVLEVMRLVLQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Mediterranea sp. An20 TaxID=1965586 RepID=A0A1Y4HT44_9BACT +---LRQKIISYVAEKPAQIGVALV-VDSRDTI-CVNDACRYPLMSVFKLHQAMAVTRWLR +AHGTSLDFPVSLTPADLKPYSPLRDCYPQAGLPVGRLLTYTLQWSDNNACDILFDRTYSV +EQTDSCLHSWGLDHFSLSVNEDEMHDCPERCYDNWSTPLSVACLLEMLFTHPAFAGAEEA +FVRRQLQECATGRDRLAAPLETKALIAHKTGTSDRNGINDAAFVSLPDGRHYTLVVLVKD +SAASMEETCRYLADISAMVFA-- +>[subseq from] Uncharacterized protein n=1 Tax=Euryarchaeota archaeon RBG_19FT_COMBO_56_21 TaxID=1797983 RepID=A0A1F9ZZ06_9EURY +--KLRSEINKIARDVKGQFGLYLKHVESGKEV-AIDADKIFPLGSVFKIPVMMEVYRQAS +EGIVSLDEKLRLEPRYYCIGSGILQYLTPGLLTVRDLITLMIIATDNTASEMLWKRV-GI +QRVNMLMRELGLHKTSI------------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Kryptobacter tengchongensis TaxID=1643429 RepID=A0A656DCA2_9BACT +--TIVSKINQIGRKYGGRLGVSAKNFVTGETI-QINADSLFPTASVIKVPILVELFYKFE +EGKLKKDTLVSLEDSLKYGGSGVLQYFYDGAIKLIDAAVLMIILSDNTATNLVLDCFANL +DAVNNRMKELGLDNTKILNKLMSFKTKTPKAIRGYTTPNDMVKLLELLANGKIINPDVSA +EIINIMKNNQD-YEMMKRYLPENIVVANKSGSIDR-MKADIGIVYAKCT-TYAVAIFCDE +LSAVDNKGHLAVAEISKLIFDYf +>[subseq from] Serine hydrolase n=1 Tax=Pseudomonas zhaodongensis TaxID=1176257 RepID=A0A3M2HY73_9PSED +------------------------------------------------------------ +------------------------------------------------------------ +---EAVARVLNIPTSELKASMEQAYERYYARNLNASTLESYGRLLVKLAQGDLLSESSRD +LLFKDMKIDRYDAYRLEAGLPSEAAFIQKTGTQLE-RACHVGVIEPEKQADTIVIVACAE +ALDEDKEAGAAFEQVGKAITK-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535JFS0_9CHLR +----------ALASLPGEASAFASDAEGRALF-CVNEDEPFPSASVIKLPLVMTLYADAA +RGRLDLDEAAAVG--DRVDGSGVLRHMRDVELSLRDLAMLAIIVSDNTATNRLIERI-GL +DRVGERLREWGCPNTRLARKMYDFEAA-KHGRENVMTARETVSLLLRLHRGECEDRSTSD +AVLAVLEECQD-RTMLRRYLPYGLKVAHKTGTLDE-SRNDAAIV--PGERPALVAAFTRK +LRDTS------------------ +>[subseq from] Uncharacterized protein n=2 Tax=Bacillus TaxID=1386 RepID=E5WSH7_9BACI +---IKAEILDLASCCEGRVAVYIHT--EDGVI-ETNADDVISSASLIKVPILLAGLSQAE +NALLDLNEEAEVKDAARVGGAGVLQAMSKGLMKVIDLMTLMVIVSDNTATNLIIERL-GI +EKINQFIKSLGFNCTELNRKMMDFE-ALKNGMDNTTTARDMVYGMKALAENSLLSGKFTE +KALDILEKQQYKNKLANTMDTEKVKVASKTGELP-GIEHDCAIFTHKGN-TVYAAVLVDQ +LR-SQAAGREVLSAIGSR----- +>[subseq from] Serine hydrolase n=3 Tax=Ignavibacteria TaxID=795747 RepID=A0A1G0X9T3_9BACT +--SLKIKIDSIFKSLEGDFSLAFKEVDNEKNLiLINEKMIFHAASTMKTPVMIEVFKQAA +ENKFNLDDPVEINNESIADGSPYYYKFIGKKKTIYDLVFDMITVSSNLATNILIELV-GA +KNVTETMRSIGANDIQVLRGVED-NKAFQLGLNNVVTAFDLMLIYENLVENKFASDSLTN +EMLNILLQQKH-NSRIPAKLPQDVKVAHKTGSIT-GVGHDSGIVFLSDGRKYVLVLLSKN +LK-DEKAVIEAEAEVSKIIYDY- +>[subseq from] Serine hydrolase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=A0A2L2JWA9_9NOCA +---VTERIRAVFADAGCTGWLHARRCGGAAEI-SIDGRDRVVTASVYKLVLFVAFCRRVD +AGLIDPRAQLTVHPADCTPPTGIAALHDPVTMSRRDLATSMMTVSDNAAADVLLGEI-GL +GAVEDLLDELGLTETRIVGGTADVHRAYDPSYASATTPEEMTRFLHLVWAGGVLSPEQTG +FVRAVMRKQVW-PHRIAAAFPRGVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLAVVDAAIAEAARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga pinensis TaxID=79329 RepID=A0A561I3E3_9BACT +-qKLEQGLRNVIAGFHGDVGIYVRNLRTGHYA-EINADTVFPTASIVKIPILVGVFDKIE +KGELQYHQPLVYRDSAKYGGSGIMQYFKDSSTDLSVLLALMMSYSDNTASLWNQALAGGG +ERINQLMEQYGMHVTRVNSRTAGRQEIWKIYGWGMTTPREMATLMVKIRNGEVISQSASE +RMYRLMTHPYY-DEGAISAIPPYVQAAHKSGAVDE-SRSEVVYVNAPHGE-YVFYVGTKN +IATDDNEASKLIIKVSKYLWDYf +>[subseq from] Beta-lactamase n=1 Tax=Microbispora sp. ATCC PTA-5024 TaxID=316330 RepID=W2EPP6_9ACTN +------AIEQVFRSAGVSGRLHVADIDGGAEV-AVGADEPVVLASVFKVPLVVELHRQAD +RGLLDLAERVRVPAEERTPGPTGLSAMLDGALSLRDLAYLMMAVSDNTAADVVLARV-GL +DAVNAMLAGLGLPGTRVEHDCRGLFAVLSPAHTNRGTPREMTRLLGMIWRDEAASPGSCA +AIRRLMGLQVW-PHRLSSGFPDDVAVSGKTGTLAT-LRNEVGVVEYPDGGRYAVAVFTRS +HGQNQPRADAAVGSAARIAIDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Kryptobacter tengchongensis TaxID=1643429 RepID=A0A656DBG6_9BACT +--TIVSKINQIGKKYGGRLGVSAKNFVTGETI-QINADSLFPTASVIKVPILVELFYKFE +EGKLKKDTLVSLEDSLKYGGSGVLQYFYDGAIKLIDAAVLMIILSDNTATNLVLDCFANL +DAVNNRMKELGLDNTKILNKLMSFETKKKTPEAGYTTPNDMVKLLELLANGKIINPNVSA +EIINIMKNNQD-YEMMKRYLPENIVVANKSGSIDR-MKADIGIVYAKCT-TYAVAIFCDE +LSAVDNKGHLAVAEISKLIFDYf +>[subseq from] Uncharacterized protein n=1 Tax=Dehalococcoidia bacterium TaxID=2026734 RepID=A0A2D6N8M2_9CHLR +-----EALDRIAAQFPGRLGLYIEDLATGANH-EYGAGHRLPTASICKIPVMIELFRQAE +AGLLSLSERRRLSGDISTHGTGLLALLEDEPLTLYDYCRLMIGVSDNMATDLLLDVV-GV +SSVNTTLDALGFVNTRTSMTMGRCHYFQDGPQNNVTAPREMGAILGQLYRGQIVSAPASA +AMISLLKGCQH-RAMIPRHIAPDVAIAHKHGSSSR-IKGDVGIVFLPTGPLIIAALALAS +RGADGNAGADAIAEISRLTV--- +>[subseq from] serine hydrolase n=1 Tax=Psychrobacillus psychrodurans TaxID=126157 RepID=UPI000B874DC2 +--KLVSRIEKLIVPSKGTWGIVLEDLNSGEKW-EHNEQELFYAASVIKLPIMASVYSAVE +RGDLALTDLIILDEQDYVGGSGVIQHFTPGSLPLKDIIMLMIIQSDNTATNLLIDLV-GV +ESIQNTMKEVGMVYSTFLNKLMLSKPNPK--GANCIAAVDISVLLHEMAIGGLVSNKASD +QMVDVMKKQQV-RDCLPEKLPAPWELANKTGWIP-GTRHDVGIFYVGDRE-FIATVLSKD +ED--DLISKRILSQIGEEIYNY- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus firmus TaxID=1399 RepID=A0A0J5WAS1_BACFI +-hTLKAEILTLASCCEGRVAVYIHT-E-DGFI-EKDADAIFSSASLIKVPILLAGLLQAE +KGLLQLEEEVEVTVSARVGGSGVLQAMARDLIKVTDLMTLMVIVSDNTATNLIIELL-GI +EKINQLFKDLGFNNTSLNRKMMDFE-ALKNGIDNTTTARDMAYGIKTLAEQKLLSGKYTE +KALYILENQQFKNKLANTIDEEKVIVANKTGELP-GIEHDCAIFTHKGK-TVCAAVLVDR +LQN-QAAGKEVLSAIGSRI---- +>[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Kryptobacter tengchongensis TaxID=1643429 RepID=A0A656D0A2_9BACT +--TIVSKINQIGRKYGGRLGVSAKNFVTGETI-QINADSLFPTASVIKVPILVELFYKFE +EGKLKKDTLVSLEDSLKYGGSGVLQYFYDGAIKLIDAAVLMIILSDNTATNLVLDCFANL +DAVNNRMKELGLDNTKILNKLMSFKTKKKTPEAGYTTPNDMVKLLELLANGKIINPDVSA +EIINIMKNNQD-YEMMKRYLPENIVVANKSGSIDR-MKADIGIVYAKCT-TYAVAIFCDE +LSAVDNKGHLAVAEISKLIFDYf +>[subseq from] serine hydrolase n=1 Tax=Oscillibacter sp. PEA192 TaxID=2109687 RepID=UPI00135B7625 +------------SSVPGHIGFYYKNLVTGETD-GSRQTELFQAASVIKLPILAAILLEER +EHPGVLQERLLVRDGDKVPGCGALQHISGTQYDIESLCKLMITISDNTATNVLIRRF-GI +EFLNERFRALGLQETKIFRFLFDTEAA-RQGKENLCQPKEIGSLLEEIYHGRCVSANASE +RMRAMLSQQQI-NHKIPSLLPPTVRVEHKTGEDE-GITNDVGILY--GREPCVLVFVSNE +TD--VPAFEQVIRTVS------- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium QH_9_67_14 TaxID=1919102 RepID=A0A2T2SNQ1_9BACT +----------------ASVAVAVR--TRAPTF-DWHADRVFHAASTMKVAVLIETYRRVE +RGALALDDALAVENCFRSAGGGVFYDHLGGALPVRTLTERMVTCSSNLATNLLVERL-GA +DAVERTARRLGAGTMRIRRGVEDRA-AYRAGLSNTASARDLAALMNALMRGEAVSPQADR +AMIETLAGQRY-NSMIPAGLPSDTRVAHKTGWLD-ALHHDAAIVCPPGEVPYVLVVFTEG +IRAH-SRSARLGAEIARAAH--- +>[subseq from] serine hydrolase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI00126245E9 +------------------------------------------------------------ +---------------------------------------------------LVLEKIGGP +AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ +QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ +TEATFDERNAAIVTIGKSIFDTf +>[subseq from] Beta-lactamase CTX-M-1 n=1 Tax=bacterium HR26 TaxID=2035421 RepID=A0A2H5YVF2_9BACT +--EMTSTVREAIERVPGRVNLLARDLDRDWEL-SYRAEVPVTAASVIKLLILAEAYRQFE +TGEAHPDEPVRVEPESWVGGSGVLRWLRPGLLTLRDLAVLMVIVSDNTASNLLIDRL-GF +ECINGLARRLGLEQTVLARKFLGRA-AQGNEPENLVSARDMAALLAALELGQIVPDPLLQ +DLRQILKAQQF-RDVIPGRLPAEAVIGNKTGSLP-GHAHDAAIIWAPAGR-LVLVLLSSG +LV-DQELGRRALCDLALACYRTw +>[subseq from] hypothetical protein n=1 Tax=Paenibacillus sp. SSG-1 TaxID=1443669 RepID=UPI000B7FB254 +-----------AEKDGIRMSVGIRDLSGHETL-LLGSREPYMPASTIKLAVVSALMKQVD +RGELSLADQVRVTPEDVVGGSGSLQTSFPQDLTLERLARLMITQSDNTATNVLIDKV-GM +DRVQQLMDQLDLRTMHLGRKMFAAA--PSPAQDNYIDAADLTELLGQIYQGSFLSVSSRN +QIIAWMARQEV-NTKFGAALP-NAPIAHKTGENAN-VTHDAGYFLVPGHE-LAVSVLLQV +TTEAQRIGNPIVQKAARAIYS-- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus sp. YIM 77859 TaxID=1540221 RepID=UPI000553364D +-----------ARGYGGEVGILITDLAGRELY-ALQADRIFPAASTIKVPLLILALEEAQ +AGRLELGERVTLRAEDRVPGAGVLHELGAGLLTWEDLLTLMIVVSDNTATNLVMGRL-GI +ERVNTWLEERKLVGTRLVGLLEQQNAAQRRGERNHTTPRDQAALLGALTRGELLDPAHTE +RALAILTRQQF-RDLLGRHVPRDYRVASKSGELR-GLHHDVGVLFTP--RPLVAAVLSEG +GL--------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8G1W3_9BACT +-qRLQASIERTTRSVNATWGIWIKSLDTGEEI-AVDADRQMETMSTIKIPLMVEAFEQIK +ADTFKLTDKYTLVAEDIRPGTGIIQRLDPGALTVKDLITLMIIVSDNTATDVLYRMVGGP +AVVTRRMETMGLKKTQAVTNGAGWFAREGKHPFGLSTPREMGSLLEQMERGTLVDKAASD +AMLRIMRGQLY-RTRIPRYIT-GFTIPHKTGDFLPYVGDDVGMLEGQGK-TIIVSIFTAN +HFGSGEALENAIGLVAKEAADYf +>[subseq from] serine hydrolase n=1 Tax=Pedobacter indicus TaxID=2292082 RepID=UPI000E4C6D51 +-kKLQKTLEELTKNHQGDVGVYVYHLKKHKEV-AINADTIFPTASVVKVPILIGLFKKIS +DGKYTLNQPMVYDDSRAYGGSGLMQFYKDSSTDLRTLASLMITYSDNTTSLWCQELAGGG +AEINKVMADIGLKDTRVNSRTEGREKIWEIYGWGQTTPREMASLLIKIRNGELIDKVASE +QMYRLMTSGFY-VDNAASQIPPYVQKASKTGAVD-ASRSELIMVNAPHGD-YVLYIGTKN +NKDRDNEASQLMRDISAAVWHHf +>[subseq from] Serine hydrolase n=1 Tax=Ignavibacteriales bacterium CG_4_9_14_3_um_filter_34_10 TaxID=1974044 RepID=A0A2M7ZFJ8_9BACT +------------NQIEGDKAVFFLNLETGEEI-KFNEKEKFHAASTMKVPVMLELYRQAS +VGLFSLIDSIIVKNESIADGSSYKYDLIGKKLTVYELNHRMITKSSNLATNILIEFV-GV +DNIMKTMKSIGANDIRVLRGVEDIPA-YRKGMNNTTTAKDLCLVLKSILDYKVVNEKLSN +EILSVLEAQEH-NDIIPEQLPKNVKVAHKTGWIT-GVMHDAGVVILPDGRKYILVLLTKN +LT-NEEKSKKILQEISLEFYKYf +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A6B1CLJ6_9BACT +-----AALRQIAAAFDGRMGWHIEDLATGQVH-QYRADERFPTASVIKIAVLVELFRQAE +AGRLSLDGRHRLRGDISTHGSGVLQIAQDEPLTLRDYARLMMGISDNIATDFLMGLL-GL +DQINATLDRLGCANVRAAATMGRYHYFGGSLENNVAAPGELASLLAAIYRGQVVSAAASK +AMIELLKTGRD-TRMIRCYLQPDVVVAHKYGSSGI-IKGDAGLVFLPAGPLVVVAFALAR +DD--GSAAAEAIAQVARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Marinobacter salicampi TaxID=435907 RepID=UPI0014092E56 +------------------------------------------------------------ +----------------------------------------------------------GN +ARYEMLLEKLGISKAQADASVQEAFERYYKRGINSGNLEAFGQLLERLVDGELLDDSHTE +RLLGYMAGITTGDNRIAGGLEDDVRFAHKTGTQV-ARSCDIGVLNPQVPDQAVVVAVCAE +DYDALSDAEKAYQAVGKALT--- +>[subseq from] Serine hydrolase n=2 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A3D4T9F6_9BACT +-hRLTKQIQELIQGFRGETGVYVHDLEKNKVV-AINADSVFPTASMVKIPILVGVMDQIS +KGQLKYHQKLTYKDSLLYAGEDILGSFKSGEIELSKVMMLMLTTSDNTASLWLQSLGGTG +THINALMDSLGLQQTRVNSRTPGREANRNQYGWGQTTPAEMAKLMEMIVNKKVISAAASE +QMLRLLGRNYW-DEEALSQIPAGVFVASKNGAVN-ASRSEVLYVNGDDA-RYIFCICTKN +NQDQNNEAWVLTKKLSALLWKYy +>[subseq from] Serine hydrolase n=2 Tax=Oceanobacillus halophilus TaxID=930130 RepID=A0A495A1T4_9BACI +------------SEVSENFSICIHS--SNGNI-TINAENQKKAASIVKLFILVEAFRQKE +KGNLSFDDTVSIDKKRMVGGSGIITNLTESHYSYRNLIELMIIVSDNTASNVLLDKL-GI +NEINNLANQIGCEQTIITRKFMDYHAA-SKGFENYTSASDVCKLLQLLPKNNILSDNSRE +QILDILAKQQF-NHKLPSYFPEGTTFYHKTGEIT-GAEHDAGIFKNKQE-MIPIAVLSDG +WEEN-GRAQRYLAEIGRLIYKY- +>[subseq from] Beta-lactamase class A n=1 Tax=Armatimonadetes bacterium DC TaxID=1661583 RepID=A0A0S4PM12_9BACT +--KLKARLDAICEKFRGVMGYSLFHKRYQHRI-HRLGDEIFPTASTIKVAVMSKAFEEID +AGRLGYTEKIPITPDDLRDGSGLLQFFKENQVEVRMLIHLMITVSDNTATIMLARRL-GT +VEVNKHLQRLGLKDTRLLALHPELKAYREKWGMGMCTPNEMVALLDAILTNRAGTPAACE +RMIRIMAHQYY-DDLIGSSVPPWVVCATKSGAISR-SRSDVGIVFALSGT-YILAVYTKE +AEAPDNEGEVAIRAVAHEVWKFy +>[subseq from] DUF3471 domain-containing protein (Fragment) n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A4Q5RDR7_9BACT +------ILAELDKHPEGNFAIAYKDLGNGQTL-FLNERAVFHAASTMKTPVLIETYKQAA +AGKFRITDPILIKNESIVDGSLYSYEKLNSKLSIYEVLHRMITRSSNLATNLIIDLV-GA +DKANATMRLLGAKDIQVLRGVEDDK-AFEKGLNNTTTAYDLMIIMEALATGKVVSESASK +EMIRILMDQQF-HEKISKKLPPEVKVASKTGSII-AVSHDSGIIYLPDGRKYVLVLLSKG +VR-DLDDVNNTLANVSRLIYDY- +>[subseq from] hypothetical protein n=1 Tax=Paenibacillus favisporus TaxID=221028 RepID=UPI0013D1B742 +------------EKDGIRMSVGIRDLSGHETL-LLGSQEPYMPASTIKLAVVSALMQQVD +RGELSLADQVRVTPGDVVGGSGSLQTSFPQDLTLERLARLMITQSDNTATNVLIDKV-GM +DRVQQLMDQLDLRTMHLGRKMFAAA--PSPAQDNYIDAADLTELLGQIYQGSFLSVSSRN +QIIAWMARQEV-NTKFGAALP-DAPIAHKTGENAN-VTHDAGYFLVPGHE-LAVSVLLQV +TTEAQRIGNPIVQKAARAIYS-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus kribbensis TaxID=356658 RepID=UPI000411D4E8 +-----EDLHKVLQTENGRISAAVEI--DGQLF-EHNVSLRMPSASLIKIPILLTAYRESE +RGSLHLDRPIQVPASSRAGGAGVIQALSDGILTVKDLLTLMIIVSDNTAANICIDLL-GM +RAINRTIDELGLSQTLLGRKMMDWA-AITEGRNNYTSAGDMLLCLKAITAGHYLSEESRN +EILSILEKQQF-QDKLPALMDNRVRAANKTGELP-GVEHDCAIIRFKDRT-AYAAILIEG +LRN-KIKGKKIISNIGKIIYD-- +>[subseq from] hypothetical protein n=1 Tax=Paenibacillus terrae TaxID=159743 RepID=UPI00119D6068 +-----------AEKDGIRMSVGIRDLSGHETL-LLGSQEPYMPASTIKLAVVSALMQQVD +RGELSLADQVTVTPEDVVGGSGSLQTSFPQDLTLERLARLMITQSDNTATNVLIDKV-GM +DNVQQLMDQLDLRTMHLGRKMFAAA--PSPAQDNYIDAADLTELLGQIYQGSFLSVSSRN +QIIAWMARQEV-NTKFGAALS-DAPIAHKTGENAN-VTHDAGYFLVPGHE-LAVSVLLQV +TTEAQRIGNPIVQKAARAIYS-- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7SWH2_9BACT +--ELEARFAELEALSGARLAIAISDFESGHDF-AYHADRWFHAASTIKLAVLVGVYGAIH +RGDLLPQSRVHVRNRFLSAGSPYRHREIGRTLRVSELAEHMIISSSNLATNLLLDLV-GL +DVLQRTLEEFGLQGIDLRRGVED-EAAFEHGISNRVTARGLVGLLRLMGEERAFTPELSR +QMLDILHRQQF-RSGIPAGLPREARVANKTGDIST-VAHDAGLVYLPDRKPYAIAVLTEW +EP-SATGRSTTIAAASYI----- +>[subseq from] Uncharacterized protein n=1 Tax=Prevotella sp. P3-120 TaxID=2024220 RepID=A0A255SFN6_9BACT +---------------------------NGELYcGHQEDSAFAMHSVMKFPQALYVADYLH +KKGLTLSDSVLVNKDSLDAWSPMLSIFEGMRFTFAELIEWSLKQSDNNACDLLFASCGQP +DAVEKYIHTLGFKDIHVQLTEKEMKKNPHRAIENSATPKEMARLLEWFYLHRD-DNKNLS +FIWDTMADCNTGQQRIAAVLPKDGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFLQK +SKEEKEVAE-------------- +>[subseq from] serine hydrolase n=1 Tax=Collinsella aerofaciens TaxID=74426 RepID=UPI0010FF0E3B +--AIQQDIEALAEPYGGSVSVYAAALDLDGEV-AVVPDARRVAASIIKLPILACALETVA +AGELSLDEQITVTQQDIVGGSGSIQSRGAGVYSVDELLRVMIAQSDNVAANLVIGRL-GM +DAVNETCAALGLAQTVLARLMMDAEAQ-AQGRENYTSARDAAAVLQRLAAGTIATPELCE +RARGYLLAQED-ARGIVEGVSGVVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD +LD--REQALALERDISSVIY--- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridium sp. SCN 57-10 TaxID=1660094 RepID=A0A1E4LJ99_9CLOT +--------RSYADKTSAKLGFGFCDLASGASF-FLHGDDAFPAASAYKVWILAEVLRGAE +AGGYSMQDRLTLTREVKSLGSGVLYDLGEGLPTLLDYATLMMILSDNTATDVLFGYVGRD +NIKQNILDRYELAQTKCDWTCARLIEACTTEENDQTSPQDAVKTLRMAYEGTLVSPTVSA +EMLRIMKLCQT-NSRIPKHLPRGTEVAHKTGTIDR-VANDMGIVYTPKGD-YVLTLFYNG +NLANEED---------------- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8LAV3_9BACT +--SLQTKVTAMAAQHHGKLALYAANLKTGESI-AIDPDTPVATASVIKLPLLFEAMEQVK +SGKHKLTDKIMLQKDDIVQGSGILQFFDTPLISLKDALTFMIIESDNTATNLVIDQV-GI +KNVNDRIAQIGLKDTYLYKKVFKPATDQKKFGLGKTTAREMAKVMEAIVRCDLQDQKLCD +DMLYMLRNQQY-RNLVPHYIETSSFIANKTGSLDE-VRNDVAVVYSKHG-PIIISAFTYD +NANNDNAAEMLVAHIAKLIMDAw +>[subseq from] Beta-lactamase n=1 Tax=Cyclobacterium amurskyense TaxID=320787 RepID=A0A0H4PA18_9BACT +-kQLENEIRNLMDSVEGDFGLAFRLLDDAKEL-FINEKEVFHAASTMKTPVMIELFKQEK +AGNFSLQDSIVIRNESILDGSTFSYSRIGEKGSIYELMYEMIVNSSNLATNLLIEMV-AA +ENVNQTMRDLGANDIQVLRGVEDLK-AYDAGLSNTTTALDMMLVMEAIAENKVIGAK--- +NMMEILSDQHF-NGLIPKYLPKTAKVAHKTGSIT-GVQHDAAIVDLEDGSRYVLVVLSKN +LQ-DEEAGKACIARVSQLIYAY- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga ginsengisegetis TaxID=393003 RepID=A0A1T5P8I8_9BACT +-hKLEKGLKDIITGFHGDVGIYVKNLRTGRYA-AINADTIFPTASIVKIPILVGVFDKIE +KGELKYHQPLIYRDSIKYGGSGLMQFFKDSTTELSVLLALMMSYSDNTASIWNQSLAGGG +QRINELMEQYGLAVTRVNSRTPGRAEIWKVYGWGMTTPREMATLLVKIRNGEVISKAASE +RMYRLMTHGYY-DETGLSAIPPYVQAAHKTGSLD-ASRSEVILVNEPRGE-YVFYVGTKN +NKTDDNEAQVLIKNVAAYLWKYf +>[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas suwonensis (strain 11-1) TaxID=743721 RepID=E6WP80_PSEUU +---LEQRLQAIDRSLGGGIGVHVLHMERNESY-GYRASEPWYLASGVKVPVAIAVLREVD +SGALSLDTELVLRADDFVDGDGATNRHRPGDLAVSWLLEQMLVHSDNTATDVLIRTV-GL +PAVNNVAAELVDSGLHI------------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas suwonensis (strain 11-1) TaxID=743721 RepID=E6WP80_PSEUU +------------------------------------------------------------ +---------------------------------------------------------AGP +ARVRKLAQLLGVPLEELRQDLASAFEAYYATGANSAALVDYGRMLASLANGEVLGGDTNR +WLLEVMLRVQTGQRRLRAGLPAGIAFAHKTGTQFH-RTCDSGIAMQPRGSRVVIAACVRG +VG--TAAGERALRRIAAAITE-- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=UPI00033C6BE3 +-eKVNADLDQTITPLRGINSVYVSPVDSNETI--VRNNHVQRSASAIKLYILVTAYAMDK +EGLFNLDEKHTIESDEKVGGTGVIRELPDGTLTYREILNDMITKSDNTGANIMIDALGGF +TIINNKIKAIGTQNTKLQRKMMDTA-ALEDGIDNDTSVQDMGETLKKLYNHDLVSKTADD +EMLAILANNQN-HTKLPASLPSEAKVYNKTGEYDYGVQNDAAIIANDKGA-FVVVVLSQD +GNE--QQQISAMSQLGSALY--- +>[subseq from] Beta-lactamase n=1 Tax=Solibacter usitatus (strain Ellin6076) TaxID=234267 RepID=Q01Y38_SOLUE +--PLQDAVRERIGNFQGTVSLYAKNLDTGASV-GIREALPVRTASTIKLPILLAVTDQVA +AGKAKWTEMLTVRPQDKVSGSGVIGAELSDGLPLRDVVHLMIVLSDNSATNMILERF-TA +DAVNAYLDKIGIKTTRSMRKVRGDGTENQKYGLGVSTPRDMVTILEKLERGEVVSPEASK +EILAVLKRCQD-NTGVRRKLT-GVSIANKTGALD-ALRSEVALVYAKGG-RIAIAITVDD +MPTPDNAGSLLIADLARILVD-- +>[subseq from] Abhydrolase_3 domain-containing protein n=1 Tax=Prevotella sp. P2-180 TaxID=2024224 RepID=A0A255TQ30_9BACT +----------------------------GDLYcGHQENSVFAMHSVMKFPQALYVADYLH +KKGLSLSDSVLVHKDSLDAWSPMMSKFEGARFTFAELIEWSLQQSDNNACDLLFASCGQP +DAVEKYIHTLGFKDIHVQLTEKEMKKNPHRAIENSATPKEMTRLLEWFYLHRN-DNKNLS +FIWNTMADCNTGKQRIAAVLPKGGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFSPK +SKEEKEVAEI------------- +>[subseq from] Beta-lactamase class A n=2 Tax=Bacillus oleivorans TaxID=1448271 RepID=A0A285D5S2_9BACI +----GEKIKEIKEQCAGRLSVLI-DI-GEQKI-EADSEQIFLSASLIKIPILIAGFRQVE +QKILDPAELIYVPRDEKVGGSGVLATFSDPVLTVRDLLTLMITVSDNTATNILIDLI-GL +EAIQSCIKDLDLKSTILNRKLMDIESK-EKGIENSTSASDIVNCLKAIHRGSFLSHNSTQ +AVLSIMAQQQF-THKLPAYVDEKVKVFNKTGELD-GAEHDCMILTFGEKT-AYVAVLTDQ +LE-HNESGRQTIRQIGKHVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Ignavibacteriae bacterium HGW-Ignavibacteriae-2 TaxID=2013809 RepID=A0A2N1VZV6_9BACT +-nQLKTKIEQQIKNTQGSYAIAFMSLYNDDKM-YLNEREQFHAASTMKTPVMIEVFKQAE +ENKFNLQDSIILKNESIVDSSLYSYKYIGKNRTIYQLVYEMITVSSNLATNILIDLV-DA +RNVMQTMKLLGALDIKVLRGVEDIK-AYELGLNNTTTALDLAIIFKSLYQKKVISETACD +EMLNILFNQKH-KSILPFKLPADVKIAHKSGSIT-GVIHDSGIIYLPDGRAYVLVLLSKD +VK-DEAAGRMFLQDISKQIYDY- +>[subseq from] serine hydrolase n=1 Tax=Nocardia sp. BMG51109 TaxID=1056816 RepID=UPI0004642E59 +---------------------------SAAEI-SVGGDERVVIASVYKLALLVAFCRHVD +AGRIDPTARLTVLPADCTPPTGIAVLRDPVTMSLRDLATSMMTVSDNAAADVLLGET-GL +GPVEELLNDLGLTRTRIVGGTADLHRSLVRDTDTHTTAEAFATLAE-------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Trichococcus sp. ES5 TaxID=872292 RepID=A0A143Y8M2_9LACT +----------RLESLPGKISCYYKDLVDGDSF-SYNSAEPMHAASIIKLFIMVEAFRRFE +AGSLDPKQKVAIRDHDRVPCGALTYLHDGIEVTVIDLVTLMIILSDNTATNVLIDLL-GF +AAINTTIHRLGYSETGLLRKMYDTEKS-AKGIQNLITAEEAGDLLERLHRGEIVSDQASA +QMLAILANQRL-NSKLPFYLKPTPKIAHKTGEDT-GITHDVGVVYPPAGHPFVLCFLGNG +T---------------------- +>[subseq from] Serine hydrolase n=1 Tax=Runella sp. HYN0085 TaxID=2259595 RepID=A0A344TSY9_9BACT +-----------------------------------GPAESVPSASIIKIPILVELMEQVK +AGKVNLDETYTLVAADKTGGSGVMASYPDGQMSLKEVARLMMIASDNTATNIFIRKL-GR +EKINDRMKLLGLASLQLNRVMMDTAA-VSRGIDNYVTARDINALLRLIYGHKVATPNLCE +QMMEFLFENRD-TVTLPRLIPKTIKIAHKTGGLTY-VRGDAGIVFAA--TPFVISVFVRG +TP--EKNAEKIIGEIGKICFKIf +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5UN25_9BACT +--SLRDAVEKIAGESKARVAVALLDFDSGLRF-SLAGDRWFHAASTIKVAVLLAVFRAVD +EGRLRLDDSLHVRNRFISAGFPFRYQAIGRTVNISALAEGMIAASSNLATNLLLDLV-GV +EYARNVLREAQVSGVELRRGVEDH-AAHERGIDNQVTADGLLTLLCA-VRGNFLSNESRE +HAIRILLAQRF-KSMIPAGLPAHATVAHKTGEIST-ACHDMGIVYLPERQPYIAVILTEF +DS-ELDGRRETVAAISEVIH--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces albireticuli TaxID=1940 RepID=A0A2A2DBW4_9ACTN +----RGRVRAAFAEAGVTGWLHAVDIDSGDQL-DAGADQPVVTASVHKLCLLVALHQQAE +AGRLDLSEQITCPPRDRTPGPTGLAAMLDDVLSLRDAAYLMMAVSDNTAADLILERV-GL +DAVNHTTRRLGLTRTRAVHTFREFLTVLDPAATNRSTPRDMTRLLTAIWRDEACAPEHTA +AMRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA +ASAVLPPADAVIGAAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7VA16_9BACT +-----DQLKKLADAHKGKVAISLKHLKTGESW-ALNSQTPMPTASLIKFPVMIEAYRQAA +EKKVSLDQMITLKKEDKVPGAGILTYDFTPGLALRDAIRLMIKFSDNTATNLVVDVI-GL +PSTAKTMIAMGYPNTQLHSKVYKRETSIALERSGSTTADEMIRLFEELNRGKLVSPEASK +EMYAHLLTCDD-NEKFPKFLPHGTKIAFKTGSVD-ASRTASGIFETASG-PVALCVLTTD +NEDKENAGNLLCAHAAKIVFDHy +>[subseq from] serine hydrolase n=1 Tax=Nocardia caishijiensis TaxID=184756 RepID=UPI00082D9F69 +---AADRIRAVFADAGCSGWVHARRCDSAAEI-SVGGWDRVVMASAYKLLVCVAFFREVD +RGRIDPTDRLTVDPADCTPPTGIAALRDPITLSRRDLVASMMTVSDNAAADVLLGEL-GL +AAVTDLAAELGLTETRVIGGTADQHRAYDPAYASATTPADMTTLLTQLWSGRVLSTQSTE +FVRSIMRDQIW-PHRIRAAFPRDVVVAGKTGTIGI-IRNEVAVVEFAGETPVAVAVFTRA +ARPDLPVVDAAIGEAARIAVT-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured Oscillibacter sp. TaxID=876091 RepID=A0A1C5LMP8_9FIRM +-------VKRQLSSVPGHIGFYYKNLVTGETD-GSRQTELFQAASVIKLPILAAILLEER +EHPGVLQERLLVRDGDKVPGCGALQHISGTQYDIESLCKLMITISDNTATNVLIRRF-GI +EFLNERFRALGLQETKIFRFLFDTEAACQG-KENLCQPKEIGSLLEEIYHGRCVSANASE +RMRAMLSQQQI-NHKIPSLLPPTVRVEHKTGEDE-GITNDVGILY--GREPCVLVFVSNE +TD--VPAFEQVIRTVS------- +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5ZR96_9BACT +---LHEELETLALRNKARIGVALHDLETGFRF-SLCGDRWFHAASTIKVAVLLAVFRAAD +EGRLRLADSLHVRNRFFSAGSLFRYATIGRTAKISALAHAMICGSSNLATNLLLDFL-GV +EYARTVLREAQVDGVELRRGVEDH-SAHEQGINNEATADGLLKLLSAI-RGDFLTPESKR +EVIRVLLEQRF-NSMIPAGLPPHATVAHKTGEIST-ACHDIGIVYLPEREPYIAAILTEF +DP-DTEGRRETVAAISEAIYR-- +>[subseq from] Serine hydrolase n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A2N6AGB0_9FIRM +-------VKRILKDIPGQTGFYYKRLDGSEIV-AFNEDRIFYAASLIKIPILIEAFNRVR +LGEMDFDKKYEVRNSDKVPCGALAYMHDGLEVTFRDLCVLMIIHSDNTAANMLIRIL-GM +DRINQTLIDREMYMTRLNRLLFDEE-ASAQGLENTAVLDELAMLFEEMHNGRLVSRKASI +EMLDIFKMQRL-NSKIPRLLPKGVPIAHKTGEDQ-GITHDIGIVYA--RKPFLIGFMSNN +TD--VVAMENAISEISRFAYK-- +>[subseq from] hypothetical protein n=1 Tax=Lactobacillus xiangfangensis TaxID=942150 RepID=UPI00070F9E10 +---VKQVVDQQMVALGGTSSVAVEPVTNGAVV-SHNRSQR--AASVIKLFILTTVYQQVA +DKKLNLDNTYQLKSSDKVGGTGTLQTLPNGSLTYKEITKRMIDESDNTAANIMIDTVGGL +RVVNQEISRLGLSQTKLGRHLMDTNA-LQAGKDNYTSVEDVAKLLKQMYNHQLVSKQADK +QMLAILKQNVN-HTKLPHDLPSDAIVYNKTGEYQYGVQNDAAIIKNRHGA-FVVVVLSQD +GKEQ--TQVAAMN---------- +>[subseq from] Beta-lactamase class A n=1 Tax=Deinococcus peraridilitoris (strain DSM 19664 / LMG 22246 / CIP 109416 / KR-200) TaxID=937777 RepID=L0A686_DEIPD +----PKTIHALLSQHPGKVAIRVESLEGQLLL-SESDTHVFPSASIIKVPLLVRALQRVE +RGDFQLHDRIIMRSEERVTGSGILRDLDGDLLTLRDALTLMIIVSDNTATNLVIEQL-SI +DDVNAFLADEGMHDTALQVTPNRFTARQRAGERNRTTARDMTTLLGKLARGELLKPELTK +IALDILARQHY-KDILGRHVPTDYRVASKTGSLP-GVRHDVGIVWTP--EPLVLAVLSEG +GHHPDNHEVQLLARVARALLT-- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5RG96_9BACT +--TLAEELERLTAESKTRAAVAVHDLESGLRF-SLRGDRWFHAASTIKVAVTFAVFRAAD +DGWLRLDDSLHVRNRFISAGSPFHYGLIGRTAKVSVLAKEMISASSNLATNLLLDFV-GV +EYARKVLQDAQVSGVELRRGVED-HAAHEREINNEVTASGLLTLLSAI-RGDFLSNKSKE +QVIRILLEQRF-KSMIPAGLPPHATVAHKTGEIST-ACHDMGIVYLPERAPYIAVILTEF +DS-EREGRRETVAAISEAIYR-- +>[subseq from] Uncharacterized protein n=2 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5ZDG2_9BACT +--TLNEEVERLSAESNARIAVAAHDFESGLGF-SLRGERWFHAASTIKVAVLLAVFRAAD +EGRLHLDDSLHVRNRFISAGSPFRYQLIGRAAKISTLAEGMIATSSNLATNLLLDFV-GV +EYARHVLRDAQVDGVELRRGVEDH-AAHDKGINNEVTADGLVRLLSAV-RGDFLSNESKE +QAIRILLEQRF-NSMLPARLPVHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EGDGRREIVAAISEAIYR-- +>[subseq from] serine hydrolase n=1 Tax=Planobispora rosea TaxID=35762 RepID=UPI00083A0E19 +------EFDGLFRAAGVTGFLYAVDVDTGAEV-AYGADEPVVLASVFKIALLVEFFRQAD +RGALDPAERVTVMAGRHTPPTGVSAMTDDVTMSLRDLAYLMIAVSDNTAADTLIGRV-GL +GAVNTMLDGFGLARTRVEHDCATLFTVLDPARTNRSTPRETARLLAMIWRDEAASPESCA +WMRRLLGLQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEAGVVEYPDGGCYAVAVFTRS +TAQNQPRADAVIGTAARAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus furfuricola TaxID=1462575 RepID=UPI000F7B6427 +---------------GSTTSAYFYDLSSKQSA-TFGTDKQQRAASDIKLFIMATVYQSVK +DGKFYLNEKYALKDTDKVGGSGALQGMASGTIYYQDLLKYMMTQSDNTASNILLDKVGGI +SAVNNEIKKLGLTNSVMQRKLMDTKKL-TAGQDNMTTAKDLGKFLTKLYHHQVVSETADS +EMMRLLLQNTN-HSKLPAQVASDVKVYNKTGEFSYGVQNDAAIMEKGGK-AFVIVVLSQN +GTEATQ----------------- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus xiangfangensis TaxID=942150 RepID=A0A0R2LZV4_9LACO +---VKQVVDQQMVALGGTSSVAVEPVTNGAVV-SHNRSQR--AASVIKLFILTTVYQQVA +DKKLNLDNTYQLKSSDKVGGTGTLQTLPNGSLTYKEITKRMIDESDNTAANIMIDTVGGL +RVVNQEISRLGLSQTKLGRHLMDTNA-LQAGKDNYTSVEDVAKLLKQMYNHQLVSKQADK +QMLAILKQNVN-HTKLPHDLPSDAIVYNKTGEYQYGVQNDAAIIKNRHGA-FVVVVLSQD +GKEQ--TQVAAMN---------- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Gemmatimonadetes TaxID=234665 RepID=A0A1Q7R3J8_9BACT +---VRERLAARVAQAPATVGLYYRSLTHPDSL-LLDANVRFHAASTMKLPVLIQVFRDAD +AGLLRLDDSLTVHVVSLVDASPFDYGRVGRPASVRDLLELMITRSSNLATNILVERV-GA +GRAQASARALGAWSIQVLRGVEDGK-AYRAGLNNTTTARDLGVLLAAIAQNRAASPASCR +EMLRILEAQEF-NEGIPVGLPPGTRVAHKTGWIGEVVYHDAAVVYRSSGGSYVLVVLTGG +IKQD-SVAHNLVADLSRLVY--- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudoxanthomonas taiwanensis J19 TaxID=935569 RepID=A0A562DJ30_9GAMM +--ALEPRLRAIEAALGAGIGVYVLHMERDESY-GYRAGEPWYLASGVKVPVAIAVLREVE +RGTLALDTPVVLRADDFVDGAGATNRHRPGELALSWLLEQMIVHSDNTATDVLIRTV-GL +AAVNRVAAELVDARLRIT------------------------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudoxanthomonas taiwanensis J19 TaxID=935569 RepID=A0A562DJ30_9GAMM +------------------------------------------------------------ +---------------------------------------------------------AGP +ARVRKLAALLGVPPEQLRQDLAAAFEAYYATGANSATLVDYGRMLATLADGKALGAEATG +WLLERMLRVETGHRRLRAGLPPGIAFAHKTGTQYR-RTCDLGIAMQPDPARVVVAACVRG +IG--TAAGVHALQRIAAAI---- +>[subseq from] Beta-lactamase class A n=1 Tax=Paenisporosarcina quisquiliarum TaxID=365346 RepID=A0A1H8FJN3_9BACL +-eKLVSRIEKLIVPSKGTWGIVLEDLNSGEKW-EHNEQELFYAASVIKLPIMASVYSAVE +RGDLALTDLIILDEQDYVGGSGVIQHFTPGSLPLKDIIMLMIIQSDNTATNLLIDLV-GV +ESIQNTMKEVGMVYSTFLNKLMLSKPNPK--GANCIAAVDISVLLHGMAIGGLVSNKASD +QMVDVMKKQQV-RDCLPEKLPAPWELANKTGWIP-GTRHDVGIFYVGDRE-FVATVLSKD +ED--DLISKRILSQIGEEIYNY- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI000D492D05 +------------------------------------------------------------ +------NKTVTIKESDIVAYSPVTERYVGKTMTLHQLISAAMLQSDNTASNIIMEQLGGL +DQISSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHSLQQLLTTDAVAPQQRK +FLQNLMFNNETGDSLIKKGVPDSYKVGDKSGQGTYGTRN--------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6K4P1_9BACT +--TFNEEVERLSAESKARIAVAAHDFESGLGF-SLRGDRWFHAASTIKVAVLLAVFRAAD +EGRLQLDDSLHVRNRFISAGSPFRYQSIGRTAKISTLAEGMIASSSNLATNLLLDFV-GV +EYARRVLRDAQVDGVELRRGVEDH-AAHDRGINNEVTANGLVSLLSAL-RGDFLRNESKE +KAIRILLEQRF-NSMLPARLPPHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EGNGRREIVAAISEAIYR-- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Verrucomicrobia (miscellaneous) TaxID=417295 RepID=A0A1Q7TDQ2_9BACT +-----------------ATAVSVHDLESGLRF-SLRGDRWFHAASTIKVGVLLALFRAVD +EGRVRLDDSLHVRNHFFSAGSPFQYQAIGRTAKIAALAAGMITASSNLATNLLLDFL-GV +AYARNVLRDAQVQGVELRRGVED-HAAHEKSINNEATADGLVALLSAL-RGDFLRSESKE +QAIRILLEQRF-NSMIPAGLPPHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EREGRRETVAAISEAIYH-- +>[subseq from] serine hydrolase n=1 Tax=Steroidobacter sp. JW-3 TaxID=2497877 RepID=UPI00101C7ADA +---LSRLLEAELSRLPTRSGIYVKHLGTGEEA-SVRGNDEFESASTIKLATMVLAFRMAD +ERKLDLSQRYVIKPADYRGGSGIFRFHDPGMPTLRDIITQMVITSDNTATDIMIARVGGK +EVVNRFLRDAGYQVLRQNNTTLEFFRSAKANWFGWATPREMGRLLESIELNTAASKASCE +EMKRILLAQQSGIIKLPHYLT--VPIGHKTGETGT-VTNDVGMIYAHSGT-IVISFYNVE +LAGPRAETEDGMGRVARTVVDYf +>[subseq from] serine hydrolase n=1 Tax=Nocardia higoensis TaxID=228599 RepID=UPI000688466E +-----------------------------AEI-SVGGHARVVTASVYKLVVLIAFCRAVD +AGTIDPAARLTIDPAECTPPTGIAALHDPVTMSRRDLATSMMTVSDNAAADVLLGEV-GL +GAVEDVLTDLGLTETRIVGGTADVHRAYDPAYTSATTPEEMTRLLRALWSGRVLSPEQTA +FVRAVMAKQVW-PHRITAAFPRGVTVAGKTGTIGV-IRNEVAVVEFPHEYPVAVAVFTRA +ARADLPVVDAAIAEAARIAVT-- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium daejeonense TaxID=371142 RepID=A0A4U9K0N3_9SPHI +-kSLEQKINQAIEGFQGDIGVYVKHLKKNKEV-AIHADSIFPTASIVKVPLLVGVFQKIK +NGELRLDQKFLYRESRAYGGSGLMQFFKDSTTDLATLIGLMLSYSDNVTSIWCQELAGGG +QTINPILDELGLKNTKVNSRTPGREEIWKKYGWGQTTPREMSKLFELIREGKVVSSEHSD +KMYRFLKNQFY-NERSLSQFPAIINMISKTGSLDD-ARGEIVLVNAPHGD-FVFTILTKN +NKTNENEAENLTRKIANIIWNHy +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. J33 TaxID=935836 RepID=UPI00047C2A47 +-hDLEAEVLELACSCKGRISLYIET--EEGII-QKNSDEIFSSASLIKVPILLAGLSQAE +KGLLQLTEELEVADHARVGGSGVLQTMSKGLLSAIDLMTLMIVVSDNTAANLVIDLI-GK +ENINGWIKGCKLNSTELNRKMMDFE-ALKKGFDNKTTARDMANCLKSLAEHSLLSGEHTD +LALRILDAQQF-KNKLANYIDENVQVASKTGELP-GVEHDCAIFTRKGR--MAIAAVLAD +QLKDQEAGREVLSSIGRRICR-- +>[subseq from] zinc_ribbon_2 domain-containing protein n=1 Tax=Lactobacillus allii TaxID=1847728 RepID=A0A1P8Q5U4_9LACO +---IKQVINTNLSGLKGTTSVAVASTTNQAKV--VQNNQSQRAASLIKLFILITAYQQAN +SKELNLDDTYTLSATDKVGGTGTIQGLPTGSLSYREILKRMMDESDNTAANIMIDKIGGI +STINAEIERLDLNDTQLERKMMDTD-ALADGKDNYTSVTDVATVLSKIYAGNLISQKADR +AMLTIMHQNAN-HAKLPHDLPSDATVYNKTGEYDYGVQNDAAIIKNNHGA-FVVVVLSQD +GNESEQ--V-------------- +>[subseq from] Beta-lactamase class A n=2 Tax=Chitinophaga eiseniae TaxID=634771 RepID=A0A1T4SUA7_9BACT +-kQLYDKLAPLLAAHHGQAGVYVHHLKTGRTV-AINADTVFPTASMIKMAIQVGVFHQLQ +EGTLQYRQLLTYRDSLLYPGEDILGAFRDSQITLDKVVMLMLTMSDNTASLWLQALAGGG +AQINTWLEGHGFVHTRVNSRTPGRAGDWKIYGWGQTTPREMGTLMEQIYKGEVVSHAASE +RMYRNLTRNFWDAEGL-RMVPPDVRTASKNGAVD-ASRSEVVLVNAPHGD-YVYCIITKN +NADRDNEAWELLRKVGSAIWQHy +>[subseq from] serine hydrolase n=1 Tax=Salinicola lusitanus TaxID=1949085 RepID=UPI000DA1EB17 +--------------GTGEIGVHVRRLDDGERV-GWRDAERWYWASLVKVPVAVELLDRIS +RDGADLDDTMTLHASDYVDGAGATNWAAPDTIPLRTLLERMLIDSDNTATDMLMRRV-GL +EAVNRRARSLTDEGIGPITTLIDVRRRYYATGLNSGRLDRYADMLERIDEGEALPAAATA +TLLSIMQRADTGHRRLAAGFQRQWPFAQKTGTQYS-RFCDAGILAPGTPGAVVIVSCLRD +AP-SRREAERTFQAIGRAV---- +>[subseq from] serine hydrolase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI001261B838 +------------------------------------------------------------ +---------------------------------------------------LVLEKIGGP +AALTAYLQSVGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ +QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITGLVWSAQQEPMFVSIYLTQ +TEATFDERNAAIVTIGKSIFDTf +>[subseq from] Beta-lactamase class A-like protein n=2 Tax=Bacillus TaxID=1386 RepID=A0A380X8D7_BACFI +--TLKAEILTLASCCEGRVAVYIHT-E-DGFI-EKDADAIFSSASLIKVPILLAGLLQAE +KGLLQLEEEVEVAASARVGGSGVLQAMARDLIKVTDLMTLMIIVSDNTATNLIIELL-GI +EKINQLFKDLGFNNTSLNRKMMDFE-ALKNGIDNTTTARDMVYGIKALAEQKLLSGKYTE +KALYILENQQFKNKLANTIDEEKVKVAGKTGELP-GIEHDCAIFTHKRK-TVCAAVLVDG +LQN-QAAGKEVLSAIGSRI---- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 187-3 TaxID=2486017 RepID=UPI000F73E2A2 +--KIKTDIQTTVGTISGLTSVYVAPTTGSQQV--VIDNQQQRAASSIKLFILAAAYSQVN +RGQLNLSELHTLSSAEIVGGTGLVQNAVGTQLSYQDLLTRMIQDSDNTATNIVIDKLGGL +NVVNQVAAQLGAKDTQLQRKMLDTQT-LAAGKDNLTTVQDIGNLLTKLYKHQLISKPADD +AMLGILATTKN-HSKLPQSLPAGTTVYNKTGEYDYGVQNDAAIIKNEKGA-FVVVVLAQN +GVES--QQVTAMNKLGALLY--- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7X1C4_9BACT +--HLRARVQDAEKRLDGVLGLSVKDLKTGTSF-EVRADEVFPQASSIKLAVLYELYRQAD +EGKIDLGQV-TRPPLPRVKGGGVLQELGDKVLTWRDLAVMMVGWSDNEATNVLISRL-GM +PAVNHRLEDLDLDHTRLRRKMMDLEAARRG-DENVGTPSEMRRLVEASYTGKGLSPAAAR +DIRAVLATPKD--SPFRVPLPETLVVMDKPGSLE-AVRCVTAVVDVPGR-PYAVSIETTF +LKKD-EDGAAAIREISAALYEMf +>[subseq from] serine hydrolase n=1 Tax=Paenisporosarcina quisquiliarum TaxID=365346 RepID=UPI000B89E8D1 +--KLVSRIEKLIVPSKGTWGIVLEDLNSGEKW-EHNEQELFYAASVIKLPIMASVYSAVE +RGDLALTDLIILDEQDYVGGSGVIQHFTPGSLPLKDIIMLMIIQSDNTATNLLIDLV-GV +ESIQNTMKEVGMVYSTFLNKLMLSKPNPK--GANCIAAVDISVLLHGMAIGGLVSNKASD +QMVDVMKKQQV-RDCLPEKLPAPWELANKTGWIP-GTRHDVGIFYVGDRE-FVATVLSKD +ED--DLISKRILSQIGEEIYNY- +>[subseq from] Beta-lactamase n=1 Tax=Saprospira grandis DSM 2844 TaxID=694433 RepID=J0P864_9BACT +-qALEDSLRAICQNPKGQMGIYVYDAQLDKSF-SIAGDTLFPLASVYKLPIVASLLAAQE +AGKLSLFDSIRLNLEDRRHSGCFMDWDTTGKPKIEDLALYMMRYSDNCATDALLRQLGGP +EFVQAQLKSWMVSDININRYLIEIFIKFLWDRRDQGSPKAFVHLLKGLDQEHWLNANSSQ +WLRDCLLSCRTGRYFLPKVLPPNRQVAHKTGSLP-GIYNDAGWIEREAGRPIYYAVFLKN +AFGKPKKERARIAAAMK------ +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga terrae Kim and Jung 2007 TaxID=408074 RepID=A0A1H4GEN8_9BACT +-kSLQQAISAAVAGFKGDVGVYVCQLSTGKYA-AINADTIFPTASIVKIPLLVGLFDKID +KGELQYHQTLWYRDSIRYGGSGIMQFFKDSTTELSVLAALMMAYSDNTSSLWNQSLAGGG +VTINKILEQYGLKDTRVNSRTPGREQDWKKYGWGQTTPREMASLLVKIRKQEVISPKASD +RMYRLMTKGYY-DEGAISQIPAWVQVADKTGSIDD-SKSEVLLVNAPHGD-YVLYIGTKN +IQADDNEAVVLIRRISAIVWKHf +>[subseq from] Beta-lactamase n=1 Tax=Acetonema longum DSM 6540 TaxID=1009370 RepID=F7NMC7_9FIRM +---------DRIQKEPGFYSLAVSLPDTQDRI-SINS-RRMSSASLIKIYIMTETLRQAK +EGILALDELLTVTAANRVGGAGELEFAAYGSYTILHLVEVMITESDNTATNLLIDRI-GM +DSVNRCMAGLNAADTELARRMMDFAAR-QEGRDNYTSVTDMVSVLERLYHRCCLDPFCDS +VMLAILKQQQD-RVKIPLYLPPGTVVAHKTGELDY-TEHDAGIVYGSKH-SYAVAIMAEQ +LM-DVAYGRHVIANMSKLIFEY- +>[subseq from] serine hydrolase n=1 Tax=Bacillus indicus TaxID=246786 RepID=UPI00068E2288 +-----KNAADILSSCPGRAGACFSW--NGEWL-EAGSSDVFSSASLIKLPILLTAFRLAE +KGNLDLNEKVKLRDVEKTGGAGVLQALSEDALSVQDLLTLMITVSDNAATNWVIEKI-GM +TKINETIEGLGLVDTKLNRKMMDLD-AIQSGMDNFTSPADMVRCLQAINEGDFVSEDSRQ +KMLAILQKQQF-TDKLPYNMDKDLIAGNKTGELP-GIEHDCAIIKYRDTT-VYAAVMIDQ +LEQ-KEWGRKTISEVGKLIYEK- +>[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3LDF9_9BURK +------------DANASAIAVAAYDFEHHTTW-SLNPARWFHAASTIKVPVLLGVYEAIE +QRRFEPYSRVHVRNRGVVDGRPFREVHAAIGLTVHELAEHMIVTSSNLATNVLLDLV-GV +EAARASLARLHLGGIDLQRGVEDE-VAWEAGINNRVTAAGLCDALRLIEEGKAISPEASK +AMLDILHQQRF-RSGIPAGLPEDARVAHKTGEIST-VAHDAGIVYLDGRDAYVVVILTEW +AP-DVSGRQETIARISRAVYG-- +>[subseq from] Serine hydrolase n=2 Tax=Luteimonas sp. 9C TaxID=2653148 RepID=A0A653V1K3_9GAMM +--DLDRRVRAIDARFAGELGVHVQRLDDDGAY-DFRGDEIWYLASGVKVPIAIAVLREIE +QGWLTLDTPITLLDTDFVDGAGRTNAHRAGDLAIGWLLEQMIIHSDNTASDVLIRTV-GL +GQVNAVASELIARDVRIT------------------------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=2 Tax=Luteimonas sp. 9C TaxID=2653148 RepID=A0A653V1K3_9GAMM +------------------------------------------------------------ +----------------------------------------------------------GQ +ARVRTLAQRLGV--TPADFLLPDLDSSYYATHVNSATLRDYGHMLAALQEGRALDLHRTR +YLLDVMARVQTGRQRLRAGLPPDARFAHKTGTQYR-RICDSGIASVPARQPHVVIAACAR +GAG-TVASERALRELGAAVT--- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A351C4E3_9BACT +--DMTGDIQTIIADYGATVAVSILDASKGFEL-HMDADRLFHAASTMKVPVLIELYRQAE +SGRFSLSDEVLLKNESIVDGSLFQYEQLGTPMALEQLAYNMITVSSNLATNLLIDFL-SA +DSVQTTSERLGTTHMQTIRGVEDLKA-FDLGMSNKATSRDLALLMELLRTGTAVSVESDA +AMREILNNQVF-QTMIPSGLPAGVRAAHKTGSIT-AIHHDAAIIYPPDSEPFVLVIMIQG +LQ-DHEASSLLGSEITRYVYK-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E7G417_9CHLR +--KLEDDLIDKLDQFPGVAGVSIKDLISGNDI-SINGNEIFPTASIIKIHILTYLLKMAE +SGSIDINKRISVDKNEFTGGTGILKYLKGKPLTLRDIAVLMIMLSDNTATNICIDLL-GI +ENINSFISDMELSSTKLNRKMMDEK-AIIQGNENLSTPKELTKMLEKLYLG-LPSKAVSK +DVLQIMSEPKN--SCLNLSTPSDITVANKGGGMEH-VRGDSGIVFLENN-PYIISILTKS +CYKGSGFQEKYIVNIAKDVFEIf +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5LBL3_9BACT +---LNEELETLSSESKARIAVALHDLESGLRF-SLHGDRWFHAASTIKVAVLLAIFRAAD +EDRLRLDDSLHVRNRFISAGSSFHYQAIGRTAKISALAEGMIASSSNLATNLLLDFL-GV +EYARNVLRDAHVEGVELRRGVEDH-AAHERGINNEATANGLLTLLSA-VRGNFLSSDSKE +QAIRILLQQRF-RSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EHDGRRETVAAISEAIFR-- +>[subseq from] serine hydrolase n=1 Tax=Chitinophaga polysaccharea TaxID=1293035 RepID=UPI001158CBF1 +-rKLEKGLRKIVAGFNGEVGIYVKNLRTGRYA-GINADTIFPTASIVKIPILVGIFDKIE +KGELKYHQPLIYRDSIKYGGSGLMQFFRDSTTELSVLLALMMSYSDNTASIWNQALAGGG +QRINELMERYGLAVTRVNSRTPGREGIWKVYGWGMTTPREMATLLVKIRNGEVVSKAASE +RMYRLMTHGYY-DETGLSRIPPYVQAAHKTGSLD-ASRSEVILVNAPRGE-YVFYVGTKN +NKTDDNEAQTLIRNISAYLWNYf +>[subseq from] serine hydrolase n=1 Tax=Nocardia flavorosea TaxID=53429 RepID=UPI0007A4FB00 +---VAERIHAVFADAGCTGRLHARRCDGGAAEvSIGGTERVVTASVYKLPLLLAYCRAVD +AGRIDPLERLTLIPAECTPPTGISALHDPVTMSRRDLATSMMTLSDNAAADLLLGEI-GL +AEVHDLLQSLGLLRTRLVGGTADIQRAYDPAYTSATTPEEMTRLLSALWRGEVVSAEQTA +FAQAVMRRQVW-PHRIAAGFPRGVSVAGKTGTIGI-IRNEIAVVEFPEEYPVAVAVFTRA +ARADVPAVDAAIAEAARIAVT-- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium scatologenes TaxID=1548 RepID=A0A0E3GQJ0_CLOSL +----EELLKNSLKNSESKYSLAVKNLKSKEIC-YMNVHEVVPSASIIKLFIMAEAFNENK +MGKLNLHDMIKIDNDKKVPFSIVSLLNSVEQYSIKDLITLMIIQSDNTAANVLIDFL-GI +DNINNFIKKTGFKNTILGRKMMDFEGD-KGGKDNYTSAYDIFLFLEKLYNNNLVGEKEDK +FMIDILSHQLD-FSMMRMDMLDDLKIAHKTGDLNC-LKHDVGIVYSEKVGDYIFVMFTYE +AK-SDGYARKLICKTSKQIYDYf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus invocatus TaxID=173959 RepID=A0A3M8BV51_9BACL +-eTLQGRLEQIIRNAQGTWGVVVEEIGEGICF-EHLPDKLFIAESVIKVPIMAAVFAQAH +QGAFSLDDRLPLRREDLVKGSGLLFALSPGLLSIRELVTLMIIQSDNTATNILIDLV-GK +ECVDQTMLELGMEQSKYVRKLMIYPAD--IDANNRITAGDVARMLNRLATGRFIHAHACE +DMVAIMKKQQF-RNGLPSMLPTDWEIASKSGWDT-GRQHDVGLLYTQGR-CFAITALSQD +VEAE--EALHT------------ +>[subseq from] Serine hydrolase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520H901_9BURK +--RLQAELSNIRADPHGAVGVHVRDLDTGLTV-SQHLDRPWYLASMVKVPVAIAVMRGID +AGHFRLDTPLTVRASDYVDGAGPTNKQPGKSLSVRFLLDQMIIQSDNMATDMLIGLV-GV +AEVNALVDTLVPDGFGRITTLGEVRRAYYASGLNTGRLEAYAALLALLADGKALSPKSTA +HLLKVMTRVATGTHRLKAGLPSDVGFAHKTGTQRR-RICDAGLIRAVDSERRVVVVACVR +DVLPLERAEAALMQVGAALCK-- +>[subseq from] SLH domain-containing protein n=1 Tax=Paenibacillus sp. XY044 TaxID=2026089 RepID=A0A259TBR0_9BACL +---------------GIRMTVGIRDLSGYETL-LLGSGEPYMPASTIKLAVVSALMQQVD +RGERSLTDQVTVTPEDVVGGSGSLQTNFPQNLTLERLARLMITQSDNTATNVLIDKV-GM +DRVQQLMDQLDLRTMHLGRKMFAAA--PSPAQDNFIDAADLTELLGQIYQGSFLSISSRN +QIIAWMARQEV-NTKFGAALP-DAPVAHKTGENAN-VTHDAGYFLVPGHE-LAVSVLLQV +TTEAQRIGNPIVQQVAKAVYG-- +>[subseq from] Beta-lactamase class A n=2 Tax=Maledivibacter halophilus TaxID=36842 RepID=A0A1T5M6Z3_9CLOT +---LRKTIDDLIKDAEGDVSVIIKNPKENESI-MINEDTVFPAASVIKLYILWELFERIE +KGEFTLEQEISIEDKDKVDGFGILKEHSGIKLSVKDLATLMIVLSDNTATNMLIDLL-GM +DNINRTIENNKLKHTVLQRKMMDGKAK-EKGLDNYTSSIDVLKILEKSLQK--------K +EIIDILKRQQC-NNKLPVLMGDSMELAHKTGDLP-GVEHDAGILFIKEEA-VFIIVLTKN +LK-NNIEGIKLNNNIGKAVYDYy +>[subseq from] Serine hydrolase n=1 Tax=Anaerolineae bacterium TaxID=2052143 RepID=A0A350WMD6_9CHLR +------NLESFIAQFEGTVSVSVQDLETGKGI-FINADVSMHPASTMKVPVMMEVFRQAE +AELLSLDESLKIFNSSIVDGSEFSYTRIGKSESIRELNRLMIVRSSNLATNLLMERV-TC +ASVDALIKELGIANMTVIRGLEDKK-AYRLNINNSASARSSTQMMKLIAEGKVVSRNVCD +EMIEVMFGQEF-NESIPALLPHNVKVAHKTGWTGD-FFHDTGIVFPPNRKPYAISLFTHG +FPDDENQAHECMAEVSRMIYS-- +>[subseq from] Beta-lactamase n=2 Tax=Oscillospiraceae TaxID=216572 RepID=A0A1C6H963_9FIRM +-------VKRQLSSVPGHIGFYYKNLVTGETD-GSRQTELFQAASVIKLPILAAILLEER +EHPGVLQERLLVRDGDKVPGCGALQHISGTQYDIESLCKLMITISDNTATNVLIRRF-GI +EFLNERFRVLGLQETKIFRFLFDTEAA-RQGKENLCQPKEIGSLLEEIYHGRCVSANASE +RMRAMLSQQQI-NHKIPSLLPPTVRVEHKTGEDE-GITNDVGILY--GREPCVLVLVSNE +TD--VPAFEQVIRTVS------- +>[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus sp. CF112 TaxID=1144311 RepID=J2QQD1_9BACL +--DLEKSLSAILQEAKGAWGVVVKELANGAYF-AHRPDELFIAESVIKVPIMAAVYAACE +QGKARIDAQLALRKEDLVGGSGFLYALSPGLLSIRDLVTLMIIQSDNTATNMLIDLV-GK +EQIDRTMRELGMERSRYSRKLMIYPQD--VTENNMITAGDVARMLEQIACGGLFSRWASA +DMIAIMQKQQV-LHGLPSQLPAAWELACKSGWDT-GRQHDVGILSVQGR-QFAIAALSQD +VRA--EAALHTLGLLGRAVYD-- +>[subseq from] serine hydrolase n=1 Tax=Candidatus Kryptonium thompsoni TaxID=1633631 RepID=UPI0007072E40 +--EIVSKINQIGKKYGGRLGVSAKNFVTGETI-QINADSLFPTASVIKVPILVELFYKFE +EGKLKKDTLISFDDSLKYGGSGVLQYFYDGALKLIDVAVLMIILSDNTATNLVLDCFADL +EAVNNRMKELGLNNTKILNKLMSFKTKKKTPEAGYTTPNDMVKLLELLANGKVINPEISA +EIINIMKNNQD-YEMMKRYLSENVTVANKSGSIDK-MKADIGIVYAKCV-TYAVAIFCDE +LSAVDNKGHLAVAEISKLIFDYf +>[subseq from] Serine hydrolase n=2 Tax=Bacillus TaxID=1386 RepID=A0A5D4SJH5_9BACI +-nQLEKRLADILRQCPGNASLAVEY--GERAI-HMNSGRKYPAASLIKIPIMMEAFFQAE +EGVLDLNEQVRIGGIEKAGGAGIIQSLSVTALSILDCITLMIIVSDNTAANLLIKLL-GK +KNINDRMHGLGLQTTVLGRKMMDFEAA-AKGIDNFTTAADMVKCLRAIKDGELFSEKNRS +KMLDIMEAQQF-REKLPALACKELKIANKTGELP-GIEHDCAIFAS-GRDVLYAAVLIEG +LS-SPEEGNHAIRLIG------- +>[subseq from] Beta-lactamase n=2 Tax=Cyclobacterium qasimii TaxID=1350429 RepID=S7WVD1_9BACT +-nQLENGIRDLMQGVEGDFGLAFRLLDSGKEL-FINEKEVFHAASTMKTPVMIELFKQSA +AGKFSLQDSILIRNESILDGSAYSYSRIGEKGSRYELMYQMIIKSSNLATNILIEEV-GA +ENVTQTMRDLGALDIQVLRGVEDLKA-FEAGLSNTTTALDMMLIMEAIAKGKVVGS---G +NMMEILSDQHF-NGLIPKYLPKTAKIAHKTGSIT-GVQHDAAIVDLVNGKRYVLVILSKN +LK-DEEVGKESIAKISQLIYTY- +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus indicus TaxID=223556 RepID=A0A2D0A750_9DEIO +-------------GFAGTVGLWVGTPDGEALA-SLNGDRVFPAASTIKVPLLVMALQDAQ +RGDLRLEDRVVLQAADRVPGAGVLHELGAGLLSWQDVLTLMIIVSDNTATNLTIGRL-GV +EAVNRWLGAHGLSGTRLVGKLQQRNEAQRRGERNATTAADQARLLRLLLAGDLLDPPHTA +LAVSILERQQY-RDLIGRGVPADYRVASKSGELT-GVHHDVGVIFTP--RPLVVALLSEG +GRREHPENRDVTALAA------- +>[subseq from] Beta-lactamase n=1 Tax=Saprospira grandis (strain Lewin) TaxID=984262 RepID=H6L7V4_SAPGL +-eALKDSLRTICQNPKGQMGIYVYDAQLDKSF-SIAGDTLFPLASVYKLPIVASLLAAQE +AGKLSLFDSIRLNLEDRRHSGCFMDWDTTGKPKIEDLALYMMRYSDNCATDALLRQLGGP +EFVQAQLKSWMVSDININRYLIEIFIKFLWDRRDQGSPKAFVQLLKGLDQEHWLNANSSQ +WLRDCLLSCRTGRYFLPEVLPPNRQVAHKTGSLP-GIYNDAGWIEREAGRPIYYAVFLKN +AFDKPKKERARIAAAMK------ +>[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea maritima TaxID=683260 RepID=A0A1G9AKY9_9ACTN +------DFERIFRQAGVTGWLHATDIDAGREV-GHGADEPLPTASMFKVPLLVALCRQAD +AGLLDLSCRVTVTDADRAPGSTGLSAMRDDVISLRDLAYSMISVSDNTSADQLLSRV-GY +AAIGAVLESFGLAVTRVVQSAGEMLAALDPARANRSTPREMTTLFGLIWRDEAASAESCA +WMRTLFNAQVW-PHRLASGFPDDVSVSGKTGTLPT-LRCESGVVEYPDGGRYAVSVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5K945_9BACT +--TLRNELEKIAGESKANISVAVLDLESGFRF-SLAGDRWFHAASTIKVAVLLAIFRAAD +EGRLRLDDPLHVRNRFLSAASPFRYRAIGRTVKILALAEGMIAASSNLATNLLLDFV-GV +EYARDVLRDAQISGVELRRGVQDENA-HEKGIDNEVTADGLLTLLCA-VRGDFLKQQSRE +EIIRILLAQRF-NSMIPAGLPPHATVAHKTGEIST-ACHDAGIVYLPEREPYIVVILTEF +DA-EKDGRYQTLVGISNLIYR-- +>[subseq from] serine hydrolase n=1 Tax=Selenomonas sp. ND2010 TaxID=1410618 RepID=UPI0009DDA998 +--QLESSLRELMDKDSAKYQVYVFLPQWDEPL--IMGEEPQSSASIIKIFILGTAYELAE +RGQLNLNQQVTVHQADMVGGAGVINGRSGEPYTVRNLLELMITESDNTATNVLMDTI-GI +ERIQRFMKVHGFQNSVLQRKMMDFE-ALRAGRDNFTTAGDVGKFFRLLREHKLVSEAADS +EMISILFGQTD-RECFPQALP-DARIAHKTGELS-GVYHDAGIVYEAND-SYVLCIMSTD +SRGR-GNTLSTMRDMAKTV---- +>[subseq from] Beta-lactamase n=1 Tax=Flavisolibacter tropicus TaxID=1492898 RepID=A0A172TXN2_9BACT +-kKLQQQLEVLVKDFKGDIGVYVKDLHSNKVV-NINADTVFPTASMVKVPILVGVMDKIN +RGELQYHQPLTYRDSLLYEGEDILGSFKQDEIQLSKVMMLMLTTSDNTASLWLQSLAGKG +TRINEILDSMGFVNTRVNSRTPGREANRSQYGWGQSSPKEMASLFEKIYKGEVISNAASD +KMLRLLNRNYY-DEVAISQLPPNALVYSKNGAVNQ-TRNETLLVKG-NKAEYVFCIMSKN +NQNNENEAWVLTRKISQLLWNYy +>[subseq from] Serine hydrolase n=1 Tax=Microbispora triticiradicis TaxID=2200763 RepID=A0A372PGJ2_9ACTN +-------LERVFRNAGVTGWLHAVDVDGGREV-GLRAAEPVVLASVFKLPLLLELHRQAE +RGLLDLAGLVRVPAEGRTRGTGLAAMLDDATLSLRDLAYLMMTVSDNAAADVLLARV-GR +EAVNTLLDGLGLTETRVVHDCRDMLTALRPERSNRSTPREMTRLLAMIWRDEAAGAASCA +AVRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +LSQNQPRADAAIGAAARIAIDQ- +>[subseq from] Serine hydrolase n=2 Tax=Microbispora TaxID=2005 RepID=A0A5D0P3J4_9ACTN +-------LERVFRNAGVTGWLHAVDVDGGREV-GLRAAEPVVLASVFKLPLLLELHRQAE +RGLLDLAGLVRVPAEGRTRGTGLAAMLDDATLSLRDLAYLMMTVSDNAAADVLLARV-GR +EAVNTLLDGLGLTETRVVHDCRDMLTALHPERSNRSTPREMTRLLAMIWRDEAAGAASCA +AVRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +LSQNQPRADAAIGAAARIAIDQ- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium mizutaii TaxID=1010 RepID=A0A239XUU8_9SPHI +-kKLTEKINQAIAGFQGDIGIYVKHLKHNKIV-NINADSTFPTASVVKVPILVGVFQKIN +DGELRLDQEFLYRDSRAYGGSGLMQFFKDSTTDLATLIGLMLSYSDNVTSIWCQELAGGG +QSINPILDQLGLPNTKVNSRTPGREEIWKKYGWGQTTPREMATLYEMIRNGKVVSPAHSD +KMYRFLKNQFY-NERALSQFPAQVSWIGKTGSLDE-VRSEVVLVNAPHGD-FVFSFFSNN +NKTKSNEAEVLTRKIANIIWNHy +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga sancti TaxID=1004 RepID=A0A1K1SWV4_9BACT +-qKLEKGLHDVISGFRGDVGIYVRNLKTGHYA-EINADSIFPTASIVKVPILVGVFDKIE +KGELQYHQPLVYRDSARYGGSGIMQYFKDSATELSVLLALMMSYSDNTASLWNQALAGGG +ERINQLMEQYGMQVTRVNSRTAGRQEIWKIYGWGMTTPREMATLMLKIRNGEVVSKAASE +RMYRLMTHPYY-DEGAISAIPPYVQAAHKSGAID-ASRSEVVYVNAPHGE-YVFYVGTKN +IVTDDNEASTLIIKVSKYLWEYf +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00138E2928 +------------------------------------------------------------ +------------------------------------LIEAPMKYSDNTANNKIINEIGGI +KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK +DNKSDKPNDKLISETAKNVINKf +>[subseq from] serine hydrolase n=1 Tax=Halotalea alkalilenta TaxID=376489 RepID=UPI000694F2BD +---LAPLVAQIDQEFPGELGFYLRDLDSGEYF-SLRAQEQWYLASMVKLPVALALLDMVD +RSEASLDERMTLNASDYVDGAGETNWHGPGALRLGWLLEQMIIRSDNTATDMLIRRI-GI +ERVNARRAELVAHGFGEITTLADVRRAYYATGANSGRLDAHALLLERLQRSDALSTPSTV +HLLGVMSRVVTGEHRLKAGWPDSVGFAHKTGTQR-GRFCDGGIASRTVGTRRLVVVACTR +GSLSLADAERAMRELGAAAWR-- +>[subseq from] Uncharacterized protein n=1 Tax=Anaerosporomusa subterranea TaxID=1794912 RepID=A0A154BW80_ANASB +---LRQQIEQHLAGTPGTYSIELVLPDLGMGL-RYNP-IVLPSASLIKVFIMAEAFRRAS +IGCLDLSDSAEVTPAVRVGGAGPLEHAAYGTIKLLELIELMITESDNTATNILIRIL-GM +DSVNKLAYTIGCHNTLLGRHMMDFTAR-AAGRDNLTSPTDMNILLGRLYTNGCINPASSQ +AMLAILLRQTD-KCKLPLLLPPGTVIAHKTGELD-GIEHDSGIIYG--QTPYILTIMTEN +LPV-EEQGRQTIAELSRIVYDA- +>[subseq from] serine hydrolase n=1 Tax=Anaerocolumna aminovalerica TaxID=1527 RepID=UPI000BE25213 +-----------LQKITGKAGFYYKNLVTGEQI-TFQEDMPFQAASVIKIPILIEAFTRLE +TGSLHKTDLFTIKKQDKLPCGALTYMHDGLQVTLEDLYTLMIILSDNTATNLLIEHL-GM +DQINNTMQKLGCRQIKLNRYLFDSEKA-ALGIENYISAGDIAGLLEKMYHGELVSKEASA +EMLRILKNQRL-NGKIPFFIHGKADIAHKTGEDD-GITHDVGIVYG--KEPFIICFCGNE +--VDVPAYERLMQDISYALFK-- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7QXL7_9BACT +----RAALEARIARAPARVGLYYRSLARADSI-LIGANLRFHAASTMKLPVMIQIFRDAD +TGLLGLDDSLTVHTASLVEGAFVVYALVGRNRAVRDLLERMITRSSNLATNILIERV-GA +ARAQASARSLGAWSIQVLRGVEDGA-AYRAGLNNTTTARDLGVLLQAIATRRAASGAACD +SMLAILGRQEF-NEGIPVGLPPGTRVAHKTGWVGEVVYHDAAVVFPPDGGGYVLVVLTGG +IKED-SVAHNLVADLSRLVHD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus firmus DS1 TaxID=1307436 RepID=W7L1U8_BACFI +-hTLKAEILTLASCCKGRVAVYIHT--EDGSI-EKDADAVFSSASLIKVPILLAGLLQAE +KELLQLEEEVEVTASARVGGSGVLQAMARDLIKVTDLMTLMIIVSDNTATNLIIELI-GI +EKINQLFKDLGFNNTSLSRKMMDFE-ALKSGIDNTTTARDMAYGIKALAEQKLLSGKYTE +KALYILENQQFKNKLANTIDEEKVMVAGKTGELP-GIEHDCALFTHKGK-TVCAAVLVDR +LQ-DPAAGKEVMSAIGSRI---- +>[subseq from] Serine hydrolase n=1 Tax=Runella sp. YX9 TaxID=2282308 RepID=A0A369ILF3_9BACT +---------------------------TGEIYfSKGPAESVPSASIIKIPILVELMEQVK +AGKVDLDETYTLVTADKTGGSGVMASYPDGQMSLKEVARLMMIASDNTATNIFIRKL-GR +EKINDRMKFFGLASLQLNRVMMDTAA-VARGIDNYVTARDINALLRLIYGHKVATPALCE +QMMEFLFENRD-TVTLPRLIPKTIKIAHKTGGLTY-VRGDAGIVFAA--TPFVISVFVRG +TPE--KDAEKMIGEIGEICFNIf +>[subseq from] Serine hydrolase n=1 Tax=Rhodohalobacter barkolensis TaxID=2053187 RepID=A0A2N0VEX5_9BACT +-dQLKADIENHISEEEGTFAIWFQHLQEPDRFfAINEDTLFHAASTMKTPVMIELFRRAE +AGEFDLSDSIEIENKSIVDGSEFQERRVGEMATLYDLNHAMITYSSNLTTNLLIRLV-GA +EETTETMRDLGAESIQVLRGVEDLKA-FDQGLSNRTTAKDLGIIYEHIANGTAVSPEMDS +VMVEVLKDQYY-QDVLPEYLPDDVVAANKTGFIT-GVRHDSGIFYLPDGQSYILIFLSKN +LP-DEDRGRDVGREISKKIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Salinicola sp. TaxID=1978524 RepID=A0A2D8NXX2_9GAMM +-------------TVAGEIGVHVRRLDDGERV-GWRDAERWYWASLVKVPVAVELLDRIS +SDGVDLDDTMTLHASDYVDGAGATNWAAPDTIPLRTLLERMLIDSDNTATDMLMRRV-GV +EAVNRRARSLMDEGIGPITTLIDVRRRYYATGLNSGRLDRYADMLERIDKGEALPAAATA +TLLSIMQRADTGHRRLSAGFQRQWPFAQKTGTQY-ARFCDAGILDPGTPGAVVVVSCLRG +A-PSRREAERTFQAIGRAV---- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus aquatilis TaxID=519440 RepID=UPI00037A0CB9 +-----------ERGFAGVLGVRVCDEAGQELF-SLKADRVFPAASTIKIPLLVMALQAAQ +RGELILTDRVTMHAADRVPGAGVLHELSADLLTWQDVLTLMIVVSDNTATNLVIDRL-GV +QAVNAWLDTAGFASTRLVGKLAQRNEAQRRGERNRTTAHDQTELLGRLWRGDFLDSTHTD +LALSILSRQQY-RDLIGRRVPCGYRVASKSGELG-GVHHDVGVLWTP--RPLVVALLSEG +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Olivibacter sp. LS-1 TaxID=2592345 RepID=A0A5C0ZPR3_9SPHI +----KRKIEKVQKGNPGTFAIAFKDLSDNDTF-FYNEHQLFHAASTMKTPVLAETFRQIE +RGKLALSDSVEVYNESIYDGSSYAYSLIGKKAALADLLLRMITQSSNLATNIVIDLV-GA +KNVMKTMERLGAKEMKILRGVEDSKA-FAHGMNNMVSAYDLSLLFVQLARGEMINSRSSE +QMLDILMKQHF-RGIIPAELPADVKVANKTGSINK-VCHDSGIVFLPDGRKYVLILLSMG +VD--EKLAQQYLAEISGVFYHY- +>[subseq from] serine hydrolase n=1 Tax=Olivibacter jilunii TaxID=985016 RepID=UPI001031BE8E +----KRKIEKVQKGNPGTFAIAFKDLSDNDTF-FYNEHQLFHAASTMKTPVLAETFRQIE +RGKLALSDSVEVYNESIYDGSSYAYSLIGKKAALADLLLRMITQSSNLATNIVIDLV-GA +KNVMKTMERLGAKEMKILRGVEDSKA-FAHGMNNMVSAYDLSLLFVQLARGEMINSRSSE +QMLDILMKQHF-RGIIPAELPADVKVANKTGSINK-VCHDSGIVFLPDGRKYVLILLSMG +VD--EKLAQQYLAEISGVFYHY- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7G2L9_9BACT +---VRERLAARVAQAPATVGLYYRSLTHPDSL-LLDANVRFHAASTMKLPVLIQVFRDAD +AGLLRLDDSLTVHVVSLVDASPFDYGRVGRPASVRDLLELMITRSSNLATNILIERV-GA +GRAQGSARALGAWSIQVLRGVEDGK-AYRAGLNNTTTARDLGVLLAAIAQNRAASPASCR +EMLRILEAQEF-NEGIPVGLPPGTRVAHKTGWIGEVVYHDAAVVYRSSGGSYVLVVLTGG +IKQD-SVAHNLVADLSRLVY--- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7ERK8_9BACT +-----ERVAARVAQAPATVGLYYRSLTRPDSL-LLGANLRFHAASTMKLPVMIQIFRDAD +AGLLGLDDSLPVHATSLADGSPFDYRRAGKLASVRELLELMITRSSNLATNILIERV-GA +ARAQASARTLGAWSIQVLRGVEDGK-AYRARLNNTTTARDLGVLLAAIAGRRAASPAACD +SMLAILGRQEF-NEGIPAGVPSGTRVAHKTGWIGEVVYHDAAIVHPATGGSYVLVVLTGG +IKQD-SVAYNLVADLSRMVYA-- +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus ficus TaxID=317577 RepID=A0A221SY04_9DEIO +------------SGFAGEVALHVTDLGGRVLC-SHQPDEAFPAASTIKVPLLVQALQEAQ +AGRLDLTGRVTLGAADRVPGSGVLHDLLPGLLAWQDVLTLMIVVSDNTATNLVIGRL-GV +DAVNAWLAAQGLSGTRLVGKLEQQNEAQRRGARNRTTARDQAALLGALVRGELLDPAHTR +LALDILERQQL-RDLIGRRVPADYRLGSKSGELR-GVHHDVGILHTP--RPLVVACLSRG +GTDPRE----------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Dolichospermum circinale AWQC310F TaxID=553470 RepID=D1FNP1_9CYAN +---------------------------------------------------------DVD +AGKIRLDEILTLEKEMIVGGSGNIQQAPGSKYTALDLATKMITISDNTATNMLIAKLGGQ +EALNGRFRSWGLTTTMIRSPLPDLQGT------NTTSPRELGNLISMVNQGNVVTMRSRD +SMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVQR +PNND-PRAAKLISSISSSAYQYf +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_40CM_68_21 TaxID=1805084 RepID=A0A1Q7EWR3_9CHLR +------------ASFPGEAAAFACDDRGGELF-AERADEVFPAASVIKLPLVMALYADAA +RGEIDLGERVRVG--DRVDGTGVLRHMRDVEASLRDLAMLSIIVSDNTATNLLVDRF-GL +ERVNERMREWGCSESRFARKMYDFDAA-KCGKENFMTARETASLLLRLLRGGCGDRATSD +AVLAILDECQD-RTMLRRYLPYGAKVAHKTGTLDE-SRNDAAIVRG--ERPVVVAAFSRK +VS--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Thermoflavimicrobium sp. FBKL4.011 TaxID=2137476 RepID=A0A364K797_9BACL +---LETQIKKYVDSFDGKVGVAIQ-TEAG-SI-HYREHEPFLAASLIKIPIMIEAYRQVQ +AGRLDLYQLYKVPSNQRVGGSGVLFNLGEEIVSLQDLISLMIMISDNTATNFIIDQI-GI +DTVNDLASELKCDQTMLGRKLMDYTA-KKRGFENFTSAYDMVHFFKEMVEGNSLHPEYKR +LILKSLRAQQF-QSKLPGDLGEGDFIAHKTGEMTN-YEHDAGILSVGGK-VAYIAVLTSD +GP-DAFTRRTLIADIGKAVFD-- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium carboxidivorans P7 TaxID=536227 RepID=C6PSK5_9CLOT +---LEELLKNSLKNSEAKYSLAVKNLRSKENC-YINTHEVVPSASIIKLFIMSEAFNKNK +MGKLNLHEIIKIDNDKKVPFSIVSLLNSVEQYSVKDLITLMIIQSDNTATNVLIDFL-GI +DNINNFIKERGFKNTVLGRKMMDFEGA-KAGKDNYTSAYDVFSFLEKLYNHNLVGEEEDK +LMIDILSHQLD-FSMMRMDMLDDLKIAHKTGDLNC-LKHDAGIVYSEKVGDYIFVMFTYE +AK-SDGYARKLICKTSEQIYDYf +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6C9C6P9_ECOLX +------------------------------------------------------------ +------------------------------------------------------------ +-----FLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas indica TaxID=137658 RepID=A0A1G9IQF2_9PSED +--QLQGKILRLDQRTPGDLGVYIKHLGDGGEL-DYQAGRHWYLASAVKVPVAIATLQRVD +EGVWPLDQRLALRNEDKVDGSGGLAQDSGSEYDLKTLLEEMLQRSDSTAADMLINRV-GE +DELNRRIASMADQGTSLLRVRHELYRRYYARRLNAATLRAYGGMLEKLARGRLLSRANTD +LLLDLMGLDEYHAYRLEAGLGKDVPFAQKTGTQFE-RACHMGIIDPKSEQAIVIAACVED +AGQE--QAAQTLEM--------- +>[subseq from] Beta-lactamase class A n=1 Tax=Natronincola peptidivorans TaxID=426128 RepID=A0A1I0FZL7_9CLOT +--RLQERIQQHIDKINGTVGIYIKNLNNNKTI-IINGDERFHSASIIKIPILWEGLRQVE +IGMKTLEETIALKKEDKVGGCGVLTLLQEGLLTLEDLLHLMVDISDNTATNMLIDHL-GR +DNINATLQSMGMKNTYLARKLMMVIPE----TYNYTTPKDIGSMLERFVIGNGLNNVYAE +KGMEILSKQQL-ND---------------------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Salinicola acroporae TaxID=1541440 RepID=UPI0013A65FF4 +---------------TGEIGVHVRRLDDGERV-GWRDAERWYWASLVKVPVAVELLNRIS +RDGADLDDTMTLHASDYVDGAGATNWAAPGTISLRTLLERMLIDSDNTATDMLMRRV-GL +EAVNRRARSLMDEGIGPITTLIDVRRRYYATGLNSGRLDRYADMLERIGKGEALPAAATA +TLLSIMQRADTGHRRLSAGFQRQWPFAQKTGTQY-ARFCDAGILAPGTPGAVVVVSCLRG +A-PSRREADRTFQAIGRAV---- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7U8L5_9BACT +---------AIRDRHEERLGIAFYDAETTLQW-SYNADAMFHAASTMKLAVLLAVFRQHT +RGELALEEPVHVRNKFLSIRKPYMFERLGRTMSVEQLAYHMITSSSNFATNLLVDVV-GV +PVIQTALDELKIEGIKVLRGVEDQ-AAFEAGLNNEVTANGLLKLLRLVEEGKAYGEEASA +RMREILLDQRF-KSGIPAGLPQAARVAHKSGNIST-VHHDAGIVYLEGRKPYVLVILTQF +PSE--TGARTAVADVSRDIYE-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3D1V647_9CHLR +----------------------------GNRW-SHNGQRQFKAASTVKIPLMIEIYRQID +RGERSLDERHVLSAIEKAAGSGVLLHHDGIELTLDDLIYLMISISDNTATNMLIDLA-GM +DAVNATMLELGMSMSTLARKMKGRP-AIEGEQENLATPDDYVAIVDAIFGDRATSTAARE +AMVTMLSRQQN-ARRIARYLPADLRWGSKTGSIA-GVTNDVGFVETPVGR-MILAVFCEG +FP-DQHDGEYAIGELSRAALH-- +>[subseq from] Uncharacterized protein n=1 Tax=Prevotella sp. P3-122 TaxID=2024223 RepID=A0A255T0W8_9BACT +----------------------------GDLYcGHQEDSAFAMHSVMKFPQALYVADYLH +KKGLTLSDSVLVHKDSLDAWSPMLSIFEGMRFTFAELIEWSLKQSDNNACDLLFASCGQP +DAVEKYIHTLGFKDIHVRLTEKEMKKNPHRATGNSATPKEMARLLEWFYLHRN-DNKNLS +FIWNTMADCNTGKQRIAAVLPKGGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFLQN +SKEEKEVAE-------------- +>[subseq from] serine hydrolase n=1 Tax=Pseudomonas indica TaxID=137658 RepID=UPI000BAB35AB +------------------------------------------------------------ +----------------------------------------------------------GR +ERVRALARTLDVDPSELRSLEQAYQ-RYYARRLNAATLRAYGGMLEKLARGRLLSRANTD +LLLDLMGLDEYHAYRLEAGLGKDVPFAQKTGTQFE-RACHIGIIDPKSEQAIVIAACVED +AGQE--QAAQTLEM--------- +>[subseq from] Serine hydrolase n=1 Tax=SAR202 cluster bacterium TaxID=2030829 RepID=A0A5N9FY17_9CHLR +-eQLENTLKDKITSFDGVAGLAVKSLTGGKNI-SINGDEVFPTASTIKIHVLAKLFSLQE +EGEIDLSARIRFTRNMYGAGSGVIHFLENDPFTVLDVAILMMLASDNTATNTCIDIA-GM +EGVNDLIRDMGLSKTKLRRKMMDPE-AINRGDENVSTPNELITMMDHLHNQKP-SPKVSA +QVLRIMSKPKS--AYLNKAIGSTVVVANKPGGMDK-VRGDTGIVYLPNN-PYAVSIMSKF +SMVDSIAQEGFLIDLARTIH--- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_1_20CM_3_53_8 TaxID=1803431 RepID=A0A1Q7YCY4_9BACT +---LDARVRAEISSFKGHVHLFAKNLDSGETY-ELNADDVVPTASTIKVAIMVEAFARVS +EGRSKWMDEILLTPQAKKVGSGVLQNLSDNLLTLRDVVTLMIIVSDNAAANLVLDVV-TP +DAVNARMDSLGLKQTRVLRKIGAGNTFITRYGTGMTTPREMLELLEMIERGQIINAAASR +EMIDIMKRQQL-HYGIGRNLQ-GIEIASKSGALDH-LRSDVGIIYTRRG-RIAMAVTCND +IPSYDNPGDLLIARLSQILID-- +>[subseq from] serine hydrolase n=1 Tax=Luteimonas abyssi TaxID=1247514 RepID=UPI0009E8E54B +------------------------------------------------------------ +----------------------------------------------------------GE +PRLVALAERLGVSRTDLDANLDEVFARYYDTGRNAATLEAFAVLLERLVTGDLLSPESTA +IVLGHMRSISTGDRRIQAGLPRGADFAQKTGTQF-ARACNVGVIDADRGDGAVIVAACAE +DYDDIAEAEQAFEALGRAL---- +>[subseq from] serine hydrolase n=1 Tax=Gelidibacter japonicus TaxID=1962232 RepID=UPI0013D74D9C +-kTLEKGLQDLAKDFEGDVGIYVYNLKTNQEA-GVNADTIFPTASVVKVPILIEVFKQIK +AGKLHLKDTLVYDAKRKYGGSGLMQFYKDSTTDLRTLASLMITMSDNTTSLWCQELVGGG +EAINETMADLGLAHTRVNSRTEGRTKDWEAYGWGQTTPREMASLLIKMRNRTLVDAASSD +EMYRIMSNSFYTDYSL-SQIPPYVQTAAKQGMVNK-SRSEVVMVNAPSGD-YVFYIATKN +NTDEDNKAWQLQRLISAY----- +>[subseq from] Beta-lactamase class A n=2 Tax=Sphingobacterium nematocida TaxID=1513896 RepID=A0A1T5F351_9SPHI +-rALEHKIKKEINGFQGDVGIYVHQLKTNKIV-SINADTVFPTASIVKVPILVGVFQKIA +QGELKLNQAFKYSDKRAYGGSGLMQFYKDSATDLSTMISLMLTYSDNVTSIWLQELSGGG +AMINPLMDQLGLEQTKVNSRTPGREKIWEEYGWGQTTPREMAKLFTLIRNGQVVDARHSD +KMYRYLKNQFY-NGRSLSQLPPEVNAIAKTGSVDQ-ARGEVILVNAPSGD-YVFCILTKN +NKTDDNEAEELTRKLSSIIWNHf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2W0BIW7_9BACT +-sALQSKIEALAAQHHGKLTLYASNLKTGATV-AVDAEKAVPTASVIKLPILVDAMEQVK +AGKHKLSENITLQKDDIVQGSGILQFFDTPLITLKDALTFMIVESDNTATNLVIDQI-GI +KNVNDHIASMGLKDTYLYKKVFKMPAEQKKFGLGKTSAMEMAKVMESIVRCDLKDQVLCD +DMLYMLRNQQY-RNLVPHYIETSSLIANKTGSLDE-VRNDVAVVYSKNG-PIVISAFTYD +NQNNDNAAELLVAHVAKLIMEAw +>[subseq from] serine hydrolase n=1 Tax=Sphingobacterium sp. 1.A.5 TaxID=2044604 RepID=UPI000C0C0497 +-kSLERKINQAIEGFQGDIGVYVKHLKKNKEV-AIHADSIFPTASIVKVPLLVGVFQKIK +NGELRLDQKFLYRDSRAYGGSGLMQFFKDSTTDLATLIGLMLSYSDNVTSIWCQELAGGG +QTINPILDELGLKNTKVNSRTPGREEIWKKYGWGQTTPREMSKLFELIREGKVVSPEHSD +KMYRFLKNQFY-NERSLSQFPAIINTISKTGSLDD-ARGEIVLVNAPHGD-FVFTILTKN +NKTKENEAENLTRKIANIIWNHy +>[subseq from] serine hydrolase n=1 Tax=Rubrivirga sp. SAORIC476 TaxID=1961794 RepID=UPI000BA919BF +---LAETVDAIVAQYGATVAVAVRS--PSRRF-DRLADRTFHAASTMKVGVMIEAFRQVQ +AGRRAWDDPVRVENRSIVDGTEYQYALQGRDVTFRTLTERAITTSSNLATNLLIGLV-TA +ESVQATMDRLGAPGLRVLRGVEDLKA-FEAGLSNATTADALATVLEAIRDGRAVSPAADA +EMVDILDDQAF-NEMIPAGLPAGTRVAHKTGWITE-IHHDAAIVYPEGAEPYVLVILTEG +LA-DHDESARLGAEVARAVH--- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536Q7A3_9CHLR +--------------FPGEAAAFACD-DRGRELlAEQADELFPSASVIKLPLVMALYADAA +RGEIDLEERVRVGE--RVDGSGVLRHMRDVELSLRDLAMLSIIVSDNTATNLLVDRF-GL +DRVNERMREWGCSESRFARKMYDFDAA-RCGKENLMTARETASLLLRLLRGDCGDRATSD +AVLAILGECQD-RTMLRRYLPYGAKLAHKTGTLDE-SRNDAAIVRG--ERPVVVAAFSRK +LTDT------------------- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus ficus TaxID=317577 RepID=UPI0006864017 +------------SGFAGEVALHVTDIRGRVLC-SHQPDEVFPAASTIKVPLLVQALQEAQ +AGRLDLTGRVTLGAADRVPGSGVLHDLLPGLLAWQDVLTLMIVVSDNTATNLVIGRL-GV +DAVNAWLAAQGLSGTRLVGKLEQQNEAQRRGERNRTTARDQAALLGALVRGELLDPAHTR +LALDILERQQL-RDLIGRRVPADYRLGSKSGELR-GVHHDVGILHTP--RPLVVACLSRG +GTDPRE----------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1G7RKJ5_SELRU +--QLEASLRQLMDKDSAKYQVYVFFPQWDEPL--VMGDGPQSSASIIKIFILGTAYELAE +RGQLELNQQVTVHQSDMVGGAGVINGRSGEPYTVRKLLELMITESDNTATNVLMDTI-GI +ERIHRFMREHGFQDSVLQRKMMDFE-ALRAGRDNFTTAADVGKFFRVLREHKLVSETADS +EMIAILFGQTD-TECFPQALP-QARIAHKTGELS-GVYHDAGIVYEAND-SYVLCILSTD +SRGR------------------- +>[subseq from] Serine hydrolase n=1 Tax=Streptosporangium minutum TaxID=569862 RepID=A0A243RL42_9ACTN +-----------FRAAGVTGFLHAVDLDTGAEV-AHDADEPVVMASVFKLALLVEFFRQAD +AGLLDVTERVTVMADRHTPPTGVSAMADDVTMSLRDLAYLMIAVSDNTAADTLAGRV-GL +SAVNTMLAAEGLDGTWVEHDCRGLFAALDPARTSRSTPRDMTRLLGMVWRDEAASAASCA +SMRRLLGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRS +TAQNQPRADAVIGTAARAAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3D1TZC7_9CHLR +-----------------------------------NADELYLLASVFKVPILLEALAQVD +EGRQGLDERFELRRDDQLPTSIILEHLDPGLLTLRDLLTAMITVSDNTATDMVLAIV-GL +ENVMARLTSWGLRDIAIHMSVQGLFDAQRTLENNVSSPRAIGELLERLVRGELLSRESTG +VALDIMLRQQL-NQRLPRFLPANVPIAHKTGIFYS-SRNDAGILYLPDGGRVVVVSFS-- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6KPE4_9BACT +----------------------------DRIL-LRNADRIFPTASSIKIAILLELYRQDQ +KERAKLDDLYTFDPKDLVEDSRIMAGLTPGVVTNRDLAQFMIAVSDNAATNILIDRV-GK +DNVNTMLRGLGFSKTLLRRKMMDTAAARRG-DENVATPQEMARLLEAIYKEMVLNKQATA +ELIKQLSTKKE--SYIPRYLSENIQVANKPGELE-GVRNDCGIVFVQNR-PFIVSVMTAY +DR-DEKAAERAISDVALHAYYYf +>[subseq from] serine hydrolase n=1 Tax=Streptosporangium minutum TaxID=569862 RepID=UPI0013FD10BE +-----------FRAAGVTGFLHAVDLDTGAEV-AHDADEPVVMASVFKLALLVEFFRQAD +AGLLDVTERVTVMADRHTPPTGVSAMADDVTMSLRDLAYLMIAVSDNTAADTLAGRV-GL +SAVNTMLAAEGLDGTWVEHDCRGLFAALDPARTSRSTPRDMTRLLGMVWRDEAASAASCA +SMRRLLGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRS +TAQNQPRADAVIGTAARAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia speluncae TaxID=419477 RepID=UPI00082B25FC +----AERIHAVFADAGCTGRLHARRCDGGAEV-SIGGTERVVTASVYKLPLLLAYCRAVD +AGRIDPLERLTLTPAECTPPTGISALHDPVTLSRRDLATSMMTVSDNAAADLLLGEI-GL +PRVHDLLDSLGLTRTRLVGGTADIQRAYDPAYTSATTPEEMTRLLSALWRGEVVSPQQTD +FARAVMRRQVW-PHRIAAGFPRAVSVAGKTGTIGI-IRNEVAVVEFPGEYSVAVAVFTRA +ARADLPAVDAAIAEAARIAVT-- +>[subseq from] Uncharacterized protein n=1 Tax=Aneurinibacillus sp. XH2 TaxID=1450761 RepID=A0A109QEB4_9BACL +-------------QVDGKVSVAIE-TDEGHIL--INANDPLPSASLIKIPIMIAAYRQAQ +EGKLNLFSEYSFLPEDRVGGMGVLSHLSPELLTLKDLISLMIMISDNTATNMVIRNV-GM +DTVNQLAADLNCGQTVLVRMMMDH-EAVKRGKDNMTSASDIVRFLKEIVEGSILNEENKK +AVYDTLLNQQF-HTKLPAGFSLHATLAHKTGELP-GTEHDAGIFCFNGK-YAYVAVLTTE +LS-DNASGQRVIAQVGKLVFHY- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. OG2 TaxID=1979526 RepID=A0A231WA86_9BACI +-nQLEKRLADILRQCPGNASLAVEY--GERAI-HMNSGRKYPAASLIKIPIMMEAFFQAE +EGVLDLNEQVRIGGIEKAGGAGIIQSLSVTALSILDCITLMIIVSDNTAANLLIKLL-GK +KNINDRMHGLGLQTTVLGRKMMDFEAA-AKGIDNFTTAADMVKCLRAIKDGELFSEKNRS +KMLDIMEAQQF-REKLPALACKELKIANKTGELP-GLEHDCAIFAS-GRDVLYAAVLIEG +LS-SPEEGNHAIRLIG------- +>[subseq from] serine hydrolase n=1 Tax=Runella sp. CRIBMP TaxID=2683261 RepID=UPI001411F9BB +--------------------------------fSKGPAEPVPSASIIKIPILVELMEQVK +AGKVDLNKTYTLVATDKTGGAGVMASYADGQMSLKEVARLMMIASDNTATNIFIRTL-GR +EKINDRMKLLGLASLQLNRVMMDTAA-VARGIDNYVTARDINALLRLIYSHKVATPALCE +QMMEFLFENRD-TVTLPRLIPKTIKIAHKTGGLTY-VRGDAGIVFAA--TPFVISVFVRG +TPE--KDAEKIIGEIGEICFKIf +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga ginsengisoli TaxID=363837 RepID=A0A2P8GE06_9BACT +-rKLEKGLQELIKGFNGDIGIYVRNLKTGRYV-GIHEDTIFPTASIVKIPILVGVFDKIE +KGELTYHQPLIYRDSIKYGGSGLMQFFKDSTTDLSVLLALMMSYSDNTSSLWNQALAGGG +QRINELMAQYGLSVTRVNSRTPGREDIRNVYGWGMTTPREMAELVVKIRQGEIVSKAASA +RMYRLMTHGYY-DETGLSQIPPYVQAAHKTGSVD-ASRSEVILVNAPHGD-YVFYVGTKN +NKTDENEAENLIRKISKYLWEYf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8RK15_9BACT +---LDRRVRDEAAKFEGTVSLYAKNLDTGAEY-SFGGDERVRTASTIKIAVMIEAYARVA +EGRAKWTDELVLTKEKKVSGSGILQEFSDGLLTLRDAVTLMMVLSDNTATNLVIDVL-GA +DAVNARMQSLGMTETRLMRKIGGGGDSEEGKKEGRTTPHEMVTLLEKLERGEIVSPSVSK +EMIDLMKREQGTDGIWRALWK--TPKATKSGALD-ALRSNIGIIYHTRG-RIALAVTCDD +MPEPDNPAYHLMSRLSEIVI--- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E5GXI5_9BACT +-tSLEETIEKQLQSLDAETSFYAKHLPSGREI-SIRADQPMNPLSVIKIPMMVLAFQDTE +NGQFDLDQRYRIRAEDMRGGSGLLQTFTTGLPTYRDLITQMIITSDNTATDIILNNL-TM +ERVNLFLEENGYLETIVKSSTGDLFRRFEGDSTGRTTAREMGMLLEQIENAELTSRKSAD +EMVNILRRQFY-NSRIPRFLRGKATVGHKTGDWAPHAGNDVGILYYPGG-PSIMAIFTNQ +NKGDFVELEATIGKIAEDIVNHw +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3B8VC05_9BACT +-dSLHAAIHELIARTQGTIGIAYINLQDPSDTlFINADEMFHAASTMKTPVLIEAYKQAA +AGGLSIKDSMLVHNSSIADGSSFSEMHARIGVPIRDILYDMTINSGNLSTNLIIDKV-DA +KKVTQTMRDLGASKIEVLRGVEDMKA-FDAGLSNRTTARDLAIIFQHIANGTAVSQEASN +DMIDILLDQQF-KEMIPAKLPKSVKVAHKTGWIT-GVVHDSGIVILEDGRQYVLVILSKN +LEEN-NLGTEIGADISKLIFEWf +>[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141REZ2_9BACT +------------------------------------------------------------ +------------------------------------------------------------ +--MTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] serine hydrolase n=1 Tax=Veillonella magna TaxID=464322 RepID=UPI0009FC4DA6 +heDAKKAIGQILGDEVSKYGIYAFYP-TADTVpLIIQSRPMRSASMIKVFIMGKAMQEVE +RGRLSLDEMITLKANDKVGGAGIIAGWADGTIPVRELLRLMITESDNTATNLMIDRL-GM +EAINEYIRQEGYGETKLQRKMMDTAAA-EAGRENITSPADLGHFFTRMWKGEGMTAGTRE +QMLTWLYEQTD-TECLPQAFPQG-KIAHKTGELV-GLYDDGGIVVREG-TPLVICIMNDD +ID-SRGGAIRDMQKIAR------ +>[subseq from] Beta-lactamase class A n=2 Tax=Candidatus Kryptonium thompsoni TaxID=1633631 RepID=A0A0P1LV98_9BACT +--EIVSKINQIGKKYGGRLGVSAKNFITGETI-QINADSLFPTASVIKVPILVELFYKFE +EGKLKKDTLISFDDSLKYGGSGVLQYFYDGALKLIDVAVLMIILSDNTATNLVLDCFADL +EAVNNRMKELGLNNTKILNKLMSFKTKKKTPEAGYTTPNDMVKLLELLANGKVINPEISA +EIINIMKNNQD-YEMMKRYLSENVTVANKSGSIDK-MKADIGIVYAKCV-TYAVAIFCDE +LSAVDNKGHLAVAEISKLIFDYf +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A358IGK6_9BACT +------------------------------------------------------------ +---------------------------PGVQLSIHNLLELMLQISDNIATDILFEIAGGA +EEITGRMVEVGADGIRVDRTTWALIAAFNADPQDTATPLAMARLLRKIWDQEILSEKSSS +LLIDIMYRCQTGEARLKGALPPGTQVAHKTGTIGE-TTNDVGIIDLPDGGHVITVVYIKE +SKPDNPAMEPVIANIARAIHDYf +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536AMD4_9CHLR +-----------LDRTRGVTGVVVREVGGATLF-SQRPDEVFPAASVIKIPLVMALYAEAA +DGRLSLEERMPVGA--IVGGTGILGDLRDVRVSLRDLAMLAIALSDNTATNRLIDRL-GV +ARVDERMAEWGCVRTKLARGMFDWDAQ-RRGLENVAAPSEMAALLERLVCGELVDRATSD +AVVAVLERCQD-DAMLRRYLAKGGRVANKTGTLA-ATRNDAAILFGPSRT-IVVAAFMRE +VA--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Rhodothermaceae bacterium TaxID=2026787 RepID=A0A2E3QZG7_9BACT +---LAETVDAIVAQHGATVAVAVRS--PSRRF-DRLADRSFHAASTMKVGVMIEAFRQVQ +AGRRAWDDPVRVENRSIVDGTEYQYALQGRDVTFRTLTERAITTSSNLATNLLIGLV-TA +DSVQATMDRLGAPGLRVLRGVEDLKA-FEAGLSNATTADALATVLEAIRDGRAVSPAADA +EMVDILDDQAF-NEMIPAGLPAGTRVAHKTGWITE-IHHDAAIVYPDGAEPYVLVVLTEG +LA-DHDESARLGAEVARAVH--- +>[subseq from] Uncharacterized protein n=1 Tax=Prevotella sp. P5-92 TaxID=2024222 RepID=A0A255SWS2_9BACT +---------------------------NGELYcGHQEDSAFAMHSVMKFPQALYVADYLH +KKGLTLSDSVLVNKDSLDAWSPMLSIFEGMRFTFAELIEWSLKQSDNNACDLLFASCGQP +DAVEKYIHTLGFKDIHVQLTEKEMKKNPHRAIENSATPKEMARLLEWFYLHRD-DNKNIS +FIWDTMADCNTGQQRIAAVLPKDGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFLQK +SKEEKGVA--------------- +>[subseq from] Uncharacterized protein n=2 Tax=Bacteria TaxID=2 RepID=A0A292QYB0_9BACT +---LKSQLEGLMAQYPIKPAIYVWEYENGKFV-DINGDSLYSAASIIKLPVLIRLFKSIE +AKQMTIYDDMLLTNYYQSPGSGNLQYAQTGRYSLDQLAKTMIQDSDNTSTNMIMAKLGGM +DDINAGLRDWGISKTYVRTWLPDLTGT------NKTTAKDMAKLLYNLDNPGFLNINSRE +YIIDYMSHVKN-NRLIAAGLGDGALFVHKTGDIGT-MLGDAGIVYAQNGKKYIVVILANR +PH-NAPQGKDFIVKASSLIYK-- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium CG12_big_fil_rev_8_21_14_0_65_60_17 TaxID=1973924 RepID=A0A2H0JXZ9_9BACT +--------------------------GTAAEF-HMNGNRLFHAASTMKLPVMIEVFRRAE +RGDFAMDDTIVLRNSSIVDGEPFSYDKLGQPMSLADLTYNMIIVSSNLATNLLIDEL-TA +DSVQATSERLGTTHMKTLRGVEDLKA-FERGMNNQATSHDLALLLTRLMNGTAVNARSDA +AMRQILLDQKF-NEIIPAGLPSDVRVAHKTGQITR-INHDAAIVYPPGDDPYVLVILMEG +IS-DHDASARLGAELARAIH--- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus sp. NW-56 TaxID=2080419 RepID=UPI000CF4DE97 +------------RGYGGEVGLLIHDLAGRELF-SLNADRAFPAASTIKVPLLVQALEEAQ +AGRLDLSARVAMTAQDRVPGSGVLHELDEGLLTWRDVLTLMTVVSDNTATNLLIGQL-GV +ERVNAWLDKRGLTSTRLVGPLPRQTEAQRRGERNRTAARDQVALLGQLARAELLDPPHTE +LALSILARQQF-RDLLGRYVPRDYRVASKSGELR-GVHHDVGVLFTP--RPLVVALLSQG +GTDPRE----------------- +>[subseq from] Uncharacterized protein n=1 Tax=Sphingobacterium paucimobilis HER1398 TaxID=1346330 RepID=U2IY46_9SPHI +--KLEQKLKQEITHFQGDIGIYVHQLKSNKIV-AINADTIFPTASIVKVPILAGVFQKIA +QGELKLEQPFQYSDKRAYGGSGLMQFYKDSATDLSTMISLMLTYSDNVTSIWLQELAGGG +AQINPLMDQLGLTHTKVNSKTKGREKIWEEYGWGQTTPREMAKLFTLIRNGAVIDPRHSD +KMYRYLKNQFY-NERSLSQIPAWVSTIAKTGSVDR-ARGEVVLVNAPGGD-YVFCILTKN +NQTDKNEAEELTRRLSSIIWNHf +>[subseq from] serine hydrolase n=1 Tax=Actinomadura atramentaria TaxID=1990 RepID=UPI0009FDF764 +------AIEDAFRAAGVTGWLCALDIDGGRGV-AVRGDEPVVLASVFKVPLLVAFFRRAA +AGLLDPAEAVTLRPADRSDGPTGTSVLLDDVMSLRDLAAMMITVSDNAAGDVLYARV-GR +DEVNRAMADLGLTATHIASDGRELAAALDPLRTSRSTPREMAALLAAVWRDEAAPPAECA +LMRRMLGLQVW-PHRLSSGFPDDVRVSGKTGTLPT-VRNEIGVVEYPDGGRYAVAVFTRA +LRAVLPQADAVIGAAARLAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga sp. S165 TaxID=2135462 RepID=A0A317LYG9_9BACT +-rKLEKGLRELIKGFNGDIGIYVKNLKTGRYA-GINEDTIFPTASIVKVPILVGVFDKIE +KGELKYHQPLIYRDSIKYGGSGIMQFFKDSTTELSVLLALMMSYSDNTSSLWNQALAGGG +QRINELMEQYGFSVTRVNSRTPGRAEIRNIYGWGMTTPHEMADLVAKIRKGEIISKAASE +RMYRLMTHGYY-DETGLSQIPPFVQAAHKTGSVD-ASRSEVLLVNAPHGD-YVFYVGTKN +NKTDENEAENLIRKISKYLWEYy +>[subseq from] serine hydrolase n=1 Tax=Nocardia thailandica TaxID=257275 RepID=UPI0002DE1B33 +-----------------------------GEV-DLGGRERVVTASVYKLLVFTAYCRLVD +QGALDPRARLTVDPARCTPPTGLAALRDPVTLSLRDLAASMMTVSDNAAADILLDLV-GP +AAVAALAAEQGLTATRVVGGMAQVHEAYDPAYASATTPEEMTRFLRALWTGAVLSPAGTA +TVREVMGAQVW-PHRIAAGFPPGVRVAGKTGTIG-AIRNEVAVVEFPGEHPVAVAVFTRA +ARPQLAVVDAAIAETARLAVT-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 47-3 TaxID=2486013 RepID=UPI0013DE4AF9 +--QLQQIAQKTVLAVPGTNSVYVKKFATAGTY--VANNRPQRAASVIKLFIMATAFQQIA +AGKFTLNEPYTLTAADKVGGSGVMQGSVGTKVTLAQVMQYMMDDSDNVASNIMLAKVGGL +AAVNAECRHIGTKDTIMARKLMDMQA-LAAGHDNMTSVADLGKLLSKLYQHRLVSPAADT +QMLALLAQNKN-HTKLPAQLT-GAKVYNKTGEFDYGVQNDAAIIANDHGA-FVAVVLAQG +GAQQAQ----------------- +>[subseq from] Putative beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=D1PHG0_9BACT +---------------------------NGDLYcGHQEDSAFAMHSVMKFPQALYVADYLH +KKGLTLSDSVLVHKDSLDAWSPMLSIFEGMRFTFAELIEWSLKQSDNNACDLLFASCGQP +DAVEKYIHTLGFKDIHVQLTEKEMKKNPHRTIENSATPKEMARLLEWFYLHRD-DNKNLS +FIWDTMADCNTGQQRIAAVLPKDGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFLQK +SKEEKEVAEI------------- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rhodococcus sp. TaxID=1831 RepID=A0A520EH61_RHOSO +------------------------------------------------------------ +----------------------------------------------------------GT +AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLAQASRQ +QLLDWMAGNQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT +TSEDSPAMNALVADTTRTVVEQ- +>[subseq from] Beta lactamase n=1 Tax=Nocardia cyriacigeorgica (strain GUH-2) TaxID=1127134 RepID=H6R1V2_NOCCG +--EVTDRIRAVFADAGCTGWLHARRCGSPAEI-SVDAHDRVVIASVYKLVLLVAFCRRVD +AGLIDPRAPLTVHPADCTPPTGIAALHDPVTMSRRDLATSMMTVSDNAAADVLLGEI-GL +GAVEELLTELGLTETRIVGGTADVHRAYDPSYASATTPEEMTRFLDLIWAGGVLSPEQTG +FVRAVMGKQVW-PHRIASAFPRGVGVAGKTGTIGV-IRNEVAVVEFPDEYPVAVAVFTRA +ARADLAVVDAAIAEAARIAVT-- +>[subseq from] Uncharacterized protein n=1 Tax=Selenomonas sputigena (strain ATCC 35185 / DSM 20758 / VPI D19B-28) TaxID=546271 RepID=C9LUU8_SELS3 +--ALVDEVRRLAARGGAKFTVYLADPDDGNAP-LIRDADEMRAASMIKVFILACAMEKVK +AGELHLDDVLRLEEVDKVGGAGVITGYRAGTFSVEELLRQMIAESDNTATNMMIDRL-GM +TEINGYMRAHGYDASRLQRKMMDD-AAVKEGRENITSAKDLGTFFLRLYRSECVGEPYDG +KMRDMLFAQTD-RECFPQALP-GARIAHKTGELDR-LYADGGILYGEDGRAVILVILADD +IE-RRGRAIEMMREIARRVMQ-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces alboflavus TaxID=67267 RepID=A0A1Z1WGE4_9ACTN +-------LQDAFAEAGVTGRLHAVDIDSGAEV-GVGADQPVVTASVHKLCVLVTLHEQAA +AGRVDLTEQIECPPEDRTSGPTGLAAMLDPVMSLRDAAYLMMAVSDNTAAELLLERV-GL +DAVNATTARLGLTRTRAVHSFREMFAALDPARTNHSTPRDMTRLLGAVWRDEACTPEHGA +AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA +ARATLPSADAVIGTAARIAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Blastocatellia bacterium TaxID=2052146 RepID=A0A3D0P216_9BACT +--SLDERIKAEIGDFKGKVWIYAKNLDTGKEY-GMRADEQVRTASTIKLPIMLEVYRQVA +EGKIAWTDPIEITKAVKVGGSGILFEFTDGTIDVKTAMTLMIVQSDNTATNVILDKV-SS +NSVNDFMAKLGLNDTLSLRKIGGGGDAKAWDEPGRSSPRDMVKLLEMLEKGEVVSKEASA +EMIAILRRQQY-KDGIGRNSLDTVPVASKSGSLDR-LRSDVGIVYTRRG-RIAMAITVDD +M---------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Dehalococcoidia bacterium TaxID=2026734 RepID=A0A349K9F1_9CHLR +-kQLETTLKDKITTFDGVAGLSVKSLTSGKSI-SINGDEVFPTASTIKIHVLAKLFSLQE +EGEIDLSQRIRFTQNMYGSGSGVIHFLENDPFTILDVAILMMLASDNTATNTCIDVA-GM +EGINDLIRDMGLSKTKLRRKMMDPE-AINRGDENVSTPNELILMMDLLHNEKP-TPKVSA +QVLRIMSKPKS--AYLNKAVGSKVVVANKPGGMDK-VRGDTGIVYLPNN-PYAVSIMSKF +SMVDSVAQEGFLIDLARNI---- +>[subseq from] Uncharacterized protein n=1 Tax=Aneurinibacillus migulanus TaxID=47500 RepID=A0A0K2WIW9_ANEMI +-kQLDAYISRLIEETCGTWGIVIEDLDEDKRW-EWNTQESFLAESIIKVPVMAAAFAAVE +KKQFHLHDYVCLKKEDMVGGTGVLQHLTPGVLTIYDLITLMIIQSDNTATNIVIDLV-GM +ECIQETLEELGMEKSQFHRKMMIYPVH--IESKNVITADDASTLLKKLATGTFRSRHACE +QMIQILKKQQI-CNGLSSMLPPGWEFASKSGWDDD-RQHDIGILYTGQR-TFTISALSKG +GN--SLQAKQVLGKIGLVVFEY- +>[subseq from] Uncharacterized protein n=1 Tax=Halomonas sp. BC04 TaxID=1403540 RepID=W7Q0U5_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +-RLRWFARRLGIERDSLQPSLEEAFRAYYATGLNGGRLDAFAELLVALGEGRALGTEATA +ELLAILSRTSSGERRLKAGLGRDIRFAHKTGTQHR-RACDAGIASHGEGPQRAVVVACTR +GVLDVARSEQMLAAVGRAIYE-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. ZZV12-4809 TaxID=2575830 RepID=UPI001357E0B1 +----KAGTLKLASSCEGRVALYIHT-E-DGFI-EKSADAVFSSASLIKVPILLAGLLQAE +KGLLQLEDEVEVTASARVGGSGVLQAMARDLIKVTDLLTLMIIVSDNTATNLIIELL-GM +EKTNQLIKTLGFNNTSLNRKMMDFA-ALKKGTDNTTTARDMAYGIKALAEQKLLSGKYTE +KALYILENQQFKNKLANTIETEKIKVASKTGELP-GIEHDCAIFTHKGK-TVYAAVLVDR +LE-NQSTGKKVLSAIGNRISQ-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces alboflavus TaxID=67267 RepID=UPI000B429EA6 +-------LQDAFAEAGVTGRLHAVDIDSGAEV-GVGADQPVVTASVHKLCVLVTLHEQAA +AGRVDLTEQIECPPEDRTSGPTGLAAMLDPVMSLRDAAYLMMAVSDNTAAELLLERV-GL +DAVNATTARLGLTRTRAVHSFREMFAALDPARTNHSTPRDMTRLLGAVWRDEACTPEHGA +AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA +ARATLPSADAVIGTAARIAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium yanglingense TaxID=1437280 RepID=A0A4R6WCR9_9SPHI +-qKLEQKIKKEIAGFRGDIGIYVHQLKSNKFV-AINADTVFPTASIVKVPILAGVFQKIA +QGELKLEQPFTYSDKRAYGGSGLMQFYKDSATDLSTMISLMLTYSDNVTSIWLQELAGGG +AQINPLMDQLGLTHTKVNSRTAGREKIWEEYGWGQTTPQEMAKLFTLIRNGAVVDARHSD +KMYRYLKNQFY-NGRSLSQLPAWVNTIAKTGSVDR-ARGEVVLVNAPSGD-YVFCILTKN +NQTDANEAEELTRKLSSIIWNHf +>[subseq from] Penicillin-binding protein transpeptidase n=1 Tax=Acinetobacter sp. CAG:196 TaxID=1262690 RepID=R5SXM2_9GAMM +---LKSQLEGLMAQYPIKPAIYVWEYENGKFV-DINGDSLYSAASIIKLPVLIRLFKSIE +AKQMTIYDDMLLTDYYQSPGSGNLQYAQTGRYSLDQLAKTMIQDSDNTSTNMIMAKLGGM +DDINAGLRDWGISKTYVRTWLPDLTGT------NKTTAKDMAKLLYNLDNPGFLNINSRE +YIIDYMSHVKN-NRLIAAGLGDGALFVHKTGDIGT-MLGDAGIVYAQNGKKYIVVILANR +PH-NAPQGKDFIVKASSLIYK-- +>[subseq from] serine hydrolase n=1 Tax=Candidatus Gastranaerophilales bacterium TaxID=2137880 RepID=UPI00101BAD31 +---LKSQLEGLMAQYPIKPAIYVWEYENGKFV-DINGDSLYSAASIIKLPVLIRLFKSIE +AKQMTIYDDMLLTDYYQSPGSGNLQYAQTGRYSLDQLAKTMIQDSDNTSTNMIMAKLGGM +DDINAGLRDWGISKTYVRTWLPDLTGT------NKTTAKDMAKLLYNLDNPGFLNINSRE +YIIDYMSHVKN-NRLIAAGLGDGALFVHKTGDIGT-MLGDAGIVYAQNGKKYIVVILANR +PH-NAPQGKDFIVKASSLIYK-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium gobiense TaxID=1382456 RepID=A0A2S9JSF2_9SPHI +--KLERMLQKEIKDFQGDVGIFVQHFKKNKTV-AIHADTLFPTASVVKVPILVGVFDKIE +RGQLKLSDAHIYDADRIYGGSGLMQFYKDSSTNLSTMVSLMLTYSDNVTSIWCQELAGGG +TAINQLMDKLGLPNTKVNSRTAGRQEIWEKYGWGQTTPREIVQLMTMIREGKAITPRLSD +KMYRYLKNQYYNG-EALSQLPAHIATASKTGALNQ-TRNEIVFVHAPSGD-YAFAVLTKN +NNTPDNEAEVLIRKISNILWNYf +>[subseq from] Uncharacterized protein n=1 Tax=Flammeovirgaceae bacterium TMED32 TaxID=1986681 RepID=A0A1Z8QBS3_9BACT +-eDLDSKIINLLEQVEGDFAIAFQDLNRRENVfLLNENKQFHAASTMKVPVMIEMYHQAS +QGQFSLTDSILVKNESIVDHSTYKYTQIGKQMTLFDLMHQMIISSSNLATNILVEEV-GA +KNITASMQRLGAYDTEVLRGVEDQK-AYDLGLNNMTTAKDLMTILKSIALPLGETTQDQI +AMIDVLKAQEF-NDIIPRFLPVDVQVAHKTGSIT-GLHHDAGIIYLPNGETYVLILLSKN +LK-DFDQGTLTLAKISKLFYEHf +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gastranaerophilales bacterium HUM_11 TaxID=1916216 RepID=A0A292RR97_9BACT +---LKSQLEGLMAQYPIKPAIYVWEYENGKFV-DINGDSLYSAASIIKLPVLIRLFKSIE +AKQMTIYDDMLLTDYYQSPGSGNLQYAQTGRYSLDQLAKTMIQDSDNTSTNMIMAKLGGM +DDINAGLRDWGISKTYVRTWLPDLTGT------NKTTAKDMAKLLYNLDNPGFLNINSRE +YIIDYMSHVKN-NRLIAAGLGDGALFVHKTGDIGT-MLGDAGIVYAQNGKKYIVVILANR +PH-NAPQGKDFIVKASSLIYK-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gastranaerophilales bacterium HUM_3 TaxID=1916217 RepID=A0A292R422_9BACT +---LKSQLEGLMAQYPIKPAIYVWEYENGKFV-DINGDSLYSAASIIKLPVLIRLFKSIE +AKQMTIYDDMLLTDYYQSPGSGNLQYAQTGRYSLDQLAKTMIQDSDNTSTNMIMAKLGGM +DDINAGLRDWGISKTYVRTWLPDLTGT------NKTTAKDMAKLLYNLDNPGFLNINSRE +YIIDYMSHVKN-NRLIAAGLGDGALFVHKTGDIGT-MLGDAGIVYAQNGKKYIVVILANR +PH-NAPQGKDFIVKASSLIYK-- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. CH30_1T TaxID=2604836 RepID=A0A5A9E524_9BACI +---LEERILDAIDKCIGRVSVAI-DLPS-HSI-QFNNDTPYSAASLIKVPILLEGFRQAE +QGKIDLNEMVMVPKECRVGGAGVLSTLSENILTVEDLLTLMIIVSDNTATNLIIDRI-GS +EAINNLCNSLALKHTKLSRKLMDFQ-AIDQGYDNFTSATDIINCLRILDQSPLFSEQSRE +KMLFILHQQQF-VTKLPARMDERVFIANKTGELP-GVEHDCAIVRCEEKT-AYIAVLIDG +LEEN-DSARDTIAKIGKFLYDY- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8NKH9_9BACT +---LDRRVRDEVAKFEGTVYLYAKNLDTGAEY-SFGGEERVRTASTIKIAIMIEAFARVS +EGKAKWTDDLVLTKEKKVSGSGILQEFTEGLLTLHDVVMLMMLMSDNSATNLVIDALGGA +DTVNARMQSLGMTDTRLMRKIGGGGDSLEGKKEGRTSPREMVMLVEKLERGEIVSPAVSK +EMIDLMKREQTQDGIWRELWR--LPRATKSGALD-ALRSNVGIIYHPRG-RIALAITCDD +MPEQNWTA--------------- +>[subseq from] Serine hydrolase n=1 Tax=Gramella sp. KN1008 TaxID=2529298 RepID=A0A4Q9V6P2_9FLAO +--ELDRSLEQLTRDFNGTVGVYVYNLETRQEA-GINSDSIFPTASIVKVPILAGLFDKIA +KGEFTLNDTLVYEAKRAYGGSGLMQFYKDSTTDLRTLAALMITYSDNTTALWCQELAGGG +EDINEVMKELGFRYTRVNSRTKGREEDWKKYGWGQTTPREMASLLFKIYDRQVVNPASSD +EMYRMLTNSFY-TDYALSQIPPYVQTAAKQGMVDR-SRSELVMVNAPNGD-YVFYIATKG +NKDNDNEAWKLHRKISAFLWNYf +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 47-3 TaxID=2486013 RepID=UPI000F76C7ED +--QLQQIAQKTVLAVPGTNSVYVKKFATAGTY--VANNRPQRAASVIKLFIMATAFQQIA +AGKFTLNEPYTLTAADKVGGSGVMQGSVGTKVTLAQVMQYMMDDSDNVASNIMLAKVGGL +AAVNAECRHIGTKDTIMARKLMDMQA-LAAGHDNMTSVADLGKLLSKLYQHRLVSPAADT +QMLALLAQNKN-HTKLPAQLT-GAKVYNKTGEFDYGVQNDAAIIANDHGA-FVAVVLAQG +GAQQAQ----------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Lactobacillus mixtipabuli TaxID=1435342 RepID=A0A1Z5IA31_9LACO +--------KKCVTSASGDTSVYVSNLKTRQPV--IMNSQSQRSASVIKLFVMVETFRQIK +AGRLSLNQAVQISKSDRVGGTGELAQQNVSQLTVQRLLTLMIRNSDNSATNALIDQLGGL +NVINGEIKRLGCSDTQLQRKMLDYQ-ALKNGKDNQTSVKDVGSLLTKLYQHRVLGAPYDS +EMLQLLRYNAN-QSKIPALINQKATVYNKTGEFDYGVQNDAAIVKKGNQA-FVAVVLSQN +GTE--NKQISAMQQLGQALY--- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga filiformis TaxID=104663 RepID=A0A1G8A514_CHIFI +-rKLEKGLRELIKDFNGDIGIYVRNLKTGRYV-GINEDTIFPTASIVKIPILVGVFDKLE +KGELKYHQPLIYRDSIKYGGSGLMQFFKDSTTDLSVLLALMMSYSDNTTSLWNQALAGGG +QRINELMAQYGLSVTRVNSRTPGREAIRNIYGWGMTTPHEMAELVVKIRQGEIISKAASE +RMYRLMTHGYY-DETGLSQIPPYVQAAHKTGSVD-ASRSEVILVNAPHGD-YVFYVGTKN +NKTDENEAENLIRKISKYLWEYf +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535X4L3_9CHLR +------------ATLPGEAGAYACDEDGRELF-GEGANELFPSASVIKLPLVMTLYADAA +RGLADLDERVEVGT--RVDGSGVLRHMRDAAMSLRDYAMLAVIVSDNTATNRLIDRI-GT +ERVNERMREWGCPLSRLERRMYDFEAA-RAGRENVMTPRETASLLLRLVRGECEDRATSD +AVLAILAQCQD-RTMLRRYLPYTAIVANKTGTLDE-SRNDAAIIRGE--RAVVVAAFTKE +LRDTEA----------------- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8T3Y5_9BACT +---------------------YIKCIETGEEI-AINADETMDTMSVIKIPLMAEVFRQIE +AGKFALTDRVTLKEAEKRPGTGVIRSLDAGALTIKDLITLMIIVSDNTATDMLFEKVGGT +DPVNKLMQSYGLNTIKATGPTDVWFKTEGKTPFGLSSPRDLGKLLEKISRGEAVSKQASD +QMLRIMRGQLY-SSRLPKYIT-GFGIPHKTGDFLPYIGNDVGILESANR-HIVISVFTAR +HNGIGPNMEDAIGRIAEQVANFf +>[subseq from] Uncharacterized protein n=1 Tax=Atopobium vaginae DSM 15829 TaxID=525256 RepID=F1T3K7_9ACTN +-kELQQQIEELTQPYGSSVSVCIIDASNGNYC-HVNSDKAFVSASMIKLAVLCEYMHAVD +NGQLDPADRVTLKNMKVVGGTGLIQTERHASYSYDELCRYMIMYSDNTATNVLINKL-GQ +DAINERVQALGCKNTSLNRQLMALNTN----TENWISARDAATILYKFKNGTAASSTICA +KALEYLSKQTD-NEGMAEGISSG-AFAHKTGSLRS-MRHDGGIVLG--KHPYVIVALCDI +GAGN---ANRLMKEIAQ------ +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5V3D7_9BACT +--SLRNELEKIAGESKARISVAVLDLESGFRF-SLAGDRWFHAASTIKVAVLLAIFRAAD +EGRLRLDDPLHVRNRFLSIGFPFRYRAIGRTVKISALAEGMIAASSNLATNLLLDFV-GV +EYARNVLRDAQVSGVELRRGVQDENA-HERGIDNEVTADGLLALLCAV-RGDFLKQQSRE +EIIRILLAQRF-NSMIPAGLPPHATVAHKTGEIST-ACHDAGIVYLPEREPYIVVILTEF +DA-EKDGRYQTLVGISNLIYR-- +>[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora sp. HAJB-30 TaxID=2715536 RepID=UPI00140A337F +--ALRAELETLATTSPGRWAFAVRE--SGHQLaSVNGDTVMPAASTIKVALMLFVLRDIA +VGRRSLDDVLDVP-DVRAGGAGVLNALPSVRLRLDEVVELMIVVSDNTAANMIIDLL-GA +PALDKRLAELGTTHTRLQRRLMDLEAA-KTGLRNVTTADDQALLLDRLVGPGLLPPELRE +LALGVLGRQQF-NDRMPARLGADVVCRHKTGEIT-GVRHDVGVLEFDGRQ-VVLAALGSE +LDERPGPAADIIAEAAATVV--- +>[subseq from] serine hydrolase n=1 Tax=Chitinophaga sp. O9 TaxID=1233460 RepID=UPI00136A4588 +---LYNVLKPLLDAHHGDAGVYVQHLKTGRTV-AINADTVFPTASMIKIPILAGVFKRIG +EGGLQYRQLLTYRDSLLYEGEDLLGSFRDSQITLDKVVMLMLTMSDNTASLWLQSLAGGG +AVINEWLAQQGFEHTRVNSRTKGREENRRIYGWGQTTPREMATLMKRIYKGEVVSKAGSE +RMYRNLTRNYW-DTEGVLMIPPGIRTASKNGAVDE-SRSEVLMVNAPHGD-YVYCIITKN +NKNRDNEAWQLLRKVGAAIWHHy +>[subseq from] Uncharacterized protein n=2 Tax=Candidatus Gastranaerophilales TaxID=1906119 RepID=A0A292SCK1_9BACT +---LKSQLEGLMAQYPIKPAIYVWEYENGKFV-DINGDSLYSAASIIKLPVLIRLFKSIE +AKQMTIYDDMILTNYYQSPGSGNLQYAQTGRYSLDQLAKTMIQDSDNTSTNMIMAKLGGM +DDINAGLRDWGISKTYVRTWLPDLTGT------NKTTAKDMAKLLYNLDNPGFLNINSRE +YIIDYMSHVKN-NRLIAAGLGDGALFVHKTGDIGT-MLGDAGIVYAQNGKKYIVVILANR +PH-NAPQGKDFIVKASSLIYK-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. Akac8 TaxID=2563106 RepID=A0A4S3GH18_9ACTN +----VARIHAALADAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCVLVALHEQAA +RGALDLAEQVECGPKERTAPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTARLGLTRTRAVHSFGEMLAALDPERTNRSTPRDMTRLLGAVWRDEACTPEHGA +AIRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] hypothetical protein n=1 Tax=Luteitalea pratensis TaxID=1855912 RepID=UPI0012FF688D +------------SSVDGSVAYLVVDVTSGQRF-ARRADEPFPTASAIKIGILYELFVQVD +AGREVLDDPKPLPEASRAGGSGIINRLRSPVLSLRDHALLMILLSDNTSTNVLIDTL-GM +DAINAHMQALGTSGYRLRRRMMDSAAAARG-DENVASASDLVTVMDAIRTGRGLRPESQA +EAIRILREY--GPTSVRAGIPADVPVATKPGGLD-GVRSEVSWVDVKGR-PYLLCVMTSF +LA-DDQAGEKAITEISRTSYQYf +>[subseq from] serine hydrolase n=1 Tax=Anaerosalibacter massiliensis TaxID=1347392 RepID=UPI0005B2BFAE +----KEDLIKLCKDIPGDIGFYYKDIKSKKVI-SFNENQLFIAASVIKIPVLVETLKQVE +NGNINKDHKVKVLKKYKVPCGALTYMHDDLEVTIEDLYTLMIIHSDNTATNMLVDML-GM +ENINNTLKDLGCNNSKINRLLFDAKAQ-NEGIENYITPYEIGYLLEKIYDGEIISKSISK +EIERILKLQRL-NHKMPYLLPQNIEIGHKTGEDC-GITHDVGIVYSK--KPFIFCFASNN +ID--VIKAEDLLRKMAFICY--- +>[subseq from] serine hydrolase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000990FCDB +-----QSVEEIINSTQARISIAVE-IDEQRII-EKDSDREYLSASLIKIPIMMEAYRQSE +LGTICLTDLIEIKDFQKVGGSGVLHSLTGGTLSIKDLITLMIIVSDNTATNIMIELL-GK +DNINQFCRDIGAHHTKVERKLMDEQA-KAKGYENITTASDMICLLKELDQNEILSKNSTL +DILKCLSAQQF-RHKLPGLMDQDMKIANKTGEME-GIEHDVAIIHYGGK-KAYIAVLIDQ +LEQN-FLGQVSITKIGESVYEY- +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5JDE7_9BACT +--TFNEEVERLSAGSKARIAVAVHDFQSGSRF-SLRGDRWFHAASTIKVAVLLAIFRAAD +EGRVHLDDSLHVRNRFISAGFPFHYQLVGRTAKISTLAEGMIAASSNLATNLLLDFM-GV +EYARKVLRDAQVDGVELRRGVEDYA-AHERGINNEVTADGLVSLLSAV-RGDFLRNESKE +QAIRILLEQRF-NSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EGNGRREIVATISVAIYR-- +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium 13_2_20CM_55_10 TaxID=1805420 RepID=A0A1Q6VBA5_9BACT +-------------------AVAVHDLESGLRF-SLEGDRWFHAASTIKVAVLLALFRAAD +EGRVRLDDSLHVRNRFISAASSFHYQAIGRTAKISALAEGMIAVSSNLATNLLLDLV-GV +EYARKVLRDAQVEGVELRRGVED-HAAHERRINNEATANGLLTLLSAL-RGDFLSSESKE +QAIRILLEQRF-NSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DL-EQNGRRETVAAISEAIYR-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A354YKF0_PSESP +------------------------------------------------------------ +-------------------------------------------------ANLLFGVVGGP +PEVTAFRRASGDTVSRRDRLEPGLNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ +QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA +GAISYEQRASVLAQVGRIA---- +>[subseq from] Serine hydrolase n=1 Tax=Caulobacter flavus TaxID=1679497 RepID=A0A2N5D1W6_9CAUL +heAMSHKLTAIAERAPGDLGVAVQDLSTAQRA-AVAGEQLFPLAGIWTAALGAAVLAEVE +AKALSLRETLTIDDVDLSPPSGVADAWPGRRWTVEDLLKRAVAGGDNTAADVLMKRIGGP +GAVTAWLDLKKVENFRVDRYARQLTPDYLADPHDTTTPLAAVRFLEALNQGELSGQEGRR +RLLRIMEAAA--GDRLRPALPAGARLAAITSATSTAADNTLAMVRLKDGRRFALAIFLKA +SPLEESDRDALVLEVMRTVLQ-- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus murrayi TaxID=68910 RepID=UPI0009FEE0BD +------------RGYGGEVGLLVTDLAGTELF-ALNADRSFPAASTIKVPLLVQALEEAQ +AGRLDLGARVCLQAEDRVPGSGVLHELDPGLLSWRDVLTLMVVVSDNTATNLLLDRL-GL +GAVNAWLLERGLSGTRLQQPPERQNAAQRRGERNRTTPRDQVRLLGQLARGELLDAPHTE +LALSILARQQF-RDLLGRHVPRDYRVASKSGELR-GIHHDVGLLLTP--RPLVVALLSEG +GTD-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8TXG8_9BACT +-eTLDEKIRAAIAGFPGTVSLFAKNLDSGATY-GLHPDERVRTASTIKLPILAATFAAVQ +EGKVKWADLSTLHDSDKVSGSGVLGEFSDGVLPLADLAHLMIVVSDNTATNLVLDRI-TA +DYVNEQMDKLGLKATRAMRKVRGDGAENQRFGLGSSSPREMVTLLEKIERGEVVSAEASR +EMLKILKRQQD-HNGIARRMG-DMPVANKAGALDH-LRSDVGIVYSPGGR-IAMAITCED +IP--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. Mgbs1 TaxID=2485489 RepID=A0A433WC53_9BACT +--RLYNVLKPLLDAHHGDAGVYVQHLKTGRTV-AINADTVFPTASMIKIPILAGVFKRIG +EGGLQYRQLLTYRDSLLYEGEDILGSFRDSQITLDKVVMLMLTMSDNTASLWLQSLAGGG +AVINEWLAQQGFEHTRVNSRTKGREGNRRIYGWGQTTPREMATLMKRIYKGEVVSKAGSE +RMYRNLTRNYW-DTEGVLMIPPGIRTASKNGAVDE-SRSEVLMVNAPHGD-YVYCIITKN +NKNRDNEAWQLLRKVGAAIWHHy +>[subseq from] serine hydrolase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013D83C4C +---VTDRIRAVFADAGCTGWLHARRCGSAAEI-SVDGRDRVVTASVYKLVLFVAFCRRVD +AGLIDPRAQLTVDPADCTPPTGLAALHDPVTMSRRDLATSMMTVSDNAAADVLLGEI-GL +GAVEDLLDELGLTETRIVGGTADVHRAYDPSYASATTPEEMTRFLHLVWEGGVLSPEQTG +FVRSVMGKQVW-PHRIAAAFPRGVSVAGKTGTIGV-IRNEVAVVEFPAEYPVAVAVFTRA +ARADLAVVDAAIAEAARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Ignavibacteriales bacterium CG07_land_8_20_14_0_80_59_12 TaxID=1974045 RepID=A0A2M6YX28_9BACT +-dTLEESIAALAGTFGGRIGVAARDLKTGRTI-LVDADSLFPTASVIKLPVLVALFDKFR +TGALHPDDTVSLTDSLKYGGSGVLQFFSGDALKLIDAAMLMIVLSDNTATNLVIDTFARL +AAVNSLMERFGLKHTHLLNKVMSWKTKTPESIRGVSTPADMLLLLERITAGTAVDSASSR +QMFDIMKNQQD-VTMAARMLPEQIVVANKTGWVSE-TKVDVGIVSSPAT-RYAYAIFADN +STDTDNRAVLAVARASRIIYDAf +>[subseq from] Uncharacterized protein n=1 Tax=Novibacillus thermophilus TaxID=1471761 RepID=A0A1U9KBT0_9BACL +---LEKRICETIKDYRDRFFIAIST--DEGTI-QLNADRQVRAASVVKVPIMIEAFRQVE +AGSVELDQPIDIDEGSKVGGCGVIKYLTRSNFTFRNLLELMVIVSDNTAANLVLDKV-GV +NSVNQLFEQLGCRNTQIERKFMDAE-AIEAGRDNYTSASDMVTLLKIIGETNAITQSSRS +QMLEILSRQQF-RQKLPCYSDSGVRFYNKTGEIP-GVEHDVAIVQRG-KARIYAAVLTQG +WQN-NGMAQRYLAEIGKHLIA-- +>[subseq from] serine hydrolase n=1 Tax=Terrimonas ferruginea TaxID=249 RepID=UPI00041E4A75 +-kKLETRLREAVSGFNGDIGIYVKNLKTGKIA-VFNADTVFPTASIVKVPILLGVMQKLE +RGELFYDSTITYRDSLLYAGEDILGSFKDGEIRLKKVMMLMMTTSDNTASLWLQGLAGGG +TRINQLLDSLGFKDTRVNSRTPGREDIRKIYGWGQTTPKEMGEIFERIYRNQVFSPAACD +RMMRCMGRNFWDQEEAISVIPPYIEVFSKNGCVDQ-SRNEALLVNAPNN-PYIFCIFTKN +NKRKSNEAWTLTRKISTMLWEYf +>[subseq from] Serine hydrolase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=A0A5R8NCB6_9NOCA +---VTERIRAVFADAGCTGWLHARRCGSAAEI-SVDGRDRVVTASVYKLVLFVAFCRKVD +AGLIDPRAQLTVHPDDCTPPTGLAALHDPVTLSRRDLATSMMTVSDNAAADVLLGEV-GL +GAVEDLLDELGLTETRIVGGTADVHRAYDPSYASATTPEEMTRFLHLVWAGGVLSPEQTG +FVRSVMRKQVW-PHRIAAAFPRGVAVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLAVVDAAIAEAARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. RM TaxID=2316359 RepID=A0A418QGL5_9DEIO +------------SGFPGAVGLRVTDLSGTELV-AWNADRVFPAASTIKVPLLVFALQEAQ +AGRLDLSARVTVQPGDRVPGAGVLHDLDGGLLTWRDVLTLMIVVSDNTATNLVIGRL-GV +DAVNAWLAAQGLTGTRLVGKLEQRNEAQRRGERNATTARDQTALLRALVAGEVLDGAHTA +LALDILGRQQY-RDLIARHVPCGYRSATKSGELL-GVHHDVGVLFTP--RPLLVALLSGG +GADPR------------------ +>[subseq from] Putative beta-lactamase n=1 Tax=Symbiobacterium thermophilum (strain T / IAM 14863) TaxID=292459 RepID=Q67P40_SYMTH +--DLTAILERVVSDLPGTIGVYVTDLATGRSA-GLNPMAEFYAASTIKVPIAMAVLWLAD +RRRISLDQTIAYQPEDYQAGTGILQATIQPGVSVRRLLELTITVSDNIARNMLERFI-GS +GTIRNYMLSLGVAPA-YDP----LET--------PVTPYGMNQVLIALDSGRGLSPASTR +MLLRWMEEAVF-RRRIPRYLPESAVVATKIGSRDD-EFHDVGLVYAPDR-SFAISVFTKG +MT--EAQAEEAIARIAEAVYW-- +>[subseq from] serine hydrolase n=1 Tax=Novibacillus thermophilus TaxID=1471761 RepID=UPI000989C41F +---LEKRICETIKDYRDRFFIAIST--DEGTI-QLNADRQVRAASVVKVPIMIEAFRQVE +AGSVELDQPIDIDEGSKVGGCGVIKYLTRSNFTFRNLLELMVIVSDNTAANLVLDKV-GV +NSVNQLFEQLGCRNTQIERKFMDAE-AIEAGRDNYTSASDMVTLLKIIGETNAITQSSRS +QMLEILSRQQF-RQKLPCYSDSGVRFYNKTGEIP-GVEHDVAIVQRG-KARIYAAVLTQG +WQN-NGMAQRYLAEIGKHLIA-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus obstructivus TaxID=1914540 RepID=A0A1L8ZGR2_9BACI +-----QSVEEIINSTQARISIAVE-IDEQRII-EKDSDREYLSASLIKIPIMMEAYRQSE +LGTICLTDLIEIKDFQKVGGSGVLHSLTGGTLSIKDLITLMIIVSDNTATNIMIELL-GK +DNINQFCRDIGAHHTKVERKLMDEQA-KAKGYENITTASDMICLLKELDQNEILSKNSTL +DILKCLSAQQF-RHKLPGLMDQDMKIANKTGEME-GIEHDVAIIHYGGK-KAYIAVLIDQ +LEQN-FLGQVSITKIGESVYEY- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. SYSU G01002 TaxID=2652445 RepID=UPI001291ABED +---LKEEILRLVSQCDGRVSVRIEL--NGEAI-DIKGNNVYSSASLIKIPILLEGFRQVE +AGKLQLDRVYELKDEEKVGGAGVIQALHGQNYSLLDLMTLMIIVSDNTATNRLIDII-GM +DSINSCISSLDLKHTVINRKMMDFIS-LQQGKDNLTTAADIVACLRKIEDASFLTPDSRE +KILGILHHQQL-LDKLPVLIDKEIWIANKTGELP-GVEHDCAILKYKGK-TLYVAVLVDQ +LR-DKKAGRAVISEIGKM----- +>[subseq from] Serine hydrolase n=1 Tax=Blastocatellia bacterium TaxID=2052146 RepID=A0A352FLS7_9BACT +-nSLDSQIRAEISPFKGKVFVFAKNLDTGQTY-SYNGDERVRTASTIKVAVMIEVFARVA +EGHAKWTDELVLTKAARYAGSGILPEMSDGLLSLQDCVRLMMLLSDNTATNMVLDYL-GT +DAVNERMNSLGFKSTRIMRRVGGGGESKEGKLPDATTPREMVEILEKLARGQIVNETASK +EMIDLMKREQA-HYAIGRTIP-ETTVATKYGALD-ALRSCLGIVYSKQGK-IAMAITVDE +M---------------------- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0011D29818 +--SHAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIDGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAA-------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=2 Tax=Actinobacteria TaxID=1760 RepID=A0A329QFQ1_9ACTN +--ALQRDIGTLATSAPGRWGFAIRE--QGRAVaSINGATAMPAASTIKVALLIMALQEVA +AGRCELDRSLPVP-ERRVGGTGVLRLMPSVGLRLDETLELMIGVSDNTASNMVLDML-GL +DDVTGRINALGARNTRLERHMMDFEAS-RSGRDNTTTADDQALLLDLLTGPDLLPDHLRQ +LALDILGRQQF-NDRIPAGLGPDVGCRHKTGELA-GVRHDVGILDFDGR-SVAFAALGSE +LRTGTGPAADVIARAARAVVD-- +>[subseq from] Uncharacterized protein n=1 Tax=marine metagenome TaxID=408172 RepID=A0A382F6F4_9ZZZZ +---------------QHEIGVAYLNLDSGDTF-FHNEKTVFHAASTMKTPVMFQIYRMRD +AGQLSLEDSLPVINESIVDGSNYSMGNINNKMAVRHLIEAMITTSSNLATNILIELA-DP +EAVMATLKETGADGVSVIRGVEDLKA-FDQGLSNRTDAYGMMMAMKAVFDSQFVSVKSRQ +EMIGILKSQQF-NEMIPAGLPAGTSVAHKTGRIT-GITHDAAIVMHENDSPFVLVILTRG +WA-DYTLATGAGIEITKAVFQY- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus laterosporus TaxID=1465 RepID=A0A502IL83_BRELA +--TLGSQMLEVTEKAGGEWAIYIEDLSTNESF-MHQEKQPFYAASLIKVPIMSTVFQAVH +EGCFSFEDTITLRAEDLVGGAGVLQHLTPGTITICDLVMLMIIQSDNSATNILIDLV-GE +ENIRSMLHNTNMSNSLFYNKLMVIPAKLEG--TNTITAEDMAKHFRLLATGKIISYDASL +KMLSILKKQQV-RDAIPYTFPDPWELANKTGSVTD-LQHDVGILYVGQHA-ILLAFLSRG +LD--NNSARQTIAKLGKMVFDQy +>[subseq from] Beta-lactamase class A n=1 Tax=Aneurinibacillus migulanus TaxID=47500 RepID=A0A0D1Y2E2_ANEMI +-kQLDAYISRLIEETCGTWGIVIEDLDEDKRW-EWNTQESFLAESIIKVPVMAAAFAAVE +KKQFHLHDYVCLKKEDMVGGTGVLQHLTPGVLTIYDLITLMIIQSDNTATNIVIDLV-GM +ECIQETLEELGMEKSQFHRKMMIYPVH--IESKNVITADDASTLLKKLATGTFRSRHACE +QMIQILKKQQI-CNGLSSMLPPGWEFASKSGWDDD-RQHDIGILYTGQR-TFTISALSKG +GN--SLQAKQALGKIGLVVFE-- +>[subseq from] Serine hydrolase n=2 Tax=Bacteroidetes/Chlorobi group TaxID=68336 RepID=A0A350PBD4_9BACT +---LQVKILNRLVGIEGDFAIAYKDINDAEKHiLINADERFHAASTMKTPVLIELYKRAE +NTDLNLEDSILIKNESIVDGSLFTYLNLNKNTTFYALAYEMITRSSNLATNILIDYL-GA +ENITNTMRDLGADSINVLRGVEDLKA-YRQGLSNSTTARDLLVIFDHLSTGTLISKKANV +EMLKILKDQVY-NDMISAKLPKGTPVAHKTGWITN-VHHDSGIVFTGNDEGYILVFLSKN +AP-DRDAVLEASADISRMIYDSy +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium 13_2_20CM_70_9 TaxID=1805207 RepID=A0A1Q6WKG4_9BACT +------QLRARIARAAQAVGLYYRSLARPDSV-LIGANLRFHAASTMKVPVMIQIFRDAD +AGLLTLDDSLVVHATSLVDGSPFDYLRLGGKASVRELLELMITRSSNLATDILIERV-RA +PRAQASARALGAWSIQVLRGVEDGK-AYRAGLNNTTTARDLGALLAAIAQHRAASPAACA +AMLAILSRQEF-NEGIPAGLPPGIPVAHKTGWIGQVVYHDAALVSPPAGGGYVLVVLTGG +LQED-SVAYGLVRDLSHLVYA-- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophaga caeni TaxID=2029983 RepID=A0A291QW43_9BACT +-kALTKELSQIIKDFRGQVGIYVEHLGNGKTV-AINADSIFPTASMIKVPIMIGVFNKID +RDSLQYHQDLIYKDSLLYPGEDILGSFKEGAIQLSKVMMLMLTMSDNTASLWLQSLAGGG +SRINTWLEEHGYKITRVNSRTPGRAANQALYGWGQTSPSEMADLMKRIYKGELINPVTSE +RMYRNLTRNFW-DTEGLAMVPKNIRTASKNGAVNE-SRSEVIMVNAPSGD-YVYCICTKN +NIDQDNEAKQLLRKVALAIWKHf +>[subseq from] Beta-lactamase class A n=1 Tax=Tepidanaerobacter syntrophicus TaxID=224999 RepID=A0A0U9HQ47_9THEO +-----ETVQDLIKDVDGVCSVVIDSTWSDEKI-FINEDKIMSSASIIKLWILWKLYAESE +RRDIDLKKKIPLKDENKTTGAGVLQYMNSGLLSLHDYATLMITLSDNTATNILIDYL-GM +ESINQEIKKLGMPNTCLQRKMMDMKAR-SCGKDNLTSAKDIYDFFVKLLKGHDISAQSRN +EMIDMLLCQQF-NDRLSLYLPEDIQFAHKTGGLF-GIEHDAGIFFINDTK-VIIVVMMSN +LKN-NADGLKVHNALGAAVYNYf +>[subseq from] serine hydrolase n=1 Tax=Chitinophaga TaxID=79328 RepID=UPI000DBA2098 +-hKLEKGLKDLITGFHGDVGIYVKNLRTGRYA-AINADTIFPTASIVKIPILVGVFDKIE +KGELKYHQPLIYRDSIKYGGSGLMQFFKDSTTELSVLLALMMSYSDNTASIWNQSLAGGG +QRINELMEQYELAVTRVNSRTPGRAEIWKVYGWGMTTPREMATLLVKIRNGEVISKAASE +RMYRLMTHGYY-DETGLSAIPPYVQAAHKTGSLD-ASRSEVILVNEPRGE-YVFYVGTKN +NKTDDNEAQVLIKHVAAYLWKYf +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium 13_2_20CM_54_12 TaxID=1805419 RepID=A0A1Q6VME2_9BACT +-----------------ATAVSVHDLESGLRF-SLRGDRWFHAASTIKVGVLLALFRAVD +EGRVRLDDSLHVRNHFFSAGSAFQYQAIGRTAKIAALAAGMITASSNLATNLLLDFL-GV +AYARNVLRDAQVQGVELRRGVED-HAAHEKSINNEATADGLVALLSAL-RGDFLRSESKE +QAIRILLEQRF-NSMIPAGLPPHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EREGRRETVAAISEAIYH-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces mutomycini TaxID=284036 RepID=UPI0009A04DCF +---------------------------PSARV-TIDPDERLPMGSVYKVPLMVAFCRLVD +AGLIDPGRRLTLAPDDRVPPTGISILHDPVTMSLRDLVVLMMTISDNTAADAVLRVV-GP +DVVDAMCRDLGMPDTHIHGGVVTTFSVYDPAFKASTTPADMARLLRAIWTGQAASDERCA +FMRDVMRRQPW-THRLASGFPDDVTVYGKTGSFGS-MRHEAGVVELADGSTYTAAVFTQA +ARAKLPRADAVIGAAARTAVE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID5785 TaxID=2690309 RepID=UPI001360F39B +-gDVRRALRELFADAGVSGLVHVADVRRPEAAvTLGPDERVPIASVYKVPLMAAFWRQVD +AGVLDPRRAVTLDPSQRVAPTGISVLADPVTMSLRDLVVLMMTVSDNTAADAVLRAV-GP +AAVAQTCRALGLPDTHVHGGVAHTWDVYDPAHTSSSTPADIARLLHAIWTDRAASPAHCA +FMREVMSRQPW-RHRLASGFPDDVRVSGKTGTLG-ALRHEAGVVELPDGSTYTAVVFTRA +ARADLPRADAAIGTAARTAIE-- +>[subseq from] Uncharacterized protein n=1 Tax=marine metagenome TaxID=408172 RepID=A0A381NF87_9ZZZZ +-kQLETTLKDKITTFDGVAGLSVKSLTSGKSI-SINGDEVFPTASTIKIHVLAKLFSLQE +EGEIDLSQRIRFTQNMYGSGSGVIHFLENDPFTILDVAILMMLASDNTATNTCIDVA-GM +EGINDLIRDMGLSKTKLRRKMMDPE-AINRGDENVSTPNELILMMDLLHNEKP-TPKVSA +QVLRIMSKPKS--AYLNKAVGSKVVVANKPGGMDK-VRGDTGIVYLPNN-PYAVSIMSKF +SMVDSIAQEGFLIDLARNI---- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus sp. 17-4 TaxID=2486001 RepID=UPI000F780B50 +--------------LAGNTSAYVSRTDSDEEV--VRNNREQRAASDIKIFIMITAYEQAK +NNQLDLDGKYELSDDDKVGGTGVVQSMPAGTLTLRECIQYMIDESDNTAANIMIDAVGGL +DAVNDEISQLGLTDTQLERKLMDTD-ALNAGRDNMTSAKDLGVVLKQMYNHQLVSSGYDT +EMLNILAKNKN-HSKLLADLPAGAKGYNKTGEFSYGVQNDAAILESSKA-ALVVVVLSED +GQESTQ----------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium sp. JUb20 TaxID=2485110 RepID=A0A4R3A6K8_9SPHI +-kKLDRQLRALTQDFHGDIGIYVKNLKTQKEV-LIQADSIFPTASIVKVPILAGIFDKIE +KGELALDQKFTYRSSQQYGGSGLMQFFKDSSTDLATMIGLMISYSDNVTSIWNQQLAGGG +STINQLMDQLGLVNTKVNSRTEGRNEIWKKYGWGQTTPREMATLVALIFQGNVVSTKASD +KMYRYLGNIFY-NERSLSQIPAYVKTASKTGSVDE-ARGEVVLVNAPSGD-YVFCVLTNN +IKTKNNEAEELTRKISHLLWNYf +>[subseq from] serine hydrolase n=1 Tax=Aminobacterium mobile TaxID=81467 RepID=UPI0012EC2EC9 +------------ESFKGTAGVVIKDVQGKVKM-SVNGGEVFPSASLIKLPVLWTLFMEAH +SGKLSLDDTLVLKNEDKVDGGILHKYREGALLRLEDLALLMISVSDNTAANLVIDRL-GK +DRINNEIKDLGLHKTILGRKMLDFEAK-KEGKDNYTTPEDMASLLEIMLTSPKLPASLRE +RMLELMTLQKL-NSKLPSLIPIEGFLAHKTGELP-GSEHDAGIFFHGTETPVIVTILTKD +LS-SRMMGVELCSKIGLIIFEHf +>[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium sp. IITKGP-BTPF85 TaxID=1338009 RepID=A0A0M3CAH2_9SPHI +-kKLDRQLRALTQDFRGDIGIYVKNLNTQKEV-LIEADSIFPTASIVKVPILAGIFDKIE +KGELTLDQKFTYRSSQQYGGSGLMQFFKDSSTDLATMIGLMISYSDNVTSIWNQQLAGGG +STINQLMDQLGLVNTKVNSRTEGRNEIWKKYGWGQTTPREMATLVALIFQGKVVSTKASD +KMYRYLGNIFY-NERSLSQIPAYVKTASKTGSVDE-ARGEVVLVNAPSGD-YVFCVLTNN +IKTKNNEAEELTRKISHLLWNYf +>[subseq from] Uncharacterized protein n=2 Tax=Halobacillus sp. BBL2006 TaxID=1543706 RepID=A0A0B0D4U6_9BACI +--SFKAEVEHTAASIKGNVSIVVKT--TDETI-EINSKKKVPAASTIKIPILMEAFRQVE +IGELDFDEKVDIPSHKKVGGDGVLKLLNNSLLSILDLMKLMIVVSDNTASNLVIDRL-GF +SNINNLCEKLDCTDTRLNRYFMDFE-AIKAGVDNATSASDMVQFFSEIKESQLLSRKSCQ +SIYNILKEQQF-ASGLPAYQKGDLEIANKPGMLP-GVQHDVGIFTYNSET-VYAAVLLSE +LD-DEEAGRRVIADMGRSIME-- +>[subseq from] Uncharacterized protein n=1 Tax=Pseudomonas sp. PIC25 TaxID=1958773 RepID=A0A2A2DSE8_9PSED +-eQLQGKILRLDQRTPGDLGVYIKHLGDDGEL-DHQAGRYWYLASAVKVPVAIATLQRVD +EGVWPLNQRLALRNEDKVDGSGLAWQDPGSEYDLKTLLEEMLQRSDSTAADMLINRI-GE +DELNRRIASMADQGTSLLRVRHELYRRYYARRLNAATLRAYGGMLEKLARGHLLSRANTD +LLLDLMGLDEYHAYRLEAGLGKDVPFAQKTGTQFE-RACHMGIIDPKSEQPIVIAACVEG +AGQ--EQAAQTLETLGSLV---- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6FIM6_9BACT +--TFNEEVERLSAGSKARIAVAVHDFQSGLRF-SLRGDRWFHAASTIKVAVLLAIFRAGD +EGRVHLDDSLHVRNRFISAGSPFHYQLVGRTAKISTLAEGMIAASSNLATNLLLDFM-GV +EYARKVLRDAQVDGVELRRGVEDYA-AHERGINNEVTADGLVSLLSAV-RGDFLRNESKE +QAIRILLEQRF-NSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +DS-EGNGRREIVAAISVAIYR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) TaxID=405948 RepID=A0A2A9J997_SACEN +--RLREALEPGWADFPGRVGFAAWDLDEREPV-LFGARRVVHPASTIKVLVMLTALREVQ +RGGLALDTEVRFP-DERVGGAGVLKDLPGLRLELADAITLMISISDNTATNAVIEAV-GF +EAVGELAAELGCEGTQVQRLLMRVQDP----GRNTTCALDQARILDSLARGTVLPPRLTQ +HALWVLSRQQV-RDRLPALLPEGARCWNKTGEID-GSRHDVALIGDHERPRAVVAVLVDE +LA-DHRAGAARIAGLGLSVYE-- +>[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides uniformis TaxID=820 RepID=UPI00125D4DBF +------------------------------TV-TVNNKSIYPMMSVFKVHQALALCNDFD +KKGSSLDTLVKINREKLDPWSPMMKDYSTPVLTVRDLLRYTLIQSDNNASNLMFKSMLNT +AQTDSFIAKIPRSSFQIAYTEEEMLADHDKAYSNYTSPLGAAVLMNRLFTESLISDDKQS +FIKNTLMECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAFIRLPHNKYYTLAVFVKD +FKGNETQAAKIIARISNTVYS-- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6G8I9_9BACT +-----------------------------------NADRVFPTASSIKIAVLVELYRQDQ +KGKARLDDTYTFDPKDLVEDSRIMAGLTAGVVTNRDLAQFMVAVSDNAAANILIDRV-GK +DNVNATLRAVGLSKTMLRRKMIDIAAARRG-DENVATPEEMVRLLEVIYKGKVLNNEATA +ALTKQLSTLKQ--SYIPRLLPENVQVANKPGELE-AVRTDSGIVFATNR-PFAICVMTAY +DR-DERAAERAISEVALEAYRYf +>[subseq from] alpha/beta hydrolase fold domain-containing protein n=1 Tax=Prevotella copri TaxID=165179 RepID=UPI00142EE1FA +-------------------------------YcGHQEDSAFAMHSVMKFPQALYVADYLH +KKGLTLSDSVLVHKDSLDAWSPMLSIFEGMRFTFAELIEWSLKQSDNNACDLLFASCGQP +DAVEKYIHTLGFKDIHVQLTEKEMKKNPHRTIENSATPKEMARLLEWFYLHRD-DNKNLS +FIWDTMADCNTGQQRIAAVLPKDGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFLQK +SKEEKEVAEI------------- +>[subseq from] Serine hydrolase n=1 Tax=Desertiactinospora gelatinilytica TaxID=2666298 RepID=A0A2W2HKS7_9ACTN +------------RAAGVTGWLHAADIDTGAQV-GFGAHAAVPTASVFKLPLLVAFVRQAD +AGLLDPAERVAVPAADRVFPTGISAMLDDVTASLRDLCYLMIAVSDNTAADVLLSRV-GI +DAVNAMLDDLGLTATRVLHDCREMAAVLDPAGTNRSTPAELTRLLGMVWRDEAASAASCA +FVRRLLGLQVW-PHRLSSGFPDDVSVSGKTGTLPT-LRAEAGVVEYPDGGRYAVAVFTRS +HALNQPRADAVIGTAARMAIDH- +>[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000996D80D +------------------------------------------------------------ +------------------------------------------------------------ +---TDYLRELGDTVSRLDHYEPELHQVRPGDPADTTTPRAIAADYRTVILGDTLARDQRA +LLTDLLERNKTGGNRIRAGVPKGWRVADKTGTGQYGRANDIAIVWPPGSRPLVLAIMSER +SGREARPSEPLIAEATEHVT--- +>[subseq from] Uncharacterized protein n=1 Tax=Nocardia asteroides NBRC 15531 TaxID=1110697 RepID=U5E5Y0_NOCAS +--------------------LHARRCDSAAEV-SLGGDDRVVVASVYKLLLLAAFCRRVD +DGRLDPAARITVVPADCTPPTGLAALHDPVTLSFRDLATSMMTVSDNAAADVLLGEV-GL +GAVGDLVDELGLTGTRIVGGTADQHRAYDPSYASATTPEEMTRFLRLLWSGAVLSTASTE +FVRSVMGRQVW-QHRIAAAFPSGVLVAGKTGTIGV-IRNEVAVVEFPGETPVAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Beta-lactamase n=1 Tax=Niabella soli DSM 19437 TaxID=929713 RepID=W0EV13_9BACT +-kKLKALIESAISGFHGDVGVYVHHLKKNKSV-AINADTIFPTASIVKVPLLAGVFQKIA +KGDLKLSQEFVYNAKRAYGGSGLMQFYKDSATDLSTMISLMLTYSDNVAAIWLQELAGGG +ATVNPLMDQLGLPHTKVNSRTAGREDIWKKYGWGQTTPKEMAQLFTLIRQGKVIDARYSD +KMYRYLKNQFY-NGRSLSQLPATVSTICKTGSIDD-ARGEVVLVNAPGGD-FVFCILTKN +NKTDNNEAEVLTRKLASIIWNHf +>[subseq from] Beta-lactamase n=1 Tax=Deinococcus grandis TaxID=57498 RepID=A0A100HLC2_9DEIO +-----------ASGFPGVVGLRVTDLNGTELV-AWNADRVFPAASTIKVPLLVLALQEAQ +AGRLDLSARVTMQPGDRVPGAGVLHDLDGGLLTWRDVLTLMIVVSDNTATNLVIGRL-GV +DAVNAWLAAQGLTGTRLVGKLEQRNEAQRRGERNATTARDQTALLRALVAGEVLVGTHTA +LALDILERQQY-RDLIARHVPCGYRSATKSGELL-GVHHDVGVLFTP--RPLLVALLSGG +GADPR------------------ +>[subseq from] Beta-lactamase class A n=1 Tax=Stigmatella aurantiaca TaxID=41 RepID=A0A1H7YNA0_STIAU +---LNGLVETAARDFDGELSLYVLDVASGEEY-AYDAERPTYLSSAIKLGVMLEVMHQVD +AGRLSWDEPLTFTPDALRDMHRLHRAQPGDALPVSTLLEYMMVDSDNAAADLLIARV-GV +DAVKAQLAARGVQTGPVVSLLDERRRAFYAEQVNSAPMRQMGQLLRQVARCEGLSAASCT +RAHTLMRACQTGSARIAAGLPATAAWAHKTGTQHR-RACDMGFLTLPSGQPAVIAACTRN +FWR-VADAERLFALLGESVWR-- +>[subseq from] Uncharacterized protein n=2 Tax=Chloroflexi TaxID=200795 RepID=A0A357FLV1_9CHLR +-kQLETTLKDKITTFDGVAGLSVKSLTSGKSI-SINGDEVFPTASTIKIHVLAKLFSLQE +EGEIDLSQRIRFTQNMYGAGSGVIHFLENDPFTILDVAILMMLASDNTATNTCIDVA-GM +EGINDLIRDMGLSKTKLRRKMMDPE-AINRGDENVSTPNELILMMDLLHNEKP-TPKVSA +QVLRIMSKPKS--AYLNKAVGSKVVVANKPGGMDK-VRGDTGIVYLPNN-PYAVSIMSKF +SMVDSIAQEGFLIDLARNI---- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=2 Tax=Planctomycetes bacterium Pla144 TaxID=2528003 RepID=A0A5C6CH84_9BACT +---IAQRLQELAGSVPGKIGYQIARVDGEVLY-SQLSDEVFPQASAIKVPLLMEVLAQRE +EAKIDWNAAHPILKKHQAGGSGVLFEFSDGCICTQDLCTLMIVLSDNTATNMLIELV-GM +ASVNQRMESLGLTQTRLQRVMMDMDAR-ARGEENVSTPREACQIMCLLAQGKFINQEISD +ELLGILRKPKS--TAIRNGIPAEIAVATKPGAIP-GVATEWALIEYPKQ-PYVAVFMGKE +G--SEKEFNEVFTEMTRCIH--- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7VBL1_9BACT +----------------ERLGIAFYDAETTLQW-SYNADLAFHAASTMKLAVLLAVFRQYT +RGKFSIYDRKPYMLDINRDTEGEIYDHLGRTMSVKQLAYYMITCSSNFATNLLVDVV-GV +PVIQTALDELKIDGIRVLRGVEDH-GAFEAGLNNEVTANGLLKLLRLVAEGKAYGEEASA +QMREILLDQRY-KSGIPAGLPQAARVAHKTGNIST-VHHDAGIVYLEGRKPYVLVILTQF +SSE--TGRTTAVADVSRDIYE-- +>[subseq from] Uncharacterized protein n=1 Tax=Coriobacteriia bacterium TaxID=2052159 RepID=A0A316RU59_9ACTN +---TEAAVARIISGHGDNVAVSVRMLDGSGSI-DINGDEPMQSASMIKLLVLAEYLDEVD +SGELLADETYTLDGGDIVGGSGTMQDDPGSEYTLDEVAHRMVAVSDNVGTNVLIGRM-GV +EAIQQKATELGLDGTNLAHKLMLPAN---DGSFNMISANDACRILERVASGTLASKGSCE +RAEDFLLDQED-DEGLAQGLPADVAFGHKTGTVD-GIRHDGGIVYAE--HPYVICVLTRG +LD--YGVANALMAQVSAAVYR-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus infantis TaxID=324767 RepID=UPI00101C2175 +-nQLEKRLADILRQCPGNASLAVEY--GERAI-YMNSGRKYPAASLIKIPIMMEAFFQAE +EGVLDLSEQVRIGGIEKAGGAGIIQSLSVTALSILDCITLMIIVSDNTAANLLIKLL-GK +KNINDRMHGLGLQTTVLGRKMMDFEAA-AKGIDNFTTAADMVKCLRAIKDGELFSEKNRS +KMLDIMEAQQF-REKLPALACKELKIANKTGELP-GIEHDCAIFAS-GRDVLYAAVLIEG +LS-SPEEGNHAIRLIG------- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus kimchiensis TaxID=993692 RepID=A0A0R2LNF7_9LACO +--------ADNLGSLAGTNGAYYYNLNDHVSS-GMSENTKIRAASDIKLFIMAVAFQKID +DGDLSLSDRYTLTDDDKVGGTGIVQSMQSGTLTYKDLINYMITQSDNTAANIITDKVGGL +SAVNEEITKLDLNHTDMQRKLMDQD-ALDEGRDNYSTAKDLGTFLTKLYQHNVVSKKYDN +QMLDIMANDSN-HTKLPSRINTDVTVYNKTGEYDYGVQNDAAIFKRGKK-AFVIVVMSEN +GKTD--DQKDAMGDLGAALA--- +>[subseq from] alpha/beta hydrolase fold domain-containing protein n=1 Tax=unclassified Prevotella TaxID=2638335 RepID=UPI000B979AA6 +--------------------------MNGDLYcGHQEDSVFAMHSVMKFPQALYVADYLH +KKGLTLSDSVLVHKDSLDAWSPMLSKFEGARFTFAELIEWSLQQSDNNACDLLFASCGQP +DAVEKYIHTLGFKDIHVRLTEKEMKKNPHRAIENSATSKEMTRLLEWFYLHRN-DNKNLS +FIWNTMADCNTGKQRIAAILPKDGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFLQK +SKEEKEVAEI------------- +>[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2S1FJE0_KLEPN +------------------------------------------------------------ +------------------------------------------------------------ +--MTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR +QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD +TPASMAERNQQIAGIGAALIEHw +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Bathyarchaeota archaeon RBG_13_52_12 TaxID=1797379 RepID=A0A1F5DJW6_9ARCH +-sKLRRRLEEALERYEGVIGAAVKDLTTGESL-FINEDEVFPVASTIKVPILIEFHRRVE +AKTLDPMTPVDFVEAHRTGGSGVLKTLTPGAMPLIDYVTLMINVSDNSSTNYLIDLL-DL +SKINALIAELGLRETRLARKMMNMEA-FKAGKDSFTTPRELVAMFEELYTPRALSQFVCG +ETLKMLKKPKEGQGVIRNAIPDSVDVADKSGWVG-GATLDAGIVYQPSR-PYAVALLAKH +IPSSMVNALNTLTEMARLIQ--- +>[subseq from] hypothetical protein n=1 Tax=Geobacillus sp. (strain Y412MC10) TaxID=481743 RepID=UPI0011A5ED20 +-----------AEKDGIRMSVGIRDLSGHETL-LLGSQEPYMPASTIKLAVVSALMQQVD +RGELSLADQVRVTPGDVVGGSGSLQTSFPQDLTLERLARLMITQSDNTATNVLIDKV-GM +DRVQQLMDQLDLRTMHLGRKMFAA--APSPTQDNYIDAADLTELLGQIYQGSFLSVSSRN +QIIAWMARQEV-NTKFGAALS-DAPIAHKTGENAN-VTHDAGYFLVPGHE-LAVSVLLQV +TTEAQRIGNPIVQKAARAIYS-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=UPI001318A71E +---LREEMMGIVQECSGKVSFSVLL--DDESL-SWEEDRRISSASLIKLPILMAAYEQIQ +TGRLRADAMIVLRHEDHVEGAGVLNGHDGLTLSIEDLLTLMITVSDNTATNRLIELI-GM +DSINRFCLDWNLKGTFLNRKMMDFPS-LEMGKDNWTSSEDVVSCLTLINEGPF-EEASRK +KMLTMLSRQQF-RDKLPALLGDDVKVFNKTGELP-GVEHDCAIIESASGKYAYVAVLTDE +LPAP-EEGRRVIRTMGKLIGD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. AmelKG-E11A TaxID=1100822 RepID=A0A1C6LMD3_9ACTN +----RSRIRSVFTDAGVTGWMHALDLGDGAEV-AVAADTPVSTASVHKLCLAVTVQRFAD +EGRLDLDEQLESLPGDRTPGPTGLSMLSGPVMSVRDLLAMALTVSDNAAADLLIDRV-GL +DAVNDAMRALGLRRTVAVQTMRDLIAVLDPARANRSTPREMTRLLAALWRDEACSAERAR +ELRAVLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-VRNEAGVVEYPDGGRYAVAVFTRS +ARARQPAADAAIGTAARLAVR-- +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. OD32 TaxID=2136176 RepID=A0A2T3W7B5_9DEIO +-------------GFPGRVGLRVCALDGTELV-ATGADEVFPAASTIKVPLLVMALQAAQ +TGRLPLHGRVTMTAEDRAGGAGVLHELAPGLLTWQDVLTLMIVVSDNTATNMVIEAL-GL +EAVNDWLAAHGLGGTRLVRPPHLQNEAQRRGERNATTARDQTEVLRALVAGEWLDPTHTA +LALSILERQQY-RDLIGRRLPRDFRVASKSGELL-GVRHDVGVLWTP--RPLLVALLSRD +GGREHPENRDVLALAAA------ +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0011D1DFE7 +--SHAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKESGGI +KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPA--------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=2 Tax=Bacteroidetes/Chlorobi group TaxID=68336 RepID=A0A3D4UV06_9BACT +----QVKILNRLVGIEGDFAISYKDINDAEKHiLINADERFHAASTMKTPVLIELYKRAE +NTDLNLEDSILIKNESIVDGSLFTYLNLNKNTTFYALAYEMITRSSNLATNILIDYL-GA +ENITNTMRDLGADSINVLRGVEDLKA-YRQGLSNSTTARDLLVIFDHLSTGTLISEKANV +EMLKILKDQVY-NDMISAKLPKGTPVAHKTGWITN-VHHDSGIVFTGNNEGYILVFLSKN +AP-DRDAVLEASADISRMIYDSy +>[subseq from] Beta-lactamase n=1 Tax=Synergistetes bacterium ADurb.BinA166 TaxID=1852916 RepID=A0A1V5I7Y3_9BACT +-------IKKRAEEFSGTAGLVVHSLADGERL-AHNWDRVFFSASLIKLGILNTLFLNAA +RGELSLDEKIKLEEGMAVDGGLLHKMRPGVSWRLDDLALLMIALSDNTATNMLIDRL-GI +EEINRDFKRLGLENTVLGRKMLDFEAK-KAGRDNFTTAADTACILQTLHSGEELPPGYRA +RAMDILSAQKL-NNKLPGLIPVDQILAHKTGELP-GIEHDAGIFFFKSKMPVVAVVLTEG +HD--RQEAVELCARVGKTVYEAf +>[subseq from] Beta-lactamase domain-containing protein n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5K7XXQ7_KLEPN +------------------------------------------------------------ +------------------------------------------------------------ +------MHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Beta-lactamase class A-like protein n=1 Tax=Bacillus sp. LF1 TaxID=1499688 RepID=A0A0U1NQ97_9BACI +---LKYNMEEELHGFNGRVGLAIEI--EGESF-YFNSEKIFPSASVIKIPILIEGLRQSE +IGKINLEELISIPN--RAGGSGVLQILSSNVMTVKDLMTLMIIVSDNTATNLLIDLL-GI +EAINGSMKNMGLQDTVLSRKMMDFE-AIEHGLDNYTSPRDMISCLKVVNEGTYLSEASRK +IALEIMKYQQF-QDKLPGMIDDRMFVANKTGSFPR-VEHDCAIFKYKGRT-AYAAVLLDN +LD-DIFVGKQKISRIGKHIYNY- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus grandis TaxID=57498 RepID=UPI0009FB3A82 +-----------ASGFPGVVGLRVTDLNGTELV-AWNADRVFPAASTIKVPLLVLALQEAQ +AGRLDLSARVTMQPGDRVPGAGVLHDLDGGLLTWRDVLTLMIVVSDNTATNLVIGRL-GV +DAVNAWLAAQGLTGTRLVGKLEQRNEAQRRGERNATTARDQTALLRALVAGEVLVGTHTA +LALDILERQQY-RDLIARHVPCGYRSATKSGELL-GVHHDVGVLFTP--RPLLVALLSGG +GADPR------------------ +>[subseq from] serine hydrolase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI0012615666 +------------------------------------------------------------ +-----------------------------------------------------LEKIGGP +AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ +QLKTWMQDNKVADGLLRSVLPQGFQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ +TEATFNERNTAIVAIGKSIFDTf +>[subseq from] Beta-lactamase class A n=1 Tax=Gemmobacter megaterium TaxID=1086013 RepID=A0A1N7KLQ9_9RHOB +-------------AGGARIGLVLSR--DGTVLfGHRAQERFLSASVVKIAIMVEIYRAAD +AGRLRLEAPVTVTAPMMAKGSGVMNRLVPGYVQVQDLLYLMMAISDNTATNLLIERA-GM +AAVNATMADLGMAGSNLGRPMLGRP-ATADEIENIAVPMDYDRLMQAILDGRAASQGACA +AMLDLLRAQQN-ERRLARHLPAGADWGSKTGTLD-GVVNDAGFLRTADGT-ACLSMFTQD +F-ARMVDAEEVLGDMAQAAF--- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Paenibacillus TaxID=185978 RepID=A0A1R0WHV5_9BACL +---------------GVRVTVSVADLSGNLGF-SIGSEERYRSASTIKLAIACALLQMVD +RGEVRLEDQAVVRDKDVVGGSGSLQLEVMPLINIGRLAKLMIAQSDNTATNVLIDMI-GF +ERVRAMLEGLGIHQTQLARKMFAPVQS--PELDNYADARELTYLLKLVYQGEVLSEYSRR +LLLLWMSRQEV-NTKFGAVLG-DMLIAHKTGEASN-VTHDAGYFLIPGRE-LAVAVMTEV +MTEAQRIGNPVIQRIAKIIYDQ- +>[subseq from] serine hydrolase n=1 Tax=Microbispora sp. GMKU363 TaxID=718014 RepID=UPI0006E22B7A +-------IEQVFRSAGVTGWLHATDIDTGHEV-GLGADEPVVLASVFKVPLLIELYRQAE +RGTLDLTEAVRVPASSRTSGTGLTAMLDDAELSLRDLAYLMIAVSDNAAADVLLARV-GR +DSVNAFLAGLGLNGTRVAHDCREMFAVLVPALTSHGTPRELTRLLGMIWRDEAAAPASCA +AVRRLMGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-LRNEIGVVEYPDGGRYAVAVFTCS +FSQNQPKADAAIGSAARIAIDH- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium RIFCSPLOWO2_12_FULL_67_14b TaxID=1797193 RepID=A0A1F2VNY3_9BACT +--TLHAVLARAATEFPGRAGIWVKHLTTGETA-GVRDGEMFNSASVIKIPVLVLALQMAD +RGEINLDERLTIRKEDIRGGSGIFRHHDAGLPTLRDVLLQMIITSDNTATDLSIAKVGGV +ARVNAWLKETGYDGQRLVQTTGELFAKTNGDRSGELSPKSIGLMLEAIEKKTIASAAGCD +AMLRMLRAQQAGQRRLNHYVT--VPVAHKTGDFPPVLANDVGIIYARSG-PIVVSFLGNA +ITGNYGEAEDRIGRVAQQIVEYf +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. 22-7 TaxID=2709707 RepID=UPI0013D8BB9E +-hTLKAEILTLASCCEGRVAVYIHT-E-DGFI-EKDADAIFSSASLIKVPILLAGLLQAE +KGLLQLEEEVEVTVSARVGGSGVLQAMARDLIKVTDLMTLMVIVSDNTATNLIIELL-GI +EKINQLFKDLGFNNTSLNRKMMDFE-ALKNGIDNTTTARDMVYGIKALAEQKLLSGKYTE +KALYILENQQFKNKLANTIDEEKVMVANKTGELP-GIEHDCAIFTHKGK-TVCAAVLVDR +LL-NQTAGKEVLSAIGSRI---- +>[subseq from] serine hydrolase n=1 Tax=Nocardia harenae TaxID=358707 RepID=UPI0009FE62DE +---AAHRIRAVFADAGCTGWLHARRCDSADEI-TVRGTERVVTASVYKLPLVLAFCRAVD +EGRIDPAARLTVDPAECTTPTGLAALHDPVTLSRRDLATSMMTVSDNAAADVLLGEL-GI +GALHALLDELGLTATRIVGGTADLHRAYDPAFTSATTPEETTRLLRAVWAGAVLSPGQTA +FVQSVMRKQVW-PHRIAAAFPRGVAVAGKTGTIGT-IRNEAAVVEFPGEHPVAVAVFTRA +ARAELPAVDAAIAEAARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535AF53_9CHLR +--------RALIERAPFRVGVFARSADAETLL-EHDPDQALPSASVIKVPLVMTLYADAA +DGRIDLERRMRLG--DRVDGSGVLRDLRDVAFSLRDLAALTMILSDNTATNLVIDAV-GV +ESVAERLAEWGCRKTALRRRMYDFEAA-KRGLENVATARELASLLAILVEGRCRDRSTSD +AVLAVMERCAD-DTMLRRFLAPGTMVPSKSGTLD-ASRNDVAVIRGPERT-VLVAAFTSH +VE-DHLAAEHLLGIIGRCA---- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A519L2G1_9CAUL +------------------------------------------------------------ +---------------------------------VEQLMKGTVEVSDNPAANLLLKAMGGL +EAMQAFYRGLGDTSTRVDRFEPEMNRL--DGDKDTINPSQSAANMQRLFIDPALSAVSKA +MLLGWMTTSPTGMDRLKGGVPAGWRVAHKTGTGGYGPTNDIGILYPPSGAPVIVAAYYHA +MPTTDAQNAAVIAAATRLAL--- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus agri TaxID=51101 RepID=UPI0002A4D10F +--DLEKSLSAILQEAKGAWGVVVKELANGAYF-AHRPDELFIAESVIKVPIMAAVYAACE +QGKARIDAQLALRKEDLVGGSGFLYALSPGLLSIRDLVTLMIIQSDNTATNMLIDLV-GK +EQIDRTMRELGMERSRYSRKLMIYPQD--VTENNMITAGDVARMLEQIACGGRFSRWASA +DMIAIMQKQQV-LHGLPSQLPSRWELACKSGWDT-GRQHDVGILSVQGR-QFAIAALSQD +VRA--EAALHTLGLLGRAVYD-- +>[subseq from] serine hydrolase n=1 Tax=Staphylospora marina TaxID=2490858 RepID=UPI000F5BAAC5 +---LFRKLDEWKSTLPGTWGLVVEDLQTGTRW-TVNEDRLFYAASLIKVPIMAAVYREEA +AGRLTLEEEWPLSLEDQVGGSGILQHLSPGILPIRDLVTLMIIQSDNTATNMLIRRV-GT +ETIRKTMVELGMRHSRFHNPLMIVP--YPLENVNVVTAADMAACFRRIARGEAVSLHASR +RMIRTLKKQQD-AAGLPSLLPPKWEWAHKTGQVNR-ILHDAGILYVGGRA-LSVTALSEG +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. T33-2 TaxID=2054168 RepID=A0A2N5GXT7_9BACI +-----------IKKCKGRASIKLVI--DNYIL-KVDSQEPFPSASLIKIPILIAAYRQKE +LGLLDHQRRITVAAGKTVGGAGVLQALSGNLYTIKDLLTLMIIVSDNSATNLLINEI-GM +ESINDCLVKLGLAKTSLNRHMMAFA-ALQQGRDNYTCADDVVECLMTINNGMFLSKDSRS +EMLNILQMQQF-KDKLPALMDPGVTTANKTGELP-GVQHDCAIIQCNDKT-AIVAVLTDQ +LR-SHEDGRQTIRKIGKLVFD-- +>[subseq from] Serine hydrolase n=1 Tax=Aminipila sp. JN-18 TaxID=2507160 RepID=A0A410PU21_9FIRM +------------EGMRGKVGFYYKNLVTDETV-GFHEDELFRAASIFKFPLFAAMVYEKE +HNHVDFSEKIKILESEKIPGCGAVQHMTGDPVDILTLGKLMITISDNTAANALARHF-GI +EKMKGVFEKLGMKKTRLNRCLYDFESE-NKGIMNVFTPKEMGELLEKIYKRTLISKEASE +FIEDILLKQQI-NSKIPAKLPYAFKVAHKTGEEEK-TTHDVGIVYAK--EPFIVCFASND +TD--------------------- +>[subseq from] serine hydrolase n=1 Tax=unclassified Sphingobacterium TaxID=2609468 RepID=UPI0013DA994C +-rTLEKKIKKEINGFQGDVGIYVQHLRTDKIV-SINADTVFPTASIVKVPILVGVFQKIA +QGELKLNQAFQYSDKRAYGGSGLMQFYKDSATDLSTMISLMLTYSDNVTSIWLQELSGGG +TAINPLMDQLGLPHTKVNSRTPGREKIWEEYGWGQTTPREMAKLFTLIRNGQVIDARHSD +KMYRYLKNQFY-NGRSLSQLPAWVSTIAKTGSVDQ-ARGEVVLVNAPSGD-YVFCILTKN +NKTDDNEAEELTRKLSNIIWNHf +>[subseq from] Uncharacterized protein n=2 Tax=Clostridiales TaxID=186802 RepID=E7GH40_CLOSY +---LKLNVLNLCSRIEGKKAIVIEDLKTGEAV-EINRDEVFPAASLIKVPVLSALFRMAK +ESQIALDERIELEKDSRIGGFGILKDLGDGLPSVRDLAVLMITLSDNIAANLLIDRI-GM +SQINSELQAMGMKHTVLQRKMMDSQAK-ERGLDNYTSAGDMQKLMKAILESSF-----RG +DILDILFRQQC-NNKLPALMEGDVRFAHKTGDLP-GVEHDAGIICTDDRE--IIAIVLTD +ELADNREGIWLNQEIGKLI---- +>[subseq from] Beta-lactamase n=2 Tax=Bacteroides pyogenes TaxID=310300 RepID=W4P3V4_9BACE +-------------------------IMNGDIYcGHQEDSAFAMHSVMKFPQALYVADYLH +KKGLTLSDSVLVHKDSLDAWSPMLSIFEGMRFTFAELIEWSLKQSDNNACDLLFASCGQP +DAVEKYIHTLGFKDIHVQLTEKEMKKNPHRAIENSATPKEMARLLEWFYLHRD-DNKNLS +FIWDTMADCNTGKQRIEAALPKDGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFFPK +SKEEKEVAEI------------- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WSA7_9BACT +------------------------------------------------------------ +-------------------------------LPLERLLELMLGESDNSASDLLLRLAGGP +AAVTNRMQALGIMGINVSRPEGQLILAFADDPRDTSTPDAMAQLLVRVERREVLEPASME +RLLQITTATQTGPLRLKGLLPAGTPVAHKTGTMG-ATTNDVGIITLPDGGHVALAVFVKG +STLDVPSRERVIAEIARTIYDYy +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus laterosporus TaxID=1465 RepID=A0A518V860_BRELA +--TLGSQMLEVTEKAGGEWAIYIEDLSTNESF-MHQEKQPFYAASLIKVPIMSTVFQAVH +EGCFSFEDTITLRAEDLVGGAGVLQHLTPGTITICDLVMLMIIQSDNSATNILIDLV-GE +ENIRSMLHNTNMSNSLFYNKLMVIPAKLEG--TNTITAEDMAKHFRLLATGKIISYDASL +KMLSILKKQQV-RDAIPYTFPDPWELANKTGNVTD-LQHDVGILYVGQHA-ILLAFLSRG +LD--NNSARQTIAKLGKMVFDQy +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A523DZI9_9BACT +-qTLEARLAAMLDALPAKSSLYAKHLPTGRVV-SVRGDELMNPLSVIKIPILALAFRDSE +AGKLDLAERYTIKPEDRRRGSGLIQTFAPGLPTYRDILTQMIVTSDNTATDIMIDRL-GL +ERVNELLSERGYRSTRLMTTTGGLFRGNPKEWLGQTTAKEMSKLLEEIYNAELTSHASSD +AMIGILRRQFY-RSRLPRFVRDGVGVAHKTGDWPPVAGNDVGILFHEGG-PTVVSVFINQ +NRGDFTKLEETIGQIAKELVAEw +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. NSP2.1 TaxID=1071072 RepID=UPI0003FF11D0 +--DLEKSLSAILQEAKGAWGVVVKELANGAYF-AHRPDELFIAESVIKVPIMAAVYAACE +QGKARIDAQLALRKEDLVAGSGFLYALSPGLLSIRDLVTLMIIQSDNTATNMLIDLV-GK +EQIDRTMRELGMERSRYSRKLMIYPQD--VTENNMITAGDVARMLEQIACGGRFSRWASA +DMIAIMQKQQV-LHGLPSQLPSRWELACKSGWDT-GRQHDVGILSVQGR-QFAIAALSQD +VRA--EAALHTLGLLGRAVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis acidiphila TaxID=715473 RepID=A0A558A8E6_9PSEU +---VEGRLREVFRDAGVRGWVHARPVTGDGEV-GFGADDPVVMASTYKVVVLAAFCRAVD +DGEIDPREPVTVHPDTRTEPAGLSALRDAVTMTWRDLATSMITVSDNAAADAVHRRL-GA +GRVQAVLDDLALTATTVRGGTDDVHRALDPVYGSATTPREMTRLMSALWRGDVASPEQTA +FARQVLLAQVW-THRLRAGFPGAVRVAGKTGTLG-AVRNEVGVVSYPDEHPVAVAVFTHA +ARAEVPRADAAIGTAAY------ +>[subseq from] serine hydrolase n=1 Tax=Sphingobacterium sp. xlx-73 TaxID=2654181 RepID=UPI0013DC1847 +-rTLEKKIEKEINGFQGDVGIYVQHLRTDKIV-SINADTVFPTASIVKVPILVGVFQKIA +QGELKLNQAFQYSDKRAYGGSGLMQFYKDSATDLSTMISLMLTYSDNVTSIWLQELSGGG +TAINPLMDQLGLPHTKVNSRTPGREKIWEEYGWGQTTPREMAKLFTLIRNGQVIDARHSD +KMYRYLKNQFY-NGRSLSQLPAWVSTIAKTGSVDQ-ARGEVVLVNAPSGD-YVFCILTKN +NKTDDNEAEELTRKLSNIIWNHf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces cyaneogriseus TaxID=68192 RepID=UPI00099B62B0 +--SIARRIGAAFAEAGVTGHLHAVDIDSGAEV-DAGADQPVVTASVHKLCLLVALHEQAE +AGRLDLAERVECPPDDRTSGPTGLAAMLDPVISLRDLAYLMMAVSDNGAADLLLRRV-GL +DAVNATTARLGLERTRALHTFRELFAALDPARTNHTTPRDMTRLLGAVWRDEACLPGHCA +AMRRILGLQVW-PHRLASGFPDDVRVSGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRS +ASATLPAADAVIGTAARMAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudonocardia cypriaca TaxID=882449 RepID=A0A543GFE0_9PSEU +------------AGVQGRLHAAPID-GPTREV-GVDPDEPAVMASVYKLPLLVAFCRRVD +AGEIDPRERVTVHPAEHTAPTGLSVLRDPVTMSWRDLACSMISVSDNTAADVLLRRV-GL +AHVNETLSDLGLERTRVLGGTADVHRAYDAVLASATTPREMTRLLAAVWSDRAASPERCR +FARELLGAQAW-QHRLRSGFPVGVRVAGKTGTLA-AVRNEVGVVQFDGERPVAVAVFTRA +ARAELPRADAVIGQAARLAVT-- +>[subseq from] serine hydrolase n=1 Tax=Asinibacterium sp. OR53 TaxID=925409 RepID=UPI000479DA06 +-qHLQQQITQLIAGFHGDIGIYVHDLKKNRTI-AINADTVFPTASMVKVPILTGIMDKIH +KKELDYHQVLTYKDSLLYEGVDILGSFKNGEIELSKVMMLMLTMSDNTASLWLQTLAGKG +TRINELMDSLGLKVTRVNSRTPGREVNRNMYGWGQSSPREMASLMEMIVKKQVISDSSSQ +MMLRLLGRNYW-DENAISQIPSDVFVASKSGAVD-ATRNEVLFVNGKKC-SYVFCICTKN +NKESTNEAWVLTRKLSKLLWEYy +>[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00038297F6 +----VARIHAALADAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCVLVALHEQAA +RGALDLAEQVECGPKERTAPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +DTVNATTARLGLTRTRAVHSFGEMLAALDPERTNRSTPRDMTRLLGAVWRDEACTPEHGA +AIRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5UNY7_9BACT +--TLSEELERLGGESKARIAVALHDLETGFRF-SLRGDRWFHAASTIKVAVLLAIFRAAD +EGRLRLDHSLHVRNRFFSAGFPFHYESIGRTAKISALAEGMITASSNLATNLLLDFV-GV +EYARRVLRNALVDSVELWRGVEDH-AAHERGINNEATANGLLKLLSAI-RGDFLSNGSKQ +EVIRILLEQRF-DSMIPAGLPAHATVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF +GQ-EIEGRRETVAAISELIYR-- +>[subseq from] Uncharacterized protein n=1 Tax=Sporomusa silvacetica DSM 10669 TaxID=1123289 RepID=A0A259U919_9FIRM +---LSEQVKNFSTQKEAQYAIYVRPLNQAGQD-VVLNSHKMASASLIKIPIMIEAFNQKN +QGKLDFNERFTIRHAETVEGGSVYNLPDGTVLTIGQLVELMIVQSDNSACNILIDKL-KM +ENVNAMINKLGCSDTILQRKMMDFEA-VKQGRQNYTNVTDMANVLEKLYNSKCLDPKSDK +AMLEILKRQED-NLIIPAQLPHHIKVAHKTGELD-GMNYDCGIIYGQSHN-YILCMMAEN +VKD-E------------------ +>[subseq from] Beta-lactamase class A n=1 Tax=Anaerocolumna aminovalerica TaxID=1527 RepID=A0A1I5GLM8_9FIRM +-----------LQKITGKAGFYYKNLVTGEQI-TFQEDMPFQAASVIKIPILIEAFTRLE +TGSLHKTDLFTIKKQDKLPCGALTYMHDGLQVTLEDLYTLMIILSDNTATNLLIEHL-GM +DQINNTMQKLGCRQIKLNRYLFDSEKA-ALGIENYISAGDIAGLLEKMYHGELVSKEASV +EMLRILKNQRL-NGKIPFFIHGKADIAHKTGEDD-GITHDVGIVYG--KEPFIICFCGNE +--VDVPAYERLMQDISYALFK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. YR288 TaxID=1882766 RepID=A0A2M8YVQ4_9BACI +-------VRQWSSMYRGRVSYLFET--PEERI-EQGATNVYPSASTIKLLIAVEACRQID +SGVILVQQTIAVKQSDLVGGDGILHVYPYLSVTVKELVLLMLILSDNTATNMLIALL-GQ +DRIQACINDLGLENTQLNRQMMDAQAAVEG-RDNVITAADLLTCLKVLYREDVLSKDSRD +FLKESLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLFTHHKR-CYAVVLIDG +LE-HNEYGRRLIADLGRIIS--- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus flexus TaxID=86664 RepID=A0A4P8XCF7_9BACI +-------VRQWSSMYRGRVSYLFET--PEERI-EQGATNVYPSASTIKLLIAVEACRQID +SGVILVQQTIAVKQSDLVGGDGILHVYPYLPVTVKELVLLMLILSDNTATNMLIDLL-GQ +DRIQACINDLGLENTQLNRQMMDAQAAVEG-RDNVITAADLLTCLKVLYREDVLSKDSRD +FLKESLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLFTHHKR-CYAVVLIDG +LE-HNEYGRRLIADLGRIIS--- +>[subseq from] serine hydrolase n=2 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=UPI001402DB02 +---------------QHEIGVAYLNLDSGDTF-FHNEKTVFHAASTMKTPVMFQLYRMRD +AGQLSLEDSLPVINESIVDGSNYSMGNINNKMAIRHLIEAMIATSSNLATNILIELA-DP +EAVMATLKETGADGLSVIRGVEDLKA-FDQGLSNRTDAYGMMMAMKAVFDSQLVSVKSRQ +EMIGILKSQQF-NEMIPAGLPAGTSVAHKTGRIT-GITHDAAIVMPENDSPFVLVILTRG +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Niabella aurantiaca TaxID=379900 RepID=UPI00037F906D +--KLKTLIEKAVSDFHGDIGVYVHHLKRDRFV-AVNADTVFPTASIVKVPILAGVFQKIS +QNELKLSQEFVYDAKRAYGGSGLMQFYKDSATDLSTMISLMLTYSDNVAAIWLQELAGGG +AAVNPLMDQLGLPHTKVNSRTAGRQDIWKKYGWGQTTPREMARLFTLIRQGKVIDARYSD +KMYRYLKNQFY-NGRSLSQLPATVSTICKTGSVND-ARGEVVLVNAPGGD-FVFCILTKN +NKTDDNEAEVLTRKLANIIWNHf +>[subseq from] serine hydrolase n=1 Tax=Actinocorallia herbida TaxID=58109 RepID=UPI000F4B44B4 +----------EFRDAGVHGRLHALDLDSGAEV-AAGADEAVVLASVFKVPLLVAFFRRAA +AGELDARAQVVLPPEARIAGATGTSVLLDEVMSLRDLACLMITVSDNTAADAVMDHV-GL +DHVNRAMAELGLDRTRIVGNARDLHAALDPALATRGTPREMTRLLAAVWRDEAAPPDACA +LMRRMLGLQVW-PHRLASGFPDDVVVSGKTGTLPT-VRNEIGVVEYPDGGRYAVAVFTRS +RSSAQPRADAVIGTAARLAVQ-- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=A0A1S2C783_9BACI +---------------RSNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEVFRQVD +EGLLTLTSVIQRTEKNTVGGAGVLGALPQLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECARNIGLKKTVLNRYMMD-ETAVKQGVDNYTCASDIVECLREIYKGNFLKKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinocorallia herbida TaxID=58109 RepID=A0A3N1CS83_9ACTN +--------EAEFRDAGVHGRLHALDLDSGAEV-AAGADEAVVLASVFKVPLLVAFFRRAA +AGELDARAQVVLPPEARIAGATGTSVLLDEVMSLRDLACLMITVSDNTAADAVMDHV-GL +DHVNRAMAELGLDRTRIVGNARDLHAALDPALATRGTPREMTRLLAAVWRDEAAPPDACA +LMRRMLGLQVW-PHRLASGFPDDVVVSGKTGTLPT-VRNEIGVVEYPDGGRYAVAVFTRS +RSSAQPRADAVIGTAARLAVQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Lactobacillus pentosiphilus TaxID=1714682 RepID=A0A1Z5IZ26_9LACO +--------QRCAHSASGETSIYVDNLKAKHPViLHN--RTQRSASVIKLFIMVTAFRQIK +AGQLSLNQEVRVPKADRVGGTGELAQENVSQLTVSKLLTLMIRNSDNSATNVLIDRLGGI +NVINQEIKRLGCTQTQLQRKMLDYQ-ALKAGKDNVTSAKDVGSLLVRLAQHRVLGAPYDA +EMLQLMTNNAN-QSKLSALINKKATVYNKTGEFDYGVQNDAAIVKKGSQ-TFVAVVLSQK +GT--QRKQISAMQQLGKQLY--- +>[subseq from] Beta-lactamase class A n=2 Tax=Paenibacillus sp. VMFN-D1 TaxID=2135608 RepID=A0A3D9GSY3_9BACL +-----------AEKDGIRMSVGIRDLSGHETL-LLGSQEPYMPASTIKLAVVSALMLQVD +RGELSLADQVRVTPEDVVGGSGSLQTSFPQDLTLERLARLMITQSDNTATNVLIDKV-GM +DNVQQLMDQLDLRTMHLGRKMFATA--PSPAQDNYIDAADLTELLGQIYQGSFLSVSSRN +QIIAWMARQEV-NTKFGAALT-DAPIAHKTGENAN-VTHDAGYFLVPGHE-LAVSVLLQV +TTEAQRIGNPIVQKAARAIYS-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E7VY66_9CHLR +--KLIQRLNNIPNEFKGLCGVCIYDPDTKWYF-GINDDMTFPTASSIKIPILIKLLSDAD +KKLINLSDEIVITEQMKSRGSGVIHKMTGSVMTIENLAILMINLSDNTATNLCIDIA-NQ +KEINEMLSDYDFGTMKLNRKMQDYQ-AINEGKENIATPKEMNLILQMLDNKSLFNESVSN +KTLDILAINKS--TPISQPLPENIKVAGKTGGMP-GVRCETAIVYLKNRR-YILTVMTSY +GGQS------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gastranaerophilales bacterium HUM_10 TaxID=1916229 RepID=A0A292RS03_9BACT +---LKSQLEGLMAQYPIKPAIYVWEYENGKFV-DINGDSLYSAASIIKLPVLIRLFKSIE +AKQMTIYDDMILTNYYQSPGSGNLQYAQTGRYSLDQLAKTMIQDSDNTSTNMIMAKLGGM +DDINAGLRDWGISKTYVRIWLPDLTGT------NKTTAKDMAKLLYNLDNPGFLNINSRE +YIIDYMSHVKN-NRLIAAGLGDGALFVHKTGDIGT-MLGDAGIVYAQNGKKYIVVILANR +PH-NAPQGKDFIVKASSLIYK-- +>[subseq from] Serine hydrolase n=1 Tax=Xanthomonadaceae bacterium NML93-0792 TaxID=2032566 RepID=A0A2A3VGL1_9GAMM +------------------------------------------------------------ +---------------------------------------------DNMAIVGLRNAPAGE +ERLVALARALGVPRSALKASLEAVFDAYYRGDRNQATLPAFATLLERLAAGELLSADSTA +RMLEHMRGISTGDRRLSAGLPPGTDFAQKTGTQVR-RACNVGIVDADAGREGATVVLCAE +DFDALGQAEQAFQAFGRAL---- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A6B0XEA4_9BACT +-----AALRQTAAAFDGRMGWHLEELTTGQVH-QYRADERFPTASVIKIAVLVELFHQAE +TGRLSLDDRHRLRGDISTHGSGVLQIAQDEPLTLRDYARLMMGISDNIATDFLMGLL-GL +DQINATLARLGCANVRAAATMGRYHYFGDSLENNVAAPGELASLLAAIYRGQIVSAAASK +AIIELLKTGRD-TRMIRHYLKSDVVVAHKYGSSGI-IKGDAGLVFLPGGPLVVVAFALAR +D--DGPAAAEAIAEITRLAV--- +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013A5AEE2 +------------------------------------------------------------ +------------------------------------------------------------ +---TAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTFRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] serine hydrolase n=1 Tax=Rufibacter roseus TaxID=1567108 RepID=UPI00082C3913 +-tKLQQKLEALVKEFDGEVGIYVRHLKTGKAV-AINADTLFPTASMIKVPIMVAMFDKIE +RGEINPNAQLRYRDSLYYAGEDIVGNFKDSAVALGKVQMLSITTSDNTGSLWLQQLAGGG +TAINAWLEKNGFEKTRMNSRTPGRRKNWEQYGWGQTTPREMANLVTMIREGKAVSPAASE +RMYRNLGRIYY-DSYALSKIPPYVHTASKSGAVNQ-SKSEVVLVNAPNGD-YVFCIITKN +QKAPDNAGAVLIQKVSETLWKHf +>[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus faecis TaxID=862114 RepID=A0A5D0CUN6_9BACL +-----------AATKGIRVSVGLKDLSGNEET-LLGSKEAYKPASTIKLALVAALMQQVD +RGALTLEDTVTVEPDDVVGGTGSLQKKFPQEVSLERLARLMITQSDNTATNVLIDVV-GL +KRVQELMDQLNLEVMHLGRKMFAAA--PTPEQDNFINAADLITLLDRIYKHSFLTEKSKD +TIIGWMLAQEV-DTKFGAALQ-GAKIAHKTGENAN-VTHDTGYFLVPGRE-MAVAVLTEV +TTEAQAIGNPVVQEIAKAIY--- +>[subseq from] serine hydrolase n=1 Tax=Anaerocolumna sp. CBA3638 TaxID=2696063 RepID=UPI001373AFDF +--ALQKAVEEEIKEAQAKISLYIKNLKTGEVLfQHKEDLSVVSASIIKVPIMVAALEEIQ +KGVLSKDTLVTVPKSTILEDSEVFE-YGERQYTLDELLVWMIINSDNTATNSLIDLL-TM +DKINQTCRQLNLKVTKLERKMLDFDA-VKLGYNNYTSAMDMCLIYKALYDKSILTSDLCD +YAVSILLRQRHKQNSMR-YITDEVKIAHKTGSLDF-LNHDAGIFYLKEND-YYFGAFVWD +AP-DDVYGMKWIGRVSKMVYEYy +>[subseq from] serine hydrolase n=1 Tax=Bacillus farraginis TaxID=254757 RepID=UPI0007170DEC +-----QSVEEIITSTQARISIAVE-IDEQRII-EKDSDREYLSASLIKIPIMMEAYRQSE +LGTICLTDLIEIKDFQKVGGSGVLHSLTGGTLSIKDLITLMIIVSDNTATNIMIELL-GK +DNINQFCRDIGAHHTKVERKLMDEQAK-AEGYENITTASDMICLLKELDQNEILSKNSTL +DILKCLSAQQF-RHKLPGLMDQDMKIANKTGEME-GIEHDVAIIHYGGK-KAYIAVLIDQ +LEQN-FLGQVSIAKIGESV---- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536R0B4_9CHLR +--------RDALRSLPGEASAFACDLDGRELF-CERADELFPAASVIKLPLVMALYADAA +RGHIDLEERLPVG--DRIDGSGVLRHLRDVESSLRDLAMLAIIVSDNTATNRLIERF-GI +ARVNERMREWGCPHSLLARAMFDFEAA-KRGHENVMTARETAALLLRLMRGECEGRAASD +AVLALLAQCQD-RSMLRRYLPHGAKVAHKTGTLDE-SRNDAGIITGE--PTIVVAGFTRR +LRDTE------------------ +>[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. TaxID=1506 RepID=A0A352NVK4_CLOSP +-------IKEKIKNLKGKVGFCYKDLESGYSF-GVNEDDPFIAASIIKIPVLIEAYRKFK +EEDLSKNELVEIRESDRVPSCGAAYIHPGAKLTLKDLCILMIILSDNMAANILINKL-KM +DDINSTMKKLSLKKTRVNRILFDSDAQ-KSGKENYFAPGEILRLFEMMWNGSLISPDDSR +DMLEIFKLQQI-NYKMPYLLPEDICIAHKTGDDD-GITHDAGIVYAK--RPFILCFASNE +TD--VNETDEFIRQTTEEIF--- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 218-3 TaxID=2559919 RepID=UPI0010F78C47 +--------QQTMGKLGGQNSVYIQ-TTTGQTY-QWHN-QSQKAASDIKLFILATVYQQVA +AGKLNLATTYTLKATDKVGGTGSLQGMATGSFTIQELLHYMMTVSDNTATNIVIDEVGGI +SAVNQEIKRLGASQTVLRRKMMDQK-ALTAGRDNVTSVRDLGQLLMKLWHHRLISTAADT +AMLKLMAANTN-HTKLPKLLPGTRTVYNKTGEFDYGVENDAAIFVQGQRA-VVLVALSQG +GQLS--QQ--------------- +>[subseq from] Beta-lactamase class A-like protein n=1 Tax=Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) TaxID=405948 RepID=A4FGH3_SACEN +--------EPGWADFPGRVGFAAWDLDEREPV-LFGARRVVHPASTIKVLVMLTALREVQ +RGGLALDTEVRFP-DERVGGAGVLKDLPGLRLELADAITLMISISDNTATNAVIEAV-GF +EAVGELAAELGCEGTQVQRLLMRVQDP----GRNTTCALDQARILDSLARGTVLPPRLTQ +HALWVLSRQQV-RDRLPALLPEGARCWNKTGEID-GSRHDVALIGDHERPRAVVAVLVDE +LA-DHRAGAARIAGLGLSVYE-- +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. UR1 TaxID=1704277 RepID=A0A2G7H0K5_9DEIO +-------------GFAGTVGLWVGTPQGEALA-TLNGDRVFPAASTIKVPLLVMALQAAQ +RGDLSLEDRVALQAADRVPGAGVLHELGAGLLSWQDVLTLMIVVSDNTATNLTIERL-GV +GAVNGWLGAHGLNGTRLVGKLDQRNEAQRRGERNATTAADQARLLRLLLGGDLLDPPHTA +LALSILGRQQY-RDLIGRGVPADYRVASKSGELT-GVHHDVGVIFTP--RPLVVALLSEG +GQREHPENRDVMALASA------ +>[subseq from] Class A beta-lactamase n=1 Tax=Clostridium sp. HMb25 TaxID=2044259 RepID=A0A2N0KCZ3_9CLOT +---LKLNVLNLCSRIEGKKAIVIEDLKTGQAV-EINRDEVFPAASLIKVPVLSALFRMAK +ENQIALDERIELEKDSRIGGFGILKDLGDGLPAVRDLAVLMITLSDNIAANLLIDRI-GM +SQINSELQAMGMKHTVLQRKMMDSQAK-ERGLDNYTSAGDMQKLMKAILESSF-----RG +DILDILFRQQC-NNKLPALMEGGVRFAHKTGDLP-GVEHDAGIICTDDRE--IIAIVLTD +ELADNREGIWLNQEIGKLI---- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus agri TaxID=51101 RepID=A0A3M8AJ30_9BACL +--DLEKSLSAILQEAKGAWGVVVKELANGAYF-AHRPDELFIAESVIKVPIMAAVYAACE +QGKARIDAQLALRKEDLVGGSGFLYALSPGLLSIRDLVTLMIIQSDNTATNMLIDLV-GK +EQIDRTMREVGMERSRYSRKLMIYPQD--VTENNMITAGDVARMLEQIACGGRFSRWASA +DMIAIMQKQQV-LNGLPSQLPAAWELACKSGWDT-GRQHDVGILSVQGR-QFAIAALSQD +VRA--EAALHTLGLLGRAVYD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. PRKS01-65 TaxID=2697029 RepID=UPI0013DAFDD8 +--SIARRIGAAFAEAGVTGHLHAVDIDSGAEV-DAGADQPVVTASVHKLCLLVALHEQAE +AGRLDLAERVECPPDDRTSGPTGLAAMLDPVISLRDLAYLMMAVSDNGAADLLLRRV-GL +DAVNATTTRLGLERTRALHTFRELFAALDPARTNHTTPRDMTRLLGAVWRDEACLPGHCA +AMRRILGLQVW-PHRLASGFPDDVRVSGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRS +ASATLPAADAVIGTAARMAVD-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia coubleae TaxID=356147 RepID=UPI00083244B5 +--------------------LHARRCDSVAEI-SVGGRDRVVMASVYKLLLCVAFYREVD +HGRIDPAGRLTIDPADCTPPTGIAALHDPITLSRRDLVTSMMTVSDNAAADVLLGEL-GL +AAVADMAVELGLTETRVVGGTADQHQAYDPAYASATTPEEMTRLLWRLWSGDVLSTESTE +FVRAVMRNQIW-PHRVAAGFPRGVVVAGKTGTVGI-IRNEVAVVEFPGEIPVAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5P0N1_9BACT +------------KRKARAIAVAIHDLETDFRF-SLSGDRWFHAASTIKVAVLLAVFRAAD +ESRLRLDDSLHVRNRFFSAGDGSIYHSIGRTARISSLAHAMISGSSNLATNLLLDFV-GV +EYARKVLRDAQVHSVELRRGVEDH-AAHEQGINNEATANGLVTLLSAI-RGDFLSNESKQ +EVIRILLEQRF-NSMIPARLPPHAAVAHKTGEIST-ACHDIGIVYLPEREPYIAVILTEF +D-ADRNGRRETVAAISELIYR-- +>[subseq from] Serine hydrolase n=1 Tax=Xanthomonadaceae bacterium NML93-0399 TaxID=2032565 RepID=A0A2A3LLC8_9GAMM +------------------------------------------------------------ +---------------------------------------------DNMAIVRLRNADVGE +PRLEALARELGVPRSGLDASIEAVFDAYYDGEDNQARLPAFGLMLERLAAGELLSPDSTA +IILGHMRQITTGDRRISAGLPAGTDFAQKTGTQIR-RACNVGVIDPEAGEGATVVLACAE +DFDDISQAEQAFQAFGRVL---- +>[subseq from] Beta-lactamase domain-containing protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1K376_9ZZZZ +------------------------------------------------------------ +-----------------------------------------------------------P +KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAE--------- +>[subseq from] Uncharacterized protein n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=A0A0E3UPQ0_9GAMM +------------------------------------------------------------ +----------------------------------------------------------GE +PRLQALAALLGVPRSQLKASLQAVFDDYYASGRNAATLPAFARLLERLVAGELLSESSTA +LLLGHMREIGTGGRRIQAGLPADADFAQKTGTQQQ-RACNVGILDPDRGDGATVVVACAE +DFGELAQAEQAFQALGRALAQ-- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=A0A5S4Z5I5_9BACI +---LREEMMGIVQECSGKVSFSVLL--DDESL-SWEEDRRISSASLIKLPILMAAYEQIQ +TGRLRADAMIVLRHEDHVEGAGVLNGHDGLTLSIEDLLTLMITVSDNTATNRLIELI-GM +DSINRFCLDWNLKGTFLNRKMMDFPS-LEMGKDNWTSSEDVVSCLTLINEGPF-EEASRK +KMLTILSRQQF-RDKLPALLGDDVKVFNKTGELP-GVEHDCAIIESASGKYAYVAVLTYE +LPAP-EEGRRVIRTMGKLIGD-- +>[subseq from] Steryl acetyl hydrolase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A3R6BSH1_9BACT +---------------------------NGELYcGHQEDSAFAMHSVMKFPQALYVADYLH +KKGLTLSDSVLVNKDSLDAWSPMLSIFEGMRFTFAELMEWSLKQSDNNACDLLFASCGQP +DAVEKYIHTLGFKDIHVQLTEKEMKKNPHRAIENSATPKEMARLLEWFYLHRD-DNKNLS +FIWDTMADCNTGQQRIAAVLPKDGKLIHKTGSGFRQDRNDVGIVLLPDDSHLSIAIFLQK +SKEEKEVAEI------------- +>[subseq from] Beta-lactamase n=3 Tax=Clostridiales TaxID=186802 RepID=A0A174GDL8_CLOSY +---LKLNVLNLCSRIEGKKAIVIEDLKTGEAV-EINRDEVFPAASLIKVPVLSALFRMAK +ENQIALDERIELEKDSRIGGFGILKDLGDGLPAVRDLAVLMITLSDNIAANLLIDRI-GM +SQINSELQAMGMKHTVLQRKMMDSQAK-ERGLDNYTSAGDMQKLMKAILESSF-----RG +DILDILFRQQC-NNKLPALMEGGVRFAHKTGDLP-GVEHDAGIICTDDRE--IIAIVLTD +ELADNREGIWLNQEIGKLI---- +>[subseq from] Uncharacterized protein n=1 Tax=Atopobium vaginae TaxID=82135 RepID=A0A135P9T6_9ACTN +-kELQQQIEELTQPYGSSVSVCIIDASNGNYC-HVNSDKALVSASMIKLAVLCEYMHAVD +NGQLDPADRVALKNMNVVGGTGLIQTERHASYTYDELCRYMIMYSDNTATNVLINKL-GQ +DAINERVQALGCKNTSLNRQLMALNTN----TENWISARDAATILYKIKNGTAASSAMCA +KALEYLSKQTD-NEGMAEGISSG-AFAHKTGSLRS-MRHDGGIVLG--KHPYVIVALCDI +GAGN---ANKLMKEIAQKA---- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7M3R2_9BACT +---LRDRLEARISRAPAQVGLYYRNLAGSDSI-LIGANLRLHAASTMKVPVMIQIFRDAD +AGLLRLDDSLTVHTASLVGGGAFTYALVGRNRSVRELLELMITRSSNLATNILIERV-GA +SRAQASARAMGAWSIQVLRGVEDGA-AYRAGLNNTTTARDLGVLLGAIATGRAASRGACD +SMLAILGRQEF-NEGIPVGVPPGTRVAHKTGWIGEVVYHDAALVYPSAGVGYVLVVLTGG +IKED-SVGHNLVADLSRLVYQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium sp. JUb78 TaxID=2485111 RepID=A0A4V2TQP0_9SPHI +-kKLDRQLRALTQDFHGDIGIYVKNLKTQKEV-LIQADSIFPTASIVKVPILAGIFDKIE +KGELALDQKFTFRSSQQYGGSGLMQFFKDSSTDLATMIGLMISYSDNVTSIWNQQLAGGG +STINQLMDQLGLVNTKVNSRTEGRNEIWKKYGWGQTTPREMATLVALIFQGKVVSTKASD +KMYRYLGNIFY-NERSLSQIPAYVKTASKTGSVDE-ARGEVVLVNAPSGD-YVFCVLTNN +IKTKNNEAEELTRKISHLLWNYf +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E6WQ03_9CHLR +--KLEDDLIDKLDQFPGVAGVSIKDLIXGNDI-SINGNEIFPTASIIKIHILTYLLKMAE +SGSIDINKRISVDKNKFTGGTGILKYLKGKPLTLRDIAVLMIMLSDNTATNICIDLL-GI +ENINSFISDMELSXTKLNRKMMDEK-AIIXGNENLSTPKELTKMLEKLYLG-LPSKAVSK +YVLEIMSEPKN--SCLNLSTPSDITVANKGGGMEH-VRGDSGIIFLENN-PYIISILTKS +CYKGSGFQEEYIMNIAKDVFEIf +>[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A3D4YJE3_9FIRM +---MKQRILEQIASMPGHNGMYFKNLITGEKI-EYRSDESFGPASVIKLPILMHICQLAR +QCQVRMDEKIRCRHADKLGGCGALRAFNDEPVSISTLCELMITISDNSATNLLIHRF-GM +DALNESFRQMGLSVTRLNRILFD-NEAASRGIENEFSPAEMGDLLEQIYRRKFVDETTSI +YIEDMLMKQQI-NHKIPGIIGDAAPIAHKTGEDE-GISNDVALVYAPE--PFVLCYAGNG +TN--VPEFENFIRK--------- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 398-2 TaxID=2559920 RepID=UPI0010F5175E +--------QQTMGKLGGQNSVYIQ-TTTGQTY-QWHN-QSQKAASDIKLFILATVYQQVA +AGKLNLATTYTLKATDKVGGTGSLQGMATGSFTIQELLHYMMTVSDNTATNIVIDEVGGI +SAVNQEIKRLGASQTVLRRKMMDQK-ALTAGRDNVTSVRDLGQLLMKLWHHRLISATADT +AMLKLMAANTN-HTKLPKLLPGTRTVYNKTGEFDYGVENDAAIFVQGQRA-VVIVALSQG +GQLS--Q---------------- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophaga flava TaxID=2259036 RepID=A0A365Y1L3_9BACT +--RLQQGLQQIADNFKGTAGIYVQHLQTGEWA-SINGDTIFPTASIVKIPLLVGLFNKID +KGELGYHQSMVYRDSSRYGGSGLMQFFKDSSTEVSVLAALMMAYSDNTTSLLNQQLAGGG +AAINQLLEQYGLKDTRVNSRTPGREDNRKIYGWGQTTPREMATLLAKISRGEVISRAASE +RMYRLMTKGYY-DEQALTQIPPYVQAAAKTGSIDE-SRSEVVLVNAPHGD-YVFYVGTKN +IKDADNEAVEMIRTISAYLWKHf +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus agri TaxID=51101 RepID=UPI000471F30E +--DLEKSLSAILQEAKGAWGVVVKELANGAYF-AHRPDELFIAESVIKVPIMAAVYAACE +QGKARIDAQLALRKEDLVVGSGFLYALSPGLLSIRDLVTLMIIQSDNTATNMLIDLV-GK +EQIDRTMRELGMERSRYSRKLMIYPQD--VTENNMITAGDVARMLEQIACGGRFSRWASA +DMIAIMQKQQV-LNGLPSQLPSRWELACKSGWDT-GRQHDVGILSVQGR-QFAIAALSQD +VRA--EAALHTLGLLGRAVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7MLB3_9BACT +--SLSDKIAPLTKAHEGKVAIAVKNLTSGETY-YHQAGLVMPTASLIKLGVMTAAYRLSD +QSEIRLNDMVLLQKEDKVPGSGILTSNFSEGFPLKDAIRLMIAYSDNTATNLVLDHI-GI +RTVNTTLTQMGFPNTRINAKVFKGSTQTKKYGLGSTTAKETIDLLELIYTNKAATEKSCT +AMIEHLKKCED-KDMIPRELTKLKSIAHKIGAVSD-ARTDAGIMYFDGG-PVVICVLTAE +NKTSENSAEILIGKIGLTVFDHf +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudonocardia kunmingensis TaxID=630975 RepID=A0A543DNP5_9PSEU +--ELEREIRRTFADAGVHGRLHAVPLGGSREV-GVDPDEPVVMASVYKVPLLVAFCRAVD +AGGLDPRERVTVDPAERTAPSGLSVMRDPVTLSWRDLASSMITVSDNTAADVVLRRV-GL +AAVHEVLQDLDLAHTRVQGGTADVHRAYDPALDSATTARDMTRLLAAIWGDRAASPRRCA +FARDLLGAQVW-SHRLRSGFPVGVRVAGKTGTLG-AVRNEVGVVEFDGERPVAVAVFTRA +ARAELPRADAVIGQAARLAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Fictibacillus solisalsi TaxID=459525 RepID=A0A1H0AB32_9BACI +--ELKNRLNGIIDPLTGEFAYYIET--EEGYI-GENEEKVFPAASLIKLPILIEAFRQKE +AGLLDLSLPVPIKPKDKVGGAGIINHLSPDALTVLDVLTLMITVSDNTGANVMIEQA-GR +ERINALLTALRCHRTVLKRKLMDFK-AIQEGKNNYTSAKDVVLLLKEIHHGKLMKNESRV +MMLDILRNQQF-RHKLPGSMDEEVMIANKTGELQ-GTEHDAGIFEYKDTT-VIAAVLTKN +LSNEAEARHK-LAAIGTAI---- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. RU2C TaxID=1907304 RepID=A0A1N6XAC1_9BACI +-------VRQWSSMYRGRVSYLFET--PEERI-EQGATNVYPSASTIKLLIAVEACRQID +SGVILVQQTIAVKQSDLVGGDGILHVYPYLPVTVKELVLLMLILSDNTATNMLIDLL-GQ +DRIQACINDLGLENTQLNRQMMDAQAAVEG-RDNVITAADLLTCLKVLYREDVLSKDSRD +FLKGSLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLFTHHKR-CYAVVLIDG +LE-HNEYGRRLIADLGRIIS--- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A521NA06_9BACT +-kKLQAQLTELVKGFRGNLGLYVHDLTRNREV-AIRADSLFPTASMVKVPILTGLMRKIE +SGELQYHQPLVYKDSLLYEGEDILGSFKNGEIEMSKVMMLMLTMSDNTASLWLQTLAGTG +TAINRLMDSLGLVNTKVNSRTPGRENYRSEFGWGQTTPREMATLLEKIVKKEVISEAASE +KMLRLLGRNYW-DEEAISQIPSDVFIASKSGAVN-ASRSEVLYVNGKKA-RYLFCICTKN +NQNSSNEAWELTRKISRLLWEYy +>[subseq from] serine hydrolase n=2 Tax=Deinococcus wulumuqiensis TaxID=980427 RepID=UPI000346526A +------------ADYTGEVGLLVTDFGGRELY-ACAANAPFPSASTIKLPLLLMALEQAG +RGDLDLAERVTLRAEDRVPGAGVLHELSPGLLTWQDVLTLMIVVSDNTATNLLIERL-GQ +DDFNAWLTARGLNSTRLQQPPERQNAAQRRGERNRTSARDQVALLLSLLRGDGLTPQMQQ +LGLDILGRQQV-RDLIGRGIPAGYRVASKSGELR-GVHHDVGLLWTP--RPLVVALLSQG +GED--PREHPANRDVTRLAA--- +>[subseq from] serine hydrolase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013C80B86 +--EITDRIRAVFADAGCTGWLHARRCGSPAEI-SVDAHDRVVIASVYKLVLLVAFCRRVD +AGLIDPRAPLTVYPADCTPPTGIAALHDPVTMSRRDLATSMMTVSDNAAADVLLGEI-GL +GAVEELLTELGLTETRIVGGTADVHRAYDPSYASATTPEEMTRFLDLIWAGGVLSPEQTG +FVRAVMGKQVW-PHRIASAFPRGVGVAGKTGTVGV-IRNEVAVVEFPDEYPVAVAVFTRA +ARADLAVVDAAIAEAARVAVT-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine metagenome TaxID=408172 RepID=A0A381UZQ6_9ZZZZ +--DLASRIEASLNSLNAKTSFYAKHLPSGREI-AIRADEPMNALSVIKIPIMVLAYRDAD +AGTLELDERYQIQPEDMRRGSGLLQSFSPGIPTYRDIITQMIITSDNTATDVVIKRL-GL +ERVNTMLAEMGFDQTRLRATTGELFRGDSTQWLGRITAREISHMLEAIEENELASPESSD +EMIGILRRQFY-SSRLPQQLRGRASIAHKTGDWPPHAGNDAGILYYEGG-PTVVAVFTNQ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Bacillus massiliogabonensis TaxID=1871011 RepID=UPI000C837297 +--ELKDNVYTEASKCRGRVGLIIEA--EDKRI-EINSEGKFSSASLIKVPILIECFRQAE +RGTLNLQQSIQIASVEKVGGAGVLQALSKDLLKVMDAMTLMIIVSDNLATNLLIDLI-GM +DQINQGMRELNLQHTELNRKMMDFT-ALTNGIDNYTTASDMLTCLKEIGQNRILSKESAS +KVKEIMENQQF-QNKLSDQIDDAFKVANKTGELF-GIEHDCAIIEYEKK-SVYAAVLIDQ +LRAP-KDGRQTLSSIGQLISQ-- +>[subseq from] serine hydrolase n=1 Tax=Filimonas lacunae TaxID=477680 RepID=UPI0012432BA7 +--KLEKQLRAEMAKYPARFGFAFKDLGTEQTF-LLNEKLAFHAASTMKTPVLMEAYKQAA +EGRFSIHDKIRVTNSSIVDGSSFSYQMVGKELAISDILHRMITKSSNLATNIIIDLV-GA +KNVMETMKGLGANDIQVLRGVEDQK-AYDAGKNNTTTAYDLMLLFEQLGNGNFINKMASA +EMIRILQDQHF-REIIAGKLPEEVRTATKSGSITK-IAHDSGLVFLPDGRKYVVVLLSSG +FDK-HEEAVNVLSGMSKMIYD-- +>[subseq from] Beta-lactamase n=1 Tax=Firmicutes bacterium CAG:145 TaxID=1263005 RepID=R6FKV9_9FIRM +-----ERLRELISPLKGKIGFYYENMIDGDKL-SYNADHVFTAASVIKVPLFMYVAKLVS +EGKLSWDQKVIVREGDKKPSCGALLSLSGDIVDIESLCRLMITLSDNTATNMLIRTV-GI +DELKRGFAQMGLVKTQIQRELFDDEAA-AKGLENYISPEEIAMLLKQVYQRGFVSRQVSE +KIENVMLLQQI-RHKIPGYIGRKKKIANKTGEDSD-TTHDAAIVFAQ--RPFVLVITSND +TD--VPQTERFIREAALELY--- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonas sp. SG8_23 TaxID=1703356 RepID=A0A0S7Z965_9BACT +-nRLQSDLEAVVHEYEGVAGLHVVDLTTGDRF-AVRDNLLFPQASAIKVPILLELFRRAE +SDPGLLRKRIEMTDEVRTGGSGVLHVLTDGGLSLEDYAIYMIQHSDNTATNVLIDEL-GM +EAVNALSASLGATRTLLQRKMIRPEES-ARGNENLSTPRDAARIMERIAACDLMSEASCA +RVREILELGKGG--PIRAPVPPSVPIAFKPGGIT-GVSTVWGLVGLPDR-PYVIVVMSNY +GG----NGGAVIEAVSGATYDYf +>[subseq from] Beta-lactamase n=1 Tax=Deinococcus soli Cha et al. 2016 TaxID=1309411 RepID=A0A0F7JV60_9DEIO +-----------ASGFAGTVGLRVTDVTGAELI-AWNAERVFPAASTIKVPLLVLALQEAQ +AGRLDLSARVTMQPGDRVPGAGVLHDLDGGLLTWRDVLTLMIVVSDNTATNLVIARL-GV +DAVNAWLAAQGLTGTRLVGKLQQRNEAQRRGERNATTARDQTALLRALVAGDVLDEAHTA +LALDILGRQQY-RDLIARHVPCGYRSATKSGELL-GVHHDVGVLFTP--RPLLVGLLSEG +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Sphingobacterium faecium TaxID=34087 RepID=UPI001290E672 +-tKLEQKIRALTQNFQGDIGIYVKNLKTQKSV-LIQADSIFPTASIVKIPILVGVFDKIE +KGELNLDQKFTYRSSQQYGGSGLMQFFKDSTTDLSTLVGLMISYSDNVTSIWNQQLAGGG +LVINELMNKLGLVNTKVNSRTEGRHDIWKKYGWGQTTPREMATLVEMIYQGKVVSLKASD +RMYRYLGNIFY-NERSLSQIPAYIKTASKTGSVDE-ARGEVVLVNAPSGD-YVFCVLTNN +IKTKHNEAEELTRKISHLLWNYf +>[subseq from] Uncharacterized protein n=2 Tax=Selenomonas TaxID=970 RepID=C4V1H1_9FIRM +-eALGEAIEALSRADSTRYSVYADYPQENRQP-YIYQSESMRSASMIKVFILGTAMEQVR +DGRLSLAQTLTLRAADKVGGAGVLSGYADGSLSLDTVLRLMITESDNTATNMMIDLL-GM +EEINAYITRNGYTDTILQRKMMDTQAAAE-GWENYTSVSDLGRFFRRLYDHACVSTELDE +RMLDYLKGQTD-TECFPAALP-YAVIAHKTGELV-GLYDDGGIIYADGHD-VILVVMTEN +YS-GRERAIRTIRRMAQCAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7PYS5_9BACT +----------------------ARDPVSGFLL-EVNPDLRFHAASTMKVPVLIELARRVD +AGEVRWTDSIPVKNRSLADGSPFSYAAIGARWSLRQLATRMIVRSSNLATNLLIERL-DA +ARVTAGIRRLGADSMVVLRGVEDGKA-FAKGLNNTTTARDLATLLLAIEDRRAVSAASTR +EILAMLLAQEF-NDGIPAGLPPGTRVAHKTGEIT-ATWHDAALVYPPDGRPYALVVLTRG +IPER-GRGVGLHADVA------- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus horikoshii TaxID=79883 RepID=A0A5D4TGI6_9BACI +---LKERVQAVIDSTAGHVSFVIDD-GNGQRL-GKDADVTKKAASLIKIPIMMAAFKQVE +AGRLNLSDRYSIDTRKIVSGAGVIQFMESDTFTLGELLTLMIIVSDNTATNQVIDII-GW +NVVDDFCREQGLTNTKLERKMMDFKAA-EAGLENRTSAHEMVECLKLLYVEDVFSDKSRQ +KMLRILGGQQL-LDKLPFYMDESVGIANKTGELP-GVEHDCGIVTYKGK-KLFVAVLIDE +LV-DNSIGKRAIQEIGKVVEE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax wautersii TaxID=1177982 RepID=A0A1I2FBP4_9BURK +------------------------------------------------------------ +----------------------------------------------------------GP +RRVQALARALGMPESQLQRTMDEAYARFYRRGDNTAPLVDYGAMLERLVRGQLVNAQHQQ +QLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQFQ-RACHMGVIDPQDGRRAIIVATCAE +GLDEQKQAGRAFEALGRAITQ-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. DH-12 TaxID=2072509 RepID=A0A2K2RJA4_9ACTN +----VARIHAAFADAGVTGRLHALDIDSGEEL-DAGADQPVCTASVHKLCLLVALHERAA +RGALDLAEQVETVPGGRTAPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTGRLGLTRTRAVHSFGEMLAALDPDRTNRSTPRDMTRLLRAVWRDEACTPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=UPI000695CD02 +------------------------------------------------------------ +----------------------------------------------------------GE +PRLQALAALLGVPRSQLKASLQAVFDDYYASGRNAATLPAFARLLERLVAGELLSESSTA +LLLGHMREIGTGGRRIQAGLPADADFAQKTGTQQQ-RACNVGILDPDRGDGATVVVACAE +DFGELAQAEQAFQALGRALAQ-- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium estertheticum TaxID=238834 RepID=A0A5N7ILY4_9CLOT +----------YLSDAKLKYSIYIKELNQGEIC-EINQFEIVPSASIIKLFIMGSTLERVS +AGTLSLKDRITINKKEKVPFSILTLLDDDNSYTINDLILLMVIQSDNTATNKLIDII-GF +DSINDFIKKHNFNSSTLQRKMMDNES-RLKGIDNLCNISDCALFLELIYNGKLINEEYSK +LMVSILTHQLD-DSMMKINLPTNITIAHKTGDLDF-LKHDVGIVYTSKT-NYIFSMFTWE +AI-SDNYAKNLIGNISQITYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Woeseia oceani TaxID=1548547 RepID=A0A193LJD0_9GAMM +-nKFQQGIERIADDLPGVLGVAVVDIDGNRVF-GVNESEIFPQGSAIKISILTAMYVRQE +RGEMDLTRSVPIRKADRVGGSGYLTHFSDGDLSLHDLAILMITVSDNMATNILIEQT-GM +DNVNAVMADLGFGDIRLQRRMIRQEQS-ARGNENIATPTSAAKLMQRILRCDLISGEACA +EMQAILAIRHAG--PIQAGTPNGIRVLQKTGSIA-GVATSWGVVDLEGR-PYALAMMGNY +GD--TAEINDSIRQITEL----- +>[subseq from] Serine hydrolase n=1 Tax=Balneolaceae bacterium TaxID=2053516 RepID=A0A651GVV1_9BACT +---LKSDIESYLSGQDGTFAVWFQHLDNPDLHfAINEDTLFHAASTMKTPVMIELFRRAE +QGEFDLSDSIKVENRSIVDGSEFQERMEDEMATIYDLNHAMITYSSNIATNLIIQLV-GA +EETTQTMRELGAEHIEVIRGLYDMKA-FDQGLSNRTTAKDLGIIFERIAKGTAVSPEKDT +MMIDVLKDQFY-RDVIPARLPDDVVVANKTGFIT-GVIHDSGIVYLPDGQSYILIFLSKD +LPEN-RIGTETGVAVSEMIY--- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=A0A5D4S1X4_9BACI +-kDLREDLMKIVHECPGSVSFTILS--NDESL-SWEENRRISSASLIKLPIMMAAFEQIQ +TGSLKGDAMVVLRHEDHVEGAGVLNGHDGITLSIEDLLTLMITVSDNTATNRLIELI-GK +DSINRFCLSWKLKRTFLNRKMMDFRL-LEMGQDNWTSSMDVVSCLRGINEGRF-EEASRR +KMLTMLSRQQF-RDKLPALVGGDVKVFNKTGELP-GVEHDCAILESTSGKIAYVAVLIDE +LQVP-EDGRRAISRIGKLVYDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter sp. 24 TaxID=2183986 RepID=A0A4R6FYT4_9FLAO +--ELQSKLENLIKDFKGDVGVYVRHLKTGKEV-AINADTVFPTASIVKVPILIKIFDKIE +KGELRYTDSLLYTKERIYGGSGLMQFYKDSTTDLRTLVALMISYSDNVTSLWNQELAGGG +EAINELMAEIGLEKTRVNSRTKNRDKDWEKYGWGQTTPREMASILVKIRKRELISARASE +EMYRLLGNSFY-QEYALSQIPPYVQAAAKQGMVNT-SRSELFLVNAPSGD-YVCYIATKN +NQEDDNQAWQLQRDISALLWDYy +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. 4F TaxID=1751294 RepID=UPI000AC13FEB +----VARIRAALTDAGVTGWLHALDIDSGEQL-DAGGDQPVCTASVHKLCLLVALHEQAE +RGALDLTEQVESVPEGRTAPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA +AIRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. GDMCC 1.1288 TaxID=2282649 RepID=A0A3E1Y789_9BACT +--VLQKKLEETVSQFKGFAGIYVCQLSTGRFA-AINADTVFPTASIVKIPLLVGLFDKID +KGELQYHQPMLYRDSIRYGGSGIMQFFKDSTTELSVLAALMMSYSDNTSSLWNQDLAGGG +ATVNKLMEQYGLKDTRVNSRTPGREAIRKIYGWGQTTPREMAALLVKIRRGEVVSPKASD +RMYRLMTKGYY-DEQAVAQIPAYIQVAAKTGSVDD-SKSEVLLVNAPHGD-YVLYVGTKD +IQTDDNEAVMLIRSISALVWKHf +>[subseq from] serine hydrolase n=1 Tax=Flavisolibacter sp. X7X TaxID=2364882 RepID=UPI000EAFC42D +-kKLQRQMEELIRGFGGNIGVYVKNLKNGKTV-AIDADSVFPTASMVKIPILVGIMDKLN +RGELDYHQTLTYKDSLLYEGVDILGSFKSDEIELSKVMMLMLTMSDNTASLWLQSLAGKG +TRINEILDSLGFIHTRVNSRTPGRETARSVYGWGQTSPREMATVMEKISNGEIINPERSA +RMLRLLGRNYW-DEQAVSQIPSDVFVASKNGAVDE-SRGEVMFVNGH-GARYVFCVCTKN +NKTENNEAWVLTRKLSKLVWERf +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SWJ0_9BACT +-sELENRIDSLLNSKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD +FLWQTMI----------------------------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SMS_SU21 TaxID=2069440 RepID=A0A2U2EXF5_9ACTN +----VARIHAAFTDAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHERAA +RGALDLAEQVESVPEGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACSPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] hypothetical protein n=1 Tax=Nitrincola alkalilacustris TaxID=1571224 RepID=UPI00124D92D6 +--DLITQVAALAANEGIEIGFAARLVESGQQI-SLNERQLYPSASVFKVPVMLEVLRRID +RGELRADQRLPLTTAAKTLTTGVLLTLDDGLLTLQDLMTLMIIISDNTATTMLLDLV-GK +DAVNQALHTLGCHDTTVTMNVHEMFLFARKRENTVTTAADMAHLMAMIAAGQAFGPQVSE +QAHLIMRQTQT-TGRVPRFLPY-RSVGNKTGTFR-GLRNDCGIITRADHDHIAYALFTFD +PTR-------------------- +>[subseq from] serine hydrolase n=1 Tax=Clostridiales bacterium Marseille-P2846 TaxID=1852363 RepID=UPI000C83D1D2 +------EIKEALRALPGSISYYYEDLITGAVE-TFEAERPQVAASVIKLPILVEAMRQID +AGEANPDERFIVTGEQKMPSCGALSYHDGLAVTLTDLATLMIILSDNTATNLLIDRL-GM +ENVNRTAGALGLEQTCLRRRLFDAEAS-ARGIENTVSARDMGRLLSGMYRGQVASEHASA +AMLKMLANQRL-NGKLPFYLHAGIPVAHKTGEDS-GITHDVGIVYA--GRPFVVCILTSG +TD--VARAERTMQDVALALYR-- +>[subseq from] Uncharacterized protein n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=A0A147GQG3_9BURK +-rQLAERIARIDQQTPGRLGVYVKRLSDGSTM-NHGTEQAWYLASMAKVPVALAVLRQVQ +VGKAGLGDEMALQDGDRIDVGNIVWNDTGTRYSVRTLVERMLLESDNTAANMLIRSV-GE +DALNDGTRQMGTPNVTLTTFAQVRRDRYYRRNLNTATLQAYGGMLERLVRGQLLPEEPRT +VLYKAMKRDIYTGYRLQAGLPRDMPFIHKTGTQHR-RACHAGVLNPDDLQKALVIVACTA +DLDEQKQAGPVLESVGRAIR--- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gastranaerophilales bacterium HUM_18 TaxID=1916231 RepID=A0A292S2M7_9BACT +---LKSQLEGLMAQYPIKPAIYVWEYENGKFV-DINGDSLYSAASIIKLPVLIRLFKSIE +AKQMTIYDDMLLTDYYQSPGSGNLQYAQTGRYSLDQLAKTMIQDSDNTSTNMIMAKLGGM +DDINAGLRDWGISKTYVRTWLPDLTGT------NKTTAKDMAKLLYNLDNPGFLNINSRE +YIIDYMSHVKN-NRLIAADLGDGALFVHKTGDIGT-MLGDAGIVYAQNGKKYIVVILANR +PH-NAPQGKDFIVKASSLIYK-- +>[subseq from] serine hydrolase n=1 Tax=Salinicola sp. CR57 TaxID=1949086 RepID=UPI000DA134D2 +-----------ERTGTGEIGVHVRRLDDGERA-GWRDAERWYWASLVKVPVAVELLDRIS +RDGADLDDTMTLHASDYVDGAGATNWAAPDTIPLRTLLERMLIDSDNTATDMLMRRV-GL +EAVNRRARSLMDEGIGPITTLIDVRRRYYATGLNSGRLDRYADMLERIDEGEALPAAATA +TLLSIMQRADTGHRRLAAGFQRPWPFAQKTGTQYS-RFCDAGILAPGTPGAVVIVSCLRG +AP-SRREAERTFQAIGRAV---- +>[subseq from] serine hydrolase n=1 Tax=Bacillus flexus TaxID=86664 RepID=UPI000E683C34 +-------VRQWSSMYRGRVSYLFET--PEERI-EQGATNVYPSASTIKLLIAVEACRQID +SGVILVQQTIAVKQSDLVGGDGILHVYPYLPVTVKELVLLMLILSDNTATNMLIDLL-GQ +DRIQACINDLGLENTQLNRQMMDAQAAVEG-RDNVITAADLLTCLKVLYREDVLSKDSRD +FLKGSLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLFTHHKR-CYAVVLIDG +LE-HNQYGRRLIADLGRIIS--- +>[subseq from] serine hydrolase n=1 Tax=Bacillus indicus TaxID=246786 RepID=UPI00068A828E +--------AGILSNCPGRAGACFSW--NGEWL-EAGSSDVFSSASLIKLPVLLTAFRLAE +KGNLDLNEKVKLRDVEKTGGAGVLQALSEDALSVQDLLTLMITVSDNAATNWVIEKI-GM +PKINETIEGLGLVNTKLNRKMMDLD-AIQSGMDNFTSPADMVRCLQAISEGDFVSEDSRQ +KILDILQKQQF-TDKLPYSMDKDLIAGNKTGELP-GIEHDCAIIKYRDT-SVYAAVMIDQ +LEQ-KEWGRKTISEVGNLIYEK- +>[subseq from] serine hydrolase n=1 Tax=Actinospica acidiphila TaxID=304899 RepID=UPI0013C764CB +----VARIRAALTDAGVTGWLHALDIDSGEQL-DAGGDQPVCTASVHKLCLLVALHEQAE +RGALDLAEQVESVPEGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTARLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACAPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Terrabacteria group bacterium ANGP1 TaxID=2569760 RepID=A0A537L3C6_9BACT +---VVQDIERLAGRFSGVLGVWSHSLTSGEMV-EWNAQDVFPAASAIKLPILYEVYRQAG +EERFRLTDTRTVEAADVVPGSGVLKDLTPPVLPVRDLAMLMIVVSDNTAANLMIDLV-GI +DAINRSMQALGLTATVMEYKF---FHAPPSSRGARSTPADLGCLMTQIADHKVLTPGACE +EMLGILRRQHYTD-YVTRRIPEYITVASKSGSIR-GTRNDVALVEGRDC-RYVIAMMSRD +CKDRDNEAAVLLADVSALIYGYf +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudorhodoferax soli TaxID=545864 RepID=A0A368XNE1_9BURK +------------------------------------------------------------ +-----------------------------------------------------------P +QRAEAVRRALALPAGALRTDIDTAYADYYAEGHNSATLAGYGAMLERLVRGELLSPASTD +RLFKAMKFGTRGSYRLEAGLPKSLPLIHKTGTQHR-RACHVGVVQPQDGDATVLAVCAAD +LD-EQRAAGRLFEAVGRAIA--- +>[subseq from] Uncharacterized protein n=2 Tax=Bacillus marisflavi TaxID=189381 RepID=A0A161T698_9BACI +---LREEMMGIVQECSGKVSFSVLL--DDESL-SWEEDRRISSASLIKLPILMAAYEQIQ +TGRLRADAMIVLRHEDHVEGAGVLNGHDGLTLSIEDLLTLMITVSDNTATNRLIELI-GM +DSINRFCLDWNLKGTFLNRKMMDFPS-LEMGKDNWTSSEDVVSCLTLINEGPF-EEASRK +KMLTMLSRQQF-RDKLPALLGDDVKVFNKTGELP-GVEHDCAIIESASGKYAYVAVLTYE +LPAP-EEGRRVIRTMGKLIGD-- +>[subseq from] serine hydrolase n=1 Tax=Actinomadura kijaniata TaxID=46161 RepID=UPI00082F0E58 +------RVEEAFRDAGVTGWLHAVDLDSGREV-SVRGDEPVVLASVYKVPVLVAFHRQAA +AGLLDRTAPVTLRPDGRTAPTGISAMLDEVRMSLRDLALLMMTVSDNAAADAVLARV-GL +DAVNKAMADLGLSRTHIAYDGRDLHAVLDPARTTRSTPREMTRLLAMVWNDEAAPPEDCA +QMRRMMGLQVW-PHRLSSGFPDDVRVSGKTGTLPT-LRNEIGVVEYPDGGRYAVAVFTRS +PLAVLPQADAVIGTAARLAV--- +>[subseq from] serine hydrolase n=1 Tax=Bacillus flexus TaxID=86664 RepID=UPI00099B4E3B +-------VRQWSSMYRGRVSYLFET--PEERI-EQGATNVYPSASTIKLLIAVEACRQID +SGVILVQQTIAVKQSDLVGGDGILHVYPYLSVTVKELVLLMLILSDNTATNMLIDLL-GQ +DRIQACINDLGLENTQLNRQMMDAQAAVEG-RDNVITAADLLTCLKVLYREDVLSKDSRD +FLKGSLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLFTHHKR-CYAVVLIDG +LE-HNEYGRRLIADLGQIIS--- +>[subseq from] serine hydrolase n=1 Tax=Angelakisella massiliensis TaxID=1871018 RepID=UPI0008F91C9F +-dELERQAAALVEANPAHICALCIPLGEEPLF-DLGGKTRVVSASTIKTPILCTALEQVR +EGKLSLDQPVKVDREVILEDSEFFDLGPG-TFPLWELLYWMIVTSDNTCTNVLIDLL-GM +DTINAWCAAHGLENSRVERKMLDWK-AIEEGRNNYTSPWDQYKLFAALYRREILTPELCG +TAWEILLRQRSTDQFL-RYISDDVQVAHKTGGLDY-LNHDCGIFCLPEH-PYYLGVFVSN +AP-KIEGDNRVVGQLSRLAYDY- +>[subseq from] Beta-lactamase n=2 Tax=Intestinimonas butyriciproducens TaxID=1297617 RepID=A0A0S2W053_9FIRM +--------EARLSAIPGHIGFYYQNLDTGEVQ-TFHALDRFQAASVIKLPILAAVFLHEQ +ECPGILSRRILVRDSEKLPGCGALQHIAGDHYDVLSLCRLMITLSDNTATNALIRHF-GI +DTLNEDFSRLGLEDTRLYRLLFDAEAA-SRGKENLFQPRECGLLLERLYRGTCVSSAASE +RMLAILLQQQI-NHKIPGRLPAEFPVAHKTGEDT-GITNDLGIVYG--NSPFILAFASNE +TDV--PAFEQTIR---------- +>[subseq from] Beta-lactamase CARB-6 n=1 Tax=Bacteroidetes bacterium ADurb.BinA245 TaxID=1852818 RepID=A0A1V5GGH9_9BACT +-kQLQSKIEQAISGFQGEIGIYVKNLRTGKTV-NIHADTIFPTASIVKVPIMTGIVYKMN +KGELHYDSLFTYKDSLLYEGEDILGSFKSGEIALKKLLMLMLTTSDNTASLWLQTIAGGG +ANINRILDSLGFKDTRVNSRVPGREAFRAIYQWGQTTPKEMGQLFEMIYNRKLFSSDLCD +RMMRMLAKNYWDENEAISQIPPTIAVFSKNGCVNK-TRNEAMIVNAPKN-PYVFCIFTKN +NKTHENEAWTMARKVSKLLWGYf +>[subseq from] Beta-lactamase class A n=1 Tax=Nocardia puris TaxID=208602 RepID=A0A366DHT4_9NOCA +---TVDRIRAVFADAGCTGWLHARRCGTAADI-SVGGLDRVVTASVYKLVLLLAFCRRVD +AGLIDPRARLTVHPADCTPPTGIAALHDSVTVSRRDLATSMMTVSDNAAADILLGEI-GL +GAVEELLTELGLTETRIVGGTADVHRAYDPSYTSATTPEEMTRLLDLAWGGGVLSAEQTD +FVRSVMRKQVW-PHRIAAAFPRGVLVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLSAVDAAIAESARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. v-76 TaxID=1761769 RepID=A0A1C4EXZ5_9BACI +-------VRQWSSMYRGRVSYLFET--PEERI-EQGATNVYPSASTIKLLIAVEACRQID +SGVILVQQTIAVKQSDLVGGDGILHVYPYLPVTVKELVLLMLILSDNTATNMLIDLL-GQ +DRIQACINDLGLENTQLNRQMMDIQAS-AEGRDNVITAADLLTCLKVLYREDVLSKDSRD +FLKGSLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLFTHHKR-CYAVVLIDG +LE-HNEYGRRLIADLGRIIS--- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus sp. 143-6 TaxID=2485999 RepID=UPI000F79D69C +---------STIGQMSGVNSVYVSPADSSKTV--IENNQSQRSASSIKVFIMAAAYQMAE +AGTFDMSGVYTVQASDKVGGTGVLQSMANGTLTNQELIRHMIIDSDNMAANVIIDRLGGL +DAVNQEIEDLGATDTSLNRKLMDQD-ALNAGRDNMTSVKDLGMVMKRIYNQKLISKDADQ +NMLAILAQNNN-HTKLPAKLPATIKVYNKTGEYDYGVQNDAAVFETNKGA-LVVVVLSQD +GEHDEQ--LAT------------ +>[subseq from] serine hydrolase n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=UPI0009E91F7B +-rQLAERIARIDQQTPGRLGVYVKRLSDGSTM-NHGTEQAWYLASMAKVPVALAVLRQVQ +VGKAGLGDEMALQDGDRIDVGNIVWNDTGTRYSVRTLVERMLLESDNTAANMLIRSV-GE +DALNDGTRQMGTPNVTLTTFAQVRRDRYYRRNLNTATLQAYGGMLERLVRGQLLPEEPRT +VLYKAMKRDIYTGYRLQAGLPRDMPFIHKTGTQHR-RACHAGVLNPDDLQKALVIVACTA +DLDEQKQAGPVLESVGRAIR--- +>[subseq from] Beta-lactamase class A n=1 Tax=Aquisalimonas asiatica TaxID=406100 RepID=A0A1H8PZ54_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +----AFLDKIGAGASEADSLEEAFG-RYYETGLNSGPLTGFGAMLERLWEGELLNEDHTG +RLMAQMEQVTTGDRRIRAGLPDGTPYAQKTGTQIN-RACDVGIIHPEDPERTTIVAACAE +DYGDLRHAEEAFQALGRLLAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium faecium TaxID=34087 RepID=A0A2T5YB45_9SPHI +-tKLEQKLRALTQNFQGDIGIYVKNLKTQKSV-LIQADSIFPTASIVKIPILVGVFDKIE +KGELNLDQKFTYRSSQQYGGSGLMQFFKDSTTDLSTLVGLMISYSDNVTSIWNQQLAGGG +LVINELMDKLGLVNTKVNSRTEGRHDIWKKYGWGQTTPREMATLVEMIYQGKVVSLKASD +RMYRYLGNIFY-NERSLSQIPAYIKTASKTGSVDE-ARGEVVLVNAPSGD-YVFCVLTNN +IKTKHNEAEELTRKISHLLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Alcaligenaceae bacterium 429 TaxID=2562948 RepID=A0A4S1EAS8_9BURK +--QLESSLTPLLEKEPARISMAVRTLDGVSLF-DWHVQRAMPSASLIKVPMLLCLLEEVA +KGRVSLDDVRALPDSNRAGGTGILSQLPGVQLSLRELAHLMIVLSDNVATNALIDVL-GM +DRINQWCRQAGLAYTELQRHMMDAQAR-AQGKDNWTSAADACTTLLYLLQSPVLPEALRQ +EGLQMLADQRE-RGHFAAILPADVELAHKTGSLP-GLRHDAGIMTVGKR-SVVLAVLADG +FT-DARTSS-------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. 2BBP-J2 TaxID=2719381 RepID=UPI00142FD0B3 +----VARIHAALADAGVTGWLHALDVDSGEQL-DAGADQPVCTASVHKLCLLVTLHEQAA +RGALDLAEQVEAAPEGRTAPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTARLGLTRTRAVHTFGEMLAALDPARSNRSTPRDMTRLLGAVWRDEACTPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase TEM n=3 Tax=root TaxID=1 RepID=A0A0F6IVF0_BACTU +------------------------------------------------------------ +------------------------------------------------------------ +------MHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Serine hydrolase n=1 Tax=Pedobacter chitinilyticus TaxID=2233776 RepID=A0A443Z0N4_9SPHI +--KLNKRIGELVKGFNGEVGVYVKSLKTGKIA-TYNADTIFPTASMIKVPITCGVFDKIE +KGELAYNTQLIYKDSLLYAGEDILGSFKSGEIWLAKVLMLMITTSDNTASLWCQSLAGTG +TAINALMAKYGLEHTRVNSRTPDRQANQRKYGWGQTTPREMATLLTLIREGKMISEAASE +RIYRNLIRIYY-DKEALSEIPPYVQVASKSGAVN-ASRSEVVLVNAPHGD-YVFCIITKN +QKDTDNEAEVLIRKTSKMLWNYf +>[subseq from] Beta-lactamase class A n=1 Tax=Chloracidobacterium thermophilum (strain B) TaxID=981222 RepID=G2LLF7_CHLTF +---MMRRLQRRLAAFKGKVFCFAKNLDTGETF-GYNPDARVRTASTIKVPIMVEVFAQVA +EGRLRWDDKLTVVRRHEYEGGVLFELTPGTQITVRDAVRLMIVVSDNIATNILLDRI-TT +DAVNDRLAKMGFEHIRSLRKIAGGGEENKKYGIGVATPREMVRLLEGLERGTMVSPEASR +EMLAIMKRQQY-REGIGRRLR-GVEVANKPGALDH-LRSDIGIVYTKHG-RIAMAITVED +IPCSEAEGHLLIADI-------- +>[subseq from] serine hydrolase n=1 Tax=Chitinophaga rhizosphaerae TaxID=1864947 RepID=UPI000F80AF28 +-rKLTAQLLELTRSFNGDVGIYVQHLKTGRFA-AINADTVFPTASIVKVPLLVGLFDKID +KGELSYHQPMVYRDSAKYGGSGLMKLFKDSATEISVMAALMMSYSDNTTSLWIQSLAGGG +QRVNEILEQYGFKNTRVNSRTPGRADIWKIYGWGQTTPREMTRLVSMIRKGEILTPAACD +RMYRLMCRGYN-DESSLSQIPPYVQAAHKTGAVDD-ARGEVVLVNAPHGD-YVFQIATKN +IKDQDNEAVVLIRNVSAAIWRHf +>[subseq from] Beta-lactamase class A n=2 Tax=Thermomonosporaceae TaxID=2012 RepID=A0A2P6ULD3_9ACTN +-----ERIEAAFRDAGVTGYLHALDVDSGREI-GLRSDEPVVLASVFKVPLLVTFFRHVA +AGRLDPAAQVTLRPEDRCAPTGVSALQDEVRMSLRDLACMMITISDNAAADALFAAV-GL +DAIDATVAELGLRATRVVGTGRDLHEALDPMRTSRSTPREMARLMAMIWRDEAAPPAECA +QMRRFFGLQVW-PHRLSSGFPDDVRVSGKTGTLPT-IRNEIGVVEYPDGGRYAVAVFTRS +PLAVLPQADAVIGTSARLAVE-- +>[subseq from] Beta-lactamase, beta-lactamase n=1 Tax=uncultured Gemmatimonadetes bacterium Rifle_16ft_4_minimus_1650 TaxID=1665094 RepID=A0A0H4T164_9BACT +-dKLRADLEAIAEDFDGVLGAQIVDLTDSTTV-GVNQRLVFPQGSAIKIPILIEVFRQAE +RRPGMLQERRPVTRAAQVGGSGVIQYFGDGSLSLEDLAVLMITLSDNTATNVLIDAV-GM +NAINQTLADMGFRETRLQRKMIQPEAS-LRGEENLSTPAEAAEVMTRLARCDLVGQASCR +RITEILEIPKG--GAVREPVPGSVRIAFKPGTLE-GVATVWAYVELPDR-PYVVVVMTNY +GG----NGDEAIRMVSEVAYGYf +>[subseq from] Beta-lactamase class A n=1 Tax=Deinococcus hopiensis KR-140 TaxID=695939 RepID=A0A1W1V818_9DEIO +------------RGYAGTVGVLIQDLAGRELY-TLNPERVFPAASTIKVPLLILALQEAQ +AGRLDLQARVLLRAEDRVPGAGVLHELSPGLLTWGDVLTLMIVVSDNTATNLLIGQL-GV +DRVNAWLGDRGLAQTRLVGRLERQNEAQRQGERNRTSARDQVALLGALMRGELLDGAHTE +QAQSILSRQQL-RDLLGRNVPRDYRVASKSGELR-GVHHDVGVLFTP--HPLVVAVLSEG +GL--------------------- +>[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora sp. XMNu-373 TaxID=2650750 RepID=UPI0013908578 +--KLRSELNSIAAAQHGRWAFAVRE-GGGLVA-SVNGDEVMRAASTIKVALLILALQDVE +AGQCRLDSELDVPE-ERAGGSGVLKLMRSVRLPLREVLELMIGVSDNCATNIVVDLL-GL +DHISARINALGARSTRLERRLMDLEAA-RSGRDNVTTADDQALLLDLLTGTQLLSEDARR +LALDILGRQQF-NDRMPARLGPDIVCRHKTGELS-GVRHDVGILEFDGR-QVVLAALSSE +LADPTGVAADVIGAAAQAVV--- +>[subseq from] serine hydrolase n=1 Tax=Actinospica acidiphila TaxID=304899 RepID=UPI000A523293 +----VARIRAALTDAGVTGWLHALDIDSGEQL-DAGGDQPVCTASVHKLCLLVALHEQAE +RGALDLTEQVESVPEGRTAPTGMAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA +AIRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Rubrivirga marina TaxID=1196024 RepID=UPI000BA91544 +---LDAQVRQIAEDAGASVAVAVRDLETGEAA-TVDGDRPFHAASTMKVAVLAALLAAVA +DERHHLDDRLHVRNRFRSAGSPFRFAKRGRTMPLGTLAEHMIQTSSNLATNLLVDLL-GV +EAIREATARWGGAGVEVVRGVED-EAAYEAGIVNTATAYGLVGLFVGLEEGAGLPDEVRQ +FGLDVLFGQEF-ASGIPAGVPEGSRFAHKTGSIST-VQHDAGLVYLPDRRPYAVAILTEW +EADATNGRRETVASLSRAVYDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea pusilla TaxID=46177 RepID=A0A1H8F7I3_9ACTN +--------REIFDAAGARGFVHARDVDADAET-GLDPDEPVVLASVFKIPIALEYARQAA +AGELDRTERLTVTAADKDGGIGVSGCADDVSLTLRDLAHLMLTLSDNAATDVLLRRV-GL +ERVQATLAGLGLTRTRLIGGCAELFDVRDPERTTSATPRETTTLLSMIWRDEAGPAEACA +EVRAIMSRQVW-PHRLASGFGDEVKVSGKTGTLW-GVRNEAAVVEYPDGKRYAVAVFVRT +AAFRHPAADAAIGRAARVAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A522T9W0_9BACT +---LQSRLEAITRTYPGHVALYAKNLRTGAVV-AIDANRPVPTASVIKVSLMLEAFRQVK +AVRLSLAQPLTLTKANQVEGSGILRILTPGELSLRDTIALMMTLSDNTATNMVIDAV-GL +KPTNAFLAQIGMKNTYFYKKVFMPAAPQPADQKGKTTAREMGEMLERIYRCDLGNRSLCR +EMINIMRDQQD-REMIPRYLDDASPIADKVGELD-AVRNDVALVYTRSGQ-VVISMFTYN +NPTPDNKAELFIGRVAQTIVHAw +>[subseq from] Uncharacterized protein n=1 Tax=marine metagenome TaxID=408172 RepID=A0A381TNF1_9ZZZZ +-kQLETILKDKITSFDGVAGLAVKSLTGEKSI-SINGDEVFPTASTIKIPVLAKLFSLQE +EGEIDLSKRIRFTQDMYGAGSGVIHFLENDPFTVLDVAILMMLASDNTATNTCIDIA-GI +EGVNDLIRDMGLSKTKLRRKMMDPE-AINRGDENVSTPNELIMLMDHLHNRKP-TPKVSA +QVLGIMSKPKS--AYLNKAIGSKVVVANKPGGMDK-VRGDTGIVYLPNN-PYAVSIMSKF +SMVDSIAQEGFLIDLARTIH--- +>[subseq from] serine hydrolase n=1 Tax=Steroidobacter sp. SA29-B TaxID=2695856 RepID=UPI00132A551F +---LNHLLEAELSRWPAHTGLYVKHLGTGEQA-RIRAQEHFESASTIKVAIMVRAFQLAD +ENKLDLTSRHELTAGDYRGGSGILKYDLGLKLTLHDMITQMIITSDNTATDIMVAKVGGR +EKLNEFLREAGYKALKLNRTTHEFF----------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Steroidobacter sp. SA29-B TaxID=2695856 RepID=UPI00132A551F +------------------------------------------------------------ +------------------------------------------------------------ +-AFTEPYRELIAQVTTAEERARESRARHNDDETGVATPAEMGALLEGIERCTLATRQSCE +DMKRILRAQQV-THKIPHYLS--VPAGNKTGDTGS-VTNDVGIIYSLSG-PIVMASYNMD +IKAQRTELDDRIGALARRVVDYf +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012EE81F3 +------------------------------------------------------------ +----------------------------------------SMAYSDNTANNKIIKEIGGI +KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus similis DSM 23365 = JCM 2765 TaxID=1423804 RepID=A0A0R2FG50_9LACO +-------VNQTVGNIAGTNSVYVSPVNGQQNV--LTVNRSQSAASSIKLFILITAYAMEK +AGTINLNDSYTLTASDKVGGTGVIQNMADGTLTYRDILRHMIVDSDNTGANIMIDKLGGF +DPINAKIKSLGDTGTKLKRMMMDTD-ALDNGIDNMTSARDMGTTLKRLYNHQLVSKKADS +EMLSILVANND-HDKLPQNLPSTAKVYNKTGEYDYGIQNDAAIIENTHGA-FVVVVLSEN +GHRD--EQISAMNQLGEQLY--- +>[subseq from] serine hydrolase n=1 Tax=Clostridium symbiosum TaxID=1512 RepID=UPI000E539DB0 +---LKLNVLNLCSRIEGKKAIVIEDLKTGEAV-EINRDEVFPAASLIKVPVLSALFRMAK +ENHIALDERIELEKDSRIGGFGILKDLGDGLPAVRDLAVLMITLSDNIAANLLIDRI-GM +SQINSELQAMGMKHTVLQRKMMDSQAK-ERGLDNYTSAGDMQKLMKAILESSF-----RG +DILDILFRQQC-NNKLPALMEGGVRFAHKTGDLP-GVEHDAGIICTDDRE--IIAIVLTD +ELADNREGIWLNQEIGKLI---- +>[subseq from] Serine hydrolase n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A316Q2S9_9FIRM +----QKHLEELIKPLKGKIGFYYENMTDGGTL-TYNSSEVFTAASVIKVPLFMYIAKLVN +EGKLSWDQQVIVRDEDKKPSCGALLSLSGDIVDIESLCRLMITLSDNTATNMLIRAA-GM +ENLRKGFKDMGLSKTEIQRELFDDS-ASAAGLDNYICPEEIAMLLKEVYRREFVSPDISE +KIESVMLLQQI-RHKIPGYIGRKKKIANKTGEDSN-TTHDAAIVFAQ--KPFVLVITSND +TD--VAETERFIRQVALELY--- +>[subseq from] serine hydrolase n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000CC03A8D +-------------------------------------------------PILVALFEEVD +AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK +AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS +KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR +PFGD-KRAKSFINQVSRLVYSY- +>[subseq from] hypothetical protein n=1 Tax=unclassified Bacteroides TaxID=2646097 RepID=UPI000AF4D17E +----------------------------NDSIsGVNQNERFAMHSVMKFPQALYVADYLS +RKGLALDDTIVVDKADLMQWSPMLKRFEGKKFSYAELLELSLAQSDNNACELLFRHCGKP +KAVEKYMRKLGFYDIYVRITEEKMHKHSSKAIENSSTPAEIARLFEWFYHHKD-DNQYLT +FIWKTMADCSTGLKRIPAAIPAGAHIVHKTGTGFLQDMNDAGLIIMPDGSHAIIAVFTKQ +SP-----SEAVITDIARQL---- +>[subseq from] Uncharacterized protein n=2 Tax=Bacillus TaxID=1386 RepID=U5L843_9BACI +-nQLEKRLADILRQCPGNASLAVEY--GERAI-YMNSGRKYPAASLIKIPIMMEAFFQAE +EGVLDLSEQVCIGGIEKAGGAGIIQSLSVTALSILDCITLMIIVSDNTAANLLIKLL-GK +KNINDRMHGLGLQTTVLGRKMMDFEAA-AKGIDNFTTAADMVKCLRAIKDGELFSEKNRS +KMLDIMEAQQF-REKLPALACKELKIANKTGELP-GIEHDCAIFAS-GRDVLYAAVLIEG +LS-SPEEGNHAIRLIG------- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=UPI000CCC42CD +--EIEKRLGEIIGEAEGTWGVVVEELGGGQHF-SHMPDERFIAESVIKVPIMAAVYEAAD +NGQFSVSDQLTLRKEDLVGGSGFLYTLSPGLLTIRDLITMMIIQSDNTATNMLIDLV-GK +EQIEQTMRNLGMNQSRYSRKLMIYPV--DVTENNMITAGDVASMLGKIASGAFLSQRACE +EMIAIMDKQQV-VNGLPSLLPPEWKLPCKSGWDT-GRQHDVGVLIAAGRK-ITITALSKD +VQAS--AALRTLGLLGKAVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7Q176_9BACT +--TLRNRLEARIARAPAQVGVYYRSLVRPDSV-LIGANLRLHAASTMKVPVMIQIFRDAD +AALLGLDDSLTVHTASLVPGAAFTYALVGRNRSVRELLELMITRSSNLATNILIERV-SA +SRAQASARSLGAWSTQVLRGVEDGA-AYRAGLNNTTTARDLGVLLGAIAGGLAASRAACD +SMLAILGRQEF-NEGIPVGVPPGTRVAHKTGWIGEVVYHDAGVVYPADGASYVLVVLTGG +IKED-SVAHNLVADLSRLVY--- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus similis TaxID=414682 RepID=UPI00138EF77E +--------------------------------------RSQSAASSIKLFILITAYAMEK +AGTINLNDSYTLTASDKVGGTGVIQNMADGTLTYRDILRHMIVDSDNTGANIMIDKLGGF +DPINAKIKSLGDTGTKLKRMMMDTD-ALDNGIDNMTSARDMGTTLKRLYNHQLVSKKADS +EMLSILVANND-HDKLPQNLPSTAKVYNKTGEYDYGIQNDAAIIENTHGA-FVVVVLSEN +GHRD--EQISAMNQLGEQLY--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces uncialis TaxID=1048205 RepID=A0A1Q4V8M2_9ACTN +----RSRIRSVFTDAGVTGWMHALDLGDGAEV-AVAADTPVSTASVHKLCLAVTVQRFAD +EGRLDLDEQLESLPGDRTPGPTGLSMLSGPVMSVRDLLAMALTVSDNAAADLLIDRV-GL +DAVNDAMRALGLRRTVAVQTMRDLIAVLDPARANRSTPREMTRLLAALWRDEACSAGRAR +ELRAVLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-VRNEAGVVEYPDGGRYAVAVFTRS +ARARQPAADAAIGTAARLAVR-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces vinaceus TaxID=1960 RepID=UPI000A3A25EF +----VARIRAALTDAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHEQAA +RGALDLAEQVESVPEGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharomonospora xinjiangensis XJ-54 TaxID=882086 RepID=I0V623_9PSEU +------------ETTGVRAWVHARCLATGRQA-GYRAGERVVLASVVKVPLVLEFARQVA +AGQLDPTDRVRVTAGDRLGGTGTAGCSDDVELSLRDAAFLAMSLSDNSAADLLFDRV-GV +ENVQALMTELGLTSTRVVCPPRDVVRALDAKHTNASTPEDMTRLLELVWTDKAGRPESCA +AVRAWMAQQVN-WLRLGAAFPPEVSVEGKTGTLPC-VRNEIGVVTYPDGGRYAVAVFTRV +ASGRRPDIERAIGLTARAAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Cytophagia bacterium TaxID=2026730 RepID=A0A2E0H0N4_9BACT +--SLDIKIKKMLKSQEGTFAVAFKNLDDGSKI-LINENEEFHAASTMKTPVMIEVFKKHL +NGEVSLDDSILVKNESIVDGSIFKYKMIGKYISLRELVYDMITISSNFATNLVVDYI-GA +GSINNSMREIGANRINVLRGVGDLKA-FDLGLNNTITAKDLLIIYENLANGKIINKNLSE +EMVNILKNQKY-SDIIPKYLPKNLEVAHKDGWIT-GVRHDSGIIFLDNEKKYILILLSKN +LD-DEVKGADLLANVSLEIYNH- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces violens TaxID=66377 RepID=UPI0004BF5E39 +----ERTIREMFADAGVRGWLHVAELDRSAQV-TIDPDEAVPMGSVYKVPLMVAFCRLAD +AGELDPRERLTLEPPDRVAPTGISILRDAVTMSLRDLVVMMMSVSDNTAADALLRTV-GT +AAVDEVCRDLDMPDTRIHGGVAGTWDVYNPLSKAASTPADMARLLRAIWTGRAASPERCA +FMREVMGRQPW-RHRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELPDGSTYTAVVFTQA +ARADLPRADAVIGAAARTAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Deinococcus puniceus TaxID=1182568 RepID=A0A172TC09_9DEIO +-------------GFAGVVGVRVCDEAGQELF-SLNADRVFPAASTIKIPLLIMALQAAQ +RGEWALSERVTMEAADRVPGAGILHELGAGLLTWQDILTLMIVVSDNTATNLVIERL-GV +DAVNAWLNTAGFPLTRLVGKLDQRNEAQRRGERNRTTAQDQTELLGRLLRGDYLNSTHTD +LALSILSRQQY-RDLIGRRVPCGYRTASKSGELG-GVHHDVGVLWTP--RPLVLALLSEG +GL--------------------- +>[subseq from] TLA family class A extended-spectrum beta-lactamase (Fragment) n=1 Tax=Ignavibacteriales bacterium TaxID=2049428 RepID=A0A3N5QAM3_9BACT +------------------------------------------------------------ +----------------------------------------TVSHSDNNGCDILFRLIGGT +GKVEKYIQSLGIKDISISTTEEEMHKDWDTQFTNWSTPYAMGLLLMKFFKGEILSKNSQE +YLWEKMVNTTTGANRIIALLPEGTIVAHKTGSSSTAATNDAGIVKLSDGNYFAIVVFVSD +SKSNVKAREGIIAQISKAVWDYy +>[subseq from] Uncharacterized protein n=1 Tax=Dehalococcoidia bacterium TaxID=2026734 RepID=A0A2E3BQD9_9CHLR +-eQLENTLKDKITGFNGVAGLAVKSLTGEKSI-SINGDEVFPTASTIKIHVLAKLFSLQE +EGEIDLSARIRFTRNMYGAGSGVIHFLENDPFTVLDVAILMMLASDNTATNACIDIA-GM +EGVNDLIRDMGLSXTKLRRKMMDPE-AINXGDXNVSTPNELITMMDHLHNQKP-SPKVSA +QVLRIMSKPKS--AYLNKAIGSTVVVANKXGGMDK-VRGDTGIVYLPNN-PYAVSIMSKF +SMVDSIAQEGFLIDLARTIH--- +>[subseq from] Uncharacterized protein n=2 Tax=Mucilaginibacter polytrichastri TaxID=1302689 RepID=A0A1Q5ZSI8_9SPHI +-kKLTAKLQEAVSGFQGEYGIYVHHLKTGKTV-SLNADTIFPTASMIKTGIQCAVMDKIE +KGELQYNQKLVYRDSLLYAGEDILGSFKNGDIQLSKVAMLMITMSDNTASLWLQKLV-GG +EYINNWLAQNGFKVFRVNSRTPGRQEQQKQYGWGMSTPYEMCRLFTMIHEGKAVSEAASE +RMYRNLIRIYW-DENALSQIPPYVQAASKQGAVNQ-ARSETVLVNAPHGD-YVFSVMTNN +IKTPDNEADQMIKKISALLWNYy +>[subseq from] Serine hydrolase n=1 Tax=Sphaerisporangium sp. LHW63015 TaxID=2248750 RepID=A0A366LU32_9ACTN +------------RAAGVTGWLHAADIDTGAQV-GFGAHAAVPIASVFKLPLLVAFVRQAD +AGLLVPAERVAVPAAERVFPTGISAMLDDVTVTLRDLCYLMIAVSDNTAADVLLARV-GI +DAVNAMLDDLGLTATRVLHDCRETAAVLDPASTNRSTPAELTRLLAMVWRDEAASAESCA +FVRRLLGLQVW-PHRLSSGFPDDVSVSGKTGTLPT-LRAEAGVVEYPDGGRYAVAVFTRS +HALNQPRADAVIGTAARMAIDH- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. Marseille-P4200 TaxID=2040295 RepID=UPI000F6428A0 +------DLQSLINDLKGTCGLYIKDLQNNEEY-SFNKDVIFPSASIIKLFIMYKLFENLE +KGIMSLNDKITLKECYKVGGFGILKNLDENLLTLKDLVTLMITLSDNTATNMLIDLL-GM +ETINEDI----LSSTCLQRKMMDST-ALKKGLDNFTSPMDVCTVLEKILYTDSISETNKK +IMLDILKKQQC-NNKLPVNISNKLQLAHKTGDLP-GVEHDAGILFYKNQA-FIIVVLTKD +LEN-NTHGVQFNNKIGRLL---- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseorubens TaxID=66897 RepID=A0A656RI89_9ACTN +----VARIRAALTDAGVTGWLHALDIDSGEQL-DAGGDQPVCTASVHKLCLLVALHEQAE +RGALDLTEQVESVPEGRTAPTGMAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA +AIRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYALAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Nitrospirae bacterium TaxID=2026887 RepID=A0A533ZPN4_9BACT +----ERLIRHRLSALDARVGLHALHVPTGRQV-AVNADEPMNTASVIKIPIMILAYRDAE +AGSLHLDERYEVTLDNYRRGSGLIQTFTPGLPTIRDLVRQMIVTSDNIGTDIALGRV-GL +MRVNEMLTQFGYQQTRINKSTGDLVRREPAEWLGQSTAREMSRLLLQLLRGELASAATTE +EMLDILRGQFY-DSRLPRFIKEQALVAHKTGEAPPYVINDTGIIFHEGG-PTVVTVFVNQ +NQGTVLEVEEVIGQIAKDLVSAw +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A522PPI6_9BACT +-----RQLGAIASRFGGKVTFAAVDLKTGERY-GLAADQPVATASVIKLPVMVEAFFQIQ +EGKLQWSQPVKETDFDRVQGSGILQDLNPQILTLGDAITLMIDLSDNTATNMVIRTV-GI +EPVNVRMRMLGLRHTALNGYVDATNEEAKKFGLGVTTADDMVHLLTLIKQHEILTPAACD +QMLKILGKQRDIDARYTSGLP-GVTWEHKTGALD-AVRNDVGIADTPAG-PVVMAGFAFD +SPHQWTADNAVLGRLAQAALQHf +>[subseq from] serine hydrolase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=UPI0009E65255 +---LREEMMGIVQECSGKVSFSVLL--DDESL-SWEEDRRISSASLIKLPILMAAYEQIQ +TGRLRADAMIVLRHEDHVEGAGVLNGHDGLTLSIEDLLTLMITVSDNTATNRLIELI-GM +DSINRFCLDWNLKGTFLNRKMMDFPS-LEMGKDNWTSSEDVVSCLTLINEGPF-EESSRK +KMLTMLSRQQF-RDKLPALLGDDVKVFNKTGELP-GVEHDCAIIESASGKYAYVAVLTYE +LPAP-EEGRRVIRTMGKLIGD-- +>[subseq from] serine hydrolase n=1 Tax=Thermoactinospora rubra TaxID=1088767 RepID=UPI000A0FD5B2 +-------------------WLHAVDLDTGAEV-GHGADRPVVLASVFKLPLLVEFARQAD +AGALDWTEPVTVGPGERVFGPTGLSAMLDEALSLRDLAYLMIAVSDNTAADALLRRV-GL +DAVNAMLDRFGLERTRLVGGAADLFRVLDPARTSRGTPRECTRLLALIWRDQAASPERCA +WMRSVLGLQVW-PHRLASGFPDDVEVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +FSVNQPRADAVIGTAARMAVDH- +>[subseq from] serine hydrolase n=1 Tax=Nocardia puris TaxID=208602 RepID=UPI0011BEF108 +---TVDRIRAVFADAGCTGWLHARRCGTAADI-SVGGLDRVVTASVYKLVLLLAFCRRVD +AGLIDPRARLTVHPADCTPPTGIAALHDSVTVSRRDLATSMMTVSDNAAADILLGEI-GL +GAVEELLTELGLTETRIVGGTADVHRAYDPSYTSATTPEEMTRLLDLAWGGGVLSAEQTD +FVRSVMRKQVW-PHRIAAAFPRGVLVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLSAVDAAIAESARIAVT-- +>[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WL65_9BACT +-qTLDERINDAVKDFKGKVWIYAKNLDTQKTF-SLRGDERVRTASTIKLPIMVETYFQIS +EGKLKWTDEIILTKEKKVGGSGILGEFSDNTIDLRTAVNLMIVVSDNTATNLVLEKV-TS +DAVNARMESLGFNDTKSIRRIFGSEKIIKNFGLGMSSPKDMVGILEMLELGQLVNSEASK +SMLHVLKRQQY-KDGIGRNALDTVPVASKSGTLDR-LRADVGIVYTRRG-RIAMAITVDD +MQ--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Gelidibacter gilvus TaxID=59602 RepID=A0A4Q0XL62_9FLAO +-kNLEKGLQNLVKDFEGDVGIYVYNLKTNQEA-GVNADTIFPTASVVKVPILIEVFNQIK +AGKLHLKDTLVYDAKRKYGGSGLMQFYKDSTTDLRTLASLMITVSDNTTSLWCQELVGGG +MEINKTMADLGLAHTRVNSRTEGRTKDWETYGWGQTTPREMASLLVKMRNRTLVDAASSD +EMYRIMSNSYYTDYSL-SQIPPYVQTAAKQGMVNK-SRSELVMVNAPSGD-YVFYIATKN +NADEDNKAWQLQRAISAYLWQYf +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. CH32 TaxID=2530383 RepID=A0A4R4Y005_9ACTN +------DFESLFRRAGVTGWLYAADIDTGREV-GLDPDEPLPTASMYKVPLLVAFRRQVD +AGLLDPARRVTVPASDRLAGTGIAAMQDDVTISLRDLAYLMISVSDNTSADTLLELV-GC +DTINAMLDRFGLTGTRVVQSWREGSAVLDPARSNCATPRELATLFAMIWRDEAASAESCA +WMRGMLNLQVW-PHRLASGFPDDVAVSGKTGTLPT-LRAESGVVEYPDGGRYAVAVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=A0A385LC87_RHORH +-----------------------------AML-SVRGDERVVLASVYKLPLFLAFCAEVD +AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT +TAVEELLARLGLTRTRIIGGTADVYQAYDPAYTSATTPQEMTRLLEAVWSGSVLSPESTD +FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus pyridinivorans TaxID=103816 RepID=A0A419ZHV4_9NOCA +-----------------------------AML-SVRGDERVVLASVYKLPLFLAFCAEVD +AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT +TAVEELLARLGLTRTRIIGGTADVYQAYDPAYTSATTPEEMTRLLEAVWSGSVLSPESTA +FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Uncharacterized protein n=2 Tax=Bacillus TaxID=1386 RepID=A0A0Q3TF67_9BACI +-dELREKVYTEASRCKGRVGLIIEA--EDKRI-EINSEGRFSSASLIKVPILVECFRQSG +KGTLDLQQSIQIALVEKVGGAGVLQALSGNLLKIIDLMTLMIIVSDNLATNLLIDLL-GM +DQINQGMKELNLHQTELNRKMMDFT-ALNNGVDNYTTASDMLTCLKEICQNKILSNESAS +KAKEIMENQQF-NNKLSDQIDDIFKVANKTGELL-GIEHDCAIIQYENRN-VYAAVLIDQ +LTVP-KDGRQTLSSIGQLI---- +>[subseq from] Uncharacterized protein n=1 Tax=Deltaproteobacteria bacterium RIFOXYA12_FULL_61_11 TaxID=1797896 RepID=A0A1F9MHN9_9DELT +--QLQRRIALVSREFPGEVGLLVKDLTSGQVY-ATNAHTPFYLASTTKICVLVTLHHEIQ +LGRLTLEQKHVVQRDDFRDGSSAFEKLSPGSLSIAELQEMMMNDSDNAATDILYNLL-GA +ETINRVVRRLGFEQVGWITSMLEVRKRFYASSYNTATLWEIGRFLEAMYRGEILGREIDG +QMLALMRGCRTGKRRLEAGFPQGVLFAHKTGTQYR-CLCDLGIAELTDGPTLFLGAYVRG +YKETRTKAEEILARLGAAVIESf +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7M5V4_9BACT +---LRDRLEARISRAPAQVGLYYRNLAGSDSI-LIGANLRLHAASTMKVPVMIQIFRDAD +AGLLRLDDSLTVHTASLVGGGAFTYALVGRNRSVRELLELMITRSSNIATNILIERV-GA +SRAQASARALGAWSIQVLRGVEDGA-AYGAGLNNTTTARDLGVLLGAIATGRAASRGACD +SMLAILGRQEF-NEGIPVGVPPGTRVAHKTGWIGEVVYHDAALVYPSAGVGYVLVVLTGG +IKED-SVGHNLVADLSRLVYQ-- +>[subseq from] Serine hydrolase n=1 Tax=Streptosporangiaceae bacterium YIM 75507 TaxID=2339229 RepID=A0A3A4B918_9ACTN +------------REAGVTGQVHAVDVLGGRDL-GVGADEDAVLASVFKVPLLVAFARLAD +AGALDPRERVHVPAEGRSPPTGISAMLDPVDMSLRDLAFLMITVSDNTAADTLVGRV-GL +DAVNAAMRELGLRRTHVEHTGQDMYAVLDPAVTNRGTPREMTRLLELVWRDEAASPESCA +MIRRCMGLQVW-PHRLASGFPDDVMVSGKTGTLPT-IRNEIGVVEYPDGGTYAVAVFTRS +SSQTQPRADAVIGVAARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. 311R TaxID=1617904 RepID=UPI00067EC5A2 +--SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA +AGTLDPTEQATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLFERV-GL +DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVAVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=UPI00075144B3 +-----------------------------AML-SVRGDERVVLASVYKLPLFLAFCAEVD +AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT +TAVEELLTRLGLTRTRIVGGTADVYQAYDPAYTSATTPEEMTRLLEAVWSGSALSPESTA +FAQQVMRAQIW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea maritima TaxID=683260 RepID=A0A1G9RUQ0_9ACTN +------ELEEVFTSAGLRGLVHVREVDGDAEI-GLDPDEPVVLASVFKIAVALEYARQVA +AGELSRTERLTVTAADKDGGIGTSGCRDDVSLTLRDLAHFMLTMSDNAATDVLLRRV-GL +DRVNGTLAALGLRRTRLIGGCAELFDAVRDPARTTATPREITTLLAGIWRDEAGPPEACA +EVRRIMGEQIW-PHRLSAGFPDEVRVSGKTGSLW-GVRNEAGVVEYPDGRRYAVAVFVRS +EVERLPHADAAIARAARLAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A317ISL2_9BACT +-kELQKEIESLVQGFNGKVGIYVLNLKTGKVA-AFNADSIFPTASMVKIPILIGVMDKIS +KGELKYHDEIVYKDSLLYSGVDILGSFKSDEIELSKVMMLMLTMSDNTASLWLQSLAGNG +LRINQILDSLGFKITRVNSRTPGREEARNEYGWGQSSPREMVELMRKIYKGEIIDRNYSA +RMLRLLGRNYW-DEAGISQVPPDIFVASKNGAVDE-SRSETMFVAAPHE-PYIFSIMTNN +NKQPGNEAWVLTRKLSQLLWNKf +>[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00119DDEFD +------------------------------------------------------------ +------------------------------------------------------------ +--------HMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. E(2018) TaxID=2502239 RepID=UPI0010FA0C62 +--QNEQALLKLISSGEGTYGVSIYHFETKESF-EHHSDELFYSASIIKVPIMAAVFAHAA +EGKCSLSDKIPVREEDIVPGDGIIKHLSPGMWTIHDLIVLMIIESDNTATNVLIDLL-GI +DQINTYMKEWGFDQSHLHHKLQ-IKAAREPGKMNVLTAHEINEFLKKIALGSVVSLYSCK +KMIDILKQQKM-NDLLPSLLPPNWEFAHKTGYVS-------------------------- +----------------------- +>[subseq from] Serine hydrolase n=2 Tax=Saprospirales bacterium TaxID=2026790 RepID=A0A3C2EG45_9BACT +--------RALLSDDQGVFAVAYRDLDEPDRMvFINEHEVFHAASTMKTPVLYEVFRQAK +QGRFNIHDSIIVKNESIVDSSVFSKEKVGRKATIYELCFEMITKSSNLATNVIIDLV-GA +KNVTNAMREIGANDLQVLRGVEDLKA-FELGLSNTTTAIDLLVLFEALEKDKLPDPESSS +EILKILRSQFY-RDIIPRYLPREVVVANKTGSITQ-VMHDSGLVFLPDGRKYGLVLLSKK +WTDEA-KTREKMAQISKMIYESy +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. F-7 TaxID=573566 RepID=UPI000A8B1D83 +----VARIHAALADAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVTLHEQAA +RGALDLAEQVEAVPEGRTAPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTARLGLTRTRAVHTFGEMLAALDPARSNRSTPRDMTRLLGAVWRDEACTPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. BUPNP1 TaxID=1432786 RepID=A0A225TMR2_9NOCA +------------------------------ML-SVRGDERVVLASVYKLPLFLAFCAEVD +AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT +TAVEELLARLGLTRTRIIGGTADVYQAYDPAYTSATTPQEMTRLLEAVWSGSVLSPESTD +FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus formosus TaxID=54913 RepID=A0A4Y4I1T9_9BACL +--ELENRLSAIIRQAEGTWGVVVEEQGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE +QGHFRLDDQLVLRKEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK +AQIDQTMIDLGMRQSYYSRKLMIYPLD--IAENNKITAGDVASMLGHLATGSYLSQRACQ +EMIAIMKKQQV-RNGLPSQLPPGWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKN +VT--AQSALNTLGLLGRAVYDY- +>[subseq from] serine hydrolase n=1 Tax=Lentzea kentuckyensis TaxID=360086 RepID=UPI000A383D96 +--------TEVFAEAGAEGFVHAREIGTDHEF-SFGADDPVVLASVFKIPVAVAYAEEVA +AGRLDPAERTRVTSRYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDVLFHRV-GQ +AAVDKVLSNLGLHRTRILGCCEDLFAIVDPERTTSSTPREITTLLDAIWTDRAAVPEACE +RVRQIMTQQIW-PHRLSSGFPADVQVAAKTGTLPS-VRNEAGVVTYPDGRAYAVAVFTRA +KSLDQPAVDAVIGRAGRLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535GIF5_9CHLR +--------RALIERAPFRVGVFARSADADTLL-EHDPDQALPSASVIKVPLVMTLYADAA +DGRIDLERRMRLG--DRVDGSGVLRDLRDVALSLRDLAALTMILSDNTATNLVIDAV-GV +ERVAERLAEWGCRKTALRRRMYDFEAA-KRGLENVATARELASLLAILVEGRCRDRSTSD +AVLAVMERCAD-DTMLRRFLAPGTMVPSKSGTLD-ASRNDVAVFRGPERT-VLVAAFTSH +VE-DHLAAEHLLGILGR------ +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Sphingobacterium sp. TaxID=341027 RepID=A0A3D5A6N8_9SPHI +---LQQYINQIITGKNALVGVAISGISQNDTV-GVQASQRLPMQSVFKFPLAIVMLTEID +KGNFTLDQKIEITKRDLTPWSPIRDKYPDGVLTLREILEYTITLSDNIGCDVMLKLLGGP +QKVEQYFAKQGFKNISIKINEKTMQSNWDKQFLNWCTPQEMNNILKIFYVNNLLSMSMYD +FLWSTMKSTNTGL----------------------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535YL67_9CHLR +--------RALIERAPFRVGVFARSADAETLL-EHDPDQALPSASVIKVPLVMTLYADAA +DGRIDLERRMRLG--DRVDGSGVLRDLRDVALSLRDLAALTMILSDNTATNLVIDAV-GV +ERVAERLAEWGCRKTALRRRMYDFEAA-KRGLENVATARELASLLAILVEGRCRDRSTSD +AVLAVMERCAD-DTMLRRFLAPGTMVPSKSGTLD-ASRNDVAVFRGPERT-VLVAAFTSH +VE-DHLAAEHLLGILGR------ +>[subseq from] hypothetical protein n=1 Tax=Vaginisenegalia massiliensis TaxID=2058294 RepID=UPI000F549A64 +------------------------------------GDQAIRSASVIKLFILADLFKQAE +KGEVKLDQVYKLKAEDKVGGTGIQNAAPGTTFTYRVLATEMITNSDNTAANILINQLGGI +EEINRYIQSLGFTQSKMERKMLDTQ-ALNAGKDNYLSAKEVGEFLEKLYTKQLVSPQADQ +AMLDILLLQID-HGKLTNQLPSGTPIYSKSGQFEYGVVNDAAIIETDKGA-YIMVVLSQD +GNYDA--KVSSLQQLGKAIHEAf +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga eiseniae TaxID=634771 RepID=A0A1T4SZQ0_9BACT +--RLQQDLQQIVAKFQGTAGVYVQQLQTGAWA-AINADTLFPTASIVKIPLLVGLFDKLE +KGELGYHQTLIYRNSAKIGGSGLMQFFKDSSTEVSILAALMMAYSDNTTSLWNQQLAGGG +AAVNVLLEKYGLKDTRVNSRTPGREENRKIYGWGQTTPREMATLLAKIFRGEVISRASSE +RMYRLMTKGYY-DEQALTQIPPYVQAAAKTGSVNE-SRSEVVLVNAPHGD-YVFYIGTKN +IKDQENEAVNMIREISALLWKHf +>[subseq from] serine hydrolase n=1 Tax=Sphingobacterium sp. SGR-19 TaxID=2710886 RepID=UPI0013ECF5DA +--RLERMLKNEIKDFQGDVGIFVQHFKKNRTV-SIQADTIFPTASVVKVPILVGVFDKIN +HGKLKLNDSYIYDAKRIYGGSGLMQFYKDSATNLSTMVSLMLTYSDNVTSIWCQELAGGG +IAINQLMDELGLPNTKVNSRTEGRQKIWEKYGWGQTTPREIVKLMTMIEAGKVISPRLSD +KMYRYLKNQYYNG-EALSQLPAHIATASKTGALNQ-TRNEVVFVHAPSGD-FVFAILTKN +NKDQDNEAEVLIRKISNILWNYf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8SEH7_9BACT +---LDRRVRDEAAKFEGTVSLYAKNLDTGAEY-SFGGDERVRTASTIKIAIMIEAFSRVA +EGRAKWTDELVLTKEKKVSGSGILPEFSDGLLTLRDAVTLMMLMSDNTATNLVIDALGGA +DTVNARMQSLGMTDTRLMRKVGGGGESEEGKKEGRTSPHEMVMLVEKWERGEIVSPSVSK +EMIEFMKREQVQDGIWRELWK--TPRATKSGALD-ALRSNVGIIYHTRG-RIALAVTCDD +MPEPN------------------ +>[subseq from] Uncharacterized protein n=1 Tax=Xenorhabdus ishibashii TaxID=1034471 RepID=A0A2D0KA77_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +---TRFARTIGDNFFRLDRHEPELNTAIPGDERDTSTPQAMAKSLYNLVLGDALVKTQRE +QLAEWIKGNTTGGASIRAGVPKDWIVGDKTGRCDYGTTNDIAVIWPPNRAPLVLVAYFTQ +PDKEAGSRPDVLAAAARIVTQ-- +>[subseq from] serine hydrolase n=1 Tax=Aminipila sp. CBA3637 TaxID=2697030 RepID=UPI0013678351 +-----------INTIPGHIGFYYKNMVTDECI-SFNENHHYIPASVIKLPIVMEIFRLSA +KGKVSLDSKLLVKDEDKMPSCGALNSFTGELVDIRTLCNLMITISDNTATNVLISYF-GT +DTLNEGFQSIGLTETRVNRRLFDAEA-SEKGIQNVITPAEIGMLLERLYRNEFVNQQVSE +DIKEILFRQQI-KHKIKELLPVGTKVGSKTGDDDN-ISNDVGIVYAK--QPFVVCFISNE +T---------------------- +>[subseq from] serine hydrolase n=1 Tax=Atopobium vaginae TaxID=82135 RepID=UPI00065DEEEF +-kELQQQIEELTQPYGSSVSVCIIDASNGNYC-HVNSDKAFVSASMIKLAVLCEYMHAVD +NGQLDPADRVTLKNMKVVGGTGLIQTERHASYSYDELCRYMIMYSDNTATNVLINKL-GQ +DAINERVQALVCKNTSLNRQLMALNTN----TENWISARDAATILYKFKNGTAASSTICA +KALEYLSKQTD-NEGMAEGISSG-AFAHKTGSLRS-MRHDGGIVL--GKRPYVIVALCDI +GAGN---ANRLMKEIAQKA---- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535I8I0_9CHLR +--------RALIERAPFRVGVFARSADAETLL-EHDPDQALPSASVIKVPLVMTLYADAA +DGRIDLERRMRLG--DRVDGSGVLRDLRDVALSLRDLAALTMILSDNTATNLVIDAV-GV +ERVAERLVEWGCRKTALRRRMYDFEAA-KRGLENVATARELASLLAILVEGRCRDRSTSD +AVLAVMERCAD-DTMLRRFLAPGTMVPSKSGTLD-ASRNDVAVIRGPERT-VLVAAFTSH +VE-DHLAAEHLLGILGR------ +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A2Z6A9V3_SHISO +------------------------------------------------------------ +-------------------------------------------MSDNTDANLLLRTIGGP +KELTAFLHNMGDHVTRLDRWEPELNEAIRSDARDTTMPAEMATTLRKLLTGELLTLDSRQ +QLRGWTEADKVAGPLLRSARPAAWFIADKSGAGERGSRGTIAALGPDGKPSRIVGIYTTG +SQAT------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. Z38 TaxID=2682780 RepID=UPI0012EA58FD +----VARIHAALTDAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHEQAA +RGALDLAEQVESVPEGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +EAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACAPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Rhodothermus marinus TaxID=29549 RepID=UPI001374DA27 +-------FGRIEHRYELTLGVAAYNLTTGASV-FYRADTLFPTASVIKLAVLVELYRQYE +QGYLSPQDTVVLTAGRIYPGSGVLQHLSVPRLSLQDAAVLMIILSDNTATNLVFDRL-GP +DSVNATLRSLGLQRTRMLNKPFGFSTNTPEARRGMGTPRELMQLMIAMARDRVVSAEASR +EMIEILKRQQW-TEMAPRLLPDTLQVAHKTGAIST-ARCDVGLIFSPRD-TIAFAVMTDH +IKDPDQVGNLAVAEAARLVYE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Nocardia tenerifensis TaxID=228006 RepID=A0A318KF22_9NOCA +--------------------------ETAAEI-CVDGHARVVTASVYKLPLFVAFCRFVD +AGRIDPTARLTVHPADCTPPTGLAALRDPVTLSRRDLAQSMMTVSDNAAADVLLGEV-GL +AAVDELLTELGLTETRVVGGTADMHDAYDPSYASATTPEEMTHFLRAVWTGAVLSSEQTE +YVKTVMRHQVW-PHRIAAAFPHGVSVAGKTGTIGV-IRNEVAVVEFPGEHPVAVAVFTRA +ARPHLPVVDAAIAEAARIAVT-- +>[subseq from] Uncharacterized protein n=1 Tax=Rhodothermus marinus TaxID=29549 RepID=A0A5S9CAP4_RHOMR +-------FGRIEHRYELTLGVAAYNLTTGASV-FYRADTLFPTASVIKLAVLVELYRQYE +QGYLSPQDTVVLTAGRIYPGSGVLQHLSVPRLSLQDAAVLMIILSDNTATNLVFDRL-GP +DSVNATLRSLGLQRTRMLNKPFGFSTNTPEARRGMGTPRELMQLMIAMARDRVVSAEASR +EMIEILKRQQW-TEMAPRLLPDTLQVAHKTGAIST-ARCDVGLIFSPRD-TIAFAVMTDH +IKDPDQVGNLAVAEAARLVYE-- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7V6A9_9BACT +--SLASRVSERLKRCDAVMGVAAKSLASGEAV-LVDADRRFPTASAIKTAVMVEVFHQIA +EGRFDRDKEVVLTREEKVDGSGVLQDHAGLRLTVGDLLSLMISVSDNTATNLLVGLV-GT +ASVDRRLEGYGLVDTKLFRPTRDGKADHPELERGMSTPRELVRLMELIAEGRVVSRAACD +EMLALLRAQQF-RTMIPRRLPEGIKVGDKPGWDERHVRIDAGVVETPRT-RYVIAICARQ +VRDTDNDALVTGADVARLIHDHf +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Staphylococcus epidermidis (strain ATCC 12228) TaxID=176280 RepID=A0A6A1YIN1_STAES +------------------------------------------------------------ +------------NKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI +KKVKQHLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN +FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDV------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Saccharopolyspora sp. ASAGF58 TaxID=2719023 RepID=UPI00144010C0 +------------DGLPGRAGFAAWDLDEQEPV-LVDAERVVHAASTIKVLIMIAALRAVQ +DGRIELDEYVELPA-ERVGGFGILRELPSVTISLRDLITLMIVISDNAATNAVIDAV-GF +EAIRDCAADLGCTATRVERRLMDPNAH----GRNETTALDQARVLDALARGTALPPELTE +HALEVLSKQQV-RDRLPALLPDGAQCWNKTGELL-GLRHDVGLIGA-DRPRAVVAVLVDE +LTDER------------------ +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. HNS054 TaxID=1662446 RepID=UPI000ABD66A5 +----VARIHAALTDAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHEQAA +RGALDLAEQVESVPEGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +QAVNATTERLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACAPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. 7K502 TaxID=2530387 RepID=A0A4R4Z1H9_9PSEU +-------------GLPGRIGFAAWDLDEREPV-LVDAERVVHAASTIKVLIMITALRAVH +EGRLGLDAEVELPAE-RAGGFGVLRELPSVTISLRDLITLMIVISDNAATNAVIDAV-GF +EAIRACAADLGCTATRVQRRLMDVNAP----GRNETTALDQARVLAALAEGSALPPELTE +HALDVLSRQQV-RDRLPALLPDGAQCWNKTGELL-GLRHDVGLIGD-ARPRAVVAVLVDE +LTDER------------------ +>[subseq from] serine hydrolase n=1 Tax=Actinospica acidiphila TaxID=304899 RepID=UPI000D6166AC +----VARIHAAFTDAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHERAA +RGALDLAEQVESVPEGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI000FECF340 +------------------------------------------------------------ +-------------------------------MTLKDLIKASMLQSDNTANNKIMEELGGV +KGFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQINDGNLD +LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ +DDKDGQPDDKVIADATEEAI--- +>[subseq from] Beta-lactamase n=1 Tax=Lentzea aerocolonigenes TaxID=68170 RepID=A0A0F0H6W5_LENAE +-------IADVFAEAGAEGFVHAREIGTDNEF-CHHADDPVVLASVFKIPVAVAYAEEVA +AGRLVETERTKVTSQYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDVIFHRI-GQ +EAVDKVLKNLDLHRTRIMGCCEDLFAIVDPERTTSSTPREITTLLEAIWTDRAAAPEACE +QVRRIMAQQIW-PHRLSSGFPADVQVAAKTGTLPS-VRNEAGVVTYPDGRSYAVAVFTRA +KALDQPAVDAVIGRAGRLAVDH- +>[subseq from] Putative beta-lactamase n=1 Tax=Symbiobacterium thermophilum (strain T / IAM 14863) TaxID=292459 RepID=Q67QS8_SYMTH +---LEEALHAYVSALSGTYGVAVVDLSTGATV-SVGGDQVFVAASTFKVPLAMYVFSLVE +RGEADLAEPLYYAPEDWEGGSGILHGSIAGDYTVAELVHLSLTVSDNIATNMLLRRF-GE +QNVFAYMRELGGTVTNLSTGR------------RATTPRDMALYMEVAYRRAAGDDGGYR +TLLGLLTQTAF-SDRIAAGAPSGVSVAHKIGTLP-AMVHDVGIVFLQDR-PFAIALFSSG +VNES--VAAASLADITRLV---- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E7G4T3_9CHLR +-----QDIDLIIKDVPAVVGVAARHIQSGKSF-FNKADEVFFTASTLKIPVIFELYRQVD +KGIVNPMQRIIVEDYDKSPGSGVLKDLTEGIPTIYDLATLMIIISDNTATDIIYKII-GK +DNIHSTLLNLNLKNTFIPMTCKELLYALAEDKSDVSSPNDMIKLMEIIYEKKILTEKSSN +IILDIMYRQQS-KTIIPYFLAPDIKTFHKTGGVTS-VRCDVGIVNGKSG-PYSIAIMAKD +VQ-DHKNIDLYLAKISEALYNFf +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus rhodochrous J3 TaxID=903528 RepID=A0A1X7KE32_RHORH +-----------------------------AML-SVRGDERVVLASVYKLPLFLAFCAEVD +AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT +TAVEELLTRLGLTRTRIVGGTADVYQAYDPAYTSATTPEEMTRLLEAVWSGSALSPESTA +FAQQVMRAQIW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA +ARADLPVVDAAIGEAARIAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinomadura umbrina TaxID=111806 RepID=A0A3D9SJ00_9ACTN +-qRVRARIEEAFRDAGVTGRLAAVDVDGGRGI-GVRPDEPVVLASVMKVPLLVALHRQAA +AGTLDPAERVVLGPDDRTAGSTGLAMLRDEVMSLRDLAALMITVSDNAAADALFARV-GV +PAVNTVLAELGLRGTHVAGTCRELFDALDPARTSRSTPAETAGLFAAIWRDEVAPAAHCA +QMRRLFALQVW-PHRLASGFPDDVRVSGKTGTLPT-IRNEAGVVEYPDGGRYAVAVFTRS +VSAVLPKADAVIGTAARLAVEY- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. ETH9427 TaxID=2211357 RepID=UPI000E0BE34B +----VARIHAALTDAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHEQAA +RGALDLAEQVESVPEGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +EAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACAPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Asinibacterium sp. OR43 TaxID=1076522 RepID=UPI00047DE39C +-qHLQQQITQLIAGFHGDIGIYVHDLKKNRTI-AINADTVFPTASMVKVPILTGIMDKIH +RKELDYHQVLIYKDSLLYEGVDILGSFKNNEIELSKVMMLMLTMSDNTASLWLQTLAGKG +TRINELMDSLGLKVTRVNSRTPGREANRNMYGWGQSSPREMASLMEMIVKKQVISDSSSQ +MMLRLLGRNYW-DENAISQIPSDAFVASKSGAVD-ATRNEVLFVNGKKC-SYVFCICTKN +NKESTNEAWVLTRKLSKLLWEYy +>[subseq from] Beta-lactamase n=1 Tax=Deinococcus sp. RL TaxID=1489678 RepID=A0A072N862_9DEIO +------------RGYGGEVGLLVTDLAGTELF-ALNADRSFPAASTIKVPLLVQALEEAQ +AGRLDLGARVCLQAEDRVPGSGVLHELDPGLLSWRDILTLMVVVSDNTATNLLLGRL-GL +GGANAWLRERGLSGTCLQQPPERQNAAQRRGERNRTTPRDQVRLLGQLARGELLDAPHTE +LALSILARQQF-RDLLGRHVPRDYRVASKSGELR-GVHHDVGLLLTP--RPLVVALLSEG +GTD-------------------- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522R9Q1_9BACT +-kKLTKELEKTVAGFHGTIGVYVWNLKNGKGA-SINADTLFPTASTIKVPIMCALFDKIV +KEELSYHQPLLYRDSAAYGGSGIMQYFKDSTIDLSVAATLMITRSDNTAALWCQSLAGGG +TVINQWLADHGFQNTRDNSRTPGRQKIWEIYGWGQTTPKEIANLVVDIREAKVLDSAACE +RMYRNMTHQYW-DDIALSQIPPYVQTASKGGAVDD-ARSEVVLVNAPHGD-YVFAVYTKN +NKTPNNEAEVMIRKISALLWHYf +>[subseq from] Uncharacterized protein n=1 Tax=Lactobacillus rapi TaxID=481723 RepID=A0A512PPS0_9LACO +--KVTKAVRATVQQASGTTAVYVATSKLAT---GVAVNRRQRSASVIKVFIMIEAMRRVK +AGTLNLKQEVAIPAHDQVGGTGVLAQRGTNQQTIGQLLELMIKVSDNTATNVLIDQLGGL +SKINRTIENLGCHHTKLQRKMLDYR-ALNAGHDNYTSAADLGRTLLKIDRHQLLGGRYDT +EMLRLLANNAN-QTKLPALISSKATIYNKTGEFDYGVQNDAAIVKKGQQ-SFVAVVLSES +GRQN--QQIKAMN---------- +>[subseq from] Uncharacterized protein n=1 Tax=Halovibrio variabilis TaxID=31910 RepID=A0A511UJE1_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +----ALARTLGVSTASFTQDYDHAFDAYEATGENVGALSAYGDLLASLHDGRDLDALQRE +RLLAMMQRTRSGQQRLKAGLGDGISFAHKTGTQQR-RSCDAGIAQRESAGPWVIVACARG +PAA-VSAHERALAGVGDAI---- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7W7Y6_9BACT +-------------------------------I-LRNERVTFHAASTMKVPVMFGVMQAVT +HGELRLDQPVRVKNDFVSIGSHYAYEMIGRELPLEELVRRMIDRSSNLATNIVIEFI-GA +PRIMELMKSIGANDIRVLRGVEDDK-AYHAGMNNTTTALDLMLIFRALGERTVISREASD +RMIEILLAQEH-NDGIPAGLPPGTRVAHKTGWIT-GITHDAGIVFRPDGSKYVLVVLTRG +FK-SEKQAKRVQARIARATW--- +>[subseq from] Serine hydrolase n=1 Tax=Flavisolibacter ginsenosidimutans TaxID=661481 RepID=A0A5B8ULM0_9BACT +-kKLQKQVEELIKGFNGDVGVYVKNLKNNKTV-AVNADTVFPTASMVKIPILLGIMDKIN +RGELAYHQPLQYKDSLLYAGVDILGSFKNDEIELSKVMMLSLTTSDNTASLWLQSLAGGG +LRINQILDSLGFVNTRVNSRTAGREAIRNVYGWGQTSPREMATLMEEIVKGEIISKERSA +QMLRLLGRNYW-DEEAISQIPSDVFVADKNGAVNE-SRSEVLFVNGH-GARYIFCICTKN +NKESNNEAWVLTRKLSKLLWEYf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004BF231F +-------LQDAFTEAGVTGRLHAVDIDSGAEV-GVGADQPVVTASVHKLCVLVTLHEQAA +AGRVDLTEQIECPPEGRTSGPTGLAAMLDPVMSLRDAAYLMMAVSDNTAAELLLDRV-GL +DAVNATTARLGLTRTRAVHSFREMFAALDPARTNHSTPRDMTRLLGAVWRDEACTPEHGA +AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA +ARATLPSADAVIGTAARIAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Stigmatella erecta TaxID=83460 RepID=A0A1I0L3L6_9DELT +---LNGLVETAARNFDGELSLYVLDVESGEEY-AYDADRLTYLSSAIKLGVMLEVMHQVD +AGRLSWDEPLAFTSDSLRDMHRLHRARPGDALPVSALLEYMMVDSDNAAADLLMKRV-GV +DAVKAQLATRGVQTGPVVSLLDERRRAFYAEQVNSASMRGMGQLLRQVARCEGLSAASCT +RAHTLMRACQTGRGRVAAGLPATAAWAHKTGTQHR-RACDLGFLTLPSGQPAVIAACTRN +FWR-VADAERLFAFLGESVWR-- +>[subseq from] Uncharacterized protein n=1 Tax=Halobacillus mangrovi TaxID=402384 RepID=A0A1W5ZZE8_9BACI +-dALQREVEHIVASVKGRVSVVIEN--KKAAI-AINGSERTTAASTIKIPIIMEAFRQAE +NGDLDLKEKVQVTPDLKTGGDGVLKLLENELLSILDLMKLMIVVSDNTASNLLITRL-GF +SNINHLCEQLGCTNTRLNLYFMDFRAR-GAGVDNMTSARDMVAFLSEIEGGNFVNERSRK +TIYNILREQQF-TSGLPAYNKEDILTANKPGMLP-GIQHDVGIFKYRNET-VYAAVLLSE +LN-DEEAGRRAITDIGRSIIK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter salegens TaxID=143223 RepID=A0A1M7NT09_9FLAO +--KLQQKLETIARDFKGDVGIYVKHLKSGKEA-AINADTIFPTASIVKIPILLKIFDKIE +KGELSYKDSLVYSKDRIYGGSGLMQFYKDSTTDLRTLVALMISYSDNVTSLWNQELAGGG +EGINELMAEIGLEHTRVNSRTEGRDKDWEKHGWGQTTPREMASILEQIRNRKLISAAASD +EMYRLLGNSFY-QDYALSQVPPHVQAAAKQGMVNK-SRSELFMVNAPSGD-YVCYIATKN +NEEENNEAWQLQKEISALLWNYf +>[subseq from] Uncharacterized protein n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A2W4R150_9FIRM +--DLTAILERMTRGLPGTIGIYVTDLITGRSA-GLSPMAEFYAASTIKVPIAMAVLWLVD +RGRLSLDQTIAYQPEDYEAGTGILQARPGDQVSVRRLLELMITVSDNIARNMLERFI-GS +GTIRNYMLSLGVAPA-YDPHE------------TPVTPYGMNQVLLALDSGRGLSPASTR +MLLRWMEEAVF-RRRIPRYLPESVVAATKIGSRDD-EFHDIGLVYAPDR-SFAISVFTKG +MT--EARAEEAIARIAEAVYW-- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus sp. RL TaxID=1489678 RepID=UPI0009DD64D7 +------------RGYGGEVGLLVTDLAGTELF-ALNADRSFPAASTIKVPLLVQALEEAQ +AGRLDLGARVCLQAEDRVPGSGVLHELDPGLLSWRDILTLMVVVSDNTATNLLLGRL-GL +GGANAWLRERGLSGTCLQQPPERQNAAQRRGERNRTTPRDQVRLLGQLARGELLDAPHTE +LALSILARQQF-RDLLGRHVPRDYRVASKSGELR-GVHHDVGLLLTP--RPLVVALLSEG +GTD-------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A4P5TDK2_9BACT +-eKLESKIKAEFKRSPGLFCLAFKEIGQPQNQlMIHADSIVHAASTMKTPVMVEIFNQIE +QKKWKLSDSILVKNESIVDGSPYKYQKIGGKTTLYQLIYDMITYSSNLATNILIEMA-DA +KKVTQKVREIGAKNMQVLRGVEDQK-AYDLGLNNQVTARDLMLIFEKLGEGKWISESSCI +QMIDILKQQHF-NELIPALLPKEVIVAHKTGWITK-HSHDSALIILPDGRKYALVILSKG +WE-SNDLATDILANSSKYVYDY- +>[subseq from] serine hydrolase n=1 Tax=Rhodothermaceae bacterium ISCAR-4553 TaxID=2558931 RepID=UPI00141E987E +---LQARLERLVEGFRGDAGVYVRHLPTGRYA-AIHADTLFPTASLIKVPILIKTFDAIE +RGELAYQQELVYRDSLRYPGVDLLGSFKDGEIALSKMVMLMLTMSDNTASLWLQHLCGTG +TAINAWLAAHGFEHTRVNSRTPGREAARERYGWGQTTPREIAELLVMIREGRAVSPAASE +EMYRTLTRTYW-DDEALSQLPPTVQAASKQGAVSR-SRSEVALVNAPHGD-YVFAVITKN +QEDTDNEGFVLLRDVSRLLWEHf +>[subseq from] Beta-lactamase class A n=1 Tax=Lentzea albida TaxID=65499 RepID=A0A1H9DTK9_9PSEU +---------------GVEGFVHAREIGGGREF-CHGADDRVVLASVFKIAVAVAFADEVA +AGRLDASERTRVTSRYRIGGIGTAGCADDVEMSWRDLASFMMTMSDNAATDVLFHRV-GQ +AAVDAVLTKAGLERTRILGCCEDLFAIVDPERTTSSTPREITTLLDAIWTDRAAAPQACE +EVREVMSRQVW-PHRLSSGFPSEVRVAAKTGTLPT-VRNEAGVVTYPDGRSYAVAVFTRS +SSPDDPAADAVIGRAGRLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus praedii TaxID=1742358 RepID=A0A4R1B101_9BACI +--ELKENVYTEASKCRGRVGLIIEA--EDKRI-EINSEGKFSSASLIKVPILIECFRQAD +RGTLNLQQPIQIASVEKSGGAGVLQALSSDLLKVMDVMTLMIIVSDNLATNLLIDLI-GM +DQINQGMRELNLQHTELNRKMMDFT-ALKNGLDNYTTASDMLTCLKEIGQNRILTKESAR +KARSIMENQQF-QNKLSDQIDDAFKIANKTGELF-GNEHDCAIIEYENK-SVYAAVLIDQ +LKVP-KDGRQTLASIGQLISQY- +>[subseq from] serine hydrolase n=1 Tax=Bacillus depressus TaxID=1602942 RepID=UPI00124C9D90 +--SLKAKVEEVAAKCQGRVGLVVET--SEGRL-EIRHHEKFSSASLIKIPILIEGLRQYD +HGLLHLQEYVPASPSSRVGGAGVIQTLSDDLLKVVDLMALMIIVSDNTATNLLIDRL-GK +DKINQCIQALYLQSTELNRKMMDFV-AIRNGRNNYTSPEDMITCLKVIDNQQFLSGASSV +KALTILENQQF-KNKLSYLMDDHIRVANKTGELP-GVEHDCAIIKYGGK-TIYAAVLIDQ +LSK-QEDGHKTLAQIGKLVSQY- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridium estertheticum subsp. estertheticum TaxID=1552 RepID=A0A1J0GFF8_9CLOT +----------YLSDAKLKYSIYIKELNQGKIC-EINQFKIVPSASIIKLFIMGSTLEKVS +TGTLSLKDRITINKKEKVPFSILTLLDDDNSYTINDLILLMIIQSDNTATNKLIDII-GF +GSINAFIKKHNFNSSTLQRKMMDNES-RLKGIDNLCNISDCALFLELIYNGKLINEEYSK +LMVSILTHQLD-DSMMKINLPTNITIAHKTGDLDF-SKHDVGIVYTSKT-DYIFSMFTWE +AI-SDNYAKNLIGNISQITYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E8X584_9CHLR +-qQLEDTLRTKIDAFNGVAGVSVKSFNSGNSI-SINGDEIFPTASTIKIHILAKLFHLEE +QGEIDLSKRIRFTRDKYGSGSGIIHFLENDPFTILDVAILMMLASDNTATNTCIDIA-GI +EDINDLIRDMGLSETKLRRKMMDPD-AINRGDENISTPNELVLMMDHLHNEKP-SPRVAS +QVLRIMSKPKS--AYLNKAIGPELTVANKPGGMDK-VRGDTGIIYLPNT-PYAVSIMSKF +SMVNSLSQEGFIIDLAQTVHA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudogracilibacillus auburnensis TaxID=1494959 RepID=A0A2V3VXY8_9BACI +-nELKERLEQLVKSEDGNWAIVVEDLDKQDSL-SINGKHQYYAASIIKLPIMATAFSMAD +QGLLCLSEKIKLKKVDVVGGAGVLQHSIGLELTFYDLLMLMIIQSDNTATNMVIDRL-GK +KQIQATMSQIGMLHSSFYNKLMTVPVQLEG--RNMITAHDVSTFYRTVVEGKFSSQYACE +QMIDLLKRQQI--QHLTAYFPPEWTFASKTGSVEN-LYHDTGVLYKRDRT-VIINVLSEG +CNQ--NKAIRMINQIGKEVYEY- +>[subseq from] serine hydrolase n=1 Tax=Bacillus praedii TaxID=1742358 RepID=UPI00070FB2ED +--ELKENVYTEASKCRGRVGLIIEA--EDKRI-EINSEGKFSSASLIKVPILIECFRQAD +RGTLNLQQPIQIASVEKAGGAGVLQALSSDLLKVMDVMTLMIIVSDNLATNLLIDLI-GM +DQINQGMRELNLQHTELNRKMMDFT-ALKNGLDNYTTASDMLTCLKEIGQNRILTKESAR +KARSIMENQQF-QNKLSDQIDDAFKIANKTGELF-GNEHDCAIIEYENK-SVYAAVLIDQ +LKVP-KDGRQTLASIGQLISQY- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus parabrevis TaxID=54914 RepID=A0A4Y3PTD6_BREPA +--ELEKRLSKIVQESAGTWGVVVKELAQGICF-EHQPDELFIAESVIKVPIMAAVYAACE +QGKARIEDQLPLRKEDLVGGSGFLYALSPGLLSIRDLVTLMIIQSDNTATNMLIDFV-GK +ELIDQTMRELGMERSYYSRKVMIYPQD--VTANNMITAGDVARMLEHIVSGSGFSRAART +EMIAIMNKQQV-LNGLPSQLPPGWELACKSGWDT-GRQHDVGILFVEGR-QFAIAALSQD +VTPE--AALHTLGLLGRAVYDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus rhodochrous J45 TaxID=935266 RepID=A0A562D6X8_RHORH +-----------------------------AML-SVRGDERVVLASVYKLPLFLAFCAEVD +AGRLDASGQLRIVPSDCTPPTGIASFRDPVAMSRRDVAASMMTVSDNAAADVLLGEI-GT +TAVEELLARLGLTRTRIIGGTADVYQAYDPAYTSATTPQEMTRLLEAVWSGSVLSPESTD +FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Uncharacterized protein n=1 Tax=Chitinophaga cymbidii TaxID=1096750 RepID=A0A512RGY9_9BACT +-rKLQKALQEIVDGFHGTAGVYVQNLKTGRYA-AVNADTIFPTASIVKVPILVGVFDKIE +KGELKYHQPLVYRDSAKYGGSGLMQFFKDSATELSVLLHLMMSYSDNTTSLWNQALAGGG +EQINRLMEQYGLQHTRVNSRTPGREEIWKIYGWGMTTPREMSSLVVKIFRGEVISPGASE +RMYRLMTKGYY-DETGISQLPPDVQVAAKSGSVNE-SRSEVLLVNAPHGD-YVFYVGTKN +IKEEDNEAVVMIRKISALLWRHf +>[subseq from] serine hydrolase n=1 Tax=Steroidobacter sp. YU21-B TaxID=2695855 RepID=UPI001325618F +---LNHLLEAELSRWPAHTGLYVKHLGTGEQA-RIRAQERFESASTIKVAIMVRAFQLAD +ENKLDLTSRHELTAGDYRGGSGILKYDLGLKLTLHDMITQMIITSDNTATDIMVAKVGGR +EKLNEFLREAGYKALKLNRTTHEFFRD---DETGVATPAEMGALLEGIERCTLATRQSCE +DMKRILRAQQV-THKIPHYLS--VPAGNKTGDTGS-VTNDVGIIYSLSG-PIVMASYNMD +IKGQRTELDDCIGALARRVVDYf +>[subseq from] Serine hydrolase n=1 Tax=Halomonas endophytica TaxID=2033802 RepID=A0A2N7U421_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +ERLDWFIRRLGLEALRLPTLEAAFD-AYYASDLNSGRLDSFGDLLAELGEGRALGAAASA +ELLSIMTRTTSGDRRLKSGFGSDVRFAHKTGTQHR-RTCDAGIASHGQGRKVVVVACVR- +GESNVVRSESVMAGIGRAM---- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Saccharomonospora sp. 31sw TaxID=2528243 RepID=A0A4P7C9S8_9PSEU +------------ETTGVRAWVHARCLATGRQA-GHGAGERVVLASVVKVPLVLEFARQVA +AGQLDPTDRVRVTAGDRLGGTGTAGCSDDVELSLRDAAFFAMSVSDNSAADLLFDRV-GV +ENVQALMTELGLTSTRVVCQPRDVVRALDPARTNASTPEDMTRLLELVWTDKAGRPESCA +AVRAWMGQQVN-WLRLGAAFPPEVSVAGKTGTLPC-VRNEIGVVTYPDGGRYAVAVFTRV +ASGRRPDIERAIGLTARAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus flexus TaxID=86664 RepID=UPI0009C2AFB5 +-----------------------------ERI-EQGATNVYPSASTIKLLIAVEACRQID +SGVILVQQTIAVKQSDLVGGDGILHVYPYLSVTVKELVLLMLILSDNTATNMLIDLL-GQ +DRIQACINDLGLENTQLNRQMMDAQAAVEG-RDNVITAADLLTCLKVLYREDVLSKDSRD +FLKGSLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLFTHHKR-CYAVVLIDG +LE-HNEYGRRLIADLGQIIS--- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Chloroflexi TaxID=167963 RepID=A0A5N9EQU3_9CHLR +--NLESTLDNIINQFEGVAGLSIRCLNNNKTI-SINGDDVFPTASSIKIHILTQLFTLED +KGTIDLAKRVRFTQDMYGAGSGVIHFLENEPFTILDIAILMMLVSDNTATNMCIDLA-GM +QETNNLIKDLGLSKTKLGRKMMDPD-AINRGEENISTPNELTKMMELLYQKKP-SPKVAN +NVLNIMSKPKS--AYLNKAIGPNTKIANKPGGMDK-VRCDVGIVYLPNN-PYAISIMSNY +GITDSLSQESFVIELAKTA---- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 112-3 TaxID=2486025 RepID=UPI000F78503B +---------------KGQNAV-FIQTTTGQTL-SWHNR-SQKAASDIKLFILATVYRQVA +AGKFDLAATYTLREADKVGGTGNLQAQAAGTVTNRDLLKDMMTVSDNTATNIIIREVGGL +AAVNQEIKRLGATQTVLRRKMMDQK-ALAAGRDNETSARDLGNLLMKIWRHQLISRAADT +AILKLMAANTN-HAKLPKLVPASRQIYNKTGEFDYGVENDAAIFAQGKQ-AVVVVALSQN +GEQQVPAMNQLGKQI-------- +>[subseq from] serine hydrolase n=1 Tax=Oceanobacillus sp. YIM 98839 TaxID=2663380 RepID=UPI0013DA98C9 +--ELEKSIENCFEDIQGEYSIVIEI--GNNQI-SLNGNKKMPAASIIKIPILMEGYRVIE +NKKFSEMTKIRYLEEDKVGGMGVLNSLASANLAWIDILTLMIIVSDNTAANLAIKNL-GF +SEVNRLCEEAGCKNTDLGRYFMDME-AIKKGSNNYTSANDMVFLLKEIVHGNLLSDDSKA +SILRILKHQQF-NTKLPGLLPGSLVMAHKTGELP-GVEHDVGILEYKEEK-VYIAVLLSD +LS-SNCDGQKAIAQIGELVYR-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. SGD-V-76 TaxID=1414648 RepID=A0A0V8JI71_9BACI +-----------------------------ERI-EQGATNVYPSASTIKLLIAVEACRQID +SGVILVQQTIAVKQSDLVGGDGILHVYPYLPVTVKELVLLMLILSDNTATNMLIDLL-GQ +DRIQACINDLGLENTQLNRQMMDIQAS-AEGRDNVITAADLLTCLKVLYREDVLSKDSRD +FLKGSLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLFTHHKR-CYAVVLIDG +LE-HNEYGRRLIADLGRIIS--- +>[subseq from] Uncharacterized protein n=1 Tax=Luteimonas sp. FCS-9 TaxID=1547516 RepID=A0A0H1AUM9_9GAMM +------------------------------------------------------------ +---------------------------------------------DNVAIVRLRNAEAGE +PRLQALARELGVPRSALKADTDAVFADYYRGERNQATLPAFATLLERLIAGELLSPESTA +LMLGHMRAIGTGDRRLSAGLPPGTDFAQKTGTQVR-RACNVGVIDPEARDGATIVLACAE +DFDALTQAEQAFQTLGRAL---- +>[subseq from] Abhydrolase_3 domain-containing protein n=2 Tax=Bacteroidales TaxID=171549 RepID=A0A255TFK0_9BACT +------------------------SIMNGELYcGHQEDSAFAMHSVMKFPQALYVADYLH +KKGLTLSDSVLVHKDSLDAWSPMLSIFEGMRFTFAELIEWSLKQSDNNACDLLFASCGQP +DAVEKYIHTLGFKDIHVQLTEKEMKKIPHRAIENSATPKEMARLLEWFYLHRD-DNKNLS +FIWDTMADCNTGQQRIAAVLPKDGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFFPK +SKEEKEVAEV------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea jiangxiensis TaxID=633440 RepID=A0A1G8F0J3_9ACTN +-------------RAGVTGWLYAADIESGREI-GHGADEPLPTASMFKVALLVEFCRQAD +AGLLDPACRVTVPGGAREAPTGIAVMLDDVTISLRDLAYLMIAVSDNSSADALLGRI-GF +DAVNAMLDALGLEVTRVTQSCETMNRALDPARTNRSTPREMARLFRLIWRDEAASPAMCA +WMRSVFKLQVW-PHRLASGFPDDVAVGGKTGTMPT-LRCESGVVEYPDGRSYAVAVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridium sp. BL8 TaxID=1354301 RepID=T0PHS3_9CLOT +-----DVISNCIKDFNINCAIVVKNLNTGEEV-KVNEQMAMPAASIIKLFVMGEVFNNIN +KGKIFLEDKITVKEEQKISYQLLTLFDEDREFTIRELLKLMICQSENTATNILIDMV-DI +DNINSFIKSLGFKNCEIQRKMLDMEAR-MQGKENYISAIEVSKFLELLYNGKIINEKCSK +QMIDIMKSQLL-VAEVHRYIPDNIGLALKTGDVW-GYKHAAGIFYIDNCD-YIFTMLINY +KDDEIKLMDEFMGKMSAAVYNYf +>[subseq from] Beta-lactamase class A n=2 Tax=Hydrobacter penzbergensis TaxID=1235997 RepID=A0A1H2VQJ5_9BACT +-qRLQQQVTQLLKGFNGDIGIYVHDLKRNRIV-SINADTVFPTASMVKVPILTGIMDKIH +RKELDYHQVLTYKDSLLYEGVDILGSFKNDEIELSKVMMLMLTMSDNTASLWLQTLAGKG +TRINELMDSLGLKVTRVNSRTPGREANRNMYGWGQSSPREMASLMEMIVKKQVISDSTSQ +MMLRLLGRNYW-DENAISQIPSDVFVASKSGAVD-ATRNEVLFVNGKKC-SYVFCICTKN +NKESTNEAWVLTRKLSKLLWEYy +>[subseq from] Beta-lactamase n=1 Tax=uncultured Clostridium sp. TaxID=59620 RepID=A0A1C6LDE1_9CLOT +-------------------------------------KVSFPSASTIKIFIAIEAFNQIN +KGVIFEDDIILLDGTMKVGGSGILSNYPNNSISIKKLIYLMMTQSDNTATNILIDIL-GM +NNINITINKILCKNSALNRKMMDFDS-IKRGIDNYTSASDLTIVLEKLYTNTCINKKYDT +LILNIMKDCAN-TSKIPKKLPSNITVSHKTGELDY-IENDVGIIFTPYGD-YILTILTQG +CNN--LDEIEAISELSKIIYDSy +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9T3Z7_9BACT +--SLRRELEQIRNHFPGDMSIYMKNLSTAEEI-ALDSDKVYETFSVIKLAIAAELMHQVE +SGKLSLSDRIITRAADERLPSGVLYALEPGLPTIKDLLTLMIITSDNEATDLLADKL-GR +AQVTAYMHALGLANTSIQFSDLDWDRYDAGIFFGHSTTKEIGRLLEMMASGKLVSKDASE +LILNIMEKQQV-NDRFPRYLK-DVRIAHKTGDGQPFIANDVGIIWVKDQ-PIVLVVFTGH +HRGG------------------- +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC333 TaxID=2070368 RepID=A0A2W2ECT0_9ACTN +----RPDFESLFRRAGVTGWLYAADIDTGREV-GLGPDEPLPTASMYKVPLLVAFRRQVD +AGLLDPAHRVTVPASDRLAGTGIAAMQDDVTISLRDLAYLMISVSDNTSADTLLELV-GC +DTINAMLDEFGLTGTRVVQSWREGSAVLDPARSNCATPRELATLFAMIWRDEVASAESCA +WMRGMLNLQVW-PHRLASGFPDDVAVSGKTGTLPT-LRAESGVVEYPDGGRYAVAVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium haloxyli TaxID=2100533 RepID=A0A2S9IUD8_9SPHI +-tKLERMLQDEIKDFRGDVGVFVQHFKNNKTV-AIHADTLFPTASVVKVPILIGVFDKIG +RGQLKLSDTYIYDANRIYGGSGLMQFYKDSSTNLSTMVSLMLTYSDNVASIWCQELAGGG +TTINQLMDELGLPNTKVNSRTAGRQEIWEKYGWGQTTPREIVQLMTMIRESRAITPRLSD +KMYRYLKNQYYNG-EALSQLPPHIATISKTGALNQ-TRNEVVFVHAPSGD-YAFAVLTKN +NDSPDNEAEVLIRKISYILWNYf +>[subseq from] Beta-lactamase class A n=2 Tax=Paenibacillus sp. 453mf TaxID=1761874 RepID=A0A1I6PNW9_9BACL +------------HQGGIRVTVSVVDLSGNVGF-LIGSEEQYKSASTIKLAIACALLQMVD +RGEICLEDQTVVRNEDVVGGSGSLQQEVMPLATIGRLARLMIAQSDNTATNVLIDVV-GF +ERVRALLEGLGIHRTQLGRKMFAPVHS--PELDNYADAQELTRLLKLVYQGELLSEYSRR +LLLIWMSKQEV-NTKFGAVLG-DMLIAHKTGEAGN-VTHDTGYFLIPGRE-LAVAVMTEV +MTEAQRIGNPVVQRIGKVIYDQ- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sulphureus TaxID=47758 RepID=UPI00037666F3 +----RTRIEAAFAEAGVTGWLHARDIDSGAQV-DAGADHSVVTASVHKLPLLVALHREAE +AGRLDLTERTHCPPTGRTPGPTGLAAMLDEALSLRDAAYLMVSVSDNTAADLLLERV-GL +DSVNAATRELGLTRTRALHTFAEFLAALDPRRSNHSTPRDMTRLLASVWRDEAANPAHCA +AMRRLLGLQVW-PHRMASGFPDDVHVAGKTGSAPT-LRNEVGVVEYPDGGRYAVAVFTRA +GSAALPAADAVIGTAARLAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Balneola sp. EhC07 TaxID=1849360 RepID=A0A1B6YAL1_9BACT +--ELKEKIDLELSTLEGDFAIAYRDINHPEQQiLINVDERFHAASTMKTPVLIELYKRAE +NTDLDLQDSILIKTESIVDGSPFSYRNLNKNTTFYKLAYEMITRSSNLATNILIDYL-DA +EKVTSTMRDLGADSINVLRGVEDLKA-YRQGLSNTTTARDLLVIFEHLSSDTLISEEANK +EMLGILKDQVY-NDMISAKLPEGTEVAHKTGWITN-VHHDSGIVFTGKDEGYILIFLSKN +AP-DRAAVLEAAANISSMIYNY- +>[subseq from] serine hydrolase n=1 Tax=Bacillus horikoshii TaxID=79883 RepID=UPI0009EE9918 +-qELRERVRTVVNSTAGHVSFMMED-EGGNQY-QIEADTHKKAASLIKIPILMAAFKQVE +AGRLKLTDRHLVEAESRVGGAGVISQLDAETFTLLDLLTLMIIVSDNAATNKVIDML-GM +DDVNEFCTKHGLSKTKLERKMMDFKAA-GQGLENRTCARDIVKCLKLLLENGVFTEENRL +QMLKILDGQQL-LDKLPFLMDDSVTIANKTGELP-GVEHDCGIVALGEK-KVLVAVLIDD +LT-DNAVGKKAIQEIGKIVEK-- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=UPI000E24816B +------------------------------------------------------------ +------------------------------------------TYSDNTANNKIIKEIGGI +KKGKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=UPI00132EC872 +-----------------------------AML-SVRGDERVVLASVYKLPLFLAFCAEVD +AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT +TAVEELLARLGLTRTRIIGGTADVYQAYDPAYTSATTPEEMTRLLEAVWSGSVLSPESTA +FAQQVMRAQIW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAIAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A0N0HLN7_9ACTN +--------------------VAELH-RPSARV-TIDPDERLPMGSVYKVPLMVAFCRLVD +AGLIDPGRRLTLAPDDRVPPTGISILHDPVTMSLRDLVVLMMTISDNTAADAVLRVV-GP +DVVDAMCGDLGMPDTHIHGGVVTTFSVYDPAFKASTTPADMARLLRAIWTGQAASDERCA +FMRDVMRRQPW-THRLASGFPDDVTVYGKTGSFGS-MRHEAGVVELADGSTYTAAVFTQA +ARAKLPRADAVIGAAARTAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Marinimicrobia bacterium CG1_02_48_14 TaxID=1805240 RepID=A0A1J4XK69_9BACT +----------------KRIAVAYRNLGTDEVK-AFMPLEDFHAASTMKTPVMFQLFKMRD +EGKLNLSDSVTVTNESILDGSGYTYLKLGRNVAIRDLIEKMITRSSNLATNILIEIA-DP +VKIAETMKQIDAFGVFVLRGVEDIK-AYEAGLSNRTTAGGMMNMMTAVYRSNRVADTSRQ +EMIDILAAQHF-NDMIPKGLPDGIKVAHKTGSITR-IAHDAAIVFPPNADPYVLVILTSG +YD-DNTEAQALGARISERIYAY- +>[subseq from] zinc_ribbon_2 domain-containing protein n=1 Tax=Enterococcus sp. 3H8_DIV0648 TaxID=1834178 RepID=A0A242DGR5_9ENTE +-------------KLQNKTGVFVSMIDEKNIDyEKSGTAPIRAASIIKLFLMEAFYREVN +EGTIRLDEPYVLKDTDKVSGTGVLQNYAEGTLTYEDLIRHMIVDSDNTAGNIVMNILGGP +ENITKFIYTQGFNDTRIERKFVDST-ALAAGKDNYTSAVDVGNLLKKIYQRKAVSPRYDQ +QMLEILKYNKN-HSKLPKEIDSEVNVYNKTGEYDYGVQNDACIFETNRN-AYVVVVLSED +GDESQ--QVSAMN---------- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga sp. CF418 TaxID=1855287 RepID=A0A1M7QYK3_9BACT +-rKLEKGLRELIKDFNGDIGIYVRNLKTGRYM-GINEDTIFPTASIVKIPILVGVFDKIE +KGELKYHQPFIYRDSIKYGGSGLMQFFKDSTTDLSVLLALMMSYSDNTTSLWNQALAGGG +QRINELMEQYGFSVTRVNSRTPGREGIRNIYGWGMTTPHEMAELVVKIRQGEIISKAASE +RMYRLMTHGYY-DETGLSQIPPYVQAAHKTGSVD-ASRSEVILVNAPHGD-YVFYAGTKN +NKTDENEAENLIRKISKYLWEYf +>[subseq from] serine hydrolase n=1 Tax=Sediminibacterium sp. WSJ-3 TaxID=2698829 RepID=UPI00137970AA +-kRLQRRLSEMFRDYPGSIGIYVHDLKKNKIV-AINADTVFPTASMVKIPILTGIMHKLE +SGELNYHQTLTYRDSLLYEGVDILGSFKNNEIELSKLMMLMLTMSDNTASLWLQSLAGTG +TRINELMDSLGMRYTRVNSRTPGRENNRAEYGWGQTTPLEMATLMEKIVRKEVINAAASE +KMLRLLGRNYW-DEVAVSAIPADAFVASKNGAVN-ATRNEVVFVNAKKS-RYLFCICTKN +NKEPGNAAWVLTRAVSALLWKYy +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E3DWL4_9CHLR +--NLESTLDNIINQFEGVAGLSIRCLNNNKTI-SINGDNIFPTASSIKIHILTQLFTLED +KGTIDLAKRVRFTQDMYGAGSGVIHFLENEPFTILDIAILMMLVSDNTATNMCIDLA-GM +QETNNLIKDLGLSKTKLGRKMMDPD-AINRGEENISTPNELTKMMELLYQKKP-SPKVAE +NVLNIMSKPKS--AYLNKAIGPHTKVANKPGGMDK-VRCDVGIVYLPNN-PYAISIMSNY +GITDSLSQESFVIELAKTA---- +>[subseq from] Beta-lactamase class A n=1 Tax=Allokutzneria albata TaxID=211114 RepID=A0A1G9T7F0_9PSEU +---VAAEVAERFADAGVTGWLHAREIDGTREV-SVGADTPVVLASVFKLPLLVAVFRAAE +TGEVDLAGRVTLDPGARSSPTGIGAMFDQVSMSVRDLALLAMSVSDNAAGDALVDLV-GF +EAINRVTESLGLTTTCVVQRSRELTEALRPESTNRSTPREMTALLAALWRDEAASPESCA +AMRRLLGLQVW-PHRLASGFPDDVRVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTAS +VRLTLPAADAVIGTAARVAVDH- +>[subseq from] Beta-lactamase n=1 Tax=Deinococcus maricopensis (strain DSM 21211 / LMG 22137 / NRRL B-23946 / LB-34) TaxID=709986 RepID=E8U6Q1_DEIML +------------RGFPGVAALVVEDLHRGERLvELQGARAFPAASTIKVPLLVHALQRVQ +AGALNLGARVPVPADARVPGAGVLHELDGGLPTVRDLLTLMIVVSDNTATNLVIDLL-GE +AAFNAWLQAEGLRGTHLVRPPHLQNPAQRRGERNRTCADDQVTLLSRLARGELLNPELTA +LALDVLSRQQV-RPILARHLPLSVRVASKSGELR-GVRHDVGVVWLP--RPLVVAVLSEG +GADAR------------------ +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7U5E7_9BACT +----------------ERLGIAFYDAETTLQW-SYNADAVFHAASTMKLAVLLAVFRQYT +RGELALDEPVHVRNKSIHDRRPYMYERLGRTMSVGRLAYHMITSSSNFAANLLVDVV-GV +PVIRTALAEMKIDGIKVLRGVEDQ-AAFDAGLNNEVTANGLLKLLRLVAEGMAYGEEASA +RMREILLDQRF-KSGIPAGLPPAARVAHKSGNIST-VHHDAGIVYLEGRRPYVLVVLTQF +PS--EAGLTTAVADVSRDIYE-- +>[subseq from] Beta-lactamase n=1 Tax=Leadbetterella byssophila (strain DSM 17132 / JCM 16389 / KACC 11308 / NBRC 106382 / 4M15) TaxID=649349 RepID=E4RZ75_LEAB4 +-qKLQRQIEQEIKGFRGEIGVYVKHLKSGKEV-RIQADTVFPTASLVKVPLLVGIFHQIH +DGKYNLDQEFIYDAKRVYGGSGLMQFYKDSATDLSTMISLMLTYSDNVTSLWIQELAGGG +IQVNQLMDHYGLKDTKVNSRTEGRAKIWEKYGWGQTTPKEMATLFTLIREGKIINKEQSV +KMYRYLKNQYY-NERSLSSLPPTVNTISKTGSVNQ-ARGEVVLVNAPHGD-IVFCILTKN +NETPLNEAEELTRRIAKLIWNFy +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000E0D41EF +---------------RSNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQVD +EGLLTLTSVIQRTEKNTVGGAGVLGALPQLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECARNIGLKKTVLNRYMMD-ETAVKQGVDNYTCASDVVECLREIYEGNFLKKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Caulobacter radicis TaxID=2172650 RepID=A0A2T9JJ87_9CAUL +----------AERARPGDLGVAVQDLTTAQRA-AVAGEHLFPLAGIWTAALGAAVLAEVD +AKALSLRETITIEDVDLSPPSGVADAWPSRRWTVEDLLKHAVADGDNTAADVLMKRIGGP +GAVTAWLDLKKVENLRVDRYARQLLSDYLADPHDSVTPLAAVRFLEALNQGELTSQENRR +RLLRMMEAAA--GERLRPALPAGARLAAITAATPTAADNVLAMVRLKDGRRFALAIFLKA +SPLEEADRDALMLEVMRTVMQ-- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A2W4NYY7_9BACT +-rDLNRSLQQLVSEFPGRVGIYVRHLKTGEEV-AINADTVFSTASMIKIPITIGIFDKIE +KGELKYDTVLTYRDSLASKGEDVLGSFKDGQISLAKVLMLMITVSDNTASIWSQEMAGGG +VTINAWLENNGFTHTRVNSRTPGREDAWKRYGWGQTTPREMANLVSMIRNNKVVSPRASE +RIYRNLVRIFW-DGSSLSQLPPYVQAASKTGSLDH-YRSEVVLVNAPHGD-YVFCVIADR +FETPDNAGNVLLRDVSRLLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC201 TaxID=1848320 RepID=A0A4R4NGV3_9ACTN +-------FDTLFSTAGVRGWLHAADIDSGREV-GHGADVPLPTASMFKVPLLVEFCRQAD +AGLLDPSDRVTVPAAGRSSPTGISAMLDEVTLSLRDLAYLMIAVSDNGSADVLLARV-GR +EAVNTMLAALGLHGTRVLQSCQEFNDALDPERTNRSTPREMSALFGMIWRDEAASAESCA +WMRAALNKQVW-PHRLASGFPDDVAVSGKTGTAPT-LRTESGVVEYPDGRRYAVAVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Deinococcus reticulitermitis TaxID=856736 RepID=A0A1H6U1V3_9DEIO +-----------ARGYAGTAGLVVLDLQTGETLyEEHADRPFPAASTIKVPLLVLALQAAE +RGELVLTGRVTLQAEDRVPGAGVLHELEPGLLSWRDVLTLMIVVSDNTATNLLIEQL-GL +EACNAGFRALGLRATRLVGPLERRNAAQRRGERNRTSAREQAGLLRQLGRGDLLGPEHTG +WAQDVLFRQQV-RPLIGRGVPADYRLASKSGELR-GVQHDVALLHTP--RPLAVALLSEG +GTDPREHP--------------- +>[subseq from] serine hydrolase n=1 Tax=Actinospica acidiphila TaxID=304899 RepID=UPI0013D40E95 +----VARIHAALTDAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHEQAA +RGALDLAEQVESVPEGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GM +EAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEAGAPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A3D4YK31_9BACT +--ALRRKLDSIADAHHGVVGYSVIDLETGARI-NRRGDETFPTASLIKVAILVTVYDLVA +KGQLSLDDPLTVLKIDQVPGSGVVQFHNGTVLTVHDAAWLMSTISDNTATNLLLDRI-II +RRVWAKMDSLGLQHTRVHSKSFLRNSSVAMDSSGVTTPNEMAHLFELMALGKAVNPAADS +AMLDILEHNTT-DFMLQRYLE-GARAAHKDGETD-AVRTECTLWYLRNR--VVACVMTKE +NKDQ------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces xiaopingdaonensis TaxID=1565415 RepID=UPI0002DE5CFD +----RTRIEAAFAEAGVTGWLHARDIDSGAQV-DAGADQSVVTASVHKLCLLVALHREAE +AGRLDLTERTRCPPTGRTPGPTGLAAMLDEALSLRDAAYLMVSVSDNTAADLLLARV-GL +DAVNATTRELGLTRTRALHTFAEFLAALDPRRSNHSTPREMTRLLASVWRDEAVDPAHCA +AMRRLLGLQVW-PHRMASGFPDDVHVAGKTGSAPT-LRNEVGVVEYPDGGRYAVAVFTRA +GSAALPAADAVIGTAARLAVE-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A3D5NZZ2_9BACT +----------------KRIAVAYRNLGTDEVK-AFMPLEDFHAASTMKTPVMFQLFKMRD +EGKLNLSDSVTVTNESILDGSGYTYLKLGRNVAIRDLIEKMITRSSNLATNILIEIA-DP +VKIAETMKQIDAFGVFVLRGVEDIK-AYEAGLSNRTTAGGMMNMMTAVYRSNRVADTSRQ +EMIDILAAQHF-NDMIPKGLPDGIKVAHKTGSITR-IAHDAAIVFPPNADPYVLVILTSG +YD-DNTEAQALGARISERIYAY- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium indicum TaxID=759821 RepID=A0A3E2NA19_9CLOT +------------EKLPGKISFLYENLETGERV-GYREDQPLMAASVIKLFVMASVFDQFE +KRKLKQDFSLPIYKKDCVPCGALTYLHEGICVTALDLVTLMIIFSDNTATNVLIDLL-GM +EEINRYIESLGFKNTRLNRKMYDVEKS-AQGIQNYITASETGRLLTMMHRGELVSEAASS +QMISILKNQQL-CSKIPFYLQEEPEIAHKTGEDR-GITHDVGIVYGK--VPFLV-CFCGN +ET-DTPAFERIMGELSLELY--- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus sp. 116-2 TaxID=2486004 RepID=UPI000F7A8037 +-------LSNNLAGIKGDTSAFYYNLNDNDSA-SYGDDEDQRAASDIKVYIMAAAYQKVD +DGEISLNDRYELTSEDKVGGTGVVQSQVGDSLTYRDLIDYMITKSDNTAANIITKEIGGL +DAVNDEIDELDLSNTKMERMLMDQD-ALSEGKDNMTTAHDLAMFMRKLYQHDVVSDKYDK +QMLSILSNTSN-HSKLPANINTNVDVYNKTGEYQYGVENDAAIFKRGNKA-FVLVVMSQN +GDSD--EQKDAMGSLGKEVTQ-- +>[subseq from] Serine hydrolase n=1 Tax=Rufibacter sp. R-22-1c-1 TaxID=2487040 RepID=A0A3M9MTQ2_9BACT +--KLTQKLQALTKDFQGEVGIYVKNLKTGRIV-AINADTLFPTASMIKVPIMVAMFDKIE +KGEIDPKTILRYRDSLYYAGEDIVGNFKDSSVALGKIQMLSITTSDNTGSLWLQQLAGGG +TAINVWLEKNGFTHTRMNSRTPGRRPNWEKYGWGQTTPREMASLVTMIRDGKAVSPAASE +RMYRNMGRIYF-DNEALSQIPPYVHTASKSGAVNQ-SRSEVVLVNAPHGD-YVFCIITKN +QKDENNAGYALIRAVSKTLWQHf +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. 6K102 TaxID=2530382 RepID=A0A4R5F255_9ACTN +-------FDTLFRTAGVSGWLHAADIDSGREI-GHGADAPLPTASMFKVPLLVEFCRQAD +AGLLDPSDRVTVPAAGRSSPTGISAMLDEVTLSLRDLAYLMIAVSDNGSADVLLARV-GR +EAVNTMLAALGLHGTRVLHSCQQFNDALDPERTNRSTPREMAALFGLIWRDEAASAESCA +WMRAALNKQVW-PHRLASGFPDDVAVSGKTGTAPT-LRTESGVVEYPDGRRYAVAVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga arvensicola TaxID=29529 RepID=A0A1I0S964_9BACT +-hKLEKGLKELIAGFNGDIGIYVRNLKTGRYA-AIHADSIFPTASIVKIPILVGIFDKME +RNELTYHQPLLYRDSIKYGGSGLMQFFKDSTTELSVLLALMMSYSDNTASIWNQSLAGGG +QRINELMAQYGLNVTRVNSRTPGRADIWKIYGWGMTTPREMAELVVKIRNGEVISKAASE +RMYRLMTHGYY-DEGALSRIPPYVQAAHKTGSVDE-SRSEVVLVNAPHGD-YVFYAGTKN +NKTDDNEAQVLIRNISAWLWNYf +>[subseq from] Beta-lactamase class A n=2 Tax=Lactobacillus silagincola TaxID=1714681 RepID=A0A1Z5J503_9LACO +---------RCIASASGQTSVYAVDLRNKQPVmVHNRSQ--RSASVIKLFIMVEAFRQIK +SGRLTLNQEVSIPKTDQVGGTGELAHQNVNQLSLIRLLTLMIRNSDNTATNVLIDRLGGL +NVINNEIKRLGCSDTQLQRKMLDYQS-LKNGKDNMTSVKDVGNLLVKLEQHSVLGDPYDA +EMLQLLRYNAN-QSKLPALINQKATVFNKTGEFDYGVQNDAAIVKKGNQ-VFVVVVLSQH +GNES--KQVGAMQQLGKQLYTI- +>[subseq from] serine hydrolase n=1 Tax=Chitinophagaceae bacterium YG09 TaxID=2608880 RepID=UPI00129BB497 +-kKLEHQLKQLVAGFRGDVGIYVLDAKKNKVA-AINADSVFPTASIVKIPIMIAVMDKIE +KGQLSYHQRLTYTDSLYYNGDDILASFKDSSIELSKVMMLMLTTSDNCASLWLQGLAGTG +SRINEILDSTGYTQTRVNSRTPGRQGNRAQYGWGQTSPREMVTIMSRIVNGSMLSPQASE +KMLRLLGRQYW-DEEAISQIPPGVFVADKNGAVD-ASRSEVMFVNGP--HPYTWAIFTKN +NQDTNNEAWVLTRKVSALLWNYy +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. ZS0098 TaxID=1904044 RepID=A0A421P563_9ACTN +----VARIHAALTDAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHEQAA +RGALDLAEQVESVPQGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACAPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Sphingobacterium TaxID=2609468 RepID=A0A077XRC7_SPHSM +--KLERKLRVLTQNFQGDIGIYVKNLKTQKSV-LIQADSIFPTASIVKVPILVGVFDKIE +KGELNLDQKFTYRSSQQYGGSGLMQFFKDSTTDLSTLVGLMISYSDNVTSIWNQQLAGGG +LVINELMDKLGLVNTKVNSRTVGRDDIWKKYGWGQTTPREMATLVEMIYQGKVISSKSSD +QMYRYLGNIFY-NERSLSQIPPYVKTASKTGSVDE-ARGEVVLVNAPSGD-YVFCVLTNN +IKTKHNEAEELTRKISHLLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536A0M4_9CHLR +----------ALASLPGEAAAFASDTYGHALF-CEREDELFPSASVIKLPLVMTLYADAA +RGRLDLDERVAVG--DRVDGSGVLRHMRDVELSLRDLAMLAVIVSDNTATNRLIERI-GV +DRVGERLREWGCPTSRLSRKMYDFEAA-KRGNENVMTARETVSLLVRLERGECEDRTTSD +AVLGILEQCQD-RTMLLRYLPYGTKVPHKTGTLDE-SRNDAAIV--PGERPVIVAAFTRK +LRD-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Lysobacter alkalisoli TaxID=2591633 RepID=A0A514BWP8_9GAMM +------------------------------------------------------------ +----------------------------------------------------------GE +ARLVALAKALGVPRDELDRDLDDVFGRYYETGRNSATLEAYALMLEKLVTGELLSEASTR +RILDHMRAITTGDRRIQAGLPSGTDFAQKTGTQV-ARACNVGVLDPDKGGGATVVVACAE +DFEDLAQAERAFREFGQAL---- +>[subseq from] serine hydrolase n=1 Tax=Anaerocolumna aminovalerica TaxID=1527 RepID=UPI000BE39D1C +-------------KDGAEISILVKDFKTQDILySHEDTKEVVSASIIKVPIMLTALEQVE +KGKLELDSFIELKDAGILEDTEVFE-YGGGKYTLEELLVWMIIESDNTATNCLIDLL-SM +ETINTFCKKHSLKSTKLERRMLDFQAV-QEGRNNYTSAGDMAILYEELYNRTILTPDLCN +TALGILKRQRH-KQLSLRYIYDDITVAHKTGSLDN-LDHDAGIFYLPNIQ-YYFGAFVWN +AP-SNEYASKWIGRISKGIYEYy +>[subseq from] Serine hydrolase n=1 Tax=bacterium BCRC 81129 TaxID=2487722 RepID=A0A4Z0J8L0_9BACT +-------------RLAGQNAVYIQ-TTAGQTL-SWH-DRSQKAASDIKLFILATVYRQVV +AGTFQLATPYTLREADKVGGTGNLQAQPAGTVTNQALLKAMMTVSDNTATNIIIREVGGR +AVVNREIQRLGATQTRLRRLMMDQK-ALAAGRDNVTSARDLGQLLMKLWHHQLISPTADT +AMLKLLAANTN-HTKLPANVPASRQVYNKTGEFDYGVENDAAIFAHGQRA-VVVVALSQH +GQEQIPAMNRLGQQV-------- +>[subseq from] Beta-lactamase n=61 Tax=root TaxID=1 RepID=A0A1U9XDT1_ECOLX +------------------------------------------------------------ +------------------------------------------------------------ +---------MGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. FJAT-25496 TaxID=1742359 RepID=A0A5B8Z0B3_9BACI +---LEKAMEKVAACCEGRIGFVLET--GNSRI-ERNSEVKFSSASLIKIPILIEGFRQND +RGLLDLQEEITVLPKDQVGGAGVLQALSADLIKIIDLMALMMVVSDNTATNLLIDRV-GK +NEINKCMKEIKLKWTELNRKMMDFE-AIKSGMDNWTTAHDMVTCLKIIDQQFFLSKESSQ +KAFSIMEKQQF-KKLFNTIDLEDLQVASKSGELP-GVEHDCAIIRYGDKT-IYSAVLIDQ +LK-DPYEGKQILSQIGKLILRH- +>[subseq from] serine hydrolase n=1 Tax=Bacillus flexus TaxID=86664 RepID=UPI0013CF7991 +-----------------------------ERI-EQGATNVYPSASTIKLLIAVEACRQID +SGVILVQQTIAVKQSDLVGGDGILHVYPYLPVTVKELVLLMLILSDNTATNMLIDLL-GQ +DRIQACINDLGLENTQLNRQMMDAQAAVEG-RDNVITAADLLTCLKVLYREDVLSKDSRD +FLKGSLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLVTHHKR-CYAVVLIDG +LE-HNEYGRRLIADLGRIIS--- +>[subseq from] Beta-lactamase class A n=2 Tax=Pedobacter luteus TaxID=572036 RepID=A0A1T5C2L7_9SPHI +-rKLKVKLEELVKGFQGDVGIYVQNLKTGRIA-EINADTIFPTASMIKVPIMCGVFDKIE +KGKLKYDENLIYKDSLLYAGEDILGSFKDGEIKLGKVQMLSITTSDNTASLWLQKFV-GG +ENINKWLDANGFKSTRMNSRTAGRQGDWRKYGWGQTTPREMATLVKMIHEGKAVSPAASE +RMYRNMIRIYW-DAEALSQIPPYVQAASKQGAVDR-SRSEVVLVNAPHGD-YVFCITTKN +QKTPDNEGYRLIRGLSRLLWNYy +>[subseq from] serine hydrolase n=1 Tax=Salinicola halophilus TaxID=184065 RepID=UPI000DA11552 +------------------------------------------------------------ +-------------------------------------------------------NI-GP +ERVEALRRVLDVEADALEEDMTEAYSRYYDREVNSATLESYAGLLTALVRGELLDDAHRQ +LLYENLKLDTYDAYRLEGGLPREAAFIQKTGTQHR-RACHMGVVEPTDPDRAIVITACTE +AMDEAAPSEALLKRVGEAIAE-- +>[subseq from] serine hydrolase n=1 Tax=Chloracidobacterium thermophilum TaxID=458033 RepID=UPI000738A51C +--AMTRRLQRRLAAFKGKVFCFAKNLDTGETF-GYNPDARVRTASTIKVPIMVEVFAQVA +EGRLRWDDKLTVVRRHEYEGGVLFELTPGTQITVRDAVRLMIVVSDNIATNILLDRI-TT +DAVNDRLAQMGFEHIRSLRKIAGGGEENKKYGIGVATSREMVRLLEGLERGTVVSPEASR +EMLAIMKRQQY-RDGIGRRLR-GVEVANKPGALDH-LRSDIGIVYTKHG-RIAMAITVED +IPCSEAEGHLLIADI-------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium 44-15 TaxID=1895837 RepID=A0A1Q4EZT7_9SPHI +-kKLEREIQNLVSGFHGSVGIYVHDLKRDRIV-AINADTVFPTASIVKIPILLGIMQKIS +TGELDYHQRLTYTNDLFYDGDDILSRFKDSAIELSKVIMLMLTISDNCASLWLQQLAGGG +TRINQVLDSLGYSTTRVNSRTAGREAGRAQYGWGQSSPAEIAALMEKIVKGEIFNREASA +KMLRLLGRQYW-DEQALSAIPAGIFAADKNGAVD-GSRNEVVYVNGPKR-PYIFSIFTKN +NQEKNNEAWVMTRKLSALLWEYf +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rubrivivax sp. TaxID=50259 RepID=A0A519HPY5_9BURK +------AFAALERRVQGRLGFFAIDTGSGRTL-AHRADERFAIASTLKVLLGARVAHGVE +AGRWGWNDAVPLRESERVPHSPAFDRLLPRGATLAELVQGIVVESDNPCANVLLRHCGSP +SGLTDWLREQGDQVTRLDRWETELNENAPGDERDTSTPRAFART---------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium 48-107 TaxID=1895840 RepID=A0A1M3GHI9_9SPHI +-kKLETRLREAVSGFNGDIGIYVKNLKTGKIA-VFNADTIFPTASIVKVPILLGIMQKLE +RGELVYDSTIIYRDSLLYAGEDILGSFKDGEIRLKKVMMLMMTTSDNTASLWLQGLAGGG +TSINQILDSLGFKDTRVNSRTPGREDIRKLYGWGQTTPREMGEIFERIYRNEIFSPAACD +RMMRCMGRNFWDQEEAISVIPPYIEVFSKNGCVDQ-SRNEALLVNAPNN-PYIFCIFTKN +NKRKSNEAWTLTRKISTMLWEYf +>[subseq from] Serine hydrolase n=1 Tax=[Flexibacter] sp. ATCC 35208 TaxID=1936242 RepID=A0A1V2B2P7_9BACT +--KLEKGLRDVISGFHGDVGIYVRNLKTGHYA-EINADSIFPTASIVKVPILVGVFDKIE +KGELQYHQPLIYRDSAKYGGSGIMQYFKDSSTELSVLLALMMSYSDNTASLWNQALAGGG +ERINQLMEQYGLHVTKVNSRTAGRQEIWKIYGWGMTTPREMTTLMIKIRNGEIISKSASE +RMYRLMTHPYY-DEGAISAIPPYVQAAHKSGAVDE-SRSEVVYVNAPHGE-YAFYIGTKN +IATDDNEASILIRKVSKYLWEYf +>[subseq from] Beta-lactamase n=3 Tax=Rhodococcus TaxID=1827 RepID=A0A059MV61_9NOCA +--SAEDRIRDVFADAGCTGWVHARRCDSADEV-TVGGRERVVTASVYKLPLFVAFCRCVD +AGLVDPTAPLTVTPAECTPPTGIAVLHDPVTMSRRDLATSMMTVSDNAAADVLLGEI-GM +GPLDGLLDHLGLTQTKIVGGTADLHRAYDPAYTSATTPEEMTRFLREVWAGRVLSAEQTE +FVRAVMRRQIW-PHRIASAFPRGVSVAGKTGTVGV-IRNEVAVVEFPHEQPVAVAVFTRA +ARVDLPVVDAAIAEAARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium olei TaxID=2571155 RepID=A0A4V5MN51_9SPHI +-kKLEDKLKNEIQNFQGDIGIYVQHVRQNKYV-AIQADTIFPTASIVKVPILVGVFQKIA +EGQLQLNQSFRYDEKRVYGGSGLMQFYKDSATDLSTMISLMLTYSDNVSSLWLQELAGGG +TGINPLLERLGLQQTKINSRTPGRKEIWKKYGWGQTTPKEMATLFLLIRNGQLIGQKYSD +KMYRYLKNQFY-NERSLSQIPPYINTISKTGSVND-ARGEVVLVNAPSGD-YVFCILTKN +NKNDQNEAEVLTRKISNIIWNHf +>[subseq from] serine hydrolase n=1 Tax=Deinococcus maricopensis TaxID=309887 RepID=UPI0011D22E6D +------------RGFPGVAALVVEDLHRGERLvELQGARAFPAASTIKVPLLVHALQRVQ +AGALNLGARVPVPADARVPGAGVLHELDGGLPTVRDLLTLMIVVSDNTATNLVIDLL-GE +AAFNAWLQAEGLRGTHLVRPPHLQNPAQRRGERNRTCADDQVTLLSRLARGELLNPELTA +LALDVLSRQQV-RPILARHLPLSVRVASKSGELR-GVRHDVGVVWLP--RPLVVAVLSEG +GADAR------------------ +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Melainabacteria bacterium RIFCSPLOWO2_12_FULL_35_11 TaxID=1801609 RepID=A0A1F6QD93_9BACT +-------IHAKIKQYGLTCGVCIKPSWFKNPI-NINSDYIFPAASLIKIPIAVILLIKID +KKEISWDRILTLKHYHYAQGAGYLRKKTGTKIKLREAFRLMLTISDNTAANMIIDLLGGV +SSINKQIAVFGLKNTKLVTLLGDFKGA------NKTSPGDLAILLEKSLEGNLLSKSSKR +ILKNTLMDVEN-KSLIKKGLGKYTRFAHKTGTIGI-CVGDAGIIYLPFGKRITISIVVKR +PFNS-LNGQKFIREISRLVYE-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI0005ECD334 +---------------RSNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLVIEAFRQVD +EGLLTLTSVIQRTEKNTVGGAGVLGALPQLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECARNIGLKKTVLNRYMMD-ETAVKQGVDNYTCASDVVECLREIYEGNLLKKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus apodemi TaxID=307126 RepID=UPI00046B0603 +---------SKMANVSGDKTVYVSPVNEDKSY--LLNNQTQSAASVIKLFILAAAYAQQK +IGTIDLSDTYTLKDSDKVGGTGVIQNMDAGQFTYRELLTYMIDESDNTAANIMIEALGGL +DKVNSQIQKMGAKDTKLQRMLMDTAS-LKAGKDNITSAADVGELLKKIYNHKFISKSDSQ +EILAILEKNQD-HDYLVKNIPSEATIYNKTGIMQYGVLNDAAIIKNSKGA-FVAVVMTQN +GEI--SEEQAAMNSLGLALY--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces albireticuli TaxID=1940 RepID=A0A1Z2KUZ9_9ACTN +----RGRVHAAFAEAGVTGWLHAVDIDSGAQL-DAGADQPVVTASVHKLCLLVALHQQAE +AGRLDLSEQTMCPPRDRTPGPTGLAAMLDDVLSLRDAAYLMMAVSDNTAADLILERV-GL +DAVNHTTRCLGLTRTRAVHTFREFLTVLDPAATNRSTPRDMTRLLAAIWRDEACAPEHTA +AMRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA +SSAVLPPADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus apodemi DSM 16634 = JCM 16172 TaxID=1423724 RepID=A0A0R1UBJ8_9LACO +---------SKMANVSGDKTVYVSPVNEDKSY--LLNNQTQSAASVIKLFILAAAYAQQK +IGTIDLSDTYTLKDSDKVGGTGVIQNMDAGQFTYRELLTYMIDESDNTAANIMIEALGGL +DKVNSQIQKMGAKDTKLQRMLMDTAS-LKAGKDNITSAADVGELLKKIYNHKFISKSDSQ +EILAILEKNQD-HDYLVKNIPSEATIYNKTGIMQYGVLNDAAIIKNSKGA-FVAVVMTQN +GEI--SEEQAAMNSLGLALY--- +>[subseq from] serine hydrolase n=1 Tax=Mucilaginibacter sp. L294 TaxID=1643920 RepID=UPI0008376226 +-qKLTSQLKSATKGFNGQVGIYVHNLKTGKTV-GINADTLFPTASMIKVSILSGLMDKIE +KGEMLYNQKLVYRDSLLYAGTDILGSFKDKDIQVSKVALLMITMSDNTASTWLQKLV-GG +DYINNWLDQNGFKVMRVNSRIPARKAIWEVYGWGVTTPREMCRLFTLIHDGKVVSPAASE +RMSRMLNRIFW-DNTALSQIPPYVQTISKQGTVD-ASRSETVLVNAPHGD-YVFSVITKN +NKAPDNEASTLIKKVSALLWHYf +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536R109_9CHLR +----------ALASLPGEAAAFASDTYGHALF-CEREDELFPSASVIKLPLVMTLYADAA +RGRLDLDERVAVG--DRVDGSGVLRHMRDVELSLRDLAMLAVVVSDNTATNRLIERI-GV +DRVGERLREWGCPTSRLSRKMYDFEAA-KRGNENVMTARETVSLLVRLERGECEDRTTSD +AVLAILEQCQD-RTMLLRYLPYGTKVPHKTGTLDE-SRNDAAIV--PGERPVIVAAFTRK +LRD-------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces carpinensis TaxID=66369 RepID=UPI000A364D54 +-----DRIRAAFADAGVTGRLHALDIDSAAQL-GVDADQLVCTASVHKLCLLVALHDRAA +TGDLDLTEPVECSPDGRTPPTGLAAMLDATRLSLRDLAYLMMAVSDNAAADLLLARV-GL +DAVNRTTARLGLETTRAVHTFGAMLAALDPARTNHSTPRDMTRLLRAVWRDEACPPEHGA +AIRRVMALQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +ARATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacteroidetes bacterium HLUCCA01 TaxID=1666909 RepID=A0A0P7XFB1_9BACT +-dDLRTSIQEVIDNINGSIAVAYVNLDHGDTL-YINADRMYHAASTMKTPVMIEAYRQAY +DGGITIMDSVYVHNESIVDGSLYSHDQIGSYVPMRDVIYNMTILSGNLATNLVIDIV-GA +EHVMRTMRELGADNIEVLRGVEDMLA-FQNGMNNRTSARDLAILFEHLARGSAVSPEMDG +DMIAILKDQEF-RSMIPAGLPDNAVVAHKTGSIT-GINHDSGIVYLPDGRSYVLVILTGD +LE-NNEDGIQAGAEISRIIYE-- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3M1PD89_9BACT +---LQARLERLVEGFRGDVGLYVRHLPTGRYA-ALNADTLFPTASLIKVPILITTFDAIE +RGELAYQQELVYRDSLRYPGEDLLGSFKDGEIALSKVVMLMLTMSDNTASLWLQHLCGTG +TAINAWLAAHGFEHTRVNSRTPGREAARARYGWGQTTPREMAELLVMIREGRAVSPAASE +EMYRTLTRTYW-DDEALSQLPPTVQAASKQGAVSR-SRSEVVLVNAPHGD-YVFAVITKN +QEDPDNEGFVLLRDVSRLLWHYf +>[subseq from] serine hydrolase n=1 Tax=Oscillatoriales cyanobacterium MTP1 TaxID=1751289 RepID=UPI001300BECF +--AMTRRLQRRLAAFKGKVFCFAKNLDTGETF-GYNPDARVRTASTIKVPIMVEVFAQVA +EGRLRWDDKLTVVRRHEYEGGVLFELTPGTQITVRDAVRLMIVVSDNIATNILLDRI-TT +DAVNDRLAQMGFEHIRSLRKIAGGGEENKKYGIGVATSREMVRLLEGLERGTVVSPEASR +EMLAIMKRQQY-RDGIGRRLR-GVEVANKPGALDH-LRSDIGIVYTKHG-RIAMAITVED +IPCSEAEGHLLIADI-------- +>[subseq from] Beta-lactamase n=2 Tax=Sphingobacterium deserti TaxID=1229276 RepID=A0A0B8SZE9_9SPHI +-rKLTHNLKDLVAGFEGEIGIYVHHLKSNRTV-EISADSIFPTASIVKVPLLVGVFNKID +SGALKLNANYRYTLEREYGGSGLMQLFKDSAIDLSTMISLMLTYSDNVASIWCQELAGGG +QAINPLMEKLGLNETKVNSRTTGREKLWKQYGWGQTTPREIVKLMTMIRQGEIFSPRLSN +KMYRYLKNQFY-NERSLSQFPAYVATASKTGSVD-AARGEVVFVHGPSGD-FVFAVLTKD +NKDQDNTAEELTRKIANTIWNHf +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7UKG4_9BACT +--SLASRVSERLKRCDAVMGVAAKSLASGEAV-LVDADRRFPTASAIKTAVMVEVFHQIA +EGRFDRDKEVVLTREEKVDGSGVLQDHAGLRLTVGDLLSLMISVSDNTATNLLVGLV-GT +ASVDRRLEGYGLVDTKLFRPTRDGKADHPELERGMSTPRELVRLMELIAEGRVVSRAACD +EMLALLRAQQF-RTMIPRRLPEGIKVGDKPGWDERHVRIDAGVVETPRT-RYVIAICARQ +VRDTDNDALVTGADVARLIHDDf +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora shandongensis TaxID=418495 RepID=A0A1H3LVT4_9PSEU +----------VFGGLPGRIGFAAWDLDEREPV-LVDAERVVHAASTIKVLIMITALRAVR +EGRLGLDAEVELPAE-RAGGFGVLRELPSVTISLRDLITLMIVISDNAATNAVIDAV-GF +EAIRACAADLGCTATQVQRRLMDVNAP----GRNETTALDQARVLAALAGGSALPPELTE +HALDVLSRQQV-RDRLPALLPDGAQCWNKTGELL-GLRHDVGLIG-DDRPRAVVAVLVDE +LTDERSA---------------- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobiales bacterium TaxID=2026801 RepID=A0A2E6L0A9_9BACT +--TLATKLETRIAELDGEVGLYVHHLKKDHSV-LINADELFPAASLIKVPILASLLNKVE +RGELGYQDKLIYTKDRLYPGEDLLGSFANNELTLKKLVFLMITTSDNTASLWCQELAGTG +TTINTWLKQKGFLHTRLNSRTPGRADARDRYGRGQTTPREMAQLLIRIRNRKLVSPAADE +EMARIMGRSYWDGEAI-SSVPPSVSTMSKQGAVN-ASRSEVVLVHAPHGD-YVFCVITKN +QKKHGNEGFSLLRDISRILWEHf +>[subseq from] serine hydrolase n=1 Tax=Saccharopolyspora shandongensis TaxID=418495 RepID=UPI000B8509DF +----------VFGGLPGRIGFAAWDLDEREPV-LVDAERVVHAASTIKVLIMITALRAVR +EGRLGLDAEVELPAE-RAGGFGVLRELPSVTISLRDLITLMIVISDNAATNAVIDAV-GF +EAIRACAADLGCTATQVQRRLMDVNAP----GRNETTALDQARVLAALAGGSALPPELTE +HALDVLSRQQV-RDRLPALLPDGAQCWNKTGELL-GLRHDVGLIG-DDRPRAVVAVLVDE +LTDERSA---------------- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. 1G10 TaxID=2025605 RepID=UPI000B982C78 +--KLSQSWKALAAEHDLKVGGFLLVLDDGRFA-QLNPDIPLPAASSIKTPILLAALDDLD +AGKLRWNEPLPLTKEVMGGGAGWMASRPGTRFPFYEAATEMIRVSDNTATNLLIKRLGGK +AATNAHFQALGLPSTVINNWLPDLEGT------NTTSPRDLARSIALVDIGEKLSPRARD +HFRTIMATSRT-NTLLPAGLLKGLTVLNKTGDIGI-AYADAGLIELPNGKRAVAGFMVKG +PFND-PRSTDLIRAMAAAVSQ-- +>[subseq from] serine hydrolase n=1 Tax=Paenalcaligenes suwonensis TaxID=1202713 RepID=UPI00140D34B3 +--QLESSLTPLLEKEPARISMAVRTLDGVSLF-DWHVQRAMPSASLIKVPMLLCLLEEVA +KGRVSLDDIRALPDSNRAGGTGILSQLPGVQLSLRELAHLMIVLSDNVATNALIDVL-GM +DRINQWCRQAGLAYTELQRHMMDAQAR-AQGKDNWTSAADACTTLLYLLQSPVLPEALRH +EGLQMLADQRE-RGHFAATLPADVELAHKTGSLP-GLRHDAGVMTVGKR-SVVLAVLADG +FT-DARTS--------------- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium drakei TaxID=332101 RepID=A0A2U8DRK9_9CLOT +----EELLKNSLKNSESKYSLAVKNLKSKEIC-YMNVHEVVPSASIIKLFIMAEAFNENK +MRKLDLHDIIKINNDKKVPFSIVSLLNSVEQYSIKDLITLMIIQSDNTAANVLIDFL-GI +DNINNFIKETGFKNTILGRKMMDFEGD-KGGKDNYTSAYDVFLFLEKLYNHNLVGEKEDK +FMIDILSHQLD-FSMMRIDMLDDLKIAHKTGDLNC-LKHDAGIVYSEKVGDYIFVMFTYE +AQ-SDGYARKLICKTSKQIYNYf +>[subseq from] Serine hydrolase n=1 Tax=Niabella ginsenosidivorans TaxID=1176587 RepID=A0A1A9I322_9BACT +-kKLKVLIENAISGFHGDIGVYVHHLKKNTSV-AVNADTIFPTASIVKVPILTGVFNKIA +QKELKLSQEFVYDAKRAYGGSGLMQFYKDSATDLSTMISLMLSYSDNVAAIWLQELAGGG +AAINPLMDQLGLRNTKVNSRTEGRQDLWKKYGWGQTTPREMAQLFTLIRQGKVIDARYSD +KMYRYLKNQFY-NGRSLSQIPATVNTICKTGSIDD-ARGEVVLVNAPGGD-YVFCILTKN +NKTDDNEAEVLTRKLSNIIWNHf +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium BR5-29 TaxID=2607284 RepID=A0A5J5IF05_9BACT +-kKLENKLHALIDSFHGTAGIYVRNLKTGKEV-AINADTIFPTASIVKLPILIGIFNKIE +EGEFTYHQPMLYRDSMAHGGSGLMQYFKDSSTDLSNVITLMITHSDNTAAIWCEKLAGGG +LTINEWLTEHGFQSTRLNSRTPGRKNNYDEYGWGQTTPREMADLLVMIRQGKAVTPAASE +RMYRILTHVYW-DDYALSKIPPYVQVASKQGMVD-ASRSEAVLVNAPHGD-YVFYIATKN +NVEPGNEAWQLARKVSALIWNYf +>[subseq from] serine hydrolase n=1 Tax=Deinococcus reticulitermitis TaxID=856736 RepID=UPI000B860DA3 +-----------ARGYAGTAGLVVLDLQTGETLyEEHADRPFPAASTIKVPLLVLALQAAE +RGELVLTGRVTLQAEDRVPGAGVLHELEPGLLSWRDVLTLMIVVSDNTATNLLIEQL-GL +EACNAGFRALGLRATRLVGPLERRNAAQRRGERNRTSAREQAGLLRQLGRGDLLGPEHTG +WAQDVLFRQQV-RPLIGRGVPADYRLASKSGELR-GVQHDVALLHTP--RPLAVALLSEG +GTDPREHP--------------- +>[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora alkaliphila TaxID=1783498 RepID=UPI0013B69F65 +---LGEQLAGLAAESPGTWAFAVRE--QGRAVaSVRGDVVVPAASTIKVALMVLALQDVE +AERCRLDSVLRVP-DERVGGSGVLRLLPSVRLRLDETLELMIGISDNTAANMVIGML-GV +DDVARRVAALGARNTRLERRLMDLEAA-RQGRDNVTTADDQALLLDLLAGETVLSVELRQ +HALEILGRQQV-NDRMPAALGPDVVCRHKTGELE-GVRHDVGLLEFDGRQ-VAFAALGTD +LPEQAAPAGSVIAGAARMVVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Halopolyspora algeriensis TaxID=1500506 RepID=A0A368VDY0_9ACTN +------------DGFPGRVSVAAWALDESDTV-TVQAHRPVQAASTIKVLVLITALRHVR +DGRLALDTELPLPAEHRVGGTGVLRELASVSLALADLLALMIVVSDNTATGVVIDAV-GF +DAINACARDLGCTTTRVQRHLMDIDAMIDG-WDNVTSALDQARVLDRLARGTALPDELTH +WALDVLSRQQM-RDRLPALLPVGAECWNKTGEQI-GLRHDVGLIGRAGKPQAVIAVLVDQ +LTD-------------------- +>[subseq from] Beta-lactamase n=2 Tax=Lactobacillus TaxID=1578 RepID=A0A0R1WQ18_9LACO +-------------NISGKSSIYVTTAKSNQSY-SVNN-RPQLSASVIKLFILGAAFMEAN +DNHLNLNDSYILKDSDKVGGTGILQNKPNGTYTYRQLLTYMIDFSDNTATNIIIDKLGGV +ERTNFLISKFNVKNTKLQRKMMNFNAK----KDNYTSAEDTALFLKQLYNHQLLSKSSDE +EMLKILKQNTD-HSKLLKNLPASTVTYNKTGINDQGIQNDAAIISNKNGA-IIVVVLSEK +GNSS--QQ--------------- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A359KR52_9CHLR +--ALQSTIDSLMAGVSGVTAVEIENPDGSMLA-AWNAGEQIEAASLYKLGIMVETYRQRD +AGMLTFDDQIVLQDYHFSEGSDVFSEEVGMTTDVGTLLQAMITVSSNVAATALLEYV-GT +DNVNATMASLGLSSTVI-RWYPGPSGVRANAAMNVTSAADMASLFRMLLAGEVVDAEASR +EMLDLLARQEI-NDRLPAYLPDGTVVAHKTGNLD-GLMHDAGIIYAPTG-PVIVVVMTED +VD--DAASTDLIAQIGLLAYET- +>[subseq from] Beta-lactamase class A n=1 Tax=[Clostridium] celerecrescens 18A TaxID=1286362 RepID=A0A2M8ZC42_9FIRM +-------IIKKLERVPGKISFFYEDLKTGKVF-AYHEQEPMMAASIIKLFVMAAAFEKSK +KGTFQMDELFAVKREDWVPCGALTYLHDGILVTGLDLITLMIIFSDNTATNILIDIL-GI +EEINEMIRELGFRHTLLQRKMYDVERS-SRGIQNYITADETGRLLKMMYEGTLIDRQSSE +AMISILKNQQL-CSKIPFYLQESPEIAHKTGEDT-GITHDVGIVYGK--EPFL-VCFCGN +ET-DTPAFERVMAEVSLELYN-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A3M2D4S7_9BACT +-eSLDERIKKEIAGFQGSVYIYAKNIDNGKTY-ELRADERVRTASTIKLPIMVEVFAQVA +EGKLKWDEKFVLKN--KISGSGILGEFTEGTLDLKTLVNLMIVVSDNTATNMILDRI-TT +DAVNERMEKLGFQHIRSLRKIGGGGEAKIIDEGGVATMREMGRLLEMIERKEIISKEACK +EMIEILRRQQY-TDGLGRGLLETTPIASKSGTLDR-LRSDVGIIYTRKGR-IVMAITVDD +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Deinococcus marmoris TaxID=249408 RepID=A0A1U7P1H9_9DEIO +------------QGYVGEIGLRVCDLTGRELF-ALNPERVFPAASTIKVPLLILALAWAQ +AGRLDLESRVTLEATDRVSGAGVLHELGPGLLSWRDVLTLMIIVSDNTATNLVIGRL-GV +EAVNDWLTAHGWTETRLVGKLQQRNAAQLRGERNRTTAADQTDLLGRLVRGELLDAAHTA +LALDILERQQF-RDLIGRGLPRAYRLASKSGELD-GVHHDVGVLYTP--RPLVIALLTGG +GT--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Salegentibacter sp. T436 TaxID=1729720 RepID=A0A1L6R3E9_9FLAO +---LEQKLEELTASFKGDVGVYVKHLKTGKEA-AINADSIFPTASIVKVPILVKIFDKIE +EGELSYRDSLVYSEDRIYGGSGLMQFYKDSTTDLRTLVALMISYSDNVTSLWNQELAGGG +EAINKLMTELGLEHTRVNSRTEGRDKDWEKYGWGQTTPREMASILEQIRKRELVSAAASD +EMYRLLGNSFY-QDYALSQVPPYIQVAAKQGMVNK-SRSELFMVNGPSGD-YVCYIATKN +NEDEDNEAWQLQREISNLLWNYf +>[subseq from] ClassA (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SLL1_9BACT +------------------------------------------------------------ +-------------------YSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT +SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK +FLEDTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD +SMEDDKTNAAIIAQISKAVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. H33E-04 TaxID=2703787 RepID=A0A6B9ZCG6_9BACT +-rKLEKGLRDIIAGFQGDVGIYVRNLKTGRYV-DINADTIFPTASIVKVPILVGVFDKIE +KGELTYHQPLIYRDSIKYGGSGLMQFFKDSTTELSVLLALMMSYSDNTTSLWNQALAGGG +QRINELMAQYGLTVTRVNSRTPGREAFRTTYGWGMTTPREMAELVVKIRNGAVISKDASA +RMYRLMSHGYY-DETGLSQIPPYVQAVHKTGSVD-ASRSEVILVNAPHGE-YVFYVGTKN +NKTDDNEAEKLIIKISGYLWKYy +>[subseq from] Serine hydrolase n=1 Tax=Antarcticibacterium flavum TaxID=2058175 RepID=A0A5B7X4H3_9FLAO +--NLEGQLEQLLSNFNGTAGVYVYNIATGKEA-AINADTIFPTASVIKVPILVTLFNKIQ +EGQLHLNDSLVYTEDRIYGGSGLMQFYKDSTTDLRTLAALMITYSDNVTSLWSQELAGGG +EEINRFMESLGLEDTRVNSRTKGREEIWKKYGWGQTTPREMVSILVKIRNRELINEAASD +EMYRMLTNSFY-TEYALSQIPPYVQTAAKQGMVNR-SRSELVMVNAPGGD-YVFYIATKD +NED-------------------- +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / NCIB 11800 / UQM 2034) TaxID=485918 RepID=C7PH33_CHIPD +-rKLEKGLRAIITGFQGDVGIYVRNLKTGRYV-DINADTIFPTASIVKVPILVGVFDKIE +KGELSYHQPLMYRDSIKYGGSGLMQFFKDSTTDLSVLVALMMAYSDNTTSLWNQALAGGG +QRINELMAQYGLNNTRVNSRTPGREAIRNVYGWGMTTPREMSELLVKIRKGEVISENASS +RMYRLMTHGYY-DEVGLSQIPPYTQAAHKSGSVD-ASRSEVILVNAPHGE-YVFYVGTKN +NKTNENEAENLIRKVSAYLWDYy +>[subseq from] Serine hydrolase n=1 Tax=Clostridia bacterium TaxID=2044939 RepID=A0A2V2FD76_9FIRM +------------SRVPGDVGFYFKDLTTGEEL-GRNENEMFQAASVIKLPMFAVVAKFVA +EGKASWEDRLVAHNEERVPPCGALWFFEDEPVRLKTLCGLMITISDNMATNMIMRHF-GI +ETFNREFREIGLEKTHIERLLFDSAAG-AQGKQNKIVPREMGCLLERVYRHSFVNETVSK +CIEDTLLEQQI-NHKIPGYLRGEVDVAHKTGEDD-GITNDVGIVYA--REPFVICFATNN +TD--VPEAERAMREISLALAD-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces parvulus TaxID=146923 RepID=A0A191V0L9_9ACTN +-----ARLDAAFAEAGVTGWLHAVDVDSGAQV-EAGADQAVCTASVHKVCVLVTLHERAA +AGALDLTEQVECPPAGRTPGPTGLSAMLDPVMSLRDAAFWMMSVSDNTAADLLLRRV-GL +DAVNRTAERLGLTRTRAVYGFGEMLAALDPARTNRSTPRDMTRLLAAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium CG12_big_fil_rev_8_21_14_0_65_60_17 TaxID=1973924 RepID=A0A2H0JNL2_9BACT +---LEEQLSERLESLDGTSGLYLRHLPTGREI-SIRADSVYPTASMIKVTILAALVDRVE +RGELAWTEKLVYRDSLFYSDADITGELQDGAVSLDMLARLMTSYSDNTASLWLQELAGTG +VAINAWLASEGFETTRMNSRTPGRRSDWEAYGWGQTSPREMAQLMVMIAEGRAVSPAASD +RMLRLLSGSYW-DGEMLSVLPPGVEVASKQGAVS-ASKSEVVFVHAPGGA-YVLCVITNK +QTAQDNEGYVLLRDVSRLVWE-- +>[subseq from] Beta-lactamase class A n=2 Tax=Bacillus TaxID=1386 RepID=A0A366JKJ7_BACFI +-hTLKAEILDLASCCEGHVAVYIH---TGDGViETNADDVISSASLIKVPILLAGLSQAE +NNLLQLDEEAEVNDTVRVGGAGVLQAMSKDLVKVIDLMTLMVIVSDNTATNLIIERL-GI +EKINQLIKGLGFNCTELNRKMMDFE-ALKNGMDNITTARDMVYGMKALAEHSLLSGKYTE +KALDILEKQQYKNKLANTIDTEKVKVASKTGELP-GIEHDCAIFTYKGN-TVYAAVLVDQ +LQ-SQAAGGEVLAAIGSRI---- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7Z511_9BACT +--DLESRIREEVAHFHGTMGVVARNLDTGERI-SVNGDMRFPTASLIKVAVMVEVFHGFA +DGSLRRDQTVTLSDADRAGTVPLNVLHAGAVLTVSDLLRLMIAWSDNTATNLLVRLA-GI +VRTNRRMEAYGLANTKIFRPTRDGKAVFPELERGMTTPAEAARLFESIAEGKAVDRAASD +EMLAILALQQD-RAMIPRRLPDRIFVASKTGWDEEKVRNDAAYVKGPRG-RYVLAILVRR +GKDKDSEALVTGARISRMVYDAf +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E4I1Y8_9BACT +--SLEETVEKQLQSLDAETSFYAKHLPSGKEI-SIRADQPMNPLSVIKIPMMILAFQDTE +NGQFDLDQRYHIRAEDMRGGSGLLQTFTTGLPTYRDLITQMIITSDNTATDIILNKL-TM +ERVNLFLEENGYLETIVKSSTGDLFRRFEGDSTGRTTAREMGMLLEQIENAELTSRKSAD +EMTNILKRQFY-SSRIPRFLRGKATVGHKTGDWPPHAGNDVAILYYDGG-PSIMAIFTNQ +NKGDFVELESTIGRIAEELVSRw +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E7D630_9PLAN +-----DELDAVAKKFDGRIGFFVRGLASGADY-GWNSDERFPPASVIKLPVMIELYRQAA +DGRLDLDKKLRLPDDISTHGTGVLKKKKRPVLPLREYADLMMIHSDNMATDFIIRTV-SP +TATNRFLDVQGFRNTRVALELGRWHYYSDSLKNNVCAPREIVLLLERLYNGELTSEKNKQ +AILEPMRASTH-KNTIARHVKRGIQVANKYGGSQR-IAADAGIIEIPDR-PIAIACFALA +NDPTDRSGRDILAEMCRLAIK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Anaerocolumna aminovalerica TaxID=1527 RepID=A0A1I5GLG6_9FIRM +-------------KDGAEISLLVKDFKTQDILySHEDTKEVVSASIIKVPIMLTALEQVQ +KGKLELDSLIELKDAGILEDTEVFE-YGGGKYTLEELLVWMIIESDNTATNCLIDLL-SM +ETINTFCKKHSLKSTKLERRMLDFQAV-QEGRNNYTSAGDMAILYEELYNRTILTPDLCN +TALGILKRQRH-KQLSLRYIYDDITVAHKTGSLDN-LDHDAGIFYLPNIQ-YYFGAFVWN +AP-SNEYASKWIGRISKGIYEYy +>[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00132FAB33 +------------------------------------------------------------ +------------------------------------------------------------ +---------MGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ +QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPAGKPSRIVVIYTTG +SQATMDERNRQIAEIGASLIKHw +>[subseq from] Class A beta-lactamase n=1 Tax=Brevibacillus formosus TaxID=54913 RepID=A0A220MJX4_9BACL +--ELENRLSAIIGQAEGTWGVVVEELGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE +QGHFRLDDQLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK +TQIDQTMIDLGMRQSYYSRKLMIYPLD--ITENNMITAGDVASMLGHLATGSYLSRRACK +EMIAIMKKQQV-RNGLPSQLPPGWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKN +VT--AQSALNTLGLLGRAVYDY- +>[subseq from] Beta-lactamase class A (Fragment) n=1 Tax=Microgenomates group bacterium LiPW_16 TaxID=2017212 RepID=A0A554IBL7_9BACT +--NLLNEIKKIIDKSPGSWSIYVYDLTTNQGF-GINETAIFTAASVNKVPILAVLYHLTD +KGEIDLDQQVTLQASDIQNTGSIRYDPPGTTYSLKTLARLMMEKSDNTAAHLLGRQIIGF +DKIQELLDAWGLTQTNMEE--------------NKTSLGDLLKLFLKIYRGELAGQALTA +EMIGFMDDSDF-EDRIPALLPKGTKVYHKIGDEV-GNIHDVGIVELDKGT-YFIGVLTSD +IV-DELAAKKTIAQISKLVFKY- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2G4FV38_9BACT +----QRLLDAELARIPGTAGVWVKHLTTGEEA-AVNADRVFNSASVIKIPVMLLAFQLAD +QGKLSLTERITIQAADVRGGSGVFRYHDAGLPTLRDVLLQMIITSDNTATDLAIGKVGGI +GPVNAMIKRAGYDPLQLTMTTGELFANDPAFWLGSMTPRATGRMLEDIQRCSVASKAACA +DMLQMFRAQQSGARRLPHFLA--VPVGHKTGDFPPVLANDVGIIYARSG-PIVVAFFLNG +IRGSYAEAEDHIGRVAQLIVEYf +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A4V2APD1_9BACT +-kKLERQVQELIKGFNGDIGVYIKNLENGRTV-AINADTVFPTASMVKIPILIGVMDKIN +RGELTYHQSLTYKDSLLYAGVDILGSFKNDEIDMSKVMMLMLTTSDNTASLWLQSLAGKG +TRINELLDSMGFVATRVNSRTPGREAIRSIYGWGQTSPREMATLMEKIANGEIISKERSA +QMLRLLGRNYWDDNAI-SQIPSDVFVASKNGAVNE-SRSEVLFVNGR-GARYVFCICTKN +IKQPGNEAWVLTRNLSKLLWEHf +>[subseq from] Beta-lactamase n=1 Tax=Rufibacter sp. DG15C TaxID=1379909 RepID=A0A127B1R9_9BACT +-kKLTQKLEALTKGFQGEVGIYVKHLKTGKTV-AINADTLFPTASMIKVPIMVGVFNKIE +RGELDPKAILQYRDSLLYAGEDIVGNFKDSSVALSKVQMLSITTSDNTGSLWLQHLAGTG +TAINQWLESNGFQDTRMNSRTPGRRPNWEKYGWGQTTPREMATLLTMIREGRAVSPAASE +RMYRNLGRIYY-DAEALSQIPPYVHTASKSGAVNQ-SRSEVVLVNAPHGD-YVFCIITKN +QKERSNAGFTLIREVSKVLWQHf +>[subseq from] Uncharacterized protein n=1 Tax=Halobacillus karajensis TaxID=195088 RepID=A0A024P480_9BACI +-----VSIAKLAANVDAEVSIFIRY--GDHSV-RINEDCVLPAASTIKIPILMEAFRQRD +EEMIDFSERISISPKDRVGGDGVLSLLIESAMEFEDLLTLMIVVSDNTASNILMDEL-GI +SAINDLCQSLGCPSTKIRRLFMDFDA-MQAGINNTTTASDMMRLITALDQGKIGGKSGAT +QMIEILQHQRY-TSGLPAYMTSNIKFATKTGQLP-GICHDLGIFKYREQK-VYAVVMFHQ +LA-EGEAGRRALGDIGKVI---- +>[subseq from] serine hydrolase n=1 Tax=Halobacillus karajensis TaxID=195088 RepID=UPI0008A786DC +-----VSIAKLAANVDAEVSIFIRY--GDHSV-RINEDCVLPAASTIKIPILMEAFRQRD +EEMIDFSERISISPKDRVGGDGVLSLLTESAMEFEDLLTLMIVVSDNTASNILMDEL-GI +SAINDLCQSLGCPSTKIRRLFMDFDA-MQAGINNTTTASDMMRLITALDQGKIGGKSGAT +QMIEILQHQRY-TSGLPAYMTSNIKFATKTGQLP-GICHDLGIFKYREQK-VYAVVMFHQ +LA-EGEAGRRALGDIGKVI---- +>[subseq from] Serine hydrolase n=2 Tax=Synechococcales TaxID=1890424 RepID=A0A358C000_9CYAN +---LSKRFSQLAAAQNLKAGAFVLVLDTGSYA-QLNADTPLPAASAIKTPILLAAFEAID +QGKAKLNEKLTISKVVVGGGSGWMGSQPLGSFSFNEVATEMIRVSDNTATNLLIQRLGGK +TALNAKFLQLGLTGTAIKNWLPDLDGT------NTSTPRDQARTIALVETGKELSPRSRD +LFRSTLGSSRT-DTLIPTGWLQGVRVFNKTGDIGI-AYVDSGLIELADGRRAVASYMVKG +PFND-PRSTDLIRAMAAAT---- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus pyridinivorans KG-16 TaxID=1441730 RepID=A0A0V9UKM9_9NOCA +----------------------------AATL-SVRGDERVVLASVYKLPLFLAFCAEVD +AGRLDASGQQRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT +TAVEELLARLGLTRTRIIGGTADVYQAYDPAYTSATTPAEMTRLLEAVWSGSVLSPESTA +FAQQVMRAQIW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus onubensis TaxID=1571209 RepID=UPI000C0C08C3 +--NLRLSIDSLLEDFSGSISLEVRSRQGDKII-SYNENEVFPTASTIKVFILGAMLEQVQ +NDQYSLTDLIEMRAGDQVGGSGVIKEFTPGSYPIRDVATAMIILSDNTATNMILELVGGI +DVVNTHIKKYGYTYTELRNIIDF-Q-AIGEDVENVSTSAEFVDYLEKILNNKILKPEIKD +VMIDIMARQQY-LDLFPRYIPQDIQIANKTGFFM-GVRCDVGYIFIKNKQ-YVFTVFSKN +CANPENEAAVLIGKLGKEI---- +>[subseq from] Uncharacterized protein n=1 Tax=Handelsmanbacteria sp. (strain RIFCSPLOWO2_12_FULL_64_10) TaxID=1817868 RepID=A0A1F6C8H9_HANXR +-dELLRKIVEVGRERRGTVGVAARRLDSGEEV-RYEAEGEYPTASVIKLPILVALYRKAA +EGKLDLDERMTPKPEHYMTGTGVLNDLSRDILSLRDLARLMIIVSDNVATNLIIDLV-GR +AYINEAMQEYGLKDTAVRQRLDYISKAWPDFRRAISSPSDLVLLLSKLSRREILTPEACD +EVIDTLIRNQY-QEMLPRHLPRVLWVADKPGMLWD-VRADAGLVATPGL-TYAVAIMLYG +IKGEDTDGAHIVARLSRLIYDYf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces eurocidicus TaxID=66423 RepID=A0A2N8NUE4_STREU +----RGRVRAAFAEAGVTGWLHAVDIDSGAQL-DAGADQPVVTASVHKLCLLVALHQQAE +AGRLDLSEQTTCPPRDRTPGPTGLAAMLDDVLSLRDAAYLMMAVSDNTAADLILERV-GL +DAVNRTTWRLGLTGTHAVHTFREFLTVLDPAATNHSTPRDMTRLLAAIWRDEACAPEHTA +AMRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA +SSAVLPPADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces leeuwenhoekii TaxID=1437453 RepID=A0A0F7VLS6_9ACTN +--SIARRIGAAFAEAGVTGHLHAVDIDSGAEV-DAGADQPVVTASVHKLCLLVALHEQAE +AGRLDLAERVECPADDRTSGPTGLAAMLDPVISLRDLAYLMMAVSDNGAADLLLRRV-GL +DAVNATTARLGLERTCALHTFRELFAALDPARTNHTTPRDMTRLLGAVWRDEACLPGHCA +AMRRILGLQVW-PHRLASGFPDDVRVSGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRS +ASATLPAADAVIGTAARMAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus wulumuqiensis TaxID=980427 RepID=A0A345IJR4_9DEIO +-------------GYAGEVGLLVTDFGGRELY-ACAADAPFASASTIKLPLLLMALEQAG +RGDLDLAERVTLRAEDRVPGAGVLHELSPGLLTWQDVLTLMIVVSDNTATNLLIERL-GQ +DDFNAWLTARGLTRTRLVGPLERQNAAQRRGERNRTSARDQVALLLSLLRGDGLTPQMQQ +LGLDILGRQHL-RDLIGRGVPAGYRVASKSGELR-GVHHDVGLLWTP--RPLVVALLSQG +GED--PREHPANRDVTRLAA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Asanoa ferruginea TaxID=53367 RepID=A0A3D9ZTG3_9ACTN +---LTARLQAIVASAPVTAGVSVRDLSGDQQI-SVAGRFRPKAASLIKLWVLVELMRRID +CGQAAYTDGVLVLPEDVVGGTGELQHETFPQVTLFRLAQYMIKYSDNTATNVLIDYLGGF +EPVNALIDSMNQRETVLGRKMLATP-----PPENFTSPDDVISLLGAVWDRQVLRQVNRD +LMLSFMLEQTL-NGKIPAALPSGVPVAHKTGELPD-VSHDVGYYLIPGT-EIAVAFLTAG +VE---TEGAETVRQLARAVYDY- +>[subseq from] serine hydrolase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=UPI0009E34FDA +---LREEMMGVVQECSGKVSFSVLF--DDESL-SWEEDRRISSASLIKLPILMAAYEQIQ +TGRLQADAMIVLRHEDHEEGAGVLNGHDGLTLSIEDLLTLMITVSDNTATNRLIELI-GM +DFINRFCLDWNLKGTFLNRKMMDFPS-LEMGKDNWTSSEDVVSCLTLINEGPF-EEASRK +KMLTMLSRQQF-RDKLPALLGDDVKVFNKTGELP-GVEHDCAIIESASGKYAYVAVLTDE +LPAP-EEGRRVIRTVGKLIGD-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus hilgardii TaxID=1588 RepID=UPI00019C520A +--------SQCVAASSGKTSIYVSELDSKNSV--VENNRVQRSASVIKIFIMIEAFRQIK +AGQLTLNQQVIIPADDRVGGTGELANQNTHQLSVKQLLRLMIRNSDNTATNVLIDKLGGL +AVINAEINRLGCSHTKLRRKMLDYR-ALQNGKDNVTSVSDLGKTLMALSGHRLLGHPYDS +EMLQLLRYNSN-QSKLSALISRKAVIYNKTGEFDYGVQNDAAIVKKGKRA-FVVVVLSEN +GTQQ--KQINAMQMLGKR----- +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura geliboluensis TaxID=882440 RepID=A0A5S4GSC9_9ACTN +-----RRIEEEFRSAGVTGVLHVVDIDTGREV-AIGAAEPVVLASVFKVPLLVAFHRLAA +AGALDPAEQVTLRPQDRTAPTGVSALLDEVRMSLRDLTCLMITVSDNAAADTVLDRVGGR +DAVNAAAAALGLRDTVVEVTGRELHEALDPARTSRSTPRDMTRLLSMIWRDEAAPAADCA +AMRRLLGLQVW-PHRLSSGFPDDVVVSGKTGTLLT-VRNEVGAVEYPDGARYAVAIFTRS +PTAVLPRADAVIGTTARLAIE-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. CL-2 TaxID=1499684 RepID=UPI0009DC99CF +------RVAQKLSAYNFNYSILFKNLTSLETI-TWCEKATFPSASTIKIFIAIEAFNQIN +KELIFEDDIILLDDTMKVGGSGILSSYSNNSISIKKLIYLMMAESDNTATNILIDIL-DI +NNINTTINKLLCKNSALNRKMMDFDS-IKKGIDNYTSALDLAIVLERLYTNSCINKKYDT +LILNIMKDCTN-NSKIPSKLPSHIKISHKTGELDY-IENDAGIIFTPYGD-YILIILTEG +YNNS--VEIEAISEISKIIYDSy +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus modestisalitolerans TaxID=1457219 RepID=UPI0010F67A32 +--QVRADINNTIAPLSGDSEVYVTPVKGSQQV-SVNNGSQ-RSASTIKIFILVTAYALEK +EGAFDLNDEYTISDDDKVGGTGVMRTMADGTLTYHEVLTHMIADSDNMAANVMIDALGGF +KLINNKIESLGATDTQLNRKMMDTD-ALEDGDDNVTSAEDLGQTLKKMYNHKLVSADADR +AMLTILAQNHN-RTKLPHDLPGDATVYNKTGEFDYGVQNDAAIMANKRGA-FVVVVLSQD +GQQTEQ--V-------------- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000FF8E520 +--QIKDDISSTVGSINGTNSVYVSPVDSKQTV-LVNNG-SQRSASSIKIFIMVTAYAMAK +EGVFNLDDTHTVSDSEKVGGTGVIQNMDAGTLSYQEIIAHMIDDSDNTAANIMIEKLGGF +QLINTKIKNMGATDTKLRRKMMDTK-ALDAGRDNTTSARDMGATLKKIYNHQLVSQQADD +AMLTILSKNQN-HNKLPKQVPSSATIYNKTGEYDYGVQNDAEIVKNSRGA-FVAVVLSED +GEETD--QVDAM----------- +>[subseq from] serine hydrolase n=1 Tax=Pseudoflavitalea sp. X16 TaxID=2716334 RepID=UPI00141E9F1F +-rKLQEKITALIQAQRGVVGVYVKNLRTGKVA-EFQADSLFPTASMVKVPILVGVMDKIE +KGELPYNQPLEYKDSLLYAGEDILGSFKSGEIELSKVMMLMLTMSDNTASLWLQSLAGTG +ARINELLDSLGLQFTRVNSRTPGREENRKQYGWGQTTPREMTTLMEKIYRGEVISKKASE +RMLRVLGRNYHDVNGI-SQVPPYVFVASKTGEVNQ-SRNETLLVMAPHG-PYVYTISTKK +LENPSNEGWVLCRKLSALLWHY- +>[subseq from] Serine hydrolase n=1 Tax=Cytophagaceae bacterium BCCC1 TaxID=2015573 RepID=A0A257IZ60_9BACT +--RLKDQIIELMSKTEGDFGLAFKNLENSDTI-FINAHEYFHAASTMKTPVMLEIFKQEK +QGKFKISDSIIVQNESIVDKSRYSYRKIGQKMTIHDLTYEMMTKSSNLATNILIDKV-GA +KNVMKLLSSLNIKENIVLRGVEDQK-AFEAGLNNKTTPFGLMQIFEHI----ALTQSRNS +LMMEILFEQKF-NEIIPAQLPKTVKVAHKTGSIT-GVQHDSGIVFLPDGRKYVLILLSKN +LK-NADDGVKTLAVISKLIYDH- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. HV4-5-A1G TaxID=2004595 RepID=A0A5M9NRY4_9CLOT +----------KVGKLKGKVGFCYKDLDSGDSF-GVNEDEPFIAASIIKIPILIEAYRQFR +EKILFKEELVEIKESDRVPSCGAAAYHPGARLMLKDLCVLMIVLSDNMAANILIKKL-KM +SNINNTMKQLGMKKTKVNRILFDSDA-EKAGKQNYFAPDEILKLFEMMWKGSLISRQDSE +DMIKIFKLQQI-NYKMPYLLSEDICVAHKTGDDE-GITHDAGIVYA--RKPFILCFASNE +TD--VNETDEFIRKTTREIFE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4Y5R2G0_ECOLX +------------------------------------------------------------ +--------------------APIMKAYQGDQVPVQQLLQYSVSHSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA +LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD +SAES------------------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces shenzhenensis TaxID=943815 RepID=A0A3M0I8B8_9ACTN +---VPARIHAAFAEAGVTGRLHALDIDSGAQL-DVGADQPVCTASVHKLCLLVALHEQAA +AGRLDLGEQVECPPAGRTAGSTGLAAMLDSALSLRDIAYLMMAVSDNAAADLLLHRV-GL +DAVNRTTARLGLTRTHAVHTFGDLLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA +AVRRLLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT +PNATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2E4RKW1_9BACT +-dSLEERIVGLLDSEKGEFAVAYKNLSTGETI-LINENEEFHAASTMKTPVMIEAFKXXX +EGLISLDDSILIKNESIVDGSIFKYEKIGSYLTLKELIYDMITISSNFATNLVIDYI-GT +KEXNNTMRXLGANNINVLRGVEDIKA-FNNGMNXTTTAXDLLKIYENLAEGNVISSDISD +EMINILKNQKY-DDIXPKYLPKSVEVAXKDGWIS-GVRHDSGIIFLEXNKKYVLVXLSKK +LENE-IXGADXLAKISLEIY--- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium alkalisoli TaxID=1874115 RepID=A0A4U0H1U2_9SPHI +-kKLEDKLNNEIQHFKGEIGIYIQHIRSNRYV-AIHADTIFPTASIVKIPILVGVFQKIA +DGQLQVNQAFRYDKNRVYGGSGLMQFYKDSATDLSTMISLMLSYSDNVASLWLQELAGGG +TVINPLLEKLGLQHTKINSRTPGREDIWKKYGWGQTTPREMATLFLSIRNGQVIDKRHSD +KMYRYLKNQFY-NGRSLSQIPSHINTISKTGSVND-ARGEVVLVNAPSGD-YVFCILTKN +NENDQNEAEVLTRKISNIIWNHf +>[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Heliorestis convoluta TaxID=356322 RepID=A0A5Q2MZT4_9FIRM +-sQLEQKIKSYLYRFSGTYGLYVEDLATGATL-EINADKSFPAASVIKVPLILFLYSLAI +DDRIDLDEEMVLEAGDIESGTGILKTAVGTTYTLRQLAQYTIEYSDNSATNMLMRRL-GR +ENFYFFLRLMGAEIIPLGPG-----------KGNIMCARDAALYLKGVMALRELHPEYGQ +EVLQYLLNSKF-DDRIPAGIPKGIQVANKIGTQVN-VVNDAAIVLLN-GKPYVIAILCSH +IHE--QEAVGAIAQISKLVFEY- +>[subseq from] Serine hydrolase n=1 Tax=Cytophagia bacterium TaxID=2026730 RepID=A0A2E5GTU4_9BACT +---LEEEIIYKFENFEGDFALAYKDLSSGNQI-LYNEKQIFHAAXTMKTPLMIEVFNQVN +KNXFNLSDSIFIINQSIVDDSFFSYESLGKKKSIYSLVFDMITVSSNFATNLIIDYV-GA +ENVNKTMRKIGAMDINVLRGVEDIKA-FEKGLNNTTNAYDLMIIYEKLAKGEIINKSSSE +KMIEILLNQKY-KDKIGLYLPKNVKVATKDGIISS-AVHDSGIIFLPDGRKYILVILSKN +LN-DIENASKLIAEISKIIYEY- +>[subseq from] Serine hydrolase n=1 Tax=Caulobacter zeae TaxID=2055137 RepID=A0A2N5DD20_9CAUL +heTMSHKLTAIAERAPGDLGVAVQDLTTPQRA-TVAGDHLFPLAGIWTAALGAAVLAEVE +AKALSLRETITIEDVDLSPPSGVADAWPSRRWTVEELLKHAVAGGDNTAADVLMKRIGGP +GAVTAWLDLKKVENLRVDRYARQLLPDYLADPHDSTTPLAAVRFLEALNQAELTSQEGRR +RMLRMMEAAA--GERLRPALPAGARLAAITSATPTAADNVLAMVRLKDGRRFALAILLKA +SPLEEADRDALMLEVTRTVLQ-- +>[subseq from] Putative beta-lactamase n=1 Tax=Lactobacillus pentosus IG1 TaxID=1042160 RepID=G0M5K5_LACPE +--QIRNDISSTVGAISGTNSVYVSPVNSKQTV--LVNDGSQRSASSIKIFIMVTAYAMAK +EGVFNLTDTHTVTDSEKVGGTGVIQNMDAGTLSYQEIIEHMIDDSDNTAANIMIEKLGGF +DLINNKISNMGATDTKLRRKMMDTK-ALDDGKDNTTSAHDMGMTLKKIYNHQLVSRQADE +EMLTILAKNQN-RTKLPKDLPSSATVYNKTGEYDYGVQNDAEIVKNSHGA-FVAVVLSED +GDQ--NDQIDAMNRLGSLLYQ-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces parvulus TaxID=146923 RepID=A0A369VBF4_9ACTN +-----ARLDAAFAEAGVTGWLHAVDVDSGAQV-EAGADQAVCTASVHKVCVLVTLHERAA +AGALDLTEQVECPPAGRTPGPTGLSAMLDPVMSLRDAAFWMMSVSDNTAADLLLRRV-GL +DAVNRTAERLGLTRTRAVYGFGEMLAALDPARTNRSTPRDMTRLLTAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Corallococcus llansteffanensis TaxID=2316731 RepID=A0A3A8PYN5_9DELT +---LNEGVEAAARDFDGALTLYVRDVRTGEEY-AFNASTPMYLSSAIKVAVMLEVLRQVD +TRTLALDRPVVFGPDDVRDMHPLAKVPSGTSLTVAALLDAMMVHSDNAAADLLIGQV-GI +DNVNAGLERRGVRFGPLVSLLEDRRHAYYVEGTNSAPMREVGRLLEQVARCVGLSPAACE +HAKALLRRCDTGRARIRAGLPDTAVWAHKTGTQHR-RACDVGLLEWEHGPSLVVAACARD +FR-RVSDAERLLARLGRTLARAf +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 218-10 TaxID=2486023 RepID=UPI000F78BC7F +-----------MGRLKGQNAVYVQQIGHDAYQ-WHV--KSQKAASDIKLFILATVYQQVQ +AGKFNLTATYTLKDGDKVGGTGSLQGMAAGTLTNQELLKYMMTVSDNTATNVVIREVGGF +DAVNREIKRLGATQTVLQRKMMDQKS-LAAGKDNMTSARDLGQLLAKLWQHQLISKSADM +AMLKLMAANTN-HSKLPKLIPSDRQVYNKTGEFDYGVENDAAIFAKGKRA-VVVVALSQG +GP--LAEQVAAMNQLGK------ +>[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. WMMA1423 TaxID=2591108 RepID=UPI00114729F5 +----PARIQAAFRAAGVTGFLHVVDMDTGREV-AAGADEPVVLASVFKVPLLVAFHRQAA +GGVLDPTEQVVLRPDDRTAPTGVSALLDEVRMSLRDLTCLMITVSDNAAADAVMDRV-GL +DAVNATAAELGLRRTVIEGNGRELHEALDPLRTSRSTPRDMTRLLSMIWRDEAAPPAGSA +AMRRLLGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGVVEYPDGARYAVAVFTRS +TLAVLPEADAVIGTAARIAVE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A649W0B8_ECOLX +--DVQQKLAELERQSGGRLGVALINTADNSQI-HYRADERFAMCSTSKVMAAAAVLKKSE +SEPNLLNQRVEIKKSDLVNYNPIAEMQVNGTMSLAELSAAALQYSDNVAMNKLIAHVGAP +ASVTAFARQLGDETF--------------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Asanoa hainanensis TaxID=560556 RepID=A0A239PBI1_9ACTN +---LAAKLQAIVDAAPVTAGVSVRDLSGEQQV-SVAGRFRPKAASLIKLWVITELMRRID +CGQAAYTDTVLVLPTDVVGGTGELQHTFPQNVTLFRLAQYTIKYSDNTATNVLIDYLGGF +GPVNALADSMNQTETVLARKMLA-----PAPPENFTSPDDVISLLGAVWSGNVLRQVNRD +LLLSFMLEQTL-NSKIPAALPSGVPVAHKTGELVD-VSHDVGYYLIPGT-EIAVAFLTAG +PE---ELGAETVRELARAVYDY- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. URHB0009 TaxID=1298866 RepID=UPI0004030CE6 +--------------SGARPGIEIV--AGQKHF-KYRAGEKFQAASLIKIPILIEAYRQSE +SGKFSLEDKAVINKDATSGGTGILKALSDGLVTIKDLMTLMITVSDNTAANILIDMI-GI +NELNKSFWEIGLENTVLERKMMDFTS-IEKGKDNFTTAIDIARCLKRVNEENYLSKANKV +DFLRILQMQQF-KSKLPALMDSKMYIGNKTGELPI-VEHDCAILHYGGV-SAYIAVLTDG +FREP-VEAKNAISRIGKHVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522SS50_9BACT +-kKLTKELEKTISGFHGTIGVYVWNLKNGKGA-AINADTLFPTASTIKVPIMCALFDKIV +KGGLSYRQPLLYLDSMAHGGSGVMQYFKDSTTDVSVAATLMMSRSDNTAAIWCQSLAGGG +TVINQWLADHGFENTRVNSRTPGRQKIWEIYGWGQTTPKEIADLVVDIREAKILNPAACE +RMYRNMTHQYW-DNVALSQISPYVQTASKGGAVD-AARSEVVLVNAPHGD-YVFAVYTKD +NKTPKNEAEVMIRKISALLWHYf +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E0H1A9_9CHLR +--SLEETVEKQLQSLDAQTSFYAKHLPSGKEI-SIRADQPMNPLSVIKIPMMILAFQDTE +NGQFDLDQRYRIRAEDMRGGSGLLQTFTTGLPTYRDLITQMIITSDNTATDIILNKL-TM +ERVNLFLEENGYLETIVKSSTGDLFRRFEGDSTGRTTAREMGMLLEQIENAELTSRKSAD +EMTNILKRQFY-SSRIPRFLRGKATVGHKTGDWPPHAGNDVAILYYDGG-PSIMAIFTNQ +NKGDFVELESTIGRIAEELVSRw +>[subseq from] serine hydrolase n=1 Tax=unclassified Facklamia TaxID=2622293 RepID=UPI0013BB4D08 +-------------NIKGKHQLYFRKVSENTAP-IVYNNQPARSASIIKLYILAVLFEQSE +KGMIDLNSMYSLQAADIVGGTGSIQNAPIGTYSLQQLAKEMIISSDNTATNILINELGGV +QFVNQQIHQMGFKQTQLRRKMLDFK-ALENGIDNETTVIDVGNLLTRLAQGELVSKSASQ +SMLDILEQQHD-HEKLFARMSKDIKVYNKTGTFERGVLADAGIMEYRNH-RYVFVVLSNN +GE--MTQQQQAMQKLG------- +>[subseq from] Beta-lactamase class A n=2 Tax=Microbacterium sp. SLBN-1 TaxID=1489561 RepID=A0A542GV67_9BACI +----REPMMRIVHECPGRVSFSVLT--NDESL-SWEENRQVSSASLIKLPILMAAYEQIQ +TGRLQADAMIGLRHEDHVGGAGVLNGLHEGLLSIEDLLTLMITVSDNTATNRLIDLI-GM +DSINRFCLEWHLKGTFLNRKMMDFRL-LDLGKDNWTSSMDVVSCLKGINEGPF-EETSRK +KMLTMLSHQQF-RDKLPALLGDDVKVFNKTGELP-GVEHDCALMESTSGKTAYVAVLIDE +LQ-DSEDGRRGIRKIGKLVYDY- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus yonginensis TaxID=1054041 RepID=UPI000F7708C9 +----------TMGHLKGQNAVYVQQIGHDAYQ-WHV--KSQKAASDIKLFILATVYQQVQ +AGKFNLTATYTLKDSDKVGGTGSLQGMAAGTLTNQELLKYMMTVSDNTATNVVIREVGGF +DAVNREIKRLGATQTVLQRKMMDQKS-LAAGKDNMTSALDLGQLLVKLWQHQLISKSADT +AMLKLMAANTN-HNKLPKLIPSDRQVYNKTGEFDYGVENDAAIFAKGKQ-AVVVVALSQG +GT--LAEQVAAMNQLGKQ----- +>[subseq from] Serine hydrolase n=1 Tax=Rufibacter glacialis TaxID=1259555 RepID=A0A5M8QC68_9BACT +-qKLTQKLQALTKDFQGDVGIYVRHLKTGQTV-AINADTLFPTASMIKVPIMVGVFDKME +KGELNPKTILRYRDSLYYAGEDLVGNFKDSSVALGKIQMLSITTSDNTASLWLQHLAGTG +TAINAWLEKNGFQHTRMNSRTPGRRPNWVKYGWGQTTPREMATLVTMIREGKAVSPAASE +RMYRNMGRIYV-DEVALSQIPPYVHTASKQGAVNQ-SRSEVVLVNAPHGD-YVFCIITKN +QKDEHNAGYDLIRAVSKTLWNHf +>[subseq from] serine hydrolase n=1 Tax=Nocardia takedensis TaxID=259390 RepID=UPI0002FF589F +---VEQRIRAVFADAGCTGWLHARRCDSPEEI-TVEGRSRVVTASVYKLPLFVAFCRLVD +VGRLDPRAPLTVVPAECTPPTGLAVLRDPVTMSRRDLATSMMTVSDNAAADVLLGEV-GL +GAVEDLLADLGLTETRVVGGTADQHRAYDPSYTSATTPEEMTRLLRALWSGAVLSVDQTE +FLASVMRRQPW-AHRISSAFPRGVSVAGKTGTIGV-IRNEVAVIEFPDEHPVAVAVFTRA +ARADLPAVDAAIAEAARLAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5NB57_9BACT +-eALRQACERIMSESKAAYAVALRDYETDFRF-AIHADRRFHAASTIKVAILLAIGKAID +DERIRPEDTLHVRNRFLSARTPFRHRLVGWTAKISDLAEWMIVSSSNLATNLLLDYI-TV +GEGQRVLREAGVSGVDLRRGVDDKK-AHDQNFNNETTASGLLDLFATL-RGDFLSKASRD +RAINILLQQRF-NSMIPAPLPAHASVAHKTGEIST-ACHDAGIVYLPEREPYILVVLTEV +FSET-NGRREAIAKISEAVFQ-- +>[subseq from] Beta-lactamase class A n=2 Tax=unclassified Armatimonadetes TaxID=1042316 RepID=A0A136L201_9BACT +-qALKPKLDAISKSFHGRLGYYVKRLDNGEEI-GIRDTERFPSASTIKTAIMVECFRQIE +RGELAWDERLETPPADKRSESMWVAFLAEGVINIDGLIHLMMNVSDNTATVMLADRV-GI +NSIEQLMLSWGLRDTACTIHVDEKDNRQIFANMGVTSPRDMGFLLEQIYRSKAASPAACQ +KMIRILSHQYW-DDFLSYAIPPTVGVASKVGALNR-SRSDSAIVFGP--RPYIVTVYTDH +QKEDDNEGNVAIRRISGLIWNH- +>[subseq from] Uncharacterized protein n=2 Tax=Armatimonadetes bacterium TaxID=2033014 RepID=A0A399XAA6_9BACT +-qALKPKLDAISKSFHGRLGYYVKRLDNGEEI-GIRDTERFPSASTIKTAIMVECFRQIE +RGELAWDERLETPPADKRSESMWVAFLAEGVINIDGLIHLMMNVSDNTATVMLADRV-GI +NSIEQLMLSWGLRDTACTIHVDEKDNRQIFANMGVTSPRDMGFLLEQIYRSKAASPAACQ +KMIRILSHQYW-DDFLSYAIPPTVGVASKVGALNR-SRSDSAIVFGP--RPYIVTVYTDH +QKEDDNEGNVAIRRISGLIWNH- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga sp. YR627 TaxID=1881041 RepID=A0A1I5I629_9BACT +-rKLEKGLKEIITGFQGEVGIYVRNLKTGRYV-DINADTIFPTASIVKIPILVGVFDKIE +KGELSYHQPLMYRDSIKYGGSGLMQFFKDSTTDLSVLVALMMAYSDNTTSLWNQALAGGG +QRINELMTQYGLNNTRVNSRTPGREAIRNVYGWGMTTPREMSELLVKIRKGEVISENASS +RMYRLMTHGYY-DEVGLSQIPPYTQAAHKSGSVD-ASRSEVILVNAPHGE-YVFYVGTKN +NKTNENEAENLIRKVSAYLWEHy +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium composti Yoo et al. 2007 non Ten et al. 2007 TaxID=415956 RepID=A0A5S5D6N7_9SPHI +--KLEKILQKEIDGFRGEIGIYVHHLGKNTTV-SLNGDTIFPTASIVKVPILVGVFQKVN +QQQLQLSDPFVYDTNRVYGGSGLMQFYKDSATDLSTMVSLMLTYSDNVASIWCQELAGGG +AEINRIMDSLGLKHTKVNSRTPGREDIWKKYGWGQTTPREIAQLMLLIRQGQVFTPRLSD +KMYRYLKNQFY-NERSLSQFPAHIATASKTGSVND-ARGEVVLVHGPSGD-FVFSVLTKN +NKTRDNEAENLTRKIANTLWNYf +>[subseq from] Beta-lactamase n=1 Tax=Hyalangium minutum TaxID=394096 RepID=A0A085WN07_9DELT +-------VEEVARDFEGELSLYVLNVEDGESY-AYDADTPTYLSSAIKIMVMLEVLHQVE +LQQLSWDELLELRPDDLRDMHRLGSARPGERLSIATLLEYMMGDSDNAAADLLIRRV-GL +DRVKAQLAARGIQTGPLTSLLEERQRSFYEEKVNSASMRDMGRLLAQVARCEGLSADSCS +RAHQLMRGCRTGRGRIAAGLPKTAAWAHKTGTQHR-RACDLGFLELRPGQTIVIAACTRG +FW-HVADAERLFARLGKLI---- +>[subseq from] serine hydrolase n=1 Tax=Haemophilus parasuis TaxID=738 RepID=UPI00136527BE +------------------------------------------------------------ +------------KKKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV +EQYQRILRQLGDNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT +ILWNWLDNNATGNPLIRAATPTSWKV---------------------------------- +----------------------- +>[subseq from] Possible beta-lactamase family protein n=2 Tax=Synechococcus sp. WH 5701 TaxID=69042 RepID=A3YY38_9SYNE +--KLSQRWKALAAQKDLKVGGFLLVLDDGRFA-QLNPDTPLPAASSIKTPILLAALDDLD +AGKLRWNEPLPLTKEVMGGGAGWMASRPGTRFPFYEAATEMIRVSDNSATNLLIKRLGGK +AATNAHFQALGLPATVVNNWLPDLDGT------NTTSPRDLARSIALVDIGEKLSPRARD +HFRTIMATSRT-NTLLPAGLLKGLTVLNKTGDIGI-AYADAGLIELPNGKRAVAGFMVKG +PFND-PRSTDLIRAMAAAVSQ-- +>[subseq from] Uncharacterized protein n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A645D0F9_9ZZZZ +---LNDVIKKCINDFNINCAVVVKNLNTGEEA-KVNEQMVMPAASIIKLFVMCEVFNNIN +KGKLFLEDKIIVKEEQKISYQLLTLFDEDREFTIRELLKLMICQSENTATNILIDMV-GI +DNINFFIKSLGFKNCEIQRKMLDMEAR-MQGKENYISATEVSKFLELLYNGEVINEKCSK +FMIDIMKSQLL-VAEVHRYIPDNIGLALKTGDVW-GYKHAAGIFYIDNCD-YVFTMLINY +KDDEIKFMDEFMGKMSAAVYNYf +>[subseq from] serine hydrolase n=1 Tax=Aquiflexum sp. Z0201 TaxID=2249427 RepID=UPI000DE8BE87 +-qSLQQVLEKEMAGFRGDVGIYVLHLKTGEEA-AINADTIFPTASIVKVPILVGVMDKIE +KRELAYHQKMIYRDSIKYGGSGLMQYFKDSTTELSVLMSLMITYSDNTTSLWCQALAGGG +ERINEIMESLGLKHTRVNSRTPGREEDWKKYGWGQTTPREMAQLLVKIRNGEVISPSVSD +RMYRLMGNIYY-DEYALSAIPAQVQTASKQGMVN-ASRSELVMVNAPKGD-YVFYFATKN +NEEDDNEAQLLQKRISKVLWEWf +>[subseq from] Serine hydrolase n=1 Tax=Flavihumibacter sp. CACIAM 22H1 TaxID=1812911 RepID=A0A162NN49_9BACT +-kKLEARLRQLTAEFKGEVGIYIKHLPSGKTA-AFQADTLFPTASMIKIPILLGIMQKIE +QKELAYHQPLIYRDSLLYAGEDILGSFKDGEIQLAKVIMLMMTTSDNTASLWLQSLAGTG +TEINRLLEELGFKYTRVNSRTPGRKENQQLYGWGQTTPKEMVELMERIYKGSLVSKEASD +RMLRIMGRNFW-DEEAISVHPPTIFIASKNGAVD-ASRSETLLVMAPKG-PYIFSIITKN +QQESSNEGWVLARKLADLLW--- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Candidatus Aminicenantes bacterium RBG_19FT_COMBO_59_29 TaxID=1797276 RepID=A0A1F5BD74_9BACT +---------------------AFRDLQTGEAL-FIKEKDMVHAASTMKVPVLIEVFKQAE +EGKFSLDDRVVIENESIVDGSSFTYGLIGTALTIRELAERMIIVSSNLATNILIELV-RP +ENVMTTLELLGVRRMRVMRGVEDSKA-FASGWNNQTDAYDLMLVLEAIASGRAGSLSSCQ +EMILILKKQKF-RNGIPAGVPGGVPVGNKTGSIT-GVEHDAAIVFPPGRRPYILVILTRG +VR--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Kribbella sp. ALI-6-A TaxID=1933817 RepID=A0A1V2NTP2_9ACTN +----NAQLRGIFDDAGARGWLHATSLDRPDEAiALDADHVVPMASVYKLPLVIAFAELVD +RGELDPREPITLRPEDRTPGPTGLSIFSDPVMSLRDLAASTMTLSDNAAADALLEIV-GL +DRVADFLRRQGLADTRIRRGTAGNLRVYEAANASATTARDMTTLLRALWSGELLSPDQTA +FVQRLMSLQIF-TQRIASAFPDAVRVYGKTGTFG-ALRHEVGVVELPGGPTVAVAVFTRA +ARADLPRVDAAIGQATRYAVD-- +>[subseq from] serine hydrolase n=1 Tax=Chitinophagaceae bacterium PMP191F TaxID=1691979 RepID=UPI0006BBA453 +-rKLQQKVEALLKDFDGQIGVYIKNLRTGKVV-MVNADTVFPTASMVKIPILIGIMDKIE +KGSLQYHQELEYKDSLLYAGSDILGSFKSGEIELGKVMMLMLTMSDNTASLWLQSLAGTG +TRINELMDSLGMQFTRVNSRTPGREENRIQFGWGQTTPREMATLFEKIYKGEVISKKAGQ +KMIRLLGRNYW-DEVAISQVPPDVFVASKNGAINQ-SRSETLLVAAPHG-HYIFSVCTKN +LSSSGNEAWTLERTLSALIWDYf +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7USP0_9BACT +------SVQALKRKHKERLGIALYDSETRVQW-SYNGDAFFHAASTMKLAVLVGVFRQVF +RKELGLETPVRVRNRSLVGGLPFSVARLGKTMNVKDLAYRMITTSSNFATNLLIDLV-TV +GVIHKALDELRVEGIEVLRGVDDQK-AFAAGKNNMVTADGLLKLLRLISDGRVYSPEISG +QLLEILLDQRV-KRGIPAGLPGGARVAHKTGHIST-VHHDAGIVYIGQRRPYAVVILTQS +PA--GAGGDAAVADASRQIYN-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000D50D346 +----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILTLTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVKKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-PYYAVVLIDG +LS-DNEQGRRLIADIGYLL---- +>[subseq from] serine hydrolase n=1 Tax=Fodinicola sp. GKU 173 TaxID=2681555 RepID=UPI0013D84C1B +-------LADLLDTADFRVGVAWLSLDGTPRL-LHHQDERFYAASTMKVAVMVAVHQAVE +RGELALTDKLPLTDRYVSVADGSTESYASGSATVEHLVEQMITVSSNEATNLLIAALGGV +AKAAEAQRRLSATGSQLQRPIGDLAAN-GTGLSNLVTAYDLAAGLGRLVSGQVAGPAATE +AMTATLCRQQR-VETIAAGLPAGTRWGGKNGWVD-GIRHDSGVVWPPDAPPYALAVCTAD +FGAD-ETAIALIRTVSARVYA-- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. XS-30 TaxID=2604421 RepID=A0A5B9WHD4_9BACT +-rKLEKALREIVNEFNGTAGVYVRHLKTGRYA-AVNADTIFPTASIVKVPILVGLFDKIE +KGELKYHQPLVYRDSIKYGGSGLMQFFKDSSTDISVLAALMMAYSDNTTSLWNQSLAGGG +AQINKLMEQYGLEHTRVNSRTPGREAIWKIYGWGQTTPREMSELVVKIFRGEVISPGASE +RMYRLMTKGYY-DEQAISQLPPYVQVAAKSGSVNE-SRSEVLLVNAPHGD-YVFYVGTKN +IKEPDNEAVAMIRKISALLWEHf +>[subseq from] serine hydrolase n=1 Tax=Nocardia sp. SYSU K10002 TaxID=2144174 RepID=UPI000D6939D7 +---VEDRIRAVFADAGCSGWLHARRCDSTGEI-SVDGHSRVVSASVYKLPLFVAFCRGVD +AGRVDPAARLTVLPSDCTPPTGIAVLRDPVTMSRRDLATSMMTVSDNAAADVLLGEI-GL +GAVEDLLADLGLIETRVVGGTADQYRAYDPSYTSATTPEEMTRLLRAIWTGSVLSHEQTD +FVRSVMRKQPW-SHRIASAFPRGVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLPVVDAAIAEVARIAV--- +>[subseq from] Serine hydrolase n=1 Tax=Balneolaceae bacterium TaxID=2053516 RepID=A0A651GCQ9_9BACT +--DLAIEITNYLNDKEGTYAVWFEHMQKEEAYfSINPDDMFHAASTMKTPVMVELFRRAE +LGEFNLADSIKVENRSIVDGSEFQERKVGEMATLYDLNHAMITYSSNITTNLILQLV-GA +EETTQTMRKLGAENIEVIRGLYDME-AFNRGLSNRTSARDLGIMFRHIASGTAVSPEMDS +LMVEVLKDQFY-RDVIPAKLPDDVVTATKSGFIT-GVIHDSGIVYLPDGQSYILIFLSKD +LP-DAAIGREAGAEVSRMIYEHf +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI000852D344 +--ELEKRLSAIIGQAEGTWGVVVEEQGKGTRF-EHVPDERFIAESVIKVPIMAAVFAASE +QGHFRLDDPLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK +AKIDQTMIDLGMRQSCYSRKLMIYPLD--ITENNKITAGDVASMLGQMATGSYLSEHACK +EMIAIMKKQQV-RNGLPSQLPNEWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD +VT--AQSALNTLGLLGRAVYDY- +>[subseq from] serine hydrolase n=1 Tax=Asanoa ferruginea TaxID=53367 RepID=UPI0011C1A71E +---LTARLQAIVASAPVTAGVSVRDLSGDQQI-SVAGRFRPKAASLIKLWVLVELMRRID +CGQAAYTDGVLVLPEDVVGGTGELQHETFPQVTLFRLAQYMIKYSDNTATNVLIDYLGGF +EPVNALIDSMNQRETVLGRKMLATP-----PPENFTSPDDVISLLGAVWDRQVLRQVNRD +LMLSFMLEQTL-NGKIPAALPSGVPVAHKTGELPD-VSHDVGYYLIPGT-EIAVAFLTAG +VE---TEGAETVRQLARAVYDY- +>[subseq from] Serine hydrolase n=4 Tax=Ruminococcaceae TaxID=541000 RepID=A0A3B9WE67_9FIRM +-eKLRQQIEQRLSAVTGDACFYYENLATGVCF-GHAADKPVVAASVIKLAVLIEAFRQMD +ADAVRANEMFVIARTDKLPSCGALNYLHDGLVTFRDLCVLMTILSDNTATNLLIKRL-GI +GNINDTLRMLGAEKMTLNRLLFDREA-SSRGIENYITAREAGLLLKRLYDGEAVSGPASE +DMLSILKDQRL-NGKIPFLLPHSVKIAHKTGEDD-GITHDVGIVYA--RQPFIVCFCGEH +V--SPPEFERAMQDITLMLYE-- +>[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus parabrevis TaxID=54914 RepID=A0A656ZM56_BREPA +--ELEKRLSEIVQEAEGIWGVVVKELGKGICF-EHQPDELFIAESVIKVPIMAAVYAACE +QGKARIEDQLPLRKEDLVGGSGFLYALSPGLLSIRDLVTLMIIQSDNTATNMLIDFV-GK +ELIDQTMRELGMERSYYSRKVMIYPQD--VTTNNMITAGDVARMLEHIVSGSGFSRAART +EMIAIMNKQQV-LNGLPSQLPPGWELACKSGWDA-GRQHDVGILFVEGR-QFAIAALSQD +VTPE--AALHTLGLLGRAVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7UJ48_9BACT +---LEKTVRGRLDALDAQSTLYAKHLATGREL-AIRADEAVNTVSVVKIPIMVLAYRDAE +AGRLSLDERHVITADEMRRGTGILQSAVGLNPTWRDLVTQMIDTSDNTATDLLIARL-GL +ERVNQMLEAMKYKETRLRMTIGQLFRGDPAKWFGRTTAREISRMLEQIQKGELAGPASTD +EMIRILKRQLY-FSRLPQRIRFRASVGHKTGDWPPIIGNDVGIIYSDAG-PIVVSVFTNQ +NRGRFFDLEAAIGKVAEDLLDAw +>[subseq from] serine hydrolase n=1 Tax=Nocardia crassostreae TaxID=53428 RepID=UPI00082E59D8 +--AIEERIRAVFADAGCTGWLHARRCDDSATEiSVGGGERVVTASVYKLPLFIAFCRAID +TGDIDPAARITVTPSECTPPTGIAAFRDPITMSRRDLATSMMTVSDNAAADVLLGEI-GL +PAIDALLTELGLTETRIVGGTADVFDAYDPSYTSATTPHEMTRFLTALWSGSVLSPAQTD +FTQIVLRAQAW-THRITSAFPRDIAVAGKTGTIGI-IRNEVAVIEFPGEIPVAVAVFTRA +ARPDLPAVDAAIAEAARIAV--- +>[subseq from] Serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=A0A2T2X1Y3_SULTH +--EAEKRIEDIVQAFSGHISFYAEHMQTHETL-TRDPDQVMETASVIKLPIMAATFQYLA +DEHKTLSEPLTLQVEDMVDGSGILQHLSPGLLSIKDVMTLMIIVSDNTATNMILRQV-GI +PRVNRFIQSLGLSQTRLLKRIDF---TIPG-PIGLATVRELGMILTQLYHRTLVNKDASD +VMWDILCRQQY-NTIMTRHLPPKVQIGSKSGSLE-GIRNDVGIITTPWGD-YVLAILSEH +SRHIDNEALVILPQLSRIIFDYf +>[subseq from] Uncharacterized protein n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5C2D056_9BACT +--ALAEELRAVADGFRGTLGYSFRHLRTGDEL-EHHGDEPFPTASTIKLALLCAAMDMQQ +RGEIGYEEERVLTEETRAYGTGFAQNYRAGTVELRELLHLMITASDNSATVMLGQWL-GR +EQVNRWLDRQDLRETRLLIPFPFGGTPFRQWGMGVTTPREMRLLLEMIVENRAGTPAACD +QMLRILGRQFY-DEGIASQVPPWVKVASKNGTDAR-SRSDVAVVHAPSGD-YVLAVYTKD +AERWDNEHATAIRAVSRAVWSHy +>[subseq from] Beta-lactamase class A n=1 Tax=Lactobacillus silagei JCM 19001 TaxID=1302250 RepID=A0A1Z5IHT4_9LACO +--------KKCLKKASGQTSIYVDSLNARQPV--IMNNRSQRSASVIKLFIMVETFRQIK +AGRLTLNQEVSIPQADRVGGTGELAHQSVSQLSVSRLLTLMIRNSDNSATNVLIDRLGGL +TVINQEINRLGCTQTRLQRKMLDYQ-ALKNGKDNLTSVKDVGGLLGKLYQHRVLGNPYDA +KMLQLLRYNAN-QSKLPALINQKATIFNKTGEFDYGVQNDAAIVQKGHQ-AFVVVVLSQH +GVQSK--QIN------------- +>[subseq from] Uncharacterized protein n=1 Tax=Pseudoxanthomonas suwonensis (strain 11-1) TaxID=743721 RepID=E6WP79_PSEUU +------------------------------------------------------------ +----------------------------------------------------------GE +PRLQALAAALGVPRAELGDSFEQVFEGYYARGLNSATLPAFGRMLERLAAGELLSPDSTA +LLLGHMRAITTGSRRIQAGLPPGADFAQKTGTQQQ-RACNVGILDPERGDGATVVVACAE +HFGELAQAEQAFQALGRAL---- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A2E8KVP4_9BACT +---------------QHEIGVAYLNLDSGDTF-YHSEKTVFHAASTMKTPVMFQLYRMRD +AGQLSLEDSLPVINESIVDGSPYSMRNINNKMAVRHLIEAMIATSSNLATNILIELA-DP +EAVMATLKETGADGVSVIRGVEDLKA-FDXGLSNRTDAYGLMMXMKAVFDSQLVSAKSRQ +EMIXXLKSQXF-NEMIPAGLPTGTSVAHKTGRIT-GITHDAAVVMPENDSPFVLVILTRG +WA--------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridia bacterium TaxID=2044939 RepID=A0A2V2FNY4_9FIRM +--KIKQIVEKYQRGTSAPLGVAFKDLRTGATV-TCHAEEPFPTASAYKIYVLAELYRKAY +SGECNLNDRYPLTVDIKSIGSGVLEQLDAGLLTLKDYATLMMIISDNTATDFLFNFLGRD +KIKKNVIDALGFSHTKCDWGCQKLIDQCVTEENDQTAPIEALKMLELLYRGTWVNQEASE +GMLAIMKQCQT-NTRIPHFLPPGVAVAHKTGSLDK-LNVDIGIVYAQPVGDYILCMFYNG +NLASKED---------------- +>[subseq from] Uncharacterized protein n=1 Tax=Rubrivirga sp. SAORIC476 TaxID=1961794 RepID=A0A271JB25_9BACT +------------------------------------ADRTFHAASTMKVGVMIEAFRQVQ +AGRRAWDDPVRVENRSIVDGTEYQYALQGRDVTFRTLTERAITTSSNLATNLLIGLV-TA +ESVQATMDRLGAPGLRVLRGVEDLKA-FEAGLSNATTADALATVLEAIRDGRAVSPAADA +EMVDILDDQAF-NEMIPAGLPAGTRVAHKTGWITE-IHHDAAIVYPEGAEPYVLVILTEG +LA-DHDESARLGAEVARAVH--- +>[subseq from] Serine hydrolase n=1 Tax=Bdellovibrionales bacterium TaxID=2053517 RepID=A0A3D3GBZ2_9PROT +--KLRKSLDQLEAAHPGQLGIYVKDPESGQSL-SLRGEEAWYIASGVKLPVAITLLQKFE +NDPISLDRKLQLSREDYLDGGGATNLQPPGRLSIRYLLEQMLIYSDNTASDLLIRHI-GL +NAVNNFVQEFAPDGFSGITRLADVRRLYYAQKLNTAKLSTYGVLLEKLVESKLFARESTR +LLLEILARTATGRQRLRAGFPGHYIFAHKTGTQFK-RACDFGISWSPKPRRLVIAACVRD +FK-TTREAETALKKIGQAIYS-- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus xiangfangensis TaxID=942150 RepID=A0A0R2MMD0_9LACO +-sQIKQDIASTVGSIGGTNSVYVSPVTSKQSV-LVNNGT-QSSASSIKLYILVTAYAMDK +EGVLNLDHTHTVTDDEKVGGTGVIQNMDAGTLTYREILAHMIDDSDNTAANIIIDKLGGF +SLINDKIASMGATDTKLRRKMMDTD-AISEGHDNTTSARDMGVTLKKIYNHQLVSKSADD +EMLAILAKNQN-RTKLPKLLPSEATVYNKTGEFDYGVQNDAEIVKNSHGA-FVAVVLSED +GDESD------------------ +>[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium UBA9857 TaxID=2060923 RepID=A0A3B9QE33_9FIRM +--KMADELEEICRK-TGVMGYSVRDLKTGRKA-GFREDVLFPTASTIKIHILLGVAIRVH +RGELDWAQRVVVEDKDKVGGSGVLGHFTYKALALRDVAALMISLSDNTATNICIDLA-TM +DLVNETMRSLGLTNTLLRRKMMDIEAAKRG-DENVSTPGELATLMAKIQERDGIPEAVAE +DVLSILSLPKTGP--FTLGLPSDIKRANKPGGLGN-LSVDAGVIYPTPDRPFALAVCGSF +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=UPI000307B9B4 +--EAEKRIEDIVQAFSGHISFYAEHMHTHETL-TRDPDHVMETASVIKLPIMAATFQYLA +DEHKTLSEPLTLQVEDMVDGSGILQHLSPGLLSIKDVMTLMIIVSDNTATNMILRQV-GI +PRVNRFIQSLGLSQTRLLKRIDF---TIPG-PIGLATARELGMILTQLYHRTLVNKDASD +VMWDILCRQQY-NTIMTRHLPPKVQIGSKSGSLE-GIRNDVGIITTPWGD-YVLAILSEH +SRHIDNEALVILPQLSRIIFDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter agarivorans TaxID=345907 RepID=A0A1I2JYX4_9FLAO +---LEQKLEELTASFKGDVGVYVKHLKTGKEA-AINADSIFPTASIVKVPILVKIFDKIE +EGELSYRDSLVYSEDRIYGGSGLMQFYKDSTTDLRTLVALMISYSDNVTSLWNQELAGGG +EAINKLMTELGLEHTRVNSRTEGRDKDWEKYGWGQTTPREMASILEQIRKRELVSAAASD +EMYRLLGNSFY-QDYALSQVPPYIQMAAKQGMVNK-SRSELFMVNGPSGD-YVCYIATKN +NEDDDNEAWQLQREISNLLWNYf +>[subseq from] Beta-lactamase (Modular protein) n=1 Tax=Syntrophaceticus schinkii TaxID=499207 RepID=A0A0B7MNK9_9FIRM +-rSLEDEIIDLTAQEQGTYGVYVIDLTTHQVC-GVNEDTVFHAASTFKLPLNIYLFQQIA +DGQIDPQTKLTYYSKHYEGGTGILQNKKYGSYTIQELAKYSIIYSDNVATNMLLGYL-GR +PNVKKMMADMGGIVV--D------NSA------NTTCPRDMALYMDALVEFNKEHPDQGA +ILLTHLKNTVF-NDRIPTLLPPDTEVAHKTGNWATGSYHDVGLVEHPSH-PYTIALFSKN +VS-SSAHAYHVLQRLSRLVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridium sp. CAG:594 TaxID=1262826 RepID=R6D3Y9_9CLOT +--------SEIEK--KEKVNILIKKVNCNETIfSYNENNVFVSASLIKVPIMLATLNEVK +NGNISLDKIITVSQDDILDDNEVFEKGK-YKYSVKELIYFMITVSDNTSTNILIKLL-GF +DYINKFIKEIGLYNTKLERYMNDWK-AIKNGKNNYTTLVDMNKCFEILINEDILNNELCN +FAINTLYGQKI-NNQIPRYIP-NVKFAHKTGGLDY-LNSDVGIFEKNG-EMYFIGISIYD +TPEKT-GDRKSTSILA------- +>[subseq from] serine hydrolase n=1 Tax=Microtetraspora niveoalba TaxID=46175 RepID=UPI0008366442 +-----RQLEQIFRTAGVTGWLHAVDIDTGREV-GLGADEPVVLASVFKVPLLVAFYRQAE +RGLIDPAERVTVSPEGRAGGTGVSAMLDEVTASLRDLAYLMISVSDNASADTLLARV-GL +DEVNAALADLGLSHTWVEHSCADLFTVLDPARTSRGTCRDMTRLLGMIWRDEAAGSASCA +AVRRLMGLQVW-PHRLASGFPDDVAVSGKTGTLPT-IRNEVGVIEYPDGGRYAIAVFTRS +IGQNQPRADAVIGTAARVAVDH- +>[subseq from] serine hydrolase n=1 Tax=Nocardia arthritidis TaxID=228602 RepID=UPI0014287267 +--EAQRRIADVFAAAGAEGNLHARALDSPAEI-GWAADEPVVLASVFKIPVALAYARQVA +AGALDPAERTTVTARDRIGGIGTAGCTDDVEMSWRDLAAFALTMSDNAATDVLLRRV-GI +DAVREVLAELGLHRTRLIGGCEDLFAVCDPARTTASTPREITALLAAIWQDTAGPAAACA +EVRAIMHRQIW-PHRLSSGFGDEVLIGAKTGTLPF-VRNEAGVLTFPDEKRYAVAIFTVA +AQANAPAIDAAIGSAARIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter echinorum TaxID=1073325 RepID=A0A1M5C3L1_9FLAO +-aKLQQQLEQLSQDFHGDVGIYVKHLKSGKEA-SLNADIIFPTASIVKVPILIKIFDKIE +KGSLSYNDTLVYTKDRVYGGSGLMQFYKDSTTDLRTLVALMISYSDNVTSLWNQELAGGG +KEVNELMVDLGLTHTRVNSRTEGREKDWEKYGWGQTTPREMASLLERIRERTLISATASD +EMYRLLGNSFY-QDYALSQVPPFVQAAAKQGMVNK-SRSELFMVNAPGGD-YVCYIATKN +NRDDDNEAWQLHRDISALLWNHf +>[subseq from] serine hydrolase n=1 Tax=Pedobacter nanyangensis TaxID=1562389 RepID=UPI000DE401D1 +--KLNKMVSALMKDFNGQVGIYVKSLKTGKIA-AYNADTIFPTASMIKVPITCGIFDKIE +KGELNYNTQLTYKDSLLYAGEDILGSFKNGEIWLAKVLMLMITTSDNTASLWCQSLAGTG +LAINELMGKYGLEHTRVNSRTPDRQANQRKYGWGQTTPREMASLLSLIREGKMISKAASE +RIYRNLIRIYF-DNVALSQIPPYVQVASKSGAVN-ASRSEVVLVNAPHGD-YVFCIITKN +QQDTDNEAEVLIRKTSKMLWNYf +>[subseq from] serine hydrolase n=1 Tax=Deinococcus frigens TaxID=249403 RepID=UPI0005520777 +------------RGYRGEVGLRVCDLAGAELL-TLNPERVFPAASTIKVPLLVLALEWAQ +AGRLALEERVTLGAADRVSGAGVLHELGPGLLSWRDVLTLMIIVSDNTATNLVIGVL-GV +EAVNDWLTAHGWTDTRLVGKLEQRNAAQLRNERNRTTALEQTDMLGRLVRGELLDAAHTA +LALNILERQQF-RDLIGRGLPRAYRLASKSGELD-GVHHDVGVLYTP--RPLVIALLTSG +GTD-------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. HMSC76G11 TaxID=1608910 RepID=A0A1S1FR37_9BACI +--NLELKLQEVMERCPGRIGLAL-DL-DGRII-ERNSNGIFSSASLIKLPILLTAFQQKE +RGILSFDEKVKMCDIEKTGGAGVLQSFSDDALTVSDLLSLMIIVSDNAATNYMIHKA-GR +PAINACMKDLNLTSTELNRDMMDLE-AIKNGLNNWTTADDMLKCLKAIGEYGFLPEVSRK +QIEDILQKQQF-TDKLPFHMKEKVYAGNKTGELP-GIEHDCAIIRFGDRT-AYAAVLIDQ +LQ-NKEAGRRTISEIGKFIYDE- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. T22 TaxID=2203219 RepID=A0A2Z3MTH9_9BACT +-rKMQQALQDIVSRFNGTAGVYVQHLKTGAWA-AIHADTIFPTASIVKVPLLVGLFNKID +KGELGYHQSLIYRDSAKYGGSGLMQFFKDSATEVSVLAALMMSYSDNTTSLWNQRLAGGG +VEVNRLMEQYGLKDTRVNSRTPGREDIWKIYGWGQTTPREMATLLIKIRRGEIISQDASE +RMYRLMCRGYY-DETALSQIPPYVQAAHKTGSVND-SRSELVMVNAPHGD-YVFYVGTKN +NKEPDNEAIEMIRTISAYLWKHf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID5606 TaxID=2690305 RepID=UPI00136F790F +-----ARLDAAFAEAGVTGWLHAVDVDSGAQV-EAGADQAVCTASVHKVCVLVTLHERAA +AGALDLTEQVECPPAGRTPGPTGLSAMLDPVMSLRDAAFWMMSVSDNTAADLLLRRV-GL +DAVNRTTERLGLTRTRAVYGFGEMLAALDPARTNRSTPRDMTRLLAAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. es.034 TaxID=1761763 RepID=A0A2A9BW36_9BACI +-nELEYKIREIMVRCNGRVSVAVELP--SHSF-HIDGDRSYSAASLIKIPILLEAFRQAQ +EGAISLNDMVTIPKEGRVGGAGVLVSLSDQLLTVEDLVTLMIIVSDNTAANLLIERL-GS +NAIQELCHTLKLKHTRILRKLMDFE-ALEKGLDNYTSALDIITCLKVVDIGKEYSQTNTG +KMLHILQQQQF-NTKLPSRMDEAVYIGNKTGELP-GVEHDCAIIKFRDKT-AYIAVLIDE +LGES-ETGKDTIAQIGELICD-- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E5UI11_9BACT +-tSLEETIEKQLQSLDAETSFYAKHLPTGKEI-SIRADQPMNPLSVIKIPMMILAFQDTE +NGQFDLDQRYRIRAGDMRGGSGLLQTFTTGLPTYRDLITQMIITSDNTATDIILNKL-TM +ERVNLFLEENGYLETIVKSSTGDLFRRFEGDSTGRTTAREMGMLLEQIENAELTSRKSAD +EMTNILKRQFY-SSRIPRFLRGKATVGHKTGDWPPHAGNDVAILYYDGG-PSIMAIFTNQ +NKGDFVELESTIGRIAEELVSRw +>[subseq from] Serine hydrolase n=1 Tax=Nocardia mangyaensis TaxID=2213200 RepID=A0A1J0W3A9_9NOCA +--------------------------DSGAEV-CVDGRDRVVLASVYKVLLLVAFCRRVE +DGTIDPTARLTIDPAECTPPTGLAALHDPVTLSRRDLATSMMTVSDNAAADVLLGEV-GL +AAMTELVDELDLTETRVLGGTADQHRAYDPSYASATTPEEMTRLLRRLWTGEVLSTASVE +FVRSVMGRQIW-PHRIAAAFPRGVLVAGKTGTIGV-IRNEVAVVEFPGETPVAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Niabella yanshanensis TaxID=577386 RepID=UPI000E0C750A +-kKLDVALKKEIAGFNGDIGIYVHHLKKNRMV-AINADTVFPTASIVKVPILVGVFDKIA +SGELKLSQEFIYDTSRLYGGSGLMQFYKDSATDLSTMISLMLTYSDNITSIWLQQLSGGG +MAINKMMDDLGLKNTKVNSRTEGRLEIWKKYGWGQTTPREMSKLFQLIREGKVIDARHSD +KMYRYLKNQFY-NGRSLAQFPSTVNTISKTGSVNE-ARGEVVLVNAPGGD-IVFCVLTKN +NKTDSNEAEVLTRKIAALIWNHy +>[subseq from] Class A beta-lactamase (Fragment) n=1 Tax=Coprobacter fastidiosus TaxID=1099853 RepID=A0A354M4K1_9BACT +-rELKMRIASVLKEKRAIVGVAVLY-GDNRLF-EVNRG-DYPMMSVCKFPLALAVLDYLH +KNNLSLDTDIFIRESDLLPYSPLRDRHPQGNMSIRELLSYTVSLSDNNACDILFGYIGGT +KVVDDYIKRLGISGMSVVATEAVMHESFEKQYCNTATPSSAVLLLDKFLKEDLLRDEYGN +YLRKIMIETSTGNDKIKAGLPEG------------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A5B8Q583_BACME +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILTLTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVKKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-PYYAVVLIDG +LS-DNEQGRRLIADIGYLL---- +>[subseq from] Serine hydrolase n=1 Tax=Blastocatellia bacterium TaxID=2052146 RepID=A0A353CAZ0_9BACT +-qSIDARVQAAIGDFKGKVWIYAKNLDTGKDY-GLRSDEQVRTASTIKLPIMTEVFRQVA +EGKIAWTDEIVISKQNKVGGSGILGEFTDGSIDLRTATNLMIVLSDNTATNIVLDKV-TS +NAVNDHMAKLGLKDTLSLRKVGGGGDAKAYDEPGRSSPKDMVRLLEMLERGEVVSKEASA +EMIAILRRQQY-KDGIGRNALDTVPVASKSGSLDR-LRSDVGIVYTRRG-RIAMAITVDD +M---------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=A0A1J6WVK7_9BACI +---LEEQIHELIEGVEGRISLYIEL--PAHTL-KMNSDVPYSAASLIKLPILLEGFRQIQ +EKKLELDEVIPVTPEDKVGGAGVLSHLSPHTVTVHDLLTLMIIVSDNTASNLLINRM-GM +DSVNGMCRLLGLEQTKLNRRLMDFE-ALEMEVDNHISATDAVKCLKAMENDDLFQLNSRE +SMLRILQNQQF-YQKLPGSMDRNVVTANKTGELP-GVEHDCAIIRYKHQ-TIYAAVLIDE +LK-DSSEGSGLIMKVGKCLND-- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus aryabhattai B8W22 TaxID=1358420 RepID=A0A1G6PMJ4_9BACI +-----------TKWKQSNNGLIRIHIEGKESI-RINSFIQQRAASTIKLLLAIEAFRQID +EGILTLTSVIQRTEKNTVGGAGVLGALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECARNMGLKKTVLNRYMMD-ETAVKQGLDNYTCASDVVECLREIYEGNLLKKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LSEN-EQGRRLIADIGYL----- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides xylanolyticus TaxID=384636 RepID=A0A2S6HMV7_9BACE +----RDEIIRILDQVPGKISFLYENLETGERV-GYREDQPLMAASVIKLYVMAAAFNQFE +TGKLRQDFSLPIYKKDCVPCGALTYLHEGICVTALDLVTLMIIFSDNTATNLLIELL-GM +EEINQYIKSLGFEKTCLNRKMYDTEKS-SKGIQNYITASETGRLLMMMYRGELVSEGASR +QMISILKNQQL-CSKIPFYLQEEPEIAHKTGEDR-GITHDVGIVYGK--TPFLVCF-CGN +ET-DTPGFERIMGELS------- +>[subseq from] Beta-lactamase class A n=1 Tax=Niabella drilacis TaxID=1285928 RepID=A0A1G6WUT6_9BACT +-kKLKVLIEKAVSDFHGDIGVYVHHLKKNKSV-ALNADTVFPTASIVKVPILAGVFNKIA +KSELKLSQEFVYDAKREYGGSGLMQFYKDSATDLSTMISLMLTYSDNVASIWLQELAGGG +VAINTIMDQLGLTNTKVNSRTTGRQDIWKKYGWGQTTPKEMAQLFTLIRQGKVVNARYSD +KMYRYLKNQFY-NGRSLSQIPATVNTICKTGSVDD-ARGEVVLVNAPGGD-IVFCILTKN +NKTDDNEAEILTRKLAHIIWNYy +>[subseq from] Serine hydrolase n=1 Tax=[Brevibacterium] frigoritolerans TaxID=450367 RepID=A0A4R6AC18_9BACI +---LKLKLQEVIDRCPGKIGLAIVL--DGEII-EWNSNGIFSSASLIKLPILLTAFRLKD +RGILALNEKVNLRDIEKTGGAGVLQSFSDDALTVSDLLSLMIIVSDNAATNYMIYKA-SR +PAIHACMKDLNLTSTELNRDMMDLE-AIKNGLNNWTTADDMLKCLKAIGEDGFLTEVSRK +QIEDILQKQQF-TDKLPYHMDDKVYAGNKTGELP-GIEHDCAIIRFGDRT-AYAAVLIDQ +LQ-NKEAGRRTISEIGKLIYDE- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A5C8DKR3_9BACT +-kKLEAELRKAITGFNGAIGIYVKNIKTGETV-AINADTVFPTASIVKVPIMMGVMDKMQ +KGELHYDSTHIYKDSLLYEGEDILGSFKDGEIALKKIIMLMLTTSDNTASLWLQKLAGTG +TRINALMDSLGYINTRVNSRTPGREEIRKIYGWGQTSPAEMGRLFEQIYQNKLFTPAACE +RIMRCLGRNFWDEDEAISMIPPYIEVFSKNGCVD-ASRNEALLVNAPNR-PYIFCIFTKN +NKTHANEAWTLTRKISSLLWDYf +>[subseq from] Serine hydrolase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A429A4Y6_9ACTN +-----ARIHAAFADAGVTGRLHAVGIDSGVQL-DAGADRPVPTASVHKLCLLVALHAQDA +AGRLDLTEQVECLPADRTAPTGVAAMLDTARLSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTARLGLTRTRAVHSFGEMLAALDPARTNRSTPRDLTRLLAAVWRDEACTPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Flexithrix dorotheae TaxID=70993 RepID=UPI000475640C +-qKLANEIKKTFAEVKGDFALAYISLDNPSDSlLINAYEEFHAASTMKTPVMIEVYKQAN +EGKLNLDDSIMIYTRSIVDTSTFIEKLFEKEWPLRDVMYKMIIESSNLGTNLLVEMV-DA +KNITQTMRELGAPKINVLRGVEDIK-AYRKGLSNSTTAYDLMKIFEGLGNGTVVNKDASE +EMIDILLDQKY-NEIIPAKLPQDVKVAHKTGWIT-GVHHDSALLMLPNGKKYVLVLLSKN +LE-DEAKGVEALATASKLLFDY- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536AU30_9CHLR +----------ALATLPGEAAAFASDADGHALF-CEREDELFPSASVIKLPLVMTLYADAT +RGLIDLDERVAVG--DRVDGSGVLRHMRDVELSLRDLAMLAIIVSDNTATNRLIERI-GV +DRVGERLREWGCPKTRLSRKMYDFEAA-KRGHENVMTARETVSLLVRLQRGECEDRATSD +AVLAVLEQCQD-RTMLLRYLPYGAKVPHKTGTLDE-SRNDAAIV--PGERPVIVAGFTRK +LRDT------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter holothuriorum TaxID=241145 RepID=A0A1T5D4L3_9FLAO +--ELQQKLEALIDDFKGEVGIYVKNLETGKEV-AINADTIFPTASIVKVPILVKIFDKIE +KGDLNYNDTLVYSSDRIYGGSGLMQFYKDSTTDLRTLVALMISYSDNVTSLWNQELAGGG +ESINKLMAELGLEHTRVNSRTDGREKNWEKYGWGQTTPREMASILVEIRNRELISPAASD +EMYRLLGNSFY-QDYALSQVPPYVQAAAKQGMVNR-SRSELFMVNAASGD-YVCYIATKN +NKEDDNEAWELQREISALLWKYf +>[subseq from] Serine hydrolase n=1 Tax=Lentzea guizhouensis TaxID=1586287 RepID=A0A1B2I047_9PSEU +---VADRIREAFAEAGTEGFVHAREVQDGPEV-GVGADDPVVLASVFKIPVAVAFAAEVA +AGRLDDTQRTRVTSRYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDVIFHRV-GQ +AAVDAVLANLGLHRTRIMGCCEDLFAIVDPERTTSSTPREITTLLDAIWTGRAAAPQACE +RVRSIMAQQVW-PHRLSSGFPADVQVAAKTGTLP-GVRNEAGVVTYPDGRGYAVAVFTRA +ESLRQPAVDAVIGRAGRLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI000A11294B +----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD +AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. WAC 01424 TaxID=2203200 RepID=A0A429AGQ7_9ACTN +----ERDAQKVFAAAGVRGFVHARDVDGEAET-GLDPDAPVVLASVFKLPILLEYARQAA +AGEVDRTERLTVTEADKDGGIGTSGCADDVSLTLRDLAHFMMSMSDNAATDVLLRRV-GL +DRVNATLEHLGLRRTRLIGGCATLFEVRDPQRTTAGTPREITTLLGLVWRDEAGPAEACA +EVRDIMSRQIW-PHRLSSGFPDEVRVSAKTGTLW-GVRNEAGVVEYPDGGRYAVAVFLHG +DNFRMPAADAAIGEAARLAVEH- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI00119FA2F7 +----------------------------GVDI-GVGADDPVVTASVYKLPLVVAFCRLVD +AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI000A10CB05 +----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD +AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRI-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus marmoris TaxID=249408 RepID=UPI000496ADCA +------------QGYVGEVGLRVCDVLGRELF-ALNPERVFPAASTIKVPLLILALEWAQ +AGRLDLEGRVTLQAADRVPGAGVLHELGSGLLSWRDVLTLMIVVSDNTATNLVIEQL-GM +DAVNGWLNAHGWTDTRLVGKLEQRNAAQLRGERNRTTAREQTDILGRLVRGDLLDAAHTA +LALDILERQQY-RDLIGRGLPRAYRLASKSGELG-GVHHDVGVLYTP--RPLVIALLSEG +GM--------------------- +>[subseq from] Beta-lactamase class A n=2 Tax=Arcticibacter pallidicorallinus TaxID=1259464 RepID=A0A2T0U4G0_9SPHI +-hKLEKALSRLVDTFKGSVGIYVMNLRTGKYA-SLNGDSIFPTASIVKVPILVGLFDQIE +QGKLSYHQPMIYRDSIKYGGSGIMQHFKDSSTEVSVLAHLMMSYSDNTTSLWNQQLAGGG +EQINKLMDKYGFPNIRVNSRTKGREEIWKKYGWGQSTPREMASLLVKIRNGEIVSKAASD +RMYRLMTKGYY-DEDALAQIPPYVQAAAKSGAVD-ASRSEVVLVNAPSGE-YVFYVGTKD +NADQDNEGQVLIRKVSACLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535RNZ9_9CHLR +------ALERHLDALRGRAGVFICEADETARF-SRDADEIFPAASVIKVPLVMALYADAA +RGAVDLEQCVGVGE--RVAGTGVLARLRDVHLTLRDYAMLTIMVSDNMATNRIIDRV-GI +EVVNAYLDRWGCPRTRLRRKMFDLDAR-AKGLDNVMTPRESAHLLAMLVRGELVDRATSD +AVLELLAATMY-DGKARRYLSGDVSTANKTGRLD-GVRNDIAIIRVS--RPVILAAFTRD +LARES------------------ +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI00119F663C +----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD +AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI000A102822 +----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD +AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] serine hydrolase n=1 Tax=Verrucomicrobia bacterium SCGC AAA168-F10 TaxID=1009423 RepID=UPI00056E8994 +---LASKLETRVAELDGEVGLYVYHLETNHSV-LINADELFPAASMIKVPILASLLNKVE +RGELGYQDKLTYTKDRLYPGEDLLGSFANNELTLKKLVFLMITTSDNTASLWCQELAGTG +TTINTWLKKKGFLRTRLNSRTPGRVTAQDRYGWGQTTPREMAQLLIRIRNRKLVSAAADE +EMARVMGRIYWDGEAI-SSVPPSIATISKQGAVN-ASRSEVVLVHAPHGD-YVFCVITKN +QKKHDNQGFSLLRDISRILWEHf +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga rupis TaxID=573321 RepID=A0A1H8DJF8_9BACT +-kQLTALLRPYLEKHHGVAGIYVHHLKKDKYV-AINADTLFPTASTIKMTIMVGIFDKIA +KGELQYHQPLVYKDSLLYAGEDILGSFKSGEITLDKVMMLMLTMSDNTASLWLQSLAGGG +QQINAWLEAHGFVNTRVNSRTPGREANRTALGWGQTSPREMARLMEMIYKGEVVSKAASE +RMYRNLTRNYW-DQEGLLEFPKEVRTASKNGAVD-GSRSEVVMVSAAHGD-FVYSIYTKN +NLERNNEAWQLLRQVARTIWNYy +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. KSM4-11 TaxID=2568654 RepID=A0A4S4CF89_9DEIO +------------RGFTGSVGLSVTTLDGTVRV-ALNADQVFPAASTIKVPLLLLALERAQ +AGQLDLTARVVMDASDRVTGAGVLHDLSGGLLTWQDVLTLMIIVSDNTATNLVIGQL-EV +NAVNAWLDAHGCGATRLVGKLEQRNEAQQRGERNRTTAREQTELLGRLVRGELLDAAHTA +LALDILSRQQH-RDVIGRRVPPRYRLCSKSGELE-GVHHDVGVLYTP--APLVVALLSEG +GT--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. SDF0063 TaxID=2133753 RepID=A0A544UPP2_9BACI +--ELEKRLSAIIGQAEGTWGVVVEEQGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE +QGHFRLDDQLVLRQEDLVGGSGLLYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK +DQIDQTMIDLGMHQSCYSRKLMIYPLD--ITENNKITAGDVANMLGHLATGSFLSQRACK +EMIAIMKKQQV-RNGLPSQLPPGWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD +VT--AQSALNTLGLLGRAVYDY- +>[subseq from] Beta-lactamase n=1 Tax=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) TaxID=485917 RepID=C6Y376_PEDHD +-hKLEKELNTLISGFKGTVGIYTMNLKTGKQA-GIYTDSIFPTASIVKVPILIGLFDKIE +KGELSYHQPLMYRDSIKYGGSGIMQFFKDSSTELSVLANLMMTYSDNTTSLWNQRLAGGG +ARINEVLEQYGFKDTRVNSRTKGREAIWKIYGWGQTTPREMATLLVKIRKGEIISKAASE +RMYRLMTKGYY-DENALAQIPPYVQAAAKSGAVNE-SRSEVVLVNAPHGD-YVFYVGTKN +IKTPDNEAEQLIRKVSALLWKYy +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI0007CD6BCC +----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD +AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] Putative beta-lactamase n=1 Tax=Rhodococcus hoagii (strain 103S) TaxID=685727 RepID=A0A3S5YBS1_RHOH1 +----------------------------GVDI-GVGADDPVVTASVYKLPLVVAFCRLVD +AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] serine hydrolase n=1 Tax=Frankia sp. Iso899 TaxID=1283283 RepID=UPI0009DBAED2 +-----SNIKEEASKIGARVFAHAIDIDTGVDA-GIDAEHPVVTASVFKVPVLAEYVRQVS +IGDLDPRTRIVVKAADATPGPTGLSVFNDDAWSLRDIATSMITVSDNTATDIVCRLV-GI +DRVNALMESLGLSGTKLVGDCVDTFAICTPSATNRTTPRDATRLLELLWTDKVASPDACA +QARAILGKQVW-THRLSSGFPDDIRVSGKTGTIGI-VRNEIGVVEYPDGRRYAVAIFVRT +GEYRNPAADRLIGTAARLLVD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. FJAT-29937 TaxID=1720553 RepID=UPI00082CEA8E +-dNLKRQVSELVAHCEGRVGLVIETCEGR--I-EINHNDKFSAASLIKIPILIEGFRQCE +KGLLDLHEYLLALPSNRVGGAGVIQALSADLLKIIDLMALMIIVSDNSATNLVIDRV-GM +TEINECIKALNLQNTELNRKMMDFEAK-KNGLDNFTTANDMLTCLKVIDQHRFLSKESSD +KAFSILEKQQFKNKLAETIDSEAVQVANKTGELP-GVEHDCAIFKYGGK-TIYAAVLIDQ +LS-SQEEGKQTLVQIGKVL---- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI0009C00809 +----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD +AGDLDPREQVTLDPSTRTAPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Marinamargulisbacteria bacterium SCGC AG-439-L15 TaxID=2184346 RepID=A0A328RGS4_9BACT +-qQLRQTLQQYSDTQNTTVSLVYMSTNSSESV-ALNPRLSVNPASVIKVPILIEAYRQLE +MGRLKKGQLFEMKKEHLQKGAGRLKYHALGTYTIHDLLYHMIVNSDNTATKMLIAIL-GQ +SRINEGIKRLGLRDTYLHTDN--L---LTGQPKNKASAYDMALLLHKLYRGEVISKGASD +EIVRLLSKQKY-RWGIPQQLPKKLRVANKTGSLRW-VSHDVGIVFFPDA-PYILSIFVSD +IKTT-LQARKQVAKLSQIVYQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Parabacteroides johnsonii DSM 18315 TaxID=537006 RepID=B7BEE4_9BACT +-kAIENALQEYIKGKDARIGIAII-INGKDTV-SVNGNRDFPMMSVVKFPLALTVANWVD +TNNMSLSDTVTFSGKSLKEYSPMLKKYGKSRMTVRELLEWSLVESDNNAADILLNCVGGV +SGATSKMRQIGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFNNEMRNASQSYS +EISVMLKQCRTGLDRLALLLPTNATIGHKTGTGF-------------------------- +----------------------- +>[subseq from] Serine hydrolase n=2 Tax=Fibrella sp. ES10-3-2-2 TaxID=1834519 RepID=A0A1W6E180_9BACT +-tKLTQKLTEALRGFRGDVGVYVHHLKTGKTV-AINADTTFPTASTIKIPIMIGLFDQIE +KGKIGYQQEVVYRDSLHYDDGIVGSLKDGAKLSLSEVVMLMETVSDNTGSLWCQKLAGGG +IAINAWLDTNGFPQTRMNSRTPGREAYQKRYGWGQTTPRELADLLTYLRQGRAISPDASD +RMYRNLCRQFW-DNDGLSQLPVEVKVACKTGAVNQ-ARSEVVLVHAPHGE-YVYCVMTKN +QKDETNEGFTLLRTVSALIWQHf +>[subseq from] serine hydrolase n=1 Tax=Nocardia mangyaensis TaxID=2213200 RepID=UPI000A01A774 +--------------------------DSGAEV-CVDGRDRVVLASVYKVLLLVAFCRRVE +DGTIDPTARLTIDPAECTPPTGLAALHDPVTLSRRDLATSMMTVSDNAAADVLLGEV-GL +AAMTELVDELDLTETRVLGGTADQHRAYDPSYASATTPEEMTRLLRRLWTGEVLSTASVE +FVRSVMGRQIW-PHRIAAAFPRGVLVAGKTGTIGV-IRNEVAVVEFPGETPVAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Serine hydrolase n=2 Tax=Ruminococcaceae TaxID=541000 RepID=A0A0W7TVI8_9FIRM +-eKLRQQIEQRLSAVMGDACFYYENLATGVCF-GHAADKPVVAASVIKLAVLIEAFRQMD +ADAVRANEMFVIARTDKLPSCGALNYLHDGLVTFRDLCVLMTILSDNTATNLLIKRL-GI +GNINDTLRMLGAEKMTLNRLLFDREA-SSRGIENYITAREAGLLLKRLYDGEAVSGPASE +DMLSILKDQRL-NGKIPFLLPHSVKIAHKTGEDD-GITHDVGIVYA--RQPFIVCFCGEH +V--SPPEFERAMQDITLMLYE-- +>[subseq from] Beta-lactamase class A n=2 Tax=Vibrionimonas magnilacihabitans TaxID=669455 RepID=A0A2S8SGI9_9BACT +-qRLQQQVTQLLKGFNGDIGIYVHDLKRDRIV-SINADTVFPTASMVKVPILTGIMDKIH +RKELDYHQVLTYKDSLLYEGVDILGSFKNGEIELSKVMMLMLTMSDNTASLWLQTLAGKG +TRINELMDSLGLKVTRVNSRTPGREANRNMYGWGQSSPREMASLMEMIVKKQVIGDSTSQ +MMLRLLGRNYW-DENAISQIPSDVFVASKSGAVD-ATRNEVLFVNGKKC-SYVFCICTKN +NKESTNEAWVLTRKLSKLLWEYy +>[subseq from] Beta-lactamase n=2 Tax=Chroococcidiopsis thermalis TaxID=54299 RepID=K9U3H5_CHRTP +------DFQPLVANFQGTTGIIIKTLDSGSCF-QFNPNLVFPAASLIELPILWEFFHQCA +TGSLDLAEEIELQSEDMVIGFGILRQLKPGLLCLYDLAVLMTVVSDNTATNLLIDKL-GI +DNINDSIQRIGLTHTILQYKMYDSIS---TSQDNLTTPSDMLRMLEAFIQDKHLLSKYGD +EPLKILEGQQC-KNKLHLGIPKGARLANKTGETL-GTEHDIGVLLGREE-TVIIVVMTTG +LSEN-YQGIELCRDVARLVYQ-- +>[subseq from] Uncharacterized protein n=2 Tax=Bacillus sp. Leaf406 TaxID=1736368 RepID=A0A0Q6L9X1_9BACI +-kDLREDLMKIVHECPGSVSFTILS--NDESL-SWEENRRISSASLIKLPIMMAAFEQIQ +TGSLKGDAMVVLRHEDHVEGAGVLYGHDGITLSIEDLLTLMITVSDNTATNQLIELI-GK +DSINRFCLSWKLKRTFLNRKMMDFRL-LEMGQDNWTSSMDVVSCLRGINEGPF-EEASRR +KMLMMLSRQQF-RDKLPALVGGDVKVFNKTGELP-GVEHDCAILESTSGKIAYVAVLIDE +LQVP-EDGRMAISRIGKLVYDY- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Caulobacter TaxID=2648921 RepID=A0A318ASS1_9CAUL +--TLNPRLAALAERAPGILGVAAQDLTTAQRI-ATAGDRPFPMDGVWKAALGAAVLSEIE +AKALSPSEILTIEDVDLSPPGAVADAWPAHGYTVEDLFKRAVALSDNTAADVLLKRIGGP +GAVTAWLELRKVEGVRLDRYARQLLPRYLADPRDTATPLGAVRFLEALNQFELTSQDGRG +RLLRLMEAAA--GDRLRPALPAGARLAALTTWTPYDADATLAMVQMQDGRRFALAIFLKA +SPLEDEDRTALIVDIARTVL--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces canus TaxID=58343 RepID=UPI0007501FB8 +--AVAARLDAAFADAGVTGWLHAVDIDSGAQV-EAGADQPVCTASVHKLCVLVTLHERAA +AGELDLTERVECPPDGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGETLDALDPARTNHSTPRDMTRLLGALWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AQAVLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. E5N298 TaxID=1851983 RepID=UPI000EF59F95 +--AVAARLDAAFADAGVTGWLHAVDIDSGAQV-EAGADQPVCTASVHKLCVLVTLHERAA +AGELDLTERVECPPDGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGETLDALDPARTNHSTPRDMTRLLGALWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AQAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. M1013 TaxID=549798 RepID=A0A1R1WM30_9ACTN +--AVAARLDAAFADAGVTGWLHAVDIDSGAQV-EAGADQPVCTASVHKLCVLVTLHERAA +AGELDLTERVECPPDGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGETLDALDPARTNHSTPRDMTRLLGALWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AQAVLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Dyadobacter jiangsuensis TaxID=1591085 RepID=A0A2P8G408_9BACT +-kKLTAQLEAALAGFHGQVGVYVRNLKTNRIA-AVNADSLYPTASMVKVPIMCGIFDKIE +KGEITFNQELVYRDSLKYDNGIVGSFRDSTKIALPKVVHLMISQSDNTGSLWLQAMAGGG +TAINQWLDGNGFANTRVNSRTPGRKEFQARYGWGVTTPREMAELVAMIRNGKAVSPAASD +RMYRYLGMQFW-DDEAISQLPSNVKIAAKSGAVNQ-AKSEVLVVHAPHGD-YVFCIATKN +QEQKDNEGYALIRKVSAIIWKHf +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus nasuensis JCM 17158 TaxID=1291734 RepID=A0A0R1JGN7_9LACO +---VTTPLTQAVAGLAGTTSLYLGDPATGQTWtYHNGPQR--SASTIKLFVLGAAFAQAK +AGRFALNATYVLQASDKVGGTGTIQGLPAGTLTRQALLTKMIQVSDNTATNIIITQLGGF +GVVNAFARSIGATHTVLARKMLDTA-ALARGVDNRTTVADTGLLLTKLANHRLVSASADS +AMLTMLAGQTN-RSKLAAGAGSGITVYNKTGEYDYGVENDAAIFRRGQRQ-RVIVMMSQG +GTLS--AQIPAFNAVGRLV---- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI0003B1E9A4 +----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD +AGDLDPREQVTLDPSTRTTPTGISQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. AK5 TaxID=2587159 RepID=UPI001153496F +--SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEACPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus pimensis TaxID=309888 RepID=UPI0004B197E3 +--------------HPGRVGVTVHDLATGELLfAHDADHVYHAASTIKVPLLIRALQRVA +AGDLRLTDRHVMLAGDQVGGAGVLHELSPGLLTLRDLLTLMIVVSDNTATNMVIDRV-GL +DDVNAFLAEAGLRDSALVGGLQLPPERQRAGERNRTTARDMGRVLLGLARGAYLPDDLNE +LALGILSRQQY-RDVIGRGLPTDYRVASKSGELL-GVHHDVGLVWTP--RPLAVAVLSEG +GL--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Deminuibacter soli TaxID=2291815 RepID=A0A3E1NCT0_9BACT +-kKLEGMLKAVADSFHGVAGIYVHNLKTNREV-AINADTIFPTASIIKVPILVGMFDQIQ +QGTYKYHTPLVYRDSMSRKGSGLMQFFKDSTTDVRTAITLMITHSDNAAAVWCERMAGGG +STINTWLDAHGFKDTRLNARTPGRETARQQYGWGQTTPREMAKLAAMIRNEQAVSPEASQ +TMYRIMTHSFW-DEYALFSLPPYVQAASKQGMVDD-SRSEIVVVNAPHGD-YVFYVATKN +NKVEDNEAWQLARKVSAMLWNYy +>[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7Q974_9BACT +--SLSDKLSLLIKAHQGKVAIGLKNLTTGETY-YHQGDLVMPTASLIKLGVMATAYRLSD +QSKIGLNDMVLLQKEDKVPGSGILTSNFTEGFPLKDAIRLMIAYSDNTATNLVLDHI-GI +RTVNTTLAQMGLPNTRINAKVFKGSTQTKKYGLGSTTAKETIDLLELIYINKAATETSCK +AMIEHLKKCEN-KDMIPRELTKLKSLAHKIGAVSD-ARTDAGILYFDGG-PVVLCVLTTE +NMTSENSAEILIGKIGLSVFEHf +>[subseq from] Class A beta-lactamase n=1 Tax=Brevibacillus sp. NRRL NRS-603 TaxID=2126351 RepID=A0A2P7WHS2_9BACL +--ELENRLSAIIGQAEGTWGVVVEEQGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE +QGHFRLDDQLVLRQEDLVGGSGILYALSPGLLTIRDLVNLMIIQSDNTATNMLIDLV-GK +AQIDQTMIDLGMRQSCYSRKLMIYPLD--ITENNKITAGDVASMLGHLAKGSYLSQRACQ +EMIAIMKKQQV-RNGLPSQLPPGWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKN +VT--AQSALNTLGLLGRAVYDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga niabensis TaxID=536979 RepID=A0A1N6J2L7_9BACT +-hKLEKALAELTQGFNGTAGVYVLNLKTGKYA-SLNGDTIFPTASIVKVPLLVGLFSKIE +KGELGWHQALVYRDSAKYGGSGLMQFFKDSSTEVSVLAALMMAYSDNTTSLWNQQLAGGG +EEVNKLMEQYGLKDTRVNSRTKGREEIRKIYGWGQTTPREMSALVAKIHRGEVISKAASE +RMYRLMTKGYY-DEQAISEVPPYIQVAAKSGSVNE-SRSEVVLVNAPHGD-YVFYVGTKN +IKEADNEAVVMIRKISAYLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. p52 TaxID=935199 RepID=A0A1B2UCV7_9NOCA +----------------------------AATL-SVRGDERVVLASVYKLPLFLAFCAEVD +AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT +TTVEKLLARLGLTRTRIIGGTADVYQAYDPAYTSATIPEEMTRLLEAVWSGSVLSPESTA +FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus pyridinivorans SB3094 TaxID=1435356 RepID=V9XLG3_9NOCA +----------------------------AATL-SVRGDERVVLASVYKLPLFLAFCAEVD +AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT +TTVEKLLARLGLTRTRIIGGTADVYQAYDPAYTSATIPEEMTRLLEAVWSGSVLSPESTA +FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces coelicoflavus TaxID=285562 RepID=UPI0013B97E07 +--ATAARLDAAFADAGVTGWLHAVDVDSGAQV-GVRADQPVCTASVHKLCVLVTLHELAA +AGALDLTEQVECPPDGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL +DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRNEAAPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus brevis TaxID=1580 RepID=UPI00046345D7 +--EIKKDIGATVGAIGGTNSVYVSPVNSEQSV-VV-NNGSQRSASSIKIYIMVTAYAMAK +EGVFNLNDTHTLTNDEKVGGTGVIQNRVGTELSYREIIEYMIDDSDNTGANIMIDKLGGF +QLINNKIKSMGATDTKLRRKMLDTK-ALDNGRDNTTSARDMGTTLKMIYNHHLVSREADD +EMLAILRKNQN-RTKLPNQLPSTATVYNKTGEYDYGVQNDAEIVRNSQGA-FVAVVLSED +GEET--DQLAAMNKLGLM----- +>[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) TaxID=358681 RepID=C0ZJI1_BREBN +--ELEKRLSAIIGQAEGTWGVVVEEQGSAKRF-EHVPDELFIAESVIKVPIMAAVFAASE +QGHFRLDDQLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK +DQIDQTMIDLGMHQSCYSRKLMIYPLD--ITENNKITAGDVASMLGHLATGSFLSQRACK +EMIAIMKKQQV-RNGLPSQLPHGWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD +VT--AQSALNTLGLLGRAVYDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter sp. 94 TaxID=2183922 RepID=A0A495SZU6_9SPHI +-qKLTAQLQAATKGFNGDIGIYVQNLKTGKTA-QINADTLFPTASMIKVSILSGLMDKIQ +KSELQYNQKLVYRDSLLYAGEDILGSFKDKDIQLSKVAMLMITMSDNTASLWLQKLV-GA +ENINNWLDANGFKAMRVNSRIPARRPIWEKYGWGVTTPREMCRLFTMIRDGKAVSPAASE +RMSRTLNRIFW-DETALSQIPPYVQTMSKQGAVD-ASRSETVLVNAPHGD-YVFAVITKN +NKTKDNEADVLIKKVSALVWHYy +>[subseq from] Beta-lactamase class A n=2 Tax=Lactobacillus senmaizukei TaxID=431273 RepID=A0A0R2DEA2_9LACO +---------QTVGKLKGHNSVAIATSFSGDHY-QWHNQ-AQRAASDIKVFILATVYHQVD +QGKYQLSGHYTLRDADKVGGTGSLQGMAAGTVTNQQLLHYMMTVSDNTATNVILRQVGGL +GVVNQYARELGAKDTHVVRKMMDQK-ALDAGTDNLTSVADLSMVLMKLWRHQLISTSADT +AMLKLMSENTN-HSKLPKNVPTDRTIYNKTGEFDYGVENDAAIFAK-GGKAVVVVAMSEG +GQQQIPAMNRL------------ +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus pyridinivorans AK37 TaxID=1114960 RepID=H0JPM0_9NOCA +----------------------------AATL-SVRGDERVVLASVYKLPLFLAFCAEVD +AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT +TTVEKLLARLGLTRTRIIGGTADVYQAYDPAYTSATIPEEMTRLLEAVWSGSVLSPESTA +FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Compostimonas suwonensis TaxID=1048394 RepID=A0A2M9BU93_9MICO +----TAQLDALVAEAGVRMGVSVTDLSGDASV-TVGSEEQYKAASLIKLPLLGLLMDDAD +HGTLSLDESITIPADNIVGGSGTLRDRAFPLITVRELMELMVQISDNTATNVLIDRAGGF +DAVNEYIAALGYEQMWLGRKMI--HPALPPLQENWLNSEEVTDLLTKFYKHEILSPASSE +HIIDLMKGQLV-DTKFGAVIPRE-VLANKTGELGD-VTHDSGIILVPGREVALAATTAFD +PSRPRTEVDLYVQRAATIVYE-- +>[subseq from] Serine hydrolase n=1 Tax=Salegentibacter salinarum TaxID=447422 RepID=A0A2N0TU74_9FLAO +-tKLEQKLKELTESFKGDVGVYVKHLKTGKEA-TINADTIFPTASIVKVPILLKIFDKIE +NGELSYKDSLVYSEDRIYGGSGLMQFYKDSTTDLRTLVALMISYSDNVTSLWNQELAGGG +KAINELMAEIGLEHTRVNSRTVGRDKDWEKYGWGQTTPREMASILEKIRNRELVSAAASG +EMYRLLGNSFY-QDYALSQVPPYVQAAAKQGMVNK-SRSELFMVNAPSGD-YVCYIATKN +NEDDNNEAWQLQKEISALLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus antibioticus TaxID=2570228 RepID=A0A4U2Y0Y2_9BACL +--ELEKRLSAIIGQAEGTWGVVVEEQGKGIRF-EHVPDELFIAESVIKVPIMAAVFAARE +QGHFRLDDQLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNVLIDLV-GK +AQIDQTMCDLGMRQSYYSRKLMIYPLD--ITENNKITARDVANMLGQMATGSYLSERACK +EMLAIMKKQQV-RNGLPSQLPNEWELPCKSGWDT-GRQHDVGLLYTKNR-CFSITALSKD +VT--AQSALNTLGLLGRAVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Hungateiclostridium thermocellum (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) TaxID=203119 RepID=A3DEM2_HUNT2 +-aALENKLRKYISKYNCYFGIYFVDLESGKEF-GINDTEEFFAASTFKIPLNLYVYDMIR +KGMLDPMTSLEYTEEDFEGGTGIIWNSFGKTFTIKELLRLSIVYSDNVAVNMLLRCV-GK +ANVKEYMRRLGGVVV--------------DDGKNVSCPRDMAMYLKEVYELSENGDPWGR +ELVQNMINTKF-YDRLPVLLPKNLKIAHKTGNYT-GVVHDVGIVYAE--KPYIVVVMTKN +VK-NGQSANKAIANISKMIYDY- +>[subseq from] Serine hydrolase n=1 Tax=Planomonospora sphaerica TaxID=161355 RepID=A0A171BK04_9ACTN +-------------------FLHAVDLDTGAEI-AHGADQAVVTASVFKVALLVEFFRQAD +RGALDPAERVRIVADGHTPPTGVSAMTDDVTISLRDLAYLMIAVSDNTAADTLIGRV-GL +AAVNTMLASFGLAGTWLEHDCAGLFAVLDPARTNRSTPRETTRLLGMIWRDEAASPESCA +WMRRLLGLQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEAGVVEYPDGGRYAVAVFTRS +TAQNQPRADAVIGTAARIAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus horneckiae TaxID=549687 RepID=A0A2N0ZJM9_9BACI +-kQLESEIKELAANLDGRASIYIESA--AGVI-DVDGHHSFSSASLIKVPILMAAFHQCE +QNQLKMEEKLLVSTDRKVGGAGVLQALSNKLMKLIDLLTLMIIVSDNTATNILIERL-GM +ENINKYIHSLGMRNTLLQRKMMDTV-ALENGIDNKTTAADMVYALKSIKAKQLFSAENSN +KMLEILSQQQF--LKLADGIDEYFTVASKTGELA-GVQHDCAIISSQQT-VLYAAVLIDE +LTLP-ETGKKTLL---------- +>[subseq from] Serine hydrolase n=2 Tax=Chroococcidiopsis TaxID=54298 RepID=A0A433UQ26_9CYAN +------DFQPLVSNFQGTTGIIIKTLDSGSCF-QFNPNLVFPAASLIELPILWEFFHQCA +TGSLDLAEEIELQSEDMVIGFGILRQLKPGLLCLYDLAVLMTVVSDNTATNLLIDKL-GI +DNINDSIQRIGLTHTILQYKMYDSIS---TSQDNLTTPSDMLRMLEAFIQDKHLLSKYGD +EPLKILEGQQC-KNKLHLGIPKGARLANKTGETL-GTEHDIGVLLGREE-TVIIVVMTTG +LSEN-YQGIELCRDVARLVYQ-- +>[subseq from] Beta-lactamase n=1 Tax=Stigmatella aurantiaca (strain DW4/3-1) TaxID=378806 RepID=Q08XP3_STIAD +----NRLVEEAVRGFDGELSLYVLDVTSGEEY-AYDAERPTYLSSAIKLGVMLEVMHQVD +QRQLSWEETLTFTPEAIRDMHRLHRAQPGDTLSVSTLLEAMMVDSDNAAADLLIQRV-GV +DNVQAQLAARGVRTGPVSSLLEERRRAFYADNVNSASMRDMGHLLQQVARCEGLSAASCT +RAHALMRACQTGSARVAAGLPEAAAWAHKTGTQHR-RACDLGFLSLPSGHTAVIAACTRN +FW-HVSDAERLFAFLGESL---- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus sp. FeSDHB5-19 TaxID=2528713 RepID=UPI0010754CC2 +------------RGFAGEVGLLVASLDGEVLY-RHAEDRGFPAASTIKVPLLIAALQRAQ +AGDLDLDGRVMMQDTDRVPGAGVLHELAGGLLTWRDVLTLMIVVSDNTATNLIIERL-GL +DPFNAWLRARGLRETRLVGKLHLRTEAQQRGERNVTSARDQAALLLGLVRGEVLDGEHTL +LALEILKRQQL-RDIIGRRVPRDYAVASKSGELS-GVHHDVGVLYTP--RPLVVALLSQG +GHDPRE----------------- +>[subseq from] Serine hydrolase n=1 Tax=Halomonas sp. PYC7W TaxID=2282305 RepID=A0A368TRQ0_9GAMM +------------------------------------------------------------ +------------------------------------------------------------ +-----LARRLGDARDALQTSLDDAFRAYYGTDLNAGRLDTFAELLAALGEGRALGDEATA +ELMAILSRTSSGKRRLKAGLGRDIRFAHKTGTQHR-RACDAGIATHGEGRQRVVVVACAR +GVLNVARSEQILAAVGRALYE-- +>[subseq from] Putative beta-lactamase n=1 Tax=Gemmatirosa kalamazoonesis TaxID=861299 RepID=W0RMR3_9BACT +--RLHRTLDSLAESHRGILGYTVWNLDTGERL-ERRGDETFPTASLIKVSILVTVFDLVE +KKMLSLDDPLTVLKIDQVPGSGTLQFHPGIEISVRDAAWLMTTISDNTATNLLLDRI-VI +RRTWDKMESLGLMHTKVHSKSFIRAASVAMDSSGVTTPNEMAKLFALLADGKAVSPAADS +TMLDFLAHNQDET-KLVRWV-DGVRVAHKTGDVDQ-SRADCALFYLQSR--VVVCGLTKE +NVAIDAEGNAVLARLGKAVADAw +>[subseq from] Serine hydrolase n=1 Tax=Luteimonas aestuarii TaxID=453837 RepID=A0A4R5TQS0_9GAMM +------------------------------------------------------------ +----------------------------------------------------------GE +PRLQALARALGVERSELRTSLKAAFDDYYDSGTNAATLPAFARMLERVAAGELLSPESND +ILLSHMRAITTGGRRISAGLPAGTDFAQKTGTQLE-RACNVGILDAGKGEGATVVVACAE +DFGELAQAEQAFQSLGQAL---- +>[subseq from] Class A beta-lactamase n=1 Tax=Brevibacillus fortis TaxID=2126352 RepID=A0A2P7ULI3_9BACL +--ELEKRLSAIIRQAEGIWGVVVEEQGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE +HGQFRLDDQLALRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK +AQVDQTMIDLGMKRSYYSRKLMIYPLD--ITENNRITAGDVASMLGKMATGSYLSQRACK +EMIGIMKKQQV-RNGLPSQLPSQWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD +VTA--QSALNTLGLLGRAVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora spinosa TaxID=60894 RepID=A0A2N3Y447_SACSN +------------DGLPGRAGFAAWDLDEQEPV-LVDAEQVVHAASTIKVLIMIAALRAVQ +EGRIGLDEYVELPAE-RVGGFGILRELLSVTISLRDVITLMIVISDNAATNAVIDAV-GF +EAIRDCAADLGCTATRVERRLMDPNAH----GRNETTALDQARVLDALARGAALPPDLTE +HALEVLSKQQV-RDRLPALLPDGAQCWNKTGELL-GLRHDVGLIGAD-RPQAVVAVLVDE +LTDER------------------ +>[subseq from] serine hydrolase n=1 Tax=Streptomyces ochraceiscleroticus TaxID=47761 RepID=UPI0004C77F65 +----ERTIREMFADAGVRGWLHVAELDRSARV-TLDPDEAVPMGSVYKVPLMVAFCRLAD +AGELDPRARLTLEPPDRVAPTGISILRDAVTMSLRDLVVMMMSVSDNTAADALLRTI-GT +SVVDEVCRDLGMPDTRIHGGVAGTWDVYNPLSKAATTPADMARLLRAIWTGRAASPERCA +FMREVMGRQPW-RHRLASGFPDDVTVSGKTGTFG-AMRHEAGVVELADGSTYTAVVFTQA +ARADLPRADAVIGAAARTAVE-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus pyridinivorans TaxID=103816 RepID=UPI00110D9FF1 +----------------------------AATL-SVRGDERVVLASVYKLPLFLAFCAEVD +AGRLDASGQLRIVPSDWTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT +TTVEKLLARLGLTRTRIIGGTADVYQAYDPAYTSATIPEEMTRLLEAVWSGSVLSPESTA +FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Lentzea guizhouensis TaxID=1586287 RepID=UPI0009F23DF5 +--------------TEGFVHAREIGVQDGPEV-GVGADDPVVLASVFKIPVAVAFAAEVA +AGRLDDTQRTRVTSRYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDVIFHRV-GQ +AAVDAVLANLGLHRTRIMGCCEDLFAIVDPERTTSSTPREITTLLDAIWTGRAAAPQACE +RVRSIMAQQVW-PHRLSSGFPADVQVAAKTGTLP-GVRNEAGVVTYPDGRGYAVAVFTRA +ESLRQPAVDAVIGRAGRLAVDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea wenchangensis TaxID=568860 RepID=A0A1I0LB53_9ACTN +-------FEALFRVAGVTGWLHAADVDTGREI-GHGADEPLPVASMFKVPLLVELCRQAD +AGLLDPAERVTVPAGDRSSPTGVSAMLDDVTMSLRDLAYLMIAVSDNASADELLRRV-GR +EAVNATLEAYGLSVTRVRRSSREIDRAFDPSWGNAGSPRELTRLFGLIWRDEIASAASCA +WMRGVLNAQVW-PHRLASGFPDDVAVSGKTGTLPT-LRTESGVVEYPDGGRYAVAVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] serine hydrolase n=1 Tax=Saccharopolyspora spinosa TaxID=60894 RepID=UPI000C6F3147 +-------------GLPGRAGFAAWDLDEQEPV-LVDAEQVVHAASTIKVLIMIAALRAVQ +EGRIGLDEYVELPAE-RVGGFGILRELLSVTISLRDVITLMIVISDNAATNAVIDAV-GF +EAIRDCAADLGCTATRVERRLMDPNAH----GRNETTALDQARVLDALARGAALPPDLTE +HALEVLSKQQV-RDRLPALLPDGAQCWNKTGELL-GLRHDVGLIGAD-RPQAVVAVLVDE +LTDER------------------ +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=A0A2R3SDP2_RHOHA +----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD +AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSTDQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. K4S16 TaxID=1316147 RepID=UPI0011ED1A9E +--EAAERIETAFRSAGVTGFLHVVDMDTGREV-AVGADEPVVLASVFKVPLLVAFHRQAA +DGVLDPTEQVVLRPDDRTAPTGVSALLDEVRMSLRDLTCLMITVSDNAAADAVMERV-GL +DAVNATAADLGLRRTVILGNGRELHEALDPLRTSRSTPRDMTRLLSMIWRDEAAPPAGSA +AMRRLLGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGARYAVAVFTRS +TLAVLPEADAVIGTAARIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. ADI92-24 TaxID=1522756 RepID=UPI000F54E840 +------------------LHVAELHRPSAQVV--IDPDEQLPLGSVYKVPLMVAFCRLAD +AGRIDPCRRLTLEAADRVAPTGVSVLHDPVTMSLRDLVTLMMTISDNTAAAAVLRAV-GP +DVVDAVCRDLGMPDTRIHGGVVSTFSVYDPAFKASSTPADMARLLRAIWTGEAASDDRCA +FMRDVMRRQPW-THRLASGFPDDVTVYGKTGTFGS-LRHEAGVVELADGSTYTAVVFTQA +ARADLPRADAVIGAAARVAVE-- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus sp. KR-1 TaxID=2662757 RepID=UPI0012D2D687 +------------AGFAGVVGLRVTDLAGTELA-AWNAGRVFPAASTIKVPLLVLALREAQ +AGRLDLSGRVVMQLDDRVPGAGVLHELDGGLLTWRDVLTLMIIVSDNTATNLVIGRL-GV +GAVNAWLAAGGLTGTRLVGKLEQRNEAQRCGERNATTARDQTALLRALVAGQLLDEAHTA +LALDILGRQQY-RDLIARHVPCGYRSATKSGELH-GVHHDVGVLFTP--RPLLVALLSEG +GTDPREPENA------------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium 44-61 TaxID=1895838 RepID=A0A1Q3THH5_9SPHI +-kKLEAELRKAITGFNGAIGIYVKNIKTGETV-AINADTVFPTASIVKVPIMMGVMDKMQ +KGELHYDSTHIYKDSLLYEGEDILGSFKDGEIALKKIIMLMLTTSDNTASLWLQKLAGTG +TRINALMDSLGYINTRVNSRTPGREEIRKIYGWGQTSPAEMGRLFEQIYQNKLFTPAACE +RIMRCLGRNFWDEDEAISMTPPYIEVFSKNGCVD-ASRNEALLVNAPNR-PYIFCIFTKN +NKTHANEAWTLTRKISSLLWDYf +>[subseq from] Uncharacterized protein n=1 Tax=Rhodococcus hoagii ATCC 33707 TaxID=525370 RepID=E9SYY6_RHOHA +----------------------------GVDV-GVGADDPVVTASVYKLPLFVAFCRLVD +AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CS159 TaxID=1982762 RepID=A0A209CB89_9ACTN +--ATAARLDAAFADAGVTGWLHAVDVDSGAQV-GVRADQPVCTASVHKLCVLVTLHELAA +AGALDLTEQVECPPDGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL +DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEAAPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. ACPA4 TaxID=2028571 RepID=A0A2A3FBB4_9NOCA +--SAQQEIAAVLAEAKTDAFVHVRDIDSGQEF-GYGADDGVILASVFKIPVVLEYARAVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFIYNRL-GL +DNIVSTLRSLGLEKTNLVRDCRGLFKVMDPSRTNSSTPREITQLLAAIWRDEAGPASACD +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVTYPDGKRYAVGVFTKS +HEKRAPKIDASIGTVGRIAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodothermus marinus (strain ATCC 43812 / DSM 4252 / R-10) TaxID=518766 RepID=D0MKL8_RHOM4 +-------FGRIEHRYELTLGVAAHNLTTGASV-FYRADTLFPTASVIKLAVLVELYRQYE +QGYLSPQDTVVLTAGRIYPGSGVLQHLSVPRLSLQDAAVLMIILSDNTATNLVFDRL-GP +DSVNATLRSLGLQRTRMLNKPFGFSTNTPEARRGMGTPRELMQLMIAMARGRVVSAEASR +EMIEILKRQQW-TEMAPRLLPDSLQLAHKTGAIST-ARCDVGLIFSPRD-TIAFAVMTDH +IKDPDQVGNLAVAEAVREVYE-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A2W4S431_9FIRM +---LAQVLSAYLSTLRGTYGVAIVDLTTGATA-SVGGDRVFVAASTFKVPLAMYIFSLVE +RGEADLAEPLYYVPADWEGGTGILHGAVPGDYTVAELVNLSLTVSDNIATNMLLRRF-GE +QNVFAYMRELGGTVTNLPTG----RR--------ATTPRDMARYMEIAYRRAAREDGGYR +TLLGLLTQTAF-RDRIAAGAPAGVPVAHKIGTLP-AMVHDVGIVFLPGR-PFAIALFSEG +VS--EPVAAARLADITRLVSDY- +>[subseq from] Beta-lactamase n=2 Tax=Rhodococcus TaxID=1827 RepID=A0A0B1RBA7_9NOCA +----------------------------AATL-SVRGDERVVLASVYKLPLFLAFCAEVD +AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT +TTVEELLARLGLTRTRIIGGTADVYQAYDPAYTSATIPEEMTRLLEAVWSGSVLSPESTA +FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Carnobacterium maltaromaticum TaxID=2751 RepID=UPI0011458BD6 +------------------------------------------------------------ +---------------------------------------------------MLFDQLGGP +AGFQKELEKLGDHTTESVRYEPELNEAIPGDCRDTSTPKAIALDLKKLTADKTLAPDKLT +FYKKQLVENKTGGNLIRAGIPTDILVGDKSGAASYGTRNDIAVLYPPDRKPIVLVIFSNK +TNKDDAYQDELIAKSAKLVGDYf +>[subseq from] Beta-lactamase n=1 Tax=Prevotella copri CAG:164 TaxID=1263102 RepID=R6CNL5_9BACT +------------------------------------------MMSVFKVHQALALCNDFD +KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT +AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD +FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGVNEAQNDVAYICLPNKVCYTLAVFVKD +FKGNEPQASQFVAHISAVVYS-- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Rhodococcus sp. Br-6 TaxID=1522141 RepID=A0A2I9DW06_9NOCA +----------------------------GVDV-GVGADDPVVTASVYKLPLFVAFCRLVD +AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI0009C006FA +----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD +AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSTDQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI000A0F985B +----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD +AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSTDQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2D5NFU9_9BACT +--ALRERLSARLAQFDGDVGVYVRHFEHDQTV-EIAADELFPTASMIKVPILAALLHRVD +SGELDYHEKLTYTSDRLYAGEDLLGSFASGEVTIDKLAFLMITTSDNTAALWCQELAGTG +TAVNAWLEQQGFLRTRVNSRTPGREAARARYGWGQTTPREMCELLARVRGRRLGSAAASE +EMARALGRIYW-DGEALASLPPDVATMSKQGAVN-ASRSEVVLVHAPHGD-YAFCCITNR +QTQSDNQGFVLLRDVSRIIWEHf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. TSRI0281 TaxID=1718998 RepID=UPI0009A11B4D +hpQARDRIRAAFAEAGVTGWLHAVDIDSGAQI-DAGADRPVVTASVHKLCLLVALHQQAE +AGRLVLTEQTECPRDGRTAPTGLAAMLDAARVSLRDAAYLMVAVSDNTAADLLLERV-GL +DAVNDTTRRLGLTRTHATQTFREFLAAVDPARTNRSTPRDMTRLLGAIWRDEACTPEHGA +AIRRLLGLQVW-PHRLASGFPDDVLVAGKTGSAPT-VRNEVGVVEYPDGGRYAVAVFTRA +ASATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus oceanisediminis TaxID=665099 RepID=UPI00119D4348 +---------------------------EDRII-EFNSTEVFRSASLIKLPILFEALRQLE +EGILQPDRLLSVRQEDKVGDTGVLQAMNTQQITIHDLLTLMIIVSDNSATNLVIDLI-GM +APINSTISKIGMKNTILKRRMLDFKAA-QAGNDNFTTSADIVLCLKEAIEGQWLKEQSRD +RFTALLLQQQF-KEKLPAYMDQSMEIGNKTGELA-GIEHDCAFITYGDKR-AYAAVLIDG +LE-DNETGKSIIRQVGKQI---- +>[subseq from] Beta-lactamase class A n=1 Tax=Lentibacillus halodurans TaxID=237679 RepID=A0A1I0XHB0_9BACI +---LEEEVLSIVEEVSEEGDVSIFIDTSEGEI-GVNETEVYSAASTIKVPILVEAIRQAE +QGNLNLDEKIEIDSSDIVGGGGILNDLSENQMTLRDLLTLMIIVSDNSATNMVIDRI-GM +DSVNETCMEMGCEQTKLQRYMMDFSSP----VDNLTNAKDMARILKAIDEANIVSQEGRN +EILRIMREQKL-T----AGLPTEVTFASKGGSLSPQIRHDVAHVTDGNET-AYVAVLTSG +LS--KPTARKAMNKIGEKMAD-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI0007CD66D9 +----------------------------GVDI-GVGADDPVVTASVYKLPLFVAFCRLVD +AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces aureoverticillatus TaxID=66871 RepID=UPI0013D95E63 +--NTATRLQEAFAEAGVTGRLHALDIDSGAEL-GAGADQPVVTASVHKLCVLVTLHEQAA +AGLLDLTEQVECPVDGRTSGPTGLAAMLDPVLSLRDAAYLMMAVSDNTAAELLLERV-GL +DAVNATTARLGLTRTRAVHTFREMFAALDPARTNHSTPRDMTRLLGALWRDEACTPEHGA +AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA +ARATLPSADAVIGTAARMAVE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces coelicoflavus TaxID=285562 RepID=UPI000D599FFC +--ATAARLDAAFADAGVTGWLHAVDVDSGTQV-GVRADQPVCTASVHKLCVLVTLHELAA +AGALDLTEQVECPPDGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL +DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEAAPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Rhodococcus sp. (strain AD45) TaxID=103808 RepID=A0A0D8HW74_RHOSX +--SAQQEIAAVLAEAKTDAFVHVRDIDSGEEF-GYGADDGVILASVFKIPVVLEYARAVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFIYNRL-GL +DNIVSTLRSLGLEKTNLVRDCRGLFKVMDPSRTNSSTPREITQLLAAIWRDEAGPASACD +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVTYPDGKRYAVGVFTKS +HEKRAPKIDASIGTVGRIAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=bacterium (Candidatus Blackallbacteria) CG17_big_fil_post_rev_8_21_14_2_50_48_46 TaxID=2014261 RepID=A0A2M7G9A5_9BACT +------CLRAHLEKLEGQAGFCAENLHTGQKI--CHGDRRFLSASTIKIPVLALYWADRE +KGHF-AETEYLYQSQDWVEDSPYFENIAPGSIPWDEIARQMIIISDNTATNLLIQRL-GL +KRIQAWLNANGFKTTRIERYMMDLEAR-AQGIDNWTSPSEMCRLMKKLVKGEVTEPGSQQ +AILQTLHQQQD-LEKIPHFFSAPILVANKPGELP-GTRSDVGYLHNAQH-EIVMALFTDQ +LK-NEATSDLWLATLAQILWR-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia fluminea TaxID=134984 RepID=UPI000C70F9D4 +--------------------LHARRCDSAGEV-SVGGNDRVVIASVYKLLLLAAFLRQVD +HGLIDPAGRLTIDPSDCTPPTGLAALHDPVTLSRRDLAMSMMTVSDNAAADVLLGEV-GL +AAVGELVHELDLPDTRIIGGTADQHRAYDPSYASATTPEEMTRFLWKLWSGDILSTASTE +FARTVMSKQVW-PHRIAAGFPRGVLVAGKTGTIGV-IRNEVAVIEFPGETPVAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Rufibacter sp. NBS58-1 TaxID=2595005 RepID=A0A5B6TTW6_9BACT +-kQLTQKLQTLTKDFQGEVGIYVRHLKTGKTV-AINADTLFPTASIIKVPIMVAMFDKIE +RNEIDPKTILRYRDSLYYAGEDIVGSFKDSSVALSKIQMLSITTSDNTASLWLQQLAGTG +TAINAWLEKNGFTYTRMNSRTPGRRPNWEKYGWGQTTPREMATLVTMIREGKAVSPAASE +RMYRNLGRIYF-DSEALSQIPPFVHTASKSGAVNR-SRSEVVLVNAPHGD-YVFCIITKN +QKDESNAGYALIRAVSKTLWQHf +>[subseq from] Serine hydrolase n=1 Tax=Lactobacillus pentosus TaxID=1589 RepID=A0A2S9VYZ9_LACPE +--QIRNDISSTVGAISGTNSVYVSPVNSKQTV--LVNDGSQRSASSIKIFIMVTAYAMAK +EGVFNLTDTHTVTDSEKVGGTGVIQNMDAGTLSYQEIIEHMIDDSDNTAANIMIEKLGGF +DLINNKISNMGATDTKLRRKMMDTK-ALDDGKDNTTSAHDMGMTLKKIYNHQLVSRQADE +AMLTILAKNQN-RTKLPKDLPSSATVYNKTGEYDYGVQNDAEIVKNSHGA-FVAVVLSED +GDQ--NDQIDAMNRLGSLLYQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5QD35_9BACT +-eTLQQNCQRIMSESKAAYAVALLDYEDGFRF-TIDADRPFHAASTIKVAILLAVAKAFD +EGRIRPDDTLHIRNRFLSARTPFRHRMVGRTAKISDLAEWMIVSSSNLATNLLLDYV-TI +EYALRVLRDAEVSGINLRRGVDDTKA-HANNFNNETTGEGLLKLFSTL-RGDFLSKTGRD +FVINILLQQRF-NSMIPAPLPPHASVAHKTGEIST-ACHDAGIVYLPEREPYILVVLTEV +MAES-NGRRESIAKISEAVF--- +>[subseq from] serine hydrolase n=1 Tax=Nocardia salmonicida TaxID=53431 RepID=UPI0007A371BB +---------------------------SAGEV-SVGGHDRVVVASVYKLLLLAAFLRQVD +HGLIDPAGRLTIDPADCTPGPTGLAALLDPVLSRRDLATSMMTVSDNAAADVLLGEV-GL +AAVGELLQELGLTDTRIVGGTADQHLAYDPSYASATTPEEMTRFLWKLWSGDIVSTASTE +FARTVMSKQIW-PHRIAAGFPRGVLVAGKTGTIGV-IRNEVAVIEFPGETPVAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI000A11CEDB +----------------------------GVDV-GVGADDAVVTASVYKLPLVVAFCRLVD +AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces pristinaespiralis TaxID=38300 RepID=UPI0005692356 +---IEERLRAVFAGAGAEGVLHAVDIDGPGEA-GYGADEPVVVASVFKVLLVLEFARQSA +AGQLDPRERVRVTSEHRLGGWGTGGCLDDVELSLRDLAHFAMAVSDNTAADLLMERV-GT +DTVAMLAKELGLENTRIVGGPRQVLEVYDPARTNASTPREMTRLLRMVWRDEAGPPEACA +QVRELMGRQVF-RHRLAAGFGDGVRVAAKTGTLP-GLHNEVGVAEYPDGGRYAVAVFART +PGANRTETDVAIGAAARTAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. AJ005 TaxID=2652443 RepID=A0A5J6YSX9_9DEIO +------------QGYVGEVGLRVCDLLGRELF-ALNPERVFPAASTIKVPLLILALHWAQ +AGRLDLESRVTLEAIDRVSGAGVLHELEPGLLSWRDVLTLMIIVSDNTATNLVIGRL-GV +DAVNDWLTTHGWTETRLVGKLEERNAAQLRGERNRTTAADQTDLLGRLVRGELLDTAHTA +HALNILERQQF-RDLIGRGLPRAYSLASKSGELD-GVHHDVGVLYTP--RPLVIALLTQG +GTD-------------------- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus sp. SDU3-2 TaxID=2651870 RepID=UPI00128BFAFB +-------------GYVGEVGLLVTDLAETELF-ALNPDRSFPAASTVKVPLLVQALEEAQ +AGRLDLSARVTMTAQDRVPGSGVLHELGAGLLTWQDVLTLMTVVSDNTATNLVIGRL-GE +GAVNAWLALRGLTHTHLIGKLERQNEAQRRGERNRTSAQDQVALLGRLVRGELLDPPHTE +LALSILTRQQF-RDILGRHVPRDYRVASKSGELR-GVHHDVGVLFTP--RPLVVALLSQG +GL--------------------- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI0009BCDD9F +----------------------------GVDI-GVGADDPVVTASVYKLPLVVAFCRLVD +AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV +DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTMLLSAVWSGAVLSADQTA +FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGQAARTAIA-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. NEAU-LD23 TaxID=2486417 RepID=A0A3M8VR32_9ACTN +---ARRTIRGLFADAGVRGWLHVADLHRPEACvAIDPDEPVPVGSVYKVPLMVAFWRLVD +AGTLDPCERMTLGPSDRMPPTGISILRDDITVSLRDLVTLMMSVSDNTAADVLLRRV-GT +EAVDEVCRDLGMPDTRIHGGVATTFAVYGPLLKSSATPADMARLLRAIWTGRAASADACA +FMREVMGRQPW-THRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELADGSAYTAVVFTQA +ARADLPRADAVIGAAARTAVE-- +>[subseq from] serine hydrolase n=1 Tax=Desulfofarcimen intricatum TaxID=1285191 RepID=UPI0008348453 +-hELKNKLEQMLKQEQGTYGVFVIDLKSGRAL-GVNPLEPFHAASTFKLPLNVYLYKKIA +QGEVDPQNMLVYESSHYEGGTGQLQKPVGSSFDIETLSKYSIVYSDNVATNMLLTYL-GK +QNVKNYMRAAGGLVV--------------EDNKNITCPRDMALYMKELLDFNAEQPAVTS +KLIDHLENTVY-NDRISKLLPDNIKVAHKVGNWPTGTYNDVGYVQHPEN-PYIIAVFSKN +TP-GINSAFGVIQRVSKTVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Aphanothece cf. minutissima CCALA 015 TaxID=2107695 RepID=A0A2T1F091_9CHRO +----SQQWARLAAQKGLTASAFLLVLDDGRYA-ELQPDLPLSAASSIKVPILLAGLEDLD +RGKLRWNEPMPLTKEVVGGGAGWMAKPLGTRFPFFEAATEMIRVSDNTATNLLIRRLGGK +TELNSRFRSLGLTATVVNNWLPDLDGT------NTTSSRDLARSIALVDTGDKLTPRARD +LFREIMGTSRT-NTLIPELLPEGITVYNKTGDIGI-AYSDTALIQMPNGQRAVLAVMVKG +PFND-PRSAELIRSMAGAVTK-- +>[subseq from] Secreted beta-lactamase n=2 Tax=Streptomyces pristinaespiralis TaxID=38300 RepID=B5HHK2_STRE2 +----EERLRAVFAGAGAEGVLHAVDIDGPGEA-GYGADEPVVVASVFKVLLVLEFARQSA +AGQLDPRERVRVTSEHRLGGWGTGGCLDDVELSLRDLAHFAMAVSDNTAADLLMERV-GT +DTVAMLAKELGLENTRIVGGPRQVLEVYDPARTNASTPREMTRLLRMVWRDEAGPPEACA +QVRELMGRQVF-RHRLAAGFGDGVRVAAKTGTLP-GLHNEVGVAEYPDGGRYAVAVFART +PGANRTETDVAIGAAARTAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E1KRX3_9PLAN +-----TQLDSLAKSFAGRLGFYAKDVRGGATY-AFNDDQRFPPASVIKLPVMIQLYRQAA +LGHLQLEEKHRLPIDISTHGTGVLKARDGLILPLREYGRLMMIHSDNMATDLVIRTV-GT +KSTNQFLDDQGCQSTRVSLELGRWHYYSDSLENNVCGPRDTGLLLERLYLGQLANRSDTD +EMLNLMRASTH-KQTIARYLKPGVRVANKYGGSRR-IAADVGIVELPER-PVVIAAFAIS +NAADDRSGRGILARMSRLVIA-- +>[subseq from] Serine hydrolase n=1 Tax=Panacibacter ginsenosidivorans TaxID=1813871 RepID=A0A5B8V9E4_9BACT +-tKLQSQIKFLLQGFHGNVGVFVHDLKHNKIV-ALNADSVFPTASIVKMPILLGIMDKIT +TGQLNYHQRLTYTDSLFYDGDDILSSFKDSAIELSKVMMLMLTISDNCASLWLQGLSGGG +KRINELLDSLGFKNTRVNSRTPGREADRSQYGWGQTTPREIAGFMERVVNNQLLDKASDE +KMLRLLGRQYW-DEEALSQIPPGVFVADKNGAVDE-SRNEVVYVNSNNN-PYIFSIFSKN +NADTNNEAWVLTRKLSSLLWQYy +>[subseq from] DZANK-type domain-containing protein n=1 Tax=Lactobacillus pentosus TaxID=1589 RepID=A0A2S9VJN1_LACPE +--QIRNDISSTVGAISGTNSVYVSPVNSKQTV--LVNDGSQRSASSIKIFIMVTAYAMAK +EGVFNLTDTHTVTDSEKVGGTGVIQNMDAGTLSYQEIIEHMIDDSDNTAANIMIEKLGGF +DLINNKISNMGATDTKLRRKMMDTK-ALDDGKDNTTSAHDMGMTLKKIYNHQLVSRQADE +EMLTILAKNQN-RTKLPKDLPSSATVYNKTGEYDYGVQNDAEIVKNSHGA-FVAVVLSED +GDQ--NDQIDAMNRLGSLLYQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonas phototrophica TaxID=1379270 RepID=A0A143BLN5_9BACT +--TLRRTIDSIADGHRGVVGYSITNLETNEHL-ERRGDEPFSTASLIKVPILVALFDLAE +QQQLSLEDPVVLTAIDKVGGAGQLQYLRTPLLRLWDAAWLMTTLSDNTATNLVLDRI-KI +RRVWQKMEALGLPRTKVHSGSMTRIASSAKYGLGVTTPNEMAQLFTLLAHGKAVSPRADS +VMLDILEHNEDDSKLMR--FNYGVRAAHKTGDVDQ-SRTDCGVLYLPAR--VVACVLTRE +NVDKDSEGNAVIARIGQAVAAHw +>[subseq from] Serine hydrolase n=1 Tax=Subdoligranulum sp. AM16-9 TaxID=2302960 RepID=A0A372V9K4_9FIRM +-eKLRQQIEQRLSAVMGDACFYYENLATGVCF-GHAADKPVVAASVIKLAVLIEAFRQMD +TDAVRANEMFVIARTDKLPSCGALNYLHDGLVTFRDLCVLMTILSDNTATNLLIKRL-GI +GNINDTLRMLGAEKMTLNRLLFDREA-SSRGIENYITAREAGLLLKRLYDGEAVSGPASE +DMLSILKDQRL-NGKIPFLLPHSVKIAHKTGEDD-GITHDVGIVYA--RQPFIVCFCGEH +V--SPPEFERAMQDITLMLYE-- +>[subseq from] Beta-lactamase n=1 Tax=Ruthenibacterium lactatiformans TaxID=1550024 RepID=A0A0D8J3S6_9FIRM +-eKLRQQIEQRLSAVMGDACFYYENLATGVCF-GHAADKPVVAASVIKLAVLIEAFRQMD +TDAVRANEMFVIARTDKLPSCGALNYLHDGLVTFRDLCVLMTILSDNTATNLLIKRL-GI +GNINDTLRMLGAEKMTLNRLLFDREA-SSRGIENYITAREAGLLLKRLYDGEAVSGPASE +DMLSILKDQRL-NGKIPFLLPHSVKIAHKTGEDD-GITHDVGIVYA--RQPFIVCFCGEH +V--SPPEFERAMQDITLMLYE-- +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. WAC 06369 TaxID=2203193 RepID=A0A429G0S2_9ACTN +-----------FRDAGVTGHCHAVDVDTGRDV-GVRAGEPVVLASVFKVPLLVAFHRRVA +AGTLDPTEPATLPAADRTSPTGVSALLDDVRMSLRDLATLMITVSDNAAADYLLDRV-GL +AAVNAAAAELGLPGTHVSGSGREMLDVRPLDPTSRSTPREMTRLLSLIWRDEAAPPAECA +AMRRMFGLQVW-PHRLSSGFPEDVVVSGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRT +PVAVHPAGDAVIGTAARMAVEH- +>[subseq from] serine hydrolase n=1 Tax=Pontibacillus yanchengensis TaxID=462910 RepID=UPI00136D0925 +--RLENEVTEIVSKLDGNASVVIQTI--NGTI-AMNEKEVMPAASVIKIPIMMEAFRQAK +TRGVDLSATVTIPQHNKVGGAGVLQFLSQDAFPLHDLVTMMIIVSDNVASNAVIKHI-GI +GNVNHLIEELGCSNTKLRREFMDLKAQ-EQGLDNTTTAEDMVKLLEQLTLQD-------R +EMVEILKGQQL-TSQLPAHTYEDLEVANKTGELD-GVNHDVGILIDSHQ-TVYVAVLLND +VR-DTVEGQRAIADIGNQVMQY- +>[subseq from] Uncharacterized protein n=1 Tax=Bdellovibrionales bacterium GWB1_55_8 TaxID=1797386 RepID=A0A1F3T2Y2_9PROT +---LDQEVRRLERAYPGKFGLYMKRLSDDRVF-SHRGSARWYIASGVKVPIAVEALVRAS +EGKISLSDRIDLSEDDYVDGAGQTNYHPPGSLSIRYLLQQMLVYSDNTAADLLLRKV-GL +QSVNERVKVLAPEAFGEITELSEVRRAYYRTGVNSATLEGYARILERIAKNEVLDPLHTK +LLLEWMDGVKTGRNRLIAAFPNTVVFAHKTGTQFQ-RICDFGVARKRTRKGVVIAACVQG +LP--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Caulobacter radicis TaxID=2172650 RepID=A0A2T9K9L0_9CAUL +----SLKLTAIAERAPGDLGVAVQDLTTAQRA-TVAGDHLFPLAGIWTAALGAAVLAEVE +AKALSLRETITIEDVDLSPPSGVADAWPSRRWTVEELLKHAVAGGDNTAADVLMKRIGGP +GAVTAWLDLKKVENLRVDRYARQLLPDYLADPHDSTTPLAAVRFLEALNQAELTSQDGRR +RMLRMMEAAA--GERLRPALPAGARLAAITSATPTAADNVLAMVRLKDGRRFALAILLKA +SPLEEADRDALMLEVTRTVLQ-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus horneckiae TaxID=549687 RepID=UPI00082CE5C7 +-----EEVIRRSSLCKGRVGLLIES--ENKRI-EINSKMKFPSASLIKVPILIECFRHSE +RGILDLDQYIPMTASNKVKGAGVLHALSSDILKVIDLMTLMIIVSDNFATNLLIDLV-GM +EKINCGFKELYLKNTELNRKMMDFS-AWKKGVDNYTTASDMITCLKELDQNQFLSKRYAS +MAKDILENQQF-NNKLSDQIDDRFKVANKTGELF-GVEHDCAIIQYEKR-SIYAAVLIDQ +LINP-KDGRQTLSSIGQLISQ-- +>[subseq from] Uncharacterized protein n=2 Tax=Bacillus sp. 349Y TaxID=2653176 RepID=A0A653MGQ3_9BACI +--DLREDLMKVIHECPGSVSFTILS--NDESL-SWEENRRISSASLIKLPILMAAFEQIQ +TGSLNGDAMVVLRHEDHVEGAGVLNGHDGITLSIEDLLTLMITVSDNTATNRLIELI-GK +DSINRLCLAWNLKRTFLNRKMMDFRS-LEMGQDNWTSSMDVVSCLKGINEG-AFEEISRR +KMLTMLSRQQF-RDKLPALVGGDVKVFNKTGELP-GVEHDCAILESTSGKIAYVAVLIDE +LHAP-EDGRKAISRIGKLVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. Ru73 TaxID=2080748 RepID=A0A2S4XQC1_9ACTN +-----RTIREMFADAGVRGWLHVAELHREARV-TVDPDEPVPMGSVYKVPLMVAFCRLAD +AGEIDPRRRVTLEPSHRIAPTGISILQDPVEMSLRDLVVMMMTISDNTAADAVLRAV-GA +TAADAVCRELGLPDTRILGGVAETWAVYDPVSKASTTPADMARLLRAIWTGRAASPERCA +FMRDVMGRQPW-RHRLASGFPDDVTVSGKTGTFG-AMRHEAGVVELADGSAYTAVVFTRA +ARADLPRADAVIGAAARTAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3C1JKH8_9CHLR +------------------ASIAVVHLETGASA-TVNGDRIAVPASLYKVGVLVEAFRQIE +AGLLRLDETLRLLPIDWAPGAGILQGRIGTQVTITDALRLMIGISDNTAAHAIVRRI-GV +DRVNANNQRLGLSNTRY----------YIDDRPDTTTAADMARLLSLLATGRLAGVEATG +QMLDLLQQVQP-AAWLPRGVPPTIAVAHKSGQLD-AVRNDAGIVFGPTGR-YVVVVLTDN +RP-NAMKGENAIVQVARSVHAYf +>[subseq from] serine hydrolase n=1 Tax=Mycolicibacterium porcinum TaxID=39693 RepID=UPI000A996A81 +------------------------------------------------------------ +------------------------------------------------------------ +-GITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAAGYRQVLAGDALSPPQRR +QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS +QADDADNLRPLIGELTAA----- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudonocardia hierapolitana TaxID=1128676 RepID=A0A561T5D6_9PSEU +--ELEREIRRTFADAGVHGRLHAMPLGGDREV-GVDPDEPVVMASVYKLPLLVAFCRRVD +AGELDPREQVTVDPAGRTAPTGLSVMRDPVTMSWRDLACSMIGVSDNAAADVLLRRV-GL +DHVNETLSDLGLERTRVLGGTADVYRAYDAVLASATTPREMTRLLAAVWADRAASPQQCR +FARELLGAQAW-QHRLRSGFPVGVRVAGKTGTLA-AVRNEVGVVQFDGERPVAVAVFTRA +ARAELPRADAVIGQTARLAV--- +>[subseq from] serine hydrolase n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=UPI00040E4062 +---LAQRIEALSNADSTRYSVYAAFPEENSTP-YLYQSEPMRSASMIKVFLLADAMEKVR +DGKLSLDSTITLHASDKVGGAGILCGYANGSLSLDTVLRLMITESDNTATNLVIDLL-GM +DDINAYIQRNGYYDTKLARKMMDFAA-VNAGLDNYTSVQDLGSFFLKLYQHDCVGFEQDE +IMLSYLKGQTD-KECFPAALP-GAVIAHKTGELG-GLYDDGGIIYVDNRT-MILVIMTEH +YSSR-YRAIETMKAMAQAA---- +>[subseq from] Beta-lactamase n=1 Tax=Rufibacter sp. DG31D TaxID=1379910 RepID=A0A0H4VLQ3_9BACT +--KLIQKLQALTQRFEGDVGIYVRHLKTGKTV-ALNADSLFPTASMIKVPIMVGMFDKME +RGEIDPKAILRYRDSLFYAGEDIVGNFKDSSVALSKVQMLSITTSDNTGSLWLQQLAGGG +AAINAWLEKNGFAHTRVNSRTEGRRPNWQKYGWGQTTPREMANLVTMIREGQAVSPAASE +RMYRNLGRIYF-DSEALSQIPPTVNTASKSGAVNR-SRSEVVLVNAPHGD-YVFCIITKN +QKQDNNAGYALIRAVSKTLWQHf +>[subseq from] serine hydrolase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI000BF850CD +-----------TKWKQSNNGLIRIHIEGKESI-RINSFIQQRAASTIKLLLAIEAFRQID +EGILTLTSVIQRTEKNTVGGAGVLGALPRLTIKVEELLTLMIIVSDNTATNELISLA-GF +EKINECARNMGLKKTVLNRYMMD-ETAVKQGLDNYTCASDVVECLREIYEGNLLKKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LSEN-EQGRRLIADIGYL----- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E6WQV9_9CHLR +------DINLIIKDVPAVVGVAARHIHTGKNY-YNKADDIFFTASTLKIPLIFELYRQVD +KGIINPMQRISVN--DKSPGSGVLKDSIGINPTIYDLATLMIIISDNTATDIIYKII-GK +DNLHKTLLDLNLKSTHLPMTCKELLYALSEDKSDVSSPNDMINLMEIIYKKELLTKKSSD +IILDIMYRQQA-KTIIPYFLPSNIKTFHKTGGVTS-VRCDVGIVNGKSG-PYSIAIMAKD +VK-DDKNIDLSLARISEAVYHFf +>[subseq from] Beta-lactamase class A n=1 Tax=Lactobacillus diolivorans DSM 14421 TaxID=1423739 RepID=A0A0R1SAW5_9LACO +------AEKQCIKSSAGKTSVFVDSLNNGQLI--VTNNQVQRSASVIKLFIMIDTFHQIQ +TGRLKLNQLVSFPKSDRVDSTGELANQAVHQVSVSELLKLMIRNSDNSATNVLIDHLGGL +NIVNEEIRRLNCNHTKLQRKMLDYQ-ALQSGKDNLTTSKDIGKILVRLYHHHVLRNPYDS +AMLQLLRHNAN-QSKLPALINQKSVIYNKTGEFQYGVQNDAAIIKKGNQA-FIVVVLSEN +GVQT--KQINAM----------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium 50-39 TaxID=1895841 RepID=A0A1M3H3Z5_9SPHI +-rKLEEKLQALTDTFHGVAGVYVRNLRTGKEV-TINADTVFPTASIIKVPILVGIFDKIQ +QGEFPYHQPLVYRDSMSRKGSGLMQFFRDSTTDLQTAITLMITHSDNAAAVWCERLAGGG +AAINAWLSAHGFEYTRLNARTAGREQARQQYGWGQTTPREMARLVSMIRNDAVVSPAASQ +TMYRIMTHVFW-DEYALYPLPPYVQAASKQGMVDD-SRSEVVLVNAPHGD-YVFYVATKN +NKDQENEAWQLARRVSALLWDYf +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacterium sp. TaxID=1872119 RepID=A0A2G4JGC6_9BACT +-------LARTVAEFPGHAGIWVKHLTTGESA-GIQDTELFNSASVIKLPVLVLAFQMAD +RGELKLDERITITKEDLRGGSGIFRYHDTGLPTLRDVLLQMVITSDNTATDLSIAKVGGV +AKVNAWLRDKGYAGMRLVQTTGELFTSDRAYWLGEISARATGQMLEAIEKKTMASPASCD +AMLRMLRAQQAGQRRLNHYLS--VPVAHKTGDFPPVLANDVGIIYARSG-PLVVSFLGNA +ITGNYGEAEDRIGRFAQRLVEYf +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus pyridinivorans TaxID=103816 RepID=A0A495NEP1_9NOCA +----------------------------AATL-SVRGDERVVLASVYKLPLFLAFCAEVD +AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT +TTVEELLARLGLTRTRIIGGTADVYQAYDPAYTSATIPEEMTRLLETVWSGSVLSPESTA +FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces sp. CEV 2-1 TaxID=2485153 RepID=A0A3N1TNT1_9ACTN +-------IRSMFDDAGVRLHVAELHRPSAQV--VIDPDEQLPLGSVYKVPLMVAFCRLAD +AGRIDPCRRLTLEAADRVAPTGVSVLHDPVTMSLRDLVTLMMTISDNTAAAAVLRVV-GP +DVVDAVCRDLGMPDTRIHGGVVSTFSVYDPAFKASSTPADMARLLRAIWTGEAASDDRCA +FMRDAMRRQPW-THRLASGFPDDVTVYGKTGTFGS-LRHEAGVVELADGSTYTAVVFTQA +ARADLPRADAVIGAAARVAVE-- +>[subseq from] serine hydrolase n=1 Tax=Pontibacillus yanchengensis TaxID=462910 RepID=UPI00136E94EA +--RLENEVTEIVSKLDGNASVVIQTI--NGTI-AMNEKEVMPAASVIKIPIMMEAFRQAK +TRGVDLSATVTIPQHNKVGGAGVLQFLSQEAFPLHDLVTMMIIVSDNVASNAVIKHI-GI +GNVNHLIEELGCSNTKLRREFMDLKAQ-EQGLDNTTTAEDMVKLLEQLTLQD-------R +EMVEILKGQQL-TSQLPAHTYEDLEVANKTGELD-GVNHDVGILIDSHQ-TVYVAVLLND +VR-DTVEGQRAIADIGNQVMQY- +>[subseq from] DZANK-type domain-containing protein n=1 Tax=Lactobacillus brevis TaxID=1580 RepID=A0A1W6NG22_LACBR +--EIKKDIGATVGAIGGTNSVYVSPVNSEQSV-VV-NNGSQRSASSIKIYIMVTAYAMAK +EGVFNLNDTHTLTNDEKVGGTGVIQNMRAGTLSYREIIEYMIDDSDNTGANIMIDKLGGF +QLINNKIKSMGATDTKLRRKMLDTK-ALDNGRDNTTSARDMGTTLKMIYNHHLVSREADD +EMLAILRKNQN-RTKLPNQLPSTATVYNKTGEYDYGVQNDAEIVRNSQGA-FVAVVLSED +GEET--DQLAAMNKLGLM----- +>[subseq from] Uncharacterized protein n=1 Tax=marine sediment metagenome TaxID=412755 RepID=A0A0F9QNK4_9ZZZZ +-kKLEKGLRELVGEFNGDVGIYVYNLKTGKVA-EINADTIFPTASIVKVPILVGVFEQIH +NGKLHLNDSLLYTAERVYGGSGLMQFYKDSTTDIRTLASLMITVSDNTTALWCQELAGGG +EAINKVMADLGLKSTRVNSRTEGRTIDWEKYGWGQTTPREMVSLLLKMRNRELVDEVSSD +EMYRLLTNSFYTDYSL-SQIPPYVQTAAKQGMVDR-SRSELIMVNAPNGD-YAFYIATKN +NQDEDNEAWQLQREVSAYLWHYf +>[subseq from] Beta-lactamase n=2 Tax=Flavihumibacter sp. ZG627 TaxID=1463156 RepID=A0A0C1I8Y3_9BACT +-------VTEFNKQPQAVFAVAVKDLSSGNTF-LYNDQLEFHAASTMKTPVLVEAYKQAK +EGKFSLSDSMLVKNSSIVDGSLYSYSKIGARLPISDLLYKMITKSSNLATNLIIDLV-KA +PNVNASMRKLGASKIQVLRGVEDGK-AYAKGLNNITTAYDLMLIMEAIANGTAVDKKSGE +EMIKILMDQYF-RDIILAKLPTDVKAATKSGNIT-AVCHDSGIVFLPDGRKYVIVLLSKG +IPQ-QSVATEILSTVSRIVYDH- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A3D8X5S5_BACME +---------------RSNNGLIRIHIEGKESI-QVNSFIQQRAASTIKLLLAIEAFRQID +EGILTLTSVIQRTEKNTVGGAGVLRALPRLTIKVKELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGVDNYTCASDVVKCLREIYEGNLLKKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Pseudonocardia sp. MH-G8 TaxID=1854588 RepID=A0A263DQZ0_9PSEU +--DLEREIRATFADAGVHGRLHAVPLGGSREV-GVDPDEPVVMASVYKVPLLVAFCRRVD +AGELDPREQVTVEPAERTAPSGLSVMRDPVTLSWRDLACSMITVSDNAAADVVLRRV-GL +AAVLEVLHDLELRHTRVHGGTAEVLRAYDAALDSATTARDMTRLLAAIWGDRAASPGQCA +FARDLLGAQVW-SHRLRSGFPVGVRVAGKTGTLG-AVRNEVGVVEFDGERPVAVAVFTRA +ARAELPRADAVIGQAARLAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E3MSF0_9PLAN +-----HELDATAKKFAGRVGFFVRDLASGADY-GWNPDERFPPASVIKLPVMIELYRQAA +AGRLDLDQRLRLPTDISTHGTGVLKKRDRPVLPVREYADLMMIHSDNMATDFIIRTV-ST +ATTNRFLDAQGLRNMRVSLELGRWHYYSDSLQNNVCAPRETVLLLERLYKGQLTSEKHKQ +AILGPMRASTH-KDTIARHVKDGIQVANKYGGSQR-ISADAGIVEITDR-PIAIACFALA +NDQADRSGREVLAEMCRLAI--- +>[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2D7NVR0_9BACT +-eDLDLKIKLLLEQIEGDFAIAFQDLHRKENNfFLNENKKFHAASTMKVPVMIEMYHQAS +QGKFSLTDSILVKNESIVDQSSYEYSQIGKKMTLFDLMYQMIILSSNLATNILVEEI-GS +KNVTASMKRLGAYNTEILRGVEDQK-AYDLGLNNVTTAKDLMTILKSIAVASSEITKDQI +AMINVLKAQEF-NDIIPRFLPLDVEVAHKTGSIT-GSHHDAGIIYLPNGE-IYILVLLSK +NLKDFNQGTLTLAKISKLFYEH- +>[subseq from] DZANK-type domain-containing protein n=4 Tax=Lactobacillus brevis TaxID=1580 RepID=U2NZB4_LACBR +--EIKKDIGATVGAIGGTNSVYVSPVNSEQSV-VV-NNGSQRSASSIKIYIMVTAYAMAK +EGVFNLNDTHTLTNDEKVGGTGVIQNMRAGTLSYREIIEYMIDDSDNTGANIMIDKLGGF +QLINNKIKSMGATDTKLRRKMLDTK-ALDNGRDNTTSARDMGTTLKMIYNHHLVSREADD +EMLAILRKNQN-RTKLPNQLPSTATVYNKTGEYDYGVQNDAEIVRNSQGA-FVAVVLSED +GEET--DQLAAMNKLGLM----- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00112BC0CF +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILTLTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVKKGIDNYTCASDVVKCLREIYEGNLLQKSSSE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-PYYAVVLIDG +LS-DNEQGRRLIADIGYLL---- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophaga pinensis TaxID=79329 RepID=A0A5C6LW49_9BACT +-hKLEKGLREIITGFQGDVGIYVRNLKTGRYV-DINADTIFPTASIVKIPILVGVFDKIE +KGELTYHQPLIYRDSIKYGGSGLMQFFKDSTTDLSVLVALMMAYSDNTTSLWNQALAGGG +QRINELMAQYGLNVTRVNSRTPGREAIRNVYGWGMTTPREMAELLVKIRNGEVISQNASS +RMYRLMTHGYY-DEVGLSQIPPYTQAAHKSGSVD-ASRSEVILVNAAHGE-YVFYVGTKN +NKTSENEAENLIRKVSAYLWEYy +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A3D2XD55_9BACT +-kRLQQKISQLIQGFNGDIGIYVHDLKKNKTV-AMNADTVFPTASMVKVPILVGIMDKIS +KAELDYHQTLTYKDSLLYAGVDILGSFKNDEIELSKVMMLMLTTSDNTASLWLQGLAGTG +TRINEIMDSLGFKDTRVNSRTPGREANRTQYGWGQTTPKEMAQLFERIAAKQILGDTASE +KMLKLLGRNYW-DEEGLSSIPAGIFVASKNGAVN-ASRSEVIYVNG-GEARYVFCICTKN +NKDQNNEAWVLTRKLSELLWNYy +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. FJAT-27238 TaxID=1679167 RepID=A0A0K9MLN0_9BACI +--ELEKRLSAIIGQAEGTWGVVVEEHGSAKRF-EHVPDELFIAESVIKVPIMAAVFAASE +QGHFRMDDQLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLI-GK +DQIDQTMINLGMRQSCYSRKLMIYPLD--ITENNKITAGDVASMLGHLATGSFLSQRACK +EMIAIMKKQQV-RNGLPSQLPPGWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD +VT--AQSALNTLGLLGRAVYDY- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces gancidicus BKS 13-15 TaxID=1284664 RepID=M3DYC6_9ACTN +----VARIHAAFADAGVTGRLHALDIDSGDQL-GAGADQPVCTASVHKLCLLVALHERAA +RGVLDLAEQLETVPGERTAPTGVAAMLDAARLSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTARLGLTRTRAVHSFGDMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Uncharacterized protein n=2 Tax=Oscillibacter sp. 1-3 TaxID=1235797 RepID=R9LYG3_9FIRM +---AKERILEKIKTFPGQSGIYYQNLETGETW-GYGDKDPYLAASIVKLPLMAAILLWRS +RGETSFDDKVTIREDQKIPGCGAVQFLNGDVLTVGELCRLMIVISDSCATNALFRHY-GA +AAIRKAFLELGLAGTQFNREYWDEERE-KQGINNYFVPEEMGRLLRRMYDRTLVNAESSE +WLENILRQQQI-NHKLGGKLPMDFPMAHKTGDEED-KAHDVGIVFTKS--PFIACFAYVG +P--DMQDYEDFIRRAARMLAD-- +>[subseq from] serine hydrolase n=1 Tax=Segetibacter sp. 3557_3 TaxID=2547429 RepID=UPI0010589E0C +-rKLERKLNQLITGFNGQLGIYVHDLKRNRIV-GISQDTVFSTASMVKVPILIGIMDKLN +RGELKYNQEIIYHDSLLYAGSDILGSFKSGEIELGKVIMLMLTTSDNTASLWLQNLAGTG +SRINNLIDSLGFKETRVNSRTPGRESIRSVYGWGQTTPKEMATIMERIVKGEIISDSLSQ +RMLRLLGRNFW-DDNAIAQVPADVFVASKNGAVNK-SRSEVLFVNGRGR-RYVFCVCTQN +NNNENNEAWVLTRKISKLLWEH- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces varsoviensis TaxID=67373 RepID=A0A0L8QRD0_9ACTN +----QRTIRGMFADAGVRGWLHVADLHRPAACvTIDPDEPVPIGSVYKAPLMVAFCRLAE +AGEIDPCRRVTLGPADRLPPTGISILRDPVTVSLRDLVVLMMTVSDNTAANAVLRLV-GT +AAVDEVCRALGMADTRVHGGVATTFAVYNPLSKASASPADMARLLRAIWTGRAASPESCA +FMREVMGRQAW-SHRLGSGFPDDVRVSGKTGTFGS-MRHEAGVIELPDGSAYTAVVFTQA +ARADLPRADAVIGAAARTAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC712 TaxID=1848329 RepID=A0A4R4WF71_9ACTN +------DFDALFRTAGVNGWLHAVDVDSGREI-GHGADVPLPTASMFKVPLLVEFCRQAD +AGLLDPAGRMTVPAAGRSSPTGISAMLDEVTLSLRDLAYLMIAVSDNGSADVLLARV-GR +KAVNTMLAVLGLHGTRVLQSCQEFNDALDPERTNRSTPREMAELFGLIWRNEAASAESCA +WMRAALNKQVW-PHRLASGFPDDVAVSGKTGTAPT-LRTESGVVEYPDGRRYAVAVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus planocerae TaxID=1737569 RepID=UPI000C7F656D +------------RGFGGEVGLVVSDLAGRELY-VLNPDRVFPAASTIKVPLLVQALGEAQ +SGRLDLRERVTVEAGDRVPGSGVLHELGPGLPTWEDVLTLMIVVSDNTATNLVIGRL-GV +EEVGAWLAEQGLSGTRLVGQLERRNEAQRRGERNRTTARDQVTVLGGLARGELLDPFHTD +LALSILSRQQF-RDILARHVPRGYRVASKSGELT-GVRHDVGVLFTP--RPLVVALLSEG +GDDPRE----------------- +>[subseq from] Serine hydrolase n=1 Tax=Selenomonas sp. mPRGC5 TaxID=2593411 RepID=A0A5D6WAB0_9FIRM +--ALAASLRQLMEKDSAKYQVYVFFPQWDEPL--VMGKDPQSSASIIKIFILGTAYELAE +QGQLDLNQQVTVHPLDMVGGAGVINGQSGAPYTVRKLLELMITESDNTATNVLMDAI-GL +ERIHHFMKEHGFHDSILQRKMMDYE-ALRAGKDNFTTAADAGRFFRLLREHKLVGEAADS +EMISILFGQTD-TECFPQALP-QARIAHKTGELS-GVYHDAGIVYDAND-SYVLCIMSTD +SRGR------------------- +>[subseq from] serine hydrolase n=1 Tax=Fibrella aestuarina TaxID=651143 RepID=UPI00141A3321 +-tKLTQKLTEALRGFRGDVGVYVHHLKTGKTV-AINADTTFPTASTIKIPIMIGLFDQIE +KGKIGYQQEVVYRDSLHYDDGIVGSLKDGAKLPLSEVVMLMETVSDNTGSLWCQKLAGGG +IAINAWLDTNGFPQTRMNSRTPGREAYQKRYGWGQTTPRELADLLTYLRQGRAISPDASD +RMYRNLCRQFW-DNDGLSQLPVEVKVACKTGAVNQ-ARSEVVLVHAPHGE-YVYCVMTKN +QKDETNEGFTLLRTVSALIWQHf +>[subseq from] serine hydrolase n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=UPI0005C82F10 +---LENKIQEVMDLCNGRVSVAI-DLPT-QSI-QINGDRSYSAASLIKIPILLEGFRQSE +EGKISLCEMVTVPKEGRVGGAGVLAALSENLLTIEDLLTLMIIVSDNTASNLLIDRL-GS +NAIQELCNSLKLKHTKLHRKFMDFKA-MEQGLNNVTSALDMISCLKVMDNSPEFSQTSRE +KMLHILHQQQF-DNKLPSRMDREVFVANKTGELP-GIEHDCAILKLGNKT-AYIAVLIDE +LGEN-GSGKDTIALIGKLIFD-- +>[subseq from] Putative beta-lactamase related protein n=1 Tax=Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL B-2516) TaxID=278992 RepID=A0A0K2AUX2_STRA7 +-------LHAAFADAGVTGWLHAVDIDSGAQV-EHGPDQPVCTASVHKVCVLVTLHELAA +AGALDLTERVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLGRV-GL +DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLSALWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT +ARATLPAADAVIGTAARIAVD-- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=mine drainage metagenome TaxID=410659 RepID=A0A1J5SM31_9ZZZZ +-kHLQSSIQNLLTGFHGQVGVFVHDLKKNKIA-AIDADTIFPTASMIKIPILIGVMNKIE +SGELQYHQPLIYKDSLLYAGVDILGSFKNNEIELSKVMMLMLTMSDNTASLWLQSLAGGG +LRVNELLDSLGMKVTRVNSRTAGREKNRTEFGWGQTSPREMASLMEKISQGEVINQTASE +KMLRLLGRNYW-DEEAISQIPTDVFIASKSGAVD-ATRNEVLFVNGKHC-CYIFCICTKN +NKEPNNEAWELTRKLSKLLWEYy +>[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SZF4_9BACT +------------------------------------------------------------ +------------------THSPLRDANPNGNITVGDLLKYSLIESDNNACDILFKYIGGP +LVTEKYIHGLGIKDVAISQTEAKMMESEDNCMLNWTKPSAAVLLLETFLQNQMFSKNEVL +FLERAMADCKTGNNKLKAGLPKQVLFAHKTGSSGRNADNDMGFVVFPNGQYYTIAVFIMN +SRETDQENAKIMADISRTVYEYf +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00119EF3E6 +-----------TKWKQSNNGLIRIHIEGKESI-RINSFIQQRAASTIKMLLAIEAFRQID +EGILTLTSVIQRTEKNTVGGAGVLGALPRLTIKVEELLTLMIIVSDNTATNELISLA-GF +EKINECARNMGLKKTVLNRYMMD-ETAVKQGLDNYTCASDVVECLREIYEGNLLKKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LSEN-EQGRRLIADIGYL----- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E1WA46_9CHLR +--KLNFSVNNIVNEFKGLCGVSIYDPDTNWYL-GINDEMIFPTASSIKIPILIKLLSDAD +KKLVNLSDEIIITEEMKSRGSGVIHKMTGSVMTIENLAILMINLSDNTATNLCIDIA-NQ +KEINEMLSSYDFGTMKLNRKMQDYQ-AINEGKENIATPKEMNMILQMLDNKSLFNESVSN +KTLDILAINKS--TPISQPLPENIKVAGKTGGMP-GVRCETAIVXLXNX-XYILTVMTSY +GGQSEXPQN-------------- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3B9Z620_9CHLR +------------------ASIAVVHLETGASA-TVNGDRIAVPASLYKVGVLVEAFRQIE +AGLLRLDETLRLLPIDWAPGAGILQGRIGTQVTITDALRLMIGISDNTAAHAIVRRI-GV +DRVNANNQRLGLSNTRY----------YIDDRPDTTTAADMARLLSLLATGRLAGVEATG +QMLDLLQQVQP-AAWLPRGVPPTIAVAHKSGQLD-AVRNDAGIVFGPTGR-YVVVVLTDN +RP-NAMKGENAIVQVARSVHAYf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces ambofaciens TaxID=1889 RepID=UPI0007B424C8 +-------LHAAFADAGVTGWLHAVDIDSGAQV-EHGPDQPVCTASVHKVCVLVTLHELAA +AGALDLTERVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLGRI-GL +DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLSALWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT +ARATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000CA3A2D9 +------------------NGLVRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKEIDNYTCASDVVKCLREIYEGNLLQKSSRE +RIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNAQGRRLIADIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SBST2-5 TaxID=2720025 RepID=UPI0014387480 +----LTRIRAAFADAGVTGRLHALDIDTGAQL-DEGADQPVCTASVHKLCLLVALHREAA +AGRLDLTERVDCPPDARTKGPTGLAVMLDSALSLRDLAYLMIAVSDNAAADLLLGRV-GL +DTVNAATDRLGLTRTRAVHTFGEMLAALDPARTNRSTPREMTRLLAAVWRDEAGTAEHCA +AMRRLLALQVW-PHRLASGFPDDVHVAGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRT +ANAALPAADAVIGTAARLAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Arachidicoccus sp. B3-10 TaxID=2545455 RepID=A0A5P2G9C5_9BACT +-rKLEKKLAPLIQNFHGTSGIYVENLKTGKFV-AINADTIFPTASIVKVPILTTVYQKIL +DGKLTYNQKLIYKDSLKYGGSGFAQFFKDSTMDIATAAALMIDYSDNTTSLWLQSLVGGS +DTINAVLDKLGLKDTRDNRANREANRKIYG--WGQTTPREMATLLKDIYLKKILNPAACE +SMYRTMSHVYY-DNFALSQIPPFIQTASKQGMVDE-SRSELVMVNAPHGD-YVFYIATKN +NQQSNNEAWQLARAISKLLWHYf +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus erythropolis TaxID=1833 RepID=UPI00030573FB +--SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPIVLQYAREVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodothermaceae bacterium TaxID=2026787 RepID=A0A2E3R240_9BACT +--ALQARLDALADGFDGVVGVYLRHLPTGREA-TLRPDDLFPTASIVKVPILVGVFEQIE +AGTLALDTELTFRDSLRYGDSGFAQLRDSSTVYLHSAVEQMLAASDNTASLWLQGMV-TG +EAINAWLAAEGFEGTRVNSRTAGRRGDWERYGWGQTTPREMAELVRRIVDGEAVSPAADL +EMHRLLTRTHY-DDEAIAALPPSVQVASKQGAVSQ-SRSEVAYVHAPSG-PYLLMVVTKE +QAAPDNAGYDLIRAVSRLAWETf +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus pentosus TaxID=1589 RepID=UPI000B5455B7 +--QIRNDINSTVGAISGTNSVYVSPVNSKQTV--LVNDGAQRSASSIKIFIMVTAYAMAK +EGVFNLTDTHTVTDSEKVGGTGVIQNMDAGTLSYQEIIEHMIDDSDNTAANIMIEKLGGF +DLINNKISNMGATDTKLRRKMMDTK-ALDDGKDNTTSAHDMGMTLKKIYNHQLVSRQADE +EMLTILAKNQN-RTKLPKDLPSSATVYNKTGEYDYGVQNDAEIVKNSHGA-FVAVVLSED +GDQ--NDQIDAMNRLGSLLYQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Oryzihumus leptocrescens TaxID=297536 RepID=A0A542ZJZ9_9MICO +---LAEEIRSVIRRAPGTLGVVVQD-PSGVLV-DLEGDRVVPSASTIKVLVLVAALRRVA +DGRSRMGDLLDLPAAERVGGSGPLQALGSVTLRLGELLELMVTLSDNDATNVVLDLV-GP +DGPAAVAAGLGLADTRLQRRMMDFAAR-EAGRENLTSARDLAALVAALRRGEALPPDQTR +DALELLGRQQL-RDGLPALLPPAVVCGNKTGELP-GIRHDVGLLECDGRW-AAVAVTAT- +----------------------- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7FM18_9BACT +------------------------------SI-LIDANLRFHAASTMKLPVMIQIFRDAD +AGLLRLDESLTVHTASLVEGAFIVYALVGRNRSVRDLLERMITRSSNLATNILIERV-GA +DRAQRTARALGAWSIQVLRGVEDGA-AYRAGLNNTTTARDLGVLLQAIATGRAASGAACD +SMLAILGRQEF-NEGIPVGVPPAARVAHKTGWIGEVVYHDAAVVSPPRGGRYVLVVLTGG +IKED-SIAHNLVADLSRLVYE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Nocardia fluminea TaxID=134984 RepID=A0A2N3VF10_9NOCA +---------------------HARRCDSAGEV-SVGGNDRVVIASVYKLLLLAAFLRQVD +HGLIDPAGRLTIDPSDCTPPTGLAALHDPVTLSRRDLAMSMMTVSDNAAADVLLGEV-GL +AAVGELVHELDLPDTRIIGGTADQHRAYDPSYASATTPEEMTRFLWKLWSGDILSTASTE +FARTVMSKQVW-PHRIAAGFPRGVLVAGKTGTIGV-IRNEVAVIEFPGETPVAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea fuscirosea TaxID=1291556 RepID=A0A2T0N7F7_9ACTN +------DFESLFRTAGVTGWLHAADIDTGREI-GIGSDDPLPMASMFKVPLLVALCRQAD +AGLLDPAERITVTGAGRSPPTGISAMLDEVTISLRDLAYLMIAVSDNTSADTLLARI-GQ +DTINAMLDSFGLDGTRVVQGAGESVDALDPARSNRSTPREMTRLFGLIWRDEAASAASCA +WMRGVLNAQVW-PHRLASGFPDDVAVSGKTGTLPT-LRCESGVVDYPDGGRYAVSVFTRS +FSLNQPRADAVIGTSARMAVDH- +>[subseq from] serine hydrolase n=1 Tax=Chitinophaga vietnamensis TaxID=2593957 RepID=UPI001177FEDE +-kQLADILTPMLQSFHGQAGIYVHHLPSGKTV-AINADSVFPTASMVKIPILIGVFNKIA +KGELQYRQLLRYRDSLLYAGEDILGSFKDSEIYLDKVVMLMLTMSDNTASLWLQSLAGGG +TEINKWLESNGFVNTRVNSRTPGREAIRKVFGWGQTSPREMATLMEKIYKGEVISKAASE +RMYRNLTRNYW-DTEGVLQVPPNVRTASKNGAVDE-VRSEVIMVNAPHGD-YIYCITTKN +NAKRDNEAWQLLRKVGAAIWKHy +>[subseq from] serine hydrolase n=1 Tax=Microtetraspora fusca TaxID=1997 RepID=UPI00082A36D9 +-----KQLEQIFRTAGVTGWLHAVDIDTGREV-GLGADEPVVLASVFKVPLLVAFYRQAE +RGLIDPAERVTVSAEGRPGGTGVSAMLDEVTASLRDLAYLTISVSDNASADTLLARV-GL +DEVNAVLADLGLSHTWVEHSCAELFTVLDPARTSRSTCRDMTRLLGMIWRDEAAGPASCA +AVRRLMGLQVW-PHRLASGFPDDVAVSGKTGTLPT-VRNEVGVIEYPDGGRYAIAVFTRS +IGQNQPRADAAIGTAARVAVDH- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus sp. 33-7 TaxID=2486003 RepID=UPI000F7B4ABE +-------------GIKGDTSAFYYDLNNNDSA-SYGDDEPQRAASDIKVYIMAAAYQKID +DGDMSLDGRYELTSEDKVGGTGVVQNQVGDSLTYRDLIDYMITKSDNTAANIITKEIGGL +DAVNDEIDELDLRNTKMERMLMDQD-ALSEGKDNMTTAHDLAMFMRKLYHHDVVSDKYDK +QMLSILSNTSN-HSKLPANINTNVDVYNKTGEYQYGVENDAAIFKRGNKA-FVLVVMSQN +GDSD--EQKSAMGSLGKQVTQ-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus qingshengii TaxID=334542 RepID=UPI0007AEB259 +--SAQQEIAAVLAEAKTDAYVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus plantarum EGD-AQ4 TaxID=1382301 RepID=T5JTR1_LACPN +--QIRNDISSTVGAISGTNSVYVSPVNSKQTV--LVNDGSQRSASSIKIFIMVTAYAMAK +EGVFNLTDTHTVTDSEKVGGTGVIQNMDAGTLSYQEIIEHMIDDSDNTAANIMIKKLGGF +DLINNKISNMGATDTKLRRKMMDTK-ALDDGKDNTTSAHDMGMTLKKIYNHQLVSRQADE +AMLTILAKNQN-RTKLPKDLPSSATVYNKTGEYDYGVQNDAEIVKNSHGA-FVAVVLSED +GEQN--DQIDAMNRLGSLLY--- +>[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. ERMR1:04 TaxID=1705393 RepID=A0A0N0LHA8_9FLAO +-kELSNNIHELISNKKLDIGISIRDHSGDEIV-SVN-NKKYKLYSVSKLFLAVYILNQVD +KGKLNLNQPILFSKKDLKPYSPLRDSIPQGTLSLKQSLKFMIKSSDNNVFDKLAVASGGL +SNLNIFIHQTFKATKDQFSIMHDYSSSQRDFESNIITPSMATEILYQLEKKEILSDHSYD +SLKNYMEHSVI-NTRIQGLIKKDTQSFHKSGTSNREACNDIGIVNLKNGKSFMIAVFISN +SKEDDATNDSLIAKITELAYT-- +>[subseq from] Uncharacterized protein n=1 Tax=Planococcus halotolerans TaxID=2233542 RepID=A0A365L268_9BACL +----EFQVKKALEHSSGKVSLAIET--KNGRI-DINSHKQMKSASTIKLAVLLEAFSQID +RDLVKPYDIIRLQPEDFTQGSGVLFHLGSVKLSFEDLLTLMIIVSDNTASNLVIRTV-GI +DRVNALLNRLGCNETVLGRQFMDIQAALD-GLDNFTSAADLVTMLKAVDSGELLSEDSRR +RVLHILKKQQL-LTNLHGRIDDEVSVASKSGSLP-GVVNDAGIFEYRGDK-VYAAVLVSD +SP-DNHSGQEVIAEIGGYIYD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-475 TaxID=1463910 RepID=UPI0004C89992 +----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA +AGVLDLTEQVECSPRDRTTPTGVAAMLDGARLSLRDLAYLMMSVSDNAAADLLLHRV-GL +DAVNRTTARLGLSRTLAVHTFGELLAALDPARTNRSTPRDMTRLLAAVWRDEACTPEHGA +AIRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT +ARTSLPAADAVIGTAARLAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus megaterium (strain DSM 319) TaxID=592022 RepID=D5DD93_BACMD +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILDLTSVIQRMEKNTVGGAGVLKALPQLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Bacteria TaxID=2 RepID=UPI00068C3C1C +---LRDYAENEIQDINAKVSLLVYDFDQDETLlSFHEKDRVVSASTIKTPILLTALDMVQ +SGKLSVGQMLRLPGEEILDDTEVFDRGVR-EYPLEELLTWMIINSDNTATNVLIEFL-GM +DAINACCRKLGLKATVLERKMLDWE-AIRQGRNNYTSAQDQLTVFQSLRRASILTPELCR +YALGILERQRDFSMALRYISDRDFSAAHKTGGLDY-LNHDTGIFSLPGHE-YYFGCFVTD +STDDTDENKKLIGRLSRKVYDYy +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. HB172195 TaxID=2574798 RepID=A0A5R9F7G7_9BACI +--QLESEIKTIIKELPGDYSIVIETLEG--TI-SLKGENQLPAASLIKLPIMIEAFRQSE +ANIIDLDEIVDVSTVKKVGGAGILARLSSIALTIRDLLTLMIIVSDNTATNELIDRL-ST +DKINNLCRAYNCQSTRLQRKLMDFE-ALKNGKDNLTSSKDVVKLLKGIDTGQDYSKRTRK +EMLSILSEQQF-LDKLPAFIPEEFFMANKTGELP-GVEHDAAIIKSNGK-HVYACVMFAN +LYE-NKEGKVAISEIGRAIWE-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF6955A +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKDLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLKMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3D3JED1_9BACT +-hNVQTKLDSIVANTPAHIAVKAIVLDTLAEY-AVHERDTMVSMSVIKLPMVCAMLEGVS +QGRFLMSQPVLVSAEDAVRHSPLRDSAGNGPTTLGRAMSAAVCLSDNIGIDVALDATGGL +SAAQSFFRNHGLDGIGAGTTYRDMGQK--GATANWMTARSMTDMLYRLHRAELFPAAERN +WVLRELSTTPTGKRRIRGLLPDSVVVAHKTGSHYARAVNDAGIISHPTGKFILITVLVND +SKLTPLQTEDVIARIARTIYD-- +>[subseq from] Beta-lactamase-like protein (Fragment) n=1 Tax=Streptomyces coelicoflavus ZG0656 TaxID=1120227 RepID=H1QTA7_9ACTN +-----ARLEAAFADAGVTGWLHAVDVDSGAQV-GVRADQPVCTASVHKLCLLVTLHELAA +AGALDLTEQVECPPDGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL +DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEAAPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Fibrobacter sp. UWH1 TaxID=1964354 RepID=A0A254RS05_9BACT +--------------------------STQKSA-GLNESLHFPMHSVMKFPQALYVAHFLD +SAKIGIDAKVRVVKAELMQWSPMMKEMGDTAVSYAELLQWSLVQSDNNASDLLFKFCGAP +EKITRYIAKLGFKDIQIGATEAEMHTDLAKSDLNWSTPKEMSNLFEWFYKNKD-KTANLQ +FIWKTMSEVETGKDRIPAAAPAGATVVHKTGTGFKDPMNDAGIVILPNGQVQFIAVFVPE +PTAPNQ----------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CCM_MD2014 TaxID=1561022 RepID=A0A0N6ZLC7_9ACTN +--ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQAVCTASVHKVCVLVALHELAA +AGELDLTEQVECPPAGRTPGPTGLAAMLDPALSLRDAAYLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPAEYGA +AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEIGVVEYPDGGRYAVAVFTRT +ANAVLPAADAVIGTAARIAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=A0A0K9YK59_9BACL +--EIEKRLGEIIAEAEGTWGVVVEELGSGHDF-KHLPDELFIAESVIKVPIMAAVYEAAD +KGQFSVEDHLTLRKEDLVGGSGFLYRLSPGLLTIRDLITMMIIQSDNTATNMLIDLV-GE +EQIKQTMCNLGMSQSRYSRKLMIYPV--DVAENNLITAGDVASMLGKIASGTFLSQRACA +EMIAIMNKQQV-VNGLPSLLPHEWTLPCKSGWDT-GRQHDVGVLYTAGR-RITITALSQD +VQPG--AALRTLGLLGKAVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Geodermatophilus sp. DSM 44513 TaxID=1528104 RepID=A0A5S4ZKS3_9ACTN +------------------------------------------------------------ +----------------------------------RAAAEAAVRHSDDTATDVLLDLLGGP +QALDAAPETIGDDVTRVDRTEPTLDDTVPGDPRDTSTPRGLAGDLRARPRRRAGSRGPRP +-PVGWLTTTTTGDARVWAGVPAGWVVGEESGAAAYGTRNDTAVVRPPRRAPIVVAVLSDR +DEPDAGHDDALVAEATRAVVA-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus erythropolis TaxID=1833 RepID=UPI000BB34E82 +--SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +ENIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWKDEAGPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Deinococcus aerius TaxID=200253 RepID=A0A2I9D6D4_9DEIO +------------HGYAGEVGVLITDLAGRGLY-ALNSGRVFPAASTIKVPLLVRALQEAQ +AGRLDLRERVTVREEDRAGGSGILHEFGPGLPTWEDLLTLMIVVSDNTATNLVIDRL-GV +ECVNGWLDGLGLGGTRLVGKLERQNEAQRRGERNRTAARDQVNVLGRLARGELLDPAHTA +LALSILSRQQL-RDILGRHVPRSYRVASKSGELP-GVHHDVGLLFTP--RPLVVAVLSEG +GL--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus actinosclerus TaxID=1768108 RepID=A0A2Z3YVT2_9DEIO +----------VAAGFAGVVGLHVTDLAGTELA-AWNAGWVFPAASTIKVPLLVLALQEAQ +AGRLDLSGRVVMQPGDRVPGAGVLHELDGGLLTWRDVLTLMIIVSDNTATNLVIGRL-GV +DAVNTWLAAGGLTGTRLVGKLEQRTEAQRRGERNATTARDQTALLRALVAGEVLDEAHTA +LALDILGRQQY-RDLIARHVPCGYCSATKSGELH-GVHHDVGVLFAP--RPLVVALLSEG +GADPRE----------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Nocardia neocaledoniensis TaxID=236511 RepID=A0A317NUX9_9NOCA +---AAERIRAVFADAGCTGWLHARRCDSGDEV-CVGGSERVVIASVYKLLLFVAFCREVA +GGRIDPRARITVDPAECTPPTGLAALHDPVTLSRRDLATSMMTVSDNAAADVLLGEI-GL +AAVTELAAEVGLTETRVVGGTADQHRAYDPSYASATTPEEMTRFLRLLWTGRLLPAEHTA +FARTVLGRQIW-PHRIAAAFPRDVLVAGKTGTIGV-IRNEVAVVEFPGETPVAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. SAI-097 TaxID=2485145 RepID=A0A3N1DNQ3_9ACTN +--AVAARLDAAFADAGVTGWLHAVDIDSGAQV-EAGADQPVCTASVHKLCVLVTLHELAA +AGELDLTERVECPPDGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL +DAVNGTTARLGLTRTRAVYGFAEMLDALDPARTNHSTPRDMTRLLGALWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. CNU-125 TaxID=1904961 RepID=A0A1Q9SUM9_9ACTN +----PARIEAAFRNAGVTGCCHAVDIDAGRDV-GVRADEPVVLASVFKVPLLVAFHRRVA +AGTLDPTERATLPAADRTSPTGVSALLDDVRMSLRDLATLMITVSDNAAADFLLDRV-GL +AAVNAAAADLGLPATFVAGSGREMLDVRPLDPTSRSTPREMTRLLSLVWRDEAAGPGECA +AMRRMFGLQVW-PHRLSSGFPEDVVVSGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRT +PVAVHPQGDAVIGTAARIAVEH- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E5NZB0_9CHLR +--------------HRGDVGISVQS-PAGEVW-SRQGDIQFPAASIAKIPIMITVYRMID +QNRLALDNEYILQNIDKSNGSGVLRHHTGIVLTLADLIFLMISISDNTATNILIRKV-GM +DLISATMKELRMSSSNLSRYFVGRL-AIEGEQENYATPNDYVRVLDSIVSGEAASASSCQ +AMLATLSLQQN-RNRIGRYVPPDFRWGSKTGTNP-GITNDVGFVTSSLGT-MCIAILCRG +LK-SEVVGEQLIADSTRAAMQ-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535XYM1_9CHLR +------------ASLQGEAGAFASDADGHALF-CENEDELFPSASVIKLPLVMTLHADAA +RSLVDLDERVGVGE--RVDGSGVLRHMRDVDLSLRDLAMLAIIVSDNTATNRLIERI-GI +ERVGERLREWGCPKTRLSRKMYDFEAATR-GHENVMTPRETVSLLLRLQRGECEDRATSD +AVLAVLEQCQD-RTMLLRYLPYGAKAPHKTGTLDE-SRNDAAIV--PGDRPIIVAAFTRK +LRDS------------------- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. MH60 TaxID=1940758 RepID=A0A2S6WMD0_9ACTN +--ATAARLDAAFADAGVTGWLHAVDIDSGTQV-GVGADQPVCTASVHKLCVLVTLHALAA +AGELDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDTAYLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLGALWRDEACPPEYGD +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-1314 TaxID=1463882 RepID=UPI0004CBD848 +----VARIHAAFADAGVTGRLHALDIDSGDQL-DAGADQPVCTASVHKLCLLVALHERAA +RGVLDLAEQLETVPGERTAPTGVAAMLDAARLSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTARLGLTRTRAVHSFGDMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium paludis TaxID=1476465 RepID=A0A4R7D8U0_9SPHI +-kKLTNNLKELIAGFDGEIGIYVQHFKANKTV-ELSADTVFPTASIVKVPLLVGVFDKIN +AGELLLQANYRYRLERAYGGSGLMQLFKDSAIDLSTMISLMLTYSDNVASIWCQELAGGG +QAINPLMDRLGLKDTKVNSRTAGREKIWEQYGWGQTTPREIVKLMRMIEQEELFTPRLSS +KMYRYLKNQFY-NERSLSQFPAHIATASKTGSVD-AARGEVVFVHAPSGD-FAFAVLTKN +NKTRDNAAEELTRKIANLIWNHy +>[subseq from] Beta-lactamase class A n=1 Tax=Gelidibacter sediminis TaxID=1608710 RepID=A0A4R7Q8L0_9FLAO +-kTLENGLTELVKNFEGDVGIYVYNLKTQKEA-AINADTIFPTASIVKVPILIEVFNQIK +KGKLHLNDTMVYDAKRVYGGSGLMQFYKDSTTDLRTLVSLMITMSDNTTSLWCQELVGGG +LAINKTLADLGLEHTRVNSRTEGRTLDWETYGWGQTTPREMASLLIKMRNRTLVDDAASD +EMYRIMSNSFYTDYSL-SQIPPHVQTAAKQGMVNK-SRSELVMVNAPSGD-YVFYIATKN +NADEDNKAWELQRAISAYLWNYf +>[subseq from] serine hydrolase n=1 Tax=Dyadobacter beijingensis TaxID=365489 RepID=UPI00037FAA68 +-kKLTAKLETALAGFHGQVGVYVRNLKTNRTA-AVHADSLYPTASMVKVPIMCGIFDKID +QGEVKFDQELVYRDSLKYDNGIVGSFRDSTKIALPKVVHLMISQSDNTGSLWLQAMAGGG +ATINQWLEKNGFANTRVNSRTPGRKEFQARYGWGVTSPREMAELVAMIRSGKAISPAASD +RMYRYLGMQFW-DGEAISQLPSNVKIAAKSGAVNQ-AKSEVLVVHAPHGD-YVFCIATKN +QEQKENEGYALIRKVSAIIWDHf +>[subseq from] serine hydrolase n=1 Tax=Bacillus aurantiacus TaxID=254410 RepID=UPI0003F9AEBC +---LYSTIHKRVTELKGTYSIFIES--PRDTI-AMDENRVVPAASVIKLGIMIEAYRLID +EGQLNENDRITVRPSERVGGMGVLQHHSVESLSIGDLMTLMITQSDNTASNCLINML-GK +DQINHTIKRLGCTNTKLRRSFMDVESA-KRGVDNTTCARDMVAMLKALSNSEILTSESSK +KAIHTMKQQQL-RGKLPYRIESSFTLAHKTGELQ-GVEHDVGIMNVRGED-VYIAVLLDQ +LPN-NRLGKEAIGYIGEAIYR-- +>[subseq from] serine hydrolase n=1 Tax=Litoreibacter albidus TaxID=670155 RepID=UPI000AFF8F6E +-----EAVRGIERDLGARVGLYMHDLHTDEQI-TYAAHDRFPMNSTFKLLACGALLKRVE +AGEADLTQTVSLQGMEVVSYSPAIKEHMRKGVSLNDACGMVLSVSDNTAANIVLSQIGGP +DGLTTFLRSVGDENTRLDRWEPAMNEAIRAT----------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Asanoa ishikariensis TaxID=137265 RepID=A0A1H3UP96_9ACTN +----GAKLQAIVDAAPVTAGVSVRDLSGEQQI-SVAGRFRPKAASLIKLWVITELMRRID +CGQAAYTDTVLVLPTDVVGGTGELQHTFPQNVTLFRLAQYTIKYSDNTATNVLIDYLGGF +GPVNALADSMNQTQTVLARKMLA-----PAPPENFTSPDDVISLLGAVWSGNVLRQVNRD +LLLSFMLEQTL-NGKIPAALPSGVPVAHKTGELVD-VSHDVGYYLIPGT-EIAVAFLTAG +PE---ELGASTVRELARAVYDY- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus soli Cha et al. 2016 TaxID=1309411 RepID=UPI0012FF4F0D +-------------------GLRVTDVTGAELI-AWNAERVFPAASTIKVPLLVLALQEAQ +AGRLDLSARVTMQPGDRVPGAGVLHDLDGGLLTWRDVLTLMIVVSDNTATNLVIARL-GV +DAVNAWLAAQGLTGTRLVGKLQQRNEAQRRGERNATTARDQTALLRALVAGDVLDEAHTA +LALDILGRQQY-RDLIARHVPCGYRSATKSGELL-GVHHDVGVLFTP--RPLLVGLLSEG +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=UPI00130E1405 +---------KKLEQLPGKISFLYENLSTGDGF-AYHEQEPMMAASVIKLFVMAAAFEKEK +KGTFHMDEMFAVKKEDRVPCGALTYLHDGILVTGMDLVTLMIIFSDNTATNVLIDII-GM +EEINKIIRELGFRQTLLQRKMYDMERA-GRGIQNYITAYETGRLLKLMYEGTLIDRQSSE +TMISILKNQQL-CSKIPFYLQESPEIAHKTGEDT-GITHDVGIVYGK--EPFL-VCFCGN +ET-DTPAFERVMAEISLDLY--- +>[subseq from] Uncharacterized protein n=2 Tax=Rhodococcus TaxID=1827 RepID=C3JVC0_RHOER +--SAQQEIAAVLAEAKTDAYVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. D-46 TaxID=2716265 RepID=UPI0013F642CD +--SAQQEIAAVLAEAKTDAYVHARDIDSGEEF-DYGADEGVILASVFKIPVVLQYAREVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus yeomjeoni TaxID=291403 RepID=A0A327PD85_9BACT +-kNLESSIRALTDSFKGDVGIYIQNLKTGATV-EINSDTIYPTASIVKIPILLGLFDKIE +KGEISYREPLIYRDSIKYGGSGVMQFFKDSTTDLSTLIALMLSYSDNTTSLWNQALAGGG +AEINELMATLGYENTRVNSRTLGRESIWEKYGWGQTTPKEMADILIKLNNRELISKAASE +QMYRLLSNTFY-TDYAVSGIPAGVNVASKQGMVN-ASRSEVFLVNSPQGD-YVCAIFTNN +NEDKENEAWVMTRKISNLLWNHf +>[subseq from] serine hydrolase n=1 Tax=Pedobacter oryzae TaxID=1122943 RepID=UPI0003FDDBE1 +-kKLSQKLQELTQGFNGETGIFVQNLKTGKIA-VYNADTIFPTASMIKVPIMCAVFDKIE +KGELSYQQELIYKDSLLYAGEDILGSFKDGEIALSKVQMLSITTSDNTASLWLQKLT-GG +KYINQWLQTNGFTQTRINSRTEGREKDRALYGWGQTTPREMAGLLVKIRQGKAISPAASE +RMYRNMIRIYF-DQVALSQIPPYIQAASKQGAVNE-SRSEVVLVNAPHGD-YVFCVATKN +QKQANNEGYTLIRNLSALLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC310 TaxID=1848322 RepID=A0A4R4VJC9_9ACTN +------DFDALFRTAGVNGWLHAVDVDSGREI-GHGSDVPLPTASMFKVPLLVEFCRQAD +AGLLDPAGRTTVPAAGRSSPTGISAMLDEVTLSLRDLAYLMIAVSDNGSADVLLARV-GR +EAVNTMLAALGLHGTRVLQSCQEFNDALDPERTNKSTPREMAELFGLIWRDEAASAESCA +WMRAALNKQVW-PHRLASGFPDDVAVSGKTGTAPT-LRTESGVVEYPDGRRYAVAVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus erythropolis TaxID=1833 RepID=UPI001412387D +--SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus sp. TCA20 TaxID=1499968 RepID=A0A069D9B0_9BACL +---------------GVRVTVSVADLSGNLGF-SIGSEERYRSASTIKLAIACALLQMVD +RGEVRLEDQAVVRDKDVVGGSGSLQLEVMPLANIGRLAKLMIAQSDNTATNVLIDMI-GF +ERVNAMLEGLGIHRTQLARKMFAPVQS--PELDNYADAQELTYLLKLVYQGEVLSEYSRR +LLLLWMSRQEV-NTKFGAVLG-DILIAYKTGEAGN-VTHDAGYFLIPGRE-LAVAVMTEV +MTEAQRIGNPVVQRIGKVIYDQ- +>[subseq from] CubicO group peptidase, beta-lactamase class C family n=2 Tax=Micrococcales bacterium KH10 TaxID=1945885 RepID=A0A239II29_9MICO +-----------AASNNIRMGVSITDLADGDTI-TVGDQEPYKAASVIKLPLLAQLMDLAD +NGELSLDELVTIPESNIVGGSGTLRLREPLDISVRELMELMVQVSDNTATNVLIDRAGGF +DAINDYIAELGYETMWLGRKMI--HTAVPPLQENWLNSSEVTDFLVRLYEHDFLSAASSE +HIIDLMKGQLV-NTKFGAVVPRE-VLANKTGELGD-ASHDSGYILVEGREVALTATTAFA +APVTQAQANVYVQRAATFAYD-- +>[subseq from] Beta-lactamase regulatory protein BlaB n=8 Tax=Rhodococcus TaxID=1827 RepID=A0A1F2PWI9_RHOER +--SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] Serine hydrolase n=1 Tax=candidate division KSB1 bacterium TaxID=2172550 RepID=A0A6A0I0V6_9BACT +---LTKKVLQAIDGFKGEVGVYVRHLKSGKTV-MIRADELFPTASMIKVPIMLTAFQKIE +EGELDYHGEQTYRDSLLYAGEDILGSFKDGEIKLSKVIMLMITTSDNTASLWCQKLVGTG +TAINEWLQAHGFSQTRVNSRTPGREADREKFGWGQTTPREMAELLVMIREGRAVSPDASE +EMYRTLTRIYWN-GEALSQIPPFIQAASKQGAVNR-SRSEVVLVNAPSGD-YVFCVITKN +QEDEDNAGYVLLRNISRLLWEYf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces asterosporus TaxID=285570 RepID=A0A514JRM2_9ACTN +---ALARIRAAFSDAGVTGWLHALDIDSGAQL-DAGADQPVCTASVHKLCVLVTLHEQAA +AGLLDLTEQVECPPEGRTPGPTGTAAMLDAALSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTARLGLARTRAVHSFGDMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA +AVRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AQATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus aerius TaxID=200253 RepID=UPI000CCC22E7 +------------HGYAGEVGVLITDLAGRGLY-ALNSGRVFPAASTIKVPLLVRALQEAQ +AGRLDLRERVTVREEDRAGGSGILHEFGPGLPTWEDLLTLMIVVSDNTATNLVIDRL-GV +ECVNGWLDGLGLGGTRLVGKLERQNEAQRRGERNRTAARDQVNVLGRLARGELLDPAHTA +LALSILSRQQL-RDILGRHVPRSYRVASKSGELP-GVHHDVGLLFTP--RPLVVAVLSEG +GL--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Streptosporangium minutum TaxID=569862 RepID=A0A243RHS5_9ACTN +-----EALREAFGDADVEGFIHVRDVDGGAEI-GLGADEPVVLASVFKVPIVLEYARQAA +AGTLERTERLTVTAADKDGGIGTSGCADDVSLTLRDLAHFMMTMSDNAATDVLLRRV-GL +GNLHATLRELGLERTRLIGGCAELLGILDPERTTSGTPRETTTLLSKIWRDEAGPPEACA +EVRRIMGNQVW-PHRLSSGFGDEVKVSGKTGTLW-GVRNEAGVVEYPDGRRYAVAVFLRT +GSFRLPKADRVIGHAARVAIDH- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SAI-097 TaxID=2485145 RepID=UPI000F4C7234 +--AVAARLDAAFADAGVTGWLHAVDIDSGAQV-EAGADQPVCTASVHKLCVLVTLHELAA +AGELDLTERVECPPDGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL +DAVNGTTARLGLTRTRAVYGFAEMLDALDPARTNHSTPRDMTRLLGALWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Halomonas sp. MG34 TaxID=2600296 RepID=UPI001372D354 +-------------------QYSVLLTSGEGSL-AINEQQLRPAASLAKIPILIEACQQIE +SGRLHPDKLVYIEEEQFVEGSGIISYLTNSHYSYMNLIELMMIVSDNTAANVLLESL-GM +EAVNQTIEQLGAKNTVVQRKFMDTKAQ-QEGLENYTTALDMVTLLKAISEEDYISSKSRK +FMRSILAKQQF-TNKLANFLHPSVTIFHKTGELC-GIEHDAAILECKEE-RVYITVLSDH +LP-SNAEGQHTIAQIGKHAIDY- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus erythropolis TaxID=1833 RepID=A0A1Q4K9K9_RHOER +--SAQQEIAAVLAEAKTDAYVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA +AGALDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. KBW08 TaxID=2144188 RepID=A0A3N7BBW3_9NOCA +--SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWKDEAGPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Nonomuraea sp. SBT364 TaxID=1580530 RepID=UPI00066E378A +---------------GARGFVHARDIDGDAEF-GVDPDEPVVLASVFKIAVALEYARQAA +AGELSRTERLTVTAADKDGGIGTSGCADDVSLTLRDLAHFMLTMSDNAATDVLLRRV-GL +DRVHATLAGLGLRRTRLIGGCAELFAVRDPERTTSSTPRETTELLAAIWRDEAGPPEACA +EVRTIMGNQIW-PHRLAAGFGDEVIVSGKTGTLW-GVRNEAGVVEYPDGGRYAVAVFLRT +AKGRDPDADAAIGRAARLAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora shandongensis TaxID=418495 RepID=A0A1H3EP55_9PSEU +---VERRIREVLADAGAEGWVHAKPLNSEREI-DVGGDELVVTASVYKLPLLVALCRAFD +AGELDPRARVRIDPASCTPGPTGMSAFQDPVVSWRDLAASMIGVSDNAAADLILGEV-GL +DALADTLADLGLSRTRVVGGTADSHAAYDPSYASATTPREMTRLLELVWADAVASPEQCE +FIRRLLANQAW-QHRIRAGFPRGVRVAGKTGTIG-AVRNEVSVVEFDGETPVAVAVFTLA +ARADAPGVDAAIAECARIAV--- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9MFY3_9BACT +---LDGRVRAELLKFRGKVSLFAKNLDTGLSY-GIGADDRVCTASIIKVPIMVEAFARVA +EGRAKWSDEVILTNAKKVPGAGVLQEMSDGLLTLRDAVNLMIVVSDNTATNLVLDAL-TT +DGVNERMDSLGLKQTRALRKIEDGGERAAQDPANVSTPREMVTLLERLERGGVVNPTASK +EMIDLLKRQQS-HNGIGRTLNGIVEMASKPGALDH-LRSDVGIIYAKQGR-VAMAITCDD +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Nocardia yamanashiensis TaxID=209247 RepID=UPI000A07B2BE +----AQHISAVFADAGCTGWLHARRCDSPAEI-SVDGHARVVTASVYKLALFLAFCRDID +SGRLDPTTRLTVDPTTCTPPTGLAALRDPVTLSLRDLAASMMTVSDSAAADILLGEI-GL +PAIDSLLTGLGLTETRVIGGTADMHRAYDPAYTSATTPEEMTRLLHALWTGSALSPERTE +FAKSVMRQQVW-QHRIAAGFPSNVSVAGKTGTIGI-IRNEVAVVEFPGEFPVAVAVFTRA +ARADLPAVDAAIAEVARIAVT-- +>[subseq from] Putative beta-lactamase n=1 Tax=Synechococcus sp. RS9916 TaxID=221359 RepID=Q05XQ7_9SYNE +--TLSQRWRDLAAQADLKVSAFMLVLDDGRYA-ELGADTALPAASSIKTPILLAALERLD +AGDLHWNEPLTMTKPLVGGGAGWMAKPVGTRFPTYEVATEMIRISDNTATNLMIERAGGK +QAVNIRFNTLGLSATKINNWLPDLKGT------NTTSARDLARAIALVDTGEVLSTRSRD +LFREVMSTSRT-NRLLPGGLLKGYRVYNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG +PFN-DPRSTELIRDMAAAM---- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SYP-A7193 TaxID=2662065 RepID=A0A5P9WMJ9_9ACTN +--ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GVRADQPVCTASVHKLCVLVTLHELAA +AGALDLTEQVECPPDGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL +DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEAGPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. NJ-530 TaxID=2490853 RepID=A0A3G8ZUV1_9NOCA +--SAQQEIAAVLAEAKTDAYVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA +AGTLDPTEHATVTSEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia sp. NRRL S-836 TaxID=1519492 RepID=UPI0006AF387B +-------------AAGAEGFVHAREVANGPEV-AVGADDQVVLASVFKIPVAVAYAAEVA +AGRLDETERTRVTSRYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDVIFHRV-GQ +AAVDAVLAHLGLHRTRIMGCCEDLFAIVDPERTTSSTPREITTLLDAIWTDRAAAPQACA +QVRAIMAQQVW-PHRLSSGFPADVQVAAKTGTLPS-VRNEAGVVTYPDGRAYAVAVFTRA +DSPRQPAVDAVIGRAGRLAVDH- +>[subseq from] Putative Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces aurantiacus JA 4570 TaxID=1286094 RepID=S3ZPM0_9ACTN +------RLQETFAEAGVTGRLHALDIDSGAEI-SAGADQPVVTASVHKLCVLVTLYEHAA +AGRLDLTEQVECPVDGRTSGPTGLAAMLDPVVSLRDAAYLMMAVSDNTAAELLLRRV-GL +DAVNATTARLGLTRTRALHTFSEMFAALDPARTNHSTPRDMTRLLGALWRDEACTPEHGA +AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA +ARATLPPADAVIGTAARIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces varsoviensis TaxID=67373 RepID=UPI00099700E5 +----QRTIRGMFADAGVRGWLHVADLHRPAACvTIDPDEPVPIGSVYKAPLMVAFCRLAE +AGEIDPCRRVTLGPADRLPPTGISILRDPVTVSLRDLVVLMMTVSDNTAANAVLRLV-GT +AAVDEVCRALGMADTRVHGGVATTFAVYNPLSKASASPADMARLLRAIWTGRAASPESCA +FMREVMGRQAW-SHRLGSGFPDDVRVSGKTGTFGS-MRHEAGVIELPDGSAYTAVVFTQA +ARADLPRADAVIGAAARTAVE-- +>[subseq from] Uncharacterized protein n=2 Tax=Bacillus TaxID=1386 RepID=A0A264Z118_9BACI +------------SMYRGRVSYLFET--PEETI-EQGATNVYPSASTIKLLVAIEACRQID +SGVILAHQTIAVKQSDIVGGDGLLSVYPYSPATVKELLILMLILSDNTATNLLIKLL-GQ +ECIQGCIKDLGLKNTQLNRQMMDIQAS-AEGRDNVTTAADLLTCLKVLYRKDVLSEPSRK +LLKESLFNQRL-RDKLPSMLNEKCFILNKPGHLH-GITHDCGVLFTHHKR-CYAVVLIDG +LK-HNEYGRRLIADLGQVIS--- +>[subseq from] Serine hydrolase n=1 Tax=Spirosoma sp. HMF3257 TaxID=2183553 RepID=A0A327NIF9_9BACT +-kALERKLRAVLTNFRGNSGVYVRNLRTGKTV-SINADTLFPTASMVKIPIQCGLFDKIH +QGAIQYDQELTYKDSLHYDDGIVGSLKDGAKITLSKVVMLMETVSDNTGSLWCQALAGGG +TAINAWLETNGFHQTRVNSRTPGREANRTQYGWGQTTPREMAELLTYIRQGHAISPDASE +EMYRNLGRQYWD-NDGLSQVPPGVKVASKNGAVNQ-SRSEVVFVHAPHGE-YVYCIMTKN +QKDETNEGYTLLRSVAATVWHHf +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces radiopugnans TaxID=403935 RepID=A0A1H9BAR1_9ACTN +-------------ALGARVRLHARCVDCGRQT-GTGADEPVVLASVVKVPLVLEFARQAA +YGQLDPAERVLVRQADRLGGTGTAGCRDDVEMSLRDLAFLALSVSDNTAADVLFRRV-GT +DTVALLARELGLEGTRIAGSPRDLLETSDPRRTNSGTARDMTRLLALIWTDRAGPPRACA +EVRELMARQVS-WHRLAAAFPEEVAVAAKSGTLP-GVRNEIGVVSPPGGGRYAVAVFTET +ESRRRPDLDAAIGAAGRAAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium 41-5 TaxID=1895836 RepID=A0A1Q3K2Z8_9SPHI +-qKLEKKINQAIKGFNGDIGIFVKDLKSGKTV-AINADTIFPTASIVKVPILMGITDKIM +KGQYAYDSTVAYDSSYLYRGEDILGEFKDSGIRIKKLIMLMLTTSDNTASLWLQALSGTG +TRINQILDSLGYKSTRVNSRTPGREVNRSRYGWGQTTPREIAGIIESIYRTKIFTPYYCD +IMMRSLGRNYWDEDEGISVIPPYIEVFSKNGCVNQ-TRNEVMLVNAPNR-PYILSIFTKN +NKRHDNEAWALTRKISTLLWDYf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces aurantiacus TaxID=47760 RepID=UPI000D132C7D +-------LQETFAEAGVTGRLHALDIDSGAEI-SAGADQPVVTASVHKLCVLVTLYEHAA +AGRLDLTEQVECPVDGRTSGPTGLAAMLDPVVSLRDAAYLMMAVSDNTAAELLLRRV-GL +DAVNATTARLGLTRTRALHTFSEMFAALDPARTNHSTPRDMTRLLGALWRDEACTPEHGA +AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA +ARATLPPADAVIGTAARIAVE-- +>[subseq from] Serine hydrolase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2A8VWX7_BACME +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKLEELLTLMIIVSDNTATNELISLV-GF +EKINECAKDLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLKMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Beta-lactamase class A n=2 Tax=Chryseolinea serpens TaxID=947013 RepID=A0A1M5UC68_9BACT +---LTGKLQETLQGFKGVAGVYVRNLRTGKTV-TINADTLFPTASMIKIPITIGMFDRID +RGEIDYHSTLTYKDSLLYEGEDILGSFKNGEIALSKVMMLMITTSDNTASLWCQSLAGTG +TAINAWLEKNGFENTRVNSRTPGREANRTRYGWGQTTPREMAELVTRIREGKVISPRASE +RIYRNMVRIYW-DSEALSQIPPYVQAASKQGAVDQ-SRSEVVLVNAPHGD-YVFCVITKK +QETPANEGYVLLRKVSRLLWNYf +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI0007D8B3A8 +--ELEKRLSAIIGQAEGTWGVVVEEQGKGTRF-VHVPDELFIAESVIKVPIMAAVFAASE +QGHFRMDDQLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK +DQIDQTMIDLGMHQSCYSRKLMIYPLD--IAENNKITAGDVASMLGHLATGSFLSQRACK +EMIAIMKKQQV-RNGLPSQLPPGWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD +VT--AQSALNTLGLLGRAVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Rufibacter immobilis TaxID=1348778 RepID=A0A3M9MYY5_9BACT +-rQLTQKLLALTKDFKGDVGIYVRHLKSGKTV-AINADTLFPTASMIKVPIMVGVFDKME +RGELNPKTILRYRDSLYYAGEDIVGNFKDSSVALGKIQMLSITTSDNTASLWLQQLAGTG +TAINIWLEKNGFTHTRMNSRTPGRRSNWEKYGWGQTTPREMATLVTMIREGQAVSATASE +RMYRNLGRIYV-DDIALSQIPPNVHTASKQGAVNR-SRSEVVLVNAPHGD-YVFCIITKN +QQDENNAGYALIRAVSKTLWQHf +>[subseq from] serine hydrolase n=1 Tax=Bacillus horikoshii TaxID=79883 RepID=UPI0011E973A4 +---LKERVQAVVDSTAGHVSYVIDD-GNGQRL-GKDADVTKKAASLIKIPIMMAVFKQVE +AGILSLSDRYSIDNRNIVSGAGVIQFMESDTFTLGELLTLMIIVSDNIATNKVIDII-GW +NVVNDFCREQGLTNTKLERKMMDFKAA-DVGLENRTSALEMIECLKYLHIEDVFSDESRQ +KMLRILGGQQL-LDKLPFYMDELVGIANKTGELP-GVEHDCGIVTYKGEK-LFVAVLIDD +LV-DNSIGKRAIQEIGKVVEE-- +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. WMMB499 TaxID=2650775 RepID=A0A5J6UL25_9ACTN +--------------AGVTGHCHAVDVDTGRDV-GVRAGEPVVLASVFKVPLLVAFHRRVA +AGTLDPTERATLPAADRTSPTGVSALLDDVRMSLRDLATLMITVSDNAAADFLLDRV-GL +AAVNAAAADLGLPGTFVAGGGREMLDVRPLDPTSRSTPREMTRLLSLIWRDEAAPPAQCA +AMRRMFGLQVW-PHRLSSGFPEDVVVSGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRT +PVAVHPQGDAVIGTAARIAVEH- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000E1A3246 +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILTLTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIMVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVKKGIDNYTCASDVVKCLREIYEGNLLQKSSSE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-PYYAVVLIDG +LS-DNEQGRRLIADIGYLL---- +>[subseq from] serine hydrolase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=UPI000762164E +---LENKIREIVIRCTGRVSVAVELP--SHSF-HINGDSTYSAASLIKIPILLEGFRQAQ +EGKISLSDRVTIPKEGRVGGAGVLVSLSDHLLTVEDLLTLMIIVSDNTASNLLIERL-GS +IAIQDLCDTLQLKQTMLRRKLMDFEA-VEQGLNNYTSALDIISCLKVLDIGTEYSPTSRK +KMLHILHQQQF-DTKLPSRMDRGVYIANKTGELP-GVEHDSAIIKFREKT-AYIAVLIDE +LGQN-EPGKDTIAQIGKLMS--- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 203-3 TaxID=2559918 RepID=UPI0010F7BD68 +-------------------AV-AIQTTTGQTY--YWHNRQQKAASVIKLFILATVYQQVV +DKTLRLDTTYTLKARDKVGGTGNLQAAVGTPVTYRALVKAMMTVSDNTATNILIRAVGGR +TVVNREIARLGATKTRLNRLMMDQ-TALAAGRDNVTSVGDLSRVLMRLWHHRLISPAADT +AMLNLMAANTN-HQKLPRLVSSQLKVYNKTGEFDYGVENDAAILAKG-RRAIVVVALSQG +GT--LAQQLPAMNQLGHQVT--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-244 TaxID=1463897 RepID=UPI0004C063BB +-----RRIAAAFAEAGVSGRLHAVDIDSGTEI-DAGADQPVVTASVHKLCLLVALHQHAA +AGRLDLTEQVECPPADRTAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL +DGVNEATARLGLTRTRAVHTFRSLFAALDPARSNRSTPRDMTRLLAAVWRDEACTPEHGA +AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA +ANATLPAADAVIGATARIAVD-- +>[subseq from] Amidohydro_3 domain-containing protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7VHR0_9BACT +------SVQALKRKHKERLGIALYDSETRVQW-SYNGDAFFHAASTMKLAVLVGVFRQVF +RKELGLETPVRVRNRSLVGGLPFSVARLGKTMNVKDLAYRMITTSSNFATNLLIDLV-TV +GVIHKALDELRVEGIEVLRGVDDQK-AFAAGKNNMVTADGLLKLLRLISDGRVYSPEISG +QLLEILLDQRV-KRGIPAGLPGGARVAHKTGHIST-VHHDAGIVYIGQRRPYAVVILTQS +PA--GAGGDAAVADASRQIYN-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3C0XGD1_9CHLR +-----------ATDLDGSAGLIVLDAGGTVLY-ERAADESYAAASVIKIPILMTVYADAA +EGRLSLDERIGVGE--HMPGTGVLGHVRGVALTIRDHATLMTIVSDNTSTNRLMERV-SV +ERIAERMREWGCVRTELRRKMFDFEAA-NRGLDNVASPREVAGLLLRLVRGELVDRATSD +AVLAVLEATQD-DALIRRYLPARTKVAHKTGSLDK-VRNDAAVIWAE--RPVVTVGFVNG +V---------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Desulfocucumis palustris TaxID=1898651 RepID=A0A2L2XGC0_9FIRM +-qGLQNRLEQMLGREKGTYGVLVMDIQSGRVC-ALNPLEPFHAASTFKLPMNIYLFKKIA +SGETDPGQKLVYRESHYEGGTGKLQYSPGTSYTIETLSQYSIIYSDNVATNVLLSFL-GK +KNVKDFMRQSGGLVV--------------DDSKNLTCPRDMALYMRELLEFAGQSPEQAN +RLIDYLENTVF-NERIPALLPKSVKIAHKIGNWPTATYNDVGYVRHPVN-PYIISIFSKN +TP-GAGRAYDVISRISKAVYDY- +>[subseq from] serine hydrolase n=1 Tax=Bacillus testis TaxID=1622072 RepID=UPI00067E7379 +-eQLKAELSKALAGFQGSIAYAIYD--GDGCI-AMNAGQRMKAASTIKLPLLLMAFRLYE +QGRLDIHREIPFTDLDIVPGSGVLQSMKQRSIRLEDALSLMITVSDNTATNLVIDAI-GL +DRCKDGFRDIGLKTASLQRKMMDYEGR-EAGKENWISAEDLIVSLKRIQNEGSFSEESRK +AMREMLINQQF-RDKLPYLIDENIAVANKTGEIE-GVENDCAIFFYKNHV-LYAAVLCGN +LKK-EGEGQRIIRHIGDK----- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. Tu 2975 TaxID=2676871 RepID=UPI00135A2782 +----EERLRAVFAGAGAEGVLHAVDIDGPGEA-GYCADEPVVVASVFKVLLVLEFARQSA +AGQLDPRERVRVTSERRLGGWGTGGCLDDVELSLRDLAHFAMAVSDNTAADLLLERV-GP +DTVAMLAKELGLVNTRIVGGPRQVLEVYDPARTNASTPREMTRLLRMVWRDEAGPPEACA +RVRDLMCRQVF-RHRLAAGFGDGVRVAAKTGTLP-GLHNEVGVAEFPDGGRYAVAVFART +PGANHTETDVAIGAAARTAVD-- +>[subseq from] serine hydrolase n=1 Tax=Saccharopolyspora rectivirgula TaxID=28042 RepID=UPI0003FD27FD +------------SRFPGRVCLAAWHLEEREPV-LVNAETVVHAASTIKTLVMITALQQVQ +AGRLALDAEVPLPAE-RPGGAGVLAELTSVHLSLADLLRLMIVISDNTAANAVIDVV-GF +PAIRRCAEQLGCTATRVERRLMEVSA--PG--RIETTALDQARVFDALATGRALTTELTG +FALDVLRRQQV-RDRLPALLPREAGCWHKTGEIS-GVRHDVGLIGGS-RPQAVVAVLVDQ +LTDERSTADELIARIGRAAFD-- +>[subseq from] zinc_ribbon_2 domain-containing protein n=2 Tax=Enterococcus pallens TaxID=160454 RepID=R2QQI0_9ENTE +---------------DGNFSVLLAPIEDGPTF-TMEEKNMRRAASVIKLFIMAAVYEQVD +QKRLALNQEYTLLSQDIVGGTGVLQDYPIGSLTINQLLAHMMVDSDNTAGNILVEQLGGL +SELNNYLREQNFSGTVMNRLFLDTE-ALEAGIDNYTSAEDVARLLQNVYQQKQVSPVHDL +AMLELLNQNKN-HRKLPAQIGPEVNIYNKTGEYDYGIENDACIFEKDGN-AYVLVVLSED +GNSS--EQLVAMNRLGKEFYETf +>[subseq from] Serine hydrolase n=1 Tax=Bryobacterales bacterium TaxID=2026791 RepID=A0A3D1B169_9BACT +-qDLDRRINSEVDNFNGAVSLFAKNLNTGGTF-EIAGQRRVRTASTIKLAVMAAAFTEVS +RGHAAWTDRSTITEAGKISGSGVLMEFSEGVLPLIDLLRLMIVVSDNTATNLVLDHI-AP +DVVNAEMQQLGLIQTRCLRKVLNNHDENKAFGLGVSTPREMVTLMEKLYRGEVVSPRASA +EMLAILKRQQH-HSGIGRTLR-ETTIASKSGALDH-LRSDVAIVYAKGG-PIAMAITCDD +IPE-------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces calvus TaxID=67282 RepID=UPI0011520B6A +----LARIHAAFSDAGVTGWLHALDIDSGAQL-DAGADQPVCTASVHKLCVLVTLHEQAA +AGLLDLTEQVECPPEGRTPGPTGTAAMLDAALSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTARLGLARTRAVHSFGDMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA +AVRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AQATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Rufibacter ruber TaxID=1783499 RepID=UPI00082CA865 +-kKLTQKLEALANGFQGDVGIYVRHLKTGKTV-AINADTLFPTASMIKIPIMVGMFDKME +RGEIDPKTVLRYRDSLYYAGEDIVGNFKDSSVALSKVQMLSITTSDNTGSLWLQQLAGGG +EAINAWLEKNGFQHTRMNSRTPGRRPNWVNYGWGQTTPREMATLVTMIRDGKVVSPAASE +RMYRNLGRIYY-DREALSQIPPYVHTASKSGAVNQ-SKSEVVLVNAPHGD-YVFCIITKN +QQQDDNAGYVLIRKVSNTIWNHf +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus gobiensis TaxID=1441095 RepID=A0A0M4FMQ0_9BACI +-------------------SLCIC--TDDGEI-NINDNQRMAAASVIKLPILLEGFRQSN +VNLLNLETKIEVTDQDRVGGSGVLKSFRGVELSVRNLMALMITVSDNTASNLLIDLI-GM +KNIQSFVNSVGCSNSFLRRHFMDTQA-MKAGIENETTARDMVGCLKLIAEKNIFTELNRE +EMLSMLSGQQF-HKLINQPVGPNIELYNKTGDLP-GIDHDVAILKHKER--LVYIAMLTK +GWKDRETGLKIIKRIGQLMMR-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces radiopugnans TaxID=403935 RepID=UPI000B883120 +--------------LGARVRLHARCVDCGRQT-GTGADEPVVLASVVKVPLVLEFARQAA +YGQLDPAERVLVRQADRLGGTGTAGCRDDVEMSLRDLAFLALSVSDNTAADVLFRRV-GT +DTVALLARELGLEGTRIAGSPRDLLETSDPRRTNSGTARDMTRLLALIWTDRAGPPRACA +EVRELMARQVS-WHRLAAAFPEEVAVAAKSGTLP-GVRNEIGVVSPPGGGRYAVAVFTET +ESRRRPDLDAAIGAAGRAAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Nocardia donostiensis TaxID=1538463 RepID=A0A1V2TEU3_9NOCA +-------IRDVFADAGCTGWLHARRCDSADEV-SVGGGERVVTASVYKLALFIAFCRCVD +AGLIDPAEPLTVRPAECTPPTGIATLHDPVTLSRRDLATSMMTVSDNAAADVLLGEV-GL +RAIEDLLTGLGLTQTRIVGGTADIHRAYDPAYTSATTPEEMTRLLREVWSGAVLSPGQTE +FVRTVMRNQIW-PHRIASAFPRGVSVAGKTGTVGI-IRNEVAVVEFPEEYPVAVAVFTRA +ARADLPIVDAAIAETARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. dk17 TaxID=2599295 RepID=A0A563U7U8_9SPHI +--KLTTQLQKAVSGFNGQVGVYVQNLKTGKVA-AINADTLFPTASMIKVSILAGVMDKIE +KGELQYNQKLKYRDSLLYAGEDILGSFKDGDIYLSKVAMLMITMSDNTASLWLQKLA-DG +KNINNWLEQNGFKYMRINSRVEGREAMRPIYGWGVTTPREMCKLFTMIHDGTAVSPAASE +RMYRTMSHIYW-DQNALAQIPPYIQTISKQGAVD-ASRSETVLVNAPHGD-YVFSVITKN +NKTADNEASTLIRKISALLWHYy +>[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. AG162 TaxID=2572910 RepID=A0A542Q6C2_9BACL +--ELEKRLSAIIGQAEGTWGVVVEEQGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE +QGHFRLDDQLVLRQEDLVGGSGILYALSPGLLAIRDLVTLMIIQSDNTATNMLIDLV-GK +AQIEQTMIDLGMRQSYYSRKLMIYP--IDITENNKITAGDIASMLGQIATGSYLSQRACK +EMIAIMKKQQV-RNGLPSQLPNQWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD +VT--AQSALNTLGLLGRAVYDY- +>[subseq from] Serine hydrolase n=2 Tax=Deinococcus sp. S9 TaxID=2545754 RepID=A0A4R5G8N3_9DEIO +-------------GYVGEMGVLITDLAGRELY-ALNPNRVFPAASTIKVPLLLLALSEAQ +AGRLDLSGRVTLRAEDRVPGAGVLHELMPGLPTWQDLLTLMIVVSDNTATNLVIERL-GL +DRVNDWLDERGLSGTRLVGPLERQNAAQRRGERNRTTARDQVALLGALVRGELLDRRHTG +LALSILERQQL-REILGRHVPCDYRVASKSGELR-GIHHDVGVLFTP--RPLIAAVLSQG +GLDPR------------------ +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3L7YAP9_9CHLR +------------------ASIAVVHLETGASA-TVNGDRIAVPASLYKVGVLVEAFRQIE +AGLLRLDETLRLLPIDWAPGAGILQGRIGTQVTITDALRLMIGISDNTAAHAIVRRI-GV +DRVNANNQRLGLSNTRYYI----------DNRPDTTTAADMARLLSLLATGRLAGVEATG +QMLDLLQQVQP-AAWLPRGVPPTIAVAHKSGQLD-AVRNDAGIVFGPTGR-YVVVVLTDN +RP-NAMKGENAIVQVARSVHAYf +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2E7BNN8_9BACT +-dKFQQDLEALVEDFNGVAGLHIMDLTDRTRF-AISDGLVFPQASAIKIPILLELFRRAD +TEPGLLAKRVDLTDAVRTAGSGVLQILTDGGLSLEDYAIYMIVYSDNTATNVLIDEL-GM +EEINALSTSLGARRTRLQRKMIRPEESVLG-NENLSTPRDAALIMEKIATCDLLSQASCK +RVRDILELYKGG--PIRAPIPRSVPIAFKPGGIV-GVATVWGLVNLPDR-PYIVAVMSNY +GG----NGSAMIEAVSAVAYSYf +>[subseq from] Beta-lactamase class A n=1 Tax=Halorubrum cibi TaxID=413815 RepID=A0A521BWE8_9EURY +--DLAEAIDAIAERFDGHLGVFLGVPRESNAFhRRNADETFVAASTIKLPILYALYEEYD +GRLDDLAEPRSIAPENRVGGSGMFHLLEDPTPSLEDLARAMIAISDNAATNQLIDEV-GA +ERVEAAASRLGMNDTRLRRKMMSTLEQPEGEPANATTPADCARFFADLIHETTLSPAAYD +RLRVPLDEQKD-TSLFARYLPYGTPIAHKTGGLPT-AALDAGIVRADDGPALVFAAFATR +AE-NGGDAGDAVAAVGDAAFERf +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura bangladeshensis TaxID=453573 RepID=A0A4R4P0N4_9ACTN +-------IEAEFRAAGVTGFLHVADMDTGREV-AVRAGEPVVLASVFKVPLLVAFHRRAA +AGLLDPAEQVTLAPGDRTAPTGVSALLDEVRMSLRDLTCLMITVSDNAAADAVLDRV-GR +DAVNAAAADLGLRATVVEVNGRELHEALDPARTSRSTPRDMTRLLSMIWRDEAAPPDHCA +AMRRLLGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-VRNEVGAVEYPDGARYAVAVFTRS +TLAVLPRADAVIGTAARLAVE-- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A641W8R3_BACOV +------------------------------------------------------------ +-------------------WSPLRERFPQGGFSLKGLLGVTVQESDNNTCDLLFGLIGGP +QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILARGTQN +FLWGIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD +SKDSESACDRVIASMARWLCMEw +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. HBUAS56010 TaxID=2571127 RepID=UPI00117774B6 +---------KRLEQLPGKIGFYYENLNTEDVI-FYKDQEPFLAASVIKLFIMAVAFEQLE +RGDYNCKMLFSIKQKDCVPCGALTYLHEGIEVTVMDLITLMIIFSDNTATNVLIEHM-GI +EEINTAIKRFGFEKTVLRRKMFDLEKA-RNGIENYITVGEVGKLLKIMYAGTLISKQASE +KMLSIMKNQQL-TGKIPFYLKHMPEIAHKTGEDM-GISHDVGIIYGKN--PF-IVCFCGN +ET-DTPRFERVMADISLELYK-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces coelicoflavus TaxID=285562 RepID=UPI0013C1F072 +--ATAARLDAAFADAGVTGWLHAVDVDSGAQV-GVRADQPVCTASVHKLCVLVTLHELAA +AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL +DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEAGPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Rubrivirga marina TaxID=1196024 RepID=A0A271J886_9BACT +-------------------AVAVRDLETGEAA-TVDGDRPFHAASTMKVAVLAALLAAVA +DERHHLDDRLHVRNRFRSAGSPFRFAKRGRTMPLGTLAEHMIQTSSNLATNLLVDLL-GV +EAIREATARWGGAGVEVVRGVED-EAAYEAGIVNTATAYGLVGLFVGLEEGAGLPDEVRQ +FGLDVLFGQEF-ASGIPAGVPEGSRFAHKTGSIST-VQHDAGLVYLPDRRPYAVAILTEW +EADATNGRRETVASLSRAVYDH- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A3D2FNG6_9BACT +-eKLETDILELLQGFNGDVGVYVRHLPSNTEV-GVNENEIFPTASMIKVPILVKIFDKIE +GGALTMDSVVIYKKASINYGDDALARFNDGEITISKLLTYMITFSDNHASLWLQDMAGGG +VTINGWLKNKGFIHTRVNSRTPDREAEYEIYGWGQTTPREMAELLVLIREGRAVSPAASN +DMYRHLTRIYW-DDEALSQIPPTVQVASKQGAVSQ-SRSEVVLVNAPSGD-YVFCIITKN +QTDTDNEGFILIRNISKLLWQHf +>[subseq from] serine hydrolase n=1 Tax=Bryobacterales bacterium KBS 96 TaxID=639034 RepID=UPI00037AA8B9 +--KLSQRIAYKIAGFPGKVSLFAENLQTGASY-GLLANEPVRTASTIKLAVMIECFAETG +EGKLKWTEPLAVSAENKVSGSGVLTEFSDGVLPVRDVMHLMIVVSDNTAANMLLDRV-TG +NAVNARMAGLGLRQTRIMRKILGDAGAKPENRKGRSSPREMVEILEKLYHGDLISQNASA +EMLAVMKRQQD-HSGIGRDLN-DVTIASKSGALDR-LRSDVGIVYSERG-PIAMAITVDD +IPTADNPGSLLISAVSDI----- +>[subseq from] Uncharacterized protein n=1 Tax=Oceanobacillus iheyensis TaxID=182710 RepID=A0A2P1WPA6_9BACI +-------------------QYSVLLTSGEGSL-AINEQQLRPAASLAKIPILIEACQQIE +SGRLHPDKLVYIEEEQFVGGSGIISYLTNSHYSYMNLIELMMIVSDNTAANVLLESL-GM +EAVNQTIEQLGAKNTVVQRKFMDTKAQ-QEGLENYTTALDMVTLLKAISEEDYISSKSRK +FMRSILAKQQF-TNKLANFLHPSVTIFHKTGELC-GIEHDAAILECKEE-RVYITVLSDH +LP-SNAEGQHTIAQIGKHAIDY- +>[subseq from] Serine hydrolase n=1 Tax=Cyanobium sp. TaxID=2164130 RepID=A0A2W6Z3B2_9CYAN +--ALSQRWKALAAQKDLKVGGYLLVLDDGRFA-QLDPDVPLPAASAIKTPILLAGLEDLD +AGKLRWNDPLPLTKEVIGGGAGWMASRPIGTFPFSEAATEMIRVSDNTATNLLIRRLGGK +LALNARFQALGLDATVLNNWLPDLEGT------NTTSPRDLARSIALVDTGEKLSPRGRD +HFRSILATSRT-NTLLPLGLLKGIAVLNKTGDIGI-AYADAGLIELPNGQRAVAAFMVKG +PFND-PRSAELIRAMAAAAS--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02400 TaxID=1703944 RepID=A0A1Q5M873_9ACTN +----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVPTASVHKLCVLVTLHEQAA +AGLLDLTEQVECPPAGRTTPTGVAAMLDAVRMSLRDLAFLMMTVSDNAAADLLLRRV-GL +DAVNATTARLGLTRTLAVHSFGEMLAALDPARTNRSTPRDMTRLLAAVWRDEACTPEHGA +AVRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARTAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7UAW0_9BACT +------SIQAVKRKHKERLGIALYDSETRMQW-SYNGDAFFHAASTMKLAVLVGVFRQVF +RKELELGAPVHVRNRDLDRASPEVAGRLGKTMSVKDLAYQMITTSSNLATNLLIDLV-TI +GVIQKALDELRVQGIEVLRGVDDEK-AFAAGKNNMVTAHGLLRLLRLISDGRVYSPEISA +ELLEILLDQRH-KSGIPAGLPGGAHVAHKTGNIST-VHHDAGIVYIGKRRPYAAVILTQS +AA--GVGSNTAVAEVSRQIYS-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptosporangium canum TaxID=324952 RepID=A0A1I4DBK2_9ACTN +-----EALREAFGDADVEGFIHVRDVDGGAEI-GLGADEPVVLASVFKVPIVLEYARQAA +AGTLERTERLTVTAADKDGGIGTSGCADDVSLTLRDLAHFMMTMSDNAATDVLLRRV-GL +GNLHATLRELGLERTRLIGGCAELLGVMDPERTTSGTPREITTLLSKIWRDEAGPPEACA +EVRRIMGSQIW-PHRLSSGFGDEVKVSGKTGTLW-GVRNEAGVVEYPDGRRYAVAVFLRT +GSLRLPKADRVIGHAARVAIDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga skermanii TaxID=331697 RepID=A0A327QMQ9_9BACT +-rKLTEQLQPLLRSFQGRAGIYVENLSTGKIV-QINADTVFPTASMVKIPIMVGIFQKIA +HDSLTYHQALVYRDSLLYEGEDILGSFKDSEIQLSKVMMLMLTMSDNTASLWLQSLAGGG +QSINNWLGEHGYTYTRVNSRTPGRQANRELYGWGQTTPREMATLMKSIYQGKVINKTASE +RMYRNLTRNFW-DTEGAVMVPANVRTATKNGMVD-ASRSEVILVNAPHGD-YVYCLQTKN +NTERNNEAWVLMRQVAALLWKYy +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus sp. Leaf182 TaxID=1736290 RepID=UPI0006FFF24F +--ELEKRLSTIIGQAEGTWGVVVEEQGKGIRF-EHVPDELFIAESVIKVPIMAAVFAASE +QGHFRLDDQLVLRQEDLVGGSGILHALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK +AQIDQTMIDLGMRQSCYSRKLMIYP--LDVTENNTITAGNVASMLGHLATGSYLSERACK +EMIAIMKKQQV-RNGLPSQLPPAWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKE +VT--AQSALNTLGLLGRAVYDY- +>[subseq from] serine hydrolase n=1 Tax=Streptosporangium canum TaxID=324952 RepID=UPI000AC9A41A +-----EALREAFGDADVEGFIHVRDVDGGAEI-GLGADEPVVLASVFKVPIVLEYARQAA +AGTLERTERLTVTAADKDGGIGTSGCADDVSLTLRDLAHFMMTMSDNAATDVLLRRV-GL +GNLHATLRELGLERTRLIGGCAELLGVMDPERTTSGTPREITTLLSKIWRDEAGPPEACA +EVRRIMGSQIW-PHRLSSGFGDEVKVSGKTGTLW-GVRNEAGVVEYPDGRRYAVAVFLRT +GSLRLPKADRVIGHAARVAIDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Pedobacter ruber TaxID=990371 RepID=A0A1G9TGI2_9SPHI +-kRLTKELHKLVKDFKGDAGIYVQNLRTGRVA-AINADTIFPTASMIKVPIMCGVFDKIE +KKELSYHQSLTYRDSLLYAGEDILGSFKDGEIQLSKVQMLSITTSDNTASLWLQKLV-GS +EHINKWLAENGFEHTRLNSRTAGRQAYQKLYGWGQTTPREMALLVKKIREGQAVSPAASE +RMYRNMIRIYW-DAEALSEIPPYIQAASKQGAVNR-ARSEVVLVNAPHGD-YVFCIATKN +QETPDNEGYRLIRNLSKLLWNYy +>[subseq from] Serine hydrolase n=1 Tax=Bacillus horikoshii TaxID=79883 RepID=A0A1Y0CPI7_9BACI +---LKERVQAVVDSTAGHVSYVIED-GGGQRL-DKDAYVTKKAASLIKIPIMMAAFKQVE +AGILSLSDRYSIDTRNIVSGAGVIQFMDGDTFTLGELLTLMIIVSDNTATNKVIDII-GW +NGVNDFCREQGLTNTKLERKMMDFKAT-AAGIENRTSALEMIECLKYLHIEDVFSDESRQ +KMLRILGGQQL-LDKLPFYMDELVGIANKTGELP-GVEHDCGIVTYKGEK-LFVAVLIDD +LV-DNSIGKRAIQEIGKVVEE-- +>[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora rectivirgula TaxID=28042 RepID=A0A073B8H8_9PSEU +------------SRFPGRVCLAAWHLEEREPV-LVNAETVVHAASTIKTLVMITALQQVQ +AGRLALDAEVPLPAE-RPGGAGVLAELTSVHLSLADLLRLMIVISDNTAANAVIDVV-GF +PAIRRCAEQLGCTATRVERRLMEVSA--PG--RIETTALDQARVFDALATGRALTTELTG +FALDVLRRQQV-RDRLPALLPREAGCWHKTGEIS-GVRHDVGLIGGS-RPQAVVAVLVDQ +LTDERSTADELIARIGRAAFD-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus qingshengii TaxID=334542 RepID=UPI0007E5A6E3 +---AQQEIAAVLAEAKTDAYVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas sp. SGT-18 TaxID=2493087 RepID=UPI000F629538 +------------------------------------------------------------ +----------------------------------------------------------GE +PRLQALADALGVPRAELDTTLEQVFEDYYARGLNSATLPAYGRLLERLASGELLSPRSTA +LLLGHMRAISTGSRRIQAGLPAGADFAQKTGTQQQ-RACNVGLLDPGGRDGATVVVACAE +HFGELEQAEQAFQALGRALA--- +>[subseq from] serine hydrolase n=1 Tax=Microtetraspora malaysiensis TaxID=161358 RepID=UPI0008311EE1 +-----KQLEQIFRTAGVTGWLHAVDIDTGREV-GLGADEPVVLASVFKVPLLVAFYRQAE +RGLIDPAERVTVSPEGRPGGTGVSAMLDEVTASLRDLAYLTISVSDNASADTLLARV-GL +GEVNATLADLGLPHTWVEHSCADLFTVLDPARTSRSTCRDMTRLLGMIWRDEAAGPASCA +AVRRLMGLQVW-PHRLASGFPDDVAVSGKTGTLPT-VRNEVGVIEYPDGGRYAIAVFTRS +IGQNQPRADAAIGTAARVAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. TMED19 TaxID=1986596 RepID=A0A1Z8N772_9SYNE +-kALSTKLAQLAAQKDLKIGAFALVLDDGSYA-QFNPDLVLPAASSIKTPILLVTLEALD +AGKLKLDELLSLNKTIVGGGSGWMGGQPGSQFTVLEVATEMIRVSDNTATNLLIQRLGGK +TALNARFQELGLEGTVINNWLPDLEGT------NTTTARDQARSIALVETAEVLSPRSRD +LFRQTLGTSRT-DTLIPRGWLQGVRAYNKTGDIGI-AYVDSALIELPDGRRAVASYMVRG +PFN-SPRSTNMIRALSGATAAAf +>[subseq from] serine hydrolase n=1 Tax=Lacrimispora amygdalina TaxID=253257 RepID=UPI000BE322CB +-----EVITRKLNQLSGKISFLYENLETGEHI-GYREDQPQMAASVIKLFVMAFAFHQFD +TGKLMKDFSLSIHKKDCVPCGALTYLHEEIRVTALDLVTLMIIFSDNTATNVLIDLF-GI +EEINQYIASLGFERTCLNRKMFDLEKS-RQGIQNYITASEAGRLLKMMHRGELVSDTASR +QMISILKNQQL-RSKIPFYLQEKPEIAHKTGEDR-GITHDVGIVYGK--VPLLLCFCGNE +T--DTPAFERIMGELS------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CB02400 TaxID=1703944 RepID=UPI000A849B81 +----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVPTASVHKLCVLVTLHEQAA +AGLLDLTEQVECPPAGRTTPTGVAAMLDAVRMSLRDLAFLMMTVSDNAAADLLLRRV-GL +DAVNATTARLGLTRTLAVHSFGEMLAALDPARTNRSTPRDMTRLLAAVWRDEACTPEHGA +AVRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARTAVD-- +>[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. AcH 505 TaxID=352211 RepID=A0A0C2ACV5_9ACTN +--DAQRAIRGMFADAGVRGWLHVAELRRPTACvTVDPDEPVPVGSVYKLPLMAAFCRLAE +TGGLDPRQPVTLGADDRMPGSTGLSILRDPIVSLRDLVVLMMSVSDNTAANAVLRHV-GP +AAVDALCQELGLPDTHILGGVATTFEVYNPLSKASSTPSDMARLLRAIWTDDAASAESCA +WMRETMGRQAW-SHRLASGFPDDVTVSGKTGTFGT-MRHEAGVVELPDGAVYTAVVFTQA +ARADLPRADAVIGTAARAAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. K2S05-167 TaxID=2320857 RepID=A0A418V7K6_9DEIO +------------RGFAGEVGLLVASLEGEVLY-RHAEDRVFPAASTIKVPLLIAALQRAQ +AGDLELNGRVMMQDTDRVPGAGVLHELAGGLLTWRDVLTLMIVVSDNTATNLVIEQL-GL +DPSNAWLQARGLRETRLVGKEHLRNEAQRRGERNVTSARDQAALLLGLVRGDLLDGVHTR +LALEILKRQQL-RDIIGRRVPRDYAVASKSGELS-GVHHDVGVLYTP--RPLVVALLSQG +GQDPRE----------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. SLBN-192 TaxID=1119093 RepID=A0A542TVL8_9ACTN +----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA +AGVLDLTEQVECSPRDRTSPTGVAAMLDGARLSLRDLAYLMMSVSDNAAADLLLNRV-GL +DAVNRTTARLGLARTLAVHTFGELLAALDPARTNRSTPRDMTRLLAAVWRDEACTPEHGA +AIRRVLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT +ARTSLPAADAVIGTAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia paucivorans TaxID=114259 RepID=UPI000308390F +---VEDRIRAVFADAGCTGWLHARRCDSAAEI-SIAGYDRVVTASTYKLMVLVAFCHAVD +LGRIDPLAPITVVPSECTPPTGISALHDPVTMSRRDLVTSMMTVSDNAAADILLDEV-GP +GAVEELLDRVGLTRTRIIGGTADIQRAYDPAFTSSSTPEEMTRLLQAIWTGTVVSVEQTE +FIRTVMRKQVW-PHRIASAFPRGVTVAGKTGTIGV-IRNEVAVVEFPGEYPVAVGVFTRA +ARADLPVVDAAIAEAAWIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Solimonas sp. K1W22B-7 TaxID=2303331 RepID=A0A346N395_9GAMM +---------ALFQAAGVDGWLHALDLADGREI-GYHADEPVVAASVFKIPVMVELCRQAD +AGQIDLSEPVSVPLAGRAPPTGLSMGLDATTLSWRDLALSMIVVSDNAATDVLCLRL-GI +DRINATMAGLGLAGTRLEGDCRFLFAALQPLQTNRTTPREASRLLAAIWRNEAASGDGCA +LMRRILGAQVW-PHRLASGFPDGIRTAGKTGTLVK-VRNEAGVVSYPDGRHYAVSVFTRS +HDAKHPAQDRAIGQAARRAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Deltaproteobacteria bacterium RIFOXYA12_FULL_61_11 TaxID=1797896 RepID=A0A1F9MBW3_9DELT +--ELQRRTLPIVRSFQGELGLYVRVIGKRGVY-DLHAQSPFYLASTVKVPLLVALLHEAR +EGNLDLRQRITLSREHYRDGGHHLMALPEGTLSLEEVASYMVEKSDNAATDLLFDRL-GV +ERVNHLVRELGFAELGPLLPMLEVRRAFYSSGYNTSTLEAFAGFLERLYLRQVLGDPYDG +KVLNLMGRCETGANRLRKHFPPQATFAHKTGTQHQ-LVVDLGLAELPCVQGVLIAAYARK +FK-TRTGGDAALASLGRATLQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Veillonellaceae bacterium DNF00751 TaxID=1384082 RepID=A0A134CND5_9FIRM +hdRTLQRIQQQLQSQDGIYAVYFQPCKAGALP-VIYNDHTMRSASMIKVFILSAAMEQIK +QGKMSFDQTITLQEADKVGGAGSLCGYPDGSVDVRTLLKLMITQSDNTATNLMIDLV-GM +DAINHYMQQHGYTETRLEWKMMA-QTAPGETRKNRTSVRDLGTWFRRVYEKKCVDPALDQ +YMIDLLLGQTD-TECFPTALP-EAKIAHKTGEVTN-LYDDGGIIFTSHGD-YILCIMTDQ +IAR--YDGIETMKKIARMLVE-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. WB02_MRS01 TaxID=2605777 RepID=UPI0012B1F8BC +------EIIEKLEQLPGRISFLYENLKTGDGF-AYHEQEPMMAASVIKLFIMAAAFEKSK +KGTFQMDELFAVKKEDCVPCGALTYLHDGILVTGLDLVTLMIIFSDNTATNVLIDIL-GM +EEINETIQGLGFERTILQRKMYDMVRS-AQGIQNYITAYETGRLLKMMYDGTLIDRQSSD +TMISILKNQQL-CSKIPFYLQDSPEIAHKTGEDT-GITHDVGIVYGK--EPFL-VCFCGN +ET-DTPAFERVMAEIS------- +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. 14171R-50 TaxID=2703789 RepID=A0A6B9YWW2_9SPHI +-kKLTAQLQTAVKGFNGQVGIYVQNLKTGKSA-AINADTLFPTASMIKVSILSGLMDKIE +KGEMQYNQKLVYRDSLLYPGEDILGSFKDKDIQLSKVALLMITMSDNTASTWLQKLV-GG +DYINTWLEQNGFKVMRVNSRIPARRAIWEIYGWGVTTPLEMCRLFTMIRTGKVVSPAASE +RMYRMLNRIYW-DDKALSQVPPYVQTISKQGAVD-ASKSETVLVNAPHGD-YVFSVITKN +NKDQDNEADLLIKKVSALLWHYf +>[subseq from] Uncharacterized protein n=1 Tax=Pontibacillus chungwhensis BH030062 TaxID=1385513 RepID=A0A0A2USL8_9BACI +-nKIDSKVEHLISQKNAPYSILIRN--NNRTIiSKNENIPFRAASVIKVPIMMEAFRKHR +EGKLNLDKLHTIKPSEEVAGAGVIHYLSGQQYSLRQLIELMIIVSDNTASNLVLKAV-GM +ESVNSLMYQLGCENSILERFFMDSA-AVEKGFENRTTAGDMITCLQAINEHPLFSKEDQI +AMKKILHNQQCKDMLGSFTSTEEIEIFHKTGELE-GAQHDVGFFEYKGQ-SVYAAVLTDD +LTKN-QEGREWIASIGQLIAE-- +>[subseq from] Serine hydrolase n=1 Tax=Nocardia sp. Root136 TaxID=1736458 RepID=A0A0Q7NGL2_9NOCA +---------------------------SAGEV-SVGGHDRVVVASVYKLLLLAAFLRQVD +HGLIDPAGRLTIDPADCTPPTGLAALHDPVTLSRRDLATSMMTVSDNAAADVLLGEV-GL +AAVGELLQELDLTDTRIVGGTADQHLAYDPSYASATTPEEMTRFLWKLWSGDIVSTASTE +FARTAMSKQIW-PHRIAAGFPRGVLVAGKTGTIGV-IRNEVAVIEFPGETPVAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Rufibacter tibetensis TaxID=512763 RepID=A0A0P0C832_9BACT +-qKLTRKLQDLTKSFQGEVGIYVRHLKTGKMV-AINADTLFPTASMIKVPIMVGVFDKIE +KGELNPKAILRYRDSLYYAGEDIVGNFKDSSVALSKIQMLSITTSDNTGSLWLQHLTGTG +TAINAWLEQNGFEHTRMNSRTPGRRANWQKYGWGQTTPREMASLVTMIREGKAVSPAASE +RMYRNLGRIYV-DDVALSQIPPTVQTASKQGAVDQ-SRSEVVLVNAPHGD-YVFCIITKN +QKDENNAGYALIRAVSSTLWNHf +>[subseq from] serine hydrolase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=UPI0006A945E9 +---LREDLMKVVHECPGSVSFTILS--HDESL-SWEENRRKSSASLIKLPIMMTAFEQIQ +TGSLNGDAMVVLRHEDHVEGAGVLNGHDGITLSIEDLLKLMITVSDNTATNRLIELI-GK +DSINRFCLTWNLKRTFLNRKMMDFRS-LEMGQDNWTSSMDVVSCLKGINEGPF-KEASKR +KMLTMLSRQQF-RDKLPALVGGDVKVFNKTGELP-GVEHDCAILESTSGKIAYVAVLIDG +LQAP-EDGRRAISRIGKLVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium TaxID=2044944 RepID=A0A431MC52_9SPHI +-kKLTRQIAQIMNGFHGQVGIYVHDLHQNKVV-QILADTVFPTASMVKIPIMIMLMDKMK +SGELAYHQPFTYSDSLVYPGVDMLASFKSNEIELSKLMLLMLSLSDNTASLWLQQIAGGG +TRINALMDSLGYQQTRVNSRTAGREANRNAYGWGQTTPYEMANIMERMVAGHLLGQPYDA +KMLRLLGRNYW-DEEAISQIPADVFVASKNGAVD-ASRSEVLFVNGKKA-SYIFCICTNH +NSESNNEAWELTRKISKLLWDYy +>[subseq from] Beta-lactamase class A n=1 Tax=Fretibacterium fastidiosum TaxID=651822 RepID=D4M750_9BACT +-------IYERIAKLDAFTGLYVEAIESGEVV-EINPNRALCSASIIKLPILALALKDVG +EGRLDWKKTYQIASANRVGGTGVLRELDEIRASLEKLAFLMIALSDNIAANQVIDLI-SM +DRITPFCRSLGYTNTRCERKQLDMQ-AIREGRNNYTSAGDAGRMLSAVARGELVNPVASR +LIHSIMSRQMC-RNKLPAKIPAIVLAANKTGELLD-VQHDAGIFTLPDGRRYVIAMLTGE +VK-DANDAVNAIADVSRIVYDA- +>[subseq from] serine hydrolase n=1 Tax=Heliorestis acidaminivorans TaxID=553427 RepID=UPI00124C8315 +-nQLEEKIKSQLYRFGGTYGLYVEDLTTGNKL-EINADKSFPAASVIKVPLVLFLYSLAL +DDRVDLDEKIVFEEKDREAGTGILKTAVGSSYTLRQLAQYTIEYSDNSATNMIMRRV-GR +ENFYFFLRLMGAEIIPLGPG-----------KGNIMCARDAGLYLKGVMVLRELHPEYGQ +EILQHLLNSKF-EDRIPAGVPQGVQVANKIGTQVN-VINDAAIVLLEGR-PYILAVLTSH +IHE--QEAVGAIAQISRLIFEH- +>[subseq from] Beta-lactamase class A n=2 Tax=Algoriphagus locisalis TaxID=305507 RepID=A0A1I6XKT4_9BACT +--DLTSEINDLLKTFNGDVGIYVEHLPSGNKV-EINADTIFPTASIVKIAILLGVFDKIE +KGELHYREPLVYRDSIKYGGSGIMQYFQDSTTDLSTLLALMLSYSDNTTSLWNQALAGGG +ADINVLMEKLGYQNTRVNSRTAGRESIWEKYGWGQTTPREMADILIRLNNRELFSPAASE +QMYRLLSNTFY-NDYAISGIPPGVNVASKQGMVN-ASRSEVFLVNSPQGD-YVCAIFTKN +NEDKDNEAWVMTRKLSNLVWNHf +>[subseq from] serine hydrolase n=1 Tax=Actinomadura macra TaxID=46164 RepID=UPI00082DA05C +-----ERIEAAFRDAGVTGFLHAVDVDTGRDV-ALRASAPVVLASVFKVPLLVAFHRQVA +DGTLDPSEQLTLRPQDRTAGPTGLSALLDEVMSLRDLACLMITVSDNASADVLLERV-GL +DAVNATAAALGLADTRIEGSGRELFEALDPAVTSRSTPRDMSHLLGRIWRDEAAPPAECA +AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-IRNEVGVVEYPDGGRYAVAVFTRS +LLLDLPQADAVIGTAARLAVE-- +>[subseq from] zinc-ribbon domain-containing protein n=2 Tax=Lactobacillus brevis TaxID=1580 RepID=UPI0009489173 +----KKDIGVTVGAIGGTNSVYVSPVNSEQSV-VV-NNGSQRSASSIKIYIMVTAYAMAK +EGVFNLNDTHTLTNDEKVGGTGVIQNMRAGTLSYREIIEYMIDDSDNTGANIMIDKLGGF +QLINNKIKSMGATDTKLRRKMLDTK-ALDNGRDNTTSARDMGTTLKMIYNHHLVSREADD +EMLAILRKNQN-RTKLPNQLPSTATVYNKTGEYDYGVQNDAEIVRNSQGA-FVAVVLSED +GEET--DQLAAMNKLGLM----- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces fungicidicus TaxID=68203 RepID=A0A494V2J7_9ACTN +----LARIDAAFADAGVTGRLHALDIDSGAQL-GTGADQPVCTASVHKLCLLVALHELAA +AGRLDLTEQVESPPADRTAPTGVAAMLDAARMSLRDLAYLMVAVSDNAAADLLLRRV-GL +DAVNATTARLGLTATLAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACPPEHGA +AVRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +GHATLPAADAVIGTAARIAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535DR39_9CHLR +--ELVQHLDQLVSSFPGGAGLWIADPNAAKPLySHDADEPVITASLYKLAVLAEAERRVD +AGQLHYSDVITIENEDITEDGSF--EVAGTELTLDQALEAMITISDNGAALALWHVL-GA +DNINATLRNVGINDFHVFVA--------WGEDANVATPRAIGTLLTLLAKRQLISAAASD +RMLARLERQQI-NDRLPAELPEGVVVAHKTGNLP-GLTHDAGIIYTPSGP-RVVVAMTWD +AY--DADAYAFIANVGSIVYS-- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. Go-475 TaxID=2072505 RepID=A0A2Z5K3U5_9ACTN +----LARIHAAFADAGVTGRLHAVDIDTGAQL-DAGADQPVCTASVHKLCLLVALHERAA +QGALDLTEQVDCPPEGRTTPTGLAAMLDGARLSLRDLAYLMMSVSDNAAADLLLGRV-GL +DAVNRTTARLGLTRTRAVHTFGELLAALDPARTNRSTPRDMTRLLAAVWRDEACPPEHGA +AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT +ARTSLPAADAVIGTAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=UPI0006B5D12C +--ETEKRIENVIHAFSGHISFYAEHMQTHETL-IHDSDHVMETASVIKLPIMAATFQYLV +DEHKSLADPLTLQVEDVVDGSGILQYLSPGLLSLKDVMTLMIIVSDNTATNMILRYV-GI +PHVNRFIQSLGLSQTRLLKRIDF---TIPG-PIGLATAKELGTILTQLYHRTLVNKDASE +IMWDILCRQQY-NTIMTRHLPPRVQIGSKSGSLE-GIRNDVGIVVTPWGD-YVLAILSER +SRHIDNEALVVLPRISRFIFDYf +>[subseq from] Uncharacterized protein n=1 Tax=Megasphaera genomosp. type_1 str. 28L TaxID=699218 RepID=D3LTR8_9FIRM +hdRTLQRIQQQLQSQDGIYAVYFQPCKAGALP-VIYNDHTMRSASMIKVFILSAAMEQIK +QGKMSFDQTITLQEADKVGGAGSLCGYPDGSVDVRTLLKLMITQSDNTATNLMIDLV-GM +DAINHYMQQHGYTETRLEWKMMA-QTAPGETRKNRTSVRDLGTWFRRVYEKKCVDPALDQ +YMIDLLLGQTD-TECFPTALP-EAKIAHKTGEVTN-LYDDGGIIFTSHGD-YILCIMTDQ +IAR--YDGIETMKKIARMLVE-- +>[subseq from] Serine hydrolase n=1 Tax=Inquilinus sp. KBS0705 TaxID=2578108 RepID=A0A554SNA5_9PROT +--KLSAQLQTATKGFNGTLGIYVQNLKSGKTV-EINADTLFPTASMIKVSILSGLMDKIE +KGELRYNQKLAYRDSLLYAGEDILGSFKDKDIQLSKVAMLMITMSDNTASLWLQKLV-TG +EHINQWLDANGFKVMRVNSRTAGREAMRNIYGWGVSTPREMARLFTMIHDGKVVSPAASE +RMLRTLNRIYW-DNTALSQIPPNVQAISKQGAVDD-SRSETVLVNAPHGD-YVFSVITKN +NKAPTNEADILIKKVSALLWHYy +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus actinosclerus TaxID=1768108 RepID=A0A0U3T4A8_9DEIO +------------AGFTGVVGLHVTDLAGTELA-AWNAGRVFPAASTIKVPLLVLALQEAQ +AGRLDLSGRVVMQPGDRVPGAGVLHELDGGLLTWRDVLTLMIIVSDNTATNLVIGRL-GV +DAVNTWLAAGGLTGTRLVGKLEQRTEAQRRGERNATSARDQTALLRALVAGQLLDEAHTA +LALDILGRQQY-RDLIARHVPCGYRSATKSGELH-GVHHDVGVLFTP--YPLLVALLSEG +GADPR------------------ +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter terrigena TaxID=2492395 RepID=A0A4Q5LMH1_9SPHI +-qKLTAQLQSLTKKFNGQAGIYVQNLKTGRTV-EINADTLFPTASMIKVSILGGLMDKIE +KDVMQYNQKLVYRDSLLYPGEDILGSFKDKDIQLSKVAMLMITMSDNTASTWLQKLV-GG +DYINTWLEQNGFKVMRVNSRIPTRRPIWEVYGWGVTTPREMCRLFTMIREGKVVSTAASE +RMYRMLNRIYW-DDKALSQIPPYVQAISKQGAVD-ASKSETVMVNAPHGD-YVFSIITKN +NKAPDNEAGLLIKKVSALLWHYf +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A4P5V4D6_9CHLR +------------------ASIAVVHLETGASA-TVNGDRIAAPASLYKIGVLVEAFRQIE +AGLLRLDETLRLLPIDWAPGAGILQGRIGTQVTITDALRLMIGISDNTAAHAIVRRI-GV +DRVNANNQRLGLSNTRY----------YIDDRPDTTTAADMARLLSLLATGRLAGVEATG +QMLDLLQQVQP-AAWLPRGVPPTIAVAHKSGQLD-AVRNDAGIVFGPTGR-YVVVVLTDN +RP-NAMNGENAIVQVARSVHAYf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-37 TaxID=1463903 RepID=UPI0004CBDF42 +----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVPTASVHKLCVLVTLHEQAA +AGLLDLTEQVECPPAGRTTPTGVAAMLDAVRMSLRDLAFLMMAVSDNAAADLLLRRV-GL +DAVNATTARLGLTRTLAVHSFGEMLAALDPARTNRSTPRDMTRLLAAVWRDEACTPEHGA +AVRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus paraplantarum TaxID=60520 RepID=A0A4Q9XZ01_9LACO +--QIKADISATVGVISGTNSVYVSPVDSHATV--LVNNESQRSASSIKIFIMVTAYAMAK +EGVFNLDDIHTITDSEKVGGTGVIQNMDAGTLSYQEIIEHMIDDSDNTAANIMIEKLGGF +QLINNKIKSMGATDTKLRRKMMDIK-ALDAGRDNTTSACDMGITLKKIYNHQLVSQQADS +AMLTILANNQN-RTKLPKRLPDAATVYNKTGEYDYGVQNDAEIVKNQRGA-FVAVVLSEN +GEETD--QVDAM----------- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A2Z4MRX6_BREBE +--ELEKRLSTIIGQAEGTWGVVVEEVAKGIRF-EHVPNERFIAESVIKVPIMAAVFAASE +QGHFRLDDQLVLRQEELVGGSGILHALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK +AQIDQTMIDLGMRQSCYSRKLMIYP--LDVTENNTITAGNVASMLGHLATGSYLSEHACK +EMIAIMKKQQV-RNGLPSQLPNEWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKE +VT--AQSALNTLGLLGRAVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sulfobacillus thermosulfidooxidans (strain DSM 9293 / VKM B-1269 / AT-1) TaxID=929705 RepID=A0A1W1W922_SULTA +--EAEKRIEDIVHAFSGHISFYAEHMQTHETL-TREPDRVMETASVIKLPIMAATFQYLA +DEHKILSEPLTLQVEDMVDGSGILQHLSPGLLSIKDVMTLMIIVSDNTATNMILRQV-GI +PRVNRFIQSLGLSQTRLLKRIDF---TIPG-PIGLATSRELGMILTQLYHRTLVNKDASD +IMWDILCRQQY-NTIMTRHLPPKVQIGSKSGSLE-GIRNDVGIITTPWGD-YVLAILSEH +SRHIDNEALVILPQLSRIIFDYf +>[subseq from] serine hydrolase n=1 Tax=Actinomadura bangladeshensis TaxID=453573 RepID=UPI0013D18A53 +-------------AAGVTGFLHVADMDTGREV-AVRAGEPVVLASVFKVPLLVAFHRRAA +AGLLDPAEQVTLAPGDRTAPTGVSALLDEVRMSLRDLTCLMITVSDNAAADAVLDRV-GR +DAVNAAAADLGLRGTVVEVNGRELHEALDPARTSRSTPRDMTRLLSMIWRDEAAPPDHCA +AMRRLLGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-VRNEVGAVEYPDGARYAVAVFTRS +TLAVLPRADAVIGTAARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Candidatus Melainabacteria bacterium TaxID=2052166 RepID=UPI001181FD1B +--DLKARIEQLFAEYKYTPHFYFYNPQTNTYV-EINGYGPAPAASVIKLPILLDYLMSLD +ENLITVDTPLLYAEFHRAGGAGELQYRPTGQFKANDVASQMIRISDNTCTNMMISYLGGT +DAVNQRLSDLGLVNTRIRNWLPDLTGT------NTISPYEMVTILNNIDHGPVISEVSRY +NGISILESTHN-RRLLVAPLPNQAIVAHKTGDIGT-AIGDSGIVYMPDGRKYYISMQVER +PYND-YTVRDMVQRTSRLLYDY- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A4U0M7H5_BACME +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIVVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLKIQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. Tu 4128 TaxID=1120314 RepID=UPI000F0152F5 +--ATAARLGAAFAEAGVTGWLHAVDVDSGAQV-EAGADQAVCTASVHKVCVLVTLHEQAA +AGTIDLTEQVECPADGRTPGPTGLSAMLDPVLSLRDAAFWMMSVSDNTAADLLLRRV-GL +DAVNRTTERLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLTAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A0L1LTY8_BACME +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIVVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLKIQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora hirsuta TaxID=1837 RepID=A0A5M7C9B8_SACHI +-----------AADLPGRVGFAAWDLAEREPV-LLGAERVVPAASTIKVLVMITALRAVQ +AGRIGLDDPLDLPAE-RVGGAGLLRQLRSIEISLRDLITLMIVISDNAATNAVIDAV-GF +DAIRDCAADLGCTGTRVERRLMHHHEP----GRNETTALDQARVLDRLAGGAALPPDLTE +HALGVLAEQQV-RDRLPARLPAGATCWNKTGELL-GLRHDVGLIGA-DRPRAVIAVLVDE +LTDE------------------- +>[subseq from] Serine hydrolase n=1 Tax=Bacteriodetes bacterium TaxID=2507565 RepID=A0A521X1W1_9BACT +-------IQTTINELGGRVGISAKHISTGETL-TIDGDSLFPTASIIKLPVLVELFYQFH +EGKLSPDTPIPLLDDAKKPGSGILSYHNGQTLKLIDIATLMMIESDNTGTNYVIDQLGKL +NAVNNRMKSLGLQHTKLQNKLYSFATEAKRYGIGFTTPNDMLLLLEKIVKGEIVDRATSD +SIIAMMKGQQY-LEMAPRYLPSTLWTANKTGSLDE-VKNDAGIVSSSKGT-YIYAIFIDN +SPQIDNKATLTVAKISQILYNYf +>[subseq from] Uncharacterized protein n=1 Tax=Abiotrophia sp. HMSC24B09 TaxID=1581061 RepID=A0A1F1LPK4_9LACT +-qAVQSAFSDLYGTKSTKLAYYFQEVTSKGTA-LVNQSGPIKSASIIKLFIMQVLLEEIK +AERISWQEIISMMAEDQVGGTGNLQAEPGTSYSLEELALEMLIHSDNTATNLIIERLGGL +SAVQAKIQSLGYQDTRLQRLMMDQ-AAIAEGRENFTSAREVGQLLAKLYQHKLVGQEQDQ +IFLDYLAQQTD-RQGLVALLPQGVISYNKTGTNSQGLQHDAALVQLTNQSAYVLVVLQEG +PGD--GDLLKPLQEIGQQV---- +>[subseq from] Beta-lactamase class A n=2 Tax=Saccharopolyspora TaxID=1835 RepID=A0A1H6EKX4_SACHI +-----------QAELPGRVGFAAWDLTEREPV-LLGAERVVPAASTIKVLIMISALRAVQ +AGRIGLDDEVELPAE-RVGGAGLLRQLRSVDISLRDLITLMIVISDNAATNAVIDAV-GF +AAIRDCAADLGCTGTRVERRLMHHHEP----GRNETTALDQARVLDRLARGAALPPELTE +HALGVLAEQQV-RDRLPALLPVGANCWNKTGELL-GLRHDVGLLGT-DRPRAVIAVLVDE +LTD-------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Caulobacter vibrioides TaxID=155892 RepID=A0A0V2F688_CAUVI +-eAMSLKLAAIAERAPGDLGVAVQDLTTAQRA-ATAGDHLFPLAGIWTAALGAAVLAEVE +AQALSLRETLTIEDVDLSPPSGVADVWPGRRWTVEELLKRAVADGDNTAADVLMKRIGGP +GAVTAWLDLKKVENLRVDRYARQLLPDYLADPHDSTTPLAAVRFLEALNQGELTDQDGRR +RMLRMMEAAA--GDRLRPALPAGARLAAITSATPAAADNVLAMVRLKDGRRFALAMFLKA +SPLEEADRDALMLDVMRTVLQ-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudoxanthomonas sp. SGD-10 TaxID=2493089 RepID=A0A426HB95_9GAMM +------------------------------------------------------------ +----------------------------------------------------------GE +PRLQALADALGVPRAELDTTLEQVFEDYYARGLNSATLPAYGRLLERLASGELLSPRSTA +LLLGHMRAISTGSRRIQAGLPAGADFAQKTGTQQQ-RACNVGLLDPGGRDGATVVVACAE +HFGELEQAEQAFQALGRALA--- +>[subseq from] Serine hydrolase n=1 Tax=Kibdelosporangium phytohabitans TaxID=860235 RepID=A0A0N9I579_9PSEU +----AAEIAAVFADAGARGFVHARQVGDGPEV-AVGADDQVVLASVFKIPVAVAYAREVA +AGRLDETERTRVTARYRIGGVGTAGCADDVEMSWRDLAHFMLTMSDNAATDLIYHRV-GQ +AAVDQVLADLGLARTRLIGCCEDLFAVVDPDRTTSSTPREITALLDAIWTGRAGDPAACE +RVRTIMAQQIW-PHRISSGFPTGVTIAAKTGTLP-AVRNEAGVVTHVDGRQYAVAVFTRA +DCDRLPAVDAAIGQAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces silvensis TaxID=1765722 RepID=A0A0W7X493_9ACTN +-----TRLKEAFAEAGVTGRLHALDIDSGAEL-GTGADHPVVTASVHKLCVLITLYEQAA +AGLLDLTEQVECPPDGRASGPTGLSAMLDPVMSLRDAAYLMIAVSDNTAAELCLSRV-GL +DAVNATTARLGLTRTRALHTFRAMFEALDPARSNHSTARDMTRLLRALWRDEACTPEHGA +AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA +ARATLPPADAVIGTAARIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Saccharopolyspora TaxID=1835 RepID=UPI000B81E7A7 +-----------QAELPGRVGFAAWDLTEREPV-LLGAERVVPAASTIKVLIMISALRAVQ +AGRIGLDDEVELPAE-RVGGAGLLRQLRSVDISLRDLITLMIVISDNAATNAVIDAV-GF +AAIRDCAADLGCTGTRVERRLMHHHEP----GRNETTALDQARVLDRLARGAALPPELTE +HALGVLAEQQV-RDRLPALLPVGANCWNKTGELL-GLRHDVGLLGT-DRPRAVIAVLVDE +LTD-------------------- +>[subseq from] serine hydrolase n=1 Tax=Actinobacteria bacterium OV450 TaxID=1592328 RepID=UPI000D14BB10 +-----HRIGAAFAEAGVTGRLHAVDIDSGAQI-DAGADHPVVTASVHKLCLLVALHQQAE +AGRLDLTEQVEVPPPDRTAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLART-GL +DGVNEATARLGLTRTRAVHTFRSLFAALDPARSNRSTPRDMTRLLAALWRDEACTPEHGA +AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA +ANATLPAADAVIGTTARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Ktedonosporobacter rubrisoli TaxID=2509675 RepID=A0A4P6JVW5_9CHLR +----QEQIEQELARLGGRSSCIVMRMEKQDLV-SINPNTLYPAASLVKVPILLEVARQVA +SGRLSWEEGHAVPEAARATSAGVLADLSAELLSVHDLAHLMITISDNTAANVLLDLV-GM +DAVNATMQELGLPSIRLERHFMDLEAR-AAGRDNWATAGDMARLFAYLCTPEV---PERE +HIIDFLLQQND-TTILPAYWGEDIPFAHKTGGLA-GIIHDAGILFPQQKMPLIIVAMTAD +QS-DEPLTRYVLARVGQLIYQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Actinobacteria bacterium OV450 TaxID=1592328 RepID=A0A0N1NMR3_9ACTN +-----HRIGAAFAEAGVTGRLHAVDIDSGAQI-DAGADHPVVTASVHKLCLLVALHQQAE +AGRLDLTEQVEVPPPDRTAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLART-GL +DGVNEATARLGLTRTRAVHTFRSLFAALDPARSNRSTPRDMTRLLAALWRDEACTPEHGA +AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA +ANATLPAADAVIGTTARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Eggerthellaceae bacterium zg-893 TaxID=2682778 RepID=UPI0013EB7C49 +--NLAATVSGIISSYGANASVTLSDLDDYATF-AVDGSEPHVSASMIKLAIMAEVFDQVN +NGYLALEDSYTVQESDIVGGTGTLQGGPGTQLSLSDLVRHMIAESDNVATNMLIDLV-GM +DAVNEEAAKLGLNATSLQRYMMDTDAQ-AAGIENHMSSDDAAVILILIANGEFYTPELSQ +LATDFLSQQTD-AGGIAGSLSSGETFAHKTGTLTN-VRHDAGIVQ--GEAPYVLSVFVEG +TDEG--SALSLMGEVT------- +>[subseq from] Beta-lactamase class A n=1 Tax=Aminivibrio pyruvatiphilus TaxID=1005740 RepID=A0A4R8M6U0_9BACT +-------VHKEIEAFPETAGVVVRSSSDGVEV-THNPGKVFSSASLIKLGVLYTLFSKNA +AGGIDLDEWCDFSSAASVDGGLLHRVRSGGRFRLDDLALLMISVSDNTAANLLIDRL-GM +DTINGGFRELGLTGTVLGRKMLDFEAK-KAGKDNYTTAGDVAVLLETLHSGKNLPVSARN +RMMEILSAQKL-NSKLPGMIPVELFLAHKTGELP-GNEHDAGIFFYRGKKPVVVSVLTEG +LQ-HRSGGVSFCARIGRIIYDAy +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. SLBN-134 TaxID=1081603 RepID=A0A542WCQ7_9ACTN +----LARIDAAFADAGVTGRLHALDIDSGAQL-GTGADQPVCTASVHKLCLLVALHELAA +AGRLDLTEQVESPPADRTAPTGVAAMLDAARMSLRDLAYLMVAVSDNAAADLLLRRV-GL +DAVNATTARLGLTATLAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACPPEHGA +AVRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +GHATLPAADAVIGTAGRIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02488 TaxID=1703920 RepID=A0A1Q5NC16_9ACTN +------------------LHVAELHRPSARVV--IEPGEQLPLGSVYKVPLMAAFCRLAD +TGRLDPRHRVTLEPADRVPPTGISVLHDPVTMSLRDLVTLMMTVSDNTAAAAVLRAV-GA +DAVDAFCRDLGMPDTRIHGGVVATFSVYDPASKASGTPADMARLLRAIWTDEAASAEGCA +FMREVMRRQPW-THRLASGFPDDVTVYGKTGTFGS-LRHEAGVVELADGSTYTAVVFTQA +ARADLPRADAVIGAAARAAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. 7K502 TaxID=2530387 RepID=A0A4R4YJC4_9PSEU +---VERRIREVLADAGAEGWVHAKPLNSEREI-DVGGDELVVTASVYKLPLLVALCRAFD +AGALDPRARVRIDPASCTPGPTGMSAFQDPVVSWRDLAASMIGVSDNAAADLILGEV-GL +DALADTLADLGLSRTRVVGGTADSHAAYDPSYASATTPREMTRLLELVWADAVASPEQCE +FIRRLLANQAW-QHRIRAGFPRGVRVAGKTGTIG-AVRNEVSVVEFDGETPVAVAVFTLA +ARADAPGVDAAIAECARIAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Desulfovibrio sp. X2 TaxID=941449 RepID=S7TKB6_9DELT +------------------------------------------------------------ +------------------------------------------------------------ +-------RDARDGATRLDRAEPELNEATPGDPRDTTTPAAAAASLAAVVLGDALAPSSRA +AVTDWMLHDQVADGLLRAALPPDWRIADKTGAGGHGSRSIIAVVWPPERKPLVVAIYITQ +TEAPLPAANLAIARIGRVL---- +>[subseq from] Beta-lactamase class A n=1 Tax=Deinococcus peraridilitoris (strain DSM 19664 / LMG 22246 / CIP 109416 / KR-200) TaxID=937777 RepID=K9ZXE4_DEIPD +------DLQFLLASHPGTVSVRVLSLQGEVLF-DHQSERPFPSASLIKVPLLVRALWHVQ +QGQARLEERLTLRAYERVPGSGVLSQLDAGLLTLRDVLTLMTVVSDNTATNLVIDRF-GL +HDVNVFLREAGMNNSELIGQLQRQNERQRAGERNRTSAHDISRLLLRLVRGELLSPALTD +LALDILSRQQV-RDIIARHVPRGYRVASKGGELS-GVRHDAGIVWTP--RPLILALLSEG +GSLREHPDNR------------- +>[subseq from] serine hydrolase n=1 Tax=Sphingobacterium sp. 1.A.4 TaxID=2044603 RepID=UPI000C0BCFF0 +-kKLTAKIQQEINGFRGDIGIYVKNLKSKKEV-RISADSIFPTASIVKVPLLVGIFQKID +ANEVQLEQKFIYSDKRTYGGSGLMQFYKDSATDLSTMISLMLTYSDNVTSIWIQELAGGG +QTINPLMDNLGLKNTKVNSRTAGREDIWKKYGWGQTTPYEIAHLFELIREGKVISEKQSD +KMYRFLKNQFY-NERSLSQIPAIYATISKTGSVND-ARGEVVLVNAPHGD-IVFSILTKN +NKTKDNEAENLTRRIAKIIWDHf +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A1I2T6J6_BACME +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILGLTSVIQRMEKNTVGGAGVLKALPQLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMQGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Nocardia donostiensis TaxID=1538463 RepID=UPI0009DAFDD3 +--------------------------GSADEV-SVGGGERVVTASVYKLALFIAFCRCVD +AGLIDPAEPLTVHPAECTPPTGIATLHDPVTLSRRDLATSMMTVSDNAAADVLLGEV-GL +RAIEDLLTGLGLTQTRIVGGTADIHRAYDPAYTSATTPEEMTRLLREVWSGAVLSPGQTE +FVRAVMRNQIW-PHRIASAFPRGVSVAGKTGTVGI-IRNEVAVVEFPDEYPVAVAVFTRA +ARADLPIVDAAIAETARVAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Clostridium sp. KNHs216 TaxID=1550235 RepID=A0A542ANK0_9CLOT +---LRDYAENEIQDINAKVSLLVYDFDQDETLlSFYEKDRVVSASTIKTPILLTALDMVQ +SGKLSVGQMLRLPGEEILDDTEVFDRGVR-EYPLEELLTWMIINSDNTATNVLIEFL-GM +DAVNACCRKLGLKATALERKMLDWEA-VRQGRNNYTSAQDQLTVFQSLRRASILTPELCR +CALGILERQRDFSMALRYIADRDFSAAHKTGGLDY-LNHDTGIFSLPGHE-YYFGCFVTD +STDDTDENKKLIGRLSRKVYDYy +>[subseq from] serine hydrolase n=1 Tax=Nocardia salmonicida TaxID=53431 RepID=UPI0007A4B5F6 +---------------------------SAGEV-SVGGHDRVVVASVYKLLLLAAFLRQVD +HGLIDPAGRLTIDPADCTPPTGLAALHDPVTLSRRDLATSMMTVSDNAAADVLLGEV-GL +AAVGELLQELDLTDTRIVGGTADQHLAYDPSYASATTPEEMTRFLWKLWSGNIVSTASTE +FARTAMSKQIW-PHRIAAGFPRGVLVAGKTGTIGV-IRNEVAVIEFPGETPVAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Kribbella flavida TaxID=182640 RepID=UPI00059B712F +-------LSGVFDDAGARGWFHAVSLDRPDEQiALDADHVVPMASVYKLPLVVAFSELVD +RGELDPRQPLTLEPGDRTPPTGVSILSDPVTMSLRDLAASTMAVSDNAAADALLEVV-GL +DRVADFLRRHGLTDTRVRRGTAGNLRIYEAAGGSSTTAQDMTRLLAMLWAGAILSAEQTA +FVRRLMELQVF-GQRIAAGFPDGVRVYGKTGSFG-ALRHEVGVVELPGGPTVALAVFTRA +ARADLPRVDAAIAHAARYAAD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. AG236 TaxID=2184002 RepID=A0A369C456_9BACI +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIVVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRK +KIMRMLKIQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522E036_9BACT +-kRLQKELEAVVKEFNGDIGVYIKNLRTGKTI-AINADTIFPTASIVKVPVLIGIMDKIS +KGELLYDSTLIYKDSLLYEGEDILGSFKSDEILLKKVIMLMLTTSDNTASLWLQSLAGKG +TRINEILDSLGFKNTRVNSRTPGRENNRTQYGWGQTTPMEMGTIFEKIYLNEIFSAKACD +RMMRCLGRNYWDVDEAVSQIPPYIEVFSKNGCVD-ASRSEVLLVNAPHN-PYIFSIFTKN +NKTHNNEAWTLARKISALLWNYf +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=A0A370FPT8_9BURK +------------------------------------------------------------ +--------------------------------------------------------RNGP +ARVEAIRRAADVKRTDLATTMDEAYDRYYRRDLNTTTLIAYGAMLERLVRGQVLPDAPRA +LLYKAMKHDIYTGYRLQAGLPRDHAFIHKTGTQHR-RACHAGVLDPDDLQKALVIVACTA +DLDEQKQAGPVLESVGRAI---- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus sp. OK519 TaxID=2135729 RepID=A0A2T5KLY3_9NOCA +-----------------------SDGHGGIEI-GTAADEPVVMASVYKLPLVVTFCRLVD +AGDLDPREQVVLDPSNRTTPTGVSQLSDPVRMSLRDMARSMMALSDNAAADELLRRV-GV +DRVNETMRGLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTGLLSAVWTGAALSAEQTA +FVRGVMASQVF-TARLRSGFPGDVVVAGKTGTLG-AVRNEVGVVEFPDGDAFAVAVFTRA +ARADLPRADAAIGIAARAAI--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces violaceorubidus TaxID=284042 RepID=UPI0004C2A11E +--ATAARLDAAFAEAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKVCVLVALHELAA +AGELELTEQVECPPTGRTPGPTGLAAMLDPALSLRDAAYLMMSVSDNTAADLLLRRV-GL +DAVNRATARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGALWRDETCPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium UBA8153 TaxID=2060924 RepID=A0A3C0FFP9_9FIRM +-eKLRHQVEEITSSVPGTIGVAVKDLATAEEF-HYQADQLYPLASVFKIPILVELYRQSG +LGLVNLDERYTLTAGIKSLGSGVLRDRPGATMTLWDYALLMIIISDNTATDLVAGVV-GI +HHVDPTLRRLGLERTSVTKDCYHLLCLYPEPTHNFSTPREMNRLLGQLVEGELLGPPEQA +GVMDILLRQQL-KQRLPYLLPRPVPVAHKTGSLP-GVFNDCGIVFRDKQPAYLISLMSKG +VS-AALEGPLVLARVSRAVYDA- +>[subseq from] Beta-lactamase class A n=2 Tax=Granulicatella balaenopterae TaxID=137733 RepID=A0A1H9JSX6_9LACT +----------------GNHAYYYQDLSTSEAF-GANQDTPIRSASIIKLMILAALYQEVA +DGQIDLTDSYYLKAEDIVGGTGQLQQTLGTRYSYYDLAYQMIYSSDNTASNVIIDKLGGL +AKTNQLFKQLGFKKSNLQRKFVDTNA-LYQGLDNYVTAFELADLLSRLYQHQLVTPASDR +AMLAILKENPN-RDIILKKLPRNITSYHKTGNYSYGTWNDAGIFVTDKGA-FILVSLTSG +GQ--FQQKKTATANFA------- +>[subseq from] Serine hydrolase n=1 Tax=Frankiales bacterium TaxID=1909291 RepID=A0A522B6L9_9ACTN +--DVTAALTDVFSRAGAVGRLHAREIGTGHEV-GLGADEPVVLASTFKVPVALEVFAQAA +EGGLDLSERVRVPVEGRAPGPTGLSVFSHEALSLHDLARSMITVSDNAATDVVCERV-GL +DRVAARLGALGLDEIVIPYDCRGIFAALDPLQTDRGTPRAMTRLLELIWTDTAGPADACA +QVREVMAQQVW-PHRLTAGFPADVTLAGKTGTLPS-QHNEVGVVGYPDGRSYAVAVYVRS +ARFDQPLLDRAIGEAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Gelidibacter salicanalis TaxID=291193 RepID=A0A5C7AJP2_9FLAO +---LENGLAELAQGFEGDVGIYVYNLKTQKEA-AINADTIFPTASIVKVPILIEVFNQIK +AGKLHLKDTLIYDAKRVYGGSGLMQFYKDSTTDLRTLVSLMITMSDNTTSLWCQELVGGG +LAINKTMADLGLKHTRVNSRTEGRTEDWETYGWGQTTPREMASLLIQMRERTLVDEAASD +EMYRIMGNSFYTDYSL-SQIPPYVQTAAKQGMVNK-SRSELVMVNAPSGD-YVFYIATKN +NADENNKAWELQRAISAYLWNYf +>[subseq from] Beta-lactamase n=1 Tax=Intestinimonas butyriciproducens TaxID=1297617 RepID=A0A0S2W0G7_9FIRM +--ELSAYLAAEIAAFPGKTSLLVADLPTGAVRhAWQPEEPVPSASTIKVPILLAALEEVR +LGRLSLEQRVALPAAALLPDTEVFDR-GETDCSLWELLYWMTALSDNTATNVILDLL-GL +DAVNRYATRLGLRHTVCRRKMLDAAAA-AAGRDNRTSAADQCRLYRQLCLGRLLTPRLTE +TALDLLRRQRCMDAALR-YLPYPVDFAHKTGELD-GVTHDAGVFFQGSGG-YYLGIFTWE +GPDGDPEQKRYIGRLARAIYETy +>[subseq from] Beta-lactamase class A n=1 Tax=Desulfallas thermosapovorans DSM 6562 TaxID=1121431 RepID=A0A5S4ZXC2_9FIRM +---LQEQIAGYLDKQPGVYGLYFIDINSGRGF-GYNSRTVFHAASTFKVPMNLYLYRAAD +QGQLNLSERLFFRDKHLEGGTGILQNQPPGEYTIAQLADYSILYSDNVATNILLDRL-GK +ENVKEFMRSLGGQVVD--------------NEQNITCPRDLALYMQEVLR--LARQPAGE +KLLENLFDNKL-KDRIPAPLPPDIKVANKIGTWPSETYNDVAYVAHPKQ-PYILVVTSKE +TP-GYREAVAVIRHLSELVYRY- +>[subseq from] serine hydrolase n=1 Tax=Actinomadura amylolytica TaxID=1411117 RepID=UPI000E6B5B2B +--RVAARIERAFRDAGVVGCLAAIDVDDETRRvEVRADEPVVIASVLKVPLLVAFYRQVA +AGRIDPAEQVVLRPDERTAPTGIGMLRDEVRMSLRDLAAMMITISDNAAADALFARI-GA +DTVNAVLDELGLHRTRVPGGCRELFDALDPARTACGTPAEIARLFAAIWRDEAAPPAECA +QMRRIFGLQVW-PHRLASGFPDDVRVGGKTGTLPT-IRNEAGVVEYPDGGRYAVAVFTRS +LSAVLPQADAVIGTTARLAVEH- +>[subseq from] Serine hydrolase n=1 Tax=Luteimonas sp. XBU10 TaxID=1132694 RepID=A0A5D4XSS6_9GAMM +------------------------------------------------------------ +------------------------------------------------------NAAAGE +PRLQALARTLGVARDALPKSLQDVFEDYYATGANAATLPAFARLLQRVAAGELLSDAGRA +RLLGHMRAISTGDRRIAAGLPAGTDFAQKTGTQL-GRACNVGILEPGLGDGATVVVACAE +RFGDLAQAERAFQALGRA----- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium hathewayi CAG:224 TaxID=1263067 RepID=R5TPL2_9CLOT +---IEKRIEAELMSYDGTMGIYADDLH-GNII-AIGADEAFETASTIKTYILACLFDQVE +KGKASLEDMVEYKEEHTVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL +DTINACIRGLGCRDTVLYNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPESDA +KMLEIFKKQHY-NSMITKDFPAVVTVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNRK +FSDAAHPATVFGARVSRLLFDQf +>[subseq from] Uncharacterized protein n=1 Tax=Armatimonadetes bacterium TaxID=2033014 RepID=A0A3D1IAC0_9BACT +---LQKRLDAVCRAFHGRMGYSLIVLKTGQRI-SFRGDERFPTASTIKTAVMVEAVNRVD +EGTLKWSDKRPVPPESGREASMWSYFFKDGVPDLDGWVNLMIGVSDNTATIVLREWL-GI +EAINARMERLGLTNTMVLGPVPPEKQLRSVFGLGVTTPNEMARLLELIYRGKAASPGGCE +KMIRILGRQYW-DDLIGATVPPDVKTALKSGAISR-SRSDTGIVFSDN--PYVLCVYTDN +QKAPDNEGEVAIRKIAQMVWAH- +>[subseq from] serine hydrolase n=1 Tax=Actinomadura rudentiformis TaxID=359158 RepID=UPI00124CD9A0 +--DATARIEAAFQDAGVTGFLHATDLDTGREI-GVRADEPVVLASVFKVPLLVAFYRQAA +AGLLDPREPVTLRPEDRGDPTGISVMLDEVRMSLRDLACLMITVSDNTSADTIMDRV-GV +GAVNDAVAELGLHRTHVAGTGSDLFDALDPLTTSRSTPREMARLMGMIWRDEAAPPGECA +QMRRLFGLQVW-PHRLSSGFPDDVRVSGKTGTLPT-IRNEIGVVEYPDGGRYAVAVFTRS +PTAVLPQADAVIGVSARLAVE-- +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Oceanobacillus picturae TaxID=171693 RepID=W9APF4_9BACI +-------------------QYSVLLTSGEGSL-AINEQQLRPAASLAKIPILIEACQQID +SGRLHPDKLVYIEEEQFVGGSGIISYLTNSHYSYMNLIELMMIVSDNTAANVLLESL-GM +EAVNQTIEQLGAKNTIVQRKFMDTKAQ-QEGLENYTTALDMVTLLKAISEEKYISSKSRK +FMRSILAKQQL-TNKLANFLHPSVTIFHKTGELC-GIEHDAAILECKEE-RVYITVLSDH +LP-SNAEGQHTIAQIGKHAIDY- +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus cellulosilyticus NBRC 106333 = KACC 11606 TaxID=1223518 RepID=A0A511NAX4_9DEIO +-------LAELVQRFDGELSLCVSDLQGEMLF-CHEARQVFKAASLIKLPILSCALKTVE +TGALSLQDRLPLAAQDQVPGAGVLHEMETGLLTVKDLLTLMIIVSDNTATNVLIERL-GR +DTINRHIQQIGLKDTFLVGKLPELQNEQRTGQRSTTSAADMNLWLLKLWQGQLLNPEHTA +LALGILKKQQD-RLVIARRLPRNFEVASKSGEIQY-HRHDVGIVFAE--KPYAVSLLSRG +SKDLRE----------------- +>[subseq from] Serine hydrolase n=1 Tax=Sulfobacillus benefaciens TaxID=453960 RepID=A0A2T2XCK5_9FIRM +-qQLDRIFSHIADNFSGTFTVYAEHFKTGEVI-AFGNSHPMETASTIKLPILITAMQKIH +EGHLHMEQLVPLLPDDYVTGSGVLQNLSLGTLPIADVLMLMIIVSDNMATNMILRLI-GL +DAINRLMQDLGARNTVIRKRID-FR--IPP-PIGLSTPKDMVHLLKGIYHRQLVSPAASK +WMWDVLTRQQY-NTILTRNMPPQVIIGSKSGSVE-GVRNDVGIVTTPWGD-YAIAIMSEA +CQHMDNEAHRVLPEVALQVFQHf +>[subseq from] Serine hydrolase n=1 Tax=Paenarthrobacter nitroguajacolicus TaxID=211146 RepID=A0A558GVI4_PAENT +-----EELAEIFAAVGATGYVHAREVGGGREV-SLNPDEAVVLASVFKVPFAVAYSREVS +AGRLKESDRTTVTSRYRVGGLGTAGCADDVEMSWRDLAKFMMTMSDNAATDVIFHRI-GQ +AAVDAVLDDLGLQRTRIIGCGEDMDHIMDPARTPSSTPRDIVSLLDAIWTNSAGSPETCE +RVRSMMEQQIW-RHRMATGFDDGVVVAGKTGTLP-AIRNEVGVVTYPDGRRYAVAVFTRA +TTDTQPGIDASIGKAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas sp. SGNA-20 TaxID=2493088 RepID=UPI000F635068 +------------------------------------------------------------ +----------------------------------------------------------GE +PRLQALADALGVPRAELGDTLEQVFEDYYARGLNSATLPAYGRLLERLASGELLSPRSTA +LLLGHMRAISTGSRRIQAGLPAGADFAQKTGTQQQ-RACNVGLLDPAGRDGATVVVACAE +RFGELEQAEQAFQALGRALA--- +>[subseq from] Beta-lactamase n=1 Tax=Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399) TaxID=479435 RepID=D2PZW8_KRIFD +-------LSGVFDDAGARGWFHAVSLDRPDEQiALDADHVVPMASVYKLPLVVAFSELVD +RGELDPRQPLTLEPGDRTPPTGVSILSDPVTMSLRDLAASTMAVSDNAAADALLEVV-GL +DRVADFLRRHGLTDTRVRRGTAGNLRIYEAAGGSSTTAQDMTRLLAMLWAGAILSAEQTA +FVRRLMELQVF-GQRIAAGFPDGVRVYGKTGSFG-ALRHEVGVVELPGGPTVALAVFTRA +ARADLPRVDAAIAHAARYAAD-- +>[subseq from] Putative beta-lactamase n=1 Tax=Selenomonas ruminantium subsp. lactilytica (strain NBRC 103574 / TAM6421) TaxID=927704 RepID=I0GNU3_SELRL +--ALAEKITALSNADSTRYSLYAAYPQENRAP-YIYQSEPMRSASMIKVFLLANAMEKVR +DGQLSLDMGITLHSGDKVGGAGVLCGYPSGSIPLDKVLRLMITESDNTATNLIIDLL-GM +DDINAYIRRNGYHDTTLARKMMDFAA-VNAGRENYTSVTDLGNLFQKIYHHDCVGYEQDE +IMLSYLKGQTD-RECFPAALP-SAVIAHKTGELG-GLYDDGGIIYHSNRD-MIFVIMTEH +YS-SRYRAIETMKSMAQIAF--- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis X23 TaxID=1200792 RepID=A0A291BUF6_BREBE +--ELEKRLSAIIGQAEGTWGVVVEEQGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE +QGHFRLDDPLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK +AKIDQTMIDLGMRQSCYSRKLMIYPLD--ITENNKITAGNVASMLGQMATGSYLSEHACK +EMIAIMKKQQV-RNGLPSQLPSEWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD +VT--AQSALNTLGLLGRAVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SID10853 TaxID=2706028 RepID=A0A6B2S468_9ACTN +----QRTIRGMFADAGVRGWLHVAELRRPTAYvSVDPDEPVPVGSVYKMPLMVAFCRLAD +SGAVDPRLRVTLEPSDRMPPTGISVLRDAVSMSLRDLVALMMTISDNTAADAVLRRI-GT +AAVDEVCRDLGMRDTTVHGGVATTFAVYDPLSKASATPADMALLLRAIWTGRAASAESCA +FMRGLMGKQPW-THRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELPDGSAYTAVVFTQA +ARADLPRADAVIGAAARVAVE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID5789 TaxID=2690310 RepID=UPI001369803B +--ATAARLGAAFAEAGVTGWLHAVDVDSGAQV-EAGADQAVCTASVHKVCVLVALHEQAA +AGVLDLTEQVECPAEGRTPGPTGLSAMLDPVLSLRDAAFWMMSVSDNTAADLLLRRV-GL +DVVNRTTERLGLTRTRAVYGFGEMLSALDPARTNRSTPRDMTRLLTAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SM1 TaxID=402229 RepID=UPI000CD5B8A6 +----VARIHAAFADAGVTGRLHALDIDSGGQL-DAGADQPVPTASVHKLCVLVALHEQAA +AGLLDLTERVECPPVGRTPPTGVAAMLDAARLSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTARLGLPRTLAVHSFGDLLAALDPARTNRSTPREMTRLLAAVWRDEACTPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPVADTVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0013E360C0 +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECTKDLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Pedobacter ureilyticus TaxID=1393051 RepID=UPI00110D0BF3 +--KLNKMINELAKDFNGDVGIYVKSLKTGKIA-AFNADTIFPTASMIKVPITCGIFDKIE +KGELDYKAQLTYKDSLLYAGEDILGSFKNGEIWLTKVLMLMITTSDNTASLWCQSLAGTG +VAINNLMAQYGLQHTRVNSRTPDRQANQRKYGWGQTTPREMATLLTLIRDGKMISPAASE +RIYRNLIRIYY-DKEALSEIPPYVQVASKSGAVN-ASRSEVVLVNAPHGD-YVFCITTKN +QKDTDNEGEVLVRKLSKMLWNYf +>[subseq from] Beta-lactamase class A n=1 Tax=Actinomadura mexicana TaxID=134959 RepID=A0A238WSY3_9ACTN +----AERIEAAFRSAGVTGFLHVVDIDTGRDV-AVGADEPVVLASVFKVPLLVAFHRLAA +EGVLDPAEQVTLSPDDRTAPTGVSALLDEVRMSLRDLTCLMITVSDNAAADVVMDRV-GL +DAVNATAADLGLRHTVIVGNGRDLHEALDPLRTSRSTPRDMTRLLSMIWRDEAAPPAGSA +AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGARYAVAVFTRS +MLAVLPEADAVIGSAARIAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter phyllosphaerae TaxID=1812349 RepID=A0A4Y8AK18_9SPHI +-qKLTAQLLAATKGFHGDVGIYVQNLKTGKTA-AINADTLFPTASMIKVSILSGLMDKID +KGELQYNQKLVYYDSLLYAGEDILGSFKDKDIQLSKVAMLMITMSDNTASLWLQKLV-GG +DYINNWLDANGFKAMRVNSRIPARRAVWEKYGWGVTTPREMCRLFTMIREGKAVSPAASE +RMSRTLNRIFW-DETALSQIPPYVQTMSKQGAVD-ASRSETVLVNAPHGD-YVFSVITKN +NKTSDNEADVLIKKVSALLWHYf +>[subseq from] Beta lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=D9W717_9ACTN +---ARRTIRGLFADAGVRGWLHVADLRRPEACvAIDPDEPVPVGSVYKVPLMVAFWRLVD +AGTLDPCERMTLGPSDRIPPTGISILRDDITVSLRDLVALMMSVSDNTAADVLLRRV-GT +PAVDEVCRDLGMPDTRIHGGVATTFAVYGPVLKSSATPADMARLLRAIWTGRAASAEACA +FMREAMGRQPW-THRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELADGSAYTAVVFTQA +ARADLPRADAVIGAAARTAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Nocardia alba TaxID=225051 RepID=A0A4R1FZY8_9NOCA +----------------------------AGEV-CVGGRERVVIASVYKLLLLATFLRQVD +HGLIDPAGRLTIDPADCTPPTGLAALHDPVTLSRRDLATSMMTVSDNAAADVLLGEV-GL +AAVGELLRELALTDTRIVGGTADQHRAYDPSYASATTPEEMTRFLWRLWSGDIVSTASTA +FARTVMGKQIW-PHRVAAGFPRGVLVAGKTGTIGV-IRNEVAVIEFPGETPVAVAVFTRA +ARADLPVVDAAIGEAARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Cyanobium gracile (strain ATCC 27147 / PCC 6307) TaxID=292564 RepID=K9PBQ3_CYAGP +----SQQWARLAAQKGLTASGFLLVLDDGRYA-ELQPDLPLSAASSIKVPILLAGLEDLD +RGKLRWNEPMPLTKEVVGGGAGWMANPLGTRFPFFEAATEMIRVSDNTATNLLIRRLGGK +TELNSRFRSLGLTATVVNNWLPDLDGT------NTTSSRDLARSIALVDTGDKLTPRARD +LFREIMGTSRT-NTLIPELLPEGITVYNKTGDIGI-AYSDTALIQMPNGQRAVLAVMVKG +PFND-PRSAELIRAMAGAVTK-- +>[subseq from] Beta-lactamase class A n=2 Tax=Clostridiales TaxID=186802 RepID=A0A2U1CFW4_9FIRM +--ELSAYLAAEIAAFPGKTSLLVADLPTGAVRhAWQPEEPVPSASTIKVPILLAALEEVR +LGRLSLEQRVVLPAAALLPDTEVFDR-GETDCSLWELLYWMTALSDNTATNVILDLL-GL +DAVNRYATRLGLRHTVCRRKMLDAAAA-AAGRDNRTSAADQCRLYRQLCLGRLLTPRLTE +TALDLLRRQRCMDAALR-YLPYPVDFAHKTGELD-GVTHDAGVFFQGSGG-YYLGIFTWE +GPDGDPEQKRYIGRLARAIYETy +>[subseq from] Class A beta-lactamase (Fragment) n=1 Tax=Hymenobacter sp. TaxID=1898978 RepID=A0A519Z910_9BACT +------------------------------------------------------------ +-------------------------------VTVKELLTYMLVVSDNDACDILLKLLGGP +RQVMAYVRHLGVKHLVIKASEAQMGAAWPVQYTNWSYPSAQIELLTIVYRQTALTKPSNE +LLGQLLLATSVGPMRLKGLLPPGTPVAHRTGTSATNATNDVGIIQLPDGRHLAMAVFVSD +SYADLATRELVIAQLAEAAYKEf +>[subseq from] Serine hydrolase n=1 Tax=Planomicrobium sp. CPCC 101110 TaxID=2599619 RepID=A0A5C5UQB6_9BACL +---LKQKIEERLLKIDGI-GSLFIE-TEGQSI-TINPDRKMKAASVIKLPILLEGYRQID +SGIISGTDRISLSKKELVGGSGILAHLESVRLSVHDILMLMTIVSDNTASNLAIKHL-GM +ENINGLTAMLGCTNTVLGRQFMDLEAA-EKGLDNFTSARDMVLCLKEADTGKTLAKKSRQ +QVIHTLKQQQL-TANLHGRIDSEVSIASKSGSLS-GVVNDVGMIELSGQK-VYVAVLLGD +LP-DNHTGQEIIADIGWYIHE-- +>[subseq from] Uncharacterized protein n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A644ZGV3_9ZZZZ +-qALDAYLNSEIRKFPGKSSVLLADVDTGEIHfATNPHSPVVATSTIKVPILLSALDQVK +QKKLSLAQPIAVPDDRILPDTQVFEL-GQSDYSLWELLYWMITMSDNTATNIILDLL-GM +ETVNEYCNSLELAHTRVARKMLDFDAA-AEGKENFTSAYDQYRMYCHLCHGRLFSRQLTK +VALDILARQRSTD-QFLRYIPRTVTVAHKTGTLD-GISHDSGVFFLPHMRCYLGVFTWDG +PSEGNPSQKQFVGRLARAVYTTf +>[subseq from] Serine hydrolase n=1 Tax=Chitinophaga barathri TaxID=1647451 RepID=A0A3N4MG29_9BACT +-rKLEKALAAMVGEFKGTAGVYVLHVPSGRFA-AVNADTIFPTASIVKVPLLVGLFDKID +KGEVKWNQPLVYHDSIKYGGSGLMQFFKDSSTEVSVLAALMMAYSDNTTSLWNQALAGGG +AQVNILLEKYGLKDTRVNSRTPGREEDRKVFGWGQTTPREMSTLLLKIRNGEVVSKGASE +KMYRLMTKGYY-DNQAVSEVPPYVQVAAKTGSVNE-SRSELALVNAPHGD-YVFYVGTKG +IKEEENEAVQLIRKVSAYLWAYy +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. LM3 TaxID=1938608 RepID=A0A1T1BE52_9DEIO +-------------GFAGTVGLWVGTPQGEALA-TLNVDRVFPAASTIKVPLLVMALQAAQ +RGDLSLDGRVTLSAQDRVPGAGVLHELGAGLLSWQDVLTLMIIVSDNTATNLTIGWL-GV +GAVNGWLGAHGLNGTRLVGKLDQRNEAQRRGERNATTAADQARLLRLLLGGDLLDPPHTA +LALSILGRQQY-RDLIGRGVPAYYRVASKSGELT-GVHHDVGVIFTP--RPLVVALLSEG +GQREHPENRDVTALA-------- +>[subseq from] Uncharacterized protein n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A6B8Q6Z5_LACPN +--QIRNDISSTVGAISGTNSVYVSPVNSKQAV--LVKDGSQRSASSIKIFIMVTAYAMAK +EGVFNLTDTHTVTDSEKVGGTGVIQNMDAGTLSYQEIIEHMIDDSDNTAANIMIEKLGGF +DLINNKISNMGATDTKLRRKMMDTK-ALDDGKDNTTSAHDMGMTLKKIYNHQLVSRQADE +AMLTILAKNQN-RTKLPKDLPSSATVYNKTGEYDYGVQNDAEIVKNSHGA-FVAVVLSED +GDQ--NDQIDAMNRLGSLLYQ-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3L7YIJ2_9CHLR +---LAGEVVSVLRGRDESVSIAAVHLLDGTGV-ALNADDVVPPASLFKLNILAETYRQIE +RNRVKLAQMITILPEDAAPGAGILQDRIGEAVSVGEALSLMIGISDNTAAFALLRTI-SS +RKLNECTRALGMLRTWFYVDER----------PDETSAGDVVTILRAIIDGTIASPRGTD +QMLELMTQVQS-SAWIRSGLPPGTRLAHKSGQLE-GIRNDAGIVFGPTG-PYALAVLTHD +LY-DPAVGEQIITAVTRVVHRYf +>[subseq from] serine hydrolase n=1 Tax=Lachnospiraceae TaxID=186803 RepID=UPI00040B41F9 +------EIIEKLERLPGKISFLYENLETGDGF-SYHQQEPMMAASVIKLFVMAAAFEKEK +RGTFSMDEMFSVKKEDRVPCGALTYLHDGILVTGMDLVTLMIIFSDNTATNVLIDIL-GM +EEINEIIRGLGFRQTLLQRKMYDMERS-GRGIQNYITAHETGRLLKMMYNGVLIDRQSSK +TMISILKNQQL-CSKIPFYLQESPEIAHKTGEDT-GITHDVGIVYGK--EPFL-VCFCGN +ET-DTPAFERVMAEVSLDLY--- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CNZ279 TaxID=2035251 RepID=A0A2G7EJ66_9ACTN +haRARDRIRAAFAEAGVTGWLHAVDIDSGAQV-DAGADHPVVTASVHKVCVLVALHQQAE +KGRLELTEQTECPPDGRTPGPTGLSAMLDPAVSLRDAAYLMMAVSDNTAADLLLHRV-GL +EAVNATTRRLGLTRTHAVQTFGEFVAALDPASTNRSTPRDMTRLLGAVWRDEACAPQHSA +AIRRLLSLQVW-PHRLASGFPDDVHVAGKTGSAPT-LRNEVGVVEYPDRGRYAVAVFTRA +ASPALPAADAVIGTAAHLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Terrimonas sp. YJ03 TaxID=1104781 RepID=UPI001264118C +-kKLQSRIADAVSGFNGTVGIYVHDLKHNKVA-YFNADTVFPTASIVKIPILLGIMQKIE +TGELNYHQRLMYRDSLFYDGDDILSRFKDSAIELSKVMMLMITISDNCASLWLQALAGSG +TRINEIVDSLGYTSTRVNSRTPGREENRRIYGWGQSSPREIAGIMEKIVRGEIYSKAASD +RMLRLLGRQYW-DEQALSQIPAGVFAADKTGAVD-GSRNEVLYVNGKKN-PYIFSIFTKN +NKNENNEAWMMTKKISALLWAYy +>[subseq from] Serine hydrolase n=2 Tax=Streptomyces sp. A0642 TaxID=2563100 RepID=A0A4S2UZY0_9ACTN +---------------GVRGWLHVAELHPSARV-TVDPDEQLPMGSVYKIPVMVAFCRLVE +AGRIDPVRRVTLEPGERVPPTGISLLSDAVTMSLRDMVVLMMTISDNTSADAVLRAV-GP +DVVDAVCRSLGMPDTRIHGGVVNTFSVYDPAYKASTTPSDMARLLRAIWTGQAASEEHCA +FMRGVMRQQPW-AHRLGSGFPDDVTVYGKTGTFGS-LRHEAGVVELADGTTYTAVVFTQA +ARSDLPRADAVIGAAARAAVE-- +>[subseq from] ClassA_beta_lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WGG9_9BACT +------------------------------------------------------------ +--------------------------------TVAELLESSIVRSDNTSTDKLLPLIGGP +AGVTDRMRTLGVANINIKYSSREFAA--HRDKPNTGTASDLAKLLAKLQKGELLQPAQLS +LLLGFMEKARTGERRIRANLPAGTQVAEKTGTGD-GTTNDVGLITLPDGGHLAIAVLITR +SKVSPEAQEKVIAELARAAYDA- +>[subseq from] zinc-ribbon domain-containing protein n=2 Tax=Lactobacillus brevis TaxID=1580 RepID=UPI00111BC2B6 +----KKDIGVTVGAIGGTNSVYVSPVNSEQSV-VV-NNGSQRSASSIKIYIMVTAYAMAK +EGVFNLNDTHTLTNDEKVGGTGVIQNMRAGTLSYREIIEYMIDDSDNTGANIMIDKLGGF +QLINNKIKSMGATDTKLRRKMLDTK-ALDNGRDNTTSARDMGTTLKMIYNHHLVSREADD +EMLAILRKNQN-RTKLPNQLPSTATVYNKTGEYDYGVQNDAEIVRNSQGA-FVAVVLSED +GEETDQ----------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Cytophagales bacterium TFI 002 TaxID=1945892 RepID=A0A286IKF4_9BACT +-----NSLDSYFKELDPEIGVSMQLMNKEGEV-LFAKDDTVPAASTIKVPILIAYYVALE +KRLFKAKAKYELNEEVKVGGSGIQYANAMTEYSLDQLALEMIRVSDNTATNIMIDKI-GM +ENINKMSAFYGLNKTMLRRKMMDFEAV-LEGRQNTTTASEMNQLLLKMLNGELVKPKYQK +AMIKKLLACED-YTTFAAKLY-GVPIAHKTGTLDY-MRADVGIIYG--KEPLILSVFVQN +FE-SHMQAQTILADIAEIVYFQf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. KO7888 TaxID=2602737 RepID=UPI0013F612EE +--ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GVRADQPVCTASVHKLCVLVTLHELAA +AGALDLTEQVECPPDGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL +DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEAGPPECGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A6B1KG54_9ACTN +----LARIHAAFADAGVTGRLHAVDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA +AGLLDLTEQVECPPDGRTAPTGIAAMLDGARLSLRDLAYLMMSVSDNAAADLLLARV-GL +DAVNRTTARLGLTRTYAVHTFGELLAALDPARTNHSTPRDMTRLLAAVWRDEACTPEHGA +AIRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT +ARTSQPAADAVIGTAARLAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga dinghuensis TaxID=1539050 RepID=A0A327W0I1_9BACT +-kKLTATLQQLLKDFHGQAGIYVHHLPSGKEV-CINADTIFPTASMIKTTIQVGIFNKIA +KGELDYHQQLVYRDSLLYPGLDILGSFKDSQIDLDKVVMLMLTMSDNTASLWLQSLAGGG +TTINAWLESNGFKVLRVNSRTAGREANRKEFGWGQTSPREMARLMEMIYKGEVIDPASSE +RMYRNLTRNYWDA-QGILQVPENIRTASKNGAVDE-SRSEVIMVNAPHGD-YVYCIATKN +NANKDNEAWQLLRKVGYAIWQHy +>[subseq from] Serine hydrolase n=1 Tax=Paraflavitalea soli TaxID=2315862 RepID=A0A3B7MUE3_9BACT +-rKLQQKIDELVKSQRGVAGIYVKNLRTGKVA-EYQADTIFPTASIVKVPILVGIMDKIE +KGELQYHQNLEYKDSLLYAGEDILGSFKSGEIELSKVMMLMLTMSDNTASLWLQSLAGTG +ARINQLLDSLGLQYTRVNSRTPGREDNRKQFGWGQTTPREMTTLMEKIYRGEVISHKASE +RMLRVLGRNYHDPNGI-SQVPPYIFVASKTGEVNQ-SRNETILVMAPHGA-YAYTINTKN +LEEPSNEGWVLCRKLAALLWQYy +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. Tu 3180 TaxID=2682611 RepID=UPI00135CA250 +-----ARIHAAFADAGVTGRLHAVGIDSGAQL-DAGADRPVCTASVHKLCLLVTLHEHAA +AGRLDLTEQVECPPEGRAAPTGLAAMLDAARLSLRDLAFLMITVSDNTAADLLLRRV-GL +DAVNATTARLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA +AMRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 137-3 TaxID=2486021 RepID=UPI000F776524 +---------QAMGQLKGHNSVAIATSFSDDHY-QWHNQ-AQRAASDIKVFILATVYHQVD +QGKYQLSGHYTLRDADKVGGTGSLQGMAAGTVTNQQLLHYMMTVSDNTATNITLRQVGGL +GVVNRYARDLGAKDTHVVRKMMDQK-ALDAGKDNLTSVADLSMVLMKLWRHQLISTSADT +AMLKLMSENTN-HSKLPKDVPTDRTVYNKTGEFDYGVENDAAIFAK-GGKAVVVVAMSEG +GQQQVPAMNR------------- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI000D0EDF4A +--ELEKRLSAIIGQAEGTWGVVVEEQGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE +HGHFRLDDQLVLRQEDLVGGSGILYALSPGLLAIRDLVTLMIIQSDNTATNMLIDLV-GK +AQIEQTMIDLGMRQSYYSRKLMIYPLD--ITENNKITAGDIASMLGQIATGSYLSQRACK +EMIAIMKKQQV-RNGLPSQLPNQWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD +VT--AQSALNTLGLLGRAVYDY- +>[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. G0240 TaxID=2487066 RepID=A0A3N0WG60_9FLAO +---ITTDINKLIAHKKLDIGISIRNTSGDEIV-SVNSKKKYRLYSVSKFFLALYILNQVD +KGKLDLNQIITFSKKDLKPYSPLRDSIPQGALSLKKTIKYLVEESDNNVFNKLADISGGL +NHLNVFVYNTFRASKNEFFEMYDYSSSKSDFEANSITPNLATEILYQLEKKEILSNNSYR +LLKKYMEHSAI-DTRIQGIIKNDTKSFHKAGTSDREACNDIGIVNLKNGTSFMIGVFISD +SKEDDKTNDTLIAQITEIAYK-- +>[subseq from] Class A beta-lactamase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A1Y4WV00_BREBE +--ELEKRLSAIIGQAEGTWGVVVEEQGKGTRF-VHVPDELFIAESVIKVPIMAAVFAARE +QGHFRMDDQLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNILIDLV-GK +DQIDQAMIDLGMHQSCYSRKLMIYPLD--IRENNRITAGDVASMLGHLATGSFLSQRACK +EMIAIMKKQQV-RNGLPSQLPPGWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD +VT--AQSALNTLGLLGRAVYDY- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI000686D4DF +------------ADAGVTGWLHAVDVDSGAQV-GVRADQPVCTASVHKLCLLVTLHELAA +AGALDLTEQVECPPDGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL +DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEAAPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Aggregicoccus sp. 17bor-14 TaxID=2583808 RepID=UPI00129CB17F +--ALAERVRGIDLAHRGALQVWVQDVASGESY-GYDAEAPAYLSSTLKLVVALAVLREVD +AGALSLDEPLRLEAQDVRDGVGLLGPDVGTERSVGQLLELMLVRSDNTAADRLITRV-GE +DRLDSEVACRGLHFGPLRSLLTERQQAFYATGVNTAPLREVGGLLAQVARCEGLSAGSCA +RMQTLMRACRTGAARVRAGLPAQVAWAHKTGTQFQ-RACDVGFFTLAPGRSVVVAACARD +FD-QVPEAEAAFREVGAAVWS-- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus brevis TaxID=1580 RepID=UPI000B34D39B +----KKDIGVTVGAIGGTNSVYVSPVNSEQSV-VVNK-GSQRSASSIKIYIMVTAYAMAK +EGVFNLNDTHTLTNDEKVGGTGVIQNMRAGTLSYREIIEYMIDDSDNTGANIMIDKLGGF +QLINNKIKSMGATDTKLRRKMLDTK-ALDNGRDNTTSARDMGTTLKMIYNHHLVSREADD +EMLAILRKNQN-RTKLPNQLPSTATVYNKTGEYDYGVQNDAEIVRNSQGA-FVAVVLSED +GEKT--DQLAAMNKLGL------ +>[subseq from] VanY domain-containing protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535YIK3_9CHLR +--SLQDAVKAAVGRHQGTIGVVVTRIDSGQAF-SFNADRRFTSASLYKLFVLDAAEAAIE +AGTLDPSETLTVTSA-MAANDPYADLQVGTRTSVDCALQTMVEMSGNSAADLLLRRL-GM +STITSRMRALALNHSEIND-----NGA-------FTSPGDVAHLLASVARGEAVNVAASQ +RMLDLLGAQQH-NDRLPAPLPLNVRVAHKTGELP-GLRHDAGIVFAPSGK-YVLVAMVDD +AP-SESEARAAIVDISRSVYA-- +>[subseq from] serine hydrolase n=1 Tax=Cyanobium gracile TaxID=59930 RepID=UPI00030F1BED +----SQQWARLAAQKGLTASGFLLVLDDGRYA-ELQPDLPLSAASSIKVPILLAGLEDLD +RGKLRWNEPMPLTKEVVGGGAGWMANPLGTRFPFFEAATEMIRVSDNTATNLLIRRLGGK +TELNSRFRSLGLTATVVNNWLPDLDGT------NTTSSRDLARSIALVDTGDKLTPRARD +LFREIMGTSRT-NTLIPELLPEGITVYNKTGDIGI-AYSDTALIQMPNGQRAVLAVMVKG +PFND-PRSAELIRAMAGAVTK-- +>[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas sp. GW2 TaxID=1211114 RepID=UPI0005852AFE +------------------------------------------------------------ +----------------------------------------------------------GE +PRLQALADALGVPRAELDTTLEQVFEDYYARGLNSATLPAYGRLLERLASGELLSPRSTA +LLLGHMRAISTGSRRIQAGLPAGADFAQKTGTQQQ-RACNVGLLDPAGRDGATVVVACAE +RFGELEQAEHAFQALGRALA--- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Balneola sp. TaxID=2024824 RepID=A0A3D2IC62_9BACT +----QVKILNRLVGIEGDFAISYKDINDAEKHiLINADERFHAASTMKTPVLIELYKRAE +NTDLNLEDSILIKNESIVDGSLFTYLNLNKNTTFYALAYEMITRSSNLATNILIDYL-GA +ENITNTMRDLGADSINVLRGVEDLKA-YRQGLSNSTTARDLLVIFDHLSTGTLISEKANV +EMLKILKDQVY-NDMISAKLPKGTPVAHKTGWITN-VHHDSGIVFTGNNEGYILVFLSKN +APDRD------------------ +>[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas sp. J31 TaxID=935851 RepID=UPI00048F8CB8 +------------------------------------------------------------ +----------------------------------------------------------GE +PRLQALADALGVPRAELDTTLEQVFEDYYARGLNSATLPAYGRLLERLASGELLSPRSTA +LLLGHMRAISTGSRRIQAGLPAGADFAQKTGTQQQ-RACNVGLLDPAGRDGATVVVACAE +RFGELEQAEHAFQALGRALA--- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. UNC363MFTsu5.1 TaxID=1449069 RepID=UPI000483D817 +------------------------RVDDGDAV-SVEADDLVVTASVYKLPLLVALCREFD +TGALSPTATVRVNPADCTPPTGVSIFRDPVVMSWRDLALSMMTVSDNAAADLILGSV-GL +DGIDRVLTELGLRRTRIIGGTADVHRAYDPAFTSATTPREMTSLLDAIWTGRAVSAAQTE +FIREVMAGQIW-PHRIRSGFPAGVTVAGKTGTIG-AIRNEVAVVGFPGETPVAVAVFTRA +ARADLPVVDQAIGRAAHIAVT-- +>[subseq from] Serine hydrolase n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A3R9T0D6_9ACTN +----AGRLHAAFADAGVTGLLHAVDIDSGAQV-GAGADQPVCTASVHKVCVLVTLHELAA +AGEIDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAALLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGEMLAALDPARTNRSTPRDMTRLLTALWRDEACPPQYGA +AMRRVMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT +ANATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase (Fragment) n=2 Tax=Subtercola sp. Z020 TaxID=2080582 RepID=A0A2S5VZK4_9MICO +---ISAELASLESTSAARIGVSAVDTATGRTI-AYRADERFGYASTIKVFAASLLLQTTP +--PEDRARLANWTQSDVDAHSPATGEHVADGLSLAQLAEAAVRQSDNTALNVLLANLGGP +QALDAALTQLGDDTSDVVDVEPALNTVEPGSTANTTTPAAFTADLRALLN---------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. H3C3 TaxID=2530368 RepID=A0A4R5BUM5_9ACTN +------RIEAAFRDAGVTGHLHAVDVDTGREV-AVRAEEPVVLASVFKVPLLVAFHRQAA +AGTLDPTERVTLRPQDRTSGPTGLSALLDEVMSLRDLACLMITVSDNASADALLERV-GL +DAVNATAAALGLPGTVVEGGGRDLFDALDPALTSRSTPRDMTRLLGLIWRDEAAPPPECA +AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-IRNEVGVVEYPDGGRYAVAVFTRS +PLAVLPEADAVIGAAARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Nibribacter sp. BT10 TaxID=2698458 RepID=UPI001366EB34 +-qKLTQKLEALTKGFEGEVGIYVKHLKTGKTV-AINADTLFPTASMIKVPIMVGVFNKIE +RGELDPKAILQYRDSLYYAGEDIVGNFKDSSVALSKVQMLSITTSDNTGSLWLQQLAGTG +TAINQWLESNGFVHTRMNSRTPNRRPNWERYGWGQTTPREMATLLTTIREGKAVSPAASE +RMYRNLGRIYY-DSEALSQIPPYVHTASKSGAVNQ-SKSEVVLVNAPHGD-YVFCIITKN +QKDEDNAGSVLIRNVSKILWQHf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. NEAU-D10 TaxID=2293571 RepID=A0A371Q1R5_9ACTN +--DTAARIHAAFAEAGGTGWLHALDIDSGAQI-DAGADQPVCTASVHKLCLLVTLHELAA +SGSLDLGEQIECPPAGRTAGPTGLAAMLDPVISVRDVAYLMMAVSDNAAADLLLRHV-GL +DAVNRAMTRLGLTRTHAVHTFGELFAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA +AIRRILGLQVW-PHRMASGFPDDVHVAGKTGTLPT-VRNEVGVIEYPDGGRYAVAVFTRT +ANATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. CYP1-5 TaxID=2604572 RepID=A0A5D3FM37_9ACTN +---ITERIEDEFKAAGVTGWLHAVDVDTGREV-SVRADEPVVLASVFKVPLLVAFHRQAA +SGVLDPSEQVALRAEDRTAPTGVSGMLDDVRMSLRDLAFLMITVSDNAAADVVLDRV-GR +DAVNATAEALGLPGTVVEVSGRELHGVLDPLRTSRSTPREMTRLLSLIWRDEAASPEGCA +AMRRLFGLQVW-PHRLSSGFPDDVLVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +LLAVLPQADAVIGTAARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Brevibacillus porteri TaxID=2126350 RepID=UPI000D0E606B +--ELEIRLSAIIGQAEGTWGVVVEEQGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE +QGHFRLDDPLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK +AKIDQTMIDLGMRQSCYSRKLMIYPLD--ITENNKITAGDVASMLGQIATGSYLSERACK +EMIAIMKKQQV-RNGLPSQLPNEWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD +VT--AQSALNTLGLLGRAVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. CZ-2 TaxID=2557994 RepID=A0A4P7DYC5_9SPHI +-kKLTAKIQQEINGFRGDIGIYVKNLKSKKEV-RISSDSIFPTASIVKVPLLVGIFQKID +ANEVQLDQKFIYSDKRTYGGSGLMQFYKDSATDLSTMISLMLTYSDNVTSIWIQELAGGG +QTINPLMDNLGLKNTKVNSRTAGREDIWKKYGWGQTTPYEIAHLFELIRDGKVISEKHSD +KMYRFLKNQFY-NERSLSQIPAIYATISKTGSVND-ARGEVVLVNAPHGD-IVFSILTKN +NKTKDNEAENLTRRIAKIIWDHf +>[subseq from] serine hydrolase n=1 Tax=Pseudoclavibacter caeni TaxID=908846 RepID=UPI0013012D89 +-------------------------------------GGRVAAASTIKVALAAYVLDGVD +RGSWTLQTPVTVPADDVVGGSGTLGGQAAGRYPLEQLLRLMITVSDNTAANALIDLVGGF +DPVNAWLVEHGFDELHLGRKMILPHAA---DAENWISADQAVRLLAAIHDHTLVSVESSE +RLIDLMRDQTV-RTKLGAVIPHD-LLADKTGENT-GVSHDIGYLLVPGRT-VAIAVLTGY +DGAGADAANSTVQRAGAAVL--- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0005C729BE +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A2C1I0R7_BACME +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNKVGGAGILRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. IHB B 7164 TaxID=1827146 RepID=UPI0007CDABCE +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGSDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus enclensis TaxID=1049584 RepID=A0A1C4FVS2_9NOCA +--SAQQVIAAVLAEAKTDAYVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Candidatus Amulumruptor caecigallinarius TaxID=2109911 RepID=A0A4Q0U8U3_9BACT +---LKERIDSIIKEKPGKFGVALI-VDNRDTV-TVNNTDDYPLMSMFKLHEALGVCHVMD +SLGRGLDSVMVISREHLDPYSPMLKEYDMPELSVGRLIDYILVDSDNNASNWLFDSIVPV +SYVNSYIGTIPEQSFEIVWRESDMAAEHSRAYDNRSTPLAYASLVNRVFTDSIVSRDKQE +HIKSAMLRCDTGMSRLAAPLEEGVTFGHRTGSGYVNAVNDGGYVTLPSGKSYAIAVLVKD +YAGPQEDAEAVMAAISKAVYD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000476C1CC +------------------NGLIRIHIEGKESI-RINSFIQQRAASTIKLLLAIEAFRQID +AGILALTSVIQRMEKNTVGGAGVLKALPQLTIKVEELLTLMIIVSDNTATNELITLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRK +KIMRMLEMQQF-QHKLPACIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=UPI00131F6ACD +---LEYKIREIMVRSKGRVSVAVEL--PYHSF-HIDGDRSYSAASLIKIPILLEAFRQAQ +EGDIFLSDMVTIPKEGRVGGAGVLVSLSDQLLTIEDLVTLMIIVSDNTATNFLIDRL-GS +NAIQELCHSLKLKHTRFLRKMMDFE-ALEQGVNNYTSALDIITCLKVLDIGKEYCQTSRW +KMLHILGQQQF-DTKLPSRMDEAVYIGNKTGELS-GVEHDCAIIKYREKT-AYIAVLIDG +LGET-ESGKDTIAQIGKLIYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536C911_9CHLR +--ELVQHLDQLVSSFPGGAGLWIADPNAAKPLySHDADEPVITASLYKLAVLAEAERRVD +AGQLHYGDVITIESEDITEDGSF--EVAGTELTLDQALEAMITISDNGAALALWHVL-GA +DNINATLRNVGINDFHVFVA--------WGEDANVATPRAIGTLLTLLAKRQLISAAASD +RMLARLERQQI-NDRLPAELPEGVVVAHKTGNLP-GLTHDAGIIYTPSGP-RVVVAMTWD +AY--DADAYAFIANVGSIVYS-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus acanthi TaxID=2171554 RepID=UPI000D3EBCF3 +--ELTARLNSEIKNCPGKMSVMLEV---GQHCfQWDPHRKVPSASLIKLPILLEGFRQIE +NGTLNLYDAIQIQEYQKVEGAGVIHKLSNAKLTVQDLLTLMIIVSDNTATNVLIDLL-GM +EKINSFIKEQGCNSTELNRKMMDFDSII-KGINNWTTASEMVLMLKEIDIGLGYSSNSKE +LMKGILQNQQF-LDKLPLDLEDGW-IGNKTGELS-GVEHDCAIMKKGNKS-AYITVLCDS +LP-SKGVGKIAIAKIGSLVWEY- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0012939A40 +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILALTSVIQRTEKNAVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGVDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLKMQQF-QHKLPARIGSAFQAVNKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2D8LF37_9CHLR +--KLVKSINTQVENFNGVAGVSIKDLTTGWYY-GINDEMIFPTASSIKIPILLKLIESSE +ASKLNLLKNIEITEEMKSRGSGVIHKMNGTILTVENLAILMINLSDNTATNLCIDIA-GQ +DEVNKMLEDYEFVSMRLNRKMQDYT-AIKEGRENLSSVKEMNLILEMLDSSRAIKPDVAK +KVLNILSLNKS--TPISQPLPENIIVAGKTGGMP-GVRCETAIIYLTNRK-YILTVMTSH +AGNGSSSSNQNIG---------- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus enclensis TaxID=1049584 RepID=A0A2A5JG58_9NOCA +--SAQQEIAAVLAEAKTDAYVHERDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. p1417 TaxID=2681492 RepID=UPI0012F672A2 +-----TRLKEAFAEAGVTGRLHALDIDSGAEL-GTGADHPVVTASVHKLCVLITLYEQAA +AGLLDLTEQVECPPDGRASGPTGLSAMLDPVMSLRDAAYLMIAVSDNTAAELCLSRV-GL +DAVNATTARLGLTRTRALHTFRAMFEALDPARSNHSTARDMTRLLRALWRDEACTPEHGA +AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA +ARATLPPADAVIGTTARIAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A645BKY1_9ZZZZ +------KIGAMRFSLPGKSAVAAVNLVTGDAF-SWNGDEIFPSASIIKLPILCTAYAMAE +SGELSLSDRIEVTDAAKTGGDGVMRLMQPGLPTLHDLMTLMIILSDNMATNMVVDAV-TP +QRIHEFLESRGLTRIRWRRKMMDAA-AMAAGIENEAAAGDVTELLKGLAMGTLLSPAHCR +DALDILSRQQI-NHKLPRRLWEEIKIAHKTGDIP-GLEHDAGVFTGPGF-SFVLTVMTLG +PREPQQKQWDFIGAVAEEFVRYw +>[subseq from] Serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A6B3R733_BACME +------------------NGLIRIHIEGKESI-QVNSFIQQRAASTIKLLLAIEAFRQID +AGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Symbiobacterium thermophilum TaxID=2734 RepID=UPI00130DCC32 +---VVRRIERLTRWAPGVVSVWYYDLSTHETF-GVRADEVYTAASTVKVLIANYLYHLAA +TGQVSLDEPLAIRAVDWKDGSGILNGVPDGTLPLREVARLMLVHSDNTAANALMRRL-GV +QPMVQYYRSLGIR-----YGTPRMHTPGELWEGNRIAPEDLGIVLRNIWEAARRSPEPWE +ELLGFMRESRS-KGRIPAGLPSHVPMANKTGSKGT-SFHDAALVL--DRRPYVLVVMTQG +MT--ARQASHYIAAVSREVWE-- +>[subseq from] Beta-lactamase, putative n=2 Tax=Deinococcus radiodurans TaxID=1299 RepID=Q9RX82_DEIRA +-------------GYAGEVGLLVTDFAGRELY-AQAADAVFPAASTIKVPLLLFALEQAG +RGDLDLIERVTLRAEDRVPGAGVLHELGLGLLTWQDVLTLMIVVSDNTATNLLIERL-GQ +DHFNLWLTARGLNSTRLIGPLERQNEAQRRGERNRTTARDQVALLLSLLRGDGLTPQMQH +LALDILSRQHL-RDLIGRGVPAGYRVASKSGELR-GVHHDVGLLWAP--RPLVVALLSQG +GEDPR------------------ +>[subseq from] serine hydrolase n=1 Tax=Acidobacterium ailaaui TaxID=1382359 RepID=UPI000678C694 +-tALEAQLRGLTALHRGKVAIFAKDLNSGRTV-AIQADTPVPTASVIKLTVLFEALKQVQ +AGKAHFEDRLRLTKDNQVEGSGVLSFFDTPQLTLKDVLTMMIIVSDNTATNMAIDKL-GL +KKIDDRIQWLGLKDTWLYRKVSKPASDQKQFGLGKTTAREMAAVMERFATGETAPPTKDQ +QVAMHMLRNQFYRNSIPRYLEGESKIANKTGALDH-VRNDVGVVDAKNG-PVIISEFTWD +NQTPDNSAEVLMAKAAKIIVDRw +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. BS56D TaxID=2055944 RepID=A0A4R0R5S0_9SYNE +--ALSQRWQELAAQKDLQVSAFLLLLDDGRYA-QLNPDTALPAASSIKTPILLVALELLD +AGTLSWNEPLTLTKTTVGGGAGWMASPIGTRFPTHEVATEMIRVSDNSATNLLIERVGGK +EELNARFNALGLSATAVNNWLPDLEGT------NTTSARDLARSIALVDTGETLGPRSRD +LFREVMGTSRT-NRLLPGGLLKGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFVVKG +PF-NDPRSTELIREMAAAM---- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A231RCC0_9BACI +---LEYKIREIMVRSKGRVSVAVEL--PYHSF-HIDGDRSYSAASLIKIPILLEAFRQAQ +EGDIFLSDMVTIPKEGRVGGAGVLVSLSDQLLTIEDLVTLMIIVSDNTATNFLIDRL-GS +NAIQELCHSLKLKHTRFLRKMMDFE-ALEQGVNNYTSALDIITCLKVLDIGKEYCQTSRG +KMLHILGQQQF-DTKLPSRMDEAVYIGNKTGELP-GVEHDCAIIKYREKT-AYIAVLIDG +LGET-ESGKDTIAQIGKLIYD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=UPI000551775D +---LEYKIREIMVRSKGRVSVAVEL--PYHSF-HIDGDRSYSAASLIKIPILLEAFRQAQ +EGDIFLSDMVTIPKEGRVGGAGVLVSLSDQLLTIEDLVTLMIIVSDNTATNFLIDRL-GS +NAIQELCHSLKLKHTRFLRKMMDFE-ALEQGVNNYTSALDIITCLKVLDIGKEYCQTSRG +KMLHILGQQQF-DTKLPSRMDEAVYIGNKTGELP-GVEHDCAIIKYREKT-AYIAVLIDG +LGET-ESGKDTIAQIGKLIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A2E5I681_9BACT +---------------AGEIAVAMSTLDGDTYF-FYKEKKVFHAASTMKTAVMLELYRMRD +RSELSLKDSLLVVNQSIVDGSTYSMARLGEKMSLKDLNEAMITTSSNLATNILLNMV-KP +EQVMKTVSEVGAEGVLVLRGLEDLK-AYERGLSNRTDAHGMMMLMRAVVESPVVSDDSRD +AMLRILGRQEF-NEMIPVGLPAGTEVAHKTGRITS-ICHDAAIVFPPLQEPFILVILTRG +FEN-HAQATAAGVAVTKSVYSYy +>[subseq from] Serine hydrolase n=1 Tax=Lacrimispora algidixylanolytica TaxID=94868 RepID=A0A419T6S4_9FIRM +-------------PLPGKISFYFENLDTGESI-GYREHETMMAASVIKLFVMVSVFEGVE +RNSFPLDKMFEIKREECVPCGALTYLHEQIQVTLMDLVTLMIIFSDNTATNVLIDFI-GF +DVINRTIVELGFERTVLNRKMFDLVSS-KLGIQNYITAGEIGKLLKMMFEGTLVSRRASD +TMLSIMKNQQL-AGKIPFYLKERLEIAHKTGEDI-GISHDVGIIYGK--VPFIVC-FCGN +ET-DTPRLERLMADISLELYQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium wenxiniae TaxID=683125 RepID=A0A1I6Q2R2_9SPHI +--KLENLLLEQVKDFQGDIGIYVYHSKKNTSV-AINADTIYPTASIVKVPILVGVFNKIN +QGELKLSDSYRYDAKRAYGGSGLMQFYKDSATDLSTMVSLMLTYSDNVTSIWCQELSGGG +ATINQLMDELGLPNTKVNSRTEGREEIWKKYGWGQTTPREIVELMRLIREGKALNPRLSD +KMYRYLKNQFY-NGRSLSQIPAHIATASKTGSVDD-ARGEVVVVHAPSGD-YMFSVLTKN +NKTDTNEAEELTRKISHLLWDYf +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus agglutinans TaxID=1644129 RepID=A0A438BE72_9NOCA +-------FEGLFADAGVRGWVHAVPVAGPDTEaGRDPDTPVVMASVYKLPVMVTFCRSVD +AGHLDPTEQVTLAPENRTPPTGVSQFLDPVRISLRDAVRSMMAVSDNAAADEVLRRV-GV +DRVNETMRTLGLGSTRVLGGTADTLRGYDPVLSSATTPRDMTTLLSAVWSGAAASPEQTA +FMRTVMSSQVF-TARLRSGFPGDVVVAGKTGTLG-AIRNEVGVIEFPDGDAFAVAVFTRA +ARADLPSADAAIGRAARAAIA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. T12 TaxID=477697 RepID=A0A560WEN1_9ACTN +----VARIHAALADAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHERAA +RGELDLTEQMETVPGDRTTPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLSRV-GL +DAVNAATARLGLTRTLAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEAGLPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase n=2 Tax=Lacrimispora celerecrescens TaxID=29354 RepID=A0A084JR07_9FIRM +------EIIEKLEQLPGRISFLYENLKTGDGF-AYHEQEPMMAASVIKLFIMAAAFEKSK +KGTFQMEELFAVKKEDCVPCGALTYLHDGILVTGMDLVTLMIIFSDNTATNVLIDIL-GM +EEINETIQGLGFERTILQRKMYDMVRS-AQGIQNYITAYETGRLLKMMYDGTLIDSQSSD +TMISILKNQQL-CSKIPFYLQDSPEIAHKTGEDT-GITHDVGIVYGK--EPFL-VCFCGN +ET-DTPAFERVMAEIS------- +>[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2E0BAN4_9BACT +--DLEERILKILKTEKGDFAIAFKNLSDGKSI-LINENEEFHAASTMKTPVMIEVFKKAQ +KGIISLDDSIKIKNESIADGSTFKYDKIGSYLSLRELVFDMITISSNFATNLVIDYI-GX +XDINNTMRDLGAKNINVLRGVEXIXA-FXQGMNXTTTALDLLKIYEXLAVGNVINSEXSK +EMVXXXKKQKY-DDIIPKYLPKSIEVAHKDGWIX-GVRHDSGIVFLXDNTXYXLVLLSKN +LE-DEIKGADLLAKVSLEIYN-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces capillispiralis TaxID=68182 RepID=A0A561TGU3_9ACTN +----LARIHAAFADAGVTGWLHALDIDSGAQL-DAGADQPVCTASVHKLCVLVALHEQAA +AGMLDLTEQVECPPAGRTTPTGVAAMLDAARLSLRDLAYLMMAVSDNAAADLLLRRV-GL +DAVNATTTRLGLTRTRAVHSFGQMLAALDPARTNRSTPRDMTRLLGAVWRDEAGTPEHGG +AMRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AQATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Cyanobium sp. CACIAM 14 TaxID=1496688 RepID=A0A081GJ59_9CYAN +--------SRLAAQKDLTASGFLLVLDDGRFA-QMQPDRPLPAASSIKVPILLASLEDLD +EGKLRWNEPMPLTKEVVGGGAGWMANPLGTRFPFFEAATEMIRVSDNTATNLLIRRLGGK +ASLNSRFRSLGLPATVVNNWLPDLDGT------NTTSSRDLARAIALVDTGDKLTPRARD +LFRQIMATSRT-NTLIPLGLPEGITVYNKTGDIGI-AYADAALIELPNGQRAVAAFMVKG +PFND-PRSAELIRAMAGTVA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Ruminococcaceae bacterium D5 TaxID=1520815 RepID=A0A1I3MWM7_9FIRM +------AIRDYTEPFAEKIGLVVHDVRTGAVF-SRNPDRVFPSASVIKLAILWEFYRRVA +EGSLNPEEPYVLHDDVKEGDTGILRDFHDGLLTLQDIVTMMIVISDDTATNILIDRF-GK +EAINESMSRIGLTHTRVQRRMMEYDKV-RAGIDNEISAGDMDRYFTLLLAQDSMPAGCRE +TMLDILARQRY-TAAIPSLLSEDTRIAHKTGTIGFGLEHDVGLIYGPDGRPAVIVAALTQ +HL---ENRLHVIGTIAKMALE-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. SSI9 TaxID=2605433 RepID=A0A5D4GYB7_9SPHI +--KLERILQNEIKDFQGDIGIFVQHLRQNKTV-DIQADSIFPTASIVKIPILAGVFNKIN +LGELKLNSPYLYDAKRVYGGSGLMQFYKDSTTDLSTMVSLMLTYSDNVASIWCQELAGGG +TSINRMMDDLGLPHTKVNSRTEGREEIWKKYGWGQTTPREIAQLMTLIQQGKVITPRLSD +KMYRYLKNQFY-NERSLSQFPAYIATASKTGSVNE-ARGEVVFVHAPSGD-FVFAVLTKN +NTTRDNEAEILTRRIANILWNYf +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. ALD TaxID=2293318 RepID=A0A371TKN3_9BACI +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Bradyrhizobiaceae bacterium TaxID=2072420 RepID=A0A431RGS3_9BRAD +------------------------------------------------------------ +------------------------------------------------------------ +-----FWRSLGDSTSRLDHNEPELNRSPPGNPQDTTAPAAMAGNLRRLVLGEALTPASRT +LLTEWMVNCKTGANRLRGGLPASWTVGDKTGNNGKDASGDIAVVWPKPDTPILITAYVQG +GTPNAAQIEAVFARIGRMVTE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus sp. SMB37 TaxID=2512213 RepID=A0A4V2RKN6_9NOCA +----TDRIRAVFADAGCSGWLHARRCSDDEATlSVHGEERVVLASVYKLPLFLAFCAEVD +AGRIDPRSELRIEPSECTPGSGIATMRDPVTMSRRDIAASMMIVSDNAAADVLLGEI-GT +VAVHDMLARLGLEHTNIVGGTADMYRAYDPAFTSATTAEEMTRLLATVWAGDVLSAEQTG +FVRHVMRSQIW-PHRIAAAFPRGVSVAGKTGTIGI-IRNEVAVVEFPGEHPVAVAVFTRA +ARPSLPLVDAAIGEAARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Pedobacter sp. HMWF019 TaxID=2056856 RepID=A0A2R7KEP2_9SPHI +-pKLEQRLQQLVKGFNGDVGIYVKNLKTGRSA-GISADSIFPTASMVKLAITAGVFNQID +KGQLDYKSVLTYKDSLLYAGEDILGSFKNGEIALSKVLMLMITTSDNTASLWAQSLAGTG +TAINDLMAQYGLTYTRVNSRTPGRQENQKKYGWGQTTPKEMATLLTLIRNGKLINEAASE +RIYRNLIRIYF-DQEALSQIPPYIQAASKSGAVDE-ARSEVVLVNAPHGD-YVFCITTKN +QKTPSNEGWVLIRKLSRMLWHYy +>[subseq from] serine hydrolase n=1 Tax=Mucilaginibacter sp. R11 TaxID=2695265 RepID=UPI001413126E +-kKLTKQLEEAVKGFNGDIGIYVHNLKTGKTA-AFNADSIFPTASMVKTAIQCGVMDKIE +KGELQYNQKLVYRDSLLYAGEDILGSFKNGDIQLSKVAMLMITMSDNTASLWLQKLV-GG +DYINNWLQQNGFNVFRVNSRVPGREAFRKKYGWGMSSPYEMCKLFTMINDGQAVSPAASE +RMMRNLTRIYW-DERALSAIPPYIHTASKQGAVNE-AKSETVLVNAPHGD-YVFSVMTNN +IKTTDNEAEMLITKISTVLWHYy +>[subseq from] Membrane alanyl aminopeptidase n=1 Tax=Haliscomenobacter hydrossis (strain ATCC 27775 / DSM 1100 / LMG 10767 / O) TaxID=760192 RepID=F4KQF2_HALH1 +--ELEAAIKAELARVEGTFYVAFRDLQNPVQAvFINEKISIHPASTMKTPVLVEVFKQAN +QGKFKLSDSIVLKNESIVDGSPYSYQRMGQKVSIYDLARAMIVRSSNLATNMLIELV-GA +ENTTQTMRDLGLQDIMVRRGVEDSK-AYAAGLNNSATAYDLMLLMERIGRGEAGRPVDCQ +EMIKILSDQEF-NDVIPTCLPADVQIAHKTGWITQ-HHHDSALIISPEGRYFSFTILSKG +WT-NETAANEAMGKVVEMAYRYf +>[subseq from] Serine hydrolase n=1 Tax=Emergencia timonensis TaxID=1776384 RepID=A0A415DUX8_9FIRM +-----------LKNCTGKVGFYYKNLITKEEL-AYQENESFIAASIIKLPIFAQVIKVSS +EHRLDLGKEVQIRKEDILPSCGAINLFSSEPLDLRTICNFMIALSDNTATNIMIREC-GI +AALNAGFQEMGLMKTRLERPLFDET-ASMAGKDNYFTPAEIAMLLESLYEERFVSSAVSK +DILQTLKMQNI-NYKIPGLMAERFEVAHKTGEDD-GITHDAGIVYCD--QPFIIVFASNG +TD--------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 3211.1 TaxID=1938843 RepID=A0A397R2Q0_9ACTN +----LRRIAAAFAEAGVSGRLHAVDIDSGTEI-DAGADHPVVTASVHKLCLLVALHQHAA +AGRLDLTEQVECPPDDRTAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL +DGVNEATARLGLTRTRAVHTFRSLFAALDPARGNRSTPRDMTRLLAAVWRDEACTPEHGA +AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA +ANATLPAADAVIGTTARIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Lacrimispora sphenoides TaxID=29370 RepID=A0A1I0I6C9_9FIRM +-------IIKKLERIPGKISFLYEDLKTGEGF-AYHEQEPMMAASVIKLFVMAAAFEKSK +KGTFQMDKLFPVKREDCVPCGALTYLHDGILVTGLDLVTLMIIFSDNTATNILIDIL-GI +EEINDTIQGLGFRHTLLQRKMYDIKRS-SRGIQNYITAYETGRLLKMMYEGTLIDRRSSE +AMISILKNQQL-CSKIPFYLQESPEIAHKTGEDT-GITHDVGIIYGK--EPFL-VCFCGN +ET-DTPAFERVMAEVSLELYK-- +>[subseq from] serine hydrolase n=1 Tax=Arenibacter certesii TaxID=228955 RepID=UPI0003F56093 +-kSLEKGLRELVSDFKGDVGVYVYNLTTNTVA-AINADTIFPTASIVKVPILIGVFDKIH +KGALSLNDTLVYDDKRAYGGAGLMQFYKDSTTDLRTLISLMITMSDNTTSLWCQELAGGG +ETINALMANLGLKHTRVNSRTEGRTKDWDKYGWGQTTPKEMAFLLTKIRNRKMINAASSD +EMYRVMSNSFYTDYSL-SQIPPYIQTAAKQGMVNT-SRSELVMVNAPTGD-YVFYIGTKN +NKDADNEAWQLQRKISAYLWNYf +>[subseq from] class A beta-lactamase n=1 Tax=Kineococcus sp. T13 TaxID=2696565 RepID=UPI001411FED9 +----------------TRAAVWAVDLRSGRRL-DHDGHHQRPLLTLSAGLAAAQLLRTAT +----PLTRRVRYGADDVVPGSPVAGSHVREGMSVAQLCTAALGRGDDTAANLLLQLSGGP +LGLTRFCRSLGDGTTRVDRWAPESASGEPWDPRDSTTARALARDYGVVLLGPALPAASRL +QLRSWLP---T------ALLAGGWSFSHVTATGWYGTAGAVGIARRGTR-QVVIASLVRG +ADASAPGT--------------- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BED8A99 +------------------NGLVRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKEIDNYTCASDVVKCLREIYEGNLLQKSSRG +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNAQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. alain-838 TaxID=2026340 RepID=A0A269TPC7_9ACTN +----AGRLHAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKVCVLVTLHELAA +AGEIDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAALLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFAEMLGALDPARTNRSTPRDMTRLLSALWRDEACPSEYGA +AMRRVMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT +ANATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=bacterium JKG1 TaxID=1128421 RepID=UPI00047862D9 +------ALERWLAAQPGEYSVCVVR--DGAQVyGYREHVPRSAASLIKVPLALAVLDA-- +--GLDLEQRVLLREADRVAGCGSLDAAPAGTATLRQLIVHALVESDNTAANLLIARL-GM +PAVNRWLAEHGLTQTRLRRRFMDLDA-LRAGCDNTTSAAEMCAILALLL------DPRRC +WLLELLRQVAD-DDKLGAGLPPGTPLAHKVGDLP-GVEHDAGIVWTPGG-PLIMAALACA +LP-DAATGRAAIRHIARVVWR-- +>[subseq from] Serine hydrolase n=1 Tax=Caulobacter sp. 774 TaxID=2172652 RepID=A0A2T9K2J4_9CAUL +---MSLKLTAIAERAPSDLGVAVQDLTTAQRA-TVAGEHLFPLAGMWTAALGAAVLAEVE +AKALSLRETLTVEDVDLSPPSEVADAWPGRRWTVEELLKRAVAGGDNTAADVLMKRIGGP +GAVTAWLDLKKVENLRIDRYARQLLPDYLVDPRDSTTPLAAVRFLEALNQGELTDQDGRR +RMLRMMEAAA--GDRLRPALPAGARLAAITSATPTAADNVLAMVRLKDGRRFALAIFLKA +SPMEEADRDAVMLDVMRTILQ-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL F-2747 TaxID=1463843 RepID=UPI0004C850E1 +------------AEAGVSGRLHAVDIDTGTEI-DAGADHPVVTASVHKLCLLVALHQQAA +AGLLDLTEQVECPPDDRTAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL +DGVNEATARLGLTRTRAVHTFRSLFAALDPARSNRSTPRDMTRLLAAVWRDEACTPEHGA +AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA +ANATLPAADAVIGTTARIAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium SCN 70-22 TaxID=1660163 RepID=A0A1E4B5V9_9BACT +--ALRRALDALADAHHGVVGYAVRDIDAGATI-SRRGDETFPTASLIKVPILVTVYDLVA +RGMLSLDDRLTVLGIDKVPGSGTLQFHDGIEVTVRDAAWLMTTISDNTATNILLDRI-II +RRVWDKMEALGLEHTKVHSKTFLRSSSVAMDSSGVTTPNEMARLFELLARGEAVSPSADS +AMLDVLAHNED--NVLLQRYADGVRAAHKTGATD-AVRTECSLFYLTRR--VVACVLTRE +NADQDAEPQLTMARMGEAIVRAw +>[subseq from] serine hydrolase n=1 Tax=Lentzea aerocolonigenes TaxID=68170 RepID=UPI0004C43C63 +-----------------------VGVENGPEV-CHQADDQVVLASVFKIPVAVAYAAEVA +AGRLDETERTRVTSRYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDVVFHRV-GQ +AAVDEVLANLGLHRTRIMGCCEDLFAIVDPARTTSSTPREITTLLDAIWTDRAAAPEACE +QVRRIMAQQIW-PHRLGSGFPSDVQIAAKTGTLPS-VRNEAGVVTYPDGRSYAVAVFTRA +QAPRQPAVDAVIGRAGRLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Clostridiaceae bacterium TaxID=1898204 RepID=A0A3D2P0H7_9CLOT +------KIDELINRLDGEASVLVKNLSTNEVY-KYDENKIFPSASMIKVPILLELIDRSC +ERKINLDDVVEFKKEDIVQGYGIIKSSPGINMTYRDCALLMIILSDNIATNKLIETL-GM +DSINEKIREIGMENTILQRKMMDAEA-KKKGLDNFISGADLLTIFEYLYS-----HEKYN +IAVDILKKQLC-NDLLPVLIGGNIEFAHKTGDLP-GVRHDSGIMYLK--SPIFIAVLTNN +LKND-CDGITFSNEIGKIVYDHy +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0013F464E5 +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIETFRQID +AGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=A0A0M0WJF0_9BACI +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGILRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. Alain-F2R5 TaxID=2026341 RepID=A0A270QWX7_9ACTN +----AGRLHAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKVCVLVTLHELAA +AGEIDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAALLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFAEMLGALDPARTNRSTPRDMTRLLSALWRDEACPSEYGA +AMRRVMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT +ANATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Microtetraspora fusca TaxID=1997 RepID=UPI00082A549E +-------LKEVFDDADVEGFVHVRDVDGSAEI-GLNPDEPVVLASVFKIPVVLEYARQAA +AGTLERTERLTVTAADKDGGIGTSGCADDISLTLRDLAHFMMTMSDNAATDVLLRRV-GL +ENLHATLRGLGLGRTRLVGGCAELLGVLDPERTTSGTPRETTTLLSKIWRDEAGPAEACA +EVRKIMGNQIW-PHRLSSGFGDEVKVSGKTGTLP-GVRNEAGVVEYPDGRRYAAAVFLRT +DSLRLPQADAAIGRAARMAID-- +>[subseq from] serine hydrolase n=1 Tax=Salegentibacter sp. Hel_I_6 TaxID=1250278 RepID=UPI00056248C1 +--ELQQKLEQLTQTFNGDVGVYVKNLKTGKEA-AINADTIFPTASIVKVPILLKIFDKID +KGELKYNDTLVYSEDRIYGGSGLMQFYKDSATDVRTLVALMISYSDNVTSLWNQELAGGG +EAINELLAELDLEHTRVNSRTEGREKDWEKYGWGQTTPREMAIILEKIRKRELISAAASD +EMYRLLGNSFY-QEYALSQIPPYVQAAAKQGMVNK-SRSELFMVNAASGD-YVCYIATKN +IEDDNNEAWELQRKISALLWSYf +>[subseq from] Putative beta-lactamase n=1 Tax=Symbiobacterium thermophilum (strain T / IAM 14863) TaxID=292459 RepID=Q67LM9_SYMTH +---VVRRIERLTRWAPGVVSVWYYDLSTHETF-GVRADEVYTAASTVKVLIANYLYHLAA +TGQVSLDEPLAIRAVDWKDGSGILNGVPDGTLPLREVARLMLVHSDNTAANALMRRL-GV +QPMVQYYRSLGIR-----YGTPRMHTPGELWEGNRIAPEDLGIVLRNIWEAARRSPEPWE +ELLGFMRESRS-KGRIPAGLPSHVPMANKTGSKGT-SFHDAALVL--DRRPYVLVVMTQG +MT--ARQASHYIAAVSREVWE-- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. BO 8801 TaxID=169670 RepID=UPI000B9888D3 +----SQQWARLAAAQGLTASAFLLVLDDGRFA-QLQPDLPLSAASSIKVPILLASLEDLD +GGKLRWNEPMPLTKEVVGGGAGWMANPLGTRFPFFEAATEMIRVSDNTATNLLIRRLGGK +TNLNTRFRSLGLTATVVNNWLPDLDGT------NTTSSRDLARSIALVDTGDKLTPRARD +LFREIMATSRT-NTLIPELLPEGITVYNKTGDIGI-AYSDAALIQLPNGQRAVLALMVKG +PFND-PRSAELIRAMAGAVTK-- +>[subseq from] serine hydrolase n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=UPI0012FF2731 +-eELTAQTVRIIGDTKNQMAVYFLRPDREIEP-FVYNSQQMAPASMIKLFVMAKTMQDVH +DGKLSLEEKITIKKSDAVGGAGVTTWYDAGERTIQQLMTVMITDSDNTATNILIDRL-GM +QNINQYLQQQGFNDTVLVYKMMMGR---KGKKKNLSSARDIGKLLSRLYYHQLVGEQEDE +LMRDILCQQHD-KECFPAALP-DYEIAHKTGEVND-VYVDGGIFFGQKED-FVLVVLSNG +KAGR------------------- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus geothermalis TaxID=68909 RepID=UPI0002F17F48 +-------------GYVGEVGVLITDLAGRELY-ALNPDRVFPAASTIKVPLLLLALSEAQ +AGRLDLSGRVTLRAEDRVPGAGVLHELMPGLPTWQDLLTLMIVVSDNTATNLVIERL-GL +DRVNDWLGERGLSGTQLVGPLERQNAAQRRGERNRTTARDQVALLGALVRGELLDRSHTG +LALSILERQQL-REILGRHVPCDYRVASKSGELM-GIHHDVGVLFTP--RPLIAAVLSQG +GL--------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004BD7A56 +--SVAARLDAAFADAGVTGWLHAVDVDSGAQV-GTRAEQPVCTASVHKLCLLVTLHELAA +AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. MW101C3 TaxID=210768 RepID=UPI000B9825E4 +---LSARWKALAAQKDLKVGGFLLVLDDGRFA-QLNPDTPLPAASSIKTPILLAALEDLD +RGKLRWGEPLPLTKEVVGGGAGWMANRPGTRFPFYEAATEMIRVSDNSATNLLIKRVGGK +LAINARFQALGLPATVVNNWLPDLEGT------NTTSPHDLARSIALVDTGAKLSPRARD +HFRTILGTSRT-NTLLPAGVLKGITVLNKTGDIGI-AYSDAGLIELPNGQRAVAAFMVKG +PFND-PRSTDLIRAMAAAM---- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus maanshanensis TaxID=183556 RepID=A0A1H7TP82_9NOCA +------------------------RVDDGDAV-SVEADDLVVTASVYKLPLLVALCREFD +TGALSPTATVRVNPADCTPPTGVSIFRDPVVMSWRDLALSMMTVSDNAAADLILGSV-GL +DGIDRVLTELGLSRTRIIGGTADVHRAYDPAFASATTPREMTSLLDAIWTGRAVSAAQTE +FIREVMAGQIW-PHRIRSGFPAGVTVAGKTGTIG-AIRNEVAVVGFPGETPVAVAVFTRA +ARADLPVVDQAIGRAAHIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Cytophagaceae bacterium SJW1-29 TaxID=2654236 RepID=UPI00128D0EFA +-kALTRQVAEAVKGFNGEVGVYIRNLRTNRTV-EINADTLFPTASMIKVPILCGVFDKLE +KGELRYDQVLTYRDSLHYDDGVVGSLRDSAQIPLSYVLMLMETLSDNTGSLWMQALAGGG +TSINQWMEKQGFQKTRVNSRTPGRQEAQKTYGWGQTTPREMAELVVMIRAGKAVSPAASE +RMYRLLGRQFW-DGYALSQIPPTIQVIAKNGAVDQ-AKSEVVLVHAPHGE-YVFCITTKN +QTQPDNEGYMLLRKVSRLIWNHy +>[subseq from] serine hydrolase n=1 Tax=Arenibacter latericius TaxID=86104 RepID=UPI0004145123 +---LESGLKDIVSDFKGDVGVYVYNLKTNSEA-AINADTIFPTASIVKVPILTGVFDKIN +KGELSLNDTLIYDTKRAYGGAGLMQFYKDSTTDLRTLISLMITMSDNTTSLWCQELAGGG +ETINALMANLGLKHTRVNSRTEGRTKDWEKYGWGQTTPREMASLLTKIRNRQLVNAASSD +EMYRVMSNSFYTDYSL-SQIPPYIQTAAKQGMVNQ-SRSELVLVNAPTGD-YVFYIGTKN +NEDVDNEAWQLQRKISSYLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces tendae TaxID=1932 RepID=A0A5P1YD78_STRTE +----VARIHAALADAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHERAA +RGELDLTEQVETVPGDRTAPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLSRV-GL +DAVNTATARLGLTRTLAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEAGLPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus erythropolis TaxID=1833 RepID=UPI00061B83FF +--SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE +EVRTIMSKQVW-PHRLSSDFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia concava TaxID=257281 RepID=UPI000592E100 +-----------FRTAGVEGRVHARCFDCDGEF-GWNADEPVVLSSVVKVPLVLEFARQVA +AGQLDATDRVRATAADRLGGVGTAGCLDDVEYSLRDAACLALTISDNTAADLLFDRV-GV +ENVRSLVRELGLTRTRVEGSIRDILYAVDPLRTTAGTARDMTRLLRLIGRDEAGAPEACA +WVRDLMRQQAF-GHRLPSGFPPGVDIWSKTGTLP-GIRNDIGVVGYPDGSRYAIAVFTVS +HSGRQPAVDRAIGEAARLAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus faecimaris TaxID=686796 RepID=A0A1G6N8J1_9BACT +--SLQQKLDLLSADFKGELGVYVEHLSNGESA-QLNADSIFPTASIVKIPILLGIFDKIE +KEELHYHQSLIYRDSIKYGGSGLMQFFQDSTTDLRTLIALMLSYSDNTASLWLQTLAGGG +ETINPLLEKWGYLHTRVNSRTQGRAKNWENYGWGQTSPREMANLLRKIHEGSLFGPAYSE +QMSRLLSNSFY-TEYALSQIPPTVNVLSKQGMVN-ASRSEVLLANAPKGD-YVLAIFTKN +NEDETNEAWSLSRKISNMVWDHf +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. 1001175st1 A10 TaxID=2559709 RepID=UPI0011063B05 +---IEKRIEAELMSYDGTMGIYADDLH-GNII-AIGADEPFETASTIKTYILACLFDQVE +KGKASLEDMVEFKEEHTVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL +DTINACIRGLGCRDTVLYNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPESDA +KMLEIFKKQHY-NSMITKDFPAVVTVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNRK +FSDAAHPATVFGARVSRLLFDQf +>[subseq from] Serine hydrolase n=1 Tax=Chryseolinea soli TaxID=2321403 RepID=A0A385SPX9_9BACT +---LTGKLQETLQGFKGVAGVYVRNLRTGKTV-TINADTLFPTASMIKIPITIGMFDRID +RGEIDYHTLLTYKDSLLYEGEDILGSFKNGEIALSKVMMLMITTSDNTASLWCQSLAGTG +TAINAWLEKNGFENTRVNSRTPGREANRTRYGWGQTTPREMAELVTRIRDGKVISPRASE +RIYRNMIRIYW-DSESLSQIPPYIQAASKQGAVDQ-SRSEVVLVNAPHGD-YVFCVITKN +QETPANEGYVLLRKVSRLLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Pedobacter sp. TaxID=1411316 RepID=A0A519WTJ9_9SPHI +--KLNAMVADLAKDFKGDVGIYVKSLKTGKVA-SFNADTIFPTASMIKVPITCGIFDKIE +KGELEYKTQLIYKDSLLYAGEDILGSFKHGEIWLAKVLMLMITTSDNTASLWSQSLAGTG +VAINQLMEKYGFEHTRVNSRTPDRQANQRKYGWGQTTPREMATLLTLIREGKMISPAASE +RIYRNLIRIYY-DNDALSEIPPYVQVASKSGAVN-ASRSEVVLVNAPHGD-YVFCIITKN +QQKHDNEGYALIRNLSKMLWNYf +>[subseq from] Uncharacterized protein n=1 Tax=Clostridium sp. SCN 57-10 TaxID=1660094 RepID=A0A1E4LQT6_9CLOT +----KDQISALLAPFGEHGSFVWKDLVTGEGM-EWGAHTPHNAASIIKIPVMVELFRRFE +DGSACKDTLLPLRDCDRVPPCGVLTFHEGMPVSLMDLCWLMITISDNMATNMLINYL-TV +PAIQETMRALGLQNSMLERKLFETDPA-LRNKRNRISAADMALLLEQMHRGELISERASR +EMLDVLSGQQL-NNKIPFLLPLDMHIAHKTGEVDD-VTHDVGIIYAKRPQ---LVCFCSS +D-VDAPAFNQVIFTISKLIFD-- +>[subseq from] ClassA (Fragment) n=3 Tax=Bacteria TaxID=2 RepID=A0A127SGH1_9BACT +------------------------------------------------------------ +-----------------------------GDFSLKELLRVTVQESDNNTCDLLFALIGGT +ETVQKDLKEWGISGINVRFTEDEMLRNHELQYANSSRPSAMNALLRAFDEGKILNKDTQR +LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD +SKDSAPACEKVIASMARWLCTEw +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. ASBs410 TaxID=1304866 RepID=UPI000452A28E +-------IIKKLERIPGKISFLYEDLKTGEGF-AYHEQEPMMAASVIKLFVMAAAFEKSK +KGTFQMDKLFPVKREDCVPCGALTYLHDGILVTGLDLVTLMIIFSDNTATNILIDIL-GI +EEINDTIQGLGFRHTLLQRKMYDIERS-NRGIQNYITAYETGRLLKMMYEGTLIDRRSSE +AMISILKNQQL-CSKIPFYLQESPDIAHKTGEDT-GITHDVGIVYGK--EPFL-VCFCGN +ET-DTPAFERVMAEVSLELYK-- +>[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. E2A TaxID=2665642 RepID=A0A5Q3Q5U8_9PSEU +----------LPGDCPGRLGFAAWHLDENEPV-LIGQTRQVDAASTIKVLVMITALRAVQ +DGTMRWDSCLPLPEGDRVGGTGVLRELHGLRMELTDLITLMIVISDNVATNTVIDAV-GC +DAVTDTAVSLGCPDTQLQRHLNDMRAQ-AAGLDNVTTAVDQARILAALASGHALDPGTTR +HALGVLARQQV-RDRLPARLPWDARCWNKTGEESC-LRHDVGLIGTGDRPEAVVAVLIDD +LTDS------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces luteus TaxID=1915400 RepID=A0A086N0N2_9ACTN +----TGRLHSAFADAGVTGWLHAVDIDSGAQV-EAGADQPVCTASVHKVCVLVTLHELAA +AGEIDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAALLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRTVYGFAEMLGALDPARTNRSTPRDMTRLLSALWRDEACPSEYGA +AMRRVMSLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +ANATLPAADAVIGTAARIAVD-- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus insicii TaxID=1732567 RepID=UPI000F7A553F +-------------GINGETSAYYFGINDNKKA-SYNYDAEQRAASDIKLFIMAAAYREVS +QGNISLSDRYTLTDADKVSGTGVVQSMQSGDLTYEDLINYMITKSDNTAANIITKQIGGI +SVVNEEINRLNLNDTRMERMLMDQD-ALDSGKDNMSSAYDLALFLKKLYEHKVVSTKYDN +EMLSILSNDSN-HSKLPNQVNTDVIIYNKTGEFGYGVENDAAIFKHDNKA-FVLVVMSQD +GSSS--EQKSAMSSLGKDV---- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. RTd22 TaxID=1841249 RepID=UPI00099FE305 +---ARRTIRGLFADAGVRGWLHVADLRRPEACvAIDPDEPVPVGSVYKVPLMVAFWRLVD +AGTLDPCERMTLGPSDRIPPTGISILRDDITVSLRDLVALMMSVSDNTAADVLLRRV-GT +PAVDEVCRDLGMPDTRIHGGVATTFAVYGPVLKSSATPADMARLLRAIWTGRAASADACA +FMREAMGRQPW-THRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELADGSAYTAVVFTQA +ARADLPRADAVIGAAARTAVE-- +>[subseq from] serine hydrolase n=1 Tax=Emergencia timonensis TaxID=1776384 RepID=UPI00083455B7 +-----------LKNCTGKVGFYYKNLITKEKL-AYQENESFIAASIIKLPIFAQVIKVSS +EHRLDLGKEVQIRKEDILPSCGAINLFSSEPLDLRTICNFMIALSDNTATNIMIREC-GI +AALNAGFQEMGLMKTRLERPLFDET-ASMAGKDNYFTPAEIAMLLESLYEERFVSSAVSK +DILQTLKMQNI-NYKIPGLMAERFEVAHKTGEDD-GITHDAGIVYCD--QPFIIVFASNG +TD--------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNH189 TaxID=1136432 RepID=UPI0004651B46 +----VARIHAALADAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHERAA +RGELDLTEQVETVPGERTAPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL +DTVNATTARLGLTRTLAVHSFGEMLAALDPARANRSTPRDMTRLLGAVWRDEAGLPEHGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus niacini TaxID=86668 RepID=UPI0005EE5964 +---LKEKIREELNEFEGRIGLAIEI-EDAGNF-YIDNEKVFRSASLIKIPILLAGLGRHK +IGELDLEQLIHISKENRAGGSGILYALSDQLLTVKDLMTLMIIVSDNTATNILIDLL-GM +DEINAFIKEIGFEHTKLNRKMMDFA-AIEKGMDNFTNPREMIHFLKLLNENDIIGITGPP +IAYHALRHQQF-RDKLPAMVNEKITVVNKTGELPS-VEHDCAIFEYQGRK-GYVAVLTDS +FI-DQNAVKQIIRNIGKHISDFf +>[subseq from] D-alanyl-D-alanine carboxypeptidase family protein n=1 Tax=Bacillus megaterium (strain ATCC 14581 / DSM 32 / JCM 2506 / NBRC 15308 / NCIMB 9376 / NCTC 10342 / VKM B-512) TaxID=1348623 RepID=A0A0B6ADU9_BACMB +------------------NGLIRIHIEGKESI-RINSFIQQRAASTIKLLLAIEAFRQID +AGILALTSVIQRMEKNTVGGAGVLKALPQLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGSLLRKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Eggerthellaceae bacterium zg-887 TaxID=2682777 RepID=UPI001407E194 +--NLAATVSGIISSYGANASVTLSDLDDYATF-AVDGSEPHVSASMIKLAIMAEVFDQVN +SGYLALEDSYTVQESDIVGGTGTLQGGPGTQLSLSDLVRHMIAESDNVATNMLIDLV-GM +DAVNEEVAKLGLNATSLQRYMMDTDAQ-AAGIENHMSSDDAAVILILIANGEFYTPELSQ +LATDFLSQQTD-AGGIAPSLSSGETFAHKTGTLTN-VRHDAGIVQ--GEAPYVLSVFVEG +TDEG--SALSLMGEVT------- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus tucceti DSM 20183 TaxID=1423811 RepID=A0A0R1J947_9LACO +----------NLSGIKGDTTAYYYNLDDDTTA-SYDAKTPQRAASDIKLYIMAAAFQKIA +DGDISLNDRYELTNDDKVGGTGVTQNMQAGELTYRDLIDYMITKSDNTAANIITKEVGGM +SAVNDEIEKLGLDNTKMERMLMDQD-ALAEGKDNKTTSYDLAIFMKKLYRHDVVSAKYDK +EMMSVLSNTSN-HSKIPAEINTNVDVYNKTGEYDYGVENDAAILKRDNKA-FVLVVMSQN +GDSD--EQKDAMGSLGK------ +>[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. RB68 TaxID=2585200 RepID=UPI001294C997 +-------IEEVFRAAGVTGHLHAADIDTGREL-GVGSDEPVVLASVFKVALLVAFFREAA +AGGLDPAEQVVLRAADRAPGPTGTAILLDDVMSLRDLAALMITVSDNAAADVLYQRV-GR +GTVNATLRLLGLTRTHLAGGIRDMQDALDPARTTRGTPRETAALLAMIWRDEAAPPAECA +QMRRMLGLQVW-PHRLSSGFPDDIVVSGKTGTMAT-IRNEAGVVEYPDGGRYAVAVFTRS +LLAVLPQADAAIGTAARLAIE-- +>[subseq from] Serine hydrolase n=1 Tax=Planomicrobium sp. MB-3u-38 TaxID=2058318 RepID=A0A2I0FJ93_9BACL +-rKLEAQVENALERFLGQASVVIET--GDDRI-DFNGHAQMKSASTIKLAVLLEAYRQVD +QNLMKTYDLISLKPEDFTEGSGVLFYLDSVKLSFEDLLTLMIIVSDNTASNIAIQIV-GI +DNINQLLQRLGCAETVLERKFMDFHSALEG-LDNYTSAADLVILLKAVDSGGLLSEDSRR +RVLHILKKQQL-LAGLHGRIEDEVTVASKSGSLP-GVVNDAGIFEYRSNK-VYTAVLTAD +SP-DHHSGQELIAEIGGYIYD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus jeotgali TaxID=129985 RepID=UPI0009A566FC +-nELKDQLAKELASCKGRASLFLEI--EGRII-EFTGNEVYQSASLIKLPVLFEALRQID +KGILELDRPVAVRQGDRIGSTGVLQAMNIKQITIHDLLALMIIVSDNSAANMVIDLI-GM +DTINSNLSKIGMHNTVFKRKMLDFK-AIQTGDDNLTTCADIVLCLKEAMEGQWLAKQSSQ +LFHAFLLQQQI-QEKLPAQMNSLYKIGNKTGELA-GIEHDCAVITYGTKR-AYAAILIDQ +LD-DNESGKSIIRQIGKRI---- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus apachensis TaxID=309886 RepID=UPI0003A29D99 +------------HGYAGEVGVLITDLAGRELY-ALNPERIFPAASTIKVPLLVRALHEAQ +SGRLDLRERVTVREEDRAGGSGILHEFGPGLPTWEDLLTLMIVVSDNTATNLVIDRL-GV +ECVNGWLDGLGLGSTRLVGKLERQNEAQRRGERNRTAAWDQVNVLGKLARGDLLDPVHTA +LALSILSRQQL-RDILGRHVPRGYRVASKSGELL-GVHHDVGVLFTP--RPLVVALLSEG +GL--------------------- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Atopobacter phocae TaxID=136492 RepID=UPI00046FA53F +-----------------------------ASI-SANGNVPIRAASVIKIFILIAFYQQVD +EGAINLEDTYQLRTADKVGGTGNIQNPPGTTYTYNQLATEMITNSDNTTANIVIDRIGGL +NAVNQVIAKLGYTQTKLNRKFLDTY-ALSAGIDNYVTSEELGDVLTKLYQRKLINEKVDQ +SVLDILGKQID-REKLLKNLPTNLVIYNKTGQFDYGVMNDAAIIVTDKG-SYVLVALSMD +GRY--GEKAPAIARFSQNVYQQf +>[subseq from] serine hydrolase n=1 Tax=Rhodothermaceae bacterium TaxID=2026787 RepID=UPI000DD35757 +--ALQARLEHLVEGFRGDVGIYVRHLPTGREA-AIQPDTLFPTASLIKVPILLKTFDAIE +QGVLDYHQPLVYRDSLYYPGEDLIGALKDSSIALSKVVMLMITTSDNTGSLWLQGLVGGG +TAINDWLAAHGFEHTRVNSRTPGREAAREVYGWGQTTPREMAEMLVMIREGRAVSPAASE +EMYRVLTRIYW-NDEALSQLPPTVQTASKQGAVSR-SRSEVVLVNAPHGD-YVFAVITKN +QETHDNEGYVLLRDVSRLLWQYf +>[subseq from] serine hydrolase n=1 Tax=Pedobacter sp. P-25 TaxID=2563444 RepID=UPI00110C89A1 +--KLNKMVNELVKGFNGDVGIYVKSLKTGKIA-AFNADTIFPTASMIKVPITCGIFDKIE +KGELDYKAQLTYKDSLLYAGEDILGSFKNGEIWLAKVLMLMITTSDNTASLWCQSLAGTG +VAINNLMEQYGLQHTRVNSRTPNRQANQRKYGWGQTTPREMATLLTLIRDGKMISPAASE +RIYRNLIRIYF-DKEALSEIPPYVQVASKSGAVNE-SRSEVVLVNAPHGD-YVFCITTKN +QKDTDNEGEVLVRKLSKMLWNYf +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. RP1137 TaxID=1380110 RepID=UPI0003FFBAA5 +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVILIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. CNU-125 TaxID=1904961 RepID=UPI0011789F03 +-----------FRNAGVTGCCHAVDIDAGRDV-GVRADEPVVLASVFKVPLLVAFHRRVA +AGTLDPTERATLPAADRTSPTGVSALLDDVRMSLRDLATLMITVSDNAAADFLLDRV-GL +AAVNAAAADLGLPATFVAGSGREMLDVRPLDPTSRSTPREMTRLLSLVWRDEAAGPGECA +AMRRMFGLQVW-PHRLSSGFPEDVVVSGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRT +PVAVHPQGDAVIGTAARIAVEH- +>[subseq from] serine hydrolase n=1 Tax=Planomicrobium sp. Y50 TaxID=2213011 RepID=UPI001091DCF7 +----EFQVKKALEHSSGKVSLAIET--KNGRI-DINSHKQMKSASTIKLAVLLEAFSQID +RDLVKPYDIIRLQPEDFTQGSGVLIHLGSVKLSFEDLLTLMIIVSDNTASNLVIRTV-GI +DSVNALLNRLGCNETVLGRQFMDIQAALD-GLDNFTSAADLVTMLKVVDSGELLSEDSRR +RVLHILKKQQL-LANLHGRIDDEVSVASKSGSLP-GVVNDAGIFEYRGDK-VYAAVLVSD +SP-DNHSGQEVIAEIGGYIYD-- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus sp. 184-8 TaxID=2486005 RepID=UPI000F7A7A4E +-----------LSNIKGDTSAYYYDLNNNSTA-SYDANSAQRAASDIKVYIMAAAFQKIK +DGDISLNDRYELTSDDKVGGTGIVQDQVGDSLTYRDLIDYMITKSDNTAANIITREIGGI +SSVNSEIDKLDLSSTKMERMLMDQ-DALDEGKDNMTSAHDLAVFMKKLYRHDVVSAKYDK +KMLEILSNTSN-HSKIPAKINTNVDVYNKTGEYDYGVENDAAILKHGNKA-FVLVVMSQN +GDS--DEQKDAISSLGKDVTQ-- +>[subseq from] Beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=A0A2X2YN99_CITKO +------------------------------------------------------------ +------------------------------------------------------------ +------MRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQLSSRE +QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ +TPATMAQRDAAIVRIGESLF--- +>[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. J1-007 TaxID=2661913 RepID=UPI00132122C8 +---VTARIEAAFRAAGVTGHLHAADIDTGREI-GVRPDEPVVLASVFKVPLLVAFHRQAA +AGLLDPTEAVTVRPEDRSAPTGISALLDEVRMSLRDLACLMITVSDNAAADVLLDRV-GL +AAVNETAARLGLPRTYVDGGGRDLYDGLDPARTSRSTPREMTRLLGLVWRDEAAPPDGCA +AMRRLFGLQVW-PHRLSSGFPDDVLVSGKTGTLLT-VRNEVGVVEYPDGGRYAVAVFTRS +SLAALPRADAVIGTSARMAVE-- +>[subseq from] serine hydrolase n=1 Tax=Mycolicibacterium madagascariense TaxID=212765 RepID=UPI00138D7E7F +------RIAAVFADAGATLHAVAVDGSSTGEV-NVDGDRPVALASVYKLPLLVAMMRMVD +GGRLDLTERVTLRPTDRTAPSGISALLDDVTMSWRDLAAMMMSVSDNAAADAILQRV-GV +DEVADALSALGLTRSRILGGTADAYRAYDPLQSSSATAREMTTLLRTIWTDVAASPASCA +TIRRLMSLQVR-SNRIASGFAAGVSVAGKTGTMG-ALRHDVGVVRFDGERPYAVAVFTQS +ARATQPRIDAAIGQAARLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Fischerella sp. PCC 9605 TaxID=1173024 RepID=UPI0012DCD1B9 +------NFTSLISGFRGTAGIVIRNLDSGHDA-QFNQELLFPAASLIKLAILWEFFYQCA +IGVVDPVEEIELQAQDMVIGFGVLRQNPGLKLRLLDLATLMIVISDNTATNLLIDRL-GM +DNINNSIQQLGLVNTALQYKMFDPRDV---NRDNFTSPADVARILEAFVRQRQLLGQYGD +EPLRILEGQQC-KNKLHLGLPKGVQLANKTGELLW-IEHDAGILFAKDKE-IVIVVMTQG +LSEN-YDGIRLCRDVAKLVYQ-- +>[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534HVR7_9GAMM +----------------------------------------------MKVAVLIELYRQAR +QGKLKLDDPLSVKNESLVDGSAFAYRAVGGTRTLRELSELMITVSSNLAANLLMDRL-GV +ENIRAGVHALGADGMNVLRDLEDAKA-FEQGLVNTTTAQALLTLLEAIARGQAVDRESSR +QMLETLERQTI-NDGIPAGLPAGTRVAHKTGDITR-IWHDAGIVLA--RRPFVLVVLTRG +LEN-PKESTALIAEITRELYR-- +>[subseq from] Beta-lactamase n=2 Tax=Pediococcus claussenii TaxID=187452 RepID=G8PER7_PEDCP +---------------SGKNSFYIGPTDTKISP-YSQNNAPQRAASDIKIYVMATVFSQMK +QNKFDMNDTYTLKDSDKVGGTGKVQNMGDGTLSMQELMDYMMQDSDNTAANIIIRKLGGL +NVVNDEITHLGFKDTKLERYLMDTD-ALKEGKDNMTSVNDLGTILTDIYNKKLISSSYDE +QMLQILNQDED-HSKLLEEIPGSVSTYNKTGDYDYGVQNDAAILSENGR-SYVVVAMLEN +GSKD--DQTSALNDLGKQVYEKy +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. KPB2 TaxID=2305221 RepID=A0A3Q8VX05_9ACTN +--ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GTGADQAVCTASVHKACVLVTLHELAA +AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEIGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Sphaerisporangium album TaxID=509200 RepID=A0A367FQB4_9ACTN +--------AGVFRAAAVTGTVHAVDLDTGAEV-GVGPDEPVVLASVFKLPLLVEFHRQAE +AGLLDPAEPCRIGPEGRTAGTGLAAMLDAATLSLRDLAYLMIAVSDNAAADVVAARV-GL +KAVNAMLTAFGLTNTWIEHDCRGLLAVLDPANTNRSTPREMTRLLGMVWRDEAAGPPACA +AIRRLLGLQVW-PHRLASGFPDDVVVSGKTGSLPT-IRNEVGVVEYPDGGRYAVAVFTRS +LGQNQPRADAAIGTVARAAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SID10362 TaxID=2706021 RepID=A0A6B2RNR8_9ACTN +---AAARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQAVCTASVHKACVLVTLHELAA +AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEIGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGAAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces diastaticus TaxID=1956 RepID=UPI000C9A2610 +--ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQAVCTASVHKACVLVTLHELAA +AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEIGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=2 Tax=Patescibacteria group TaxID=1783273 RepID=A0A0G1FKA2_9BACT +----LTQIKKIIDQQPGNYSVYVLDLINNQAF-GINESVILTAASVNKIPILATLYKDAA +AGTIDLNEIITLQPNDIQYGTGILQGEGPGGYSLKSLAQLMIKKSDNTAAFVLMQKL-GA +TKVQGTVNNLGLTQTNIEE--------------NLTSNKDMALLFQKIYSGQIVTKTNTR +ALLEMMSNSDF-ENRLPALLPKNVKVYHKIGTEV-GFVHDVGIVETIGH-PYYIGVMTSD +ISG-EEQAETTIGQISLLVYQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Veillonella atypica TaxID=39777 RepID=A0A133S5Z3_9FIRM +------------------------------------QSHRVRAASMIKVYILSYLFEKID +KGEISLQDVYVLKPSDKVGGSGVLNGYESGSLSIDTIARLMITESDNTATNILIDKL-GL +ENINLYISTQGYKDTQLNRKMMDVN-AIDKGIDNYTSAQDLGNWFLKLAAGKMASDLSNK +QMIDYLVGQTD-TECISAALPN-RIIAHKTGELA-GVYHDGGIIYNANHNDYYILVLLSD +GYDSRTGTIESFRSIARQV---- +>[subseq from] serine hydrolase n=1 Tax=Sphingobacteriaceae bacterium DW12 TaxID=1550091 RepID=UPI0005323211 +-dKLTKKLTEAIAEFKGEVGIYVKKMNSNKEV-AIHADEIFPTASIVKVPILVGLFDKIN +NGELKYKQKFIYRKDRIYGGSGLMQFFKDSVTDLATMAALMIGYSDNVTSIWCQELA-EG +TKINNIMDKLGLKNTKVNSRTPGREAAWKEYGWGNTTPREMANLLIMIRKGQVINPSISD +KMYRVLGNVFY-NERSLSQVPAHIKTASKSGSLDD-VRSEVVLVNAPSGD-YVFSIFTKN +NQGQTNEAEDLTRRISNLLWNYf +>[subseq from] serine hydrolase n=1 Tax=Planomicrobium okeanokoites TaxID=244 RepID=UPI0009FEC424 +-rKLEAQVKNALERFLGQASVVIET--GDDRI-DFNGHAQMKSASTIKLAILLEAYRQVD +QNLMKTYDLISLKPEDFTEGSGVLFYLDSVKLSFEDLLTLMIIVSDNTASNIAIQIV-GI +DNINQLLQRLGCAETVLERKFMDVHSALEG-LDNYTSSADLVTLLKAVDSGGLLSEDSRR +RVLHILKKQQL-LAGLHGRIEDEVSIASKSGSLP-GVVNDAGIFEYRSNK-VYTAVLTAD +SP-DHHSGQELIAEIGGYIYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_1_20CM_2_65_9 TaxID=1803428 RepID=A0A1Q8ASG7_9BACT +----ASRAGEIAAGLDGALGVSVFDYLSGFAW-GLDGDRWFHAASTIKVAILAGLFDAIE +RGRFTLDSRLHVRNRFLSGGQPFRHASIGKTMRVGELARHMIVRSSNLAANLLLDLV-GV +EETRAALAARDITGVDVCRGVED-ERAFEAGLSNRVTADGIVGLLRAIRDGRGFSPESSK +AMIDILMDQEF-AGGIAPGLPAVARVAHKTGDIST-VSHDAGLVFLPGRPPYVVAILVAC +AS-DASARTEALAAISGLVYD-- +>[subseq from] serine hydrolase n=1 Tax=Planococcus sp. CAU13 TaxID=1541197 RepID=UPI00052FEDF3 +----KSRILTTLGEFTGRVSAVIE--TAGKRI-DINGNARLKSASTIKLAVLLEAFRQVD +REILKPHELIPLHPEDFTEGSGVLFRMNSVKLSLEDLLTLMIIVSDNTASNVSIRTV-GI +ENVNRMLEELRCSETVLGREFMDFRAA-AEGADNWTSAADLVKMLKAVDLEGFVSPDSRK +RVLHILKNQQL-IANLHGRIDAEVEVYSKSGGLP-GTVNDAGIFEYRGHK-VYAAVLLDD +SP-DNHTGQEIIAEIGGHIY--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces purpureus TaxID=1951 RepID=UPI00036EDCA9 +----RTLLASAFTQAGVEGYVHARDLETGAEF-GHGADTHVVLASVFKIPIALEYARQAA +AGELDPARRHTVTAAYRAGGSGTDGCAYDVEMSARDLAFMMMTISDNAATDLLLDVV-GP +DRVRATLDDLGFKDFGFSSSAA-LDDACAPSTSPSSTPREVTALLAAIWRDEAGPASACA +EVRDIMGQQVW-QHRLVSGFPAGVRIAGKTGTDF-AVRNEAGVIEYPDGKRYAVGVFLRT +STAAQPLADRAIGRAARIAVDH- +>[subseq from] Serine hydrolase n=3 Tax=unclassified Synechococcales (miscellaneous) TaxID=1983103 RepID=A0A3D0PDN6_9CYAN +-qALSRRLAEIAAQKDLKVGAFVLVLDDGTFA-QLHPDRPLSAASSIKTPILLVAFEALD +QAKLSLNEALSLNKTVVGGGAGWMGSQPGSQFSIFEVATEMIRVSDNTATNLLIQRLGGK +DSLNARFIELGLEGTMINNWLPDLEGT------NTTTPRDQARAIALVETGQTLSPRSRD +LFRQTLGTSRT-DTLIPRGWLRGVRVYNKTGDIGI-AYVDSALVELPDGRRVVASYMVEG +PFND-PRSTNMIRALAAA----- +>[subseq from] Beta-lactamase n=1 Tax=Deinococcus phoenicis TaxID=1476583 RepID=A0A016QLP6_9DEIO +------------RGYAGEVGLVITDLTGQELY-ALNPARVFPAASTIKVPLLVLALWEAQ +AGRLDLRERVTVRAEDRVPGAGVLHELGAGLPTWEDLLTLMIIVSDNTATNLVIARL-GT +ERVNGWLRERGLLGTQLVGPLERQNEAQRRGERNRTTARDQAALLGALVRGELLDTAHTG +RALSILSRQQL-RDILGREVPCGYRVASKSGELR-GIHHDVGVLFTP--RPLVVALLSEG +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF2CFE1 +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGILRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVILIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Anaerocolumna sp. CBA3638 TaxID=2696063 RepID=UPI001373A736 +-----ERLLEQLKSLKGDISFYYKNLITGEVI-GFKENIPLEAASVIKIPILIEAFLRIS +EGNIHKDDIIAIKKEDKLPSCGALNYHDGLRVTFEDLYTLMIILSDNTATNLLIKQL-GM +DNINITMQNLGLKQTKLNRLLFDAKQS-ALGIQNYISAGEMGYLLEKMYFGELISPESSL +EMLRILKNQRL-NGKIPFYIHGRADVAHKTGEDD-GITHDVGIVYAPQ--PFVVCF--CG +NKVDVPVFERFMQDITLT----- +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus claussenii TaxID=187452 RepID=UPI0009F443A0 +---------------SGKNSFYIGPTDTKISP-YSQNNAPQRAASDIKIYVMATVFSQMK +QNKFDMNDTYTLKDSDKVGGTGKVQNMGDGTLSMQELMDYMMQDSDNTAANIIIRKLGGL +NVVNDEITHLGFKDTKLERYLMDTD-ALKEGKDNMTSVNDLGTILTDIYNKKLISSSYDE +QMLQILNQDED-HSKLLEEIPGSVSTYNKTGDYDYGVQNDAAILCENGR-SYVVVAMLEN +GSKD--DQTSALNDLGKQVYEKy +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CB02959 TaxID=2020330 RepID=A0A2M9LVX5_9ACTN +--TTRRRIRAAFAGAGVTGRLHALDIDSGAEV-DAGADDAVVTASVHKLCLLVALHQQAA +AGRVDLTEQIECPPDSRTAGPTGLAAMLDPVMSLRDAAYLMMAVSDNTAAGLLLNRV-GL +EAVNSTTAGLGLPRTRAVHTFHEMLAALDPARTNRSTPREMTRLLGAVWRDEACPAEHGA +AIRRLLGLQVW-PHRLASGFPDDVYVAGKTGTLPT-VRNEVGVVEYPDGGRYAIAVFTRA +ASATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Komagataeibacter hansenii TaxID=436 RepID=UPI00094FD6CF +--TLAQDVAKTVSGQPGSFAVYAAMSGQRPQV-CLNCTDYINAASTMKLFVMDAAYDMFT +RGTLQPQETIVVHNRSLVGTRSFSYAQIGRPVTVSELVRVMIQYSSNLATNLMVERI-GV +PYIHAVMHAQHLKGVRFGRMIEDYDAN-DKGIRNEMTAKGLGMFMQKLDQGKIVGPAQSA +AMIDILRGQTF-NDMIPPGLPPGTPVAHKTGWVD-GVRNDAGIVFLPDGRHYILVMLTKS +LP-DEAAGIRVLNGISRQVYGHf +>[subseq from] Beta-lactamase n=2 Tax=Komagataeibacter hansenii TaxID=436 RepID=D5QC17_KOMHA +--TLAQDVAKTVSGQPGSFAVYAAMSGQRPQV-CLNCTDYINAASTMKLFVMDAAYDMFT +RGTLQPQETIVVHNRSLVGTRSFSYAQIGRPVTVSELVRVMIQYSSNLATNLMVERI-GV +PYIHAVMHAQHLKGVRFGRMIEDYDAN-DKGIRNEMTAKGLGMFMQKLDQGKIVGPAQSA +AMIDILRGQTF-NDMIPPGLPPGTPVAHKTGWVD-GVRNDAGIVFLPDGRHYILVMLTKS +LP-DEAAGIRVLNGISRQVYGHf +>[subseq from] serine hydrolase n=1 Tax=Komagataeibacter hansenii TaxID=436 RepID=UPI00094FCC51 +--TLAQDVAKTVSGQPGSFAVYAAMSGQRPQV-CLNCTDYINAASTMKLFVMDAAYDMFT +RGTLQPQETIVVHNRSLVGTRSFSYAQIGRPVTVSELVRVMIQYSSNLATNLMVERI-GV +PYIHAVMHAQHLKGVRFGRMIEDYDAN-DKGIRNEMTAKGLGMFMQKLDQGKIVGPAQSA +AMIDILRGQTF-NDMIPPGLPPGTPVAHKTGWVD-GVRNDAGIVFLPDGRHYILVMLTKS +LP-DEAAGIRVLNGISRQVYGHf +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus tucceti TaxID=238012 RepID=UPI000708ED30 +----------NLSGIKGDTTAYYYNLDDDTTA-SYDAKTPQRAASDIKLYIMAAAFQKIA +DGDISLNDRYELTNDDKVGGTGVTQNMQAGELTYRDLIDYMITKSDNTAANIITKEVGGM +SAVNDEIEKLGLDNTKMERMLMDQD-ALAEGKDNKTTSYDLAIFMKKLYRHDVVSAKYDK +EMMSVLSNTSN-HSKIPAEINTNVDVYNKTGEYDYGVENDAAILKRDNKA-FVLVVMSQN +GDSD--EQKDAMGSLGK------ +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus radiopugnans ATCC 19172 TaxID=585398 RepID=A0A5C4Y515_9DEIO +------------QGYGGEVGLRICDLVGQELF-ALNAARVFPAASTIKVPLLVLALEWAQ +TGRLRLEDRVTLQAADRVPGAGVLHELGPGLLSWRDVLTLMIVVSDNTATNLLIDLL-GV +ETVNTWLEARGWSQTRLVGGLERRNAAQRRGERNCTSALEQTDLLGRLVRGELLDEVHTA +LALDILERQQL-RDVIGPGLPRAYRLASKSGELD-GVHHDVGILYTP--RPLVVALLSEG +GAD-------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Aquiflexum balticum DSM 16537 TaxID=758820 RepID=A0A1W2HBA1_9BACT +-qSLQRFLESEVKDFKGDVGIYVYNLKTNEEV-AINADTIFPTASIVKVPILVGVMDKIE +KGELEYHQKLVYRDSIKYGGSGLMQFFQDSVTELSVLMSLMITYSDNTTSLWCQALAGGG +ERINEIMEGLGLEHTRVNSRTPGREEIWKVYGWGQTTPREMAQLLVKIRRGEVISRKASE +RIYRLMSNIFY-DEYSLSAIPPYVQTASKQGMVN-ASRSELVMVNAPKGD-YVFYIATKN +NEEEDNAAYELQRKVSRILWEWf +>[subseq from] Serine hydrolase n=2 Tax=Candidatus Cryosericum odellii TaxID=2290917 RepID=A0A398DDC3_9BACT +--NWQEQVRALFGSAQGKFGVYAA-TATTPLF-EYQASSIFPSASTIKVLIMAELLRQVE +AGTHSLSEHPALPT-APTGGCGILEFLSSDYPDLMDLLHFMICSSDNKATNVLIHLT-GM +DAVNQLAVDIGMTNTRLRRFMMDTESM-QQGIDNTTSPADMGRFFKLLACNELVSSRASA +TMKTILGRQQF-SHIMMLFLPEGIQVEHKTGGLP-GSVLDVGLVYSA-RDPLILCLMATQ +LAN-NGEGAVILGKVAEIIYR-- +>[subseq from] Serine hydrolase n=1 Tax=Muribaculaceae bacterium Isolate-007 (NCI) TaxID=2489217 RepID=A0A4Q0INX5_9BACT +--HIEERLATYIAAQDARIGVAVI-IDGRDTI-SVNGNRDFPMLSVYKFPQAMAVADYCM +KNGVGLSDTISIRGDEMKEWSPMRDRYGVGDLPLSELLEYSLRDSDNNACDILFRLIGGT +HVADSLMKAMDFDDIVIASTEDEMHRDIYLCYQNRSTPIAMAGLFDRFYRQEMRHSPLHE +AIGRIMMTCTTGNRRLPAPLPTNAVIGHKTGTGDVNSQ---------------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1H0MSE3_SELRU +--ALAEAITGLSNADSTRYSLYAAYPQESREP-YIYQSEPMRSASMIKVFLLADAMEKVR +DGQLALNTGITLHSKDKVGGAGVLCGYASGTLPLDTVLRLMITESDNTATNLIIDLL-GM +DDINAYIRRNGYNDTTLARKMMDFAA-VNAGRDNYTSVTDLGNIFQRIYNHECVGYEQDE +IMLSYLKGQTD-TECFPAALP-GAVIAHKTGELG-GLYDDGGIIYQNGRA-IILVIMTEH +YSN-RYRAIETMKAMAQSVM--- +>[subseq from] Beta-lactamase n=1 Tax=Deinococcus geothermalis (strain DSM 11300) TaxID=319795 RepID=Q1J1L5_DEIGD +-------------GYVGEVGVLITDLAGRELY-ALNPDRVFPAASTIKVPLLLLALSEAQ +AGRLDLSGRVTLRAEDRVPGAGVLHELMPGLPTWQDLLTLMIVVSDNTATNLVIERL-GL +DRVNDWLGERGLSGTQLVGPLERQNAAQRRGERNRTTARDQVALLGALVRGELLDRSHTG +LALSILERQQL-REILGRHVPCDYRVASKSGELM-GIHHDVGVLFTP--RPLIAAVLSQG +GL--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A174QS40_9CLOT +---IEKRIEAELMSYDGTMGIYADDLH-GNII-AIGADEAFETASTIKTYILACLFDQVE +KGKASLEDMVEFKEEHTVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL +DTINACIRGLGCRDTVLYNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPESDA +KMLEIFKKQHY-NSMITKDFPAVVTVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNRK +FSDAAHPATVFGARVSRLLFDQf +>[subseq from] Uncharacterized protein n=3 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A358IF26_9BACT +-dSLQSRIAARLDRLDAMSSIYAKHIPTGREI-AVRADHPMNTLSVIKIPVMVKAFQDNA +SGRLDFGERYTIGPNDMRRGSGLIQTFEPGLPTLRSLVTQMIITSDNTATDMVIKAV-GL +NRVNALLQSEGFSQTRLKATTGDLFRAFEGDSTGKTTAREMGNLLEQILNAELADEEASA +EMIAMLTRQFY-TSRLPQRVRQGVSVAHKTGDWPPIAGNDVGILFYEGG-PSIVSVFTNQ +NTGDFFDLEATLGLIAEDIVEAw +>[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus modestisalitolerans TaxID=1457219 RepID=UPI0010FA3E5F +--AVRQRVQSQVVNLAGTTSVAVRATSGRGQV--VHNNRQQRAAGLAELFVLAAVYQQAQ +TGKLTLTQRVTLQAQDRVAGTGQLQTMPAGSFTVANLAKRMIVDSDNTATNLLIDQLGGV +TATQRVIQQLGFTKTELNRKMMDTS-ALKAGRDNQTTVNDVAALLRQLYRGTLVAKTADQ +TMLKLLKQTQ-GPSNLGANLPSSATVYHLAGTYSYGVQNEAAIVQNRHGA-FVVVMLAEN +GQAQ--AQTKRMRQ--------- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00101B745B +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGVLKALPRVTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKDLGLKKTLLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNFLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces aureocirculatus TaxID=67275 RepID=UPI000561A1E4 +-----TRIQEAFAEAGVTGKLHALDIDSGAEL-GTGADQAVVTASVHKLCVLITLHEQAA +AGLVDLTEQVECPPDGRASGPTGLSAMLDPVMSLRDAAYLMMAVSDNTAAELCLSRV-GL +DAVNATTARLGLTRTRALHTFRAMFEALDPARSNHSTARDMTRLLRALWRDEACTPEHGA +AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA +ARATLPSADAVIGTAARIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BA60B85 +------------------NGLIRIHIEGKESI-RINSFIQQRAASTIKLLLAIEAFRQID +AGILALTSAIQRMEKNTVGGAGVLKALPQLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGSLLRKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. 66b TaxID=1945511 RepID=UPI0009BA88E2 +--SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +DNIVATLRGLSLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HEHRAPKIDASIGTVGRIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Nubsella zeaxanthinifaciens TaxID=392412 RepID=UPI000DE335F3 +--KLNKMINELAKGFNGDVGIYVKSLKTGKIA-TLNADSIFPTASMIKVPITCGIFDKIE +KGELNYNTQLVYKDSLLYAGEDILGSFKSGEIWLAKVLMLMITTSDNTASLWCQSLAGTG +VAINQLMEKYGLQYTRVNSRTPDRQANQRKYGWGQTTPREMATLLTLIREGKMISPSASE +RIYRNLIRIYF-DKEALSEIPPYVQVASKSGAVN-ASRSEVVLVNAPHGD-YVFCVITNN +QKRYENEGEVLIRSLSKMLWNYf +>[subseq from] serine hydrolase n=1 Tax=Cyanobium sp. Copco_Reservoir_LC18 TaxID=1328305 RepID=UPI00135B8038 +----SQQWARLAAQKGLTASGFLLVLDDGRYA-ELQPDLPLSAASSIKVPILLAGLEDLD +RGKVRWNEPMPLTKEVVGGGAGWMAKPLGTRFPFFEAATEMIRVSDNTATNLLIRRLGGK +TELNGRFRSLGLTATVVNNWLPDLDGT------NTTSSRDLARSIALVDTGDKLTPRARD +LFREIMGTSRT-NTLIPELLPEGITVYNKTGDIGI-AYSDTALIQLPNGQRAVLAVMVKG +PFND-PRSAELIRSMAGAVTK-- +>[subseq from] Serine hydrolase n=1 Tax=Komagataeibacter hansenii TaxID=436 RepID=A0A318Q142_KOMHA +--TLAQDVAKTVSGQPGSFAVYAAMSGQRPQV-CLNCTDYINAASTMKLFVMDAAYDMFT +RGTLQPQETIVVHNRSLVGTRSFSYAQIGRPVTVSELVRVMIQYSSNLATNLMVERI-GV +PYIHAVMHAQHLKGVRFGRMIEDYDAN-DKGIRNEMTAKGLGMFMQKLDQGKIVGPAQSA +AMIDILRGQTF-NDMIPPGLPPGTPVAHKTGWVD-GVRNDAGIVFLPDGRHYILVMLTRS +LP-DEAAGIRVLNGISRQVYGHf +>[subseq from] Uncharacterized protein n=2 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E6MMJ1_9BACT +-dSLQSRIAARLDRLDAMSSIYAKHIPTGREI-AVRADHPMNTLSVIKIPVMVKAFQDNA +SGRLDFGERYTIGPNDMRRGSGLIQTFEPGLPTLRSLVTQMIITSDNTATDMVIKAV-GL +NRVNALLQSEGFSQTRLKATTGDLFRAFQGDSTGKTTAREMGNLLEQILNAELADEEASA +EMIAMLTRQFY-TSRLPQRVRQGVSVAHKTGDWPPIAGNDVGILFYEGG-PSIVSVFTNQ +NTGDFFDLEATLGLIAEDIVEAw +>[subseq from] serine hydrolase n=1 Tax=Streptomyces coelicoflavus TaxID=285562 RepID=UPI0013DC9ED7 +--ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQAVCTASVHKVCVLVTLHELAA +AGGLDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPAEYGA +AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEIGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Actinomadura fibrosa TaxID=111802 RepID=UPI00104138D6 +-----------FRDAGVTGCLHAVDVDTGREV-ALGADEPVVLASVFKVPLLVAFHRQAA +EGVLDPAEQVTLRPEDRTPPTGVSALLDEVRMSLRDLACLMITVSDNASADALLERV-GL +DAVNATAAEFGLTGTLVLDSGREMLDALDPARTGRSTPRDMTRLLGLVWRDEAAPPAECA +AMRRILGLQVW-PHRLASGFPDDVVVSGKTGTVPT-IRNEIGVVEYPDGGRYAVAVFTRS +ALAVLPQADAVIGTAARLAVE-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 (Fragment) n=3 Tax=Acinetobacter baumannii TaxID=470 RepID=B5B4Y5_ACIBA +----------------------------------------------------MLVLHQVD +QGKLDLNHTVIVNRAKVLQWAPIMKAYQGDQVPVQQLLQYSVSHSDYVACDLLFELVGGP +SALHDYILSMGIKETAVVANEAHMHAHHHVQYQNWTSMKGAAQILKKFEQKTQLSETSHA +LLWKWMVETTTGPERLKGLLPAGTVVAHNTGTSGTAATNDLGIILLPDGRP--------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000D51CA77 +----AGRLHAAFADAGVTGLLHAVDIDSGAQV-GAGADQPVCTASVHKVCVLVTLHELAA +AGEIDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAALLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGEMLAALDPARTNRSTPRDMTRLLTAVWRDEACPPQYGA +AMRRVMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT +ANATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=2 Tax=Saccharopolyspora dendranthemae TaxID=1181886 RepID=A0A561U6W1_9PSEU +---AEQRMRDVLADAGAQGWVHAVRLGGGHQL-GIGADELVVTASVYKLPLLVALARAFD +SGVLDPREPIRLEPTSCTPPTGVSIFQDPVRMSWRDLAASMIAVSDNAAADVILGAV-GL +EAVTAALADLGLERTRVVGGTAESHAAYDPSYASATTPHEMTRLMELIWSDEAASPHQCE +FVRGLLGQQAW-MHRVRAGFPQGVRVAGKTGTIG-AVRNEVSVVEFDGEAPVAVAVFTLA +ARADLPRVDAAIAECARIAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium lactis TaxID=797291 RepID=A0A1H5UIF9_9SPHI +-kALEKKIHAAIAEFQGEFAFYSKHLKQHKEV-AINADELYPTASVVKIPILVGVFQKIA +NGELRLDQQLTYRDSRAYGGSGIMQFYKDSTTDLATLIGLMLSYSDNVTSIWCQELAGGG +LAINPIMESLDLKYTKVNSRTAGREEDWKKYGWGQTTAREMSQLLEKIRLGKVISPQYSD +KMYRFLKNQFY-NGRSLSQFPAEINCISKTGSLED-VRTETVLVNAPHGD-FVFTLLTKN +NKDNTNEAEILTRKIANIIWNHy +>[subseq from] Uncharacterized protein n=1 Tax=Leptolyngbya foveolarum TaxID=47253 RepID=A0A2W4W4Q5_9CYAN +--KLQAQLDKLTTLYELQFKAFYIDVDTGDYV-DIDGRGAIAAASTIKLPILLAFFEEID +KGNIDPNQTIAILPEQIAEGSGDMQISPPGTFTAIEVATQMIVNSDNTATNMMIDLLGGA +EVLNERFVSYGLEETRLNNPLPDIEGA------NTTSARDLVHSM-LLVQSDRLKMRSRD +RVLNILERTEN-KRLLPAGLEQGALTYNKTGFIDK-MLGDVALVDLSNGKRYVISVLVES +PDND-GRALDLIHGISERTF--- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. BK208 TaxID=2512150 RepID=A0A4R7JCJ4_9ACTN +--STAARLNAAFTDAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVALHELAA +AGALDLTERIECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLVRRV-GL +DAVNRTTARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Streptosporangium amethystogenes TaxID=2002 RepID=UPI0004C7A2B7 +---TEERIAEIFAAAGLDGHLHALDITGGREV-GVRADEQVVIASIFKVLLVLEFARQAA +AGQLDPAERVLVTAEDRLGGWGTAGCADDMEMSLRDLAHFAMSVSDNTAADLLMRRV-GL +DTVQMLAAELGLVRTRVIGGPRQVLEVFDPGHTTSSTAREMTRLLGLIWRDEAGPPQACA +AVRDYMARQIS-WTRIASGFPPEVRVAAKTGTLP-GLHMEVGVVEYPRGGRYAVAVFART +EQLHATRRDLAIGQAARVAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_40CM_4_68_4 TaxID=1805077 RepID=A0A1Q7HSH5_9CHLR +--DLVQQLDQLSASFPGGVGLWIADPNATRPLySHNADEHVITASLYKLGVLMEAERRVD +TGELKYSDPMTITEEDVMLDGSF--EGAGTDLTIDQALEAMITISDNGSARALWRLL-GP +ENIDVTLQKAGITDFHVQLTD---------YEDNVATPRAIGQFFTLLATRKLISPAASD +RMLARLERQEI-NDRLPAALPDNVVVAHKTGNLV-GAVHDAGIIYTPSG-PRVVVAMTWD +AY--DEEANALIANIGAIVYS-- +>[subseq from] Beta-lactamase n=2 Tax=Fibrella TaxID=861914 RepID=I0K5M1_9BACT +--RLTQQLADALRGFRGDVGVYVRHLKTGKTV-AINADSTFPTASTIKIPIMIGLFDQIQ +KGTVSYEQELVYRDSLHYDDGIVGSLRDGAKIPLSQVVMLMETVSDNTGSLWCQALAGGG +TAINAWLDANGFPNTRMNSRTPGRKEFQARYGWGQTTPRELASLLTYIRDGRAVSPDASD +RMYRNLCRQYW-DHDGLSQLPANVKVASKNGAVNR-SRSEVVLVHAPHGD-YVYCLMTKN +QQDETNEGSTLLRTVGALLWQHf +>[subseq from] serine hydrolase n=1 Tax=Komagataeibacter hansenii TaxID=436 RepID=UPI000789B239 +--TLAQDVAKTVSGQPGSFAVYAAMSGQRPQV-CLNCTDYINAASTMKLFVMDAAYDMFT +RGTLQPQETIVVHNRSLVGTRSFSYAQIGRPVTVSELVRVMIQYSSNLATNLMVERI-GV +PYIHAVMHAQHLKGVRFGRMIEDYDAN-DKGIRNEMTAKGLGMFMQKLDQGKIIGPAQSA +AMIDILRGQTF-NDMIPPGLPPGTPVAHKTGWVD-GVRNDAGIVFLPDGRHYILVMLTKS +LP-DEAAGIRVLNGISRQVYGHf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces coeruleorubidus TaxID=116188 RepID=A0A5J6I7K1_STRC4 +----LTRIHAAFADAGVTGRLHAVDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA +AGFLDLTEQVECPPEGRTAPTGLAAMLDGARLSLRDLAYLMMSVSDNAAADLLLARV-GL +DAVNRTTARLGLTGTHAVHTFGELLAALDPARTNHSTPRDMTRLLAAVWRDEACTPEHGA +AIRRVLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT +ARTSQPAADAVIGTAARLAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CB09001 TaxID=2083284 RepID=A0A346C2L2_9ACTN +----AARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADRPVCTASVHKLCVLVTLHELAA +AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL +DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNHSTPRDMTRLLGAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Cyanobium sp. TaxID=2164130 RepID=A0A326QE10_9CYAN +---LSARWKALAAQKDLKVGGFLLVLDDGRFA-QLNPDTPLPAASSIKTPILLAALEDLD +RGKLRWGEPLPLTKEVVGGGAGWMANRPGTRFPFYEAATEMIRVSDNSATNLLIKRVGGK +LAINARFQALGLPATVVNNWLPDLEGT------NTTSPHDLARSIALVDTGAKLSPRARD +HFRTILGTSRT-NTLLPAGVLKGITVLNKTGDIGI-AYSDAGLIELPNGQRAVAAFMVKG +PFND-PRSTDLIRAMAATM---- +>[subseq from] Serine hydrolase n=1 Tax=Halorubrum sp. 48-1-W TaxID=2249761 RepID=A0A329T8M5_9EURY +--DLARAIDSIADRFDGRLGVFLCVPRGADAFhSRNADEEFVAASVIKLPILYALYEAYD +GELDRLGEPRPIAAENRVGGSGILHLFDDPTSTLEDLARAMIAISDNTATNQLIDEL-GA +DRIERTAARLGMDDTRLRRKMMATLGQLEGRPANATTPADCARFFADLVHEATLSAPAYE +RLRVPLDEQKD-RSLFPRYLPYRTPIAHKTGGLPT-AALDAGVLRSADASPLVFSAFATR +AENG-GDAGDAVAAVGEVAFE-- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A537I206_9BACT +--KLFKKVSEEINGFNGDIGIYVKNLRTGKTI-AINADTIFPTASIVKVPIMIGVVQKLF +TGEITYDSAFTYKDSLLYAGADILGSFKTDEIALKKLLMLMLTTSDNTASLWLQSIAGTG +TRINELLDSFGLKNTRINSRTPGREEYRSKYQWGQTTPYEIGTVLEKIYKNEIFSKELCD +RMMRMLGRNFWDEDEAISQIPPYIEVFSKNGCVN-AVRSEVTIVNAPHN-PYVFSIFTKN +NKTHENEAWTLARKISRLLWDYf +>[subseq from] Uncharacterized protein n=1 Tax=Leucobacter sp. G161 TaxID=663704 RepID=A0A0W7WBN7_9MICO +-qSVSEAIAEAATAAGVSVFAHARDLDSGAEV-GYHFDEPTVTASVFKVPVLLEYVRQVA +AGELDPAQRILVSPASVTRGPTGLSVFSDETWSLRDIATSMITVSDNAATDIVVELV-GV +DRVNATMAELGLPGTQLVGDCATLFAASTPAKTNRSTPREATRLLELLWTDAAATPAACA +EARRILGLQVW-PHRLSSGFPDDVKISGKTGTLGI-VRNEIGVVEFADGRRHAIAVFLRS +TESRNPKADRVIGTVARLLSD-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536ATC9_9CHLR +--ELVQHLDQLVGSFPGGAGLWIADPNASKPLySHDADEPIITASLYKLAVLAEAERRVD +AGQLHYSDIITIENEDITEDGSF--EVAGTELTLDQALEAMVTISDNGAALALWHVL-GA +DNINATLRNVGINDFHVFV--------AYGEDDNIATPRAIGTLLTLLAKRQLISAAASD +RMLARLERQQI-NDRLPAELPEGVVVAHKTGNLP-GLTHDAGIIYTPSGP-RVVVAMTWD +AY--EADAYAFIANVGSIVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A651HE47_9BACT +-eRLQNELEAVVHRFDGVAGIHVVDLTDGRRF-DVRGDLIFPQASAIKITILLELFRRAE +TDPGLLRKRVELTEAVRTGGSGVLNILTDGGLSLEDHAIYMIVYSDNTSTNVLLDEL-GM +AEVNALAASLGAPQTIFQRKMIQPEAS-ARGDENLSTPREAARIMERIAACELMSAAACA +RVTEILALPKGGP--ARAAVPASIPIAFKPGGIT-GVATVWAVVQLPGR-PYVLSVMANY +GG----DGGSVVREASEAAYSYf +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3B9Z6X2_9CHLR +--RLAEEVVSVLRGRDELVSIAAVHLLDGTGV-ALNADDVVPPASLFKLNILAETYRQIE +RNRVKLAQMITILPEDAAPGAGILQDRIGEAVSVGEALSLMIGISDNTAAFALLRTI-SS +RKLNECTRALGMLRTWFYVDER----------PDETSAGDVVTILRAIIDGTIASPRGTD +QMLELMTQVQP-SAWIRSGLPPGTRLAHKSGQLE-GIRNDAGIVFGPTG-PYALAVLTHD +LY-DPAVGEQIITAVTRVVHRYf +>[subseq from] Putative Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces afghaniensis 772 TaxID=1283301 RepID=S4MRG0_9ACTN +----LDRIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA +AGLLDLTEQVECPPESRTTPTGLAAMLDGARLSLRDLAYLMMSVSDNAAADLLLARV-GL +DAVNRTTARLGLTRTYAVHTFGELLAALDPARTNHSTPRDMTRLLAAVWRDEACIPEHGA +AIRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT +ARTSQPAADAVIGTAARLAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. MED-G68 TaxID=2267259 RepID=A0A4V8DEL2_9SYNE +--ALSKRWEALAAQDDLQVSAFMLALDDGRYA-QLNPDTALPAASAIKTPILLVALEEID +AGRLSWNEPLTLSKTVVGGGAGWMAKPLGTRFPTHEVATEMIRISDNTATNLLIERVGGQ +EDLNARFTSLGLSATKVNNWLPDLKGT------NTTSARDLARAIALVDTGEALSIRGRD +LFREVMGTSVT-NRLLPGGLLKGYRVFNKTGDIGI-AYADAGLIELPDGRRAVAAFVVKG +PFN-DPRSTELIRNMAAAM---- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A1Q8URJ5_BACME +------------------NGLIRIHIEGKESI-QINSFIPQRAASTIKLLLAIEAFRQID +AGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSVFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Spirosoma sordidisoli TaxID=2502893 RepID=A0A4Q2UTJ2_9BACT +-sTLEKRLQTALTGFRGDVGVYVRNLRTGQTV-AINADTLFPTASTIKIPIQCGLFDKIH +QGELTYGQVLTYKDSLRYGDDIVGSLKDGAKIPLSEVVMLMETVSDNTASLWCQALAGGG +AAINAWLDKNGFPQTRVNSRTPGRKGYWSQYGWGQTTPRELANLLVYIREGKAVSPDASD +EMYRNLGRQYW-DNDGLSQLPPEIKTAAKNGAVDR-SRSEVVLVHAPHGN-YVYCVMTKN +QKERSNEGFTLLRNVSAILWQHf +>[subseq from] Uncharacterized protein n=1 Tax=Pontibacillus yanchengensis Y32 TaxID=1385514 RepID=A0A0A2TAX5_9BACI +--SLEKKVTNIVSTLNAKASVVIRT--NYGTI-AINEKEIMPAASVIKIPIMMEAFRQAR +TEGGDLSAPVTIPQHNKVGGAGVLQFLSQDTFSLYDLVKLMIIVSDNTASNAVIRSV-GM +EAINRMIEELGCWNTKLRREFMNLKAQ-GQGFDNTTTAEDMVNLLEQLALHD-------R +EMVEILKGQQLTSQLPAYNTYEDLEIANKTGELD-GVQHDVGMFVDSYQ-SVYVAVLLNE +VG-EAVEAQRAIADIGHQVMQY- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7EA23_9BACT +--ALRKTLDSIADAHHGIVGYSVIDLETGARI-SRHGDETFPTASLIKVAILATVYDLVA +KGQLSLDDPLTVLKIDQVPGSGIVQFHNGTVLTIHDAAWLMSTISDNTATNLLLDRI-II +RRVWAKMDSLGLQHTRVHSKSFLRNSSVAMDSSGVTTPNEMAHLFELMAQGKTVNPSADS +TMLDILEHNGT-DFMLQRYA-GGARAAHKDGETD-AVRTECTLWYLRNR--VVACVMTKE +NKDQDNEPQLTMANMGLAIIN-- +>[subseq from] Serine hydrolase n=2 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A413X4V9_9CLOT +---IEKRIEAELMSYDGIMGIYADDLH-GNII-AIGADEPFETASTIKTYILACLFDQVE +KGKASLEDMVEYKEEHTVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL +DTINACIRGLGCRDTVLYNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPESDA +KMLEIFKKQHY-NSMITKDFPAVVTVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNRK +FSDAAHPATVFGARVSRLLFDQf +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF92C1B +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIVVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMLDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLKIQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=candidate division KSB1 bacterium TaxID=2172550 RepID=A0A3A0DY23_9BACT +---LTKKVLQAIDGFKGEVGVYVRHLKSGKTV-MIRADELFPTASMIKVPILLTAFQKIQ +EGELDYHGEQTYRDSLLYAGEDILGSFKDGEIKLSKVIMLMITTSDNTASLWCQKLVGTG +TAINEWLQAHGFSQTRVNSRTPGREADREKFGWGQTTPREMAELLVMIREGRAVSLDASE +EMYRTLTRIYWN-GEALSQIPPFIQAASKQGAVNR-SRSEVVLVNAPSGD-YVFCVITKN +QEDEDNAGYVLLRNISRLLWDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Cyclobacterium halophilum TaxID=1416801 RepID=A0A1H6T4C9_9BACT +---FTQKLEEEMANFGGETGLYVEHLASGEIF-AIRADSLFPTASVIKVPIMVGIFKQIH +EKKLELDTALLYRDSIRYGGSGLMQYFKDSTTDLATLLSLMIGYSDNTASLWCQELAGGG +QEINKLLDSLGLEHTRVNSRTAGRQEAWEKYGWGQTSPREMVSLLRMIRHEELFSPELSQ +KMYRLMSNVIY-DNYALSAIPPYIQTASKQGMVSS-SRSELVMVNGPSGD-YVFYIATKN +NRDEDNEAYRLQRKLSGMLWNYf +>[subseq from] Beta-lactamase enzyme family protein n=1 Tax=Rhodococcus sp. MTM3W5.2 TaxID=1805827 RepID=A0A1P8YG19_9NOCA +---------------------------DDDVV-SVGADELVVTASVYKLPLVVALCRAFD +AGSLSPTARVRINPADCTPPTGVSTFRDPVVMSWRDLALSMMTVSDNAAADLILGRV-GL +DGIDRVLAELGLTRTRIIGGTADVHRAYDPAFTSATTPREMTSLLDAIWTDRAVSAVQGE +FIREVMAGQIW-PHRIRSGFPAGVTVAGKTGTIG-AIRNEVAVVGFPGETPVAVAVFTRA +ARADLPVVDRAIGRAAHIAVT-- +>[subseq from] Beta lactamase n=1 Tax=Kutzneria sp. 744 TaxID=345341 RepID=W7SXL8_9PSEU +--SVAARISAVFRSAGAQGFLHAREVGDGPEI-CLGADDPVVLASVFKVPVAVAYAREVA +AGRLDENERTTVTSRYRVGGIGTAGCADDVTMTWRDLALFMMTMSDNAATDVIFHRV-GQ +AAVDQVLADLALHRTRLIGCCEDLTGVLDPTRTTASTPRDITTLLDAIWTDVAGPPEACE +LVRDIMSRQIW-PHRLGSGFESDVEIAAKTGSLP-AIRNEAGVVTYPDGRRYAVAVFTRA +DSGRQPKVDAAIGRAARLAVDE- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. BS55D TaxID=2055943 RepID=UPI00103AA83A +--ALSQRWQELASQKDLQVSAFLLLLDDGRYA-QLNPDTALPAASSIKTPILLVALELLD +AGTLSWNEPLTLTKTTVGGGAGWMASPIGTRFPTHEVATEMIRVSDNSATNLLIERVGGK +EELNARFNALGLSATAVNNWLPDLEGT------NTTSARDLARSIALVDTGETLGPRSRD +LFREVMGTSRT-NRLLPGGLLEGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFVVKG +PF-NDPRSTELIREMAAAM---- +>[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus hitonicola TaxID=435880 RepID=A0A1I2T1C5_9BACT +--SLQQKLELIARDFKGELGIYVKNLNTQESA-QINSDSIFPTASIVKIPILLGIFEKIE +KEELQFHQSLIYRDSIKYGGSGLMQFFNDSTTDLRTLVALMLSYSDNTTSLWLQGLAGGG +ESINPLLEKWGVQHTRINSRTPGREKDWEIYGWGQTTPKEMAQLLEGIYKGTIFGRSSSE +QMTRLLSNSYY-TEYALSQIPPTINVLSKQGMVN-ASRSEVLLVNSPAGD-YVLSFFTKN +NEDEDNEAWKLSRKVSHEVWNHf +>[subseq from] Uncharacterized protein n=1 Tax=Rubrivirga sp. SAORIC476 TaxID=1961794 RepID=A0A271JEY3_9BACT +--ALQARLDALADGFNGVVGVYLRHLPTGREA-ALRPDDLFPTASIVKVPILVGVFEQIE +AGTLALDTELTFRDSLRYGDSGFAQLRDSSTVYLHSAVEQMLAASDNTASLWLQGMV-TG +EAINAWLAAEGFEGTRVNSRTAGRRGDWERYGWGQTTPREMAELVRRIVDGEAVSPAADL +EMHRLLTRTHY-DDEAIAALPPSVQVASKQGAVSQ-SRSEVLYVHAPSG-PYLLMVVTKE +QAAPDNAGYDLIRAVSRLAWETf +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A358ECH6_9BACT +-dSLQSRIAARLDGLDAISSIYAKHIPTGREI-AVRADLPMNTLSVIKIPVMIQAFQDNA +SGRLDLGERYTVGPNDMRRGSGLIQTFEHGLPTLRSLVTQMIITSDNTATDMVIKAV-GL +DRVNALLQEEGFSQTRLKATTGDLFRTFEGDSTGRTTAREMASLLEQILNAELADEEASA +EMISILTRQFY-TSRLPQRVRQGVSVAHKTGDWPPIAGNDVGILFYEGG-PSIVSVFTNQ +NTGDFFDLEATLGLIAEDIVEAw +>[subseq from] serine hydrolase n=1 Tax=Rubrivirga sp. SAORIC476 TaxID=1961794 RepID=UPI000BA8F949 +--ALQARLDALADGFNGVVGVYLRHLPTGREA-ALRPDDLFPTASIVKVPILVGVFEQIE +AGTLALDTELTFRDSLRYGDSGFAQLRDSSTVYLHSAVEQMLAASDNTASLWLQGMV-TG +EAINAWLAAEGFEGTRVNSRTAGRRGDWERYGWGQTTPREMAELVRRIVDGEAVSPAADL +EMHRLLTRTHY-DDEAIAALPPSVQVASKQGAVSQ-SRSEVLYVHAPSG-PYLLMVVTKE +QAAPDNAGYDLIRAVSRLAWETf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-337 TaxID=1463900 RepID=UPI0004C535AF +----PARIRAAFAEAGVTGWLHALDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHQLAA +AGALDLGEHIECPSAGRTPGPTGLAAMLDPVMSVRDVAYLMMAVSDNAAADLLLGRV-GL +DAVNRTTRRLGLTGTHAVHTFGELFAALDPARTNHSTPRDMTRLLGAVWRDEACTPEHGA +AIRRILGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A651HDK6_9BACT +-eELESRIRAQLDALDARTALYAKNLPTGREV-AIRADEPMNTLSVIKLTALVQAYREAE +AGRLELDARHPILPEDLRRGSGILQTFDPGLPTFRDLLTQMIITSDNTATDIVAERL-GL +DRVNAFLESEGFQETRFRMTTGDLFRALEGDSTGRSTARETGRLLEGIHEGTWTSRENSE +EMLAILRRQLS-SSRLPRYVGFEASVAHKTGDWPPFGGSDVGILFHEGG-PTVVAIYTGQ +NRGDFVELERKLGRIAVELVQG- +>[subseq from] Serine hydrolase n=2 Tax=Bacteroidetes TaxID=976 RepID=A0A1V0DG10_9BACT +--ALQARLEHLVEGFRGDVGIYVRHLPTGREA-AIQPDTLFPTASLIKVPILLKTFDAIE +QGMLDYHQPLVYRDSLYYPGEDLIGALKDSSIALSKVVMLMITTSDNTGSLWLQGLVGGG +TAINDWLAAHGFEHTRVNSRTPGREAAREVYGWGQTTPREMAEMLVMIREGRAVSPAASE +EMYRVLTRIYW-NDEALSQLPPTVQAASKQGAVSR-SRSEVVLVNAPHGD-YVFTVITKN +QETHDNEGYVLLRDVSRLLWQYf +>[subseq from] Serine hydrolase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A4Z0VWY0_9ACTN +----RDRIRAAFAEAGVTGWLHATDIDSGAQL-EVDADHPVVTASVHKLCLLVALHQRAE +AGHLDLAEQTECRPEGRTPGPTGLAAMLDTALSLRDAAYLMMSVSDNAAADLLLARV-GL +DTVNESTRKLGLAHTHAAHTFGEFLAALDPARTNRSTPRDMTRLLRAVWRDEACSPRHGA +AIRRLLGLQVW-PHRLASGFPDEVHVAGKTGSAPT-LRNEVGVVEYPDHGRYAVAVFTRA +ASPSLPAADAVIGTAARIAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces atratus TaxID=1893 RepID=A0A2Z5JRF9_STRAR +---------------------HALDIDSGAQL-GVEADQLVCTASVHKLCLLVALYDRAA +AGDLDLTEQVECSSDPRTPPTGLAAMLDAARLSLRDLAYLMMAVSDNAAADLLLARI-GL +DAVNGATARLGLDATRAVHTFGAMLAALDPARSNRSTPRDMTRLLRAVWRDEACLPEHGA +AIRRVMGLQVW-PHRLASGFPDDVLVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +ARATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=2 Tax=Gemmatimonas aurantiaca TaxID=173480 RepID=A0A3D4V9D5_9BACT +--SLRRVIDSLADAHRGVVGYSITNLETGEHL-ERRGDETFTTASLIKVPVLVALFDLAE +QKQLTLDDPIVLTEIDKVGGAGQLQFLRTPLLRLWDVAWLMTTLSDNTATNLVLDRI-KI +RRVWQKMEALGLPHTKVHSGSMTRIGTVAPDSSGVTTPNEMARLFTLLAQGKAVSPSADS +TMLAILARNVDDAKLLRYAY--GVRAAHKTGDVDN-ARTDCGVLYLPAR--VVACVLTKE +NVDTDAEGNTVIGRIGAAIVAHw +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL F-5123 TaxID=1463856 RepID=UPI000694D63E +--TVEERVTRVFAEAGATVRLHAVDLHSDREV-GVAADEQVVLASVFKILLVLEFARQAG +AGQIDPRERVVLTAADRLGGWGVAGCADDVTMSLRDLAYFTMSVSDNTAADALLRRV-GP +DTVRLLAAELGLGRTRVLGGPRELLEALDPARTTSGTARDVTTLLRLVWQDRAGPAAACA +WVRELMSRQAF-RHRLASGFPDDVRVAAKTGTLP-GHHIEAGVVHYPDGGRYAVAVFAGT +VGPFQVAVDRAIGRAARVAVE-- +>[subseq from] Beta-lactamase family protein n=1 Tax=Synechococcus sp. (strain WH7803) TaxID=32051 RepID=A5GM59_SYNPW +--ALSDRWKQLAAGQDLTVSAFMLVLDDGRYA-QLAPDTALPAASSIKTPILLVTLEELD +AGKLSWNEPLQLSKAVVGGGAGWMAKPLGTRFPTHEVATEMIRVSDNTATNLLIERLGGK +EALNARFNALGLSATAVNNWLPDLKGT------NTTSARDLARSIALVDTGEALSIRSRD +LFREVMGTSVT-NTLLPKGLLRGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG +PFND-PRSTELIRKLAAAM---- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A6A0IDT8_9BACT +--ELSARLEALARGSGGRMGFVALHLESGRRY-ERLADEVFEGASVVKLALLVEAVARHR +EGTLDLSDRFPLTPQATAAGSGILDELQPGLPTYRDLLRLMITYSDNTAANVFVDRF-GA +AAVNSRMERLGFAGIRLGGRIPDREPRWKGLRLGWMTPRDTVELYRRIAERSLVDPEASR +LLLELLAWPKSLDRLFRTFRDEGVSWAGKSGTMR-GIRGDSGILTTRKGT-FVLAAFVDG +VDDDGPRANTAMAEAAREVVESw +>[subseq from] Serine hydrolase n=1 Tax=Salegentibacter mishustinae TaxID=270918 RepID=A0A0Q9ZBJ1_9FLAO +--ALQQKLEALVNDFKGDVGIYVKNLETDKEI-AINADTIFPTASIVKVPILVKIFDKIE +KGELNYNDTMVYSTDRIYGGSGLMQFYKDSTTDLRTLVALMISYSDNVTSLWNQELAGGG +EAINELMDEIGLEHTRVNSRTDGREKDWEKYGWGQTTPREMASILIEIRNRELISPAASD +EMYRLLGNSFY-QEYALSQIPPYVQAAAKQGMVNK-SRSELFMVNAPSGD-YVGYIATKN +NKEEGNEAWELQRKISALLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. Root147 TaxID=1736468 RepID=A0A0Q9G248_9BACI +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGVLRALPRLTINVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKEIDNYTCASDVVKCLREIYEGNFLQKSSRE +KIMRMLKMQKF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRVNET-YYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. 5K110 TaxID=2578104 RepID=A0A5R8LCQ2_9MICO +-eDIQAEIARIADEFSGEISVAATNLRTGEHV-EFNSREAFPASSVIKVPILVTLFHRAE +RGAVHLDRRLTMHEEDRVPGSGVLKLLSGGLLTVADAAALMIAVSDNTAANLVIDQLGGI +AEVNRAMTELGLHSIRLKNRLDFDVIGRDIAHLGVASTNDLDTLAQAIAHRTAFSPAVSE +ACEKLLSQQQYLDQVLRYVSVAPVVSASKTGFYP-GVRNDMGIVRFRGT-GFTYAACTRG +SDAPEDEGEVTNGRIGHLLLRH- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536HRQ3_9CHLR +--ELVQHLDQLVGSFPGGAGLWIADPNASKPLySHDADEPIITASLYKLAVLAEAERRVD +AGQLHYSDIITIENEDITEDGSF--EVAGTELTLDQALEAMVTISDNGAALALWHVL-GA +DNINATLRNVGINDFHVFV--------AYGEDDNIATPRAIGTLLTLLAKRQLISAAASD +RMLARLERQQI-NDRLPAELPEGVVVAHKTGNLP-GLTHDAGIIYTPSGP-RVVVAMTWD +AY--EADAYAFIANVGSIVYS-- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7HDA8_9BACT +--ALRNKLDSIADAHHGIVGYSVIDLESGARI-SRRGDETFPTASLIKVAILVTVYDLVA +KGQLSLDDPLTVLKIDQVPGSGVIQFHNGTVLTVHDAAWLMSTISDNTATNLLLDRV-II +RRVWAKMDSLGLQHTRVHSKSFLRISSSVKYGLGVTTPNEMAHLFELMAQGKAVNPSADS +AMLDILEHNTN-DMMLQRYLI-GARAAHKDGETDE-VRTECTLWYLRNR--VAACVMTKE +NKDQDNEPQLTMANMGLAIVNA- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces alboviridis TaxID=67269 RepID=UPI000515CFE8 +-----RTIRSLFDDAGVRGWLHVAELDRPSAHvVLDPDEQVPMGSVYKVPLMTAFCRLAD +AGRIDPSHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRAV-GP +EAVDRVCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPADIARLLRAIWTDEAASPASCS +FMRAAMGTQAW-AHRLASGFPDDVTVYGKTGTFGS-MRHEAGVVELADGSAYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] serine hydrolase n=1 Tax=Algoriphagus resistens TaxID=1750590 RepID=UPI0007168F78 +-nKLESAIQDLVASFHGDIGIYLEHLPSGNTI-EINSDTIFPTASIVKLPILLGVFDKIE +KGELHYHESLMYRDSIKYGGSGIMQFFKDSTTDLSTLLALMLSYSDNTTSLWNQSLAGGG +IQINQVMDQLGYKTTRVNSRTEGRERSWEKYGWGQTTPKEMADILVRLNAGELISTAASE +LMYRLLSNTFY-TDYAISGIPPGINVASKQGMVN-ASRSEVFLVNSPQGD-YVCAVFTKN +NVDQDNEAWILTRKLSNLIWNYf +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00064CAC3A +------------------NGLIRIHIEGKESI-RINSFIQQRAASTIKLLLTIEAFRQID +AGILALTSVIQRMEKNTVGGAGVLKALPQLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Komagataeibacter xylinus TaxID=28448 RepID=A0A318PF13_KOMXY +--SLSDEVAATVAGQPGHFAVYAALSGQRPEV-CLHCTDYINAASTMKLFVLDAAYDMFA +RGTLHPQDRIVVKNQSLVGSRSFAYAQSGQPVAVAELLRVMIQYSSNLATNLLIERV-GV +PYIRAVIRTQHIKGVRFGRMIEDFDAN-ARGIHNQMTAKGLGLFMQKLDHGEIVGPEQSR +AMIDILRGQTF-NDMIPPGLPSGTPVAHKTGWVD-GVRNDAGIVFLPDGQHYILVMLSRS +LP-DEAAGVRVLNTVSRQVYDHf +>[subseq from] Serine hydrolase n=1 Tax=Muribaculaceae bacterium TaxID=2498093 RepID=A0A4S4H7Z8_9BACT +---LRQDISGFVEKQHGKIGVAVI-TDRKDTL-TVNNTPDFPLMSMFKLHQSIAICRNFG +ENGIGLDSVLNIKQCEMNKWSPMLKNNMDKDIPVSGLLEYILVHSDNNASNLLFNRVVSV +AETDSIVASLPDRGFRLMYNEYEMLQDKSLSYKNVSSPLAYALMIDKLFTDSLMPHSMQA +FVKQAMYNCETGMGRIAAPLAPGVAFAHRTGSGYVNAVNDGGYVTLPSGQSYSIAVFVKD +FAGTQDEAESVIAKISELVYN-- +>[subseq from] Beta-lactamase class A n=2 Tax=Actinomadura madurae TaxID=1993 RepID=A0A1I5CVG9_9ACTN +-------IEAEFRAAGVTGFLHVVDMDTGREV-AVGADEPVVLASVFKVPLLVAFHRQAA +RGLLDPAEQVTLRPDDRTAPTGVSALLDEVRMSLRDLTCLMITVSDNAAADVIMDRV-GR +EAVNATAAELGLDGTVIEVDGRELHEALDPLRTSRSTPRDMTRLLSMVWRDEAAPAGGCA +AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGARYAVAVFTRS +LLAVLPEADAVIGTAARIAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. TSRI0281 TaxID=1718998 RepID=A0A1Q4YVM3_9ACTN +------------AEAGVTGWLHAVDIDSGAQI-DAGADRPVVTASVHKLCLLVALHQQAE +AGRLVLTEQTECPRDGRTAPTGLAAMLDAARVSLRDAAYLMVAVSDNTAADLLLERV-GL +DAVNDTTRRLGLTRTHATQTFREFLAAVDPARTNRSTPRDMTRLLGAIWRDEACTPEHGA +AIRRLLGLQVW-PHRLASGFPDDVLVAGKTGSAPT-VRNEVGVVEYPDGGRYAVAVFTRA +ASATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02414 TaxID=1703922 RepID=A0A1Q5CTI7_9ACTN +---TAARLGAAFADAGVTGWLHAVDIDSGAQV-EAGADQPVCTASVHKVCVLVTLHELAA +AGEIDLTERVECPPAGRTPGPTGLAAMLDPVLSLRDAALLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGALWRDETCPAEYGA +AMRRVMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT +ANATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=5 Tax=Streptomyces TaxID=1883 RepID=A0A1H2BZB7_9ACTN +----AARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVTLHELAA +AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL +DAVNRTAARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLGAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. C1-24 TaxID=2495913 RepID=A0A5A7S6T4_9NOCA +--QVEKRIRDVFADAGCTGWLHARRLDSHSAQlSVDGDQLVVTASVYKLPLMVALCRCFD +AGEIDPLEQVRVVPAQCTPPTGISIFRDPVTLSWRDLATSMIVVSDNSAADIVLGRV-GL +TRVDETIAALGLARTRVVGGTAAVHAAYDPSYASATTPREMNDLLGAIWSGAMLSATQTA +YVKDVLGKQLW-QHRIRSGFPGGVEVAGKTGTIGI-IRNEVAVVTFPGESPVAVAVFTRA +ARADLPAVDAAIGEVARIAVS-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces kasugaensis TaxID=1946 RepID=UPI000B9E3D1E +----LTRIREAFDGAGVTGRLHALDIDSGAEV-GASADHPVVTASVHKLCLLVALHQQAA +AGRVDLTEQIECPPAGRTSGPTGLAAMLDPVMSLRDAAYLMMAVSDNTAADLLLERV-GL +DAVNHTTARLGLAHTHAVYTFGETFGALDPARTNHSTPRDMTRLLAAIWRDEACAPAHAA +AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA +TNATFPPADAVIGTTARIAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Parafilimonas terrae TaxID=1465490 RepID=A0A1I5Z9H0_9BACT +--KLQQQITELIKDFHGDIGIYVHDLKHHKTV-SINADTVFPTASIVKISILAGIMNKIQ +HGELDYHQRLLYTDSLYYSGDDILSNFKDSSIELSKVMMLMLTISDNCASLWLQGLAGGG +LTINALLDSLGYKNTRVNSRTPGRETYRSQYGWGQTTPREIATIMNDIVDKKIISTEASE +KMLRLLGRQYW-DEEALSQIPAGIFTADKNGAVDE-SRNEVLYVNCK--NPYIFSIFTKN +NKNADNEAWVLTRKLSALLWKHf +>[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus acidophilus (strain ATCC 700253 / DSM 10332 / NAL) TaxID=679936 RepID=G8TU74_SULAD +-qTLDNELMAVQREFSGRYAVYAEHLGTGETV-SFGDQTAWETASVMKLPILTEALRQCQ +EGVHALTEPVEYRRDDGVPGSGVLQYLTPGVLPFKDVLTLMVIVSDNVATNMVLRTI-GI +EAVNQTCHDMGLMQTRVMRRIDFS----SPDPLGLSSPFDLVQLLKSLYFNTVLDSRHAG +IAVEILRHQQY-QTLLTRYLPYDVTVASKSGSLT-GIRNDAGLVISPWGD-YAVAIMSEA +SKDRDTEAFQVLPRVSRAIFDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus zhangzhouensis TaxID=1073327 RepID=A0A1M7ZHC4_9BACT +--GLEKEIQSLVEGFHGDVGIYIQELGNDRKI-EINADTVFSTASIVKIPIMLGIFDKIE +KDELSFHQALMYRDSIKYGGSGLMQFFQDSTTDLRTLIALMLSYSDNTTSLWNQALAGGG +TQINELMEKLGYTNTRVNSRTPGREKIWEKYGWGQTSPKEMADILVRIYQKELITPAASE +QMYRLLSNTYY-NDYALSQIPPGVNVASKQGMVN-ASRSEVFLVNGPESD-FVVAIFTDH +NEDTDNEAWELTRKITLLVWNYf +>[subseq from] Beta-lactamase class A n=1 Tax=Phormidesmis priestleyi Ana TaxID=1666911 RepID=A0A0N8KNG7_9CYAN +---LKAALQDLPNRYNLTPKAFYIDVDTGDYV-SLDGGDTIAAASTIKLPILLAFFEEVD +AGRITTNQMLELLPHQVAEGSGGMQFAPGTQFTALEVATQMIVDSDNTATNMMIDLLGGM +AALNERFKGYGLAKTQISASLPDLPGD------NTTSAKDLVNTM-LLISGDRLTLRSRD +RILNILNRTYN-KDLLADGMEKEALTYNKTGDIES-VLGDVALVDLANGKRYVVAVLVER +PSND-GRAVDLIHTISERIYK-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia brevicatena TaxID=37327 RepID=UPI0002EBF803 +---VEDRIRAVFADAGCTGWLHARRCDSDDEV-SVAGYDRVVTASTYKLVLLLAFCHAVD +TGRIDPREPVTVIPAECTPPTGISALRDPVTMSRRDLATSMMTVSDNAAADLLLDEV-GL +GAVEALLTRVGLAGTRIVGGTADVHRAYDPAFTSSSTPEEMTRLLLAVWTGAVVSVEQTG +FVRAVMRSQVW-PHRIASAFPRGVTVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA +ARADLPVVDAAIAESARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinomadura meyerae TaxID=240840 RepID=A0A239JA14_9ACTN +------RIEAEFRSAGVTGWLHVADIDTGRDV-AVGAAEPVVLASVFKLPLLVAFHRQAA +TGVLDPAEQVTLRPQDRTAPTGVSALLDEVRMSLRDLTCLMITVSDNAAADTVLDRVGGR +DAVNEAAAALGLRDTVVEVTGRELHEALDPARTSRSTPRDMTRLVSLIWRDEAAPAADCA +AMRRLLGLQVW-PHRLSSGFPDDVQVSGKTGTLLT-VRNEVGAVEYPDGARYAVAIFTRS +LLAVLPRADAVIGTTARLAIE-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_40CM_4_68_4 TaxID=1805077 RepID=A0A1Q7HUG9_9CHLR +-nALRDSLDSAVTEFNGTAAVVVSGVDTNFRY-AKNDDAVFPSASLYKLEVMVEAYRQVA +AGRISLDDTVTVNWDDMSV-DP-SDTLPGTTLSVRDAIERMITISDNGPAHALTRLL-DP +HNVNATTLSVGMKDTRINAALPADE---QLAEDNTTSARDMERLFSGLATGKIVSPDASA +EMLAVLFRQQL-NDRLPSGLPADAAIAHKTGDLIQ-VAHDAGLLLTPFG-PRVVVVLTSD +FS-DYDEVSRLMARVAAAAYT-- +>[subseq from] Beta-lactamase class A n=2 Tax=Pedobacter nutrimenti TaxID=1241337 RepID=A0A318UKM8_9SPHI +---LSGMLTELTRGFQGQVGIYVKNLKTGKSA-GFNADSIFPTASMVKVPITSGVFNKIV +HKELDYRSTLIYKDSLLYAGEDILGSFKNNEIALSKVLMLMITTSDNTASLWCQSLAGGG +TAINKLMEENGLQFTRVNSRTPGREANRKQYGWGQTTPREMATLLSLIRQGKLISPAASE +RIYRNLIRIYF-DQVALSEIPPYIQVASKSGAVDE-ARSEVALVNAPHGD-YVFCITTKN +QKNSSNEGWALIRKLSSMLWNYf +>[subseq from] Beta-lactamase n=1 Tax=Clostridia bacterium 62_21 TaxID=1635276 RepID=A0A101FPT1_9FIRM +-nALLSRLVDVLQNEKGTYGVYLLDLKSGHWL-GINHEEPFHAASTFKLPANLYLYEQIA +AGRISPQTVLTYRKEHYEAGTGLLQYRPVGSFTIATLARYSIVYSDNVANNILISYV-GK +QNVKNYMRNLGGKL--------------VSDTQNVTCPRDMAAYTLHLLKFASEHPEQGN +ALLDLLENTVF-NDRISKPLP--VKVAHKIGNWPTGTYNDVGYVKHPEN-PYVIAVFSKY +TP-GKERACQVIQTISRLVYNY- +>[subseq from] serine hydrolase n=1 Tax=Eggerthellaceae bacterium zg-886 TaxID=2682776 RepID=UPI00140E7616 +--NLAATVSGIISSYGANASVTLSDLDDYATF-AVDGSEPHVSASMIKLAIMAEVFDQVN +SGYLALEDSYTVQESDIVGGTGTLQGGPGTQLSLSDLVRHMIAESDNVATNMLIDLV-GM +DAVNEEAVKLGLNATSLQRYMMDTDAQ-AAGIENHMSSDDAAVILILIANGEFYTPELSQ +LATDFLSQQTD-AGGIAPSLSSGETFAHKTGTLTN-VRHDAGIVQ--GEAPYVLSVFVEG +TDEG--SALSLMGEVT------- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. VT-16-64 TaxID=1917019 RepID=A0A1V2SA09_9BACI +--SYKRHIETLAQEASGKTAVYICTPDG--EI-KINEAERMQAASVIKVPIVMAGLHASD +QGMLDLNKKVVVQ--DKVAGTGVLNYLSGNMLSILNMMTLALIVSDNTASNLLIHEI-GR +ENINAFCQKAGASQTVLGRYFMDH-EAMERGIDNYTSAGDMIRFFRLIGHNKLLSNESRK +VIYQMLENQQFREKLAQAMFHDKVSIANKTGELN-GIQHDVGMFTFENRQ-VYAAILSSN +WN-NNYQGREFISQIGKLTIEY- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Shapirobacteria bacterium CG09_land_8_20_14_0_10_38_17 TaxID=1974884 RepID=A0A2H0WQS9_9BACT +--SIEKDLWQLVAPAKGVYGICIVDLGKGNTS-GINKDEIFPAASLIKLPLIYAFYQQVE +LGKIDPNEQYSLKEGDKIEGTGSVYQQPAGTYTLRQLAALMGKQSDNTAQNILAKIL-GE +EKIQAAIVDLGMEKTSYLDWE--------------TSPKDIAIFWQKLATGQTLTTAHRQ +EILDFLTNTIF-EEQIPAGLPEGIKVAHKIGMDE-GVLHDAGIVFAD--QPFILVLMSKG +VDL--DEAKQILPKITERVWE-- +>[subseq from] Uncharacterized protein n=1 Tax=Rickettsiales bacterium TaxID=2026788 RepID=A0A2D6ZZS8_9RICK +---LSSEIKRIVAYQPQSVFFAAYHLESGKFL-NINGDLTFPMASLVKTFIACTYLDLVD +EKKIDPDKKISIARENLRPYSIFSKLFIRPNISLNNLLEAMMIYSENSATDILFHEIGGI +KAINGFLKKNKLKGITVSRSILELISIFFSNTKDSSTALAYQKFLIEFQNGGLLSPSSTN +YLKKIMKKNIHGKYRLKGFLPKN-SFMHKTGSLSM-LTNDAGIFELPKNGHLILVSVLER +KPYRMPDSNEFI----------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces tendae TaxID=1932 RepID=A0A6B3QLM9_STRTE +--ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVTLHELAA +AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL +DAVNRTAARLGLTRTRAVYGFGEMLRALDPARTNRSTPRDMTRLLGAVWRDEACPAEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus alkalitolerans TaxID=1550385 RepID=UPI0013D0D432 +---LSTGLTEEIKKCPGQMSIMLEV--DNHTF-EWESDRKITSASLIKLPILLEGFKQIE +LGKWNLSEAIQILESQKVEGAGVIQALSTAELSVHDLLTLMIIVSDNTATNILIDLF-DM +EQINAFIKDSGCVSTELNRKMMDFK-AIEKGINNWTTSREMMLMLQEIDNGSRFSSKSRD +YMKGILHNQQL-LDKLPLFIDKGW-IGNKTGELP-GIEHDCAIMKVGGRT-AYISVLCDD +LP-SKGKGKIAIANIGELVWKY- +>[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Oceanobacillus picturae TaxID=171693 RepID=A0A0U9HBJ2_9BACI +-------------------QYSVLLTSGEGSL-AINEQQLRPAASLAKIPILIEACQQIE +SGRLHPDKLVYIEEEQFVGGSGIISHLTNSHYSYMNLIELMVIVSDNTAANVLLESL-GM +GAVNQTIEQLGAKNTVINRKFMDTKAQ-QEGLENYTTALDMVTLLKAISEEEYISSKSRK +FMRSILAKQQL-TNKLANFLHPSVTIFHKTGELC-GIEHDAAILECKEER-AYITVLSDH +LP-SNAEGQHTIAQIGKHAIDY- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gastranaerophilus sp. (ex Termes propinquus) TaxID=2029980 RepID=A0A2L2X499_9BACT +-------LAHAKQHSHLSPSIYIWDYSSGRSV-EIDSEAPVSAASIIKIPILFEFFRQIE +DKNANLSTKVKFEELYRTSGSGDMQYLKSGGYTFDYLANKMITESDNTATNIILDYIGGA +QGMNRALRGWGLENSYMSNWLPDLRGT------NRMSAKDVASVLYNLDNPSFLSAVHKE +QIKEYMGNVKN-RSLLRAGLPDEAILLHKTGDIGT-MLGDAGVVLRSDGRKYIIVVMAKR +PFND-YSAREFVKETSALVYK-- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. TMED90 TaxID=1986600 RepID=A0A1Z9W7G5_9SYNE +--ALSERWKQLAAGEDLTVSAFMLVLDDGRYA-QLAPDTALPAASAIKTPILLVTLEELD +AGKLSWNEPLTLTKPVVGGGAGWMAKPLGTRFPTHEVATEMIRVSDNTATNLLIERLGGK +DALNARFNTLGLSATAVNNWLPDLKGT------NTTSARDLARSIALVDTGEALSIRSRD +LFREVMGTSVT-NTLLPKGLLRGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG +PFND-PRSTELIRKLAAAM---- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. Marseille-P2415 TaxID=1805471 RepID=UPI0009884A85 +--------IRKLERLPGKISFLYENLETGDVI-SYHEKEPVMAASVIKLFVMAAIFERME +QGLLDPEKIFSIKREDCVPCGALTYLHDGILVTAMDLVTLMIIFSDNTAANVLIDYL-GM +EQINGTIKALGFEQTLLQRKMYDVLRS-RRGIQNYITAFETGRLFKMMYDGTLISRQASD +KMISILKNQQL-CSKIPQALPEEPEIAHKTGEDT-GITHDAGIIYGK--KPFLVC-FCGN +ET-DTPAFERVMAEIS------- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium TaxID=2044944 RepID=A0A4Q3B450_9SPHI +-qKLQLKLNELVKGFKGDVGIYVKNLKTGKTA-SINADTIFPTASMIKVPITCGVFNKIE +KGELDYHAQLMYCDSLLYAGEDILGSFKDSEISLSKVLMLMITTSDNTASLWAQLLAGTG +TAINEVMANNGLKDTRVNSRTPGRKDNQKKYGWGQTTPKEMATLLALIRDGKMINPAASE +RIYRNLIRIYW-DSEALSQIPPTVQVASKSGAVD-AARSEVCLVNAPHGD-YVFCITTKN +QQNYSNEGWTMIRKLSNLLWNHy +>[subseq from] serine hydrolase n=1 Tax=Nocardia abscessus TaxID=120957 RepID=UPI00030227BC +--------QEIFRTAGVEGWVYARCVGCGAEA-GSGADEPVVLASVVKVPLVLEFARQVA +AGQLDPTDRVRARAADRLGGVGTAGCADDVEFSLRDAAYLALTVSDNTAADLLFDRV-GL +DNVRSLLRELGLTATRVVGPPRAVVRALDPGRTTASTPREMARLLTLIALDQAGAPEACR +WVRDLMRQQVN-WYRLAAAFPPEVQVWAKTGTLP-GVRNEIGVVEYPDRTRYAVAVFTRA +ATQRLPEVDRAIGAAA------- +>[subseq from] serine hydrolase n=1 Tax=Candidatus Gastranaerophilus sp. (ex Termes propinquus) TaxID=2029980 RepID=UPI000CE9CF20 +-------LAHAKQHSHLSPSIYIWDYSSGRSV-EIDSEAPVSAASIIKIPILFEFFRQIE +DKNANLSTKVKFEELYRTSGSGDMQYLKSGGYTFDYLANKMITESDNTATNIILDYIGGA +QGMNRALRGWGLENSYMSNWLPDLRGT------NRMSAKDVASVLYNLDNPSFLSAVHKE +QIKEYMGNVKN-RSLLRAGLPDEAILLHKTGDIGT-MLGDAGVVLRSDGRKYIIVVMAKR +PFND-YSAREFVKETSALVYK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. SLBN-109 TaxID=1913101 RepID=A0A542PDW2_9ACTN +--ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVTLHELAA +AGDLDLTEQVECPPAGRTPPTGLAAMRDPVRLSLRDAAFLMMSVSDNTAADLLLRRV-GL +DTVNRTSARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLAALWRDEACPAEYGA +AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A2E7DIE4_9GAMM +-dKMQSDLEAIIDDYEGVAGVHVIDLSSGYRW-AYRDKLVFPQASAIKIPILLELFRRAE +SDPELLGRRVEMTDEVRTAGSGVLQVLTHGGLSLEDYAIYMILHSDNTATNVLIEQL-GM +EAVNKLSASLGASKTLLQRKMIRPEQSLS-GNENLSTPQEAALIMEKIESCDLMSQQGCD +RVRSILELYKD--GAIRNPIPREVPIAFKPGGIT-GVSTVWGIVDVPDR-PYVLTVMSNY +GG----NGGEVIEKISAVTYNFf +>[subseq from] Serine hydrolase n=1 Tax=Kyrpidia spormannii TaxID=2055160 RepID=A0A2K8N9W0_9BACL +-tALKQAINGYITSQPGTYGVVVVDLDSGAKL-DIDGNRVFFAASTFKLPMNLYLYTLIA +QGKVDPNTKLIYEASDYEDGTGIASTPVGTEYTIRELSQASIVASDNVATNILLDDL-GV +DNVKAFMRQLGGKEV--------------VDGDNVTTPDDMALYAVKLFEFVKKNPTVAA +PLIDDLEHTDF-NDRIPAKLPKGVPVAHKIGNWTD-QWHDVGIVFLSGR-PYVISLFSRD +IDQD--TAAQVLSTVSRMVYDY- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. ScaeMP-e48 TaxID=1100823 RepID=UPI000823CF6C +----ERTIRSLFDDAGVRGWLHVAELDRPSAHvVLDPDEQVPMGSVYKVPLMTAFCRLAD +AGRIDPSHRLTLGAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRAV-GP +EAVDRVCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPADIARLLRAIWTDEAASPASCS +FMRAAMGTQAW-AHRLASGFPDDVTVYGKTGTFGS-MRHEAGVVELADGSAYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Chloracidobacterium sp. CP2_5A TaxID=2012633 RepID=A0A257B752_9BACT +--EMARRLRRRLASFKGKVFCFAKNLDTGETF-GLAPDAKVRTASTIKVPIMVEVFAQVA +EGKLAWDDKLAIVRRHEYEGGVLFELTPGTQITVRDAMRLMIVVSDNIATNILLDRI-TT +DAVNARLAQMGFESIRSLRKIAGGGEENQKYGIGVATSREMVKLLETLERGAAVSPEASR +EMLAVMKRQQY-RDGIGRRLR-GVEVANKPGALDH-LRSDIGIVYTKRG-RIAMAITVED +LPCSEAEGHLLIADI-------- +>[subseq from] serine hydrolase n=1 Tax=Clostridiaceae bacterium TaxID=1898204 RepID=UPI001362DB94 +-eELRQAIERQRAVCSGESAVIVKNLTTGERI-ACNERDVFPAASLIKLPVLFTLYKRKK +-EGFFLGERIRMEQGHKVGGFGILKDEPGLTLSWKDLAVLMIIVSDNTAANWLIDFL-GM +DAVNREIKALGLSETELNRKMMDAAA-KEMGLENRTSAADMERMFEAV-----LKDADSE +EMMDILKRQQC-NNKLPVFFGEHGGFAHKTGDLP-GTEHDAGILFTGNQA-FFTAVLTRD +LR-DNRDGIRLNQEIGRLVYHY- +>[subseq from] serine hydrolase n=1 Tax=Spirosoma lacussanchae TaxID=1884249 RepID=UPI001108E124 +-sTLEKRLHTALTGFRGDVGIYVRNLRTGQTV-SINADTLFPTASTIKVPIQCGLFDKIH +QGALTYGQVLTYKDSLRYGDDIVGSLKDGAKIPLSEVVMLMETVSDNTASLWCQALAGGG +AAINAWLDKNGFPQTRVNSRTPGRKGDWSQYGWGQTTPRELANLLVYIREGKAVSPDASD +EMYRNLGRQYW-DNDGLSQLPPEIKTASKNGAVDR-SRSEVVLVHAPHGD-YVYCVMTKN +QKERSNEGFTLLRNVSAILWQHf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI0006E32A2D +----RDRIRAAFAEAGVTGWLHATDIDSGAQL-EVDADHPVVTASVHKLCLLVALHQRAE +AGHLDLAEQTECRPEGRTPGPTGLAAMLDTALSLRDAAYLMMSVSDNAAADLLLARV-GL +DTVNESTRKLGLARTHAAHTFGEFLAALDPARTNRSTPRDMTRLLRAVWRDEACSPRHGA +AIRRLLGLQVW-PHRLASGFPDEVHVAGKTGSAPT-LRNEVGVVEYPDHGRYAVAVFTRA +ASPSLPAADAVIGTAARIAVE-- +>[subseq from] Beta-lactamase class A n=2 Tax=Chitinophaga sp. OK723 TaxID=2135605 RepID=A0A4R7CEP9_9BACT +-kRLTAILAPLLTAFNGQAGIYVHHLKTDRIV-AINADTTFPTASMIKTAIQVGIFNKLA +KGELQYHQNLVYRDSLLYKGEDILGSFRDSEIALDKVMMLMLTMSDNTASLWLQSLAGGG +GVINQWLQEHGFEHLRVNSRTKGREANRQEYGWGQTSPREMARLLEMIYKGEVISAAASE +RMYRNLTRNYW-DQEGLTQVPTNVRTASKNGAVDE-SRSEVIMVNAPHGD-YVYCIITKN +NKNHDNEAWQLLRKVGFAIWQYy +>[subseq from] Beta-lactamase family protein n=1 Tax=Synechococcus sp. (strain RCC307) TaxID=316278 RepID=A5GRX5_SYNR3 +-qALSRRLAEIAAQKDLKVGAFVLVLDDGTFA-QLHPDRPLSAASSIKTPILLVAFEALD +QAKLSLNEALSLNKTVVGGGAGWMGSQPGSQFSIFEVATEMIRVSDNTATNLLIQRLGGK +DSLNARFIELGLEGTVINNWLPDLKGT------NTTTPRDQARAIALVETGQTLSARSRD +LFRQTLGTSRT-DTLIPRGWLRGVRVYNKTGDIGI-AYVDSALVELPDGRRVVASYMVEG +PFND-PRSTNMIRALAAA----- +>[subseq from] serine hydrolase n=1 Tax=Slackia sp. ZJ350 TaxID=2709799 RepID=UPI0013EA657A +--NLAATVSGIISSYGANASVTYTDLDGYATF-AVDGSEPHVSASMIKLAIMAEVFDQVN +SGYLALEDSYTVQDSDIVGGTGTLQGGPGTQLSLSDLVRHMIAESDNVATNMLIDLV-GM +DAVNEEAAKLGLNATSLQRYMMDTDAQ-AAGIENHMSSDDAAVILLLIANGEFYTPELSQ +LATDFLSQQTD-AGGIAASLSSGETFAHKTGTLTN-VKHDAGIVQ--GEAPYVLSVFVEG +VDEG--SALSLMGEV-------- +>[subseq from] serine hydrolase n=1 Tax=Slackia sp. ZJ119 TaxID=2709798 RepID=UPI0013EB7105 +--NLAATVSGIISSYGANASVTYTDLDGYATF-AVDGSEPHVSASMIKLAIMAEVFDQVN +SGYLALEDSYTVQDSDIVGGTGTLQGGPGTQLSLSDLVRHMIAESDNVATNMLIDLV-GM +DAVNEEAAKLGLNATSLQRYMMDTDAQ-AAGIENHMSSDDAAVILILIANGEFYTPELSQ +LATDFLSQQTD-AGGIAASLSSGETFAHKTGTLTN-VKHDAGIVQ--GEAPYVLSVFVEG +VDEG--SALSLMGEV-------- +>[subseq from] Uncharacterized protein n=1 Tax=Flammeovirgaceae bacterium 311 TaxID=1257021 RepID=A0A0D3LJD2_9BACT +---LQQKLERLVKGFRGDVGIYVHHLERGNTA-AIAADSIFPTASMIKVPITIGLFRKIE +TGELDINQPLIYRDSLFYEGEDLLGAFKDSAVKLSKVAMLMITTSDNTASLWAQQLAGTG +TAINGWLQENGYAHTRVNSRTEGRKEAWSTYGWGQTTPREMARLLVQIRQGKVINPAASD +RIYRNLCNIYW-DDVALTQLPPTVQAASKQGSVNQ-TRAEVVLVNAPSGD-YVFCIITKN +QQETDNEGWELIRHVSALLWQHf +>[subseq from] Uncharacterized protein n=2 Tax=Caproiciproducens galactitolivorans TaxID=642589 RepID=A0A4Z0XZ10_9FIRM +--------ENEINNSNANVSLLVHDFTRSQTLlSFHAEQKVVAASTIKTLILLAALEKVQ +KSELELSQMVTVPALEILPDTRVFDRDVR-EYRLEELLTWMIITSDNTATNVLIDLL-GM +DAVNAYCRKLKLESTVLERKMHDWG-AIEQGRNNYTSAINQLTVFAALHRRTILTPKLCD +RALGILKRQRDYSLAFRYIADESLTAAHKTGGLDR-LNHDSGLFYLDGN-VYYFGCFVSE +SMKENPVSKKLIGRLSREVYEYf +>[subseq from] Beta-lactamase n=1 Tax=Deinococcus swuensis TaxID=1182571 RepID=A0A0A7KFV8_9DEIO +------------QGYGGEVGLRICDLVGQELF-ALNAARVFPAASTIKVPLLVLALEWAQ +TGRLRLEDRVTLQAADRVPGAGVLHELGPGLLSWRDVLTLMIVVSDNTATNLLIDLL-GV +ETVNTWLEARGWSQTRLVGGLERRNATQRRGERNCTSALEQTDLLGRLVRGELLDEVHTA +LALDILERQQL-RDVIGPGLPRAYRLASKSGELD-GVHHDVGILYTP--RPLVVALLSEG +GAD-------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Handelsmanbacteria sp. (strain RIFCSPLOWO2_12_FULL_64_10) TaxID=1817868 RepID=A0A1F6CBM3_HANXR +--QVREPLQNILAQCSGRVGVAAQDLRTGREI-AWRADESFPTASMIKMAVLVELERQAL +AGEQSWEASLRLTPEAKVGGSSLLRRMSDGLLPVYDLAYLMMTVSDNTATNLLIDLV-GL +DRVNRTMADHGLSEIRLNNKIDFSRLWRDPNDFGVGAPRAFCRLMADILEGRLLTPDACL +HMLKLMDGVGA-GERLARYLPYNLHFAGKTGSLT-GVRAHTAALWSEEAVRLAFSVMVAD +STDRDMDGLLTIARIGKLVYDTf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID5910 TaxID=2690312 RepID=UPI00136DE7E6 +--TVTGRLRAAFDEAGVTGWLHAVDIDSGAQV-DAGADQAVCTASVHKLCVLVALHEQAA +AGLLDLTERVECPPAGRTPPTGVAAMLDPVTLSLRDAAFLMMSVSDNAAADLLLDRV-GL +DAVNRTTARLGLTRTRAVSSFGQMLASLDPARANHSTPRDMTRLLAAVWRDEACPPEYGA +AMRRVLGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. KBS0724 TaxID=1179674 RepID=A0A554QYC8_9NOCA +--SAQQEITAVLAEAKTDAFVHARDIDSGEEF-GYGADDGVILASVFKIPVVLEYARAVA +AGTLDPTEHATVTAEFRSGGIGVGGCADDVTASWRDLALLMMSFSDNAATDFIYHRL-GL +DNIVSTLRGLGLEKTNLVRDCRGLFKVMDPARTNSSTPREITALLAAIWRDEAGPASACD +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVSYPDGKRYAVGVFTKS +HEKRAPKIDASIGTVGRIAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium TaxID=2044944 RepID=A0A3S0E468_9SPHI +-kKLQQKIELLVSGFKGTVGVYIKDIKTGKEA-MYNADTIFPTASIVKVPILLGIMDKIN +KRELEYEQELIYKDSLLYEGEDILGSFKSNEILLKKVMMLMLTTSDNTASLWLQSLAGKG +TRINEILDSLGFISTRVNSRTPGRENNRTQYGWGQSTPKEMALLFEKIYKKEIINEAACD +RMMRCLGRNYWDLNEAISQIPPTIEVFSKNGCVD-ATRNEVLLVNAPHH-PFIMSIFTKN +NEDQDNEAWALARKLAAMLWKYf +>[subseq from] Serine hydrolase n=2 Tax=unclassified Synechococcus TaxID=2626047 RepID=A0A368CIP0_9SYNE +-kALSAKLAQLAAQKDLQVGAFALVLDDGSYG-QFKPDLVLPAASAIKTPILLVALEALD +AGKLQLDELLSLNKTVVGGGSGWMGGQPGSQFTVLEVATEMIRVSDNTATNLLIQRLGGK +TALNARFQELGLEGTVINNWLPDLEGT------NTTTARDQARSIALVETAQVLTPRSRD +LFRQTLGTSRT-DTLIPRGWLQGVRTYNKTGDIGI-AYVDSALIELPDGRRAVASYMVRG +PFN-SPRSTNMIRALSGATAAAf +>[subseq from] Serine hydrolase n=1 Tax=Blastocatellia bacterium TaxID=2052146 RepID=A0A317HY46_9BACT +--EMDAQVKKAIAAFKGTVSLYAKNLETGETY-AVNADERVRTASTIKIAVMIEAFARVE +EGKAKWTDEVVLTKEKKVSGSGILFELSDGLLTLRDALNLMMMLSDNTATNLVLDVL-TT +DAVNARMESLGFKQIKILRKVGSGGDSIAGDPENFATPHEWVLVMEKLERGEIVSKAASK +EMIELMKREQA-RYAIGRSLS-DLPMASKYGALDR-LRSAVGIIYSKKGR-IAMAISCDD +M---------------------- +>[subseq from] serine hydrolase n=1 Tax=Cyclobacterium xiamenense TaxID=1297121 RepID=UPI0012B88EF1 +---FTQKLEEEMANFGGETGLYVEHLASGEIF-AIRADSLFPTASVIKVPIMVGIFKQIH +DKKLELDTALLYRDSIRYGGSGLMQYFKDSTTDLATLLSLMIGYSDNTASLWCQELAGGG +QEINKLLDSLGLEHTRVNSRTAGRQEAWEKYGWGQTSPREMVSLLRMIRHEELFSPELSQ +KMYRLMSNVIY-DNYALSAIPPYIQTASKQGMVSS-SRSELVMVNGPSGD-YVFYIATKN +NRDEDNEAYRLQRKLSGMLWNYf +>[subseq from] Uncharacterized protein n=1 Tax=Virgibacillus profundi TaxID=2024555 RepID=A0A2A2IIL5_9BACI +--QLENAIRDLIQNNKHNFSISIHT-QE-GNI-SINAAKQRKAASLAKISILLEAYRQIE +NNKLSLETPIYINKSAMVGGSGVLNYLTNSHHSLQNLLELMIIVSDNTASNLLLEHV-GM +ENINKLTEKTGCKQTIIKRKFMDLQAQ-MVGFENYTSSQDIATLLKIISKNNVLSDKSRH +QMLEILSNQQF-KDKLAAYLTDKIEIYHKSGELQ-GIEHDAAIFKYHEN-TIEVAVLSEG +WI-NNGEGKKYIAAIGKLLIT-- +>[subseq from] Serine hydrolase n=2 Tax=root TaxID=1 RepID=A0A5N9B355_9CHLR +--KLVKSINTQVENFNGVAGVSIKDLTTGWYY-GINDELIFPTASSIKIPILLKLIESSE +ASKLNLLKNIEITEEMKSRGSGVIHKMNGTILTVENLAILMINLSDNTATNLCIDIA-GQ +DEVNKMLEDYEFVSMRLNRKMQDYT-AIKEGRENLSSVKEMNLILEMLDSSRAIKPEVAK +KVLNILSLNKS--TPISQPLPENIIVAGKTGGMP-GVRCETAIIYLANKK-YILTVMTSY +AGNGSSSSNQNI----------- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E8CW33_9PLAN +-----AELDATAKKFAGRIGFFVRDIASGADY-GWNSDERFPPASVIKLPVMIELYRQAA +DGRLDLDKKLRLPTDISTHGTGVLKKNDRPVLPLPEYADLMMIHSDNMATDFIIRTV-ST +EATNRFLDAQGFRNTRVSLELGRWHYYSDSLKNNVCAPRETVLLLERLYKGRLTSEKHKE +AILEPMRYSTH-KDTIARHVKDGIQVANKYGGSQR-IAADAGIVEIPDR-PIAIACFALA +KDPADRSGREVLAEMCRLAI--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces celluloflavus TaxID=58344 RepID=UPI00069AEEC1 +----LTRIREAFDGAGVTGRLHALDIDSGAEV-GASADHPVVTASVHKLCLLVALHQQAA +AGRVDLTEQIECPPAGRTPGPTGLAAMLDPVMSLRDAAYLMMAVSDNTAADLLLERV-GL +DAVNHTTARLGLAHTHAVYTFGETFGALDPVRTNHSTPRDMTRLLAAIWRDEACAPAHAA +AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA +TNATFPPADAVIGTTARIAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Lunatimonas lonarensis TaxID=1232681 RepID=R7ZMJ4_9BACT +--TLIETLKRELAGFKGTAGLYALNLQTGEEI-AINADTLFPTASIIKVPILVGVFDKIE +QGELTYNQPLMYRDSLKYGGSGLMQFFQDSTTDLSVLVSLMITYSDNTTSLWCQALAGGG +VAINALMENLGLVHTRVNSRTPGREANREQFGWGQTTPREMAQLLVKIRKGEVVSPKASE +RMYRLMTNIYY-DENALSAIPPYIQTASKQGMVN-ASRSELVMVNAPGGD-YVFYIATKD +NEEEDNESYVLKRTVSRLLWEAw +>[subseq from] serine hydrolase n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=UPI0012B7A429 +------------SHMSGKTGFYYKDLATGETA-GFQEKAQFRAASVYKLPLFAGILLLAH +RGEADLFAKVRIAEDEKIPGCGAVQHLTGEPLDVLSLCKLMITISDNTATNALARYF-GI +ERMKPVFRELGLSGTQMNRCLYDLEKE-EQGIQNWIVPEELGGLLEGIHRRTLISPEVSA +YLEEILLQQQI-NHKIPGIMGENVPVAHKTGEED-GTTHDVGIVCAK--RPFVVCFTSNE +TD--VPVFEDFIR---------- +>[subseq from] Beta-lactamase n=1 Tax=Lacrimispora sphenoides TaxID=29370 RepID=A0A381JQP3_9FIRM +-------IIKKLERIPGKISFLYEDLKTGEGF-AYHEQEPMMAASVIKLFVMTAAFEKSK +KGTFQMDKLFPVKREDCVPCGALTYLHDGILVTGLDLVTLMIIFSDNTATNILIDIL-GI +EEINDTIRGLGFRHTLLQRKMYDIERS-SRGIQNYITAYETGRLLKMMYEGTLIDRRSSE +AMISILKNQQL-CSKIPQALGESPEIAHKTGEDM-GITHDVGIVYGK--EPFL-VCFCGN +ET-DTPAFERVMAEVSLELYK-- +>[subseq from] Peptidoglycan-binding domain 1 protein n=2 Tax=Candidatus Gottesmanbacteria TaxID=1752720 RepID=A0A0G0ZAD4_9BACT +-eEIEAEISRLTSDSSGTYSVYLEDLNSGRNF-GINEQMVVTAASVNKIPILAALYHKAG +KNEIDLDRIIVPQAKDVQDTGSIRYDAPGTAYSLKTLARLMMEKSDNTAAYILASLVVGL +DDIQNLIESWGLTQTDMK--------------INKTSAKDIAIITIKMYRSEITGKALTA +EMIDFMDDSDF-EDRIPKGIDGNTKVYHKTGDEVR-TVHDAGIVDLPGK-PYFLAVFTTD +IV-DEEATKTKIAQISRIVYEN- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. Ag82_G6-1 TaxID=1938853 RepID=A0A286CK85_9ACTN +----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA +AGLLDLTEQVECSPQARTTPTGLAAMLDGARLSLRDLAYLMMSVSDNAAADQLLERV-GL +DAVNRTTARLGLARTLAVHTFGELLSALDPARTNRSTPRDMTRLLAAVWRDEACTPEHGA +AMRRILGLQVW-PHRLASGFPDDVHIAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT +ARTSLPAADAVIGTAARLAVD-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A351FH05_9BACT +-dSLQSRVAARLDRLDAISSIYAKHIPTGREI-AVRADHPMNTLSVIKIPVMVKAFQDNA +SGRLDFGERYTVGPNDMRRGSGLIQTFEPGLPTLRSLVTQMIITSDNTATDMVIKAV-GL +DRVNALLQNEGFSQTRLKATTGDLFRAFEGDSTGKTTAREMGNLLEQILNAELADEEASA +EMIAMLTRQFY-TSRLPQRVRQGVSVAHKTGDWPPIAGNDVGILFYDGG-PSIVSVFTNQ +NTGDFFELEATLGLIAEDIVEAw +>[subseq from] serine hydrolase n=1 Tax=Clostridiaceae bacterium TaxID=1898204 RepID=UPI00130DA5E0 +--------VEKLEDLTGSISFLYENMITGDKV-SYRENEPMMAASVIKLFVMAAAFEKIE +KGVLDGSEMIGIRLEDCVPCGALTYLHEGIMVTVMDLITLMIIFSDNTAANVLIDLL-GM +DWINRFLKDQGFEKTLLQRKMYDLKLS-SQGIQNYITAGETGRLLKMMYEGILVSGQASQ +KMIGILKNQQL-CSKIPQALPEEPEIAHKTGEDR-GITHDVGIIYGK--EPFL-VCFCGN +KT-DTPAFERVMAQVSLELYE-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. 12(A) TaxID=1163671 RepID=UPI0004634574 +-----AEMVKRLEQFPGKVSFYFENLVTGETM-RYHEQAPMMAASVIKLFVMASVFEGLE +RELFQPDQMFEIKRAHCVPCGALTYLHDGIQVTLMDLVTLMIIFSDNTATNVLVDFI-GM +ESINGTISRLGFEKTVLQRKMFDLEKS-RQGIQNYITAGETGQLLNMIYHGNLVSRCASE +RMVSIMKNQQL-SGKIPFYLPDRPEIAHKTGEDT-GISHDVGIIYGK--VP-FIVCYCGN +ET-DTPCFERFMAEISLELYQ-- +>[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces yanglinensis TaxID=310779 RepID=A0A1H6C6Z9_9ACTN +--TVEQAIRDMFADAGVRGWLHASDLDRDARV-TIDPEHPAPMGSLYKVPLMAAFCRLVD +AGALDPRARVTLEPSDHVPPTGISLLRDPVSVSLRDLVVLMMTISDNTAGDAVLREV-GA +EAVEEVCRDLGMSRTHIEGGTARAWSVYDPLSKASGTPADLGRLLRAIWTDRAASAANCA +FMREIMGRQAW-RHRLASGFPDDVTVSGKTGTFG-AMRHEAGVVALPGGGTYVVAVFTRA +ARVDLPRADAVIGAAARAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Actinocorallia populi TaxID=2079200 RepID=UPI000D08CC71 +--------------------LHAVDLDSGREI-GVRPDESVVLASVFKVPLLVAFFRRAA +AGELDPVEQVALPPGARVAGGTGTSVLLDEIMSLRDLACMMITVSDNTAADTVLERV-GL +DHVNRTLTDLGLVRTRVTGSAGDLHAALDPAVSSRGTPRELTRLLAAIWRDEAAPAPECA +QMRRMLGLQIW-PHRLASGFPDDVLVSGKTGTLLT-LRNEIGVVEYPDGGRYALAVFTRA +RSATHPRADAAIGTAARLAVQ-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CS113 TaxID=1982761 RepID=A0A209BTV5_9ACTN +--ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVTLHELAA +AGDLDLTEQVECLPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL +EAVNRTSARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLAALWRDEACPAEYGA +AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Salegentibacter salarius TaxID=435906 RepID=A0A2N0TXF7_9FLAO +--ELQQKLEALIDDFKGDVGIYVKNLETDKVV-AINADTIFPTASIVKVPILVKIFDNID +KGDLNYNDTLVYSTDRIYGGSGLMQFYQDSTTDLRTLVALMISYSDNVTSLWNQELAGGG +EAINELMAELGLEYTRVNSRTDGREKDWEKYGWGQTTPREMASILVEIRNRDLISPAASD +EMYRLLGNSFY-QDYALSQIPPYVQAAAKQGMVNK-SRSELFMVNAPSGD-YVCYLATKN +NEEDGNEAWELQRKISALLWNYf +>[subseq from] serine hydrolase n=1 Tax=Arsenicicoccus sp. oral taxon 190 TaxID=1658671 RepID=UPI00067C1A18 +-qSLQRDLKDIVRHAPGRLSIQVVG-PTGVVA-GWDADREVPAASLVKVLVLVAALREVD +GGRLSLDQTLQLPE-ERVGGSGALSLLPSVTLAVVELLRLMVTLSDNDAANLLLHLL-GH +DRVTRTGREIGLQHTQVARNLRDRAAA-ESGRDNTTTAADQAGLLAALRAGQVLGGASTR +LALALLAEQQH-AYGVTALLPDGVVRGSKPGDLP-GVRHDVALVETGGS-WATVAVTATG +MY-DERH---------------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2C5A8_STRVZ +-------LRDAFAEAGVTGRLHAVDIDSGAEV-DFGADQPVVTASVHKLCLLVTLHQRAA +AGELDLTEQVECPADLRTPPTGISAMLDPVRMSLRDIAFLMMAVSDNTAADLLLARV-GL +DAVNATTAALGLDRTHAAHTFGELLAALDPARSNRSTPRDMTRLLAAVWRDEACAPEHGP +ALRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA +AGAILPTADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Actinosynnema sp. ALI-1.44 TaxID=1933779 RepID=A0A1V2PK15_9PSEU +---IGAEIEAVFADAGARGFVHAKQIGDGPEV-GVGADDQVVLASVFKIPVAVAFAREVA +AGRLDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDLIFHRV-GQ +AAVDQVLADLGLARTRLTGCCEDLFAVLDPDRTTSSTPREITALLDAIWTDRAGDTAACE +RVRKIMAQQIW-PHRMSSGFPAGVAIAAKTGTLP-AVRNEAGVVTDVDGRQYAVAVFTRA +DSDRLPAVDAAIGKAARLAVDH- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces variegatus TaxID=284040 RepID=A0A0M2GW32_9ACTN +----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA +AGILDLTEQVECPPQSRTTPTGLAAMLDGARLSLRDLAYLMMSVSDNAAADLLLERV-GL +DAVNRSTARLGLGHTLAVHTFGELLAALDPARSNRSTPRDMTRLLAAVWRDEACTPEHGA +AIRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT +ARTSLPAADAVIGTAARLAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinomadura echinospora TaxID=1992 RepID=A0A1H6A0H6_9ACTN +---IEERIERAFRDAGVVGCLAAIDLDDGRLV-GVRADRPVVIASVLKVPLLVALHRQAA +AGIVDLSEQVVLRPGERTTPTGVAVLQDEVRMSLRDLAAMMITVSDNAAADTLFARV-GV +ETVNAVLAELGLHRTHIPGCCRELFDALDPARTARSTPEEIAQLFAAIWRDEAAPAAECA +RMRRLFGLQVW-PHRLASGFPDDVQVSGKTGTLPT-IRNEAGVVEYPDGGRYAVAVFTRS +LSSVLPRADAVIGTTARMAVEH- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004CD69F1 +----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA +AGILDLTEQVECPPQSRTTPTGLAAMLDGARLSLRDLAYLMMSVSDNAAADLLLERV-GL +DAVNRSTARLGLGHTLAVHTFGELLAALDPARSNRSTPRDMTRLLAAVWRDEACTPEHGA +AIRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT +ARTSLPAADAVIGTAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. H23 TaxID=2541723 RepID=UPI00106E0AF6 +--ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQAVCTASVHKACVLVTLHELAA +AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEIGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium IBVUCB2 TaxID=1985174 RepID=A0A1Y2RFN5_9BACT +-kKLQSKLEEAIKGFNGDIGIYVKNLRTGKTA-FINADTIFPTASIVKVPILVGIMDKIN +SGELKYDSSLVYKDSLLYAGSDILGSFKNNEVLLKKVMMLMLTTSDNTASLWLQSLAGTG +TRINEILANHGFKDTRVNSRTPGREENRTQYGWGQTTPTEMGMLFEKIYHSEIISATACE +RMMRSLGRNYWDVDEAISMIPPTIEVFSKNGCVN-ASRSEVLLVNAPNN-PYIFCIFTKN +NKTHENEAWTMARKISKMLWDYf +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus metallilatus TaxID=1211322 RepID=A0A5R8UM16_9DEIO +-------------GYVGEVGVLITDLAGRELY-ALHPARLFPAASTIKVPLLLLALGEAQ +AGRLDLRERVTVRAEDRVPGAGVLHELGPGLPTWEDLLTLMIVVSDNTATNLVIERL-GM +ERVNAWLGERGMIGTRLIGPLERQNEAQRRGERNRTSARDQVALLGALVRGEVLDQAHTA +LALSILGRQQL-RDLLGRHVPRGYRVASKSGELL-GIHHDVGVLFTP--RPLVAAVLSEG +G---------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Aminicella lysinilytica TaxID=433323 RepID=A0A4R6Q2G8_9FIRM +-----EDIVKRLKEQKGRVGFYCKNLVTGQVM-EYKSDEQYLAASVIKLPVFMSISKWDS +EGKASMSDKVQVRNEDKEPICGALTLFTDEPVDVRTLCNLMISISDNTATNLLIKKY-GI +LELSNEFLKIGLKDTELNRILFDPDKS-HAGLENCIVPSEMAMLLEKVYRGTFVSKKVSK +DIEDTLLLQQI-NHKIGGIINDEVPIAHKTGEDD-GVTNDVGIVYA--REPFVICFA--G +TDTDVPEFEDLIRHVSYEVFKEy +>[subseq from] hypothetical protein n=1 Tax=Rubrobacter radiotolerans TaxID=42256 RepID=UPI001356587B +------------------------------------------------------------ +-------------------------------GTVRSLSGAMISDSDNVATNLLVDRL-GF +ERINAAAQDLGLKETRLERHMLDFDAQ-AAGRENYTSARDTAALLAEIWHGRTLSPESRE +LALSTLELQTR-RAKIPAALPAGTRVANKTGELP-GVEHDAAIVLVPDRS-FVLVTLTSG +DPDS---GVEAIHAA-------- +>[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Microgenomates group bacterium GW2011_GWA2_37_6 TaxID=1618497 RepID=A0A0G0K3D1_9BACT +-eQLKENVEKIIKNKKGFYSVYYKDLKTGELF-GIDENQIETGASVNKLPIITALYLLDK +KGKLSLDDKVTIQKEDVQDTGSIRYQKMPQVYSLRNLAKLALQQSDNTAAHVLSLRI-GE +ENVQKLVDSWGLKQTDMV--------------NNKTTVYDMSLLFEKIYRGEIANPANTK +ELLEFMTETEF-EDRLTKSLPSGTKIYHKTGDGE-GFVHDLGIIENGDQ-VYFLGVMTSD +IGDQEEQTKNTIAEISKKIFE-- +>[subseq from] Serine hydrolase n=2 Tax=Terrabacteria group TaxID=1783272 RepID=A0A2E0EAX4_9ACTN +----SKRWSDLAALQDLKVSAFMLALDDGRYA-ELNPDTALPAASAIKTPILLVALEEID +AGRLSWNEPLTLNKAVVGGGAGWMAKPLGTRFPTYEVATEMIRVSDNTATNLLIERVGGR +EDLNARFSSLGLSATIVNNWLPDLKGT------NTTSARDLARAIALVDTGEALSIRSRD +LFREVMGTSVT-NRLLPGGLLKGYRVLNKTGDIGI-AYADAGLIQLPDGHRAVAAFLVKG +PFND-PRSTELIRNMASAM---- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis lexingtonensis TaxID=218822 RepID=UPI00117741D0 +--KVEQRIADAFLAAGARGFVHAREIGGAGEV-AVGADDPVVLASVFKIPVAVAYAREVV +AGRLDETERVRVGKRYRIGGIGTAGCADDVEMSWRDLALFMLTMSDNAATDVIYHRV-GQ +AAVDRVLADLGLGRTRLIGCCEDLFAVLDPERTTASTPREITTLLEAIWTDRAAEPAACE +RVRTIMAQQIW-PHRISSGFGSDVRIAAKTGTLP-AVRNEAGVLSFPDGRRFAVAVFTRA +DSERQPAVDAAIGKAARLAVDH- +>[subseq from] Uncharacterized protein n=2 Tax=Chloroflexi TaxID=200795 RepID=A0A3D1M3V0_9CHLR +-kQLEENLKNKLASFEGVAGLSVKSLTGDEAL-SIKGNEVFPTASTIKIHILTKLFSMEE +EGQINLSKRVRFTESMYGSGSGVIHFLENVPFTILDVAILMMLVSDNTATNFCIDLA-GM +EDINDLIQDMGLVETKLRRKMMDPA-AINRGNENISTPNELVAIMQKLHDG-IPSKSVSK +QVLRIMSKPKS--AYINKAIGSDITIANKPGGMDK-VRGDTGIVYLSNN-PYAVSIMSNF +SMVDSISQENFIIDVIRTIH--- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. CMAA 1363 TaxID=1843182 RepID=UPI000ADC01C6 +------------------NGLIRIHIEGKESI-RINSFIQQRAASTIKLLLAIEAFRQID +AGILALTSVIQRMEKNTVGGAGVLKALPQLTIKVEELLILMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLRKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A4P5V7M5_9CHLR +---------------NESVSIAAVHLLDGTGV-ALNADDVVPPASLFKLNILAETYRQIE +RNRVKLAQMITILPEDVAPGAGILQDRIGEAVSVGEALSLMIGISDNTAAFALLRTI-SS +RRLNECTRELGMLRTWFYVDER----------PDETSAGDVVTMLRAIIDGTIASPWGTD +QMLELMTQVQS-SAWIRSGLPPATRLAHKSGQLE-GIRNDAGIVFGPTG-PYALAVLTHD +LY-DPAVGEQIITAVTRVVHRYf +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus sp. AG1013 TaxID=2183996 RepID=A0A370FI28_9NOCA +------------------------DRRAGIEV-GASPDQPVVMASVYKLPLLVTFCRLVD +AGDLDPRRQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAVSDNAAADELLRRV-GV +DRVNETMGGLGLSSTRIVGGTADSLEGYDPVLSSATTPRDMTTLLSAVWTGAVLSADQTA +FVRVLMSSQVF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPRADAAIGLAARAAI--- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium saccharolyticum (strain ATCC 35040 / DSM 2544 / NRCC 2533 / WM1) TaxID=610130 RepID=D9R4S7_CLOSW +------EIIQKLEGLPGKISFLYENLKTGEGF-FYHEQEPMLAASVIKLFVMAAAFEKEK +KGTFRMNDIFAVKKEDWVPCGALTYLHDGILVTGMDLVTLMIIFSDNTATNVLIDIL-GM +KEINETIKELGFRQTLLQRKMYDTERA-ARGIQNYITGYETGRLLKMMYDGTLIDKESSD +TMISILKNQQL-CSKIPQALPESPEIAHKTGEDT-GITHDVGIVYGK--EPFL-VCFCGN +ET-DTPAFERIMAEISLELY--- +>[subseq from] serine hydrolase n=1 Tax=Intestinimonas butyriciproducens TaxID=1297617 RepID=UPI0006910316 +--ELNAYLAAEIAAFPGKTSLLVADLPTGAVRhAWQPEEPVPSASTIKVPILLAALEEVR +LGRLSLEQRVALPAAALLPDTEVFDR-GETDCSLWELLYWMTALSDNTATNVILDLL-GL +DAVSRYATRLGLRHTVCRRKMLDAAAA-AAGRDNRTSATDQCRLYRQLCLGRLLTPRLTE +TALDLLRRQRCMDAALR-YLPYPVDFAHKTGELD-GVTHDAGVFFQGSGG-YYLGIFTWE +GPDGDPEQKRYIGRLARAIYETy +>[subseq from] Beta lactamase n=1 Tax=Streptomyces fulvissimus DSM 40593 TaxID=1303692 RepID=N0CJ25_9ACTN +-----RTIRSLFDDAGVRGWLHVAELDRPSAHvVLDPDEQVPMGSVYKVPLMTAFCRLAD +AGRIDPSHRLTLGAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRAV-GP +EAVDRVCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPADIARLLRAIWTDEAASPASCS +FMRAAMGTQAW-AHRLASGFPDDVTVYGKTGTFGS-MRHEAGVVELADGSAYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. LL01 TaxID=1665556 RepID=A0A0J5H1F2_9BACI +--ELKKRVQGVVDSTAGHVSFVLED-DGGRRL-EMDADAQKKAASLIKIPILMAAFKQVE +SGELKLTDRFSIEVEGRVGGAGVIQFMDSGTFTLRDLLTLMIVVSDNIATNKVLDII-GM +DAVGEFCAEQGLSRTRLERKMMDFEA-VDAGLENRTSARDMLACLKLLHFEGAFSDVSRQ +KMLSILGGQQL-LDKLPFYMDDSVKVANKTGELP-GVEHDCGIVSFGAK-KLMVAVLVDN +LF-DNSIGKRTIQEIGRLVEE-- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A517I1D1_BREBE +--ELEKRLSAIIGQAEGTWGVVVEEKGKGTCF-EHVPNELFIAESVIKVPIMAAVFAASE +QGHFRLDDPLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK +AQIDQTMIDLGMRKSCYSRKLMIYPLD--ITENNKITAGEVASMLGQMATGSYLSERACK +EMIAIMKKQQV-RNGLPSQLPNEWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD +VTA--QSALNTLGLLGRAVYD-- +>[subseq from] serine hydrolase n=1 Tax=Kribbella catacumbae TaxID=460086 RepID=UPI0003631B78 +----SARIRATFDDAGARGWLHAVSLDHPDQTvALDPDVVVPIASVYKLPLLAAFCHLID +TQELNPREQVTLAPEDRIPGATGLSILQDPVMSLRDLAVSMMTVSDNAAADALLNRV-GV +DRLAQLLQSFGLEHTRVRRGAAGNLSMYDAAGMSASSARDMTTLLASLWSGRLLSEEQTA +FAQRLMQQQVF-SQRLASGFPDGVRVAGKTGTFG-ALRHEVGVVVMPGGDAYAVAVFAHA +ARGDLPRVDAAIGEAARLAVDQ- +>[subseq from] Serine hydrolase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A3E4U320_9CLOT +---IERRIEAELMSYDGTMGIYADDF-HGNVI-AIGADEPFETASTIKTYILACLFDQVE +KGKASLEDMVEFKEEHAVDGSGVMCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL +DTINACIRGLGCRDTVLHNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPEADA +KMLEIFKKQHY-NSMITKDFPAVVNVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNKK +FSDAAHPATVFGARVSRMLFDQf +>[subseq from] Serine hydrolase n=1 Tax=Planomicrobium sp. Y74 TaxID=2478977 RepID=A0A3L7J7I5_9BACL +------QVKNALQHSSGKVSLAIET--KNGRI-DINSHKQMKSASTIKMAVLLEAFRQID +RDLVKPYDIIRLQPEDFTEGSGVLFHLGSVKLSFEDLLTLMIIVSDNTASNLIMRII-GI +GSVNALLNRLGCKETVLGRQFMDIQAAL-VGIDNFTSAADLVTMLKAVDSGELLSEDSRR +RVLHMLKKQQL-LANLHGRIDDEVSVASKSGSLP-GVVNDAGIFEYRGNK-VFAAVLVND +SP-DNHSGQELIAEIGGYIYD-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia araoensis TaxID=228600 RepID=UPI0002EED88D +--------QEIFRTVGVEGWVHARCIDCGAEA-GIRADEPVVLASVVKVPLVLEFARQVA +AGQLDPADRVRARAADRLGGVGTAGCADDVEFSLRDAAYFALTVSDNTAADLLFDRV-GL +DNVRSLLRELGLTATRVVGPPRTVVQALDPRRTTASTPREMVRLLTLIARDQAGAPEACR +WVRDLMRQQVN-WYRLAAAFPPEVQVWAKTGTLP-GVRNEIGVVEYPDGKRCAVAIFTRA +TTQRLPEVDRAIGAAA------- +>[subseq from] serine hydrolase n=1 Tax=Bacilliculturomica massiliensis TaxID=1917867 RepID=UPI0010300971 +------------SHMSGKTGFYYKDLATGETA-GFQEKAQFRAASVYKLPLFAGILLLAH +RGEADLFAKVRIAEDEKIPGCGAVQHLTGEPLDVLSLCKLMITISDNTATNALARYF-GI +ERMKPVFRELGLSGTQMNRCLYDLEKE-EQGIQNWIVPEELGGLLEGIHRRTLISPEVSA +YLEEILLQQQI-NHKIPGIMGENVPVAHKTGEED-GTTHDVGIVCAN--RPFVVCFTSNE +TD--VPVFEDFIR---------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SID11233 TaxID=2706029 RepID=A0A6B3ERF7_9ACTN +------------------LHVAELHRPSARVV--IEPGEQLPLGSVYKVPLMAAFCRLAD +TGRIDPRHRVTLEPDDRVPPTGISVLHDPVTMSLRDLVTLMMTVSDNTAAAAVLRAV-GA +DAVDAVCRDLGMPDTRIHGGVVATFSVYDPAFKASGTPQDMARLLRAIWTDEAASAEGCA +FMREVMRRQPW-THRLASGFPDDVTVYGKTGTFGS-LRHEAGVVELADGSTYTAVVFTQA +ARADLPRADAVIGAAARAAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A4Q5QSE7_9BACT +-kRLQKKIQELVSGFEGEVGIFVKCLRTGKTA-NVNADTIFPTASMIKIPILIGVMDKIQ +KGELNYQQTIIYRDSLLYPGEDLLGSVKQDEIVLGKIIMLMLTLSDNTASLWLQSLAGTG +THINELMDNLGLKNTRVNSRTPGRATNQSLYGWGQTTPREMCLLMEKIYKGEVINKHASS +MMLRLLGRNFY-DEYALSAIPPYIFVASKNGAVNQ-SRSETLLVMSPNG-PYIFSIITKN +QKDQS------------------ +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. UW105 TaxID=337067 RepID=UPI000E0F5A1E +------RWRQLAAQQDLKVSAFMLVLDDGRYA-ELNPDTALPAASSIKTPILLTTLELLD +SGNLRWNEPLTLTKQVVGGGAGWMATPLGTRFPTHEVATEMIRISDNTATNLLIERAGGK +EVVNTRFNALGLSATEVNNWLPDLQGT------NTSSARDLARAIALVDTGKALSTRSRD +LFREVMGTSVT-NRLLPGGLLKGYRVYNKTGDIGI-AYADAGLIELPDGSRAVAAFMVQG +PFND-PRSTELIRSMAAAM---- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_40CM_4_68_4 TaxID=1805077 RepID=A0A1Q7HZD5_9CHLR +------------DALRGRSGVLICEADETVRF-ARDPDGVCPAASVIKVPLVMALYAEAA +RGALDLEHCVEVGE--RVAGTGVLTHLRDVHLTLRDHAMLTIIVSDNTAANRLIDSV-GL +GVVNAYLDQWGCPRSRLRRKMFDLDAR-ARGLENVMTPRESAHLLGMLVRGELVDRAISD +AVLEILSATTY-DGNARRYLPGGVSTANKTGQLEN-VRNDVAIVRVD--RPVILAAFTRE +LA-SEADGEAALGVVGW------ +>[subseq from] Beta-lactamase class A n=1 Tax=Halorubrum aquaticum TaxID=387340 RepID=A0A1I2Z3G0_9EURY +--DLARAVDSIADRFDGRLGVFLGVPRGPDEFhRRNADETFVAASTIKLPILYALYETYD +GRLDDLGEPRPIAAENRVGGSGVLHLFDDPTPSLEDLARAMIAISDNAATNQLIDEL-GA +ERIEAAATRLGMADTRLRRKLMATLEQPEGEPANATTPMDCARFFADLVHEATLSAPAYE +RLRVPLDEQKD-ASLFARYLPYGTPIAHKTGGLPT-AALDAGVLDPPDASPLAFAAFATE +AE-NGGDASDVVAAVGEAAFE-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. WAC 04229 TaxID=2203206 RepID=A0A429DNB9_9ACTN +--ATAARLGAAFAEAGVTGWLHAVDVDSGAQV-EAGADQAVCTASVHKVCVLVTLHEQAA +AGVLDLTEQVECPADGRTPGPTGLSAMLDPVLSLRDAAFWMMSVSDNTAADLLLHRV-GL +DAVNRTTERLGLTRTRAVYGFGEILGALDPARTNRSTPRDMTRLLTAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Chitinophaga sp. SYP-B3965 TaxID=2663120 RepID=UPI0012998D33 +-hKLEKALGELVKGFNGTAGVYVLNLKTGKYA-SLNGDTIFPTASIVKVPLLVGLFSKIE +KGELSFHQPMMYRDSIKYGGSGLMQFFKDSSTEVSVLAALMMAYSDNTTSLWNQQLAGGG +EQVNILMEQYGLKDTRVNSRTPGREEIRKIYGWGQTTPREMSFLLAKIHRGEVISKSASE +RMYRLMTKGYY-DEQALAEIPPYIQAAAKSGSVNE-SRSEVVLVNAPHGD-YVFYVGTKN +IKEADNEAVVMIRKISAYLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC401 TaxID=1848324 RepID=A0A5R8N176_9ACTN +---------TLFSTAGVSGWLHAADIDSGREV-GHGADVPLPTASMFKVPLLVEFCRQAD +AGLLDPSDRVTVPAAGRSSPTGISAMLDEVTLSLRDLAYLMIAVSDNGSADVLLARV-GR +EAVNTMLAAQGLHGTRVLQSCQEFNDALDPERTNRSTSREMSALFGLIWRDEAASAESCA +WMRAALNKQVW-PHRLASGFPDDVAVSGKTGTAPT-LRTESGVVEYPDGRRYAVAVFTRS +FSLNQPRADAVIGTAARMAVDH- +>[subseq from] Uncharacterized protein n=2 Tax=Gordonia effusa TaxID=263908 RepID=H0R326_9ACTN +-----DHVAHTFADAGCAGWVHARTLNSGVEY-GYRPDAPVVLASVYKLPLMISLCRMAD +RNDIDLAERVTVTPHDVAEATGLSVLHDPVTMSWRDLCVSMMTVSDNAAADVVLGRV-GL +HQLAADLADLSLSHTRIVSGMREVHAAYDAAYASAGTPRECTTLLDAVWRDVAASPDSCD +FIRRTMRKQVF-TTRIASGLAPHATVAGKTGTIGS-IRNEIAVVEFPGESSVAIAIFTKS +ARASLPTVDRAIGEVARAVV--- +>[subseq from] Serine hydrolase n=1 Tax=Rhodocytophaga sp. 172606-1 TaxID=2704465 RepID=A0A6C0GR65_9BACT +-rQLQEKLNSIVKDFKGEVGIYVRHLKSGKTA-AIQADSLFPTASMIKIPIMIGLFNKIK +TGELDYHAKLVYRDSLLYPGEDILGSFKDSAISLSKIVMLMITTSDNTASLWCQYLAGTG +TAINTWLETNGFQHTRVNSRTPGRQANQQLYGWGQTTPREMGELLVRIREGKAVSPDASE +RMHRNLTRIYW-DGEALSQIPPSVQAASKQGAVNQ-SRSEVVLVNAPSGD-YVFCVITKN +QQDETNEGYVLLRNVSRLLWQYf +>[subseq from] Beta-lactamase enzyme family n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5L4J8_9BACT +------------------------------------------------------------ +------------------------------------------------------------ +------LKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK +LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR +TEKNAKSDDAMIAEAAKRIFD-- +>[subseq from] Penicillin-binding protein n=1 Tax=Candidatus Beckwithbacteria bacterium GW2011_GWB1_47_15 TaxID=1618371 RepID=A0A0G1U4I8_9BACT +---------------NDRFGVWVEELSGSKSW-GLDETNQFTAASVIKLPILVAYYEAVD +EGRLDPETLYTLVEADRLEGTGSLQHQPAGTYSYREIAELTANQSDNMGAELLIKFLGGY +AAVQRTVNSWGLSETDLR--------------ENLTTPQEMGDLLTRLYRGELISEESRD +ELFANLTNTLV-EDRIPAGVPTGVKVVHKYGSEA-GVVNDCGIVYAD--TPYVICVLSQK +VN--AGEAEAVLPKISRVVWE-- +>[subseq from] Beta-lactamase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A174L172_9CLOT +---IEKRIEAELMSYDGTMGIYADDF-HGNVI-AIGADEPFETASTIKTYILACLFDQVE +KGKASLEDMVEFKEEHAVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL +DTINACIRGLGCRDTVLHNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPEADA +KMLEIFKKQHY-NSMITKDFPAVVNVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNKK +FSDAAHPATVFGARVSRMLFDQf +>[subseq from] Serine hydrolase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A3E3DPJ4_9CLOT +---IEKRIEAELMSYDGTMGIYADDF-HGNVI-AIGADEPFETASTIKTYILACLFDQVE +KGKASLEDMVEFKEEHAVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL +DTINACIRGLGCRDTVLHNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPEADA +KMLEIFKKQHY-NSMITKDFPAVVNVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNKK +FSDAAHPATVFGARVSRMLFDQf +>[subseq from] Beta-lactamase n=2 Tax=Synechococcus sp. WH 8016 TaxID=166318 RepID=G4FIT1_9SYNE +--ALSKRWEALAAKDDLQVSAFMLALDDGRYA-QLNPDTALPAASAIKTPILLVALEEID +AGRLSWNEPLTLSKTVVGGGAGWMAKPLGTRFPTHEVATEMIRVSDNTATNLLIERVGGQ +VDLNARFNSLGLSATKVNNWLPDLKGT------NTTSARDLARAIALVDTGEALSIRGRD +LFREVMGTSVT-NRLLPGGLLKGYRVLNKTGDIGI-AYADAGLIELPDGRRAVAAFVVKG +PFN-DPRSTELIRNMAAAM---- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. LL01 TaxID=1665556 RepID=UPI00069DD080 +--ELKKRVQGVVDSTAGHVSFVLED-DGGRRL-EMDADAQKKAASLIKIPILMAAFKQVE +SGELKLTDRFSIEVEGRVGGAGVIQFMDSGTFTLRDLLTLMIVVSDNIATNKVLDII-GM +DAVGEFCAEQGLSRTRLERKMMDFEA-VDAGLENRTSARDMLACLKLLHFEGAFSDVSRQ +KMLSILGGQQL-LDKLPFYMDDSVKVANKTGELP-GVEHDCGIVSFGAK-KLMVAVLVDN +LF-DNSIGKRTIQEIGRLVEE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Leucobacter komagatae TaxID=55969 RepID=A0A542XXE3_9MICO +-dTLTAQIAKVAEDAGVFAFAHARDIDTGREV-GFRSDDPTVTASVFKVPVLVEYVRQVA +AGELDPAQRIEVSPSEATMGPTGLSVFSDVAWSLRDIATSMITVSDNAATDIVTGLV-TV +DRVNSTMRELGLPGTQLTGDCSVIFDAATPEKTNRTTPREATSLLQQIWTDAAATPEACA +EARRILGMQVW-PHRLSAGFPDDVKISGKTGTIGM-VRNEIGVVEFPGGKRHAIAVFLRG +KTSRNPAADRAIGDIARLLSD-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=A0A0M0GS42_9BACI +--------------------------SHDESL-SWEENRRKSSASLIKLPIMMTAFEQIQ +TGSLNGDAMVVLRHEDHVEGAGVLNGHDGITLSIEDLLKLMITVSDNTATNRLIELI-GK +DSINRFCLTWNLKRTFLNRKMMDFRS-LEMGQDNWTSSMDVVSCLKGINEGPF-KEASKR +KMLTMLSRQQF-RDKLPALVGGDVKVFNKTGELP-GVEHDCAILESTSGKIAYVAVLIDG +LQAP-EDGRRAISRIGKLVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Sphingobacterium spiritivorum ATCC 33300 TaxID=525372 RepID=C2G3X8_9SPHI +-qKLEKKLKELTRDFHGDIGIYVRHLKTNKEV-MINADSIFPTASIIKVPILAGVFNKIG +KGELKYNDKFIYRQSRAYGGSGLMQFFKDSVTDLSTMAALMIGYSDNVTSIWCQELA-EG +TKINELMDELGLPNTRVNSRTAGREAIWKKYGWGHTTPREMATLLTLIREGKVISPDLSD +KMYRILGNVFY-NERSLSQIPSYIKTASKSGSLED-VRTEVVLVNAPSGD-YVFSVFTKN +NKEKSNEAEVLTRSISSLLWNYf +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BEE1B2C +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGILRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREISEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. IEGM 248 TaxID=2704615 RepID=A0A6B2KC48_9NOCA +-------------------------IDDGADI-AVGADDLVVLASVYKLPLLVALCRAFE +SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLAMSMMTVSDNAAADLVLGQV-GL +ESVERALSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE +FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA +ARTDLPGVDAAIGHAARIAVT-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces azureus TaxID=146537 RepID=A0A0K8PX70_STRAJ +----LARIHAAFADAGVTGRLHAVDIDSGAQL-DAGADQPVCTASVHKLCLLVSLHEQAA +AGILDLTEQVESPPEGRTTPTGLAAMLDGARLSLRDLAYLMMSVSDNAAADLLLARV-GL +EAVNRTTARLGLTRTYAVHTFGELLAALDPARTNHSTPRDMTRLLAAVWRDEACTPEHGA +AIRRVLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT +ARTSQPAADAVIGTAARLAVD-- +>[subseq from] Beta-lactamase class A n=2 Tax=Pedobacter sp. OK701 TaxID=2135718 RepID=A0A4R7ELC0_9SPHI +-pKLEKALQQLVKGFNGDVGIYVKNLKTGKSA-GINADSIFPTASMVKVAITAGVFNQIE +KGQLDYKSVLTYKDSLLYAGEDILGSFINGEIALSKVLLLMITTSDNTASLWAQSLAGTG +TAINDLMSQYGLTYTRVNSRTPGRQENQKKYGWGQTTPKEMATLLTLIRNGKLINEAASE +RIYRNLIRIYF-DQEALSQIPPYIQAASKSGAVDE-ARSEVVLVNAPHGD-YVFCITTKN +QKDTSNEGWILIRKLSQMLWHYy +>[subseq from] serine hydrolase n=1 Tax=Arthrobacter sp. GMC3 TaxID=2058894 RepID=UPI000CE4A2C8 +---VRDALSATLTAVGVRGYVHAIDIDSGLEI-GLDADTPVVAASVFKVPVLVELCRQYS +TGQRSPVERVKIAANERRTGSTGISAMLDDILSLRDLSFLMMSVSDNRATDIIVDLL-GY +DAINATLGSFGLSDTVVTRDCAGLFVAATAELTNHTTPREITSLLAAIWRDEVIGAEAST +EVRRILAQQAW-PHRLTAGFPSNIKVSGKTGTLFY-TRNEAGVVEFPDGGRYAVGVFLRE +PTEENPDADRVIGTVAKLAIDY- +>[subseq from] Beta-lactamase n=2 Tax=Cyanobium sp. PCC 7001 TaxID=180281 RepID=B5INI0_9CYAN +-----ESWARLAAAQGLQASGFLLVLDDGRYA-ELQADQALPAASSIKTPILLAGLEDVD +AGKIRWNEPLPLTKEVVGGGAGWMASRPGTRFPFFESATEMIRVSDNSATNLLIKRLGGK +EKLNARFQALGLPATVINNWLPDLEGT------NTTSARDLAKSIALVDTGETLSPRARD +LFREIMGTSRT-NTLIPLGLLQGVTVYNKTGDIGI-AYSDAALIHLPTGQRAVAAFMVKG +PFND-PRSAELIRSMAAET---- +>[subseq from] Beta-lactamase class A n=2 Tax=Rhizobiales bacterium GAS188 TaxID=1884351 RepID=A0A1H4S2V0_9RHIZ +---ASDIVAALRDRDGIDVGFSAIHLASGQCL-EINASSLFPTASVFKVPVMVEVFRQAR +AGIFAMSDRLTLATCHKTLTSGVLVTLDDGLPTIGDLVMLMTIVSDNTATKLLLDLV-GM +DKVNAAMAGYGLHDIHVAIDVHEMFLTFSRDRDNTASAADMARLMAMIAAGEVVDAEACG +SMVAIMKEQQY-SERVPRYLPFG-SVANKTGTMR-GVRNDSGIMRRGEGDDIAYAVFSFD +PTPLAAGNSRFLAE--------- +>[subseq from] Beta-lactamase n=1 Tax=Cupriavidus metallidurans TaxID=119219 RepID=A0A132HQX0_9BURK +--RVETALAPLLAGTQARVAISLR-LADGKVVlEREAERVQPSASIIKLPILFTLLEQVA +QGHLQLEQRFSLDGLERVGGTGILSQLPSVQLTLAELARLMIVLSDNLATNALIELL-GF +EGVNDWCDRAGLGQTRLQRRMMDAAAR-AAGLDNFTSASDAAASLCRLLRDGSLPAPLRD +FALGLLADQRE-RAHFGAALPADAMLANKTGQLP-GLRHDAGILTVGAY-SVVLAVLADG +FTDAGGDGAQWLAEAARIVA--- +>[subseq from] Uncharacterized protein n=1 Tax=Sphingobacterium spiritivorum ATCC 33861 TaxID=525373 RepID=D7VLX7_9SPHI +-qKLEKKLKELTRDFHGDIGIYVRHLRTNKEV-MINADSIFPTASIIKVPILAGVFNKIG +KGELKYNDKFVYRQSRVYGGSGLMQFFKDSITDLSTMAALMIGYSDNVTSIWCQELA-EG +TKINELMDELGLPNTRVNSRTAGREAIWKKYGWGHTTPREMATLLTLIRAGKVISPDLSD +KMYRILGNVFY-NERSLSQIPSYIKTASKSGSLED-VRTEVVLVNAPSGD-YVFSVFTKN +NKEKSNEAEVLTRSISSLLWNYf +>[subseq from] serine hydrolase n=1 Tax=Microtetraspora malaysiensis TaxID=161358 RepID=UPI000829A197 +--------KEVFDDADVEGFVHVREVDGSAEI-GLNPDEPVVLASVFKIPVVLEYARQAA +AGTLDRTERLTVTTADKDGGIGTSGCADDVSLTLRDLAHFMMTMSDNAATDVLLRRV-GL +DNLHATLRGLGLGRTRLIGGCAELLGVLDPERTTSGTPRETTSLLSKIWRDEAGPAEACA +EVRKIMGNQVW-PHRLSSGFGDEVKVSGKTGTLP-GVRNEAGVVEFPDGRRYAAAVYLRT +DSFRLPQADAAIGRAARMAIEH- +>[subseq from] Uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC 49176 TaxID=592010 RepID=W1Q2D6_ABIDE +-qAVQAAFASLYESKEIKHAYYFQEVTSQGAA-LVSQSGPIKSASIIKLFIMQVLLEEIK +AERLSWQEMITMMAEDQVGGTGNLQAEPGTSYSLEDLALEMLIHSDNTATNLIIERLGGL +SAVQAKIQSLGYQDTRLQRLMMDQV-AIAEGRENFTSAREVGQLLAKLYQHKLVGQAQDQ +IFLDFLAQQTD-RQGVVATLPQGVISYNKTGSNSQGLQHDAALVQLTNQSAYVLVVLQEG +PG--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. RSCCF101 TaxID=2511069 RepID=A0A5J6Q301_9SYNE +---------------DLKASGFLLILDDGRYA-QLAAGEPRSAASSIKTPILLAALEGID +AGSQRWDAPLTMDQEVIGGGAGWMAKPVGTRFPLHEAATEMIRVSDNTATNLVIRAAGGQ +EAVNRRFQDLGLTATVVNNWLPDLEGT------NTTSTRDLARTLALVDTGERLSPRARD +LFKEVMATSRT-NTLLPAGLLKGVSVYNKTGDIGI-AYADAGLIHLPDGRRAVAAFMVEG +PFND-PRSTDLIRAMAAAM---- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus qingshengii TaxID=334542 RepID=A0A4R5ZWG5_9NOCA +---LKEKIREELYGFDGRIGLAIEI-EDAGNF-YIDSEEVFRSASLIKIPIFLAGLGRHK +IGELDVEQLIPISKENRVGGSGILYALSDQLLTVKDLMTLMIIVSDNTATNILIDLL-GM +DKINAFIREIGFEHTKLNRKMMDFA-AIEKGIDNFTNSREMIHSLKLLNENNVIGITGPP +IAYHALRHQQF-RDKLPAMVNEKITVVNKTGELPS-VEHDCAIFEYQGRKG-YVAVLTDS +V-IDQNEAKQIIRNIGKHISDFf +>[subseq from] serine hydrolase n=1 Tax=Spirosoma sp. 209 TaxID=1955701 RepID=UPI00098D2F7A +-sTLEKRLQTALTGFRGDVGVYVRNLRTGQTV-AINADTLFPTASTIKIPIQCGLFDKIH +QGELTYGQVLTYKDSLRYGDDIVGSLKDGAKIPLSEVVMLMETVSDNTASLWCQALAGGG +ASINAWLDKNGFPQTRVNSRTPGRKGYWSQYGWGQTTPRELANLLVYIREGKAVSPDASD +EMYRNLGRQYW-DNDGLSQLPPEIKTAAKNGAVDR-SRSEVVLVHAPHGD-YVYCVMTKN +QKERSNEGFTLLRNVSAILWQYf +>[subseq from] Serine hydrolase n=1 Tax=Aminipila sp. JN-18 TaxID=2507160 RepID=A0A410PU96_9FIRM +--------------LKGHTGVYYKNLITGETL-LTKGEDQFLAASVIKIWVMAEAFYQIR +EGKIKREQKILLCDSDKIPEGGMPYLHSGIPFTVEDLYKLMIVISDNTATNMLIRLL-GI +DKINEFIASLHMSKTRLNRLLFDTSK----EKENTISLEEAGIFLEKIYRGEMISPEASR +EMCAILQNQQA-NFKIPFFLP-QIPIAHKTGEDN-GITNDVGIVYG--EVPFILCFAAND +A--DVPSANQACQEIARAAYRY- +>[subseq from] serine hydrolase n=1 Tax=Emticicia oligotrophica TaxID=312279 RepID=UPI00025F54D8 +--QLKAKLEETLKGFNGIAGVYVKNIKSNKFV-AINADTIFPTASMIKVPIMVGTFDKIK +KGELKYDQELTYKDSLDYDDGIVGSLKDGAKLPLNEVVMLMCTVSDNTGSLWLQALAGGG +KRINAIMDSLGLKNTRVNSRTPGREANRTEFGWGQTTPREMAELITMIRNGKVISADASD +RMYRNLGRQFWD-GEGLSQLPETVKYATKNGAVNR-SRSEVVYVHAPHGE-YVYCVITKK +QKDEENEGYELLRKVGALLWNYy +>[subseq from] serine hydrolase n=1 Tax=Streptosporangium roseum TaxID=2001 RepID=UPI0004CCB976 +--------------ADVEGFIHVRDVDGGAEI-GLGADEPVVLASVFKIPIVLEYARQAA +AGTLERTERLTVTAADKDGGIGTSGCADDVSLTLRDLAHFMMTMSDNAATDVLLRRV-GL +GNLHATLRGLGLERTRLIGGCAELLGVMDPERTTSGTPRETTTLLSKIWRDEAGPPEACA +EVRRIMGSQIW-PHRLSSGFGDEVKVSGKTGTLW-GIRNEAGVVEYPDGKRYAVAVFLRT +GSLRLPKADRVIGHAARVAIDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinopolymorpha cephalotaxi TaxID=504797 RepID=A0A1I2ZJR2_9ACTN +---VSTRIRAVLRDAHADAALHARSIFGAGEV-GLDADRRSAAASTYKVAVLLEVACQTA +EGRIGAADRIRVPSDRRTTPTGISILNDDVEMSVRDLAMLMIHVSDNTATDVLHELV-GH +EAVTARLRALGLTDTSFELDCHHLIASLRGERGNTTTPRDMTSLLSAVWRDEAGPPEACS +EVRRVMGHQFA-PHRLSTAYPNGPSVSGKTGTLFGGIRSEVGVVDFGGGEAYAVAVYLRG +HRRRDPDADRAIGRVARLAID-- +>[subseq from] Serine hydrolase n=2 Tax=Pseudonocardia sp. CNS-004 TaxID=1904967 RepID=A0A1Q9SG80_9PSEU +----------------------------AREV-GVDPDEPVVMASVYKLPLLIAFCRLAD +AGDLDPREQVTVEPSARTTPTGLSIMRDPVTMSWRDLACSMIAVSDNAAADVLLRRV-GV +DRVNDALSDLGLARTRVHGGTADVYRAYDAVLASATTAREMTTLLAAVWSDRAASPQQSR +FVRELLGAQAW-QHRLRSGFPVGVRVAGKTGTLA-AVRNEVGVVQFDGERPVAVAVFTRA +ARAELPKADAVIGQAARLAV--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL F-4707 TaxID=1519496 RepID=UPI0006ADE094 +--SVAARLDAAFADAGVTGWLHAVDVDSGAQV-GTRAEQPVCTASVHKLCLLVTLHELAA +AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNAAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-7442 TaxID=1519498 RepID=A0A0M8YU57_9ACTN +--SVAARLDAAFADAGVTGWLHAVDVDSGAQV-GTRAEQPVCTASVHKLCLLVTLHELAA +AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNAAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00137519A5 +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGILRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGYE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Beta-lactamase class A n=1 Tax=Siphonobacter aquaeclarae TaxID=563176 RepID=A0A1G9IBL9_9BACT +--RLQKEIDKLTTGFHGTIGVYVKDLKTGQTA-SVLADTVFPTASIVKVPILLGVMDKIE +KGQLGYHQNVVLTDSLRYPGSDEADMKTGEKIEISRLILLMLSTSDNTASLWLQGLAGGG +LRINAILDSLGYAQTRVNSRTPGRQHIRNRIGWGQTTPREMATLFEQIAAGKVFSRSASE +KMLRLLGRQYW-DQYALSQIPPDVFAADKHGCVNK-SRSEV--VYVAGDHPYVFAVFTQN +NQEPSNEAWTVTRKLSALLWKYy +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. ASBs410 TaxID=1304866 RepID=UPI000446AEB1 +--TLEKRIEAEIMSYDGKMGIYLDDF-HGNVI-AIHADEAFETASTIKTYILACLFDEVE +KGNKSLEDMIEYKEEHVVDGSGVLPDLEPGALRVKDAATLMIIVSDNIATNMMIDYL-GL +ERINQCIKALGCKDTVLHNPIHF-E---QYDRLGTSTPEDYASIFIRLAKGELISPGADE +KMLDILKKQHY-NSMITKDFPPFISVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE +FSDAAHPATVFGARVSRMILDQf +>[subseq from] Serine hydrolase n=1 Tax=Subdoligranulum sp. OF01-18 TaxID=2302962 RepID=A0A3A6KGA9_9FIRM +-qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERGAGRRAVSASTIKVFILLAALDEVR +RGRLTLDTPVAVTAEDILPDTGVFVDGP--GHPLEELLVWMIVLSDNTATNVLIGLL-GA +ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYDETVLTPELCA +LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD +AP-DIDGDEPLAGRVSKLVFDYy +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter pedocola TaxID=1792845 RepID=A0A1S9PBA2_9SPHI +-rKLTAQLQEAVKGFNGQVGIYVHNLKTGKTA-AINQDTLFPTASMIKVSILSGLMDKIE +KGELRYNQKLGYRDSLLYAGEDILGSFKDKDIQLSKVAMLMITMSDNTASLWLQKLVTG- +THINNWLDSNGFKSMRVNSRTPGREAFRSIYGWGVTTPYEMCKLFTMVRNGQVVSPAASE +RMARTLNRIYW-DNNALAQIPPYVQCLSKSGAVDE-SRSETVLVYAPHGD-YVFSVITKN +NKTPTNEASTLIRKVSALLWHYy +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. NAT40 TaxID=2024884 RepID=A0A2E0KBW8_9SYNE +------RWRQLAAQQDLKVSAFMLVLDDGRYA-ELNPDTALPAASSIKTPILLTTLELLD +SGSLRWNEPLTLTKQVVGGGAGWMATPLGTRFPTHEVATEMIRISDNTATNLLIERAGGK +EVVNTRFNALGLSATEVNNWLPDLQGT------NTSSARDLARAIALVDTGKALSTRSRD +LFREVMGTSVT-NRLLPGGLLKGYRVYNKTGDIGI-AYADAGLIELPDGSRAVAAFMVQG +PFND-PRSTELIRSMAAAM---- +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. 7K507 TaxID=2530365 RepID=A0A4R4U7P7_9ACTN +--DVTQRIEAEFRAAGVTGFLHVTDIDTGREV-AVRAGDPVVLASVFKVPLLVTFHRQAA +DGLLDPAEPVTLRPRDRTAPTGISGMQDEVRMSLRDLTFLMITVSDNAAADVLLDRV-GR +DAVNATAAALGLRDTIVECGGRELHEALDPLRTSRSTPRDMTRLLSMIWRDEAAPPDGCA +AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGGRYAVAVFTRS +PLAVLPRADAVIGTAARMAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis rifamycinica TaxID=287986 RepID=A0A066TUG6_9PSEU +--TVEAAIAAVFAEADARGFLHAREIGGGPEV-AVGADDPVVLASVFKIPVAVAYAREVA +AGRLDETARARVGSRYRIGGVGTAGCADDVEMSWRDLALFMLTMSDNAATDVIYHRI-GQ +AAVDRLLAGLGLGRTRLAGCCEDLFAVLDPERTTSSTPREITELLDAVWTDRAGEAAACE +QVRSMMARQIW-PHRLSSGFPAEVAVAAKTGTLP-AVRNEAGVVTYPDGRRFAVAVFTRA +NSERQPAIDAAIGKAGRLAVDH- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=Sphingobacterium spiritivorum TaxID=258 RepID=A0A380CPC3_9SPHI +-qKLEKKIKELTRDFHGDIGIYVRHLKTNKEV-MINADSIFPTASIIKVPILAGLFSKIG +KGELKYNDKFIYRQSRAYGGSGLMQFFKDSVTDLSTMAALMIGYSDNVTSIWCQELA-EG +AKINELMDELGLPNTRVNSRTAGREAIWKKYGWGHTTPREMATLLTLIREGKVISPDLSD +KMYRILGNVFY-NERSLSQIPSYIKTASKSGSLED-VRTEVVLVNAPSGD-YVFSVFTKN +NKEKSNEAEVLTRSISSLLWNYf +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. C105KSO15 TaxID=1776047 RepID=UPI000740888B +----------KLEQLPGKISFLYENLKTGDGF-AYHEQEPMMAASVIKLFIMAAAFEKSR +KGTFQMDELFAIKKEDCVPCGALTYLHDGILVTGMDLVTLMIIFSDNTATNVLIDIL-GM +EEINETIQGLGFERTVLQRKMYDTVRS-AQGIQNYITAYDTGRLLKIMYDGTLIDRQSSE +TMISILKNQQL-CSKIPFYLQDSPEIAHKTGEDT-GITHDVGIVYGK--EPFL-VCFCGN +ET-DTPAFERVMAEIS------- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteriia bacterium AA117 TaxID=2169412 RepID=A0A321L8U5_9BACT +---LKQSLQRTSQSVSADWGIYVKSLDTGEEI-AINADAVMDTMSVIKVPLLVDAYRLVD +AGKINPADRITMATADKRFGTGVLRTLNDGLLSVHDAFMLMVIQSDNTATDMVYSRVGGP +QHVNQTMHQMGFSTINAPGTAFDWFSFEGKHPFGVSSGREMGRLLEMITSNKAASQKSCE +DMMRILRMQQM-RTRIPRFLA-EVSAPHKTGDFPPYIANDVGLIETEKS-RVVVVFFCAH +HRGVYAELEDAIGRMSEQVWAYf +>[subseq from] Serine hydrolase n=2 Tax=unclassified Mucilaginibacter TaxID=2617802 RepID=A0A2J6H711_9SPHI +--KLTAQLQNLLKDFHGRAGVYVHNLKTGKTA-AINADTLFPTASMIKVSILNGVMDKIE +KGDLHYNQKLVYRDSLLYAGEDILGSFKNGDIQLSKVTMLMITMSDNTASLWLQKLV-GG +EYINNWLATNGFKVMRVNSRVAGREDMRKIYGWGVTTPYEMCRLFTLIHEGKAVSPAASE +RMYRTLNRIYW-DENALSQIPPYVQAISKQGAVD-ASRSETVLVNAPHGD-YVFSIITKN +NQTPQNEADILIKKVSALLWHYf +>[subseq from] serine hydrolase n=1 Tax=Algoriphagus vanfongensis TaxID=426371 RepID=UPI00047D8CB4 +--PLQEKIQPLLEQFHGKAGLYILNLKSGEEF-TYQADSIFSTASIVKIPIMLGIFDKIE +KGDLQFHQPLIYRDSIRYGGSGLMQHYQDSVTDLRTLLALMLSYSDNTTSLWNQSLAGGG +STINELLNTLGYQHTRVNSRTPGREKDWERFGWGQTTPREMASILTKIYRKELVSESASE +MMYRLLSNTFY-NDYAASQIPPGINVASKQGMVN-ASRSEVMLVNGHHGD-YVFALFTDE +NEDQQNEAWVLTRKLSSLVWNHf +>[subseq from] Beta-lactamase class A n=1 Tax=Prauserella muralis TaxID=588067 RepID=A0A2V4ANH7_9PSEU +---------DLFDAAGVHGWVHARCLGTGAET-GFGADEPVVLASVIKVPLVLEFARQVA +EGQLEPTDRVRVREVDRLGGTGTAGCADDVELSLRDVARFALTVSDNTAADLLFDRV-GV +DNVRSLLAELGLRATTVAGPPRDIVRALDPIRTTASTPMEMTRLLALIWSGEAAPPQACR +QVRALMAQQVS-WARLGAAFAPDATVAGKTGTLPC-VRNEIGVVDYPDGGRYAVAVFTRG +GGRPRPDIERAIGAAARHAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Siphonobacter curvatus TaxID=2094562 RepID=A0A2S7IIB4_9BACT +-tRLQKQLETLVKDFHGDLGIYVEDLKTHSVV-AIRADTIFPTASIVKVPILLGIMDKIQ +RGQLDYHQSVTLTDSLRYKEADLVNAKTGEKIEISRLLLLMLSTSDNTASLWLQGLAGGG +LRINQLLDSLGYEVTRVNSRTPGREAIRNQYGWGQTTPREMARLFTAISERKIISPSTSE +KMLRLLGRQYW-DQYALSQIPPDVFVADKHGCVNQ-SRSEVFYVAGP--HPYVCAIFTKN +NQEASNEAWTLTRKISVLLWKYy +>[subseq from] Beta-lactamase class A-like protein n=1 Tax=Kyrpidia tusciae (strain DSM 2912 / NBRC 15312 / T2) TaxID=562970 RepID=D5WWQ1_KYRT2 +-tALKQAISGYVTSQPGAYGVVVVDLDSGAKL-DIDGNRVFFAASTFKLPMNLYLYTLIA +QGKVDPNTKLIYEASDYEDGTGIASTPVGTEYTIRQLSQASIVASDNVATNILLDDL-GV +DNVKAFMRQLGGKQV--------------VDGDNVTTPDDMALYAVKLFEFAKKHPTVAA +PLIDDLEHTDF-NDRIPAKLPANVPVAHKIGNWTD-QWHDVGIVFLPGR-PYVISLFSRD +IDQD--TAAQVLSTVSRMVYDY- +>[subseq from] serine hydrolase n=1 Tax=Ruthenibacterium lactatiformans TaxID=1550024 RepID=UPI00067907D3 +-qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERGAGRRAVSASTIKVFILLAALDEVR +RGRLALDTPVSVTAEDILPDTGVFVDGP--GHPLEELLVWMIVLSDNTATNVLIGLL-GA +ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYDETVLTPELCA +LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD +AP-DIDGDEPLAGRVSKLVFDYy +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-146 TaxID=1463884 RepID=UPI0004C745EE +----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA +AGLLDLTEQVECSPQARTTPTGLAAMLDGARLSLRDLAYLMMSVSDNAAADQLLERV-GL +DAVNRTTARLGLARTLAVHTFGELLAALDPARTNRSTPRDMTRLLAAVWRDEACTPEHGA +AIRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT +ARTSLPAADAVIGTAARLAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Myxococcales bacterium TaxID=2026763 RepID=A0A2D8JEG7_9DELT +-dSLQSRIAARLDGLDAISSIYAKHIPTGREI-AVRADLPMNTLSVIKIPVMIQAFQDNA +SGRLDLGERYTVGPNDMRRGSGLIQTFEHGLPTLRSLVTQMIITSDNTATDMVIKAV-GL +DRVNALLQEEGFSQTRLKATTGDLFRTFEGDSTGRTTAREMGSLLEQILNAELADEEASA +EMISILTRQFY-TSRLPQRVRQGVSVAHKTGDWPPIAGNDVGILFYEGG-PSIVSVFTNQ +NTGDFFDLEATLGLIAEDIVEAw +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A3D2UDV6_9BACT +-dSLQSRIAARLDGLDAISSIYAKHIPTGREI-AVRADLPMNTLSVIKIPVMIQAFQDNA +SGRLDLGERYTVGPNDMRRGSGLIQTFEHGLPTLRSLVTQMIITSDNTATDMVIKAV-GL +DRVNALLQEEGFSQTRLKATTGDLFRTFEGDSTGRTTAREMGSLLEQILNAELADEEASA +EMISILTRQFY-TSRLPQRVRQGVSVAHKTGDWPPIAGNDVGILFYEGG-PSIVSVFTNQ +NTGDFFDLEATLGLIAEDIVEAw +>[subseq from] Beta-lactamase class A n=1 Tax=Thermostaphylospora chromogena TaxID=35622 RepID=A0A1H0ZY77_9ACTN +---IEERIREVFARVGVTARFHVIDVATGDEV-GLNADEQEVLASLFKVLPLLEFARQVA +AGQLDPTERVVVRSADRLGGWGTAGCADDVELSLRDLAYFMMSVSDNTAADLLVRRV-GL +DTVRMLVAELGLARTRIIGGSREMLAALDPEHTTSSTPREMTRLMGMIWRDEAGHPAACA +MVRELMTRQIF-WTRLGSGFPPSVRVASKTGTLP-GLHIEAGVAEYPDGGRYAIAVFARS +HNLQRIDIDLAMGRAARLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000C9B94C3 +------------------NGLIRIHIEGKESI-QINSFIQQRAPSTIKLLLAIEAFRQID +AGILALTSVIQRTEKHTVGGAGVLRALPRLTIKVEELLTLMIVVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRK +KIMRMLKIQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3B8VCT6_9BACT +-------FADIESKYEGNLHIHAIKLGSETSW-KYRENDLVATASTIKLPILMHAAMCVY +DGYLSWDTKITLKESDKVGGMGVLQHLNTPHLTLHDACYLMTAISDNTATNLVMDVV-GI +DNVNQFIRTFGLTDTKLFRKAFSPNTESKVFGLGQTSASDMLTLLSEIYRPNKLPLSVVN +DIRSMLSKQTD-QVSIPRVLPHGWSYEGKTGRVTE-VRGDVGYVKAPDGREWLLSMFCYG +LTTE------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Sediminibacterium goheungense TaxID=1086393 RepID=A0A4R6IWQ4_9BACT +-kKLQQKISRLIQGFNGDIGVYVHDLKKNKIA-VINADSIFPTASMVKVPILVGIMDKIG +KKELDYHQTLTYKDSLLYEGVDILGSFKNNEIELSKVIMLMLNTSDNTASLWLQSLAGTG +TRINQIMDSLGFKDTRVNSRTPGREANRTQYGWGQTTPREMAALFERIAGKQLLNDSASE +KMLKLLGRNYW-DEEGLSAIPAGIFVASKNGAVN-ASRSEVIYVNG-GGARYVFCICTKN +NKDQ------------------- +>[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. 16K309 TaxID=2530384 RepID=A0A4R4VKE0_9PSEU +---AEQRIRDVLADAGAQGWVHAVRLGGGHEL-GFGADELVVTASVYKLPLLVALARAFD +AGTLDPREAIRLDPGSCTPPTGVSTFQDPVRMSWRDLAASMIAVSDNAAADVILGAI-GL +DSLAAALDDLGLERTRVVGGTADAHAAYDPSYASATTPREMTRLMELIWADEVASPQQCA +FVRRLLGQQAW-MHRVRAGFPQGVQVSGKTGTIG-AVRNEVSVVEFDGEAPVAVAVFTLA +ARADLPRVDAAIAECARIAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga jiangningensis TaxID=1419482 RepID=A0A1M7L0S6_9BACT +-kKLQETLTHLLKDFHGQVGIYVHHLKNDKVV-EINADTIFPTASMIKTTIQVGIFDKIA +KGELQYRQPLIYRDSLLYAGVDILGSFKDSQIDLDKVVMLMLTMSDNTASLWLQSLAGGG +ATINSWLEQHGFKVLRVNSRTPGREEIRKVYGWGQTSPREMAQLMEMVYKGEVIDKASSE +RMYRNLTCNHW-DAQGLLQVPANIRTASKNGAVDD-ARSEVIMVNGPHGD-YVYCITTKN +IAKPENEAWRLMRKVGSAIWQHy +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF258FC +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGILRALLRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREISEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. ZY74 TaxID=2488634 RepID=A0A3N4PXG4_9BACT +-rKLQQALEEIVGRFNGRAGIYVQHLKTGAWA-AVNADTVFPTASIVKVPLLVGLFAKID +SGKLGYHQPMIYRDSAKYGGSGLMQFFKDSATEVSVLAALMMAYSDNTTSLWNQQLAGGG +AEINRLLEQYGFKDTRVNSRTAGREEIRKIYGWGQTTPREMTTLLIRIRRGEIISRAASE +RMYRLMSKGYY-DEQALTQIPPYVQAAAKTGSVNE-SRSEVVLVNAPHGD-YAFYIGTKN +IKEADNEAVEMIRTVSALLWKHf +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga niastensis TaxID=536980 RepID=A0A2P8HIN9_9BACT +--RLTAILTPMLASHHGQAGIYVHNLKTGSTV-AINADSTFPTASMIKTAIQVGIFNKLS +KGELQYHQNLVYRDSLLYEGEDILGSFKDSQIALDKVVMLMLTMSDNTASLWLQSLAGGG +VQINQWLQDNGFEHLRVNSRTKGREAERKQYGWGQTSPREMARLMEMVYKGEVISKTASE +RMYRNLTRNYW-DAEGVLRVPPNIRTASKTGAVDE-SRSEVIMVNAPHGD-YVYCMITKN +NQDQDNEAWQLLRRVGDVIWQYy +>[subseq from] serine hydrolase n=1 Tax=Ruthenibacterium lactatiformans TaxID=1550024 RepID=UPI000A50084D +-qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERGAGRRAVSASTIKVFILLAALDKVR +RGRLALDTPVAVTAEDILPDTGVFVDGP--GHPLEELLVWMIVLSDNTATNVLIGLL-GA +ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYAETVLTPELCA +LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD +AP-DIDGDEPLAGRVSKLVFDYy +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. KC06 TaxID=2530369 RepID=A0A4R4XVX1_9ACTN +-----ERIEKEFRSAGVTGFLHAVDIDTGREV-AVRADAPVVLASVFKVPLLVAFHRQAG +EGLIDPSEQVTLPAEGRTTPTGVSGMLDEARLSLRDLAFLMITVSDNAAADVVLERV-GR +DAVNAASAALGLRGTAVEVSGRELHEALDPARTSRSTPRDMTRLLSMIWRDEAAPPAGCA +AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +PLAVLPQADAVIGTAARLAVEH- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A348SI35_PSESP +-----ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE +QDDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI +DQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE +YLLSVMRRVETGGRRIKAGLPSGT------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A4P5T6U7_9BACT +-kKLEQKIKTLIQGFNGQIGVYVKNLKSDKIV-SYNGDTVFPTASIVKVPILIGIMDRIH +KKELDYHQKLVWYDTMNYDGEDIVAYKPQSEIELSKVMMLMMTISDNTGSLWLQSIAGTG +KRINHLLDSMGYHATRVNSRTPGREGDRSIFGWGQSTPNEMGRLMEDIVHGKIISKDKSD +QMLRIMGRQYW-DEEALSAIPPTVFVASKNGAVNA-SRSE--ILYVNGRRPYIFSVFTKN +NKGNENEAWQLTRKLSKLLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. Root239 TaxID=1736499 RepID=A0A0Q9ICX9_9BACI +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILTLTSVIQRMEKNTVGGAGVLRTLPRLTIKVEELLTLMIIVSDNTATNELISLV-GF +EKINECAKDLGLKKTVLNRYMMDEI-AVGKGIDNYTCASDVVKCLREIYEGNFLRKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=A0A133N6E3_CLOPF +------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE +EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM +NKINETIKELGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ +MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG +IPNS-VYGTVTLAKSGKMTWD-- +>[subseq from] Beta-lactamase n=1 Tax=Synechococcus sp. (strain WH8020) TaxID=32052 RepID=A0A0H4B6M0_SYNPY +--ALSKRWEALAAQDDLQVSAFMLALDDGRYA-QLNPDTALPAASAIKTPILLVAIEEID +AGRLSWNEPLTLSKTVVGGGAGWMAKPLGTRFPTYEVATEMIRVSDNTATNLLIERVGGQ +ADLNARFNSLGLSATKVNNWLPDLKGT------NTTSARDLARAIALVDTGEALSIRGRD +LFREVMGTSVT-NRLLPGGLLKGYRVLNKTGDIGI-AYADAGLIELPDGRRAVAAFVVKG +PFN-DPRSTELIRNMAAAM---- +>[subseq from] serine hydrolase n=1 Tax=Ruthenibacterium lactatiformans TaxID=1550024 RepID=UPI0006D7F522 +-qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERSAGRRAVSASTIKVFILLAALDEVR +RGRLALDTPVAVTAEDILPDTGVFVDGP--GHPLEELLVWMIVLSDNTATNVLIGLL-GA +ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYAETVLTPELCA +LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD +AP-DIDGDEPLAGRVSKLVFDYy +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis alba DSM 44262 TaxID=1125972 RepID=A0A229R8G9_9PSEU +--AISDEIEAVFANAGARGFVHAREVGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVA +AGRLDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDLVYHRI-GQ +DAVDKVLTDLGLTRTRLIGCCEDLFAVLDPERTTSSTPREITELLDAIWTDRAGDPAACE +RVRTIMAQQIW-PHRISSGFPAGVGIAAKTGTLP-AVRNEAGVVTQVDGRRYAVAVFTRA +DSDRLPAVDSAIGEAARLAVEH- +>[subseq from] serine hydrolase n=1 Tax=Spirosoma aerolatum TaxID=1211326 RepID=UPI0009ABB975 +--RLEQKLQSALAGFRGNAGVYVYHVRTGKRV-SINADTLFPTASMIKIPIQCGLFDKIH +KGELSYNQELVYKDSLHYDDGIVGSLKDGARITLSKVVMLMETISDNTGSLWCQALAGGG +TAINTWLETNGFHQTRVNSRTPGREANRSQYGWGQTTPRDMANLLLYLRQGNAVSPDASD +EMYRNLGRQFWDGDGL-SQLPPDVKVASKNGAVNQ-SRSEVVLVHAPHGD-YVYCVMTKN +QQERTNEGYALLRTVGSIVWHHf +>[subseq from] Serine hydrolase n=2 Tax=unclassified Subdoligranulum TaxID=2685293 RepID=A0A372V960_9FIRM +-qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERGAGRRAVSASTIKVFILLAALDEVR +RGRLALDTPVAVTAEDILPDTGVFVDGP--GHPLEELLVWMIVLSDNTATNVLIGLL-GA +ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYDETVLTPELCA +LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD +AP-DIDGDEPLAGRVSKLVFDYy +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter psychrotolerans TaxID=1524096 RepID=A0A4Y8S7P0_9SPHI +-kKLTAQLQTAVQGFKGQVGIYVQNLKTGKTV-AINQDTLFPTASMIKVSILSGLMDKLE +KGELKYNQKLAYRDSLLYAGEDILGSFKDKDIQLSKVAMLMITMSDNTASLWLQKLVTG- +THINNWLDSNGFKSMRVNSRTPGREAFRKVYGWGVTTPYEMCRLFTMIRNGQVVSPAASE +RMSRTLNRIYW-DNTALSQVPPYVQCLSKQGAVDD-SRSETVLVHAPHGD-YVFSVITKN +NKTPNNEADVLIRKVSALLWHYy +>[subseq from] Serine hydrolase n=1 Tax=Pedobacter sp. Leaf194 TaxID=1736297 RepID=A0A0Q5U4R3_9SPHI +-qKLQLKLNELVKGFKGDVGIYVKNLKTGKTA-SINADTIFPTASMIKVPITCGVFNKIE +KGELDYHAQLMYCDSLLYAGEDILGSFKDSEISLSKVLMLMITTSDNTASLWAQLLAGTG +TAINEVMANNGLKDTRVNSRTPGRKDNQKKYGWGQTTPKEMATLLALIRDGKMINPAASE +RIYRNLIRIYW-DSEALSQIPPTVQVASKSGAVD-AARSEVCLVNAPHGD-YVFCINTKN +QQNYSNEGWTMIRKLSNLLWNHy +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus erythropolis TaxID=1833 RepID=UPI000AFB9D8D +--SAQQEIAAVLAEAKTDAYVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA +AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL +DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE +EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS +HELT------------------- +>[subseq from] serine hydrolase n=1 Tax=Intestinimonas timonensis TaxID=1689270 RepID=UPI001031497C +-qALDTFLKQEIAAFPCKTAVLVGEVESGKVLwALEPDTQVVSASTIKVPVLLAALEEVR +QGRLSLDQTLDLPAEVLLEDSQVFEYG-PTSRSLWELLYWMIVESDNTATNRVISTV-GY +DAINAYARDLGLRHTVCQRQMLDWD-AIAAGRNNYTSAADQFALYRKLCRGEILNESLTA +VALDMLRRQRSMDDIL-RYNPYPVDFAHKTGGLDY-LSHDAGVFFQPGGD-WFLGIFTWD +GPEGDNRQKQFIGRLGKAIYDTy +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces olivaceus TaxID=47716 RepID=A0A1D8SRN5_STROV +--ATAARLDAAFADAGVTGWLHAVDIDSGAQT-GTGADQPVCTASVHKVCVLVTLHELAA +AGSLDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GR +DAVNRTTARLGLTRTRMAYGFGEMLAALDPARTNRGTPRDMTRLLGALWRDETCPAEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT +ANATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. 6K520 TaxID=2530364 RepID=A0A4R5EF83_9ACTN +---VTGRIEAEFRAAGVTGWLHVVDMDSGREV-AVRADAPVVLASVFKVPLLVAFHRQAA +AGVLDPAEPVTLDPGDRTAPTGISGMLDEVRMSLRDLTFLMITVSDNAAADAVLDRV-GR +DAVNAAAAALGLRDTVVEVSGRELHEALDPLRTSRSTPRDMTRLLSMIWRDEAAPPDGCA +AMRRLLGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGGRYAVAVFTRS +LLAVLPRADAVIGTAARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Actinocatenispora sera TaxID=390989 RepID=UPI00068EF62F +-----DEIRSVFTAAGATGFVHAREIGDGPSV-AVAADEPVVLASVFKIVVAVAYAREVA +AGRLDPRERATVTVGYRIGGIGTAGCGDDVQMSWRDLARNMLTMSDNAATDVVFHRV-GQ +AAVDAVLADLGLTHTRLCGCCTDLFAVLDPTRTTASTPAEITALLDAIWTDRAASPEACA +QVRAIMAEQIW-PHRLSSGFPDGVGIAAKTGTLP-AIRNEAGVVSYPDGRAYAVAVFTRA +SSQRQPAIDAAIGTAGRLAVEH- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E9UDW4_9CHLR +--KLVNSINNQVENFKGVAGVSIKDLTTGWYY-GINDELIFPTASSIKIPILLKLIESSE +TSKLDMLKNIEITEEMKSRGSGVIHKMNGTILTVENLAILMINLSDNTATNLCIDIA-GQ +DEVNKMLEDYEFVSMRLNRKMQDYT-AIKEGRENLSSVKEMNLILEMLDSAQAIKPEVAK +KVLNILSLNKS--TPISQPLPENIIVAGKTGGMP-GVRCETAIIYLANRK-YILTVMTSH +AGNGSSSSKQ------------- +>[subseq from] Serine hydrolase n=1 Tax=Ruthenibacterium lactatiformans TaxID=1550024 RepID=A0A3B9WE55_9FIRM +-qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERGAGRRAVSASTIKVFILLAALDEVR +RGRLALDTPVSVTAEDILPDTGVFLDGP--GHPLEELLVWMIVLSDNTATNVLIGLL-GA +ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYDETVLTPELCA +LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD +AP-DIDGDEPLAGRVSKLVFDYy +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Gordonia insulae TaxID=2420509 RepID=A0A3G8JPT2_9ACTN +hdRLTREVTAILADAGCAGWVHAESLGRPDHAfGAGADAPVVLASVYKLPLMISLCRMSD +RGELDMSEQVEVAPDEWSSATGLALLHDPVRMSWRDLATSMMTVSDNVAADVILTRV-GL +DTVLADLADLRLAHTRIVGGMRELHAAYDAAYSSASTPRDCTSLLAALWRDDVAVPETCD +FIRATMRAQVL-RSRLASGFPRHVAVAGKTGTLA-AIRNEIGVVEFPGEHPVAIAVFTKS +ARPSLPEVDRAIGRVARAVVT-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E0B742_9CHLR +--NLENTLVSKINEFEGVAGLSIRSLKNKNTI-SINGDEIFPTASSIKIHILTQLFSLEE +KGMIDLSKRIQFTQDMYGAGSGVIHFLENDPFSILDIAILMMLVSDNTATNMCIDLA-GM +KETNNLIKSFGLSKTKLGRKMMDAX-AINRGXENISTPNELTTMMELLYQKKP-SAKVSE +NVLXIMSKPKS--AYLNKAVGPNXKVANKPGGMDK-VXCXVGIVFLPNN-PYSISXMTNY +GXXDSLXQEAFIXXIAKTV---- +>[subseq from] Uncharacterized protein n=1 Tax=Microbacterium sp. Root61 TaxID=1736570 RepID=A0A0T2KX19_9MICO +-----DALLAAFAEVPVRGLIHAVDIDTGHEI-GVGSDESVVSASVFKVPVLVELCRQYS +SGRIDPRARIALGADERRTGSTGISVMLDELLSVRDMSLLMMSVSDNRATDVITDLV-GL +DNVNATMREFGFDRTVVDYDCDMLFAATTPEETDRTTPRQIAELLSAIWRDELLDADAAA +EVRRVMGLQAW-GHRLTAGFSPAVRVSGKTGTLFY-VRNEVGVVEFPTGERFAVAVFLQE +PTPRNPDADRVIGTAARLAVDY- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces kasugaensis TaxID=1946 RepID=A0A4Q9HTU5_STRKA +----LTRIREAFDGAGVTGRLHALDIDSGAEV-GASADHPVVTASVHKLCLLVALHQQAG +AGRVDLTEQIECPPAGRTPGPTGLAAMLDPVMSLRDAAYLMMAVSDNTAADLLLERV-GL +DAVNHTTARLGLAHTHAVYTFGETFGALDPVRANHSTPRDMTRLLAAIWRDEACAPAHAA +AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA +TNATFPPADAVIGTTARIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF65317 +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGILRALPRLTIKVEELLTLMIIVSDNTATNEFISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVILIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A374NXG9_9CLOT +---IEKRIEAELMSYDGTMGIYADDF-HGNVI-AIGADEPFETASTIKTYILACLFDQVE +KGKASLEDMVEFKEEHAVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL +DTINACIRGLGCRDTVLYNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPEADA +KMLEIFKKQHY-NSMITKDFPAVVNVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNKK +FSDAAHPATVFGARVSRMLFDQf +>[subseq from] hypothetical protein n=1 Tax=Acidisphaera sp. L21 TaxID=1641851 RepID=UPI00131B60AC +---VQSRIEAVLSPLGIEVGFAATHLQSGANV-AINPGILWPTASVFKVPVMVEVYRQAE +AGRFGLSDRMPMPDEQRTVGSGVMQKLAPGLPTIRDLVMLMTIISDNTATEMLLDLV-GA +EQVTATMHRLGLHDIHVVLNLPQLFAAFAMTAENTASAADMAKLMALIVQHEAGSAAACT +DMLAVLGAQQL-RDRVPRYLPARA-TANKTGTFK-GIRNDAGLMLRGPDDTIAFALFTFD +RT--------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Ruthenibacterium lactatiformans TaxID=1550024 RepID=A0A0W7TVC0_9FIRM +-qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERGAGRRAVSASTIKVFILLAALDEVR +RGRLALDTPVAVTAEDILPDTGVFVDGP--GHPLEELLVWMIVLSDNTATNVLIGLL-GA +ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYAETVLTPELCA +LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD +AP-DIDGDEPLAGRVSKLVFDYy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 150FB TaxID=1576605 RepID=A0A0C2BBP7_9ACTN +-----------------------------QEV-CVGADIPVVVASVYKLVALVAFCRAVD +AGELDPRQQVTVEPHRRTPPTGISALSDPVTMTWRDLATSMITVSDNAAADAVLERI-GQ +DRVRAVIEDLRLPGTRIHGGTAEAQRELDPTFGSATTPRDMTRLLTVLWRGEAASPEQTR +FARRLLEAQVW-PHRLRAGFPGAATVAGKTGTVG-AIRNEVGVITYPGEHPVAVAVFTHA +ARTDVPRADAAIGAAARHAVN-- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_1_40CM_65_14 TaxID=1803459 RepID=A0A1Q7GSQ9_9BACT +----ASRAGEIAAGLDGALGVSVFDYLSGFAW-GLDGDRWFHAASTIKVAILAGLFDAIE +RGRFTLDSRLHVRNRFLSVGQPFRHASIGKTMRVGELARHMIVRSSNLAANLLLDLV-GV +EETRAALAARDITGVDVCRGVED-ERAFEAGLSNRVTADGIVGLLRAIRDGRGFSPESSK +AMIDILMDQEF-AGGIAPGLPAVARVAHKTGDIST-VSHDAGLVFLPGRPPYVVAILAAC +AG-DPSARNEALAAISGLVYD-- +>[subseq from] Beta-lactamase n=1 Tax=Cyanobium sp. NIES-981 TaxID=1851505 RepID=A0A182ANF9_9CYAN +---LSQTWARLAAQKGLQASGFLLVLDDGRYA-ELQADQALPAASSIKTPILLASLEDVD +AGKIRWNEPLPLTKEVVGGGAGWMAKPVGTRFPFFESATEMIRVSDNSATNLLIKRLGGK +DKLNARFQALGLPATVINNWLPDLDGT------NTTSARDLAKAIALVDTGEKLSPRARD +LFREIMGTSRT-NTLIPLGLLQGITVYNKTGDIGI-AYADAALIHLPNGQRAVAAFMVKG +PFND-PRSADLIRSMAA------ +>[subseq from] Secreted beta-lactamase n=1 Tax=Streptomyces lividans TK24 TaxID=457428 RepID=D6ENE9_STRLI +----AARLDAAFADAGVTGWLHAVDIDSEAQV-GAGADQPVCTASVHKLCVLVTLHELAA +AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL +DAVNRTAARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLGAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Carboxylesterase, beta-lactamase family protein n=1 Tax=Synechococcus sp. (strain CC9311) TaxID=64471 RepID=Q0IBJ5_SYNS3 +--ALSKRWQALAAKDDLQVSAFMLALDDGRYA-QLNPDTALPAASAIKTPILLVAIEEID +AGRLSWNEPLTLSKTVVGGGAGWMAKPLGTRFPTYEVATEMIRVSDNTATNLLIERVGGQ +ADLNARFNSLGLSATKVNNWLPDLKGT------NTTSARDLARAIALVDTGEVLSIRGRD +LFREVMGTSVT-NRLLPGGLLKGYRVFNKTGDIGI-AYADAGLIELPDGRRAVAAFVVKG +PFN-DPRSTELIRNMAAAM---- +>[subseq from] Beta-lactamase class A n=1 Tax=Sinosporangium album TaxID=504805 RepID=A0A1G7X7F8_9ACTN +--SVEQEIRDIFTEADAEGFVHVREVDGDGEV-GVLPDAPVVLASVFKIPILLEYARQVA +KGTLEATERLTVTAEYRDGGIGTAGCLDDVSLTVRDLAHFMITQSDNAATDVLLRRV-GL +DNVHATLRGLGLDRTRLIGGCQELMAVRDPEQTTSSTSRETTSLLAAIWREEAGPAEACA +EVRRIMYNQVW-PHRLSSAFGDEVRIGAKTGTIM-GIRNEAGVLEFPDGARYAAAVFLRP +RGVRLPKADAAIGEAAKAAIDH- +>[subseq from] SH3b domain-containing protein n=1 Tax=Cyanobacteria bacterium UBA8530 TaxID=2055790 RepID=A0A355UTW5_9CYAN +-----ARLAEIAD-RGGRVSIAFHHLDSGEKW-AWRGEKTFPAASLIKLPLMAACYRLAG +AGKIFLNERVLLSEAVGDGKEPFDDAPLGEYFTLRKLIDRMITESDNTATNTLLERI-GF +EPVRELLDAWGLKETKLERKMLDWESR-RVGRENTTTAEDMLSFLLQLQRGDDFPSAWKE +EMWGLLTHQRD-KTKMARRLP-HLDLAHKTGEIPN-IRHDVGRIKATNS--FLLAVLTEN +LE----KANTVIGRLSEAIVRHy +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharomonospora cyanea NA-134 TaxID=882082 RepID=H5XFB7_9PSEU +------------EATGVHAQVHARCLATGRQT-GVGSGERAVLASVVKVPLVLEFARQVA +AGQLDPADRVRVSAEDRLGGTGTAGCADDVELSLRDAAFLAMSVSDNSAADLLFDRV-GV +DNVQALVTELGLTATRVVCPPRDVVRALDPAHTNAGTPEEMTRLLELVWTDRAGPPESCA +AVRRWMAQQVN-WLRLGSAFPAEASVAGKTGTLPC-VRNEIGVVTYPDGGRYAVAVFTRV +ASGRRPDIERAIGLTARAAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces triticagri TaxID=2293568 RepID=A0A372M6J2_9ACTN +---ATRTIRELFADAGVRGWLHVAELHREARV-TIDPDEPVPMGSVYKVPLMVAFWRLVD +AGTLDPRSSLTLEPAHRIAPTGISILQDPVTMSLRDLVVLMMTVSDNSAADAVLRTV-GA +PKVDEVCRELGLPDTHVLGGVANTWAVYNPASKSSTTPADMARLLREIWTGRAASAEHCA +LMREVMGRQAW-RHRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELADGSTYTAVVFTRA +ARADLPRADAVIGAAARVAVE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. A1547 TaxID=2563105 RepID=UPI00144A4EBC +----LHRLRAAFAEAGVTGRLHAVDIDSGTEI-DAGADQPVVTASVHKLCLLVALHEHAA +AGRVDLGEQVECPPGDRTAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL +DGVNEATARLGLTRTRAVHTFRSLFAALDPAHSNRSTPRDMTRLLAAVWRDEACTPEHGA +AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-LRNEVGVIEYPDGGRYAVAVFTRA +ANATLPAADAVIGTTARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. UW179B TaxID=2575516 RepID=UPI000E0E26ED +--ALSKRWEALAAQDDLQVSAFMLALDDGRYA-QLNPDTALPAASAIKTPILLVALEEID +AGRLSWNEPLTLSKTVVGGGAGWMAKPLGTRFPTHEVATEMIRVSDNTATNLLIERVGGQ +VDLNARFNSLGLSATKVNDWLPDLKGT------NTTSARDLARAIALVDTGEALSIRGRD +LFREVMGTSVT-NRLLPGGLLKGYRVLNKTGDIGI-AYADAGLIELPDGRRAVAAFVVKG +PFN-DPRSTELIRNMAAAM---- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6GCJ3_9BACT +-------------------------LETGFRF-SFRGDRWFHAASTIKVAVLLAVFRAAD +EGQFRLDDSLHVRNRFFSAADGSLYAAIGRTAKISSLAYAMICGSSNLATNLLLEFV-GV +EYARKVLGGAQVDGVELRRSVEDH-GAHEQGINNEATADGLLRLLS-VIRGDFLTPESKR +EVIRILLEQRF-NSMIPAGLPPHATVAHKTGETST-ACHDIGIIYLPEREPYIAAILTEF +DP-EREGRRETVAAISQAIYR-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8NHG2_9BACT +--SLDAQVRAETAQFKGKVSLFARNLDSGESY-SLNGDERVPTASTIKIAVMIETFARVA +EGRAKWTDELVLTKAARYGGSGVLPELSDGLLTLRDCVNLMMLVSDNTATNMVLDYL-TT +DAVNARMDSLGFKQTRIMRRVGGGGESKDGKVADATTPHEMVQILDKLDRGEVISPAASK +EMLDLMKREQA-RYAIGRTIW-SVPMASKYGALDH-LRSCLAIVYSKRGR-TAIAITVDE +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Salegentibacter sediminis TaxID=1930251 RepID=UPI0009C157C1 +-tQLQQKLERYTKDFRGTAGVYVFNTKTGKQA-GVNADTIFPTASIVKIPILVGLFDKIN +EGELNLNDSLIYRDSRQYGGSGLMQFYKDSTTDLRTLAALMITYSDNVTSIWSRELAGGG +ESINPLMEKLGMKHTRVNSKTRGREKNWEKYGWGQTTPREMATLLVKIRNREVVSNAASD +EMYRMLSNSFY-TDYALSQIPPYIQTAAKQGMVNK-SRSEIVLVNAPFGD-YVFYIATKN +NLDTGNEAWELQRNISAMLWNYf +>[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1M6R1L0_SELRU +--DLQANTARIIGDSVNQMSVYFLRPDREMEP-FLYNQRQLSPASIIKLFVMAKTMQDVH +DGKLNLTDKITIRKKDVVGGAGVLTWYDAGQRTVLQLLTVMITDSDNTATNLLIDRLGGM +KSINQYLAQYGYTDTVLAHKMMIGN----GGRKNLSSVRDLGHLLTRLYYHQLVGPEEDE +IMLDILKQQHD-KECLGSALP-EYVIAHKTGEVT-GVYADGGVFFGQNED-FILVILNNG +TEGRV------------------ +>[subseq from] Possible beta-lactamase family protein n=1 Tax=Synechococcus sp. BL107 TaxID=313625 RepID=Q067T7_9SYNE +------WIQQAATQPDLQVSAYMLILDDGRFA-QMNAHRPMPAASSIKTPILLAVLERID +QGTLQWNEPLTLTKELVGGGAGWMASRPLGSFPTYEVATEMIRVSDNSATNLMIARAGGQ +DAINARFQALDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGESLGPRSRD +LFREVMATSVT-NTLLPTGLMRGYRVFNKTGDIGT-AYADAGLIELPDGRRAVAGFLVKG +PFN-DPRSTEMIRQLAAAMA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3C1YU45_9BACT +-dSLRNKIERIVHQNEGHIGVAVINLNSNDTV-MVNGKEKFPMQSVYKFPLALAILHQID +KEKLSLDQRIHISKSDLLPWSPLREKYPDGNITLDEILTATVAWSDNNGCDLLFRLVGGP +TMVDQYIRSLGIEGMAIVSTEEEMH----------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) TaxID=479432 RepID=D2ARC0_STRRD +------ALREAFDDADVEGFIHVRDVDGDAET-GLGADEPVVLASVFKVPIVLEYARQAA +AGTLERTERLTVTAADKDGGIGTSGCADDVSLTLRDLAHFMMTMSDNAATDVLLRRV-GL +GNLHATLRGLGLERTRLIGGCAELLGILDPERTTSGTPRETTTLLTRIWRDEAGPPEACA +EVRRIMGNQIW-PHRLSSGFGDEVKVSGKTGTLW-GVRNEAGVVEYPDGRRYAVAVFLRT +GSLRLPRADRVIGHAARVAIDH- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis coloradensis TaxID=76021 RepID=A0A1R0KFC1_9PSEU +--AIADEIEAVFAGAGARGFVHAREVGDGPEV-GVGADDQVVLASVFKIPVAVAFAREVA +AGRLDETDRTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDLIYHRV-GQ +AAVDQVLADLGLARTRLVGCCEDLFAVVDPERTTSLTPREITTLLDAIWTDRAGDPAACE +RVRTIMAQQIW-PHRMSSGFPAGVTIAAKTGTLP-AVRNEAGVVTDVDGRRYAVAVFTRA +ESDRQPAVDSAIGEAARLAVAH- +>[subseq from] Class A beta-lactamase n=2 Tax=Muribaculaceae bacterium Isolate-002 (NCI) TaxID=2489215 RepID=A0A4Q0J1G6_9BACT +---LAGNIQDYADASGAEIGVAVIGSDGDTTV---VNDGYYPMNSVLKMFQALPAAKKLS +ERGVMLCDTVEVERSVLQQWSPMLTDYTDPVLPYARLFEYALAQSDNNACDILFERAASI +DETLAYWRQAGIGEFDIKWNEAEMHDAPVRSDDNRTTPLAAAKAISVMMPYCMTSSDYNT +SNIGMMLNCSTGKGRIPRPLETGAQVAHKTGTGFEDGVNDVAWILLPDGRAYTLAVFVKT +TPACMAQTEAMIADISRIVYDYy +>[subseq from] serine hydrolase n=1 Tax=Pseudoclavibacter sp. CFCC 13796 TaxID=2615179 RepID=UPI001300CEDB +-------IVDSAAQHGVKMGIALGDLSGGESVaVGAADEEFKAASTIKIGLAAVIMRAVD +DGRWDLQTPVTVRPSDIVGGTGTLQGGAAATLPLGELLRLMITVSDNTATNVLIDFVGGL +DAVGVGLRALGIADADMHRKMVLSH---DARHENLITATGDMRLLERIHAGEMLSRAASD +QIIDWMRQQTV-NTKFGAVVP-RTELANKTGENVD-VSHDTGYLLTPGRE-VALAVMTSF +GPGTASAADRDVQDVARAVHD-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus cereus HuB1-1 TaxID=1053207 RepID=J9B8Q8_BACCE +------------------------------------------------------------ +-------------------------------MILKELADASLQYSDNNAQNLILKQLGRP +REFQNSMREIRDAVTNTERFKSELNVVHPGDAHDTSTPKALATSLQNFTIGDVLSTEKRD +LLIDWMQRNTTGDNLIRAGVPGGWEVADKTDLESYGIRNDIEIIRSPNN----------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. NEAU-CX67 TaxID=2571143 RepID=A0A4U0QM80_9NOCA +--------------------------DDEDAV-SVGADELVVTASVYKLPLLVALCRAFD +AGSLSPTATVRINPADCTPPTGVSNFRDPVVMSWRDLALSMMTVSDNAAADLILGRV-GL +DGIDRVLAELGLLRTRIIGGTADVHRAYDPAFTSATTPREMTSLLDAIWTDGVVSADQAQ +FIRQVMAGQIW-PHRIRSGFPAGVTVAGKTGTIG-AIRNEVAVVGFPGETPVAVAIFTRA +ARADLPVVDQAIGRAAHIAVT-- +>[subseq from] CubicO group peptidase (Beta-lactamase class C family) n=1 Tax=Rarobacter faecitabidus TaxID=13243 RepID=A0A542ZNW4_RARFA +-----------AATKNVRMGISVTDLAGGDTI-TVGDQEPYKAASVIKLPLLALLMDLAD +KGQLSLDESVTIPASNIVGGSGTLRLREPLDITVRELMELMVQVSDNTATNVLIDRAGGF +DAINEYIDGLGYDTMWLGRKMI--HTAVPPLQENWLNSSEVTDFLVRLYDHDFLSASSSE +HIIDLMKGQLV-NTKFGAVIPRD-VLANKTGELGD-ASHDSGYILIDGRE-VALTATTAF +SAFTLAEANVYVQRAATFVYD-- +>[subseq from] serine hydrolase n=1 Tax=Gelidibacter mesophilus TaxID=169050 RepID=UPI0003FEB316 +-kNLEKGLAELVKTFEGDVGIYVYNLKTDKEA-AINADTIFPTASIVKVPILIEVFNQIK +VGKLRYNDTLVYDAKRKYGGSGLMQFYKDSTTDLRTLTSLMITVSDNTTSLWCQELVGGG +LAINKTMADLGLTHTRVNSRTEGRTKDWEIYGWGQTTPREMASLLIKMRKRTLVDETSSD +EMYRLMTNSFYTDYSL-SQIPPYVQTAAKQGMVNK-SRSELVMVNAPHGD-YVFYIASKN +NTDEDNKAWQLQRTISAYLWHYf +>[subseq from] Secreted beta-lactamase n=1 Tax=Kibdelosporangium sp. MJ126-NF4 TaxID=703222 RepID=A0A0K3BS50_9PSEU +------EIGAVFANAGARGFVHARQIGGGPEV-SVGADDQVVLASVFKIPVAVAFAREVA +AGRLDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDLIFHRV-GQ +AAVDQVLADLGLERTRLIGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACE +RVRKIMAQQIW-PHRISSGFPAGVAIAAKTGTLP-AVRNEAGVVTDVDGRRYAVAVFTRA +ESDRLPAVDSAIGEAARLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Spirosoma agri TaxID=1987381 RepID=UPI0013DA8014 +--SLDRELTTALAGFHGTIGVYVRNLRTGETV-AINADTLFPTASMIKVPILCGLFDKIH +KGELAYDQQLVYRDSLHYDDGIVGSFKDGTKLALSKVAMLMITVSDNTGSLWCQALAGGG +ATINQWLDTNGFHQTRVNSRTPGRAANQAQHGWGQSTPRDMADLITYIRQGKAVSPDASE +EMYRNLGHQYW-DNDGLSQIPPDIKTACKNGAVNQ-ARSEVVFVHAPHGE-YVYCVMTKN +QKDETNEGFVALRNIAAILWHHf +>[subseq from] serine hydrolase n=1 Tax=Microbacterium sp. dk485 TaxID=2560021 RepID=UPI001431CA46 +------------TAAGVDLGVAIEDLSDGRSL-FAGKQDRSTTASTIKMALAVTVMQQVE +AGMLTLDDIRTILPEERYEGSGILKDTFPQDVSIGRMLDLMITVSDNTATNKLVDVVGGF +GPINATIESAGVPRTDLHFGRKMFGGIVPPDGDLWLTPSGMNELLTRIYEAAFLSAASAE +HIIDLMLAQQV-KTKLGATVPAG-ILAHKTGENAE-VSHDVGMVLLPGQ-EITLSVFSTV +RPDVQAVANPFLQRIGTAVHDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Lentzea waywayandensis TaxID=84724 RepID=A0A1I6F884_9PSEU +-----------FAEAGVEGFVHAREIGDGPEF-CHGADDQVVLASVFKIPVAVAYAAEVA +AGRLDETERTRVTSRYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDVVFHRV-GQ +ATVDAVLDRAGLERTRILGCCEDLFTIVDPERTTSSTPREITTLLDAIWTDRVARPEACE +RVRAIMAQQIW-PHRLSSGFPADVQVAAKTGTLPS-VRNEAGVVTYPDGHSYAVAVFTRS +QSLDDPAADAVIGRAGRLAVDQ- +>[subseq from] Serine hydrolase n=1 Tax=Terriglobus albidus TaxID=1592106 RepID=A0A5B9ECM8_9BACT +------AIRGLVAAHHGKVAVYARQLNTGKVI-AVDEDVPVQTASVIKLTMLYEAMEQIR +DGKAKWDEKIVLKPGDAVSGSGVLTFMDPPKLTLKDVLTLMVILSDNTATNLAIDRF-GV +KAVNDRIHALGVKDTHFYKKVMKPATDQPKFGLGKTTAHEMATVMEKIGRCDLGGPSQDE +AICQTMLRNQFYRNTIPRYLEAGSAIASKTGSLN-AVRNDVAIVAAKSG-PIVISIFTWQ +NKTTDNEGEGTIARIAREIVQEw +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora antimicrobica TaxID=455193 RepID=A0A1I4SHB7_9PSEU +-----------QAELPGRVGFAAWDLTEREPV-LLGAERVVPAASTIKVLIMISALRAVQ +GGRIGLDDEVELPA-QRVGGAGLLRLLRSVDISLRDLITLMIVVSDNAATNAVIDAV-GF +AAIRDCAADLGCTDTRVERRLMHHHEP----GRNETTALDQARVLDRLAGGTALPPELTE +HALGVLAEQQV-RDRLPALLPVGANCWNKTGELL-GLRHDVGLLGTD-RPQAVIAVLVDE +LTDE------------------- +>[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. H219 TaxID=2492662 RepID=A0A3R8P0V0_9PSEU +--SVERRIRAVLADAGAQGWVHAVRLGAGEHElGIGADELVVTASVYKLPLLVALARAFD +AGVLDPRETIRLDPTSCTPPTGVSIFQDPVRMSWRDLGASMVSVSDNAAADVLLGAI-GL +EAVADTLADLGLDRTRVVGGTADAHAAYDPSYASATTPREMTRLLELIWADEVASPQQCA +FVRRLLGQQAW-MHRVRAGFPQGVRVSGKTGTIG-AVRNEVSVVEFDGESPVAVAVFTLA +ARADLPRVDAAIAECARIAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Parapedobacter composti TaxID=623281 RepID=A0A1I1KKM6_9SPHI +--KLQRALEDAAKNFRGDVGIFVRHLKTGKEA-AIHADTVFPTASIIKVPILVGLFDKIW +KKELDYRQELLYSDTLYYGGSGLMQFYKDSATDVSVLASLMITYSDNVTALWCQHLAGGG +QTINALMDRYGFVHTRVNSRTPGREDARRAYGWGQTTPREIAMLLTKIRLGEIVSQTASD +RMYRLMTNIYY-DEGALSQIPGTVASASKQGMVN-ASRSEVVLVNAPSGD-YVFSIMTKN +NTTHDNEASELIRTISSLLWNHf +>[subseq from] Serine hydrolase n=1 Tax=Kribbella albertanoniae TaxID=1266829 RepID=A0A4R4PQQ6_9ACTN +----NARIRATFADAGVRGWLHAVALDAPESTvDIDADTVVPMASVYKLPLLVGFCRLVD +EGELDPRERLTLDPSTRTPPTGVSLMADPVTMSLRDLAVSMMAVSDNAAADALLDVV-GL +DRLAELLQSFGLQQTWVRRGTAANLVVYEAANASATTPSDMTLLLRRLWTGELLSAAQTD +FAKATMRRQIF-QHRLASGFPDSIRVAGKTGTFG-ALRHEVGVVTLPAGDAYAVAVFTLT +ARSDQPRADATIGLAAQLAV--- +>[subseq from] Serine hydrolase n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A3B9YJX0_9BACT +-eSLQARMEALARAHRGQVRFYAKSLATGESV-ELDADEPVRSASTIKLGILVEAFHQAG +EGRLPLSGKVVLREEDKVQGSGVLKFLRAPLLTLEDVLTLMVIESDNTATNLAIDQV-GL +NAVNARFAALGLKNTRLYKKVYKPAEPLPPDQKEFGLGKTTAREMSRLMEEAARDERMTA +ILKGQQNRNMI-PRYIEAGLDGGAIVANKTGALD-AQRSDVGAVFSPAGT-ILVSAFTDG +NEDQENEAEGLIAQLAKTVFDSw +>[subseq from] Serine hydrolase n=2 Tax=Cupriavidus sp. TaxID=1873897 RepID=A0A356HK75_9BURK +--RVETALAPLLAGTQARVAISLR-LADGKVVlEREAERVQPSASIIKLPILFTLLEQVA +QGHLQLEQRFSLDGLERVGGTGILSQLPSVQLTLAELARLMIVLSDNLATNALIELL-GF +EGVNDWCDRAGLRQTRLQRRMMDAAAR-AAGLDNFTSASDAAASLCWLLRDGSLPAPLRD +FALGLLADQRE-RAHFGAALPAGAMLANKTGQLP-GLRHDAGILTVGAY-SVVLAVLADG +FTDA-RTAQ-------------- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E6MLA8_9BACT +-eHLHSELSSIAERYEGVAGIHVLDLSSGDRF-AVRDDFIFPQASAIKIPILLELFRRAE +SDPGLLSKRIEMTEEVRTSGSGVLDVLTDGGLSLEDYAIYMILHSDNTATNILIDEL-GM +GPINALSASLGAPNTLLQRKMIQPEES-ARGNENLSTPRDAAEIMKRIANCELMSEIACA +RVIEILSIPKGG--PIRRPVPNAIPIAFKPGGIT-GVATVWAIVDVPDR-PYVITVMSNY +GG----DGGAVIEAAQKAAYSYf +>[subseq from] Beta-lactamase class A n=1 Tax=Ktedonobacter racemifer DSM 44963 TaxID=485913 RepID=D6TNC4_9CHLR +-------------ALSGEVACVVWSPSTPEPLyTLHASQRFPAASLAKLPILLTVARQVA +QGKLAWEMRYEVPAAMRVTSDGVLTDLSPELPTLSDLAYLMITISDNTASNILLDLA-GM +EHINAFMQELGLHVTRLERRFMDFTAR-QQGRDNWTNAEEMARLLAYLCSEAA---PERE +RLLSILLRQND-YTILPSSWSEEVPFAHKTGGLV-GVMHDAGILYPPGKAPLILVALTAN +QA-DTPHTRYTLSRLGKLIYENy +>[subseq from] serine hydrolase n=1 Tax=Streptomyces rubrogriseus TaxID=194673 RepID=UPI000D59A408 +----AARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVTLHELAA +AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGSVWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Saccharopolyspora antimicrobica TaxID=455193 RepID=UPI000B8309ED +-----------QAELPGRVGFAAWDLTEREPV-LLGAERVVPAASTIKVLIMISALRAVQ +GGRIGLDDEVELPA-QRVGGAGLLRLLRSVDISLRDLITLMIVVSDNAATNAVIDAV-GF +AAIRDCAADLGCTDTRVERRLMHHHEP----GRNETTALDQARVLDRLAGGTALPPELTE +HALGVLAEQQV-RDRLPALLPVGANCWNKTGELL-GLRHDVGLLGTD-RPQAVIAVLVDE +LTDE------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudacidovorax sp. RU35E TaxID=1907403 RepID=A0A1N7D284_9BURK +------------------------------------------------------------ +---------------------------------------------------------NGP +ARVEAIRRAVDAKRTDLATTMDEAYDRYYRRDLNTTTLIAYGGMLERLVRGQVLPDPPRA +VLYKAMKHDIYTGYRLQAGLPRDHAFIHKTGTQHR-RACHAGVLDPDDLQKALVIVACTA +DLDEQKQAGPVLESVGRAIR--- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. XM-24 TaxID=1979185 RepID=A0A316JLL3_9SYNE +--ALSKRWAQLAAQYDLTVSGYLLVLDDGRFA-ELAPQRPLPAASSIKTPILLVALEDLD +AGKLRWDERLPMTKEVVGGGAGWMAKPVGTTFPFWEAANEMIRVSDNTATNLLIKRVGGK +AVINARFQALGLSSTVVNNWLPDLDGT------NTTSAYDLARSIALVDTGEKLSPRARD +LFREVMGRSRT-NTLLPLGMLMGVTVYNKTGDIGI-AYADAGLIELPDGKRAVAAFMVKG +PFND-PRSTNLIRAMA------- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A6A7LVA9_9CHLR +-nELAADVVQRIAGLSGQVGVAIKELDTGRGT-SIDPDGEYEAASLYKLPVMYEVFKQRE +LGALAFDESLVFTQRYVDWDLGTLDRPVDSTITIDEALEQMITISDNSSAVLLTDRV-GA +LNINRDLLGLGLAHTRLVTDDLAM------------SPGDALTLLEMIARGHAVNPAASA +EMVDVMARQRV-NDRLPLLLPDSTVVAHKTGNLP-GVVNDVGIVYTPET-TFIIAVLIDG +TA-NEQAAAEAIADLALIAYRHf +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A2G4GM14_9BACT +--RLQVEVENLVKGHQGEIGVFIKELKSGKTV-AVNAETSFPTASIVKVPILIGIMNKIN +NKVLDYHQKLTWYDTLNYDVDIVAYLKPETQIELSKVMMLMITISDNTASLWLQRVAGTG +TVINALLDSLGYAHTRVNSRTPGREANRTEYGWGQTTPIEMAQIYEDIVNGKVISREVSN +RMLRIMGRQYW-DGEALSAIPPDIYVAAKSGAVDA-SRSEV--LYVKGKRPYILSVFTKN +NKEDANEAWELTRSLSKLVWNYy +>[subseq from] Serine hydrolase n=2 Tax=unclassified Rhodococcus TaxID=192944 RepID=A0A149ZQK7_9NOCA +-------------------------IDDGGDI-AVGADDLVVLASVYKLPLLVALCRAFE +SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLAMSMMTVSDNAAADLVLGQV-GL +ESVERALSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE +FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA +ARTDLPVVDAAIGHAARIAVT-- +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. KCTC 15687 TaxID=2447885 RepID=A0A401LUF6_9BACE +------------------------------------------------------------ +-------------------------------MSIADLLRYTLQQSDNNACDILFHYQGGP +KAVNDYIHSLGIRDCAIVATENDMHQDLDLCYQNWSTPLAAAELLEIFRKKELFANKYKE +FIYQTLVECQTGQDRLVSPLAKGITIGHKTGTGDRNGCNDIGFVTLPNGRSYSIAVFVKD +SEENSQTNSKIIAEVSRIVYEY- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. BJA-103 TaxID=1911175 RepID=A0A2N8MT44_9PSEU +--ATTDEIEAVFAKAGARGFVHAREVGGGPEV-CVGADDPVVLASVFKIPVAVAFAREVA +AGRLDETERTRVVARYRIGGVGTAGCADDVEMSWRDLAHFMLTMSDNAATDLIYRRV-GQ +EAVDRVLADLGLARTRLIGCCEDLFAVVDPDRTTSSTPREITELLDAIWTDRAGDPAACE +RVRTIMAQQIW-PHRISSGFPAGVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA +DSDRLPAVDSAIGEAARLAVEH- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus xianganensis TaxID=1507289 RepID=UPI00132297D3 +-------------------GLRVTDLNGTELV-AWNAEWVFPAASTIKVPLLVFALQEAQ +AGRLDLSARVTVRPGDRVPGAGVLHDLDGGLLTWRDVLTLMIVVSDNTATNLVIGRL-GV +GTVNAWLAAQGLTGTRLVGKLEQRNEAQRRGERNATTARDQTALLRVLVGGELLDGTHTA +LALDILGRQQY-RDLIARHVPCGYRSATKSGELL-GVHHDVGVLFTP--RPLLVALLSEG +GADPRE----------------- +>[subseq from] Putative beta-lactamase n=2 Tax=Synechococcus sp. RS9917 TaxID=221360 RepID=A3Z7S2_9SYNE +--ALSQRWRALAAEKDLQASAFLLKLDDGRYA-ELSPDTALPAASSIKTPILLVALELLD +AGDLSWNEPLTLSKTTVGGGAGWMASPLGSRFPTHEVATEMIRVSDNTATNLLIERVGGK +ELLNERFNALGLSATVVNNWLPDLEGT------NTTSARDLARSIALVDTGEVLSTRSRD +LFREVMATSRT-NRLLPGGLLKGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG +PFND-PRSTELIRAMAAAM---- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E8QT65_9BACT +-dSLQSRVAARLDRLXAIXSIYAKHIPTGREI-AVRADHPMNTLSVIKIPVMVKAFQDNA +SGRLDFGERYTVGPNDMRRGSGLIQTFEPGLPTLRSLVTQMIITSDNTATDMVIKAV-GL +DRVNALLQNEGFSQTRLKATTGDLFRAFEGDSTGKTTAREMGNLLEQILNAELADEEASA +EMIAMLTRQFY-TSRLPQRVRQGVSVAHKTGDWPPIAGNDVGILFYEGG-PSIVSVFTNQ +NTGDFFDLEATLGLIAEDIVEAw +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobiales bacterium TaxID=2026801 RepID=A0A3D4EUJ7_9BACT +--TLATKLETRVAELDCEVGLYVQHLKKDHSV-LINADEVFPAASLIKVPILASLLNKVE +RGELGYQDKLIYTKDRLYPGEDLLGSFANNELTLKKLVFLMITTSDNTASLWCQELAGTG +TTINTWLKEKGFLRTRLNSRTPGRAAARGRYGWGQTTPREMAQLLIHIRDRKLVSAAADE +EMARIMGRSYWDGEAI-SSVPPSISTMSKQGAVN-ASRSEVVLVHAPHGD-YVFCIITKN +QKKHDNEGFSLLRDISRILWEHf +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. 111WW2 TaxID=1945515 RepID=A0A2P7ZJ36_9ACTN +----AARLDAAFADAGVTGWLHAVDIDSEAQV-GAGADQPVCTASVHKLCVLVTLHELAA +AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL +DAVNRTAARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLGAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. WH 8101 TaxID=59932 RepID=A0A4P6L9F5_9SYNE +--ALSQRWRALAAEKDLQASAFLLKLDDGRYA-ELSPDTALPAASSIKTPILLVALELLD +AGDLSWNEPLTLSKTTVGGGAGWMASPLGSRFPTHEVATEMIRVSDNTATNLLIERVGGK +ELLNQRFNALGLSATVVNNWLPDLEGT------NTTSARDLARSIALVDTGEVLSTRSRD +LFREVMGTSRT-NRLLPGGLLKGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG +PFND-PRSTELIRSMAAAM---- +>[subseq from] serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=UPI000E168597 +------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE +EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM +DKINETIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ +MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG +IPNS-VYGTVTLAKYGKMTWD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacteroidetes bacterium HLUCCA01 TaxID=1666909 RepID=A0A0P7ZBE9_9BACT +-eTLEENLQQRIADFNGDAGVFVHHLPTGREI-SIQGDTLFPTASMIKVPLAVRIAELVE +DGSLHYDSLHTYEDRLYYPGSDLVASMKAGEIDLRKMVFLSLSFSDNTASLWMQELGGTG +TMVNEAMARLGLEHTRVNSRTEGRQEDFRRYGWGQTTPREMTRLMEMIYRGEVINPERSE +ELYRLLSKTLW-DGTALAVIPVTVNVASKQGAVS-ASRSETAVVNAPSGD-FVFTVITKN +QQDDDNEGFELIRDVTRLLWEAf +>[subseq from] serine hydrolase n=1 Tax=Oceanobacillus rekensis TaxID=937927 RepID=UPI0011239ECC +-nELETALRALTKEVASKFSIAVH-TDEG-SI-AINVRTPRKAASLAKLFILGEAYQQVE +ATQISLDKLVYITPKSMVEGSGVITYLTDAHFSYQNLLELMIIVSDNTASNILLDTI-GM +EYINHFATKIGCNHTSLQRKFMDQKSHL-QGNENVTTSADIICLLKLFSRNDFFSNDSRK +QILNTLGNQQF-NSKLSTYINTSIKIYHKTGELHS-VEHDAAIMEANGN-VLEVAVLTDG +WE-NNGDASKYMAEIGRLLMNY- +>[subseq from] serine hydrolase n=1 Tax=Longispora albida TaxID=203523 RepID=UPI0003617514 +-eDLRHHLGSLFAGAGVTGCLHAIDLDNGREA-GLGADTPVLMASAFKLPLVLALFRAAD +TGLADLAGQVRLEPGTRTSGPTGIGAMTGPVMTLRDLAHQALSVSDNAAADAIADHI-GL +GALTATAEAAGMAATRIAEICRDVAATLDLTASNRTTARDCTTLLAGIWKDTAASPGSCS +AIRHLLSLQVW-PHRLASGFPDDVRVAGKTGTLPT-VRNEIGVVEYPDGGRYAIAVFTRS +AALNLPRADAVIGTAARTAVEY- +>[subseq from] Serine hydrolase n=2 Tax=Clostridium perfringens TaxID=1502 RepID=A0A317TD26_CLOPF +------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE +EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM +DKINKTIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ +MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG +IPNS-VYGTVTLAKSGKMTWD-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Omnitrophica WOR_2 bacterium RIFCSPHIGHO2_01_FULL_49_10 TaxID=1801852 RepID=A0A1G1NFT2_9BACT +-------LEREVAAFKGEAAIVVKDLDTGSEI-AFNKYNKYPSASLVKIPIMFAAFSAAQ +EGRLKLDKAVAVKAASKTGGSGVLKNFTPGTVTVKELIELMITGSDNTATNMLIDLL-GF +DYLNTYFTKIGLKSTNLSRKMMDFDHR-KKGVENYSTADDMSILLEKLYRNELFNEEITK +QCMAFLKNQRH-NDRIPA------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. BL107 TaxID=313625 RepID=UPI0002E4CE7F +------WIQQAATQPDLQVSAYMLILDDGRFA-QMNAHRPMPAASSIKTPILLAVLERID +QGTLQWNEPLTLTKELVGGGAGWMASRPLGSFPTYEVATEMIRVSDNSATNLMIARAGGQ +DAINARFQALDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGESLGPRSRD +LFREVMATSVT-NTLLPTGLMRGYRVFNKTGDIGT-AYADAGLIELPDGRRAVAGFLVKG +PFN-DPRSTEMIRQLAAAMA--- +>[subseq from] serine hydrolase n=1 Tax=Lacrimispora aerotolerans TaxID=36832 RepID=UPI00054F0BBB +-----AEMVKRLEQLPGKVSFYFENLMTGETM-VYHEQAPMMAASVIKLFVMTSVFEGLE +RELFQPDQMFEIKRADCVPCGALTYLHNGIQVTLMDLVTLMIIFSDNTATNVLVDFM-GM +EFINETISRLGFEKTVLQRKMFDLEKS-KQGIQNYITAGETGRLLNMMYHGDLVSRHASE +RMVSIMKNQQL-SGKIPFYLPDRPKIAHKTGEDT-GISHDVGIIYGK--VPF-IVCYCGN +ET-DTPCFERFMAELSLELYQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2541 TaxID=2512217 RepID=A0A4R2IHD5_9ACTN +----NARVRAVFEDAGVRGWLHAVALDEPSATvEVDADDIVPMASVYKLPLLAGFCRLVD +LGEVDPTEQLTLDPSARTAGPTGLSALADPVMSLRDLAVSMMTVSDNAAADALLDLV-GL +RRLASMLESFGLRRTWVRRGTAGHLRVYEAANASASSPRDMTLLLRLLWAGELLSAEQTS +FVQATMHRQVF-QHRIASGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGAAFALAIFTQA +ARGDQPRVDAAIGEAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Microbacterium wangchenii TaxID=2541726 RepID=UPI0014319951 +------------TAAGIDLGVAIEDLSDGRSL-FAGKQDRSTTASTIKMALAVTVMQQVE +DGMLTLDDIRTILPEERYEGSGILKDTFPQDVSIGRMLDLMITVSDNTATNKLVDVVGGF +GPINATIEAAGISRTDLHFGRKMFGGIVPPDGDLWLTPSGMNELLTRIYESSFLSTASAE +HIIDLMLAQQV-KTKLGATVPAG-ILAHKTGENAE-VSHDVGMVLLPGQ-EITLSVFSTV +RPDVQAVANPFLQRIGTAVHDY- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Hydrogenedentes bacterium TaxID=2030809 RepID=A0A3M2EVD8_9BACT +-------LTRLLADSPAKVSVVVCDPRNGWRF-EYGSDEIVRAASVIKLPILVALFRMAE +RGEITLQTRYHLREKDRTGGSGRLRFLPFRHFSLRELAERMIRDSDNTATNAIIRIV-GN +KKLNREFVRMGFKSTRLRHRILASPK------DNPTTAEEISRLLLELENGRLYSDTSRR +ELLAILETCSN-RERLARYLPESLPVPHKTGTLRD-VVHDAGILPTRGG-PLVVVALTTQ +VPR-RRDAARWIARLGGTLY--- +>[subseq from] Beta-lactamase domain-containing protein n=1 Tax=Microbacterium sp. dk485 TaxID=2560021 RepID=A0A4Y9PXP2_9MICO +------------TAAGVDLGVAIEDLSDGRSL-FAGKQDRSTTASTIKMALAVTVMQQVE +AGMLTLDDIRTILPEERYEGSGILKDTFPQDVSIGRMLDLMITVSDNTATNKLVDVVGGF +GPINATIESAGVPRTDLHFGRKMFGGIVPPDGDLWLTPSGMNELLTRIYEAAFLSAASAE +HIIDLMLAQQV-KTKLGATVPAG-ILAHKTGENAE-VSHDVGMVLLPGQ-EITLSVFSTV +RPDVQAVANPFLQRIGTAVHD-- +>[subseq from] Beta-lactamase n=1 Tax=Fusibacter sp. 3D3 TaxID=1048380 RepID=A0A1B6B9D2_9FIRM +--TLSSRIKAINYSFSGTMGVYANDF-KGNTI-EMHADECFETASCIKVPILATLLRRVH +EGKINLKDKISYTQENYVNGSGILRALSMGLLSILDFATLMIIVSDNIATNTLIELL-GI +DTVNETCEMLGLKVTRLHNKID-FEAY---RQLGTTTPREYAKIFELAYEKKLWNAELSD +VFVEILKKQHY-NTMLTKDLTPYISIASKSGSMD-ACRNDGGIFYTPYGG-YAITILTKE +FRYSEHESYQFGPKVSRLILDHy +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. KC345 TaxID=2530371 RepID=A0A4R4QRS8_9ACTN +--DVAQRIEAEFRSAGVTGFLHVTDIDTGREV-AIRAGEPVVLASVFKVPLLVTFHRQAA +GGLLDPAEPVTLRPRDRTAPTGVSGMQDEVRMSLRDLTFLMITVSDNAAADTVLDRV-GR +DAVNATAAALGLHDTIVEVSGRELHEALDPMRTSRSTPRDMTRLLSMIWRDEAAPPDGCA +AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGGRYAVAVFTRS +PLAVLPRADAVIGTAARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Arenibacter sp. AK53 TaxID=1406873 RepID=UPI000A394BAD +-kNLQNGLRELVNNFKGEVGVYVYHTNRNTEA-AINADTIFPTASIVKVPILIGIFDKIN +NGELSLNDPLVYDAKRAYGGAGLMQFYKDSTTDLRTLVSLMITMSDNTTSLWCQELAGGG +ESINALMDNLGLQYTRVNSRTQGRTKDWEKYGWGQTTPREMASLLIKIRNRNLISEASSD +EMYRLLSNSFYTDYSL-SQIPPFIQTAAKQGMVNQ-SRSELVMVNAPTGD-YVFYIATKN +NNDTKNEAWQLQRKISAYLWRYf +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E7JRD2_9BACT +------AMDRLAAEFDGRMGFYVEDINSGVAH-GYCADERFPTASVCKVCVMVELFRQVA +EGACTLGDRHRLAGSISRHGSGTLKWAVDGPLSLRDYCRLMMAISDNVATDALIGLL-GL +EAINATMQSLGYPNLHTGATLTRFHYFADDPANNLAASGEMGRLLGRLCRGEIIDAEASV +GMVEMLGLAAN-RDMIPRYLDPGVDIAHKFGSSGR-IKADVGIVYLPGG-PLVVSAFALA +AA--AADGAAAIAELTRLAV--- +>[subseq from] Serine hydrolase n=1 Tax=Balneolaceae bacterium TaxID=2053516 RepID=A0A5Q4FAE0_9BACT +--SLKMDIERFLESREGTYAVWFEHLQQPELSfSVNPDTIFHAASTMKTAVMAELFRRAE +LGDLSLSDSIRIENRSIVDGSEFQERRAGEMATLGDLNHAMITYSSNIATNLILQIT-GA +AQTTQTMQNLGAGGVEVIRGLYDMKA-FELGLSNRTTARGLGTLFRRIAEGNAISPEMDS +LMISVLKDQFY-RDVIPSLLPESLPVANKTGFIS-GVIHDSAIVWLPNGDSYVLIFLSKE +LP-DNDIGTETGALVSEMIYN-- +>[subseq from] Serine hydrolase n=1 Tax=Komagataeibacter cocois TaxID=1747507 RepID=A0A365YUF8_9PROT +--TLSDDIAKTIQGQPGHFAVYAAMSGQPPQV-CLNCDDFIDAASTMKLFVMDAAYDSFT +KGTLHPQDVIVVHNRSLVGGSFALYAAIGRPVAVSELLRVMIQYSSNLATNLMIERI-GV +PYIRAIVAAQHLDGIRFGRMIEDYDAN-DQGIHNQVSARGLGLFLQKLDHGDIVGPAQSQ +AMIDIMKGQKF-NDMIPPGLPPGTPVAHKTGWVD-GVRNDAGIVFLPDGRHYILVMLTKS +LP-DEAAGIRVLNRISRQVHDSf +>[subseq from] Serine hydrolase n=1 Tax=Emticicia sp. 17J42-9 TaxID=2492393 RepID=A0A4Q5LQJ4_9BACT +--KLKAKLQQAIQGFNGEVGIYVRNLKTNKFV-AINADTVFPTASMIKIPIMIGTFDKIR +QSTLKYEQELVYRDSLKYDDGIVGSLKDSTKIPLSYVMMLICTISDNTGSLWLQALSGGG +KRINAILDSLGFQVTRVNSRTPGREANRSKYGWGQTSPKEMVNLLTMIREGKVISPAYSD +RMYRNLGRQFW-DTEGLSQLPANVKVATKNGAVNR-SRSETALVHAPHGE-YVYSIITKN +QKDEENEGYELLRKVGALLWHHf +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFCSPHIGHO2_02_FULL_39_11 TaxID=1798382 RepID=A0A1F5ZY13_9BACT +-kELLNEIHSLTPPALGTYAVYIYDINSGEEL-GINEQMIFTAASLNKLAILAVLYQEAS +DNQIDLDKIIVPQKEDIQDTGSIRYDPPNTPYSIKTLAKLMIEQSDNTAAHLLGNIVIGL +PQIQKQIEDWDLLQTDMV--------------NNKTSAKDMALLLRKIYKGEITSRPYTL +EMLEFMNKTDF-EERIPTGIPRDVKTYHKTGDEI-GKIHDAAIVELPNK-PYILVVLSSE +IK-DEEKAKQTIAQISRNVYE-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia gamkensis TaxID=352869 RepID=UPI0007A45883 +--------QEIFRTAGVEGWIHAQCVDCGAEA-GTRADEPVVLASVVKVPLVLEFARQVA +AGQVDPADRVRARAADRLGGVGTAGCADDVELSLRDAAYFALTVSDNTAADLLFDRV-GL +DNVRSLLRELGLTATRVVGPPRAVVQALDPRRTTASTPREMVRLLTLIARDQAGAPEACR +WVRDLMRQQVN-WYRLAAAFPPEVGVWAKTGTLP-GVRNEIGVVEYPDRKRYAVAVFTRA +ATQRLPEVDRAIGAAAVAA---- +>[subseq from] Beta-lactamase n=2 Tax=Synechococcus sp. KORDI-100 TaxID=1280380 RepID=A0A076H662_9SYNE +--ALSEKWKQLAAQKDLKTSAYMLILDDGRFA-QLEAERPMPAASSIKTPILLASLELVD +SGDLQWNEPLTLTKELIGGGAGWMAKPVGSRFPTFEVATEMIRVSDNSATNLLIERVGGQ +AAINARFQALGLPATEVNNWLPDLDGT------NTTSARDLSRSIALVDSGETLSPRSRD +LFREVMSTSVT-DTLLPTGLLQGYHVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVQG +PFN-DPRSTNMIRALAKAMA--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. LRa12 TaxID=2563107 RepID=A0A4S2WG49_9ACTN +----AARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVTLHELAA +AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL +DAVNCTAARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLGAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID14478 TaxID=2706073 RepID=UPI0013DBB5A9 +-----DRIRAAFADAGVSGRLHALDIDAGTHL-GVDADDLVCTASVHKLCLLVALHERAS +SGDLVLTQQVDCPPHGRTPPTGVAAMLDAARLSLRDLAYLMMAVSDNAAADLLLAHV-GL +DAVNATTSRLGLDRTQAVHTFGAMLAALDPARTNHSTPRDMTRLLRAVWRDEACPPDHGA +AIRRVMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AQGTLPAADAVIGTAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF65C3A +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGILRALPRLTIKVEELLTIMIIVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGVDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQATNKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Kribbella antibiotica TaxID=190195 RepID=A0A4R4ZSG8_9ACTN +----NARIRAVFDDAGVRGWLHAVALDDAASTvSLDADAVVPMASVYKLPLLAGFCRLVD +DGELDPRAQLTLEPATRTPGPTGLSLLADPVMSLRDLAVMMMTVSDNAAADALLTVV-GL +ERLAELLESFGLQQTWVRRGTAANLLVYEAANASASTPRDMTLLLRRLWAGELLSAAQTD +FAKATMQRQIF-QHRLGSGFPHDIRVAGKTGTFG-ALRHEVGVVTLPAGDAYAVAIFTRT +ARVDQPRADAAIGLAAQLAVN-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-1448 TaxID=1463883 RepID=UPI000B00402F +---TPARIRAVFAEAGVTGWLHALDIDSGAQL-DAGADQLVCTASVHKLCLLVTLHQLAA +TGALDLGEHIECPSAGRTPGPTGLAAMLDPVMSVRDVAYLMMAVSDNAAADLLLGRV-GL +DAVNRTTQRLGLTGTHAVHTFGELFAALDPARTNHSTPRDMTRLLGAVWRDEACTPEHGA +AIRRILGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT +AHATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Subdoligranulum sp. AM23-21AC TaxID=2302961 RepID=A0A372X3B9_9FIRM +-qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERGAGRRAVSASTIKVFILLAALDEVR +RGRLALDTPVAVTAEDILSDTGVFVDGPGM-HPLEELLVWMIVLSDNTATNVLIGLL-GA +ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYAETVLTPELCA +LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD +AP-DIDGDEPLAGRVSKLVFDYy +>[subseq from] serine hydrolase n=1 Tax=Veillonella sp. CHU740 TaxID=2490950 RepID=UPI000F8D66FA +--KARQKLSQISDSIQLAPYESVYIGYHGESV--VKQSKPMRAASMIKVYILGYLFEEVE +AGRISLDETILLQRSDQVGGAGILSGYSGTALTIDELAKLMITVSDNTATNILIHRL-GM +ENINTYIVKHGYADTKLQRNMMDLT-AIEEGRENYTSAKDLGTWFMNLLDGKNMSGASRE +KMLTYLLGQTD-TETFNEALP-NRSIAHKTGELG-GVYHDGGIIFQNN------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Leucobacter komagatae TaxID=55969 RepID=UPI0005AC1FF3 +-dTLTARIAQVAEDAGVFAFAHARDIDTGAEV-GFDSDAPTVTASVFKVPVLVEYVRQVS +AGELDPAQRVRFLPADATLGPTGLSVFSDEAWSLRDVATSMITVSDNAATDIVTGMV-TV +DRVNQTMRELGLPGTQLTGDCARIFEAATPEKTNRTTPREATSLLQQIWTDAAASPEACA +EARRILGLQVW-PHRLSSGFPDDVKISGKTGTLGM-VRNEIGVVEFPDGTRHAIAVFLRG +KTSRNPAADRAIGDIARLLSD-- +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura darangshiensis TaxID=705336 RepID=A0A4V2YXP0_9ACTN +--DVAERIRAEFRSAGVTGFLHVVDMDTGREV-AVAAGEPVVLASVFKVPLLVTFHRQAA +GGVLDPSEQVTLRPDERTAGSTGVSALLDEVMSLRDLTCLMITVSDNAAADAVMDRV-GL +DAVNAAAAALGLRDTVIEVDGRGLHEALDPLRTSRSTPRDMTRLLSMIWRDEAAPPDGCA +AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGARYAVAVFTRS +PTAVLPQADAVIGTAARMAVE-- +>[subseq from] Beta-lactamase n=2 Tax=Chloroflexi TaxID=200795 RepID=A0A2E5HXM0_9CHLR +-eQLNERVAEMIYAFPGIAGCSVKSMVDGNSL-AVNGDVEFPIASTMKIPILLQLLMRDE +NGELDINELVEITPEMIYPGSGVISYLEGPVLSILDIAILMIIVSDNTSTNLCIDYA-GI +EQTNDMLRALGVDNITLRRKMQDTESVIAN-RENVGTPDDCVLLLEHLYNGRP-SKKSAE +RCLSVLRKTKK--SLLNRVIPPDVPLANKPGGMAQ-VRCDAGIVYLSR-YPYAVSIQTSF +AEIGPEEQENYMVELGL------ +>[subseq from] serine hydrolase n=1 Tax=unclassified Clostridium TaxID=2614128 RepID=UPI001122EBD0 +------DIKKFLDSRIGDYSFYFEDLSSGYVY-AMNENVRMPAAGSMKLPIAIALFKEVQ +PGKIDINMKVKVKAEDMVYSTGILHEFSERDYSVKELLTAMLLHSDNTAANKLIDII-GM +DRINEIIRDMRLANTVLNRKSIDERK-SHSEVQNYTSAMDLSKCWRILYNETFVDKENSR +IIIDILKRQQL-KNKLSYYYPERIKIANKTGDIDN-VENDTALMSINKG-SFIITVMSSN +LPN-NVYGQITLARVGKMALD-- +>[subseq from] Beta-lactamase TEM-12 n=1 Tax=Synechococcus sp. MIT S9508 TaxID=1801629 RepID=A0A164B477_9SYNE +---LSERWQTLAAEQDLKVSAFMLVLDDGRYA-QLEPDTALPAASSIKTPILLVTLEELD +AGRLSWNEPLQLSKTVVGGGAGWMAKPLGTRFPTHEVATEMIRVSDNTATNLLIERLGGQ +EALNARFNALGLSATKVNNWLPDLKGT------NSTSARDLARSIALVDTGEALSIRSRD +LFREVMGTSIT-NTLLPRGLLRGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG +PFN-DPRSKELIRKLAAAM---- +>[subseq from] Beta-lactamase class A n=1 Tax=Lacrimispora sphenoides TaxID=29370 RepID=A0A1I0I722_9FIRM +--TLEKRIEAEIMSYDGKMGIYLDDF-HGNVI-AIHADEAFETASTIKTYILACLFDEVE +KGNKSLEDMIEYKEEHVVDGSGVLPDLEPGALRVKDAATLMIIVSDNIATNMMIDYL-GL +ERINQCIKALGCKDTVLHNPIHF-E---QYDRLGTSTPEDYASIFIRLAKGELISPGADE +KMLDILKKQHY-NSMITKDFPPFISVASKSGSMD-ACRNDGGLVFTPYG-PYAIIMFHKE +FSDAAHPATVFGARVSRMILDQf +>[subseq from] Serine hydrolase n=1 Tax=Pseudonocardiales bacterium TaxID=2201155 RepID=A0A2W6D408_9PSEU +---TARTIADTFERAGARGYLHARRVGGPGAL-GLDADEPVVLASVFKIAVALGYARCVA +EGRLDPRARTTIGRGDRVGGIGTAGCADDVQMSWRDVARFMLTMSDNAATDVVLRQV-GL +DAVHRALAELGLHRTRLIGGCAEILAALDPVRTTASTPSEMTSLLDAIWQDRAAAPAACA +EVRAIMAAQIW-PHRLTAGFPDAVRVAAKTGTLP-GIRKQVGVVEYPDGARYAIAVFTRA +REERQPAIDAAIGATARIAVEH- +>[subseq from] Uncharacterized protein n=2 Tax=Ktedonobacter sp. TaxID=1932716 RepID=A0A349M5Z3_9CHLR +----QASIEQELSTLGGHVACVVIRMTDEQELvSINADHVFPAASLAKVPLLIEVARQVE +FGMLCWETRYRVWEGARVASDGVIADLSADLPTVQDLAHLMIAISDNTASNMLLDIV-GM +DAVNATMSNLGLTDTRIERRFIDFEAR-KAGYDNWTTAADMALLYSFFFTE-LLP-GKKK +MLKMLLRQND--YTILPAYWGEKTPFAHKTGGLA-GIIHDAGILYAPTHTPLIIVIMTSE +QV-DEPLTRYTLARVGRIIY--- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522YC23_9BACT +--------------------LHAREIGTGHEV-GLGADEPVVLASTFKVPVALEVFAQAA +EGGLDLSERVRVPVEGRAPGPTGLSVFSHEALSLHDLARSMITVSDNAATDVVCERV-GL +DRVAARLGALGLDEIVIPYDCRGIFAALDPLQTDRGTPRAMTRLLELIWTDTAGPAGACA +QVREVMAQQVW-PHRLTAGFPADVTLAGKTGTLPS-QHNEVGVVGYPDGRSYAVAVYVRS +ARFDQPLLDRAIGEAARIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis decaplanina DSM 44594 TaxID=1284240 RepID=M2ZQH1_9PSEU +--ATSDEIEAVFASAGARGFVHAREIGGGPEV-GVGADDPVVLASVFKIPVAVAFAREVA +AGRLDETERIRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ +ESVDRVLADLGLTRTRLIGCCEDLFAVLDPERTTSSTPREITELLDAIWTDRAGDPAACE +RVRTIMAQQIW-PHRISSGFPAEVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA +ESDRLPAVDSAIGRAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. CH32 TaxID=2530383 RepID=A0A4R4Z4V2_9ACTN +----------VFADAGVRGFLHAREVDGDAET-GLDPDEPVVLASVFKIAVALEYARQAA +AGEISRTERLTVTTADKDGGIGTSGCHDDVSLTLRDLAHFMITMSDNAATDVLLRRV-GL +DRVNGTLAALGLRRTRLIGGCAELFDAVRDPARTTATPREITALLSLVWRDEAGPPEACA +EVRGLMGEQIW-PHRLSAGFPDEVKVSGKTGSLW-GVRNESGVAEYPDGRRYAVAVFVRS +EVERLPHADAVIGRAARLAVEQ- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. E5N91 TaxID=1851996 RepID=UPI000EF57CDC +----AARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVTLHELAA +AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL +DSVNRTAARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLGAVWRDEACPPEYGA +AIRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Sulfobacillus benefaciens TaxID=453960 RepID=A0A2T2X7U7_9FIRM +-----QRIQSVIGRFMGHVGFYAEHMMSHDSL-SYDSQIVMETASVIKIPIMAAAFQYLV +DHNESWETPLRIEPEDIVEGSGILRHLSPGLLPILDVITLMIIVSDNTATNMILRLV-GL +DTVNHFITQHGLAETKLMKRVD---FSIPG-PLGLSTARDMATLLTRLYQRTLVSAQASQ +AMWKILTQQQY-NTIMTRDLPYDVRIGSKSGSLQ-GVRNDVGIVTTPWGD-YVVAILSEK +AKHVDNEALVILPELSRIIFDYf +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3A0AZ97_9CHLR +-----QSIAESLVAASGGFAEVVIALPSGEFIvDINGSEPMESASLYKLGIMVEVFVQRE +VGMLSFDDGVLLEPGYFVEGEDVFGYDIGAVYTVGTLLQAMITQSSNVAATALLATV-GN +ENVNATLASLGITNTQI-RWMPDPSAARADGALNVTTAEDMAWLYTLLLRGEVIAPEVSQ +EMLDLLAAQEV-NDRIPAYLPGGTVVAHKTGNLD-GLVHDAGVIYAPAG-PIIVVVLTED +IDED--VAIDMIAQIALAAYE-- +>[subseq from] serine hydrolase n=1 Tax=Arenibacter sp. JC631 TaxID=2608629 RepID=UPI00123D59B7 +-kNLQNGLRELVNNFKGEVGVYVYHTNRNTEA-AINADTIFPTASIVKVPILIGIFDKIN +NGELSLNDPLVYDAKRAYGGAGLMQFYKDSTTDLRTLVSLMITMSDNTTSLWCQELAGGG +ESINALMDNLGLQYTRVNSRTQGRTKDWEKYGWGQTTPREMASLLIKIRNRNLISEASSD +EMYRLLSNSFYTDYSL-SQIPPFIQTAAKQGMVNQ-SRSELVMVNAPTGD-YVFYIATKN +NNDTKNEAWQLQRKISAYLWRYy +>[subseq from] Beta-lactamase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=A0A381J151_CLOPF +------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE +EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM +DKINETIKEFGMKNTELNRKTAD-ERNFKSDIENYTTAYDLTLAWKKLSEGSFLSKENSQ +MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG +IPNS-VYGTVTLAKSGKMTWD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 62 TaxID=1827599 RepID=A0A3D9M0H1_9ACTN +----ARRITAAFTDAGVTGRLHATDIDTGAAL-GVGSDTPVPTASVHKLCLVATLYRRAH +LGFVDPTRPVDIPAEGRAPGSTGLSVMRDAALSLRDLASLAVAVSDNTAADLLWDAL-GL +DTVNTTMAELGLTHTRAVHTMRELYEALDPTRTNRSTPREITALLAAVWRDEVCPGEYGE +ELRALLGLQAW-THRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA +ASTDLPAADAAIGRAARIAVD-- +>[subseq from] Beta-lactamase n=7 Tax=Clostridium perfringens TaxID=1502 RepID=A0A2X3E4Y9_CLOPF +------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE +EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM +DKINETIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ +MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG +IPNS-VYGTVTLAKSGKMTWD-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A645DLR0_9ZZZZ +------------------------------------------------------------ +-------------------------------------------MSDNVGCDILLRLIGGP +KTVNDFLISKGMKDTQIVYNEEVMQSDWKNQYENYTTMKSSNTLLKDFYQGKIISKESTE +FLLGVLYRTSTGTNKIVEQLPKSAKVAHKTGSSGTGAENDIAIITLPNGKTYALSIFVSD +SMESWETNCKIISNISKAVYD-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. Marseille-P2415 TaxID=1805471 RepID=UPI0009886151 +--TLEKRIEAEIMSYDGKMGIYLDDF-HGNVI-AVHADETFETASTIKTFILACLFDQVE +KGNASLEDMMEYKREHVTDGSGVLAALEPGALRVKDAAAFMIIVSDNIATNMIIDYL-GL +DTVNRCIEKLGCRDTVLYNPIH-FDR---YDRLGTSTPRDYAGIFTRLVRGELISARADH +QMLEIFKKQHY-NSMITKDFPPFISVASKSGSMN-ACRNDGGIVFTPYG-PYVIVMFHKE +FSDAAHPAAVYGARVSRMILDQf +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A523GW54_9BACT +-------------YHDANVAISIIDHSRNVVI-HGDGNRLFHAASTMKVPVMIELYRQEA +AGYLSLDDSLLVENQSIVDGSVYSYDKLGSFMTMRELAYNMITVSSNLATNLLIDRL-SA +DSVQATSERLGTLNAKTVRGVEDLKA-FDQGLSNSMTSRDLAILMEAIRTGIAVSPASDQ +EMVELLLSQFF-NSMISAGVPREAKVAHKTGSITS-VHHDAAIIYPPEDDSFVLVVMTDG +IE-DRIISSELGARIAAAAYK-- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522YPR7_9BACT +--RLQKKIEAAVSGFQGDLGIYIKNLRTGKIV-AVNADTVFPTASIVKVPILIGIMDKIQ +KNELSFDSQLVYKDSLLYEGEDILGSFKADEIALKKVVMLMLTTSDNTASLWLQNYSGTG +TRINEIMDGLGFVSTRVNSRTPGRTNNRTQYGWGQTTPKEMGTLFEKIYRKELFSKEAST +KMLRLLGRNYWDEDEALSQIPPTIEVFSKNGCVD-ASRSEVLLVNAYKN-PYIFCIFTKN +NKTHENEAWTLARKISKLLWEYy +>[subseq from] Uncharacterized protein n=1 Tax=Microbacterium wangchenii TaxID=2541726 RepID=A0A6D1IAD6_9MICO +------------TAAGIDLGVAIEDLSDGRSL-FAGKQDRSTTASTIKMALAVTVMQQVE +DGMLTLDDIRTILPEERYEGSGILKDTFPQDVSIGRMLDLMITVSDNTATNKLVDVVGGF +GPINATIEAAGISRTDLHFGRKMFGGIVPPDGDLWLTPSGMNELLTRIYESSFLSTASAE +HIIDLMLAQQV-KTKLGATVPAG-ILAHKTGENAE-VSHDVGMVLLPGQ-EITLSVFSTV +RPDVQAVANPFLQRIGTAVHD-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=UPI00016BDC15 +------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE +EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM +DKINETIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ +MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG +IPNS-VYGTVTLAKSGKMTWD-- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. MJM2582 TaxID=1427749 RepID=UPI000505EDAB +--AIADEIEAVFAEAGARGFVHAREIGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVA +AGRIDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ +EAVDRVLTDLGLARTRLVGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACE +RVRTIMAQQIW-PHRISSGFPSGVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA +ESDRQPAVDSALGEAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces klenkii TaxID=1420899 RepID=A0A3B0B282_9ACTN +----RGRIRAAFTEAGVTGWLHAADIDSGAQL-DVGADQPVVTASVHKLCVLVALHQQAE +EGLLDLSEQTVCPPPGRTPGPTGLAAMLDEVLSLRDAAYLMMAVSDNTAADLLLRRV-GL +DAVNHTTRRLGLTRTHAVHTFGDFLAVLDPAATNRSTPRDMTRLLGAIWRDEACAPEYAA +SMRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA +SSAVLPPADAVIGTTARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. SGAir0479 TaxID=2567884 RepID=A0A4P8PV55_9NOCA +------RFAELFADAGVRGWVHAVPVRGAAAEtGLDADAPVVMASVYKLPVLVTFCRMVD +SGDLDPREQVTLEPEGRTPPTGISQFLDPVRLSWRDAVRSMMTLSDNAAADEVLRRI-GV +DRVNETMQTLGLHSTRVLGGTAQILQGYDPVLSSATTARDMTTLLSALWRGACASAEQSA +FMRAVTASQVS-TARLRSGFPADVTVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA +ARADLPKADAVIGQAARVAVA-- +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. C10 TaxID=2600577 RepID=A0A5C8K2I1_9ACTN +--------REVFEGAGARGFLHARDVDGDRET-CLDADEPVVLASVFKIAVLLEYALQAA +AGELARTERLTVTAADKDGGIGTSGCADDVSLTLRDLAHFMMTMSDNAATDVLLRRV-GL +DRVHATLARLGLRRTRLIGGCAELFAAVRDPARTTSTPREITTLLARIWRDEAGPAEACA +EVRAVMGRQIW-PHRLASGFGDEVRVSGKTGTLW-GVRNEAGVVEYPDGGRYAVAVFLRT +DKGRDPSADAVIGRAARLAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=A0A127EIB9_CLOPF +------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE +EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM +DKINETIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ +MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG +IPNS-VYGTVTLAKSGKMTWD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNH287 TaxID=1288082 RepID=UPI0009965FD1 +----------------------------SAQV-AIEPDAQLPMGSVYKVPLAVAFCRLAD +AGRLDPRRRITLEPGERVPPTGVSVLHDAVTLSLRDMVVLMMTISDNTSADAVLRAV-GP +GTVDAVCRELGLPDTHIRGGVVSTFHVYDPAYEASTTPSDMTRLLRAIWTGEAASGDRCA +FLREVMRRQPW-AHRLGSGFPDDVTVYGKTGTFG-AMRHEAGVVELADGSAYTAVVFTQA +ARSDLPRADAVIGAAARAAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium psychroaquaticum TaxID=561061 RepID=A0A1X7J294_9SPHI +-kKLEERLKKETENFQGDIGIYVQHFKKNTTV-NILADTIFPTASIVKVPILVGVFNKIN +EGSLTLRQPFRYDAKRVYGGSGLMQFYKDSATELSIMISLMLTYSDNVTSIWNQELAGGG +VEINRIMDQLGLVNTKVNSRTTGREQLWRKYGWGQTTPQEIASLMHLIRSGKVFNPQLSD +KMYRYLKNQFY-NERSLSQIPAEIATASKTGSVDD-ARGEVVYVHAPSGD-YVFSVLTKN +NKTDENEAEKITRKIASIIWNYy +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. TLI_146 TaxID=1938858 RepID=UPI000C7095B3 +---AAARIREAFDQAGVTGRLHALDIDSGAEI-GSGGDQAVVTASVHKLCVLVALHEQAA +AGRLDLTEQLEVPLEGRELGPTGMAAMLDPVMSLRDAAYLMMAVSDNTAAELLLGRI-GL +DAVNATTARLGLAHTHAVHTFRELLAALDPARTNRSTPRDMTRLLSAVWRDEACTPEHGA +AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVIEYPDGGRYAVAVFTRA +ASATLPPADAVIGTTARIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces niger TaxID=66373 RepID=UPI00069A906E +------TIREMFADAGVRGWLHVAELHREARV-TVDPDEPVPMGSVYKVPLMVAFCRLAD +AGELDPALRVTLEPSHRVAPTGISILQDAVSMSLRDLVVLMMTISDNTAADAVLRAV-GS +TVVDGVCRELGLPDTRILGGVAGTWAVYDPVSKASTTPSDMARLLRAIWTGAAASAERCA +FMRDVMGRQPW-RHRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELADGSAYTAVVFTQA +ARADLPRADAVIGAAARTAVE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CB02056 TaxID=1703924 RepID=UPI000A456F28 +--AARTRIAAAFADAGVTGRLHARDLDTGAEI-GLGADTAVSTASVHKLCLLVTLYREAA +AGRIDLTRQVDVPAAGRTPGSTGLGAMLDDALSLRDLAYLTAAVSDNTAADTLWDRI-GL +DTVNRTMADLGLTRTVAVHKLRDLIAVLDPAFTNHSTPRDMTTLLAALWHGDACPGDHGA +ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA +AATTLPAADAAIGTAARLAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Antarcticibacterium sp. PAMC 28998 TaxID=2585771 RepID=A0A5B8YGN6_9FLAO +--TLEKELREIVKDFKGLAGVYVYNLKTRQEA-GIHADSVFPTASVVKVPILAGLFNKIE +KGELSLFDTLIYNKERVYGGSGLMQFFKDSTTDLRSAAALMITYSDNVTSIWSQELAGGG +EEINNLMEGLGLEHTRVNSRTPGREDLWKKYGWGQTTPREMAGLLIKMRNRELVSEAASD +EMYRMMTNSFY-TDYALSQIPPYVQTAAKQGMVNQ-SRSELVMVNAPGGD-YVFYIATKN +NEDTENEAWVLQRKISAFLWNYf +>[subseq from] serine hydrolase n=1 Tax=Vulcanococcus limneticus TaxID=2170428 RepID=UPI000B9994AB +-----KKWAALAAVHDLKASAYLLVLDDGRFA-QLQSELPLPAASSIKTPILLAAMEDLD +AGRLRWDQPLTMTKEVVGAGAGWMAKPVGTRFPFHEAATEMIRVSDNTATNLLIKRLGGK +TALNTRFQALGLPGTVINNWLPDLEGT------NTTSAHDLARSIALVDTGEKLSPRARD +LFRQVMGSSRT-NTLIPLGLLQGVTVLNKTGDIGI-AYADGGLIELPNGQRAVAAFMVKG +PFND-PRSTDLIRAMAAEVA--- +>[subseq from] serine hydrolase n=1 Tax=Lacrimispora amygdalina TaxID=253257 RepID=UPI000BE2B6EC +--TLEKRIKAEIMSYDGRMGVYLNDFH-GNEI-ALGQDEKYETASTIKPFILACLFDEVE +KGNKSLEDLIKYKEEHVVDGSGVLAALEPGALRVKDAAVFMIIVSDNVATNMMIDYL-GL +DTINRCIKELGCSDTVLYNPIHFDQY----RRLGTTTPRDYGSIFTRLVKGELISPEADA +AMLEILKKQHY-NSMITKDFPPVITVASKSGSMD-ACRNDGGIVFTPYG-PYVIVMFHKE +FSYPAHPATVFGARVSRMVLDQf +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. TLI_146 TaxID=1938858 RepID=A0A2N3W5K4_9ACTN +---AAARIREAFDQAGVTGRLHALDIDSGAEI-GSGGDQAVVTASVHKLCVLVALHEQAA +AGRLDLTEQLEVPLEGRELGPTGMAAMLDPVMSLRDAAYLMMAVSDNTAAELLLGRI-GL +DAVNATTARLGLAHTHAVHTFRELLAALDPARTNRSTPRDMTRLLSAVWRDEACTPEHGA +AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVIEYPDGGRYAVAVFTRA +ASATLPPADAVIGTTARIAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Pedobacter sp. TaxID=1411316 RepID=A0A520E5E6_9SPHI +-qKLQQKLNDLVKGFNGDVGIYVKNLKTGKIA-SVNADTIFPTASMIKVPITCGVFNKIE +KGELDYHASLTYCDSLLYAGEDILGSFKDSEIALSKVLMLMITTSDNTASLWSQLLAGTG +TAINEVMANNGLKDTRVNSRTPGRRENQKQFGWGQTTPKEMATLLTLIRDGKMISPAASE +RIYRNLIRIYW-DTEALSQIPPTVQVASKSGAVD-AARSEVLLVNAPHGD-YVFCITTKN +QKNYTNEGWTMIRNLSNLLWNYy +>[subseq from] Beta-lactamase class A n=1 Tax=Ohtaekwangia koreensis TaxID=688867 RepID=A0A1T5JKG3_9BACT +--VLQQKLQELVKGFKGDVGIYVRNLKTGKIA-AIDADTLFPTASMIKVPITVGMFDKIE +KQEIRYDSMLTYKDSLLYEGEDLLGSFKDGEIALKAVLMLMITTSDNTASLWCQLMAGKG +TTINAWLDNNGFKQTRVNSRTPGREMNRTKYGWGQTTPKEMSELVVRIREGKVISPRVSE +RIYRNLIRIYW-DTEALSQIPPYVQVASKQGAVNQ-SRSEVALVNAPHGD-YVFCVITKN +QKDENNEGWVLIRKVSSLLWNYf +>[subseq from] serine hydrolase n=1 Tax=Bordetella sp. J329 TaxID=1977852 RepID=UPI000FD79110 +--RLAQGLAPILTSTQARVTMAVHTLDGTPLF-EREARTAMPSASLIKVPILLLLLEQVA +AGRWPLDHMLSLEHTERVGGTGILNQLPSVRLQLEELGRLMIVLSDNVATNALIDWL-GL +DSVTQWCQRAGLPQTRLERRMMDAQAR-AAGRDNWTSAADACAALLWLLRSSSLPAPLRQ +LGLQMLADQRE-QSHFGAALPAHAKLANKTGQLH-GLRHDAGILSAGG-QSVVLAVLADG +FTDP------------------- +>[subseq from] Beta-lactamase n=2 Tax=Lactobacillus perolens TaxID=100468 RepID=A0A0R1N785_9LACO +--EVQAAVNQTMGQIPGDNSVFVSASDELHLKhFVQNNRPQRAASIIKIFIMVTAFAKAK +NGDLNLADTYTVTGADKVSGTGDMQNMPDGTLSYRQVMDHMMEKSDNMAANVMIDYLGGL +DVVNQEIKKLGFPDTVLERKMMDTD-ALAAGKDNMTSVQDLGDALTLINNGKLISKEADN +QMMAIMKNNQN-HEKLPAKITNATAIYNKTGEFQYGVENDAAIIQGDRH--IFVAVVMSQ +NGHSG------------------ +>[subseq from] serine hydrolase n=1 Tax=Streptomyces tendae TaxID=1932 RepID=UPI00133106C9 +--ATAARLDAAFADAGVTGWLHAVDIDSGAQI-GAGADQPVCTASVHKLCVLVTLHELAA +AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL +DAVNRTAARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLGAVWRDEACPAEYGA +AVRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536K880_9CHLR +---------ALRRPFSGRLGFWALNLRTGELL-EHNAEEIFPSASTIKLFVLRELYRQAE +AGRLDLDRSVVMQHKDVTTGSGVIKDLTTGLLSLRDAATLMITVSDNTATNLLVRLL-GT +RAINQGARQAGYAGTRCAGRIFKGNRM-----RSLSSPRDLGVFMANVALGRELSRAASQ +AMLDTLKREQY-ANIVGRLIPTRWLLASKSGSLV-GVRNDAAYVKGPGV-RYAIALMSSD +CEDEDNEANLVLARLAADIHAHf +>[subseq from] serine hydrolase n=1 Tax=unclassified Microbacterium TaxID=2609290 RepID=UPI00049326BF +-----PDIAALFTEAGATGFLHAREIGGGPEV-SVDADEPVVLASVFKILVLTAYVRAVA +AGELDPTERTTVTARYRIGGVGTAGFSDDVEASWRDLAQNMMTMSDNAATDVVYHRL-GS +DAVNRVISDLGLRHTRLVGCCEDLFAAVHPAKTSHSTPRDVTTLLYALWTDTAATAEACR +QARDIMAQQIW-PHRLSSGFPPGVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA +ASERQPLVDASIGR--------- +>[subseq from] Serine hydrolase n=1 Tax=Cupriavidus metallidurans TaxID=119219 RepID=A0A2L0X380_9BURK +--RVETALAPLLAGTQARVAISLR-LADGKVVlEREAERVQPSASIIKLPILFTLLEQVA +QGHLQLEQRFSLDGLERVGGTGILNQLPSVQLTLAELARLMIVLSDNLATNALIELL-GF +EGVNDWCDRAGLGQTRLQRRMMDAAAR-AAGLDNFTSASDAAASLCWLLRDGSLPAPLRD +FALGLLADQRE-RAHFGAALPAGAMLANKTGQLP-GLRHDAGILTVGAY-SVVLAVLADG +FTDAGGDGAQWLAEAARIVA--- +>[subseq from] Serine hydrolase n=1 Tax=Lacrimispora algidixylanolytica TaxID=94868 RepID=A0A419T6E8_9FIRM +--TLEKRIEAEIKSYDGIMGIYLDDL-HGTTI-EIKAEETFETASAIKTLILACLFEEVE +KGTVSLEDMIEYKKEHSVDGSGVLLAEPGARLRVKDAATFMIIVSDNIATNMLIDYL-GL +ATINRCIKGLGCMDTVLHNPIHF-D---QYDRLGTSTPRDYASIFIRLTKGELISPKADQ +MMLEILKKQHY-NSMITKDFPPYFTVASKSGSMD-GCRNDGGIVFTPYG-PYVIVMFHKE +FSDAAHPATLFGARVSRMILDQy +>[subseq from] Beta-lactamase class A n=2 Tax=Arachidicoccus rhizosphaerae TaxID=551991 RepID=A0A1H4D2N8_9BACT +-kALQEKLSVLLDQFHGTAGIYVENLRTGKFA-GVHADSIFPTASIIKVPILAGVFSQIK +AGKLSYNQELTYDTSRTRGGSGLMQFFKDSSTSLDILLSLMISYSDNVAALWCQQLAGGG +TQINQLLNDYGFKSTRVNSRTPGREEAYKEFGWGQTTPREMATLLKLIRQQKIVDPASSD +CMYRQMSHIFY-DGYALSQIPPYIQTASKQGMVDD-SRSELVMVNAPHGD-YVFYIATKN +NQDQRWEKDALARAVSSLLWHY- +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A2A7B4T6_9FIRM +--TLEKRIAAELYSYQGKMSVFVDDL-QGRTV-EIGADEAFETASTIKAFILAALYLQVS +RGKASLDERITYEESQFVDGSGMLRAGVGAALKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFAHTVLHNPLH-FDR---YRDLGTTTPRDYAALFAQVAKGTLVSKEASA +EMLAIFRQQHY-NTMLTHDFPERIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] Beta-lactamase n=2 Tax=Lactobacillus bifermentans TaxID=1607 RepID=A0A0R1GKJ0_9LACO +--KVRQTVQQTVGHLSGDTSVYIAPTRGTGAV-SIRPQ-PQRSASSIKLFILTAAYAH-- +--HLDLQATHTLTAAEQVGGTGVLQTMAAGTLTYQEILTKMITDSDNTATNIIIDQLGGV +TKVNQEIQALGATQTTLRRKMLDTQ-ALANGKDNTTTAKDMGVLLTKLYNHQCLGTTDDN +AILSILAQTKN-HEKLPAQLPTGTTIYNKTGEYDYGVQNDAALIKNNKGA-FVAVVLSQN +GQQA--Q---------------- +>[subseq from] Beta-lactamase n=1 Tax=Flavihumibacter sp. ZG627 TaxID=1463156 RepID=A0A0C1IAC6_9BACT +-rKLQKAIESLVEGFKGTVGIYVKHLPSGRSA-QINADTLFPTASMVKIPIMIGIMDKIH +KNELQYHQPLVYNDSLLYAGEDILGSFKSGEIQLAKVLMLMMTTSDNTASLWLQSMAGTG +TRINQLLDSMGYSATRVNSRTEGRRGHWEQYGWGQTSPREMVRLLEQIYQRKMINDTLSE +RMLRLMGRNYW-DEEAISMIPPEIFVASKNGAVD-ASRSITMLVMAPHG-PYLFSVITKN +QPDT------------------- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=R4T315_9PSEU +--TISDEIEAVFAKAGARGFVHAREIGDGPEV-DVGADDPVVLASVFKIPVAVAFAREVA +AGRIDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ +EAVDRVLADLGLARTRLIGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACE +RVRTIMTQQIW-PHRISSGFPADVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA +GSDRLPAVDSAIGEAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. ERV7 TaxID=1322334 RepID=A0A197SKR3_9ACTN +----LARIREAFDEAGVTGWLHALDIDSGAET-GVGGDHAVVTASVHKLCVLVALHEEAA +AGRVDLTEQIEVPLEERELPTGVAAMLDPVRMSLRDAAYLMMAVSDNTAAELLLARV-GL +DAVNATTARLGLTHTYAVHTFRELLAALDPARTNRSTPRDMTRLLAAVWRDEACAPEHGA +AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVIEYPDGGRYAVAVFTRA +AAATLPPADAVIGTTARIAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3A0ADA2_9CHLR +--ALDRQLAGIRERFSGTLSLAASNLKTDEAV-TLDAGMLLPTASTIKVCILAEVFHQRE +EGRLRLDERIEMQARDQVGGSGVLWRLNSGLPTLYDLCMLMIIKSDNTATNMLTDRVGGV +GIINRRMRDYGLAETSYHSRVDF--EAIGNDVRAESTPYDLMRLMAMLARGEVVSPQASR +EMLAIMQRQQY-LDQFPRYLNSTMRVQNKTGFFP-GTGVDIGVVNLPEGVDIAYAVFAHA +SRDHTVA---------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Hydrotalea sandarakina TaxID=1004304 RepID=A0A2W7RQ57_9BACT +-kKLTAELQSYLKKFHGQAGIYVYSFQQHKQV-AIAADTVFPTASMVKVPILIALMDKIK +AGELQYHQTFTYYDSLAYPGVDILASFKNGEIELSKLILLMLSLSDNTASLWLQAIAGGG +TRINNLMDSLGFTQTRVNSRTPGREAIRLQYGWGQTTPYEMAMILKRIASGTLLGQPYDD +KMLRLLSRNYW-DEEALSQIPANVFVASKNGAVD-ASRSEVLYVNGKKG-SYVFCLCTNH +NTETNNEAWALSRNISKLLWEYy +>[subseq from] serine hydrolase n=1 Tax=Microbacterium sp. Root61 TaxID=1736570 RepID=UPI0009EAAA2C +--------------VPVRGLIHAVDIDTGHEI-GVGSDESVVSASVFKVPVLVELCRQYS +SGRIDPRARIALGADERRTGSTGISVMLDELLSVRDMSLLMMSVSDNRATDVITDLV-GL +DNVNATMREFGFDRTVVDYDCDMLFAATTPEETDRTTPRQIAELLSAIWRDELLDADAAA +EVRRVMGLQAW-GHRLTAGFSPAVRVSGKTGTLFY-VRNEVGVVEFPTGERFAVAVFLQE +PTPRNPDADRVIGTAARLAVDY- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. ERV7 TaxID=1322334 RepID=UPI000B22942C +----LARIREAFDEAGVTGWLHALDIDSGAET-GVGGDHAVVTASVHKLCVLVALHEEAA +AGRVDLTEQIEVPLEERELPTGVAAMLDPVRMSLRDAAYLMMAVSDNTAAELLLARV-GL +DAVNATTARLGLTHTYAVHTFRELLAALDPARTNRSTPRDMTRLLAAVWRDEACAPEHGA +AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVIEYPDGGRYAVAVFTRA +AAATLPPADAVIGTTARIAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. TaxID=1831 RepID=A0A520FI07_RHOSO +--------------------------DDGGDI-AVGADDLVVLASVYKLPLLVSLCRAFD +SGSVSPTATVRVNPADCTPPTGVSKFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL +ESIERMLSELGLTGTRVIGGTADAHRAYDPSYASATTPRDMTTLLDAIWTGSAVPEPQGE +FIRQVMAAQVW-QHRIRSGFPSDVDVAGKTGTIG-AIRNEVAVVTFPGEIPVAVSVFTRA +ARADLPVVDAAIGHAARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Nocardia panacis TaxID=2340916 RepID=A0A3A4JXW9_9NOCA +---VPERLTEIFRAVGATGYVHAREVDGPGEI-GLGADHPVVLASVFKIPVVLTFARQVE +AGELDPTERTTITARDRIGGIGTAGCADDVEMSWRDLALFTLTMSDNAATDVLLRRV-GI +DAVRAVLAELGLERTRLIGGCEDLFAVCDPARTTASTPRELTTLLTAIWTDTAGPAEACA +RVRTIMGQQIW-PHRIASGFGDEVSIGAKTGTLPF-IRNEAGVITHRDGKCYAVAIFTVA +DSMRAPAVDAAMGKAARLVVD-- +>[subseq from] Beta-lactamase n=1 Tax=Lacrimispora sphenoides TaxID=29370 RepID=A0A381JN56_9FIRM +--TLEKRIEAEIMSYDGKMGIYLDDF-HGNVI-AIHADEVFETASTIKTYILACLFDEVE +KGNKNLEDMIEYKEEHVVDGSGVLPDLEPGALRVKDAATIMIIVSDNIATNMMIDYL-GL +ERINQCIKALGCKDTVLHNPIHF-E---QYDRLGTSTPEDYASIFIRLAKGELISPGADE +KMLDILKKQHY-NSMITKDFPPFISVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE +FSDAAHPATVFGARVSRMILDQf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL F-5650 TaxID=1463868 RepID=UPI00068E0E3B +---------------------HAVDIDSGAQV-GTRAEQPVCTASVHKLCLLVTLHELAA +AGTLDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Putative beta-lactamase n=1 Tax=Synechococcus sp. (strain WH7805) TaxID=59931 RepID=A4CVR1_SYNPV +---LSDRWNQLAASEDLTVSAFMLVLDDGRYA-QLAPDTALPAASSIKTPILLVTLEEID +DDKLSWNEPLTLTKEVVGGGAGWMASPLGSRFPTHEVATEMIRVSDNTATNLLIDRLGGK +DALNARFIALGMSATVVNNWLPDLEGT------NTTSARDLARSIALVDTGKALSIRSRD +LFREVMGTSVT-NTLLPRGLLRGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG +PFND-PRSTELIRKLAAAM---- +>[subseq from] Beta-lactamase class A n=1 Tax=Kushneria indalinina DSM 14324 TaxID=1122140 RepID=A0A3D9DXH3_9GAMM +------------------------------------------------------------ +----------------------------------------------------------GD +ERVAALARTLDVDREALNTDMTTAFDRYYDTRVNSATLKGYADLLTALVRGELINEEHRE +LLFDNLKIDRYDGYRLEGGLPQDVSFIQKTGTQHQ-RACHMGVIRPDEPNAIVIAACIED +MD-EGAPAEALFKQIGEAITE-- +>[subseq from] Beta-lactamase class A n=2 Tax=unclassified Cupriavidus TaxID=2640874 RepID=L2EKL5_9BURK +--RVETALAPLLAGTQARVAISLR-LADGKVVlEREAERVQPSASIIKLPILFTLLEQVA +QGHLQLEQRFSLDGLERVGGTGILSQLPSVQLTLAELARLMIVLSDNLATNALIELL-GF +EGVNDWCNRAGLGQTRLQRRMMDAAAR-AAGLDNFTSASDAAASLCWLLRDGSLPAPLRD +FALGLLADQRE-RAHFGAALPAGAMLANKTGQLP-GLRHDAGILTVGAY-SVVLAVLADG +FTDAGGDGAQWLAEAARIVA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Thermoflavifilum aggregans TaxID=454188 RepID=A0A2M9CVU9_9BACT +-rKLQRKLEALVKPFQGTVGIYVHKLGTNREA-AINADSLFPTASMIKVAIQAVIFQRIA +DSQLQYHQNLLYRDSLYYPGVDILGMAKDSTIELSKVVMLMITESDNTAALWLQSLAGGG +TAINQWLADHGYQYYRVNSRTPGREAAYRQYGWGQTTPREMARFLVQLRKGEIISPAASE +RMYRNLCHIYW-DDVALSQIPPYVQAASKQGAVDD-SRSEVVLVNAPHGD-YVFCVDTKN +IATHSNAAWELIRQVSALLWHYf +>[subseq from] Uncharacterized protein n=2 Tax=Gemmatimonadetes TaxID=142182 RepID=A0A351FLB3_9BACT +-eHLHSELSSIAERYEGVAGIHVLDLSSGDRF-AVRDDFIFPQASAIKIPILLELFRRAE +SDPGLLSKRIEMTEEVRTGGSGVLGVLTDGGLSLEDYAIYMILHSDNTATNILIDEL-GM +GPINALSASLGAPNTLLQRKMIQPEES-ARGNENLSTPRDAAEIMKRIANCELMSEIACA +RVIEILSIPKGG--PIRRPVPNAIPIAFKPGGIT-GVATVWAIVDVPDR-PYVITVMSNY +GG----DGGAVIEAAQKAAYSYf +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A358IEP4_9BACT +-eHLHSELSSIAERYEGVAGIHVLDLSSGDRF-AVRDDFIFPQASAIKIPILLELFRRAE +SDPGLLSKRIEMTEEVRTGGSGVLGVLTDGGLSLEDYAIYMILHSDNTATNILIDEL-GM +GPINALSASLGAPNTLLQRKMIQPEES-ARGNENLSTPRDAAEIMKRIANCELMSEIACA +RVIEILSIPKGG--PIRRPVPNAIPIAFKPGGIT-GVATVWAIVDVPDR-PYVITVMSNY +GG----DGGAVIEAAQKAAYSYf +>[subseq from] Uncharacterized protein n=2 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A3D3QJL7_9BACT +-eHLHSELSSIAERYEGVAGIHVLDLSSGDRF-AVRDDFIFPQASAIKIPILLELFRRAE +SDPGLLSKRIEMTEEVRTGGSGVLGVLTDGGLSLEDYAIYMILHSDNTATNILIDEL-GM +GPINALSASLGAPNTLLQRKMIQPEES-ARGNENLSTPRDAAEIMKRIANCELMSEIACA +RVIEILSIPKGG--PIRRPVPNAIPIAFKPGGIT-GVATVWAIVDVPDR-PYVITVMSNY +GG----DGGAVIEAAQKAAYSYf +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CB00013 TaxID=1703945 RepID=UPI00094032C5 +--AIADEIEAVFAKAGARGFVHAREIGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVA +AGRIDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAQFMLTMSDNAATDVVYHRV-GQ +EAVDRVLTDLGLARTRLVGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACE +RVRTIMAQQIW-PHRISSGFPAGVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA +ESDRQPAVDSSLGEAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7NZP1_9BACT +---LRLQIEKIVQGFAGKAWIAARNLGTGKSF-SLNSSERVRTASTIKLPILVALHAEVQ +AGRLRWEDCLTLAKKHRAQGAGVLMELEDGHLTLREASRLMVVVSDNSATNLVLEKI-GI +DTVNTWMDRFNLPKTRALAWIGGGAID--GSTHGVTTPAEMVDLLDRLNRGQIISPEDSA +QILALLGRQQY-KDGIGRNLR-GARVANKPGALDR-LRSDVGIITVGKE-KFALAITLDD +MP--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A413LQ89_9CLOT +---IEKRIEAELMSYDGTMGIYADDLH-GNII-AIGADEAFETASTIKTYILACLFDQVE +KGKASLEDMVEYKEEHTVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL +DTINACIRGLDCRDTVLYNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPESDA +KMLEIFKKQHY-NSMITKDFPAVVTVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNRK +F---------------------- +>[subseq from] serine hydrolase n=1 Tax=Xanthomonas citri TaxID=346 RepID=UPI001243DFB1 +---------ELVAHCEGRVGLVIETCEGR--I-EINHNDKFSAASLIKIPILIEGFRQYE +KGLLDLHEYLLALPSNRVGGAGVIQALSADLLKIIDLMALMIIVSDNSATNLVIDRV-GM +TEINECIKALNLQNTELNRKMMDFEAK-KNGLDNFTTANDMLTCLKVIDQHRFLSKESSD +KAFSILEKQQFKNKLAETIDSEAVQVANKTGELP-GVEHDCAIFKYGGK-TIYAAVLIDQ +LSRQEEGRLTLI-QIGK------ +>[subseq from] Uncharacterized protein n=2 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A3D2UF86_9BACT +--HLLSELSSIAERYEGVAGLHVLDLSSGDRF-AVRDELIFPQASAIKIPILLELFRRAE +SDPGLLSKRIEMTEEVRTGGSGVLGVLTDGGLSLEDYAIYMILHSDNTATNVLIDEL-GM +GAINALSASLGAPNTLLQRKMIQPEES-ARGNENLSTPRDAAEIMQRIANCELMSEMACA +RVIEILSIPKGG--PIRRPVPNAIPIAFKPGGIT-GVATVWAIVNVPDR-PYVITVMSNY +GG----DGGAVIEAAQKAAYSYf +>[subseq from] Serine hydrolase n=1 Tax=Spirosoma sp. 48-14 TaxID=1895854 RepID=A0A1Q3WZU2_9BACT +--RLEQKLQSALAGFRGNAGVYVYHIRTGKRV-SINADTLFPTASMIKIPIQCGLFDKIH +KGELSYNQELVYKDSLHYDDGIVGSLKDGARITLSKVVMLMETISDNTGSLWCQALAGGG +TAINTWLETNGFHQTRVNSRTPGREANRGQYGWGQTTPRDMANLLLYIRQGKAVSPDASD +EMYRNLGRQFWDGDGL-SQLPPDVKVATKNGAVNQ-SRSEVVLVHAPHGD-YVYCVMTKN +QQERTNEGYALLRTVGSIVWHHf +>[subseq from] Beta-lactamase class A n=2 Tax=Alkaliphilus TaxID=114627 RepID=A0A1G5IV08_9CLOT +-kELQDIIQKHINEIEGTAAIYVKDTETNEVI-TINSQERFHAASTIKIPILWEALRQVE +KGSIKLDDKILLKDVDKVGGCGVLFLHNGLQLTLEDLLHLMIDISDNTATNMVIDFI-GK +DNVNKALEELGMVDTFLARKLMVV---IPG-VYSYTCAKDIGRILEAFITHEGLHKEYAE +KGLAILEAQQL-NNRLSQEL---------------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus koreensis TaxID=2054903 RepID=UPI001056F6B4 +---------------GGRVAFCVHELGTGMIR-AQRADEVVPTASTYKLPLLLHIALLVE +EGALSWAQPFTLEDRHKSWGSGVLRDSVGLTFPLRDLCHLMTALSDNTATDLLLDTL-GL +DGVNRRLAGLGFEQTRLLPQHAAPGAGRPPLAVGVTTPAEMARLLRGIVLHELCSSASSS +VILGMLGAQHD-RSMIPRFLQPDWIYSGKTGSNED-LRADVGIVTDPQGRSFVLALYCQH +PT--------------------- +>[subseq from] serine hydrolase n=1 Tax=Halorubrum aethiopicum TaxID=1758255 RepID=UPI0008303CBB +--DLAEAIDVIADRFDGRLGVLLGLSRGPDVLhRRNADEAFVAASTIKLPVLYALYEEYD +GRLDALAEPRPIAAENRVGGSGIFHLLDDPTPSLEDLARATIAISDNAATNQLIDEL-GA +ERIEAAASRLGMADTRLRRKMMATLEQPDGEPANVTTPADCARFFADIVHESTLSPAAYD +RLRVPLDEQKD-ASLFARYLPYGTPIAHKTGGLPT-AALDAGVVRADDGPPLVFTAFATQ +AEN-GGDAGDAVAAVGDAAFERf +>[subseq from] Beta-lactamase n=2 Tax=Rhodococcus opacus TaxID=37919 RepID=K8XS33_RHOOP +-------------------------IDDGGDI-AVGADDLVVLASVYKLPLLVALCRAFE +SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL +ESVERALSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGSQGE +FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA +ARTDLPVVDAAIGHAARIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Rhodospirillaceae bacterium SYSU D60006 TaxID=2268029 RepID=UPI000E65750B +-dTLTARINEVAEEAGVFAFAHARDIDTGVEV-GFNSDAPTVTASVFKVPVLVEYVRQVA +AGELDPAKRIRVSPAEATLGPTGLSVFSDDAWSLRDIATSMITVSDNAATDIVTGLV-TV +DRVNATMRELGLPGTQLTGDCALIFEAATPEKTNRTTPREAASLLQQIWTDAAAPAEACA +EARRILGLQVW-PHRLSSGFPDDVKISGKTGTIGM-VRNEIGVVEFPGGKRHAIAVFLRG +KTSRNPAADRAIGDIARLLSD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Synechococcus sp. Ace-Pa TaxID=2572902 RepID=A0A560LMM5_9SYNE +---LSQRWKALAAQKDLKAGAFLLVLDDGRFA-QLDSELPLPAASSIKTPILLAGLEDLD +AGKLRWNEPLPLTKEVVGGGAGWMASRPGTRFPFYEAATEMIRVSDNSATNLLIKRLGGK +LALNARFQALGLGATVVNNWLPDLEGT------NTTSPHDLARSIALVDTGEKLSPRGRD +HFRTIMGTSRT-NTLLPLGLLEGVTVLNKTGDIGI-AYSDAGLIELPNGQRAVAAFMVKG +PFND-PRSADLIRAMAAAAS--- +>[subseq from] Uncharacterized protein n=1 Tax=Virgibacillus massiliensis TaxID=1462526 RepID=A0A024Q8C3_9BACI +-------------------KYFSIYIETPDGIiAINEDKQMTAASLVKLPILLEGFRQLE +NNHLLEDKLVYIDKDEMVGGAGVINYVSKSHYSYKNLMELMIIVSDNTAANLLLKLF-GM +AAINQFIKSIDCEQTLISRKFMDVEAS-ENGKENYTSAKDMIKLFKLVSKNHHLTDSSRR +MILKILENQQF-THKLPSYLDKSIRFFHKTGEMP-GVSHDAGIIKYETK-TIHVAILSEG +VA-HNTVSERIIADIGHLLS--- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 04169 TaxID=2203197 RepID=A0A429C8Q1_9PSEU +--TISDEIEAVFAKAGARGFVHAREIGDGPEV-DVGADDPVVLASVFKIPVAVAFAREVA +AGRIDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ +EAVDRVLADLGLARTRLIGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACE +RVRTIMAQQIW-PHRISSGFPADVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA +GSDRLPAVDSAIGEAARLAVDH- +>[subseq from] Uncharacterized protein n=1 Tax=Subdoligranulum sp. 4_3_54A2FAA TaxID=665956 RepID=G9RYL9_9FIRM +-qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERGAGRRAVSASTIKVFILLAALDEVR +RGRLALDTPVAVAAEDILPDTGVFVDGP--GHPLEELLVWMIVLSDNTATNVLIGLL-GA +ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYDETVLTPELCA +LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD +AP-DIDGDEPLAGRVSKLVFDYy +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus wratislaviensis TaxID=44752 RepID=A0A402CDX0_9NOCA +---------------------------DAGDI-AVGADDLVVLASVYKLPLLVALCRAFE +SGELSPTATVRVNPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL +ESVERVLSDLGLTDTRIIGGTADTHRAYDPSYASATTPREMTSLLDAIWTGRAVPGAQGE +FVRQVMSAQIW-QHRIRSGFPSGVDVAGKTGTIG-AIRNEVAVVTFPGEIPVAVAVFTRA +ARTDLPVVDAAIGHVARIAVT-- +>[subseq from] Uncharacterized protein n=2 Tax=Candidatus Shapirobacteria TaxID=1752721 RepID=A0A2M8L7Z1_9BACT +-----DQIKAVTTPLLGVYGVYVENLVSGHQY-GLFQKQTFPMASLVKLPVILTLYQEAE +ADRLNLEDEYPLREADKLGGAGILQSQPAGSYTYRQLAQLMGHYSDNTAYNVALKVL-GL +AKVQRTIEQLGMASTALADFE--------------TTPADMGLFFRRLYAGKLVNNLHQQ +EIFEFLTATVF-EDRIPAGVPEGVRVVHKVGTEI-GNFADAGIVMAP--QPFVLVIITQD +ARES--EALTALPEISRLVWE-- +>[subseq from] Serine hydrolase n=1 Tax=Niastella vici TaxID=1703345 RepID=A0A1V9GA25_9BACT +-hRLQKQLSDLVKDLHGDIGVYVKNLRTGKSA-MVNADSIFPTASMVKVTILIGIQDKIE +KGQLEYHQPLEYKDSLFYAGEDILGSFKNGEIGLNKVMMLMLTTSDNTASLWLQSLAGTG +TRINEILDSLGLVHTRVNSRTPGREANRQQYGWAQTTPREMGTLMEKIYRGEVISKSSSE +KMIRLLGRNYN-DEQAIAEIPPYIFVASKNGCVN-ASRSEILLVMAPHG-PYIFSVQTKN +LQGNSNEAWVLTRKLSALCWNYf +>[subseq from] serine hydrolase n=1 Tax=Flavihumibacter sp. ZG627 TaxID=1463156 RepID=UPI00069388A4 +-rKLQKAIESLVEGFKGTVGIYVKHLPSGRSA-QINADTLFPTASMVKIPIMIGIMDKIH +KNELQYHQPLVYNDSLLYAGEDILGSFKSGEIQLAKVLMLMMTTSDNTASLWLQSMAGTG +TRINQLLDSMGYSATRVNSRTEGRRGHWEQYGWGQTSPREMVRLLEQIYQRKMINDTLSE +RMLRLMGRNYW-DEEAISMIPPEIFVASKNGAVD-ASRSITMLVMAPHG-PYLFSVITKN +QPDT------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1I0X2P5_SELRU +---------QVIGANNKQLAVYFLRPGREVEP-FIYNQRRMFPASMIKLFVMAKTMQDVH +DGRLSLEEQLTIRKQDVVGGAGVTTWYNTGERTVAQLIQLMVVESDNTATNMLIDKL-GM +ANINQYLQQYGYKDTMLVHKLMVNKKA---SNKNLSSVRDIGHLLTNLYYHQLVGEKEDA +FMLDILKQQRD-KECFPAVVS-GYDIAHKTGEVN-GVYADGGIFYGPQED-FILVALSNS +SE--------------------- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. Marseille-P299 TaxID=1805477 RepID=UPI000835E499 +---LLDRIKAEILSYDGLMGIYINDF-KGTKI-EINVDEEFETASTVKSYILACLYDEVQ +KGNKSLDDMLTYTSDNFIDGSGILRSDLGVTMTVKNIATLMIIVSDNIATNMIIDYL-GI +DTINTFMKNQGFSSTVLHNKLD-FEK---YDKLGTTTPRDYATLFERLCNEELVSKEASR +EMLEIFKKQHY-NSMLTKRFPQAIYVASKSGSMN-ACRNDGGIVSTPYGK-YVIVLMNKN +FHDPEHSATEFGSKVSRLIFDQy +>[subseq from] serine hydrolase n=1 Tax=Komagataeibacter pomaceti TaxID=2021998 RepID=UPI000D7BDDCF +--TLSDDIAKTIQGQPGHFAVYAAMSGQPPQV-CLNCDDFIDAASTMKLFVMDAAYDSFT +KGTLYPQDMIVVHNRSLVGGSFALYAAIGRPVAVSELLRVMIQYSSNLATNLMIERI-GV +PYVRAIVAAQHLDGIRFGRMIEDYDAN-SQGIHNQVSARGLGLFLQKLDHGDIVGPAQSQ +AMIDIMKGQKF-NDMIPPGLPPGTPVAHKTGWVD-GVRNDAGIVFLPDGRHYILVMLTKS +LP-DEAAGIRVLNTISRQVHDSf +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis benzoatilytica TaxID=346045 RepID=UPI0003810588 +---VQEQIEAVFADADTDGFLHAREIGDGPEV-SVNGDDPVVLASVFKIPLAVAYAREVV +AGRLDETERTKVTARYRTGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDLIYHRV-GQ +DAVDRVLADLGLSRTRLIGCCEDLFAVRDPERTTSSTPREMTALLDAIWTDRAADPAACE +RVRTIMAQQIW-PHRLSSGFPSGVAVAAKTGTLP-GVRNEAGVVTLGDGRQFAVAVFTRA +HSDRLPAVDGSIGAAARLALDH- +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter xinganensis TaxID=1234841 RepID=A0A223P0W5_9SPHI +--RLTIKLQEAVKGFNGQIGVYVHNLKTGKTA-AINADTLFPTASMIKVSIQCGLMDKIE +KGEMQYNQKLVYHDSLLYPGEDILGSFKDKDIEVSKVAMLMITMSDNTASVWLQKLV-GG +EYINNWLEKNGFKVMRVNSRVPGREAIRAKYGWGVTTPYEMCRLFTLIRKGEAVSAGASE +RMYRNMGRIYW-DDKAISQIPPFIETASKQGALDE-SKSETVLVNAPHGD-YVFSIITNH +NKKPDNEASVLIKKISALLWHYf +>[subseq from] Beta lactamase n=2 Tax=Rhodococcus TaxID=1827 RepID=E0D3F8_RHOOP +-------------------------IDDGGDI-AVGADDLVVLASVYKLPLLVALCRAFE +SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL +ESVERALSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE +FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA +ARTDLPVVDAAIGHAARIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. E2N166 TaxID=1851909 RepID=UPI000EF67662 +-----GRLQAAFADAGVTGWLHAVDIDSGAQV-ETGADQAVCTASVHKVCVLVTLHELAA +AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL +DAVNRTTDRLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLTALWRDEACPPEYGA +AARRVMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEIGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 01376 TaxID=2203195 RepID=A0A428XKT8_9PSEU +-----AEIEAVFANAGARGFVHAREVGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVA +AGRLDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ +EAVDRVLTDLGLTRTRLIGCCEDLFAVLDPERTTASTPREITTLLDAIWTDRAGDPAACE +RVRTIMAQQIW-PHRISSGFPAGVTIAAKTGTLP-AVRNEAGVVTDVDGRRYAVAVFTRA +ESDRLPAVDSAIGEAARLAVAH- +>[subseq from] serine hydrolase n=1 Tax=Streptosporangium amethystogenes TaxID=2002 RepID=UPI00068D4EE3 +---VSKSIQKLFADASCDGWLCVLDIDGTAEV-HVGGDDLVVAASVFKVAIAVEVFRQAD +AGHFDLQDRVRIRPNARTVGPTGFSTFADEVASIRDLTRMMLVVSDNAATDILIDRV-GL +DRVRATLTELGLKVTAIPFSLQGMLDAMQPEHAIRTTAREMARLLRLIWRDEAGPAEACA +QVRHLMAQQVT-KNRLAMGFQRDVRVAAKSGSLFGVIRNEIGVLERTDGRRYAAAVFTRA +HRINENEINTVIGTAAALAID-- +>[subseq from] serine hydrolase n=1 Tax=Nonomuraea sp. p1410 TaxID=2603600 RepID=UPI0012FCE60C +--------REIFDAAGVRGFVHARDVDDPAEV-GLDAGAPVVLASVFKIPIVLEYARQAA +KGELERTERLTVTAADKDGGIGTSGLADDVSLTLRDLAHLTLTLSDNAATDVLLRRV-GL +DRVHATLAELGLPRTRLIGGCAELFDVRDPERTTSSTPREITALLSLIWRDEAGPAEACA +EVRRIMGQQVW-PHRLTAGFDESVKVSGKTGTLW-GVRNEAGVVEYPDGRRYAVAVFLRT +TKLRDPAADAAIGRAARVAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus paucivorans TaxID=616990 RepID=A0A0R2LWJ6_9LACO +--EIKDAVTAALDPLQGTSSAYVSPVDSSQSV-VV-NNGSQSAASSIKVFILVTAYAMAK +EGVFDLDATHTVTDSEKVGGTGVIQDMDAGTLTYREVLQHMIDDSDNTGANIMIAKMGGF +SLINNKIKSMGATDTKLQRKMMDTD-AIEDGRDNTTSARDLGMTLKKIYNHQLVSKTADD +DMLEILANNRN-RAKLPKLLPSEAKVYNKTGEYDYGVQNDAEIVANKRGA-FVAVVLAQD +GK-EADQ---------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. 142MFCol3.1 TaxID=1172179 RepID=UPI00099671E4 +--QVRRTVAEAFAAAGSGGFVHAVDIDNGVQF-EYGADTPVVLASVCKIPVLVELYARSD +EGTVDLSGRVHVQATGRSPGPTGLSVMLDPAVSLRDLAYWMMSVSDNAATDVLCELL-GL +DAVNARMSGLGLKEVRLEGTCRDIYDQIPTAT--RGTPRSITTLLSMIWRDQAASPEACA +AMRRILGLQVW-PHRLRSGFPDRVAVAGKTGTLPF-VRNEVGVVEYPDGGRYAVAVFTCP +DSYANPPADAVIGTVARAAVD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=B5B4Y9_ACIBA +--------------------------------------EKFPMQSVFKLHLAMLVLHQVD +QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDQVPVQQLLQYSVSHSDNVACDLLFELVGGP +AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQPSETSPA +LLWKWMVESSTGPERFKGLLPFGTE----------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006C882D3 +-qHVDAALAPLLAATPARVSLSLRDLDGGTVL-AHHADRVQPSASIIKVPILLALLEAVA +NGRYALEQPLALPASERAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIELL-GF +DEINQWNQRAGLPASRLQRRMMDAAA-REAGRDNFTSADDATASLCWMLRDGALPAALRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Peptidoglycan-binding protein n=2 Tax=Bacteria TaxID=2 RepID=K2C2M3_9BACT +---IEQKVRNYIKDKPGNYGIYFEDLNSGQNF-SINGKEIFTVGSINKVPIIAVLYYLDN +KGEISLDSKVTIQKKDIQDGTSLRYAKPGGNYSLKNLARLSLVQSDNTAAHIIGVKI-GT +DKIQKIINSWGLTQTDMT--------------NNKTSAFDMSIIFKKIYKGEITNNAKTQ +ELLEFLTKSDF-EDRLPVLLPKQTTVYHKTGDAE-GIVSDVGIIKNEHK-LYYLGILTTD +VADKENLTKKTISEISEMVYKY- +>[subseq from] Uncharacterized protein n=2 Tax=Komagataeibacter maltaceti TaxID=1203393 RepID=A0A2S3W282_9PROT +--TLAQDVAKTVAGQPGHFAVYAAMSGQRPQV-CLNCRDYINAASTMKLFVMDAAYDMFT +KGTLHPEETIVVHNSSLVGTRSFAYAQIGRPVAVSELVRVMIQYSSNLATNLMIERI-GV +PYIHAVMDAQHLRGVRFGRMIEDYDAN-DRGIHNEMTARGLGQFMQKLDHGEIIGPAQSA +AMIDILRGQHF-NDMIPPGLPSGTPVAHKTGWVE-GVRNDAGIVFLPDGRHYILVMLTKS +LP-DEAAGIRVLNTISHQVYDHf +>[subseq from] Beta-lactamase class A n=1 Tax=Clostridium sp. USBA 49 TaxID=1881060 RepID=A0A1T4X2I5_9CLOT +-----KELKRYLDQRIGEYSFYFEDINSSYTY-SFNERIKMPSADCIKIHIAIALLKKVQ +DNFIDLYENVLIKKEDMVSGDGIIHEFDEKEYKIIELLNAMLIQNDNTAANKIIDII-GM +ESINEVIKEMGLKDTVLKRKMMDFKSH-EKGLENLTTSLDLANSLKLIYQGKYLNEEYSS +IILNSLRKSQD-RRKIPFYIPKEWKIGNKTGSLH-GVENDAAILNTKKGD-FIFVVMAKT +LP-NNVYGIVTISRLGKMMW--- +>[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A6B1FIH3_9GAMM +--KLQGELEGIVDGYEGVAGVHIIDLTSGDRF-RVNDELVFPQASSIKIPILLELFRRAE +EEPGLLRRRIDMTDEVRTGGSGVLLHLTDGGLSLEDYAIYMIVYSDNTGTNVLIDEM-GM +DEVNALSASLGAEHTLLQRKMIQPEES-ARGNENLSTPRDAALIMERIANCDLMSEASCA +RVREILEIFKGG--PIRNPVPRNVPIAFKPGGIT-GVSTVWGLVDVPDR-PYVISVMSNY +GG----DGGTVVEAVSAAAYDYf +>[subseq from] Possible beta-lactamase family protein n=1 Tax=Synechococcus sp. (strain CC9902) TaxID=316279 RepID=Q3AYZ4_SYNS9 +------WIQQAATQPDLQVSAYMLILDDGRFA-QMHANRPMPAASSIKTPILLAVLERID +QGTLQWNEPLTLTKELVGGGAGWMASRPGTRFPTYEVATEMIRVSDNSATNLMIARAGGQ +DAINARFQALDLPATVVNNWLPDLDGT------NTTSARDLSRAIALVDSGESLAPRSRD +LFREVMATSVT-NTLLPTGLMRGYRVFNKTGDIGT-AYADAGLIELPDGRRAVAGFLVKG +PFN-DPRSTEMIRQLAAAMA--- +>[subseq from] Uncharacterized protein n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A2W4QM72_9FIRM +-----SELTALAAGFSGTIGVWARSLDTGEVIrAGACDDPFPSASTIKLAIFYELMRQAG +EGKLDLDEARTLRAEDKVPGCGVLRDLTPGILPLRDLATLMMTISDNTASNMCIDAV-GI +DSVNRSMDALGLPGLRLRWKFF---CAPEGQPVNSAVPSQLGRLMDMIVRHEVLTPAACD +EMLRVMKRVQSAARYLPGGAPAGPVIAAKFGSIT-GCRHEVGAVWKGGR-GFVFSVMTKD +CKDERPEDNEGVLAVGRAVA--- +>[subseq from] serine hydrolase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=UPI0009ED4191 +---LEYKIREIMVRSIGSVSVAVEL--PYHSF-HIDGDRSYSAASLIKIPILLEAFRQAQ +EGDIFLSDMVTIPKEGRVGGAGVLVSLSDQLLTIEDLVTLMIIVSDNTATNFLIDRL-GS +NAIQELCHSLKLKHTRFLRKMMDFE-ALEQGVNNYTSALDIITCLKVLDIGKEYCQTSRG +KMLHILGQQQF-DTKLPSRMDEAVYIGNKTGELP-GVEHDCAIIKYREKT-AYIAVLIDG +LGET-ESGKDTIAQIGKLIYD-- +>[subseq from] Serine hydrolase n=2 Tax=Acetobacter tropicalis TaxID=104102 RepID=A0A511FM00_9PROT +---LAQTVARMVESQKGHFAIYAALSGQAPVV-CLNCDDLINAASTIKLFVLDAAYDAFA +KGTLRPDETITVHNRSLVGTGNFAYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV +MPIRSVVKTQGLNSIVFGRMIEDFDAN-DQGIRNEVSARGLGAFLQKLDNGQIVGKAQSQ +SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGRHYILVVLTSG +LP-DEQAGIKVLNTLSSQTYAYf +>[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2E9TI12_9BACT +--------------------------DDGKSI-LINENEVFHAASTMKTPVMIEFFKKIN +EGKISSDDSLLINNESIVDGSKFEYKNLGKYISTDKLVYDMITRSSNFGTNLLIDYL-DA +EDVNNTMKNIGAKNMKVLRGVGDLKA-FDLGLSNTTTAADLLIIYEKLAMGKIVNNESSN +KMIRILKDQVY-NDIIPKYLPEKVEVAHKTGWIS-GVRHDSGIVYVGNNEKYILVLLSKN +LE-DDIEGADFLAKISLEIYN-- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A5Q4DAB7_9BACT +--QFQATLEGLVAGYEGVAGVHVVDLTDGTSF-AVRDDFVFPQASAIKVPILIELFRRAE +SEPGLLSRRVEMTDAVRTGGSGVLRYLTDGGLSLEDHAVYMILYSDNTATNVLIDAL-GM +EAVNALSASLGAPETLLQRKMIRPEES-ARGNENLSTPRDAARIMERVADCALMTEASCV +RVQEILGIPKD--GAFVDPIPSDVPVAWKPGGIT-GVATAWGAVNLPDR-PYVLVVMSSF +GG----DGGALIREVSEAAWRYf +>[subseq from] Uncharacterized protein n=1 Tax=Haloprofundus marisrubri TaxID=1514971 RepID=A0A0W1RCN0_9EURY +-nALQARVDEYANKTDGRLGVFVIPTENGDTIaSHSSEAVFASASLIKLPILYALFDEYW +DSKSRLAQEVGLSDTNMVAGSGLLHLLSEHPYTLDDLARAMIAISDNAATNQLIDTL-GM +ERIERAVSDLGMSETRLGRKMMTTGGNLEESPVNTTSPRDAARFYRNVVRRESLSVPAYE +SLEVPLYAQKD-ASMAARYLPYDVELGHKTGWLTH-AALDAGVLHCRDGEPIVFALFVDR +LA-YAGDGTDIIAELGLAI---- +>[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora sp. XMNu-373 TaxID=2650750 RepID=UPI0013916AAF +-----------------------------GEV-DINAGNPVILASVFKIPFVVAYAREVA +AGRLDPEERTTVTARDRIGGVGTAGCADDVEMSWRDLATFMMTMSDNAATDIIYRRV-GQ +ERIQAVLDDLGLTGTRIVGCCADLFAILDPSRTSATTPRDTTTLLAAIWTGAAAPEAACA +DVRSIMAQQIW-PHRLSSGFPDEVDVAGKTGTLP-GVRNEAGVVSYPDGQKYAVAVFTRT +DVLDLPQVDAAIGTAARLAVEH- +>[subseq from] serine hydrolase n=1 Tax=Heliobacterium undosum TaxID=121734 RepID=UPI001370B561 +-dKLRQRIRKDMAESGVDYALFLEDLKSGRQF-TIEPDKNFQAASAIKVPLVLFLYALAL +DKRIDLDETMTLTSGDLAPSSGGLWSRPGRQYTLRQLAKHVIEDSDNTATNMLMRRV-GR +SNFYLFLRLAGAHTVPAG----------PG-KGNVTCARDMALYLKGIWIFRQLNPDYGE +EMFQYLLHSKI-DDRIPAGVPDHIKVANKIGSQI-GFFHDAAIVMLPNR-PYVLAILCHH +PSE--TEANAAIARISRIIYE-- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. SynAce01 TaxID=1916956 RepID=A0A1J0P8C4_9SYNE +---LSQRWKALAAQKDLKAGAFLLVLDDGRFA-QLDSELPLPAASSIKTPILLAGLEDLD +AGKLRWNEPLPLTKEVVGGGAGWMASRPGTRFPFYEAATEMIRVSDNSATNLLIKRLGGK +LALNARFQALGLGATVVNNWLPDLEGT------NTTSPHDLARSIALVDTGEKLSPRGRD +HFRTIMGTSRT-NTLLPLGLLEGVTVLNKTGDIGI-AYSDAGLIELPNGQRAVAAFMVKG +PFND-PRSADLIRAMAAAAS--- +>[subseq from] Beta-lactamase class A n=2 Tax=Actinomadura hallensis TaxID=337895 RepID=A0A543IAD5_9ACTN +---VTERIEEEFRSAGVTGWLHVVDMDSGREV-AVRADEPVVLASVFKVPLLVAFHRLAA +EGRLDPAEQVALPPRERTAPTGISGMRDEVRMSLRDLTFLMITVSDNAAADAVLDRV-GR +DAVNATAAALGLRDTVVEVSGRELHEALDPLRTSRSTPRDMTRLLSMIWRDEAAPPGECG +EMRRLFGLQVW-PHRLASGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGGRYAVAVFTRS +PLAVLPQADAVIGTAARLAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Amycolatopsis japonica TaxID=208439 RepID=A0A075UTX6_9PSEU +--AIADEIEAVFAKAGARGFVHAREIGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVA +AGRIDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ +EAVDRVLTDLGLARTRLVGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACE +RVRTIMAQQIW-PHRISSGFPAGVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA +ESDRQPAVDSSLGEAARLAVDH- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E8QTB0_9BACT +-eHLHSELSSIAERYEGVAGMHVLDLSSGDRF-AVRDDFIFPQASAIKIPILLELFRRAE +SDPGLLSKRIEMTEEVRTGGSGVLGVLTDGGLSLEDYAIYMILHSDNTATNILIDEL-GM +GPINALSASLGAPNTLLQRKMIQPEES-ARGNENLSTPRDAAEIMKRIANCELMSEIACA +RVIEILSIPKGG--PIRRPVPNAIPIAFKPGGIT-GVATVWAIVDVPDR-PYVITVMSNY +GG----DGGAVIEAAQKAAYSYf +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. 7884-1 TaxID=2021693 RepID=A0A268K749_9BACI +---LKEKIREELYGFDGRIGLAIEI-EDAGNF-YIDSEEVFRSASLIKIPILLAGLGRHK +IGELDVEQLIPISKENRAGGSGILYALSDQLLTVKDLMTLMIIVSDNTATNILIDLL-GM +DKINAFIKEIGFEHTKLNRKMMDFA-AIEKGIDNFTNSREMIHSLKLLNENDVIGITGPP +IAYHALRHQQF-RDKLPAMVNEKITVVNKTGELPS-VEHDCAIFEYQGRK-GYIAVLTDS +VI-DQNEAKQIIRNIGKHISDFf +>[subseq from] Beta-lactamase class A n=1 Tax=[Clostridium] celerecrescens 18A TaxID=1286362 RepID=A0A2M8ZC64_9FIRM +--TLEKRIEAEIMSYDGKIGIYLDDF-HGNVI-AIHADEAFETASTIKTYILACLFDEVE +KGNKSLEDMIEYKEEHVVDGSGVLPALEPGALRVKDAATLMIIVSDNIATNMMIDYL-GL +ERINQCIKALGCKDTALYNPIHF-E---QYDRLGTSTPEDYASIFIRLAKGELISPGADE +KMLDIFKKQHY-NSMITKDFPPFISVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE +FSDAAHPATVFGARVSRMILDQf +>[subseq from] Uncharacterized protein n=1 Tax=Halorubrum halodurans TaxID=1383851 RepID=A0A256IJM9_9EURY +--DLAEAIDAIADRFDGRLGVFLREVEEFDVLhRRNADGTFVAASTIKLPILYALYEAYD +GRLDALAEPRPIAAENRVGGSGIFHLLDDPTPSLEDLARATIAISDNAATNQLIDEL-GA +ERIEAAAARLGMADTRLRRKMMATLEQPDGEPANLTTPADCARFFADVVHEATLSPAAYD +RLRVPLDEQKD-ASLFARYLPYGTPIAHKTGGLPT-AALDTGVVSADDGPPLVFAAFATQ +AENG-GDAGDAVAAVGDAAFERf +>[subseq from] Serine hydrolase n=1 Tax=Spirosoma montaniterrae TaxID=1178516 RepID=A0A1P9WRH0_9BACT +--NLDLQLKDALAGFRGDAGVYVRNLRTGETV-AINADTLFPTASTIKVPIMCGLFDKIH +KGELKYGQELVYKDS-LHYDDGITGQLRDGAIPLSEVVMLMETVSDNTASLWCQALAGGG +TAINAWLDANGFPKTRVNSRTPGREAFRSRYGWGQTTPRELAELMVYIRQGRAISPDASE +EMYRNLGRQYW-DNDALSQIPPDIKVATKNGAVNR-SRSEVVLVHAPHGE-YVFCLMTKN +QQERANEGFTLLRTVSALLWRHf +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. cl95 TaxID=1761761 RepID=A0A1I6BTT8_9BACI +-nQLQVELLEIVNNCPGRASLSIDICGTSWEL---GGREVYKSASLIKVIILIEALRQVE +QGIYSLNDKFVITNDSKVGGAGVIQALSDSIFTYSDLLTLMIIISDNTATNQVIELL-GF +DSINRCCKDLGLVDTALNRKMMDFGAA-QQGRENVTTSGDMVSCLKKVNEESFLSEVGRA +EFLRIMSLQQF-QNKLPARIDEKVKVANKTGELP-GVSHDCALIEFDGKI-AYVAVLIDE +LVVT------------------- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. SYSU GA17076 TaxID=2700083 RepID=UPI0013D31F6B +------DIKKFLDSRIGDYSFYFEDLSSGYVY-AINENVRMPAAGSMKLPIAIALFKEMQ +LGKIDINMKVKVKTEDMVYSTGILHEFSERDYSVKELLTAMLLHSDNTAANKLIDII-GM +DRINEIIRDMRLANTVLNRKSIDERES-HSEIQNYTSAMDLSKCWRILYNGIFVDKENSR +IIIDILKRQQL-KNKLSYYYPERIKIANKTGDIDN-VENDTALMSINKG-SFIITVMSSN +LPN-NVYGQITLARVGKMALD-- +>[subseq from] Serine hydrolase n=2 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=A0A1W2LT78_9PSEU +--AIADEIEAVFAEAGARGFVHAREIGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVV +AGRIDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ +EAVDRVLADLGLARTRLIGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACE +RVRTIMAQQIW-PHRISSGFPAGVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA +ESDRQPAVDSALGEAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. WB9 TaxID=2594007 RepID=A0A516WPH1_9NOCA +--------------------------GDGGDI-AVGADDLVVLASVYKLPLLVALCRAFE +SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL +ESVERALSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE +FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA +ARTDLPVVDAAIGHAARIAVT-- +>[subseq from] metallo-hydrolase family protein n=1 Tax=Pseudoclavibacter sp. CFCC 13796 TaxID=2615179 RepID=UPI0013010BF0 +-----------AEAQHVKVGVTVQDLSGDAVLtAGAHDAPFKAASTIKLGLTASLMHQID +QGKLSLDTPITIQQSDLVGGSGTIQNDPTILFTLSQLIELMITVSDNTATNRLIDVAGGF +DAVNAYTQSIGLQGFHLGRKMILPHTA---EQENWISSDEDAKLLTKIYQAAIISQQSAQ +QVIAWMRAQKV-NTKFGAVVPRE-VLANKTGENTD-VSHDTGYILVPGK-EVAISVMTSF +DPTAFDTANTQVQQVAKAVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A3D3CQX4_9BACT +-kELQKKIENLLNGFHGTAGIYVHDLKKNRIV-SYQADTLFPTASVVKIPIMIGIMSKIQ +HKELDFHQWIVYKDTLNYDGEDVLASFKPDQIMVSKLMLLSISLSDNTASLLLQGLAGGG +QRINELMDSLGYVYTRVNSRTPGREKDREIFGWGQTTPREIALIMEQIVEGKVLGRRSSD +RMLRTLGRQYW-DEDAISQIPPNVFVASKSGALDE-CRNEILYVNAP--HPYIFSIFTKN +NTDQWDY---------------- +>[subseq from] serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=UPI0007083B8C +------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE +EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM +DKINETIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ +MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG +IPNS------------------- +>[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. Z-333 TaxID=2614799 RepID=A0A5J5JQ56_9MICO +------------TAAGVDLGVAIEDLSDGRSL-FAGKQDRSTTASTIKMALAVTVMQQVE +AGMLTLDDIRTILPEERYEGSGILKDGPFPQVSVGRMLDLVITVSDNTATNKLVDVVGGF +GPINATIESAGIARTDLHFGRKMFGGIVPPDGDLWLTPSGMNELLTRIYESSFLSSASAE +HIIDLMLAQQV-KTKLGATVPAG-ILAHKTGENAE-VSHDVGMVLLPGQ-EITLSVFSTV +RPDVQATANPFLQRIGTVVHDY- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A4Q3W9Z6_9BACT +-kKLESMLQNAITGFNGDVGIYVKNIRTGKIV-SINADTVFPTASIVKVSILLGVMDKIR +NGELHYDSTHVYKDSLLYAGEDILGSFRDGEIALKKIMMLMLTTSDNTASLWLQKLAGTG +TRINALLDSLGFLHTRINSRTPGREEIRKVYGWGQTSPSEMGRLFEMIYQSKVFSPAYSE +RMMRVLGRNFWDEDEAIAMIPPYIEVFSKNGCVD-ASRSEAMIVNAPNN-PYVFCIFTKN +NKKHTNEAWTLARKISTLLWEYf +>[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma fluviale TaxID=1597977 RepID=A0A286GQT8_9BACT +--ALERKLQAALSGFQGDAGVYVHNLKTGKTV-AINADTLFPTASTIKIPIQCGLFDKIH +KGELTYGQTLIYKDSLHYDDGIVGSLKDGAKIPLSEVVMLMETVSDNTASLWCQALAGGG +TDINSWLEANGFHQTRVNSRTPGRKADQTRYGWGQTTPREMAELMTYIRQGRAVSADASE +EMYRNLGRQYWD-NDGLSQVPPEVKTACKNGAVNQ-SRSEVVLVHAPHGE-YVYCVMTKN +QKERSNEGFALLRNVAALLWQHf +>[subseq from] serine hydrolase n=1 Tax=Kitasatospora sp. MY 5-36 TaxID=1678027 RepID=UPI0009EA7395 +--AARTRIAAAFADAGVTGRLHARDLDTGAEI-GLGADTAVSTASVHKLCLLVTLYREAA +AGRIDLTRQVDVPAAGRTPGSTGLGAMLDDALSLRDLAYLTAAVSDNTAADTLWDRI-GL +DTVNRTMADLGLTRTVAVHKLRDLIAVLDPAFTNHSTPRDMTTLLAALWHGDACPGDHGT +ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA +AATTLPAADAAIGTAARLAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter sp. OK268 TaxID=1881048 RepID=A0A1H0X566_9SPHI +-rKLTQQLNDAVKGFHGQVGIYVQNLKTGKTA-SINADTLFPTASMIKVSIQCGLMDKIE +KGELQYNQKLVYRDSLLYKGEDILGSFKDKDIQLSKVALLMITMSDNTASTWLQKLV-GG +DYINNWLQQNGFKVMRVNSRVPGREAIRSIYGWGVSTPFEMCRLFTMIRQGKAVSPAASE +RMSRNMARIYW-DEKALSQIPPYVQTISKQGAVD-AAKSETVLVSAPHGD-YVFSIMTNH +NTDQDNEASVLIKKISALLWHYf +>[subseq from] serine hydrolase n=1 Tax=Achromobacter dolens TaxID=1287738 RepID=UPI0011A28699 +-qHVDAALAPLLAATPARVSLSLRDLDGGIVL-AHHADRVQPSASIIKVPILLALLEAVA +KGRYALEQPLALPASERAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIELL-GF +DEINQWNQRAGLPASRLQRRMMDAAA-REAGRDNFTSAEDATASLCWMLRDGALPAALRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNT372 TaxID=1169154 RepID=UPI00036773D9 +--QVHTVLASTFDQAGVEGHVHARDLGTGEEF-GHGADSQVVLASVFKIPIALEYARQAA +AGELDPAGRHTVTAAYRAGGSGTDGCAYDVEMSARDLAFMMMTISDNAATDLLLDVV-GP +DRVRATLDGLGFPGFGFSSSAA-LDDACAPGSSPSSTPREVTALLAAIWRDEAGPASACA +EVRDIMSQQVW-QHRLVSGFPAGVRLAGKTGTDF-AVRNEAGVIEYPDGKRYAVGVFLRT +STAAQPLADRAIGRAARIAVDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter sp. OV119 TaxID=2135470 RepID=A0A318UJ23_9SPHI +-sKLTAKLNDAVKDFHGQVGIYVHNLKTGKTV-EINADTLFPTASMIKVSIQCGVMDKIE +KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQRLV-GS +EYINNWLDQNGFKVMRVNSRAPGREAMRRIYGWGVSTPREMCRLFIMIREGKAVSPAASE +RMYRNMGRIYW-DDHALSQIPPYVHTISKQGAVDD-SRSETVLVNAPHGD-YVFSIITNH +NKTPNNEAGLLIKKVSALLWNYf +>[subseq from] serine hydrolase n=1 Tax=Emticicia sp. CRIBPO TaxID=2683258 RepID=UPI00141313FD +--KLQRLLENTLKGFNGDAGVYVHHLKSGKFA-AINADTTFPTASLIKVPIMAGVFDAIR +NNKLSYKQDLVYRDSIKYDNGVVGSLKDSTVISVSKVIMLMETISDNTASLWLQGIV-GG +TRINELMDSLGLQKTRVNSRTKGREAFRSVYGWGQTTPREMATLMEKIRLGQLYSPDASD +KMYRILGRQFFEEEGL-SQIPASIKTASKTGAVNQ-SRSEVTFVHAPHGE-YVYCIITKN +QKDASNEGYELIRKVSSVLWHYf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P1ZW70_STRVZ +--QIHTTLASAFAQARAEGFLHVRDLDTGGEF-GHGADSQVVLASVFKIPIALEYARQVA +AGELDPARRHTVTSAYRAGGSGTDGCAHDVEMSARDLAFMMMTISDNAATDLLLDIL-GP +DRVRATLDELGFPDFGFSSC-AALDDACAPGTSPSSTPREVTALLAAIWRDEAGPTSACA +EVRDIMSQQVW-QHRLVSGFPPGVRLAGKTGTDFP-VRNEAGVIEYPDGKRYAVGVFLRT +STNRQPLADRAIGRAARAAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. AF28-13AC TaxID=2292234 RepID=A0A3R6LYL0_9FIRM +--TLEKRIAAELYSYQGKMSVFVDDL-QGRTV-EIGADEAFETASTIKAFILAALYLQVS +RGKASLDERITYEESQFVDGSGMLRAGVGAALKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFAHTVLHNPLH-FDR---YRDLGTTTPRDYAALFAQVAKGTLVSREASA +EMLAIFRQQHY-NTMLTHDFPERIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] serine hydrolase n=2 Tax=Apibacter sp. HY039 TaxID=2501476 RepID=UPI000FEB743B +--EFNDSIYHLIKNKKLDIGISVRDNTGDEIV-SYNQNKKYKLYSVSKYFLGLYILDQVD +KGNLNLNQPVIFSKKDLKPYSPLRDSNPGTTLTLKESIKYLIEDSDNNVFDKLIDISGGF +QRLNLFVHQIVPNKFAINAGYSDSETL---FQSNVITPSLTTEILYKMENRQIISDESLN +LLKFYMQHSVN-NKRIQGLLQTKTKSFHKSGTSGRKATNDIGIVELQDEQSFSIAVFISN +SHEDDATNEYIIAKLADIIYD-- +>[subseq from] serine hydrolase n=1 Tax=Sphingobacterium psychroaquaticum TaxID=561061 RepID=UPI00106CD49C +-kKLEERLKKETENFQGDIGIYVQHFKKNTTV-NILADTIFPTASIVKVPILVGIFNKIN +EGSLTLRQPFRYDAKRVYGGSGLMQFYKDSATELSIMISLMLTYSDNVTSIWNQELAGGG +VEINRIMDQLGLVNTKVNSRTTGREQLWRKYGWGQTTPKEIASLMHLIRSGKVFNPQLSD +KMYRYLKNQFY-NERSLSQIPAEIATASKTGSVDD-ARGEVVYVHAPSGD-YVFSVLTKN +NKTDENEAEKITRKIASIIWNYy +>[subseq from] Uncharacterized protein n=2 Tax=Bacteria TaxID=2 RepID=K2ABK7_9BACT +--ALKKQIQEVVRQQTGSYSVYFSNVDDGRLSfGINENFIHTAASVNKVPIVVTLYYLAS +QNKINLDEKITVQENDIQDTGSLRYEEPGRSYSLKTLAKLTLEQSDNTAAHILAQKI-GT +DNIHEVIENFGLTQTSMEN--------------NKTTLTDMHILFKKIYSGEIANKALTN +ELLDFLKDTDI-EDRIPKLLPEDTVVYHKTGDAV-GIIHDVGIVEQSNNA-FFVGIMTSD +IGNREEETKNAIAKIAKIIFD-- +>[subseq from] Serine hydrolase n=1 Tax=Achromobacter sp. TaxID=134375 RepID=A0A5N7YUH8_9BURK +-qHLDATLTPLLAATPARVSLSLRDLDGGVVL-AHHAERAQPAASIIKVPILLTLLAAVA +EGRYTLEQPLALPAADRAGGTGILAQLPGVTLSLAELARLMIVLSDNVATNALIDLL-GF +DAVNQWNPAAGLTASRLQRRMMDAAA-REAGRDNFTSAGDATAALCWLLRDGALPAPLRA +FALDVLADQRE-RAHFGAALPAAAHLASKAGQLP-GLRHDAGILTVDDC-SVVLAVLADG +FT-DWQTAHTLHGGAGAA----- +>[subseq from] serine hydrolase n=1 Tax=Nocardia arthritidis TaxID=228602 RepID=UPI0009FD5742 +------SVQEIFRTAGVEGWVHTQCVDCGAQA-GTRADEPVVLASVVKVPLVLEFARQVV +AGQLDPADRVRARAADRLGGVGTAGCTDDVELSLRDAAYFALTVSDNTAADLLFDRV-GL +DNVRSLLRELGLTATRVVGPPRAVVQALDPRRTTASTPREMVRLLTLIARDQAGAPEACR +WVRDLMRQQVN-WYRLAAAFPPEVGVWAKTGTLP-GVRNEIGVVEYPDRKRYAVAIFTRA +ATQRLPEVDRAIGAAA------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. AcE210 TaxID=2292703 RepID=A0A371XP13_9ACTN +--AIADEIAAVFAEAGAQGFLHAREVGDGPEV-AVGADAPVVLASVFKIPVAVAYVREVA +AGRLDETERTRVTARYRIGGIGTAGCADDVEMSWRDLALFMLTMSDNAATDVVFHRV-GQ +DAVDRVLTDLGLSRTRIRGCCEDLFAVLDPDRTTSSTPREITRLLDAIWTDRAADPGACE +KVRAIMGRQIW-PHRISSGLDTGVQVAAKTGTLP-AIRNEAGVLTYPDGRQYAVAVFTRA +DADRRPAVDTSIGRAARLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces luteocolor TaxID=285500 RepID=UPI0008534269 +-----------FAAAGVTGRLHALDIDSGAEV-DAGADQPVVTASVHKLCLLVTLHEQAA +AGVLDLTEQAECPAEGRTPGPTGLAAMLDPVMSLRDIAFLMMSVSDNTAADLLLERV-GL +DAVNATTARLGLERTHATHAFRELLAALDPARTNRSTPRDMTRLLRAVWRDEACAPEHGA +AIRRVLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVIEYPDGGRYAVAVFTRA +AGAILPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Virgibacillus sp. YIM 98842 TaxID=2663533 RepID=UPI0013DC5225 +---------------------------D-GDI-GIEEEKVYSSASTIKVPILIEALRQAE +QGIINLDEKVTVTDEDITSGGGIIRHMSDNQLSLRDLLYLMITQSDNTATNMIIERV-GM +GSVNQASAEMGAEDTILQRYMMESVT--P--RDNLTSAKDMATIMQTVYEGDILSSESEA +EFLRMMAEGIL--SHYKGDDHSGVSLYSKGGSLGTNVRHNIGMFTHEDEA-VYVSVMSQN +AS--LKDSRIKMAEIGERVMDY- +>[subseq from] serine hydrolase n=1 Tax=Microbacterium oxydans TaxID=82380 RepID=UPI001431CD09 +-----ASIAEIFADAGATGFLHAREIGGGPEV-SVDADEPVVLASVFKILVLTAYVRAVA +AGELDPTERTTVTARYRIGGVGTAGFSDDVEASWRDLAQNMMTMSDNAATDVVYHRL-GS +DAVNRVISDLGLRQTRLVGCCEDLFAAVHPIKTSHSTPRDVTTLLDALWTDTAAPAEACR +QARDIMAQQIW-PHRLSSGFPSGVRVAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA +ASERQPLVDASIGR--------- +>[subseq from] Beta-lactamase class A n=2 Tax=Mycolicibacterium mucogenicum TaxID=56689 RepID=A0A495CTW7_9MYCO +-dTLTAQIAEVAEDAGVFAFAHARDIDTGVEV-GFRSDDPTVTASVFKVPVLVEYVRQVA +AGELDPAQRIEVSPSEATMGPTGLSVFSDVAWSLRDIATSMITVSDNAATDIVTGLV-TV +DRVNSTMRELGLPGTQLTGDCSVIFDAATPEKTNRTTPREATSLLQQIWTDAAATPEACA +EARRILGMQVW-PHRLSAGFPDDVKISGKTGTIGM-VRNEIGVVEFPDGTRHAIAVFLRG +KTSRNPAADRAIGDIARLLSD-- +>[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7PWA8_9BACT +---LRLEIEKEIKNFPGKVWISACNLNKGIAF-NLAGDERVRTASTIKLPILVALHGEVK +EGRLSWEEKLVVTKKTRAQGAGILLEMDDGHLTLREASKLMVVVSDNIATNLILERM-GI +DKVNAWMDKLQLPKTRSLAWIGEVVSRADGSTYGVTTPNEMVNLLTRLAQGEIISPEDSK +QILALMGRQQY-KDGIGRNMR-GASVANKPGALDR-LRSDVGIITVGKE-KFALAITLDD +MTPDWSPDNAALK---------- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7SLM3_9BACT +---LRRTLDSLASAHHGVVGYSVLDVDTGERL-SRRGDETFPTASLIKVPILVTVFDLVE +QGQLSLDDQLTLLKIDKVPGSGNLQFMHDNALTVRDAAWLMSVTSDNTATNLLLDRI-VI +RRVWDKMEKLGLPHTKVHSKTYLRMASSVKYGLGVTTPNEMVRLFALLAEGKAVSQKGDS +TMLDILAHNDD-FELMQRYID-GLTVPHKTGSTDQ-VRTECALFPLQSR--VVACVLTKE +NVDQDNEAQVTLANMGRAIAGAw +>[subseq from] serine hydrolase n=1 Tax=Lacrimispora aerotolerans TaxID=36832 RepID=UPI00047E82C1 +--TLEKRIEAEIKSYDGVMGIYLDDL-RGTVI-QIKADETFETASAIKTWILACLFWEAE +KGRACLEDQIEYKKEHWVDGSGVLGTLEPGALRVKDAATFMMIVSDNVATNMMIDYL-GL +DRINQCIRRLGSMDTVLHNPIHFDQ----YERLGTSTPRDYASIFVRLVKGELISPEADR +QMLEILKKQQY-QSMITKDFPPYITVASKSGSMD-ACRNDGGIVFTPYG-PYVIVMFHKE +FSDAAHSATMFGARVSRLMLDQy +>[subseq from] Serine hydrolase n=1 Tax=Selenomonas sp. TaxID=2053611 RepID=A0A357Y1H8_9FIRM +--ALAAHIEALSNGDSTHYEVFVAYPLENREY--VYQSAPMRSASMIKVFILATAMERVK +AGTLALDQTLTLHSSDKVGGAGVIAGYASGTLSLDTVMRFMITESDNTATNMMIDLL-GM +DAINAYIQQHGYHDTSLQRKMMDSA-AVAAGRDNYTSAADLGHFFVTLYNRCCVSPELDD +VMLGYLAGQTD-TECFPAAMP-GVMIAHKTGELG-GLYDDGGIIYQEGR-PFIMVGMTEH +YS--------------------- +>[subseq from] hypothetical protein n=1 Tax=Prevotellaceae bacterium LKV-178-WT-2A TaxID=2606637 RepID=UPI0012B29246 +----------------------ACLIKDGQFY-GIHENKYFPMNSVMKFPQALFVADWMK +KHNIRLSDSVKVTKEELIDWSPKLGDIQTSKFTYAELLSYSLMLSDNNACDVLFKRCGDP +KTVEAYVRSLGFKRIHIRKTERQMREDHSCCRHNKTTPKDMTLLLQWLSSHH-SDTPILQ +FIWETMMKCKTGMERLPAAKHEGAMLLHKTGSGYTADIGDAGIYLLSDGSKLPICVFVKG +ASS-----DHIIAEISQ------ +>[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora sp. HAJB-30 TaxID=2715536 RepID=UPI00140B411E +-------------------HVHAVALDRHREI-GVRADEPVVLASVFKLPLALAYARMVD +SGELSATDAVELVPGIRTPATGVAAMADPVTMSWRDAVRSMMTVSDNAAADAILDVV-GV +DRVAATLRDLGLTSTRVPGGTRDLYADAADPRNNVSTCREMTRLLSAIWTDRAASAQQCA +FIRSVMSQQVW-TQRLAAAFPDDVVVSGKTGTFV-ALRHEVGVVEYPNGESYAVAVLTMS +ARARLPAADDAIAQAARLAV--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces rubrogriseus TaxID=194673 RepID=UPI0013DBDED2 +----AARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVTLHELAA +AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL +DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGSVWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHMAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. ZL-24 TaxID=1933029 RepID=A0A2S3XXD7_9ACTN +----ERTIRSLFDDAGVRGWLHVAELDRSARV-ALDPDEPVPMGSVYKIALMAAFCRLAD +AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLAVQMMSISDNTAAHAVLRAV-GT +DAVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDEAASPESCA +FMRAAMGTQPW-THRLASGFPDDVAVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces griseocarneus TaxID=51201 RepID=A0A3L8IRS1_9ACTN +---TTGRIRAAFAEAGVTGRLHAVDIDSGAET-GVDGDHRVVTASVHKLCLLVTLHELAA +AGRLDLTERIECPADTRTAGPTGLAAMLDPVLSLRDAAYLMMAVSDNAAADILLERV-GL +DAVNRTTARLGLARTHAVHTFGQFLAALDPARTNHSTPRDMTRLLGAVWRDEACTPEHGA +AMRRVLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA +ASAVLPPADAVIGTAARLAVD-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Candidatus Shapirobacteria bacterium CG10_big_fil_rev_8_21_14_0_10_40_9 TaxID=1974888 RepID=A0A2M8L313_9BACT +----TLEISDLVKNLKGEYGIYVFNLTTKQGY-GVNEDEIFPAASLIKLPVFLTLYQEAE +AGRIDLSSKYTLKNSDKQAGAGGMQKSAGTVYTYRQVAELMGKQSDNTAFFILRKIL-GD +EKIQKTIDNLGMTKTSLVKNE--------------TTSQDLGLFFRKLYAGSIVSREHRD +EILGYLTETFD-ETRIPAGVPEGTRVCHKIGTDI-GVISDAGIVFSP--KPFILVIMSKN +VL--EKEAKEVLPKITEAVWE-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodohalobacter barkolensis TaxID=2053187 RepID=A0A2N0VFY8_9BACT +-----EQILELTKGFNGDIGIYVKDLESGAEF-EVNADTIFPTASMVKIPILVKIFDKIE +QGELEYQMELDYGPEPEYEYSGISNLIPGTEVSLSELVHMMMSTSNNTASLWNQYLAGTG +TEINQWLADHGYVATRVNSRTEDRGEDFETYGWGQTTPREIARLVGQIYRGEVVSSHACE +QMYRIMSRNYW-DGEALSQIPPTVNVASKNGAVR-ASRSEVLLVNAPSGD-YLFSVITKN +QEDSDNEAWVLIRNLSALLYNHf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. WAC08241 TaxID=2487421 RepID=A0A429Q7P5_9ACTN +---IHTTLASVFAQARAEGLLHVRDLDTGAEF-GHGADAQVVLASVFKIPIALEYARQVA +AGELDPARRHTVTSAHRAGGSSTDGCAHDVEMSARDLAFMMMTISDNAATDLLLDIV-GP +DRVRATLDELGFPDFGFSSC-AALDDACAPGTSPSSTPREVTALLAAIWHDEAGPASACA +EVRDIMGQQVW-QHRLVSGFPPGVRLAGKTGTDFP-VRNEAGVIEYPDGRRYAVGVFLRT +STAAQPLADRAIGRAARAAVDH- +>[subseq from] Putative beta-lactamase (Penicillinase) n=1 Tax=Deinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923) TaxID=546414 RepID=C1CYR0_DEIDV +-----------QRGFAGDTGLRICDLDGTELY-ALNATRTFPAASTIKVPLLIQALQEAQ +TGRLNLRERVTLEAADRVPGSGILYELGAGLPSWLDLLTLMVIVSDNTATNLVIARL-GP +DEINSWLARGGWSSTRLIGRLEQQNEAQRRGERNRTSAHDQVDLLLRLANGALLDRTHTD +LALSILSRQQL-RDIIGRRVPRSYRLVSKSGELT-GVHHDVGILYTP--RPLVIALLSEA +GQREHPENRDVL----------- +>[subseq from] Serine hydrolase n=1 Tax=Lachnoclostridium sp. TaxID=2028282 RepID=A0A3D1FT08_9FIRM +------EIIKKLEQLPGKIGFFYENLKTGDGF-AHHEQEPMMAASVIKLFVMTAAFEKEK +KGTFQMDELFAVKREDCVPCGALTYLHDGILVTGMDLITLMIIFSDNTATNILIDIL-GM +DEINETIWGLGFRQTLLQRKMYDMESS-AQGIQNYITAYETGRLLKMMYDGILIDRQSSE +TMISILKNQQL-CSKIPFYLQDSPEIAHKTGEDT-GITHDVGIVYG--MEPFLICFCGNE +T--DTPAFERIMAEIS------- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A537JI66_9BACT +-kKLDSKIRSLVQDYHGDIGVYVKSLKNGSIV-TINADTVFPTASIVKVPIFVGVMDKIN +RGELFYDSSLIYKDSLLYEGEDILGSFKSDEILLKKVIMLMLTTSDNTASLWLQSLAGKG +TRINAILDSLGLKYTRVNSRTPGRETNRNIYGWGQTTPLEMGKLFEMIYRNQILSAAICE +RMMRCLGRNYWDEDEAISQIPPLIEVFSKNGCVD-ASRSEVLLVNAPHN-PYIFCIFTKN +NKTHFNEAWALARRISKLLWNYf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL F-5630 TaxID=1463864 RepID=UPI000692608B +--AVADRIAAAFADAGVDGAVHAVDIDRGTQA-GHGADRLVCTASVHKLCLLLALHRLAA +AGRLDLTEQVECAVEGRTPGTGLAAMLDASRMSLRDLAYLMIAVSDNAAADLLLARV-GL +EEVNRTTRALGLRHTRAVESFAAMQEALDPTHGNRSTPRELTRLLGAVWRDEFLPEAHGA +AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEAGVVEYPDGGRYAVAVFTRA +ADHVVPAADAVIGLVARLAVD-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X0WK93_9ZZZZ +-eRLKKQIEGVIRGTEGEVGVAVKHLESGQEL-YINGDMNFPMASVFKVPILVEVLAQIK +EGKFTLKDEISIQKTDQHLGSGMLSDLEAPGLSLRNLITMMMIISDNSATDILLTKV-GA +ENVNNRLRSYGIGEITVNRTCQQLIMKFTQIMKDQSTPRAMNRLLEMIYKKEVVDEESCD +LILSVMLEC--------------------------------------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFCSPHIGHO2_01_FULL_40_15 TaxID=1798376 RepID=A0A1F5Z080_9BACT +--EIKTDINKELANTTGTFSVYFYDLKTGDNF-GINEDIVLTAASVNKIPILAALYHLAG +KDEIDLDKIIVPQQKDIQDTGSMRYDKPGTPYSIKTLARLMMEKSDNTAAYLLASVIIGM +DEIQKLIEEWGLTQTDME--------------NNKTSVKDMFVITKKIYNGEISSEELNK +EMVDFMDDSDF-EDRISRGVPETITFYHKTGDEV-GKVHDVGIVDLPER-PYFLGILTTD +VT-DVEETKDKIARISRIVFS-- +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A2A6ZJD8_9FIRM +--TLEKRIEAELYCYQGKMSVFVDDL-QGHTV-EVGADEEFETASTIKAFLLAALYLQVQ +RGKADLSEEIEYEQSQFVDGSGMLRAGVGAKLRVKDTATMMIICSDNIATNMLIDYL-GL +DAINACIRELGFAHTVLHNPLHF-DR---YRKLGTTTPRDYAALFARIAKGTLVSAQASA +EMLAILRQQHY-NTMLTHDFPQYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKE +FHD-------------------- +>[subseq from] Uncharacterized protein n=3 Tax=Ktedonobacter sp. TaxID=1932716 RepID=A0A3D2MRZ5_9CHLR +----QASIEQELSTLGGHVACVVIRMTDEQELvSINADHVFPAASLAKVPLLIEVARQVE +FGMLCWETRYLVWEGARVASDGVIADLSADLPTVQDLAHLMIAISDNTASNMLLDIV-GM +DAVNATMSNLGLTDTRIERRFIDFEAR-KAGYDNWTTAADMALLYSFFFTE-LLP-GKKK +MLKMLLRQND--YTILPAYWGEKTPFAHKTGGLA-GIIHDAGILYAPTHTPLIIVIMTSE +QV-DEPLTRYTLARVGRIIY--- +>[subseq from] Beta lactamase n=1 Tax=Amycolatopsis azurea DSM 43854 TaxID=1238180 RepID=M2QEI0_9PSEU +--AIAEEIEAVFAKAGARGFVHAREVGGGPEV-GVGADDPVVLASVFKIPVAVAFAREVA +AGRLDDTERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRI-GQ +DAVDKVLTDLGLTRTRLIGCCEDLFAVLDPERTTASTPREITELLDAIWTDRAGDPAACE +RVRAIMAQQIW-PHRISSGFPAGVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA +ESDRQPAIDSAIGQAASLAVEH- +>[subseq from] Beta-lactamase class A n=1 Tax=Hungatella effluvii TaxID=1096246 RepID=A0A2V3YAD8_9CLOT +---IEKRIEAELMSYDGTMGIYADDF-HGNVI-AIGAEEPFETASTIKTYILASLFDQVE +KGKASLEDMVEFKEKHTVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL +DTINACIHGLGCRDTVLHNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPEADA +KMLEIFKKQHY-NSMITKDFPAVVNVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNKK +FSDAAHPATVFGARVSRMLFDQf +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2G4FWL3_9BACT +---LRRTLDSLSAAHHGVVGYSITNLDTGEHL-EQRGNETFSTASLIKVPILVTLFDLAA +QKLLTLDDPIVLTEIDKVGGAGQLQYLRTPLLRLWDVAYLMSTLSDNTATNLVLDRI-KI +RRVWQKMEALGLAHTKVHSGSMTRIASSAKYGLGVTTPNEMAQLFTLLAQGKAVSPLADS +TMLDILANNQD-DSKLARY-TYGTRLAHKSGDVD-ASRTDCGVFTLPAR--VVACVLTKE +NTDTDAEGNAVIGRIGEAIVKAw +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. UW140 TaxID=368503 RepID=UPI000E0E6660 +------RWRQLAAQQDLKVSAFMLVLDDGRYA-ELNPDTALPAASSIKTPILLTTLELLD +SGSLRWNEPLTLTKPVVGGGAGWMATPLGTRFPTHEVATEMIRISDNTATNLLIERAGGK +KVINTRFNALGLSATEVNNWLPDLQGT------NTSSARDLARAIALVDTGKALSTRSRD +LFREVMGTSVT-NRLLPGGLLKGYRVYNKTGDIGI-AYADAGLIELPDGSRAVAAFMVQG +PFND-PRSTELIRNMAAAM---- +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. 7K534 TaxID=2530366 RepID=A0A4R4MSU3_9ACTN +--EVAERIEAEFRAAGVTGCLHVVDMDSGREV-AVRAGDPVVLASVFKVPLLVAFHRQAA +EGVLDPAEPVVLGPADRTAPTGISGMLDEVRMSLRDLTFLMITVSDNAAADAVLDRV-GR +DAVNAAAAALGLSDTVVEVSGRELHEALDPLRTSRSTPRDMTRLLSMIWRDEAAPPDGCA +AMRRLLGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGGRYAVAVFTRS +LLAVLPRADAAIGTVARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces atroolivaceus TaxID=66869 RepID=UPI0009986049 +-------------------HVAELN-SPSARV-TVDPGEQLPMGSVYKVPLMVAFCRLAD +AGLIDPGRRLTLEPGERVPPTGISILHDSVTMSLRDLVVLMMTISDNTSADAVLRAV-GA +EVVDAMCRDLGMPDTHIRGGVVTTFSVYDPAFKASTTPADMARLLRAIWTGRAASDERCA +FMRDVMRRQPW-THRLASGFPDDVTVYGKTGSFG-ALRHEAGVVELADGSTYTAVVFTQA +ARAKLPRADAVIGAAARTAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Beckwithbacteria bacterium CG10_big_fil_rev_8_21_14_0_10_34_10 TaxID=1974495 RepID=A0A2H0W846_9BACT +---LENSLNFLLKDLQGEYGFYYFNFNTKEEL-GINENQVFQAASVNKLPIMISFYQEVE +KGNLKIDSLYVLDKEDFQDGSGVLHTQEQGIYSYEELVKLMGKHSDNTAAYVMARIV-GY +KKIRDYLDKYEMNNTTLDD-------------NNTTTPKEMGNYLRLFYENELIGVENKE +KILEFLTQTDF-EDRLPQGVPSYIRVAHKTGNLA-GVYNDCGFILSS--KPYLVCVFSQD +TLE--QQALDVIPKIAEILWEY- +>[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus thermotolerans TaxID=338644 RepID=A0A3S6Z2E4_9FIRM +--NIHQAIAQWSQHFSGRFTLYAEHLQTHEVV-AHEPTRLMETASVIKLPIMIAAMDQVE +AGHLDLATPLVYTRDDYVEGSGVVQNLTPGFLSLHDALTLMITVSDNVATNMVLRQI-GL +ETVNAVMHRLGTPHIHLYKRIDFAQ----PGPIGLAPAEEIGVLLKSLYHRTLISPWASG +IMWDILTRQQY-NTIMTRELPYHVQIGSKSGSLE-GIRNDVGIVTSKWGD-YTVAIFSAE +CEHVDNEAMRLLPRLTRLLFDHf +>[subseq from] Serine hydrolase n=1 Tax=Arsenicibacter rosenii TaxID=1750698 RepID=A0A1S2VDS4_9BACT +--KLERLLRDALAGFRGDVGVYVHHIKSGKTV-SINADTTFPTASTIKIPIMCGLFDKIN +KGELKYQQEIVYKDSLHYDDGIVGSLKDGAKFPLSQIVMLMETISDNTGSLWCQALAGGG +TAINSWLDANGFSKTRVNSRTPGREAFRPTYGWGQTTPHELAELLLYIRQGKAISPDASD +RMYRNLGRQFWDGDGL-SQLPEGIKVATKNGAVNR-SRSEVVLVHAPHGE-YVYCIMTKN +QQERTNEGATLLRKVGALLWHYy +>[subseq from] serine hydrolase n=1 Tax=Spirosoma panaciterrae TaxID=496058 RepID=UPI00036792F6 +--RLERKLQSALAGFRGNVGVYVYHIRSGKRV-SINADTLFPTASMIKIPIQCGVFDKIH +KGELSYNQELVYKDSLHYDDGIVGSLKDGARITLSKVVMLMETVSDNTGSLWCQALAGGG +SAINTWLETNGFHQTRVNSRTPGREANRTQYGWGQTTPHEMAELLVYIRQGKAVSPDASD +EMYRNLGRQFWDGDGL-SQIPPDVKVATKNGAVNQ-SRSEVVLVHAPHGD-YVYCIMTKN +QQERTNEGYELLRTVGALIWHHf +>[subseq from] Beta-lactamase class A n=1 Tax=Microlunatus soli TaxID=630515 RepID=A0A1H1UDK5_9ACTN +-qEFTRRLDVLLAAADVRGWVHAVDLDSGASL-EAGADQPVVAASVFKLPVLVELFRQIG +VGRLDARQRVRIGADERRTPTGLSV-MLDDVLSLRDLGYAMMSVSDNRATDVIVDLV-GL +DAINNTQAELGFPATVLEGDCQFLFDVFDPLRTNRTTPRSTTALLAMLWRDEILDPSACA +EIRRILSLQVW-PHRLTSGFPDEISVAGKTGTIGP-VRNEVGVVSYPDGGRYAVAVFLRQ +REYHNPVADAAIGQVGRLAIDH- +>[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium sp. JB170 TaxID=1434842 RepID=A0A1R4KKN4_9SPHI +-kKLTKIIEQEIASFDGEIGIYVENFKKDITV-EIQADRIFPTASIVKIPILVGVFDKIN +DGSLNLSNSYIYDAKREYGGSGLMQFFKDSATDLSTIVSLMLSYSDNVASIWCQELAGGG +QNINRIMDELGLKNTRVNSKTAGREDDWNQYGWGQTTPKEIATLLAKIRFKKVYDNRLSD +KMYRYLKNQFY-NERSLSQIPAEIATASKTGSVNE-SRGEVVFVHAPSGD-FVFSILTKN +NKTPDNEAEVLTRKIAKLLWNYf +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter senegalensis TaxID=446692 RepID=A0A149U6W1_9PROT +---LAQSISKTVKAQPGHFAVYAALSGHSPAV-CLNCDDLINAASTIKLFVLDAAYDAFT +KGTLHAQDTVTVHNRSLVGNGTFAYAQAGKPVPVSELLRVMIQYSSNLATNLMVEKL-GV +MPIRSVVKAQGLDGIVFGRMIEDFDAN-DKGIRNQVSARGLGAFLQKLDNGQIVGKAQSQ +SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGKHYILVVLTSD +LP-DEQAGIKVLNTLSQQTYTYf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces atriruber TaxID=545121 RepID=UPI0006E3F336 +--------------AGVTGRLHAVDIDSGAEL-DAGADQPVVTASVHKLCLLVTLHQQAA +DGELDLTEQVECPAGLRTPGPTGLSAMLDPVMSLRDIAFLMMAVSDNTAADLLLARV-GL +DAVNATTAALGLDRTHARHTFSELLAALDPARSNRSTPRDMTRLLTAVWRDEACAPEHGA +AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA +AGAILPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Actinomadura echinospora TaxID=1992 RepID=UPI000CDF1554 +---------------GVVGCLAAIDLDDGRLV-GVRADRPVVIASVLKVPLLVALHRQAA +AGIVDLSEQVVLRPGERTTPTGVAVLQDEVRMSLRDLAAMMITVSDNAAADTLFARV-GV +ETVNAVLAELGLHRTHIPGCCRELFDALDPARTARSTPEEIAQLFAAIWRDEAAPAAECA +RMRRLFGLQVW-PHRLASGFPDDVQVSGKTGTLPT-IRNEAGVVEYPDGGRYAVAVFTRS +LSSVLPRADAVIGTTARMAVEH- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0001F41FEE +-qHVDAALAPLLAATPARVSLSLRDLDGGTVL-AHHADRVQPSASIIKVPILLALLEAVA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNAATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Serine hydrolase n=1 Tax=Goodfellowiella sp. AN110305 TaxID=1892852 RepID=A0A5B2XE67_9PSEU +--AVAEEIAAVFADAGARGFLHAREVGGGPEM-AVGADDPVVLASVFKIPVAVAYAREVA +AGRLDETERTRVGARYRTGGIGTAGCADDVELSWRDLARFMLTMSDNAATDVVFHRI-GQ +AAVDRVLTDLGLTRTRLVGCCEDLFAVLDPDRSTASTPREITELLDAIWTDRAGDPSACE +RVRSIMAEQIW-PHRITSGFEPGVRIAAKTGTLP-AVRNEAGVVTYPDGRRYAVAVFTRA +HSDRQPAIDSAIGRAARLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. 111WW2 TaxID=1945515 RepID=UPI000D0C7D79 +-------------DAGVTGWLHAVDIDSEAQV-GAGADQPVCTASVHKLCVLVTLHELAA +AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL +DAVNRTAARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLGAVWRDEACPPEYGA +AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. TMED169 TaxID=1986593 RepID=A0A1Z9JA23_9SYNE +--ALSRRLAEIASQKDXKVGAFVLVLDNGTYA-ELHPDRPLSAASAIKTPILLVALEALD +QAKLTLXEALSLXKTVVGGGAGWMGGQPXGSFSVLEVATEMIRVSDNTATNLLIQRLGGK +QALNSRFLELGLEGTVINNWLPDLKGT------NTTTPRDQARAIALVETGQALSVRSRD +LFRQTLGTSRT-DTLIPRGWLRGVRAYNKTGDIGI-AYVDSALLELPDGRRVVASYMVEG +PFND-PRSTNMIRALAAA----- +>[subseq from] serine hydrolase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI0007AB3F9D +----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIRRMEKNTVGGAGVLRALPRLTIKVEELLALMIMVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE +KIIRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLITDIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=UPI0009B8F658 +--------AQVIGANNKQLAVYFLRPGREVEP-FIYNQRRMFPASMIKLFVMAKTMQDVH +DGRLSLEEQLTIRKQDVVGGAGVTTWYNAGERTIAQLIQLMVVESDNTATNMLIDKL-GM +ANINQYLQQYGYKDTLLVHKLMVNKKA---SNKNLSSVRDIGHLLTNLYYHQLVGEKEDA +FMLDILKQQRD-KECFPAVVS-GYDIAHKTGEVN-GVYADGGIFYGPQED-FILVALSNS +NEG-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 04197 TaxID=2203199 RepID=A0A429E8X8_9PSEU +--AIADEIEAVFAEAGTRGFVHAREIGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVA +AGRIDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ +EAVDRVLTDLGLARTRLVGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACE +RVRTIMAQQIW-PHRISSGFPSGVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA +ESDRQPAVDSALGEAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Ferruginibacter sp. BO-59 TaxID=2294116 RepID=A0A3M9NDW9_9BACT +--RLQAMLTRLVDGFHGDVGIFVYDLAKNKIA-SVHGDTIFPTASMVKVPILTGLMHKIH +NGDFTYHQEMLFTDSVRYSGQEILASFRDSTIPLNELVMLMMSMSDNGASLWLQGLSGGG +AQINSYMDSLGLKYTRVNSRTAGRKENYNLYGWGQTTPKEMATLMKMIAENKIINQQISE +RMLRMMSRQFW-DEDAISQIPPNVFVADKSGAVD-ATRDEV--LYVNGNHPYIFCVCTKN +NREHDNEAWVLTRKLSALLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Niastella populi TaxID=550983 RepID=A0A1V9FTJ5_9BACT +-hRLQQQIEALVKDLHGDIGVYIKNLRTGKVA-MVNADSIFPTASMVKVPILIGIQDKME +SGQLEYHQQLEYKDSLLYAGEDILGSFKSGEIGLHKVLMLMLTTSDNTASLWLQSLAGTG +TRINELLDSAGMKFTRVNSRTPGREANRQQYGWGQTTPREMGTLMEKIYRGEIISKKAGE +KMIRLLGRNFN-DEQAIAEIPPYIFVASKNGCVN-ASRSEILLVMAPGG-PYIFSVQTKN +LQDNSNEAWVLTRRLSALCWNYf +>[subseq from] Uncharacterized protein n=1 Tax=Nocardia sp. CS682 TaxID=1047172 RepID=A0A4P7HB89_9NOCA +------------------------------------------------------------ +------------------------------------------------------------ +-------RGLGDPVSRMDQYEPELNRDPPGDDRDTTTPRAIAADYQQLILGSALPEDKRT +ILTDWLVRNVTGAKRIAAAAPAGWTIADKTGTGDYGRANDIAIVWPTAHPPLVLAIMSDR +TGYDAEPSSELIAEAARHIF--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. AW19M42 TaxID=1379686 RepID=UPI000D12A41E +-----------------WLHVAELHHPSARVV--IDPGEQLPLGSVYKVPLMAAFCRLAD +TGRIDPRHRVTLESADRVPPTGISVLHDPVTMSLRDLVTLMMTVSDNTAAAAVLRAV-GA +GVVDAVCRDLGMPDTRIHGGVVTTFSVYDPAFKASGTPADMARLLRAIWTDEAASAEGCA +FMREVMRRQPW-THRLASGFPDDVTVYGKTGTFGS-LRHEAGVVELADGSTYTAVVFTQA +ARADLPRADAVIGAAARAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Candidatus Kryptonium thompsoni TaxID=1633631 RepID=UPI000707E2B9 +------------------IGVAVKNLETGETF-FINENLIFPQGSAIKIPILIEVIKQAS +EGKFKLTDKIKIEKKHQVGGSGVLKEFGDGTLSIYDLAVLMITVSDNTATNILIDLV-GM +ENVNKTLEKLGLKNTKLQRKMIRPDAS-ARGEENLSTPLEAMKLMEMLYKGEVISKEISN +QVIDILKKKKR------------------------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. A7024 TaxID=1128680 RepID=UPI0013EB1EFD +------RIQAAFTDAGVTGRLHALDIDSGAEI-DAGGNRPVVTASVHKLCLLVALHERAA +AGQLDLTEQVECPADGRTAGPTGLAAMLDPVISVRDLAHLMMSVSDNAAADLLLDRV-GI +DAVNATTDRLGLAATRMSHTFGGLFAALDPAHSNRSTPRDLTGLLRAIWRDEACPPPHGA +AIRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRSEAGVVEYPDGGRYAVAVFTRA +ANATLPQADAAIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter sp. YR332 TaxID=1855298 RepID=A0A497YMY9_9SPHI +-sKLTAKLNDAVKDFHGQVGIYVRNLKTGKTA-EINADTLFPTASMIKVSIQCGVMDKIE +KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GS +EYINNWLDQNGFKVMRVNSRAPGREAMRKIYGWGVSTPREMCRLFTMIREGKAVSPAASE +RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH +NATPNNEAGLLIKKISALLWHYf +>[subseq from] Serine hydrolase n=1 Tax=Dyadobacter sediminis TaxID=1493691 RepID=A0A5R9KAC4_9BACT +-qKLTAMLEKALAGFHGNAGVYVRNLKTNQTA-AIHADSIFPTASMIKVPIMCGLFDKIS +KGEIRFNQELVYRDSLKYDNGIVGSFRDSTRIALPKVVHLMISQSDNTGSLWLQAMAGGG +AAINQWLDANGFANIRVNSRTPGRKEGQAKYGWGQTTPKEMAELVAMIRNGKAINAAASE +RMYRYLGMQFW-DGEAISQIPPYIKTAAKSGAVNQ-ARSEVLVVHAPHGD-YVFCVSTKN +QQQQNNEGYTLIRKVSEIIWNHf +>[subseq from] serine hydrolase n=1 Tax=unclassified Microbacterium TaxID=2609290 RepID=UPI00109CE46D +------DIQEIFTDAGATGFLHAREVEGGAEV-SVGADEPVVLASVFKILVLTAYVRAVA +AGELDPTERTTVTARYRIGGVGTAGFADDVVASWRDLALNMMTMSDNAATDVLYHRL-GT +EAVNRVISDLGLRQTRLIGCCEDLFAAVHPVKTSHSTPRDVTTLLNALWTDTAASAKACR +QAREIMALQVW-PHRLTSGFPPGVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA +ASL-ADRQPLVDASIGRAAF--- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Microgenomates bacterium TaxID=2093373 RepID=A0A3A4ZH15_9BACT +--QLLEQIKKSFETEKGSYSIYIYDLKSDSGF-GLNESAIFTAASVNKIYILAALYHQAD +QGKLDLDEDITIQSKDIQDGTGVIRYQGAGTYSLKTLAQLMIEKSDNTAAFVLTNII-GA +NTIQQLVNDWGFIQTDIDN--------------NKSSNKDVAGMFLKIYRGEVTDQAHTQ +EMIGFMDDSDF-ENRLPKDLPKNINVYHKIGSEV-GVIHDAGIVDLPEH-PYYIGVLTND +IS-DIEGTENKISEISKMVFDYf +>[subseq from] Beta-lactamase n=1 Tax=Kerstersia gyiorum TaxID=206506 RepID=A0A171KN27_9BURK +--RLAQGLAPILAGTQARVTMAVHALDGTPLF-EREAGTAMPSASLIKIPILMLLLEQVA +AGRWPLDHMLSLEHTERVGGTGILNQLPSVRLQLEELGRLMIVLSDNVATNALIDWL-GL +DDVTQWCQRAGLPQTRLERRMMDAQAR-AAGRDNWTSAADACAALLWLLRNGSLPAPLRQ +LGLQMLADQRE-QSHFGAALPAHAKLANKTGQLH-GLRHDAGILSAGG-QSVVLAVLADG +FTDP------------------- +>[subseq from] serine hydrolase n=1 Tax=Mucilaginibacter sp. HC2 TaxID=2714892 RepID=UPI00140AC5C2 +-rKLTQQLNDVVKGFHGQVGIYVQNLKTGKVA-AINADTLFPTASMIKVSIQCGLMDKIE +KGELQYNQKLVYRDSLLYKGEDILGSFKDKDIQLSKVALLMITMSDNTASTWLQKLV-GG +EYINNWLQQNGFKVMRVNSRVPGREAIRSIYGWGVSTPFEMCRLFTMIRQGKAVSAAASE +RMSRNMARIYW-DEKALSQLPPYVQTISKQGAVD-AAKSETVLVSAPHGD-YVFSIMTNH +NTDQDNEASVLIKKISALLWHYf +>[subseq from] Beta-lactamase class A n=1 Tax=Kerstersia gyiorum TaxID=206506 RepID=A0A4Q7MDH5_9BURK +--RLAQGLAPILAGTQARVTMAVHALDGTPLF-EREAGTAMPSASLIKIPILMLLLEQVA +AGRWPLDHMLSLEHTERVGGTGILNQLPSVRLQLEELGRLMIVLSDNVATNALIDWL-GL +DDVTQWCQRAGLPQTRLERRMMDAQAR-AAGRDNWTSAADACAALLWLLRNGSLPAPLRQ +LGLQMLADQRE-QSHFGAALPAHAKLANKTGQLH-GLRHDAGILSAGG-QSVVLAVLADG +FTDP------------------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces pactum TaxID=68249 RepID=A0A1S6JA18_9ACTN +------RLHAAFADAGVTGWLHAVDIDSGAQV-EAGADQPVCTASVHKVCVLVTLHELAA +AGVLDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL +DAVNRTTDRLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLSALWRDEACPPEYGA +AARRVMALQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT +AHAVLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=cyanobiont of Ornithocercus magnificus TaxID=2496102 RepID=A0A4Y3FT76_9CYAN +--TLSQRWRELASEEDLIASAFVLILDDGRYA-ELAPDVSLPAASSIKAPILATALELID +TGELQWHEPLVLNREVVAGGAGWMAKPLGTHFPAYEVVTEMIRVSDNTATNLLIQRIGGR +EALNNRFSVLGLDSTVVNNWLPDLEGT------NTTSARDLARSIALVETGEVLRPRSRD +LFRGVMETSVT-NTLLPMGLLQGYKIYNKTGDIGT-AYSDVGLIELPDGRRAVAAFIVKG +PFN-DPRSAELIRNFAAAM---- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0012B8DA80 +----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLALMIMVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNILRKSSCE +KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLITDIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis thailandensis TaxID=589330 RepID=A0A229S1V6_9PSEU +---IVERIEAVFAKAGARGFVHAREVGGGPEV-GVGADDPVVLASVFKIPVAVAFAREVA +AGRLDDTERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYYRV-GQ +EAVDKVLTDLGLTRTRLIGCCEDLFAVLDPERTTASTPREITELLDAIWTDRAGDPAACE +RVRAIMAQQIW-PHRISSGFPAGVTIAAKTGTLP-AVRNEAGVVTFVDGRRYAVAVFTRA +DSDRQPAIDSAIGEAASLAVEH- +>[subseq from] Beta-lactamase n=2 Tax=Clostridiales TaxID=186802 RepID=A0A084JR15_9FIRM +--TLEKRIEAEIKSYDGKMGIYLDDF-HGNVI-AIHADEAFETASSIKTYILACLFDEVE +KGNKSLDDIIEYKVEHAVDGSGVLAAEPGAKLRVKDAATFMIIVSDNIATNMMIDYL-GL +EKINQCIKALGCRDTVLHNPIHF-E---QYDRLGTSTPRDYASIFIRLAKGELISPRADE +MMLEILKKQHY-NSMITKDFPSFISVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE +FSDAAHPATVFGARVSRMILDQf +>[subseq from] Uncharacterized protein n=2 Tax=Rhodococcus TaxID=1827 RepID=X0Q6H5_9NOCA +-------------------------TEDGGDI-AVGADDLVVLASVYKLPLLVALCRAFE +SGELSPTATVRVNPADCTPPTGVSTFHDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL +ESVELALSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE +FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA +ARTDLPVVDAAIGHAARIAVT-- +>[subseq from] Beta-lactamase protein n=1 Tax=Heliobacterium modesticaldum (strain ATCC 51547 / Ice1) TaxID=498761 RepID=B0TAI9_HELMI +-dKLRQRIRKEMAESGIDYALFLEDLENGNQF-AIEPDKNFQAASAIKVPLVLFLYALAL +DKRLDLDETMTLTSSDLAPSSGGLWSYLPGRYTLRQLAKHVIEDSDNTAANMLMRRV-GR +SNFYLFLRLAGARTV------PAG----PG-KGNVTCARDMALYLKGIWVFRQLNPGFGE +EIFQYLLHSKI-DNRIPAGVPDDIKVANKIGSQI-GFFHDAAIVLLPNR-PYVLAILCHH +PSE--TEANAAIARISRIIYE-- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A352CHN3_9BACT +-kKLEARIENIVQGFKGEVGVYVKDLRSGRVS-TYHADTIFPTASIVKVPILLGITAAVQ +NGQLAYDSNHVYRDSLLYAGEDILGSFKDGEIALKKIIMLMMTTSDNTASLWLQSLAGGG +QRINALLKEQGLSSTFVNSRTVGREANRAQYGWGQTTPQEMGFLLEKIYRKEVFSSYASE +KMLRAMGRNFWDEDESIGCFPPYVEVFSKNGCVN-ASRSEAMIVNAPHR-PFVFCIFTKN +NQTHDNEAWSLARKMATMLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. ZH6 TaxID=2482727 RepID=A0A3E2NY34_9SPHI +-eKLTDKLKEAVAGFHGQAGIYVHNLKTGKTA-GINQDTLFPTASMIKVSILAGVMDKIE +HGELKYNQKLAYRDSLLYAGEDILGSFKDKDIMLSKVTMLMITMSDNTASLWLQKLV-TG +QHINNWLDSNGFKSMRVNSRVPGREAMQKRYGWGVTTPYEMCKLFTMIRDGQAVSRAASE +RMYRTLNRIYW-DEKALSQIPPYVQAISKQGAVDD-AKSETVLVNAPHGD-YVFSITTKN +NTTADNEASQLIKKISAMLWHYf +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus wratislaviensis TaxID=44752 RepID=A0A3D9R5H9_9NOCA +-------------------------TEDGGDI-AVGADDLVVLASVYKLPLLVALCRAFE +SGELSPTATVRVNPADCTPPTGVSTFHDPVVLSWRDLALSMMTVSDNAAADLVLGHV-GL +ESVELALSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE +FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA +ARTDLPVVDAAIGHAARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Crenotalea thermophila TaxID=1393122 RepID=A0A1I7NJX5_9BACT +-rKLQRKLEALVKPFQGTVGIYVHKLGTNKEA-AIHADSLFPTASMIKVAIQAVIFQRIA +DSQLQYHQNLLYRDSLYYPGVDILGMAKDSTIELSKVVMLMITESDNTAALWLQSLAGGG +TAINQWLADHGYQYYRVNSRTPGREAAYRQYGWGQTTPREMAQFLVQLRKGEIISPAASE +RMYRNLCHIYW-DDVALSQIPPYVQAASKQGAVDD-SRSEVVLVNAPHGD-YVFCVDTKD +IATHSNAAWELIRQVSALLWHYf +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 25 TaxID=1827542 RepID=A0A4R8H8K4_9ACTN +---TLRRIAAAFAEAGVSGRLHAVDIDSGTEI-DAGADHPVVTASVHKLCLLVALHQQAA +AGLLDLTEQVECPPADRAAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL +DAVNGATARLGLNRTRAVHTSRSLFAALDPARSNRSTPRDMTRLLTAVWRDEACTPEHGA +AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA +ASATLPAADAVIGTTARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2B2X0_STRVZ +haAARRRITTAFADAGVTGQLHAVDIDTGTAL-GVGSDTLVPTASVHKLCLVATLYRQSS +LGLVDPTRPVDIPAENRAPGATGLSAMRDAALSLRDLASLAVAVSDNTAADLLWDTL-GL +DTVNATMTGLGLTRTHAVQTMRELFAALDPTRTNRSTPREITALLTAVWRDEVCPGEYGE +ELRAVLGLQAW-SHRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA +ASTDLPAADAVIGGAARIAVD-- +>[subseq from] Beta-lactamase class A-like protein n=2 Tax=Sphaerobacter TaxID=2056 RepID=D1C8L0_SPHTD +--EFDRAAQRVVSRFSGELGFAAKNLTTGEEL-GINAECVLPTASVIKTAVLVELMRQAH +EEGLDLQERMTMTASDIVGGSGVLKELGPGLPTVADVAMLMIIVSDNTATNMLIDRVGGV +EAVNRTMQEYGLRSIVLHNRVDF--EVIGNDIRAEASAADLVRLHEMMARGELINAEACR +QMIDVLSRQQYLD-QVPRYFNQSFTVANKTGFFP-GTRVDSGLIMLHDGPTIAFAAMTHR +SV--------------------- +>[subseq from] Beta-lactamase class A n=2 Tax=Echinicola TaxID=390846 RepID=L0G2B4_ECHVK +-kKLTAALNSVFEGFKGTAGIYVEHLPSGKYA-AINADTIFPTASIVKIPILIGVFDKIE +KGELDYHEPLVYRDSIKYGGSGLMQYFEDSTTDLSTLLALMISYSDNTTSLWNQALAGGG +ETINPLMEQYGMVSTRVNSRTPGRDKDWEKYGWGQTTPREMATLLKKMRKGELISQAASE +RMYRLMTNVYY-DDYALSQIPPYVQTASKQGMVN-ASRSELVMVNAPHGD-YVLYIATKN +NEEPDNESWVLARKVSALLWNYf +>[subseq from] serine hydrolase n=1 Tax=Spirosoma spitsbergense TaxID=431554 RepID=UPI0003720A40 +-kKLEQKLKTAFASFRGDVGVYVHNLRTGKTV-AINADTLFPTASTVKIPIQCGLFDKIQ +QGELTYGQELVYKDSLHYDDGIVGSLKDGAKIPLSEVVMLMETVSDNTGSLWCQALAGGG +AAINDWLETNGFHQTRVNSRTPGRKANQAQYGWGQTSPRELASLLTYIRQGKAVSPAASD +EMYRNLGRQYWD-NDGLSQVPPDVKTACKNGAVNQ-ARSEVVLVHAPHGD-YVYCVMTKN +QKERTNEGFTLLRTVGAILWHHf +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus radiophilus TaxID=32062 RepID=A0A431VPS2_9DEIO +------------SGFGGTVGLLIQD-ETGHEIcSLNADRVFPAASLIKVPLLILGLQAVQ +RGGLALEDRLPLPAAEQVPGAGVLHELGPGLLSWQDLLTLMIIVSDNTATNVVIDCL-RL +SAVQAALPGLGLAHTRLVGKLERYNAAQRRGERNQTTPRDMLRLLQRLRRGEYLDPVHTA +LALDILGRQQL-RDLIGRRVPCGYRVLSKSGELT-GVHHDVGWLLTP--RPLAVACLSQG +GEDAR------------------ +>[subseq from] serine hydrolase n=1 Tax=Spirosoma luteum TaxID=431553 RepID=UPI00036D5048 +-kKLEQKLQTAFANFRGDVGVYVHNLRTGKTV-AINADTLFPTASTIKIPIQCGLFDKIQ +QGELKYGQELIYKDSLHYDDGIVGSLKDGSKIPLSEVVMLMETVSDNTGSLWCQALAGGG +SSINDWLETNGFHQTRVNSRTPGRKANQAQYGWGQTTPRELANLLTYIRQGKAVSVAASD +EMYRNLGRQYWD-NDGLSQVPPDVKTACKNGAVNQ-SRSEVVLVHAPHGD-YVYCVMTKN +QKERANEGFALLRAVGAVLWHHf +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. GLM-1 TaxID=2267691 RepID=UPI00131515F0 +------RIADAFLAAGARGFLHAKEIGGGGEV-AVGADDPVVLASVFKIPVAVAYAREVV +AGRLDETERTRVGKRYRIGGIGTAGCADDVEMSWRDLALFMLTMSDNAATDVLYHRV-GQ +AAVDRVLADLGLGRTRLIGCCEDLFAVLDPERTTASTPREITTLLEAIWTDRAAEPAACE +RVRAIMARQIW-PHRISSGFGSDVKIAAKTGTLP-AVRNEAGVLSFPDGRRFAVAVFTRA +DSERQPAVDAAIGKAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura chibensis TaxID=392828 RepID=A0A5D0NPJ0_9ACTN +----NERIEDEFGAAGVAGWLHAVDVDTGREV-SVGADEPVVLASVFKVPLLVAFHRQAA +SGLLDPSEQVTLRPEDRTAPTGVSGMLDEVRMSLRDLTFLMITVSDNAAADVVLDRV-GR +GAVNATAEALGLPGTVVEVSGRELHEVLDPLRTSRSTPRDMTRLLSLIWRDEAAPAEGCA +AMRRVFGLQVW-PHRLSSGFPDDVLVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +LLAVLPQADAVIGTAARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. GEYO TaxID=2575511 RepID=UPI000E0E872A +---LSERWQTLAAEQDLKVSAFMLVLDDGRYA-QLEPDTALPAASSIKTPILLVTLEELD +AGRLSWNEPLQLSKTVVGGGAGWMAKPLGTRFPTHEVATEMIRVSDNTATNLLIERLGGQ +EALNARFNALGLSATKVNDWLPDLKGT------NSTSARDLARSIALVDTGEALSIRSRD +LFREVMGTSIT-NTLLPRGLLHGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG +PFND-PRSTELIRKLAAAM---- +>[subseq from] serine hydrolase n=1 Tax=Achromobacter sp. 2789STDY5608607 TaxID=1806497 RepID=UPI0006C8C148 +-qHVDAALAPLLAATPARVSLSLRDLDGGIVL-AHHADRVQPSASIIKVPILLALLEAVA +KGRYALEQPLALPASERAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIELL-GF +DEINQWNQRAGLPASRLQRRMMDAAA-REAGRDNFTSAEDATASLCWMLRDGALPAALRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FT--------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus koreensis TaxID=99653 RepID=A0A1H5CIZ0_9NOCA +----------------------------AGDI-AVGADDVVVLASVYKLPLLVALCRAFE +SGELSPTATVRVNPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGRV-GL +ESVERSLSDLGLTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGAQGE +FVRQVMSAQIW-QHRIRSGFPSGVDVAGKTGTIG-AIRNEVAVVTFPGEIPVAVAVFTRA +ARTDLPVVDAAIGHVARIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI000412EF4F +----AAAIEAVFANAGARGFVHAKEIGGGPEV-GVGADDPVVLASVFKIPVAVAFAREAA +AGRLDDTERVRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVIYHRV-GQ +DAVDRVLTDLGLERTRLIGCCEDLFAVVDPERTTSSTPREITTLLDAIWTDRAGDPAACE +RVRTIMAQQIW-PHRISSGFPAEVAIAAKTGTLPS-VRNEAGVVTHVDGRRYAVAVFTRA +ESDRLPAVDSAIGEAARLAVEH- +>[subseq from] Beta-lactamase class A n=1 Tax=Nocardia mexicana TaxID=279262 RepID=A0A370H2E9_9NOCA +-------IRAVFADAGCTGWLHARRCGDAAEI-SVGGRSRVVMASVYKLPLVVAFCRGVD +AGLIDPTAHLTVRPSDCTPPTGIAALHDPVTLSRRDLATSMMTVSDSAAADVLLGEI-GL +AAVEELLGEIGLTETQVVGGTADQLRAYDPAFASATTPEEMTRFLCAVWSGGVLSAGQTD +FVKSVMRRQIW-PHRVAAAFPRRVSVAGKTGTIG-AIRNEVAVVEFPDEYPVAVAVFTRA +ARADLPVADAAITEAARIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI00064E8DFF +----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIRRMEKNTVGGAGVLRALPRLTIKVEELLALMIMVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE +KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLITDIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006BF1D9A +-qHVDAALAPLLAATPARVSLSLRDLDGGTVL-AHHADRVQPSASIIKVPILLALLEAVA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] serine hydrolase n=1 Tax=Desulfallas alcoholivorax TaxID=265477 RepID=UPI00040F545A +---LDQSVSEYLSDQKGTYGLYFIDLKSGKEF-GYNQYTPFHAASTFKLPMNLYLYTQAE +KENINLDQKLTSQSHHMEGGTGFLKNYPPGKYTIKQLATYSIVNSDNIATNILLERL-GR +EKVKSYMRSLGGKVV--------------VDGKNVTCPYDLALYMQKTIEFYRTDSPEAK +MLMENLINSEF-KDRIPAALPPNTKVANKIGNWPTNTYNDVAYVNHPVR-PYILAVTCSD +TP-GYGTAVPVIRQVSKMIYEY- +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora antimicrobica TaxID=455193 RepID=A0A1I5KE73_9PSEU +---VERRIREVLADAGAEGWVHATQFGGGREI-CVGADELVVTASVYKLPLLVAMCRAFD +AGRLDPRATVRIDPTSCTPPSGFSTFLDPVTVSWRDLAASMIAVSDNSAADVILGAV-GL +DAVADVLDDLGLTRTRVVGGTADQHAAYDPAYAGATTPREMTRLLELIWTDAVASPQQCA +FIRRLLGNQIW-MHRVRSGFPQGVRVAGKTGTIG-AVRNEVSVVEFEGEEPVAVAVFTLA +ARADLPRVDTAIGECA------- +>[subseq from] serine hydrolase n=1 Tax=Acidobacterium sp. S8 TaxID=1641854 RepID=UPI00131C0E37 +--TLEAQLQAIAQTHHGHVTLFAHDLKSGKTA-AMNADTPAPTASVIKLTVLFEALKQIQ +EGKAHFDDRLTLTKENQVEGSGVFMFFDTPQFTLKDVLTMMVIVSDNTATNLAIDHL-GL +KNIDDRIQWLGLKNTWLYKKVSLMPADQKQFGLGKTTAREMAEVMERFATGNVAKPTADE +KLCDHMLKNQFYRNSIPRYLEGESKIANKTGALDK-VRNDVGVVFAKNG-PVIISMFTYE +NETPDNQAEVLMAKLAHTIVDRw +>[subseq from] serine hydrolase n=1 Tax=Deinococcus deserti TaxID=310783 RepID=UPI000A03E980 +-----------QRGFAGDTGLRICDLDGTELY-ALNATRTFPAASTIKVPLLIQALQEAQ +TGRLNLRERVTLEAADRVPGSGILYELGAGLPSWLDLLTLMVIVSDNTATNLVIARL-GP +DEINSWLARGGWSSTRLIGRLEQQNEAQRRGERNRTSAHDQVDLLLRLANGALLDRTHTD +LALSILSRQQL-RDIIGRRVPRSYRLVSKSGELT-GVHHDVGILYTP--RPLVIALLSEA +GQREHPENRDVL----------- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. ACS1 TaxID=2028570 RepID=A0A2A3F7A9_9NOCA +-----------------------------GDI-AVGADDVVVLASVYKLPLLVALCRAFE +SGELSPTATVRVNPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGRV-GL +ESVERSLSDLGLTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGAQGE +FVRQVMSAQIW-QHRIRSGFPSGVDVAGKTGTIG-AIRNEVAVVTFPGEIPVAVAVFTRA +ARTDLPVVDAAIGHVARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-1521 TaxID=1609100 RepID=A0A0X3X4Q3_9ACTN +--DVQRAIRGMFADAGVRGWLHVAELHREARV-TVDPDEPVPVGSVYKVPLMAAFCRLAD +AGALDPRQPVTLGPDERMPRTGISILRDPITVSLRDLVVLMMSVSDNTSADAVLRHV-GP +AAVEELCRDLGLPDTHILGGAATTFEVYNPLSKASSTPSDMARLLRAIWTDGAASAESCA +FMRETMGQQAW-SHRLASGFPDDVTVSGKTGTFGT-MRHEAGVVELPDGGVYTAVVFTQA +ARADLPRADAVIGTAARAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000532B730 +---------------RSNNGLIRIHIEGKESI-QINSFIKQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIMVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE +KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLITDIGYL----- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SLF1_9BACT +-sELENRIDSLLNCKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD +KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI +KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKE-- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Bacillus TaxID=1386 RepID=UPI00064ACABB +---------------RSNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIMVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE +KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLITDIGYL----- +>[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1K1PYC6_SELRU +---------QVIGANNKQLAVYFLRPGREVEP-FIYNQRRMFPASMIKLFVMAKTMQDVH +DGRLSLEEQLTIRKQDVVGGAGVTTWYNAGERTVAQLIQLMVVESDNTATNMLIDKL-GM +ANINQYLQQYGYKDTLLVHKLMVNKKA---SNKNLSSVRDIGHLLTNLYYHQLVGEKEDA +FMLDILKQQRD-KECFPAVVS-GYDIAHKTGEVN-GVYADGGIFYGPQED-FILVALSNS +NE--------------------- +>[subseq from] Serine hydrolase n=2 Tax=Acetobacter persici TaxID=1076596 RepID=A0A1U9LI62_9PROT +---LAQRMAETVANQPGHYAVYAARSGQAPDV-CLNCDDLINAASTIKLFVLDAAYAAFA +KGTLHPDDTLTVHNRSLVGKGHFTYAQVGKAVPVSELLRLMIQYSSNLATNLMIEKL-GV +LPIRSVVNAQGLNGIIFGRMIEDFDAD-AQGIRNRVSARGLGSFLQKLNNGQIVGKTQSQ +SMIRIMLGQKF-NDIIPPGLPAGTPVAHKTGWVN-GVRNDAAIVTLPDGRQYILVVLTSG +LP-DEQAGIKVLNTLSHQAYLYf +>[subseq from] Serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A5Q0D5M4_BACME +----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLALMIMVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMD-ETAVKQGSDNYTCASDVVKCLKEICEGNFLRKSSCE +KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLITDIGYL----- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter tropicalis NBRC 101654 TaxID=749388 RepID=F7VDT5_9PROT +---LAQSISRTVKAQPGHFAVYAALSGHSPAV-CLNCDDLINAASTIKLFVLDAAYDAFT +KGTLHPQDTVTIHNRSLV-GSGTFYAQAGKPVPVSELLRVMIQYSSNLATNLMVEKL-GV +MPIRSLVKAQGLDGIVFGRMIEDFDAN-DKGIRNQVSARGLGAFLQKLDNGQIVGKAQSQ +SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGKHYILVVLTSD +LP-DEQAGIKVLNTLSHQTYTYf +>[subseq from] class A beta-lactamase n=1 Tax=Kineococcus sp. T13 TaxID=2696565 RepID=UPI00141200B6 +---------------------WALDLRTGARL-AHRADVPRPLLCLHAGLVAARLLRTGG +--PAVLRRHLRFSPDDLVDGSPVCCWHLSDGMSVEQLCDAALRRADATAANLLLGLVGGP +RGFTRSCRELGDRTTRLDRWAPESSGGQPWEPRDVTTATALARGYGRVLVGTALPAPARA +QLRSWLAT---------APLPGGWCFTHAAGTGWYGSAAVVGLAQRGAR-TVLVSVLTRS +GQPSTRGSARTARAAAA------ +>[subseq from] Beta-lactamase class A n=2 Tax=Rhizobiales bacterium GAS191 TaxID=1882830 RepID=A0A1H4W700_9RHIZ +---ASDIVAALRDRDGIDVGFSAIHLASEQCL-EINASSLFPTASVFKVPVMVEVFRQAR +AGIFAMSDRLTLATCHKTLTSGVLVTLDDGLPTIGDLVMLMTIVSDNTATKLLLDLV-GM +DKVNAAMAGYGLHDIHVAIDVHEMFLTFSRERDNTASAADMARLMAMIAAGEVVDAEACG +SMVAIMKEQQY-SERVPRYLPFG-SVANKTGTMR-GVRNDSGIMRRGEGDDIAYTVFTFD +PTPLAAGNSRFLAE--------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNQ766 TaxID=1169157 RepID=UPI00037C0795 +hrTARSRIRRAFTEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE +HGRIDLTTVVDIPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI +EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA +DLRRTLGAQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia sp. ET3-3 TaxID=2675851 RepID=UPI0012FC1F48 +---------EIFRTAGVEGRVHARCFDCDGEF-GWGADEPVVLSSVMKVPLVLEFARQVA +AGQLDATDRVRATAADRLGGVGTAGCLDDVEYSLRDAAYFAITVSDNTAADLLFDRV-GV +ENVRSLVRELGLVNTRIVGSLRDILYAVDPLRTTASTPREMTRLLQLIGEDRAGLPEACE +WVRDLMRRQVF-GHRLPSGFPPGTDIWSKTGTLP-GIRNEIGVVGYPDGSRYAVAVFTVS +QSGRQPAVDRAIGEAARQAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter frigoritolerans TaxID=652788 RepID=A0A562UGU1_9SPHI +-kKLTVKLQEAIKGFDGQVGIYVQNLKTGKTV-TINADTLFPTASMIKVSIQCGLMDKIE +KGEIQYNQKLVYRDSLLYKGEDILGSFKDGDIEVSKVAMLMITMSDNTASLWLQKLV-GG +EYINNWLDQNGFKVMRVNSRVLGREAIRAKYGWGVTTPYEMCRLFTMIRQGKAVSAAASE +RMSRNMGRIFW-DNKALSQIPPYIQTISKQGAVD-ASKSETVLVNAPHGG-YVFSIITNN +NKTTDNEADILIRKISALLWHYy +>[subseq from] serine hydrolase n=1 Tax=Emticicia sp. ODNR4P TaxID=2683257 RepID=UPI00141305B8 +-kTLEKKLQVLVKDFQGVAGIYVKHLKKNTGV-AIQADTIFPTASMIKVPITIGLFNKIE +KGELDYHAILTYKDSLLYAGEDILGSFKDGEIALSKVAMLMITTSDNTASLWCQAMATG- +TAINEWLAANGFENTRVNSRTAGREAYRKLYGWGQTTPREMAELLVKIKKGEVISPAASE +RIYRNMVRIYW-DGEALSQIPPTVQVASKQGAVNQ-SRSEVFLVNAPSGD-YVVCVTTKN +QKDENNEGYQLLRNVSKIVWEHy +>[subseq from] Serine hydrolase n=1 Tax=Flectobacillus sp. BAB-3569 TaxID=1509483 RepID=A0A267TIN9_9BACT +-kALEKKLQMLVKDFQGVAGIYVKHLKKNTGV-AIQADTIFPTASMIKVPITIGLFNKIE +KGELDYHAILTYKDSLLYAGEDILGSFKDGEIALSKVAMLMITTSDNTASLWCQAMATG- +TAINEWLAANGFENTRVNSRTAGRESYRKIYGWGQTTPREMAELLVKIRKGEVISPAASE +RIYRNMVRIYW-DGEALSQIPPTIQVASKQGAVNQ-SRSEVFLVNAPSGD-YVVCVTTKN +QKDENNEGYQLLRNVSKIVWEHy +>[subseq from] Serine hydrolase n=1 Tax=Kibdelosporangium aridum TaxID=2030 RepID=A0A428Z679_KIBAR +-----QRIRAVFQDAGTAGWLHAMPLGASREV-DVNADEPVVMASVYKLPLLVALCRQFD +AGRIDPLSTIRINPASCSPPTGIATFLDPITMSWRDLAASMMTVSDNAAADLILGEV-GL +DTVGKTLADLELTGTKIVGGAADVEAAYDPAYTSATTPRDMTRLLSLIWSDSVASAEQCA +FIRQLMGKQVW-LHRIRSGFPGDVRVSGKTGTIG-AVRNEVAVVEYAHETPIAVAIFTFA +ARSDLPAVDAAIGEAARIAV--- +>[subseq from] serine hydrolase n=1 Tax=Microbacterium wangchenii TaxID=2541726 RepID=UPI0011C703DD +------------TAAGVDLGVAIEDLSDGRSL-FAGKQDRSTTASTIKMALAVTVMQQVE +DGMLTLDDIRTILPEERYEGSGVLKDGPFPQVSIGRMLDLMITVSDNTATNKLVDVVGGF +GPINATIEAAGIPRTDLHFGRKMFGGIVPPDGDLWLTPSGMNELLTRIYEAAFLSAASAE +HIIDLMLAQQV-KTKLGATVPAGV-LAHKTGENAE-VSHDVGLVLIPGQ-EITLSVFSTV +RPDVQAVANPFLQRIGTAVHD-- +>[subseq from] Beta-lactamase TEM-12 n=1 Tax=Synechococcus sp. MIT S9504 TaxID=1801628 RepID=A0A163Y7H8_9SYNE +---LSERWQTLAAEQDLKVSAFMLVLDDGRYA-QLEPDTALPAASSIKTPILLVTLEELD +AGRLSWNEPLQLNKTVVGGGAGWMAKPLGTRFPTHEVATEMIRVSDNTATNLLIERLGGQ +EKLNARFNALGLSATKVNDWLPDLKGT------NSTSARDLARSIALVDTGEALSIRSRD +LFREVMGTSIT-NTLLPRGLMRGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG +PFND-PRSTELIRKLAAAM---- +>[subseq from] Serine hydrolase n=1 Tax=Flavihumibacter sp. R14 TaxID=2705549 RepID=A0A6B3PLK7_9BACT +-kNLTGRLHDLVKGFQGEAGIYVKNLKTGKTA-FVNADTLFPTASMVKIPIMVGVFDEIE +KGNLNYNAELIYRDSLLYEGEDIIGSFKDGEIRLSKVQMLSITTSDNTGSLWLQKLV-GG +EKINNILQSMDFKHTRVNSRTPGRRPNWEVYGWGQTTPREMATLVEMIREGKVISPAASE +RMYRNLIRIYY-DGQALSQIPPYIQVASKSGAVDE-ARSEVVLVNAPHGD-YVFCITTKN +QKNQQNEGFRLIRNLSALLWNYf +>[subseq from] Beta-lactamase class A n=1 Tax=Dinghuibacter silviterrae TaxID=1539049 RepID=A0A4R8DI35_9BACT +-rRLQKRVDSLTQGFHGDVGIYIYDPGRDRYA-ACQPDALFPTASIVKISILLGIMDKIR +TGALDYHQRLTYTDSLFFKGDDILSDFTPGSIELSKVMMLMLTISDNCASVWLQGLAGGG +TRINALLDSLGFSKTRVNSHTPGRSADWERYGWGQTTPREIVHIMDRIVRGEVFDPKSSA +MMLRLLGRQYW-DEEALSQIPAGVFAADKNGALDS-SRNEV--VYVHGRHPYIFSIFTKN +NTTQDNEAWALTRRLSALLWTYy +>[subseq from] Serine hydrolase n=1 Tax=Kitasatospora xanthocidica TaxID=83382 RepID=A0A372ZLK2_9ACTN +--AARTRIAAAFADAGVTGRLHARDLDTGAEI-GLGADTAVSTASVHKLCLLVTLYREAA +AGRIDLTRQVDVPAAGRTPGSIGLGAMLDDALSLRDLAYLTAAVSDNTAADTLWDRI-GL +DTVNRTMADLGLTRTVAVHKLRDLIAVLDPAFTNHSTPRDMTTLLAALWHGDACPGDHGT +ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA +AATTLPAADAAIGTAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Epidermidibacterium keratini TaxID=1891644 RepID=UPI0013194E72 +-------IMEVFIDAGIEGAVHALDLDSGATV-EYAADRQFAMASLYKLPLLVALCRRFE +RGELDPTEAVTSRRDERTAPTGLSLLRDAVTMSLRDHAVSMISVSDNAAADILFARV-GH +DEIGRVLREAGCESTQVVGGTAETHAAYEPRLLGPTTARDQTRLLAAIWTGTLIGDAQGA +FVREALGSQVW-THRIRSGFPRGVRVNGKTGTLG-ALRHESAVVQYPNEPAYAVSVLTRA +ARADLPAADRAIGRAARVAVS-- +>[subseq from] serine hydrolase n=1 Tax=Peptostreptococcaceae bacterium TaxID=1904861 RepID=UPI0011DD730C +------KIISRLKDMEGDISFYYKNLVTQETI-KYNEEKEMLAASLIKLTVLVECFSQIK +QKVISKDEIFITKERDKVPSCGALNYMRENLVTLEDLYVLMIILSDNYATNILIDKL-GI +DNINMTIKDIGLKNTIINRKMFDSEKA-KLGLENYTSAKDMGDLLEMMYNKDLVDEKSSE +EMISILKNQRL-NGKIPQGVKPKVSIAHKTGEDTN-ITHDVGIVFAKDP--FIVCF-CGN +NV-NVPEYERLMQDITYDIY--- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A537KLW1_9BACT +-kKLRAMISSTIKQYNGEIGIYVKNLKSKRIV-AVNADTVFPTASIVKVPILIGVMDKTN +HGELFYDSSLTYKDSLLYEGEDILGSFKNNEILLKKIIMLMLTTSDNTASLWLQSLAGKG +TRINEILDSLHFKYTRVNSRTPGRESNRTIYGWGQTTPSEMGRLFEMIYYGQIFSPPVCE +RMMRCLGRNYWDENEAISQIPPTIEVFSKNGCVD-ASRSEVMLVNAPHN-PYVFCIFTKN +NKTHTNEAWTLARKISKLLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. EAC657 TaxID=2024881 RepID=A0A2D8TW03_9SYNE +--ALSQRWKELAAQADLKVSAFMLVLDDGRYA-QLEPDTALPAASSIKTPILLVTLEELD +AGRLVWNEPLTLTKTVVGGGAGWMASPIGTRFPTHEVATEMIRVSDNTATNLLIDRLGGK +EALNLRFNALGLSATTVNNWLPDLEGT------NTTSARDLAYSIALVDTGEALSIRSRD +LFRQVMGTSIT-NTLIPRGLMRGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG +PFND-PRSTEMIRKLTAAM---- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. CB0101 TaxID=232348 RepID=A0A4V1DI92_9SYNE +--AVSQKWAQLAARHDLQASGYLLVLDDGRFA-QLQPDRAMPAASSIKTPILLAGLEELD +AGKLRWNEPLALTKEVIGGGAGWMAKPVGTRFPFWEAATEMIRVSDNSATNLLIKRLGGK +VALNARFQAMGLTATVVNNWLPDLDGT------NTTSSLDLARSIALVDTGEMLSPRARD +LFRGVMGTSRT-NTLLPLGLLKGVTVLNKTGDIGI-AYADGGLIELPNGQRAVAAFMVKG +PFND-PRSTELIRAMAAEVA--- +>[subseq from] Serine hydrolase n=2 Tax=Candidatus Cryosericum terrychapinii TaxID=2290919 RepID=A0A398D6W6_9BACT +-qDWQKQVRALLGNAQGEFGVYAA-TPSVSLF-EYQTSSIFPSASTIKVLIMAELLRQVE +AGTHALTEHP-VLPTAPTGGCGILEFLSSDYPDLMDLLHFMICSSDNKATNVLIRLT-GM +DAVNQLAVDIGMTNTRLRRFMMDTES-IQQDIDNTTSPADMGRFFKLLACNELVSSKASA +TMKTILSHQQF-ADIMMLFLPEGIRAEHKTGGFP-GSVLDVGLVYGA-RDPLILCLMATQ +LAN-NGEGAIILGKVAAIAYT-- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. BN140078 TaxID=2607653 RepID=A0A5B2VY16_9BACT +--RLAALLRPLLAQHHGVAGIYVHHLKKDRYV-AINADTVFPTASTIKIPIMIGVFDKIA +NGELQYHQQLIYKDSLLYEEEDLLGSFKSGQLELAKVMMLMLTMSDNTASLWLQSLAGGG +LRINTWLEAHGFVNTRMNSRTPGREVNRSQYGWGQTSPREMARLMEMIYKGEVVSKTASE +RMYRNLTRNYW-DTEGLLQIPPYIRTASKNGAVD-ASRSEVIMVNAPHGD-YVYSIITKN +NQERNNEAWNLLRSVAGVIWNYy +>[subseq from] serine hydrolase n=1 Tax=Emergencia sp. 1XD21-50 TaxID=2304570 RepID=UPI001379D0FF +------KILQELAAMPGKVGFYYKNVVTGETL-GYNQQESFLPASVVKLPLMMAILLFRS +RGETDFDERITIRDDQKVPGCGAVQHIPGEVLEMGALAKMMITISDNTATNALLRHY-TV +PKVREAFHELGMIGTQFNREYYDYESE-NKGIQNYFVPEELGILLEKMYRRTLINEEASI +WLENVLRQQQI-NHKMGGYLPMDYPMAHKTGEEED-KTHDVGIVFAK--QPFIVCYASND +IE--IAVFEDFIRRTTKALAD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter gossypiicola TaxID=551995 RepID=A0A1H8SEC6_9SPHI +-sKLTAKLNDAVKDFHGQVGIYVHNLKTGKTA-EINADTLFPTASMIKVSIQCGVMDKIE +KGELKYNQKLGYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GS +EYINNWLDQNGFKVMRVNSRAPGREAMRKIYGWGVSTPREMCRLFTMIREGKAVSPAASE +RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH +NTTPNNEAGLLIKKISALLWHYf +>[subseq from] Uncharacterized protein n=2 Tax=Lactobacillus harbinensis TaxID=304207 RepID=A0A510U2V6_9LACO +--EVQAAVNQTMGQIPGDNSVFVSASDELHLKhFVQNNRPQRAASIIKIFIMVTAFAKAQ +NGDLNLADTYTVAGADKVSGTGDMQNMPDGTLSYRQVMDHMMEKSDNMAANVMIAYLGGL +DVVNQEIKKLGFPDTVLERKMMDTD-ALAAGKDNMTSVQDLGDALTLINNGKLISKEADN +QMMAIMKNNQN-HEKLPAKITNATAIYNKTGEFQYGVENDAAIVQGDQH-VFVAVVMSQN +GHE-------------------- +>[subseq from] DZANK-type domain-containing protein n=1 Tax=Lactobacillus harbinensis TaxID=304207 RepID=A0A5P2TUF4_9LACO +--EVQAAVNQTMGQIPGDNSVFVSASDELHLKhFVQNNRPQRAASIIKIFIMVTAFAKAQ +NGDLNLADTYTVAGADKVSGTGDMQNMPDGTLSYRQVMDHMMEKSDNMAANVMIDYLGGL +DVVNQEIKKLGFPDTVLERKMMDTD-ALAAGKDNMTSVQDLGDALTLINNGKLISKEADN +QMMAIMKNNQN-HEKLPAKITNATAIYNKTGEFQYGVENDAAIVQGDRH-VFVAVVMSQN +GHE-------------------- +>[subseq from] serine hydrolase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI000BEF7D39 +----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLALMIMVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE +KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLITDIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=A0A317TIQ5_CLOPF +------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE +EGIIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM +DKINKTIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ +MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG +IPNS-VYGTVTLAKSGKMTWD-- +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. HYN0043 TaxID=2305508 RepID=A0A494W7W7_9SPHI +-nKLAVKLQDVVKGFHGQVGIYVQNLKTGKTV-EINADTLFPTASMIKVSIQCGVMDKIE +KGELQYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GG +QYINNWLDQNGFKVMRVNSRVAGREAVRKIYGWGVSTPREMCRLFTMIREGKAVSAAASE +RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSVITNH +NTTPNNEAGLLIKKVSALLWHYf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces vinaceus TaxID=1960 RepID=A0A5J6J0U3_STRVI +---TLRRIAAAFAEAGVSGRLHAVDIDSAAEI-DAGADHPVVTASVHKLCLLVALHQHAA +AGLLDLTEQVECPPGERTPGPTGLAAMLDPVMSLRDAAYLMMAVSDNAAADLLLARV-GL +DAVNEATARLGLTRTRAVHTFRSLFAALDPARGNRSTPRDMTRLLTAVWRDEAACTPEHG +AAIRRLLGLQVWPHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA +ASATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Olivibacter sitiensis TaxID=376470 RepID=UPI0003FD9D97 +-kKLQSKLEQLCEGYEGTVGIYVYNLKTGKEA-AINADTIFPTASIVKVPILVGLFDKIA +KGDLSYHQPLLYRDSIKYGGSGLMQFFQDSVTDLSTLAALMISYSDNTTSLWCQALAGGG +ATINALMESYGLQATRVNSRTSGREDIWKIYGWGQTSPREMAQLLVKIRKGEIIDQAACE +RMYRLMSHIYY-DDYALSQIPPYIQTASKQGMVND-SRSELVMVNAPHGD-YVFYIATKD +NKDKDNAAWQLTRNLSALLWQYf +>[subseq from] serine hydrolase n=1 Tax=Microbacterium oxydans TaxID=82380 RepID=UPI000B8648B7 +------SIAEIFADAGATGFLHAREIGGGPEV-SVDADEPVVLASVFKILVLTAYVRAVA +AGELDPTERTTVTARYRIGGVGTAGFSDDVEASWRDLAQNMMTMSDNAATDVVYHRL-GS +DAVNRVISDLGLRQTRLVGCCEDLFAAVHPIKTSHSTPRDVTTLLDALWTDTAAPAEACR +QARDIMAQQIW-PHRLSSGFPSGVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA +ASERQPLVDASIGR--------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2CC25_STRVZ +--------------AGVTGRLHAVDIDTGADV-DFGADQPVVTASVHKLCLLVTLHQRAA +AGALDLTEQVECPADLRTPGPTGLSAMLDPVMSLRDIAFLMMAVSDNTAADLLLARV-GL +DAVNATTAALGLDRTHATHTFGELLAALDPARGNHSTPRDMTRLLAAVWRDEACAPPHGP +ALRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA +ASAILPAADAVIGTASRIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. SC4 TaxID=1793160 RepID=A0A135H494_9NOCA +-------------------------IDDGGDI-AVGADDLVVLASVYKLPLLVALCRAFE +SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLAMSMMTVSDNAAADLVLGQV-GL +ESAERALSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE +FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA +ARTDLPVVDAAIGHAARIAVT-- +>[subseq from] Serine hydrolase n=4 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A6B2USB4_9ACTN +---ARHRIRDLFADAGVRGWLHVAELRRPAACvTVDPDEPVPVGSVYKVPLMVAFCRLTD +SGAIDPRQRVTLGAADRIPPTGVSLLQDEVTMSLRDLVVLMMTISDNTAAHVVQRWV-GT +TAVEAVCQSLGMPDTHIRGGAATTFEVYNPLRKASSTPADMARMLRAIWTDRAASAAGCA +FMRDVMGRQPW-SHRLASGFPDDVTVSGKTGTFGS-MRHEVGVVELADGSAYTAVVFTQA +ARADLPRADAVIGAAARTAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Microgenomates group bacterium GW2011_GWC1_49_7 TaxID=1618530 RepID=A0A0G1VW95_9BACT +--TLKQKIQEAVANQWNNYSVYVVDYNAPFTV-GINETVIYDAASVNKIPILAALYVKAQ +NGEVDFDKTITPQPDDIQDTGSIRYDPPGTAYSIKTLARLMMQKSDNTAAYVLANHVVGL +NKIQTLANGWGLTQTDM--------------IKNTTTNRDMEILMKKIYDGKIVGTALTA +EMLAFLKDSDF-ENRLPALLPQDSTVYHKIGTID-GGVHDVGIVERGKT-RYYIGVFTDG +VA-DVEAAEKLIAKVSRMVFDY- +>[subseq from] serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=UPI000D718B1C +------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE +EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM +DKINETIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLGKENSQ +MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG +IPNS-VYGTVTLAKSGKMTWD-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured Bacteroides sp. TaxID=162156 RepID=A0A3G2C899_9BACE +---LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD +NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV +AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS +FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSA--------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Pedobacter nototheniae TaxID=2488994 RepID=UPI00103895DA +-rKLQQKLDELVKGFNGEVGIYVKNLKTGKVA-SVNADTIFPTASMVKVPISCGIFNKIE +KGELDYHARLTYCDSLLYAGEDILGSFKDGEIELGKVLMLMITTSDNTASLWSQLMAGTG +TAINEVMASNGLQFTRVNSRTPGRREHQQKYGWGQTTPREMATLLTLIRDGKMINSAASE +RIYRNLIRIYW-DTEALSQIPPTVQVASKSGAVD-AARSEVLLVNAPHGD-YVFCITTKN +QKDTSNEGWTLIRNLSKTLWNYy +>[subseq from] DZANK-type domain-containing protein n=1 Tax=Lactobacillus harbinensis TaxID=304207 RepID=A0A5P8M8J7_9LACO +--EVQAAVNQTMGQIPGDNSVFVSASDELHLKhFVQNNRPQRAASIIKIFIMVTAFAKAQ +NGDLNLADTYTIAGADKVSGTGDMQNMPDGTLSYRQVMDHMMEKSDNMAANVMIDYLGGL +DVVNQEIKKLGFPDTVLERKMMDTD-ALAAGKDNMTSVQDLGDALTLINNGKLISKEADN +QMMTIMKNNQN-HEKLPAKITNATAIYNKTGEFQYGVENDAAIVQGDRH-VFVAVVMSQN +GHE-------------------- +>[subseq from] Beta-lactamase family protein n=1 Tax=Synechococcus sp. (strain WH8103) TaxID=29410 RepID=A0A0H5PR08_SYNPZ +------RWRTIATQKDLQTSAYMLILDDGRFA-QMHADRPMPAASSIKTPILLAALQQVD +AGDLHWNEPLVLTKELVGGGAGWMASRPLGSFPTRVAATEMIRVSDNSATNLLIERVGGQ +QTINQRFDDLGLTATEVNNWLPDLDGT------NTTSAHDLSRSIALVDTGEALSLRSRD +LFREVMGSSVT-NTLLPTGLMQGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG +PFND-PRSTNLIRALAAAMA--- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus subterraneus TaxID=285983 RepID=A0A427TK48_9BACI +-------------RCKGRASLFMEI--NGEII-EFNSNHVYQSASLIKLPILYAALRLVD +KGVLSLKKLVPIRETDEVGDTGVLQVLMVDQLSVQDLLALMIIVSDNTATNLVIDEI-GM +GEINSKIALLGMDQTVLKRKMLDFN-AIKNGNDNFTTARDTVACLKEGTAGSTLTNHSKG +IFQTLLKQQQL-KDKLRACLDPRIEAGNKTGELP-GVEHDCGFIFDEKT-QIHVAILIDQ +LN-DPEAGRTTIRQIGKHI---- +>[subseq from] serine hydrolase n=1 Tax=Sporotomaculum syntrophicum TaxID=182264 RepID=UPI00137B7C7F +--PLQRHITGYLAQQPGVYGLYFVDLESGQEF-GYHSQTIFHAASTFKIPMNLYLYRAAE +HGQIELSEQLLFTETHMEGGTGILKSHTPGGYSIAQLADYSILYSDNVATNILLTRL-GK +ENVKEYMRSLGGQVVD--------------NEQNITCPYDLALYMQEVIQ--LAKKPSGE +KLLDNLFDNLL-KDRIPAPLPPGIKVANKIGTWPTNTYNDAAYVVHPDK-PYILVITSEN +TP-GYSAAREVIRHLSELVYHY- +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. KC216 TaxID=2530370 RepID=A0A4R4M2Y8_9ACTN +--DVAARIEAEFRSAGVTGFLHTVDMDTGREV-AVRAGAPVVLASVFKVPLLVTFHRQAA +EGLLEPSEQVTLPAEGRTTPTGVSGMLDEARLSLRDLTFLMITISDNAAADVVLERV-GR +DAVNATAAALGLRDTVVEVSGRELHEALDPARTSRSTPRDMTRLLSMIWRDEAAPPAGCA +AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +PLAVLPQADAVIGTAARIAVEH- +>[subseq from] Beta-lactamase class A-like protein n=2 Tax=Candidatus Woesebacteria TaxID=1752722 RepID=A0A0G0S6M8_9BACT +-eQVQKEFNEKTKDLSGIYGLYVISLSNGFFY-GVNDGEVFQAASLIKLPVMAAMYKEAE +NGNLNLDDKYTLKKSDKVAGSGSLYGKPAGYVTYRNLVELMGKQSDNTAFNIIRKLL-GD +EKINDLIRSTGMVDTSLEE--------------NETTPRDIGIFFEELMKGNIVSTNTRD +KILESLTDTIY-EDWLAAGIPEGTRVAHKYGREIH-VVNDAGIVFSDN--PFVIVIMSKG +VV--EREADSVFPELSKLVFD-- +>[subseq from] Uncharacterized protein n=1 Tax=Selenomonas ruminantium subsp. lactilytica (strain NBRC 103574 / TAM6421) TaxID=927704 RepID=I0GNK2_SELRL +-eDLNANTARIIGDSKNQMSVYFLRPDREIEP-FLYNQRQMSPASIIKLFVMAKTMQDIH +DGKLSLDDRITIRKNDVVGGAGVTTWYDGQQRTIRQLLTVMITDSDNTATNILIDKL-GM +KEINRYIAQSGYSDTMLAHKMMLSN----GGRKNLSSVRDLGHLLTKLYYHQLVGPEEDE +FMLTILKQQHD-KECLGSALT-GYTVAHKTGEVT-GVYADGGIFFGAQED-FILVILNNG +NEG-------------------- +>[subseq from] Serine hydrolase n=3 Tax=Streptomyces TaxID=1883 RepID=A0A3B7RHP9_STRFR +---AQRAIRGMFADAGVRGWLHVAELHREARV-TVDPDEPVPVGSVYKVPLMAAFCRLAD +AGALDPRQPVTLGPDERMPRTGISILRDPITVSLRDLVVLMMSVSDNTSADAVLRHV-GP +AAVEELCRDLGLPDTHILGGAATTFEVYNPLSKASSTPSDMARLLRAIWTDGAASAESCA +FMRETMGQQAW-SHRLASGFPDDVTVSGKTGTFGT-MRHEAGVVELPDGGVYTAVVFTQA +ARADLPRADAVIGTAARAAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus opacus PD630 TaxID=543736 RepID=W8H8W8_RHOOP +-------------------------IDDGGDI-AVGADDLVVLASVYKLPLLVALCRAFE +SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLAMSMMTVSDNAAADLVLGQV-GL +ESVERALSELGMTSTRIIGGTADAHRAYDPSYASATTPRELTSLLDAIWTGRAVPGPQGE +FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA +ARTDLPVVDAAIGHAARIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Mucilaginibacter kameinonensis TaxID=452286 RepID=UPI000EF773A2 +--KLTAKLNDAVKDFHGQVGIYVHNLKTGKTA-EINADTLFPTASMIKVSIQCGVMDKIE +KGELKYNQKLVYRDSLLYAGEDILGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GS +EYINNWLDQNGFKVMRVNSRAPGREAMRKIYGWGVSTPREMCRLFTLIREGKAVSAAASE +RMYRNMGRIYW-DEHALSQIPPYVHAISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH +NKTPNNEAGLLIKKVSALLWHYf +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter senegalensis TaxID=446692 RepID=A0A0U5ES95_9PROT +---LAQSISKTVKAQPGHFAVYAALSGHSPAV-CLNCDDLINAASTIKLFVLDAAYDAFT +KGTLHPQDTVTIHNRSLVGTGTFAYAQAGKPVPVSELLRVMIQYSSNLATNLMVEKL-GV +MPIRSVVKAQGLDGIVFGRMIEDFDAN-DKGIRNQVSARGLGAFLQKLDNGQIVGKAQSQ +SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGKHYILVVLTSD +LP-DEQAGIKVLNTLSHQTYTYf +>[subseq from] Uncharacterized protein n=1 Tax=Ruminococcaceae bacterium CPB6 TaxID=1572656 RepID=A0A1W6WF51_9FIRM +-eTLQKKTAALIEDAAANVSVLVQDIAGRQPLlAFGEQRRLVSASTIKTQILLTVLDEVR +QGKRNLQDMVSIAPADILPDSTAFDRPVA-AASLEELLYWMVCISDNTATNLMIRLV-GM +DAVNRYSSELHLTDTSLQRKMLDHNAV-RQGRNNYTSPRDMLCTYRALAQKTILTPQLCS +YALSLLSRQQD-KTVAFRYIWEPLQAAHKTGELR-GLDHDTGLLFLNGH-TYFFGLFATD +GS-SNRENQQLLGRLFRMLVDY- +>[subseq from] Serine hydrolase n=1 Tax=Arachidicoccus ginsenosidivorans TaxID=496057 RepID=A0A5B8VNN4_9BACT +-kHLQSALTALLRGFHGTAGVYVENLKTGSVA-AVNADTIFPTASIIKVPILIGIFNKIK +TGDLSYNQTLIYDTSRTRGGSGLMQFFKDSSTSLDVLISLMISYSDNVAALWCQQLAGGG +VQINQLLENMGFKDTRVNSRTPGREKAYSNYGWGQTTPREMATILKLIREQKAVDAASSD +CMYRQMSHIFY-DGYALSQIPPYIQTASKQGMVND-SRSELVMVNAPHGD-YVFYIATKN +NKEKDAEPWELARQVSALLWHYf +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A329UKU0_9FIRM +--TLEKRIAAELYSYQGKMSVFVDDL-QGHTV-EIGADEKFETASTIKAFILAALYLQVS +RGKASLEEEITYEESQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFADTVLHNPLH-FD---RYDDLGTTTPRDYAALFAQVAKGTLVSKEASA +EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus horikoshii TaxID=79883 RepID=A0A5D4SZG6_9BACI +--ELKERVQAVVDSTAGHVSFMLED-NCGQLL-EKDCDVPKKAASLIKIPLLMAALKQVE +AGNINLSDRMNIESESRVGGAGVIQYLDQDTFTLCDFLTLMITVSDNSATNKVIDLI-GI +DSVNKFCTEQGLSNTILERKMMDVKAS-DAGLENRTCARDIVACLKILLDSNVLNVESKQ +LMMSMLRGQQL-LDKLPFFMNNTVQVANKTGELP-GVEHDCGIVTFGEK-SLIMAVLVDN +LIE-NPSGKRAIQKIGRIIE--- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2W6AUW2_9CHLR +--NLQKLLEQSVAGLAGDWALAVKKLDTGQMA-MVRGNERFVAASLYKLDVLLAVASLHA +QGKLNYDDTITILDDDIEDYANGDPGDPGTVLTVQRTAELMIDESNNTAAAMLIRTVGGQ +NAVNSTLQDYGLGHTIYDPNN-----------DNLTSSGDMMRYFEMLYSARLVDADESK +WMLDILLRQEL-NFLIPANLPDNVPVAHKTGNLPN-LMHDAGIVYSPGG-PYAIVVLAQN +LD-SEDTARAMTPQISQAVYDYf +>[subseq from] Serine hydrolase n=1 Tax=SAR202 cluster bacterium AC-409-J13_OGT_754m TaxID=2587834 RepID=A0A5N8YIQ0_9CHLR +--NLDRELGFMAKSFPGIAGIAVKPLIGNAFI-SINGDEIFPTASTIKIHVLTQLLRKAE +KGVFNLNDVLDIRKHPLVQGSLITSSLEGPVLSILNLAILMILVSDNLATNICIDLA-GI +AETNTMIRSLGLPKTTLSRKMQDKA-SIRKNNENISTPNECITFLELLKQGQP-SPTVAE +RCISILTKPKTG--PLNRAIP-NVPISNKPGTMGR-VACDVGIVNLDNY-PYYIAIMTKF +GMLEALEQTQFLVDVAKTVHQ-- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522SKK6_9BACT +-kKLTMELQKLVNNFRGTAGVYVYDLKTHREA-AINADTLFPTASIIKVPILVGIFKKIQ +EGELNYHQPLLYHDSLAHGGSGIMQYFKDSTTNVSVAVTLMISHSDNTAAHWCQALAGGG +AAINSWLADRGFQFTRVNSQTPGREKADDMYGWGQTTPREMAHLLCLIRENKIITPAACE +RMYRDMTHIFW-DDYALSQIPPYVQTASKQGMVD-ASRSELVMVNAPHGD-YVFYVATKN +NKKPDNEAWQFARNVSALLWHYf +>[subseq from] Serine hydrolase n=1 Tax=Cytophagales bacterium TaxID=2053541 RepID=A0A521GHJ6_9BACT +-kTLERDLRALLTGFRGDVGVYVRNLRTGATA-TINADTTFPTASTVKIPIQCGLFDKIN +KGEWKYGQEIVYRDSLYYDDGLIGQLKDSAKIPLSEVVMLMETTSDNTASLWCQAMAGGG +ASINAWLDANGFAKTRVNSRTPGRREFQKQHGWGQTTPRELAELLVYIREGKAVSPDASD +RMYRNLCRQYW-DNDGLSQLPPEVKVGTKNGAVNR-SRSEVVLVHAPHGE-YVYCLMTKN +QAERNNEGFELLRRVGALLWKHf +>[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium 46-32 TaxID=1895839 RepID=A0A1M3FXT9_9SPHI +-qQLLHKIRQAVQGFNGDVGVYVKNLRTGRVT-QINADTHFPTASIVKVPIMLGIMDKIQ +RGELHYDSAHVYRDSLLYEGEDILGSFKDGEILLKKIIMLMLTTSDNTASLWLQKLAGTG +TRINEILDSAGLRQTRVNSRTPGREPNRSIYGWGQTTPAEIARLFELIYTNKLYTPAACD +RIMRCLGRNYWDEAEAISQIPPTIEVFSKNGCVN-AARSEVLLVNAPHN-PYIFCIFTKN +NKQRSNEAWTLARKLSALVYQHy +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces asterosporus TaxID=285570 RepID=A0A514JRN2_9ACTN +---------------------------DGREV-AVDADTPVVIASIFKVLLALEFARQAV +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNTAADLLLARV-GL +DTVQLLARELGLERTRIVGGPRDLLEVLDPRHTTASTPRDITRLLRLVWTDRAGPPEACA +LVRDLMHRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGAHYAIAVFART +RDASRPTVDAAIGRAAGMA---- +>[subseq from] serine hydrolase n=1 Tax=Echinicola rosea TaxID=1807691 RepID=UPI0010CA7869 +-kKLTAGLNALMEEFQGTAGVYVEHLPSGKYA-AINADTIFPTASIVKVPILIGIFDKIE +KGELTYHEELVYRDSIKYGGSGLMQFFEDSTTDLSTLLALMITYSDNTTSLWSQALAGGG +ETINPILEKNGMEFTRVNSRTAGRTRDWEKYGWGQTTPREMATLLKKIRKGQVVSKAASE +RMYRLMTNVYY-DDYALSQIPPYIQTASKQGMVN-ASRSELVMVNAPHGD-YVFYIATKK +NQEPDNAAWVLARKVSALLWDYf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNQ865 TaxID=1288081 RepID=UPI0004210501 +hrTARSRIRRAFTEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE +HGRIDLTTVVDIPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI +EAVNRTMAALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA +DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Heliobacterium gestii TaxID=2699 RepID=UPI00136CB032 +---LKQQIQNYLNTRPGQVNLFVQDVTTGAKM-DIGGDEIHRTASTHKVPTVMYLYRLAA +QGKVDLDAKLTYTSQYYRQGTGILQTKPYGGYTLRELGRLSIVYSDNVAWAMLLDYL-GR +DNVNTFMRSLGGNVTGSDAKGYF-----------ITTPRDMGKYLGALLLFRDAQPQLGG +EIFHAMENTIF-NDRIPAKLPTGTVVAHKIGSLDD-SIHDVGIIFANNR-PFILSIYSKN +GWE--AASTDTLAQVSKMIYDY- +>[subseq from] serine hydrolase n=1 Tax=Bacillus jeotgali TaxID=129985 RepID=UPI000C84C34B +---LRERLLKELAGCKGRASLFLEI--EGEII-EVNSQQVYQSASLIKLPILIEALRQIE +EGKLQKDRLVTIRESDKIGDTGVLQAMNVKQLPVEDLLSLMIIVSDNSATNLLIDLI-GI +NSINSTLSRVGMKNSILQRKMLDFD-AIQSGHDNFTSAADIALCLKEAVAGGALNKQSKN +TFFSFLLQQQF-KEKLPFYLDALLKIGNKTGELP-GVEHDCGIITYGKK-QAFIVVLIDG +LSEP-DSGKTIIRQIGKHI---- +>[subseq from] Uncharacterized protein n=1 Tax=Rhodococcus opacus (strain B4) TaxID=632772 RepID=C1AR65_RHOOB +--SAEKRIRDVFADAGCTGWLHARRVGTPAEV-GVGADDLVVLASVYKLPLLVALCRAFE +SGELSPTATVRVNPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL +ESVERALSDLGLTNTRIIGGTADAHHAYDPSYASATTPREMTSLLDAIWAGRAVPGAQGG +FVRQVMSAQIW-QHRIRSGFPSGVDVAGKTGTIG-AIRNEVAVVTFPGEIPVAVAVFTRA +ARTDLPVVDAAIGHAARIAVT-- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. S4.7 TaxID=2705439 RepID=A0A6C0PXW4_9ACTN +----RDRIRAAFADAGVTGWLHAADIDSGAQI-DVGADRSVVTASVHKLCLLVALHQHAE +TGRLDLTDQTECPGDGRTAGPTGLSAMLDPALSLRDAAYLMMAVSDNTAADLLLERV-GL +DAVNGTTQRLGLTRTHAVQTFRDFIAALDPARTNHSTPRDMTRLLGAIWRDEACTPEHGA +AVRRLLALQVW-PHRLASGFPDDVHVAGKTGSAPT-LRNEVGVIEYPDHGRYAVAVFTRA +ASATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Apibacter sp. HY041 TaxID=2500547 RepID=UPI000FE37E51 +--EFNDSIYHLIKNKKLDIGISVRDNTGDEIV-SYNQNKKYKLYSVSKYFLGLYILDQVD +KGNLNLNQPVIFSKKDLKPYSPLRDSIPGTTLTLKESIKYLIEDSDNNVFDKLIDISGGF +QRLNLFVHQIVPNKFAINAGYSDSETL---FQSNVITPSLTTEILYKMENRQIISDESLN +LLKFYMQHSVN-NKRIQGLLQTKTKSFHKSGTSGRKATNDIGIVELQDEQSFSIAVFISN +SHEDDATNEYIIAKLADIIYD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces calvus TaxID=67282 RepID=UPI001153BAF6 +---------------------------DGREV-AVDADTPVVIASIFKVLLALEFARQAV +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNTAADLLLARV-GL +DTVQLLARELGLERTRIVGGPRDLLEVLDPRHTTASTPRDITRLLRLVWTDRAGPPEACA +LVRDLMHRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGAHYAIAVFART +RDASRPTVDAAIGRAAGMA---- +>[subseq from] serine hydrolase n=1 Tax=Rudanella sp. HX-22-17 TaxID=2614655 RepID=UPI0012617294 +---LERDLRAMLSAFRGDVGVYVRNLRTGETV-AINADTLFPTASTIKIPIQCGLFDKIH +RGELKYGAELVYKDSLHYDDGIVGQLKDGARLPLSQVVMLMETTSDNTASLWCQAMAGGG +AAINAWLNANGFTQTRVNSRTPGRAAFQKQYGWGQTTPRELAELLAYIRAGRAVSPDASD +RMYRNLCRQYWDGDGL-SQLPPEVKVASKNGAVNR-SRSEVVLVHAPHGE-YVYCLMTKN +AQDENNEGFALLRAVGARLWKHf +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. MJ1a TaxID=2599294 RepID=A0A563U959_9SPHI +--KLTSQLQGLLKNFNGTAGVYVHNLKTGKTA-AINADTLFPTASMIKVSILNGVMDKIE +KGELKYNQKLVYRDSLLYAGEDILGSFKNGDIQLSKVTMLMITMSDNTASLWLQKLV-GG +EYINNWLAANGFKVMRVNSRTPGREAMRNIYGWGVTTPYEMCKLFTLVRDGKAVSPAASE +RMYRTLNRIYW-DEHALSQIPPYVQAISKQGAVD-ASRSETVLVNAPHGD-YVFSIITKN +NKTPENEAGILIKNVSALLWRYf +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0011D21748 +--SHAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKAIIEASMTDSDNTANNKIIKEIGGI +KKVKQRLKELGDKVTNPVRYEIELN----------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase TEM n=2 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=A0A3P6LA62_LYSSH +--QLKEELHRIANDVAGDVSIYATT--SDGVI-AIREDEVKRSASILKVPVAMACLEAAD +RGEIDLDTVLEIEA--PVGGSGVLAYMSDMEITLRNALTLSIIVSDNTAANLVIEHV-GF +ERIQSFFNQVGTTHSQLTRKFMDYD-ALAQGLENVATARDMVRFLACLDPSEILSLTSKQ +QLKTIMRDQQL-IDKLPAFQPETLIIGNKTGTLP-GVEHDIAYFESGEK-RVDIAVLTTN +WEYN-HDGQQTLAQIGKAIIQY- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535RZX5_9CHLR +-nALRDSLDGAVAEFDGHAAVVVSGVDTNFRY-AKNDDAVFPSASLYKLEVMVEAYRQVT +AGRISLDDTVTVVWDDMSV-DP-SDTLPGTTLSVRDAVERMITLSDNGPAHALMRLL-DP +HNVNATTLSVGLKDTRINAALPPDE---QLSEDNTTSARDMERLFAGLATGKIVSPDASA +EMLATLFRQQI-NDRLPTGLPADAALAHKTGDLI-GVSHDAGLLLTPFG-PRVVVVLTSD +FS-DYDDVARLMARVATAAYT-- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcales bacterium UBA10510 TaxID=2055795 RepID=A0A354AZE8_9CYAN +--DLSKRWAQLAAQSEFQASAFLLVLDDGRYA-ALQADLAMPAASSIKNPILLAALQDLD +ASKLRWNESLPLTAEVQAGGAGWMAKPLGTSFPVYETATEMIRVSDNSATNLLIKRLGGK +ELLNARFQTMGLNATAVNTWLPDLKGT------NTSSSRDLARSIALVDIGQALSPRSRD +LFREIMSQSHT-NTLIPLGLLQGVRVYNKTGDIGI-AYADAALIELPNGHRAVAAFMVKG +PFND-PRSANLIRAMAAAM---- +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis xylanica TaxID=589385 RepID=A0A1H3N104_9PSEU +-------------KAGVRGFLHARHLGSAAEV-SLDADEPVVLASVVKVPLVLEFARQVA +AGQLDPADRVRARAADRLGGTGMAGCADDVEMSLRDAALAALSVSDNTAADLLFDRV-GV +GNVRSLMTELGLTSTRIIGAPKDVLRALDPLRTTASTPREMTRLLELIWRDEAGPPEACR +QVRDLLGFQIN-WYRVAAAFDDEVAYAGKTGTLPQ-IRNEIGVATYPDGEQYAIAVFTTG +RYGRRPDIDQAIGAAARSAVDQ- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A3N5MR70_9BACT +--NLDTRIRAEISRFEGKVSLFAKNLDTGTTY-AFGADDMVRTASTIKIPVLVEAFAQVA +EGRVRWADKVILKDAKKISGSGVLQELSDGLLTLRDAVTLMIVLSDNTATNLALDVL-TT +DAVNARISGLGLKHTFLLRKVGGGGVKAGEDPAGVTTPREMVFLLEKLERGEVISPAASA +EMIKLLKRTQ-GHEGLGRTLQ-GVEMATKPGALDR-LRSEVGIIYTKRG-RIAVAITCDD +MPK-------------------- +>[subseq from] Beta-lactamase class A n=2 Tax=Rhizobiales bacterium GAS113 TaxID=1884352 RepID=A0A1H1H3K2_9RHIZ +---ASDIVAALRDRDGIDVGFSAIHLASGQCL-EINASSLFPTASVFKVPVMVEVFRQAR +AGIFAMSDRLTLATCHKTLTSGVLVTLDDGLPTIGDLVMLMTIVSDNTATKLLLDLV-GM +DKVNAATAGYGLHDIHVAIDVHEMFLTFSRERDNTASAADMARLMAMIAAGEVVDAEACG +SMVAIMKEQQY-SERVPRYLPFG-SVANKTGTMR-GVRNDSGIMRRGEGDDIAYTVFTFD +PTPLAAGNSRFLAE--------- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=A0A0P6VYI1_9BACI +------------------------------SF-HINGDSTYSAASLIKIPILLEGFRQAQ +EGKISLSDRVTIPKEGRVGGAGVLVSLSDHLLTVEDLLTLMIIVSDNTASNLLIERL-GS +IAIQDLCDTLQLKQTMLRRKLMDFEA-VEQGLNNYTSALDIISCLKVLDIGTEYSPTSRK +KMLHILHQQQF-DTKLPSRMDRGVYIANKTGELP-GVEHDSAIIKFREKT-AYIAVLIDE +LGQN-EPGKDTIAQIGKLMS--- +>[subseq from] Uncharacterized protein n=1 Tax=Anaerolineaceae bacterium TaxID=2024896 RepID=A0A2E0ZEE4_9CHLR +---LLEQIREICEAFDGRIGLSATNLQTEETV-GHQAEEVFPTASVIKLPVLLTLMQQVE +DGLYSLDDPLMLRRGDKIGGSGLLQYLSPGLMSLRDWALLMMSISDNLATNVLIDHV-GL +EQVQQWLNDNGYPNVKLRRKIDFNILNKDQNELGTATPAGLTRMIMAVFQQRHLTPAACT +EMLRMMN--KVGYDRVGRYLPKKLQLAGKTGSLK-GMRAQTAVVYPEQNNGFALTIMNEG +NPQPDAPGVLVIGRLTRLIYDAw +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02056 TaxID=1703924 RepID=A0A1Q4VIE1_9ACTN +-------------DAGVTGRLHARDLDTGAEI-GLGADTAVSTASVHKLCLLVTLYREAA +AGRIDLTRQVDVPAAGRTPGSTGLGAMLDDALSLRDLAYLTAAVSDNTAADTLWDRI-GL +DTVNRTMADLGLTRTVAVHKLRDLIAVLDPAFTNHSTPRDMTTLLAALWHGDACPGDHGA +ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA +AATTLPAADAAIGTAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Acetobacter farinalis TaxID=1260984 RepID=UPI00140C2978 +-eALQQSIARTVQAAPGHFAVYAARSGQAPDV-CLNCDDLINAASTIKLFVLDAAYAAFA +KGQLSPEETITVHNHSLV-GSGTFYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV +LPVRSVVKAQGLNGIFFGRMIEDFDAN-DQGIRNRVSARGLGGFLQKLDSGRIVGKAQSQ +SMVQIMLGQTF-NDIIPPGLPAGTPVAHKTGWVD-GVRNDAALVTLPDGTRYILVLLTSD +LP-DEQAGIKVLNGLSHQVYGYy +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. IB2014 016-6 TaxID=2517818 RepID=A0A5C8QCX3_9ACTN +----RDRIRAAFADAGVTGWLHAADIDSGAQI-DVGADRSVVTASVHKLCLLVALHQHAE +TGRLNLTDQTECPGEGRTTGPTGLSAMLDPALSLRDAAYLMMAVSDNTAADLLLERV-GL +DAVNGTTERLGLTRTHAVQTFREFIAALDPARTNHSTPRDMTRLLGAIWRDEACTPEHGA +AVRRLLALQVW-PHRLASGFPDDVHVAGKTGSAPT-LRNEVGVIEYPDHGRYAVAVFTRA +ASATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Actinomadura montaniterrae TaxID=1803903 RepID=UPI00124D540E +---TAVRIEAAFRDAGVTGFLHAADIDTGREV-AAGADAPVVLASVFKVPLLVAFHRRAA +EGLLDPTEQVTLPAGDRTSPTGVSALLDDVRMSLRDLACLMITVSDNAAADALLDRV-GL +DAVNAAAAALGLRETVVTGGGRQLFDALDPSRTSRSTPRDMTRLLAAIWRDEAAPPDGCA +AMRRLFGLQVW-PHRLSSGFPDDVLVSGKTGTLLT-VRNEVGVVEYPDGGRYAVAVFTRS +LLAVLPQADAVIGTAARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNS335 TaxID=1169160 RepID=UPI00035CCC1A +hrTARSRIRRAFTEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE +HGRIDLTTAVDIPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI +EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA +DLRRTLGAQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAARLAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Microgenomates group bacterium ADurb.Bin219 TaxID=1852933 RepID=A0A1V5VRD0_9BACT +----KKEIADLVSPLKGNYGVFVQDLASGKSY-GYNEDQVFDSASLNKLPLLLALYREAE +AGNLDLETKYSLRVGDKRPGAGSLQYPVGYSLTYRQMAELMGKQSDNTAFNVVSRIL-GE +EKVQRLIDDLGLKKTSFVDWE--------------TTPADIGLFFYKLYTQNLLIRDDRD +ELLSFLTETIW-EDRIPTGIPNGIRVAHKVGSEI-GVVSDAGIVFAK--KPFILAILSRG +VL--EKEAKEVLPKIAELVYKQf +>[subseq from] Serine hydrolase n=1 Tax=Kribbella pittospori TaxID=722689 RepID=A0A4V2M886_9ACTN +----SARIRAVFEDAGVRGWLHAVALDSPDSTvEVDADTVVPMASVYKVPLLAGFCRLVD +LGEVDPRQQLTLDPSTRTAPTGVSILADPVTMSLRDLAVSMMTVSDNASADALLDVV-GL +QRLAELLESFGLKRTWVRRGTAGNLRVYEAANGSASSPRDLTTLLRRLWTGELLSEEQTA +FVRATMHRQLF-MHRLASGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGAAFAIAVFTLA +ARGDQPRVDAAIGEAARVAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Microcella alkaliphila TaxID=279828 RepID=A0A4Q7TZ77_9MICO +---LQQTVDALEERWGLTAFVHGMALDGDADV-GVRADEPVVAASVFKLPVLVEACRQIA +AGDIDPTRRFDLAPDDFAVLGPTGIAVFADPLSFRDLCLSMMSVSDNRATDVVMDAV-GL +ERVNATMRALGLGSTVLEGDCAALFAALDPRRTNRTTPREASQLLARLWTDRGIDPSACA +EARRILGLQVW-SNRLRAGFPDSVRVSGKTGTLLT-VRNEVGVVEHPDGGRCAVSVFLRL +PAADVPHFDHAIGEIAAAAVA-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces roseus TaxID=66430 RepID=A0A0J6XFD0_9ACTN +--DTRRRIAAAFTEAGVSGRLHAVDIDSGTEI-DAGADHPVVTASVHKLCLLVALHQQAA +AGLLDLTEQVECPPADRSAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARL-GL +DAVNGATARLGLTRTRAVHSFRSLFAALDPARSNRSTPRDMTRLLTAVWRDEACTPEHGV +AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA +ANATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. CC9616 TaxID=110663 RepID=UPI00048D7073 +--ALSEKWKQLAAQKDLKTSAFMLILDDGRFA-QLEAERPMPAASSIKTPILLASLELID +NGDLHWNEPLILTKELIGGGAGWMAKPVGSRFPTYEVATEMIRVSDNSATNLLIERVGGQ +AAVNARFQALGLPATEVNNWLPDLDGT------NTTSARDLSRSIALVDSGETLSPRSRD +LFREVMSTSVT-DTLLPTGLLQGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVQG +PFN-DPRSTDMIRALAKAMA--- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E8HKH2_9BACT +-----DEIEEIAEGFQGRFGFYLEDLASGATH-ARLEEERFPTASMCKIPVMVELYRQVA +GGGLSLGERRRLVGEISRHGSGTLSLMWDHPLTLADYCRMMMAVSDNMATDFLMSVV-GL +GNIDRTMDELGFSNVRTPMTIGRFHYYSDSIQNNVTSPTEMALLVKRIHLGEIVSADASA +AMIALMKGCRD-RRMMARYVDPEIEVAQKTGSSGR-IKGNTGMVYLPSG-PLLISAYGLA +AA-DDVDGGEAIARISRLAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CNZ279 TaxID=2035251 RepID=A0A2G7E4K4_9ACTN +----ERTLRALFDDAGVRGWLHVAELRRTARV-TVDADETVLMGSVYKVPLTVAYCRQVD +AGVLDPRQRVTLPPQDRLPPTGISHLRDEVTMSLRDLVVMMLSISDNAAADAVLRQV-GS +TAVDDTCRALGLVRTRLNDGAAGTLAVYDPAWATATTPAEMARLLRAVWLDEAASPDSCA +FVRRSMGLQPF-QHRLAAGFPDEVAVYGKTGTFG-AMRHEAGVVELADGRAYTAVVFTQA +ARADLPRADAVIGAAARTAVEH- +>[subseq from] Uncharacterized protein n=1 Tax=Microbacterium sp. Root61 TaxID=1736570 RepID=A0A0T2L253_9MICO +---ALERVRQLSAQTGIGVFAHAIDIDSGRGL-GVQSDSAVVTASVFKVPILLEYARQSD +AGELDAARSLIVDPATVTLGPTGLSVFSDPTWSIRDIATSMITVSDNAATDILLELV-GR +DRVNETMSAFGLPGTFLEGDCQALFEANTPEVTNRTTPRESTRLLQLLWTDAAGTPAACA +EARRILGLQVW-PHRLTSGFPGEVALSGKTGTIGV-VRNEIGVVEYPDGARYAVAVFLRI +PRSRAPEADALIGAVGRTLVD-- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. XXST-01 TaxID=2492960 RepID=A0A431W3F2_9BACI +---LVDSIRKQIELCPGRISLWVEI--GDWSF-EHDSERVYSSASLIKVPILIEVLRQNE +KGLFSLADSLQIGEGQRVGGSGVIQALEQSFWTIKDLMTLMITVSDNTATNMLIELL-GM +DAVNESMELMGLKKTKLQRNMMDFT-ALQQGTDNQTCASDMIRCLKVIDECGFLTEKSCH +EAKKILQHQQF-HKILELLDSDKGYMGSKSGSLP-GVEHDCAIINYEGKT-AYVAILIDQ +IP-DGKSGTLSMKEIGKAVFD-- +>[subseq from] Beta-lactamase class A n=2 Tax=Edaphobacter dinghuensis TaxID=1560005 RepID=A0A495BQI2_9BACT +-eALQREVAAIAGAHQGQVAMYATQLNTGRIV-ALHADEPVQTASVIKLTILFEAMEQVR +AGKAHWDEKLTLAKGDAVSGSGLLTFLDAPVLTLKDVLTLMVIMSDNTATNMAIDRF-GI +DAVNQRIGWMGLKDTHLYKKVMKMPADQPKFGLGKTTPREMAKVMERIGRCQLAGRGEEA +QALQ-MLRNQFYRDTVPRYLEEGSGIASKTGSLNT-VRNDVAIVAGKSG-PMILSIFTYD +DQDQDNQAEVTIAKLAKAIVEVw +>[subseq from] Serine hydrolase n=1 Tax=Ignavibacteria bacterium RIFCSPLOWO2_12_FULL_56_21 TaxID=1798438 RepID=A0A1G0SG34_9BACT +--DLQLQLEDAARSVRGTVGIYVRNLETGETA-AVNADTLFPTASMIKVPILCGVFDKIV +SGDLEYDSAYVYRDSLLYAGVDILGSFRDSAITLSKLVMLMIATSDNTASLWLQSMCGTG +TAINDWLERNGFHATRVNSRTPGREELRKHYGWGMTTPREMAELLAYIRVGKAVRPDAGE +EMYRVLSNIYWSD-GALSQIPPTINAASKQGAVDE-SRSEVVLVNAPHGD-FVFCVITKD +LQKRENEASTLIRKVSSMLWNYf +>[subseq from] serine hydrolase n=1 Tax=Halorussus amylolyticus TaxID=1126242 RepID=UPI00104EFB1D +--DLVAHLDSYAEKLDGRLGVFLRGPDDFDVVyRANADETFTSASVIKIAILYALYEKYD +GNLAELDRPREIAPENRVAGSGLFHLLSDPRPSLDDLARAMISISDNAATNELIDEV-GM +ERVEDAASRIGMDDTRLRRKMMATLGWPEGEPANATTPADCARFFADLVHEATLSSDAYD +RMTVPLAEQKY-TGSFPRYLPFETTVAHKTGSVPS-AALDAGYVSISDSTPLVFAVFADE +LEAG-ADGSDAIAEIGDGVYE-- +>[subseq from] Beta-lactamase n=1 Tax=Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896) TaxID=504472 RepID=D2QMG0_SPILD +---LERKLQTALKGFRGDVGVYVHNLKTGVTV-AIKADTLFPTASTIKIPIQCGLFDKIH +KGELTYGQTLIYKDSLHYDDGIVGSLKDGAKIPLSEVVMLMETVSDNTASLWCQALAGGG +TAINTWLESNGFRKTRVNSRTPGREADRTRYGWGQTTPREMADLMTYIRQGRAVSPDASE +EMYRNLGRQYWD-NDGLSQVPPDVKTACKNGAVNQ-SRSEVVLVHAPHGD-YVYCVMTKN +QQERTNEGFALLRNVGTLLWQHf +>[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. 5K548 TaxID=2530386 RepID=A0A4R5BPN4_9PSEU +---AAQRIREVLADAGAQGWVHAVRLGGGDHElGFGADELVVTASVYKLPLLVALARAFD +AGTLDPREAIRLDPGSCTPPTGVSTFQDPVRMSWRDLAASMIAVSDNAAADVILGAI-GL +DALAAALADLGLERTRVVGGTADAHAAYDPSYASATTPREMTRLMELIWADAVASPQQCA +FVRRLLGQQAW-MHRVRAGFPQGVRVSGKTGTIG-AVRNEVSVVEFDGEAPVAVALFTLA +ARPSLPRVDAAIAECARIAV--- +>[subseq from] Possible beta-lactamase family protein n=2 Tax=Synechococcus sp. (strain WH8102) TaxID=84588 RepID=Q7U8A4_SYNPX +------RWRTIATQKDLQTSAYMLILDDGRFA-QMHADRPMPAASSIKTPILLAALQQVD +AGDLHWNEPLVLTKELVGGGAGWMASRPLGSFPTRVAATEMIRVSDNSATNLLIERVGGQ +QTINQRFDDLGLRATEVNNWLPDLDGT------NTTSAHDLSRSIALVDTGEALSLRSRD +LFREVMGSSVT-NTLLPTGLMQGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG +PFND-PRSTNLIRALAAAMA--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces roseus TaxID=66430 RepID=UPI000D1A60B8 +--DTRRRIAAAFTEAGVSGRLHAVDIDSGTEI-DAGADHPVVTASVHKLCLLVALHQQAA +AGLLDLTEQVECPPADRSAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARL-GL +DAVNGATARLGLTRTRAVHSFRSLFAALDPARSNRSTPRDMTRLLTAVWRDEACTPEHGV +AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA +ANATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus sp. OK270 TaxID=1882814 RepID=A0A285DZ56_9NOCA +--------------------------DDEDAV-SVGADELVVTASVYKLPLLVALCRAFD +VGSLSPTATVRINPADCTPPTGVSTFRDPVVMSWRDLALSMMTVSDNAAADLILGRV-GL +DGIDRVLAELGLLRTRIVGGTADIHRAYDPAFTSATTPREMTSLLDAIWTDGVVSADQGQ +FIREVMAGQIW-PHRIRSGFPAGVTVAGKTGTIG-AIRNEVAVVGFPGETPVAVAIFTRA +ARADLPVVDRAIGRAAHIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Selenomonas sp. FC4001 TaxID=1408313 RepID=UPI0009E079E9 +--------AQVIGANNKQLAVYFLRPGREVEP-FIYNQRRMFPASMIKLFVMAKTMQDVH +DGRLSLEEQLTIRKQDVVGGAGVTTWYNAGERTIAQLIQLMVVESDNTATNMLIDKL-GM +ANINQYLQQYGYKDTLLVHKLMVNKKA---SNKNLSSVRDIGHLLTNLYYHQLVGEKEDA +FMLDILEQQRD-KECFPAVVS-GYDIAHKTGEVN-GVYADGGIFYGPQED-FILVALSNS +NE--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces nanshensis TaxID=518642 RepID=A0A1E7LYS5_9ACTN +----ERTIRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD +AGRLDPHHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GT +DAVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDEAASPESCA +FMRAAMGSQPW-THRLASGFPDDVAVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] Uncharacterized protein n=3 Tax=Candidatus Gottesmanbacteria TaxID=1752720 RepID=A0A1F5ZWX2_9BACT +--ELKNKIEKELEKTTGTYSIYFYDLTTGDNF-GINEEMIMMAASINKIPILAAVYYSAG +KGIIDLDKIIVPQVTDIQDTGTIRYNKPGTAYSIKTLARLMMEKSDNTAAYLLASVIVGL +DEVQKMVEGWGMTQTDMK--------------SNKTSVKDIFNISKKMYQGEITTPEYTR +EMIDFMDDSDF-EDRIPKGVPLSITVYHKTGDEVR-TVHDAGIIVLPDR-PYYLGVMTTD +IEN-EEETKNKIARISQIVF--- +>[subseq from] Serine hydrolase n=1 Tax=Methanomassiliicoccus sp. TaxID=2528041 RepID=A0A524IY86_9EURY +--RLKSELLKMAKDVKGHLGLFIKHVESGREI-TVDADKTFPLASVFKLGVMVETFRQIE +EGSISLEERIELEPRHYCIGEGVMQYLSPGLPTVGDLLSLMIIATDNTASEMLWKRI-GI +QRVNMLMRELGLAKTSIY------------------------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces albidochromogenes TaxID=329524 RepID=UPI00110F70E8 +---VHTVLASTFTQAGVEGYVHARDLDTGEEL-GHGADSQVVLASVFKIPIALEYARQAA +AGELDPARRHTVTAAYRAGGSATDGCAYDVEMSARDLAFMMMTISDNAATDLLLDVV-GP +DRVRATLDGLGFPGFGFSSSAA-LDDACAPGSSPSSTPREVTALLAAIWRDEAGPASACA +EVRDIMGQQVW-QHRLVSGFPAGVRLAGKTGTDF-AVRNEAGVIEYPDGKRYAVGVFLRT +STTRQPLADRAIGRAARLAVDH- +>[subseq from] Uncharacterized protein n=1 Tax=Flavobacterium kingsejongi TaxID=1678728 RepID=A0A2S1LJG3_9FLAO +------------------------------------------------------------ +---------------------------------LDQFLKYTVSDSDNNGCDILLNLIGGT +ETVQKFINKQGINDFTIKVNEQEMKT-WEDLYKNATTPLATTELLEKFYKGKVLKKKTTA +YLYQKMEETTRGTNWMKAGLPAGTELAHRTGFSATDAMNDVGIVKLPNGKHFIISIYIKN +TTEPREDFEKIMAEITKLTWDYy +>[subseq from] serine hydrolase n=1 Tax=Virgibacillus dakarensis TaxID=1917889 RepID=UPI000B42F526 +----------------------LIKTKSGDIA--INACESIRAASMIKIPILIEAYRQIE +RNLLDPETSVDIESEKKAGGAGVINYLTNVNYSYQNLLELMIIVSDNTAANLLLEKI-GV +QHVNKFAAEIGLYHTKIGRKFMDQK-AIEKGRDNYTCAYDMVQLLSLIAENKIVNDDSRK +QMLRILYYQQF-KQKLPAYLHDGIDFFHKTGELP-GIEHDAAIISNKGD-TIYAAILTQN +WV-NNGIGRDYIADIGRLLINY- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadaceae bacterium TaxID=2026741 RepID=A0A2E0DR42_9BACT +-dSLQSRVAARLDRLDAISSIYAKHIPTGREI-AVRADHPMNTLSVIKIPVMVKAFQDNA +SGRLDFGERYTVXPNDMRRGSGLIQTFEPGLPTLRSLVTQMIITSDNTATDMVIKAV-GL +DRVXALLQNEGFSQTRXKATTGDLFRAFEGDSTGKTTAREMGNLLEQILNAELADEEASA +EMIAMLTRQFY-TSRLPQRVRQGVSVAHKTGDWPPIAGNDVGILFYDGG-PSIVSVFTNQ +NTGDFFELEATLGLIAEDIVEAw +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis eurytherma TaxID=196083 RepID=A0A3N2H2E7_9PSEU +------------EAAGVRGWLHARCLDCGGET-GHHPDEPVVLASVVKVPLVLELARQVA +AGQLDPADRLRVTAADRLGGTGTAGCADDVEMSLRDAAFFALSVSDNTAADLLFDRV-GL +DNVRSLLRELGLADTRVIGSPRDVVAALDPLRTSASTPRDMTTLLAAIAGDTAGPPEACH +WVRQLMGQQVN-WHRLTAAFPPQVRVWGKTGSLL-AVRNEIGVAEYPGGERYAVAVFTKA +PTSRLPDVDHAIGEAAKAAIE-- +>[subseq from] Serine hydrolase n=1 Tax=Komagataeibacter pomaceti TaxID=2021998 RepID=A0A318Q7M3_9PROT +--TLSDDIAKTIQGQPGHFAVYAAMSGQPPQV-CLNCDDFIDAASTMKLFVMDAAYDSFT +KGTLHPQDMIVVHNRSLVGGSFALYAAIGRPVAVSELLRVMIQYSSNLATNLMIERI-GV +PYVRAIVAVQHLDGIRFGRMIEDYDAN-SQGIHNQVSARGLGLFLQKLDHGDIVGPAQSQ +AMIDIMKGQKF-NDMIPPGLPPGTPVAHKTGWVD-GVRNDAGIVFLPDGRHYILVMLTKS +LL-DEAAGIRVLNTISRQVHDSf +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura chibensis TaxID=392828 RepID=A0A5D0P0J9_9ACTN +-----SEIAEVFGSAGARGFLHAREVGDGPEV-SVGAEDPVVLASVFKVPVAVAYACEVA +AGRLDENERITVTSGYRIGGIGTAGCADDVTMTWRDLVLFMMTLSDNAATDVVFRRI-GK +AAVDQVLRNLGLHRTRLIGCCADLFAVLDPARTTASTPREITTLLDAVWTDGAGPPAACE +RVRDIMARQVW-PHRLSSGFEPDVGVAAKTGTLP-AIRNEAGVVSYPDGRRYAVAVFTRA +DSDRLPRVDAAIGRAARLAVDE- +>[subseq from] Beta-lactamase class A n=1 Tax=Niastella sp. CF465 TaxID=2135684 RepID=A0A4R2WDZ0_9BACT +-nRLQQKIETQIKDLRGYIGVYVKNLRTGKVA-MVNADSIFPTASMVKVTILIGIQDKIE +KGQLEYHQQLEYKDSLLYAGEDILGSFKSGEIGLHKVLMLMLTTSDNTASLWLQSLAGAG +TRINEILDSLGLVNTRVNSRTPGREANRQQYGWAQTTPREMGTLMEKIYRGEVISKKASE +KMVRLLGRNYN-DEQAIAEIPPYIFVASKNGCVN-ASRSEILLVMAPNG-PYIFSVQTKN +LQDNSNEAWVLTRKLSALCWNYf +>[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Candidatus Levybacteria bacterium GW2011_GWA2_40_8 TaxID=1618459 RepID=A0A0G0WLB8_9BACT +---LRKQVSDYTEKQKGSYSIYYKSLGKNSSF-GISENQIETGASVNKLPIVAALYRLDK +EGKLKLDEKITIQEKDVQDTGSIRYQKMPQVYSMRNLAKLSLRESDNTAAHVLSVRI-GV +DKIQELVDSWGMSQTNMGN--------------NKTTVYDMELLFEKIYKEEVATSANTK +ELLEFLTEGET-EDRLPKNLPKGTKVYHKTGDEE-GFVHDVGIIEVKKGA-YYLGVMTSD +IGDGEDATKKAIAEISKMIYE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID7804 TaxID=2690327 RepID=UPI0013714F2E +---------------------------DGREV-AVDADTPVVIASIFKVLLALEFARQAV +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNTAADLLLARV-GL +DTVQLLARELGLERTRIVGGPRDLLEVLDPRHTTASTPRDITRLLRLVWTDRAGPPQACA +LVRDLMHRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGAHYAIAVFART +RDASRPTVDAAIGRAAGMA---- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A350BNK8_9BACT +--DLQLQLEDAARSVRGTVGIYVRNLETGETA-AVNADTLFPTASMIKVPILCGVFDKIV +SGDLEYDSAYVYRDSLLYAGVDILGSFRDSAITLSKLVMLMIATSDNTASLWLQSMCGTG +TAINDWLERNGFHATRVNSRTPGREELRKHYGWGMTTPREMAELLAYIRVGKAVRPDAGE +EMYRVLSNIYWSD-GALSQIPPTINAASKQGAVDE-SRSEVVLVNAPHGD-FVFCVITKD +LQKRENEASTLIRKVSSMLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. Root431 TaxID=1736535 RepID=A0A0T1Q5S0_9ACTN +haATRRRITAAFADAGVTGQLHAADIDTGTAL-GVGSDTLVPTASVHKLCLVATLYRQAS +LGLVDPTRPVDIPAEGRAPGATGLSVMRDAALSLRDLASLAVAVSDNTAADLLWDAL-GL +DTVNATMIGLGLTRTHAVQTMRELFAALDPTRTNRSTPREITALLAAVWRDEVCPGEYGE +ELRALLGRQAW-SHRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA +ASTDLPAADAAIGAAARIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter tropicalis TaxID=104102 RepID=A0A149U7R0_9PROT +---LAQSISKTVKAQPGHFAVYAALSGHSSAV-CLNCDDLINAASTIKLFVLDAAYDAFT +NGTLHPQDTVTVHNRSLVGTGTFAYAQAGKPVPVSELLRVMIQYSSNLATNLMVEKL-GV +MPIRSVVKAQGLDGIVFGRMIEDFDAN-DKGIRNQVSARGLGAFLQKLDNGQIVGKAQSQ +SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGRHYILVVLTSG +LP-DEQAGIKVLNTLSSQTYAYf +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Firmicutes bacterium ADurb.Bin419 TaxID=1852892 RepID=A0A1V5MHM3_9FIRM +--DLLSIINNIVKNKSDIIRISVYDFETDKSV-NYNDQEHFYAASLTKVVNLLCFLEEVK +NGKFDLNSTYTLKKSDKYVGAKVTYQANGTKYTYRDILSRMISLSDNVGANIIFDAL-GS +NKIDSFCQKYELKDTKIYKKFYDANSAVP---SNYTTAADLTRMLVLLENRVVADDSLAT +MGIEFMKNTDN-KDRIPRNAPKDVVIANKIGSLSR-LAGDMALIYFPDRDPIALTIVVEG +KNINEAEANELIGQLSKEIINYy +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. WB02_MRS01 TaxID=2605777 RepID=UPI0012B351D4 +--TLEKRIEAEIKSYDGKMGIYLDDF-HGNVI-AIHADEAFETASSIKTYILACLFDEVE +KGNKSLEDIIEYKVEHAVDGSGVLAAEPGAKLRVKDAATFMIIVSDNIATNMMIDYL-GL +EKINQCIKALGCRDTVLHNPIHF-E---QYDRLGTSTPRDYASIFIRLAKGELISPRADE +MMLEILKKQHY-NSMITKDFPPFISVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE +FSDAAHPATVFGARVSRMILDQf +>[subseq from] serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=UPI000D92CFB5 +------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE +EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM +DKINETIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ +MLIDILTRQQI-KNKLALYIQDNFDISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG +IPNS-VYGTVTLAKSGKMTWD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1H3X4X2_SELRU +---------QVIGANNKQLAVYFLRPGREVEP-FIYNQRRMFPASMIKLFVMAKTMQDVH +DGRLSLEEQLTIRKQDVVGGAGVTTWYNAGERTIAQLIQLMVVESDNTATNMLIDKL-GM +ANINQYLQQYGYKDTLLVHKLMVNKKA---SNKNLSSVRDIGHLLTNLYYHQLVGEREDA +FMLDILKQQRD-KECFPAVVS-GYDIAHKTGEVN-GVYADGGIFYGPQED-FILVALSNS +NE--------------------- +>[subseq from] serine hydrolase n=1 Tax=Olivibacter sp. XZL3 TaxID=1735116 RepID=UPI0010657DD9 +--KLQKELALLTKDFEGTVGIYVYHLGKRKEA-SINADTLFPTASIVKVPILVGLFDKIE +KKELFYHQPLTYRDSLKYGGSGLMQFFKDSTTDLSVLAALMISYSDNTTSLWNQALAGGG +SAINKVMERYGLQFTRVNSRTAGRENDWKKYGWGQTTPREMAQLLVKIRQGEAVNRAASE +RMYRLMTNIYY-DEYALSQIPPYVQCASKQGMVND-SRSELVMVNAPHGD-YVFYVATKN +LKEEDNSAWQLARKISAHLWRYf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CB01635 TaxID=2020326 RepID=A0A2M9JH43_9ACTN +--AIADEIAAVFAEAGAQGFLHAREIGDGPEV-AVGADAPVVLASVFKIPVAVAYVREVA +AGRLDETERTRVTARYRVGGIGTAGCVDDVEMSWRDLALFMLTMSDNAATDVVFHRV-GQ +DAVDRVLTDLGLSRTRIRGCCEDHFAVLDPARTTSSTPREITRLLDAIWTDRAADPGACE +KVRAIMGRQIW-PHRISSGLDTGVQVAAKTGTLP-AIRNEAGVLTYPDGRQYAVAVFTRA +DSDRRPAVDTSIGRAARLAVDH- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus fabifermentans T30PCM01 TaxID=1400520 RepID=W6T7F2_9LACO +---VQKVVTTNLAGLSGKSSVAVLSVDSSAKV--VENNTKQRAASLIELFIMITAYQQVK +AGTLNLGDTYLLQASDKVGGTGNMQSLPNGTFSYQQVLNRMITDSDNTAANIMINKVGGI +AVVNAEIKRLGLTHTVLARKLMDTS-ALQAGKDNYTSAGDVAKVLKKMYNHQLIDATEDA +AMLDILAKNTD-HTMLPHSLPSEAQVYNLTGAYTYGVKNDAAIIKNNYGA-FVVVMLGEN +GQ--ASAQTKAMNQLGNSLY--- +>[subseq from] Beta-lactamase class A n=1 Tax=Terrisporobacter glycolicus TaxID=36841 RepID=A0A1I3M384_9FIRM +------------KSIEGDVSFYYKNLITNKTV-AYNEEKIMLAASVIKITVLVEAFKQIK +EGKIKKEELFTTCEDDKVPSCGALNYMREGLVTLEDLYILMIILSDNYATNMLIDKL-GM +DNINNTIKEIGLKNTVLNRKMFDSKKATLG-LENYISASDVGYLLEKMYNKDLIDKKSSE +EMISILKNQRLNGKMFLQNLKPKIEIAHKTGEDTN-ITHDVGIVFAK--EPFIVCFCGNN +V--NVPEYERLIQDITYDLY--- +>[subseq from] Serine hydrolase n=1 Tax=Spirosoma sp. KCTC 42546 TaxID=2520506 RepID=A0A514ZVA3_9BACT +---LERKLRAAMANFQGDAGIYVRNLRTGKTV-AINADTLFPTASMVKIPIQCGLFDKIY +KGELTYDQELIYKDSLHYDDGIIGSLKDGAKITLSKVVMLMETVSDNTGSLWCQALAGGG +TSINTWLETNGFHQTRVNSRTPGREANRTQYGWGQTSPREMAELLTYIRQGKAISPDASE +EMYRNLGRQHWDNDGL-SQVPPDVKIASKNGAVNQ-ARSEVVFVHAPHGE-YVYCVMTKN +QKDETNEGYTLLRAVAATLWHHf +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. NCIMB 12038 TaxID=933800 RepID=A0A1Y5LP69_9NOCA +--------------------------DDATDI-AVGADDLVVLASVYKLPLLVALCRAFE +SGELSPTATVRVNPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL +ESVERALSELGLTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWAGRAVPGAQGE +FVRHVMSAQIW-QHRIRSGFPSGVDVAGKTGTIG-AIRNEVAVVTFPGEIPVAVAVFTRA +ARTDLPVVDAAIGHAARIAVT-- +>[subseq from] Uncharacterized protein n=1 Tax=Segetibacter aerophilus TaxID=670293 RepID=A0A512BJI4_9BACT +-kKLAVKLQELVGSFNGRAGIYVQNLKTGKTV-AINADTLFPTASMIKVSIQCGLMDKIE +KGELQYNQKLVYKDSLLYPGEDILGSFKDGDIQLSKVALLMITMSDNTASLWLQKLV-GG +EYINNWLQQNGFVNTRVNSRVAGREAMRKTFGWGVTTPREMCQLFTMIEEGKAVSKAASE +RMSRNLARIYW-DESALSQIPPHIRSTSKQGAVDD-SRSETVFVNAPHGN-YVFSIITKN +LKKPGNEAWTLIRKVSALLWNYy +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A3N5XTA2_9BACT +--ALDARVRAEIAQFPGKVSLFAKNLDSGVNY-GFGADDLVRTASTIKVPVMIEAFAKVA +AGRVQWTDKVLLTDAKKISGSGVLQELSDGLLGLRDAVTLMIVLSDNTATNLVLDVL-TT +DAVNARMEGLGLTQTRILRKVGGGGVANARFGLGVATPREMVLLLEKLERGDVVSREAST +EMIKLLKRQQD-HEGIGRTLK-GVEMATKPGALDR-LRSDVGILYTRRG-RIAMAITCDE +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNH099 TaxID=1137269 RepID=UPI0004BBC9F4 +--TPRSRIRQAFADAGVTGRLHARDIDTGADL-AVAADTPVSTASVHKVCLLATLYREAE +HGRVDLAAPVDIPAAGRTPGPTGLGAMCDAALSLRDLAVLAVSVSDNTAADVLWDTV-GI +DAVNRTMAGLGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA +DLRRTLGTQTW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAARLAVD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Thermoanaerobacter sp. TaxID=1755 RepID=A0A3B8MZC9_THESB +-qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT +DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRIV-GR +DNYIKFMEKLGAYVIPYS--------------NNVTSPRDMSMYMKNLLDYVNAHPDTAG +ELMYYLKNTIY-NDRISYPIPDGIEVAHKIGNLSN-VVNDAAIVFHPTR-PYILTVLANN +VDSDDSYAYTVIRQISKMVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 61 TaxID=2035242 RepID=A0A2G7CVQ4_9ACTN +---TLRRIAAAFAEAGVSGRLHAVDIDSAAEI-DAGADHPVVTASVHKLCLLVALHQQAA +AGLLDLTEQVECPPGERTPGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL +DAVNEATARLGLTRTRAVHTFRSLFAALDPARGNRSTPRDMTRLLTAVWRDEAACTPEHG +AAIRRLLGLQVWPHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA +ASATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 2132.2 TaxID=2485161 RepID=A0A3N1VG01_9ACTN +---TLRRIAAAFAEAGVSGRLHAVDIDSAAEI-DAGADHPVVTASVHKLCLLVALHQQAA +AGLLDLTEQVECPPGERTPGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL +DAVNEATARLGLTRTRAVHTFRSLFAALDPARGNRSTPRDMTRLLTAVWRDEAACTPEHG +AAIRRLLGLQVWPHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA +ASATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus koreensis TaxID=2054903 RepID=A0A2K3UZ37_9DEIO +-----------ARGFRGEVGLCVSDLEGQELL-ALQPVRVFPAASTIKMPLLVLALELAQ +RGELELSARVEMRAADRVSGAGVLHELQGGLLTWQDVLTLMIIVSDNTATNMLIERL-GM +EAVNGWLSERGWAATRLIGRLEQRNEAQRRGERNRTTAREQVELLGALARGELLDGVHTG +LALDILGRQQY-RDIIGRRVPRAYRLCSKSGELS-GVHHDVGLLFTP--RPLIVALLSEG +GTDM------------------- +>[subseq from] Uncharacterized protein n=2 Tax=Bacillus TaxID=1386 RepID=V6T4J2_9BACI +--ELRDRLSNELAGCKGRASLFLEI--EGEII-EVNSQQVYQSASLIKLPILIEALRQIE +AGKLQKDRLVTIKESDKIGDTGVLQAMKVKQLPVEDLLSLMIIVSDNSATNLLIDLI-GI +NSVNSTISRIGMKNSILQRKMLDFA-AIQSGHDNFTSAADIALCLKEAVAGGALNTHSKN +TFFSFLLQQQF-KEKLPFYMDALLKIVNKTGELP-GVEHDCGIITYGKK-QAFIVVLIDG +LSET-ESGKTTIRQIGKHI---- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora orduensis TaxID=1420891 RepID=A0A5C4QFH5_9ACTN +---VGERIEAIFADAGVTASLHAVDLDAVDREaGVRADEQVVIASIFKILLVLEFARQVE +AGQLDPTERVLVTAADRLGGWGLAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLATELGLTRTRVLGGPRELVEVFDPEHTTSSTPREITRLLTLIWRDEAGPAAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA +DQPRRIDVDLAMGQAARTAV--- +>[subseq from] serine hydrolase n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=UPI00130EC27F +--TLEKRIEAEIMSYDGKMGIYLDDF-HGNVI-SIGADETFETASAIKTYILACLFDEVE +KGNKSLEDMIQYREEHVVNGSGVLEALEPGALRVKDAAALMIIVSDNIATNMIIDYL-GL +DTINRCIKALGCKDTVLYNPLHF----EKYDRLGTSTPRDYASIFTRLAKGELISRPADG +KMLEIFKKQHY-NSMITKDFPAVITVASKSGSMD-ACRNDGGLVFTPYG-PYVIVMFHKE +FSDAAHPATVFGARISRMILDQf +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis australiensis TaxID=546364 RepID=A0A1K1S5J9_9PSEU +--SAEAAIDAVFTGAGARGFVHAREIGGTAEV-GVGADDPVVLASVFKIPVAVAYAREVV +AGRLDETARTRVGKRYRTGGIGTAGCADDVEMSWRDLALFMLTMSDNAATDVVYHRV-GQ +AAVDRVLTGLGLRRTRLIGCCEDLFAVLDPARTTASTPREITTLLEAIWTDRAGDPAACE +RVRSMMARQIW-PHRMSSGFASDVAVAAKTGTLPS-VRNEAGVVTFPDGRRFAVAVFTRA +HSERQPAVDAAIGEAARLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. UW179A TaxID=2575510 RepID=UPI000E0EF954 +-----ARWQTLAAEQDLKVSAFMLVLDDGRYA-QLEPDTALPAASSIKTPILLVTLEELD +AGRLSWNEPLKLSKTVVGGGAGWMATPLGTRFPTHEVATEMIRVSDNTATNLLIERLGGQ +ETLNARFNALGLSATKVNDWLPDLKGT------NSTSARDLARSIALVDTGEALSIRSRD +LFREVMGTSIT-NTLLPRGLLRGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG +PFND-PRSTELIRKLAAAM---- +>[subseq from] Serine hydrolase n=3 Tax=Faecalibacterium TaxID=216851 RepID=A0A2J4JP78_9FIRM +--TLEKRIAAELYCYQGKMSVFVDDL-QGHTV-EVGADEEFETASTIKAFILAALYLQAQ +RGKADLAEEITYEQSQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFAHTVLHNPLHF-DR---YRRLGTTTPRDYAALFARIAKGELVSREASA +EMLAILRQQHY-NTMLTHDFPQYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. 16K404 TaxID=2530385 RepID=A0A4R4UFZ5_9PSEU +---AEQRIRDVLADAGAEGWVHAVRLGGGHEL-GFGADELVVTASVYKLPLLVALARAFD +AGTLDPREAIRLDPGSCTPPTGVSTFQDPVRMSWRDLAASMIAVSDNAAADVILGAV-GL +DALAATLADLGLQRTRVVGGTADAHAAYDPSYASATTPREMTGLMELIWADAVASPQQCA +FVRRLLGQQAW-MHRVRAGFPQGVRVSGKTGTIG-AVRNEVSVVEFDGEAPVAVAIFTLA +ARADLPRVDAAIAECARIAV--- +>[subseq from] serine hydrolase n=1 Tax=Mucilaginibacter endophyticus TaxID=2675003 RepID=UPI000E0DB94B +--KLTAKLNDAVKDFHGQVGIYVHNLKTGKTA-EINADTLFPTASMIKVSIQCGVMDKIE +KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GS +EYINNWLDQNGFKVMRVNSRAPGREAMRKIYGWGVSTPREMCRLFTLIREGKAVSPAASE +RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETILVNAPHGD-YVFSIITNH +NKTPNNEAGLLIKKISALLWHYf +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. MYSH2 TaxID=2303333 RepID=A0A372NYP1_9SPHI +--RLTAQLQSLIKNFHGQAGVYVHNLKTGKTA-AINADTLFPTASMIKVSILNGVMDKIE +KGELQYNQKLVYRDSLLYAGEDILGSFKNGDIQLSKVTMLMITMSDNTASLWLQKLV-GG +DYINNWLAANGFKVMRVNSRVAGREAMRNIYGWGVTTPFEMCRLFTLIHDGKAVSPGASE +RMARTLNRIYW-DEKALSQIPPYVQTMSKQGAVD-ASRSETVLVNAPHGD-YVFSVITKN +NQDQDNEAGILIKKVSALLWHYf +>[subseq from] Serine hydrolase n=1 Tax=Algoriphagus aquimarinus TaxID=237018 RepID=A0A5C7AX46_9BACT +-kKLESSISVLTESFHGDVGIYIQNLQSGATV-EINADTIYPTASIVKIPILLGIFDKIE +KEELHYREPLIYRDSIRYGGSGIMQFFKDSTTDLSTLIALMLSYSDNTTSLWNQSLAGGG +AEINELMDRIGYQNTRVNSRTVGRESIWEKYGWGQTTPREIADIFIKLNNRELISTAASE +QMYRLLSNTFY-TDYALSGIPAGVNVASKQGMVN-ASRSEVFLVNSPQGD-YVCAIFTDN +NEDKDNEAWVMTRKISNLIWNHf +>[subseq from] serine hydrolase n=1 Tax=Selenomonas sp. ND2010 TaxID=1410618 RepID=UPI0009079419 +-eSLAQAVEALSNSDSTQYALFVAYPGENRAV-YSYHSTQMRSASMIKVFILGTAMEKIR +DGKLSLYQNLILHSYDKVGGAGVLAGYASGTFTLDTIMRLMITESDNTATNMMIDLL-GM +DEINAYIKRQGYKDTILQRKMMDSQA-VAAGRENYTSVNDLGDFFVKLYHRNCVSPELDD +VMLGYLEGQTD-TECFPAALP-GVMICHKTGELY-GLYDDGGIVYQPGR-HFIIVGMTEN +YS-SRGRAIAILRQMAIAAA--- +>[subseq from] Serine hydrolase n=1 Tax=Sulfobacillus sp. hq2 TaxID=2039167 RepID=A0A2S3QHG9_9FIRM +--NIHQAIAQWSQHFSGRFTLYAEHLQTHEVV-AHEPTRLMETASVIKLPIMIAAMDQVE +AGHLDLATPLVYTRDDYVEGSGVVQNLTPGFLSLHDALTLMITVSDNVATNMVLRQI-GL +ETVNAVMHRLGTPHIHLYKRIDFAQ----PGPIGIAPADEIGGLLKSLYHRTLISPWASG +IMWDILTRQQY-NTIMTRDLPYHVQIGSKSGSLE-GIRNDVGIVTSKWGD-YTVALFSAE +CEHVDNEAMRLLPRLTRLLFDHf +>[subseq from] Serine hydrolase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A233RME1_9ACTN +-----RTIRSLFDDAGVRGWLHVAELDRPSAHvVLDPDEQVPMGSVYKVPLMTTFCRLAE +AGRIDPSHRLTLETADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRAV-GP +EAVDRVCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPADIARLLRAIWTDEAASPGSCS +FMRAAMGTQAW-AHRLASGFPDDVTVYGKTGTFGS-MRHEAGVVELADGSVYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CB02460 TaxID=1703941 RepID=UPI0009A1177F +--QIHTALSSTFTQAKVEGTVHVRDLDTGAEF-AHAADTPVVLASVFKIPIALEYARQAA +SGELDPARRHSVTSAYRAGGSGTDGCAHDVEMSARDLAFMMMTISDNAATDLLLDIV-GP +DRVRATLDGLGLPGFGFSSCS-ALDDACTPGTSPSSTPREVTALLAAIWHDEAGPARACA +EVREIMRAQVW-QHRLVSGFPPGVRLAGKTGTDFS-VRNEAGVIEYPDGKRYAVGVFLRT +STTRQPLADRAIGRAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A1R1K0C0_ALCXX +-qHVDAALAPLLAATPARVSLSLRDLDGGIVL-AHHADRVQPSASIIKVPILLALLEAVA +NGRHALEQPLALPPGDRAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNTLIDLL-GF +DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FT--------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Ruminococcaceae bacterium D5 TaxID=1520815 RepID=A0A1I3PY27_9FIRM +-----NEIYRILSEMKGTVGLYIEDCATGEIL-KINPELSFPACSVIKIPMLALLLRDGA +EGRIDLDAPHKIAAENRVGGTGILCDLNPSYITLRDLGKLMIIMSDNIATNEVMDVI-TV +DRFHAFCKEQGYENIIWQRKMMDFE-AIKQGRNNYLCAGEIGDMLSRISRGEFVSPEISR +TIFEFMCAQKY-RNKLPSLVPAVVLVANKTGDLV-GIQHDVGIFELPSHSRYIISMCTKD +LEND-LDGITTVGKVSLAVYE-- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter tropicalis TaxID=104102 RepID=A0A252A3K3_9PROT +---LAQSISKTVKAQPGHFAVYAALSGHSPAV-CLNCDDLIKAASTIKLFVLDAAYDAFT +KGTLHPQDTVTVHNRSLVGTGTFAYAQAGKLVPVSELLRVMIQYSSNLATNLMVEKL-GV +MPIRSVVKAQGLDGIVFGRMIEDFDAN-DKGIRNQVSARGLGAFLQKLDNGQIVGKAQSQ +SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGKHYILVVLTSD +LP-DEQAGIKVLNTLSHQTYTYf +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. MB95 TaxID=671602 RepID=UPI0013F5B2E6 +----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIMASDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE +KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLITDIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. AF10-46 TaxID=2302955 RepID=A0A3A6JF79_9FIRM +--TLEKRIAAELYCYQGKMSVFVDDL-QGHTV-EVGADEEFETASTIKAFILAALYLQAQ +RGKADLAEEITYEQSQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFAHTVLHNPLHF-DR---YRRLGTTTPRDYAALFARIAKGELVSREASA +EMLSILRQQHY-NTMLTHDFPQYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] serine hydrolase n=1 Tax=unclassified Faecalibacterium TaxID=2646395 RepID=UPI0012AF4AF6 +--TLEKRIAAELYCYQGKMSVFVDDL-QGHTV-EVGADEEFETASTIKAFILAALYLQAQ +RGKADLAEEITYEQSQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFAHTVLHNPLHF-DR---YRRLGTTTPRDYAALFARIAKGELVSREASA +EMLSILRQQHY-NTMLTHDFPQYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A4P5U0C3_9BACT +---LQKQLEKEVAGFKGDVGIYVYELKKDKVV-DIHADTVFPTASIVKIPILLGVMDKIK +KGELAYHQKLIYKDSLLYEGEDILGSFKNGEIELSKVMMLMLTTSDNTASLWLQSLAGTG +LSINALMAQLGFIHTRVNSRTPGRENNRDKYGWGQSTPKELVQLFQQMLKGKLLGKSSDD +LMIKRLGRNYW-DEEALAEIPAGIFTASKNGAVN-ASRSEVVYVNHPKN-PYIFCIMTAN +NSEADNEAWVLTRKISKLLWQYf +>[subseq from] Beta-lactamase class A n=1 Tax=Lapillicoccus jejuensis TaxID=402171 RepID=A0A542E416_9MICO +-----QRLRDLVAAAPGEVALAVRR-HDGAAL-DVGADRVVPSASTIKVPVLVAVLRAVQ +DGRLALDEPVPLPPPERVGGSGPLELLPSLTLPVHELLLLMICLSDNDATNVLLDRVVGP +GAVAAALALVPTRATHLRRRLMDAQAA-ARGLQNETTAADLVDLLVALRERRLLDHERTG +VALDVLGRQQF-REGLPAYLPESVPVASKTGEIF-GVRADVALVEPQPGRWAVVAVVATG +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Ruminococcaceae bacterium TF06-43 TaxID=2292270 RepID=A0A417NH15_9FIRM +--ALKEKILSQLSQMEGQVGFYYKNLVTGETL-AYHENEQFMAASVVKLPLLAAIMLWRE +QGKTCFDEHITVHKEQMHPSSGVLAFMTGDELDIKTLCNFMIIISDTTATNALYHHY-GN +ELVIATLRELGLSGTQFNREYYDSERE-DQGIQNYFVPAEIGTLLEKIYNRTLVSVQASE +EMEKLLLCQQV-NHKMGGSLPVGYPIAHKTGEEED-KTHDVGIVFA--REPFVACFASCQ +SN--IPEFENFIRQTTRSLVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RBG_13_45_10 TaxID=1798370 RepID=A0A1F5ZGB5_9BACT +--ELRRKVEETIKDTWKNYSVLVVDYHSNFTM-GINDAVIFNAASINKIPILAALYTDVQ +KGDVDFDKVIILQSQDVQDGTGIIRYDPEGTYTVKTLIRLMMQKSDNTAAHILGNYIIGL +DRVQTLVNAWGLTQTDMA--------------NNKTSNKDMAILMDKIFRGKIAGVALTQ +EILAFLKDSDF-EDRIPALLPKNVTVYHKVGTGT-GTVHDVGVVTQGKT-AYYIGIFSSD +IT-DEERASKLAAQVSKVVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535X3K2_9CHLR +--TLASRLDHALLGVDGQIGVAVKDLGSGRGA-VLNGDLELPAASLYKLPVLYAVFDA-- +--GLRMAEELPITDDALSYDAGTMELGAGEALSVAEALERMITISDNTSAVMLGGRV-GP +SRVNSSIAALGMNTTHYSLT------------RMTTSSLDILHLLDLLARGRAVSPAASA +DMLHLLLRQRV-NDRLPRLLPDAVRVAHKTGNLP-GTVNDVGIVYGPSA-TLAIAVLVSD +TT-DEAAAATGIARVAQAAFAYf +>[subseq from] serine hydrolase n=1 Tax=Actinomadura oligospora TaxID=111804 RepID=UPI0004BBB249 +----LRTIERAFAEAGVSGRLHAVDIDTGREL-GVGADDPVVLASVYKVPLLVAFLRLAA +RGVLDPSEQVTLRPDERTEGTGLSVMLDDVTMSLRDLACLMITVSDNAAADALYARV-GR +DEINAALEALGLRGVHVTGDGRDLFGSLDPSRTSDGTPRELTRLLSMIWRDEAAPAAECA +LMRRLLGLQVW-PHRLSSGFPDDVRVSGKTGTLLT-LRNEIGVVEYPDGGRYAVAVFTRA +SEAVAPRADAVIGTAARIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Edaphobacter aggregans TaxID=570835 RepID=UPI00068973A7 +--ALEQRLEALAAQLKGHVALYATQLNTGKTV-AVDADRPVQTASVIKLTILFEAMEEVR +AGKAHWDEKLTLQKGDGVSGSGVLTFFDTPVLTLKDVLTMMVIVSDNTATNLAIDRF-GV +DAVNSRIAWLGLKDTHLYKKVMKPATDQPKFGLGKTTAREMATVMERIGRCELAGPGEAG +QVALTMLRNQFYRNTIPRYLETGSGIASKTGSLN-AVRNDVAIVAGKSG-PMVISIFTYD +NDTADNQAEMMVARLAKEIVEAw +>[subseq from] Beta-lactamase class A n=1 Tax=Sediminibacterium ginsengisoli TaxID=413434 RepID=A0A1T4M5R5_9BACT +-kRLQAQVTALLNGFNGDVGVYVHDLQKNRVI-AVNADSVFPTASMVKMQILTGIMDKIN +RNELDYHQKIVYKDSLLYAGEDILGSFKNNEIELGKVIMLMLTTSDNTASLWLQSLAGTG +TRINELMDSLGLKVTRVNSRTAGREPNRLQYGWGQTSPREMVALMEMIVNNKVISDSVSQ +KMLRLLGRNFW-DEHAISQIPSDVFVASKNGAVD-ASRSEVLFVNGKKT-RYIFCICTKN +NKDKSNEAWVLTEKLSKLLWEYy +>[subseq from] Beta-lactamase class A n=1 Tax=Kribbella amoyensis TaxID=996641 RepID=A0A561BRC8_9ACTN +-----SRLRALFEDAGTRGWLHAIRLGSEGEV-AVDADALVPMASVYKLPLLVAFCELVD +RGALDPREQVTLEPSDRTAGPTGLSVLLDPVMSRRDLALSMMTVSDNAAADALLDVV-GL +DRLADFLSRHGLTGTRIRRGTAGNLRIYEAANASATTARDMTRLLGLIWSGEVLSAEQTA +FVRRALGLQVF-AQRLGSGFPDAVRVFGKTGTFA-ALRHEVGVVELPDGSAYAVAVFTRA +ARRKLPRVDQAIGTAARLAVD-- +>[subseq from] Beta-lactamase class A-like protein n=1 Tax=Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) TaxID=266264 RepID=Q1LEX5_CUPMC +--RVETALAPLLAGTQARVAISLR-LADGKVVlEREAERVQPSASIIKLPILFTLLEQVA +QGHLQLEQRFSLDGLERVGGTGILSQLPSVQLTLAELVRLMIVLSDNLATNALIELL-GF +EGVNDWCDRAGLGQTRLQRRMMDAAAR-AAGLDNFTSASDAAAPLCWLLRDGSLPAPLRD +FALGLLADQRE-RAHFGAALPAGAMLANKTGQLP-GLRHDAGILTVGAY-SVVLAVLADG +FTDAGGDGAQWLAEAARIVA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter lappiensis TaxID=354630 RepID=A0A1N7E4L6_9SPHI +-rKLTQQLNDAVKGFHGQVGIYVQNLKTGKTA-AINADTLFPTASMIKVSIQCGLMDKIE +KGEMQYNQKLVYRDSLLYKGEDILGSFKDKDVQLSKVALLMITMSDNTASTWLQKLV-GG +DYINNWLQQNGFKVMRVNSRVPGREAIRSIYGWGVSTPFEMCRLFTMIRQGKAVSPAASE +RMSRNMARIYW-DEKALSQIPTYVQTISKQGAVD-AAKSETVLVNAPHGD-YVFSIMTNH +NADQDNEASVLIKKISALLWHYf +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. DvalAA-19 TaxID=1839761 RepID=A0A1C4KUP3_9ACTN +----ERTIRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD +AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GS +DAVDRMCADLGLPHTRIHGGVVGTYDVYAPAYKASSTPAETARLLRAIWTDEAASPESCA +FMRAAMGTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7S030_9BACT +--ALHRTLDSLVHRFHGVLGYSINNLDTGERL-AVRGDETFPTASLIKVAILVTVYDLAE +KGMLSLDDPLTLLKIDQVPGSGVLQFHPQMTLSVRDAAVLMSILSDNTATNLLLDKV-VI +RRVWQKMEALGLPHTKVHSKVFLRIASSVKYGLGVTTPNEMARLFELMANGKAVTPKADS +AMLDILANNQD-MELMQRT-VAGLAVPHKTGATDS-VRTECALFRLQTR--VVACALTKQ +NADTDNEAQLALGKIGEAILRTw +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis rifamycinica TaxID=287986 RepID=UPI00126A688D +--------AAVFAEADARGFLHAREIGGGPEV-AVGADDPVVLASVFKIPVAVAYAREVA +AGRLDETARARVGSRYRIGGVGTAGCADDVEMSWRDLALFMLTMSDNAATDVIYHRI-GQ +AAVDRLLAGLGLGRTRLAGCCEDLFAVLDPERTTSSTPREITELLDAVWTDRAGEAAACE +QVRSMMARQIW-PHRLSSGFPAEVAVAAKTGTLP-AVRNEAGVVTYPDGRRFAVAVFTRA +NSERQPAIDAAIGKAGRLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Siphonobacter sp. BAB-5385 TaxID=1864822 RepID=A0A261Q6P7_9BACT +-tRLQKQLKTLVKDFHGDLGIYVEDLKTHSVA-AIRADTIFPTASIVKVPILLGIMDKIQ +RGQLDYHQSVTLTDSLRYKEADLVNAKTGEKIEISRLLLLMLSTSDNTASLWLQGLAGGG +LRINQVLDSLGYQVTRVNSRTPGREAIRNRYGWGQTSPREMARLFTAISERKLINPSISE +KMLRLLGRQYW-DQYALSQIPPDVFVADKHGCVNQ-SRSEVFYVAGP--HPYVCAIFTKN +NREATNEAWTLTRKISALLWKYy +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535EEQ7_9CHLR +------RLASLFAGAGVDGYLHAVDLDTGREM-RHRAGEPVVLASVVKLGVLVELFRRFD +AGEMAPEGRVRVTPAERSAGPTGLSVMKDDVLSWRDLAQLMIAVSDNAATDVITLRL-GK +DPINATLRELGLGRTVLRGTCREIYDQLSPEHGNASTAEETTRLLGLIWRDEAASPDACA +AMRRILYTQVW-PHRLSSGFGDGVRIGAKTGTLFT-WRNEAGVVELPDGGRVAVAVFTRD +HDRHNPAADAVIGSAARLAVDE- +>[subseq from] Beta-lactamase class A n=1 Tax=Thermoanaerobacter thermohydrosulfuricus TaxID=1516 RepID=A0A1I1XXX6_THETY +-qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT +DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR +DNYIKFMESLGANVIPYN--------------SNVTSPRDMSMYMENLLNYVKAHPDTAG +ELMYYLKNTIY-NDRISYTIPDEIEVAHKIGNLSN-VVNDTAIVFHPTK-PYILTVLANN +VDSDDSYAYTVIRQISKMVYD-- +>[subseq from] Beta-lactamase class A n=2 Tax=Thermoanaerobacter thermohydrosulfuricus TaxID=1516 RepID=M8CV84_THETY +-qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT +DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR +DNYIKFMESLGANVIPYN--------------SNVTSPRDMSMYMENLLNYVKAHPDTAG +ELMYYLKNTIY-NDRISYTIPDEIEVAHKIGNLSN-VVNDTAIVFHPTK-PYILTVLANN +VDSDDSYAYTVIRQISKMVYD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SB3404 TaxID=2711219 RepID=UPI0013ED0983 +---VQRALREMFADAGVRGWLHVAELHRPEACvTLDPAEPVPVGSVYKVPVMAAFCRLVD +AGALDPRRPVTLGPADRMPPTGISILRDPVTVSLRDLVALMMSVSDNTAADAVLQRVGGP +-AVDAVCRDTGMRDTHIFGGVATTLAVYDPVSKASASPADMARLLRAIWTGTVASPDSCA +FMREVMGRQPW-RHRLAAGFPDDVKVSGKTGTFG-AMRHEAGVVELADGSAYTAVVFTQA +ARADLPRADAVIGASARLAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. GLM-1 TaxID=2267691 RepID=A0A427SYK2_9PSEU +---------------GARGFLHAKEIGGGGEV-AVGADDPVVLASVFKIPVAVAYAREVV +AGRLDETERTRVGKRYRIGGIGTAGCADDVEMSWRDLALFMLTMSDNAATDVLYHRV-GQ +AAVDRVLADLGLGRTRLIGCCEDLFAVLDPERTTASTPREITTLLEAIWTDRAAEPAACE +RVRAIMARQIW-PHRISSGFGSDVKIAAKTGTLP-AVRNEAGVLSFPDGRRFAVAVFTRA +DSERQPAVDAAIGKAARLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. Aph1 TaxID=1202456 RepID=UPI00039F53B8 +---------------RSNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLALMIMASDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE +KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLITDIGYL----- +>[subseq from] Serine hydrolase n=1 Tax=Dyadobacter flavalbus TaxID=2579942 RepID=A0A5M8Q6C4_9BACT +-kKLTAMLEKALAGFHGNAGVYVRNLKTNQTA-AIHADSIFPTASMIKVPIMCGLFNKIS +KGEIKFDQELVYRDSLKYDNGIVGSFRDSTRIPLPKVVHLMISLSDNTGSLWLQAMAGGG +ATINQWLDANGFANIRVNSRTPGRKDGQAKYGWGQTTPKEMAELVAMIRNGKAINAAASE +RMYRYLGMQFW-DGEALSQIPPHIKTAAKSGAVNQ-ARSEVLVVHAPHGD-YVFCVSTKN +QQQQNNEGYTLIRKVSEIIWNHf +>[subseq from] Uncharacterized protein n=2 Tax=Streptomyces niveus TaxID=193462 RepID=V6KL92_STRNV +--------------LDARVWLHARCVDCGRGT-GHGQDEPVVLASVVKVLLALEFWRQAA +AGQLDPAERVVVRAADRLGGTGTAGFHDDARLSLRDLALLMMSVSDNTAADILFRRV-GL +DTVQALARQLGLDRAQVTGAPREVLEALDPARTTSATPREMTRLLSLVWNDRAGPAVACA +GVRDLMARQVN-GARLGAAFDRFTTVVAKSGTLP-GVRNEIGVVTCPDGARYAVAVFTRA +TSTRRPDLDAAIGEAGRGAV--- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter cerevisiae TaxID=178900 RepID=A0A149UT15_9PROT +-----QIMTKTVMKQPGHFAVYAARSGQAPDV-CLNCDDLINAASTIKLFVLDAAYEAFT +KGTLRPEDTMTVRNHSLVGGSFALYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV +LPIRSVVKAQGLNGIVFGRMIEDFDAN-DQGIRNRVSARGLGNFLQKLDSGQIVGKAQSQ +NMIQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVD-GVRNDAAIVTLPDGKRYILVVLTSD +LP-DEQAGIKVLNTLSHQAYTYf +>[subseq from] Uncharacterized protein n=1 Tax=bacterium BMS3Abin01 TaxID=2005709 RepID=A0A2H6K349_9BACT +---LMKRMSRILAGAGGDYGVYICELDTGDSF-GFNQHRPFEAASTVKIPIMMMLYGELE +AGNIGRDEVMTYLWSDYEGGTGSIQQGPGTTWTIGELATRMMKESDNVAKNMLLRRL-GY +GAVERYAHDQGAGSFDLY--------------NNRITPADMGLLLKRLYSGRVAGPQLTG +EMLSLMTGTTD-EDRLPRYLSGNISVAHKIGTMDD-TIIDVGIVRGA-GAPFIICVYSDM +VG-SEAEAEDIIGRLAWQA---- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinorugispora endophytica TaxID=1605990 RepID=A0A4R6V1M3_9ACTN +---TEERIIDLFDGADVDARLHAVDIETGREV-AARADEQVVIASMFKILLVLEFSRQAE +AGQVDPAERVTVGRADRLGGWGTAGCADDAELSLRDLAFFAMSVSDNTAADLLMRRI-GL +DTVQLLAAELGLERTRIVGGPRQVLEVLDPAHTTSSTPREMTRLLEMVWRDEAGPPRACA +AVRGLMGQQIF-WTRIASGFDAGVRIAAKTGTLPS-LHMECGVVEYPDGGRYAVSVFART +RRLERIDVDLAMGRAARAAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SID9727 TaxID=2706114 RepID=A0A6B3BEP4_9ACTN +-----TDLRAAFTDAGVTGWMHAVDIDSGAEV-DYEGHHVLSTASVHKLPLLVALHERAA +AGDIDLTELVDCPPDDRASGPTGLAAMADIALSLRDLAYLMMSISDNAAADVILQRV-GL +DAVNRTTARLGLTRTRALHSFGEMMAALDPAQSNRSTPRDLTRLLATIWRDTACTPEHCS +SIRRLMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRGEAGVVEYPDGGRYAVAVFTRT +VSAILPAADAVIGAAGRIAID-- +>[subseq from] Serine hydrolase n=1 Tax=Pradoshia eiseniae TaxID=2064768 RepID=A0A2S7MVH2_9BACI +--------DELLSVQEGNVSCVYLNLKSGETY-EYQKDMVHPSASVIKIFLMAYIYQLIE +EGAIKEEDRIAIKPETLAESSGVLYYLKDVHLSVRDLKELMIIVSDNTATNVLLGLA-GM +ESLQLYISELGYQHTLFQRRMMDFDA-VKRGFQNYTTAEETADFLKKLYLGKVVSPEASG +KMMQILREQQF-SNLVPYHLYPEQSIANKSGGLDH-VVHDAGIVLAGDA-PFVLCMFGSE +VD--VPSYSRVIQDVS------- +>[subseq from] Beta-lactamase class A n=2 Tax=Bogoriella caseilytica TaxID=56055 RepID=A0A3N2BGD5_9MICO +---LAATAAPLEAELGLTAFVHARDLDSDAQV-GLRSEDLVVTASVFKIPVLLEVCRQVA +AGERAATDRIDLGAEDFQVGTGIAAFSDPISLSLRDLYLSMMNVSDNRATDVVMDLV-GW +DRIAATLAELGMTQTVLEGDTAALFAAQDPRHSHRSTPEETTRLLGRIWNADGIDASACA +EVRRVMGMQVY-GHRLRTGFPGSVSVAGKTGTLSF-IRNEAGVVTFPDGRRYAVAVFLRH +RTADAPDLDRAIGTLGAAAV--- +>[subseq from] Serine hydrolase n=1 Tax=Siphonobacter sp. BAB-5405 TaxID=1864825 RepID=A0A2N7B5E4_9BACT +-tRLQKQLETLVKDFHGDLGIYVEDLKTHSVA-AIRADTIFPTASIVKVPILLGIMDKIQ +RGQLDYHQSVTLTDSLRYKEADLVNAKTGEKIEISRLLLLMLSTSDNTASLWLQGLAGGG +LRINQVLDSLGYQVTRVNSRTPGREAIRNRYGWGQTSPREMARLFTAISERKLINPSISE +KMLRLLGRQYW-DQYALSQIPPDVFVADKHGCVNQ-SRSEVFYVAGP--HPYVCAIFTKN +NREATNEAWTLTRKISALLWKYy +>[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2575 TaxID=2512212 RepID=A0A4R7TCJ4_9ACTN +-----GRIRAIFEDAGVRGWLHATPLDRPDESiEVDSDAVVPLASVYKLPLLVGFCQLVD +QGRLDPREQVTLLPEARTPGPTGLSLLADPIISRRDLAVLMMTVSDNAAADALLDHV-GL +DRLATILRELGLTRTRIRRGAADNLRVYEAANASSGTARELTRLLSRLWTGDLLSAGQTQ +FARTTMERQIF-QHRIAAGFPDGVRVAGKTGTFG-ALRHEAAVVTLPGGDAYAVAVLTLA +ARSDLPRVDAAIGEAARVAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter gossypii TaxID=551996 RepID=A0A1G8FUC3_9SPHI +-sKLTAKLNEAVKDFQGQVGIYVHNLKTGKTA-EINADTLFPTASMIKVSIQCGVMDKIE +KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GG +EYINNWLNQNDFKVMRVNSRVPGREAIRKIYGWGVSTPREMCRLFAMIREGKAVSPAASE +RMYRNMGRIYW-DEHALSQIPPYIHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH +NKTPDNEAGLLIKKVSALLWHYf +>[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Thermoanaerobacter thermohydrosulfuricus TaxID=1516 RepID=UPI0009438495 +-qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT +DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR +DNYIKFMESLGANVIPYN--------------SNVTSPRDMSMYMENLLNYVKAHPDTAG +ELMYYLKNTIY-NDRISYTIPDEIEVAHKIGNLSN-VVNDTAIVFHPTK-PYILTVLANN +VDSDDSYAYTVIRQISKMVYD-- +>[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Thermoanaerobacter TaxID=1754 RepID=UPI00052668E7 +-qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT +DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR +DNYIKFMESLGANVIPYN--------------SNVTSPRDMSMYMENLLNYVKAHPDTAG +ELMYYLKNTIY-NDRISYTIPDEIEVAHKIGNLSN-VVNDTAIVFHPTK-PYILTVLANN +VDSDDSYAYTVIRQISKMVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CNZ287 TaxID=2572908 RepID=A0A559VQB8_9ACTN +hrTARSRIRRVFAEAGVTGQLHARDIDTGAEL-AVAADTPVSTASVHKVCLLATLYREAE +HGRVDLTAAVDIPAGGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI +EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLTAVWRDEVCTGAYAA +DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAGRLAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=A0A433L0J2_CLOPF +------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE +EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM +DKINKTIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSECSFLSKENSQ +MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG +IPNS-VYGTVTLAKSGKMTWD-- +>[subseq from] serine hydrolase n=1 Tax=Acetobacter cerevisiae TaxID=178900 RepID=UPI0009EE77C2 +-----QIMTKTVMKQPGHFAVYAARSGQAPDV-CLNCDDLINAASTIKLFVLDAAYEAFT +KGTLRPEDTMTVRNHSLVGGSFALYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV +LPIRSVVKAQGLNGIVFGRMIEDFDAN-DQGIRNRVSARGLGNFLQKLDSGQIVGKAQSQ +NMIQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVD-GVRNDAAIVTLPDGKRYILVVLTSD +LP-DEQAGIKVLNTLSHQAYTYf +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0008A2FD41 +-qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAVA +NGRYALEQPLALPAGDRAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] serine hydrolase n=1 Tax=Hamadaea tsunoensis TaxID=53368 RepID=UPI00048A333C +---IEHRIAALFADAGAIGRLHAVDIDTGRQV-AVAADEPVAIGSVFKLPLVVALHRLAD +AGVLDLTEAVTLATGRTSGPTGIGAMRDPVTMSLRDLAHLAVSVSDNAAADAIADRI-GL +PAVAETLARLGLAGTAVTQLCRDIAETLDPGRTNRSTARDCTTLLTAVWRDTAAAPSSCS +AVRRLLSLQVW-PHRLAAGFPDDVRVYGKTGTLPT-IRNEVGVVEYPDGGRYAVAVFTRS +ASLALPRVDAVIGTAARTAVQY- +>[subseq from] Beta-lactamase class A n=2 Tax=Kibdelosporangium aridum TaxID=2030 RepID=A0A1W2EYN4_KIBAR +----------------------------SREV-DVDADEPVVMASVYKLPLLVALCRQFD +AGRIDPRRTVRINPASCSPPTGIATFLDPITMSWRDLAVSMMTVSDNAAADLILGEV-GL +DTVGSTLADLELTGTKIVGGAADVEAAYDPAYTSATTPRDMTRLLSLIWSDSVASAEQCA +FIRRLMGMQVW-QHRIRAGFPGDVRVSGKTGTIG-AVRNEVAVVEYAHETPIAVAVFTFA +ARSDLPAVDAAIGEAARIAV--- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus opacus TaxID=37919 RepID=A0A2S8IQM8_RHOOP +------------------------------DI-AVGADDLVVLASVYKLPLLVALCRAFE +SGELSPTATVRVNPADCTPPTGVSTFRDPVVLSWRDLAMSMMTVSDNAAADLVLGQV-GL +ASVERTLSELGMTNTRIIGGTADSHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE +FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGEIPVAVAVFTRA +ARTDLPVVDAAIGHAARIAVT-- +>[subseq from] Serine hydrolase n=1 Tax=Echinicola sp. LN3S3 TaxID=2591634 RepID=A0A514CK23_9BACT +-kKLSKALYSLMEDFKGTAGVYVEHLPSGKFA-AINADTIFPTASIVKVPILIGVFDKID +RGELEYHQPLVYRDSIRYGGSGLMQFFEDSTTDLSTLLALMITYSDNTTSLWNQALAGGG +ETINPIMEKYGMEFTRVNSRTPGRKGDWEKYGWGQTTPREMATLLKKIRKGEMISKVASE +RMYRLMTNVYY-DDYALSQIPPYVQTAAKQGMVN-ASRSELVMVNAPHGD-YVFYIATKN +NQKPDNESWVLARKVSAFLWEYf +>[subseq from] serine hydrolase n=1 Tax=Acetobacter persici TaxID=1076596 RepID=UPI000472C323 +---LAQRVAETVADQPGHYAVYAARSGQAPDV-CLNCDDLINAASTIKLFVLDAAYAAFA +KGTLHPDDTLTVHNRSLVGKGHFAYAQAGKAVPVSELLRVMIQYSSNLATNLMIEKL-GV +LPVRSVVNAQGLNGIIFGRMIEDFDAD-AQGIRNRVSARGLGNFLQKLNNGQIVGKTQSQ +SMIGIMLGQKF-NDIIPPGLPAGTPVAHKTGWVN-GVRNDAAIVTLPDGRQYILVVLTSG +LP-DEQAGIKVLNTLSHQAYLYf +>[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. MYb45 TaxID=1827294 RepID=A0A2S9BQB6_9MICO +------------------------GAEGGPEV-SVDADEPVVLASVFKILVLTAYVRAVA +AGELDPTERTTVTARYRIGGVGTAGFSDDVEASWRDLAQNMMTMSDNAATDVVYHRL-GS +DAVNRVISDLGLRHTRLVGCCEDLFAAVHPAKTSHSTPRDVTTLLNALWTDTAATAEACR +QARDIMAQQIW-PHRLSSGFPPGVRIAAKTGTLPT-WRNEAGVVTYPDGRQHAVAVFTRA +ASLA-DRQ--------------- +>[subseq from] Uncharacterized protein n=1 Tax=bacterium TaxID=1869227 RepID=A0A2E4FZ88_9BACT +------QVATIIQPVSSNISLVVTHLGTNYTY-SWRPNQRYNPASLIKLPILACLYNRVA +SERASLSNTLMHRARHTQSGAGILKHARPGEYRLDTLANMMMRYSDNTATLMLIEYL-DR +QQINDYMRRIGMQNTWLKN--PHLTQP---PQSNQTTAMDIHQLLVQLARYELLSPTHTY +ELLSQMRQQIY-RWGIPHWLPPSFSVANKTGTLGS-VRHDVGLVIHNKD-AYVVSILTEG +LPK--GTRAATIARIAEAIL--- +>[subseq from] Serine hydrolase n=1 Tax=Sporosarcina sp. BI001-red TaxID=2282866 RepID=A0A3D8Z212_9BACL +--QLKQELQRISSDASGAVSLYASTPD-G-PI-AICPDEVQRSASILKVPIAMACLAAAD +RGEIDLDAQLKIEE--PVGGSGVLAYMTDMDMTLRNALTLSIIVSDNTAANLVIEYV-GL +ERIQAFFRQVGAEHSLVSRKFMDYD-ALAKGLENVATARDMVRFLACLDPSEFLSLTSKQ +QLKTIMRDQQL-IDKLPAYQPETLIIGNKTGTLP-GVEHDIAYFEKGNR-RVDIAVLTSN +WDYN-HDGQKTIAQIGKAIIEY- +>[subseq from] Serine hydrolase n=2 Tax=Actinobacteria TaxID=1760 RepID=A0A329R3H1_9ACTN +-------------------------TAGLAEV-NVDADARVVLASVFKIPFAVAYAREAA +AGGLDPAERTTVTARDRTGGVGTAGCADDVEMSWRDLAMFMMTMSDNAATDVLYRRL-GY +RRIQAVLDDVGLHSTNIIGCCEDLFAVLDPARTSASTPRDLTTLLAAIWTDEAGPPEACD +EVRSIMAHQIW-PHRLTSGFPGDVQVAGKTGTLP-AVRNEAGVVTYPDDQSYAVAVFTRA +ESLDQPRIDAAIGQAARLAVEH- +>[subseq from] serine hydrolase n=1 Tax=Jiangella gansuensis TaxID=281473 RepID=UPI0004ADD4A3 +--RLRAGLASLAEAGPGRWAFAVWE--QGRPVvSLSGAEPVPAASTIKVPLLVLALQDVA +TGRRDLDDDVPVPA-ERAGGAGVLRLLPSVRLRFAELLTLMIAVSDNAASNLVIELL-GL +DDADRRLAALGLTGTRLRRRLMDTEAA-RAGLENVTTADDQSRLLDRLAGPDLLPAPLRA +FALDALAEQQV-NDRMPTQLGDDVRCLHKTGELP-GVRHDVGLLEFDGRT-VALAALGTE +LTDPA------------------ +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. OF03-6AC TaxID=2292356 RepID=A0A396LJT6_9FIRM +--TLEKRIAAELYCYQGKMSVFVDDL-QGHTV-EVGADEEFETASTIKAFILAALYLQAQ +RGKADLAEEITYEQSQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFAHTVLHNPLHF-DR---YRRLGTTTPRDYAALFARIAKGELVSREASA +EMLAILRQQHY-NTMLTHDFPQYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Deminuibacter soli TaxID=2291815 RepID=A0A3E1NR37_9BACT +-kKLEKLLGEALQGFNGESGIYVHDLNHNRVA-AIRADSLSPTASMVKMTILTGIMDKIH +RGELDYHQQLVYKDSLLYAGSDILGSFKSDEIELSKVIMLMLTTSDNTASLWLQSLAGGG +TRINAILDSIGFTATRVNSRTPGREANRQQYGWAQTSPREMAGLMEKIVQHQLVSDSLSE +RMLRLLGRNYW-DEEAISVIPSDVFVASKNGAVD-ASRSEVLFVNGRGR-RYIFCICTHN +NKDTGNEAWVLTRKISKLVWDYy +>[subseq from] Beta-lactamase class A n=2 Tax=Jonquetella anthropi TaxID=428712 RepID=H0UJN2_9BACT +--RVASQIANRVYESGVQASVVLADPATGEQF-DLRGLQRLKSASLIKLPILWDLFARAE +EGSLNLSETIVVPSEKRVDGGLLHKFSASPTLRLEDLAVLAGTVSDNTAANLLMDRL-GL +DGINDRIRSLGMKSTSLERRMLDSGAA-KAGKDNWTTACDVALFLSALTSTAGLSEAGKR +RIIDILSAQKL-QSKLAGAIPCDKVLAHKTGELP-GHEHDAGIFFPFGPRPAVLVVLTTG +LT-DRLDGVRFCSALGRLVYDEw +>[subseq from] Beta-lactamase class A n=1 Tax=Asanoa hainanensis TaxID=560556 RepID=A0A239GCY8_9ACTN +------RIAGIFAAVGVDAQLHAVDIDRGTQL-SVRADERVVLASIFKVLLVLEFARQAA +AGQLDPTERVLVRAADRLGGWGTAGCADDAELSLRDLAYFAMSFTDNTAADLLLRRV-GP +DVLPLLAAELGLTSTRITGGPRELLEVFDPDQTTSSTPREVTRLLELIWRDEAGPPAATA +MVRGLMARQIF-FTRIASGFPNGVRVSAKTGTLP-GLHMEAGVVEYPDGGRYALAIFARA +HQLDFRRVDLAMGEAARTAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Faecalibacterium cf. prausnitzii KLE1255 TaxID=748224 RepID=E2ZF83_9FIRM +--TLEKRIAAELYCYQGKMSVFVDDL-QGHTV-EVGADEEFETASTIKAFILAALYLQAQ +RGKADLAEEITYEQSQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFAHTVLHNPLHF-DR---YRRLGTTTPRDYAALFTRIAKGELVSREASA +EMLSILRQQHY-NTMLTHDFPQYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. 14C53 TaxID=2508997 RepID=A0A5C4J3S1_9ACTN +---VAERVEAEFRDAGVTGFLHAVDMDTGREV-AVRADAPVVLASVFKVPLLVTFHRQAA +EELIDPSEQVTLPAAGRTTPTGVSGMLDEARMSLRDLTFMMITVSDNAAADVVLERV-GR +DAVNATSAALGLRDTVVEVSGRELHEALDPARTSRSTPRDMTRLLSMIWRDEAAPPPGCA +AMRRLFGLQVW-PHRLSSGFPDAVVVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +PLAVLPRADAAIGTAARIAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Cryosericum septentrionale TaxID=2290913 RepID=A0A398DRV2_9BACT +-qDWQEQVRALLGGAQGKFGVYAAT-LTVPLF-EYQTSSVFPSASTIKVLIMAELLRQVE +AGTHALTEHP-VLPTAPTGGCGILEFLSSDYPDLMDLLHFMICSSDNKATNVLIRLT-GM +DAVNQLAVDIGMTNTRLRRFMMDTESV-QQDIDNTTSPADMGRFFKLLACNELVSSRASA +TMKTILGHQQF-ADIMMLFLPEGIRAEHKTGGLP-GSVLDVGLVYGA-RDPLILCLMATQ +LAN-NGEGAVILGKVAAITYT-- +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. F01003 TaxID=2305909 RepID=A0A444MIK8_9SPHI +-kKLTAQLQTALQGFNGQAGIYVQNLKTGKTV-AINQDTLFPTASMIKVSILSGLMDKIE +KGELKYNQKLAYRDSLLYAGEDILGSFKDKDIMLSKVAMLMITMSDNTASLWLQKLVTG- +THINNWLDSNGFKNMRVNSRTPGREAMRKIYGWGVTTPYEMCKLFTMIRNGQVVSPAASE +RMSRTLNRIYW-DNTALSQIPPYVQCLSKQGAVDE-SRSETVLVSAPHGD-YVFSIITKN +NKVTDNEAYVLIRKVSALVWHYy +>[subseq from] Beta-lactamase class A n=1 Tax=Lechevalieria fradiae TaxID=200378 RepID=A0A1G7VA29_9PSEU +--------------AQGFVHVREVGVENGPEV-GLGADDPVVLASVFKIPVAVAYAEEVA +AGRLDETGRTRVTSRYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDAVFHRV-GQ +AAVDAVLARTGLVRTRIMGCCEDLFAILDPERTTSSTPREITTLLDAVWTGRAASPRACE +TVRSIMSRQVW-PHRLASGFGSDVQVAGKTGTLPT-LRNEAGVLTYPDGRGYAVAVFTRA +SSPDQPAVDAVIGRAARLAVDH- +>[subseq from] Uncharacterized protein n=1 Tax=Armatimonadetes bacterium Uphvl-Ar1 TaxID=2004467 RepID=A0A1Y0GW34_9BACT +---LKKQMDEVAAGFRGRLGYHVIDLKTGQRF-GFRDGERYPSASTIKTVVMIELFNQIE +EGKMSFEDKLEVPPVGQRNPSMWTAHLIEGTVNLDGLNSLMMNVSDNTATVMLSQHV-GI +QNIEKRMLGWGFENTACTIRTAGKGERLERLYQGVTSPVEMASILKMIHDGKAASPAACE +KMIRIMSSQYW-DDFIDWSVPSDVVIASKVGALQR-SRSDSAIVYGP--RPYILTIYTDN +AT--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium TMED177 TaxID=1986677 RepID=A0A1Z9JE80_9CYAN +-----------ATQKDLQASAYMLVLDDGRFA-QMNGDRPMPAASSIKTPILLAALERID +EGDLHWNEPLVLTKELVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLLIERVGGK +EEINTKFQELGLTATVVNNWLPDLDGT------XTTSARDLSRSIAIVDTGETLSPRSRD +LFREVMSTSVT-NTLLPTGLMQGYAVLNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG +PFN-DPRSTNLIRAMAKAMA--- +>[subseq from] Beta-lactamase n=2 Tax=Acetobacter TaxID=434 RepID=A0A252EGX0_9PROT +---LAQSISKTVKAQPGHFAVYAALSGHCPAV-CLNCDDLINAASTIKLFVLDAAYDAFT +KGTLHPQDTVTVHNRSLVGTGTFAYAQAGKPVPVSELLRVMIQYSSNLATNLMVEKL-GV +MPIRSVVKAQGLDGIVFGRMIEDFDAN-DKGIRNQVSARGLGAFLQKLDNGQIVGKAQSQ +SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGKHYILVVLTSD +LP-DEQAGIKVLNTLSQQTYTYf +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF2E528 +------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGILRALPRLTIKVEELLTLRIIVSDNTATNEFISLV-GF +EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE +KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVILIDG +LS-DNEQGRRLIADIGYL----- +>[subseq from] Uncharacterized protein n=1 Tax=Streptomyces niveus NCIMB 11891 TaxID=1352941 RepID=V6JHZ6_STRNV +----RDRIRAAFAAAGVTGWLHAVDIDSAAQI-EVGADQPVVTASVHKLCLLVALHQHAE +AGRLALTDQVESPADGRTPGPTGLSAMLDPAVSLRDAAYLMMAVSDNTAAELLLARV-GL +DAVNETTERLGLRRTHAVQTFGEFITALDPARTNRSTPRDMTRLLGAIWRDEACTPEHSA +AVRRLLGLQVW-PHRLASGFPDEVHVAGKTGSAPT-LRNEVGVIEYPDHGRYAVAVFTRA +ASAALPAADAVIGTTARIAID-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. 278922_107 TaxID=1292019 RepID=UPI00048D8EFE +----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIGAFRQID +EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIMVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMD-ETAVKQGSDNYTCASDVVKCLKEICEGNFLRKSSCE +KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLITDIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. QHH-9511 TaxID=2684468 RepID=UPI0013193665 +---VRTRITAAFTDAGITGQLHAVDIDTGASH-GIDADTLVPTASVHKLCLIATLYRQAA +LGRLDLRQPLDIPAEGRSPGAGLAAMRDAARLSLRDLATLAVAVSDNTAADLLFDTL-GL +DTVNQCMADLGLTRTVARHTMRELYAALDPARTNHSTPREITGLLTAAWRDDICPQEYAE +ELRTVLGLQAW-SHRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA +AAVTLPAADAAIGRAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V2RJJ4_9BACT +-eDLQQKIEQRIKEFGAEVGIYYEK-PDGSIF-THNADAIYHAASTMKVPVMMEVFREVE +TGELSLDQKMKIMNESIVDGSKFSYNWIGKEKPLRELLERMITRSSNLATDLIIGLV-TP +EKVRALMTKIGAKDMYVLRGVEDIK-AYQAGKINTTSAHSLAICMKELMDPKLFSESSRN +EMFEILTHQEF-RKGIPKGIHSDLIIANKTGDLTE-INHDAAIIRDSKGATSILVILTRG +VK-DDAKGKELIAVLAGDIWD-- +>[subseq from] Beta-lactamase class A-like protein n=4 Tax=Microgenomates group TaxID=1794810 RepID=A0A0G0QSE6_9BACT +--RVRREFKEKTKNLSGVYGLFVIHLDNGFSY-GVNENETFTAASLIKLPVMAEMYIEME +DGRLRMEDRYTLKNSDKVAGAGSLYGKPAGYITYRNLIQLMGKQSDNTAFNICRKLL-GD +EKIDEVIRSVGMVDTSLEK--------------NETTPKDIGIFFEELWKGNIVSEESRD +EILGALTDTIY-EDWLAAGIPEGIRLAHKYGREVH-VVNDAGIVFTD--RPYVVVIMSKG +VV--EREADEIFPELAKLVYE-- +>[subseq from] Beta lactamase n=2 Tax=Rhodococcus TaxID=1827 RepID=Q0SKC5_RHOJR +------------------------------DI-AVGADDLVVLASVYKLPLLVALCRAFE +SGELSPTASVRVNPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL +ASVERTLSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE +FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA +ARTDLPVVDAAIGHAARIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Lechevalieria fradiae TaxID=200378 RepID=UPI000B7C7482 +--------------AQGFVHVREVGVENGPEV-GLGADDPVVLASVFKIPVAVAYAEEVA +AGRLDETGRTRVTSRYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDAVFHRV-GQ +AAVDAVLARTGLVRTRIMGCCEDLFAILDPERTTSSTPREITTLLDAVWTGRAASPRACE +TVRSIMSRQVW-PHRLASGFGSDVQVAGKTGTLPT-LRNEAGVLTYPDGRGYAVAVFTRA +SSPDQPAVDAVIGRAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces spinoverrucosus TaxID=284043 RepID=A0A4Y3VL86_9ACTN +------RVRAAFAEAGVTGWLHAVDIDTGAQL-DAGADQPVCTASVHKLCLLVTLHELAD +TGDLDLTEQVDCPPLGRTPPTGLAAMRDPVRMSLRDLAYLMTAVSDNTAADLLLGRV-GL +DAVNRTTARLGLTRTHAVHTFGELLAALDPARTNRSTPRDMTRLLSAVWRDEACAPEHAA +AVRRLLGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT +ANATLPAADSVIGTTARLAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Thermoanaerobacter siderophilus SR4 TaxID=880478 RepID=I9ACE5_9THEO +-qELKNNIQALISRYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT +DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR +DNYIKFMESLGANVIPYN--------------SNVTSPRDMSMYMENLLNYVKAHPDTAG +ELMYYLKNTIY-NDRISYTIPDEIEVAHKIGNLSN-VVNDTAIVFHPTK-PYILTVLANN +VDSDDSYAYTVIRQISKMVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TMED290 TaxID=1986700 RepID=A0A424PC02_9BACT +--------------------------DDGKSI-LINENEFFHAASTMKTPVMIEFFKKIN +EGKISSDDSLLINNESIVDGSKFEYENLGKYISTDKLVYDMITRSSNFGTNLLIDYL-NV +EDVNNTMKNIGAKNMKVLRGVGDLKA-FDLGLSNSTTAADLLIIYEKLAMGEIVNNESSN +KMIRILKDQVY-NDIIPKYLPENVEVAHKTGWIS-GVRHDSGIVYVGNNKKYILVLLSKN +LE-DDVEGADFLAKISLEIYN-- +>[subseq from] serine hydrolase n=1 Tax=Cupriavidus malaysiensis TaxID=367825 RepID=UPI0008A6AACD +--RVEAGLAPLLAATPARVALSLR-LRDGSIVlERAASCAMPSASLVKVPILLAMLEQVG +QDRLRLAQEMSLAGIERVGGTGILAQLPSVRLTLAELARLMIVLSDNVATNALIALL-GF +DAVNGWCERAGLAQTRLQRRMMDAAAR-AAGRDNFTSAGDTAAALGWLLRGDTLPAPLRA +FGLALLADQRE-RAHFGAALPAAARLANKTGQLP-GLRHDAGILTVGDQ-SVVLAVLADG +FTDPRTARE-------------- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. 12(A) TaxID=1163671 RepID=UPI000466C3B6 +--TLEKRIEAEIKSYDGIMGIYLDDL-RGTVI-QIKADETFETASAIKTWILACLFWEAE +NGRACLEDQIEYKKEHWVDGSGVLGALEPGALRVRDAATFMMIVSDNIATNMMIDYL-GL +DRINQCIRRLGSMDTVLHNPIHFDQ----YERLGTSTPRDYASIFIRLVKGELISPEADR +QMVEILKKQQY-QSMITKDFPPYISVASKSGSMD-ACRNDGGIVFTPYG-PYVIVMFHKE +FSYPAHPATMFGARVSRLILDQy +>[subseq from] serine hydrolase n=1 Tax=Nakamurella lactea TaxID=459515 RepID=UPI00048EBFCA +-----------AARAGADVFAHALDIDSGAEV-GINSDHPVVTASVFKVPVLTEYVRQVS +SGELDPNARVTIRAGSATIGPTGLSVFSDDTWSLRDVATSMITVSDNGATDIVTGMV-GV +DRVNATMRSLGLPSTALIGDCAALFAVCTPERTNRSTPRESARLLQLLWTDQAAGPAACA +EARRILGLQIW-PHRLSSGFPDDVKISGKTGTIGI-VRNEIGVVEFPDGHRYAVAVFTRS +HAYRQPAVDALIGTVAAALVD-- +>[subseq from] serine hydrolase n=1 Tax=Senegalia massiliensis TaxID=1720316 RepID=UPI0013EF5810 +-------LESIINEDKLKYSLYVEDLKTNKIIfDINSDAEVTSASMIKIFIMAEAYSQIS +KDEFMSQKIVNVDRDNIVGGSLIKN-LSNYCYSIKDLIFLMMNLSDNTATNQLIDIL-RI +ENINKFISEEGLKNTVINRKMMDFERK-KKGFDNITSSRDIAHILKKIYYKDLIDKDASV +NMMNIMKKQMDNRMMARNIDKSNTKIYHKTGNIPY-TNHDAGIVIFKDIE-YLF-VMLTW +DAYDNIYGRKVIGEVSEKIYNDf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNY243 TaxID=1169161 RepID=UPI00036C340B +hrTARSRIRRAFTEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE +HGRIDLTTVVDIPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI +EAVNGTMAALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA +DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAARLAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Armatimonadetes bacterium Uphvl-Ar2 TaxID=2004468 RepID=A0A1Y0H8I5_9BACT +--TIEPQVRAVAERFRGRLGYHIQDLTTGEVI-AHRSTERFPSASTIKTVLMFEAARQID +KGELTWDTTVPLPPVAERNSSQWAYYLREGLINVDALTNLMMNVSDNTATVVLGEKL-GL +LRINQTLQEMGYQDTAYTVRVPETETRRQFANMGVTSPQEMARFLLMIDRGGVLSEAAHD +RMRRILAKQYW-DDWVMGTVPSDVVVLSKVGALNR-HRSEIAIVKGP--RPYLVAIYTDN +QADQENEGDQAIIRIGTLLWNH- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. Tu6071 TaxID=355249 RepID=UPI00031B1C5E +--AVADRIAAAFADAGVDGVVHAVDIDRGTET-GWEADRLVCTASVHKLCLLLALHRLAA +AGRIDLTERVECPVEGRTPGTGLAAMLDAPRMSLRDLAYLMIAVSDNAAADLLLARI-GL +EEVNRTTEALGLRRTRAVESFAATQEALDPAHGNRSTPRELTRLLAALWRDEFLPEPHGA +AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA +ADHVVPAADAVIGVVGRIVVD-- +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter rubeus TaxID=2027860 RepID=A0A364WUS7_9SPHI +-sKLTAKLNEAVKDFQGQVGIYVHNLKNGKTA-EINADTLFPTASMIKVSIQCGVMDKIE +KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GG +EYINNWLNQNDFKVMRVNSRVPGREAIRKIYGWGVSTPREMCRLFAMIREGKAVSPAASE +RMYRNMGRVYW-DEHALSQIPPYIHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH +NKTPDNEAGLLIKKVSALLWHYf +>[subseq from] Serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A179TAF6_ALCXX +-qHVDAALTPLLAATPARISLSLRDLDGGVVL-ARHADRMQPSASIIKVPILLALLEAVA +NGRYALEQPLALPASDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWNQRANLEATRLQRRMMDAAA-REAGRDNYTSAGDATAALCWLLRDDTLPAPLRA +FALDVLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FT--------------------- +>[subseq from] serine hydrolase n=1 Tax=Anaerocolumna aminovalerica TaxID=1527 RepID=UPI000BE47DF1 +--TLEERIKAELASYNGTMGIYVNDF-QGNKV-EINIDEEFETASTVKTFILGTLFDEVE +KGNKNLSDKLIYTQENEIEGSGILRSLDYGVLTVKNVATLMIIVSDNIGTNMMIDYL-GI +DTINAFMQSYGFTHTKLHNKIN---FD-IYDKLGTTTPRDYGKIFEMICKEELISPEASR +QMLEIFKKQHY-NSMLTKSFPQYIYVASKSGSMD-ACRNDGGIVSTPYGK-YVIVLFNKN +FTDPEHQATVFGSKVSRLIFDQy +>[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Thermoanaerobacter siderophilus TaxID=106578 RepID=UPI000586F9AA +-qELKNNIQALISRYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT +DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR +DNYIKFMESLGANVIPYN--------------SNVTSPRDMSMYMENLLNYVKAHPDTAG +ELMYYLKNTIY-NDRISYTIPDEIEVAHKIGNLSN-VVNDTAIVFHPTK-PYILTVLANN +VDSDDSYAYTVIRQISKMVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. IB2014 016-6 TaxID=2517818 RepID=A0A5C8Q918_9ACTN +--------------LGARLWLHARCVDCGRAA-GHAEDEPVVLASVVKVLLVLEFFRQAV +AGQLDPAERAVVRAADRLGGTGTAGFHDDVELSLRDLALMTMSVSDNTAADILFRRV-GL +DTVQALARQLGLERVRVTGAPREVLEALDPARTTSATPREMTRLLSLVWNDRAGAAAACA +GVRELMSGQVN-GARLGAAFDRFTTVAAKSGTLP-GVRNEIGVVTYPDGARYAVAVFTRT +ASTRRPDLDAAIGGAGREAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A651HVD8_9BACT +-----------EEGDSIHIGIAVLDMETGRSL-EMNAERVFHAASTMKVPVLLEWYRQSE +LGIRSLDEGVRVHNRFRSVGSEVLDEDVDEGLPARRIAEGMIQVSSNLGTNILLELL-TA +DSVQATMARIGAPEMQVLRGVSDIPA-FEAGLSNRTTARAYLRVLEAIARCEVTSQASCD +EMMEILEGQEF-RSEIPAGIPAGTRVGNKTGSITR-ILHDGAIVQPTGRAPYLVVTLSEG +YE-DKDHGSRTLSDLSGIIWD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces silaceus TaxID=545123 RepID=UPI0006EB9913 +-----------FAAAGVTGRLHALDIDSGAEV-DAGADQPVVTASVHKLCLLVTLHEQAA +AGVLDLTEQAECPVEGRTPGPTGLAAMLDPVMSLRDIAFLMMSVSDNTAADLLLERV-GL +DAVNATTARLGLERTHATHAFRELLAALDPARTNRSTPRDMTRLLRAVWRDEACAPEHGT +AIRRVLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVIEYPDGGRYAVAVFTRA +AGAILPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CA-128772 TaxID=2073159 RepID=UPI000CD31B36 +---------------------HAREIGGGPEV-AVGADDPVVLASVFKIPVAVAYAREVA +AGRLDETARTRVGPRYRIGGIGTAGCADDVEMSWRDLALFMLTMSDNAATDVVYHRV-GA +EAVDRVLTDLGLRRTRLIGCCEDLFAVLDPERTTSSTPREITELLDAVWTGRAGDPAACE +RVRSMMARQIW-PHRLSAGFPSDVAIAAKTGTLP-AVRNEAGVVSFPNGRRFAVAVFTRA +DSERQPAVDAAIGRAGRLAVDH- +>[subseq from] Beta-lactamase class A n=2 Tax=Acidipila rosea TaxID=768535 RepID=A0A4R1LDH7_9BACT +--ALEAQLQTMTAGYHGKVALFAKDLTTGQTV-ALNADTPVQTASVIKLTVLYDALQQVR +AGRVHFDDKITLTKQDQVQGSGVLMFFDTPLLTLKDVLTMMVIVSDNTATNLAIGHL-GL +KNIDDEIVALGLKNTWLYKKVFAPAESMPADQTGKTTPREMASVMQRYVDSTAAKTAEDE +QLCGHMLKNQFYRDSIPRYLEKDSAIANKTGALD-AVRNDVGVVYAKSG-PIVLSLFTYD +NKDQDNEGEVLMAHLAKTIVDKw +>[subseq from] Beta-lactamase class A n=1 Tax=Gordonia sp. KTR9 TaxID=337191 RepID=J9REM7_9ACTN +--------RETFTDAGCSGCVHARTIGTPVEF-SHDADAPVVLASVYKLAVLISLCRLAD +RGDIDLAASITVEPTRWAQGPTGLALFTDPVMTWRDLATSMMTVSDNVAADVILTHI-GL +PRIHADLNQLGLTHTRIVGGVAELHEAYDAAYSSSATPRDCTTLLDAIWTDRAASAASCE +FIRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AVRNEVGVIEFPGELPVAIAVFTMS +ARSELPEVDRAIGEVARAVVT-- +>[subseq from] serine hydrolase n=1 Tax=Senegalia massiliensis TaxID=1720316 RepID=UPI00102FA12E +-------LESIINEDKLKYSLYVEDLKTNKIIfDINSDAEVTSASMIKIFIMAEAYSQIS +KDEFMSQKIVNVDRDNIVGGSLIKN-LSNYCYSIKDLIFLMMNLSDNTATNQLIDIL-RI +ENINKFISEEGLKNTVINRKMMDFERK-KKGFDNITSSRDIAHILKKIYYKDLIDKDASV +NMMNIMKKQMDNRMMARNIDKSNTKIYHKTGNIPY-TNHDAGIVIFKDIE-YLF-VMLTW +DAYDNIYGRKVIGEVSEKIYNDf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. 4R-3d TaxID=2559605 RepID=A0A4Y8Y1N1_9ACTN +----RDRIRAAFAAAGVTGWLHAVDIDSAAQI-EVGADQPVVTASVHKLCLLVALHQHAE +AGRLALTDRVESPAGGRTPGPTGLSAMLDPAVSLRDAAYLMMAVSDNTAAELLLARV-GL +DAVNETTERLGLTRTHAVQTFGEFITALDPARTNRSTPRDMTRLLGAIWRDEACTPEHSA +AVRRLLGLQVW-PHRLASGFPDEVHVAGKTGSAPT-LRNEVGVIEYPDHGRYAVAVFTRA +ASAALPAADAVIGTTARIAID-- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=A0A2C5HKL9_9BACI +----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIGAFRQID +EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIMVSDNTATNELISLV-GF +EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE +KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG +LS-DNEQGRRLITDIGYL----- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. (strain ATCC 39116 / 75iv2) TaxID=385957 RepID=UPI0002E7C7C9 +------------EAAGVRGWLHARCLDCGGET-GHHPDEPVVLASVVKVPLVLELARQVA +AGQLDPADRLRVTAADRLGGTGTAGCADDVEMSLRDAAFFALSVSDNTAADLLFDRV-GL +DNVRSLLRELGLADTRVIGSPRDVVAALDPLRTSASTPRDMTTLLAAITGDTAGPPEACG +WVRQLMGQQVN-WHRLTAAFPPQVRVWGKTGSLL-AVRNEIGVAEYPGGERYAVAVFTKA +PTSRLPDVDHAIGEAAKAAIE-- +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. AM43-5AT TaxID=2302957 RepID=A0A3A6EC57_9FIRM +--TLEKRIAAELYCYQGKMSVFVDDL-QGHTV-EVGADEEFETASTIKAFILAALYLQTQ +RGKADLAEEITYEQSQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFAHTVLHNPLHF-DR---YRRLGTTTPRDYAALFARIAKGELVSREASA +EMLAILRQQHY-NTMLTHDFPQYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces niveus TaxID=193462 RepID=A0A1U9R0C9_STRNV +-----DRIRAAFADAGVTGWLHAADIDSGAQI-DVGADRSVVTASVHKLCLLVALHEHAE +TGRLNLTDQTECPRDGRTAGPTGLSAMLDPALSLRDAAYLMMAVSDNTAADLLLERV-GL +DAVNGTTERLGLTRTHAVQSFRDFIAALDPGRTNHSTPRDMTRLLGAIWRDEACVPEHGA +AVRRLLALQVW-PHRLASGFPDDVHVAGKTGSAPT-LRNEVGVIEYPDRGRYAVAVFTRA +ASATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 01375 TaxID=2203194 RepID=UPI000F77045F +-----AEIEAVFANAGARGFVHAREVGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVA +AGRLDDTERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ +EAVDRVLTDLGLTRTRLIGCCEDLFAVLDPERTTASTAREITTLLDAIWTDRAGDPAACE +RVRAIMAQQIW-PHRISSGFPAGVTIAAKTGTLP-AVRNEAGVVTDVDGRRYAVAVFTRA +ESDRLPAVDSAIGEAARLAVAH- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Amycolatopsis sp. YIM 10 TaxID=2653857 RepID=A0A5P9PY03_9PSEU +----------HFEAAGVRGWLHARRLDTGAEC-GWGADEPVVLASVVKVPLVLEFARQVA +AGQLDPRDRVRIGARDRLGGSGTAGCADDVELSLRDAAYFAMTVSDNTAADVLCDRV-GL +DNVRSLVRELGLARTRIAGAPRDIVAALDPGWTNASTPREMTALLGHLWTDQG---EPAA +QVRQWMGQQVF-WSRLGGAFPPEARVWGKTGTLPC-IRNEIGVVEYPDGARFAVAVFTRS +ALQRQPAVEQAIGAAAAAAV--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. WAC 06738 TaxID=2203210 RepID=A0A3Q8URG6_9ACTN +hrTARSRIRRAFAEAGVTGQLHARDIDTGAEL-AVAADTPVSTASVHKVCLLATLYREAE +HGRVDLTAAVEVPAGGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI +EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLTAVWRDEVCTGAYAA +DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAGRLAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus hammesii DSM 16381 TaxID=1423753 RepID=A0A0R1UQM2_9LACO +--AVESDITTAFKSLDGTNSAYVSPVNGQQQV--VVNNGAQSSASSIKVFILVTAYAMAK +EGVFNLNATHTLTASEKVGGTGVIQNMSDGTLTYREILKHMIDDSDNTGANIMIAKMGGF +GLINNKIKNMGATDTKLQRKMMDTD-AIDQGRDNLTSARDLGMTLKKLYNHQLVSKSADD +EMLAILADNQN-RTKLPKLLPSSAKVYNKTGEYDYGVQNDAEIVANRHGA-FVAVVLSQD +GHEA--DQVAA------------ +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora costi TaxID=1530042 RepID=A0A3B0AEG0_9ACTN +---VEERIGTIFGRAGVSANLHVVDLDDGREV-AVRADEQVVIASIFKILLVLEFARQVA +AGQLDPTERVLVTAADRLGGWGLAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLTRTRVVGGPRQLVEVFDPEQTTSSTAREITRLLGLVWRDEAGPPEACA +LVRGWMARQLF-WTRLAAGFPAGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFART +EQLDTRRVDLAMGEAARTAV--- +>[subseq from] hypothetical protein n=1 Tax=Heliobacillus mobilis TaxID=28064 RepID=UPI0012D73891 +---LKQRIKKEMADFSGSFAVYLEDLSTGHQF-GINSNMAFPAASVIKVPLVLFLYSLAL +DGRINLDETISIVPSDLEPPGGLWSYNIGTTYTLRQLAKHTIEDSDNTAANMLMRRL-GR +TNFYLFLRLSGASVIPW---GP--------GKGNVTCARDAALYLKGIWLFRQIEHPLGE +EMMQYLLHSKF-DDRIPAGVPFDVEVANKIGSQE-GVFNDTAIIFLPNR-PYVLSVLCCH +PD--EQQAVEAIGRIARLTYEY- +>[subseq from] Serine hydrolase n=2 Tax=Nonomuraea sp. KC310 TaxID=1848322 RepID=A0A4R4V474_9ACTN +------QAREALAAAGATGTFHARHVGGGAEL-ALDADAVQVAASTYKVAVLLEVACQAV +AGELSLTRRVRVPGDVRSPPSGISSMLDEVELSVRDLALLMMQVSDNTATDVLQEIV-GT +ARIAARLDALGIRDTTVRLDCAGLIAALAGTTGNTTTARDMTTLLSLIWRDEAGPPEACE +EVRRVMLQQYA-PHRLSTAYRDGPKIAGKTGTFYGGVRNEVGVVDFGDGEEYAVAIFLRQ +HELRDGRADAAIGAVARLLVDH- +>[subseq from] serine hydrolase n=1 Tax=Nocardia lijiangensis TaxID=299618 RepID=UPI00083599A4 +----EERIREIFAELPVRGRLHAVDLADGREL-GVGADDQVVIASIFKILLILEFSRQVD +AGQLDPTERVLVRAADRLGGWGTAGCADDVEMSLRDLAYFMMSVSDNTAADLLLRRI-GP +DTPALLAAELGLASTRVIGGPRQLLEVFRPEHTTSSTAREITRLLGMIWRDEAGSPAACA +ATRDLLRRQMF-WTRLAAGFPDEVLVASKTGTLP-GLHMEAGVVEYPDGGRYAVAVFAHS +DETRRIDVDLAMARSARLAV--- +>[subseq from] serine hydrolase n=1 Tax=Acetobacter senegalensis TaxID=446692 RepID=UPI00128D6033 +---LAQSISKSVKAQPGHFAVYAALSGRSPAV-CLNCDDLINAASTIKLFVLDAAYDAFT +KGTLHPQDTITVHNRSLVGTGTFAYAQAGKPVPVSELLRVMIQYSSNLATNLMVEKL-GV +LPIRSVVKAQGLDGIVFGRMIEDFDAN-DKGIRNQVSARGLGAFLQKLDNGQIVGKAQSQ +SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGKHYILVVLTSD +LP-DEQAGIKVLNTLSHQTYTYf +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6JFB7_9BACT +-kKLQARVDEIAERFDGVTGVAIVDLTDDRAI-LKNTDHVFPTASSIKIAILLELYRQEQ +AGKAKLDDSYTFDAKDLVDGSQIMTGLTPRVLTNRDLAQFVVAVSDNAAANVLIDRV-AM +QNVNATLRNLGLTKTMLRRKMMDIAAAKRG-DENVSTPQEMTRLLQAIYQGKALDKELAE +AFMKQLSTKKE--SYIPRRLPPDVPVAN-------------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. or43 TaxID=2478957 RepID=A0A652LSQ5_9ACTN +--------------AGVRGWLHVAELHRSAGV-TIDPDVRLPMGSVYKVPLMVAFCRLAD +ADLIDPRRRLTLDPADRVPPTGVSLLRDPVTMSLRDLVAQMMSISDNAAAAAVLREV-GA +DAVDAMCQELGMPGTHIHGGVVSTFSVYDPAYKASSTASDMARLLRAIWTGQAASEDSCA +FMREVMRSQPW-THRLASGFPDDVTVYGKTGTFG-ALRHEAGVVELADGSAYTAVVFTQA +ARADLPRADAVIGAAARAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Achromobacter dolens TaxID=1287738 RepID=UPI000A42E3E3 +-qHVDAALAPLLAATPARVSLSLRDLDGGIVL-AHHADRVQPSASIIKVPILLALLEAVA +KGRYALEQPLALPATERAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIELL-GF +DEINQWNQRAGLPASRLQRRMMDAAA-REAGRDNFTSAEDATASLCWMLRDGALPAALRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FT--------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNQ-509 TaxID=444103 RepID=UPI00099CB6FB +hrTARSRIRRVFAEAGVTGQLHARDIDTGAEL-AVAADTPVSTASVHKVCLLATLYREAE +HGRVDLTAAVDVPAGGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI +EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLTAVWRDEVCTGAYAA +DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAGRLAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. H219 TaxID=2492662 RepID=A0A426K0R6_9PSEU +-------------EFPGRVGIASWDLDEGVPV-LRCPEVEVHSASTIKVLVMITALRAVA +EGRLDLDRVVPLPAS-RTRGTGVLFEIPSVPMSLRDLINLMIVVSDNAATNAVIDEV-GF +PAIAACTAGLGCTGTRVERHIMDTA--APGV--LQTTALDQARVMAALARGEALPPEQTR +HALAVLSRQQV-VDRIPLRLPEDARCWNKTGEIK-GLRHDVALLSADDTPRVVLAVLVDQ +LTDP------------------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. TM32 TaxID=1652669 RepID=A0A4Q1RW54_9ACTN +---TQDHIRTAFADAAVTGWLHACDIDTGAEV-GLHPDHPVVTASVHKLCLLVALHQRAA +QGDFDLTDQIEVPPTGRTFGRTGLGAMLDPAMSLRDAAYLMMSVSDNIAADLLLERV-GL +DAVNRTTTQLGLAHTLAVHTFRQLLDALDPARTNRSTPRDMTRLLSCIWRDEAGTPDHGA +AIRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA +ANATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Pedosphaera sp. TaxID=2024890 RepID=A0A2D8UVD1_9BACT +-hDLEQTLRIAIESFQGEVGVYVRKLDGGCEV-AIGADELYPTASLIKVPIVMALLDKVE +VGQLDWNRPIXYRTSQRSTGEDLMAKFKDGSISLDKLIFLTQSVSDNTAARLAQDLAGGG +AAINRWLASNQWLHTRVNARVDGRSPFYDQYGWGQTTPREMAEMFIALRQRRAISPHADE +YLDRMLGKAYW-DDEALSAIPSDVHVISKQGAIN-ASRSEVLLVSAPSG-PYVLCVITRN +QTGDDNEGFQLLRQLSRLVWN-- +>[subseq from] Serine hydrolase n=2 Tax=Actinobacteria TaxID=1760 RepID=A0A329QFI7_9ACTN +----ADRIQRCFDDAGILGSVHAIALHDHGEI-GVLSDEPAVLASVYKLPLAVAYARMVD +AGRLDPRATVMLDPETRTHGATGFAAMTDPVVTWRDAVRSMMAVSDNAAADALLDVV-GI +TRLADVLDDLGLASTRITGGIRDLYAFDPANPHNSITCRDMTRLLSSLWTDRAASPEQCE +FLRTIMAQQVW-TQRISAGFPDDVIVAGKTGTFV-GLRHEAGVVEYPNGEAYAVAVFTTS +TRARLPAAETAIAQAAKLAVAH- +>[subseq from] Uncharacterized protein n=1 Tax=Solitalea canadensis (strain ATCC 29591 / DSM 3403 / NBRC 15130 / NCIMB 12057 / USAM 9D) TaxID=929556 RepID=H8KVC5_SOLCM +-kKLNGELQELVKGFNGTVGIYVKNLKTGKTA-AFNADTIFPTASMIKVPITIGLFNKIN +KGELKYDSVLTYKDSLLYEGEDILGSFKNNEVALSKVAMLMITTSDNTASLWCQSMAGKG +TTINEWLGTNGFQYTRVNSRTPGREANRKLYGWGQTTPLEMAELLVRIRRNEVISPAISE +RIYRNLIRIYF-DGEALSQIPPYIQVASKQGAVDQ-SRSEVVLVNAPHGD-YVFCIITKN +QKDENNEGYVLIRKLSALLWNYf +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis thermoflava TaxID=84480 RepID=UPI000419DDD8 +-------------AAGVRGWLHARCLDCDGET-GHHPDEPVVLASVVKVPLVLELARQVA +AGQLDPADRLRVTAADRLGGTGTAGCADDVEMSLRDAAFFALSVSDNTAADLLFDRV-GL +DNVRSLLRELGLADTRVIGSPRDVVAALDPLRTSASTPRDMTTLLAAIAGDTAGPPEACH +WVRQLMGQQVN-WHRLTAAFPPQVRVWGKTGSLL-AVRNEIGVAEYPGGQRYAVAVFTKA +PTSRLPDVDHAIGEAAKAAIE-- +>[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora sp. HAJB-30 TaxID=2715536 RepID=UPI00140B3CB2 +----TTRLENTFADAGVTGYLHAVDIDSGAEV-GLAPDTPVVTASVFKIYILLELCCRSA +EGSLGLTDRIRIPAGDRSLGPTGLSVMLDDTLSLRDAAYLMMSVSDNHATDVLMDFL-GV +QAINDRLRTLGLEQTVAMYSCDALFRALDPEQTDRSTPRETTALLTELWRPRTLPEEACA +EARRIMGLQVW-PHRLTSGFPDDITVSGKTGTLSH-VRNEVGVVEYPDGGRYAVAVYLRL +PGRENPVADAVIGRAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Terrisporobacter glycolicus TaxID=36841 RepID=A0A354KMV4_9FIRM +------------KSIDGDVSFYYKNLTTNNTV-AYNEEKIMLAASVIKLTVLVEAFKQIK +EGKIKKEEIFITCEDDKVPSCGALNYMREGLVTLEDLYVLMIILSDNYATNMLIDKL-GM +DNINNTIKEIGLRNTVLNRKMFDSKKS-ALGLENYISASDVGYLLEKMYNKDLIDEKSSE +EMINILKNQRL-NGKIPHNLKPKIDIAHKTGEDTN-TTHDVGIVFAK--EPFIICFCGNN +VN--VPEYERLIQDITYDLY--- +>[subseq from] serine hydrolase n=1 Tax=Cupriavidus malaysiensis TaxID=367825 RepID=UPI000A6EFD4A +--RVEAGLAPLLAATPARVALSLR-LRDGSIVlERAASCAMPSASLVKVPILLAMLEQVG +QDRLRLAQEMSLAGIERVGGTGILAQLPSVRLTLAELARLMIVLSDNVATNALIALL-GF +DAVNGWCERAGLAQTRLQRRMMDAAAR-AAGRDNFTSAGDTAAALGWLLRGDTLPAPLRA +FGLALLADQRE-RAHFGAALPAAARLANKTGQLP-GLRHDAGILTVGDQ-SVVLAVLADG +FTDPRTARE-------------- +>[subseq from] serine hydrolase n=2 Tax=Veillonella sp. CHU110 TaxID=2490947 RepID=UPI000F8F278F +--KARQKLSQISDSIQLAPYESVYIGYHGESV--VKQSKPMRAASMIKVYILGYLFEEVE +AGRISLDETILLQRSDQVGGAGILSGYSGTALTIDELAKLMITISDNTATNILIHRL-GI +ENINTYIVKHRYADTKLQRNMMDLT-AIEEGRENYTSAKDLGTWFMNLLDGKNMSGASRE +KMLTYLLGQTD-TETFNEALP-NRSIAHKTGELG-GVYHDGGIIFQNN------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Pseudopedobacter saltans TaxID=151895 RepID=A0A2W5ETQ7_9SPHI +-tKLEKKLKPLLDSFHGVSAIYVENIKTGKIV-AINADTIFPTASIVKVPILTAVYSQIN +AGKLQYNQPLIYKDSLKYGGSGLMQFFKDSSTDLSTAAALMIDYSDNTTSLWLQLLVGGS +DKVNDVMESIGLHNTRDNRTNREAFRSIYG--WGQTTPREMATLLKLIFQKKILTPSSCE +SMYRTMSHVYY-DNFSLSQIPPYVQTASKQGMVDD-SRSELVLVNAPHGD-YVFYIATKK +NKDQDNEAWELQRKISSILWNYf +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces indicus TaxID=417292 RepID=A0A1G9GJM8_9ACTN +---------------------------DAAEV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAHDRLGGWGTAGCADDIEVSLRDLAYFALSVSDNTAADLLLARV-GP +DTVQLLAKELGLDRTRIVGGPREALAVLDPQRTNSATPREITRLLRLVWRDEAGPAQACA +LVRQLMSRQVF-RHRMVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGGSYAVSVFART +REAARTAVDSAIGATARIAVD-- +>[subseq from] Beta-lactamase class A n=2 Tax=Saccharopolyspora TaxID=1835 RepID=A0A1H6EMA2_SACHI +---VERRIREVLADAGAEGWVHATQFGGGREI-CLGADELVVTASVYKLPLLVAMCRAFD +AGRLDPRATVRIDPTSCTPPSGFSTFLDPVTVSWRDLAASMIAVSDNSAADVILGAV-GL +DAVADVLADLGLTRTRVVGGTADQHAAYDPAYASATTPREMTRLLELIWTDAVASPQQCA +FIRRLLGNQIW-LHRVRSGFPQGVRVAGKTGTVG-AVRNEVSVVEFEGEEPVAVAVFTLA +ARADLPRVDTAIGECA------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. GZWMJZ-114 TaxID=2494734 RepID=UPI001013A724 +--AVADRIAAAFADAGVDGVVHAVDIDRGTET-GWEADRLVCTASVHKLCLLLALHRLAA +AGRIDLTERVECPVEGRTPGTGLAAMLDAPRMSLRDLAYLMIAVSDNAAADLLLARV-GL +EEVNRTTEALGLRRTRAVESFAATQEALDPAHGNRSTPRELTRLLAALWRDEFLPEAHGA +AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA +ADHVVPAADAVIGVVGRIAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5RE43_9BACT +------------------------------------------------------------ +----KLDDIYTFDPKDLVEDSQIMAGLTPAVVTNRDLAQFMVAVSDNAATNVLIDRV-GM +QNANATLRSLGLTKTMLRRKMIDIAAARRG-DENVATSQEMTRLLEIIYKGKALNKEVTD +QFIKQLKTLKK-DSYLSYELPADVELADKPGSLD-GIRNDSGIIFAPNR-PFAITVMTAY +DR-DEKAAERAIGQVALEAFHYf +>[subseq from] serine hydrolase n=1 Tax=Cellulophaga sp. BC115SP TaxID=2683263 RepID=UPI001411F924 +-kALEKKLQVLVNNFQGVAGIYVKHLKKNTGV-AIQADTVFPTASMIKVPITIGLFNKIE +KGELDYHAILTYKDSLLYAGEDILGSFKDGEIALSKVAMLMITTSDNTASLWCQAMATG- +TAINEWLAANGFENTRVNSRTAGRESYRKIYGWGQTTPREMAELLVKIRKGEVINPAASE +RIYRNMVRIYW-DGEALSQIPPTIQVASKQGAVNQ-SRSEVFLVNAPSGD-YVVCVTTKN +QKDENNEGYQLLRNVSKIVWEHy +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces tsukubensis TaxID=83656 RepID=A0A5H2US86_9ACTN +-----ARIAAAFTGAGVTGWLHARDIDTGAEV-DAGADRPVVTASVHKLCVLVALHEAAA +AGRLDLTEQTEIPAHGRTPGPTGLGSMLDGALSLRDAAFLMMSVSDNAAADVLLERV-GL +DAVNATTRRLGMPRTEAVETFGSFLGALDPARTNRSTPRDMTTLLAAVWRDEAGAPDHCA +AMRRILGLQVW-PHRLASGFPDDVQVAGKTGSAPT-LRNEVGVVAYPDGGRYAVAVFTRA +ASATLPAADAVIGTAARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces exfoliatus TaxID=1905 RepID=UPI000467EB95 +--ATRRRITAAFADAGVTGQLHAADIDTGTAL-GVGSDTLVPTASVHKLCLVATLYRQAS +LGLVDPTRPVDIPAAGRAPGATGLSAMRDAALSLRDLASLAVAVSDNTAADLLWDAL-GL +DTVNATMTGLGLTRTHAVQTMRELLAALDPTRTNRSTPREITALLAAVWRDEVCPGEYGE +ELRALLGLQAW-SHRLAAGFPDDVRVSGKTGSLPT-LRNEAGVVEYPDGGRYAVAVFTRA +ASTDLPAADAAIGAAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Microlunatus speluncae TaxID=2594267 RepID=UPI00137580A2 +--------------GPATVSVTLLD-DHGDTVaEVNPDAQHYAASTMKLPLVLAAYRLAA +AGKLDLDAELPVHNEFTSQGTPFGWDRLGGTATLRWLCQRSVVRSSNLATNLVLDQV-GL +PAVAEAIATCGATGVSVGRGINDYAARDRLGDRNLITTRGLATILSALHHGTAADRTTCD +AVLAVLAANEV-ATDLRAGLPPGTWVAHKNGWVTD-VVHDAGLIRPPDARPFVLAVATTA +PWP-GEVAHAFIASIAAAVWE-- +>[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522R577_9BACT +-rKLTEKLQKVVDSFHGTAGVYVLNLKTHQEA-AINADTLFPTASIIKVPIIVAIFKKIE +DGQLNYHQPLLYRDSLAHGGSGIMQYFKDSTTNLSVAVTLMISHSDNTAAHWCQTLAGGG +AAINVWLENHGFQYTRDNSQTPGREDADNLYGWGQTTPREMAHLLLLIRENKIITPAACE +RMYRDMTHIFW-DDYALSQIPPYVQTASKQGMVD-ASRSELVMVNAPKGD-YVFYVATKN +NKKPDNEAWQFARNVSALLWHYf +>[subseq from] Serine hydrolase n=1 Tax=Pararcticibacter tournemirensis TaxID=699437 RepID=A0A4Q0M5L9_9SPHI +-kKLTALLQDAAKGFDGTVGIYVQNLKTNKTA-AINADTLFPTASMIKVSILCGVMDKIE +KGELLYNQKLVYRDSLLYPGVDILGSFKDNEIDLSKVAMLMITMSDNTASLWLQKLVSG- +TYINNWLDQNGFKVMRVNSRVEGREPARKIYGWGVTTPYEMCRLFTLIRNGKVVSPAASE +RIYRNLVRIYW-DEGALSQIPPYVQAASKQGAVD-ASRSETVLVNAPHGD-YVFSVITKN +NKAETNQAHQLIRRISSLLWHYf +>[subseq from] serine hydrolase n=1 Tax=Acetobacter indonesiensis TaxID=104101 RepID=UPI000A390ED6 +---LAHQIEKTVQGQKGLFAVYAARVGATPEV-CLNCDHLINAASTIKLFVLDAAYKAFA +SGTLHPTDLIRVHNHSLVGKGTFAYAQQGKEVPVSELLRVMIQYSSNLATNLMIEKL-GV +FPIRDVVKEQALDGIVFGRMIEDFDAD-AQNIRNRVSARGLGEFLQKLDQGQIVGKEASQ +SMIAIMLGQKF-NDIIPPGLPAGTPVAHKTGWVN-GVKNDAAIITLPDGAHYILVVLTSG +LP-DEAAGVKILNVISREVYDYf +>[subseq from] Serine hydrolase n=2 Tax=Streptomyces sp. A1499 TaxID=2563104 RepID=A0A4S3GPW1_9ACTN +--DVQRAIRGMFADAGVRGWLHVAELHREARV-TVDPDEPVPVGSVYKVPLMAAFCRLAD +AGALDPRQPVTLGPDERMPRTGISILRDPITVSLRDLVVLMMSVSDNTSADAVLRHV-GP +AAVVELCRDLGLPDTHILGGAATTFEVYNPLSKASSTPSDMARLLRAIWTDGAASAESCA +FMRETMGQQAW-SHRLASGFPDDVTVSGKTGTFGT-MRHEAGVVELPDGGVYTAVVFTQA +ARADLPRADAVIGTAARAAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis regifaucium TaxID=546365 RepID=A0A154MRL7_9PSEU +------EIEAVFANAGARGFVHAREVGGGPEV-AVGADDPVVLASVFKIPVAVAFAREVA +AGRLDETERTRVTARYRIGGVGTAGCADDVEMSWRDLAHFMLTMSDNAATDLIYHRI-GQ +AAIDQVLTDLDLTRTRLIGCCEDLFAVVDPERTTSSTPREITTLLDAIWTDRAGDPAACE +RVRTIMAQQIW-PHRISSGFPAEVAIAAKTGTLPS-VRNEAGVVTHVDGRRFAVAVFTRA +DSLDLPAVDSAIGEAARLAVEH- +>[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobiales bacterium TaxID=2026801 RepID=A0A3D0XIZ2_9BACT +-hDLEQTLRIAIESFQGEVGVYVRKLDGGCEV-AIGADELYPTASLIKVPIVMALLDKVE +VGQLDWNRPIVYRTSQRSTGEDLMAKFKDGSISLDKLIFLTQSVSDNTAARLAQDLAGGG +AAINRWLASNQWLHTRVNARVDGRSPFYDQYGWGQTTPREMAEMFIALRQRRAISPHADE +YLDRMLGKAYW-DDEALSAIPSDVHVISKQGAIN-ASRSEVLLVSAPSG-PYVLCVITRN +QTGDDNEGFQLLRQLSRLVWN-- +>[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. LD22 TaxID=2650748 RepID=UPI00124EF25B +------------RDAGVTGFLHAADIDTGREV-AVAADAPVVLASVFKVPLLVAFHRLAA +QGRLDPTEQVTLAAGDRTSPTGVSALLDDVRMSLRDLACLMITVSDNAAADALLERV-GL +EAVNAAAEGLGLRATVVTGGGRQLFDALDPSRTSRSTPRDMTRLLAAIWRDEAAPPDGCA +AMRRLFGLQVW-PHRLSSGFPDDVLVSGKTGTLLT-VRNEVGVVEYPDGGRYAVAVFTRS +LLAVLPQADAVIGTAARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces olivoreticuli TaxID=68246 RepID=UPI000E24A231 +----LARIRDAFDAAGVTGRLHALDIDSGAEI-NAGADLPVVTASVHKLCLLVALHQRAA +AGHVDLTEQIECPPAGRTLGPTGLAAMLDPVMSLRDAAYLMMAVSDNTSADILLERV-GL +DAVNDTTARLGLTHTHAVHTFGRILAALDPARTNRSTPRDMTRLLAAVWRDEACAPEHCA +AVRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA +ASATLPPADAVIGTTARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Cupriavidus sp. USMAA2-4 TaxID=876364 RepID=A0A1D9HBH7_9BURK +--RVEAGLAPLLAATPARVALSLR-LRDGSIVlERAASCAMPSASLVKVPILLAMLEQVG +QDRLRLAQEMSLAGIERVGGTGILAQLPSVRLTLAELARLMIVLSDNVATNALIALL-GF +DAVNGWCERAGLAQTRLQRRMMDAAAR-AAGSDNFTSAGDTAAALGWLLRGDTLPAPLRA +FGLALLADQRE-RAHFGAALPAAARLANKTGQLP-GLRHDAGILTVGDQ-SVVLAVLADG +FTDPRTARE-------------- +>[subseq from] Serine hydrolase n=1 Tax=Kribbella sp. YM53 TaxID=1572659 RepID=A0A4R0JZE9_9ACTN +-----ARIRAVFEDAGVRGWLHAVALDAPEATvDVDADTVVPMASVYKVPLLAGFCRLVD +LGEVDPRRQLTLDPSTRTAPTGVSILADPVTMSLRDLAVSMITVSDNASADALLDVV-GL +QRLAELLESFGLKRTWVRRGTAGNLRVYEAANASASSPRDLTTLLRRLWTGELLSEQQTA +FVRATMHRQLF-MHRLASGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGAAFAIAVFTLA +ARGDQPRVDAAIGEAARVAVD-- +>[subseq from] Uncharacterized protein n=2 Tax=root TaxID=1 RepID=A0A2E7QRB3_9CHLR +-eQLNERIGEMIYTFPGIAGCCVKSMTDGNII-SVNGDVEFPIASTIKIPILLQLLVLDE +KGELDINELIDITPEMIYPGSGIISYLEGPVLSILDIAILMIIVSDNTSTNLCIDYA-GI +DKTNDMLRSLGVDNITLRRKMQDTESV-VANRENVGTPDDCVLLLEHLYNGRP-TQNSAD +RCLSILRKPKR--SILNRFIPTETPLANKPGGMAR-VRCDAGIVYLSQY-PYAVSIQTSF +SEIEPEDQENFIVELGSMI---- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. TverLS-915 TaxID=1839763 RepID=A0A1C4KZ71_9ACTN +--AVADRIAAAFADAGVDGVVHAVDIDRGTET-GWEADRLVCTASVHKLCLLLALHRLAA +AGRIDLTERVECPVEGRTPGTGLAAMLDAPRMSLRDLAYLMIAVSDNAAADLLLARV-GL +EEVNRTTEALGLRRTRAVESFAATQEALDPAHGNRSTPRELTRLLAALWRDEFLPAAHGA +AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA +ADHVVPAADAVIGVVGRIAVD-- +>[subseq from] Secreted beta-lactamase n=1 Tax=Streptomyces sp. (strain SPB78) TaxID=591157 RepID=D9UTF0_STRS3 +--AVADRIAAAFADAGVDGVVHAVDIDRGTET-GWEADRLVCTASVHKLCLLLALHRLAA +AGRIDLTERVECPVEGRTPGTGLAAMLDAPRMSLRDLAYLMIAVSDNAAADLLLARV-GL +EEVNRTTEALGLRRTRAVESFAATQEALDPAHGNRSTPRELTRLLAALWRDEFLPAAHGA +AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA +ADHVVPAADAVIGVVGRIAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A4P5WFL1_9BACT +--------DAELVRFPGKAGVWVKHLTTGEEA-GVHAHDTFNTASVIKIPVLVLAMQLAD +QGSLSLSERITIGASEMRGGSGIFRYDPGLQPTFRDVLTQMIITSDNTATDIAIGKTGGV +DAVNRWLVASGYGGTKLSMTTADLFATDRSYWLGEMTPHATGRMLEAIQRCHVASKAACA +DMMRMMRGQQSGARRLPHFLN--VPVAHKTGDFPPALANDVGVIFTRSG-PVVVAFFANA +IEGPYADAEDRIGQIAQRIVDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CNZ289 TaxID=2572907 RepID=A0A559UVY7_9ACTN +hrTARSRIRRAFTEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE +HGRIDLTAAVDVPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI +EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA +DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAARVAVD-- +>[subseq from] Uncharacterized protein n=2 Tax=Candidatus Shapirobacteria TaxID=1752721 RepID=A0A2M6YQK0_9BACT +--SVLDQIQSLTKDLRGKYGVYVYELDDKNQY-GVYQNEKFPAASLMKLPVMLLFYQELE +EGKIDPEAKYTLKENDKVLGAGILQKSVGTVYTYRQLVEYLGQYSDNTAFKVMRQIL-GD +EKIQQTIDDLGMTKTSLEDFE--------------TSPTDIGLFFQKLYQGKIITTENRL +ELLDFLTKTAY-EDWLPAGMSKKIKVAHKIGRDT-GTFSDAGIVFAD--KPYIIVIMSKK +ARE--IEANEVLPKISSLVWD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0012B90BED +---------------RSNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID +EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIMVSDNTATNEIISLV-GF +EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE +KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-MYYAVVLIDG +LS-DNEQGRRLITDIGYL----- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. S4.7 TaxID=2705439 RepID=A0A6C0Q333_9ACTN +--------------LGARLWLHARCVDCGRAA-GHAEDEPVVLASVVKVLLVLEFFRQVV +AGQLDPAERAVVRAADRLGGTGTAGFHDDVELSLRDLALMTMSVSDNTAADILFRRV-GL +DTVQALARQLGLERARVTGAPREVLEALDPARTTSATPREMTRLLSLVWNDRAGAAAACA +GVRELMSGQVN-GARLGAAFDRFTTVAAKSGTLP-GIRNEIGVVTYPDGARYAVAVFTRT +ASTRRPDLDAAIGGAGREAV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02460 TaxID=1703941 RepID=A0A1Q5K1L9_9ACTN +------ALSSTFTQAKVEGTVHVRDLDTGAEF-AHAADTPVVLASVFKIPIALEYARQAA +SGELDPARRHSVTSAYRAGGSGTDGCAHDVEMSARDLAFMMMTISDNAATDLLLDIV-GP +DRVRATLDGLGLPGFGFSSCS-ALDDACTPGTSPSSTPREVTALLAAIWHDEAGPARACA +EVREIMRAQVW-QHRLVSGFPPGVRLAGKTGTDFS-VRNEAGVIEYPDGKRYAVGVFLRT +STTRQPLADRAIGRAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora hirsuta TaxID=1837 RepID=A0A5M7BE95_SACHI +---VERRIREVLADAGAEGWVHATQFGGGREI-CAGADELVVTASVYKLPLLVALCRAFD +AGRLDPRAAVRIDPTSCTPPSGFSTFLDPVTVSWRDLAASMMAVSDNSAADVILGAV-GL +DAVAEVLDDLGLSRTRIVGGTADQHAAYDPAYASATTPREMTRLLELIWTDAVASPQQCA +FIRRLMGNQIW-MHRVRSGFPQGVQVAGKTGTVG-AVRNEVSVVQFEGEEPVAVAVFTLA +ARADSA----------------- +>[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. NEAU-AAG5 TaxID=2678616 RepID=UPI0012E295B5 +---------------------HAADIDTGREV-GLRADAPVVLASVFKVPLLVAFYRQVA +DGVLDPTEQLTLRPQDRTAGPTGLSALLDEVVSLRDLACLMIAVSDNASADVLLERV-GL +DAVNAAAADLGLRRTRVEGSGRDLFEALDPVLTSRSTPREMTRLLGAVWRDEAAPAAECA +AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-IRNEVGVVEYPDGGRYAVAVFTRS +LLAVLPQADAVIGTSARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Gordonia sp. HS-NH1 TaxID=1435068 RepID=UPI0006E31274 +--------RETFTDAGCSGCVHARTIGTPVEF-SHDADAPVVLASVYKLAVLISLCRLAD +RGDIDLAASITVEPTRWAPGPTGLALFTDPVMTWRDLATSMMTVSDNVAADVILTHI-GL +PRIHADLNQLGLAHTRIVGGVAELHEAYDAAYSSSATPRDCTTLLDAIWTDRAASAASCE +FIRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AVRNEVGVIEFPGELPVAVAVFTMS +ARSELPEVDRAIGEVARAVVT-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. MKU004 TaxID=1849370 RepID=UPI0009EDFC4C +---LERQIHELVEGVEGRISLNIEL--PAHTI-QLHSDVPYSAASLIKLPILLEGFRQIQ +ERKLDPEEVIPVTQEDKVGGAGVLSHLSPHTVTVHELLTLMIIVSDNTASNLLIDRM-GM +DSINGMCRLLGLEQTKLNRRLMDFE-ALESGVDNHISATDAVKCLKGMENEVLFQLSSRE +SMIRILENQQF-YQKLPGSMDNRVFTANKTGELP-GVEHDCAIIRYNQK-TVYAAVLIDE +LK-DSSEGSGLIMKVGKCLND-- +>[subseq from] Serine hydrolase n=1 Tax=Kitasatospora sp. MMS16-CNU292 TaxID=2567942 RepID=A0A540WGM1_9ACTN +---ARARIAEAFAEAGVTGLLHARDLDTGTEL-AHGADTLVSTASVHKLCVLTTLFRQAA +AGRIDLTRRLDIPAFGRTDPTGLAAMLDAARLSLRDLAYLSIAVSDNTAADLLWDEL-GL +DAVNGTMADLGLTRTVAVHKIRDMIAVLDPAFTNRSTAREMTALLAAIWYDQACPGEHGA +ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVIEYPDGGRYAVAVFTRA +TATSLPAADAVIGTAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis taiwanensis TaxID=342230 RepID=UPI00048936BF +----EREITARADELGLRVRMHATDIDGTASF-GISSAEPVVTASVFKVPVAVELARQAV +AGECDLAEQVTVPAGPKVPYGLATFRH-PATLSLDALATLMIGISDNVATDLVFARV-GK +PAVRSLLDRLGLTATVIDQDCAELLAALQPDQTCRTTPEDMTRLLGMIWRDEAAPPQACA +EVRRWLGLQVW-PHRLRSGFHDDVRISGKTGTLPT-IRNEVGVVEYDDGGRFAVAVFTEA +VDAQAPERDAFIGFAAARAI--- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. YIM 10 TaxID=2653857 RepID=UPI00129079FE +------------EAAGVRGWLHARRLDTGAEC-GWGADEPVVLASVVKVPLVLEFARQVA +AGQLDPRDRVRIGARDRLGGSGTAGCADDVELSLRDAAYFAMTVSDNTAADVLCDRV-GL +DNVRSLVRELGLARTRIAGAPRDIVAALDPGWTNASTPREMTALLGHLWTDQG---EPAA +QVRQWMGQQVF-WSRLGGAFPPEARVWGKTGTLPC-IRNEIGVVEYPDGARFAVAVFTRS +ALQRQPAVEQAIGAAAAAAV--- +>[subseq from] Serine hydrolase n=2 Tax=Candidatus Cryosericum hinesii TaxID=2290915 RepID=A0A398DSJ9_9BACT +-qDWQEQVRVLLDGAQGKFGVYAA-TPTVPLF-EYQASSIFPSASTIKVLIMAELLRQVE +AGTHALTEHP-VLPTAPTGGCGILEFLSSDYPDLMDLLHFMICSSDNKATNVLIHLT-GI +DAVNQLAVDIGMTNTRLRRFMMDTES-IQQDIDNTTSPADMGRFFKLLACNELVSSKASA +TMKTILGHQQF-ADIMMLFLPEGIRAEHKTGGLP-GSVLDVGLVYGA-RDPLILCLMATQ +LAN-NGEGAIILGKVAAIAYT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis saalfeldensis TaxID=394193 RepID=A0A1H8XGH4_9PSEU +-----EEIEAVFAGAGAQGFVHAREVGDGPEV-GVGADAPVVLASVFKIPVALAYAREVV +AGRLDETERTRVTARYRIGGIGTAGSADDVEMTWRDLARFMLTMSDNAATDVVFHRV-GQ +AAVDRVLSDLGLSRTRLIGCCEDLFAALDPERTTSSTPREITTLLDAVWTDRAGEPAACE +KVRAIMAQQIW-PHRISSGFPSGVTIAAKTGTLP-AIRNEAGVVTYADGRRFAVAVFTRA +ASDRLPAVDRSIGEAARLAVG-- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0003321813 +-qHVDAALAPLLAATPARVSLSLRDLDGGTVL-AHHADRVQPSASIIKVPILLALLEAMA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNAATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPSPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Beta-lactamase class A n=1 Tax=Catalinimonas alkaloidigena TaxID=1075417 RepID=A0A1G9BA37_9BACT +-kKLQAQLEQLVAGFRGDVGIYVRHLKTGRTA-MIHADSLFPTASMIKIPITIALFDKIN +RGELDYHTPLVYRDSLLYPGEDILGSFQDSAIELSKVAMLMITTSDNTASLWAQSLAGTG +TVINQWLADHGFRHTRVNSRTPGREPNRTHYGWGQTTPREMAELLVMIREGRVINPAASE +RIYRNLCHIYW-DHEALSQIPPTVQAASKQGAVDE-SRSEVVLVNAPSGD-YVFCVITNH +QQQQDNEGYVLLRDVSCLLWQYf +>[subseq from] Uncharacterized protein n=1 Tax=Virgibacillus phasianinus TaxID=2017483 RepID=A0A220U1Q5_9BACI +----EATIHELLKDIIDHFSIYIQT--SDGDI-SINAFEPKRAASTIKLPILIEAFRQIE +AGNLQPDTLVYIETDMKTGGAGVIDYLTNSNYSYRNLLELMIIVSDNTAANIILDKI-GM +DTVNELAAAIGCNHTILSRKFMQLKDP---SLENYTSAQDMVKFLHLMEEDDLLSETSRN +EIKQIMGHQQN-NCKIAHYMNHDIKVYHKTGELT-GIEHDVALLTYQEQK-VYLALLSEN +WQN-NGTGRDYLAAIGKIVLQY- +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter rubeus TaxID=2027860 RepID=A0A5C1I876_9SPHI +--KLTAKLNDAVKDFHGQVGIYVHNLKTGKTA-EINADTLFPTASMIKVSIQCGVMDKIE +KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GS +EYINNWLDQNGFKVMRVNSRAPGREAMRKIYGWGVSTPREMCRLFTLIREGKAVSPAASE +RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHDD-YVFSIITNH +NKTPNNEAGLLIKKVSALLWHYf +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter malorum TaxID=178901 RepID=A0A177G240_9PROT +---LAQIMAETVKNQPGHFAVYAARSGQPPDV-CLNCDDLINAASTIKLFVLDAAYDAFT +KGTLHPEDTLTVHNHSLVGGSFALYAQAGKAVPVSELLRVMIQYSSNLATNLMIEKL-GV +LPIRAIVKAQGLNGVVFGRMIEDFDAN-DQGIRNRVSARGLGTFLQKLDNGKIVGKTQSQ +SMIQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVQ-GVRNDAALVTLPDGKRYILVVLTSG +LP-DEQAGIRVLNTLSHQAYAYf +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI001231E3E6 +-qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAVA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] hypothetical protein n=1 Tax=Bacteroidales TaxID=171549 RepID=UPI0012AF0272 +-------------------------IKDGQFY-GIHENNYFPMNSVMKFPQALFVADWMQ +RNNIRLSDSVKVTKEELIEWSPKLGDIQTSKFTYAELLSYSLMLSDNNACDVLFKRCGDP +KTVEAYIRKLGFKRIHIRKTERQMREDHSCCRYNKATPKDMTLLLQWFSSHNS-DTPILQ +FIWETMMKCETGMDRLPAANPEGAALLHKTGSGYTTDIGDAGIYLLSDGSKWPICVFVKG +ASTN------------------- +>[subseq from] Serine hydrolase n=1 Tax=Jiangella anatolica TaxID=2670374 RepID=A0A2W2CJQ2_9ACTN +---VEGELREAFAAAGVTGFLHAVDVSSGADL-GVDADAPVVTASVFKIPVLVELCRQVA +AGERSPSDRVRIPAGSRTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDTLMALL-GR +ERINAGMAALGLPGTVLEEDCAGLFAVLDPLTTNRSTPRETTTLLRRVWTADGLAPAACD +EIRRIMALQVW-PHRLTSGFPDDVRVSGKTGTLSH-VRNEVGVVEYSDGGAYAVAVFLRL +PGSENPEADAVIGTAARIAVEH- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. jys28 TaxID=2571125 RepID=A0A4U0P4G1_9ACTN +----PARIHAAFAEAGVTGWLHALDIDSGAQI-DAGADQPACTASVHKLCLLVALHELAA +EGGLDLAEQIECPPAGRTAGPTGLAAMLDPVMSLRDAGYLMMAVSDNAAADLLLRRV-GL +DAVNHAMNRLGLTRTHAVHTFGELFAALDPARTNRSTPRDMTHLLGAVWRDEACTPEHGA +AIRRVLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVAEYPDGGRYAVAVFTRT +ANATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Halorussus sp. HD8-83 TaxID=1710537 RepID=UPI00109269F4 +--DLADYVDNYARKLDGRLGVFLRGPDDFEVVyRSRAAETFSSASVIKLPVLYALYEKYD +GRLGGLDRPREIAPENRVAGSGLFHLLSETRPSLQDLARAMIAISDNAATNELIDEV-GI +ERIEQSARDLGMADTRLRRKLMATLGWPEGEPANATTPADCARFFADVLHEATLSSAAYD +RLVVPLEEQKH-ATSFPRYLPFETPIAHKTGSIPT-AALDTGYVSDPDSSPLVFAVFADR +LEH-GRDGSDAIAEIGDAVYA-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. IC4_135 TaxID=2715537 RepID=UPI00141DA505 +-----ASIADVCDDANATVAFHVRSLDGKLEI-GSGADARSVTASTYKVPVMLEVAAQAS +EGRLQLADRIKVPADRRTIPSGISAMTDDVEVSVRDLALLMMQVSDNTATDILQEMV-GT +ENIMSRLRSLGLHSTDITTDCEGIISSLNARGGNTSTPREMTELLSLIWTDKAADAEACA +EVRRVMGLQFA-PHRLSSAYVDGPAISGKTGTFLAGVRNEVGVVDFGDGDVYVVAIFLRD +KNNHMRKVDAAIGKIAALAI--- +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis pretoriensis TaxID=218821 RepID=A0A1H5RFQ3_9PSEU +----------IFEAAGVRGFLHARRLGSSSSV-GVDPDEPVVLASVVKVPLAYEFARQVA +AGLLDPADRVRASAADRLGGSGSAGFADDVSYSLRDAALLALSVSDNTAADLLFDRV-GV +ANVRSLLSELGLTRTSVIGAPRDLLRALDPLRTSATTPREMTSLLAAMWRD----PGPGA +QVLAWMSAQVS-WHRLTAGFPPEVAVAAKTGTMP-GIRNEIGVVTYPDGGAYAVAVFTAG +GAETRPDIDRAIGDAARAAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536D394_9CHLR +--TLASRLDHALLGVDGQIGVAVKDLGSGRGA-VLNGDLELPAASLYKLPVLYAVFDA-- +--GLRMAEELPITDDALSYDAGTMELGAGEALSVAEALERMITISDNTSAVMLGGRV-GP +SRVNSSIAALGMSTTHYSLTR------------MTTSSLDILHLLDLLARGRAVSPAASA +DMLHLLLRQRV-NDRLPRLLPDAIRVAHKTGNLP-GTVNDVGIVYGPSA-TLAIAVLVSD +TT-DEAAAATGIARVAQAAFAYf +>[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma oryzae TaxID=1469603 RepID=A0A2T0TB94_9BACT +--RLAKSLQQLIGSFHGQAGIYVRNLRTGQTV-AINADTLFPTASTVKIPIQCGLFDKIH +QGELSYEQPLTYRDSLHYDDGIVGSLKDGTTIPLSQVVMLMESVSDNTGSLWCQALAGGG +KTINQWLDANGFRQTRVNSRTPGREAFQKQNGWGQTTPRELADLLVYIRDGKAVSPDASD +EMYRNLGRQYW-DHDGLSQLPPSVKAVTKNGAVNQ-ARSEVVLVHAPHGE-YVYCVMTKH +QQDEDNEGTTLMRTVGALLWHHf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2B4Y0_STRVZ +-------LREAFAQAGVTGRLHAVDIDSGVEV-DFGADQPVVTASVHKLCLLVTLHQRAA +AGALDLTEQVECPADLRTPGPTGLSAMLDPVMSLRDIAFLMMAVSDNTAADLLLARV-GL +DAVNLTTAALGLDRTHATHTFGELLAALDPARGNRSTPRDMTRLLAAVWRDEACAPQHGP +ALRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA +ASAILPAADAVIGTASRIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Nonomuraea sp. p1410 TaxID=2603600 RepID=UPI0012F7454B +----------VFAAAGVEGWLHAVDIDSGREC-GYQPDAARPIASVFKVPLLVALCRQAD +QGSLDLGELVRVPVAGRTSPTGLSAMRDEVTISLRDLAYLMIAVSDNASADVLVERV-GL +DTVNAMLAGFGLTGTRVPMSGAQMLDALDPEHTNSGTPRELTRLFAMIWRDEAASPELCA +WMREVFGLQVW-PHRLAAGFPDDVDVSGKTGTLPT-IRNEAGVVEYPDGGRYAVAVFTRS +FSVNQPRADAVIGTAAHMAVDH- +>[subseq from] serine hydrolase n=1 Tax=Eggerthellaceae bacterium zg-887 TaxID=2682777 RepID=UPI00140CF8DF +--DIEASLSQLIEDSGASASFAYRYLSSGWDF-SVHGKEPHTAASMISLAVLTQLFDRID +AGDLSLDDEYELTEEAIVGGNGRLQDDPGTAYSLRDLVWYSIVESDNTATNMLIDIA-GM +DAVNSEVARQGLEGTSLERHMMDTEAQ-KEGRENRMAADDAAAILNAIAQGAFYNEELSD +FAYDLLSQQKS-DSAVKGALPEGATYAFKSGSLEN-VYNEGGVVFG--EHPYVFVAFVEG +VD--EEEATALVKDAAALV---- +>[subseq from] Serine hydrolase (Fragment) n=4 Tax=Streptomyces TaxID=1883 RepID=A0A6B1QJ04_9ACTN +-------LREAFAQVGVTGRLHAVDIDSGVEV-DFGADQPVVTASVHKLCLLVTLHQRAA +AGALDLTEQVECPADLRTPGPTGLSAMLDPVMSLRDIAFLMMAVSDNTAADLLLARV-GL +DAVNLTTAALGLDRTHATHTFGELLAALDPARGNRSTPRDMTRLLAAVWRDEACAPQHGP +ALRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA +ASAILPAADAVIGTASRIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CA-126428 TaxID=2073158 RepID=UPI000CD04E78 +--------------VGVRGFLHAHRLGSAEEV-GLDADSPVVLASVVKVPLAFEFARQVA +AGQLDPTDRVRASAADRLGGTGSAGFADDAGYSLRDAALLALSVSDNTAADLLFDRV-GV +DNVRSLLAELGLTRTTVIGAPRDVLRALDPLRTSATTPREMTTLLAALWADDVGAP---- +-VREWMSAQVS-WHRLTAGFPPEVAVAAKTGTMP-GIRNEIGVATYPDGTAYAVAVFTTG +GAETRPDIDRAIGEAARAAVDQ- +>[subseq from] Serine hydrolase n=1 Tax=Oceanobacillus profundus TaxID=372463 RepID=A0A417YP77_9BACI +-----------------------VVHSTEGTI-QFNANTPRKAASVVKLFILAEVLQQIE +AGRIQREQLISIKPEAMVEGAGVINYLTKHNYSYQNLLELMIIVSDNTASNILLDMI-GI +DRINHSIKKLGCQDTIIKRKFMDQEA-QASGNENITTAADIVHLLKLFSSDNGYSKNLRQ +EVRRLLKNQQF-NNKLAAYQMCKLNIYHKTGELP-GVEHDVAIMESTGRK-LEVAVLTEG +WEN-NGIAQHFIAEVGRYLMNY- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006C4D045 +-qHVDAALAPLLAATPARISLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAVA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus enclensis TaxID=1402860 RepID=A0A1C4BTH9_9BACI +---LERQIHELVEGVEGRISLNIEL--PAHTI-QLHSDVPYSAASLIKLPILLEGFRQIQ +ERKLDPEEVIPVTQEDKVGGAGVLSHLSPHTVTVHDLLTLMIIVSDNTASNLLIDRM-GM +DSINGMCRLLGLEQTKLNRRLMDFE-ALESGVDNHISATDAVKCLKAMENEVLFQLSSRE +SMIRILQNQQF-YQKLPGSIDNRVFTANKTGELP-GVEHDSAIIRYNQK-TVYAAVLIDE +LK-DSSEGSGLIMKVGKCLND-- +>[subseq from] Serine hydrolase n=1 Tax=Nocardiopsis gilva YIM 90087 TaxID=1235441 RepID=A0A223S811_9ACTN +----GERVEDILAEAGVDAQVRVVDIADGREV-AVRADEQVVIASIFKVLLVLEFARQVE +AGQLDPTERVLIGAADRLGGWGTAGCSDDVEMSLRDLAYSAMSVSDNTAADLLMRRV-GL +DIVQILAQELGMRRTRVIGGPRQLLEVLDPAHSTSSTAREVTDLMAMIWRDEAGPARACA +AVREYMHRQIF-WTRLASGFPPEVRVAAKTGTLP-GLHMEAGVAEYPDGGRYAMAVFART +RDTRRIDIDLAMGRAARAAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CMB-StM0423 TaxID=2059884 RepID=A0A2K9EUE8_9ACTN +hrTARSRIRQAFTEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLATLYREAE +HGRVDLTAAVDVPAEGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDTV-GI +EAVNRAMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA +DLRRTLGTQAW-GHRLASGFPDDVRISGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAARLAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. WAC04770 TaxID=2487423 RepID=A0A429UKF0_9ACTN +----------------GWLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD +AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GS +DAVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDEAASPESCA +FMRAAMGTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] Serine hydrolase n=2 Tax=Verrucomicrobiales TaxID=48461 RepID=A0A353DY23_9BACT +-hDLEQTLRIAIESFQGEVGVYVRKLDGGCEV-AIGADELYPTASLIKVPIVMALLDKVE +VGQLDWNRPILYRTSQRSTGEDLMAKFKDGSISLDKLIFLTQSVSDNTAARLAQDLAGGG +AAINRWLASNQWLHTRVNARVDGRSPFYDQYGWGQTTPREMAEMFIALRQRRAISPHADE +YLDRMLGKAYW-DDEALSAIPSDVHVISKQGAIN-ASRSEVLLVSAPSG-PYVLCVITRN +QTGDDNEGFQLLRQLSRLVWN-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. DK17 TaxID=186196 RepID=UPI0002EE34A7 +------------------------------DI-AVGADDLVVLASVYKLPLLVALCRAFE +SGELSPTASVRVNPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL +ASVERTLSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTLLLDAIWTGRAVPGPQGE +FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA +ARTDLPVVDAAIGHAARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter sp. OK098 TaxID=1855297 RepID=A0A1M7NZY5_9SPHI +--KLTAKLQDAVKGFNGRVGIYVHNLKTDKIA-AINADTLFPTASMIKVSIQCGLMDKIE +KGEMQYNQKLVYRDSLLYKGEDILGSFKDGDIEVSKVALLMITMSDNTASVWLQKLV-GG +DYINNWLDKNGFKVMRVNSHVPGREAIRAKYGWGVTTPYEMCRLFTLIRDGKAVSPGASE +RMYRNMGRIFW-DDKAISQIPPYIQTASKQGALDE-SKSETIMVNAPHGD-YVFSIITSN +NKKPDNEAYLLIKKVSALLWHYf +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura syzygii TaxID=1427538 RepID=A0A5D0U6F6_9ACTN +--DITERIEGEFKAAGVTGWLHAVDVDTGREV-SVGADGPVVLASVFKVPLLVAFHRQAA +SGRLDPSEQVVLRAEDRTAPTGVSGMLDDVRMSLRDLTFLMITVSDNAAADLVLDRV-GR +DAVNATSAALDLPNTVVEDSGRELHEVLDPLRTSRSTPREMTRLLSLIWRDEAAPAEGCA +AMRRLFGLQVW-PHRLSSGFPDDVLVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS +LLAVLPQADAVIGTAARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. A23 TaxID=2606593 RepID=UPI001270F313 +-------LSDIFEAAGVRGFLHARSLGSPVSV-DVDADSPVVLASVVKVALAYEFARQVA +AGQLDPTDRVHATAADRLGGSGSAGFADDVSYSLRDAALLALSVSDNTAADLLFDRV-GV +ANVRSLLAELGLTRTSVIGAPRDLLRALDPLRTSASTPREMTALLSALWSD----PGPGA +QVLAWMSAQVS-WHRLTAGFPPEVTVAAKTGTMP-GIRNEIGVVTYPDGTAYAVAVFTVG +GAETRPDIDRAIGDAARAAVDQ- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI00064D95C1 +-qHVDAALAPLLAATPARVSLSLRDLDGGTVL-AHHADRVQPSASIIKVPILLALLEAVA +NGRYALEQPLALPACGGRAGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1H0U0S9_SELRU +--DLQANTARIIGTSKNQMSVYFLRPDREIEP-FLYNQRQMSPASIIKLFVMAKTMQDVH +DGRLSLEDKVTIRKNDVVGGAGVTTWYDGQQRTIRQLLTVMITDSDNTATNILIDKL-GM +KNINQYIAQSGYSDTVLAHKMMLSN----GGRKNLSSVRDLGHLLTKLYYHQLVGPEEDE +FMLSVLKQQHD-KECLGSALN-GYTIAHKTGEVT-GVYTDGGIFIGKDED-FILVIINNG +TEGR------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. BK038 TaxID=2512156 RepID=A0A4V2U1Y9_9ACTN +---TLRRIAAAFAEAGVSGRLHAVDIDSAAEI-DAGADHPVVTASVHKLCLLVALHQHAA +AGLLDLTEQVECPPGERTPGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL +DAVNEATARLGLTRTRAVHTFRSLFAALDPARGNRSTPRDMTRLLTAVWRDEAACTPEHG +AAIRRLLGLQVWPHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA +ASATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CNZ306 TaxID=2035248 RepID=A0A2M9B264_9ACTN +hrTARSRIRRAFTEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE +HGRVDLTAAVDIPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI +EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA +DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAARLAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Pedobacter insulae TaxID=414048 RepID=A0A1I2UBN6_9SPHI +-hKLNKMLTEMVKGFNGDVGIYIKNLKTGKVA-SLNADTIFPTASMIKVPITCGIFNKIE +KGELAYQTELVYKDSLLYAGEDLLGSFKNNEIVLSKVLMLMITTSDNTASLWSQSLAGTG +TVINELMENYGFQHTRVNSRTPGRADNQRKYGWGQTTPREMATLLTLIRDGKMINEAASE +RIYRNLIRIYY-DHEALSEIPPYVQVASKSGAVN-AARSEVALVNAPHGD-YVFCITTKN +QKDTKNEGTTLIRKLSKTLWNYf +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter malorum TaxID=178901 RepID=A0A149RMK5_9PROT +---LAQIMAKTVSNQPGHFAVYAARSGQAPDV-CLNCDDLINAASTMKLFVLDTAYEAFT +KGTLHPEDTIVVHNHSLVGGSFALYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV +LPIRSVVKAQGLNGIVFGRMIEDFDAN-NQGIRNQVSARGLGNFLQKLDSGKIVGKAQSQ +SMIQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVD-GVRNDAAIVTLPDGKRYILVVLTSG +LP-DEQAGIRVLNTLSHQAYEYf +>[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A174D714_9FIRM +--TLEKRIAAELYSYQGKMSVFVDDL-QGHTV-EIGADEKFETASTIKAFILAALYLQVS +RGKASLEEEITYEESQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINGCIRELGFADTVLHNPLH-FD---RYDDLGTTTPRDYAALFAQVAKGTLVSKEASA +EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] serine hydrolase n=1 Tax=Spirosoma rigui TaxID=564064 RepID=UPI0009AF3FBF +--KLEKELRAALTGFRGNVGIYVRNLRTGRTV-AINADTLFPTASTVKIPIQCGLFDKIH +RGELLYDQPLVYKDSLHYDDGIVGSLKDGATISLSKVVMLMETVSDNTGSLWCQALAGGG +ATINQWLETNGFHQTRVNSRTPGRAANQKQYGWGQTTPRELANLLTYIRQGRAVSADASD +EMYRNLGRQFW-DNDGLSQLPPDIKTASKNGAVNQ-ARSEVVLVHAPHGE-YVYCVMTKN +QIDETNEGYTLLRNVSAIIWHHf +>[subseq from] serine hydrolase n=1 Tax=Eggerthellaceae bacterium zg-893 TaxID=2682778 RepID=UPI0013ED9822 +--DIEASLSQLIEDSGASASFAYRYLSSGWDF-SVHGKESHTAASMISLAVLTQLFDRID +AGDLSLDDEYELTEEAIVGGNGRLQDDPGTAYSLRDLVWYSIVESDNTATNMLIDIA-GM +DAVNSEVARQGLEGTSLERHMMDTEAQ-KEGRENRMAADDAAAILNAIAQGAFYNEELSD +FAYDLLSQQKS-DSAVKGALPEGATYAFKSGSLEN-VYNEGGVVFG--EHPYVFVAFVEG +VD--EEEATALVKDAAALV---- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CFMR 7 TaxID=1649184 RepID=UPI0011A52442 +----ERTIRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD +AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GS +DAVDGMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDEAASPESCA +FMRAAMGTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis xylanica TaxID=589385 RepID=A0A1H3H2U9_9PSEU +--TVETQIAQVFADAGAQGFLYAREIGGHAEV-SVGGDDQVVLASVLKIPVGVAYAREVV +AGRLDETARTKVGARYRVGGIGTAGCADDVEMSWRDLALLMLTISDNAATDVVFHRV-GQ +EAVDQVLADLGLGRTRILGCCEDLGKVLDPARTTSSTPREIARLLEAIWTDEAAEPAACE +RVRSIMAKQVW-PHRLSSGFGDEVQVAAKTGTLP-AVRNEAGVVSFPDGRRFAVAVFTRA +ESFRLPAVDASIGKAARLAVDH- +>[subseq from] Uncharacterized protein n=3 Tax=Candidatus Gottesmanbacteria TaxID=1752720 RepID=A0A2M7RS34_9BACT +-eRLKNTIDKALKEAQGTYGIVIRNLNTKEEY-YLNEHREFDTASLYKLWVMATAFTQIQ +SGQLKLSQNIQVLNNKFNIGSESTELTEGTIVSVKEALNKMITISDNYAALLLSEKV-RL +SNVSDFLKKNGLIESRLGEP--------P-----KTTPYDIALFLEKLYKNELANEDNTQ +KMIELLSRQTL-NNKLPKYLPSNLSIAHKTGELGY-FTHDAGIVFTNKD-EYLIVVLSES +DNPS--GAEERIAEISKAVYDYf +>[subseq from] Serine hydrolase n=1 Tax=Emticicia sp. TH156 TaxID=2067454 RepID=A0A2N4X8U5_9BACT +-kKLKAQLQEILNGFNGDAGIYVQNLKTNKYV-AINADTVFPTASMVKIPIMIGTFDKIR +QGSLQYEQELIYRDSLHYDDGIVGSLRDSAKIPLSHVMMLMCTISDNTGSLWLQALAGGG +NRINAILDSLGFVVTRVNSRTPGREAYRSQYGWGQTSPREMAKLLTLLRRGEIISPAYSD +RMYRNLGRQFW-DSHGLSQIPENVKVATKNGAVNR-SRSETVLVHAPGGE-YVYSIITKN +QKDETNEGFELLRKVSALLWHYy +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CLI2509 TaxID=1984801 RepID=A0A249LZR1_9ACTN +--AVADRIAAAFADAGVDGVVHAVDIDRGTET-GWEADRLVCTASVHKLCLLLALHRLAA +AGRIDLTERVECPVEGRTPGTGLAAMLDAPRMSLRDLAYLMIAVSDNAAADLLLARV-GL +EEVNRTTEALGLRRTRAVESFAATQEALDPAHGNRSTPRELTRLLAALWRDEFLPEPHGA +AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA +ADHVVPAADAVIGVVGRIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CEV 2-1 TaxID=2485153 RepID=A0A3N1TLC4_9ACTN +--TAEERIRAAFDEAGVEGFFLAREIDGDRTI-GVSADEPVVLASVFKIPVALAYAREAA +AGRLERTERLAVDARYRDGGIGTSGCADPIEMSLRDLVHLMLTMSDNAATDVVLARV-GL +DTVNGLLRELGLERTHLVGGCLELISVCVPELTTRSTARETAELLARIWRDEAGSAVACA +EVRAVMAQQIW-PHRLGSGFDDSYRLAAKTGTLP-GWRNEAGVIEHPGGGRWAVAVFTRS +DTPDNPRADRVIGQVARLAVDE- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces cavourensis TaxID=67258 RepID=A0A543VZ16_9ACTN +----ERTIRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD +AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GS +DAVDGMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDEAASPESCA +FMRAAMGTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Caproiciproducens sp. NJN-50 TaxID=2507162 RepID=A0A410PZB4_9FIRM +--KLNQFCKREIGRSGARVSLLVHDLTEGRDLiSIEAGHRVVSASTIKTAIMLAAFRLVL +DGKLSLSQTVRVPEEEVLDDTLVFDAGM-RECSLEEMITWMIVNSDNTATNVLIDVV-GM +EAVNGFCASLGLKSTGLQRKMLDGAA-VRSGRNNYTSAADQLLIYSALFRESILTPGLCG +LAKSILLRQRDCTMALRYLCGESVSFAHKTGGLDF-LRHDAGIFDLPGQA-YYFGCFVTG +CMDENPVAERLIGTLSKAVYESf +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A4P5V5E9_9CHLR +--DLNSALEAAISGIQGDFAWHIEDPSTGRAW-TRNAHEAYPAASTLKVAVFLRLLQLVD +DGRVGLDHQIRLRRWHQVGGAGVLQYFSPETLTVGEVATLMIILSDNTATNMIIDLT-GL +GSVNNLVTSLASRVTRINRYYGKPSMALPDGTHAMATANDLATIYREVLAGKILGPIGRQ +AFWQTLLRQQD-RAMAPRQFGPDILIAHKTGAID-GVRNDVGVFWLPD------------ +----------------------- +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A1Q5EVF4_9ACTN +----ERTIRSLFDDAGVRLHVAELDRPSARVV--VDPDEQVPMGSVYKVALMAAFCRLAD +AGRVDPRRRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA +EAVDAVCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPAETARLLRAIWTDEAASPEGCS +FMRAAMLTQPW-THRLASGFPDEVTVYGKTGTFGS-MRHEAGVVELGDGSVYTAVVFTQA +ARADLPRADAVIGAVARAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Jonquetella sp. BV3C21 TaxID=1111126 RepID=UPI0003ADDDAE +--RVASQIANRVYESGVQASVVLADPATGEQF-DLRGLQRLKSASLIKLPILWDLFARAE +EGSLNLSETIVVPSEKRVDGGLLHKFSASPTLRLEDLAVLAGTVSDNTAANLLMDRL-GL +DGINDRIRSLGMKSTSLERRMLDSGAA-KAGKDNWTTTCDVALFLSALTSTAGLSEAGKR +RIIDILSAQKL-QSKLAGAIPCDKVLAHKTGELP-GHEHDAGIFFPFGPRPAVLVVLTTG +LT-DRLDGVRFCSALGRLVYDEw +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonas sp. SG8_28 TaxID=1703357 RepID=A0A0S8AP27_9BACT +--TLAAQLRPLAESFRGKVGIYVRHLGSGAAV-ALDADSLFPTASMIKVPILIGVFDRLE +RGELGFLDTLVYTDSLLYPGEDILGSYRDSAVPLAQVLMLMITTSDNTAALWSQHLAGTG +TRINAWLGDHGFPHTRVNSRTPGRERDRQAYGWGQTTPREMAELLVTIREGLAVSPAASE +AMYRFLTRIYWN-GEALSQIPPWVQAASKQGAVDR-SRSEVVLVNAPSGD-YVFCVITKE +QEDEENEGYVLLRKVSALLWRYf +>[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Thermoanaerobacter ethanolicus CCSD1 TaxID=589861 RepID=C7IRL1_THEET +-qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT +DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRIV-GR +DNYIKFMEKLGAYVIPYS--------------NNVTSPRDMSMYMKNLLDYVNAHPDTAG +ELMYYLKNTIY-NDRISYPIPDGIEVAHKIGNLSN-VVNDAAIVFHPTR-PYILTVLANN +VDSDDSYAYTVIRQISKMVYD-- +>[subseq from] Peptidoglycan-binding domain 1 protein n=4 Tax=Thermoanaerobacter TaxID=1754 RepID=E8UVF3_THEBF +-qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT +DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRIV-GR +DNYIKFMEKLGAYVIPYS--------------NNVTSPRDMSMYMKNLLDYVNAHPDTAG +ELMYYLKNTIY-NDRISYPIPDGIEVAHKIGNLSN-VVNDAAIVFHPTR-PYILTVLANN +VDSDDSYAYTVIRQISKMVYD-- +>[subseq from] Peptidoglycan-binding domain 1 protein n=2 Tax=unclassified Thermoanaerobacter TaxID=2636821 RepID=B0K5X9_THEPX +-qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT +DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRIV-GR +DNYIKFMEKLGAYVIPYS--------------NNVTSPRDMSMYMKNLLDYVNAHPDTAG +ELMYYLKNTIY-NDRISYPIPDGIEVAHKIGNLSN-VVNDAAIVFHPTR-PYILTVLANN +VDSDDSYAYTVIRQISKMVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus opacus TaxID=37919 RepID=A0A3A9UT42_RHOOP +-------------------------IDDGGDI-AVGADDLVVLASVYKLPLLVALCRAFA +SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL +ESVERALSELDMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGSAVPGPQGE +FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA +ARTDLPVVDAAIGHAARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Rubrobacter radiotolerans TaxID=42256 RepID=A0A023X6K6_9ACTN +--DLEARIRAIAEIYPGEFGVVVRDPRTGETA-GLNPDQTFTAASLAKLPVLLALYGEAA +DGRLDLEEKIVMEAQDVQLGAGVLQNYPVGHMTLRECAELLIKESDNTAWVMLERRL-GR +ERIEHEIESLKLSGTDYAA--------------LTTTPEDVLRMLEAIADPDHTTPELSA +EMLAHMTDTAY-EGRIPEPLPKDVRVAHKVGTLND-TRSDAAIVFRQDRVDYMIVVIASG +GT--ERSATDAIRRISLSAYE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. DfronAA-171 TaxID=1839777 RepID=A0A1C4KKS6_9ACTN +--AVADRIAAAFADAGVDGVVHAVDIDRGTET-GWEADRLVCTASVHKLCLLLALHRLAA +AGRIDLTERVECPVEGRTPGTGLAAMLDAPRMSLRDLAYLMIAVSDNAAADLLLARV-GL +EEVNRTTEALGLRRTRAVESFAATQKALDPAHGNRSTPRELTRLLAALWRDEFLPAAHGA +AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA +ADHVVPAADAVIGVVGRIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A3M1JUJ7_9BACT +---LKTRLERMAADFRGEVGIYVHHPARGLTL-SIHGDDLFPTASMVKIPIMIGIYDRIE +KGELSLDSTLIFHRDSIHYGDAVARFAEGEDITLGKLLAHSITFSDNYASIWLQQLAGTG +TAINAWLADHGWEQTRVNSRTPGRQSNWEEYGWGQSTPEEMARFLLALRRGNVVSPRASE +DMYRYLCRSYW-DGEALSQIPPWVQAASKQGAVDE-ARSEVVLVNAPHGD-YVFCVMTNH +QTDQDNEGFVLIRRVSRLLWQTf +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. MD40 TaxID=2029590 RepID=A0A2A2SB68_9SPHI +--KLTVQLQNLLKDFHGRAGVYVHNLKTGKTA-AINSDTLFPTASMIKVSILNGVMDKIE +KGDLHYNQKLVYRDSLLYAGEDILGSFKNGDIQLSKVTMLMITMSDNTASLWLQKLV-GG +EYINNWLATNGFKVMRVNSRVAGREDMRKIYGWGVTTPYEMCRLFTLIRDGKAVSPAASE +RMYRTLNRIYW-DENALSQIPPYVQAISKQGAVD-ASRSETVLVNAPHGD-YVFSIITKN +NLTPQNEADILIKKVSALLWHYf +>[subseq from] Serine hydrolase (Fragment) n=2 Tax=SAR202 cluster bacterium TaxID=2030829 RepID=A0A5N9CKX7_9CHLR +--NLESTLDNIINQFEGVAGLSIRCLNNNKTI-SINGDDIFPTASSIKIHILTQLFTLED +KGTIDLAKRVRFTQDMYGAGSGVIHFLENEPFTILDIAILMMLVSDNTATNMCIDLA-GM +QETNNLIKDLGLSKTKLGRKMMDPD-AINRGEENISTPNELTKMMELLYQKKP-SPKVAE +NVLNIMSKPKS--AYLNKAIGPHTKVANKPGGMDK-VRCDVGIVY--------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Dyadobacter psychrophilus TaxID=651661 RepID=A0A1T5CAR3_9BACT +--KLVKKLEAAMAGFKGDAGIYVRNLKTNRVA-EVNADSVFPTASMVKVPILCGILDKIN +RGEVAFNQELIYRDSLKYDNGIVGSFRDSTRIALPKIVHLMISQSDNTGSLWLQAMAGGG +ATINQWLDNNGFANIRVNSRTPGRKENQAKYGWGQTTPREMAELVAMIRNGKAISPAVSE +RMYRYLGMQFWDGESI-SQVPPTIKIAAKSGAVNQ-AKSEVLVIHAPHGD-YVFCVATKN +QEQKNNEGYVLIRKLSAIIWNHf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CB03238 TaxID=1907777 RepID=A0A1X1NF60_9ACTN +------------AQAGVEGYVHARDLDTGEEF-GHGADTPVVLASVFKIPIALEYARQAA +AGELDPARRHTVTPAYRAGGSGTDGCAYDVEMSARDLAFMMTTISDNAATDLLLDVV-GP +DRVRRTLDDLGFPGFGFSSSAA-LDDACAPGSSPSSTPREVTALLAAIWRDEAGPASACA +EVRDIMGQQVW-QHRLVSGFPAGMRLAGKTGTDF-AVRNEAGVIEYPDGKRYAVGVFLRT +STAAQPLADRAIGRAARIAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter ginsenosidivorax TaxID=862126 RepID=A0A5B8VWA3_9SPHI +-kKLTAQLQDAVKGFHGQAGIYIQNLKTGKTV-AINADTLFPTASMIKVSIQCGLMDKIE +KGELRYNQKLVYRDSLLYAGEDILGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GG +DYINNWLQQNGFKVMRVNSRVAGREAIRKIYGWGVSTPYEMCRLFTMIRKGEAVSPAASE +RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSVITNH +NTDQSNEAGLLIKKISALLWHYf +>[subseq from] serine hydrolase n=1 Tax=Rhodohalobacter halophilus TaxID=1812810 RepID=UPI00083F9A1F +-----EAIRTLAESFNGDVGIFVKDLETGKEF-EFRADDVFPTASMIKIPIMVGVFDKIE +KGELKYQMKLEYGPESEYEYSGISNLESGTEVTLSLLVHLMMSVSNNTGSLWNQYLAGTG +TEINSLMEELGFEHTRVNSRTDGRSEAFQMYGWGQTTPREIATLVEKIYKGEIINKHASE +QMFRVMSRNHW-DGEALSQIDPVINVASKNGAVS-ASRSEVLLVNGPSGD-YLFSVITKN +QEDRDNEAWVMIRELSSILYRHf +>[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Thermoanaerobacter italicus (strain DSM 9252 / Ab9) TaxID=580331 RepID=D3T4F6_THEIA +-qELKNNIQALISQYPGKYGVYFIDLNTGQTL-EINGYDSFIAASTYKVPLNFYLYTLIT +DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR +DNYIKFMEKLGAYVIPYS--------------SNITSPRDMSMYMKKLLDYVNAHPDTAG +ELMYYLKNTIY-NDRISYPIPDGIEVAHKIGNLSN-VVNDTAIVFHPAR-PYILTVLAND +VDSDDSYAYTVIRQISKMVYD-- +>[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Thermoanaerobacter mathranii subsp. mathranii (strain DSM 11426 / CIP 108742 / A3) TaxID=583358 RepID=D7ARJ7_THEM3 +-qELKNNIQALISQYPGKYGVYFIDLNTGQTL-EINGYDSFIAASTYKVPLNFYLYTLIT +DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR +DNYIKFMEKLGAYVIPYS--------------SNITSPRDMSMYMKKLLDYVNAHPDTAG +ELMYYLKNTIY-NDRISYPIPDGIEVAHKIGNLSN-VVNDTAIVFHPAR-PYILTVLAND +VDSDDSYAYTVIRQISKMVYD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CFMR 7 TaxID=1649184 RepID=A0A0M4DHD5_9ACTN +----ERTIRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD +AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GS +DAVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETALLLRAIWTDEAASPESCA +FMRAAMGTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia sp. RB56 TaxID=2585199 RepID=UPI00129735D8 +-----------FEQAGVRGVLHARCLGTGAEI-DLGADDPVVLASVVKVPLVLEFGRQVA +AGQLDPADRVRAVAATRLGGTGLAGCADDVELSLRDAAYLALSVSDNTAADLLFDRV-GL +DNVRSLLRELGLHRTRIVGAPRDLVRALDPLRTNASTPREMTGLLAAISRDEAGPPEVCR +WLRGLMSQQVN-WYRLAAAFPPEVAVWGKTGTLP-GLRHEIGVVEYPDGGRYAVAVFTRA +GTQRLPQVDRAIGVAAREAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. WZ.A104 TaxID=2023771 RepID=A0A2A4KTK1_9ACTN +---TLQQIHSAFSEACATGWLHAVDIDSGAEV-NANADGAVVTASVHKLCLLLALHQQAE +QGLLDLTEQVECATDGRAAGPTGLAVMLDPVISLRDAAYLMMAVSDNAAAEVILERV-GL +DAVNAATTRLGLTHTRAVHTFAHTLAALDPARTNRSTPRDMTRLLCALWRDEACSPEGCA +AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAIAVFTRA +VNATLPSVDAVIGTTARLAVD-- +>[subseq from] Serine hydrolase n=2 Tax=Cyanobacteria TaxID=1117 RepID=A0A1Z9LHM9_9CYAN +---LSKRWNQLAAQQDLQASAFMLILDDGRYA-AMAADRAMPAASSIKTPILLAVLEQLD +XGXLQWNEPLTLTKELVGGGAGWMASRPIGSFPTYEVATEMIRVSDNSATNLMIARAGGQ +QAINERFQELDLPATVVNNWLPDLDGT------NTTSARDLSRAIALVDSGEVLAPRSRD +LFREVMSTSVT-NTLLPRGLLKGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG +PFN-DPRSTELIRQLAAAMA--- +>[subseq from] serine hydrolase n=1 Tax=Clostridiaceae bacterium TaxID=1898204 RepID=UPI00130EC88A +--TLEKRIEAELMSYDGKMGIYLDDF-HGNVI-SIDGDEAFETASAIKTYILVCLFDQVE +KGNKSFEDVIEYKQEHVVDGSGVLPALEPGALRVKDAATFMIIVSDNIATNMIIDYL-GL +DTINQCIRDLGCRDTVLHNPIH-FE---KYDKLGTSTPRDYASIFTRLAKGELISRSADE +KMVEIFKKQHY-NTMITRDFPAVISVASKSGSMD-ACRNDGGIVFTPYG-PYAIVMFHKE +FSDASHPATMFGARVSRMILDQf +>[subseq from] hypothetical protein n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0002DD1BDF +----ERTIRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD +AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GS +DAVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETALLLRAIWTDEAASPESCA +FMRAAMGTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=candidate division WWE3 bacterium RIFCSPHIGHO2_02_FULL_38_14 TaxID=1802620 RepID=A0A1F4V8G1_9BACT +---LSHLLDKELAKLNGSVGLNVKFLSSNEIY-TYNGKTQFWSASVIKIPIALTFYEQIK +EKNINDTEKVKITEDNYVLGSGIAKLLDKNNYTFKDLITLMLVVSDNTATNQIVDFI-GW +ESVEKYMKEIGLENTTFKHKMMI--K--AGRGPNLTTPEEMTTLLERMYKNEL---PGSE +IVLKIMQEQLD-RTRIPQLIPNEIPISHKFGTLPE-ALHEVGIIYSKN--PFIFCFFSDD +QK-DKKLTNEVLSVCAKHCFD-- +>[subseq from] Uncharacterized protein n=1 Tax=Nonomuraea sp. KC333 TaxID=2070368 RepID=A0A2W2ENL5_9ACTN +-------------GVRVSVGLADLSRPNGRST-ILGSTASYNPASVIKLSLLATLMRQVD +RGLVSLDAPVTVSPYMVVGGSGTIQDEPMPFTTVRELARRMVVVSDNTATNVLLYYV-GI +PTVQALLDDLGLRTMKFNRQMF--PGALISAPTNVLDAADTLALLKATYSGRLLSRKSTE +QIVDWMRHQEV-DTKFGAVLN-GRPIAHKTGETGN-VTHDVGYFLVPGHE-TAVVVLTEV +TTEAQRIGNPIVQNIGLAVYDH- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFOXYB1_FULL_47_11 TaxID=1798401 RepID=A0A1F6BEJ3_9BACT +---LKKKVQETIDNTWNNYSVYVVDFNSNFTM-GINENEIFTAASVNKLPIMAAVYYKAQ +KGEVNFDQIVTLQPEDIQDTGSIRYDAPGTTYSVKTLMRLMMQKSDNTAAFLLGNYIVEL +PAIQSIISEWGLTQTDMVN--------------NKASNHDMYILLNKIYGNNITNAALTA +EMLGFMRDSDF-EDRLPGELPKEATVYHKIGTGDGGIIHDVGIVVNGKT-AYYVGIMTAD +IP-DPENAAKLEAKVSKIIYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Caldanaerobius fijiensis DSM 17918 TaxID=1121256 RepID=A0A1M5CIK2_9THEO +-sALKAKLQRYINTRPGQISVYVHDLTTGQTL-SIGGDRVYAAASTIKLPLVLYLYEQAA +AGKVDLNTKLTYTPQYYMQGTGILQGQPFGGYTIRELSRLAIEYSDNVAWQMLLDYA-GQ +DNLTAFEKSLGAKATGLVNGLS------------VTTPKDMDIYLSELLTFRDENYDLGN +EVLYYMEHSIF-SEGIPQELPSGVVVAHKMGALDD-KFHDVGIVFG--NRPYIITIFTEN +GWED--ASLQTLADISRIVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=uncultured bacterium TaxID=77133 RepID=K2DJJ4_9BACT +--DLKNEIDKITKDKKGFYSIYYKDLKTGSFF-GIDEHQIETGASVNKLPIIAALYYLDK +QEKISLDDKITILEKDVQNTGSIRYQKMPQTYSLRNLAKLALKQSDNTASYVISLKI-GE +ENVQKLVDSWGMKQTNMKN--------------NKTTAFDMSLLFEKIYTNQITDPARTK +ELLEFMTETDF-EDRLTKGLPSNVKIYHKTGDEE-GFVHDVGIIETEKGT-YYLGVMTSD +IGENEEETKNTIAKISRKILE-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces tsukubensis TaxID=83656 RepID=A0A1V4AB41_9ACTN +-----RAIRSMFADAGVRGWLHVADVHRTARV-TVDPDEPVPVGSVYKLPLMAAFCRLAD +SGAIDPLLRVTLGPDDRMPPTGLSILRDPVTVSLRDLVVLMMSVSDNTAADAVLRRV-GT +AAVDELCREVGMPDTRILGGAATTFEVYDPLSKASTTPSDMARLLRAIWTDGAASAESCA +FMRETMGRQAW-SHRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELADGGTYTAVVFTQA +ARADLPRADAVIGAAARAAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. SAT82 TaxID=2024887 RepID=A0A2E2G888_9SYNE +--------REIAATQXLMXSAYLLILDDGRYA-QLNANRPMPAASSIKTPVLLASLERID +AQDLSWNEPLELTEDLVGGGAGWMASRPVGSFPTYEVATEMIRISDNSATNLLIERAGGQ +QVVNERFRSLGLPATVINNWLPDLDGT------NTTSAHDLSRSIALVDSGDLLSPRSRD +LFRQVMETSVT-NTLLPTGLMQGYRVLNKTGDIGI-AYADAGLIELPXGRRAVAGFLVKG +PFXD-PRSTNLIRAMAKAMA--- +>[subseq from] Serine hydrolase n=1 Tax=Jiangella asiatica TaxID=2530372 RepID=A0A4R5CQZ8_9ACTN +--------KGAFADAGVTGHLHAVDIDSGAEA-GLDADAPVVTASVFKVPVLVELCRQAA +AGERSLTDRVRVPAAPRTLGPTGLSVMLDDILSLRDLAYLMMSVSDNHATDVLVRLL-GI +DRINAGLAALDRHDTVVMGDCDYLFSALTAEQTNRSTARDTTALLRRVWTDDGLAPDAAA +EVRRIMALQVW-PHRLTSGFPDDVKIAAKTGTLSH-VRNEAGVVEYPDGSRFAVAVFLRL +PGRENPAADAVIGRAARIAVDH- +>[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000365ECD6 +------TVRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD +AGRLDPCHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLREV-GT +DAVDRMCAGLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDRAASPASCA +FMRAAMGTQPW-AHRLASGFPDDVAVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. CH32 TaxID=2530383 RepID=A0A4R4ZJS6_9ACTN +-------------AHGVRVSVGLADLSNGQSA-ILGSVASYNPASVIKLSLLATLMRQVD +RGLISLDAPVTVSPYMVVGGSGTIQEHMPFNTTVRELARRMVVVSDNTATNVLLYYV-GI +PTVQALLDDLGLKTMKFNRQMFP--GDLITAPTNAIDAADTLSLLKATYSGRLLSRTSTD +QIADWMLHQEV-DTKFGAVLA-GKPIAHKTGETGN-VTHDVGYFLVPGHE-TAVVVLTEV +TTEAQRIGNPIVQNIGLAVYDH- +>[subseq from] Uncharacterized protein n=1 Tax=Leucobacter komagatae TaxID=55969 RepID=A0A0D0IQD6_9MICO +----------VAEDAGVFAFAHARDIDTGAEV-GFDSDAPTVTASVFKVPVLVEYVRQVS +AGELDPAQRVRFLPADATLGPTGLSVFSDEAWSLRDVATSMITVSDNAATDIVTGMV-TV +DRVNQTMRELGLPGTQLTGDCARIFEAATPEKTNRTTPREATSLLQQIWTDAAASPEACA +EARRILGLQVW-PHRLSSGFPDDVKISGKTGTLGM-VRNEIGVVEFPDGTRHAIAVFLRG +KTSRNPAADRAIGDIARLLSD-- +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. PAMC 26640 TaxID=1300914 RepID=A0A142HZM3_9SPHI +-kKLTAQINTAIKGFNGKVGIYVQNLKTRKTV-GINQDTLFPTASMIKVSILSGVMDKIE +KGELKYNQKLGYRDSLLYAGEDLLGSFKDKDIQLSKVAMLMITMSDNTASLWLQKLV-TG +EHINNWLDRNGFKNMRVNSRTPGRQAMQKIYGWGVTTPYEMCRLFTLIRNGQVVSPAASE +RMSRMLNRIYW-DNTALSEIPPFVQALSKQGAVDD-SRSETLLVNAPHGD-YVFSVITKN +NKTPENEADLLIKKVSALLWHYy +>[subseq from] serine hydrolase n=1 Tax=Streptomyces niveus TaxID=193462 RepID=UPI00084CBD44 +----RDRIRAAFAAAGVTGWLHAVDIDSAAQI-EVGADQPVVTASVHKLCLLVALHQHAE +AGRLALTDQVESPAGGRTPGPTGLSAMLDPAVSLRDAAYLMMAVSDNTAAELLLARV-GL +DAVNETTERLGLTRTHAVQTFGEFITALDPARTNRSTPRDMTRLLGAIWRDEACTPEHSA +AVRRLLGLQVW-PHRLASGFPDEVHVAGKTGSAPT-LRNEVGVIEYPDHGRYAVAIFTRA +ASAALPAADAVIGTTARIAID-- +>[subseq from] Beta-lactamase class A n=1 Tax=Thermoanaerobacter uzonensis DSM 18761 TaxID=1123369 RepID=A0A1M4W3N5_9THEO +-qELKNNIQALISEYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT +DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR +DNYIKFMESLGANVIPYN--------------SNVTSPRDMRMYMENLLNYVKAHPDTAG +ELMYYLKNTIY-NDRISYPIPDEIEVAHKIGNLSN-VVNDTAIVFHPTK-PYILTVLANN +VDSDDSYAYTVIRQISKMVYD-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus opacus TaxID=37919 RepID=UPI0002A247FF +-------------------------IDDGGDI-AVGADDLVVLASVYKLPLLVALCRAFA +SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL +ESVERALSELDMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGSAVPGPQGE +FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA +ARTDLPVVDAAIGHAARIAVT-- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Faecalibacterium TaxID=2646395 RepID=A0A1Y3WNY6_9FIRM +--TLEKRIAAELYSYRGQMSVYLDDL-RGHTV-EIGADEPFETASTIKAYILAALYLQAS +RGQASLEDRITYQPQHFVDGSGMLRAGVGAALKVKDAATLMIICSDNIATNMIIDYL-GL +DQINRCIRELGFAHTVLHNTLHF-DR---YSQLGTTTPRDYGSLFAQVARGSLVSPQASR +EMLTIFRAQHY-NTMLTADFPPYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKN +FEYNAHPAMVYGARVSRMVL--- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. F-1 TaxID=463642 RepID=A0A1K2FPM5_9ACTN +---IEETIAEVFAAGGCRGSLCALEVDGPGRV-SVAGGEPAVAASTFKIAVGLEFFCQAA +QGELDPAERVVVSPAGATPGQGLCITEDPVEISLRDVARLMLTISDNTAADVLIRRV-GI +ERIRARLTGLGLTGFHLPGTIHELDTGMRPGRISSATADDLAALLRAVWRDEAGPAQACA +QLRRTMGQQRL-TRKIAAGFGPEVLVASKSGTVPGGVSNDVGVVAFPDGRRYAVAVLTRS +LTPGAPTREDVLGTAARVALDH- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Hydrogenedentes bacterium CG07_land_8_20_14_0_80_42_17 TaxID=1974588 RepID=A0A2M6Z723_9BACT +----NLKLSELISKCPGTPSIKILFLNSGYEM-EFRSGKVVRAASVIKLPICVAVMSLCR +KGKGSLPEPISLVEEDRTSGSGILRHRFNRDYTVEELIKLMILESDNTATNALIRRF-GL +EEIQNEFEKAGLIKTKLKHRILEASED------NPISSSEIVDLLSAIADESSIHPDDRR +WIFDLLKQTSP-GARLGRYLPDEAKIAHKTGTLRR-EVHDAGIIETDSNK-IIVSALIEK +AK-SRKEAERWLGRLGRLICE-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. S2-17 TaxID=1990687 RepID=A0A2S2BV89_9NOCA +-------------------------------V-TVDGDDLVVTASVYKLPLLVALCRAFD +AGTLSPTSTVRVNPADCTPPTGVSMFRDPVVMSWRDLALSMMTVSDNAAADLILGGV-GL +DAVDRVLTDLCLTRTRIVGGTADAHRAYDPSYASATTPREMTALLDAIWTDRAVSPVQGE +FIRQVMAAQVW-QHRIRSGFPADVTVAGKTGTIG-AIRNEAAVVTFPGEIPVAVAVFTRA +ARADLPMVDQAIGRAAQIAVT-- +>[subseq from] Beta-lactamase n=2 Tax=cellular organisms TaxID=131567 RepID=A0A094YN85_9PROT +---LAQSISKTVKAQPGHFAVYAALSGYSPAV-CLNCDDLINAASTIKLFVLDAAYDAFT +KGTLHPQDTVTVHNRSLVGTGTFAYAQAGKPVPVSELLRVMIQYSSNLATNLMVEKL-GV +MPIRSVVKAQGLDGIVFGRMIEDFDAN-DKGIRNQVSARGLGAFLQKLDNGQIVGKAQSQ +SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGRHYILVVLTSG +LP-DEQAGIKVLNTLSSQTYAYf +>[subseq from] Serine hydrolase n=1 Tax=candidate division WOR-3 bacterium JGI_Cruoil_03_44_89 TaxID=1973748 RepID=A0A235BVI4_9BACT +--VLQRQIEASVENFQGDVGIYVRHLSKNITA-GINEDDLFPTASMIKVPILIKIFDKIE +KGELTIDSTVIYYKDSINYGDDAISRFKDGEISIGKLMAHMITFSDNHAGIWLQELAGSG +TEINEWLNQEGFRSTRVNSRTTGREDDYEQYGWGQTTPREMAELLVMIREGRAVSRRASD +DIYRHLTRIYW-DGNALSQIPPTIQVASKQGALDQ-SRSEVVLVNAPHGD-YVFCIITRD +QKDTSNEGSVLIRTVSNLLWNYf +>[subseq from] serine hydrolase n=1 Tax=Nocardioides jensenii TaxID=1843 RepID=UPI0012FC79B0 +-----KDILKEAAAVGVRVWLQAQSVRSVTQV-GVGPDIPVVLASLLKVPVALELARRAA +SGEFDLDRQVTLSPADLTPPSGLGTLRGPVTLPVRDLAVLMLSLSDNAATDFLLSMV-GR +DAVERLLGELGLSRTAVPQDCAEIIRALDPDRTCRSTARETVSLLRAIWQNEAGPSAACA +NVREWLSHQAW-DNRMASGFEDDVEIASKTGTLP-GLRNEAGVVTYPDGGAYAVAVFTRD +EDSRNSSRDHFIGRAARLAVE-- +>[subseq from] Serine hydrolase n=2 Tax=Luteimonas aestuarii TaxID=453837 RepID=A0A4R5TRT0_9GAMM +-----------------SVGLADVSRSDGAQR-IIGSTDSYNPASTIKLALLATVMRQAD +RGLLNLDAPIGISPYMVVGGAGDLQRQAMPFTTVRDVARRMVVLSDNTATNVLLYYV-GL +PTVQALLDDLGLQTMRFNRQMFPGEK--IGEPANAIDTADTLSLLHAIYIGDLLNEQSRR +QVLDWMLAQEV-DTKF-GALPDTSRIAHKTGETGT-VTHDVGYFLVPGHE-TIVAVLAEV +TTETMRIGNPVVQDIANAVLD-- +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC333 TaxID=2070368 RepID=A0A2W2EL52_9ACTN +----------VFADAGVRGFLHAREVDGDAET-GLDPDEPVVLASVFKIAVALEYARQAA +AGEIGRTERLTVTSADKDGGIGTSGCQDDVSLTLRDLAHFMITMSDNAATDVLLRRV-GL +DRVNGTLAALGLRRTRLIGGCAELFDAVRDPARTTATSREITTLLGLIWRDEAGPPEACA +EVRRLMGEQIW-PHRLSAGFPDEVKVSGKTGSLW-GVRNESGVVEYPDGRRYAVAVFVRS +EVERLPHADAVIGRAARLAVEQ- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=A0A193C0Q4_AMYOR +-----AEIEAVFANAGARGFVHAREVGGGPEV-GVSADDPVVLASVFKIPVAVAFAREVA +AGRLDETERTRVTARYRIGGVGTAGCADDVEMSWRDLAHFMLTMSDNAATDLIYHRL-GQ +DKIDQVLADLGLVRTRLIGCCEDLFAVVDPERTTSSTPREITTLLDAIWTDRAGDPAACE +RVRTIMAQQIW-PHRISSGFPGEVAIAAKTGTLPS-VRNEAGVVTHVDGRRYAVAVFTRA +ESDRLPAVDSAIGEAARLAVEH- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces griseus TaxID=1911 RepID=UPI0008407702 +--------RGMFDDAGVRGWLHVADLHRSAQV-TIDPGDQLPMSSVYKVPLMAAFCRLAD +AGRIDPGRRLTLGPDERVPPTGLSVLRDPVTLSLRDMVVLMMTISDNTSAHAVLRAV-GP +EAVDATCRDLGLPDTHIHGGVVSTFSVYDPASKASTTPADMARLLRAIWTDRAASEDRCA +FMRGVMRRQAW-SHRLGSGFPDDVTVYGKTGTFGS-LRHEAGVVELADGSTYTAVVFTQA +ARADLPRADAVIGAAARAAVE-- +>[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Thermoanaerobacter uzonensis TaxID=447593 RepID=UPI0009331BF4 +-qELKNNIQALISEYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT +DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR +DNYIKFMESLGANVIPYN--------------SNVTSPRDMRMYMENLLNYVKAHPDTAG +ELMYYLKNTIY-NDRISYPIPDEIEVAHKIGNLSN-VVNDTAIVFHPTK-PYILTVLANN +VDSDDSYAYTVIRQISKMVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Spirosoma pollinicola TaxID=2057025 RepID=A0A2K8YV55_9BACT +--SLERQLRSALSGFRGDAGVYVYNLRTGKTV-AINADTLFPTASTIKIPIQCGLFDKLH +KGELTYTEPLVYKDSLHYDDGIVGSLKDGTKIPLSEVVMLMETVSDNTGSLWCQALAGGG +TAINNWLETNGFHQTRVNSRTPGREASRTQYGWGQTTPREMANLLTYIRQGRAVSPDASD +EMYRNLGRQYW-DNDGLSQIPSEIKTACKNGAVNQ-SRSEVVFVHAPHGE-YVYCIMTKN +QKERTNEGFELLRNVSAILWHHf +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter gossypii TaxID=551996 RepID=A0A5C1IJG0_9SPHI +-sKLTAKLNEAVKDFQGQVGIYVHNLKNGKTA-EINADTLFPTASMIKVSIQCGVMDKIE +KGELRYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GG +EYINNWLNQNDFKVMRVNSRVAGREAIRKVYGWGVSTPREMCRLFAMIREGKAVSPAASE +RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH +NKTPDNEAGLLIKKVSALLWHYf +>[subseq from] Possible beta-lactamase family protein n=1 Tax=Synechococcus sp. (strain CC9605) TaxID=110662 RepID=Q3AI91_SYNSC +--------ELAAQQSNLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD +QGTLQWNEPLTLTEELVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLMIARAGGM +EAINARFQELDLPSTMVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD +LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG +PFN-DPRSTELIRQLAAAMA--- +>[subseq from] serine hydrolase n=1 Tax=Eggerthellaceae bacterium zg-886 TaxID=2682776 RepID=UPI00140792DE +--DIEASLSQLIEDSGASASFAYRYLSSGWDF-SVHGKESHTAASMISLAVLTQLFDRID +AGDLSLDDEYELTEEAIVGGNGRLQDDPGTAYSLRDLVWYSIVESDNTATNMLIDIA-GM +DAVNSEVARQGLEGTSLERHMMDTEAQ-KEGRENRMAADDAAAILNAIAQGAFYNEELSD +FAYDLLSQQKS-DSAVKGVLPEGATYAFKSGSLEN-VYNEGGVVFG--EHPYVFVAFVEG +VD--EEEATALVKDAAALV---- +>[subseq from] Uncharacterized protein n=2 Tax=Bacteria TaxID=2 RepID=A0A358UXT9_9BACT +----NLKLSELISKCPGTPSIKILFLNSGYEM-EFRSGKVVRAASVIKLPICVAVMSLCR +KGKGSLPEPISLVEEDRTSGSGILRHRFNRDYTVEELIKLMILESDNTATNALIRRF-GL +EEIQNEFEKAGLIKTKLKHRILEASED------NPISSSEIVDLLSAIADESSIHPDDRR +WIFDLLKQTSP-GARLGRYLPDEAKIAHKTGTLRR-EVHDAGIIETDSNK-IIVSALIEK +AK-SRKEAERWLGRLGRLICE-- +>[subseq from] Serine hydrolase n=1 Tax=Acidaminococcus sp. AM33-14BH TaxID=2292909 RepID=A0A3A5RHZ6_9FIRM +-dALQKDVEMYLAKRPGKTAVSCWLLTEKQGF-SIGGKNELPSASLIKLLVLVELCEEVR +RGRANLKEAISILGSAITGGDGIIKEKIGHTFTLEELATLMIIVSDNEAANQLIDRL-GM +KAINERAKKLGLAQTHLGRLMMADAS-GEKERDNWTSADDTVHLLRVICETAKTGSPLGR +WMISLLARQQQ-EGGLRRNLPDFVQVAHKCGNLA-GVEHDAGIFFG--KRPYLLAVLTTE +QPASY-VGRETIG---------- +>[subseq from] Serine hydrolase n=1 Tax=Balneolaceae bacterium TaxID=2053516 RepID=A0A6C1PAQ3_9BACT +-rQLQHSIEGLLARFNGDAGVYIRHLPSGREI-AVNADTVFPTASMVKVPILAALFDRIE +NGDLEYREKFYFDGQHNYGFRDVISNMTDSSVYLDMLIHLMMSTSNNTASLWNQHIAGGG +EGINVWLGENGFEHTRVNSRTPGRGEAQARYGWGQTTPREMARLLEMIYLGEAVNPHASE +KMYRIMTRNFW-DGEALSQIPPYINVASKNGAVSR-SRSEVLLVNAPSGD-YLLCIITKN +QNDSENEGWVLARTISRLAWQTf +>[subseq from] Serine hydrolase n=1 Tax=Kribbella pittospori TaxID=722689 RepID=A0A4R0KW46_9ACTN +---------AYAGELGAEIWLHARDLATGRTV-GVDAETPVVTASVLKVPVALELARQAV +AGEMDLAERITVPAEGLVASPYGLAMHRDPTISYNDLALLMMVISDNVATDLVIDRV-GK +DRVAALLAELGLPGTAVPQNCAEILAALDPAATDRTAPDEITSLLAGIWRDEAADPEACA +LVRGWMGKQVW-PHRLSSGFPDDITVSGKTGTLPL-VRNEVGVVEFPDGGRYAVGVFTRA +ADPNAPQFDGLIGWAAAQ----- +>[subseq from] Beta-lactamase n=1 Tax=Synechococcus sp. KORDI-52 TaxID=585425 RepID=A0A076HH07_9SYNE +-------VELAEEQSDLDASAYMLILDDGRFA-AMQAEVPMPAASSIKTPILLAVLELLD +QGTLRWNEPLTLTEELVGGGAGWMASRPLGSFPTYEVATEMIRVSDNTATNLMIARAGGM +DEINARFEALDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGEVLGPRSRD +LFREVMGTSVT-NTLLPKGLMRGYRIYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG +PFN-DPRSTELIRRLAAAMA--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. 4R-3d TaxID=2559605 RepID=A0A4Y8XXV1_9ACTN +--------------LDARVWLHARCVDCGRGT-GHGQDEPVVLASVVKVLLALEFWRQAA +AGQLDPAEVVVVRAADRLGGTGTAGFHDDARLSLRDLALLMMSVSDNTAADILFRRV-GL +DTVQALARQLGLDRAQVTGAPREVLEALDPARTTSATPREMTRLLSLVWNDRAGPAVACA +GVRDLMAQQVN-GARLGAAFDRFTTVVAKSGTLP-GVRNEIGVVTCPDGARYAVAVFTRA +TSTRRPDLDAAIGEAGRGAV--- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006C13483 +-qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNAATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter oryzae TaxID=468058 RepID=A0A316HIY5_9SPHI +-hKLAVKLQDAVKGFRGHVGIYVQNLKTGKTA-EINADTLFPTASMIKVSIQCGVMDKIE +KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDIQLSKVAMLMITMSDNTASLWLQKLVGGP +-YINNWLEQNGFQVMRVNSRVPGREAIRKIYGWGVTTPREMCRLFTLIREGKAVSAAASE +RMYRNMGRIYW-DEDALSQIPPFVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH +NTTPNNEAGLLIKKVSALLWHYf +>[subseq from] serine hydrolase n=1 Tax=Anaerotruncus TaxID=244127 RepID=UPI0013632499 +-----EQILNELSQMEGKVGFYYHNLVTGETY-GYREKEPFLPASVIKFPLMAAILLLRS +RGEADFREEILIHQDQKVPGCGAVQHITGEVLDMETLGKLMITISDNTATNALLRHY-TV +PKIREAFLELGLIGTQFNRELWDLERE-ARGINNYFVPEEIGILLEKIYHKTLVNEESSI +WLDDIMRQQQI-NHKMGGHLIMDYPMAHKTGDEED-KAHDVGIVYAK--QPFVVCFASNE +VD--VPMYEDFIRRTTKALVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga polysaccharea TaxID=1293035 RepID=A0A561PTX3_9BACT +--RLTAILQPMLQSFHGVAGIYVHHLGKDRTV-AINADTVFPTASMIKMVIQVGIFNKLA +AGELQYHQNLLYRDSLLYKGEDILGSFRDSEIALDKVVMLMLTMSDNTASLWLQSLAGGG +AVINQWLAGQGFEHLRVNSRTKGREANREAYGWGQTSPREMARLMEMIYRGEVINKTASE +RMYRNLTRNYWDAQGI-LQVPPNVRTASKNGAVDE-SRSEVIMVNAPRGD-YVYCMITKN +NKNHDNEAWQLLRKVGFAIWQYy +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora chokoriensis TaxID=356851 RepID=A0A1C4U6Y3_9ACTN +---------VIFAAAGVTASLHAVDLDAAREV-GVRADEQVVIASIFKVLLVLEFARQVE +AGQLDPTERVLVTAADRLGGWGLAGCVDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLTRTRIRGGPRELVEVFDPAHTTSSTAREITRLLTMIWRDEAGPAAACA +MVRTWMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA +DQSRRIDVDLAMGEAARTAV--- +>[subseq from] Serine hydrolase n=1 Tax=Dyadobacter luticola TaxID=1979387 RepID=A0A5R9KXY7_9BACT +-kKLTNKLVQALTGFHGEVGVYVRNLKTGKVA-LVNADTLFPTASMVKVPILCGVFDKIN +KGELTFNQELIYRDSLKYDDGVVGSFRDSTKIALPKVVHLMISISDNTGSLWLQALAGGG +EAINSWLDTNGFSQTRVNSRTPGRKAFQARYGWGQTTPREMAELVTMIYNKKAIEPEASE +RMYRYLGMQFW-DGEAISQIPPYIKTAVKNGAVNQ-ARSEVLVVNAPHGD-YAFCITTKN +QQQKDNEGYALIRKVSAIIWNHf +>[subseq from] serine hydrolase n=1 Tax=Jiangella asiatica TaxID=2530372 RepID=UPI0013A5C64E +------------ADAGVTGHLHAVDIDSGAEA-GLDADAPVVTASVFKVPVLVELCRQAA +AGERSLTDRVRVPAAPRTLGPTGLSVMLDDILSLRDLAYLMMSVSDNHATDVLVRLL-GI +DRINAGLAALDRHDTVVMGDCDYLFSALTAEQTNRSTARDTTALLRRVWTDDGLAPDAAA +EVRRIMALQVW-PHRLTSGFPDDVKIAAKTGTLSH-VRNEAGVVEYPDGSRFAVAVFLRL +PGRENPAADAVIGRAARIAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Niastella yeongjuensis TaxID=354355 RepID=A0A1V9EX08_9BACT +-hRLQQKIQETVKGLDGDIGVYVKNLRTGKMA-AFNADTIFPTASMVKVTILIGIEDKIE +KGELDYHQQLEYRDSLFYAGEDILGSFKNGEIGLHKVMMLSLTTSDNTASLWLQSLAGNG +TRINQILDSLGLVNTRVNSRTPGREASRQQYGWAQTTPREMGTLMEKIYNGEVISKKAGE +KMIRLLGRNYN-DEQAIAEIPPYIFVASKNGCVN-ASRSEILLVMAPHG-PYIFSVETKN +LKDNSNEAWLLTRKLSALCWNY- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. B27 TaxID=2485015 RepID=UPI000FD9CC6A +---------SLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD +AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLAVQMMSISDNTAAHAVLRAV-GT +DAVDRMCADLGLLRTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDEAASPESCA +FMRAAMGTQPW-THRLASGFPDDVAVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] serine hydrolase n=1 Tax=Terrisporobacter glycolicus TaxID=36841 RepID=UPI0011DE3273 +------------KSIEGDVSFYYKNLITNKTV-AYNEEKIMLAASVIKITVLVEAFKQIK +EGKIKKEELFITCEDDKVPSCGALNYMREGLVTLEDLYILMIILSDNYATNMLIDKL-GM +DNINNTIKEIGLKNTVLNRKMFDSKKATLG-LENYISASDVGYLLEKMYNKDLIDKKSSE +EMISILKNQRLNGKMFLQNLKPKIEIAHKTGEDTN-ITHDVGIVFAK--EPFIVCFCGNN +V--NVPEYERLIQDITYDLY--- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. MED-G133 TaxID=2518986 RepID=A0A520LPG6_9SYNE +---LSARWRAIAAQKDLEASAYMLLLDDGRFA-QMNADRPMPAASSIKTPILLTALQRID +AGDLHWNEPLLLTKELVGGGAGWMASRPLGSFPARVAATEMIRVSDNSATNLLIERVGGQ +QTINQLFQDLGLMATEVNNWLPDLDGT------NTTSAYDLSRSIALVDTGETLSLRSRD +LFREVMATSVT-NTLLPTGLMKGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG +PFND-PRSTNLIRAMAAAMA--- +>[subseq from] Serine hydrolase n=1 Tax=Oceanobacillus bengalensis TaxID=1435466 RepID=A0A494Z079_9BACI +-----------TSKVP---GIFSINMNTPDRI-NINGGKMRKAASLAKLFILVEAFRQSQ +DGKLSLEKQIHIEKEHLAYGAGVITYLTGSRFTYRNLIELMIIVSDNTAANLMMDVV-DR +HNVNKLAKQIGCTKTVINRKFMDVTAQ-QVGKENYTSANDVIKLLQLISKNNILTDHSRT +QIMNILSDQQL-NHKLPSNIQHHITFYHKTGELP-GVEHDAGIVVNKQK-LVEVAVLSEG +W-VEAGTAQSYISEISKVLIQY- +>[subseq from] Serine hydrolase n=1 Tax=Jiangella sp. NEAU-YY265 TaxID=2293569 RepID=A0A418KHX7_9ACTN +----EGELRDAFAAAGVSGYLHAVDVSSGTEV-GLEPDAPVVTASVFKVPVLVELCRQFA +TGERAPTDRLRVPAGSRTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR +ECVNAAMAALGLPGTVLEEDCAGLFRVLDAGTTNRSTPRETTTLLRRVWTADGLPEQACA +EIRRIMGLQVW-PHRLTSGFPDDVRVSGKTGTLSH-VRNEVGVVEYPDGATFAVAVFLRL +PGAENPAADRVIGTAARIAVDH- +>[subseq from] serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=UPI000D95760B +------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE +EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-CM +DKINETIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ +MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG +IPNS-VYGTVTLAKSGKMTWD-- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. UW69 TaxID=368493 RepID=UPI000E0F1C55 +---LSQRWVELAQQTDLQASAYMLILDDGRFA-AMQAERPMPAASSIKTPILLAVLELLD +QGTLQWNEPLTLTQELVGGGAGWMASRPLGSFPTYEVATEMIRVSDNSATNLMIARAGGM +EQINARFQELDLPATVVNNWLPDLDGT------NTTSARDLSRAIALVDSGEVLGPRSRD +LFREVMGTSVT-NTLLPTGLMRGYRVYNKTGDIGL-AYADAGLIELPDGRRAVAGFLVKG +PFN-DPRSTELIRQLSAAMA--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. ZEA17I TaxID=2202516 RepID=A0A2V2PQX2_9ACTN +-----RTVRSLFDDAGVRGWLHVAELERSARV-VLDPDEPVPMGSVYKIALMAAFCRLAD +AGRLDPCHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLREV-GT +DAVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDRAASPASCA +FMRAAMGTQPW-AHRLASGFPDDVAVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] serine hydrolase n=1 Tax=Emergencia sp. 1XD21-10 TaxID=2304569 RepID=UPI001379E7D8 +-----EQILNELSQMEGKVGFYYHNLVTGETY-GYREKEPFLPASVVKLPLMAAILLLRS +RGEADFREEILIHQDQKVPGCGAVQHMTGEVLDMETLGKLMITISDNTATNALLRHY-TV +PKIREAFLELGLIGTQFNRELWDLERE-ARGINNYFVPEEIGILLEKIYHKTLVNEESSI +WLDDIMRQQQI-NHKMGGHLIMDYPMAHKTGDEED-KAHDVGIVYAK--QPFVVCFASNE +VD--VPMYEDFIRRTTKALVE-- +>[subseq from] Uncharacterized protein n=1 Tax=candidate division WWE3 bacterium RIFCSPLOWO2_01_FULL_37_15 TaxID=1802622 RepID=A0A1F4UTC5_9BACT +--NLNKQIDIQLKKLGGDVTLRVKFLNTKEEI-KVNQDFQFWAASVIKIPIACEFFRQVN +EGKINPETKTKIKAENRVEGSGVFKLLNKDDFTYLDLVTLMLDISDNAGTNEIVDII-GW +ENVEKYMHQLGLLNTTFRHKMMI--K--AGRGPNFTTAQDITILLEKLYNNEI---PGAA +QILAILKQQQD-RRRIPLLLPNDIEIANKTGSLEK-AVHDAGIIYSKNP---FIFVFLSD +DQEDKILTNEVLSGCAKLCFD-- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter malorum TaxID=178901 RepID=A0A149UMG1_9PROT +----AQIMTKTVSKQPGHFAVYAARSGEAPDV-CLNCDDLINAASTMKLFVLDTAYEAFT +KGTLHPEDTIVVHNHSLVGGSFALYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV +LPIRSVVKAQGLNGIVFGRMIEDFDAN-DQGIRNQVSARGLGDFLQKLDSGQIVGKAQSQ +SMIQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVD-GVRNDAAIVTLPDGKRYILVVLTSG +LP-DEQAGIRVLNTLSHQAYEYf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces cavourensis TaxID=67258 RepID=UPI000E0CF304 +----ERTIRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD +AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GS +DAVDGMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDEAASPESCA +FMRAAMGTQPW-THRLASGFPDDATVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0004906DB1 +-----RTVRSLFDDAGVRGWLHVAELERSARV-VLDPDEPVPMGSVYKIALMAAFCRLAD +AGRLDPCHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLREV-GT +DAVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDRAASPASCA +FMRAAMGTQPW-AHRLASGFPDDVAVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10) TaxID=700598 RepID=G8TCL6_NIAKG +-hRLQQKIEETVKGLNGDIGVYVKNLRTGKVA-AFNSDTIFPTASMVKVTILIGIEDKIE +KGELEYHQQLEYRDSLYYAGEDILGSFKNGEIGLHKVMMLSLTTSDNTASLWLQSLAGNG +TRINQILDSLGLVNMRVNSRTPGREANRNQYGWAQTTPREMGTLMEKIYNGEVISKKASE +KMIRLLGRNYN-DEQAIAEIPPYIFVASKNGCVN-ASRSEILLVMAPHG-PYIFSVETKN +LKDNSNEAWELTRKLSTLCWNYf +>[subseq from] Serine hydrolase n=1 Tax=Pedobacter sp. Leaf176 TaxID=1736286 RepID=A0A0Q5NCF2_9SPHI +-kKLQLKLNELVKGFNGDVGIYVKNLKTGKTA-SVNADTIFPTASMIKVPITCGIFSKIE +KGELDYHSELMYCDSLLYAGEDILGSFKDSEIALNKVLMLMITTSDNTASLWAQLLAGTG +TAINEVMAKNGLKDTRVNSRIAGRKDNQKKYGWGQTTPREMATLLTLIRDGKMINPAASE +RIYRNLIRIFW-DTEALSQIPPTVQVASKSGAVD-AARSEVLLVNAPHGD-YVFCITTKN +QKDTSNEGWTMIRKLSNLLWSYy +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CNZ288 TaxID=2512147 RepID=A0A4Q8CWP7_9ACTN +hrTARSRIRRAFTEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE +HGRVDLTAAVDIPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI +EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA +DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIAVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAARLAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Symbiobacterium thermophilum (strain T / IAM 14863) TaxID=292459 RepID=Q67QZ3_SYMTH +------TLNALVAGFSGTMGVWARSLQTDEVIqVGASDDTFPSASTIKLAIFYEVMRQAG +EGRLDLSEPRELRTEDKVPGCGVLRDLSPGILPLRDLATLMMIISDNTASNMCIDAV-GI +ESVNRSMDELGLTGLRLRWKFF---GAPAGQPVNAAVPSQLGRLMDMIVRRQVLTPEACD +EMLRVMKQVQSAARYLPGGSPEGPVIAAKFGSIT-GCRHEVGAVWKGGR-GFVFSVMTKD +CKERRVEDNEGVLAVGRAVA--- +>[subseq from] serine hydrolase n=1 Tax=Acetobacter persici TaxID=1076596 RepID=UPI000A36086B +---LAQRMAETVADQPGHYAVYAARSGQAPDV-CVNCDDLINAASTIKLFVLDAAYAAFA +KGTLHPDDTLTVHNRSLVGKGHFAYAQAGKAVPVSELLRVMIQYSSNLATNLMIEKL-GV +LPIRSVVNAQGLNGIVFGRMIEDFDAD-AQGIHNRVSARGLGSFLQKLNNGQIVGKTQSQ +SMIGIMLGQKF-NDIIPPGLPAGTPVAHKTGWVN-GVRNDAAIVTLPDGRQYILVVLTSG +LP-DEQAGIKVLNTLSHQAYLYf +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0011DE38F6 +-qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDTAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Beta-lactamase class A-like protein n=6 Tax=Patescibacteria group TaxID=1783273 RepID=A0A0G1CWY3_9BACT +---LKKKIIEAIGTTIPEYSVMVKDLKNDFSI-DMNANTIFTGASVNKLPILGTLYYLAQ +KGDIDLDRQITIQPEDIQDTGQIRYDQPGTMYSVKTLSRLMMQKSDNTAAYILGRQVIGI +PKIQQLITSWGMTQTDMEN--------------NKTSNTDIALLMEKIYREKVANKALTL +EMLSFLKDGTI-EDRIPALLPKETVVYHKTGNGV-GFLHDVGIVVGPKT-TYYIGMFTSG +VP-DEAEAVRILATISRIVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Anaerocolumna aminovalerica TaxID=1527 RepID=A0A1I5GN18_9FIRM +--TLEERIKAELASYNGTMGIYVNDF-QGNKV-EINIDKEFETASTVKTYILGTLFDEVE +KGNKNLSDKLIYTQENEIEGSGILRSLDYGVLTVKNVATLMIIVSDNIGTNMMIDYL-GI +DTINAFMQSYGFTHTKLHNKIN---FD-IYDKLGTTTPRDYGKIFEMICKEELISPEASR +QMLEIFKKQHY-NSMLTKSFPQYIYVASKSGSMD-ACRNDGGIVSTPYGK-YVIVLFNKN +FTDPEHQATVFGSKVSRLIFDQy +>[subseq from] serine hydrolase n=1 Tax=Dyadobacter sp. 3J3 TaxID=2606600 RepID=UPI00135C2CFA +-kKLTEKLEKALAGFKGSAGVYVRNLKTDKFA-SVHSDTIFPTASMVKIPIMIGVFDKIN +KGELQFDQLLTYRDS-LKYDDGITGSFRDSTIPLPKVIHLMISLSDNTGSLWLQALAGGG +AAINQWMETNGFVNTRVNSRTPGRKQNQAIYGWGQTSPREMAELMVMIRQGKVISPSASE +RMYRYLGMQFW-DGEALSQIPPFIKTGAKSGAVNQ-AKSEVVMVHAPHGD-YVFCITTKN +QQQRDNEGYDMIRKVSEIIWNHf +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Saccharibacteria bacterium QS_5_54_17 TaxID=1919228 RepID=A0A2T2QWJ4_9BACT +-qEIRQELNEMLESADGSWSVYVRSFDQEEAAfEYGRDKVFYAASINKLPIALYALSQVE +EGKIGLSDKLEVTEEVKRPGTGILRLHEGLDVTVEDALTLMMAVSDNTAAKLMVRKA-GP +ENINQYLEASGLADTRLEVLPEGKFS------YGYTTAKESAQLLRGIHNAEYVSPEASR +KLLGMMGRNHF-SHGVRRYLPKDLKIANKEGSLED-NRHEIAAVMAE--RPYAICVFADE +LA--------------------- +>[subseq from] Serine hydrolase n=2 Tax=Cyanobacteria TaxID=1117 RepID=A0A1Z9Q274_9CYAN +----SGKWKQLAAQQDLKASAYMLILDDGRYA-AMNPERPMPAASAIKTPVLLAALELID +SGELHWNEPLTLTKELVGGGAGWMAKPVGSRFPTHETATEMIRISDNSATNLMIERAGGM +KXVNARFQALGLPSTEINNWLPDLDGT------NTTSARDLSRSIALVDTGESLSLRTRD +LFRDVMATSVT-NTLLPTGLLQGYRIYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVQG +PFND-PRSTNLIRAMASAM---- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. UBA8071 TaxID=2055764 RepID=A0A3D3TWY7_9SYNE +--------ELAAQQSDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD +QGTLQWNEPLTLTEELVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLMIARAGGM +DAINARFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD +LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG +PFN-DPRSTELIRQLAAAMA--- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. RS344 TaxID=2024886 RepID=A0A2E7LV02_9SYNE +--------ELAAQQSDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD +QGTLQWNEPLTLTEELVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLMIARAGGM +DAINARFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD +LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG +PFN-DPRSTELIRQLAAAMA--- +>[subseq from] Serine hydrolase n=1 Tax=Pedobacter sp. Hv1 TaxID=1740090 RepID=A0A0Q0VLF6_9SPHI +--KLTKMLTELTKGFNGDVGIYVKSLKTGKVA-SLNADSIFPTASMVKVPITCGIFNKIE +KGELDYHAQLTYKDSLLYAGEDILGSFKSGEIWLSKVLMLMITTSDNTASLWSQSLAGTG +TAINELMEQNGLKYTRVNSRTPGRQANQKQYGWGQTTPREMATLLTLIRDGKMINPAASE +RIYRNLIRIYF-DHEALSQIPPYIQAASKSGAVN-AARSEVVLVNAPHGD-YVFCIATNN +QKQSNNEGYVLIRKLSKMLWQYf +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. UW86 TaxID=368491 RepID=UPI000E0EEF48 +--------ELAAQQSDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD +QGTLQWNEPLTLTKELVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLIIARAGGM +DAINARFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD +LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG +PFN-DPRSTELIRRLAAAMA--- +>[subseq from] Uncharacterized protein n=1 Tax=Deinococcus koreensis TaxID=2054903 RepID=A0A2K3UYZ9_9DEIO +--------------------FCVHELGTGMIR-AQRADEVVPTASTYKLPLLLHIALLVE +EGALSWAQPFTLEDRHKSWGSGVLRDSVGLTFPLRDLCHLMTALSDNTATDLLLDTL-GL +DGVNRRLAGLGFEQTRLLPQHAAPGAGRPPLAVGVTTPAEMARLLRGIVLHELCSSASSS +VILGMLGAQHD-RSMIPRFLQPDWIYSGKTGSNED-LRADVGIVTDPQGRSFVLALYCQH +PT--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A0D6IR82_ALCXX +-qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Beta-lactamase n=1 Tax=Sphaerobacter thermophilus (strain DSM 20745 / S 6022) TaxID=479434 RepID=D1CA76_SPHTD +--SLAERIDPLVAEVPAEIGIVVALPDGTRLY-EYQPDRLFEAASLYKLGIMVELYRQRE +AGWISFDETITLLPGYYEEGPDVYGEAIGTAVPIDDLLWAMIAASSNVASHALLDRI-GN +EAVNATMAGLGLVQTEIR------------------------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. MYb64 TaxID=1848691 RepID=A0A2S8ZU09_9MICO +------SIAEIFADADAEGFLHAREIGTGPEV-DSGADEPVVLASVFKILVLTAYVRAVA +AGTLDPTERTTVTARYRIGGIGTAGFSDDVQASWRDLAQNMMTMSDNAATDVLYHRL-GG +DAVDRVIADLGLRNTRLIGCCEDLFAALDPARTSASTPRDVTTLLNALWTDTAAPAEACA +QARAIMAQQIW-PHRLTSGFPNGVTLAAKTGTLPR-WRNEAGVVTYPDGRQYAVAVFTRA +HTLD-ERLPRVDASIGR------ +>[subseq from] Serine hydrolase n=1 Tax=Lactobacillus paraplantarum TaxID=60520 RepID=A0A370ACM7_9LACO +---VSELVEQTMQDVAGRTSIAVMPLTGSQTV--IVNNGAQRAGSLITLFILVTAYDQVH +QNNWQMQDRYTLRAEDKVGGTGTLHTLPAGSLTYAEIAKRMITDSDNTAANIMLDRVGGV +SAINSEVAQLDLKDTKMARRLMDTA-ALKAGRDNYTSVRDVATILQRLANYRLISKRVDQ +TMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVKNRQGA-FIMTVMAAD +GEREA--QTTALN---------- +>[subseq from] Beta-lactamase class A n=1 Tax=Desulfotomaculum arcticum DSM 17038 TaxID=1121424 RepID=A0A1I2ZK77_9FIRM +---LDQSVSEYLVAQEGTYGLYFIDLKSGEKF-GYNQYTSFHAASTFKLPMNLYLYTQAE +KEKINLAQKLTYQSRHAEGGTGILKNYPPGKYTIKQLATYSIVNSDNIATNILLERL-DR +KKVKSYMRDLGGKVVE--------------DDNNVTCPHDLALYMQKTIEFYRTGSPEAK +MLTENLFAAEF-KDRIPAAVPPGVKVANKIGNWPTGTYNDVAYVEHPVR-PYILAVTCSG +TP-GYGSAVPVIRQVSKMIYEY- +>[subseq from] Serine hydrolase n=1 Tax=Lachnoclostridium sp. TaxID=2028282 RepID=A0A352P9A9_9FIRM +--TLEKRIEAEIMSYDGKMGIYLDDF-HGNVI-AIHADEAFETASSIKAYILACLFDELE +KGNKSLEDIIEYKEEHAVDGSGVLAAEPGVKLRVKDAATFMIIVSDNIATNMMIDYL-GL +EKINQCIKTLGCKDTVLHNSIH-FER---YDRLGTSTPRDYASIFIRLAKGELISPRADE +MMLGILKKQHY-NSMITKDFPPFISVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE +FSDAAHPATVYGARVSRMILDQf +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora flava TaxID=95161 RepID=A0A1I6RF85_9PSEU +---TEQRIREVLADAGAQGWVHAVRLGGGHEL-GSGADDLVVTASVYKLPLLVALARAFD +AGTLDPRETIRLDPTACTPPTGVAIFQDPVRLSWRDLAASMVSVSDNAAADVILGAI-GL +DAVTETLADLGLERTRVVGGTADANAAYDPSYASATTPREMTRLMELIWADAVASPQQCA +FVRRLLGQQAW-MHRVRAGFPRGVQVSGKTGTIG-AVRNEVSVVEFDGEAPVAVAVFTLA +ARADLPRVDEAIAECARLAV--- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter cerevisiae TaxID=178900 RepID=A0A149V9B1_9PROT +---LAQIMAKTVTKQPGHFAVYAARSGQAPDV-CLNCDDLINAASTIKLFVLDAAYEAFT +KSTLRPEDTMTVHNHSLVGGSFALYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV +LPIRSAVKAQGLNGIVFGRMIEDFDAN-DQGIRNRVSARGLGDFLQKLDSGQIVGKAQSQ +SMIQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVD-GVRNDAAIVTLPDGKRYILVVLTSD +LP-DEQAGIKVLNTLSHEAYTYf +>[subseq from] Beta-lactamase class A n=1 Tax=Asanoa ishikariensis TaxID=137265 RepID=A0A1H3TB82_9ACTN +-----DRIAGIFAAVGVDAQLHAVDVDRGTEL-SVRADEPVVLASIFKILLVLEFARQAA +AGQLDPTERVVVRAEDRLGGWGTSGCADDAELSLRDLAYFAMAFTDNTAADLLLRRV-GP +DVLPLLTAELGLTTTRITGGPRELLEVFDPDKTTSSTPREVTRLLELIWRDEAGPPAATA +MVRALMGRQIF-WTRIASGFPPGVRVSAKTGTLP-GLHMEAGVVEYPDGGRYALAIFARA +HQLDFRRVDLAMGEAARTAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Nocardia pseudobrasiliensis TaxID=45979 RepID=A0A370HZV6_9NOCA +--------------AGVQGWLHARCLDCGAET-GWRADEPVVLSSVVKVPLVLELARQIA +AGQLDPTDRVRATAADRLGGPGTSGCRDDVEYSLRDAAYLALSVSDNTAADLLFDRV-GL +DNVRSRVHELGLTRTRVVGALRDLLIIMDPGRTSASTPREMTRLLELIARDEAGPPAACA +WLRELMGAQLN-QARLGSAFGDEVTLWSKTGTLP-GVRNEIGVVRSPDGTRCAVAVFTRA +AVDRAPRVDRAIGAAARAAIE-- +>[subseq from] Beta-lactamase regulatory protein BlaB n=2 Tax=Microbacterium azadirachtae TaxID=582680 RepID=A0A0F0LMY5_9MICO +---MTTSIAEIFADADAEGFLHAREIGVGPEV-DSGADEPVVLASVFKILVLTAYVRAVS +AGTLDPTERTTVTARYRIGGIGTAGFSDDVQASWRDLAQNMMTMSDNAATDVLYHRL-GG +DAVDRVIADLGLRNTRLVGCCEDLFAALDPARTSASTPRDVTTLLNALWTDTAAPAEACA +QARAIMAQQIW-PHRLTSGFPNGVTLAAKTGTLPR-WRNEAGVVTYPDGRRYAVAVFTRA +HTLD-ERLPRVDASIGR------ +>[subseq from] serine hydrolase n=1 Tax=Streptomyces agglomeratus TaxID=285458 RepID=UPI0008543D93 +-----ERIREVFAGAGAEGLLHAVPVGTEEEV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFLAISVSDNSAADLLLARV-GL +DTVRLLARELGLGGTRIVGGPRDVLEVLDPLRTNASTPREITRLLRLVWRDEAGPPEACA +HVRDLMARQAF-RHRLVSGFPDEATVAAKTGTLP-GLHMEAGVVRYPDGGRYAVSVFART +RDASRPVVDAAIGATARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Flavihumibacter sp. SB-02 TaxID=2676868 RepID=UPI0012FC7240 +------------QGFKGDIGFYIKNLKTGKVA-SYNADTVFPTASIVKVPILVGILDKLE +KGELNYHDQLTYADSLYYAGVDILGSFKDGEIELSKVIMLMCTTSDNTASLWLQQLAGTG +TRINQLMDELRLPNTKVNSRTPGREEIRKQYGWGQTTPAEMATLFEKMLQREVINGHASD +KMMRILGRNYW-DEEGLSKIPPGVFVASKNGAVD-ASRSEVMYVNGHK-TPYIFAVFTKN +NEEPTNEAWELTRRMSDFVWTYf +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. N5 TaxID=2575515 RepID=UPI000E0E1FAA +--------ELAAQQSDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD +QGTLQWNEPLTLTKELVGGGAGWMATRPLGSFPTHEVATEMIRVSDNSATNLMIARAGGM +DAINALFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD +LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG +PFN-DPRSTELIRRLAAAMA--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces puniciscabiei TaxID=164348 RepID=A0A1D7Y4Q3_9ACTN +------RIRAAFAEAGVTGRLHALDIDSGAQI-DVGADQPVCTASVHKLCLLVTLHELAA +TAHLDLGEQIDCEPAGRTAGPTGLAAMLDPVMSLRDVAYLMMAVSDNASADLLLRRV-GL +DAVNRTTARLGLTRTHAVHTFGELFAALDPDRTNRSVPRDMTRLLGAVWRDEACAPEHGA +SIRRLLGLQVW-PHRLASGFPDDVHVAGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRT +ANATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. C105KSO15 TaxID=1776047 RepID=UPI0007405DC1 +--TLEKRIEAEIKSYDGKMGIYLDDF-HGNVI-SIHADEAFETASSIKTYILACLFDEVE +KGNKSLEDIIEYKEEHAVDGSGVLAAEPGAKLRVKDAATFMIIVSDNIATNMMIDYL-GL +EKINQCIKALGCRDSVLHNPIH-FER---YDRLGTSTPGDYASIFIRLAKGELISPRADE +MMLEILKKQHY-NSMITKDFPPFISVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE +FSDAAHPATVFGARVSRMILDQf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNQ-525 TaxID=418855 RepID=UPI00056309EF +hrTARSRIRRAFTEAGVTGFLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE +HGRVDLTAAVDIPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI +EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA +DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIAVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Flectobacillus major TaxID=103 RepID=UPI000414306D +--VLETKLQNLVKGFHGDVGIYVRHLKKNKMA-SIQPDSIFPTASMIKVPITIGLFNKIE +QGLLDYHAVLTFRDSLLYAGDDILGSFKDGEIALAKVAMLMITTSDNTASLWCQAMA-TG +TGINEWLDSNGFKDTRVNSRTQGREPARKKYGWGQTTPREMAELFVKIREGKVISPAASE +RIYRNLIRIYW-DGEALSQIPPTVQVASKQGAVNQ-SRSEVLLVNAPSGD-YVVAVITKN +QKERTNEGYVFLRAISKTVWEHf +>[subseq from] Class A beta-lactamase n=1 Tax=Megasphaera sp. BV3C16-1 TaxID=1111454 RepID=U7UIN5_9FIRM +---------------AGELAVYCRRLGGGEPF--LLRDRPMAAASLIKIPIMIEAFRQER +AGRISFSARWPVRAA--VPGGSFYTLPINTPVTTAVLIEHMIVESDNTCANMLLDIL-GM +AAVNDCIDGLGLKGTRLRRKMMDFTAA-AAGRENVTTPGDMGRLMTLLAEGRCLGRRADA +AMCGILSRQED-NCVIPAQMVRSLRIDHKTGELA-GVYHDCGILYAPQGK-LILCLMADG +IKNEA-QAIYDMSYLARA----- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. CPC100 TaxID=2024879 RepID=A0A2D5RB38_9SYNE +---LSKRWQTLAAEQDLDVSAFMLVLDDGRYA-QLEPDTELPAASSIKTPILLVTLEELD +AGRLSWNEPLQLSQTVVGGGAGWMAKPLGTRFPTHEVATEMIRVSDNTATNLLIERLGGR +EILNARFNALGLSATKVNDWLPDLKGT------NSTSARDLARSIALVDTGEALSIRSRD +LFREVMGTSIT-NTLLPRGLLRGYKVFNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG +PFND-PRSTELIRKLAAAM---- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CS090A TaxID=2162710 RepID=A0A2T7KKZ0_9ACTN +---VERTIRSLFDDAGVRGWLHVADLHRPARV-VVDPDEQVPMGSVYKVALMAAFCRLAD +EGLVDPRHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA +EAVDGMCAELGLPHTRIHGGVVGTFDVYDPAYKASSTPAETARLLRAIWTDEAASPESCS +FMRAAMLTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSVYTAVVFTQA +ARADLPRADAVIGAAARAAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. MED-G134 TaxID=2518987 RepID=A0A520LHE1_9SYNE +----SQRWVELAQQTDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD +QGTLQWNEPLMLTEELVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLMIARAGGM +DAVNARFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD +LFREVMGTSVT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG +PFN-DPRSTELIRQLAAAMA--- +>[subseq from] Serine hydrolase n=2 Tax=Actinosynnema sp. ALI-1.44 TaxID=1933779 RepID=A0A1V2PP99_9PSEU +-------------------------TPPGREV-DVDADEPVVMASVYKLVLLVALCRRFE +DGLLDPQSTVRVNPASCTPPTGISTFLDPITMSWRDLAASMMTVSDNAAADVILGEV-GL +DAVQRLLVEEDLTGTRIIGGTADVAAAYNPVYTSATTPRDMTRLLSLIWSDAVVSAEQCA +FIRRLMGMQVW-SHRIRAGFPGDVRVSGKTGTIG-AVRNEIAVVEYAGELPIAVAVFTFA +ARADLPAVDAAIAEAARLAV--- +>[subseq from] Serine hydrolase n=1 Tax=Caulobacter sp. FWC2 TaxID=69664 RepID=A0A2G5QS66_9CAUL +-kNLQKRIEAIAARAPAVLGVAVEDLGTRQLW-AFNGDRRFALGGAARIPILAAVMAETE +AGRLPLDEIVTVRDVDLSPPSAVADAWPGRNWSIAELETLA-RQGDNTALDLLIKRVGGP +GAVNGWLDVKRIEHVSVDRYRRQIATERATDPRDTATPIGLLRLMEAFTNRELFYKPDPA +RLLG---RD---AGYLAKALPAGARIIQLAGAARQPTNHAAAFVELKDGRRIAFVVFLTA +STADAAQREAIITDVGEAVLKEf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. YC504 TaxID=1775132 RepID=UPI0013EC1488 +----EQRIREVFAEAGAEGVLHAVPVGDTAEV-AVGADEPVVIASIFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCVDDIELSLRDLAYFALSVSDNSAADLLLDRV-GL +DTVQLLAKELGLTRTRIVGGPREVLEVLDPQRTNSATPREITWLLRLVWRDEAGPPQACA +QVRELMARQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGGRYAVSVFART +REASRTAVDSAIGATARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Cupriavidus sp. USMAHM13 TaxID=1389192 RepID=UPI0008A6B490 +--RVEAGLAPLLAATPARVALSLR-LRDGSIVlERAASCAMPSASLVKVPILLAMLEQVG +QDRLCLAQEMSLAGIERVGGTGILAQLPSVRLTLAELARLMIVLSDNVATNALITLL-GF +DAVNGWCERAGLAQTRLQRRMMDAAAR-AAGRDNFTSAGDTAAALGWLLRGDTLPAPLRA +FGLALLADQRE-RAHFGAALPAAARLANKTGQLP-GLRHDAGILTVGDQ-SVVLAVLADG +FTDPRTARE-------------- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus paraplantarum TaxID=60520 RepID=UPI000CB39FD0 +---VSELVEQTMQDVAGRTSIAVMPLTGSQTV--IVNNGAQRAGSLITLFILVTAYDQVH +QNNWQMQDRYTLRAEDKVGGTGTLHTLPAGSLTYAEIAKRMITDSDNTAANIMLDRVGGV +SAINSEVAQLDLKDTTMARRLMDTA-ALKAGRDNYTSVRDVATILQRLANYRLISKRVDQ +AMLTILKANTD-HSKLVKNLPKRATIYNKTGDYQYGVQNDAAIVKNRQGT-FIMTVMAAD +GEREA--QTTALN---------- +>[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=UPI00138F163E +------------------------------------------------------------ +----------------------------------------------------------GE +PRLQALADALGVPRAELDATLEQVFEDYYARGLNSATLPAYGRLLARLAGGELLSPRSTD +LLLGHMRAINTGSRRIQAGLPPDADFAQKTGTQLQ-RACNVGLLDPGGRDGATVVVACAE +RFGELEQAEQAFQALGRALAD-- +>[subseq from] Uncharacterized protein n=1 Tax=Vagococcus fessus TaxID=120370 RepID=A0A430A7S2_9ENTE +--EVRSALDTQLKNVYGTNSYYFQDISVQQAF-ETN-DQKQLAAGMINLYIMQMLFDKVE +QGKMELSGSYKLTSKDKTSGTGVLKDMSDGTLTNEKLVEYMLVDSDNTATNVLINRLGGL +GEIEKFIQSKGYSNTHINRKMADMG-AISQGKENYTSVKDTGNLLSKLYKHDLVSKEMDD +KMLAILSKTKD-KAKLRKDLPKDVTVYSNSGQFSYGVINDAMIVKTKDKT-FVLVVLMQN +GDQY------------------- +>[subseq from] serine hydrolase n=1 Tax=Heliobacterium undosum TaxID=121734 RepID=UPI001371A16D +---LKQKIQGYLNTRPGQVNLYVQDLTSGAKM-DIAGDEIHRTASTHKVPTVMYLYSLAA +QGKVDLDAKLTYTSQYYRQGTGILQTKPYGGYTLRELGRLSIVYSDNVAWVMLLDYL-GR +ENVNNYMRSLGANVTGSDANGYF-----------ITTPCDMGKYLGALLVFKDAYPQLGG +EIFSAMQNTIF-NERIPAKLPNGTVVAHKIGSLND-SIHDMGIVFANNR-PYIISLYSKN +AW--EAASNETLAQVSKMVYDH- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Shapirobacteria bacterium CG03_land_8_20_14_0_80_39_12 TaxID=1974879 RepID=A0A2M7BBR2_9BACT +----RQAVEQIIEPLRGTYGIYFRDLEKGDAF-SINSLEKMTAASLIKMPTLLTLYREAD +AGRINLDTIYKLQAADRRGGAGSLIGRPEGSVSYREMAKLMGEQSDNTAFNIVANKILGG +EKIQNTINLLGMRQTSFN--------------DNITTPEDMGLLFRKLLQEKVVTDKSRD +EILSFITNTIW-ETRIPAGIPKGIKVSHKIGSDI-GVVSDAGIVFAK--KPFILVIMSQN +ANE--IEAGKALPEIAKKIYEMw +>[subseq from] serine hydrolase n=1 Tax=Asanoa ishikariensis TaxID=137265 RepID=UPI000B86C0D8 +-----DRIAGIFAAVGVDAQLHAVDVDRGTEL-SVRADEPVVLASIFKILLVLEFARQAA +AGQLDPTERVVVRAEDRLGGWGTSGCADDAELSLRDLAYFAMAFTDNTAADLLLRRV-GP +DVLPLLTAELGLTTTRITGGPRELLEVFDPDKTTSSTPREVTRLLELIWRDEAGPPAATA +MVRALMGRQIF-WTRIASGFPPGVRVSAKTGTLP-GLHMEAGVVEYPDGGRYALAIFARA +HQLDFRRVDLAMGEAARTAV--- +>[subseq from] serine hydrolase n=1 Tax=Runella sp. CRIBMP TaxID=2683261 RepID=UPI0014120C83 +-kKLTTQLQEAIKGFRGDVGVYVRNLKTNKIV-EINADTLFPTASMIKVPIQCGLFDKIA +KGELRYNAILTYKDSLHYDDGIVGSLKDGAKIPLSEVVMLMETVSDNTGSLWCQALAGGG +KSINEWLDKNGFTATRVNSRTPGREANRTRYGWGQTSPREMAELFAMIRQGRAISPDASD +RMYRNLTRQYWDGEGL-SQLPPDIKTASKNGAVNR-SRSEAVLVHAPHGE-YVYCVITKN +NLTSQNEGYVLLRKISKLLWNYy +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536JVS1_9CHLR +---------AALASLPGEAGAFASDPDGRAIF-CEREDDLFPSASVIKLPLVMTLYADAA +RRLVDLDELVSVG--DRVDGTGVLRHVPDVELSLRDLATLAIIVSDNTATNRLIERI-GV +DRVGERMREWGCPLSRLSRKMYDFEAA-KRGSENVMTARETVSLLLRLQRGECEDRATSD +AVVVLLEQCQD-RTMLLRYVPDTTNAPHKTGTLDE-SRNDAAIV--PGERPVTVAAFTRK +LRDT------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. MJM8645 TaxID=1120523 RepID=UPI000AD113A2 +--TARARIAAAFADAGVSGRLHVRDLDTGTEI-ALDADTPVSTSSVHKLCLLVTLFREAA +AGRIDLTRQVDVPAAGRTSGTGLAAMLDAARLSLRDLAYLTVAVSDNAAADVLWDEI-GL +DTVNRTMADLGLTRTVAVHKLRDLIAVLDPTFTNRSTARDMTTLLAALWHGDACPGEHGA +ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAIFTRA +AATTLPAADAAIGTTARLAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Dyadobacter koreensis TaxID=408657 RepID=A0A1H6U0N9_9BACT +-qKLVSKLEEAMKGFRGNAGIYVKHLKNNRIA-SVNSDSVFPTASMVKIPIMVGIFEKIR +QGGLKFDQVLTYRDSLKYDDGVVGSFKDSTKIPMPKVIHLMISESDNTGSLWLQALAGGG +EAINQWLETNGFENTRVNSRTPNRKQAQATYGWGQTTPKEMAKLMLMIREGKVISPDVSE +RMYRYLGMQFW-DGEALSQIPSNVKTSAKSGAVNQ-AKSEVVMVHAPHGD-YVFCITTKN +QLERSNEGYELIRKVSEIIWNHf +>[subseq from] Uncharacterized protein n=1 Tax=Selenomonas sputigena (strain ATCC 35185 / DSM 20758 / VPI D19B-28) TaxID=546271 RepID=C9LY50_SELS3 +-eALRADFSAILAPKSPDCSVFLLRPREEKEP-LLYQSHAMQPASMIKLFILAYAMQQAK +DGTLSLAEPLSITEANIVGGAGQLNWYDRGKLTIEQLLERMITDSDNTATNILIDRL-GI +ENIDGYIRQKGYADTRLQHKMMLSNQG----RPNLSSVKDIGTLLSLIYRGECVDYEHDK +KMLQILSRQKD-KDCLPSALP-AFLVANKTGEIT-GVYADGGIAWSDAGD-LILVVMDEN +CR-DRQETIALFQRIAQRA---- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007C12C24 +---VTDLIEQATNGLAGQTSVAVMPLAGSQSV--VVNNHAQRAGSLITLFIMVTAYDQVQ +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTRMARRLMDTA-ALRAGHDNDTSVRDVATVLKRLANRRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVRNRQGT-FIMTMMAAS +GER--TAQTSAMNDLGQVLYR-- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0009706CE3 +-qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA +NGRYALEQPLALPAGDRAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIELL-GF +DEINQWNQRAGLPASRLQRRMMDAAA-REAGRDNFTSAEDATASLCWMLRDGALPAALRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADRS-VVLAVLAVG +FTLQGGEGAALLGQIARAV---- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. TSRI0281 TaxID=1718998 RepID=A0A1Q4Z900_9ACTN +--TAEARIRAAFDEAGVEGFFLAREIDGDRTI-GVSADEPVVLASVFKIPVALAYAREAA +AGRLERTERLAVDARYRDGGIGTSGCADPIEMSLRDLVHLMLTMSDNAATDVVLARV-GL +DTVNGLLRELGLEHTHLIGGCLELISVCVPELTTRSTARETAELLARIWRDEAGSAVACA +EVRAVMAQQIW-PHRLGSGFDDSYRLAAKTGTLP-GWRNEAGVIEHPGGGRWAVAVFTRS +DTPDNPRADRVIGQVARLAVDE- +>[subseq from] Beta-lactamase class A n=1 Tax=Thermoanaerobacterium thermosaccharolyticum M0795 TaxID=698948 RepID=L0IHH2_THETR +-qELKNNIETLLSQHPGKYGVYFIDLNSGQTF-NINGYDSFVAASTYKVPLNFYLYTLIT +EGKIDPNMEVQYTSQDYESGSGSIQYDPVGTYTIRELSRRSIEESDNIASNMIMRVV-GY +DNYLNFMKSMGADVIPY--------------TSNVTSPRDLSLYMENLLNYANAHSSTAG +ELLNYLENTIY-NDRISYPLPSNITVAHKIGNLSD-VVNDTAIVFYPSR-PYILTVMGNN +VDSDNSDAYTVIREISKMVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536LXG5_9CHLR +---LEGELLRIGSTYSGKWTYALTDMSSGQKI-GHRQDDVMPTASLIKVPVLTALYRAVH +EGRLRLTDRIRYGDEHRCLGSGVLSRLTPGVMTVRDAAVLMIIISDNSATNIVIDLV-GL +DQVNETMRCFGLGRTTIFQRLGDTKAGLDARKMSVSTAGEMTRLLELIARHEAVPPEASE +DMLRIMRRQDY-RHELSRLLPTENWVAEKGGSFLNGIRTSGAIFNGSRG-KFVMSVFCEG +GTGP------------------- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. N26 TaxID=2575513 RepID=UPI000E0EB2D9 +--------ELAAQQSDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD +QGTLQWNEPLTLTEKLVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLMIARAGGM +DAINARFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD +LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG +PFN-DPRSTELIRQLAAAMA--- +>[subseq from] serine hydrolase n=1 Tax=Paenibacillus sp. 7884-2 TaxID=2022552 RepID=UPI000BA733AF +---------------------------AEGTI-QFNANTPRKAASVVKLFILAEVLQQIE +AGRIQREQLISIKPEAMVEGAGVINYLTKHNYSYQNLLELMIIVSDNTASNILLDMI-GI +DRINHSIKKLGCQDTIIKRKFMDQEA-QASGNENITTAADIVHLLKLFSSDNGYSKNLRQ +EVRRLLKNQQF-NNKLAAYQMCKLNIYHKTGELP-GVEHDVAIMESTGRK-LEVAVLTEG +WEN-NGIAQHFIAEVGRYLMNY- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. S8 TaxID=1837283 RepID=A0A1W5YTE0_9ACTN +-----RTVRSLFDDAGVRGWLHVAELERSARV-VLDPDEPVPMGSVYKIALMAAFCRLAD +AGRLDPCHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLREV-GT +DAVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDRAASPSSCA +FMRAAMGTQPW-AHRLASGFPDDVAVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] serine hydrolase n=1 Tax=Inediibacterium massiliense TaxID=1658111 RepID=UPI0006B69071 +-kNLKNKIENIINSIDGHKGVYIKDCSTHEVI-EIHENRKFHAASTIKLPILYDALLQIQ +NKKLSLNDTYQLKSSDIVDGSGILKLHIGLEVTLKDLLTLMIDVSDNVATNILHDLL-GK +DHINGSIKNLKLQNTFFARKLMISDSN----SYSYTTAKDLGILLEEFLICKNLNQAMAN +IGLHILSNQQY-NDRISHHL---------------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. HBUAS56010 TaxID=2571127 RepID=UPI0011774DB6 +--TLEKRVEAEIKSYDGFMGIYLDDF-HGNVV-KVHADETFETASAIKTLILASLFDEAE +KGNASLTDMLKYKEEHIVEGSGVLSALTPGALRVIDAATFMIIVSDNIATNMLIDYL-GI +DTINNCIKRLGCKDTILYNPIHFEQY----KRLGTSTPADYASVFIRLAKGELISTGADS +QMLEILKQQHY-NSMITKDFPPYITVASKSGSMD-GCRNDGGIVFTPYG-PYVIVMFHKQ +FSDAGHPAMVFGARVSRMILDQy +>[subseq from] Beta-lactamase class A n=1 Tax=Prochlorococcus marinus (strain SARG / CCMP1375 / SS120) TaxID=167539 RepID=Q7VBF0_PROMA +--TLESKWKEIDTKNNALKASGYVLLEDGRYA-ELNSNQIAPAASTIKIPILLICLKMVG +SGELKWNEKVTLTKDDVAEGSGWIRQPLGKEFFIHEIATEMIRVSDNTATNLLIRKIGGI +NTINQRFNMIGLKATKINSLLPDLQGT------NTTTTKELVKILELALKKNFLSIEARD +LFRDVLSTSVS-NKLIPDGVLEGLRVFNKTGDIGT-AYGDAALIQMPNNTNVFASFIVQG +PFND-QRSPELIRKLTAS----- +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. NEAU-G17 TaxID=2293572 RepID=A0A372JFG2_9ACTN +-------------EADVSGRLHAVDIDTGREL-GVGADDPVVLASVYKVPLLVAFFRLAA +RGVLDPAERITLRPDERTEGTGLSVMLDDVTMSLRDLALMMITVSDNAAADAVYARV-GR +DEVNAALDGLGLPGIRVTGDGRDLFDPLDPSRTSAGTPRELTGLLSLIWLDRAAPAAECA +LMRRMLGHQVW-PHRLSAGFPDDIRVSGKTGTLLT-LRNEIGVVEYPDGGRYAVAVFTRA +AEAVAPRADAVIGATARIAVE-- +>[subseq from] Putative beta-lactamase family protein n=1 Tax=Synechococcus sp. WH 8109 TaxID=166314 RepID=W0H0L6_9SYNE +--------ELAAQQSDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD +QGTLQWNEPLTLTEELVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLMIARAGGM +DAINARFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD +LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG +PFN-DPRSTELIRRLAAAMA--- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. N32 TaxID=2575514 RepID=UPI000E0F6CF2 +--------ELAAQQSDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD +QGTLQWNEPLTLTEELVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLMIARAGGM +DAINARFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD +LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG +PFN-DPRSTELIRRLAAAMA--- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis vancoresmycina DSM 44592 TaxID=1292037 RepID=R1G1Q4_9PSEU +--TVEAEIDGVFAAAGARGFLHAREIGGGPEV-AVGADDPVVLASVFKIPVAVAYAREVA +AGRLDETARTRVGPRYRIGGIGTAGCADDVEMSWRDLALFMLTMSDNAATDVVYHRI-GA +AAVDRVLADLGLRRTRLIGCCEDLFAVLDPERTTSSTPREITELLDAVWTDRAGEPAACE +RVRSMLARQIW-PHRLSSGFGSDVAVAAKTGTLP-AVRNEAGVVSFPDGRRFAVAVFTRA +NSERQPAVDAAIGKAGRLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536RI40_9CHLR +--DLTKQLDGLVGSFPGGAGIWIADPTVATPLfAHDPEEQVIAASLYKLGVLAEAERRVD +AGELHYNDTITIEPEDITTDGSF--EYAGTELTLDEALEAMITVSDNGAALALWHVL-GG +ANIDATLEKAGVKNFHVA---------FDDTEDNWATPHAIGTYFTLLAKRQLISPAASD +RMLARLERQQI-NDRLPAQLPADVVIAHKTGNLA-GVTHDAGIIFTKTG-PRVVVVMTWD +AL--DEDAANFISSIGSLVYS-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID8374 TaxID=2690354 RepID=UPI00136C9A21 +----EAAIRALFDDAGVRGWLHVAELEHSARV-VIDPDEQVPMGSVYKVPLMTAFWRLAD +AGRVDPLHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA +DVVDGVCAELGLPHTRIHGGVVGTFDVYDPAYKASSTPAEIARLLRAIWTDEAASPESCS +FMRAAMGTQPW-THRLASGFPDDVTVYGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Planctomycetaceae bacterium TMED241 TaxID=1986836 RepID=A0A424K032_9PLAN +--ALSQRWTQLAAAQDLEASAFLLVLDDGRYA-QMQADRAMPAASSIKTPILLVSLEQID +RGDLRWNEPLTLTKPVVGGGAGWMAKPLGTRFPTYEVATEMIRISDNTATNLLIQRAGGK +ERLNSRFQALGLTATKVNNWLPDLDGT------NTTSARDLSRAIALVDTGGTLSLRTRD +LFRDVMGTSVT-NTLLPKGLMQGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG +PFND-PRSTNLIRAMAAAMA--- +>[subseq from] serine hydrolase n=1 Tax=Arthrobacter sp. 18067 TaxID=2681413 RepID=UPI0013567D54 +------QLAEIFASAGATGSVHAREIGDGPEV-SLNPDGPVVLASVFKVPFAVAYSREVS +AGRLEETDRTTVTSRYRVGGLGTAGCADDVEMSWRDLAKFMMTMSDNAATDVLFHRI-GQ +AAVDAVLDDLNLKHTRIVGCGEDMDVILDPARTPSSTPRDIVTLLDAIWTDTAGSPEVCE +RVRSMMAQQIW-RHRMATGFDGNIVVAGKTGTLP-AIRNEVGVVTYPDDRQYAVAVFTKA +DTNPQPAIDASIGKAARLAVD-- +>[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Thermoanaerobacter thermocopriae TaxID=29350 RepID=UPI00056C682A +-qELKNNIQALISQYPGKYGVYFIDLNTGQTL-EINGYDSFIAASTYKVPLNFYLYTLIT +DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR +DNYIKFMEKLGAYVIPYS--------------SNITSPRDMSMYMKKLLDYVNAHPDTAG +ELMYYLKNTIY-NDRISYPIPDEIEVAHKIGNLSN-VVNDTAIVFHPAR-PYILTVLAND +VDSDDSYAYTVIRQISKMVYD-- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536AIX7_9CHLR +--DLTKQLDGLVGSFPGGAGIWIADPTVATPLfAHDPEEQVIAASLYKLGVLAEAERRVD +AGELHYNDTITIEPEDITTDGSF--EYAGTELTLDEALEAMITVSDNGAALALWHVL-GG +ANIDATLEKAGVKNFHVA---------FDDTEDNWATPHAIGTYFTLLAKRQLISPAASD +RMLARLERQQI-NDRLPAQLPADVVIAHKTGNLA-GVTHDAGIIFTKTG-PRVVVVMTWD +AL--DEDAANFISSIGSLVYS-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Firmicutes bacterium ADurb.Bin419 TaxID=1852892 RepID=A0A1V5LU53_9FIRM +-nELKSELEKYISGFQGQYGIYFIDLENNYEF-GINDTDEYIAASTVKVPLNYYVYREIA +DGEVDPEKTLAYNEADFEGGTGILQKLEGKTYKIKYLLELSITHSDNIATNMLLRYF-GR +KTLKKYMRAIGGTVV--------------DDNKNVSCPKDMAVYLKKIYEFCNSNGQLGE +ELKHNLCNTMF-NDRLPKLLPEEVEIAHKVGNQI-GAVHDVGIIYTE--KPYILAVMSND +VV-SDEESNNVIAEISKKVYD-- +>[subseq from] Peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 n=1 Tax=Granulicella tundricola (strain ATCC BAA-1859 / DSM 23138 / MP5ACTX9) TaxID=1198114 RepID=E8X686_GRATM +---LEGRLREIAAAHHGKVAVFAENLKTGETV-GLDADKVVQTASVIKLTILFDAMEQVR +AGKVKLDDAIVLKKSGQVGGSGILQLFDTPLLTLRDVLMLMITQSDNTGTNLAIDKL-GL +ANINGETRALGLKNTWLYKKVFTPATPMPADQKGKTTGREMAKVLERIYKCQFITAPKCT +EMLGMLNKQGS-RDGVPRYLNNDSAVGNKTGALE-AVRADAGIVSTKAG-PVVMCLFTYE +NATADNEGEVTIAKMSKAIVEAw +>[subseq from] Beta-lactamase class A n=1 Tax=Tepidimicrobium xylanilyticum TaxID=1123352 RepID=A0A1H2RB10_9FIRM +--SLEARINAEVFNFSGKLGFYASDF-KGNII-GVNSQEKFESASCIKVFVLTELYRQIH +EGKVSRNDLLEYTEEHFVVGSGVLRDLSYGILDAKSIATLMIIVSDNVATNILIDLL-GI +DNINNTCQNLGFKDTVLHNRI-DFNKY---DKLGTTTPKDYGLFFEKLYKRELWSQEISQ +EMIDIFKRQHY-NTILTRELPQYISIASKSGSMD-ACRNDGGIVFTPYGG-YVICIFTKE +FNDNDHESYRFGAKISRLVFDQy +>[subseq from] serine hydrolase n=1 Tax=Thermobifida halotolerans TaxID=483545 RepID=UPI000839772C +--ETHERIAALFDRAGVDARLHAVDLATGAEV-GLRADDQVVIASMFKILVLLEFARQVV +AGQVDPTERVTVSRENRLGGWGTAGCADDAELSLRDLAYFMMSVSDNTAADLIIRRI-GL +DTVQLLAAELGLARTRIVGGPHQVLEVLDPAHTTSSTPRELTRLLRMVWADEAGPAEACA +TVRACMARQIF-WTRIASGFDEGVRVSAKTGTLPS-LHMECGVVEYPDGGRYAVAVFAQS +RRLDLRDVDLAMGRAARTAV--- +>[subseq from] Beta-lactamase n=1 Tax=Thermoanaerobacterales bacterium 50_218 TaxID=1635288 RepID=A0A101F7M0_9FIRM +-rSLEQEIRKLLAEEEGTYGVYILDLHTQQFC-GINQEVVFHAASTFKIPMNLFLFQQIA +LNKINPQLKLTYKPQHYEGGTGILQFRYGTSYTIYELAKYSMVYSDNVATNMLLGYL-GR +KNVKDFMRSLGGKVV--------------DDRRNITCPRDMAYYMKALVAFWENYPEYGS +ILLNHLENTVF-NERIPKLLPSGTRVAHKIGNWATGSYHDVGIVFHPTH-PYIISLFSKG +VP-DRTHCFRVLQNLSLLVYN-- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006C07D76 +-qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMRDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID2119 TaxID=2690253 RepID=UPI00136ABC66 +---VERTIRSLFDDAGVRGWLHVADLHRPSAGvVVDPDEQVPMGSVYKVALMAAFCRLAD +AGLVDPRHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA +EAVDGMCAELGLPHTRIRGGVVGTFDVYDPAYKASSTPAETARLLRAIWTDEAASPESCS +FMRAAMLTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSVYTAVVFTQA +ARADLPRADAVIGAAARAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Microbacterium sp. K36 TaxID=2305439 RepID=UPI00109D492F +------------------------GVDDGPEV-AIGADEPVVLASVFKILVLTAFVRAVE +AGELDGRERTTVTARYRIGGVGTAGFADDTEVSWRDLALNMMSMSDNAATDVLYHRL-GA +AAVDRVITDLGLHRTHLIGCCEDLFAALDPERTTRSTPREVTTLLDSLWSDRAAPATACR +QARDIMARQIW-PHRLSSAFPSGVQIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA +ASL-ADRQPRVDASIGAAAYA-- +>[subseq from] serine hydrolase n=1 Tax=Slackia sp. ZJ350 TaxID=2709799 RepID=UPI0013EBB748 +--DIEASLSQLIEDAGANASFAYRYLSSGWDF-SVHGKEPHTAASMISLAVLTQLFDRID +AGDLSLDDEYELTEEAIVGGNGRLQDDPGTAYSLRDLVWYSIVESDNTATNMLIDIA-GM +DAINSEVARQGLEGTKLERHMMDTEAQ-KEGRENRMASDDAAAILNAIAQGAFYNEELSD +FAYDLLSQQKS-DSAVKDALPEGATYAFKSGSLEN-VYNEGGIVFG--EHPYVFVAFVEG +VD--EEEATALVKDAAALV---- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. UW106 TaxID=368495 RepID=UPI000E0FB173 +---LSQRWVELAQQTDLQASAYMLILDDGRFA-AMQAERPMPAASSIKTPILLAVLELLD +QGTLQWNEPLTLSQELVGGGAGWMASRPLGSFPTYEVATEMIRVSDNSATNLMIARAGGM +EQINARFQALDLPATVVNNWLPDLDGT------NTTSARDLSRAIALVDSGEVLGPRSRD +LFREVMGTSVT-NTLLPTGLMRGYRVYNKTGDIGL-AYADAGLIELPDGRRAVAGFLVKG +PFN-DPRSTELIRQLSAAMA--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNQ329 TaxID=1298879 RepID=UPI0004867176 +----------------VAGQLHARDIDTGAAL-AVAADTPVSTASVHKVCLLATLYREAE +HGRVDLTTAVDVPAAGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDTV-GI +EAVNRTMTDLGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA +DLRRTLGTQTW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAARLAVD-- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Microbacterium TaxID=2609290 RepID=A0A259SI12_9MICO +---TATSIAEIFADADAEGFLHARETEAGPEV-DSGADEPVVLASVFKILVLTAYVRAVA +AGTLDPTERTTVTARYRIGGIGTAGFSDDVQASWRDLAQNMMTMSDNAATDVLYHRL-GG +DAVDRVIADLGLRSTRLIGCCEDLFAALDPARTSASTPRDVTTLLNALWTDTAAPAEACA +QARAIMAQQIW-PHRLTSGFPNGVTLAAKTGTLPR-WRNEAGVVTYPDGRQYAVAVFTRA +RTLD-ERLPRVDASIGR------ +>[subseq from] Peptidoglycan-binding domain-containing protein n=1 Tax=Thermoanaerobacter kivui TaxID=2325 RepID=A0A097AT79_THEKI +-qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDLFIAASTYKVPLNFYLYTLIT +DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR +DNYIKFMEELGAYVIPYS--------------SNITSPRDMSMYMKKLLDYVNAHPDTAG +ELMYYLKNTIY-NDRISYPIPDEIEVAHKIGNLSN-VVNDTAIVFHPTR-PYILTVLAND +VDSDDSYAYTVIRQISKMVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Clostridia bacterium BRH_c25 TaxID=1734399 RepID=A0A101WGI8_9FIRM +--SLEARIKAEIYNFSGRVGLYVNDF-KGNIV-EINSEEKFETASTVKVFILAELYRQIY +EKKLTAEDILTYNKEHYVVGSGVLRAMDGVQLTVKNFAILMIIVSDNIATNVLIDLL-GI +DNINNTCNDLGLKNTVIHNRI-DFDSY---DKLGTTTPKDYGKIFEMIHNKELWSQELST +QIFEILKNQHY-NTILTKKLPQYIYIASKSGSMDN-CRNDGGIVHTPCGE-YVVSIFTKD +FKDK------------------- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. WAY2 TaxID=2663121 RepID=UPI00131F671B +-------------------------------V-SVDGDDLVVTASVYKLPLLVALCRAFD +AGTLSPTSTVRVNPADCTPPTGVSMFRDPVVMSWRDLALSMMTVSDNAAADLVLGGV-GL +DAVDRVLTDLCLARTRIVGGTADAHRAYDPSYASATTPQEMTALLDAIWTDRAVSPVQGE +FIRQVMAAQVW-QHRIRSGFPADVTVAGKTGTIG-AIRNEAAVVTFPGEIPVAVAVFTRA +ARADLPVVDQAIGRAAQIAVS-- +>[subseq from] Uncharacterized protein n=1 Tax=Peptococcaceae bacterium TaxID=2052179 RepID=A0A3B8NQD0_9FIRM +-rSLEQEIRKLLAEEEGTYGVYILDLHTQQFC-GINQEVVFHAASTFKIPMNLFLFQQIA +LNKINPQLKLTYKPQHYEGGTGILQFRYGTSYTIYELAKYSMVYSDNVATNMLLGYL-GR +KNVKDFMRSLGGKVV--------------DDRRNITCPRDMAYYMKALVAFWENYPEYGS +ILLNHLENTVF-NERIPKLLPSGTRVAHKIGNWATGSYHDVGIVFHPTH-PYIISLFSKG +VP-DRTHCFRVLQNLSLLVYN-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces viridifaciens TaxID=48665 RepID=A0A5P2UXS2_STRVF +--AARARIAAAFAEAGVTGLLHARDLDTGAEL-ALGADTPVSTASVHKLCLLVTLYREAA +AGRIDLTRPVDLPATGRTPGRTGLSAMLDAALSLRDLAYLALAVSDNAAADVLWDEI-GL +DTVNRTMAELGLTRTIAVHTVRELFAVLDPAFTNRSTAREMTALLAALWHGDACPGEPGA +ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA +AATSLPTADAAIGTAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00099BB8DE +---------------------------GGREV-AVGADTPVVIASVFKVLLVLEFARQAV +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFALSVSDNTAADVLLDRV-GL +DTVRLLAASLGLERTRITGGPRDLLEVLDPRHTTASTPRDITRLLRLVWDDTAAPPDACA +FVRDLMARQVF-RHRLVSGFPDDVAVAAKTGTLP-GLHMEAGVARYPDGAHYAIAVFART +HDL-AASRTAVDAAIGRAAA--- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2G4IDB8_9BACT +--------DAELVRFPGKAGVWVKHLTTGEEA-GVHAHDTFNTASVIKIPVLVLAMQLAD +QGSLSLAERVTIGASEMRGGSGIFRYDPGLQPTFRDVLTQMIITSDNTATDIAIGKTGGV +DAVNRWLVASGYGGTKLSMTTADLFASDRSYWLGEMTPHATGRMLEAIQRCHVASKAACA +DMMRMMRGQQSGARRLPHFLN--VPVAHKTGDFPPALANDVGVIFTRSG-PVVVAFFANA +IEGPYGEAEDRIGRIAQHIVDYf +>[subseq from] Serine hydrolase n=1 Tax=Tissierella sp. P1 TaxID=1280483 RepID=A0A265QC07_9FIRM +--SLESRINAEVYNFSGRIGLYANDF-KGNII-EINSDDKFETASTIKVFVLAELYKQIH +ENKINPHKILKYEKENYVVGSGILRDLDYGVMTAKSFATLMIIISDNIATNVLIDLL-GI +DNINNTCADLGLKDTILHNKID-FEKY---SKLGTTTPRDYGRFFELLYKKELWSKEVSE +EMIDILKKQHY-NTILTRDLPQYISIASKSGSMD-ACRNDGGIVYTPYGG-YVISLFTKD +FVDNDHESYRFGGKVSRLMFD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus jostii TaxID=132919 RepID=A0A1H5MFH2_9NOCA +--------------------------DDGADI-AVGADDLVVLASVYKLPLLVSLCRAFD +SGSVVPTATVRVNPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL +ESIEQMLSELGMTSTRVIGGTADAHRAYDPSFASATTPRDMTTLLDAIWTGRAVPGPQGE +FIRQVMAAQVW-QHRIRSGFPSDVDVAGKTGTIG-AIRNEVAVVTFPGEIPVAVSVFTRA +ARADLPVVDAAIGHAARIAVT-- +>[subseq from] hypothetical protein n=1 Tax=Actinomadura flavalba TaxID=1120938 RepID=UPI0004782D89 +-------VAEAFRAAGVTGRLHARDIDTGGVV-DVGGDEPVVLASVYKVPLLVAFYREAA +AGRLDPAERITLPAGGRSPGPTGTSVMLDDVLSLRDLALLMITVSDNGAADTIYDYV-GR +DTVNAAMAAFGLTRTRVTGNGRDLFAALDPTRTSASTPAEMTALLALIWRDEAAPPDACM +HMRRMLGLQVW-PHRLSSGFPDDVHVAGKTGTLPT-IRNEIGVVEYPDGGRYAVAVFTRS +LLAVLPEADAVIGTAARLAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Kitasatospora aureofaciens TaxID=1894 RepID=A0A1V0VY74_KITAU +--AARARIAAAFAEAGVTGLLHARDLDTGAEL-ALGADTPVSTASVHKLCLLVTLYREAA +AGRIDLTRPVDLPATGRTPGRTGLSAMLDAALSLRDLAYLALAVSDNAAADVLWDEI-GL +DTVNRTMAELGLTRTIAVHTVRELFAVLDPAFTNRSTAREMTALLAALWHGDACPGEPGA +ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA +AATSLPTADAAIGTAARLAVD-- +>[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Thermoanaerobacterium thermosaccharolyticum TaxID=1517 RepID=A0A223I0B3_THETR +-qELKNNIETLLSQHPGKYGVYFIDLNSGETF-DINGYDSFVAASTYKVPLNFYLYTLIT +EGKIDPNMEVQYTSQDYESGSGSIQYDPVGTYTIRELSRRSIEESDNIASNMIMRVV-GY +DNYLNFMKSMGANVIPY--------------TSNITSPRDLSLYMEKLLNYANAHSSTAG +ELLNYLENTIY-NDRISYPLPSNITVAHKIGNLSD-VVNDTAIVFYPSK-PYILTIMGNN +VDSDNSDAYTVIREISKMVYD-- +>[subseq from] Peptidoglycan-binding protein n=1 Tax=Thermoanaerobacterium thermosaccharolyticum TaxID=1517 RepID=A0A231VMD7_THETR +-qELKNNIETLLSQHPGKYGVYFIDLNSGETF-DINGYDSFVAASTYKVPLNFYLYTLIT +EGKIDPNMEVQYTSQDYESGSGSIQYDPVGTYTIRELSRRSIEESDNIASNMIMRVV-GY +DNYLNFMKSMGANVIPY--------------TSNITSPRDLSLYMEKLLNYANAHSSTAG +ELLNYLENTIY-NDRISYPLPSNITVAHKIGNLSD-VVNDTAIVFYPSK-PYILTIMGNN +VDSDNSDAYTVIREISKMVYD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces lavendulae TaxID=1914 RepID=UPI0010084935 +---VERTIRSLFDDAGVRGWLHVADLHRPARV-VVDPDEQVPMGSVYKVALMAAFCRLAD +AGRVDPRHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA +EAVDGMCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPAETARLLRAIWTDEAASPESCS +FMRAAMLTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVDFGDGSVYTAVVFTQA +ARADLPRADAVIGAAARAAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Parcubacteria bacterium TaxID=2053309 RepID=A0A3A4V0Y7_9BACT +-nSLENAVQSALSESTGTYGVVIKNLNTDEKY-YLNEHRVFKTASLYKLWIMAVAYEQIQ +TGKLQKDQILTEDVSSLNDASESAEKTEGTILSVTEALNKMITISDNYSALLLSAQV-KL +SNVALFLKNQNLTESNIGTEDKS---------YPTTTPSDIALFFEKLYKGELANEKYTK +EMIDLLKNQRL-NNKLPKYLPQNTIIAHKTGELYN-ITHDAGIVYTPTEN-YIIVVLSET +DNP--EKAVEIIGQISKNVYNYf +>[subseq from] serine hydrolase n=1 Tax=Rudanella lutea TaxID=451374 RepID=UPI000375EE57 +---LERDLRALLGAFRGDVGLYVRNLRTGETV-AINADTLFPTASTIKIPIQCGLFDKIH +RGELKYSAELVYKDSLHYDDGIVGQLKDGARLPLSQVVMLMETTSDNTASLWCQAMAGGG +AAINAWLDANGFAQTRVNSRTPGRAAFQKQYGWGQTTPRELAELLAYIRAGRAVSPDASD +RMYRNLCRQYWDGDGL-SQVPPEVKVASKNGAVNR-SRSEVVLVHAPHGE-YVYCLMTKN +AQERTNEGFALLRAVGARLWKHf +>[subseq from] serine hydrolase n=1 Tax=Dactylosporangium aurantiacum TaxID=35754 RepID=UPI0005254590 +--------EETFAAAGVRGRLHARDIDSGRSI-GVGADEQVVLSSIVKVLLVLEFARQVA +VGALDPAERVVVGAGDRFGGWGTAGCADDVELSLRDLAYFAMSISDNTAADVLLHRIGGP +DLLALLAAELGLTRTRVVGGPRQMLEVFDPRRTTSSTPEELTRLLGMLWRDEAGPPAACA +AVRGLMARQLF-WTRLRSGFPAEVRVAGKTGTLP-GLAMEIGVVEYPDGGRYAVAVFVDG +GRTPRIEVDTALGRAAAAAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora pallida TaxID=145854 RepID=A0A1C6RJM1_9ACTN +-----------FERVGVEARLHVVDVDSGREV-GIRADEQVVIASVFKILLVLEFARQAV +AGQVDPTERVLVRAEDRLGGWGTAGCADDVELSLRDLAYLTMSVSDNTAADLLMRRV-GP +DVVPLLAAELGLARTRVVGGPRQVLEVFDPAHTTSSTAREITRLLTLIWRNEAGPATACA +MVRELMARQMF-WTRLASGFPPDVRVAGKTGTLP-GLHIEAGVVEYPDGGRYAVAVFAQT +QRLTARDVDLAMGEAARTAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Gordonia terrae C-6 TaxID=1316928 RepID=R7Y8U0_9ACTN +-----------------------------VEF-SHDADAPVVLASVYKLAVLISLCRLAD +RGDIDLAASITVEPTRWAPGPTGLALFTDPVMTWRDLATSMMTVSDNVAADVILTHI-GL +PRIHADLNQLGLAHTRIVGGVAELHEAYDAAYSSSATPRDCTTLLDAIWTDRAASAASCE +FIRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AVRNEVGVIEFPGELPVAIAVFTMS +ARSELPEVDRAIGEVARSVVT-- +>[subseq from] serine hydrolase n=1 Tax=Clostridiaceae bacterium MJB2 TaxID=2498136 RepID=UPI00101C8AD2 +-kTLKNKIENIINSIDGHKGIYIKDCSTNKVI-CINENRIFHAASTIKLPILYDALLQVQ +NKNLTLDDTYHLKASDKVDGSGILKLHIGLEVTLKDLITLMIDVSDNVATNILHDLL-GK +DHINKSIQNLNLKNTFFARKLMICDSN----SHSYTTAKDLGLLLEEFLVCKNLNKDMAN +IGLDILFNQQY-NDRISH------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Cyanobium sp. TaxID=2164130 RepID=A0A4P5VGP9_9CYAN +--DLSQEWAKLAAAQGLTASGYLLVLDDGRYA-QLQSDLALPAASSIKIPILLVGLETLD +AGRLRWNDLLPLTSEVRGGGAGWMGNKPGSRFRVYEAATEMIRISDNTATNLMIKRLGGS +VAVNQRFNGLGLKATVINNWLPDLNGT------NTTSSHDLARSIALVDSGEKLSPRARD +LFREIMASSRT-NTLIPAGLLKGISALNKTGDIGI-AYADAALIQLPNGQRAVAAFLVKG +PFND-PRSSELIRAMAAATA--- +>[subseq from] serine hydrolase n=1 Tax=Virgibacillus subterraneus TaxID=621109 RepID=UPI000B870082 +---LETGIRTIINKTIDRFSIFIH-TDDGQIA--INAYEPRKAASLIKIPILIEAFRQLE +SDQFRSDTLVYIEQDMKVGGAGVINYLTSSNYSYKNLMELMIIISDNTAANIVLDKV-EM +YQVNALARHLKCEHTEIQRKFMDIASQ-SAGLENYTSAYDMYHFLSTIANSNTISDNSRS +QIVEILSNQQF-GDKLASYLPSDVKLYHKSGELD-GVEHDAAILEYQNKR-IEAVVMSEG +WE-NNGIGKRHIAEIGNLLIDY- +>[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A537JYP3_9BACT +-sKLQNKIEDAIQGFNGDIGIYIKCLRTGKTV-SINADTVFPTASIVKVPILLGIMDKIQ +KGELAYDSTLVYKDSLLYEGVDILGSFKNDEILLKKVMMLMLTTSDNTASLWLQSLAGKG +TRINEILDSLGLVYTRVNSRTPGRENNRTEYGWGQTTPKEIGTIFEKIYRNEIFSAAACD +RMMRSLGRNYWDLNEAISQIPPYIEVFSKNGCVN-AVRSEVLLVNAPHN-PYIFCIFTKN +NKTHDNEAWTMARKISLMLWRYf +>[subseq from] Beta-lactamase class A n=2 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1I6ZCZ3_SELRU +--SLAQVVESLSNSDSTRYALFVCYPAQDREV-YSYHSAPMRSASMIKVFILGTAMEKIR +DGQLDLYQNLTLHGYDKVGGAGVLAGYANGTLSLDKVMRLMITESDNTATNMLIDLL-GM +ASINEYMQRNGYTDTILQRKMMDSQA-MAAGRENYTSVNDLGNFFVKLYHRSCVSPQLDD +VMLGYLEGQTD-TECFPAALP-GIMICHKTGELY-GLYDDGGIVYQEGN-PFIIVGMTDN +YS-SRGRAISILRQMAQAAAN-- +>[subseq from] Beta-lactamase n=2 Tax=Hymenobacter nivis TaxID=1850093 RepID=A0A502GB41_9BACT +hpALRATIARLAAGAPAKVGVALRVLETNDTL-SYHNRQPYPMMSVFKLAIAMQVLHEVD +RGHLRLAQQQLLTKADLPGHSPLRDKYPSGNVSIQELLTYMVTVSDNNACDILLRLVGGP +AKLTAYVRQLGVWPFVAEVSEAQMAAVWRNQYRNWSYPS--------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=2 Tax=Corynebacteriales TaxID=85007 RepID=A0A2W6RI48_9ACTN +----------------------------EREF-GWAADDPVVMASVYKLPLLLALCDLAE +IGQIDLTATVVVDPADWAVPTGIATLHDPVTLSWRDLAVQMMVISDNAAADVILDRV-GL +PRVQEKLDALGLTETRVVGGMAELQQAYDPALASATTPRDATRLLQLIWTDQAVSAQMSE +FVRSTMRKQAW-QQRLSSGFPLGVTIAGKTGTLG-AIRNEIAVVEYPGEHPIAVAVFTLA +ARLSLPTVEAAVGRAARIAV--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sioyaensis TaxID=67364 RepID=A0A4V1NQA4_9ACTN +---TQDHIRTAFADAAVTGWLHACDIDTGAEV-GLHPDHPVVTASVHKLCLLVALHQRAE +QGDFDLTEQIEVPPTGRTFGLTGLGAMLDPAVSLRDAAYLMMSVSDNIAADLLLERV-GL +DAVNRTTTQLGLAHTLAVHTFRQLLDALDPARTNRSTPRDMTRLLSCIWRDEAGTPDHGA +AIRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA +ANATLPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Slackia sp. ZJ119 TaxID=2709798 RepID=UPI0013EC8574 +--DIEASLSQLIEDAGANASFAYRYLSSGWDF-SVHGKESHTAASMISLAVLTQLFDRID +AGDLSLDDEYELTEEAIVGGNGRLQDDPGTAYSLRDLVWYSIVESDNTATNMLIDIA-GM +DAINSEVARQGLEGTKLERHMMDTEAQ-KEGRENRMASDDAAAILNAIAQGAFYNEELSD +FAYDLLSQQKS-DSAVKDALPEGATYAFKSGSLEN-VYNEGGIVFG--EHPYVFVAFVEG +VD--EEEATALVKDAAALV---- +>[subseq from] Serine hydrolase n=1 Tax=Fibrisoma montanum TaxID=2305895 RepID=A0A418MHK9_9BACT +--KLERKLTDLLAGFRGDVGLYVRHLKTGRTV-SLNADTLFPTASTIKIPIQCGLFARLA +TGELAYQQELIYRDSLHYDDGIVGSLKDGARIPLSQVVMLMESVSDNTGSLWCQALAGGG +QAINSWLDANGFRQTRVNSRTPSREANRKQYGWGQTTPRELAELLVYIREGRAVSPDASE +RMYRNLGRQYW-DGDALSQIPPDVQVATKNGAVNQ-SRSEVVLVHAPHGE-YVFCLMTKN +QQDETNEGAMLLRQVSALLWQYf +>[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces argenteolus TaxID=67274 RepID=A0A561QBZ5_9ACTN +---VERAIRSMFDDAGVRGWLHVADLHHPAQV-TVDPEEQLPIGSIYKVPVMVAFCRLAD +AGLIDPRRRLTLEPDERVPPTGISVLHDAVTMSLRDMVVLMMTISDNASADAVLRAV-GP +DVVDAVCRDLGMPDTHIRGGVVNTFSVYDPAFKASSSPADMARLLRAIWTGQAASDDRCA +FMRKVMRQQPW-THRLGSGFPDAVTVYGKTGTLG-ALRHEAGVVELADGSTYTAVVFTHA +ARSDLPRADAVIGAAARVAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Nocardia sp. CS682 TaxID=1047172 RepID=A0A4P7H2U8_9NOCA +-------VQEIFRNVGVQGWVHARCFDCGAEV-GSGADEPVVLASVVKVPLVLEFARQVA +AGQLDPTDRVRAGAADRLGGVGTAGCHDDVDLSLRDAAFFAITLSDNTAADLLFERV-GI +DNVRSLVRELGLAGTRIVGAPRHIVQALDPQRTTASTPREMTRLLTLIGEDRAGPAEACR +WVRDLMRQQLN-WHRLAAAFPPEVGVWAKTGTLP-GVRNEIGVLEYPDGSRYAVAIFTRA +GTQRLPAVDRAIGAAAAHAVD-- +>[subseq from] serine hydrolase n=1 Tax=Chitinophaga sp. Cy-1792 TaxID=2608339 RepID=UPI00141FB282 +-kKLEAILAPMLKDFHGQVGIYVHHLKKNKIV-AIDADTLFPTASMIKTTIQAGIFNKIA +AGELKYNQELIYKDSLLYAGEDILGSFKNGEIYLDKVLMLMLTMSDNTASLWLQGLAGGG +LTINSWLEANGFKQLRVNSRTPGREVNRKQYGWGQTTPYEMARLMEMIYRGVVIDKNSSE +RMYRNLTRNYWDGQGL-LQVPENVRTASKNGAVDE-SRSEVIMVNAPHGD-YVYCIATKN +NANRDNEAWQLLRRVGYAIWKHy +>[subseq from] Uncharacterized protein n=1 Tax=Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933 TaxID=398512 RepID=A0A0L6JRM9_9FIRM +--KIKSTLLGYLKGVDGHYGVYYYNLFTNESF-GINEYEEFVAASTVKVPINLYLFEKIK +SGDVNLTGTLKYLRNDYEGGTGIIQTSFGKKYTIRQLSKLSITHSDNVATNMLLRFI-GI +GNVKNYMRQIGGTVV--------------NDGKNVSCPRDMGIYMKCVYEFCNNNSDLGK +EFMDNLLNTKF-NDRIPALLPQDIKVAHKIGTQVN-TINDVGIVFTD--RPYIISIMSKE +VDE--NTAPQVVAKISKIVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8LTD7_9BACT +---LDIRIRNEVAPFKGKVFIFAKNLDTGAAY-TFNGDERVRTASTIKIAVMIEVFARVA +EGKAKWTDELVLTKAARFSGSGILPELGDGLLTLQDCVRLMMTLSDNTATNMVLDYLSGT +DSVNDRMNLLGFKATRIMRRVGSGGESKAGKEPGSTTPHEMVQILEKLDRGEVVTQEASK +QMIDLMKREQS-RYAIGRTTP-EIPMASKYGALD-ALRSCVAVLYTKQGR-IAIAITVDE +M---------------------- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 01416 TaxID=2203196 RepID=A0A429C7B3_9PSEU +-----AEIEAVFANAGARGFVHAREVGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVA +AGRLDDTERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ +EAVDRVLTDLGLTRTRLIGCCEDLFAVLDPERTTASTAREITTLLDAIWTDRAGDPAACE +RVRAIMAQQIW-PHRISSGFPAGVTIAAKTGTLP-AVRNEAGVVTDVDGRRYAVAVFTRA +ESDRLPAVDSAIGEAAGLAVA-- +>[subseq from] serine hydrolase n=1 Tax=Kribbella sp. NEAU-SW521 TaxID=2185285 RepID=UPI000DD300B5 +-----GRIRAIFEDAGVRGWLHATPLDRPHETiEIDSDAVVPLASVYKLPLLVGFCQLVD +QGRLDPREQVTLLPEARTPGPTGLSLLADPIISRRDLAVLMMTVSDNAAADALLDHV-GL +DRLGTILGELGLTRTRIRRGAADNLRVYEAANASSGTARELTRLLSRLWTGDLLSAEQTH +FARTTMERQIF-QHRIAAGFPDGVRVAGKTGTFG-ALRHEAAVVTLPGGDAYAVAVLTLA +ARSDLPRVDAAIGEAARVAVD-- +>[subseq from] serine hydrolase n=1 Tax=Actinobacteria TaxID=1760 RepID=UPI0006905774 +---------------------------VEREF-GWAADDPVVMASVYKLPLLLALCDLAE +IGQIDLTATVVVDPADWAVPTGIATLHDPVTLSWRDLAVQMMVISDNAAADVILDRV-GL +PRVQEKLDALGLTETRVVGGMAELQQAYDPALASATTPRDATRLLQLIWTDQAVSAQMSE +FVRSTMRKQAW-QQRLSSGFPLGVTIAGKTGTLG-AIRNEIAVVEYPGEHPIAVAVFTLA +ARLSLPTVEAAVGRAARIAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Parcubacteria group bacterium 21-54-25 TaxID=1970248 RepID=A0A257TFU1_9BACT +-----DKINEILRKADGIWGAAVKPIGNGFLF-EHNANGEFRAASVGKVPIALYLLYLVE +TNGARLEDRFVVSAEYYQPGSGVLSRLTPGVLTLKDLVVLMLTVSDNTAADLLVKAH-GA +DKINNYLTSLGFQKTQLGIKDDDFDF-------GATTPREMAVMLEGIYSARYLNREHSD +LLLQIMKECEN-QLGIKRLLPAKLETANKGGSHDR-LRNDIGIVFTK--QPYVIAIFSKD +LPKPDNPGWLTIARLSAE----- +>[subseq from] Serine hydrolase n=1 Tax=Pararcticibacter tournemirensis TaxID=699437 RepID=A0A5M9H482_9SPHI +-kKLTALLQDAAKGFDGTVGIYVQNLKTNKTA-AINADTLFPTASMIKVSILCGVMDKIE +KGELLYNQKLVYRDSLLYPGVDILGSFKDNEIDLSKVAMLMITMSDNTASLWLQKLVSG- +TYINNWLDQNGFKVMRVNSRVEGREPVRKIYGWGVTTPYEMCRLFTLIRNGKVVSPAASE +RIYRNLVRIYW-DEGALSQIPPYVQAASKQGAVD-ASRSETVLVNAPHGD-YVFSVITKN +NKSETNQAHQLIRRISSLLWHYf +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. HB1133 TaxID=2508568 RepID=UPI0014081DCA +---LSQRWVELAQQTDLQASAYMLILDDGRFA-AMQAERPMPAASSIKTPILMAVLELLD +HGTLQWNEPLTLTQELVGGGAGWMASRPLGSFPTYEVATEMIRVSDNSATNLMIARAGGM +EQINARFQALDLPATVVNNWLPDLDGT------NTTSARDLSRAIALVDSGEVLGPRSRD +LFREVMGTSVT-NTLLPTGLMRGYRVYNKTGDIGL-AYADAGLIELPDGRRAIAGFLVKG +PFN-DPRSTELIRQLSAAMA--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC28_STAAU +---HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP +--YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASXKYSDNTANNKIINZIGGI +KKIKKRLKKLGDKVTNPVRYE--------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. B7740 TaxID=1564114 RepID=A0A0D5AGS3_9NOCA +--TTDEQLRAVFADAGCRGWVRAERIDGTGTVvDYEGDDPVVAASVWKIVLLVAVARAFD +EESLTATDSVRLVPAQCSPPTGIASFADPVTMSWRDIARSMITVSDNAAADALLGAV-GL +DAVARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTILRSVWLGTAASPAQCR +YMKDVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA +ARMDLPLVDQAIGHAARIAV--- +>[subseq from] Beta-lactamase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A564ULA7_9FIRM +--TLEKRIAAELYSYQGKMSVFVDDL-HGRTV-EIGADEEFETASTIKAYILAALYLQAS +RGKASLEEKITYKPEHFVDGSGMLRAGVGASLKVKDAATMMIICSDNIATNMVIDYL-GL +DTINACIREMGFAHTVLHNPL---HFDIYSD-LGTTTPRDYASLFAQVAKGTLVSAEASA +EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A3E2X4L9_9FIRM +--TLEKRIAAELYSYQGRMSVFVDDL-RGSTV-EIGADEAFETASTIKAFILAVLYLQAS +RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFEHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA +AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE +FHD-------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7Z476_9BACT +------AVAAGSRLCGCRIGVAARHLESGLAY-EHDAGDIFEAASIIKIAVLTEAIAGVR +EGSIDLAERWTLTSPRKASESGWLKLFDPGLPTWNDMLTLMIGPSDNTATNAWIERL-GI +DRINARMESLGFSHIRLLSLLPWLDERWKGLKFGSVTPREVAEWLARVARGELLDAESSH +RMFQYLEASPS-RSRLARRFSSSALWAGKTGTMS-GVRNDSGILRTEKG-RFVLVVLTDG +SSNATHPATVAMGEIARAIVDEw +>[subseq from] Beta-lactamase class A n=2 Tax=Virgibacillus salinus TaxID=553311 RepID=A0A1H0Y7J0_9BACI +---LETGIRTIINKTIDRFSIFIH-TDDGEIA--INAYEPRKAASLIKIPILIEAFRQLE +SDQFRSDTLVYIEQDMKVGGAGVINYLTSSNYSYKNLMELMIIISDNTAANIVLDKV-EM +YQVNALARHLKCEHTEIQRKFMDIASQ-SAGLENYTSAYDMYHFLSTIANSNTISDNSRS +QIVEILSNQQF-GDKLASYLPSDVKLYHKSGELD-GVEHDAAILEYQNKR-IEAVVMSEG +WE-NNGIGKRHIAEIGNLLIDY- +>[subseq from] serine hydrolase n=1 Tax=Terrisporobacter glycolicus TaxID=36841 RepID=UPI00039FC162 +-----------LKNMQGDVSFYYKNLTTNNTI-GYNEEKIMLAASVIKLTILVEAFKQIK +EDKIKKEEFFITCEDDKVPSCGALNYMREDLVTLKDLYVLMIILSDNYATNILIDKL-GM +DNINKTIKEIGLKNTVLNRKMFDSEKA-ELGLENYISASDVGYLLEKMYNKDLIDEKSSE +EMISILKNQRL-NGKMPHSLKPKIEIAHKTGEDTN-ITHDVGIVFAK--EPFIVCFCGNN +V--NVPEYERLMQDITYD----- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. 311R TaxID=1617904 RepID=UPI00067EA304 +-----ASIADVCDDANASVAFHVRSLDGKFEI-GSAADARSVTASTYKVPVMLEVAAQAS +EGRLRLADRIKVPADRRTIPSGISAMTDDVEVSIRDLALLMMQVSDNTATDILQEMV-GT +ESIMRRLRALGLNSTDITTDCDGIISSLNARGGNTSTPREMTELLSLIWTDKAADAEACA +EVRRVMGLQFA-PHRLSSAYVDGPTISGKTGTFLAGVRNEVGVVDFGDGDVYLVAIFLRD +KSNNNAKVDAAIGKIAALAID-- +>[subseq from] HGF-1 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=I0AXX1_9ZZZZ +------DIKEVIQEKKATVGVAILY--QDKIF-TLSDNQQYPLMSLFKFHVTVAALKKMD +REHIPLDSTVYITREQMHEYSPLRNKYPNQGISLRDIITYTIIYSDNNTCDWLIDFAGGI +KKVDTFIKSLGIKKLNLTETEHSMHENIMNSYNNWSSPLSVVQLIKKIYTDEILSATSFA +FLEETMLNCSSGE----------------------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Senegalia massiliensis TaxID=1720316 RepID=UPI0013620160 +-------LESIINEDKLKYSLYVEDLKTNKIIfDINSDAEVTSASMIKIFIMAEAYSQIS +KDEFMSQKIVNIDRDNIVGGSLIKN-LSNYCYSIKDLIFLMMNLSDNTATNQLVDIL-RI +ENINKFINEEGLKNTVINRKMMDFERK-KQGFDNITSASDVAHILKKIYYKDLIDTDASV +NMMNIMKKQMDNRMMARNIDKSNTKIHHKTGNIPY-TNHDAGIVIFKDVE--YLFVMLTW +DGVDNIYGRKVIGEVSEKIYNDf +>[subseq from] Uncharacterized protein n=2 Tax=Synechococcus sp. KORDI-49 TaxID=585423 RepID=A0A076HE25_9SYNE +--ALSQRWTQLAAAQDLEASAFLLVLDDGRYA-QMQADRAMPAASSIKTPILLVSLEQID +RGDLRWNEPLTLTKPVVGGGAGWMAKPLGTRFPTYEVATEMIRISDNTATNLLIQRAGGK +ERLNSRFQALGLTATKVNNWLPDLDGT------NTTSARDLSRAIALVDTGGTLSLRTRD +LFRDVMGTSVT-NTLLPKGLMQGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG +PFND-PRSTNLIRAMAAAMA--- +>[subseq from] Uncharacterized protein n=1 Tax=Virgibacillus indicus TaxID=2024554 RepID=A0A265NBQ8_9BACI +--QLDKAIQLLVSDVRQNFSIAI-DTPDGH-I-RIDAAKKRKAASLAKIPILIEAIRLAE +ENKLSLEKLIFIEKAAMVGGSGVINYLTDSNHSYQNLLELMIIVSDNTASNLLLDTV-GM +DNINKLAQILNCRETNMERKFMDQQAQ-QEGHENYTSAQDMITFLKLISENDFLSGESRK +QMLRILLNQQF-KNKLAKNLKDQIKIYHKSGELH-GVEHEAAIYNYKNKK-MEVAILSEG +WTRN-GIGQEYIAEIGKLLINYf +>[subseq from] Serine hydrolase n=1 Tax=bacterium (Candidatus Stahlbacteria) CG23_combo_of_CG06-09_8_20_14_all_40_9 TaxID=2014296 RepID=A0A2G9XXJ0_9BACT +--VLQRQIETSVENFHGDVGIYVRHLSKNITA-GINENDLFPTASMIKVPILVKIFDKIE +KGELTIESRVIYYEDSINYGDDAISRFKDGEISIGKLMAHMITFSDNHAGIWLQELAGSG +TAINEWLNQEGFCSTRVNSRTPGREDDYEQYGWGQTTPREMAELLVMIREGRAVSKRASD +DMYRYLTRIYW-DGNALSQIPPTIQVASKQGALDQ-SRSEVLLVNAPHGD-YVFCIITKN +QKDTSNEGSVLIRNVSNLLWNYf +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Roizmanbacteria bacterium RIFCSPLOWO2_01_FULL_45_11 TaxID=1802070 RepID=A0A1F7JGX3_9BACT +--DLANAITEIIQKEEGEYSVLFSDHKSSDYI-SVNHKSAYTAASVIKIPLLAAIYQLAD +AGEISLDEEITILRSDVQDWGTGTIRYESQPHTVREICQLLIEKSDNTAAYVITNRVIGP +EKIQQIISRWGLSQTNVAE--------------NLTSNQDIEKLMRMMFDGKIADEKLTT +EMISWMDDSDY-ENRLSGLLPESVNVYHKIGNEVR-IIHDVGVIEFDGH-RYYLGILSRE +VP-DLERAERTIGTLSKTVYDY- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02460 TaxID=1703941 RepID=A0A1Q5JHB1_9ACTN +---TLTQLRAAFTDAGVNGWMHALDIDSGTEV-DYQGSQLVSTASVHKLPLLIALHERAA +AGDIDLTEQVDCPPDGRASGPTGLAAMADTALSLRDLAYLMMAVSDNASADVILRRV-GL +EAVNRTTARLGLARTHALHSFGAMMAALDPAQSNRSTPRELTQLLATIWRDTACTPDHCA +SMRRLMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRGEVGVVQYPDGGRYAIAVFTRT +ASAIVPAADAVIGIAARIAVD-- +>[subseq from] Putative beta-lactamase n=1 Tax=Clostridium chauvoei JF4335 TaxID=1351755 RepID=S6FAK6_9CLOT +-----KEIKKYLESRIGTYGFFFEDLKSGFIY-GYNENVKMVAAGCMKLPIAVSLISAVE +HGKVDFMDKIKIDGKDKVYGTGIIHEFNEREYTVFELLVAMLIQSDNTAANKIIDII-GM +EQINKDIQEMGLKNTTLNRKTTDE-RKPKNEVENITTASDLSKIWKHLYKGTFLNADNSQ +MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKN-GVENDTELIQLSKGN-FAFTIMSMN +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Megasphaera sp. Marseille-P4857 TaxID=2045301 RepID=UPI000C7ACAE2 +---------------AGELAVYCRRLGGEEPF--LLRDRPMAAASLIKIPIMIEAFRQER +AGRISFSARWPVRAA--VPGGSFYTLPINTPVTTAVLIEHMIVESDNTCANMLLDIL-GM +AAVNDCIDGLGLKGTRLRRKMMDFTAA-AAGRENVTTPGDMGRLMTLLAEGRCLGRRADA +AMCGILSRQED-NCVIPAQMARSLRIDHKTGELA-GVYHDCGILYAPQGK-LILCLMADG +IKNEA-QAIYDMSYLARA----- +>[subseq from] Serine hydrolase n=1 Tax=Ruminococcaceae bacterium TaxID=1898205 RepID=A0A348T238_9FIRM +---LERRIDAELCGLDAKMCVYADDL-HGHVV-ERGADDEFESASTIKIYILGCLYAQAE +AGKASLDAELTYEARHFVDGSGLIRSLGEGALRARDVATLMIVVSDNIATNMLIDYL-GL +DTINAFIRSIGCTHTKLHRSLRSDNW---SEKLGTITPRDMGRFFALLAKGELVSPQASD +AMRNVFRQQHY-NTMLAGSIPPYIYVASKSGSMD-ACRNDGGLIHTPYGD-YVLVMMCTD +FANKLEVND-------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces katrae TaxID=68223 RepID=UPI0009974066 +----LHRIRAAFAEAGVTGRLHAVDIDSGTEI-DAGADQPVVTASVHKLCLLVALHEHAA +AGRVDLGEQVECPPGDRTAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL +DGVNEATARLGLTRTLAVHTFRSLFAALDPAHSNRSTPRDMTRLLAAVWRDEACIPEHGA +AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-LRNEVGVIEYPDGGRYAVAVFTRA +ANATLPAADAVIGTTARMAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. TMED205 TaxID=1986598 RepID=A0A1Z9MLT3_9SYNE +--ALSQRWTQLAAAQDLEASAFLLVLDDGRYA-QMQADRAMPAASSIKTPILLVSLEQID +RGDLRWNEPLTLTKPVVGGGAGWMAKPLGTRFPTYEVATEMIRISDNTATNLLIQRAGGK +ERLNSRFQALGLTATKVNNWLPDLDGT------NTTSARDLSRAIALVDTGGTLSLRTRD +LFRDVMGTSVT-NTLLPKGLMQGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG +PFND-PRSTNLIRAMAAAMA--- +>[subseq from] Beta-lactamase n=1 Tax=Acidomonas methanolica NBRC 104435 TaxID=1231351 RepID=A0A023D884_ACIMT +---LQDEVARLTEGQPGTFAVYAARLGRAPEV-CLKCDEPINAASTMKLFVLDAAYVAFR +AGTLNPDEMIVVHNRSLVGTRDFSYAEVGKPVSVTELLRVMIQYSSNLATNLMVERL-GV +PFIRSVVAHQGLKGITFGRMIEDFDAD-AQGIRNRVTARGLGDFMQKLAQDRIVDPAASE +AMIAILLGQTF-NNVISPGLPPGTPVAHKTGWVT-GVRNDAAIVFPPDGRTYILVELSRD +LP-DDAAGLKRLNAISAAIYAGf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. IBTA2 TaxID=2283625 RepID=UPI00103DB36B +----ERTIRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD +AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GS +DAVDGMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETALLLRAIWTDEAASPESCA +FMRAAMGTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A5K8BQM6_ALCXX +-qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNAATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDTAA-REAGRDNFTSADDATAALCWMLRDGMLPSPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Uncharacterized protein n=1 Tax=Rhodococcus erythropolis TaxID=1833 RepID=A0A5N5E563_RHOER +-----ASIADVCDDANATVAFHVRSLDGKLEI-GSGADARSVTASTYKVPVMLEVAAQAS +EGRIQLADRIKVPADRRTIPSGISAMTDDVEVSIRDLGLLMMQVSDNTATDILQEMV-GT +ENIMSRLRSLGLNSTDITTDCEGIISSLNARGGNTSTPREMTELLSLIWTDKAADAEACA +EVRRVMGLQFA-PHRLSSAYVDGPTISGKTGTFLAGVRNEVGVVDFGDGDVYVVAIFLKD +KNNHMRKVDAAIGKIAALAI--- +>[subseq from] Beta-lactamase n=1 Tax=Kibdelosporangium sp. MJ126-NF4 TaxID=703222 RepID=A0A0K3BB93_9PSEU +------------RDAGTAGWLHAIQLGTGRQV-DVDADEPVVMASVYKLPLLVALCRQFD +AGRIDPLSTVRINPASCTPPTGISTFLDPITMSWRDLAASMMIVSDSAAADVILGEV-GL +DVVQRTLLELELSGTRIVGGTADVSAAYDPAYTSATTPRDMTRLLALIWSDSVASDEQCA +FIRQLMGKQVW-SHRIRTGFPGDVQVSGKTGTIG-AVRNEVAVVEYSGELPIAVAVFTFA +ARADLPAVDTAIGDAARIAV--- +>[subseq from] Beta-lactamase class A n=2 Tax=unclassified Rhodococcus TaxID=192944 RepID=A0A4V3FZ68_9NOCA +-----ASIADVCDDANATVAFHVRSLDGKLEI-GSGADARSVTASTYKVPVMLEVAAQAS +EGRIQLADRIKVPADRRTIPSGISAMTDDVEVSIRDLGLLMMQVSDNTATDILQEMV-GT +KNIMSRLRSLGLNSTDITTDCEGIISSLNARGGNTSTPREMTELLSLIWTDKAADAEACA +EVRRVMGLQFA-PHRLSSAYVDGPTISGKTGTFLAGVRNEVGVVDFGDGDVYVVAIFLKD +KNNHMRKVDAAIGKIAALAI--- +>[subseq from] serine hydrolase n=1 Tax=Dyadobacter bucti TaxID=2572203 RepID=UPI001107F45D +-eKLTAKIEKALAGFKGEAGVYVRNLKTNRVA-AVYADTLFPTASMIKVPIMCGLFDKIN +QGEIKFGQELVYRDSLKYDNGVVGSFRDSTKIPLPKVIHLMISLSDNTGSLWLQAMAGGG +AAINQWLENNGFANTKVNSRTPGRKQGQATYGWGQTTPREMAELVAMIRDGKAISPSVSE +RMYRYLGMQFW-DGEAISQIPPYVKTAAKSGAVNQ-AKSEVLVVHAPHGD-YVFCITTKN +QQQRENEGYMLIRKISEIIWNHf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CB02923 TaxID=1718985 RepID=A0A1Q4W470_9ACTN +------RIRAAFADAGVTGRLHARDIDSGTEV-GAGADHPVVTASVHKLCLLVALHRHAA +NGHLDLAEQSECPPGNRTPPTGIAAMLDPVRMSLRDMAYLMMAVSDHAAADLLLERV-GL +DGVNHITRQLGLTRTHATHTFGQLLAALDPARTNRSTPRDMTRLLGAIWRDEACTAEHDA +AIRRLLGLQVW-PHRLASGFPDDVQVAGKTGSLPT-VRNEVGVIEYPDGGRYAVGVFTRA +ASATLPAADAVIGTAARIAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. AmelKG-D3 TaxID=1115568 RepID=A0A1C6MSX9_9ACTN +-----RTVRSLFDDAGVRGWLHVAELERSARV-VLDPDEPVPMGSVYKIALMAAFCRLAD +AGRLDPCHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLREV-GT +DTVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDRAASPASCA +FMRAAMGTQPW-AHRLASGFPDDVAVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia pseudobrasiliensis TaxID=45979 RepID=UPI0009EE3BFE +----------------------ARCLDCGAET-GWRADEPVVLSSVVKVPLVLELARQIA +AGQLDPTDRVRATAADRLGGPGTSGCRDDVEYSLRDAAYLALSVSDNTAADLLFDRV-GL +DNVRSRVHELGLTRTRVVGALRDLLIIMDPGRTSASTPREMTRLLELIARDEAGPPAACA +WLRELMGAQLN-QARLGSAFGDEVTLWSKTGTLP-GVRNEIGVVRSPDGTRCAVAVFTRA +AVDRAPRVDRAIGAAARAAIE-- +>[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535Y5I6_9CHLR +------------------------------------------------------------ +------------------------------------EVGAMIAVSDNSAANQIVDAI-HP +QAVNDTLARLGLGGTHFMNLFSDARSA-ASPGLNQTTPANMAHLLELIATDQIVSPQVSA +DIRTLLARNVD-RSKLVRLLPPDARVEHKSGWYE-GVANDAGIVTVDRVTRWVIAVFSEN +LP-DAETGNQLVAAISKAVYDAw +>[subseq from] serine hydrolase n=1 Tax=Bacillus mesophilum TaxID=1071718 RepID=UPI00124F3DE7 +--QFNRDVQRLTSAAHGRVSLFIES--DKGVI-EKESHTVYPAASTIKVPILLEALQQAE +SGGIDLKQSISISPSHITGGAGILQSSLPAEMKLVDLLSLMIVVSDNSATNILIDLL-GQ +NQIEQCIKSMNLQETKLQRKMMDFEAG-RRGFENTTSAYDLGICLKFLTEDGLLNEESRA +LGLEIMGRQQL-RKLAYSVSSSEITVYGKTGELP-GVSHDCAILKKDHH-LLYGVVLMDG +IT-QAEEA--------------- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RBG_16_37_8 TaxID=1798371 RepID=A0A1F5YVM1_9BACT +-eEIKSKIEKELAQAEGTYSIYFYDLTTGDNF-GINDNMMLMAASVNKIPILAASYYFAG +KGVIDLDKIIVPQTKDIQDTGSIRYDKPGTAYSIRTLARLMMEKSDNTAAYLLASVIVGL +DEVQKLVTDWGMLQTDMK--------------ENKTSVKDISKVLKKMYQGEITSPELSR +EMLDFMDDSDY-EDRIPKGVPSTITVYHKTGDEVR-TIHDAGIIVLPDR-PYYLGIMTTD +VA-DAEVTKSKMARISQIVFS-- +>[subseq from] serine hydrolase n=1 Tax=Cytophagales bacterium B6 TaxID=100480 RepID=UPI0003B36DF6 +-hKLAVKLQDAVKGFRGQIGIYVQNLKTGKTA-EINADTLFPTASMIKVSIQCGVMDKIE +KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDIQLSKVAMLMITMSDNTASLWLQKLV-GG +QYINNWLEQNGFKVMRVNSRVPGREAIRKIYGWGVTTPREMCRLFTLIREAKAVSAAASE +RMYRNMGRIYW-DEDALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH +NTTPNNEAGLLIKKVSALLWHYf +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=A0A330LHK3_LACSK +------------------------------SVtNWEPAKSQFSASTIKLFILIRYYQLCQ +SGQLNPDDTYVLQKKDMVQGSGTMNDPVGTKYTLQELCNLMIEQSDNIATNVLIDEVGGF +SAVNRTITSVVKHQSSLERKMMDTS-NIENGRANRINAKEAAQTLLQLYQGKVIDPTTDA +QMLSLMLKTKN-RTKLPSQLPAGAICYNKSGESNRGIENDMALIKYNGH-VFAMCVLIEM +DGEGETPIDATIEQT-------- +>[subseq from] Beta-lactamase class A n=1 Tax=Dethiosulfovibrio salsuginis TaxID=561720 RepID=A0A1X7KZL2_9BACT +-------------GIGATAGVVVFAPGLGFRW-SHNDSRRFPAASLIKLAVLWSLFKGDE +AGFWSLQDEMDIPKDHVVEGGLLHRWSHGGRLRLDDLALLMIAVSDNTAANLLIDYI-GM +ERINEDISSLGLRETVLGRKMMDFEAK-KMGMDNYTSPRDLEKLIEALALTG--KPSTRE +RALEMMSCQKL-RSKLPGSIPLEIIVAHKTGELP-GSEHDCGVFFHRGENPVIVVVLTEG +IG-SPEHGVAFCSDIGKKIYVKf +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI0003A16670 +----RERIEAVFADAGAEGFLHAREIGPGPEV-SAGGDDPVVLASVFKIPVALAYAREVA +AGRLDDTERTKVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVLYHRL-GQ +ETVDRVLNDLGLERTRLIGCCEDLFAVRDPERTTSSTPREITELLEAIWTDRAGEPEACE +RVRTIMAQQIW-PHRLSSGFPSGVAIAAKTGTLP-GIRNEAGVVTLGDGRRFAVAVFTRA +HSDRLPAVDASIGAAARLAVDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudokineococcus lusitanus TaxID=763993 RepID=A0A3N1GA01_9ACTN +-------------------------------V-VLGSTESYSSASLIKVALVVAVLRAVD +RGDLALDDTVEVTNSDDVPGTGVLAGYSSPYATIGELCGLAITVSDNTASNVLAEEV-GL +EEVDRLVEDLGLEPTHMGRLFF---SDGPKDESNDLDAASTLELLRAVHDDDVLAPASRG +RLLGWMRQQEL-DTKIAEEVEDDVQTATKTGDTSR-VSHAGGYLLDPGRE-TALVVLTET +EDSPTAAADPYIQDVAALVAE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. ScaeMP-e83 TaxID=1758151 RepID=A0A1C4KHY3_9ACTN +----EAAIRALFDDAGVRGWLHVAELERSARV-VIDPDEQVPMGSVYKVPLMTAFWRLAD +AGRVDPLHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA +DVVDGVCAELGLPHTRIHGGVVGTFDVYDPAYKASSTPAEIARLLRAIWTDEAASPESCS +FMRAAMGTQPW-THRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA +ARADLPRADAVIGAVARVAVE-- +>[subseq from] serine hydrolase n=1 Tax=Acetobacter malorum TaxID=178901 RepID=UPI000A3A262D +---LAQIMAETVKNQPGHFAVYAARSGQPPDV-CLNCDDLINAASTIKLFVLDAAYDAFT +KGTLHPEDTLTVHNHSLVGGSFALYAQAGKAVLVSELLRVMIQYSSNLATNLMIEKL-GV +LPIRAIVKAQGLNGVVFGRMIEDFDAN-DQGIRNRVSARGLGAFLQKLDNGQIVGKTQSQ +SMIQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVQ-GVRNDAALVTLPDGKRYILVVLTSG +LP-DEQAGIRVLNTLSHQAYAYf +>[subseq from] hypothetical protein n=1 Tax=Caldanaerobius polysaccharolyticus TaxID=44256 RepID=UPI00068D4A06 +-nALKAKLQSYISTRPGQISVYVHDLTTGQTL-SIGGDNVYAAASTIKLPLVLYLYEQAA +AGKIDLNTKLTYTPKYYMQGTGILQGQPFGGYTIRELSRLAIEYSDNVAWQMLLDYA-GQ +DNLTAFEKSLGANATGLVNGLS------------VTTPKDMDIYLSELLAFRDENYDLGN +EVLYYMEHSIF-SEGIPQELPSGVVVAHKMGALDD-KFHDVGIVFG--NRPYIITIFTEN +GWED--ASLQTLADISRIVYDY- +>[subseq from] Beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A5K8C7B9_ALCXX +-qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNAATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPSPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Beta-lactamase class A n=2 Tax=Williamsia marianensis TaxID=322609 RepID=A0A315S0K9_9NOCA +----SRQMAEVFADAGCAGWVHARTIGRGREF-GWAADDPVVMASVYKLPLLLAMCDLAE +IGQIDLTATVIVDPADWAVPTGIATLHDPVTLSWRDLAVQMMVISDNAAADVILDRV-GL +PRVQDKLDALGLTETRVVGGMAELQQAYDPALASATTPRDATRLLQLIWTDQAVSAQMSE +FVRSTMRKQAW-QQRLSSGFPLGVTIAGKTGTLG-AIRNEIAVVEYPGEHPIAVAVFTLA +ARLSLPTVEAAVGRAARIAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis australiensis TaxID=546364 RepID=A0A1K1RJ50_9PSEU +---------EIFAAAGVRGFLHARRLGSEASV-EVGADTPVVLASVVKVPLALEFARQVA +AGLLDPADRVHATAADRLGGTGSAGFADDVSYSLRDAALLALSVSDNTAADLLFDRV-GV +ENVRSLLAELGLSRTSIIGAPRDVLRALDPSRTSSTTPRDMTRLLAAIWA----DPGPGA +RVRGWMAAQVS-WHRLTAGFPPEVAVAGKTGTMP-GIRNEIGIATYPDGAAYAVAVFTVG +GAETRPDIDRAIGDAARAAVDQ- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFCSPHIGHO2_01_FULL_39_10 TaxID=1798375 RepID=A0A1F5ZRR8_9BACT +-eTLTKEIKEIIENGGGSYSILAYRYKDGRSI-EINESMQVTAASVNKIPILATLYAMAS +NGEIDIDRQVKLQEDDVQDTGSIRYDPIGTLYSLKTLARLMMEKSDNTAAHILGKIILKE +DKVQEYVDSWGMTQTSMK--------------DNKTSASDMKILLSKIYDGEIANPALSS +EMLDFLHGSDF-EDRIPQDLPTGTKVYHKTGDET-GKIHDVGIVDITDNT-YYIGILTID +MK-DEKKTKKNIAKISQLIYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Rhodococcus sp. 06-469-3-2 TaxID=2022510 RepID=A0A259Y3X1_9NOCA +--TTDEQLRAVFADAGCRGWVRAERIDGTGTVvDYEGDDPVVAASVWKIVLLVAVARAFD +EGSLTATDSVRLVPAQCSPPTGIASFADPVTMSWRDIARSMITVSDNAAADALLGAV-GL +DAVARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSVWLGTAASPAQCR +YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA +ARMDLPLVDQAIGHAARIAV--- +>[subseq from] serine hydrolase n=1 Tax=Lacrimispora indolis TaxID=69825 RepID=UPI00045E8AA2 +--TLEKRIEAEVMSYDGKMGIYLDDF-HGNVI-AVHPDEAFETASAIKTYILACLFDEVE +KGNKSLEDMIEYKEEHVVEGSGVLTAEPGARLRVKDAATFMIIVSDNIATNMIIDYL-GL +DTINRCIKALGCRDTVLYNPIH-FER---YDRLGTSTPRDYAGIFTRLAKGELISRTADE +KMLEIFKKQHY-NSMITKDFPPFITVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE +FSDAAHPATVFGARVSRMILDQf +>[subseq from] serine hydrolase n=1 Tax=Nocardia ninae TaxID=356145 RepID=UPI0011BF8C2C +-------VQEIFRDVGVQGWVHARCFDCGAEV-GSGADEPVVLASVVKVPLVLEFARQVA +AGQLDPTDRVRAGALDRLGGVGTAGCHDDVDLSLRDAAFFAITLSDNTAADLLFERV-GI +DNVRSLVRELGLAGTRIVGAPRHIVQALDPQRTTASTPREMTRLLTLIGEDRAGSAEACR +WVRDLMRQQLN-WHRLAAAFPPEVGVWAKTGTLP-GVRNEIGVLEYPDGSRYAVAVFTRA +GTQRLPEVDRAIGAAAAHAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Echinicola strongylocentroti TaxID=1795355 RepID=A0A2Z4INA7_9BACT +--KLLAGLNVLMEDFEGTAGVYVEHLPSGKFA-AINADTVFPTASIVKIPILVGVFDKIE +KGVLSYHEPLVYRDSLKYGGSGLMQFFDDSTTDLSTLLALMITYSDNTTSLWNQALAGGG +ETINPIMDKYGMEFTRVNSRTQGRKENWEKYGWGQTTPREMATLLKKIRKGEIISPAASE +RMYRLMTNVYY-DDYALSQIPPYIQTAAKQGMVN-ASRSELVMVNAPHGD-YVFYIATKN +NKEPDNASWVLAREVSAFLWQYf +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces misionensis TaxID=67331 RepID=A0A1H4MGS9_9ACTN +---IEETIAEVFAAGGCRGSLCALEVDGPGRV-SVAGGEPAVAASTFKIAVGLEFFCQAA +QGELDPAERVVVSPAGATPGQGLCITEDPVEISLRDVARLMLTISDNTAADVLIRRV-GI +ERIRARLTGLGLTGFHLPGTIHELDTGMRPGRISSATADDLAALLRVVWRDEAGPAQACA +QLRRTMGQQRL-TRKIAAGFGPEVLVASKSGTVPGGVSNDVGVVAFPDGRRYAVAVLTRS +LTPGAPTREDVLGTAARVALDH- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 04182 TaxID=2203198 RepID=A0A429F0V6_9PSEU +--RIADEIEAVFAAAGARGLVHAREVGDGPEV-AVGADDPVVLASVFKIPVALAYAREVV +AGRLDETERTRVIARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDLVYRRI-GQ +EAVDRVLADLGLTRTRLIGCCEDLFAVLDPERTTASTPREITALLDAIWTDRAGDPAACE +RVRKIMAQQIW-PHRMSSGFPAGVAVAAKTGTLP-AVRNEAGVVSDVDGRRYAVAVFTRA +ESDRLPAVDASIGTAARLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora alkaliphila TaxID=1783498 RepID=UPI0013BB5719 +---LSTQIREVAERAGCSLALHVRSLDDDAEV-DIGADTPSLAASTYKVAVLLELACQAA +EGRLDLTGRLRVTPAQHSAISGISTMLDEIEISIRDLALLMIQVSDNTATDVLQRLV-GT +ENIAHRLRNLGIKHTEIRTDCAGLIGESGFRTGNTTTPRDMTRLLQAIWLNQAGPAEACA +EVRRIMSLQFA-PHRISTSYRDGPAIAGKTGTFYGGIRNEVGVLEFGPEDRYAVAVYLRQ +RHYDDGTADAAIGTVTRMAVDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1G7WDM0_SELRU +--SLAQVVTALSNSDSTQYALFVAYPGENREE-YSYQSKQMRSASMIKVFILGTAMEKVR +DGQLSLYQNLVLHSYDKVGGAGVLAGYASGTLTLDTVMRLMITESDNTATNMMIDLL-GM +EEINAYITRNGYGDTILQRKMMDSQAV-AEGRENYTSVNDLGHFFLKLYHRNCVSPELDD +VMLGYLEAQTD-TECFPAALP-GVMICHKTGELY-GLYDDGGIVYQPGR-HFIIVGMTEN +YS-SRGRAISILRQMAKAAAN-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces qinzhouensis TaxID=2599401 RepID=A0A5B8JA55_9ACTN +---------AAFAGAGVTGWLHARDIDTDAEV-DAGADRPVVTASVHKLCVLVTLHEAAA +AGRLDLTEQTEIPAHGRTPGPTGLGAMLDGALSLRDAAFLMMSVSDNAAADVLLERV-GL +DAVNATTRRLGMPRTEAVETFGSFLGALDPARTNRSTPRDMTALLAAVWRDEAGTPEHCA +AMRRILGLQVW-PHRLASGFPDDVQVAGKTGSVPT-LRNEVGVVAYPDGGRYAVAVFTRA +ASATLPAADAVIGTAARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis kentuckyensis TaxID=218823 RepID=UPI00142DF7CD +--AVEAEIAEVFADAGARGFLHAREIGGGPSV-AVGADDPVVLASVFKILVAVAYAREAA +AGRLDETARTRVGPRYRIGGIGTAGCADDVEMSWRDLALVMLTMSDNAATDVVYHRI-GA +AAVDRVPADLGLHRTRLIGCCEDLFAVLDPERTTSSTPREITELLDAVWTDRAGDPAACE +RVRSMLARQIW-PHRLSSGFPSDVGVAAKTGTLPS-VRNEAGVVSYPDGRRFAVAVFTRA +NSDRQPAIDAAIGRAGRLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. A23 TaxID=2606593 RepID=UPI0012D74D33 +---------------------HAREIGGGPEV-AVGADDPVVLASVFKIPVAVAYAREVV +AGRLDETGRTRVGKRYRIGGIGTAGCADDVEMSWRDLALVMLTMSDNAATDVLYHRV-GR +EAVDRVLGDLDLSRTRLIGCCEDLFAVLDPERTSASTPREITTLLDAIWTGRAAEPAACE +RVRSMMARQIW-PHRLSSGFPSDVAVAAKTGTLP-AVRNEAGVVSYPDGRRFAVAVFTRA +DSERQPAVDAAIGKAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A651HSB9_9BACT +-tQFQQELEALVSAYEGVGGVHVVDLTDGTRF-AVRDHLIFPQASAIKIPILVELFRQAE +DEPGLRERRVEVTDQVRTAGSGVLQHLTDGGLSLEDHAIYMILYSDNTSTNVLIDEL-GM +DAVNALSASLGAPETRLQRKMIRPEQS-ARGNENLSTPRDAAVIMERIMECDLMSEASCR +RVKEILAIPKGGA--YMDPIPGGVAVPWKPGGIT-GVATAWGAVELPGR-PYVLVVMSSY +GG----DGGAFIRQVSTAAWGYf +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3C1JR78_9CHLR +--DLNSALEAAISGIQGDFAWHIEDPSTGRAW-TRNAHEAYPAASTLKVAVFLRLLQLVD +DGRVGLDHQIRLRRWHQVGGAGVLQYFSPETLTVGEVATLMVILSDNTATNMIIDLT-GL +GAVNNLVSCLASHATRINRYYGKPSMALPDGTHAMATANDLATIYREVLAGKILGPRGRQ +AFWQTLLRQQD-RAMAPRHFGPDILIAHKTGAID-GVRNDVGVFWLPD------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. MYb66 TaxID=1848692 RepID=A0A2S8Z3L2_9MICO +-----------------------IGVEGGPEV-SVGADEPVVLASVFKIPVLTAYVRAVA +AGELDPTERTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDVIYHRV-GA +AAIDRVIADLGLDGTRLIGCCEDLFAAVHPVRTSHSTPRDVTTLLDALWTDAAASAEACR +QARDIMAQQIW-PHRLSSGFPSGVRIAAKTGTLPT-WRNEAGVVTYPDGRRYAVAVFTRA +TSERQPLVDASIGR--------- +>[subseq from] serine hydrolase n=1 Tax=Kitasatospora aureofaciens TaxID=1894 RepID=UPI000995FDF4 +--AARARIAAAFAEAGVTGLLHARDLDTGAEL-ALGADTPVSTASVHKLCLLVTLYREAT +AGRIDLTRPVDLPATGRTPGRTGLSAMLDAALSLRDLAYLTLAVSDNAAADVLWDEI-GL +DTVNRTMAELGLTRTIAVHTVRELFAVLDPAFTNRSTAREMTALLAALWHGDACPGEPGA +ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA +AATSLPTADAAIGTAARLAVD-- +>[subseq from] Putative beta-lactamase n=2 Tax=Rhodococcus erythropolis TaxID=1833 RepID=C3JVV9_RHOER +-----ASIADVCDDANATVAFHVRSLDGNLEI-GSGADARSVTASTYKVPVMLEVAAQAS +EGRIQLADRIKVPADRRTIPSGISAMTDDVEVSIRDLALLMMQVSDNTATDILQEMV-GT +ENIMSRLRALGLNSTSITTDCEGIISSLNARGGNTSTPREMTELLSLIWTDKAADAEACA +EVRRVMGLQFA-PHRLSSAYVDGPTISGKTGTFLAGVRNEVGVVDFGDEDLYVVAIFLRD +KNNYNSKVDAAIGKIAALAI--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces gardneri TaxID=66892 RepID=A0A4Y3RZJ4_9ACTN +haAARRRITAAFADAGVTGLLHAVDIDTGTAL-GIGSDTLVPTASVHKLCLVATLYRQSS +LGLIDPTRPVEIPAEDRAPGATGLSVMRDAALSLRDLASLAVAVSDNTAADLLWDAL-GL +DTVNATMTGLGLTRTHAVQTMRELFAALDPTRTNRSTPREITALLAAVWRDEVCAGEYGE +ELRALLGLQAW-SHRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA +ASTDLPAADAVIGGAARIAVD-- +>[subseq from] Uncharacterized protein n=2 Tax=Fictibacillus aquaticus TaxID=2021314 RepID=A0A235F5M2_9BACI +---FSEYIKEMVSSFNGNASIMIE---GKMNA-EWNSSLRVRSASLIKLAVMLEVFRQAE +QGSLSLTAPIKVSSHCMTGGSGVLKTEVDRTFSILELVTLMITVSDNSATNKLIDLI-GI +NRINSFCKDIGCCETVIQRRMMDLHS----DKDNWTSARDTVTMLKQILRS-----PFQN +EMLSILCSQQF-RHKLPALMNPCLAVGSKTGELP-GLEHDAAIIVKDEGEPVIAAVLLSD +FKNS-NDAIMLHRN--------- +>[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium sp. HMSC073F01 TaxID=1739251 RepID=A0A1E9IK27_9FUSO +-eKFEKKLLEILKKYNKKYGIIIKSLESEFFL-KVGNMEAYPAASLIKLPILYELFNNSK +---YNLDEKIEITLKDKVGGFGIIQYHNNVKLSLRDLAILMIILSDNTATNILIDIC-GM +DNINFTLKKLGLKDTKLRRKMMDLKSK-NMGLDNYTSPYDMVKLLEVLNK--------NE +EIISIMKKQLC-NNKISHFIEKKIDFAHKTGDLPQ-IEHDVGIFDIEDKK-IIVVVMTKN +FENR--DEIELNNKVGEFI---- +>[subseq from] Serine hydrolase n=1 Tax=Kribbella sp. 16K104 TaxID=2530375 RepID=A0A4R4XGG7_9ACTN +----NARIRAVFEDAGVRGWLHAVAFDSPSDTvEVDADGVVPMASVYKLPLLAGFCRLVD +LGELDPLERLTLDPSERTAGPTGLSVLADPVMSLRDLAVSMMTVSDNASADALLGLV-GL +RRLADLLESFGLHRTWVRRGTAANLRVYEAANASASTPRDMTLLLRRLWAGELLSAGQTE +FVQATMHRQIF-QHRMASGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGAAFAIAVFTLA +ARGDQPRVDAAIGEAARAAVD-- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006BECE9F +-qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDTAA-REAGRDNFTSADDATAALCWMLRDGMLPSPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0007614061 +-qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDTAA-REAGRDNFTSADDATAALCWMLRDGMLPSPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RBG_16_52_11 TaxID=1798374 RepID=A0A1F5YMI2_9BACT +--ELENSIRQAVGNAWKNYSVVVEDMNSSFTV-SIDGMVMHRAASVNKVPILAALYVLSE +RGETDLNRVITLQAGDIQNTGSIRYDSPGSTYSVKTLAKLMIQKSDNTAAYILAQYIVGQ +QRLKKMVSDFGLVQTDMDE--------------NTTSNADMAKLFRKIYRNELTNQAYSG +EMLAFLKDSDF-EDRLPGKLPPGTTIYHKIGTEV-GNIHDVGIVETPDGA-FYIGVLTSD +VT-DETQATELIAMISRLVYD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL F-3213 TaxID=1463846 RepID=UPI000566C571 +---ASETIARRAEEVGVEVRLHAAEVDGTRSL-GIGEDVPVVPASVFKVPIALELARQAA +EGTLDLGAPVTVEPGHPTPPYGLATFRHEVRMSWHDLAILMIGISDNVATDLILAEV-GK +DAVNSTLRRLGFTQTVVPQDCGELLAALQPEKSCRTTAAEMTRLLGLIWRGEAAAPEACA +DVRRWMELQVW-PHRLRSGFPDGIRTSGKTGTLP-AVRNEVGVVEYPDGGRYSVAVFTRA +EDSRVPERDALIGFAAATAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Lactobacillus paraplantarum TaxID=60520 RepID=A0A512FIW8_9LACO +---VSELVEQTMQDVAGRTSIAVMPLTGSQTV--IVNNGAQRAGSLITLFILVTAYDQVH +QNNWQMQNRYTLRAEDKVGGTGTLHTLPAGSLTYAEIAKRMITDSDNTAANIMLDRVGGV +SAINSEVAQLDLKDTTMARRLMDTA-ALKAGRDNYTSVRDVATILQRLANYRLISKRVDQ +AMLTILKANTD-HSKLVKNLPKRATIYNKTGDYQYGVQNDAAIVKNRQGT-FIMTVMAAD +GEREA--QTTALN---------- +>[subseq from] serine hydrolase n=1 Tax=Nocardia arthritidis TaxID=228602 RepID=UPI00142D72A1 +---------------GVRGWVHARCLGCGGEV-GVGADELVVLSSVVKLPLVVEFARQVA +AGQVDPRDRVRAEAADRLGGAGTSGCADDVELSLRDAALFALSVSDSTAADLLFDRV-GL +DNVRSLMRELGLVRTRIVGALRDLVLVYDPARTTASTPREMTRLLELIARDEAGPPQACR +MVRELMGHQVN-QQRLPAAFPADVAVWSKTGTLP-GVRNEIGVVEFPDETRYAVAVFTRA +QTLDRPDVDRVIGSAAAAAI--- +>[subseq from] Serine hydrolase n=1 Tax=Runella sp. SP2 TaxID=2268026 RepID=A0A3G3GK38_9BACT +-kKLTALLQELIKGHEGDVGVYVRNLKTNKIV-EINADTLFPTASMIKVPIQCGLFDKIS +KGELKYNAILTYKDSLHYDDGIVGSLKDGAKIPLSEVVMLMETVSDNTGSLWCQALAGGG +KSINEWLDKNGFTATRVNSRTPGREANRTRYGWGQTSPREMAELIAMIRAGKAISPDASD +RMYRNLTRQYWDGEGL-SQLPPEIKTACKNGAVNR-SRSEAVLVHAPHGE-YVYCVITKN +NKTSNNAGYVLLRKVAKALWNYy +>[subseq from] serine hydrolase n=1 Tax=Streptomyces gardneri TaxID=66892 RepID=UPI0011430817 +haAARRRITAAFADAGVTGLLHAVDIDTGTAL-GIGSDTLVPTASVHKLCLVATLYRQSS +LGLIDPTRPVEIPAEDRAPGATGLSVMRDAALSLRDLASLAVAVSDNTAADLLWDAL-GL +DTVNATMTGLGLTRTHAVQTMRELFAALDPTRTNRSTPREITALLAAVWRDEVCAGEYGE +ELRALLGLQAW-SHRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA +ASTDLPAADAVIGGAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3L7YUG6_9CHLR +--DLNSALEAAISGIQGDFAWHIEDPSTGRAW-TRNAHEAYPAASTLKVAVFLRLLQLVD +DGRVGLDHQIRLRRWHQVGGAGVLQYFSPETLTVGEVATLMVILSDNTATNMIIDLT-GL +GSVNNLVTSLASRVTRINRYYGKPSMALPDGTHAMATANDLATVYREVLAGKILGPIGRQ +AFWQTLLRQQD-RAMAPRHFGPDILIAHKTGAID-GVRNDVGVFWLPD------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Cyanobium usitatum str. Tous TaxID=2116684 RepID=A0A2P7N221_9CYAN +-----KRWSELAAQKGLTASAFLLVLDDGRFA-QLQPDLPLPAASSIKTPILLAGLEDLD +NGKLRWNEPLPLTKEVMGGGAGWMAKPVGTRFPFFEAATEMIRVSDNSATNLLIKRLGGK +TTLNERFTAMGLPSTAVNNWLPDLEGT------NTTSSRDLAKSIAMVDIGESLSPRARD +LFREIMGSSRT-NTLIPLGLLQGITVYNKTGDIGI-AYADAALIQLPNGQRAVAAFMVKG +PFND-PRSTDLIRAMAAEV---- +>[subseq from] serine hydrolase n=1 Tax=Legionella tunisiensis TaxID=1034944 RepID=UPI0012EAD828 +------------------------------------------------------------ +--------------------------------------------------------MGGL +EKINDFARSIHNDTFRQDNGWPEAMSGGKNNVYDSSTPKDMAQSLQQLTLNSVLANPQHE +LLLSWLKSNTTGDNRIRAGVPKSWLVGDKTGTGMYGTTNDIGIIWPPQCAPIVMAVYYTN +NNKEAVKREDIVSSVTRLVIDGf +>[subseq from] Serine hydrolase n=1 Tax=Cyanobium sp. TaxID=2164130 RepID=A0A4P5VLV2_9CYAN +--ALSQEWARLAAAQGLTASGFLLVLDDGRYA-QLKSDLPMPAASSIKSPILLVGLDELD +RGKVRWNEPLPLTKDVMGEGAGWMANPLGTRFPFFEAATEMIRVSDNSATNLLIKRLGGI +KMVNQRFQELGLPATVLRNWLPDLKGT------NSTSARDLARTIALVDTGEKLSPRARD +LYREILSTSNT-NTLIPMGLLKGITAYNKTGDIGI-AYADAALIQLPNGQRAVAAFLVKG +PFND-PRSAELIRAMAATVS--- +>[subseq from] Zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus paraplantarum TaxID=60520 RepID=A0A4Q9Y0B7_9LACO +---VSELVEQTMQDVAGRTSIAVMPLTGSQTV--IVNNGAQRAGSLITLFILVTAYDQVH +QNNWQMQDRYTLRAEDKVGGTGTLHTLPAGSLTYAEIAKRMITDSDNTAANIMLDRVGGV +SAINSEVAQLDLKDTTMARRLMDTA-ALKAGRDNYTSVRDVATILQRLANYRLISKRVDQ +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVKNRQGT-FIMTVMAAD +GEREA--QTTALN---------- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006C33E8E +-qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNAATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPSPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FS--------------------- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus paraplantarum TaxID=60520 RepID=UPI0003ADD6A5 +---VSELVEQTMQDVAGRTSIAVMPLTGSQTV--IVNNGAQRAGSLITLFILVTAYDQVH +QNNWQMQDRYTLRAEDKVGGTGTLHTLPAGSLTYAEIAKRMITDSDNTAANIMLDRVGGV +SAINSEVAQLDLKDTTMARRLMDTA-ALKAGRDNYTSVRDVATILQRLANYRLISKRVDQ +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVKNRQGT-FIMTVMAAD +GEREA--QTTALN---------- +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A329U415_9FIRM +--TLEKRIAAELYSYQGKMSVFVDDL-HGHTV-EIGADEEFETASTIKAYILAALYLQAS +RGKASLEEKITYKPEHFVDGSGMLRAGVGASLKVKDAATMMIICSDNIATNMVIDYL-GL +DTINACIREMGFAHTVLHNPLHDLYN-----DLGTTTPRDYASLFAQVAKGTLVSAEASA +EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Jiangella sp. DSM 45060 TaxID=1798224 RepID=A0A1H2ARG2_9ACTN +---VEGELSDAFAAAGVTGFLHAADVGSGAEV-GVEPDAPVVTASVFKIPVLVELCRQFA +TGERAPADRLRVPAGGRTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR +EKINAGMAALGLTGTVLEEDCAGLFRVLDARTTNRSTPRETTTLLRRVWTADGLPEAACD +EIRRILALQVW-PHRLTSGFPDDVRVSGKTGTLSH-VRNEVGVVEYPDGGTYAVAVFLRL +PGPENPAADAVIGTAARIAVDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Thermohydrogenium kirishiense TaxID=937254 RepID=A0A4R4A9X7_9FIRM +-qELKNNIETLLSQHPGKYGVYFIDLNSGETF-DINGYDSFVAASTYKVPLNFYLYTLIT +EGKIDPNMEVQYTSQDYESGSGSIQYDPVGTYTIRELSRRSIEESDNIASNMIMRVV-GY +DNYLNFMKSMGANVIPY--------------TSNITSPRDLSLYMEKLLNYANAHSSTAG +ELLNYLENTIY-NDRISYPLPSNITVAHKIGNLSD-VVNDTAIVFYPSK-PYILTIMGNN +VDSDNSDAYTVIRKISKMVYD-- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006C435AD +-qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPSPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Peptidoglycan-binding protein n=1 Tax=Thermoanaerobacterium thermosaccharolyticum TaxID=1517 RepID=A0A2G1CJJ8_THETR +-qELKNNIETLLSQHPGKYGVYFIDLNSGETF-DINGYDSFVAASTYKVPLNFYLYTLIT +EGKIDPNMEVQYTSQDYESGSGSIQYDPVGTYTIRELSRRSIEESDNIASNMIMRVV-GY +DNYLNFMKSMGANVIPY--------------TSNITSPRDLSLYMEKLLNYANAHSSTAG +ELLNYLENTIY-NDRISYPLPSNITVAHKIGNLSD-VVNDTAIVFYPSK-PYILTIMGNN +VDSDNSDAYTVIRKISKMVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3B9Z1V1_9CHLR +--DLNSALEAAISGIQGDFAWHIEDPSTGRAW-TRNAHEAYPAASTLKVAVFLRLLQLVD +DGRVGLDHQIRLRRWHQVGGAGVLQYFSPETLTVGEVATLMVILSDNTATNMIIDLT-GL +GAVNNLVSCLASHATRINRYYGKPSMALPDGTHAMATANDLATIYREVLAGKILGPRGRQ +AFWQTLLRQQD-RAMAPRHFGPDILIAHKTGAID-GVRNDVGVFWLPD------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Dyadobacter sp. AR-3-6 TaxID=2541721 RepID=A0A4R5E2S6_9BACT +-kKLKTKLEKALSGFHGDVGVYVRNIKTNRTA-AVNADSLFPTASMIKVPILCGIFDKIY +KGEVKFDEELIYRDSLKYDNGIVGSFRDSTKIPLPKVVHLMISLSDNTGSLWLQAMAGGG +STINDWLATNGFTNTRVNSRTPGRKQAQATYGWGQTTPREMAELIAMIRNGKAISPDISE +RMYRYLGMQFW-DGEAISQIPPYIKTAAKSGAVNQ-AKSEALIVHAPHGD-YVFCITTKN +QADQENEGYVLIRKVSEIIWNHf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. WAC 05977 TaxID=2203208 RepID=A0A429BF30_9ACTN +--RIADEIEAVFAAAGARGFLHAREVGSGPEV-AVGADDPVVLASVFKIPVAVAYAREVV +AGRLDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDLVYHRV-GQ +EAVDRVLADLGLARTRLIGCCEDLFAVLDPERTTASTPREITALLDAIWTDRAGDPAACE +RVRKTMAQQIW-PHRISSGFPAGVAIAAKTGTLP-AVRNEAGVVSDVDGRRYAVAVFTRA +ESDRLPAVDASIGTAARLAVDH- +>[subseq from] Peptidoglycan-binding domain 1 protein n=2 Tax=Patescibacteria group TaxID=1783273 RepID=A0A0G1FBL5_9BACT +---LIVQIRNLLVKENGSYSVYLYDLTSNQGY-GINETGIFTAASVNKIPILAAIYFEAE +RGALDLDERITLQQNDIQDYGTGSLDGIGKVYSLKTLAQLMIEKSDNTAAFVLSKIV-GL +KRIQELVENWGLTQTDML--------------ENKTSNKDIAMLMTKMYKNQIANQARTL +EMVGFMDDSDF-ENRLPAQLPEEVVVYHKIGTEV-GNIHDVGIFALANH-PYYLGVMSND +IS-DETRAETVIAEISKLTY--- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium GW2011_GWA2_43_14 TaxID=1618443 RepID=A0A0G1FN63_9BACT +---LEKEIAREVAKTQGTFSVYFYDLESGRNF-GINEQMQVMAASVNKIPILAALYYKVA +KNELDLDRIIVPQAKDIRDGTGSIQDPPGTPYSLKTLARLMMEKSDNTAAYILASLVIGL +DDIQSLVESWGMTQTDML--------------SNKTSARDIGIVTIKMYRGEITNSALTR +EMIDFMDDSDF-EDRIPKGVDSQVKVYHKTGDEVR-TVHDAGIIDLPGK-PYFLAVFATD +VV-DATITKEKIVLISRIIYE-- +>[subseq from] Serine hydrolase n=2 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A1Q6QFD9_9FIRM +--TLEKRIAAELYSYQGKMSVFVDDL-HGHTV-EIGADEEFETASTIKAYILAALYLQAS +RGKASLEEKITYKPEHFVDGSGMLRAGVGASLKVKDAATMMIICSDNIATNMVIDYL-GL +DTINACIREMGFAHTVLHNPL---HFDIYND-LGTTTPRDYASLFAQVAKGTLVSAEASA +EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Streptomyces diastatochromogenes TaxID=42236 RepID=A0A233S184_9ACTN +---IEDKLAQVFAEAGCQGSVAVLDIDGSGQV-VLDGDELVVAASTFKIAVALELFCQGA +EGELDLAERVRLAPSQATPGQGFCIFEDEAEVSLRDLARMMVTISDNTATDVLIRRV-SV +PRIHARLAALGLDRIRLAGTIQEEFDSLRPGHITSATAGQMAALLRMIWRDEAGPAAACA +AVRSVIGQQRL-TRKIATGFGDEVRVAAKSGTVPGCVSNDAGVVHFPDGSRFAVAVFTRP +TGPQTPQADSVIGTVARLCVEH- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CFH S0261 TaxID=1644109 RepID=UPI00106FB35B +----RERIEAVFADAGAEGFLHAREIGPGPEV-SAGGDDPVVLASVFKIPVALAYAREVA +AGRLDDTERTKVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVLYHRL-GQ +ETVDRVLNDLGLERTRLIGCCEDLFAVRDPERTTSSTPREITELLEAIWTDRAGEPEACE +RVRTIMAQQIW-PHRLSSGFPSGVAIAAKTGTLP-GIRNEAGVVTLGDGRRFAVAVFTRA +HSDRLPAVDASIGTAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. SID8362 TaxID=2690346 RepID=A0A6B2DY14_9PSEU +---VETRIADAFLAAGARGFLHAKEIGGGGEV-AVGADDPVVLASVFKIPVAVAYAREVV +AGRLDETERTRVGKRYRIGGIGTAGCADDVELSWRDLALFMLTMSDNAATDVIYHRV-GQ +AAVDRVLADLGLGRTRLIGCCEDLFAVLDPERTTSSTPREITTLLDAIWTDRAGEPAACE +RVRAIMARQIW-PHRISSGFGSDVAIAAKTGTLP-AVRNEAGVLSYPDGRRFAVAVFTRA +DSERQPAVDAAIGKAARLAVDH- +>[subseq from] serine hydrolase n=1 Tax=[Clostridium] methoxybenzovorans TaxID=81424 RepID=UPI0003F85BF6 +--TLEKRIEAEIMSYDGKMGIYLDDF-HGNVI-AVHPDEAFETASAIKTYILACLFDEVE +KGNKSLEDMIEYKEEHVVEGSGVLTAEPGARLRVKDAATFMIIVSDNIATNMIIDYL-GL +DTINRCIKALGCRDTVLYNPIH-FER---YDRLGTSTPRDYVGIFTRLAKGELISRTADE +KMLEIFKKQHY-NSMITKDFPPFITVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE +FSDAAHPATVFGARVSRMILDQf +>[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Thermoanaerobacterium thermosaccharolyticum TaxID=1517 RepID=UPI00123B57B1 +-qELKNNIETLLSQHPGKYGVYFIDLNSGQTF-NINGYDSFVAASTYKVPLNFYLYTLIT +EGKIDPNMEVQYTSQDYESGSGSIQYDPVGTYTIRELSRRSIEESDNIASNMIMRVV-GY +DNYLNFMKSMGANVIPY--------------TSNITSPRDLSLYMENLLNYANAHSSTAG +ELLNYLENTIY-NDRISYPLPSNITVAHKIGNLSD-VVNDTAIVFYPSK-PYILTIMGNN +VDSDNSDAYTVIREISKMVYD-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. C2-6-12 TaxID=2698832 RepID=UPI00136CABE1 +------EIKKYLESRIGTYAFFFEDLESGFTF-GYNENVQMTAAGCMKLLIAVSVIKYVE +DGKGSFLDKIKIEEEDKVYGTGILHEFDNREYTLFELLVAMLIQSDNTAANKLIDIV-GI +DNINKDIEAQGLKNTKLNRKTSDERAA-SNGIENITSSLDLAKIWKNLYNSSFLNEKNST +MLIDILQRQQM-KNKLALYIPDDYEISSKTGDKN-GVENDTALIHLQKG-SFTFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Uncharacterized protein n=1 Tax=Rhodococcus qingshengii TaxID=334542 RepID=A0A069JTK1_9NOCA +-----ASIADVCDDANATVAFHVRSLDGNLEI-GSGADARSVTASTYKVPVMLEVAAQAS +EGRIQLADRIKVPADRRTIPSGISAMTDEVEVSIRDLALLMMQVSDNTATDILQEMV-GT +ENIMSRLRALGLNSTSITTDCEGIISSLNARGGNTSTPREMTELLSLIWTDKAANAEACA +EVRRVMGLQFA-PHRLSSAYVDGPTISGKTGTFLAGVRNEVGVVDFGDEDLYVVAIFLRD +KNNYNSKVDAAIGKIAALAI--- +>[subseq from] Uncharacterized protein n=1 Tax=Acidaminococcus intestini TaxID=187327 RepID=C0WAD9_9FIRM +-dALQKDVEMYLAKRPGKTAVSCWLLTEKQGF-SIGGKNELPSASLIKLLVLVELCEEVR +RGRANLKEAISILGPAITGGDGIIKEKIGHTFTLEELATLMIIVSDNEAANQLIDRL-GM +KAINERAKKLGLAQTHLGRLMMADAS-GEKERDNWTSADDTVHLLRVICETAKTGSPLGR +WMISLLARQQQ-EGGLRRNLPDFVQVAHKCGNLA-GVEHDAGIFFG--KRPYLLAVLTTE +QPASY-VGRETIG---------- +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A2A6ZBD8_9FIRM +--TLEKRIAAELYCYQGKMSVFLDDL-QGHTV-EVGADEEFETASTIKAFLLAALYLQVQ +RGKADLAEEITYEQSQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DIINACIRELGFAHTVLHNPLHF-DR---YRQLGTTTPRDYAALFVRIAKGELVSREASA +EMLSILRQQHY-NTMLTHDFPQYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] Uncharacterized protein n=1 Tax=marine metagenome TaxID=408172 RepID=A0A381X8Z7_9ZZZZ +-----LRVRNIIRAFSGRVGVSARNLTTSEKF-NINEQTVFPALSSIKLAILIELFYQEK +EGKLQLDEKITITRSDQRGGTGILRDLTPPILSLRDLAVLMITVSDNTSTWLVSSKV-GR +SNVNDRMRLLGLKAMDLRSDLPAIFEHTDIDAYAVSSPADMTDLIGLIAEGKVVSRRACT +QMIEILRMCQS-VDFLGRYLPPEAKLANKIGSMMH-GRTDVGLVETESV-RYVITVMTDR +SLMSVHEGTEVIGRISKAVYDAw +>[subseq from] Beta-lactamase n=2 Tax=Synechococcus sp. GFB01 TaxID=1662190 RepID=A0A0J6BIJ8_9SYNE +--ALSQRWTQLAAQKDLTASAFLLVLDDGRFA-QLKPDLPLPAASSIKTPILLVGLDELD +SGRLRWNEPLSLTKEVVGGGAGWMANRPXGTFPFFEAATEMIRVSDNSATNLLIKRLGGK +QKLNQRFLSLGLSATVVNNWLPDLDGT------NTTSSRDLARSIALVDTGQKLGPRARD +LFREIMGTSRT-NTLIPRGLLQGITVYNKTGDIGI-AYADAGLIQLPNGQRAVAAFMVKG +PFND-PRSTDLIRAMAAEV---- +>[subseq from] Uncharacterized protein n=1 Tax=Acetobacter nitrogenifigens DSM 23921 = LMG 23498 TaxID=1120919 RepID=A0A511XEK3_9PROT +--TLAESISKITAGQPGYFSVYAARSGQSPSA-CLNCDEPINAASTIKLFVLDAAYVAFH +EGALKPDETIIVHNRSLVGTGNFAYAQAGKPVSVAELLRVMIQYSSNLATNLMIERL-GV +MPIRAVVSQQGLDGITFGRMIEDFDAD-RQGIRNRVSARGLGNFLQKLDHGEIVGAPESH +AMIDIMLGQKF-NDIIPPGLPTHTPVAHKTGWVN-GVRNDAAIVFLPSGRHFILVELSRD +LP-NESEGIKVMNRISEVVFAAf +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Microgenomates bacterium TaxID=2093373 RepID=A0A3A4ZMQ0_9BACT +---TETRVQAITKSLSGVYGVYVYDLNAGYAY-GQEEDEVFEAASLIKLPVMAMMYSEAE +NGNLNLNRVYTLKDSDKIGGSGSLYYEPAGTLSLRDLVWKMGQESDNTAFNIARNML-GD +SEIEAYMKNIGMTHTSLKNN--------------ETTPRDMGIFFKKLWEMKLVEEGGRD +EILNSLTGTIY-ENWLPSGLPDSLVVAHKFGREVN-VVNDAGIVFAN--SPYIIVVLSKG +VI--YKEADSALPEISRTVF--- +>[subseq from] serine hydrolase n=1 Tax=Achromobacter denitrificans TaxID=32002 RepID=UPI000743036F +-qHVDAALTPLLAATPARVSLSLRDLDGGVVL-ARHADRVQPSASIIKVPILLALLEAVA +NGRYALEQSLALPASDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWNQRANLEATRLQRRMMDAAA-REAGRDNYTSAGDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVALAVLADG +FT--------------------- +>[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora halotolerans TaxID=1981512 RepID=UPI0013D0E8E4 +----ERKIQQCFDDAGGHLHAVALH-DRHREI-GVLPDEPVVLASVFKLPLMIAFAQMVD +AGELDPTELTTLTPDVRSPPTGFAAMADPVTVSWRDIARSMMTVSDNTAADALLSVV-GL +ERVRTALAGLGARSTRVVGGIRDLYDDPANPHNNVGTCRDMLLLLEAVWQDRAASAEQCA +FIRGVMAQQVW-TQRLSAGFPDDVVVSGKTGTFV-ALRHEAGVVEYPNGESYAVAVFTLS +TRLVLPAADAAIAQAARLAVA-- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CA-128772 TaxID=2073159 RepID=UPI000CD15747 +--------------VGVRGFLHARRLGSSGET-GLDADEPVVLASVVKVPLAFEFARQMA +AGLLDPADRVRATAADRLGGTGSAGFADDAEYSLRDAARLALSVSDNTAADLLFDRV-GV +DNVRSLLAELGLTRTSVMGAPRDVLRALDPLRTSATTPREMTTLLAAIWAADAAAP---- +-VREWMSAQVS-WHRLTAGFPPEVAVAGKTGTMP-GIRNEIGVATYPDGTAYAVAVFTTG +GAETRPDIDRAIGEAARTAVDQ- +>[subseq from] Beta-lactamase n=1 Tax=Acidaminococcus intestini (strain RyC-MR95) TaxID=568816 RepID=G4Q913_ACIIR +-dALQKDVEMYLAKRPGKTAVSCWLLTEKQGF-SIGGKNELPSASLIKLLVLVELCEEVR +RGRANLKEAISILGPAITGGDGIIKEKIGHTFTLEELATLMIIVSDNEAANQLIDRL-GM +KAINERAKKLGLAQTHLGRLMMADAS-GEKERDNWTSADDTVHLLRVICETAKTGSPLGR +WMISLLARQQQ-EGGLRRNLPDFVQVAHKCGNLA-GVEHDAGIFFG--KRPYLLAVLTTE +QPASY-VGRETIG---------- +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. NEAU-Ht49 TaxID=2483351 RepID=A0A3M2LTS5_9ACTN +-----AAIERAFADAGVAGHLHAVDVDTGREL-GVGADEPVVLASVYKVPLLVAFFRLAA +RGALDPAERITLCPAERTEGTGLSVMLDDVTMSLRDLACLMITVSDNAAADAVYARV-GR +DEIGAALGALGLTRVHVTGDGRDLFASLDPSRTSDGTPRELTRLLSMIWRDEAAPAPECA +QMRRLLGLQVW-PHRLSSGFPDDVRVSGKTGTLLT-VRNEIGVVEYPDGGRYAVAVFTRA +AEAVAPRADAVIGTAARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Selenomonas sp. ND2010 TaxID=1410618 RepID=UPI00068C90BA +--ELNRNIERILGGDSARYAIYFLRPAEEEEP-FLYQNRPMSPASMIKVFIMAAVMQEVH +DGRLSLEEKLVIRESDVVGGAGVITWNIGEVRSIRELVSGMIMSSDNTATNILIDRL-GM +DKINRYIQEHGYGDTQLVHKMMIGN----GGRKNFSSARDLGKLFSRLYYHQLVGESEDR +FMELVLSGQKD-KECFNAALP-DFTIAHKTGEVT-GLYDDGGIFYGKQGD-FVLVIMNEG +FT--------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis vancoresmycina DSM 44592 TaxID=1292037 RepID=R1I0L2_9PSEU +---------AFFEAVGVRGFLHARRLGTADSL-GLAADSPVVLASVVKVPLAYEFARQVA +AGQLDPADRVHASAADRLGGTGSAGFADDVSYSLRDAALLALTVSDNTAADLLFDRV-GV +DNVRSLLAELGLTRTTVVGAPRDLLRALDPLRTSATTPREMTTLLSAIWADDVGAP---- +-VREWMSAQVS-WHRLTAGFPPEVAVAGKTGTMP-GIRNEIGVATYPDGAAYAVAVFTAG +GAETRPDIDRAIGAAARAAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFCSPLOWO2_01_FULL_46_9 TaxID=1798394 RepID=A0A1F6AXP2_9BACT +---LQDKIKQRIGNAWDNYSILVIDYNSPFVL-GINESTIYAAASINKVPILAAIYDKAQ +RGQVDFDKVITVQKEDIQDTGSIRYDPPGSTYSIKTLVRLMMQKSDNTAAFLLANYIIGL +SAVQSYINQNGLTQTDMV--------------KNKTSNKDMAILFEKIYRRKITNPALSD +EMLGFMADSDF-EDRLPGLLPKGTKVFHKIGTGT-GAVHDVGVVEHGKT-VYYIGMFTSD +VG-DEEQAAKLVAEVSREIFD-- +>[subseq from] Serine hydrolase n=1 Tax=Pedobacter sp. TaxID=1411316 RepID=A0A520ACT8_9SPHI +-kSLQKKLNELVQGFNGDVGIYVKNLKTGKTA-SINADTIFPTASMIKVPITCGIFNKIE +KGELDYHSELMYCDSLLYAGEDILGSFKDSEIALNKVLMLMITTSDNTASLWAQLLAGTG +TSINDVMASNCLKDTRVNSRTPGRKDNQRKYGWGQTTPKEMATLLTLIRDGKMINPAASE +RIYRNLIRIFW-DTEALSQIPPTIQVASKSGAVD-AARSEVLLVNAPHGD-YVFCITTKN +QKDTSNEGWTMIRKLSNLLWNHy +>[subseq from] serine hydrolase n=1 Tax=Mycobacterium haemophilum TaxID=29311 RepID=UPI000655C155 +--EVSRQIQAVFTDAGCRGWLQARPVSTVEPAiNFRADEPVPTASIYKVLLLAAVARSFD +RGELDPSARVTIRPTDCTPGPTGFSTFIDPVVSWRDLARSMIVLSDNAAADILLAAV-GL +PRMDEIIDELGLASTRVIGGAAALYEIYDPDQTNATSAADSNTILAAIWTDTIASPHACS +YMRGVLAQQVW-PHRIKSGFPREISVAGKTGTIGK-IRSEVAVISLPNETPIAVSVFTHA +ARHSLPAVDRAIGTAARIAVT-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. WAC 06738 TaxID=2203210 RepID=UPI0013E0C96D +------------AEAGVTGQLHARDIDTGAEL-AVAADTPVSTASVHKVCLLATLYREAE +HGRVDLTAAVEVPAGGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI +EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLTAVWRDEVCTGAYAA +DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAGRLAVD-- +>[subseq from] Beta-lactamase class A n=2 Tax=Williamsia muralis TaxID=85044 RepID=A0A495K719_9NOCA +------QMTEVFADAGCAGWVHARTIGRGREF-GWAADDPVVMASVYKLPLLLAMCDLAE +IGQIDLTATVIVDPADWAVPTGIATLHDPVTLSWRDLAVQMMVISDNAAADVILDRV-GL +PRVQDKLDALGLTETRVVGGMAELQQAYDPALASATTPRDATRLLQLIWTDQAVSAQMSE +FVRSTMRKQAW-QQRLSSGFPLGVTIAGKTGTLG-AIRNEIAVVEYPGEHPIAVAVFTLA +ARLSLPTVEAAVGRAARIAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora taraxaci TaxID=1316803 RepID=A0A561W957_9ACTN +---------------------------AFREV-GVRADEQVVIASVFKILLVLEFARQVE +AGQLDPTERVLVTAADRLGGWGLAGCVDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLTRTRIRGGPRELVEVFDPAHTTSSTAREITRLLSMIWRDEAGPAGACA +MVRTWMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA +DQSRRIDVDLAMGEAARTAV--- +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. An122 TaxID=1965551 RepID=A0A1Y4T4V0_9FIRM +--TLEKRIAAELYSYHGQMSVFVDDL-QGHTV-EMGADEPFETASTIKAYILAALYLQAS +RGKASLEDTVTYRPEHFVDGSGMLRAGVGAALKVKDAATMMIICSDNIATNMIIDYL-GL +EEINRCIQELGFEHTVLHNPLH-FD---RYDKLGTTTPRDYAGLFARVARGTLVSREASA +DMLAIFRAQHY-NTMLTGNFPPYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKN +FDD-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. QMT-28 TaxID=2662397 RepID=A0A5Q0L9Z3_9ACTN +------------------PGTAGLTEPRAREV-AVGADEPVVLASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNSAADLLLDRV-GL +DTVRLLTQELGLTRTRVVGGPRDALEVLDPLRTNAGTPRETTELLRLIWRDEAASPEACA +QVRDLMSRQVF-RHRLASGFPGDTVIAAKTGTLP-GLHMEAGVVGYPDGRCYAVSVFART +REVTGPEVDAAIGAAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNT371 TaxID=1136433 RepID=UPI0004AE39FE +hrTARSRIRRAFAEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE +HGRVDLTAAVDIPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI +EAVNRTMTALGLTRTTAVQKVRDLYAVLDPARTNRSTPRELTALLAAVWRDEVCTGVYAA +DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Selenomonas sp. AE3005 TaxID=1485543 RepID=UPI00068C574D +---LAQNTQSILGTESKGFSVYFLRPEREVEP-YIHNQRAMMPASMIKLFVMAKVMQDVH +DKRLFLDEQLTIKRKDVVGGAGVITWYNAGERTILQLVKLMITDSDNTATNMLIDRV-GL +TQLNAYLSQQGFKDTVIANKMMTGNRG----RKNFSSVRDIGHLLTRMYYRELVAEEEDS +IMLDILLEQND-KECFPKALP-AYKIAHKTGEID-GVFADGGIFFGPQGTFILVAI---- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. B7740 TaxID=1564114 RepID=UPI0009E197A8 +--TTDEQLRAVFADAGCRGWVRAERIDGTGTVvDYEGDDPVVAASVWKIVLLVAVARAFD +EESLTATDSVRLVPAQCSPPTGIASFADPVTMSWRDIARSMITVSDNAAADALLGAV-GL +DAVARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTILRSVWLGTAASPAQCR +YMKDVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA +ARMDLPLVDQAIGHAARIAV--- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536LW71_9CHLR +---LEGELLRIGSTYSGKWTYALTDMSSGQKI-GHRQDDVMPTASLIKVPVLTALYRAVH +EGRLRLTDRIRYGDEHRCLGSGVLSRLTPGVMTVRDAAVLMIIISDNSATNFVIDLV-GL +DQVNETMRCFGLGRTTIFQRLGDTKAGLDARKMSVSTAGEMTRLLELIARHEAVPPEASE +DMLRIMRRQDY-RHELSRLLPTENWVAEKGGSFLNGIRTSGAIFNGSRG-KFVMSVFCEG +GTGP------------------- +>[subseq from] Serine hydrolase n=1 Tax=Subdoligranulum sp. APC924/74 TaxID=2086273 RepID=A0A367GEB4_9FIRM +---LERRIDAELCGLDAKMCVYADDL-HGHVV-ERGADDEFESASTIKIYILGCLYAQAE +AGKASLDAELTYEARHFVDGSGLIRSLGEGALRARDVATLMIVVSDNIATNMLIDYL-GS +DTINAFIRSIGCTHTKLHRSLRSDNW---SEKLGTITPRDMGRFFALLAKGELVSPQASD +AMRNVFRQQHY-NTMLAGSIPPYIYVASKSGSMD-ACRNDGGLIHTPYGD-YVLVMMCTD +FANKLEVND-------------- +>[subseq from] serine hydrolase n=1 Tax=Bacillus massiliogorillae TaxID=1243664 RepID=UPI0003A49224 +--NIHKILQQQLQQYQGNFAYVISH--DSSKI-EHNSSVITSSASTIKIPLLIEALRQCE +EGRLHLGMMISIPKRDIVGGAGVLQSLVVTSLSLRDLLALMIIVSDNTATNLVIDVL-GL +EQIKNGYKRIGLHSTSVQRKMMDFES-LKNGKDNLISAEDLHKCLLIINEPSILRKDSQK +VMHEMLEKQQF-REKLPYYMDESMWIGNKTGELP-GVEHDCAIIKYGPHT-VYAVILCSD +LE-QQQDGKQLIRVVGQTINE-- +>[subseq from] serine hydrolase n=1 Tax=Arsenicicoccus sp. MKL-02 TaxID=2663847 RepID=UPI0012B5402B +--VLQRDLKDIVRHAPGRLSIQVVG-PEGVLA-GWDSNRGVPAASLVKVLVLVATLREVE +AGRLSLDQTLRIP-DDRVGGAGALSLLPSVVLSVVELLRLMVTLSDNDAANLLLRLL-GH +DRVTRCGLELGLRHTHVRRDLMDSRSA-SQGRDNTTTAADQAGLLAVLRAGQALGAQQTA +LALALLSEQQH-AYGVTALLPDDVVRGSKPGDLP-GIRHDVALIETG-GAWAAVAVTATG +MYDDR------------------ +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000B419B04 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAELTKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] serine hydrolase n=1 Tax=Desnuesiella massiliensis TaxID=1650662 RepID=UPI0006E37309 +-----KEIKRYLESRIGQYSFYFEDLDGGYIY-GFNENVKMTSAGCMKLPVAMALFKEIE +NNKISLDTKLSICGDDKVFGTGIIHEFCERDYTVLELVIAMLIQSDNTAANKIIDVL-GI +ERINEIIKDMGLSNTELNRKTMDEK-NVRDVVENLTSSFDLCKCWKHLYKHTYLSEEHSN +KLIDILRRQQL-KNKVAFYIPENFTIASKSGDLE-GIENDTSIIQIPKGN-FAFTVMSKG +VP-NNVYGNVTVAKCGKMVWD-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium baratii TaxID=1561 RepID=UPI00097FAC8A +-----KEIKKYLESRIGTYGFFFEDLNSGFVY-GYNENVQMVAAGCMKLPVAMALIKDVE +LGKVTFMDKIRIDGADKVYGTGIIHEFDARDYTIFELLVAMLIQSDNTAANKIIDIV-GM +ERINDYLKEMGLKNTVLNRKTADERKE-KPKVENLTTAKDLSMIWKILYDATFLSKENST +MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKP-GVENDTALIQLSKG-SFTFTVLSMS +IPNS-VYGTVTLAKSGKMMWD-- +>[subseq from] Serine hydrolase n=1 Tax=Mycolicibacterium sp. P1-18 TaxID=2024615 RepID=A0A5A7XZ13_9MYCO +--DVTARISEVFADAGATLHAVAADGSSADDV-DVDGDRPVAIASVYKLPLLVAMMRMVD +GGRLDPTEAVTLRPDDRTVPTGISTLSDAVTMSWRDLAAMMMAVSDNAAADAILRRV-GI +DDVAETLRALGLPRSRIVGGTADAYRAYDPVHSSSATARDMTTLLTSIWTDRAATPPSCA +VIRTLMSRQVR-NARIASGFATGVRIAGKTGTLG-ALRHEVGVVQFDDERPYAVAVFTQS +ARAAQPRVDAAVGYAARLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=UPI000995E951 +---IEKRIAEVFAEADAEARLHAVDIDPGREL-GLGVDDQVVIASVFKILLVLEFARQAD +AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL +DTVRLLAAELGLDRTRIVGGPRELLEVLDPGHTTSSTPRDITTLLGLIWRDRAGSPAACA +LVRELMSRQVF-RQRMASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART +ASAARTAVDAAIGRAARLAV--- +>[subseq from] Beta-lactamase n=1 Tax=Fibrisoma limi BUZ 3 TaxID=1185876 RepID=I2GP14_9BACT +--KLERKLASLLDGFQGDVGLYVRHLRTGRTV-AINADTLFPTASTIKIPIQCGLFAKLA +AGELTYQQELIYRDSLHYDDGIVGSLKDGAKIPLSQVVMLMETISDNTGSLWCQALAGGG +QTINTWLDANGFRQTRVNSRTPGREAYRKLYGWGQTTPRELAELLVYIREGRAISPDASE +RMYRNLSRQYW-DGDALSQIPPDVKVATKNGAVNQ-SRSEVVLVHAPHGE-YVFCLMTKN +QKDESNEGATLLRHVSALIWQHf +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A291TA60_9FIRM +--TLEKRIAAELYSYQGRMSVFVDDL-RGNTV-EIGADEEFETASTIKAFILAVLYLQAS +RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA +AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE +FHD-------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Oceanobacillus sp. E9 TaxID=1742575 RepID=A0A1E5K5C3_9BACI +-------------------------T-KDGDI-GIEEEKVYSSASTIKVPILMEALLQGE +QGIINLDEKITVSDSDITSGGGIIRHMSANQLSLRDLLYLMITQSDNTATNMIIERV-GM +DSVNQTIAEMGAEDTILQRYMMESVR--PN--DNLTSAKDMATIMQSAFESDILSSENKE +EFLRIMGEGIL--SHYRSDRHKDISNYSKGGSLGTNVRHNIGMFTYQDE-VVYVSVMSED +AE--LKSSRIVMAEIGERVMDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Hungateiclostridium clariflavum (strain DSM 19732 / NBRC 101661 / EBR45) TaxID=720554 RepID=G8LU97_HUNCD +-eNLKNELEEYVSRFTGQYGIYFVDLVSGYEF-GINDTDEYTAASTIKVPLNYYIFKMIE +AGEVDPEDTIAYKEDDFEGGTGILQSKKLKGFTIRYLLKVSIIYSDNIATNMLLRHF-GR +KNFKNYLRMLGGTVV--------------DDNKNVSCPKDMAIYLKNIYEFCNENKELGK +ELKYNLCNTIH-NDRLPRLLPKDVKVAHKIGDQIQ-AVHDVGIIYADN--PYILAVMSKG +VI-SDEEARSVIAQVSKKVYD-- +>[subseq from] serine hydrolase n=1 Tax=Hungateiclostridium clariflavum TaxID=288965 RepID=UPI000487EA7B +-eNLKNELEEYVSRFTGQYGIYFVDLVSGYEF-GINDTDEYTAASTIKVPLNYYIFKMIE +AGEVDPEDTIAYKEDDFEGGTGILQSKKLKGFTIRYLLKVSIIYSDNIATNMLLRHF-GR +KNFKNYLRMLGGTVV--------------DDNKNVSCPKDMAIYLKNIYEFCNENKELGK +ELKYNLCNTIH-NDRLPRLLPKDVKVAHKIGDQIQ-AVHDVGIIYADN--PYILAVMSKG +VI-SDEEARSVIAQVSKKVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Subtercola boreus TaxID=120213 RepID=A0A3E0VSH6_9MICO +------------------------------------------------------------ +--------------------------------------------------------MGGP +AALDAALRDQGDDVSEAVNSEPALNVIEPGSTDDTSTPAAFTANLSRLIAGSYLAMDDRM +LLLEWMTGNATGDTLIRAGAPSGWNVADKSGGAG-GIRNDIAVVTPPGGHPIVLTIFTNT +LDPDAAYDDALVADVARAVL--- +>[subseq from] serine hydrolase n=1 Tax=Paracnuella aquatica TaxID=2268757 RepID=UPI000DEFDB4B +hkKLQQAIEQMAVGFGGQVGIYVKDLRSGRMA-AYNADTIFPTASIVKIPIAVGIMQKLE +RGELTYHQPLVYKDSLLYPGVDILGSFKNGEIDLSKVLMLMLTTSDNTASLWLQSLAGGG +TTVNVLMDTLGFPQLGVNSRTPSREADREVYGWGQMTPRAIAGLMEEIYRRRVISPAASD +RLLRLLNRNYWDAEALSEIAP-YAAVFSKNGAVNE-SRSEVVLVRGKKSA-YLFCIATKN +NRTPDNEAWTLTRKLSAYLWQHf +>[subseq from] Serine hydrolase n=1 Tax=Deltaproteobacteria bacterium TaxID=2026735 RepID=A0A534PPZ1_9DELT +-----------AAHAAQTIAISFHDLQTGQRV-ELAAGERMHAASTMKLAVLLAAHR-L- +--ELDLDQPVRVENKSLADGSDFSYTQLGREVPLRVLLERMIIRSSNLATNLVLQRL-DA +ARITQVCRELGARDIEVLRGVEDGKA-FAKGLNNTTTAHDLAVLLEAS--------AAQP +EIVELLARQEF-NEGIPAALPKGTRVAHKTGDIDR-IYHDAALVYPPGRKPYVLVVMTRG +FA-TLEQGAAAVREVSRAVWQ-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=UPI000BFF755E +haAARRRITAAFADAGVTGQLHAVDIDTGTAL-GIGSDTLVPTASVHKLCLVATLYRQAS +LGLVDPTRPVEIPAIPAEGGATGLSMRDAARLSLRDLASLAVAVSDNTAADLLWDAL-GL +DTVNATMTGLGLTRTHAVQTMRELFAALDPTRTNRSTPREITALLAAVWRDEVCPGEYGE +ELRALLGLQAW-NHRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA +ASTDLPAADAVIGGAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=UPI0012AF4D24 +--TLEKRIAAELYSYQGRMSVFVDDL-RGSTV-QIGADEEFETASTIKAFILAVLYLQAS +RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA +AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE +FHD-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium septicum TaxID=1504 RepID=A0A386PH62_CLOSE +-----KEIKKYLESRIGTYGFFFEDLKSGFIY-GYNENVQMIAAGCMKLPIAVSLISAVE +QGKVDFMDKIKIDGKDKVYGTGIIHEFNEREYTVFELLVAMLIQSDNTAANKIIDIV-GM +EQINKDIQKMGLKNTFLNRKTTDE-RKPKNEVENITTASDLSKIWKHLYEGTFLNADNSQ +MLVDILRRQQI-KNKSALYIPDDYEISSKTGDKS-GVENDTALIQLSKGN-FVFTILSMS +IPN-SVYGTVTLAKCGKMMWD-- +>[subseq from] Beta-lactamase 3 n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A564T657_9FIRM +--TLEKRIAAELYSYQGKMSVFVDDL-HGHTV-EIGADEEFETASTIKAYILAALYLQAS +RGKASLEEKITYKPEHFVDGSGMLRAGVGASLKVKDAATMMIICSDNIATNMVIDYL-GL +DTINACIREMGFAHTVLHNPL---HFDIYSD-LGTTTPRDYASLFAQVAKGTLVSAEASA +EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] Beta-lactamase class A n=2 Tax=Amycolatopsis mediterranei TaxID=33910 RepID=G0G3W8_AMYMS +--------------VGVRGFLHAHRLGSSREC-GLDADSPVVMASVVKVPLAFEFARQVA +AGQLDPTDRVRASAADRLGGTGSAAFADDAEYSLRDAALLALSVSDNTAADLLFDRV-GV +DNVRSLLAELGLTRTTVIGAPRDVLRALDPLRTSATTPREMTTLLAAIWADDVGAP---- +-VREWMSVQ-VGWHRLTAGFPPEVAVAGKTGTMP-GIRNEIGVATYPDGTAYAVAVFTTG +GAETRPDIDRAIGAAARAAVDQ- +>[subseq from] Serine hydrolase n=1 Tax=Planomicrobium sp. CPCC 101079 TaxID=2599618 RepID=A0A5C5SV28_9BACL +-----KKIEERLLNVDSNYSMFIE--TEGQSI-SINPDKKMRAASVIKLPILIEGYRQID +NGEINAKVGIVWSEKDLVGGSGVLADLTSVHLSLPDILMLMTIVSDNTASNLAIKHL-SI +EKINRLSEVLGCTNTILGRQFMDFEAA-EKGLDNYTSARDMVLFLKEAETGKILSEESKQ +QVKHALSQQQF-VANLHGRFDSEVIIASKSGSLE-GVVNDVGIFEYRGMK-VYAAVLLDN +LP-DNHTGQEIIADIGWYVYEY- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=A0A1S6RQ16_STRHY +---IEKRIAEVFAEADAEARLHAVDIDPGREL-GLGVDDQVVIASVFKILLVLEFARQAD +AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL +DTVRLLAAELGLDRTRIVGGPRELLEVLDPGHTTSSTPRDITTLLGLIWRDRAGSPAACA +LVRELMSRQVF-RQRMASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART +ASAARTAVDAAIGRAARLAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonas sp. SG8_23 TaxID=1703356 RepID=A0A0S7YUG0_9BACT +--DLEARVTARLDALDAVSSLYARHLPSGREI-AVRADRPMNTLSVIKIPVMVQAFLDDR +SGRLDLDARRTVRPEDLRRGSGLLQTFAPGLPTLRGLVTQMIITSDNTATDMVIDAV-EL +DRVNALLEREGYRETRLRMTTGDLFRRFEGDSTGRTTAREMGRLLQQILEADLADREASD +EMIGMLRSQFY-TSRLPQRVRQDVGVAHKTGDWPPIAGNDVGILFYEGG-PAIVSVFTNQ +NRGDFFELEATLGLIAEDVVTAw +>[subseq from] Serine hydrolase n=1 Tax=Clostridium indicum TaxID=759821 RepID=A0A3E2NA34_9CLOT +--TLEKRIQAEIMSYDGKMGIYLNDF-HGNEF-ALGQEEKYETASTIKTFILASLFDEVE +KGNKSLEDFVEYKKEHVVDGSGVLVSLEPGALRIKDAAVFMIIVSDNIATNMIIDYL-GL +DTINRCIEKLGCKDTVLYNPIHFDQY----RRLGTSTPKDYGSVFTRLVKGELVSPQADA +AMIEILKKQHY-NSMITKDFPPVITVASKSGSMD-ACRNDGGIVFTPYG-PYVIVMFHKE +FSDAAHPATVFGARVSRLVLDQf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces niveus TaxID=193462 RepID=A0A1U9R4A5_STRNV +--------------LGARLWLHARCVDCGRAA-GHAEDEPVVLASVVKVLLVLEFFRQAA +AGQLDPAERAVVRAADRLGGTGTAGFHDDVELSLRDLALMTMSVSDNTAADILFRRV-GR +DTVQALARQLGLERAQVTGAPREVLEALDPARTTSATPREMTRLLSLVWNDRAGAAAACA +GVRELMSLQVN-GARLGAAFDRFTTVAAKSGTLP-GVRNEIGVVTYPDGARYAIAVFTRT +TSTRRPDLDTAIGGAGREVVE-- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006681122 +-qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNAATNALIDLL-GF +DAINQWSQRAGLAASRLQRLMMDTAA-REAGRDNFTSADDATAALCWMLRDGMLPSPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Serine hydrolase n=1 Tax=Nocardia ninae NBRC 108245 TaxID=1210091 RepID=A0A511MGK3_9NOCA +--------QEIFRDVGVQGWVHARCFDCGAEV-GSGADEPVVLASVVKVPLVLEFARQVA +AGQLDPTDRVRAGALDRLGGVGTAGCHDDVDLSLRDAAFFAITLSDNTAADLLFERV-GI +DNVRSLVRELGLAGTRIVGAPRHIVQALDPQRTTASTPREMTRLLTLIGEDRAGSAEACR +WVRDLMRQQLN-WHRLAAAFPPEVGVWAKTGTLP-GVRNEIGVLEYPDGSRYAVAVFTRA +GTQRLPEVDRAIGAAAAHAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2500 TaxID=2512214 RepID=A0A4R2CJY9_9ACTN +----NARIRAVFDDAGARGWLHAISLDRPEDSvELDADVVVPIASVYKLPLLAGFCRLVD +AGELDPCEQLTLSPESRIPGPTGLSILADPVMSLRDLAVTMMSVSDNASADALLNKV-GP +GRLAELLQSVGLEHTRVRRGAAGLVEVYDAANLSAGSARDMTLLLREVWGGRLLSEGQTA +FVRRAMEQQVF-TQRIAAGFPDGVRIAGKTGTFG-ALRHEVAVVTLPGGDAYAVAVFTHA +ARGDLPRVDAAIGEAARLAVDH- +>[subseq from] Beta-lactamase enzyme family protein n=1 Tax=Selenomonas sp. CM52 TaxID=936381 RepID=J6HU85_9FIRM +-eALRADFSAILAQKSPDCSVFLLRPREEKEP-LLYQSHAMQPASMIKLFILAYAMQQAK +DGTISLAEPLSITEANIVGGAGQLNWYDRGKLTIEQLLERMITDSDNTATNILIDRL-GI +ENIDGYIRQKGYADTCLQHKMMLSNQG----RPNLSSVKDIGTLLSLIYRGECVDYEHDK +KMLQILSRQKD-KDCLPSALP-AFLVANKTGEIT-GVYADGGIAWSDAGD-LILVVMDEN +CR-DRQETIALFQRIAQRA---- +>[subseq from] serine hydrolase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=UPI0007BEF828 +-qHVDAALTPLLAATPARVSLSLRDLDGGVVL-ARHADRMQPSASIIKVPILLALLEAVA +NGRYALEQPLALPAAERAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIELL-GF +DEINQWNQRAGLPASRLQRRMMDAAA-REAGRDNFTSAEDATASLCWMLRDGALPAALRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sagamiensis TaxID=47875 RepID=A0A562WHB8_9ACTN +--------------VGVDARLHAVDVDTGHEI-GVGADEQVVIASVFKILLVLEFARQAA +DGQLDPTERVVVRAEDRLGGWGTAGCADDVELSLRDLAYFAMSVSDNTAADLLMRRV-GP +DLLPLLATELGLTRTRVIGGPRQLLEVFDPDRTTSSTAREITRLLTLIWRDEAGPPAACA +MVRDLMSRQLF-WTRLPSGFPPDVPVAAKTGTLP-GLHMEAGVVRYPDGGRYAIAVFAQT +RRTRRIDVDLAMGEAARMAVE-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia suismassiliense TaxID=2077092 RepID=UPI000D1DBB3D +--------QEIFRDVGVQGWVHARCFDCGAEV-GSGADEPVVLASVVKVPLVLEFARQVA +AGQLDPTDRVRAGAVDRLGGVGTAGCHDDVDLSLRDAAFFAITLSDNTAADLLFERV-GI +DNVRSLVRELGLAGTRIVGAPRHIVQALDPQRTTASTPREMTQLLTLIGEDRAGPAEACR +WVRDLMRQQLN-WHRLAAAFPPEVQVWGKTGTLP-GVRNEIGVLEYPDGSRYAVAVFTRA +GTQRLPEVDRAIGAAAAHA---- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. SN20 TaxID=1776383 RepID=UPI000C7822D2 +--ELDAWLREQIDAFPGKVSLLMTDLINGKHYhSFDPDTQVVSASTIKVPILLYALEQVR +QKRLSLEQAVPVPAESILPDTEVFELCLP-EYSLWELLYWMIVESDNTATNLVLDLL-NW +DEMNAYFKDLGLKHTVCQRKMLDWDA-VAAGKNNYTSAADQERIYWALYRGTILTHDLQE +KALDMLRRQRC-NDSFLRYIPQPVVVAHKTGGLDH-VNHDAGIFELFSH-PFYLGIFTWD +GPDGQPDQKRFIGKLAKQIYEIy +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. An192 TaxID=1965581 RepID=A0A1Y4JAY3_9FIRM +--TLEKRIAAELYSYHGQMSVFVDDL-QGHTV-EMGADESFETASTIKAYILAALYLQAS +RGKASLEDTVTYRPEHFVDGSGMLRAGVGAALKVKDAATMMIICSDNIATNMIIDYL-GL +EEINRCIQELGFEHTVLHNPLH-FD---RYDKLGTTTPRDYAGLFARVARGTLVSREASA +DMLAIFRAQHY-NTMLTGNFPPYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKN +FDD-------------------- +>[subseq from] serine hydrolase n=1 Tax=Oceanobacillus kimchii TaxID=746691 RepID=UPI000A06F2ED +-------------------------T-KDGDI-GIEEEKVYSSASTIKVPILMEALLQGE +QGIINLDEKITVSDSDITSGGGIIRHMSANQLSLRDLLYLMITQSDNTATNMIIERV-GM +DSVNQTIAEMGAEDTILQRYMMESVR--PN--DNLTSAKDMATIMQSAFESDILSSENKE +EFLRIMGEGIL--SHYRSDRHKDISNYSKGGSLGTNVRHNIGMFTYQDE-VVYVSVMSED +AE--LKSSRIVMAEIGERVMDY- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. L-9-10 TaxID=1478131 RepID=UPI00101DBE4D +----------------------------RAEV-AIGADEPVVLASVFKVLLVLEFARQVA +AGQLDPRERVWVTADDRLGGWGTAGCLDDIGVSLRDLAHFAMSVSDNSAADLLLARV-GT +DTVRLLAEELGLHRTRILGGPRQLLEVLDPERTSASTPREITRLLELIWRDEAGPPEACA +QVRELMGRQVF-RHRLVSGFPDEVRVAAKTGTLP-GLHAEAGVVHYPDGGRYAVAVFART +GDTNRTAVDSAIGAAARIAVE-- +>[subseq from] hypothetical protein n=1 Tax=Streptococcus suis TaxID=1307 RepID=UPI00041ED443 +---------NIFGAIGGDKSFYVKSTS-GTEF-IHINDRVQRSASTIKLFILAAAYNKAH +RGELNLGAPYTVQASDIVKASTSLANAAGRTYTIGQIARFMVETSDNTATNIIIRKIGGV +SAVNAEIRKLGYTKTTLERFMHDPV-AIAAGLENYISAQEAADLITNILNKTLISAGADG +QMINDLSNNFY-ADWLTASIKQYALVFDKPGSHGYGVENDIAIITRNGQ-SVAVALLTQH +TGSNGR----------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Bauldia litoralis TaxID=665467 RepID=A0A1G6BWH2_9RHIZ +--VLEHRLTHLADSLRADWGIFVHFVNGGGEI-AINADRQQDTMSLIKVALLVTLMRKVE +TGEVDLATRVTLGDDDKRLGTGVLFLFDAGAFTLKDAAWLMIVISDNSATDIVLDAVGGP +EAVNQTMAALGLDQITMTGNALAWFRFGEDRPFALATARSLGLLMLQIHDHRCASPESCE +TMLAMLRGQQL-HSMLPKYMW-GVTAAHKTGNFPPFISSDLGIFTPAAGSPVIISIMTQQ +HRGQRALVEDTVARMGELIIH-- +>[subseq from] serine hydrolase n=1 Tax=unclassified Amycolatopsis TaxID=2618356 RepID=UPI00106E7521 +----RERIEAVFADAGAEGFLHAREIGPGPEV-SAGGDDPVVLASVFKIPVALAYAREVA +AGRLDDTERTKVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVLYHRL-GQ +ETVDRVLNDLGLERTRLIGCCEDLFAVRDPERTTSSTPREITELLDAIWTERAGEPEACE +RVRTIMAQQIW-PHRLSSGFPSGVAIAAKTGTLP-GIRNEAGVVTLGDGRRFAVAVFTRA +HSDRLPAVDASIGAAARLAVDH- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium saccharolyticum (strain ATCC 35040 / DSM 2544 / NRCC 2533 / WM1) TaxID=610130 RepID=D9R4T6_CLOSW +--TLEKRIEAEIMSYDGTMGIYLDDF-HGNVI-SVHADETFETASAIKTYILACLFDEVE +KGNKSLEDMIQYREEHVVDGSGVLGALEPGALRVKDAATFMIIVSDNIATNMIIDYL-GM +DTINRCIKALGFKDTVLYNPIHDIY-----RRLGTSTPRDYAGFFTRLAKGELISPKADG +KMLEIFKKQHY-NSMITKDFPPFITVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE +FSDADHPATVFGARVSRMILDQf +>[subseq from] serine hydrolase n=1 Tax=Spirosoma sp. HMF4905 TaxID=2682092 RepID=UPI0012F759E5 +-nALERKLQAALANFRGDAGVYVHNLRSGKIV-AINADTLFPTASMIKIPIQCGLFDKIH +TGELKYDQELTYKDSLHYDDGIVGSLKEGAKITLSKVVMLMETVSDNTGSLWCQALAGGG +TTINNWLETNGFHQTRVNSRTPGREANRNRYGWGQTTPREMAELVTYIRQGKAISSDASE +EMYRNLGRQYWD-NDGLSQVPPDVKTACKNGAVNQ-SRSEVVFVHAPHGE-YVYCIITKN +QKDETNEGSVLLRTVATTLWHHf +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter malorum TaxID=178901 RepID=A0A087PWV5_9PROT +---LAQIMAKTVSKQPGHFAVYAARSGQAPDV-CLNCDDLINAASTMKLFVLDTAYEAFT +KGTLHPEDTIVVHNHSLVGKGRFAYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV +LPIRSVVKAQSLNGIVFGRMIEDFDAN-DQGIRNQVSARGLGDFLQKLDSGQIVGKAQSQ +SMIQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVD-GVRNDAAIVTLPDGKRYILVVLTSG +LP-DEQAGIRVMNTLSHQAYEYf +>[subseq from] Serine hydrolase n=2 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A2A7BG25_9FIRM +--TLEKRIAAELYSYQGRMSVFVDDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAS +RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA +AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE +FHD-------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora chaiyaphumensis TaxID=307119 RepID=A0A1C4ZC87_9ACTN +------RIGEIFERAGISGCVHVEDVDTGRAV-ALRADEQVVIASVFKILLALEFARQVV +AGQLDPVERVLVGAADRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DVLPMLAAELDLPRTRIVGGPRQLVEVFDPAHTTSSTAREMTRLLRLIWRDEAGPPAACA +MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVVEYPDGGRYAVAVFART +ERLSTRDVDLAMGEAARTAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2568 TaxID=2512219 RepID=A0A4R1VWF9_9ACTN +----NARIRAVFDDAGARGWLHAISLDRPEDSvELDADVVVPIASVYKLPLLAGFCRLVD +TGELDPCEQLTLSPESRIPGPTGLSILADPVMSLRDLAVTMMTVSDNASADALLNKV-GP +DRLAELLQSFGLEHTRVRRGAAGLVEVYDAANLSAGSARDMTLLLREVWGGGLLSEGQTA +FVRRSMEQQVF-TQRIAAGFPDGVRIAGKTGTFG-ALRHEVAVVTLPGGDAYAVAVFTHA +ARGDLPRVDAAIGEAARLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus paraplantarum TaxID=60520 RepID=UPI000E714147 +---VSELVEQTMQDVAGRTSIAVMPLTGSQTV--IVNNGAQRAGSLITLFILVTAYDQVH +QNNWQMQDRYTLRAEDKVGGTGTLHTLPAGSLTYAEIAKRMITDSDNTAANIMLDRVGGV +SAINSEVAQLDLKDTTMARRLMDTA-ALKAGRDNYTSVRDVATILQRLANYRLISKRVDQ +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVKNRQGT-FIMTVMAAD +GEREAQT---------------- +>[subseq from] serine hydrolase n=1 Tax=Clostridium baratii TaxID=1561 RepID=UPI0009A3EB22 +-----KEIKKYLESRIGTYGFFFEDLNSGFVY-GYNENVQMVAAGCMKLPVAMALIKDVE +LGKVTFMDKIRIDGADKVYGTGIIHEFDARDYTIFELLVAMLIQSDNTAANKIIDIV-GM +ERINDYLKEMGLKNTVLNRKTADERKE-KPKVENLTTAKDLSMAWKILYDATFLSKENST +MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKP-GVENDTALIQLSKG-SFTFTVLSMG +IPNS-VYGTVTLAKSGKMMW--- +>[subseq from] serine hydrolase n=1 Tax=Arsenicicoccus bolidensis TaxID=229480 RepID=UPI0002EAE636 +-qTLQRDLKDIVRHAPGRLSIQVVG-PAGVVA-GWDSDREVPAASLVKVLVLVATLREVE +AGRLSLDQTLEIPE-ARVGGAGALSLLPSVALSVVELLRLMVTLSDNDAANLLLRLL-GH +DRVTRCGVELGLRHTHVRRDLMDDGSA-REGRDNTTTATDQAGLLAVLRSGEALGEQQTR +LALALLSEQQH-AYGVTALLPDGVVRGSKPGDLP-GVRHDVALIEAG-GAWAAVAVTATG +MY--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Selenomonas sp. mPRGC5 TaxID=2593411 RepID=A0A5D6W252_9FIRM +--SLAQAVTALSNSDSTQYALFVAYPGENREE-YSYQSKQMRSASMIKVFILGTAMEKVR +DGQLSLYQNLVLHSYDKVGGAGVLAGYASGTLTLDTVMRLMITESDNTATNMMIDLL-GM +EEINAYIKRNDYADTILQRKMMDSQAV-AEGRENYTSVNDLGHFFLKLYHRNCVSPELDD +VMLGYLEGQTD-TECFPAALP-GVMICHKTGELY-GLYDDGGIVYQPGK-HFILVGMTEN +YS-SRGRAISILKQMAKAAAN-- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=Clostridium vincentii TaxID=52704 RepID=A0A2T0BBV0_9CLOT +-----KEIKKYLESRIGTYGFFFEDLASGFIY-GYNENVKLIAAGCMKLPIAVSLIKAVE +DEKVTFMDKIAISASDKVYGTGIIHEFNARDYTVFELLVAMLIQSDNTAANKIIDIV-GM +DNINKNIQDMGIKNTILNRKTSDE-RIKKSDIENITTAYDLSIIWRHLYKGTYLTQENST +MLIDILRRQQI-KNKLALYIPDDFEISSKTGDKK-GVENDTALIQLQKGT-FVFTVLSTG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Bauldia litoralis TaxID=665467 RepID=UPI000B881D48 +--VLEHRLTHLADSLRADWGIFVHFVNGGGEI-AINADRQQDTMSLIKVALLVTLMRKVE +TGEVDLATRVTLGDDDKRLGTGVLFLFDAGAFTLKDAAWLMIVISDNSATDIVLDAVGGP +EAVNQTMAALGLDQITMTGNALAWFRFGEDRPFALATARSLGLLMLQIHDHRCASPESCE +TMLAMLRGQQL-HSMLPKYMW-GVTAAHKTGNFPPFISSDLGIFTPAAGSPVIISIMTQQ +HRGQRALVEDTVARMGELIIH-- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. chh4-2 TaxID=2067550 RepID=A0A2K2TNI5_9CLOT +--TLEKRIAAEIASYDGRMAVYADDLR-GNVI-AIYPDEKFETASTVKTYILACLFDQVE +KGNADLEGMLALKPEHMVEGSGVLCSEPGLKLRVKDVATLMIIVSDNVATNMMIEYL-GK +DTVNKCIRKLGCRDTVLHNDIHF-DR---YRRLGTTTPRDYAGMFIRLAKKELISEAADE +AMMSIFRKQHY-NSMLTGAFPPYISVASKSGSMD-ACRNDGGIITTPYG-SYVLVMMHKE +FSDSGHPATVFGAKVSRMILDQy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CNQ-509 TaxID=444103 RepID=A0A0F7NJ33_9ACTN +-----------FAEAGVTGQLHARDIDTGAEL-AVAADTPVSTASVHKVCLLATLYREAE +HGRVDLTAAVDVPAGGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI +EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLTAVWRDEVCTGAYAA +DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA +AAVTLPAADAVIGTAGRLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces exfoliatus TaxID=1905 RepID=UPI000463C471 +---------------------------GVEEV-AVGADEPVVIASVFKVLVVLEFARQVA +DGQLDPRERVRVTAGDRLGGWGTAGCADDVELSLRDLAFFAISVSDNSAADLLLARV-GL +DTVRLLAEELGLARTRIVGGPRDVLEVLDTQRTNAATPREITRLLRLVWRDEAGPPEACA +QVRELMARQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGGRYAVSVFART +REASRTAVDSAIGAAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. TRM68085 TaxID=2600619 RepID=A0A5N5EL65_9ACTN +----ERTIRSLFDDAGVRGWLHVADLHRSDRV-VVDPDEQVPMGSVYKVALMAAFCRLAD +AGRVDPRHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA +EAVDGMCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPAETARLLRAIWTDEAASPESCS +FMRAAMLTQPW-THRLASGFPDDLTVHGKTGTFGS-MRHEAGVVDFGDGSVYTAVVFTQA +ARADLPRADAVIGAAARAAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. H1 TaxID=2592048 RepID=A0A553UQJ1_9DEIO +------------QGYGGEVGLVISTLEGEELV-SLNAERVFLSASTIKVPLLLLALERVQ +AGQLRLTERHTLKPADRVGGAGILHELGAGLLSLGDLLTLMIIVSDNTATNMVIDLL-GV +DAVNAWLFERGCRQTRLVGKLDQQNAAQRLGERNRTSAAEQAGLLLGLWQGQRLEPPVRQ +LALSILGRQQYRDILGRSLLRPRYQTYTKSGELL-GVHHDVGLLMLP--RPLCVALLSEG +GSDR------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Lentzea albidocapillata TaxID=40571 RepID=A0A1W2BWW0_9PSEU +--------------AGVEGFVHAREIGDGPEA-GHGADEQVVLASVFKIPVAVAYAAEVA +AGRLDETARTRVTPRYRIGGIGTAGCRDDVEMSWRDLALFMMTMSDNAATDVIFHRV-GQ +AAVDAVVA--GLPRTRILGCCEDLFAIVDPERTTSSTPREITTLLDAIWTDRAAAPEACE +RVRAIMAQQIW-PHRLSSGFPADVLVAAKTGTLPS-VRNEAGVVTYPDGRSYAVAVFTRS +QSLDNPAADAVIGRAGRLAVDQ- +>[subseq from] Uncharacterized protein n=2 Tax=Candidatus Levybacteria TaxID=1752719 RepID=A0A1F6K7F1_9BACT +-qKLKQEVQKLVSSQKGSYSVYFHDLKTDVSF-GINEKQIHTAASVNKLPIIAVLYVLAS +TNKISLDEKITIQEKDIQDGTGKLRYEKQGGYSLKSLAQLALQESDNTAAHVLATRM-GS +DVIQNTIKEWGLTQTHIQN--------------NKTSLYDMYLLFQRIYEGKVARPHLRQ +ELLGFLTDTDI-EDRLPDLLPSSVKVFHKTGDAT-GGIHDVGIVEKDGM-VYFVGVLASD +VSSYEEQTRKTISKISSKIY--- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. MJM2582 TaxID=1427749 RepID=UPI000506EDB1 +--DIRERIEAVFAAAGAEGSLHAREIGDGAEV-SVGADDQVVLASVFKIPIALAYAREVV +AGRLDETEYTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWNRI-GQ +ETICRVVAGLGLTRTRLIGSCEDSFRMCDPERETSSTPRETTELLDAIWTDRAGEPEACQ +RVRAIMARQIW-PHRLSAGFPSDVRIAAKTGTLP-GIRNEAGVVTLPEGRRFAVAVFTRA +HSDRLPEVDASIGAVARLALDH- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces cyaneofuscatus TaxID=66883 RepID=UPI0004C93309 +---VERTIRSLFDDAGVRGWLHVADLHRPARV-VVDPDEQVPMGSVYKIALMTAFCRLAD +AGLVDPRHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHVVLRTV-GA +EAVDGMCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPAETARLLRAIWTDEAASPESCS +FMRAAMLTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSVYTAVVFTQA +ARADLPRADAVIGAAARAAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Woesebacteria bacterium RIFCSPHIGHO2_01_FULL_38_26b TaxID=1802491 RepID=A0A1F7Y2R9_9BACT +----TFEFRKMTEGLSGIYGLYVIRTEEGSSY-GVNENEVFTAASLIKLPVMIAMYKEVE +DGKINLDTKYKLRALDKTPGAGSLSSKPAGFVTYRDLLRLMGKQSDNTAFTITRNIL-GD +EKIIEIINELGMSQTSLDDN--------------ETTPYDIGMLFESLWNGNIVSEKSRD +ELLENLTDTIY-EDWLAAGLPDGTRFAHKYGREIH-VVNDAGIIFSE--SPIIVVVMSKG +IV--EKEADKVFPELARIIY--- +>[subseq from] serine hydrolase n=1 Tax=Kribbella sp. VKM Ac-2572 TaxID=2512223 RepID=UPI0010517105 +-----------------------------ATV-GVDADGVVPMASVYKLPLLAAFCRLVD +LGEIDPLSRLTLDPAERTAGPTGLSVLADPVMSLRDLAVSMMTVSDNASADALLDLV-GL +RRLAELLQSFGLQRTWVRRGTAANLRVYEAANASASSPRDMTLLLQRLWAGELLSAGQTE +FVKATMHRQVF-QHRMAAGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGAAFAIAVFTLA +ARGDQPRVDTAIGEAARAAVD-- +>[subseq from] Serine hydrolase n=2 Tax=Aphanocapsa feldmannii TaxID=192050 RepID=A0A524RL17_9CYAN +--ALSERFASLTATQDLRAGAYMVVLDDGSFA-QLNPTVPYAAASSIKLPILLLLLQDVG +DGRIDWNQRVIMRAELIGGGAGWMQGQPAGSFPLYEVARDMIRVSDNTATNMIVDLLGGK +EAVNRRWQDLGLTSTVLNNWLPDLGGT------NTSSAEDLCRSLALAELGEQLDLRNRD +RFREIMASSRT-DSLLPAGFLTGSQVLNKTGDIGT-AYVDAAQIELPDGRRALAAFMVVG +SEQTSPRSRQLIRDLATATAQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudonocardia ammonioxydans TaxID=260086 RepID=A0A1I5FJE6_9PSEU +------------------------------EV-AVGADVPVVMASVYKILVLVAYCRAVD +EGTIDPREPVVVPPARTPGGTGLSALADPVTMSWRDLVTSMVTVSDNAAADVVHTRV-GR +ERVAALPAELGLPGTRVAGGTEDVFAALNPAFGSSTTAADTTRLLALLWRGELTSAAGTA +FARRVLAAQIW-PHRLRAGFPATAAVAAKTGTVG-AVRNDVGVVSYPGEHPVAVAVFTHA +ARASVPRADAAIGAAARAAVQ-- +>[subseq from] D-alanyl-D-alanine carboxypeptidase family protein n=2 Tax=Clostridium baratii TaxID=1561 RepID=A0A0A7FWA3_9CLOT +-----KEIKKYLESRIGTYGFFFEDLNSGFVY-GYNENVQMVAAGCMKLPVAMALIKDVE +LGKVTFMDKIRIDGADKVYGTGIIHEFDARDYTIFELLVAMLIQSDNTAANKIIDIV-GM +ERINDYLKEMGLKNTVLNRKTADERKE-KPKVENLTTAKDLSMAWKILYDATFLSKENST +MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKP-GVENDTALIQLSKG-SFTFTVLSMS +IPNS-VYGTVTLAKSGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Acetobacter indonesiensis TaxID=104101 RepID=UPI000A3AA340 +--TLAHQIETTVQGQKGLFAVYAARVGARPEV-CLNCDHLINAASTIKLFVLDTAYKSFA +SGTLHPTDLIRVHNHSLVGKGTFAYAQQGKEVPVSELLRVMIQYSSNLATNLMIEKL-GV +FPIRDVVKEQALDGIVFGRMIEDFDAD-AQNIRNRVSARGLGEFLQKLDQGQIVGKEASQ +SMIAIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVKNDAAIITLPDGSHYILVVLTSG +LP-DEAAGVKILNVISQEVYDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1G7TFQ6_SELRU +--DLNRNIARILGGDSGRYAIYFWRPAEEEEP-FLYQNRPMSPASMIKVFIMAAVMQEVH +DGRLSLEEKLTIQEADVVGGAGVITWNIGESRSIRELVSGMITNSDNTATNMLIDRL-GM +DKINRYIQGHGYGDTQLVHKMMIGN----GGRKNFSSVKDLGKLFSRLYYHQLVGDTEDR +FMELVLSGQKD-RECFNAALP-DFTIAHKTGEVT-GLYDDGGIFYGRQGD-FVLVIMNEG +FT--------------------- +>[subseq from] serine hydrolase n=1 Tax=Clostridium TaxID=1485 RepID=UPI000665F2FF +-----KEIKRYLESRIGTYGFFFEDLSSGFIY-GYNENVQMVAAGCMKLPIAVSLIKAVE +DKKVDFMDKIKIEKEDKVYGTGIIHEFNEREYTIFELLVAMLIQSDNTAANKIIDII-GM +DNINSNIKEMGLKNTILNRKTSDERQS-KDGVENITSAYDLSKIWKHLHNATYLNRDNST +MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKK-GVENDTALIQLPKGN-FVFTVLSTS +VPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces niveus TaxID=193462 RepID=UPI0009908979 +--------------LGARLWLHARCVDCGRAA-GHAEDEPVVLASVVKVLLVLEFFRQAA +AGQLDPAERAVVRAADRLGGTGTAGFHDDVELSLRDLALMTMSVSDNTAADILFRRV-GR +DTVQALARQLGLERAQVTGAPREVLEALDPARTTSATPREMTRLLSLVWNDRAGAAAACA +GVRELMSLQVN-GARLGAAFDRFTTVAAKSGTLP-GVRNEIGVVTYPDGARYAIAVFTRT +TSTRRPDLDTAIGGAGREVVE-- +>[subseq from] Uncharacterized protein n=2 Tax=Fusobacterium varium TaxID=856 RepID=C6JLR6_FUSVA +-eKFEKKLLEILKKYNKKYGIIIKSLESEFFL-KVGNMEAYPAASLIKLPILYELFNNSK +---YNLDEKIEITLKDKVGGFGIIQYHNNVKLSLRDLAILMIILSDNTATNILIDIC-GM +DNINFTLKKLGLKDTKLRRKMMDLKSK-NMGLDNYTSPYDMIKLLEVLNK--------NE +EIISIMKKQLC-NNKISHFIEKKIDFAHKTGDLPQ-IEHDVGIFDIEDKK-IIVVVMTKN +FENR--DEIELNNKVGEFI---- +>[subseq from] serine hydrolase n=1 Tax=Nocardia sp. CY41 TaxID=2608686 RepID=UPI00135B431F +--------QAIFRAAGVEGWIHARCVHCGAEA-GAGADEPVVLASVVKVPLVLEFARQVA +AGQLDPADRMRTRAADRLGGVGTAGCADDVELSLRDAAYFALTISDNTAADLLFDRV-GL +DNVRSLLRELDLPATRVVGPPRAIVQALDPRRTTASTPREMVRLLTLIARDQAGAPEACR +WVRDLMRQQVN-WYRLAAAFPPDVQVWAKTGTLP-GVRNEIGVVEYPDGKCYAVAVFTRA +ATQRLPEVDRAIGAAA------- +>[subseq from] Uncharacterized protein n=1 Tax=uncultured Paludibacter sp. TaxID=497635 RepID=A0A653AGG9_9BACT +-kKLTKLIENQVAGFNGTIGVYVKNLKTDKEA-FFNADTVFPTASTIKVPIMVAVFDKIE +KKELKYYQPLTYSKKELYKDDGLIASLRDSTVPLSIVQMLSICTSDNSASLWLQELAGTG +TVINELMENIGLKDTRVNSRTPGREKIREIYGWGQTTPREMTQLLEKIRNREIISPAACD +EMYRILGTIYY-RDRALSQIPPTINTASKQGMVS-AARSEAVLVNAPHGD-YVFAVYTKN +QKGKDNEGRKQIIQISALLWNYf +>[subseq from] serine hydrolase n=1 Tax=Nocardia amikacinitolerans TaxID=756689 RepID=UPI0008316350 +----EERIREIFAELPVRGQFHAVDLADGREI-GVDADDQVVIASIFKILLILEFSRQVD +AGQLDPTERVLVRAADRLGGWGTAGCADDVEMSLRDLAYFTMSVSDNTAADLLLRRI-GP +DTPALLTAELGLGATRVIGGPRQLLEVFRPEHTTSSTAREITRLLGMIWRDEAGSPAACA +ATRDLLRRQMF-WTRLAAAFPDEVLVASKTGTLP-GLHMEAGVLEYPDGGRYAVAVFARS +DETRRIDVDLAMARSARLAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Salinimicrobium sediminis TaxID=1343891 RepID=A0A285X5L6_9FLAO +-kELEKALKEITSDFNGDVGIYVYNLKTNKEA-AINADTIFPTASVIKVPILLGVFQKII +NGELKYNEPLVYDAKRAYGGSGLMQFYKDSTTDLRTSLALMMGYSDNTSSLWNQELAGGG +EGINTLLESLNFQDTRVNSRTKGREDIWKRYGWGQTTPREMTDILVKIRRGEMFNSAASE +EMYRLMTNSFY-TDYALSEIPPYVQSASKQGMVDD-SRSELVMVNAPSGD-YAFYFTTKN +IEDEENEAWELSREISAFLWNYf +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. L-9-10 TaxID=1478131 RepID=A0A4Q4DL75_9ACTN +----------------------------RAEV-AIGADEPVVLASVFKVLLVLEFARQVA +AGQLDPRERVWVTADDRLGGWGTAGCLDDIGVSLRDLAHFAMSVSDNSAADLLLARV-GT +DTVRLLAEELGLHRTRILGGPRQLLEVLDPERTSASTPREITRLLELIWRDEAGPPEACA +QVRELMGRQVF-RHRLVSGFPDEVRVAAKTGTLP-GLHAEAGVVHYPDGGRYAVAVFART +GDTNRTAVDSAIGAAARIAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Lactobacillus plantarum subsp. argentoratensis TaxID=271881 RepID=A0A512F013_LACPN +---VTDLIEQATNGLAGQTSVAVMPLAGSQSV--VVNNHAQRAGSLITLFIMVTAYDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANQRLISSKVDH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVRNRQGT-FIMTMMAAS +GER--TAQTSAMNDLGQVLYR-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. YIM 132580 TaxID=2691958 RepID=UPI00136A7094 +----EAAIRALFDDAGVRGWLHVAELERSARV-VIDPDEQVPMGSVYKVPLMTAFWRLAD +VGRVDPSHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA +DVVDRVCAELGLPHTRIHGGVVGTFDVYDPAYKASSTPAEIARLLRAIWTDEAASPGSCS +LMRAAMRTQPW-THRLASGFPDDVTVYGKTGTFGS-MRHEAGVVELADGGLYTAVVFTQA +ARADLPRADAVIGAVARAAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Gordonia rubripertincta NBRC 101908 TaxID=1077975 RepID=L7KEF0_GORRU +--RIDRNVAEILADAGCSGWLHATTIGSPQISySYDADAPVVLASVYKLAVLISLCRSAD +RGEIDLTSPVTVDPTRWAQPTGLAALRDPITLSRRDLATSMMTVSDNVAADVLLDEI-GL +DRVREDLIGLGATSTRIVGGVAELHEAYDAAYTSSSTPRDCSTLLSAVWTDRAASAEMCA +FIRDTMRRQVF-TSRLASGFPRRVTVAGKTGTLV-AIRNEVGVVEFPGELPVAVAVFTRS +ARPALPQVDRAIGELARTVVT-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI00080B4C3B +-----ASIADVCDDANATVAFHVRSLDGNLEI-GSGADARSVTASTYKVPVMLEVAAQAS +EGRIQLADRIKVPADRRTIPSGISAMTDEVEVSIRDLALLMMQVSDNTATDILQEMV-GT +ENIMSRLRALGLNSTSITTDCEGIISSLNARGGNTSTPREMTELLSLIWTDKAADAEACA +EVRRVMGLQFA-PHRLSSAYVDGPTISGKTGTFLAGVRNEVGVVDFGDEGLYVVAIFLRD +KNNYNSKVDAAIGKIAALAI--- +>[subseq from] Peptide methionine sulfoxide reductase MsrA n=1 Tax=candidate division BRC1 bacterium HGW-BRC1-1 TaxID=2013722 RepID=A0A2N2PMS4_9BACT +-----GKLEQIVAGHEGRMGLSVVNEDTGETF-EVNADAEFVTASTIKLGVLGTAFDLLT +SPSKSYYSTMVYDGSTSAAGAGFIQNYKGTRIELKELVHFMITASDNTGTNMLTKWVGGP +QAVNAWLASKGLARTRMNATIGGGQVADQALREGVTTPAEMRRLMQMYAEGKAVDTTASE +EILRVLGHQYF-DDDIASQVPPTMWVGSKSGAVN-ASRSDVAIMSTPGG-LIVMAVYTDN +NREDDNAGEVSIRRVAKEVFDHf +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A3E2U8F9_9FIRM +--TLEKRIAAELYSYQGKMSVFVDDL-HGHTV-EIGADEEFETASTIKAYILAALYLQAS +RGKASLEEKITYKPEHFVDGSGMLRAGVGASLKVKDAATMMIICSDNIATNMVIDYL-GL +DTINACIREMGFAHTVLHNPLH---FDIYN-NLGTTTPRDYASLFAQVAKGTLVSAKASA +EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Williamsia sp. 1138 TaxID=1903117 RepID=A0A261CZM9_9NOCA +----GQRLREIFADAGCAAWLHARTIGPQREF-GWYADDPVVMASVYKLPLLAALCVHAD +RGDINLRDTITVDPRECAEPTGIATLHDPITLSWRDLAVQMMVVSDNAAADVILAEV-GL +DGVREVLNGAGLHSTHVVGGMAQVQQAYDPAFASATTAREATCLLDLIWTDRVASVDSCE +FIRTTMRKQAW-KQRISSGFPLGATVAGKTGTLG-AIRNEVAVVEYPGEHPVAVAVFTHA +ARLSLPTVEAAIGQAARVAVN-- +>[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. 16K309 TaxID=2530384 RepID=A0A4R4VNT9_9PSEU +-------LA--ELELPGRVGIASWDLRENVPV-LRGAEVEVHSASTIKVLVMITALRAVA +DGRLDLDAQVELP-ADRTKGTGVLFEVPSVPASLRDLINLMIVISDNAATNAVIDQV-GF +AAIAECTADLGCTGTRIERHIMDTEA--PGVLR--TTALDQARVLTALAEGTALPPQLTA +HALTVLSRQQV-VDRIPLLLPENARCWNKTGEIK-GLRHDVALLSTDDTPQVVLAVLVDQ +LTD-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Runella sp. HYN0085 TaxID=2259595 RepID=A0A344TQB7_9BACT +-kKLTAQLQEAIKGFRGDVGVYVRNLKTNKIV-EINADTLFPTASMIKVPIQCGLFDKIA +KGELRYNAILTYKDSLHYEDDIVGSLKDGAKIPLSEVVMLMETVSDNTGSLWCQALAGGG +KSINEWLDKNGFTATRVNSRTPGREANRTRYGWGQTSPREMAELFAMIRQGRAISPDASD +RMYRNLTRQYWDGEGL-SQLPPDIKTACKNGAVNR-SRSEAVLVHAPHGE-YVYCVITKN +NLTSQNEGYVLLRKISKQLWNYy +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. 06-418-5 TaxID=2022507 RepID=UPI000B9AE07B +--TTDEQLRAVFADAGCRGWVRAERIDGTGTVvDYEGDDPVVAASVWKIVLLVAVARAFD +KGSLTATDSVRLVPAQCSPPTGIASFADPVTMSWRDIARSMITVSDNAAADALLGAV-GL +DAVARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSVWLGTAASPAQCR +YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA +ARMDLPLVDQSIGHAARIAV--- +>[subseq from] Serine hydrolase n=1 Tax=candidate division WWE3 bacterium TaxID=2053526 RepID=A0A3A4ZB65_9BACT +------ALKKVLEQQGTKYSLYIEDLATGKTY-AYNAQERTYAASMYKVPVAAAVLKSIQ +DRNLSFTTELIYAQSDYADGTGVINRQFGTKFSVEQLLTHLLDDSDNTAQNMLLRKV-SK +AQVGTLISQ------NIDNPSQSIFAA-----ENTATATEMATFLKNMYKKDVLTQENKN +FLFNEMKQTAF-DDRITQHLKPELSFAHKIGNWDTGSWHDCGIVFGSNDK-YVVCVMSRG +TT--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. NRRL B-16802 TaxID=1415541 RepID=A0A0N0TKG1_9ACTN +--------------------LTVGQLGGGREV-GVRADEQVVIASIFKILLVLEFARQVE +AGQLDPTERILVTADDRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLTRTRVLGGPRELVEVFDPLQTTSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAIFARA +DRPRRIDVDLAMGEAARTAV--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. 11-1-2 TaxID=1851167 RepID=A0A222TB22_9ACTN +---IEKRIAEVFAEADAEARLHAVDIDPGREL-GLGVDDQVVIASVFKILLVLEFARQAD +AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL +DTVRLLAAELGLDRTRIVGGPRELLEVLDPGHTTSSTPRDITTLLGLIWRDRAGSPAACA +LVRELMSRQVF-RQRLASGFPGDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART +ASAARTAVDAAIGRAARLAV--- +>[subseq from] serine hydrolase n=1 Tax=Nocardia niigatensis TaxID=209249 RepID=UPI000314DF16 +---------EIFRTAGVEGRVHARCFDCGGEF-GWAADEPVVLSSVVKVPLVLEFARQVA +AGQLDPSDRVRATAADRLGGVGTAGCHDDVEFSLRDAAWFALTVSDNTAADLLFDRV-GV +DNVRSLARELGLTGTRIMGSLRDILYAVDPLRTTAGTARDMTRLLWLIGEDRAGAPEACR +FVRDLMRQQVY-GHRLPSAFPPDTDIWSKTGTLP-GIRNEIGVVGYPDGSRYAVAVFTVS +HSGRQPVVDRAIGAAARLAVE-- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006BF6A39 +-qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA +NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNAATNALIDLL-GF +DAINQWSQRARLAASRLQRRMMDTAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter ginsenosidivorans TaxID=398053 RepID=A0A5B8V2B4_9SPHI +-kKLTLQLQDAVKGFNGQVGIYVKNLKTGKYA-EINADTLFPTASMIKVSIQCGVMDKIE +KGELQYNQKLIYRDSLLYPGEDILGSFKDKDIELSKAVLLMITMSDNTASTWLQKIV-TG +EYINNWLEQNGFKVMRVNSRVKGREKIRARYGWGVSTPREMCRLFTMIRDGEAVSPAASE +RMYRNLGRIFW-DDKALSQIPPYVNTASKQGALDE-SKSETVLVNAPHGD-YVFSIITNN +NKDQDNEADILIRKVSALLWHYy +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007EE5DBF +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVVMNDLGQALYR-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000FCB2F6C +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVVMNDLGQALYR-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007BC614D +---VTDLVAQATKGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. An77 TaxID=1965655 RepID=A0A1Y3TTL1_9FIRM +--TLEKRIAAELYSYHGQMSVFVDDL-QGHTV-EMGADEPFETASTIKAYILAALYLQAS +RGKASLEDTVTYRPEHFVDGSGMLRAGVGAALKVKDAATMMIICSDNIATNMIIDYL-GL +EEINRCIQELGFEHTVLHNPLH-FD---RYDKLGTTTPRDYAGLFARVARGTLVSREASA +DMLAIFRSQHY-NTMLTGNFPPYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKN +FDD-------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces triticisoli TaxID=2182797 RepID=UPI000DD9C6E6 +-----------------------------REV-AVGADTPVVIASIFKVLLALEFARQVV +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNTAADLLLARV-GL +DTVRLLAEELGLERTRIVGGPRDLLEVLDPRHTTASTPREITRLLQLIWSDAAGPPEACA +FVRDLMGRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVARYPDGAHYAIAVFVRT +HDASRPTVDAAIGRAAGI----- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. NRRL B-16802 TaxID=1415541 RepID=UPI0006AE8055 +--------------------LTVGQLGGGREV-GVRADEQVVIASIFKILLVLEFARQVE +AGQLDPTERILVTADDRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLTRTRVLGGPRELVEVFDPLQTTSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAIFARA +DRPRRIDVDLAMGEAARTAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Haloactinopolyspora alba TaxID=648780 RepID=A0A2P8E5P7_9ACTN +--ALRGELDALARRSPGRWAFSVRE--SGRPVaSVSGSVVMPAASTVKVALLALVLVDVA +AGERSLDDPLPVP-DRRAGGTGVLDLMPSVRLPLGEALELMIGVSDNTATNMVIDAL-DL +DEAGRRIVALGASSTLLRRHLMDTDAA-RAGRDNVTTADDQALILDRLAGPDLLPQPWRR +YALDVLGRQQF-NDRIPAGVGPDVRCAHKTGELP-GVRHDVGVLEFDGR-SVVLAALGSE +----------------------- +>[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=uncultured Faecalibacterium sp. TaxID=259315 RepID=A0A1C5M2W9_9FIRM +--TLEKRIAAELYSYQGRMSVFVDDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAN +RGKADLEEDITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA +AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE +FHD-------------------- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007EB3325 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GER--TAQMVAMNELGQALYR-- +>[subseq from] Serine hydrolase n=1 Tax=Edaphobacter sp. 12200R-103 TaxID=2703788 RepID=A0A6B9YLR0_9BACT +--SLQQSLAAIAATHKGHVVLYAKQLNTGKVV-ALDSDQPVQTASVIKLAILFEAMEQVR +DGKAHWNEKLTLKKDDGVSGSGVLTFFDTPLLTLKDVLTMMVIVSDNTATNLAIDRF-GT +SAVNARIAWMGLKDTHLYKKIGKPATDQPKFGLGKTTAHEMETIMERIGRCELGKPGEPA +QPGDIMLRNQFYRNTIPRYLEEGSGIASKTGSLN-AVRNDVAIVAGKDG-PIIISIFTYG +NETADNEAEIIIARLARKIVEAw +>[subseq from] serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=UPI0012DC9421 +--TLEKRIAAELYSYQGRMSVFVDDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAS +RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA +AMLGIFRQQHY-NTMLTHDFPQFLWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE +FHD-------------------- +>[subseq from] Beta-lactamase n=2 Tax=Candidatus Woesebacteria TaxID=1752722 RepID=A0A0G0KXR1_9BACT +--EITSAFKDKTKDLSGIYGLYVINLNNGASF-GVNENEKFQAASLIKLPVMAGMYIEDD +KGNIDLDEKYTLRTSDKVKGAGSLYSKPAGYITYRNLVELMGKQSDNTAFNIFRRIL-GE +EKIGEIIGNIGMMDTSLN--------------ENITTPRDIGIYFEKLWRGNIVNDLSRD +ELLDALTDTIY-EDWLIKGIPKEVRVAHKYGRELH-VVNDAGIVFAE--KPFVIVIMSKG +VV--EAEADKAFPELTKIVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Megasphaera sp. An286 TaxID=1965622 RepID=A0A1Y4CIE3_9FIRM +-------------QDKAAVSVYCRPLDGGDDF--FYRDRVMPSASLIKVPIMACVFRQEK +EGQLSFDTTYPVYG--GVEGGSFYGLPEGTEVSLRTLVFHMIVESDNTCTNMLIDVL-GF +DAINEEIRRQGMEHTLLRRKMMDFEAA-RQGKENVTSPGDMGRLFLRLASGTCVDGRRDE +AMRAILAQQED-NCILPAQIPNTVAVEHKTGELD-GIYHDCGIVWKQGR-PYVCCLMADG +IV--------------------- +>[subseq from] serine hydrolase n=1 Tax=Haloactinopolyspora alba TaxID=648780 RepID=UPI000D0DCB31 +--ALRGELDALARRSPGRWAFSVRE--SGRPVaSVSGSVVMPAASTVKVALLALVLVDVA +AGERSLDDPLPVP-DRRAGGTGVLDLMPSVRLPLGEALELMIGVSDNTATNMVIDAL-DL +DEAGRRIVALGASSTLLRRHLMDTDAA-RAGRDNVTTADDQALILDRLAGPDLLPQPWRR +YALDVLGRQQF-NDRIPAGVGPDVRCAHKTGELP-GVRHDVGVLEFDGR-SVVLAALGSE +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Halorussus sp. ZS-3 TaxID=2650975 RepID=UPI001301802F +--------DSYREKLDGRLGVFLGFPDGPDDFyRRAATTQFASASVVKLPVLYALLAKYD +GRLSELDAPREIAPENRVAGSGVLHLL-SATPTLRDLARAMISISDNAATNELVDEL-GM +DRIESAAADVGMTDTRLRRKMMATLGWPDGEPANATTPLDCARFFADFHSEATLSAAAYD +EMAVPLEAQKH-AMKFPRYLPRDATVVHKTGELPE-AALDTGYLRPPDGNPLVFAVLADE +LT-TGADGADAIAEIGEAVYTWf +>[subseq from] serine hydrolase n=1 Tax=Hamadaea tsunoensis TaxID=53368 RepID=UPI0003FA5228 +------------TSTGGTVSIWAGPIDGPPAY-AWNEDAGHYAASTMKVAVMAAAFRAAE +RDELDLGAQVDIVNRFTSAGAPAYTSRIGGRADLGWLIERMIVRSSNLATNLVIEQLGGT +AGVNEVWRAVGAKRSVTGRGIEDAAA-REAGVTNTVTAADLAALFSALARHDIATTESCD +AMLRILLAQEY-RDDLPAGLPEGTPVAAKNGWVT-GVRHGAAVVLPDDEPPFTLVICTST +DL-GEAEGAALVARIAEAAWR-- +>[subseq from] Serine hydrolase n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A6B2UPX9_9ACTN +--AVADRIAAAFADAGVDGVVHAVDIDRGTEA-GYEPDRLVSTASVHKLCLLLALHRLAA +AGRIDLTEQVECAVEGRTPGTGLAAMLDPSRLSLRDLAYLMIAVSDNAAADLLLARV-GL +EEVNRTTEALGLRLTRAVESFGATQEALDPTHGNRSTPRELTRLLRALWRDEFLPAAHGA +AVRRLLGLQVW-PHRLASGFPDDVRVSGKTGTLPT-MRAEAGVVEYPDGGRYAVAVFTRA +ADHVLPAADAVIGVVARVAVD-- +>[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI00142242AF +--ETSAQIAEIFADAGATGFLHAREIGDGPEV-TVGADDPVVLASVFKILVLTAYVRAVA +AGELDPTARTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDVIYHRL-GT +EAVDRVIADLGLADTRLIGCCEDLFAAVQPLRTSHSTPRDVTTLLNALWTDTAATAEACR +QARDIMALQIW-PHRLTAGFPSDVRIAAKTGTLPT-WRNEAGVVTYPDGRRYAVAVFTRA +ASL-ADRQPLVDASIGRAAF--- +>[subseq from] serine hydrolase n=1 Tax=Faecalibacterium sp. Marseille-P9312 TaxID=2580425 RepID=UPI00122C7A99 +--TLEKRIAAELYSYQGKMSVFVDDL-HGHTV-EIGADEEFETASTIKAYILAALYLQAG +RGKASLEEKITYKPEHFVDGSGMLRAGVGASLKVKDAATMMIICSDNIATNMVIDYL-GL +ATINACIREMGFAHTVLHNPL---HFDIYND-LGTTTPRDYASLFAQVAKGTLVSAEASA +EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD +FHD-------------------- +>[subseq from] serine hydrolase n=1 Tax=Pseudoflavonifractor sp. Marseille-P3106 TaxID=1871015 RepID=UPI0009BBA247 +--ELNAYLHREIEAFPGQTSLLVSDPLSPEPLhAWQETLRVPSASTIKTPILLTALEQVR +QGMLSLTDPMTVSPDCVLPDTEVFDR-GESVYSLGELLYWMIVESDNTATNVILDAL-GF +DAVNEYCAMLGLENTLCQRKMLDFAAA-QAGLDNFTSAADQRRLFSLLHGGQILNPGLRK +IALSILCRQRS-MDCMLRYIPDAVEVAHKTGGLN-GVAHDCGLFLLPRR-PLFVGIFTWD +GPDGDPGQKRYIGRLAKAVYDFy +>[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536DFC8_9CHLR +------------------------------------------------------------ +------------------------------------EVGAMIAVSDNSAANQIVDAI-HP +QAVNDTLGRLGLGGTHFMNLFSDARSA-ASPGLNQTTPANMAHLLELIATDQIVSPQVSA +DIRTLLGRNVD-RSKLVRLLPPDARVEHKSGWYE-GVANDAGIVTVDRVTRWVIAVFSEN +LP-DAETGNQLVAAISKAVYDAw +>[subseq from] serine hydrolase n=1 Tax=Segetibacter koreensis TaxID=398037 RepID=UPI00052674F2 +-kKLTRQLEKLVEGFNGQVGIYVENLKNGKSA-AINPDTLFPTASMIKVSIQCGLMDKIE +KGLLKYNQKLVYNDSIVYPGEDILGSFKNNDIQLSKVALLMITMSDNTASRWLQNLV-GG +DYVNNWLGENGFINMRINSKVAGRENMYNTYGWGVTTPREMCRLFTMIAKGQAVSEAASE +RMVRNMGRIYW-DDKALSQIPPYVHTISKHGSLNE-SRSETVLVNAPHGD-YVFSVITKN +LKTPDNEAIVLIKNLSSLLWQHf +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis lurida NRRL 2430 TaxID=1460371 RepID=A0A2P2FUG8_9PSEU +--RIADEIEAVFAAAGARGFVHAREVGDGPEV-AVGADDPVVLASVFKIPVALAYAGEVA +AGRLDETERTLVTARYRIGGVGTAGCADDVEMSWRDLAHFMLTMSDNAATDLVYHRV-GQ +EAVDRVLADLGLVRTRLIGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACD +RVRKIMAQQIW-PHRMSSGFPAGVAVAAKTGTLP-AVRNEAGVVSDVDGRRYAVAVFTRA +ESDRLPAVDASIGTAARLAVDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora coxensis TaxID=356852 RepID=A0A1C5JC13_9ACTN +--AVQQRIAQVFARAGGSLHVVPVDGPDGREI-ALDADRRTVIASVFKILLVLEFARQVA +AGQLDPTERVLVTAGDRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GA +DVLPMLAAELELGRTRVRGGPRDLVEVFDPDRTSSSTARDLTRLLTLIWRDRAGPAVACA +TVRELMSRQLV-RTRLASGFPPGVRVVSKTGTLP-GLYLDAGVAEYPDGARYAMAVLVRA +AHTHRTDVDLAMGEAARIAVQ-- +>[subseq from] serine hydrolase n=1 Tax=Runella limosa TaxID=370978 RepID=UPI0004905853 +-kKLTALLQQAIKGHEGNVGVYVRNLKTNKIV-EINADTLFPTASMIKVPIQCGLFDKIS +KGELKYNAILTYKDSLHYDDGIVGSLKDGAKIPLSEVVMLMETVSDNTGSLWCQALAGGG +KSINEWLDKNGFTATRVNSRTPGREANRTRYGWGQTSPREMAELIAMIRAGKAVSPDASD +RMYRNLTRQYWDGEGL-SQLPPEIKTACKNGAVNR-SRSEAVLVHAPHGE-YVYCVITKN +NKTSNNAGYVLLRKVAKALWTYy +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000B3CDCA0 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGNLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQMVAMNELGQE----- +>[subseq from] Beta-lactamase class A n=1 Tax=Pontibacter chinhatensis TaxID=1436961 RepID=A0A1I2S8J3_9BACT +-dELSQQITTTLGAQEGTFAVAFKDLQTGKEL-LLSAQESFHAASTMKTPVLIEAYKQAS +EGRFSLSDSILIHNESIVDGSLYSYTLIGQKRPVSELLYKMIIQSSNLATNLIIEEL-DA +KQVTLTMRELGAQAIQVLRGVEDKK-AYERGLNNTTTAYDLMLLFEQIAAGKAVSPEASQ +EMVRILLDQRH-REIIPARLPEGVKVAHKTG----------------------------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535AJB8_9CHLR +--DLVAHLDQLSEAFPGGVGLWISDPNASKPLyTRNPDEQVITASLYKLGVLMETERRVE +AGELHYNDIITIQPEDVSEDGSF--EAVGTELTIDQALEAMITISDNGTAQALWHLL-GG +ANIDATLAKVGIPDFHV---------AFDSSEDNVATPRAIAQFFTLLAKKQLVSLAASE +RMLARLERQEI-NDRLPAALPDGVVVAHKTGNLL-GLAHDAGIIFTPSGPRIVVAMTWDA +YD---EDANAFIANVGALVYS-- +>[subseq from] Serine hydrolase n=2 Tax=Faecalibacterium TaxID=216851 RepID=A0A3E2TAI5_9FIRM +--TLEKRIAAELYSYQGRMSVFVDDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAS +RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGALVSKEASA +AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE +FHD-------------------- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535GF80_9CHLR +--DLVAHLDQLSEAFPGGVGLWISDPNASKPLyTRNPDEQVITASLYKLGVLMETERRVE +AGELHYNDIITIQPEDVSEDGSF--EAVGTELTIDQALEAMITISDNGTAQALWHLL-GG +ANIDATLAKVGIPDFHV---------AFDSSEDNVATPRAIAQFFTLLAKKQLVSLAASE +RMLARLERQEI-NDRLPAALPDGVVVAHKTGNLL-GLAHDAGIIFTPSGPRIVVAMTWDA +YD---EDANAFIANVGALVYS-- +>[subseq from] Secreted beta-lactamase n=2 Tax=Streptomyces violaceusniger TaxID=68280 RepID=G2PAF4_STRV4 +---IEKRIAEVFAEADAEARLHAVDIDPGREL-GLGVDDQVVIASVFKILLVLEFARQAD +AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL +DTVRLLAAELGLDRTRIVGGPRELLEVLDPRHTTSSTPRDITTLLGLIWRDRAGSPAACA +LVRELMSRQVF-RQRLACGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFAGT +ASAARTAVDAAIGRAARLAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFCSPLOWO2_01_FULL_48_11 TaxID=1798395 RepID=A0A1F6ARK2_9BACT +-eELQKKIQAQIGNTWKNYSIYVKDYTSDFSM-GINDTVIFTAASVNKIPIIAALYWQVQ +NQAIDLDTSVTIQASDVQYGTGTIQSPPGSTYSVKTLAKLMMQQSDNTAAYILANYTVGL +DTIQTLVNRWGLTQTDIIN--------------NKTSNKDMEILMDKIYTGKITNTAYTQ +EMLAFFKDSDF-EDRIPALLPKGTTVYHKIGTEV-GVMHDAGIVHQGNL-TYYIGIFTSD +VS-DEPTTIKLIAEISKAVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium paraputrificum TaxID=29363 RepID=A0A173Z5W8_9CLOT +-----KEIKRYLESRIGTYGFFFEDLSSGFIY-GYNENVQMVAAGCMKLPIAVSLIKAVE +DKKVDFMDKIKIEKEDKVYGTGIIHEFNEREYTIFELLVAMLIQSDNTAANKIIDII-GM +DNINSNIKEMGLKNTILNRKTSDERQS-KEGVENITSAYDLSKIWKHLHNATYLNRDNST +MLVDILRRQQI-KNKLALYIPDDYEISSKTGDKK-GVENDTALIQLPKGN-FVFTVLSTS +VPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora parva TaxID=1464048 RepID=UPI0004BFF44D +---VQERIEAIFAAAGVTASMHAVDLDSGREV-GVRADEQVVIASIFKILLVLEFARQVE +AGQLDPTERVLVTAADRLGGWGLAGCVDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPILAVELGLTRTRVLGGPRDLVEVFDPARTTSSTAREITRLLTLIWRDEAGPPAACA +MVRTWMARQLF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA +EQPRRIDVDLAMGEAARTAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces qinglanensis TaxID=943816 RepID=A0A1H9T153_9ACTN +--------------------VAELH-RPSARV-TVDADGLALMGSVYKVPLMVAYCRQVD +AGALDPRQRLTLSAGDRLPGPTGLSLLRDEVMSLRDLVVMMMSISDNAAADAVLRQV-GT +AAVEETCAALGLSRTRLDGGAAGSLAVYDPAWAAATTPAEMAALLRAVWRDEAASPGSCA +FMRATMGLQPW-QHRLAAGFPDEVAVYGKTGTFG-AMRHEAGVVELADGRGYTAVVFTQA +ARADLPRADAVVGAAARTAVEH- +>[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1H6GHC0_SELRU +-----ADLQVLLEERMADYAIYYLRPDLEQEP-FVQSSRQQQPASMIKLFVMAKAMEDVK +AGRMSLEEPVTLQKEDVVGGAGLTIYNLGTPITVRELITLMIQASDNTATNALITKL-GM +GEINAYLEREGYHDTKINHKMMLQKVVVTKLPDNLSSVQDVGTLFTRLYKHECVGPQEDE +IMIDILKGQED-TACFNAALP-DWQIAHKTGEIS-GLFHDGGIFYGSEGN-FVLVIFCEK +YA--------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora flava TaxID=95161 RepID=A0A1I6UI74_9PSEU +-------------EFPGRVGIASWDLREGVPV-LRGAEVEKHSASTIKVLVMIAALRAVA +DGRLDLDRLVELPRERIRGTGVLFEMPSVAAVSLRDLIALMIVVSDNGATNAVIDEV-GF +PAIADCIADLGCTGTRVERHIMDTES--PG--LLQTTALDQARVMAALAGGEALPARQTE +HALDVLARQQV-VDRIPLRLPENARCWNKTGEIK-GLRHDVALLSTDDTPQVVLAVLIDR +LTD-------------------- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora echinaurantiaca TaxID=47857 RepID=UPI000B5AD72C +--------------------------DGGREV-AVRADEQVVIASIFKILLVLEFARQVV +AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DVLPMLAAELGLSRTRIVGGPRQLAEVFDPERTTSSTAREITRLLGLIWRDEAGPAEACA +MVREWMSRQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARM +ADTRRIDVDLAMGEAARTAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridium sp. BL8 TaxID=1354301 RepID=T0PN06_9CLOT +-----KEIKRYLESREGNYSFYFEDLKGGYTY-GFNENVKMPAAGCIKLPIAMALLKEVE +NGSVSLDDLVSIGDEDKVSFFGIIHEFSEKQYTLKELLVAMLIQSDNTAACKIINTL-GM +NRINNIINNMGLKSTKVNKYPSEIK--LEDNNENITTSYDLSQCFKILNNNTALNKEHSK +LILDTLKRHQL-TTRIPFYFPREIKTANKIGTLES-VENDTALLNISKGD-FVFTVLSNN +LP-TNVYGITTIARTGKMMFD-- +>[subseq from] Beta-lactamase n=2 Tax=Acetobacter TaxID=434 RepID=A0A149R674_9PROT +---LAQIMAKTVSKQPGHFAVYAARSGQAPDV-CLNCDDLINAASTMKLFVLDTAYEAFT +KGTLHPEDTIVVHNHSLVGGSFALYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV +LPIRSVVKAQGLIGIVFGRMIEDFDAN-DQGIRNQVSARGLGDFLQKLDSGKIVGKAQSQ +SMIQIMLGQKF-NDIIPPGLPASTPVAHKTGWVD-GVRNDAAIVTLPDGKRYILVVLTSG +LP-DEQAGIRVLNTLSHQAYEYf +>[subseq from] serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=UPI0012DF3BBA +--TLEKRIAAELYSYQGRMSVFADDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAS +RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA +AMLGIFRQQHY-NTMLTHDFPQFLWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE +FHD-------------------- +>[subseq from] Beta-lactamase n=1 Tax=Terrisporobacter othiniensis TaxID=1577792 RepID=A0A0B3VXY7_9FIRM +-------IINKLKNMKGDVSFYYKNLVTQEII-KYNEEKPMLAASVIKLTVLVECFNQIK +KDIIRKDDIFITKEEDKVPSCGALNYMRENLITLEDLYVLMIILSDNYATNILIDKL-GI +DNINKTIKEIGLKNTVLNRKMFDSDKA-ALGLENYISAGDIAYLLEKMYNKELIDEKSSE +EMINILKNQRL-NSKVPFFLQPKVNIAHKTGEDTN-ITHDVGIVFD--KEPFIVCFCGNN +V--NVPEYERLMQDVT------- +>[subseq from] serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=UPI000E3F1D9C +--TLEKRIAAELYSYQGRMSVFVDDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAS +RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSREASA +AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE +FHD-------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora echinaurantiaca TaxID=47857 RepID=A0A1C5JQ90_9ACTN +--------------------------DGGREV-AVRADEQVVIASIFKILLVLEFARQVV +AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DVLPMLAAELGLSRTRIVGGPRQLAEVFDPERTTSSTAREITRLLGLIWRDEAGPAEACA +MVREWMSRQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARM +ADTRRIDVDLAMGEAARTAV--- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000930E809 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTAAQ-KAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] serine hydrolase n=1 Tax=Microbacterium maritypicum TaxID=300020 RepID=UPI00124B162B +--------ADIFADAGATGFLHAREIGDGPEV-TFGADEPVVLASVFKILVLTAFVRAVA +AGELDPTERTTVTARYRIGGVGTAGFADDVEVSWRDLALNMMSMSDNAATDIIYHRL-GG +EAVNRVITDLGLRSTRLIGCCEDLFAVVQPLRTSHSTPRDVTTLLNALWTDTAAPAEACR +QARDIMALQTW-PHRLTAAFPGDVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTQA +ASLV-DRQPLVDASIGRAA---- +>[subseq from] Beta-lactamase n=3 Tax=Lactobacillus TaxID=1578 RepID=A0A165QRY5_LACPN +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0003987444 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] serine hydrolase n=1 Tax=Spirosoma terrae TaxID=1968276 RepID=UPI0013D2C2EA +-qSLDQQLQTAIAGFQGDVGIYVHNLRTDQRV-AINADTIFPTASTVKIPIQCGLFDKIH +KGELSYNQELVYKDSLHYDDGIVGSLKDGAKIPLSHVVMLMETISDNTGSLWCQALAGGG +TAINNWLATNGFQETRVNSRTPGREAYRSRYGWGQTTPRELAQLLTYIRQGRAVSPDASE +EMYRNLGRQFW-DHNGLSQIPSSVKAVTKNGAVNQ-ARSEVVMVHAPHGD-YVYCVMTKN +QKERTNEGSTLLRNVAAILWHYf +>[subseq from] Beta-lactamase class A n=1 Tax=Jiangella alba TaxID=561176 RepID=A0A1H5PX93_9ACTN +---VEGELKDAFAAAGVTGFLHAADVGSGAEV-GVEPDAPVVTASVFKIPVLVELCRQFA +TGERAPADRLRVPAGGRTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR +EKINAGTAALGLTGTVLEEDCAGLFRVLDARTTNRSTPRETTTLLRRVWTADGLPAAACD +EIRRILALQVW-PHRLTSGFPDDVRVSGKTGTLSH-VRNEVGVVEYPDGGTYAVAVFLRL +PGAENPAADAVIGTAARIAVDH- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007D8DEC5 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVVMNDLGQALYR-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536QH90_9CHLR +--DLVKQLDGLVSSFPGGAGIWIADPTVATPLfAHDAEEQVIAASLYKLGVLAEAERRVD +TGELHYADTVTIEPDDITADGSF--EYAGTELTLDEALEAMITVSDNGAALALWHIL-GG +ANIDATLEKAGISNFHVA---------FDDTEDNWATPHAIGTFFTLLAKRQLISPAASD +RMLARLERQQI-NDRLPAQLPGGVVVAHKTGNLS-GVTHDAGIIYTKTGPRVVVAMTWDA +LD---EDAANFISSIGSLVYS-- +>[subseq from] Putative beta-lactamase n=1 Tax=Prochlorococcus marinus (strain MIT 9313) TaxID=74547 RepID=Q7V6M1_PROMM +--TLSNRWRELAKQQDLQASAFLLVLDDGRYA-ELSAETALPAASSIKTAILLVALELID +SGQLSWNEPLKLTKEIIGGGAGWMAKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGK +DVLNARFNALGLSSTVVNNWLPDLQGT------NTTSSHDLARAIALVDTGKALSPRTRD +LFREAMSTSVS-NRLLPGGFLKGYRIYNKTGDIGI-AYADAGLIELPDGSRAVAGFMVKG +PFND-PRSTELIRDMAAAM---- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacterium sp. S111 TaxID=2483795 RepID=A0A4Z0IXN7_9MICO +---LDTAIERLEDELGITCFVHARDLDDSAAV-GVREDEPVVTASVFKLPVLVEACIRMS +TGEVPAERRIVLGPEDFPVGSTGLAVFSDAVVSFRDLCLSMMTVSDNRATDVVMDIL-GR +ARVNARMRELGLTSTVIEGDCRHLFDTLDPGRTNRSTPAETTTLLAALWRDEGLPASACA +EARRILGLQVW-SHRLRRGFSDEVTVSGKTGTLPY-IRNEAGVVEFPDGGRYAVAVFLRT +PSPRGPRFDDAITDLAAAAV--- +>[subseq from] serine hydrolase n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=UPI0006903838 +-----ADLQVLLEERVADYAIYYLRPDLEQEP-FVQSSRQQQPASMIKLFVMAKAMEDVK +AGRMSLDEPVTLQKEDVVGGAGLTIYNLGTPVTVRELITLMIQASDNTATNALITKL-GM +GEINAYLEREGYHDTKLNHKMMLQKVVTTTLPSNLSSVQDVGTLLTRIYKHECVGEQEDE +FMVETLKGQED-KICFNAALP-DWQIAHKTGEYS-GTFHDGGIFYGPEGG-FVLVIFCEK +YA--------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A0M7ICJ9_ALCXX +-qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAVA +NDRYALEQPLALPACGGRAGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWSQRAGLAASRLQRRMMDTAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Beta-lactamase class A n=1 Tax=Desulfallas gibsoniae DSM 7213 TaxID=767817 RepID=R4KK74_9FIRM +---LQNQITGYLDKQPGIYGLYFIDVKSGQEF-GYNSHTVFHAASTFKLPMNLYLYLAAD +HGQINLAEQLLFTDKHLEGGTGILQNKSPGEYAVAQLADYSILYSDNVATNILLDRL-GK +ENVKEFMRSMGGQVVD--------------NEQNITCPYDLALYMRQALH--FAGQPAGE +KLLNNLFDNKL-KDRIPAPLPPDIKVANKIGTWPTNTYNDVAYVAHPEQ-PYILVVTCKD +TP-GYGEALAVIHHLSKLVYR-- +>[subseq from] Serine hydrolase n=1 Tax=Haladaptatus sp. R4 TaxID=1679489 RepID=A0A166TDP7_9EURY +----AGYVERYDDEIEGELGVFLGPTDDGEVVyARDETRVFQSASTIKLPVLYALYERYD +GQLDELDRPCPLSSENRVGGSGLLH-LLDATPTLEDLAAAMISVSDNAATNQLIDHL-GI +ESVNDEAARLGMERTRLARKMMATLEIPDDEPTNATTPLDCARFFADFVRRRTLSTEAYE +RMRVPLSAQKD-TSMIPRYLPYETEIAHKTGWLPT-AALDTGVLSVPDREPLVFSVFIDG +VGQNGADAADAIAEIGDAVF--- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007B55C20 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQMVAMNELGQE----- +>[subseq from] Serine hydrolase n=1 Tax=Gordonia alkanivorans TaxID=84096 RepID=A0A3T0UVQ5_9ACTN +--RIDRNVAEILADAGCSGWLHATTIGSPQISySYDADAPVVLASVYKLAVLISLCRSAD +RGEIDLTSPVTVDPTRWAQPTGLAALRDPITLSRRDLATSMMTVSDNVAADVLLDEI-GL +DRVREDLIGLGATSTRIVGGVAELHEAYDAAYSSSSTPRDCTTLLSAVWTDRAASSVMCA +FIRDTMRRQVF-TARLASGFPRRVTVAGKTGTLV-AIRNEIGVVEFPGELPVAVAVFTMS +ARPSLPQVDRAIGEVARTVVT-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium baratii TaxID=1561 RepID=UPI0006BABCF9 +-----KEIKKYLESRIGTYGFFFEDLNSGFVY-GYNENVQMVAAGCMKLPVAMALIKDVE +LGKVTFMDKIRIDGADKVYGTGIIHEFDARDYTIFELLVAMLIQSDNTAANKIIDIV-GM +ERINDYLKEMGLKNTVLSRKTADERKE-KPKVENLTTAKDLSMAWKILYDATFLSKENST +MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKP-GVENDTALIQLSKG-SFTFTVLSMS +IPNS-VYGTVTLAKSGKMMWD-- +>[subseq from] Beta-lactamase, putative n=2 Tax=unclassified Clostridium TaxID=2614128 RepID=G7LZR6_9CLOT +------EIKRYLESRIGTYSFFFEDLGSGFTY-GYNENVQMTSAGCMKLPIAVSVIRYVE +DGNASFLDKIKIEEEDKVYGTGILHEFDNREYTVFELLVAMLIQSDNTAANKLIDIV-GM +DRINDDIEAQGLKNTKLNRKTSDERAA-STGVENITSALDLSKIWKHLYDGRFLSEKNSK +MLIDILQRQQM-KNKLALYIPDDYEISSKTGDKTS-VENDTALIRTEKG-SFTFTVLSMG +IPNS-VYGTVTLAKSGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Planctomycetes bacterium K2D TaxID=2527962 RepID=UPI00118B6677 +-------ILDLAQSTPARVGLAVESLDGAWSY-SVLPDEVFAQASAIKVPILWELHRAAA +AGELSLDERLTVDPANGAGGCGMLQNFLPGAMALGDLGVAMIVLSDNVATNLLIDRL-GF +DAVNALLVSQGAKQTRLRRKMIDPEA-RKAGRENTSTPAEAVRLMRRLHDAEGAGDPVAA +AVLKVLRLRKE--SPVTTVLPSDTRLATKPGMLD-GLRTEWSIVEREGV-NYAMALMVDG +GDE--ILIDALVREIAV------ +>[subseq from] Beta-lactamase class A n=2 Tax=Granulicella sp. GAS466 TaxID=2485170 RepID=A0A3N1JWJ2_9BACT +--ALQRELAAIAASHHGRVALYATQLNTGKRV-GLDADTPVQTASVIKLAILFEAMEEVR +AGKARWDEKVTLAKGEAVGGSGVLTLLDTPVLTLKDVLTLMIIMSDNTATNLAIDRF-GV +DAVNARIGWLGLKDTHLYKKIMKPATDQPKFGLGKTTPREMAVVMERIGRCRLAGPGECE +VGLK-MLRNQFYRDTIPRYLETGSGIASKTGSLN-AVRADVAIVAGKTG-PMILSIFTYD +NATADNEGEVTIARLAKAIVEAw +>[subseq from] serine hydrolase n=1 Tax=unclassified Rhodococcus TaxID=192944 RepID=UPI000B9B36E5 +--TTDEQLRAVFADAGCRGWVRAERIDGTGTVvDYEGDDPVVAASVWKIVLLVATARAFD +EGSLTATDSVRLVPAQCSPPTGIASFADPVSMSWRDIARSMITVSDNAAADALLGAV-GL +DAVARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSVWLGTAASPAQCR +YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA +ARMDLPLVDQAIGHAARIAV--- +>[subseq from] Beta-lactamase n=2 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A0R2G987_LACPN +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetia bacterium TMED53 TaxID=1986839 RepID=A0A1Z8SC05_9BACT +---LQSQIENRIAQFEGVVGVHYHHLGSGEEI-SIRADETFPTASLVKLPILFALLDRVS +KGELDWHEKRTYKIARRYAGEDLLASFQDGEIALSKLADLMIRYSDNTASLWCQELAGTG +LTINRWLQQNGYPNTYVNSRTPGREDDYKQWGWGQTTPREMTRMVESLYSRECIGSPWDE +LMLKLMNSSYW-REEMLSAFPPEVTVYSKQGAVNR-SRSEVILAMSPSG-PFSLCVITKE +QRDT------------------- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia vulneris TaxID=1141657 RepID=A0A0C1BBT9_9NOCA +-----------FRKAGVQGWVHARCFGCAGEN-GLDADEPVVLASVVKVPLVLEFARQVA +AGQLDPADRVRVRAADRLGGVGTAGCFDDVELSLRDAAFFALTLSDNTAADLLFDRV-GL +DNVRSLVRELGLTETRITGAPRDIVQALDPRRSTASTPREMTRLLTLIGQDLAGSAQACQ +WVRDVMREQVN-WYRLAAAFPPEAQIWAKTGTLP-GVRNEIGVIEYPDGSRYAVAVFTRT +ESQRLPEVDRAIGAAAVAAID-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536AR16_9CHLR +--DLVKQLDGLVSSFPGGAGIWIADPTVATPLfAHDAEEQVIAASLYKLGVLAEAERRVD +TGELHYADTVTIEPDDITADGSF--EYAGTELTLDEALEAMITVSDNGAALALWHIL-GG +ANIDATLEKAGISNFHVA---------FDDTEDNWATPHAIGTFFTLLAKRQLISPAASD +RMLARLERQQI-NDRLPAQLPGGVVVAHKTGNLS-GVTHDAGIIYTKTGPRVVVAMTWDA +LD---EDAANFISSIGSLVYS-- +>[subseq from] serine hydrolase n=1 Tax=Sporosarcina koreensis TaxID=334735 RepID=UPI0009E4B35F +-tQLEQQLSLLAAGSTGNVSVCVRT--PDGTI-AIGADDVKRSASVLKVPIAMACLAAVD +RGELDLDTRLPIHE--PVGGSGVLAYMSGFTLTLLNAITLSIIVSDNTAANLVIEHT-GL +DRIQAFFDEVGAAGSKLTRKFMDYE-ALALGLENFATARDMVRFLECLDPSKHLSLKSKQ +QLKTIMRDQQL-IDKLPAYQPETLIIGNKTGTLP-GTEHDIAYFEND-RMRVDLAALTTD +WQYN-HDGQQTIARIGRLIIDY- +>[subseq from] serine hydrolase n=1 Tax=Nocardia jejuensis TaxID=328049 RepID=UPI0009FCBBFC +--------DEIFRKAGTRGWVHARCLDCDAEF-GSGADEPVVLSSVVKVPLVLEFARQVA +AGQLDPTDRVRATAADRLGGVATAGCADDVEFSLRDAALLALTVSDNTAADLLFDRV-GV +DNVRSLVRELGLTHTRIAGSQRDILEALDPLRTTASTPRDMTLLLSLIGRDRAAPEQACR +WVRDLMREQFS-GHRLPSGFAADVRTWSKTGTLP-GVRNEIGVVEYPDGSRYAIAVFTAC +DNQRQPEVDHVIGVVARQ----- +>[subseq from] Serine hydrolase n=1 Tax=Williamsia sp. 1135 TaxID=1889262 RepID=A0A1X1AWD4_9NOCA +-----QRLREIFADAGCAAWLHARTIGPEREF-GWYADDPVVMASVYKLPLLAALCVRAD +RRDINLRDTVTVDPRECAEPTGIATLHDPITLSWRDLAVQMMVVSDNAAADVILAEV-GL +GGVREILDGAGLHSTHVVAGMAQVQQAYDPALTGATTAREATCLLDLIWTDRVASAGSCD +FIRTTMRKQAW-KQRISSGFPLGATVAGKTGTLG-AIRNEVAVVEYPGEHPVAVAVFTHA +ARLSLPTVEAAIGQAARVAVN-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007C2DD0B +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH +KNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. 14-2496-1d TaxID=2023146 RepID=UPI000B9BBA6F +--TTDEQLRAIFADAGCRGWVRAERIDGTGTVvDYEGDDPVVAASVWKIVLLVATARAFD +EGSLTATDSVRLVPAQCSPPTGIASFADPVSMSWRDIARSMITVSDNAAADALLGAV-GL +DAVARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSVWLGTAASPAQCR +CMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA +ARMDLPLVDQAIGHAARIAV--- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000931CE10 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIILDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535RLI2_9CHLR +--DLVKQLDGLVSSFPGGAGIWIADPTVATPLfAHDAEEQVIAASLYKLGVLAEAERRVD +TGELHYADTVTIEPDDITADGSF--EYAGTELTLDEALEAMITVSDNGAALALWHIL-GG +ANIDATLEKAGISNFHVA---------FDDTEDNWATPHAIGTFFTLLAKRQLISPAASD +RMLARLERQQI-NDRLPAQLPGGVVVAHKTGNLS-GVTHDAGIIYTKTGPRVVVAMTWDA +LD---EDAANFISSIGSLVYS-- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. 8F6 TaxID=2025606 RepID=UPI000B98FBE1 +--ALSQRWAQLAAAQGLQSSAFLLVLDDGRFA-QLQPDLALPAASSIKTPILLAGLEDFD +NGKLRWNEPLPLTKEVVGGGAGWMAKPVGTRFPFFEAATEMIRVSDNSATNLLIKRLGGK +TALNERFTAIGLPSTAVNNWLPDLEGT------NTTSSRDLARSIALVDTGEKLSPRARD +LFREIMGTSRT-NTLIPLGLLLGITAYNKTGDIGI-AYSDAALIQLPNGQRAVAAFMVKG +PFND-PRSADLIRAMAGE----- +>[subseq from] Uncharacterized protein n=1 Tax=Arsenicicoccus sp. oral taxon 190 TaxID=1658671 RepID=A0A0K1FEE8_9MICO +----------------------------GVVA-GWDADREVPAASLVKVLVLVAALREVD +GGRLSLDQTLQLPE-ERVGGSGALSLLPSVTLAVVELLRLMVTLSDNDAANLLLHLL-GH +DRVTRTGREIGLQHTQVARNLRDRAAA-ESGRDNTTTAADQAGLLAALRAGQVLGGASTR +LALALLAEQQH-AYGVTALLPDGVVRGSKPGDLP-GVRHDVALVETGGS-WATVAVTATG +MY-DERH---------------- +>[subseq from] Beta-lactamase class A n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A2N3U4X1_9ACTN +----EDRLAQVFAEAGCQGSVAVLDIDGPGQV-VLGGDELVVAASTFKIAVALELFCRGA +EGELDLAERVRLAPSQATPGQGFCIFEDEAEVSLRDLARMMVTISDNTATDVLIRRV-SV +PRIHARLAALGLDRIRLAGTIQEEFDSLRPGRITSATAGQMAALLRMIWRDEAGPAEACA +AVRSVLGQQRL-TRKIAAGFGDEVRVAAKSGTVPGCVSNDAGVVHFPDGSRFAVAVFTRP +TGPRPPQSDSVMGTVARLGVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Lentzea flaviverrucosa TaxID=200379 RepID=A0A1H9XXB9_9PSEU +--------------AGVEGFVHAREIGDGPEA-GHGADEQVVLASVFKIPVVVAYAAEVA +AGRLDETERTRVTPRYRIGGIGTAGCRDDVEMSWRDLALFMMTMSDNAATDVVFHRV-GQ +AAVDAVVA--GLPRTRILGCCEDLFAIVDPERTTSSTPREITTLLDAIWTDRAAAPEACE +RVRAIMAQQIW-PHRLSSGFPADVLVAAKTGTLPS-VRNEAGVVTYPDGRAYAVAVFTRS +QSLDNPSADAVIGRAGRLAVDQ- +>[subseq from] serine hydrolase n=1 Tax=Dyadobacter sp. 32 TaxID=538966 RepID=UPI0011ECFE9A +-tKLTRKIEIAMSGFKGSAGVYVRNLKTNRVV-SIHSDSLFPTASMVKIPILCGIFDKIN +RGEIKFAQELVYRDSLKYDNGVVGSFRDSTKIALPKVVHLMISLSDNTGSLWLQALAGGG +ETINQWLDVNGFPNTRVNSRTPGRKQGQAKYGWGQTTPREMAELITMIRNGKAISAEASE +RMYRYLGMQFW-DGEALSQIPPYIKTAAKSGAVNQ-AKSEAVIIHAPHGD-YVLCVTTKN +QESKDNEGYVLIRKISEIVWNHf +>[subseq from] Beta-lactamase class A-like protein n=4 Tax=Candidatus Levybacteria TaxID=1752719 RepID=A0A0G0NSM5_9BACT +--SLRSDVTEYTQKQKGSYSVYYNNFQNNSSF-GIDERQIIVSASVNKTPLIAVLYYLAS +KGEINLDSKITILEKDIQDTGSLRYEKPGGSYSLRNLAKLSLKQSDNTAAHVLGVRI-GM +DKIQKTIDEWGLTQTNMA--------------DNKTSNYDVYLLFRKIYNGEVTNAAHTQ +ELLSFFTDSDF-EDRLPALLPEGTIVYHKTGDAE-GGVHDVGIIKNGENA-YYLGVMTSD +IGEEEGEAKRAIAEISKIIFE-- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A162DUM5_LACPN +---VTDLIEQATNGLAGQTSVAVMPLAGSQSV--VVNNHAQRAGSLITLFIMVTAYDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANQRLISSKVDH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVRNRQGT-FIMTMMAAS +GER--TAQTSAMNDLGQVLYR-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI00071094F4 +---VTDLIEQATNGLAGQTSVAVMPLAGSQSV--VVNNHAQRAGSLITLFIMVTAYDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANQRLISSKVDH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVRNRQGT-FIMTMMAAS +GER--TAQTSAMNDLGQVLYR-- +>[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. NEAU-G17 TaxID=2293572 RepID=A0A372JN32_9ACTN +------------AAAGVRGFCFARDIDGDRAV-GVAPDAPVVLASVFKIPIALEYARQAA +AGRLDPTARYAVEPRFRDGGIGTSGCADPVEMSLRDLVLMMLTMSDNAATDVVLERV-GT +DAVNATLTALGRTRTHLVGGCAALLAVCDPARTTRGTARDIAELLAQIWRDEAGPPAACA +EVRAVMARQVW-PHRLASGFDDTHLVAGKTGTLP-GWRNEAGVVQTPGGGRYAVAVFTRS +TRPDHPEADRVIGTVARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI00083AC5F5 +-qHVDAALTPLLAATPARISLSLRDLDGGVVL-ARHADRVQPSASIIKVPILLALLEAVA +KGRYALEQPLALPASDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWNQRANLEATCLQRRMMDAAA-REAGRDNYTSAGDATAAFCWLLRDDSLPAPLRA +FALDVLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FT--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. 5K548 TaxID=2530386 RepID=A0A4R5BDC7_9PSEU +-----------EWDLPGRVGIASWDLRENAPV-LRGAEVEVHSASTIKVLVMITALRAVA +DGRLDLDAQVELP-ADRTKGTGVLFEVPSVPASLRDLINLMIVVSDNAATNAVIDQV-GF +TAIAECTADLGCTGTRIERHIMDTDA--PGV--LQTTALDQARVLTALAEGTALPPQLTA +HALTVLSRQQV-VDRIPLLLPENARCWNKTGEIK-GLRHDVALLSTDDTPQVVLAVLVDQ +LTD-------------------- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus alpinitundrae TaxID=468913 RepID=UPI001379599B +------------RGYAGEVGLHISALDGQLLA-THAADVVFPAASIIKVPLLLLALERVQ +AGALNLAERFELRAADRVGGAGVLHELGAGLPSLQDLLTLMIIVSDNTATNLVIEQL-GV +NAVNAWLDERGCSHTRLVGKLEQHNPAQRRGERNRTTAAEQARLLLGLWNGERLDPLHRE +LALSILGHQQY-RDILARPLPHDYRTHTKSGELG-GVHHDVGLLQLPRG--LCVTLLSRG +GS--------------------- +>[subseq from] serine hydrolase n=1 Tax=Microbacterium maritypicum TaxID=300020 RepID=UPI0004CE768B +--ETSAQIAEIFAGAGATGFLHAREIGDGPEV-TVGADEPVVLASVFKILVLTAYVRAVA +AGELDPTARTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDVIYHRL-GT +EAVDRVIADLGLADTRLIGCCEDLFAAVQPLRTSHSTPRDVTTLLNALWTDTAAPAEACR +QARDIMALQIW-PHRLTAGFPGEVRIAAKTGTLPT-WRNEAGVVTYPDGRRYAVAVFTRA +ASL-ADRQPLVDASIGRAAF--- +>[subseq from] Beta-lactamase class A-like protein n=1 Tax=Achromobacter insuavis AXX-A TaxID=1003200 RepID=F7SYA9_9BURK +---VDAALAPLLAATPARVSLSLRDLDGGIVL-ARHADRPQPSASIIKIPILLALLEAVA +GGRYTLGQPLVLPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIELL-GF +DEINQWSQRAGLTASRLQRRMMDAAA-REAGRDNFTSADDATAALCWLLRDGALPAPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] serine hydrolase n=1 Tax=Nocardia seriolae TaxID=37332 RepID=UPI0012BC236A +---------EIFRTAGVEGRVHARCFDCDGEF-GWGADEPVVLSSVVKVPLVLEFARQVA +AGQLDATDRVRATAADRLGGVGTAGCLDDVEYSLRDAAYFALTVSDNTAADLLFDRV-GV +DNVRSLVRELGLTRTRVDGSLRDILYAVDPLRTTASTPRDMTRMLLLIGQDLAGVPEACG +WVRDLMRRQVF-GHRLPSGFAPGTDVWSKTGTLP-GIRNEIGVVGYPDGSRYAIAVFTVS +HSGRQPAVDRAIGEAARQAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Microbacterium maritypicum MF109 TaxID=1333857 RepID=T5KJA7_9MICO +--ETSAQIAEIFAGAGATGFLHAREIGDGPEV-TVGADEPVVLASVFKILVLTAYVRAVA +AGELDPTARTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDVIYHRL-GT +EAVDRVIADLGLADTRLIGCCEDLFAAVQPLRTSHSTPRDVTTLLNALWTDTAAPAEACR +QARDIMALQIW-PHRLTAGFPGEVRIAAKTGTLPT-WRNEAGVVTYPDGRRYAVAVFTRA +ASL-ADRQPLVDASIGRAAF--- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000437A572 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQERYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Beta-lactamase n=1 Tax=Mycobacterium haemophilum TaxID=29311 RepID=A0A0I9ZS32_9MYCO +--EVSRQIQAVFTDAGCRGWLQARPVSTVEPAiNFRADEPVPTASIYKVLLLAAVARSFD +RGELDPSARVTIRPTDCTPGPTGFSTFIDPVVSWRDLARSMIVLSDNAAADILLAAV-GL +PRMDEIIDELGLASTHVIGGAAALYEIYDPDQTNATSAADSNTILAAIWTNTIASPHACS +YMRGVLAQQVW-PHRIKSGFPREISVAGKTGTIGK-IRSEVAVISLPNETPIAVSVFTHA +ARHSLPAVDRAIGTAARIAVT-- +>[subseq from] hypothetical protein n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0006C17615 +---VTDLIEQATNGLAGQTSVAVMPLAGSQSV--VVNNHAQRAGSLITLFIMVTAYDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMTRRLMDTA-ALKAGHDNDTSVRDVATVLKRLANQRLISSKVDH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVRNRQGT-FIMTMMAAS +GER--TAQTSAMNDLGQVLYR-- +>[subseq from] Uncharacterized protein n=2 Tax=Actinobacteria TaxID=1760 RepID=D9UYN6_9ACTN +---ASETIARRAEEVGVEVRLHAAEVDGNRSL-GIGEDVPVVPASVFKVPIALELARQAA +DGTLDLGARIAVKPGHPTPPYGLATFRHEVLMSWHDLAILMIGISDNVATDLILAEI-GK +DAVNSTLRRLGFTHTVVPQDCAELLAALQPEKSCRTTAAEMTRLLGLIWRDEAAAPEACA +DVRRWMELQVW-PHRLRSGFPDGIRTSGKTGTLP-AVRNEVGVVEYPDGGRYSVAVFTRA +EDSRVPERDAFIGFAAATAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. Ag82_O1-9 TaxID=1938856 RepID=A0A3D9W3G7_9ACTN +----EDRLAQVFAEAGCQGSVAVLDIDGPGQV-VLGGDELVVAASTFKIAAALELFCRGA +EGELDLAERVRLAPSQATPGQGFCIFEDEAEVSLRDLARMMVTISDNTATDVLIRRV-SV +PRIHARLAALGLDRIRLAGTIQEEFDSLRPGRITSATAGQMAALLRMIWRDEAGPAEACA +AVRSVLGQQRL-TRKIAAGFGDEVRVAAKSGTVPGCVSNDAGVVHFPDGSRFAVAVFTRP +TGPRPPQSDSVMGTVARLGVE-- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. EGI 650086 TaxID=1840409 RepID=UPI00131E55DE +---------------------HARCVGCDHGA-GLRADEPVVLSSVVKVPLVLEFARQVA +AGQLDPADRVRVRAADRLGGTGTAGCADDVEFSLRDAALFALSLSDNTAADLLFDRV-GL +ANVRSLVRELGLANTRIYGSPRDILRALDPRHATASTPRELTRLLQLVWRDEAGPAEACA +QVRALMRQQIN-WYRLTAGFPPEVRVAGKTGTLP-GMRAEIGVAEYPDGGRYAVAVFTRA +DTQRLPHVDRAIGEAALAAV--- +>[subseq from] Serine hydrolase n=1 Tax=Cyanobium sp. NAT70 TaxID=2024872 RepID=A0A2E0AK44_9CYAN +-kALSEKWKQLASQHDLQASGYMLVLDDGRFA-QMNAEQPMPAASSIKTPILLAALELVD +SGDLQWNEPLTLTKELVGGGAGWMASPLGSRFPTFEVATEMIRVSDNSATNLLIQRVGGK +TAINDRFKVLDLPATEVNNWLPDLDGT------NTTSAKDLSRSIALVDSGDQLGPRSRD +LFREVMSTSVT-NTLLPTGLLRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG +PFND-PRSTNLIRAMASAM---- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Candidatus Woesebacteria bacterium CG07_land_8_20_14_0_80_44_9 TaxID=1975058 RepID=A0A2M6YFC9_9BACT +---VLTEIENLTKGLRGTYGVYVYQLDGKNEY-GIHQGEIFPAASLMKLPVMLTLYQEAQ +AGQASLETKYKLTEKDKINGAGILQKPVGSTYTYRQLAEFMGQYSDNTANNILVKVL-GQ +EKIQQTISKLGMTKTSFKNY--------------TTTPEDIGIFFRQLYQGGIVNKENQD +EILRFLTKTAF-EDWIPAGLANDIRVAHKIGKDI-GAFSDAGIVF--GRQPFVLVIMSKD +AKES--EVKETLPKITKAVWE-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000FF8EFA1 +----THLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000A17A013 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A165RBK9_LACPN +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A3E2V4D6_9FIRM +--TLEKRIAAELYSYQGKMSVFVDDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAS +RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA +AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE +FHD-------------------- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007C84ADB +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A0G9GVX1_LACPN +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] hypothetical protein n=1 Tax=Facklamia sourekii TaxID=87650 RepID=UPI0012ED9C0D +------CFEEAFHSLSGDHSLYYQDLTQADATkLVINSNPMRSASLIKLFILAVFFQQVA +DDQIRLNQTYILQDADKVGGTGTLQQQAEGSYSFLDLAQEMIINSDNTATNILIKQLGGL +SSVQEQINQWDYGDTQLNRYMLDFDA-LASGQDNYTSVEDIANLLRSCYRQELISPVLDR +QMLTILSQQKD-RSKLLARLGHKVKIYGKSGQFQYGVLGDAVIVKQGAK-AYLLIILSQD +GEEQ--DQYPAFNKVGLTVY--- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000CE94A8F +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Butyricicoccus sp. 1XD8-22 TaxID=2320083 RepID=A0A658JGY0_9CLOT +----KEELERLIDSVDYNIHLFIKEAKAEDFIfAKKLDEVVSSASLIKVPILIAVLELIE +RQNISLQMEVEIKQNHKVEYSVLTEQDSD-KSKLYELLVWMIITSDNTATNVLIDFL-GM +EECNAFFKKIGLTRTKLQRKMMDFDS-LQKGVDNVTTARDMANLFTRIYKQDLLPLQFSQ +LAIDILSRQRI-NDGLKRYIIENVKIAHK------------------------------- +----------------------- +>[subseq from] Putative beta-lactamase related protein n=1 Tax=Streptomyces sp. Tu6071 TaxID=355249 RepID=F3ZHT7_9ACTN +--------------------VHAVDIDRGTET-GWEADRLVCTASVHKLCLLLALHRLAA +AGRIDLTERVECPVEGRTPGTGLAAMLDAPRMSLRDLAYLMIAVSDNAAADLLLARI-GL +EEVNRTTEALGLRRTRAVESFAATQEALDPAHGNRSTPRELTRLLAALWRDEFLPEPHGA +AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA +ADHVVPAADAVIGVVGRIVVD-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000FF49C4D +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Serine hydrolase n=1 Tax=Microbacterium oxydans TaxID=82380 RepID=A0A4Y4GBH5_9MICO +---VERRIAEIFADAGATGFLHAREIGGGPEV-TVGADEPVVLASVFKILVLTAFVRAVA +AGELDPAARTTVTARYRIGGVGTAGFADDVEMSWRDLALNMMTMSDNAATDVIYHRL-GA +EAINRVISDLALRQTQLVGCCEDLFAAVQPLRTSHSTPREVTAVLNALWTDAAAAPEACR +QARDIMALQIW-PHRLTSGFPAEVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA +ASLS-DRQPLVDASIGRAAF--- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A165NPA4_LACPN +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000350773E +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000BE3B228 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000B3E499D +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora echinospora TaxID=1877 RepID=A0A1C4ZAH6_MICEC +------------ARVGVDARLHAVDVDTGHEV-GVDADEQVVIASVFKILLVLEFARQAA +NGQLDPTERVVVRAGDRLGGWGTAGCADDVELSLRDLAYFAMSVSDNTAADLLMRRV-GP +DLLPLLAAELGLTRTRVIGGPRQLLEVFDPEQTTSSTAREITRLLTMIWRDEAGPPAACA +MVRDLMSRQLF-WTRLPSGFPPDVPVAAKTGTLP-GLHIEAGVAQYPDGGRYAIAVFART +QRTRRIDVDLAMGEAARAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Jiangella sp. DSM 45060 TaxID=1798224 RepID=UPI000B84FC48 +------------------GFLHAADVGSGAEV-GVEPDAPVVTASVFKIPVLVELCRQFA +TGERAPADRLRVPAGGRTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR +EKINAGMAALGLTGTVLEEDCAGLFRVLDARTTNRSTPRETTTLLRRVWTADGLPEAACD +EIRRILALQVW-PHRLTSGFPDDVRVSGKTGTLSH-VRNEVGVVEYPDGGTYAVAVFLRL +PGPENPAADAVIGTAARIAVDH- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0001B00022 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLSLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora inyonensis TaxID=47866 RepID=A0A1C6SFK3_9ACTN +--------------VGVDARLHAVDIDTGHEI-GVGADEQVVIASVFKILLVLEFARQAA +DGQLDPTERVVVRAEDRLGGWGTAGCADDVELSLRDLAYFTMSVSDNTAADLLMRRV-GP +DLLPLLAAELGLPRTRVIGGPRQLLEVFDPDKTTSSTAREITRLLTLVWRDEAGPPAACA +MVRDLMSRQLF-WTRLPSGFPPDVPVAAKTGTLP-GLHMEAGVVRYPDGGRYAVAVFAQT +RRLTRIDVDLAMGEAARMAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=bacterium (Candidatus Howlettbacteria) CG_4_10_14_0_8_um_filter_40_9 TaxID=2014279 RepID=A0A2M7RM54_9BACT +--ELLGEINEYLETTPGTYGLYVHELGTDKSF-GINEEMSFPAASTVKIPLLMSLYKDIY +EGKVSKDTVMTYTINDEETGTGIQYTSFGTRWTVSEIAKRMMKQSDNVAKNMIFRLV-GY +RRAQEYITGLGVKGVDMS-------------LENKTTSKDSGTLLKLIYENKTVDKELSD +EMLELMVKTDF-EKRLPRYLE-GVKVSHKIGTWA-GAISDTGIVFLEGR-PYTISVYSEG +IQ-SVDEAEKVIGTISKKVYDY- +>[subseq from] serine hydrolase n=1 Tax=Megasphaera stantonii TaxID=2144175 RepID=UPI001300A395 +-------------QDKAAVSVYCRPLDGGDDF--FYRDRVMPSASLIKVPIMACVFRQEK +EGQLSFDTTYPVYG--GVEGGSFYGLPEGTEVSLRTLVFHMIVESDNTCTNMLIDVL-GF +DAINEEIRRQGMEHTLLRRKMMDFEAA-RQGKENVTSPGDMGRLFLRLASGTCVDGRRDE +AMRAILAQQED-NCILPAQIPHTVTVEHKTGELD-GIYHDCGLVWKQGR-PYVCCLMADG +IV--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Nitrospinae bacterium TaxID=2026769 RepID=A0A3M1RL20_9BACT +-eALVQQLHRLCDSYPFHTGWYLKDLRTGEVA-QRNGDVIVPSASTRKIAIMMAALKAVN +EGKLSLNQPVTIQARYQNNQSGTFQHQPGFTIQFRDALVMMIIVSDNTCTGTIVDML-GL +DYINAFCQSIGMRGTTHRHGIPRLGRHHPVEAVNATTPADVGLLLDLILQGTGCTPALCQ +LGLDILSWQKL-SWRLPAYLPWGTKVAHKTGTGQDGNNNDAGIIFQGEEPLFILSVFTEQ +VPQEMPDG--------------- +>[subseq from] Uncharacterized protein n=1 Tax=Novibacillus thermophilus TaxID=1471761 RepID=A0A1U9K726_9BACL +--ALKENVEQIANSLTGEIAVFIET--SEGTI-AMNETDVMSAASTIKVPILVEAIKQAE +QGDLFWDDEVVVEESDAVGGSGVIKDELPQTFTVRELAELMITVSDNTATNMIMERV-GF +DEVNWACIEMGCVDTVLQTSIYTSMPQ-DRGPHNYSNVKDMVTILKGANEGGFLSPEGRE +EFLSIMRDANQ--ARLSEYQDKDILVGRKGGSTAPRVLHDVGIFTLGDE-HVYAAVFTKD +VQPS--IATPTIGEIGRSIMDY- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus plantarum subsp. plantarum TaxID=337330 RepID=A0A2S3U749_LACPN +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRSADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Predicted protein n=2 Tax=Actinobacteria TaxID=1760 RepID=D9UYN4_9ACTN +----RERIEAVFADAGAEGFLHAREIGPGPDV-SAGGDDPVVLASVFKIPVALAYAREVT +AGRLDDTERTKVTARYRTGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRL-GQ +ETVDRVLADLGLARTRLIGCCEDLFAVRDPERTTSSTPREITELLDAIWTDRAGEPEACQ +RVRTIMAQQIW-PHRLSSGFPSGVRVAAKTGTLP-GIRNEAGVVTLGDGRQFAVAVFTRA +HSDRLPAVDASIGAAARLAIDH- +>[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces sp. 840.1 TaxID=2485152 RepID=A0A3N1S205_9ACTN +----ERAIRDMFDDAGVRGWLHVADLRRPAARvVIDPGEELPLGSVYKLPLMAAFCRLAD +AGRLDPCHRVTLDAADRVPPTGVSILQDPVTMSLRDLVTLMMTVSDNTAAAAVLRAV-GA +DAVDAVCRLLGMPDTHVRGGVVSTFSVYDPAFKASGTPADLARLLRAVWTDEAASAEGCA +FMREVMRRQPW-THRLASGFPDDVTVYGKTGTFGS-LRHEAGVVELADGSIYTAVVFTQA +ARADLPRADAVIGAAARAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI00092FE446 +---VTDLIEQATNGLAGQTSVAVMPLAGSQSV--VVNNHAQRAGSLITLFIMVTAYDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYSEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMTRRLMDTA-ALKAGHDNDTSVRDVATVLKRLANQRLISSKVDH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVRNRQGT-FIMTMMAAS +GER--TAQTSAMNDLGQVLYR-- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium neonatale TaxID=137838 RepID=A0A2A7MEL5_9CLOT +--SLEARIEAELISYAGKMCVYVNDF-KGNTI-EIGADEKFETASCIKSFILADLFSQVE +NGTKDLYEKLKYTKKNYINGSGVIQSLDEGVMTAINFAKLMIIVSDNVATNILIDYL-GI +DHINKTIQELGFKDTILHNKI-DFEK---YDKLGTTTPRDYGRLFELIAKKELISEEASN +KMLDIFKMQHY-NSMIVRDFPQYIYVASKSGSMD-ACRNDGGLVFTPYG-PYVIVMFNKE +FHDSNHDATVYGGKVSRMIFDEf +>[subseq from] Uncharacterized protein n=1 Tax=Gordonia namibiensis NBRC 108229 TaxID=1208314 RepID=K6X9E3_9ACTN +--RVDRDVAEILADAGCSGWVHATTIGSPQIEhSFDADAPVVLASVYKLAVLISLCRSAD +RGDIDLASSITVDPTLWAQGPTGLAAFGDPVLSRRDLAISMMTVSDNVAADVLLDEL-GL +DRVRADLVSLGAERTRIVGGVAELHEAYDAAYSSSSTPRDCTALLSAVWTDRAASPEMCA +FIRDTMRRQVF-TARLASGFPRRVTVAGKTGTLV-AIRNEIGVVEFPGELPVAVAVFTAR +SEQSLPQVDRAIGEAARTVVT-- +>[subseq from] serine hydrolase n=1 Tax=Muricauda sp. MT-229 TaxID=2597517 RepID=UPI00118F7A61 +---LESRVKGALESFTGKASSVIE--TNNYRI-DFKGHEQLKSASTIKLAVLLEAYRQID +RNLLKPYSIIKMKPEDFTEGSGVLFHLNSVNLSFEDLLTLMIIVSDNTASNIAIRTV-GM +DRVNKLLHDLDCSQTLLGREFMDFGAA-RQGLDNFTSAADLVTMLKAADSDGLLSEDSRR +RVFHILKKQQI-LANLHGRIDEEVSIASKSGNLP-GVVNDAGVFEYRGNK-VYAAVVIND +SP-DNHSGQELIAEIGSYIYD-- +>[subseq from] serine hydrolase n=1 Tax=Desulfofundulus sp. TPOSR TaxID=2714340 RepID=UPI0014085ECD +---LQKQLKDYLAQQPGVYGIYFKDLHSGASF-DINGDEPITAASTVKVPVVLYLNHLVA +QGKLDWDDRVVYDSKDYQGGAGILQFSARDGYSLRVLANLSITISDNIAYRMLVRHL-GK +DNVAQFMRDLGGQTV------------FPG-GENITTARDMGRYMEAVLEFSREHPALGE +RLLDDMANPIY-HVGLPGRLPPEVRVAHKEGDVW-GVANDAGIVFAE--HPYILVVLSKG +ET-DVDKGFARIAEISRMVYDY- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia seriolae TaxID=37332 RepID=A0A0B8NGD4_9NOCA +----------IFRTAGVEGRVHARCFDCDGEF-GWGADEPVVLSSVVKVPLVLEFARQVA +AGQLDATDRVRATAADRLGGVGTAGCLDDVEYSLRDAAYFALTVSDNTAADLLFDRV-GV +DNVRSLVRELGLTRTRVDGSLRDILYAVDPLRTTASTPRDMTRMLLLIGQDLAGVPEACG +WVRDLMRRQVF-GHRLPSGFAPGTDVWSKTGTLP-GIRNEIGVVGYPDGSRYAIAVFTVS +HSGRQPAVDRAIGEAARQAVE-- +>[subseq from] Peptidoglycan-binding protein n=1 Tax=Caldanaerobacter subterraneus subsp. yonseiensis KB-1 TaxID=1388761 RepID=U5CV96_CALSX +-qELKQNIEKLISQYPGKYGVYFIDLNTGQTF-EINGYDPFIAASTYKVPLNFYLYTLIT +EGKIDPNMKVQYTKVDYEGGAGSIQFEPVGSYTIRELSRRSIVESDNIASNMIMRVV-GR +DNYIKFMENLGAKVIPYS--------------SNIASPYDMSMYMKKLLEYENEHPDTAG +ELMYYLKNTIY-GDRISYPIPDNIEVAHKVGNLDN-VVNDTAIVFHPTK-PYILTILANN +VDSDNSYAYTVIRQISKMVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Vagococcus fessus TaxID=120370 RepID=A0A430A8U8_9ENTE +--ELPDKIVEKVKGLKGYYSYYLHDLSEPSGV--SGSSKKMLSASTIKLFILEKAFAQVK +ADKLELDEPYELLEEDKVPGTGIQNAKEGTTYTTEDLLNLMIVDSDNTATNIIIDRLGGI +EELSDYILDRGYGETTLARKMGDTA-AISEGKDNYTSVDDVGRLMSKLAKKELIGKAEDE +KMLEILSNGKN-HDKLAKHLPDNLTIYCKSGEYDFGVQNDTILVEGPEGD-YILTIMSEG +GDES--EQVSVMQTIGQEAYQ-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000DED33BD +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPSGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Uncharacterized protein n=1 Tax=Achromobacter sp. TaxID=134375 RepID=A0A0M7HIH1_9BURK +-qHVDAALAPLLAATPARVSLSLRDLDGGVVL-ARQADRAQPSASIIKIPILLALLEAVA +GGRYTLGQPLVLPAADRAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIELL-GF +DEINQWSQRAGLPASRLQRRMMDAAA-REAGRDNFTSADDATAALCWLLRDGMLPAPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A5F0YB59_LACPN +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMVRRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0006D49AC2 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMVRRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Williamsia limnetica TaxID=882452 RepID=A0A318RQT6_9NOCA +----GQRLREIFADAGCAAWLHARTIGPEREF-DWYADDPVVMASVYKLPLFAALCVRAD +NGDIDLREKVTVDPREQAAPTGIAALHDPITLSWRDLAVQMMVVSDNAAADVILAEV-GL +DYVHKVLDEAGLHATHVVGGMAHVQKAYDPALAGATTARDATSLLDLIWTDRVASRHSCD +FIRTTMRKQAW-KQRISSGFPLGATVAGKTGTLG-AIRNEVAVVEYPGEYPVAVAVFTHA +ARLSLPTVEAAIGQAARVAVN-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3L7YJ02_9CHLR +--DLNSALEAAISGIQGDFAWHIEDPSMGRAW-TRNAHEAYPAASTLKVAVFLRLLQLVD +DGRVGLDHQIRLRRWHQVGGAGVLQYFSPETLTVGEVATLMVILSDNTATNMIIDLT-GL +GAVNNLVASLASRVTRINRYYGKPSMALPDGTHAMATANDLATIYREVLAGKILGPIGRQ +AFWQTLLRQQD-RAMAPRHFGPDILIAHKTGAID-GVRNDVGVFWLPES----------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 2131.1 TaxID=1855346 RepID=A0A1H5IQI6_9ACTN +-----TALRTAFTDAGVTGRIHALDIGSGAEL-DLYGDELVCTASIHKLPLLVTLHERAA +AGDLDLTEQIDCPPLGRPAGPTGLAAMLDVALSLRDLAYLMMAVSDNAAADLLLDRV-GL +DAVNRTAARLGLSRTTVTHSFGEMMAALDPAWGNRSTPRELTRLLAAIWRDEVCTPENGD +AMRRLMALQVW-PHRLASGFPDDVHVAGKTGSLPT-LRGEVGVVEYPDGGQYAVAVFTRT +LSAIVPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=2 Tax=Bryocella elongata TaxID=863522 RepID=A0A1H5SZV6_9BACT +---VQAEVEALAASHQGKVGVYLHQLNTDKTV-ALNADEPVQTASVIKLGLLYEAMVEVR +EGKARWDEKITVPANYTVGGSGFLQFFDTPMLTLKDVLSLMVIVSDNSATDLAIDRI-GV +DAVNQRMGQLGLKNTWLYKRIGTMPADQPKFGLGKTTPREMAILMETIG----------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Williamsia sp. D3 TaxID=1313067 RepID=V8D0D7_9NOCA +---------------------------VEREF-DWAADDPVVMASVYKLPLLLALCDLAE +IGQIDLTATVVVDPADWAVPTGIATLHDPVTLSWRDLAVQMMVISDNAAADVILDRV-GL +PRVQEKLDALGLTETRVVGGMAELQQAYDPALASATTPRDGTRLLQLIWTDRAVSAQMSE +FVRSTMRKQAW-QQRLSSGFPLGVTIAGKTGTLG-AIRNEIAVVEYPGEHPIAVAVFTLA +ARLSLPTVEAAVGRAARIAV--- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007B5518E +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALY--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL F-3213 TaxID=1463846 RepID=UPI00055E0EB1 +----RERIEAVFADAGAEGFLHAREIGPGPEV-SAGGDDPVVLASVFKIPVALAYAREVA +AGRLDDTERTKVTARYRIGGIGTAGCADDVEMSWRDVAHFMLTMSDNAATDVLYHRL-GQ +ETVDRVLSDLGLERTRLIGCCEDLFAVRDPERTTSSTPREITELLDAIWTERAGEPEACE +RVRTIMAQQIW-PHRLSSGFPSGVAIAAKTGTLP-GIRNEAGVVTLGDGRRFAVAVFTRA +HSDRVPAVDASIGAAARLAVDH- +>[subseq from] Beta-lactamase n=1 Tax=Microgenomates group bacterium Gr01-1014_7 TaxID=2017209 RepID=A0A554L178_9BACT +--NLKQVVDNELRGEKGKYGIYIENLKTGETF-AKNEHESFEAGSLYKLWLLGAVFEKIK +DGTLKEDEILSGDIADLNTKFDIASDELTEGLTVKDAIEQMITISHNYSALLLTSKM-GS +SKINDFILKYGFNESSPGPP-------------VKTTASDMARFFEELYAGRIIDKESSE +KMLEILSRQQV-RDRITKNLPGGVRVAHKTADIGF-FEHDVGIVFTPKGD-YVIVVLTET +DSP--EKTAQKIAEISKAVYEYf +>[subseq from] Beta-lactamase n=2 Tax=Prochlorococcus marinus TaxID=1219 RepID=A0A163QTV0_PROMR +---LSNRWRDLAKQQDLQASAFLLVLDDGRYA-ELSAETALPAASSIKTAILLVALELID +SGQLSWNEPLKLTKEIIGGGAGWMAKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGK +NVLNARFNALGLSSTVVNNWLPDLQGT------NTTSSHDLARAIALVDTGKALSPRTRD +LFREAMSTSVS-NRLLPGGFLKGYRIYNKTGDIGI-AYSDAGLIELPDGSRAVAGFMVKG +PFND-PRSTELIRDMAAAM---- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces kasugaensis TaxID=1946 RepID=A0A4Q9I040_STRKA +--TAEARIQEAFDAAGVRGYFFAREIDGDRTL-GVAADEPVCLASVFKIPVALAYAREAA +AGRLVRTERLAVDPHYRDGGIGTAGCADPVEMSLRDLVHMMLTMSDNAATDVVLERV-GL +DTVNGLLRELGRDRTHLVGGCLELTGVCVPERTTRGTARDIAELLAQIWRDEAGPAEACA +EVREVMSHQIW-PHRIGAGFDDGYRLAGKTGTLP-GWRNEAGVVEHTDGGRWAVSVFTWS +RTPDNPAADRVIGTVARLAVDE- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000CDE0C1E +----TDLVAQSTNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis circi TaxID=871959 RepID=UPI000E25BDD3 +----REQIEAVFADAGAEGFLHAREIGQGPEV-SAGGDDPVVLASVFKIPVALAYAREVA +AGRLDDTERTKVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVLYHRL-GQ +ETVDRVLADLGLARTRLIGCCEDLFAVRDPERTTSSTPREITTLLDAIWTDRAGEPEACE +RVRTIMAQQIW-PHRLSSGFPSGVAIAAKTGTLP-GIRNEAGAVTLGDGRRFAVAVFTRA +HSDRLPAVDASIGAAARLALDH- +>[subseq from] serine hydrolase n=1 Tax=Nocardia vinacea TaxID=96468 RepID=UPI0002EFAE07 +--------EEIFRKAGVRGWVHARCLDCAGEV-GLGADEPVVLASVVKVPLVLEFARQVV +AGQLDPTDRVRASAADRLGGVGTAGCLDDVEFSLRDAAFFALTVSDNTAADLLFDRV-GL +DNVRSLVRELGLTETRIVGSPRYVVQAMDPLRTTASTPRDMTRLLTLLGQDRAGDPAACR +WVRELMGQQLN-WHRLAAAFPSEVSVWGKTGSLP-AIRNEIGVVAYPGGSRYAVAVFTRA +DTQRLPEVEHAIGEAARLAIH-- +>[subseq from] serine hydrolase n=1 Tax=Williamsia sp. D3 TaxID=1313067 RepID=UPI00068592F8 +---------------------------VEREF-DWAADDPVVMASVYKLPLLLALCDLAE +IGQIDLTATVVVDPADWAVPTGIATLHDPVTLSWRDLAVQMMVISDNAAADVILDRV-GL +PRVQEKLDALGLTETRVVGGMAELQQAYDPALASATTPRDGTRLLQLIWTDRAVSAQMSE +FVRSTMRKQAW-QQRLSSGFPLGVTIAGKTGTLG-AIRNEIAVVEYPGEHPIAVAVFTLA +ARLSLPTVEAAVGRAARIAV--- +>[subseq from] serine hydrolase n=1 Tax=Mycolicibacterium canariasense TaxID=228230 RepID=UPI000A158400 +------------------------------------------------------------ +-----------------------------------------------------------P +SAITEFARSIGDNETRLDRWETELNSATPGDARDTSTPQALGDGNRALLEGTALTLESRR +QLIEWMVANST--SSLRPGMPPEWILADKTGSGGYGSTNDVGLGFGPGGQQVVLSVMMRS +ATPNADGFRPVMTEIAAVAM--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI00101E787B +----------------------------DGEI-AIGADEPVVIASIFKVLLVLEFARQVA +AGQLDPRERVRVTRGDRLGGWGTAGCADDIELSLRDLAFFAMTVSDNSAADLLLARI-GL +DTVRLLAGELGLDRTRIVGGPRDVLEALDPLRTNASTPREITRLLRLVWQDEAGPPQACT +QVRELMARQAF-RHRLVSGFPDGVAVAAKTGTLP-GLHMEAGVIRYPDGGLYAVAVFARS +REASRTEVDAAIGATARVAVD-- +>[subseq from] Uncharacterized protein n=3 Tax=Gordonia TaxID=2053 RepID=F9VW03_9ACTN +--RIDRNVAEILADAGCSGWLHATTIGSPQISySYDADAPVVLASVYKLAVLISLCRSAD +RGEIDLTSPVTVDPTRWAQPTGLATLRDPITLSRRDLATSMMTVSDNVAADVLLDEI-GL +DRVREDLIGLGATSTRIVGGVAELHEAYDAAYTSSSTPRDCSTVLTAVWTDRAASAEMCA +FIRDTMRRQVF-TSRLASGFPRRVTVAGKTGTLV-AIRNEVGVVEFPGELPVAVAVFTRS +ARPALPQVDRAIGELARTVVT-- +>[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814) TaxID=580327 RepID=D9TSS5_THETC +-qELKNNIETLLSQHPGKYGVYFIDLNSGETF-DINGYDSFVAASTYKVPLNFYLYTLIT +EGKIDPNMEVQYTSQDYESGSGSIQYDPVGTYTIRELSRRSIEESDNIASNMIMRVV-GY +DNYLNFMKSMGANVIPY--------------TSNITSPRDLSLYMENLLNYVNAHSGTAG +ELLNYLENTIY-NDRISYPLPSNITVAHKIGNLSD-VVNDTAIVFYPSK-PYILTVMGNN +VDSDNSDAYTVIREISKMVYD-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Candidatus Shapirobacteria bacterium CG10_big_fil_rev_8_21_14_0_10_40_9 TaxID=1974888 RepID=A0A2M8L3C2_9BACT +-----TEIENLTKGLRGNYGVXXXQLDGKNEY-GIHQVEIFPATSLMKLPVMLTLYQEAQ +AGQTSLETKYKLTEKDKIIGAGILQSKPTGSYTYRQLAEFMGQYSDNTANNVLVKVL-GP +EKIQQTISNLGMTKTSFKNY--------------TTTPEDIGIFFRQLYQGGVVNNQHRD +EILRFLTKTAF-EEWIPAGVPKDIRVAHKIGKDI-GTFSDGGIIFAE--KPFVLVIMSKD +AKES--EAKEVLAKITQVV---- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. 14-2483-1-1 TaxID=2023148 RepID=UPI000B9A4FB2 +--TTDEQLRAVFADAGCRGWVRAERIDGTGTVvDYEGDEPVVAASVWKIVLLVAAARAFD +EGSLTATDSVRLVPAQCSPPTGISSYADPVTMSWRDIARSMITVSDNAAADALLGAL-GL +DSLATVIEDLGLEQTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSIWLGTAASQAQCR +YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGEKPVAVSVFTRA +ARMDLPLVDQAIGSAARIAV--- +>[subseq from] serine hydrolase n=1 Tax=Clostridium amazonitimonense TaxID=1499689 RepID=UPI00050995D2 +------EIKKYLESRIGQHSFYFEDLEGGYVY-GYNENVQMISAGCMKLPIAIAILKEAE +NGKFDLKDKVTVFREDKVSGTGIIHEFGEREYNLSELLIAMLIQSDNTAANKLIDMI-GM +PRINELFQEMSLKNTVINRKILEEK-DVKNVVQNITSSYDLCLCWKHLYKHSYLNEEHSK +MVIDILKRQQM-KNKVAFYIPEDIKMANKTGDLS-GVENDTALIQISKGN-FAFTVMSQG +IPN-NVYGNITLAKCGKMMWD-- +>[subseq from] Beta-lactamase n=2 Tax=Prochlorococcus marinus TaxID=1219 RepID=A0A163WTM1_PROMR +--TLSNRWRELAKQQDLQASAFLLVLDDGRYA-ELSPETALPAASSIKTAILLVALELID +SGQLSWNEPLKLTKEIIGGGAGWMAKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGK +DVLNARFNALGLSSTVVNNWLPDLQGT------NTTSSHDLARAIALVDTGKALSPRTRD +LFREAMSTSVS-NRLLPGGFLKGYRIYNKTGDIGI-AYADAGLIELPDGSRAVAGFMVKG +PFND-PRSTELIRDMAAAM---- +>[subseq from] serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=UPI0013014C05 +--------------------------QTHETL-TRDPDQVMETASVIKLPIMAATFQYLA +DEHKTLSEPLTLQVEDMVDGSGILQHLSPGLLSIKDVMTLMIIVSDNTATNMILRQF-GI +PRVNRFIQSLGLSQTRLLKRIDF---TIPG-PIGLATARELGMILTQLYHRTLVNKDASD +VMWDILCRQQY-NTIMTRHLPPKVQIGSKSGSLE-GIRNDVGIITTPWGD-YVLAILSEH +SRHIDNEALVILPQLSRIIFDYf +>[subseq from] Uncharacterized protein n=1 Tax=bacterium SCGC AG-212-C10 TaxID=1799370 RepID=A0A177PVW2_9BACT +--RLHSAILDAVAGAGGSTSVVVLRLGDGLAA-EVDGDGQYYAASLFKLAILYEAERRIS +LGEFSLDSPVLYTAEAFAETVGSLS-FSDDGIPLGDALAAMVEISDNSSAIAIVRML-GP +GTVDETMRSLGLEVTSVNTTELP------------TTARDMARLMQAIVNGEGVTETQRQ +HMRQLLLGQHT-RDGIPAGLPEGIVSGNKTGTWD-GATHDVAFVDAPGGE-YVIAVLTDR +GW-----DWPTIANVSAAVY--- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora palomenae TaxID=1461247 RepID=A0A561WCB5_9ACTN +---AEQRVEEIFARAGGSLHVVGVDGPAGREV-AVRADEQTPIASVFKILLVLEFARQVA +AGQLDASERVLVRADDRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GA +DVLPMLAAELDLPRTRILGGPRQLVEVFDPAHTTSSTPREITRLLGLIWRDEAGPAPACA +TVRELMSRQLF-WTRLASGFPAGVRVAAKTGTLP-GLHLEAGVAEYPDGSRYALAVFART +DRTRRIDVDLAMGEAARTAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8JJU3_9BACT +---------------SGRLGVSALLFDRRAHI-GFNEDDRFPMASVVKVPIGMLIACEIA +NRTLSVDEKIRIHSRTASPGNPLDRFYFPFEHTVDQLMAFMLHHSDNTATDAILHRLGGI +GALTNFLRDLQIEGISIKRTMHELLTHLIRTGEETCTPRAMAQLLKLLTLNS-----KYA +LVYSHMQRCATNKRRIAEGLKEQKSFGHKTGSLG-AIANDVGILHLKNGYFAALAVMTCH +SAVRMPVRDNEIATVTRAVIGQw +>[subseq from] Serine hydrolase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A6B1N5G7_9ACTN +------VLSDIFEHAEAEGFVHARDLDSGAEF-GYRADDRVVLASVFKIPIALEYARQAA +ASDLDPAARHTVTAAYRSGGSATDGCAYDVEMSARDLAFMMMTISDNAATDLLLDIV-GI +ERVRALLDGLGFPGFGVSS-CRALDDVNDPARSPSSTPREVTALLAAIWRDEAGPGRACA +EARDIMGQQVW-QHRLVSGFPSRVRLAGKTGTDF-AIRNEAGVVQYPDGKRYAVGVFLRT +SRDRQPRADRAIGLAARAVIDH- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 04197 TaxID=2203199 RepID=A0A429DXV4_9PSEU +--DIRERIEAVFAAAGAEGSLHAREIGDGAEV-SVGADDQVVLASVFKIPIALAYAREVV +AGRLDETEYTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWNRI-GQ +ETICRVVADLGLTRTRLIGSCEDSFRMCDPERETSSTPRETTELLDAIWTDRAGEPEACE +RVRTIMAQQIW-PHRLSAGFPSDVRIAAKTGTLP-GIRNEAGVVTLPEGRRFAVAVFTRA +HSGRLPEVDASIGAAARLALDH- +>[subseq from] Beta-lactamase n=1 Tax=Crocosphaera watsonii WH 0401 TaxID=555881 RepID=T2J8W3_CROWT +------------------------------------------------------------ +-----------------------------NKFTALEVARKMIVISDNTATEMLVKQMGGK +EVLNKRFKEWGMKNTEINNILPDLEGT------NKTSSEDLSKLLARIERGDLISARSRD +RLIDIMEGTRT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER +AYND-VAGRHLIQDISRTVYQHf +>[subseq from] Secreted beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=D5ZPI6_STRV1 +-----------------------------REV-AVGADDPVVIASIFKVLLVLEFARQVV +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNTAADLLLARV-GP +DTVRLLARELGLERTRIVGGPRDLLEVLDPRHTTASTPREITRLLRLVWSDAAGPPEACA +FVRDLMSRQVF-RHRLASGFPDDVAVAAKTGTLP-GLHMEAGVARYPDGACYAIAVFART +RDVSRATVDAAIGRAAGI----- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=A0A2A2ULN5_9ACTN +----------------------------DGEI-AIGADEPVVIASIFKVLLVLEFARQVA +AGQLDPRERVRVTRGDRLGGWGTAGCADDIELSLRDLAFFAMTVSDNSAADLLLARI-GL +DTVRLLAGELGLDRTRIVGGPRDVLEALDPLRTNASTPREITRLLRLVWQDEAGPPQACS +QVRELMARQAF-RHRLVSGFPDGVAVAAKTGTLP-GLHMEAGVIRYPDGGLYAVAVFARS +REASRTEVDAAIGATARVAVD-- +>[subseq from] Beta-lactamase class A n=2 Tax=Gluconacetobacter liquefaciens TaxID=89584 RepID=A0A370GB20_GLULI +--AMADAVARLTAGQPGEFAVYAAPSGQAPDV-CLHCDEPINAASTIKLLVLDAAYAAFR +DGTLKPDEAIIVHNRSLVGGSFSLYAEAGRPVTVIELLRVMIQYSSNLATNLMVERL-GV +IQIRGVVAQQGLEGITFGRMIEDFDAD-AKGIRNRVTARGLGGFLQKLDHGAIVGPAESR +AMIGIMLGQTF-NDLIPPGLPGGTLVAHKTGWVN-GVRNDAAIVFLPNGAHYILVELSRD +LP-DEAAGIKVLNAISSTVFKAy +>[subseq from] serine hydrolase n=1 Tax=Clostridiaceae bacterium TaxID=1898204 RepID=UPI0011DE4DF4 +-----KEIKKYLESRIGKYSFFFEDLKSGYVY-GYNENVSMTAAGCMKLPIAVSLIKAVE +DKKVDFMDKIKIQTSDKVYGTGIIHEFNEREYTVFELMVIMLIQSDNTAANKIIDIV-GM +EQINEDIIAMGLKNTRLNRKTNDERTD-ITDIENITTAYDLSKIWKHLSNGTFLSKDNGQ +MLIDILRRQQI-KNKLALYIPDDIEISSKTGDKK-GVENDTAYLELPKGK-FVFTVLSQD +IPNS-VYGTVSLAKCGKMMW--- +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora dendranthemae TaxID=1181886 RepID=A0A561UA24_9PSEU +-------------ELPGRVGIASWDLRENAPV-LRGAEVEVHSASTIKVLVMITALRAVA +DGRSNLDELVPLPPER-TRGTGVLFEMPSVPISLRDLINLMIVVSDNAATNAVIDQV-GF +RAIAECTSDLGCTGTRIERHIMDTEA--PGVLR--TTALDQARVLAALAEGEALPPELAE +HALAVLSRQQV-VDRIPLLLPENARCWNKTGEIK-GLRHDVALLSTDDTPQVVLAVLVDQ +LTDP------------------- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus circulans TaxID=1397 RepID=A0A3G4ZD51_BACCI +-eKLSKRIDKIVQEYEGHLGIAIEW--KEQSF-LLNENDIFPSASLIKLPVLIEGFMQSS +SGILDLEDLVKVNSLQKTGGAGIVQYMSPQSLSIRDLLTLMIIVSDNMATNYLIERL-GM +DNVNKRCQQIGMSSTILQRKMMDRE-ARERKIENYTSPQDILRCLKSIYNDKNQSEK--- +---TILDHQQL-LDKLPYYHRSGIRIANKTGELDK-VEHDCAIIEHEDET-IFIAVLTDQ +LTAN-QKGKEIIQLIGASIFE-- +>[subseq from] serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=UPI0012DE292B +--TLEKRIAAELYSYQGKMSVFVDDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAS +RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA +AMLGIFRQQHY-NTMLTHDFPQFLWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE +FHD-------------------- +>[subseq from] serine hydrolase n=1 Tax=Virgibacillus sp. Bac332 TaxID=2419842 RepID=UPI000EF50294 +----------------DHFSVYIET--NEGTI-SINPAQLRCAASLAKLPILIAGFRQLD +KNPHLQDKLVYIKRENMVGGAGVINYLSHSHYSYRNLLELMIIVSDNTAANVLLDIL-GV +ETINQLTKDADCQQSIIQRKFMDLQAK-ENGLDNYTSAYDIAKLLHLISENKFLTKESQK +MILTILANQQF-TNKLPSYLQDEIQFYHKTGELQ-GVTHDAGIMKYQDKT-IHVVLLSEG +IS-LNAESERIIADIGHLLIR-- +>[subseq from] Serine hydrolase n=1 Tax=Desulfofundulus salinum TaxID=2419843 RepID=A0A494WY98_9FIRM +-qPLQEQLKDYLAQQPGVYGIYFKDLHSGASF-DINGDEPITAASTVKVPVVLYLNHLVA +QGKLNWDDRVVYDSKDYQGGAGILQFSARDGYSLRVLANLSITISDNIAYRMLVRHL-GK +DNVARFMRDLGGQTV------------FPG-GENITTARDMGRYMEAVLEFSREHPALGE +RLLDDMANPIY-HVGLPGKLPPEVRVAHKEGDVW-GVANDAGIVFAE--HPYILVVLSRG +ET-DVDKGFARIAEISRMVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. KC723 TaxID=2530381 RepID=A0A4V2XBA1_9ACTN +---VRQRIRDIFARAGGSVHVVPVDGPDGREV-AVEADRQSVIASVFKILLVLEFARQAA +AGQLDPTERVVVTAADRLGGWGVAGCADDVEMSLRDLAYLTMSVSDNTAAELLLRRV-GA +DVLPMLAAELGLPRTRIVGGPRQLVEVFDPERTTSSTARELTRLLSLIWRDQAGPAAACA +TVRELMSRQLF-WTRLASGFPPGVRVASKTGTLP-GLHLDAGVAEYPDGSRYAMAVLVRT +ERLA-T----------------- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI0003AAE8E9 +---IQAQIEAVFADAGAEGFLHAREIGPGPEV-SAGGDAPVVLASVFKIPVALAYAREVA +AGRLDDTERTKVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVLYHRL-GQ +ETIDGVLADLGLARTRLIGCCEDLFAVRDPERTTSSTPREITELLDAIWTDRAGEPQACE +RVRTIMAQQIW-PHRLSSGFPSGVRVAAKTGTLP-GIRNEAGVVTLGDGRRFAVAVFTRA +HSDRLPAVDASIGAAARLAIDH- +>[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. N19 TaxID=2575512 RepID=UPI000E0FAA29 +--------ELAAQQRDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD +QGTLQWNEPLTLTEELVGGGAGWMASWPGSRFPTHEVATEMIRVSDNSATNLMIARAGGM +DAINARFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD +LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG +PFND-PRSTELIRQLVAA----- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. ISID311 TaxID=2601673 RepID=A0A5C6WGV9_9ACTN +---TQDHIRTAFADAAVTGWLHACDIDSGAEV-AFHPDHPVVTASVHKLCLLVALHQCAA +QGDFELTEQIEVPPTGRTFGLTGLGAMLDPAVSLRDAAYLMMSVSDNIAADLLLERV-GL +DAVNRTTTQLGLSHTLAIHTFRQLLDALDPARTNRSTPRDMTRLLSCIWRDEAGTPDHSA +AIRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA +ANATLPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Nocardia amikacinitolerans TaxID=756689 RepID=A0A285KTK6_9NOCA +----EERIREIFAELPVRGRFHAVDLADGREI-GVDADDQVVIASIFKILLILEFSRQVD +AGQLDPTERVLVRAVDRLGGWGTAGCADDVEMSLRDLAYFTMSVSDNTAADLLLRRI-GP +DTPALLAAELGLGATRVIGGPRQLLEVFRPEHTTSSTAREITRLLGMIWRDEAGSPAACA +ATRDLLRRQMF-WTRLAAAFPDEVLVASKTGTLP-GLHMEAGVLEYPDGGRYAVAVFARS +DETRRIDVDLAMARSARLAV--- +>[subseq from] Beta-lactamase n=1 Tax=Acetobacter indonesiensis 5H-1 TaxID=1231340 RepID=A0A0D6NG42_9PROT +---LAHQIEKTVLGQKGLFAVYAARVGARPEV-CQNCDHLINAASTIKLFVLDAAYKAFA +SGTLHPTDLIPVHNHSLVGGTFVLYAQQGKEVPVSELLRVMIQYSSNLATNLMIEKL-GV +FPIRDVVKEQALDGIVFGRMIEDFDAD-AQNIRNRVSARGLGEFLQKLDQGQIVGKEASQ +SMITIMLGQKF-NDIIPPGLPAGTPVAHKTGWVN-GVKNDAAIITLPDGSHYILVVLTSG +LP-DEAAGVKILNIISQEVYDYf +>[subseq from] Serine hydrolase n=1 Tax=Megasphaera stantonii TaxID=2144175 RepID=A0A346AYD2_9FIRM +-------------QDKAAVSVYCRPLDGGDDF--FYRDRVMPSASLIKVPIMACVFRQEK +EGQLSFDTTYPVYG--GVEGGSFYGLPEGTEVSLRTLVFHMIVESDNTCTNMLIDVL-GF +DAINEEIRRQGMEHTLLRRKMMDFEAA-RQGKENVTSPGDMGRLFLRLASGTCVDGRRDE +AMRAILAQQED-NCILPAQIPHTVTVEHKTGELD-GIYHDCGLVWKQGR-PYVCCLMADG +IV--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831) TaxID=221109 RepID=Q8ELZ1_OCEIH +--------------------VSIIVKTNNGII-RSKETKQMRSASIIKLFILASAYHLKE +KGKISLTDQIKLSSNDFVQGSGVISYLSDVKLTYQQLLELMIIVSDNTASNYLIERL-GI +PEIQAFIENLGCQQTRLERKFMDIEAQ-KLGKENVTSALDVIRLFDIFTENNFLGEKSQQ +HILSILKNQQF-NSKLTAYTEPLVTSYHKSGELK-GVEHDAAIFLKDNK-SFKVVVLTEG +WE-NNGDGQAFIASFGKVL---- +>[subseq from] serine hydrolase n=1 Tax=Acidobacteriaceae bacterium KBS 146 TaxID=639030 RepID=UPI0006919E3F +-qSLQQKLAALAATHKGHVTLYATQLNTGKTV-ALDADRPIQTASVIKLAILYEAMEQVR +EGKAHWEEKLTLAKGDGVNGSGVLTFFDTPLVTLKDVLTMMVIVSDNTATNLAIDRF-GV +GTINARIAWMGLNSTHLYKKIESMPADQPKFGLGKTTAHEMETIMERIGRGEPAQPGDTA +ICQTTMLRNQFYRNTIPRYLETGSGIASKTGSLN-AVRNDVAIVAGKSG-PIVISIFTDG +NQTADNEAEIIIARLAKEIVEAw +>[subseq from] serine hydrolase n=1 Tax=Acidobacteriaceae bacterium TAA 166 TaxID=278963 RepID=UPI0006942E21 +-qALEQRLQSLAATHRGHVSLYATQLKSGKTV-ALNADRPVQTASVIKLTILFEAMEQVR +AGKARWDEKLTLAKGDGVSGSGVLTFFDTPLLTLKDVLTMMVIVSDNTATNLAIDRF-GV +DAVNERIAWLGLKDTHLYKKIGKPATDQPKFGLGKTTAHEMEIVMERIGRERAADAAICQ +TAL-TMLRNQFYRNTIPRYLETGSGIASKTGGLN-AVRNDVAIVAGKSG-PMVISIFTTE +NETPDNEAEMMIARLAKEIMMAw +>[subseq from] Serine hydrolase n=2 Tax=Clostridium TaxID=1485 RepID=A0A2A7MKC5_9CLOT +------EIKRYLETRIGTYAFFFEDLESGYSF-GYNENVQMTSAGCMKLPIAMSVIKYVE +KGKASFLDKIKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIDIV-GI +DNINEDIDAMGLKNTKLNRKTSDERAA-SSGIENITSALDLSKVWKHLYNSTFLNEKDSI +MLADILQRQQM-KNKLALYIPDDYDISSKTGDKS-GVENDTALIHLQKGT-YTFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Uncharacterized protein n=2 Tax=Bacteria TaxID=2 RepID=A0A1F4UV06_9BACT +--NLNKQIDIQLKKLGGDAALMIKFLNTKEEI-KVNQEFQFWAASVIKIPISCEFFRQVN +EGKIKPETKTKIKAENRVEGSGVFKLLNKDDFTYLDLVTLMLDISDNAGTNEIVDII-GW +ENVEKYMHQLGLLNTTFRHKMMI--K--AGRGPNFTTAQDITMLLEKLYNNEI---PGAT +QILTILKQQQD-RRRIPLLLPNDIEISNKTGSLEK-AVHDAGIIYTKNP---FIFVFLSD +DQEDKILTNEVLSNCAKLCFDY- +>[subseq from] serine hydrolase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=UPI000C2605B6 +-qHVDAALTPLLAATPARVSLSLRDLDGGVVL-ARHADRMQPSASIIKVPILLALLEAVA +NGRYALEQPLALPAAERAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWNQRANLEATRLQRRMMDAAA-REAGRDNYTSAGDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVALAVLADG +FT--------------------- +>[subseq from] serine hydrolase n=1 Tax=Nocardia bhagyanarayanae TaxID=1215925 RepID=UPI001153A9A4 +----EERIREIFAELPVRGRFHAVDLADGREI-GVDADDQVVIASIFKILLILEFSRQVD +AGQLDPTERVLVRAADRLGGWGTAGCADDVEMSLRDLAYFTMSVSDNTAADLLLRRI-GP +DTPALLAAELGLAATRVIGGPRQLLEVFRPEHTTSSTAREITRLLGMIWGDEAGSPAACA +ATRDLLRRQIS-WTRLAAAFPDEVLVASKTGTLP-GLHMEAGVLEYPDGGRYAVAVFARS +DETRRIDVDLAMARSARLAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora echinospora TaxID=1877 RepID=A0A562DAA8_MICEC +------------ARVGVDARLHAVDIDTGHEV-GVDADEQVVIASVFKILLVLEFARQAA +NGQLDPTERVVVRAGDRLGGWGTAGCADDVELSLRDLAYFAMSVSDNTAADLLMRRV-GP +DLLPLLAAELGLTRTRVIGGPRQLLEVFDPKQTTSSTAREITRLLTMIWRDEAGPPAACA +MVRDLMSRQLF-WTRLPSGFPPDVPVAAKTGTLP-GLHIEAGVAQYPDGGRYAIAVFART +RRTRRIDVDLAMGEAARAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Catellatospora paridis TaxID=1617086 RepID=UPI0012D39836 +----TNRIADLFAGADMQGWLHARDLDTGREV-AVGADDQVVIGSIFKILLVLEFARQTA +AGSLDPADRMLVRAADRLGGWGTAGCADDVELSLRDLAYFTMSVSDNTAADLLLRRV-GP +DLLPLLAQELGLARTRLVGGPREILEVFDPGHTNSSTPEEITRLLGLIWRDEAGPAQACA +TVRELMFRQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHMEAGVVEYPDGGRYAVAVFAKT +ERLSMPELDLVLGRAAKLAV--- +>[subseq from] serine hydrolase n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=UPI0009DF09AC +---LERQIHELVEGVEGRISLNIEL--PAHTI-QLHSDVPYSAASLIKLPILLEGYRQIQ +ERKLDPEEVIPVTQEDKVGGAGVLSHLSPHTVTVHDLLTLMIIVSDNTASNLLIDRM-GM +DSINGMCRLLGLEQTKLNRRLMDFE-ALESGVDNHISATDAVKCLKGMENEVLFQLSCRE +SMIRILQNQQF-YQKLPGSMDNRVFTANKTGELP-GVEHDCAIIRYNQK-TVYAAVLIDE +LK-DGSEGSGLIMKVGKCLND-- +>[subseq from] serine hydrolase n=1 Tax=Agaribacter marinus TaxID=1431249 RepID=UPI0013ACF1DD +----------------DHFSVYIET--DEGTI-SINPAQLRCAASLAKLPILIAGFRQLD +KNPHLQDKLVYIKRENMVGGAGVINYLSHSHYSYRNLLELMIIVSDNTAANVLLDIL-GV +ETINQLTKDADCQQSIIQRKFMDLQAK-ENGLDNYTSAYDIAKLLHLISENKFLTKESQK +MILTILANQQF-TNKLPSYLQDEIQFYHKTGELQ-GVTHDAGIMKYQDKT-IHVVLLSEG +IS-LNAESERIIADIGHLLIR-- +>[subseq from] Serine hydrolase n=1 Tax=Nocardia stercoris TaxID=2483361 RepID=A0A3M2LH60_9NOCA +---------TIFRAAGAQGWVHARCLECAAEV-GSGADEPVVLASVVKVLLVLEFARQVA +AEQLDPTDRVRISAADRLGGVGTAGFFDDAEISLRDAAFMAITVSDNTAADLLFDRV-GV +ANVRSLVTELGLTRTRVLGAPRDLHTATDPLRTTASTPRDMTRLLALIDQDRAAPPDACS +WVRELMRRQVY-THRLASGFRPGTRIWSKTGSLP-GFRNEVGVVEDSDGFRCAVAVFTKV +DSVRMPMVDRAIGAVARAAVD-- +>[subseq from] serine hydrolase n=1 Tax=Jiangella sp. KE2-3 TaxID=1623398 RepID=UPI000E34CE20 +---------------GVTGFLHATDLASGAEA-GVDPDAPVVTASVFKIPVLVELCRQFA +AGERAHTDRMRVPAGGRTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR +ERINAGMAALGLPGTVLEEDCAGLFRVLDPETTNRSTPRETTTLLRRIWTADGLPEQACA +EARRIMGLQVW-PHRLTSGFPDDVKVSGKTGTLSH-VRNEVGVVEYPDGAAYAVAVFLRL +PGPANPAADAVIGTAARIAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Kitasatospora aureofaciens TaxID=1894 RepID=A0A1E7N7P8_KITAU +------------AEAGVTGLLHARDLDTGAEL-ALGADTPVSTASVHKLCLLVTLYREAA +AGRIDLTRPVDLPATGRTPGRTGLSAMLDAALSLRDLAYLALAVSDNAAADVLWDEI-GL +DTVNRTMAELGLTRTIAVHTVRELFAVLDPAFTNRSTAREMTALLAALWHGDACPGEPGA +ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA +AATSLPTADAAIGTAARLAVD-- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Prochlorococcus TaxID=2627481 RepID=A0A162CFT3_9PROC +---LSNRWRDLAKQQDLQASAFLLVLDDGRYA-ELSPETALPAASSIKTAILLVALELID +SGQLSWNEPLKLTKEIIGGGAGWMAKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGK +DVLNARFNALGLSSTVVNNWLPDLQGT------NTTSSHDLARAIALVDTGKALSPRTRD +LFREAMSTSVS-NRLLPGGFLKGYRIYNKTGDIGI-AYADAGLIELPDGSRAVAGFMVKG +PFND-PRSTELIRDMAAAM---- +>[subseq from] Class A beta-lactamase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=A0A1D8IGR0_9BURK +-qHVDAALTPLLAATPARVSLSLRDLDGGVVL-ARHADRMQPSASIIKVPILLALLEAVA +NGRHALEQPLALPAAERAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWNQRADLEATRLQRRMMDAAA-REAGRDNYTSAGDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVALAVLADG +FT--------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2W1AN95_9CHLR +-nSLQSSISDIIEGFSGIASVSANNLTSGDVL-SINETKILPALSTIKIGIMAELFFQIQ +EGKFKLTDRVTVQSSDIRGGTGVFRELQTPFVTIKDLCMMMIVVSDNTCTWMLCTRL-GK +DAINQRMRSIGMNEFSLNHDLQDMQGK-DVDAYSECSARDFTKLVTLMANGELVSKQASN +EMLDIMGRCQH-IEWLGRYLPPKVKLYNKVGAYLH-ARCDTGLIKSEKS-NYVITVFASY +SKDEPHEGSELIGKVSKVVYDAw +>[subseq from] Beta-lactamase n=1 Tax=Clostridium baratii TaxID=1561 RepID=A0A174S360_9CLOT +-----KEIKKYLESRIGTYGFFFEDLNSGFVY-GYNENVQMVAAGCMKLPVAMALIKDVE +LGKVTFMDKIRIDGADKVYGTGIIHEFDARDYTTFELLVAMLIQSDNTAANKIIDII-GM +ERINDYLKEMGLKNTVLNRKTADERKE-KPKVENLTTAKDLSMAWKILYDATFLSKENST +MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKP-GVENDTALIQLSKG-SFTFTVLSMS +IPNS-VYGTVTLAKSGKMMWD-- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A659B9A0_LACPN +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYSKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Serine hydrolase n=1 Tax=Nocardia sp. CFHS0054 TaxID=2382165 RepID=A0A386ZJA1_9NOCA +------------------GRVHARCVDCAGEF-GWGADEPVVLSSVVKVPLVLEFARQVA +AGQLDATDRVRATAATRLGGVGTAGCLDDVEYSLRDAARFALTISDNTAADLLFDRV-GV +ENVRSLVRELGLTRTRIVGSLRDILYAVDPLRTTASTAREMTSLLAAIATDRAAGPEVCG +WVRDLMRQQVF-GNRLPSGFPPGTDIWSKTGTMP-GIRNEIGVVGYPDGSRCAVAVFTVS +QLGRQPAVDRAIGEAARTAVE-- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Tsukamurella paurometabola TaxID=2061 RepID=A0A3P8MDF9_TSUPA +----AERIDAVFADAGCNGWLHARVVGHPAAL-SVRGAQAVVPASVYKVVLLVAAARAVD +AGRLDPRARITVDPAVSTPPTGIATLSDPVEMSVRDLLRSMVAVSDNAAAGVLMRLV-GL +AAVQEAARDLGLRGTRIVGGDAEIHAAYDPTFGSATTAADMTALLAAVWSDTAASAEQCA +FARSALAGQVF-RHRIASGFGSAPSIAGKTGTLG-ALRNEVAVVTYPGEHPVAVAVFTHA +ARNDLPRVDAAIGTVAAIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium paraputrificum TaxID=29363 RepID=UPI0012D28E49 +-----KEIKRYLESRIGTYGFFFEDLSSGFIY-GYNENVQMVAAGCMKLPIAVSLIKAVE +DKKVDFMDKISIEKEDKVYGTGIIHEFNEREYTIFELLVAMLIQSDNTAANKIIDII-GM +DNINSDIKEMGLKNTILNRKTSDER-QPKDGIENITSAYDLSKIWKHLHNATYLNRDNST +MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKK-GVENDTALIQLPKGN-FVFTVLSTS +VPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Serine hydrolase n=1 Tax=Streptacidiphilus sp. DSM 106435 TaxID=2126346 RepID=A0A345SX97_9ACTN +-------------------------------V-GIGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVLVTAEDRLGGWGTAGCLDDVELSLRDLAHFTMSVSDNSAADLLMARV-GV +DTVRLLARELGLDRTRIVGGPREVLRALDPLRTNASTPREITRLLGLVWRDEAGPPEACA +QVRDLMGSQVF-RHRLISGFPDEVVVAAKTGTLP-GLHIEAGVVHYPDGGRYAVAVFART +LDTGRAQVDAAIGTAARIAVEY- +>[subseq from] Putative beta-lactamase n=1 Tax=Prochlorococcus marinus (strain MIT 9303) TaxID=59922 RepID=A2C838_PROM3 +--TLSNRWKDLAKQQDLQASAFLLVLDDGRYA-ELSPETALPAASSIKTAILLVALELID +SGQLSWNEPLKLTKEIIGGGAGWMAKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGK +DVLNARFNALGLSSTVVNNWLPDLQGT------NTTSSHDLARAIALVDTGKALSPRTRD +LFREAMSTSVS-NRLLPGGFLKGYRIYNKTGDIGI-AYADAGLIELPDGSRAVAGFMVKG +PFND-PRSTELIRDMAAAM---- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. Wb2n-11 TaxID=1030533 RepID=UPI000A409244 +-----------------------------DEV-AVDADEPVVIASIFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAISVSDNSAADLLLAQV-GL +DTVRLLAEELRLDGTRIVGGPRDVLQVLDPSRTNASTPREITRLLRLVWRDEAGPPDACA +QVRELMARQVF-RHRLVSGFPDEVTIAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART +REASRPAVDAAIGAAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Arthrobacter sp. GMC3 TaxID=2058894 RepID=UPI000CE3956D +-----DQLADIFTAAGATGFVHAREIGDGPTV-SLNPDEPVVLASVFKVPFAVAYSREVS +AGRLEQTGRTTVTPRYRVGGLGTAGCDDDVEMSWRDLAKFMMTMSDNAATDVVFHRI-GQ +AAVDAVLDDLKLKHTTIIGCGEDMDIILDPARTPSSTPRDIVTLLDAIWTNAAGSVETCE +RVRSMMAQQIW-RHRMATGFDGNVLVAGKTGTLP-AIRNEVGVVTYPDGRHYAVAVFTKA +ATDPQPAIDASIGKAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus misasensis TaxID=392413 RepID=UPI000A03647D +------CLAELVLRFDGEVSLCVSDLQGELLF-VHEEHRVFKAASLIKLPILSCALEQVQ +QNGLSLQDRLAVSRENQVPGAGVLHEMETGLLTVQDLLTLMVVISDNTATNVLIEAL-GI +HTINQHIERIGLKNTFLVGKLEGQNEQQKAGQRSTTSAADMNLWLHKLVHTELLNPELGG +WATNVLKRQQD-RNVIARRLPRTFDVASKSGEISL-HRHDVGIVYAA--RPYVVCLLSRG +SKD-------------------- +>[subseq from] Beta-lactamase n=1 Tax=Prochlorococcus sp. MIT 0701 TaxID=1499502 RepID=A0A0A2CM72_9PROC +--KLSNRWRDLAKQQDLQASAFLLVLDDGRYA-ELSPETALPAASSIKTAILLVALELID +SGQLSWNEPLKLTKEIIGGGAGWMAKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGK +DVLNARFNALGLSSTVVNNWLPDLQGT------NTTSSHDLARAIALVDTGKALSPRTRD +LFREAMSTSVS-NRLLPGGFLKGYRIYNKTGDIGI-AYADAGLIELPDGSRAVAGFMVKG +PFND-PRSTELIRDMAAAM---- +>[subseq from] Beta-lactamase class A n=1 Tax=Microgenomates group bacterium GW2011_GWA2_44_7 TaxID=1618500 RepID=A0A0G1JN84_9BACT +-----EELGKLLSTYTGTYGVFVEDLQSGFSY-GVKEDEEFPAASQMKLPIILAVYLEYE +KGNLNLDAPYTLLKSDKIEGTSLASFKDGSNFTYRKLIEFSARNSDNSAIRILWRKL-GN +ERIRESLIVGGMKNSSFE--------------NDITTPKDIGNFFSLLYRDMLLRKEQKE +ELIGFLTNTIS-EDRIPAGLPAGTRVSHKIGTED-GAYSDSGIIFG--KKPFILVVMSKG +AN--FKEAPSAIAKIAQTVWS-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces vitaminophilus TaxID=76728 RepID=A0A0T6LWY3_9ACTN +----RARIREVFASAGVTGWLHATEVDGVHDV-AVDADTPVCTASVHKLCLAVTVQRLAD +EGRLDPREQVEVPAAGRTPGTTGLSVMQDPVMSLRDLLLLALTVSDNAAAQVLFERV-GL +EEVNRTTRSLGMRRTVAVHTPRDLVEVLDPARTSRSTPREMTSLLAALWRDEACSAGRAQ +ELREALALQVW-PHRLASGFPDDVRVAGKTGTLPT-LRHEAGVVEYPDGGRYAVAVFTRA +ARANQPAADAAIGTAARMAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Gordonia westfalica TaxID=158898 RepID=A0A1H2KNP3_9ACTN +-eQVDSDVTEILADAGCSGWLHATTIGSPQIShSYDADAPVVLASVYKLAVLISLCRSAD +RRDIDLAASITVDPTQWAQPTGLAALRDPVTLSRRDLATSMMTVSDNVAADVLLDEI-GL +DRVRDDLLDLGLRNTRIVGGVAELHEAYDAAYSSSSTPRDCTTLLTSVWTDRAASNEMCA +FIRDTMRRQVF-TSRLASGFPRRVTVAGKTGTLV-AIRNEIGVIEFPGELPVAVAVFTMS +ARSDLPHVDRAIGEAARTVVT-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. Leaf278 TaxID=1736319 RepID=A0A0Q6KIK8_9NOCA +--TTDEQLRAAFADAGCRGWVRAERIDGTGTVvDYEGDDPVVAASVWKIVLLVAAARAFD +DGSLTATDSVRLVPAQCSPPTGIASLADPVTMSWRDIARSMITVSDNAAADALLGAL-GL +DALTAVIEDLRLDQTRIVGGTKTLGEGFDPAYTSCTTPRDSNTVLRSIWLGTAASPTQCR +YMKQVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGEEPVAVSVFTRA +ARMDLPLVDRAIGHAARIAV--- +>[subseq from] serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=UPI0012DF6D05 +--TLEKRIAAELYSYQGKMSVFVDDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAS +RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL +DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSREASA +AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE +FHD-------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinopolymorpha cephalotaxi TaxID=504797 RepID=A0A1I2WYW3_9ACTN +-------IQQCFEDAGVWGWLHAVDLHDDREV-GFFPDEQVALASVFKLPLLAAYARMVD +AGEIDPVATVTLDPSRRTPGSTGFAAMADPIVSWRDLARSMITVSDNAAADELLDAV-GL +DRVRALLDDLGLRRTRITGGSRDLFDDPENPHSSVGTCRDMTRLLMAIWRDRAASPDQCV +YMRTVLTQQIW-TQRLAAAFPDDVVVAGKTGTFI-ALRHEVGVVEYPNGETYAVAVFTRS +PRTRLPAADAAIAQAAKIAVA-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces antimycoticus TaxID=68175 RepID=UPI0010F7E339 +---IEKRIAEVFAAADAEGRLHAVDIDPGRQL-GLGVDDQVVIASVFKILLVLEFARQAG +AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL +DTVRLLAAELGLDRTRIVGGPRELLEVLDARHTTSSTPRDITTLLGLIWRDRAGSPAACA +LVRELMSRQVF-RRRLASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART +ASAARTAVDAAIGRAARLAV--- +>[subseq from] serine hydrolase n=1 Tax=Gordonia namibiensis TaxID=168480 RepID=UPI0012F6C73A +--RVDRDVAEILADAGCSGWVHATTIGSPQIEhSFDADAPVVLASVYKLAVLISLCRSAD +RGDIDLASSITVDPTLWAQGPTGLAAFGDPVLSRRDLAISMMTVSDNVAADVLLDEL-GL +DRVRADLVSLGAERTRIVGGVAELHEAYDAAYSSSSTPRDCTALLSAVWTDRAASPEMCA +FIRDTMRRQVF-TARLASGFPRRVTVAGKTGTLV-AIRNEIGVVEFPGELPVAVAVFTAR +SEQSLPQVDRAIGEAARTVVT-- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium isatidis TaxID=182773 RepID=A0A343JAG2_9CLOT +-----KEIKKYLESRIGTYGFFFEDLRSGFVY-GYNENVKMVAAGCIKLPIAVSLIKAVE +DKKVDFLDKIKIERKDKVYGTGIIHEFNEREYTIFELLVAMLIQSDNTAANKIIDII-GM +DEINKNIKEMGMENTVLKRKTGDINNE-DDASENITSALDLAILWRHLYKKTYLSKENSQ +MLIDILNRQQI-KNKLALYIPDDYEISSKTGDKK-GVENDTELVTLSKGT-FSFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9ZG23_9BACT +------------------------------------------------------------ +------------------------------RVTNRDLATMMVAVSDNSATNVLIDRV-GM +ENVNAMMSGLGLTHTRLRRKMMDVRAA-SEGRENISSPREMMTLLEQIYRGKVLTKDLTQ +DFFRMLSTHKE--SFIPRDLPDGQRIANKPGELE-GVRNDSGIVFAQNR-PYVICVMTTY +LSR-ERSGEEAISKISAAAYAMf +>[subseq from] serine hydrolase n=1 Tax=Microbacterium oxydans TaxID=82380 RepID=UPI0009EA2548 +---VERRIAEIFAEAGATGFLHAREIGGGPEV-TVGADEPVVLASVFKILVLTAFVRAVA +AGELDPAARTTVTARYRIGGVGTAGFADDVEMSWRDLALNMMTMSDNAATDVIYHRL-GA +EAIDRVISELALRQTQLVGCCEDLFAAVQPLRTSHSTPREVTAVLNALWTDAAAAPEACR +QARDIMALQIW-PHRLTSGFPAEVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA +ASLS-DRQPLVDASIGRAAF--- +>[subseq from] serine hydrolase n=1 Tax=Pedobacter sp. HMF7647 TaxID=2695275 RepID=UPI00136D673B +-kKLQGKLVELTKGINGVAGIYVKNLNTGKIA-VFNADSIFPTASMIKVPIMAGLFEKLD +RGDLNYSDIWQYRDSLSYDKGDVVGSLADSAINLSKVQMLSITTSDNTASLWIQKIV-GG +ENINNWLDKNGFKDTRVNSRTPGRQANQKLYGWGQTTPREMATLVEMIRNGKAVSEAASE +RMYRNMSHIYW-DDKALSQIPPTVQTASKQGAVD-ASRSEVVLVNAPHGD-YVFCIITKN +LATPSNEGWQLIVKTSDLLWHYf +>[subseq from] Serine hydrolase n=1 Tax=Dyadobacter sp. AR-3-8 TaxID=2576211 RepID=A0A4U6D344_9BACT +-kKLTGKLEKALAGFKGNAGIYVRNLKSDKFA-SINADTIFPTASMVKIPIMIGVFDKIN +KGQIQFDQLLTYRDS-LKYDDGITGSLRDSTIPLPKVIHLMISLSDNTGSLWLQALAGGG +STINQWLEINGFINTRVNSRTPGRKQNQAMYGWGQTSPREMAELMAMLRLGKVISPDASE +RMYRYLGMQFW-DGEALSQIPPFIKTGAKSGAVNQ-AKSEVVMVHAPHGD-YVFCITTKN +QQQRDNEGYKLIRTVSEIIWNHf +>[subseq from] Serine hydrolase n=1 Tax=Bacillus kyonggiensis TaxID=1037680 RepID=A0A4U1D7B9_9BACI +---LVERIDELIRLCPGRISLQGEI--GDWSY-EHDSERMYSSASLIKVPILIEAFRQYE +NGVFSLGDFVEIRKDLRVGGSGVIQALEQSSWMIKDLKTLMITVSDNTATNMLIELL-GI +DSVNDSIELLGLKKTKLQRKMMDFSA-VQEGKDNYTCAADMIRCLKVIDESGFLKEESCR +EAKLILRHQQF--HKILGLLQEQGYMGSKSGSLP-GVEHDCAIIGVQGKT-AYVAILIDQ +IPE-GKSGTLTMQEIGRAVYDA- +>[subseq from] Beta-lactamase n=1 Tax=Microbacterium sp. Ag1 TaxID=1643443 RepID=A0A0M3D2Y2_9MICO +---VERRIAEIFADAGATGFLHAREIGGGPEV-TVGADEPVVLASVFKILVLTAFVRAVA +AGELDPAARTTVTARYRIGGVGTAGFADDVEMSWRDLALNMMTMSDNAATDVIYHRL-GA +EAIDRVISELALRQTQLAGCCEDLFAAVQPLRTSHSTPREVTAVLNALWTDAAAAPEACR +QARDIMALQIW-PHRLTSGFPAEVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA +ASLS-DRQPLVDASIGRAAF--- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetes bacterium Spa11 TaxID=2528022 RepID=A0A518K6V3_9BACT +-------ILDLAQSTPARVGLAVESLDGAWSY-SVLPDEVFAQASAIKVPILWELHRAAA +AGELSLDERLTVDPANGAGGCGMLQNFLPGAMALGDLGVAMIVLSDNVATNLLIDRL-GF +DAVNALLVSQGANQTRLRRKMIDPEA-RKAGRENTSTPSEAVRLMRRLHDAEGAGDPVAA +AVLKVLRLRKE--SPVTTVLPSDTRLATKPGMLD-GLRTEWSIVEREGV-NYAMALMVDG +GDE--ILIDALVREIAV------ +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. TMED20 TaxID=1986597 RepID=A0A424HLP6_9SYNE +-----------AQQKDLKTSAFMLILDDGRFA-QLEAERPMPAASSIKTPILLASLEXXD +NGDLHWNEPLILTKELIGGGAGWMAKPVGSRFPTYEVATEMIRVSDNSATNLLIERVGGQ +XAXNARFQALGLXATEVNNWLPDLDGT------NTTSARDLSRSIALVDSGETLSPXSRD +LFREVMSTSVT-DTLLPTGLLQGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVQG +PFN-DPRSTDMIRALAKAMA--- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6GUH8_9BACT +-kKLETRVEEIAARLDGVMGVAILDLSDGRVL-LRNADRVFPAASSIKLAILLELYRQDQ +QGKAKLDDIYAFDPKDLVEDSQIMAGLTPGVVTNRDLAQFMVAVSDNAAANILYDRV-GR +DNVNALLRGLGLSKTTLRRKMMDIAAARRG-DENVATPQEMIRLLEAIYKEKALNKQSTA +EFIKQ------------------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Nocardia bhagyanarayanae TaxID=1215925 RepID=A0A543EY66_9NOCA +----EERIREIFAELPVRGRFHAVDLADGREI-GVDADDQVVIASIFKILLILEFSRQVD +AGQLDPTERVLVRAADRLGGWGTAGCADDVEMSLRDLAYFTMSVSDNTAADLLLRRI-GP +DTPALLAAELGLAATRVIGGPRQLLEVFRPEHTTSSTAREITRLLGMIWGDEAGSPAACA +ATRDLLRRQIS-WTRLAAAFPDEVLVASKTGTLP-GLHMEAGVLEYPDGGRYAVAVFARS +DETRRIDVDLAMARSARLAV--- +>[subseq from] Beta-lactamase class A n=2 Tax=Peptococcaceae TaxID=186807 RepID=A0A1M4YVG1_9FIRM +-qPLQKQLKEYLARQPGVYGIYFKDLHSGVSF-DINGDEPVTAASTVKVPVVLYLNHLVA +QGKLDWDDRVVYDSKDYQGGAGILQFAARDGYSLRVLANLSITISDNIAYRMLVRHL-GK +DNVAQFMRDLGGQTV------------FPG-GENITTARDMGRYMEAVLEFSREHPALGE +RLLDDMAHPIY-HVGLPGKLPPKVRVAHKEGDVW-GVANDVGIVFAE--HPYILVVLSRG +ET-DVDKGFARIAEISRMVYDY- +>[subseq from] Uncharacterized protein n=1 Tax=Megasphaera sp. ASD88 TaxID=2027407 RepID=A0A2A2IL95_9FIRM +-------------QDKAAVSVYCRPLDGGDDF--FYRDRVMPSASLIKVPIMACVFRQEK +EGQLSFDAAYSVYG--NVEGGSFYGLPEGTEVSLRTLVFHMIVESDNTCTNMLIDVL-GF +DAINEEIRRQGMENTLLRRKMMDFEAA-RQGKENVTSPGDMGRLFLRLASGTCVDGRRDQ +TMRAILAQQED-NCILPAQIPNTVAVEHKTGELD-GIYHDCGLVWKQGR-PYVCCLMADG +IV--------------------- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CB00013 TaxID=1703945 RepID=UPI00093BAFDD +---IRVRIEAVFAAAGAEGSLHAREIGDGAEV-SVGADDQVVLASVFKIPIALAYAREVV +AGRLDETECTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWNRI-GQ +ETICRVVADLGLTRTRLIGSCEDSFRMCDPERETSSTPRETTELLDAIWTDRAGEPEACQ +RVRAIMAQQIW-PHRLSAGFPSDVRIAAKTGTLP-GIRNEAGVVTLPEGRRFAVAVFTRA +HSDRLPEVDASIGAAARLALDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Lentzea violacea TaxID=128104 RepID=A0A1G8QKQ5_9PSEU +--------------AGVEGFVHAREIGDGPEA-GHGADEQVVLASVFKIPVAVAYAAEVA +AGRLDEMARTRVTPRYRIGGIGTAGCRDDVEMSWRDLALFMMTMSDNAATDVVFHRV-GQ +AAVDAVVA--GLPRTRILGCCEDLFAIVDPERTTSSTPREITTLLDAIWTDRAAAPEACE +RVRAIMAQQIW-PHRLSSGFPADVLVAAKTGTLP-GVRNEAGVVTYPDGRGYAVAVFTRS +QSLDNPAADAVIGRAGRLAVDQ- +>[subseq from] Uncharacterized protein n=1 Tax=Firmicutes bacterium ADurb.Bin467 TaxID=1852894 RepID=A0A1V5KEN4_9FIRM +-----------------------------DPV-AINADMPLIAASVIKIPVMIEAFRQFE +AGLLSPDMAVTVRPEHRMPCGALAYMHDNLTVTAMDCVTLMIILSDNTATNLMIDML-GI +ENINSTLAALGCVQTRIARKLFDREG-MKRGLKNFITAREIGMLLEKIYRGEAVSPAASE +TMLEILKNQRL-NGKIPFFLHLGVKIAHKTGEED-GISHDAAIVFAD--RPFSMVALSNN +VDV--PMYERLIQDAALALYR-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI00084FA5EF +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGIGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] serine hydrolase n=1 Tax=unclassified Amycolatopsis TaxID=2618356 RepID=UPI00106E207D +---ASETIARRAEEVGVEVRLHAAEVDGTRSL-GIGEDVPVVPASVFKVPIALELARQAA +EGTLDLGAPVTVEPGHPTPPYGLATFRHEVRMSWHDLAILMIGISDNVATDLILAEV-GK +DAVNSTLRRLGFTQTVVPQDCGELLAALQPEKSCRTTAAEMTRLLGLIWRDEAAAPEACA +DVRRWMELQVW-PHRLRSGFPDGIRTSGKTGTLP-AVRNEVGVVEYPDGGRYSVAVFTRA +EDSRVPERDAFIGFAAATAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardia brasiliensis ATCC 700358 TaxID=1133849 RepID=K0F6C5_9NOCA +----------IFRNAGAQGWVHARCFGCAGAN-GLDADEPVVLASVVKVPLVLEFARQVA +AGQLDPADRVRARAADRLGGVGTAGCFDDVELSLRDAAFFALTLSDNTAADLLFDRV-GL +DNVRSLVRELGLTETRIAGAPRDIVQALDPRRTTASTPREMTRLLTLIGQDLAGPAQACQ +WVRDVMREQVN-WHRLAAAFPPEAQIWAKTGTLP-GVRNEIGVIEYPDGSRYAVAVFTRT +ESQRLPEVDRAIGAAAVAAID-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces viridosporus T7A TaxID=665577 RepID=A0A5J6FZ61_STRVD +-----------------------------REV-AVGADDPVVIASIFKVLLVLEFARQVV +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNTAADLLLARV-GP +DTVRLLARELGLERTRIVGGPRDLLEVLDPRHTTASTPREITRLLRLVWSDAAGPPEACA +FVRDLMIRQVF-RHRLASGFPDDVAVAAKTGTLP-GLHMEAGVARYPDGACYAIAVFART +RDVSRATVDAAIGRAAGI----- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces gardneri TaxID=66892 RepID=UPI00142F0073 +haAARRRITAAFADAGVTGLLHAVDIDTGTAL-GIGSDTLVPTASVHKLCLVATLYRQSS +LGLIDPTRPVEIPAEDRAPGATGLSVMRDAALSLRDLASLAVAVSDNTAADLLWDAL-GL +DTVNATMTGLGLTRTHAVQTMRELFAALDPTRTNRSTPREITALLAAVWRDEVCAGEYGE +ELRALLGLQAW-SHRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA +ASTDLPAADAVIGGAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora alkaliphila TaxID=1783498 RepID=UPI0013BDA7B0 +----VAQLDAAFSGAGVSGYLHAAEIDGAADV-GYAADELVVTASVFKIYVLLELCCQAA +EGRRSLTDRVRFAPEARTPPTGLSVMYDEIDMSVRDAAYLMMSVSDNHATDVLMGLA-GV +DDIHRRLRALGLPRTAAPHTCAELFRALTPAMTNRTTARETTSLLGMIWRDENLPAGACA +ETRRIMGLQVW-PHRLTSGFPHGIRVSGKTGTLSH-VRNEVGVVEYPDGGRYAVAVYLRV +SDRANPAADAVIGQAARIAVDH- +>[subseq from] serine hydrolase n=1 Tax=Megasphaera sp. SW808 TaxID=2530045 RepID=UPI00143A252A +-------------QDKAAVSVYCRPLDGGDDF--FYRDRVMPSASLIKVPIMACVFRQEK +EGQLSFDTTYPVYG--GVEGGSFYGLPEGTEVSLRTLVFHMIVESDNTCTNMLIDVL-GF +DAINEEIRRQGMEHTLLRRKMMDFEAA-RQGKENVTSPGDMGRLFLRLASGTCVDGRRDE +AMRAILAQQED-NCILPAQIPNTVAVEHKTGELD-GIYHDCGLVWKQGR-PYVCCLMADG +IV--------------------- +>[subseq from] Beta-lactamase class A n=2 Tax=Jiangella alba TaxID=561176 RepID=A0A1H5MIJ7_9ACTN +-----DDIAAALRRAGTDAALHVRPVDGPGEV-ALNPDAVSVAASTYKIAVLLELACQAA +EGTLSLTARQRVPAGRRSLPTGISAMLDDVDLSLRDLALLMMQVSDNTATDVVQEVV-GT +DRITARLKGLGLANTSFPHDCAKLVGSIAGTVGNTTTPRDMTTLVSAIWRDEAGPAEACE +EVRRIMAQQYA-PHRLSTAYRDGPAIAGKTGTFHGGIRNEVGVVDFGGGDRYAVAVYLRQ +HEYDDGAADAVIGEVARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. S14-83 TaxID=2489213 RepID=A0A3G8YRV9_9DEIO +-----------AQSYGGEVGLAISTLEGEVLV-CLNAERAFLSASTIKVPLLLLALERVQ +TGQLRLNERHTLKPADRVGGAGILHELGAGLLSLEDLLTLMIIVSDNTATNMVIDLL-GV +DAVNAWLFERGCRQTRLVGKLEQQNAAQLLGERNRTSAAEQAELLLGLWQGQRLEPPVRQ +LALSILGRQHYRDILGRSLLRSRYQTYTKSGELL-GVHHDVGLLLLP--RPLCVALLSEG +GSDR------------------- +>[subseq from] serine hydrolase n=1 Tax=Embleya scabrispora TaxID=159449 RepID=UPI00037A21DE +-----KTIRDIFDAAEVDGYLHVRDLDGDDEV-DYRADAPVVLASVFKIPIALEYARQAA +AGRLDRAGRHVVTDADKEGGIGTDGCMHDVEMSARDLAYMMMTMSDNAATDMVLGLV-GR +ENVRATLDELGCHDTSVTGCKELFASVRDPEHTASTTPREITKLLAAIWRDEAGPAEACA +EVREIMGRQIW-PHRLSSTFGDEIRVSGKTGTLW-GVRNEAGVVEYPDGKRYAVGVFLRS +ESFRLPRADAAIGLAARAAIDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2570 TaxID=2512221 RepID=A0A4R7ZM59_9ACTN +----NARIRAVFDDAGVRGWLHAVALDEPESTvEVDADGIVPLASVYKLPLLAGFCRLVD +LGEVDPRERITLDPSAKTEGPTGLSMFADPVVSLRDLALSMMTVSDNASADALLDIV-GL +RRLAGMLESFGLHRTWVRRGTAGNLRVYEAANASASTARDMTLLLQRLWSGELLSPEQTD +FVKTTMHRQVF-LHRLASGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGEAFAIAVFTLA +ARNRQPRVDTAIGQAARLAVD-- +>[subseq from] D-alanyl-D-alanine carboxypeptidase n=1 Tax=Oceanobacillus oncorhynchi TaxID=545501 RepID=A0A0A1M5T2_9BACI +--------------------------SGENEI-AFNENKPLRSASIIKLFILAAAYYEEE +KENIDLSKQVHLSPSDMVGGAGVIPYLSDKQYTYQQLLELMIIVSDNTATNALIDFI-GL +DTIHAFIQQIGGKHTKLERKLMD-EEAIKLGLENRTSCYDVMLLLDLLTENNILPKHRQE +QMLTILENQQF-NSKLTAAYDSSIKTFHKTGELT-GAEHDAAIFQTADKQ--LKAVMLTE +GWTNNGEGQQFHQRAGAHIYHY- +>[subseq from] Beta-lactamase n=2 Tax=Prochlorococcus marinus TaxID=1219 RepID=A0A163PE06_PROMR +--KLSNRWRELAKQQDLQASAFLLVLDDGRYA-ELSAETALPAASSIKTAILLVALELID +SGQLSWNEPLKLTKEIIGGGAGWMAKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGK +DILNARFNALGLSSTVVNNWLPDLQGT------NTTSSHDLARAIALVDTGKALSPRTRD +LFREAMSTSVS-NRLLPGGFLKGYRIYNKTGDIGI-AYADAGLIELPDGSRAVAGFMVKG +PFND-SRSTELIRNMAAAM---- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces exfoliatus TaxID=1905 RepID=UPI0010FB6E26 +--AVRTRITAAFTDAGVTGQLHATDIDTDAAI-GVGSDVTVPTASVHKLCLIATLYREAS +LGRLDLRRPVDIPAEGRSPGATGLAMRDAARLSLRDLATLTVAVSDNTAADLLWDAV-GL +DTVNRCMTDLGLTRTVAVQTMRELYAALDPALTNRSTPRETARLLAAIWRDEVCAGERAA +QLREVLGLQAW-SHRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA +AAVTLPAADAVIGRAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. SID8362 TaxID=2690346 RepID=UPI001414F4FF +---------------GARGFLHAKEIGGGGEV-AVGADDPVVLASVFKIPVAVAYAREVV +AGRLDETERTRVGKRYRIGGIGTAGCADDVELSWRDLALFMLTMSDNAATDVIYHRV-GQ +AAVDRVLADLGLGRTRLIGCCEDLFAVLDPERTTSSTPREITTLLDAIWTDRAGEPAACE +RVRAIMARQIW-PHRISSGFGSDVAIAAKTGTLP-AVRNEAGVLSYPDGRRFAVAVFTRA +DSERQPAVDAAIGKAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces antimycoticus TaxID=68175 RepID=A0A4D4KEK1_9ACTN +----EKRIAEVFAAADAEGRLHAVDIDPGRQL-GLGVDDQVVIASVFKILLVLEFARQAG +AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL +DTVRLLAAELGLDRTRIVGGPRELLEVLDARHTTSSTPRDITTLLGLIWRDRAGSPAACA +LVRELMSRQVF-RRRLASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART +ASAARTAVDAAIGRAARLAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces paucisporeus TaxID=310782 RepID=A0A1M7H351_9ACTN +---ARGRIQAAFADAAVTGWLHARDIDSGAQV-DAGGDQEVCTGSVHKLCLLVALHHAAA +EGRLDLAEQTECPPAGRTPGPTGLAAMLDPVMSLRDMAYLMAAVSDNAAADALLERV-GL +DAVNHATARLGLTRTRAVHTFGEILTALDPAGTNRSTPREMTGLLGAVWRDEACTPEHGA +AIRRLLALQVW-PHRLASGFPDDVRVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT +PNATLPAADAAVGTAARIAVD-- +>[subseq from] Secreted beta-lactamase n=4 Tax=Streptomyces TaxID=1883 RepID=D6BBB4_9ACTN +----------------------------EGEI-ALGADEPVVIASIFKVLLVLEFARQVA +AGQLDPRERVRVTRGDRLGGWGTAGCADDIELSLRDLAFFAMTVSDNSAADLLLARI-GL +DTVRLLAGELGLDRTRIVGGPRDVLEALDPLRTNASTPREITRLLRLVWQDEAGPPQACS +QVRELMARQAF-RHRLVSGFPDGVAVAAKTGTLP-GLHMEAGVIRYPDGGLYAVAVFARS +REASRTEVDAAIGATARIAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Kutzneria albida DSM 43870 TaxID=1449976 RepID=W5W3B5_9PSEU +---TSEDLAALFDRIGARGWVHARELDGDREI-GLDPDEPVVLASVFKLPVLVTYLRAVA +AGELDPAERVRIGPRHRIGGIGTAGCADDVEMSWRDVALFMMSMSDNAATDVLLARL-GL +DRVHEVLASLGLTRTRLIGGCEDLFAVYDPERTTSGTPREITSLLAQVWPDP-------- +ELRAVLGKQVW-PHRLSAGFPDEVAVAGKTGTIP-GLHNEVGVVTYPDGRAYAVAVFTRS +ASHRQPALDAVIGASARAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Flavisolibacter sp. 17J28-1 TaxID=2502779 RepID=UPI00104A609F +-kKLQQAIEQMAVGFGGQVGIYVKDLHSGKVA-AYNADTIFPTASIVKIPIAVGIMQKLE +RGELTYHQPLVYKDSLLYPGVDILGSFKNGEIDLSKVLMLMLTTSDNTASLWLQSLAGGG +TTINVLMDTLGFPQLGVNSRTPSREADREVYGWGQMTPRAIAGLMEEIYRRRVISPAASD +RMLRLLNRNYWDAEALSEIAP-YAAVFSKNGAVNE-SRSEVVLVRGKKSA-YLFCIATKN +NHTPANQAWTLTRKLSAYLWQHf +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6NI39_9BACT +-kKLEAHIDEITERFDGVMGISIVDLTDDRAI-LKNAGHVFPTASSIKIAILLELYRQEQ +QGKAKLDDIYTFEAKNLVDGSQIMTGLTPGVLTNRDLAQFMVAVSDNAAANILIDRV-GM +QNVNATLRNLGLTKTMLRRKMMDIAAARRG-DENVSTPQEMTRLLEAIYKGKALDKELSE +IFMK-------------------------------------------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=candidate division WWE3 bacterium CG08_land_8_20_14_0_20_41_15 TaxID=1975086 RepID=A0A2H0X8V3_9BACT +---LKKAIEKEIKGANGKYGIVVKNLKTGESC-FANEHMKFEAASLYKLWVMATVFNQIQ +EGKLSKNEVLSREVEELNRDSEVAELTEGTILSVEDALAKMITISDNYAALLLAKRI-GL +SIVQTFLKDNLLEESIIG--EP-----------PITTAYDVALFFEKLYNGELANQENTK +LMLNLLKGQLL-NHKLPKYLSEEVTVAHKTGELGI-FSHDAGIVYGEKGD-YIIAVLSES +DD--RLAAEEQIAKISKSVYEYf +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535K8V7_9CHLR +--ELIQRLDGLLASFPGGAGIWVADPSVTTPLfTHDPEEQVIAASLYKLGVLAEAERRVD +AGELHYDDTITIEPEDITADGSF--EDAGTHLTLDEALEAMITISDNGSALALWHIL-GG +ANIDATLEKAGVKNFHVA---------FDDTEDNWATPHAVGTFLTLLAKRQLISPAASD +RMLARLERQQI-NDRLPAQLPPDVVIAHKTGNLS-GVLHDAGIIYTKTGPR-VVVAMTWD +AP--EEEAANFISSIGSLVYS-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00041DB577 +----------------DHFSVYIET--DEGTI-SINPAQLRCAASLAKLPILIAGFRQLD +KNPHLQDKLVYIKRKNMVGGAGVINYLSHSHYSYRNLLELMIIVSDNTAANVLLDIL-GV +ETINQLTKDADCQQSIIQRKFMDLQAK-ENGLDNYTSAYDIAKLLHLISENKFLTKESQK +MILTILANQQF-TNKLPSYLQDEIQFYHKTGELQ-GVTHDAGIMKYQDKT-IHVVLLSEG +IS-LNAESERIIADIGHLLIR-- +>[subseq from] UPI00143EC2E6 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00143EC2E6 +-qSLKSNLESIIKDKNATIGVSVWNLEKGEKT-SVNGDSNLPMMSVFKLHIAMTILDLVD +GGTLKLDQKIKFSKSELMQWSPMRDKYPNGGIPLSEMIKYVVAQSDNNTCDILLNKIGGL +KTVENYIHKIGVTDFWAVANEKMMHKVDGAIYKNLTTANASNLLLTKLYT---------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium RBG_16_64_32 TaxID=1797658 RepID=A0A1F8RIZ5_9CHLR +--ALAALIRTTLSGYAGTYSVVVRNLDDGRSA-SWNAEEVYTAASLFKLALLLEAYRQRD +SGEIDFSEVLTLDEEYVEYNFGTLEAEEGDQLTLADALKAMIIVSDTPTAVMVQDVV-NP +VRVDQTLRSLGINDMSVLTEE--LP----------TTARDMALLMEAVAAGQGVTDESRR +QMLGLLLQESI-RGGIPSGVPPNSAVAHKTGNLDN-LTHDVALVWGPGG-PYVIAVLSDR +SWES-----EPLATVSRAVWDYf +>[subseq from] Serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A6A1YS71_LACPN +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDIKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] serine hydrolase n=1 Tax=Sporosarcina sp. ZBG7A TaxID=1582223 RepID=UPI0009DFE7B0 +--QLKEELDRIANNAVGDVSIYATT--PEGVI-AIREDEVKRSASILKVPVAMACLAAAD +RGEIDLDTLLKIEE--PVGGSGVLAYMSGMEITLRNALTLSIIVSDNTAANLVIEHV-GI +ERIQKFFKHVGATHSQLTRKFMDYD-ALARGLENVATAKDMVRFLMCLDPSENLSLTSKQ +QLKTIMRDQQL-IDKLPAFQPETLIIGNKTGTLP-GVEHDIAYFENGER-CVNIAVLTTD +WEYN-HDGQQTLAQIGKSIIKY- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora chersina TaxID=47854 RepID=A0A1C6V032_9ACTN +-----ERIGEIFQRAGISGCLHVVDVDPGREV-ALRADEQMVIASVFKILLVLEFARQAV +AGQLDPAERVVVDAADRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DVLPMLAAELDLPRTRIVGGPRQLVEVFDPDHTTSSTAREITRLLGLIWRDEAGPPAACA +LVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVVEYPDGGRYAVAVFART +ERLSTRDVDLAMGDAARAAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter sp. OK283 TaxID=1881049 RepID=A0A1H8RJG6_9SPHI +-kKLTAQLQDAVKGFHGQAGIYVQNLKTGKTA-AINADTLFPTASMIKVSIQCGLMDKIE +KGELHYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GG +NYINNWLQQNGFKAMRVNSRVAGREAIRKIYGWGVSTPYEMCRMFTMIRKGEAVSPAASE +RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH +NTGTSNEAGLLIKKISALLWHYy +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Microbacterium oxydans TaxID=82380 RepID=A0A3Q9J5F1_9MICO +---VERRIAEIFADAGATGFLHAREIGGGPEV-TVGADEPVVLASVFKILVLTAFVRAVA +AGELDPAARTTVTARYRIGGVGTAGFADDVEMSWRDLALNMMTMSDNAATDVIYHRL-GA +EAIDRVISELALRQTQLVGCCEDLFAAVQPLRTSHSTPREVTAVLNALWTDAAAAPEACR +QARDIMALQIW-PHRLTSGFPAEVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA +ASLS-DRQPLVDASIGRAAF--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces viridifaciens TaxID=48665 RepID=A0A1L9DWF6_STRVF +-------------------LLHARDLDTGAEL-ALGADTPVSTASVHKLCLLVTLYREAA +AGRIDLTRPVDLPATGRTPGRTGLSAMLDAALSLRDLAYLALAVSDNAAADVLWDEI-GL +DTVNRTMAELGLTRTIAVHTVRELFAVLDPAFTNRSTAREMTALLAALWHGDACPGEPGA +ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA +AATSLPTADAAIGTAARLAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Plantibacter sp. PA-3-X8 TaxID=2480625 RepID=A0A3G8VM47_9MICO +---IAARIESVLEPLGVRGYVHAVDIDSGVEV-GLDADTDVVTASVFKLPVLVELARQYE +AGALDPRRRIRVGADERRTDGPTLSILLDDVLSLRDLSVLMMSVSDNRATDLITDLV-GL +DSVNATMRSFGLERTVVPVDCDALFRVSNPESNDRTTPREITTLLAAVWRDEVIGAAAAA +EVRRVLGLQAW-SHRLVAGFPSRVKVSGKTGTLFF-IRNEAGVVEYPDGGRYAVGVFLRE +SSLRHPDADRAIGTVARVAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536DJM1_9CHLR +--ELDRRIATLQRGFQGQLGLAATNLATGEQV-LVNADQLFPTASVIKVSVLAELFAQAE +EGRLMLDERLQMQASHIVGGSGVLRELLPGLPTLTDLAMLMVVLSDNTATNMLIDRLGGC +DVINRRVQGYGFASVALHNRVDFEKIGSDVRRFAEATPADLARFMERLAREELVSASASR +KMLRIMSRQQYLD----------------------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=UPI00040FBEFC +--------------------------QTHETL-TREPDRVMETASVIKLPIMAATFQYLA +DEHKTLSEPLTLQVEDMVDGSGILQHLSPGLLSIKDVMTLMIIVSDNTATNMILRQV-GI +PRVNRFIQSLGLSQTRLLKRIDF---TIPG-PIGLATSRELGMILTQLYHRTLVNKDASD +IMWDILCRQQY-NTIMTRHLPPKVQIGSKSGSLE-GIRNDVGIITTPWGD-YVLAILSEH +SRHIDNEALVILPQLSRIIFDYf +>[subseq from] hypothetical protein n=1 Tax=Heliobacillus mobilis TaxID=28064 RepID=UPI0012D77217 +-qVLKQRVQGYLDERPGQVSVYVQDLTTGASF-DIGGDQIYMTASTHKLPTVLYLYTLAA +QGKVDLNSTLTYTSDYYRQGTGIMQGEPGKEYKLRELARLAIVYSDNAAWAMLLDYL-GD +DNLGQFEQSIGGTVTYYDDNSNPL-----------TTPRDMGKYLAYLSVFRDNQPALGN +EIFNALENTVY-NDRIPSELPAGTVVAHKIGSLND-KFHDVGIVFAPNR-PYIISIYSKD +GW--EAASVQTLADLSRIVYDY- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2N5K906_9CHLR +------ALTTLLDQAPGRYSVCVG-TATGVPIyDYAGKVVRSAASLIKVPLALAIYDTLP +---HRLDEPVTLREGDRVAGEGSFDGAPPGTRTVRELIGHALRESDNTAANLLIERI-GF +EAVNHWLVARRL-QTRLQRKFMDFDA-LHAGRDNLTTAADMCVLLLALL-----QPRYAD +LL--AMLRQAVGTGKLEAGLPPGTFIAHKVGDLP-GVEHDAGIIFAANG-PYLVAVLAVE +LQ-DAAAGRHTIAEVSRLVWE-- +>[subseq from] Beta-lactamase n=2 Tax=Prochlorococcus sp. MIT 1303 TaxID=1723647 RepID=A0A163E7C0_9PROC +--TLSNRWKDLAKQQDLQASAFLLVLDDGRYA-ELSPETALPAASSIKTAILLVALELID +SGQLSWNEPLKLTKEIIGGGAGWMAKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGK +DVLNARFNALGLSSTVVNNWLPDLQGT------NTTSSHDLARAIALVDTGKALSPRTRD +LFREAMSTSIS-NRLLPGGFLKGYRIYNKTGDIGI-AYADAGLIELPDGSRAVAGFMVKG +PFND-PRSTELIRDMAAAM---- +>[subseq from] serine hydrolase n=1 Tax=Clostridium tarantellae TaxID=39493 RepID=UPI00128C74EB +------EIKKYLESRVGIYSFFFEDLASGYTY-GYNENVKMISAGCMKLPIAVALIKEVE +EKKLDFLDKVKIESKDKVFGTGIIHEFGEREYTVFELLVAMLIQSDNTAANKIIDMV-SM +EKINIIIKELGLKNTELNRKTAD-ERNYHDKLENYTSSYDLCLIWKNLYNGSFLNKENSQ +MLIDILERQQI-KNKLALYIPDNYDISSKTGDKQ-GVENDTALIHTSKGN-FICTVMSSK +IPNS-VYGTITLAKSGKMMWD-- +>[subseq from] hypothetical protein n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI00062A12FE +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRNVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A483DRY9_LACPN +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRNVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Geodermatophilus pulveris TaxID=1564159 RepID=A0A239BT43_9ACTN +--DVAARIADLATDFTGQLAVSAVDLTTGERV-EWQPDLLLPTASVIKESILIALLRAAE +AGTVDLADRVTLEASERVGGSGVLKLFEGGLPTVRDVATLMIAVSDNTATNMVLDLIGGP +EPVNRAMAELGLDSIRLHNAVDELIG-NDVRRLGEATVRDLCELGRLIATRKAFGEMVSA +TAEEVLATQQYLDQAMRYTLAAPLSVASKTGSFT-GTRVDAGIVRFAAGGGFCYAVANHE +AS--------------------- +>[subseq from] Uncharacterized protein n=1 Tax=candidate division WWE3 bacterium CG_4_10_14_0_2_um_filter_42_7 TaxID=1975073 RepID=A0A2M7TDH8_9BACT +---LKKAIEKEIKGANGKYGIVVKNLKTGESC-FANEHMKFEAASLYKLWVMATVFNQIQ +EGKLSKNEVLSREVEELNRDSEVAELTEGTILSVEDALAKMITISDNYAALLLAKRI-GL +SIVQTFLKDNLLEESIIG--EP-----------PITTAYDVALFFEKLYNGELANQENTK +LMLNLLKGQLL-NHKLPKYLSEEVTVAHKTGELGI-FSHDAGIVYGEKGD-YIIAVLSES +DN--RLAAEEQIAKISKSVYEYf +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000486D6F9 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMHTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Uncharacterized protein n=1 Tax=Achromobacter sp. TaxID=134375 RepID=A0A0M7JAD0_9BURK +-qHVDAALTPLLAATPARVSLSLRDLDGGVVL-ARHTDRVQPSASIIKVPILLALLEAVA +NGRYALEQPLALPAAERAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWNQRANLEATRLQRRMMDAAA-REAGRDNYTSAGDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVALAVLADG +FT--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. SB0666_bin_14 TaxID=2604857 RepID=A0A6B0ZXJ5_9SYNE +---LEERFQALAAAQDLLVGAYVAVLGDGRHA-SLNPDRATAAASAIKTPVLLLTLLARG +QGELRWDETLQLQPHLVGGGSGWMGAEPPGRFPLYMAAREMITVSDNTATNLLIERLGGM +EAVNRRFLALRLQGTRVNNWLPDLDGT------NTTTPRDLALTLAMAESDALLSQRDRD +RFRAIHGSSRP-NSLLPLGFLQGVRILNKTGDIGT-AYADAGMIELPDGRRAVAAFLVEG +TEYNSPRMRRLIQNMAAAT---- +>[subseq from] VEB family beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A3G6V737_PSEAI +------------------------------------------------------------ +-----FEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT +DSVQKFLNANHFSDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGPAATNDVGV----------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces chryseus TaxID=68186 RepID=UPI00110F7833 +-----ERIREVFAGAEGVLHAVAIDTEPGTQEvAVGADGPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAISVSDNSAADLLLARV-GL +DTVRLLAGELGLPGTRIVGGPRDVLEVLDPLRTNASTPREITRLLRLVWRDEAGPPEACA +HVRELMARQVF-RHRLVSGFPDEVIVAAKTGTLP-GLHMEAGVVRYPDGGRYAVSVFART +RGASRPAVDAAIGATARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Gordonia sp. 135 TaxID=2676309 RepID=UPI0012BB2A94 +--RIDRNVAEILADAGCSGWLHATTIGSPQISySYDADAPVVLASVYKLAVLISLCRSAD +RGEIDLTSPVTVDPTRWAQPTGLAALRDPITLSRRDLATSMMTVSDNVAADVLLDEI-GL +DRVREDLIGLGATSTRIVGGVAELHEAYDAAYTSSSTPRDCSTVLTAVWTDRAASAEMCA +FIRNTMRRQVF-TSRLASGFPRRVTVAGKTGTLV-AIRNEVGVVEFPGELPVAVAVFTRS +ARPALPQVDRAIGELARTVVT-- +>[subseq from] serine hydrolase n=1 Tax=Nocardia terpenica TaxID=455432 RepID=UPI0014285341 +---------EIFEQAGVQGWLHARCLDCGAEI-GDGADEPVVLSSVVKVLLVLELGRQIA +AGQVDPTDRLRATAAYRLGGPGTSGCRDDVEYSLRDAAYLALSLSDNTAADLLFERV-GL +DNVRSLARELGLTRTRIAGALRDLLLALDPRRTTASTPREMTRLLELIARDEAGPPATCT +WLRELMSLQLN-QHRLPSAFPSNVLVWGKTGTLP-GLRNEIGVVEFPNGARYAVAVFTKA +RVHRLPQADRAIGAAARTAIE-- +>[subseq from] Serine hydrolase n=1 Tax=Megasphaera sp. TaxID=2023260 RepID=A0A3C1CMZ7_9FIRM +----------------TDLSIYCRPLEQGTPV--VYHERVLPSASLIKLPIMSTLFRKEK +EGTVSFSEKLRITSP--VE-GGSYYKRGGTLATISELIFHMIVESDNTCTNVLIDRL-GM +DAVNEEIRRLGMTHTILQRKMMDFIAS-RDGRENMTTVSDMGRFFSLLSRGHAVDAARDQ +RMLDILSHQED-NCILPAQLPHTVRVDHKTGELD-GIYHDCGLIYAPSG-PFILCLMADG +VS--------------------- +>[subseq from] Uncharacterized protein n=2 Tax=Gordonia TaxID=2053 RepID=L7KUA8_9ACTN +---VDRDVTETLADAGCSGWIHATTIGSPRIGySFDADAPVVLASVYKLALLISLCRSAD +RGDIDLTSSVTVDPTQWAQPTGLAALRDPITLSRRDLATSMMTVSDNVAADVILDEI-GL +DRVREDLATLGVANTRIVGGVAELHQAYDAAYSSSSTPRDCTTLLSAVWTDHAASNEMCA +FIRDTMRRQVF-TSRLASGFPRRVTVAGKTGTLV-AIRNEIGVVEFPGELPVAVAVFTSS +ARPALPHVDRAIGEVARTVVT-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Woesebacteria bacterium RIFCSPHIGHO2_02_FULL_39_13 TaxID=1802505 RepID=A0A1F7Z314_9BACT +--KATVAFKSMTKELSGVYGLYVLRLDDGSNY-GVNENEIFQAASLIKLPVIFAMYKEAE +GGNIDLDNKYRLKRTDKVAGSGSLYQKSEGYITYREMVRLMGKQSDNTAFNILVKLL-GK +DKIESVIKELGMIQTSLDKNE--------------TTPEDVGIFFDRLYNGNLISDASTN +EILEDLTDTIY-EDWLVAGIPGVIRVAHKYGRELH-IVNDAGIILSD--KPFVLVIMSKG +IV--EKEADEIFPVITRAVYE-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium tunisiense TaxID=219748 RepID=UPI0003178386 +-----KEIKRYLESREGNYSFYFEDLKSGFIY-GFNENVKMPAAGCIKLPIAMALLKEVE +NGKVSLNDLISIGDEDKVSFFGIIHEFSEKQYTLKELLVAMLIQSDNTAACKIINIL-GM +DKVNSLINDMGLKSTKVNKYPSEVKL--SDNEENITTSYDLSQCFKLLHNNTALSKEHSR +LIIETLKRHQL-NTRIPFYFQREANTANKIGTLET-VENDTALLNFSKGD-FVYTVMSNN +LP-TNVYGITTIARSGKMMFD-- +>[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium varium TaxID=856 RepID=A0A3S4V8G7_FUSVA +---------NIKKYDNKKYGIIIKSLESEFFL-KVGNMEAYPAASLIKLPILYELFNNSK +---YNLDEKIEITLKDKVGGFGIIQYHNNVKLSLRDLAILMIILSDNTATNILIDIC-GM +DNINFTLKKLGLKDTKLRRKMMDLKSK-NMGLDNYTSPYDMIKLLEVLNK--------NE +EIISIMKKQLC-NNKISHFIEKKIDFAHKTGDLPQ-IEHDVGIFDIEDKK-IIVVVMTKN +FENR--DEIELNNKVGEFI---- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Candidatus Melainabacteria bacterium HGW-Melainabacteria-1 TaxID=2013813 RepID=A0A2N1UQR4_9BACT +---LASRFRTHLNRLSAEAGWAACNLRSGRSL--VFNDRRFLAASTIKLPLLLIYAQHRH +--QAIFKEPYIYDPQVYCEDSPCFDAVVPGTVSWDDIATWMMTLSDNTATNLLLDYF-GL +DAIQNWIQHQGFETMALNRRMMDLDAR-SRGIDNWTTPGEMMQLMARLANGSLMPAEASN +WSLEILHRCED-REKIPYFFQTPIRVANKPGELP-GIRCDVGYVHDEQHE-IVMAYS--- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. H6 TaxID=421122 RepID=A0A366CQH9_9MICO +---VERRIAEIFAEAGATGFLHAREIGGGPEV-TVGADEPVVLASVFKILVLTAFVRAVA +AGELDPAARTTVTARYRIGGVGTAGFADDVEMSWRDLALNMMTMSDNAATDVIYHRL-GA +EAIDRVISDLALRQTQLVGCCEDLFAAVQPLRTSHSTPREVTAVLNALWTDAAAAPEACR +QARDIMALQIW-PHRLTSGFPAEVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA +ASLN-DRQPLVDASIGRAAF--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sparsogenes DSM 40356 TaxID=1331668 RepID=A0A1R1S9E3_9ACTN +--SIEEKVAGVFEGAGARGWLHAIPVGGGREV-GVGADEPVVIASLFKILLVLEFARQSA +AGQLDPRERVLLTAADRLGGWGTAGCADDVEMSLRDLAFFALSVSDNTAADVLMRRV-GL +DTVRLLAAELGLDRTVVVGGPRELLEVLDPRRTTRSTARDVTRLLALIWRDEAGPPRACA +LVRELMARQVF-RHRLASGFPGDVGVAAKTGTLP-GLHIEAGVVHRPDGGCYAVAVFAET +RDTANPAVDAAIGRAARLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces albidochromogenes TaxID=329524 RepID=UPI00110F7266 +----EERIREVFAGAGAEGSLHAVPVGTEEEV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL +DTVRLLAGELGLAGTRIVGGPRDVLDVLDPLRTNASTPREITRLLRLVWRDEAGPPEACA +WVRDLMARQAF-RHRLVSGFPDEATVAAKTGTLP-GLHMEAGVVRYPDGGRYAVSVFART +RDASRPVVDAAIGATARIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis niigatensis TaxID=369932 RepID=A0A2N3WK24_9PSEU +----REQIEAVFADAGAEGFLHAREIGPGPEV-SAGGDAPVVLASVFKIPVALAYAREVA +AGRLDDTERTKVAARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVLCHRL-GQ +ETIDRVLADLGLARTRLIGCCEDLFAVRDPARTTSSTPREITALLDAIWTDRAGEPEACE +RVRTIMAQQIW-PHRLSSGFPSGVRVAAKTGTLP-GIRNEAGVVTLGDGRRFAVAVFTRA +HSDRLPAVDASIGAAARLAVDH- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis rifamycinica TaxID=287986 RepID=A0A066U0S4_9PSEU +-------------AVGVRGFLHARRLGSPAAV-GVDADAPVVLASVVKVPLAYEFARQVA +AGLLDPADRVRVTAADRLGGTGSAGFADDVSYSLRDAALLALSVSDNTAADLLFDRV-GV +DNVRSLLAELGLTRTTVIGAPRDVLRALDPQRTSATTPREMTTLLSAIWADDVGAP---- +-VREWMSAQVS-WHRLAAGFPPEVAVVGKTGTMP-GIRNEIGVATYPDGAAYAVAVFTAG +GAETRPDIDRAIGDAARAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI0009B8D930 +--TTDEQLRAVFADAGCRGWVRAERIDTGTTV-DYEGDDPVVAASVWKIVLLVAAARAFD +EGSLTATDSVRLVPAQCSPPTGIASYADPVTMSWRDIARSMITVSDNAAADALLGAV-GL +DALARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSIWLGTAASPTQCL +YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPDETPVAVSVFTRA +ARMDLPLVDQAIGHAARIAV--- +>[subseq from] Beta-lactamase n=1 Tax=Spirosoma radiotolerans TaxID=1379870 RepID=A0A0E3ZW44_9BACT +--TLERQLRAALTGFRGEAGIYVHNLRTGKTV-AINADTLFPTASTIKIPIQCGLFDKIH +KGELKYGNPIVYKDSLHYDDGIVGSLKDGAKIPLNEVVMLMETVSDNTGSLWCQALAGGG +STINAWLDANGFHQTRVNSRTPGREAHRTRYGWGQTTPREMADLMTYIRQGRAVSPDASE +EMYRNLGRQFW-DNDGLSQIPPEIKTACKNGAVNQ-SRSEVVFVHAPHGE-YVYCIMTKN +QKDETNEGFVLLRTVSAILWHHf +>[subseq from] Beta-lactamase n=2 Tax=Clostridium TaxID=1485 RepID=A0A174HJD8_9CLOT +-----KEIKKYLESRIGKYSFFFEDLKSGYVY-GYNENVPMIAAGCMKLPIAVSLIKAVE +DKKVDFMDKVKIQSGDKVYGTGIIHEFNEREYTVFELLVIMLIQSDNTAANKIIDIV-GM +EQINEDIIAMGLKNTRLNRKTNDERTA-ITDVENITTAYDLSRIWKHLANGTFLSKDNGQ +MLIDILRRQQI-KNKLALYIPDDIEISSKTGDKK-GVENDTAYLELPKGK-FTFTVLSQD +IPNS-VYGTVSLAKCGKMMWD-- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. S4605 TaxID=1420897 RepID=A0A317K8C5_9ACTN +--------------------------DGGREV-AVRADEQVVIASIFKILLVLEFARQVV +AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DVLPMLAAELGLSRTRIVGGPRQLAEVFDPERTTSSTAREITLLLGLIWRDEAGPAEACA +MVREWMSRQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARM +ADTRRIDVDLAMGEAARTAV--- +>[subseq from] Serine hydrolase n=1 Tax=Deinococcus irradiatisoli TaxID=2202254 RepID=A0A2Z3JBH5_9DEIO +--------------HPGEVGLYVCALDGTVLT-TLNAEQVFPAASTIKVPLLLLALERAQ +AGTLDLAERLTVHSGDRVGGAGVLHELGAGLPSLQDLLTLMIIVSDNTATNMVIERL-GV +EAVNAWLAAGGYEHTHLVGKLEQHNAAQRRGERNRTTAGEQVRLLLDLWRGAALDETHRA +LALSILGRQQY-RDILARRWPLDYAAHTKSGELV-GVHHDVGLLMLP--RPLCVALLSRG +GTDR------------------- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CFH S0261 TaxID=1644109 RepID=UPI00106FEAD1 +---ASETIARRAEEVGVEVRLHAAEVDGTRSL-GIGEDVPVVPASVFKVPIALELARQAA +EGTLDLGAPVTVEPGHPTPPYGLATFRHEVRMSWHDLAILMIGISDNVATDLILAEV-GK +DAVNSTLRRLGFTRTVVPQDCGELLAALQPEKSCRTTAAEMTRLLGLIWRDEAAAPEACA +DVRRWMELQVW-PHRLRSGFPDGIRTSGKTGTLP-AVRNEVGVVEYPDGGRYSVAVFTRA +EDSRVPERDAFIGFAAATAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Megasphaera hexanoica TaxID=1675036 RepID=A0A344MHM6_9FIRM +----------------TDLSIYCRPLEQGTPV--VYHERVLPSASLIKLPIMSTLFRKDK +EGTVSFSEKLRITSP--VE-GGSYYKRGGTLATISELIFHMIVESDNTCTNVLIDRL-GM +DAVNEEIRRLGMTHTILQRKMMDFIAS-RDGRENMTTVSDMGRFFSLLSRGHAVDAARDQ +RMLDILSHQED-NCILPAQLPHTVRVDHKTGELD-GIYHDCGLIYAPSG-PFILCLMADG +VS--------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=A0A349BXR0_9FIRM +------------------------------------------------------------ +--------------------------------TCADSLRYMITESDNSATNRIIDYV-GM +DNINRFIEKYGFTETKLQRHMLESSSR-----DNFSSARDAGICLAMIYDGTYVSEEASG +TMRNLLLQQER-RGKIPAGLPSGTKCGNKTGELNY-AENDAAIIWGPSCD-YVLVVFAGN +ISAP-GTAQSQIRHLSALVYE-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora eburnea TaxID=227316 RepID=UPI000B811F23 +------QVREVLERPGVSGCVHVVDVDDGREV-AVRADEQVVIASVFKILLVLEFARQVA +AGQLDPTERVLVRARDRLGGWGIAGCADDVEVSLRDLAYFAMSVSDNTAADLLLHRV-GP +DVLPMLAAELGLPRTRIVGGPRELVEVFDPRHTTSSTAREITRLLGLIWRDEAGPPVACA +AVRELMSRQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVYART +ERLSTRDVDLAMGAAART----- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora eburnea TaxID=227316 RepID=A0A1C6TVI6_9ACTN +------QVREVLERPGVSGCVHVVDVDDGREV-AVRADEQVVIASVFKILLVLEFARQVA +AGQLDPTERVLVRARDRLGGWGIAGCADDVEVSLRDLAYFAMSVSDNTAADLLLHRV-GP +DVLPMLAAELGLPRTRIVGGPRELVEVFDPRHTTSSTAREITRLLGLIWRDEAGPPVACA +AVRELMSRQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVYART +ERLSTRDVDLAMGAAART----- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0013634D67 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLYRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_40CM_4_68_4 TaxID=1805077 RepID=A0A1Q7HXW0_9CHLR +-------------SFPGGAAIVVQDGATGKILyQRDPDEEVITASLYKLGVLLEAERRVD +AGTLRYSDSITIEPEDVTEDGS--YESAGTTLTLDDALEQMITLSDNGAALALQRIF-GA +HEINATLAALKIEPFTLAEDPSE---------DNAASPRAIATFFTQLAQHTLVSKAASD +RMLQRLERQKI-NDRLPAQLPPGTIVAHKTGNLGF-VTHDAGIIYGKAGEPMVVVAMTWN +SSED--EAIDLIQSIGSLVYA-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535RPC6_9CHLR +--------DSRISSFSGGAGIVVQDGVTGKILyQHDPDEEVITASLYKLGVLLEAERRVD +AATLRYTDSITIEPEDVTEDGS--YESAGTTLTLDDALEQMITVSDNGAALALQRIL-GA +HEINTTLAALKIQPFTLAEDP---N------DDNVASPRAIATFFTLLAQRTLVSRAASD +RMLQRLERQEI-NDRLPAQLPPGTVVAHKTGNLGF-ATHDAGVIYGKAGDPVVVVAMTWD +SPED--EAIDLIQSIGSLVYA-- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. SB0676_bin_10 TaxID=2604869 RepID=A0A6B1F5K6_9SYNE +---LEARFQELAASQDLLAGAYVAVLEDGRHA-GLNPDRPMAAASAIKTPILLLTLLARS +QGDLRWDETLQLQPHLVGGGSGWMGFEPPGSFPLYMVAREMITVSDNTATNLLIERLGGM +EAVNRRFLALRLHGTRVNNWLPDLDGT------NTTTTRDLALTLAMAENSQLLSRQDRD +RFRAIHGSSRP-NSLLPLGFLQGVRILNKTGDIGT-AYADAGMIELPDGRRAVAAFLVEG +TEYNSPRMRRLIQNMAAATAK-- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium carnis TaxID=1530 RepID=A0A3P6K755_9CLOT +--SLEARIEAELISYAGKMCVYVNDF-KGNTI-EIGADEKFETASCIKSFILADLFSQVE +NGTKDLYEKLKYTKKNYINGSGVIQSLDEGVMTAINFAKLMIIVSDNVATNILIDYL-GI +DHINKTIQELGFKDTILHNKI-DFEK---YDKLGTTTPRDYGRLFELIAKKELISEEVSN +KMLDIFKMQHY-NSMIVRDFPQYIYVASKSGSMD-ACRNDGGLVFTPYG-PYVIVMFNKE +FHDSNHDATVYGGKVSRMIFDEf +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis lurida NRRL 2430 TaxID=1460371 RepID=A0A2P2FZ84_9PSEU +--DIRERIEAVFAAAGAEGSLHAREIGDGAEV-SVGADDQVVLASVFKIPIALAYAKEVV +AGRLDETEYTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWNRI-GQ +ETICRAVADLGLSRTRLIGSCEDSFRMCDPERETSSTPRETTELLDAIWTDRAGEPEACE +RVRTIMAQQIW-PHRLSSGFPSDVQIAAKTGTLP-GIRNEAGVLTLPEGRRFAVAVFTRA +HSLDLPEVDASIGAVARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. 02-925g TaxID=2022503 RepID=A0A260PSQ6_9NOCA +----TEHLRAVFADAGCRGWVRAERTDGTGTFvDFEGDDPVVAASVWKIVLLVATTRAFD +DGTLIPTDTVRLVPAQCSPPTGIASYADPVTMSWRDVARSMITVSDNAAADALLGAL-GM +DTLTRVIDDLGLEHTRIVGGTKALGDGFDPAYTSCTTPRDSNAVLRAIWSGTAASPEQCE +YMKHVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGEKPVAVSVYTRA +ARMDLPLVDQAIGAAARIAV--- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535K930_9CHLR +--DLIRQLDGLVASFPGGAGVWVSDPNVPTPLfTHDPDEQVIAASLYKLGVLAEAERRVD +AGQLHYSDEVVIQPEDITADGSFEE--AGTQLTLDEALEAMITISDNGAALALWHIL-GG +GNIDATLQKARITDFHVALDESE---------DHWATPRAVGTFFTLLAKRQLISPAASD +RMLARLERQQI-NNRLPAQLPAGVVVAHKTGNLV-GATHDAGIIYTKSGPRVVVAMTWDA +PD---EDADNFISSVGASVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Dehalococcoidia bacterium TaxID=2026734 RepID=A0A521X1J1_9CHLR +-eDLEKQFRAIGASTTGTWTAALTDLTTGEHI-AIDERRPMPPASLAKVPVLTALYQAVD +DGAVRLGDRVRYEEGHRSLGSGVLSMMSPGVMSVRDAAVLMMTISDNSATNMCIDLV-GL +DAINAKMRALGLTETQLMLRLGDPRIEMDARNMSLSSAGDIVRLLTLIARREAVLPESCD +DMLRIMRRCT-GRAELSKLLPRENWVAEKGGAMTNGVRCGGGIFRSPRG-FFALAVFAEG +GLNHESDANVFLGRMGKAAWD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Clostridium uliginosum TaxID=119641 RepID=A0A1I1KFS9_9CLOT +--------KRYLESRIGTYGFFFEDLNSGFSY-GYNENVQTVAAGCMKLPIAVSVIKAVE +KEKISFLDKVKIHQEDKVYGTGILHEFDDREYTIFELLVAMLIQSDNTAANKLIDIV-GM +DVINEDIKAQGLKNTHLNRKTSDERSA-SKGIENITSALDLSHIWKHLHEATFLSEKNST +MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKT-GVENDTALIQLSKGD-FVFTILSMA +IPNS-VYGTVTLAKSGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces lavendulae TaxID=1914 RepID=UPI00100853CF +-----QRIHNAFAQAGATGWLHAVDIDTGAEI-QAGADHPVVTASVHKLCLLLTLHQHAE +QGLLDLTEQLECPPAGRTSGPTGLAAMLDPVISLRDAAYLMTAVSDNAAAELLLGRV-GL +DAVNTTTRKLGLTRTRALHSFAQTLAALDPSRTNHSTPRDMTRLLTLIWRDESCTPEHGA +AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGTLPT-LRNEVGVIEYPDGGRYAIAVFTRA +ANATLPAIDAVIGTTARIAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Megasphaera micronuciformis F0359 TaxID=706434 RepID=E2ZAK6_9FIRM +------------------------------------EDVLMPAASLIKIAVMIEAFRRKK +EGTLDFSECLTVN--DVVEGGSFYIKRRDDSVPIYELIFHMITESDNTCTNMLIRSL-GV +ERINETVRSFGLVKTKLRRHMMDFEAA-RRGEENTTTMRETSELLSLLAQGRCVGPTEDR +AMIEILAAQED-NCLLPAQLPHNLTVAHKTGQLE-GLFHDCGIIYGRKK-PLICAIGARN +VTAE------------------- +>[subseq from] serine hydrolase n=1 Tax=Bacillus circulans TaxID=1397 RepID=UPI000BA53B0E +-eKLSKRIDKIVQEYEGHLGIAIEW--KEQSF-LLNENDIFPSASLIKLPVLIEGFMQSS +SGILDLEDLVKVNSLQKTGGAGIVQYMSPQSLSIRDLLTLMIIVSDNMATNYLIERL-GM +DNVNRRCQQIGMSSTILQRKMMDRE-ARERKIENYTSPQDILRCLKSIYNDKN------Q +SGKTILDHQQL-LDKLPYYHRSGIRIANKTGELDK-VEHDCAIIEYEDET-IFIAVLTDQ +LTAN-QKGKEIIQLIGASIFE-- +>[subseq from] serine hydrolase n=1 Tax=Oceanobacillus massiliensis TaxID=1465765 RepID=UPI00028A0C27 +--QLNSALLSMSAGMEGEVSIAIHT--DEGSI-GIDADVPRKAASVAKLFILGEAYRRLE +SNLLSFDKLVYIDHQSMVGGSGVISYLKNAHYSYQNLIELMIIVSDNTASNALLDAI-GM +EDINHFSKSIGCQHTIIERKFMDIEAA-EKGKDNITTANDVVCLLKLFSRNDYFPNKSRR +EILRILGDQQF-NNKLSTFNPPNIRFYRKTGELQ-GVEHDAAIIEANGK-RIEAAILTEG +WK-NNGTGQHYIAEVGQLIIDY- +>[subseq from] Beta-lactamase class A n=2 Tax=Tissierella praeacuta TaxID=43131 RepID=A0A1M4S797_9FIRM +--SLESRINAEVYNFSGKMGIYLNDF-KGNII-EINSDTKFETASTIKVFVLAELYRQIH +EKKINANKILKYEKENYVVGSGILRDLDYGVMTAKSFATLMIVISDNIATNILIDLL-GI +DNINNTCVDLGLKDTILHNKID-FEKY---SKLGTTTPRDYGKFFELLYKKELWSKEISE +EMIEIFKNQHY-NTILTRDLPQYVSIASKSGSMNE-CRNDGGIVYTPYGG-YVISLFTKD +FVDNDHESYRFGGKVSRLIFDQy +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI0009B86410 +--TTDEQLRAVFADAGCRGWVRAERIDTGTTV-DYEGDEPVVAASVWKIVLLVAAARAFD +EGSLTATDSVRLVPAQCSPPTGISSYADPVTMSWRDIARSMITVSDNAAADALLGAL-GL +ASLATVIEDLGLEQTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSIWLGTAASPTQCL +YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPDETPVAVSVFTRA +ARMDLPLVDQAIGHAARIAV--- +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC401 TaxID=1848324 RepID=A0A5R8NYV7_9ACTN +-------ARETLAAAGTTGAFHARPVGGGAEL-ALDADAAQVAASTYKIAVLLEVACQAA +DGELSLTRRVRVPGDVRSPPSGISTMLDEVELSVRDLALLMMQVSDNTATDVLQEIV-GT +ARLAARLDALGVRDTTVRLDCAGLIAALACATGNTTTARDMTTLLSLIWRDEAGPPEACE +EVRRVMLQQFA-PHRLSTAYRDGPKIAGKTGTFYGGVRNEVGVVDFGGGEEYAVAIFLRQ +HDLRDARADAAIGAVARLLVDH- +>[subseq from] Uncharacterized protein n=1 Tax=Rhodococcus sp. 15-649-2-2 TaxID=2023140 RepID=A0A260R1W5_9NOCA +--TTDEQLRAVFADAGCRGWVRAERIDTGTTV-DYEGDDPVVAASVWKIVLLVAAARAFD +EGSLTATDSVRLVPAQCSPPTGISSYADPVTMSWRDIARSMITVSDNAAADALLGAV-GL +DALARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSIWLGTAASPTQCL +YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPDETPVAVSVFTRA +ARMDLPLVDQAIGHAARIAV--- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. 34-1 TaxID=2709706 RepID=UPI0013D143DC +-eKLSKRIDKIVQEYEGHLGIAIEW--KEQSF-LLNENDIFPSASLIKLPVLIEGFMQSS +SGILDLEDLVKVNSLQKTGGAGIVQYMSPQSLSIRDLLTLMIIVSDNMATNYLIERL-GM +DNVNRRCQQIGMSSTILQRKMMDRE-ARERKIENYTSPQDILRCLKSIYNDKN------Q +SGKTILDHQQL-LDKLPYYHRNGIRIANKTGELDK-VEHDCAIIEHEDET-IFIAVLTDQ +LTAN-QKGKEIIQLIGASIFE-- +>[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. MYb62 TaxID=1848690 RepID=A0A2S9AKJ6_9MICO +--DTAADIAEIFADAGATGFLHAREIGGGPEV-GEGADEPVVLASVFKILVLTAYVRAVA +AGELDPTERTTVTARYRIGGVGTAGFADDVVISWRDLALNMMSMSDNAATDVIYHRL-GA +AAVDRVIADLGLRHTRLIGCCEDLFAAVQPVKTSHSTPRDVTTLLDALWTDTAAPAEACR +QSRDIMAQQIW-PHRLTSGFPAGVRLAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA +ASLA-DRQ--------------- +>[subseq from] Serine hydrolase n=1 Tax=Ruminiclostridium sp. MA18 TaxID=2488810 RepID=A0A4U7JN89_9FIRM +-dELEKLITDFTSKLPGKYGVTFIDLATGEMV-NVNDKIEYIAASTSKLPINVLLYKNIE +AGKIKMEDKLVYKKEDLEYGTGIIINSPYGTYTVRETSRLSIQKSDNCGVNMLIRLL-GI +ENVRNYIDEVGGQVHY--------------GKTHRSCPYDMAQIAQDLYKLYLNNEEVYG +ELINYMETTDW-SDRIDAKLPKDVKVAHKIGNQVS-TRNDVGIVFAT--HPYVLSIMSDN +VNVD--AATKAIADLSKLIYD-- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00040047D8 +--------DAHLDRMPGTVSAYLASLDATPTW-TRHPDTTHYAASTMKVAVLVALYRALE +AGRLAPDTAVPVRNEFDSARPGAAWDQLGGTASLRWLAERMIVRSSNLATNLLLDQV-GL +PAVADVWARAGARHSNTGRGIEDLAAR-AVGITNLVTTADLAALLRGLALGALATPESCT +AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCSTG +DHSPDEDACQLIADISARAF--- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Peptostreptococcaceae TaxID=200630 RepID=U2J1X9_9FIRM +--------------------------------------FQQEPASVMKIYLMAESMEQVK +EGRLSLEDTFVMDWNNMADDAGVIESSLGAEYRLKELQEYMMSISDNTASNMIIDAIGGL +EAVNKRKEEWGLENTVFGTKYIGPGVA-PGFDYNTTTTTDVGRLLKRIANFQLLGPEYDQ +KMLDLMAKNEN-WEKIPGLFPEEIKVYNKTGELD-ALEHDAAIIETPKGR-YVLVIFLSR +GD--------------------- +>[subseq from] serine hydrolase n=1 Tax=Clostridium cuniculi TaxID=2548455 RepID=UPI001054FB23 +-----KEIKKYLESRIGKYSFFFEDLKSGYVY-GYNENVSMTAAGCMKLPIAVSLIKAVE +DKKVDFMDKIKIQTSDKVYGTGIIHEFNEREYTVFELMVIMLIQSDNTAANKIIDIV-GM +EQINEDIIAVGLKNTRLNRKTNDERTD-ITDIENITTAYDLSKIWKHLSNGTFLSKDNGQ +MLIDILRRQQI-KNKLALYIPDDIEISSKTGDKK-GVENDTAYLELPKGK-FVFTVLSQD +IPNS-VYGTVSLAKCGKMMW--- +>[subseq from] serine hydrolase n=1 Tax=Sporosarcina sp. D27 TaxID=1382305 RepID=UPI00046FAFEF +--QLKEELDRIAYETTGDVSIYATT--PDGVI-AIRENEVKRSASILKVPVAMACLAAAD +RGEIDLDTLLKIEE--PVGGSGVLAYMSDMEITLRNALTLSIIVSDNSAANLVIEHV-GI +ERIQNFFKHVGATHSQLTRKFMDYD-ALAQGLENVATAKDMVRFLMCLDPSENLSQTSKQ +QLKTIMRDQQL-IDKLPAFQPETLIIGNKTGTLP-GVEHDIAYFENGER-CVNIAVLTTD +WEYN-HDGQQTLAQIGKAIIKY- +>[subseq from] Beta-lactamase class A n=1 Tax=Catellatospora citrea TaxID=53366 RepID=A0A419WY88_9ACTN +---ITNRIAAAFASADMQGWLHARDLDTGREV-AVGADDQVVIGSIFKILLVLEFARQTA +AGSLDPADRVLVRAGDRLGGWGTAGCADDVEMSLRDLAYFTMSVSDNTAADLLLRRI-GP +DLLPLLAQELGLTRTHLIGGPRELLAVFDPARTNSSTPEEVTRLLGLIWRDEAGSARACA +DVRALMFRQLF-WTRLAAAFPPGVRVAGKTGTLP-GLHMEAGVVEYPDGGRYAVAVFAKT +ERLSMPELDLVLGRAAKLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0014032DB0 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAVDKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Serine hydrolase n=1 Tax=Acidiferrobacteraceae bacterium TaxID=2024893 RepID=A0A2E7WRN8_9GAMM +---LENDLNQLCDEQPFHTGWYVRNLYTGDNL-QRHGDVVVPSASTRKIAIMMAALKAVS +EGGLALDQPVTMSAGYQDNDSGCFQHQPGFTIQLRDALVMMIIVSDNTCTGVVADLV-GL +ESINSLCQSIGMTGTVHRYGIPGMAGYLPAAQTNATTPADVAHLLDLILRGSGCRPESCQ +LAIDILSWQRL-RNRIPARLPLGTRVAHKTGTTAK-NYNDAGIVYFEDTPLFIISSYTDA +VEAE------------------- +>[subseq from] Serine hydrolase n=1 Tax=Plantibacter flavus TaxID=150123 RepID=A0A4U3G4M9_9MICO +---IAARIESVLEPLGVRGYVHAVDIDSGVEV-GLDADTDVVTASVFKLPVLVELARQYE +VGALDPRQRIRVGADERRTDGPTLSILLDDVLSLRDLSVLMMSVSDNRATDLITDLV-GL +DAVNATMRSFGLERTVVPVDCDALFRVSNPESNDRTTPREITTLLAAVWRDEVIGAAAAA +EVRRVLGLQAW-SHRLVAGFPSRVKVSGKTGTLFF-IRNEAGVVEYPDGGRYAVGVFLRE +SSLRHPDADRAIGTVARVAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Clostridium gasigenes TaxID=94869 RepID=A0A1H0MMD4_9CLOT +-----KEIKRYLESRIGTYGFFFEDLKSGFIY-GYNENVQMVAAGCMKLPISISLIKAVE +KGKVDFMDKIKINGEDKVYGTGIIHEFNEREYTVFELLVAMLIQSDNTATNKIIDIV-SI +KQINEDLKEMGLRNTILNRKTTDER-NNNSDIENITTASDLSKIWRHLYKASYLNKENSE +MLVDILTRQQI-KNKLALYIPDDYEISSKTGDKK-GVENDTALIRLSKGT-FTFSVLSTN +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000976924B +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLIDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIIQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Serine hydrolase n=1 Tax=delta proteobacterium ML8_F1 TaxID=1775671 RepID=A0A1V4M4B0_9DELT +--SLEARLRAEVVSFSGHASFYANDF-KGNVI-AVNAHEQFEAASAIKVFILAEFFRQVH +EGRLDRLRLLTYDKENFVTGSGLLRHLEPGTLSAENLARMMIIISDNIATNMLIDLL-GL +ENINRTIESLGFTSTTLHNKID-FDRY---ERLGTTTPRDYGVYFEKLREGLLIAPEISR +EMLDVFKKQQY-NRMLTKDFPQYIAVASKSGSMD-AARNDGGIVFTPYG-SYVIVIFTKH +FKDPDHESYIYGARASRLIFNQ- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9SGL1_9BACT +--SLRRELEQIRSHFPGDMSIYMKNLSTADEI-ALDSDKEYETFSVIKLAIAAELMHQVE +S--GKFSDRITTKATDERLASGALYADPGLNPTIKDLLTLMIIISDNEATDLLADKV-GR +AQVTAYMRSLGLANTAIQFSDLDWDRYDAGIFFGHSTTKETGRLLEMMASGKLVSKDASG +LVLSIMEKQQI-NDRFPRYLK-DVRIAHKTGDGQPFVANDAGIIWVNNQ-PIILVV---- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides xylanolyticus TaxID=384636 RepID=A0A2S6HN86_9BACE +--TLEKRIQAELMSYDGKMGIYLNDF-HGNVI-TMGQDEKYETASTIKTFILACLFDEVE +KGNKSLEELVEYKPEHVVDGSGVLAALEPGALRVKDAAVFMIIVSDNIATNMMIDYL-GL +ETINSCIQKLGCKDTILYNPIH-FDRY---RQLGTSTPNDYGSVFTRLVKGELISKKADG +AMLEILKKQHY-NSMITKDFPPVISVASKSGSMD-ACRNDGGIVFTPYG-PYVIVMFHKE +FSDAAHPATIFGARVSKMVLDQf +>[subseq from] serine hydrolase n=1 Tax=unclassified Rhodococcus TaxID=192944 RepID=UPI000B9A6B00 +--TTDEQLRAVFADAGCRGWVRAERIDGPGTVvDYEGDDPVVAASVWKIVLLVATARAFD +EGSLTATDSVRLVPAQCSPPTGIASFADPVSMSWRDIARSMITVSDNAAADALLGAV-GL +DAVARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSVWLGTAASPAQCR +YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA +ARMDLPLVDQAIGHAARIAV--- +>[subseq from] serine hydrolase n=1 Tax=Nocardia brasiliensis TaxID=37326 RepID=UPI0004A743FB +--------REIFRKAGVRGWVHARCFGCAGEH-GLEADEPVVLASVVKVPLVLEFARQVA +AGQLDPADRVRVRAADRLGGVGTAGCFDDVELSLRDAAFFALTLSDNTAADLLFDRV-GL +DNVRSLVRELGLTGTRIVGAPRDIVQALDPRRTTASTPREMTRLLTLIGQDLAGPAQACG +WVRDVMREQVN-WYRLAAAFPPEAQIWAKTGTLP-GVRNEIGVIEYPDGSRYAVAVFTRT +ESQRLPEVDRAIGAAAVAAID-- +>[subseq from] Uncharacterized protein n=3 Tax=Candidatus Gottesmanbacteria TaxID=1752720 RepID=A0A2M7RP97_9BACT +----LPRIEKEIGGLGGTFSVYLYDINNNVEI-GLDENMVLTAASVNKIPILAALYNLAG +KGEIDLEKVIVIQPGDVQDTGSIRYDPPRSSYSIKTLARLMMEKSDNTAAYILGSHIVGL +KKIQNLVNSWDLTQTDMV--------------ENKSSVKDMSILMIKMYHGEITTPPLTT +EMMGFMDKSDF-DDRIPAGLPENVKFYHKTGDEI-GKIHDAGIIDLKNR-PYFLGVFTTD +MK-DEVKTKKAIANISKIVFEY- +>[subseq from] Uncharacterized protein n=1 Tax=Actinobacteria bacterium 69-20 TaxID=1895696 RepID=A0A1Q3PVN5_9ACTN +----ATAIAAASADAGADVFAHAIDIDSGAGV-GVRADDPVVTASVFKVPVLTEYVRQVS +AGDLDPASRVLIRSGSATMGPTGLSVFSDDAWSLRDVATSMITVSDNAATDIVTGMV-GV +DRVNATMAELGLPGTVLIGDCRVLFDVCTPTLTNRSTPRECARLLQLLWTDRAADPAGCA +EARRILGLQVW-PHRLSSGFPDDVRISGKTGTIGI-VRNEIGVVEFPDGHRYAVAVFTRS +HRYRQPKVDALIGTVAAALV--- +>[subseq from] Beta-lactamase class A-like protein n=2 Tax=Candidatus Woesebacteria TaxID=1752722 RepID=A0A0G0M1W6_9BACT +-eKIQKEFKEKTGNLSGVYGLFVIHLDNGFSY-GVNENEIFTAASLIKLPVIAGMYMEDE +AGNIDLDEKYTLKNSDKVTGAGSLYGKPAGYTTYRNLVQLMGKQSDNTAFNICRKLL-GD +EKIDEVTRSVGMVDTSLEK--------------NETTPKDIGIFFEGLWRGNIVSQESRD +EILDYLTDTIY-EDWLPAGIPDDLRIAHKYGREVH-VVNDAGIVFTT--KPFIVVILTKG +VI--EKEADTVLPELSEIIYE-- +>[subseq from] Beta-lactamase n=1 Tax=Haladaptatus paucihalophilus DX253 TaxID=797209 RepID=E7QPE7_9EURY +-dELAATIAAYDETIDGDLGVFLGFPSGPDVVcSHDETRVFQSASTVKLPVFYALYERYD +ADDDELDRPCPLSPENRVGGSGLLHL-LNATPTVEDLARAMISVSDNAATNQLIDHL-GM +SAVNDAAARLGMDRTRLARKMMTTLEVPADEPTNATTPLDCARFFADLACETTLSAAAYE +RMRVPLAAQKD-TSMVPRYLPYETDVAHKTGRLPT-AALDTGFLSVPDRRPLVFSVFIDG +VGGTETDGARATSDTGAD----- +>[subseq from] Serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A0X8P1S8_ALCXX +--YVEAALAPLLAATPARVSLSLRDLDGGIVL-ARHADRQRPSASIIKIPILLALLEAVA +GGRYALEQPLVLPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIELL-GF +DEINQWSQRVGLTASPLQRRMMDAAA-REAGRDNFTSADDATAALCWLLRDGALPAPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. GP55 TaxID=1798190 RepID=A0A2N3UEF3_9ACTN +--SARTRIAEAFAEAGVTGLLHARDLDAGTEL-ALGADTLVSTASVHKLCVLTTLFRHAG +AGRIDLTRRLDIPAFGRTDPTGLAAMLDAARLSLRDLAYLSIAVSDNTAADLLWDEL-GL +DAVNGTMADLGLTRTVAVHKIRDMIAVLDPAFTNRSTAREMTALLAAIWHDRACPGEHGA +ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVIEYPDGGRYAVAVFTRA +TATSLPAADAVIGTAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Clostridioides difficile TaxID=1496 RepID=UPI0009432A97 +-------IINKLKNMKGDVSFYYKNLVTQEII-KYNEEKPMLAASVIKLTVLVECFNQIK +KYIIRKDDIFITKEEDKVPSCGALNYMRENLITLEDLYVLMIILSDNYATNILIDKL-GI +DNINKTIKEIGLKNTVLNRKMFDSDKA-ALGLENYISAGDIAYLLEKMYNKELIDEKSSE +EMINILKNQRL-NGKVPQSIKPKVNIAHKTGEDTN-ITHDVGIVFD--KEPFIVCFCGNN +V--NVPEYERLMQDVT------- +>[subseq from] serine hydrolase n=1 Tax=Catellatospora methionotrophica TaxID=121620 RepID=UPI001408ABFD +---ITNRIADAFAAADMRGWLHARDLDTGREV-AVGADDQVVIGSIFKILLVLEFARQAA +AGSLDPADRVLVRAGDRLGGWGTAGCADDVEMSLRDLAYFTMSVSDNTAADLLLQRV-GP +DLLPLLAQELGLTRTRLIGGPRELLAVFDPARTNSSTPEEVTRLLGLIWRDAAGPAQACA +DVRALMFRQLF-WTRLAAAFPPGVRVAGKTGTLP-GLHMEAGVVEYPDGGRYAVAVFART +ERLSMPELDLVLGRAAKLAV--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces chryseus TaxID=68186 RepID=UPI00110F902E +-----ERIREVFAGAEGVLHAVAVDTEPGTQEvAVGADGPVVIASVFKVLLVLEFARQVT +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAISVSDNSAADLLLARV-GL +DTVRLLAGELGLPGTRIVGGPRDVLEVLDPLRTNASTPREITRLLRLVWRDEAGPPEACA +HVRELMARQVF-RHRLVSGFPDEVMVAAKTGTLP-GLHMEAGVVRYPDGGRYAVSVFART +RGASRPAVDAAIGATARIAVD-- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Brevibacterium casei TaxID=33889 RepID=A0A449DBT8_9MICO +-----DEINGVWTSLGAQGFLFAEDLETHRSV-GIRESARIPLASVGKVAIVAGLLDAAA +DGVLDLTRRVVVDPTTATPGTGISGLHDPVEMSLRDLAAMALSVSDNAAADTLFALV-GP +ERITALLHRFGIRSFDVVAPMSHLYDQLPDSAFNTGTVRATARLFELIHTGRLLGAEDSA +VLRDLLRRQIF-RHRIAAGFPDAVSYYGKTGTFLN-FRHEAGVIVDSDGAAYSIAIFTRS +TIATQPELDASIGYCARLAIEH- +>[subseq from] serine hydrolase n=1 Tax=Jiangella alba TaxID=561176 RepID=UPI0009F39667 +---------------GVTGFLHAADVGSGAEV-GVEPDAPVVTASVFKIPVLVELCRQFA +TGERAPADRLRVPAGGRTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR +EKINAGTAALGLTGTVLEEDCAGLFRVLDARTTNRSTPRETTTLLRRVWTADGLPAAACD +EIRRILALQVW-PHRLTSGFPDDVRVSGKTGTLSH-VRNEVGVVEYPDGGTYAVAVFLRL +PGAENPAADAVIGTAARIAVDH- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000E59F39F +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNKAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces auratus AGR0001 TaxID=1160718 RepID=J2K8Z7_9ACTN +---TQDHIRTAFADAAVTGWLHACDIDTGAEV-GFHPDHPVVTASVHKLCLLVALHQCAA +QGDFELTEQIEVPPTGRTFGLTGLGAMLDPAVSLRDAAYLMMSVSDNIAADLLLERV-GL +DAVNRTTTQLGLSHTLAIHTFQQLLDALDPARTNRSTPRDMTRLLSCIWRDEAGTPDHGA +AIRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA +ANATLPAADAVIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis regifaucium TaxID=546365 RepID=A0A154MP61_9PSEU +---VVETINDRAEEVGVRVRLHAAEIDGTRRI-GIDADTPVVTASVFKVPVALELARQAA +EGELDLGERITVVPGHPTPPYGLATFRHEVTMSWHDLAILMIGISDNVATDLILDRV-GP +EATGETLRRLGFEHTIVSQDCGEILGALQPAHTCATTAEEITRLLTLIWRDEAASPAACA +DVRRWLELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAARA---- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=UPI000C1259F6 +------------------------------------------------------------ +------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM +TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS +KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ +VQNPAAERQA-IGA--------- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0013748BB3 +----TDLVAQATNGLAGQTSLAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6SLA9_9BACT +-------------------------------------HRRFKAASVVKIPLMIEVYRRVE +RGELRLDERHVLAARDKAAGSGVLLHHPGLTLTIEDLVYLTMSISDNSATNILIRRV-GM +DRVNATMQGLGMTESTLGREMKGRV-AEPGEAENWATPGDYVRAVRAILDGEAAGPAGCA +AMVAMLERQQN-PRRIGRYVPEGVRWGSKTGGLK-GVTNAV------------------- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Euryarchaeota archaeon RBG_13_61_15 TaxID=1797978 RepID=A0A1F9ZKR9_9EURY +---LRADIIKAAKEVKGQMGLYLKHVESGSEV-AIDADKTYPLASVFKLAVMVETYRQVE +DGLISLDERIELEPRHYCIGEGVLQYLSPGLPTVQDLLALMILETDNTASEMLWKRI-GI +QRVGMLMKELGLAKMSI------------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces luteus TaxID=1915400 RepID=A0A086N748_9ACTN +---------------------AAGEWTAADEV-AVGADEPVVIASVFKVLLVLEFARQVT +AGQLDPRARVRVTAADRLGGWGTAGCADDVELSLRDLALFAISVSDNSAADLLLAQV-GL +DTVRLLAEELRLERTRIVGGPRDVLQVLDPSRTNASTPREITRLLCLIWRDEAGPPQACA +QVRDLMSRQVF-RHRLVSGFPDEATVAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART +REASRTAVDAAIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Halobellus captivus TaxID=2592614 RepID=UPI000EFC3526 +--DLAGAIDSIADRFDGRLGVFLGVPRGADAFhRRNADEEFVSASVIKLPILYALYEEYD +GRLERLAETRPIAPENRVGGSGLFHLLDRPTPSLEDLARAMIAISDNAATNELIDAL-GA +ERIESAATRLGMTNTRLRRKMMATLGLPDNGPANVTTPTDCARFFADLVHEATLSPAAYA +RLRVPLDEQKD-RSLFARFLPYRTPIAHKTGGLPT-AAIDVGVLRPADVSPLVFSAFATR +AGNG-GDASDAVAAVGEAAFE-- +>[subseq from] Uncharacterized protein n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=A0A349BYU1_9FIRM +------------------------------------------------------------ +-----------------------------------NTVRNMIVYSDNEACNKLIDLV-GM +KNINQFIQNKGFSKTRLNRKMLA------KGEENYTSAKDCARLLQAVLNGKFVSSGASA +SILKYLKAQTR-TGKIPAGVPSGVKTANKTGELAY-TENDAAIVWGKKG-PYIIVILSDQ +VGAPG-KARTAITNMSRITYD-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000932E8E9 +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTLVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Desulfofundulus thermosubterraneus DSM 16057 TaxID=1121432 RepID=A0A1M6G769_9FIRM +---LQNQLKDYLAQQPGVYGIYFKDLHSGASF-DINGDEPITAASTVKVPVVLYLNHLVA +QGRLEWDDRVVYDSKDYQGGAGILQFSARDGYSLRILANLSITISDNIAYRMLVRHL-GK +DNVAQFMRDLGGQTV------------FPG-GENITTARDMGRYMEAVLEFSRKHPALGE +RLLDDMANPIY-HVGLPGRLPPEVRVAHKEGDVW-GVANDAGIVFAE--HPYILVVLSKG +ET-DVDKGFARIAEISRMVYDY- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces europaeiscabiei TaxID=146819 RepID=UPI00067CB6BE +-----------------------------GEV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDLRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL +DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA +RVRELMARQAF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART +REASRTAVDAAIGATARIAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. OF04-11AC TaxID=2293109 RepID=A0A373NWG9_9FIRM +--TLEKRIAAELYSYQGKMSVFVDDL-QGHTV-EMGADEEFETASTIKAYILAVLYLQAS +RGKASLTEEIEYRPEHFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMVIDYL-GL +ETINACIKELGFAHTVLHNPLH-FDR---YEKLGTTTPRDYASLFAQVAKGTLVSAEASA +EMLAIFRQQHY-NTMLTHDFPERIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKD +FH--------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis rubida TaxID=112413 RepID=A0A1I5JD50_9PSEU +----RARIEAVFADAGAEGFLHAREIGPGPEV-SAGGDAPVVLASVFKIPVALAYAREVA +AGRLDDTERTKVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVLYHRL-GQ +EKVDRVLADLELARTRLIGCCEDLFAVRDPERTTSSTPREITELLDAIWTDRAGEPQACE +RVRTIMAQQIW-PHRLSSGFPPGVAVAAKTGTLP-GIRNEAGVVTLGDGRRFAVAVFTRA +QSDRLPAVDASIGAAARLALDH- +>[subseq from] Uncharacterized protein n=1 Tax=Armatimonadetes bacterium TaxID=2033014 RepID=A0A3D1I8U3_9BACT +-qALAEELNAHAERLRGTAGFWVEELRGARSA-GRLADRPFPTASTIKTALMVAVLREVE +AGRMAWTETLPVPPPDRRELSPWSWFFPEGQIDVDGWVNLMIGYSDNTATIVLRDRV-GT +ETINRMLEELGFRHTRFLSGTPPLAELRATFGLGVTTPREMARLLKGIALGHWAGPAASE +RMVRILSHQYW-DNLIASAVPPCVLCASKSGFVAS-SRSDTAIVFGP--TPYVAAFYTSD +LCGPNNEAVRWIREASGIVW--- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003682755 +----------HLDRMPGTVSAYLARLDAAPTW-TRHPDTTHYAASTMKVAVLVALYRDLA +AGRLTPDTAVPVRNEFDSARPGAAWDRLGGTAPLRWLAERMIVRSSNLATNLLLNQV-GL +PAVADVWARAGARHSVTGRGIEDFAAR-AAGITNLVTAADLATLLRGLALGALATPESCA +AMLDLLVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCSTD +DRSPDEVACQLLADISARAFA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis tolypomycina TaxID=208445 RepID=A0A1H5A6T0_9PSEU +-------LAAFFEAVGVRGFLHARRLGSAESL-GCDADAPVVLASVVKVPLAFEFARQVA +AGLLDPTDRVHASAADRLGGTGSAGFADDVSYSLRDAALLALSVSDNTAADLLFDRV-GV +DNVRSLLAELGLTRTSVIGAPRDVLRALDPLRTSATTPREMTALLAALWADEAG-----A +PVREWMTAQVS-WHRLTAGFPPEVAVAGKTGTMP-GIRNEIGVARYPDGAEYAVAVFTVG +GAETRPDIDRAIGQAARAAVDQ- +>[subseq from] Uncharacterized protein n=2 Tax=Firmicutes TaxID=1239 RepID=A0A1C5NRB9_9FIRM +--------------DKAAVSLYCRPLDGGDDF--FYRDRVMPSASLIKVPIMACVFRQEK +EGQLSFDAAYPVYGN--VEGGSFYDLPEGTEVSLRTLVFHMIVESDNTCTNMLIDVL-GF +DAVNEEIRRQGMEHTLLRRKMMDFEAA-RQGKENVTSPGDMGRLFLRLASGTCVDGRRDE +AMRAILAQQED-NCILPAQIPNTVAVEHKTGELD-GIYHDCGLVWKQGR-PYVCCLMADG +IV--------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Rhodococcus sp. 06-412-2C TaxID=2022487 RepID=A0A260AB43_9NOCA +--TTDEQLRAVFADAGCRGWVRAEWIDTGTAV-DYEGDDPVVAASVWKIVLLVAAARAFD +EGSLTATDSVRLVPAQCSPPTGISSYADPVTMSWRDIARSMITVSDNAAADALLGAV-GL +DALARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSIWLGTAASPAQCR +YMKGVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA +ARMDLPLVDQAIGHAARIAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium RIFCSPLOWO2_01_FULL_39_10 TaxID=1798622 RepID=A0A1F6KLB2_9BACT +---LKHIVESNFSKEKGEWAVVVKNLKTGESF-KYNGNQKFDSASLYKLWVMAVAKGQIE +NGNLNEGTLLSAEKEKLDELSTVTEEFKKEIMTVSDALEKMITISDNYSALLLSARV-GP +SNITSFLKDYGFDNSNYAS---------PP----ETSASDIAEFFELLYKGEIVSEKTSI +EMIEILKQQTF-DDRIPKYLPKNTEVAHKTGELF-GAKHDAGIVFSKGGD-YIIVVLSKT +EN--EKEAAEKIARFSEEIYKYf +>[subseq from] Uncharacterized protein n=1 Tax=Clostridium sp. 27_14 TaxID=1896979 RepID=A0A1Q6LFN8_9CLOT +------------------------------------------------------------ +-------------------------------------IKLMITQSENFATNRMIDRL-GF +DKINNYIRSNGYTNTELNRYMLKSNAN----GDNYTSSKDAAKILENIYNHKCVSYEASE +QMMAYLKAQQL-RSKIPDGVPSGVQTANKTGELDT-VENDAAIVFKDN-APYVLVVMSSG +LSD-TAKARQNIVDISKIVY--- +>[subseq from] serine hydrolase n=1 Tax=Rubrobacter sp. SCSIO 52909 TaxID=2653851 RepID=UPI00140991B7 +--DLHQKLKRIADAYPGRYGVVVSDPSTGQTV-SMDPDGRFLAASLNKLPVLMTLYRSAA +AGTVDLDDEISMQASDVQAGTGSLYKPIGYTLTLRECAAFLIKESDNTAWKMLDRYL-GR +DYIRSELQRVGASTTE--YWIP-----------NTTTPNEILIMLEKIADPSYTSPELSA +EMLDLMKNTDF-EDRLPQPLPKGAEVSHKIGSYG-ATFGDAGLVFPKGSDAYFIVVMVDE +TGE--GTARAAMQEMSLASYKTf +>[subseq from] serine hydrolase n=1 Tax=Clostridium beijerinckii TaxID=1520 RepID=UPI0004799558 +------EIKRYLESRIGTYSFFFEDLESGFSY-GYNENVQMTSAGCMKLPIAVSIIKHVQ +EGNSTFLDKIKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIDIV-GI +DKINDDIEAQGLKNTRLNRKTSD-ERAVSNGIENITSALDLSKIWKHLYNSNFLDEKNSK +MLMDILQRQQM-KNKLALYIPDDYEISSKTGDKAS-VENDTALIHSPKG-SFTFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces viridosporus TaxID=67581 RepID=UPI0009BDF46C +-----------------------------REV-AVGADDPVVIASIFKVLLVLEFARQVV +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNTAADLLLARV-GP +DTVRLLAKELGLERTRIVGGPRDLLEVLDPRHTTASTPREITRLLRLVWSDAAGPPEACA +FVRDLMSRQVF-RHRLASGFPDDVAVAAKTGTLP-GLHMEAGVARYPDGACYAIAVFART +RDVSRAMVDAAIGRAA------- +>[subseq from] serine hydrolase n=1 Tax=Acidobacteriaceae bacterium KBS 89 TaxID=1267534 RepID=UPI0004BC8FBA +---LPAQIHAIEAEHHGDVALFAENLKTHETV-ATSPDTPVQTASVIKLAILYEALEQVR +SGKAHFDDRVTLTPADQVPGSGVLRLFDAPLLTLKDVLTMMVVMSDNSATNLAIDHL-GL +ENIDDRIAKLGLKDTYLYKKIFTPAPAMPTDQKGKTTAREMATLMTKFVRCELAEPASPT +QSEDAMLRLQFYRSAIPRYLDASDSIANKTGSLD-AVRNDVAAISTKNGIVIISAFTFNN +KDHSEQEGELTIAKLAKAIIQSw +>[subseq from] serine hydrolase n=1 Tax=Streptomyces melanosporofaciens TaxID=67327 RepID=UPI000B8536C7 +---IEKRIAEVFAEADAEGRLHAVDIDPGREI-GLGVDDQVVIASVFKILLVLEFARQAD +AGQLDPRERVVITAPGRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALVRRI-GL +DTVRLLAAELGLDRTRIVGGPRELLEVLDPRHTTSSTPRDITTLLGLIWRDRAGSPAACA +LVRELMSRQVF-RQRLASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART +ASAARTAVDAAIGRAARLA---- +>[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora alkaliphila TaxID=1783498 RepID=UPI0013B8C87C +---------------------------PGREI-GLLPDDPVVLASVFKLPLAVAFARAVD +DGRLDPTEPVTLSPDTRTPGATGFAAMSDPVISWRDAVRSMMTVSDNAAADALLDAL-GT +DDVNSTLAELGLTSTRVSGGTRHLYADPHLTTSTVGTCRDMTALLESVWHDRAASAEQCA +FIREVMAQQVW-TQRLAAAFPDDVVVAGKTGTFL-ALRHEVGVVEYPNGEAYAVAVFTLS +TRARLPGADAAIAQAAKLAV--- +>[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora sp. XMNu-373 TaxID=2650750 RepID=UPI001391D0E1 +--------AKIERSFGVFGCLHATDLHDSREV-SFQADEQVVLASVFKLPLAVAFARMVD +AGEIDPLATTTFDPAQRTPGSTGIAAMTDPVLSWRDAVRSMMTVSDNAAADALFDLV-GA +SRISAMLADIGLTATRVVGGTRDLYADAGRAANNVGTCLDMTKLLEAVWQDRAASSEQCA +FLRSVMAQQVW-TQRLAAAFPDDVVVSGKTGTFV-ALRHECGVVEYPNGEAYAIAVFTLS +TRGRLPSADASIAHAAKLAVA-- +>[subseq from] Serine hydrolase n=1 Tax=Dethiosulfovibrio peptidovorans TaxID=47055 RepID=A0A2G6M2X1_9BACT +-----------FEAFGATAGLVVSVHGSNFRW-SHNDSRVFPSASLIKLAVLWSLFKGSD +RGLWSLEDEIDILGDQIVEGGLLHRRAPGGSLRLDDIALLMIAVSDNTAANLLIDHI-GL +ERINEDIGLLGLKETVIGRKMMDFESK-KIGKDNYTSPRDMEKLIRSLTLEDMFPLR--E +RALDMLSCQKL-NSKLAGEIPLEGFLAHKTGELP-GSEHDCGVFFHKENNPIIVTVLTEG +LANP-CLGIELCRDVGRVVYNTf +>[subseq from] Serine hydrolase n=1 Tax=Pseudonocardia sp. MH-G8 TaxID=1854588 RepID=A0A263DU19_9PSEU +----AERVRAVLEAADADGAVHVRRIGGPQRF-ALAADRPVPSASVFKILVLLEFACQVA +AGTLSPTTRIRVPADERTMPTGLSVLRDDVEMSARDLAVLMMQISDNTATDVVQRLV-GT +ASVARRVAALGLTATVVEHDCRDLLASLRAECGNRTTAREMTALLELIWRDEAGPAQACA +ETRRVMGLQHA-PHRLSTAYADGPVISGKTGTLV-GVRNEVGVIDFGAGEQYAVAVFLRG +RTQRDPAVDRAIGQVARIVVD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces antimycoticus TaxID=68175 RepID=UPI001374D0B8 +---IEKRIAEVFAAADAEGRLHAVDIDPGRQL-GLGVDDQVVIASVFKILLVLEFARQAG +AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL +DTVRLLAAELGLDRTRIVGGPRELLEVLDPRHTTSSTPRDITTLLGLIWRDRAGPPAACA +LVRELMSRQVF-RQRLASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART +ASAARTAVDAAIGRAARLAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Cnuella takakiae TaxID=1302690 RepID=A0A1M5F893_9BACT +------KIVALAQGFNGSIGIYVKDLRSGKTV-SLNADTIFPTASIVKIPLAVGIMDKIG +KGELSYHQELVYNDTILYPGVDILGSYKNGEVELSKVLMLMLTTSDNTASLWLQQMAGTG +TRVNTLMDSLGFPELKVNSRTPGREATRAVYGWGQMTPRAMASLLENIYRRQLLSQAASD +RLLRSLNRNYW-DGEALSQIPPYAALFSKNGAVD-ASRSEVVLVRGRKS-EYLFCIATKN +NKERGNEAWVLTRKLSAMLWDHf +>[subseq from] serine hydrolase n=1 Tax=Agromyces sp. HY050 TaxID=2651191 RepID=UPI0012ECF15F +-qALRERIGSIEAELGVTATMHAIDIDTGEEF-GVAADDLVVPASIFKVPVLTELCCRFA +DGSIDPAQGMFIAREAFRTGDTGLSVFLDDVLSVRDLAVSMMSVSDNRATDILIDLL-GL +DAINERSRRLGLEQTVLVEDCAGLFRVLDASATNRTTPREVTASLALLWDGGVLAPAATA +EARRILSLQVW-PHRLKAGFPSRIRISGKTGTLPY-LRNEAGMIEYPDGGRYAVAVFVRE +TLEENIDADRSIGLIGRAVVDE- +>[subseq from] serine hydrolase n=1 Tax=Acidisarcina polymorpha TaxID=2211140 RepID=UPI00123822C8 +------------------------------------------MQSAFKFLLNVAVLHAVG +QGKLSLEQSVHSLPSDTYKFSPLQDMYPAANVPLRQLPELWVGHPDNTANDILLRQMGGT +APVQQYLDSLGLQGIQIRDSEASMHDDERRQYRNTGEPATFVKLLCMLAENSLLTHGNTK +YLLSIMSSSPSFPNRICGLLPAGTIVAYKTGTAGYNATNDVALITLPTG----------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Bacillus hwajinpoensis TaxID=208199 RepID=A0A4U1MLZ0_9BACI +--QVSERILDCFRSLEGNQSLYVLAP--DGEI-ALNEDQPVSSASIIKLAIMIAALRKVD +NGELNFNTVIPIESSNKVEGAGVISFLSNDLWTVSDLIKLMIVSSDNTATNQLIELL-GK +DEINHTMKCAGAFHSKLMRKMMDWEA-VKDGRDNMISSKDIYLLLNELVTEHLLSKSSME +WGITVLMQQQL-KDKFPAKIAQNNVLAHKTGELP-GLEHDSGILFTSKG-PVIYAFLTAG +LI-ENRYGRDAISNAGRLLYDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora rhizosphaerae TaxID=568872 RepID=A0A1C6RTH7_9ACTN +---AEEEVTEIFSRAGVTASLHVMAVEPGREV-AVRADEQVVIASVFKILLVLEFARQVA +AGQLDPVERVLVRAEDRLGGWGTAGCSDDAELSLRDLAYFAMSVSDNTAADLLLRRV-GA +DVLPMLAAELELPRTRIVGGPRQLVEVFDPAHTTSSTAREMTRLLGLIWRDEAGPPAACA +MVRELMGRQLF-WTRLPSGFPPGVHVAAKTGTLP-GLHLEAGVAEYPDGGRYAMAVFART +ERLSRIEVDLAMGEAARAAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V2RQ23_9BACT +------------------------------------------TMSVIKIPILVESFQQIQ +DGKFKLDDRLEWNDPKRRWGTGLLQILDSGMPTIRDYMTLMITLSDNSATDVMLEKIGGP +AAVDASMKKLGLKTIHCPGTAYDWFLSEEKNPFGLASPRDIGKLLEMIVKGEAVSADASK +KMIEIMRNQFY-MSRIPHYLPDPWSVPHKTGDFPPYLANDVGILEPGKQ-RVVIVVFNSH +FQGQYPLLEDAVAKIALEAYRFy +>[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A3D1RW74_9GAMM +---LENDLNQLCDEQPFHTGWYVRNLYTGDNL-QRHGDVVVPSASTRKIAIMMAALKAVS +EGGLALDQPVTMSAGYQDNDSGCFQHQPGFTIQLRDALVMMIIVSDNTCTGVVADLI-GL +ESINTLCQSIGMTGTVHRYGIPGMAGYLPAAQTNATTPADVAHLLDLILRGSGCRPESCQ +LAIDILSWQRL-RNRIPARLPLGTRVAHKTGTTAK-NYNDAGIVYFEDTPLFIISSYTDA +VEAE------------------- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 04169 TaxID=2203197 RepID=A0A429CVH5_9PSEU +--DIRERIEAVFAAAGAEGSLHAREIGDGAEV-SVGADDQVVLASVFKIPIALAYAREVV +AGRLDETEYTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWNRI-GQ +ETICRVVADLGLTRTRMIGSCEDSFRMCDPERETSSTPRETTELLDAIWTDRAGEPEACE +RVRAIMAHQIW-PHRLSTGFPSGVRIAAKTGTLP-GIRNEAGVVTLPEGRRFAVAVFTRA +HSDRLPEVDASIGAAARLALDH- +>[subseq from] Serine hydrolase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A0X3WRB9_STRVO +----EKRIAEVFAAADAEGRLHAVDIDPGREL-GLGVDDQVVIASVFKILLVLEFARQAG +AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL +DTVRLLAAELGLGRTRIVGGPRELLEVLDPRHTTSSTPRDITTLLGLIWRDRAGSPAACA +LVRELMSRQVF-RQRLASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART +ASAARTAVDAAIGRAARLAV--- +>[subseq from] Peptidase S11 family protein n=1 Tax=Flavihumibacter petaseus NBRC 106054 TaxID=1220578 RepID=A0A0E9MXD4_9BACT +-kKLEARIRPLLENFPGDAGIYVKNLRSGKTV-NIAADTVFPTASMIKIPILLGIMKKLE +KGELYYHQQLVYKDSLLYEGEDLLGSFKSGEIELSKLLLLMASMSDNTASLWLQSLAGGG +IRINQLLDSLGFVSTRMNSRTTGREAFRNIYGWGQTSPKEMSALLERIYRDALVNDTLKD +RMLRTLSRNYW-DEEALSQIPPEIQTFSKNGAVD-ASRSETVLVMAPHG-PYLFTVMTKN +LSQSNNPGWILARKLSRLLWEYf +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis sacchari TaxID=115433 RepID=A0A1I3UH62_9PSEU +---------EIFDTAGVQAWAHVRCLDCGAET-GLDADEPVVLASVVKVPLVLEFARQVA +AGQLDPADRVRATAPTRLGGAAIAGCADDVELSLRDAALFALTLSDNTAADLLFDRV-GL +DNVRSLVRELGLADTRITGAPRDVVTALDPSATNASTPRDLTRLLALIADDRAGPPEACA +WVRDLMSRQLN-WHRLTAAFPPEVAVWGKTGSLP-ALRNEIGVVSYPGGPRYAVAVCTRA +EVGRLPHVDRAIGEAARQAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Ruminiclostridium sp. TaxID=2053608 RepID=A0A3B8JCC9_9FIRM +-eALKKEIEEYISQQSAKYGMYFINLVNGDEF-GINDKDEFVAASTTKLPMNLLLYKKIA +SGEIDPESTLIYLEEDFEPGSGIIQKSEGTEYTVRETARLSIVYSDNCAINMIIRLL-GI +DNIRNYMQELGGT--------------IYYGRRHRSCPYDIALYTKELYRFYIESPEIAG +ILIDDLQNTVF-NDRINKYLPEDVKVAHKIGSFEYGVYNDVGIIFAD--EPYVLAVMSDG +AE--YGAACDVIGEISKRIYY-- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=A0A193BY81_AMYOR +--DIRERIEAVFAAAGAEGSLHAREVGDGAEV-SAGADDQVVLASVFKIPIALAYAKEVV +AGRLDETEYTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWNRL-GQ +ETICRAVADLGLTRTRLIGSCEDSFRMCDPERETSSTPRETTALLDAIWTDRAGEPEACE +RVRTIMAQQIW-PHRLSSGFPSGVRIAAKTGTLP-GIRNEAGVLTLPEGRRFAVAVFTRA +HSLDLPEVDASIGAAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces kanamyceticus TaxID=1967 RepID=A0A5J6GM73_STRKN +--DVNEQIATVFEEAGAQGFLHAREVGPGTEV-AFGADAPVVLASVFKIPVAVAYAREVA +AGRLDERERTTIPARYRIGGIGTAGCADDVEMTWRDVALFMLTMSDNAATDVLCHRL-GR +VTVEKVLAELGLSRTRLTGCCEDLFAVLDPARTSASTPRDITELLDAIWTDRAGAPEACE +RVRSMMRRQIW-PHRLTSGFASDVTIAAKTGTLP-AVRNEAGVVAYPDGRRFAVAVFTRA +ATLDLPAVDASIGRAARIAVDH- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=R4SS22_9PSEU +--DIRERIEAVFAAAGAEGSLHAREIGDGAEV-SAGADDQVVLASVFKIPIALAYAREVV +AGRLDETEYTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWDRI-GQ +ETICRVVADLGLTRTRLIGSCEDSFRMCDPERETSSTPRETTELLDAIWTDRAGEPEACE +RVRAIMAHQIW-PHRLSTGFPSGVRIAAKTGTLP-GIRNEAGVVTLPEGRRFAVAVFTRA +HSDRLPEVDASIGAAARLALDH- +>[subseq from] serine hydrolase n=1 Tax=Clostridium gasigenes TaxID=94869 RepID=UPI0014384691 +-----KEIKRYLESRIGTYGFFFEDLKSGFIY-GYNENVQMVAAGCMKLPISISLIKAVE +NGKVDFMDKIKINGEDKVYGTGIIHEFNEREYTVFELLVAMLIQSDNTATNKIIDIV-SI +KQINEDLKEMGLRNTILNRKTTDER-NNNSDIENITTASDLSKIWRHLYKASYLNKENSE +MLVDILTRQQI-KNKLALYIPDDYEISSKTGDKK-GVENDTALIRLSKGT-FTFSVLSTN +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Agromyces sp. HY045 TaxID=2651190 RepID=UPI0012ED9C5D +-qALRERIGSIEAELGVTATMHAIDVDTGEEF-GVAADDLVVPASIFKVPVLTELCCRFA +DGSIDPAQGMFIAREAFRTGDTGLSVFLDDVLSVRDLAVSMMSVSDNRATDILIDLL-GL +DAINERSRRLGLEQTVLVEDCAGLFRVLDASATNRTTPREVTASLALLWDGGVLAPAATA +EARRILSLQVW-PHRLKAGFPSRIRISGKTGTLPY-LRNEAGMIEYPDGGRYAVAVFVRE +TLEENIDADRSIGLIGRAVVDE- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-118 TaxID=1463881 RepID=UPI0004C63312 +---------------------------------GLGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVLVRAEHRLGGWGTAGCADDVELSLRDLAFFALSVSDNTAADLLLERV-GP +DTLQLLAGELGLPRTRIVGGPRQLLEMLDPARTNASTPREITRLLRLVWRDEAGPAEACA +FVRELMARQVF-RHRLVSGFPDDVVVAAKTGTLP-GLHIEAGVVTYPDGGRYAVAVFART +PDTGRTATDSAIGRAARLAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2572 TaxID=2512223 RepID=A0A4R2GZ69_9ACTN +------------------------------------ADGVVPMASVYKLPLLAAFCRLVD +LGEIDPLSRLTLDPAERTAGPTGLSVLADPVMSLRDLAVSMMTVSDNASADALLDLV-GL +RRLAELLQSFGLQRTWVRRGTAANLRVYEAANASASSPRDMTLLLQRLWAGELLSAGQTE +FVKATMHRQVF-QHRMAAGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGAAFAIAVFTLA +ARGDQPRVDTAIGEAARAAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. ARS1019 TaxID=2024878 RepID=A0A2D6Y367_9SYNE +--ALSNRWAALAANQDLKASAFMHVLDTGRYA-DFNADQPMAAASSXKTPIXLCALQLID +DGTLHWNEPLTLTKELVGGGAGWMATRPVGSFPTYEVATEMIRXSDNSATNLLIGRVGGQ +DAINMQFLELGLDATEVNNWLPDLDGT------NTTSAKDLSRSIALVDSGEVLSPRTRD +LFRAVMATSVT-NTLLPTGLMRGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAGFMVEG +PFN-DPRSTELIRQMAAAMAS-- +>[subseq from] Beta-lactamase SHV-24 n=2 Tax=Planctomycetes bacterium Pla163 TaxID=2528008 RepID=A0A518D0T5_9BACT +--ELAARLEALFEPFEGRVGLYVARLDTADAF-AFDADATYPTASLVKVPILLALYERIE +AGELDPHALLTYDAQRSRGGEDLLASFQDGAITLSKLIHLMIAFSDNTASVWLQELAGGG +AGINAWLAEHGYEHTRVNSRTAGREDDYRAFGWGQTTPREMARMLASIRRGEAVGARADE +EMYRVLCRTYW-DSEALSALPPWIQAASKQGAVNR-SRSEVVLVNAPSGD-YVFCLITAD +QVDTDNTGFVLLRDVSRVLWEHf +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora arborensis TaxID=2116518 RepID=A0A318NTR8_9ACTN +---------------------------GAREV-GVRADEQVVIASIFKILLVLEFARQVE +AGQLDPTERVLVTAADRLGGWGLAGCTDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLTRTRVLGGPRELVEVFDPAQTTSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA +DEPRRIDVDLAMGQAARTAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis saalfeldensis TaxID=394193 RepID=A0A1H8YKT2_9PSEU +---------------------------------GFGIDEPVVLSSVVKVPLVLEFARQAA +AGQLDPRDRVRARAADRLGGAGSAGCADDVEYSLRDAARLAISVSDNTAADLLFDRV-GV +ENVRSLTAELGLAGTRIFGSPRDVLRALDPACTSAGTPREMTELLSLIWRDEAGPPSACA +LVRDLMGRQVN-WHRLTAGFPAEVAVAGKTGTMP-GLRNEIGVASYPDGTDYAIAVFTRG +GSENEPAIDRAIGEAARTAVEQ- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A4Q6AA12_9BACT +--GLQRQVEEAIKGFNGDIGVYIKNLENGKIV-AVNADTVFPTASMVKVPILVGVMHKVE +RGELTLDSNLVYRDSLLYAGVDILGSLKQDEIALGKVAMLMLTMSDNTASLWLQTLAGTG +TRINEIMDSLGLKVTRVNSRTPGRENIRSIYGWGQTSPREMATLFERIANGEVINKQRSD +AMLRMLSRNYWDKH-AISQIPA-------------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Gordonia westfalica TaxID=158898 RepID=UPI0012B84FE2 +--RVDREVAETLADAGCSGWVHATTIGSPQIEySFDADAPVVLASVYKLAVLISLCRSAD +RGDIDLASSITVDPTLWAQGPTGLAAFGDPVLSRRDLAISMMTVSDNVAADVLLDEL-GL +DRVREDLVSLGAERTRIVGGVAELHEAYDAAYSSSSTPRDCTALLSAVWTDRAASPEMCA +FIRDTMRRQVF-TARLASGFPRRVTVAGKTGTLV-AIRNEIGVVEFPGELPVAVAVFTAR +SEQSLPQVDRAIGEAARTVVT-- +>[subseq from] serine hydrolase n=1 Tax=Nakamurella lactea TaxID=459515 RepID=UPI000421A15C +------RIQETFAAAGADGFLHAREIGDGPEI-AVGADDPVVLASVFKIPVAVAYAREVV +AGRLDPTERATVTARYRIGGIGTAGSADDVEMSWRDLARFMLIMSDNAATDVVFHRV-GQ +PAVDRVLEDLQLSRTQILGCCEDLFAALDPARTTSSTPREMSALLAAIWTDRAAPADACA +IVRDLMAQQIW-PHRLTSGFDNGLQLAAKTGTLPT-VRNEAGVVTYPDGRQFAVAVFTRA +HSLDQPAVDASIGSTARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis ruanii TaxID=944491 RepID=UPI000E235436 +------------------------------ES-GLGPDEPVVLASVVKVPLVLELARQVA +AGQLDPADRLRVTAADRLGGTGTAGCADDVELSLRDAAFFALSVSDNTAADLLFDRV-GL +DNVRSLLRELGLARTRVIGSPRDVVAALDPLRTSATTPRDMTTLLAAIAGDTAGPPEACR +WVRQLMGQQVN-WHRLTAAFPPQVRVWGKTGSLL-AVRNEIGVAEYPDGARYAVAVFTRA +PTSRLPDVDHAVGAAARAAIE-- +>[subseq from] Beta-lactamase class A n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A1H5MG24_9ACTN +---TQDHIRTAFADAAVTGWLHACDIDSGAEV-GFHPDHPVVTASVHKLCLLVALHQCAA +QGDFELTEQIEVPPTGRTFGLTGLGAMLDPAVSLRDAAYLMMSVSDNIAADLLLERV-GL +DAVNRTTTQLGLSHTLAIHTFRQLLDALDPARTNRSTPRDMTRLLSCIWRDEAGTPDHGA +AIRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA +ANATLPAADAVIGTAARIAVD-- +>[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Thermoanaerobacterium saccharolyticum TaxID=28896 RepID=UPI0005F05693 +-qQLKDNIETLLSQHTGNYGVYFIDLNSGETF-DINGYGSFIAASTYKVPLNFYVYTLIT +EGKLDPNMEVQYTSQDYEGGSGSIQYDPVGTYTIRELSKKSIEESDNIASNMLMRVV-GY +DNYLNFIESLGAYVVPY--------------SDNVTSPRDLSIYMEDILNYANAHSSTAG +ELLSYLENTIY-NDRISYPLPSNITVAHKIGNLSN-VVNDTAIVFYPQK-PYILTIMGNN +VDSDNSDAYTVIREISKMVYD-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. 06-1460-1B TaxID=2022501 RepID=UPI000B9B59FD +--TTDEQLRAVFADAGCRGWVRAERIDGTGTVvDHEGDDPVVAASVWKLVLLVAAGRAFD +EGSLTATDSVRLVPAQCSPPTGIASYADPVTMSWRDIARSMITVSDNAAADALLGAL-GL +NALTRVIEDLGLEQTRIVGGTKTLGDGFDPAYTSCTTPRDSNTVLRSIWLDAAASPEQCR +YMKEVLSQQVW-PHRIRSGVPPDVQVSGKTGTIGP-IRNEVAVVSFPGEKPVAVSVFTRA +ARMDLPLVDQAIGHAARIAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces melanosporofaciens TaxID=67327 RepID=A0A1H4T0C8_STRMJ +---IEKRIAEVFAEADAEGRLHAVDIDPGREI-GLGVDDQVVIASVFKILLVLEFARQAD +AGQLDPRERVVITAPGRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALVRRI-GL +DTVRLLAAELGLDRTRIVGGPRELLEVLDPRHTTSSTPRDITTLLGLIWRDRAGSPAACA +LVRELMSRQVF-RQRLASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART +ASAARTAVDAAIGRAARLA---- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI00069AB418 +--TAEARIQEAFDAAGVRGYFFAREIDGDRTL-GVAADEPVCLASVFKIPVALAYAREAA +AGRLVRTERLAVDPRYRDGGIGTAGCADPVEMSLRDLVHMMLTMSDNAATDVVLERV-GL +DTVNGLLRELGRDRTHLVGGCLELTGVCVPERTTRGTARDIAELLAQIWRDEAGPAEACA +EVREVMSHQIW-PHRMGSGFDDGYRLAGKTGTLP-GWRNEAGVVEHTDGGRWAVSVFTWS +RTPDNPAADRVIGTVARLAVDE- +>[subseq from] serine hydrolase n=2 Tax=Veillonella sp. VA137 TaxID=741828 RepID=UPI000F8ECCC1 +----------------------------------VKQSRPVRAASMIKVYILGYLFEEIE +AGHINLGETMELEESDKVGGAGVLSGAVGTKLTVDELAKLMITVSDNSATNILIRRL-GM +ESINQYIIKNGFMDTKLQRYMMDLE-AIRQGRENYTSANDLGHWFMNLLEGKGMSSSSRE +KMLMYLLGQTD-TETFNEALS-NRFIAHKTGELA-GVYHDGGIIFQSKGEAYILITLSD- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinoplanes atraurantiacus TaxID=1036182 RepID=A0A285IPZ0_9ACTN +-----------FDKVGAGAHAHVVDIDTGHDV-GARPDEQVVIASVFKILLVLEFARQAV +AGQLDPTERVLVRAADRLGGWGTAGCADDVELSLRDLAYFTMSVSDNTAADLLLRRI-GP +DVLPLLTAELGLTRTRLIGGPRQVLEVFDPEHTTSSTPREITRLLGLIWRDEAGPAAACA +MVRDLMARQMA-WTRLPSGFPPEVRVAAKTGTLP-GLHIEAGVAEYPDGGRYAIAVFART +PRTRQIDVDLAMGEAAHAAVE-- +>[subseq from] LysR family transcriptional regulator n=1 Tax=Propionibacteriaceae bacterium NML 061049 TaxID=2016501 RepID=UPI000B97AA46 +----VAQIRDVWRAVGVVGGLHARDLRSGAML-AVDADDAWPMASVAKVPLGIALHRAAD +AGLLGLDQALTLRPDGRTSGTTGISAMADPVLSLRDALYLALTISDNAAADAIWDTL-GA +DRVQHLLRQLPPDQIRLGEATRDLYDSLDGPYACRATAAGATRMLELIWSDQAASPAACA +AIRDLMRRQVW-AHRLASGFPADLEVAGKTGTAGD-HRHEIGVVSYPDGRRYAVAVFTRL +QQETSHHRDWAIGETARLAVN-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Woesebacteria bacterium RBG_16_34_12 TaxID=1802480 RepID=A0A1F7X9W0_9BACT +---VISNFRQITNNLSGVYGFYVTDLETGLSY-GVLEEEVFQAASLIKLPVMVAMYLEEE +EGSLSLSSKYKLKKSDKVAGAGSLYSKPEGYISYQELIRLMAKQSDNTAFNIARNLL-GD +GKIDEIINKIGMTKTSLQKN--------------ETTPEDIGIFFEELWNGHIINSQHKD +ELLDFMTDTLY-EEWLTAGVPVDVRVAHKYGREVH-VVNDAGIVFAD--EPFVVVIMSKG +VV--EKEADEIFPKLAKEIY--- +>[subseq from] serine hydrolase n=1 Tax=Virgibacillus siamensis TaxID=480071 RepID=UPI000984B0D4 +---LQTKIRELLNGLESQFSLYIST-KDG-DI-KISENVQRPAASLAKIPILIEALRQID +DGRLREDCSVPIKKSMLAGGAGIIAKLTNADFTYRDLLELMIIISDNTAANVVLEAV-GA +EQVNRFCSVCGCNNTILQRKFMDEA-AQMTGRDNYTSAEDMMRMLHLICSNKFISRKNRN +KIIGILSNQQL-KDKLAYYLPEDVHMFHKSGELA-GVEHEAAILEYNGNQ-LQAVVLSEG +WE-NNGDGKLFIAEIGRLLIRY- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Chloroflexi TaxID=167963 RepID=A0A5N9ES26_9CHLR +--ELINRMNAMCSESPFQSGWYLKNLQTNESA-NYYGDVVVPSASTRKIAILMNAMKWIH +EGKLSLDQPIRIDETQYVGNSSGCFQYLRPGVQLYDVLTMMIIVSDNTSTGIVANLL-GL +DSINEFSQSIGMIGTTHRHKLPPLDLDHSLDYTNSTTPNDVGLILELILLGTGSSKELCQ +IALDILLNQKL-NNKLPALLPKGTKVAHKTGTGAR-NYNDAGIIFLDDSPLFILTVFTEN +VPTSLADG--------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora cremea TaxID=709881 RepID=A0A1N6APJ0_9ACTN +-----------------TVGAAGDPAGGGREV-GVRADEQVVIASIFKILLVLEFARQVV +AGQLDPTERILVTAADRLGGWGLAGCTDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLTRTRVLGGPRDLVEVFDPSRTTSSTAREITRLLTLIWRDEAGPAEACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA +DRPRRIDVDVAMGHAART----- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. ANT_H53B TaxID=2597357 RepID=UPI0011EE48C4 +--TTDEELRAVFADAGCRGWVRAERIDGTGTVvDFEGDDPVVAASVWKIVLLVATARAFD +EGVLAATDSVRLVPAQCSPPTGIASYADPVTMSWRDVARSMITVSDNAAADALLGAL-GL +DALSQVIDSLGLEDTRIVGGTKTLGDGFDPAYTSCTTPRDSNAVLRAVWLDTAASPEQCA +YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGEAPVAVSVFTRA +ARMDLPLVDQAIGHAARVAV--- +>[subseq from] Peptidoglycan-binding domain 1 protein n=3 Tax=Thermoanaerobacterium TaxID=28895 RepID=W9EBW6_9FIRM +-qQLKDNIETLLSQHTGNYGVYFIDLNSGETF-DINGYGSFIAASTYKVPLNFYVYTLIT +EGKIDPNMEVQYTSQDYEGGSGSIQYDPVGTYTIRELSKKSIEESDNIASNMLMRVV-GY +DNYLNFIKSLGAYVVPY--------------SDNVTSPRDLSIYMEDILNYANAYSSTSG +ELLSYLENTIY-NDRISYPLPSNITVAHKIGNLSN-VVNDTAIVFYPSK-PYILTVMGNN +VDSDNSDAYTVIREISKMVYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis pretoriensis TaxID=218821 RepID=A0A1H5QBT7_9PSEU +--KVEQRISDAFLAAGARGFLHAREIGGGGEV-AVGADDPVVLASVFKIPVAVAYAREVV +AGRLDETERTRVGPRYRIGGIGTAGCADDVELSWRDLALFMLTMSDNAATDVIYHRV-GQ +EAVDRVLTDLDLHRTRLIGCCEDLFAVLDPERTTASTPREITTLLEAIWTDRAGDAAACE +RVRTIMAQQIW-PHRISSGFGSDVRIAAKTGTLP-AVRNEAGVLSYPDGRRFAVAVFTRA +DSERQPAVDAAIGKAARLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. HBUAS56017 TaxID=2571128 RepID=UPI001177D591 +-----KEIKRYLESRIGSYGFFFEDLSGGFVY-GYNENVQMVAAGCMKLPIAVSLIKAVE +DKKVGFMDRIQIKREDKVFGTGIIHEFDEREYTVFELLVAMLIQSDNTAANKIIDIV-GI +DVINTDINKMGLRNTSLNRKTNDER-NRKNNIENITTAYDLSTVWRHLYKGTFLNKKNST +MLVDILRRQQI-KNKLALYIPDDFEISSKTGDKK-GVENDTALIQVQKGT-FVFTVLSSC +IPN-SVYGTVTLAKCGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Actinoplanes atraurantiacus TaxID=1036182 RepID=UPI000BE2FAEC +------------DKVGAGAHAHVVDIDTGHDV-GARPDEQVVIASVFKILLVLEFARQAV +AGQLDPTERVLVRAADRLGGWGTAGCADDVELSLRDLAYFTMSVSDNTAADLLLRRI-GP +DVLPLLTAELGLTRTRLIGGPRQVLEVFDPEHTTSSTPREITRLLGLIWRDEAGPAAACA +MVRDLMARQMA-WTRLPSGFPPEVRVAAKTGTLP-GLHIEAGVAEYPDGGRYAIAVFART +PRTRQIDVDLAMGEAAHAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Veillonellaceae bacterium TaxID=2049049 RepID=UPI0012B9A6AE +--------------DKAAVSLYCRPLDGGDDF--FYRDRVMPSASLIKVPIMACVFRQEK +EGQLSFDAAYPVYGN--VEGGSFYDLPEGTEVSLRTLVFHMIVESDNTCTNMLIDVL-GF +DAVNEEIRRQGMEHTLLRRKMMDFEAA-RQGKENVTSPGDMGRLFLRLASGTCVDGRRDE +AMRAILAQQED-NCILPAQIPNTVAVEHKTGELD-GIYHDCGLVWKQGR-PYVCCLMADG +IV--------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces cyaneofuscatus TaxID=66883 RepID=UPI0013DA3EBB +---VERTIRSLFDDAGVRGWLHVADLHRPARV-VVDPDAQVPMGSVYKIALMTAFCRLAD +AGLVDPRHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA +EAVDGMCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPAETARLLRAIWTDEAASPESCS +FMRAAMLTQPW-THRLASGFPDDVTIHGKTGTFGS-MRHEAGVVELADGSVYTAVVFTQA +ARADLPRADAVIGAAARAAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2G6JI54_9BACT +--QLQARLMEAVKDFRGRVGFYVEHLGSGEKA-EFCADDLFPTASMIKVPILVTLFDAIE +AGRVDYEAELQYEASRLYPGNDLLGSFRDGEISIPKLILLMETLSDNTASLWLQELAGTG +TAINAWLAAHGFEKIRMNSRTPGRKPDWERYGWGQCSPREMAGLLRMIREGKAGTAWASY +RMRRALARSFW-DGRALAAIPPEYEVLSKQGAVSD-SRSEVILVHAPGGD--YVACFTTD +DQADDNEGYVLLRKLSRICWQHf +>[subseq from] Serine hydrolase n=5 Tax=Bacteria TaxID=2 RepID=A0A165E8P9_9MICO +-----DEINGVWTSLGAQGFLFAEDLETHRSV-GIRESARIPLASVGKVAIVAGLLDAAA +DGVLDLTRRVVVDPTTATPGTGISGLHDPVEMSLRDLAAMALSVSDNAAADTLFALV-GP +ERITALLHRFGIRSFDVVAPMSHLYDQLPDSAFNTGTVRATARLFELIHTGRLLGAEDSA +VLRDLLRRQIF-RHRIAAGFPDAVSYYGKTGTFLN-FRHEAGVIVDSDGTAYSIAIFTRS +TIATQPELDASIGYCARLAIEH- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces huasconensis TaxID=1854574 RepID=UPI000FD8AEBA +---------------------------PSARV-AIDPTERLPIGSVYKVPLMAAFCRLAD +AGLIDPCRRVTLEPDERVPPTGVSILSDPVTVSLRDLVVLMMTISDNASADAVLRAV-GP +DAVDALCRDLDMPDTHIHAGVVSNFSVYDPALKASSTAADMARLLRAIWTGEAASDERCA +FMREVMGKQAW-AHRLASGFPDDVAVYGKTGTFGS-LRHEAGVVELADGSAYTAVVFTQA +ARSDLPRADAVIGAAARVAVE-- +>[subseq from] serine hydrolase n=1 Tax=Microbacterium sp. URHA0036 TaxID=1298860 RepID=UPI00040EEA1F +---IGQDIAEIFADAGATGFLHARQIGGGPEV-NTGADEPVVLASVFKILVLTAFVRAVA +AGDLDPTERTTVTARYRVGGVGTAGFADDVEASWRDLALNMMTMSDNAATDVIYHRL-GA +DAVNRVVSDLGLQKTRLIGCCEDLFAAVHPLKTSHSTPREVATLLNALWTDTAAPAEACR +KARDIMALQIW-PHRLTSGFPGEVSLAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA +GSL-ADRQPLVDASIGRAAF--- +>[subseq from] Serine hydrolase n=1 Tax=Ferruginibacter sp. BO-59 TaxID=2294116 RepID=A0A3M9NGP3_9BACT +-kKLENKLRVLLSSFHGTAGVYVRNLRTGKEA-AIIADTIFPTASIVKVPILVGIFKKID +EGVYTYHQPLIYRDSIARGGSGLMQFFKDSTTEVRTLVSLMLSHSDNTAAVWCEKLAGGG +VEINSWLEKNGFRYTRVNARTPGREKMNKEYGWGQTTPREMSDLMVMIREGKTVSKAASE +QMYRDLTDVFW-DEYALSQIPPYVQAASKQGMVD-ASRSEAVLVNAPHGD-YVFYVATKN +NKETNNEAWQLARDVSSLLWNYf +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A329UB22_9FIRM +--TLEKRIAAELYSYQGKMSVFVDDL-QGRTV-EMGADEEFETASTIKAYILAVLYLQAS +RGKASLTEEIEYQPEHFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMVIDYL-GL +DTINACIKELGFAHTVLHNPLH-FDR---YEKLGTTTPRDYASLFAQVAKGTLVSAEASA +EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKD +FH--------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter sp. NFR10 TaxID=1566292 RepID=A0A1G4TVN1_9SPHI +-sKLSAKLNEAIKGFQGQVGIYVHNLKNGKTA-EINADTLFPTASMIKVSIQCGVMDKIE +KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GG +EYINNWLNQNDFKIMRVNSRVPGREAIRRIYGWGVSTPREMCRLFAMIREGKAVSPAASE +RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH +NKDT------------------- +>[subseq from] Serine hydrolase n=1 Tax=Gordonia terrae TaxID=2055 RepID=A0A2I1R717_9ACTN +------------------------------EY-CHDADTPVVLASVYKLAVLISLCRMAD +RGDIDLSASLTVDPTRWAQGPTGLALFVDPVLSWRDLATSMMTVSDNVAADVILAQI-GL +QQVRDDLVELGLTNTRIVGGVAELHEAYDAAYSSSATPRDCTTLLDAIWTDRAASAPSCE +FVRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AVRNEVGVVEFPGELPLAIAVFTMS +ARSELPEVDRAIGLVARAVVT-- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000380893C +----------HLDRIPGTVSAYLARLDAGPTW-TRHPDTTHYAASTMKVAVLVALYRALE +AERLAPDTAVPVRNEFDSAQPGAAWDRLGGTASLRWLAERMIVRSSNLATNLLLDQV-GL +PAVADVWARAGARRSSTGRGIEDFAAR-TAGITNLVTAADLAALLRDLALGALATPESCA +AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCHTG +DHPDRSADTQLLADVSAHA---- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_40CM_2_67_6 TaxID=1805068 RepID=A0A1Q7P295_9CHLR +--DLIRQLDGLVASFPGGAGVWVSDPNVPTPLfMHDPDEQVIAASLYKLGVLAEAERRVD +AGQLHYNDQVVIQPEDVTADGSFEE--AGTQLTLDEALEAMITISDNGAALALWHIL-GG +ANVDVTLQNAGIADFHVALDESE---------DHWATPRAVGMFFTLLARRQLISPAASD +RMLARLERQQI-NNRLPAQLPAGVVVAHKTGNLV-GATHDAGIIYTKSGPRVVVAMTWDA +LD---EDADNFISSVGASVYS-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Shapirobacteria bacterium CG07_land_8_20_14_0_80_39_18 TaxID=1974882 RepID=A0A2M6YRP4_9BACT +----KEAILEMIKPLRGKYGIFFQDLESKNSF-EINGEEIFTAASLIKLPVILTLYREAE +AGRINLDEVYKLQNSDKSSGAGSLQKSLGFEITFRQMAELMGKQSDNTAFNIVSRKL-GK +EKIQELIDALGMKNTSFDENE--------------TSPEDIGLFFRKLYGEGIIYEKDKD +EILSFITNTIW-EDRIPAGVPKGVKVSHKIGTEV-GVISDAGIVFAQ--KPFILVIMSQE +AN--EIEAKKALPEITKKIYE-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=UPI00077CA0C6 +------------------------------------------------------------ +------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM +TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS +KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ +VQNQAAERQ-AIGALS------- +>[subseq from] serine hydrolase n=1 Tax=Catellatospora vulcania TaxID=1460450 RepID=UPI0012D4596C +----TNRIAGAFAEADMRGWLHARDLDTGREV-AVDAHDQVVIGSIFKILLVLEFARQAA +AGSLDPADRALVRAGDRLGGWGTAGCADDVEMSLRDLAYFTMSVSDNTAADLLLHRV-GP +DLLPLLAQELGLTRTRLVGGPRELLAVFDPAQTNSSTPEEITRLLGLIWRDEAGPAQACA +EVRALMLRQLF-WTRLAAAFPPGVRVGGKTGTLP-GLHMEAGVVEYPDGGRYAVAVFAKT +EHLSMPELDLVLGRAAKLAVD-- +>[subseq from] hypothetical protein n=1 Tax=Kallotenue sp. CFH 73958 TaxID=2592335 RepID=UPI00128C34BA +-----DELTALLESAAGDYSLCVWR--DGAQVyGYREHVTRSAASLVKVPLALAIVDA-- +--GIDLDAVVILREPDRVAGDGTFDRAPAGTATVRELIGYALTESDNTASNLLIDRI-GM +DRVNAWLTQHGLA-TRLRRRFMDHES-LRAGRDNTTTAADMCAILE------LLRESRYE +WFIDLLSHSVA-DGKLEAGLPPGVRLAHKVGDLPS-VEHDAGIVFAPGS-PYVIAALAVD +LP-DSQSGRRALAAASRLVWR-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine metagenome TaxID=408172 RepID=A0A382BZA6_9ZZZZ +-aKLQTNLDRIVAAYEGVAGLHVIDLSSDDRL-AVNDDLIFPQASSIKVTILLELFRRAQ +FDPDILRKRIVMNDDVRTGGSGVLRVLTDGGLSLEDYAIYMVVHSDNTATNILIDEL-GM +DAINQLSSRLGAPRTKLQRKMIRPEES-ARGNENISTPVDAATIMAKIASCDLMDRSACV +RVREILEIYKGG--PVREPVPRQIPIAFKPGGIT-GVATVWALVGLPDR-PYVLSVMSNY +GG----NGGALIEAVSAVVYEYf +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Daviesbacteria bacterium RIFCSPHIGHO2_02_FULL_43_12 TaxID=1797776 RepID=A0A1F5KH50_9BACT +-kSLDEAVNSSLKGVAGDYSLSIKNLKTGESY-ALNEHKSYQTASLYKLWVMATVFDQIQ +KGALTESQVLSQSADILNSIDSVDAEIKGGQYTVKDALELMITISHNYAALLLSEKV-RL +SQVASFLESNGFNESKVGTDGSV-----P-----ETTAADMALFLEKLYTGKLANTENTD +KMIELLNRQRL-NNKIPKGLPAGVVVAHKTGEIGT-FTHDAGIIFTPKGD-YIEVVLTDS +QQPS--IAEDRIGALSRQVYDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudonocardia alni TaxID=33907 RepID=A0A2N0IG08_9PSEU +---------------------------TAREV-GVGAHVPVVMASVYKVFVLVAYCRAVD +AGTVDPREPVVVPVRRTPGITGISALADPVTMSWRDLVTSMVTASDNAAADVVHTRV-GR +DRVAALPAELGLTGTRIRGGTDDVFAALSPVYGSSTTAADTTALLGMLWRGELASDGSTA +FARRVLGAQIW-PHRLRAGFPAAARVAGKTGTVG-AVRNDVGVVTYPGEHPVAVAVYTHA +ARSDVPRADAAIGAAARVAVH-- +>[subseq from] serine hydrolase n=1 Tax=Pseudoclostridium thermosuccinogenes TaxID=84032 RepID=UPI000CCC4EB8 +---IKRELENYIEGFEGQYGIHFYSLYDRSEF-GINDTDEYDAASTAKLPLILLIYKKVE +KGYINLDDILTYTKEDYSEGTGVIRYDFGKKYTVRELAKLSIEESDNVATNMLKRLIGGE +KVYREFMKQSGGIVVDYDR--------------NISCPKDMSLYLKMVYDFYKENEELGG +ELMEYLQNTAF-NDRLNKLLPPNVKVAHKVGTQVR-AVHDVGIIYAE--KPYILSVMSKD +VD--EAEAPDVIANISEKVYK-- +>[subseq from] Uncharacterized protein n=1 Tax=Pseudoclostridium thermosuccinogenes TaxID=84032 RepID=A0A2K2FF95_9FIRM +---IKRELENYIEGFEGQYGIHFYSLYDRSEF-GINDTDEYDAASTAKLPLILLIYKKVE +KGYINLDDILTYTKEDYSEGTGVIRYDFGKKYTVRELAKLSIEESDNVATNMLKRLIGGE +KVYREFMKQSGGIVVDYDR--------------NISCPKDMSLYLKMVYDFYKENEELGG +ELMEYLQNTAF-NDRLNKLLPPNVKVAHKVGTQVR-AVHDVGIIYAE--KPYILSVMSKD +VD--EAEAPDVIANISEKVYK-- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003822246 +---------AHLDRMPGTVSAYLASLDATPTW-TRHPDTTHYAASTMKVAVLVALYRALE +AGRLAPDTAVPVRNEFDSAQPGAAWDQLGGTAPLCWLAERMIVRSSNLATNLLLDQV-GL +PAVADVWARAGARHSSTGRGIEDLAAR-AAGITNLVTTADLAALLRGLARGALATPESCA +AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCSTG +DHPDHRPDEDACQLIADISAR-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus aurantiacus TaxID=254410 RepID=UPI00040FA93E +--DLKREIMLLCESLTGDVSLHIRI--GDEEI-GYQSNVPLIAASLIKVPCAYALLMLSQ +EGDVDLDELIVVTDREKIGGTGVLVHMPGDVLTYRQLVSLMITVSDNTATNVIIDQV-GI +PYIQEVVDRSGCEGTKIQRKIMHTNPN-EQPLKNVMSAKDMNRFLMLIDQGTELEEGNKA +FLLSCLTGQQLIHKLFSDGLPPTAFVAHKTGDDIK-MEHNGGIIKINNKT-AYVTVMTDQ +LERN-IDGQALIQQVGKQVYDY- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-384 TaxID=1463905 RepID=UPI0004C723E8 +-----DGIPEIFERAGCEGALCVRPLEGDAEV-GLRADEPVVPASVFKVQVALEVETAFA +EGRLDPRERVTLGAADRTPGPVGLSLFEDDALSWRDLAVLMLTISDNPSTDALLRRV-GV +DALNATAARLGLTGTVVESDLRTMLDALDPSRGTRTTPRDMAELLRLIWTDRAGPAAACG +RVRDVMARQLT-RHRIAGGFRPPVRVAAKSGSLLGVVRNEIGVVSYPDGRRYAAAVFTRS +RPADDVAISRAIGAATAH----- +>[subseq from] Putative beta-lactamase (Class A) n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=A0A2H1MMI5_LACSK +------------------------------------------------------------ +------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM +TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS +KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ +VQNPAAERQA-IGA--------- +>[subseq from] Uncharacterized protein n=1 Tax=Mucilaginibacter gotjawali TaxID=1550579 RepID=A0A0X8X5H8_9SPHI +-tKLNAMLQDAVKGFNGQVGIYVHNLKSGKTA-ALNADTLFPTASMIKVSIQCGLMDKIE +KGLINYNQKLVYRDSLLYKGEDILGSFKDGDIEVSKVALLMITMSDNTASLWLQKLV-GT +DYINNWLDVNGFKVMRDNSRATGRDAMHARYGWGVTTPFEMCRLFTMIANEEAVSPAASE +RMIRNMGRIFW-DNTALSQIPPYIHTISKQGALDD-YRSETVLVNGPHGD-YVFSIITNH +NKTQDNEADELIRKVSALLWHYf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. col6 TaxID=2478958 RepID=UPI0011CD388F +------ALRAAFTDAGVTGRMHALDIESGAEL-DVCGDEVVCTASIHKLPLLVTLHERAA +AGDLDLTEQIDCPPLGRSAGPTGLAAMLDVALSLRDLAYLMMAVSDNAAADLLLDRV-GL +AAVNRTAADLGLTRTVATHSFGAMMAALDPAWANRSTPRELTRLLASIWRDTACTPENGA +AIRRLMALQVW-PHRLASGFPDDVHVAGKTGSLPT-LRGEVGVVEYPDGGRYAVAVFTRT +LSAIVPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=2 Tax=Edaphobacter modestus TaxID=388466 RepID=A0A4Q7YTA5_9BACT +--VLQQKIEAIAATHKGHVTLYATQLNTGKTV-ALDADRQVQTASVIKLTILFEAMEQVR +DGKAHWEEKLTLDKANAVTGSGVLTFFDTSLITLKDVLTMMVIVSDNTATNLAIDRF-GA +SAVNARIAWLGLKDTHLYKKIGKPATDQPQFGLGKTTAHEMEMVMERIGRCQLAGPGEEA +QPGDTMLRNQFYRNTIPRYLESGSGIASKTGSLN-AVRNDVAIVVGKSG-PMVVSIFTYG +NDTADNEAEMMIARLAKEIVESw +>[subseq from] Serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A6B9E939_LACPN +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMVRRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDEAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A346QWK4_9BACT +--ETREQIERAIADTKGKISVLWQEIGAAMPMfAYNDSRRVSAASTIKVAIMAALLEDIR +AGKRTPGDLLFVPQAGILDDTEVFDT-GERDASLFELMTWMIVSSDNTATNVLIEAA-GM +DAVNAYCAGIGLKDTVLGRRMLDFDAR-GRGLDNHTSARDQYILYNKLCRGEILDERLCA +DALGILRKQRS-GDILRRYIWEDVAVAHKTGGLDH-LCHDAGVFFLPQKTV--------- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Nocardia terpenica TaxID=455432 RepID=A0A164L040_9NOCA +--------RQIFEQAGVQGWLHARCLDCGAEI-GDGADEPVVLSSVVKVLLVLELGRQIA +AGQVDPTDRVRATAAYRLGGPGTSGCRDDVEYSLRDAAYLALSLSDNTAADLLFERV-GL +DNVRSLARELGLTRTRIAGALRDLLLALDPRRTTASTPREMTRLLDLIARDAAGPPATCA +WLRELMSLQLN-QHRLAAAFPSNALVWGKTGTLP-GLRNEIGVVEFPDGARYAVAVFTKA +RVHRLPQADRAIGTAARTAIE-- +>[subseq from] Uncharacterized protein n=3 Tax=Candidatus Woesebacteria TaxID=1752722 RepID=A0A1F7X8L4_9BACT +-qKVTSDFKKNTNNLSGVYGLLVIDLKSGYSF-GLSQGESFTAASLIKLPVMAAAFRESE +KGNLNLATIYTLKDADKIAGSGSLYYKPAGTLSYRELLMLMGKQSDNTAFGIMRKVL-GD +AKINEVIKTIGMNSTSLE--------------DNSTSPDDIGTFFKKLWEGKVTSKDSAD +EILNNLTETSF-ENWIVAGIPANVRVAHKYGRELH-VVNDAGIIYADN--PFVLVILTKG +VV--EKEADGIFSSLAGLVYD-- +>[subseq from] serine hydrolase n=1 Tax=Terrilactibacillus laevilacticus TaxID=1380157 RepID=UPI0011468887 +-----EKLDRLVSPFGNKVSVVIKE--GKNHY-SFNESTKMLSASLIKLPIFLYAFDQVK +KGTLSLDQKIPVSPEKMVDGSGIIQVIQDVRWSIRDLLGLMINVSDNTATNVLMDVL-GI +EQIQSWIENHGLNGTSIQRKMMDMQAK-KEGKENFTCASDVSHCMELIFLRPNSLSCEFP +FVKHYFLNQQF-RGKIPGKIETPVKIYNKTGEME-GISHDTAFMKLKDKT-SIVTCMTSG +FE-DATEADQLIQKMGEWVY--- +>[subseq from] Serine hydrolase n=1 Tax=Gordonia rubripertincta TaxID=36822 RepID=A0A554UPL9_GORRU +---VDRDVAGILADAGCSGWIHATTIGSPQIEySYDADAPVVLASVYKLAVLISLCRSAD +RGDVDLASSITVDPTQWAQPTGLAAFRDPVTLSRRDLATSMMTVSDNVAADVILDEI-GL +DRVADDLTSLGAASTRIVGGVAELHGAYDAAYSSSSTPRDCTTLLSAVWADRAASAEMCE +FIRDTMRRQVF-TARLASGFPRRVTVAGKTGTLV-AIRNEIGVVEFPGELPVAVAVFTMS +ARSELPQVDRAIGEVARTVVT-- +>[subseq from] Serine hydrolase n=1 Tax=Embleya scabrispora TaxID=159449 RepID=A0A1T3P732_9ACTN +---VRGRITAAFADAGVNGSLHALDIDTGREV-EVGADTLYSTASLHKLCLVTTLFREAE +AGRVELTRRLELPAGDGRSGTGVAAMLDPVTMSLRDLASLTVAVSDNAAADALWDEL-GL +DTVNATMVKLGLTRTVAIEPLRELYAALDPNRSNRGTPRDLTRLLAAIWRDEACGGEYGA +GLRRVLGLQAW-SHRLASGFPDDVRVSGKTGTLPT-MRHEAGVVEYPDGGRYAITVCTHS +ADAALPAADAVIGTVGRLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Actinopolymorpha singaporensis TaxID=117157 RepID=UPI000B83BE71 +---------------------HAVDLHEDREI-GHHSREQVALASVFKLPLLVAYARMVD +AGEIEPEATVILEPSRRTPGSTGFAAMADAVVSWRDLARSMIAVSDNAAADELLDAV-GL +HRVRSLLDDLGLHQTRITGGTRDLFDD-PADPGTVGTCQDMTSLLAAIWADRAASPGQCA +YIRTVLAQQIW-TQRLAAAFPDDVVVAGKTGTFI-ALRHEVGVVEYPNGEAYAVAVFTRS +PRNRLPAADAAIARAAKIAVA-- +>[subseq from] Serine hydrolase n=2 Tax=Thermoanaerobacterales TaxID=68295 RepID=A0A3G2R2E7_9FIRM +-eSLKLELQNYIKDRPGKISVYVKDLNSGKTL-ELGSDNVYAAASTIKLPLVLYLYELAA +EGKIDLNATLTYTQEYYTRGTGILQGEPFGGYTLRELSRLSIEYSDNVAWKMLLDFI-DH +DGLTAFEKSLGASATG---KIDGL---------YITTPRDMGRYLEELLAFSKKYPDYGN +ELLYFMEHSIF-KEGIPQDLPDGTLVAHKMGALDD-KFHDVGIVFG--KRPYIITIFTRD +GW--EAVSLQTLADISRMVYD-- +>[subseq from] Putative beta-lactamase (Class A) n=1 Tax=Lactobacillus sakei subsp. sakei (strain 23K) TaxID=314315 RepID=Q38UX1_LACSS +------------------------------------------------------------ +------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM +TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS +KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ +VQNPAAERQA-IGA--------- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=UPI0006903BDA +------------------------------------------------------------ +------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM +TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS +KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ +VQNPAAERQA-IGA--------- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI00040071E1 +--DIRERIEAVFAAAGAEGSLHAREVGDGAEV-SVGADDQVVLASVFKIPIALAYAREVV +AGRLDETEYTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWNRL-GQ +ETICRVVADLGLIRTRLIGSCEDSFRMCDPERETSSTPRETTALLDAIWTDRAGEPEACE +RVRTIMAQQIW-PHRLSSGFPSGVRIAAKTGTLP-GIRNEAGVLTLPGGRRFAVAVFTRA +HSLDLPEVDASIGAAARLAVDH- +>[subseq from] Serine hydrolase [Lactobacillus sakei] n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=A0A508UZR1_LACSK +------------------------------------------------------------ +------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM +TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS +KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ +VQNPAAERQA-IGA--------- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinopolymorpha singaporensis TaxID=117157 RepID=A0A1H1R5Y1_9ACTN +---------------------HAVDLHEDREI-GHHSREQVALASVFKLPLLVAYARMVD +AGEIEPEATVILEPSRRTPGSTGFAAMADAVVSWRDLARSMIAVSDNAAADELLDAV-GL +HRVRSLLDDLGLHQTRITGGTRDLFDD-PADPGTVGTCQDMTSLLAAIWADRAASPGQCA +YIRTVLAQQIW-TQRLAAAFPDDVVVAGKTGTFI-ALRHEVGVVEYPNGEAYAVAVFTRS +PRNRLPAADAAIARAAKIAVA-- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus sp. HMF7620 TaxID=2682977 RepID=UPI0012F7B4E9 +----------TEAGFKGEVGLRVCTLDGTELA-AWQAGLVFPAASTIKVPLLILALQEAQ +AGRLDLAARVTLRAADQVPGAGVLHELAPGLLTWQDVLTLMTVVSDNTATNLVIERL-GL +EWVGAQLPLLGFPGTRLVGKLQVPPEAQQRGERNVTTAHDQTEGLRALVAGERLDAAHTA +LALDILGRQQL-LDILGRRVPDGYRVASKSGELN-GVHHDVGVLFTP--RPLLVALLSQG +GTREHPENRDVVA---------- +>[subseq from] Serine hydrolase n=2 Tax=Lactobacillus sakei TaxID=1599 RepID=A0A6B8G4I3_LACSK +------------------------------------------------------------ +------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM +TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS +KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ +VQNPAAERQA-IGA--------- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007C1212E +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLILNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridium tepidiprofundi DSM 19306 TaxID=1121338 RepID=A0A151B4C7_9CLOT +-----KELKRYLDSRKGNFSFYFEDLKDGYVY-GFNDLVKMPCAGCIKLPVAMALFKEIE +NNKFSLDTNIRIGKDDIEEASGIIHEFKEKDYTLLELLIAMLIQSDNTAANKIIDLI-TK +ERINEIFLDMGLNDTKLVRKTSDRLST-DDEGENYSTSFELSKCYKILYEGSYLNKEHSE +RLLKILRRQQR-RNKIPFYIPKKCSIANKAGRLD-GIEADSALLTVSKGD-FIFTAMSCN +LP-NNVYGITTIARISKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00035C2B25 +----------HLDRIPGTVSAYLARLDAGPTW-TRHPDTTHYAASTMKVAVLVALYRALE +AERLASDTAVPVRNEFDSAQPGAAWDRLGGTASLRWLAERMIVRSSNLATNLLLDQV-GL +PAVADVWARAGARRSSTGRGIEDFAAR-TAGITNLVTAADLAALLRDLALGALATPESCA +AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCHTG +DHPDRSADTQLLADVSAHA---- +>[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI00143EAFE4 +---------------------------RVCEV-AVGADEPVVLASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNSAADLLLDRV-GL +DTVRLLAKELGLDRTRVVGGPRDVLEVLDPLRTNSGTPRETTELLRLIWRDEAGPPEVCA +QVRDLMSRQLF-RHRLVSGFPGGTVIAAKTGTLP-GLHTEAGVVRYPDGGCYAVSVFART +HEATGPEVDAAIGAAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Paenibacillus sp. 7124 TaxID=1850370 RepID=UPI0013ECAC44 +---SNAAIEALVEKFSGNISVRFKDIHNQTDY-CLESGTVRPTASTIKLYILGAMMEQAQ +QGMCKLSDRITVKSEVQVGGSGVLKDLLPGILTICDIATLMIVFSDNTATNMMIDLIGGI +EAVNKHIKNQGLQNSELRNRINFMEIGDDIRRLGVSTADDFIIYLEKLACGYIFDEDYTR +ATLNILSKQHY-LDLFPRYLDQGVKIMNKTGFFP-GVRCDVGLIELVGK-HYAYAVLSDN +CAHMENEASMLIGKIGRILYD-- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora globbae TaxID=1894969 RepID=A0A420EY55_9ACTN +----------------------VVDIDEGRAV-AVRADEQVVIASIFKILLVLEFARQVV +EGQLDPAERVLVTADDRLGGWGLAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA +DVLPMLAAELGLARTRIVGGPRQLVEVFDPQRTTSGTARDITRLLALIWRDEAGPAQACA +MVREWMSRQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFART +EQTRRIDVDLAMGEAARTAV--- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis circi TaxID=871959 RepID=UPI000E26BB2C +-----ETIARRAEEVGVEVRLHAAEVDGTRSL-GIGEDVPVVPASVFKVPIALELARQAA +EGTLDLGTRIAVKPGHPTPPYGLATFRHEVLMSWHDLAILMIGISDNVATDLILAEV-GK +DAVNSTLRRLGFTQTVVPQDCGELLAALQPEKSCSTTAAEMTRLLGLIWRDEAAAPQACA +DVRHWMELQVW-PHRLRSGFPDRIRTSGKTGTLP-AVRNEVGVVEYPDGGRYSVAVFTRA +EDSRVPERDAFIGFAAATAVE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID3343 TaxID=2690260 RepID=UPI001370DD01 +--AVEDRLRAVFEAAGTEGFLYVRDVDDDDEF-TFQGDSRVVLASVFKIQIALEYARQVA +AGKLDRASRHVLGDAFKEGTGIGTDSFAYDVLSVRDAAQLMMTMSDNAATDLVLGIV-GR +ENVRATLDELGFQSTGVTGCRELFDQVRDPGHAATSTPREMANLLTAIWRDEAGPAEACA +EVRDLMGRQIW-PHRLSSAFEDEIRISAKTGTLW-GVRNEAGVVEYPDGKRYAVAVFLRP +ESFRLPAVDAAIGRAAREVIDH- +>[subseq from] Uncharacterized protein n=1 Tax=Dehalococcoidia bacterium SM23_28_1 TaxID=1703395 RepID=A0A0S8CBN5_9CHLR +-----------------SYGVVVKNLVSGAVA-EVNPHKVFETASLFKLWVMYEVYKQVE +LGLVDMDEELLVTPYYASFDAGSLPVEVCDTLTVREALWAMVTYSDNASGFLLCDKV-GM +GNIHRDLQALGLTESAFRPE------------DVTSTAADMALFLEMLALGADVSREANR +EMLDLMLAQKV-RDRLPALLPPGTEVANKTGNLDE-ATHDVGIVYDPQP-TYIIAVLSDR +GAES-----EPIALLSRAVYDY- +>[subseq from] serine hydrolase n=1 Tax=Serinicoccus chungangensis TaxID=767452 RepID=UPI0013053384 +----EEQIADLLRDAGARGWVHAIPVAGRHEV-SHRADEPVPMASLYKVLLAVAWARLVD +AGDLDPRAPQVVAASDRTPGPTGLSSLEDEVVSQRDLVTLMLTVSDNAAADVLLHLV-GL +DRLRAVAADAGLEATTVHGGTGHHQRVYDPALSSTTTARDMTRLLTKLWRDELTTPERGA +WLRRAMARQAF-RHRLASGFPDDVEVASRTGSLL-ALRHEAGVVSFPGEEPIAVAVLTHA +LNQHLPDVDRVIGTIGRVAV--- +>[subseq from] Uncharacterized protein n=2 Tax=Candidatus Woesebacteria TaxID=1752722 RepID=A0A1F7Y010_9BACT +-----ESFKEKTESLSGVYGLYVIDLESGFSY-GVNESETFQAASLIKLPVIAAMYLEAE +EGTLDLDSKYRLKNSDKVSGAGTLSGKPAGYITFANLINLMGKQSDNTAFAISMNLL-GD +AKINDVIKAIGMANTSLDENE--------------TTPKDIGIFFEELWYGNIVSQENRD +KILDSLTETSF-EEWLVAGIPGGTRLAHKYGREVH-VVNDAGVVFAESRRPFVVVIMSKG +VIE--NEADEIFPELARIVYD-- +>[subseq from] Secreted beta-lactamase n=1 Tax=Streptomyces sp. FR-008 TaxID=206662 RepID=A0A0S1UGV3_9ACTN +----------------------------------LGADEPVVIASIFKVLLVLEFARQVA +AGQLDPRERVRVTRGDRLGGWGTAGCADDIELSLRDLAFFAMTVSDNSAADLLLARI-GL +DTVRLLAGELGLDRTRIVGGPRDVLEALDPLRTNASTPREITRLLRLVWQDEAGPPQACS +QVRELMARQAF-RHRLVSGFPDGVAVAAKTGTLP-GLHMEAGVIRYPDGGLYAVAVFARS +REASRTEVDAAIGATARIAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Microbacterium oxydans TaxID=82380 RepID=A0A147DZ60_9MICO +-----------------------IGVEGGPEV-TVGADEPVVLASVFKILVLTAFVRAVA +AGELDPAARTTVTARYRIGGVGTAGFADDVEMSWRDLALNMMTMSDNAATDVIYHRL-GA +EAIDRVISELALRQTQLVGCCEDLFAAVQPLRTSHSTPREVTAVLNALWTDAAAAPEACR +QARDIMALQIW-PHRLTSGFPAEVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA +ASLS-DRQPLVDASIGRAAF--- +>[subseq from] serine hydrolase n=1 Tax=Hungateiclostridium cellulolyticum TaxID=35830 RepID=UPI0001E2FB13 +-dKLKSDLGQYISKFAGQYGIHYIDLENNYEF-GINDTNEYIAASTVKVPLNYFVYKKIA +AGEVDPKKTLTYTEGDFEGGTGILQNLAGKSFTIKYLMELSITHSDNIATNMLLRHF-GR +KNLKNYMRSLGGTVV--------------KDNKNVSCPKDMAIYMKDVYEFCNSNGELGE +EFKHNLCNTVF-NDRLPKLLPKEVKVAHKVGNQIE-AVHDVGIIYTD--KPYVLTVMSKG +IV-SEEEACNVIAEISKKVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Fretibacterium sp. OH1220_COT-178 TaxID=2491047 RepID=A0A3P1Y5T7_9BACT +----TEELERTCLDFPAVASVFVLEPAGGETF-GHRADERLPSASLIKLFVLWHLFERAD +SGDLDLLEETTLSPGAVAEGGVLHRASPGARLRLEDLALLMLSVSDNTATNALIDRL-GI +DAVNASIRRLGCIKTVLGRKMLDFEAR-RRGLDNYTCAREVGELLARIAQRG-------G +RMLDLLSVQKN-VGKLPAEIPLEPLLAHKTGELP-GHEHDAGILFHRSDRPVIVAALTAG +LP-DRLSGCRLCARVGGIVYERf +>[subseq from] Serine hydrolase n=1 Tax=Caulobacter sp. 602-1 TaxID=2492472 RepID=A0A426GM96_9CAUL +-kNLQKRIEAIAARAPAVLGVAVEDLGTRQLW-AFNGDRPFPLGSAARIPILASVMAETE +SGRLPPGEILSVRDVDLSPPSAVADAWPGRQWSVAELETLA-REGDNTALDLLTRRVGGP +GGVNGWLDVKRLEHVSVDRYRRQIATARATDPRDTATPVGLVRLLEAFINRELLFKPDPA +RLLG---R---DPGYLADALPDGASIIQSAGAPRSDTNHAVAFVELKDGRRIAFVVFLTA +STADAAQREAIITDVGRAVLKEf +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535IM28_9CHLR +--DLEHNLERIANGVAAQWGIYVKFLADGAEV-CIKADTPMDTMSVIKIPVLVELFRQVD +----------ALQTEHKRFGTGVLSTLDDGSLTLRDAAMLMIIQSDNSATDLCFDAVGGP +EVVNACMRSLGLTQIQATGTCFNWFRFDGKHPFGLSSARAMGRLLEMIYRAECASDQSCA +EMLRILRLQQF-RTRIPKYLF-GTTTPHKTGDFGPFIANDVGFVEPYQRTPVIVCFFNRH +HRGIWANLEDAVARMSEKVWEY- +>[subseq from] serine hydrolase n=1 Tax=Nocardia sp. BMG111209 TaxID=1160137 RepID=UPI00039DF52A +---------------GVHGRLHARCLGTGAEI-DWGADDPVVLASIVKVPLVLEFGRQAA +AGQLDPADRVRAVAATRLGGTGLAGCADDVELSLRDAAYLALSVSDNTAADLLFDRV-GV +DNVRSLLRELGLHRTRIVGAPRDLVHALDPLRTSASTPREMTRLLAAIAHDEAGPPEVCR +WLRGLMSLQVN-WYRLAAAFPPAVAVWGKTGTLP-GLRHEIGVVEYPDGGRYAVAVFTRA +ETQRLPHVDRAIGAAAY------ +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis regifaucium TaxID=546365 RepID=A0A154MVK2_9PSEU +--DIRERIEAVFAAAGAEGSLHAREVGDGAEV-SVGADDQVVLASVFKIPIALAYAKEVV +AGRLDETEYTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWNRI-GQ +ETICRAVADLGLSRTRLIGSCEDSFRMCDPERETSSTPRETTELLDAIWTDRAGEPEACE +RVRTIMAQQIW-PHRLSSAFPSGVRIAAKTGTLP-GIRNEAGVVTLPEGRRFAVAVFTRA +HSLDLPEVDTSIGAAARLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. 6K102 TaxID=2530382 RepID=A0A4R5FMB8_9ACTN +---------DHARELGADIWLHARDLETGRSV-GVGENTSVVTASVLKVPVALELARRSV +AGEIDLTERITVPPGGVPSPYGLSVQRDDTVISYRDLAHLMIVISDNVATDLVIDRV-GK +DRVAALLAELGLTATAVPQNCAEILAALVPERTCRTTPEEITRLLAGIWRDEAAPPEACA +LVRGWMGDQIW-PHRLTSGFPDDIVISGKTGTLPL-VRNEVGVVEYADGGRYAVGVFTRA +EDPNAPYLDALLGWAA------- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0003D3D81C +----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH +QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF +SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH +AMLTILKANTD-HSKLVKNLPTRATIYNKNGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS +GERT--AQTVAMNDLGQALYR-- +>[subseq from] Putative beta-lactamase (Class A) n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=A0A2K4QEQ3_LACSK +------------------------------------------------------------ +------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM +TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS +KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ +VQNPAAERQA-IGA--------- +>[subseq from] Peptidoglycan-binding domain 1 protein n=2 Tax=Thermoanaerobacterium xylanolyticum TaxID=29329 RepID=F6BH17_THEXL +-qELKDNIETLLSQHTGNYGVYFIDLNSGETF-DINGYDSFIAASTYKVPLNFYVYTLIT +EGKLDPNMEVQYTSQDYEGGSGSIQYDPVGTYTIRELSKKSIEESDNIASNMLMRVV-GY +DNYLNFIESLGAYVIPY--------------SDNVTSPRDLSIYMEDILNYANAHSSTAG +ELLSYLENTIY-NDRISYPLPSNITVAHKIGNLSN-VVNDTAIVFYTQK-PYILTIMGNN +VDSDNSDAYTVIREISKMVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Kurthia sibirica TaxID=202750 RepID=A0A2U3ALD3_9BACL +--SLYERLNPIIQSFNGHIAVVIADHDNSRVL---NGEEQTIAASVIKVPIMLYALHEAQ +HGRLDLHKKIAITS--TVGGSGVLSALTSPPQSILNLIELMIIVSDNTASNLLLKEL-GI +QPINAFCEKLHLKQTVIERYFMDEEA-QLKGKNNYVSANDLHKLLLLIGENEVLTNDSRQ +LALNIMKNQQF-TDRLGALNDDTITIASKSGTLDL-IEHDTAIFLVGHY-RLYVTVLTSQ +LV-EVHHGTKLMADMSTII---- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000481FFDB +------------DRIPGTVSAYLARLDAGPTW-TRHPDTTHYAASTMKVAVLVALYRALE +AERLAPDTAVPVRNEFDSAQPGAAWDRLGGTASLRWLAERMIVRSSNLATNLLLDQV-GL +PAVADVWARAGARHSVTGRGIEDFAAR-TAGITNLVTAADLAALLRDLALGALATPESCA +AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCHTG +DHPDRSADTQLLADVSAHA---- +>[subseq from] Beta-lactamase class A n=1 Tax=Kribbella jejuensis TaxID=236068 RepID=A0A542EWG4_9ACTN +----NARIRAVFDDAGVRGWLHAVALDDPDATvELDADGIVPLASVYKLPLLAGFCRLVD +LGELDPRRQLTIDPSDKTAGPTGLSVFADPVASLRDLALSMMTVSDNASADALLELV-GL +RRLAAMLTEFGLHRTWVRRGTAGNLRVYEAANASASTARDLTLLLRRLWAGELLSPEQTE +FVKATMHRQVF-LHRLASGFPDEVRVAGKTGTFG-ALRHEVGVVTLPDGAAFAIAVFTLA +ARGDQPRVDAAIGEAARRAVD-- +>[subseq from] serine hydrolase n=1 Tax=Candidatus Entotheonella palauensis TaxID=93172 RepID=UPI000B7C651D +--TIEQDLNKLCDEQPFHTGWYFKNLRTGDIL-QRHGDVVVPSASTRKIAIMMTALKAVN +EGKLALDQPVVMEAKYQNNDSGCFQHLSSDFIQLRDALIMMIIVSDNTCTGAVADRV-GL +EAINALCQGIGMSGTTHRYGIPGMAGYLPAEKTNATTPADVGLLLEVILQGSGCTPELCQ +LAIDILSWQRL-RNRLPSRLPRKVKVAHKTGTTAN-NYNDAGIVYLGDEPAFILSAYTDG +VPDELPNG--------------- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Woesebacteria bacterium RIFOXYB1_FULL_38_16 TaxID=1802538 RepID=A0A1F8CUI2_9BACT +--EIISKIQAITSALSGVYGIYVVDLNGENSY-SINENHTFQAASLVKLPVMAGSLYESD +KRTLNLKTKHTLNETDKIAGSGSLYYQPAGSVTYQKLIEMMGKESDNTAFGIMSDVL-GS +EKIETHIKRLGMTNTSIDK--------------NKTTPKDIASFFKHITKDNYLSQTSAD +LLLSYLTDTIY-ENFLPASLPDDIKVAHKFGRELH-VINDAGVVYATN--PYIVVILSEG +VMES--EAEIAIPKISELIYQ-- +>[subseq from] HTH lysR-type domain-containing protein n=1 Tax=Propionibacteriaceae bacterium NML 030167 TaxID=2016500 RepID=A0A255G8N7_9ACTN +----VAQIRDVWRAVGVVGGLHARDLRSGAML-AVDADDAWPMASVAKVPLGIALHRAAD +AGLLGLDQALTLRPDGRTSGTTGISAMADPVLSLRDALYLALTISDNAAADAIWDTL-GA +DRVQHLLRQLPPDQVRLGEATRDLYDSLDGPYACRATAAGATRMLELIWSDQAASPAACA +AIRDLMRRQVW-AHRLASGFPADLEVAGKTGTAGD-HRHEIGVVSYPDGRRYAVAVFTRL +QQETPHHRDWAISETARLAVN-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus hwajinpoensis TaxID=208199 RepID=UPI00136FA119 +---VKEKILECFHGLEGNQSIYVST--TDGEI-ALHADQPVSSASIIKIAILVEALRQVD +DEKLTIDQAVQIDNVNYVGGAGVINHLSRDHWKLADLLKLMIISSDNTATNQLIDLI-GE +HNINHTMKAAGAFHSKLMRRMMDRNA-LKSGLDNMVSGKDTYLLLREFVTQHLLSQSSME +WGVEVLLQQQF-KDKFPSKISKENLLAHKTGELI-GVEHDAGILFTSNG-PVVYAFLTAG +LL-ENRYGREAIANAGRLLYDFy +>[subseq from] Serine hydrolase n=1 Tax=Jiangella asiatica TaxID=2530372 RepID=A0A4R5DIS6_9ACTN +---VMKEIAAVLGRAGTSAALHARPVDGPGEV-ALNADSVSVAASTYKISVLLELACQAA +EGTLSLTSRLRVPADRRSLPTGISAMLDDVELSLRDLALLMMQISDNTATDVVQELV-GT +DRIAARLAALGLTGTSFPHDCARLVGSIAGTTGNITTPRDMTTLVSAIWRDEAGPAQACE +EVRRVMLQQYA-PHRLSTAYRDGPVIAGKTGTFHGGIRNEVGVVDFGGGERYAVAVYLRQ +HEYDDGRADAAIGEVARLAIDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Faecalibacterium sp. CAG:82 TaxID=1262898 RepID=R6QDA0_9FIRM +--TLEKRIAAELYSYQGKMSVFVDDL-QGHTV-EMGADEEFETASTIKAYILAVLYLQAS +RGKASLTEEIEYRPEHFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMVIDYL-GL +DTINACIKELGFAHTVLHNPLH-FDR---YEKLGTTTPRDYASLFAQVAKGTLVSAEASA +EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKD +FH--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Firmicutes bacterium ADurb.Bin248 TaxID=1852886 RepID=A0A1V5U194_9FIRM +-------------PMGGTVGFYFKDLETGETF-THNEDAPLLAASVIKLPVMAEAFRRME +AGQVLADERFAVRSKDILPGCGALNFHEGIEVTFLDLVKLMICLSDNTATNLVIRRL-GM +DAINENHGRLGLSGTRLNRLLFDAEAS-ARGLENTVSAAGMGKLLELIYRGELVSKQASA +AMLDILLDQRLGRA---------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium puniceum TaxID=29367 RepID=A0A1S8T992_9CLOT +------EIKRYLESRIGTYAFFFEDLESGFSF-GYNENVQMTSAGCMKLPIAVSVIKHVE +NEKGSFLDKIKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIDIV-GI +DTINEDLEAQGLKNTKLNRKTSD-ERAVSSGIENITSALDLSKVWKHLYNSSFLNEKNST +MLMDILQRQQM-KNKLALYIPDDYEISSKTGDKAN-VENDTALIHLPKG-SFSFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. WAC 05977 TaxID=2203208 RepID=A0A429BLV2_9ACTN +---VIEKITERAKEAGVRIRLHAAEIDGTRRI-GVDEHAPVVTASVFKVPIALELAKQGA +EGGLDLGERVTVQPGHPTPPYGLATFRHEISMSWYDLAILMIGISDNVATDLILDRV-GK +EATEKTLRGLGFEHTTVAQDCGEVLRALQPEHTCATTAEEITRLLGMIWRDEAASPSACA +DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGVFTDA +VDSRVPERDAFIGFAAARA---- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis kentuckyensis TaxID=218823 RepID=UPI000A39EE45 +---------AFFEAVGVRGFLHARRLGSSESL-GCDADSPVVLASVVKVPLVYEFARQVA +AGLLDPADRVRASAADRLGGTGSAGFADDVSYSLRDAALLALSVSDNTAADLLFDRV-GV +DNVRSLLAELGLTRTSVIGAPRDVLRALDPLRTSATTPREMTTLLAAIWADDAGA----- +PVREWMAAQVS-WHRLTAGFPPEVAVAGKTGTMP-GIRNEIGVATYPDGAAYALAVFTAG +GAETRPDIDRAIGDAARAAVDQ- +>[subseq from] Serine hydrolase n=1 Tax=Arthrobacter sp. 9V TaxID=2653132 RepID=A0A653R7B3_9MICC +-------------------------IGDGPEV-SLNADEPVVLASVFKVPFAVAYSREVS +AGRLVETERTTVTSRYRVGGLGTAGCADDVEMSWRDLAFFMLAMSDNAATDVLYHRL-GQ +AAVDAVLDDLNLKHTQIIGCGEDLDHILDPARTPSSTARDIVRLLEAIWTDSAGSPEACE +RVRLMMAQQI-WRQRLASGFDGSVLVAGKTGTLP-AIRNEVGVVTYPDGRHYAVAVFTRA +ATDPQPAIDASIGQAARLAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. M71_S20 TaxID=592872 RepID=A0A498AXD4_9ACTN +-----------------------------REV-AVRADEQVVIASIFKVLLVLEFARQVV +AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA +DVLPMLAAELGLPRTRIVGGPRHLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACA +MVRGWMARQIF-WTRLAAGFPPGVRVAGKTGSLP-GLHLEAGVAEYPDGGRYAIAVFVRA +TQTRRIDVDLAMGQAARAAV--- +>[subseq from] serine hydrolase n=1 Tax=Bacillus gottheilii TaxID=859144 RepID=UPI001117E1FC +--QFNRDVQRLTSAAHGRVSLFIES--DKGVI-EIDHHALYRAASTIKIPILIEALRQAE +SGRLDLKQPISISSAHITGGAGILQSSLPAEMKLVDLLSLMIVVSDNSATNILIDLL-GQ +NQIVQCLKVMNLQETKLQRKMMDIEAG-RRGFENTTSAYDLGICLKFLIEDGLLKEESRA +LALEMMGRQQF-RKLAYSVNGSKITVYGKTGELP-GVSHDCVIVKKDHH--LLYAVVLMD +GFTQAEEALIYFSRLGR------ +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CA-126428 TaxID=2073158 RepID=UPI001304F551 +---------------------HAREIGGGPEV-AVGADDPVVLASVFKIPVAVAYAREVA +AGRLDETARTRVGSRYRIGGIGTAGCADDVEMSWRDLALFMLTMSDNAATDVVYHRI-GP +PAVDRVLADLGLHRTRLIGCCEDLFAVLDPARTTSSTPREISELLDAVWTDRAGEPAACE +RVRSMMARQIW-PHRLSSGFGSDVAIAAKTGTLP-AVRNEAGVVSFPDGRSFAVAVFTRA +NSERQPAIDAAIGRAGRLAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Jiangella aurantiaca TaxID=2530373 RepID=A0A4R5ADD5_9ACTN +------ELREAFAAAGVAGLLHAADLGDGAEV-GVDPDAAVVTASVFKIPVLVELCRQFA +TGERAPTDRLRVPAGSRTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR +ERINAGMAALGLSGTVLEEDCAGLFRVLNPEKTNRSTPRETTTLLRRIWTADGLPEQACA +EIRRIMGLQVW-PHRLTSGFPDDVRVSGKTGTLSH-VRNEVGVVEYPDGGTYAVAVFLRL +PGRENPAADRVIGTAARIAVDH- +>[subseq from] serine hydrolase n=1 Tax=Achromobacter insuavis TaxID=1287735 RepID=UPI000B01EDC0 +-qHVEAALVPLLAATPARVSLSLRDLDGGIVL-ARQADRQQPSASIIKIPILLALLEAVA +GDRYALEQPLVLPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIELL-GF +DEINQWSQRAGLTASHLQRRMMDAAA-REAGRDNFTSADDATAALCWLLRDGALPAPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG +FTLQGGEGAALLGQIARA----- +>[subseq from] Uncharacterized protein n=1 Tax=marine metagenome TaxID=408172 RepID=A0A382RA93_9ZZZZ +-dKLETAILGLIQGFNGDVGVYVRHLSSNTAV-GVNENKIFPTASMVKVPILVKIFDKIE +AGALTMDSVVIFNKALINYGDDALARFKDGEITISKLLTHMITFSDNHASLWLQDMAGSG +TAVNTWLEKNAFAHTRVNSRTVGREAEYEEFGWGQTTPREMAELLVMIRDGRAVSPSASA +DIYRHLTRIYW-DDEALSQIPPTVQAASKQGEVSQ-SRSEVVLVNAPSGD-YVFCIITNN +QATQDNEGFILIRSLSKLLWQHf +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis niigatensis TaxID=369932 RepID=A0A2N3WK39_9PSEU +---ASETIARRAEEVGVEVRLHAAEVDGTRSL-GIGEDVPVVPASVFKVPIALELARQAA +EGKLDLGTRVAVRPGHPTPPYGLATFRHEVLMSWHDLAILMMGISDNVATDLILAEV-GK +DAVNDTLRRLGFMQTIVPQDCGELLAALQPEKSCRTTAAEMTRLLGLIWRDEAAAPEACA +DVRRWMELQVW-PHRLRSGFPDSIRTSGKTGTLP-AVRNEVGVVEYPDGGRYSVAVFTRA +EDSRVPERDAFIGFAAATAVE-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. WWJCD1 TaxID=2022519 RepID=UPI000B9C274A +--TTDEQLRAVFADAGCRGWVRAERIDTGTTV-DYEGDDPVVAASVWKIVLLVAAARAFD +EGSLTATDSVRLVPAQCSPPTGISSYADPVTMSWRDIARSMITVSDNAAADALLGAL-GL +DSLATVIEDLGLEQTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSIWLGTAASPTQCL +YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPDETPVAVSVFTRA +ARMDLPLVDQAIGHAARIAV--- +>[subseq from] serine hydrolase n=1 Tax=Leucobacter celer TaxID=668625 RepID=UPI0006A7D02B +----KSRIEAILSEAGGTWHVSAR-LGGQTVY-SLNEEEAVRSASTIKLTVLLAALRAVM +SGRLLLDQQVQLP-DECVGGSGVLRLLPSVRLPLRELLVLMIAVSDNTATNAVIDLV-GF +DEINEISGAAGAEGMILARHMMDTAAV-LAGRDNLVTARGLTAIVEALIMPDILPGELAT +VAREMLGAQQF-NERIPGLLPGSLTVLHKTGELD-GICHDAGAVVLPDGRFLLISVLGVG +VGANRHTPGDTIARITREIV--- +>[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. Root1433D1 TaxID=1736463 RepID=A0A0Q7RQT4_9MICO +--------AEIFADAGATGFLHAREIGDGPEV-TFGADEPVVLASVFKILVLTAFVRAVA +AGELDPTERTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDIIYHRL-GG +EAVNRVITDLGLRSTRLIGCCEDLFAVVQPLRTSHSTPRDVTTLLNALWTDTAAPAEACR +QARDIMALQIW-PHRLTAAFPGDVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTQA +ASLV-DRQPLVDASIGRAA---- +>[subseq from] Serine hydrolase n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=A0A2L0E640_LACSK +------------------------------------------------------------ +------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM +TEINQYIQQQGYTQTKLERKMLDDA-ARSQGLDNYTSVKDVLQFLNQLYQNR--DQAPYN +KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKAND-PFAIVVLTNQ +VQNPTAERQ-AIGAL-------- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Nocardia brasiliensis TaxID=37326 RepID=A0A379A282_9NOCA +---------EIFRKAGVRGWVHARCFGCAGEN-GLEADEPVVLASVVKVPLVLEFARQVA +AGQLDPADRVRVRAADRLGGVGTAGCFDDVELSLRDAAFFALTLSDNTAADLLFDRV-GL +DNVRSLVRELGLIETRIVGAPRDIVQALDPRRTTASTPREMTRLLALIGQDLAGPAQACR +WVRDVMREQVN-WYRLAAAFPPEAQIWAKTGTLP-GVRNEIGVIEYPGGSRYAVAVFTRT +ESQRLPEVDRAIGAAAMAAID-- +>[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora endophytica TaxID=1642495 RepID=UPI00101BB4A4 +---LRRALESAATSTDGVWGFAVRE--RGETVvSVNGDVAMRAASTIKVPLLILALQDVA +AGHRELSDVLVV-PGERVGGAGVLRLMPSVRLRLDETLELMIGVSDNNAANMVIDML-GV +DDAAARITALGARSTHLGRRLYDVE-AMRAGLDNVTTADDQALLLGLLGSTGLLPDDLRT +IALDILGRQQF-NDRIPAALGPDIVCRHKTGELA-GVRHDVGILEFDGRS-VVFTALGSG +LTDPTGVAGAVIATAARAVVD-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium polynesiense TaxID=1325933 RepID=UPI000590EDC4 +------EIKKYFESRIGNYSFYFEDLNSGYVY-GYNENNKMTAAGCMKLPIAMVLLKEIE +NMKYKLDDKIFISEEDKVYGTGIIHEFLPREYTLDELMKAMLIQSDNTASNKIINII-GK +DRINEVIKEMGLSNTVLNRRTSDEIYD-DNNDENITTSYDLCKCWKMLYRESFLSKELSS +KLLRVLGRQQLKSKSSLYILNLKINIANKTGDKQ-GVENDTVLITMPKGT-FSFTVMSSK +IPNS-VYGIVTIAKAGKMMFD-- +>[subseq from] serine hydrolase n=1 Tax=unclassified Microbacterium TaxID=2609290 RepID=UPI0004933CAE +--ETSAQIAEIFAGAGATGFLHAREIGDGPEV-TVGADDPVVLASVFKILVLTAYVRAVA +AGELDPAARTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDVIYHRL-GT +EAMDRVIADLGLADTRLIGCCEDLFAAVQPLRTSHSTPRDVTTLLNALWTDTAAPAEACR +QARDIMALQIW-PHRLTAGFPGEVRIAAKTGTLPT-WRNEAGVVTYPDGRRYAVAVFTRA +ASL-ADRQPLVDASIGRAAF--- +>[subseq from] serine hydrolase n=1 Tax=Virgibacillus ndiopensis TaxID=2004408 RepID=UPI000C077E60 +-nQLESTIHSLVNKVMDHFSIFIRTADGNIT---INAHEPRKAASVIKFPMLIEAFRQIE +NKTLNPDALVYIENTMRVGGAGIISYLTNLNYSYKNLLELMIIVSDNTAANIILDKI-GS +QNVNTLSTRLKCMETYIGRKFMDQKAQ-MNGIENYTSAVDMVHYLELIAKPNVISENSRM +QILDILSHQQF-KDKLPYYLDDNIDIFHKTGELP-GIEHDVALLNYKEQT--VYAVILTE +GFENNAHGKKYISEIGKYLIEY- +>[subseq from] Serine hydrolase n=1 Tax=Rummeliibacillus sp. TYF005 TaxID=2058214 RepID=A0A3N6BPB9_9BACL +--QLAVECQKIINSYDYQVSVAIID--GEQSF-LYKEDQLFRAASTIKIPILLASYLNLN +---DRLDTVATIPEELIVEGAGVIPFITGKLFTYRNLMELMIIVSDNTASNALLHSN-SM +HHVNHLMQKIGCKGSKIERYFMDE-SAVQNGFDNYTTAKDMILMLQQIGEGGVLNDSQRS +DALRILGNQQF-EDMLPATFDEEIRYYHKTGGLT-GVDHDVAIINYRQKK-LYVAVLTQG +WN-DGFTGKKCIAEIGKVIVDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Clostridium amylolyticum TaxID=1121298 RepID=A0A1M6KVX9_9CLOT +------EIKKYFESRIGNYSFYFEDLNSGFVY-GYNENVKMTAAGCMKLPIAIALLKEVE +NLNFNLNDKILIGQEDKVYGTGILHEFLEREYTLYELMVAMLIQSDNTASNKIINLV-GK +EKINESIREMGLKNTVLNRRTSDEIYD-DNNDENITTSYDLCKCWKILFEKKYLNQELSD +MLIDILKRQQL-KNKSALYIPDDLKISNKTGDKK-AVENDTMFINIEKGT-FAFSVMSNE +IPNS-VYGIVTIAKAGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NBRC 110035 TaxID=1547867 RepID=UPI0005A6007A +-------------------GAGAWAEPDGREV-GVGADDPVVLASIFKVLLVLEFARQAV +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLSRV-GL +DTVRLLAAELGLERTRIVGGPRDLLEVLDPRHTTASTPREITRLLRLIWTDAAGPPEACA +FVRDLMARQVF-RHRLVSGFPDDVVVAAKTGTLP-GLHMEAGVVRYPDGGCYAIAVFART +HDASRPTVDAAMGRAAETA---- +>[subseq from] Serine hydrolase n=2 Tax=Kribbella soli TaxID=1124743 RepID=A0A4R0H9A8_9ACTN +----NARIRGIFEDAGVRGWMHAVSLDEPEASvELDADAVVPMASVYKLPLLAGFCRLVD +LGELDPRERVTLEPSARTAGPTGLSAFADPVLSLRDLALSMATVSDNASADALLDIV-GL +RRLAEILESFGLRRTWVRRGTAANLRVYEAANASAASARDLTLLLRRLWAGELLSASQTE +FVKTTMHRQVF-LNRLASGFPDGVRVAGKTGTFG-ALRHEAGVVTLPGGAAFAIAVFTHA +ARGDQPRVDAAIGEAARVAVD-- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Gordonia rubripertincta TaxID=36822 RepID=A0A222TD73_GORRU +---VDRGVAEVLADAGCSGWVHAATIGSPQIEySFDADAPVVLASVYKLTVLISLCRSAD +RGDIDLASSIRVDPTQWAQGPTGLAAFGDPVLSRRDLATSMMTVSDNVAADVILDEI-GL +ARVREDLVSLGADSTRIVGGVAELHEAYDAAYSSSSTPRDCTTLLSAVWTDRAASAEMCA +FIRDTMRRQVF-TARLASGFPRRVTVAGKTGTLV-AIRNEVGVVEFPGELPVAVAVFTLS +ARPALPHVDRAIGEVARTVVT-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. CNZ280 TaxID=2586994 RepID=UPI001422ECD5 +--------------------------DGGREV-AVRADEQVVIVSIFKILLVLEFARQVV +AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLSRTRIVGGPRQLAEVFDPAQTTSSTAREITRLLGLIWRDEAGPAEACA +MVREWMSRQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARM +ADTRRIDVDLAMGEAARTAV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8U5W9_9BACT +--RLEREIERVSKIAGGVVGASAVHLETGRKV-SLHGDERFPMASTFKIPIAVQLLHRID +AGEVKLDQMVELRASDLHPGSGTLTDLFSKPLSVRNLMELMLLISDNSATDILLRLAGGA +DAVTTRMRGLGITGINVSRPTARLIADREGVPENQWSPEMWTKLL--------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Lactobacillus nasuensis JCM 17158 TaxID=1291734 RepID=A0A0R1JGY3_9LACO +---------------PARWTVAVRALNGGAYVaDWTPASHQFSASTIKLYILIRYYQLLQ +AKQINPSTQYTLRQQDVVQGSGVMLHKLGTTYTLQELVNLMIRQSDNIATNVMMDEVGGF +AAVNKTIAQVPDHETSLERKMMDTSH-LENGKANRINAEEAVDTLLKMKQGKIVSPAADK +AMLALMLHTKN-RTKLPSQLPTGAVAYNKSGESNRGIENDMAIIDYRGQT-FAVCALIEM +DGEHDA----------------- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. AMSO12t TaxID=2650410 RepID=UPI00124B8353 +------------------------------EV-AVRADEQVVIASIFKVLLVLEFARQVV +AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA +DVLPMLAAELGLPRTRIAGGPRHLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACA +MVRGWMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAVAVFVRA +TQTRRIDVDLAMGQAARAAV--- +>[subseq from] Uncharacterized protein n=2 Tax=Lactobacillus fuchuensis TaxID=164393 RepID=A0A0R1RTQ9_9LACO +------------------------------------------------------------ +------------------------------DSTVTTLITAMIQYSDNNATNQLIDYV-GM +PKINQYLQEQGYQQTKLERRMLD-NAARAQGLENVTSVTDTLNFLKQLYQDQTRYPA--N +QMLAILKGQQV-RTKIPSQLPAGTVVANKTGELAD-VENDIGIVYRTDN-PYIIVVLTNQ +VSNTS-AERQAIGQLSLAA---- +>[subseq from] serine hydrolase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=UPI0007BF803F +-qHVDAALTPLLAATPARISLSLRDLDGGVVL-ARHADRMQPSASIIKVPILLALLEAVA +NGRYALEQPLALPAAERAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWNQRADLEATRLQRRMMDAAA-REAGRDNYTSAGDATAALCWMLRDGMLPQPLRT +FALDLLADQRERAHS-LAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVALAVLADG +FT--------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces agglomeratus TaxID=285458 RepID=UPI00086F0925 +-----ERIREVFAGAGAEGLLHAVPVGTEEEV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAISVSDNSAADLLLARV-GL +DTVRLLAGELGLGGTRIVGGPRDVLEVLDPLRTNASTPREITRLLRLVWRDEAGPPEACA +HVRDLMMRQAF-RHRLVSGFPDEATVAAKTGTLP-GLHMEAGVVRYPDGGSYAVSVFART +RDASRPVVDAAIGASARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus equicursoris TaxID=420645 RepID=UPI0012B2E782 +------------------------------------------------------------ +------------------------------------------------------------ +------ARTLGVSPSSFAQDYDSAFDAYEASGENVGTLRAYGDLLASLHHGGMLDREQRQ +TLREVMQRTRSGEQRLKRGMGREVTLAHKTGTQHR-RSCDAGIATRDGVQHWVIVACSRG +PL-ALSAHEQALTRVGEALHD-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Dormibacteraeota bacterium TaxID=2052315 RepID=A0A2W6BF60_9BACT +---FVQNLQSYLSRAGGSYGVYVESLKSGATV-GAGQDSGLEAASVIKVPEALYLLHQVD +AGQVKLIDEVDLKDGDFMSGTGTLTAHTGDKFTVQDLLTLLIRQSDNTAWRALDRIL-GI +AAVDAFAASIGAPD---------CHQV-----SDNCTAREAGRMLSQLARGRLLTPGSTQ +LLMGLLETTVF-NDRINYYLQ-GVTVAHKVGMDG-GVINDCGVAFLPGD-PLTICIFTTT +GDPN--LGVQVIRDVTRAAVHYy +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=A0A1H2G6C9_9PSEU +--EITEKINERAKEVGVRVRLHAAEIDGSRQI-GVDEHAPVVTASVFKVPIALELAKQGA +EGALDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILDRV-GK +EATEKTLRDLGFEHTTVSQDCGEVLRALQPEHSCATTAEEITRLLGLIWRDEAAAPAACA +DVRRWMDLQVW-PHRLRSGFPDGIRVGGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] serine hydrolase n=1 Tax=halophilic archaeon NEN6 TaxID=2558241 RepID=UPI0010C18EC3 +-nELRSTARTIDERLDGRLGIVVCDVGSDRAIeAIRSRNRFGAASVVKLPILYALYRTYD +GRLEALERRHPIAPENRVGGAGLFHLLSDPTPTVEDLATAMIAVSDNAATNELIDHL-GF +DAIDEGAADLGLEGTHLGRKMMQTPASNGHRYVNWVTPQDCAALLSDIHRERTLSSAAYE +RLARPLAHQHD-GSMVPRYLPPNAEIRHKTGSLPS-VAADAGLLTVGER-TVAYAICCDG +LER-RGDGVDAIAELGEGVY--- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces hundungensis TaxID=1077946 RepID=A0A387HEV3_9ACTN +----RSRITAAFTDAGLSGALCATDIDHGTTV-TLAADTPVSTASVHKLCLVATLYREAA +AGRLDPTTPVDIPAAARAPPTGLAVMRDAARLSLRDLASLAIAVSDNAAADILWDHL-GL +DTVNATMAALGLPRTIAVHNQAGLYAVLDPHRTNRSTPREITALLTAIWRDDLCPPPWAE +ELRAVLGVQAW-SHRLASGFPDDVRVSGKTGTLPT-QRHEAGVVEYPDGGRYAVAVFTRA +ASVTLPAADAAIGRAARIAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_40CM_4_69_19 TaxID=1805078 RepID=A0A1Q7HHB3_9CHLR +--DLIRQLDGLVASFPGGAGVWVSDPNVPTPLfMHDPDEQVIAASLYKLGVLAEAERRVE +AGQLHYNDQVVIQPEDVTADGSFEE--AGTQLTLDEALEAMITISDNGAALALWHIL-GG +ANVDVTLQNAGIADFHVALDESE---------DHWATPRAVGMFFTLLARRQLISPAASD +RMLARLERQQI-NNRLPAQLPAGVVVAHKTGNLV-GATHDAGIIYTKSGPRVVVAMTWDA +LD---EDADNFISSVGASVYS-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. BK438 TaxID=2512151 RepID=A0A4R2PXT4_9ACTN +-----TALRAAFTDAGVTGRMHALDIVSGAEL-DLYGDESVCTASIHKLPLLVTLHEQAA +AGDLDLTEQIDCPPLGRPAGPTGLAAMLDVALSLRDLAYLMMAVSDNAAADLLLDRV-GL +DAVNRTAARLGLSRTIATHSFGEMMAALDPAWANRSTPRELTRLLAAIWRDEACTPENGD +AMRRLMALQVW-PHRLASGFPDDVHVAGKTGSLPT-LRGEAGVVEYPDGGQYAVAVFTRT +LSAIVPAADAVIGTAARIAVD-- +>[subseq from] serine hydrolase n=2 Tax=Pseudonocardia TaxID=1847 RepID=UPI000919FCFB +---------------------------TAREV-GVGAHVPVVMASVYKVFVLVAYCRAVD +AGTIDPREPVVVPVRRTPGITGISALADPVTMSWRDLVTSMVTASDNAAADVVHTRV-GR +DRVSALPAELGLGGTRIRGGTDDVFAALSPVYGSSTTAADTTALLGMLWRGELASDGSTA +FARRVLGAQIW-PHRLRAGFPAAARVAGKTGTVG-AVRNDVGVVTYPGEHPVAVAVYTHA +ARSDVPRADAAIGAAARVAVH-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536Q9H7_9CHLR +--DLIRQLDGLVASFPGGAGIWVSDPNVPTPLfMHDPDEQVIAASLYKLGVLAEAERRVD +AGQLHYNDQVVIQPEDVTADGSFEE--AGTQLTLDEALEAMITISDNGAALALWHIL-GG +ANVDVTLQKAGIADFHVALDESE---------DHWATPRAVGMFFTLLARRQLISPAASD +RMLARLERQQI-NNRLPAQLPAGVVVAHKTGNLV-GATHDAGIIYTKSGPRVVVAMTWDA +LD---EDADNFISSVGASVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. CAG:82-related_59_9 TaxID=1897006 RepID=A0A1Q6Q8V5_9FIRM +--TLEKRIAAELYSYQGKMSVFVDDL-QGHTV-EMGADEEFETASTIKAYILAVLYLQAS +RGKASLTEEIEYQPEHFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMVIDYL-GL +DTINACIKELGFAHTVLHNPLH-FDR---YEKLGTTTPRDYASLFAQVAKGTLVSAEASA +EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKD +FH--------------------- +>[subseq from] serine hydrolase n=1 Tax=Serratia TaxID=613 RepID=UPI000D154BC5 +------------------------------------------------------------ +------------------------------------------------------------ +------MRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGAVLSDSSKA +QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK +ADTSLDERSAVIRTLGSHIFDEy +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. N1-1 TaxID=2682541 RepID=UPI00135C0FE9 +---VKEKILECFHGLEGNQSIYVST-PDG-EI-ALHADQPVSSASIIKIAILLEALRQVD +DEQLSIDQVVQIDNVNYVGGAGVINHLSRDHWKLADLLKLMIVSSDNTATNQLIDLV-GE +DHINHTMKAAGAFHSKLMRKMMDRNA-LKAGVDNMVSGKDTYLVLREFVTQHLLSKSSME +WGVEVLFQQQF-KDKFPSKISKEKLLAHKTGELN-GVEHDAGILFTSDG-PVVYAFLTAG +LL-ENRYGREAIANAGRLLYDFy +>[subseq from] Serine hydrolase n=1 Tax=Embleya scabrispora TaxID=159449 RepID=A0A1T3NPC7_9ACTN +----TQRIRAIFDAARVDGFLHVRDLDTADEI-AYQADDPVVLASVLKVPIVLEYARQAA +DGRLDRAGRHLVTAADREGGIGTDGCMYDVEMSARDLAFMMITQSDNAATDIVLRLV-GR +DNVRATLDALDCRDTSVTGCKDLFQSVRDPKRTAATTPREITKLLAAIWRDEAGSAEACA +EVRDIMGRQIW-PHRLASGFADEIRVSGKTGTLW-GVRNEVGVVEYPDGKRYAVGVFLRL +ESFRAPAADASIGLAARAAIDH- +>[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI00083AFAE8 +-qHVDAALTPLLAATPARVSLSLRDLDGGVVL-ARQADRMQPSASIIKVPILLALLEAVA +KGRYALEQPLALPAAERAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWNQRANLEATCLQRRMMDAAA-REAGRDNYTSAGDATAALCWMLRDGMLPPPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVALAVLADG +FT--------------------- +>[subseq from] serine hydrolase n=1 Tax=Actinocatenispora sera TaxID=390989 RepID=UPI00068AAC5F +-------LTDTLDAAGGTVSVYAGPLSGPPAF-TRLPDEPHYAASTMKAAVLATAYRLAE +AGAVELDEPLAVHDEFTSAD---AWARLGDTAPLRWLLRRMIIRSSNLATNLVLERI-GT +HALANTLRDAGATRMVVARGIEDAA-AVDAGLDNLVTAGDLARLLAAIADRRIASARHCD +EMMGILLDQEC-TEDLAAGLPPGTRIAHKNGWVER-IRHGVGVVLPDDAPPYAIAVCTTT +DLPD-AQACALLAEVSAAAWA-- +>[subseq from] Serine hydrolase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=A0A2M9H1M2_9BURK +-qHVDAALTPLLAATPARVSLSLRDLDGGVVL-ARQADRMQPSASIIKVPILLALLEAVA +KGRYALEQPLALPAAERAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF +DAINQWNQRANLEATCLQRRMMDAAA-REAGRDNYTSAGDATAALCWMLRDGMLPPPLRT +FALDLLANQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVALAVLADG +FT--------------------- +>[subseq from] Beta-lactamase related protein n=2 Tax=Catenulispora TaxID=414878 RepID=C7Q8V4_CATAD +---ASARITAAFADAGVTGQLHALDIDTGASV-SVAATQLAATSSLHKVCLLAAFYREAA +AGRLDRTRQIDITAAERTPLSGIAVMRDAVRLSLRDLATLVVAVSDNAAADILWREV-GF +ATVNRTMAELGLSDTVAVHSMADIRDVLSPTQTNRSTPRQMAELFAAVWRDEVCTGDLGE +ELRAVLGGQAW-THRMSSGFPDDVRVSGKTATLPT-LRHEAGVVEYPDGGRYAVAVFTRA +ASAVLPAADAVIGTAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=UPI0009A05AA5 +--------GAVLAQADAGIQLHAVDLDTGGEV-AVAADQQVVIASVAKILIVLEFARQAA +AGQLDPGAHVTLRAEDRLGGWGIAGCADDVDISLRDCAYFAMSLSDNTAADALIRRV-GG +DAVRMLVAELGLDRTRFLGGPRHLLRVFDPRRTTSSTARDMTRLLGLIWHDRAGTADACA +AVRRLMTRQLS-STRLASGFPPPVTVAAKSGTLP-GMHMEAGVVRYPDGRRYALAVFATA +RDTRPADLDETIGRVAHAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Kribbella shirazensis TaxID=1105143 RepID=UPI00141DDEA4 +----SARIRAVFEDAGVRGWLHAVALDEPESTvEVDADGMVPLASVYKLPLLTGFCRLVD +LGELDPRRRVTLEPSERTAGPTGLSVFADPVVSLRDLALSMMTVSDNASADALLDIV-GL +RRLAGMLESFGLRRTWVRRGTAGNLRVYEAANASASTAREMTLLLRRLWAGDLLSPEQTE +FVKATMHRQLF-LHRLASGFPDEVRVAGKTGTFG-ALRHEVGVVTLPGGAAFAVAVFTLA +ARGDQPRVDAAIGEAARVAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. 06-235-1A TaxID=2022508 RepID=A0A260BMU9_9NOCA +--TTDQQLRAVFADAGCRGWVRAERIDGTGTVvDIEGDDPVVAASVWKIVLLVAAARAFD +EGFLTATDSVRLVPAQCSPPTGIASYADPVTMSWRDIARSMITVSDNAAADALLGAL-GL +NAATRVIDDLGLKHTRIVGGTKALGDGFDPAYTSCTTPRDSNAVLRAIWSGAAASSEQCE +YMKHVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGEEPVAVSVFTRA +ARMDLPLVDQAIGSAARIAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1D8DX91_9BACT +--RLESELIAIAGEYSGTCTWSLTHLATRDHI-ARDEGRVMPTASLIKVPVLAALYAAAE +AGGFALTDRITYAQEHRCLGSGVLSKLTPGVMTVRDAAVLMMTISDNSATNMCIDLV-GI +EAINAGMRSLGLDRTTLFYRLGDRTPGLDARRMSVSTAGEMVGLMTLIAGHACVSADASE +DMLRIMRRSDY-RHELSAELPKVAWVAEKGGSFLNGVRTCAAVFHGPRG-SFVMSAFCEG +GTGRSSEGNRTIGRLGKAAWD-- +>[subseq from] PfkB domain-containing protein n=1 Tax=Microgenomates group bacterium GW2011_GWB1_44_8 TaxID=1618505 RepID=A0A0G1MA94_9BACT +-----EELGKLLSTYTGTYGVFVEDLQSGFSY-GVKEDEEFPAASQMKLPIILAVYLEYE +KGNLNLDAPYTLLKSDKIEGTSLASFKDGSNFTYRKLIEFSARNSDNSAIRILWRKL-GN +ERIRESLIVGGMKNSSFE--------------NDITTPKDIGNFFSLLYRDMLLRKEQKE +ELIGFLTNTIS-EDRIPAGLPAGTRVSHKIGTED-GAYSDSGIIFG--KKPFILVVMSKG +AN--FKEAPSAIAKIAQTVWS-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces tsukubensis (strain DSM 42081 / NBRC 108919 / NRRL 18488 / 9993) TaxID=1114943 RepID=I2N3F0_STRT9 +-----ARIAAAFTGAGVTGWLHARDIDTGAEV-DAGADRPVVTASVHKLCVLVALHEAAA +AGRLDLTEQTEIPAHGRTPGPTGLGSMLDGALSLRDAAFLMMSVSDNAAADVLLERV-GL +DAVNATTRRLGMPRTEAVETFGSFLGALDPARTNRSTPRDMTTLLAAVWRDEAGAPDHCA +AMRRILGLQVW-PHRLASGFPDDVQVAGKTGSAPT-LRNEVGVVAYPDGGRYAVAVFTRA +AS--------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces antimycoticus TaxID=68175 RepID=UPI000A38D48A +----EKRIAEVFAAADAEGRLHAVDIDPGREL-GLGVDDQVVIASVFKILLVLEFARQAG +AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL +DTVRLLAAELGLGRTRIVGGPRELLEVLDPRHTTSSTPRDITTLLGLIWRDRAGPPAACA +LVRELMSRQVF-RQRLASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART +ASAARTAVDAAIGRAARLAV--- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. CNZ309 TaxID=2035247 RepID=UPI000C6FD6D4 +--------------------------GGGREV-ALRADEQVVIASIFKVLLVLEFARQVV +AGQLDPRERVLVTAADRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA +DVLPMLAAELGLPRTRIVGGPRQLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACG +MVRGWMARQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVVEHPDGGRYAVAVFVRA +RQTRRIDVDLAMGQAARTAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ309 TaxID=2035247 RepID=A0A2N3ZAX0_9ACTN +--------------------------GGGREV-ALRADEQVVIASIFKVLLVLEFARQVV +AGQLDPRERVLVTAADRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA +DVLPMLAAELGLPRTRIVGGPRQLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACG +MVRGWMARQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVVEHPDGGRYAVAVFVRA +RQTRRIDVDLAMGQAARTAV--- +>[subseq from] LysR family transcriptional regulator n=1 Tax=Propionibacteriaceae bacterium NML 150272 TaxID=2016504 RepID=UPI000B963D6E +----VAQIRDVWRAVGVVGGLHARDLRSGAML-AVDADDAWPMASVAKVPLGIALHRAAD +AGLLGLDQALTLRPDGRTSGTTGISAMVDPVLSLRDALYLALTISDNAAADAIWDTL-GA +DRVQHLLRQLPPDQVRLGEATRDLYDSLDGPYACRATAAGATRMLELIWSDQAASPAACT +AIRDLMRRQVW-AHRLASGFPADLEVAGKTGTAGD-HRHEIGVVSYPDGRRYAVAVFTRL +QQETPHHRDWAIGETARLAVN-- +>[subseq from] Beta-lactamase n=1 Tax=Firmicutes bacterium CAG:145 TaxID=1263005 RepID=R6F0E8_9FIRM +--ELRDNILEELAAMEGRVGFYFKNLVTGENL-GYNQREQFLSASIVKLPLLAAMFLMRE +RGETDFREKITIKRDEKLPGCGVVSYMTGDELDIETLYKFMIVISDTTATNALYKHY-GN +DAVISALKELGLEGTQFNRAFYDSIRE-EKGIQNYFVPEEIGELLEKMYDRRLVSEKVSE +EIEKILLQQQV-NHKMGGMLPIGFPIAHKTGEEED-KSHDVGIVYVKE--PFIACFA--- +----------------------- +>[subseq from] Beta-lactamase regulatory protein BlaB n=2 Tax=Microbacterium oxydans TaxID=82380 RepID=A0A3S9X6F4_9MICO +--------AEIFADAGATGFLHAREIGDGPEV-TFGADEPVVLASVFKILVLTAFVRAVA +AGELDPTERTTVTARYRIGGVGTAGCADDVEVSWRDLALNMMSMSDNAATDIIYHRL-GG +EAVNRVITDLGLRSTRLIGCCEDLFAVVQPLRTSHSTPRDVTTLLNALWTDTAAPAEACR +QARDIMALQIW-PHRLTSAFPGDVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTQA +ASLV-DRQPLVDASIGRAA---- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. 5R2A7 TaxID=2202421 RepID=A0A317CRF9_9ACTN +------RIEAIFAGAGVTASLHAVDLDDGREI-GVRADEQVVIASIFKILLVLEFARQVV +AGQLDPTERILVTAADRLGGWGLAGCTDDAEVSLRDLGYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLTRTRVLGGPRDLVEVFDPSRTTSSTAREITRLLTLIWRDEAGPPEACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA +DQPRRIDVDLAMGNAART----- +>[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora endophytica TaxID=1642495 RepID=UPI00101C7AE4 +----------------GHLHATALH-DRRREI-GVLPDEQVVLASVFKLPLVIAFAQMVD +AGEIDAAEQTTLDASERSPGPTGFAAMVDPVVSWRDAARSMMAVSDNAAADALLDVV-GL +GRVSGALDSLGARSTRIVSGIRDFYTDPANPRNNVGTCRDMTRMLEAVWRDRAASSEQCA +FIRGVMAQQVW-AQRLSAAFPDDVVVSGKTGTFV-ALRHEAGVVEYPNGESYAVAVFTMS +TRARLPAADAAIAQAAKLAVA-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3A0AT83_9CHLR +--KLQQEIERAATAFPGVVGVAVTSLRHEAGC-AVQAEEVFPAASTIKLPILVQLLMRAR +SGEADLAQRVTVPAASHVLGSGVVAYLAGPVLSLLDLAILMVIVSDNTATNLCLEVA-GL +GATNALLDRLGLHQTRVRRKMMDQVAA-VRELENVATPAELVQLLRLLDAGQP-DPQAAA +QALAILKKPK-------------------------------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000BEF6870 +-----------------------------GEV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL +DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA +QVRELMARQAF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART +REASRTAVDAAIGATARIAVDH- +>[subseq from] serine hydrolase n=1 Tax=Clostridium nigeriense TaxID=1805470 RepID=UPI00082D1E9C +-----KEIKKYLESRIGTYGFFFEDLKSGYIY-AYNENVQMIAAGCMKLPIAVSLIKSVQ +DKKIDFLDKIKIDGKDKVYGTGIIHEFNEREYTLFELLVAMLIQSDNTAANKIIDIL-GM +ENINNDIRAMGLKNTVLNRKTTD-ERNCKDEIENMTSAYDLAQIWKHLYNGTYLNKENSQ +MLIDILMRQQI-KNKLALYIPDDYEISSKTGDKN-GVENDTELIRLSKGN-FSFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] LysR family transcriptional regulator n=1 Tax=unclassified Propionibacteriaceae TaxID=185283 RepID=UPI000B97B919 +----VAQIRDVWRAVDVVGGLHARDLRSGAML-AVDADDAWPMASVAKVPLGIALHRAAD +AGLLGLDQALTLRPDGRTSGTTGISAMADPVLSLRDALYLALTISDNAAADAIWDTL-GA +DRVQHLLRQLPPDQVRLGEATRDLYDSLDGPYACRATAAGATRMLELIWSDQAASPAACA +AIRDLMRRQVW-AHRLASGFPADLEVAGKTGTAGD-HRHEIGVVSYPDGRRYAVAVFTRL +QQETPHHRDWAIGETARLAVN-- +>[subseq from] Beta-lactamase class A n=1 Tax=Desulfallas geothermicus DSM 3669 TaxID=1121426 RepID=A0A1I6D4M3_9FIRM +--PLQEQVVAYLARQPGTYGLYFIDLNSGREF-GYNALTPFHAASTFKLAMNLYLYREVS +RGNLDIEEKLTFLNRHREGGTGILQNNSPGEYSIAQLAGYSIIYSDNVATNILLDRL-DK +NNVKDFMRSLGGQVV--------------DDERNITCPYDLALYMHEILTFS--RQPEGK +LLLNNLFRTEL-KDRIPAPLPREIKVANKIGTWPTNSYHDVAYIAHPRR-PYILVITSKD +TP-GYGATLPVIHHISEMVYEY- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=A0A3B8U214_9FIRM +------------------------------------------------------------ +----------------------------------GSLPDSMINVSDNGAANSLINAV-GM +ESVNEFAAKNGYPATKLNRRMLEWNGT-----ENYTSAADCGKMLEEVLRGQYVSKRASE +RILTALKNQAR-TGKIPAGVPEEIETANKTGELDN-VDNDAAIVWSPSGT-YILCIMSAN +SG--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium sulfidigenes TaxID=318464 RepID=A0A084J7J1_9CLOT +-----KEIKRYLETREGEYSFYFADLKSDYTY-GFNEDLKMVAAGCIKLPIAMAVMKEVE +STNIFLDQLVTITNEDKVSGSGIIHELEGRQYSIKELIVAMLIQSDNTAACKLINTI-GK +DRINSIIHDMGLTSTFIKKYPSGKKED--FDNENITTSYDLCKGLALLSKGKVLNEKHSK +FILEVIRRNQL-TTGISFYWPKDVKTAHKAGSLE-GIENDIVLLNLEKGD-FVFVVMSRN +LPS-NVYGVS------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Jiangella sp. DSM 45060 TaxID=1798224 RepID=A0A1H1XRA1_9ACTN +-----DDIAAALRRAGTDAALHVRPVDGPGEV-ALNPDAVSVAASTYKIAVLLELACQAA +EGTLSLTARQRVPAGRRSLPTGISAMLDDVDLSLRDLALLMMQISDNTATDVVQEVV-GT +DRIAARLKGLGLANTSFPHDCAKLVGSIAGTVGNTTTPRDMTTLVSAIWRDEAGPAAACE +EVRRIMAQQYA-PHRLSTAYRDGPAIAGKTGTFHGGIRNEVGVVDFGGGDRYAVAVYLRQ +HEYDDGAADAVIGEVARLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. M71_S20 TaxID=592872 RepID=UPI000EAD1082 +-----------------------------REV-AVRADEQVVIASIFKVLLVLEFARQVV +AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA +DVLPMLAAELGLPRTRIVGGPRHLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACA +MVRGWMARQIF-WTRLAAGFPPGVRVAGKTGSLP-GLHLEAGVAEYPDGGRYAIAVFVRA +TQTRRIDVDLAMGQAARAAV--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces marokkonensis TaxID=324855 RepID=UPI0011F0E691 +---------------------------DAGEV-AVGADDPVVIASIFKVLLVLEFARQVV +AGQLDPRERVRVTSADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNTAADLLLARV-GL +DTVRLLAAELGLERTRIVGGPRDLLEVLDPRHTTASTPREITRLLRLVWNDAAGPAEACA +LVRDLMGRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVARYPDGASYAIAVFART +RDASRVTVDAAIGRAAGIA---- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. MP36 TaxID=2604468 RepID=A0A5D0UPM4_9ACTN +---------------SGCLHVTVVD-DPAREV-AVRADEQVVIASVFKILLVLEFARQVV +AGQLDPVERVLVRAEDRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DVLPMLAAELDLPRTRIVGGPRQLVEVFDPAHTTSSTARDITRLLRLIWRDEAGPPAACA +LVRELMGRQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAVAVFARS +ERLSTRDVDLAMGEAARVAVE-- +>[subseq from] Putative Beta-lactamase n=1 Tax=Clostridium beijerinckii TaxID=1520 RepID=A0A1S8S319_CLOBE +------EIKRYLESRIGTYSFFFEDLESGFSY-GYNENVQMTSAGCMKLPIAVSIIKHVQ +EGNSTFLDKIKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIDIV-GM +DKINDDIEAQGLKNTKLNRKTSD-ERAVSNGIENITSALDLSKIWKHLYNSSFLDEKNSK +MLMDILQRQQM-KNKLALYIPDDYEISSKTGDKAS-VENDTALIHSPKG-SFTFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. KC606 TaxID=2530379 RepID=A0A4R4U5G5_9ACTN +----RDRIRDIFARAGGSLHVVPVDGPDGREV-AVEADRQTVIASVFKILLVLEFARQAA +AGQLDPTERVVVTAADRLGGWGVAGCADDVEMSLRDLAYLTMSVSDNTAAELLLRRV-GA +DVLPMLAAEMELPRTRIVGGPRQLVEVFDPQRTTSSTARELTRLLSLIWRDQAGPAAACA +TVRELMSRQLF-WTRLASGFPPGVRVASKTGTLP-GLHLDAGVAEYPDGTRYAMAVLVRT +ERLA------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. es.036 TaxID=1761764 RepID=A0A2A9CG90_9BACI +--QVKEKIQECFHGLEGNQSIYVST-PDG-EI-ALHADQPVSSASIIKIAILVEALRQVD +NEQLTIDQVVQIDNVNYVGGAGVINHLSRDYWKLADLLKLMIISSDNTATNQLIDLV-GE +HNINHTMKAAGAFHSKLMRRMMDRD-ALKSGLDNMVSGKDTYLLLREFVTQHLLSQSSME +WGVEVLLQQQF-KDKFPSKISKENLLAHKTGELN-GVEHDAGILFTSNG-PVVYAFLTAG +LL-ENRYGREAIANAGRLLYDFy +>[subseq from] Beta-lactamase n=1 Tax=Bacillus selenatarsenatis SF-1 TaxID=1321606 RepID=A0A0A8X1D0_9BACI +--ELRDRLSNELAGCKGRASLFLEI--EGSII-ESNSNVVYQSASLIKLLILFEALRLIE +AGKLQKDKIVTIKESDKIGDTGVLQAMKVKQLTVEDLLSLMIIVSDNSATNLLIDLI-GI +NSINSAITMIGMKNSILQRKMLDFD-AIQSGHDNFTSAADIALCLKEAVAGGSLNKHSKN +TFFSFLLQQQF-KEKLPFYLDDTLKIGNKTGELP-GVEHDCGIISYGKK-QAFIVVLIDG +LSEP-ESGKTAIRQIGKHV---- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 74 TaxID=1827608 RepID=A0A497W6U4_9ACTN +--------------------------GEAREV-AVGADEPVVIASIFKVLLVLEFARQAA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNAAADLLLDRV-GL +DTVRLLAKELGLDRTRIVGGPRDVLEVLDPLRTNASTPRETSELLRLIWRDEAGAPEACA +HVRDLMSRQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMETGVVRYPDGGCYAVSVFART +REATRPRVDAAIGAAAAMAVD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. AVP053U2 TaxID=1737066 RepID=UPI000780B4C9 +-------------------GAGAWAEPDGREV-GVGADDPVVLASIFKVLLVLEFARQAV +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLSRV-GL +DTVRLLAAELGLERTRIVGGPRDLLEVLDPGHTTASTPREITRLLRLIWTDAAGPPEACA +FVRDLMARQVF-RHRLVSGFPDDVVVAAKTGTLP-GLHMEAGVVRYPDGGCYAIAVFART +HDASRPTVDAAMGRAAETA---- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium tagluense TaxID=360422 RepID=A0A401URD7_9CLOT +-------IKKYLETREGNYSFYFEEINSGYLY-GLNEDKEMVSAGCIKLPLAMSLLKEVQ +NGKIDLQSKIKIESGDKIHSNGIIHEFSGKEYSIVDLLIAMLIQSDNTAANKIIEVL-GM +QRIDELFKDMGLKNTKLKRITTDIKLE-QDELENTTSSFDLSKCFKLLYLKQYLNEENSD +LLIRILKKQQV-TNKLPFYAPKQIQIANKGGSLET-VENDTTLMMIEKGN-FLFTVMANN +LP-NNVYGITTISRVGKMMWD-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02115 TaxID=1703939 RepID=A0A1Q5I198_9ACTN +----------------------------AEEV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL +DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA +QVRELMARQIF-RHRLVSGFPDGVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART +REASRTAVDAAIGATARIAVDH- +>[subseq from] Serine hydrolase n=3 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A355AQL5_9GAMM +-kTLETNLNQLCDEQPFHTGWYIKNLRTGTVL-ERHSNVVVPSASTRKIAIMMAALKAVN +EGEFSLYQPVTMASRFKNNDSGCFQHHSDFSIQLQDALVMMIIVSDNTCTGAVTDLI-GL +ESVNALCQTIGMMDTVHRYGIPGMVGYLPADKTNSTTPADVARLLELILKGVGCTTDLCQ +LAIDILSWQRL-RNRIPARLPLGTKVAHKTGTTAK-NYNDAGIVYTDDEPLFLISAYTDN +VPADHTVAYDLTARLSRLCWDE- +>[subseq from] serine hydrolase n=1 Tax=Devosia sp. FKR38 TaxID=2562312 RepID=UPI0010C12EE2 +----------LLESYPGTLSFCAENLASGARI-SWREDQISATASCIKLFLLVALFAQAE +RGQVSLDERTVVAPGDHVGGSGVLKHSPGVGLSWRDVATLMIVLSDNIATNMVIDQI-GL +EVVNQTIHALGFRQTHLVNRIDFDAIGGDIAKLAVSTAADSVACLKGLAMGTVVSPEASR +AMLDILSRQHY-VDLLPRYLPYDVSVAGKTGFFP-GFRGDIVLLGKGDE-QVVMAAFASG +ADLSFAPENAIARALGEI----- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A2E5Y0J7_9BACT +---LEDNIFSLMKEFDGDVSIYIKHKTQNLEI-GFNENKKMPTASLIKIPIMIKIFDKIK +KGELSLDSTVVYYQDSIGYGEDALSSFKDGEITIKKLLTHMITFSDNHASLWLQKLAGGG +ETINNWLSENNFKNTRVNSRTKGREKDKEKFGWGQTTAKEMVNLITMIRESKVVSKSYSD +KMYRHLTRIYW-DEEALSQIPANFQVASKQGAINR-SRSEVVLVNAPKGD-YAFCIITDN +QTDTDNEGFVLIRKLSKLLWDYf +>[subseq from] Serine hydrolase n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A2G6NYS6_9FIRM +--SLKARLKAEVISFSGKMCFYANDF-KGNVI-AVNANEKFEAASCIKVFILLEFYRQIF +EGKISGNEMLSYGEENAITGSGILRNDVGVTMTAKNFATLMIIISDNIATNIMIDFL-GL +DNINQTIRELGFKSSELHNKID-FEQY---EKLGTTTPRDYGKFFEMLYKEEFWSPEISK +QMLEVFKKQHY-QTMLTKNLPQYIYVASKSGSMD-AARNDGGIIHTPYGA-YVLTIFTKK +FKDP------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. EN16 TaxID=212773 RepID=UPI0008519E02 +------------------------------EV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL +DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA +QVRELMARQAF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART +REASRTAVDAAIGATARIAVDH- +>[subseq from] Beta lactamase n=1 Tax=Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) TaxID=405948 RepID=A4F9H0_SACEN +-------------------GRSGSETGPGREI-GIGADDLVVTASVYKLPLVVALCRAFD +AGRIDPRARVRLNPPSCTPGPTGLATFLDPVVSWRDMAASMIGVSDNTSADVILGEV-GL +DAVAETLAELGLERTRVVGGTADSHAAYDPAYASATTPREMTRLLDLIWSDAVASPQQCA +FIRRLLSNQVW-MHRVRAGFPRGVHVAGKTGTVG-AVRNEVSVVEFEGEVPVAVAVFTLA +ARADLPKVDAAIADCARIAVN-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFCSPHIGHO2_02_FULL_40_13 TaxID=1798384 RepID=A0A1F6A9F8_9BACT +---LLESLADDIQKNGGTFSVYIFDMKANKGF-GINENMVITAASVTKIPILATLYKMAG +EGKIDLEKIIIPQPSDIQNGTGSIRYDPSDTYSIKTLARLMMEKSDNTAAYLFAQIIIKR +SNIQNQVDAWSLTQTDIS--------------DNKTSVYDMNLLLQKIYHGEVTSPALTK +EMLDFMDVSDF-DDRIPKGVDEGVRIYHKTGDDV-GKIHDVGIVDLPKR-PYYLGVMTTD +MT-NAEETKKTIAKISRKVFD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. Ncost-T10-10d TaxID=1839774 RepID=A0A1C5CTR9_9ACTN +---VESRIRTAFDDAEVQGYFFAREIDGDRTI-GVAADEPVCLASVFKIPIALAYAREAA +AGRLDRTERHSVDPHYRDGGIGTSGCADPIEMSLRDLVHMMLTMSDNAATDVVLARV-GL +DTVNGLLAELGLRRTHLVGGCLELTGVCVPERTTRGTARDIAELLVQIWRDEAGPAEACA +EVRAVMSQQIW-PHRLWSGFDDSYRVAGKTGTLP-GWRNEAGVIEDRDGGRWAVAVFTRS +DRPDNSRADRVIGQVAALAVDE- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. AVP053U2 TaxID=1737066 RepID=A0A1D2IA47_9ACTN +-------------------GAGAWAEPDGREV-GVGADDPVVLASIFKVLLVLEFARQAV +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLSRV-GL +DTVRLLAAELGLERTRIVGGPRDLLEVLDPGHTTASTPREITRLLRLIWTDAAGPPEACA +FVRDLMARQVF-RHRLVSGFPDDVVVAAKTGTLP-GLHMEAGVVRYPDGGCYAIAVFART +HDASRPTVDAAMGRAAETA---- +>[subseq from] Serine hydrolase n=1 Tax=Embleya hyalina TaxID=516124 RepID=A0A401Z090_9ACTN +----AQRIRAIFDAARVDGFLHVRDLDTADEV-AYQADDPVVLASVLKVPIVLEYARQAA +DGRLDRAGRHLVTAADREGGIGTDGCMYDVEMSARDLAFMMITQSDNAATDIVLRLV-GR +DNVRATLDALDCRDTSVTGCKDLFESVRDPKRTAATTPREITKLLAAIWRDEAGSTEACA +EVRDIMGRQIW-PHRLASGFADEIRVSGKTGTLW-GVRNEVGVVEYPDGKRYAVGVFLRL +ESFRAPAADASIGLAARAAIDH- +>[subseq from] serine hydrolase n=1 Tax=Virgibacillus sp. YIM 98842 TaxID=2663533 RepID=UPI0013DB6BA4 +-sELKDQITEEIEEISEKVSIYIET-EE-GII-AIHENTKRRAASLIKVPILMEGYRQIE +NKEIHPDTLIYIDQNMRVGGCGVISYLSSGHGSLQNMLELMIIVSDNTATNVLLDKL-QI +DRINKLARSIGCSETVIERMLMDKE-AQAAGLDNYTSAKDMVYLLKTIFENDHYTENSRL +HMLEILANQQF-KHKLPLYAEDGIKFYHKTGELD-GVEHDAAIMEAKGR-ILYAAVLSEN +LF-PNARGQRHISSIGRLLVEY- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. 111WW2 TaxID=1945515 RepID=UPI0010570F93 +------------------------------------------------------------ +---------------------------------------AAARQRHNTATNLPLDLLGGP +TAVTAFASGLDDATTRFDRNEPQLNSTGPDDERDTTTPAAIVESMRAVPLAGGLQPAGRE +RLTTSLVVNTTGDATIRAGVPAGWLIGDRTGTGAQGERNDVGIVLPPDRAPLV------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces lividans TaxID=1916 RepID=UPI0011127D48 +------------------------------------------------------------ +---------------------------------------AAARQRHNTATNLPLDLLGGP +TAVTAFASGLDDATTRFDRNEPQLNSTGPDDERDTTTPAAIVESMRAVPLAGGLQPAGRE +RLTTSLVVNTTGDATIRAGVPAGWLIGDRTGTGAQGERNDVGIVLPPDRAPLV------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora humi TaxID=745366 RepID=A0A1C5ISC4_9ACTN +-----QRVGEIFGRAGLSGCLHVADVDDAREV-AVGADERIVIASVFKILLVLEFARQVA +AGQLDPTERVLVGAADRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DVPSMLAAELGLPGTRIVGGPRHLVEVFDPERTSSSTARELTRLLRLVWRDEAGPPAACA +TVRELMSRQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAVAVLART +ERLDTRDVDLAIGEAARTAVD-- +>[subseq from] Beta-lactamase class A-like protein n=1 Tax=Dethiobacter alkaliphilus AHT 1 TaxID=555088 RepID=C0GGV0_9FIRM +---------------DKRLMFSFYDFATGETL-SHNGDRVIFPASMIKTLYLAVFLEEVK +HERQSLDAEYILQQRDKYAGSTIVYEPSGTKVTHAELLSLMVAESDNVATNIITNIL-GF +QHINDRIKEYGLKNTRAHRKMFDLESD---RPHNLTTLDDLIQLLILIEEQALFDGPLHE +KALDIKRGSSK--CRIGRYAPEDVKVANKLGNTAT-ILADMAIIHFPNREPIALAVMIQG +KNIDDEANAELMGRLSEHIINYy +>[subseq from] serine hydrolase n=1 Tax=Anaerocolumna sp. CBA3638 TaxID=2696063 RepID=UPI001373A0BA +--TLEERIKAELASYNGLMGVYVNDF-KGNKV-EINTEEKFETASCIKTFILGTLFDEVE +KGNKSLTDILTYTKENEIDGSGVLRSLDGVQLTAKNMATLMIIVSDNAATNIMIDYL-GL +ETINNFIKSHGFMDTVLHNKINFVMY----DQLGTTTPKDYGRIFELICKEELISTNASR +QMLEIFKKQHY-NSTLTKSFPQYIYVASKSGSMN-ACRNDGGIISTPYDK-YVIVLFNKN +FTDPDHPATVFSSKVSRLIFDQy +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000370BF08 +------------DRMPSTVSTYLARLDATPTW-TRHPDTTHYAASTMKVAVLVALYRALE +AGRLTPDTAVPVRNEFDSAQPGAAWDRLGGTAPLGWLAERMIVRSSNLATNLLLEQV-GL +PAVADVWARAGARHSSTGRGIEDFAAR-AAGITNPVTAADLAALLRDLALGALATPESCT +AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCSTG +DHPDDEEACQVIADISARAF--- +>[subseq from] Serine hydrolase n=1 Tax=Pedobacter sp. BS3 TaxID=2567937 RepID=A0A5D8YMA2_9SPHI +-kKLQTALEALVKNFHGDVGIYVKNLKTGSIA-AIHANTIFPTASMIKVPIMIGIADKIE +RGELHYNDKLLYRDSLSYNKDDIIGCLADSTIDLSKVQLLSITTSDNTASLWLQQLA-GS +DNINNWLAAHGYEHTRVNSHATGREQYREKYGWGQSTPREMAGLFEQIRNGHVVSPAASE +RMYRNLIRIYW-DGIALSQIPPYIQAASKQGAIN-ASRSETVLVNAPHGD-YVFSVITKN +LQHAANEGWQLIRDVSALLWHYf +>[subseq from] serine hydrolase n=1 Tax=Aminiphilus circumscriptus TaxID=290732 RepID=UPI000478580A +---FEERIRAEIHNFSGLLGLYADDLR-GNVI-ALNADEPFESASCIKVFILAELYRRIA +EGSVAPDQLLSCGEEHFVVGSGILRCLESGVLRVKDFATLMIVVSDNIATNLLIDFL-GI +DAINTTCRALGFPNTVLHNRID-FARF---DKLGTTTPREYGEFFGKIARNELWSAEACE +DMRGMFKDQKY-NTLLTKGLPQYFFVSSKSGSMD-ACRNDGGIVSTPYGN-YVVAIFTKD +FKDSDHESFRFGSRVSRLLFDQ- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A358EEN8_9BACT +--HLAGEVSRLAEHALGTVGVAAYHLETGRWM-TMNGEERFPMASTYKVPIATQILAMVD +QGDLALTDMIEIEQEDVYLTSSAISDLLDDPLSIHNLLELMLQISDNIATDILFEIAGGA +EEITGRMVEVGADGIRVDRTTWALIAAFNADPQDTATPLAMAQLLRK------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces palmae TaxID=1701085 RepID=A0A4Z0G0D7_9ACTN +--------------TGTRLRVHARCVDCGRET-GSAADEPVVLASVVKVLLVLEFARQMA +AGQLDGTERVVVPSAARLGGTGTAGCLDDVRMSLRDLAGFALSVSDNAAADVLFDRV-GV +DTVGLLAAELGLHRTRVVASPSTLLAIRDPLRTNGSTARDMTRLLTLVWTDRAGPPEACA +RLRRLMAHQVN-WHRLAAAFPEEVAVAAKSGTLP-GVRNEIGVVRYPDGGRYAVAVFLET +PAERRADLDRLIGATGHTAV--- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003767360 +------------DRIPGTVSAYLARLDAGPTW-TRHPDTTHYAASTMKMAVLVALYRALE +AERLAPDTAVPVRNEFDSAQPGAAWDRLGGTASLRWLAERMIVRSSNLATNLLLDQV-GL +PAVADVWARAGARHSVTGRGIEDFAAR-TAGITNLVTAADLAALLRDLALGALATPESCA +AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCHTG +DHPDRSADTQLLADVSAHA---- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora deserti TaxID=2070366 RepID=A0A2W2CN06_9ACTN +----TQRIGEIFDRVGVTASLHVVDLDGRREV-AVRADEPVVIASIFKILLVLEFARQVV +AGQLDPRERVLVTAGDRLGGWGVAGCADDAELSLRDLAYFAMSVSDNTAADLLLRRV-GA +DVLPMLATELGLPRTRIVGGPRQLVEVLDPEHTTSSTPREITRLLGLIWRDEAGPAQACA +MVRGWMARQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA +DRTRRIDVDLAMGEAAHA----- +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC401 TaxID=1848324 RepID=A0A5R8P4L2_9ACTN +---------DHARELGADIWLHARDLATGRSV-GVGESTPVVTASVLKVPVALELARQSV +AGEVDLTERITVPPGGVPSPYGLSVQRDDTVISYRDLAHLMIVISDNVATDLVIDRV-GK +DRVAALLAELGLTATAVPQDCAEILAALVPERTCRTTPEEITRLLAGIWRDEAAPPEACA +LVRGWMGDQIW-PHRLTSGFPDDIVISGKTGTLPL-VRNEVGVVEYADGGRYAVGVFTRA +GDPNAPHLDALIGWAAAN----- +>[subseq from] serine hydrolase n=1 Tax=Clostridium beijerinckii TaxID=1520 RepID=UPI000D631CF8 +------EIKRYLESRIGTYAFFFEDLESGFTF-GYNENVQMTSAGCMKLPIAVSVIKYIE +DGKGTFLDKIKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIDMV-GI +DSINEDIIAQGLKNTKLNRRTSDERAA-SSGVENITSALDLAKIWRHLYNSSFLNKKNST +MLMDILQRQQM-KNKLALYIPDDYEISSKTGDKTS-VENDTALIHVQKG-SFTFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Beta-lactamase, putative n=1 Tax=Deinococcus proteolyticus (strain ATCC 35074 / DSM 20540 / JCM 6276 / NBRC 101906 / NCIMB 13154 / VKM Ac-1939 / CCM 2703 / MRP) TaxID=693977 RepID=F0RM06_DEIPM +------------SGFTGTVGLLIQDEAGRDLC-SLNAEAVFPAASLIKLPLLVLGLQAAQ +RGDVALVECLPLPAAEHVPGAGVLHELDAGLLTWRDLLTLMIVVSDNTATNMVIERL-GL +ERVQVALPGLGLTHTRLVGKLQQQNAAQRRGERNQTTPRDMLRLLQNLRQGEYLDASYTA +LALDILGRQQL-RDLMGRRVPCGYPVLSKSGELP-GVHHDAGWLLTP--RPLAVACLSLG +GEDP------------------- +>[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A329TIH4_9FIRM +--TLEKRIAAELYSYQGKMSVFVDDL-QGHTV-EMGADEEFETASTIKAYILAVLYLQAS +RGKASLTEEIEYRPEYFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMVIDYL-GL +DTINACIKELGFAHTVLHNPLH-FDR---YEKLGTTTPRDYASLFAQVAKGTLVSAEASA +EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKD +FH--------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora purpureochromogenes TaxID=47872 RepID=A0A1C5A863_9ACTN +---AEQRVEEIFARVGGSLHVVPVDGPAGREV-AVRADEQTPIASVFKILLVLEFARQVA +AGQLDASERVLVRAGDRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GA +DVLPMLAAELHLPRTRILGGPRQLVEVFDPAHTTSSTAREITRLLGLIWRDEAGPAAACA +TVRELMSRQLF-WTRLASGFPAGVRVAAKTGTLP-GLHLEAGVAEYPDGSRYAMAVFART +DRTRRIDVDLAMGEAARTAV--- +>[subseq from] serine hydrolase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=UPI0007BFA1C6 +-qHVDAALTPLLAATPARISLSLRDLDGGVVL-ARHADRMQPSASIIKVPILLALLEAVA +NGRYALEQPLALPAAERAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLS-GF +DAINQWNQRADLEATRLQRRMMDAAA-REAGRDNYTSAGDATAALCWMLRDGMLPQPLRT +FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVALAVLADG +FT--------------------- +>[subseq from] Beta-lactamase n=1 Tax=Agromyces fucosus TaxID=41985 RepID=A0A4Q2JQH3_9MICO +--ALLRDAAEVLRSAGLRASIVVRDLGSGREL-SIAGDDDYPLASVVKLPLALAVLQRID +EGRLDPARPVTLRPDDRTPLVGYCRFQHPTTVSVEDLLYMAVCLSDDTAADALFDLC-AP +AAVTASLRETGITGITVRHSIRELHRQLDVSSANAGTANACVELLDRIWRAPALAP-QRD +RLRGLLAMNVM-RQRLAPDLEDDAVWHSKTGTFLH-LRHEIGVLEHADGRAIAIAVLSES +SVQRQPAAEQALGLAAKLL---- +>[subseq from] serine hydrolase n=1 Tax=Rummeliibacillus pycnus TaxID=101070 RepID=UPI000C99E755 +-qQFATQCHEIIGQYDAKIGIAILD--GKHTF-YHQEKAIFRAASVMKIPILLTSYLTLS +---KALDTVAVLPEELIVEGAGVIPFLTGNLFTYRNLMELMIIVSDNTASNALLKAI-SM +EKVNQFMQDIGCEDSKIQRYFMDENAV-LKGLDNVTTAKDMIMILQQIGENNFLNEKQQI +DALRIMGNQQF-REMLPSTFDEEIHYYHKTGGLT-GVDHDVAIIQYHEKQ-LYAVVLSQG +-WEDGFTGKKCIAEIGKAIAEY- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. KC213 TaxID=2530378 RepID=A0A4R4R2P9_9ACTN +---VRERIRDIFARATGSLHVVPVDAAEGREV-AVEADRQTVIASVFKILLVLEFARQAA +AGQLDPTERVVVTAADRLGGWGVAGCADDVEMSLRDLAFFTMSVSDNTAAELLLRRV-GA +DVLPMLAAELELPRTRILGSPRQLVEVFDPEQTTSSTARELTRLLSLIWRDQAGPAAACA +TVRELMSRQLF-WTRLASGFPPGVRVASKTGTLP-GLHLDAGVAEYPDGSRYAMAVLVRT +ERLA------------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. rh34 TaxID=2034272 RepID=UPI000BEF5FC7 +-----KRIREVFAGAGAEGLLHAVRVEGDGEV-AVGADESVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAISVSDNSAADLLLARV-GL +DTVRLLAEELGLDSTRVVGGPRDVLEVLDPLRTNAGTPRDITRLLRLVWRDEAGPPEACA +WVRELMGRQAF-RHRLVSGFPDEVAIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART +REASRTAVDAAIGATARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. H-KF8 TaxID=1727216 RepID=A0A1A5P102_9ACTN +---------------------------GGREV-GVGADDPVVIASIFKVLLVLEFARQAA +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLDRV-GL +ETVRLLAAELGLERTRIVGGPRDLLEVLDPRRTTASTPREITRLLRLIWTDAAGPPEACS +LVRDLMSRQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRHPDGECYAVAVFART +HA-LAASRPTVDAAVGRAA---- +>[subseq from] serine hydrolase n=1 Tax=Brachybacterium sp. sponge TaxID=1775432 RepID=UPI0007A4E095 +--------------TEVRIAHCLLD-ADGAVLsAARAEEPFYAASTIKLHVLLAVLRAAE +QGALDLDTELPATRTFTGAGEEFTPTHPEPGIALRDLATRMIDRSSNEATDQLLELV-GL +DAVASVARELGLGATRVERLIGDAA-ALERGQTNETSAADLARTMHHLVAGPGLAADSRE +LALAALRAQTI--PIIATVLRDGVRWGSKSGWVD-GYRHDVAFVEDPAGGPRLLAVMTAG +LAED-EADARITALAA------- +>[subseq from] Beta-lactamase n=1 Tax=Lactobacillus odoratitofui DSM 19909 = JCM 15043 TaxID=1423776 RepID=A0A0R1LSQ4_9LACO +---------------KWTVAVASLDGGHQAYMtNWSPGRAQSSASTIKLFILIRYYQALK +RGLIHANDTYTLRQADKVSGSGILHKKVGTQYTLRQLVTLMIEKSDNIATNVLIDKLGGF +SGVNQTIAKVGTHYTSLERKMMDIS-NISNGKANRINAWEAVQTLLSIYQGQVIDATTDQ +AMLAPMLKTEN-RTKLPAQLPEGAVCWNKSGESNRGIENDMAIIKYQGH-VFAVAALIEL +DGATQEQTDSQVAAIAR------ +>[subseq from] serine hydrolase n=1 Tax=Streptomyces kaniharaensis TaxID=212423 RepID=UPI001296EEF8 +---------------------HARDLDTGADI-ALGADTLVSTASVHKLCLLVTLFREAA +AGRIDLTRQLDIPAAGRTAGQTGLAAMLDAALSLRDLAYLTAAVSDNAAADVLWDEV-GL +DAVNRTMAELGLTRTVAVHGFRDLIAVLDPTFTNRSTAREMTALLAALWSGEACPGEPGT +ALRRLLGLQVW-PHRLAAGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA +AATSLPAADAAIGTAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Desulfallas geothermicus TaxID=39060 RepID=UPI000B809644 +--PLQEQVVAYLARQPGTYGLYFIDLNSGREF-GYNALTPFHAASTFKLAMNLYLYREVS +RGNLDIEEKLTFLNRHREGGTGILQNNSPGEYSIAQLAGYSIIYSDNVATNILLDRL-DK +NNVKDFMRSLGGQVV--------------DDERNITCPYDLALYMHEILTFS--RQPEGK +LLLNNLFRTEL-KDRIPAPLPREIKVANKIGTWPTNSYHDVAYIAHPRR-PYILVITSKD +TP-GYGATLPVIHHISEMVYEY- +>[subseq from] Beta-lactamase regulatory protein BlaB n=2 Tax=Amycolatopsis TaxID=1813 RepID=A0A178XF32_9PSEU +-----ETIVRRAEEVGVEVRLHAAEIDGTRGL-GIGEDVAVVPASVFKVPIALELARQAA +EGALDLGARITVKPGHPTPPYGLATFRHEVQMSWHDLAILMIGISDNVATDLILAEV-GK +AAVNDTLRRLGFTRTVVPQDCGELLAALQPEKSCRTTAAEMTRLLGLIWRDEAAAPEACA +DVRRWMELQVW-PHRLRSGFPDRVRTSGKTGTLP-AVRNEVGVVEYPDGGRYSVAVFTRA +GDSRVPERDTFIGFAAATAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. KC721 TaxID=2530380 RepID=A0A4R4LLI7_9ACTN +---VRERIRDIFARATGSLHVVPVDAAEGREV-AVDADRQTVIASVFKILLVLEFARQAA +AGQLDPTERVVVTAADRLGGWGVAGCADDVEMSLRDLAFFTMSVSDNTAAELLLRRV-GA +DVLPMLAAELELPRTRILGSPRQLVEVFDPEQTTSSTARELTRLLSLIWRDQAGPAAACA +TVRELMSRQLF-WTRLASGFPPGVRVASKTGTLP-GLHLDAGVAEYPDGSRYAMAVLVRT +ERLA------------------- +>[subseq from] Serine hydrolase n=1 Tax=SAR202 cluster bacterium TaxID=2030829 RepID=A0A5N9CK39_9CHLR +--ELINRMNAMCLESPFQSGWYLKNLQTNESA-NYYGDVVVPSASTRKIAILMNAMKWIH +EGKLSLDQPIRIDETQYVGNSSGCFQYLRPGVQLYDVLTMMIIVSDNTSTGIVANLL-GL +DSINEFSQSIGMIGTTHRHKLPPLDLDHSLDYTNSTTPNDVGLILELILLGTGSSKELCQ +IALDILLNQKL-NNKLPALLPKGTKVAHKTGTGAR-NYNDAGIIFLEDSPLFILTVFTEN +VPTSLADG--------------- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus odoratitofui TaxID=480930 RepID=UPI0007051717 +---------------KWTVAVASLDGGHQAYMtNWSPGRAQSSASTIKLFILIRYYQALK +RGLIHANDTYTLRQADKVSGSGILHKKVGTQYTLRQLVTLMIEKSDNIATNVLIDKLGGF +SGVNQTIAKVGTHYTSLERKMMDIS-NISNGKANRINAWEAVQTLLSIYQGQVIDATTDQ +AMLAPMLKTEN-RTKLPAQLPEGAVCWNKSGESNRGIENDMAIIKYQGH-VFAVAALIEL +DGATQEQTDSQVAAIAR------ +>[subseq from] Beta-lactamase enzyme family n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KWF2_9BACT +------------------------------------------------------------ +-----------------------------------------MQESDNNACDILFSLIGGP +AAVQKDLKEWGVENMNVKYTEADTHRNHEWQYSNSARPSAVTFLFRMFDEGKILKKDTQL +FLWDMMASCATGAERLKGLLPKEYVVAHKTGTGGVSAINDAGIIVLPGGRRMAVTVFVMN +SKDSPAVCEGTIASVARWLCTEw +>[subseq from] Beta-lactamase n=1 Tax=Clostridium putrefaciens TaxID=99675 RepID=A0A381J6C6_9CLOT +-----KEIKKYLESRIGDYSFYFEDLDGGYIY-GYNENVCMVSAGCVKLPIAMAILKESE +IGNISLNDKLTVSIDDKVSGNGIIHEFGEKEYTLIELLIAMLIQSDNTATNKLVDLV-GM +SKINSIFKEMDLKSTKLNRRVEKEK-DVDSTIQNITSSYDLCLCWKHLYNSTYLSKENSS +WVIRIMKKQQM-KNKLAFYIGEEANIANKTGDLT-GVENDTSFIQMPKGN-FAFTMMSKG +VPND-VYGIVTLAKSGKMMW--- +>[subseq from] Bata-lactamase n=1 Tax=uncultured bacterium BAC AB649/1850 TaxID=1037453 RepID=F6K0V6_9BACT +--DLEDDLTRVFADADVDVWLHVRDVGTGRQV-ASRADEQVVIASLVKILLVLEFARQVA +GGRLDPRERVLIRAADRLGGWGTAGCADDVEVSLRDLAYFAMSVSDNTAADLLLKRV-GP +DVLPVLAEELGLARTRIVGGPRQLLEAFDPAHTTSSTAAEITGLIAKIWCDDAGPAAACA +MVRDLMAQQVF-RTRLVSGFAPSVRVSAKTGTLP-GLHMEAGMIEYPDGRRYAAAVFART +RRTHRIDVDLAIGRAARRAVD-- +>[subseq from] serine hydrolase n=1 Tax=Acidobacteriaceae bacterium KBS 83 TaxID=1267533 RepID=UPI000364D718 +---LQSQVERIASEHHGQVSVYAKGLKTGQTV-AMKADEPVQTASVIKLAILYEAMEQIR +AGKAHWDDRVTLTKENQTGGSGVLGFFDTPTLTLKDVLSMMVITSDNTATNVAIDKI-GL +DAVNAEMGRLGLKNTWLYKKVGKPPSDQKKFGLGKTTAREMATLMERIVTNDAPPTDADH +AICNVMLRSQFYRDGVPRYLEEGSAIANKTGALDE-VRNDVDAVATKNG-LLILSIFTWD +NKTDDNEAYLTTAKIAKAIVGTw +>[subseq from] Serine hydrolase n=1 Tax=Gordonia lacunae TaxID=417102 RepID=A0A2C9ZK99_9ACTN +-------VREIFADAGCSGRVHVRTIGTPVEY-CHDADTPVVLASVYKLAVLISLCRMAD +RGDIDLAASITVDPTRWAQGPTGLALFMDPVTSWRDLATSMMTVSDNVAADVILSQV-GL +PRIHDDLVELGLMNTRIVGGVAELHEAYDAAYSSSATPRDCTTLLDAIWTDRAASAPSCE +FIRQTMRKQVC-TSRLASGFPRRVSVAGKTGTLV-AVRNEVGVIEFPGELPVAVAVFTTS +ARSELPEVDRAIGEVARVAVT-- +>[subseq from] LigA n=1 Tax=Nocardioidaceae bacterium Broad-1 TaxID=408672 RepID=E9V0D9_9ACTN +----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD +RGLVSLDEPIAVHPDSAVTQDPVTWEAVGSQLPLGDLVRRSLTVSGNLAVNLVLERV-GL +EEVAAVLADAGVTMTTIARGIEDAPA-REAGLQNLVTANDMGKLLTKLASGRLLSPESTA +EIEGILVAQEY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIRPAQGEPQVMVVLTTG +LDD--DESEFRISEVARYLWS-- +>[subseq from] serine hydrolase n=1 Tax=unclassified Microbacterium TaxID=2609290 RepID=UPI00068B4FB1 +-------------------------VADGPEV-TVGADDPVVLASVFKILVLTAYVRAVA +AGELDPTARTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDVIYHRL-GT +EAVDRVIADLGLADTRLIGCCEDLFAAVQPLRTSHSTPRDVTTLLNALWTDTAAPAEACR +QARDIMALQIW-PHRLTAGFPGEVRIAAKTGTLPT-WRNEAGVVTYPDGRRYAVAVFTRA +ASL-ADRQPLVDASIGRAAF--- +>[subseq from] DNA-binding transcriptional LysR family regulator n=1 Tax=Propionibacteriaceae bacterium ES.041 TaxID=1945889 RepID=A0A2A9GTU8_9ACTN +----VAQIRDVWRAVGVVGGLHARDLRSGAML-AVDADDAWPMASVAKVPLGIALHRAAD +AGLLGLDQALTLRPDGRTSGTTGISAMADPVLSLRDALYLALTISDNAAADAIWDTL-GA +DRVQHLLRQLPPDQVRLGEATRDLYDSLDGPYACRATAAGATRMLELIWSDQAASPAACA +AIRDLMRRQVW-AHRLASGFPADLDVAGKTGTAGD-HRHEIGVVSYPDGRRYAVAVFTRL +QQETPHHRDWAIGETARLAVN-- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB00072 TaxID=1703928 RepID=A0A1Q4ZY10_9ACTN +---------------------------DAGEV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL +DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGQPEACA +QVRELMARQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART +RQASRTAVDSAIGATARIAVDH- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridium celatum DSM 1785 TaxID=545697 RepID=L1QEQ5_9CLOT +-----KEIKKYLESRIGKYSFFFEDLKSGYVY-GYNENVSMVAAGCMKLPIAVSLIKAVE +DKKVDFMDKIKIQSSDKVFGTGIIHEFNEREYTVFELLVIMLIQSDNTAANKIIDIV-GM +EQINEDILAMGLKNTKLNRKTNDERINV-EGVENFTSAYDLSRIWKHLANGTFLNKENGQ +MLIDILRRQQI-KNKIALYIPDDVEISSKTGDKK-GVENDTALLELPKGR-FAFTVLSQD +VPNS-VYGTVSLAKCGKMMWD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Clostridium saccharoperbutylacetonicum N1-4(HMT) TaxID=931276 RepID=M1MJ40_9CLOT +------EVKRYLESRIGTYAFFFEDLESGFSY-GYNENVQMTAAGCMKLPISVSVLKYVE +DGKIDFLDKIKIEEADKVYGTGILHEFDNREYTVFELLVAMLIQSDNTAANKLIDIV-GI +DRINDDIEAQGLKNTKLNRRTSDERAA-SNGIENITSALDLAKIWKHLFNSSFLNEKNSI +MLMDILRRQQM-KNKLALYIPDDYEISSKTGDKAN-VENDTALIHTHKG-SFTFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Serine hydrolase n=1 Tax=Megasphaera sp. AM44-1BH TaxID=2292358 RepID=A0A413R399_9FIRM +----------------TDLSVYCRPLDREEPV--VYHERVLPSASLIKLPVMSAFFRKEK +EGAVSFSENLRITSP--VE-GGSYYKWGGAMATISELIFHMIVESDNTCTNVLIDRL-GM +EAVNEEIRCLGLTHTVMQRKMMDFNAS-RDGRENMTTVSDMGRFFSLLSEGRAVDAVRDQ +RMLDILSQQED-NCILPAQLPHTVRVDHKTGELD-GIYHDCGLIYAPSR-PFIFCLMADG +VS--------------------- +>[subseq from] D-alanyl-D-alanine carboxypeptidase family protein n=1 Tax=Clostridium argentinense CDC 2741 TaxID=1418104 RepID=A0A0C1U717_9CLOT +-----KEIKRYLDNRDGIYSFYFEDLKSGYTY-GLNENVQMTAAGCIKVPIAMALMKEIE +NNNFNIDDKVSITKNDMVSKYSIIHEFSEKEYTIKELLIAMLIQSDNTAACKIVNLV-GM +DRINELIKDMKLYSTEVRKYPSEN--KIDDNKENVTTSHDLSKCLRLLSNNSYLNEEHSS +LILETLKKNQV-NTGIPFYLPHESTTANKIGTLKC-VENDTALLNLPKGN-FVFTVMSSN +LP-SNVYGLTTISRIGKMMFD-- +>[subseq from] Peptidoglycan-binding protein n=1 Tax=Thermoanaerobacterium sp. PSU-2 TaxID=1930849 RepID=A0A1X2FVK4_9FIRM +-qELKENIETLLSQHTGNYGVYFIDLNSGETF-DINGYGSFIAASTYKVPLNFYVYTLIT +EGKLDPNMEVQYTSQDYEGGSGSIQYDPVGTYTIRELSKKSIEESDNIASNMLMRVV-GY +DNYLNFIESLGAYVVPY--------------SDNVTSPRDLSIYMEDILNYANAHSSTAG +ELLSYLENTIY-NDRISYPLPSNITVAHKIGNLSN-VVNDTAIVFYTQK-PYILTIMGNN +VDSDNSDAYTVIREISKMVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. DH-12 TaxID=2072509 RepID=A0A2K2RSM9_9ACTN +----------------------------TAAV-TIDADEAVLMGSVYKMPLAVAYCRQVD +AGVLDPRQRVILSPQDRLPPTGISQLSDEVSMSLRDLVVMMMSISDNAAADAVLHHV-GA +AAFDDACQALGLFRTQLSDGAAGTLAVYDPAWATSTTPTEIARLLHAIWTDEAASPANCA +FIRRTMGLQPW-QHRLSAGFPDDVSVSGKTGTFGV-MRHEAGVVELADGRTYTAVVFTQA +ARADLPRADAVIGATARAAVEH- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. CB01531 TaxID=1718947 RepID=A0A1Q5D0Z5_9ACTN +-----EQVGAIFERAGISGSLHVTDVDDGSRQvAVRADDQVVIASVFKILLVLEFARQAV +AGQLDPVERVLVRAADRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRI-GP +DVLPMLAAELDLPRTRIVGGPRQLVEVFDPTHTTSSTAREMTRLLGLIWRDEAGPPAACA +LVRELMGRQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAVAVFART +ERLSNIDVDLAMGEAARVAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Mycobacterium sp. Root265 TaxID=1736504 RepID=A0A0Q8ZND6_9MYCO +--------------------------GTGRVI-DIDGDAPVVAASVYKVVVLIAAARAFD +TGRLDPHATVRVVPGDCTPGPTGISLFADPVLSWLDLARMMITLSDNAAADVLLAAV-GM +DALHDVIDDLGLASTRVVGGTAALQRAFDPAYTTATSPADTNTMLTAIWTGTAASPESTH +AMKTILSQQIW-PHRIRSAFPPDVVVAGKTGTIGP-IRNEVAVVSFPDEIPIAVSVFTRA +ARSDLPVVDQAIGSAARLAVN-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium thiosulfatireducens TaxID=150336 RepID=UPI0012433B30 +-----KEIKRYLETREGEYSFYFADLKSDYTY-GFNEDLKMVAAGCIKLPIAMAVMKEVE +STNIFLDQLVTITNDDKVSGSGIIHELEGRQYSIKELIVAMLIQSDNTAACKLINTI-GK +DRINSIIHDMGLTSTFIKKYPSGEKED--FDNENITTSYDLCKGLALLSKGKVLNEEHSK +FILEVIRRNQL-TTGISFYWPKDVKTAHKAGSLE-GIENDIVLLNSEKGD-FVFVVMSRN +LPS-NVYGVS------------- +>[subseq from] serine hydrolase n=1 Tax=Mucilaginibacter sp. HMF7856 TaxID=2682091 RepID=UPI0012F7C8F7 +-kRLTSKLQEAVQGYNGDIGIYVHNLKTGKTAtSANADTLFPTASMVKVSILCGVMDKIE +KRELQYNQKLVYNDSLLYKGEDILGSFKNGDIQLSKVTMLMITMSDNTASLWLQRLV-GT +PYINNWLNQNGFKSYRDNSRDPARQEWRAKYGWGVSTPYEMCRIFQMIRERRAISPAASE +RMYRTLNRIYW-DDKALSEIPPYVQCISKQGAVDQ-AKSETVLVNAPHGD-YVFSVMTNN +IKTDDNETAVMIRKISALLWHYy +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora echinofusca TaxID=47858 RepID=A0A1C5GGD8_9ACTN +---------------------------GRREV-ALRADEQVVIASIFKVLLVLEFARQVV +AGQLDPRERVLVTAADRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA +DVLPMLAAELGLPRTRIVGGPRQLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACG +MVRGWMARQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVVEYPDGGRYAVAVFVRA +SQTRRIDVDLAMGQAARTAV--- +>[subseq from] Serine hydrolase n=1 Tax=Selenomonas sp. mPRGC5 TaxID=2593411 RepID=A0A5D6W8X2_9FIRM +--DLSRNIERILGADSSRYAIYFWRPAEEEEP-FIYQNRPMSPASMVKVFVMAAAMQEVH +DGRLSLDEKLVIREADVVGGAGVITWNIGEARSVRELVSGMITNSDNTATNMLIDRL-GM +DKINRYIAAHGYGDTKLVHKMMIGN----GGRKNFSSVRDLGKLFSRLYYHQLVGENEDR +FMELVLSGQKD-KECFNAALP-DFNIAHKTGEVT-GLYDDGGIFFGKQGD-FVLVIMDEG +I---------------------- +>[subseq from] Serine hydrolase n=1 Tax=Nocardia terpenica TaxID=455432 RepID=A0A291RHP7_9NOCA +---------EIFEQAGVQGWLHARCLDCGAEI-GDGADEPVVLSSVVKVLLVLELGRQIA +AGQVDPTDRVRATAAYRLGGPGTSGCRDDVEYSLRDAAYLALSLSDNTAADLLFERV-GL +DNVRSLARELGLTRTRIAGALRDLLLALDPRRTTASTPREMTRLLALIARDAAGPPATCT +WLRELMSLQLN-QHRLASAFPSNALVWGKTGTLP-GLRNEIGVVEFPDGARYAVAVFTKA +RVHRLPQADRAIGTAARTAIE-- +>[subseq from] Serine hydrolase n=4 Tax=Clostridium TaxID=1485 RepID=A0A0B5Q9V0_CLOBE +------EIKRYLESRIGTYSFFFEDLESGFSY-GYNENVQMTSAGCMKLPIAVSIIKHVQ +EGNSTFLDKIKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIDIV-GI +DKINDDIEAQGLKNTKLNRKTSD-ERAVSNGIENITSALDLSKIWKHLYNSSFLDEKNSK +MLMDILQRQQM-KNKLALYIPDDYEISSKTGDKAS-VENDTALIHSPKG-SFTFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Serine hydrolase n=1 Tax=Haladaptatus sp. W1 TaxID=1897478 RepID=A0A1D2QGE5_9EURY +-dELAATIAAYDETIDGNLGVFLGFPSGPDVVcSHDETRVFQSASTVKLPVLYALYERYD +ARLDELDRSCPLSLENRVGGSGLLH-LLDATPTVEDLARAMISVSDNAATNQLIDHL-GM +SAVNDAAARLGMDRTRLARKMMTMLEVPADEPTNATAPLDCARFFADLVCETTLSAAAYE +RMRVPLAAQKD-TSMVPRYLPYQTDVAHKTGRLPT-AVLDTGFLSVPDRRPLVFSVFIDG +VSGTETDGARATSDTGADA---- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536S7A1_9CHLR +--DLVQQLDGLVSAFPGGTGLWIADPNLPAPLfKHAPEEQVITASLYKLGVLAEAERRVD +SGELHYSDPVTIEPEDVTEDGSFED--SGVSLTLDEALEAMITISDNGAALALWHIL-GG +SNIDATLTKAGM---------PDFHVAFDDSEDNVATPHAIGTFFTLLAKRQLISPAASD +RMLARLERQQI-NNRLPAQLPPGVVVAHKTGNLA-GLTHDAGIIYTKSGP-RVVVAMTWD +AS--DDEADNFISSVGALVYS-- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=A0A330LFP3_LACSK +------------------------------------------------------------ +------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM +TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNLLYQNR--DQAPYS +KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ +VQNPAAERQA-IGA--------- +>[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. TaxID=1882438 RepID=A0A3C1BJH6_9SPHI +-kELTARLQDDIKGFNGQAGIYVHNLKTGKTA-AINADTLFPTASMIKVSIQCGLMDKIE +KGEMQYNQKLVYRDSLLYKGEDILGSFKDKDIEVSKVALLMITMSDNTASLWLQKLV-GA +DYLNHWLDVNGFKVMRDNSKATGRGAMHAKYGWGVTTPYEMCRLFTIIRNGEAVSAAASE +RMIRNLGRIFW-DNIALSQIPPYIHTISKQGALDD-YRSETVLVNAPHGD-YVFSVITNN +NKTQDNEADVLIRKVSALLWHYf +>[subseq from] serine hydrolase n=1 Tax=Brevibacterium casei TaxID=33889 RepID=UPI0011A1E2A3 +-----DEINGVWTSLGAQGFLFAEDLETHRSV-GIRESARIPLASVGKVAIVAGLLDAAA +DGVLDLTRRVVVDPTTATPGTGISGLYDPVEMSLRDLAAMALSVSDNAAADTLFALV-GP +ERITALLHRFGIRSFDVVAPMSHLYDQLPDSAFNTGTVRATARLFELIHTGRLLGTEDSA +VLRDLLRRQIF-RHRIAAGFPDAVSYYGKTGTFLN-FRHEAGVIVDSDGTAYSIAIFTRS +TIATQPELDASIGYCARLAIEH- +>[subseq from] serine hydrolase n=1 Tax=Nocardioides sp. SAI-095 TaxID=2597743 RepID=UPI001358C529 +----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD +RGLLSLDEPITVHPDAVVGQDPETWAAVGSPLPLGDLVRRSLTVSGNLAVNLVLERV-GL +EEVAAVLADAGVTMTTVSRGIEDAPA-REAGLQNLVTANDMGKLLTKLASGRLLSPESTA +ELEGILVAQEY-RDAIPLGVPEDAVVGNKTGWID-GVRHDMAIIRPAQGEPQVMVVLTTG +LDD--DESEFRISEVARYLWS-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora violae TaxID=1278207 RepID=A0A4Q7UMU9_9ACTN +-----------------------------REV-GVRADEQAVIASIFKILLVLEFARQVE +AGQLDPTERVVVTAADRLGGWGLAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLTRTRLLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA +EQPRRIDVDLAMGEAARTAV--- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. AMSO31t TaxID=2650566 RepID=UPI00124B297D +------RIGEIFRRAGISGCLHVEDVDPGREV-TLRADEQVVIASVFKILLVLEFARQAV +AGQLDPVERVLVGAADRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEHTTSSTAREMTRLLGLIWRDEAGPPAACA +MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVVEYPDGGRYAVAIYART +ERLSTRDVDLAMGEAARAAVE-- +>[subseq from] PEGA domain-containing protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535R352_9CHLR +------GLDAYLRSTGGQFGIYFLDLKTGSEF-GYHQDDLMEAASDIKIPVALYVFHQVE +ANAVKWDDKVTLEAEDFMGGTGLLQGSASAGFSYWDLLTLLIEQSDNTAWRTLQRVL-GA +DTIDAYAASIGAPD---------CHQV-----DDNCTAHESGLMLARLYRGQLLNRADTA +TLLTVFESTVF-DDRINYYLG-GLTVAHKTGADG-GVMNDVGIVYAAGG-PFLVSVYSQT +GGGT----VQPIRDVARAAYRYf +>[subseq from] Beta-lactamase class A n=1 Tax=Plantactinospora sp. CNZ320 TaxID=2035246 RepID=A0A2N3S418_9ACTN +----------IFDRVGVNACVHVVDVDNGREV-GTRADEQVVLASVFKILLVLEFARQVV +AGQVDPTERVLVGAGDRLGGWGTAGCADDVELSLRDLAYFTMSVSDNTAADLLLRRV-GR +DVVPLLAAELGLARTRVIGGPRQVLEVFDPAHTTSSTAREITRLLTLIWRDEAGPPAACG +MVRDLMSRQMF-WTRLPSGFPPEVRVAAKTGTLP-GLHIEAGVAEYPDGGRYAIAVFAQT +QRLSTRDVDLAMGEVAHAAV--- +>[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. TPD7012 TaxID=2171975 RepID=A0A2T7X1Q1_9MICO +------------------LHAAEIGVVDGPEV-SVRADEPVVLASVFKILVLTAYVRAVE +SGELDPVGRTTVTSRYRIGGVGTAGFSDDVEASWRDLALNMMSMSDNAATDVIYHRV-GA +EAVRQVITDLGLEGTHLVGCCEELFDVLEPARTSASTPREVTTLLNALWTDTAAPAAASA +AAREIMAQQIW-PHRLSSGFPSEVKIAAKTGTVP-AWRNEAGVVTYPDGRQYAVAVFTRA +DSL-AERLPAVDASIGRAAC--- +>[subseq from] serine hydrolase n=1 Tax=Plantactinospora sp. CNZ320 TaxID=2035246 RepID=UPI000C6F20AC +----------IFDRVGVNACVHVVDVDNGREV-GTRADEQVVLASVFKILLVLEFARQVV +AGQVDPTERVLVGAGDRLGGWGTAGCADDVELSLRDLAYFTMSVSDNTAADLLLRRV-GR +DVVPLLAAELGLARTRVIGGPRQVLEVFDPAHTTSSTAREITRLLTLIWRDEAGPPAACG +MVRDLMSRQMF-WTRLPSGFPPEVRVAAKTGTLP-GLHIEAGVAEYPDGGRYAIAVFAQT +QRLSTRDVDLAMGEVAHAAV--- +>[subseq from] serine hydrolase n=1 Tax=Kocuria salsicia TaxID=664639 RepID=UPI0012EDAA72 +-------VTGILRDATGAVAVRVIDAPELPAF-GWRADEAFPAASLYKLVVMVAFCRAVD +RGELDPTALVTLRPEDRADPTGLAICQDPVRISWRDLVRLMMTVSDNAAGQAVLREV-GH +ARVRDVLRELGLSSTVIRPGAPDAVPGYDPLLVSATTASDLVALLRAIWQDRAASAAQCA +FMREVMSQQAWGHRFAEAFSYPGAGVAAKTGSFG-ALCHEAGVISHPGEKSIAVAVLTRS +VRRQIAVSNRIVGQIARHCVRSy +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces glauciniger TaxID=235986 RepID=A0A239M6A8_9ACTN +--------------------------GEAAEV-AVDADESVVLASVVKILPVLEFARQVA +AGQLDPRERVRIAAADRLGGWGTAGCADDVELSLRDLAHFAMSVSDNTAADLLLARV-GL +DTVRLLAEELGLTGIRIVGGPRDVLEVLDPARTNAGTPREITRLLRLIWRDEAGPPQACA +WVRELMGRQVF-RHRMVSGFPDEVTVAAKTGTLP-GLHAEAGVVAHPDGGRYAVAVFART +REATRPAVDSAIGAATRISV--- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis albispora TaxID=1804986 RepID=A0A344LM32_9PSEU +--------------AGVRGWLHARRLGAEAEC-GWDADEPVVLASVVKVPLVLEFARQVA +AGQLDPRDRVRIGARDRLGGTGTAGCADDVELSLRDAAYFAMTVSDNTAADVLCDRV-GL +DNVRSLVRELGLVRTRIAGAPRDIVAALDPGWTNASTPREMTALLEHLWSEP---GEAAA +RVRQWMGQQVF-WSRLGGAFGPEVRVSGKTGTLPC-IRNEIGVVEYPDGTRFAVAVFTRS +ASQRQPAIEQAIGAAAAAAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Tamaricihabitans halophyticus TaxID=1262583 RepID=A0A4R2QWX1_9PSEU +--RLTRELNAHASTGDGQWHFSVWE--HGSPVvSLNGAVPVTAASTIKVPLLVVALQDVA +AGRRSLNDEVAIPV-ERVGGAGVLRLLPSVTLSLAEALTLMIVVSDNVATNAVIDLF-GV +ADTDQRITTLGLRGTRLRRRLMDQDAA-MAGLENVTTADDQAALLDRLAGAELLPDRLRE +FALDALGEQQV-NDRMPVRLAEDVRCLHKTGELH-GVRHDVGLLVFDDRM-VSLAALGTG +LTSP------------------- +>[subseq from] Serine hydrolase n=1 Tax=Kribbella sp. NEAU-THZ 27 TaxID=2575441 RepID=A0A4U3LZ67_9ACTN +----NARIRAVFEDAGVRGWLHAVALDEPESTvEVDADGIVPLASVYKLPLLAGFCRLVD +LGEIDPREQLTLDPSTKTGGPTGLSTFADPVASLRDLALSMMTLSDNASADALLDVV-GL +RRLAELLESFGLHRTRVRRGTADLQRVYEAANASASSARDLTLLLRRLWAGELLSPEQTE +FVKVTMHRQVF-LHRLASGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGTAYAIAVFTLA +ARGDQPRVDAAIGEAARVAVD-- +>[subseq from] serine hydrolase n=1 Tax=Veillonella sp. VA142 TaxID=741834 RepID=UPI000F8D9020 +---------------------------HNESI--VKQSKPVRAASMIKVYILGYLFEEIE +AGHIDLGETIELEESDKVGGAGILSGAVGTKLTVDELAKLMITVSDNSATNILIHRL-GM +GSINQYVLKNGFIDTKLQRYMMDLE-AIRQGRENYTSAKDLGNWFMNLLEGKGMSNSSRE +KMLMYLLGQTD-TETFNEALS-NRLIAHKTGELA-GVYHDGGIIFQSKGEAYILITLSD- +----------------------- +>[subseq from] Putative beta-lactamase-like protein n=1 Tax=Thermacetogenium phaeum (strain ATCC BAA-254 / DSM 12270 / PB) TaxID=1089553 RepID=K4LID4_THEPS +--ELRKELADHLKTLPGTYGVYFKDLASGEEF-GINERVPIPPASAIKLPVVLYLYEQVA +KGELDWNDRVRYRKSDYQDGAGDLQFTARDGYSLRCLATISMVISDNIAHNMLVRHL-GY +DNVMNFIRRLGPDTTRPF------GSA-------STTARDMGAFLEELIDFASREPEQGA +RLLNDLAHTVY-HVGLPGKLPPKLVVSHKEGSIN-GVATDVGIVFS--RRPYILVVLSKG +IP-DEDTGFRNIAEISRIVYNY- +>[subseq from] serine hydrolase n=1 Tax=Microbacterium sp. K27 TaxID=2305445 RepID=UPI00109BE9E8 +-------------------------VADGPEV-TVGADDPVVLASVFKILVLTAYVRAVA +AGELDPTARTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDVIYHRL-GT +EAVDRVIADLGLADTRLIGCCEDLFAAVQPLRTSHSTPRDVTTLLNALWTDTAAAAEACR +QARDIMALQIW-PHRLTAGFPGEVRIAAKTGTLPT-WRNEAGVVTYPDGRRYAVAVFTRA +ASL-ADRQPLVDASIGRAAF--- +>[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. Root322 TaxID=1736514 RepID=A0A0Q6PD28_9MICO +---------------------------VGPEV-TFGADEPVVLASVFKILVLTAFVRAVA +AGELDPTERTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDIIYHRL-GG +EAVNRVITDLGLRSTRLIGCCEDLFAVVQPLRTSHSTPRDVTTLLNALWTDTAAPAEACR +QARDIMALQIW-PHRLTAAFPGDVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTQA +ASLV-DRQPLVDASIGRAA---- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI0009B8ACE0 +--TTDEQLRAVFADAGCRGWVRAERIDTGTAV-DYEGDDPVVAASVWKIVLLVAAARAFD +EGSLTATDSVRLVPAQCSPPTGISSFADPVTMSWRDIARSMITVSDNAAADAFLGAV-GL +DALTRVIDDLELEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRAIWLGTAASPAQCG +YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA +ARMDLPLVDQAIGHAARIAV--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. NEAU-D10 TaxID=2293571 RepID=A0A371Q7S3_9ACTN +---AEARIREAFDAAGVEGFFFAREIDGARTI-GVAADEPVCLASVFKIPIALAYAREAA +AGRLGRTERHAVDPRYRDGGIGTSGCTDPIEMSLRDLVHMMMTLSDNAATDVVLARV-GL +DTVNAMLAELGRNKTHLTGGCLDLIGVCVPERTTRGTARDTAELLAGIWRDEAGPAEACA +EVRTVMSQQIW-PHRLASGFDDSYRLAGKTGTLP-GWRNEVGVIEDPDGGRWAVAVFTRC +DRPDNPRADRVIGQVAALAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Agromyces sp. OV568 TaxID=2135465 RepID=A0A3E0I6F7_9MICO +--ALLRDAAEVLRSAGLRASIVVRDLGSGREL-SIAGDDDYPLASVVKLPLALAVLQRID +EGRLDPARPVTLRPDDRTPLVGYCRFQHPTTVSVEDLLYMAVCLSDDTAADALFDLC-AP +AAVTASLRETGITGITVRHSIRELHRQLDVSSANAGTANACVELLDRIWRSPALAP-QRD +RLRGLLAINVM-RQRLAPDLEDDAVWHSKTGTFLH-LRHEIGVLEHADGRAIAIAVLSES +SVQRQPAAEQALGLAAKLL---- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. Ag82_O1-15 TaxID=1938855 RepID=A0A2A3J362_9ACTN +--------------------------GEAREV-AVGADEPVVIASIFKVLLVLEFARQAA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNAAADLLLDRV-GL +DTVRLLAKELGLDRTRIVGGPRDVLEVLDPLRTNASTPRETSELLRLIWRDEAGAPEACS +HVRDLMSRQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMETGVVRYPDGGCYAVSVFART +REATRPRVDAAIGAAAAMAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. CUA-806 TaxID=1517936 RepID=A0A1Q9U2V8_9NOCA +----EDQIVEVFHDAGCRGWLHAQRIDAGPTV-DVNGHEPVVAASVYKVVVLVAAARAFD +SGRLDSHTQVRVVPSDCTPGPTGISTFTDPVLSWLDLVRSMITVSDNAAADILLAAL-GF +GIVEQVIVDFGLSSTRIVGGTAALQGAYDPAYTTATSAADTNSLLSAIWEGRAASPQMTN +HMKTMLSQQIW-PHRIRSGFPADVTIAGKTGTIGS-VRNEVAVVAFPDEPPIAVSVFTRA +ARSDLPLVDQAIGRVARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Marinisporobacter balticus TaxID=2018667 RepID=A0A4R2KC45_9CLOT +-kNLKDKIKNILNAIDGNKGLYMKDCSTNEIL-TINENRRFHAASTIKIAILYEALLQVQ +SKKRKLDDLYKLKSSDLIGGCGVLKLHVGLAVTLEDLITLMITVSDNVATNILHDIL-GK +DNINDSIQTLNIGNTFFARKLMIPDSN----LYSYTTAKDLGILLNEFLGCKKLNEDIAN +KGLEILYKQQY-NDRISD------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Halococcus agarilyticus TaxID=1232219 RepID=UPI0009AC2516 +---FDELIDEYRDRIEGRLGIFLGRPKPNDIVyTVRPDERFTSASMIKVPVLWTLYDCYD +GCLDDLTTPNGIAEANRVDGSGVFHLLADLNPSLEDLARAMIAISDNTATNELIDHL-GC +ETVTERMHELGLTETRLGRKMMVTDELPPDALENLISPRDVAMLFADIHRGETLSRRAYE +RLRVPLRHQKD-TSMFARYRPLDHRMEHKTGWLST-AALDAGVCHAGND-PLVYAVFLDG +MDH-GGDGTDVIAEIGDAVH--- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00036752AE +-----------LDRIPGTVSAYLARLDARPTW-TRHPDTTHYAASTMKVAVLVALYRALE +AERLAPDTAVPVRNEFDSAQPGAAWDRLGGTASLRWLAERMIVRSSNLATNLLLDQV-GL +PAVADVWARAGARRSSTGRGIEDFAAR-TAGITNLVTAADLAALLRDLALGALATPESCA +AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCHTG +DHPDRSADTQLLADVSAHA---- +>[subseq from] serine hydrolase n=1 Tax=Oceanobacillus polygoni TaxID=1235259 RepID=UPI0011F1E530 +--------------------------SSEGSI-GINANTPRKAASIVKLFILAEVLQQIE +AGSVQKEQLISIQPEEMVEGAGVINYLTNHDYSYQNLVELMIIVSDNTASNILLDTI-GI +ERLNYSIKKLGCQHTTINRKFMDHQAQ-ANGDENMTTATDVAYLLKLFSNENGYSSSIRR +EVRRILKNQQF-NHKLSAFQMDKLKIYHKTGELP-GVEHDAAIMESNGK-KLEVAVLTEG +WEN-NGIAHHFMGEVGRYLMN-- +>[subseq from] UPI0013E905DD UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0013E905DD +-------IKKYLETREGNYSFYFEEINSGYLY-GLNENKEMVSAGCIKLPLAMSLLKEVQ +NGKIDLQSKIKIKSGDKIHSNGIIHEFSGKEYSIFDLLIAMLIQSDNTAANKIIEVL-GM +QRIDELFKDMGLKNTKLKRITTDIKLE-QEELENTTSSFDLSKCFKLLYLKQYLNEENSD +LLIRILKKQQV-TNKLPFYAPKQIQIANKGGSLET-VENDTTLMMIEKGN-FLFTVMANN +LP-NNVYGITTISRVGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=UPI00097859E5 +------------------------------------------------------------ +------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM +TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS +KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ +VQNPAAERQA-IGA--------- +>[subseq from] Beta-lactamase n=1 Tax=Natronorubrum tibetense GA33 TaxID=1114856 RepID=L9VNY0_9EURY +--ELRSTAEQIDEGLDGRLGVVVCDVGNGEPLlSIRSRDRFGAASIVKLPILYALYRTYD +GRLEALDRPHQIAPENRVGGSGLFHLLADPTPTVEDLATAMISVSDNAATNELIDHL-GF +DDIAAAAADLGLEGTHLGRKMMQTPASNGHRYVNWVTPLDCVVLLSDIHRERTLSSAAYE +QLSRPLAHQHD-GSMVPRYLPPDAEIRHKTGNLPS-VAADTGLLTVDGR-TVAYAICCDG +LER-RGEGVDAIAKLGAGVY--- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. Ade.TY TaxID=1391647 RepID=UPI00041C3230 +-----KEIKKYLESRIGTYSFFFEDLESGFVY-GYNENVKITAAGCMKLPIAVSLIKDVE +RGKITFMDKIKIDGVDKVYGTGIIHEFNSRDYTVFELLVAMLIQSDNTAANKIIDIV-GM +DRINEDIKEMGLENTKLNRKTADERRD-NINVENLTSARDLSKIWKHLYKATYLNEENST +MLIDILRRQQI-KNKLALYIPDNYEISSKTGDKT-GVENDTALIQLSKGT-FTFTVLSTE +VPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Secreted beta-lactamase n=1 Tax=Streptomyces sp. W007 TaxID=1055352 RepID=H0B9D5_9ACTN +-----------------------------GEV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL +DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA +QVRELMARQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART +RQASRTAVDSAIGATARIAVDH- +>[subseq from] serine hydrolase n=1 Tax=Jiangella muralis TaxID=702383 RepID=UPI0009FB5B64 +------------------GFLHAVDVGPGAEV-GVEPDAPVVTASVFKIPVLVELCRQFA +TGERSAADRLRVPAGGRTLGPTGLSVMLDDALSLRDVAYLMMCVSDNHATDALMALL-GR +EKINAGTAALGLPATVLEEDCAGLFRVLDAETTNRSTPRETTTLLRRVWTTDGLPEAACD +EIRRILGLQVW-PHRLTSGFPDDVKVSGKTGTLSH-VRNEVGVVEYPDGGTYAVAVFLRL +PGAENPAADAVIGTAARIAVDH- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A2E1J157_9BACT +----HEEIKSLISSFNGEVGFYFSHLEKGIQF-GINENKIFPTASLIKIPIMVQIFNRIE +NDNLNIDSLLIYDSSLIDYDDSIARFKEKETISINKLLTHMITFSDNHASLWLQNIAGGG +AKINNLLKENNFNKTRINSRTINREDQYLKYGWGQTTSKEMSELLIKIRDGDLISKKSSN +NMYRHLTRIYW-DDEALSQIPNHIQVASKQGAINK-SRSEVVLVNAPNGD-YVFCIITNN +QFDEENEGFALIRKISKILWNNf +>[subseq from] Beta-lactamase regulatory protein BlaB n=2 Tax=Gordonia terrae TaxID=2055 RepID=A0A4U9Y2S3_9ACTN +------------------------------EY-CHDADTPVVLASVYKLAVLISLCRIAD +RGDIDLSASVTVDPTRWAQGPTGLALFVDPVLSWRDLATSMMTASDNVAADVILAQI-GL +QQVRDDLVELGLTNTRIVGGVAELHEAYDAAYSSSATPRDCTTLLDAVWTDRAASASSCE +FVRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AVRNEVGVVEFPGELPLAIAVFTMS +ARSELPEVDRAIGLVARAVVT-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Synechococcus spongiarum SP3 TaxID=1604020 RepID=A0A0G2HMX8_9SYNE +---LEERFQALAASQDLLAGAYVAVLGDGQHA-RLNSDRATAAASAIKTPLLLLTLLARS +QGELRWDETLQLQPHLVGGGSGWMGSEPPGSFPLYMAAREMITVSDNTATNLLMERLGGM +EAVNRRFLALRLRGTRVNNWLPDLGGT------NTTTPRDLALTLAMAENSALLSQQDRD +RFRAIHGSSRP-NSLLPLGFLQGVRILNKTGDIGT-AYADAGTIELPDGRRAVAAFLVEG +TEYNSPRMRRLIQNMAAAT---- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 844.5 TaxID=2485140 RepID=A0A3N1L6Q3_9ACTN +--TAQKNIRAAFEEAGVEGFLFARDIDGSRTI-GVAPDELVCLASVFKIPVALGYAREAA +AGRLERTERHSVEQRYRDGGIGTSGCADPVEMSLRDLVHMMLTMSDNAATDVVLERV-GL +DTVNALLAELGRNRTHLIGGCLELTGC-VPERTTRSTARDTAELLAQIWRDEAGPAEACA +EVRTVMSHQIW-PHRLSSAFDDSYRVSAKTGTLP-GWRNEAGVVEDTDGGRFAVAVFTRA +RIADNPAADRVIGTAARLAVDE- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces qinglanensis TaxID=943816 RepID=A0A1E7K3P7_9ACTN +--------------AGVRGWLHVAELHRAARV-TVDADGLALMGSVYKLPLMVAYCRQVD +AGALDPRQRLTLPAGDRLPGPTGLSLLRDEVMSLRDLVVMMMSISDNAAADAVLRQV-GT +AAVEETCAALGLHRTRLDGGAAGSLAVYDPAWAAATTPAELAVLLRAVWLDEAASPGSCA +FMRATLGLQPW-QHRLAAGFPDEVAVYGKTGTFG-AMRHEAGVVELADGRGYTAVVFTQA +ARADLPRADAVIGAAARTAVEH- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0006DA215E +-----------------------------GEV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL +DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA +RVRELMARQAF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART +REASRTAVDAAIGATARIAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. MYb43 TaxID=1848688 RepID=A0A2S8UTT7_9MICO +---IGQDIAEIFADAGATGFLHARQIGDGPEV-NAGANEPVVLASVFKILVLTAFVRAVA +AGDLDPTERTTVTARYRIGGVGTAGFADDVEASWRDLALNMMTMSDNAATDVIYHRL-GA +DAVNRVVSDLGLQKTRLIGCCEDLFAVVHPLKTSHSTPRDVATLLNALWTDTAAPAEACR +QARDTMALQIW-PHRLTSGFPGEVSLAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA +GSL-ADRQPLVDASIGRAAF--- +>[subseq from] DNA-binding transcriptional LysR family regulator n=1 Tax=Ponticoccus gilvus TaxID=519423 RepID=A0A4R6LW60_9ACTN +----VAQIRDVWRAVGVVGGLHARDLRSGAML-AVDADDAWPMASVAKVPLGIALHRAAD +AGLLGLDQALTLRPDGRTSGTTGISAMADPVLSLRDALYLALTISDNAAADAIWDTL-GA +DRVQHLLRQLPPDQVRLGEATRDLYDSLDGPYACRATAAGATRMLELIWSDQAASPAACA +AIRDLMRRQVW-AHRLASGFPADLEVAGKTGTAGD-HRHEIGVVSYPDGRRFAVAVFTRL +QQETPHHRDWAIGETARLAVN-- +>[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00048BB48B +------------DRTPGTVSASLGHLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE +AGRLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL +PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGTLALGALAAPESCA +AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA +DPTDASPDDDACQLIADISARA- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. GLM-1 TaxID=2267691 RepID=A0A427TLY2_9PSEU +----------------VRGFLHVRRLGSPAST-GIGADSPVVLASVVKVPLAYEFARQVA +AGLLDPADRVRATAADRLGGTGSAGFEDDVSYSLRDAARLALSVSDNTAADLLFDRV-GV +ANVRSLLAELGLTRTSVIGAPRDLLRALDPLRTSATTPREMTALLAAIWADPA-----GE +PVREWMSAQVS-WHRLTAGFPPEVAVAGKTGTMP-GIRNEIGVATYPDGVSYAIAVFTVG +GSETRPDIDRAIGDAARAAVEQ- +>[subseq from] serine hydrolase n=1 Tax=Oceanobacillus damuensis TaxID=937928 RepID=UPI00082CC838 +---LESALLSLINDDRENFSIAVH-TDEG-NI-NINADKPRQSASLAKLFILAKVYEQVE +TGSLLLDKLVYIDSKKMVGGSGVISYLTNCHYSYQNLVELMTIVSDNTASNILLETI-GA +EQTNQFARKLGCSNTNLGRNFMDQVSR-MDGFENVTTACDVCNLLTHFSRENFFTENSRR +NIKKILGNQQF-NSKLSSYHQSTIKIYHKTGELQ-GVEHDAAIMEANGN-TMEVAVLTEG +WSN-NGMAQYYLAEIGRMLR--- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000487F14A +------------DRMPSTVSTYLARLDATPTW-TRHPDTTHYAASTMKVAVLVALYRALE +AGRLTPDTAVPVRNEFDSAQPGAAWDRLGGTAPLGWLAERMIVRSSNLATNLLLEQV-GL +PAVADVWARAGARHSSTGRGIEDFAA-HAAGITNPVTAADLAALLRDLALGALATPESCT +AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCSTG +DHPDDEETCQLIADISARAF--- +>[subseq from] serine hydrolase n=1 Tax=Nocardioides sp. KC13 TaxID=2711220 RepID=UPI0013EB882F +----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD +RGLLSLDEPIAVHPDSAVTGSRFEWEAVGSALPLGDLVRRSLTVSGNLAVNLVLERV-GL +EEVAAVLADAGVTMTTVSRGIEDAPA-REAGLQNLVTANDMGKLLTKLASGRLLSPESTA +ELEGILVAQEY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIRPAQGEPQVMVVLTTG +LDD--DESEFRISEVARYLWS-- +>[subseq from] Beta-lactamase n=1 Tax=Caulobacter segnis (strain ATCC 21756 / DSM 7131 / JCM 7823 / NBRC 15250 / LMG 17158 / TK0059) TaxID=509190 RepID=D5VFF5_CAUST +----------IAARAPAVLGVAAEDLGTRQIW-GFNGDRAFVLGGAARVPVLAAVMAERA +AGRLDLNEQIDARDVDLSPPSAVADAWPGREYTVAEL-EALARTGDNTALDLLTKRIGGP +GAVNGWLDVRQLRGVSVDRYRRQVETQRAADPRDTTTPVGVVRLLETFNTREAFASADPR +LLLG----ND--PGYLASALPEGAKIWQAAGSARVAESHAVALIELKDGRRIALAVFLTR +STTDVAAREAIITEAGRTVLKSf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CB01635 TaxID=2020326 RepID=A0A2M9JH14_9ACTN +--ELVETITGRAAEVGVQVRLHAADLDSPRQV-GIDADEPVVTASVFKVPVAVELARQAA +DGELDLAERITVPPGHPTAPYGLATFLHDVTMSWYDLAVLMIGISDNVATDLILGKV-GK +AAVAETLRRLGLPQTAVPHDCGDLLRALTPEETCRTTAAESTRLLGLIWRDEAAPAAACA +DVRRWLELQVW-PHRLRSGFADDVTISGKTGTLPS-LRNEIGVVEYPDGGRYAVGVFTRA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] serine hydrolase n=1 Tax=Clostridium saccharoperbutylacetonicum TaxID=36745 RepID=UPI0009838EBA +------EVKRYLESRIGTYAFFFEDLESGFSY-GYNENVQMTAAGCMKLPISVSVLKYVE +DGKIDFLDKIKIEEADKVYGTGILHEFDNREYTVFELLVAMLIQSDNTAANKLIDIV-GI +DRINDDIEAQGLKSTKLNRRTSDERAA-SNGIENITSALDLAKIWKHLFNSSFLNEKNSI +MLMDILRRQQM-KNKLALYIPDDYEISSKTGDKAN-VENDTALIHTHKG-SFTFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridium beijerinckii TaxID=1520 RepID=A0A1S8P8Z1_CLOBE +------EIKRYLESRIGTYSFFFEDLESGFSY-GYNENVQMTSAGCMKLPIAVSIIKHVQ +EGNSTFLDKIKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIDIV-GI +DKINDDIEAQGLKNTKLNRKTSD-ERAVSNGIENITSALDLSKIWKHLYDSSFLDEKNSK +MLMDILQRQQM-KNKLALYIPDDYEISSKTGDKAS-VENDTALIHSPKG-SFTFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Serine hydrolase n=2 Tax=Bacteroidetes TaxID=976 RepID=A0A257ITV9_9BACT +--KLQKIIEEATYGFNGVIGVYVENLKTGKFA-EVNADTIFPTASMIKIPIMIGTFSHIL +NGKLRYDQILTYKDSLKYDEGLVGSFRDSTKIPVSELIYLMESVSDNTASLWLQGLV-KG +QRINQLMDSLGMQNTRVNSRTPGRSAFQKTYGWGQTTPKEMASLMKMLRKGEIFTQDASY +RMYKTLGNQYWDG-EGLSQIPENTKTAYKSGAVDR-SKSEVMLVHAPHGD-YVFCMITKN +QTDKNNEGYRAARRISSSLWKYf +>[subseq from] Uncharacterized protein n=1 Tax=Clostridium sp. 7_2_43FAA TaxID=457396 RepID=V9H2D7_9CLOT +-----KEIKKYLESRIGTYGFFFEDLKSGYIY-GYNENVQMVAAGCMKLPIAVSLIKSVE +DKKIDFLDKIKIDGKDKVYGTGIIHEFNEREYTVFELLVAMLIQSDNTAANKIIDIV-GM +EKINKDIKEMGLKNTVLNRKTTDER-KTKSEVENITCALDLARIWRHLYNSTYLNEENSQ +MLIDILTRQQI-KNKLALYIPDDYEISSKTGDKN-GVENDTELIRLSKGN-FTFTVLSMG +IPNS-VYGTVTLAKCGKTMWD-- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium UBA8153 TaxID=2060924 RepID=A0A3C0FBB5_9FIRM +------------ARTTGVIGFSILDLGEGKEY-SHLGDTVFPTASTIKIPILVALAHQVF +RGERAWDQRVPVPRA-RAGGSGMLQWLQHVELSVWDLASLMIAISDNVATNICIDMV-TM +EAVNRLLDDLGLSRVRLRRKMMDPEAV-ARGDENVATPTQLTRLMSKLHYQVEIPEPVCH +DVLAILRLPKQG--PFTEALPVEVPRANKPGGLP-GASIDSGIVYLPRR-PYALTVMGTF +LEED------------------- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535XMR4_9CHLR +--ELVQQLDGLISSFPGGAGIWIADPTVATPLfAHDPDEQVIAASLYKLGVLAEAERRVD +TGDLHYNDAITIQPEDITLDGSF--EDAGTQLTLDEALEAMITISDNGSALALWRIL-GG +SNIDATLEKAGIKNFHVA---------FDDTEDNWATPHAIGTFFTLLAKRQLISGAASD +RMLARLERQQI-NDRLPAQLPPGVVVAHKTGNLTS-VTHDAGIIFTKTGPRVVVAMTWDA +PD---EDAANFISSIGSLVYS-- +>[subseq from] Beta-lactamase class A n=2 Tax=Hungateiclostridium clariflavum TaxID=288965 RepID=G8LTV1_HUNCD +-kDLLSSINDVIKNETDIVRVSVYDFATGTTV-SYNGQERFYPASLSKIVNLLCFFEEVQ +KGNFSLSSVYTLKQSDKYIGTGNLQYQANGTYTYEDILSRMISLSDNVASNIIFDAL-GR +ERLDAFCEMYGLKDTRIYKKFYDGDKNFP---SNYSTADDLTRMLVLLENRLSVEDNLSI +LGIEYMKETVN-KDRIALYAPEDVVIANKVGFISR-LSGDMALVYFPDREPIALTIVVED +DNINQEKANELIGTLSREIIDYf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CB01201 TaxID=2020324 RepID=A0A2M9JB92_9ACTN +-------ITAALTDAGLGGALCATDIDTGATV-ALAADTPVSTASVHKLCLVATLYREAA +AGRLDPTTPVDIPAGARAPPTGLAVMRDAARLSLRDLASLAVAVSDNAAADVLWDHL-GL +DTVNATMNALGLTRTVAVHNQAGLYAVLDPARTNRSTPREIAALLTAIWRDEVCAGAWGE +ELRAVLGVQAW-SHRLASGFPDDVRVSGKTGTLPT-QRHEAGVVEYPDGGRYAVAVFTRA +ASATLPAADAAIGRAARVAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Shapirobacteria bacterium CG08_land_8_20_14_0_20_39_18 TaxID=1974883 RepID=A0A2M6XDE6_9BACT +--EIIKQVNNLTANLTGDYGLYVFNLTTKISF-GISENQVFKAASLMKLPLILTLYKNVE +AGKIDLQTKYTLKAADKRPGAGSMYYKPAGTYTYQKMVELMGQQSDNTAFNVFRNLL-GD +EQIQKTIDDLGMTKTNFTDFE--------------TAPAEIGLFFRKFYSGSILTRAHRD +EILGYITKIFD-ESRIPAGIPAGVRVTHKVGTDT-GVASDGGIVFG--TKPYIIVIMSDK +NLK--VEADAVLPKISSAVWE-- +>[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. MYb72 TaxID=1848693 RepID=A0A2S9AFS1_9MICO +--AVEADIARIFADAGARGFLHAREIGGGPEV-GVGSDDPVALASVFKILVLTAFVRDVA +AGALDQTARTTVTARYRIGGVGTAGFADDVEASWRDLALLMMTMSDNAATDVIYHRL-GG +DAVDRVISDLGLDRTALIGCCEDLFAALDPPRTSHSTPRDVTRLLTALWTDAAAPASACE +QARTIMAQQIW-PHRLSSGFPNGVQIAAKTGTLPR-WRNEAGVVTYPDGRQFAVAVFTLA +DTL-ADRQPLVDASIGRAAL--- +>[subseq from] Beta-lactamase class A n=1 Tax=Haladaptatus litoreus TaxID=553468 RepID=A0A1N7B1H7_9EURY +--ELGEYIERYADRIDGELGVFLYGPDEFDTVcARNARRAFRSASVVKIPILYALYERYD +GRLDSLAESCPLSPENRVGGSGILH-LLDATPTIEDLARAMIATSDNAATNQLIDLL-SM +TTVNDSAAKLGMKHTRLARKMMTTLEVPENEPANVTSPVDCARFFADIACEATLSANAYE +RMRVPLSAQKD-TSMVPRYLPYETEIMHKTGWLPT-AALDAGLLSVPEKPPLVFSVFVDS +VSN-GADAADAIAEIGDAVF--- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. 05-2254-4 TaxID=2022492 RepID=A0A260MNB7_9NOCA +--TTDEQLRAVFADAGCRGWVRAERVDGTGTVvDFEGDDPVVAASVWKIVLLVATARAFD +EGVLAATGSVRLVPAQCSPPTGIASYADPVTMSWRDVARSMITVSDNAAADALLGAL-GL +DALSQVIDSLGLEDTRIVGGTKTLGDGFDPAYTSCTTPRDSNAVLRAIWLGTAASPEQCR +YMKGVLSQQVW-PHRIRSGIPPDVEVAGKTGTIGP-IRNEVAVVSFPGEVPVAVSVFTRA +ARMDLPLVDQAIGHAARVAV--- +>[subseq from] hypothetical protein n=1 Tax=Caldanaerobius polysaccharolyticus TaxID=44256 RepID=UPI0006896E56 +-qPLKQKIAEYISSNNLSAGVYFKDLTTNTDF-GINENKAFTAASTVKVPIVLYLYTLAS +EKKVDLNAKIAYDKDDFESGAGVLEYKPGDKYSLRTLANQAITTSDNIANRMIMRYL-GK +DNIIKFMKNLGGKTV------------YPG-GKNMTTAKDMVTYMEAVISFTKANSELGK +MLLDDLAHTVY-NSGIPALLPDGLYIPHKEGDLHD-VANDVGIVYCQ--RPYILAVLTDK +NK-DVETGFKHIARISKMIYDY- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CB00013 TaxID=1703945 RepID=UPI00093F8EE6 +--QVTETITERAKEVGVRVRLHAAEIDGTRRI-GVDEHTPVVTASVFKVPIALELAKQGA +EGALDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILDRV-GK +EATEKTLRDLGFEHTTVSQDCGEVLGALQPEHSCATTAEEITRLLGLIWRDEAAAPAACA +DVRRWMDLQVW-PHRLRSGFPDGIRVGGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. 1-11 TaxID=2590549 RepID=A0A510TUM8_9ACTN +----EETIVEVFAAGGCRGSLSVREIDGPRRL-SVAGGELAVAASTFKIAIGLEFFCRAA +EGDVDPAERVAVSPAEASPGQGLCITEDPVEISLRDTARLMLTISDNTATDVLIRRV-GI +ERVRARLAGLGLTGFHLPRYELDTAAGMRPGRISSVTADDLAALLRAVWRDEAGPAQACS +DLRRMMGQQRL-TRKIAAGFGPHVQVVSKSGTVPGGVSNDAGVVAFPDGRRYAIAVLTRP +LTPGAPTREDILGTAARVALDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Clostridium cavendishii DSM 21758 TaxID=1121302 RepID=A0A1M6RZQ3_9CLOT +------EIKKYLETRIGSYSFFFEDLKSGFIY-GYNENVPMVAAGCMKLPIAIALIKNEE +EGKINFLDKVKIEGKDKVYGTGIIHEFDEREYTIFELLVAMLIQSDNTAANKIIDIV-SI +ERINEIIKEMGLTNTVLNRKTTDER-NVKPEVENLTSASDLARIWRHLYKTTYLNEKNST +MLIDILSRQQI-KNKLALYIPDDYDISSKTGDKQ-GVENDTALIHLHKGN-FTFSVMSTG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Beta-lactamase n=1 Tax=Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040) TaxID=521096 RepID=D5UMR9_TSUPD +--ATAAAIAEVFADAGCNGWLHARVVGADAEL-SVSGHEPVVPASVYKIVLLVAACRAFD +SGRLDPRQRVTVDPRTATPPTGIATFDDPVQLSVRDLARSMIAVSDNAAAGTLLSLV-GL +DEVQRTARELGLRRTVIAGGDAEMHTAYDPSFGSATTAADATALLAAIWSDTAASPQGCA +FARSALAGQVF-RHRIASGFGPGAEIAGKTGTLG-ALRNEAAVVSYPGEHPVAVAVFTHA +ARND-PALPRVDAAIGRVAL--- +>[subseq from] PEGA domain-containing protein n=1 Tax=Candidatus Dormibacteraeota bacterium TaxID=2052315 RepID=A0A2W5YD62_9BACT +-----TELQAYLTATGGTFGVYLEQLSSGRTL-AIDQDASMEAASVIKIPVALYLLSQVD +AGQVKLSDKVKLEAKDFMGGTGILYGSAKAGIPYQDLLADLVRQSDNTAWQALQRVL-DP +AKIDGFAAAQGAPD---------CHQ-----LSDQCTARQAGQLLSKLGRGGLLSGDSTD +RLIQLLETTVF-NDRINYYLS-GVSIAHKIGIDGN-VINDCGIVYAATGA-FTICVFTRT +AD--QPTGIQAIRDIARAAYRY- +>[subseq from] Beta-lactamase TEM n=1 Tax=Clostridium ventriculi TaxID=1267 RepID=A0A173YT49_CLOVE +-----KEVEKYLKSRTGKYGFFFEDLYSGYSY-GYNENVKLISAGCMKLPIAVALMKCEE +EGNIDYLQKIRVNSSDKVYGTGIIHEFGEKEYTVFELLVAMLIQSDNTAANKIIDMV-SM +DKINETIKELGMINTKLNRKTADERN-YISGIENYTSAKDLCILWKNLYNKTYLNENNSQ +MLIDILARQQI-KNKLALYITDDYEISSKTGDKK-GVENDTALIHTNKGD-FTFTVMSSD +IPNS-VYGTITLAKTGKMIWD-- +>[subseq from] serine hydrolase n=1 Tax=Kocuria salsicia TaxID=664639 RepID=UPI0011A0ED85 +-------VTGILRDATGAVAVRVIDAPELPAF-GWRADEAFPAASLYKLVVMVAFCRAVD +RGDLDPTALVTLRPEDRADPTGLAICQDPVRISWRDLVRLMMTVSDNAAGQAVLREV-GH +ARVRDVLREMGLSSTVVRPGPAPDPVGYDPLLVSATTASDLVALLCAIWQDRAASTAQCA +FMREVMSQQAWGHRFAEAFSYPGAGVAAKTGSFG-ALCHEAGVISHPGEKSIAVAVLTRS +VRRQIAVSNRIVGQIARHCVRSy +>[subseq from] Beta-lactamase n=1 Tax=Clostridium sartagoforme AAU1 TaxID=1202534 RepID=R9BUA5_9CLOT +-----KEIKKYLESRIGTYGFFFEDLKSGYIY-GYNENVQMVAAGCMKLPIAVSLIKAVE +DKKIDFLDKIRIDGKDKVFGTGIIHEFNEREYTVFELLVAMLIQSDNTAANKIIDIV-GM +DKINKNIEEMGLKNTVLNRKTTDER-KVKNEVENITCALDLAKVWRHLYNSTYLSKENSQ +MLIDILTRQQI-KNKLALYIPDDYEISSKTGDKN-GVENDTELIRLSKGN-FTFTLLSMG +IPN-SVYGTVTLAKCGKMMWD-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces atratus TaxID=1893 RepID=A0A2Z5JQJ3_STRAR +-----NRIRTAFDDAEVQGYFFAREVDGDRTI-GVAADEPVCLASVFKIPIALAYAREAA +AGRLDRTERHSVDPHYRDGGIGTSGCADPVEMSLRDLVHMMLTMSDNAATDVVLARV-GL +DTVNGLLAELGLRKTHLIGGCLELTGVCVPERTTRGTARDIAELLVRIWRDEAGPAEACA +EVRAVMSQQIW-PHRLWSGFDDSYRVAGKTGTLP-GWRNEAGVIEDRDGGRWAVAVFTRS +DRPDNSRADRVIGQVAALAVDE- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TSRI0395 TaxID=1703923 RepID=A0A1Q5BZE4_9ACTN +-----------------------------GEV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL +DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA +RVRELMARQAF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART +REASRTAVDAAIGATARIAVDH- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Roizmanbacteria bacterium CG11_big_fil_rev_8_21_14_0_20_36_8 TaxID=1974856 RepID=A0A2M6IU44_9BACT +-------------NKKDKYAVAVKNLETGESL-YINEDKEFLTASLYKIWVMAVVFQKIE +EGSLSIDDNLKQDVTILNKKFNIATEDLQSGFTVREALNKMITVSDNYAALLLNEKI-GV +VSLSKFLLDFGFDQSQISQP-------------PVTTAHDMNLFFEKLYRGEFANEQYTN +DMIELLLAQEL-NDSIPKYITDKVKIAHKTGHLYT-VTHDAGIVYTANGD-YIITIMSEG +EN--EPDAKEMMAKISERVYEYf +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 42 TaxID=1827576 RepID=A0A495CJI2_9ACTN +----------------------IWPPGEAREV-AVGADEPVVIASIFKVLLVLEFARQAA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNAAADLLLDRV-GL +DTVRLLAKELGLDRTRIVGGPRDVLEVLDPLRTNASTPRETSELLRLIWRDEAGAPEACS +HVRDLMSRQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMETGVVRYPDGGCYAVSVFART +REATRPRVDAAIGAAAAMA---- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces mirabilis TaxID=68239 RepID=A0A1I2MKE4_9ACTN +--------------------------GEAREV-AVGADEPVVIASIFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNAAADLLLERV-GL +DTVRLLAKELGLDRTRIVGGPRGVLDVLDPLRTNASTPRETCELLRLIWRDEAGAPEACS +HVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMETGVVRYPDGGCYAVSVFVRT +REATRPTVDAAIGAAAGIAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Aureimonas sp. AU20 TaxID=1349819 RepID=A0A0S2EUT0_9RHIZ +----------LGDETCGRLSLFAKDLSTGRTI-EADADRVMGTASCIKLFILIELLRRVS +AGDLALGDRIAVDAAQQVGGSGILKALSAGLMTLRDAAVLMMALSDNTATNMLIDLL-GL +ERINRTATELGCAHTRLINRIDF--EAIDGDITSVGTTRDFALALERIASGALFDEAASA +VALDILSCQLH-VDLLPRYLSQDLWVANKTGFFP-GFRGDVAIFTLPDRR-IVAAAFLDD +IEAPENPGARRLGEVGAALLA-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. EC080619-01 TaxID=1096856 RepID=A0A0P0SBF5_9PSEU +------------------------------EV-AVGADVPVVMASVYKLLVLVGYCRAVD +EGRLDPREPVVVPPGRTPGATGISALADPVTMSRRDLVTSMITVSDNVAADVVHAAV-GR +DRVAALPAELGLTGTRIRGGTADVLAALSPVFGSSTTAADATALLARLWRGELASDAGTA +FARQVLSAQIW-PHRLRAGFPASAAVAGKTGTVG-AVRNEVGVVTYPGEHPVAVAVFTHA +ARSDVPRADAAIGAAARTAVN-- +>[subseq from] Beta-lactamase CARB-6 n=2 Tax=Clostridium thermobutyricum TaxID=29372 RepID=A0A1V4SYK4_9CLOT +------EIKKYLESRIGMYSFYFEDLSSGFTY-GYNENVQMVSAGCMKLPIAVSLIKDVE +DGNVTFLDKVNIDVDDKVYGTGIIHEFNSRDYTIFELLVAMLIQSDNTAANKIIDIV-GI +DKINKDIKEMGLKNTVLNRKTADERS--KVEIENFTSSKDLGIIWKHLYNGTFLNEKNST +MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKK-GVENDTALIQLSKGN-FVFTVLSQD +IPN-SVYGTVTLAKCGKMAWD-- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=J8HYF7_BACMY +------------------------------------------------------------ +-------------------------------MTLGEIAEAAIRYSDNTAGNTLFKKLDGP +KGFEKELGQNGNKVTLADCFEPDMKEAIQGDICDTSTVKTFAINLKAFTVRDALQTDKRK +IPTDWMRGNATGDELIHAGVPKDWEVDDKSGAGSYGTPNDIAIV---------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Nocardia pseudovaccinii TaxID=189540 RepID=UPI0009FC5924 +--------EEIFRKAGVRGWVHARCFDCAGAV-GLGADEPVVLASVVKVPLVLEFARQVV +AGQLDPTDRVRASAADRLGGVGTAGCLDDVEFSLRDAAFFALTVSDNTAADLLFDRV-GL +DNVRSLVRELGLTETRIVGSPRYVVQAMDPLRTTASTPRDMTRLLTLLGQDLAGDPAACR +WVRQLMGQQLN-WHRLAAAFPSEVSVWGKTGSLP-AIRNEIGVVAYPGGSRYAVAVFTRA +DTQRLPEVDHAIGAAARLAIH-- +>[subseq from] serine hydrolase n=1 Tax=Gordonia sp. IITR100 TaxID=1314686 RepID=UPI000991442F +------------------------------EY-CHDADTPVVLASVYKLAVLVSLCRMAD +RGDIDLTASITIDPTRWAQGPTGLALFSDPVVSWRDLATSMMTVSDNVAADVILAHI-GL +PQIHDDLVDLGLTHTRIVGGVAESHAAYDAAYSSAATPRDCTTLLDAIWTDRAASAASCE +FIRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AVRNEIGVIEFPGEVPIAVAVFTMS +ARSELPEVDRAIGEVARVIVT-- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. KNN50.9b TaxID=2018303 RepID=A0A229TJA9_9PSEU +------------------------------ES-GLGPDEPVVLASVVKVPLVLELARQVA +AGQLDPADRLRVTAADRLGGTGTAGCADDVELSLRDAAFFALSVSDNTAADLLFDRV-GL +DNVRSLLRELGLARTRVIGSPRDVVAALDPLRTSATTPRDMTTLLAAIAGDTAGPPEACR +WVRQLMGQQVN-WHRLTAAFPPQVRVWGKTGSLL-AVRNEISVAEYPDGARYAVAVFTRA +PTSRLPDVDHAVGAAARAAIE-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces spectabilis TaxID=68270 RepID=A0A5P2XJY1_STRST +----EERVREVFARAGAEGALHAMDAPGGDDV-SVAADTPVAISSVFKVLLVLEFARQAA +AGQLDPRERVLVTDAHRLGGWGTAGCVDDVEISLRDLAYFALTVSDNSAADILLSRV-GL +DTVGMLARELGLTRTRIVGGPREALAVLDPRRANAGTPREVTRLLDLIWRDAAGPPEACA +RVRELMGRQVF-RHRLTSGFPDDVRIAAKTGTLP-GLHIEAGVVRWPEGDTYAVAVFARS +RAADLTRVDAAIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis thermalba TaxID=944492 RepID=UPI000E265553 +------------------------------ES-GLGPDEPVVLASVVKVPLVLELARQVA +AGQLDPADRLRVTAADRLGGTGTAGCADDVELSLRDAAFFALSVSDNTAADLLFDRV-GL +DNVRSLLRELGLARTRVIGSPRDVVAALDPLRTSATTPRDMTTLLAAIAGDTAGPPEACR +WVRQLMGQQVN-WHRLTAAFPPQVRVWGKTGSLL-AVRNEISVAEYPDGARYAVAVFTRA +PTSRLPDVDHAVGAAARAAIE-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. Ae707_Ps1 TaxID=1885572 RepID=A0A1Q8KIE1_9PSEU +------------------------------EV-AVGADVPVVMASVYKLLVLVGYCRAVD +EGRLDPREPVVVPPGRTPGATGISALADPVTMSRRDLVTSMITVSDNAAADVVHAAV-GR +DRVAALPAELGLTGTRIRGGTADVLAALSPVFGSSTTAADATALLARLWRGELASDAGTA +FARQVLSAQIW-PHRLRAGFPATAAVAGKTGTVG-AVRNEVGVVTYPGEHPVAVAVFTHA +ARSDVPRADAAIGAAARTAVN-- +>[subseq from] Uncharacterized protein n=1 Tax=bacterium TaxID=1869227 RepID=A0A3A0FMU4_9BACT +---------DELGADVGRFGVVARRLDDGLGA-GVNPDRVFYAASTFKLALLYEAELRRS +QGLLDFNAPLPLDESDLSEDLGTFENLPEDGLTIGAALEAMITLSDNASAVALLRLL-GP +EAIDATLATLGLKHTSVNTREL--P----------TTASDMALLMEAIVRGEGVDPEARG +HMRSLLLAQHS-RDGIPAGLPGSARVGNKTGTWEQ-ATHDVAFVETTSGT-YVVAVLSDS +DR-----DWGRIARVSGA----- +>[subseq from] Serine hydrolase n=1 Tax=Acidipila dinghuensis TaxID=1560006 RepID=A0A4V1NVE2_9BACT +---LEAALHAAIASHNGHVAVFAEDLATGRTV-AIDADTPVQTASVIKLAILYTALEEIR +DGKAHFEDKLTLKHSDQVAGSGVLTFFDTPVLTLKDALTMMIIMSDNTATNLAIDHL-GL +KNIDDQILALGLKNTWLYKKVFLPADDQKQFGLGKTTAREMASLFERFVTNTAATADDHA +LCNAHMLSNQFYRDSIPRYLEAQSEIANKTGALD-AVRNDVGVVFTKAG-PVVISMFTWG +NKDTDNQAEVLMAKLAKQIVGTw +>[subseq from] Serine hydrolase n=1 Tax=Caulobacter segnis TaxID=88688 RepID=A0A2W5V4X7_9CAUL +--ALQKAMEPIAARAPAVLGVAAEDLGTRQLW-GFNGDRSFVLGAAARVPILAAVAAEHA +AGHLDLGETIAVRDVDLSPPSRIADDWPARQYTVRELQDLA-RAGDNTALDLLTKRIGGP +GAVNGWLDVRQLAGISVDRYRRQIKTRHEADPRDTATPVGMVRLLETFNTREVFASADPR +PLLG---GD---PGYLAAVLPEGASIWQAAGSARVAESHAVALIALKDGRRIALAVFLTR +SPAEARAREAIIAEAGRTVMKSf +>[subseq from] serine hydrolase n=1 Tax=Nocardia anaemiae TaxID=263910 RepID=UPI0007A395E8 +---------EIFGKAGVRGWVHARCFDCTGEV-GLGSDEPVVLASVVKVPLVLEFARQVV +AGQLDPTDRVRATAADRLGGVGTAGCLDDVEFSLRDAAFFALTVSDNTAADLLFDRV-GL +DNVRSLVRELGLTETRIVGSPRHVLQAMDPLRTSASTPRDMTRLLTLLGQDRAGDPAACR +WVRELMGQQLN-WHRLAAAFPPEVSVWGKTGSLP-AIRNEIGLVAYPGGSRYAVAVFTRA +DTQRLPEVDHAIGAAARSAI--- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. MJM2582 TaxID=1427749 RepID=UPI000502EEAD +--QVTERINERAKEVGVRVRLHAAEIDGSRRI-GVDEHAPVVTASVFKVPIALELAKQGA +EGALDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILERV-GK +EATEKTLRDLGFEHTTVSQDCGEVLRALQPEHSCATTAEEITRLLGLIWRDEAAAPAACA +DVRRWMDLQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. 16K404 TaxID=2530385 RepID=A0A4R4UHP4_9PSEU +-------------ELPGRAGIASWDLRENAPV-LRGAEVEVHSASTIKVLVMITALRAVA +DGRLDLDAQVELPAE-RTRGTGVLFEVPSVPASLRDLINLMIVVSDNAATNAVIDQV-GF +TAIAECTADLGCTSTRIERHIMDTGA--PGV--LQTTALDQARVLAALAEGVALPPQLTR +HALTVLSRQQV-VDRIPLLLPENARCWNKTGEIK-GLRHDVALLSTDDTPQVVLAVLVDQ +LTD-------------------- +>[subseq from] serine hydrolase n=1 Tax=Clostridium ventriculi TaxID=1267 RepID=UPI0006DCAE1B +-----KEVEKYLKSRTGKYGFFFEDLYSGYSY-GYNENVKLISAGCMKLPIAVALMKCEE +EGNIDYLQKIRVNSSDKVYGTGIIHEFGEKEYTVFELLVAMLIQSDNTAANKIIDMV-SM +DKINETIKELGMINTKLNRKTADERN-YISGIENYTSAKDLCILWKNLYNKTYLNENNSQ +MLIDILARQQI-KNKLALYITDDYEISSKTGDKK-GVENDTALIHTNKGD-FTFTVMSSD +IPNS-VYGTITLAKTGKMIWD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. b84 TaxID=1827631 RepID=UPI000BEF37CD +-----------------------------GEV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL +DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA +QVRELMGRQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART +RQASRTAVDSAIGATARIAVDH- +>[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000BEFC845 +-----------------------------GEV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL +DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA +QVRELMGRQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART +RQASRTAVDSAIGATARIAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A432F057_9GAMM +--TLENELNQLCDEQPFHTGWYVKNLRTGAVL-ERHGNAVVPSASTRKIAIMMAALKAVN +EGELSLSQPVTMASRFKNNDSGCFQHLQSDFIQLQDALVMMIIVSDNTCTGAVADLV-GL +ELINVLCQSIGMVDTVHRYGIPGMAGYLPADKTNSTTPADVALLLEIILQGVVCTPDLCQ +LAIDILSWQRL-RNRIPARLPLGTKVAHKTGTTAK-NYNDAGIVYAGDRPLFLISAYTDN +VPAEHTVAYDLTARLSRLCWDE- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. TaxID=1506 RepID=A0A348Z7C3_CLOSP +-----KEIKRYLETREGEYSFYFADLKSDYTY-GFNEDLKMVAAGCIKLPIAMAVMKEVE +STNIFLDQLVTITNDDKVSGSGIIHELEGRQYSIKELIVAMLIQSDNTAACKLINTI-GK +DRINSIIHDMGLTSTFIKKYPSGEKED--FDNENITTSYDLCKGLALLSKGKVLNGEHSK +FILEVIRRNQL-TTGISFYWPKDVKTAHKAGSLE-GIENDIVLLNLEKGD-FVFVVMSRN +LPS-NVYGVS------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Caldanaerobius fijiensis DSM 17918 TaxID=1121256 RepID=A0A1M5F2E1_9THEO +--PLKQKIAEYISANKLSAGIYFKDITTNTTF-GINEDKMFVAASTIKVPIMLYLYTLAA +EKKVDLNTKIAYDREDFESGAGILEYIAKQGYSLRTLANQAITTSDNIANRMIMRYL-GK +ENIIKFMKDLGGQTV------------YPG-GKNITTAKDLVTYMEAVIAFSKANPELGE +TFLNDMAHTVY-NAGIPALLPDKLFIPHKEGDLDD-VANDFGIVYCQ--RPYILAILTNK +NK-NADTGFKHIANISKIIYDY- +>[subseq from] serine hydrolase n=1 Tax=Clostridium ventriculi TaxID=1267 RepID=UPI000DD44103 +-----KEVEKYLKSRTGKYGFFFEDLYSGYSY-GYNENVKLISAGCMKLPIAVALMKCEE +EGNIDYLQKIKVNSSDKVYGTGIIHEFGEKEYTVFELLVAMLIQSDNTAANKIIDMV-SM +DKINETIKELGMINTKLNRKTADERN-YISGIENYTSAKDLCILWKNLYNKTYLNENNSQ +MLIDILARQQI-KNKLALYITDDYEISSKTGDKK-GVENDTALIHTNKGD-FTFTVMSSD +IPNS-VYGTITLAKTGKMIWD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces thermoviolaceus TaxID=1952 RepID=UPI00143AB71D +----AEAIAADWAALGMRGSFLARRLDTGEQL-GFDIDDPVPLASVVKVPFALVVLDRIA +AGLLDAAQPVTVDPATSSVGSTGLAARHPATVAVGDLLALMLAVSDNAAADALFDLV-PP +EETDARLREWGCTDIRVRHRMQRMYETLDPAHANAGTARGLVDLLQRVWQDEIARPAATA +ELRRLMAAQVF-THRLAGDLRDTIRVSGKTGTFLH-LRHDIGVVEADSGHRVAMAALTRS +DRALAPDIDAAIAAAARQAF--- +>[subseq from] Serine hydrolase n=1 Tax=Nocardia sp. CICC 11023 TaxID=2545717 RepID=A0A5N0EF48_9NOCA +---------EIFRDAGVRGWVHARCFDCGAEA-GSGADEPVVLASVVKVPLVLEFARQVA +AGQVDPADRVRAGGADRLGGVGTAGCHDDVELSLRDAAFFALTVSDNTAADLLFDRV-GI +DNVRSLVRELGLDATRIVGAPRHIVQALDPLRTTASTPREMTRLLTLIGQDLAGPAEACG +WVRDLMRRQVN-WHRLAGAFPPEVQVWAKTGTLP-GVRNEIGVLEYPDGSRYAVAVFTRV +ESQRLPEVDRAIGAVAAHA---- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ297 TaxID=2572905 RepID=A0A559V971_9ACTN +---VAERIGEIFGRAGVRGCLHVVDVDAGGEV-ALRADEQIVIASVFKIMVVLEFARQAA +AGQLDPTERVLVGAADRLGGWGVAGCADDVEVSLRDLAYLAMSVSDNTAADLLLRRI-GA +DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEHTSSSTARELTRLLRLVWRDEAGPAPACA +MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRT +ERARRIDVDLAMGEAARTAVD-- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A6B1N2I1_9ACTN +-----AALESVIAEAGVTGFVHARDIDHGHEI-GVRADEPVIVASLRKIPVALAYARRAA +AGQLDRAARHTITADNREGGGIGTDSCLHDVMSTRDLAFFMMSMSDNAATDKLMEIL-GV +DYVRRVAAKSGCPRIPVGRYRDLWDPMLDARRSVSSTPREITTLLTAIWRDEAGPAEACA +EVRDLMGHQLS-THRLIAGFDDDVRVAAKNGSLW-GVLNEAGVVEYPDGGRYAVAVFLRT +PQGRNPAADAAIARAARTAVD-- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium sp. C8 TaxID=1667357 RepID=A0A0G9LDC4_9CLOT +-----KEIKKYLESRIGTYGFFFEDLKSGYIY-GYNENVQMVAAGCMKLPIAVSLIKAVE +DKKIDFLDKIRIDGKDKVFGTGIIHEFNEREYTVFELLVAMLIQSDNTAANKIIDIV-GM +DKINKNIEEMGLKNTVLNRKTTDER-KVKNEVENITCALDLAKVWRHLYNATYLSKENSQ +MLIDILTRQQI-KNKLALYIPDDYEISSKTGDKN-GVENDTELIRLSKGN-FTFTLLSMG +IPN-SVYGTVTLAKCGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=UPI000A17A1F0 +------------------------------------------------------------ +------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM +TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS +KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ +VQNPAAERQA-IGA--------- +>[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. EPR-157 TaxID=1813677 RepID=A0A164PHQ4_9NOCA +--------------AGCRGWLRAQRIDDGPVV-DVNGHEPVVAASVYKLVVLVAAARAFD +SGHLDPHTQVRVVPADCTPPTGISTFTDPVTLSWLDLVRSMITVSDNAAADILLGAL-GF +GIVEQIIDEFELSDTRIVGGTAALQGAYDPAYTTATSAADINALLSAIWEGRAASPRMTD +NMKTIMSQQIW-PHRIRSALPADVTVAGKTGTIGP-IRNEVAVVVFPGEAPIAVSVFTRA +ARSDLPLVDQAIGRVARIAVT-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 94 TaxID=2035218 RepID=A0A2G7AH86_9ACTN +-------------------------PGEAREV-AVGADEPVVIASIFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNAAADLLLDRV-GL +DTVRLLAKELGLDRTRIVGGPRDVLDVLDPLRTNASTPRETSELLRLIWRDEAGAPEACS +HVRDLMSRQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMETGVVRYPDGGCYAVSVFART +REATRPTVDAAIGAAAGIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00048D4472 +------------DRTPGTVSASLGHLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE +AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL +PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGTLALGALAAPESCA +AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA +DPTDASPDDDACQLIADISARA- +>[subseq from] Beta-lactamase class A-like protein n=3 Tax=candidate division WWE3 TaxID=422282 RepID=A0A0G0Y287_9BACT +--KVETQFLELTKKLPGVYGLYIKDVGSGKEF-KYNESTEFYAASLYKVPIAAAVLKEVE +AGRLKLDDTATYLPYDYSSGTGVIGTYSHGILKISDILSELLKNSDNTAQNILLRTL-SY +KNVQETFNAV-----VPDKNTSTYY------RYNLSTPAEIGYVFEKLYFGDYLSADDKK +YLSDLMTNTSF-EDRISAYLKEGLVFSHKIGSWPD-SWHDCGVVYTENRESELMVCLMSQ +R---------------------- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium disporicum TaxID=84024 RepID=A0A174DS65_9CLOT +-----KEIKRYLESRIGTYGFFFEDLKSGYVY-GYNENVSMTAAGCMKLPIAVSLIKAVE +DGKVDFLDKIKIQSEDKVYGTGIIHEFNEREYTVFELLVIMLIQSDNTAANKIIDIL-GM +EKINQDILEMGLKNTKLNRKTTDERD-NHTDIENLTSAYDLNLIWKHLYNGTFLNKDNGQ +MLIDILRRQQI-KNKLALYLCDDYEISSKTGDKY-GVENDTEFIQLPKGD-FAFTVLSSG +LPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. CPC35 TaxID=2024880 RepID=A0A2D4YW83_9SYNE +---------LAAQQKDLQASAYMLILDDGRFA-QMNAERPMPAASAIKTPILLAALELID +SGELKWNEPLTLNKELVGGGAGWMASRPLGSFPTHEVATEMIRISDNSATNLLIARAGGK +EKINARFQAMNLPATVVNNWLPDLDGT------NTTSARXLSRAIALVDSGETLAPRSRD +LFXEVMATSVT-NTLLPTGLMRGYRVYNKTGDIGI-AYAXAGLIEMPXGRRAVAGFLVKG +PFN-DPRSTELIRRLASAMA--- +>[subseq from] Beta-lactamase class A n=2 Tax=Edaphobacter aggregans TaxID=570835 RepID=A0A3R9R114_9BACT +---LQQELAALVEKHHGKVALYATQLNTGKSV-AIDADRPVQTASVIKLTILFEAMEQVR +AGKARWDEKLTLVKGDGVSGSGVLTFFDTPLLTLKDVLTMMVIVSDNTATNLAIDRF-GV +DAVNARIAWMGLKDTHLYKKIGKPATDQPKFGLGKTTAREMAMVMERIGRCQAGDAAICE +VALKMLRNQFY-RETIPRYLETGSGIASKTGSLN-AVRADVAIVAGKTG-PMVLSIFTFD +NEDKDNEGEVLIGRLAKTIVEAw +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 04169 TaxID=2203197 RepID=A0A429C8P8_9PSEU +--EVTETISERAKEAGVRVRLHAAEIDGTRHI-GVDEHAPVVTASVFKVPIALELAKQGA +EGALDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILDRV-GK +EATEKTLRDLGFEHTTVSQDCGEVLRALQPEHTCATTAEEITRLLGLVWRDEAAAPAACA +DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] Serine hydrolase n=1 Tax=Tsukamurella pseudospumae TaxID=239498 RepID=A0A138AJ22_9ACTN +---ARERIEAVFADAGCNGWLHARVIGDGAEL-SVRGGQPVVPASVYKVVLLVAAARAVD +AGRLDPRARVVVDPATATPPTGLAALSDPVEMSVRDLLRSMVAVSDNAAAGVVMRLV-GL +DAVQMTARDLRLNDTRIVGGDAEIHAAYDPSFGSATTATDMTALLAAVWSDTAASAEQCA +FARSALGGQVF-RHRVASGFGSAPSIAGKTGTLG-ALRNEVAVVGYPGEHPVAVAVFTHA +ARPSLPLVDAAIGRVAAIAVD-- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A0Q8DDW5_9ACTN +----------------------------AGEV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL +DTVRLLAEELGLDRTRIVGGPRHVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA +RVRELMARQAF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART +REASRTAVDAAIGATARIAVDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Nocardioides sp. SLBN-172 TaxID=1813332 RepID=A0A542N9E5_9ACTN +----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD +RGLLSLDEPIAVHPDE--MQDPATWEAIGSSLPLGDLVRRSLTVSGNLAVNLVLERV-GL +AEVAAVLDDAGVTMTTVSRGIEDAPA-REAGLQNLVTANDMGKLLTKLASGRLLSPESTA +ELEGILVAQEY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIRPAQGEPQVMVVLTTG +LDD--DESEFRISEVARYLWS-- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=R4T8A4_9PSEU +--EVTETISERAKEVGVRVRLHAAEIDGTRQI-GVDEHAPVVTASVFKVPIALELAKQGA +EGALDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILDRV-GK +EATEKTLRDLGFEHTTVSQDCGEVLRALRPEHTCATTAEEITRLLGLVWRDEAAAPAACA +DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. WP24 TaxID=2604469 RepID=A0A5D0TPG3_9ACTN +--------------------------AGGREV-AVGADEQVVIASIFKILLVLEFARQVT +AGQLDPTERVLVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLARTRIVGGPRQLVEVFDPERTTSSTARDITGLLGLIWRDEAGPAAACA +MVRNWMARQLF-WTRLATGFPPGVRVAGKTGTLP-GLHMEAGVAEYPDGGRYAIAVFART +AQTRRIDVDLAMGEAARTAV--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL B-1347 TaxID=1476877 RepID=UPI0004CA2054 +----------------GAPGAAAAPVADGQAGvSVAADTPVALSSVFKVLLVLEFARQAA +AGQLDPRERVLVTDEHRLGGWGTAGCVDDVEISLRDLAYFALTVSDNSAADILLSRV-GL +DTVGLLARELGLARTRVVGGPREALAVLDPRRANASTPREVTRLLDLIWRDAAGPPEACA +QVRELMGRQVF-RHRLTSGFPDDVRIAAKTGTLP-GLHIEAGVVRWPEGDTYAVAVFARS +RAADLTRVDAAIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudonocardia sp. EV170527-09 TaxID=2603411 RepID=A0A5B0ID18_9PSEU +-----------------------------RDV-DAGAHAPVVMASVYKLFVLVAYCREVD +AGTVDPREPVVVPVPRTPGPTGISALADPVTMSWRDLVTSMVTASDNAAADVVHSRV-GR +DRVAALPAELGLSGTRIRGGTDDVFAALSPVYGSATTAADVTALLALLWRGELASEASTA +FARRLLGAQIW-PHRLRAGFPAPTQVAGKTGTVG-AVRNDVGVVTYPGEHPVAVAVFTHS +ARTTVPRADAAIGAAARVAVH-- +>[subseq from] Serine hydrolase n=1 Tax=Micromonosporaceae bacterium TaxID=1873464 RepID=A0A3D4WT02_9ACTN +---------EIFDKVGVDARLHVVDVDTGREV-GMRADEQVVIASVLKILLVLEFARQAV +AGQLDPTERVMVRATDRLGGWGTAGCADDVELSLRDLAYFAISVSDNTAADLLMRRI-GP +DVVPLLTAELGLIRTRVLGGPRQVLEVFDPAHTTSSTAREITRLLTLIWRDEAGPPAACA +MVRDLMARQMF-WTRLPSGFPPDVRVSAKTGTLP-GLHIEAGVAEYPDGGRYAIAVFAQT +QRLNTR----------------- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. SID8362 TaxID=2690346 RepID=A0A6B2DSX5_9PSEU +--------------------LHVRRLGSPAAT-GIGADSPVVLASVVKVPLAYEFARQVA +AGLLDPADRVRATAADRLGGTGSAGFADDVSYSLRDAARLALSVSDNTAADLLFDRV-GV +ANVRSLLAELGLTRTSVIGAPRDLLAALDPSRTSATTPREMTALLAAIWADPVAEP---- +-VREWMSAQVS-WHRLTAGFPPEVAVAGKTGTMP-GIRNEIGVATYPDGVSYAIAVFTVG +GAETRPDIDRAIGDAAHAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Pseudonocardia sp. P2 TaxID=882856 RepID=UPI0003086580 +---------------------------SDRDV-DAGAHAPVVMASVYKLFVLVAYCREVD +AGTVDPREPVVVPVPRTPGLTGISALADPVTMSWRDLVTSMVTASDNAAADVVHSRV-GR +DRVAALPAELGLSGTRIRGGTDDVFAALSPVYGSATTAADVTALLALLWRGELASEASTA +FARRLLGAQIW-PHRLRAGFPAPTQVAGKTGTVG-AVRNDVGVVTYPGEHPVAVAVFTHS +ARTTVPRADAAIGAAARVAVH-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. CNZ303 TaxID=2512144 RepID=UPI00104C6091 +--------------------------DGRREV-AVRADEQVVIASIFKVLLVLEFARQVV +AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA +DVLPMLAAELGLPRTRIVGGPRQLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACA +MVRGWMARQLF-WTRLATGFPPGVRVTGKTGTLP-GLHLEAGVAEYPDGGRYAVAVFVRA +TQTRRIDVDLAMGQAARAAV--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SID1034 TaxID=2690248 RepID=A0A6B1NVA8_9ACTN +-------ITAALTDAGLGGALCATDIDTGATV-ALAADTPVSTASVHKLCLVATLYREAA +AGRLDPTTPVDIPAGARAPPTGLAVMRDAARLSLRDLASLAVAVSDNAAADILWDHL-GL +DTVNATMNALGLTRTIAVHNQAGLYAVLDPARTNRSTPREITALLTAVWRDEVCDGAWGE +ELRAVLGVQAW-SHRLASGFPDDVRVSGKTGTLPT-QRHEAGVVEYPDGGRYAVAVFTRA +ASATLPAADAAIGRAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004C92F33 +----------------------------AREI-AVGADDAVVIASLFKILLVLEFARQVV +AGQLDPRERVRVTSADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLDRV-GL +DTVRLLAKELGLERTRVVGGPRDLLEVLDPRHTTASTPREITRLLRLVWTDAAGPPEACA +LVRDLMGRQVF-RHRLVSGFPDDVVVAAKTGTLP-GLHMEAGVARYPDGACYAIAVFART +HDASRATVDAAIGRAAGI----- +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC201 TaxID=1848320 RepID=A0A4R4NHC3_9ACTN +---------DHARELGADIWLHARDLATGRSV-GVGESTPVVTASVLKVPVALELARQSV +AGEVDLTERITVPPGGVPSPYGLSVQRDDTVISYRDLAHLMIVISDNVATDLVIGRV-GK +DRVAALLAELGLTATAVPQDCAEILAALVPERTCRTTPEEITRLLAGIWRDEAAPPEACA +LVRGWMGDQIW-PHRLTSGFPDDIVISGKTGTLPL-VRNEVGVVEYADGGRYAVGVFTRA +GDPNAPHLDALIGWAAAN----- +>[subseq from] Putative beta-lactamase n=1 Tax=Microgenomates bacterium 39_6 TaxID=1641391 RepID=A0A124FZA6_9BACT +-kELQEELLELIGQERGVYGVYLLAAESQNAI-GINHQKIFPGASLMKLPVIATAYQEAE +KGRFDLTAEYRLKEEDKLVGNGSVHLQPEGTYTYQALIQLAIEQSDNTAVSVLADNL-GK +EKIQALIDFSGLSRTDYLAGE--------------TTPEDIGQFLFSLHQGKMLTSSHSQ +EFIGFLTNTIF-NDQIPSVLPENLVVAHKIGLDEN-LLHDAAIIFTDKGD-FILVIMSQG +DSQD--RAQMILEEITKMIWK-- +>[subseq from] serine hydrolase n=1 Tax=Natronorubrum texcoconense TaxID=1095776 RepID=UPI000B7EE640 +----RSAAKRIDERLDGRLGMVVCDAGSTPLV-AIRPTERFGAASLVKLPILYALYRTYD +GRLADLDRPHSIAPENRVGGDGLFHLLSDPTPTTEDLATAMISVSDNAATNELIDHL-GF +DAIDEGAADLGLEGTRLGRKMMQTPASNGHRYVNWVTPRDCATLLSDIHGGRTLSSAAYE +RLARPLAHQHD-GSMVPRYLPPDVDILHKTGNLPS-VAADAGLLTVGER-TVAYAICCDG +LE-HRGEGVDAIAELSAGVY--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces fungicidicus TaxID=68203 RepID=A0A494UG99_9ACTN +---------------------------GGREV-AVGADDAVVIASLFKMLLVLEFARQVV +AGQLDPRERVRVTSADRLGGWGTAGCLDDVELSLRDLAYFAMSVSDNSAADLLLHRV-GL +DTVRLLAKELGLERTRVVGGPRDLLEVLDPRRTTASTPREITRLLRLVWTDAAGPPEACA +LVRDLMSKQVF-RHRLVSGFPDGVAVAAKTGTLP-GLHMEAGVARFPDGECYAIAVFART +HDASRATVDAAIGRAAGMA---- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. XY152 TaxID=1415560 RepID=UPI0006AF11F2 +----------------------------AREI-AVGADDAVVIASLFKILLVLEFARQVV +AGQLDPRERVRVTSADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLDRV-GL +DTVRLLAKELGLERTRVVGGPRDLLEVLDPRHTTASTPREITRLLRLVWTDAAGPPEACA +LVRDLMGRQVF-RHRLVSGFPDDVVVAAKTGTLP-GLHMEAGVARYPDGACYAIAVFART +HDASRATVDAAIGRAAGI----- +>[subseq from] Beta-lactamase class A n=1 Tax=Kitasatospora viridis TaxID=281105 RepID=A0A561SEL4_9ACTN +--AARARIADAFADAGVSGLLHARDLDGPAEL-AIGADTPVATASVHKLCLLTTLFREAA +AGRIDLTRQVEVPAAGRTGGPTGLAAMLDPALSLRDLAYLATAVSDNAAADLLWDEL-GL +DLVNRTMADLGLTRTVAVHRLRDLLAVLDPAATNRSTPRELTELLTAIWHDRACRGEHGA +ALRRLLGLQVW-PHRLASGFPDDVRVYGKTGTLPT-LRHEVGVVEYPDGGRYAVAVFTRA +AATSLPAADAVIGTAARLAVD-- +>[subseq from] Beta lactamase n=1 Tax=Streptomyces griseoflavus Tu4000 TaxID=467200 RepID=D9XN01_9ACTN +---------------------------GGREV-AVGADDAVVIASLFKMLLVLEFARQVV +AGQLDPRERVRVTSADRLGGWGTAGCLDDVELSLRDLAYFAMSVSDNSAADLLLHRV-GL +DTVRLLAKELGLERTRVVGGPRDLLEVLDPRRTTASTPREITRLLRLVWTDAAGPPEACA +LVRDLMSKQVF-RHRLVSGFPDGVAVAAKTGTLP-GLHMEAGVARFPDGECYAIAVFART +HDASRATVDAAIGRAAGM----- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ303 TaxID=2512144 RepID=A0A4R2B4E0_9ACTN +--------------------------DGRREV-AVRADEQVVIASIFKVLLVLEFARQVV +AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA +DVLPMLAAELGLPRTRIVGGPRQLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACA +MVRGWMARQLF-WTRLATGFPPGVRVTGKTGTLP-GLHLEAGVAEYPDGGRYAVAVFVRA +TQTRRIDVDLAMGQAARAAV--- +>[subseq from] serine hydrolase n=1 Tax=Oceanobacillus jeddahense TaxID=1462527 RepID=UPI0005963129 +--------------------------SGEEQI-AFNEKEQLRSASIIKLFILATAFYEQE +KGNLSLSEQVCIPPSEIVGGAGVIPYLSGEQYTYQQLLELMIIVSDNTATNALIDFI-GL +DNIHAFIQSIPCKHTKLERKLMDQ-DAIKAALENKTTCYDVMLLLDLFTEQNILPKHCQE +QILAILENQQF-NSKLTASYDSTIKTYHKTGELT-GAEHDAAIFQTSEIQ--LKAVMLTE +GWANNGEGQQFHQSAGAHIYRY- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis benzoatilytica TaxID=346045 RepID=UPI0003813D54 +---ATEKILRRANEIGVEVWLQAADVDGTATF-GIGADVPVVTASVFKIPVALELARQAA +EGLRDLGDRIAVRPGHPTPPYGLATFRHEVVMSWHELAILMIGISDNVATDLILAEI-GK +DSVNATLRRLGLARTAVPQDCAELLAALQPENTCRTTAAEMTRLLGLIWRDEAAPPQACA +DVRRWTGLQVW-PHRLRSGFPDGIRTSGKTGTLPS-VRNEVGVVEYPDGGRYAVSVFTRA +EDSRVPERDAFIGFAAATAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Caulobacter sp. BP25 TaxID=2048900 RepID=A0A2G4KFP5_9CAUL +-kALQKAMERLAARAPGVLGVAAEDLGTRQVW-AFNGDRPFVLGSAVRVPILAAVMADHA +AGRLDPNEVITVRDVDLSPPSAVADAWPGRKYTVAAL-EALARAGDNTALDLLAKRIGGP +GGVNGLLAVRQLEGISVDRYRRQAETRRAVDQRDTATPVGLVRLLEAFNTREVFASAEPR +LLLG----ND--PGYLATALPAGARIWQAAGANRNDESHAVALIELKDGRRVALAAFLSG +STANAAAREAILSEAGRTVLKSf +>[subseq from] serine hydrolase n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=UPI0009771D4C +------------------------------------------------------------ +------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM +TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNLLYQNR--DQAPYS +KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ +VQNPAAERQA-IGA--------- +>[subseq from] hypothetical protein n=1 Tax=Hungateiclostridium alkalicellulosi TaxID=320502 RepID=UPI0011E73EA6 +-------IDKHVKNLDKNIRISIYDFATNTSV-NYNGFDKFYPASLSKVLNLLCYLKEVE +KGNLSLYNTYTLKESDKYVESMVVQQEEGTQYSYNDILFRMISLSDNVAANIIIDAL-GY +NKINSLSKNYGLKDTMIYRKFYEMNSPVP---VNFSTAYDLTKMLVLLENRTILEDGLSN +IGIDFMKKTYN-KDRIALYAPDNVVIANKIGSLSR-LSGDMAIVYFENREPIALTIFVED +KNIDNQEVNHVIGELSKEVIDYy +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. e14 TaxID=645465 RepID=D6KD09_9ACTN +------------------------------------------------------------ +------------------------------------------------------------ +---TRLVRALGDPATRLDRTEPHVNDA--DGVLDTTTPAHLAADLRALTLGHALEARDRD +RLLAWLDASTTGDRAVRAGCPRGWRIGDKTGSGSHGESNDVAVIRPPHRAPLVLTVFTAP +ADPRSTAGQPTIAEAARIVA--- +>[subseq from] Beta-lactamase class A-like protein n=2 Tax=unclassified Microgenomates group (miscellaneous) TaxID=1794839 RepID=A0A0G0WWX4_9BACT +------------------YSILVVDTKSDFRV-AINDTEMFTAASVNKIPILAALYIGIQ +NTDIDPDTVITVQEEDIQDTGSIRYDGAGSTYTIKTLARLMMQQSDNTAAYILANHIIRL +DTIQSLLNEWGMTQTDMIN--------------NKTANNDVYKIIKKIYQGNIANPAYTQ +EMLAFFKDTEF-EDRIPGLLPKTVQVYHKIGSEI-GYMHDVGVVVAPSIT-YYIGIFTSD +IT-NEKEATKLMAEVSKLVYDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Clostridium algidicarnis DSM 15099 TaxID=1121295 RepID=A0A2S6FZK6_9CLOT +-----KEIKKYLESRIGDYSFYFEDLDGGYIY-GYNENVPMISAGCIKLPIAMAILKESE +IGNISLNDKLSVSIDDKVSGNGIIHEFEEKEYSLIELLIAMLIQSDNTATNKLVDLV-GM +SKINSIFKEMDLKSTKLNRRVEKEK-DVDSRIQNITSSYDLCLCWKHLYNSSYLNKENSN +WVIRIMKKQQM-KNKLAFYMGEEIKIANKTGDLS-GVENDTSFIQVPKGN-FAFTMMSKG +VPND-VYGIVTLAKSGKMMW--- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora kangleipakensis TaxID=1077942 RepID=A0A4Q8B9K5_9ACTN +----------------GNLHVVEVDGGAGREV-EVRADEQVVIASVFKILLVLEFARQAA +AGQLDPTERVLVRADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DVVPMLAAELGLSRTRIVGGPRQLVEVFDPAHTTSSTARELTRLLGLIWRDEAGPPAACA +TVRELMGRQLL-WTRLASGFPPGVRVAAKSGTLP-GLHLEAGVAEYPDGGRYAIAVSART +ERLDTRDVDLAMGEAARVAVE-- +>[subseq from] Beta-lactamase class A (Fragment) n=1 Tax=Streptomyces sp. SolWspMP-sol7th TaxID=1839776 RepID=A0A1C4Q503_9ACTN +-------------------VVHAVDIDRGTET-GWEADRLVCTASVHKLCLLLALHRLAA +AGRIDLTERVECPVEGRTPGTGLAAMLDAPRMSLRDLAYLMIAVSDNAAADLLLARV-GL +EEVNRTTEALGLRRTRAVESFAATQEALDPAHGNRSTPRELTRLLAALWRDEFLPEPHGA +AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA +ADT-------------------- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536A8A1_9CHLR +-qDLVRQLDGLVSGFAGGTGVWVSDPSSPTPLfTHAPDEQVITASLYKLGVLAEAERRVD +SGELHYNDPVLIAPEDVTSDGSFE--EAGTSLTLDEALESMITISDNGAALALWHILGGS +----------NIDVTLTKAGMADFHVAYDDSEDNWATPRALGTFFTLLAKRQLISAAASD +RMLARLERQQI-NNRLPAQLPPDVLIAHKTGNLP-GLTHDAGIIFTKAGPRVVVAMTWDA +LD---EDADSFISSVGALVY--- +>[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI000364FFDC +-----------LDRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE +AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL +PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA +AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA +DPTDASPDDDACQLIADISARA- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces spectabilis TaxID=68270 RepID=A0A516RM49_STRST +---------------------------ARADV-SVAADTPVAISSVFKVLLVLEFARQAA +AGQLDPRERVLVTDAHRLGGWGTAGCVDDVEISLRDLAYFALTVSDNSAADILLSRV-GL +DTVGMLARELGLARTRIVGGPREALAALDPQRANASTPREVTRLLDLIWRDAAGPPEACA +QVRELMGRQVF-RHRLTSGFPDDVRIAAKTGTLP-GLHIEAGVVRWPEGDTYAVAVFARS +RAADLTRVDAAIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. BL4 TaxID=2478710 RepID=A0A3L7B7U4_9ACTN +---------------------------GGPEV-GVRADEQVVIASIFKILLVLEFARQVV +AGQLDPTERILVTAADRLGGWGLAGCTDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLTRTRVLGGPRDLVEVFDPARTTSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAIFARA +DRPRRIDVDLAMGQAARTAV--- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis kentuckyensis TaxID=218823 RepID=UPI000A3BFFE2 +---------------------HAREIGGGPSV-AVGADDPVVLASVFKILVAVAYAREAA +AGRLDETARTRVGPRYRIGGIGTAGCADDVEMSWRDLALVMLTMSDNAATDVVYHRI-GA +AAVDRVPADLGLHRTRLIGCCEDLFAVLDPERTTSSTPREITELLDAVWTDRAGDPAACE +RVRSMLARQIW-PHRLSSGFPSDVGVAAKTGTLPS-VRNEAGVVSYPDGRRFAVAVFTRA +NSDRQPAIDAAIGRAGRLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis lexingtonensis TaxID=218822 RepID=UPI000A367519 +----------------VRGFLHVRRLGSPAST-GVGADAPVVLASVVKVPLAYEFARQVA +AGLLDPTDRVRASAADRLGGSGSAGFADDVSYSLRDAARLALSVSDNTAADLLFDRV-GV +ANVRSLLAELGLTRTTIIGPPRDLLRALDPLRTSASTPREMTALLAAMWGD-----PAGD +QVREWMAAQVS-WHRLTAGFPPEVAVVGKTGTMP-GIRNEIGVATYPDGVSYAIAVFTVG +GAETRPDIDRAIGDAARAAVEQ- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Amycolatopsis sp. M39 TaxID=1825094 RepID=A0A178XFM2_9PSEU +----RARIEAVFADAGAEGFLHAREIGPGPEV-SAGGDAPVVLASVFKIPVALAYAREVA +AGRLDDTERTKVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMGDNAATDVLYHRL-GQ +EKVDRVLADLELARTRLIGCCEDLFAVRDPERTTSSTPREITELLDAIWTDRAGEPQACE +RVRTIMAQQIW-PHRLSSGFPPGVAVAAKTGTLP-GIRNEAGVVTLGDGRRFAVAVFTRA +QSDRLPAVDASIGAAARLALDH- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora tulbaghiae TaxID=479978 RepID=A0A1C4VBS9_9ACTN +-----ERVAEIFGRAGLRGCLHVVDVDAGGEV-ALRADEQIVIASIFKIMLVLEFARQAA +AGQLDPTERVVVGPADRLGGWGVAGCADDVEISLRDLAYLAMSVSDNTAADLLLRRV-GA +DVLPMLAAELDLPRTRIVGGPRQLAEVFDPEHTSSSTARELTRLLRLVWRDEAGPAPACA +MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRT +ERARRIDVDLAMGEAARTAV--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces agglomeratus TaxID=285458 RepID=A0A1E5P1Q6_9ACTN +-----ERIREVFAGAGAEGLLHAVPVGTEEEV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAISVSDNSAADLLLARV-GL +DTVRLLAGELGLGGTRIVGGPRDVLEVLDPLRTNASTPREITRLLRLVWRDEAGPPEACA +HVRDLMMCQAF-RHRLVSGFPDEATVAAKTGTLP-GLHMEAGVVRYPDGGSYAVSVFART +RDASRPVVDAAIGASARIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2573 TaxID=2512224 RepID=A0A4R8C459_9ACTN +----NARIRAVFEDAGVRGWLHAVALDEPESTvEVDADGIVPLASVYKLPLLAGFCRLVD +LGEIDPRQQLTLDPSTKTSGPTGLSTFADPVASLRDLALSMMTLSDNASADALLDVV-RL +QRLAELLKSFGLQRTWVRRGTAGNLRVYEAANASAASARDMTLLLRRLWAGELLSPEQTE +FVKATMHRQVF-LHRLASGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGTAYAIAVFTLA +ARGDQPRVDAAIGEAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. OV198 TaxID=1882787 RepID=UPI000BD5DA38 +--------------------------GEAREV-AVGADEPVVIASIFKVLLVLEFARQAA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNAAADLLLDRV-GL +DTVRLLAKELGLDRTRIVGGPRDVLEVLDPLRTNASTPRETSELLRLIWRDEAGAPEVCS +HVRDLMSRQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMETGVVRYPDGGCYAVSVFART +REATRPRVDAAIGAAAAMAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 04197 TaxID=2203199 RepID=A0A429E8W5_9PSEU +--EVTEKITERAKEVGVRVRLHAAEIDGTRQI-GVDEHAPVVTASVFKVPIALELAKQGA +EGALDLGERITVPPGHPTPPDGLATFRHEITMSWYDLAILMIGISDNVATDLILERV-GK +EATEKTLRDLGFEHTTVSQDCGEVLGALQPEHSCATTAEEITRLLGLIWRDEAAAPAACA +DVRRWMDLQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Rubricoccus marinus TaxID=716817 RepID=A0A259TWE7_9BACT +-sELQSAVEKLARGFRGRVGVYVRHLPSGRSA-ALRADSLFPTASMIKVPILVATMEAIH +RGDLAWDEPLVFRDSLRYDDHGLIGLLRDSAIELHVAVEAMLSASDNNASLWLQSLSGGG +ARINEILAARGYTGTRMNSGTDGRRADWERYGWGQTTPREMSHLVREIVDRDIVSPQADE +RMHRALTRTFW-DGEALSAIPPGVQVASKQGAVS-ASRSEVLYVHAPSG-PYVFTVITDA +QEDQ------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. KhCrAH-43 TaxID=1305827 RepID=A0A327U430_9ACTN +-----TALRAAFTDAGVTGRMHALDIVSGAEL-DVCGDELVCTASIHKLPLLVTLHERAA +AGDLDLTEQTDCPPLGRPAGPTGLAAMLDVALSLRDLAYLMMAVSDNAAADLLLDRV-GL +DAVNRTAARLGLSRTIATHSFGEMMAALDPAWANRSTPRELTRLLAAIWRDEACTPENGD +AMRRLMALQVW-PHRLASGFPDDVHVAGKTGSLPT-LRGEAGVVEYPDGGQYAVAVFTRT +LSAIVPAADAVIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Natronorubrum texcoconense TaxID=1095776 RepID=A0A1G9D973_9EURY +----RSAAKRIDERLDGRLGMVVCDAGSTPLV-AIRPTERFGAASLVKLPILYALYRTYD +GRLADLDRPHSIAPENRVGGDGLFHLLSDPTPTTEDLATAMISVSDNAATNELIDHL-GF +DAIDEGAADLGLEGTRLGRKMMQTPASNGHRYVNWVTPRDCATLLSDIHGGRTLSSAAYE +RLARPLAHQHD-GSMVPRYLPPDVDILHKTGNLPS-VAADAGLLTVGER-TVAYAICCDG +LE-HRGEGVDAIAELSAGVY--- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora inositola TaxID=47865 RepID=A0A1C5H0L2_9ACTN +--------------------------GAGREV-AVRADEQVVIASVFKILLVLEFARQAA +AGQLDPTERVLVRAEDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DVVPMLAAELGLPRTRIVGGPRQLVEVLDPAHTTSSTARELTRLLGLIWRNEAGPPAACA +MVRALMGRQLF-WTRLASGFPPGVRVAAKSGTLP-GLHLEAGVAEYPDGGRYAIAVSART +ERLDTRDVDLAMGEAARVAVE-- +>[subseq from] serine hydrolase n=1 Tax=Tsukamurella sp. 1534 TaxID=1151061 RepID=UPI000A30DE79 +-----EEIAAVFADAGCNGWLHARVVGHPARL-SVGGEQPVVPASVYKLVLLVAAARAFD +AGRLDPLERVTVDPRTATPPTGIAALDDPVEMTLRDLLRTMVAVSDNAAAGTLLRRV-GL +DAVQATATALGLADTRITGGDAELYAAYDPSFGSATTAADATALLAAVWSDAAASPEQCA +FVRSALAGQTF-RHRVASGFGSAARIAGKTGTLG-ALRNEAAVIAYPDEHPVAVAVFTHA +ARPSLPRVDSAIGEVAAIAVN-- +>[subseq from] Uncharacterized protein n=1 Tax=marine metagenome TaxID=408172 RepID=A0A382FFM2_9ZZZZ +--ALENELNQLCDEQPFHTGWSVKNLRTGTVL-ERHGSVVVPSASTRKIAIMMAALKAVN +EGELSLSQPVTMASRFKNNDSGCFQHLQSDFIQLQDALVMMIIVSDNTCTGAVADLV-GL +EAINALCQSIGMADTVHRYGIPGMAGYLPAEKTNSTTPADVARLLELILKGVGCTSELCQ +LAIDILSWQRL-RNRIPARLPLGTKVAHKTGTTAK-NYNDAGIVYADGVPLFLISAYTDS +VPVE------------------- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora terminaliae TaxID=1914461 RepID=UPI0012AEC86B +-----ERIGEIFERAGISGCLHVEDVDPGRAV-ALRADEQVVIASVFKILLALEFARQVV +AGQLDPVERVLVGAGDRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DVLPMLAAELDLPRTRIVGGPRQLVEVFDPAHTTSSTAREMTRLLGLIWRDEAGPPTACA +MVRELMARQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVVEYPDGGRYAVAVFART +ERLSTRDVDLAMGEAARAAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora lupini str. Lupac 08 TaxID=1150864 RepID=I0KXI6_9ACTN +----------------------------DRQV-GVRADEQVVIASIFKILLVLEFARQVD +AGQLDPTERVLVTAADRLGGWGLAGCADDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP +DLLPMLAAELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA +DEPRRIDVDLAMGEAARTAV--- +>[subseq from] serine hydrolase n=1 Tax=Jiangella alkaliphila TaxID=419479 RepID=UPI00128D2EA7 +-----------------TGFLHAVDVGSGVEV-GVEPDAPVVTASVFKVSVLVELCRQFA +TGEREPADRLRVPAGARTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR +DRINALMVELGLPGTVLEEDCAGLFRVLDPRTTNRSTPRETTTLLRRIWAADGLPAAAGE +EIRRIMALQVW-PHRLTSGFQDDVKVSGKTGTLSH-VRNEVGVVEYPDGATFAVAVFLRL +PGGENPAADAVIGTAARIAVDH- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. SID8362 TaxID=2690346 RepID=UPI0014153069 +---------------------HVRRLGSPAAT-GIGADSPVVLASVVKVPLAYEFARQVA +AGLLDPADRVRATAADRLGGTGSAGFADDVSYSLRDAARLALSVSDNTAADLLFDRV-GV +ANVRSLLAELGLTRTSVIGAPRDLLAALDPSRTSATTPREMTALLAAIWADPVAEP---- +-VREWMSAQVS-WHRLTAGFPPEVAVAGKTGTMP-GIRNEIGVATYPDGVSYAIAVFTVG +GAETRPDIDRAIGDAAHAAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Bifidobacterium psychraerophilum TaxID=218140 RepID=A0A087CGN2_9BIFI +----------SAQAKGITVGATFQDLSGGGSLsAGAHGQAFKAASTIKLGITSYLMHGVD +QGKWSLDTPITVESSDVVGGAGTIQSDVAALFTLSELMRLMITVSDNTATNRLIDFAGGF +DKINAYTQSVGDSGFHLGRKMILPHTA---EEENWISSDEDAKLLTLIYRGGIISQESAK +QVIAWMRQQTV-NTKFGAVIPRE-VLANKTGENTD-VSHDTGYVLVPGRE-VALSVMTSF +DPTAFNTANEQVQAVAKVVYQY- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI00068E3B00 +------------------------------EV-AIGADDQVVIASIFKVLLVLEFARQVV +AGQLDPRERVRVSAADRLGGWGTAGCLDDVDLSLRDLAHFAMSVSDNTAADLLLARV-GL +DTVRLLAQELGLRRTRIVGGPRALLEVLDPRRTTSATPREITRLLRLIWTDAAGPPEACA +LVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVARYPDGALYAITVFART +HDASRPTVDAAIGRAAGIA---- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. me109 TaxID=1827853 RepID=UPI0011CD91CA +-----------------------------REV-AVGADQPVVLASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNAAADLLLDRV-GL +DTVRLLAEELGLGRTRVVGGPRDVLEVLDPLRTNAGTARETTRLLRLIWRDEAALPEACA +QVRDLMSRQVF-RHRLASGFPGDTVIAAKTGTLP-GLHMEAGVVRYPDGRCYAVSVFART +RRVTGPEVDAAIGRAARIAVE-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium ventriculi TaxID=1267 RepID=UPI00073F07A3 +-----KEVEKYLKSRTGKYGFFFEDLYSGYSY-GYNENVKLISAGCMKLPIAVALMKCEE +EGNIDYLQKIRVNSSDKVYGTGIIHEFGEKEYTVFELLVAMLIQSDNTAANKIIDIV-SM +DKINETIKELGMINTKLNRKTADERN-YISGIENYTSAKDLCILWKNLYNKTYLNENNSQ +MLIDILARQQI-KNKLALYITDDYEISSKTGDKK-GVENDTALIHTNKGD-FTFTVMSSD +IPNS-VYGTITLAKTGKMIWD-- +>[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00038131BA +------------DRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE +AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL +PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA +AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA +DPTDASPDDDACQLIADISARA- +>[subseq from] serine hydrolase n=1 Tax=Bacillus gottheilii TaxID=859144 RepID=UPI00082ABC5F +--QFNRDVQRLTSAAHGRVSLFIES--DKGVI-EKDRHAVYPAASTIKIPILLEALRQAE +SGEIDLKQSISISPAHITGGAGILQSLYHPTMKLVDLLSLMIVVSDNSATNIIIDLL-GQ +NQIKQCINIMNLQETKLQRKMMDFEAG-RRGFENTTSAYDLGICLKFLTEDGLLNEESRA +LGLEIMGRQQF-RKLAYSVTSSKIAVYGKTGELP-GVSHDCVILKKEHHL-LYGVALI-- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SDr-06 TaxID=2267702 RepID=A0A367HJQ1_9ACTN +---VRSRLTAALTDAGLTGSLCATDIDTGDDI-TLAADTPVSTASVHKLCLVATLYREAA +AGRLDPSTPLDIPAIGRAPPTGLAVMRDAARLSLRDLASLAIAVSDNAAADLLWDHL-GL +DTVNATMAALGLHRTIAVHNQAALYAALDPARTNRSTPREIAALLTAVWRDDVCEGPWGE +ELRAVLGVQAW-SHRLASGFPDDVRVSGKTGTLPT-LRHEAGVVEYPDGGRYAVAVFTRA +ASATLPAADAAIGRTARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Terrilactibacillus laevilacticus TaxID=1380157 RepID=UPI00114086B4 +-----EKLDRLVSPFGNKVSVVIQE--GKNHY-SFNESTKMLSASLIKLPIFLYAFDQVI +KGTLSLDQKIPISPEKMVDGSGIIQVIQDVRWSIRDLLGLMINVSDNTATNVLMDVL-GI +EQIQSWIENSGLNGTSIQRKMMDIQAK-KEGKENFTCASDVSQCMELIFLRPNSLSCEFP +FVKHYFLNQQF-RGKIPGKIESPVKIYNKTGEME-GISHDTAFMKLKDKT-SIVTCMTSG +FE-DATEADQLIQKMGEWVY--- +>[subseq from] Beta-lactamase n=2 Tax=Prochlorococcus sp. MIT 0601 TaxID=1499498 RepID=A0A0A2BHV3_9PROC +---------------------AYLNFEDGRYA-QLNAENSLPAASSIKVPILLIALEMLD +NKLLSWDELIELKRDLIASGSGWMRQRIGQKFPIHEIATEMIRVSDNTATNLLIDRIGGI +EILNKRFIELGLNQTHIKNMLPDLNGT------NRTSAKDLCQVFQIADSTNFLSLKSRD +LFREILSTSKT-NSLLPDGLLNGYRVYNKTGDIGI-SYADAGLIEMPDTSRATSAFIVKG +PFN-DPRSATLIRDLSAEIINH- +>[subseq from] Beta-lactamase n=2 Tax=Salinispora arenicola TaxID=168697 RepID=A8LX03_SALAI +------------DRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE +AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL +PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA +AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA +DPTDASPDDDACQLIADISARA- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. MBT27 TaxID=1488356 RepID=UPI001423FDE5 +-------ITAALTDAGLGGALCATDIDTGATV-ALAADTPVSTASVHKLCLVATLYREAA +AGRLDPTTPVDIPAGARAPPTGLAVMRDAARLSLRDLASLAVAVSDNAAADILWDHL-GL +DTVNATMNALGLTRTIAVHNQAGLYAVLDPARTNRSTPREITALLTAVWRDEVCAGAWGE +ELRAVLGVQAW-SHRLASGFPDDVRVSGKTGTLPT-QRHEAGVVEYPDGGRYAVAVFTRA +ASATLPAADAAIGRAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus selenatarsenatis TaxID=388741 RepID=UPI0014354C59 +---------------------------EGEMI-EFNSNEVYQSASLIKLPILFEALRQME +AGQLQKESQLPIEEGDKIGDTGVLQAMKVKQLPVVDLMSLMIIVSDNSATNLMIDLL-GK +DSINATISRLGMSHSILQRKMLDFS-AIQSGLDNYTSAADIGLCLKEGVKGDLLNQDSKS +IFHAFLLQQQF-KEKLPFYMDDTLEIGNKTGELP-GVEHDCGIIAYGEN-EAIIVVLIDE +LSNP-QSGKSTIQQIGKHI---- +>[subseq from] Uncharacterized protein n=1 Tax=Actinobacteria bacterium TaxID=1883427 RepID=A0A6A8N275_9ACTN +---LDSEVARIAERCSGVLGVEAWNLNGEEKV-SFNSKELFPTASVIKLPILVALYSQVM +MNEVDLSERIDIDVRQHLGGSGILKVFESGLPTIKDVATLMIVLSDNTATNLILDVVGGV +DPVNSLMESLGFPSIRLHNRIDFEAIGSDIRRLGESSAVEMCELNYRIAKGELLSPAISE +EIESILEQQQY-LNQFPRYMQPKIRVSCKTGFFM-GTRVDAGIVRFNGGGGFVYSVFNNE +CE--------------------- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Micromonospora sp. MH33 TaxID=1945509 RepID=A0A2P8AT53_9ACTN +-----ERIGEIFQRAGISGCLHVVDVDPGREV-ALRADEQVVIASVFKILLVLEFARQAV +AGQLDPAERVLVGAADRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DVLPMLAAELDLPRTRIVGGPRQLVEVFDPAHTTSSTAREITRLLGLIWRDEAGPPAACG +MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVVEYPDGGRYAVAVFART +ERLSTRDVDLAMGDAARAAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter mallensis TaxID=652787 RepID=A0A1H2A6N4_9SPHI +-sKLTKKLNALAKDFHGQVGIYVQNLKTGKSA-EVNADTLFPTASMIKVSIMCGLMDKIQ +KGELDYHQNLIFKDSLRYDTGDILGSVKNNDIALSKVAMLMITMSDNTASLWLQKLV-TG +EYINNWLQQNGFDNMRVNSRVKGRERIRSIYGWGVTTPREMCKLFTMIREGKAVSPAASE +RMYRNLSHIYWDDNAI-SQVPPYIQTASKQGFVD-ASRSETVLASAPHGN-YVFSIITNH +QKKHDNEGFILIRNVSALLWHYf +>[subseq from] serine hydrolase n=1 Tax=Streptomyces griseoplanus TaxID=66896 RepID=UPI0006E41FA7 +------------------------------EV-AVGADDAVVIASIFKILLVLEFARQVA +AGQLDPRQRVRVTSADRLGGWGTAGCLDDLELSLRDLAYFTMSVSDNSAADLLLDRV-GL +DTVRLLAKELGLDRTRIVGGPRDLLEMLDPAHATASTPREITRLLQLVWTDAAGPPEACA +FVRDLMSKQVF-RHRLASGFPDDVVVAAKTGTLP-GLHMEAGVARYPDGACYAIAVFART +HDTSRASVDAAIGRVAGIAA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Prochlorococcus marinus (strain MIT 9211) TaxID=93059 RepID=A9BB54_PROM4 +---LSKKWKELADEYDLEVSAYIL-FEDGRYA-QFNAEKSLPSASTIKIAILFLSLEMLD +DGKLRWDEEIELTKESIAKGAGWMRQSLGKKFPIHEITTEMIRVSDNTAANLLIERVGGL +DILNKRFKELGLMQTEINSLLPDLSGT------NKTSAKDLSKIMKLVDVSGLLSTKSRD +IFREVMSTSIS-NNLLPEGILKGFRVYNKAGDIGI-AYGDAALIEMPNSSRAVTALLVKG +PFND-QRSTNLIRDMAAQIIS-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium RIFCSPHIGHO2_01_FULL_40_15b TaxID=1798594 RepID=A0A1F6I7B2_9BACT +--SLKETVDSSLKGTHGTYAVIIKNLRTGEYF-SQNEKRTYEPASLYKLWVLGAAFKQIK +EGKLNRDEIISRDARDLNEASDSAELTEGTVMKISDAIEQMITISHNYAALLLVSKI-RN +SNVSAFMREQGFSSSRLGQPP-------------RTTAEDIASFFEKLYTGAMVDGEYSK +RMLDLLSQQRL-NDRIPKYLPDDVEVAHKTGEIR-GFKHDAGIIFAKD--PILLVVLSES +NS--QQGAAERIAQLSKNVYYYf +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC310 TaxID=1848322 RepID=A0A4R4W4Z5_9ACTN +----------HARELGTDIWLHARDLASGKSV-GVGETTPVVTASVLKVPVALELARQSV +AGEIDLSERVTVPPGGVPSPYGLSVQRDHTVVSYRDLAQLMIVISDNVATDLVIDRV-GK +GRVAALLAELGLTATAVPQNCAEILAALVPEETCRTTPEEITRLLAGIWRDEAAAPEACA +LVRGWMGDQIW-PHRLTSGFPDDIVISGKTGTLPL-VRNEVGVVEFADGGRYAVGVFTRT +DDPNAPHLDALIGWAAAN----- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces resistomycificus TaxID=67356 RepID=A0A0L8KXU2_9ACTN +------------------------------EV-AVGADDPVVIASIFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLARV-GL +DTVRLLAKELGLERTRIVGGPRDLLEVLDPRHTTASTPREITRLLRLVWTDAAGPPEACA +LVRDLMGRQVF-RHRLVSGFPDDVVVAAKTGTLP-GLHMEAGVARHPDGACYAIAVFART +HDASRPTVDAAIGRAA------- +>[subseq from] Serine hydrolase n=1 Tax=Acidithiobacillus sp. TaxID=1872118 RepID=A0A2G2KE75_9PROT +--TLENELNQLCDEQPFHTGWYVKNLRTGAVL-ERHGNAVVPSASTRKIAIMMAALKAVN +EGELSLSQPVTMASRFKNNDSGCFQHLQSDFIQLQDALVMMIIVSDNTCTGAVADLV-GL +ELINVLCQSIGMVDTVHRYGIPGMAGYLPADKTNSTTPADVALLLEIILQGVVCTPDLCQ +LAIDILSWQRL-RNRIPARLPLGTKVAHKTGTTAK-NYNDAGIVYAGDKPLFLISAYTDN +VPAXHTVAYDLTARLSRLCWDE- +>[subseq from] Beta-lactamase class A n=4 Tax=Candidatus Woesebacteria TaxID=1752722 RepID=A0A0G0L4F0_9BACT +--NVLSKFEESTDRLTGVYGLYVTDLASGHSF-GIYENNTFQAASLIKLPVMVGMYMSEE +DGALSLNTRYILKTEDKVRGSGSLYNKPAGYISYRDLLKLMGKESDNTAFNICRKHL-GD +EKIQDIINGIGMKGTSLEK--------------NETTPADIGSFFYKLWNGQLLNMKNTD +ELLINLTDTSY-EDWLTAGVPESIRVAHKYGRET-GVVNDAGIVYSENP---YIAVMLGK +NV-VLKEADSIFPELSKIIYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Clostridium saccharobutylicum DSM 13864 TaxID=1345695 RepID=U5MS21_CLOSA +-----KEIKQYLESRIGTYSLFFEDLQGNYSY-GYNENVQMTGAGCIKLPIAVSVIKYVE +DGKASFLDKIKIEDNDKVYGTGILHEFNNREYTLFELLVAMLIQSDNTAANKFISIV-GK +DRINQDIAAQGLKNTKLNRKTSDESEE-DNRTENITTALDLSKIWKHLYNASFLNRENST +MLIDILQRQQM-KNKLALYIPDDYEISSKTGDKSN-VENDTALIRTKKGA-YTFTVLSMG +VPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Beta-lactamase n=1 Tax=[Flexibacter] sp. ATCC 35103 TaxID=1937528 RepID=A0A1S6WDX2_9FLAO +-dKMKTEILEIIKGKKFNIGISVRNSKGVEIF-AHNSNEKYKMYSVSKFFLALKVLHLID +NKTLLLNQDVSFAKSDLKAFSPLRDSNPEGIITLEKALYYIVNQSDNNVFDKLVDLSGGI +ESLNFYISSFTKNKNSF--SMSALYRDKEGTGNNVVTPNFSSLLLYKLMKNKIISVESKN +ILMPLLETSIN-NKRIQALVPKNLKSFHKGGTSDRVASNDIGIVYINEKDFFTIAVFISN +SLEDDAVNDEVIAKITEIT---- +>[subseq from] Serine hydrolase n=2 Tax=Clostridiales TaxID=186802 RepID=A0A3A9HSQ8_9FIRM +------------EALGEKWAVSAVDLADGAVY-GYYEDIKMQSASVIKVFIMATVYDRVC +------------YPKDTESAIYVQEQYEG---ELKALLTNMITVSDNDAANRLVELLGGQ +EVVNAFCRENGFEGTSLGRRFLEENPA----DDNYTTSGDCMKLLQDLYNGNCVCAEASE +KMLNMLKNQTR-TEKIPSGIPEGTVCANKTGEMPQGIENDIAIVYGEHGD-YILCVLSND +LDGRNEEAKKRIAEISGYVYEEf +>[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. TaxID=1506 RepID=A0A355D766_CLOSP +-----KEIKRYLETREGEYSFYFADLKSDYTY-GFNEDLKMVAAGCIKLPIAMAVMKEVV +NTNIFLDQLVTITNDDKVSGSGIIHELEGRQYSIKELIVAMLIQSDNTAACKLINTI-GK +DRINSIIHDMGLTSTFIKKYPSGEKED--FDNENITTSYDLCKGLALLSKGKVLNGEHSK +FILEVIRRNQL-TTGISFYWPKDVKTAHKAGSLEK-IENDIVLLNLEKGD-FVFVVMSRN +LP-SNVYGVSSLARVGKMMVD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces violaceoruber TaxID=1935 RepID=UPI000998322E +------------------------------------------------------------ +---------------------------------------AAARQRHNTATNLPLDLLGGP +TAATAFASGLDDATTRFDRNEPQLNSTGPDDERDTTTPAAIVESMRAVPLAGGLQPAGRE +RLTTSLVVNTTGDATIRAGVPAGWLIGDRTGTGAQGERNDVGIVLPPDRAPLV------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora coriariae TaxID=285665 RepID=A0A1C4V256_9ACTN +-------------------------VAGGREV-GVRADEQVVIASIFKILLVLEFARQVV +AGQLDPTERIQVTAADRLGGWGLAGCTDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLTRTRVLGGPRDLVEVFDPARTTSSTAREITRLLTLIWRDEAGPPQACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYLDGGRYAIAVFARS +DRLT------------------- +>[subseq from] Beta-lactamase class A n=2 Tax=Micromonospora citrea TaxID=47855 RepID=A0A1C6UH25_9ACTN +---------------------------RRREV-AVGADEQVVIASIFKILLVLEFARQVV +AGQLDPQERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA +DVLPMLAAELGLPRTRIVGGPRQLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACA +MVRGWMGRQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAVAVFARA +AQTRRIDVDLAMGEAARVAVE-- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. HH130629-09 TaxID=1641402 RepID=A0A0M3UC36_9PSEU +---------------------------SDRDV-DAGAHAPVVMASVYKLFVLVAYCREVD +AGTVDPREPVVVPVPRTPGLTGISALVDPVTMSWRDLVTSMVTASDNAAADVVHSRV-GR +DRVAALPTELGLPGTRIRGGTDEVFAALSPVYGSATTAADVTALLALLWRGELASEASTA +FARRLLGAQIW-PHRLRAGFPAPTQVAGKTGTVG-AVRNDVGVVTYPGEHPVAVAVFTHS +ARTTVPRADAAIGAAARVAVH-- +>[subseq from] Beta-lactamase n=1 Tax=hydrothermal vent metagenome TaxID=652676 RepID=A0A160TR48_9ZZZZ +---LENELNRLCDEQPFHTGWYVKNLRTGTVL-ERHGSIVVPSASTRKIAIMIAALKAVN +EGELSLSQPVTMASRFKNNDSGCFQHLRSDFIQLQDALVMMIIVSDNTCTGAVADLV-GL +EAINALCQSIGMEDTVHRYGIPGMAGYLPADKTNSTTPTDVALLLEIILGGAGCTSELCQ +LAIDILSWQRL-RNRIPARLPLGTKVAHKTGTTAK-NYNDAGIVYTDDVPLFLISAYTDS +VPADHTVAYDLTARLSRLCWDE- +>[subseq from] Serine hydrolase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=A0A1S1M1R3_MYCCH +-----------------------------PIV-DVDGDRPAVAASVYKIFVLIAAARAFD +SGHLHPEATVRVAPADCTPGPTGISTFSNPVLTWLDLARLMITHSDNTAADVLLAAI-GL +DTVNELTEELGFNSTRIIGGTSALQRAFDPAYTTATSACDTDRALSAIWTGTATSAQSSD +MMKQILTQQIW-QHRIRSAFPRDVTVAGKTGTIGP-IRNEVAVIAFPGEPPMAVSVFTRA +ARADLPNVDRAIGQAARIAI--- +>[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00037C8C86 +------------DRVSGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE +AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL +PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA +AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA +DPTDASPDDDACQLIADISARA- +>[subseq from] Serine hydrolase n=1 Tax=Actinosynnema sp. ALI-1.44 TaxID=1933779 RepID=A0A1V2PK24_9PSEU +---VVETINDRAKEVGVRVRLHAAEIDGTRQI-GIDEGVPVVTASVFKVPIALELARQGA +EGELDLGERITVAPGHPTPPYGLATFRHEVTMSWHDLAILMIGISDNVATDLILAGV-GK +EAVGESLRRMGFEHTTVTSDCREILDALRPEHTCATTAEEITRLLAMIWRDEAASPTACA +DVRRWLELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVIEYPDGSRYAVGVFTDA +VDSRVPERDAFIGFAAARA---- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. or20 TaxID=1828016 RepID=UPI000BF00F2E +----------------------------AGEV-SVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL +DTVRLLAEELGLGRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA +QVRELMARQIF-RHRFVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART +REASRTAVDAVIGATARIAVDH- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces olivochromogenes TaxID=1963 RepID=A0A250VI06_STROL +---------------------------EAREV-AVGADEPVVIASIFKVLLVLEFARQAA +AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNAAADLLLDRV-GL +DTVRLLAKELGLDRTRIVGGPRDVLDVLDPLRTNASTPRETSELLRLIWRDEAGAPEACS +HVRDLMSRQAF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGCYAVSVFART +HEATRPTVDAAIGVAAAIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Clostridium sp. Maddingley MBC34-26 TaxID=1196322 RepID=K6U0Y4_9CLOT +------EIKRYLESRIGTYSFFFEDLESGFSY-GYNENVQMTAAGCMKLPIAVSVIKYVQ +DEKGSFLDKIKIEEEDKVYGTGILHEFDNREYTLFELLVAMLIQSDNTAANKLIDIV-GM +DNINEDIIAQGLKNTKLNRKTSDERAA-SSGIENITSALDLAKIWKHLYSASYLDKKNST +MLIDILQRQQM-KNKLALYIPDDFEISSKTGDKAS-VENDTALIHVQKG-SFTFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Serine hydrolase n=4 Tax=Corynebacteriales TaxID=85007 RepID=A0A1C2B1B4_NOCFR +---LDRAVHETFADAGCSGCVHVRTIGTPVEY-CHDADTPVVLASVYKLAVLVSLCRMAD +RGDIDLTASISVDPTRWAQGPTGLALFSDPVISWRDLATSMMTVSDNVAADVILAHI-GL +PQIHDDLVDLGLTHTRIVGGVAESHAAYDAAYSSAATPRDCTTLLDAIWTDRAASATSCE +FIRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AVRNEIGVIEFPGEVPIAVAVFTMS +ARSELPEVDRAIGEVARVIVT-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1DVJ7_9ZZZZ +-eRLKKQIEGIIHGTEGEVGVAVKHLESGQEL-YINGDINFPMASVFKVPILVEVLAQIK +EGKFALKDEISIQKTDQHLGSGMLSDLEAPGLSLRNLITMMMIISDNSATDILLTKV-GA +ENVNDRLRSYGIREITVNRTCQHLIMKFSQITKDQSTPRAMNRLLEMIYKK--------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Aminicella lysinilytica TaxID=433323 RepID=A0A4R6Q7A1_9FIRM +-----------IKKIPGRSGLYYKNLVTNEVL-AYNETEEFHPASMIKLPVFMAISKMVA +EGKARWNDKIKITYDVRVPSCGAFNAFTDEPVDVKTLCNLMITISDNTAANVLISHF-GI +DRLNGEFAATGLEKTHLERLFYDDEMQ-AKGFNNKAVPAELGGLLEKLHRKTFVNEKVSD +EVLAVLYDQQD-KCYIPEWFEDECPVANKTGGAR-GILGDEALVQTD--KPFVLVMMFNE +TV--TPEAAEFMRHAGKQLY--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces prasinus TaxID=67345 RepID=A0A5J6H197_9ACTN +---------------------------GGREV-GVGADDPVVIASIFKVLLVLEFARQAA +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLDRV-GL +DTVRLLAAELGLERTRIVGGPRDLLEVLDPRRTTASTPREITRLLRLIWTDAAGPPEACS +LVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRHPDGECHAVAVFART +HA-LAASRPTVDAAVGRAA---- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. WAC00469 TaxID=2487415 RepID=A0A429NCM4_9ACTN +-------IAADWAVLGMRGSFLARRLDTGEQL-GFDIDDPVPLASVVKVPFALVVLDRIA +AGLLDAAQPVTVDPATSSVGSTGLAARHPATVAVGDLLALMLAVSDNAAADALFDLV-PP +EETDARLREWGCTDIRVRHRMQRMYETLDPAHANAGTARGLVDLLQRVWQDEIARPAATA +ELRRLMAAQVF-THRLAGDLRDTIRVSGKTGTFLH-LRHDIGVVEADSGHRVAMAALTRS +DRALAPDIDAAIAAAARQAF--- +>[subseq from] serine hydrolase n=1 Tax=Clostridium algidicarnis TaxID=37659 RepID=UPI0004966C3D +-----KEIKKYLESRIGDYSFYFEDLDGGYIY-GYNENVPMISAGCIKLPIAMAILKESE +IGNISLNDKLSVSIDDKVSGNGIIHEFEEKEYSLIELLIAMLIQSDNTATNKLVDLV-GM +SKINSIFKEMDLKSTKLNRRVEKEK-DVDSRIQNITSSYDLCLCWKHLYNSSYLNKKNSS +WVIRIMKKQQM-KNKLAFYMGEEIKIANKTGDLS-GVENDTSFIQVPKGN-FAFTMMSKG +VPND-VYGIVTLAKSGKMMW--- +>[subseq from] serine hydrolase n=1 Tax=Clostridium mediterraneense TaxID=1805472 RepID=UPI00082E4587 +-----KEIQDYLRSRMGNYSFFFEDLRSGYVF-GYNENVKMTAAGCMKLPIAIALIKKEE +DGELSFLDKVKIEKEDKVYGTGIIHEFNEREYTIFELLVAMLIQSDNTAANKIIDIL-GI +DKINETIKLLGLKNTVLNRKVTDE-RNKDDDIENITTAYDLGQLWKILNNSTYLNENNST +MLIDILTRQQK-KNKLALYLQDDFKISSKTGDKK-GVENDTELIKLNKGT-FSFTVMSNN +IPNS-VYGTVTLAKSGKMMWD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. SLBN-134 TaxID=1081603 RepID=A0A542WM24_9ACTN +---------------------------GGHEV-AVGADDAVVIASLFKMLLVLEFARQVV +AGQLDPRERVRVTSADRLGGWGTAGCLDDVELSLRDLAYFAMSVSDNSAADLLLHRV-GL +DTVRLLAKELGLERTRVVGGPRDLLEVLDPRRTTASTPREITRLLRLVWTDAAGPPEACA +LVRDLMSKQVF-RHRLVSGFPDGVAVAAKTGTLP-GLHMEAGVARFPDGECYAIAVFART +HDASRATVDAAIGRAAGMA---- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora aurantiaca TaxID=47850 RepID=A0A1C6T291_9ACTN +---VAERIGEIFGRAGVRGCLHVVDVDAGGEV-ALRADEQIVIASIFKIMVVLEFARQAA +AGQLDPTERVLVGAADRLGGWGVAGCADDVEVSLRDLAYLAMSVSDNTAADLLLRRI-GA +DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEHTSSSTARELTRLLRLVWRDEAGPAPACA +MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRT +ERARRIDVDLAMGEAARTAVD-- +>[subseq from] serine hydrolase n=1 Tax=Gordonia terrae TaxID=2055 RepID=UPI0013F5F719 +-------------DAGCSGCVHVRTIGTPVEY-CQHADTPVVLASVYKLAVLVSLCRMAD +RGDIDLTASITVDPTRWAQGPTGLALFSDPVISWRDLATSMMTVSDNVAADVILAHI-GL +PQIRDDLVDLGLTHTRIVGGVAESHAAYDAAYSSAATPRDCTTLLDAIWTDRAASAASCE +FIRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AVRNEIGVIEFPGEVPIAVAVFTMS +ARSELPEVDRAIGEVTRVIVT-- +>[subseq from] HTH lysR-type domain-containing protein n=1 Tax=Propionibacteriaceae bacterium NML 130396 TaxID=2016507 RepID=A0A255HBS8_9ACTN +------RILDLWAGVEIEGAVHVRDLDSAAEL-GIDSDESWPLASVAKVPLAVALHRAAE +RGLVDLDQPRVLRPDGRTRTTGISAMSDSVTMSLRDAAYLALTISDNAAADAIWDAI-GA +DRIRASLREVEPGEVWLGEPTRDLYDAVDGPRACRATPRGATRLLARIWADEAASAPGCA +HLRDLMQRQVW-THRLASGFPEDIVVAGKTGTVQD-HRHEIGVVTYPDGSRYAVAVFSRR +RDRAAHHRDWAIGETARLAVN-- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis keratiniphila subsp. keratiniphila TaxID=227715 RepID=A0A1W2LT90_9PSEU +--EVTEKINERAKEVGVRVRLHAAEIDGARQI-GVDEHAPVVTASVFKVPIALELAKQGA +EGALDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLTLDRV-GK +EATEKTLRDLGFEHTTVSQDCGEVLRALQPEHSCATTAEEITRLLGLIWRDEAAAPAACA +DVRRWMDLQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Nocardioides luteus TaxID=1844 RepID=A0A1J4N689_9ACTN +----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD +RGLLSLDEPIAVHTDFDSAVAGARWEAIGSALPLADLVRRSLTVSGNLAVNLVLERV-GL +EEVAAVLADAGVTMTTVARGIEDAPA-REAGLQNLVTANDMGKLLTKLASGRLLSPESTA +ELEGILVAQEY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIRPAQGDPQVMVVLTTG +LDD--DESEFRISEVARYLWS-- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI000563D612 +--TTDEQLRAVFADAGCRGWVRAERIDGIGTAvDYEGDDPVVAASVWKIVLLVAAARAFD +EGSLTATDSVRLVPAQCSPPTGISSFADPVTMSWRDIARSMITVSDNAAADALLGAV-GL +DALTRVIDDLELEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSIWLGTAASTAQCL +YMKAVLAQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA +ARMDLPLVDQAIGHAARIAV--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SID8499 TaxID=2706106 RepID=A0A6B3E393_9ACTN +------------------------------EV-ALGADEPVVIASIFKVLLVLEFARQAV +AGQLDPRERVRVGAADRLGGWGTAGCLDDVELSLRDLAHFALSVSDNTAADLLLAHV-GL +DTVRLLAKELGLERTRIAGGPRALLEVLDPRRTTASTPREITRLLRLVWSDAAGPPDACA +LVRELMGRQVF-RHRLASGFPDGVTVAAKTGTLP-GLHMEAGVVRYPDGAHYAVAAFART +RDPASAAVDAALGRAARLAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Pseudonocardia sp. HH130630-07 TaxID=1690815 RepID=A0A1B1ZKC8_9PSEU +-----------------------------DEV-AVGADVPVVMASVYKLLVLVGYCRAVD +DGRLDPREPVVVGPGWRTPPTGVSALADPVTMSRRDLVRSMITVSDNAAADVVHAEV-GR +DRVAALPGELGLTGTRVRGGTAEVFAALSPAFGSSTTAADSTSLLARLWRGELASAAGTA +FAREVLSGQIW-PHRLRAGFPAAAAVAGKTGTVG-AVRNEVGVVTYPGEHPVAVAVFTHA +ARSDVPRADAAIGAAARVAVN-- +>[subseq from] Serine hydrolase n=1 Tax=Rhodohalobacter sp. SW132 TaxID=2293433 RepID=A0A371QK48_9BACT +----EDEIRERIDAFQGDAGLYVYHLDSGFEF-TIHPDTVFPTASTVKIPIMIGLFDKIE +RGEIEYTQVFQYSDEHADPGDDIINQLPEGTVELNRLIHLMMSTSNNTASLWNQYIAGTG +TEINNLMDQKGFSDTKVNSRTPGREQIWEEYGWGHSTPRELARLLLNIYKGEMISPGASE +KMYRIMGRNFW-DGEALSQIPPYVNVASKNGSVAR-SKSEVLLVNAPSGD-YLFALMTKN +QEEYDNEGFVLLREISAILYNHf +>[subseq from] Serine hydrolase n=1 Tax=Tsukamurella sputi TaxID=2591848 RepID=A0A5C5RMC1_9ACTN +---AAARIDAAFADAGCNGWVHARVIGHPAEL-SVGGAQPVVPASIYKVLLLVAAARAFD +TGRLDPRTRVTVDPGSATPPTGIAALSDPVEMSLRDLLRSMIAVSDNAAAGELMRRV-GL +DAVQETARDLGLHGTRIVGGDAEIHAAYDPSFGSATTAADMTALLAAIWTDTAASPAQCA +FARSALGGQVF-RHRVASGFGSAPSIAGKTGTLG-ALRSEVAVVAYPGEHPVAVAVFTHA +ARNDLPRVDAAIGTVAAIAVD-- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Candidatus Woykebacteria bacterium RIFCSPHIGHO2_02_FULL_43_16b TaxID=1802601 RepID=A0A1G1WQA8_9BACT +------------------------------------------------------------ +--------------------------------------YNMITVSDNEDAIYLSEMV-GW +NTIQKVMNRYGLAKTTLGSPP-------------MSTPMDIATYLELLHDKKLVNEAYSE +VMYRTLLEQKV-NDRIPRDLPKGTKVAHKTGELDD-VRHDVGIVETPNNT-YLIVLMSKN +ME-NEVRVKNIMADISKEVFDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora halophytica TaxID=47864 RepID=A0A1C5HC10_9ACTN +---VQQRIGQLFAQAGGSLHVVPVDGPHEQEV-ALDADRRTVIASVFKILLVLEFARQVA +AGQLDPTERVLVTAGDRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GA +DVLPMLAAELELGRTRLRGGPRHLVEVFDPERTSSSTARDLTRLLTLIWCDRAGPAVACA +TVRELMSRQLV-RTRLASGFPPGVRVVSKTGTLP-GLYLDAGVAEYPDGARYAMAVLVRA +EHARRIDVDLAMGEAARIAVQ-- +>[subseq from] Uncharacterized protein n=3 Tax=Candidatus Shapirobacteria TaxID=1752721 RepID=A0A2M7BCL8_9BACT +----KKSIESILLPLRGKYGIFYEDIGSKNSF-GINEKEVFTAASLIKMPVLITLYREAE +IGNINLDEVYKLQASDKREGAGALQNKPGFEISYRKIAELMGEQSDNTAFNVVANKL-GT +EKIQNTINALGMKNTSYA--------------ENLTSPVEMGLLFRKLYLEKIISDKNRD +EILSFITDTIW-EDRIPVGVPEGINVSHKIGTEV-GVISDAGIVFGP--KPFILVIMSQE +VNE--IEARKALPEITKKIYE-- +>[subseq from] Beta-lactamase n=1 Tax=Clostridium chromiireducens TaxID=225345 RepID=A0A1V4I9M5_9CLOT +------EIKRYLESRIGTYSFFFEDLESGFSY-GYNENVQMTSAGCMKLPIAVSVIKYIQ +DEKGSFLDRVKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIEIV-GI +DNINEDIIAQGLKNTKLNRKTSDE-RATSSGIENITSALDLARIWKHLYNSSYLNEKNST +MLIDILQRQQM-KNKLALYIPDDFEISSKTGDKSS-VENDTALIHTQKG-SFTFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium estertheticum TaxID=238834 RepID=UPI0013E92FB0 +-------IKKYLETREGTYSFYFEEINSGYLY-GLNENKEMVSAGCIKLPLAMVLLKEVE +DGKIDLQSKIKIEAEDKTHSNGIIHELSGKEYSLYDLLIAMLIQSDNTAANKIIEIL-SM +QRIDELFVGMGLKNTKLKRITTDAKLE-QDELENITSSFDLSKCFKLLYLKQYLNEENSN +LLLRILKKQQV-TNKLPFYVPKQIQIANKGGSLDT-VENDTSIIMIEKGN-FLFTVMANN +LP-NNVYGITTISRVGKMMWD-- +>[subseq from] Putative beta-lactamase n=1 Tax=Scytonema sp. HK-05 TaxID=1137095 RepID=A0A1Z4IZ77_9CYAN +---LQRKLEAVAKGSDGRVGICAEEIKSGAIA-CVNGDQRFSLQSVMKLVVGAAAMDAID +RGQMRLEDVITVRKNDLSLVQPIADLVAQRGTTVADLISRAIIESDSAATDLLFAQVGGA +EGIQTFLKTKKISGLRVDRDEKHLQTAYLKDERDTATPRGMVTFLSALARGK-------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Caulobacter sp. X TaxID=2048901 RepID=A0A2G5R121_9CAUL +--DLRKSIDPIAARAPGVLGVAAEDLGTRQLW-DFNGDHPFMLGAAARIPILAAVLADQA +AGRLDPNETITVRDVDLSPPSAVADAWPGRRYTVAAL-EALARAGDNTALDLLAKRIGGP +GAVNGWLGVRQLTGISVDRYRRQVETRRAADDRDTATPVGLVRLLEAFNTREAFASADPR +LLTG----D--DPGYLATGLPKGAKIWQAAGANRTPESHAVALIELEDGRRIALAVFLSG +STADTAAREAIIAETGRTVLKSf +>[subseq from] Beta-lactamase class A n=2 Tax=Bacillaceae TaxID=186817 RepID=A0A660BV67_BACCI +--KLSKLINKIVQEYEGHFGIAMEW--RGQGF-FLNENDVFPSASLIKLPVMVESFMQSS +GGTLALEDLVEVRSLLRTGGAGIVQYMSPQSLSIRDLLTLMMIVSDNMATNYLIERL-GM +DNVNRRCQQLGMSSTVLQRKMMDREA-RKRKIENYTSPHDILRCLKAIYNDRNQSGK--- +---TILYHQQL-LDKLPRGENSGIRIANKTGELDK-VEHDCAIIEHEDE-IIFIAILTDQ +LTAN-QKGKELIQLIGASIFE-- +>[subseq from] Cell wall-binding repeat protein n=1 Tax=Marvinbryantia formatexigens DSM 14469 TaxID=478749 RepID=C6LJ76_9FIRM +------------------------------------------------------------ +--------------------------------SVKNTISSMITVSDNTAFNTIVRTI-GT +SYINTWCKANGYTGTNQGHGLSPSSNLSNGTGSNVTTAADCGKLLESIYRGTCVSKSASK +KMLGYLKKQTR-RSKIPAGVPSGVTVANKTGETDD-TTHDAAIVYSKGA-DYILVVMGDT +PG-SGWASTANITKFSKIVYNYf +>[subseq from] serine hydrolase n=1 Tax=Oceanobacillus timonensis TaxID=1926285 RepID=UPI0009B9FEFD +--------------------------AGDEEI-AFHHKEEVRAASIIKLFILAAAYYEEE +KGNLDLSRQVCISSSDMAGGAGVIPYLSDKQYTYQQLLELMIIVSDNTATNVLIDYI-GL +DNIHVFIQTIGCKQTTLERKLMD-EEAIKHGLENKTTCYDVMHLLDFFTENDILSSYAQE +KMLTILGNQQL-NNKLTAYTSHTIRAFHKTGELNR-AEHDAAIFQTADK--LLKAVVLTE +GWTNNGHGQQFHQKTGLHIYH-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces hirsutus TaxID=35620 RepID=UPI0006E43337 +-----------------------------CEV-GIGADDPVVIASIFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLARV-GL +DTVRLLAAELGLQRTRIVGGPRDLLEVLDPRRTTASTPREITRLLRLIWTDAAGPPEACS +FVRDLMLRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGGCYAVAVFART +HA-LAASRPTVDAAAGRA----- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis thermalba TaxID=944492 RepID=UPI000E267D1A +------------------------------ES-GLGPDEPVVLASVVKVPLVLELARQVA +AGQLDPADRLRVGAADRLGGTGTAGCADDVELSLRDAAFFALSVSDNTAADLLFDRV-GL +DNVRSLLRELGLARTRVIGSPRDVVAALDPLRTSATTPRDMTTLLAAIAGDTAGPPEACR +WVRQLMGQQVN-WHRLTAAFPPQVRVWGKTGSLL-AVRNEISVAEYPDGARYAVAVFTRA +PTSRLPDVDHAVGAAARAAIE-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. BL1 TaxID=2478709 RepID=UPI000EF595EA +---VAERIGEIFGRAGVRGCLHVVDVDAGGDV-ALRADEQIVIASIFKIMLVLEFARQAA +AGQLDPTERVVVGPADRLGGWGVAGCADDVEISLRDLAYLAMSVSDNTAADLLLRRV-GA +DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEHTSSSTARELTRLLRLVWRDEAGPAPACA +MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRT +QRARRIDVDLAMGEAARTAV--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces prasinus TaxID=67345 RepID=UPI0006EB8F13 +---------------------------GGREV-GVGADDPVVIASIFKVLLVLEFARQTA +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLDRV-GL +DTVRLLAAELGLERTRIVGGPRDLLEVLDPRRTTASTPREITRLLRLIWTDAAGPPEACS +LVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRHPDGECHAVAVFART +HA-LAASRPTVDAAVGRAA---- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V7CEB8_9BACT +--DLAKRLNELCDAEKFQASWYLKDLGTGASA-DRRGAVPVPSASTRKISIMMAALAAVH +AGKLSLDQKVTIDARYQDNDSGTFQHLTPGFITLRDALVMMIIVSDNTCTGTVVDLV-GL +ANVQRYSESVGLTGTVHRYGIPKLAPDHSLDRVTTTTPNDQGLLLALILQGTQCTTALCR +LGLDILSLQKL-KTRLPSLLPLGTKVAHKTGTGHR-CYNDAGIIFKADRPLCVLTAYTVD +VPETFAAAYRLIGR--------- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora chokoriensis TaxID=356851 RepID=UPI0004C40E6F +--------------------------GGGREI-GVRADEQVVIASIFKVLLVLEFARQVE +AGQLDPTERVLVTAADRLGGWGLAGCTDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP +DLLPMLAVELGLTRTRLLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMAQQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA +VEPRRIDVDLAMGEAARTAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Ruminiclostridium sufflavum DSM 19573 TaxID=1121337 RepID=A0A318XIP7_9FIRM +-dELEKLISDYTSKLPGKYGVTFIDLATGETV-NINDKTEYIAASTSKLPINVLLYKKIE +AGEINPEDKLVYKQEDLEYTGSIIGTPFGTEYSVRETSKLSIQKSDNCGVNMLIRLL-DI +ENVRNYIDEVGGQVHY--------------GKTHRSCPYDMAQIAQDLYKLYLNNEEVYG +ELLSYMETTDW-HDRIDAKLPKEVKVAHKIGNQTT-TRNDVGIVFAT--HPYVLSVMNDN +VN--IDAATKAIAELSKKIYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Nocardioides sp. SLBN-169 TaxID=1571486 RepID=A0A542T5D7_9ACTN +----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD +RGLLSLDEPITVHPDSAVVGSRFEWAAVGSPLRLGDLVRRSLTVSGNLAVNLVLERV-GL +EEVATVLADAGVTMTTVSRGIEDAPA-REAGLQNLVTANDMGKLLTKLASGRLLSPESTA +ELEGTLVAQEY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIRPAQGEPQVMVVLTTG +LDD--DESEFRISEVARYLWS-- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora musae TaxID=1894970 RepID=A0A3A9XXJ1_9ACTN +-------------------------VAGGREV-AVGADEQVVIASIFKILLVLEFARQVT +AGQLDPTERVLVTGADRLGGWGLAGCDDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLARTRIVGGPRQLVEVFDPERTTSSTARDITGLLGLIWRDEAGPAAACA +MVRNWMARQLF-WTRLATGFPPGVRVAGKTGTLP-GLHMEAGVAEYPDGGRYAIAVFART +AQTRRIDVDLAMGEAARTAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Kitasatospora sp. MMS16-BH015 TaxID=2018025 RepID=A0A2H5B9J2_9ACTN +----TDDIREIFERAGCTGVLCVRSLQDDAEV-ALGADGPVVLASVSKVQIALEAETWFA +EGRLDPREPVRLTGADRTPGPVGTSLFSDEAVSWRDLVVLMLTISDNLATDALLGRF-GV +EAVNRTAARLGLSATVLDSDLRTMLDALDPERGTRSTPREMTELLRLIWTDRAGPAEACA +RVRTVMARQLT-RHRIASAFRPPVQVAAKSGSLFGVVRNEIGVVTHPDGGQYAAAVFTRA +RPSDEAAVNRAIGAVTALAV--- +>[subseq from] serine hydrolase n=1 Tax=unclassified Clostridiales (miscellaneous) TaxID=39779 RepID=UPI0009E982BC +--SLESRINAEIYNFSGMIGLYANDF-KGNII-EINSRDKFETASTIKVFILAELYKQIY +EKKISPNKILKYDKENYVIGSGILRDLDYSVMTAKSFAILMIIISDNIATNILIDLL-GI +DNINNTCQDLGFKDTILHNKID-FEK---HSKLGTTTPKDYGKFFELLYKKELWSKEISE +EMIGIFKNQHY-NTILTRDLPPYISIASKSGSMD-ACRNDGGIVYTPYGG-YVISIFTKE +FVDNDHESYRFGGKISRLMFDQ- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis rhizosphaerae TaxID=2053003 RepID=A0A558BBW7_9PSEU +-----------FVAAGVRGWVHARCLACDGEA-GLAPDEPVVLASVVKVPLVLEFARQVA +AGQLDPADRVRATAADRLGGTGSAGCLDDVEYSLRDAAFLALTVSDNTAADLLFERV-GV +DNVRSLLRELGLTATRITGPPRHIVQALDPLRTTASTARDMTALLALVARDLAGPPEACR +WLRELMGQQVN-WHRLAAAFPPEVGVWGKTGSLP-AIRNEIGVVEYPAGTCYAVAVFTRA +EVSRQPALDHVIGEAAREA---- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. Cs-700 TaxID=2589818 RepID=UPI0014091A0C +---VKEKILECFHGLEGNQSIYVST-PDG-EI-ALHSDQPISSASIIKIAILIEALRQVD +VEQLSIDQVVQIDNVNYVGGAGVINHLSRDHWKLADLLKLMIISSDNTATNQLIDLV-GE +HNINHTMKAAGAFHSKLMRRMMDRNA-LKSGLDNMVSGKDTYLLLREFVTQHLLSQSSME +WGVEVLLQQQF-KDKFPSKISKENLLAHKTGELI-GVEHDAGILFTSNG-PVVYAFLTAG +LL-ENRYGREAIANAGRLLYDFy +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. RB5 TaxID=2585196 RepID=UPI0012967F6C +--SAAEEIRRVFEAVGADGQVHAVPIGSTSEV-DLRAGEPAVIASLFKVPLVLEFARQCA +AGQLDPRERVRVTAEHRLGGWGTGGCADDVELSLRDLAFFALSITDNAAADLLLDRV-GL +DTVRLLAQELGLTSMRLTGGSREVLRALDPARTNSAAPRDITRLLRLVWRDEAGTAQACA +VVRDLMGHQVF-RHRLPTGFPADVRIAAKTGTLP-GLHIEAGVIQPPGPDAYVVAVFART +RRARLPEVDAAIGTAARLAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. San01 TaxID=2494256 RepID=A0A437PM02_9ACTN +---VIAKINDRAKQAGVRVRLHAAEIDGTRRI-GVDEHSPVVTASVFKVPIALELARQAA +EGGLDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILARV-GK +EKTEKSLRRLGFENTTVPQDCGEVLGALRPEHTCATTAEEITRLLALIWRDEAAAPTACA +DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] Serine hydrolase n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A2E5Q7A5_9PROT +---LENDLNQLCDEQPFHTGWYVRNLYTGDNL-QRHGXVVVPSASTRKIAXMMAALKAVS +EGGLALDQPVTMSAGYQDNDSGCFQHQPGFTIQLRDALVMMIIVSDNTCTGVVADLV-GL +ESINSXCQSIGMTGTVHRYGIPGMAGYLPAAQTNATTPADVAHLLDLILRGSGCRPESCQ +LAIDILSWQRL-RNRIPARLPLGTRVAHKTGTTAK-NYNDAGIVYFEDTPLFIISSYTDA +VEAE------------------- +>[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00142F88E7 +------------DRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE +AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL +PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCT +AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA +DPTDASPDDDACQLIADISARA- +>[subseq from] Uncharacterized protein n=1 Tax=Amycolatopsis japonica TaxID=208439 RepID=A0A075UVJ6_9PSEU +--QVTETITERAKEVGVRVRLHAAEIDGSRRI-GVDEHAPVVTASVFKVPIALELAKQGA +EGALDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILDRV-GK +EATEKTLRDLGFEHTTVSQDCGEVLGALQPEHSCATTAEEITRLLGLIWRDEAAAPAACA +DVRRWMDLQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] serine hydrolase n=1 Tax=Virgibacillus sp. YIM 98842 TaxID=2663533 RepID=UPI0013DC1933 +---LKKEVQRIEADTDGTIGVFI---DTGEGIiNMNEKEVMSSASVIKVPILAEAIRQAE +RGDLIWEDEVLVQESDAVGGSGVIRDMDLPVMTVRELAELMMTVSDNTATNMIAERV-GF +DQVNWTCIELGCEDTVMQNSIYTSMPQ-DRGPHNYTNAKDMATVVSGVINEDIFSSEGKE +EFLRIMREVPD--GRLTGYKDGDIQTGRKGGSTAPRVLHDVAVFTLGDKE-IYAAVLTHN +VVPN--TATPTISEIGKEIMDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Jiangella alkaliphila TaxID=419479 RepID=A0A1H2JP24_9ACTN +---------------------HAVDVGSGVEV-GVEPDAPVVTASVFKVSVLVELCRQFA +TGEREPADRLRVPAGARTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR +DRINALMVELGLPGTVLEEDCAGLFRVLDPRTTNRSTPRETTTLLRRIWAADGLPAAAGE +EIRRIMALQVW-PHRLTSGFQDDVKVSGKTGTLSH-VRNEVGVVEYPDGATFAVAVFLRL +PGGENPAADAVIGTAARIAVDH- +>[subseq from] serine hydrolase n=1 Tax=Aestuariivita boseongensis TaxID=1470562 RepID=UPI000A4713E1 +------------------------------------------------------------ +----------------------------------------------------------GP +AAVTEYLRRLRITDISVDRTTGEIIGDFEADPRDQSTPLAMLQLLLAIDNGTATSAESRD +FLIDVMSRTRTGAGRLKGLLPRGTPVANKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS +SETSEADRDRAIAEVARSLFDYf +>[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI000362CD43 +------------DRVSGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE +AGHLDQDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL +PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA +AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA +DPTDASPDDDACQLIADISARA- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ322 TaxID=2572904 RepID=A0A560AX35_9ACTN +--------------------------GGGREV-GVRADEQVVIASIFKILLVLEFARQVE +AGQLDPTERVLVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP +DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA +EQPRRIDVDLAMGEAARTAV--- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora inaquosa TaxID=2203716 RepID=A0A3N9WST4_9ACTN +---VEERIESIFAAVGVTASLHVVDLDGGREV-GVRADEQVVIASIFKILLVLEFARQVE +AGQLDPTERVLVTAADRLGGWGLAGCTDDAEVSLRDLAYFAISVTDNTAADLLLRRV-GP +DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMAQQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA +EEPRRIDVDLAMGEAARTAV--- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. ADI98-10 TaxID=1522763 RepID=A0A3N6IXM6_9ACTN +----------------------------GGEV-AVGADEPVVIASVFKVLLVLEFARQVA +AGQLDPRERVRVGAPDRLGGWGTAGCADDVELSLRDLAFFAMSVSDNSAADLLLARV-GL +DTVRLLAGELGLDRTRIVGGPRDVLDVLDPLRTNASTPREITRLLRLVWSDEAGPPEACS +QVRELMGRQVF-RHRLVSGFPDEVAVAAKTGTLP-GLHMEAGVVRYPDGGHYAVAVFART +REASRTAVDAALGATARIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces alni TaxID=380248 RepID=A0A1I2H1Y1_9ACTN +-------------------------------I-GYEPDQLVCTASVHKVCVLLTAHRLAA +EGRLRLTERIDCRAAGRTVGSTGLSAMLDDVMSARDLAYLMMAVSDNAAADLLLERV-GL +DEVNRTTRLLGLERTLAVENFAAAQAALDPARSNRSTPRELTRLLGALWHDELCSPEHGE +AMRRLMSLQVW-PHRLASGFPDDVGLAGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA +ADHVLPAADSVIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Aminicella lysinilytica TaxID=433323 RepID=UPI00105BD603 +-----------IKKIPGRSGLYYKNLVTNEVL-AYNETEEFHPASMIKLPVFMAISKMVA +EGKARWNDKIKITYDVRVPSCGAFNAFTDEPVDVKTLCNLMITISDNTAANVLISHF-GI +DRLNGEFAATGLEKTHLERLFYDDEMQ-AKGFNNKAVPAELGGLLEKLHRKTFVNEKVSD +EVLAVLYDQQD-KCYIPEWFEDECPVANKTGGAR-GILGDEALVQTD--KPFVLVMMFNE +TV--TPEAAEFMRHAGKQLY--- +>[subseq from] serine hydrolase n=1 Tax=Silvibacterium bohemicum TaxID=1577686 RepID=UPI000678C4D4 +-qALQAKLSVLAAGHHGKVALYAEDLVTGKTV-ALNADTPVQTASVIKLTVLYEALEQVR +DGKVHFDDKLTLTHGDQVAGSGVLAFFDTPQLTFKDALTLMIILSDNTATNLAIDHL-GL +KSIDDQIVALGLKDTWLYKKIYLPSSDQKTFGLGKTTAYEMATVMKRLVTCDL------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / BCRC 12538 / CBS 129.76 / JCM 10878 / NBRC 16125 / NRRL B-16091 / INA 9442) TaxID=644283 RepID=D9TD39_MICAI +----AERIGEIFGPAGVRGCLHVVDVDAGGEV-ALRADEQIVIASVFKIMVVLEFARQAA +AGQLDPTERVLVGAADRLGGWGVAGCADDVEVSLRDLAYLAMSVSDNTAADLLLRRI-GA +DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEHTSSSTARELTRLLRLVWRDEAGPAPACA +MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRT +ERARRIDVDLAMGEAARTAVD-- +>[subseq from] Uncharacterized protein n=2 Tax=Bacillus circulans TaxID=1397 RepID=A0A0J1I965_BACCI +--KLSKLINKIVQEYEGHFGIAMEW--RGQGF-FLNENDVFPSASLIKLPVMVESFMQSS +GGTLALEDLVEVRSLLRTGGAGIVQYMSPQSLSIRDLLTLMMIVSDNMATNYLIERL-GM +DNVNRRCQQLGMSSTVLQRKMMDREA-RKRKIENYTSPHDILRCLKAIYNDRN------Q +SGKTILYHQQL-LDKLPYYCGSGIRIANKTGELDK-VEHDCAIIEHEDE-IIFIAILTDQ +LTAN-QKGKELIQLIGASIFE-- +>[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00037AFF2F +------------DRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE +AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL +PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCT +AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA +DPTDASPDDDACQLIADISARA- +>[subseq from] Beta-lactamase class A n=1 Tax=Nocardioides sp. YR527 TaxID=1881028 RepID=A0A1G9HDR3_9ACTN +----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD +RGLLSLDEPIGVHPDSAVDGSRFEWAAVGSPLPLGDLVRRSLTVSGNLAVNLVLERV-GL +EEVAAVLADAGVTMTTVLRGIEDAPA-REAGLQNLATANDMGKLLTKLASGRLLSPESTA +ELEGILVAQEY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIRPAQGEPQVMVVLTTG +LDD--DESEFRISEVARYLWS-- +>[subseq from] serine hydrolase n=1 Tax=Oceanobacillus sojae TaxID=582851 RepID=UPI0009887920 +----------------------------EHRI-AFNEMKQLRAASIIKLFILAAAYYEEE +RGNVNLSKQVNIPGLDLAGGSGIVSYLSDKQYTYQQLLELMIIVSDNTATNALIDFI-GL +DSIQTFIEKIHCENTKLERKLMD-EEAIKLGLENVTTCYDVMLLLDLFTENNILPEHRRQ +QILTVLENQQF-NSKLTASYDSDIRTFHKTGELT-GAEHDAAIFQTDDK--LLKAVMLTE +GWTNNGEGQQFHQAAGAHIYHY- +>[subseq from] Beta-lactamase n=2 Tax=Mycobacteriaceae TaxID=1762 RepID=A0A0E3XSW7_MYCCH +------QIRAVFLDAGCRGTLRAERVGTLTPVvDVDGDRPAVSASVYKIFVLIAAARAFD +SRTLDPDATVRVVPADCTPGPTGISTFSNPVLSWLDLARLMITHSDNTAADVLLAAV-GL +DTVNEITEELGLGSTRIIGGTSALQQAFDPAYTTSTSAVDTARALSAIWTGAAASPQSSE +MMRHILAQQIW-QHRIRSAFPRDVIVAGKTGTIGP-IRNEVAVIVFPGEPPMTVSVFTRA +ARADLPNVDRAIGEAARIAIT-- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V7DMA2_9BACT +----VADLDKLCDELPFQTGWYLKDLRRGETA-RRNGDVVVPSASTRKIAIMMTALKAVH +DGKLALDQPVTIQVKYQNNDSGCFQYQPGFTIQLRDALVMMIIVSDNTCTGMVVDLV-GL +DAINALSHAAGMRGTTHRYGIPGMAGYRPASETNATTPTDVGLLLEHILRGSGCTPVLCQ +LGLDILSWQRL-RNRLPARLPLGTKVAHKTGTTAR-NYNDAGIIYQGNQPLFILSAYTDD +VPPEHTAAHTLIARMSRLCYD-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=A0A328NK15_9ACTN +--------------------------GGGREV-GVRADEQVVIASIFKILLVLEFARQVE +AGQLDPTERVVVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP +DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA +EQPRRIDVDLAMGEAARTAV--- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces lividans TK24 TaxID=457428 RepID=A0A076MHI3_STRLI +-----------------------------DEV-AVGADEPVVIASIFKVLLVLEFARQVA +AGQLDPRARVRVTAGDRLGGWGTAGCADDVELSLRDLALFAISVSDNSAADLLLAQV-GL +DTVRLLVKELRLERTRIVGGPRDVLQVLDPSRTNASTPREITRLLRLIWCDEAGPPQACA +WVRELMSRQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART +RESSRTAVDAAIGTAARIAVD-- +>[subseq from] Serine hydrolase n=2 Tax=Couchioplanes caeruleus TaxID=56438 RepID=A0A1K0GDH9_9ACTN +--------------------LHARDIDTGRAM-GCRAGEPVVLSSVFKILLALEFARQVA +SGALDPAERVTVGGGDRLGGWGTGGCADDIELSLRDLAYFTMSVSDNTAADVLLRRV-GP +DLLPLLAAELGLTRTRVVGGPREMLEVFDPQRTTSSTPEEITRLLQLVWRDAAGTPEACA +MVRDLMARQMF-WTRLAAAFPAGVRVSGKTGTLP-GLHMEAGVAEYPDGGRYALAVFVRT +HRTSRMDVDRLLGRAAAAAVRH- +>[subseq from] Beta-lactamase class A n=1 Tax=Gordonia sp. v-85 TaxID=1761786 RepID=A0A1C4BQM1_9ACTN +----DRTVHETFADAGCSGCVHVRTIGTPVEY-CHDADTPVVLASVYKLAVLVSLCRMAD +RGDIDLTASITVDPTRRAHGPTGLALFSDPVISWRDLATSMMTVSDNVAADVILAHI-GL +PQIHDDLVDLGLTHTRIIGGIAESHAAYDAAYSSAATPRDCTTLLDAIWTDRAASATSCE +FIRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AIRNEIGVIEFPGEVPIAVAVFTMS +ARSELPEVDRAIGEVARVIVT-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535JCH0_9CHLR +--DLVRQLDGLIASFPGGAGIWIGDPTVATPIfTHDPEEHVITASLYKLGVLAEAERRVD +TGELRYDDIVTIESDDITVDGSF--EDAGTQLTLDEALEAMITISDNGSALALWRIL-GG +ENIDATLEKAGVKDFHVAFDESE---------DNWATPHAIGTFFTLLAKRQLISAAASG +RMLERLERQQI-NDRLPAQLPADTVIAHKTGNLG-GLAHDAGIIYTKTGPRVVVAMTWNG +LDED---AANFISSIGSLVYS-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora pisi TaxID=589240 RepID=UPI000EB32A00 +-----ERINRIFTVVGVDAQLHVTDIDSGAEV-AIRADEQVVLASVFKILLVLEFARQTA +AGQLDPTERVVVRAEDRLGGWGTAGCADDIELSLRDLAYFAMSVTDNSAADLLLRRI-GP +DLLPLLAAELGLTRTRIVGGPRQLLEVLDPERTTSSTPREITRLLGLIWREEAGPPPTGA +LVRDLMARQVF-WTRIASGFPPPVRVSAKTGTLP-GLHMEAGVAEYPDGGRYAIAIFARM +RQLDTRRVDLAMGEAARTAV--- +>[subseq from] serine hydrolase n=1 Tax=Tsukamurella pulmonis TaxID=47312 RepID=UPI000798021E +-------IDGVFADAGCNGWLHARVIGHPAAL-SVGGEQPVVPASVYKVVLLVAAARAID +AGRLDPRARVTVDPASATPPTGIAALTDPVEMSVRDLLRSMIAVSDNAAAGELMRLV-GL +EAVQESARTLGLSGTRIVGGDAEIHAAYDPSFGSATTAEDMTALLAAIWTDTAASPAQCA +FARSALGGQVF-RHRVASGFGSAPSIAGKTGTLG-ALRNEVSVVTYPGEHPVAVAVFTHA +ARNDLPRVDAAIGTVAAIAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora pisi TaxID=589240 RepID=A0A495JV13_9ACTN +-----ERINRIFTVVGVDAQLHVTDIDSGAEV-AIRADEQVVLASVFKILLVLEFARQTA +AGQLDPTERVVVRAEDRLGGWGTAGCADDIELSLRDLAYFAMSVTDNSAADLLLRRI-GP +DLLPLLAAELGLTRTRIVGGPRQLLEVLDPERTTSSTPREITRLLGLIWREEAGPPPTGA +LVRDLMARQVF-WTRIASGFPPPVRVSAKTGTLP-GLHMEAGVAEYPDGGRYAIAIFARM +RQLDTRRVDLAMGEAARTAV--- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora tulbaghiae TaxID=479978 RepID=A0A386WQ40_9ACTN +-----ERVAEIFGRAGLRGCLHVVDVDAGGDV-ALRADEQIVIASIFKIMLVLEFARQAA +AGQLDPTERVVVGPADRLGGWGVAGCADDVEISLRDLAYLAMSVSDNTAADLLLRRV-GA +DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEHTSSSTARELTRLLRLVWRDEAGPAPACA +MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRT +QRARRIDVDLAMGEAARTAV--- +>[subseq from] Beta-lactamase n=1 Tax=Flavobacterium sp. Leaf82 TaxID=1736238 RepID=A0A0Q4SJI7_9FLAO +-dKMKTEILEIIKDKKFDIGISVRNSKGVEIF-GHKSNEKYKMYSVSKFFLALKVLHLVD +KKTLLLNQNVSFAKSDLKAFSPLRDSNPEGIITLEKALYYIVNQSDNNVFDKLVDLSGGI +ESLNSYISSFTKNKN--SFFMSALYRDKEGTINNVVTPGFSSLLLYKLMKNKIISIESKN +ILLPLLETSIN-NKRIQALVPKNLKSFHKGGTSDRVASNDIGIVYLNEKDFFTIAVFISN +SLEDDAVNDAVTAKITEIT---- +>[subseq from] serine hydrolase n=1 Tax=Clostridium polynesiense TaxID=1325933 RepID=UPI0006932932 +--EMENNIKNYMGADLNSLGFIYYDTSTGEKI-SINENKIFLAASTVKVQLNMIAYDWAE +KGRLSLDDSIKYKESDNEDGTGILQNQDKSQFKIQELLDYSIIYSDNIATNMLFRTLGGY +KKVRSMVNK----KFGI-------NMDTS---GNYITPQGEFTILKYLYDNRT--NSNYA +HLIDVMKGTVF-HDRIDKYIPQDI-SAHKTGEYDY-YVNDVGIIFTEN--PYILVVYTYN +IE----NAHEKIAEISKMIYNY- +>[subseq from] Uncharacterized protein n=2 Tax=Kocuria polaris TaxID=136273 RepID=A0A0W8INN5_9MICC +----AQRLAELAEEVPGELGVVLLDPEGGEVA-ARNADRPFTSASLYKLFLAHAVLDEVD +RGTLSLSDTL-----------------PELGLTVEQALDVMISWSDNASGAALGRRL-GW +QEVEAFAHEQGFGATTFDPGTGSE-----DVVAMTTTPADVADLLDRLRRGELLSGPSTE +LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLQD-VSHDAGILELGGR-DYVVAVLTDG +WS-DYEESAPWFGEAGR------ +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. RP3T TaxID=2135446 RepID=A0A2T3VFA2_9ACTN +-----QRVGEIFGRAGLSGCLHVADVDDSREV-ALHADEQIVIASVFKILLVLEFARQVA +AGQLDPTERVLVGAADRLGGWGVAGCADDVEMSLRDLAYLAMSVSDNAAAELLLRRV-GP +DVPSMLAAELDLPRTRIVGGPRQLVEVFDPEHTSSSTARELTRLLRLVWRDEAGPAAACA +TVRELMGRQLF-WTRLTAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGARYAIAVLVRT +DQTRRIDVDLAMGEAARAAVE-- +>[subseq from] Uncharacterized protein n=2 Tax=Fusobacterium varium TaxID=856 RepID=A0A250LTC3_FUSVA +-eKFENKLLKILKKYDKKYGIIIKNLGNDFFI-KVGNMEQYQAASLIKLTILYELFNNPK +---YNLDEEMKITSTDKVAGYGIVQYHENIKFTLRDLAILMIILSDNTATNMLIDIC-GM +DSINFTIKKLGLKNTILQRKMMDSKSK-NIGLDNYTSPNDMMKLLEVLNEN--------E +EIISIMKKQLC-NNKIPYFFEEKIDFAHKTGDLPQ-IEHDIGILSIGDQK-IIIVIMTKN +FKN--KDEIELNNKVGELIY--- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536KL65_9CHLR +-dQLSADLQAIARTSGGRVGISLQELSGPRNL-SVNGGLNFVAASTYKLPLLMAEAQQIA +SGQVHRSDILCYAPSDAEDGW-FMDYQAGSCFTRDELALRTGRYSDNTAAHILVRYLGGP +DALNRYAKTIGMNNSAL--WVP-----------NTTTPDDLSQAMVSEALGRLGGAAAQA +WLYPILTRTTT-EQGIPAGLPGGTTVVHKTGTLD-ATENDAAYVRNG-RIAYVLSVTVDG +LD--VGAARSVIARISARIWQY- +>[subseq from] Uncharacterized protein n=5 Tax=Candidatus Beckwithbacteria TaxID=1752726 RepID=A0A2H0E2C1_9BACT +------TLENLIAGQPGDFGILVKSVNGQEEI-KLGENLVMTAASVIKLPVLIVYYQAVD +SGQLDPEAEYVLAEADRWKGTGSLQYQPAGTYTYRQVAQLAANQSDNMGAEVLIKKLGGY +AKTQQLVNKLGLTKINLKENE--------------ITAAEAGGLLLQLAQGKLLTPASRE +ELFRNLTKTVN-EDRLPAGVPDSVRVVHKFGSEA-GVVNDCGIVEA--GNPYVICVLTTA +VN--VGEVEPLLPQISAAVWD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora echinospora TaxID=1877 RepID=A0A562DCP6_MICEC +--------DARLAGVPGTVSVYAGRLDAAPTW-THAEHAPHYAASTMKVAVLAALYRAAE +AGALDPDTPVPVHNDFPSADGPRFWDRLDRTATLRWLAERMIVRSSNLATNILLGHV-GL +PAVAEVWALAGARHSVTGRGIEDYTAR-AAGITNLVTAADLAALLGALATGAIATPANCA +TMLDVLRAQEF-REDLPAGLPAGVPIAHKNGWVT-GVRHGVGVVLPHDAPPYVLAVCTTT +DL-TDPDACRLLADVSARVWA-- +>[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00040D8E2D +------------DRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE +AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL +PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA +AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDVPPYVIAVCTTA +DPTDASPDDDACQLIADISARA- +>[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora halotolerans TaxID=1981512 RepID=UPI0013D35726 +---LQGILRDLAASSGGTWSFTVRE--DGRTVaTVDGDLEVRAASTIKVPLLILALQDVA +AGRRALDEMLPVPA-ERVGGAGVLKLMPSVRLPLVEALELMIGVSDNNAANMVIDML-GV +DEAAGRITALGATGTRLERRLYDVEA-MRAGRDNVTTADDQALFLDLL------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Chloroflexi bacterium 13_1_20CM_2_70_9 TaxID=1805058 RepID=A0A1Q8ADJ1_9CHLR +--ELVQQIDGLVRTFPGGSGIWIGDPLSPSPLyTRNADTEVIAASLYKLGILAEAERRVD +AGELHYNDAVVIQDEDITEDGSF--EDAGTELTLDEALEAMITISDNGTALALWHIL-GG +ANIDQTLAKAGMPDFHI---------ALDDSEDHTATPRALGTFLTLLARHQLVSPAASD +RMLARLGRQKI-NNRLPAQLPENVLVAHKTGNLA-GLVHDAGIIYTKSG-PRVVVTMTWD +APV--DDADAFISSIGAIVYS-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium RIFCSPLOWO2_01_FULL_39_10 TaxID=1798622 RepID=A0A1F6KL03_9BACT +---------DSTKDKTGFYSIYYKDLKTGGAF-GIDEKQIQTATSVNKIPIIASLYYLAE +APNLSLDEKVTITDTDVQDTGSIRYQKMPQVYSLRNLAKLALKDSDNTAAHVLSVRI-GQ +DVIQRLVDDWGLAQTDMV--------------NNQTTAYDMGKLFEMIYKGKITNEANTN +ELLEFMTDTDF-EDRLSKNLPENVKVYHKTGDGE-GSIHDVGIIDTGNN-VYFLGVMTSD +VGEAEQETKDTIAEISEKIYK-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ285 TaxID=2035250 RepID=A0A4Y9VN56_9ACTN +---VAERVGEIFGRAGVRGCLHVVDVDAGGEV-ALRADEQIVIASIFKIMVVLEFARQAA +AGQLDPTERVLVGAADRLGGWGVAGCADDVEVSLRDLAYLAMSVSDNTAADLLLRRI-GA +DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEHTSSSTARELTRLLRLVWRDEAGPAPACA +MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRT +ERARRIDVDLAMGEAARTAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 04182 TaxID=2203198 RepID=A0A429FFY1_9PSEU +--EVSATITERAKEAGVRVRLHAAEIDGTRRF-GVDEHAPVVTASVFKVPIALELAKQGA +EGGLDLGERITVPPGHPTPPYGLATFRHEISMSWYDLAILMIGISDNVATDLILDRV-GK +ESTEKTLRGLGFEHTTVSQDCGEVLGALQPEHSCATTAEEITRLLGMIWRDEAASPTACA +DVRRWMELQVW-PHRLRSGFPDGILVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGVFTDA +IDSRVPERDALIGFAAAQAV--- +>[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00036949AD +------------DRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE +AGHLDPDGAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL +PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA +AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA +DPTDASPDDDACQLIADISARA- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535XF63_9CHLR +-qDLVRQLDGLVSAFNGGVGLWISDPSLPTPLfTHGPDEHVVTASLYKLGVLAEAERRVE +AGELHYTDSVVIEPEDITTDGSF--EDAGTTLTLDDALEAMITISDNGTALALWHIL-GG +SNIDTTLTKLGM---------PDFHVAFDDSEDNWATPHALGTFFTLLAKRQLISPAASD +RMLARLERQQI-NNRLPAQLPQGVVVAHKTGNLA-GLTHDAGIIYTKSGPRIVVAMTWDA +GDDDA------------------ +>[subseq from] Serine hydrolase n=1 Tax=Weissella sp. 26KH-42 TaxID=2506420 RepID=A0A4P6YTH3_9LACT +--------------------------------------QNQIAASTIKIFIALACMDAAN +TKAMNLDKQHSLQQAEQVGGSGILMDKPGTRFTIRQLIELMLTESDNTATNILIDELGGF +TVLDKYLNTWGYRNTQIQRKLMDLSN-WNNGKSNRISADDACDVLVKLYQQKIVTTAQRD +WLLSLMLRTTN-RTKLPSKLPADVICYNKSGESTKGVENDLAIIQRGSQ-VFAVVGLSQY +YDPNQPASHQL------------ +>[subseq from] serine hydrolase n=1 Tax=Oceanobacillus kimchii TaxID=746691 RepID=UPI000378C3C5 +------------------VSVIL-KTNTGIIC--SKETKQMQSASIIKLFILASAYHFKE +IGKLSLTEKIRISTNGHVKGSGVISYLTDVPLTYQQLLELMIIVSDNTASNYLIDRL-GI +SNIQAFIESLGCQQTRLERKFMDVEAQ-KLGKENVTSALDVLRLFDIFTENNFLGENSQQ +HILHILNNQQF-NSKLTAFTEPLVTSYHKTGELK-GVEHDAAIFLQNNK--FLKVVVLTE +GWENNGDGQAFIASFGKVL---- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DBFB686 +--------------------------GGGREV-GVRADEQVVIASIFKILLVLEFARQVE +AGQLDPTERILVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP +DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA +EQPRRIDVDLAMGEAARTAV--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. Root369 TaxID=1736523 RepID=A0A0Q6Y011_9ACTN +------QLHAIALRSRTTVAADAGAEQGAREV-AVGADDPVVIASIFKVLMVLEFARQVV +AGQLDPRERVRVAAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLARV-GL +DTVRLLAEELGLDRTRIVGGPRDLLEVLDPRHTTASTSREITRLLHLIWSDAAGPPEACA +FVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVARYPDGECYAIAVFART +QDASRATVDAAIGQAAGIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Actinospica robiniae TaxID=304901 RepID=UPI0007C4F339 +----------IEAGYQGTLSVAEID--GAGRV-DVRAGEEAYAASTFKIAVGLELACQGA +AGELELTESMRLSPDDCTPGQGLCLFEYPVEISLRDLAVLMLTISDNTATDAVIRRL-GP +ERVGARLAALGLKQTDFTCTIHEHFDALPH-LVPYTTAGDMARLTGMIWRDEAGPAAACA +QVRVMMGKQWL-TRKIATGFGAGTSVAAKSGTAP-AISNDVGVVTYPDGQRYAVAAFTRA +LDTDPDAAARAIGAAARLAVEH- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Brevibacillus sp. BC25 TaxID=1144308 RepID=J2GJ80_9BACL +-------------------------------------DELFIAESVIKVPIMAAVFTASE +LGHFRLDDQLVLRQEDLVGGSGILYGLSPGLLMIRDLVTLMIIQSDNTATNMLIDLV-GK +AQIDQTMIDLGMRQSCYSRKLMIYPLD--ITENNKITAGDVASMLGQLATGSYLSERACK +EMIAIMKKQQV-RNGLPSQLPNEWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKE +VT--AQSALNTLGLLGRAVYDY- +>[subseq from] serine hydrolase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI0009B8FD11 +--TTDEQLRAVFADAGCRGWVRAERIDGIGTAvDYEGDDPVVAASVWKIVLLVAAARAFD +EGSLTATDSVRLVPAQCSPPTGISSFADPVTMSWRDIARSMITVSDNAAADALLGAV-GL +DALTRVIDDLELEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSIWLGTAASTAQCL +YMKAVLAQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA +ARMDLPLVDQAIGHAARIAV--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces rubrogriseus TaxID=194673 RepID=UPI0013DB09D0 +----------------------------ADEV-AVGADEPVVIASIFKVLLVLEFARQVA +AGQLDPRARVRVTAGDRLGGWGTAGCADDVELSLRDLALFAISVSDNSAADLLLAQV-GL +DTVRLLVKELRLERTRILGGPRDVLHVLDPSRTNASTPREITRLLRLIWCDEAGPPQACA +WVRELMSRQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART +RESSRTAVDAAIGTAARIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A317GUG3_9CHLR +---------------------------ADRQI-VLYPDLVFPAASLAKLCIAVELFRRVD +LGQFDLSERFDTADEPRVGGGGMLDYLDPTTLTLHELCFLMIAASDNTAANFLLDLV-GM +GEVNETMRRLNLAGTRLERHFMDFSLR-ARGHDNVTCAKDIAGLLAMAHGNSF---PGAR +NFRELLAGQQV-ADDLRAWLPESAELGHKTGALDAGTFHDAGLLRGPAGS--CVFCLLTD +AQPDLPAARSAVGRVLRVLWESw +>[subseq from] serine hydrolase n=1 Tax=Streptomyces rubrogriseus TaxID=194673 RepID=UPI000D599C62 +----------------------------ADEV-AVGADEPVVIASIFKVLLVLEFARQVA +AGQLDPRARVRVTAGDRLGGWGTAGCADDVELSLRDLALFAISVSDNSAADLLLAQI-GL +DTVRLLVKELRLERTRILGGPRDVLHVLDPSRTNASTPREITRLLRLIWCDEAGPPQACA +WVRELMSRQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART +RESSRTAVDAAIGTAARIAVD-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Caulobacteraceae bacterium TaxID=1978230 RepID=A0A4Q3S151_9CAUL +---LDKGITQLADRIDGRLEVAVQNLDGGEIW-ARNAEQTFPLQSVFKAPLGAAVLSEVD +ARRLSLDEQITIEDMELSPLSPISQAWPGRKYTVRELLVAAVRDSDNTAADVLMRKIGGP +GALKSWLVEKGIIGLRIDRYERELQV---------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. CL-2 TaxID=1499684 RepID=UPI0005097B17 +-----KEIKRYLESRIGTYGFFFEDLKSGFVY-GYNENVSMTAAGCMKLPIAVSLIKAVE +DGKVDFLDKVKIKSEDKVYGTGIIHEFNEREYTVFELLVIMLIQSDNTAANKIIDIL-GM +EKINQDILEMGLKNTKLNRKTTDERD-NHTDVENLTSAYDLNLIWKHLYNGTFLNKDNGQ +MLIDILRRQQI-KNKLALYLCDDYEISSKTGDKY-GVENDTEFIQVPKGD-FSFTVLSSG +LPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces coelicolor TaxID=1902 RepID=A0A4R8MLL9_STRCH +-----------------------------DEV-AVGADEPVVIASIFKVLLVLEFARQVA +AGQLDPRARVRVTAGDRLGGWGTAGCADDVELSLRDLALFAISVSDNSAADLLLAQV-GL +DTVRLLVEELRLERTRIVGGPRDVLQVLDPSRTNASTPREITRLLRLIWCDEAGPPQACA +WVRELMSRQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART +RESSRTAVDAAIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00036A8FBC +------------DRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE +AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL +PAVADAWARGGARHSLTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA +AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA +DPTDASPDDDACQLIADVSARA- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=A0A1C4U1C4_9ACTN +--------------------------GGGREV-GVRADEQVVIASIFKILLVLEFARQVE +AGQLDPTERVLVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP +DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA +EQPRRIDVDLAMGEAARTAV--- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Chloroflexi (miscellaneous) TaxID=189774 RepID=A0A1Q7QI46_9CHLR +--ELVQQIDGLVRTFPGGSGIWIGDPLSPSPLyTRNADTEVIAASLYKLGILAEAERRVD +AGELHYNDTVVIQDEDITEDGSF--EDAGTELTLDEALEAMITISDNGTALALWHIL-GG +ANIDQTLAKAGMPDFHI---------ALDDSEDHTATPRALGTFLTLLARHQLVSPAASD +RMLARLGRQKI-NNRLPAQLPENVLVAHKTGNLA-GLVHDAGIIYTKSG-PRVVVTMTWD +APV--DDADAFISSIGAIVYS-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora zamorensis TaxID=709883 RepID=A0A1C5GR78_9ACTN +------------------------------EI-GVRADDQVVIASIFKVLLVLEFARQVE +AGQLDPTERVLVTADDRLGGWGLAGCTDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP +DLLPMLAAELGLSRTRVLGGPRDLVEVFDPEHTTSSTAREITRLLTLIWRDEAGSPAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA +DRSRRIDVDLAMGEAARTAV--- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536PM01_9CHLR +--ELVQQIDGLVRTFPGGSGIWIGDPLSPSPLyTRNADTEVIAASLYKLGILAEAERRVD +AGELHYNDTVVIQDEDITEDGSF--EDAGTELTLDEALEAMITISDNGTALALWHIL-GG +ANIDQTLAKAGMPDFHI---------ALDDSEDHTATPRALGTFLTLLARHQLVSPAASD +RMLARLGRQKI-NNRLPAQLPENVLVAHKTGNLA-GLVHDAGIIYTKSG-PRVVVTMTWD +APV--DDADAFISSIGAIVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536P6Q6_9CHLR +--ELVQQIDGLVRTFPGGSGIWIGDPLSPSPLyTRNADTEVIAASLYKLGILAEAERRVD +AGELHYNDTVVIQDEDITEDGSF--EDAGTELTLDEALEAMITISDNGTALALWHIL-GG +ANIDQTLAKAGMPDFHI---------ALDDSEDHTATPRALGTFLTLLARHQLVSPAASD +RMLARLGRQKI-NNRLPAQLPENVLVAHKTGNLA-GLVHDAGIIYTKSG-PRVVVTMTWD +APV--DDADAFISSIGAIVYS-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536CZF2_9CHLR +--ELVQQIDGLVRTFPGGSGIWIGDPLSPSPLyTRNADTEVIAASLYKLGILAEAERRVD +AGELHYNDTVVIQDEDITEDGSF--EDAGTELTLDEALEAMITISDNGTALALWHIL-GG +ANIDQTLAKAGMPDFHI---------ALDDSEDHTATPRALGTFLTLLARHQLVSPAASD +RMLARLGRQKI-NNRLPAQLPENVLVAHKTGNLA-GLVHDAGIIYTKSG-PRVVVTMTWD +APV--DDADAFISSIGAIVYS-- +>[subseq from] Serine/threonine-protein kinase PknB n=2 Tax=Desulfosporosinus acididurans TaxID=476652 RepID=A0A0J1FKZ2_9FIRM +------------QDSKGSYFMYLRDNTTKEEYaNSEANDSKVAGGLVYIPIMTTVLIEHF +NGNLNLDKPITVQG--IAGTGKLTRQDSGRSLSVKQLLELMMRYSDNTAANLLIDELGGL +ERINNTMRSLNIDGIVLNRKLMDQQ-AMNRGLENYCSPRGIGSLLSLLAENRIMAAQDCE +YSISIMGNNDH--TGMAKYLPDNILISHQTGILT-GVFNDAGIINTPKGR-VVLVLM--G +EKVDQDTAAEIFGKVARAVVEQ- +>[subseq from] Serine hydrolase n=1 Tax=Arundinibacter roseus TaxID=2070510 RepID=A0A4R4KF94_9BACT +-rELTRKIEQAIAGFGGDVGVYVHHIKKNRVV-EIQADTVFPTASMVKIPILCGLFDKLH +SGQLAYDSVLIYRDSLRYDDGIVGSLRDSAKIPLSYVLMLMETISDNTGSLWMQALAGGG +ATINNWLQKQGFVHTRVNSRTPGRADAQRTYGWGQTTPREMAELMTLIRFGGAISPDVSE +RMYRLLGRQFW-DGQALSQLPPEIKVAAKNGAVNR-AKSEVVYVHAPHGD-YVFCITTKN +QKKADNEGYVLLRTLSAILWNHf +>[subseq from] Uncharacterized protein n=1 Tax=Kocuria sp. UCD-OTCP TaxID=1292021 RepID=A0A0M2CWM0_9MICC +------------------------------------------------------------ +---------------------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW +EQVEAFAHEQGFTDTTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSTA +LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG +WS-DYEESAPWFGDAGR------ +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora avicenniae TaxID=1198245 RepID=A0A1N6SAM0_9ACTN +------KLDAHLDTVPGTVSAYVGRLDAEPVW-TRRADVTHYAASTMKLAVLVALHRAAE +AGALDLDAPVPVANASAQPGAPRFWARVGGTASLRWLAQRMIVRSSNLATNLVIGHV-GL +PAVAEVWTLAGARHSVTGRGIEDFAA-RDNGITNLVTAADLAALLGLLATGALASPAACA +QMLEVLVAQEH-REDLAAGLPPGTRIAHKSGWVN-GVRHGAGVVFPDDAAPYAVVVCTTR +DAGDDADACALIADVSARVWS-- +>[subseq from] serine hydrolase n=1 Tax=Nocardioides sp. YR527 TaxID=1881028 RepID=UPI000B870E0B +----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD +RGLLSLDEPIGVHPDSAVDGSRFEWAAVGSPLPLGDLVRRSLTVSGNLAVNLVLERV-GL +EEVAAVLADAGVTMTTVLRGIEDAPA-REAGLQNLATANDMGKLLTKLASGRLLSPESTA +ELEGILVAQEY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIRPAQGEPQVMVVLTTG +LDD--DESEFRISEVARYLWS-- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora arida TaxID=2203715 RepID=A0A3N9X6Q4_9ACTN +--------------------------AGGREV-GVRADEQVVIASIFKILLVLEFARQVE +AGQLDPTERVVVTAADRLGGWGLAGCADDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP +DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPATACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA +AQPRRIDVDLAMGEAARTAV--- +>[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00048AF0EB +------------DRVSGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE +AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL +PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA +AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA +DPTDASPDDDACQLMADISAR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Pseudonocardia kunmingensis TaxID=630975 RepID=A0A543D0V1_9PSEU +-eELAVEITDRAEQVGVRVWLHAVDVDGGAQF-GIDPGGPVVTASVFKVPVALELARQAV +AGECDLAEPVAVDPGHPTPSPYGLATFPHRSLSWDALATLMIGISDNVATDLVLDRV-GK +PAVAALLDRLGLPGTAVPDNCEELLRVLRPAETCRTTPEEMTRLLALIWRDEAAPAEACA +HVRRWMGRQVW-PHRLRSGFADDVRISGKTGTLP-AVRNEVGVVEYADGGRFAVAVFTRA +RDAQAPERDALIGFAAARA---- +>[subseq from] Serine hydrolase n=1 Tax=Tsukamurella conjunctivitidis TaxID=2592068 RepID=A0A5C5S6Z1_9ACTN +-------------------------------L-SVGGEQPVVPASVYKVLLLVAAARAVD +AGRLDARTRIVVDPAVSTPPTGIATLSDPVEMSVRDLLRSMIAVSDNAAAGVLMRLV-GL +DAVQRTARDLGLHGTRIVGGDAEIHAAYDPTFGSATTAADMTALLAAVWSDTAASTEECA +FARSALAGQVF-RHRIASGFGSAPSIAGKTGTLG-ALRNEVAVVAYPGEYPVAVAVFTHA +ARNDLPRVDAAIGTVAALAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=Amycolatopsis decaplanina DSM 44594 TaxID=1284240 RepID=M2Z5U2_9PSEU +----IATINERAKEVGVRVRLHAAEVDGTRRI-GVDEHTPVVTASVFKVPIALELARQAA +EGGLDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILDRV-RK +EATEKTLRDLGFEHTTVTQDCREVLDALRPEHTCATTAEEITRLLGLIWRDEAAPPAACA +DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVRIFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. 111WW2 TaxID=1945515 RepID=A0A2P8ADH0_9ACTN +-----------------------------DEV-AVGADEPVVIASIFKVLLVLEFARQVT +AGQLDPRARVRVTAGDRLGGWGTAGCADDVELSLRDLALFAISVSDNSAADLLLAQV-GL +DTVRLLVEELRLERTRIVGGPRDVLQVLDPSRTNASTPREITRLLRLIWCDEAGPPQACA +WVRELMSRQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART +RESSRTAVDAAIGTAARIAVD-- +>[subseq from] Beta-lactamase class A n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A1H1QR85_9ACTN +-----------------------------DEV-AVGADEPVVIASIFKVLLVLEFARQVT +AGQLDPRARVRVTAGDRLGGWGTAGCADDVELSLRDLALFAISVSDNSAADLLLAQV-GL +DTVRLLVEELRLERTRIVGGPRDVLQVLDPSRTNASTPREITRLLRLIWCDEAGPPQACA +WVRELMSRQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART +RESSRTAVDAAIGTAARIAVD-- +>[subseq from] Serine hydrolase n=2 Tax=unclassified Chloroflexi TaxID=167963 RepID=A0A5N9HGV3_9CHLR +---LINRMNTMCLESPFQSGWYLKNLQTKESD-NYYGDVVVPSASTRKIAILMNAMKWIH +EGKLSLDQPIRIDETQYVGNSSGCFQYLRPGVQLYDVLTMMIIVSDNTSTGIVANLL-GL +DSINEFSQSIGMIGTTHRHKLPPLDLDHSLDYTNSTTPNDVGLILELILLGTGSSKELCQ +IALDILLNQKL-NNKLPALLPKGTKVAHKTGTGAR-NYNDAGIIFLEDSPLFILTVFTEN +VPTSLADG--------------- +>[subseq from] serine hydrolase n=1 Tax=Bacillus sp. A134 TaxID=2681970 RepID=UPI0012EE580E +-------------------------KSEGNQI-AFNEMKQLRAASIIKLFILAAAYYEKE +RGNIELSKQVNLPDSDMAGGAGVISYLSDKQYTYQQLLELMIIVSDNTATNALIDFI-GL +DYIQAFIKKIHCNNTKLERKLMDE-KAIQLGLENVTTCYDVMLLLDLFTENHIMPKHRQQ +QILTILENQQF-NSKLTASYDSDIKTFHKTGELT-GAEHDAAIFQTADK--LLKAVVLTE +GWANNGEGQQFHQASGAHIYHY- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium RIFCSPHIGHO2_01_FULL_40_15b TaxID=1798594 RepID=A0A1F6I6R6_9BACT +-------LEKFLKGEKGSYSIYYKDLATGQEF-GINENKVLTAGSLNKLLIISYLYNLAR +DNKINLEDKITIQKKDIQDYGTGSLRYDGEGYTLKTLTQLGLEQSDNTAAYVLSLRL-GE +DKIQEYGRKLGLASTNMA--------------NNKTTARDMGKILDLIYSGKITSDPLTQ +ELLDFMKDTDF-EDRLVRDLPSNVSAYHKAADATN-MVHDVGIIDPSGRSPFILAVLTSD +IK-DEEEAKKTIGKIAKFIYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Streptomyces sp. FXJ1.172 TaxID=710705 RepID=A0A176LBP0_9ACTN +---IEDRLEEVFAEAGCKGNVAVLDIDGPGQV-VLGDGELVVAASTFKIAVALELFCQGA +EGRLNLAERVRLSPSQATPGQGFCIFEDEAEVSLRDAARMMMTISDNTATDVLIRRV-SV +PRIHARLAGLGLDRIRLAGTIREEFDSLQPGRVTSATAGQMAALLRLVWRDEAGPGEACA +AVRTILSQQRL-TRKIATGFSAAVRVAAKSGTVPGCVSNDVGVVEFPDGSRFAVAVFTRP +TGPRPPQADPAIGAAARLSVEH- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces prasinopilosus TaxID=67344 RepID=UPI0006E29024 +----------------------------GDGV-GVGADDPVVIASIFKVLLVLEFARQAA +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLARV-GL +DTVRLLAAELGLGRTRIVGGPRDLLEVLDPHRTTASTPREITRLLRLIWTDAAGPPEACA +LVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGGCYAIAVFART +HAASRPTVDAAVGRAA------- +>[subseq from] Uncharacterized protein n=8 Tax=root TaxID=1 RepID=A0A0F4VNV5_9CLOT +-----KEIKKYLETRIGTYAFFFEDLESGFCY-GYNENVQMTSAGCMKLPIAVSAIKYVE +DGKGSFLDKITINEDDKVYGTGIIHEFNNREYTFFELLVAMLIQSDNTAANKLIDIV-GM +DTINEDIQSQGLRNTKLNRKTAD-ERAVSSGVENITSALDLSKIWKHLHNSSFLNEKNST +MLIDILQRQQM-KNKLALYIPDDYEISSKTGDKS-GVENDTALLHLQKG-SFTFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium butyricum TaxID=1492 RepID=UPI00040ECFBA +------EIKKYLETRIGTYAFFFEDLESGFCY-GYNENVQMTSAGCMKLPIAVSAIKYVE +DGKGSFLDKITINEDDKVYGTGIIHEFNNREYTFFELLVAMLIQSDNTAANKLIDIV-GM +DTINEDIQSQGLRNTKLNRKTAD-ERAVSSGVENITSALDLSKIWKNLHNSSFLNEKNST +MLIDILQRQQM-KNKLALYIPDDYEISSKTGDKS-GVENDTALLHLQKG-SFTFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. 13-12-16 TaxID=1570823 RepID=A0A1X4I900_9ACTN +------------------------------EI-AVGADDAVVIASIFKVLLVLEFARQAV +AGQLDPRERVRVTSADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLDRV-GL +DTVRLLAKELGLDRTRVVGGPRDLLEVLDPHHTTASTPREITRLLRLVWTDAAGPPEACA +LVRDLMGRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVARYPDGACYAIAVFART +HDASRATVDAAIGRAA------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces hirsutus TaxID=35620 RepID=UPI0006E449EB +-----------------------------CEV-GIGADDPVVIASIFKVLLVLEFARQVA +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLARV-GL +DTVRLLAAELGLERTRIVGGPRDLLEVLDPRRTTASTPREITRLLRLIWTDAAGPPEACS +FVRDLMLRQIF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGGCYAVAVFART +HA-LAASRPTVDAAAGRA----- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. CT4 TaxID=2320868 RepID=A0A3R5UAS6_9CLOT +-----KEIKKYLETRIGTYGFFFEDLVSGYTY-GFNENVKMTAAGCMKLPIAISIIKEVE +LEKFNFLDKIRIEKEDKVYGTGIIHEFNERDYTIFELLVAMLIQSDNTAANKIIDIV-GM +DRINEIIKEMDLKSTELNRKTNDERH-QHSDVENITSAYDLCVIWKHLYRSTYLSKENST +MLIDILRRQQI-KNKLALYIPDDYDISSKTGDKT-GVENDTELIELNKG-SFAFSVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFCSPLOWO2_01_FULL_39_12b TaxID=1798388 RepID=A0A1F6ARX1_9BACT +--PLKEKIAKALEGTNGIYGVVVRNLKTGETY-SANEHRVFEAGSLYKLWTMTVVINQLE +SGELKEDKVLSQSVSVLNDIEPLAEQTSGTVFSVGNGLKQMITISANLPALLLTEKV-KL +STIATFLTQNGFKESKVGT----------GGEAPTTTPSDMALFFEKLYKGELANQEYTN +KMIDLLKSQQL-NDKLPKYLPQDTVVAHKTGEIGW-FSHDAGIVYSPNGD-YIIVILSES +DSP--PGAEDRIAQVSKAVYEY- +>[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI000368B8F8 +------------DRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE +AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMIARSSNLATNLLLDRV-GL +PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA +AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA +DPTDASPDDDACQLIADISARA- +>[subseq from] KxYKxGKxW signal peptide domain-containing protein n=1 Tax=Streptococcus pneumoniae TaxID=1313 RepID=UPI00136A775D +---IKSEYERLFGNLRGTKSLAIMPTDGTELL-LI-NNNVQRSASTIKLFIMAAAFAKAE +RGELDLSQRYTVKASDIVQASVNLSGAAGKVYTLDNITRMMVETSDNTATNIMINAIGGI +AAVNNEIRRLGYTKTTLNRYMR-IPSQINAGLENYISAIEAADLIKNIYNNSTASDASDR +SMLSKLSNNYY-KLWLPASIQNLAQTWDKPGNDGFGVENDVAIIKRNNRA-YAIALLTQG +TGSNGTTYTNRFAQLGQAIVR-- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00036532C1 +----------HLDRIPATVSAYLARLDAAPTW-TRHPDTTHYAASTMKVAVLVALYRDLA +AGRLAHDTAVPVRNEFDSAQPGAAWDRLGGTAPLRWLAERMIVRSSNLATNLLLKQV-GL +PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRGLALGALATPESCA +AMLDLLVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCSTS +DRPDDEVACQLLADISARAF--- +>[subseq from] hypothetical protein n=1 Tax=Streptomyces rubrogriseus TaxID=194673 RepID=UPI0013DA0D5B +------------------------------------------------------------ +---------------------------------------AAARQRHNTATNLPLDLLGGP +TAVTAFASGLDDATTRFDRNEPQLNSTGPDDERDTTTPAAIVESMRTVPLAGGLQPAGRE +RRTTSLVANTTGDATIRAGVPAGWLIGDRTGTQAQGERNDVGIVLPPDRAPLVS------ +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2568 TaxID=2512219 RepID=A0A4R1WTT4_9ACTN +---------------RGDIGVWLGGLDGHAVF-THDADRAHYSASTMKLPVALAMMRKVD +AGELALDQPVTVHNDFASAEAPATWAKLGEQVPLSWLATEMITKSSNLATDLVLELT-GV +DAANAVLAEYGSGASVIRRGIDDTGA-QAAKISNLMSPADLAAVLVAVGNDKS---ASGE +YVRDLLAGNTW-NGEIPAGVPEGTRVEHKNGWDLR-IRHDGGIVRPSDAEPFVLVVCTTS +DLAD-QDAQKLIAAIAAEAWDH- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium chromiireducens TaxID=225345 RepID=A0A399IP91_9CLOT +------EIKRYLESRIGTYSFFFEDLESGFSY-GYNENVQMTSAGCMKLPIAVSVIKYIQ +DEKGSFLDRVKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIEIV-GI +DNINEDIIAQGLKNTKLNRKTSDE-RATGSGIENITSALDLARIWKHLYNSSYLNEKNST +MLIDILQRQQM-KNKLALYIPDDFEISSKTGDKSS-VENDTALIHTQKG-SFTFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Serine hydrolase n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A2W4N0P6_9FIRM +---LRAEVARFIAGRPQSFGIYFKDLQTGATW-GINERAEIHAASTIKVPLVLYVNRQVA +AGKARMDDRVALRPEDMTGGAGILQRDGFQGYSLRVLTNLAITISDNVATNMLFRHF-GK +DDVGRFMRELGGEVIF------------PG-GRRISTARDMGIYVEAVLDFARRHPLLGA +RILDDMAHSIF-HVGLPGMLPDDVLVAHKEGDIE-GVANDVGIVFSS--RPYILSILSVN +VP-DIDQGFEDIARISKIVYDY- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. LHW51205 TaxID=2248752 RepID=UPI000DE80786 +---VAERVGEIFGRAGVRGCLHVVDVDTGGEV-ALRADEQIVIASIFKIMVVLEFARQAA +AGQLDPTERVLAGAADRLGGWGVAGCADDVEVSLRDLAYLAMSVSDNTAADLLLRRV-GA +DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEHTSSSTARELTRLLRLVWRDEAGPAPACA +MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRA +ERARRIDVDLAMGEAARTAV--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. MOE7 TaxID=1961713 RepID=A0A1W5Y0N6_9ACTN +-----------LARADADIQLHAVDLDTGGQV-AVAADQQVVIASVAKILIVLEFARQAA +SGQLDPGAHLTIRSEDRLGGWGIAGCADDVEISLRDCAYFAMSLSDNTAADAIVRRV-GG +DAVGMLVAELGLERTRFLGGPRHLLRVFDPRRTTSSTARDMTRLLGLIWHDRAGPADACA +AVRRLMTRQLS-STRLASGFPPPVTVAAKSGTLP-GVHMEAGVVRYPDGHRYALAVFATA +RDARPADLDETIGRVAHAAVQ-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=A0A1D7VY48_9ACTN +--------------------LHAVDLDTGGEV-AVAADQQVVIASVAKILIVLEFARQAA +AGQLDPGAHVTLRAEDRLGGWGIAGCADDVDISLRDCAYFAMSLSDNTAADALIRRV-GG +DAVRMLVAELGLDRTRFLGGPRHLLRVFDPRRTTSSTARDMTRLLGLIWHDRAGTADACA +AVRRLMTRQLS-STRLASGFPPPVTVAAKSGTLP-GMHMEAGVVRYPDGRRYALAVFATA +RDTRPADLDETIGRVAHAAVE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces prasinopilosus TaxID=67344 RepID=UPI0009423E7C +----------------------------GDGV-GVGADDPVVIASIFKVLLVLEFARQAA +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLARV-GL +DTVRLLAAELGLGRTRIVGGPRDLLEVLDPHRTTASTPREITRLLRLIWTDAAGPPEACA +LVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGGCYAIAVFART +HA-LAASRPTVDAAVGRAA---- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora auratinigra TaxID=261654 RepID=UPI000B8575BA +--DVAQRIAEIFGRVGVDGCLHVTDVDAPRREiAVRADEQIVIASVFKILLVLEFARQAV +AGQLDPTERVLVRAADRLGGWGVAGCADDVEISLRDLAYFTMSVSDNTAADLLLRRV-GP +DVPPMLAAELGLARTRIRGGPRELVEVFDPAHTTSSTARELTRLLELIWRDEAGPPAACA +MVRDLMARQLF-WTRLAAGFPPGVRVAGKTGNLP-GLHLEAGVAEYPDGGRYAVLVHART +RRLSRIDVDLAMGEAARVAV--- +>[subseq from] Beta-lactamase n=2 Tax=unclassified Pseudonocardia TaxID=2619320 RepID=A0A1Q8LKT3_9PSEU +-----------------------------RDV-DAGAHAPVVMASVYKLFVLVAYCREVD +AGTVDPREPVVVPVPRTPGLTGISALADPVTMSWRDLVTSMVTASDNAAADVVHSRV-GR +DRVAALPAELGLSGTRIRGGTDDVFAALSPVYGSATTAADVTALLALLWRGELASEASTA +FARLLLGAQIW-PHRLRAGFPAPTQVAGKTGTVG-AVRNDVGVVTYPGEHPVAVAVFTHS +ARTTVPRADAAIGAAARVAVH-- +>[subseq from] serine hydrolase n=1 Tax=Megasphaera cerevisiae TaxID=39029 RepID=UPI000A8BCB5F +----------------VHVSLYVRPLDEARPF--IYNERVMPSASLIKVPIMAEAFRQEK +EGRIRFEDMLLVY--DPVEGGSFYGGPPDRKVSLYDLIFHMIVESDNTCANMLMDIL-GA +DRINEGFLRWGMDHTILRRKMMDFAAA-RAGRENMTTVSDMGRFFTLLADGRCVDEERSQ +AMLAILSQQED-NAILPAQIPHSVRVDHKTGELE-GIYHDCGIVYSPRR-VYICCMMADG +IT--------------------- +>[subseq from] serine hydrolase n=1 Tax=Oceanobacillus sp. CFH 90083 TaxID=2592336 RepID=UPI00128E8E44 +------------------------IQSGENQI-AFNEQEQLRSASIIKLFILAAAYYEEE +RGNLDLSKQICIPSSNIAGGAGVIAYLSGKQYTYQQLLELMIIVSDNTATNELIDFI-GL +DNIHAFIQKIHCNNTKLERKLMD-EEAMKLGLENRTTCYDVMLLLNLFTENNILPTYRQD +QILTILENQQF-NSKLTAAYDSTIRTFHKTGELT-GAEHDAAIFQTADK--LLKAVMLTE +GWTNNGEGQQFHQAAGARIYQY- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=A0A193C0J7_AMYOR +---VIETINARAKEVGVRVRLHAAEIDGTRRI-GIDEHTPVVTASVFKVPVALELAKQAA +EGVLDLGEPVTVPPGHPTPPYGLATFRHEVTMSWHDLAILMIGISDNVATDLILDRV-GK +EATGETLRRLGFEHTTVSQDCGETLSALQPAQTCATTAEEITRLLGLIWRDEAASPTACA +DVRRWLELQVW-PHRLRSGFPDGIRVSGKTGTLPT-VRNEVGVVEYPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAARA---- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces prasinopilosus TaxID=67344 RepID=A0A1G6XBE0_9ACTN +----------------------------GDGV-GVGADDPVVIASIFKVLLVLEFARQAA +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLARV-GL +DTVRLLAAELGLGRTRIVGGPRDLLEVLDPHRTTASTPREITRLLRLIWTDAAGPPEACA +LVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGGCYAIAVFART +HA-LAASRPTVDAAVGRAA---- +>[subseq from] Beta-lactamase (Class A) n=1 Tax=Bifidobacterium callitrichos DSM 23973 TaxID=1437609 RepID=A0A087AB87_9BIFI +------------------------------------------------------------ +-----------------------------DNATIDANLQQMITVSSNDAANRLLAVIGGK +GGTTAAIATVTDTAVRYGSGTKELRAASGNAVENWTSARDCGTFLAKVYRGELVSANASK +RMVDLLLGQTR-RTKIPAGVPAGVQVANKTGELA-AVQNDVAIVYG--ARPYVIAVMTND +VDESAATN---ITTLSANVY--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces prasinopilosus TaxID=67344 RepID=UPI00099EB05C +----------------------------GDGV-GVGADDPVVIASIFKVLLVLEFARQAA +AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLARV-GL +DTVRLLAAELGLGRTRIVGGPRDLLEVLDPHRTTASTPREITRLLRLIWTDAAGPPEACA +LVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGGCYAIAVFART +HA-LAASRPTVDAAVGRAA---- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis thailandensis TaxID=589330 RepID=A0A229S1R2_9PSEU +---VIATINARAKEVGVRVRLHAAEIDGARRI-GIDENAPVVTASVFKVPIALELARQGA +EGELDLGEPVTVPAGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILARV-GK +EATAKTLRRLGFEHTTVPQDCREVLDALQPAHTCATTAEEITRLLRLIWRDEAASPSACA +DVRRWLDLQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEHPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Micromonospora sp. 4G51 TaxID=2202420 RepID=A0A317DTW2_9ACTN +----------------------------GREV-GVRADEQVVIASVFKILLVLEFARQVA +AGQLDPTERVLVRADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DVVPMLAAELGLSRTRIVGGPRQLVEVFDPAHTTSSTVRELTRLLGLIWRDETGPPAACA +MVRELMGRQLF-WTRLASGFPPGVRIAAKSGTLP-GLHLEAGVAEYPDGGRYAIAVSTRT +ERLDTRDVDLAMGEAARVAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Paenibacillus spiritus TaxID=2496557 RepID=A0A5J5GAI1_9BACL +----------------------------------LGKDDTYKPASTIKMALVSALMQQVD +NGTLKLSDTVTVEPADVVGGTGSLQKESPKEVTLERLARLMITQSDNTATNVLIDVV-GL +DKVQALMDKLGLKVMHLGRKMFAS--APTPEQDNYINAADLVTLLEKIYDGTFLTTASRN +QIITWMAAQEV-NTKFGTALPD-------------------------------------- +----------------------- +>[subseq from] Beta-lactamase class A-like protein n=1 Tax=Candidatus Roizmanbacteria bacterium GW2011_GWC2_41_7 TaxID=1618487 RepID=A0A0G0XCY3_9BACT +---LSLAIRNRIAEEEGTYSIRFEDFGTKNAF-GINDEPVVTAASVIKIPALAALYYLAE +QRDIDLNEVITIPESDMQRGTGIIRQDAGATYTIRELAQVMMEHSDNTAVYVLANRVIGL +ERLQELIDSWGLSNTNYL--------------ENNISNKDMNKVMRMMYSGELVKDEENV +EMMGWMDDSDF-EERLPKYIPEEVSVYHKIGNEVR-ITHDVGVIDLPEK-PYYLGVLGIE +IP-DHEHATEVIAQISQMVFEY- +>[subseq from] Beta-lactamase class A-like protein n=3 Tax=Microgenomates group TaxID=1794810 RepID=A0A0G0T751_9BACT +---LSLAIRNRIAEEEGTYSIRFEDFGTKNAF-GINDEPVVTAASVIKIPALAALYYLAE +QRDIDLNEVITIPESDMQRGTGIIRQDAGATYTIRELAQVMMEHSDNTAVYVLANRVIGL +ERLQELIDSWGLSNTNYL--------------ENNISNKDMNKVMRMMYSGELVKDEENV +EMMGWMDDSDF-EERLPKYIPEEVSVYHKIGNEVR-ITHDVGVIDLPEK-PYYLGVLGIE +IP-DHEHATEVIAQISQMVFEY- +>[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. MD30 TaxID=2033437 RepID=A0A249SY32_9BACT +--SLQRQIAGFAAESGGEVGVAAKNFATGLEV-RYRDSARYPMQSTFKFPIAMAVLHQVD +EGRLLLEQPIYLDRKWMVPWSPLRDSFPKGNVPLSKLLTLMVSQSDNIACDILIDLIGNE +AMINDYIHKLGVKDLAIVANEAKMHAGWEVQYSNWC------------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. NRRL B-16309 TaxID=1519494 RepID=A0A0N0AHC3_9ACTN +-------------------RVHVRDIDGTGEL-GHRADEPLALASVAKILITLEFARQAA +TGALDPAERVVARRQDRLGGSGTAGFADDVELSLRDCANLAMTISDNTAADLIEERV-GT +EPVHLLVRELGLEHTRFTGGPRALLRH-PPDPATSSTPRDLTRLLQLVWTDAAAPPRACA +FVRELMARQLV-RARLASGFAPPVHVSGKTGTLP-GLRMEAGVVEYPDGHRYAVAVAAVG +AEGNGHEVDAALGRAARAAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Oceanobacillus sojae TaxID=582851 RepID=A0A511ZQX6_9BACI +-------------------------KSEGNQI-AFNEMKQLRAASIIKLFILAAAYYEEE +RGNIELSKQVNLPDSDMAGGAGVISYLSDKQYTYQQLLELMIIVSDNTATNALIDFI-GL +DYIQAFIKKIHCNNTKLERKLMDE-KAIQLGLENVTTCYDVMLLLDLFTENHIMPKHRQQ +QILTILENQQF-NSKLTASYDSDIKTFHKTGELT-GAEHDAAIFQTADK--LLKAVVLTE +GWANNGEGQQFHQASGAHIYHY- +>[subseq from] Serine hydrolase n=1 Tax=Kribbella sp. ALI-6-A TaxID=1933817 RepID=A0A1V2P0M9_9ACTN +---------------RGAFGVWLGRLDGAAVF-THDADRPHYSASTMKLPVAMAMLRKVD +AGELALDQPVTVHNDFASAEAPATWTKLGEQVTVDWLATEMITRSSNLATDLVLEQV-GV +DAANAILLQYAGDASAIRRGIDDVAAQ-AAGISNLMTPAGLAAVLVAAGNDDG---ASGK +YLRDLLAANEW-NGEIPAGVPAGTRVEHKNGWDVR-IRHDGGIVRPADAEPFVLAVCTTS +ELAD-PDAQKLIAAIAGEAWA-- +>[subseq from] serine hydrolase n=1 Tax=Clostridium sp. C8-1-8 TaxID=2698831 RepID=UPI0013722E28 +-----KEIKKYLETRIGTYGFFFEDLVSGYTY-GFNENVKMTAAGCMKLPIAISIIKEVE +LEKFNFLDKIRIEKEDKVYGTGIIHEFNERDYTIFELLVAMLIQSDNTAANKIIDIV-GM +DRINEIIKEMDLKSTELNRKTNDERH-QHSDVENITSAYDLCVIWKHLYRATYLSKENST +MLIDILRRQQI-KNKLALYIPDDYDISSKTGDKT-GVENDTELIELNKG-SFAFSVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Mycobacterium sp. QIA-37 TaxID=1561223 RepID=UPI0007A0E779 +-----------------------------PIV-DVDGDRPAVAASVYKIFVLIAAARAFD +SGHLHPEATVRVVPADCTPGPTGISTFSNPVLSWLDLARLMITHSDNTAADVLLAAI-GL +DTVNELTEELGFNSTRIIGGTSALQRAFDPAYTTATSACDTDRALSAIWTGTATSAQSSD +MMKQILTQQIS-QHRIRSAFPRDVTVAGKTGTIGP-IRNEVAVIAFPGEPPMAVSVFTRA +ARADLPNVDRAIGQAARIAI--- +>[subseq from] Uncharacterized protein n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A644ZZH6_9ZZZZ +----------LDEERDGKYSFYFEDLDGAYTY-GYNQDVPQTSAGCMKLMLAVAFLKKVE +EGMFSMDELVPIKDEDKKPGSGILYEFIERTYTIRELISSMLVVGDNTATYKLMTLL-GV +DQINIMFREMGLTHTHISN--------LPGNESNTTTASDMAKIIKLLYQKNYLTEKHSD +YIIDLIRRRV--KSKIAFYLPNKVRFASKTGDAP-GIENEVALINTESGN-FVFSIMSHD +LPNS-VYGMISLAKAGM------ +>[subseq from] serine hydrolase n=1 Tax=Nocardia sp. CT2-14 TaxID=2675850 RepID=UPI0012B86802 +------------------------------------------MSSVVKVPLVLEFARQVA +AGQLDPTDRVRATAANRLGGVGTAGCHDDVEFSLRDAAYFALTVSDNTAADLLFDRV-GV +DNVRSLARELGLGATRIMGSLRDILYAVDPLRTTAGTARDMTRMLWLIGEDRAGSPEACR +FVRDLMRQQVY-GHRLPSAFPAGTDIWSKTGTLP-GIRNEIGVVGYPDGSRYAVAVFTVS +HSGRQPAVDRAIGAAARAAIE-- +>[subseq from] serine hydrolase n=1 Tax=Sciscionella sp. SE31 TaxID=1445613 RepID=UPI0004DF3807 +----EDEIIARAEQVGVRVRMHARAIDGTASF-GIGADEPVVTASVFKVPLAVELADQAE +RGHCDLAEQITVPAGPKVPPYGLATFRHPVTLSLDALATLMIGISDNVATDLVFAKI-GK +PAVRALLDRLGLAGTVLEQDCAELLGALDPAQTCRSTAAEMTALLGMIWRDEAAGPGACA +DVRRWLGLQVW-PHRLRSGFHDEVRISGKTGTLPT-IRNEVGVVEYAEGSRFAVAVFTEA +VDSQAPERDAFIGFAAARAIE-- +>[subseq from] hypothetical protein n=1 Tax=Serinicoccus profundi TaxID=1078471 RepID=UPI000255E558 +----------------------------RHEV-SYAADDLVPMASLYKVLLALAWARLVD +AGDLDPRARHTVSAPDRTPGPTGLSSLEDEVVSQRDLVTLMLTVSDNAAADVLLDLV-GL +PRLREVAADAGMTATTLHGGTRHHQRVYDPAMSSTTTTRDMTRLLGALWREELVAPESGV +RIRRSMARQVF-RHRLASGFPDDVEIASRTGSLL-ALRHEVGVVTFPGEEPVVVAVLTQA +LNQHLPDVDRAIGEIGRVAV--- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis pretoriensis TaxID=218821 RepID=UPI000A3CD601 +---------------------------------AVGADDPVVLASVFKIPVAVAYAREVV +AGRLDETERTRVGPRYRIGGIGTAGCADDVELSWRDLALFMLTMSDNAATDVIYHRV-GQ +EAVDRVLTDLDLHRTRLIGCCEDLFAVLDPERTTASTPREITTLLEAIWTDRAGDAAACE +RVRTIMAQQIW-PHRISSGFGSDVRIAAKTGTLP-AVRNEAGVLSYPDGRRFAVAVFTRA +DSERQPAVDAAIGKAARLAVDH- +>[subseq from] serine hydrolase n=1 Tax=Serinicoccus profundi TaxID=1078471 RepID=UPI000495057B +----------------------------RHEV-SYAADDLVPMASLYKVLLALAWARLVD +AGDLDPRARHTVSAPDRTPGPTGLSSLEDEVVSQRDLVTLMLTVSDNAAADVLLDLV-GL +PRLREVAADAGMTATTLHGGTRHHQRVYDPAMSSTTTTRDMTRLLGALWREELVAPESGV +RIRRSMARQVF-RHRLASGFPDDVEIASRTGSLL-ALRHEVGVVTFPGEEPVVVAVLTQA +LNQHLPDVDRAIGEIGRVAV--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID3343 TaxID=2690260 RepID=UPI0013680E74 +----------------CGGTLCVRSLDSGAEF-ALRADESVIPASVVKVQIALEAETWFA +DGRLDPRERVTLSVADRTPGPGVSLFDDDAEMSWRDLVVLMLTISDNHATDVLLRRV-GV +GAVNATAARLGLLGTVIESDLRTMLDALDPQWGTRTTAYDMVDLLQAIWTDRAGPAAACE +RVRATMAKQVT-RHRIAGGFRTPVRVAAKSGSLVGVIRNEIGVISHPDGSRYAAAVFTRS +RPADDAAINDGIGTATAMAVD-- +>[subseq from] Beta-lactamase regulatory protein BlaB n=2 Tax=Streptomyces sp. YIM 121038 TaxID=2136401 RepID=A0A5B7V3I4_9ACTN +-------------------------------V-SLAADTPVPVSSVFKVLLVLEFARQVA +AGQLDPRERVLVTDGQRLGGWGIAGCEDDVEVSLRDLAYFALTVSDNSAADVLLSRV-GL +DTVGMLARELGLARTRIVGGPREALAVLDPGRANASTPREVTRLLDLIWRDAAGPPEACA +RVRALMGRQVF-RHRLTSGFPDDVRIAAKTGTLP-GLHIEAGVVRWPEGDTYAVAVFARS +HAADLTRVDAAIGTAARIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. WMMC415 TaxID=2675222 RepID=UPI0012B455BC +------ALDAHLDRVPGTVSAYVGRLDTPPTW-TRHPDATHYAASTMKVAVLVALHRAAE +AGRLDLDAPAPVRNESALPGAPRFWDRAGGAAPLRWLAERMIVRSSNLATNVIIDQV-GL +PAVADVWARAGARHSVTGRGIEDFAA-RDAGITNLVTAADLAALLGGLARGRLAAPESCA +AMLDTLAAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHGVGVVAPDDAPPYVIAVCTTT +DAADEDDACRLIARISREAWN-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora taraxaci TaxID=1316803 RepID=A0A561VZ01_9ACTN +------DLDAHLDRVPGTVSAYVGRLDAPPTW-TRHPDAAHYAASTMKVAVLAALHRAAE +AGELDLDAPVPVVNEDSAQGAPRFWDRLGDTATLRWLADRMIVRSSNLATNVVIGHV-GL +PAVADVWASTGARNSVTGRGIEDFAAR-EAGITNTVTAADLAALLGALAAGAIASPAACT +AMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVLPDDAPPYLIAVCTTT +DPDDADDACLLIADVSARVWA-- +>[subseq from] serine hydrolase n=1 Tax=Rubrobacter sp. SCSIO 52915 TaxID=2653852 RepID=UPI00140727D7 +----------SAGRYAGRYGVVVFDPESGSGV-SLGGGEAFTAASVGKLPTLISLYRAAA +RGELSLDEKISLLPGDYQSGTGVLHNFAPGTMTLRECAYFLVNKSDNTAWAMLDRRL-GV +ENIQAEMREIGARGTDYDMG--------------VTTPEDVFLMLQKISDPAFTDGELSG +EMISAMTDTAF-EDRIPAPLPPDVRVAHKIGSYED-SYGDAGIVFYKDRRRYFIVVLSGG +TGE--GSARAAMQEISRVAYE-- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Clostridium sp. TaxID=1506 RepID=A0A3D4FKU0_CLOSP +-----KEIKRYLDNRDGIYSFYFEDLKSGYTY-GLNENVQMTAAGCIKVPIAVALMKEIE +NNNFNIDDKVSITKNDMVSKYSIIHEFSEKEYTIKELLIAMLIQSDNTAACKIVNLV-GM +DRINELIKDMKLYSTEVRKYPSEN--KIDDNKENVTTSHDLSKCLRLLSNNSYLNQEHSN +LILETLKKNQV-NTGIPFYLPHELQTANKIGTLKC-VENDTALLNLPKGN-FVFTVMSSN +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Terriglobus roseus TaxID=392734 RepID=UPI0009F6C4F0 +--EPEAAIRQVIAQHHGSIALYAHQLNTGKTI-SIDADKPVQTASTIKLALLWTALREIS +LGRATWDEKVTLKPREGVAGSGILHFLDTPVLTLKDVATMMVIVSDNTATNLMIDRF-PT +KLVDDNMAALGYAETWLYKKVFKPADDQPKFGLGKTTPKQIGQLMEKIGRCDTKADAACN +VAIDMLRNQFY-RDTIPRYLERGSGIASKTGSLD-ATRSDVAIIAAKSG-PIVLAVYTYD +NADKDNEGEVAIAKIAQAVVEAw +>[subseq from] serine hydrolase n=2 Tax=Agromyces sp. HY052 TaxID=2585717 RepID=UPI001116D5FD +-qALRERIGSIEAELGVTATMHAIDVDTGEEF-GVAADDLVVPASIFKVPVLTELCCRFA +DGSIDPAQGMFIAREAFRTL---SSVFLDDVLSVRDLAVSMMSVSDNRATDILIDLL-GL +DAINERSRRLGLEQTVLVEDCAGLFRVLDASATNRTTPREVTASLALLWDGGVLAPAATA +EARRILSLQVW-PHRLKAGFPSRIRISGKTGTLPY-LRNEAGMIEYPDGGRYAVAVFVRE +TLEENIDADRSIGLIGRAVVDE- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. CV4 TaxID=2478711 RepID=A0A3L7BSM5_9ACTN +---------------------------GGPEV-GVRADEQVVIASIFKILLVLEFARQVV +ADQLDPTERILVTAADRLGGWGLAGCTDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLTRTRVLGGPRDLVEVFDPARTTSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMARQIF-WTRLAAGFPPGVRMSGKTGTLP-GLHLEAGVAEYPDGGRYAIAIFARA +DQPRRIDVDLAMGQAARTAV--- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6MLC9_9BACT +--TLEAEIRRIANAAGGEVGVAAWRLDSGPRM-LLNADEAFPMASTFKVAVAGALLGKVD +AGTLSLGTVLPVDKSRYVESEVIADAFIHSGLSIHNLLEVMLSRSDNTATDVLTSAAGGP +GAVTAWVRAQGITGLRVDRDTAGIVRAFDKDPRDSSTPDAMA------------------ +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Kocuria TaxID=57493 RepID=UPI00118427F8 +-------VTGILRDATGAVAVRVIDAPELPAF-GWRADEAFPAASLYKLVVMVAFCRAVD +RGDLDPTALVTLRPEDRADPTGLAICQDPVRISWRDLVRLMMTVSDNAAGQAVLREV-GH +ARVRDVLREMGLSSTVVRPG-PAPDAGYDPLLVSATTASDLVALLCAIWQDRAASTAQCA +FMREVMSQQAWGHRFAEAFSYPGAGVAAKTGSFG-ALCHEAGVISHPGEKSIAVAVLTRS +VRRQIAVSNRIVGQIARHCVRSy +>[subseq from] Beta-lactamase class A n=1 Tax=Terriglobus roseus TaxID=392734 RepID=A0A1H4J542_9BACT +--EPEAAIRQVIAQHHGSIALYAHQLNTGKTI-SIDADKPVQTASTIKLALLWTALREIS +LGRATWDEKVTLKPREGVAGSGILHFLDTPVLTLKDVATMMVIVSDNTATNLMIDRF-PT +KLVDDNMAALGYAETWLYKKVFKPADDQPKFGLGKTTPKQIGQLMEKIGRCDTKADAACN +VAIDMLRNQFY-RDTIPRYLERGSGIASKTGSLD-ATRSDVAIIAAKSG-PIVLAVYTYD +NADKDNEGEVAIAKIAQAVVEAw +>[subseq from] Extended-spectrum beta-lactamase VEB-1 (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=V9Y0V6_ACIBA +------------------------------------------------------------ +-----------ITPQDLLPWNPIKQEHNGTTLTIEQILNYTESQSDNIGCDILLKLLGGT +DSVQKFLNANHFTDISIKANEEGMHKDRNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD +FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPN------------ +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora echinospora TaxID=1877 RepID=A0A1C4YIG8_MICEC +--------DARLAGVPGTVSVYAGRLDAAPTW-THAEHTPHYAASTMKVAVLAALYRAAE +AGALDPDTPVPVHNDFPSADGPRFWDRLDRTATLRWLAERMIVRSSNLATNILLGHV-GL +PAVAEVWALAGARHSVTGRGIEDYTAR-AAGITNLVTAADLAALLGALATGAIATPANCA +TMLDVLRAQEF-REDLPAGLPAGVPIAHKNGWVT-GVRHGVGVVLPHDAPPYVLAVCTTT +DL-TDPDACRLLADVSVRVW--- +>[subseq from] serine hydrolase n=1 Tax=Embleya hyalina TaxID=516124 RepID=UPI000F819BF1 +---VRGRIGAAFADAGVTGALHAVDIDAGREV-EVGADTLYSTASLHKLCLVTTLFREAA +AGRVELTRRIELPAGPGRSGTGVAAMLDPVTMSLRDLASLTVAVSDNAAADALWDEL-GL +DTVNATMVDLGLTRTVAIEPLRELYAALDPNRSNRGTPRDLTRLLAAIWRDEACGGEYGA +GLRRVLGLQAW-SHRLASGFPDDVRVSGKTGTLPT-MRHEAGVVEYPDGGRYAITVCTRS +ADAALPAADAVIGTVGRLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Actinocatenispora sera TaxID=390989 RepID=UPI0004C366A6 +-----------------------------------AATEPVVLASMVKVPLVLEFARQVV +AGQLDPTTRVRLRAADRLGGSGTAGCADDVEMSLRDLARFALSISDNTAADALFAAV-GV +ANVRSLVRELGLADTRIIGGPRQVVAALDPSRTNASTGRDLTRLLAAVWRDEAAPAAACA +MLRGLMATQLT-AHRLASGFPDEVEVVGKTGTLL-AVRAEAGVVSRPDGGRYAVAVGIRL +DRGRQPAADRALGTAA------- +>[subseq from] Beta-lactamase class A n=1 Tax=Asanoa ferruginea TaxID=53367 RepID=A0A3D9ZV96_9ACTN +-----SRIAGIFDAVGVDAQLHAVDIDGGAEL-ALRADEPVVLASIFKILLVLEFARQAV +AGQLDPTERVIVRAADRLGGWGTAGCADDAELSLRDLAYFAMAFTDNTAADLLMRRV-GP +DVLPLLAAELGLTGTRVIGGPRELLEVFDPARTTSSTPREVSRLLGMIWRDEAGPPAATA +MVRGLMARQIF-WTRIQSGFPPEVRVSAKTGTLP-GLHMEAGVVEYPDGGRYALSVFALA +RLGAEARRDLAIGEAARTAV--- +>[subseq from] Beta-lactamase class A-like protein n=1 Tax=Candidatus Levybacteria bacterium GW2011_GWA2_40_16 TaxID=1618458 RepID=A0A0G0RIQ7_9BACT +-------IGKFLKTIKGTYSIYYKDLKTGEEF-GIDENKVLTAASLTKVLIIAYLYNQAN +KGKINLEDKIVIQKDDIQDYGTGSIRYEGEGYSLKQLIKLALEQSDNTAAHVLVLKL-GE +DKIQKFGEKLGFSATKMK--------------ENKTSAQEMGRLFELIYLRKITSEPLTR +EFLDFMKDTDF-EDRLARDLPSNVAMYHKAADATN-MVHDAGIIDPGGKNPFILSILTEN +IA-SEEEAKKNIGKLAKFIYDQ- +>[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=bacterium HR26 TaxID=2035421 RepID=A0A2H5YVL2_9BACT +-----------------------RNLTDGTEA-AVQPDRVFYAASLYKLAILYEVYRQER +QGRIDFSQTLTITEKAAEQTLDLLGWSAGSVITVAQAVEAMITVSDNASAVLLGDLV-GW +HNVDQGLRELGLRSTRVNDPELP------------VTAADLAWLLDRMACGQAVDEQASR +EMVELLTRQRV-RDRLPALLPEGVVVANKTGNWTN-ATHDAGIVYSPRA-TYVIVVLSET +AWQS-----EPIARLSAAVYAYf +>[subseq from] serine hydrolase n=1 Tax=Megasphaera cerevisiae TaxID=39029 RepID=UPI0009D2199C +----------------VHVSLYVRPLDEARPF--IYDERAMPSASLIKVPIMAEAFRQEK +EGRIRFEDMLLVY--DPVEGGSFYGGPPDRKVSLYDLIFHMIVESDNTCANMLMDIL-GA +DRINEGFLRWGMDHTILRRKMMDFAAA-RAGRENMTTVSDMGRFFTLLADGRCVDEERSQ +AMLAILSQQED-NAILPAQIPHSVRVDHKTGELE-GIYHDCGIVYSPRR-VYICCMMADG +IT--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. AcE210 TaxID=2292703 RepID=A0A371XNZ3_9ACTN +--ELIETITARAAEVGVQVWLHAADLDSPRHV-GIDADEPVVTASVFKVPVAVELARQAA +DGELDLAERITVPPGHPTAPYGLATFRHDVTMSWYDLAVLMIGISDNVATDLILGKV-GK +AAVAGTLRRLDLPHTAVPHDCGDLLRALTPEETCRTTAAESTRLLGLIWRDEAAPATACA +DVRRWLELQVW-PHRLRSGFADDVTISGKTGTLPS-LRNEIGVVEYPDGGRYAVGVFTRA +VDSRVPERDAFIGFAAARAV--- +>[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. TaxID=1506 RepID=A0A3D5MZA1_CLOSP +-----KEIKKYLESRIGTYSFFFEDFESGFSY-GYNENVQMTSAGCMKLPIAVSVIKYVQ +DGNCSFLDRIKIEENDKIYGTGILHEFDNRDYTIFELLVAMLIQSDNTAANKLIDIV-GM +DTINEDICSLGLKNTKLNRKTSD-ERAVSTGIENITSAYDLSRIWKVLHKAEFLDEKNSQ +MLIDILQRQQM-KNKLALYIPDDYEISSKTGDKT-GVENDTALLHLQKGD-FTFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Saccharothrix sp. NRRL B-16348 TaxID=1415542 RepID=UPI0006AFC8A8 +----AARVRAAFADAGVTGALHAVDLDHDREL-SVGADEPVVLASVFKVPLLVALHHSAH +----DLTRRITLDADRSTGPTGVGGMLDPVTMSLRDLAYLAVTVSDNAAADALADLI-GL +DAVNDTLRELGLTRTLVVHRARDFMRALDPDHTNRGTARDLTTLLRHVWRHDDC-----A +PIRRAMALQVW-PHRLASGFPDDVRVAGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRS +ASFTLPAADAVIGTAARLALEH- +>[subseq from] serine hydrolase n=1 Tax=Agromyces sp. Root1464 TaxID=1736467 RepID=UPI0006F5E3E0 +--ALLRDAAEVLRSAGLRASIVVRDLGSGREL-SLAGEDTYPLASVVKLPLALAVLQRID +EGRLDPARPVTLRPDDRTPLVGYCRFQHPTTVAVADLLYMAVCLSDDTAADALFDLC-PP +AAVTASLREAGITGITVRHSIRELHRQLDVSSANAGTANACVELLDRIWRSPALAPQ-QD +RLRGLLAMNVM-RQRLAPDLEDDAVWHSKTGTFLH-LRHEIGVLEHADGRAIAIAVLSES +SVQRQPAAEQALGLAAKLL---- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI00041DA7CE +---VIETINARAKEVGVRVRLHAAEIDGTRRI-GIDEHTPVVTASVFKVPVALELAKQAA +EGVLDLGEPVTVPPGHPTPPYGLATFRHEVTMSWYDLAILMIGISDNVATDLILDRV-GK +AATGENLRRLGFEHTTVSQDCGETLRALRPERTCATTAEEITRLLGLIWRDEAASPTACA +DVRRWLELQVW-PHRLRSGFPDGIRVGGKTGTLPT-VRNEVGVVEYPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAARA---- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. TSRI0369 TaxID=1703936 RepID=A0A1Q5H4Y7_9ACTN +---VAERVGEIFGRAGVRGCLHVVDVDAGGEV-ALRADEQIVIASIFKIMVVLEFARQAA +AGQLDPTERVLAGAADRLGGWGVAGCADDVEVSLRDLAYLAMSVSDNTAADLLLRRV-GA +DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEYTSSSTARELTRLLRLVWRDEAGPAPACA +MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRA +ERARRIDVDLAMGEAARTAV--- +>[subseq from] serine hydrolase n=1 Tax=Auraticoccus sp. F435 TaxID=2656650 RepID=UPI0012E77B93 +---VADDIRQEWRRAGLSGGFLARHLDSSEQL-GFEVDRAVPLASVAKVPLALVAYDQIV +AGQLDPAQPVELRPEERTLGPTGLSLEHPCTVAVGDLITMALAVSDNAATDALMRFV-PP +AEVTRRMRQWGWHDITLRHHIHELNTQLDTSHANTGTAAALVRLLEAVWTDRVSVPAATA +RLRRTMAHQPS-HRRLGAELIDLTSVVGKTGTFLN-LRHEIGVVTTADGDRVAVAALTVS +SVGEQPEVDAAIGAAARVAVE-- +>[subseq from] helix-turn-helix domain-containing protein n=1 Tax=Streptacidiphilus carbonis TaxID=105422 RepID=UPI0007C6B94B +----GAALQRIFAEADAELHVRALD-GDPGEV-SFGADTPVVLASVFKIAVALEYARQAA +AGTLDRTQRHTVTRAHRSGGAGSDGCQDDVELSLRDAAFLMMSASDNAATDLLLERV-GA +RNVRDTVAGLGFTRFRLGGSCREGAAYLDPAHGRAGTPREITALLAAIWRDEAGPAEACA +EVRELMSRQFQ-SHRLESGFPPQVRVAAKNGTHW-GIRNEAGVVEYPDGHRYAVAVFLRT +RSERLPAADAAIGRSARTAIDH- +>[subseq from] serine hydrolase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=UPI0009E0616E +--RLSKSINKIAQEHQGHLGIAIEW--KGQFF-FLNERDVFPSASLIKLPIMIEGFMQSL +SGTLELDELIRVDNIRKAGGAGIVQYISPQSLSIGDLLTSMIIVSDNMATNYLIERL-GL +ESINSRCQQLGMSNTVLQRKMMDQQA-RERKLDNYTSPLDIIRCLKAIQND------KNQ +SAKRILSNQQL-LDKLPYYLGRSIRIANKTGELDK-VEHDCAIIEYEDE-IIYVAILTDQ +LP-TNQKGKEIIQLIGASIFE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2500 TaxID=2512214 RepID=A0A4R2CQZ0_9ACTN +---------------RGDFGVWLGGLDGHAVF-THDADRAHYSASTMKLPVAMAMMRKVE +AAELALDQPVTVHNDFASAEAPATWAKLGEQVPLGWLATEMITKSSNLATDLVLELT-GV +DAANAVLAEYGSGASVIRRGIDDVGAQ-AAKISNLMSPADLAAVLVAVGNDKS---ASGE +YVRDLLAGNTW-NGEIPAGVPEGTRVEHKNGWDLR-IRHDGGIVRPPDAEPFVLVVCTTS +DLAD-QDAQKLIAAIAAEAWDH- +>[subseq from] Beta-lactamase n=2 Tax=Thermaerobacter marianensis TaxID=73919 RepID=E6SHA2_THEM7 +-----EQVRAFIATRPQTFGIYFKDLQTGATW-GINEREPIHAASTIKVPLVLYVNHQVA +AGRARMDDRVVYEPDDLVGGAGILQRFPGKSYSLRILTNLSITISDNVATNMLFRHF-GK +DNVGAFMRSLGGEVIFP-----E--------GRRISTARDMGRYVEAVLDFARRHPLLGG +RMLDDMGHSIF-HVGLPGLLPQKVFVAHKEGDIA-GVADDVGIVFSD--RPYVLAILSKG +VD-DIDRGFEDIARISKIVYD-- +>[subseq from] serine hydrolase n=1 Tax=Pseudonocardia sp. N23 TaxID=1987376 RepID=UPI000BFC461A +---------------------------SEREI-DVGADVPVVMGSVYKVLVLVAFCRAVD +AGDLDPREQVTVEPGPRTPPTGISALTDPVTMSWRDLTRSMITVSDNAAADVVHARV-GR +DRVAALPTELGLPGTRVRGGTADAYALLSPAFGSSTTAADSTRLLTLLWRGELASAAGTA +FARRVLTAQVA-PHRMRTGFPGTAAVAGKTGTIG-AVRNEIGVVTYPGEHPVAVAVFTHA +ARATVPRADAAIGVAARAAVN-- +>[subseq from] Serine hydrolase n=1 Tax=Kocuria sp. HSID17590 TaxID=2419513 RepID=A0A433F856_9MICC +-------VTGILRDATGAVAVRVIDAPELPAF-GWRADEAFPAASLYKLVVMVAFCRAVD +RGELDPTALVTLRPEDRADPTGLAICQDPVRISWRDLVRLMMTVSDNAAGQAVLREV-GH +ARIRDVLREMGLSSTVVRPG-PAPDAGYDPLLVSATTASDLVALLCAIWQDRAASTAQCA +FMREVMSQQAWGHRFAEAFSYPGAGVAAKTGSFG-ALCHEAGVISHPGEKSIAVAVLTRS +VRRQIAVSNRIVGQIARHCVRSy +>[subseq from] serine hydrolase n=1 Tax=Micromonospora yangpuensis TaxID=683228 RepID=UPI000B88CE5A +-----------LDGLGGSVSAYLGRLDAPPTW-TRRADATHYAASTMKVAVLAALHRAAE +SGRLDLDAPVEVVNDFASADAPRFWARLGTGATLRWLAERMIVRSSNLATNILLDHV-GL +PAVARVWAAAGARHSVTGRGIEDFAA-RDAGIANLVTVADLAALLAAIATGALASPAHCA +AMRDVLLAQQH-RDDLAAGLPEGTPIAHKSGWVR-GVRHGAGVVYPDDAPPYVLVVCTTT +EGRD-VDACRLLADLSA------ +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis coloradensis TaxID=76021 RepID=A0A1R0KFB3_9PSEU +----IETINDRAEEVGVRVRLHAAEIDGIRRI-GVDEHAPVVTASVFKVPIALELARQAA +DGVLDLGERITIPPGHPTPPYGLATFRHGITMSWYDLAILMIGISDNVATDLILARV-GK +ESTEKTLRRLGFEHTTVPQDCGEVLGALRPAHTCATTAEEITRLLGLLWRDEAASPTACA +DVRRWMELQVW-PHRLRSGFPDGVRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora yangpuensis TaxID=683228 RepID=A0A1C6UYU9_9ACTN +-----------LDGLGGSVSAYLGRLDAPPTW-TRRADATHYAASTMKVAVLAALHRAAE +SGRLDLDAPVEVVNDFASADAPRFWARLGTGATLRWLAERMIVRSSNLATNILLDHV-GL +PAVARVWAAAGARHSVTGRGIEDFAA-RDAGIANLVTVADLAALLAAIATGALASPAHCA +AMRDVLLAQQH-RDDLAAGLPEGTPIAHKSGWVR-GVRHGAGVVYPDDAPPYVLVVCTTT +EGRD-VDACRLLADLSA------ +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora auratinigra TaxID=261654 RepID=A0A1A9A7T0_9ACTN +----AQRIAEIFGRVGVDGCLHVTDVDAPRREiAVRADEQIVIASVFKILLVLEFARQAV +AGQLDPTERVLVRAADRLGGWGVAGCADDVEISLRDLAYFTMSVSDNTAADLLLRRV-GP +DVPPMLAAELGLARTRIRGGPRELVEVFDPAHTTSSTARELTRLLELIWRDEAGPPAACA +MVRDLMARQLF-WTRLAAGFPPGVRVAGKTGNLP-GLHLEAGVAEYPDGGRYAVLVHART +RRLSRIDVDLAMGEAARVAV--- +>[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. N23 TaxID=1987376 RepID=A0A292YVQ5_9PSEU +---------------------------SEREI-DVGADVPVVMGSVYKVLVLVAFCRAVD +AGDLDPREQVTVEPGPRTPPTGISALTDPVTMSWRDLTRSMITVSDNAAADVVHARV-GR +DRVAALPTELGLPGTRVRGGTADAYALLSPAFGSSTTAADSTRLLTLLWRGELASAAGTA +FARRVLTAQVA-PHRMRTGFPGTAAVAGKTGTIG-AVRNEIGVVTYPGEHPVAVAVFTHA +ARATVPRADAAIGVAARAAVN-- +>[subseq from] Serine hydrolase n=1 Tax=Desulfobacteraceae bacterium TaxID=2049433 RepID=A0A3A4X3J6_9DELT +-eKLAGELNRMCDRQPFQTGWYLKNLRTGEAC-DRNGDVVVPSASTRKVSILMALLKEVN +EGRFRLDQPVVIEEKYQKNNSGTFQHLTPGFVTLQDAAYMMIIVSDNTCTGTIIDMV-GL +DAVNRLCRSVGMKGTFHRDTIPPFCADHSLEEVTTTTPADQGLLLDLILKGTGCTPELCR +LGIEILSRQKL-SWRLPALLPYGTKVAHKTGTGRAGNNNDVGIIFQGSRPLFILTVYTEH +VPLE------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Kribbella soli TaxID=1124743 RepID=A0A4Q7WU65_9ACTN +----NARIRAVFEDAGVRGWLHAVALDEPDLTvEVDADGIVPLASVYKLPLLAGFCRLVD +LGELDPRQQLTLDPSTKTGGPTGLSTFADPVASLRDLALSMMTLSDNASADALLDIV-RL +PRLAELLKSFGLQRTWVRRGTAGNLRVYEAVNASASSARDMTLLLRRLWAGELLSPEQTE +FAKATMHRQVF-MHRLASGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGTAYAIAVFTLA +ARGDQPRVDAAIGEAARVAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Auraticoccus sp. F435 TaxID=2656650 RepID=A0A6A9V2L6_9ACTN +---VADDIRQEWRRAGLSGGFLARHLDSSEQL-GFEVDRAVPLASVAKVPLALVAYDQIV +AGQLDPAQPVELRPEERTLGPTGLSLEHPCTVAVGDLITMALAVSDNAATDALMRFV-PP +AEVTRRMRQWGWHDITLRHHIHELNTQLDTSHANTGTAAALVRLLEAVWTDRVSVPAATA +RLRRTMAHQPS-HRRLGAELIDLTSVVGKTGTFLN-LRHEIGVVTTADGDRVAVAALTVS +SVGEQPEVDAAIGAAARVAVE-- +>[subseq from] Serine hydrolase n=1 Tax=Embleya hyalina TaxID=516124 RepID=A0A401Z6Z5_9ACTN +----RGRIGAAFADAGVTGALHAVDIDAGREV-EVGADTLYSTASLHKLCLVTTLFREAA +AGRVELTRRIELPAGPGRSGTGVAAMLDPVTMSLRDLASLTVAVSDNAAADALWDEL-GL +DTVNATMVDLGLTRTVAIEPLRELYAALDPNRSNRGTPRDLTRLLAAIWRDEACGGEYGA +GLRRVLGLQAW-SHRLASGFPDDVRVSGKTGTLPT-MRHEAGVVEYPDGGRYAITVCTRS +ADAALPAADAVIGTVGRLAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Parcubacteria bacterium TaxID=2053309 RepID=A0A3A4V0U8_9BACT +---VKQKVAEFISKEDLKFSVYYKDLVTGQTF-GIDENKVLTGASLNKLVIVAYLYNLAK +DNKINLEEKVVVQKEDIQDTGSIRYDEPGKVYSLKTLAKLSLEQSDNTAAHLLVLKL-GV +DEVEEYRKRLGLVATDME--------------NNKTSSRDMGKLLDLVYSRKITSEALTL +ELLDFMKDTDF-EDRIPRFIDGDVKIYHKTGDAV-GMIHDVAIVEGK--RKFILSVLTSE +VG-DEEKAKNVIGRLAKIIYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Clostridium fallax TaxID=1533 RepID=A0A1M4WUJ6_9CLOT +-----KEIKKYIETRNGKYSFFFEDLDGGYVY-GYNEHEPMTAAGCMKLPIAVALIKEEE +LGNINFLDKIKIETKDKVYGTGIIHEFGERDYTVFELLVAMLIQSDNTAANKIIEIL-GI +EKINETIKKLGLKNTNLNRKTRD-ERNPEVEIENITTAYDLCMIWKHLYNATYLDRKNST +MLIDILTRQQI-KNKLGLYIPSKYSISSKSGDKH-GVENDTELIHLSKGN-FTFTVMSEG +VPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Daviesbacteria bacterium RIFCSPLOWO2_02_FULL_36_8 TaxID=1797793 RepID=A0A1F5MGM7_9BACT +---LDKAVATALEGVKGNYGIFIKNFKTGETF-KQNEHMIFHAGSLYKIWIMAETYNQIK +TGDLTEDEQLSRDIEYLNKKFQIAEENAELTLTVANALTQMITISHNYAAMLLTEKI-KL +SSVAKFLKDNSFIESKVGI-----N-----GEDPTTTPADMEKFFEKLYKGEIIDQEYSN +KMLELLKAQKL-NNKLPKNLPTETIIAHKTGELGF-YTHDGGIVYSPKGD-YIIIVMSQS +DSP--PGAEERIVDISEAVYKYf +>[subseq from] serine hydrolase n=1 Tax=Paenarthrobacter nitroguajacolicus TaxID=211146 RepID=UPI000A70B34D +--HITDQIRAIFAEANVTGLLHVRALAPGSEI-SVGADRPVVLASVFKIPVALAFARAVQ +EGRVDPLERVILGSKYRVGGIGAGGCRQDLEMSLGDLAMFMLTLSDNAATDLILERV-GV +DAVNALLSELDLVETHVGGGCLALWELDPRRSLHRSTPRDITHLLSYIWAGRP-DTQANQ +MVRSIMEEQVW-THRLSSGFNDSVIVAGKTGTLPT-VRNEAGVVTLPDGSSYAVAVFLRS +QSDRQPKADAAIGHAAYLAID-- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridium saccharobutylicum TaxID=169679 RepID=A0A1S8NAL4_CLOSA +-----KEIKQYLESRIGTYSLFFEDLQGNYSY-GYNENVQMTGAGCIKLPIAVSVIKYVE +DGKASFLDKIKIEDSDKVYGTGILHEFNNREYTLFELLIAMLIQSDNTAANKFISIV-GK +DRINQDIVSQGLKNTKLNRKTSDESQ-EDNRTENITSALDLSKIWKHLYNASFLNRENST +MLIDILQRQQM-KNKLALYIPDDYEISSKTGDKSN-VENDTALIRTKKGA-YTFTVLSMG +VPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Beta-lactamase class A n=3 Tax=Candidatus Amesbacteria TaxID=1752730 RepID=A0A0G1V2M3_9BACT +------VLNEITATTSGEYGIYVLDPVSGSGY-GVNEEVELPAASIMKVPIMATVYKLVE +SGEMELNDTYTLKESDKRYGSGPLEFVKAGTLTIRRLLSEMGKKSDNTAPVVLTNLV-GT +EKVEDMIGKLGMKQTDFGK--------------NTMTAKDASAMWKTLYNGKILDDEHLK +MMWEDLKDSIY-EERLPAGLPEKLEIVHKVGTDAD-VWADSGIIMPQTTKPLIITILNEG +VK--RAEAEQMVPELTRRIWE-- +>[subseq from] Beta-lactamase class A n=2 Tax=Candidatus Amesbacteria TaxID=1752730 RepID=A0A0G1UVY9_9BACT +------VLNEITATTSGEYGIYVLDPVSGSGY-GVNEEVELPAASIMKVPIMATVYKLVE +SGEMELNDTYTLKESDKRYGSGPLEFVKAGTLTIRRLLSEMGKKSDNTAPVVLTNLV-GT +EKVEDMIGKLGMKQTDFGK--------------NTMTAKDASAMWKTLYNGKILDDEHLK +MMWEDLKDSIY-EERLPAGLPEKLEIVHKVGTDAD-VWADSGIIMPQTTKPLIITILNEG +VK--RAEAEQMVPELTRRIWE-- +>[subseq from] Peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 n=2 Tax=Granulicella TaxID=940557 RepID=G8P1Q7_GRAMM +--ALLAQLQPILAAHHGKVALYAVQLNNGKAV-GIDQNLPVQTASDIKLAILYEAMLEVR +EGKAHWDEKLVLKPGDPVPGSGVLTFFDTPLLTLKDALTMMVIVSDNTATNLMIDRF-GT +DTVNARMASLGLVNTHLYKKIMKPATDQPKFGLGKTTPYEMATLMTRIGRCELHAEA--- +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Woesebacteria bacterium RIFCSPHIGHO2_01_FULL_39_28 TaxID=1802496 RepID=A0A1F7YA19_9BACT +------EFKNITNKLSGLYGFYVVNLESGFSY-GVFQDEVMQAASLIKLPVFATLYQEAE +SGNINLETKYTLKNSDKLGGSGSLASKPEGTFTYRELARLMGKQSDNTAFNIFRKVL-GD +DKIDKVIEKIEMKNTSLA--------------ENLTSPADIGTYFGKLWNGKIVGSKSKD +EILSYLTDTIY-EDIIPKGVPEEVVVAHKFGRDLH-IINDAGIILTD--KPFVLVVMSQG +IIE--KEAEIALPQIVKTAYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora peucetia TaxID=47871 RepID=A0A1C6UC29_9ACTN +-----ERIAEIFERAGVTGCLHVVDLDGGSEV-AVRADEQVVIASIFKVLLVLEFARQVV +AGQLDARERVLVTADDRLGGWGVAGCADDAEVSLRDLAYFTMSVSDNTAADLLLRRV-GA +DVLPMLAAELGLPRTRVVGGPRQLVEMFDPAQTTSSTAREITRLLGLIWRDEAGPPEACV +MVRGWMAQQLF-WTRLASGFPPGVRVSGKTGSLP-GLHLEAGVAEYPDGGRYAIAVFVRA +AQTRRIDVDLAMGQAARTAV--- +>[subseq from] PEGA domain-containing protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535WM37_9CHLR +---------------GGQWGVYLEDLKSGEGF-GWGQDNLLEAASDIKIPVALYLLHQIE +AGGVQLTDEVTLQAADFMGGTGTLQGNPGDKYKYWDLLNLLIQVSDNTAWRALQRAL-GA +DAIDAYAASIGAPD---------CHQV-----DDNCTAHEAGLMLSQLDRGKLLNPGDTS +FLLTLLENTIY-NERIPYYLG-GITVAHKTGSDGS-VCNDVGIVLLNGH-PFILSMFTWT +DD--YTTGLQAIRDVARAAVDYf +>[subseq from] Serine hydrolase n=1 Tax=Oceanobacillus sp. E9 TaxID=1742575 RepID=A0A1E5K5T6_9BACI +---------------PVSVSVILKN-NTGI-I-CSKETKQMRSASIIKLFILASAYHFKE +IGKLSLTEKIRISTNGHVKGSGVISYLTDIPLTYQQLLELMIIVSDNTASNYLIDRL-GI +SNIQAFIESLGCQQTRLERKFMDVEAQ-KLGKENVTSALDVLRLFDIFTENNFLGENSQQ +HILHILNNQQF-NSKLTAFTEPLVTSYHKTGELK-GVEHDAAIFLQNNK--FLKVVVLTE +GWENNGDGQAFIASFGKVL---- +>[subseq from] serine hydrolase n=1 Tax=Clostridiaceae bacterium TaxID=1898204 RepID=UPI0011C8342B +-----KEIKRYLETREGEYSFYFADLKSDYTY-GFNENLKMVAAGCIKLPIAMAVMKEVE +ANNISLEQLVSITNDDKVSGSGIMHELEGRQYSIKELIVTMLIQSDNTAACKLINII-GK +ERVNCIVQDMGLKSTIINKYPSGERE--EFENENITTSYDLCKGLALLSRGKVLNKEHSK +FILEIIRRNQL-TTGLPFYWPKDAKTAHKAGSLE-GIENDIVLLSSEKGD-FVFVVMSRN +LPS-NVYGVS------------- +>[subseq from] hypothetical protein n=1 Tax=Streptomyces rubrogriseus TaxID=194673 RepID=UPI00131F3160 +------------------------------------------------------------ +---------------------------------------AAARQRHNTATNLPLDLLGGP +TAVTAFASGLDDATTRFDRNEPQLNSTGPDDERDTTTPAAIVESMRAVPLAGGLQPAGRE +RRTTSLVANTTGDATIRAGMPAGWLIGDRTGTEAQGERNDVGIVLPPDRAPLV------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00048438AE +-----------LDRMPGTVSAYLARLDAAPTW-TRRPDTTHYAASTMKVAVLVALHRALA +AGDLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLRWLAERMIVRSSNLATNLLLNQV-GL +PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPESCA +AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS +DRPDHSRDEDACQLLADLSA--- +>[subseq from] protein kinase n=1 Tax=Desulfosporosinus sp. FKA TaxID=1969834 RepID=UPI0011251003 +------------QDSKGSYFMYLRDNTTKEEYaNSEANDSKVAGGLVYIPIMTTVLIEHF +NGNLNLDKLITVQG--IAGTGKLTRQDSGRSLSIKQLLELMMRYSDNTAANLLIDELGGL +ERINKTMRSLNIDGIVLNRKLMDQQ-AMNRGLENYCSPRGIGSLLSLLAENRIMAAQDCE +YSISIMGNNDH--TGMAKYLPDNILISHQTGILT-GVFNDAGIINTPKGR-VVLVLM--G +EKVDQDTATEIFGKVARAVVEQ- +>[subseq from] Uncharacterized protein n=2 Tax=Halostagnicola larsenii TaxID=353800 RepID=W0JTB6_9EURY +---LATYLGSYTDRIDEKVGVFLGYPKTASEFyERRACERFASASVIKLVIQYALYADYD +GDLEKLRTVRSPSRENCVGGSGVLNLFDDPTVTLEDLARAMIAISDNTATNELIDVL-GW +GRINDSADTLGMSQTALQRKMMVGLERPDDRPVNVTSPRDCARFFADFVHRETLSCSAYD +RMKVPLRNQNF-TEMFPRYIPSEIELCHKTGFLPT-AALDTGVLFADN--PLVFSVFVDQ +TNRD-SDGADIIAEIGDAVYT-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3C0XQ01_9CHLR +-----TSLQPLVASFDGDATVWIARPDQAEPLfSVDPDRPVLAASLYKLAVMLEVERRVE +AGGWSYENPVVIRDEDVTIGS---NEFPGTVLTVDAALEEMITYSDNGSALALLRLV-GA +QRVNATLGAAGLGNFHVA-----LN----ADDDHTVTARAVGTFFALLGRGELLSPAASR +RMLERLQRQHI-NDRMPAKLPAGTVVAHKTGDLV-GYTHDGGIIQSSSG-PLIFVALTQD +APQD--DARQFIAQAAALAYH-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. HSS6-12 TaxID=2720024 RepID=UPI0014396C23 +---------AHLDRVPGTVSAYVARLDAPPTW-TRHADATHYAASTMKVAVLVALHRAAE +AGRVDLDAPVPVRNESALPGAPRFWARAGGSAPLRWLAERMITRSSNLATNLVIAHV-GL +PAVADVWARAGARHSVTGRGIEDFAA-RDAGITNLVTAADLAALLGGLARGTLAAPESCV +AMLDTLTAQEH-REDLAAGLPAGTRIAHKNGWVH-GVRHGAGVVHPDDAPPYVIAVCTTT +DLADEDDACRLIARISREVWN-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium HGW-Chloroflexi-9 TaxID=2013732 RepID=A0A2N2LIQ9_9CHLR +---------AATTNADVTAGVVLLDLASGERC-EVGATREFRTASLYKTVVLAELYRQID +GGLVALTDPLTLEPRHSVDDPPEFALTEAYRTTVGNAAQRMILYSDNASALALREQL-GI +NLVDTAPAWLGMTSTVLGTRF-------------VSTPRDQAELYRRIYAGEVVSANASR +AMFQVLAEQEI-SDLIPAALPSGVRVAHKTGALDT-YLHDAGIVRAPGGD-FVLVVMTEN +TD--FAGAQEVIHEVTAAAFEPf +>[subseq from] Serine hydrolase n=1 Tax=Saccharothrix sp. CB00851 TaxID=1835005 RepID=A0A1Q4WXB3_9PSEU +-----ARVRAAFTDAGVTGRLHAVDLDHDREV-SVGADDPVVLASVFKVPLLVALHHSTH +----DLTRRITLDHDRSTGPTGVGGMLDPVTMSLRDLAYLAVTVSDNAAADALMDLV-GT +DAVNRALRDLHLTRTAVVHRARDFMRALNPDHTNRGTARDLTTLLRHIWQHD-----DCA +PIRHAMARQVW-PHRLSSGFPDDVRVAGKTGTLPT-IRNEVGVVEYPDGGRYAVAVFTRS +ASFTLPQADAVIGTAARLAVEH- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E7D1K4_9PLAN +-qSLKQRISELEKRFDGEFSIEVKRLDKPGYF-ELRKDVVRPTASTCKLFVLCELLRRAE +NGEIDLNSEITWKPEFHRGGDGVLRAMVPGQLTIHNMAILMMMISDNIATATLVDLL-GG +ENITRTIRSWGLESSNIHDGLPGGA-NYSKMKQPVSTASDMLSLITKIYRHEVLTPKSCD +EIIRILRAQRC-NDMLPRYIPAKTWIANKTGYGA--CRVEVGIVKAQDVT-FSLAMFFK- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000485E9EB +-----------LDRMPGTVSAYLARLDAAPTW-TRRPDTTHYAASTMKVAVLVALHRALA +AGDLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLRWLAERMIVRSSNLATNLLLNQV-GL +PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPESCA +AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS +DRPDHSRDEDACQLLADLSA--- +>[subseq from] serine hydrolase n=1 Tax=Agromyces sp. MMS17-SY077 TaxID=2662446 RepID=UPI001328E68D +---SEREAAALLREAGLTASVLVRDLRDGREL-GIDADRAFPLASVVKLPLALAVLLDAD +AGILALDERIALDPASRTPPTGYCRFRHPTEAAVEDLLYQAMCVSDDTAADALFARC-PP +ERVTARMRELGIADVTVRHAISELHAQLDVTNANAGTARALVDLLELIW-GDRLSPTVAA +ELRGLLAENLL-RHRLAPDLEDDARWHSKTGTFLH-LRHEVGVLEHADGGRFAIAVLSES +SVYRQPGAEQALGAAARVLHD-- +>[subseq from] Serine hydrolase n=2 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3B9Z2N5_9CHLR +---------------PFKTGWSFHDLVTGETA-NRFGDLVVPAASTRKVAILMTAMQAVN +RGELSLEEPVTIDERWQISDSGVFQFRPGFTITMHDVLLMMIIVSDNACTGIVCDRL-GL +DAINRFSQSVGMTGTVHREGIPQYTLSDARGTVNETTPNDMARLLHVILRASGVTPALAE +LALEMLSRQRL-RARLPFLLPGDTRVAHKTGTSGT-TYNDVGIVYRGDMPRFILAVYTSD +VPAVLPDGRAAPGATSK------ +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00036C34AE +-----------LDRMPGTVSAYLARLDAAPTW-TRRPDTTHYAASTMKVAVLVALHRALA +AGHLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLRWLAERMIVRSSNLATNLLLNQV-GL +PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPESCA +AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS +DRPDHSRDEDACQLLADLSA--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=UPI0005268FF0 +-----------LARADADIQLHAVDLDTGGDV-AVAADQQVVIASVAKILIVLEFARQAA +SGQLDPGAHLTIRSEDRLGGWGIAGCADDVEISLRDCAYFAMSLSDNTAADAIVRRV-GG +DAVGMLVAELGLDRTRFLGGPRHLLRVFDPRRTTSSTARDMTRLLGLIWHDRAGPADACA +AVRRLMTRQLS-STRLASGFPPPVTVAAKSGTLP-GVHMEAGVVRYPDGHRYALAVFATA +RDARPADLDETIGRVAHAAVQ-- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. 15K316 TaxID=2530376 RepID=A0A4R4QLI9_9ACTN +------DLDAQLDTAPGTVSVYVGRPGAEPAW-TRRADATHYAASTMKVAVLAALHRAAE +AGTLDLDAPVPVVNADSAQGAPRFWARVGGTAPLRWLAHRMIVRSSNLATNLVIGHV-GL +PAVAEVWSLAGARHSVTGRGIEDFAA-RDNGITNLVTAADLAALLGALATGAIASPAACA +EMLDVLVAQEH-REDLAAGLPPGTRIAHKNGWVR-GIRHGAGVVFPDDAAPYAVVVCTTR +DAEDDADACALIADVSARVWA-- +>[subseq from] hypothetical protein n=1 Tax=Gulosibacter sp. Marseille-P7157 TaxID=2479839 RepID=UPI000F63F050 +-------------DYGCRWSVLVRDIDTGEELlSHRPDRVLSTASIGKVFLLHRLLREVD +EGTRSLDEVVARRPSELIGGSGIWQLLQQPTFSLYDLGAFIGAVSDNSATNTLARVV-GL +DAVTEHTRALGYEHSRLNDIIRWPIPPGMAPRLSEGNASELVDFVERVQRGDGLSPASSD +VLRGWFGAGMD-LSMVGSVFDNGVWFWNKTGTLTT-VRADIGMVMTPTQR-VAYAALAQW +DR-DEDARGPVLETMAE------ +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RBG_13_37_7 TaxID=1798369 RepID=A0A1F5YJS9_9BACT +----VDKLEGIISGKTGTYSIYYYDIKSGIST-GINEKMVITAASVNKIPILAALYYLAG +NNTLDLEKIIVPQPSDIQNGTGIRYDPTGTPYSIKTLARLMIEKSDNTAAYLLGTHIVGL +KKIQNLINDWGLTQTDMY--------------KNSSSVYDQSIILIKMYQKEITTPSLTA +EMLGFMDKTDF-DDRLPKGVPEGITIYHKTGDEV-GKVHDVGIIDLPQR-PYYLGVFTTD +IT-DIEDAKKNIALISSAVYD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=UPI0009821538 +-----------LARADADIQLHAVDLDTGGDV-AVAADQQVVIASVAKILIVLEFARQAA +SGQLDPGAHLTIRSEDRLGGWGIAGCADDVEISLRDCAYFAMSLSDNTAADAIVRRV-GG +DAVGMLVAELGLDRTRFLGGPRHLLRVFDPRRTTSSTARDMTRLLGLIWHDRAGPADACA +AVRRLMTRQLS-STRLASGFPPPVTVAAKSGTLP-GVHMEAGVVRYPDGHRYALAVFATA +RDARPADLDETIGRVAHAAVQ-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. 76 TaxID=2035220 RepID=UPI000C182F6F +-----------LARADADIQLHAVDLDTGGDV-AVAADQQVVIASVAKILIVLEFARQAA +SGQLDPGAHLTIRSEDRLGGWGIAGCADDVEISLRDCAYFAMSLSDNTAADAIVRRV-GG +DAVGMLVAELGLDRTRFLGGPRHLLRVFDPRRTTSSTARDMTRLLGLIWHDRAGPADACA +AVRRLMTRQLS-STRLASGFPPPVTVAAKSGTLP-GVHMEAGVVRYPDGHRYALAVFATA +RDARPADLDETIGRVAHAAVQ-- +>[subseq from] Serine hydrolase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=A0A1S1KXE9_MYCCH +-----------------------------PIV-DVDGDRPAVAASVYKIFVLIAAARAFD +SRRLDPEATVRVVPADCTPGPTGISTFSNPVLSWLDLARLMITHSDNTAADVLLAAI-GL +DTVNELTEELGFNSTRIIGGTSALQRAFDPAYTTATSACDTDRALSAIWTGTATSAQSSD +MMKQILTQQIW-QHRIRSAFPRDVTVAGKTGTIGP-IRNEVAVIAFPGEPPMAVSVFTRA +ARADLPNVDRAIGQAARIAI--- +>[subseq from] serine hydrolase n=1 Tax=Brevibacterium sp. 2SA TaxID=2502198 RepID=UPI0010F59328 +-----DEINGVWTSLGAQGFLYAEHLGTHRSL-GIRESARIPLASVGKVAVIAGLLDAAA +DGTVDLTQRLLVDPAHSTPGTGIAGLLDPVEMSVRDLAAMALSVSDNAAADTLFDLV-GP +DRIMAVLHRAGIRSFEVTSPMSHLYDLLPDSAFNTGTVRATAKLFELIHTGQLLGPEGSE +TLRRLLRKQIF-RHRIAAGFPDAVQYYGKTGTFLN-FRHEAGVVVDSDGSAYSIAVFTRS +SIATQPELDASIGYCARLAIEH- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ299 TaxID=2035244 RepID=A0A2G6XEZ1_9ACTN +------------------------------EI-GVRADDQVVIASIFKVLLVLEFARQVE +AGQLDPTERVLVTADDRLGGWGLAGCTDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP +DLLPMLAAELGLSRTRVLGGPRDLVEVFDPEHTTSSTAREITRLLTLIWRDEAGPPAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA +DRSRRIDVDLAMGEAARTAV--- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00037C91F3 +------------DRMPGTVSAYLARLDAVPTW-TRRPDTTHYAASTMKVAVLVALYRALA +AGRLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLHWLAERMIVRSSNLATNLLLNQV-GL +PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPESCA +AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS +DRPDRSADEDACQLLADLSA--- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Roizmanbacteria bacterium RIFCSPLOWO2_01_FULL_38_12 TaxID=1802061 RepID=A0A1F7IYX4_9BACT +---LEKNITEILNNKQGDYGIYFKDLKSEKTF-VLNADREFQTASLYKLWVMAETYRQIK +QGKLDKEHVMTAKIAELNEQFKIASKDMDDEYTVFDALNEMITISGNYSAFILGRQI-RL +FNVSDLLESYKLNHSSIGDNAIGIP---------TTTARDTGVFFELLYKGELIDEKSSI +AMLELLKKQQL-NDKIPRHLPEDIEIAHKTGELAP-FNHDAGIVYTDNGN-YIIAILSET +DD--QTHAEEVIANISKTVYDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Nocardiopsis sp. Huas11 TaxID=2183912 RepID=A0A495L6V3_9ACTN +-------------------RVHVREIGGPGEL-GHRADEPLALASVAKVLITLEFARQAA +TGALDPAERVVARREDRLGGAGMAGFADDVELSLRDCANLAMTISDNTAADLLEERV-GT +EPVHLLVRELGLEHTRFTGGPRALLRH-PPDPATSSTPRDLTRLLQLVWTDAAAPPRACA +FVRELMARQLV-RARLASGFAAEVLVSGKTGTLP-GLRLEAGVVEYPDGRRYAVAVAAVG +VQGDGHDVDAALGRAARAAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 76 TaxID=2035220 RepID=A0A2G6XX47_9ACTN +-----------LARADADIQLHAVDLDTGGDV-AVAADQQVVIASVAKILIVLEFARQAA +SGQLDPGAHLTIRSEDRLGGWGIAGCADDVEISLRDCAYFAMSLSDNTAADAIVRRV-GG +DAVGMLVAELGLDRTRFLGGPRHLLRVFDPRRTTSSTARDMTRLLGLIWHDRAGPADACA +AVRRLMTRQLS-STRLASGFPPPVTVAAKSGTLP-GVHMEAGVVRYPDGHRYALAVFATA +RDARPADLDETIGRVAHAAVQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Clostridium cadaveris TaxID=1529 RepID=A0A1I2JNR1_9CLOT +-----KEIKKYLESRDGEYSFFFEDLDCGYIY-GFNEDKLMPSAGCIKLPIAMALLKQCE +GCKLNLMDKVKIGPKDKVNGNGILHEFSDREYTIKELLIAMLIQSDNTATNKIISIL-SI +ENINETIKAMGLKNTKLNIVAMEEK-LHDGINENMTTALDLSICWKHLYKESFLNAENSE +LLLDILKRQQL-KNKLSYYFYSKTKVASKSGDLKN-IENDSILFEIPQGN-FTFTVLSDE +L---------------------- +>[subseq from] Beta-lactamase n=1 Tax=uncultured Clostridium sp. TaxID=59620 RepID=A0A1C6LE36_9CLOT +-----KEIKRYLESRIGTYGFFFEDLKSGFVY-GYNENVSMTAAGCMKLPIAVSLIKAVE +DGKVDFLDKVKIKSEDKVYGTGIIHEFNEREYTVFELLVIMLIQSDNTAANKIIDIL-GM +EKINQDILEMGLKNTKLNRKTTDERDN-HTNVENLTSAYDLNLIWKHLYNGTFLNKDNGQ +MLIDILRRQQI-KNKLALYLCDDYEISSKTGDKY-GVENDTEFIQVPKGD-FSFTVLSSG +LPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A521UR37_9CHLR +---LDNRIRQQLGTRITSYGVVVKRLADGRGT-VINPDQEFYAASVYKLFVMFEVFKQRE +LGLLSFDEVLTVTPPYQEFQIGDLRWPLWTEVSIRNLLEAMVTESDNVAAMMLYDKT-GG +RNMAQELTSIGLTHTDVNTD------------RLPTSAGDVAILLEMIARKQAINAAASQ +EMIDLLSRQKI-DGGLLTLLPKETKVAHKTGSWDN-ASHDVGVVYAPSGA-YVIAMLSDR +AGE-----LKPIAELSRLVYDYf +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. NRRL B-16802 TaxID=1415541 RepID=A0A0M8XIL9_9ACTN +------DLDAHLARVPGTVSAYVGRLDGPATW-TRHADASHYAASTMKVGVLAALYRAAE +AGSLELDAEVPVVNEDSAQGAPRFWDRLGGDASLRWLAERMIVRSSNLATNLVIAHV-GL +DAVAEVWSLAGARHSVTGRGIEDFAAR-GAGITNAVTAADLAALLGALATGRLASPASCA +AMLDVLLAQEH-REDLAAGLPEGTRIAHKSGWVR-GVRHGAGVVLPDDAPPYVIAVCTTT +DLADEDDACLLIAHISAQVW--- +>[subseq from] Uncharacterized protein n=1 Tax=candidate division WWE3 bacterium RIFOXYD1_FULL_39_9 TaxID=1802649 RepID=A0A1F4X608_9BACT +------KLKNSFAEQGNKFGFYIEDISTGKTY-AYNENVKIYAASMYKFPVAVTVLNEIQ +KKNMALTTELTYTQADFEGGTGSINRNSFGTFSIEQLLTNLIDYSDNVAQNILLHRI-SK +PQVGALINQ------NLDSTSGSLFAA-----ENVTSPAEMGNFLKNIYKGEQLTQENKN +LLFNEMAQTVF-DDRITMHLKEGLTFSHKIGSWDTGSWHDCGIVFGKQD-KFVVCVMSQN +TN--------------------- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0004229E42 +-----------LDRMPGTVSAYLARLDAAPTW-TRRPDTTHYAASTMKVAVLVALHRALA +AGHLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLRWLAERMIVRSSNLATNLLLNQV-GL +PAVADVWAQAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPESCA +AMLDILVAQEH-REDLAAGLPTGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS +DRPDHSRDEDACQLLADLSA--- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E7L426_9PLAN +--ELPQQIEQLEQKYVGTFSIKAHRLDADGHF-SLRPQTVLPTASTCKLFVLCELFRQAE +EGTIDLRAPISWKPEFYRGGDGVLRAMIPGQLSIHNMAVLMMIVSDNIATATLVDLV-GP +DNVNRTMKSWGFAATNIFDGLPGGPNA-AEMKQPVSTAHDLCTLMQRIYRHDVLTPESCD +EIIRIMRAQRC-NDMLPRYVPAKSWIANKTGYGA--CRVEVGVVKTAEV-TFSLAMFFRP +HQPPA------------------ +>[subseq from] Uncharacterized protein n=1 Tax=Kutzneria albida DSM 43870 TaxID=1449976 RepID=W5WCD3_9PSEU +---LAESIAEQWARAGVRGHLLARNLDTGEQF-GFDVDVAIPLASVVKVPLALAVLERVA +SGALDPARQITVDPATSSLSTGVSAFRYPATLAVGDLVHMMLTVSDNASSDVLLDLI-GI +DGLTGSLRAWGCADIHVRHRLHRMYETLDPAHANSASAAALVDLLHRVWLDRISEPAATA +ELRRLMSLQVF-THRLASDLRDTVRVSGKTGTFLH-LRHEIGVVEADSGDRVAIAALTRS +TRRAAQDIDLAIGSAARSAF--- +>[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2569 TaxID=2512220 RepID=A0A4Q7PXV5_9ACTN +----NARIRGIFEDAGVRGWLHAVSLDEPEASvELDADAVVPLASVYKLPLLAGFCRLVD +LGELDPRERVTLEPSARTAGPTGLSAFADPVVSLRDLALSMATVSDNASADALLDIV-GL +RRLAQILESFGLRRTWVRRGTAANLRVYEAANGSAASARDLTLLLRRLWAGELLSAEQTE +FVKTTMHRQIF-LHRLASGFPDGVRVAGKTGTFG-ALRHEAGVVTLPGGAAFAIAVLTLA +ARGDQPRVDAAIGEAARVAVD-- +>[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000379F64D +---------------------------GAAEV-AVDADEPVVIASVVKILLVLEFARQVA +AGQLDPRERVRITAADRLGGWGTAGCADDVELSLRDLAHFTMSVSDNTAADLLLARV-GL +DTVRLLTEELGLTGIRLVGGPRDVLEVLDPARTNAGPPREITRLLRLVWSDGAGPPQACA +WVRELMGRQVF-RHRMVSGFPDEVTVAAKTGTLP-GLHAEAGVVAHPDGGRYAVAVFART +REATRAAVDSAIGTATRISV--- +>[subseq from] serine hydrolase n=1 Tax=Deinococcus proteolyticus TaxID=55148 RepID=UPI0011D26DF2 +-------------------GLLIQDE-AGRDLcSLNAEAVFPAASLIKLPLLVLGLQAAQ +RGDVALVECLPLPAAEHVPGAGVLHELDAGLLTWRDLLTLMIVVSDNTATNMVIERL-GL +ERVQVALPGLGLTHTRLVGKLQQQNAAQRRGERNQTTPRDMLRLLQNLRQGEYLDASYTA +LALDILGRQQL-RDLMGRRVPCGYPVLSKSGELP-GVHHDAGWLLTP--RPLAVACLSLG +GEDP------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium RIFCSPHIGHO2_01_FULL_36_15 TaxID=1798586 RepID=A0A1F6HNS1_9BACT +-kALESIIQNILKNDKNYYGIVIDNLKTGERY-YFNEDKIFNSASLYKLWVMAVVYQKIE +NGRISKTNILSENVVDLNEISTESAELTQGTWPVQNALQLMITISDNYSALLLAEKI-GL +VSISDFLKKYGLSESKAGNLYKD----------PVTSAQDAANFIRQLYDGQLASSENTL +EMIDLLKNQQI-NTKLSKNLPKNTVIAHKTGELN-GFSHDAGIVYSQKGD-YIIVILSKT +DHP--LETNENIAEISREVYDYf +>[subseq from] Uncharacterized protein n=1 Tax=Streptomyces malaysiense TaxID=1428626 RepID=A0A1J4Q6Y6_9ACTN +-------ARAIFERAGCTGSLLVRPLDGSAEF-SVDADQLVVPASVVKVLVALAAETWFA +EGRLDPRERVVLGAAERTPPVGVSLFEDDAELSLRDMVVLMLTISDNPCTDMLVHRL-GL +DALNATAARLGLRNTVVRSDLRTMLDALTPGAGTSTTARDMVRLLRLVWSGQAGPEAACA +RVRAVMARQLT-RHRIASGFRAPVRVAAKSGGLAGIVRNEVGVVSCPDGRQYAAAVFTRS +RPADEAAVNAAIGAAARAV---- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00037CE890 +-----------LDRMPGTVSAYLARLDAAPTW-TRRPDTTHYAASTMKVAVLVALHRALA +AGHLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLRWLAERMIVRSSNLATNLLLNQV-GL +PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPESCA +AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS +DRPDDEDARQLLADLSARA---- +>[subseq from] serine hydrolase n=1 Tax=Kocuria rosea TaxID=1275 RepID=UPI00140BD29C +------------------------------------------------------------ +----------------------------GLGLTVEQALDVMISWSDNASGAALGQWL-GW +EQVEAFAHEQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSTA +LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG +WS-DYEESAPWFGDAGR------ +>[subseq from] Serine hydrolase n=1 Tax=Bifidobacterium callitrichos TaxID=762209 RepID=A0A5M9ZFQ0_9BIFI +------------------------------------------------------------ +-----------------------------DNATIDANLQQMITVSSNDAANRLLAVIGGK +GGTTAAIATVTDTAGRYGSSTKELRAASGNAVENWTSARDCGTFLSKAYRGELVSANASK +RMVDLLLGQTR-RTKIPAGVPAGVQVANKTGELA-AVQNDVAIVYG--ARPYVIAVMAND +VDES---AAANIATLSANVYQAf +>[subseq from] hypothetical protein n=1 Tax=Lactobacillus sp. CRM56-3 TaxID=2678357 RepID=UPI0012D3B59E +---------------KWTVAVTSLDGDQHAYMtNWSPGHAQSSASTIKLFILIRYYQELK +QGTIHASDRYTLRKADKVEGSGILHKKVGTQYTMSQLVKLMIEKSDNIATNVLINKLGSF +KGVDQTISQVGPHYSSLERKMMDISD-PDNGRSNRINAWEAVQTLRAIYRGHLIDASADQ +AMMTPMLKTEN-RTKLPANLPSGAICWNKSGESNRGVENDMGIIKYQGH-VFMIAALIEM +DGATEEQTESQVAAIAR------ +>[subseq from] Serine hydrolase n=1 Tax=Acidiferrobacteraceae bacterium TaxID=2024893 RepID=A0A2E9RCV6_9GAMM +--ALENELNQLCDEQPFHTGWSVKNLRTGTVL-ERHGSVVVPSASTRKIAIMMAALKAVN +EGELSLSQPVTMASRFKNNDSGCFQHLQSDFIQLQDALVMMIIVSDNTCTGAVADLV-GL +EAINALCQSIGMADTVHRYGIPGMAGYLPAEKTNSTTPADVAXLLELILKGVGCTSELCQ +LAIDILSWQRL-RNRIPARXPLGTKVAHKTGTTAK-NYNDAGIVYADGVPLFLISAYTDS +VPVE------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Dehalococcoidia bacterium TaxID=2026734 RepID=A0A315X4X3_9CHLR +--ALADAILGALARHPERASVAVVNLDDGRWA-AYDADRVQYAASTFKLAVLYEVERRVS +AGELTYDDRVLLDEEAVGEDLGTLERVPEDGVSVGEALDAMVTLSDNATAVALLRHV-GP +SAVDETLRAIGLTTMSVNTKELP------------ATAADLALLMRAIVTGEGVGDAQRE +HMRDLLLGQTI-RSGIPAALVTGLAVGNKTGTWPD-ITNDVAFVESDAGT-YVIAVTAEG +DW-----NWALVSDVSRAVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora ureilytica TaxID=709868 RepID=A0A3N9XRH5_9ACTN +-----------------------------REV-GVRADEQVVIASIFKILLVLEFARQVE +AGQLDPTERVVVTAADRLGGWGLAGCTDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP +DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPATACA +MVRTWMAQQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA +EQPRRIDVDLAMGEAARTAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium RIFCSPHIGHO2_01_FULL_37_17 TaxID=1798588 RepID=A0A1F6GWE9_9BACT +-qQLTAIVAESVKGKNGTYAVAVLNLKTGEEY-YLNKHRVFDSASLYKLWIMGYAYKKIE +NGLLDKNLLISDSIENLNRASESAEKNIGGILTVKNALDQMISRSDNYSALLLSSKL-GL +SNVKIYLNEYGLSNSNIGTK----------DSNPTTTVYDTFQFLYKLYYGELANQEYTD +EMLSILKKQVI-NQKLPKYLPDSLDISHKTGELGK-FSHDAGIVYANNG-PYIIVVLSET +NSK--NNADETIANISQEVYNYf +>[subseq from] serine hydrolase n=1 Tax=Actinoplanes sp. LAM7112 TaxID=2486853 RepID=UPI000FDABD6E +--------------------LHAVDIDTGRSV-GVGSDDQVVIASLFKILVVLEFARQVV +AGQLDPRDREVVRAPDRLGGWGTAGCADDVEVSLRDLAYFAMSVTDNTAADLLLRRV-GP +DVVPMLAAELGLSRTRVVDGPRQVLEVFDPAQTTSSTPREITRLLSLIWRDEAGPAAACA +MVRELMARQIF-WTRLPSGFPADVRVTTKTGTLP-GLHIDAGMVEYPDGGRYAVAVFART +RRARRIDVDLAIGEAARSAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Anaerobacillus macyae TaxID=157733 RepID=A0A0J6CZH7_9BACI +---VSERILDCFRTLEGNQSLYVFAP--DGEI-ALNEDQPVSSASIIKLAIMITALKKVD +NRELSLDSIIPIELSNKVEGAGVISFLSNDLWTLSDLIKLMIVSSDNTATNQLIELL-GE +AEINHTMKCAGAYHSKLMRKMMDRE-AFKDGRDNMISGKDTYLLLNELVTTHLLSESLME +WGTTVLMQQQL-KDKFPAKIAQNNVLAHKTGELP-GVEHDSGILFTSKG-PVIYAFLTAG +LI-ENRYGRDAISNAGRLLYDYy +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Shapirobacteria bacterium CG11_big_fil_rev_8_21_14_0_20_40_12 TaxID=1974889 RepID=A0A2H0KFF1_9BACT +----KKSIESILLPLRGKYGIFYEDIGSKNSF-GINEKEVFTAASLIKMPVLITLYREAE +IGNINLDEVYKLQASDKREGAGALQNKPGFEISYRKIAELMGKQSDNMAFNVVANKL-GT +EKIQNTINALGMKNTSYA--------------ENLTSPVEMGLLFRKLYLEKIISDKNRD +EILSFITDTIW-EDRIPVGVPEGINVSHKIGTEV-GVISDAGIVFGP--KPFILVIMSQE +VNE--IEARKALPEITKKIYE-- +>[subseq from] Uncharacterized protein n=1 Tax=Lentisphaerae bacterium RIFOXYA12_FULL_48_11 TaxID=1798578 RepID=A0A1G0ZTU9_9BACT +---------TVTSNVHGHFSVYIEDLKTGMWW-GLDEKESYNAWSLLKVSTLVALLKKAE +REQISLDEGIVLTPEELKYESPYIEKVTGSFMSIKELAERMIEGSDDAAAMALCKKL-SF +DEFQECFRAMAMPLATPPNILPR------------VSPEQYANLLRSLYRADYLDKTSCD +VALSLMSSTVF-SDQLRAGIPGEIQFAHKVGFNGTGDSHDCGIVFLSNR-PYVICVMSTG +TTK--EEADRVMSSLSRAVYE-- +>[subseq from] Serine hydrolase n=2 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6WDM7_9BACT +--ELVERLDALCDAVPFHASWYLKDVATGARA-DRHGDVPVPSASTRKVSIMMAALAAVH +AGKLALDQRLTVEARYQNNDSGTFQHLTPGFVTLRDAIVMMIIVSDNTCTGMVTDLV-GL +PNVQRWCETVGMTATIHRYGIPKMAPDHPLDQVTTTTPNDQGLLLELILKGTGSTPDLCR +LGLDILSWQKL-KTRLPSLLPLGTKVAHKTGTGAR-GYMDAGILFKDDRPLCILTAYTDR +VPAALPDGTPGFAAAAQLI---- +>[subseq from] hypothetical protein n=1 Tax=Caulobacter sp. CCH9-E1 TaxID=1768768 RepID=UPI00082AFFC4 +-----------ARAAPALLGVAAEDLGTRQIW-AFNGDQAFALGAAARVPILAAVMAERE +AGRLDPNETIQVRDVDLSPPSAIADAWPGRAYAVTEL-EALARAGDNTALDLLAKRIGGP +GAVNGWLGVKQLGGISVDLYRRQAETRRVADPRDTTTPVGMVRLLEAFNTREVFASADPR +PLLG----ND--PGYLAAALPKDAKIWQAAGSARRDESHAVALIELKDGRRVALAVFLSG +STADAATREALVAEAGRTVLKSf +>[subseq from] Uncharacterized protein n=2 Tax=Bacteria TaxID=2 RepID=K2DNU6_9BACT +--KVETQFAELAKKLPGVYGLYIKDVGSGREF-KYNDATEFYAASLYKVPIGAAVLKEVE +AGKLKLDDTATYLPYDYSSGTGVIGTYSHGILKISDILSELLKNSDNTAQNILLRTL-SY +KNVQETFNEI-----VPDKNTSTYY------RYNLSTPAEIGYVFEKLYFGNYLNDANKK +YLSDLMTNTSF-EDRVSAYLKDGLTFSHKIGSWPD-SWHDCGVVYTDNESELIVCLMSQR +AP--------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Microgenomates bacterium TaxID=2093373 RepID=A0A3A0BFX4_9BACT +-------------KRGVVVAIQMEYLNTGSYL-SINQNYRMLPASLTKVPVAMMVMRRIE +QGTLSFDQILELKDEDRDSWGEMYKLPVGTKMSLREVIEKSLTLSDNTAHKMLYRLV-GV +QEAQDMSQELNLEDL---------F-----DKEGKISAREYARLLRSLYSSSYLKAEYSQ +QLLDLMTRDQV-VKFLIRGLGPDVKYAHKFGESSY-SYLDAGIVYVPNR-PYVLVVMVHD +EASRELAGEQIFEKVAKLTYEY- +>[subseq from] CfxA2-like beta-lactamase (Fragment) n=1 Tax=human gut metagenome TaxID=408170 RepID=K1U1B8_9ZZZZ +---------KVIKDKKAEIGIAVI-LDAQDTV-TVNNDDRYPLMSVFKFHQALAVADYLN +RNGLTPDTEIFIPEEELVPYSPLRDEFPEGELSVSRLLEYSLQLSDNNACDILFEHTGGP +AATDRYVRSLGLCNFAIAATEQQMHDDPQTCYENWSTPLEAAALLELLVTEQ-------- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536D0A7_9CHLR +--DLASALDQAAAGVPGMVSVVVVDLDSGYVY-ERRADERVEAASLFKLFVMAALYRRAL +DDPQLFEATVPVSRPRLTAGQV---DYVLEPVAVREALEEMIDWSDNEATAALVELL-GT +DEVNATIASLGLRDSVVRSGEASGN---------STSARDIGRFLTLLARREIVSPEASD +AMTWLLLRQGI-NDRLSLGMPKDALFAHKTGNSA-GTFHDAGIAWTAWGE-RVLVVLTDG +VA--APDARALMKDLGYW----- +>[subseq from] serine hydrolase n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=UPI0013625D91 +------------------------------------------------------------ +--------------------------------SIESLINSMITVSSNDAFNTLFYKYLGK +GTVNKFCKANGYKKTQQYRPCGVGDES--GPKGNKTSAADCGMLLEKIYRGKMVSRAASQ +KMLNYLKRQTI-RTKIPRGVPYGIQVANKTGEDGT-IQNDVAIVYGKKT-TYIICVFSNT +NNPG--RAYNCIAEISRMVYN-- +>[subseq from] Beta-lactamase n=2 Tax=Granulicella sibirica TaxID=2479048 RepID=A0A4Q0SZR8_9BACT +-qELRGTLTAVAETHHGKVALFASQLNTGKTV-AIDADVPVQTASVIKLTILFEAMEEIR +AGKAKWDEKITMPAGYAVGGSGILTFFDAPMLTLKDVLTMMIIVSDNTATDLAIDRF-GV +DAVNARITWIGLKDTHLYKRIGKMPEDQPKFGLGKTTAREMARVMERIGRCQLAGPGEAA +LVAMNMLRNQFYRETIPRYLEKGSGIASKTGSLD-AVRADVAIVAGKTG-PIVISIFTYG +NTDHDNEGEVTIAKLAKLIVTAw +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora eburnea TaxID=227316 RepID=A0A1C6V512_9ACTN +-------LDARLDRVPGTISVYVGRLGARPTW-TRRADATHYAASTMKAAVLVALYRAAE +AGRLDLDDPVPVRNGSALAGAPRFWARVGGNAPLRWLAERMIIRSSNLATNIVIDHV-GL +PAVAEAWTLAGARHSVTGRGIEDSAA-RESGIDNLVTAADLAALLGELALGALASPAGCA +SMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWIR-GIRHGAGVVFPADAPPYTIVVCTTT +DLADTDDACRLIADISAQVWA-- +>[subseq from] Serine hydrolase n=1 Tax=Plantactinospora sp. BB1 TaxID=2071627 RepID=A0A2R4FGA7_9ACTN +------AITGIFDEVGVDARLHVTDIDGGAEL-GVGADDQVVLASIFKILLVLEFARQAA +AGQLDPTERVVVRAEDRLGGWGTAGCADDVEVSLRDLAYFAMTVTDNSAADLLLRRV-GP +DVLPLLAAELGLTRTRILGGPRQLLEVHDPERTTSSTARDVTRLLGLIWRDEAGPAPAGA +LVRELMGRQLF-WTRIASGFPPGVRVAAKTGTLP-GLHAEAGVAEYPDGGRYAIAVFART +RRTRRIDVDLAIGEAARTAVE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. A202 TaxID=2572899 RepID=A0A542EZ80_9ACTN +------------------------------EI-GLRADDQVVIASIFKVLLVLEFARQVE +AGQLDPTERVLVTADDRLGGWGLAGCTDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP +DLLPMLAAELGLSRTRVLGGPRDLVEVFDPEHTTSSTAREITRLLTLIWRDEAGPPAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA +DRSRRIDVDLAMGEAARTAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Tsukamurella pulmonis TaxID=47312 RepID=A0A1H1B7V5_9ACTN +-------IDGVFADAGCNGWLHARVIGHPAAL-SVGGEQPVVPASVYKVVLLVAAARAID +AGRLDPRARVSVDPACATPPTGIAALTDPVEMSVRDLLRSMIAVSDNAAAGELMRLV-GL +DAVQESARTLGLSGTRIVGGDAEIHAAYDPSFGSATTAADMTALLAAIWTDTAASPAQCA +FARSALGGQVF-RHRVASGFGSAPSIAGKTGTLG-ALRNEVSVVTYPGEHPVAVAVFTHA +ARNDLPRVDAAIGTVAAIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Aureimonas sp. AU40 TaxID=1637747 RepID=UPI000783E1C2 +-----------GDETCGRLSLFAKDLSTGRTI-EADADRVMGTASCIKLFILIELLRRVS +AGDLALGDRIAVHARQQVGGSGILKALSAGLMTLRDAAVLMMALSDNTATNMLIDLL-GL +ERINRTATELGCAHTRLINRIDFK--AIGGDITAVGTTRDFALALERIASGTLFYETASA +AALDILSCQLH-VDLLPRYLSQDLWVANKTGFFP-GFRGDVAIFTLPDRR-IVAAAFLDD +IE--------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Actinobacteria bacterium TaxID=1883427 RepID=A0A3D3Q7E7_9ACTN +--SLAVAIDAITAPTGTEIGVSLIELGAASSW-EVGGSQPMDAASTYKLPALMELAQLVA +AGKVDPAGQVCYQDADWED--GWFDDYTTGAYTRAELADRTAHYSDNTAGHMLVRDLGGG +DALNTYAAGLGAQNSAFF----D---------VNQTTADDLARLLAAEATGNAGGAQAQA +WLYPLLTNTEF-EAGIPAGVPAGTTVIHKTGELD-AQVNDAAIVTNGKNGTYVLAVMTNG +PGGD--AGSSLVAQVSAAVWAY- +>[subseq from] Beta-lactamase n=1 Tax=Moorella thermoacetica TaxID=1525 RepID=A0A1J5NHW0_MOOTH +-tKLQQQIQNYLADKPGTYGIYFKDLATGQSF-GINADTPLPAASTVKLPAVLFINSLVD +RGILDWQQKLTYNSADYQGGSGILQFSVKDGFTLRTLTTLAITVSDNIAYNMLRNFV-GQ +GSIASYMQSLGGRTVFP-------------SGQNLSTARDMATYIQAALDSAN-TSANGR +RLLDDMANGIY-NEGIPLQIPAGVTVAHKEGFVW-GSPGDVGVVFG--SRPFIVTVLSQG +VA-DPDQGFATVATVTRMMYDY- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Phormidesmis priestleyi TaxID=268141 RepID=A0A2W4X0Q2_9CYAN +----KAKLQGLPNTYGLSATVFYADVDTGDYV-DLSGGSAIAAASTIKLPILLAFFEEVD +AGRIDLNQAVAMLPEQIAEGSGDMQTQPGTQYTALEVVTQMIINSDNTATNMMIDLLGGA +EALNARFLGYGLEKTKINVPLPDLTGN------NTTSAKDLAHTLLLISQGNTLTMRSRD +RVLNILNRTYS-KDLLAAGMAQGALTYNKTG----------------------------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000480A7DF +-----------LDRMPGTVSAYLARLDAAPTW-TRRPDTTHYAASTMKVAVLVALHRALA +AGHLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLRWLAERMIVRSSNLATNLLLNQV-GL +PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPESCA +AMLDILVAQEH-REDLAAGLPTGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS +DRPDHSRDEDACQLLADLSA--- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium RIFCSPHIGHO2_02_FULL_40_18 TaxID=1798605 RepID=A0A1F6IUA7_9BACT +------VLEKFLKEEKGSYSIYYKDLSTGQEF-GINENKVLTAGSLNKLLIISYLYNLAS +DNKINLEDKITIQKKDIQDYGTGSLRYTGVGYTLKTLTQLALEQSDNTAAYVLSIRL-GE +DKIQEYGKKLGLTSTNMSN--------------NKTSAYDMGKILELIYSKKITSDSLTA +ELLDFMRDTDF-EDRLVRDIPSSVAIYHKAADSTN-MVHDVGIINDEKS-PFILAVLTSD +IK-DEEEAKKTIGKIAKFIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora musae TaxID=1894970 RepID=A0A3A9YKW2_9ACTN +-------LDAHLDTVPGTVSAYVGRPDAEPAW-TRRADATHYAASTMKAAVLAALHRAAE +AGALDLDAPVPVVNSDSAQGAPRFWARVGGTAPLRWLAHRMIVRSSNLATNLVIGHV-GL +PAVAEVWSLAGARHSVTGRGIEDFAA-RDNGITNLVTAADLAALLGALATGAIASPAACA +EMLDVLVAQEH-REDLAAGLPPGTRIAHKNGWVR-GVRHGAGVVFPDDAAPYAVVVCTTR +DAEDDADACALIADVSARVWS-- +>[subseq from] serine hydrolase n=1 Tax=Nocardiopsis trehalosi TaxID=109329 RepID=UPI0012F7AEE5 +---------------------------AGREV-AVRADERVVIASLAKILIALEFARQAA +AGQLDPTERVVATAADRLGGWGVAGYADDVEMSLRDCALSMMSVSDNTAADLVLRRI-GL +DTVQLLAEELGLVETRVIGGPRHLLEVFDPEHTSSSTARDITRLLALIWRDAAGPPEACA +AVRALMARQMS-WTRLAAAFPPGVRVAAKTGTLP-GLHIEAGVAEYPDGGRYAIAVFAAT +RSLDAR----------------- +>[subseq from] serine hydrolase n=1 Tax=Terrilactibacillus sp. BCM23-1 TaxID=2599694 RepID=UPI0012BD341A +-----EKLDQLVSPFGNKVSVVIQ--GDQCHY-TFNETTKMLSASLIKLPILLYAFEQIK +KGNLSFSQKIRISSDNIVDGCGIIQVLHDVNWSIRDLLGLMINVSDNTATNVLMDVL-GI +EHIQAWINDHQLNGTSIQRKMMDMEAK-KEGKDNFTCAADITHCMELIFSSSNSLSHDFP +FIDNYFLNQQF-RGKLPGKIETPVKIYNKTGEMER-ISHDTAFIKLKDKR-AIVTCMTSG +FD-DSIEADQLIQKIGERVYLF- +>[subseq from] Serine hydrolase n=3 Tax=Clostridiales TaxID=186802 RepID=A0A3A9J428_9FIRM +------------------------------------------------------------ +--------------------------------SIESLINSMITVSSNDAFNTLFYKYLGK +GTVNKFCKANGYKKTQQYRPCGVGDES--GPKGNKTSAADCGMLLEKIYRGKMVSRAASQ +KMLNYLKRQTI-RTKIPRGVPYGIQVANKTGEDGT-IQNDVAIVYGKKT-TYIICVFSNT +NNPG--RAYNCIAEISRMVYN-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora avicenniae TaxID=1198245 RepID=UPI0009713EFB +--------EGIFSRAGVTGNLHVVDLDTGPEV-AVGADEQVVIASIFKILLVLEFARQVT +DGQLDPTERVLVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLGRTRILGGPRQLVEVFDPERTTSSTARDITRLLGLIWRDEAGPAAACA +MVRGWMARQLF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFART +AQTRRIDVDLAMGEAARTAV--- +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Gottesmanbacteria bacterium GW2011_GWC2_39_8 TaxID=1618450 RepID=A0A0G0Q2B5_9BACT +------VIEEALEGTKGKYGVVIKNFQTGEEY-YANEHRKYEPASLYKLWIMATTFKQIQ +KGVLKLSEDIPVLNSKFHIDPTLAEQKEGKIMTVKDALEKMITISDNYSALLLSEKL-RL +SNVSDFLKENNFTESRLGE--PP-----------ISTPYDFAFFFEKLYNGELANEENTQ +KMLKILEKQTF-NGKIPKYLPDNVTIAHKTGEIGF-FTHDAGIVFSDKGN-YVIVVMSES +DSP--FGAEERISNISKAVYEYf +>[subseq from] Uncharacterized protein n=1 Tax=Kocuria sp. SM24M-10 TaxID=1660349 RepID=A0A0J1BU24_9MICC +--RLQADLQVLAAQVPGELGLVLLDPAGAEVV-SRNPDRPFTSASLYKLFLAHAVLDRVD +RGQIALTDTV-----------------PGTAFTVREAVERMITWSDNVSGAALGRWL-GW +HEVQAFAQGQGFESTTYDPDTGEAG-----TVAMTTTPDDVADFLDRLRTGDLLAEASTT +LLLGFLTAQEL-DYALSTGLSPDVEFAHKTGLLIQ-VSHDAGLVRLNGK-EYVVAVLTDG +WSG-------------------- +>[subseq from] Beta-lactamase n=1 Tax=Candidatus Daviesbacteria bacterium GW2011_GWC2_40_12 TaxID=1618431 RepID=A0A0G0T495_9BACT +--NLKNAVENVLAGTKGTYAVAIKNLKTGESY-FANEHKSFEAGSLYKLWVMAAVLSKIR +DGTLSEEQVLSRDISALNEDSEVAELTEGKILSVNDALTQMITISHNYAALLLTEKI-KL +STVANLLKEKGFGESKVGRGDD----------VPHTTPYDIFLYFEKLYKGELAQPEDTE +KMLVLLKNQKL-NGKLPKNLPKDTVIAHKTGEIGW-FTHDAGIIYSDKGD-YIIVAMSET +DKP--AAAEERIARISESVYRYf +>[subseq from] Serine hydrolase n=1 Tax=Goodfellowiella sp. AN110305 TaxID=1892852 RepID=A0A5B2XDZ2_9PSEU +-------IVGRADEVGVRVWLHATELDGPGRV-GIDATEPVVTASVFKVPVALELARQAA +DGELDLAERVTVAPGHPTAPYGLATFRHDVTMSWHDLAVLMIGISDNVATDLILARV-GK +DAVAESLRRLGLPGTAVPQDCGELLRALHPEHTCRTTAEEITRLLGLIWRDEAAPPAACA +DVRRWLELQVW-PHRLRSGFPDEIRVSGKTGTLPL-LRNEVGVVEYPDGGRYAVGVFTRA +VDSRVPERDAFIGFAAA------ +>[subseq from] Beta-lactamase n=1 Tax=Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399) TaxID=479435 RepID=D2Q356_KRIFD +---------------QGDFGVWLGRLDGVPVF-MHAAERPHYSASTMKVLVAMAMLRKVD +AGELSLEQPVTVHNDFASAEAPATWTKLGEQVTLGWLATEMITRSSNLATNLVLEQA-GV +DTAQAVLAEYGSGASAIQRGIDDVAAQ-AAGISNLMSPADLAAVLVAAGNDD---SASGR +YLRDLLAANEW-NGEIPAGVPAGTRVEHKNGWDVR-IRHDGGIVRPADAEPFVLTVCTTS +ELP-DPDAQKLIAAIAAEAWNH- +>[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis lurida NRRL 2430 TaxID=1460371 RepID=A0A2P2FKP2_9PSEU +--EVSETINERAKEAGVRVRLHAAEIDGTRRF-GVDEHAPVVTASVFKVPIALELAKQGA +EGGLDLGERITVPPGHPTPPYGLATFRHEISMSWYDLAILMIGISDNVATDLILDRV-GK +ESTEKTLRGLGFEHTTVPQDCGETLGALQPEHSCATTAEEITRLLGMIWRDEAASPTACA +DVRRWLELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEAGVVEYPDGGRYAVGVFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora avicenniae TaxID=1198245 RepID=A0A1N6XT66_9ACTN +-------VEGIFSRAGVTGNLHVVDLDTGPEV-AVGADEQVVIASIFKILLVLEFARQVT +DGQLDPTERVLVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP +DLLPMLAAELGLGRTRILGGPRQLVEVFDPERTTSSTARDITRLLGLIWRDEAGPAAACA +MVRGWMARQLF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFART +AQTRRIDVDLAMGEAARTAV--- +>[subseq from] serine hydrolase n=1 Tax=Terracidiphilus gabretensis TaxID=1577687 RepID=UPI00071B9173 +--SLDATLQSIAAAHHGKVALYAENLRTHQVA-SITPDLPVQTASTIKLAILLDAAEQIR +AGKASFDEKLVLSHENQVPGSGIIGQLDTPLLTLRDVLHLMVTLSDNTATNMAIDRL-GL +DHINQTILAAGLHQTWLYKKVYKPASDQPKFGLGKTTPREMAEIMTRLVTCNLAPLATQE +TFHVVMPDSASIDGPIRDGLPQGTAIGNKTGALDR-VRADVAIIASKSG-PIVIAAYTFE +NQDQDNEGKITLAKIGEAIVKAw +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ295 TaxID=2512146 RepID=A0A4Q8A751_9ACTN +-------LDARLDRVPGTVSAYVGRLDAAPTW-TRHPDATHYAASTMKVAVLVALHRAAE +AGRLDLDGQVPVRNESALPGAPRFWDRVGGSAPLRWLAQRMIVRSSNLATNLVIGHV-GR +PALADVWARAGARHSVTGRGIEDFAA-RDAGITNLVTAADLAALLGALAFGALATPPSCA +AMLDTLAAQEH-REDLAAGLPDGTRVAHKNGWVR-GVRHGAGVVYPDDAPPYVIAVCTTT +DLADDDDACHLIADISRAAWT-- +>[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Candidatus Woesebacteria bacterium GW2011_GWB1_43_14 TaxID=1618578 RepID=A0A0G1DMM8_9BACT +---IESRLEGMVSGLSGVYGVYIVRLDSGESY-GLMKDEIFQAASLIKLPAIAGIYMEAD +QGNINLNDEVAILEEDRVGGSGSLVGAPAGSYSYRELVNYMGNQSDNTAFRMVRRTL-GD +EKINDVIVSLGMTHTSLENN--------------ETTPEDIANFFTLLFEGKITSSRRAK +EIVDALTNTSY-EEWIPAGIT-GYSVAHKYGREVH-VVNDAGIVFSD--EPFVLVIMSKG +VVE--TEADKIIPELAKEVFEY- +>[subseq from] Serine hydrolase n=3 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536PK95_9CHLR +--DLASALDQAAAGVPGMVSVVVVDLDSGYVY-ERRADERVEAASLFKLFVMAALYRRAL +DDPQLFEATVPVSRPRLTAGQV---DYALEPVAVREGLEAMIDWSDNEATAALVELL-GT +DEVNATIASLGLRDSVVRSGEASGN---------STSARDIGRFLTLLARREIVSPEASD +AMTWLLLRQGI-NDRLSLGMPKDALFAHKTGNSA-GTFHDAGIAWTAWGE-RVLVVLTDG +VA--APDARALMKDLGYW----- +>[subseq from] Beta-lactamase class A n=2 Tax=Kribbella sp. VKM Ac-2571 TaxID=2512222 RepID=A0A4R6KY26_9ACTN +----NARIRGIFEDAGVRGWMHAISLDDPQASvELDADVVVPLASVYKLPLLAGFCRLVD +LGELDPRERVTLEPSARTAGPTGLSAFADPVVSLRDLALSMATVSDNASADALLDIV-GL +RRLAEILESFGLRRTWVRRGTAGNLRVYEAANGSAASARDLTLLLRRLWAGELLSASQTE +FVKTTMHRQVF-LHRLASGFPDGVRVAGKTGTFG-ALRHEAGVVTLPGGAAFAIAVLTLA +ARGDQPRVDAAIGEAARVAVD-- +>[subseq from] Beta-lactamase related protein n=1 Tax=Amycolatopsis azurea DSM 43854 TaxID=1238180 RepID=M2NS50_9PSEU +--EVAETINTRAKEAGVRVRLHAAEIDGTRRI-GIDEHAPVVTASVFKVPIALELARQGA +DGELDLGEPVTVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILARV-GK +EPTEKSLRRLGFEHTTVPQDCGEVLDALQPAHTCATTAEEITRLLGLIWRDEAASPAACA +DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] serine hydrolase n=1 Tax=Agromyces sp. KACC 19306 TaxID=2592652 RepID=UPI00143D1344 +------EAARVLDDAGLTASILVRDLATGREL-AHRADAPYPLASIVKLPLALAVLRAAE +TGDLDLAEPVRLDPGRRTPPTGTCRFEYAAEIAIGDLLSLAMCVSDDTAADALFDRC-SP +DAVTAVLREVGVEGITVRHRIRDLHEQLDVTGANAGTARALVDLLERIWGDPALA-RERE +PLRRLLSGNLVRQRLAPDLESDDAEWFSKTGTFLH-LRHEVGVIEHRDGGVFAIAVLSES +SVQRQPAAEQALGAAASLL---- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E0S076_9CHLR +--ALRSNVLGIIDEFSGTASVSANNLTTGDLL-DINEKEVLPALSAIKIGIMAELFFQIE +DGKYNLLDRVTVNASDLRGGTGVFREMETPLVTLKDLCMMMIVVSDNTCTWMLSSML-GL +DAINQRMRSLNMNEYSLNHDLPTAFDDMQGDAYSECSARDFTTLVTLMAKGELVSKTSSD +AMLDIMGRCQH-IEWLGRYLPPKVKLYNKLGAYLH-ARCDTGLIKSENSD-YVITVFASY +SKDEPHEGSRLIGKVSKAVYDAw +>[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A538RT92_9BACT +------------------------------------------------------------ +--SIKLTDPVTLREEDKVPGSGVLTHYFSAGFPLKDAVRLMIDVSDNTATNLVLDKI-GI +ASTGKRMAAWGFPETKIHAKSFRGSTRSKRYGLGSTTAREMVGILEKLQRGKAATPEGCK +EMLAILQQCED-KEKFPRFLPEGVKVAHKTGSLSD-ARTDAGILSWPAG-PVALCMLTNN +NEDHDNAGNVFCAKVAREVYDYf +>[subseq from] serine hydrolase n=1 Tax=Kocuria sp. UCD-OTCP TaxID=1292021 RepID=UPI00123756D1 +------------------------------------------------------------ +----------------------------GLGLTVEQALDVMISWSDNASGAALGQWL-GW +EQVEAFAHEQGFTDTTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSTA +LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG +WS-DYEESAPWFGDAGR------ +>[subseq from] Beta-lactamase-like protein n=1 Tax=Amycolatopsis azurea TaxID=36819 RepID=Q6WSB4_9PSEU +--EVAETINTRAKEAGVRVRLHAAEIDGTRRI-GIDEHAPVVTASVFKVPIALELARQGA +DGELDLGEPVTVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILARV-GK +EPTEKSLRRLGFEHTTVPQDCGEVLDALQPAHTCATTAEEITRLLGLIWRDEAASPAACA +DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVQYPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] Serine hydrolase n=1 Tax=Propionibacteriales bacterium TaxID=2015801 RepID=A0A6A7MLE7_9ACTN +-------------AVGGEVSVWCGRADGTPVW-TRLPDQQHYAASTMKLPVLVAAHRRAA +AGGLDLDAAVPVHNEFASVGSAYSWDAIGTSRPLRWLTQRMIVRSSNLATNLVLDQV-GV +PAVAEALDACGSTATTVARGIEDYQAR-DHGLDNMVTAPGLAAVLVTLVAERAADPAACK +EILDVCAANEW-NDGIPAGLPAGTRVSHKNGWQNR-VCHDAALVQPADAEPFVLVVLTTT +DL-ERSAADALTARIAAAAYT-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2D6R0B9_9BACT +--RLERAIERGATVAGGLVGATAIHLESGRTV-SVNGDEAFPMASTYKVPIAIELLTRAD +AGTLSLDEMLDVMAADLHPGSGTLSPLLAQPLSVRNLMELMLRISDNSATDMLLARAGGS +EAVTGRMRMLGIDGIRVDRPTAVLI----------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=A0A328NH39_9ACTN +------------------------------EV-GVRADEQVVIASIFKILLVLEFARQVE +AGQLDPTERVVVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP +DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA +EQPRRIDVDLAMGEAARTAV--- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535NWA4_9CHLR +--RLSADLALIAGTSGGRVGISLQELSGPRSL-SVNGGQSFVAASTYKLPLLMAEAQQIA +SGQARPSDLLCYAPGDAEDG-WFTDYQPGSCFTRDQLALRTGRYSDNTAAHILVRYLGGA +DALNRYAKSMGMTNSAL--WT-----------PNTTTPDDLSQALVSEALGRLGGAAAQA +WLYPILTHTAT-ERAIPAGLPAGVTVAHKTGSMP-GTENDAAYVRNG-RIAYVLSITVDG +LD--EGTAWSLMARISARVWQY- +>[subseq from] Beta-lactamase class A n=1 Tax=Humibacillus xanthopallidus TaxID=412689 RepID=A0A543HWK5_9MICO +--DLVARLDALASDDSASVSVWLGDLAGRCRW-SHRADAPHYAASTMKLPLVIAAQRRVV +RGELDLDAPLPVRNASVLDGSPFTWAAVGATRTLRELAEHAITHSGNLATNLLLDVV-GR +DEVAEVVRLAGCSPTVVGRGIEDAVA-RAAGITNTVTAADLGLLMAAVARRELGGPPVCE +PVEQILERQQH-VDQIPAGLPSGTPTASKSGWIP-GVSHDVALVRPAGEDPFVLSICTTI +EL-GEHEAAAFVASVAADVW--- +>[subseq from] N-acetylmuramoyl-L-alanine amidase n=2 Tax=Streptococcus sp. DD10 TaxID=1777878 RepID=A0A139NA43_9STRE +-----NEYNRLFGNIGGQKSLYISP-VDGTEY-RLVNDSVQPSASSIKLFVLAAAYAKAA +RGELNLQQRYTVQQSDIIPNQAVTLNLYGKAYNLDQLLHFMTSTSDNSATNIIIRHIGGV +DAVNNEIRRLGYNHSTLNRYMYDSA-AISRGVDNYISAQESGDLIKNIYNGTLIDKATDA +AILEKLAHNVH-NYWLTANIRDKAQLWEKPGGSGSGTENDTAIIKKNNRA-YAVSLLTYG +ATNQNSA---------------- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. WP24 TaxID=2604469 RepID=A0A5D0TC52_9ACTN +-------LDAHLDTVPGTVSAYVGRPDAEPAW-TRRADATHYAASTMKAAVLAALHRAAE +AGALDLDAPVPVVNSDSAQGAPRFWARVGGAAPLRWLAHRMIVRSSNLATNLVIGHV-GL +PAVAEVWSLAGARHSVTGRGIEDFAA-RDNGITNLVTAADLAALLGALATGAIASPAACA +EMLDVLVAQEH-REDLAAGLPPGTRIAHKNGWVR-GVRHGAGVVFPDDAAPYAVVVCTTR +DAEDDADACALIADVSARVWS-- +>[subseq from] serine hydrolase n=1 Tax=Kocuria rosea TaxID=1275 RepID=UPI0011B22814 +---LAADLEELAAEVPGELGVVLLDPEGGEVV-ARNADRPFTSASLYKLFLAHAVLDRAD +RGALALSDVV-----------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW +EQVEAFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGSSTA +LLMGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG +WS-DYEESAPWFGDAGR------ +>[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=K2CUN5_9BACT +--NLKNAVENVLAGTKGTYAVAIKNLKTGESY-FANEHKSFEAGSLYKLWVMAAVLSKIR +DGTLSEEQVLSRDISALNEDSEVAELTEGKILSVNDALTQMITISHNYAALLLTEKI-KL +STVANLLKEKGFGESKVGRGDD----------VPHTTPYDIFLYFEKLYKGELAQPEDTE +KMLVLLKNQKL-NGKLPKNLPKDTVIAHKTGEIGW-FTHDAGIIYSDKGD-YIIVAMSET +DKP--AAAEERIARISESVYRYf +>[subseq from] Uncharacterized protein n=1 Tax=Kutzneria albida DSM 43870 TaxID=1449976 RepID=W5W878_9PSEU +--ELIRTITDRATEVGVRVRLHAVDLDGSRQV-GIDATTPVVTASVFKVPVALELARQGA +VGELDLAEQVRVAPGHPTAPYGLATFRHAVTMSWYDLAVLMIGISDNVATDLIMGKV-GK +SAVASLLRRLGFAHTAVPQDCGELLRALRPEHTCRTTAAEITRLLGMIWRDEAAPAAACA +DVRRWMGLQVW-PHRLRSGFSDEVRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGVFTQA +IDSAVPQRDAFIGFAAERAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Woesebacteria bacterium RIFCSPHIGHO2_01_FULL_41_10 TaxID=1802500 RepID=A0A1F7YLR1_9BACT +----IAAFEDTTRGLSGVYAFYVYDLTSGVSY-GIHQEEMFQAASLIKLPVLAALYMESE +AHRIQLTSEYSLREEDKIGGSGSLQYAEEGSYTFAELAELMGKESDNTAFGIVRNRL-GD +KKINSVIDTLGMHDTSLS--------------ENQTTPSDIGRFFRKLWEARLISRESRN +EILDHLTDTIY-ENHLAAGIPDDVPTAHKYGREVH-IVNDAGIVLSEN--PFVVVIMAKG +VVES--EADDVFPTLSTLLF--- +>[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium ulcerans 12-1B TaxID=457404 RepID=H1PRI9_9FUSO +----EERIKKIIEENSGVTGVIIRD-SSGKMI-TINEEVVFPSASIIKLFILMALNKD-- +----EYNKKIELKKEDKVGGCGILKVMGDGLLTVKDAAYLMICLSDNTATNILIDYI-GM +DKINECIREKGFTGTVLGRKMMDAEAR-KAGKDNFTTPKDVLGVLEMLCGN----PD--- +-DLDMLRNQAY-NNKIPLYFAREVDFAHKTGELMY-IEHDTGRLFYDGG--WVDVIVLTK +DLEKNEDGIKINSLIGKVIFDNy +>[subseq from] Serine hydrolase n=1 Tax=Clostridium sartagoforme TaxID=84031 RepID=A0A4S2DID2_9CLOT +-----KEIKKYLESRMGTYGFFFEDLKSGFIY-GYNENVQITAAGCMKLPIAVSLIKAVE +DKKHDFLDKIKIESKDKVYGTGIIHEFSEREYTLFELLVAMLIQSDNTAANKIIDIL-TM +DKINEDIKGMGLRNTVLNRKTTDERNA-KDEIENITSALDLSKIWKHLYNGTYLNRENSQ +MLIDILMRQQI-KNKLALYIPDDYEISSKTGDKA-GVENDTQLIRLSKGN-FSFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] serine hydrolase n=1 Tax=Plantactinospora sp. BC1 TaxID=2108470 RepID=UPI000D16ED9C +------------AALPGTVSVYAGRLGRRPAY-TRLPDTPHYAASTMKVAVLAALYRAAE +AGEVELDAPVPVVNEFDSAGAGRFWARVGGTAPLRWLAERMIVRSSNLATNLVLGHV-GL +PAVAQVWADSGARHSHTRRGIEDFAA-RDAGLDNQVTAADLARLLGGIARSRLASPGACA +AMLDVLLAQER-GEDLAAGLPPGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYAVVVCTSA +PPDRDARARRLVARVSALVWA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 4121.5 TaxID=1938847 RepID=A0A2N0EI76_9ACTN +------------------------------EF-GFRADEPSVPASVVKVQVALEVETWFA +EGRLDPGERVTLSAADRTPGPTGTSLFEDDVLSWRDMVVLMLTISDNHTTDVLLRRI-GV +AAVNATAERLGLTGTVLESDLRTMLDALDPSRGTRTTPRDMAELLRLIWTDRAGPAAACA +RVRTLMGHQLT-RHRIASGFRPPVRVAAKSGGLLGVVRNEVGVISHPDGRRYAAAVFTRS +RPSDETAINAAIGAAARAV---- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V7A0L4_9BACT +--DLVKRLNELSDSAEFEVSWYLRDLASGATA-NRRGDVAVPSASTRKISIMMAALAAVH +AGKLALDQKVTIDARFQDNDSGTFQHLTPGFITLRDAMVMMIIVSDNTCTGHVVDLV-GL +ANVQRYTETVGLTGTVHRYGIPKTGADNTLDRVTTTTANDQGLLLELILKGTACTPALCR +LGLDILSWQKL-KTRLPSLLPLGTKVAHKTGTGHR-CYNDAGIIFKEERPLCVLTAYTVG +VPPGFAAAYQLIGRMARMS---- +>[subseq from] hypothetical protein n=1 Tax=Candidatus Syntrophocurvum alkaliphilum TaxID=2293317 RepID=UPI0012E2DDC1 +------KAAEEAKKSDNRLRASVYDFATNTTV-NYNGNQRFYPASLTKVLNLLCYLEEVE +RGNKYLNSTYKLKESDKYIGTGSLQHQEEGTYTFDRLLSLMISISDNVASNIVLDAL-GT +DRVNSFAVRHYLNDTRVFRKFYDFSTN---KSYNYSTTVDLTRKLVLLENRQVVSDYLSS +KGISFLEDTAD-KNKIGRYAPDNVVVANKIGVLSR-MSGDMALVYFPHREPIALTIVIED +KERELEEADKIIGTLSKELIDYy +>[subseq from] Beta-lactamase class A n=1 Tax=Kineococcus rhizosphaerae TaxID=559628 RepID=A0A2T0R7V4_9ACTN +-----------------EVTFWAEDLFSGRGA-RHRADEARPVLTLSAGLALGLLLS--D +RGPHALTGRVRYSATQLVRSSPVCAWHVQDGLSVAQLGDAALRRADATATNLLVARAGGA +AALTAFCRRLGDRRTRVDRAAPDSCTGAPWDPQDTTTTAALARTYGALLLGRALAPGARS +QLLDLLPTT---------GLTGGWAVTHAVASGRYGTAALVGTARRGRR-QVLVAATVRA +GQPA------------------- +>[subseq from] Beta-lactamase n=1 Tax=Microgenomates group bacterium GW2011_GWA1_48_10 TaxID=1618496 RepID=A0A0G1U677_9BACT +---IQNYLQAETGKLPGNYCVYIKDLKRGATY-KVNANQPLATASIYKLAVMYKTYDAIN +RGELKKEDVLTEDESTLDQLKPEADTNTSGTYMVADALRAMITVSDNYSALLLADKL-GW +KNIDDFLKQQKIEGFDLV-----------GGQQPTATAEAVAILLERIFRNTAVNSQSSE +EMKGLLLAQQV-NDRIPKYLPKDTKVAHKTGELDN-FRHDAGIIYGKNST--YIFVFLSE +TPAPG-DAVENIANLSQKMY--- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. KC207 TaxID=2530377 RepID=A0A4R4SBW0_9ACTN +------ELDARLDALPGTVSAYAGRVDAPPTW-ARRPDATHYAASTMKVAVLLALHRATE +AGTLDLDAPVEVRNESALPGAPRFWEREDGHVPLRWLAERMIVRSSNLATNLCLRHV-GL +PAVADAWAIAGARHSVTGRGIEDFAAR-EAGITNLVTAADLAALLGGLAAGALASPAGCT +AMLDVLSAQEF-REDLAAGLPDGVRVAHKNGWVR-GVRHGAGVVYPPDAPPYVLVVCTTG +DPAD--DTCRLLADISARVWA-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL WC-3626 TaxID=1463926 RepID=UPI0004BF9893 +----------------------------AREV-AVGADDAVVIASIFKILLVLEFARQVV +AGQLDPRERVRVTSADRLGGWGTAGCLDDVELSLRDLAYFAMSVSDNSAADLLLGRV-GL +DTVGLLAKELGLDRTRVVGGPRDLLDVLDPHHTTASTPREITRLLRLVWTDAAGPPEACA +LVRDLMGRQVF-RHRLVSGFPDDVMVAAKTGTLP-GLHMEAGVAHYPDGERYAIAVFART +HDASRATVDAAIGRAAG------ +>[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DBFE019 +------------------------------EV-GVRADEQVVIASIFKILLVLEFARQVE +AGQLDPTERVLVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP +DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA +EQPRRIDVDLAMGEAARTAV--- +>[subseq from] Beta-lactamase class A n=2 Tax=Kribbella sp. VKM Ac-2566 TaxID=2512218 RepID=A0A4R8DKT0_9ACTN +----NARIRGIFEDAGVRGWMHAISLEDPQASvELDADVVVPLASVYKLPLLAGFCRLVD +LGELDPRERVTLEPSARTAGPTGLSAFADPVVSLRDLALSMATVSDNASADALLDIV-GL +RRLAEILESFGLRRTWVRRGTAANLRVYEAANGSAASARDLTLLLRRLWAGELLSASQTE +FVKTTMHRQIF-LHRLASGFPDGVRVAGKTGTFG-ALRHEAGVVTLPGGAAFAIAVLTLA +ARGDQPRVDAAIGEAARVAVD-- +>[subseq from] serine hydrolase n=1 Tax=Kocuria rhizophila TaxID=72000 RepID=UPI0011A67959 +-------------DMTGAVAVRVIDAPELPAF-GWRADEAFPAASLYKLVVMVAFCRAVD +RGDLDPTALVTLRPEDRADPTGLAICQDPVRISWRDLVRLMMTVSDNAAGQAVLREV-GH +ARVWDVLREMGLSSTVVRPG-PAPDAGYDPLLVSATTASDLVALLCAIWQDRAASTAQCA +FMREVMSQQAWGHRFAEAFSYPGAGVAAKTGSFG-ALCHEAGVISHPGEKSIAVAVLTRS +VRRQIAVSNRIVGQIARHCVRSy +>[subseq from] serine hydrolase n=2 Tax=Kribbella sp. VKMAc-2574 TaxID=2512112 RepID=UPI0010648FD3 +----NARIRGIFEDAGVRGWMHAISLEDPQASvELDADVVVPLASVYKLPLLAGFCRLVD +LGELDPRERVTLEPSARTAGPTGLSAFADPVVSLRDLALSMATVSDNASADALLDIV-GL +RRLAEILESFGLRRTWVRRGTAANLRVYEAANGSAASARDLTLLLRRLWAGELLSASQTE +FVKTTMHRQIF-LHRLASGFPDGVRVAGKTGTFG-ALRHEAGVVTLPGGAAFAIAVLTLA +ARGDQPRVDAAIGEAARVAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Sporolactobacillus sp. THM7-4 TaxID=2511170 RepID=A0A4Q4IFD4_9BACL +---FINKLKSLTEPLGDQIAIAAEG-SDGFRF-LYNESVPMLSASLIKLPVLLYVYDQAK +IDRSILKKTIVLRNHEIVGGSGVLQILSGREWSVRDLLALMINVSDNTATNLLIEEF-GI +RPIQQWVREHGYKETTLERKMMDTAA-EDAGKRNLISARDACQAIRTLFSDQ---KAYPD +EIKSWFLHQQF-RGKLPGEVPNPVSVYNKTGEMEE-IDHDAAFFSYKSS-SMSIAVLTSG +VK-DRQIALSVIQKIGKSVSDY- +>[subseq from] Beta-lactamase protein, beta-lactamase n=1 Tax=Microgenomates group bacterium GW2011_GWC1_39_7 TaxID=1618515 RepID=A0A0G0PGJ3_9BACT +-------IGKFLKTIKGTYSIYYKDLKTGEEF-GIDENKVLTAASLTKVLIIAYLYNQAN +KGKINLEDKIVIQKDDIQDYGTGSIRYEGEGYSLKQLIKLALEQSDNTAAHVLVLKL-GE +GKVQEFGARLGLAATNMKN--------------NKTSAQEMGRLFELIYLKKITSEPLTR +EFLDFTKDTDF-EDRLARDLPSNVAMYHKAADATN-MVHDAGIIDD-GKNPFILSILTEN +IA-SEEEAKKNIGKLAKFIYDQ- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Cryosericum terrychapinii TaxID=2290919 RepID=A0A398D1A7_9BACT +-------------------------TEDRCLIfSQNSNLPFGAASIIKLPLLVCVAQLVE +LGELAWDRAIRLTVAAP-HGTGLLEYLDKSGWSVQDLCIMMMGVSDNMACNQLIEEI-GI +ERLNDVLHDLGYEATSIRRQMMDRET-LARGIDNSVTAADIADMLARLHAHRLVSNAASE +RILGYLRMNQL-RDLVAWPLPGSAALAGKTGGMS-GSLLDAELITVSGGPTYSLCVFASG +FE-RAAQAKRVMAEVSEMIYS-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DBFA224 +------------------------------EV-GVRADEQVVIASIFKILLVLEFARQVE +AGQLDPTERVLVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP +DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA +EQPRRIDVDLAMGEAARTAV--- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium HGW-Chloroflexi-9 TaxID=2013732 RepID=A0A2N2LEC2_9CHLR +-dALAARLNALADEAPFHIGWHLTDLRTGASA-DRNGGVVVPSASTRKVAILLEALRGLH +EGRFDLERRITVDELVKTTSGAFQWFRPGFTVTFHDLLLMMIIVSDNTATGLVTGMV-GL +DRVQALCDRIGMTGTAHRRATPDYSRDPGPGVTNDTTPNDQGRLLVAILEGAGVTPDLCA +YALDLMSKQRL-RTRIPSWLPEDVKVANKTGSLG-GNHNDVAVVYEGDE-PLFVFTYFAD +H---------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7GN38_9BACT +------------------------------------------------------------ +--------------------------RVGQKASVRDLLELMITVSSNLATDILIERV-GP +ARANATAHALGADSILVLRGVEDGV-AYRAGRNNTTTARDLGALLAAIAEHRAASRVACD +SMLAILGRQHF-TEGIPAGLPPGARVYHKTGWVGQVVYHDAAYVEMPGGRRYVLVVTTGG +IQLD-TAAYHLVADVSRIIS--- +>[subseq from] Beta-lactamase class A-like protein n=3 Tax=candidate division WWE3 TaxID=422282 RepID=A0A0G1DCW5_9BACT +--KVETQFVELTKKLPGVYGLYIKDVGSGREF-KYNDATEFYAASLYKVPLAAAVLKEVE +AGKLKLDDTATYLPYDYSSGTGVISTYSHGILKISDILSELLKNSDNTAQNILLRTL-SY +KNVQETFNAV-----VPDKNTSTYY------RYNLSTPAEISFVFEKLYFGDYLNAEDKK +YLSDLMVNTSF-EDRISAYLKDGLVFSHKIGSWPD-SWHDCGVVSSEANSKLIVCLMSQK +A---------------------- +>[subseq from] serine hydrolase n=1 Tax=Kitasatospora azatica TaxID=58347 RepID=UPI00055EFDA2 +----TDKISAVFEQAGCEGTLCVQSLDGGAEV-AVRADQQAVLASVSKVLIALEAESCFA +DGRLDPGERVTLGAVGRTPPTGISLLQDDVVLSLRDMVVLMLTISDNHTTDELLRRI-GV +DAVNAMAARLGLTSTVLESDLQTMLDALDPAKGTRGTPRDLVRLLRLIWTDQAGPAAACE +RVRGIMAKQLT-RHRIAAGFRRPVQVAAKSGSLIGVVRNEIGVISYPDGRKYAAAVFTRS +RPADEFAINAAIGSATARA---- +>[subseq from] Serine hydrolase n=1 Tax=Kocuria indica TaxID=1049583 RepID=A0A4P6RMB4_9MICC +-------------DMTGAVAVRVIDAPELPAF-GWRADEAFPAASLYKLVVMVAFCRAVD +RGDLDPTALVTLRPEDRADPTGLAICQDPVRISWRDLVRLMMTVSDNAAGQAVLREV-GH +ARVWDVLREMGLSSTVVRPG-PAPDAGYDPLLVSATTASDLVALLCAIWQDRAASTAQCA +FMREVMSQQAWGHRFAEAFSYPGAGVAAKTGSFG-ALCHEAGVISHPGEKSIAVAVLTRS +VRRQIAVSNRIVGQIARHCVRSy +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003700992 +----------HLDRMPGTVSAYLARLDAAPTW-TRRPDTTHYAASTMKVAVLVALHRALA +AGRLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLRWLAERMIVRSSNLATNLLLNQV-GL +PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPERCT +AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS +DRPDHSRDEDACQLLADLSA--- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora echinofusca TaxID=47858 RepID=A0A1C5G6U3_9ACTN +------ELDARLDGVPGTVSAYVARVGAAPAW-TRHADATHYAASTMKAAVLVALHRAAE +AGTLDLDAPVPVRNESALPGAPRFWERVGDDVTLRWLAHRMIVRSSNLATNLVIDHV-GL +PAVARVWDLTGARHSVTGRGIEDFAAR-EAGVTNLVTAADLAALLGALAAGALASPAGCA +AMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYAVVVCTTT +DLEEDDDACRLIARVSAAAWD-- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 01416 TaxID=2203196 RepID=A0A429C7G6_9PSEU +---VIETINDRAKEVGVRVRLHAAEVDGTRRI-GVDEHTPVVTASVFKVPIALELARQAA +EGGLDLGERIAVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILDRV-GK +ESTEKSLRRLGFEQTTVPQDCGEVLGALRPEHTCATTAEEITRLLALIWRDEAAAPVACA +DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTEA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6Z743_9BACT +--DLVKRLNELCDAAPFQASWYLKDFATGASA-DRRGDVPVPSASTRKISIMMAALAAVH +AGKLALDQKVTIDARYQDNDSGTFQHLTPGFITLRDALVMMIIVSDNTCTGTVVDLV-GL +PNVQRYSESVGMTGTVHRYGIPKLGPDNSLDRVTTTTPNDQGLLLELILRGTQCTPALCR +LGLDILSWQKL-KTRLPSLLPLGTKVAHKTGTGHR-CYNDAGIIFKADRPLCVLTAYTMG +VPEALA----------------- +>[subseq from] Uncharacterized protein n=1 Tax=Kocuria rosea TaxID=1275 RepID=A0A2V1MAT1_KOCRO +------------------------------------------------------------ +----------------------------GLGLTVEQALDVMISWSDNASGAALGQWL-GW +EQVEAFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGSSTA +LLMGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG +WS-DYEESAPWFGDAGR------ +>[subseq from] Beta-lactamase class A n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A2H1IZ67_9MICO +--RLTREVSDELEAAGLRARIVVRDLDSQAEI-SIAHDGPVPLASVVKVPIALAILNRIA +DGRLEADRQVHVAPGRFEGGSPMGTSRFRHPIAVDDLLMLSVCFSDNTATDALLDLV-PT +EEVQRDLDDLGLGGIQIRHHLDALVRQLDVSQANVATAAGLTDLLAELWRPERIQTSAAS +RLRELMAGNVVRHRLAPDLMSDAAKWSSKTGTLLH-LRHEIGVVEHSDGQTIAVVVLSES +SNAVQPAAEAALGAAARALH--- +>[subseq from] Beta-lactamase class A n=1 Tax=Bacteroidetes bacterium HLUCCA01 TaxID=1666909 RepID=A0A0P7WGD0_9BACT +-------FRNIESLLEGTLHVAAIEVQSGKTW-SYQSDTPVSTASTIKLPILIHTAMQAG +NGELAWDSQIPVQKDDLVGGMGVLRHHTPGTVRLDDACYLMTSLSDNTATNLVLDQT-GI +EPVNESLNIFGCANTRLYRKVPDTPES-MEFGLGVTTAADMLRIMQLLYAGVSLPDERAV +EFCKTMLDLQQDRVGVARIVPDAWTYAGKTGRVTS-TRGEAAMVSAPDGRMWLLGIFVHG +LT--------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora chokoriensis TaxID=356851 RepID=A0A1C4X0P4_9ACTN +------DLDAHLDRVPGTVSAYVGRLDAPPTW-TRHPDAAHYAASTMKVAVLAALHRAAE +AGTLDLDAPVAVVNED-SAGAPRFWDRLGATATLRWLADRMIVRSSNLATNVVIGHV-GL +PAVADVWASAGARTSVTGRGIEDFAAR-EAGITNTVTAADLAALLGALASGAIASPAACA +AMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGVGVVLPDDAPAYLIAVCTTT +DPDDADDACLLIADVSARVWA-- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Arsenicicoccus sp. TaxID=1872639 RepID=A0A2W6V2N0_9MICO +----------------------------RHEV-SYAADDLVPMASLYKVLLALAWARLVD +AGDLDPRARHTVSAPDRTPGPTGLSSLEDEVVSQRDLVTLMLTVSDNAAADVLLDLV-GL +PRLREVAADAGMTATTLHGGTRHHQRVYDPAMSSTTTARDMTRLLGALWREELVAPESGA +RIRRSMARQVF-RHRLASGFPDDVEIASRTGSLLT-LRHEVGVVTFPGEEPVVVAVLTQ- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Agromyces sp. KACC 19306 TaxID=2592652 RepID=A0A5C1YCQ3_9MICO +------EAARVLDDAGLTASILVRDLATGREL-AHRADAPYPLASIVKLPLALAVLRAAE +TGDLDLAEPVRLDPGRRTPPTGTCRFEYAAEIAIGDLLSLAMCVSDDTAADALFDRC-SP +DAVTAVLREVGVEGITVRHRIRDLHEQLDVTGANAGTARALVDLLERIWGDPALA-RERE +PLRRLLSGNLVRQRLAPDLESDDAEWFSKTGTFLH-LRHEVGVIEHRDGGVFAIAVLSES +SVQRQPAAEQALGAAASLL---- +>[subseq from] Uncharacterized protein n=2 Tax=Saccharothrix espanaensis TaxID=103731 RepID=K0K8V2_SACES +--EVVREIRSRAEEVGVRVWLHAVEVDGTREL-AVDADDPVPSASVFKVPVAVELARQGA +AGEVDLGERITYVAGTGTMPFGLATYRHDVTISWHDLAILMIGISDNVATDLVVDRI-GL +PSIARLLAELGLKHTAVPFHCDGLFQILQPAETCRTTAEESTRLLGMVWRDEAAPAQACA +DVRNWLGHQVW-PHRLRSGFHEGIRVFGKTGTLPM-VRNEIGVVEYPDGGRYAVAVFTQA +HDAQAPERDGFIGFAAARA---- +>[subseq from] class A beta-lactamase n=1 Tax=Kineococcus rhizosphaerae TaxID=559628 RepID=UPI000D0667B4 +-----------------EVTFWAEDLFSGRGA-RHRADEARPVLTLSAGLALGLLLS--D +RGPHALTGRVRYSATQLVRSSPVCAWHVQDGLSVAQLGDAALRRADATATNLLVARAGGA +AALTAFCRRLGDRRTRVDRAAPDSCTGAPWDPQDTTTTAALARTYGALLLGRALAPGARS +QLLDLLPTT---------GLTGGWAVTHAVASGRYGTAALVGTARRGRR-QVLVAATVRA +GQPA------------------- +>[subseq from] Serine hydrolase n=1 Tax=Plantactinospora sp. BB1 TaxID=2071627 RepID=A0A2R4FTY4_9ACTN +------------AALPGTVSVYAGRLGRRPAY-TRLPDTPHYAASTMKVAVLAALYRAAE +AGEVELDAPVPVVNEFDSAGAGRFWARVGGTAPLRWLAERMIVRSSNLATNLVLGHV-GL +PAVAQVWADSGARHSHTRRGIEDFAA-RDAGLDNQVTAADLARLLGGIARSRLASPGACA +AMLDVLLAQER-GEDLAAGLPPGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYALVVCTSA +PPDRDARARRLVARVSALVWA-- +>[subseq from] Uncharacterized protein n=1 Tax=uncultured Ruminococcus sp. TaxID=165186 RepID=A0A1C6KGS0_9FIRM +------------------------------------------------------------ +--------------------------------TTKHLLDEMITVSDNSATNELVRYLNGM +KKVNAFIKAQGFEYTHEYNGLEDTSLWYDTDTKNTTSAKDCGRLLERIYRGEFVSHLASR +QMEELLLNQQV-TYKIPSTIPSESRVANKTGETSD-CENDAAIVYTPKGD-YILCIMSCE +VS-SKNSAVDSLQEMSSLIYSYf +>[subseq from] Beta-lactamase n=1 Tax=Ruminiclostridium hungatei TaxID=48256 RepID=A0A1V4SG80_RUMHU +--ELKKLITDYTSKLSGKYGVTYIDLATGEMV-NVNDQIEYIAASTSKLPINMVLFKDIE +AGKVTFDEKLVYKQEDMEPGTGIIQSSAYGTYTVRKTSELSIKKSDNCGVNMIIRRV-GI +ENVRQYLVDLGGKVYY--------------GKTHRSCPYDMALVAKDLYIHYLNNETVFG +ELINNMENTNW-SDRIDAKLPQEVKVAHKIGNQTK-TANDVGIVFAK--HPYVLSVMTDN +VD--FGTACNNIAGLSKKIY--- +>[subseq from] serine hydrolase n=1 Tax=Halorussus salinus TaxID=1364935 RepID=UPI00109334AB +-dELAEYVESYADRIDGRLGVFLGFPREFDAVvERNAATAFAAASVIKLPLLYALYDEYD +GRLAELGERREIAPRNRVAGSGLYHLLDSPDPSVEDLARAMIAISDNAATNELIDLL-GM +ERIEETAADLGMARTRLRRKMMATVGWPEGEPANATAPADCARLFADLIHRATLSEAAYD +RLAVPLREQKH-AMLFPRYFPMDVECVHKTGQLPS-AALDAGYVEPPGKA---------- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DC04A33 +------------------------------EV-GVRADEQVVIASIFKILLVLEFARQVE +AGQLDPTERVLVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP +DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHATSSTAREITRLLTLIWRDEAGPAAACA +MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA +EQPRRIDVDLAMGEAARTAV--- +>[subseq from] Serine hydrolase n=1 Tax=candidate division WWE3 bacterium TaxID=2053526 RepID=A0A3A4ZAX6_9BACT +--KLIETLKNELNQLEGHVALKVKFLNTGDIF-EHNPDLQLWAASVIKVPIACEFFRQVS +ESKFDPQTRIMVSEDNFVDAAGVIKHLSRDIYPAIDLVKLMLIVSDNSATNQIIDLV-GW +ESIEKYTQELGLRDTTFRHKMMI--K--AGRGPNLTTANDMTSLLEMLYNHKL---SGSQ +EILDYMNEQLD-RTRIALYLPNDIKVPRKYGSLPE-AMHEVGVVYSK--SPFIFSFLSDD +Q-KDKRMTNEILSKCAKYCFD-- +>[subseq from] Uncharacterized protein n=1 Tax=Deltaproteobacteria bacterium 13_1_40CM_3_69_14 TaxID=1805116 RepID=A0A1Q7M103_9DELT +--------------------VSFHDLETGERI-ELRARESVHAASTMKLAVLLAAYRLG- +---LPLDQPVRVENRSIADGSTFAYTQLGKEVPLQVLLEHMIVRSSNLATNLVMLKL-QA +AQVERVCRDLGANDIRVLRGVEDLKA-HEKGLDNTATAHDLALLLEAMP------PP--- +-AVEILSRQEL-NEGLPAGLPKGTRVAHKTGEIDR-HYHDAGLVFPPGRKPYVLAVMTRG +FE-TKEEAAAVVREISRTVWR-- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 01376 TaxID=2203195 RepID=A0A428XKZ5_9PSEU +---VIETINDRAKEVGVRVRLHAAEVDGTRRI-GVDEHTPVVTASVFKVPIALELARQAA +EGGLDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILDRV-GK +ESTEKSLRRLGFEQTTVPQDCGEVLGALRPEHTCATTGEEITRLLGLIWRDEAASPVACA +DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTEA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Kribbella amoyensis TaxID=996641 RepID=A0A561BXX0_9ACTN +--------------ARGAFGVWLGRLDGLPVF-QHRAETTHYSASTMKLPVAMAMMRRVA +AGELALDQPIQVHNDFASAEAPATWTRMGAKVPLGWLATEMITLSSNLATDLVLEQV-GV +DAANAVLAEYGSGASVIRRGIDDAAAQ-RAGISNLMSPADLAAVLVAVGNDKT---PGGE +YVRDLLAGNQW-NGEIPAGVPAGTRVEHKNGWDTT-IRHDGGIVYPPDAEPFVLTACTTS +ELPD-AEAQRLIAAIATEAWQH- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 54-19 TaxID=1895928 RepID=A0A1Q3T4A6_9CHLR +---------------DAGFGMVIHNLDTGEKF-EVNADQLFESASLYKIFVALTVYYDMA +GGRMSPNDQITLIPADAHDEDGYTIVSVGDSLPVSTLLEKMIVDSNNTAGLMLLFQV-RA +TRMKQIAADLGFTGSDFSDTYN-----------FQVTPTDLDLYFSRLADLKLMGAKYDQ +PLLDLLSRSLP-RDRIPAMLPEGTHVANKTGNLG-GVINDAGIIWLPNGNRLIVSVLTHH +VDED--AARQFIAELSLAAYNYy +>[subseq from] Beta-lactamase class A n=1 Tax=Frankia torreyi TaxID=1856 RepID=A0A0D8BAH1_9ACTN +------------TQAGGRRAVAVEALRGPAVRvEVNAHTPQPGASTLKLIVAAAVHDAAD +AGQIDLSERVNCRDLHPTIFPTVMAAFDDGDLALRQLCALMLITSDNAAADALLDRV-GH +DTVNATARRLGATATTLAVDFRDEQLG-AAGRRNTTTAGDLNLILRGLAGHER-----YR +PVLASMRNNLR-NTRIPARLPDRTPVAHKTGSLD-GVVCDAGIIYGQHTD--VAVAFLAD +GESDSARTSIAIADTVATIW--- +>[subseq from] Beta-lactamase class A n=2 Tax=Moorella thermoacetica TaxID=1525 RepID=A0A0S6UD24_MOOTH +-tTLQQQIQNYLADKPGTYGIYFKDLASGQSF-GINADTPLPAASTVKLPAVLFINSLVD +QGVLDWQQKLTYNSADYQGGSGILQFSVKDGFTLRTLTTLAITTSDNIAYNMLRNFV-GK +GSIANYMQSLGGQTV------------FPG-GQNLSTARDMAIYVQAALNSAN-TSANGR +RLLDDMANGIY-NEGIPLKIPAGVTVAHKEGFVW-GSPGDVGVVFG--SRPFIITVLSQN +VP-DPDQGFANIATITRMIYDY- +>[subseq from] Serine hydrolase n=1 Tax=Planktothrix sp. UBA8402 TaxID=2055759 RepID=A0A3C1P963_9CYAN +--DLKTAIMGLAKDSKLKPGVFLVDLDTGNYV-DIQGEEALPAASTIKVPILVSFFQAVD +EGRLRLDEVLTMAEKHIAKGSGELQDQPGSKFTALETVTLMIENSDNTATNMLIDRLGGI +ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSAKDLVNLMAEINQGKLISLKS-- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Odoribacter sp. CAG:788 TaxID=1262909 RepID=R5PL24_9BACT +--TLQKQIRSILKDKKAMIGVAVLY-NGKITV-SVNNDQGYAMLSTFKFPLALAVCDYLD +RQKLPLETEIYVSKADLHPYSPLRDKQPEGDISIKELLRYCVSLSDNNACDILIRYIGGI +ERLQQYIADLGFPDMVIVATETQMHQQTGNQALNRTRPSAAVLLF--------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00035F5E68 +----------HLDRIPGTVSAYLARLDAAPTW-TRHPDTTHYAASTMKVAVLVALYRALE +AERLAPDTAVPVRNEFDSAQPGAAWDRLGGTASLRWLAERMIVRSSNLATNLLLDQV-GL +PAVADVWARAGARRSSTGRGIEDFAAR-AAGITNLVTAADLAALLRDLALGALATPESCA +AMLDLLVAQEH-RVDLAAGLPAGTRIAHKNGWVR-GVRHSGGVVYPDDAPPYVLAVCHTD +EHSDDTDACQLLADVSAHAF--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. LRa12 TaxID=2563107 RepID=A0A4V3T8U7_9ACTN +-----------------------------DEV-AVGADEPVVIASIFKVLLVLEFARQVT +AGQLDPRARVRVMAGDRLGGWGTAGCADDVELSLRDLALFAISVSDNSAADLLLAQV-GL +DTVRLLVKELRLERTRIVGGPRDVLQVLDPSRTNASTPREITRLLRLIWCDEAGPPQACA +WVRELMSRQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART +RESSRTAVDAAIGTSARIAVD-- +>[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Moorella thermoacetica TaxID=1525 RepID=UPI0008FB1B71 +-tTLQQQIQNYLADKPGTYGIYFKDLASGQSF-GINADTPLPAASTVKLPAVLFINSLVD +QGVLDWQQKLTYNSADYQGGSGILQFSVKDGFTLRTLTTLAITTSDNIAYNMLRNFV-GK +GSIASYMQSLGGQTV------------FPG-GQNLSTARDMATYVQAALDFARTSADGRR +-LLDDMANGIY-NEGIPLKIPAGVTVAHKEGFVW-GSPGDVGVVFG--SRPFIITVLSQN +VP-DPDQGFANIATITRMIYDY- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium ulcerans TaxID=861 RepID=A0A2P1S168_9FUSO +----EERIKKIIEENSGVTGVIIRD-SSGKMI-TINEEVVFPSASIIKLFILMALNKD-- +----EYNKKIELKKEDKVGGCGILKVMGDGLLTVKDAAYLMICLSDNTATNILIDYI-GM +DKINECIKEKGFTGTVLGRKMMDAEAR-KAGKDNFTTPKDVLGVLEMLCENS-------- +DDLDMLRNQAY-NNKIPLYFAREVDFAHKTGELMY-IEHDTGRLFYDGG-WVDIIVLTKD +LE-KNEDGIKINSLIGKVIFDNy +>[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Moorella sp. Hama-1 TaxID=2138101 RepID=UPI000D64B5E1 +---LQQQIQNYLADKPGTYGVYFKDLASGQSF-GINADTPLPAASTVKLPAVLFINSLVD +QGVLDWQQKLTYNSADYQGGSGILQFSVKDGFTLRTLTTLAITTSDNIAYNMLRNFV-GK +GSIANYMQSLGGQTV------------FPG-GQNLSTARDMAIYVQAALNSAN-TSANGR +RLLDDMANGIY-NEGIPLKIPAGVTVAHKEGFVW-GSPGDVGVVFG--SRPFIITVLSQN +VP-DPDQGFANIATITRMIYDY- +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0004891AB6 +------------DRMPGTVSAYLARLDAVPTW-TRRPDTTHYAASTMKVAVLVSLYRALA +AGRLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLHWLAERMIVRSSNLATNLLLNQV-GL +PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPESCA +AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS +DRPDRSADEDACQLLADLSA--- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacterium sp. XM4083 TaxID=2583238 RepID=A0A505HAA1_9MICO +-----DEINGVWTSLGAQGFLYAEHLGTHRSL-GIRESARIPLASVGKVAVIAGLLDAAA +DGTVDLAQRLLVDPAHSTPGTGIAGLLDPVEMSVRDLAAMALSVSDNAAADTLFDLV-GP +DRIMAVLHRGGIRSFEVTSPMSHLYDLLPDSAFNTGTVRATAKLFELIHTGQLLGPEGSE +TLRRLLRKQIF-RHRIAAGFPDAVQYYGKTGTFLN-FRHEAGVVVDSDGSAYSIAVFTRS +SIATQPELDASIGYCARLAIEH- +>[subseq from] serine hydrolase n=1 Tax=Nocardioides albertanoniae TaxID=1175486 RepID=UPI00114DCA61 +----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD +RGLLSLDEPTPVHPDD--QQDPETWAAVGSSLPLGDLVRRSLIVSGNLAANLVLERV-GL +DQVADVLEEAEVTMTTVSRGIEDAPA-REAGLQNLVTANDMGKVLTKLASGRLLSPESTA +ELTGALVDQHY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIHPSEGDPQVMVVLTTG +LDD--DESEFRISEVARYLWS-- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces qinzhouensis TaxID=2599401 RepID=A0A5B8JKL1_9ACTN +--------ARSAAALPLSLSVAAIDVDDGRST-GVDDTAVLPVASAAKLLLLAEVARGLD +AGELDPGRTVAVTDDDVVHGTGLLVRLSRRDWTVEDLCWLTASVSDNTATNALLRLV-GP +ETTARLARSLSLEALTLHDRVRDVRGPGDPPVFATGTARALAELVAHAARGSLVSPGASR +RLLGWMRSNTDYAACFPEPLPGGLLLANKTGTDP-GVRADAGVFIGARRVAYAVVAHWDT +ALGDSTERARAVRDVGRTLAE-- +>[subseq from] Uncharacterized protein n=2 Tax=Bacteria TaxID=2 RepID=K2C4D5_9BACT +-----------------NYSLYVKDYNSDFEL-GINEEVIYTAASVNKIPILSALYYYTQ +AGEIDLDESITLQEADIQDGTGVLRYTPGATYTIKTLARLMIQKSDNTAAYILLNNIVRI +ERTQKLMESWGLIQTDIAN--------------NKTSNKDISMLFEKIISGDVANQAYTQ +EMLSFLKDTDF-EDRLPAMLPKSVTVYHKIGTGVR-IIHDVGYVTDGNL-NYYVGIFTSD +VP-SEDDAVLLMAKLSKSIYN-- +>[subseq from] Serine hydrolase n=1 Tax=Kocuria rosea TaxID=1275 RepID=A0A4R5YHN4_KOCRO +------------------------------------------------------------ +----------------------------GLGLTVEQALDVMISWSDNASGAALGQWL-GW +EQVEAFAHEQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSTA +LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG +WS-DYEESAPWFGDAGR------ +>[subseq from] serine hydrolase n=1 Tax=Streptococcus urinalis TaxID=149016 RepID=UPI000F8332EF +--------------------------DGVEYA-ASRETVSQRSASTIKLFILTSAYEKAQ +RGELNMSSNYTVKSSDIVVASTALANSAGQTYSLDTIARFMVQYSDNTATNIMISAIGGV +SAVNAEIRRMGYTQTTLNRYMR-IQSQIDAGLENYINVHEAVDLLKNIYNNTLQNTTAEP +TMLADLSNNYY-KLWLPASIQSQAQTWDKPGNDGFGVENDIAAIKVNGK-TYIVGVLTQH +TGSNGVSNTGVFANFGKSIV--- +>[subseq from] serine hydrolase n=1 Tax=Frankia sp. CpI1-P TaxID=1502734 RepID=UPI000707ED6C +------------TQAGGRRAVAVEALXGPAVRvEVNAHTPQPGASTLKLIVAAAVHDAAD +AGQIDLSERVNCRDLHPTIFPTVMAAFDDGDLALRQLCALMLITSDNAAADALLDRV-GH +DTVNATARRLGATATTLAVDFRDEQLG-AAGRRNTTTAGDLNLILRGLAGHER-----YR +PVLASMRNNLR-NTRIPARLPDRTPVAHKTGSLD-GVVCDAGIIYGQHTD--VAVAFLXD +GESDSARTSIAIADTVATIW--- +>[subseq from] serine hydrolase n=1 Tax=Catellatospora sp. H14505 TaxID=1969805 RepID=UPI0011820BC7 +----TNRVADVFAGADMQGWLHARDLDTGREV-AVGAHDQVVIGSIFKILLVLEFARQAA +AGSLDPADRVLVRATDRLGGWGTAGCADDVEASLRDLAYFTMSVSDNTAADLLLCRI-GP +DLLPLLAQELGLTRTRLIGGPREILAVFDPAHTNSSTPEEVTRLLGLIWQDEAGPAQACA +TVRALMFRQLF-WTRLAAAFPPGVRVAGKTGTLP-GLHMEAGVAEYPDGGRYAVAVFAKT +ERLSMPELDLVLGRAAKLAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharothrix carnea TaxID=1280637 RepID=A0A2P8II60_9PSEU +-----ARVRAAFTDAGVTGRLHAVDLDQDREV-SVGADDPVVLASVFKVPLVVSLHHSTH +----DLTRRITLGQDRSTGPTGVGGMLDPVTMSLRDLAYLAITVSDNAAADALMDLV-GT +DDVNRTLRDLHLTRTVVVHRARDFMRALNPDHTNRGTARDLTTVLRHIWQHD-----DCA +PIRHTMARQVW-PHRLASGFPDDVRVAGKTGTLPT-IRNEVGVVEYPDGGRYAVAVFTRS +ASFTLPQADAVIGTAARLAVEH- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Candidatus Woesebacteria bacterium TaxID=2026804 RepID=A0A420Z6M5_9BACT +------SFKEKTKNLSGVYGFYVIRLNSGVSY-GVNERDIFEPASLNKLPVILAMYIKAE +KGDIDLETTYTLKDSDKVAGSGSLYGKPEGYLTYRELLKYMGKESDNTAANIARSIL-GE +EDIRQAISTIGMDNTVVIGE------------DQETTPYDIGLFFEKLWEGDIVSKKHRD +EILEYLTDTIY-EEWLAAGIPSDTDVAHKYGREVH-VVNDAGIIFTD--EPFILVLLSKG +IV--EREADQVFPELSRVIYR-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora pisi TaxID=589240 RepID=A0A495JFA6_9ACTN +------RLDAELADTAGTVSVYAGRLDAAPAY-TRLPDRTHYAASTMKVAVLGALYRAAD +TGTLDLDAPVPIENEDSAQDAPRFWARVGGHAPLRWLAHRMIVRSSNLATNLLLGHV-GL +PAVNAVWDLAGARHSHTGRGIEDFAA-RDAGIDNPVTAADLATLLGTIARGALATPATCA +AMLDVLLAQEH-REDLAAGLPAGTRVALKNGWVR-GVRHAAGVVFPDDAPPYALAVCTSH +HPEPDQTARRLIARVSATVWA-- +>[subseq from] Uncharacterized protein n=3 Tax=Fusobacterium TaxID=848 RepID=C6JN74_FUSVA +----EKRIREIINENSGVTGVIVRD-SFGKKI-MINEEVIFPSASIIKLFILMALNKD-- +----EYNKKIELKKEDKVGGCGILKVMEDGLLTIKDVAYLMICLSDNTATNILIDYI-GM +DKINESIKANGFRGTVLGRKMMDTEAR-KAGKDNFTTPEDVLKVLEILCGN------SD- +-DLDMLRNQAY-NNKIPLYYPREVDFAHKTGELMY-TEHDAGRLFFDNGW-VDIVVLTKD +LE-ENEDGIKINSLIGKLIFDNy +>[subseq from] Beta-lactamase class A n=1 Tax=Nocardioides albertanoniae TaxID=1175486 RepID=A0A543ACE5_9ACTN +----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD +RGLLSLDEPTPVHPDD--QQDPETWAAVGSSLPLGDLVRRSLIVSGNLAANLVLERV-GL +DQVADVLEEAEVTMTTVSRGIEDAPA-REAGLQNLVTANDMGKVLTKLASGRLLSPESTA +ELTGALVDQHY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIHPSEGDPQVMVVLTTG +LDD--DESEFRISEVARYLWS-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sutterella parvirubra YIT 11816 TaxID=762967 RepID=H3KI40_9BURK +------------------------------------------------------------ +------------------PHAPVLSKMNPDDISVKDAARAACSESDNRAANLLMKTLGSP +AAMTAWLQWKGDLRTRIDRYEPDCNKTSAYDVRDKTRPSAITQLWRKLYLD--FTPDERM +EWEDMLKANKHSAHLFKAQVPQGWTVADRTGSGSETNSSVHAMLFNPEGAAWFAAVHVRM +PATDLQTRDAVLAKACGIVM--- +>[subseq from] Beta-lactamase n=1 Tax=Saccharothrix sp. NRRL B-16348 TaxID=1415542 RepID=A0A0M8Y1M9_9PSEU +----------------------AVDLDHDREL-SVGADEPVVLASVFKVPLLVALHHSAH +----DLTRRITLDADRSTGPTGVGGMLDPVTMSLRDLAYLAVTVSDNAAADALADLI-GL +DAVNDTLRELGLTRTLVVHRARDFMRALDPDHTNRGTARDLTTLLRHVWRHDDC-----A +PIRRAMALQVW-PHRLASGFPDDVRVAGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRS +ASFTLPAADAVIGTAARLALEH- +>[subseq from] Beta-lactamase class A n=1 Tax=Aminicella lysinilytica TaxID=433323 RepID=A0A4R6Q610_9FIRM +-eELEEYLRDRTGSLAGHVGIYCQELATGKTM-DVAEEDVFESASVIKIWIMAAAYDLMA +KGKLSPDEILTLKDIDKVPD---EAMHPGLELTVEDTIRLMILISDNTATNMMIDLV-GL +DVVNNFLNKMGMSKSRLCRRLFDSDPS-GMGQENSISLSETGWFFRQLYDGTLVSAEASE +KMSSMMQNQQT-TYKIPFFLR-EIPIAHKTGEDC-GIANDVGIVFAKN--PFIFCFASNG +VD--VAAADRLCQDAALEVYNYy +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536JSW7_9CHLR +--ELVRQLDGLIGSFPGGAGIWVADPNIATPLyAHDPEEQVIAASLYKLGVLAEAERRVD +TGELHYNDIITIEPEDITADGSF--EDAGTQLTLDQALEVMITVSDNGTALALWHIL-GG +ANIDSTLQKAGVNNFHVA---------FDDTEDNWATPHAIGTFFTLLAKRQLISAGASD +RMLSRLERQQI-NDRLPAQLPPGVVIAHKTGNLG-GVMHDAGIVYTKTGPRVVVAMTWDA +PDE---DALNFISSLGSLVY--- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis alba DSM 44262 TaxID=1125972 RepID=A0A229R8F3_9PSEU +----IETINARAKETGVRVRLHAAEIDGTRRI-GIDETTPVVTASVFKLPVALELARQAA +DGGLDLGEPVTVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLIVARV-GK +AETEKTLRRLGFEHTTVPQDCGEVLGALQPEHTCATTAEEITRLLALIWRDEAASPTACA +DVRRWLELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] serine hydrolase n=1 Tax=Tsukamurella tyrosinosolvens TaxID=57704 RepID=UPI000DF69A2A +-------------------------------L-SVGGEQPVVPASVYKVVLLVAAARAVD +DGRLDPRARVLVDPATATPPTGIATLSDPVAMSVRDLLRSMVAVSDNAAAGVLMRLV-GL +EAVQATARDLGLRGTRIVGGDAEIHAAYDPTFGSATTAADMTALLAAVWSDAAASAEQCA +FARSALAGQVF-RHRVASGFGSAPSIAGKTGTLG-ALRNEVAVVAYPGEYPVAVAVFTHA +ARNDLPRVDAAIGTVAAIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Nocardioides sp. SB3-45 TaxID=2558918 RepID=UPI0012474F24 +---------------SGTVSVVLRVSGEEARL-AIDPEAQHYAASTMKLPVLVAALRRAE +RGELDLDRRVVVHDDSVVPGQRFTWAALGDAVALRDLVGRMVTVSGNLATDLVLEQV-GP +AEVATVLDLAGCSGTTLPRGIEDYPA-RDARLDNLVTADDLARVMVALAEGRLAGPAATA +ECERVLRAQTY-RGGIPAGLPPRLVIGNKTGWID-GVNHDVALVRAAGLPPVGLAVLVSA +PG-TPEEREAGIARVAAAAWD-- +>[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium AB60 TaxID=1230846 RepID=A0A5M8S8P4_9BACT +-rELEQQLQAIAAALHGKVALYAENLKTGQSA-GLAADEPVKTASTIKMAILLDAAEQIR +AGHASFGEKLVLSHENQVEGSGVLGELDTPLLTLRDTLTLMVVLSDNTATNMAIDRL-GL +ARINDTLKAAGLKQSYLYKKVYVPATDQPRFGLGKTTAREMAQIMARLAQGSAAGPGDCA +TILHMLRNQQ-DRDGIPRYLEHGSAIANKTGALD-ALRADVALIASKAG-PVVIAAYTYD +NANGDNEGQQTLGKLAKAVLERw +>[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. KQ-3 TaxID=2483800 RepID=A0A3M7TQY8_9BACI +--TLGHTVQTLSKKVKGDISLHIHT-E-EGEI-GYGSATPLIAASLIKVPCVYAAVLKSK +EGTFELDEETIVSAEQKIGGTGVLFHMPGEVITNRQLLSLMITVSDNTATNVIIDRI-GI +PYIQKTMVSAGCDSSWIKRKIIHTDPN-TQPLNNIMSARDFNRILMAINQGKNLTEENRE +FILSSLTGQQINHKLFSDGLPPTVRVAHKTGDDI-GMEHNGGMICLNGKTAYV-TVMTVK +LE-TNIEGQEYIRKVGKAVYNY- +>[subseq from] Beta-lactamase class A-like protein n=1 Tax=candidate division WWE3 bacterium GW2011_GWB1_42_6 TaxID=1619115 RepID=A0A0G1DTY5_9BACT +----EIQFAELTKKLPGVYGLYIKDVGSGREF-KYNDTTEFYAASLYKVPIGAAVLKEVE +AGKLNLDDTATYLPYDYSSGTGVIGTYSHGILKISDILSELLKNSDNTAQNILLRTL-SY +KNVQETFNEI-----VPDKNTSTYY------RYNLSTPAEIGYVFEKLYFGGYLNDADKK +YLADLMVNTSF-EDRISAYLKEGLIFSHKIGSWPD-SWHDCGVVYTETKSELIVCLMSQR +A---------------------- +>[subseq from] serine hydrolase n=1 Tax=Brachybacterium sp. EE-P12 TaxID=2306299 RepID=UPI000F0750B5 +----------------VRLAHCLLD-ADGTVLsAAHAEEPFYAASTIKLHVLLAVLRAAE +AGRVDLAAELPVTRTFTGAGQPFTPTHPAPGVAVRELAVRMIDRSSNEATDQLLELV-GL +DAVADVVRELGLTATRVERRIGDAA-ALSQGLTNETSAADLARTMHALVTGARLSEPSRE +LALAALAAQRI--PIIATALRDGVPWGSKSGWVD-GYRHDVAHVGAPGSDSRVLAVLTAG +LDAE-AADARIIAL--------- +>[subseq from] serine hydrolase n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=UPI000C1B86A7 +------------------------------------------------------------ +------------------------------------------------------------ +---NERLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK +FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK +DNKSDKPNDKLISETAKSVMKEf +>[subseq from] serine hydrolase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=UPI001143E1F0 +--RLTREVSDELEAAGLRARIVVRDLDSQAEI-SIAHDGPVPLASVVKVPIALAILNRIA +DGRLEADRQVHVAPGRFEGGSPMGTSRFRHPIAVDDLLMLSVCFSDNTATDALLDLV-PT +EEVQRDLDDLGLGGIQIRHHLDALVRQLDVSQANVATAAGLTDLLAELWRPERIQTSAAS +RLRELMAGNVVRHRLAPDLMSDAAKWSSKTGTLLH-LRHEIGVVEHSDGQTIAVVVLSES +SNAVQPAAEAALGAAARALH--- +>[subseq from] serine hydrolase n=1 Tax=Tsukamurella tyrosinosolvens TaxID=57704 RepID=UPI00079A9055 +-------------------------------L-SVGGEQPVVPASVYKVVLLVAAARAVD +DGRLDPRARVLVDPATATPPTGIATLSDPVVMSVRDLLRSMVAVSDNAAAGVLMRLV-GL +EAVQATARDLGLRGTRIVGGDAEIHAAYDPTFGSATTAADMTALLAAVWSDAAASAEQCA +FARSALAGQVF-RHRVASGFGSAPSIAGKTGTLG-ALRNEVAVVAYPGEYPVAVAVFTHA +ARNDLPRVDAAIGTVAAIAVD-- +>[subseq from] serine hydrolase n=1 Tax=Bacillus aciditolerans (strain JCM 32973 / CCTCC AB 2017280 / YN-1) TaxID=72581 RepID=UPI000EB0EF5F +-qELRKYLGELQNVTQCKFHIYFKVISSEIEF-QWNASDVIPSASTIKLPILLASLQRYY +-GDPSIKTKLFSIKDNWDSGTGVLRYLSKDNLPLMDLNTLMIIISDNVASNTIIDYL-GF +DVINETVQRFKLSKTKLFRKFDEINK-HAEAADNMTTAKEMGLLLEKIYLNSLNRDKICK +KAIEILKHQQV-KDRIPRYLPESVTALCKSGDYPD-GYHDIGIIEPANFYPYVLSAFSTN +CK-SKDIAVENIANISQFIYQQ- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFOXYB1_FULL_47_11 TaxID=1798401 RepID=A0A1F6BDF6_9BACT +---LKDVVDGALEGATGSYGIYIKNLKTGESY-VSGEHNVFDSASLYKLWVMAVVYQKIQ +DEQFTEDQVLREDVFVLNQIDPELAEKTEGVFSVREALRQMITVSDNYAALLLTEKI-GL +SSVATFLKENDLTESAVGTTG----------GPPTSTPYDIERFLEKLYREDVANPKYTA +EMIDLLKNQKL-NNGIPKYLPDASSVANKTGEIDR-FKHDAGIIYTDNGD-YSIVVMSES +AYP--PGAQERIARVSKAVFDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Tsukamurella tyrosinosolvens TaxID=57704 RepID=A0A1H5BWR7_TSUTY +-------------------------------L-SVGGEQPVVPASVYKVVLLVAAARAVD +DGRLDPRARVLVDPATATPPTGIATLSDPVAMSVRDLLRSMVAVSDNAAAGVLMRLV-GL +EAVQATARDLGLRGTRIVGGDAEIHAAYDPTFGSATTAADMTALLAAVWSDAAASAEQCA +FARSALAGQVF-RHRVASGFGSAPSIAGKTGTLG-ALRNEVAVVAYPGEYPVAVAVFTHA +ARNDLPRVDAAIGTVAAIAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535TKB8_9CHLR +--RLSADLALIAGTSGGRVGISLQELSGPRSL-SVNGGQSFVAASTYKLPLLMAEAQQIA +SGQARPSDLLCYAPGDAEDG-WFMDYQPGSCFTRDQLALRTGRYSDNTAAHILVRYLGGA +DALNRYAKSMGMTNSAL--WT-----------PNTTTPDDLSQALVSEALGRLGGAAAQA +WLYPILTHTAT-ERAIPAGLPAGVTVAHKTGSMP-GAENDAAYVRNG-RIAYVLSITVDG +LD--EGTAWSLMARISARVWQY- +>[subseq from] Serine hydrolase n=1 Tax=Kribbella antibiotica TaxID=190195 RepID=A0A4R4YJY9_9ACTN +---------------SGEFGVWLGRPDGTPVF-EHNAERTHYSASTMKLPVAMAMLRKVA +AGELSLDQPIAVHNDFASQEAPETWTKLGTKVPLGWLATEMITLSSNLATNLVLEQV-GI +DAAQAVLAEYGDGASAIRRGIDDRAA-QAAGISNEMSPAGLAGVLVAV---------DNQ +YLRDLLAGNQW-NGELPALLPPGTRVEHKNGWDRR-IRHDGGIVRPPDADPFVLVVCTTS +ELPD-ARAQQLIAEIALEAWN-- +>[subseq from] Uncharacterized protein n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A644Z322_9ZZZZ +--------------LDGTVSYYYRAFDKGEAA-CCNMDAPHDAASIIKLPIMVEAIRQFE +SGEAARDEVIRIRDADRVPPCGVLTFHEGLPVQLIDLVWLMVTLSDNMAANLLMDRL-TL +PAIRREMMALGMTGCRLNRKLFA------PGPGNIITCRDICMLFEQLYAGTLVSAAASH +EMLDMLTGQQL-QNKIPMLLPLDMRIAHKTGEDE-GTSHDVGIVYAK--KPFLVGFFGTG +VD--APSFNRT------------ +>[subseq from] serine hydrolase n=1 Tax=Fodinicola sp. GKU 173 TaxID=2681555 RepID=UPI0013D4F5B1 +----DEELTELFLAANCTGTVSAVALDGSGEA-GFGADEPMVAGSVIKICVALEAERQFA +DGRLDPARRVRLTAADRTPGTVGFSLFQDDIVSLRDLVAPMLTISDNVATDALVRAA-GL +DSINASLRKLGLTETVMTGDIRTVIDELRPATATRTTAREMTTLLRLIWTDQAGPAAACR +RVRELMAKQLT-KNRLASGFPYPATVSAKSGGLAGTVRNEAGVVEFPDGRTYAVAVFTRT +ERDGETPMNHAIGQAAALAV--- +>[subseq from] PEGA domain-containing protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536KQM2_9CHLR +-------LNAYLGGLGGRYGVWLDDLSSGRQI-GYHAGDSMEAASVIKLPLALYLLDQAA +QNKLKLSDTIQLEDSDFMGGTGTLYYAPGDTLSYQDLLGLLIQQSDNTAWKALKRVL-GS +DKVDAYAASIGAPDC---------HQ-----EDDNCTPQEAGLMLAKLATSAVLDAGGRQ +MLIGLLENTAF-NDRINYYLG-NVAIAHKVGMDG-GVMNDAGIVLGSHQ--FVISMFTDS +DNPD--QGVQAIRDVSRAAAKYy +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Woesebacteria bacterium RIFCSPHIGHO2_12_FULL_46_16 TaxID=1802513 RepID=A0A1F8B053_9BACT +-kKAKEKFKEVTKDLSGLYSFLIIDLEKDISY-GTAETNTMQAASLIKLPTLAALYLEAE +KGNIDLEAKYTLKQSDKLPGAGSLSGKPAGTLTYRDLARLMGKQSDNTAFGIVRRLL-GD +EKINQVTAEIGMTKTSLA--------------ENTTTPQDIGLFFKKLWKKEIVSDDSRD +EILGFITDTIY-ENWIVAGVPDDIRVAHKYGRELH-VVNDAGIVFSK--YPFVLVVMSDG +VV--EREADEVIPKIAERL---- +>[subseq from] serine hydrolase n=1 Tax=Haladaptatus cibarius TaxID=453847 RepID=UPI000678709E +---------CYADRIDGELGVFLYGPDEFDTVyTRNARRAFRSASVVKILILYALYERYD +GRLDSLAESCPLAPENRVGGSGILH-LLDATPTIEELARAMIATSDNAATNQLIDHL-SM +TTINDSAAKLGMKHTRLARKMMTTLEVPEDEPANVTSPVDCARFFADIGCEATLSANAYE +RLCVPLSAQKD-TSMVPRYLPYETEIMHKTGWLPT-AALDAGLLSVPDEPPLVFSVFVDS +VSHG-ADAADAIAEIGDAVF--- +>[subseq from] Serine hydrolase n=1 Tax=Peptococcaceae bacterium TaxID=2052179 RepID=A0A3B9M2Y0_9FIRM +-rALEQQINNYLASQPGVYGVYFEDLYTGRSF-GIKADDAFPAASTVKFPTVLFINKLVS +QGILDWQQKLTYNAAQHYQGSGILQFGIKDGLTLRSLTTQAITTSDNIAYNMLRDFV-GK +GSVANFMKEIGGTTVYP------------N-GNNWITPRDMGTYLKV-ALNWSQTDSNTA +RLLDDMANGIY-NEGIPLYLPDMVKVAHKEGFIW-GCPSDVGIVYG--KRPFIIVVYAYN +VE-DPDQGFANIATISRMIYDY- +>[subseq from] Cell wall-binding protein YocH n=2 Tax=Moorella thermoacetica TaxID=1525 RepID=A0A5B7YPR5_MOOTH +-tSLQQQIQNYLADKPGTYGIYFKDLASGQSF-GINADTPLPAASTVKLPAVLFINSLVD +QGVLDWQQKLTYNSADYQGGSGILQFSVKDGFTLRTLTTLAITASDNIAYNMLRNFV-GK +GSIANYMQSLGGQTV------------FPG-GQNLSTARDMAIYVQAALNSAN-TSANGR +RLLDDMANGIY-NEGIPLKIPAGVTVAHKEGFVW-GSPGDVGVVFG--SRPFIITVLSQN +VP-DPDQGFANIATITRMIYDY- +>[subseq from] serine hydrolase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI00048E9997 +-----------LDRVPGTVSAYLARLDTAPTW-IRHPATTHYAASTMKVAVLVALYRALE +AGRLASDTAVPVRNEFDSAQPGAAWDRLGDTAPLRWLAERMIVRSSNLATNLLLDQV-GL +PAVADVWARAGARHSVTGRGIEDFAA-RAGGITNLITAADLAALLRDLALGALATPESCT +AMLELLVAQEH-REDLAVGLPAGARIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCTTG +DDPDHSPDEDACQLIADISAR-- +>[subseq from] serine hydrolase n=1 Tax=Kribbella sp. YM55 TaxID=1572660 RepID=UPI0010397248 +----KARIRGIFEDAGVRGWLHAVSLDDGASV-ELDADVVVPLASVYKLPLLAGFSRLVD +LGELDPREQVTLEPSSRTAGPTGLSMFADPVVSLRDLALSMATVSDNAAADALLDIV-GL +RRLAAILESFGLRRTWVRRGTAANLRVYEAANGSAASARDLTLLLRQLWAGELLSAEQTE +FVKATMHRQIF-LQRVASGFPDGVRIAGKTGTFG-ALRHEAAVVTLPDGAAFAIAILTLA +ARGDQPRVEAAIGEAARVAVD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004C98F01 +---VAEAIAADWAAVGVRGSFLARNLDTGEQL-GFDADEPVPLASVAKVPLALVVLDRVA +AGELDPARPVTVDPRTSSVPTGLAAFRHPATVAVGDLLLLMLSVSDNAAADALFDLV-PT +AETDARLRAWGCDGIRVRHRMNHLYETLDPAHANAGTAAALVGLLQRVWRDEISTPSATA +ELRRLMGHQVF-TQRLAGELRADLRWSGKTGTFLH-LRHEIGVVEADSGDRVAMAALTRA +TRRAAPDIDQAIGAAGRDAF--- +>[subseq from] serine hydrolase n=1 Tax=Kocuria sediminis TaxID=1038857 RepID=UPI0012E12FEF +------------------------------------------------------------ +-----------------------TDTVPGTTFTVREAVERMITWSDNVSGAALGRWL-GW +HEVQVFAQGQGFESTTYDPDTGEARTV-----AMTTTPDDVADLLDRLRGGELLSGPSTT +LLLGFLAAQQL-DYALSTGLSPDVEFAHKTGLLIQ-VSHDAGLVRLNGK-EYVVAVLTDG +WSG-------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Terriglobus roseus (strain DSM 18391 / NRRL B-41598 / KBS 63) TaxID=926566 RepID=I3ZHL4_TERRK +---PDEAVKQVIAQHHGSVALYAHQLNTGKTI-SIDADKPVQTASTIKLALLWTAVHEIA +LGHATWDEKVTLKPGEGVAGSGILHFFDTPILTLKDIATMMVIVSDNTATNLMIDRF-PT +KQVDGNMTALGYTDTWLYKKVFKPADDQPKFGLGKTTPHQIAQLIEKIGRCDAKADTACN +VAIDMLRNQF-YRDTIPRYLEKGSGIASKTGSLD-ATRSDVAILAAKSG-PIVLAVYTYD +NADKDNEGEVAIAKIAQAVVKAw +>[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00037650C4 +----------HLDRIPGTVSAYLARLDAAPTW-TRHPDTTHYAASTMKVAVLVALYRALE +AERLAPDTAVPVHNEFDSAQPGAAWDRLGGTASLRWLAERMIVRSSNLATNLLLDQV-GL +PAVADVWARAGARRSSTGRGIEDFAAR-AAGITNLVTAADLAALLRDLALGALATPESCA +AMLDLLVAQEH-RVDLAAGLPAGTRIAHKNGWVR-GVRHSGGVVYPDDAPPYVLAVCHTD +EHSDDTDACQLLADVSAHAF--- +>[subseq from] Beta-lactamase class A n=1 Tax=Brachybacterium sp. AG952 TaxID=2183989 RepID=A0A4R6QX67_9MICO +--------------TEVRLAHCLLD-ADGAVLsASRADDPFYAASTIKLHVLLAVLRAAE +QGELDLDAELPATCTFTGAGEEFTPTHPEPGIALRDLATRMIDRSSNEATDQLLELV-GL +DAVAAVVGELGLGATRVERLIGDAS-ALERGLTNETSAADLARTMHHLVAGPGLSDDSHE +LALAALHAQTI--PIIATVLRDGVRWGSKSGWVD-GYRHDVAYVEDPAGGRRILAVMTAG +LAED-EADARITALAA------- +>[subseq from] Uncharacterized protein n=3 Tax=Firmicutes TaxID=1239 RepID=A0A3C0LY65_9FIRM +------------------------------------------------------------ +--------------------------------TTKHLLDEMITVSDNSATNELVRYLNGM +KKVNAFIKAQGFEYTHEYNGLEDTSLWYDADTKNTTSAKDCGRLLERIYRGEFISHLASR +QMEELLLNQQV-TYKIPSTIPSESRVANKTGETSD-CENDAAIVYTPKGD-YILCIMSCE +VS-SKSSAVDSLQEMSSLIYSYf +>[subseq from] Beta-lactamase class A n=1 Tax=Tamaricihabitans halophyticus TaxID=1262583 RepID=A0A4R2QXM4_9PSEU +------EIIARAEEVGVSVWMHARAIDGTASL-GIDATTPVVLASVFKVPLAVELANQAE +RGRCDLAEQVTVPAGPKVAYGLATFQHPA-TLSLDALATLMIGISDNVATDVVFARI-GK +RAVRELCDRLGLADTAIEQDCAELLGALRPEQTCRSTALDMTALLSMIWRDEAAGPAACA +NVRRWLGLQVW-PHRLRSGFHDEVRISGKTGTLPT-IRNEVGVVEYANGERFAVAVFTEA +IDAQAPERDGFIGFAAARAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Phycisphaeraceae bacterium TaxID=2026777 RepID=A0A2D5Z900_9BACT +-----DALDRLARAFPGRVGIYIEEVAGGARY-AFAADERFPTASVFKIPVLLTLYQLAE +AGRLSLDDRHRVAADISTHGTGILKQFTDAPLSLRDHCRIMISHSDNIATDTIIRAV-GL +DQINAMLERQGLANTRVPMEIGRWHYAFSDRLENVASPRDLAALVGRIDQGKLAGAAATE +SMRQMLR---LGDGPITSVLQPNAQTMSKRGSSRR-IVCDVALVPLAAG-PLVISVMTLE +DQ-PRKSGTALIGEVTRLAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Kocuria polaris TaxID=136273 RepID=A0A0A6VV09_9MICC +---LAADLEELAAEVPGELGVVLLDPEGGEVV-ARNADRPFTSASLYKLFLAHAVLDRAD +RGALALSDVV-----------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW +GQVEAFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGSSTA +LLMGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG +WS-DYEESAPWFGDAGR------ +>[subseq from] Uncharacterized protein n=1 Tax=Kocuria sp. CNJ-770 TaxID=1904964 RepID=A0A1Q9SNK1_9MICC +------------------------------------------------------------ +-----------------------TDTVPGTTFTVREAVERMITWSDNVSGAALGRWL-GW +HEVQAFAQWQGFESTTYDPDTGEAG-----TVAMTTTPDDVADFLDRLRTGELLSEPSTT +LLLGFLAAQQL-DYALSTGLSPDVEFAHKTGLLIQ-VSHDAGLVRLNGR-EYVVAVLTDG +WSG-------------------- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Candidatus Omnitrophica bacterium CG11_big_fil_rev_8_21_14_0_20_43_6 TaxID=1974747 RepID=A0A2H0LNZ8_9BACT +------------------------------------------------------------ +--------------------------RAG-VFTVEELIGLMIYDSDNTATNILTNLV-GI +DYLNLVFIRLGLKDTNLSRKIADFKTR-DRGVENYTTAQDIAGLLEQIYRRKLISRDLSD +KCLRILKLQRV-NDRIPKYLPADVMVAHKTGLERN-VCHDAGIIFDQEGD-LLICVLTKH +NNPNAQASKNFIARVALHTYR-- +>[subseq from] Serine hydrolase n=1 Tax=Tsukamurella asaccharolytica TaxID=2592067 RepID=A0A5C5RC41_9ACTN +-----------------------------ATL-SVGGEQPVVPASVYKVVLLVAAGRAVD +EGRLDPRARVLVDPAAATPPTGIATLSDPVEMSVRDLLRSMIAVSDNAAAGELMRMV-GL +DAVQKVVHDLGLRGTRIVGGDAEIHAAYDPTFGSATTAADMTALLAAVWSDAAASAAQCA +FARAALAGQVF-RHRIASGFGSAPSIAGKTGTLG-ALRNEVAVVAYPGEHPVAVAVFTHA +ARNDLPRVDAAIGTVAALAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. HM5-17 TaxID=2487710 RepID=A0A3N2P8Z1_9ACTN +------------AATPGTVSVYVGRPGIRPAY-TRLPESPHYAASTMKVAVLAALYRAAE +AGTIDLDAPVPVVNDFPSAGGGRFWARLGGTATLRWLAERMIIRSSNLATNLVLGHV-GL +PTVAAVWADSGARHSRTARGIEDFAA-RDAGLDNQVTAADLAGLFCAITRSRLAQPGTCS +AMLDVLFRQER-GEDLAAGLPAGVRIAHKNGWVR-GVRHGAGMVFPDDAPPYAIVVCTSA +AAGDDEAACRLIARISAMAWE-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. NEAU-HG-1 TaxID=2697657 RepID=UPI001379006E +-----------------------------REV-AVRADEQVVIASVFKILLVLEFARQAS +VGQLDPTERVLVRAADRLGGWGVAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GR +DVLPMLAAELGLPRTRIVGGPRELVEVLDPAHTTSSTAREMTRLLGLIWRDEAGPAPACA +AVRELMDRQLF-WTRLASGFPPGVRVRAKTGTLP-GLHLEAGVAEYPDGRRYAMAVFART +ERTRRIDVDLAMGEAARIAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=A0A3D4RBK0_9FIRM +------------------------------------------------------------ +--------------------------------TTKHLLDEMITVSDNSATNELVRYLNGM +KKVNAFIKAQGFEYTHEYNGLEDTSLWYDTDTKNTTSAKDCGRLLERIYRGEFVSHLASR +QMEELLLNQQV-TYKIPSTIPSESRVANKTGETSD-CENDAAIVYTPKGD-YILCIMSCE +VS-SKSSAVDSLQEMSSLIYSYf +>[subseq from] Serine hydrolase n=1 Tax=Brachybacterium sp. HMSC06H03 TaxID=1581127 RepID=A0A1F1XJX3_9MICO +--------------TEVRLAHCLLD-ADGAVLsSERAEESFYAASTIKLHVLLAVLRAAE +QGELDLDTELPATRTFTGAGEEFTPTHPEPGIALRDLATRMIDRSSNEATDQLLELV-GL +DAVAAVVGELGLTATRVERLIGDAA-ALERGLTNETSAADLARTMHHLVAGPRLSGDSHE +LALAAMHAQTI--PIIGSVLRDGVRWGSKSGWVD-GYRHDVAYVEDPVGGLRVLAVMTAG +LAE--EEADARIAAL-------- +>[subseq from] Serine hydrolase n=1 Tax=Arthrobacter sp. MYb23 TaxID=1848603 RepID=A0A2S9DAD8_9MICC +--DITDQIRAIFAEADVTGSLHARAIAPGAGEiSVGADEPVVLASVFKIPVVLAFARAVQ +EGRVDPLERVLVGPKYRVGGIGAGGCRQDVEMSLGDLALFMLTLSDNAATDLILERV-GV +DAISTLLDELELLETHIGGGCLALWDLDPRKSLHRSTPREITTLLSSIWAGHP--DTPAN +QMIRSMMAEQVWTHRLSSGFDDSAIVAGKTGTLPT-VRNEAGVVTLPDGSSYAVAVFLRS +QSDRQPRADAAIGHAAYLAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Kocuria turfanensis TaxID=388357 RepID=A0A512IGS1_9MICC +------------------------------------------------------------ +-----------------------TDTVPGTAFTVREAVERMVTWSDNVSGAALGRWL-GW +HEVQAFAQGQGFESTTYDPDTGEAG-----TVAMTTTPNDVADLLDRLRGGELLSGPSTT +LLLGFLAAQEL-DYALSTGLSPDVEFAHKTGLLIQ-VSHDAGLVRLNGK-EYVVAVLTDG +WSG-------------------- +>[subseq from] Serine hydrolase (Fragment) n=2 Tax=Kocuria rosea TaxID=1275 RepID=A0A4S3PQU8_KOCRO +---LAADLEELAAEVPGELGVVLLGPEGGEVV-ARNADRPFTSASLYKLFLAHAVLDRAD +RGALALSDVV-----------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW +EQVEAFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGSSTA +LLMGFLEEQHF-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG +WS-DYEESAPWFGDAGR------ +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Caulobacter TaxID=2648921 RepID=A0A0Q6U0P8_9CAUL +--RLQGRIEAIAARAPATLGVAVEDLTTRQLW-TFNGDQAFPLGPAARVPILAAMMAEAA +AGRLPPGELVTVRDVDLSPPSAVADAWPGRQWSVADLETLAL-HGDTTALDLLTKRIGGP +GAVNGWLDVQRIEGVSVDRYRRQIATARQGDARDTATPVAMARLLEAFAFRELGLAPDFD +GLLGH------DAGYLALALPKGARLAQAAGSARTPGSQALAVVELKDGRRIAFVIFLTG +SAADAAKREALITDVGRAVLEEf +>[subseq from] Serine hydrolase n=2 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536BEF5_9CHLR +-dQLRSDLEAIARASGGRVGISLEELSGPRNL-SINGEQSFGAASTYKLVLLMAEAQQIA +SGQGRDSDLLCYAASDAEDG-WFMDYQPGSCYTRGELARRTGRYSDNTAAHILVRYLGGP +DALNRYAKSIGMNRSAL--WVP-----------NTTTPDDLSQAFVSEALGQLGGAAAQG +WLYPILTHTAT-EQGVPAGLPAGSTVVHKTGTMT-GTENDAAYVRNG-RIAYVLSVTVDG +LD--EGTAWSLVARVSARIWQY- +>[subseq from] serine hydrolase n=1 Tax=Tsukamurella tyrosinosolvens TaxID=57704 RepID=UPI000C7EDF81 +-------------------------------L-SVGGEQPVVPASVYKVVLLVAAARAVD +GGRLDPRARVLVDPATATPPTGIATLSDPVAMSVRDLLRSMVAVSDNAAAGVLMRLV-GL +EAVQATARDLGLRGTRIVGGDAEIHAAYDPTFGSATTAADMTALLAAVWSDAAASAEQCA +FARSALAGQVF-RHRVASGFGSAPSIAGKTGTLG-ALRNEVAVVAYPGEYPVAVAVFTHA +ARNDLPRVDAAIGTVAAIAVD-- +>[subseq from] Uncharacterized protein n=1 Tax=bacterium UBP9_UBA11836 TaxID=2060920 RepID=A0A355TUT6_9BACT +----------------------------------ENLDKQFRAASTIKIPIVAALFYEAM +HKRLNLADLVAISEADIVEGGILCEVGVGRHFSWRELARLAIVISDNSASNLIIKKL-GF +TFINSFIKDLQAHHTVLNRYFMASPQ---EMGENYTTARDLALIMASLWQGRILDKSYND +EFWAILSRQQF-IEKLPSRILGQVKSYNKTGELDDGARHDAAVFTYKSHA-WGLVALTDQ +QKLPAWQIDWAMGAWSELI---- +>[subseq from] serine hydrolase n=1 Tax=Sciscionella sp. SE31 TaxID=1445613 RepID=UPI0004DF50F1 +----AESVATAWQRIGTSGSFLARELHTGREL-GFDVDTALPLASVVKVPIALVALDRIA +EGTLDPAQPVTIDPADKSVPTGVSAFRYPATLAIADLVHQMLTVSDNASADTVLDLL-GL +DAVEERLREWDCAGITVRHRMNRMYEPLDPAHANLGSAAALVDLLERVWLDRIARPEATA +ELRRIMGAQVF-TQRLSADLRDSVRVSGKTGTYLH-LRHEIGVVETDSGDRIAIAALTRT +DRRAAPDVDLAIGAAARAAFE-- +>[subseq from] Beta-lactamase (Fragment) n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q5VRV6_9BURK +-dALRQEVERIDRASPGTLGVYVKRLDDGTTL-DYGGDRKWYLGSTVKVAVAITVLQQVD +AGQMKLGDTLVLQETDRIEAGPLVRQKVGSRLTVDELLRRMLGDSDNTAANMLIRAV-GE +ERLNATAKAMGDGAM--------------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Clostridium sp. BNL1100 TaxID=755731 RepID=H2JBD9_9CLOT +---LKKLITDYTAGLSGKYGVTFIDLATGEMV-NVNDTDRYIAASTSKLPINVLLYKNVE +AGKVNLDDMLTYQKEDVEPGTGIIQKSAGTQYTVRETSKLAIRKSDNCGVNMLIRLL-DI +QNVRQYLVDLGGKVY--------------YDNRHRSCPYDMALVAQDLYKHYLKNQDVYG +ELINNLENTDW-HDRIDAQLT-GVKVAHKIGNQVK-TANDVGIVFAS--HPYVLSIMTDN +VD--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Prauserella sp. PE36 TaxID=1504709 RepID=A0A365Z6P9_9PSEU +----AESIAEHWREVGATGHLLARNLDTGEHL-GFDVDTPVPLASVAKVPLALVVLDRIA +EGDLDPALAITIDPATKSLPSGVAAFRYPATLAVGDLLHLTLTVSDNASADALFDLV-GV +EHVDRRLRDWGCTGIRIRHRMHRMYETLDPAHANVGSATALVELLQRCWLDEVSRPDATA +ELRRLMALQVF-NQRLSSDLRADVRVSGKTGTFLH-LRHEIGVVTAESGDRVAIAALTRS +ARRAAHDIDLAIGAAARSAF--- +>[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E3MXT9_9PLAN +--ELPRQIELLENKHAGTFSIEVQRLDADEHF-ALRAKTPLPTASTCKLFVLCELFRQAE +EGTIDLRAPISWKPEFHRGGDGVLRAMTGQELSIHNMAVLMIIVSDNIATATLVDLV-GP +DNVNRTMKSWGLAATNVYDGLPGGSNA-SRMKQPVSTAHDLCSLMTRIYRHDVLTPKSCD +EIIRIMRAQRC-NDMLPRYIPAKSWIANKTGYGA--CRVEVGVVRTTEV-TFSLAMFFKP +HQP-------------------- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A519GLY7_9BURK +-------------------------------------------------PVAIAVLRGIE +RNQFSLDSNVTLRASDYVDGAGPTKGYPVGTLTVRFLLEQMMVLSDNTATDMLIDLV-GI +SEVNAVTQSLVPEGFSDITTLSDVRRAYYAQGVNSARLDAYGELLARLVEGQALTPRWTA +YLIALMERVQTGTHRLKAGLPGGLRFAHKTGTQRY-RICDAGLIRTAAHQRRVLLVACTR +GDVPVERSEAALMQVGAAL---- +>[subseq from] Serine hydrolase n=1 Tax=Gordonia sp. i37 TaxID=1961707 RepID=A0A1V4PTD9_9ACTN +----ARNVAAIFADAGCAGWVHARVIGASQEI-DLGADHPVVMASVYKLTLAIAFAREVD +AGEIDASEQVLVDPRARPDGPTGLSLFGDPVLTWRDLVTSMMVVSDNAAADVVLERV-GL +ESIAAVLADAHTTHTTVVDGVRQVHAAYDAAYTSATTPRDCTRLLDCLWRDVLATPESSA +WIRRLMAQQVS-RSRIASGFSVGTRVCGKTGTIGP-IRNEVAVIEHPEEYTIAVAVFTRS +ARGDGPRVDVAIGAVARAVVT-- +>[subseq from] Beta-lactamase n=2 Tax=Candidatus Amesbacteria TaxID=1752730 RepID=A0A0G1UHV9_9BACT +-kEIADKLRKRVEGLSGEYAVGVYRLKTGENY-GFNQRVEMPAASIMKVPIMTAVLREAE +AGSLKLEDTYILKETDKRYGSGPLELLKAGTVTVERMLSVMGKNSDNTAPVVLARMI-GW +DKVTETLEKLGMTNSDFE--------------MNTTTAEDVVEMWAKLYEGGIVAQDHRE +MMWEWLTESIY-EERIPAGVPEWVHVVHKVGTDA-GVWADAGIVECK------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora krabiensis TaxID=307121 RepID=A0A1C3N544_9ACTN +----------------------------GPEV-AIRADEQVVIASIFKILLVLEFARQVV +AGQVDPGERVLVTAADRLGGWGLAGCADDTEVSLRDLAYFAMSVSDNTAADVLLRRV-GA +DLLPMLAAELGLARTRVLGGPRELVEVFDPAQTTSSTAREITRLLGLIWRDAAGPAPACA +MVRAWMARQLF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGRRYAIAVFARS +NETRRIDVDLAMGEAARTAV--- +>[subseq from] serine hydrolase n=1 Tax=Kocuria turfanensis TaxID=388357 RepID=UPI0009FD9B0A +------------------------------------------------------------ +------------------------DTVPGTAFTVREAVERMVTWSDNVSGAALGRWL-GW +HEVQAFAQGQGFESTTYDPDTGEAG-----TVAMTTTPNDVADLLDRLRGGELLSGPSTT +LLLGFLAAQEL-DYALSTGLSPDVEFAHKTGLLIQ-VSHDAGLVRLNGK-EYVVAVLTDG +WSG-------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Weissella sp. 26KH-42 TaxID=2506420 RepID=A0A4P6YSP5_9LACT +-------------------------------------------ASTIKVFILAALLDQES +KGHIKLTQTYQLQASDKVGGTGILQGAASGSYSYKELANLMITQSDNTATNIIIQRLGGF +SVVNNYVQSLGYRHTKLQRKMMDLTN----QKNNMVAANEACDFLYKLYQGQLVDEQARQ +WFLQLMTQTTN-RQKFAAQGNNGITSYNKSGESSQGIQNDLAIVTRGKQA-YVVAGL--- +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Prauserella sp. YIM 121212 TaxID=1477506 RepID=A0A318LXM6_9PSEU +----AESIAEHWREVGATGHLLARNLDTGEQL-GFDVDTPVPLASVAKVPLALVVLDRIA +EGELDPALPITIDPATKSVPSGVAAFRYPATLAVGDLLHLTLTVSDNASADALFDLV-GV +EHVDGRLRDWGCAGIRIRHRMQRMYETLDPAHANVGSATALVELLQRCWLDQVSRPGATA +ELRRLMALQVF-NQRLSSDLRADVRVSGKTGTFLH-LRHEIGVVTAESGDRVAIAALTRS +SRRAAHDIDLAIGAAARSAF--- +>[subseq from] Beta-lactamase class A n=1 Tax=Trichococcus patagoniensis TaxID=382641 RepID=A0A2T5IDV1_9LACT +------------------------------------------------------------ +--------------------------QMADGATVADYLTSTITVSDNETAKELAYLI-GW +DNIEAFIHEQGFVSTNFHPYLESDGVYYNGDL--ETTPAEVAFLLERLLDGDLLSESSTA +YFLGLLADQQL-VYALNTGLDEGVTFAHKTGLLDY-VSHDAGILTLDGQ-TYIVAILTDG +WQDATNDATPVFESLGSAVMTY- +>[subseq from] Uncharacterized protein n=1 Tax=Kitasatospora sp. CB01950 TaxID=1703930 RepID=A0A1Q5EC63_9ACTN +------DLREIFERAGCEGALCVREVAGDGEI-VLDADRAMVSASVFKVQIALEMESAFV +DGRLDGRERVVLGAAERTFGPVGTSLFEDEVLSWRDLVVLMLTISDNPATDALLGRV-GV +DAVNATAARLGLSGTFVESDLRTMLDAMDPARGTRTTPRDMAELLRLIWTDGAGPAAACA +RVRKVMASQLT-RHRIASGFRPPVRVAAKSGSLLGVVRNEIGVVSFPDGRQYAAAVLTRS +PLSDDAAINRAIGEAARQAV--- +>[subseq from] Uncharacterized protein n=1 Tax=candidate division WWE3 bacterium TaxID=2053526 RepID=A0A3D0ZQB5_9BACT +--KTETQFSELTKKLPGVYGLYIKDVGSGREF-KYNDTTEFYAASLYKVPIGAAVLKEVE +AGKLNLDDTATYLPYDYSSGTGVIGTYSHGILKISDILSELLKNSDNTAQNILLRTL-SY +KNVQETFNEI-----VPDKNTSTYY------RYNLSTPAEIGYVFEKLYFGGYLNDADKK +YLSDLMVHTSF-EDRISAYLREDLIFSHKIGSWPD-SWHDCGVVYTETKSELIVCLMSQR +A---------------------- +>[subseq from] serine hydrolase n=1 Tax=Kocuria rosea TaxID=1275 RepID=UPI0011A3837D +---LAADLEELAAGVPGELGVVLLDPEGGEVV-ARNADRPFTSASLYKLFLAHAVLDRAD +RGALALSDVV-----------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW +EQVETFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSTA +LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG +WS-DYEESAPWFGDAGR------ +>[subseq from] serine hydrolase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI00048D14C6 +-----------LDRVPGTVSAYLARLDAAAPTwIRHPATTHYAASTMKVAVLVALYRALE +AGRLASDTAVPVRNEFDSAQPGAAWDRLGDTAPLRWLAERMIVRSSNLATNLLLDQV-GL +PAVADVWARAGARHSVTGRGIEDFAA-RAGGITNLITAADLAALLRDLALGALATPESCT +AMLELLVAQEH-REDLAVGLPAGARIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCTTG +DDPDHSPDEDACQLIADISAR-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. NBS 11-29 TaxID=1960879 RepID=UPI000B7862C1 +------------DRAAGIVSGYVGRLGARPTW-SRRADATHYAASTMKVAVLVALHRAAE +AGRLDLDAPVPVRNSFDSALPGATWDAVGGTAPLRWLAERMIVRSSNLATNLCIGQV-GL +PAVAQAWTLAGARHSVTGRGIEDFAA-RDAGIDNLVTAADLAALLGGLALGALASPAGCA +AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPADAPPYAIVVCTTT +DPADDDDACRLIADVSARVWA-- +>[subseq from] Serine hydrolase n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A357NIE0_9FIRM +------------------------------------------------------------ +----------------------------------PALVSDMIIYSNNEAFWELAEQL-GS +PTLETTCRDLGLRNTAIHNDAAYQR----TGYHSITTPRDMGKALEGLLRGRYIGNKNSK +TVLRLMENGVY-NEEIPRRLPPNTPVAHKPGELDD-ILCDVGIVFNAQR-PYLISVYTKS +NAGS-TAASNMIADIAAITDKYf +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharothrix variisporea TaxID=543527 RepID=A0A495XGC4_9PSEU +-----ARIRAAFADAGVTGRLHAVDLADPTRQvAVGADEPVVLASVFKLPLLVALYRS-- +--GIDLTRRVTLDPGDRSTPTGIGGLLDPVTMSLRDLAFLAITVSDNAAADALVDVV-GL +DEVNRVLRDLGLTRTAVVHRARDFMRALDPTRTNRGTAREMTSLLTHVFAEDVYEPIRRA +M-----SLQV-WPHRLASGFPDDVRVAGKTGTLPT-VRNEVGVVSYPDGGRYAVAVFTRS +ASFTLPAADAVIGTAARLAVEH- +>[subseq from] Serine hydrolase n=1 Tax=Streptacidiphilus sp. DSM 106435 TaxID=2126346 RepID=A0A345SRK2_9ACTN +-----------SAALPLTLAVAAVDVDGGRTV-GVDDTAVLPVASASKLLLLAEVSRRLD +SGELRADQVVDIPDQDVAGGTGLLRRLGRRGWTVEDLAWLTASVSDNTATNALLRLV-GR +PATARLARQLGLDHLTLHDSVRDVRGPDVPPVFATGTARDLARLVALTVRGTMASPAASG +RLLEWMRSNTDYAPCFPDPLPGGLLVANKTGTDT-GVRADAGVIIGARRVAYAVVAHWDV +ALSTERAAVHAIRDVGRTL---- +>[subseq from] Beta-lactamase class A n=1 Tax=Xiangella phaseoli TaxID=1144548 RepID=A0A1H7D8P5_9ACTN +-----DDLHARLDRAPGTISVYAGPLDAPPTW-VRHADATHYAASTMKLAVLAALHRAAE +AGHLDPDTPVEVVNRFTSAHAPPYWERLGERATLRWLAERMVVRSSNLATNLVIEHV-GR +PAVAQVWASAGARHSVTARGIEDFAAR-QAGITNLVTAADLAALLDAVATGAIASPASCA +AMLDVLCAQQI-RQDIAEGLPAGTRLAHKNGWVR-GVRHGAAVVFPDDAEPYLLVVCTTT +TLDDDQASEPADAAARRLVAD-- +>[subseq from] serine hydrolase n=1 Tax=Veillonella magna TaxID=464322 RepID=UPI0003F520DD +---LQTELDDIIKEYQATISYMVTIHNDDEYVvARNEDTVHASASMIKILIMLSVFEAVS +QQKLALTDQIALTATPRVEGGGALQELQGNHFSVLELCRLMMVLSDNWATNLLIRTL-GM +TFINDTAKKYGAAKTSLKRYMMDTAAA-ARGEENVTTAYDMIVLLDAIFQIREQS-VGGH +EMWQILGRQQF-RDKLPFHWGEEVPFHHKTGCLDR-VEHDGGILPLMNGN-FGLVVLISN +MDND--EAIQLTARMGR------ +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium RIFCSPLOWO2_01_FULL_36_13 TaxID=1798614 RepID=A0A1F6JL09_9BACT +---LSKIVEKNLENQGGSYAVGILNLTTGDEY-FKNKHQIFDTASLYKLWVMGLIYQKIE +NGTLQKNTVLSDSVENLNKASESAERKEGEVMSVENAIDLMITKSDNYSALLLSSYL-GI +SKIQLYLNEHGFSESKLGSSETLP----------STSVYDILQFFYKLYYGELADKEFSE +EMTTILRRQVL-NGKIPKYLPDNTEIAHKTGELGM-YSHDAGIVYSKNG-PYIIVVLSDA +NN--KKTADETIAQISKEVYNYf +>[subseq from] Uncharacterized protein n=1 Tax=Kocuria rosea TaxID=1275 RepID=A0A378GZ73_KOCRO +---LAADLEELAAEVPGELGVVLLGPEGGEVV-ARNADRPFTSASLYKLFLAHAVLDRAD +RGALALSDVV-----------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW +EQVEAFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGSSTA +LLMGFLEEQHF-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG +WS-DYEESAPWFGDAGR------ +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces hoynatensis TaxID=1141874 RepID=A0A3A9ZG80_9ACTN +---------------------------RGGEV-ALRADEQVVIASIFKILLVLEFARQAA +TGRLDPRERIRVRAGDRLGGWGVAGCADDAELSLRDLAYFAMSVSDNTAADVLLRRI-GL +DVLPLLTAELGLTRTRVRGGPRQLLEVFDPEHTTSSTAREITRLLELIWQDAAGPPAACA +AVRELMARQVF-WTRLGSGFPPEVRLAAKTGTLP-GLHMEAGVVEYPDGGRYAIAVFAAA +ESSRGIDIDLAIGEAARTAVEH- +>[subseq from] Beta-lactamase n=2 Tax=Clostridium intestinale TaxID=36845 RepID=U2N4T2_9CLOT +------EIKRYLESRIGNYSFYFEDLHSGYMY-SYNENVQMVAAGCMKLPIAVSLIKSVE +EGRFTFLDKIKIESKDKVYGTGIIHEFNEREYTIFELLVAMLIQSDNTAANKIIDLV-SM +EKINKDIKEMGLRSTILNRKTTDERSD-QSELENITSAYDLSKIWKHLYNGTFLNKENST +MVIDILRRQQI-KNKLALYISDDYDISSKTGDKK-GVENDTELIQLSKGN-FVFTILSMD +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Beta-lactamase n=1 Tax=Parcubacteria group bacterium GW2011_GWA1_Parcubacteria_45_10 TaxID=1618789 RepID=A0A0G1NMC7_9BACT +-kEIESAFKEETKGLSGVYGLYVSRLDGSGSY-GVYEDDAFEAASLIKLPVLVALYKEAE +LGNVNLDEKYVLEESDKVGGAGSLQYKSAGTYSYRQLAQLMGNQSDNTAFRIVRNLL-GD +RKIQETANYLGMTKTSLSQN--------------ETSPRDVGILLEKLYGGQILSQESAS +EILNFLTNTLY-EDHLAAGIPSEIRVAHKYGREVH-VVNDAGVVFSD--KPFILVILSKG +VV--EPEADEVFPNLAKLIFE-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3L7YKX7_9CHLR +--------------YPFKTGWSFHDLVTGETA-NRFGDLVVPAASTRKVAILMTAMQSVN +RGELSLEEPVTIDERWQISDSGVFQFRPGFTITMHDVLLMMIIVSDNACTGIVCDRL-GL +DAINRFSQSVGMTGTVHREGIPQYTLSDARGTVNETTPNDVARLLHVILRASGVTPALAE +LALEMLSRQRL-RARLPFLLPGDTRVAHKTGTSGT-TYNDVGIVYRGDMPRFILAVYTSD +VPAIL------------------ +>[subseq from] Beta-lactamase class A n=1 Tax=Actinopolymorpha cephalotaxi TaxID=504797 RepID=A0A1I2QCC0_9ACTN +---------------PGRASVWFGRPGHPPAY-VREPDATHYAASTMKVAVLAAAYRLAD +EGLLDLDEQVPVHDDFESAGSSYHWALLGQSASLRWLARRMIVRSSNLATNLVLERV-GL +PAVAAAWSVAGARHSVVARGIQDYGA-EQAGLSNLVTAADLAGLLTALYDGTLASPQACA +QMLTVLLGQEV-TEDVVAGLPAGTPVAHKNGWVD-GVRHSAALVLPGDAPPYVLVTCVSA +DL-DEEAGCAVVARVAAATW--- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536MVP4_9CHLR +-dQLRSDLEAIARASGGRVGISLQELSGPRSL-SINGGQSFGAASTYKLVLLMAEAQQIA +SGQGRDSDLLCYAASDAEDG-WFMDYQPGSCYTRGELARRTGRYSDNTAAHILVRYLGGP +DALNRYAKSIGMNRSAL--WVP-----------NTTTPDDLSQAFVSEALGQLGGAAAQG +WLYPILTHTAT-EQGVPAGLPAGSTVVHKTGTMT-GTENDAAYVRNG-RIAYVLSVTVDG +LD--EGTAWSLVARVSARIWQY- +>[subseq from] serine hydrolase n=1 Tax=Kocuria rosea TaxID=1275 RepID=UPI000F6C6F06 +---LAADLEELAAEVPGELGVVLLDPEGGEVV-ARNADRPFTSASLYKLFLAHAVLDRAD +RGALALSDVV-----------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW +EQVETFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSAA +LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG +WS-DYEESAPWFGDAGR------ +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora pallida TaxID=145854 RepID=A0A1C6RPI9_9ACTN +-------LDARLAGVPGTVSAYVGRLDAAPTW-THAEHAPHYAASTMKVAVLAALYRAAD +AGTLDPDTPVPVHNDFPSADGPRFWQRLDRTAPLGWLAERMIVRSSNLATNILLGHV-GL +PAVAEVWALVGARHSVTGRGIDDAVAR-EAGITNLVTAADLAALLGALALGSLATPTSCA +TMLDVLCAQQI-RDDLPAGLPTGVRIAHKNGWVT-GVRHGVGVVLPDDAPPYVLAVCTTT +DLDSDDDACRLLADISAQVWA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sagamiensis TaxID=47875 RepID=A0A562WD94_9ACTN +--------DARLAAVPGTVSAHVGRPGADPTW-THAAHTPHYAASTMKVAVLAALYRAAD +AGTLDPDTAVPVHNDFPSADGPRFWQRLDRTATLRWLAERMIVRSSNLATNILLGHV-GF +PAVADVWTLAGARHSVTGRGIEDSAA-RAAGITNLVTAADLAALLGALAVGAVATPTSCA +TMLDVLCAQEF-REDLPAGLPAGVPIAHKNGWVT-GVRHGVGVVLPHDAPPYVLAVCTTT +DLTD-ADACRLLADVSAQVWA-- +>[subseq from] Uncharacterized protein n=1 Tax=Marvinbryantia formatexigens DSM 14469 TaxID=478749 RepID=C6L8W7_9FIRM +------------------------------------------------------------ +--------------------------------TILSSLDAMITVSDNESSNVLVRQLCGL +AKVNDFIARYGFSSTQQVNGIADPSLWVSDGRVNMTSPADCGRLLEMIYNGELVSHFYSF +RFETLLNRQQV-NYKIPDGLPEGVHISHKTGEVDD-TENDAAIIYTPYGD-YIFCIMSTD +LT-DTDAAVEHIHEVTRLIYNYf +>[subseq from] serine hydrolase n=1 Tax=Ruminiclostridium cellobioparum TaxID=29355 RepID=UPI00048072F0 +--ELKKIITDYTSKLPGRYGVTYIDLATGEMV-NVNDQVEYIAASTSKLPINMVLFKDIE +AGKVSLEDKLVYKEEDLEYGTGIIQNSPYGTYTVRETSKLAIRKSDNCGVNMIIRQV-GI +ENVRKYLTDLGGKVYY--------------GKTHRSCPYDMALVARDMYSHYLDNEAVYG +ELIDNLENTDW-NDRISAKLT-GVKVAHKIGNQTK-TANDVGIVFG--KHPYVLSVMTED +VD--FGTACNNIAALSKKI---- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora krabiensis TaxID=307121 RepID=A0A1C3NDH2_9ACTN +-------LDARLAEVPGTVSAYVARPGAAPTW-TRRADDTHYAASTMKAAVLAALHRAAD +TGTLDLDTPVPVVNDFASADAPRFWARLGDRAPLRWLAHRMIVRSSNLATNLVLAHV-GL +PAVADVWALAGARHSVTGRGIEDFAA-RDAGITNLVTAADLGALLGALATGALAPPAACA +AMLDVLAAQEH-REDLAAGLPPGTRIAHKNGWVR-GIRHGAGVVFPDDAPPYVIVVCTTT +DPDNDEDACQLIADVSAQVWT-- +>[subseq from] Beta-lactamase enzyme family protein n=1 Tax=Meiothermus granaticius NBRC 107808 TaxID=1227551 RepID=A0A399FBQ7_9DEIN +--SLSDELQAHIQAFPGQVGVWLEHLSSGETF-AHQPQRPFLAASTIKLPMLCYALATRA +----DLSQNIPIKPEVVALGSGVLKDLSPGLLPLRDLLTLMIVLSDNTATNVVLDHWGHK +EPFNAYYRAQGWSQTHVAGML-SLPERLPGD-AAKTSAQDLGRLLKALWRGELLPPDATK +TALDILSRQQF-TAFLRYLLADLIRLYSKSGEIRC-CRHDTGILARGEQA-LSITVLTET +ETHPDHPATLLIGRIAEVAYRYw +>[subseq from] Beta-lactamase n=1 Tax=Agromyces sp. Root81 TaxID=1736601 RepID=A0A0Q8VYG6_9MICO +----LRDAAEVLSSAGLRASIVVRDLGSGRQL-SIAADDAYPLASVVKLPLALAVLQLID +EGRLDPARPVTLEPADRTPQTGYSRFRHPTTVSIEDLLYMAVCLSDDTAADALFELC-PP +AEVTASLRETGIAGITVRHSIRELHRQLDVSSANAGTANACVELLDRIWRSPAFDG-QKD +RLRGLLAMNVM-RQRLAPDLEDDAAWHSKTGTFLH-LRHEIGVLEHADGRALAIAVLSES +SVQRQPAAEQALGLAAKLL---- +>[subseq from] Serine hydrolase n=1 Tax=Veillonella sp. T34266-5 TaxID=2027457 RepID=A0A2S7Z8V4_9FIRM +--SLEIQLAALLDTLDATVSYMVTRLNEGEEA-TIVASSKHTGASMVKTLILEYVFHLAA +QEQLDLNDTIALSRSPRVEGAGALMELVGNHFSYLELCRLMMVLSDNWATNLLMQAL-GM +ENINARAEQLGLEHFEINRMMMDFTAA-KENRENYITAMDMAVLLHHIYEL--RHTIYGH +EMWNILGRQQF-RDILPFHWGEDVVFHHKTGSLDR-VEHDAGIIETMNGD-FCFVLLMSH +LDND--KAKQLGA---------- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_20CM_2_70_9 TaxID=1805058 RepID=A0A1Q8A6P7_9CHLR +--DLASALDQAAAGVPGMVSVVVVDVDSGYVY-ERRADERVEAASLFKLFVMAALYRRAL +DDPQLLEVIVPVSRPRLTAGQV---DYVLEPVAVREALEEMIDWSDNEATAALVELL-GT +DEVNATIASLGLRDSVVRSGEATGN---------STSARDIGRFLTLLARREVVAPEASD +AMTWLLLRQGI-NDRLSLGMPKDALFAHKTGNSA-GTFHDAGIAWTAWGE-RVLVVLTDG +VAPP--DARALMKDLG------- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Actinoalloteichus hoggarensis TaxID=1470176 RepID=A0A221VY31_9PSEU +---LNEHLQSELAVGGLRGGFLARDLTSGLQI-GFNENAVFASASLAKIPLAVAILDRID +AGVLDRAATVTIAPTPTGYGPPGLSSRHPATLAVEDLVYLSVALSDNTATDALFDLV-PP +ADVTAHMREIGILGIQVRHRTRDLQQQLDTSHANTGTAAGFTDLLQALWTPSLIPLRSSQ +HVRALMAGNVHRHRLTPDFVSDSSTWSSKTGTLLN-LRHEIGVIEHADGQTIAITALTQS +RIAQQPAADILIARTARALHDH- +>[subseq from] Putative endopeptidase p60 n=1 Tax=Moorella humiferrea TaxID=676965 RepID=A0A2T0AM18_9THEO +-sSLKKQIEDFLATQAGTYGVYFKDLISGQSF-GINADMPLPAASTVKLPTVLFINHLVA +QGNLDWQQKLTYNSTDYQGGSGILQFSVKDGLTLRTLTTLAITTSDNIAYNMLRNFV-GK +ESVAAFMRSLGGQTVFP------------N-GQNLSTARDMATYVQAALDFAKVNPDGRR +LLDD-MANGIY-NEGIPLKIPDGVTVAHKEGFIW-GSPDDVGVVFG--SRPFIVTVLSQG +VD-DPDQGFANIATITRMMYDY- +>[subseq from] Beta-lactamase n=1 Tax=Bacillus nealsonii AAU1 TaxID=1202533 RepID=R9C9N7_9BACI +---LSKRINEIVQEYKAHGHFGITIEWKEKCF-YFNAKDVFPSASLIKLPILLEGFMQSS +SGTLVLDDLERVKDIQKVGGAGIVQYMSPQSLSVHDLLTLMIIVSDNMAANYLIERL-GM +DRVNRRCQQLRMSSTILQRKMMDQE-ARERKLENYTSPLDIIRCLKAIQNN------KNQ +SCKKILSHQQL-LDKLPYYFEENIRIANKTGELDK-VEHDCAIIEHEDE-IIYVAVLTDQ +LTTN-FKGKQIIQLIGASIL--- +>[subseq from] serine hydrolase n=1 Tax=Prauserella coralliicola TaxID=1401264 RepID=UPI000D93CD7E +----AESIAEHWREVGATGHLLARNLDTGEHL-GFDVDTPVPLASVAKVPLALVVLDRIA +EGDLDPALAITIDPATKSLPSGVAAFRYPATLAVGDLLHLTLTVSDNASADALFDLV-GV +EHVDRRLRDWGCTGIRIRHRMHRMYETLDPAHANVGSATALVELLQRCWLDEVSRPDATA +ELRRLMALQVF-NQRLSSDLRADMRVSGKTGTFLH-LRHEIGVVTAESGDRVAIAALTRS +ARRAAHDIDLAIGAAARSAF--- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces jeddahensis TaxID=1716141 RepID=A0A177HI62_9ACTN +------------------------------EV-AVDADDLVVIASIFKVLLVLEFARQVV +AGQLDPRERMRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLSRV-GL +DTVRLLGEELGLVRTRIVGGPRELLEVLDPRHTTASTPREITRLLQLIWSDAAGPPEACA +LVRDFMSRQVF-RHRLVSGFPDDVIVAAKTGTLP-GLHMEAGVARYPDGQCYAIAVFART +QDASRATVDAAIGKAAGI----- +>[subseq from] Serine hydrolase n=2 Tax=Chloroflexi TaxID=200795 RepID=A0A5N9BW42_9CHLR +--DLRSKVLGIIDDFSGTASVSANNLTTGEVL-SINEKKVLPALSAIKIGIMAELFFQIH +EGEYNLLDRVKIDASDLRGGTGVFREMETPFVTLKDICMMMIVVSDNTCTWKLSSML-GI +DSINKRMRSLGLNEYSLNHDLPTAFDDMQGKDVNECSARDFTNLVTLMAKGELVSKESSD +AMLDIMGRCQH-IEWLGRYLPPKVKMYNKLGAYLH-ARCDTGLIKSENSD-YVITVFASY +SKDKPHEGSRLIGEISKAVYDFw +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Woesebacteria bacterium RIFCSPHIGHO2_01_FULL_37_10 TaxID=1802489 RepID=A0A1F7XY25_9BACT +-----------TENLSGVYTLYLVRLGNGSNY-GVNEKDAFQAASLIKLPVMAAMFTEVE +EGRLSLSSKYKLKSSDKVKGSGSLYNKPPGYITYENLIKLMGKESDNTAFNIGRKYL-GD +EKIAEVIGKIGMKNTSLE--------------ENSTTSEDIGVFFQELWNGNTLNNDHKE +MLLEYLTDTIY-ENWLPSGIPEDIRVAHKFGRELH-VVNDAGIVYAND--PFVMVMLSEG +IV--EKEADLVIPEIASGIYE-- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Clostridiales (miscellaneous) TaxID=39779 RepID=U2D0X1_9FIRM +-dDIQQKVKQYLGNNISKVGIGYYDIETGKGF-SINGDKYFTAASTVKVQMNMILFDMIR +EGKINIDETVKYSQDDYEGGTGVLQGEDKSKIPIQKLSDYSIMYSDNIATNMIIRKI-GY +SEMKRFADKLG--------------HSIPQD-ENVVTPNEELAFLKMLYNNKG-NNTYYA +RLISIMKTTVF-HDRLDKYVPQN-IVAHKVGDYGE-FINDVGIVYSS--KPYIIAVYTKN +LS----NANEIIANINKIIYNY- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora avicenniae TaxID=1198245 RepID=A0A1N7EMN9_9ACTN +---VAESIAEQWQQVGAGGHLLARNIDTGEEL-GFDIDVAVPLASVAKVPLALVVLDRIA +AGELDPAMPVTIDPATKSLPTGVAAFRYPATLAVADLIHQMLTVSDNASADALLDLV-GV +GAVDERLRAWGCGGIRVRHRMQRMYETLNPAYANVGSAAALVELLQRVWLDRISRPEATA +ELRRLMALQVF-NQRLSSDLRADVRVSGKTGSFLH-LRHEIGVVTTESGERVAIAALTRS +HRRAAHDIDLAIGAAARSAF--- +>[subseq from] serine hydrolase n=1 Tax=Nocardiopsis sp. FIRDI 009 TaxID=714197 RepID=UPI000E2620D5 +---------------------HVREIDGTAEV-AHRADEPVVLASVAKILIVLEFARQAA +TGRIDPAERVVARRADRLGGTGIADFADDVELSLRDCASLAMTVSDNTAADLIVDRI-GV +EPVRLLTEELGLDHTRFTGGPRSLLHTYDPARATSGSMRDLTLLLSLIWTDRAAPPDACA +FVRALMARQLV-RARIASGFPPPTRVSAKSGTLP-GLRQEAGVVEYPDGRRYAVAVSATV +TDPDHPETDLALGRAARSAV--- +>[subseq from] uncharacterized protein LOC111363712 n=1 Tax=Spodoptera litura TaxID=69820 RepID=UPI000C1429B2 +------------------------------------------------------------ +------------------------------------------------------------ +--VNDYIHKIGIKEIAIVASEEDMHKAWDVQFGNWTKPMAAVELLKIFYDKKVTSKANFD +FLWKVMLDSPTGKKRIKSQLPEGTLVAHKTGTSGTNAVNDIGIVTLPNGKHFAISVFVSN +SKENEETNEKIIADISKLAWDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Catellatospora citrea TaxID=53366 RepID=A0A419XCJ5_9ACTN +-----AEAREALRDAGLRGSFLVRDLDSGQEM-GIDADVVWPVASLVKVPIAVATLERAA +RGELDPAAPVTVQPGRVSTPTGLTRFRHPATLAVEDLAYLAVAVSDSTAADALLALT-GP +AQVTAELRRLGVAGISVRYLMRELASQLDIARANTGSARAFVDLLHALWRPSTMHTAVAE +RVRELMGATVM-RHRLAPDFSSDASVSSKTGTLLN-LRHEIGVVEHADGQTFAVAALTES +SVAVQPEAEALMAHVARTLRD-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. sk2.1 TaxID=2478959 RepID=UPI0011E86013 +-----------SAALPLTLAVAAVDIDGGGTV-GVDEHTVLPVASASKLLLLAEVAHRLD +GGELAADRVVEVLDEDVAEGTGLLRRLSGRDWTVEDLAWLTASVSDNTATNALLRLV-GR +ESTARRARELGLDHLTLHDKVRDVRGPDVPPVFATGTARDLARLVAHAVRGTMSGPAASA +RLLRWMRANTD-HGLVPALIDDGLLVANKTGTDT-GVRADAGVIVGRRRLAYAVVAHWDT +ALSTERAAVHAIRDVGRTL---- +>[subseq from] Serine hydrolase n=1 Tax=Kibdelosporangium phytohabitans TaxID=860235 RepID=A0A0N9I1B4_9PSEU +---TVETINARAEEVGVRVRLHAAEIDGTRQI-GIEGGVPVVTASVFKVPIALELARQAA +DGGLDLGELVTVAPGHPTPPCGLATFRHEVTMSWHDLAILMIGISDNVATDLILARV-GN +QAVGHSLRRMGFEHTTVTQDCGEILDALRPEHTCATTAEEITRLLGLIWRDEAASPAACA +DVRRWLELQVW-PHRLRSGFPDDIRVSGKTGTLPS-VRNEVGVVEYSDGGRYAVGVFTDA +VDSRVPERDAFIGFAAARA---- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A350T083_9CHLR +--DIERDARALIDAFDGDAAFFAQNLLTGEEV-GFRADSVMPTASTIKLLVLAEVIRQAE +AGQFALDDPLPMISEDQSGGSGILKDLSPATLTIRDHATLMIALSDNTSTMALVRLA-GR +ARIEQAGQEWGMTATTLP-----IDRAPDGDARDYSTPRDIVHLLQLIATDALVSPAASA +TVRDILVTQQY-HDQIGRYLPYNIVVRSKSGFMTDSVRVDAGIIEISGVQRYVLCLMTEH +HP--------------------- +>[subseq from] Serine hydrolase n=2 Tax=Kribbella sindirgiensis TaxID=1124744 RepID=A0A4R0HZJ5_9ACTN +----NARIRGIFEDAGVRGWMHAISLDDPEARvELDADVVVPLASVYKLPLLAGFSRLVD +LGELDPREQVTLEPSSRTAGPTGLSMFADPVVSLRDLALSMATVSDNAAADALLDIV-GL +RRLAGILESFGLRRTWVRRGTAANLRVYEAASGSAASARDLTLLLRRLWAGELLSAEQTE +FVKATMHRQIF-LQRVASGFPDGVRIAGKTGTFG-ALRHEAAVVTLPDGAAFAIAILTLA +ARGDQPRVEAAIGEAARVAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Thermoclostridium caenicola TaxID=659425 RepID=A0A1M6C769_9FIRM +--ELRAMVEDFIGKQSGRYGVTFIDLATGESF-GINDKEEYIAASTSKLPMNLLLYIKIE +SGEVDPDMMLEYKPSHLEYGTGIIQNSPYGTYSVRETSELSLRKSDNCGINMIIELL-GI +ENIRQYIVDLGGV--------------VYYDKRHRSCPYDMALVAQELYRRYLSNPAVYE +KMIEDLENTDW-SDRIDALLPDHVRVAHKIGNQTR-TANDVGIVFAS--HPYVLSVMTEE +VD--FGTACKKIAEMSKMIYE-- +>[subseq from] Putative beta-lactamase (Class A) n=1 Tax=Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a) TaxID=367928 RepID=A1A306_BIFAA +------------------------------------------------------------ +-----------------------------EDASLDGLLEQMITVSSNEATNALVERLGGF +GVVNSVAAQYGFNESHLNSRMGDLSNY----STKQTSVADQGRFLAAAYRGQLVSAGYSK +RMTDIMSRQTR-RAKIPAGLPQGVACANKTGEAP-GVENDSAIVYG--EHPYVIAVMSSD +VP-DSSAAQAQIRDISSTVWA-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. B006 TaxID=2201999 RepID=A0A385AUQ9_9ACTN +------ELDAHLDKVPGTVSAYVGRPGAGPTW-TRRADATHYAASTMKLAVLVALFRAAE +AGRLDLDAPVPVRNSSALPGAPRFWDRVGGDAPLRWLAERMIVRSSNLATNICIGQV-GL +PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALAPPSACT +AMLDVLAAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT +DLADEDDACRLIAHVSERVW--- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus cereus VD142 TaxID=718224 RepID=J7T5F2_BACCE +----------------------------------------FMHPSTVKGLVTRVLLLQYP +--IKKLDEVITYTKDDLVEYSPSAEKHVDTGMTLREIAEATIRYSDNTAGNIL----DGP +KGFEKALKQIGNKVTMAACLEPALNEAIPRDIHDTSTAKTFATDLKAFTVRDALQTDKCK +IPTDWMRGNAT-E----------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ADI95-17 TaxID=1522759 RepID=A0A3N6EJH8_9ACTN +-----------SAALPLTLAVAAVDIDGGGTV-GVDEHTVLPVASASKLLLLAEVARRLN +TGELPADRLVEVLDEDLAGGTGLLRRLSGRGWTVEDLAWLTASVSDNTATNALLRLV-GR +ESTARLAQELGLDHLTLHDKVRDVRGADVPPVFATGTARDLARLVTHTVRGTMSCPAASA +RLLRWMRANTD-HGLVPALVDHDLLVANKTGTDT-GVRADAGVIIGRRRLAYAVVAHWDT +ALSTERAAVHAIRDVGRTL---- +>[subseq from] serine hydrolase n=1 Tax=Clostridium tertium TaxID=1559 RepID=UPI0012C70E5C +-----KEIKKYLESRIGTYGFFFEDLKSGYIY-GYNENVQITAAGCMKLPIAVSLIKAVE +DKKLDFLDKIKIDGKDKVYGTGIIHEFNEREYTLFELLVAMLIQSDNTAANKIIDIL-TM +DKINENIDEMGLKNTILNRKTTDER-NSKDEIENITSALDLSKVWKHLYNATYLNKENSQ +MLIDILMRQQI-KNKLALYIPDDYEISSKTGDKA-GVENDTQLIRLSKGN-FSFTVLSMG +IPNS-VYGTVTLAKCGKMMWD-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536PR82_9CHLR +-dQLRSDLEAIARASGGRVGISLEELSGPRNL-SINGGQSFGAASTYKLVLLMAEAQQIA +SGQGRDSDLLCYAASDAEDG-WFMDYQPGSCYTRGELARRTGRYSDNTAAHILVRYLGGP +DALNRYAKSIGMNRSAL--WVP-----------NTTTPDDLSQAFVSEALGQLGGAAAQG +WLYPILTHTAT-EQGVPAGLPAGSTVVHKTGTMT-GTENDAAYVRNG-RIAYVLSVTVDG +LD--EGTAWSLVARVSARIWQY- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536H9S2_9CHLR +-dQLRSDLEAIARASGGRVGISLEELSGPRNL-SINGGQSFGAASTYKLVLLMAEAQQIA +SGQGRDSDLLCYAASDAEDG-WFMDYQPGSCYTRGELARRTGRYSDNTAAHILVRYLGGP +DALNRYAKSIGMNRSAL--WVP-----------NTTTPDDLSQAFVSEALGQLGGAAAQG +WLYPILTHTAT-EQGVPAGLPAGSTVVHKTGTMT-GTENDAAYVRNG-RIAYVLSVTVDG +LD--EGTAWSLVARVSARIWQY- +>[subseq from] Uncharacterized protein n=1 Tax=Blautia hydrogenotrophica (strain DSM 10507 / JCM 14656 / S5a33) TaxID=476272 RepID=C0CNH6_BLAHS +------------------------------------------------------------ +---------------------------------LNHLLELMITVSDNEAYNELMRRLGGC +QRVNQYLEREGYENTEVHHTLHPSSSASLGDGSNLTSVKDCGKLLERIYYGDCVSETASV +KMLKWLCRQQT-DWKIPAGIPKGIQIANKTGETDT-CQHDIAIVYAPSTT-YLLCVMSCE +LL-SENEGISRIQQLSAQVYEYf +>[subseq from] Serine hydrolase n=1 Tax=Mumia sp. Z527 TaxID=2585212 RepID=A0A5C4MGF7_9ACTN +--------------------AYRLATAAGDVLaERAATTPFYAASTIKVAPLVAALRLVE +AGTLTLDDTLVTRDTSQVPEAPDYG-MPPAGMRLADVLERMIVVSSNEATNMVVERV-GL +EAIAQVLSDAGAHDSRMTRQFGDQAAAEAYGMSNVVTAADLASLMGALVSGRLAGPHATT +WMTDVLSRQQT--PHIAANAPEHLPWGSKSGSVD-AIRHDVAYLGPPGAGTVVMAVCTRG +YP--AEDADETIAALGDLA---- +>[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Kryptobacter tengchongensis TaxID=1643429 RepID=A0A656DDR1_9BACT +---------------------------------------------MIKVPILVELFYKFE +EGKLKKDTLVSLEDSLKYGGSGVLQYFYDGAIKLIDAAVLMIILSDNTATNLVLDCFANL +DAVNNRMKELGLDNTKILNKLMSFKTKKKTPEAGYTTPNDMVKLLELLANGKIINPNVSA +EIINIMKNNQD-YEMMKRYLPENIVVANKSGSIDR-MKADIGIVYAKCT-TYAVAIFCDE +LSTVDNKGHLAVAEISKLIFDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora matsumotoense TaxID=121616 RepID=A0A1C4U2P8_9ACTN +-------LDARLDRVPGTVSAYVGRLDAPASW-TRTPDATHYAASTMKVAVLVALYRAAE +AGTLALDAPVPVVNEDSARDAPRFWERLGGQATPRWLADRMITRSSNFATNLLIDRV-GL +PAVAEAWRLAGARHSVTGRGIEDAAA-REAGITNLVTPADLAALLGGLAAGPLASPAACA +AMLDVLLAQRH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVLPDDAPAYVIAVCTTT +DLDDLDDACRLVAEISATAW--- +>[subseq from] serine hydrolase n=1 Tax=Kitasatospora mediocidica TaxID=58352 RepID=UPI000559D0F7 +----TDDIREIFERAGCEGALCVQPLEGDAEV-GLLADEPVVPASVVKVQVALEAETWFV +EGRLDPCERVTLSAADRTPGPVGISLFNDDALSWRDMVVLMLTISDNDTTDALLRRV-GV +GALNATATRLGLTGTVIESDLRTMLDALDPSQGTRTTPRDMVDLLRLIWTDQAGPAAACE +RVRAAMARQVT-RHRIASGFRLPVRVAAKSGSLAGVIRNEIGVISYPDGRRYAAAVFTRS +RPSDDAAISRAIGAVTAQA---- +>[subseq from] serine hydrolase n=1 Tax=Kocuria indica TaxID=1049583 RepID=UPI00138ED5F4 +--ELHDDVATMLHAADMTGAVSVRVIGSDRSF-NYRAGVRFPMASLYKLVVMAAFCQAVD +DGLIDPAAPVELVPETRVPGPTGLSICLDPVMSWRDLVRLMMTISDNTAGNAVLCAV-GL +DRVAHTLRRLGLLQTDIRPYLPATDLEYDPLLVSSTTTSDLVDLLSFIWEDHAATPSQCS +FMRHVLGQQAWGHRFAEVFTYPGVQIAAKTGSLA-ALSHEAGVISHPDEPPIAVAVLTQS +ARRTIPLSNTVVGQIARHCVRSy +>[subseq from] Beta-lactamase class A n=1 Tax=Anaerobacterium chartisolvens TaxID=1297424 RepID=A0A369B956_9FIRM +--EFKSELEDYVSTFKGQYGIYFWDLNTDISF-GINESDEYLAASTVKIPINLYLFNKIK +DGEIDPEEKLVYTKSTDYEGTGIQYQNDGTEYTIRELSALSIRESDNVAVNMLIRKL-DR +QNYKDYMKQSGGVVV---------------TEKNESCPSDMALYMKAIYDFYNENPDVGG +ELIDSLQSTIY-NDRIPKLLPKAVKVAHKVGNQL-GALHDIGLVFAD--RPYVIAIMSKN +IN--EEEGYDVIANISKKVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Kocuria sp. WN036 TaxID=2032628 RepID=A0A2A2G5P1_9MICC +---LAADLEELAAGVPGELGVVLLDPEGGEVV-ARNADRPFTSASLYKLFLAHAVLDRAD +RGALALSDVV-----------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW +EQVEAFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSTV +LLMGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG +WS-DYEESAPWFGDAGR------ +>[subseq from] serine hydrolase n=1 Tax=Nocardiopsis quinghaiensis TaxID=464995 RepID=UPI0012394F2B +-----------------VVRVHAREIDGTGQV-GRLADEPVVLASVAKVLIVLEFARQAS +TGLVDPTERVVVRRDDRLGGWGTADFADDVELSLRDCALLAMTISDNTAADLIVDRV-GV +EPVHLLATELGLERTRFTGGPRALLHARDPSRTTSSTPADITRLLRLVWTDAAAPPRACA +FVRDLMARQLV-RTRIASGFGPDVRVSVKSGTLP-GLRMEAGVIEYPDGGRYAVAVCAAG +PDRTALEADMALGRAAREAV--- +>[subseq from] Beta-lactamase n=1 Tax=Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) TaxID=369723 RepID=A4X9J3_SALTO +-----------LDRVPGTVSAYLARLDTAPTW-IRHPATTHYAASTMKVAVLVALYRALE +AGRLASDTAVPVRNEFDSAQPGAAWDRLGGTAPLRWLAERMIVRSSNLATNLLLDQV-GL +PAVADVWARAGARHSVTGRGIEDFAA-RAGGITNLITAADLAALLRDLALGALATPESCT +AMLELLVAQEH-REDLAVGLPVGARIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCTTN +DDPDHSPDEDACQLIADISAR-- +>[subseq from] Beta-lactamase n=1 Tax=Bifidobacterium adolescentis TaxID=1680 RepID=A0A1X2Z9V0_BIFAD +------------------------------------------------------------ +-----------------------------EDASLDGLLEQMITVSSNEATNALVERLGGF +GVVNSVAAQYGFNESHLNSRMGDLSNY----STKQTSVADQGRFLAAAYRGQLVSAGYSK +RMTDIMSRQTR-RAKIPAGLPQGVACANKTGEAP-GVENDSAIVYG--EHPYVIAVMSSD +VP-DSSAAQAQIRDISSTVWA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora zamorensis TaxID=709883 RepID=A0A1C5IKP7_9ACTN +------DLDAHLDRVPGTVSAYVGRPDAPPTW-TRHPDAAHYAASTMKVAVLAALHRAAD +AGTLDLDAPVPVVNEDSAQGAPRFWDRLGGTASLRWLADRMIVRSSNLATNLVIGHV-GL +PAVAEVWARTGARTSVTGRGIEDFAAR-EAGITNTVTAADLAALLGALATGRLASPAGCT +AMLDVLIAQEH-REDLAAGLPEGTRIAHKSGWVR-GVRHGAGLVLPDDAPPYLITVCTTT +DLEVEDDACRLLAHISAQVW--- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V7AFJ4_9BACT +--DLVKRLNALCDGMPFQTSWYLKDLGSGAQA-DRLGAVPVPSASTRKTSILMSALAAVH +AGKLALDQKVTIEARYQDNDSGTFQFLTPGFITLRDALVMMIIVSDNTCTGLVVDLV-GL +DNVQRYCDAVGMKSTIHRYGMPKLSVGHSLEQVTTTTPQDQGLLLELILKGTQCTRELCR +LGLDILSWQRL-KTRLPSQLPLGTRVAHKTGTGPR-GYNDAGIVFKGDRALYILTAFTEN +VPAAFAAAYQVIGRMARMAWD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Clostridium sp. DSM 8431 TaxID=1761781 RepID=A0A1I7G8W4_9CLOT +-----KEIKRYLESRMGKYGFYFENLTSGFVY-GFNEHKQMTAAGCMKMYIAVSLIKAVE +DKKVDFMDKILVNRDDKVYGTGIIHEFNEREYTVFELLVAMLIQSDNTAANKIIDLI-GM +EKINSDIKEMNLKNTFLNRKTSDERNS-SYGIENITSAYDLGLLWKKLYRGEFLERDNGI +MLIDILTRQQK-KNKLALYIPDDVEISSKSGDKK-GVENDTELINLDKGE-FTATILSEG +IPN-SVYGIMTLAKCGKMIWD-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535YJM7_9CHLR +-------------DPDGDYAVVMEDLKSGARV-AVNESQVFPSASLYKLGVAWMVLRQVD +TGMLHLDGPLDIAEPDTIEPEPDGGVAAGDRPTVREALADMLTISSNAAAHAFLRTL-GR +VDFNREMQRIGLSQTRIPEDVDADG--SDGDAQAVTSAADIARLLRLMATSQQLSAAARD +VLSECLASGAP-PDALRETLPAGIDVLEKTGNLDD-ASNVGALLQSARGT-VILVVL-DH +AV-DPGDARAVIAQAGQVAYK-- +>[subseq from] Serine hydrolase n=2 Tax=Kribbella sp. YM55 TaxID=1572660 RepID=A0A4R0IIP0_9ACTN +----NARIRGIFEDAGVRGWMHAISLDEPEASvELDADVVVPLASVYKLPLLAGFSRLVD +LGELDPREQVTLEPASRTAGPTGLSMFADPVVSLRDLALSMATVSDNAAADALLDIV-GL +RRLAGILESFGLRRTWVRRGTAANLRVYEAANGSAASARDLTLLLRQLWAGELLSAEQTE +FVKATMHRQIF-LQRVASGFPDGVRIAGKTGTFG-ALRHEAAVVTLPDGAAFAIAILTLA +ARGDQPRVEAAIGEAARVAVD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. Ncost-T10-10d TaxID=1839774 RepID=A0A1C5CLG0_9ACTN +------------ATLPLTLAVAAVDIDGGETV-GVDDRTVLPVASASKLLLLAEVSRRLD +TGELLADRPVEVLDEDVADGTGLLRRMSRRGWTVEDLAWLTASVSDNTATNALLRLV-GR +ESTARVAKELGLDRLTLHDKVRDIRGPDVPPVFATGTARDLARLVTHAVRGTMSSPAASA +RLLEWMRANTD-HGLVPALVDDGLLVANKTGTDT-GVRADAGVIVGARRLAYAVVAHWDP +ALSTQRAAVHAIRDVGRTL---- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces yanglinensis TaxID=310779 RepID=A0A1H6DLY5_9ACTN +------TLAELFDRLGCEIALCVQALDGAAEF-TLAADRQVTPGSTMKVQVALEAETWFA +EGRLDPREQVALPAEGRTPGPVGLSLFADEALSLRDMVTLMLTISDNPSTDALLRRV-GT +GAVNATAARLGLTGTVVTSDLATLVDTLSPTTGTRTTPYDMARLLRLIWTDQAGPPEACA +RVRAVMARQLT-RHRLAAGFRRPVAVAAKSGSLLGVVRNEIGVITHPDGRRYAAAVFTRS +RPADDAAVNAAIGTAAARAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3C0XPI1_9CHLR +---------------------------------THDDNVAFISASLYKLGILAHVESLVD +AGTLRYTDTIEIQPEDITDGS---YELAGTVMTVDEALEAMITVSDNGTALAFWRSL-GP +DNINATMQTLGLGDFHIANDD---------SDDNTATARVIGRYFTLLAQRKLVSAAASD +RMLARLERQQV-NDRLPSELPDGTVVAHKTGNLGF-ATHDAGIIYTPSGP-RVVVGMTAN +GDE--EEA--------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Nocardioides terrae TaxID=574651 RepID=A0A1I1LH78_9ACTN +------------------VSVWLADLDGTVRQ-AQNVNHQHYAASLVKLPIALAAYRMHD +RGELDLDAVVPVHPDFASAVEGERETWAADTVPLRELVARSLARSGNLAANLVLEQV-GP +AEVAAVLADAGCSMTEVGRAIEDAPA-EEAGLTNLMTAHDAGRLLAGIAERTLASAAACQ +EVEQVLTRQRH-RDGIPLGLPEGTAVANKTGWVD-GVRHDIALVRPDDRPGFVLAILTSG +LDD--DEAEWRISELARFLWQ-- +>[subseq from] Uncharacterized protein n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A3B8K7B9_9FIRM +-------LEREIQKSRFKISLCLYDFQTKQWV-EKNAGQTLYPASLIKLLYLLTALEQLE +RGILSLTDKHILTDADKYVGSGSLQAEIGSSYTVAELLRLMISASDNIAANIVLDLV-RP +EAVSAMAARLGLTKTRGTRKMYALESSLP---PNLSTARELTELLVALENKQVCGEGLKN +LAVSMMLETEN-KQRIGRYIHKDALVANKVGTVDH-MVGDMALLYFPHRPPLALTIMISL +SPCRLAVVNAMARRAAGAA---- +>[subseq from] Serine hydrolase n=4 Tax=Bacteria TaxID=2 RepID=A0A2I1NZU8_KOCRH +--QLGREVAEILQSEDMTGAVSAIDAPELPVF-SFHEEEVFPAASLYKLAVMMAFCREVD +HGVLEPSALVDLSPADRAQGPTGLAILEDMVISWRDLVRLMMSISDNAAAEAVLRKV-GT +SRVHETLRLMGATRTEIRPTPPSGNGEYDPLSVSSTTASDLVTLLCAIWQDRAASAEQCA +FMRQVLSQQAWGHRFAEAFSYPGVTVAAKTGSFGS-LSHEAGVVSHPGEKSIAVAVLTRS +VRRQIPLSNKVVGQIARHCVRNy +>[subseq from] Serine hydrolase n=1 Tax=Nocardiopsis sp. CNR-923 TaxID=1904965 RepID=A0A1Q9TM45_9ACTN +-----------------TLRVHAREIDGTAEE-AHRADEPVVLASIAKILIVLEFARQAA +TGRLDPAERVVARQEHRLGGIGTSDFADDVELSLRDCAALAMTVSDNTAADLIVDRV-GV +EPVQLLAAELGLTGTRFTGGPRSLLHDYDPARATSATPRDLTLLLSLIWTDRAAPPDACA +FVRALMARQLD-RSRIASGFPPAVHVSAKSGTLP-GLRQEAGVVEYPDGRRYAVAVSATV +TD--------------------- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. BL1 TaxID=2478709 RepID=UPI000EF57655 +------ELDAHLDRVPGIVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE +AGRLDLDAPVPVRNSFDSAGAPRFWDRVGGEASLRWLAERMIVRSSNLATNICIGQV-GL +PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALASPAGCA +AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT +DLADEDDACRLIAHVSERVW--- +>[subseq from] Beta-lactamase n=1 Tax=Agromyces cerinus subsp. cerinus TaxID=232089 RepID=A0A1N6E7S3_9MICO +----LRDAAEVLSSAGLRASIVVRDLGSGRQL-SIAADDPYPLASVVKLPLALAVLQGID +EGRLDPARPVTLEPAERTPGQGYSRFQHPTTVSIEDLLYMAVCLSDNTAADALFDLC-PP +AEVTASLRETGIAGITVRHSILELHRQLDVSSANAGTASACVDLLDRIWRSPSLGGQ-KN +RLRSLLAMNVM-RQRLAPDLEDDAAWHSKTGTFLH-LRHEVGVLEHADGRALAIAVLSES +SVQRQPAAEQALGLAAKLL---- +>[subseq from] serine hydrolase n=1 Tax=Ruminiclostridium papyrosolvens TaxID=29362 RepID=UPI000E3DEF25 +---LKKLITDYTAGLSGKYGVTFIDLATGEMV-NVNDTDRYIAASTSKLPINVLLYKNVE +AGKVNLDDMLTYQKEDVEPGTGIIQKSAGTQYTVRETSKLAITKSDNCGVNMLIRLL-DI +QNVRQYLVDLGGKVY--------------YDNHHRSCPYDMALVAQDLYKHYIKNEAVYG +ELINNLENTDW-HDRIDAQLT-GVKVAHKIGNQVK-TANDVGIVFAS--HPYVLSIMADN +VD--------------------- +>[subseq from] Uncharacterized protein n=2 Tax=Candidatus Woesebacteria TaxID=1752722 RepID=A0A1F8D086_9BACT +-kKISEEFKNITKNLSGVYGLYVIRLNGEGAY-GIFDKEKFEAASLVKLPVLATLYKEAE +AGNIDLDTKYSLKNSDKITGSGSLSGKPAGTLTYRDLARFMGKQSDNTAYGIIKRIL-GD +AKINKEISDLGMTNTSLSD--------------HSTSPYDTGIFFEKLYKNQIVKEKYKN +EILDYLTDTIY-ENWLVAGIPEEIRVAHKYGRELH-VVNDAGVVFTK--EPFILVIMTKG +VV--EREADEFFPELTKVIYD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora tulbaghiae TaxID=479978 RepID=A0A1C4VU92_9ACTN +------ELDAHLDKVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE +AGRLDLDAPVPVRNSFDSAGAPRFWDRVGGEAPLRWLAERMIIRSSNLATNICIGQV-GL +PAVAQAWALAGARHSVTGRGIEDFAAR-DSGVDNLVTAADLAALLGELALGALASPAGCA +AMLDVLVAQEH-REDLAAGLPDDTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT +DLADEDDACRLIAHVSERVW--- +>[subseq from] serine hydrolase n=1 Tax=Granulicella sp. S156 TaxID=1747224 RepID=UPI00131B8F44 +-hELLAQLQPILSAHHGKVALYAVQLNTGKTV-GIDQSLPVQTASDIKLAILYEAMVEVR +EGKAHWDEKLVLKPGDPVSGSGVLLFFDTPIVTLKDALTMMVIVSDNTATNMMIDRF-GV +DPVNARMVALGLTNTHLYKKVMKPATDQPKFGLGKTTPYEMAVLMTRIGRCELH------ +------------------------------------------------------------ +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFCSPHIGHO2_01_FULL_42_12 TaxID=1798377 RepID=A0A1F5Z5D4_9BACT +-dELAQVVRKAMQGTTGDYAIVIKNLKKGVSY-SQNENKLMHAASLYKSWLVTAVYEDIR +DGKLLEDQKLRESIPGLNNYFVIAPEELSSGMTVKQAVEQTITISHNYTALALLKNVGGY +DRVEKVLDEFGLANSTFK-------------IRPQTTAGDMAIFLEKLYKREIGDEQISE +KLIEVMSRNKL-NEGLPKYLPNKVTVAHKTGEIMT-YKHDAGIVYAPAGD-YLIVAMSDS +LS--TFGAEERIAQISRAVYDYf +>[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=Planctomycetes bacterium Pla108 TaxID=2528001 RepID=A0A5C6A2P2_9BACT +---LPNQIAELVESTPARVGLCVVHASGAPGF-GYREEEVFTQASAIKIPILGTLNRLAA +DGRLALSETLPVDPSDGVGGCGVLQNFLPGALALADLATLMIVLSDNVATNLLIERI-GF +DAVNELIEDHGSEATRLRRKMIDLEAR-KVGRENTATPRDAAVHMLRLAENANAGDPAAL +ATRRTLRLKKE--SPVTAALPKDLLLATKPGMLD-GLRTEWSLVQDEGGVDYAMALMADG +AD--DAVLEPLFRRLAAT----- +>[subseq from] serine hydrolase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI000490EB7F +-----------LDRVPGTVSAYLARLDTAPTW-IRHPATTHYAASTMKVAVLVALYRALE +AGRLASDTAVPVRNEFDSAQPGAAWDRLGGTAPLRWLAERMIVRSSNLATNLLLDQV-GL +PAVADVWARAGARHSVTGRGIEDFAA-RAGGITNLITAADLAALLRDLALGALATPESCT +AMLELLVAQEH-REDLAVGLPVGARIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCTTG +DDPDHSPDEDACQLIADISAR-- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6X6B3_9BACT +--DLVKRLNALCDGMPFQTSWYLKDLGSGAQA-DRLGAVPVPSASTRKTSILMSALAAVH +AGKLALDQKVTIEARYQDNDSGTFQFLTPGFITLRDALVMMIIVSDNTCTGLVVDLV-GL +DNVQRYCDAVGMKSTIHRYGMPKLTVGHSLEQVTTTTPQDQGLLLELILKGTQCTRELCR +LGLDILSWQRL-KTRLPSQLPLGTRVAHKTGTGPR-GYNDAGIVFKGDRALYILTAFTEN +VPAAFAAAYQIIGRMARMAWD-- +>[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8JXQ9_9BACT +----------------ARLGISAVLFDKRADI-SFNEDARFPMASVVKVPIAMLIASEIA +NGALSLHETITIHPRAFSPTNPIDRFYFATVYTVEQLMAFMIHASDNTATDAILNRLGGT +CAVMKFLFASDIEGISVKRTMHELLTHLIDSGEETCTPRAIVQLLKLLAMN-----PRYA +LVYSNMEHCAN-RQRIAVGLKEHKSLGHKTGSVG-AIANDVGIIHFNNGCFAALAVMTCH +STVRISVRDEQIATVTRTIVSQw +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. (strain ATCC 39149 / NRRL 15099 / SCC 1413) TaxID=219305 RepID=C4RKI1_MICS3 +------ELDARLNALPGTVSAYAGRVDAPPTW-TRRPDATHYAASTMKVAVLLALHRATE +AGTLDLDAPVEVRNESALPGAPRFWERESGHVPLRWLAERMIVRSSNLATNLCLRHV-GL +PAVADAWAIAGARHSVTGRGIEDFAAR-EAGITNLVTAADLAALLGGLAAGALASPAGCT +AMLDVLFAQEF-REDLAAGLPDGVRVAHKNGWVR-GVRHGAGVVYPPDAPPYVLVVCTTG +DPEAADDTCRLLADISARVW--- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora cremea TaxID=709881 RepID=A0A1N5YFF7_9ACTN +------DLDAHLDRVPGTVSAYVGRLDAPPTW-TRHADATHYAASTMKAAVLAALHRAAE +AGTLELDAPVPVVNQDSAQGAPRFWDRVGGTAPLRWLADRMIVRSSNLATNLVLGHV-GL +PAVAQVWALAGARHSVTGRGIEDFAAR-EAGITNLVTAHDLAALLGALATGQLASPAGCA +AMLDVLLAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVLPDDAPPYVIAVCTTT +DLEDEDDACRLIAHVSAQVWA-- +>[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2527 TaxID=2512215 RepID=A0A4R6KGT1_9ACTN +----------------GEFGVWLGRLDGVAVF-EHQAERTHYSASTMKLPVAIALMRKVA +AGELALDQPVIVRNDFASAEAPATWTKLGTPVELGWLATEMITLSSNLATDLVLECV-GV +DAANAVLTEYGSGRSAIRRGIDDRVAQ-AAGISNEMSPADLAAVLVAVGNDKT---AGGE +YVRDLLAGNQW-NGEIPAGVPAGTRVEHKNGWDTR-IRHDGGIVYPPDAEPFVLTVCTTS +ELPD-AEAQRLIASIATGAWN-- +>[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A359KPR0_9CHLR +--DIERDARALIDAFDGDAAFFAQNLLTGEEV-GFRADSVMPTASTIKLLVLAEVIRQAE +AGQFALDDPLPMISEDQSGGSGILKDLSPATLTIRDHATLMIALSDNTSTMALVRLA-GR +ARIEQAGQEWGMTATTLP-----IDRAPDGDARDYSTPRDIVHLLQLIATDALVSPAASA +TVRDILVTQQY-HDQIGRYLPYNIVVRSKSGFMTDSVRVDAGIIEISGVPRYVLCLMTEH +HP--------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Kocuria rosea TaxID=1275 RepID=A0A543P3Y4_KOCRO +------------------------------------------------------------ +----------------------------GLGLTVEQALDVMISWSDNASGAALGQWL-GW +EQVETFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSAA +LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG +WS--------------------- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6XRI2_9BACT +--DLVKRLNELCDAADFQASWYLKDLATGATA-DRLGDVPVPSASTRKISIMMAALAAVH +AGKLALDQKVTIDARYQDNDSGTFQHLTPGFITLRDAMVMMIIVSDNTCTGTVVELV-GL +ENVQRYTESVGLTGTVHRYGIPKVGPDNSLERVTTTTPNDQGLLLELILKGTQCTPALCR +LGLDILSWQRL-KTRLPSLLPLGTKVAHKTGTGHR-CYNDAGIIFKAARPLCVLTAYTVR +VPEAL------------------ +>[subseq from] serine hydrolase n=1 Tax=Saccharothrix sp. NRRL B-16314 TaxID=1463825 RepID=UPI000526923C +---AAAKVRALFADAGVTGRLHAVDLDHDREV-SVGADDPVVLASVFKVPLVVALHHS-- +--GLDLTRRVTLDHDRSTGPTGVGGMLDPVTMSLRDLAYLALTVSDNAAADALVDLI-GL +DEVDRTVRELHLGRTVVVHRARDFARALDPAQTNRGTPRDLTTLLRHVWQHD-----QCA +PIRRIMALQVW-PHRLASGFPDDVRVAGKTGTLPT-VRNEIGVVEYPDGGRYAVAVFTRS +ASFTLPAADAVVGTAARLAVEH- +>[subseq from] Beta-lactamase n=1 Tax=Microgenomates group bacterium GW2011_GWA1_48_10 TaxID=1618496 RepID=A0A0G1UCF5_9BACT +----ASAVEQALKQSQGKYYVYVKNLKSGETY-SLNDHTLLPAGSLYKAWLAVETLDLIR +QGKIEEDEVLSAKVADLNAWAGLSAEELTEGFTVREAVQRMIAVSHNYAAYLLTRKV-GE +TSVRTMLRKHGLTESSYKR--PPL-----------VTAFDMGLFFEKVYDDEFFSGESAT +ELKDIFAANEL-NLGLPKYLPKTVRVEHKTGELGR-YKHDCGIVYSSGGN-YVICAMSES +GDP--LGAQERIARISKNVYDYf +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. CNB394 TaxID=1169151 RepID=UPI00037FF65C +------DLDAHLDKVPGTVSAYVGRPGARQAW-TRRADATHYAASTMKLAVLVALFRAAE +AGRLGLDAPVPVRNSSALPGAPRFWDRVGGEVPLRWLAERMIIRSSNLATNICIGQV-GL +PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALASPAGCA +AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT +DLADSDDACRLIAHVSERV---- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Synergistetes bacterium HGW-Synergistetes-2 TaxID=2013843 RepID=A0A2N1QM40_9BACT +------AVRRETEKFPGTAGVVVSSLADGEGL-RHNADRVFSSASLIKLGVLYTLFVKQS +SGEIDLGECCEFSSLTAVEGGLLHRTRSGARLRLDDLALLMVSVSDNTAANMLIERL-GM +DAVNAEFKAMGLSGTVLGRKMLDFKAK-KEGRDNFTTAGDMALLLETLHSGERLPQETKN +RMMEILSAQKL-NTKLPGLIP--------------------------------------- +----------------------- +>[subseq from] hypothetical protein n=1 Tax=Kallotenue sp. CFH 73958 TaxID=2592335 RepID=UPI00128DA062 +--SLKTRLRQVALVHPGIQGVVVFEPSSARIV-ALNEDRPFMSASLAKLPVMLSLYKAAA +RGELSLEEEISILTSDVQGGSGVLHSYPAGYMTLRECASYMIKESDNTAWMMLERRL-GK +ARIVAELEALGAASTDYLA--------------YTTTPEDVLLMPGAVADPAYTSPELSR +EMLALMTDTAY-EDRLPQPLPEDVRVAHKMGSYGD-TFSDAGIVFPEDSDAYYIVVISDG +ATE--GVAHPAIRSMS------- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Curtissbacteria bacterium RIFCSPLOWO2_01_FULL_42_50 TaxID=1797730 RepID=A0A1F5H1T5_9BACT +---LKETVENVLIGTKGTYGVAIKNLKTGETY-YLNEHRIFESGSLYKIWVLATAFDQIK +NGTLKQDEVLSQDISVLNEDAGSAEITDGKILSVKNAIEQMIVTSHNYASLLLSERI-KL +SAVSAFLEKYNFDESTISEP--------P-----KTTPYDIALFFEKLYKGELANNENTE +EMLTIFKRQQL-NEGMPKYLPQNVKIAHKTGEIGW-AKHDAGIVFSDSGD-YIIVIMSES +DSP--RQAQENIALVSRAIYDYf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SID69 TaxID=2690323 RepID=A0A6B1N687_9ACTN +----EDQVRAIFERAGCTGTLLVQPLDEEREF-GLGADQLVVPASVMKVLVALAAETWFA +EGRLDPRERVVLGAAGRTPGPVGLSLLEDDVLSWRDMVVLMLTISDNPCTDALMNRL-GV +GTLNATAARLGLRNTVVRSDVRTLLDALAPGAGTRTTARDMVRLLRLLWSGQAGPAEACA +RVRAVMARQLT-RHRIASGFRTPVRVAAKSGGLAGIVRNEVGVVSYPDGRRYAAAVFTRS +RTADEAAINAAIGAATAHAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinocrispum wychmicini TaxID=1213861 RepID=A0A4R2JL68_9PSEU +--EVTEEITRRAEEVGVRVWLHATDIDGSRRI-GIDGAQPVVAASVFKVPVAVELARQAA +AGEIDLGERVTYVPGTGTMPYGLATYRHEVTISWHDLAILMIGISDNVATDLVVGKV-GL +PAVAELLARLGFTHTAVPHDCEGLFQILDPAQTCRTSAEEITRLLAMVWRDQAAPEQACA +DVRNWLGLQVW-PHRLRSGFHDGIRVSGKTGTLPM-VRNEAGVVEYPDGGRYAVGVFTQA +YDMQAPERDNFIGFAAARA---- +>[subseq from] Beta-lactamase class A n=1 Tax=Saccharothrix saharensis TaxID=571190 RepID=A0A543JKQ2_9PSEU +----AARVRAAFADAGVTGHLHAVDLDDPTRDlSVGADDPVVLASVFKIPLLVALHHSAH +----DLTRRITLDRDRSTGPTGIGGMLDPVTMSLRDLAYLAVTVSDNAAADALVDLI-GL +DAVNDTLDGLHLRHTLVVHRARDFMRALDPDHTNRGTARDLTTLLRHVWRHD-----DCA +PIRHAMARQVW-PHRLASGFPDDVRVAGKTGTLPT-VRNEIGVVEYPDGGRYAVAVFTRS +ASFTLPKADAVIGTAARLAVEH- +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus kochii TaxID=859143 RepID=A0A248TGQ6_9BACI +---------------------AAVHIETDEGIlSVNSHQVFSSASLIKVPILLTALREVE +KGRLHLEEEVKGG--LSVGGAGVLSALSPNPFTWKDILTLMMIVSDNSATNWIIDRL-EM +ETINRLIKSLNLEQTCLNRKMMDFQ-AIERGVNNLTSAYDMVQLLRVMKDKGRWIKDSYM +LMESIMAKQQF--TLLTAELEPNISYGSKSGSLQ-GVQHDCAYFCHENK--YVLAAVLTA +NLPNQMIGKQLISEIGMAI---- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora chaiyaphumensis TaxID=307119 RepID=A0A1C4YM09_9ACTN +------DLDAHLDKVPGTVSAYVGRLGAPPTW-TRHADATHYAASTMKVAVLVALHRAAE +AGRLDLDAPVPVRNSSALPGTPRFWARVGGEAPLRWLAERMIVRSSNLATNLCIGQV-GL +PALTEAWTLAGARHSVTGRGIEDFAA-RDAGIDNLVTAADLAALLGGLALGALASPAGCA +AMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWVR-GIRHGAGVVFPEDAPPYAVVVCTTT +DLADEDDACRLIAHVSAAVWA-- +>[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. BJA-103 TaxID=1911175 RepID=A0A2N8MT79_9PSEU +----IATINARAKEVGVRVRLHAAEVDGTRRI-GVDEHAPVVTASVFKVPIALELARQAA +DGGLDLGERISVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLIVARV-GK +EETEKTLRRLGFEHTTVPQDCAEVLGALQPAHTCATTAEEITRLLGLIWRDEAAPPAACA +DVRRWLDLQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA +VDSRVPERDSFIGFAAAQA---- +>[subseq from] serine hydrolase n=1 Tax=Bifidobacterium crudilactis TaxID=327277 RepID=UPI00068E20F0 +------------------------------------------------------------ +--------------------------HLNEAQSIDELLTQMITVSSNQAANDLISQLGGF +KLVNDIALKYGFTQTSLNDLLYDSGT--HDANRKTTSSQDCGRFMTAVYDGSLVSDDASQ +RMLSLLLAQTR-RSKIPAGLPDGTHVANKTGEIP-GTENDAALVYTTSGA-YVITVLTQD +IP-DSSNAQSGIREISRMTWE-- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. endophyte_N2 TaxID=2153485 RepID=UPI000FFE9E0D +-----DKVRAIFERAGCTGTLLVQPLDSEGEF-GLDPDQLAVPASVVKVLVALAAETWFA +EGRLDPRERVVLGAAERTPGTVGVSLFEDEVLSLRDMVVLMLTVSDNPCTDALMNRL-GV +DTLNATAARLGLRNTVVRSDLRTLLDALTPGAGTGTTARDMVRLLRLLWSGQAGPAAACA +RVRAVMGRQLT-RHRIASGFRAPVRVAAKSGGLAGIVRNEVGVVSYPDGRQYAAAVFTRS +RPADDAAINAAIGAATAHAV--- +>[subseq from] hypothetical protein n=1 Tax=Caulobacter sp. OV484 TaxID=1500308 RepID=UPI0006921ADF +-kRLQGRIEAIAARAPATLGVAVEDLTTRQLW-TFNGDQAFPLGPAARVPILAAVMAEAA +AGRLPPGELIAVRDVDLSPPSAVADAWPGRRWSVADLETLAL-HGDTTALDLLTKRIGGP +GAVNGWLDVQRIEGVSVDRYRRQIATARQGDARDTATPMAMARLLEAFAFRELGLAPDFD +GLLGH------DPGYLALALPKGARLAQAAGSAPTLGSQALAVVELKDGRRIAFVIFLTS +SAADAAKREALITDVGRAVLEEf +>[subseq from] Beta-lactamase n=3 Tax=Blautia TaxID=572511 RepID=A0A173TKY4_9FIRM +------------------------------------------------------------ +---------------------------------LNHLLELMITVSDNEAYNELMRRLGGC +QRVNQYLEREGYENTEVHHTLHPSSSASLGDGSNLTSVKDCGKLLERIYYGDCVSETASV +KMLKWLCRQQT-DWKIPAGIPKGIQIANKTGETDT-CQHDIAIVYAPSTT-YLLCVMSCE +LL-SENEGISGIQQLSAQVYEYf +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces rochei TaxID=1928 RepID=A0A510DF48_STRRO +---------EIFERAGCTGTLLVQPLDSEGEF-GLDADQLVVPASVVKVLVALAAETWFA +EGRLDPRERMVLGAARRTPGSVGVSLFEDEVLSLRDMVVLMLTISDNPCTDALMNRL-GV +DTLNATAARLGLRNTVVRSDLRTMLDALTPGAGTGTTARDMVRLLRLLWSGQAGPAAACA +RVRAVMGRQLT-RHRIASGFRAPVRVAAKSGGLAGIVRNEVGVVSYPDGRQYAAAVFTRS +RPADDAAINAAIGAATAHAV--- +>[subseq from] Beta-lactamase class A n=1 Tax=Actinoalloteichus hymeniacidonis TaxID=340345 RepID=A0A1D8C503_9PSEU +-----DEITDTFAAIGVTGRLHALSLTTDREV-GADPDTPVVLASVVKVLIALEYARQAT +AGLLDPTSMVWVRDGDRLGGTGTAGFLDDVALSLRDLAGSMMSVSDNTAADLLLDRI-GL +AALRSAIGELGLGATTVLGAPRDILAAFDPAGTTSSTPRDMTRLLSLIWRDLAGSAAACA +EVRRLMSAQLN-WHRLAAGFDDEVLVAAKSGSLPP-IRNEIGVITYPDGRGYAVSVFVEL +TGGRRPDVDVAIGRAARLAVD-- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. NBRC 110037 TaxID=1621261 RepID=UPI0007DB30B0 +------ELDAHLDKVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE +AGRLDLDAPVPVRNSSALPGAPRFWDRVGGDAPLRWLAERMIVRSSNLATNICIGQV-GL +PAVARAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALASPSACA +AMLDVLAAQEH-REDLAAGLPDGTRVAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT +DLADEDDACRLIAHVSARVW--- +>[subseq from] Serine hydrolase n=1 Tax=Mumia sp. Z350 TaxID=2585211 RepID=A0A5Q6RXQ6_9ACTN +-----------------------VATASGDVLaERNAGEAFYAASTIKVAPLVAAVRLLE +SGDLTLDTPLISRDTSQVPDAPDYGMAPAGEMPLREVLERMIIVSSNEATNMVIERV-GL +DAIASVLADAGAHDSRMSRQYGDQAAADAYGASNVVTAADLTALMGALVAGRLAGPESTR +FMVDLLARQE--DPLIAADVPDGVAWGSKSGSVE-AIRHDVAFVGTPGPDAVVMAVCTRG +YP--FEDANETIRALGGL----- +>[subseq from] Beta-lactamase class A-like protein n=2 Tax=candidate division WWE3 TaxID=422282 RepID=A0A0G1BP56_9BACT +---VETEFVELTKKLPGVYGLYIKDVGSGKEF-KYNDTTEFYSASLYKVPIAAAVLKEVE +AGKLKLDDTATYLPYDYASGTGVIGTYSHGILKISDILSELLKNSDNTAQNILLRTL-SY +KNVQDTFNA-----VVPDKNTSTFYRY------NLSTPGEISYVFEKLYFGDYLGTENKK +YLSDLMINTSF-EDRISAYLTDGLIFSHKIGSWPD-SWHDCGVVYTETKSELIVCLMSQR +A---------------------- +>[subseq from] Serine hydrolase n=2 Tax=Kocuria sp. 442 TaxID=2054280 RepID=A0A495A9K8_9MICC +------EVAEFLQSEDGAVSARVIDAPELPVF-SFHEEEVFPAASLYKLAVMMAFCREVD +HGVLEPSALVDLSPADRAQGPTGLAILEDTVISWRDLVRLMMSISDNAAAESVLRKV-GT +SRVHETLRLMGATRTEIRPTPPSGNGQYDPLSVSSTTASDLVTLLCAIWQDRAASAEQCA +FMRQVLSQQAWGHRFAEAFSYPGVTVAAKTGSFGS-LSHEAGVVSHPGEKSIAVAVLTRS +VRRQIPLSNKVVGQIARHCVRNy +>[subseq from] serine hydrolase n=1 Tax=Brachybacterium paraconglomeratum TaxID=173362 RepID=UPI00026C6E82 +--------------TEVRLAHCLLD-ADGAVLsASRADDPFYAASTIKLHVLLAVLRAAE +QGELDLDAELPATCTFTGAGEEFTPTHPEPGIALRDLATRMIDRSSNEATDQLLELV-GL +DAVAAVVGELGLTATRVERLIGDAS-ALERGLTNETSAADLARTMHHLVAGPGLSGDSHE +LALAALHAQTI--PIIATVLRDGVRWGSKSGWVD-GYRHDVAFVEDPAGGLRFLAVMTAG +LTED-EADARITAL--------- +>[subseq from] Peptidoglycan-binding protein n=1 Tax=Moorella sp. E306M TaxID=2572683 RepID=A0A4P6B9X0_9THEO +---LKKQIEEYLAGQPGTYGVFFKDLISGQSF-GINADTRLPAASTVKLPTVLFINHLVA +QGNLDWQQKLTYNSADYQGGSGILQFSVKDGLTLRTLTTMAITTSDNIAYNMLRNFV-GK +GSIASFMRSLGGQTVFP-------------DGQNLSTARDMATYVQAALDFAKVNPDGRR +LLDD-MANGIY-NEGIPLMIPAGVTVAHKEGFIW-GSPADVGVVFG--SRPFIITVLSQG +VE-DPDKGFANIATITKMMYDY- +>[subseq from] Beta-lactamase n=1 Tax=Clostridia bacterium 62_21 TaxID=1635276 RepID=A0A101FPF4_9FIRM +--ALRREMLAFIKQQPAAFGVYFADINANAVF-GIDENKPFPAASTVKLPVVLYLNTLAA +EGKVDWQEKVAYQPSDFQDGCGILRHRAKKGFSLRTLATLAITLSDNVAYRMLLRRL-GL +QRVAHFMRSLGGRVVFPR-------------GQNVTTAADMGVYLWGLLQFTARYGRLGE +RLLDDLANTIY-HVGLPGELPKRALVAHKEGEIA-GVANDVGIVFG--ERPFILAVLTRG +WA-DTSAGFAAIARLARLAWD-- +>[subseq from] serine hydrolase n=1 Tax=Streptococcus hyovaginalis TaxID=149015 RepID=UPI000A02A0E7 +------------------------------------------SASAIKLFILAAAHAKAT +RGELNLASNYTVKSSDIVEASLSLSGKVGKTFKLSDIASYMIQTSDNSATNIMIRQLGGI +AAVNAEIRRMGYNETTLNRYMR-IPSQINAGLENYISVHEAGDLIKNIVNGTLRDVNGEA +SMKQNLNKNVH-NYWLTNQTRTIATVFDKPGNDKYGVENDVAVITKNGR-GYVVALLTQE +SGSDSLTFSNLFSRFGLAVA--- +>[subseq from] Serine hydrolase n=1 Tax=Actinobacteria bacterium HGW-Actinobacteria-2 TaxID=2013647 RepID=A0A2N3GI37_9ACTN +--------------------ISLYAL-DGSIA-ELNAGAHHYAASTIKVAVLAALLRARA +TGLLAWDDTSEVHARDLAAQDPATWASLGSPVAWSVLAERMITVSSNIATDLIVERI-GI +TAVQDFLVEADLADLQFQRLIGDTAAQ-RAGHTNTVTADGLARLLVGLATDRWLPTSDSS +TAVEILSRQEY-RDGIGAGLPSGTWLASKSGWVP-GVRHDVALVRPPSAAPYALAICTTS +PVPD-AEAVALIAELSRITYQEw +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Streptomyces philanthi TaxID=371608 RepID=A0A367FC91_9ACTN +--------------------FLVRDLHTGDEV-GIEPDTELPVASLVKLPLAIATLERVR +RGELEGDRALEVSPGRITRPTGLTRFRHPARIAVDDLLYLATSLSDNTAADALFGLT-PP +ARVDALLEELGLTGIAVRHTMDELTDQLDVTRANTGTARAFTDLLQAVWTPSAVHPEVTA +RLRTLMGDNVMRHRLAPDFSSDSSSWSSKTGTLLN-LRHEVGVVQHADGAVYAVAALTES +RVATQPGAEALMAQVARELRD-- +>[subseq from] Uncharacterized protein n=1 Tax=Dehalococcoidia bacterium TaxID=2026734 RepID=A0A2E1ZCC7_9CHLR +--ALRSNVLEVIDEFSGTASVSANNLTTGDVL-DINEKEVLPALSAIKIGIMAELFFQIE +EGKYNLLDRVTINGSDLRGGTGVFREMETPLVTVKDLCMMMIVVSDNSCTWKLSSML-GV +DSINQRMRSLDMNEYSLNHDLPTAFDDMQGDAYSECSARDFTNLVTLIAKGELVSKTSSD +AMLDIMGRCQH-IEWLGRYLPPKVKLYNKLGAYLH-ARCDTGLIKSENSN-YVITVFASY +SKDEPHEGSRLIGKVSKVVYDAw +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. AMSO1212t TaxID=2650565 RepID=UPI00124BC5D7 +------ELDAHLDKVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE +AGRLDLDAPVPVRNSFDSAGAPRFWDRVGGEAALRWLAERMIIRSSNLATNICIGQV-GL +PAVAQAWALAGARHSVTGRGIEDFAAR-DSGVDNLVTAADLAALLGELALGALASPAGCA +AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPHDAPPYTIVVCTTT +DLADEDDACRLIAHVSERVW--- +>[subseq from] Beta-lactamase class A n=1 Tax=Granulicella pectinivorans TaxID=474950 RepID=A0A1I6M3U7_9BACT +--VLKEQLAVAAVAHRGKVALFATQLNTGRTV-ALDPDVPVQTASVIKLTILFEAMEQVK +AGKAKWDEKIVLAPGDGVGGSGILHFFDTPLLTLKDVLTMMVIVSDNTATNLAIDRL-GI +DAINGRIAWMGLKDTHLYKRIGKPATDQPKFGLGKTTAREMATVMERIGRGEAAGAEDCS +VALE-MLRNQFYRETIPRYLEKGSGIASKTGSLD-AVRADVAIVAGKSG-PMILSIFTYG +NVDHDNEGELTIAKLAKMIVTAw +>[subseq from] serine hydrolase n=1 Tax=Syntrophaceticus schinkii TaxID=499207 RepID=UPI000A079C7A +-qPLQEEVAKFTATLPGTYGIYLKDLASGEEF-GINEKTPIPPASTIKLPVVLYLYEQVA +AGKLDWRDRVSYNKNDYQGGAGDLQYVARHGYSLRCLATISITLSDNVAHNMLVRHL-GY +DNVMAFIKKLGPDTTRPF------GSA-------STTAKDMGAFVEEAYRFAERNPGQGG +RFLNDLAHTVY-HVGLPGELPPELVIPHKEGSII-GVATDAGIVFS--KRPYILVILSEG +IT-DEDTGFKNIAKISRIIYDH- +>[subseq from] serine hydrolase n=1 Tax=Sciscionella marina TaxID=508770 RepID=UPI0003793372 +----EDEIIARAEQVGLRVRMHARAIDGTGSF-GIGADEPVVTASVLKVPLAVELADQAE +REHCDLAEQITVPAGPKVPPYGLATFRHPVTLSLDALATLMIGISDNVATDLVFAKI-GK +PAVRALLDRLGLAGTVIEQDCAELLGALDPAQTCRSTAAEMTALLGMIWRDEAAGPGACA +DVRRWLGLQVW-PHRLRSGFHDEVRISGKTGTLPT-IRNEVGVVEYADGGRFAVAVFTEA +VDSQAPERDAFIGFAAARA---- +>[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7TST6_9BACT +---------------------------------------------------------QVE +EGRVDLGEV-TRPPMPRVRGGGVLQEVGDKVLTWRDLAVLMMGWSDNAATNVLIDRI-GM +DAVNRRLDSLGLRATRLRRHMMDLDAARRG-DENVSSPAEMRQLIEAMHAGHGLSGDRAR +DMMAVAAVPK--DSPFRVPLPESLVVADKPGSLE-AVRCVTAVVDLPGR-PYAVSIMTTY +LRRD-ADGEAAIREISAALYETf +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora inaquosa TaxID=2203716 RepID=A0A3N9X2Y3_9ACTN +------DLDAHLDRVPGTVSAYVGRLDAPPTW-TRHPNAAHYAASTMKVAVLAALHRAAE +AGTLDLDAPVPVVNDDSAQGAPRFWDRVGGSASLRWLADRMIVRSSNLATNLVLGHV-GL +PAVAEVWALAGARTSVTGRGIEDFAAR-EAGITNTVTAADLAALLGALATGKLAAPAACA +AMLDVLLAQEH-REDLAAGLPDGTRIAHKNGWVN-GVRHGAGVVLPDDAPPYLIAVCTTT +DLADEDDACLLLAHISAQVW--- +>[subseq from] Beta-lactamase n=1 Tax=Brachybacterium sp. SW0106-09 TaxID=1704590 RepID=A0A0M8KPR1_9MICO +--------------TEVRLAHCLLD-ADGAVLsASRADEPFYAASTIKLHLLLAVLRAAE +QGRLDLDAELPATRTFTGAGEEFTHPEPGTAIALRDLATRMIDRSSNEATDQLLELV-GL +DAIAVVVGELGLGATRVERLIGDAA-ALERGLTNETSAADLARTMHHLVAGPGLSGDSHE +LALAALCAQTI--PIIATVLRDGVRWGSKSGWVD-GYRHDVAYVEDPAGGRRILAVMTAG +LAED-EADARITAL--------- +>[subseq from] Uncharacterized protein n=1 Tax=Actinobacteria bacterium TaxID=1883427 RepID=A0A2N5KM43_9ACTN +---LRVDLEGAAGRHAGRYGVVAFDPDSGSGV-SLGGEQVFTAASVGKLPTLLALYRAAA +RGELDLDDKISILHEDYQGGTGVLHNFAPGTITLRECAYYLVNKSDNTAWAMLDRRL-GV +GTIQAEMAAIGAAGTDYG--------------MGTTTPEDVFLMLRKISDPSFTDGKLSG +EMISAMTDTAF-EDRIPASLPPDVRVAHKIGSYED-SYGDAGIVFYKDRRRYFIVVLSGG +TGE--GSARAAMQEISLTTYRH- +>[subseq from] serine hydrolase n=1 Tax=Brevibacterium epidermidis TaxID=1698 RepID=UPI000BF785B0 +--------GAELESAGLRARIIARDLGSNAEV-ALSPDGALPLASLVKVPIALAVLNRIK +AGELAADEQIRVDPAVNSTASPIGAARFRHPIAVEDLLTLAVCFSDNTAADALLDLV-PA +REVQRDLDELGLRGIDVRHRLDALVSQLDVSRANSGTARGLMDLLSELWRPGRVDPGSAA +RLRDLMSGNVVRHRIAPDLMSDSAQWSSKTGTLLH-LRHEIGVVDHADGQSIAVVVLSES +SIAVQPAAEAALGAAARALH--- +>[subseq from] serine hydrolase n=1 Tax=Prauserella endophytica TaxID=1592324 RepID=UPI0010BE8B01 +----AESIAEHWREVGATGHLLARNLDTGEHL-GFDVDTPVPLASVAKVPLALVVLDGIA +EGDLDPALAITIDPATKSLPSGVAAFRYPATLAVGDLLHLTLTVSDNASADALFDLV-GV +EHVDRRLRDWGCTGIRIRHRMHRMYETLDPAHANVGSATALVELLQRCWLDEVSRPDATA +ELRRLMALQVF-NQRLSSDLRADVRVSGKTGTFLH-LRHEIGVVTAESGDRVAIAALTRS +ARRAAHDIDLAIGAAARSAF--- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SID11233 TaxID=2706029 RepID=A0A6B3EXU0_9ACTN +------DIEEYFEQVGCEGALCVKPLEGDAGF-GLHADELVVPASVFKVQVALEVETAFA +EGRLDPCERVTLSTADRTPGPVGISLFSDDALSWRDMVVLMLTISDNHTTDALIRRV-GV +GALNGAATRLGLTGTVIESDLQAMLDALDPSQGTRTTPRDMVDLLRLIWTDQAGPAAACE +RVRAVMARQLT-RHRIASGFRLPVRVAAKSGSLVGVIRNEIGVISCPDGRRYAAAVFTRS +RPGSDAAISRAIGTVAA------ +>[subseq from] Uncharacterized protein n=2 Tax=Candidatus Woesebacteria TaxID=1752722 RepID=A0A1F8CN41_9BACT +-kKISEEFKNITKNLSGVYGLYVIRLNGEGAY-GIFDKEKFEAASLVKLPVLATLYKEAE +AGNIDLDTKYSLKNSDKITGSGSLSGKPAGTLTYRDLARFMGKQSDNTAYGIIKRIL-GD +AKINKEISDLGMTNTSLSD--------------HSTSPYDTGIFFEKLYKNQIVKEKYKN +EILDYLTDTIY-ENWLVAGIPEEIRVAHKYGRELH-VVNDAGVVFTK--EPFILVIMTKG +VV--EREADEFFPKLTKVIYD-- +>[subseq from] Beta-lactamase n=1 Tax=Verrucosispora maris (strain AB-18-032) TaxID=263358 RepID=F4FGJ5_VERMA +-----------LDEVPGTISVYAGRLDAPPTW-TRHTEVTHYAASTMKLAVLAAVHHTAE +TDGPDLDTPVEVTNRFTSARAGAAWNRLGQRVPLRWLAERMIVRSSNLATNLLIEQV-GL +PAVAEIWARVGARHSVTRRGIEDFAAR-EAGISNLVTAADLAALLDAVATGPIASPAGCA +AMLDVLCEQQI-RQDIAEGLPAGTRLAHKNGWVR-GVRHGAAVVFPDDAAPYLLVVCTTT +PLDDDADARELVADISAQVW--- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2E2TRK6_9BACT +--------------------------------------------------VMIEIYHRAS +QGQLALTDSILVKNKSIVDYSTYEYTQIGKQMTLFDLMNQMIISSSNLATNILIDEV-GA +KNVNASMQRLGAYNTEVLRGVEDQK-AYDLGLNNMTTAKDLMTIFKSIALPLGETTQDQI +AMIDVLKAQEF-NDIIPRFLPGDVQVAHKTGSIT-GLHHDAGIIYLPNGETYVLVLLSKN +LK-NFDQGTLTLAKISQLFYEH- +>[subseq from] serine hydrolase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI0003777469 +-----------LDRVPGTVSAYLARLDTAPTW-IRHPATTHYAASTMKVAVLVALYRALE +AGRLASDTAVPVRNEFESAQPGAAWDRLGGTAPLRWLAERMIVRSSNLATNLLLDQV-GL +PAVADVWARAGARHSVTGRGIEDFAA-RAGGITNLITAADLAALLRDLALGALATPESCT +AMLELLVAQEH-REDLAVGLPVGARIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCTTG +DDPDHSPDEDACQLIADISAR-- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535WLD3_9CHLR +----GSAVEKIVATSGAGIAVALIELGDPEAW-SLAGSQQFEAASTYKLPLLMWMAQLVA +AGQLDVAGEVCYLDSDWEDG-WFTDYTTGDCFTRQELAARVGLYSDNTAAHMLVRDLGGS +DSLNAFARAYGATGSMFYD-------------VNTTTAADLAALWEAEVRGEIGGSAAQA +WLYPLLSHTKF-ETGVSAGVPSSVTVVHKTGEVD-GVVHDAALVTSGPGGPYILVVMTDN +LGGD--AAFKAVAEVSAAVWQY- +>[subseq from] serine hydrolase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI00037A1216 +-----------LDRVPGTVSAYLARLDAAAPTwIRHPATTHYAASTMKVAVLVALYRALE +AGRLASDTAVPVRNEFDSAQPGAAWDRLGDTAPLRWLAERMIVRSSNLATNLLLDQV-GL +PAVADVWARAGARHSVTGRGIEDFAA-RAGGITNLITAADLAALLRDLALGALATPESCT +AMLELLVAQEH-RDDLAVGLPVGARIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCTTG +DDPDHSPDEDACQLIADISAR-- +>[subseq from] serine hydrolase n=1 Tax=Kocuria TaxID=57493 RepID=UPI00119D5A0E +--ELHDDVATMLHAADMTGAVSVRVIGSDRSF-NYRAGVRFPMASLYKLVVMAAFCQAVD +DGLIDPAAPVELVPETRVPGPTGLSICLDPVMSWRDLVRLMMTISDNTAGNAVLCAV-GR +DRVAHTLRRLGLLQTDIRPYLPATDLEYDPLLVSSTTTSDLVDLLSFIWEDHAATPSQCS +FMRHVLGQQAWGHRFAEVFTYPGVQIAAKTGSLA-ALSHEAGVISHPDEPPIAVAVLTQS +ARRTIPLSNTVVGQIARHCVRSy +>[subseq from] serine hydrolase n=1 Tax=Saccharothrix variisporea TaxID=543527 RepID=UPI000EB2D221 +----------------VTGRLHAVDLADPRQV-AVGADEPVVLASVFKLPLLVALYRS-- +--GIDLTRRVTLDPGDRSTPTGIGGLLDPVTMSLRDLAFLAITVSDNAAADALVDVV-GL +DEVNRVLRDLGLTRTAVVHRARDFMRALDPTRTNRGTAREMTSLLTHVFAEDVYEPIRRA +M-----SLQV-WPHRLASGFPDDVRVAGKTGTLPT-VRNEVGVVSYPDGGRYAVAVFTRS +ASFTLPAADAVIGTAARLAVEH- +>[subseq from] Serine hydrolase n=1 Tax=Dermacoccaceae bacterium C5-26 TaxID=1660198 RepID=A0A563DXJ5_9MICO +----------------------VLD-GAGSVLaQRAPDREFYAASTIKLAVLIAAMRAVD +AGRLALDQELTATHTFRSAGSEFGEGMPAEGISLHDVLWRMVAVSSNEATNMVVDLV-GL +DAVAEALAHCGARNSVMQRPIGDVEGR-SAGLTNRVTAGDLAALMRAVITGAAASPASTE +RMVSILEAQQI--PYLGKGLPTGTRFGSKSGWVD-AIQHDVAFVAPSGDETYVIAVCTRG +YE--EADATELLAGVSRLAWD-- +>[subseq from] serine hydrolase n=1 Tax=Kocuria rhizophila TaxID=72000 RepID=UPI0011A476A1 +--QLGREVAEILQSEDMTGAVSAIDAPELPVF-SFHEEEVFPAASLYKLAVMMAFCREVD +HGVLEPSALVDLSPADRAQGPTGLAILEDMVISWRDLVRLMMSISDNAAAEAVLRKV-GT +SRVHETLRLMGATRTEIRPTPPSGNGEYDPLSVSSTTASDLVTLLCAIWQDRAASAEQCA +FMRRVLSQQAWGHRFAEAFSYPGVTVAAKTGSFGS-LSHEAGVISHPGEKSIAVAVLTRS +VRRQIPLSNKVVGQIARHCVRNy +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8HBI2_9BACT +---LAARIDALIKPTGADVAVVFGRVDGAASL-AIGADEPFHAASTMKVPVMIELFREAD +AGTLSLDEPLPVRNESIVDGSVYQYKAIGTTMTLGQLCDAMITVSSNFAANLLIERL-GV +QNIRATVAKLGAGGMNVLRGVEDDK-AYAKGLNNTTTARALFTLLQAIARGKAVSPR--- +------------------------------------------------------------ +----------------------- +>[subseq from] Serine hydrolase n=1 Tax=Verrucosispora sp. SN26_14.1 TaxID=2527879 RepID=A0A4Q9C8T6_9ACTN +------------DREPGTISVYAGRLDAPPTW-TRHAEVTHYAASTMKLAVLAALHRTAE +TGRLDLDTPVPVRNRFTSAYSCVRWDRLGRQVPLRWLAERMIVRSSNLATNLLLDHV-GR +PAVAEVWAAAGARHSVTARGIEDLAAR-DAGITNLVTAADLAALLRAVAVGAIASPTACA +AMRDVLCAQQV-RQDIAEGLPAGTRLAHKNGWVR-GVRHGAAVVFPTDAPPYLLVVCTTT +PLPADAHARRLVADISA------ +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. L2 TaxID=2162665 RepID=UPI001011F91B +-----EAVAADWSALGVRGSFLARHIDTGEHL-GFDVDEVIPLASVVKVPLALVVLDRIA +RGELDAARPVTVDPASSVGPTGLAAFRHPATVAVGDLLLMMLSVSDNAAADALFDLV-PV +AEVDARLRDLGCEGLRVRHRMNHMYETLDPAHANTGSAAALVDLVERVWRDEVSRPEATA +ELRRLMGHQVF-TQRLAGELRADLRVSGKTGTFLH-LRHEVGVVEAASGDRVALAALTRA +DRRAAPDIDLAIAAAARRAFE-- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium varium TaxID=856 RepID=A0A414TUQ8_FUSVA +----EKRIREIINENSGVTGVIVRD-SFGKKI-MINEEVIFPSASIIKLFILMALNKD-- +----EYNKKIELKKEDKVGGCGILKVMEDGLLTIKDVAYLMICLSDNIATNILIDYI-GM +DKINESIKANGFRGTVLGRKMMDTEAR-KAGKDNFTTPEDVLKVLEILCGN------SD- +-DLDMLRNQAY-NNKIPLYYPREVDFAHKTGELMY-TEHDAGRLFFDNGW-VDIVVLTKD +LE-ENEDGIKINSLIGKLIFDNy +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. M71_S20 TaxID=592872 RepID=A0A498A8D9_9ACTN +------ELDAHLDGVPGTVSAYVGRVGASPTW-TRHADATHYAASTMKAAVLVALHRAAE +AGTLDLDAPVPVRNESALPGAPRFWERLGGGAPLRWLAHRMIVRSSNLATNLVIGHV-GL +PAVARVWDLAGARHSVTGRGIEDFAAR-EAGVTNLVTAADLAALLGALAAGALASPAGCA +AMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYAVVVCTTT +DLADEDDACRLIARVSAAAWD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Mycolicibacterium litorale TaxID=758802 RepID=A0A4V3H506_9MYCO +----EDQITAAFTDAGCRGWLRAERVGTGPVI-DISGDAPVVAASVYKVLVLIAAARAFD +AGRLDPHGTVRVVPGDCTPPTGISLFSDPVTLSWLDLARMMITLSDNAAADVLLAAV-EL +DTIDDVIEDLGLASTRVVGGTATLQRAFDPAYTTATSAADTNAMLTAIWTGRAASPESSQ +IMRTILSQQIW-PHRIRSAFPADVVVAGKTGTIGP-IRNEIAVVAFPEEIPVAVSVFTRA +ARSDLPIVDRAIGDTARIAV--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SM1 TaxID=402229 RepID=UPI000CD4BFD5 +-----------------------------REV-AVGADDAVVIASIFKILLVLEFARQAV +AGQLDPTERVRVTSADRLGGWGTAGCLDDVELSLRDLAYFAMSVSDNSAADLLLDRV-GL +DTVRLLAKELGLHRTCLVGGPRDLLVVLDPRHTTSSTPREITRLLRLIWTDAAGPPEACA +LVRDLMSKQVF-RHRLVSGFPDGVAVAAKTGTLP-GLHMEAGVARYPDGECYAIAVFART +HDLTRVTVDAAIGRAA------- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Eremiobacter sp. RRmetagenome_bin22 TaxID=2599629 RepID=A0A2W5XH40_9BACT +-------------------YAYVCDLDRGRFG-QWRSDENVYPASVIKVPIMAEAYRQYD +AGVLSPDAHVVITESNQTTTDQPTPLVTGYLATARELVELMITLSDNVATNQLMDVL-RR +ERVTDYMHELGLPTFVLGRKLEPLIEDPEMTGRNRLPPAEIGRLLALIADDRIVGAAQQR +AILN---RCKE-NRKLGPGLAPGDRFMHKTGETSD-LSHDAGILVTPEGRRSVIVLYTEF +EPDTANAAEASNAA--------- +>[subseq from] Iron-regulated ABC transporter membrane component SufB (Fragment) n=1 Tax=Candidatus Amesbacteria bacterium GW2011_GWA2_47_11 TaxID=1618357 RepID=A0A0G1RCN4_9BACT +-kEIADKLRKRVEGLSGEYAVGVYRLKTGENY-GFNQRVEMPAASIMKVPIMTAVLREAE +AGSLKLEDTYILKETDKRYGSGPLELLKAGTVTVERMLSVMGKNSDNTAPVVLARMI-GW +DKVTETLEKLGMTNSDFE--------------MNTTTAEDVVEMWAKLYEGGIVAQDHRE +MMWEWLTESIY-EERIPAGVPEWVHVVHKVGTDA-GVWADAGIVEC-------------- +----------------------- +>[subseq from] hypothetical protein n=1 Tax=Mycobacterium paragordonae TaxID=1389713 RepID=UPI0012E24259 +------------------------------------------------------------ +----------------------------------SQLCELMITMSSNLATNLLIKKL-GI +ENIRATVHLLGADGMNVLRGVED-NKAYDLGLNNTTTARALAILLTAIAEGKVVDPDASR +QMVEILKRQHI-NDGIPSGLDPTIPVAHKTGTLK-AIHHDAAIVYG--SQPFVLVILVRG +MA-DSKDSSALMADITRAFYR-- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6VP27_9BACT +--DLVKRLNALCDGMPFQTSWYLKDLGSGASA-DRLGAVPVPSASTRKISILMAALAAVH +AGKLVLDQKVTIEARHQDNDSGTFQHLTPGFITLRDALVMMIIVSDNACTGLVVELV-GL +ENVQRYCDALGMKGTIHRYGMPKLAVGHSLDQVTVTTPNDQGMLLELILKATQCTSQLCK +LGLDILSWQKL-KTRLPSQLPLGTRVAHKTGTGPR-GYNDAGIVFKGDRPLFILTAYTEN +VPAAFAAAYQIIGRMARMAWD-- +>[subseq from] Uncharacterized protein n=1 Tax=Streptomyces tsukubensis TaxID=83656 RepID=A0A5H2U075_9ACTN +--------ARSAAALPLVLAVAAIDVDDGRST-GVDDTAVLPVASAAKLLLLAEVARRLD +SGELDPAAAVAVTEDDVVHGTGLLVRLSRRDWTVEDLCWLTASVSDNTATNALLRLV-GP +ESTARLARSLSLGALTVHDRVRDVRGPDVPPVFATGTARALAGLVAHAARGSLVSPGASR +RLLSWMRSNTD-HTLAPALVSHDLLLANKTGTDP-GVRSDAGVFVGERRVAYAVVAHWDT +ALSTERAAVRAIRDVGRTLADY- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora palomenae TaxID=1461247 RepID=A0A561VFG3_9ACTN +-------LDARLERVPGTVSAYVGRLGAEPTW-TRRPDATHYAASTMKIAVLLALHRAAE +AGELDLDAPIPVVNGSAQPGTPRFWARVGGTAPLRWLADRMITRSSNLATNIVLGRV-GL +PAVARAWALAGARHSVTGRGIEDFAA-RDAGITNLVTAADLAALLGGLITGALASPAACA +AMTDVLLAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVLPDDAPPYVIVVCTTT +DLADEDDACRLIAEISATVWA-- +>[subseq from] serine hydrolase n=1 Tax=Veillonella caviae TaxID=248316 RepID=UPI000F8DEAE8 +--SLEKQLQEVICNVTGTISYVVTRLSDGEEVaAFKETMIHVGASMVKTLILEYVFHLAY +EGQLDLHDTIALSRSPRVAGAGVLQELMGNHFTYLELCRLMMVISDNWATNLLIQAL-GM +EYINARAHQLGLEHFEINRFMMDTLAV-QEGRDNYITALDMAKLLHHIYNLRYT--LEGH +EMWSILGRQQF-RDILPFHWGEDVVFHHKTGSLEN-VEHDAGILETMNGD-FCFVMLMSH +VRND--VAK-------------- +>[subseq from] Beta-lactamase class A-like protein n=1 Tax=Streptomyces tsukubensis (strain DSM 42081 / NBRC 108919 / NRRL 18488 / 9993) TaxID=1114943 RepID=I2MTP7_STRT9 +---------RSAAALPLVLAVAAIDVDDGRST-GVDDTAVLPVASAAKLLLLAEVARRLD +SGELDPAAAVAVTEDDVVHGTGLLVRLSRRDWTVEDLCWLTASVSDNTATNALLRLV-GP +ESTARLARSLSLGALTVHDRVRDVRGPDVPPVFATGTARALAGLVAHAARGSLVSPGASR +RLLSWMRSNTD-HTLAPALVSHDLLLANKTGTDP-GVRSDAGVFVGERRVAYAVVAHWDT +ALSTERAAVRAIRDVGRTLADY- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. AMSO12t TaxID=2650410 RepID=UPI00124B7F6A +------ELDAHLDGVPGTVSAYVGRVGAAPTW-TRHADATHYAASTMKAAVLVALHRAAE +AGALDLDAPVPVRNESALPGAPRFWERVGAEATLRWLAHRMIVRSSNLATNLVIGHV-GL +PAVARVWDLAGARHSVTGRGIEDFAAR-EAGVTNLVTAADLAALLGALAAGALASPAGCA +AMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYAVVVCTTT +DLEEDDDACRLIARVSAAAW--- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536DKI4_9CHLR +-------------DPDGDYAVVMEDLKSGARV-AVNESQVFPSASLYKLGVAWMVLRQVD +AGTLHLDGPLDIAEPDTIEPEPDGGVAAGDRPTVREALADMLTISSNAAAHAFLRTL-GR +VDFNREMQRIGLSQTRIPEDVDADG--SDGDAQAVTSAADIARLLRLMATSQQLSAAARD +VLSECLASGAP-PDALRETLPAGIDVLEKTGNLDD-ASNVGALLQSARG-TVILVVLDHG +VD--PGDARGVIAQAGHVAYK-- +>[subseq from] Serine hydrolase n=1 Tax=bacterium TMED144 TaxID=1986778 RepID=A0A3S5JYJ1_9BACT +-----KKIEILLNNFNGEVGFYFLHLEKGIDF-GINENKIFPSASLIKIPIMVQIFNXXE +NDNLNLDSLLFYDSSLINYDDSIARFKENETISINKLLTHMITFSDNHASLWLQNIAGGG +TKINEILNKYNFTKTKVNSRTLNREDQYLQYGWGQTTPKEMSKLMIEIKNGNIVSKKSSD +EMYRHLTRIYW-DDEALSQIPNHIQVASKQGAINK-SRSEVVLVNSLSGD-YVFCIITNN +QSDEENEGFVLIRKISRLLWNYy +>[subseq from] Uncharacterized protein n=1 Tax=Bacillus cereus HuA2-1 TaxID=1053201 RepID=J9B505_BACCE +----------------------------------------FMHPSTVKGLVTRVLLLQYP +--IKKLDEVITYTKDDLVEYSPSAEKHVDTGMTLREIAEATIRYSDNTAGNIL----DGP +KGFEKALKQIGNKVTMAACLEPALNEAIPRDIHDTSTAKTFATDLKAFTVRDALQTDKCK +IPTDWMRGNVT-E----------------------------------------------- +----------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora rhizosphaerae TaxID=568872 RepID=A0A1C6T684_9ACTN +------DLDAQLDKVPGTVSGYMARLGARPTW-TRLPDATHYAASTMKIAVLVALYRAAD +AGTLDLDTPIPVQNSSAQPGAPRFWDRVGGTAPLRWLAERMIVRSSNLATNIVLGQV-GL +PAVAEAWALGGARHSVTGRGIEDFAAR-EAGIDNLVTAADLAAVLGALAAGALASPASCA +AMLEVLFAQEH-REDLAAGLPEGTRIAHKNGWIR-GIRHGAGVVFPPDAPPYVIVVCTTT +ELADIDDACRLIADISARVWD-- +>[subseq from] serine hydrolase n=1 Tax=Amycolatopsis nigrescens TaxID=381445 RepID=UPI000380FEE3 +---VIETINDRAKEVGVRVRLHAAEIDGTRRL-GIDEHAPVVTASVFKVPVALELARQAA +EGGLDLGARITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLIVAHA-GK +EAVGETLRRLGLEHTTVVQDCREVLGALQPARTCATTAEETTRLLGLIWRDEAAPPTACA +DVRRWLELQVW-PHRLRSGFADGIRVSGKTGTLPS-VRNEVGVVEYPDGDRYAVGVFTDA +VDSRVPERDAFIGFAAAQAV--- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. ALFpr18c TaxID=1458665 RepID=UPI00124B62BE +------DLDAHLDRVPGTVSAYVGRLDAPPTW-TRHADATHYAASTMKVAVLAALHRAAE +SAALELDAHVPVVNEDSAQGAPRFWDRVGGTAPLRWLADRMIVRSSNLATNLLIGHV-GL +PALAEVWAVAGARNSVTGRGIEDFAAR-EAGITNTVTAADLAALLGALATGRLASPAACA +AMLDVLLAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVLPDDAPPYLIAVCTTT +DLEVEDDACRLLAHISAQVW--- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora inyonensis TaxID=47866 RepID=A0A1C6S3F6_9ACTN +--------DARLAAVPGTVSAHVGRPGADPTW-THAAHTPHYAASTMKVAVLAALYRAAD +AGTLDPDTAVPVQNDFPSADGPRFWQRLDRTAPLRWLAERMIVRSSNLATNILLGHV-GF +PAVADVWTLAGARHSVTRRGIEDSAA-RAAGITNLVTAADLAALLGALAVGAVATPTSCA +TMLDVLCAQEF-REDLPAGLPAGVPIAHKNGWVT-GVRHGVGVVLPHDAPPYVLAVCTTT +DLT-DTDACRLLADVSARVWA-- +>[subseq from] serine hydrolase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI00048EA4F2 +-----------LDRVPGTVSAYLARLDAAAPTwIRHPATTHYAASTMKVAVLVALYRALE +AGRLASDTAVPVRNEFDSAQPGAAWDRLGDTAPLRWLAERMIVRSSNLATNLLLDQV-GL +PAVADVWARAGARHSVTGRGIEDFAA-RAGGITNLITAADLAALLRDLALGALATPESCT +AMLELLVAQEH-REDLAVGLPVGARIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCTTG +DDPDHSPDEDACQLIADISAR-- +>[subseq from] serine hydrolase n=1 Tax=Halococcus sediminicola TaxID=1264579 RepID=UPI0006786E57 +----RDRVDAFGDRLDARFGAFFTTPGTFDVVhTVRPNERFTSASLIKLFVQYALYDRYD +GRLDALTEPYGLAAENRVAGTGLFHLLDDPDPTLEDLAMAMIGISDNAATNELIDHL-GR +EKINTVLNELGYADTRLGRKMMVTGGLPPGISENVTSPRDVASLVADTVHETTLSSVAYD +RLRVPLRHQHD-TSMVARYLPLGVDIEHKTGELTD-AVLDAGTLRIEDCDPLVFAVFLDE +LD-SPGEGTDVLASVGALVYD-- +>[subseq from] Uncharacterized protein n=1 Tax=Saccharomonospora glauca K62 TaxID=928724 RepID=I1D1I1_9PSEU +---VAESIAEHWREVGALGHLLARNLDTGEEL-GFDAETPVPLASVVKVPLALVVLDEIA +HGRLDAARPVTIEPARRSVPTGVSAFRHPATLAVGDLLHQTLSVSDNASGDALFDLV-GV +TTVDDRLREWGCSGIRVRHRLQRMYDTLDPAHGNVASAAALVELLHRIWLDRLAHPSATA +ELRRLMGLQVF-THRLSADLRDTVKVSGKTGSFLH-LRHEIGVVESESGDRVAIAALTRS +HRRAAHDIDLAIGAAARAAFE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora marina TaxID=307120 RepID=A0A1C4XTA8_9ACTN +------DLDAHLDKVPGTVSAYVGRPGARQAW-TRRADATHYAASTMKLAVLVALFRAAE +AGRLGLDAPVPVRNSSALPGAPRFWDRVGGEAPLRWLAERMIIRSSNLATNICIGQV-GL +PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALASPAGCA +AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT +DLADSDDACRLIAHVSEQVW--- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Cryosericum septentrionale TaxID=2290913 RepID=A0A398DYY4_9BACT +-------------------------------F-SQNSNLPFGAASIIKLPLLVCVAQLVE +LGELAWDRPIRLTVPA-PHGTGLLEHLDKSGWSVQDLCIMMMGVSDNMACNQLIEEI-GI +ERLNDVLQDLGYQATSIRRQMMDHE-TLARGIDNSVTAAEIADMLARLHAHRLVSNEASQ +RILDYLRMNQL-KDLIAWPLPGSAALAGKTGGMP-GSLLDAELVSVADGPTYSLCVFASG +FD-RAVQAKRLMVQVSERVYE-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RBG_13_45_10 TaxID=1798370 RepID=A0A1F5ZH49_9BACT +---LKHVIDKSLEGTTGVYGVVVINFQTGERY-AVNEHRVFVSASLYKLWVMATAFDEIQ +NGRLREDELLHQSIAVLNRISTRSAELTEGTLSVKNALEKMITISHNYAALLLSERV-KL +STVRRFLVNYGFTESALGE--P-----------TTTTAYDIALFFEKLYNGELADQEHTD +KMTDLLKRQML-NNKLAKYLPLDLPVAHKTGEIDL-YTHDAGITFGTNGD-YVIAVLSES +YFP--PGAAQRIADISKAVYDYf +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6TMP7_9BACT +--DLVTRMNALCDALPFQTSWYLKDLATGETA-NRLGDTPVPSASTRKISIMMAALKAVH +DGKLALDQKVTIDAKYQDNDSGTFQHLTPGFITFRDALVMMIIVSDNTCTGTVVDLV-GL +GEIQRFCESIGMSRTVHRFGIPRLGPDHSLDQVTTTTPSDQGLLLEMILRGVGSTPELCR +LGLDILSWQKL-KTRLPSLLPLGTKVAHKTGTGSR-GFMDAGIVFKDDHPLFILTAYTEH +VPAALPD---------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. TR1341 TaxID=2601266 RepID=UPI00138AD7CD +------KVRAIFERAGCTGTLLIQPLDGEGEF-GLDPDQLVVPASVVKVLVALAAETWFA +EGRLDPRERVVLGAAERTPGTVGVSLFEDEVLSLRDMVVLMLTVSDNPCTDALMNRL-GV +DTLNATAARLGLRNTVVRSDLRTLLDALTPGAGTGTTARDMVRLLRLLWSGQAGPAAACA +RVRAVMGRQLT-RHRIASGFRAPVRVAAKSGGLAGIVRNEVGVVSYPDGRQYAAAVFTRS +RPADDAAINAAIGAATAHAV--- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora globispora TaxID=1450148 RepID=A0A317KJL4_9ACTN +-------LDAHLDTVPGTVSAYVGRLGAGPTW-TRLPDATHYAASTMKLAVLVALHRAAE +AGRLDLDAPIPVRNAD-SADAPRFWDRVGGTAPLRWLAERMIIRSSNLATNVVLGQV-GL +PAVAEAWRLGGARHSVTGRGIEDFAA-RDAGITNLVTAADLAALLAAVAEGALASPESCA +AMLDVLLAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYAIVVCTTT +DLADDDDACRLVARISARVWE-- +>[subseq from] Peptidoglycan-binding LysM n=2 Tax=Clostridia TaxID=186801 RepID=A0A101EB56_9THEO +---LKQQIENYLAGQPGTYGVYFKDLISGRSF-GINADLPLPAASTVKLPAVLFINYLVD +RGNLDWQDKLTYRSDLHYQGSGILQFGVKDGYTLRTLTTLSITLSDNIAYNMLRHFV-GK +ETLAQFMRQLGGQTVFP------------N-GQNLSTARDMATYVQAALDFSQASPDGRR +LLDD-MANGIY-NEGIPAQIPVGITVAHKEGFIW-GSPGDVGVVFG--SRPFIVTVLSQG +VE-DPDQGFANIAAIAKMMYDY- +>[subseq from] Beta-lactamase class A n=1 Tax=Ureibacillus xyleni TaxID=614648 RepID=A0A285SXV6_9BACL +-eNLSKEINQYIKKFSGSIAIEYYDLTTGETY-QNNATKAYVAASTIKLPLAMYIMELAD +QEKIDLNQKLTYKKHHYVGGSGVLLGKVGSKYTIKDLLRKSMVFSDNIAYSMLKEKV-GE +KNYVKYMKKLGATYSSRN----AL---------SNTSAHDLILYVQQLYKLGQ-TTENGN +ELNKYLQQTIY-NETIPAGVK-GVKVAHKVGMIPYQLSHDVGIVY--DESPYAIAVMTKG +FS--YEKSKKIIADISRIVNKH- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. WMMA1996 TaxID=2039878 RepID=UPI000BF61961 +------DLDAHLDKVPGTVSAYVGRPGARPTW-TRRADTTHYAASTMKVAVLVALHRAAE +AGRLDLDAPLPVRNSSALPGAPRFWERVGGAAPLRWLAERMIIRSSNLATNICIGQV-GL +PAVAQAWALAGARHSVTGRGIEDFAA-RDAGIDNLVTAADLAALLGELALGALASPAGCA +AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTVVVCTTT +DLADEDDACRLIAHVSARVWD-- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Curtissbacteria bacterium RIFCSPHIGHO2_02_FULL_42_15 TaxID=1797716 RepID=A0A1F5GCQ9_9BACT +-------IVSNAQNQPGKWAIYIKDLKIQNTY-ELNSARVFGAASVYKLAVMYAAYDAIE +TSKLKKNDVLYADKTTLDQISGMQNQPPDQTYTVERALNLMITISDNYSALLLAERL-GW +ANMDKLMEQQGFAEINLVGA----NS-------PNITARATGTLLEKIYNKETVDEQSSQ +EMINLLLAQKV-NDRIPKYLPQDVKVAHKTGELET-IRNDAGIVYGKKGT--YIFVFLTD +TPQPLDATEQ------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis xylanica TaxID=589385 RepID=A0A1H3H181_9PSEU +---------ARAEEVGVQVWLHAEEVDGPGRI-GIGESEPVVTASVFKVPIALELARQAA +AGELDIAEPVTVQPGHPTPPYGLATFQHEVTMSWADLAVLMIGISDNVATDLILAKI-GI +PKVAELLKTLDLPNTIITSDCADLLAALDPKQNRGTTAEEITKLLSLIWRDEAAQPQACA +DVRRWLGLQVW-PHRLRSGFPDDVKVSGKTGTLPL-VRNEVGVVEYPDGGRYAVGVFTRA +VDARVPERDAFIGFAAA------ +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CT34 TaxID=1553907 RepID=UPI0005BB1E8C +-----ETIADDWAALGVRGSFLARHLDTGEQL-GFAVDEPVPLASVVKVPLALVVLDRIA +TGELDAARPVTVDPATSSVPTGLAAFRHPATVAVGDLLHLMLSVSDNAAADALLDLV-PV +ADVDARLRAWGCSGIRMRHRLNRMFETLDPAHANLGTAAALVDLLQRVWQDDIGHPEATA +ELRRLMGRQVF-TQRLASELRADLRLYGKTGTFLH-LRHEIGVVEAAGGDRVAMAALTRS +DRRA------------------- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ285 TaxID=2035250 RepID=A0A4Y9VD68_9ACTN +------DLDAHLDRVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE +AGRLDLDAPVPVRNSSALPGAPRFWDRVGGEAPLRWLAERMIIRSSNLATNICIGQV-GL +PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAAVLGELALGALASPAGCA +AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT +ELADEDDACRLIAHVSERVW--- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora terminaliae TaxID=1914461 RepID=UPI0012AED26C +-------LDAHLDTVPGTVSAYVGRLGAPPTW-TRHADATHYAASTMKVAVLVALHRTAE +AGRLDLDAPVPVRNSSALPGTPRFWARVGGEAPLRWLAERMIVRSSNLATNLCIAHV-GL +PAVAEAWTLAGARHSVTGRGIEDFAA-RDAGIDNLVTAADLAALLGGLARGALASPAGCA +AMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYAVVVCTTT +DLEDEDDACRLIAHVSAAVWA-- +>[subseq from] Beta-lactamase n=1 Tax=Nocardioides sp. Root151 TaxID=1736475 RepID=A0A0Q7ZQ01_9ACTN +--EVAHEIRQAWSEAGLRGAFSARNLDTGEEL-GFEPDLPFPLASVSKVPLALVVLDLIA +CGELDAERQVTLDPKDRTPPTGISSFRHPTSVAVEDLVLLMLTVSDNAAADALFEIT-PP +AAVADRLAAWGCTGIQVRHPIRTLYDALDSGTATCGTSRGLVDLMDKVWNDRVSVPTATA +RLRELLGGQVN-GARLASGLSSDVRVHSKTGTFLN-LRHEAGTICSSAGDRIAVAALTAS +TVPSQPEAERAIALAGRAAFE-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sediminicola TaxID=946078 RepID=A0A1A9B8X6_9ACTN +------DLDAHLDKVPGTVSAYVGRPGARPTW-TRRADTTHYAASTMKVAVLVALHRAAE +AGRLDLDAPLPVRNSSALPGAPRFWERVGGAAPLRWLAERMIVRSSNLATNICIGQV-GL +PAVAQAWALAGARHSVTGRGIEDFAA-RDAGIDNLVTAADLAALLGELALGTLASPAGCA +AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTVVVCTTT +DLADEDDACRLIAHVSARVWD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ309 TaxID=2035247 RepID=A0A2N3Z1Y7_9ACTN +-----------LDEVPGTVSAYVARVGAAPAW-TRHADTTHYAASTMKAAVLVALHRAAE +AGTLDLDAPVPVRNESALPGAPRFWERVGADGTLRWLAHRMIVRSSNLATNLVIDHV-GL +PAVARVWDLAGARHSVTGRGIEDFAAR-EAGVTNLVTAADLAALLGALAAGALASPAGCA +AMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYAVVVCTTT +DLEEDDDACRLIARVSAAAW--- +>[subseq from] Beta-lactamase class A n=1 Tax=Kitasatospora sp. SolWspMP-SS2h TaxID=1305729 RepID=A0A327TUH1_9ACTN +-----------------------------REF-GFRADEPSVPASVVKVQVALEAETWFA +EGRLDPGERVTLSAADRTFGPTGTSLFEDDALSWRDMVVLMLTISDNHTTDVLLRRI-GV +DAVNATAERLGLTGTALESDLRAMLDALDPSRGTRTTPRDMAELLRLIWTDRAGPAAACA +RVRTLMGRQLT-RHRIASGFRPPVRVAAKSGGLLGVVRNEVGVISHPDGRRYAAAVFTRS +RPSDETAINAAIGTATAR----- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536LK19_9CHLR +---LQAAIETALAGREGSYSVVVHNLANGRGA-SLNADKVYYAASLYKLEVLLEVFRQRD +AGQLDFGGLLTLEKKYIDLTLDALEILENDEVTVRDAVRAMTIVSDTPTAALLQDTV-GA +GRIDETLASLGLGSTQSANRELP------------TSARDMARLLTAIAAGEGVNAGSRN +EMLSLLEQEGY-RAGVIAGVPPDAAVAHKTGSYSD-ATHDVALVWGPKG-PYVIAVLTDR +SY-----DWDAIREVSRAVWDYf +>[subseq from] Beta-lactamase class A n=1 Tax=Plantactinospora sp. CNZ320 TaxID=2035246 RepID=A0A2N3S6Q0_9ACTN +-----------LAAVPGTVSVYAGRLGRRPAY-TRLPDTPHYAASTMKVAVLAALHRAAE +AGEVELDAPVPVVNE-FDSASPGAWARVGGSAPLRWLAERMVVRSSNLATNLVIRHV-GL +PAVARVWADSGARHSHTRRGIEDFAA-RDAGLDNLVTAADLAGLLGGIARSRLASPGACA +AMLDVLLAQER-GEDLAAGLPPGTRIAHKDGWVR-GVRHGAGVVFPDDAPPYAVVVCTSA +PPDTEARARQLVTRVSALVW--- +>[subseq from] serine hydrolase n=1 Tax=Kocuria rosea TaxID=1275 RepID=UPI000D644033 +---LAADLEELAAEVPGELGVVLLDPEGGEVV-ARNADRPFTSASLYKLFLAHAVLDRAD +RGALALSDVV-----------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW +EQVETFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSAA +LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG +WS--------------------- +>[subseq from] serine hydrolase n=1 Tax=Brevibacterium linens TaxID=1703 RepID=UPI00057C8B02 +--------GAELESAGLRARIIARDLGSNAEV-ALSPDGALPLASLVKVPIALAVLNRIK +AGELAADEQIRVDPAVNSTASPIGAARFRHPIAVEDLLTLAVCFSDNTAADALLDIV-PA +RDVQRDLEDMGLRGMDVRHRLDALESQLDVSRANSGTARSLMDLLAELWRPERVDPGVAA +RLRELMSGNVVRHRIAPDLMSDSAQWSSKTGTLLH-LRHEIGVVDHADGQSIAVVVLSES +SNAVQPAAEAALGAAARALH--- +>[subseq from] Beta-lactamase class A n=2 Tax=Ruminiclostridium cellobioparum TaxID=29355 RepID=S0FPH9_RUMCE +--ELKKIITDYTSKLSGRYGVTYIDLATGEMV-NVSDQVEYIAASTSKLPINMVLFKDIE +AGKVSLEDKLVYKEEDLEYGTGIIQNSPYGTYTVRETSKLAIRKSDNCGVNMIIRQV-GI +ENVRKYLTDLGGKVYY--------------GKTHRSCPYDMALVARDLYSHYLDNEAVYG +ELINNLENTDW-NDRISAKLT-GVKVAHKIGNQTK-TANDVGIVFG--KHPYVLSVMTED +VD--FGTACNNIAALSKKI---- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6YIM2_9BACT +--DLVKNLNELCERAEFEVSWYLKDLASGVAA-DRRGKVAVPSASTRKTSIMMAALAAVH +AGKLSLDQKVTIDKRFQDNDSGTFQHLTPGFISLRDAMVMMIIVSDNTCTAHVVDLV-GL +SNVQRYTESVGLTGTVHRYGIPKAAPDSSLDRVTTTTANDQGLLLELILKGTQCTTALCR +LGLDILSWQKL-KTRLPSLLPLGTKVAHKTGTGHR-CYNDAGIIFKGDRPICILTAYTVD +VPDA------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Desulforudis sp. TaxID=2093368 RepID=A0A3A6MPH3_9FIRM +-tRLQAELQAKLAKAPGEYGLCLIDLASRSRF-GINEEKIFHAASTVKIPINLYLAQKFA +NREIDPAEYLTYEAVHYEGGTGYLHTHSFGNYQIARLSRDSIVYSDNVATNIILSRL-GR +KQVKDFMRSLGAEAVEND--------------RNTTCPKDMALMMEALVLFADEHPAEGG +LLLEYLRTSVF-RDGIPAAALDTVPVANKIGFWASGTYNDVAYVEHPAR-PYVLAIYSKD +TP-GREAAFAHIRRLASVVYSY- +>[subseq from] serine hydrolase n=1 Tax=Actinopolymorpha alba TaxID=533267 RepID=UPI000382EC66 +----AESVAADWERVGARGHLLARNIDTGEEF-GFDADTLVPLASVIKVAIALAVLDRTA +AGTLDPAYQVTISPGTRSLPTGLGAFRYPATLAVGDLVHQMLTVSDNAAGDTLLDLV-GI +DEVNRSLRAWNCPGIRIRHRLHRYYEILDTAHANVGSATALVDLLQRVWLDQISQPSATA +ELRRIMALQVF-TQRLSSDLRDTVRVSGKTGTFLH-LRHEIGVVETDSDDRIVIAALTRS +TRRAAADIDLAIGAAARSAF--- +>[subseq from] serine hydrolase n=1 Tax=Nocardiopsis sp. FIRDI 009 TaxID=714197 RepID=UPI000E21D454 +--ALVRELRQELDEGGLRGSFLVRDLASGREV-GIEPDLEYPTSSVVKVPLAIAVLELVR +RGELDGAAPVEVRPEDVGVVGPFGLSRFRHPIAVEDLIYLSLCLSDNKATNLLFERV-PP +EEVARVLRTFGIGGVTVRHAIRELREQLDVTRTNTASARACVDLLAALWTPSRIPPEVAA +RVRELMGANMLRHRLAPDFTSDSTRWSSKTGTLLH-LRHEIGVVEHEDGQAFAVAALTES +RVVVQPEADALMARVARALRDH- +>[subseq from] Uncharacterized protein n=1 Tax=Brevibacterium linens TaxID=1703 RepID=A0A0B9A173_BRELN +--------GAELESAGLRARIIARDLGSNAEV-ALSPDGALPLASLVKVPIALAVLNRIK +AGELAADEQIRVDPAVNSTASPIGAARFRHPIAVEDLLTLAVCFSDNTAADALLDIV-PA +RDVQRDLEDMGLRGMDVRHRLDALESQLDVSRANSGTARSLMDLLAELWRPERVDPGVAA +RLRELMSGNVVRHRIAPDLMSDSAQWSSKTGTLLH-LRHEIGVVDHADGQSIAVVVLSES +SNAVQPAAEAALGAAARALH--- +>[subseq from] serine hydrolase n=1 Tax=Bifidobacterium goeldii TaxID=2306975 RepID=UPI000F7F1817 +------------------------------------------------------------ +-----------------------------DTATIDADLTQMITVSSNDAANRLLAVIGGT +QGTAQAIATVTDTAQRYGFTTQELRAASGNTVENWTSSLDCGRFLMKAYNGELVSQNASK +RMTDLLLGQTR-RSKIPAGVPAGIQVANKTGELA-AVQNDVAIVYG--THPYVLAVMANN +VDGSA---VTRISSLSAAVYQAf +>[subseq from] Serine hydrolase n=1 Tax=Nocardiopsis sinuspersici TaxID=501010 RepID=A0A1V3C8I4_9ACTN +------------------VRVHAREIDGTGQV-GRLADEPVVLASVAKVLIALEFARQAS +TGLVDPTERVVVRRDDRLGGWGTADFADDVELSLRDCALLAMTISDNTAADLIVDRV-GV +EPVHLLAVELGLERTRFTGGPRALLHARDPSRTTSSTPADITRLLRLVWTDAAAPPKACA +FVRDLMARQLV-RTRIASGFGPDVRVSVKSGTLP-GLRMEAGVVEYPDGGRYAVAVCAVG +PDRTALEADMALGRAAREAVE-- +>[subseq from] hypothetical protein n=1 Tax=Faecalicoccus pleomorphus TaxID=1323 RepID=UPI00143113B7 +------------------------------------------------------------ +------------------------------------YLEAMIIHSDNTSYNILLEKLGGA +SKVTAFCKKLGLTRTEIHHGLEPGDGYFSDGQNNTTCPEDVGQFFEMLYHSEIVSDSSCK +DMLNLLKQCAD-DTGMVAGLSEDTECAHKSGWAD-AYYLDGGIIYTEHKD-YILVVFSDS +AYQTPA----------------- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces achromogenes TaxID=67255 RepID=UPI0004C87584 +---VAEAIAEDWAALGVRGSFLARNLDTGEQL-GFDTDEPVPLASVAKVPLALVVLDRIA +AGELDTARPVTVDPRTSSVPTGLAAFRHPATVAVGDLLLLMLSVSDNAAADALFDLV-PA +AQADARLRAWGCDGIRVRHRMNHLYETLDPAHANAGTAAALVGLLQRVWRDEIASPPATA +ELRRLMGHQVF-TQRLAGELRADLRWSGKTGTFLH-LRHEIGVVEADSGDRVAMAALTRA +TRRAAPDIDLAIGAA-------- +>[subseq from] Serine hydrolase (Fragment) n=1 Tax=Verrucomicrobiales bacterium TaxID=2026801 RepID=A0A3D3P151_9BACT +-----------------------------------NVDEFSPAASMIKIPILASILDKVE +RGKIGYQDKLTYTKDRRFPGEDLLGSFANNQLTLKKLVFLMITTSDNTASLWCQELAGTG +TTINTWLKQKGFLHTRLNSRTPGRADARDRYGWGQTTPREMAQLLIRIRNRKLVSPAADE +EMARVMGRIYW-DGEALSSVPPSISTMSKQGAVN-ASRSEVVLVHAPHGD-YVFCLITKN +QKQHDNKGFELLRDISRILWEHf +>[subseq from] serine hydrolase n=1 Tax=Phycicoccus jejuensis TaxID=367299 RepID=UPI00068C4612 +--NLREALRADLADAGLRASLLARNLGTGREV-AIDADVLTPAASLAKLPLALAVLTRVD +DGRLDGGARIEVPPGQPHEATPGLGRLRHPAVAVEDLVGLALTVSDNAAADALLRLV-PP +AEVTADLDALGVAPMVVRHPFAELSDQLDVARTNVVTARSTADLLERVWTGRGLRPAVAE +RLREHLHGNALRHRLAPDLASDDARWASKTGSLLN-LRHEAGVVEHADGTLVVVVALSTS +SVSVQPAADASLGAAARAVHDH- +>[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. 6K102 TaxID=2530382 RepID=A0A4R5E523_9ACTN +-----RRLNALCDTQPYVTGWCLIGLPDGGVRaDRHGARAFPAASTRKVAVMMAALRAVH +RGELDLDARLSIDGRYRDRFTGLLQ-HLDPGLSLRDAVTLMIIQSDNLSTAHVLDLV-GL +DAVNDLCASAGLTGTRHRHLIPRLAPDHPVDASNVTTPGDQARLLELIARGSAAEPEANR +LLLDVLCHQQF-RDTLPALLPYGTKVAHKSGAGWR-DVSDGGVFFGDDGPRYVLAVYTDE +L---------------------- +>[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535M9N2_9CHLR +---LAAQLSGVQSASGARIAVSLIELGNPQSW-SFHGDDPFVAASTYKLPLLMAEAEAIA +AGQEQPGDQLCYSAEDWEDG--WFQDYSAGAYSREDLASRIGQDSDNTAAHMLVRFLGGG +SALNAYAAGHGASESAFY-------------DPNTTTASDLARLMAAEATGAAGGASAQQ +WLYPLLTHTAF-EQGIPAGVPATVTVVHKTGELDS-VTNDVALVLGGADGPHVVAICVDG +PGSD--AGFSVIAQVASLIWE-- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A349VQ10_9FIRM +--ALQTKITDYLASQNGRYGVYYINMNNGETL-GVKETQPIVAASSIKIAYNTYLYEKAA +SGEISLDEKMKYNAAAYPQGTGNIQNSADGTYTVQEVSHRSITISDNCGTNMVLRRLGGE +DAVNNYLKTISAVDYRSKVEYTDYAGN-TQNGRRRTSAIDLAKYAEHLYKDYRGNETHYQ +PLIDDLCNTEY-NWGVPAGVPGTVKVAHKVGFNSYGANNDVAIVFGSE--DYVLCVMTES +GD--GQKAQDIIGEVSKMIYEY- +>[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A359JKT7_9FIRM +--ALQTKITDYLASQNGRYGVYYINMNNGETL-GVKETQPIVAASSIKIAYNTYLYEKAA +SGEISLDEKMKYNAAAYPQGTGNIQNSADGTYTVQEVSHRSITISDNCGTNMVLRRLGGE +DAVNNYLKTISAVDYRSKVEYTDYAGN-TQNGRRRTSAIDLAKYAEHLYKDYRGNETHYQ +PLIDDLCNTEY-NWGVPAGVPGTVKVAHKVGFNSYGANNDVAIVFGSE--DYVLCVMTES +GD--GQKAQDIIGEVSKMIYEY- +>[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium nucleatum CTI-6 TaxID=1316587 RepID=U7TNV0_FUSNU +-tEWKKEIEKIISQVEGKVCINFYDLNKNDGF-SINGNEKVLSASMIKLLILAELMKKKS +ENKFSLSDTIMIANSMKTGGDGVLKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM +ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ +LIKNM------------------------------------------------------- +----------------------- +>[subseq from] Carbepenem-hydrolyzing beta-lactamase KPC n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2P1BNC2_KLEPN +----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFRAFLLPLCWLAAS +SRPACWT-HPSVTAK--CAGSVVTHKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP +AGLTAFMRSIGDTTFRLDRWE--------------------------------------- +------------------------------------------------------------ +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora parva TaxID=1464048 RepID=UPI0004C0899C +------DLDAHLDRVPGTVSAYVGRLDAPPTW-TRHANAAHYAASTMKVAVLAALHRAAE +AGTLDLDAPVPVVNDDSAQGAPRFWDRIGATASLRWLADRMIVRSSNLATNLVLGHV-GL +PAVAEVWALAGARTSVTGRGIEDFAA-RDAGITNTVTAADLAALLGALAIGALASPAACA +TMLDVLLAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVLPDDAPPYVIAVCTTT +DLADEDDACLLLAHISAQV---- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / BCRC 12538 / CBS 129.76 / JCM 10878 / NBRC 16125 / NRRL B-16091 / INA 9442) TaxID=644283 RepID=D9T565_MICAI +------DLDAHLDRVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE +AGRLDLDAPVPVRNSFDSAGVPRFWDRVGGEAPLRWLAERMIIRSSNLATNICIGQV-GL +PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAAVLGELALGRLASPAGCA +AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT +DLADEDDACRLIAHVSERVW--- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ299 TaxID=2035244 RepID=A0A2G6XSA0_9ACTN +-------LDAHLDKVPGTVSAYVGRPDAPPTW-TRHPDAAHYAASTMKVAVLAALHRAAE +AGTLDLDAPVPVLNEDSAQGAPRFWDRLGGTASLRWLADRMIVRSSNLATNLVIGHV-GL +PAVAEVWAGTGARTSVTGRGIEDFAAR-EAGITNTVTAADLAALLGALATGALASPAGCT +AMLDVLLAQEH-REDLAAGLPEGTRIAHKSGWVR-GVRHGAGLVLPDDAPPYLITVCTTT +TTEVEDDACRLLAHIS------- +>[subseq from] Class A beta-lactamase n=1 Tax=Veillonella sp. ICM51a TaxID=936591 RepID=X8H3D4_9FIRM +---LEIQLAALLDTLDATVSYMVTRLNEGEEA-TIVASSKHTGASMVKTLILEYVFHLAA +QEQLDLNDTIALSRSPRVEGAGALMELVGNHFSYLELCRLMMVLSDNWATNLLMQAL-GM +ENINARAEQLGLEHFEINRMMMDFTAA-KENRENYITAMDMAVLLHHIYEL--RHTIYGH +EMWNILGRQQF-RDILPFHWGEDVIFHHKTGSLDC-VEHDAGIIETMNGD-FCFVLLMSH +LDND--KAKQLGA---------- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora globispora TaxID=1450148 RepID=A0A3N9VG76_9ACTN +-------LDAHLDTVPGTVSAYVGRLGAGPTW-TRLPDATHYAASTMKLAVLVALHRAAE +AGRLDLDAPIPVRNAD-SADAPRFWDRVGGTAPLRWLAERMIIRSSNLATNVVLGQV-GL +PAVAEAWRLGGARHSVTGRGIEDFAA-RDAGITNLVTAADLAALLAAVAEGPLASPESCA +AMLDVLLAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYAIVVCTTT +DLADDDDACRLVARISARVWE-- +>[subseq from] Uncharacterized protein n=1 Tax=Kocuria sp. SM24M-10 TaxID=1660349 RepID=A0A0J1EZD2_9MICC +--TLADDLEQLAVGVPGELGLVLLGPDGDELA-SRAADRPFTSASFYKLFVAHAVLERVD +RGELALDDPVP-----------------GSALTVGTALAAMISWSDNPSGAALGRWL-GW +AELEEFAHRHGFPATTFDPDTGDADRV-----AMTTTPADVAALLERLRRGELLSPASTA +LFRQLLEDQQL-DYALPSGFSPGTAFAHKTGLLED-VSHDAGLLTLDGRE-HVVVVMTD- +----------------------- +>[subseq from] Beta-lactamase n=3 Tax=Candidatus Gottesmanbacteria TaxID=1752720 RepID=A0A0G1IQ35_9BACT +----EEIVPKTLSGNEGTYGIVIKNLQTEETY-LSNEHHKFQSGSLYKLWVMATAFDQIK +NGLLKLEQEIPILNEKFRIATADAERIEGKILSVADALNQMITLSDNYAALLLSEKV-RL +SNVAKFLNTHGFSESKVGTDG-----SIP-----ITTPSDIAEFFTKLYEGTLIDKEYDK +KILDLLKQQKL-NNKIPKNLPENIAVAHKTGEFNS-FTHDGGIVYTPYGD-YIIVILSES +QD--PLNTEEAIADLSKAVYGHf +>[subseq from] Beta-lactamase n=2 Tax=Patescibacteria group TaxID=1783273 RepID=A0A0G1FTC2_9BACT +----EEIVPKTLSGNEGTYGIVIKNLQTEETY-LSNEHHKFQSGSLYKLWVMATAFDQIK +NGLLKLEQEIPILNEKFRIATADAERIEGKILSVADALNQMITLSDNYAALLLSEKV-RL +SNVAKFLNTHGFSESKVGTDG-----SIP-----ITTPSDIAEFFTKLYEGTLIDKEYDK +KILDLLKQQKL-NNKIPKNLPENIAVAHKTGEFNS-FTHDGGIVYTPYGD-YIIVILSES +QD--PLNTEEAIADLSKAVYGHf +>[subseq from] Peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 n=1 Tax=Ruminiclostridium papyrosolvens DSM 2782 TaxID=588581 RepID=F1TI99_9FIRM +---LKKIITDYTAGLSGKYGVTFIDLATGEMV-NVRDTDRYIAASTSKLPINVLLYKNIE +SGKVKLDDMLTYQKEDVEPGTGIIQKSAGTQYTVRETSKLAVTKSDNCGVNMIIRLL-DI +QNVRQYLVDLGGKVY--------------YDNHHRSCPYDMALVAQDLYKHYLKNEAVYG +ELINNLENTDW-HDRIDAQLT-GVKVAHKIGNQVK-TANDVGIVFAS--HPYVLSIMTDN +VD--------------------- +>[subseq from] serine hydrolase n=1 Tax=Candidatus Cryosericum hinesii TaxID=2290915 RepID=UPI001402C29A +---------------------------------SQNSNLPFGAASIIKLPVLVCVAQLVE +LGDLVWDRPIRLTVAAP-HGTGLLEYLDRSRWSVQDLCIMMMGVSDNMACNQLIEEI-GI +ERLNDVLHDLGYEATSIRRRMMDHE-MLARGIDNSVTAADIADMLARLYAHRLVSNEASQ +RMLGYLRMNQL-KDLIAWTLPGSAALAGKTGGMP-GSLLDAELVSVADGPTYSLCVFASG +FD-RAVQAKRLMTEVSERVYE-- +>[subseq from] serine hydrolase n=1 Tax=Brevibacterium luteolum TaxID=199591 RepID=UPI001404B095 +---LIDTVTALWNDLGAEGCFCVEDLETGQSI-SMNEDKRMPLVSVAKLSIAAALFAEDS +AGRIDARETVLIDPATATSGSTGISLFSDPVISLRDLTVQMFSVSDNAAADAVYDRV-GS +TAIGALHNELGIRSLRVHSPMRALFGMLSLNDINSGTVRGVATMLRLIHHGEVVSPDVSA +HLRRLMRTQVF-RHRIASGFPDTAEYYGKTGTLLT-YRHDAGVVTDIDGRSYAVVVFTRS +RIYSQPELDAAIGYSARL----- +>[subseq from] Beta-lactamase n=1 Tax=Youngiibacter fragilis 232.1 TaxID=994573 RepID=V7IBA0_9CLOT +-----KEIKRYLEDRLGKYSFYFEDLKSGYIF-GYNEHVKMTSAGCMKLPVAMVVMKEIE +TGKLSLDQMVMVTEKDKVEGSGILKEFLEREYSIRELITVMLMDSDNTATQKLVSLL-GY +RNINSYIQEMGLKNTMMN--------DMPGSVINLTTSFDLSMCWKHLKNRSYINDENSQ +LLIDILKKQHK-KTKTAFYIPLKSRIASKPGDMD-GVENDTTLIELQKGD-FVFTIMSSE +LPNS-VYGLVSLAKAGKMIWD-- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. TSRI0369 TaxID=1703936 RepID=A0A1Q5H1M3_9ACTN +------ELDAHLDKVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE +TGRLDLDAPVPVRNSSALPGAPRFWDRVGGDAPLRWLAERMIVRSSNLATNICIGQV-GL +PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALAPPSACA +AMLDVLAAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT +DLADEDDACRLIAHVSERVW--- +>[subseq from] Uncharacterized protein n=2 Tax=unclassified Ruminococcus TaxID=2608920 RepID=A0A416QVC6_9FIRM +------------------------------------------------------------ +----------------------------------YSLLWDMITVSDNECYNELVRRVGGT +AVVNQYLRKNGYKNTGCHSSLHPSSSAWSSDGRNTASAKDCGMLLEKIYRGRCVSQQYSR +EMLNLLLHQTK-RYKIPSGLPAGVVCANKTGETSS-VQHDMAIIYGKKT-NYVLCIFSEG +ASED--HLLHGIRSISSRVYQ-- +>[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ297 TaxID=2572905 RepID=A0A559VDQ1_9ACTN +------DLDAHLDRVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE +AGRLDLDAPVPVRNSFDSAGVPRFWDRVGGEAPLRWLAERMIIRSSNLATNICIGQV-GL +PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAAVLGELALGRLASPAGCA +AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT +DLADSDDACRLIAHVSERV---- +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. BK141 TaxID=2512171 RepID=A0A4R7GQD8_9ACTN +---IERRLRQVFSEAGCEGSVAALDVDSENRV-MFGDTEPMVAASTFKIVVALELFCQGV +EGTLDPTERVRLSPAEATPGQGFCIFEDDAEVSLRDVARMMLTISDNTATDLLIRRV-SL +SRVHDRLGRLGLDRIRLAGTIQQEFDSLRPGRITSATTGQMAALSRLIWLDRAGPAAACR +AVRTLLGQQRL-TRKIATGFGGEVRVAAKSGTLPGCASNDVGVVEYPDGSRFAVAVFTRP +AGRRTLPPDSVLGTAARLAVE-- +>[subseq from] Uncharacterized protein n=1 Tax=Agromyces aureus TaxID=453304 RepID=A0A191WG98_9MICO +--------TQALDDAGLTASITVRDLDTGREL-SLDPDAAYPLASVVKLPLAIAVLRGAA +AGSIALADPVRIDPAERTPLTGLCRFEHPSEVAVADLLYLAICVSDDTAADALFARA-SP +TEVTALLRELGITDITVRHSIQDLHEQLDVTHANAGTSRALVDLLERLWTSPDLAPE-RE +QLRRLLGQNLM-RHRLAPDLEDDAEWFSKTGTFLH-LRHEVGVLEHADGGTFAIAVLSES +SVRRQPGAEQALGFAARLL---- +>[subseq from] Serine hydrolase n=2 Tax=Candidatus Cryosericum TaxID=2498709 RepID=A0A398DER9_9BACT +-------------------------------F-SQNSNLPFGAASIIKLPVLVCVAQLVE +LGDLVWDRPIRLTVAAP-HGTGLLEYLDRSRWSVQDLCIMMMGVSDNMACNQLIEEI-GI +ERLNDVLHDLGYEATSIRRRMMDHE-MLARGIDNSVTAADIADMLARLYAHRLVSNEASQ +RMLGYLRMNQL-KDLIAWTLPGSAALAGKTGGMP-GSLLDAELVSVADGPTYSLCVFASG +FD-RAVQAKRLMTEVSERVYE-- +>[subseq from] serine hydrolase n=1 Tax=Haloactinobacterium sp. HY164 TaxID=2675754 RepID=UPI0012B7911C +-------ASSALEDAGLRGSFLVRDLDTGREL-GLEPDLLFPLASLVKVPLALDVLELAG +TGDLDLDEQVLIDATIRVPGATGLCRFTEPAIALADLLYLAVAVSDDTAAEALFRLC-PP +EQVTRRLRSMSVTDVTVRHTIGELHRQLDVSMANSGSARAMADVFERIWSGTDLRPGTSD +RLQELLAGNLLRHRLAPDLATDAASWASKTGTFLH-LRHEVGVVTHRDGGRFVVAALTES +RVTTQPVAEQTIGWVARMLHD-- +>[subseq from] serine hydrolase n=1 Tax=Pseudonocardia spinosispora TaxID=103441 RepID=UPI00040BC58E +----AETIAADWARLGVRGHLLARHLETGDQL-GFDVHTPVPLASVAKVPIALAVLDRIA +AGDLDPGLQITIAPEGKSFPTGIAAYRYPTTVAVADLVHQMLSVSDNASADTLVDLL-GV +DGIQRSLRDWGCPGIRFRHRMHRMYETLDPEHSNVASAAALVELLERIWLDDISVPGATA +ELRRLMGLQVF-TNRLSSDLRDTVRVSGKTGTFLN-LRHEIGVVTADSGDRVAIAALTRS +TRRATHDVDLAIGAAARTAF--- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora tulbaghiae TaxID=479978 RepID=A0A386WE77_9ACTN +------ELDAHLDRVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFHATE +AGRLDLDAPVPVRNSFDSAGAPRFWDRVGGEASLRWLAERIIVRSSNLATNICIGQV-GL +PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALASPAGCA +AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT +DLADEDDACRLIAHVSERVW--- +>[subseq from] Serine hydrolase n=1 Tax=Sporolactobacillus sp. THM19-2 TaxID=2511171 RepID=A0A4Q4IHC3_9BACL +--AFTHDLSALVKPFGHHIAVEAVG-STGFHY-AHHADVPMLSASLIKLPILLYAVHRSL +SDSDFFDRKVRLPDENRVGGSGVLQILSGRDWSVRDLLALMINVSDNTATNLMLDLL-GI +GPVQTWARQHGFTDLRMERKMMDTAA-EKAGKKNMISAHDACRAIELIFPGG---QPVSE +EIGNWFLHQQF-RHKLPAELPDPVKVYNKTGEMNE-VDHDAALFTYQGHD-LYLAVLSEG +VK-DRQAVLNTIQRIG------- +>[subseq from] serine hydrolase n=1 Tax=Kocuria sp. WN036 TaxID=2032628 RepID=UPI000BAB344C +------------------------------------------------------------ +----------------------------GLGLTVEQALDVMISWSDNASGAALGQWL-GW +EQVEAFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSTV +LLMGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG +WS-DYEESAPWFGDAGR------ +>[subseq from] Surface protein PspA n=2 Tax=Faecalicoccus pleomorphus TaxID=1323 RepID=A0A380LNH4_9FIRM +------------------------------------------------------------ +-------------------------------------LEAMIIDSDNTSYNILLQKLGGA +HKVNSFCEKLGLTRTEIHHGLVPGDGYFSDGKNNTTCPEDVAKFLELLYRSDVVSKAYSK +EMLELLKRCAD-DTGIVAGLAEGTECAHKSGWAD-AYYLDGGIIYTEYKD-YILVVFSDS +SYQKP------------------ +>[subseq from] Protein kinase domain-containing protein n=1 Tax=Chloroflexi bacterium 54-19 TaxID=1895928 RepID=A0A1Q3TC15_9CHLR +-----AAISQALQSLPGATSVYIIY-PDGSFT-SDDGDRAQPSASVIKLWIAATAFQEAK +AGRLNLDENYTVQKTDIASGTGILVNNVGKTFTYEQILTTMLTYSDNSAANIVIKKLGGF +GKVNTYAQAHGYTSTKLQRLLGDISN----PNNNFTSGKDAATMMYLLSEGKVVDGNSSL +TILQALYDRRNDQNFFSPKLSADYNYLHISGTGTK-VRNEVGLVPIQNANNMIIAILDTG +VPDEGAAENAIAAAVG------- +>[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Mycolicibacterium chitae TaxID=1792 RepID=A0A3S4RH08_MYCCI +-------------------------------VvDVGGTEPVVAASVYKVIVLVALARAFD +AGQLDPRASVRVVPADCTPGPTGLSLFSDPVLSWWDLARLMITLSDNAASDVILGAL-GL +AAVEAVIEDLGLTCTRVVGGTAALQRAFDPAYTTATSGADIIAVLNGIWTGTVATPDTCS +TMRAILAQQIW-PHRIRSGFPADVMVAGKTGTIGP-IRNEAAVVEMPGETPIAVAVFTRA +ARSDLPVVDAAIGRAAHLAV--- +>[subseq from] serine hydrolase n=1 Tax=Brachybacterium timonense TaxID=2050896 RepID=UPI000D0ACE90 +-------------------------------LeSEDAARPVYAASTIKLHVLAAVLRAAD +AGRLDLTRTVPASRTFTGTGAAFTPTHPADGVSLDELAIRMIDRSSNEATDHLLEIV-GL +EAVAHEIDRLGLTATRVDRLIGDAA-AIEQGLTNESSPADLVSTLRSLMQGEGLSLRSRD +LARHALRAQRI--PIIATALRPGVPWGSKSGWVD-GYRHDVAAIGNPNGDERYLAVMTSG +MELT--AADEQIRALTRRL---- +>[subseq from] Beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=A0A328NN07_9ACTN +------DLDAHLDRVPGTVSAYVGRLAAPPTW-TRHADAGHYAASTMKVAVLAALHRAAE +AGTLDLDAPVPVVNDDSAQGAPRFWDRIGGTASLRWLADRMIVRSSNLATNLVLGHV-GL +PAVAEVWALAGARNSVTGRGIEDFAAR-EAGITNTVTAADLAALLGALATGALASPAACT +TMLDVLLAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVLPDDAPPYLIAVCTTT +DLDDEDDACLLLAHISAQVW--- +>[subseq from] Uncharacterized protein n=1 Tax=Actinobacteria bacterium 13_2_20CM_2_66_6 TaxID=1803492 RepID=A0A1Q7DKY3_9ACTN +--------------------------------------------------------ADGA +RGLLDLDERVVVG--DRVDGSGVLRHMRDLDLSLRDLAMLSIIVSDNTATNRLIERV-GL +GRVGERLREWGCSRTQLTRKMYDFEAA-KRGHENVMTPRETVSLLLRLHRGECEDRATSD +AVLAVLEQCQD-RTMLLRYLPYGTKVPHKTGTLDE-SRNDAAIV--PGDRPVIVAAFTRK +VRDT------------------- +>[subseq from] Serine hydrolase n=1 Tax=Streptomyces lavendulae TaxID=1914 RepID=A0A5C8GX07_STRLA +----EDQVRAIFERAGCMGTLLVQPLDEEREF-GLGADQLVVPASVMKVLVALAAETWFA +EGRLELRERVVLGAAGRTPGPVGLSLLADDVLSWRDMVVLMLTISDNPCTDALMNRL-GV +GTLNATAARLGLRNTVVRSDVRTLLYAPAPGAGTRTTARDMVRLLRLLWSGQAGPAEACA +RVRAVMARRLT-RHRIASGFRTPVRVAAKSGGLAGIVRNEVGVVSYPDGRRYAAAVFTRS +RTADESAINAAIGAATAHA---- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora purpureochromogenes TaxID=47872 RepID=UPI0004C2B701 +------DLDAHLDRVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE +AGRLDLDAPVAVRNSSALPGAPRFWDRVGGDAPLRWLAERMIVRSSNLATNICIGQV-GL +PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALASPSGCA +AMLDVLAAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT +DLADEDDACRLIAHVSERVW--- +>[subseq from] serine hydrolase n=1 Tax=Kocuria rhizophila TaxID=72000 RepID=UPI000DD3F311 +----EAAVEELAAGVPGELGLVVLDPDGRPVV-TRAAERSFTSASLYKLFVAHAVLERVD +RGEAALTDPV-----------------PGTALTVAQALDAMITWSDNASGAALGGQL-GW +DALEDSARAHGFTTTTFDPGTGE-----DGIVAMTTTPDDVADLLERLRRGRLLSPASTE +LFLGLLRDQHL-DYALSSGLSAGTEFAHKTGLLED-VSHDAGLLRTGGRE-HVVVVLTD- +----------------------- +>[subseq from] serine hydrolase n=1 Tax=Actinoalloteichus hymeniacidonis TaxID=340345 RepID=UPI0008528D27 +-------------------RLHALSLTTDREV-GADPDTPVVLASVVKVLIALEYARQAT +AGLLDPTSMVWVRDGDRLGGTGTAGFLDDVALSLRDLAGSMMSVSDNTAADLLLDRI-GL +AALRSAIGELGLGATTVLGAPRDILAAFDPAGTTSSTPRDMTRLLSLIWRDLAGSAAACA +EVRRLMSAQLN-WHRLAAGFDDEVLVAAKSGSLPP-IRNEIGVITYPDGRGYAVSVFVEL +TGGRRPDVDVAIGRAARLAVD-- +>[subseq from] Serine hydrolase n=1 Tax=Ruminiclostridium sp. TaxID=2053608 RepID=A0A357AJV7_9FIRM +--EIKAKAEDFISKQSGKYGVYFIDLATGEYF-GINDRDEYIAASTTKLPMNLFLYTKIE +SGEVDLESKLKYLKEDFEAGTGIIQNQPGTEYTVRETSRLSIIHSDNCGINMIIRVL-GI +ENICNYILDLG--------------GDIYYDDRHRTSPHDLGLVTQELYRLYLNNPELYG +EMIYNLENTDW-EDRISAKLPAEVKVAHKIGNQVR-TANDVGIVFAS--HPFVLAVMTKD +VD--FGTACNKIADLSKMIYDE- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora arida TaxID=2203715 RepID=A0A3N9XL88_9ACTN +------DLDAHLDRVPGTVSAYVGRLDAPPTW-TRHADAGHYAASTMKVAVLAALHRAAE +AGTLDLDAPVPVVNDDSAQGAPRFWDRIGGTASLRWLADRMIVRSSNLATNLVLGHV-GL +PAVAEVWALAGARNSVTGRGIEDFAAR-EAGITNTVTAADLAALLGTLATGALASPAACT +TMLDVLLAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVLPDDAPPYLIAVCTTT +DLDDEDDACLLLAHISAQVW--- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6RU35_9BACT +--DLVTRMNALCDALPFQTSWYLKDLATGETA-NRLGDTPVPSASTRKISIMMAALKAVH +DGKLALDQKVTIDAKYQDNDSGTFQHLTPGFISFRDALVMMIIVSDNTCTGTVVDLV-GL +GEIQRFCESIGMSRTVHRFGIPRLGPDHSLDQVTTTTPSDQGLLLEMILRGVGSTPELCR +LGLDILSWQKL-KTRLPSLLPLGTKVAHKTGTGSR-GFMDAGIVFKDDHPLFILTAYTEH +VPAALPD---------------- +>[subseq from] Beta-lactamase/transpeptidase-like protein n=1 Tax=Gonapodya prolifera (strain JEL478) TaxID=1344416 RepID=A0A139A0J8_GONPJ +----LSELAAIEPSSRGSIGVAALATAAPPAI-SFNADQRFPMASTVKVGLAATVLKLIE +RGKLALDLVVEVEDFDLCIYPEIVWGHLPAFFAVSNLLEMSLTRSDNTATDVLLKLIGGP +PTVRKYLDELGVPAMNPKSNMRDN-LAVEGDVRDSTTPAAYHTFLRLALSAHLLSPSMSA +YLLAAMSRCLS-TERIRGRLRPGVPTSVKGGSVR-GNHSEVGVVEVEGRGWITLAIYTRN +APTPMSIRERTIADVARLVYDYy +>[subseq from] Uncharacterized protein n=2 Tax=Candidatus Woykebacteria TaxID=1817899 RepID=A0A1G1WTZ2_9BACT +------------TDKQGDYAIAIKNLTTNESF-ELNQDKIFTSASLYKLWVMATAFDQIN +SGNLDLSRDIAYLNKKFFIPPDYAELTKGGILSVRSAIEQMITISHNYASLLLTDRI-KP +ESIVSFLKNYEFNGSKFGTE-AD---------PPTTTASDIALFFEKLSNGTIINRGYSD +RMLDVLKRVKR-VDKLPKYLPEAALIAHKTGELDY-FTHDGGIVYGPKG-PYIIVVLTET +KS--PPDAQETIANISKAVYNYf +>[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces atratus TaxID=1893 RepID=A0A1K1YHP9_STRAR +-----------SAALPLTLAVAAVDIDGGGTV-GVDERTVLPVASASKLLLLAEVARRLD +TGELPADRVVEVLDEDLAEGTGLLRRLSGRGWTVEDLAWLTASVSDNTATNALLRLV-GR +ESTARLAQELGLDHLTLHDKVRDVRGPDVPPVFATGTAHDLARLVTHAVRGTMSCPAASA +RLLRWMRSNTD-HGLVPALVDDGLLVANKTGTDT-GVRADAGVIIGRRRLAYAVVARWDT +ALSTERAAVHAIRDVGRTL---- +>[subseq from] Serine hydrolase n=1 Tax=Peptococcaceae bacterium TaxID=2052179 RepID=A0A419G5S2_9FIRM +--PLKKQLESYLATRKATYGIYFKDLNTGATW-GINDLTPIPAASTIKVPYVLYLNEQVA +AGRLKMEQRIAYDSNDYAGGSGYLKETAADGFTLRVLSNLAITLSDNVAYKMI-KRVTGE +ENVLAYMKAMGGTTI-------------GGNGQDNTTARDMAAYMEGVINFSRRNPALGN +RLIDDLANPIW-HYGLPGKLPDNVKVAHKEGDLP-GVSNDVGIVFAS--RPYIISILSMN +QD-NIEQGFLDISEISGMIYEY- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DC3D9DB +------DLDAHLDRVPGTVSAYVGRLAAPPTW-TRHADAGHYAASTMKVAVLAALHRAAE +AGTLDLDAPVPVVNDDSAQGAPRFWDRIGGTASLRWLADRMIVRSSNLATNLVLGHV-GL +PAVAEVWALAGARNSVTGRGIEDFAAR-EAGITNTVTAADLAALLGALATGALASPAACT +TMLDVLLAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVLPDDAPPYLIAVCTTT +ELQVEDDACLLLAHISAQVW--- +>[subseq from] Serine hydrolase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A556C507_9MICO +-----REVGDQLEAAGLRARIMVRDLDSQAEI-SVGSDVSLPLASVVKVPIALAVLSRIA +SGKLEADRQVLVEPGQFKPSSTGTSRFRHPAIAVDDLLMLSVCFSDNTATDALLQLV-PI +ELVQRELADLGFGEIQVRHHLDALVRQLDSAQANVATASVLTELLAQLWRPDRISPAVAT +RLRELMAGNVVRHRLAPDLMSDAARWSSKTGTLLH-LRHEIGVVEHADGQTIAVVVLSES +RNAVQPAAEAALGAAARALHD-- +>[subseq from] Beta-lactamase class A n=1 Tax=Nocardioides sp. YR527 TaxID=1881028 RepID=A0A1G9A7P9_9ACTN +---LAEATAERFQELRVRVAFLARDIDTGHEI-GVGGDRPMPLASVAKVPLALVVADRIA +RGEIDGGAMVTLTAAERSYPYGISAFAHDATCSVADLMLMMLGLSDNAAADALFDRV-SP +REVDEQLAEWGVEGLRVRHRMQPMYDSLDVERATVGSPRACVDLLERVWRDEVAKPEATE +LVRRLMGKQVF-THRIAALLADDIHLAGKTGGFLT-LRHEIAVVTHPGGR-VAIAVLTDS +DRTAQNDVDLAIAATARD----- +>[subseq from] hypothetical protein n=1 Tax=Bacillus rubiinfantis TaxID=1499680 RepID=UPI0009E3C7CD +--KLSTELKSYLKKTGGKVTIQYKDLSTGDVF-QINGKSSGRAASTIKLPLALYVMEQAS +KGKINLNKTLTYKSYHYFGGSGIIQKKVGTKFTIRQLVKYAMIYSDNIAFIMLKEYV-GA +SNFQKYMNSIGGQ------------YAYPRNGQTITSANDLTIYATELYQFSE-KNKYGK +ELVGYLKETVY-NTTIPRGIK-GVPIAHKVGMIPSLIYNDVAIVY--DKRPFVLAIMTQG +IA--YEKSQKVIADIAKIVYKH- +>[subseq from] Serine hydrolase n=1 Tax=Fusobacterium varium TaxID=856 RepID=A0A250LQR7_FUSVA +----EKRIKEIINENSGVAGVVIRD-SFGKLL-MINEEVVFPSASIIKLFILMALN---- +--KEDYNKRIELKKVDKVGGCGILKVMEDGLLTVKDTAYLMICLSDNTATNILIDYI-GM +DKINACIKEKGFTGTVLGRKMMDAEAR-KAGKDNFTTPKDVLGVLKMLCKNP-------- +DDLDMLRNQAY-NNKIPLYFAREVDFAHKTGELMY-IEHDAGRLFFDGG--WVDVIVLTK +DLEKNEDGIKINSLIGKVIFDNy +>[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. RV43 TaxID=1661387 RepID=UPI00064BAA12 +------DLDAHLDRVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE +AGRLDLDAPVPVRNSFDSAGVPRFWDRVGGEAPLRWLAERMIIRSSNLATNICIGQV-GL +PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAAVLGELALGALASPAGCA +AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT +DLADEDDACRLIAHVSERVW--- +>[subseq from] Beta-lactamase class A n=2 Tax=Micromonospora siamensis TaxID=299152 RepID=A0A1C5HI83_9ACTN +--------EEIYGQAGISGALHVVDVDAAREV-AVRADQQIVIASVFKILLVLEFARQAV +AGQLDPTERVLVRAADRLGGWGVAGCADDVEISLRDLAYFTMSVSDNTAADLLLRRV-GP +DVPAMLAAELGLPRTRIVGGPRQLVEVFDPERTTSSTAREITRLLGLVWRDEAGPPAACA +MVRELMGRQLF-WTRLAAAFPPGVRVAGKTGNLP-GLHLEAGVAEYPDGRRYAILVHART +ERLS------------------- +>[subseq from] serine hydrolase n=1 Tax=Micromonospora chalcea TaxID=1874 RepID=UPI000CE4AD6D +------ELDAHLDKVPGTVSAYVGRPGARPAW-TRRADATHYAASTMKLAVLVALFRAAE +AGRLDLDAPVPVRNSSALPGAPRFWDRVGGDAPLRWLAERMIVRSSNLATNICIGQV-GL +PAVARAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALASPSACA +AMLDVLAAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT +DLADEDDACRLIAHVSARVW--- +>[subseq from] Beta-lactamase class A n=2 Tax=Thermaerobacter TaxID=73918 RepID=K6P328_9FIRM +-----ARVREFIETRPQTFGIYFKDLQTGATW-GINEREPIHAASTIKVPLVLYVNHQVA +AGRARMDDRIVYEPDDLTGGAGILQRFPGKSYSLRVLTNLSITISDNVTTNMLFRHF-GK +DNVGEFMRRLGGEVIF------------PG-GRRISTARDMGIYVEAVLDFARQHPLLGG +RMLDDMGHAIF-HVGLPGELPPDVFVAHKEGDIE-GVADDVGIVF--GRRPFVLAVLSKG +VD-NIDQGFEDIARISKIVYD-- +>[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. XM-20-01 TaxID=2583240 RepID=A0A505HB76_9ACTN +------ELDAHLDKVPGTVSAYVGRPGARPAW-TRRADATHYAASTMKLAVLVALFRAAE +AGRLDLDAPVPVRNSSALPGAPRFWDRVGGDAPLRWLAERMIVRSSNLATNICIGQV-GL +PAVARAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALASPSACA +AMLDVLAAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT +DLADEDDACRLIAHVSARVW--- +>[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID685 TaxID=2690322 RepID=UPI00136914C4 +---------EIFERAGCTGTLLVQPLHGEGEF-GLDADQLVVPASVVKVLVALAAETWFA +EGRLDPRERVVLGAARRTPGTVGVSLFEDEVLSLRDMVVLMLTISDNPCTDALMNRL-GV +DTLNATAARLGLRNTVVRSDLRTMLDALTPGTGTSTTARDMVRLLRLLWSGQAGPAAACA +RVRAVMGRQLT-RHRIASGFRAPVRVAAKSGGLAGIVRNEVGVVSYPDGRQYAAAVFTRS +RPADDAAINAAIGAATAHAV--- +>[subseq from] Uncharacterized protein n=1 Tax=Kocuria sp. CNJ-770 TaxID=1904964 RepID=A0A1Q9SF54_9MICC +--TLADDLEQLALGVPGELGLVLLGPDGNELA-SRAADRPFTSASFYKLFVAHAVLERVD +RGELALDDPVP-----------------GSALTVGTALAAMISWSDNPSGAALGRWL-GW +AELEEFAHGHGFPATTFDPDTGDADRV-----AMTTTPADVAALLERLRRGELLSPASTA +LFRQLLEDQQL-DYALPSGFSPGTAFAHKTGLLED-VSHDAGLLTLDGRE-HVVVVMTD- +----------------------- +>[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium CG10_big_fil_rev_8_21_14_0_10_36_7 TaxID=1974632 RepID=A0A2M6W8D9_9BACT +------VVEKFIKEQGPKFSIYYKNLKTGASF-GVDENKILTAASLNKILIASYLYNQAD +RKKIDLEEKITIQEKDLQDGTGIRYEGAGGVYTLKTLAKLALEQSDNTAAFVLSEKL-GR +GEIEEYGKSLGLVTTNIA--------------DNKTSAKDMGILLELIFNRKIANNALTL +EFLDFMKDTDF-EDRLARDLPKSVAVYHKAADGIS-LVHDAGIIGDENF-PFILSILTNE +VR-DEEEVKKTIGQITKFIYD-- +>[subseq from] Serine hydrolase n=1 Tax=Candidatus Levybacteria bacterium TaxID=2052151 RepID=A0A4P5UKK3_9BACT +----DDVVRNSQEGTRGNYAIVIKNLKSNDIF-MQNEHLVFESASLYKLWVMGAVYKQIK +EGKIKEDDILSWDISLLNNESPSLGELSSGVLTVSDALHQMITISHNYSALMLVEKI-GI +SNLKKFIQELGLKETFVDNHS-------------RTTAYDLVIFFEKLYNGQIIDKKYSN +KMIALLKDQQI-NDRIPRFLPKSISIGHKTGEIDN-FKHDAGIVFAPKGD-YIFIVLTKS +ESP--VGAAERIATLSKEIFEFf diff --git a/esm/source/examples/variant-prediction/data/BLAT_ECOLX_Ranganathan2015.csv b/esm/source/examples/variant-prediction/data/BLAT_ECOLX_Ranganathan2015.csv new file mode 100644 index 0000000000000000000000000000000000000000..caebd0c1ffbbddf55a74e15b805a95a63d7141cb --- /dev/null +++ b/esm/source/examples/variant-prediction/data/BLAT_ECOLX_Ranganathan2015.csv @@ -0,0 +1,4997 @@ +,mutant,0,39,156,625,2500,cefotaxime,0_1,0_2,10_1,39_1,39_2,156_1,156_2,625_1,625_2,2500_1,2500_2,km,vmax,mutation_effect_prediction_vae_ensemble,mutation_effect_prediction_vae_1,mutation_effect_prediction_vae_2,mutation_effect_prediction_vae_3,mutation_effect_prediction_vae_4,mutation_effect_prediction_vae_5,mutation_effect_prediction_pairwise,mutation_effect_prediction_independent 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(replicated),0.7636633966742921,0.7615069456529638,0.012651819062077643 +135,BLAT_ECOLX_Tenaillon2013,EVMutation (replicated),0.7188975120768561,0.7181426689915423,0.015603675185522175 +136,BLAT_ECOLX_Tenaillon2013,ProtBERT-BFD,0.5849974717911389,0.5759011621581035,0.02142157252628116 +137,BLAT_ECOLX_Tenaillon2013,TAPE,0.12293837281461435,0.12415027252537572,0.02966599757403504 +138,BLAT_ECOLX_Tenaillon2013,UniRep,0.018139031023161226,0.026517625360817247,0.022618042553652993 +139,BLAT_ECOLX_Tenaillon2013,ESM-1b,0.7054857406191637,0.6998800269911201,0.021248434713645674 +294,MTH3_HAEAESTABILIZED_Tawfik2015,gt,1.0,1.0,0.0 +295,MTH3_HAEAESTABILIZED_Tawfik2015,MSA Transformer,0.6835339164997478,0.6812589032616372,0.015535718954003042 +296,MTH3_HAEAESTABILIZED_Tawfik2015,PSSM,0.4416134495623428,0.44246894551424826,0.020085764953621237 +297,MTH3_HAEAESTABILIZED_Tawfik2015,EVMutation (published),0.6941903664027441,0.692016316213505,0.013094374915061331 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(published),0.814063406437493,0.770542797914026,0.07799856588047756 +382,POL_HV1N5-CA_Ndungu2014,DeepSequence (published) - single,0.8237975570016259,0.79822473995615,0.059914597251614195 +383,POL_HV1N5-CA_Ndungu2014,DeepSequence (published),0.8152651534207193,0.7889600095175417,0.06617658502045558 +384,POL_HV1N5-CA_Ndungu2014,ESM-1v (zero shot),0.6512266902103299,0.6238138829808892,0.07766375006901825 +385,POL_HV1N5-CA_Ndungu2014,ESM-1v (+further training),0.815024804024074,0.7869525208215408,0.05466301623393627 +386,POL_HV1N5-CA_Ndungu2014,DeepSequence (replicated),0.820552840146915,0.7966023557532389,0.05723243614263114 +387,POL_HV1N5-CA_Ndungu2014,EVMutation (replicated),0.8211537136385281,0.7735182879439364,0.08095098085359952 +388,POL_HV1N5-CA_Ndungu2014,ProtBERT-BFD,0.38179501657099424,0.42193301482635154,0.14774279685397848 +389,POL_HV1N5-CA_Ndungu2014,TAPE,0.3483864504373032,0.4104118824597043,0.1470038347598428 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(replicated),0.46165721811412747,0.46807649417617975,0.022195221779086654 +373,POLG_HCVJF_Sun2014,EVMutation (replicated),0.5825890447985209,0.5852998202243922,0.022749622221884737 +374,POLG_HCVJF_Sun2014,ProtBERT-BFD,0.08677957966093554,0.07770559640019087,0.018629212118296944 +375,POLG_HCVJF_Sun2014,TAPE,0.05680250795137183,0.04875383206148289,0.02707444904306108 +376,POLG_HCVJF_Sun2014,UniRep,0.023755477003752395,0.018385016483602818,0.018204300138877978 +377,POLG_HCVJF_Sun2014,ESM-1b,0.14790101977036282,0.1451007380223277,0.018527745632610403 +308,P84126_THETH_b0,gt,1.0,1.0,0.0 +309,P84126_THETH_b0,MSA Transformer,0.5799265252107147,0.5738614544298895,0.016977861401835232 +310,P84126_THETH_b0,PSSM,0.5059938805045767,0.497875302076657,0.017450898377151254 +311,P84126_THETH_b0,EVMutation (published),0.5762676414938405,0.5713927693726344,0.015545247017306097 +312,P84126_THETH_b0,DeepSequence (published) - single,0.5267205050047176,0.5248192557448691,0.018977964279615622 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Transformer,0.48917822587769644,0.4911252194110343,0.010638436729624378 +240,HSP82_YEAST_Bolon2016,PSSM,0.5080494707835187,0.5081989816141457,0.011630856503356157 +241,HSP82_YEAST_Bolon2016,EVMutation (published),0.49012823437511943,0.4936437806547088,0.009824172602805919 +242,HSP82_YEAST_Bolon2016,DeepSequence (published) - single,0.5292966677834544,0.529631038805717,0.010670673995645957 +243,HSP82_YEAST_Bolon2016,DeepSequence (published),0.5345178740223454,0.5359585453318252,0.010405888846639616 +244,HSP82_YEAST_Bolon2016,ESM-1v (zero shot),0.5770032224447383,0.5794593692641861,0.011071932164493134 +245,HSP82_YEAST_Bolon2016,ESM-1v (+further training),0.5582427433705837,0.5611201932811588,0.011556274778765427 +246,HSP82_YEAST_Bolon2016,DeepSequence (replicated),0.5447815098744462,0.5468478860295007,0.009190852805604763 +247,HSP82_YEAST_Bolon2016,EVMutation (replicated),0.4813174874985635,0.4833921506539731,0.010641726788141665 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(published) - single,0.4429769169797119,0.4459763974635589,0.023367347171715933 +495,TIM_THEMA_b0,DeepSequence (published),0.43793312514525096,0.43932643176681746,0.02400129226573652 +496,TIM_THEMA_b0,ESM-1v (zero shot),0.5026024874119385,0.5028606317050863,0.0196194686907316 +497,TIM_THEMA_b0,ESM-1v (+further training),0.49669513157740486,0.49715001129465347,0.021252079717001313 +498,TIM_THEMA_b0,DeepSequence (replicated),0.4065555906798227,0.4088509392059708,0.02383945792859995 +499,TIM_THEMA_b0,EVMutation (replicated),0.4372508700326144,0.43818153131258974,0.022249944638541977 +500,TIM_THEMA_b0,ProtBERT-BFD,0.5030640016728883,0.505061273209954,0.02004593130312488 +501,TIM_THEMA_b0,TAPE,0.426213240694561,0.42842760017164616,0.025447870266352153 +502,TIM_THEMA_b0,UniRep,0.15476155586059467,0.14652965312897737,0.02996974334997726 +503,TIM_THEMA_b0,ESM-1b,0.45916689313021203,0.45909489666370673,0.021672817044030984 +560,YAP1_HUMAN_Fields2012-singles,gt,1.0,1.0,0.0 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(published),0.5887397586618573,0.5891289275127845,0.025473578386602996 +146,BRCA1_HUMAN_BRCT,ESM-1v (zero shot),0.43099744949022667,0.43820237951190066,0.026042969300316396 +147,BRCA1_HUMAN_BRCT,ESM-1v (+further training),0.5902839735003296,0.5924129041526023,0.022139044593609002 +148,BRCA1_HUMAN_BRCT,DeepSequence (replicated),0.6048855640279864,0.6073185827311438,0.022386535818213062 +149,BRCA1_HUMAN_BRCT,EVMutation (replicated),0.5943999321364778,0.5914745443226089,0.021113952368322746 +150,BRCA1_HUMAN_BRCT,ProtBERT-BFD,0.3807653003587669,0.38891615029062426,0.025074152619186402 +151,BRCA1_HUMAN_BRCT,TAPE,0.05185305485548559,0.06300777252497933,0.028006890598497248 +152,BRCA1_HUMAN_BRCT,UniRep,0.001009857244270908,0.024731061663019048,0.015154925933309927 +153,BRCA1_HUMAN_BRCT,ESM-1b,0.5015315617812091,0.5064634555923619,0.023953542534915467 +392,PTEN_HUMAN_Fowler2018,gt,1.0,1.0,0.0 +393,PTEN_HUMAN_Fowler2018,MSA Transformer,0.47723620402030725,0.4753707747929236,0.02041283060478458 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+362,PA_FLU_Sun2015,UniRep,0.03233737793643953,0.030453300705534824,0.023348423732335796 +363,PA_FLU_Sun2015,ESM-1b,0.0350533539652243,0.03379222480788328,0.01958723862748923 diff --git a/esm/source/examples/variant-prediction/mutation_data.bib b/esm/source/examples/variant-prediction/mutation_data.bib new file mode 100644 index 0000000000000000000000000000000000000000..3616cc930859b0a6e07b75856746b37379a0afe6 --- /dev/null +++ b/esm/source/examples/variant-prediction/mutation_data.bib @@ -0,0 +1,294 @@ +@article{wrenbeck2017deep, + title={Deep sequencing methods for protein engineering and design}, + author={Wrenbeck, Emily E and Faber, Matthew S and Whitehead, Timothy A}, + journal={Current opinion in structural biology}, + volume={45}, + pages={36--44}, + year={2017}, + publisher={Elsevier} +} +@article{klesmith2015comprehensive, + title={Comprehensive sequence-flux mapping of a levoglucosan utilization pathway in E. coli}, + author={Klesmith, Justin R and Bacik, John-Paul and Michalczyk, Ryszard and Whitehead, Timothy A}, + journal={ACS synthetic biology}, + volume={4}, + number={11}, + pages={1235--1243}, + year={2015}, + publisher={ACS Publications} +} +@article{haddox2018mapping, + title={Mapping mutational effects along the evolutionary landscape of HIV envelope}, + author={Haddox, Hugh K and Dingens, Adam S and Hilton, Sarah K and Overbaugh, Julie and Bloom, Jesse D}, + journal={Elife}, + volume={7}, + pages={e34420}, + year={2018}, + publisher={eLife Sciences Publications Limited} +} +@article{romero2015dissecting, + title={Dissecting enzyme function with microfluidic-based deep mutational scanning}, + author={Romero, Philip A and Tran, Tuan M and Abate, Adam R}, + journal={Proceedings of the National Academy of Sciences}, + volume={112}, + number={23}, + pages={7159--7164}, + year={2015}, + publisher={National Acad Sciences} +} +@article{firnberg2014comprehensive, + title={A comprehensive, high-resolution map of a gene’s fitness landscape}, + author={Firnberg, Elad and Labonte, Jason W and Gray, Jeffrey J and Ostermeier, Marc}, + journal={Molecular biology and evolution}, + volume={31}, + number={6}, + pages={1581--1592}, + year={2014}, + publisher={Oxford University Press} +} +@article{deng2012deep, + title={Deep sequencing of systematic combinatorial libraries reveals $\beta$-lactamase sequence constraints at high resolution}, + author={Deng, Zhifeng and Huang, Wanzhi and Bakkalbasi, Erol and Brown, Nicholas G and Adamski, Carolyn J and Rice, Kacie and Muzny, Donna and Gibbs, Richard A and Palzkill, Timothy}, + journal={Journal of molecular biology}, + volume={424}, + number={3-4}, + pages={150--167}, + year={2012}, + publisher={Elsevier} +} +@article{stiffler2015evolvability, + title={Evolvability as a function of purifying selection in TEM-1 $\beta$-lactamase}, + author={Stiffler, Michael A and Hekstra, Doeke R and Ranganathan, Rama}, + journal={Cell}, + volume={160}, + number={5}, + pages={882--892}, + year={2015}, + publisher={Elsevier} +} +@article{jacquier2013capturing, + title={Capturing the mutational landscape of the beta-lactamase TEM-1}, + author={Jacquier, Herv{\'e} and Birgy, Andr{\'e} and Le Nagard, Herv{\'e} and Mechulam, Yves and Schmitt, Emmanuelle and Glodt, J{\'e}r{\'e}my and Bercot, Beatrice and Petit, Emmanuelle and Poulain, Julie and Barnaud, Guil{\`e}ne and others}, + journal={Proceedings of the National Academy of Sciences}, + volume={110}, + number={32}, + pages={13067--13072}, + year={2013}, + publisher={National Acad Sciences} +} +@article{findlay2018comprehensive, + title={Comprehensive characterization of transcript diversity at the human NODAL locus}, + author={Findlay, Scott D and Postovit, Lynne-Marie}, + journal={BioRxiv}, + pages={254409}, + year={2018}, + publisher={Cold Spring Harbor Laboratory} +} +@article{mclaughlin2012spatial, + title={The spatial architecture of protein function and adaptation}, + author={McLaughlin Jr, Richard N and Poelwijk, Frank J and Raman, Arjun and Gosal, Walraj S and Ranganathan, Rama}, + journal={Nature}, + volume={491}, + number={7422}, + pages={138--142}, + year={2012}, + publisher={Nature Publishing Group} +} +@article{kitzman2015massively, + title={Massively parallel single-amino-acid mutagenesis}, + author={Kitzman, Jacob O and Starita, Lea M and Lo, Russell S and Fields, Stanley and Shendure, Jay}, + journal={Nature methods}, + volume={12}, + number={3}, + pages={203--206}, + year={2015}, + publisher={Nature Publishing Group} +} +@article{doud2016accurate, + title={Accurate measurement of the effects of all amino-acid mutations on influenza hemagglutinin}, + author={Doud, Michael B and Bloom, Jesse D}, + journal={Viruses}, + volume={8}, + number={6}, + pages={155}, + year={2016}, + publisher={Multidisciplinary Digital Publishing Institute} +} +@article{pokusaeva2019experimental, + title={An experimental assay of the interactions of amino acids from orthologous sequences shaping a complex fitness landscape}, + author={Pokusaeva, Victoria O and Usmanova, Dinara R and Putintseva, Ekaterina V and Espinar, Lorena and Sarkisyan, Karen S and Mishin, Alexander S and Bogatyreva, Natalya S and Ivankov, Dmitry N and Akopyan, Arseniy V and Avvakumov, Sergey Ya and others}, + journal={PLoS genetics}, + volume={15}, + number={4}, + pages={e1008079}, + year={2019}, + publisher={Public Library of Science San Francisco, CA USA} +} +@article{mishra2016systematic, + title={Systematic mutant analyses elucidate general and client-specific aspects of Hsp90 function}, + author={Mishra, Parul and Flynn, Julia M and Starr, Tyler N and Bolon, Daniel NA}, + journal={Cell reports}, + volume={15}, + number={3}, + pages={588--598}, + year={2016}, + publisher={Elsevier} +} +@article{kelsic2016rna, + title={RNA structural determinants of optimal codons revealed by MAGE-Seq}, + author={Kelsic, Eric D and Chung, Hattie and Cohen, Niv and Park, Jimin and Wang, Harris H and Kishony, Roy}, + journal={Cell systems}, + volume={3}, + number={6}, + pages={563--571}, + year={2016}, + publisher={Elsevier} +} +@article{melnikov2014comprehensive, + title={Comprehensive mutational scanning of a kinase in vivo reveals substrate-dependent fitness landscapes}, + author={Melnikov, Alexandre and Rogov, Peter and Wang, Li and Gnirke, Andreas and Mikkelsen, Tarjei S}, + journal={Nucleic acids research}, + volume={42}, + number={14}, + pages={e112--e112}, + year={2014}, + publisher={Oxford University Press} +} +@article{brenan2016phenotypic, + title={Phenotypic characterization of a comprehensive set of MAPK1/ERK2 missense mutants}, + author={Brenan, Lisa and Andreev, Aleksandr and Cohen, Ofir and Pantel, Sasha and Kamburov, Atanas and Cacchiarelli, Davide and Persky, Nicole S and Zhu, Cong and Bagul, Mukta and Goetz, Eva M and others}, + journal={Cell reports}, + volume={17}, + number={4}, + pages={1171--1183}, + year={2016}, + publisher={Elsevier} +} +@article{rockah2015systematic, + title={Systematic mapping of protein mutational space by prolonged drift reveals the deleterious effects of seemingly neutral mutations}, + author={Rockah-Shmuel, Liat and T{\'o}th-Petr{\'o}czy, {\'A}gnes and Tawfik, Dan S}, + journal={PLoS computational biology}, + volume={11}, + number={8}, + pages={e1004421}, + year={2015}, + publisher={Public Library of Science San Francisco, CA USA} +} +@article{wu2015functional, + title={Functional constraint profiling of a viral protein reveals discordance of evolutionary conservation and functionality}, + author={Wu, Nicholas C and Olson, C Anders and Du, Yushen and Le, Shuai and Tran, Kevin and Remenyi, Roland and Gong, Danyang and Al-Mawsawi, Laith Q and Qi, Hangfei and Wu, Ting-Ting and others}, + journal={PLoS genetics}, + volume={11}, + number={7}, + pages={e1005310}, + year={2015}, + publisher={Public Library of Science San Francisco, CA USA} +} +@article{aakre2015evolving, + title={Evolving new protein-protein interaction specificity through promiscuous intermediates}, + author={Aakre, Christopher D and Herrou, Julien and Phung, Tuyen N and Perchuk, Barrett S and Crosson, Sean and Laub, Michael T}, + journal={Cell}, + volume={163}, + number={3}, + pages={594--606}, + year={2015}, + publisher={Elsevier} +} +@article{qi2014quantitative, + title={A quantitative high-resolution genetic profile rapidly identifies sequence determinants of hepatitis C viral fitness and drug sensitivity}, + author={Qi, Hangfei and Olson, C Anders and Wu, Nicholas C and Ke, Ruian and Loverdo, Claude and Chu, Virginia and Truong, Shawna and Remenyi, Roland and Chen, Zugen and Du, Yushen and others}, + journal={PLoS pathogens}, + volume={10}, + number={4}, + pages={e1004064}, + year={2014}, + publisher={Public Library of Science San Francisco, USA} +} +@article{matreyek2018multiplex, + title={Multiplex assessment of protein variant abundance by massively parallel sequencing}, + author={Matreyek, Kenneth A and Starita, Lea M and Stephany, Jason J and Martin, Beth and Chiasson, Melissa A and Gray, Vanessa E and Kircher, Martin and Khechaduri, Arineh and Dines, Jennifer N and Hause, Ronald J and others}, + journal={Nature genetics}, + volume={50}, + number={6}, + pages={874--882}, + year={2018}, + publisher={Nature Publishing Group} +} +@article{bandaru2017deconstruction, + title={Deconstruction of the Ras switching cycle through saturation mutagenesis}, + author={Bandaru, Pradeep and Shah, Neel H and Bhattacharyya, Moitrayee and Barton, John P and Kondo, Yasushi and Cofsky, Joshua C and Gee, Christine L and Chakraborty, Arup K and Kortemme, Tanja and Ranganathan, Rama and others}, + journal={Elife}, + volume={6}, + pages={e27810}, + year={2017}, + publisher={eLife Sciences Publications Limited} +} +@article{roscoe2013analyses, + title={Analyses of the effects of all ubiquitin point mutants on yeast growth rate}, + author={Roscoe, Benjamin P and Thayer, Kelly M and Zeldovich, Konstantin B and Fushman, David and Bolon, Daniel NA}, + journal={Journal of molecular biology}, + volume={425}, + number={8}, + pages={1363--1377}, + year={2013}, + publisher={Elsevier} +} +@article{roscoe2014systematic, + title={Systematic exploration of ubiquitin sequence, E1 activation efficiency, and experimental fitness in yeast}, + author={Roscoe, Benjamin P and Bolon, Daniel NA}, + journal={Journal of molecular biology}, + volume={426}, + number={15}, + pages={2854--2870}, + year={2014}, + publisher={Elsevier} +} +@article{mavor2016determination, + title={Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting}, + author={Mavor, David and Barlow, Kyle and Thompson, Samuel and Barad, Benjamin A and Bonny, Alain R and Cario, Clinton L and Gaskins, Garrett and Liu, Zairan and Deming, Laura and Axen, Seth D and others}, + journal={Elife}, + volume={5}, + pages={e15802}, + year={2016}, + publisher={eLife Sciences Publications Limited} +} +@article{chan2017correlation, + title={Correlation of fitness landscapes from three orthologous TIM barrels originates from sequence and structure constraints}, + author={Chan, Yvonne H and Venev, Sergey V and Zeldovich, Konstantin B and Matthews, C Robert}, + journal={Nature communications}, + volume={8}, + number={1}, + pages={1--12}, + year={2017}, + publisher={Nature Publishing Group} +} +@article{melamed2013deep, + title={Deep mutational scanning of an RRM domain of the Saccharomyces cerevisiae poly (A)-binding protein}, + author={Melamed, Daniel and Young, David L and Gamble, Caitlin E and Miller, Christina R and Fields, Stanley}, + journal={Rna}, + volume={19}, + number={11}, + pages={1537--1551}, + year={2013}, + publisher={Cold Spring Harbor Lab} +} +@article{starita2013activity, + title={Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis}, + author={Starita, Lea M and Pruneda, Jonathan N and Lo, Russell S and Fowler, Douglas M and Kim, Helen J and Hiatt, Joseph B and Shendure, Jay and Brzovic, Peter S and Fields, Stanley and Klevit, Rachel E}, + journal={Proceedings of the National Academy of Sciences}, + volume={110}, + number={14}, + pages={E1263--E1272}, + year={2013}, + publisher={National Acad Sciences} +} +@article{araya2012fundamental, + title={A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function}, + author={Araya, Carlos L and Fowler, Douglas M and Chen, Wentao and Muniez, Ike and Kelly, Jeffery W and Fields, Stanley}, + journal={Proceedings of the National Academy of Sciences}, + volume={109}, + number={42}, + pages={16858--16863}, + year={2012}, + publisher={National Acad Sciences} +} diff --git a/esm/source/examples/variant-prediction/predict.py b/esm/source/examples/variant-prediction/predict.py new file mode 100644 index 0000000000000000000000000000000000000000..81d72c406ad8d3016ba48c7b945d55af87ea8c93 --- /dev/null +++ b/esm/source/examples/variant-prediction/predict.py @@ -0,0 +1,241 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import argparse +import pathlib +import string + +import torch + +from esm import Alphabet, FastaBatchedDataset, ProteinBertModel, pretrained, MSATransformer +import pandas as pd +from tqdm import tqdm +from Bio import SeqIO +import itertools +from typing import List, Tuple +import numpy as np + + +def remove_insertions(sequence: str) -> str: + """ Removes any insertions into the sequence. Needed to load aligned sequences in an MSA. """ + # This is an efficient way to delete lowercase characters and insertion characters from a string + deletekeys = dict.fromkeys(string.ascii_lowercase) + deletekeys["."] = None + deletekeys["*"] = None + + translation = str.maketrans(deletekeys) + return sequence.translate(translation) + + +def read_msa(filename: str, nseq: int) -> List[Tuple[str, str]]: + """ Reads the first nseq sequences from an MSA file, automatically removes insertions. + + The input file must be in a3m format (although we use the SeqIO fasta parser) + for remove_insertions to work properly.""" + + msa = [ + (record.description, remove_insertions(str(record.seq))) + for record in itertools.islice(SeqIO.parse(filename, "fasta"), nseq) + ] + return msa + + +def create_parser(): + parser = argparse.ArgumentParser( + description="Label a deep mutational scan with predictions from an ensemble of ESM-1v models." # noqa + ) + + # fmt: off + parser.add_argument( + "--model-location", + type=str, + help="PyTorch model file OR name of pretrained model to download (see README for models)", + nargs="+", + ) + parser.add_argument( + "--sequence", + type=str, + help="Base sequence to which mutations were applied", + ) + parser.add_argument( + "--dms-input", + type=pathlib.Path, + help="CSV file containing the deep mutational scan", + ) + parser.add_argument( + "--mutation-col", + type=str, + default="mutant", + help="column in the deep mutational scan labeling the mutation as 'AiB'" + ) + parser.add_argument( + "--dms-output", + type=pathlib.Path, + help="Output file containing the deep mutational scan along with predictions", + ) + parser.add_argument( + "--offset-idx", + type=int, + default=0, + help="Offset of the mutation positions in `--mutation-col`" + ) + parser.add_argument( + "--scoring-strategy", + type=str, + default="wt-marginals", + choices=["wt-marginals", "pseudo-ppl", "masked-marginals"], + help="" + ) + parser.add_argument( + "--msa-path", + type=pathlib.Path, + help="path to MSA in a3m format (required for MSA Transformer)" + ) + parser.add_argument( + "--msa-samples", + type=int, + default=400, + help="number of sequences to select from the start of the MSA" + ) + # fmt: on + parser.add_argument("--nogpu", action="store_true", help="Do not use GPU even if available") + return parser + + +def label_row(row, sequence, token_probs, alphabet, offset_idx): + wt, idx, mt = row[0], int(row[1:-1]) - offset_idx, row[-1] + assert sequence[idx] == wt, "The listed wildtype does not match the provided sequence" + + wt_encoded, mt_encoded = alphabet.get_idx(wt), alphabet.get_idx(mt) + + # add 1 for BOS + score = token_probs[0, 1 + idx, mt_encoded] - token_probs[0, 1 + idx, wt_encoded] + return score.item() + + +def compute_pppl(row, sequence, model, alphabet, offset_idx): + wt, idx, mt = row[0], int(row[1:-1]) - offset_idx, row[-1] + assert sequence[idx] == wt, "The listed wildtype does not match the provided sequence" + + # modify the sequence + sequence = sequence[:idx] + mt + sequence[(idx + 1) :] + + # encode the sequence + data = [ + ("protein1", sequence), + ] + + batch_converter = alphabet.get_batch_converter() + + batch_labels, batch_strs, batch_tokens = batch_converter(data) + + wt_encoded, mt_encoded = alphabet.get_idx(wt), alphabet.get_idx(mt) + + # compute probabilities at each position + log_probs = [] + for i in range(1, len(sequence) - 1): + batch_tokens_masked = batch_tokens.clone() + batch_tokens_masked[0, i] = alphabet.mask_idx + with torch.no_grad(): + token_probs = torch.log_softmax(model(batch_tokens_masked.cuda())["logits"], dim=-1) + log_probs.append(token_probs[0, i, alphabet.get_idx(sequence[i])].item()) # vocab size + return sum(log_probs) + + +def main(args): + # Load the deep mutational scan + df = pd.read_csv(args.dms_input) + + # inference for each model + for model_location in args.model_location: + model, alphabet = pretrained.load_model_and_alphabet(model_location) + model.eval() + if torch.cuda.is_available() and not args.nogpu: + model = model.cuda() + print("Transferred model to GPU") + + batch_converter = alphabet.get_batch_converter() + + if isinstance(model, MSATransformer): + data = [read_msa(args.msa_path, args.msa_samples)] + assert ( + args.scoring_strategy == "masked-marginals" + ), "MSA Transformer only supports masked marginal strategy" + + batch_labels, batch_strs, batch_tokens = batch_converter(data) + + all_token_probs = [] + for i in tqdm(range(batch_tokens.size(2))): + batch_tokens_masked = batch_tokens.clone() + batch_tokens_masked[0, 0, i] = alphabet.mask_idx # mask out first sequence + with torch.no_grad(): + token_probs = torch.log_softmax( + model(batch_tokens_masked.cuda())["logits"], dim=-1 + ) + all_token_probs.append(token_probs[:, 0, i]) # vocab size + token_probs = torch.cat(all_token_probs, dim=0).unsqueeze(0) + df[model_location] = df.apply( + lambda row: label_row( + row[args.mutation_col], args.sequence, token_probs, alphabet, args.offset_idx + ), + axis=1, + ) + + else: + data = [ + ("protein1", args.sequence), + ] + batch_labels, batch_strs, batch_tokens = batch_converter(data) + + if args.scoring_strategy == "wt-marginals": + with torch.no_grad(): + token_probs = torch.log_softmax(model(batch_tokens.cuda())["logits"], dim=-1) + df[model_location] = df.apply( + lambda row: label_row( + row[args.mutation_col], + args.sequence, + token_probs, + alphabet, + args.offset_idx, + ), + axis=1, + ) + elif args.scoring_strategy == "masked-marginals": + all_token_probs = [] + for i in tqdm(range(batch_tokens.size(1))): + batch_tokens_masked = batch_tokens.clone() + batch_tokens_masked[0, i] = alphabet.mask_idx + with torch.no_grad(): + token_probs = torch.log_softmax( + model(batch_tokens_masked.cuda())["logits"], dim=-1 + ) + all_token_probs.append(token_probs[:, i]) # vocab size + token_probs = torch.cat(all_token_probs, dim=0).unsqueeze(0) + df[model_location] = df.apply( + lambda row: label_row( + row[args.mutation_col], + args.sequence, + token_probs, + alphabet, + args.offset_idx, + ), + axis=1, + ) + elif args.scoring_strategy == "pseudo-ppl": + tqdm.pandas() + df[model_location] = df.progress_apply( + lambda row: compute_pppl( + row[args.mutation_col], args.sequence, model, alphabet, args.offset_idx + ), + axis=1, + ) + + df.to_csv(args.dms_output) + + +if __name__ == "__main__": + parser = create_parser() + args = parser.parse_args() + main(args) diff --git a/esm/source/hubconf.py b/esm/source/hubconf.py new file mode 100644 index 0000000000000000000000000000000000000000..b1253ef1efa3374d6083e8aeffab64cf148c1370 --- /dev/null +++ b/esm/source/hubconf.py @@ -0,0 +1,43 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +dependencies = ["torch"] + +from esm.pretrained import ( + esm1_t6_43M_UR50S, + esm1_t12_85M_UR50S, + esm1_t34_670M_UR50D, + esm1_t34_670M_UR50S, + esm1_t34_670M_UR100, + esm1b_t33_650M_UR50S, + esm1v_t33_650M_UR90S, + esm1v_t33_650M_UR90S_1, + esm1v_t33_650M_UR90S_2, + esm1v_t33_650M_UR90S_3, + esm1v_t33_650M_UR90S_4, + esm1v_t33_650M_UR90S_5, + esm2_t6_8M_UR50D, + esm2_t12_35M_UR50D, + esm2_t30_150M_UR50D, + esm2_t33_650M_UR50D, + esm2_t36_3B_UR50D, + esm2_t48_15B_UR50D, + esm_if1_gvp4_t16_142M_UR50, + esm_msa1_t12_100M_UR50S, + esm_msa1b_t12_100M_UR50S, + esmfold_structure_module_only_8M, + esmfold_structure_module_only_8M_270K, + esmfold_structure_module_only_35M, + esmfold_structure_module_only_35M_270K, + esmfold_structure_module_only_150M, + esmfold_structure_module_only_150M_270K, + esmfold_structure_module_only_650M, + esmfold_structure_module_only_650M_270K, + esmfold_structure_module_only_3B, + esmfold_structure_module_only_3B_270K, + esmfold_structure_module_only_15B, + esmfold_v0, + esmfold_v1, +) diff --git a/esm/source/pyproject.toml b/esm/source/pyproject.toml new file mode 100644 index 0000000000000000000000000000000000000000..95693a424164819a706bc0964a2ff240d49d4a10 --- /dev/null +++ b/esm/source/pyproject.toml @@ -0,0 +1,12 @@ +[tool.black] +line-length = 99 +exclude = ''' +/( + \.git + | __pycache__ + | build + | dist + | experimental + | third_party +)/ +''' diff --git a/esm/source/scripts/__init__.py b/esm/source/scripts/__init__.py new file mode 100644 index 0000000000000000000000000000000000000000..8b137891791fe96927ad78e64b0aad7bded08bdc --- /dev/null +++ b/esm/source/scripts/__init__.py @@ -0,0 +1 @@ + diff --git a/esm/source/scripts/atlas/README.md b/esm/source/scripts/atlas/README.md new file mode 100644 index 0000000000000000000000000000000000000000..715a25dbf9ea0ce984d150208d302b64df8e5f06 --- /dev/null +++ b/esm/source/scripts/atlas/README.md @@ -0,0 +1,100 @@ +# ESM Metagenomic Atlas + +The [ESM Metagenomic Atlas](https://esmatlas.com) is a resource of more than 700 million metagenomic protein structures predicted by ESMFold. +See our [blog post](https://ai.facebook.com/blog/protein-folding-esmfold-metagenomics/) to learn more. + +The first `v0` version of the Atlas was released on November 1st 2022, +corresponding to the sequences in the `2022_05` release of the MGnify protein database described [here](https://ftp.ebi.ac.uk/pub/databases/metagenomics/peptide_database/2022_05/README.txt). +An update `v2023_02` was released on March 17th 2023, corresponding to the sequences in the `2023_02` release of the MGnify protein database described [here](https://ftp.ebi.ac.uk/pub/databases/metagenomics/peptide_database/2023_02/). + +Here we provide bulk download instructions for the tarballs of predicted structures, as well as foldseek databases, and LM embeddings for every sequence in the Atlas. + +The structures in the ESM Metagenomic Atlas were predicted with `esm.pretrained.esmfold_v0()` for Atlas `v0`, while Atlas `v2023_02` used `esm.pretrained.esmfold_v1()`. +We find that protein structures with predicted LDDT > 0.7 and predict TM > 0.7 to be both reasonably well structured and interesting. +Therefore, we provide both the small set of "high confidence" metagenomic structures from Atlas `v0`, as well as the full set. +The small set of structures is built from taking a 30% sequence identity clustering of MGnify90 `2022_05`, and using the best structure from each cluster. +The best structure is selected using the score pTM * pLDDT. + +The high confidence structures are around 1TB in size. + +The full database is available as PDB structures and is 15TB in size for `v0`. + +As an entrypoint into the database, the metadata is available as a small (~25 GB) file [metadata.sqlite](https://dl.fbaipublicfiles.com/esmatlas/v2023_02/metadata-rc2.sqlite.gz) / [metadata.parquet](https://dl.fbaipublicfiles.com/esmatlas/v2023_02/metadata-rc2.parquet). +You can load the file with pandas: `df = pd.read_parquet('metadata.parquet')`. +The dataframe has 773,846,840 records, and the file size is around 16GB. +This dataframe has 10 columns: +- `id` is the MGnify ID +- `ptm` is the predicted TM score +- `plddt` is the predicted average lddt +- `num_conf` is the number of residues with plddt > 0.7 +- `len` is the total residues in the protein +- `is_fragment` indicates whether the protein sequence is identified as a fragment in the MGnify90 sequence database. +- `sequenceChecksum` is the CRC64 hash of the sequence. Can be used for cheaper lookups. +- `esmfold_version` is the version of ESMFold, matching the model accessible as `esm.pretrained.esmfold_v{0,1}` +- `atlas_version` is the Atlas version where this structure first appeared. Note: some of the predictions appearing for the first time in `v0` are also part of Atlas `v2023_02`. +- `sequence_dbs` is the metagenomic source databases where this structure is part of, as `MGnify90_2022_05`, comma-separated if it exists in more than one release, as `MGnify90_2022_05,MGnify90_2023_02`. + +Proteins longer than 1280 residues were not folded. To select only the records without missing structures use `df[~df.plddt.isna()]`. + +We recommend using `s5cmd` or `aria2c` to download files (can be installed via conda package manager). +To download any of the structures provided, you can use this `aria2c` command: +``` +aria2c --dir=/path/to/download/to --input-file=url-file-provided.txt +``` + + +# Full database + +We separate the database by pTM and pLDDT. +This will allow you to download structures based on your needs - for example you can choose to download only the most high confidence structures. +Structures are provided by the bins given in this repo under [v0/full/bins.txt](v0/full/bins.txt) and [v2023_02/full/bins.txt](v2023_02/full/bins.txt). +For example, the foldseek database containing ptm from 0.60 to 0.70 and plddt from 0.80 to 0.90 is named `tm_.60_.70_plddt_.80_.90.DB`. +The data are given as bundles of 500k or 1M structures each. + +* **Bulk Predicted structures**: see `{v0,v2023_02}/full/tarballs/`. The URLs for all shards of a single bundle will be in e.g. [v0/full/tarballs/tm_.60_.70_plddt_.80_.90.txt](v0/full/tarballs/tm_.60_.70_plddt_.80_.90.txt). The URLs for all tarballs across bins and their shards is available under `{v0,v2023_02}/full/tarballs.txt`. +* **Foldseek DBs** `{v0,v2023_02}/full/foldseekdb/` and `{v0,v2023_02}/full/foldseekdb.txt` +* **Bulk Embeddings (NEW)** under `{v0,v2023_02}/full/esm2_embeddings/` and `{v0,v2023_02}/full/esm2_embeddings.txt`. + * Note: Individual LM embeddings can be fetched via the API endpoint `/fetchEmbedding/ESM2/:id` as described on + + +# High confidence MGnify30 structures + +The high confidence MGnify30 structures are built using this procedure: +1. MGnify90 is clustered down to 30% sequence similarity with `mmseqs easy-linclust --kmer-per-seq 100 -cluster-mode 2 --cov-mode 1 -c 0.8`. +1. Structures are filtered to >0.7 pTM and pLDDT +1. Structures are sorted by `pTM * pLDDT` and the best from each cluster is chosen as the representative. + + +We provide the urls to v0 in [v0/highquality_clust30/tarballs.txt](v0/highquality_clust30/tarballs.txt) and [v0/highquality_clust30/foldseekdb.txt](v0/highquality_clust30/foldseekdb.txt). + +As a reminder, please use `aria2c --dir=/path/to/download/to --input-file=v0/highquality_clust30/foldseekdb.txt` to download the foldseek database + +The sequences corresponding to the high confidence structures can be downloaded from . + +# Citation +If you use any of the ESM Metagenomic Atlas data in your work, please cite + + +```bibtex +@article{lin2022evolutionary, + title={Evolutionary-scale prediction of atomic level protein structure with a language model}, + author={Lin, Zeming and Akin, Halil and Rao, Roshan and Hie, Brian and Zhu, Zhongkai and Lu, Wenting and Smetanin, Nikita and Verkuil, Robert and Kabeli, Ori and Shmueli, Yaniv and dos Santos Costa, Allan and Fazel-Zarandi, Maryam and Sercu, Tom and Candido, Salvatore and Rives, Alexander}, + year={2022}, + journal={bioRxiv}, + note={bioRxiv 2022.07.20.500902}, + url={https://doi.org/10.1101/2022.07.20.500902}, +} +``` + +## License + +ESM Metagenomic Atlas (also referred to as “ESM Metagenomic Structure Atlas” or “ESM Atlas”) data is available under a CC BY 4.0 license for academic and commercial use. Copyright (c) Meta Platforms, Inc. All Rights Reserved. Use of the ESM Metagenomic Atlas data is subject to the Meta Open Source [Terms of Use](https://opensource.fb.com/legal/terms/) and [Privacy Policy](https://opensource.fb.com/legal/privacy/). + +If you make use of a structure predicted by ESMFold, please cite the following paper: + +``` +Zeming Lin, Halil Akin, Roshan Rao, Brian Hie, Zhongkai Zhu, Wenting Lu, Nikita Smetanin, Robert Verkuil, Ori Kabeli, Yaniv Shmueli, Allan dos Santos Costa, Maryam Fazel-Zarandi, Tom Sercu, Sal Candido, Alexander Rives. +Evolutionary-scale prediction of atomic level protein structure with a language model. +Science 379, 6637 (2023). +https://www.science.org/doi/abs/10.1126/science.ade2574 +``` diff --git a/esm/source/scripts/atlas/v0/full/bins.txt b/esm/source/scripts/atlas/v0/full/bins.txt new file mode 100644 index 0000000000000000000000000000000000000000..54ab0908a6ae6a5f031c4594d3aaffdd15e40e4f --- /dev/null +++ b/esm/source/scripts/atlas/v0/full/bins.txt @@ -0,0 +1,72 @@ +tm_.40_.50_plddt_.40_.50 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+https://dl.fbaipublicfiles.com/esmatlas/v2023_02/full/tarballs/tm_0_.40_plddt_0_.40_28.tar.gz diff --git a/esm/source/scripts/download_weights.sh b/esm/source/scripts/download_weights.sh new file mode 100644 index 0000000000000000000000000000000000000000..c95247ceaca7db52af476625d58b4e74d558b8de --- /dev/null +++ b/esm/source/scripts/download_weights.sh @@ -0,0 +1,65 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +#! /bin/sh +# Usage: bash /esm/scripts/download_weights.sh /path/to/weights/ +# re run the command to continue downloading incomplete files. +echo $0 +run_dir=$(readlink -f $(dirname $0)) ; + +if [[ "$(which aria2c)" == "" ]];then + echo aria2c is required for downloading! + exit 1 +fi + +for _sh_exec in /bin/sh bash zsh;do + # only bash and zsh are tested. + _sh_exec=$(which ${_sh_exec}) + if [[ "$(${_sh_exec} --version)" =~ "bash" || "$(${_sh_exec} --version)" =~ "zsh" ]];then + echo $(which ${_sh_exec}); + break + fi +done + +model_pth=$1 +if [[ "$model_pth" == "" ]];then + model_pth=$PWD +fi + +mkdir -p $model_pth/checkpoints + +pushd $model_pth/checkpoints +cat $run_dir/../README.md |grep -e '^|' |grep -e 'fair-esm/models' |tr -d '|' | \ + awk 'BEGIN{print "set -e"}; + { + # read urls starts with https + split($0,arr,"https"); + url="https"arr[2]; + + # remove blank spaces after url string + split(url,url_arr," ") + url=url_arr[1] + + # guessing regression pt url + url_regression=url; + sub("models","regression",url_regression); + sub(".pt","-contact-regression.pt",url_regression); + + # downloading weight + url_basename_idx=split(url,url_arr,"/") + url_basename=url_arr[url_basename_idx] + print "if [[ ! -f "url_basename" || -f "url_basename".aria2 ]];then echo Download not complete: "url_basename";aria2c -x 10 "url";else echo Download complete: "url_basename";fi" + + # downloading regression, if not existing and through an error, we just ignore it. + url_regression_basename_idx=split(url_regression,url_arr,"/") + url_regression_basename=url_arr[url_regression_basename_idx] + print "if [[ ! -f "url_regression_basename" || -f "url_regression_basename".aria2 ]];then echo Download not complete: "url_regression_basename";aria2c -x 10 "url_regression" 2>/dev/null || echo Never mind. "url_regression_basename" may not exist. ;else echo Download complete: "url_regression_basename";fi" + + }' |$_sh_exec + + +echo "Your model directory is located at \`$(readlink -f ${model_pth})\`." + +popd \ No newline at end of file diff --git a/esm/source/scripts/extract.py b/esm/source/scripts/extract.py new file mode 100644 index 0000000000000000000000000000000000000000..9e5bcb35a9d91e792b01a0c8f80e4f81885e1f20 --- /dev/null +++ b/esm/source/scripts/extract.py @@ -0,0 +1,140 @@ +#!/usr/bin/env python3 -u +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import argparse +import pathlib + +import torch + +from esm import Alphabet, FastaBatchedDataset, ProteinBertModel, pretrained, MSATransformer + + +def create_parser(): + parser = argparse.ArgumentParser( + description="Extract per-token representations and model outputs for sequences in a FASTA file" # noqa + ) + + parser.add_argument( + "model_location", + type=str, + help="PyTorch model file OR name of pretrained model to download (see README for models)", + ) + parser.add_argument( + "fasta_file", + type=pathlib.Path, + help="FASTA file on which to extract representations", + ) + parser.add_argument( + "output_dir", + type=pathlib.Path, + help="output directory for extracted representations", + ) + + parser.add_argument("--toks_per_batch", type=int, default=4096, help="maximum batch size") + parser.add_argument( + "--repr_layers", + type=int, + default=[-1], + nargs="+", + help="layers indices from which to extract representations (0 to num_layers, inclusive)", + ) + parser.add_argument( + "--include", + type=str, + nargs="+", + choices=["mean", "per_tok", "bos", "contacts"], + help="specify which representations to return", + required=True, + ) + parser.add_argument( + "--truncation_seq_length", + type=int, + default=1022, + help="truncate sequences longer than the given value", + ) + + parser.add_argument("--nogpu", action="store_true", help="Do not use GPU even if available") + return parser + + +def run(args): + model, alphabet = pretrained.load_model_and_alphabet(args.model_location) + model.eval() + if isinstance(model, MSATransformer): + raise ValueError( + "This script currently does not handle models with MSA input (MSA Transformer)." + ) + if torch.cuda.is_available() and not args.nogpu: + model = model.cuda() + print("Transferred model to GPU") + + dataset = FastaBatchedDataset.from_file(args.fasta_file) + batches = dataset.get_batch_indices(args.toks_per_batch, extra_toks_per_seq=1) + data_loader = torch.utils.data.DataLoader( + dataset, collate_fn=alphabet.get_batch_converter(args.truncation_seq_length), batch_sampler=batches + ) + print(f"Read {args.fasta_file} with {len(dataset)} sequences") + + args.output_dir.mkdir(parents=True, exist_ok=True) + return_contacts = "contacts" in args.include + + assert all(-(model.num_layers + 1) <= i <= model.num_layers for i in args.repr_layers) + repr_layers = [(i + model.num_layers + 1) % (model.num_layers + 1) for i in args.repr_layers] + + with torch.no_grad(): + for batch_idx, (labels, strs, toks) in enumerate(data_loader): + print( + f"Processing {batch_idx + 1} of {len(batches)} batches ({toks.size(0)} sequences)" + ) + if torch.cuda.is_available() and not args.nogpu: + toks = toks.to(device="cuda", non_blocking=True) + + out = model(toks, repr_layers=repr_layers, return_contacts=return_contacts) + + logits = out["logits"].to(device="cpu") + representations = { + layer: t.to(device="cpu") for layer, t in out["representations"].items() + } + if return_contacts: + contacts = out["contacts"].to(device="cpu") + + for i, label in enumerate(labels): + args.output_file = args.output_dir / f"{label}.pt" + args.output_file.parent.mkdir(parents=True, exist_ok=True) + result = {"label": label} + truncate_len = min(args.truncation_seq_length, len(strs[i])) + # Call clone on tensors to ensure tensors are not views into a larger representation + # See https://github.com/pytorch/pytorch/issues/1995 + if "per_tok" in args.include: + result["representations"] = { + layer: t[i, 1 : truncate_len + 1].clone() + for layer, t in representations.items() + } + if "mean" in args.include: + result["mean_representations"] = { + layer: t[i, 1 : truncate_len + 1].mean(0).clone() + for layer, t in representations.items() + } + if "bos" in args.include: + result["bos_representations"] = { + layer: t[i, 0].clone() for layer, t in representations.items() + } + if return_contacts: + result["contacts"] = contacts[i, : truncate_len, : truncate_len].clone() + + torch.save( + result, + args.output_file, + ) + + +def main(): + parser = create_parser() + args = parser.parse_args() + run(args) + +if __name__ == "__main__": + main() diff --git a/esm/source/scripts/fold.py b/esm/source/scripts/fold.py new file mode 100644 index 0000000000000000000000000000000000000000..482cdc911b2b68c6fc773b7935611764ecd1aa63 --- /dev/null +++ b/esm/source/scripts/fold.py @@ -0,0 +1,205 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. + +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + + +from pathlib import Path +import sys,os +import argparse +import logging +import sys +import typing as T +from pathlib import Path +from timeit import default_timer as timer + +import torch + +import esm +from esm.data import read_fasta + +logger = logging.getLogger() +logger.setLevel(logging.INFO) + +formatter = logging.Formatter( + "%(asctime)s | %(levelname)s | %(name)s | %(message)s", + datefmt="%y/%m/%d %H:%M:%S", +) + +console_handler = logging.StreamHandler(sys.stdout) +console_handler.setLevel(logging.INFO) +console_handler.setFormatter(formatter) +logger.addHandler(console_handler) + + +PathLike = T.Union[str, Path] + + +def enable_cpu_offloading(model): + from torch.distributed.fsdp import CPUOffload, FullyShardedDataParallel + from torch.distributed.fsdp.wrap import enable_wrap, wrap + + torch.distributed.init_process_group( + backend="nccl", init_method="tcp://localhost:9999", world_size=1, rank=0 + ) + + wrapper_kwargs = dict(cpu_offload=CPUOffload(offload_params=True)) + + with enable_wrap(wrapper_cls=FullyShardedDataParallel, **wrapper_kwargs): + for layer_name, layer in model.layers.named_children(): + wrapped_layer = wrap(layer) + setattr(model.layers, layer_name, wrapped_layer) + model = wrap(model) + + return model + + +def init_model_on_gpu_with_cpu_offloading(model): + model = model.eval() + model_esm = enable_cpu_offloading(model.esm) + del model.esm + model.cuda() + model.esm = model_esm + return model + + +def create_batched_sequence_datasest( + sequences: T.List[T.Tuple[str, str]], max_tokens_per_batch: int = 1024 +) -> T.Generator[T.Tuple[T.List[str], T.List[str]], None, None]: + + batch_headers, batch_sequences, num_tokens = [], [], 0 + for header, seq in sequences: + if (len(seq) + num_tokens > max_tokens_per_batch) and num_tokens > 0: + yield batch_headers, batch_sequences + batch_headers, batch_sequences, num_tokens = [], [], 0 + batch_headers.append(header) + batch_sequences.append(seq) + num_tokens += len(seq) + + yield batch_headers, batch_sequences + + +def create_parser(): + parser = argparse.ArgumentParser() + parser.add_argument( + "-i", + "--fasta", + help="Path to input FASTA file", + type=Path, + required=True, + ) + parser.add_argument( + "-o", "--pdb", help="Path to output PDB directory", type=Path, required=True + ) + parser.add_argument( + "-m", "--model-dir", help="Parent path to Pretrained ESM data directory. ", type=Path, default=None + ) + parser.add_argument( + "--num-recycles", + type=int, + default=None, + help="Number of recycles to run. Defaults to number used in training (4).", + ) + parser.add_argument( + "--max-tokens-per-batch", + type=int, + default=1024, + help="Maximum number of tokens per gpu forward-pass. This will group shorter sequences together " + "for batched prediction. Lowering this can help with out of memory issues, if these occur on " + "short sequences.", + ) + parser.add_argument( + "--chunk-size", + type=int, + default=None, + help="Chunks axial attention computation to reduce memory usage from O(L^2) to O(L). " + "Equivalent to running a for loop over chunks of of each dimension. Lower values will " + "result in lower memory usage at the cost of speed. Recommended values: 128, 64, 32. " + "Default: None.", + ) + parser.add_argument("--cpu-only", help="CPU only", action="store_true") + parser.add_argument("--cpu-offload", help="Enable CPU offloading", action="store_true") + return parser + + +def run(args): + if not args.fasta.exists(): + raise FileNotFoundError(args.fasta) + + args.pdb.mkdir(exist_ok=True) + + # Read fasta and sort sequences by length + logger.info(f"Reading sequences from {args.fasta}") + all_sequences = sorted(read_fasta(args.fasta), key=lambda header_seq: len(header_seq[1])) + logger.info(f"Loaded {len(all_sequences)} sequences from {args.fasta}") + + logger.info("Loading model") + + # Use pre-downloaded ESM weights from model_pth. + if args.model_dir is not None: + # if pretrained model path is available + torch.hub.set_dir(args.model_dir) + + model = esm.pretrained.esmfold_v1() + + + model = model.eval() + model.set_chunk_size(args.chunk_size) + + if args.cpu_only: + model.esm.float() # convert to fp32 as ESM-2 in fp16 is not supported on CPU + model.cpu() + elif args.cpu_offload: + model = init_model_on_gpu_with_cpu_offloading(model) + else: + model.cuda() + logger.info("Starting Predictions") + batched_sequences = create_batched_sequence_datasest(all_sequences, args.max_tokens_per_batch) + + num_completed = 0 + num_sequences = len(all_sequences) + for headers, sequences in batched_sequences: + start = timer() + try: + output = model.infer(sequences, num_recycles=args.num_recycles) + except RuntimeError as e: + if e.args[0].startswith("CUDA out of memory"): + if len(sequences) > 1: + logger.info( + f"Failed (CUDA out of memory) to predict batch of size {len(sequences)}. " + "Try lowering `--max-tokens-per-batch`." + ) + else: + logger.info( + f"Failed (CUDA out of memory) on sequence {headers[0]} of length {len(sequences[0])}." + ) + + continue + raise + + output = {key: value.cpu() for key, value in output.items()} + pdbs = model.output_to_pdb(output) + tottime = timer() - start + time_string = f"{tottime / len(headers):0.1f}s" + if len(sequences) > 1: + time_string = time_string + f" (amortized, batch size {len(sequences)})" + for header, seq, pdb_string, mean_plddt, ptm in zip( + headers, sequences, pdbs, output["mean_plddt"], output["ptm"] + ): + output_file = args.pdb / f"{header}.pdb" + output_file.write_text(pdb_string) + num_completed += 1 + logger.info( + f"Predicted structure for {header} with length {len(seq)}, pLDDT {mean_plddt:0.1f}, " + f"pTM {ptm:0.3f} in {time_string}. " + f"{num_completed} / {num_sequences} completed." + ) + + +def main(): + parser = create_parser() + args = parser.parse_args() + run(args) + +if __name__ == "__main__": + main() diff --git a/esm/source/setup.py b/esm/source/setup.py new file mode 100644 index 0000000000000000000000000000000000000000..1c8fcf4edf4a9cb6e597bb07983d3421d0156ed6 --- /dev/null +++ b/esm/source/setup.py @@ -0,0 +1,56 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +from setuptools import setup + + +with open("esm/version.py") as infile: + exec(infile.read()) + +with open("README.md") as f: + readme = f.read() + +extras = { + "esmfold": [ # OpenFold does not automatically pip install requirements, so we add them here. + "biopython", + "deepspeed==0.5.9", + "dm-tree", + "pytorch-lightning", + "omegaconf", + "ml-collections", + "einops", + "scipy", + ] +} + +sources = { + "esm": "esm", + "esm.model": "esm/model", + "esm.inverse_folding": "esm/inverse_folding", + "esm.esmfold.v1": "esm/esmfold/v1", + "esm.scripts": "scripts" +} + +setup( + name="fair-esm", + version=version, + description="Evolutionary Scale Modeling (esm): Pretrained language models for proteins. From Facebook AI Research.", + long_description=readme, + long_description_content_type="text/markdown", + author="Facebook AI Research", + url="https://github.com/facebookresearch/esm", + license="MIT", + packages=sources.keys(), + package_dir=sources, + extras_require=extras, + data_files=[("source_docs/esm", ["LICENSE", "README.md", "CODE_OF_CONDUCT.rst"])], + zip_safe=True, + entry_points={ + "console_scripts": [ + "esm-extract=esm.scripts.extract:main", + "esm-fold=esm.scripts.fold:main", + ] + }, +) diff --git a/esm/source/tests/inverse_folding_test_example.json b/esm/source/tests/inverse_folding_test_example.json new file mode 100644 index 0000000000000000000000000000000000000000..c1135d41e439af462daa76425d45c3a94de3894a --- /dev/null +++ b/esm/source/tests/inverse_folding_test_example.json @@ -0,0 +1 @@ +[{"coords": [[[Infinity, Infinity, Infinity], [Infinity, Infinity, Infinity], [Infinity, Infinity, Infinity]], [[99.86399841308594, 52.58100128173828, -5.098999977111816], 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"AQKSVKISDDISITQLSDKVYTYVSLAEIEGWGMVPSNGMIVINNHQAALLDTPINDAQTEMLVNWVTDSLHAKVTTFIPNHWHGDCIGGLGYLQRKGVQSYANQMTIDLAKEKGLPVPEHGFTDSLTVSLDGMPLQCYYLGGGHATDNIVVWLPTENILFGGCMLKDNQTTSIGNISDADVTAWPKTLDKVKAKFPSARYVVPGHGNYGGTELIEHTKQIVNQYIESTSKP"}] \ No newline at end of file diff --git a/esm/source/tests/test_alphabet.py b/esm/source/tests/test_alphabet.py new file mode 100644 index 0000000000000000000000000000000000000000..e200becaf3d368361d8b58b2ff4155343ad4b820 --- /dev/null +++ b/esm/source/tests/test_alphabet.py @@ -0,0 +1,87 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +def _test_esm1b(alphabet): + import torch + + batch_converter = alphabet.get_batch_converter() + + data = [ + ("protein1", "MKTVRQG"), + ("protein2 with mask", "KALTAISQP"), + ("protein3", "K A I S Q"), + ] + _, _, batch_tokens = batch_converter(data) + expected_tokens = torch.tensor( + [ + [0, 20, 15, 11, 7, 10, 16, 6, 2, 1, 1, 1], + [0, 15, 5, 4, 11, 5, 32, 12, 8, 16, 14, 2], + [0, 15, 5, 32, 12, 8, 16, 2, 1, 1, 1, 1], + ] + ) + assert torch.allclose(batch_tokens, expected_tokens) + + +def _test_esm1b_truncation(alphabet): + import torch + + batch_converter = alphabet.get_batch_converter(truncation_seq_length=10) + + data = [ + ("protein1", "MKTVRQGMKTVRQG"), + ("protein2 with mask", "KALTAISQPISQP"), + ("protein3", "K A I S Q"), + ] + _, _, batch_tokens = batch_converter(data) + expected_tokens = torch.tensor( + [ + [0, 20, 15, 11, 7, 10, 16, 6, 20, 15, 11, 2], + [0, 15, 5, 4, 11, 5, 32, 12, 8, 16, 14, 2], + [0, 15, 5, 32, 12, 8, 16, 2, 1, 1, 1, 1], + ] + ) + assert torch.allclose(batch_tokens, expected_tokens) + + +def test_esm1b_alphabet(): + import esm + + _, alphabet = esm.pretrained.esm1b_t33_650M_UR50S() + _test_esm1b(alphabet) + _test_esm1b_truncation(alphabet) + + +def test_esm1v_alphabet(): + import esm + + _, alphabet = esm.pretrained.esm1v_t33_650M_UR90S_1() + _test_esm1b(alphabet) + _test_esm1b_truncation(alphabet) + + +def test_esm1_msa1b_alphabet(): + import torch + import esm + + # Load ESM-1b model + _, alphabet = esm.pretrained.esm_msa1b_t12_100M_UR50S() + batch_converter = alphabet.get_batch_converter() + + data = [ + ("protein1", "MKTVRQG"), + ("protein2", "KALTRAI"), + ("protein3", "KAAISQQ"), + ] + _, _, batch_tokens = batch_converter(data) + expected_tokens = torch.tensor( + [ + [ + [0, 20, 15, 11, 7, 10, 16, 6], + [0, 15, 5, 4, 11, 10, 5, 12], + [0, 15, 5, 5, 12, 8, 16, 16], + ] + ] + ) + assert torch.allclose(batch_tokens, expected_tokens) diff --git a/esm/source/tests/test_inverse_folding.py b/esm/source/tests/test_inverse_folding.py new file mode 100644 index 0000000000000000000000000000000000000000..a7bf7f00be2a3093fc19f089efcc2c23980c6735 --- /dev/null +++ b/esm/source/tests/test_inverse_folding.py @@ -0,0 +1,71 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +def test_esm_if1(): + + import json + import numpy as np + from pathlib import Path + from scipy.stats import special_ortho_group + from tqdm import tqdm + import torch + + import esm + import esm.inverse_folding + + example_file = Path(__file__).absolute().parent / "inverse_folding_test_example.json" + with open(example_file) as f: + examples = json.load(f) + + model, alphabet = esm.pretrained.esm_if1_gvp4_t16_142M_UR50() + model = model.eval() + batch_converter = esm.inverse_folding.util.CoordBatchConverter(alphabet) + + with torch.no_grad(): + print('Testing batch inference on 3 examples...') + # Test batch with multiple examples + batch = [(e["coords"], None, e["seq"]) for e in examples[:3]] + coords, confidence, strs, tokens, padding_mask = ( + batch_converter(batch) + ) + prev_output_tokens = tokens[:, :-1] + target = tokens[:, 1:] + logits, _ = model.forward(coords, padding_mask, confidence, + prev_output_tokens) + loss = torch.nn.functional.cross_entropy(logits, target, reduction='none') + coord_mask = torch.all(torch.all(torch.isfinite(coords), dim=-1), dim=-1) + coord_mask = coord_mask[:, 1:-1] + avgloss = torch.sum(loss * coord_mask) / torch.sum(coord_mask) + expected_ppl = 4.40 + np.testing.assert_allclose( + expected_ppl, + torch.exp(avgloss).item(), + atol=1e-02, + ) + + print('Testing on 10 examples from validation set...') + # Test batch with single example + for example in tqdm(examples): + batch = [(example["coords"], None, example["seq"])] + coords, confidence, strs, tokens, padding_mask = ( + batch_converter(batch) + ) + prev_output_tokens = tokens[:, :-1] + target = tokens[:, 1:] + logits, _ = model.forward(coords, padding_mask, confidence, + prev_output_tokens) + assert torch.any(torch.isnan(logits)) == False + + # Test equivariance + R = special_ortho_group.rvs(3) + R = torch.tensor(R, dtype=torch.float32) + coords = torch.matmul(coords, R) + logits_rotated, _ = model.forward(coords, padding_mask, + confidence, prev_output_tokens) + np.testing.assert_allclose( + logits.detach().numpy(), + logits_rotated.detach().numpy(), + atol=1e-01 + ) diff --git a/esm/source/tests/test_load_all.py b/esm/source/tests/test_load_all.py new file mode 100644 index 0000000000000000000000000000000000000000..33e6e4c4cc6d6c342728b961a482cb35a8427e84 --- /dev/null +++ b/esm/source/tests/test_load_all.py @@ -0,0 +1,56 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import pytest +from pathlib import Path +import torch +import esm + +# Directly from hubconf.py +model_names = """ + esm1_t6_43M_UR50S, + esm1_t12_85M_UR50S, + esm1_t34_670M_UR50S, + esm1_t34_670M_UR50D, + esm1_t34_670M_UR100, + esm1b_t33_650M_UR50S, + esm_msa1_t12_100M_UR50S, + esm_msa1b_t12_100M_UR50S, + esm1v_t33_650M_UR90S, + esm1v_t33_650M_UR90S_1, + esm1v_t33_650M_UR90S_2, + esm1v_t33_650M_UR90S_3, + esm1v_t33_650M_UR90S_4, + esm1v_t33_650M_UR90S_5, + esm_if1_gvp4_t16_142M_UR50, + esm2_t6_8M_UR50D, + esm2_t12_35M_UR50D, + esm2_t30_150M_UR50D, + esm2_t33_650M_UR50D, + esm2_t36_3B_UR50D, + esm2_t48_15B_UR50D +""" +model_names = [mn.strip() for mn in model_names.strip(" ,\n").split(",")] + + +@pytest.mark.parametrize("model_name", model_names) +def test_load_hub_fwd_model(model_name: str) -> None: + model, alphabet = getattr(esm.pretrained, model_name)() + # batch_size = 2, seq_len = 3, tokens within vocab + dummy_inp = torch.tensor([[0, 1, 2], [3, 4, 5]]) + if "esm_msa" in model_name: + dummy_inp = dummy_inp.unsqueeze(0) + output = model(dummy_inp) # dict + logits = output["logits"].squeeze(0) + assert logits.shape == (2, 3, len(alphabet)) + + +@pytest.mark.parametrize("model_name", model_names) +def test_load_local(model_name: str) -> None: + # Assumes everything has already been loaded & cached. + local_path = Path.home() / ".cache/torch/hub/checkpoints" / (model_name + ".pt") + if model_name.endswith("esm1v_t33_650M_UR90S"): + return # skip; needs to get rerouted to specific instance + model, alphabet = esm.pretrained.load_model_and_alphabet_local(local_path) diff --git a/esm/source/tests/test_notebooks.py b/esm/source/tests/test_notebooks.py new file mode 100644 index 0000000000000000000000000000000000000000..130e2491cefeb120b1d41c52c33122689b491198 --- /dev/null +++ b/esm/source/tests/test_notebooks.py @@ -0,0 +1,64 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import os +import subprocess +import pytest +from pathlib import Path + +notebook_dir = Path(__file__).parents[1] / "examples" +notebook_fns = notebook_dir.glob("*.ipynb") + + +def convert_notebook_to_py(nb_fn: Path, py_fn: Path) -> None: + """ + From https://stackoverflow.com/questions/17077494/how-do-i-convert-a-ipython-notebook-into-a-python-file-via-commandline + """ + import nbformat + from nbconvert import PythonExporter + + with open(nb_fn) as fh: + nb = nbformat.reads(fh.read(), nbformat.NO_CONVERT) + + exporter = PythonExporter() + source, meta = exporter.from_notebook_node(nb) + + # Skip the magic, which gets converted to `get_ipython()` + source.replace("get_ipython", "# get_ipython") + + with open(py_fn, "w+") as fh: + fh.writelines(source) + + +def run_multiple(cmds): + for cmd in cmds.strip().split("\n"): + print(cmd) + subprocess.run(cmd.strip(), shell=True, check=True) + + +def do_setup(nb_name): + """ Do any setup work; see intro of the notebook """ + if nb_name == "sup_variant_prediction": + cmds = """ + curl -O https://dl.fbaipublicfiles.com/fair-esm/examples/P62593_reprs.tar.gz + tar -xzf P62593_reprs.tar.gz + curl -O https://dl.fbaipublicfiles.com/fair-esm/examples/P62593.fasta + """ + run_multiple(cmds) + else: + print(f"No setup work for {nb_name}") + + +@pytest.mark.parametrize("nb_fn", list(notebook_fns)) +def test_run_notebook(nb_fn: Path, tmp_path: Path): + """ Simply make sure the notebooks run from a-z """ + py_fn = tmp_path / (nb_fn.stem + ".py") + print(py_fn) + convert_notebook_to_py(nb_fn, py_fn) + os.chdir(notebook_dir) + do_setup(nb_fn.stem) + _globals = {} + exec(py_fn.read_text(), _globals) + # No asserts, just running is enough for now diff --git a/esm/source/tests/test_readme.py b/esm/source/tests/test_readme.py new file mode 100644 index 0000000000000000000000000000000000000000..7ed36bd6a3eaab75090398259ea011004ac52e6f --- /dev/null +++ b/esm/source/tests/test_readme.py @@ -0,0 +1,184 @@ +# Copyright (c) Meta Platforms, Inc. and affiliates. +# +# This source code is licensed under the MIT license found in the +# LICENSE file in the root directory of this source tree. + +import sys +import subprocess +import tempfile +import requests +import shutil +from pathlib import Path +import torch +import esm + + +def test_readme_1(): + import torch + + model, alphabet = torch.hub.load("facebookresearch/esm:main", "esm2_t33_650M_UR50D") + + +def test_readme_2(): + import torch + import esm + + # Load ESM-2 model + model, alphabet = esm.pretrained.esm2_t33_650M_UR50D() + batch_converter = alphabet.get_batch_converter() + model.eval() # disables dropout for deterministic results + + # Prepare data (first 2 sequences from ESMStructuralSplitDataset superfamily / 4) + data = [ + ("protein1", "MKTVRQERLKSIVRILERSKEPVSGAQLAEELSVSRQVIVQDIAYLRSLGYNIVATPRGYVLAGG"), + ("protein2", "KALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEE"), + ("protein2 with mask","KALTARQQEVFDLIRDISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEE"), + ("protein3", "K A I S Q"), + ] + batch_labels, batch_strs, batch_tokens = batch_converter(data) + batch_lens = (batch_tokens != alphabet.padding_idx).sum(1) + + # Extract per-residue representations (on CPU) + with torch.no_grad(): + results = model(batch_tokens, repr_layers=[33], return_contacts=True) + token_representations = results["representations"][33] + + # Generate per-sequence representations via averaging + # NOTE: token 0 is always a beginning-of-sequence token, so the first residue is token 1. + sequence_representations = [] + for i, tokens_len in enumerate(batch_lens): + sequence_representations.append(token_representations[i, 1 : tokens_len - 1].mean(0)) + + # Look at the unsupervised self-attention map contact predictions + try: + import matplotlib.pyplot as plt + for (_, seq), tokens_len, attention_contacts in zip(data, batch_lens, results["contacts"]): + plt.matshow(attention_contacts[: tokens_len, : tokens_len]) + plt.title(seq) + plt.show() + except ImportError: + pass # dont need mpl to run test + + +def _run_py_cmd(cmd, **kwargs): + this_python = sys.executable + cmd.replace("python", this_python) + subprocess.run(cmd, shell=True, check=True, **kwargs) + + +def test_readme_esmfold(): + import torch + import esm + + model = esm.pretrained.esmfold_v1() + model = model.eval().cuda() + + sequence = "MKTVRQERLKSIVRILERSKEPVSGAQLAEELSVSRQVIVQDIAYLRSLGYNIVATPRGYVLAGG" + # Multimer prediction can be done with chains separated by ':' + + with torch.no_grad(): + output = model.infer_pdb(sequence) + + with open("result.pdb", "w") as f: + f.write(output) + + #import biotite.structure.io as bsio + #struct = bsio.load_structure("result.pdb", extra_fields=["b_factor"]) + #print(struct.b_factor.mean()) # this will be the pLDDT + with open("result.pdb") as f: + lines = [line for line in f.readlines() if line.startswith('ATOM')] + bfactors = [float(line[60:66]) for line in lines] + assert torch.allclose(torch.Tensor(bfactors).mean(), torch.Tensor([88.3]), atol=1e-1) + + +def test_readme_3(): + # NOTE modification on copy paste from README for speed: + # * some_proteins -> few_proteins (subset) + # * I computed reference values a while ago for: esm1b -> esm1 and layers 33 -> 34 + cmd = """ +python scripts/extract.py esm1_t34_670M_UR50S examples/data/few_proteins.fasta examples/data/few_proteins_emb_esm1/ \ + --repr_layers 0 33 34 --include mean per_tok +""" + _run_py_cmd(cmd) + confirm_all_tensors_equal( + "examples/few_proteins_emb_esm1/", + "https://dl.fbaipublicfiles.com/fair-esm/tests/some_proteins_emb_esm1_t34_670M_UR50S_ref", + ) + + +def assert_pt_file_equal(f, fref): + a = torch.load(f) + b = torch.load(fref) + # set intersection of dict keys: + which_layers = a["representations"].keys() & b["representations"].keys() + assert which_layers, "Expected at least one layer appearing in both dumps" + for layer in which_layers: + assert torch.allclose(a["representations"][layer], b["representations"][layer], atol=1e-3) + + +def confirm_all_tensors_equal(local_dir: str, ref_dir: str) -> None: + # TODO use pytest built-in fixtures for tmp_path https://docs.pytest.org/en/6.2.x/fixture.html#fixtures + for fn in Path(local_dir).glob("*.pt"): + with tempfile.NamedTemporaryFile(mode="w+b", prefix=fn.name) as f: + ref_url = f"{ref_dir}/{fn.name}" + with requests.get(ref_url, stream=True) as r: + shutil.copyfileobj(r.raw, f) + f.seek(0) + assert_pt_file_equal(fn, f) + + +def test_msa_transformers(): + _test_msa_transformer(*esm.pretrained.esm_msa1_t12_100M_UR50S()) + _test_msa_transformer(*esm.pretrained.esm_msa1b_t12_100M_UR50S()) + + +def _test_msa_transformer(model, alphabet): + batch_converter = alphabet.get_batch_converter() + # Make an "MSA" of size 3 + data = [ + ("protein1", "MKTVRQERLKSIVRILERSKEPVSGAQLAEELSVSRQVIVQDIAYLRSLGYNIVATPRGYVLAGG"), + ("protein2", "MHTVRQSRLKSIVRILEMSKEPVSGAQLAEELSVSRQVIVQDIAYLRSLGYNIVATPRGYVLAGG"), + ("protein3", "MHTVRQSRLKSIVRILEMSKEPVSGAQL---LSVSRQVIVQDIAYLRSLGYNIVAT----VLAGG"), + ] + batch_labels, batch_strs, batch_tokens = batch_converter(data) + + with torch.no_grad(): + results = model(batch_tokens, repr_layers=[12], return_contacts=True) + token_representations = results["representations"][12] + assert token_representations.shape == (1, 3, 66, 768) + + +def test_variant_readme_1(): + cmd = """ +python predict.py \ + --model-location esm1v_t33_650M_UR90S_1 esm1v_t33_650M_UR90S_2 esm1v_t33_650M_UR90S_3 esm1v_t33_650M_UR90S_4 esm1v_t33_650M_UR90S_5 \ + --sequence HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW \ + --dms-input ./data/BLAT_ECOLX_Ranganathan2015.csv \ + --mutation-col mutant \ + --dms-output ./data/BLAT_ECOLX_Ranganathan2015_labeled.csv \ + --offset-idx 24 \ + --scoring-strategy wt-marginals + """ + _run_py_cmd(cmd, cwd="examples/variant-prediction/") + + +def test_variant_readme_2(): + cmd = """ +python predict.py \ + --model-location esm_msa1b_t12_100M_UR50S \ + --sequence HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW \ + --dms-input ./data/BLAT_ECOLX_Ranganathan2015.csv \ + --mutation-col mutant \ + --dms-output ./data/BLAT_ECOLX_Ranganathan2015_labeled.csv \ + --offset-idx 24 \ + --scoring-strategy masked-marginals \ + --msa-path ./data/BLAT_ECOLX_1_b0.5.a3m + """ + _run_py_cmd(cmd, cwd="examples/variant-prediction/") + + +if __name__ == "__main__": + confirm_all_tensors_equal( + "examples/few_proteins_emb_esm1/", + "https://dl.fbaipublicfiles.com/fair-esm/tests/some_proteins_emb_esm1_t34_670M_UR50S_ref/", + ) diff --git a/requirements.txt b/requirements.txt new file mode 100644 index 0000000000000000000000000000000000000000..a8be83b46902e68567155421563e3c7320acbba8 --- /dev/null +++ b/requirements.txt @@ -0,0 +1,2 @@ + fastapi + uvicorn[standard] \ No newline at end of file